From 0a99c0139b7c5d4943b75eb8816fd427c5d8f0cc Mon Sep 17 00:00:00 2001 From: psalguerog <59012739+psalguerog@users.noreply.github.com> Date: Tue, 12 May 2020 12:31:18 +0200 Subject: [PATCH] DFI for Time Course Experiments - Fixed -DFI for Time Course Experiments fixed . -Contact page updated. -Go.obo file updated. -Files added. --- SubTabDFIResults.java | 3 +- Tappas.java | 2 +- resources/go.obo | 608643 +++++++++++++++++++++++++++++++ resources/hs_ncbi_genes.tsv | 60088 +++ resources/mm_ncbi_genes.tsv | 69103 ++++ resources/resource_v1.0.1.txt | 0 resources/web/contact.html | 2 +- resources/webFiles.txt~ | 9 + scripts/DFI.R | 254 +- scripts/DFI_TimeCourse.R | 161 +- 10 files changed, 738120 insertions(+), 145 deletions(-) create mode 100644 resources/go.obo create mode 100644 resources/hs_ncbi_genes.tsv create mode 100644 resources/mm_ncbi_genes.tsv create mode 100644 resources/resource_v1.0.1.txt create mode 100644 resources/webFiles.txt~ diff --git a/SubTabDFIResults.java b/SubTabDFIResults.java index 7f701de..dcfe90d 100644 --- a/SubTabDFIResults.java +++ b/SubTabDFIResults.java @@ -571,10 +571,11 @@ protected Void call() throws Exception { lst.add("-r" + r); } lst.add("-s" + dfiParams.sigValue); - lst.add("-x" + project.data.getMatrixDFIFilepath(analysisId)); lst.add("-c" + project.data.getDFITotalFeaturesFilepath(analysisId)); lst.add("-g1" + project.data.getDFITestFeaturesFilepath(analysisId)); lst.add("-g2" + project.data.getDFITestGenesFilepath(analysisId)); + + lst.add("-x" + project.data.getMatrixDFIFilepath(analysisId)); lst.add("-lt" + trans); lst.add("-lp" + proteins); diff --git a/Tappas.java b/Tappas.java index 59e52b7..a7ad567 100644 --- a/Tappas.java +++ b/Tappas.java @@ -51,7 +51,7 @@ public class Tappas extends Application { public static final String APP_NAME = "tappas"; public static final int APP_MAJOR_VER = 1; public static final int APP_MINOR_VER = 0; - public static final int APP_STRREV = 0; + public static final int APP_STRREV = 1; public static final String RES_VER_FILE = "resource_v" + APP_MAJOR_VER + "." + APP_MINOR_VER + "." + APP_STRREV + ".txt"; public static final String APP_LOCK_FILE = ".tappas.lock.prm"; public static final String APP_PORT_PARAM = "port"; diff --git a/resources/go.obo b/resources/go.obo new file mode 100644 index 0000000..05f1730 --- /dev/null +++ b/resources/go.obo @@ -0,0 +1,608643 @@ +format-version: 1.2 +data-version: releases/2020-05-02 +subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation" +subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation" +subsetdef: goslim_agr "AGR slim" +subsetdef: goslim_aspergillus "Aspergillus GO slim" +subsetdef: goslim_candida "Candida GO slim" +subsetdef: goslim_chembl "ChEMBL protein targets summary" +subsetdef: goslim_drosophila "Drosophila GO slim" +subsetdef: goslim_flybase_ribbon "FlyBase Drosophila GO ribbon slim" +subsetdef: goslim_generic "Generic GO slim" +subsetdef: goslim_metagenomics "Metagenomics GO slim" +subsetdef: goslim_mouse "Mouse GO slim" +subsetdef: goslim_pir "PIR GO slim" +subsetdef: goslim_plant "Plant GO slim" +subsetdef: goslim_pombe "Fission yeast GO slim" +subsetdef: goslim_synapse "synapse GO slim" +subsetdef: goslim_yeast "Yeast GO slim" +synonymtypedef: syngo_official_label "label approved by the SynGO project" +synonymtypedef: systematic_synonym "Systematic synonym" EXACT +default-namespace: gene_ontology +remark: cvs version: $Revision: 38972$ +remark: Includes Ontology(OntologyID(OntologyIRI())) [Axioms: 18 Logical Axioms: 0] +ontology: go +property_value: http://purl.org/dc/elements/1.1/description "The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms." xsd:string +property_value: http://purl.org/dc/elements/1.1/title "Gene Ontology" xsd:string +property_value: http://purl.org/dc/terms/license http://creativecommons.org/licenses/by/4.0/ + +[Term] +id: GO:0000001 +name: mitochondrion inheritance +namespace: biological_process +def: "The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:11389764] +synonym: "mitochondrial inheritance" EXACT [] +is_a: GO:0048308 ! organelle inheritance +is_a: GO:0048311 ! mitochondrion distribution + +[Term] +id: GO:0000002 +name: mitochondrial genome maintenance +namespace: biological_process +def: "The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome." [GOC:ai, GOC:vw] +is_a: GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0000003 +name: reproduction +namespace: biological_process +alt_id: GO:0019952 +alt_id: GO:0050876 +def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +synonym: "reproductive physiological process" EXACT [] +xref: Wikipedia:Reproduction +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase + +[Term] +id: GO:0000005 +name: obsolete ribosomal chaperone activity +namespace: molecular_function +def: "OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function." [GOC:jl, PMID:12150913] +comment: This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function. +synonym: "ribosomal chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0042254 +consider: GO:0044183 +consider: GO:0051082 + +[Term] +id: GO:0000006 +name: high-affinity zinc transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.5.1.1] +synonym: "high affinity zinc uptake transmembrane transporter activity" EXACT [] +synonym: "high-affinity zinc uptake transmembrane transporter activity" RELATED [] +is_a: GO:0005385 ! zinc ion transmembrane transporter activity + +[Term] +id: GO:0000007 +name: low-affinity zinc ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005385 ! zinc ion transmembrane transporter activity + +[Term] +id: GO:0000008 +name: obsolete thioredoxin +namespace: molecular_function +alt_id: GO:0000013 +def: "OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol." [GOC:kd] +comment: This term was made obsolete because it represents gene products. +synonym: "thioredoxin" EXACT [] +is_obsolete: true +consider: GO:0003756 +consider: GO:0015036 + +[Term] +id: GO:0000009 +name: alpha-1,6-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage." [GOC:mcc, PMID:2644248] +synonym: "1,6-alpha-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.232 +xref: Reactome:R-HSA-449718 "Addition of a third mannose to the N-glycan precursor by ALG2" +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0000010 +name: trans-hexaprenyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate." [PMID:9708911] +xref: KEGG_REACTION:R05612 +xref: RHEA:20836 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0000011 +name: vacuole inheritance +namespace: biological_process +def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069] +is_a: GO:0007033 ! vacuole organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0000012 +name: single strand break repair +namespace: biological_process +def: "The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair." [http://www.ultranet.com/~jkimball/BiologyPages/D/DNArepair.html] +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0000014 +name: single-stranded DNA endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks." [GOC:mah] +synonym: "single-stranded DNA specific endodeoxyribonuclease activity" RELATED [] +synonym: "ssDNA-specific endodeoxyribonuclease activity" RELATED [GOC:mah] +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0000015 +name: phosphopyruvate hydratase complex +namespace: cellular_component +def: "A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water." [GOC:jl, ISBN:0198506732] +subset: goslim_metagenomics +synonym: "enolase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0000016 +name: lactase activity +namespace: molecular_function +def: "Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose." [PMID:12023280] +synonym: "lactase-phlorizin hydrolase activity" BROAD [] +synonym: "lactose galactohydrolase activity" EXACT [] +xref: EC:3.2.1.108 +xref: MetaCyc:LACTASE-RXN +xref: Reactome:R-HSA-189062 "lactose + H2O => D-glucose + D-galactose" +xref: Reactome:R-HSA-5658001 "Defective LCT does not hydrolyze Lac" +xref: RHEA:10076 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0000017 +name: alpha-glucoside transport +namespace: biological_process +def: "The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration." [GOC:jl, http://www.biochem.purdue.edu/, ISBN:0198506732] +is_a: GO:0042946 ! glucoside transport + +[Term] +id: GO:0000018 +name: regulation of DNA recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006310 ! DNA recombination +relationship: regulates GO:0006310 ! DNA recombination + +[Term] +id: GO:0000019 +name: regulation of mitotic recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA recombination during mitosis." [GOC:go_curators] +synonym: "regulation of recombination within rDNA repeats" NARROW [] +is_a: GO:0000018 ! regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006312 ! mitotic recombination +relationship: regulates GO:0006312 ! mitotic recombination + +[Term] +id: GO:0000020 +name: obsolete negative regulation of recombination within rDNA repeats +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA." [GOC:go_curators, ISBN:0198506732] +comment: This term was made obsolete because it describes a substrate-specific process. +synonym: "negative regulation of recombination within rDNA repeats" EXACT [] +is_obsolete: true +consider: GO:0045950 + +[Term] +id: GO:0000022 +name: mitotic spindle elongation +namespace: biological_process +def: "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B." [GOC:mtg_cell_cycle, GOC:vw] +synonym: "spindle elongation during mitosis" EXACT [] +is_a: GO:0051231 ! spindle elongation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051231 ! spindle elongation +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation +relationship: part_of GO:0007052 ! mitotic spindle organization + +[Term] +id: GO:0000023 +name: maltose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch." [GOC:jl, ISBN:0198506732] +synonym: "malt sugar metabolic process" EXACT [] +synonym: "malt sugar metabolism" EXACT [] +synonym: "maltose metabolism" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process + +[Term] +id: GO:0000024 +name: maltose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)." [GOC:jl, ISBN:0198506732] +synonym: "malt sugar biosynthesis" EXACT [] +synonym: "malt sugar biosynthetic process" EXACT [] +synonym: "maltose anabolism" EXACT [] +synonym: "maltose biosynthesis" EXACT [] +synonym: "maltose formation" EXACT [] +synonym: "maltose synthesis" EXACT [] +is_a: GO:0000023 ! maltose metabolic process +is_a: GO:0046351 ! disaccharide biosynthetic process + +[Term] +id: GO:0000025 +name: maltose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)." [GOC:jl, ISBN:0198506732] +synonym: "malt sugar catabolic process" EXACT [] +synonym: "malt sugar catabolism" EXACT [] +synonym: "maltose breakdown" EXACT [] +synonym: "maltose degradation" EXACT [] +synonym: "maltose hydrolysis" NARROW [] +xref: MetaCyc:MALTOSECAT-PWY +is_a: GO:0000023 ! maltose metabolic process +is_a: GO:0046352 ! disaccharide catabolic process + +[Term] +id: GO:0000026 +name: alpha-1,2-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage." [GOC:mcc, PMID:10521541] +xref: Reactome:R-HSA-446187 "ALG11 transfers the fourth and fifth Man to the N-glycan precursor" +xref: Reactome:R-HSA-446215 "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1" +xref: Reactome:R-HSA-446216 "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1" +xref: Reactome:R-HSA-4551297 "Defective ALG11 does not transfer Man to the N-glycan precursor" +xref: Reactome:R-HSA-4720478 "Defective ALG9 does not add the seventh mannose to the N-glycan precursor" +xref: Reactome:R-HSA-9035514 "Defective ALG9 does not add the last mannose to the N-glycan precursor" +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0000027 +name: ribosomal large subunit assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit." [GOC:jl] +synonym: "50S ribosomal subunit assembly" NARROW [GOC:mah] +synonym: "60S ribosomal subunit assembly" NARROW [GOC:mah] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0042255 ! ribosome assembly +relationship: part_of GO:0042273 ! ribosomal large subunit biogenesis + +[Term] +id: GO:0000028 +name: ribosomal small subunit assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit." [GOC:jl] +synonym: "30S ribosomal subunit assembly" NARROW [GOC:mah] +synonym: "40S ribosomal subunit assembly" NARROW [GOC:mah] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0042255 ! ribosome assembly +relationship: part_of GO:0042274 ! ribosomal small subunit biogenesis + +[Term] +id: GO:0000030 +name: mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai, GOC:cjm] +xref: Reactome:R-HSA-162797 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI" +xref: Reactome:R-HSA-162830 "glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate" +xref: Reactome:R-HSA-446198 "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1" +xref: Reactome:R-HSA-4720497 "Defective ALG12 does not add mannose to the N-glycan precursor" +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups +relationship: part_of GO:0097502 ! mannosylation + +[Term] +id: GO:0000031 +name: mannosylphosphate transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannosylphosphate group from one compound to another." [GOC:jl] +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0000032 +name: cell wall mannoprotein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues." [GOC:ai] +synonym: "cell wall mannoprotein anabolism" EXACT [] +synonym: "cell wall mannoprotein biosynthesis" EXACT [] +synonym: "cell wall mannoprotein formation" EXACT [] +synonym: "cell wall mannoprotein synthesis" EXACT [] +is_a: GO:0006057 ! mannoprotein biosynthetic process +is_a: GO:0031506 ! cell wall glycoprotein biosynthetic process + +[Term] +id: GO:0000033 +name: alpha-1,3-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage." [GOC:mcc, PMID:10521541] +xref: Reactome:R-HSA-446188 "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1" +xref: Reactome:R-HSA-446208 "Addition of a second mannose to the N-glycan precursor by ALG2" +xref: Reactome:R-HSA-4549368 "Defective ALG2 does not transfer a second Man to N-glycan precursor" +xref: Reactome:R-HSA-4720473 "Defective ALG3 does not add mannose to the N-glycan precursor" +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0000034 +name: adenine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3." [EC:3.5.4.2] +synonym: "ADase activity" EXACT [EC:3.5.4.2] +synonym: "adenase activity" EXACT [EC:3.5.4.2] +synonym: "adenine aminase activity" EXACT [EC:3.5.4.2] +synonym: "adenine aminohydrolase activity" EXACT [EC:3.5.4.2] +xref: EC:3.5.4.2 +xref: MetaCyc:ADENINE-DEAMINASE-RXN +xref: RHEA:23688 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0000035 +name: acyl binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid." [GOC:curators, ISBN:0198506732] +synonym: "acyl-CoA or acyl binding" BROAD [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0000036 +name: acyl carrier activity +namespace: molecular_function +def: "Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis." [GOC:jl, GOC:vw] +synonym: "ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process" EXACT [] +is_a: GO:0044620 ! ACP phosphopantetheine attachment site binding +is_a: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: part_of GO:0006633 ! fatty acid biosynthetic process +relationship: part_of GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0000038 +name: very long-chain fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22." [GOC:hjd] +synonym: "very long chain fatty acid metabolic process" EXACT [GOC:bf] +synonym: "very-long-chain fatty acid metabolic process" EXACT [] +synonym: "very-long-chain fatty acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0000039 +name: obsolete plasma membrane long-chain fatty acid transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a gene product and it contains component information. +synonym: "plasma membrane long-chain fatty acid transporter" EXACT [] +is_obsolete: true +consider: GO:0005324 +consider: GO:0005886 + +[Term] +id: GO:0000041 +name: transition metal ion transport +namespace: biological_process +def: "The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] +synonym: "transition metal transport" EXACT [] +is_a: GO:0030001 ! metal ion transport + +[Term] +id: GO:0000044 +name: obsolete ascorbate stabilization +namespace: biological_process +def: "OBSOLETE. The reduction of the ascorbate free radical to a stable form." [GOC:ai, GOC:mtg_electron_transport] +comment: This term was made obsolete because it is defined as a function term and is in the process ontology. +synonym: "ascorbate stabilization" EXACT [] +synonym: "vitamin C stabilization" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000045 +name: autophagosome assembly +namespace: biological_process +def: "The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm." [GOC:autophagy, PMID:9412464] +synonym: "autophagic vacuole assembly" EXACT [GOC:autophagy] +synonym: "autophagic vacuole formation" RELATED [GOC:mah] +synonym: "autophagosome biosynthesis" EXACT [] +synonym: "autophagosome formation" EXACT [] +synonym: "PAS formation" NARROW [] +is_a: GO:0070925 ! organelle assembly +is_a: GO:1905037 ! autophagosome organization +relationship: has_part GO:0019778 ! Atg12 activating enzyme activity +relationship: has_part GO:0019786 ! Atg8-specific protease activity +relationship: has_part GO:0061651 ! Atg12 conjugating enzyme activity +relationship: has_part GO:0061660 ! Atg12 ligase activity + +[Term] +id: GO:0000047 +name: obsolete Rieske iron-sulfur protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "Rieske iron-sulfur protein" EXACT [] +synonym: "Rieske iron-sulphur protein" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0000048 +name: peptidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2)." [EC:2.3.2.12, PMID:11433365, PMID:9242921] +synonym: "peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity" EXACT [EC:2.3.2.12] +xref: EC:2.3.2.12 +xref: MetaCyc:PEPTIDYLTRANSFERASE-RXN +xref: Reactome:R-HSA-156912 "Peptide transfer from P-site tRNA to the A-site tRNA" +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0000049 +name: tRNA binding +namespace: molecular_function +alt_id: GO:0000946 +def: "Interacting selectively and non-covalently with transfer RNA." [GOC:ai] +synonym: "base pairing with tRNA" NARROW [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0000050 +name: urea cycle +namespace: biological_process +alt_id: GO:0006594 +alt_id: GO:0006871 +def: "The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate." [GOC:pde, GOC:vw, ISBN:0198506732] +synonym: "ornithine cycle" EXACT [] +synonym: "urea biosynthesis" EXACT [] +synonym: "urea biosynthetic process" EXACT [] +xref: Wikipedia:Urea_cycle +is_a: GO:0019627 ! urea metabolic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0000051 +name: obsolete urea cycle intermediate metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations. +synonym: "urea cycle intermediate metabolic process" EXACT [] +synonym: "urea cycle intermediate metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000052 +name: citrulline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins." [ISBN:0198506732] +synonym: "citrulline metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0000053 +name: argininosuccinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate." [ISBN:0198506732] +synonym: "argininosuccinate metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0000054 +name: ribosomal subunit export from nucleus +namespace: biological_process +def: "The directed movement of a ribosomal subunit from the nucleus into the cytoplasm." [GOC:ai] +subset: goslim_yeast +synonym: "ribosomal subunit export from cell nucleus" EXACT [GOC:mah] +synonym: "ribosomal subunit export out of nucleus" EXACT [GOC:mah] +synonym: "ribosomal subunit transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "ribosomal subunit-nucleus export" EXACT [GOC:mah] +synonym: "ribosome export from nucleus" RELATED [GOC:mah, GOC:rb] +is_a: GO:0033750 ! ribosome localization +is_a: GO:0051656 ! establishment of organelle localization +is_a: GO:0071428 ! rRNA-containing ribonucleoprotein complex export from nucleus +relationship: part_of GO:0042254 ! ribosome biogenesis + +[Term] +id: GO:0000055 +name: ribosomal large subunit export from nucleus +namespace: biological_process +alt_id: GO:0000057 +def: "The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm." [GOC:mah] +synonym: "50S ribosomal subunit export from nucleus" NARROW [GOC:mah] +synonym: "60S ribosomal subunit export from nucleus" NARROW [GOC:mah] +synonym: "ribosomal large subunit export from cell nucleus" EXACT [] +synonym: "ribosomal large subunit export out of nucleus" EXACT [] +synonym: "ribosomal large subunit transport from nucleus to cytoplasm" EXACT [] +synonym: "ribosomal large subunit-nucleus export" EXACT [] +is_a: GO:0000054 ! ribosomal subunit export from nucleus + +[Term] +id: GO:0000056 +name: ribosomal small subunit export from nucleus +namespace: biological_process +alt_id: GO:0000058 +def: "The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm." [GOC:mah] +synonym: "30S ribosomal subunit export from nucleus" NARROW [GOC:mah] +synonym: "40S ribosomal subunit export from nucleus" NARROW [GOC:mah] +synonym: "ribosomal small subunit export from cell nucleus" EXACT [] +synonym: "ribosomal small subunit export out of nucleus" EXACT [] +synonym: "ribosomal small subunit transport from nucleus to cytoplasm" EXACT [] +synonym: "ribosomal small subunit-nucleus export" EXACT [] +is_a: GO:0000054 ! ribosomal subunit export from nucleus + +[Term] +id: GO:0000059 +name: obsolete protein import into nucleus, docking +namespace: biological_process +def: "OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex." [GOC:isa_complete, GOC:mah, PMID:14570049, PMID:7878057, PMID:9126736] +comment: This term was made obsolete because the transient assembly is better captured as a protein-protein association, if at all. +synonym: "protein docking during protein import into nucleus" EXACT [] +synonym: "protein docking during protein transport from cytoplasm to nucleus" EXACT [] +synonym: "protein docking during protein-nucleus import" EXACT [] +synonym: "protein transport from cytoplasm to nucleus, docking" EXACT [] +synonym: "protein-nucleus import, docking" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000060 +name: obsolete protein import into nucleus, translocation +namespace: biological_process +def: "OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope." [GOC:curators, ISBN:0198506732, PMID:14570049, PMID:9126736] +comment: This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used. +synonym: "protein import into cell nucleus, translocation" EXACT [] +synonym: "protein translocation during protein import into nucleus" EXACT [] +synonym: "protein translocation during protein transport from cytoplasm to nucleus" EXACT [] +synonym: "protein translocation during protein-nucleus import" EXACT [] +synonym: "protein transport from cytoplasm to nucleus, translocation" EXACT [] +synonym: "protein-nucleus import, translocation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000061 +name: obsolete protein import into nucleus, substrate release +namespace: biological_process +def: "OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex." [GOC:mah, PMID:14570049, PMID:9126736, PMID:9687515] +comment: This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used. +synonym: "protein import into cell nucleus, substrate release" EXACT [] +synonym: "protein substrate release during protein import into nucleus" EXACT [] +synonym: "protein substrate release during protein transport from cytoplasm to nucleus" EXACT [] +synonym: "protein substrate release during protein-nucleus import" EXACT [] +synonym: "protein transport from cytoplasm to nucleus, substrate release" EXACT [] +synonym: "protein-nucleus import, substrate release" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000062 +name: fatty-acyl-CoA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group." [GOC:jl, ISBN:0198506732] +synonym: "acyl-CoA or acyl binding" BROAD [] +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0033218 ! amide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:1901567 ! fatty acid derivative binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0000064 +name: L-ornithine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "histidine/arginine/lysine/ornithine porter activity" RELATED [] +synonym: "L-ornithine transporter activity" BROAD [] +xref: Reactome:R-HSA-70634 "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)" +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:1903352 ! L-ornithine transmembrane transport + +[Term] +id: GO:0000067 +name: obsolete DNA replication and chromosome cycle +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity. +synonym: "DNA replication and chromosome cycle" EXACT [] +is_obsolete: true +consider: GO:0006260 +consider: GO:0007059 +consider: GO:0051276 + +[Term] +id: GO:0000070 +name: mitotic sister chromatid segregation +namespace: biological_process +alt_id: GO:0016359 +def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] +subset: goslim_pombe +synonym: "mitotic chromosome segregation" EXACT [] +synonym: "mitotic sister-chromatid adhesion release" NARROW [] +is_a: GO:0000819 ! sister chromatid segregation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0098813 ! nuclear chromosome segregation +intersection_of: part_of GO:0140014 ! mitotic nuclear division +relationship: part_of GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0000072 +name: obsolete M phase specific microtubule process +namespace: biological_process +def: "OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle." [GOC:mah] +comment: This term was made obsolete because terms already exist for centrosome/spindle organization which would be more suitable for the existing annotations, and the phase could be captured as an annotation extension if necessary. +synonym: "M phase specific microtubule process" EXACT [] +synonym: "M-phase specific microtubule process" EXACT [] +is_obsolete: true +consider: GO:0007017 + +[Term] +id: GO:0000073 +name: initial mitotic spindle pole body separation +namespace: biological_process +alt_id: GO:0030475 +def: "The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB." [GOC:sgd_curators, GOC:vw] +is_a: GO:0110100 ! spindle pole body separation +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0061804 ! mitotic spindle formation (spindle phase one) +relationship: part_of GO:1905047 ! mitotic spindle pole body organization + +[Term] +id: GO:0000075 +name: cell cycle checkpoint +namespace: biological_process +alt_id: GO:0031576 +alt_id: GO:0071779 +def: "A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." [GOC:mtg_cell_cycle] +comment: This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here. +subset: gocheck_do_not_manually_annotate +synonym: "G1/S checkpoint" NARROW [] +synonym: "G1/S transition checkpoint" NARROW [] +synonym: "G2/M checkpoint" NARROW [] +synonym: "G2/M transition checkpoint" NARROW [] +xref: Wikipedia:Cell_cycle_checkpoint +is_a: GO:0009987 ! cellular process +is_a: GO:0045786 ! negative regulation of cell cycle + +[Term] +id: GO:0000076 +name: DNA replication checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:curators, GOC:rn, PMID:11728327, PMID:12537518] +is_a: GO:0031570 ! DNA integrity checkpoint + +[Term] +id: GO:0000077 +name: DNA damage checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds." [GOC:mtg_cell_cycle] +synonym: "DNA damage response, signal transduction resulting in cell cycle arrest" NARROW [] +xref: Wikipedia:DNA_damage_checkpoint +xref: Wikipedia:Postreplication_checkpoint +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0031570 ! DNA integrity checkpoint + +[Term] +id: GO:0000078 +name: obsolete cytokinesis after mitosis checkpoint +namespace: biological_process +def: "OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis." [GOC:mtg_cell_cycle] +comment: The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning. +synonym: "cell morphogenesis checkpoint" EXACT [GOC:dph, GOC:vw] +synonym: "cell shape checkpoint" EXACT [] +is_obsolete: true +consider: GO:0044878 +consider: GO:0044879 + +[Term] +id: GO:0000079 +name: regulation of cyclin-dependent protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity." [GOC:go_curators, GOC:pr] +synonym: "regulation of CDK activity" EXACT [] +synonym: "regulation of cyclin-dependent protein kinase activity" BROAD [] +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +is_a: GO:1904029 ! regulation of cyclin-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity +relationship: regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0000080 +name: mitotic G1 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "G1 phase of mitotic cell cycle" EXACT [] +is_a: GO:0051318 ! G1 phase +relationship: part_of GO:0051329 ! mitotic interphase + +[Term] +id: GO:0000082 +name: G1/S transition of mitotic cell cycle +namespace: biological_process +def: "The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated." [GOC:mtg_cell_cycle] +is_a: GO:0044772 ! mitotic cell cycle phase transition +is_a: GO:0044843 ! cell cycle G1/S phase transition +intersection_of: GO:0044843 ! cell cycle G1/S phase transition +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0000083 +name: regulation of transcription involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: part_of GO:0000082 ! G1/S transition of mitotic cell cycle +relationship: part_of GO:0000082 ! G1/S transition of mitotic cell cycle + +[Term] +id: GO:0000084 +name: mitotic S phase +namespace: biological_process +def: "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "S phase of mitotic cell cycle" EXACT [] +synonym: "S-phase of mitotic cell cycle" EXACT [] +is_a: GO:0051320 ! S phase +relationship: part_of GO:0051329 ! mitotic interphase + +[Term] +id: GO:0000085 +name: mitotic G2 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "G2 phase of mitotic cell cycle" EXACT [] +is_a: GO:0051319 ! G2 phase +relationship: part_of GO:0051329 ! mitotic interphase + +[Term] +id: GO:0000086 +name: G2/M transition of mitotic cell cycle +namespace: biological_process +def: "The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex." [GOC:mtg_cell_cycle] +synonym: "mitotic G2/M transition" EXACT [] +is_a: GO:0044772 ! mitotic cell cycle phase transition +is_a: GO:0044839 ! cell cycle G2/M phase transition +intersection_of: GO:0044839 ! cell cycle G2/M phase transition +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0000087 +name: mitotic M phase +namespace: biological_process +def: "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "M phase of mitotic cell cycle" EXACT [] +synonym: "M-phase of mitotic cell cycle" EXACT [] +is_a: GO:0000279 ! M phase +is_a: GO:0098763 ! mitotic cell cycle phase +intersection_of: GO:0000279 ! M phase +intersection_of: happens_during GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0000088 +name: mitotic prophase +namespace: biological_process +def: "The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051324 ! prophase +relationship: part_of GO:0000087 ! mitotic M phase + +[Term] +id: GO:0000089 +name: mitotic metaphase +namespace: biological_process +def: "The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051323 ! metaphase +relationship: part_of GO:0000087 ! mitotic M phase + +[Term] +id: GO:0000090 +name: mitotic anaphase +namespace: biological_process +def: "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051322 ! anaphase +relationship: part_of GO:0000087 ! mitotic M phase + +[Term] +id: GO:0000091 +name: mitotic anaphase A +namespace: biological_process +def: "The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0000090 ! mitotic anaphase + +[Term] +id: GO:0000092 +name: mitotic anaphase B +namespace: biological_process +def: "The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0000090 ! mitotic anaphase + +[Term] +id: GO:0000093 +name: mitotic telophase +namespace: biological_process +def: "The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051326 ! telophase +relationship: part_of GO:0000087 ! mitotic M phase + +[Term] +id: GO:0000094 +name: obsolete septin assembly and septum formation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was not defined and the string name implied two separate processes. +synonym: "septin assembly and septum formation" EXACT [] +is_obsolete: true +consider: GO:0000917 +consider: GO:0000918 +consider: GO:0000921 + +[Term] +id: GO:0000095 +name: S-adenosyl-L-methionine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015177 +def: "Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism." [GOC:ai] +synonym: "S-adenosyl methionine permease activity" EXACT [] +synonym: "S-adenosyl methionine transporter activity" EXACT [] +synonym: "S-adenosylmethionine permease activity" EXACT [] +synonym: "S-adenosylmethionine transmembrane transporter activity" EXACT [] +synonym: "S-adenosylmethionine transporter activity" BROAD [] +synonym: "SAM transmembrane transporter activity" EXACT [] +xref: Reactome:R-HSA-8855062 "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy" +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:1901962 ! S-adenosyl-L-methionine transmembrane transport + +[Term] +id: GO:0000096 +name: sulfur amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine." [GOC:ai] +synonym: "sulfur amino acid metabolism" EXACT [] +synonym: "sulphur amino acid metabolic process" EXACT [] +synonym: "sulphur amino acid metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0000097 +name: sulfur amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine." [GOC:ai] +synonym: "sulfur amino acid anabolism" EXACT [] +synonym: "sulfur amino acid biosynthesis" EXACT [] +synonym: "sulfur amino acid formation" EXACT [] +synonym: "sulfur amino acid synthesis" EXACT [] +synonym: "sulphur amino acid biosynthesis" EXACT [] +synonym: "sulphur amino acid biosynthetic process" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0000098 +name: sulfur amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine." [GOC:ai] +synonym: "sulfur amino acid breakdown" EXACT [] +synonym: "sulfur amino acid catabolism" EXACT [] +synonym: "sulfur amino acid degradation" EXACT [] +synonym: "sulphur amino acid catabolic process" EXACT [] +synonym: "sulphur amino acid catabolism" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0000099 +name: sulfur amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "sulfur amino acid transporter activity" BROAD [] +synonym: "sulphur amino acid transmembrane transporter activity" EXACT [] +synonym: "sulphur amino acid transporter activity" BROAD [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity + +[Term] +id: GO:0000100 +name: S-methylmethionine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015178 +def: "Enables the transfer of S-methylmethionine from one side of a membrane to the other." [GOC:ai] +synonym: "S-methylmethionine permease activity" EXACT [] +synonym: "S-methylmethionine transporter activity" BROAD [] +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0015806 ! S-methylmethionine transport + +[Term] +id: GO:0000101 +name: sulfur amino acid transport +namespace: biological_process +def: "The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "sulphur amino acid transport" EXACT [] +is_a: GO:0006865 ! amino acid transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0000102 +name: L-methionine secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "L-methionine porter activity" RELATED [] +is_a: GO:0005294 ! neutral L-amino acid secondary active transmembrane transporter activity +is_a: GO:0015191 ! L-methionine transmembrane transporter activity +is_a: GO:1901680 ! sulfur-containing amino acid secondary active transmembrane transporter activity + +[Term] +id: GO:0000103 +name: sulfate assimilation +namespace: biological_process +alt_id: GO:0019378 +def: "The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds." [GOC:jl] +synonym: "sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [] +synonym: "sulphate assimilation" EXACT [] +synonym: "sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [] +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0000104 +name: succinate dehydrogenase activity +namespace: molecular_function +alt_id: GO:0019739 +def: "Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor." [GOC:kd] +synonym: "fumarate dehydrogenase activity" EXACT [] +synonym: "fumarate reductase activity" EXACT [] +synonym: "fumaric hydrogenase activity" EXACT [EC:1.3.99.1] +synonym: "succinate oxidoreductase activity" EXACT [] +synonym: "succinate:(acceptor) oxidoreductase activity" EXACT [] +synonym: "succinate:acceptor oxidoreductase activity" EXACT [] +synonym: "succinic acid dehydrogenase activity" EXACT [] +synonym: "succinic dehydrogenase activity" BROAD [] +synonym: "succinodehydrogenase activity" EXACT [] +synonym: "succinyl dehydrogenase activity" EXACT [] +xref: MetaCyc:SUCC-FUM-OXRED-RXN +xref: RHEA:16357 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0000105 +name: histidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:go_curators] +synonym: "histidine anabolism" EXACT [] +synonym: "histidine biosynthesis" EXACT [] +synonym: "histidine formation" EXACT [] +synonym: "histidine synthesis" EXACT [] +xref: MetaCyc:HISTSYN-PWY +is_a: GO:0006547 ! histidine metabolic process +is_a: GO:0009073 ! aromatic amino acid family biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0000107 +name: imidazoleglycerol-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+)." [RHEA:24795] +synonym: "glutamine amidotransferase:cyclase activity" BROAD [] +synonym: "imidazole glycerol phosphate synthase activity" EXACT [] +synonym: "imidazole-glycerol-phosphate synthase activity" RELATED [] +synonym: "imidazoleglycerol phosphate synthase activity" EXACT [] +xref: MetaCyc:GLUTAMIDOTRANS-RXN +xref: RHEA:24795 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0000108 +name: obsolete repairosome +namespace: cellular_component +def: "OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage." [PMID:10681587, PMID:9852079] +comment: This term was made obsolete because 'repairosome' has fallen out of use in the literature, and the large complex described in the definition has not been confirmed to exist. The term has also confused annotators. +synonym: "repairosome" EXACT [] +is_obsolete: true +replaced_by: GO:0000109 + +[Term] +id: GO:0000109 +name: nucleotide-excision repair complex +namespace: cellular_component +def: "Any complex formed of proteins that act in nucleotide-excision repair." [PMID:10915862] +comment: Note that process information is included in the term and definition for the purpose of describing and distinguishing the complex. +subset: goslim_pir +synonym: "UvrB-UvrC complex" NARROW [PMID:12145219] +synonym: "UvrBC complex" NARROW [GOC:bhm, PMID:12145219] +is_a: GO:1990391 ! DNA repair complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000110 +name: nucleotide-excision repair factor 1 complex +namespace: cellular_component +def: "One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively." [PMID:10915862] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +synonym: "NEF1 complex" EXACT [] +synonym: "XPA-ERCC1-ERCC4 complex" EXACT [PMID:8197175] +is_a: GO:0000109 ! nucleotide-excision repair complex + +[Term] +id: GO:0000111 +name: nucleotide-excision repair factor 2 complex +namespace: cellular_component +def: "One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p." [PMID:10915862] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +synonym: "NEF2 complex" EXACT [] +is_a: GO:0000109 ! nucleotide-excision repair complex + +[Term] +id: GO:0000112 +name: nucleotide-excision repair factor 3 complex +namespace: cellular_component +def: "One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p)." [GOC:ew, PMID:10915862, PMID:14500720, PMID:7813015] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +synonym: "NEF3 complex" EXACT [] +is_a: GO:0000109 ! nucleotide-excision repair complex +relationship: has_part GO:0000439 ! transcription factor TFIIH core complex + +[Term] +id: GO:0000113 +name: nucleotide-excision repair factor 4 complex +namespace: cellular_component +def: "One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p." [PMID:10915862] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +synonym: "NEF4 complex" EXACT [] +is_a: GO:0000109 ! nucleotide-excision repair complex + +[Term] +id: GO:0000114 +name: obsolete regulation of transcription involved in G1 phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'. +synonym: "G1-specific transcription in mitotic cell cycle" RELATED [] +synonym: "regulation of transcription from RNA polymerase II promoter during G1 phase of cell cycle" EXACT [] +synonym: "regulation of transcription involved in G1 phase of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0000083 + +[Term] +id: GO:0000115 +name: obsolete regulation of transcription involved in S phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'. +synonym: "regulation of transcription from RNA polymerase II promoter during S-phase of mitotic cell cycle" RELATED [] +synonym: "regulation of transcription involved in S phase of mitotic cell cycle" EXACT [] +synonym: "regulation of transcription involved in S-phase of mitotic cell cycle" EXACT [] +synonym: "S-phase-specific transcription in mitotic cell cycle" RELATED [] +synonym: "S-specific transcription in mitotic cell cycle" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000116 +name: obsolete regulation of transcription involved in G2-phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'. +synonym: "G2-specific transcription in mitotic cell cycle" RELATED [] +synonym: "regulation of transcription from RNA polymerase II during G2-phase of mitotic cell cycle" RELATED [] +synonym: "regulation of transcription involved in G2-phase of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0000117 + +[Term] +id: GO:0000117 +name: regulation of transcription involved in G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle." [GOC:mtg_cell_cycle] +synonym: "G2/M-specific transcription in mitotic cell cycle" RELATED [] +synonym: "regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: part_of GO:0000086 ! G2/M transition of mitotic cell cycle +relationship: part_of GO:0000086 ! G2/M transition of mitotic cell cycle + +[Term] +id: GO:0000118 +name: histone deacetylase complex +namespace: cellular_component +def: "A protein complex that possesses histone deacetylase activity." [GOC:mah] +comment: Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone deacetylase activity ; GO:0004407'. +synonym: "HDAC complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0000120 +name: RNA polymerase I transcription regulator complex +namespace: cellular_component +def: "A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I." [GOC:mah] +synonym: "RNA polymerase I transcription factor complex" NARROW [] +is_a: GO:0005667 ! transcription regulator complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0000121 +name: glycerol-1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate." [EC:3.1.3.21] +synonym: "alpha-glycerol phosphatase activity" EXACT [EC:3.1.3.21] +synonym: "alpha-glycerophosphatase activity" EXACT [EC:3.1.3.21] +synonym: "glycerol 3-phosphatase activity" EXACT [EC:3.1.3.21] +synonym: "glycerol 3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.21] +synonym: "glycerol-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.21] +synonym: "glycerol-3-phosphate phosphatase activity" EXACT [EC:3.1.3.21] +xref: EC:3.1.3.21 +xref: MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN +xref: RHEA:11476 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0000122 +name: negative regulation of transcription by RNA polymerase II +namespace: biological_process +alt_id: GO:0010553 +alt_id: GO:0045816 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II." [GOC:go_curators, GOC:txnOH] +synonym: "down regulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "down regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "down-regulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "down-regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "downregulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "downregulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "inhibition of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "inhibition of transcription from RNA polymerase II promoter" EXACT [] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [] +synonym: "negative regulation of global transcription from Pol II promoter" RELATED [] +synonym: "negative regulation of transcription from Pol II promoter" EXACT [] +synonym: "negative regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global" RELATED [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006366 ! transcription by RNA polymerase II +relationship: negatively_regulates GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0000123 +name: histone acetyltransferase complex +namespace: cellular_component +def: "A protein complex that possesses histone acetyltransferase activity." [GOC:mah] +comment: Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'. +synonym: "histone acetylase complex" EXACT [] +is_a: GO:0031248 ! protein acetyltransferase complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0000124 +name: SAGA complex +namespace: cellular_component +def: "A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8." [PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651] +synonym: "Spt-Ada-Gcn5-acetyltransferase complex" EXACT [] +is_a: GO:0070461 ! SAGA-type complex +is_a: GO:1905368 ! peptidase complex +relationship: has_part GO:0071819 ! DUBm complex + +[Term] +id: GO:0000125 +name: PCAF complex +namespace: cellular_component +def: "A large multiprotein complex that possesses histone acetyltransferase activity and is involved in regulation of transcription. The composition is similar to that of the SAGA complex, but includes fewer Spt and Ada proteins, and more TAFs." [PMID:10637607] +comment: See also the cellular component term 'SAGA complex ; GO:0000124'. +synonym: "PCAF histone acetylase-associated complex" EXACT [] +synonym: "SPT3-TAF9-PCAF acetylase complex" EXACT [GOC:rl, PMID:18838386] +is_a: GO:0070461 ! SAGA-type complex + +[Term] +id: GO:0000126 +name: transcription factor TFIIIB complex +namespace: cellular_component +def: "A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF." [GOC:mah, PMID:11433012] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex + +[Term] +id: GO:0000127 +name: transcription factor TFIIIC complex +namespace: cellular_component +def: "A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions." [GOC:mah, GOC:vw, PMID:11433012, PMID:16751097] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex + +[Term] +id: GO:0000128 +name: flocculation +namespace: biological_process +alt_id: GO:0000501 +alt_id: GO:0032128 +alt_id: GO:0043689 +alt_id: GO:0043690 +def: "The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs." [GOC:jl, GOC:vw, PMID:21114594, PMID:8740415] +comment: The word floc derives from the Latin word floccus, which means a tuft of wool. +subset: goslim_pir +synonym: "cell-cell adhesion involved in flocculation" EXACT [] +synonym: "cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction" NARROW [] +synonym: "flocculation via cell wall protein-carbohydrate interaction" RELATED [] +synonym: "flocculation via extracellular polymer" RELATED [] +xref: Wikipedia:Flocculation +is_a: GO:0051703 ! intraspecies interaction between organisms +is_a: GO:0098610 ! adhesion between unicellular organisms + +[Term] +id: GO:0000131 +name: incipient cellular bud site +namespace: cellular_component +def: "The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence." [GOC:clt] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0000132 +name: establishment of mitotic spindle orientation +namespace: biological_process +alt_id: GO:0030607 +alt_id: GO:0030609 +def: "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." [GOC:ems] +synonym: "establishment of spindle orientation during mitosis" RELATED [GOC:dph, GOC:tb] +synonym: "establishment of spindle orientation involved in mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "mitotic spindle orientation" EXACT [] +synonym: "orienting of mitotic spindle" EXACT [] +is_a: GO:0040001 ! establishment of mitotic spindle localization +is_a: GO:0051294 ! establishment of spindle orientation +intersection_of: GO:0051294 ! establishment of spindle orientation +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0000133 +name: polarisome +namespace: cellular_component +def: "Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p." [PMID:14734532, PMID:14998522, PMID:9632790] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005938 ! cell cortex +relationship: part_of GO:0030427 ! site of polarized growth + +[Term] +id: GO:0000136 +name: alpha-1,6-mannosyltransferase complex +namespace: cellular_component +def: "A large, multiprotein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins." [GOC:mcc, PMID:10037752, PMID:11095735, PMID:18083825] +is_a: GO:0031501 ! mannosyltransferase complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0000137 ! Golgi cis cisterna +relationship: part_of GO:0030173 ! integral component of Golgi membrane + +[Term] +id: GO:0000137 +name: Golgi cis cisterna +namespace: cellular_component +def: "The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER." [ISBN:0815316194] +is_a: GO:0031985 ! Golgi cisterna + +[Term] +id: GO:0000138 +name: Golgi trans cisterna +namespace: cellular_component +def: "The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed." [ISBN:0815316194] +synonym: "late Golgi" RELATED [GOC:mah] +is_a: GO:0031985 ! Golgi cisterna + +[Term] +id: GO:0000139 +name: Golgi membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0000140 +name: acylglycerone-phosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+)." [EC:1.1.1.101] +synonym: "1-acyldihydroxyacetone-phosphate reductase activity" EXACT [] +synonym: "1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.101] +synonym: "acyldihydroxyacetone phosphate reductase activity" EXACT [EC:1.1.1.101] +synonym: "palmitoyl dihydroxyacetone phosphate reductase activity" EXACT [EC:1.1.1.101] +synonym: "palmitoyl-dihydroxyacetone-phosphate reductase activity" EXACT [EC:1.1.1.101] +synonym: "palmitoyldihydroxyacetone-phosphate reductase activity" EXACT [EC:1.1.1.101] +xref: EC:1.1.1.101 +xref: MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN +xref: Reactome:R-HSA-75883 "O-hexadecylglycerone phosphate + NADPH + H+ => 1-hexadecyl glycerol-3-phosphate + NADP+" +xref: RHEA:17341 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0000142 +name: cellular bud neck contractile ring +namespace: cellular_component +def: "A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae." [GOC:krc, PMID:16009555] +synonym: "neck ring" EXACT [] +is_a: GO:0110085 ! mitotic actomyosin contractile ring +intersection_of: GO:0005826 ! actomyosin contractile ring +intersection_of: part_of GO:0005935 ! cellular bud neck +relationship: part_of GO:0005935 ! cellular bud neck + +[Term] +id: GO:0000144 +name: cellular bud neck septin ring +namespace: cellular_component +def: "A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange." [GOC:krc, PMID:16009555] +is_a: GO:0000399 ! cellular bud neck septin structure +is_a: GO:0005940 ! septin ring +is_a: GO:0032161 ! cleavage apparatus septin structure +intersection_of: GO:0005940 ! septin ring +intersection_of: part_of GO:0005935 ! cellular bud neck + +[Term] +id: GO:0000145 +name: exocyst +namespace: cellular_component +def: "A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals." [GOC:cilia, PMID:15292201, PMID:27243008, PMID:9700152] +synonym: "exocyst complex" EXACT [] +synonym: "Sec6/8 complex" EXACT [] +xref: Wikipedia:Exocyst +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0000146 +name: microfilament motor activity +namespace: molecular_function +def: "Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)." [GOC:mah, ISBN:0815316194] +synonym: "actin filament motor activity" EXACT [GOC:dph] +synonym: "actin-filament motor activity" EXACT [] +synonym: "muscle motor activity" NARROW [] +synonym: "myosin ATPase activity" RELATED [] +xref: Reactome:R-HSA-2316352 "SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane" +xref: Reactome:R-HSA-432237 "Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane" +xref: Reactome:R-HSA-9023171 "Insulin secretory granule translocates across the cortical actin network" +is_a: GO:0003774 ! motor activity + +[Term] +id: GO:0000147 +name: actin cortical patch assembly +namespace: biological_process +def: "Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells." [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0030866 ! cortical actin cytoskeleton organization +is_a: GO:0044396 ! actin cortical patch organization + +[Term] +id: GO:0000148 +name: 1,3-beta-D-glucan synthase complex +namespace: cellular_component +def: "A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain." [EC:2.4.1.34] +synonym: "(1->3)-beta-glucan synthase complex" EXACT [GOC:tb] +synonym: "1,3-beta-glucan synthase complex" EXACT [GOC:tb] +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0000149 +name: SNARE binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein." [PMID:12642621] +subset: goslim_chembl +synonym: "SNAP receptor binding" EXACT [] +xref: Reactome:R-HSA-210426 "Glutamate synaptic vesicle docking and priming" +xref: Reactome:R-HSA-210430 "release of L-Glutamate at the synapse" +xref: Reactome:R-HSA-265166 "Exocytosis of Insulin" +xref: Reactome:R-HSA-372505 "Acetylcholine synaptic vesicle docking and priming" +xref: Reactome:R-HSA-372529 "Release of acetylcholine at the synapse" +xref: Reactome:R-HSA-374899 "Release of noradrenaline at the synapse" +xref: Reactome:R-HSA-374922 "Noradrenalin synaptic vesicle docking and priming" +xref: Reactome:R-HSA-376357 "Vamp7 associated Lysosome to Plasma membrane transport" +xref: Reactome:R-HSA-376364 "Vamp8 associated secretory vesicle to plasma membrane transport" +xref: Reactome:R-HSA-376369 "Vamp2 associated secretory vesicle to plasma membrane transport" +xref: Reactome:R-HSA-380574 "Dopamine synaptic vesicle docking and priming" +xref: Reactome:R-HSA-380869 "Release of docked dopamine loaded synaptic vesicle" +xref: Reactome:R-HSA-380901 "Release of docked serotonin loaded synaptic vesicle" +xref: Reactome:R-HSA-380905 "Serotonin loaded synaptic vesicle docking and priming" +xref: Reactome:R-HSA-888589 "Release of GABA at the synapse" +xref: Reactome:R-HSA-9023173 "Insulin secretory granule docks at the plasma membrane" +xref: Reactome:R-HSA-917744 "GABA loaded synaptic vesicle Docking and Priming" +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0000150 +name: recombinase activity +namespace: molecular_function +def: "Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA." [GOC:elh] +comment: Note that this term represents activities that do not break or form phosphodiester bonds, and is therefore not a parent of 'site-specific recombinase activity ; GO:0009009'. +subset: goslim_metagenomics +synonym: "strand transferase" NARROW [] +xref: Reactome:R-HSA-912458 "Formation of meiotic heteroduplex" +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0006310 ! DNA recombination + +[Term] +id: GO:0000151 +name: ubiquitin ligase complex +namespace: cellular_component +def: "A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex." [GOC:jh2, PMID:9529603] +subset: goslim_pir +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000152 +name: nuclear ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex found in the nucleus." [GOC:mah] +is_a: GO:0000151 ! ubiquitin ligase complex +intersection_of: GO:0000151 ! ubiquitin ligase complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000153 +name: cytoplasmic ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex found in the cytoplasm." [GOC:mah] +is_a: GO:0000151 ! ubiquitin ligase complex +intersection_of: GO:0000151 ! ubiquitin ligase complex +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000154 +name: rRNA modification +namespace: biological_process +alt_id: GO:0016548 +def: "The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically." [GOC:curators] +comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'. +synonym: "rRNA editing" NARROW [GOC:hjd] +is_a: GO:0006364 ! rRNA processing +is_a: GO:0009451 ! RNA modification + +[Term] +id: GO:0000155 +name: phosphorelay sensor kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response." [GOC:bf, GOC:mcc, PMID:10966457, PMID:20223701, PMID:9191038] +synonym: "two-component sensor activity" NARROW [] +synonym: "two-component sensor molecule" NARROW [] +synonym: "two-component system sensor activity" NARROW [] +xref: EC:2.7.3 +is_a: GO:0004673 ! protein histidine kinase activity +is_a: GO:0140299 ! small molecule sensor activity +relationship: part_of GO:0000160 ! phosphorelay signal transduction system +relationship: part_of GO:0023014 ! signal transduction by protein phosphorylation + +[Term] +id: GO:0000156 +name: phosphorelay response regulator activity +namespace: molecular_function +def: "Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response." [GOC:bf, PMID:10966457, PMID:11842140] +synonym: "two-component response regulator activity" NARROW [] +is_a: GO:0060089 ! molecular transducer activity +relationship: part_of GO:0000160 ! phosphorelay signal transduction system +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15611 xsd:anyURI + +[Term] +id: GO:0000159 +name: protein phosphatase type 2A complex +namespace: cellular_component +def: "A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit." [GOC:mah, ISBN:0198547684, PMID:17245430] +synonym: "protein phosphatase 2 complex" RELATED [GOC:dph, GOC:rl] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000160 +name: phosphorelay signal transduction system +namespace: biological_process +def: "A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins." [PMID:9191038] +subset: goslim_metagenomics +synonym: "histidyl-aspartyl phosphorelay" EXACT [] +synonym: "phosphorelay signal transduction system" NARROW [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0000161 +name: osmosensory signaling MAPK cascade +namespace: biological_process +def: "A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K." [PMID:17604854, PMID:9561267] +synonym: "High Osmolarity Glycerol (HOG) MAPK pathway" NARROW [PMID:20880736] +synonym: "Hog1 MAPK pathway" NARROW [PMID:20880736] +synonym: "Hog1/Sty1 stress-activated MAPK cascade" NARROW [] +synonym: "MAPK cascade involved in osmosensory signaling pathway" EXACT [] +synonym: "MAPKKK cascade during osmolarity sensing" EXACT [] +synonym: "MAPKKK cascade involved in osmosensory signaling pathway" EXACT [GOC:signaling] +synonym: "MAPKKK cascade involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "osmolarity sensing, MAPKKK cascade" EXACT [] +is_a: GO:0051403 ! stress-activated MAPK cascade + +[Term] +id: GO:0000162 +name: tryptophan biosynthetic process +namespace: biological_process +alt_id: GO:0009096 +def: "The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate." [GOC:mah, ISBN:0471331309, MetaCyc:TRPSYN-PWY] +synonym: "aromatic amino acid family biosynthetic process, anthranilate pathway" EXACT [] +synonym: "tryptophan anabolism" EXACT [] +synonym: "tryptophan biosynthesis" EXACT [] +synonym: "tryptophan formation" EXACT [] +synonym: "tryptophan synthesis" EXACT [] +xref: MetaCyc:TRPSYN-PWY +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0009073 ! aromatic amino acid family biosynthetic process +is_a: GO:0046219 ! indolalkylamine biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0000164 +name: protein phosphatase type 1 complex +namespace: cellular_component +def: "A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity." [GOC:mah, GOC:ssd] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000165 +name: MAPK cascade +namespace: biological_process +def: "An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:mtg_signaling_feb11, PMID:20811974, PMID:9561267] +comment: MAPK cascades lie downstream of many cell surface receptors and cooperate in transmitting various extracellular signals to the nucleus. One way by which the specificity of each cascade is regulated is through the existence of several distinct components in each tier of the different cascades. The cascades are typically named according to the component in the MAPK tier. +synonym: "ERK/MAPK cascade" NARROW [] +synonym: "MAP kinase cascade" EXACT [] +synonym: "MAP kinase kinase kinase cascade" EXACT [] +synonym: "MAPK signal transduction" EXACT [GOC:signaling] +synonym: "MAPK signaling" RELATED [] +synonym: "MAPK signalling" RELATED [] +synonym: "MAPKKK cascade" EXACT [] +synonym: "MAPKKK cascade during sporulation" NARROW [] +synonym: "mitogen-activated protein kinase cascade" EXACT [GOC:bf] +xref: Wikipedia:MAPK_cascade +xref: Wikipedia:Mitogen-activated_protein_kinase +is_a: GO:0023014 ! signal transduction by protein phosphorylation +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0000166 +name: nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684] +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +is_a: GO:0036094 ! small molecule binding +is_a: GO:1901265 ! nucleoside phosphate binding + +[Term] +id: GO:0000167 +name: activation of MAPKKK activity involved in osmosensory signaling pathway +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing." [PMID:9561267] +synonym: "activation of MAP kinase kinase kinase activity during osmolarity sensing" EXACT [] +synonym: "activation of MAPKKK activity during osmolarity sensing" EXACT [] +synonym: "activation of MAPKKK activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "osmolarity sensing, activation of MAP kinase kinase kinase activity" EXACT [] +synonym: "osmolarity sensing, activation of MAPKKK activity" EXACT [] +is_a: GO:0000185 ! activation of MAPKKK activity +relationship: part_of GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0000168 +name: activation of MAPKK activity involved in osmosensory signaling pathway +namespace: biological_process +alt_id: GO:0007233 +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing." [PMID:9561267] +synonym: "activation of MAP kinase kinase activity during osmolarity sensing" EXACT [] +synonym: "activation of MAPKK activity during osmolarity sensing" EXACT [] +synonym: "activation of MAPKK activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "activation of Pbs2 kinase" NARROW [] +synonym: "osmolarity sensing, activation of MAP kinase kinase activity" EXACT [] +synonym: "osmolarity sensing, activation of MAPKK activity" EXACT [] +is_a: GO:0000186 ! activation of MAPKK activity +relationship: part_of GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0000169 +name: activation of MAPK activity involved in osmosensory signaling pathway +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing." [PMID:9561267] +synonym: "activation of MAPK activity during osmolarity sensing" EXACT [] +synonym: "activation of MAPK activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "osmolarity sensing, activation of MAPK activity" EXACT [] +is_a: GO:0000187 ! activation of MAPK activity +relationship: part_of GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0000170 +name: sphingosine hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of sphingolipid long chain bases." [PMID:9556590] +xref: Reactome:R-HSA-428260 "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0000171 +name: ribonuclease MRP activity +namespace: molecular_function +def: "Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA." [PMID:17881380] +synonym: "RNase MRP" EXACT [] +xref: Wikipedia:RNase_MRP +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0000172 +name: ribonuclease MRP complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication." [GOC:sgd_curators, PMID:10690410, PMID:14729943, PMID:7510714] +synonym: "ribonuclease mitochondrial RNA processing complex" EXACT [] +synonym: "RNase MRP complex" EXACT [] +is_a: GO:0005732 ! small nucleolar ribonucleoprotein complex +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0000173 +name: inactivation of MAPK activity involved in osmosensory signaling pathway +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing." [PMID:9561267] +synonym: "inactivation of MAPK activity during osmolarity sensing" EXACT [] +synonym: "inactivation of MAPK activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "osmolarity sensing, inactivation of MAPK" EXACT [] +synonym: "osmolarity sensing, termination of MAPK activity" EXACT [] +synonym: "termination of MAPK activity during osmolarity sensing" EXACT [] +is_a: GO:0000188 ! inactivation of MAPK activity +relationship: part_of GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0000174 +name: obsolete inactivation of MAPK (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "inactivation of MAPK (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0000175 +name: 3'-5'-exoribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] +synonym: "3'-5' exoribonuclease activity" EXACT [] +xref: EC:3.1.13 +xref: Reactome:R-HSA-430028 "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion" +xref: Reactome:R-HSA-6791218 "12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA" +xref: Reactome:R-HSA-6791222 "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA" +xref: Reactome:R-HSA-6791227 "47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA" +is_a: GO:0008408 ! 3'-5' exonuclease activity +is_a: GO:0016896 ! exoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0000176 +name: nuclear exosome (RNase complex) +namespace: cellular_component +def: "A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured." [PMID:17174896, PMID:20531386, PMID:26726035] +synonym: "eukaryotic exosome multienzyme ribonuclease complex" EXACT [] +synonym: "nuclear exosome (ribonuclease complex)" EXACT [] +synonym: "nuclear exosome multienzyme ribonuclease complex" EXACT [] +is_a: GO:0000178 ! exosome (RNase complex) +intersection_of: GO:0000178 ! exosome (RNase complex) +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0000177 +name: cytoplasmic exosome (RNase complex) +namespace: cellular_component +def: "A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured." [PMID:17174896, PMID:20531386, PMID:26726035] +synonym: "cytoplasmic exosome (ribonuclease complex)" EXACT [] +synonym: "cytoplasmic exosome multienzyme ribonuclease complex" EXACT [] +synonym: "prokaryotic exosome multienzyme ribonuclease complex" EXACT [] +is_a: GO:0000178 ! exosome (RNase complex) +intersection_of: GO:0000178 ! exosome (RNase complex) +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000178 +name: exosome (RNase complex) +namespace: cellular_component +def: "A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured." [PMID:17174896, PMID:20531386, PMID:26726035] +comment: Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies. +subset: goslim_pir +synonym: "exosome (ribonucleasease complex)" EXACT [] +synonym: "exosome multienzyme ribonuclease complex" EXACT [] +is_a: GO:1905354 ! exoribonuclease complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000179 +name: rRNA (adenine-N6,N6-)-dimethyltransferase activity +namespace: molecular_function +alt_id: GO:0043790 +def: "Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor." [ISBN:1555811337, PMID:10690410] +synonym: "18S rRNA dimethylase activity" EXACT [] +synonym: "dimethyladenosine transferase activity" EXACT [] +synonym: "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity" EXACT [] +xref: Reactome:R-HSA-6790994 "DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851" +xref: Reactome:R-HSA-6793066 "TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity + +[Term] +id: GO:0000180 +name: obsolete cytosolic large ribosomal subunit +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because more specific children exist. +synonym: "cytosolic large ribosomal subunit" EXACT [] +is_obsolete: true +consider: GO:0022625 + +[Term] +id: GO:0000181 +name: obsolete cytosolic small ribosomal subunit +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because more specific children exist. +synonym: "cytosolic small ribosomal subunit" EXACT [] +is_obsolete: true +consider: GO:0022627 + +[Term] +id: GO:0000182 +name: rDNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA." [GOC:mah] +synonym: "ribosomal DNA binding" EXACT [] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0000183 +name: rDNA heterochromatin assembly +namespace: biological_process +def: "The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA." [PMID:10219245] +synonym: "chromatin silencing at rDNA" RELATED [] +synonym: "chromatin silencing at ribosomal DNA" BROAD [] +synonym: "heterochromatic silencing at rDNA" BROAD [] +synonym: "rDNA chromatin silencing" BROAD [GOC:mah] +is_a: GO:0031507 ! heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19238 xsd:anyURI + +[Term] +id: GO:0000184 +name: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +namespace: biological_process +def: "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." [GOC:krc, GOC:ma, PMID:10025395] +synonym: "mRNA breakdown, nonsense-mediated decay" EXACT [] +synonym: "mRNA catabolic process, nonsense-mediated" EXACT [] +synonym: "mRNA catabolism, nonsense-mediated" EXACT [] +synonym: "mRNA degradation, nonsense-mediated decay" EXACT [] +synonym: "nonsense-mediated mRNA decay" EXACT [] +synonym: "nuclear mRNA catabolic process, nonsense-mediated decay" EXACT [] +xref: Wikipedia:Nonsense-mediated_decay +xref: Wikipedia:Nonsense-mediated_mRNA_decay +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0000185 +name: activation of MAPKKK activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK)." [PMID:9561267] +synonym: "activation of MAP kinase kinase kinase" EXACT [] +synonym: "activation of MAP3K activity" EXACT [GOC:bf] +synonym: "activation of MAPKKK activity during sporulation" NARROW [] +synonym: "positive regulation of MAP kinase kinase kinase activity" BROAD [] +synonym: "positive regulation of MAPKKK activity" BROAD [] +is_a: GO:0032147 ! activation of protein kinase activity +is_a: GO:0043406 ! positive regulation of MAP kinase activity +relationship: positively_regulates GO:0004709 ! MAP kinase kinase kinase activity + +[Term] +id: GO:0000186 +name: activation of MAPKK activity +namespace: biological_process +alt_id: GO:0007255 +def: "The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK)." [PMID:9561267] +synonym: "activation of MAP kinase kinase activity" EXACT [] +synonym: "activation of MAP/ERK kinase kinase" EXACT [] +synonym: "activation of MAP2K activity" EXACT [GOC:bf] +synonym: "activation of MAPKK activity during sporulation" NARROW [] +synonym: "positive regulation of MAPKK activity" BROAD [] +is_a: GO:0032147 ! activation of protein kinase activity +is_a: GO:0043406 ! positive regulation of MAP kinase activity +relationship: positively_regulates GO:0004708 ! MAP kinase kinase activity + +[Term] +id: GO:0000187 +name: activation of MAPK activity +namespace: biological_process +def: "The initiation of the activity of the inactive enzyme MAP kinase (MAPK)." [PMID:9561267] +synonym: "activation of MAP kinase" EXACT [] +synonym: "activation of MAPK activity during sporulation" NARROW [] +synonym: "MAPK activation" EXACT [] +is_a: GO:0032147 ! activation of protein kinase activity +is_a: GO:0043406 ! positive regulation of MAP kinase activity + +[Term] +id: GO:0000188 +name: inactivation of MAPK activity +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase." [PMID:9561267] +synonym: "inactivation of MAPK during sporulation" NARROW [] +synonym: "termination of MAPK activity" EXACT [] +is_a: GO:0043407 ! negative regulation of MAP kinase activity + +[Term] +id: GO:0000189 +name: obsolete MAPK import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation." [PMID:9561267] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "nuclear translocation of MAPK" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0000190 +name: obsolete MAPKKK cascade (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "MAPKKK cascade (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000191 +name: obsolete activation of MAPKKK (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKKK (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000192 +name: obsolete activation of MAPKK (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKK (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000193 +name: obsolete activation of MAPK (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPK (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000194 +name: obsolete inactivation of MAPK (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "inactivation of MAPK (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000195 +name: obsolete nuclear translocation of MAPK (pseudohyphal growth) +namespace: biological_process +def: "OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "nuclear translocation of MAPK (pseudohyphal growth)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000196 +name: cell wall integrity MAPK cascade +namespace: biological_process +def: "A MAPK cascade that contributes to cell wall organization or biogenesis." [PMID:17604854, PMID:9561267] +synonym: "cell integrity MAPK pathway" EXACT [GOC:vw, PMID:23934882] +synonym: "cell wall biogenesis, MAPKKK cascade" EXACT [] +synonym: "MAPK cascade involved in cell wall biogenesis" NARROW [GOC:vw] +synonym: "MAPK cascade involved in cell wall organization or biogenesis" EXACT [] +synonym: "MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:signaling] +synonym: "Mpk1 cascade" NARROW [PMID:10523653] +synonym: "Pmk1 MAPK cell integrity signaling" NARROW [PMID:20032302] +synonym: "Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [PMID:23934882] +synonym: "PMK1-MAPK signal transduction pathway" NARROW [PMID:23454094] +synonym: "Slt2 cascade" NARROW [PMID:10523653] +is_a: GO:0051403 ! stress-activated MAPK cascade +intersection_of: GO:0051403 ! stress-activated MAPK cascade +intersection_of: part_of GO:0071554 ! cell wall organization or biogenesis +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0000197 +name: activation of MAPKKK activity involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis." [PMID:9561267] +synonym: "activation of MAP kinase kinase kinase activity during cell wall biogenesis" EXACT [] +synonym: "activation of MAPKKK activity involved in cell wall biogenesis" RELATED [] +synonym: "activation of MAPKKK activity involved in cell wall integrity" EXACT [GOC:dgf] +synonym: "cell wall biogenesis, activation of MAP kinase kinase kinase activity" EXACT [] +synonym: "cell wall biogenesis, activation of MAPKKK activity" EXACT [] +is_a: GO:0000185 ! activation of MAPKKK activity +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0000198 +name: activation of MAPKK activity involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis." [PMID:9561267] +synonym: "activation of MAP kinase kinase activity during cell wall biogenesis" EXACT [] +synonym: "activation of MAPKK activity involved in cell wall biogenesis" RELATED [] +synonym: "activation of MAPKK activity involved in cell wall integrity" EXACT [GOC:dgf] +synonym: "cell wall biogenesis, activation of MAP kinase kinase activity" EXACT [] +synonym: "cell wall biogenesis, activation of MAPKK activity" EXACT [] +is_a: GO:0000186 ! activation of MAPKK activity +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0000199 +name: activation of MAPK activity involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] +synonym: "activation of MAPK activity involved in cell wall biogenesis" NARROW [] +synonym: "activation of MAPK activity involved in cell wall integrity" EXACT [GOC:dgf] +synonym: "cell wall biogenesis, activation of MAPK activity" EXACT [] +is_a: GO:0000187 ! activation of MAPK activity +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0000200 +name: inactivation of MAPK activity involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis." [PMID:9561267] +synonym: "cell wall biogenesis, inactivation of MAPK activity" EXACT [] +synonym: "cell wall biogenesis, termination of MAPK activity" EXACT [] +synonym: "inactivation of MAPK activity involved in cell wall integrity" EXACT [GOC:dgf] +synonym: "inactivation of MAPK activity involved in cell wall organization or biogenesis" RELATED [] +synonym: "termination of MAPK activity during cell wall biogenesis" EXACT [] +is_a: GO:0000188 ! inactivation of MAPK activity +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0000201 +name: obsolete MAPK import into nucleus involved in cell wall organization or biogenesis +namespace: biological_process +def: "OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis." [PMID:9561267] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "cell wall biogenesis, MAPK import into nucleus" EXACT [GOC:mah] +synonym: "cell wall biogenesis, nuclear translocation of MAPK" NARROW [GOC:mah] +synonym: "MAPK import into nucleus involved in cell wall biogenesis" NARROW [GOC:vw] +synonym: "MAPK import into nucleus involved in cell wall integrity" EXACT [GOC:dgf, GOC:mah] +synonym: "nuclear translocation of MAPK involved in cell wall biogenesis" NARROW [GOC:mah] +synonym: "nuclear translocation of MAPK involved in cell wall integrity" NARROW [GOC:dgf, GOC:mah] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0000202 +name: obsolete MAPKKK cascade during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "MAPKKK cascade during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000203 +name: obsolete activation of MAPKKK during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKKK during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000204 +name: obsolete activation of MAPKK during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKK during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000205 +name: obsolete activation of MAPK during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPK during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000206 +name: obsolete inactivation of MAPK during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "inactivation of MAPK during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000207 +name: obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "nuclear translocation of MAPK during sporulation (sensu Saccharomyces)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000208 +name: obsolete MAPK import into nucleus involved in osmosensory signaling pathway +namespace: biological_process +def: "OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing." [PMID:9561267] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "MAPK import into nucleus during osmolarity sensing" EXACT [GOC:mah] +synonym: "MAPK import into nucleus involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "nuclear translocation of MAPK during osmolarity sensing" EXACT [] +synonym: "nuclear translocation of MAPK involved in osmosensory signaling pathway" NARROW [GOC:mah] +synonym: "nuclear translocation of MAPK involved in osmosensory signalling pathway" NARROW [GOC:mah] +synonym: "osmolarity sensing, MAPK import into nucleus" EXACT [GOC:mah] +synonym: "osmolarity sensing, nuclear translocation of MAPK" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0000209 +name: protein polyubiquitination +namespace: biological_process +def: "Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain." [ISBN:0815316194] +synonym: "polyubiquitin" RELATED [] +synonym: "protein polyubiquitinylation" EXACT [] +synonym: "protein polyubiquitylation" EXACT [] +is_a: GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0000210 +name: NAD+ diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + H2O = AMP + NMN." [EC:3.6.1.22] +synonym: "NAD diphosphatase activity" EXACT [] +synonym: "NAD pyrophosphatase activity" EXACT [] +synonym: "NAD(+) pyrophosphatase activity" EXACT [EC:3.6.1.22] +synonym: "NAD+ phosphohydrolase activity" EXACT [EC:3.6.1.22] +synonym: "NAD+ pyrophosphatase activity" EXACT [EC:3.6.1.22] +synonym: "NADH pyrophosphatase activity" BROAD [EC:3.6.1.22] +synonym: "NADP pyrophosphatase activity" BROAD [EC:3.6.1.22] +synonym: "nicotinamide adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.22] +xref: EC:3.6.1.22 +xref: MetaCyc:NADPYROPHOSPHAT-RXN +xref: RHEA:11800 +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0000211 +name: obsolete protein degradation tagging activity +namespace: molecular_function +def: "OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction." [GOC:cl, ISBN:0815316194] +comment: This term was made obsolete because it represents a biological process and a molecular function. +synonym: "protein degradation tagging activity" EXACT [] +is_obsolete: true +consider: GO:0005515 +consider: GO:0019941 + +[Term] +id: GO:0000212 +name: meiotic spindle organization +namespace: biological_process +alt_id: GO:0043147 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." [GOC:go_curators, GOC:mah] +synonym: "meiotic spindle organisation" EXACT [] +synonym: "meiotic spindle organization and biogenesis" RELATED [GOC:mah] +synonym: "meiotic spindle stabilization" RELATED [] +synonym: "spindle organization during meiosis" EXACT [GOC:mah] +is_a: GO:0007051 ! spindle organization +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0007051 ! spindle organization +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0000213 +name: tRNA-intron endonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron." [EC:3.1.27.9] +synonym: "splicing endonuclease activity" EXACT [EC:3.1.27.9] +synonym: "transfer ribonucleate intron endoribonuclease activity" EXACT [EC:3.1.27.9] +synonym: "transfer splicing endonuclease activity" EXACT [EC:3.1.27.9] +synonym: "tRNA splicing endonuclease activity" EXACT [EC:3.1.27.9] +synonym: "tRNA-intron endoribonuclease activity" EXACT [] +synonym: "tRNA-splicing endonuclease activity" EXACT [EC:3.1.27.9] +synonym: "tRNATRPintron endonuclease activity" EXACT [EC:3.1.27.9] +xref: EC:3.1.27.9 +xref: MetaCyc:3.1.27.9-RXN +is_a: GO:0004549 ! tRNA-specific ribonuclease activity +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0000214 +name: tRNA-intron endonuclease complex +namespace: cellular_component +def: "A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron." [PMID:22391451] +synonym: "SEN complex" EXACT [GOC:se, PMID:22391451] +synonym: "tRNA splicing endonuclease complex" EXACT [GOC:se, PMID:22391451] +is_a: GO:1902555 ! endoribonuclease complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000215 +name: tRNA 2'-phosphotransferase activity +namespace: molecular_function +alt_id: GO:0008665 +def: "Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate." [EC:2.7.1.160, PMID:9148937] +subset: goslim_chembl +synonym: "2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity" EXACT [EC:2.7.1.160] +synonym: "2'-phospho-tRNA:NAD+ phosphotransferase activity" EXACT [EC:2.7.1.160] +synonym: "2'-phosphotransferase activity" BROAD [] +synonym: "Tpt1" RELATED [EC:2.7.1.160] +synonym: "Tpt1p" RELATED [EC:2.7.1.160] +synonym: "yeast 2'-phosphotransferase activity" NARROW [EC:2.7.1.160] +xref: EC:2.7.1.160 +xref: MetaCyc:2.7.1.160-RXN +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0000216 +name: obsolete M/G1 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle." [GOC:mah, GOC:mtg_cell_cycle] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "M/G1 transition of mitotic cell cycle" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000217 +name: DNA secondary structure binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions." [GOC:krc] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0000219 +name: obsolete vacuolar hydrogen-transporting ATPase +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "V-ATPase" EXACT [] +synonym: "vacuolar hydrogen-transporting ATPase" EXACT [] +is_obsolete: true +consider: GO:0016469 + +[Term] +id: GO:0000220 +name: vacuolar proton-transporting V-type ATPase, V0 domain +namespace: cellular_component +def: "The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane." [GOC:mah, PMID:16449553] +comment: Note that this domain often consists of five subunits, although in some mammalian tissues it may have an additional subunit. +synonym: "vacuolar hydrogen ion-transporting ATPase V0 domain" EXACT [] +is_a: GO:0033179 ! proton-transporting V-type ATPase, V0 domain +intersection_of: GO:0033179 ! proton-transporting V-type ATPase, V0 domain +intersection_of: part_of GO:0005773 ! vacuole +relationship: part_of GO:0005773 ! vacuole + +[Term] +id: GO:0000221 +name: vacuolar proton-transporting V-type ATPase, V1 domain +namespace: cellular_component +def: "The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane." [GOC:mah, PMID:16449553] +comment: Note that this domain generally consists of eight subunits. +synonym: "vacuolar hydrogen ion-transporting ATPase V1 domain" EXACT [] +is_a: GO:0033180 ! proton-transporting V-type ATPase, V1 domain +intersection_of: GO:0033180 ! proton-transporting V-type ATPase, V1 domain +intersection_of: part_of GO:0005773 ! vacuole +relationship: part_of GO:0016471 ! vacuolar proton-transporting V-type ATPase complex + +[Term] +id: GO:0000222 +name: plasma membrane proton-transporting V-type ATPase, V0 domain +namespace: cellular_component +def: "The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane." [GOC:mah] +synonym: "plasma membrane hydrogen ion-transporting ATPase V0 domain" EXACT [] +is_a: GO:0033179 ! proton-transporting V-type ATPase, V0 domain +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0033179 ! proton-transporting V-type ATPase, V0 domain +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0033181 ! plasma membrane proton-transporting V-type ATPase complex + +[Term] +id: GO:0000223 +name: plasma membrane proton-transporting V-type ATPase, V1 domain +namespace: cellular_component +def: "The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane." [GOC:mah] +synonym: "plasma membrane hydrogen ion-transporting ATPase V1 domain" EXACT [] +is_a: GO:0033180 ! proton-transporting V-type ATPase, V1 domain +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0033180 ! proton-transporting V-type ATPase, V1 domain +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0033181 ! plasma membrane proton-transporting V-type ATPase complex + +[Term] +id: GO:0000224 +name: peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue." [EC:3.5.1.52] +synonym: "glycopeptidase activity" BROAD [EC:3.5.1.52] +synonym: "glycopeptide N-glycosidase activity" BROAD [EC:3.5.1.52] +synonym: "jack-bean glycopeptidase" NARROW [EC:3.5.1.52] +synonym: "N-glycanase activity" RELATED [EC:3.5.1.52] +synonym: "N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.52] +synonym: "N-oligosaccharide glycopeptidase activity" RELATED [EC:3.5.1.52] +synonym: "peptide:N-glycanase" RELATED [] +synonym: "PNGase" EXACT [] +synonym: "PNGase A" RELATED [EC:3.5.1.52] +synonym: "PNGase F" RELATED [EC:3.5.1.52] +xref: EC:3.5.1.52 +xref: MetaCyc:3.5.1.52-RXN +xref: Reactome:R-HSA-8850594 "Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins" +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0000225 +name: N-acetylglucosaminylphosphatidylinositol deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane." [EC:3.5.1.89] +comment: Note that this function was formerly EC:3.1.1.69. +synonym: "6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity" EXACT [EC:3.5.1.89] +synonym: "acetylglucosaminylphosphatidylinositol deacetylase activity" EXACT [EC:3.5.1.89] +synonym: "GlcNAc-PI de-N-acetylase activity" EXACT [EC:3.5.1.89] +synonym: "GlcNAc-PI deacetylase activity" EXACT [EC:3.5.1.89] +synonym: "N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity" EXACT [EC:3.5.1.89] +synonym: "N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity" EXACT [EC:3.5.1.89] +xref: EC:3.5.1.89 +xref: MetaCyc:3.1.1.69-RXN +xref: Reactome:R-HSA-162857 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate" +xref: RHEA:11660 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0000226 +name: microtubule cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] +subset: goslim_drosophila +subset: goslim_pombe +synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah] +synonym: "microtubule cytoskeleton organization and biogenesis" RELATED [GOC:mah] +synonym: "microtubule dynamics" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007010 ! cytoskeleton organization +is_a: GO:0007017 ! microtubule-based process + +[Term] +id: GO:0000227 +name: oxaloacetate secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "oxaloacetate carrier activity" RELATED [] +is_a: GO:0015131 ! oxaloacetate transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0000228 +name: nuclear chromosome +namespace: cellular_component +def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "nuclear interphase chromosome" NARROW [] +is_a: GO:0005694 ! chromosome +intersection_of: GO:0005694 ! chromosome +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0000229 +name: cytoplasmic chromosome +namespace: cellular_component +def: "A chromosome found in the cytoplasm." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "cytoplasmic interphase chromosome" NARROW [] +is_a: GO:0005694 ! chromosome +intersection_of: GO:0005694 ! chromosome +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000230 +name: obsolete nuclear mitotic chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the nucleus during mitosis." [GOC:mah] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "nuclear mitotic chromosome" EXACT [] +is_obsolete: true +consider: GO:0000794 + +[Term] +id: GO:0000231 +name: obsolete cytoplasmic mitotic chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the cytoplasm during mitosis." [GOC:mah] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "cytoplasmic mitotic chromosome" EXACT [] +is_obsolete: true +consider: GO:0000793 + +[Term] +id: GO:0000232 +name: obsolete nuclear interphase chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the nucleus during interphase." [GOC:mah] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "nuclear interphase chromosome" EXACT [] +is_obsolete: true +consider: GO:0000228 + +[Term] +id: GO:0000233 +name: obsolete cytoplasmic interphase chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the cytoplasm during interphase." [GOC:mah] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "cytoplasmic interphase chromosome" EXACT [] +is_obsolete: true +consider: GO:0000229 + +[Term] +id: GO:0000234 +name: phosphoethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate." [EC:2.1.1.103] +synonym: "phosphoethanolamine methyltransferase activity" EXACT [EC:2.1.1.103] +synonym: "S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity" EXACT [EC:2.1.1.103] +xref: EC:2.1.1.103 +xref: KEGG_REACTION:R02037 +xref: MetaCyc:2.1.1.103-RXN +xref: RHEA:20365 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0000235 +name: astral microtubule +namespace: cellular_component +def: "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [ISBN:0815316194] +is_a: GO:0005876 ! spindle microtubule +is_a: GO:0005881 ! cytoplasmic microtubule +intersection_of: GO:0005876 ! spindle microtubule +intersection_of: part_of GO:0005818 ! aster +relationship: part_of GO:0005818 ! aster + +[Term] +id: GO:0000236 +name: mitotic prometaphase +namespace: biological_process +def: "The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0098763 ! mitotic cell cycle phase + +[Term] +id: GO:0000237 +name: leptotene +namespace: biological_process +def: "The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Leptotene +xref: Wikipedia:Meiosis#Leptotene +is_a: GO:0098764 ! meiosis I cell cycle phase +relationship: part_of GO:0007128 ! meiotic prophase I + +[Term] +id: GO:0000238 +name: zygotene +namespace: biological_process +def: "The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Meiosis#Zygotene +xref: Wikipedia:Zygotene +is_a: GO:0098764 ! meiosis I cell cycle phase +relationship: part_of GO:0007128 ! meiotic prophase I + +[Term] +id: GO:0000239 +name: pachytene +namespace: biological_process +def: "The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Meiosis#Pachytene +xref: Wikipedia:Pachytene +is_a: GO:0098764 ! meiosis I cell cycle phase +relationship: part_of GO:0007128 ! meiotic prophase I + +[Term] +id: GO:0000240 +name: diplotene +namespace: biological_process +def: "The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Diplotene +xref: Wikipedia:Meiosis#Diplotene +is_a: GO:0098764 ! meiosis I cell cycle phase +relationship: part_of GO:0007128 ! meiotic prophase I + +[Term] +id: GO:0000241 +name: diakinesis +namespace: biological_process +def: "The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Diakinesis +xref: Wikipedia:Meiosis#Diakinesis +is_a: GO:0098764 ! meiosis I cell cycle phase +relationship: part_of GO:0007128 ! meiotic prophase I + +[Term] +id: GO:0000242 +name: pericentriolar material +namespace: cellular_component +def: "A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome." [GOC:clt, ISBN:0815316194] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005813 ! centrosome + +[Term] +id: GO:0000243 +name: commitment complex +namespace: cellular_component +def: "A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript." [GOC:krc, ISBN:0879695897, PMID:9150140] +synonym: "mammalian spliceosomal complex E" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "mammalian spliceosomal E complex" NARROW [GOC:mah] +synonym: "yeast spliceosomal complex CC" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +relationship: has_part GO:0005685 ! U1 snRNP + +[Term] +id: GO:0000244 +name: spliceosomal tri-snRNP complex assembly +namespace: biological_process +alt_id: GO:0000351 +alt_id: GO:0000355 +def: "The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex." [ISBN:0879695897, PMID:9452384] +synonym: "assembly of spliceosomal tri-snRNP" EXACT [] +synonym: "assembly of spliceosomal tri-snRNP U4/U6.U5" NARROW [] +synonym: "assembly of spliceosomal tri-snRNP U4atac/U6atac.U5" NARROW [] +synonym: "snRNP recycling" BROAD [] +synonym: "spliceosomal tri-snRNP assembly" EXACT [] +synonym: "spliceosomal tri-snRNP U4/U6.U5 assembly" NARROW [] +synonym: "spliceosomal tri-snRNP U4atac/U6atac.U5 assembly" NARROW [] +is_a: GO:0000387 ! spliceosomal snRNP assembly + +[Term] +id: GO:0000245 +name: spliceosomal complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions." [PMID:9476892] +synonym: "spliceosome assembly" BROAD [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000246 +name: delta24(24-1) sterol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH." [EC:1.3.1.71, RHEA:18501] +synonym: "C-24(28) sterol reductase activity" EXACT [EC:1.3.1.71] +synonym: "D24(24-1)-sterol reductase activity" EXACT [] +synonym: "delta24(241)-sterol reductase activity" EXACT [EC:1.3.1.71] +synonym: "ergosterol:NADP+ delta24(241)-oxidoreductase activity" EXACT [EC:1.3.1.71] +synonym: "sterol Delta(24(28))-methylene reductase activity" EXACT [EC:1.3.1.71] +synonym: "sterol Delta(24(28))-reductase activity" EXACT [EC:1.3.1.71] +synonym: "sterol delta-24(28) methylene reductase activity" EXACT [] +synonym: "sterol delta-24(28) reductase activity" EXACT [] +synonym: "sterol delta24(28)-methylene reductase activity" EXACT [EC:1.3.1.71] +synonym: "sterol delta24(28)-reductase activity" EXACT [EC:1.3.1.71] +xref: EC:1.3.1.71 +xref: KEGG_REACTION:R05641 +xref: MetaCyc:1.3.1.71-RXN +xref: RHEA:18501 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0000247 +name: C-8 sterol isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols." [MetaCyc:RXN3O-203, PMID:8988026] +synonym: "delta-8-delta-7 sterol isomerase activity" EXACT [] +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0000248 +name: C-5 sterol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+." [MetaCyc:RXN3O-227] +synonym: "sterol-C5-desaturase activity" EXACT [] +xref: Reactome:R-HSA-195664 "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol" +xref: Reactome:R-HSA-6807053 "SC5D desaturates LTHSOL to 7-dehydroCHOL" +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water +is_a: GO:0070704 ! sterol desaturase activity + +[Term] +id: GO:0000249 +name: C-22 sterol desaturase activity +namespace: molecular_function +def: "Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+." [MetaCyc:RXN3O-227] +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water +is_a: GO:0070704 ! sterol desaturase activity + +[Term] +id: GO:0000250 +name: lanosterol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus." [EC:5.4.99.7, RHEA:14621] +synonym: "(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)" EXACT [EC:5.4.99.7] +synonym: "2,3-epoxysqualene lanosterol cyclase activity" EXACT [EC:5.4.99.7] +synonym: "2,3-epoxysqualene--lanosterol cyclase activity" EXACT [EC:5.4.99.7] +synonym: "2,3-epoxysqualene-lanosterol cyclase activity" EXACT [] +synonym: "2,3-oxidosqualene sterol cyclase activity" BROAD [EC:5.4.99.7] +synonym: "2,3-oxidosqualene-lanosterol cyclase activity" EXACT [EC:5.4.99.7] +synonym: "lanosterol 2,3-oxidosqualene cyclase activity" EXACT [EC:5.4.99.7] +synonym: "OSC" EXACT [] +synonym: "oxidosqualene--lanosterol cyclase activity" EXACT [EC:5.4.99.7] +synonym: "oxidosqualene-lanosterol cyclase activity" EXACT [] +synonym: "oxidosqualene:lanosterol cyclase activity" EXACT [PMID:18033581] +synonym: "squalene 2,3-epoxide:lanosterol cyclase activity" EXACT [EC:5.4.99.7] +synonym: "squalene epoxidase-cyclase activity" BROAD [EC:5.4.99.7] +synonym: "squalene-2,3-oxide-lanosterol cyclase activity" EXACT [EC:5.4.99.7] +xref: EC:5.4.99.7 +xref: KEGG_REACTION:R03199 +xref: MetaCyc:LANOSTEROL-SYNTHASE-RXN +xref: Reactome:R-HSA-191366 "Squalene 2,3-epoxide cyclizes, forming lanosterol" +xref: RHEA:14621 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0000252 +name: C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H." [EC:1.1.1.170, PMID:9811880] +comment: Note that zymosterol is cholesta-8,24-dien-3-ol. +synonym: "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170] +synonym: "3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)" EXACT [] +synonym: "3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [] +synonym: "3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity" RELATED [] +synonym: "C-3 sterol dehydrogenase (C-4 decarboxylase) activity" RELATED [] +synonym: "C-3 sterol dehydrogenase activity" RELATED [] +synonym: "sterol 4alpha-carboxylic decarboxylase activity" RELATED [] +synonym: "sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [] +synonym: "sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)" RELATED [] +xref: EC:1.1.1.170 +xref: Reactome:R-HSA-194642 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one" +xref: Reactome:R-HSA-194718 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0000253 +name: 3-keto sterol reductase activity +namespace: molecular_function +alt_id: GO:0050576 +def: "Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+)." [EC:1.1.1.270, GOC:mah, MetaCyc:1.1.1.270-RXN, MetaCyc:RXN3O-4110, MetaCyc:RXN66-19, MetaCyc:RXN66-24, MetaCyc:RXN66-314, MetaCyc:RXN66-319, PMID:9811880] +comment: Note that zymosterol is cholesta-8,24-dien-3-ol. +synonym: "3-keto-steroid reductase activity" EXACT [] +synonym: "3-KSR activity" EXACT [EC:1.1.1.270] +synonym: "3beta-hydroxy-steroid:NADP+ 3-oxidoreductase" RELATED [EC:1.1.1.270] +xref: EC:1.1.1.270 +xref: MetaCyc:1.1.1.270-RXN +xref: MetaCyc:RXN3O-4110 +xref: MetaCyc:RXN66-19 +xref: MetaCyc:RXN66-24 +xref: MetaCyc:RXN66-314 +xref: MetaCyc:RXN66-319 +xref: Reactome:R-HSA-194632 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol)" +xref: Reactome:R-HSA-194689 "4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol" +xref: RHEA:18409 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0000254 +name: C-4 methylsterol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O." [EC:1.14.18.9, PMID:9811880] +comment: Note that zymosterol is cholesta-8,24-dien-3-ol. +synonym: "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.18.9] +synonym: "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.18.9] +synonym: "4-methylsterol oxidase activity" EXACT [] +synonym: "methylsterol hydroxylase activity" RELATED [] +synonym: "methylsterol monooxygenase activity" RELATED [] +xref: EC:1.14.18.9 +xref: MetaCyc:1.14.13.72-RXN +xref: Reactome:R-HSA-194641 "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol" +xref: Reactome:R-HSA-194669 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol" +xref: RHEA:55220 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0000255 +name: allantoin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism." [GOC:mah, ISBN:0198547684] +synonym: "allantoin metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0000256 +name: allantoin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea." [GOC:mah, ISBN:0198547684] +synonym: "allantoin breakdown" EXACT [] +synonym: "allantoin catabolism" EXACT [] +synonym: "allantoin degradation" EXACT [] +is_a: GO:0000255 ! allantoin metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043605 ! cellular amide catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0000257 +name: nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides." [EC:3.5.5.1, GOC:kd] +synonym: "acetonitrilase activity" EXACT [EC:3.5.5.1] +synonym: "benzonitrilase activity" EXACT [EC:3.5.5.1] +synonym: "nitrile aminohydrolase activity" EXACT [EC:3.5.5.1] +xref: EC:3.5.5.1 +xref: KEGG_REACTION:R00540 +xref: MetaCyc:3.5.5.1-RXN +xref: RHEA:21724 +xref: UM-BBD_enzymeID:e0283 +is_a: GO:0016815 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles + +[Term] +id: GO:0000258 +name: obsolete isoleucine/valine:sodium symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in)." [TC:2.A.26.1.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "isoleucine/valine:sodium symporter activity" EXACT [] +is_obsolete: true +consider: GO:0005283 +consider: GO:0005304 +consider: GO:0015188 + +[Term] +id: GO:0000259 +name: obsolete intracellular nucleoside transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell." [GOC:ai] +comment: This term was made obsolete because it contains component and function information. +synonym: "intracellular nucleoside transmembrane transporter activity" EXACT [] +is_obsolete: true +consider: GO:0005337 +consider: GO:0005622 + +[Term] +id: GO:0000260 +name: obsolete hydrogen-translocating V-type ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria." [TC:3.A.2.2.1, TC:3.A.2.2.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "hydrogen-translocating V-type ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0046961 + +[Term] +id: GO:0000261 +name: obsolete sodium-translocating V-type ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria." [TC:3.A.2.2.2] +comment: This term was made obsolete because it represents a gene product. +synonym: "sodium-translocating V-type ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0046962 + +[Term] +id: GO:0000262 +name: mitochondrial chromosome +namespace: cellular_component +def: "A chromosome found in the mitochondrion of a eukaryotic cell." [GOC:mah] +synonym: "mitochondrial DNA" NARROW [] +synonym: "mitochondrial genome" RELATED [] +synonym: "mtDNA" NARROW [] +xref: NIF_Subcellular:sao1186327184 +is_a: GO:0000229 ! cytoplasmic chromosome +intersection_of: GO:0005694 ! chromosome +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0042645 ! mitochondrial nucleoid + +[Term] +id: GO:0000263 +name: obsolete heterotrimeric G-protein GTPase, alpha-subunit +namespace: molecular_function +def: "OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity." [GOC:mah, ISBN:0198547684] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "heterotrimeric G-protein GTPase, alpha-subunit" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0005834 + +[Term] +id: GO:0000264 +name: obsolete heterotrimeric G-protein GTPase, beta-subunit +namespace: molecular_function +def: "OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit." [GOC:mah, ISBN:0198547684] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "heterotrimeric G-protein GTPase, beta-subunit" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0005834 + +[Term] +id: GO:0000265 +name: obsolete heterotrimeric G-protein GTPase, gamma-subunit +namespace: molecular_function +def: "OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit." [GOC:mah, ISBN:0198547684] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "heterotrimeric G-protein GTPase, gamma-subunit" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0005834 + +[Term] +id: GO:0000266 +name: mitochondrial fission +namespace: biological_process +def: "The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." [PMID:11038192] +synonym: "mitochondrial division" EXACT [] +synonym: "mitochondrial proliferation" RELATED [] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0048285 ! organelle fission + +[Term] +id: GO:0000267 +name: obsolete cell fraction +namespace: cellular_component +def: "OBSOLETE. A generic term for parts of cells prepared by disruptive biochemical techniques." [GOC:ma] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "cell fraction" EXACT [] +is_obsolete: true +consider: GO:0005575 + +[Term] +id: GO:0000268 +name: peroxisome targeting sequence binding +namespace: molecular_function +alt_id: GO:0005051 +def: "Interacting selectively and non-covalently with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome." [GOC:mah, ISBN:0879693568] +synonym: "peroxisome targeting signal receptor" NARROW [] +synonym: "PTS binding" EXACT [] +synonym: "PTS receptor" NARROW [] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0000269 +name: toxin export channel activity +namespace: molecular_function +def: "Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] +is_a: GO:0015288 ! porin activity +is_a: GO:0019534 ! toxin transmembrane transporter activity + +[Term] +id: GO:0000270 +name: peptidoglycan metabolic process +namespace: biological_process +alt_id: GO:0009284 +def: "The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network." [http://www.dsmz.de/species/murein.htm, ISBN:0198506732] +synonym: "murein metabolic process" EXACT [] +synonym: "murein metabolism" EXACT [] +synonym: "peptidoglycan metabolism" EXACT [] +is_a: GO:0030203 ! glycosaminoglycan metabolic process + +[Term] +id: GO:0000271 +name: polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] +synonym: "glycan biosynthesis" EXACT [] +synonym: "glycan biosynthetic process" EXACT [] +synonym: "polysaccharide anabolism" EXACT [] +synonym: "polysaccharide biosynthesis" EXACT [] +synonym: "polysaccharide formation" EXACT [] +synonym: "polysaccharide synthesis" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0016051 ! carbohydrate biosynthetic process + +[Term] +id: GO:0000272 +name: polysaccharide catabolic process +namespace: biological_process +alt_id: GO:0044244 +def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] +synonym: "multicellular organismal polysaccharide catabolic process" NARROW [] +synonym: "polysaccharide breakdown" EXACT [] +synonym: "polysaccharide catabolism" EXACT [] +synonym: "polysaccharide degradation" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0016052 ! carbohydrate catabolic process + +[Term] +id: GO:0000274 +name: mitochondrial proton-transporting ATP synthase, stator stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core." [GOC:mtg_sensu, PMID:10838056] +synonym: "mitochondrial proton-transporting ATP synthase, peripheral stalk" EXACT [] +is_a: GO:0045265 ! proton-transporting ATP synthase, stator stalk +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045265 ! proton-transporting ATP synthase, stator stalk +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0000276 ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) + +[Term] +id: GO:0000275 +name: mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) +namespace: cellular_component +def: "The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled." [GOC:mtg_sensu, PMID:10838056] +comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. +synonym: "hydrogen-transporting ATP synthase, F1 sector" BROAD [] +synonym: "proton-transporting ATP synthase complex, catalytic core F(1)" BROAD [] +is_a: GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005753 ! mitochondrial proton-transporting ATP synthase complex + +[Term] +id: GO:0000276 +name: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) +namespace: cellular_component +def: "All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins." [GOC:mtg_sensu, PMID:10838056] +is_a: GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005753 ! mitochondrial proton-transporting ATP synthase complex + +[Term] +id: GO:0000277 +name: [cytochrome c]-lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c." [EC:2.1.1.59] +synonym: "cytochrome c (lysine) methyltransferase activity" EXACT [EC:2.1.1.59] +synonym: "cytochrome c methyltransferase activity" EXACT [EC:2.1.1.59] +synonym: "cytochrome c-lysine N-methyltransferase activity" EXACT [EC:2.1.1.59] +synonym: "cytochrome c-specific protein methylase III activity" EXACT [EC:2.1.1.59] +synonym: "cytochrome c-specific protein-lysine methyltransferase activity" EXACT [EC:2.1.1.59] +synonym: "S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.59] +synonym: "S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.59] +xref: EC:2.1.1.59 +xref: MetaCyc:2.1.1.59-RXN +is_a: GO:0016279 ! protein-lysine N-methyltransferase activity + +[Term] +id: GO:0000278 +name: mitotic cell cycle +namespace: biological_process +alt_id: GO:0007067 +def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "mitosis" RELATED [] +xref: Wikipedia:Mitosis +is_a: GO:0007049 ! cell cycle +intersection_of: GO:0007049 ! cell cycle +intersection_of: has_part GO:0140014 ! mitotic nuclear division +relationship: has_part GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0000279 +name: M phase +namespace: biological_process +def: "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "M-phase" EXACT [] +xref: Wikipedia:M_phase +is_a: GO:0022403 ! cell cycle phase + +[Term] +id: GO:0000280 +name: nuclear division +namespace: biological_process +def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah] +subset: goslim_pir +synonym: "karyokinesis" RELATED [] +is_a: GO:0048285 ! organelle fission + +[Term] +id: GO:0000281 +name: mitotic cytokinesis +namespace: biological_process +def: "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:mtg_cell_cycle] +subset: goslim_pombe +synonym: "cytokinesis after mitosis" EXACT [] +is_a: GO:0061640 ! cytoskeleton-dependent cytokinesis +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0061640 ! cytoskeleton-dependent cytokinesis +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0000282 +name: cellular bud site selection +namespace: biological_process +def: "The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae." [GOC:mah] +comment: Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (a sibling term, 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283', was created but has since been merged with 'establishment of cell polarity' ; GO:0030010). +synonym: "bud site selection/establishment of cell polarity" BROAD [] +is_a: GO:0030010 ! establishment of cell polarity +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0000281 ! mitotic cytokinesis + +[Term] +id: GO:0000284 +name: obsolete shmoo orientation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable. +synonym: "shmoo orientation" EXACT [] +is_obsolete: true +replaced_by: GO:0000753 + +[Term] +id: GO:0000285 +name: 1-phosphatidylinositol-3-phosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.150, RHEA:13609] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.150] +synonym: "phosphatidylinositol 3-phosphate 5-kinase activity" EXACT [EC:2.7.1.150] +synonym: "phosphatidylinositol-3-phosphate 5-kinase activity" EXACT [] +synonym: "type III PIP kinase activity" RELATED [EC:2.7.1.150] +xref: EC:2.7.1.150 +xref: KEGG_REACTION:R05802 +xref: MetaCyc:2.7.1.150-RXN +xref: Reactome:R-HSA-1675910 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane" +xref: Reactome:R-HSA-1675921 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane" +xref: Reactome:R-HSA-1676134 "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane" +xref: Reactome:R-HSA-1676168 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane" +xref: RHEA:13609 +is_a: GO:0016307 ! phosphatidylinositol phosphate kinase activity + +[Term] +id: GO:0000286 +name: alanine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+)." [EC:1.4.1.1] +synonym: "AlaDH" RELATED [EC:1.4.1.1] +synonym: "alanine oxidoreductase activity" EXACT [EC:1.4.1.1] +synonym: "alpha-alanine dehydrogenase activity" EXACT [EC:1.4.1.1] +synonym: "L-alanine dehydrogenase activity" EXACT [EC:1.4.1.1] +synonym: "L-alanine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.1] +synonym: "NAD-dependent alanine dehydrogenase activity" EXACT [EC:1.4.1.1] +synonym: "NAD-linked alanine dehydrogenase activity" EXACT [EC:1.4.1.1] +synonym: "NADH-dependent alanine dehydrogenase activity" EXACT [EC:1.4.1.1] +xref: EC:1.4.1.1 +xref: MetaCyc:ALANINE-DEHYDROGENASE-RXN +xref: RHEA:18405 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0000287 +name: magnesium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with magnesium (Mg) ions." [GOC:ai] +synonym: "magnesium binding" EXACT [] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0000288 +name: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +namespace: biological_process +def: "A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability." [GOC:jp, GOC:krc] +synonym: "deadenylation-dependent mRNA decay" EXACT [] +synonym: "mRNA breakdown, deadenylation-dependent decay" EXACT [] +synonym: "mRNA catabolic process, deadenylation-dependent" EXACT [] +synonym: "mRNA catabolic process, deadenylylation-dependent" EXACT [] +synonym: "mRNA catabolism, deadenylation-dependent" EXACT [] +synonym: "mRNA catabolism, deadenylylation-dependent" EXACT [] +synonym: "mRNA degradation, deadenylation-dependent decay" EXACT [] +synonym: "nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0000289 +name: nuclear-transcribed mRNA poly(A) tail shortening +namespace: biological_process +def: "Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length." [GOC:krc] +synonym: "3' to 5' mRNA deadenylation" RELATED [] +synonym: "mRNA deadenylation" RELATED [] +synonym: "nuclear mRNA poly(A) tail shortening" RELATED [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process +relationship: part_of GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + +[Term] +id: GO:0000290 +name: deadenylation-dependent decapping of nuclear-transcribed mRNA +namespace: biological_process +def: "Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length." [GOC:krc] +synonym: "deadenylation-dependent decapping of nuclear mRNA" EXACT [] +synonym: "deadenylylation-dependent decapping" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process +is_a: GO:0110156 ! methylguanosine-cap decapping +relationship: part_of GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + +[Term] +id: GO:0000291 +name: nuclear-transcribed mRNA catabolic process, exonucleolytic +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail." [GOC:krc] +synonym: "exonucleolytic degradation of mRNA" EXACT [] +synonym: "mRNA breakdown, exonucleolytic" EXACT [] +synonym: "mRNA degradation, exonucleolytic" EXACT [] +synonym: "nuclear mRNA catabolic process, exonucleolytic" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0000292 +name: RNA fragment catabolic process +namespace: biological_process +alt_id: GO:0030452 +def: "The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing." [GOC:mah] +synonym: "group I intron catabolic process" NARROW [] +synonym: "RNA fragment breakdown" EXACT [] +synonym: "RNA fragment catabolism" EXACT [GOC:mah] +synonym: "RNA fragment degradation" EXACT [] +is_a: GO:0006401 ! RNA catabolic process + +[Term] +id: GO:0000293 +name: ferric-chelate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+)." [EC:1.16.1.7] +comment: Note that this function was formerly EC:1.6.99.13. +synonym: "Fe(II):NAD+ oxidoreductase activity" EXACT [EC:1.16.1.7] +synonym: "ferric chelate reductase activity" EXACT [EC:1.16.1.7] +synonym: "iron chelate reductase activity" RELATED [EC:1.16.1.7] +synonym: "NADH2:Fe3+ oxidoreductase activity" EXACT [EC:1.16.1.7] +synonym: "NADH:Fe(3+) oxidoreductase activity" EXACT [EC:1.16.1.7] +synonym: "NADH:Fe(3+)-EDTA reductase activity" EXACT [EC:1.16.1.7] +synonym: "NADH:Fe3+ oxidoreductase activity" EXACT [EC:1.16.1.7] +synonym: "NADH:Fe3+-EDTA reductase activity" EXACT [EC:1.16.1.7] +xref: EC:1.16.1.7 +xref: MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN +xref: RHEA:15061 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0000294 +name: nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay +namespace: biological_process +def: "A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends." [GOC:krc] +synonym: "endonucleolytic mRNA decay" EXACT [] +synonym: "mRNA breakdown, endonucleolytic cleavage-dependent decay" EXACT [] +synonym: "mRNA catabolic process, endonucleolytic" EXACT [] +synonym: "mRNA catabolism, endonucleolytic" EXACT [] +synonym: "mRNA degradation, endonucleolytic cleavage-dependent decay" EXACT [] +synonym: "nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0000295 +name: adenine nucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other." [PMID:11566870] +xref: Reactome:R-HSA-389652 "PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP" +is_a: GO:0015216 ! purine nucleotide transmembrane transporter activity +relationship: part_of GO:0051503 ! adenine nucleotide transport + +[Term] +id: GO:0000296 +name: spermine transport +namespace: biological_process +def: "The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc, ISBN:0198506732] +is_a: GO:0006812 ! cation transport +is_a: GO:0015846 ! polyamine transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0000297 +name: spermine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication." [GOC:ai] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015203 ! polyamine transmembrane transporter activity +relationship: part_of GO:1903710 ! spermine transmembrane transport + +[Term] +id: GO:0000298 +name: endopolyphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues." [EC:3.6.1.10] +synonym: "metaphosphatase activity" BROAD [EC:3.6.1.10] +synonym: "polymetaphosphatase activity" EXACT [EC:3.6.1.10] +synonym: "polyphosphatase activity" BROAD [EC:3.6.1.10] +synonym: "polyphosphate depolymerase activity" BROAD [EC:3.6.1.10] +synonym: "polyphosphate polyphosphohydrolase activity" EXACT [EC:3.6.1.10] +xref: EC:3.6.1.10 +xref: MetaCyc:ENDOPOLYPHOSPHATASE-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0000299 +name: obsolete integral to membrane of membrane fraction +namespace: cellular_component +def: "OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes." [PMID:10512869] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "integral to membrane of membrane fraction" EXACT [] +is_obsolete: true +consider: GO:0016021 + +[Term] +id: GO:0000300 +name: obsolete peripheral to membrane of membrane fraction +namespace: cellular_component +def: "OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH." [PMID:10512869] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "peripheral to membrane of membrane fraction" EXACT [] +is_obsolete: true +consider: GO:0019898 + +[Term] +id: GO:0000301 +name: retrograde transport, vesicle recycling within Golgi +namespace: biological_process +def: "The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi." [ISBN:0716731363] +synonym: "retrograde (vesicle recycling within Golgi) transport" EXACT [] +is_a: GO:0006891 ! intra-Golgi vesicle-mediated transport + +[Term] +id: GO:0000302 +name: response to reactive oxygen species +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:krc] +synonym: "response to active oxygen species" EXACT [] +synonym: "response to AOS" EXACT [] +synonym: "response to reactive oxidative species" EXACT [] +synonym: "response to reactive oxygen intermediate" EXACT [] +synonym: "response to ROI" EXACT [] +synonym: "response to ROS" EXACT [] +is_a: GO:0006979 ! response to oxidative stress +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0000303 +name: response to superoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:krc, ISBN:0198506732] +is_a: GO:0000305 ! response to oxygen radical + +[Term] +id: GO:0000304 +name: response to singlet oxygen +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst." [GOC:krc, ISBN:0124325653, ISBN:0198506732] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0007584 ! response to nutrient +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0000305 +name: response to oxygen radical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." [GOC:krc, ISBN:0124325653] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0010035 ! response to inorganic substance + +[Term] +id: GO:0000306 +name: extrinsic component of vacuolar membrane +namespace: cellular_component +def: "The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:jl, GOC:mah] +synonym: "extrinsic to vacuolar membrane" EXACT [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005774 ! vacuolar membrane +relationship: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0000307 +name: cyclin-dependent protein kinase holoenzyme complex +namespace: cellular_component +def: "Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner." [GOC:krc, PMID:11602261] +subset: goslim_pir +synonym: "CDK holoenzyme" EXACT [] +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000308 +name: cytoplasmic cyclin-dependent protein kinase holoenzyme complex +namespace: cellular_component +def: "Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm." [GOC:krc] +synonym: "CDK holoenzyme" BROAD [] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +intersection_of: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000309 +name: nicotinamide-nucleotide adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+." [EC:2.7.7.1] +synonym: "adenosine triphosphate-nicotinamide mononucleotide transadenylase activity" EXACT [EC:2.7.7.1] +synonym: "ATP:nicotinamide-nucleotide adenylyltransferase activity" EXACT [] +synonym: "ATP:NMN adenylyltransferase activity" EXACT [EC:2.7.7.1] +synonym: "diphosphopyridine nucleotide pyrophosphorylase activity" RELATED [EC:2.7.7.1] +synonym: "NAD(+) diphosphorylase activity" NARROW [EC:2.7.7.1] +synonym: "NAD(+) pyrophosphorylase activity" NARROW [EC:2.7.7.1] +synonym: "NAD+ diphosphorylase activity" EXACT [EC:2.7.7.1] +synonym: "NAD+ pyrophosphorylase activity" EXACT [EC:2.7.7.1] +synonym: "nicotinamide adenine dinucleotide pyrophosphorylase activity" NARROW [EC:2.7.7.1] +synonym: "nicotinamide mononucleotide adenylyltransferase activity" NARROW [EC:2.7.7.1] +synonym: "NMN adenylyltransferase activity" NARROW [EC:2.7.7.1] +synonym: "NMNAT activity" NARROW [EC:2.7.7.1] +xref: EC:2.7.7.1 +xref: MetaCyc:2.7.7.1-RXN +xref: Reactome:R-HSA-8939959 "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+" +xref: RHEA:21360 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0000310 +name: xanthine phosphoribosyltransferase activity +namespace: molecular_function +alt_id: GO:0009043 +def: "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate." [EC:2.4.2.22, GOC:clt] +synonym: "5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.22] +synonym: "Xan phosphoribosyltransferase activity" EXACT [EC:2.4.2.22] +synonym: "xanthine-guanine phosphoribosyltransferase activity" EXACT [] +synonym: "xanthosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.22] +synonym: "xanthylate pyrophosphorylase activity" EXACT [EC:2.4.2.22] +synonym: "xanthylic pyrophosphorylase activity" EXACT [EC:2.4.2.22] +synonym: "XMP pyrophosphorylase activity" EXACT [EC:2.4.2.22] +synonym: "XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.22] +xref: EC:2.4.2.22 +xref: MetaCyc:XANPRIBOSYLTRAN-RXN +xref: RHEA:10800 +is_a: GO:0106130 ! purine phosphoribosyltransferase activity + +[Term] +id: GO:0000311 +name: plastid large ribosomal subunit +namespace: cellular_component +def: "The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] +is_a: GO:0000315 ! organellar large ribosomal subunit +intersection_of: GO:0015934 ! large ribosomal subunit +intersection_of: part_of GO:0009547 ! plastid ribosome +relationship: part_of GO:0009547 ! plastid ribosome + +[Term] +id: GO:0000312 +name: plastid small ribosomal subunit +namespace: cellular_component +def: "The smaller of the two subunits of a plastid ribosome." [GOC:mcc] +is_a: GO:0000314 ! organellar small ribosomal subunit +intersection_of: GO:0015935 ! small ribosomal subunit +intersection_of: part_of GO:0009547 ! plastid ribosome +relationship: part_of GO:0009547 ! plastid ribosome + +[Term] +id: GO:0000313 +name: organellar ribosome +namespace: cellular_component +def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc] +is_a: GO:0005840 ! ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0043226 ! organelle +relationship: part_of GO:0043226 ! organelle + +[Term] +id: GO:0000314 +name: organellar small ribosomal subunit +namespace: cellular_component +def: "The smaller of the two subunits of an organellar ribosome." [GOC:mcc] +is_a: GO:0015935 ! small ribosomal subunit +intersection_of: GO:0015935 ! small ribosomal subunit +intersection_of: part_of GO:0000313 ! organellar ribosome +relationship: part_of GO:0000313 ! organellar ribosome + +[Term] +id: GO:0000315 +name: organellar large ribosomal subunit +namespace: cellular_component +def: "The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] +is_a: GO:0015934 ! large ribosomal subunit +intersection_of: GO:0015934 ! large ribosomal subunit +intersection_of: part_of GO:0000313 ! organellar ribosome +relationship: part_of GO:0000313 ! organellar ribosome + +[Term] +id: GO:0000316 +name: sulfite transport +namespace: biological_process +def: "The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "sulphite transport" EXACT [] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0000319 +name: sulfite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sulfite ions from one side of a membrane to the other." [GOC:as] +synonym: "sulphite transporter activity" EXACT [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0000316 ! sulfite transport + +[Term] +id: GO:0000320 +name: re-entry into mitotic cell cycle +namespace: biological_process +def: "The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state." [GOC:krc] +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0000321 +name: re-entry into mitotic cell cycle after pheromone arrest +namespace: biological_process +def: "The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae." [GOC:krc, PMID:9927449] +is_a: GO:0000320 ! re-entry into mitotic cell cycle +is_a: GO:0000754 ! adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion + +[Term] +id: GO:0000322 +name: storage vacuole +namespace: cellular_component +def: "A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules." [GOC:krc] +is_a: GO:0005773 ! vacuole + +[Term] +id: GO:0000323 +name: lytic vacuole +namespace: cellular_component +def: "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." [GOC:krc] +is_a: GO:0005773 ! vacuole + +[Term] +id: GO:0000324 +name: fungal-type vacuole +namespace: cellular_component +def: "A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure." [GOC:mah, GOC:mtg_sensu, ISBN:0879693649] +synonym: "vacuole, cell cycle-correlated morphology" EXACT [] +is_a: GO:0000322 ! storage vacuole +is_a: GO:0000323 ! lytic vacuole + +[Term] +id: GO:0000325 +name: plant-type vacuole +namespace: cellular_component +def: "A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0815316208] +synonym: "vacuole, cell cycle-independent morphology" EXACT [] +is_a: GO:0005773 ! vacuole + +[Term] +id: GO:0000326 +name: protein storage vacuole +namespace: cellular_component +def: "A storage vacuole that contains a lytic vacuole; identified in plants." [PMID:11739409] +is_a: GO:0000322 ! storage vacuole +is_a: GO:0000325 ! plant-type vacuole + +[Term] +id: GO:0000327 +name: lytic vacuole within protein storage vacuole +namespace: cellular_component +def: "A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole." [PMID:11739490] +is_a: GO:0000323 ! lytic vacuole +intersection_of: GO:0000323 ! lytic vacuole +intersection_of: part_of GO:0000326 ! protein storage vacuole +relationship: part_of GO:0000326 ! protein storage vacuole + +[Term] +id: GO:0000328 +name: fungal-type vacuole lumen +namespace: cellular_component +def: "The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae." [GOC:krc, GOC:mtg_sensu] +synonym: "lumen of vacuole with cell cycle-correlated morphology" EXACT [] +is_a: GO:0005775 ! vacuolar lumen +relationship: part_of GO:0000324 ! fungal-type vacuole + +[Term] +id: GO:0000329 +name: fungal-type vacuole membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae." [GOC:krc, GOC:mtg_sensu] +synonym: "fungal-type vacuolar membrane" RELATED [] +synonym: "membrane of vacuole with cell cycle-correlated morphology" EXACT [] +is_a: GO:0098852 ! lytic vacuole membrane +relationship: part_of GO:0000324 ! fungal-type vacuole + +[Term] +id: GO:0000330 +name: plant-type vacuole lumen +namespace: cellular_component +def: "The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana." [GOC:krc, GOC:mtg_sensu] +synonym: "lumen of vacuole with cell cycle-independent morphology" EXACT [] +is_a: GO:0005775 ! vacuolar lumen +relationship: part_of GO:0000325 ! plant-type vacuole + +[Term] +id: GO:0000331 +name: contractile vacuole +namespace: cellular_component +def: "A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory." [GOC:jl, PMID:10503189, PMID:23890380] +synonym: "central bladder" RELATED [PMID:23890380] +synonym: "central vacuole" RELATED [PMID:23890380] +xref: Wikipedia:Contractile_vacuole +is_a: GO:0005773 ! vacuole +is_a: GO:0031410 ! cytoplasmic vesicle +relationship: part_of GO:0062159 ! contractile vacuole complex + +[Term] +id: GO:0000332 +name: template for synthesis of G-rich strand of telomere DNA activity +namespace: molecular_function +def: "Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA." [PMID:11812242] +comment: Note that this term describes the activity of an RNA gene product that interacts with other nucleic acid molecules via base pairing; it should not be used to annotate proteins. +synonym: "telomerase RNA" EXACT [] +synonym: "telomerase, template" EXACT [] +is_a: GO:0000497 ! DNA template activity +relationship: part_of GO:0003720 ! telomerase activity + +[Term] +id: GO:0000333 +name: telomerase catalytic core complex +namespace: cellular_component +def: "The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition." [GOC:BHF-UCL, PMID:11884619, PMID:1808260] +synonym: "TERT-TERC complex" RELATED [GOC:nc, PMID:19701182] +is_a: GO:0005697 ! telomerase holoenzyme complex +is_a: GO:0042575 ! DNA polymerase complex + +[Term] +id: GO:0000334 +name: 3-hydroxyanthranilate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)." [EC:1.13.11.6, RHEA:17953] +synonym: "3-hydroxyanthranilate oxygenase activity" EXACT [EC:1.13.11.6] +synonym: "3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.6] +synonym: "3-hydroxyanthranilic acid dioxygenase activity" EXACT [EC:1.13.11.6] +synonym: "3-hydroxyanthranilic acid oxygenase activity" EXACT [EC:1.13.11.6] +synonym: "3-hydroxyanthranilic oxygenase activity" EXACT [EC:1.13.11.6] +synonym: "3HAO" RELATED [EC:1.13.11.6] +xref: EC:1.13.11.6 +xref: KEGG_REACTION:R02665 +xref: MetaCyc:1.13.11.6-RXN +xref: Reactome:R-HSA-71218 "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde" +xref: RHEA:17953 +xref: UM-BBD_reactionID:r1027 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0000335 +name: negative regulation of transposition, DNA-mediated +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc, GOC:tb] +synonym: "down regulation of DNA transposition" EXACT [] +synonym: "down-regulation of DNA transposition" EXACT [] +synonym: "downregulation of DNA transposition" EXACT [] +synonym: "inhibition of DNA transposition" NARROW [] +synonym: "negative regulation of DNA transposition" EXACT [GOC:dph] +is_a: GO:0000337 ! regulation of transposition, DNA-mediated +is_a: GO:0010529 ! negative regulation of transposition +is_a: GO:0045910 ! negative regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006313 ! transposition, DNA-mediated +relationship: negatively_regulates GO:0006313 ! transposition, DNA-mediated + +[Term] +id: GO:0000336 +name: positive regulation of transposition, DNA-mediated +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc] +synonym: "activation of DNA transposition" NARROW [] +synonym: "positive regulation of DNA transposition" EXACT [GOC:dph] +synonym: "stimulation of DNA transposition" NARROW [] +synonym: "up regulation of DNA transposition" EXACT [] +synonym: "up-regulation of DNA transposition" EXACT [] +synonym: "upregulation of DNA transposition" EXACT [] +is_a: GO:0000337 ! regulation of transposition, DNA-mediated +is_a: GO:0010530 ! positive regulation of transposition +is_a: GO:0045911 ! positive regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006313 ! transposition, DNA-mediated +relationship: positively_regulates GO:0006313 ! transposition, DNA-mediated + +[Term] +id: GO:0000337 +name: regulation of transposition, DNA-mediated +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule." [GOC:dph, GOC:krc] +synonym: "regulation of DNA transposition" EXACT [GOC:dph] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:0010528 ! regulation of transposition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006313 ! transposition, DNA-mediated +relationship: regulates GO:0006313 ! transposition, DNA-mediated + +[Term] +id: GO:0000338 +name: protein deneddylation +namespace: biological_process +alt_id: GO:0010388 +def: "The removal of a ubiquitin-like protein of the NEDD8 type from a protein." [GOC:krc] +synonym: "cullin deneddylation" NARROW [] +is_a: GO:0070646 ! protein modification by small protein removal + +[Term] +id: GO:0000339 +name: RNA cap binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule." [GOC:krc] +synonym: "binding to mRNA cap" NARROW [] +synonym: "mRNA cap binding" NARROW [] +synonym: "snRNA cap binding" NARROW [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0000340 +name: RNA 7-methylguanosine cap binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II." [GOC:krc] +synonym: "RNA m7G cap binding" EXACT [] +is_a: GO:0000339 ! RNA cap binding + +[Term] +id: GO:0000341 +name: RNA trimethylguanosine cap binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans." [GOC:krc] +synonym: "RNA m2,2,7G cap binding" EXACT [] +is_a: GO:0000339 ! RNA cap binding + +[Term] +id: GO:0000342 +name: RNA cap 4 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa." [GOC:krc, PMID:10880518, PMID:12121975] +is_a: GO:0000339 ! RNA cap binding + +[Term] +id: GO:0000343 +name: plastid-encoded plastid RNA polymerase complex A +namespace: cellular_component +def: "A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex." [PMID:10946105] +synonym: "PEP-A" EXACT [] +is_a: GO:0000427 ! plastid-encoded plastid RNA polymerase complex + +[Term] +id: GO:0000344 +name: plastid-encoded plastid RNA polymerase complex B +namespace: cellular_component +def: "A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation." [PMID:10946105] +synonym: "PEP-B" EXACT [] +is_a: GO:0000427 ! plastid-encoded plastid RNA polymerase complex + +[Term] +id: GO:0000345 +name: cytosolic DNA-directed RNA polymerase complex +namespace: cellular_component +def: "The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity." [PMID:11158566] +is_a: GO:0000428 ! DNA-directed RNA polymerase complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0000346 +name: transcription export complex +namespace: cellular_component +def: "The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans." [GOC:krc, PMID:11979277] +subset: goslim_pir +synonym: "TREX complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000347 +name: THO complex +namespace: cellular_component +def: "The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits." [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000348 +name: mRNA branch site recognition +namespace: biological_process +alt_id: GO:0000370 +alt_id: GO:0000371 +def: "Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome." [GOC:krc, ISBN:0879695897] +comment: Note that this step represents the formation of the B complex (yeast) or the A complex (mammalian). +synonym: "nuclear mRNA branch site recognition" EXACT [GOC:vw] +synonym: "spliceosomal A complex biosynthesis" NARROW [] +synonym: "spliceosomal A complex formation" NARROW [] +synonym: "spliceosomal B complex biosynthesis" NARROW [] +synonym: "spliceosomal B complex formation" NARROW [] +synonym: "U12-type nuclear mRNA branch site recognition" NARROW [] +synonym: "U2-type nuclear mRNA branch site recognition" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000245 ! spliceosomal complex assembly + +[Term] +id: GO:0000349 +name: generation of catalytic spliceosome for first transesterification step +namespace: biological_process +alt_id: GO:0000356 +alt_id: GO:0000357 +def: "Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome." [GOC:krc, ISBN:0879695897] +comment: Note that this step represents the formation of the A2-2 complex (yeast) or the C1 complex (mammalian). +synonym: "catalytic spliceosome assembly for first transesterification step" RELATED [] +synonym: "formation of catalytic spliceosome for first transesterification step" EXACT [] +synonym: "spliceosomal A2-2 complex biosynthesis" NARROW [] +synonym: "spliceosomal A2-2 complex formation" NARROW [] +synonym: "spliceosomal C1 complex biosynthesis" NARROW [] +synonym: "spliceosomal C1 complex formation" NARROW [] +synonym: "U12-type catalytic spliceosome formation for first transesterification step" NARROW [] +synonym: "U2-type catalytic spliceosome formation for first transesterification step" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000393 ! spliceosomal conformational changes to generate catalytic conformation + +[Term] +id: GO:0000350 +name: generation of catalytic spliceosome for second transesterification step +namespace: biological_process +alt_id: GO:0000358 +alt_id: GO:0000359 +def: "Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing." [GOC:krc, ISBN:0879695897] +comment: Note that this step represents formation of the A2-3 complex (yeast) or the C2 complex (mammalian). +synonym: "catalytic spliceosome assembly for second transesterification step" RELATED [] +synonym: "formation of catalytic spliceosome for second transesterification step" EXACT [] +synonym: "formation of catalytic U12-type spliceosome for second transesterification step" NARROW [] +synonym: "formation of catalytic U2-type spliceosome for second transesterification step" NARROW [] +synonym: "formation of spliceosomal A2-2 complex" NARROW [] +synonym: "formation of spliceosomal C1 complex" NARROW [] +synonym: "lariat formation, 5'-splice site cleavage" RELATED [] +synonym: "spliceosomal A2-3 complex biosynthesis" NARROW [] +synonym: "spliceosomal A2-3 complex formation" NARROW [] +synonym: "spliceosomal C2 complex biosynthesis" NARROW [] +synonym: "spliceosomal C2 complex formation" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000393 ! spliceosomal conformational changes to generate catalytic conformation + +[Term] +id: GO:0000352 +name: trans assembly of SL-containing precatalytic spliceosome +namespace: biological_process +def: "Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA." [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] +synonym: "trans assembly of spliced leader-containing precatalytic spliceosome" EXACT [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000245 ! spliceosomal complex assembly +relationship: part_of GO:0045291 ! mRNA trans splicing, SL addition + +[Term] +id: GO:0000353 +name: formation of quadruple SL/U4/U5/U6 snRNP +namespace: biological_process +def: "Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA." [GOC:krc, ISBN:0879695897] +comment: Note that this step is analogous to 5' splice site selection in cis-splicing. +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0045291 ! mRNA trans splicing, SL addition + +[Term] +id: GO:0000354 +name: cis assembly of pre-catalytic spliceosome +namespace: biological_process +alt_id: GO:0000360 +alt_id: GO:0000361 +def: "Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner." [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] +comment: Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals). +synonym: "cis assembly of U12-type pre-catalytic spliceosome" NARROW [] +synonym: "cis assembly of U2-type pre-catalytic spliceosome" NARROW [] +synonym: "formation of spliceosomal A2-1 complex" NARROW [] +synonym: "formation of spliceosomal B1 complex" NARROW [] +synonym: "spliceosomal A2-1 complex biosynthesis" NARROW [] +synonym: "spliceosomal A2-1 complex formation" NARROW [] +synonym: "spliceosomal B1 complex biosynthesis" NARROW [] +synonym: "spliceosomal B1 complex formation" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000245 ! spliceosomal complex assembly +relationship: part_of GO:0045292 ! mRNA cis splicing, via spliceosome + +[Term] +id: GO:0000362 +name: obsolete first U2-type spliceosomal transesterification activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins." [GOC:krc, ISBN:0879695897] +comment: This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not. +synonym: "first U2-type spliceosomal transesterification activity" EXACT [] +synonym: "lariat formation, 5'-splice site cleavage" BROAD [] +is_obsolete: true +replaced_by: GO:0000384 + +[Term] +id: GO:0000363 +name: obsolete first U12-type spliceosomal transesterification activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins." [GOC:krc, ISBN:0879695897] +comment: This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not. +synonym: "first U12-type spliceosomal transesterification activity" EXACT [] +synonym: "lariat formation, 5'-splice site cleavage" BROAD [] +is_obsolete: true +replaced_by: GO:0000384 + +[Term] +id: GO:0000364 +name: obsolete second U2-type spliceosomal transesterification activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins." [GOC:krc, ISBN:0879695897] +comment: This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not. +synonym: "3'-splice site cleavage, exon ligation" BROAD [] +synonym: "second U2-type spliceosomal transesterification activity" EXACT [] +is_obsolete: true +replaced_by: GO:0000386 + +[Term] +id: GO:0000365 +name: mRNA trans splicing, via spliceosome +namespace: biological_process +def: "The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0879695897, PMID:18458335] +synonym: "nuclear mRNA trans splicing, via spliceosome" EXACT [GOC:vw] +synonym: "nuclear mRNA trans splicing, via U2-type spliceosome" NARROW [] +is_a: GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000366 +name: intergenic mRNA trans splicing +namespace: biological_process +def: "The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing." [GOC:krc, PMID:11726664, PMID:12110900] +synonym: "intergenic nuclear mRNA trans splicing" EXACT [GOC:vw] +is_a: GO:0000365 ! mRNA trans splicing, via spliceosome +is_a: GO:0000380 ! alternative mRNA splicing, via spliceosome + +[Term] +id: GO:0000367 +name: obsolete second U12-type spliceosomal transesterification activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins." [GOC:krc, ISBN:0879695897] +comment: This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not. +synonym: "3'-splice site cleavage, exon ligation" BROAD [] +synonym: "second U12-type spliceosomal transesterification activity" EXACT [] +is_obsolete: true +replaced_by: GO:0000386 + +[Term] +id: GO:0000372 +name: Group I intron splicing +namespace: biological_process +def: "The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize)." [GOC:krc, PMID:11377794] +comment: Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone). +synonym: "mRNA splicing" RELATED [] +is_a: GO:0000376 ! RNA splicing, via transesterification reactions with guanosine as nucleophile + +[Term] +id: GO:0000373 +name: Group II intron splicing +namespace: biological_process +def: "The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat." [GOC:krc, PMID:11377794] +comment: Note that Group II introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; and mRNA of bacteria. +synonym: "mRNA splicing" RELATED [] +is_a: GO:0000377 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile + +[Term] +id: GO:0000374 +name: Group III intron splicing +namespace: biological_process +def: "The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved." [GOC:krc, PMID:11377794] +comment: Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists. +synonym: "mRNA splicing" RELATED [] +is_a: GO:0000377 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile + +[Term] +id: GO:0000375 +name: RNA splicing, via transesterification reactions +namespace: biological_process +alt_id: GO:0000385 +alt_id: GO:0031202 +def: "Splicing of RNA via a series of two transesterification reactions." [GOC:krc] +comment: Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism. +subset: goslim_pir +synonym: "pre-mRNA splicing factor activity" RELATED [GOC:krc, GOC:mah] +synonym: "RNA splicing factor activity, transesterification mechanism" RELATED [GOC:krc, GOC:mah] +synonym: "spliceosomal catalysis" RELATED [] +is_a: GO:0008380 ! RNA splicing + +[Term] +id: GO:0000376 +name: RNA splicing, via transesterification reactions with guanosine as nucleophile +namespace: biological_process +def: "Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile." [GOC:krc, PMID:11377794] +is_a: GO:0000375 ! RNA splicing, via transesterification reactions + +[Term] +id: GO:0000377 +name: RNA splicing, via transesterification reactions with bulged adenosine as nucleophile +namespace: biological_process +def: "Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure." [GOC:krc, PMID:11377794] +synonym: "lariat RNA biosynthesis" RELATED [] +synonym: "lariat RNA formation" RELATED [] +is_a: GO:0000375 ! RNA splicing, via transesterification reactions + +[Term] +id: GO:0000378 +name: RNA exon ligation +namespace: biological_process +def: "The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction." [GOC:krc, ISBN:0879695897] +comment: Note that this is not a part of spliceosomal RNA splicing. +is_a: GO:0016070 ! RNA metabolic process +relationship: part_of GO:0000394 ! RNA splicing, via endonucleolytic cleavage and ligation + +[Term] +id: GO:0000379 +name: tRNA-type intron splice site recognition and cleavage +namespace: biological_process +def: "RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs." [GOC:krc, GOC:mah, ISBN:0879695897] +is_a: GO:0006396 ! RNA processing +relationship: part_of GO:0006388 ! tRNA splicing, via endonucleolytic cleavage and ligation + +[Term] +id: GO:0000380 +name: alternative mRNA splicing, via spliceosome +namespace: biological_process +def: "The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition." [GOC:krc, PMID:12110900] +comment: Note that this process most commonly occurs in cis, selecting or skipping exons from the same primary transcript, but it has also been observed to occur in trans at low frequency, at least in some mammals. +synonym: "alternative nuclear mRNA splicing, via spliceosome" EXACT [GOC:vw] +synonym: "splice site selection" BROAD [] +is_a: GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000381 +name: regulation of alternative mRNA splicing, via spliceosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs." [GOC:krc] +synonym: "regulation of alternative nuclear mRNA splicing, via spliceosome" EXACT [GOC:vw] +synonym: "splice site selection" BROAD [] +is_a: GO:0048024 ! regulation of mRNA splicing, via spliceosome +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000380 ! alternative mRNA splicing, via spliceosome +relationship: regulates GO:0000380 ! alternative mRNA splicing, via spliceosome + +[Term] +id: GO:0000384 +name: first spliceosomal transesterification activity +namespace: molecular_function +def: "Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon." [GOC:krc, ISBN:0879695897] +synonym: "lariat formation, 5'-splice site cleavage" RELATED [] +is_a: GO:0140098 ! catalytic activity, acting on RNA +relationship: part_of GO:0000375 ! RNA splicing, via transesterification reactions + +[Term] +id: GO:0000386 +name: second spliceosomal transesterification activity +namespace: molecular_function +def: "Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure." [GOC:krc, ISBN:0879695897] +synonym: "3'-splice site cleavage, exon ligation" BROAD [] +synonym: "lariat formation, 5'-splice site cleavage" RELATED [] +is_a: GO:0140098 ! catalytic activity, acting on RNA +relationship: part_of GO:0000375 ! RNA splicing, via transesterification reactions + +[Term] +id: GO:0000387 +name: spliceosomal snRNP assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome." [GOC:krc, GOC:mah, ISBN:0879695897] +synonym: "spliceosomal snRNP biogenesis" RELATED [GOC:mah] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000388 +name: spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) +namespace: biological_process +alt_id: GO:0000396 +alt_id: GO:0000397 +def: "Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11)." [GOC:krc, ISBN:0879695897] +comment: Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian). +synonym: "3'-splice site cleavage, exon ligation" BROAD [] +synonym: "spliceosomal A1 complex biosynthesis" NARROW [] +synonym: "spliceosomal A1 complex formation" NARROW [] +synonym: "spliceosomal B2 complex biosynthesis" NARROW [] +synonym: "spliceosomal B2 complex formation" NARROW [] +synonym: "U12-type spliceosome conformational change to release U4atac and U11" NARROW [] +synonym: "U2-type spliceosome conformational change to release U4 and U1" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000393 ! spliceosomal conformational changes to generate catalytic conformation + +[Term] +id: GO:0000389 +name: mRNA 3'-splice site recognition +namespace: biological_process +alt_id: GO:0000382 +alt_id: GO:0000383 +def: "Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome." [GOC:krc, ISBN:0879695897] +synonym: "nuclear mRNA 3'-splice site recognition" EXACT [GOC:vw] +synonym: "U12-type nuclear mRNA 3'-splice site recognition" NARROW [] +synonym: "U2-type nuclear mRNA 3'-splice site recognition" NARROW [] +is_a: GO:0006376 ! mRNA splice site selection + +[Term] +id: GO:0000390 +name: spliceosomal complex disassembly +namespace: biological_process +alt_id: GO:0000391 +alt_id: GO:0000392 +def: "Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure." [GOC:krc, ISBN:0879695897] +synonym: "spliceosome complex disassembly" EXACT [] +synonym: "spliceosome disassembly" BROAD [] +synonym: "U12-type spliceosome disassembly" NARROW [] +synonym: "U2-type spliceosome disassembly" NARROW [] +is_a: GO:0032988 ! ribonucleoprotein complex disassembly +relationship: part_of GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000393 +name: spliceosomal conformational changes to generate catalytic conformation +namespace: biological_process +def: "Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation." [GOC:krc] +synonym: "3'-splice site cleavage, exon ligation" BROAD [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0000394 +name: RNA splicing, via endonucleolytic cleavage and ligation +namespace: biological_process +def: "Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons." [GOC:krc, ISBN:0879695897] +comment: Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis. +synonym: "mRNA splicing" BROAD [] +is_a: GO:0008380 ! RNA splicing + +[Term] +id: GO:0000395 +name: mRNA 5'-splice site recognition +namespace: biological_process +alt_id: GO:0000368 +alt_id: GO:0000369 +def: "Recognition of the intron 5'-splice site by components of the assembling spliceosome." [GOC:krc, ISBN:0879695897] +comment: Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian). +synonym: "nuclear mRNA 5' splice site recognition" EXACT [] +synonym: "nuclear mRNA 5'-splice site recognition" EXACT [GOC:vw] +synonym: "spliceosomal CC complex biosynthesis" NARROW [] +synonym: "spliceosomal CC complex formation" NARROW [] +synonym: "spliceosomal commitment complex biosynthesis" NARROW [] +synonym: "spliceosomal commitment complex formation" NARROW [] +synonym: "spliceosomal E complex biosynthesis" NARROW [] +synonym: "spliceosomal E complex formation" NARROW [] +synonym: "U12-type nuclear mRNA 5' splice site recognition" NARROW [] +synonym: "U12-type nuclear mRNA 5'-splice site recognition" NARROW [] +synonym: "U2-type nuclear mRNA 5' splice site recognition" NARROW [] +synonym: "U2-type nuclear mRNA 5'-splice site recognition" NARROW [] +is_a: GO:0006376 ! mRNA splice site selection +relationship: part_of GO:0045292 ! mRNA cis splicing, via spliceosome + +[Term] +id: GO:0000398 +name: mRNA splicing, via spliceosome +namespace: biological_process +alt_id: GO:0006374 +alt_id: GO:0006375 +def: "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732, ISBN:0879695897] +comment: Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. +synonym: "mRNA splicing" BROAD [] +synonym: "nuclear mRNA splicing via U12-type spliceosome" NARROW [] +synonym: "nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "nuclear mRNA splicing, via spliceosome" EXACT [GOC:krc, GOC:vw] +synonym: "pre-mRNA splicing" BROAD [] +synonym: "splicing AT-AC intron" RELATED [] +synonym: "splicing GT-AG intron" RELATED [] +is_a: GO:0000377 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile +is_a: GO:0006397 ! mRNA processing + +[Term] +id: GO:0000399 +name: cellular bud neck septin structure +namespace: cellular_component +def: "Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle." [GOC:krc] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005935 ! cellular bud neck +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0000400 +name: four-way junction DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices." [GOC:krc, ISBN:0815332181, PMID:15563464] +synonym: "forked DNA binding" BROAD [] +synonym: "Holliday junction binding" EXACT [] +is_a: GO:0000217 ! DNA secondary structure binding + +[Term] +id: GO:0000401 +name: open form four-way junction DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over." [GOC:krc, ISBN:0815332181, PMID:15563464] +synonym: "open form Holliday junction binding" EXACT [] +is_a: GO:0000400 ! four-way junction DNA binding + +[Term] +id: GO:0000402 +name: crossed form four-way junction DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands." [GOC:krc, ISBN:0815332181, PMID:15563464] +synonym: "crossed form Holliday junction binding" EXACT [] +is_a: GO:0000400 ! four-way junction DNA binding + +[Term] +id: GO:0000403 +name: Y-form DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end." [GOC:elh, PMID:16781730] +synonym: "forked DNA binding" BROAD [] +synonym: "splayed Y-form DNA binding" EXACT [] +is_a: GO:0000217 ! DNA secondary structure binding + +[Term] +id: GO:0000404 +name: heteroduplex DNA loop binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration." [GOC:elh, PMID:16781730] +synonym: "loop DNA binding" RELATED [GOC:jh] +is_a: GO:0000217 ! DNA secondary structure binding +is_a: GO:0032135 ! DNA insertion or deletion binding + +[Term] +id: GO:0000405 +name: bubble DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA." [GOC:elh, GOC:vw, PMID:16781730] +is_a: GO:0000217 ! DNA secondary structure binding + +[Term] +id: GO:0000406 +name: double-strand/single-strand DNA junction binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA." [GOC:elh, PMID:16781730] +is_a: GO:0000217 ! DNA secondary structure binding + +[Term] +id: GO:0000407 +name: phagophore assembly site +namespace: cellular_component +def: "Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction." [GOC:elh, PMID:11689437, PMID:12048214, PMID:12554655] +synonym: "PAS" EXACT [] +synonym: "perivacuolar space" NARROW [] +synonym: "pre-autophagosomal structure" NARROW [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0000408 +name: EKC/KEOPS complex +namespace: cellular_component +def: "A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p." [GOC:elh, GOC:vw, PMID:16564010, PMID:16874308, PMID:21183954, PMID:23945934] +synonym: "endopeptidase-like kinase chromatin-associated protein complex" EXACT [] +synonym: "KEOPS/EKC complex" EXACT [PMID:21183954, PMID:23945934] +synonym: "kinase, putative endopeptidase and other proteins of small size protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000409 +name: regulation of transcription by galactose +namespace: biological_process +def: "Any process involving galactose that modulates the frequency, rate or extent or transcription." [GOC:go_curators] +is_a: GO:0006355 ! regulation of transcription, DNA-templated + +[Term] +id: GO:0000410 +name: carbon catabolite repression of transcription by galactose +namespace: biological_process +def: "A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances." [GOC:mah] +synonym: "down regulation of transcription by galactose" EXACT [] +synonym: "down-regulation of transcription by galactose" EXACT [] +synonym: "downregulation of transcription by galactose" EXACT [] +synonym: "inhibition of transcription by galactose" NARROW [] +is_a: GO:0000409 ! regulation of transcription by galactose +is_a: GO:0045013 ! carbon catabolite repression of transcription + +[Term] +id: GO:0000411 +name: positive regulation of transcription by galactose +namespace: biological_process +def: "Any process involving galactose that activates or increases the rate of transcription." [GOC:go_curators] +synonym: "activation of transcription by galactose" NARROW [] +synonym: "stimulation of transcription by galactose" NARROW [] +synonym: "up regulation of transcription by galactose" EXACT [] +synonym: "up-regulation of transcription by galactose" EXACT [] +synonym: "upregulation of transcription by galactose" EXACT [] +is_a: GO:0000409 ! regulation of transcription by galactose +is_a: GO:0045991 ! carbon catabolite activation of transcription + +[Term] +id: GO:0000412 +name: histone peptidyl-prolyl isomerization +namespace: biological_process +def: "The modification of a histone by cis-trans isomerization of a proline residue." [GOC:krc] +synonym: "histone proline isomerization" EXACT [] +is_a: GO:0000413 ! protein peptidyl-prolyl isomerization +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0000413 +name: protein peptidyl-prolyl isomerization +namespace: biological_process +def: "The modification of a protein by cis-trans isomerization of a proline residue." [GOC:krc, PMID:16959570] +synonym: "protein proline isomerization" EXACT [] +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0000414 +name: regulation of histone H3-K36 methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010452 ! histone H3-K36 methylation +relationship: regulates GO:0010452 ! histone H3-K36 methylation + +[Term] +id: GO:0000415 +name: negative regulation of histone H3-K36 methylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] +synonym: "down regulation of histone H3-K36 methylation" EXACT [] +synonym: "down-regulation of histone H3-K36 methylation" EXACT [] +synonym: "downregulation of histone H3-K36 methylation" EXACT [] +synonym: "inhibition of histone H3-K36 methylation" NARROW [] +is_a: GO:0000414 ! regulation of histone H3-K36 methylation +is_a: GO:0031061 ! negative regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010452 ! histone H3-K36 methylation +relationship: negatively_regulates GO:0010452 ! histone H3-K36 methylation + +[Term] +id: GO:0000416 +name: positive regulation of histone H3-K36 methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] +synonym: "activation of histone H3-K36 methylation" NARROW [] +synonym: "stimulation of histone H3-K36 methylation" NARROW [] +synonym: "up regulation of histone H3-K36 methylation" EXACT [] +synonym: "up-regulation of histone H3-K36 methylation" EXACT [] +synonym: "upregulation of histone H3-K36 methylation" EXACT [] +is_a: GO:0000414 ! regulation of histone H3-K36 methylation +is_a: GO:0031062 ! positive regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010452 ! histone H3-K36 methylation +relationship: positively_regulates GO:0010452 ! histone H3-K36 methylation + +[Term] +id: GO:0000417 +name: HIR complex +namespace: cellular_component +def: "A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p." [GOC:elh, GOC:mah, PMID:16303565, PMID:17180700] +synonym: "HIRA complex" EXACT [PMID:19620282, PMID:20976105] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0000418 +name: RNA polymerase IV complex +namespace: cellular_component +alt_id: GO:0000420 +def: "RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex." [GOC:krc, GOC:mtg_sensu, PMID:15692015, PMID:15766525, PMID:16140984, PMID:19110459] +synonym: "DNA-directed RNA polymerase IV complex" EXACT [] +synonym: "DNA-directed RNA polymerase IVa complex" EXACT [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex + +[Term] +id: GO:0000419 +name: RNA polymerase V complex +namespace: cellular_component +alt_id: GO:0080137 +def: "RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits." [GOC:krc, GOC:mtg_sensu, PMID:16140984, PMID:19110459] +synonym: "DNA-directed RNA polymerase IVb complex" EXACT [] +synonym: "DNA-directed RNA polymerase V complex" EXACT [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex + +[Term] +id: GO:0000421 +name: autophagosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered." [GOC:autophagy, GOC:isa_complete] +synonym: "autophagic vacuole membrane" EXACT [GOC:autophagy] +is_a: GO:0005774 ! vacuolar membrane +relationship: part_of GO:0005776 ! autophagosome + +[Term] +id: GO:0000422 +name: autophagy of mitochondrion +namespace: biological_process +def: "The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions." [GOC:autophagy, PMID:15798367, PMID:19289147, PMID:23065344] +synonym: "mitochondrion autophagy" EXACT [GOC:autophagy] +synonym: "mitophagy" RELATED [] +xref: Wikipedia:Autophagy_(cellular)#Selective_autophagy +xref: Wikipedia:Mitophagy +is_a: GO:0006914 ! autophagy +is_a: GO:0061726 ! mitochondrion disassembly + +[Term] +id: GO:0000423 +name: mitophagy +namespace: biological_process +def: "The selective autophagy process in which a mitochondrion is degraded by macroautophagy." [PMID:15798367] +comment: Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes. +synonym: "macromitophagy" EXACT [] +is_a: GO:0000422 ! autophagy of mitochondrion +is_a: GO:0061912 ! selective autophagy + +[Term] +id: GO:0000424 +name: micromitophagy +namespace: biological_process +def: "Degradation of a mitochondrion by lysosomal microautophagy." [PMID:15798367, PMID:27003723] +comment: Note that this term is not a child of mitophagy because the community genrally uses that latter to refer to the macroautophagy of mitochondria. +is_a: GO:0000422 ! autophagy of mitochondrion +is_a: GO:0016237 ! lysosomal microautophagy + +[Term] +id: GO:0000425 +name: pexophagy +namespace: biological_process +def: "The selective autophagy process in which a peroxisome is degraded by macroautophagy." [GOC:autophagy, PMID:12914914, PMID:16973210] +synonym: "macropexophagy" EXACT [] +is_a: GO:0030242 ! autophagy of peroxisome +is_a: GO:0061912 ! selective autophagy + +[Term] +id: GO:0000426 +name: micropexophagy +namespace: biological_process +def: "Degradation of a peroxisome by lysosomal microautophagy." [GOC:autophagy, GOC:pad, PMID:12914914, PMID:15350980, PMID:16973210] +comment: Note that this term is not a child of pexophagy because the community usually uses the latter to refer to the macroautohagy process. +is_a: GO:0016237 ! lysosomal microautophagy +is_a: GO:0030242 ! autophagy of peroxisome + +[Term] +id: GO:0000427 +name: plastid-encoded plastid RNA polymerase complex +namespace: cellular_component +def: "An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition." [GOC:krc, GOC:mah, GOC:pj] +is_a: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0000428 +name: DNA-directed RNA polymerase complex +namespace: cellular_component +def: "A protein complex that possesses DNA-directed RNA polymerase activity." [GOC:krc] +is_a: GO:0030880 ! RNA polymerase complex + +[Term] +id: GO:0000429 +name: carbon catabolite regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:krc, GOC:mah] +synonym: "regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0045990 ! carbon catabolite regulation of transcription + +[Term] +id: GO:0000430 +name: regulation of transcription from RNA polymerase II promoter by glucose +namespace: biological_process +def: "Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] +is_a: GO:0000429 ! carbon catabolite regulation of transcription from RNA polymerase II promoter +is_a: GO:0046015 ! regulation of transcription by glucose + +[Term] +id: GO:0000431 +name: regulation of transcription from RNA polymerase II promoter by galactose +namespace: biological_process +def: "Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] +is_a: GO:0000409 ! regulation of transcription by galactose +is_a: GO:0000429 ! carbon catabolite regulation of transcription from RNA polymerase II promoter + +[Term] +id: GO:0000432 +name: positive regulation of transcription from RNA polymerase II promoter by glucose +namespace: biological_process +def: "Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc] +synonym: "activation of transcription from RNA polymerase II promoter by glucose" NARROW [] +synonym: "stimulation of transcription from RNA polymerase II promoter by glucose" NARROW [] +synonym: "up regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +synonym: "up-regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +synonym: "upregulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +is_a: GO:0000430 ! regulation of transcription from RNA polymerase II promoter by glucose +is_a: GO:0000436 ! carbon catabolite activation of transcription from RNA polymerase II promoter +is_a: GO:0046016 ! positive regulation of transcription by glucose + +[Term] +id: GO:0000433 +name: carbon catabolite repression of transcription from RNA polymerase II promoter by glucose +namespace: biological_process +def: "A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances." [GOC:krc] +synonym: "down regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +synonym: "downregulation of transcription from RNA polymerase II promoter by glucose" EXACT [] +synonym: "inhibition of transcription from RNA polymerase II promoter by glucose" NARROW [] +is_a: GO:0045014 ! carbon catabolite repression of transcription by glucose +is_a: GO:0061987 ! negative regulation of transcription from RNA polymerase II promoter by glucose + +[Term] +id: GO:0000434 +name: carbon catabolite repression of transcription from RNA polymerase II promoter by galactose +namespace: biological_process +def: "Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:krc] +synonym: "down regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +synonym: "downregulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +synonym: "inhibition of transcription from RNA polymerase II promoter by galactose" NARROW [] +is_a: GO:0000410 ! carbon catabolite repression of transcription by galactose +is_a: GO:0000431 ! regulation of transcription from RNA polymerase II promoter by galactose +is_a: GO:0000437 ! carbon catabolite repression of transcription from RNA polymerase II promoter + +[Term] +id: GO:0000435 +name: positive regulation of transcription from RNA polymerase II promoter by galactose +namespace: biological_process +def: "Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc] +synonym: "activation of transcription from RNA polymerase II promoter by galactose" NARROW [] +synonym: "stimulation of transcription from RNA polymerase II promoter by galactose" NARROW [] +synonym: "up regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +synonym: "up-regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +synonym: "upregulation of transcription from RNA polymerase II promoter by galactose" EXACT [] +is_a: GO:0000411 ! positive regulation of transcription by galactose +is_a: GO:0000431 ! regulation of transcription from RNA polymerase II promoter by galactose +is_a: GO:0000436 ! carbon catabolite activation of transcription from RNA polymerase II promoter + +[Term] +id: GO:0000436 +name: carbon catabolite activation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] +synonym: "positive regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0000429 ! carbon catabolite regulation of transcription from RNA polymerase II promoter +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0045991 ! carbon catabolite activation of transcription + +[Term] +id: GO:0000437 +name: carbon catabolite repression of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:krc] +synonym: "negative regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0000429 ! carbon catabolite regulation of transcription from RNA polymerase II promoter +is_a: GO:0045013 ! carbon catabolite repression of transcription + +[Term] +id: GO:0000438 +name: core TFIIH complex portion of holo TFIIH complex +namespace: cellular_component +alt_id: GO:0000443 +def: "The core TFIIH complex when it is part of the general transcription factor TFIIH." [GOC:ew, GOC:krc, PMID:14500720, PMID:22308316, PMID:22572993, PMID:7813015] +synonym: "SSL2-core TFIIH complex portion of holo TFIIH complex" EXACT [] +is_a: GO:0000439 ! transcription factor TFIIH core complex +intersection_of: GO:0000439 ! transcription factor TFIIH core complex +intersection_of: part_of GO:0005675 ! transcription factor TFIIH holo complex +relationship: part_of GO:0005675 ! transcription factor TFIIH holo complex + +[Term] +id: GO:0000439 +name: transcription factor TFIIH core complex +namespace: cellular_component +alt_id: GO:0000441 +def: "The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD." [GOC:ew, GOC:krc, PMID:14500720, PMID:17215295, PMID:22308316, PMID:22572993, PMID:23028141, PMID:7813015] +subset: goslim_pir +synonym: "core TFIIH complex" EXACT [] +synonym: "SSL2-core TFIIH complex" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000440 +name: core TFIIH complex portion of NEF3 complex +namespace: cellular_component +alt_id: GO:0000442 +def: "The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3)." [GOC:ew, GOC:krc, PMID:14500720, PMID:22308316, PMID:22572993, PMID:7813015] +synonym: "SSL2-core TFIIH complex portion of NEF3 complex" EXACT [] +is_a: GO:0000439 ! transcription factor TFIIH core complex +intersection_of: GO:0000439 ! transcription factor TFIIH core complex +intersection_of: part_of GO:0000112 ! nucleotide-excision repair factor 3 complex +relationship: part_of GO:0000112 ! nucleotide-excision repair factor 3 complex + +[Term] +id: GO:0000444 +name: MIS12/MIND type complex +namespace: cellular_component +def: "A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1." [GOC:krc, PMID:14633972, PMID:16585270] +synonym: "Mis12 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000777 ! condensed chromosome kinetochore + +[Term] +id: GO:0000445 +name: THO complex part of transcription export complex +namespace: cellular_component +def: "The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits." [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072] +synonym: "THO complex part of TREX complex" EXACT [] +is_a: GO:0000347 ! THO complex +intersection_of: GO:0000347 ! THO complex +intersection_of: part_of GO:0000346 ! transcription export complex +relationship: part_of GO:0000346 ! transcription export complex + +[Term] +id: GO:0000446 +name: nucleoplasmic THO complex +namespace: cellular_component +def: "The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits." [GOC:krc, GOC:se, PMID:11060033, PMID:11979277, PMID:16983072] +is_a: GO:0000347 ! THO complex +is_a: GO:0008023 ! transcription elongation factor complex + +[Term] +id: GO:0000447 +name: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410] +synonym: "endonucleolytic cleavage at A2" NARROW [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000462 ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000466 ! maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000448 +name: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +alt_id: GO:0000490 +def: "Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410] +synonym: "cleavage at C2" RELATED [] +synonym: "cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" EXACT [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000463 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000466 ! maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000449 +name: endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) +namespace: biological_process +def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0000478 ! endonucleolytic cleavage involved in rRNA processing + +[Term] +id: GO:0000450 +name: cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species." [GOC:curators] +is_a: GO:0000478 ! endonucleolytic cleavage involved in rRNA processing + +[Term] +id: GO:0000451 +name: rRNA 2'-O-methylation +namespace: biological_process +def: "The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis." [GOC:curators, ISBN:1555811337] +is_a: GO:0031167 ! rRNA methylation + +[Term] +id: GO:0000452 +name: snoRNA guided rRNA 2'-O-methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation." [GOC:curators, ISBN:1555811337] +synonym: "snoRNA guided rRNA 2'-O-ribose methylation" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0000451 ! rRNA 2'-O-methylation + +[Term] +id: GO:0000453 +name: enzyme-directed rRNA 2'-O-methylation +namespace: biological_process +def: "The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA." [GOC:curators, ISBN:1555811337] +is_a: GO:0000451 ! rRNA 2'-O-methylation + +[Term] +id: GO:0000454 +name: snoRNA guided rRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation." [GOC:curators, ISBN:1555811337] +is_a: GO:0031118 ! rRNA pseudouridine synthesis + +[Term] +id: GO:0000455 +name: enzyme-directed rRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA." [GOC:curators, ISBN:1555811337] +is_a: GO:0031118 ! rRNA pseudouridine synthesis + +[Term] +id: GO:0000456 +name: obsolete dimethylation involved in SSU-rRNA maturation +namespace: biological_process +def: "OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes." [GOC:curators, GOC:dph, GOC:tb, ISBN:1555811337] +comment: The reason for obsoletion is that this term can be captured as a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0000457 +name: endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) +namespace: biological_process +def: "Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0000449 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) +relationship: part_of GO:0002108 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) +relationship: part_of GO:0002109 ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) + +[Term] +id: GO:0000458 +name: endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) +namespace: biological_process +def: "Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0000449 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) +relationship: part_of GO:0002108 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) + +[Term] +id: GO:0000459 +name: exonucleolytic trimming involved in rRNA processing +namespace: biological_process +def: "Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule." [GOC:curators] +synonym: "exonucleolytic trimming during rRNA processing" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000469 ! cleavage involved in rRNA processing +is_a: GO:0090503 ! RNA phosphodiester bond hydrolysis, exonucleolytic +intersection_of: GO:0090503 ! RNA phosphodiester bond hydrolysis, exonucleolytic +intersection_of: part_of GO:0006364 ! rRNA processing + +[Term] +id: GO:0000460 +name: maturation of 5.8S rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule." [GOC:curators] +is_a: GO:0006364 ! rRNA processing + +[Term] +id: GO:0000461 +name: endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA." [GOC:krc, PMID:10690410] +synonym: "endonucleolytic cleavage at site D" NARROW [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +is_a: GO:0031125 ! rRNA 3'-end processing +relationship: part_of GO:0000462 ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000462 +name: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +alt_id: GO:1990041 +def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators] +synonym: "maturation of 18S rRNA" NARROW [] +is_a: GO:0030490 ! maturation of SSU-rRNA + +[Term] +id: GO:0000463 +name: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000470 ! maturation of LSU-rRNA + +[Term] +id: GO:0000464 +name: endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs." [GOC:krc, PMID:10690410] +synonym: "endonucleolytic cleavage at A3" NARROW [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000463 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000466 ! maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000465 +name: exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410] +is_a: GO:0000459 ! exonucleolytic trimming involved in rRNA processing +is_a: GO:0000967 ! rRNA 5'-end processing +relationship: part_of GO:0000466 ! maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000466 +name: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410] +is_a: GO:0000460 ! maturation of 5.8S rRNA + +[Term] +id: GO:0000467 +name: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410] +is_a: GO:0000459 ! exonucleolytic trimming involved in rRNA processing +is_a: GO:0031125 ! rRNA 3'-end processing +relationship: part_of GO:0000466 ! maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000468 +name: generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410] +synonym: "processing at B2" NARROW [] +is_a: GO:0031125 ! rRNA 3'-end processing +relationship: part_of GO:0000463 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000469 +name: cleavage involved in rRNA processing +namespace: biological_process +def: "Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule." [GOC:curators] +synonym: "cleavage during rRNA processing" RELATED [GOC:dph, GOC:tb] +is_a: GO:0090501 ! RNA phosphodiester bond hydrolysis +intersection_of: GO:0090501 ! RNA phosphodiester bond hydrolysis +intersection_of: part_of GO:0006364 ! rRNA processing +relationship: part_of GO:0006364 ! rRNA processing + +[Term] +id: GO:0000470 +name: maturation of LSU-rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule." [GOC:curators] +is_a: GO:0006364 ! rRNA processing +relationship: part_of GO:0042273 ! ribosomal large subunit biogenesis + +[Term] +id: GO:0000471 +name: endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events." [GOC:krc, PMID:10690410] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000472 +name: endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA." [GOC:curators, PMID:10690410] +synonym: "endonucleolytic cleavage at A1" NARROW [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +is_a: GO:0000967 ! rRNA 5'-end processing +relationship: part_of GO:0000462 ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000473 +name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000470 ! maturation of LSU-rRNA + +[Term] +id: GO:0000474 +name: maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0030490 ! maturation of SSU-rRNA + +[Term] +id: GO:0000475 +name: maturation of 2S rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule." [GOC:curators] +is_a: GO:0006364 ! rRNA processing + +[Term] +id: GO:0000476 +name: maturation of 4.5S rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule." [GOC:curators] +is_a: GO:0006364 ! rRNA processing + +[Term] +id: GO:0000477 +name: generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410] +synonym: "processing at C1" NARROW [] +is_a: GO:0000469 ! cleavage involved in rRNA processing +is_a: GO:0000967 ! rRNA 5'-end processing +relationship: part_of GO:0000463 ! maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000478 +name: endonucleolytic cleavage involved in rRNA processing +namespace: biological_process +def: "Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA." [GOC:krc, PMID:10690410] +synonym: "endonucleolytic cleavage during rRNA processing" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000469 ! cleavage involved in rRNA processing +is_a: GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic +intersection_of: GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic +intersection_of: part_of GO:0006364 ! rRNA processing + +[Term] +id: GO:0000479 +name: endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae." [GOC:curators, PMID:10690410] +is_a: GO:0000478 ! endonucleolytic cleavage involved in rRNA processing + +[Term] +id: GO:0000480 +name: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable." [GOC:curators, PMID:10690410, PMID:15282326] +synonym: "endonucleolytic cleavage at A-prime" NARROW [PMID:15282326] +synonym: "endonucleolytic cleavage at A0" NARROW [] +is_a: GO:0000479 ! endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +relationship: part_of GO:0000462 ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + +[Term] +id: GO:0000481 +name: maturation of 5S rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule." [GOC:curators] +is_a: GO:0006364 ! rRNA processing + +[Term] +id: GO:0000482 +name: maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000481 ! maturation of 5S rRNA + +[Term] +id: GO:0000483 +name: endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species." [GOC:curators] +is_a: GO:0000478 ! endonucleolytic cleavage involved in rRNA processing + +[Term] +id: GO:0000484 +name: cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000483 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +relationship: part_of GO:0000474 ! maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +relationship: part_of GO:0000487 ! maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) + +[Term] +id: GO:0000485 +name: cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:768488] +is_a: GO:0000483 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +relationship: part_of GO:0000473 ! maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +relationship: part_of GO:0000475 ! maturation of 2S rRNA + +[Term] +id: GO:0000486 +name: cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:768488] +is_a: GO:0000483 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +relationship: part_of GO:0000475 ! maturation of 2S rRNA +relationship: part_of GO:0000487 ! maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) + +[Term] +id: GO:0000487 +name: maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000460 ! maturation of 5.8S rRNA + +[Term] +id: GO:0000488 +name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000470 ! maturation of LSU-rRNA + +[Term] +id: GO:0000489 +name: maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0030490 ! maturation of SSU-rRNA + +[Term] +id: GO:0000491 +name: small nucleolar ribonucleoprotein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex." [GOC:krc] +synonym: "snoRNP assembly" EXACT [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly + +[Term] +id: GO:0000492 +name: box C/D snoRNP assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex." [GOC:krc] +synonym: "box C/D small nucleolar ribonucleoprotein complex assembly" EXACT [] +is_a: GO:0000491 ! small nucleolar ribonucleoprotein complex assembly + +[Term] +id: GO:0000493 +name: box H/ACA snoRNP assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex." [GOC:krc, PMID:12515383] +synonym: "box H/ACA small nucleolar ribonucleoprotein complex assembly" EXACT [] +is_a: GO:0000491 ! small nucleolar ribonucleoprotein complex assembly + +[Term] +id: GO:0000494 +name: box C/D snoRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a box C/D snoRNA molecule." [GOC:krc] +synonym: "box C/D snoRNA 3' end processing" EXACT [] +is_a: GO:0031126 ! snoRNA 3'-end processing +is_a: GO:0034963 ! box C/D snoRNA processing + +[Term] +id: GO:0000495 +name: box H/ACA snoRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a box H/ACA snoRNA molecule." [GOC:krc] +synonym: "box H/ACA snoRNA 3' end processing" EXACT [] +is_a: GO:0031126 ! snoRNA 3'-end processing +is_a: GO:0034964 ! box H/ACA snoRNA processing + +[Term] +id: GO:0000497 +name: DNA template activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule." [GOC:krc] +comment: Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with DNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. +synonym: "base pairing with DNA" RELATED [] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0000500 +name: RNA polymerase I upstream activating factor complex +namespace: cellular_component +def: "A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p." [PMID:11500378] +synonym: "RNA polymerase I upstream activation factor complex" EXACT [] +synonym: "UAF" EXACT [] +is_a: GO:0000120 ! RNA polymerase I transcription regulator complex + +[Term] +id: GO:0000502 +name: proteasome complex +namespace: cellular_component +def: "A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core." [GOC:rb, Wikipedia:Proteasome] +subset: goslim_pir +synonym: "26S proteasome" NARROW [] +synonym: "proteasome" EXACT [GOC:cjm] +is_a: GO:1905369 ! endopeptidase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0000504 +name: obsolete proteasome regulatory particle (sensu Bacteria) +namespace: cellular_component +def: "OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2)." [GOC:rb] +comment: This term was made obsolete because there is no ubiquitin in bacteria and they do not have proteasome regulatory particles. Instead they have proteasome-activating nucleotidase. +synonym: "26S proteasome" NARROW [] +synonym: "proteasome regulatory particle (sensu Bacteria)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000506 +name: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast." [GOC:kp, GOC:rb, PMID:10944123, PMID:15163411] +comment: Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity. +synonym: "GPI-GlcNAc transferase complex" EXACT [] +synonym: "GPI-GnT complex" EXACT [] +synonym: "GPI-N-acetylglucosaminyltransferase complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0000578 +name: embryonic axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb] +synonym: "embryonic axis determination" RELATED [] +is_a: GO:0009798 ! axis specification +is_a: GO:0009880 ! embryonic pattern specification + +[Term] +id: GO:0000700 +name: mismatch base pair DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:9224623] +is_a: GO:0019104 ! DNA N-glycosylase activity + +[Term] +id: GO:0000701 +name: purine-specific mismatch base pair DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site." [GOC:elh, PMID:9224623] +synonym: "A/G-specific adenine DNA glycosylase activity" NARROW [] +xref: EC:3.2.2 +is_a: GO:0000700 ! mismatch base pair DNA N-glycosylase activity + +[Term] +id: GO:0000702 +name: oxidized base lesion DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:11554296] +is_a: GO:0019104 ! DNA N-glycosylase activity + +[Term] +id: GO:0000703 +name: oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity +namespace: molecular_function +alt_id: GO:0019004 +def: "Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site." [GOC:elh, PMID:11554296] +comment: Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'. +synonym: "bifunctional DNA glycosylase" BROAD [] +synonym: "DNA glycosylase/AP-lyase" BROAD [] +synonym: "DNA glycosylase/beta-lyase" BROAD [] +synonym: "endodeoxyribonuclease III" RELATED [] +synonym: "endonuclease III" RELATED [] +synonym: "endonuclease VIII activity" RELATED [] +synonym: "oxidized pyrimidine base lesion DNA N-glycosylase activity" EXACT [GOC:go_curators] +synonym: "pyrimidine-specific oxidized base lesion DNA N-glycosylase activity" RELATED [] +xref: Reactome:R-HSA-110224 "Cleavage of thymine glycol by NTHL1 glycosylase" +xref: Reactome:R-HSA-110226 "Cleavage of cytosine glycol by NTHL1 glycosylase" +xref: Reactome:R-HSA-110227 "Cleavage of dihydrouracil by NTHL1 glycosylase" +is_a: GO:0000702 ! oxidized base lesion DNA N-glycosylase activity + +[Term] +id: GO:0000704 +name: pyrimidine dimer DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site." [GOC:elh, PMID:9224623] +is_a: GO:0019104 ! DNA N-glycosylase activity + +[Term] +id: GO:0000705 +name: achiasmate meiosis I +namespace: biological_process +def: "The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata." [GOC:elh, GOC:sart, PMID:10690419] +synonym: "achiasmate meiosis I nuclear division" EXACT [] +is_a: GO:0007127 ! meiosis I + +[Term] +id: GO:0000706 +name: meiotic DNA double-strand break processing +namespace: biological_process +def: "The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis." [GOC:elh, PMID:9334324] +is_a: GO:0000729 ! DNA double-strand break processing +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0000729 ! DNA double-strand break processing +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0000707 +name: meiotic DNA recombinase assembly +namespace: biological_process +def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA." [GOC:elh, PMID:11459983] +is_a: GO:0000730 ! DNA recombinase assembly +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0000708 +name: meiotic strand invasion +namespace: biological_process +def: "The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis." [GOC:elh, PMID:10915877] +synonym: "meiotic D-loop biosynthesis" RELATED [] +synonym: "meiotic D-loop formation" RELATED [] +synonym: "meiotic displacement loop biosynthesis" RELATED [GOC:mah, GOC:vw] +synonym: "meiotic displacement loop formation" RELATED [GOC:mah, GOC:vw] +is_a: GO:0042148 ! strand invasion +is_a: GO:0061982 ! meiosis I cell cycle process +intersection_of: GO:0042148 ! strand invasion +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0000709 +name: meiotic joint molecule formation +namespace: biological_process +def: "The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA." [GOC:elh, PMID:8521495] +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0000710 +name: meiotic mismatch repair +namespace: biological_process +def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855] +is_a: GO:0006298 ! mismatch repair +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0000711 +name: meiotic DNA repair synthesis +namespace: biological_process +def: "During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template." [GOC:elh, PMID:9334324] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0000712 +name: resolution of meiotic recombination intermediates +namespace: biological_process +def: "The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, PMID:11733053] +synonym: "resolution of meiotic joint molecules as recombinants" NARROW [GOC:elh, GOC:mah] +is_a: GO:0061982 ! meiosis I cell cycle process +relationship: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0051307 ! meiotic chromosome separation + +[Term] +id: GO:0000713 +name: meiotic heteroduplex formation +namespace: biological_process +def: "During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:9334324] +is_a: GO:0061982 ! meiosis I cell cycle process +relationship: part_of GO:0006310 ! DNA recombination + +[Term] +id: GO:0000714 +name: meiotic strand displacement +namespace: biological_process +def: "The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis." [GOC:elh, PMID:10357855] +synonym: "meiotic D-loop dissociation" RELATED [GOC:mah, GOC:vw] +synonym: "meiotic D-loop processing" RELATED [GOC:mah, GOC:vw] +synonym: "meiotic displacement loop dissociation" RELATED [GOC:mah, GOC:vw] +synonym: "meiotic displacement loop processing" RELATED [GOC:mah, GOC:vw] +is_a: GO:0000732 ! strand displacement +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0000715 +name: nucleotide-excision repair, DNA damage recognition +namespace: biological_process +def: "The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix." [GOC:elh, PMID:10197977] +synonym: "pyrimidine-dimer repair, DNA damage recognition" RELATED [] +is_a: GO:0051276 ! chromosome organization +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0000716 +name: transcription-coupled nucleotide-excision repair, DNA damage recognition +namespace: biological_process +def: "The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway." [GOC:elh, PMID:10197977] +synonym: "pyrimidine-dimer repair, DNA damage recognition" RELATED [] +is_a: GO:0000715 ! nucleotide-excision repair, DNA damage recognition +relationship: part_of GO:0006283 ! transcription-coupled nucleotide-excision repair + +[Term] +id: GO:0000717 +name: nucleotide-excision repair, DNA duplex unwinding +namespace: biological_process +def: "The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage." [GOC:elh, PMID:10197977] +is_a: GO:0032508 ! DNA duplex unwinding +intersection_of: GO:0032508 ! DNA duplex unwinding +intersection_of: part_of GO:0006289 ! nucleotide-excision repair +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0000718 +name: nucleotide-excision repair, DNA damage removal +namespace: biological_process +def: "The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage." [GOC:elh, PMID:10197977] +is_a: GO:0044349 ! DNA excision +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0000719 +name: photoreactive repair +namespace: biological_process +def: "The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines." [GOC:elh, PMID:10915863] +synonym: "pyrimidine-dimer repair by photolyase" NARROW [] +is_a: GO:0006290 ! pyrimidine dimer repair + +[Term] +id: GO:0000720 +name: pyrimidine dimer repair by nucleotide-excision repair +namespace: biological_process +def: "The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase." [GOC:elh] +comment: Note that the repair of pyrimidine dimers by nucleotide excision repair involves the same gene products that are involved in general nucleotide excision repair. Consider also annotating to other children of the biological process term 'nucleotide-excision repair ; GO:0006289'. +is_a: GO:0006289 ! nucleotide-excision repair +is_a: GO:0006290 ! pyrimidine dimer repair + +[Term] +id: GO:0000721 +name: (R,R)-butanediol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+)." [EC:1.1.1.4] +synonym: "(R)-2,3-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "(R)-diacetyl reductase activity" EXACT [EC:1.1.1.4] +synonym: "1-amino-2-propanol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "1-amino-2-propanol oxidoreductase activity" EXACT [EC:1.1.1.4] +synonym: "2,3-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "aminopropanol oxidoreductase activity" EXACT [EC:1.1.1.4] +synonym: "butylene glycol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "butyleneglycol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "D-(-)-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "D-1-amino-2-propanol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "D-1-amino-2-propanol:NAD(2) oxidoreductase activity" EXACT [EC:1.1.1.4] +synonym: "D-aminopropanol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "D-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] +synonym: "diacetyl (acetoin) reductase activity" RELATED [EC:1.1.1.4] +xref: EC:1.1.1.4 +xref: MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN +xref: RHEA:24340 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0000722 +name: telomere maintenance via recombination +namespace: biological_process +def: "Any recombinational process that contributes to the maintenance of proper telomeric length." [GOC:elh, PMID:11850777] +synonym: "telomerase-independent telomere maintenance" RELATED [] +is_a: GO:0000723 ! telomere maintenance +is_a: GO:0006312 ! mitotic recombination + +[Term] +id: GO:0000723 +name: telomere maintenance +namespace: biological_process +def: "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences." [GOC:BHF, GOC:BHF_telomere, GOC:elh, GOC:rl, PMID:11092831] +synonym: "regulation of telomere length" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0032200 ! telomere organization +is_a: GO:0060249 ! anatomical structure homeostasis + +[Term] +id: GO:0000724 +name: double-strand break repair via homologous recombination +namespace: biological_process +alt_id: GO:0016924 +def: "The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule." [GOC:elh, PMID:10357855] +synonym: "HDR" EXACT [GOC:vk] +synonym: "homologous recombinational repair" EXACT [] +synonym: "homology-directed repair" EXACT [GOC:vk] +synonym: "HRR" EXACT [] +synonym: "Rad51-dependent recombinational repair" EXACT [GOC:mah] +synonym: "Rhp51-dependent recombinational repair" EXACT [] +is_a: GO:0000725 ! recombinational repair +is_a: GO:0006302 ! double-strand break repair + +[Term] +id: GO:0000725 +name: recombinational repair +namespace: biological_process +def: "A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA." [GOC:elh] +xref: Wikipedia:Recombinational_repair +is_a: GO:0006281 ! DNA repair +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0000726 +name: non-recombinational repair +namespace: biological_process +def: "A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous region of DNA." [GOC:elh] +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0000727 +name: double-strand break repair via break-induced replication +namespace: biological_process +def: "The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome." [GOC:elh, PMID:10357855] +is_a: GO:0000724 ! double-strand break repair via homologous recombination + +[Term] +id: GO:0000728 +name: gene conversion at mating-type locus, DNA double-strand break formation +namespace: biological_process +def: "The site-specific endonucleolytic cleavage of DNA at the mating-type locus which initiates the conversion of one mating-type allele to another." [GOC:elh, PMID:7646483] +is_a: GO:0022414 ! reproductive process +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0000729 +name: DNA double-strand break processing +namespace: biological_process +def: "The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang." [PMID:10357855] +is_a: GO:0006259 ! DNA metabolic process +relationship: has_part GO:0035312 ! 5'-3' exodeoxyribonuclease activity +relationship: part_of GO:0006302 ! double-strand break repair + +[Term] +id: GO:0000730 +name: DNA recombinase assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA." [PMID:10357855] +synonym: "Rad51 nucleoprotein filament formation" EXACT [GOC:elh, GOC:vw] +is_a: GO:0065004 ! protein-DNA complex assembly +is_a: GO:0090735 ! DNA repair complex assembly +relationship: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing + +[Term] +id: GO:0000731 +name: DNA synthesis involved in DNA repair +namespace: biological_process +def: "Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template." [PMID:10357855] +synonym: "DNA repair synthesis" BROAD [] +synonym: "DNA synthesis during DNA repair" RELATED [GOC:dph, GOC:tb] +synonym: "mitotic DNA repair synthesis" NARROW [GOC:mah] +is_a: GO:0071897 ! DNA biosynthetic process +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:0006281 ! DNA repair +relationship: part_of GO:0006281 ! DNA repair + +[Term] +id: GO:0000732 +name: strand displacement +namespace: biological_process +def: "The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules." [PMID:10357855] +synonym: "D-loop dissociation" RELATED [GOC:mah, GOC:vw] +synonym: "D-loop processing" RELATED [GOC:mah, GOC:vw] +synonym: "displacement loop dissociation" RELATED [GOC:mah, GOC:vw] +synonym: "displacement loop processing" RELATED [GOC:mah, GOC:vw] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006310 ! DNA recombination + +[Term] +id: GO:0000733 +name: DNA strand renaturation +namespace: biological_process +def: "The identification and annealing of complementary base pairs in single-strand DNA." [GOC:elh] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0032392 ! DNA geometric change + +[Term] +id: GO:0000734 +name: gene conversion at mating-type locus, DNA repair synthesis +namespace: biological_process +def: "Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template during gene conversion at the mating-type locus." [GOC:elh] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0000731 ! DNA synthesis involved in DNA repair +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0000735 +name: removal of nonhomologous ends +namespace: biological_process +def: "The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur." [PMID:10357855] +is_a: GO:0006259 ! DNA metabolic process +relationship: has_part GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0000736 +name: double-strand break repair via single-strand annealing, removal of nonhomologous ends +namespace: biological_process +def: "During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur." [PMID:10357855] +is_a: GO:0000735 ! removal of nonhomologous ends +intersection_of: GO:0000735 ! removal of nonhomologous ends +intersection_of: part_of GO:0045002 ! double-strand break repair via single-strand annealing +relationship: part_of GO:0045002 ! double-strand break repair via single-strand annealing + +[Term] +id: GO:0000737 +name: DNA catabolic process, endonucleolytic +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides." [GOC:elh, GOC:mah] +synonym: "DNA breakdown, endonucleolytic" EXACT [] +synonym: "DNA degradation, endonucleolytic" EXACT [] +synonym: "endonucleolytic degradation of DNA" EXACT [] +synonym: "endonucleolytic DNA catabolism" EXACT [] +is_a: GO:0006308 ! DNA catabolic process +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +relationship: has_part GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0000738 +name: DNA catabolic process, exonucleolytic +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides." [GOC:elh, GOC:mah] +synonym: "DNA breakdown, exonucleolytic" EXACT [] +synonym: "DNA degradation, exonucleolytic" EXACT [] +synonym: "exonucleolytic degradation of DNA" EXACT [] +is_a: GO:0006308 ! DNA catabolic process +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +relationship: has_part GO:0004529 ! exodeoxyribonuclease activity + +[Term] +id: GO:0000739 +name: obsolete DNA strand annealing activity +namespace: molecular_function +def: "OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA." [GOC:elh] +comment: This term was made obsolete because it describes a process and not an activity. +synonym: "DNA strand annealing activity" EXACT [] +is_obsolete: true +consider: GO:0000733 +consider: GO:0036292 +consider: GO:0036310 + +[Term] +id: GO:0000740 +name: nuclear membrane fusion +namespace: biological_process +def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh] +is_a: GO:0090174 ! organelle membrane fusion + +[Term] +id: GO:0000741 +name: karyogamy +namespace: biological_process +alt_id: GO:0007335 +def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh] +synonym: "nuclear fusion" EXACT [] +synonym: "nuclear fusion during karyogamy" EXACT [] +xref: Wikipedia:Karyogamy +is_a: GO:0048284 ! organelle fusion +relationship: part_of GO:0006997 ! nucleus organization + +[Term] +id: GO:0000742 +name: karyogamy involved in conjugation with cellular fusion +namespace: biological_process +def: "During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy." [GOC:elh] +synonym: "karyogamy during conjugation with cellular fusion" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000741 ! karyogamy +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0000741 ! karyogamy +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0000743 +name: nuclear migration involved in conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0006946 +def: "The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion." [GOC:clt, GOC:vw, PMID:16380440] +synonym: "nuclear congression" EXACT [GOC:vw] +synonym: "nuclear migration during conjugation with cellular fusion" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022414 ! reproductive process +is_a: GO:0030473 ! nuclear migration along microtubule +intersection_of: GO:0007097 ! nuclear migration +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0000744 +name: karyogamy involved in conjugation with mutual genetic exchange +namespace: biological_process +def: "During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena." [GOC:mah, GOC:pg] +synonym: "karyogamy involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +is_a: GO:0000741 ! karyogamy +intersection_of: GO:0000741 ! karyogamy +intersection_of: part_of GO:0000748 ! conjugation with mutual genetic exchange +relationship: part_of GO:0000748 ! conjugation with mutual genetic exchange +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16248 xsd:anyURI + +[Term] +id: GO:0000745 +name: nuclear migration involved in conjugation with mutual genetic exchange +namespace: biological_process +def: "The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion." [GOC:clt, GOC:mah] +synonym: "nuclear exchange during conjugation without cellular fusion" RELATED [] +synonym: "nuclear migration involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007097 ! nuclear migration +intersection_of: GO:0007097 ! nuclear migration +intersection_of: part_of GO:0000748 ! conjugation with mutual genetic exchange +relationship: part_of GO:0000744 ! karyogamy involved in conjugation with mutual genetic exchange + +[Term] +id: GO:0000746 +name: conjugation +namespace: biological_process +def: "The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms." [GOC:elh] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +subset: goslim_yeast +xref: Wikipedia:Conjugation +is_a: GO:0044764 ! multi-organism cellular process + +[Term] +id: GO:0000747 +name: conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007322 +alt_id: GO:0007333 +alt_id: GO:0030461 +alt_id: GO:0030477 +def: "A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae." [GOC:elh] +subset: goslim_pombe +synonym: "cell fusion" RELATED [] +synonym: "mating" RELATED [] +is_a: GO:0000746 ! conjugation +is_a: GO:0019953 ! sexual reproduction +is_a: GO:0140253 ! cell-cell fusion + +[Term] +id: GO:0000748 +name: conjugation with mutual genetic exchange +namespace: biological_process +def: "A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange." [GOC:elh] +synonym: "conjugation without cellular fusion" EXACT [] +is_a: GO:0000746 ! conjugation + +[Term] +id: GO:0000749 +name: response to pheromone triggering conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007328 +alt_id: GO:0030434 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae." [GOC:clt] +synonym: "response to pheromone during conjugation with cellular fusion" RELATED [GOC:dph] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +is_a: GO:0071444 ! cellular response to pheromone +intersection_of: GO:0019236 ! response to pheromone +intersection_of: positively_regulates GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0000750 +name: pheromone-dependent signal transduction involved in conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007330 +alt_id: GO:0030454 +def: "A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae." [GOC:clt] +synonym: "transduction of mating signal" BROAD [] +is_a: GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion +relationship: part_of GO:0000749 ! response to pheromone triggering conjugation with cellular fusion + +[Term] +id: GO:0000751 +name: mitotic cell cycle G1 arrest in response to pheromone +namespace: biological_process +alt_id: GO:0030571 +def: "The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae." [GOC:clt, GOC:dph, GOC:mah, GOC:tb] +synonym: "cell cycle arrest in response to pheromone" BROAD [] +is_a: GO:0071850 ! mitotic cell cycle arrest +relationship: part_of GO:0000749 ! response to pheromone triggering conjugation with cellular fusion + +[Term] +id: GO:0000752 +name: agglutination involved in conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007334 +def: "The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae." [GOC:elh] +synonym: "agglutination" BROAD [] +synonym: "cell-cell adhesion during conjugation with cellular fusion" EXACT [] +synonym: "cell-cell adhesion during mating" EXACT [] +is_a: GO:0000771 ! agglutination involved in conjugation +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000749 ! response to pheromone triggering conjugation with cellular fusion + +[Term] +id: GO:0000753 +name: cell morphogenesis involved in conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007332 +def: "The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion." [GOC:clt] +synonym: "shmoo orientation" NARROW [] +synonym: "shmooing" NARROW [] +is_a: GO:0000767 ! cell morphogenesis involved in conjugation +is_a: GO:0003006 ! developmental process involved in reproduction +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0000754 +name: adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion +namespace: biological_process +alt_id: GO:0007331 +alt_id: GO:0030453 +def: "In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae." [GOC:clt] +synonym: "adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion" EXACT [GOC:mah] +synonym: "adaptation to pheromone during conjugation with cellular fusion" RELATED [GOC:dph, GOC:tb] +synonym: "desensitization to pheromone during conjugation with cellular fusion" EXACT [] +is_a: GO:0023058 ! adaptation of signaling pathway +relationship: part_of GO:0000749 ! response to pheromone triggering conjugation with cellular fusion + +[Term] +id: GO:0000755 +name: cytogamy +namespace: biological_process +alt_id: GO:0000218 +alt_id: GO:0030462 +def: "During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae." [GOC:elh] +synonym: "zygote formation" RELATED [] +is_a: GO:0022413 ! reproductive process in single-celled organism +relationship: part_of GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0000756 +name: response to pheromone regulating conjugation with mutual genetic exchange +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion." [GOC:clt] +synonym: "response to pheromone triggering conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007154 ! cell communication +is_a: GO:0046999 ! regulation of conjugation +is_a: GO:0071444 ! cellular response to pheromone +intersection_of: GO:0019236 ! response to pheromone +intersection_of: regulates GO:0000748 ! conjugation with mutual genetic exchange +relationship: regulates GO:0000748 ! conjugation with mutual genetic exchange + +[Term] +id: GO:0000757 +name: obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange +namespace: biological_process +def: "OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion." [GOC:clt] +comment: This term was obsoleted because its label and definitions were not clear. It had never been used for annotation. +synonym: "signal transduction involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15815 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0000758 +name: agglutination involved in conjugation with mutual genetic exchange +namespace: biological_process +def: "The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism." [GOC:elh] +synonym: "agglutination involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +synonym: "sexual flocculation" EXACT [] +is_a: GO:0000771 ! agglutination involved in conjugation +relationship: part_of GO:0000756 ! response to pheromone regulating conjugation with mutual genetic exchange + +[Term] +id: GO:0000759 +name: cell morphogenesis involved in conjugation with mutual genetic exchange +namespace: biological_process +def: "The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion." [GOC:clt] +synonym: "cellular morphogenesis involved in conjugation without cellular fusion" EXACT [GOC:dph, GOC:tb] +is_a: GO:0000767 ! cell morphogenesis involved in conjugation +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0000748 ! conjugation with mutual genetic exchange +relationship: part_of GO:0000748 ! conjugation with mutual genetic exchange + +[Term] +id: GO:0000760 +name: adaptation to pheromone regulating conjugation with mutual genetic exchange +namespace: biological_process +def: "In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses." [GOC:clt] +synonym: "adaptation to pheromone involved conjugation without cellular fusion" RELATED [GOC:dph, GOC:tb] +synonym: "desensitization to pheromone during conjugation without cellular fusion" EXACT [] +is_a: GO:0000756 ! response to pheromone regulating conjugation with mutual genetic exchange +is_a: GO:0022401 ! negative adaptation of signaling pathway + +[Term] +id: GO:0000761 +name: conjugant formation +namespace: biological_process +def: "During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing." [GOC:elh] +is_a: GO:0000771 ! agglutination involved in conjugation +relationship: part_of GO:0000748 ! conjugation with mutual genetic exchange + +[Term] +id: GO:0000762 +name: pheromone-induced unidirectional conjugation +namespace: biological_process +def: "The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types." [GOC:elh] +is_a: GO:0009291 ! unidirectional conjugation + +[Term] +id: GO:0000763 +name: obsolete cell morphogenesis involved in unidirectional conjugation +namespace: biological_process +def: "OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation." [GOC:clt] +comment: This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur. +synonym: "cell morphogenesis involved in unidirectional conjugation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000764 +name: obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation +namespace: biological_process +def: "OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation." [GOC:clt] +comment: This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur. +synonym: "cellular morphogenesis during pheromone-induced unidirectional" RELATED [GOC:dph, GOC:tb] +synonym: "cellular morphogenesis involved in pheromone-induced unidirectional conjugation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0000765 +name: response to pheromone regulating pheromone-induced unidirectional conjugation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation." [GOC:clt] +synonym: "response to pheromone during pheromone-induced unidirectional" RELATED [GOC:dph, GOC:tb] +is_a: GO:0019236 ! response to pheromone +is_a: GO:0046999 ! regulation of conjugation +intersection_of: GO:0019236 ! response to pheromone +intersection_of: regulates GO:0000762 ! pheromone-induced unidirectional conjugation +relationship: regulates GO:0000762 ! pheromone-induced unidirectional conjugation + +[Term] +id: GO:0000766 +name: negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation +namespace: biological_process +def: "In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses." [GOC:clt] +synonym: "adaptation to pheromone during pheromone-induced unidirectional conjugation" RELATED [GOC:dph, GOC:tb] +synonym: "desensitization to pheromone during pheromone-induced unidirectional conjugation" EXACT [] +synonym: "negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah] +is_a: GO:0022401 ! negative adaptation of signaling pathway +relationship: part_of GO:0000765 ! response to pheromone regulating pheromone-induced unidirectional conjugation + +[Term] +id: GO:0000767 +name: cell morphogenesis involved in conjugation +namespace: biological_process +def: "The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types." [GOC:elh] +is_a: GO:0000902 ! cell morphogenesis +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0000746 ! conjugation +relationship: part_of GO:0000746 ! conjugation + +[Term] +id: GO:0000768 +name: syncytium formation by plasma membrane fusion +namespace: biological_process +def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb] +synonym: "cell fusion" BROAD [] +is_a: GO:0006949 ! syncytium formation +is_a: GO:0140253 ! cell-cell fusion +intersection_of: GO:0006949 ! syncytium formation +intersection_of: has_part GO:0045026 ! plasma membrane fusion + +[Term] +id: GO:0000769 +name: syncytium formation by mitosis without cytokinesis +namespace: biological_process +def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis." [GOC:mah, GOC:tb] +synonym: "syncytium formation by mitosis without cell division" RELATED [GOC:mah] +is_a: GO:0006949 ! syncytium formation +intersection_of: GO:0006949 ! syncytium formation +intersection_of: has_part GO:0033301 ! cell cycle comprising mitosis without cytokinesis +relationship: has_part GO:0033301 ! cell cycle comprising mitosis without cytokinesis + +[Term] +id: GO:0000770 +name: peptide pheromone export +namespace: biological_process +alt_id: GO:0007325 +def: "The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones." [GOC:elh] +synonym: "a-factor export" NARROW [] +is_a: GO:0009914 ! hormone transport +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0000771 +name: agglutination involved in conjugation +namespace: biological_process +def: "The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation." [GOC:elh] +is_a: GO:0051703 ! intraspecies interaction between organisms +is_a: GO:0098610 ! adhesion between unicellular organisms +intersection_of: GO:0098610 ! adhesion between unicellular organisms +intersection_of: part_of GO:0000746 ! conjugation +relationship: part_of GO:0000746 ! conjugation + +[Term] +id: GO:0000772 +name: mating pheromone activity +namespace: molecular_function +def: "The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted." [GOC:clt, GOC:elh] +is_a: GO:0005186 ! pheromone activity + +[Term] +id: GO:0000773 +name: phosphatidyl-N-methylethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine." [EC:2.1.1.71] +synonym: "methyltransferase II" RELATED [EC:2.1.1.71] +synonym: "phosphatidyl-N-methylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] +synonym: "phosphatidyl-N-monomethylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] +synonym: "phosphatidylethanolamine methyltransferase I" RELATED [EC:2.1.1.71] +synonym: "phosphatidylmonomethylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] +synonym: "phospholipid methyltransferase activity" EXACT [EC:2.1.1.71] +synonym: "PLMT" EXACT [] +synonym: "S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.71] +xref: EC:2.1.1.71 +xref: MetaCyc:2.1.1.71-RXN +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0000774 +name: adenyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins." [GOC:kd] +xref: Reactome:R-HSA-5252079 "HSP110s exchange ATP for ADP on HSP70s:ADP" +is_a: GO:0030554 ! adenyl nucleotide binding +is_a: GO:0060590 ! ATPase regulator activity + +[Term] +id: GO:0000775 +name: chromosome, centromeric region +namespace: cellular_component +alt_id: GO:0097521 +def: "The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:cjm, GOC:elh, GOC:kmv, GOC:pr] +comment: Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. +synonym: "centromere" RELATED [] +synonym: "centromere complex" EXACT [] +synonym: "chromosome, centric region" EXACT [] +synonym: "chromosome, pericentric region" RELATED [] +xref: SO:0000577 +is_a: GO:0098687 ! chromosomal region + +[Term] +id: GO:0000776 +name: kinetochore +namespace: cellular_component +alt_id: GO:0005699 +def: "A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GOC:elh] +comment: Note that the kinetochore overlaps the centromeric DNA, but centromeric DNA is not part of the kinetochore. +subset: goslim_pir +xref: Wikipedia:Kinetochore +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +is_a: GO:0099080 ! supramolecular complex +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0000777 +name: condensed chromosome kinetochore +namespace: cellular_component +def: "A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules." [GOC:elh] +is_a: GO:0000776 ! kinetochore +intersection_of: GO:0000776 ! kinetochore +intersection_of: part_of GO:0000793 ! condensed chromosome +relationship: part_of GO:0000779 ! condensed chromosome, centromeric region + +[Term] +id: GO:0000778 +name: condensed nuclear chromosome kinetochore +namespace: cellular_component +def: "A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules." [GOC:elh] +is_a: GO:0000777 ! condensed chromosome kinetochore +intersection_of: GO:0000776 ! kinetochore +intersection_of: part_of GO:0000794 ! condensed nuclear chromosome +relationship: part_of GO:0000780 ! condensed nuclear chromosome, centromeric region + +[Term] +id: GO:0000779 +name: condensed chromosome, centromeric region +namespace: cellular_component +def: "The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:elh, GOC:kmv] +comment: Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. +synonym: "condensed chromosome, centric region" EXACT [] +synonym: "condensed chromosome, centromere" RELATED [] +synonym: "condensed chromosome, pericentric region" RELATED [] +is_a: GO:0000775 ! chromosome, centromeric region +intersection_of: GO:0000775 ! chromosome, centromeric region +intersection_of: part_of GO:0000793 ! condensed chromosome +relationship: part_of GO:0000793 ! condensed chromosome + +[Term] +id: GO:0000780 +name: condensed nuclear chromosome, centromeric region +namespace: cellular_component +def: "The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:elh, GOC:kmv] +comment: Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. +synonym: "condensed nuclear chromosome, centric region" EXACT [] +synonym: "condensed nuclear chromosome, centromere" RELATED [] +synonym: "condensed nuclear chromosome, pericentric region" RELATED [] +is_a: GO:0000779 ! condensed chromosome, centromeric region +intersection_of: GO:0000779 ! condensed chromosome, centromeric region +intersection_of: part_of GO:0000794 ! condensed nuclear chromosome +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0000781 +name: chromosome, telomeric region +namespace: cellular_component +def: "The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins." [GOC:elh] +comment: Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. +synonym: "telomere" RELATED [] +xref: SO:0000624 +is_a: GO:0098687 ! chromosomal region + +[Term] +id: GO:0000782 +name: telomere cap complex +namespace: cellular_component +def: "A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome." [GOC:elh] +comment: Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome. +subset: goslim_pir +is_a: GO:0032993 ! protein-DNA complex +relationship: part_of GO:0140445 ! chromosome, telomeric repeat region + +[Term] +id: GO:0000783 +name: nuclear telomere cap complex +namespace: cellular_component +def: "A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome." [GOC:elh] +comment: Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome. +is_a: GO:0000782 ! telomere cap complex +intersection_of: GO:0000782 ! telomere cap complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000784 +name: nuclear chromosome, telomeric region +namespace: cellular_component +def: "The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres)." [GOC:elh] +comment: Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. +synonym: "nuclear chromosome, telomere" EXACT [] +is_a: GO:0000781 ! chromosome, telomeric region +intersection_of: GO:0000781 ! chromosome, telomeric region +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0000785 +name: chromatin +namespace: cellular_component +alt_id: GO:0005717 +def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130] +comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. +synonym: "chromosome scaffold" RELATED [] +xref: NIF_Subcellular:sao1615953555 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0000786 +name: nucleosome +namespace: cellular_component +alt_id: GO:0005718 +def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures." [GOC:elh] +subset: goslim_pir +xref: Wikipedia:Nucleosome +is_a: GO:0032993 ! protein-DNA complex +is_a: GO:0044815 ! DNA packaging complex +relationship: part_of GO:0000785 ! chromatin + +[Term] +id: GO:0000787 +name: cytoplasmic nucleosome +namespace: cellular_component +def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the cytoplasm into higher order structures." [GOC:elh] +is_a: GO:0000786 ! nucleosome +intersection_of: GO:0000786 ! nucleosome +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0000789 ! cytoplasmic chromatin + +[Term] +id: GO:0000788 +name: nuclear nucleosome +namespace: cellular_component +def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures." [GOC:elh] +is_a: GO:0000786 ! nucleosome +intersection_of: GO:0000786 ! nucleosome +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0000789 +name: cytoplasmic chromatin +namespace: cellular_component +def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm." [GOC:elh, PMID:20404130] +is_a: GO:0000785 ! chromatin +intersection_of: GO:0000785 ! chromatin +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0000229 ! cytoplasmic chromosome + +[Term] +id: GO:0000790 +name: nuclear chromatin +namespace: cellular_component +def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus." [GOC:elh, PMID:20404130] +is_a: GO:0000785 ! chromatin +intersection_of: GO:0000785 ! chromatin +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0000791 +name: euchromatin +namespace: cellular_component +def: "A dispersed and relatively uncompacted form of chromatin." [GOC:elh] +xref: NIF_Subcellular:sao445485807 +xref: Wikipedia:Euchromatin +is_a: GO:0000785 ! chromatin + +[Term] +id: GO:0000792 +name: heterochromatin +namespace: cellular_component +def: "A compact and highly condensed form of chromatin." [GOC:elh] +xref: NIF_Subcellular:sao581845896 +xref: Wikipedia:Heterochromatin +is_a: GO:0000785 ! chromatin + +[Term] +id: GO:0000793 +name: condensed chromosome +namespace: cellular_component +def: "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure." [GOC:elh] +comment: Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis. +synonym: "cytoplasmic mitotic chromosome" RELATED [] +synonym: "metaphase chromosome" RELATED [] +synonym: "mitotic chromosome" RELATED [] +is_a: GO:0005694 ! chromosome + +[Term] +id: GO:0000794 +name: condensed nuclear chromosome +namespace: cellular_component +def: "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome." [GOC:elh] +comment: Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome. +synonym: "meiotic chromosome" RELATED [] +synonym: "nuclear mitotic chromosome" RELATED [] +is_a: GO:0000228 ! nuclear chromosome +is_a: GO:0000793 ! condensed chromosome +intersection_of: GO:0000793 ! condensed chromosome +intersection_of: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000795 +name: synaptonemal complex +namespace: cellular_component +alt_id: GO:0005716 +def: "A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element." [DOI:10.5772/29752, GOC:elh] +xref: Wikipedia:Synaptonemal_complex +is_a: GO:0099086 ! synaptonemal structure +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0000796 +name: condensin complex +namespace: cellular_component +alt_id: GO:0005676 +alt_id: GO:0008620 +def: "A multisubunit protein complex that plays a central role in chromosome condensation." [GOC:elh] +subset: goslim_pir +synonym: "13S condensin complex" NARROW [] +synonym: "SMC complex" RELATED [] +is_a: GO:0044815 ! DNA packaging complex +relationship: part_of GO:0000793 ! condensed chromosome + +[Term] +id: GO:0000797 +name: condensin core heterodimer +namespace: cellular_component +alt_id: GO:0008621 +def: "The core heterodimer of a condensin complex, a multisubunit protein complex that plays a central role in chromosome condensation." [GOC:elh] +synonym: "8S condensin complex" NARROW [] +synonym: "Smc2-Smc4 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000796 ! condensin complex + +[Term] +id: GO:0000798 +name: nuclear cohesin complex +namespace: cellular_component +def: "A cohesin complex required for cohesion between sister chromatids that remain in the nucleus." [GOC:elh] +comment: Note that this term and its children should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i.e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used. +is_a: GO:0008278 ! cohesin complex +intersection_of: GO:0008278 ! cohesin complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0000799 +name: nuclear condensin complex +namespace: cellular_component +def: "A multisubunit protein complex that plays a central role in the condensation of chromosomes that remain in the nucleus." [GOC:elh] +is_a: GO:0000796 ! condensin complex +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0000800 +name: lateral element +namespace: cellular_component +def: "A proteinaceous core found between sister chromatids during meiotic prophase." [GOC:elh] +comment: In species that have a synaptonemal complex, the lateral elements are part of this complex. S.pombe is an example of a species that lacks a (canonical) synaptonemal complex, but still has lateral elements. +synonym: "axial element" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000795 ! synaptonemal complex + +[Term] +id: GO:0000801 +name: central element +namespace: cellular_component +def: "A structural unit of the synaptonemal complex found between the lateral elements." [GOC:elh] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000795 ! synaptonemal complex + +[Term] +id: GO:0000802 +name: transverse filament +namespace: cellular_component +def: "A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them." [GOC:elh] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000795 ! synaptonemal complex + +[Term] +id: GO:0000803 +name: sex chromosome +namespace: cellular_component +def: "A chromosome involved in sex determination." [GOC:elh] +is_a: GO:0005694 ! chromosome + +[Term] +id: GO:0000804 +name: W chromosome +namespace: cellular_component +def: "The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females." [GOC:mah, GOC:mr, ISBN:0321000382, PMID:20622855] +xref: Wikipedia:ZW_sex-determination_system +is_a: GO:0000803 ! sex chromosome +property_value: RO:0002161 NCBITaxon:40674 + +[Term] +id: GO:0000805 +name: X chromosome +namespace: cellular_component +def: "The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males." [GOC:mah, GOC:mr, ISBN:0582227089, PMID:20622855, Wikipedia:XY_sex-determination_system] +xref: Wikipedia:X_chromosome +is_a: GO:0000803 ! sex chromosome +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0000806 +name: Y chromosome +namespace: cellular_component +def: "The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males." [GOC:mah, GOC:mr, ISBN:0582227089, PMID:20622855, Wikipedia:XY_sex-determination_system] +xref: Wikipedia:Y_chromosome +is_a: GO:0000803 ! sex chromosome +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0000807 +name: Z chromosome +namespace: cellular_component +def: "The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females." [GOC:mah, GOC:mr, ISBN:0321000382, PMID:20622855] +xref: Wikipedia:ZW_sex-determination_system +is_a: GO:0000803 ! sex chromosome +property_value: RO:0002161 NCBITaxon:40674 + +[Term] +id: GO:0000808 +name: origin recognition complex +namespace: cellular_component +def: "A multisubunit complex that is located at the replication origins of a chromosome." [GOC:elh] +subset: goslim_pir +synonym: "ORC" EXACT [] +synonym: "origin of replication recognition complex" EXACT [] +xref: Wikipedia:Origin_recognition_complex +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0000809 +name: cytoplasmic origin of replication recognition complex +namespace: cellular_component +def: "A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm." [GOC:elh] +synonym: "cytoplasmic ORC" EXACT [] +synonym: "prokaryotic ORC" RELATED [] +is_a: GO:0000808 ! origin recognition complex +intersection_of: GO:0000808 ! origin recognition complex +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0000229 ! cytoplasmic chromosome + +[Term] +id: GO:0000810 +name: diacylglycerol diphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate." [GOC:kad, PMID:8567632, PMID:9452443] +synonym: "DGPP phosphatase activity" EXACT [] +synonym: "DGPP phosphohydrolase activity" EXACT [] +synonym: "diacylglycerol pyrophosphate phosphatase activity" EXACT [] +xref: EC:3.1.3.81 +xref: MetaCyc:RXN-11277 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0000811 +name: GINS complex +namespace: cellular_component +def: "A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks." [GOC:rb, GOC:rn, PMID:12730134, PMID:16990792, PMID:17467990] +synonym: "Go, Ichi, Ni and San complex" EXACT [] +is_a: GO:0031261 ! DNA replication preinitiation complex +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0000812 +name: Swr1 complex +namespace: cellular_component +def: "A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits." [GOC:rb, PMID:14645854, PMID:14690608, PMID:19355820] +synonym: "SWR-C" EXACT [] +is_a: GO:0000118 ! histone deacetylase complex +is_a: GO:0097346 ! INO80-type complex + +[Term] +id: GO:0000813 +name: ESCRT I complex +namespace: cellular_component +def: "An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes." [GOC:rb, PMID:12892785, PMID:12900393] +synonym: "endosomal sorting complex required for transport" BROAD [] +is_a: GO:0036452 ! ESCRT complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0000814 +name: ESCRT II complex +namespace: cellular_component +def: "An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes." [GOC:rb, PMID:12892785, PMID:12900393] +synonym: "endosomal sorting complex required for transport" BROAD [] +is_a: GO:0036452 ! ESCRT complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0000815 +name: ESCRT III complex +namespace: cellular_component +def: "An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes." [GOC:rb, PMID:12892785, PMID:12900393] +synonym: "endosomal sorting complex required for transport" BROAD [] +is_a: GO:0036452 ! ESCRT complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0000817 +name: COMA complex +namespace: cellular_component +def: "A multiprotein complex in yeast consisting of Ctf19p, Okp1p, Mcm21p, and Ame1p. This complex bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly." [GOC:se, PMID:14633972] +synonym: "Ctf19p-Okp1p-Mcm1p-Ame1p complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000778 ! condensed nuclear chromosome kinetochore + +[Term] +id: GO:0000818 +name: nuclear MIS12/MIND complex +namespace: cellular_component +def: "A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1." [GOC:krc, GOC:se, PMID:14633972] +synonym: "MIND complex" EXACT [] +synonym: "Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex" EXACT [] +is_a: GO:0000444 ! MIS12/MIND type complex +intersection_of: GO:0000444 ! MIS12/MIND type complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0000778 ! condensed nuclear chromosome kinetochore + +[Term] +id: GO:0000819 +name: sister chromatid segregation +namespace: biological_process +def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] +is_a: GO:0051276 ! chromosome organization +is_a: GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0000820 +name: regulation of glutamine family amino acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:go_curators] +synonym: "regulation of glutamine family amino acid metabolism" EXACT [] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009064 ! glutamine family amino acid metabolic process +relationship: regulates GO:0009064 ! glutamine family amino acid metabolic process + +[Term] +id: GO:0000821 +name: regulation of arginine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid." [GOC:go_curators] +synonym: "regulation of arginine metabolism" EXACT [] +is_a: GO:0000820 ! regulation of glutamine family amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006525 ! arginine metabolic process +relationship: regulates GO:0006525 ! arginine metabolic process + +[Term] +id: GO:0000822 +name: inositol hexakisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with inositol hexakisphosphate." [GOC:go_curators] +synonym: "InsP6 binding" EXACT [] +synonym: "IP6 binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0000823 +name: inositol-1,4,5-trisphosphate 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+)." [MetaCyc:2.7.1.151-RXN] +synonym: "ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity" EXACT [] +synonym: "inositol polyphosphate multikinase activity" BROAD [] +synonym: "inositol trisphosphate 6-kinase activity" BROAD [] +synonym: "IpmK" BROAD [] +xref: EC:2.7.1.151 +xref: KEGG_REACTION:R05800 +xref: MetaCyc:2.7.1.151-RXN +is_a: GO:0051766 ! inositol trisphosphate kinase activity + +[Term] +id: GO:0000824 +name: inositol tetrakisphosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate." [GOC:elh] +synonym: "1D-myo-inositol-tetrakisphosphate 3-kinase activity" EXACT [] +synonym: "EC:2.7.1.151" BROAD [] +synonym: "inositol 1,4,5,6-tetrakisphosphate 3-kinase activity" EXACT [] +synonym: "inositol polyphosphate multikinase activity" BROAD [] +synonym: "IpmK" BROAD [] +xref: Reactome:R-HSA-1855185 "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus" +is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity + +[Term] +id: GO:0000825 +name: inositol tetrakisphosphate 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [GOC:elh] +synonym: "1D-myo-inositol-tetrakisphosphate 6-kinase activity" EXACT [] +synonym: "inositol 1,3,4,5-tetrakisphosphate 6-kinase activity" EXACT [] +xref: MetaCyc:RXN-7184 +xref: Reactome:R-HSA-1855206 "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus" +is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity + +[Term] +id: GO:0000826 +name: obsolete inositol pyrophosphate synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds." [GOC:elh, PMID:16429326] +comment: This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them. +synonym: "inositol diphosphate synthase activity" EXACT [] +synonym: "inositol pyrophosphate synthase activity" EXACT [] +is_obsolete: true +consider: GO:0052746 + +[Term] +id: GO:0000827 +name: inositol-1,3,4,5,6-pentakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown." [GOC:elh, PMID:11311242] +synonym: "EC:2.7.4.21" BROAD [] +xref: Reactome:R-HSA-1855181 "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus" +xref: Reactome:R-HSA-1855223 "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0000828 +name: inositol hexakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown." [GOC:elh, GOC:vw, PMID:16429326] +xref: Reactome:R-HSA-1855207 "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus" +xref: Reactome:R-HSA-1855216 "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol" +xref: Reactome:R-HSA-1855227 "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0000829 +name: inositol heptakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown." [GOC:elh, PMID:16429326] +xref: Reactome:R-HSA-1855157 "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus" +xref: Reactome:R-HSA-1855182 "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol" +xref: Reactome:R-HSA-1855194 "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0000830 +name: inositol hexakisphosphate 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate." [GOC:elh, PMID:16429326] +is_a: GO:0000828 ! inositol hexakisphosphate kinase activity + +[Term] +id: GO:0000831 +name: inositol hexakisphosphate 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate." [GOC:elh, PMID:16429326] +is_a: GO:0000828 ! inositol hexakisphosphate kinase activity + +[Term] +id: GO:0000832 +name: inositol hexakisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate." [MetaCyc:2.7.1.152-RXN] +synonym: "ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity" EXACT [] +xref: EC:2.7.4.21 +xref: KEGG_REACTION:R09087 +xref: MetaCyc:2.7.1.152-RXN +is_a: GO:0000828 ! inositol hexakisphosphate kinase activity + +[Term] +id: GO:0000833 +name: inositol heptakisphosphate 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate." [GOC:elh, PMID:16429326] +synonym: "diphosphoinositol-pentakisphosphate 4-kinase activity" EXACT [] +synonym: "IP7 4-kinase activity" EXACT [] +is_a: GO:0000829 ! inositol heptakisphosphate kinase activity + +[Term] +id: GO:0000834 +name: inositol heptakisphosphate 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [GOC:elh, PMID:16429326] +is_a: GO:0000829 ! inositol heptakisphosphate kinase activity + +[Term] +id: GO:0000835 +name: ER ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex found in the ER." [GOC:elh] +is_a: GO:0000153 ! cytoplasmic ubiquitin ligase complex +is_a: GO:0098796 ! membrane protein complex +intersection_of: GO:0000151 ! ubiquitin ligase complex +intersection_of: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0000836 +name: Hrd1p ubiquitin ligase complex +namespace: cellular_component +def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78)." [GOC:bf, GOC:elh, PMID:16619026, PMID:16873066, PMID:21454652] +synonym: "HRD1 ubiquitin ligase complex" RELATED [GOC:bf] +is_a: GO:0000835 ! ER ubiquitin ligase complex + +[Term] +id: GO:0000837 +name: Doa10p ubiquitin ligase complex +namespace: cellular_component +def: "A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p." [GOC:elh, PMID:16873066] +synonym: "Ssm4p ubiquitin ligase complex" EXACT [] +is_a: GO:0000835 ! ER ubiquitin ligase complex + +[Term] +id: GO:0000838 +name: Hrd1p ubiquitin ligase ERAD-M complex +namespace: cellular_component +def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p." [GOC:elh, PMID:16873066] +is_a: GO:0000836 ! Hrd1p ubiquitin ligase complex + +[Term] +id: GO:0000839 +name: Hrd1p ubiquitin ligase ERAD-L complex +namespace: cellular_component +def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p." [GOC:elh, PMID:16873065, PMID:16873066] +is_a: GO:0000836 ! Hrd1p ubiquitin ligase complex + +[Term] +id: GO:0000900 +name: translation repressor activity, mRNA regulatory element binding +namespace: molecular_function +def: "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid." [GOC:clt, GOC:vw, PMID:29061112, PMID:7523370] +synonym: "translation repressor activity, nucleic acid binding" BROAD [] +is_a: GO:0030371 ! translation repressor activity +is_a: GO:0090079 ! translation regulator activity, nucleic acid binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15049 xsd:anyURI + +[Term] +id: GO:0000901 +name: translation repressor activity, non-nucleic acid binding +namespace: molecular_function +def: "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid." [GOC:clt] +is_a: GO:0030371 ! translation repressor activity +is_a: GO:0045183 ! translation factor activity, non-nucleic acid binding + +[Term] +id: GO:0000902 +name: cell morphogenesis +namespace: biological_process +alt_id: GO:0007148 +alt_id: GO:0045790 +alt_id: GO:0045791 +def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "cellular morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0000903 +name: obsolete regulation of cell shape during vegetative growth phase +namespace: biological_process +alt_id: GO:0090061 +def: "OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods." [GOC:clt, GOC:go_curators, GOC:vw] +comment: The reason for obsoletion is that biological phases should be captured as extensions. +synonym: "cell morphogenesis during vegetative growth phase" RELATED [GOC:vw] +synonym: "cellular morphogenesis during vegetative growth" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of cell morphogenesis during vegetative growth phase" RELATED [] +is_obsolete: true + +[Term] +id: GO:0000904 +name: cell morphogenesis involved in differentiation +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:go_curators] +is_a: GO:0000902 ! cell morphogenesis +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0048468 ! cell development +relationship: part_of GO:0048468 ! cell development + +[Term] +id: GO:0000905 +name: sporocarp development involved in asexual reproduction +namespace: biological_process +def: "The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction." [GOC:clt, GOC:mtg_sensu] +synonym: "conidium development" NARROW [] +synonym: "fruiting body formation involved in asexual reproduction" BROAD [] +synonym: "haploid fruiting" RELATED [] +synonym: "homokaryotic fruiting" RELATED [] +synonym: "imperfect stage fruiting body development" NARROW [] +synonym: "monokaryotic fruiting" RELATED [] +is_a: GO:0030584 ! sporocarp development +intersection_of: GO:0030584 ! sporocarp development +intersection_of: part_of GO:0019954 ! asexual reproduction +relationship: part_of GO:0019954 ! asexual reproduction + +[Term] +id: GO:0000906 +name: 6,7-dimethyl-8-ribityllumazine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate." [PMID:7559556] +synonym: "lumazine synthase activity" BROAD [MetaCyc:LUMAZINESYN-CPLX] +xref: EC:2.5.1.78 +xref: MetaCyc:LUMAZINESYN-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0000907 +name: sulfonate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2." [GOC:clt, PMID:10482536] +synonym: "sulfonate/alpha-ketoglutarate dioxygenase activity" EXACT [] +synonym: "sulphonate dioxygenase activity" EXACT [] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0000908 +name: taurine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite." [EC:1.14.11.17, RHEA:15909] +synonym: "2-aminoethanesulfonate dioxygenase activity" EXACT [EC:1.14.11.17] +synonym: "alpha-ketoglutarate-dependent taurine dioxygenase activity" EXACT [EC:1.14.11.17] +synonym: "taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)" EXACT [EC:1.14.11.17] +xref: EC:1.14.11.17 +xref: KEGG_REACTION:R05320 +xref: MetaCyc:RXN0-299 +xref: RHEA:15909 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0000909 +name: sporocarp development involved in sexual reproduction +namespace: biological_process +def: "The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi." [GOC:clt, GOC:mtg_sensu] +synonym: "ascus development" NARROW [] +synonym: "fruiting body development involved in sexual reproduction" BROAD [] +synonym: "fruiting body formation involved in sexual reproduction" BROAD [] +synonym: "perfect stage fruiting body development" NARROW [] +is_a: GO:0030584 ! sporocarp development +intersection_of: GO:0030584 ! sporocarp development +intersection_of: part_of GO:0019953 ! sexual reproduction +relationship: part_of GO:0019953 ! sexual reproduction + +[Term] +id: GO:0000910 +name: cytokinesis +namespace: biological_process +alt_id: GO:0007104 +alt_id: GO:0016288 +alt_id: GO:0033205 +def: "The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other. +subset: gocheck_do_not_manually_annotate +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_yeast +synonym: "cell cycle cytokinesis" EXACT [] +synonym: "cytokinesis involved in cell cycle" EXACT [GOC:dph, GOC:tb] +xref: Wikipedia:Cytokinesis +is_a: GO:0022402 ! cell cycle process +relationship: has_part GO:0090148 ! membrane fission +relationship: part_of GO:0051301 ! cell division + +[Term] +id: GO:0000911 +name: cytokinesis by cell plate formation +namespace: biological_process +def: "The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana." [GOC:clt] +is_a: GO:0000910 ! cytokinesis + +[Term] +id: GO:0000912 +name: assembly of actomyosin apparatus involved in cytokinesis +namespace: biological_process +def: "The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis." [GOC:mtg_cell_cycle] +synonym: "actomyosin apparatus assembly involved in cytokinesis" EXACT [GOC:mah] +synonym: "cytokinesis, formation of actomyosin apparatus" EXACT [GOC:dph, GOC:tb] +synonym: "formation of actomyosin apparatus involved in cytokinesis" RELATED [GOC:dph] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0032506 ! cytokinetic process +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis + +[Term] +id: GO:0000913 +name: preprophase band assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation." [GOC:clt, GOC:mah] +synonym: "preprophase band formation" RELATED [GOC:mah] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0000911 ! cytokinesis by cell plate formation + +[Term] +id: GO:0000914 +name: phragmoplast assembly +namespace: biological_process +def: "The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles)." [GOC:clt] +synonym: "phragmoplast formation" RELATED [goc:dph] +is_a: GO:1902407 ! assembly of actomyosin apparatus involved in mitotic cytokinesis +relationship: part_of GO:0000911 ! cytokinesis by cell plate formation + +[Term] +id: GO:0000915 +name: actomyosin contractile ring assembly +namespace: biological_process +alt_id: GO:0045573 +def: "The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis." [GOC:clt, GOC:dph, GOC:tb] +synonym: "constriction ring assembly" NARROW [] +synonym: "contractile ring assembly" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "cytokinesis, actomyosin contractile ring assembly" EXACT [] +synonym: "cytokinesis, actomyosin contractile ring formation" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "cytokinesis, actomyosin ring biosynthesis" RELATED [] +synonym: "cytokinesis, actomyosin ring formation" RELATED [] +synonym: "cytokinesis, contractile ring assembly" RELATED [GOC:mah] +is_a: GO:0000912 ! assembly of actomyosin apparatus involved in cytokinesis +is_a: GO:0044837 ! actomyosin contractile ring organization + +[Term] +id: GO:0000916 +name: actomyosin contractile ring contraction +namespace: biological_process +def: "The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle." [GOC:clt, GOC:dph, GOC:mah, GOC:tb] +synonym: "contractile ring constriction" BROAD [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "contractile ring contraction involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "cytokinesis, actomyosin ring contraction" EXACT [] +synonym: "cytokinesis, contractile ring contraction" BROAD [GOC:dph, GOC:tb] +is_a: GO:0036213 ! contractile ring contraction +relationship: part_of GO:0044837 ! actomyosin contractile ring organization + +[Term] +id: GO:0000917 +name: division septum assembly +namespace: biological_process +alt_id: GO:0071937 +alt_id: GO:1902411 +def: "The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material." [GOC:mtg_cell_cycle] +synonym: "division septum assembly involved in cell cycle cytokinesis" NARROW [] +synonym: "division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "division septum formation" EXACT [GOC:mah] +synonym: "division septum formation involved in cell cycle cytokinesis" NARROW [] +synonym: "division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "division septum formation involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "formation of division septum" EXACT [] +synonym: "formation of division septum involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "mitotic division septum assembly" NARROW [] +synonym: "septation" BROAD [] +synonym: "septin assembly and septum biosynthesis" RELATED [] +synonym: "septin assembly and septum biosynthesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "septin assembly and septum formation" RELATED [] +synonym: "septin assembly and septum formation involved in mitotic cell cycle" NARROW [GOC:TermGenie] +is_a: GO:0090529 ! cell septum assembly + +[Term] +id: GO:0000918 +name: division septum site selection +namespace: biological_process +def: "The process of marking the site where a division septum will form." [GOC:clt] +synonym: "selection of site for barrier cell septum biosynthesis" EXACT [] +synonym: "selection of site for barrier cell septum formation" EXACT [] +synonym: "selection of site for division septum formation" EXACT [] +synonym: "septin assembly and septum biosynthesis" BROAD [] +synonym: "septin assembly and septum formation" BROAD [] +synonym: "septum positioning" EXACT [] +is_a: GO:0032506 ! cytokinetic process +relationship: part_of GO:0000917 ! division septum assembly +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0000919 +name: cell plate assembly +namespace: biological_process +def: "The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast." [GOC:clt] +synonym: "cell plate formation" RELATED [GOC:mah] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0000911 ! cytokinesis by cell plate formation + +[Term] +id: GO:0000920 +name: septum digestion after cytokinesis +namespace: biological_process +alt_id: GO:1902409 +alt_id: GO:2000695 +def: "The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis." [GOC:mtg_cell_cycle, GOC:vw] +comment: This term should not be used to describe the last step of cytokinesis in organisms without a cell wall, ie, the cell resealing of the plasma membrane via abscission. Consider annotating to 'GO:0061952 midbody abscission' to capture this process. +synonym: "cell separation after cytokinesis" RELATED [] +synonym: "cell separation following cytokinesis" EXACT [GOC:dph, GOC:tb] +synonym: "cytokinetic cell separation" RELATED [] +synonym: "daughter cell separation" RELATED [] +synonym: "mitotic cytokinetic cell separation" BROAD [] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0051301 ! cell division +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0000921 +name: septin ring assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex." [GOC:clt] +synonym: "septin assembly and septum biosynthesis" BROAD [] +synonym: "septin assembly and septum formation" BROAD [] +is_a: GO:0031106 ! septin ring organization +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0070925 ! organelle assembly + +[Term] +id: GO:0000922 +name: spindle pole +namespace: cellular_component +alt_id: GO:0030615 +def: "Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules." [GOC:clt] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005819 ! spindle + +[Term] +id: GO:0000923 +name: equatorial microtubule organizing center +namespace: cellular_component +def: "A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis." [PMID:11792817] +synonym: "EMTOC" EXACT [] +synonym: "equatorial microtubule organising centre" EXACT [] +is_a: GO:0005815 ! microtubule organizing center +intersection_of: GO:0005815 ! microtubule organizing center +intersection_of: part_of GO:0032153 ! cell division site +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0000924 +name: gamma-tubulin ring complex, centrosomal +namespace: cellular_component +alt_id: GO:0000925 +alt_id: GO:0000926 +def: "A centrosome-localized multiprotein complex composed of gamma-tubulin and other non-tubulin proteins assembled into a ring structure that is thought to be the unit of nucleation at the minus end of a microtubule. Gamma-tubulin small complexes are thought to be the core repeating units of the ring." [GOC:clt, GOC:mtg_sensu, PMID:12134075, PMID:17021256] +synonym: "gamma-tubulin large complex, centrosomal" EXACT [] +is_a: GO:0008274 ! gamma-tubulin ring complex +intersection_of: GO:0008274 ! gamma-tubulin ring complex +intersection_of: part_of GO:0000242 ! pericentriolar material +relationship: part_of GO:0000242 ! pericentriolar material + +[Term] +id: GO:0000927 +name: gamma-tubulin small complex, centrosomal +namespace: cellular_component +def: "A centrosomal complex usually comprising two gamma-tubulin molecules, at least two conserved non-tubulin proteins that multimerize along with additional non-tubulin proteins in animal cells into larger functional complexes. Gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex. An example of this structure is found in Mus musculus." [GOC:mtg_sensu, PMID:12134075] +is_a: GO:0008275 ! gamma-tubulin small complex + +[Term] +id: GO:0000928 +name: gamma-tubulin small complex, spindle pole body +namespace: cellular_component +def: "A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae." [GOC:mtg_sensu, PMID:12134075] +synonym: "Tub4 complex" EXACT [] +is_a: GO:0008275 ! gamma-tubulin small complex +intersection_of: GO:0008275 ! gamma-tubulin small complex +intersection_of: part_of GO:0005816 ! spindle pole body +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0000930 +name: gamma-tubulin complex +namespace: cellular_component +def: "A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species." [GOC:clt, PMID:12134075] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005815 ! microtubule organizing center + +[Term] +id: GO:0000931 +name: gamma-tubulin large complex +namespace: cellular_component +alt_id: GO:0000929 +def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe." [GOC:mtg_sensu, PMID:12134075] +is_a: GO:0000930 ! gamma-tubulin complex + +[Term] +id: GO:0000932 +name: P-body +namespace: cellular_component +def: "A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing." [GOC:clt, PMID:12730603] +synonym: "cytoplasmic foci" RELATED [] +synonym: "cytoplasmic mRNA processing body" EXACT [] +synonym: "P body" EXACT [] +xref: Wikipedia:P_body +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule + +[Term] +id: GO:0000933 +name: adventitious septum +namespace: cellular_component +def: "A cell septum whose formation is independent of nuclear division." [GOC:clt, ISBN:0471940526] +is_a: GO:0030428 ! cell septum + +[Term] +id: GO:0000934 +name: porous cell septum +namespace: cellular_component +def: "A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments." [GOC:clt] +synonym: "porous septum" BROAD [] +is_a: GO:0030428 ! cell septum + +[Term] +id: GO:0000935 +name: division septum +namespace: cellular_component +def: "A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments." [GOC:clt, GOC:vw] +synonym: "complete septum" EXACT [] +synonym: "divison septum" EXACT [] +is_a: GO:0030428 ! cell septum +intersection_of: GO:0030428 ! cell septum +intersection_of: part_of GO:0032153 ! cell division site +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0000936 +name: primary cell septum +namespace: cellular_component +def: "A cell septum that forms following nuclear division." [GOC:clt, ISBN:0471940526] +synonym: "primary septum" BROAD [] +is_a: GO:0000935 ! division septum + +[Term] +id: GO:0000937 +name: dolipore septum +namespace: cellular_component +def: "A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome)." [GOC:clt] +is_a: GO:0000934 ! porous cell septum + +[Term] +id: GO:0000938 +name: GARP complex +namespace: cellular_component +def: "A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles." [GOC:clt, GOC:rn, PMID:10637310, PMID:12077354, PMID:12446664] +synonym: "Golgi associated retrograde protein complex" EXACT [] +synonym: "VFT tethering complex" EXACT [] +synonym: "Vps fifty three tethering complex" EXACT [] +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0000939 +name: condensed chromosome inner kinetochore +namespace: cellular_component +def: "The region of a condensed chromosome kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome." [GOC:clt, PMID:10619130, PMID:11483983] +synonym: "inner centromere core complex" RELATED [] +synonym: "inner kinetochore of condensed chromosome" EXACT [] +synonym: "inner kinetochore plate" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000777 ! condensed chromosome kinetochore + +[Term] +id: GO:0000940 +name: condensed chromosome outer kinetochore +namespace: cellular_component +def: "The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions." [GOC:clt, PMID:11483983] +synonym: "outer kinetochore of condensed chromosome" EXACT [] +synonym: "outer kinetochore plate" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000777 ! condensed chromosome kinetochore + +[Term] +id: GO:0000941 +name: condensed nuclear chromosome inner kinetochore +namespace: cellular_component +def: "The region of a condensed nuclear chromosome kinetochore closest to centromeric DNA; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome." [GOC:clt, PMID:10619130, PMID:1148398] +synonym: "inner kinetochore of condensed nuclear chromosome" EXACT [] +is_a: GO:0000939 ! condensed chromosome inner kinetochore +intersection_of: GO:0000939 ! condensed chromosome inner kinetochore +intersection_of: part_of GO:0000778 ! condensed nuclear chromosome kinetochore +relationship: part_of GO:0000778 ! condensed nuclear chromosome kinetochore + +[Term] +id: GO:0000942 +name: condensed nuclear chromosome outer kinetochore +namespace: cellular_component +def: "The region of a condensed nuclear chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions." [GOC:clt, PMID:1148398] +synonym: "outer kinetochore of condensed nuclear chromosome" EXACT [] +is_a: GO:0000940 ! condensed chromosome outer kinetochore +intersection_of: GO:0000940 ! condensed chromosome outer kinetochore +intersection_of: part_of GO:0000778 ! condensed nuclear chromosome kinetochore +relationship: part_of GO:0000778 ! condensed nuclear chromosome kinetochore + +[Term] +id: GO:0000943 +name: retrotransposon nucleocapsid +namespace: cellular_component +def: "A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog." [GOC:clt, PMID:10861903] +synonym: "Virus-like particle" EXACT [] +synonym: "VLP" EXACT [] +xref: Wikipedia:Virus-like_particle +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0000947 +name: amino acid catabolic process to alcohol via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols." [GOC:krc, PMID:18281432] +is_a: GO:0000955 ! amino acid catabolic process via Ehrlich pathway +is_a: GO:0046165 ! alcohol biosynthetic process + +[Term] +id: GO:0000948 +name: amino acid catabolic process to carboxylic acid via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids." [GOC:krc, PMID:18281432] +is_a: GO:0000955 ! amino acid catabolic process via Ehrlich pathway +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0000949 +name: aromatic amino acid family catabolic process to alcohol via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols." [GOC:krc, PMID:18281432] +is_a: GO:0000947 ! amino acid catabolic process to alcohol via Ehrlich pathway +is_a: GO:0009074 ! aromatic amino acid family catabolic process + +[Term] +id: GO:0000950 +name: branched-chain amino acid catabolic process to alcohol via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols." [GOC:krc, PMID:18281432] +synonym: "branched chain family amino acid catabolic process to alcohol via Ehrlich pathway" EXACT [GOC:krc] +is_a: GO:0000947 ! amino acid catabolic process to alcohol via Ehrlich pathway +is_a: GO:0009083 ! branched-chain amino acid catabolic process + +[Term] +id: GO:0000951 +name: methionine catabolic process to 3-methylthiopropanol +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols." [GOC:krc, PMID:18281432] +is_a: GO:0000947 ! amino acid catabolic process to alcohol via Ehrlich pathway +is_a: GO:0009087 ! methionine catabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0000952 +name: aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids." [GOC:krc, PMID:18281432] +is_a: GO:0000948 ! amino acid catabolic process to carboxylic acid via Ehrlich pathway +is_a: GO:0009074 ! aromatic amino acid family catabolic process + +[Term] +id: GO:0000953 +name: branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids." [GOC:krc, PMID:18281432] +synonym: "branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway" EXACT [GOC:krc] +is_a: GO:0000948 ! amino acid catabolic process to carboxylic acid via Ehrlich pathway +is_a: GO:0009083 ! branched-chain amino acid catabolic process + +[Term] +id: GO:0000954 +name: methionine catabolic process to 3-methylthiopropanoate +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids." [GOC:krc, PMID:18281432] +is_a: GO:0000948 ! amino acid catabolic process to carboxylic acid via Ehrlich pathway +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0009087 ! methionine catabolic process +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0000955 +name: amino acid catabolic process via Ehrlich pathway +namespace: biological_process +def: "The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols." [GOC:krc, PMID:18281432] +is_a: GO:0009063 ! cellular amino acid catabolic process + +[Term] +id: GO:0000956 +name: nuclear-transcribed mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells." [GOC:krc] +synonym: "nuclear mRNA breakdown" EXACT [] +synonym: "nuclear mRNA catabolism" EXACT [] +synonym: "nuclear mRNA degradation" EXACT [] +is_a: GO:0006402 ! mRNA catabolic process + +[Term] +id: GO:0000957 +name: mitochondrial RNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." [GOC:krc, GOC:mah] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006401 ! RNA catabolic process +intersection_of: GO:0006401 ! RNA catabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000958 +name: mitochondrial mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion." [GOC:krc, GOC:mah] +is_a: GO:0000957 ! mitochondrial RNA catabolic process +is_a: GO:0006402 ! mRNA catabolic process +intersection_of: GO:0006402 ! mRNA catabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000959 +name: mitochondrial RNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." [GOC:krc, GOC:mah] +is_a: GO:0016070 ! RNA metabolic process +intersection_of: GO:0016070 ! RNA metabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000960 +name: regulation of mitochondrial RNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000957 ! mitochondrial RNA catabolic process +relationship: regulates GO:0000957 ! mitochondrial RNA catabolic process + +[Term] +id: GO:0000961 +name: negative regulation of mitochondrial RNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] +is_a: GO:0000960 ! regulation of mitochondrial RNA catabolic process +is_a: GO:1902369 ! negative regulation of RNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000957 ! mitochondrial RNA catabolic process +relationship: negatively_regulates GO:0000957 ! mitochondrial RNA catabolic process + +[Term] +id: GO:0000962 +name: positive regulation of mitochondrial RNA catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] +is_a: GO:0000960 ! regulation of mitochondrial RNA catabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0051254 ! positive regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000957 ! mitochondrial RNA catabolic process +relationship: positively_regulates GO:0000957 ! mitochondrial RNA catabolic process + +[Term] +id: GO:0000963 +name: mitochondrial RNA processing +namespace: biological_process +def: "The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion." [GOC:krc, GOC:mah] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006396 ! RNA processing +is_a: GO:0140053 ! mitochondrial gene expression +intersection_of: GO:0006396 ! RNA processing +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000964 +name: mitochondrial RNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion." [GOC:krc, GOC:mah] +synonym: "mitochondrial RNA 5' end processing" RELATED [] +is_a: GO:0000963 ! mitochondrial RNA processing +is_a: GO:0000966 ! RNA 5'-end processing +intersection_of: GO:0000966 ! RNA 5'-end processing +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000965 +name: mitochondrial RNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion." [GOC:krc, GOC:mah] +synonym: "mitochondrial RNA 3' end processing" RELATED [] +is_a: GO:0000963 ! mitochondrial RNA processing +is_a: GO:0031123 ! RNA 3'-end processing +intersection_of: GO:0031123 ! RNA 3'-end processing +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0000966 +name: RNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of an RNA molecule." [GOC:krc] +synonym: "RNA 5' end processing" EXACT [] +is_a: GO:0006396 ! RNA processing + +[Term] +id: GO:0000967 +name: rRNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of an rRNA molecule." [GOC:krc] +synonym: "rRNA 5' end processing" EXACT [] +is_a: GO:0006364 ! rRNA processing +is_a: GO:0034471 ! ncRNA 5'-end processing + +[Term] +id: GO:0000968 +name: tRNA exon ligation +namespace: biological_process +def: "An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed." [GOC:krc] +is_a: GO:0000378 ! RNA exon ligation +relationship: part_of GO:0006388 ! tRNA splicing, via endonucleolytic cleavage and ligation +created_by: krc +creation_date: 2009-04-28T10:22:40Z + +[Term] +id: GO:0000969 +name: tRNA exon ligation utilizing ATP as source of linkage phosphate +namespace: biological_process +def: "A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species." [GOC:krc, PMID:17786051] +is_a: GO:0000968 ! tRNA exon ligation +created_by: krc +creation_date: 2009-04-28T10:29:37Z + +[Term] +id: GO:0000970 +name: tRNA exon ligation utilizing GTP as source of linkage phosphate +namespace: biological_process +def: "A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process." [GOC:krc, PMID:18217203, PMID:9299409] +is_a: GO:0000968 ! tRNA exon ligation +created_by: krc +creation_date: 2009-04-28T10:33:25Z + +[Term] +id: GO:0000971 +name: tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate +namespace: biological_process +def: "A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans." [GOC:krc, PMID:17786051, PMID:18217203, PMID:9299409] +is_a: GO:0000968 ! tRNA exon ligation +created_by: krc +creation_date: 2009-04-28T10:36:17Z + +[Term] +id: GO:0000972 +name: transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery +namespace: biological_process +def: "The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript." [GOC:krc, PMID:18614049] +is_a: GO:0051276 ! chromosome organization +created_by: krc +creation_date: 2009-09-10T12:25:11Z + +[Term] +id: GO:0000973 +name: posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery +namespace: biological_process +def: "The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed." [GOC:krc, PMID:17373856, PMID:18614049] +is_a: GO:0000972 ! transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery +created_by: krc +creation_date: 2009-09-10T12:28:04Z + +[Term] +id: GO:0000974 +name: Prp19 complex +namespace: cellular_component +def: "A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p." [GOC:krc, PMID:16540691, PMID:19239890] +synonym: "nineteen complex" NARROW [] +synonym: "NTC" RELATED [] +synonym: "Prp19/CDC5 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2009-10-12T10:01:30Z + +[Term] +id: GO:0000976 +name: transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0000975 +alt_id: GO:0044212 +def: "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon." [GOC:txnOH] +comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. +synonym: "regulatory region DNA binding" BROAD [] +synonym: "transcription regulatory region DNA binding" RELATED [] +is_a: GO:0001067 ! regulatory region nucleic acid binding +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19312 xsd:anyURI +created_by: krc +creation_date: 2010-08-10T11:00:02Z + +[Term] +id: GO:0000977 +name: RNA polymerase II transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001012 +def: "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II." [GOC:txnOH] +comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. +synonym: "RNA polymerase II regulatory region DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19312 xsd:anyURI +created_by: krc +creation_date: 2010-08-10T11:05:36Z + +[Term] +id: GO:0000978 +name: RNA polymerase II cis-regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0000980 +def: "Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II." [GOC:txnOH-2018] +comment: Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer". +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase II distal enhancer sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase II promoter proximal region sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding" RELATED [] +is_a: GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +is_a: GO:0000987 ! cis-regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-10T02:17:19Z + +[Term] +id: GO:0000979 +name: RNA polymerase II core promoter sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene." [GOC:pg, GOC:txnOH, PMID:12381658] +is_a: GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +is_a: GO:0001046 ! core promoter sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-10T02:17:28Z + +[Term] +id: GO:0000981 +name: DNA-binding transcription factor activity, RNA polymerase II-specific +namespace: molecular_function +alt_id: GO:0000982 +alt_id: GO:0001133 +alt_id: GO:0001200 +alt_id: GO:0001201 +alt_id: GO:0001202 +alt_id: GO:0001203 +alt_id: GO:0003705 +def: "A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units." [GOC:txnOH-2018] +synonym: "copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW [] +synonym: "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW [] +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity" NARROW [] +synonym: "RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" NARROW [] +synonym: "RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, sequence-specific DNA binding" EXACT [] +synonym: "RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding" EXACT [] +synonym: "RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity" NARROW [] +synonym: "sequence-specific DNA binding RNA polymerase II transcription factor activity" EXACT [] +synonym: "sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity" RELATED [] +synonym: "transcription factor" BROAD [GOC:vw] +synonym: "transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" NARROW [] +synonym: "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW [] +synonym: "transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW [] +is_a: GO:0003700 ! DNA-binding transcription factor activity +relationship: has_part GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0006357 ! regulation of transcription by RNA polymerase II +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15530 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16131 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16152 xsd:anyURI +created_by: krc +creation_date: 2010-08-10T02:37:21Z + +[Term] +id: GO:0000984 +name: bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001017 +def: "Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase." [GOC:txnOH] +comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. +synonym: "bacterial-type RNA polymerase regulatory region DNA binding" RELATED [] +synonym: "eubacterial-type RNA polymerase regulatory region DNA binding" EXACT [] +synonym: "eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-10T02:58:18Z + +[Term] +id: GO:0000985 +name: bacterial-type RNA polymerase core promoter sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a bacterial gene." [GOC:pg, GOC:txnOH] +synonym: "eubacterial-type RNA polymerase core promoter sequence-specific DNA binding" EXACT [] +is_a: GO:0000984 ! bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding +is_a: GO:0001046 ! core promoter sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-10T03:01:38Z + +[Term] +id: GO:0000986 +name: bacterial-type cis-regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001150 +def: "Interacting selectively and non-covalently with a specific upstream cis-regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the promoter of a bacterial gene (or cistron, or operon)." [GOC:txnOH-2018] +synonym: "bacterial-type proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding" EXACT [] +synonym: "bacterial-type RNA polymerase enhancer sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding" NARROW [] +synonym: "eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding" EXACT [] +is_a: GO:0000984 ! bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding +is_a: GO:0000987 ! cis-regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2011-01-27T03:42:53Z + +[Term] +id: GO:0000987 +name: cis-regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001158 +alt_id: GO:0001159 +alt_id: GO:0035326 +def: "Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter." [GOC:txnOH-2018] +synonym: "cis-regulatory region binding" RELATED [] +synonym: "core promoter proximal region DNA binding" NARROW [] +synonym: "core promoter proximal region sequence-specific DNA binding" NARROW [] +synonym: "enhancer binding" RELATED [] +synonym: "enhancer sequence-specific DNA binding" RELATED [] +synonym: "promoter proximal region sequence-specific DNA binding" NARROW [] +synonym: "proximal promoter sequence-specific DNA binding" NARROW [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: bf +creation_date: 2010-02-26T10:17:00Z + +[Term] +id: GO:0000988 +name: obsolete transcription factor activity, protein binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "protein binding transcription factor activity" EXACT [] +synonym: "transcription factor activity" BROAD [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0005515 +consider: GO:0140110 +created_by: krc +creation_date: 2010-08-10T04:03:22Z + +[Term] +id: GO:0000989 +name: obsolete transcription factor activity, transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "transcription factor binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0008134 +consider: GO:0140110 +created_by: krc +creation_date: 2010-08-10T04:57:43Z + +[Term] +id: GO:0000990 +name: obsolete transcription factor activity, core RNA polymerase binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "core RNA polymerase binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0043175 +consider: GO:0140110 +created_by: krc +creation_date: 2010-08-10T05:01:03Z + +[Term] +id: GO:0000991 +name: obsolete transcription factor activity, core RNA polymerase II binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "core RNA polymerase II binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0000993 +consider: GO:0140110 +created_by: krc +creation_date: 2010-08-10T05:03:45Z + +[Term] +id: GO:0000992 +name: RNA polymerase III cis-regulatory region sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes." [GOC:txnOH, PMID:12381659] +is_a: GO:0000987 ! cis-regulatory region sequence-specific DNA binding +is_a: GO:0001016 ! RNA polymerase III transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-11T03:49:28Z + +[Term] +id: GO:0000993 +name: RNA polymerase II complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits." [GOC:txnOH] +synonym: "RNA polymerase II core binding" EXACT [] +synonym: "RNAP II core binding" EXACT [] +is_a: GO:0001099 ! basal RNA polymerase II transcription machinery binding +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-08-11T03:57:27Z + +[Term] +id: GO:0000994 +name: RNA polymerase III core binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits." [GOC:txnOH] +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-08-11T03:58:58Z + +[Term] +id: GO:0000995 +name: RNA polymerase III general transcription initiation factor activity +namespace: molecular_function +alt_id: GO:0001034 +def: "An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC." [GOC:txnOH-2018, PMID:12381659, Wikipedia:RNA_polymerase_III] +synonym: "core RNA polymerase III binding transcription factor activity" NARROW [] +synonym: "RNA polymerase III general initiation factor activity" EXACT [] +synonym: "RNA polymerase III transcription factor activity, sequence-specific DNA binding" NARROW [] +synonym: "sequence-specific DNA binding RNA polymerase III transcription factor activity" NARROW [] +synonym: "transcription factor activity, core RNA polymerase III binding" NARROW [] +is_a: GO:0140223 ! general transcription initiation factor activity +relationship: part_of GO:0006383 ! transcription by RNA polymerase III +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15789 xsd:anyURI +created_by: krc +creation_date: 2010-08-23T03:41:48Z + +[Term] +id: GO:0001000 +name: bacterial-type RNA polymerase core enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit." [GOC:txnOH] +comment: Should omega be included here? +synonym: "eubacterial-type RNA polymerase core enzyme binding" EXACT [] +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-08-17T04:59:00Z + +[Term] +id: GO:0001001 +name: mitochondrial single-subunit type RNA polymerase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6." [GOC:txnOH, PMID:20701995, PMID:2088182] +is_a: GO:0001050 ! single-subunit type RNA polymerase binding +created_by: krc +creation_date: 2010-08-17T05:01:28Z + +[Term] +id: GO:0001002 +name: RNA polymerase III type 1 promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001030 +def: "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition." [GOC:txnOH, PMID:12381659] +synonym: "RNA polymerase III type 1 promoter DNA binding" RELATED [] +is_a: GO:0000992 ! RNA polymerase III cis-regulatory region sequence-specific DNA binding +is_a: GO:0080084 ! 5S rDNA binding +created_by: krc +creation_date: 2010-08-18T05:38:20Z + +[Term] +id: GO:0001003 +name: RNA polymerase III type 2 promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001031 +def: "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs." [GOC:txnOH, PMID:12381659] +synonym: "RNA polymerase III type 2 promoter DNA binding" RELATED [] +is_a: GO:0000992 ! RNA polymerase III cis-regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-18T05:51:18Z + +[Term] +id: GO:0001004 +name: obsolete RNA polymerase III transcription regulator recruiting activity +namespace: molecular_function +alt_id: GO:0001005 +alt_id: GO:0001008 +alt_id: GO:0001033 +alt_id: GO:0001038 +alt_id: GO:0001157 +def: "OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB." [GOC:txnOH-2018, PMID:12381659, PMID:23063749, PMID:27911719, Wikipedia:RNA_polymerase_III] +comment: The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'. +synonym: "RNA polymerase III assembly factor activity" RELATED [] +synonym: "RNA polymerase III assembly factor activity, TFIIIB recruiting" RELATED [] +synonym: "RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity" NARROW [] +synonym: "RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity" NARROW [] +synonym: "RNA polymerase III transcription factor recruiting activity" EXACT [] +synonym: "RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity" NARROW [] +synonym: "RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity" NARROW [] +synonym: "RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity" NARROW [] +synonym: "SNAPc-type activity" RELATED [] +synonym: "TFIIIA activity" RELATED [] +synonym: "TFIIIC-type activity" RELATED [] +synonym: "transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting" EXACT [] +synonym: "transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting" NARROW [] +synonym: "transcription factor activity, RNA polymerase III type 1 promoter TFIIIB" RELATED [] +synonym: "transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting" NARROW [] +synonym: "transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting" NARROW [] +synonym: "type 2 RNA polymerase III promoter recognition" NARROW [] +synonym: "type 3 RNA polymerase III promoter recognition" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14852 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18561 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2010-08-18T05:53:32Z + +[Term] +id: GO:0001006 +name: RNA polymerase III type 3 promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001032 +def: "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae." [GOC:txnOH, PMID:12381659] +synonym: "RNA polymerase III type 3 promoter DNA binding" RELATED [] +is_a: GO:0000992 ! RNA polymerase III cis-regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-18T06:02:26Z + +[Term] +id: GO:0001007 +name: obsolete transcription factor activity, RNA polymerase III transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase III transcription factor binding transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2010-08-18T06:24:07Z + +[Term] +id: GO:0001010 +name: RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity +namespace: molecular_function +def: "The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions." [GOC:txnOH] +synonym: "sequence-specific DNA binding transcription factor recruiting transcription factor activity" EXACT [] +synonym: "transcription factor activity, sequence-specific DNA binding transcription factor recruiting" EXACT [] +synonym: "transcription factor activity, sequence-specific DNA-binding transcription factor recruiting" RELATED [] +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding +created_by: krc +creation_date: 2010-08-18T06:46:33Z + +[Term] +id: GO:0001011 +name: obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC)." [GOC:txnOH] +comment: This term was obsoleted because it was not clearly defined and usage has been inconsistent. +synonym: "sequence-specific DNA binding RNA polymerase recruiting transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0140223 +created_by: krc +creation_date: 2010-08-18T06:49:16Z + +[Term] +id: GO:0001014 +name: snoRNA transcription by RNA polymerase III +namespace: biological_process +def: "The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter." [GOC:txnOH] +synonym: "snoRNA transcription from a type 2 RNA polymerase III promoter" NARROW [] +is_a: GO:0006383 ! transcription by RNA polymerase III +is_a: GO:0009302 ! snoRNA transcription +created_by: krc +creation_date: 2010-08-18T07:13:45Z + +[Term] +id: GO:0001015 +name: snoRNA transcription by RNA polymerase II +namespace: biological_process +def: "The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter." [GOC:txnOH] +synonym: "snoRNA transcription from an RNA polymerase II promoter" EXACT [] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:0009302 ! snoRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: krc +creation_date: 2010-08-18T07:21:18Z + +[Term] +id: GO:0001016 +name: RNA polymerase III transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors." [GOC:txnOH, GOC:vw, PMID:12381659] +synonym: "RNA polymerase III regulatory region DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-19T09:36:17Z + +[Term] +id: GO:0001018 +name: mitochondrial promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0000997 +alt_id: GO:0001044 +alt_id: GO:0001045 +alt_id: GO:0070361 +alt_id: GO:0070362 +alt_id: GO:0070363 +alt_id: GO:0070364 +def: "Interacting selectively and non-covalently with a DNA region that controls the transcription of the mitochondrial DNA." [GOC:txnOH, GOC:vw, PMID:20056105] +synonym: "HSP coding strand binding" NARROW [PMID:9485316] +synonym: "HSP non-coding strand binding" NARROW [PMID:9485316] +synonym: "HSPas binding" NARROW [PMID:9485316] +synonym: "HSPs binding" NARROW [PMID:9485316] +synonym: "LSP coding strand binding" NARROW [PMID:9485316] +synonym: "LSP non-coding strand binding" NARROW [PMID:9485316] +synonym: "LSPas binding" NARROW [PMID:9485316] +synonym: "LSPs binding" NARROW [PMID:9485316] +synonym: "mitochondrial heavy strand promoter anti-sense binding" NARROW [] +synonym: "mitochondrial heavy strand promoter sense binding" NARROW [] +synonym: "mitochondrial light strand promoter anti-sense binding" NARROW [] +synonym: "mitochondrial light strand promoter sense binding" NARROW [] +synonym: "mitochondrial proximal promoter sequence-specific DNA binding" RELATED [] +synonym: "mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding" RELATED [] +synonym: "mitochondrial RNA polymerase core promoter sequence-specific DNA binding" RELATED [] +synonym: "mitochondrial RNA polymerase regulatory region DNA binding" RELATED [] +synonym: "mitochondrial RNA polymerase regulatory region sequence-specific DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-25T04:11:49Z + +[Term] +id: GO:0001019 +name: plastid promoter transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors." [GOC:txnOH, GOC:vw] +comment: plastid promoter regulatory region sequence-specific DNA binding +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-19T09:46:27Z + +[Term] +id: GO:0001025 +name: RNA polymerase III general transcription initiation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase III transcription factor, any protein required to initiate or regulate transcription by RNA polymerase III." [GOC:txnOH] +synonym: "RNA polymerase III transcription factor binding" BROAD [] +is_a: GO:0140296 ! general transcription initiation factor binding +created_by: krc +creation_date: 2010-08-20T03:26:50Z + +[Term] +id: GO:0001026 +name: obsolete TFIIIB-type transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex." [GOC:txnOH] +comment: This term was obsoleted because it represents a gene product. +synonym: "RNA polymerase III recruiting transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2010-08-23T12:24:31Z + +[Term] +id: GO:0001027 +name: obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex." [GOC:txnOH-2018, PMID:12381659] +comment: The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter. +synonym: "RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity" RELATED [] +is_obsolete: true +created_by: krc +creation_date: 2010-08-23T12:50:20Z + +[Term] +id: GO:0001028 +name: obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex." [GOC:txnOH-2018, PMID:12381659] +comment: The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter. +synonym: "RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity" RELATED [] +is_obsolete: true +created_by: krc +creation_date: 2010-08-23T12:52:01Z + +[Term] +id: GO:0001029 +name: obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex." [GOC:txnOH-2018, PMID:12381659] +synonym: "RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity" RELATED [] +is_obsolete: true +created_by: krc +creation_date: 2010-08-23T12:52:40Z + +[Term] +id: GO:0001039 +name: RNA polymerase III hybrid type promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001037 +def: "Interacting selectively and non-covalently with a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene." [GOC:txnOH, PMID:12381659] +synonym: "RNA polymerase III hybrid type promoter DNA binding" RELATED [] +is_a: GO:0000992 ! RNA polymerase III cis-regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2010-08-23T06:21:24Z + +[Term] +id: GO:0001040 +name: obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex." [GOC:txnOH-2018, PMID:12381659] +comment: The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter. +is_obsolete: true +created_by: krc +creation_date: 2010-08-23T06:28:23Z + +[Term] +id: GO:0001042 +name: RNA polymerase I core binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits." [GOC:txnOH] +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-09-23T01:39:23Z + +[Term] +id: GO:0001046 +name: core promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001047 +def: "Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon." [GOC:pg, GOC:txnOH] +synonym: "core promoter binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19312 xsd:anyURI +created_by: krc +creation_date: 2010-08-25T04:17:44Z + +[Term] +id: GO:0001048 +name: RNA polymerase IV core binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production." [GOC:txnOH, PMID:19110459] +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-09-23T01:41:03Z + +[Term] +id: GO:0001049 +name: RNA polymerase V core binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing." [GOC:txnOH, PMID:19110459] +is_a: GO:0043175 ! RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-09-23T01:41:08Z + +[Term] +id: GO:0001050 +name: single-subunit type RNA polymerase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6." [GOC:txnOH, PMID:20701995] +synonym: "SP6-type RNA polymerase binding" EXACT [] +synonym: "T3-type RNA polymerase binding" EXACT [] +synonym: "T3/T7 type RNA polymerase binding" EXACT [] +synonym: "T7-type RNA polymerase binding" EXACT [] +is_a: GO:0070063 ! RNA polymerase binding +created_by: krc +creation_date: 2010-09-23T02:33:45Z + +[Term] +id: GO:0001051 +name: plastid single-subunit type RNA polymerase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6." [GOC:txnOH, PMID:20701995] +is_a: GO:0001050 ! single-subunit type RNA polymerase binding +created_by: krc +creation_date: 2010-09-23T02:42:57Z + +[Term] +id: GO:0001052 +name: plastid PEP RNA polymerase core enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit." [GOC:txnOH, PMID:20701995] +is_a: GO:0001000 ! bacterial-type RNA polymerase core enzyme binding +created_by: krc +creation_date: 2010-09-23T02:49:31Z + +[Term] +id: GO:0001054 +name: RNA polymerase I activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter" EXACT [] +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: part_of GO:0006360 ! transcription by RNA polymerase I +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0006360 ! transcription by RNA polymerase I +created_by: krc +creation_date: 2010-09-23T03:36:11Z + +[Term] +id: GO:0001055 +name: RNA polymerase II activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter" EXACT [] +xref: Reactome:R-HSA-6814549 "Pre-snRNA transcript initiation, Integrator binding, LEC binding" +xref: Reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine" +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: part_of GO:0006366 ! transcription by RNA polymerase II +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0006366 ! transcription by RNA polymerase II +created_by: krc +creation_date: 2010-09-23T03:44:23Z + +[Term] +id: GO:0001056 +name: RNA polymerase III activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [] +xref: Reactome:R-HSA-1964482 "RNA polymerase III transcribes microbial dsDNA to dsRNA" +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: part_of GO:0006383 ! transcription by RNA polymerase III +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0006383 ! transcription by RNA polymerase III +created_by: krc +creation_date: 2010-09-23T03:44:47Z + +[Term] +id: GO:0001057 +name: RNA polymerase IV activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter" EXACT [] +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: part_of GO:0001059 ! transcription by RNA polymerase IV +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0001059 ! transcription by RNA polymerase IV +created_by: krc +creation_date: 2010-09-23T03:44:55Z + +[Term] +id: GO:0001058 +name: RNA polymerase V activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter" EXACT [] +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +intersection_of: part_of GO:0001060 ! transcription by RNA polymerase V +relationship: occurs_in GO:0000790 ! nuclear chromatin +relationship: part_of GO:0001060 ! transcription by RNA polymerase V +created_by: krc +creation_date: 2010-09-23T03:45:01Z + +[Term] +id: GO:0001059 +name: transcription by RNA polymerase IV +namespace: biological_process +def: "The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter." [GOC:txnOH, PMID:19110459] +synonym: "transcription from RNA pol IV promoter" EXACT [] +synonym: "transcription from RNA polymerase IV promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: krc +creation_date: 2010-09-23T03:51:35Z + +[Term] +id: GO:0001060 +name: transcription by RNA polymerase V +namespace: biological_process +def: "The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter." [GOC:txnOH, PMID:19110459] +synonym: "transcription from RNA pol V promoter" EXACT [] +synonym: "transcription from RNA polymerase V promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: krc +creation_date: 2010-09-23T03:54:04Z + +[Term] +id: GO:0001061 +name: bacterial-type RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +relationship: part_of GO:0001121 ! bacterial transcription +created_by: krc +creation_date: 2010-10-19T03:36:01Z + +[Term] +id: GO:0001062 +name: plastid PEP-A RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH, PMID:20701995] +is_a: GO:0001061 ! bacterial-type RNA polymerase activity +relationship: part_of GO:0042793 ! plastid transcription +created_by: krc +creation_date: 2010-10-19T03:38:49Z + +[Term] +id: GO:0001063 +name: plastid PEP-B RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH, PMID:20701995] +is_a: GO:0001061 ! bacterial-type RNA polymerase activity +relationship: part_of GO:0042793 ! plastid transcription +created_by: krc +creation_date: 2010-10-19T03:46:46Z + +[Term] +id: GO:0001064 +name: single subunit type RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +synonym: "T3/T7 type RNA polymerase activity" EXACT [] +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +created_by: krc +creation_date: 2010-10-19T03:47:56Z + +[Term] +id: GO:0001065 +name: mitochondrial single subunit type RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH] +is_a: GO:0001064 ! single subunit type RNA polymerase activity +relationship: part_of GO:0006390 ! mitochondrial transcription +created_by: krc +creation_date: 2010-10-19T03:50:51Z + +[Term] +id: GO:0001066 +name: plastid single subunit type RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [GOC:txnOH, PMID:20701995] +is_a: GO:0001064 ! single subunit type RNA polymerase activity +relationship: part_of GO:0042793 ! plastid transcription +created_by: krc +creation_date: 2010-10-19T03:54:57Z + +[Term] +id: GO:0001067 +name: regulatory region nucleic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair." [GOC:txnOH] +is_a: GO:0003676 ! nucleic acid binding +created_by: krc +creation_date: 2010-10-21T04:08:56Z + +[Term] +id: GO:0001068 +name: transcription regulatory region RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RNA region within the transcript that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon." [GOC:txnOH] +is_a: GO:0001069 ! regulatory region RNA binding +created_by: krc +creation_date: 2010-10-21T04:15:32Z + +[Term] +id: GO:0001069 +name: regulatory region RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair." [GOC:txnOH] +is_a: GO:0001067 ! regulatory region nucleic acid binding +is_a: GO:0003723 ! RNA binding +created_by: krc +creation_date: 2010-10-21T04:17:01Z + +[Term] +id: GO:0001070 +name: RNA-binding transcription regulator activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA sequence in order to modulate transcription. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences." [GOC:txnOH-2018, PMID:1756726] +synonym: "RNA binding transcription factor activity" RELATED [] +synonym: "RNA binding transcription regulator activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: has_part GO:0001068 ! transcription regulatory region RNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14872 xsd:anyURI +created_by: krc +creation_date: 2010-10-21T04:19:17Z + +[Term] +id: GO:0001072 +name: transcription antitermination factor activity, RNA binding +namespace: molecular_function +def: "Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein." [GOC:txnOH, PMID:8332211] +synonym: "RNA binding transcription antitermination factor activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: part_of GO:0031564 ! transcription antitermination +property_value: RO:0002161 NCBITaxon:2759 +created_by: krc +creation_date: 2010-10-21T04:48:17Z + +[Term] +id: GO:0001073 +name: transcription antitermination factor activity, DNA binding +namespace: molecular_function +def: "Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein." [GOC:txnOH, PMID:8332211] +synonym: "DNA binding transcription antitermination factor activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: part_of GO:0031564 ! transcription antitermination +created_by: krc +creation_date: 2010-10-21T05:18:52Z + +[Term] +id: GO:0001074 +name: obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter." [GOC:txnOH] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" EXACT [] +synonym: "transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16554 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2010-10-22T02:30:43Z + +[Term] +id: GO:0001076 +name: obsolete transcription factor activity, RNA polymerase II transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "RNA polymerase II transcription factor binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0001085 +consider: GO:0140110 +created_by: krc +creation_date: 2010-10-22T02:49:32Z + +[Term] +id: GO:0001079 +name: nitrogen catabolite regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:txnOH, PMID:19104072] +synonym: "regulation of transcription from RNA polymerase II promoter by nitrogen catabolites" EXACT [GOC:mah] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0090293 ! nitrogen catabolite regulation of transcription +created_by: krc +creation_date: 2010-10-27T03:29:01Z + +[Term] +id: GO:0001080 +name: nitrogen catabolite activation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:txnOH, PMID:19104072] +synonym: "positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites" EXACT [GOC:mah] +is_a: GO:0001079 ! nitrogen catabolite regulation of transcription from RNA polymerase II promoter +is_a: GO:0090294 ! nitrogen catabolite activation of transcription +created_by: krc +creation_date: 2010-10-27T03:32:34Z + +[Term] +id: GO:0001081 +name: nitrogen catabolite repression of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:txnOH, PMID:19104072] +synonym: "negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites" EXACT [GOC:mah] +is_a: GO:0001079 ! nitrogen catabolite regulation of transcription from RNA polymerase II promoter +is_a: GO:0090295 ! nitrogen catabolite repression of transcription +created_by: krc +creation_date: 2010-10-27T03:38:05Z + +[Term] +id: GO:0001082 +name: obsolete transcription factor activity, RNA polymerase I transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase I transcription factor binding transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2010-10-27T04:03:47Z + +[Term] +id: GO:0001083 +name: obsolete transcription factor activity, RNA polymerase II basal transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase II basal transcription factor binding transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2010-10-27T04:12:55Z + +[Term] +id: GO:0001084 +name: obsolete transcription factor activity, TFIID-class binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIID-class binding transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001094 +created_by: krc +creation_date: 2010-10-27T04:15:22Z + +[Term] +id: GO:0001085 +name: RNA polymerase II transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II." [GOC:txnOH] +is_a: GO:0008134 ! transcription factor binding +created_by: krc +creation_date: 2010-10-28T02:08:59Z + +[Term] +id: GO:0001086 +name: obsolete transcription factor activity, TFIIA-class binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIIA-class binding transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001092 +created_by: krc +creation_date: 2010-10-28T02:14:59Z + +[Term] +id: GO:0001087 +name: obsolete transcription factor activity, TFIIB-class binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIIB-class binding transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001093 +created_by: krc +creation_date: 2010-10-28T02:18:00Z + +[Term] +id: GO:0001088 +name: obsolete transcription factor activity, TFIIE-class binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIIE-class binding transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001095 +created_by: krc +creation_date: 2010-10-28T02:25:22Z + +[Term] +id: GO:0001089 +name: obsolete transcription factor activity, TFIIF-class transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIIF-class binding transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001096 +created_by: krc +creation_date: 2010-10-28T02:27:12Z + +[Term] +id: GO:0001090 +name: obsolete transcription factor activity, TFIIH-class binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "TFIIH-class binding transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2010-10-28T02:28:01Z + +[Term] +id: GO:0001091 +name: RNA polymerase II general transcription initiation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor." [GOC:txnOH, PMID:16858867] +synonym: "RNA polymerase II basal transcription factor binding" EXACT [] +is_a: GO:0001099 ! basal RNA polymerase II transcription machinery binding +is_a: GO:0140296 ! general transcription initiation factor binding +created_by: krc +creation_date: 2010-10-28T02:30:02Z + +[Term] +id: GO:0001092 +name: TFIIA-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor." [GOC:krc, PMID:16858867] +synonym: "TFIIA-class transcription factor binding" EXACT [] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2010-10-28T02:37:19Z + +[Term] +id: GO:0001093 +name: TFIIB-class transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II." [GOC:krc, PMID:16858867] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +created_by: krc +creation_date: 2010-10-28T02:46:15Z + +[Term] +id: GO:0001094 +name: TFIID-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II." [GOC:krc, PMID:16858867] +synonym: "TFIID-class transcription factor binding" EXACT [] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2010-10-28T02:48:33Z + +[Term] +id: GO:0001095 +name: TFIIE-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II." [GOC:krc, PMID:16858867] +synonym: "TFIIE-class transcription factor binding" EXACT [] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2010-10-28T02:49:20Z + +[Term] +id: GO:0001096 +name: TFIIF-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II." [GOC:krc, PMID:16858867] +synonym: "TFIIF-class transcription factor binding" EXACT [] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2010-10-28T02:51:20Z + +[Term] +id: GO:0001097 +name: TFIIH-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II." [GOC:krc, PMID:16858867] +synonym: "TFIIH-class transcription factor binding" EXACT [] +is_a: GO:0001091 ! RNA polymerase II general transcription initiation factor binding +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2010-10-28T02:51:41Z + +[Term] +id: GO:0001098 +name: basal transcription machinery binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase." [GOC:txnOH] +comment: Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors. +is_a: GO:0005515 ! protein binding +created_by: krc +creation_date: 2010-11-24T12:50:49Z + +[Term] +id: GO:0001099 +name: basal RNA polymerase II transcription machinery binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase." [GOC:txnOH] +comment: Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors. +synonym: "basal RNAP II transcription machinery binding" EXACT [] +is_a: GO:0001098 ! basal transcription machinery binding +created_by: krc +creation_date: 2010-11-24T12:54:33Z + +[Term] +id: GO:0001100 +name: negative regulation of exit from mitosis +namespace: biological_process +def: "Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:rn] +synonym: "down regulation of exit from mitosis" EXACT [] +synonym: "down-regulation of exit from mitosis" EXACT [] +synonym: "downregulation of exit from mitosis" EXACT [] +synonym: "inhibition of exit from mitosis" NARROW [] +is_a: GO:0007096 ! regulation of exit from mitosis +is_a: GO:0045839 ! negative regulation of mitotic nuclear division +is_a: GO:1901991 ! negative regulation of mitotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010458 ! exit from mitosis +relationship: negatively_regulates GO:0010458 ! exit from mitosis + +[Term] +id: GO:0001101 +name: response to acid chemical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn] +comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead. +subset: gocheck_do_not_manually_annotate +synonym: "response to acid" BROAD [] +synonym: "response to acid anion" RELATED [] +synonym: "response to oxoanion" RELATED [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0001102 +name: RNA polymerase II activating transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription." [GOC:txnOH] +is_a: GO:0033613 ! activating transcription factor binding +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding +created_by: krc +creation_date: 2010-11-24T02:17:08Z + +[Term] +id: GO:0001103 +name: RNA polymerase II repressing transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription." [GOC:txnOH] +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding +is_a: GO:0070491 ! repressing transcription factor binding +created_by: krc +creation_date: 2010-11-24T02:34:55Z + +[Term] +id: GO:0001108 +name: bacterial-type RNA polymerase holo enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase." [GOC:txnOH] +synonym: "basal bacterial-type RNA polymerase transcription machinery binding" EXACT [] +is_a: GO:0001098 ! basal transcription machinery binding +created_by: krc +creation_date: 2010-11-30T04:26:04Z + +[Term] +id: GO:0001109 +name: promoter clearance during DNA-templated transcription +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors." [GOC:txnOH, PMID:15020047, PMID:18280161] +synonym: "promoter clearance during DNA-dependent transcription" EXACT [GOC:txnOH] +synonym: "promoter escape" BROAD [] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: has_part GO:0001119 ! protein-DNA-RNA complex remodeling +relationship: part_of GO:0006351 ! transcription, DNA-templated +created_by: krc +creation_date: 2010-12-01T02:13:09Z + +[Term] +id: GO:0001110 +name: promoter clearance from RNA polymerase III promoter +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase." [GOC:txnOH] +is_a: GO:0001109 ! promoter clearance during DNA-templated transcription +relationship: part_of GO:0006383 ! transcription by RNA polymerase III +created_by: krc +creation_date: 2010-12-01T03:08:29Z + +[Term] +id: GO:0001111 +name: promoter clearance from RNA polymerase II promoter +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors." [GOC:txnOH, PMID:15020047] +synonym: "promoter escape from RNA polymerase II promoter" EXACT [] +is_a: GO:0001109 ! promoter clearance during DNA-templated transcription +relationship: part_of GO:0006366 ! transcription by RNA polymerase II +created_by: krc +creation_date: 2010-12-01T03:09:31Z + +[Term] +id: GO:0001112 +name: DNA-templated transcription open complex formation +namespace: biological_process +def: "Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble." [GOC:txnOH, PMID:15020047, PMID:18280161] +synonym: "DNA-dependent transcriptional open complex formation" EXACT [GOC:txnOH] +synonym: "DNA-templated transcriptional open complex formation" EXACT [] +synonym: "promoter melting" BROAD [] +is_a: GO:0001120 ! protein-DNA complex remodeling +relationship: part_of GO:0006352 ! DNA-templated transcription, initiation +created_by: krc +creation_date: 2010-12-02T02:15:04Z + +[Term] +id: GO:0001113 +name: transcription open complex formation at RNA polymerase II promoter +namespace: biological_process +def: "Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble." [GOC:txnOH, PMID:15020047, PMID:18280161] +synonym: "RNA polymerase II promoter melting" EXACT [] +synonym: "transcriptional open complex formation at RNA polymerase II promoter" EXACT [] +is_a: GO:0001112 ! DNA-templated transcription open complex formation +relationship: part_of GO:0006367 ! transcription initiation from RNA polymerase II promoter +created_by: krc +creation_date: 2010-12-02T02:27:19Z + +[Term] +id: GO:0001114 +name: protein-DNA-RNA complex +namespace: cellular_component +def: "A macromolecular complex containing protein, DNA, and RNA molecules." [GOC:txnOH] +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2010-12-03T02:09:38Z + +[Term] +id: GO:0001115 +name: protein-DNA-RNA complex subunit organization +namespace: biological_process +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex." [GOC:txnOH] +synonym: "protein-DNA-RNA complex subunit organisation" EXACT [GOC:mah] +is_a: GO:0043933 ! protein-containing complex subunit organization +created_by: krc +creation_date: 2010-12-03T04:00:02Z + +[Term] +id: GO:0001116 +name: protein-DNA-RNA complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex." [GOC:txnOH] +is_a: GO:0001115 ! protein-DNA-RNA complex subunit organization +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: krc +creation_date: 2010-12-03T04:01:38Z + +[Term] +id: GO:0001117 +name: protein-DNA-RNA complex disassembly +namespace: biological_process +def: "The disaggregation of a protein-DNA-RNA complex into its constituent components." [GOC:txnOH] +is_a: GO:0001115 ! protein-DNA-RNA complex subunit organization +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: krc +creation_date: 2010-12-03T04:04:07Z + +[Term] +id: GO:0001118 +name: transcription ternary complex disassembly +namespace: biological_process +def: "The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components." [GOC:txnOH] +synonym: "transcription protein-DNA-RNA complex disassembly" EXACT [] +is_a: GO:0001117 ! protein-DNA-RNA complex disassembly +relationship: part_of GO:0006353 ! DNA-templated transcription, termination +created_by: krc +creation_date: 2010-12-03T04:11:34Z + +[Term] +id: GO:0001119 +name: protein-DNA-RNA complex remodeling +namespace: biological_process +def: "The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex." [GOC:txnOH] +is_a: GO:0001115 ! protein-DNA-RNA complex subunit organization +is_a: GO:0034367 ! protein-containing complex remodeling +created_by: krc +creation_date: 2010-12-03T04:15:52Z + +[Term] +id: GO:0001120 +name: protein-DNA complex remodeling +namespace: biological_process +def: "The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex." [GOC:txnOH] +is_a: GO:0034367 ! protein-containing complex remodeling +is_a: GO:0071824 ! protein-DNA complex subunit organization +created_by: krc +creation_date: 2010-12-03T04:17:15Z + +[Term] +id: GO:0001121 +name: bacterial transcription +namespace: biological_process +def: "The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter." [GOC:txnOH] +synonym: "transcription from bacterial-type RNA polymerase promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: krc +creation_date: 2010-12-06T03:32:13Z + +[Term] +id: GO:0001122 +name: promoter clearance from bacterial-type RNA polymerase promoter +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phase of transcription by a bacterial-type RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance generally involves dissociation of the sigma initiation factor." [GOC:txnOH, PMID:18280161] +is_a: GO:0001109 ! promoter clearance during DNA-templated transcription +relationship: part_of GO:0001121 ! bacterial transcription +created_by: krc +creation_date: 2010-12-06T03:38:10Z + +[Term] +id: GO:0001123 +name: transcription initiation from bacterial-type RNA polymerase promoter +namespace: biological_process +def: "Any process involved in the assembly of bacterial-type RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription." [GOC:txnOH, PMID:18280161] +is_a: GO:0006352 ! DNA-templated transcription, initiation +relationship: part_of GO:0001121 ! bacterial transcription +created_by: krc +creation_date: 2010-12-06T03:40:12Z + +[Term] +id: GO:0001124 +name: transcription elongation from bacterial-type RNA polymerase promoter +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at a bacterial-type RNA polymerase promoter by the addition of ribonucleotides catalyzed by a bacterial-type RNA polymerase." [GOC:txnOH, PMID:18280161] +synonym: "RNA elongation from bacterial-type RNA polymerase promoter" EXACT [] +is_a: GO:0006354 ! DNA-templated transcription, elongation +relationship: part_of GO:0001121 ! bacterial transcription +created_by: krc +creation_date: 2010-12-06T03:46:27Z + +[Term] +id: GO:0001125 +name: transcription termination from bacterial-type RNA polymerase promoter +namespace: biological_process +def: "The process in which the synthesis of an RNA molecule by a bacterial-type RNA polymerase using a DNA template is completed." [GOC:txnOH, PMID:18280161] +is_a: GO:0006353 ! DNA-templated transcription, termination +relationship: part_of GO:0001121 ! bacterial transcription +created_by: krc +creation_date: 2010-12-06T03:47:43Z + +[Term] +id: GO:0001126 +name: bacterial-type RNA polymerase preinitiation complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on a bacterial-type RNA polymerase promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription." [GOC:txnOH, PMID:18280161] +synonym: "bacterial-type RNA polymerase transcription PIC biosynthesis" EXACT [] +synonym: "bacterial-type RNA polymerase transcription PIC formation" EXACT [] +synonym: "bacterial-type RNA polymerase transcriptional preinitiation complex formation" EXACT [] +is_a: GO:0070897 ! transcription preinitiation complex assembly +relationship: part_of GO:0001123 ! transcription initiation from bacterial-type RNA polymerase promoter +created_by: krc +creation_date: 2010-12-06T03:54:45Z + +[Term] +id: GO:0001127 +name: transcription open complex formation at bacterial-type RNA polymerase promoter +namespace: biological_process +def: "Any process involved in the melting of the DNA hybrid of the core promoter region within a bacterial-type RNA polymerase promoter to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble." [GOC:txnOH, PMID:18280161] +synonym: "transcriptional open complex formation at bacterial-type RNA polymerase promoter" EXACT [] +is_a: GO:0001112 ! DNA-templated transcription open complex formation +relationship: part_of GO:0001123 ! transcription initiation from bacterial-type RNA polymerase promoter +created_by: krc +creation_date: 2010-12-06T04:04:16Z + +[Term] +id: GO:0001128 +name: obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery." [GOC:txnOH, PMID:16858867] +comment: This term was obsoleted because it represented a mix of function and process and is not annotated consistently +synonym: "RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2011-01-20T02:13:36Z + +[Term] +id: GO:0001129 +name: obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase." [GOC:txnOH, PMID:16858867] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly" NARROW [] +synonym: "TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-01-20T02:53:35Z + +[Term] +id: GO:0001132 +name: obsolete RNA polymerase II transcription factor activity, TBP-class protein binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well." [GOC:txnOH, PMID:16858867] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "TATA-binding protein binding RNA polymerase II transcription factor activity" NARROW [] +synonym: "TBP-class protein binding RNA polymerase II transcription factor activity" EXACT [] +synonym: "TRF protein binding RNA polymerase II transcription factor activity" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-01-20T04:15:44Z + +[Term] +id: GO:0001134 +name: obsolete transcription regulator recruiting activity +namespace: molecular_function +def: "OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation." [GOC:txnOH-2018, PMID:16858867] +comment: The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'. +synonym: "transcription factor activity, transcription factor recruiting" RELATED [] +synonym: "transcription factor recruiting activity" EXACT [] +synonym: "transcription factor recruiting transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15577 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18561 xsd:anyURI +is_obsolete: true +replaced_by: GO:0003712 +created_by: krc +creation_date: 2011-01-20T04:57:59Z + +[Term] +id: GO:0001135 +name: obsolete RNA polymerase II transcription regulator recruiting activity +namespace: molecular_function +alt_id: GO:0001136 +alt_id: GO:0001137 +alt_id: GO:0001138 +def: "OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation." [GOC:txnOH-2018, PMID:16858867] +comment: The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'. +synonym: "RNA polymerase II transcription factor recruiting activity" EXACT [] +synonym: "RNA polymerase II transcription factor recruiting transcription factor activity" EXACT [] +synonym: "TFIIE-class transcription factor recruiting transcription factor activity" NARROW [] +synonym: "TFIIF-class transcription factor recruiting transcription factor activity" NARROW [] +synonym: "TFIIH-class transcription factor recruiting transcription factor activity" NARROW [] +synonym: "transcription factor activity, RNA polymerase II transcription factor recruiting" RELATED [] +synonym: "transcription factor activity, TFIIE-class transcription factor recruiting" NARROW [] +synonym: "transcription factor activity, TFIIF-class transcription factor recruiting" NARROW [] +synonym: "transcription factor activity, TFIIH-class transcription factor recruiting" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15795 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18561 xsd:anyURI +is_obsolete: true +replaced_by: GO:0003712 +created_by: krc +creation_date: 2011-01-20T05:13:12Z + +[Term] +id: GO:0001139 +name: RNA polymerase II complex recruiting activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase." [GOC:txnOH, PMID:16858867] +synonym: "core RNA polymerase II recruiting transcription factor activity" EXACT [] +synonym: "transcription factor activity, core RNA polymerase II recruiting" RELATED [] +is_a: GO:0000993 ! RNA polymerase II complex binding +relationship: part_of GO:0051123 ! RNA polymerase II preinitiation complex assembly +created_by: krc +creation_date: 2011-01-20T05:55:01Z + +[Term] +id: GO:0001145 +name: mitochondrial RNA polymerase termination site sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001146 +def: "Interacting selectively and non-covalently with a DNA sequence that controls mitochondrial transcription termination." [GOC:txnOH-2018, PMID:18391175] +synonym: "mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding" EXACT [] +is_a: GO:0001147 ! transcription termination site sequence-specific DNA binding +relationship: part_of GO:0006393 ! termination of mitochondrial transcription +created_by: krc +creation_date: 2011-01-27T02:42:23Z + +[Term] +id: GO:0001147 +name: transcription termination site sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001160 +def: "Interacting selectively and non-covalently with a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon." [GOC:txnOH, PMID:18280161, PMID:18391175] +comment: Transcription termination sites can be recognized by the RNA polymerase (RNAP) itself or by another protein which interacts with the RNAP to promote transcription termination. Note that not all genes have a specific sequence that functions as a termination site; for most mRNAs transcribed by RNAP II termination is not mediated by a specific termination sequence, but is coupled to polyadenylation. +synonym: "transcription termination site DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2011-01-27T02:48:26Z + +[Term] +id: GO:0001148 +name: bacterial-type RNA polymerase termination site sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence of DNA that is a terminator for bacterial-type RNA polymerase." [GOC:txnOH, PMID:18280161] +is_a: GO:0000984 ! bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding +is_a: GO:0001147 ! transcription termination site sequence-specific DNA binding +created_by: krc +creation_date: 2011-01-27T03:04:07Z + +[Term] +id: GO:0001149 +name: obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase." [GOC:txnOH, PMID:18280161] +synonym: "bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16730 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-01-27T03:08:41Z + +[Term] +id: GO:0001152 +name: obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting +namespace: molecular_function +def: "OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter." [GOC:txnOH, PMID:12381659] +comment: This term was made obsolete in the 2018 Transcription branch revision. This represents the activity of TFIIIA only. +synonym: "RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity" EXACT [] +synonym: "TFIIIA activity" RELATED [] +synonym: "type 1 RNA polymerase III promoter recognition" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2011-01-27T04:18:21Z + +[Term] +id: GO:0001153 +name: obsolete transcription factor activity, RNA polymerase III transcription factor recruiting +namespace: molecular_function +def: "OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III." [GOC:txnOH] +comment: This term was made obsolete in the 2018 Transcription branch revision. This term was redundant with other terms. +synonym: "RNA polymerase III transcription factor recruiting transcription factor activity" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2011-01-27T04:45:37Z + +[Term] +id: GO:0001154 +name: TFIIIB-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III." [GOC:txnOH, PMID:12381659] +synonym: "TFIIIB-class transcription factor binding" EXACT [] +is_a: GO:0001025 ! RNA polymerase III general transcription initiation factor binding +created_by: krc +creation_date: 2011-01-27T04:53:50Z + +[Term] +id: GO:0001155 +name: TFIIIA-class transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters." [GOC:txnOH, PMID:12381659] +is_a: GO:0001025 ! RNA polymerase III general transcription initiation factor binding +created_by: krc +creation_date: 2011-01-27T04:57:49Z + +[Term] +id: GO:0001156 +name: TFIIIC-class transcription factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III." [GOC:txnOH, PMID:12381659] +synonym: "TFIIIC-class transcription factor binding" EXACT [] +is_a: GO:0001025 ! RNA polymerase III general transcription initiation factor binding +created_by: krc +creation_date: 2011-01-27T05:02:22Z + +[Term] +id: GO:0001161 +name: intronic transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0044213 +def: "Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcription of the transcript it is contained within." [GOC:txnOH] +comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. +synonym: "intronic transcription regulatory region DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19312 xsd:anyURI +created_by: krc +creation_date: 2011-01-28T03:44:02Z + +[Term] +id: GO:0001162 +name: RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within." [GOC:txnOH] +comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. +is_a: GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +is_a: GO:0001161 ! intronic transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2011-01-28T03:46:19Z + +[Term] +id: GO:0001163 +name: RNA polymerase I transcription regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001013 +def: "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I." [GOC:txnOH] +synonym: "RNA polymerase I regulatory region DNA binding" RELATED [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19312 xsd:anyURI +created_by: krc +creation_date: 2011-01-31T04:12:06Z + +[Term] +id: GO:0001164 +name: RNA polymerase I core promoter sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001187 +def: "Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE." [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832] +synonym: "RNA polymerase I CORE element sequence-specific DNA binding" EXACT [] +synonym: "RNA polymerase I core element sequence-specific DNA binding" EXACT [] +synonym: "RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity" RELATED [] +synonym: "RNA polymerase I core promoter sequence-specific DNA binding" EXACT [] +synonym: "transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting" RELATED [] +is_a: GO:0001046 ! core promoter sequence-specific DNA binding +is_a: GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +relationship: part_of GO:0001188 ! RNA polymerase I preinitiation complex assembly +created_by: krc +creation_date: 2011-01-31T04:47:48Z + +[Term] +id: GO:0001165 +name: RNA polymerase I cis-regulatory region sequence-specific DNA binding +namespace: molecular_function +alt_id: GO:0001166 +def: "Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element)." [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832] +synonym: "RNA polymerase I enhancer sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase I upstream control element sequence-specific DNA binding" RELATED [] +synonym: "RNA polymerase I upstream element sequence-specific DNA binding" RELATED [] +is_a: GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +created_by: krc +creation_date: 2011-01-31T05:29:59Z + +[Term] +id: GO:0001167 +name: obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex." [GOC:txnOH] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "sequence-specific DNA binding RNA polymerase I transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15787 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-02-03T04:07:46Z + +[Term] +id: GO:0001168 +name: obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I." [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15787 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-02-03T04:10:23Z + +[Term] +id: GO:0001169 +name: obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I." [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "RNA polymerase I core promoter sequence-specific DNA binding transcription factor" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15787 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-02-03T04:10:42Z + +[Term] +id: GO:0001170 +name: obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I." [GOC:txnOH, PMID:12865296, PMID:14969726, PMID:8057832] +comment: This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child. +synonym: "RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15787 xsd:anyURI +is_obsolete: true +created_by: krc +creation_date: 2011-02-03T04:10:59Z + +[Term] +id: GO:0001171 +name: reverse transcription +namespace: biological_process +def: "A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis." [GOC:txnOH, PMID:20358252] +xref: Wikipedia:Reverse_transcription +is_a: GO:0006278 ! RNA-dependent DNA biosynthetic process +relationship: has_part GO:0003964 ! RNA-directed DNA polymerase activity +relationship: has_part GO:0004533 ! exoribonuclease H activity +created_by: krc +creation_date: 2011-03-14T03:51:08Z + +[Term] +id: GO:0001172 +name: transcription, RNA-templated +namespace: biological_process +def: "The cellular synthesis of RNA on a template of RNA." [GOC:txnOH] +synonym: "transcription, RNA-dependent" EXACT [GOC:txnOH] +is_a: GO:0097659 ! nucleic acid-templated transcription +created_by: krc +creation_date: 2011-03-14T03:54:46Z + +[Term] +id: GO:0001173 +name: DNA-templated transcriptional start site selection +namespace: biological_process +def: "Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript." [GOC:txnOH, PMID:16826228, PMID:18846104] +synonym: "DNA-dependent transcriptional start site selection" EXACT [GOC:txnOH] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006352 ! DNA-templated transcription, initiation +created_by: krc +creation_date: 2011-06-20T12:44:11Z + +[Term] +id: GO:0001174 +name: transcriptional start site selection at RNA polymerase II promoter +namespace: biological_process +def: "Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript." [GOC:txnOH, PMID:16826228, PMID:18846104] +is_a: GO:0001173 ! DNA-templated transcriptional start site selection +relationship: part_of GO:0006367 ! transcription initiation from RNA polymerase II promoter +created_by: krc +creation_date: 2011-06-20T01:35:28Z + +[Term] +id: GO:0001175 +name: transcriptional start site selection at RNA polymerase III promoter +namespace: biological_process +def: "Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript." [GOC:txnOH] +is_a: GO:0001173 ! DNA-templated transcriptional start site selection +relationship: part_of GO:0006384 ! transcription initiation from RNA polymerase III promoter +created_by: krc +creation_date: 2011-06-20T01:47:38Z + +[Term] +id: GO:0001176 +name: transcriptional start site selection at bacterial-type RNA polymerase promoter +namespace: biological_process +def: "Any process involved in the selection of the specific location within the template strand of a bacterial-type RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript." [GOC:txnOH] +is_a: GO:0001173 ! DNA-templated transcriptional start site selection +relationship: part_of GO:0001123 ! transcription initiation from bacterial-type RNA polymerase promoter +created_by: krc +creation_date: 2011-06-20T01:48:56Z + +[Term] +id: GO:0001177 +name: regulation of transcription open complex formation at RNA polymerase II promoter +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble." [GOC:txnOH] +synonym: "regulation of transcriptional open complex formation at RNA polymerase II promoter" EXACT [] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001113 ! transcription open complex formation at RNA polymerase II promoter +relationship: regulates GO:0001113 ! transcription open complex formation at RNA polymerase II promoter +created_by: krc +creation_date: 2011-06-20T02:01:18Z + +[Term] +id: GO:0001178 +name: regulation of transcriptional start site selection at RNA polymerase II promoter +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript." [GOC:txnOH] +synonym: "regulation of transcription start site selection at RNA polymerase II promoter" EXACT [] +synonym: "regulation of transcriptional start site selection at RNA polymerase II promoter" EXACT [] +is_a: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001174 ! transcriptional start site selection at RNA polymerase II promoter +relationship: regulates GO:0001174 ! transcriptional start site selection at RNA polymerase II promoter +created_by: krc +creation_date: 2011-06-20T02:06:00Z + +[Term] +id: GO:0001179 +name: RNA polymerase I general transcription initiation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase I transcription factor, any protein required to initiate or regulate transcription by RNA polymerase I." [GOC:txnOH] +synonym: "RNA polymerase I transcription factor binding" BROAD [] +is_a: GO:0140296 ! general transcription initiation factor binding +created_by: krc +creation_date: 2011-08-12T03:03:03Z + +[Term] +id: GO:0001181 +name: RNA polymerase I general transcription initiation factor activity +namespace: molecular_function +def: "An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3." [GOC:txnOH-2018, PMID:11500378, PMID:28340337, PMID:28842442] +synonym: "core RNA polymerase I binding transcription factor activity" BROAD [] +synonym: "general RNA polymerase I transcription factor activity" EXACT [] +synonym: "RNA polymerase I transcription general initiation factor activity" EXACT [] +synonym: "transcription factor activity, core RNA polymerase I binding" BROAD [] +is_a: GO:0140223 ! general transcription initiation factor activity +relationship: part_of GO:0006360 ! transcription by RNA polymerase I +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14736 xsd:anyURI +created_by: krc +creation_date: 2011-08-12T04:13:30Z + +[Term] +id: GO:0001182 +name: promoter clearance from RNA polymerase I promoter +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors." [GOC:txnOH] +is_a: GO:0001109 ! promoter clearance during DNA-templated transcription +relationship: part_of GO:0006360 ! transcription by RNA polymerase I +created_by: krc +creation_date: 2011-08-15T03:49:28Z + +[Term] +id: GO:0001183 +name: transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I." [GOC:txnOH] +is_a: GO:0006362 ! transcription elongation from RNA polymerase I promoter +relationship: part_of GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +created_by: krc +creation_date: 2011-08-15T03:57:25Z + +[Term] +id: GO:0001184 +name: promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript +namespace: biological_process +def: "Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors." [GOC:txnOH] +is_a: GO:0001182 ! promoter clearance from RNA polymerase I promoter +relationship: part_of GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +created_by: krc +creation_date: 2011-08-15T04:03:52Z + +[Term] +id: GO:0001186 +name: obsolete RNA polymerase I transcription regulator recruiting activity +namespace: molecular_function +def: "OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation." [GOC:txnOH-2018, PMID:12381659, PMID:14969726, PMID:8057832] +comment: The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'. +synonym: "RNA polymerase I transcription factor recruiting activity" EXACT [] +synonym: "RNA polymerase I transcription factor recruiting transcription factor activity" EXACT [] +synonym: "transcription factor activity, RNA polymerase I transcription factor recruiting" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18561 xsd:anyURI +is_obsolete: true +replaced_by: GO:0003712 +created_by: krc +creation_date: 2011-08-24T04:00:18Z + +[Term] +id: GO:0001188 +name: RNA polymerase I preinitiation complex assembly +namespace: biological_process +alt_id: GO:0001189 +def: "The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter." [GOC:txnOH, PMID:12381659, PMID:14969726, PMID:8057832] +synonym: "RNA polymerase I transcriptional preinitiation complex assembly" EXACT [] +synonym: "RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript" NARROW [] +synonym: "RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript" NARROW [] +is_a: GO:0070897 ! transcription preinitiation complex assembly +relationship: part_of GO:0006361 ! transcription initiation from RNA polymerase I promoter +created_by: krc +creation_date: 2011-08-24T04:16:28Z + +[Term] +id: GO:0001190 +name: obsolete transcriptional activator activity, RNA polymerase II transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "RNA polymerase II transcription factor binding transcription activator activity" EXACT [] +synonym: "RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0001085 +consider: GO:0001228 +created_by: krc +creation_date: 2011-08-25T02:07:14Z + +[Term] +id: GO:0001191 +name: obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH, PMID:9811836] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription" EXACT [] +synonym: "RNA polymerase II transcription factor binding transcription repressor activity" EXACT [] +synonym: "RNA polymerase II transcription repressor activity" BROAD [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0001085 +consider: GO:0001227 +created_by: krc +creation_date: 2011-08-25T02:12:30Z + +[Term] +id: GO:0001192 +name: maintenance of transcriptional fidelity during DNA-templated transcription elongation +namespace: biological_process +def: "Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template." [GOC:txnOH] +synonym: "maintenance of transcriptional fidelity during DNA-dependent transcription elongation" EXACT [GOC:txnOH] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006354 ! DNA-templated transcription, elongation +created_by: krc +creation_date: 2011-09-02T02:25:30Z + +[Term] +id: GO:0001193 +name: maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter +namespace: biological_process +def: "Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter." [GOC:txnOH, PMID:14531857, PMID:16492753, PMID:17535246] +synonym: "maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter" EXACT [GOC:txnOH] +is_a: GO:0001192 ! maintenance of transcriptional fidelity during DNA-templated transcription elongation +relationship: part_of GO:0006368 ! transcription elongation from RNA polymerase II promoter +created_by: krc +creation_date: 2011-09-02T02:31:00Z + +[Term] +id: GO:0001194 +name: maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter +namespace: biological_process +def: "Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a bacterial-type RNA polymerase promoter." [GOC:txnOH] +synonym: "maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter" EXACT [GOC:txnOH] +is_a: GO:0001192 ! maintenance of transcriptional fidelity during DNA-templated transcription elongation +relationship: part_of GO:0001124 ! transcription elongation from bacterial-type RNA polymerase promoter +created_by: krc +creation_date: 2011-09-02T02:37:59Z + +[Term] +id: GO:0001195 +name: maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter +namespace: biological_process +def: "Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter." [GOC:txnOH] +synonym: "maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase III promoter" EXACT [GOC:txnOH] +is_a: GO:0001192 ! maintenance of transcriptional fidelity during DNA-templated transcription elongation +relationship: part_of GO:0006385 ! transcription elongation from RNA polymerase III promoter +created_by: krc +creation_date: 2011-09-02T02:41:29Z + +[Term] +id: GO:0001196 +name: regulation of mating-type specific transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:txnOH] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0007532 ! regulation of mating-type specific transcription, DNA-templated +intersection_of: GO:0007532 ! regulation of mating-type specific transcription, DNA-templated +intersection_of: regulates GO:0006366 ! transcription by RNA polymerase II +created_by: krc +creation_date: 2011-11-23T09:25:32Z + +[Term] +id: GO:0001197 +name: positive regulation of mating-type specific transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:txnOH] +synonym: "activation of transcription from an RNA polymerase II promoter, mating-type specific" NARROW [] +synonym: "stimulation of transcription from an RNA polymerase II promoter, mating-type specific" NARROW [] +synonym: "up regulation of transcription from an RNA polymerase II promoter, mating-type specific" EXACT [] +synonym: "up-regulation of transcription from an RNA polymerase II promoter, mating-type specific" EXACT [] +synonym: "upregulation of transcription from an RNA polymerase II promoter, mating-type specific" EXACT [] +is_a: GO:0001196 ! regulation of mating-type specific transcription from RNA polymerase II promoter +is_a: GO:0045895 ! positive regulation of mating-type specific transcription, DNA-templated +intersection_of: GO:0045895 ! positive regulation of mating-type specific transcription, DNA-templated +intersection_of: regulates GO:0006366 ! transcription by RNA polymerase II +created_by: krc +creation_date: 2011-11-23T09:31:33Z + +[Term] +id: GO:0001198 +name: negative regulation of mating-type specific transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:txnOH] +synonym: "down regulation of RNA polymerase II transcription, mating-type specific" EXACT [] +synonym: "down-regulation of RNA polymerase II transcription, mating-type specific" EXACT [] +synonym: "downregulation of RNA polymerase II transcription, mating-type specific" EXACT [] +synonym: "inhibition of RNA polymerase II transcription, mating-type specific" NARROW [] +is_a: GO:0001196 ! regulation of mating-type specific transcription from RNA polymerase II promoter +is_a: GO:0045894 ! negative regulation of mating-type specific transcription, DNA-templated +intersection_of: GO:0045894 ! negative regulation of mating-type specific transcription, DNA-templated +intersection_of: regulates GO:0006366 ! transcription by RNA polymerase II +created_by: krc +creation_date: 2011-11-23T09:36:06Z + +[Term] +id: GO:0001207 +name: histone displacement +namespace: biological_process +def: "The removal of histones, including histone dimers, from nucleosomes within chromatin." [GOC:krc, PMID:15525516, PMID:17496903, PMID:21807128] +is_a: GO:0034728 ! nucleosome organization +created_by: krc +creation_date: 2012-03-27T10:56:56Z + +[Term] +id: GO:0001208 +name: histone H2A-H2B dimer displacement +namespace: biological_process +def: "The removal of a H2A-H2B histone dimer from a nucleosome within chromatin." [GOC:krc, PMID:15525516, PMID:17496903, PMID:21807128] +is_a: GO:0001207 ! histone displacement +created_by: krc +creation_date: 2012-03-27T11:03:40Z + +[Term] +id: GO:0001216 +name: DNA-binding transcription activator activity +namespace: molecular_function +alt_id: GO:0001140 +alt_id: GO:0001215 +def: "Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase." [GOC:krc] +synonym: "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" RELATED [] +synonym: "bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding" NARROW [] +synonym: "transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding" RELATED [] +is_a: GO:0003700 ! DNA-binding transcription factor activity +relationship: part_of GO:0045893 ! positive regulation of transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16534 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16736 xsd:anyURI +created_by: krc +creation_date: 2011-01-26T03:09:27Z + +[Term] +id: GO:0001217 +name: DNA-binding transcription repressor activity +namespace: molecular_function +alt_id: GO:0001141 +alt_id: GO:0001218 +alt_id: GO:0001219 +alt_id: GO:0001220 +def: "Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase." [GOC:krc] +synonym: "bacterial-type DNA binding transcription repressor activity" NARROW [] +synonym: "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding" NARROW [] +synonym: "cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding" NARROW [] +synonym: "transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding" NARROW [] +is_a: GO:0003700 ! DNA-binding transcription factor activity +relationship: part_of GO:0045892 ! negative regulation of transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16736 xsd:anyURI +created_by: krc +creation_date: 2011-01-26T03:15:45Z + +[Term] +id: GO:0001221 +name: transcription cofactor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription cofactor, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery." [GOC:krc] +is_a: GO:0008134 ! transcription factor binding +created_by: krc +creation_date: 2012-04-16T03:19:05Z + +[Term] +id: GO:0001222 +name: transcription corepressor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery." [GOC:krc] +is_a: GO:0001221 ! transcription cofactor binding +created_by: krc +creation_date: 2012-04-16T03:27:26Z + +[Term] +id: GO:0001223 +name: transcription coactivator binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery." [GOC:krc] +is_a: GO:0001221 ! transcription cofactor binding +created_by: krc +creation_date: 2012-04-16T03:30:16Z + +[Term] +id: GO:0001224 +name: RNA polymerase II transcription cofactor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription cofactor for RNA polymerase II, any protein involved in regulation of transcription via protein-protein interactions with RNA polymerase II transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery of RNA polymerase II." [GOC:krc] +is_a: GO:0001221 ! transcription cofactor binding +created_by: krc +creation_date: 2012-04-16T03:37:06Z + +[Term] +id: GO:0001225 +name: RNA polymerase II transcription coactivator binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II." [GOC:krc] +is_a: GO:0001223 ! transcription coactivator binding +is_a: GO:0001224 ! RNA polymerase II transcription cofactor binding +created_by: krc +creation_date: 2012-04-16T03:39:41Z + +[Term] +id: GO:0001226 +name: RNA polymerase II transcription corepressor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase II transcription corepressor, any protein involved in negative regulation of transcription by RNA polymerase II via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery of RNA polymerase II." [GOC:krc] +is_a: GO:0001222 ! transcription corepressor binding +is_a: GO:0001224 ! RNA polymerase II transcription cofactor binding +created_by: krc +creation_date: 2012-04-16T03:39:47Z + +[Term] +id: GO:0001227 +name: DNA-binding transcription repressor activity, RNA polymerase II-specific +namespace: molecular_function +alt_id: GO:0001078 +alt_id: GO:0001206 +alt_id: GO:0001210 +alt_id: GO:0001214 +def: "A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units." [GOC:txnOH-2018] +synonym: "distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW [] +synonym: "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW [] +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" EXACT [] +synonym: "RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW [] +synonym: "RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW [] +synonym: "transcriptional repressor activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW [] +synonym: "transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT [] +is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific +is_a: GO:0001217 ! DNA-binding transcription repressor activity +relationship: part_of GO:0000122 ! negative regulation of transcription by RNA polymerase II +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16131 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16152 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16534 xsd:anyURI +created_by: krc +creation_date: 2010-10-26T03:56:48Z + +[Term] +id: GO:0001228 +name: DNA-binding transcription activator activity, RNA polymerase II-specific +namespace: molecular_function +alt_id: GO:0001077 +alt_id: GO:0001205 +alt_id: GO:0001209 +alt_id: GO:0001211 +alt_id: GO:0001212 +alt_id: GO:0001213 +def: "A protein, or a member of a complex, or a non-coding RNA that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units." [GOC:aruk, GOC:txnOH-2018, PMID:20737563, PMID:27145859] +synonym: "copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific" NARROW [] +synonym: "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific" NARROW [] +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription" EXACT [] +synonym: "RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW [] +synonym: "RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding" NARROW [] +synonym: "RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW [] +synonym: "transcriptional activator activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding" NARROW [] +synonym: "transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding" NARROW [] +synonym: "transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT [] +synonym: "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription" NARROW [] +is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific +is_a: GO:0001216 ! DNA-binding transcription activator activity +relationship: part_of GO:0045944 ! positive regulation of transcription by RNA polymerase II +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16131 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16152 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16534 xsd:anyURI +created_by: krc +creation_date: 2012-01-26T03:10:20Z + +[Term] +id: GO:0001300 +name: chronological cell aging +namespace: biological_process +def: "The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state." [GOC:jh, PMID:12044934] +synonym: "chronological cell ageing" EXACT [] +is_a: GO:0007569 ! cell aging + +[Term] +id: GO:0001301 +name: progressive alteration of chromatin involved in cell aging +namespace: biological_process +def: "Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype." [GOC:jh, GOC:vw, PMID:12044938] +synonym: "age-dependent accumulation of genetic damage" RELATED [] +synonym: "progressive alteration of chromatin during cell ageing" EXACT [] +synonym: "progressive alteration of chromatin during cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006325 ! chromatin organization +intersection_of: GO:0006325 ! chromatin organization +intersection_of: part_of GO:0007569 ! cell aging +relationship: part_of GO:0007569 ! cell aging + +[Term] +id: GO:0001302 +name: replicative cell aging +namespace: biological_process +def: "The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division." [GOC:jh, PMID:12044934] +synonym: "replicative cell ageing" EXACT [] +is_a: GO:0007569 ! cell aging + +[Term] +id: GO:0001303 +name: nucleolar fragmentation involved in replicative aging +namespace: biological_process +def: "A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells." [GOC:jh, PMID:9891807] +synonym: "nucleolar fragmentation during replicative ageing" RELATED [] +synonym: "nucleolar fragmentation during replicative aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007576 ! nucleolar fragmentation +intersection_of: GO:0007576 ! nucleolar fragmentation +intersection_of: part_of GO:0001302 ! replicative cell aging +relationship: part_of GO:0001302 ! replicative cell aging + +[Term] +id: GO:0001304 +name: progressive alteration of chromatin involved in replicative cell aging +namespace: biological_process +def: "A process that results in changes in chromatin structure contributing to replicative cell aging." [GOC:dph, GOC:jh, GOC:tb] +synonym: "progressive alteration of chromatin during replicative cell ageing" EXACT [] +synonym: "progressive alteration of chromatin during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001301 ! progressive alteration of chromatin involved in cell aging +intersection_of: GO:0001301 ! progressive alteration of chromatin involved in cell aging +intersection_of: part_of GO:0001302 ! replicative cell aging +relationship: part_of GO:0001302 ! replicative cell aging + +[Term] +id: GO:0001305 +name: progressive alteration of chromatin involved in chronological cell aging +namespace: biological_process +def: "A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells." [GOC:dph, GOC:jh, GOC:tb] +synonym: "progressive alteration of chromatin during chronological cell ageing" RELATED [] +synonym: "progressive alteration of chromatin during chronological cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001301 ! progressive alteration of chromatin involved in cell aging +intersection_of: GO:0001301 ! progressive alteration of chromatin involved in cell aging +intersection_of: part_of GO:0001300 ! chronological cell aging +relationship: part_of GO:0001300 ! chronological cell aging + +[Term] +id: GO:0001306 +name: age-dependent response to oxidative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism." [GOC:jh, PMID:12044938] +is_a: GO:0006979 ! response to oxidative stress +relationship: part_of GO:0007571 ! age-dependent general metabolic decline + +[Term] +id: GO:0001307 +name: extrachromosomal circular DNA accumulation involved in replicative cell aging +namespace: biological_process +def: "Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication." [GOC:jh] +synonym: "extrachromosomal circular DNA accumulation during replicative cell ageing" RELATED [] +synonym: "extrachromosomal circular DNA accumulation during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001304 ! progressive alteration of chromatin involved in replicative cell aging +is_a: GO:0007580 ! extrachromosomal circular DNA accumulation involved in cell aging + +[Term] +id: GO:0001308 +name: negative regulation of chromatin silencing involved in replicative cell aging +namespace: biological_process +def: "The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins." [GOC:jh, PMID:12044934] +synonym: "loss of chromatin silencing during replicative cell ageing" RELATED [] +synonym: "loss of chromatin silencing involved in replicative cell aging" EXACT [] +is_a: GO:0001304 ! progressive alteration of chromatin involved in replicative cell aging +is_a: GO:0031936 ! negative regulation of chromatin silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006342 ! chromatin silencing +intersection_of: part_of GO:0001302 ! replicative cell aging + +[Term] +id: GO:0001309 +name: obsolete age-dependent telomere shortening +namespace: biological_process +def: "OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process." [GOC:jh, PMID:9891807] +comment: This term was made obsolete because it represents a phenotype. +synonym: "age-dependent telomere shortening" EXACT [] +is_obsolete: true +consider: GO:1903824 + +[Term] +id: GO:0001310 +name: extrachromosomal rDNA circle accumulation involved in replicative cell aging +namespace: biological_process +def: "Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication." [GOC:jh, PMID:12044934] +synonym: "extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [] +synonym: "extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:dph, GOC:tb] +synonym: "extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [] +is_a: GO:0001307 ! extrachromosomal circular DNA accumulation involved in replicative cell aging + +[Term] +id: GO:0001311 +name: formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging +namespace: biological_process +def: "Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age." [GOC:jh, PMID:12044934] +synonym: "assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging" RELATED [] +synonym: "formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing" RELATED [] +synonym: "formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging" RELATED [GOC:dph, GOC:tb] +synonym: "formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging" RELATED [] +is_a: GO:0001313 ! formation of extrachromosomal circular DNA involved in replicative cell aging +is_a: GO:0045458 ! recombination within rDNA repeats +relationship: part_of GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging + +[Term] +id: GO:0001312 +name: replication of extrachromosomal rDNA circles involved in replicative cell aging +namespace: biological_process +def: "Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication." [GOC:jh, PMID:12044934] +synonym: "replication of extrachromosomal rDNA circles during replicative cell ageing" RELATED [] +synonym: "replication of extrachromosomal rDNA circles during replicative cell aging" RELATED [GOC:dph, GOC:tb] +synonym: "replication of extrachromosomal ribosomal DNA circles during replicative cell aging" RELATED [] +is_a: GO:0001314 ! replication of extrachromosomal circular DNA involved in replicative cell aging +relationship: part_of GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging + +[Term] +id: GO:0001313 +name: formation of extrachromosomal circular DNA involved in replicative cell aging +namespace: biological_process +def: "Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age." [GOC:jh] +synonym: "assembly of extrachromosomal circular DNA involved in replicative cell aging" EXACT [] +synonym: "formation of extrachromosomal circular DNA during replicative cell ageing" RELATED [] +synonym: "formation of extrachromosomal circular DNA during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001325 ! formation of extrachromosomal circular DNA +intersection_of: GO:0001325 ! formation of extrachromosomal circular DNA +intersection_of: part_of GO:0001302 ! replicative cell aging +relationship: part_of GO:0001307 ! extrachromosomal circular DNA accumulation involved in replicative cell aging + +[Term] +id: GO:0001314 +name: replication of extrachromosomal circular DNA involved in replicative cell aging +namespace: biological_process +def: "Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication." [GOC:jh] +synonym: "replication of extrachromosomal circular DNA during replicative cell ageing" EXACT [] +synonym: "replication of extrachromosomal circular DNA during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001326 ! replication of extrachromosomal circular DNA +intersection_of: GO:0001326 ! replication of extrachromosomal circular DNA +intersection_of: part_of GO:0001302 ! replicative cell aging +relationship: part_of GO:0001307 ! extrachromosomal circular DNA accumulation involved in replicative cell aging + +[Term] +id: GO:0001315 +name: age-dependent response to reactive oxygen species +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism." [GOC:jh, PMID:12044938] +synonym: "age-dependent response to active oxygen species" EXACT [] +synonym: "age-dependent response to AOS" EXACT [] +synonym: "age-dependent response to reactive oxidative species" EXACT [] +synonym: "age-dependent response to reactive oxygen intermediate" EXACT [] +synonym: "age-dependent response to ROI" EXACT [] +synonym: "age-dependent response to ROS" EXACT [] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0001306 ! age-dependent response to oxidative stress + +[Term] +id: GO:0001316 +name: age-dependent response to reactive oxygen species involved in replicative cell aging +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism." [GOC:jh] +synonym: "age-dependent response to active oxygen species during replicative cell aging" RELATED [] +synonym: "age-dependent response to AOS during replicative cell aging" EXACT [] +synonym: "age-dependent response to reactive oxidative species during replicative cell aging" EXACT [] +synonym: "age-dependent response to reactive oxygen intermediate during replicative cell aging" RELATED [] +synonym: "age-dependent response to reactive oxygen species during replicative cell ageing" EXACT [] +synonym: "age-dependent response to reactive oxygen species during replicative cell aging" RELATED [GOC:dph, GOC:tb] +synonym: "age-dependent response to ROI during replicative cell aging" RELATED [] +synonym: "age-dependent response to ROS during replicative cell aging" RELATED [] +is_a: GO:0001322 ! age-dependent response to oxidative stress involved in replicative cell aging +is_a: GO:0072353 ! cellular age-dependent response to reactive oxygen species + +[Term] +id: GO:0001317 +name: accumulation of oxidatively modified proteins involved in replicative cell aging +namespace: biological_process +def: "Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking." [GOC:jh] +synonym: "accumulation of oxidatively modified proteins during replicative cell ageing" RELATED [] +synonym: "accumulation of oxidatively modified proteins during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001316 ! age-dependent response to reactive oxygen species involved in replicative cell aging + +[Term] +id: GO:0001318 +name: formation of oxidatively modified proteins involved in replicative cell aging +namespace: biological_process +def: "Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking." [GOC:jh] +synonym: "formation of oxidatively modified proteins during replicative cell ageing" RELATED [] +synonym: "formation of oxidatively modified proteins during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006464 ! cellular protein modification process +relationship: part_of GO:0001317 ! accumulation of oxidatively modified proteins involved in replicative cell aging + +[Term] +id: GO:0001319 +name: inheritance of oxidatively modified proteins involved in replicative cell aging +namespace: biological_process +def: "A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells." [GOC:jh] +synonym: "inheritance of oxidatively modified proteins during replicative cell ageing" RELATED [] +synonym: "inheritance of oxidatively modified proteins during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0008104 ! protein localization +relationship: part_of GO:0001317 ! accumulation of oxidatively modified proteins involved in replicative cell aging + +[Term] +id: GO:0001320 +name: age-dependent response to reactive oxygen species involved in chronological cell aging +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism." [GOC:jh] +synonym: "age-dependent response to active oxygen species during chronological cell aging" RELATED [] +synonym: "age-dependent response to AOS during chronological cell aging" RELATED [] +synonym: "age-dependent response to reactive oxidative species during chronological cell aging" RELATED [] +synonym: "age-dependent response to reactive oxygen intermediate during chronological cell aging" RELATED [] +synonym: "age-dependent response to reactive oxygen species during chronological cell ageing" RELATED [] +synonym: "age-dependent response to reactive oxygen species during chronological cell aging" RELATED [GOC:dph, GOC:tb] +synonym: "age-dependent response to ROI during chronological cell aging" RELATED [] +synonym: "age-dependent response to ROS during chronological cell aging" RELATED [] +is_a: GO:0001324 ! age-dependent response to oxidative stress involved in chronological cell aging +is_a: GO:0072353 ! cellular age-dependent response to reactive oxygen species +intersection_of: GO:0001315 ! age-dependent response to reactive oxygen species +intersection_of: part_of GO:0001300 ! chronological cell aging + +[Term] +id: GO:0001321 +name: age-dependent general metabolic decline involved in replicative cell aging +namespace: biological_process +def: "A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function." [GOC:jh, GOC:mah] +synonym: "age-dependent general metabolic decline during replicative cell ageing" RELATED [] +synonym: "age-dependent general metabolic decline involved in replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007571 ! age-dependent general metabolic decline +intersection_of: GO:0007571 ! age-dependent general metabolic decline +intersection_of: part_of GO:0001302 ! replicative cell aging +relationship: part_of GO:0001302 ! replicative cell aging + +[Term] +id: GO:0001322 +name: age-dependent response to oxidative stress involved in replicative cell aging +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism." [GOC:jh] +synonym: "age-dependent response to oxidative stress during replicative cell ageing" RELATED [] +synonym: "age-dependent response to oxidative stress during replicative cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001306 ! age-dependent response to oxidative stress +intersection_of: GO:0001306 ! age-dependent response to oxidative stress +intersection_of: part_of GO:0001321 ! age-dependent general metabolic decline involved in replicative cell aging +relationship: part_of GO:0001321 ! age-dependent general metabolic decline involved in replicative cell aging +relationship: part_of GO:0034599 ! cellular response to oxidative stress + +[Term] +id: GO:0001323 +name: age-dependent general metabolic decline involved in chronological cell aging +namespace: biological_process +def: "A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function." [GOC:jh, GOC:mah] +synonym: "age-dependent general metabolic decline during chronological cell ageing" RELATED [] +synonym: "age-dependent general metabolic decline during chronological cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007571 ! age-dependent general metabolic decline +intersection_of: GO:0007571 ! age-dependent general metabolic decline +intersection_of: part_of GO:0001300 ! chronological cell aging +relationship: part_of GO:0001300 ! chronological cell aging + +[Term] +id: GO:0001324 +name: age-dependent response to oxidative stress involved in chronological cell aging +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism." [GOC:jh] +synonym: "age-dependent response to oxidative stress during chronological cell ageing" RELATED [] +synonym: "age-dependent response to oxidative stress during chronological cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001306 ! age-dependent response to oxidative stress +is_a: GO:0034599 ! cellular response to oxidative stress +intersection_of: GO:0001306 ! age-dependent response to oxidative stress +intersection_of: part_of GO:0001300 ! chronological cell aging +relationship: part_of GO:0001323 ! age-dependent general metabolic decline involved in chronological cell aging + +[Term] +id: GO:0001325 +name: formation of extrachromosomal circular DNA +namespace: biological_process +def: "Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats." [GOC:jh, PMID:12044938] +synonym: "assembly of extrachromosomal circular DNA" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0022607 ! cellular component assembly + +[Term] +id: GO:0001326 +name: replication of extrachromosomal circular DNA +namespace: biological_process +def: "Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication." [GOC:jh] +is_a: GO:0006260 ! DNA replication + +[Term] +id: GO:0001400 +name: mating projection base +namespace: cellular_component +def: "The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone." [GOC:mcc] +synonym: "base of shmoo tip" NARROW [] +synonym: "conjugation tube base" NARROW [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005937 ! mating projection + +[Term] +id: GO:0001401 +name: SAM complex +namespace: cellular_component +def: "A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex." [PMID:12891361] +comment: See also the cellular component term 'mitochondrial outer membrane translocase complex ; GO:0005742'. +synonym: "mitochondrial sorting and assembly machinery complex" EXACT [] +synonym: "TOB complex" EXACT [] +is_a: GO:0098799 ! outer mitochondrial membrane protein complex + +[Term] +id: GO:0001402 +name: signal transduction involved in filamentous growth +namespace: biological_process +def: "Relaying of environmental signals promoting filamentous growth." [GOC:mcc, PMID:9728395] +synonym: "MAPKKK cascade (pseudohyphal growth)" RELATED [] +synonym: "signal transduction during filamentous growth" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0030447 ! filamentous growth +relationship: part_of GO:0030447 ! filamentous growth + +[Term] +id: GO:0001403 +name: invasive growth in response to glucose limitation +namespace: biological_process +def: "A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae." [GOC:mcc, PMID:9728395] +comment: Note that this term should not be used to describe the invasion of host tissues by pathogenic organisms, which is described by the biological process term 'entry into host ; GO:0044409', nor should it be used to describe growth of diseased cells of an organism into the surrounding normal tissue, which is outside of the scope of GO. +subset: goslim_yeast +synonym: "colony morphology" RELATED [] +is_a: GO:0036267 ! invasive filamentous growth + +[Term] +id: GO:0001404 +name: obsolete invasive growth +namespace: biological_process +def: "OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue." [GOC:mcc, PMID:9728395] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "invasive growth" EXACT [] +synonym: "tissue invasion" EXACT [] +is_obsolete: true +consider: GO:0044409 + +[Term] +id: GO:0001405 +name: PAM complex, Tim23 associated import motor +namespace: cellular_component +def: "Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix." [GOC:mcc, GOC:vw, PMID:14517234, PMID:14638855] +synonym: "mitochondrial import motor" EXACT [] +synonym: "PAM complex" EXACT [] +synonym: "pre-sequence translocase-associated import motor" EXACT [] +synonym: "presequence translocase-associated import motor" EXACT [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +relationship: part_of GO:0005744 ! TIM23 mitochondrial import inner membrane translocase complex +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0001406 +name: glycerophosphodiester transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol." [GOC:mcc, PMID:12912892] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +relationship: part_of GO:0001407 ! glycerophosphodiester transmembrane transport + +[Term] +id: GO:0001407 +name: glycerophosphodiester transmembrane transport +namespace: biological_process +def: "The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol." [GOC:mcc, PMID:12912892] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0001408 +name: guanine nucleotide transport +namespace: biological_process +def: "The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mcc] +is_a: GO:0015865 ! purine nucleotide transport + +[Term] +id: GO:0001409 +name: guanine nucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other." [GOC:mcc] +is_a: GO:0015216 ! purine nucleotide transmembrane transporter activity +relationship: part_of GO:1903790 ! guanine nucleotide transmembrane transport + +[Term] +id: GO:0001410 +name: chlamydospore formation +namespace: biological_process +alt_id: GO:0055027 +def: "The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans." [GOC:mcc, GOC:mtg_sensu, ISBN:085199377X, PMID:14663094] +synonym: "chlamydospore development" EXACT [] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore +is_a: GO:0048468 ! cell development + +[Term] +id: GO:0001411 +name: hyphal tip +namespace: cellular_component +def: "The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation." [GOC:mcc] +subset: goslim_candida +is_a: GO:0030427 ! site of polarized growth +is_a: GO:0051286 ! cell tip + +[Term] +id: GO:0001501 +name: skeletal system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb] +synonym: "skeletal development" EXACT [] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0001502 +name: cartilage condensation +namespace: biological_process +def: "The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes." [ISBN:0878932437] +is_a: GO:0098743 ! cell aggregation +relationship: part_of GO:0048705 ! skeletal system morphogenesis +relationship: part_of GO:0051216 ! cartilage development + +[Term] +id: GO:0001503 +name: ossification +namespace: biological_process +def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649] +comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'. +synonym: "bone biosynthesis" EXACT [] +synonym: "bone formation" EXACT [] +synonym: "osteogenesis" EXACT [] +xref: Wikipedia:Ossification +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0001504 +name: neurotransmitter uptake +namespace: biological_process +def: "The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters." [ISBN:0123668387] +subset: goslim_synapse +synonym: "neurotransmitter import" EXACT [GOC:dph, GOC:tb] +synonym: "neurotransmitter import into glial cell" NARROW [] +synonym: "neurotransmitter import into neuron" NARROW [] +synonym: "neurotransmitter recycling" BROAD [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0098657 ! import into cell + +[Term] +id: GO:0001505 +name: regulation of neurotransmitter levels +namespace: biological_process +def: "Any process that modulates levels of neurotransmitter." [GOC:jl] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0001506 +name: obsolete neurotransmitter biosynthetic process and storage +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules." [GOC:go_curators, ISBN:0123668387] +comment: This term was made obsolete because it is an amalgamation of its two children. +synonym: "neurotransmitter anabolism and storage" EXACT [] +synonym: "neurotransmitter biosynthetic process and storage" EXACT [] +synonym: "neurotransmitter formation and storage" EXACT [] +synonym: "neurotransmitter synthesis and storage" EXACT [] +is_obsolete: true +consider: GO:0042136 +consider: GO:0042137 + +[Term] +id: GO:0001507 +name: acetylcholine catabolic process in synaptic cleft +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission." [GOC:ai] +synonym: "acetylcholine breakdown in synaptic cleft" EXACT [] +synonym: "acetylcholine degradation in synaptic cleft" EXACT [] +is_a: GO:0006581 ! acetylcholine catabolic process +intersection_of: GO:0006581 ! acetylcholine catabolic process +intersection_of: occurs_in GO:0043083 ! synaptic cleft +relationship: occurs_in GO:0043083 ! synaptic cleft +relationship: part_of GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0001508 +name: action potential +namespace: biological_process +def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] +comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so. +is_a: GO:0042391 ! regulation of membrane potential +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0001509 +name: obsolete legumain activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds." [EC:3.4.22.34] +comment: This term was made obsolete because it represents a gene product. +synonym: "asparaginyl endopeptidase activity" RELATED [EC:3.4.22.34] +synonym: "bean endopeptidase activity" RELATED [EC:3.4.22.34] +synonym: "citvac" RELATED [EC:3.4.22.34] +synonym: "hemoglobinase activity" RELATED [EC:3.4.22.34] +synonym: "legumain activity" EXACT [] +synonym: "phaseolin activity" RELATED [EC:3.4.22.34] +synonym: "proteinase B" RELATED [EC:3.4.22.34] +synonym: "PRSC1 gene product (Homo sapiens)" RELATED [EC:3.4.22.34] +synonym: "vicilin peptidohydrolase activity" RELATED [EC:3.4.22.34] +xref: EC:3.4.22.34 +xref: MetaCyc:3.4.22.34-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0001510 +name: RNA methylation +namespace: biological_process +def: "Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor." [GOC:hjd] +is_a: GO:0009451 ! RNA modification +is_a: GO:0043414 ! macromolecule methylation + +[Term] +id: GO:0001511 +name: obsolete fibrillin +namespace: molecular_function +def: "OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "fibrillin" EXACT [] +is_obsolete: true +consider: GO:0001527 +consider: GO:0005509 + +[Term] +id: GO:0001512 +name: dihydronicotinamide riboside quinone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone." [EC:1.10.99.2] +synonym: "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity" EXACT [EC:1.10.99.2] +synonym: "N-ribosyldihydronicotinamide dehydrogenase (quinone) activity" EXACT [EC:1.10.99.2] +synonym: "NAD(P)H:quinone oxidoreductase 2 activity" EXACT [EC:1.10.99.2] +synonym: "NAD(P)H:quinone oxidoreductase-2" RELATED [EC:1.10.99.2] +synonym: "NAD(P)H:quinone oxidoreductase2" RELATED [EC:1.10.99.2] +synonym: "NQO(2) activity" EXACT [EC:1.10.99.2] +synonym: "NQO2" RELATED [EC:1.10.99.2] +synonym: "NRH:quinone oxidoreductase 2 activity" NARROW [EC:1.10.99.2] +synonym: "QR2 activity" RELATED [EC:1.10.99.2] +synonym: "quinone reductase 2 activity" RELATED [EC:1.10.99.2] +synonym: "ribosyldihydronicotinamide dehydrogenase (quinone) activity" EXACT [] +xref: EC:1.10.99.2 +xref: MetaCyc:1.10.99.2-RXN +xref: Reactome:R-HSA-8936519 "NQO2:FAD dimer reduces quinones to hydroquinones" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0001514 +name: selenocysteine incorporation +namespace: biological_process +def: "The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine." [RESID:AA0022] +xref: RESID:AA0022 +is_a: GO:0006451 ! translational readthrough + +[Term] +id: GO:0001515 +name: opioid peptide activity +namespace: molecular_function +def: "Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect." [ISBN:0198506732] +subset: goslim_chembl +is_a: GO:0048018 ! receptor ligand activity + +[Term] +id: GO:0001516 +name: prostaglandin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring." [GOC:ai] +synonym: "prostaglandin anabolism" EXACT [] +synonym: "prostaglandin biosynthesis" EXACT [] +synonym: "prostaglandin formation" EXACT [] +synonym: "prostaglandin synthesis" EXACT [] +is_a: GO:0006693 ! prostaglandin metabolic process +is_a: GO:0046457 ! prostanoid biosynthetic process + +[Term] +id: GO:0001517 +name: N-acetylglucosamine 6-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate." [GOC:ai, GOC:hjd] +subset: goslim_chembl +synonym: "N-acetylglucosamine 6-O-sulphotransferase activity" EXACT [] +xref: Reactome:R-HSA-2046222 "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG" +xref: Reactome:R-HSA-3656269 "Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG" +xref: Reactome:R-HSA-6786012 "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0001518 +name: voltage-gated sodium channel complex +namespace: cellular_component +def: "A sodium channel in a cell membrane whose opening is governed by the membrane potential." [ISBN:0198506732] +synonym: "voltage gated sodium channel complex" EXACT [] +synonym: "voltage-dependent sodium channel complex" EXACT [] +synonym: "voltage-sensitive sodium channel complex" EXACT [] +xref: NIF_Subcellular:sao785001660 +is_a: GO:0034706 ! sodium channel complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0001519 +name: peptide amidation +namespace: biological_process +def: "The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions." [PMID:11028916] +is_a: GO:0031179 ! peptide modification + +[Term] +id: GO:0001520 +name: outer dense fiber +namespace: cellular_component +def: "A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins." [GOC:cilia, GOC:krc, ISBN:0824072820, PMID:10381817, PMID:21586547, PMID:25361759] +synonym: "outer dense fibre" EXACT [] +is_a: GO:0099513 ! polymeric cytoskeletal fiber +relationship: part_of GO:0036126 ! sperm flagellum + +[Term] +id: GO:0001522 +name: pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs." [GOC:hjd, GOC:mah] +synonym: "pseudouridylation" EXACT [] +xref: Wikipedia:Pseudouridine +xref: Wikipedia:Pseudouridylation +is_a: GO:0009451 ! RNA modification + +[Term] +id: GO:0001523 +name: retinoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity." [ISBN:0198506732] +synonym: "retinoid metabolism" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process + +[Term] +id: GO:0001524 +name: obsolete globin +namespace: molecular_function +def: "OBSOLETE. The colorless and basic protein moiety of hemoglobin and myoglobins." [GOC:ai, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "globin" EXACT [] +is_obsolete: true +replaced_by: GO:0005344 + +[Term] +id: GO:0001525 +name: angiogenesis +namespace: biological_process +def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453] +synonym: "blood vessel formation from pre-existing blood vessels" EXACT systematic_synonym [] +xref: Wikipedia:Angiogenesis +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048514 ! blood vessel morphogenesis + +[Term] +id: GO:0001526 +name: obsolete proteoglycan sulfate transfer +namespace: biological_process +def: "OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate." [GOC:hjd] +comment: This term was made obsolete because it represents a group of molecular functions. +synonym: "proteoglycan sulfate transfer" EXACT [] +synonym: "proteoglycan sulphate transfer" EXACT [] +is_obsolete: true +consider: GO:0006029 +consider: GO:0006790 +consider: GO:0050698 + +[Term] +id: GO:0001527 +name: microfibril +namespace: cellular_component +def: "Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins." [PMID:27026396] +synonym: "extended fibrils" EXACT [] +synonym: "fibrillin" RELATED [] +is_a: GO:0099512 ! supramolecular fiber +relationship: part_of GO:0031012 ! extracellular matrix + +[Term] +id: GO:0001528 +name: obsolete elastin +namespace: molecular_function +def: "OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "elastin" EXACT [] +is_obsolete: true +replaced_by: GO:0030023 + +[Term] +id: GO:0001529 +name: obsolete elastin +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "elastin" EXACT [] +is_obsolete: true +replaced_by: GO:0030023 + +[Term] +id: GO:0001530 +name: lipopolysaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipopolysaccharide." [PMID:11079463] +synonym: "endotoxin binding" BROAD [] +synonym: "LPS binding" EXACT [] +is_a: GO:0008289 ! lipid binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0001531 +name: interleukin-21 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-21 receptor." [GOC:ai] +synonym: "IL-21" NARROW [] +synonym: "interleukin-21 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0001532 +name: interleukin-21 receptor activity +namespace: molecular_function +def: "Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-21 receptor activity" EXACT [GOC:mah] +synonym: "IL-21R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019977 ! interleukin-21 binding +relationship: part_of GO:0038114 ! interleukin-21-mediated signaling pathway + +[Term] +id: GO:0001533 +name: cornified envelope +namespace: cellular_component +def: "A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes)." [GOC:add, PMID:11112355, PMID:11590230, PMID:15803139] +is_a: GO:0005886 ! plasma membrane +property_value: RO:0002161 NCBITaxon:50557 + +[Term] +id: GO:0001534 +name: radial spoke +namespace: cellular_component +def: "Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules." [ISBN:0124325653, PMID:9450971] +subset: goslim_pir +xref: Wikipedia:Radial_spoke +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005930 ! axoneme + +[Term] +id: GO:0001535 +name: radial spoke head +namespace: cellular_component +def: "Protein complex forming part of eukaryotic flagellar apparatus." [GOC:cilia, GOC:hjd, GOC:krc] +synonym: "radial spokehead" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0001534 ! radial spoke + +[Term] +id: GO:0001536 +name: radial spoke stalk +namespace: cellular_component +def: "Globular portion of the radial spoke that projects towards the central pair of microtubules." [GOC:hjd] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0001534 ! radial spoke + +[Term] +id: GO:0001537 +name: N-acetylgalactosamine 4-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate." [EC:2.8.2.-, GOC:ai] +synonym: "N-acetylgalactosamine 4-O-sulphotransferase activity" EXACT [] +xref: Reactome:R-HSA-2022063 "CHST14 transfers SO4(2-) to GalNAc in dermatan or DS" +xref: Reactome:R-HSA-3636919 "Defective CHST14 does not transfer SO4(2-) to GalNAc in dermatan or DS" +xref: Reactome:R-HSA-6786034 "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0001539 +name: cilium or flagellum-dependent cell motility +namespace: biological_process +def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc] +comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "ciliary or bacterial-type flagellar motility" RELATED [] +synonym: "ciliary/flagellar motility" EXACT [] +is_a: GO:0048870 ! cell motility + +[Term] +id: GO:0001540 +name: amyloid-beta binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor." [GOC:hjd] +subset: goslim_chembl +synonym: "beta-amyloid binding" EXACT [] +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0001541 +name: ovarian follicle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure." [GOC:go_curators] +synonym: "follicular phase" RELATED [] +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0008585 ! female gonad development + +[Term] +id: GO:0001542 +name: ovulation from ovarian follicle +namespace: biological_process +def: "The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus." [GOC:mtg_sensu, http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0030728 ! ovulation +relationship: part_of GO:0008585 ! female gonad development + +[Term] +id: GO:0001543 +name: ovarian follicle rupture +namespace: biological_process +def: "Disruption of theca cell layer releasing follicular fluid and/or the oocyte." [http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0001542 ! ovulation from ovarian follicle + +[Term] +id: GO:0001544 +name: initiation of primordial ovarian follicle growth +namespace: biological_process +def: "Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle)." [http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0001541 ! ovarian follicle development + +[Term] +id: GO:0001545 +name: primary ovarian follicle growth +namespace: biological_process +def: "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle)." [GOC:mtg_mpo, http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0040007 ! growth +relationship: part_of GO:0001541 ! ovarian follicle development + +[Term] +id: GO:0001546 +name: preantral ovarian follicle growth +namespace: biological_process +def: "Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation." [http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0040007 ! growth +relationship: part_of GO:0001541 ! ovarian follicle development +relationship: part_of GO:0048162 ! multi-layer follicle stage + +[Term] +id: GO:0001547 +name: antral ovarian follicle growth +namespace: biological_process +def: "Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity." [http://ovary.stanford.edu] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0001541 ! ovarian follicle development + +[Term] +id: GO:0001548 +name: follicular fluid formation in ovarian follicle antrum +namespace: biological_process +def: "The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis." [GOC:dph, GOC:tb, http://ovary.stanford.edu] +synonym: "ovarian follicle antrum/follicular fluid biosynthesis" EXACT [] +synonym: "ovarian follicle antrum/follicular fluid formation" EXACT [] +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0001547 ! antral ovarian follicle growth + +[Term] +id: GO:0001549 +name: cumulus cell differentiation +namespace: biological_process +def: "The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell." [http://ovary.stanford.edu] +synonym: "ovarian cumulus cell differentiation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0001547 ! antral ovarian follicle growth +relationship: part_of GO:0048165 ! fused antrum stage + +[Term] +id: GO:0001550 +name: ovarian cumulus expansion +namespace: biological_process +def: "Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells." [http://ovary.stanford.edu] +synonym: "ovarian cumulus growth" RELATED [] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0040007 ! growth +relationship: part_of GO:0001547 ! antral ovarian follicle growth +relationship: part_of GO:0048165 ! fused antrum stage + +[Term] +id: GO:0001551 +name: ovarian follicle endowment +namespace: biological_process +def: "Association of oocytes with supporting epithelial granulosa cells to form primordial follicles." [http://ovary.stanford.edu] +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0001541 ! ovarian follicle development + +[Term] +id: GO:0001552 +name: ovarian follicle atresia +namespace: biological_process +def: "A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed." [GOC:mtg_apoptosis, PMID:18638134] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: has_part GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: part_of GO:0008585 ! female gonad development + +[Term] +id: GO:0001553 +name: luteinization +namespace: biological_process +def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [http://ovary.stanford.edu] +synonym: "luteal phase" RELATED [] +xref: Wikipedia:Luteal_phase +xref: Wikipedia:Luteinization +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0008585 ! female gonad development + +[Term] +id: GO:0001554 +name: luteolysis +namespace: biological_process +def: "The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy." [PMID:10617764] +xref: Wikipedia:Luteolysis +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0008585 ! female gonad development + +[Term] +id: GO:0001555 +name: oocyte growth +namespace: biological_process +def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [http://ovary.stanford.edu] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0048599 ! oocyte development + +[Term] +id: GO:0001556 +name: oocyte maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, http://ovary.stanford.edu] +xref: Wikipedia:Oocyte_maturation +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0048599 ! oocyte development + +[Term] +id: GO:0001557 +name: obsolete metabolic process resulting in cell growth +namespace: biological_process +def: "OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell." [GOC:dph] +comment: This term was made obsolete as part of the metabolism rearrangements, because it is redundant with other terms. +synonym: "metabolic process resulting in cell growth" EXACT [] +is_obsolete: true +consider: GO:0008152 +consider: GO:0016049 + +[Term] +id: GO:0001558 +name: regulation of cell growth +namespace: biological_process +def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators] +is_a: GO:0040008 ! regulation of growth +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016049 ! cell growth +relationship: regulates GO:0016049 ! cell growth + +[Term] +id: GO:0001559 +name: regulation of cell growth by detection of nuclear:cytoplasmic ratio +namespace: biological_process +def: "Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." [GOC:dph] +synonym: "detection of nuclear:cytoplasmic ratio to regulate cell growth" EXACT [] +synonym: "interpretation of nuclear:cytoplasmic ratio to regulate cell growth" EXACT [] +synonym: "regulation of cell growth by nuclear:cytoplasmic ratio" EXACT [] +synonym: "regulation of cell growth by sensing of nuclear:cytoplasmic ratio" EXACT [] +is_a: GO:0016475 ! detection of nuclear:cytoplasmic ratio +is_a: GO:0061387 ! regulation of extent of cell growth +intersection_of: GO:0016475 ! detection of nuclear:cytoplasmic ratio +intersection_of: regulates GO:0016049 ! cell growth + +[Term] +id: GO:0001560 +name: regulation of cell growth by extracellular stimulus +namespace: biological_process +def: "Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." [GOC:dph] +synonym: "interpretation of external signals that regulate cell growth" EXACT [] +synonym: "regulation of cell growth by detection of exogenous stimulus" EXACT [] +synonym: "regulation of cell growth by sensing of exogenous stimulus" EXACT [] +synonym: "regulation of growth by exogenous signal" EXACT [] +synonym: "regulation of growth by exogenous stimuli" EXACT [] +synonym: "regulation of growth by exogenous stimulus" EXACT [] +synonym: "regulation of growth by external signal" EXACT [] +synonym: "regulation of growth by external stimuli" EXACT [] +synonym: "regulation of growth by external stimulus" EXACT [] +is_a: GO:0001558 ! regulation of cell growth +intersection_of: GO:0001558 ! regulation of cell growth +intersection_of: part_of GO:0031668 ! cellular response to extracellular stimulus +relationship: part_of GO:0031668 ! cellular response to extracellular stimulus + +[Term] +id: GO:0001561 +name: fatty acid alpha-oxidation +namespace: biological_process +def: "A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway." [http://www.peroxisome.org/Scientist/Biochemistry/alpha-oxidation.html] +xref: MetaCyc:PWY-2501 +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0001562 +name: response to protozoan +namespace: biological_process +alt_id: GO:0042833 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan." [GOC:ai] +synonym: "resistance to pathogenic protozoa" RELATED [] +synonym: "response to protozoa" EXACT [] +synonym: "response to protozoon" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0001563 +name: detection of protozoan +namespace: biological_process +def: "The series of events in which a stimulus from a protozoan is received and converted into a molecular signal." [GOC:ai] +synonym: "detection of protozoa" EXACT [] +synonym: "detection of protozoon" EXACT [] +synonym: "perception of protozoa" RELATED [] +is_a: GO:0001562 ! response to protozoan +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0001564 +name: obsolete resistance to pathogenic protozoa +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "resistance to pathogenic protozoa" EXACT [] +is_obsolete: true +replaced_by: GO:0001562 + +[Term] +id: GO:0001565 +name: phorbol ester receptor activity +namespace: molecular_function +def: "Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity." [GOC:ai, GOC:signaling, PMID:10506570] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0001566 +name: non-kinase phorbol ester receptor activity +namespace: molecular_function +def: "Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity." [PMID:10506570] +is_a: GO:0001565 ! phorbol ester receptor activity + +[Term] +id: GO:0001567 +name: cholesterol 25-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O." [EC:1.14.99.38, RHEA:21104] +synonym: "cholesterol 25-monooxygenase activity" EXACT [EC:1.14.99.38] +synonym: "cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity" EXACT [EC:1.14.99.38] +xref: EC:1.14.99.38 +xref: KEGG_REACTION:R07218 +xref: MetaCyc:1.14.99.38-RXN +xref: RHEA:21104 +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0001568 +name: blood vessel development +namespace: biological_process +def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001944 ! vasculature development + +[Term] +id: GO:0001569 +name: branching involved in blood vessel morphogenesis +namespace: biological_process +def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph] +synonym: "patterning of blood vessels" BROAD [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: part_of GO:0048514 ! blood vessel morphogenesis +relationship: part_of GO:0001525 ! angiogenesis + +[Term] +id: GO:0001570 +name: vasculogenesis +namespace: biological_process +def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798] +synonym: "vascular morphogenesis" EXACT [] +xref: Wikipedia:Vasculogenesis +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048514 ! blood vessel morphogenesis + +[Term] +id: GO:0001571 +name: non-tyrosine kinase fibroblast growth factor receptor activity +namespace: molecular_function +def: "Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity." [GOC:signaling, PMID:11418238] +synonym: "non-tyrosine kinase FGF receptor activity" EXACT [] +synonym: "non-tyrosine kinase FGFR activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0001572 +name: lactosylceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides." [ISBN:0198506732, ISBN:0471586501] +synonym: "lactosylceramide anabolism" EXACT [] +synonym: "lactosylceramide biosynthesis" EXACT [] +synonym: "lactosylceramide formation" EXACT [] +synonym: "lactosylceramide synthesis" EXACT [] +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +is_a: GO:0046478 ! lactosylceramide metabolic process +is_a: GO:0046513 ! ceramide biosynthetic process + +[Term] +id: GO:0001573 +name: ganglioside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues." [ISBN:0198506732] +synonym: "ganglioside metabolism" EXACT [] +is_a: GO:0006672 ! ceramide metabolic process +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0001574 +name: ganglioside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues." [ISBN:0198506732] +synonym: "ganglioside anabolism" EXACT [] +synonym: "ganglioside biosynthesis" EXACT [] +synonym: "ganglioside formation" EXACT [] +synonym: "ganglioside synthesis" EXACT [] +is_a: GO:0001573 ! ganglioside metabolic process +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +is_a: GO:0046513 ! ceramide biosynthetic process + +[Term] +id: GO:0001575 +name: globoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes." [ISBN:0198506732] +synonym: "globoside metabolism" EXACT [] +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0001576 +name: globoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)." [ISBN:0198506732] +synonym: "globoside anabolism" EXACT [] +synonym: "globoside biosynthesis" EXACT [] +synonym: "globoside formation" EXACT [] +synonym: "globoside synthesis" EXACT [] +is_a: GO:0001575 ! globoside metabolic process +is_a: GO:0006688 ! glycosphingolipid biosynthetic process + +[Term] +id: GO:0001577 +name: obsolete galectin +namespace: molecular_function +def: "OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars." [PMID:9786891] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "galectin" EXACT [] +synonym: "S-type lectin" EXACT [] +is_obsolete: true +consider: GO:0007157 +consider: GO:0016936 + +[Term] +id: GO:0001578 +name: microtubule bundle formation +namespace: biological_process +def: "A process that results in a parallel arrangement of microtubules." [GOC:dph] +synonym: "microtubule bundling" EXACT [] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0001579 +name: medium-chain fatty acid transport +namespace: biological_process +def: "The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12." [GOC:ai] +is_a: GO:0015908 ! fatty acid transport + +[Term] +id: GO:0001580 +name: detection of chemical stimulus involved in sensory perception of bitter taste +namespace: biological_process +def: "The series of events required for a bitter taste stimulus to be received and converted to a molecular signal." [GOC:go_curators] +synonym: "bitter taste detection" EXACT [] +synonym: "perception of bitter taste, detection of chemical stimulus" EXACT [] +synonym: "perception of bitter taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of bitter taste" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of bitter taste" EXACT [] +synonym: "sensory transduction of bitter taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of bitter taste" EXACT [] +is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050913 ! sensory perception of bitter taste +relationship: part_of GO:0050913 ! sensory perception of bitter taste + +[Term] +id: GO:0001581 +name: detection of chemical stimulus involved in sensory perception of sour taste +namespace: biological_process +def: "The series of events required for a sour taste stimulus to be received and converted to a molecular signal." [GOC:go_curators] +synonym: "perception of sour taste, detection of chemical stimulus" EXACT [] +synonym: "perception of sour taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of sour taste" EXACT [] +synonym: "sensory detection of sour taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of sour taste" EXACT [] +synonym: "sensory transduction of sour taste" EXACT [] +synonym: "sour taste detection" EXACT [] +is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050915 ! sensory perception of sour taste +relationship: part_of GO:0050915 ! sensory perception of sour taste + +[Term] +id: GO:0001582 +name: detection of chemical stimulus involved in sensory perception of sweet taste +namespace: biological_process +def: "The series of events required for a sweet taste stimulus to be received and converted to a molecular signal." [GOC:go_curators] +synonym: "perception of sweet taste, detection of chemical stimulus" EXACT [] +synonym: "perception of sweet taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of sweet taste" EXACT [] +synonym: "sensory detection of sweet taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of sweet taste" EXACT [] +synonym: "sensory transduction of sweet taste" EXACT [] +synonym: "sweet taste detection" EXACT [] +is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050916 ! sensory perception of sweet taste +relationship: part_of GO:0050916 ! sensory perception of sweet taste + +[Term] +id: GO:0001583 +name: detection of chemical stimulus involved in sensory perception of salty taste +namespace: biological_process +def: "The series of events required for a salty taste stimulus to be received and converted to a molecular signal." [GOC:go_curators] +synonym: "perception of salty taste, detection of chemical stimulus" EXACT [] +synonym: "perception of salty taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "salty taste detection" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of salty taste" EXACT [] +synonym: "sensory detection of salty taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of salty taste" EXACT [] +synonym: "sensory transduction of salty taste" EXACT [] +is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050914 ! sensory perception of salty taste +relationship: part_of GO:0050914 ! sensory perception of salty taste + +[Term] +id: GO:0001584 +name: obsolete rhodopsin-like receptor activity +namespace: molecular_function +alt_id: GO:0001620 +def: "OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor." [GOC:dph, GOC:mah, GOC:tb, IUPHAR_GPCR:1505] +comment: This term was made obsolete because it represents a gene product and is named based on protein features. +synonym: "Class A G protein coupled receptor" EXACT [] +synonym: "Class A G-protein coupled receptor" EXACT [] +synonym: "Class A GPCR" EXACT [] +synonym: "class A orphan receptor activity" EXACT [] +synonym: "rhodopsin-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001586 +name: Gi/o-coupled serotonin receptor activity +namespace: molecular_function +def: "Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels." [GOC:mah, PMID:18571247] +synonym: "5-HT1 receptor activity" EXACT [GOC:bf] +synonym: "serotonin receptor activity, coupled via Gi/o" EXACT [GOC:bf] +is_a: GO:0004993 ! G protein-coupled serotonin receptor activity + +[Term] +id: GO:0001587 +name: Gq/11-coupled serotonin receptor activity +namespace: molecular_function +def: "Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels." [GOC:bf, GOC:mah, PMID:18571247, PMID:18703043] +synonym: "5-HT2 receptor activity" BROAD [GOC:bf] +synonym: "serotonin receptor activity, coupled via Gq/11" EXACT [GOC:bf] +is_a: GO:0004993 ! G protein-coupled serotonin receptor activity + +[Term] +id: GO:0001588 +name: dopamine neurotransmitter receptor activity, coupled via Gs +namespace: molecular_function +alt_id: GO:0001589 +alt_id: GO:0001590 +def: "Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity." [GOC:mah, ISBN:0953351033, IUPHAR_RECEPTOR:2252, IUPHAR_RECEPTOR:2260] +synonym: "dopamine D1 receptor activity" NARROW [GOC:bf] +synonym: "dopamine D5 receptor activity" NARROW [GOC:bf] +is_a: GO:0004952 ! dopamine neurotransmitter receptor activity + +[Term] +id: GO:0001591 +name: dopamine neurotransmitter receptor activity, coupled via Gi/Go +namespace: molecular_function +alt_id: GO:0001592 +alt_id: GO:0001593 +alt_id: GO:0001670 +def: "Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity." [GOC:mah, ISBN:0953351033, IUPHAR_RECEPTOR:2254, IUPHAR_RECEPTOR:2256, IUPHAR_RECEPTOR:2258] +synonym: "dopamine D2 receptor activity" NARROW [GOC:bf] +synonym: "dopamine D3 receptor activity" NARROW [GOC:bf] +synonym: "dopamine D4 receptor activity" NARROW [GOC:bf] +is_a: GO:0004952 ! dopamine neurotransmitter receptor activity + +[Term] +id: GO:0001594 +name: trace-amine receptor activity +namespace: molecular_function +def: "Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals." [GOC:mah, PMID:19325074] +is_a: GO:0008227 ! G protein-coupled amine receptor activity + +[Term] +id: GO:0001595 +name: angiotensin receptor activity +namespace: molecular_function +def: "Combining with angiotensin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0038166 ! angiotensin-activated signaling pathway + +[Term] +id: GO:0001596 +name: angiotensin type I receptor activity +namespace: molecular_function +def: "An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms." [GOC:mah, PMID:10977869] +synonym: "PLC-activating angiotensin receptor activity" EXACT [GOC:bf] +is_a: GO:0001595 ! angiotensin receptor activity +relationship: part_of GO:0086097 ! phospholipase C-activating angiotensin-activated signaling pathway + +[Term] +id: GO:0001597 +name: obsolete apelin-like receptor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because the function it represents does not exist. +synonym: "apelin-like receptor" EXACT [] +synonym: "APJ-like receptor" EXACT [] +is_obsolete: true +consider: GO:0031704 + +[Term] +id: GO:0001598 +name: obsolete chemokine receptor-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "chemokine receptor-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001601 +name: peptide YY receptor activity +namespace: molecular_function +def: "Combining with gut peptide YY to initiate a change in cell activity." [PMID:9315606] +is_a: GO:0004983 ! neuropeptide Y receptor activity + +[Term] +id: GO:0001602 +name: pancreatic polypeptide receptor activity +namespace: molecular_function +def: "Combining with pancreatic polypeptide PP to initiate a change in cell activity." [PMID:9315606] +is_a: GO:0004983 ! neuropeptide Y receptor activity + +[Term] +id: GO:0001603 +name: obsolete vasopressin-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:curators] +synonym: "vasopressin-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001604 +name: urotensin II receptor activity +namespace: molecular_function +def: "Combining with urotensin II to initiate a change in cell activity." [GOC:mah, PMID:15102493] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0001605 +name: adrenomedullin receptor activity +namespace: molecular_function +def: "Combining with adrenomedullin to initiate a change in cell activity." [GOC:ai] +synonym: "G10D receptor" NARROW [] +is_a: GO:0097642 ! calcitonin family receptor activity + +[Term] +id: GO:0001606 +name: obsolete GPR37/endothelin B-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "GPR37/endothelin B-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001607 +name: neuromedin U receptor activity +namespace: molecular_function +def: "Combining with neuromedin U to initiate a change in cell activity." [GOC:ai] +synonym: "NMUR activity" EXACT [] +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: has_part GO:0042924 ! neuromedin U binding + +[Term] +id: GO:0001608 +name: G protein-coupled nucleotide receptor activity +namespace: molecular_function +def: "Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph, IUPHAR_GPCR:1294] +synonym: "G protein coupled nucleotide receptor activity" EXACT [] +synonym: "G-protein coupled nucleotide receptor activity" EXACT [] +synonym: "nucleotide receptor activity, G protein coupled" EXACT [] +synonym: "nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0001609 +name: G protein-coupled adenosine receptor activity +namespace: molecular_function +alt_id: GO:0001610 +alt_id: GO:0001611 +alt_id: GO:0001612 +alt_id: GO:0001613 +alt_id: GO:0008501 +def: "Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:mah, PMID:9755289] +synonym: "A1 adenosine receptor activity, G protein coupled" NARROW [] +synonym: "A1 adenosine receptor activity, G-protein coupled" NARROW [] +synonym: "A2A adenosine receptor activity, G protein coupled" NARROW [] +synonym: "A2A adenosine receptor activity, G-protein coupled" NARROW [] +synonym: "A2B adenosine receptor activity, G protein coupled" NARROW [] +synonym: "A2B adenosine receptor activity, G-protein coupled" NARROW [] +synonym: "A3 adenosine receptor activity, G protein coupled" NARROW [] +synonym: "A3 adenosine receptor activity, G-protein coupled" NARROW [] +synonym: "adenosine nucleotide receptor" BROAD [] +synonym: "adenosine receptor activity, G protein coupled" EXACT [] +synonym: "adenosine receptor activity, G-protein coupled" EXACT [GOC:bf] +synonym: "G protein coupled A1 adenosine receptor activity" NARROW [] +synonym: "G protein coupled A2A adenosine receptor activity" NARROW [] +synonym: "G protein coupled A2B adenosine receptor activity" NARROW [] +synonym: "G protein coupled A3 adenosine receptor activity" NARROW [] +synonym: "G protein coupled adenosine receptor activity" EXACT [] +synonym: "G-protein coupled adenosine receptor activity" EXACT [] +synonym: "G-protein-coupled A1 adenosine receptor activity" NARROW [] +synonym: "G-protein-coupled A2A adenosine receptor activity" NARROW [] +synonym: "G-protein-coupled A2B adenosine receptor activity" NARROW [] +synonym: "G-protein-coupled A3 adenosine receptor activity" NARROW [] +synonym: "P1 receptor" EXACT [PMID:9755289] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: part_of GO:0001973 ! G protein-coupled adenosine receptor signaling pathway + +[Term] +id: GO:0001614 +name: purinergic nucleotide receptor activity +namespace: molecular_function +alt_id: GO:0035586 +def: "Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +synonym: "P2 receptor" RELATED [PMID:9755289] +synonym: "purinergic receptor activity" RELATED [] +synonym: "purinoceptor" EXACT [PMID:9755289] +synonym: "purinoreceptor" EXACT [PMID:9755289] +is_a: GO:0016502 ! nucleotide receptor activity +relationship: has_part GO:0017076 ! purine nucleotide binding +relationship: part_of GO:0035590 ! purinergic nucleotide receptor signaling pathway +created_by: bf +creation_date: 2010-10-22T10:57:12Z + +[Term] +id: GO:0001615 +name: obsolete thyrotropin releasing hormone and secretagogue-like receptors activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "thyrotropin releasing hormone and secretagogue-like receptors activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001616 +name: growth hormone secretagogue receptor activity +namespace: molecular_function +def: "Combining with ghrelin to initiate a change in cell activity." [GOC:mah, PMID:17983853] +synonym: "ghrelin receptor activity" EXACT [GOC:mah, PMID:17983853] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0001617 +name: obsolete growth hormone secretagogue-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "growth hormone secretagogue-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001618 +name: virus receptor activity +namespace: molecular_function +def: "Combining with a virus component and mediating entry of the virus into the cell." [GOC:bf, GOC:dph, PMID:7621403, UniProtKB-KW:KW-1183] +subset: goslim_chembl +synonym: "viral receptor activity" EXACT [] +is_a: GO:0140272 ! exogenous protein binding +relationship: part_of GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0001619 +name: obsolete lysosphingolipid and lysophosphatidic acid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity." [GOC:dph] +synonym: "lysosphingolipid and lysophosphatidic acid receptor activity" EXACT [] +is_obsolete: true +consider: GO:0038036 +consider: GO:0070915 + +[Term] +id: GO:0001621 +name: G protein-coupled ADP receptor activity +namespace: molecular_function +alt_id: GO:0045032 +def: "Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:11196645] +synonym: "ADP receptor activity" BROAD [] +synonym: "ADP-activated adenosine receptor activity" RELATED [] +synonym: "ADP-activated nucleotide receptor activity" BROAD [] +synonym: "K101 receptor" NARROW [] +synonym: "platelet ADP receptor activity" NARROW [GOC:mah] +is_a: GO:0045028 ! G protein-coupled purinergic nucleotide receptor activity +relationship: has_part GO:0043531 ! ADP binding + +[Term] +id: GO:0001626 +name: nociceptin receptor activity +namespace: molecular_function +def: "Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein." [GOC:bf, GOC:mah, PMID:18670432] +synonym: "nociceptin/orphanin-FQ receptor activity" EXACT [GOC:bf] +synonym: "OFQ receptor activity" EXACT [PR:000012940] +synonym: "ORPH receptor" EXACT [] +synonym: "orphanin-FQ receptor activity" EXACT [GOC:bf] +synonym: "X-opioid receptor activity" RELATED [GOC:bf] +is_a: GO:0004985 ! opioid receptor activity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0001627 +name: obsolete leucine-rich G-protein receptor-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "leucine-rich G protein receptor-like receptor activity" EXACT [] +synonym: "leucine-rich G-protein receptor-like receptor activity" EXACT [] +synonym: "LGR-like receptor" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001628 +name: obsolete gastropyloric receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the gastropyloric receptor is a type of neuron. +synonym: "gastropyloric receptor activity" EXACT [] +synonym: "GPR receptor" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001629 +name: obsolete G-protein receptor 45-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "G protein receptor 45-like receptor activity" EXACT [] +synonym: "G-protein receptor 45-like receptor activity" EXACT [] +synonym: "GPR45-like receptor" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001630 +name: obsolete GP40-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "GP40-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001631 +name: cysteinyl leukotriene receptor activity +namespace: molecular_function +def: "Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine." [GOC:ai, ISBN:0198506732] +synonym: "CysLT receptor" EXACT [] +is_a: GO:0004974 ! leukotriene receptor activity + +[Term] +id: GO:0001632 +name: leukotriene B4 receptor activity +namespace: molecular_function +def: "Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate." [GOC:ai, ISBN:0198506732] +synonym: "BLT receptor" NARROW [] +is_a: GO:0004974 ! leukotriene receptor activity + +[Term] +id: GO:0001633 +name: obsolete secretin-like receptor activity +namespace: molecular_function +alt_id: GO:0001638 +def: "OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor." [GOC:mah] +comment: This term was made obsolete because it represents a gene product and is named based on protein features. +synonym: "class B G protein coupled receptor" EXACT [] +synonym: "class B G-protein coupled receptor" EXACT [] +synonym: "class B GPCR" EXACT [] +synonym: "class B orphan receptor activity" EXACT [] +synonym: "secretin-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001634 +name: pituitary adenylate cyclase-activating polypeptide receptor activity +namespace: molecular_function +alt_id: GO:0016522 +def: "A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide." [GOC:dph, GOC:tb] +synonym: "PACAP receptor" EXACT [] +synonym: "pituitary adenylate cyclase activating polypeptide receptor" EXACT [] +synonym: "pituitary adenylate cyclase activating protein receptor activity" EXACT [GOC:dph, GOC:tb] +synonym: "pituitary adenylate cyclase-activating peptide receptor activity" RELATED [] +synonym: "pituitary adenylate cyclase-activating polypeptide receptor activity" RELATED [] +synonym: "pituitary adenylyl cyclase activating protein receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0001635 +name: calcitonin gene-related peptide receptor activity +namespace: molecular_function +def: "Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity." [GOC:mah, PMID:12037140] +synonym: "calcitonin gene-related polypeptide receptor activity" EXACT [] +synonym: "CGRP receptor" EXACT [] +xref: Wikipedia:CALCRL +is_a: GO:0097642 ! calcitonin family receptor activity + +[Term] +id: GO:0001636 +name: obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0001637 +name: G protein-coupled chemoattractant receptor activity +namespace: molecular_function +def: "Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:mah] +synonym: "G protein chemoattractant receptor activity" EXACT [] +synonym: "G-protein chemoattractant receptor activity" EXACT [GOC:bf] +synonym: "G-protein coupled chemoattractant receptor activity" EXACT [] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0001639 +name: PLC activating G protein-coupled glutamate receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system." [PMID:9016303] +synonym: "Group I metabotropic glutamate receptor" RELATED [] +synonym: "group I metabotropic glutamate receptor activity" RELATED [] +synonym: "phospholipase C activating metabotropic glutamate receptor activity" EXACT [] +synonym: "PLC activating G-protein coupled glutamate receptor activity" EXACT [] +synonym: "PLC activating metabotropic glutamate receptor activity" EXACT [GOC:bf] +is_a: GO:0098988 ! G protein-coupled glutamate receptor activity +relationship: part_of GO:0007206 ! phospholipase C-activating G protein-coupled glutamate receptor signaling pathway + +[Term] +id: GO:0001640 +name: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity +namespace: molecular_function +def: "Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity." [GOC:bf, GOC:dph] +synonym: "adenylate cyclase inhibiting metabotropic glutamate receptor activity" RELATED [GOC:bf] +synonym: "adenylyl cyclase inhibiting metabotropic glutamate receptor activity" EXACT [] +is_a: GO:0098988 ! G protein-coupled glutamate receptor activity +relationship: part_of GO:0007196 ! adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway + +[Term] +id: GO:0001641 +name: group II metabotropic glutamate receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity." [GOC:dph] +is_a: GO:0001640 ! adenylate cyclase inhibiting G protein-coupled glutamate receptor activity + +[Term] +id: GO:0001642 +name: group III metabotropic glutamate receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity." [PMID:9016303] +is_a: GO:0001640 ! adenylate cyclase inhibiting G protein-coupled glutamate receptor activity + +[Term] +id: GO:0001646 +name: cAMP receptor activity +namespace: molecular_function +alt_id: GO:0001644 +def: "Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:pg] +synonym: "3',5' cAMP receptor activity" EXACT [] +synonym: "3',5'-cAMP receptor activity" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate receptor activity" EXACT [] +synonym: "class E G protein coupled receptor" BROAD [] +synonym: "class E G-protein coupled receptor" BROAD [] +synonym: "class E GPCR" BROAD [] +synonym: "cyclic AMP receptor activity" EXACT [] +is_a: GO:0045028 ! G protein-coupled purinergic nucleotide receptor activity +relationship: has_part GO:0030552 ! cAMP binding + +[Term] +id: GO:0001647 +name: G protein-coupled cytokinin receptor activity +namespace: molecular_function +def: "Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph] +synonym: "cytokinin receptor activity, G-protein coupled" EXACT [GOC:bf] +synonym: "G protein coupled cytokinin receptor activity" EXACT [] +synonym: "G-protein coupled cytokinin receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0009884 ! cytokinin receptor activity + +[Term] +id: GO:0001648 +name: proteinase activated receptor activity +namespace: molecular_function +def: "A G protein-coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor." [GOC:mah, PMID:11356985] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0001649 +name: osteoblast differentiation +namespace: biological_process +def: "The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone." [CL:0000062, GO_REF:0000034, GOC:jid] +synonym: "osteoblast cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001503 ! ossification + +[Term] +id: GO:0001650 +name: fibrillar center +namespace: cellular_component +def: "A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures." [PMID:10754561] +synonym: "fibrillar centre" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0001651 +name: dense fibrillar component +namespace: cellular_component +def: "A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins." [PMID:10754561] +synonym: "pars fibrosa" BROAD [NIF_Subcellular:sao1841764412] +xref: NIF_Subcellular:sao1841764412 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0001652 +name: granular component +namespace: cellular_component +def: "A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm." [PMID:10754561] +synonym: "pars granulosa" BROAD [NIF_Subcellular:sao1217793903] +xref: NIF_Subcellular:sao1217793903 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0001653 +name: peptide receptor activity +namespace: molecular_function +def: "Combining with an extracellular or intracellular peptide to initiate a change in cell activity." [GOC:jl] +synonym: "endogenous peptide receptor activity" NARROW [] +synonym: "exogenous peptide receptor activity" NARROW [] +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0042277 ! peptide binding + +[Term] +id: GO:0001654 +name: eye development +namespace: biological_process +alt_id: GO:0042460 +def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl] +xref: Wikipedia:Eye_development +is_a: GO:0007423 ! sensory organ development +relationship: part_of GO:0150063 ! visual system development + +[Term] +id: GO:0001655 +name: urogenital system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0001656 +name: metanephros development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752] +is_a: GO:0001822 ! kidney development + +[Term] +id: GO:0001657 +name: ureteric bud development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0072164 ! mesonephric tubule development + +[Term] +id: GO:0001658 +name: branching involved in ureteric bud morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378] +synonym: "ureteric bud branching" EXACT [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0001763 ! morphogenesis of a branching structure +intersection_of: part_of GO:0060675 ! ureteric bud morphogenesis +relationship: part_of GO:0060675 ! ureteric bud morphogenesis + +[Term] +id: GO:0001659 +name: temperature homeostasis +namespace: biological_process +def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl] +synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb] +xref: Wikipedia:Thermoregulation +is_a: GO:0048871 ! multicellular organismal homeostasis + +[Term] +id: GO:0001660 +name: fever generation +namespace: biological_process +def: "The heat generation process that results in a rise in body temperature above the normal, often as a response to infection." [GOC:dph, GOC:jl] +synonym: "pyrexia" BROAD [] +xref: Wikipedia:Fever +is_a: GO:0006953 ! acute-phase response +is_a: GO:0031649 ! heat generation + +[Term] +id: GO:0001661 +name: conditioned taste aversion +namespace: biological_process +def: "A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus." [GOC:dph, PMID:9920659] +xref: Wikipedia:Conditioned_taste_aversion +xref: Wikipedia:Taste_aversion +is_a: GO:0007631 ! feeding behavior +is_a: GO:0008306 ! associative learning + +[Term] +id: GO:0001662 +name: behavioral fear response +namespace: biological_process +def: "An acute behavioral change resulting from a perceived external threat." [GOC:dph, PMID:9920659] +synonym: "behavioural fear response" EXACT [] +is_a: GO:0002209 ! behavioral defense response +is_a: GO:0042596 ! fear response + +[Term] +id: GO:0001664 +name: G protein-coupled receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G protein-coupled receptor." [GOC:ceb, GOC:dph] +synonym: "G protein coupled receptor binding" EXACT [] +synonym: "G protein coupled receptor ligand" NARROW [] +synonym: "G-protein coupled receptor binding" EXACT [GOC:bf] +synonym: "G-protein-coupled receptor ligand" NARROW [] +xref: Reactome:R-HSA-500717 "Activation of GRIK3 homomer" +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0001665 +name: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein." [EC:2.4.99.3] +synonym: "CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.3] +synonym: "GalNAc alpha-2,6-sialyltransferase I activity" EXACT [EC:2.4.99.3] +xref: EC:2.4.99.3 +xref: MetaCyc:2.4.99.3-RXN +xref: Reactome:R-HSA-4084980 "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)" +xref: Reactome:R-HSA-9603991 "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG" +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0001666 +name: response to hypoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd] +comment: Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. +synonym: "response to hypoxic stress" EXACT [] +synonym: "response to intermittent hypoxia" NARROW [] +synonym: "response to lowered oxygen tension" EXACT [] +synonym: "response to sustained hypoxia" NARROW [] +is_a: GO:0006950 ! response to stress +is_a: GO:0036293 ! response to decreased oxygen levels + +[Term] +id: GO:0001667 +name: ameboidal-type cell migration +namespace: biological_process +def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph] +comment: Note that this term refers to a mode of migration rather than to any particular cell type. +synonym: "ameboid cell migration" EXACT [] +synonym: "amoeboid cell migration" EXACT [] +synonym: "amoeboidal cell migration" EXACT [] +is_a: GO:0016477 ! cell migration + +[Term] +id: GO:0001669 +name: acrosomal vesicle +namespace: cellular_component +def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732] +synonym: "acrosomal granule" EXACT [GOC:sart] +synonym: "acrosome" EXACT [GOC:dph] +xref: Wikipedia:Acrosome +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0001671 +name: ATPase activator activity +namespace: molecular_function +def: "Binds to and increases the ATP hydrolysis activity of an ATPase." [GOC:ajp] +synonym: "ATPase stimulator activity" EXACT [] +xref: Reactome:R-HSA-5251955 "HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm" +xref: Reactome:R-HSA-5251959 "HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol" +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0060590 ! ATPase regulator activity +relationship: part_of GO:0032781 ! positive regulation of ATPase activity +relationship: positively_regulates GO:0016887 ! ATPase activity + +[Term] +id: GO:0001672 +name: regulation of chromatin assembly or disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] +synonym: "regulation of chromatin assembly/disassembly" EXACT [] +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006333 ! chromatin assembly or disassembly +relationship: regulates GO:0006333 ! chromatin assembly or disassembly + +[Term] +id: GO:0001673 +name: male germ cell nucleus +namespace: cellular_component +alt_id: GO:0043081 +def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu] +synonym: "male germ-cell nucleus" EXACT [] +is_a: GO:0043073 ! germ cell nucleus + +[Term] +id: GO:0001674 +name: female germ cell nucleus +namespace: cellular_component +alt_id: GO:0043080 +def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd] +synonym: "female germ-cell nucleus" EXACT [] +is_a: GO:0043073 ! germ cell nucleus + +[Term] +id: GO:0001675 +name: acrosome assembly +namespace: biological_process +def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0033363 ! secretory granule organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0007286 ! spermatid development + +[Term] +id: GO:0001676 +name: long-chain fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:ajp] +synonym: "long-chain fatty acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0001677 +name: formation of translation initiation ternary complex +namespace: biological_process +def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd] +synonym: "translation initiation ternary complex assembly" EXACT [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0006413 ! translational initiation + +[Term] +id: GO:0001678 +name: cellular glucose homeostasis +namespace: biological_process +def: "A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "cell glucose homeostasis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042593 ! glucose homeostasis +is_a: GO:0055082 ! cellular chemical homeostasis + +[Term] +id: GO:0001680 +name: tRNA 3'-terminal CCA addition +namespace: biological_process +def: "Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition." [EC:2.7.7.72, GOC:go_curators] +synonym: "-C-C-A pyrophosphorylase activity" RELATED [EC:2.7.7.72] +synonym: "ATP(CTP)-tRNA nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "ATP(CTP):tRNA nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "CCA tRNA nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "CCA-adding enzyme activity" EXACT [EC:2.7.7.72] +synonym: "CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity" EXACT [EC:2.7.7.72] +synonym: "CTP(ATP):tRNA nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "CTP:tRNA cytidylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity" EXACT [EC:2.7.7.72] +synonym: "ribonucleic cytidylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "transfer ribonucleate adenyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "transfer ribonucleate adenylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "transfer ribonucleate cytidylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "transfer ribonucleate nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "transfer ribonucleic acid nucleotidyl transferase activity" BROAD [EC:2.7.7.72] +synonym: "transfer ribonucleic adenylyl (cytidylyl) transferase activity" RELATED [EC:2.7.7.72] +synonym: "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "transfer RNA adenylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "transfer-RNA nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +synonym: "tRNA adenylyl(cytidylyl)transferase activity" BROAD [EC:2.7.7.72] +synonym: "tRNA CCA-diphosphorylase activity" RELATED [EC:2.7.7.72] +synonym: "tRNA cytidylyltransferase activity" NARROW [EC:2.7.7.72] +synonym: "tRNA-nucleotidyltransferase activity" BROAD [EC:2.7.7.72] +xref: KEGG_REACTION:R09382 +xref: MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN +is_a: GO:0042780 ! tRNA 3'-end processing +relationship: has_part GO:0052927 ! CTP:tRNA cytidylyltransferase activity +relationship: has_part GO:0052928 ! CTP:3'-cytidine-tRNA cytidylyltransferase activity +relationship: has_part GO:0052929 ! ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity + +[Term] +id: GO:0001681 +name: sialate O-acetylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate." [EC:3.1.1.53, PMID:1991039] +synonym: "N-acetylneuraminate acetyltransferase activity" EXACT [EC:3.1.1.53] +synonym: "N-acyl-O-acetylneuraminate O-acetylhydrolase activity" EXACT [EC:3.1.1.53] +synonym: "sialate 9(4)-O-acetylesterase activity" EXACT [] +xref: EC:3.1.1.53 +xref: MetaCyc:SIALATE-O-ACETYLESTERASE-RXN +is_a: GO:0008126 ! acetylesterase activity + +[Term] +id: GO:0001682 +name: tRNA 5'-leader removal +namespace: biological_process +def: "Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P." [PMID:11592395] +synonym: "tRNA 5' leader removal" EXACT [] +is_a: GO:0099116 ! tRNA 5'-end processing + +[Term] +id: GO:0001683 +name: obsolete axonemal dynein heavy chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "axonemal dynein heavy chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005858 + +[Term] +id: GO:0001684 +name: obsolete axonemal dynein intermediate chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "axonemal dynein intermediate chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005858 + +[Term] +id: GO:0001685 +name: obsolete axonemal dynein intermediate light chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "axonemal dynein intermediate light chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005858 + +[Term] +id: GO:0001686 +name: obsolete axonemal dynein light chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "axonemal dynein light chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005858 + +[Term] +id: GO:0001687 +name: obsolete cytoplasmic dynein heavy chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "cytoplasmic dynein heavy chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005868 + +[Term] +id: GO:0001688 +name: obsolete cytoplasmic dynein intermediate chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "cytoplasmic dynein intermediate chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005868 + +[Term] +id: GO:0001689 +name: obsolete cytoplasmic dynein intermediate light chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "cytoplasmic dynein intermediate light chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005868 + +[Term] +id: GO:0001690 +name: obsolete cytoplasmic dynein light chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "cytoplasmic dynein light chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005868 + +[Term] +id: GO:0001691 +name: pseudophosphatase activity +namespace: molecular_function +def: "Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues." [GOC:ajp] +is_a: GO:0019212 ! phosphatase inhibitor activity + +[Term] +id: GO:0001692 +name: histamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:jl, ISBN:0395825172] +synonym: "histamine metabolism" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0052803 ! imidazole-containing compound metabolic process +is_a: GO:0097164 ! ammonium ion metabolic process + +[Term] +id: GO:0001694 +name: histamine biosynthetic process +namespace: biological_process +alt_id: GO:0001693 +def: "The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:jl, ISBN:0395825172] +synonym: "histamine anabolism" EXACT [] +synonym: "histamine biosynthesis" EXACT [] +synonym: "histamine formation" EXACT [] +synonym: "histamine synthesis" EXACT [] +is_a: GO:0001692 ! histamine metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0001695 +name: histamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:jl, ISBN:0395825172] +synonym: "histamine breakdown" EXACT [] +synonym: "histamine catabolism" EXACT [] +synonym: "histamine degradation" EXACT [] +is_a: GO:0001692 ! histamine metabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:0052805 ! imidazole-containing compound catabolic process + +[Term] +id: GO:0001696 +name: gastric acid secretion +namespace: biological_process +def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd] +synonym: "hydrochloric acid secretion" NARROW [] +is_a: GO:0022600 ! digestive system process +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0001697 +name: histamine-induced gastric acid secretion +namespace: biological_process +def: "The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP." [GOC:hjd] +is_a: GO:0001696 ! gastric acid secretion + +[Term] +id: GO:0001698 +name: gastrin-induced gastric acid secretion +namespace: biological_process +def: "The regulated release of gastric acid induced by the interaction of gastrin with its receptor." [GOC:hjd] +is_a: GO:0001696 ! gastric acid secretion +relationship: has_part GO:0015054 ! gastrin receptor activity + +[Term] +id: GO:0001699 +name: acetylcholine-induced gastric acid secretion +namespace: biological_process +def: "The regulated release of gastric acid by parietal cells in response to acetylcholine." [GOC:hjd] +is_a: GO:0001696 ! gastric acid secretion +relationship: has_part GO:0015464 ! acetylcholine receptor activity +relationship: part_of GO:1905145 ! cellular response to acetylcholine + +[Term] +id: GO:0001700 +name: embryonic development via the syncytial blastoderm +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0009792 ! embryo development ending in birth or egg hatching + +[Term] +id: GO:0001701 +name: in utero embryonic development +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0001702 +name: gastrulation with mouth forming second +namespace: biological_process +alt_id: GO:0010003 +alt_id: GO:0048276 +def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu] +synonym: "deuterostomic gastrulation" EXACT [GOC:dph] +is_a: GO:0007369 ! gastrulation + +[Term] +id: GO:0001703 +name: gastrulation with mouth forming first +namespace: biological_process +def: "A gastrulation process in which the initial invagination becomes the mouth and the anus forms second." [GOC:go_curators, GOC:mtg_sensu] +synonym: "protostomic gastrulation" NARROW [GOC:dph] +is_a: GO:0007369 ! gastrulation + +[Term] +id: GO:0001704 +name: formation of primary germ layer +namespace: biological_process +def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007369 ! gastrulation + +[Term] +id: GO:0001705 +name: ectoderm formation +namespace: biological_process +def: "The formation of ectoderm during gastrulation." [GOC:go_curators] +is_a: GO:0001704 ! formation of primary germ layer +relationship: part_of GO:0007398 ! ectoderm development + +[Term] +id: GO:0001706 +name: endoderm formation +namespace: biological_process +def: "The formation of the endoderm during gastrulation." [GOC:go_curators] +synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001704 ! formation of primary germ layer +relationship: part_of GO:0007492 ! endoderm development + +[Term] +id: GO:0001707 +name: mesoderm formation +namespace: biological_process +def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators] +is_a: GO:0001704 ! formation of primary germ layer +relationship: part_of GO:0048332 ! mesoderm morphogenesis + +[Term] +id: GO:0001708 +name: cell fate specification +namespace: biological_process +def: "The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:go_curators] +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0045165 ! cell fate commitment + +[Term] +id: GO:0001709 +name: cell fate determination +namespace: biological_process +def: "A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [ISBN:0878932437] +xref: Wikipedia:Cell_fate_determination +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0045165 ! cell fate commitment + +[Term] +id: GO:0001710 +name: mesodermal cell fate commitment +namespace: biological_process +def: "The cell differentiation process that results in commitment of a cell to become part of the mesoderm." [GOC:go_curators, ISBN:0878932437] +synonym: "mesoderm cell fate commitment" EXACT [] +is_a: GO:0060795 ! cell fate commitment involved in formation of primary germ layer +relationship: part_of GO:0048333 ! mesodermal cell differentiation + +[Term] +id: GO:0001711 +name: endodermal cell fate commitment +namespace: biological_process +def: "The cell differentiation process that results in commitment of a cell to become part of the endoderm." [GOC:go_curators, ISBN:0878932437] +synonym: "endoderm cell fate commitment" EXACT [] +is_a: GO:0060795 ! cell fate commitment involved in formation of primary germ layer +relationship: part_of GO:0035987 ! endodermal cell differentiation + +[Term] +id: GO:0001712 +name: ectodermal cell fate commitment +namespace: biological_process +def: "The cell differentiation process that results in commitment of a cell to become part of the ectoderm." [GOC:go_curators, ISBN:0878932437] +synonym: "ectoderm cell fate commitment" EXACT [] +is_a: GO:0060795 ! cell fate commitment involved in formation of primary germ layer +relationship: part_of GO:0001705 ! ectoderm formation +relationship: part_of GO:0010668 ! ectodermal cell differentiation + +[Term] +id: GO:0001713 +name: ectodermal cell fate determination +namespace: biological_process +def: "The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, ISBN:0878932437] +synonym: "ectoderm cell fate determination" EXACT [] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0001712 ! ectodermal cell fate commitment + +[Term] +id: GO:0001714 +name: endodermal cell fate specification +namespace: biological_process +def: "The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] +synonym: "endoderm cell fate specification" EXACT [] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0001711 ! endodermal cell fate commitment + +[Term] +id: GO:0001715 +name: ectodermal cell fate specification +namespace: biological_process +def: "The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] +synonym: "ectoderm cell fate specification" EXACT [] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0001712 ! ectodermal cell fate commitment + +[Term] +id: GO:0001716 +name: L-amino-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide." [EC:1.4.3.2] +synonym: "L-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.2] +synonym: "ophio-amino-acid oxidase activity" EXACT [EC:1.4.3.2] +xref: EC:1.4.3.2 +xref: MetaCyc:L-AMINO-ACID-OXIDASE-RXN +xref: Reactome:R-HSA-2160492 "IL4I1:FAD oxidises L-Phe to kPPV" +xref: RHEA:13781 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0001717 +name: conversion of seryl-tRNAsec to selenocys-tRNAsec +namespace: biological_process +def: "The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine." [ISBN:155581073X] +is_a: GO:0019988 ! charged-tRNA amino acid modification + +[Term] +id: GO:0001720 +name: conversion of lysyl-tRNA to pyrrolysyl-tRNA +namespace: biological_process +def: "The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate)." [PMID:12029131, PMID:12029132, PMID:12121639] +is_a: GO:0019988 ! charged-tRNA amino acid modification + +[Term] +id: GO:0001721 +name: obsolete intermediate filament associated protein +namespace: cellular_component +def: "OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks." [GOC:ajp, PMID:9484600] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "IFAP" EXACT [] +synonym: "intermediate filament associated protein" EXACT [] +is_obsolete: true +replaced_by: GO:0005882 + +[Term] +id: GO:0001722 +name: obsolete type I intermediate filament associated protein +namespace: cellular_component +def: "OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates." [GOC:ajp, PMID:9484600] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "type I intermediate filament associated protein" EXACT [] +is_obsolete: true +replaced_by: GO:0005882 + +[Term] +id: GO:0001723 +name: obsolete type II intermediate filament associated protein +namespace: cellular_component +def: "OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks." [GOC:ajp, PMID:9484600] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "type II intermediate filament associated protein" EXACT [] +is_obsolete: true +replaced_by: GO:0005882 + +[Term] +id: GO:0001724 +name: obsolete type III intermediate filament associated protein +namespace: cellular_component +def: "OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane." [GOC:ajp, PMID:9484600] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "type III intermediate filament associated protein" EXACT [] +is_obsolete: true +replaced_by: GO:0045098 + +[Term] +id: GO:0001725 +name: stress fiber +namespace: cellular_component +def: "A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber." [PMID:16651381] +synonym: "actin cable" RELATED [GOC:mah] +synonym: "stress fibre" EXACT [] +is_a: GO:0042641 ! actomyosin +is_a: GO:0097517 ! contractile actin filament bundle + +[Term] +id: GO:0001726 +name: ruffle +namespace: cellular_component +def: "Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork." [ISBN:0124325653] +synonym: "membrane ruffle" RELATED [] +is_a: GO:0120025 ! plasma membrane bounded cell projection +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0001727 +name: lipid kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of a simple or complex lipid." [GOC:hjd] +is_a: GO:0016301 ! kinase activity +relationship: part_of GO:0046834 ! lipid phosphorylation + +[Term] +id: GO:0001729 +name: ceramide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate." [EC:2.7.1.138] +synonym: "acylsphingosine kinase activity" EXACT [EC:2.7.1.138] +synonym: "ATP:ceramide 1-phosphotransferase activity" EXACT [EC:2.7.1.138] +xref: EC:2.7.1.138 +xref: MetaCyc:CERAMIDE-KINASE-RXN +xref: Reactome:R-HSA-1638845 "CERK phosphorylates CERA to form C1P" +xref: RHEA:17929 +is_a: GO:0001727 ! lipid kinase activity + +[Term] +id: GO:0001730 +name: 2'-5'-oligoadenylate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA." [ISBN:0198506732] +synonym: "(2-5')oligo(A) synthetase activity" EXACT [] +synonym: "2'-5' oligoadenylate synthetase activity" EXACT [] +synonym: "2-5A synthetase activity" EXACT [] +synonym: "oligo-2',5'-adenylate synthetase activity" EXACT [] +xref: EC:2.7.7.84 +xref: MetaCyc:RXN-10798 +xref: MetaCyc:RXN-13648 +xref: Reactome:R-HSA-8983680 "OAS1 produces oligoadenylates" +xref: Reactome:R-HSA-8985091 "OAS3 produces oligoadenylates" +xref: Reactome:R-HSA-8985104 "OAS2 produces oligoadenylates" +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0001731 +name: formation of translation preinitiation complex +namespace: biological_process +def: "The joining of the small ribosomal subunit, ternary complex, and mRNA." [GOC:hjd] +comment: See also the cellular component terms 'eukaryotic 43S preinitiation complex ; GO:0016282', 'eukaryotic 48S initiation complex ; GO:0033290', and their children. +synonym: "formation of translation pre-initiation complex" EXACT [] +synonym: "translation preinitiation complex assembly" EXACT [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0002183 ! cytoplasmic translational initiation + +[Term] +id: GO:0001732 +name: formation of cytoplasmic translation initiation complex +namespace: biological_process +def: "Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site." [GOC:hjd] +synonym: "cytoplasmic translation initiation complex assembly" EXACT [] +synonym: "formation of translation initiation complex" BROAD [] +synonym: "translation initiation complex assembly" BROAD [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0002183 ! cytoplasmic translational initiation + +[Term] +id: GO:0001733 +name: galactosylceramide sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate." [EC:2.8.2.11, PMID:10727929] +synonym: "3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "cerebroside sulfotransferase activity" EXACT [] +synonym: "galactocerebroside sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "galactolipid sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "galactosylceramide sulphotransferase activity" EXACT [] +synonym: "glycolipid sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "glycosphingolipid sulfotransferase activity" EXACT [EC:2.8.2.11] +synonym: "GSase" EXACT [EC:2.8.2.11] +xref: EC:2.8.2.11 +xref: MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN +xref: RHEA:20613 +is_a: GO:0050694 ! galactose 3-O-sulfotransferase activity + +[Term] +id: GO:0001734 +name: mRNA (N6-adenosine)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U." [GOC:hjd] +xref: Reactome:R-HSA-72095 "Internal Methylation of mRNA" +is_a: GO:0008174 ! mRNA methyltransferase activity + +[Term] +id: GO:0001735 +name: prenylcysteine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2." [GOC:hjd] +synonym: "prenylcysteine lyase activity" EXACT [EC:1.8.3.5] +synonym: "S-prenyl-L-cysteine:oxygen oxidoreductase activity" EXACT [EC:1.8.3.5] +xref: EC:1.8.3.5 +xref: MetaCyc:1.8.3.5-RXN +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0001736 +name: establishment of planar polarity +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates." [GOC:dph] +synonym: "establishment of planar cell polarity" NARROW [] +is_a: GO:0007164 ! establishment of tissue polarity +relationship: part_of GO:0001738 ! morphogenesis of a polarized epithelium + +[Term] +id: GO:0001737 +name: establishment of imaginal disc-derived wing hair orientation +namespace: biological_process +def: "Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction." [GOC:ascb_2009, GOC:dph, GOC:mtg_sensu, GOC:tb, PMID:11239465] +synonym: "establishment of wing hair orientation" EXACT [] +is_a: GO:0001736 ! establishment of planar polarity +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0035317 ! imaginal disc-derived wing hair organization + +[Term] +id: GO:0001738 +name: morphogenesis of a polarized epithelium +namespace: biological_process +def: "The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis." [GOC:dph] +synonym: "epithelial polarization" EXACT [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium + +[Term] +id: GO:0001739 +name: sex chromatin +namespace: cellular_component +def: "Chromatin that is part of a sex chromosome." [GOC:dos, ISBN:0198506732] +is_a: GO:0005720 ! nuclear heterochromatin +intersection_of: GO:0005720 ! nuclear heterochromatin +intersection_of: part_of GO:0000803 ! sex chromosome +relationship: part_of GO:0000803 ! sex chromosome + +[Term] +id: GO:0001740 +name: Barr body +namespace: cellular_component +def: "A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery." [GOC:hjd, GOC:mr, NIF_Subcellular:sao1571698684] +xref: NIF_Subcellular:sao1571698684 +xref: Wikipedia:Barr_body +is_a: GO:0000228 ! nuclear chromosome +is_a: GO:0000805 ! X chromosome +relationship: has_part GO:0098578 ! condensed chromatin of inactivated sex chromosome + +[Term] +id: GO:0001741 +name: XY body +namespace: cellular_component +def: "A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery." [GOC:hjd, GOC:mr, PMID:20622855, Wikipedia:XY_sex-determination_system] +is_a: GO:0000803 ! sex chromosome +relationship: has_part GO:0098578 ! condensed chromatin of inactivated sex chromosome +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0001742 +name: oenocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments." [GOC:go_curators] +synonym: "oenocyte cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0001743 +name: optic placode formation +namespace: biological_process +def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0001744 +name: optic lobe placode formation +namespace: biological_process +alt_id: GO:0007457 +def: "Establishment of the optic placode, a thickened area of densely packed ectoderm cells directly overlying the optic vesicle in the early embryo. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system." [GOC:mtg_sensu, PMID:8402833] +synonym: "optic lobe and Bolwig's organ precursor formation" EXACT [] +is_a: GO:0060788 ! ectodermal placode formation + +[Term] +id: GO:0001745 +name: compound eye morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] +synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386] +is_a: GO:0048592 ! eye morphogenesis +relationship: part_of GO:0048749 ! compound eye development + +[Term] +id: GO:0001746 +name: Bolwig's organ morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain." [http://sdb.bio.purdue.edu/fly/torstoll/tailess.htm#bolwigs, PMID:6185380] +is_a: GO:0048592 ! eye morphogenesis +relationship: part_of GO:0055034 ! Bolwig's organ development + +[Term] +id: GO:0001748 +name: optic lobe placode development +namespace: biological_process +alt_id: GO:0048049 +def: "The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:8402833] +synonym: "optic lobe and Bolwig's organ precursor development" EXACT [] +synonym: "optic placode development" BROAD [] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0001750 +name: photoreceptor outer segment +namespace: cellular_component +def: "The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins." [GOC:cilia, GOC:krc, GOC:pde, ISBN:0824072820, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097733 ! photoreceptor cell cilium + +[Term] +id: GO:0001751 +name: compound eye photoreceptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] +is_a: GO:0001754 ! eye photoreceptor cell differentiation +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0001752 +name: compound eye photoreceptor fate commitment +namespace: biological_process +alt_id: GO:0007459 +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments." [GOC:mtg_sensu] +is_a: GO:0042706 ! eye photoreceptor cell fate commitment +relationship: part_of GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0001753 +name: obsolete adult eye photoreceptor development (sensu Drosophila) +namespace: biological_process +def: "OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye." [GOC:go_curators] +comment: This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins. +synonym: "adult eye photoreceptor development (sensu Drosophila)" EXACT [] +is_obsolete: true +consider: GO:0042051 + +[Term] +id: GO:0001754 +name: eye photoreceptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] +is_a: GO:0046530 ! photoreceptor cell differentiation +relationship: part_of GO:0048592 ! eye morphogenesis + +[Term] +id: GO:0001755 +name: neural crest cell migration +namespace: biological_process +def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437] +is_a: GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0014032 ! neural crest cell development + +[Term] +id: GO:0001756 +name: somitogenesis +namespace: biological_process +def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544] +synonym: "formation of mesodermal clusters" EXACT systematic_synonym [] +xref: Wikipedia:Somitogenesis +is_a: GO:0009952 ! anterior/posterior pattern specification +is_a: GO:0035282 ! segmentation +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0043009 ! chordate embryonic development +relationship: part_of GO:0061053 ! somite development + +[Term] +id: GO:0001757 +name: somite specification +namespace: biological_process +def: "The process in which individual somites establish identity during embryogenesis." [GOC:dph] +is_a: GO:0007379 ! segment specification +is_a: GO:0009880 ! embryonic pattern specification +relationship: part_of GO:0001756 ! somitogenesis + +[Term] +id: GO:0001758 +name: retinal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal." [EC:1.2.1.36] +synonym: "cytosolic retinal dehydrogenase activity" EXACT [EC:1.2.1.36] +synonym: "retinal:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.36] +xref: EC:1.2.1.36 +xref: MetaCyc:RETINAL-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-5362522 "ALDHs oxidise atRAL to atRA" +xref: Reactome:R-HSA-5696101 "ALDH8A1 oxidises 9cRAL to 9cRA" +xref: RHEA:16177 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0001759 +name: organ induction +namespace: biological_process +def: "The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ." [ISBN:0878932437] +synonym: "induction of an organ" EXACT [] +is_a: GO:0003156 ! regulation of animal organ formation +is_a: GO:0031128 ! developmental induction +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +relationship: positively_regulates GO:0010092 ! specification of animal organ identity + +[Term] +id: GO:0001760 +name: aminocarboxymuconate-semialdehyde decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2)." [EC:4.1.1.45, RHEA:16557] +synonym: "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)" EXACT [EC:4.1.1.45] +synonym: "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity" EXACT [EC:4.1.1.45] +synonym: "2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity" EXACT [EC:4.1.1.45] +synonym: "ACMSD activity" EXACT [PMID:17288562] +synonym: "alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity" EXACT [EC:4.1.1.45] +synonym: "alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity" EXACT [EC:4.1.1.45] +synonym: "picolinic acid carboxylase activity" EXACT [EC:4.1.1.45] +synonym: "picolinic acid decarboxylase activity" EXACT [EC:4.1.1.45] +xref: EC:4.1.1.45 +xref: KEGG_REACTION:R04323 +xref: MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN +xref: RHEA:16557 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0001761 +name: beta-alanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid." [GOC:hjd] +synonym: "beta-alanine transporter activity" BROAD [] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +relationship: part_of GO:0001762 ! beta-alanine transport + +[Term] +id: GO:0001762 +name: beta-alanine transport +namespace: biological_process +def: "The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:hjd] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0001763 +name: morphogenesis of a branching structure +namespace: biological_process +def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544] +synonym: "branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0001764 +name: neuron migration +namespace: biological_process +def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators] +synonym: "neuron chemotaxis" EXACT [] +synonym: "neuron guidance" RELATED [] +synonym: "neuronal migration" EXACT [] +xref: Wikipedia:Neural_development#Neuron_migration +xref: Wikipedia:Neuron_migration +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0048699 ! generation of neurons + +[Term] +id: GO:0001765 +name: membrane raft assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes." [PMID:12648772, PMID:12803918, PMID:16645198] +synonym: "lipid raft assembly" EXACT [GOC:mah] +synonym: "lipid raft formation" RELATED [] +synonym: "membrane raft formation" RELATED [GOC:mah] +is_a: GO:0031579 ! membrane raft organization +is_a: GO:0071709 ! membrane assembly + +[Term] +id: GO:0001766 +name: membrane raft polarization +namespace: biological_process +def: "The clustering and aggregation of membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes." [PMID:12615889] +synonym: "lipid raft polarization" EXACT [] +is_a: GO:0031580 ! membrane raft distribution + +[Term] +id: GO:0001767 +name: establishment of lymphocyte polarity +namespace: biological_process +def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] +synonym: "lymphocyte polarization" EXACT [] +is_a: GO:0030010 ! establishment of cell polarity +relationship: part_of GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0001768 +name: establishment of T cell polarity +namespace: biological_process +def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] +synonym: "establishment of T lymphocyte polarity" EXACT [] +synonym: "establishment of T-cell polarity" EXACT [] +synonym: "establishment of T-lymphocyte polarity" EXACT [] +synonym: "T cell polarization" EXACT [] +synonym: "T lymphocyte polarization" EXACT [] +synonym: "T-cell polarization" EXACT [] +is_a: GO:0001767 ! establishment of lymphocyte polarity +relationship: part_of GO:0042110 ! T cell activation + +[Term] +id: GO:0001769 +name: establishment of B cell polarity +namespace: biological_process +def: "The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell." [GOC:mgi_curators, PMID:12615889, PMID:9692889] +comment: Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells. +synonym: "B cell polarization" EXACT [] +synonym: "B lymphocyte polarization" EXACT [] +synonym: "B-cell polarization" EXACT [] +synonym: "establishment of B lymphocyte polarity" EXACT [] +synonym: "establishment of B-cell polarity" EXACT [] +synonym: "establishment of B-lymphocyte polarity" EXACT [] +is_a: GO:0001767 ! establishment of lymphocyte polarity +relationship: part_of GO:0042113 ! B cell activation + +[Term] +id: GO:0001770 +name: establishment of natural killer cell polarity +namespace: biological_process +def: "The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands." [GOC:mgi_curators, PMID:12615886, PMID:9759849] +synonym: "establishment of NK cell polarity" EXACT [] +synonym: "natural killer cell polarization" EXACT [] +synonym: "NK cell polarization" EXACT [] +is_a: GO:0001767 ! establishment of lymphocyte polarity +relationship: part_of GO:0030101 ! natural killer cell activation + +[Term] +id: GO:0001771 +name: immunological synapse formation +namespace: biological_process +def: "The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction." [GOC:mgi_curators, PMID:11244041, PMID:11376330] +synonym: "formation of immunological synapse" EXACT [] +is_a: GO:0009988 ! cell-cell recognition +relationship: part_of GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0001772 +name: immunological synapse +namespace: cellular_component +def: "An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction." [GOC:mgi_curators, PMID:11244041, PMID:11376300] +synonym: "c-SMAC" NARROW [PMID:14724296] +synonym: "supramolecular activation cluster" EXACT [PMID:14724296] +xref: Wikipedia:Immunological_synapse +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0001773 +name: myeloid dendritic cell activation +namespace: biological_process +def: "The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] +is_a: GO:0002274 ! myeloid leukocyte activation + +[Term] +id: GO:0001774 +name: microglial cell activation +namespace: biological_process +def: "The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, PMID:10626665, PMID:10695728, PMID:12580336, PMID:9893949] +is_a: GO:0002269 ! leukocyte activation involved in inflammatory response +is_a: GO:0042116 ! macrophage activation +is_a: GO:0061900 ! glial cell activation + +[Term] +id: GO:0001775 +name: cell activation +namespace: biological_process +def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:mgi_curators] +subset: goslim_pir +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0001776 +name: leukocyte homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149] +comment: Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus. +synonym: "immune cell homeostasis" EXACT [] +synonym: "leucocyte homeostasis" EXACT [] +is_a: GO:0002376 ! immune system process +is_a: GO:0048872 ! homeostasis of number of cells + +[Term] +id: GO:0001777 +name: T cell homeostatic proliferation +namespace: biological_process +def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149] +synonym: "resting T cell proliferation" EXACT [] +synonym: "resting T-cell proliferation" EXACT [] +synonym: "T lymphocyte homeostatic proliferation" EXACT [] +synonym: "T-cell homeostatic proliferation" EXACT [] +synonym: "T-lymphocyte homeostatic proliferation" EXACT [] +is_a: GO:0042098 ! T cell proliferation +relationship: part_of GO:0043029 ! T cell homeostasis + +[Term] +id: GO:0001778 +name: plasma membrane repair +namespace: biological_process +def: "The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress." [GOC:add, PMID:12925704] +is_a: GO:0007009 ! plasma membrane organization +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0001779 +name: natural killer cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "natural killer cell development" RELATED [GOC:add] +synonym: "NK cell differentiation" EXACT [] +is_a: GO:0030098 ! lymphocyte differentiation +is_a: GO:0030101 ! natural killer cell activation + +[Term] +id: GO:0001780 +name: neutrophil homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, GOC:pr, PMID:12752675, PMID:12960266] +comment: Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus. +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis + +[Term] +id: GO:0001781 +name: neutrophil apoptotic process +namespace: biological_process +def: "Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [CL:0000775, GOC:add, GOC:mtg_apoptosis, PMID:12752675, PMID:12960266] +synonym: "apoptosis of neutrophils" EXACT [] +synonym: "neutrophil apoptosis" NARROW [] +synonym: "neutrophil programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of neutrophils by apoptosis" EXACT [] +synonym: "programmed cell death, neutrophils" EXACT [] +is_a: GO:0006925 ! inflammatory cell apoptotic process +is_a: GO:0033028 ! myeloid cell apoptotic process +is_a: GO:0071887 ! leukocyte apoptotic process +relationship: part_of GO:0001780 ! neutrophil homeostasis + +[Term] +id: GO:0001782 +name: B cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149, PMID:12956429] +comment: Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus. +synonym: "B lymphocyte homeostasis" EXACT [] +synonym: "B-cell homeostasis" EXACT [] +synonym: "B-lymphocyte homeostasis" EXACT [] +is_a: GO:0002260 ! lymphocyte homeostasis + +[Term] +id: GO:0001783 +name: B cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity." [CL:0000236, GOC:add, GOC:mtg_apoptosis, ISBN:0781735149] +synonym: "apoptosis of B cells" EXACT [] +synonym: "apoptosis of B lymphocytes" EXACT [] +synonym: "apoptosis of B-cells" EXACT [] +synonym: "apoptosis of B-lymphocytes" EXACT [] +synonym: "B cell apoptosis" NARROW [] +synonym: "B cell programmed cell death by apoptosis" EXACT [] +synonym: "B lymphocyte apoptosis" EXACT [] +synonym: "B lymphocyte programmed cell death by apoptosis" EXACT [] +synonym: "B-cell apoptosis" EXACT [] +synonym: "B-cell programmed cell death by apoptosis" EXACT [] +synonym: "B-lymphocyte apoptosis" EXACT [] +synonym: "B-lymphocyte programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of B cells by apoptosis" EXACT [] +synonym: "programmed cell death of B lymphocytes by apoptosis" EXACT [] +synonym: "programmed cell death of B-cells by apoptosis" EXACT [] +synonym: "programmed cell death of B-lymphocytes by apoptosis" EXACT [] +synonym: "programmed cell death, B cells" EXACT [] +synonym: "programmed cell death, B lymphocytes" EXACT [] +synonym: "programmed cell death, B-cells" EXACT [] +synonym: "programmed cell death, B-lymphocytes" EXACT [] +is_a: GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0001784 +name: phosphotyrosine residue binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein." [PMID:14636584] +synonym: "phosphotyrosine binding" RELATED [] +is_a: GO:0045309 ! protein phosphorylated amino acid binding + +[Term] +id: GO:0001785 +name: prostaglandin J receptor activity +namespace: molecular_function +def: "Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity." [PMID:12878180] +synonym: "PGJ receptor activity" RELATED [] +synonym: "PGJ(2) receptor activity" EXACT [] +is_a: GO:0004955 ! prostaglandin receptor activity + +[Term] +id: GO:0001786 +name: phosphatidylserine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine." [ISBN:0198506732, PMID:12000961] +is_a: GO:0005543 ! phospholipid binding +is_a: GO:0072341 ! modified amino acid binding + +[Term] +id: GO:0001787 +name: natural killer cell proliferation +namespace: biological_process +def: "The expansion of a natural killer cell population by cell division." [GOC:add, ISBN:0781735149] +synonym: "NK cell proliferation" EXACT [] +is_a: GO:0030101 ! natural killer cell activation +is_a: GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0001788 +name: antibody-dependent cellular cytotoxicity +namespace: biological_process +def: "Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells." [GOC:pr, ISBN:0781735149, PMID:11677095, PMID:9581795] +synonym: "ADCC" EXACT [] +synonym: "antibody dependent cell death" EXACT [] +synonym: "antibody dependent cell killing" EXACT [] +synonym: "antibody-dependent cell death" EXACT [] +synonym: "antibody-dependent cell killing" EXACT [] +synonym: "type VI hypersensitivity" EXACT [] +xref: Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity +xref: Wikipedia:Antibody-dependent_cellular_cytotoxicity +is_a: GO:0001794 ! type IIa hypersensitivity +is_a: GO:0001909 ! leukocyte mediated cytotoxicity + +[Term] +id: GO:0001790 +name: polymeric immunoglobulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes." [GOC:add, ISBN:0781735149] +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0001791 +name: IgM binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin of the IgM isotype." [GOC:add, ISBN:0781735149] +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0001792 +name: polymeric immunoglobulin receptor activity +namespace: molecular_function +def: "Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0019763 ! immunoglobulin receptor activity +relationship: has_part GO:0001790 ! polymeric immunoglobulin binding + +[Term] +id: GO:0001793 +name: IgM receptor activity +namespace: molecular_function +def: "Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0019763 ! immunoglobulin receptor activity +relationship: has_part GO:0001791 ! IgM binding + +[Term] +id: GO:0001794 +name: type IIa hypersensitivity +namespace: biological_process +def: "An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell." [GOC:add, ISBN:0781735149] +comment: Note that some type IIb hypersensitivity responses (GO:0001795) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIa hypersensitivity. +is_a: GO:0002445 ! type II hypersensitivity + +[Term] +id: GO:0001795 +name: type IIb hypersensitivity +namespace: biological_process +def: "An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors." [GOC:add, ISBN:0781735149] +comment: Note that some type IIa hypersensitivity response (GO:0001794) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIb hypersensitivity. +synonym: "type V hypersensitivity" EXACT [] +is_a: GO:0002445 ! type II hypersensitivity + +[Term] +id: GO:0001796 +name: regulation of type IIa hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +is_a: GO:0002892 ! regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001794 ! type IIa hypersensitivity +relationship: regulates GO:0001794 ! type IIa hypersensitivity + +[Term] +id: GO:0001797 +name: negative regulation of type IIa hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "down regulation of type IIa hypersensitivity" EXACT [] +synonym: "down-regulation of type IIa hypersensitivity" EXACT [] +synonym: "downregulation of type IIa hypersensitivity" EXACT [] +synonym: "inhibition of type IIa hypersensitivity" NARROW [] +is_a: GO:0001796 ! regulation of type IIa hypersensitivity +is_a: GO:0002893 ! negative regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001794 ! type IIa hypersensitivity +relationship: negatively_regulates GO:0001794 ! type IIa hypersensitivity + +[Term] +id: GO:0001798 +name: positive regulation of type IIa hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "activation of type IIa hypersensitivity" NARROW [] +synonym: "stimulation of type IIa hypersensitivity" NARROW [] +synonym: "up regulation of type IIa hypersensitivity" EXACT [] +synonym: "up-regulation of type IIa hypersensitivity" EXACT [] +synonym: "upregulation of type IIa hypersensitivity" EXACT [] +is_a: GO:0001796 ! regulation of type IIa hypersensitivity +is_a: GO:0002894 ! positive regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001794 ! type IIa hypersensitivity +relationship: positively_regulates GO:0001794 ! type IIa hypersensitivity + +[Term] +id: GO:0001799 +name: regulation of type IIb hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +is_a: GO:0002892 ! regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001795 ! type IIb hypersensitivity +relationship: regulates GO:0001795 ! type IIb hypersensitivity + +[Term] +id: GO:0001800 +name: negative regulation of type IIb hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "down regulation of type IIb hypersensitivity" EXACT [] +synonym: "down-regulation of type IIb hypersensitivity" EXACT [] +synonym: "downregulation of type IIb hypersensitivity" EXACT [] +synonym: "inhibition of type IIb hypersensitivity" NARROW [] +is_a: GO:0001799 ! regulation of type IIb hypersensitivity +is_a: GO:0002893 ! negative regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001795 ! type IIb hypersensitivity +relationship: negatively_regulates GO:0001795 ! type IIb hypersensitivity + +[Term] +id: GO:0001801 +name: positive regulation of type IIb hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "activation of type IIb hypersensitivity" NARROW [] +synonym: "stimulation of type IIb hypersensitivity" NARROW [] +synonym: "up regulation of type IIb hypersensitivity" EXACT [] +synonym: "up-regulation of type IIb hypersensitivity" EXACT [] +synonym: "upregulation of type IIb hypersensitivity" EXACT [] +is_a: GO:0001799 ! regulation of type IIb hypersensitivity +is_a: GO:0002894 ! positive regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001795 ! type IIb hypersensitivity +relationship: positively_regulates GO:0001795 ! type IIb hypersensitivity + +[Term] +id: GO:0001802 +name: type III hypersensitivity +namespace: biological_process +def: "An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue." [GOC:add, ISBN:0781735149] +comment: Note that the Arthus reaction is an example of type III hypersensitivity. +xref: Wikipedia:Type_III_hypersensitivity +is_a: GO:0002444 ! myeloid leukocyte mediated immunity +is_a: GO:0002524 ! hypersensitivity +is_a: GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0001803 +name: regulation of type III hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +is_a: GO:0002883 ! regulation of hypersensitivity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001802 ! type III hypersensitivity +relationship: regulates GO:0001802 ! type III hypersensitivity + +[Term] +id: GO:0001804 +name: negative regulation of type III hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "down regulation of type III hypersensitivity" EXACT [] +synonym: "down-regulation of type III hypersensitivity" EXACT [] +synonym: "downregulation of type III hypersensitivity" EXACT [] +synonym: "inhibition of type III hypersensitivity" NARROW [] +is_a: GO:0001803 ! regulation of type III hypersensitivity +is_a: GO:0002884 ! negative regulation of hypersensitivity +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0002890 ! negative regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001802 ! type III hypersensitivity +relationship: negatively_regulates GO:0001802 ! type III hypersensitivity + +[Term] +id: GO:0001805 +name: positive regulation of type III hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "activation of type III hypersensitivity" NARROW [] +synonym: "stimulation of type III hypersensitivity" NARROW [] +synonym: "up regulation of type III hypersensitivity" EXACT [] +synonym: "up-regulation of type III hypersensitivity" EXACT [] +synonym: "upregulation of type III hypersensitivity" EXACT [] +is_a: GO:0001803 ! regulation of type III hypersensitivity +is_a: GO:0002885 ! positive regulation of hypersensitivity +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001802 ! type III hypersensitivity +relationship: positively_regulates GO:0001802 ! type III hypersensitivity + +[Term] +id: GO:0001806 +name: type IV hypersensitivity +namespace: biological_process +alt_id: GO:0016069 +def: "An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation." [GOC:add, ISBN:0781735149] +synonym: "delayed hypersensitivity response" EXACT [] +synonym: "delayed-type hypersensitivity" EXACT [] +xref: Wikipedia:Type_IV_hypersensitivity +is_a: GO:0002456 ! T cell mediated immunity +is_a: GO:0002524 ! hypersensitivity + +[Term] +id: GO:0001807 +name: regulation of type IV hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +is_a: GO:0002709 ! regulation of T cell mediated immunity +is_a: GO:0002883 ! regulation of hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001806 ! type IV hypersensitivity +relationship: regulates GO:0001806 ! type IV hypersensitivity + +[Term] +id: GO:0001808 +name: negative regulation of type IV hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "down regulation of type IV hypersensitivity" EXACT [] +synonym: "down-regulation of type IV hypersensitivity" EXACT [] +synonym: "downregulation of type IV hypersensitivity" EXACT [] +synonym: "inhibition of type IV hypersensitivity" NARROW [] +is_a: GO:0001807 ! regulation of type IV hypersensitivity +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +is_a: GO:0002884 ! negative regulation of hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001806 ! type IV hypersensitivity +relationship: negatively_regulates GO:0001806 ! type IV hypersensitivity + +[Term] +id: GO:0001809 +name: positive regulation of type IV hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "activation of type IV hypersensitivity" NARROW [] +synonym: "stimulation of type IV hypersensitivity" NARROW [] +synonym: "up regulation of type IV hypersensitivity" EXACT [] +synonym: "up-regulation of type IV hypersensitivity" EXACT [] +synonym: "upregulation of type IV hypersensitivity" EXACT [] +is_a: GO:0001807 ! regulation of type IV hypersensitivity +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +is_a: GO:0002885 ! positive regulation of hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001806 ! type IV hypersensitivity +relationship: positively_regulates GO:0001806 ! type IV hypersensitivity + +[Term] +id: GO:0001810 +name: regulation of type I hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response." [ISBN:0781735149] +is_a: GO:0002883 ! regulation of hypersensitivity +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016068 ! type I hypersensitivity +relationship: regulates GO:0016068 ! type I hypersensitivity + +[Term] +id: GO:0001811 +name: negative regulation of type I hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "down regulation of type I hypersensitivity" EXACT [] +synonym: "down-regulation of type I hypersensitivity" EXACT [] +synonym: "downregulation of type I hypersensitivity" EXACT [] +synonym: "inhibition of type I hypersensitivity" NARROW [] +is_a: GO:0001810 ! regulation of type I hypersensitivity +is_a: GO:0002884 ! negative regulation of hypersensitivity +is_a: GO:0002890 ! negative regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016068 ! type I hypersensitivity +relationship: negatively_regulates GO:0016068 ! type I hypersensitivity + +[Term] +id: GO:0001812 +name: positive regulation of type I hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "activation of type I hypersensitivity" NARROW [] +synonym: "stimulation of type I hypersensitivity" NARROW [] +synonym: "up regulation of type I hypersensitivity" EXACT [] +synonym: "up-regulation of type I hypersensitivity" EXACT [] +synonym: "upregulation of type I hypersensitivity" EXACT [] +is_a: GO:0001810 ! regulation of type I hypersensitivity +is_a: GO:0002885 ! positive regulation of hypersensitivity +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016068 ! type I hypersensitivity +relationship: positively_regulates GO:0016068 ! type I hypersensitivity + +[Term] +id: GO:0001813 +name: regulation of antibody-dependent cellular cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "regulation of antibody dependent cell death" EXACT [] +synonym: "regulation of antibody dependent cell killing" EXACT [] +synonym: "regulation of antibody-dependent cell death" EXACT [] +synonym: "regulation of antibody-dependent cell killing" EXACT [] +is_a: GO:0001796 ! regulation of type IIa hypersensitivity +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001788 ! antibody-dependent cellular cytotoxicity +relationship: regulates GO:0001788 ! antibody-dependent cellular cytotoxicity + +[Term] +id: GO:0001814 +name: negative regulation of antibody-dependent cellular cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "down regulation of antibody-dependent cellular cytotoxicity" EXACT [] +synonym: "down-regulation of antibody-dependent cellular cytotoxicity" EXACT [] +synonym: "downregulation of antibody-dependent cellular cytotoxicity" EXACT [] +synonym: "inhibition of antibody-dependent cellular cytotoxicity" NARROW [] +synonym: "negative regulation of antibody dependent cell death" EXACT [] +synonym: "negative regulation of antibody dependent cell killing" EXACT [] +synonym: "negative regulation of antibody-dependent cell death" EXACT [] +synonym: "negative regulation of antibody-dependent cell killing" EXACT [] +is_a: GO:0001797 ! negative regulation of type IIa hypersensitivity +is_a: GO:0001813 ! regulation of antibody-dependent cellular cytotoxicity +is_a: GO:0001911 ! negative regulation of leukocyte mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001788 ! antibody-dependent cellular cytotoxicity +relationship: negatively_regulates GO:0001788 ! antibody-dependent cellular cytotoxicity + +[Term] +id: GO:0001815 +name: positive regulation of antibody-dependent cellular cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "activation of antibody-dependent cellular cytotoxicity" NARROW [] +synonym: "positive regulation of antibody dependent cell death" EXACT [] +synonym: "positive regulation of antibody dependent cell killing" EXACT [] +synonym: "positive regulation of antibody-dependent cell death" EXACT [] +synonym: "positive regulation of antibody-dependent cell killing" EXACT [] +synonym: "stimulation of antibody-dependent cellular cytotoxicity" NARROW [] +synonym: "up regulation of antibody-dependent cellular cytotoxicity" EXACT [] +synonym: "up-regulation of antibody-dependent cellular cytotoxicity" EXACT [] +synonym: "upregulation of antibody-dependent cellular cytotoxicity" EXACT [] +is_a: GO:0001798 ! positive regulation of type IIa hypersensitivity +is_a: GO:0001813 ! regulation of antibody-dependent cellular cytotoxicity +is_a: GO:0001912 ! positive regulation of leukocyte mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001788 ! antibody-dependent cellular cytotoxicity +relationship: positively_regulates GO:0001788 ! antibody-dependent cellular cytotoxicity + +[Term] +id: GO:0001816 +name: cytokine production +namespace: biological_process +def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +comment: Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular cytokine levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting cytokine molecules, or increased conversion from precursor molecules. +subset: goslim_pir +synonym: "interferon production" NARROW [GOC:add, GOC:mah] +synonym: "interleukin production" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] +is_a: GO:0010467 ! gene expression +is_a: GO:0032501 ! multicellular organismal process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19116 xsd:anyURI + +[Term] +id: GO:0001817 +name: regulation of cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001816 ! cytokine production +relationship: regulates GO:0001816 ! cytokine production + +[Term] +id: GO:0001818 +name: negative regulation of cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149] +synonym: "down regulation of cytokine production" EXACT [] +synonym: "down-regulation of cytokine production" EXACT [] +synonym: "downregulation of cytokine production" EXACT [] +synonym: "inhibition of cytokine production" NARROW [] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001816 ! cytokine production +relationship: negatively_regulates GO:0001816 ! cytokine production + +[Term] +id: GO:0001819 +name: positive regulation of cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149] +synonym: "activation of cytokine production" NARROW [] +synonym: "stimulation of cytokine production" NARROW [] +synonym: "up regulation of cytokine production" EXACT [] +synonym: "up-regulation of cytokine production" EXACT [] +synonym: "upregulation of cytokine production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001816 ! cytokine production +relationship: positively_regulates GO:0001816 ! cytokine production + +[Term] +id: GO:0001820 +name: serotonin secretion +namespace: biological_process +def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149] +synonym: "5-HT secretion" EXACT [] +synonym: "5-hydroxytryptamine secretion" EXACT [] +synonym: "serotonin release" RELATED [GOC:tb] +is_a: GO:0006837 ! serotonin transport +is_a: GO:0023061 ! signal release + +[Term] +id: GO:0001821 +name: histamine secretion +namespace: biological_process +def: "The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems." [GOC:mah, ISBN:0198506732, ISBN:0781735149] +is_a: GO:0046903 ! secretion +is_a: GO:0051608 ! histamine transport + +[Term] +id: GO:0001822 +name: kidney development +namespace: biological_process +def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544] +synonym: "nephrogenesis" RELATED [GOC:rph] +xref: Wikipedia:Kidney_development +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0072001 ! renal system development + +[Term] +id: GO:0001823 +name: mesonephros development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314] +synonym: "Wolffian body development" EXACT [GOC:dph] +is_a: GO:0001822 ! kidney development + +[Term] +id: GO:0001824 +name: blastocyst development +namespace: biological_process +def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001701 ! in utero embryonic development + +[Term] +id: GO:0001825 +name: blastocyst formation +namespace: biological_process +def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0001824 ! blastocyst development + +[Term] +id: GO:0001826 +name: inner cell mass cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'. +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001825 ! blastocyst formation + +[Term] +id: GO:0001827 +name: inner cell mass cell fate commitment +namespace: biological_process +def: "The cell fate commitment of precursor cells that will become inner cell mass cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, compacted morula ; EMAP:13' and 'TS4, inner cell mass ; EMAP:14'. +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0001826 ! inner cell mass cell differentiation + +[Term] +id: GO:0001828 +name: inner cell mass cellular morphogenesis +namespace: biological_process +def: "The morphogenesis of cells in the inner cell mass." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001826 ! inner cell mass cell differentiation + +[Term] +id: GO:0001829 +name: trophectodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. +synonym: "trophectoderm cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001825 ! blastocyst formation + +[Term] +id: GO:0001830 +name: trophectodermal cell fate commitment +namespace: biological_process +def: "The cell fate commitment of precursor cells that will become trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. +synonym: "trophectoderm cell fate commitment" EXACT [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0001829 ! trophectodermal cell differentiation + +[Term] +id: GO:0001831 +name: trophectodermal cellular morphogenesis +namespace: biological_process +def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. +synonym: "trophectoderm cellular morphogenesis" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001829 ! trophectodermal cell differentiation + +[Term] +id: GO:0001832 +name: blastocyst growth +namespace: biological_process +def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0001824 ! blastocyst development + +[Term] +id: GO:0001833 +name: inner cell mass cell proliferation +namespace: biological_process +def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. +is_a: GO:0008283 ! cell population proliferation +relationship: part_of GO:0001832 ! blastocyst growth + +[Term] +id: GO:0001834 +name: trophectodermal cell proliferation +namespace: biological_process +def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. +synonym: "trophectoderm cell proliferation" EXACT [] +is_a: GO:0008283 ! cell population proliferation +relationship: part_of GO:0001832 ! blastocyst growth + +[Term] +id: GO:0001835 +name: blastocyst hatching +namespace: biological_process +def: "The hatching of the cellular blastocyst from the zona pellucida." [GOC:dph, ISBN:0124020607, ISBN:0198542771] +comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, zona pellucida ; EMAP:22' and 'TS5, embryo ; EMAP:23'. +is_a: GO:0035188 ! hatching +relationship: part_of GO:0001824 ! blastocyst development + +[Term] +id: GO:0001836 +name: release of cytochrome c from mitochondria +namespace: biological_process +def: "The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation." [GOC:add, GOC:mah, GOC:mtg_apoptosis, ISBN:0721639976, PMID:12925707, PMID:9560217] +comment: The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that are directly involved in this process. An example is Drp1 (DNM1L, UniProt symbol O00429) in PMID:20850011. +is_a: GO:0008637 ! apoptotic mitochondrial changes +relationship: part_of GO:0097190 ! apoptotic signaling pathway + +[Term] +id: GO:0001837 +name: epithelial to mesenchymal transition +namespace: biological_process +def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] +synonym: "EMT" EXACT [] +synonym: "epithelial-mesenchymal transition" EXACT [] +synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] +is_a: GO:0048762 ! mesenchymal cell differentiation + +[Term] +id: GO:0001838 +name: embryonic epithelial tube formation +namespace: biological_process +def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820] +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium + +[Term] +id: GO:0001839 +name: neural plate morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0001840 ! neural plate development + +[Term] +id: GO:0001840 +name: neural plate development +namespace: biological_process +def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0001841 +name: neural tube formation +namespace: biological_process +alt_id: GO:0001679 +def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437] +synonym: "neural tube morphogenesis" EXACT [GOC:dph] +synonym: "neurulation" EXACT [] +xref: Wikipedia:Neurulation +is_a: GO:0001838 ! embryonic epithelial tube formation +relationship: part_of GO:0021915 ! neural tube development + +[Term] +id: GO:0001842 +name: neural fold formation +namespace: biological_process +def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437] +synonym: "neural groove formation" RELATED [GOC:dph] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0014020 ! primary neural tube formation + +[Term] +id: GO:0001843 +name: neural tube closure +namespace: biological_process +def: "The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline." [GOC:dph, ISBN:0878932437] +is_a: GO:0060606 ! tube closure +relationship: part_of GO:0014020 ! primary neural tube formation + +[Term] +id: GO:0001844 +name: protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +namespace: biological_process +def: "The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway." [GOC:add, GOC:mtg_apoptosis, PMID:12952892] +comment: Note that this term is intended to cover the insertion of pro-apoptotic proteins such as Bax or its homologs into mitochondrial membranes which occurs as an early step in the apoptotic program. +synonym: "insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [] +synonym: "protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:dph, GOC:tb] +synonym: "protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [] +synonym: "protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [] +is_a: GO:0051204 ! protein insertion into mitochondrial membrane +intersection_of: GO:0051204 ! protein insertion into mitochondrial membrane +intersection_of: part_of GO:0097190 ! apoptotic signaling pathway +relationship: part_of GO:0097345 ! mitochondrial outer membrane permeabilization + +[Term] +id: GO:0001845 +name: phagolysosome assembly +namespace: biological_process +def: "The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome." [GOC:add, ISBN:0781735149] +synonym: "late phagosome biosynthesis" RELATED [] +synonym: "late phagosome formation" RELATED [] +synonym: "phagolysosome formation" RELATED [GOC:mah] +is_a: GO:0007040 ! lysosome organization +is_a: GO:0016050 ! vesicle organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0006909 ! phagocytosis +relationship: part_of GO:0090382 ! phagosome maturation + +[Term] +id: GO:0001846 +name: opsonin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material." [GOC:add, ISBN:0781735149] +comment: Note that an opsonin is a blood serum protein or fragment which when deposited on the surface of a bacteria, virus, immune complex, or other particulate material acts a signal for phagocytosis to cells bearing the appropriate receptors. Not all complement components or fragments and not all antibodies have opsonic properties. +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0001847 +name: opsonin receptor activity +namespace: molecular_function +def: "Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0001846 ! opsonin binding + +[Term] +id: GO:0001848 +name: complement binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any component or product of the complement cascade." [GOC:add, ISBN:0781735149] +comment: Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways. +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0001849 +name: complement component C1q complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C1q complex, a component of the classical complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001846 ! opsonin binding +is_a: GO:0001848 ! complement binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0001850 +name: complement component C3a binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C3a product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001851 +name: complement component C3b binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C3b product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001846 ! opsonin binding +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001852 +name: complement component iC3b binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the iC3b product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001846 ! opsonin binding +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001853 +name: complement component C3dg binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C3dg product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001854 +name: complement component C3d binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C3d product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001855 +name: complement component C4b binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C4b product of the classical complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001846 ! opsonin binding +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001856 +name: complement component C5a binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C5a product of the complement cascade." [GOC:add, ISBN:0781735149] +is_a: GO:0001848 ! complement binding + +[Term] +id: GO:0001857 +name: complement component C1q receptor activity +namespace: molecular_function +def: "Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0001847 ! opsonin receptor activity +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001849 ! complement component C1q complex binding + +[Term] +id: GO:0001858 +name: complement component iC3b receptor activity +namespace: molecular_function +def: "Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0001847 ! opsonin receptor activity +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001852 ! complement component iC3b binding + +[Term] +id: GO:0001859 +name: complement component C3dg receptor activity +namespace: molecular_function +def: "Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001853 ! complement component C3dg binding + +[Term] +id: GO:0001860 +name: complement component C3d receptor activity +namespace: molecular_function +def: "Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001854 ! complement component C3d binding + +[Term] +id: GO:0001861 +name: complement component C4b receptor activity +namespace: molecular_function +def: "Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0001847 ! opsonin receptor activity +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001855 ! complement component C4b binding + +[Term] +id: GO:0001862 +name: collectin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus." [GOC:add, ISBN:0781735149] +comment: Note that collectins include such proteins as mannose-binding lectins (MBL) and surfactant proteins A and D (SP-A and SP-D). +is_a: GO:0001846 ! opsonin binding + +[Term] +id: GO:0001863 +name: collectin receptor activity +namespace: molecular_function +def: "Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +comment: Note that collectins include such proteins as mannose-binding lectin (MBL) and surfactant proteins A and D (SP-A and SP-D). +is_a: GO:0001847 ! opsonin receptor activity +relationship: has_part GO:0001862 ! collectin binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0001864 +name: pentraxin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array." [GOC:add, ISBN:0781735149] +comment: Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP). +is_a: GO:0001846 ! opsonin binding + +[Term] +id: GO:0001865 +name: NK T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a NK T cell." [GOC:add, ISBN:0781735149, PMID:10704459] +comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "natural killer T cell differentiation" EXACT [] +synonym: "natural T cell differentiation" EXACT [] +synonym: "NK T cell development" RELATED [GOC:add] +synonym: "NK T lymphocyte differentiation" EXACT [] +synonym: "NK T-cell differentiation" EXACT [] +synonym: "NK T-lymphocyte differentiation" EXACT [] +synonym: "NKT cell differentiation" EXACT [] +synonym: "NT cell differentiation" EXACT [] +is_a: GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0001866 +name: NK T cell proliferation +namespace: biological_process +def: "The expansion of a NK T cell population by cell division." [GOC:add, ISBN:0781735149, PMID:10704459] +comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. +synonym: "natural killer T cell proliferation" EXACT [] +synonym: "natural T cell proliferation" EXACT [] +synonym: "NK T lymphocyte proliferation" EXACT [] +synonym: "NK T-cell proliferation" EXACT [] +synonym: "NK T-lymphocyte proliferation" EXACT [] +synonym: "NKT cell proliferation" EXACT [] +synonym: "NT cell proliferation" EXACT [] +is_a: GO:0046633 ! alpha-beta T cell proliferation +is_a: GO:0051132 ! NK T cell activation + +[Term] +id: GO:0001867 +name: complement activation, lectin pathway +namespace: biological_process +def: "Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes." [GOC:add, ISBN:0781735149] +comment: Note that proteins such as mannose-binding lectin (MBL) and certain serum ficolins can activate the lectin complement pathway. +synonym: "complement cascade, lectin pathway" EXACT [GOC:add] +is_a: GO:0006956 ! complement activation +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0001868 +name: regulation of complement activation, lectin pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation." [GOC:add, ISBN:0781735149] +synonym: "regulation of complement cascade, lectin pathway" EXACT [GOC:add] +is_a: GO:0030449 ! regulation of complement activation +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001867 ! complement activation, lectin pathway +relationship: regulates GO:0001867 ! complement activation, lectin pathway + +[Term] +id: GO:0001869 +name: negative regulation of complement activation, lectin pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway." [GOC:add, ISBN:0781735149] +synonym: "down regulation of complement activation, lectin pathway" EXACT [] +synonym: "down-regulation of complement activation, lectin pathway" EXACT [] +synonym: "downregulation of complement activation, lectin pathway" EXACT [] +synonym: "inhibition of complement activation, lectin pathway" NARROW [] +synonym: "negative regulation of complement cascade, lectin pathway" EXACT [GOC:add] +is_a: GO:0001868 ! regulation of complement activation, lectin pathway +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0045916 ! negative regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001867 ! complement activation, lectin pathway +relationship: negatively_regulates GO:0001867 ! complement activation, lectin pathway + +[Term] +id: GO:0001870 +name: positive regulation of complement activation, lectin pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway." [GOC:add, ISBN:0781735149] +synonym: "activation of complement activation, lectin pathway" NARROW [] +synonym: "positive regulation of complement cascade, lectin pathway" EXACT [GOC:add] +synonym: "stimulation of complement activation, lectin pathway" NARROW [] +synonym: "up regulation of complement activation, lectin pathway" EXACT [] +synonym: "up-regulation of complement activation, lectin pathway" EXACT [] +synonym: "upregulation of complement activation, lectin pathway" EXACT [] +is_a: GO:0001868 ! regulation of complement activation, lectin pathway +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0045917 ! positive regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001867 ! complement activation, lectin pathway +relationship: positively_regulates GO:0001867 ! complement activation, lectin pathway + +[Term] +id: GO:0001871 +name: obsolete pattern binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan." [PMID:12072369, PMID:12225919, PMID:12507420, PMID:12925128, PMID:14523544] +comment: This term was obsoleted because it was an unnecessary grouping term. +synonym: "pattern recognition activity" BROAD [] +is_obsolete: true + +[Term] +id: GO:0001872 +name: (1->3)-beta-D-glucan binding +namespace: molecular_function +alt_id: GO:0080087 +def: "Interacting selectively and non-covalently with (1->3)-beta-D-glucans." [PMID:14707091] +synonym: "1,3-beta-D-glucan binding" EXACT [] +synonym: "callose binding" NARROW [] +synonym: "zymosan binding" NARROW [GOC:tb] +is_a: GO:0030247 ! polysaccharide binding + +[Term] +id: GO:0001873 +name: polysaccharide immune receptor activity +namespace: molecular_function +def: "Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:14707091] +synonym: "polysaccharide receptor activity" BROAD [] +is_a: GO:0038187 ! pattern recognition receptor activity +relationship: has_part GO:0030247 ! polysaccharide binding + +[Term] +id: GO:0001874 +name: (1->3)-beta-D-glucan immune receptor activity +namespace: molecular_function +def: "Combining with (1->3)-beta-D-glucans to initiate an innate immune response." [PMID:14707091] +synonym: "(1,3)-beta-D-glucan receptor activity" EXACT [] +synonym: "(1->3)-beta-D-glucan receptor activity" BROAD [] +synonym: "1,3-beta-D-glucan receptor activity" EXACT [] +synonym: "beta-1,3-D-glucan receptor activity" EXACT [] +synonym: "zymosan receptor activity" NARROW [GOC:tb] +is_a: GO:0001873 ! polysaccharide immune receptor activity +relationship: has_part GO:0001872 ! (1->3)-beta-D-glucan binding + +[Term] +id: GO:0001875 +name: lipopolysaccharide immune receptor activity +namespace: molecular_function +def: "Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system." [PMID:14609719, PMID:15379975] +synonym: "endotoxin receptor activity" BROAD [] +synonym: "lipopolysaccharide receptor activity" BROAD [] +synonym: "LPS receptor activity" EXACT [] +is_a: GO:0038187 ! pattern recognition receptor activity +relationship: has_part GO:0001530 ! lipopolysaccharide binding +relationship: part_of GO:0031663 ! lipopolysaccharide-mediated signaling pathway + +[Term] +id: GO:0001876 +name: lipoarabinomannan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipoarabinomannan." [PMID:10586073] +synonym: "LAM binding" EXACT [] +is_a: GO:0034235 ! GPI anchor binding + +[Term] +id: GO:0001877 +name: lipoarabinomannan immune receptor activity +namespace: molecular_function +def: "Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response." [PMID:10586073] +synonym: "LAM receptor activity" EXACT [] +synonym: "lipoarabinomannan receptor activity" BROAD [] +is_a: GO:0038187 ! pattern recognition receptor activity +relationship: has_part GO:0001876 ! lipoarabinomannan binding + +[Term] +id: GO:0001878 +name: response to yeast +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." [PMID:14707091] +comment: defined as response to Saccharomycotina (true yeasts). This excludes fission yeast. +is_a: GO:0009620 ! response to fungus + +[Term] +id: GO:0001879 +name: detection of yeast +namespace: biological_process +def: "The series of events in which a stimulus from a yeast is received and converted into a molecular signal." [PMID:14707091] +is_a: GO:0001878 ! response to yeast +is_a: GO:0016046 ! detection of fungus + +[Term] +id: GO:0001880 +name: Mullerian duct regression +namespace: biological_process +def: "The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos." [GOC:dph, PMID:12368913] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0046661 ! male sex differentiation + +[Term] +id: GO:0001881 +name: receptor recycling +namespace: biological_process +def: "The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal." [GOC:dph] +is_a: GO:0043112 ! receptor metabolic process +relationship: has_part GO:0006897 ! endocytosis + +[Term] +id: GO:0001882 +name: nucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] +subset: goslim_pir +is_a: GO:0036094 ! small molecule binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0097367 ! carbohydrate derivative binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0001883 +name: purine nucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] +is_a: GO:0001882 ! nucleoside binding + +[Term] +id: GO:0001884 +name: pyrimidine nucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose." [GOC:hjd] +is_a: GO:0001882 ! nucleoside binding + +[Term] +id: GO:0001885 +name: endothelial cell development +namespace: biological_process +def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0045446 ! endothelial cell differentiation + +[Term] +id: GO:0001886 +name: endothelial cell morphogenesis +namespace: biological_process +def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003382 ! epithelial cell morphogenesis +relationship: part_of GO:0001885 ! endothelial cell development + +[Term] +id: GO:0001887 +name: selenium compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine." [PMID:12730456] +synonym: "selenium compound metabolism" EXACT [] +synonym: "selenium metabolic process" EXACT [] +synonym: "selenium metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0001888 +name: glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan." [EC:2.4.1.223, RHEA:16221] +synonym: "alpha-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] +synonym: "alpha-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.223] +synonym: "alpha1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] +synonym: "glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.223] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.223] +xref: EC:2.4.1.223 +xref: MetaCyc:2.4.1.223-RXN +xref: RHEA:16221 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0001889 +name: liver development +namespace: biological_process +def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0061008 ! hepaticobiliary system development + +[Term] +id: GO:0001890 +name: placenta development +namespace: biological_process +def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] +synonym: "placental development" EXACT [] +synonym: "placentation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0048513 ! animal organ development +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0001891 +name: phagocytic cup +namespace: cellular_component +def: "An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome." [PMID:10358769] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0001892 +name: embryonic placenta development +namespace: biological_process +def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] +synonym: "fetal placenta development" EXACT [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048568 ! embryonic organ development +relationship: part_of GO:0001701 ! in utero embryonic development +relationship: part_of GO:0001890 ! placenta development + +[Term] +id: GO:0001893 +name: maternal placenta development +namespace: biological_process +def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] +synonym: "decidua development" RELATED [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +is_a: GO:0060135 ! maternal process involved in female pregnancy +relationship: part_of GO:0001890 ! placenta development + +[Term] +id: GO:0001894 +name: tissue homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function." [GOC:add, GOC:isa_complete] +synonym: "tissue maintenance" NARROW [GOC:add] +is_a: GO:0060249 ! anatomical structure homeostasis +relationship: part_of GO:0048871 ! multicellular organismal homeostasis + +[Term] +id: GO:0001895 +name: retina homeostasis +namespace: biological_process +def: "A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function." [GOC:add, GOC:dph, GOC:tb, PMID:15365173, PMID:15365178] +is_a: GO:0001894 ! tissue homeostasis + +[Term] +id: GO:0001896 +name: autolysis +namespace: biological_process +def: "A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation." [GOC:add, GOC:jh2, GOC:mtg_apoptosis, PMID:10974124, PMID:19286987, PMID:26811896] +xref: Wikipedia:Autolysis +is_a: GO:0012501 ! programmed cell death +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0001897 +name: cytolysis by symbiont of host cells +namespace: biological_process +def: "The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add] +synonym: "cytolysis by organism of host cells" EXACT [] +is_a: GO:0001907 ! killing by symbiont of host cells +is_a: GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +relationship: has_part GO:0052025 ! modification by symbiont of host cell membrane + +[Term] +id: GO:0001898 +name: regulation of cytolysis by symbiont of host cells +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation by symbiont of cytolysis of host cells" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0051802 ! regulation of cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001897 ! cytolysis by symbiont of host cells +relationship: regulates GO:0001897 ! cytolysis by symbiont of host cells + +[Term] +id: GO:0001899 +name: negative regulation of cytolysis by symbiont of host cells +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add, GOC:dph, GOC:tb] +synonym: "down regulation by symbiont of cytolysis of host cells" EXACT [] +synonym: "down-regulation by symbiont of cytolysis of host cells" EXACT [] +synonym: "downregulation by symbiont of cytolysis of host cells" EXACT [] +synonym: "inhibition by symbiont of cytolysis of host cells" NARROW [] +synonym: "negative regulation by symbiont of cytolysis of host cells" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001898 ! regulation of cytolysis by symbiont of host cells +is_a: GO:0051803 ! negative regulation of cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001897 ! cytolysis by symbiont of host cells +relationship: negatively_regulates GO:0001897 ! cytolysis by symbiont of host cells + +[Term] +id: GO:0001900 +name: positive regulation of cytolysis by symbiont of host cells +namespace: biological_process +def: "Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add, GOC:dph, GOC:tb] +synonym: "activation by symbiont of cytolysis of host cells" NARROW [] +synonym: "positive regulation by symbiont of cytolysis of host cells" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation by symbiont of cytolysis of host cells" NARROW [] +synonym: "up regulation by symbiont of cytolysis of host cells" EXACT [] +synonym: "up-regulation by symbiont of cytolysis of host cells" EXACT [] +synonym: "upregulation by symbiont of cytolysis of host cells" EXACT [] +is_a: GO:0001898 ! regulation of cytolysis by symbiont of host cells +is_a: GO:0051804 ! positive regulation of cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001897 ! cytolysis by symbiont of host cells +relationship: positively_regulates GO:0001897 ! cytolysis by symbiont of host cells + +[Term] +id: GO:0001905 +name: activation of membrane attack complex +namespace: biological_process +def: "The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis." [GOC:add, ISBN:0781735149] +synonym: "activation of MAC" EXACT [] +synonym: "activation of TCC" NARROW [] +synonym: "activation of terminal complement complex" NARROW [GOC:add] +synonym: "activation of the terminal complement cascade" NARROW [] +synonym: "MAC assembly" EXACT [GOC:rl] +synonym: "MAC formation" EXACT [GOC:rl] +synonym: "membrane attack complex assembly" EXACT [GOC:rl] +synonym: "membrane attack complex formation" EXACT [GOC:rl] +is_a: GO:0006956 ! complement activation + +[Term] +id: GO:0001906 +name: cell killing +namespace: biological_process +def: "Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions." [GOC:add] +subset: goslim_pir +synonym: "necrosis" RELATED [] +is_a: GO:0009987 ! cellular process +disjoint_from: GO:0044848 ! biological phase + +[Term] +id: GO:0001907 +name: killing by symbiont of host cells +namespace: biological_process +def: "Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add] +is_a: GO:0051701 ! interaction with host +is_a: GO:0051883 ! killing of cells in other organism involved in symbiotic interaction + +[Term] +id: GO:0001909 +name: leukocyte mediated cytotoxicity +namespace: biological_process +def: "The directed killing of a target cell by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:11911826] +comment: Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system. +synonym: "immune cell mediated cell death" EXACT [] +synonym: "immune cell mediated cell killing" EXACT [] +synonym: "immune cell mediated cytotoxicity" EXACT [] +synonym: "leucocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001906 ! cell killing +is_a: GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0001910 +name: regulation of leukocyte mediated cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity." [GOC:add, ISBN:0781735149, PMID:11911826] +synonym: "regulation of immune cell mediated cell death" EXACT [] +synonym: "regulation of immune cell mediated cell killing" EXACT [] +synonym: "regulation of immune cell mediated cytotoxicity" EXACT [] +synonym: "regulation of leucocyte mediated cytotoxicity" EXACT [] +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +is_a: GO:0031341 ! regulation of cell killing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001909 ! leukocyte mediated cytotoxicity +relationship: regulates GO:0001909 ! leukocyte mediated cytotoxicity + +[Term] +id: GO:0001911 +name: negative regulation of leukocyte mediated cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity." [GOC:add, ISBN:0781735149, PMID:11911826] +synonym: "down regulation of leukocyte mediated cytotoxicity" EXACT [] +synonym: "down-regulation of leukocyte mediated cytotoxicity" EXACT [] +synonym: "downregulation of leukocyte mediated cytotoxicity" EXACT [] +synonym: "inhibition of leukocyte mediated cytotoxicity" NARROW [] +synonym: "negative regulation of immune cell mediated cytotoxicity" EXACT [] +synonym: "negative regulation of leucocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity +is_a: GO:0031342 ! negative regulation of cell killing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001909 ! leukocyte mediated cytotoxicity +relationship: negatively_regulates GO:0001909 ! leukocyte mediated cytotoxicity + +[Term] +id: GO:0001912 +name: positive regulation of leukocyte mediated cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity." [GOC:add, ISBN:0781735149, PMID:11911826] +synonym: "activation of leukocyte mediated cytotoxicity" NARROW [] +synonym: "positive regulation of immune cell mediated cytotoxicity" EXACT [] +synonym: "positive regulation of leucocyte mediated cytotoxicity" EXACT [] +synonym: "stimulation of leukocyte mediated cytotoxicity" NARROW [] +synonym: "up regulation of leukocyte mediated cytotoxicity" EXACT [] +synonym: "up-regulation of leukocyte mediated cytotoxicity" EXACT [] +synonym: "upregulation of leukocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity +is_a: GO:0031343 ! positive regulation of cell killing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001909 ! leukocyte mediated cytotoxicity +relationship: positively_regulates GO:0001909 ! leukocyte mediated cytotoxicity + +[Term] +id: GO:0001913 +name: T cell mediated cytotoxicity +namespace: biological_process +def: "The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, GOC:pr, ISBN:0781735149, PMID:11911826] +comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not. +synonym: "T cell mediated apoptosis" EXACT [] +synonym: "T cell mediated cell death" EXACT [] +synonym: "T cell mediated cell killing" EXACT [] +synonym: "T cell mediated cytolysis" RELATED [] +synonym: "T lymphocyte mediated cytotoxicity" EXACT [] +synonym: "T-cell mediated apoptosis" EXACT [] +synonym: "T-cell mediated cell death" EXACT [] +synonym: "T-cell mediated cell killing" EXACT [] +synonym: "T-cell mediated cytotoxicity" EXACT [] +synonym: "T-lymphocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001909 ! leukocyte mediated cytotoxicity +is_a: GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0001914 +name: regulation of T cell mediated cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "regulation of T cell mediated apoptosis" EXACT [] +synonym: "regulation of T cell mediated cell death" EXACT [] +synonym: "regulation of T cell mediated cell killing" EXACT [] +synonym: "regulation of T cell mediated cytolysis" RELATED [] +synonym: "regulation of T lymphocyte mediated cytotoxicity" EXACT [] +synonym: "regulation of T-cell mediated apoptosis" EXACT [] +synonym: "regulation of T-cell mediated cell death" EXACT [] +synonym: "regulation of T-cell mediated cell killing" EXACT [] +synonym: "regulation of T-cell mediated cytolysis" RELATED [] +synonym: "regulation of T-cell mediated cytotoxicity" EXACT [] +synonym: "regulation of T-lymphocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002709 ! regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001913 ! T cell mediated cytotoxicity +relationship: regulates GO:0001913 ! T cell mediated cytotoxicity + +[Term] +id: GO:0001915 +name: negative regulation of T cell mediated cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "down regulation of T cell mediated cytotoxicity" EXACT [] +synonym: "down-regulation of T cell mediated cytotoxicity" EXACT [] +synonym: "downregulation of T cell mediated cytotoxicity" EXACT [] +synonym: "inhibition of T cell mediated cytotoxicity" NARROW [] +synonym: "negative regulation of T cell mediated apoptosis" EXACT [] +synonym: "negative regulation of T cell mediated cell death" EXACT [] +synonym: "negative regulation of T cell mediated cell killing" EXACT [] +synonym: "negative regulation of T cell mediated cytolysis" RELATED [] +synonym: "negative regulation of T lymphocyte mediated cytotoxicity" EXACT [] +synonym: "negative regulation of T-cell mediated apoptosis" EXACT [] +synonym: "negative regulation of T-cell mediated cell death" EXACT [] +synonym: "negative regulation of T-cell mediated cell killing" EXACT [] +synonym: "negative regulation of T-cell mediated cytolysis" RELATED [] +synonym: "negative regulation of T-cell mediated cytotoxicity" EXACT [] +synonym: "negative regulation of T-lymphocyte mediated cytotoxicity" EXACT [] +is_a: GO:0001911 ! negative regulation of leukocyte mediated cytotoxicity +is_a: GO:0001914 ! regulation of T cell mediated cytotoxicity +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001913 ! T cell mediated cytotoxicity +relationship: negatively_regulates GO:0001913 ! T cell mediated cytotoxicity + +[Term] +id: GO:0001916 +name: positive regulation of T cell mediated cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "activation of T cell mediated cytotoxicity" NARROW [] +synonym: "positive regulation of T cell mediated apoptosis" EXACT [] +synonym: "positive regulation of T cell mediated cell death" EXACT [] +synonym: "positive regulation of T cell mediated cell killing" EXACT [] +synonym: "positive regulation of T cell mediated cytolysis" RELATED [] +synonym: "positive regulation of T lymphocyte mediated cytotoxicity" EXACT [] +synonym: "positive regulation of T-cell mediated apoptosis" EXACT [] +synonym: "positive regulation of T-cell mediated cell death" EXACT [] +synonym: "positive regulation of T-cell mediated cell killing" EXACT [] +synonym: "positive regulation of T-cell mediated cytolysis" RELATED [] +synonym: "positive regulation of T-cell mediated cytotoxicity" EXACT [] +synonym: "positive regulation of T-lymphocyte mediated cytotoxicity" EXACT [] +synonym: "stimulation of T cell mediated cytotoxicity" NARROW [] +synonym: "up regulation of T cell mediated cytotoxicity" EXACT [] +synonym: "up-regulation of T cell mediated cytotoxicity" EXACT [] +synonym: "upregulation of T cell mediated cytotoxicity" EXACT [] +is_a: GO:0001912 ! positive regulation of leukocyte mediated cytotoxicity +is_a: GO:0001914 ! regulation of T cell mediated cytotoxicity +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001913 ! T cell mediated cytotoxicity +relationship: positively_regulates GO:0001913 ! T cell mediated cytotoxicity + +[Term] +id: GO:0001917 +name: photoreceptor inner segment +namespace: cellular_component +def: "The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs." [GOC:add, PMID:12019563] +subset: goslim_pir +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0001918 +name: farnesylated protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a farnesylated protein." [GOC:add, PMID:14555765] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0001919 +name: regulation of receptor recycling +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of receptor recycling." [GOC:add] +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001881 ! receptor recycling +relationship: regulates GO:0001881 ! receptor recycling + +[Term] +id: GO:0001920 +name: negative regulation of receptor recycling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of receptor recycling." [GOC:add] +synonym: "down regulation of receptor recycling" EXACT [] +synonym: "down-regulation of receptor recycling" EXACT [] +synonym: "downregulation of receptor recycling" EXACT [] +synonym: "inhibition of receptor recycling" NARROW [] +is_a: GO:0001919 ! regulation of receptor recycling +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0031324 ! negative regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001881 ! receptor recycling +relationship: negatively_regulates GO:0001881 ! receptor recycling + +[Term] +id: GO:0001921 +name: positive regulation of receptor recycling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor recycling." [GOC:add] +synonym: "activation of receptor recycling" NARROW [] +synonym: "stimulation of receptor recycling" NARROW [] +synonym: "up regulation of receptor recycling" EXACT [] +synonym: "up-regulation of receptor recycling" EXACT [] +synonym: "upregulation of receptor recycling" EXACT [] +is_a: GO:0001919 ! regulation of receptor recycling +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0031325 ! positive regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001881 ! receptor recycling +relationship: positively_regulates GO:0001881 ! receptor recycling + +[Term] +id: GO:0001922 +name: B-1 B cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity." [GOC:add, ISBN:0781735149] +comment: Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus. +synonym: "B-1 B lymphocyte homeostasis" EXACT [] +synonym: "B-1 B-cell homeostasis" EXACT [] +synonym: "B-1 B-lymphocyte homeostasis" EXACT [] +is_a: GO:0001782 ! B cell homeostasis + +[Term] +id: GO:0001923 +name: B-1 B cell differentiation +namespace: biological_process +def: "The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity." [GOC:add, ISBN:0781735149] +synonym: "B-1 B cell development" RELATED [GOC:add] +synonym: "B-1 B lymphocyte differentiation" EXACT [] +synonym: "B-1 B-cell differentiation" EXACT [] +synonym: "B-1 B-lymphocyte differentiation" EXACT [] +is_a: GO:0002335 ! mature B cell differentiation + +[Term] +id: GO:0001924 +name: regulation of B-1 B cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of B-1 B cell development" RELATED [GOC:add] +synonym: "regulation of B-1 B lymphocyte differentiation" EXACT [] +synonym: "regulation of B-1 B-cell differentiation" EXACT [] +synonym: "regulation of B-1 B-lymphocyte differentiation" EXACT [] +is_a: GO:0045577 ! regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001923 ! B-1 B cell differentiation +relationship: regulates GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0001925 +name: negative regulation of B-1 B cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of B-1 B cell differentiation" EXACT [] +synonym: "down-regulation of B-1 B cell differentiation" EXACT [] +synonym: "downregulation of B-1 B cell differentiation" EXACT [] +synonym: "inhibition of B-1 B cell differentiation" NARROW [] +synonym: "negative regulation of B-1 B cell development" RELATED [GOC:add] +synonym: "negative regulation of B-1 B lymphocyte differentiation" EXACT [] +synonym: "negative regulation of B-1 B-cell differentiation" EXACT [] +synonym: "negative regulation of B-1 B-lymphocyte differentiation" EXACT [] +is_a: GO:0001924 ! regulation of B-1 B cell differentiation +is_a: GO:0045578 ! negative regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001923 ! B-1 B cell differentiation +relationship: negatively_regulates GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0001926 +name: positive regulation of B-1 B cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of B-1 B cell differentiation" NARROW [] +synonym: "positive regulation of B-1 B cell development" RELATED [GOC:add] +synonym: "positive regulation of B-1 B lymphocyte differentiation" EXACT [] +synonym: "positive regulation of B-1 B-cell differentiation" EXACT [] +synonym: "positive regulation of B-1 B-lymphocyte differentiation" EXACT [] +synonym: "stimulation of B-1 B cell differentiation" NARROW [] +synonym: "up regulation of B-1 B cell differentiation" EXACT [] +synonym: "up-regulation of B-1 B cell differentiation" EXACT [] +synonym: "upregulation of B-1 B cell differentiation" EXACT [] +is_a: GO:0001924 ! regulation of B-1 B cell differentiation +is_a: GO:0045579 ! positive regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001923 ! B-1 B cell differentiation +relationship: positively_regulates GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0001927 +name: exocyst assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex." [GOC:hjd, PMID:9700152, Wikipedia:Exocyst] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0006904 ! vesicle docking involved in exocytosis + +[Term] +id: GO:0001928 +name: regulation of exocyst assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exocyst assembly." [GOC:hjd] +comment: Note that the assembly is regulated by several small GTPases of the Rab and Rho families. +is_a: GO:0017157 ! regulation of exocytosis +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0106020 ! regulation of vesicle docking +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001927 ! exocyst assembly +relationship: regulates GO:0001927 ! exocyst assembly + +[Term] +id: GO:0001929 +name: negative regulation of exocyst assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of exocyst assembly." [GOC:hjd] +synonym: "down regulation of exocyst assembly" EXACT [] +synonym: "down-regulation of exocyst assembly" EXACT [] +synonym: "downregulation of exocyst assembly" EXACT [] +synonym: "inhibition of exocyst assembly" NARROW [] +is_a: GO:0001928 ! regulation of exocyst assembly +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0045920 ! negative regulation of exocytosis +is_a: GO:0106021 ! negative regulation of vesicle docking +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001927 ! exocyst assembly +relationship: negatively_regulates GO:0001927 ! exocyst assembly + +[Term] +id: GO:0001930 +name: positive regulation of exocyst assembly +namespace: biological_process +def: "Any process that increases the rate or extent of exocyst assembly." [GOC:hjd] +synonym: "activation of exocyst assembly" NARROW [] +synonym: "stimulation of exocyst assembly" NARROW [] +synonym: "up regulation of exocyst assembly" EXACT [] +synonym: "up-regulation of exocyst assembly" EXACT [] +synonym: "upregulation of exocyst assembly" EXACT [] +is_a: GO:0001928 ! regulation of exocyst assembly +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0045921 ! positive regulation of exocytosis +is_a: GO:0106022 ! positive regulation of vesicle docking +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001927 ! exocyst assembly +relationship: positively_regulates GO:0001927 ! exocyst assembly + +[Term] +id: GO:0001931 +name: uropod +namespace: cellular_component +def: "A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively." [GOC:add, ISBN:0781735149, PMID:12714569, PMID:12787750] +synonym: "distal pole complex" RELATED [] +synonym: "retractile pole" RELATED [] +synonym: "uropodium" EXACT [] +is_a: GO:0120025 ! plasma membrane bounded cell projection +intersection_of: GO:0120025 ! plasma membrane bounded cell projection +intersection_of: part_of GO:0031254 ! cell trailing edge +relationship: part_of GO:0031254 ! cell trailing edge + +[Term] +id: GO:0001932 +name: regulation of protein phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." [GOC:hjd] +synonym: "regulation of protein amino acid phosphorylation" EXACT [GOC:bf] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:0042325 ! regulation of phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006468 ! protein phosphorylation +relationship: regulates GO:0006468 ! protein phosphorylation + +[Term] +id: GO:0001933 +name: negative regulation of protein phosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein." [GOC:hjd] +synonym: "down regulation of protein amino acid phosphorylation" EXACT [] +synonym: "down-regulation of protein amino acid phosphorylation" EXACT [] +synonym: "downregulation of protein amino acid phosphorylation" EXACT [] +synonym: "inhibition of protein amino acid phosphorylation" NARROW [] +synonym: "negative regulation of protein amino acid phosphorylation" EXACT [GOC:bf] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0042326 ! negative regulation of phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006468 ! protein phosphorylation +relationship: negatively_regulates GO:0006468 ! protein phosphorylation + +[Term] +id: GO:0001934 +name: positive regulation of protein phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." [GOC:hjd] +synonym: "activation of protein amino acid phosphorylation" NARROW [] +synonym: "positive regulation of protein amino acid phosphorylation" EXACT [GOC:bf] +synonym: "stimulation of protein amino acid phosphorylation" NARROW [] +synonym: "up regulation of protein amino acid phosphorylation" EXACT [] +synonym: "up-regulation of protein amino acid phosphorylation" EXACT [] +synonym: "upregulation of protein amino acid phosphorylation" EXACT [] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:0042327 ! positive regulation of phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006468 ! protein phosphorylation +relationship: positively_regulates GO:0006468 ! protein phosphorylation + +[Term] +id: GO:0001935 +name: endothelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149] +is_a: GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0001936 +name: regulation of endothelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001935 ! endothelial cell proliferation +relationship: regulates GO:0001935 ! endothelial cell proliferation + +[Term] +id: GO:0001937 +name: negative regulation of endothelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] +synonym: "down regulation of endothelial cell proliferation" EXACT [] +synonym: "down-regulation of endothelial cell proliferation" EXACT [] +synonym: "downregulation of endothelial cell proliferation" EXACT [] +synonym: "inhibition of endothelial cell proliferation" NARROW [] +is_a: GO:0001936 ! regulation of endothelial cell proliferation +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001935 ! endothelial cell proliferation +relationship: negatively_regulates GO:0001935 ! endothelial cell proliferation + +[Term] +id: GO:0001938 +name: positive regulation of endothelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] +synonym: "activation of endothelial cell proliferation" NARROW [] +synonym: "stimulation of endothelial cell proliferation" NARROW [] +synonym: "up regulation of endothelial cell proliferation" EXACT [] +synonym: "up-regulation of endothelial cell proliferation" EXACT [] +synonym: "upregulation of endothelial cell proliferation" EXACT [] +is_a: GO:0001936 ! regulation of endothelial cell proliferation +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001935 ! endothelial cell proliferation +relationship: positively_regulates GO:0001935 ! endothelial cell proliferation + +[Term] +id: GO:0001939 +name: female pronucleus +namespace: cellular_component +def: "The pronucleus originating from the ovum that is being fertilized." [GOC:hjd, ISBN:0198506732] +is_a: GO:0045120 ! pronucleus + +[Term] +id: GO:0001940 +name: male pronucleus +namespace: cellular_component +def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732] +is_a: GO:0045120 ! pronucleus + +[Term] +id: GO:0001941 +name: postsynaptic membrane organization +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)." [GOC:dph, GOC:pr] +synonym: "post-synaptic membrane organization" EXACT [] +synonym: "postsynaptic membrane organisation" EXACT [] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0099173 ! postsynapse organization + +[Term] +id: GO:0001942 +name: hair follicle development +namespace: biological_process +alt_id: GO:0001943 +def: "The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open." [GOC:dph, UBERON:0002073] +is_a: GO:0022405 ! hair cycle process +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0098773 ! skin epidermis development + +[Term] +id: GO:0001944 +name: vasculature development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409] +synonym: "vascular system development" RELATED [] +is_a: GO:0048731 ! system development +relationship: part_of GO:0072358 ! cardiovascular system development + +[Term] +id: GO:0001945 +name: lymph vessel development +namespace: biological_process +def: "The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure." [GOC:dph, UBERON:0001473] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001944 ! vasculature development + +[Term] +id: GO:0001946 +name: lymphangiogenesis +namespace: biological_process +def: "Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels." [GOC:dph, PMID:11596157] +synonym: "lymph vessel formation" EXACT systematic_synonym [] +xref: Wikipedia:Lymphangiogenesis +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0036303 ! lymph vessel morphogenesis + +[Term] +id: GO:0001947 +name: heart looping +namespace: biological_process +def: "The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation." [GOC:dph, PMID:12094232] +synonym: "cardiac looping" EXACT [] +is_a: GO:0003143 ! embryonic heart tube morphogenesis +relationship: part_of GO:0061371 ! determination of heart left/right asymmetry + +[Term] +id: GO:0001949 +name: sebaceous gland cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell." [GOC:mgi_curators, PMID:15737203] +synonym: "sebocytes differentiation" NARROW [GOC:mgi_curators] +is_a: GO:0009913 ! epidermal cell differentiation +relationship: part_of GO:0048733 ! sebaceous gland development + +[Term] +id: GO:0001950 +name: obsolete plasma membrane enriched fraction +namespace: cellular_component +def: "OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes." [GOC:mgi_curators, PMID:11562363, PMID:15601832] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "plasma membrane enriched fraction" EXACT [] +synonym: "PME fraction" RELATED [GOC:mah] +is_obsolete: true +consider: GO:0005886 + +[Term] +id: GO:0001951 +name: intestinal D-glucose absorption +namespace: biological_process +def: "Uptake of D-glucose into the blood by absorption from the small intestine." [GOC:mgi_curators, PMID:5601832] +is_a: GO:0106001 ! intestinal hexose absorption + +[Term] +id: GO:0001952 +name: regulation of cell-matrix adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix." [GOC:hjd] +is_a: GO:0010810 ! regulation of cell-substrate adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0007160 ! cell-matrix adhesion +relationship: regulates GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0001953 +name: negative regulation of cell-matrix adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix." [GOC:hjd] +synonym: "down regulation of cell-matrix adhesion" EXACT [] +synonym: "down-regulation of cell-matrix adhesion" EXACT [] +synonym: "downregulation of cell-matrix adhesion" EXACT [] +synonym: "inhibition of cell-matrix adhesion" NARROW [] +is_a: GO:0001952 ! regulation of cell-matrix adhesion +is_a: GO:0010812 ! negative regulation of cell-substrate adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0007160 ! cell-matrix adhesion +relationship: negatively_regulates GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0001954 +name: positive regulation of cell-matrix adhesion +namespace: biological_process +def: "Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix." [GOC:hjd] +synonym: "activation of cell-matrix adhesion" NARROW [] +synonym: "stimulation of cell-matrix adhesion" NARROW [] +synonym: "up regulation of cell-matrix adhesion" EXACT [] +synonym: "up-regulation of cell-matrix adhesion" EXACT [] +synonym: "upregulation of cell-matrix adhesion" EXACT [] +is_a: GO:0001952 ! regulation of cell-matrix adhesion +is_a: GO:0010811 ! positive regulation of cell-substrate adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0007160 ! cell-matrix adhesion +relationship: positively_regulates GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0001955 +name: blood vessel maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0001568 ! blood vessel development + +[Term] +id: GO:0001956 +name: positive regulation of neurotransmitter secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] +synonym: "activation of neurotransmitter secretion" NARROW [] +synonym: "stimulation of neurotransmitter secretion" NARROW [] +synonym: "up regulation of neurotransmitter secretion" EXACT [] +synonym: "up-regulation of neurotransmitter secretion" EXACT [] +synonym: "upregulation of neurotransmitter secretion" EXACT [] +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007269 ! neurotransmitter secretion +relationship: positively_regulates GO:0007269 ! neurotransmitter secretion + +[Term] +id: GO:0001957 +name: intramembranous ossification +namespace: biological_process +def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437] +comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. +synonym: "dermal ossification" NARROW [GO_REF:0000034] +synonym: "intramembranous bone ossification" RELATED [GOC:cjm] +xref: Wikipedia:Intramembranous_ossification +is_a: GO:0036072 ! direct ossification + +[Term] +id: GO:0001958 +name: endochondral ossification +namespace: biological_process +def: "Replacement ossification wherein bone tissue replaces cartilage." [GO_REF:0000034, ISBN:0878932437] +xref: Wikipedia:Endochondral_ossification +is_a: GO:0036075 ! replacement ossification +relationship: part_of GO:0060350 ! endochondral bone morphogenesis + +[Term] +id: GO:0001959 +name: regulation of cytokine-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway." [GOC:hjd] +synonym: "regulation of cytokine and chemokine mediated signaling pathway" EXACT [] +synonym: "regulation of cytokine mediated signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of cytokine mediated signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0060759 ! regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019221 ! cytokine-mediated signaling pathway +relationship: regulates GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0001960 +name: negative regulation of cytokine-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway." [GOC:hjd] +synonym: "down regulation of cytokine mediated signaling pathway" EXACT [] +synonym: "down-regulation of cytokine mediated signaling pathway" EXACT [] +synonym: "downregulation of cytokine mediated signaling pathway" EXACT [] +synonym: "inhibition of cytokine mediated signaling pathway" NARROW [] +synonym: "negative regulation of cytokine and chemokine mediated signaling pathway" EXACT [] +synonym: "negative regulation of cytokine mediated signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of cytokine mediated signalling pathway" EXACT [] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0060761 ! negative regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019221 ! cytokine-mediated signaling pathway +relationship: negatively_regulates GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0001961 +name: positive regulation of cytokine-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway." [GOC:hjd] +synonym: "activation of cytokine mediated signaling pathway" NARROW [] +synonym: "positive regulation of cytokine and chemokine mediated signaling pathway" EXACT [] +synonym: "positive regulation of cytokine mediated signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of cytokine mediated signalling pathway" EXACT [] +synonym: "stimulation of cytokine mediated signaling pathway" NARROW [] +synonym: "up regulation of cytokine mediated signaling pathway" EXACT [] +synonym: "up-regulation of cytokine mediated signaling pathway" EXACT [] +synonym: "upregulation of cytokine mediated signaling pathway" EXACT [] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0060760 ! positive regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019221 ! cytokine-mediated signaling pathway +relationship: positively_regulates GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0001962 +name: alpha-1,3-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage." [GOC:hjd, PMID:10854427] +synonym: "isoglobotriaosylceramide synthase" NARROW [] +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0001963 +name: synaptic transmission, dopaminergic +namespace: biological_process +def: "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, GOC:dph] +synonym: "dopaminergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0001964 +name: startle response +namespace: biological_process +def: "An action or movement due to the application of a sudden unexpected stimulus." [GOC:dph] +xref: Wikipedia:Startle_reaction +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0050905 ! neuromuscular process + +[Term] +id: GO:0001965 +name: G-protein alpha-subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide." [GOC:hjd] +synonym: "G-alpha protein subunit binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0001966 +name: thigmotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to touch." [GOC:dph] +synonym: "stereotaxis" EXACT [] +synonym: "taxis in response to mechanical stimulus" BROAD [] +synonym: "taxis in response to touch stimulus" EXACT [] +is_a: GO:0042330 ! taxis + +[Term] +id: GO:0001967 +name: suckling behavior +namespace: biological_process +def: "Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast." [GOC:dph, GOC:pr] +synonym: "nursing behavior" EXACT [] +is_a: GO:0007631 ! feeding behavior + +[Term] +id: GO:0001968 +name: fibronectin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids." [GOC:hjd] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0001969 +name: regulation of activation of membrane attack complex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] +synonym: "regulation of activation of MAC" EXACT [GOC:mah] +synonym: "regulation of activation of TCC" NARROW [GOC:mah] +synonym: "regulation of activation of terminal complement complex" NARROW [GOC:add] +synonym: "regulation of activation of the terminal complement cascade" NARROW [GOC:mah] +synonym: "regulation of MAC assembly" EXACT [GOC:rl] +synonym: "regulation of MAC formation" EXACT [GOC:rl] +synonym: "regulation of membrane attack complex assembly" EXACT [GOC:rl] +synonym: "regulation of membrane attack complex formation" EXACT [GOC:rl] +is_a: GO:0030449 ! regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001905 ! activation of membrane attack complex +relationship: regulates GO:0001905 ! activation of membrane attack complex + +[Term] +id: GO:0001970 +name: positive regulation of activation of membrane attack complex +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] +synonym: "activation of activation of membrane attack complex" NARROW [] +synonym: "positive regulation of activation of MAC" EXACT [GOC:mah] +synonym: "positive regulation of activation of TCC" NARROW [GOC:mah] +synonym: "positive regulation of activation of terminal complement complex" NARROW [GOC:add] +synonym: "positive regulation of activation of the terminal complement cascade" NARROW [GOC:mah] +synonym: "positive regulation of MAC assembly" EXACT [GOC:rl] +synonym: "positive regulation of MAC formation" EXACT [GOC:rl] +synonym: "positive regulation of membrane attack complex assembly" EXACT [GOC:rl] +synonym: "positive regulation of membrane attack complex formation" EXACT [GOC:rl] +synonym: "stimulation of activation of membrane attack complex" NARROW [] +synonym: "up regulation of activation of membrane attack complex" EXACT [] +synonym: "up-regulation of activation of membrane attack complex" EXACT [] +synonym: "upregulation of activation of membrane attack complex" EXACT [] +is_a: GO:0001969 ! regulation of activation of membrane attack complex +is_a: GO:0045917 ! positive regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001905 ! activation of membrane attack complex +relationship: positively_regulates GO:0001905 ! activation of membrane attack complex + +[Term] +id: GO:0001971 +name: negative regulation of activation of membrane attack complex +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] +synonym: "down regulation of activation of membrane attack complex" EXACT [] +synonym: "down-regulation of activation of membrane attack complex" EXACT [] +synonym: "downregulation of activation of membrane attack complex" EXACT [] +synonym: "inhibition of activation of membrane attack complex" NARROW [] +synonym: "negative regulation of activation of MAC" EXACT [GOC:mah] +synonym: "negative regulation of activation of TCC" NARROW [GOC:mah] +synonym: "negative regulation of activation of terminal complement complex" NARROW [GOC:add] +synonym: "negative regulation of activation of the terminal complement cascade" NARROW [GOC:mah] +synonym: "negative regulation of MAC assembly" EXACT [GOC:rl] +synonym: "negative regulation of MAC formation" EXACT [GOC:rl] +synonym: "negative regulation of membrane attack complex assembly" EXACT [GOC:rl] +synonym: "negative regulation of membrane attack complex formation" EXACT [GOC:rl] +is_a: GO:0001969 ! regulation of activation of membrane attack complex +is_a: GO:0045916 ! negative regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001905 ! activation of membrane attack complex +relationship: negatively_regulates GO:0001905 ! activation of membrane attack complex + +[Term] +id: GO:0001972 +name: retinoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid." [GOC:hjd] +is_a: GO:0005501 ! retinoid binding +is_a: GO:0033293 ! monocarboxylic acid binding + +[Term] +id: GO:0001973 +name: G protein-coupled adenosine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:dph] +synonym: "adenosine receptor signaling pathway" RELATED [] +synonym: "adenosine receptor signaling pathway, G-protein coupled" EXACT [PMID:9755289] +synonym: "adenosine receptor signalling pathway" EXACT [GOC:mah] +synonym: "P1 receptor signaling pathway" EXACT [PMID:9755289] +is_a: GO:0035588 ! G protein-coupled purinergic receptor signaling pathway + +[Term] +id: GO:0001974 +name: blood vessel remodeling +namespace: biological_process +def: "The reorganization or renovation of existing blood vessels." [GOC:hjd] +is_a: GO:0048771 ! tissue remodeling + +[Term] +id: GO:0001975 +name: response to amphetamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine." [GOC:dph, GOC:ef] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0014075 ! response to amine +is_a: GO:0097366 ! response to bronchodilator + +[Term] +id: GO:0001976 +name: nervous system process involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The regulation of blood pressure mediated by detection of stimuli and a neurological response." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure regulation by neurological process" EXACT [] +synonym: "fast control of arterial pressure" RELATED [] +synonym: "neurological process involved in regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +synonym: "neurological system process involved in regulation of systemic arterial blood pressure" EXACT [] +is_a: GO:0050877 ! nervous system process +intersection_of: GO:0050877 ! nervous system process +intersection_of: part_of GO:0003073 ! regulation of systemic arterial blood pressure +relationship: part_of GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0001977 +name: renal system process involved in regulation of blood volume +namespace: biological_process +def: "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system." [GOC:dph, GOC:tb, ISBN:0721643949] +synonym: "renal blood volume control of blood pressure" RELATED [] +synonym: "renal regulation of blood volume" RELATED [GOC:dph, GOC:tb] +is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0050878 ! regulation of body fluid levels + +[Term] +id: GO:0001978 +name: regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback +namespace: biological_process +def: "The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control." [GOC:dph, GOC:tb, ISBN:0721643949] +synonym: "baroreceptor feedback control of blood pressure" RELATED [] +synonym: "baroreceptor pressure buffer system" RELATED [ISBN:068340007X] +synonym: "carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0003025 ! regulation of systemic arterial blood pressure by baroreceptor feedback + +[Term] +id: GO:0001979 +name: regulation of systemic arterial blood pressure by chemoreceptor signaling +namespace: biological_process +def: "The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions." [GOC:dph, GOC:tb, ISBN:0721643949] +synonym: "chemoreceptor control of blood pressure" RELATED [] +synonym: "chemoreceptor regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of systemic arterial blood pressure by chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure + +[Term] +id: GO:0001980 +name: regulation of systemic arterial blood pressure by ischemic conditions +namespace: biological_process +def: "The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system." [GOC:dph, GOC:tb, ISBN:0721643949] +synonym: "CNS ischemic response" RELATED [ISBN:0721643949] +synonym: "ischemic control of blood pressure" RELATED [] +synonym: "ischemic regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure + +[Term] +id: GO:0001981 +name: baroreceptor detection of arterial stretch +namespace: biological_process +def: "The series of events by which the change in diameter of an artery is detected and converted to a molecular signal." [GOC:mtg_cardio, ISBN:0721643949] +is_a: GO:0003018 ! vascular process in circulatory system +is_a: GO:0050982 ! detection of mechanical stimulus +relationship: part_of GO:0001978 ! regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback + +[Term] +id: GO:0001982 +name: baroreceptor response to decreased systemic arterial blood pressure +namespace: biological_process +def: "The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels." [GOC:dph, GOC:mtg_cardio, ISBN:0323031951, ISBN:0721643949] +is_a: GO:0001978 ! regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure + +[Term] +id: GO:0001983 +name: baroreceptor response to increased systemic arterial blood pressure +namespace: biological_process +def: "The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels." [GOC:mtg_cardio, ISBN:0323031951, ISBN:0721643949] +is_a: GO:0001978 ! regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback +is_a: GO:0003085 ! negative regulation of systemic arterial blood pressure + +[Term] +id: GO:0001984 +name: artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure +namespace: biological_process +def: "An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure." [ISBN:0721643949] +synonym: "vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure" EXACT [] +is_a: GO:0042311 ! vasodilation +relationship: part_of GO:0001983 ! baroreceptor response to increased systemic arterial blood pressure + +[Term] +id: GO:0001985 +name: negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure." [ISBN:0721643949] +synonym: "down regulation of heart contraction rate in baroreceptor response to increased blood pressure" EXACT [] +synonym: "down-regulation of heart contraction rate in baroreceptor response to increased blood pressure" EXACT [] +synonym: "downregulation of heart contraction rate in baroreceptor response to increased blood pressure" EXACT [] +synonym: "inhibition of heart contraction rate in baroreceptor response to increased blood pressure" NARROW [] +synonym: "negative control of heart contraction rate in baroreceptor response to increased blood pressure" EXACT [] +synonym: "negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure" RELATED [] +synonym: "negative regulation of heart contraction rate in baroreceptor response to increased blood pressure" EXACT [] +is_a: GO:0010459 ! negative regulation of heart rate +intersection_of: GO:0010459 ! negative regulation of heart rate +intersection_of: part_of GO:0001983 ! baroreceptor response to increased systemic arterial blood pressure +relationship: part_of GO:0001983 ! baroreceptor response to increased systemic arterial blood pressure + +[Term] +id: GO:0001986 +name: negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure +namespace: biological_process +def: "Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure" EXACT [] +synonym: "decreased strength of cardiac contraction during baroreceptor response to increased blood pressure" EXACT [] +is_a: GO:0045822 ! negative regulation of heart contraction +relationship: part_of GO:0001983 ! baroreceptor response to increased systemic arterial blood pressure + +[Term] +id: GO:0001987 +name: vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure +namespace: biological_process +def: "A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure." [ISBN:0721643949] +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure + +[Term] +id: GO:0001988 +name: positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure." [ISBN:0721643949] +synonym: "activation of heart contraction rate in baroreceptor response to decreased blood pressure" NARROW [] +synonym: "positive control of heart contraction rate in baroreceptor response to decreased blood pressure" EXACT [] +synonym: "positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure" EXACT [] +synonym: "positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure" RELATED [] +synonym: "stimulation of heart contraction rate in baroreceptor response to decreased blood pressure" NARROW [] +synonym: "up regulation of heart contraction rate in baroreceptor response to decreased blood pressure" EXACT [] +synonym: "up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure" EXACT [] +synonym: "upregulation of heart contraction rate in baroreceptor response to decreased blood pressure" EXACT [] +is_a: GO:0010460 ! positive regulation of heart rate +intersection_of: GO:0010460 ! positive regulation of heart rate +intersection_of: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure +relationship: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure + +[Term] +id: GO:0001989 +name: positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure +namespace: biological_process +def: "Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure." [ISBN:0721643949] +synonym: "increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure" RELATED [] +synonym: "increased strength of cardiac contraction during baroreceptor response to decreased blood pressure" RELATED [] +synonym: "positive regulation of the force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure" RELATED [GOC:tb] +is_a: GO:0045823 ! positive regulation of heart contraction +relationship: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure + +[Term] +id: GO:0001990 +name: regulation of systemic arterial blood pressure by hormone +namespace: biological_process +def: "The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure regulation by hormone" EXACT [] +synonym: "hormonal control of blood pressure" RELATED [] +synonym: "hormonal regulation of blood pressure" EXACT [] +is_a: GO:0003044 ! regulation of systemic arterial blood pressure mediated by a chemical signal +is_a: GO:0050886 ! endocrine process + +[Term] +id: GO:0001991 +name: regulation of systemic arterial blood pressure by circulatory renin-angiotensin +namespace: biological_process +def: "The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen." [ISBN:0721643949] +synonym: "circulatory renin-angiotensin blood pressure regulation" EXACT [] +synonym: "circulatory renin-angiotensin control of blood pressure" RELATED [] +synonym: "circulatory renin-angiotensin regulation of blood pressure" EXACT [] +synonym: "control of blood pressure by circulatory renin-angiotensin" RELATED [] +synonym: "renin-angiotensin blood pressure control" RELATED [] +is_a: GO:0003081 ! regulation of systemic arterial blood pressure by renin-angiotensin + +[Term] +id: GO:0001992 +name: regulation of systemic arterial blood pressure by vasopressin +namespace: biological_process +def: "The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure regulation by vasopressin" EXACT [] +synonym: "vasopressin control of blood pressure" RELATED [] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone + +[Term] +id: GO:0001993 +name: regulation of systemic arterial blood pressure by norepinephrine-epinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system." [ISBN:0721643949] +synonym: "noradrenaline-adrenaline regulation of blood pressure" RELATED [] +synonym: "norepinephrine-epinephrine blood pressure control" RELATED [] +synonym: "norepinephrine-epinephrine blood pressure regulation" EXACT [] +is_a: GO:0003044 ! regulation of systemic arterial blood pressure mediated by a chemical signal + +[Term] +id: GO:0001994 +name: norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure" EXACT [] +synonym: "norepinephrine-epinephrine vasoconstriction during blood pressure control" RELATED [] +synonym: "norepinephrine-epinephrine vasoconstriction during blood pressure regulation" EXACT [] +synonym: "norepinephrine-epinephrine vasoconstriction during control of blood pressure" RELATED [] +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0003321 ! positive regulation of blood pressure by epinephrine-norepinephrine + +[Term] +id: GO:0001995 +name: norepinephrine-epinephrine catabolic process in blood stream +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream." [GOC:hjd] +synonym: "noradrenaline-adrenalin catabolic process in blood stream" EXACT [] +is_a: GO:0042419 ! epinephrine catabolic process +relationship: part_of GO:0001993 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine + +[Term] +id: GO:0001996 +name: positive regulation of heart rate by epinephrine-norepinephrine +namespace: biological_process +def: "The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction." [GOC:dph] +synonym: "activation of heart contraction rate by epinephrine-norepinephrine" NARROW [] +synonym: "increased chronotropy by epinephrine-norepinephrine" RELATED [] +synonym: "positive control of heart contraction rate by epinephrine-norepinephrine" RELATED [] +synonym: "positive regulation of cardiac contraction rate by epinephrine-norepinephrine" EXACT [] +synonym: "positive regulation of heart contraction rate by adrenaline-noradrenaline" EXACT [] +synonym: "positive regulation of heart contraction rate by epinephrine-norepinephrine" RELATED [] +synonym: "stimulation of heart contraction rate by epinephrine-norepinephrine" NARROW [] +synonym: "up regulation of heart contraction rate by epinephrine-norepinephrine" EXACT [] +synonym: "up-regulation of heart contraction rate by epinephrine-norepinephrine" EXACT [] +synonym: "upregulation of heart contraction rate by epinephrine-norepinephrine" EXACT [] +is_a: GO:0010460 ! positive regulation of heart rate +relationship: part_of GO:0003321 ! positive regulation of blood pressure by epinephrine-norepinephrine + +[Term] +id: GO:0001997 +name: positive regulation of the force of heart contraction by epinephrine-norepinephrine +namespace: biological_process +def: "Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings." [GOC:dph, GOC:mtg_cardio] +synonym: "increased force of heart contraction by adrenaline-noradrenaline" EXACT [] +synonym: "increased force of heart contraction by epinephrine-norepinephrine" EXACT [] +synonym: "increased inotropy by epinephrine-norepinephrine" RELATED [] +synonym: "increased strength of cardiac contraction by epinephrine-norepinephrine" EXACT [] +synonym: "positive regulation of heart contraction by adrenaline-noradrenaline" RELATED [] +synonym: "positive regulation of heart contraction by epinephrine-norepinephrine" RELATED [] +is_a: GO:0003099 ! positive regulation of the force of heart contraction by chemical signal +relationship: part_of GO:0003321 ! positive regulation of blood pressure by epinephrine-norepinephrine + +[Term] +id: GO:0001998 +name: angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream." [GOC:mtg_cardio, GOC:pr, ISBN:0721643949] +synonym: "angiotensin mediated vasoconstriction during blood pressure control" RELATED [] +synonym: "angiotensin mediated vasoconstriction during blood pressure regulation" EXACT [] +synonym: "angiotensin mediated vasoconstriction during control of blood pressure" RELATED [] +synonym: "angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure" EXACT [] +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0002034 ! regulation of blood vessel diameter by renin-angiotensin + +[Term] +id: GO:0001999 +name: renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure +namespace: biological_process +def: "The physiological response of the kidneys to a decrease in blood flow." [GOC:dph] +synonym: "renal response to blood flow during renin-angiotensin control of blood pressure" RELATED [] +is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0001991 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin + +[Term] +id: GO:0002000 +name: detection of renal blood flow +namespace: biological_process +def: "The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal." [ISBN:0721643949] +is_a: GO:0050982 ! detection of mechanical stimulus +relationship: part_of GO:0001999 ! renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure + +[Term] +id: GO:0002001 +name: renin secretion into blood stream +namespace: biological_process +def: "The regulated release of renin into the blood stream by juxtoglomerular cells." [ISBN:0721643949] +synonym: "renin release into blood stream" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0023061 ! signal release +relationship: part_of GO:0001999 ! renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure + +[Term] +id: GO:0002002 +name: regulation of angiotensin levels in blood +namespace: biological_process +def: "The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation." [GOC:rl, PMID:21951628, Wikipedia:Angiotensin] +synonym: "control of angiotensin levels in blood" RELATED [] +synonym: "control of blood angiotensin level" RELATED [] +synonym: "regulation of blood angiotensin level" EXACT [] +is_a: GO:0010817 ! regulation of hormone levels +relationship: part_of GO:0001991 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15424 xsd:anyURI + +[Term] +id: GO:0002003 +name: angiotensin maturation +namespace: biological_process +alt_id: GO:0002005 +def: "The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood." [ISBN:0721643949] +synonym: "angiotensin catabolic process in blood" NARROW [] +is_a: GO:0016486 ! peptide hormone processing +relationship: part_of GO:0002002 ! regulation of angiotensin levels in blood + +[Term] +id: GO:0002004 +name: secretion of vasopressin involved in fast regulation of systemic arterial blood pressure +namespace: biological_process +def: "The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure." [ISBN:0721643949] +synonym: "secretion of vasopressin during fast control of blood pressure" RELATED [] +synonym: "secretion of vasopressin during fast regulation of systemic arterial blood pressure" RELATED [GOC:dph] +is_a: GO:0030103 ! vasopressin secretion +relationship: part_of GO:0001992 ! regulation of systemic arterial blood pressure by vasopressin + +[Term] +id: GO:0002006 +name: vasoconstriction by vasopressin involved in systemic arterial blood pressure control +namespace: biological_process +def: "The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream." [GOC:dph, GOC:mtg_cardio, GOC:tb, ISBN:0721643949] +synonym: "vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0001992 ! regulation of systemic arterial blood pressure by vasopressin + +[Term] +id: GO:0002007 +name: detection of hypoxic conditions in blood by chemoreceptor signaling +namespace: biological_process +def: "The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies." [GOC:dph] +synonym: "detection of hypoxic conditions in blood by chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0009593 ! detection of chemical stimulus +relationship: has_part GO:0003022 ! detection of pH by chemoreceptor signaling +relationship: part_of GO:0001979 ! regulation of systemic arterial blood pressure by chemoreceptor signaling +relationship: part_of GO:0070887 ! cellular response to chemical stimulus + +[Term] +id: GO:0002008 +name: excitation of vasomotor center by chemoreceptor signaling +namespace: biological_process +def: "The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure." [GOC:dph] +synonym: "excitation of vasomotor center by chemoreceptor signalling" EXACT [] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0001979 ! regulation of systemic arterial blood pressure by chemoreceptor signaling +relationship: part_of GO:0003084 ! positive regulation of systemic arterial blood pressure + +[Term] +id: GO:0002009 +name: morphogenesis of an epithelium +namespace: biological_process +def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732] +synonym: "epithelium morphogenesis" EXACT [] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0060429 ! epithelium development + +[Term] +id: GO:0002010 +name: excitation of vasomotor center by baroreceptor signaling +namespace: biological_process +def: "The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure." [GOC:dph] +synonym: "excitation of vasomotor center by baroreceptor signalling" EXACT [] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure + +[Term] +id: GO:0002011 +name: morphogenesis of an epithelial sheet +namespace: biological_process +def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl] +is_a: GO:0002009 ! morphogenesis of an epithelium + +[Term] +id: GO:0002012 +name: vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure +namespace: biological_process +def: "A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [GOC:dph, GOC:mtg_cardio] +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0001979 ! regulation of systemic arterial blood pressure by chemoreceptor signaling + +[Term] +id: GO:0002013 +name: detection of carbon dioxide by vasomotor center +namespace: biological_process +def: "The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system." [ISBN:0721643949] +is_a: GO:0003031 ! detection of carbon dioxide +relationship: part_of GO:0001980 ! regulation of systemic arterial blood pressure by ischemic conditions + +[Term] +id: GO:0002014 +name: vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure +namespace: biological_process +def: "The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system." [GOC:mtg_cardio, ISBN:0721643949] +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure +is_a: GO:0042310 ! vasoconstriction +relationship: part_of GO:0001980 ! regulation of systemic arterial blood pressure by ischemic conditions + +[Term] +id: GO:0002015 +name: regulation of systemic arterial blood pressure by atrial baroreceptor feedback +namespace: biological_process +def: "A process that controls blood pressure by sensing the amount of stretch occurring in the atria." [GOC:dph, GOC:tb] +synonym: "atrial baroreceptor regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +synonym: "atrial control of blood pressure" RELATED [] +synonym: "atrial low pressure baroreceptor regulation of blood pressure" EXACT [GOC:mtg_cardio] +synonym: "atrial reflex" RELATED [GOC:dph] +is_a: GO:0003015 ! heart process +relationship: part_of GO:0003025 ! regulation of systemic arterial blood pressure by baroreceptor feedback + +[Term] +id: GO:0002016 +name: regulation of blood volume by renin-angiotensin +namespace: biological_process +def: "The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood." [GOC:dph, GOC:mtg_cardio, GOC:tb, ISBN:0721643949] +synonym: "renin-angiotensin control of body fluid levels" RELATED [] +synonym: "renin-angiotensin regulation of blood volume" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003081 ! regulation of systemic arterial blood pressure by renin-angiotensin + +[Term] +id: GO:0002017 +name: regulation of blood volume by renal aldosterone +namespace: biological_process +def: "The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume." [GOC:dph, GOC:tb, ISBN:0721643949] +synonym: "aldosterone mediated control of body fluids" RELATED [] +synonym: "aldosterone mediated regulation of blood volume" EXACT [GOC:dph, GOC:tb] +synonym: "renal regulation of blood volume by aldosterone" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001977 ! renal system process involved in regulation of blood volume +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure + +[Term] +id: GO:0002018 +name: renin-angiotensin regulation of aldosterone production +namespace: biological_process +def: "The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone." [ISBN:0721643949] +synonym: "renin-angiotensin control of aldosterone production" RELATED [] +is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure +is_a: GO:2000858 ! regulation of aldosterone secretion +intersection_of: GO:0003014 ! renal system process +intersection_of: part_of GO:0002016 ! regulation of blood volume by renin-angiotensin +intersection_of: regulates GO:0035932 ! aldosterone secretion +relationship: part_of GO:0002016 ! regulation of blood volume by renin-angiotensin + +[Term] +id: GO:0002019 +name: regulation of renal output by angiotensin +namespace: biological_process +def: "The process in which angiotensin directly modulates the rate of urine output by the kidney." [GOC:dph, GOC:mtg_cardio, GOC:tb, ISBN:0721643949] +synonym: "angiotensin mediated control of renal output" RELATED [] +synonym: "angiotensin mediated regulation of renal output" EXACT [GOC:dph, GOC:tb] +synonym: "angiotensin-mediated regulation of renal output" EXACT [GOC:dph, GOC:tb] +is_a: GO:0002016 ! regulation of blood volume by renin-angiotensin + +[Term] +id: GO:0002020 +name: protease binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protease or peptidase." [GOC:hjd] +xref: Reactome:R-HSA-1297354 "Acrosin Cleavage" +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0002021 +name: response to dietary excess +namespace: biological_process +def: "The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure." [GOC:pg, GOC:pr, PMID:12161655] +is_a: GO:0031667 ! response to nutrient levels +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0002022 +name: detection of dietary excess +namespace: biological_process +def: "The neurological process in which the brain senses excessive caloric intake." [PMID:12161655] +is_a: GO:0050877 ! nervous system process +relationship: part_of GO:0002021 ! response to dietary excess + +[Term] +id: GO:0002023 +name: reduction of food intake in response to dietary excess +namespace: biological_process +def: "An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients." [GOC:pg, GOC:pr, PMID:12161655, PMID:12840200] +is_a: GO:0042755 ! eating behavior +relationship: part_of GO:0002021 ! response to dietary excess + +[Term] +id: GO:0002024 +name: diet induced thermogenesis +namespace: biological_process +def: "The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system." [PMID:12161655] +is_a: GO:1990845 ! adaptive thermogenesis +relationship: part_of GO:0002021 ! response to dietary excess + +[Term] +id: GO:0002025 +name: norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change." [GOC:mtg_cardio, PMID:10358008] +synonym: "noradrenaline-adrenaline vasodilation involved in regulation of blood pressure" EXACT [] +synonym: "norepinephrine-epinephrine vasodilation during blood pressure regulation" EXACT [] +synonym: "vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure" EXACT [] +is_a: GO:0003085 ! negative regulation of systemic arterial blood pressure +is_a: GO:0042311 ! vasodilation +relationship: part_of GO:0001993 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine + +[Term] +id: GO:0002026 +name: regulation of the force of heart contraction +namespace: biological_process +def: "Any process that modulates the extent of heart contraction, changing the force with which blood is propelled." [GOC:dph, GOC:tb, PMID:10358008] +synonym: "cardiac inotropy" EXACT [GOC:dph, GOC:tb] +synonym: "heart inotropy" EXACT [] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0002027 +name: regulation of heart rate +namespace: biological_process +def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008] +synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of heart contraction rate" EXACT [] +synonym: "regulation of rate of heart contraction" EXACT [] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0002028 +name: regulation of sodium ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] +synonym: "regulation of Na+ transport" EXACT [] +synonym: "regulation of sodium transport" EXACT [] +is_a: GO:0010959 ! regulation of metal ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006814 ! sodium ion transport +relationship: regulates GO:0006814 ! sodium ion transport + +[Term] +id: GO:0002029 +name: desensitization of G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway." [PMID:8396717] +synonym: "desensitisation of G-protein coupled receptor protein signalling pathway" EXACT [] +synonym: "desensitization of G-protein coupled receptor protein signaling pathway" EXACT [] +is_a: GO:0022401 ! negative adaptation of signaling pathway +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway + +[Term] +id: GO:0002030 +name: inhibitory G protein-coupled receptor phosphorylation +namespace: biological_process +def: "The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site." [PMID:8396717] +synonym: "inhibitory G-protein coupled receptor phosphorylation" EXACT [] +is_a: GO:0006468 ! protein phosphorylation +relationship: part_of GO:0002029 ! desensitization of G protein-coupled receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0002031 +name: G protein-coupled receptor internalization +namespace: biological_process +def: "The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle." [PMID:8396717] +synonym: "G-protein coupled receptor internalization" EXACT [] +is_a: GO:0031623 ! receptor internalization +relationship: part_of GO:0002029 ! desensitization of G protein-coupled receptor signaling pathway + +[Term] +id: GO:0002032 +name: desensitization of G protein-coupled receptor signaling pathway by arrestin +namespace: biological_process +def: "The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins." [GOC:dph, GOC:tb, PMID:8396717] +synonym: "arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway" EXACT [] +synonym: "arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "desensitization of G-protein coupled receptor protein signaling pathway by arrestin" EXACT [] +is_a: GO:0002029 ! desensitization of G protein-coupled receptor signaling pathway +is_a: GO:0032091 ! negative regulation of protein binding + +[Term] +id: GO:0002033 +name: angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The process that increases the diameter of a blood vessel via the renin-angiotensin system." [GOC:pr, ISBN:0323031951, PMID:10425188] +synonym: "vasodilation by angiotensin involved in regulation of systemic arterial blood pressure" EXACT [] +is_a: GO:0003085 ! negative regulation of systemic arterial blood pressure +is_a: GO:0042311 ! vasodilation +relationship: part_of GO:0002034 ! regulation of blood vessel diameter by renin-angiotensin + +[Term] +id: GO:0002034 +name: regulation of blood vessel diameter by renin-angiotensin +namespace: biological_process +def: "The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system." [GOC:dph, GOC:pr, GOC:tb] +synonym: "regulation of blood vessel size by renin-angiotensin" BROAD [] +synonym: "renin-angiotensin regulation of blood vessel size" BROAD [GOC:dph, GOC:tb] +is_a: GO:0003072 ! renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure +is_a: GO:0003081 ! regulation of systemic arterial blood pressure by renin-angiotensin +is_a: GO:0097746 ! regulation of blood vessel diameter + +[Term] +id: GO:0002035 +name: brain renin-angiotensin system +namespace: biological_process +def: "The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system." [PMID:2909574] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +is_a: GO:0002016 ! regulation of blood volume by renin-angiotensin + +[Term] +id: GO:0002036 +name: regulation of L-glutamate import across plasma membrane +namespace: biological_process +alt_id: GO:1900920 +def: "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell." [GOC:TermGenie] +synonym: "regulation of L-glutamate import" BROAD [] +synonym: "regulation of L-glutamate transport" BROAD [] +synonym: "regulation of L-glutamate uptake" EXACT [GOC:TermGenie] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098712 ! L-glutamate import across plasma membrane +relationship: regulates GO:0098712 ! L-glutamate import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:34:08Z + +[Term] +id: GO:0002037 +name: negative regulation of L-glutamate import across plasma membrane +namespace: biological_process +alt_id: GO:1900921 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell." [GOC:TermGenie] +synonym: "down regulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "down regulation of L-glutamate transport" BROAD [] +synonym: "down regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "down-regulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-glutamate transport" BROAD [] +synonym: "down-regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "downregulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "downregulation of L-glutamate transport" BROAD [] +synonym: "downregulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "inhibition of L-glutamate import" NARROW [GOC:TermGenie] +synonym: "inhibition of L-glutamate transport" NARROW [] +synonym: "inhibition of L-glutamate uptake" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-glutamate import" BROAD [] +synonym: "negative regulation of L-glutamate transport" BROAD [] +synonym: "negative regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "regulation of L-glutamate import" BROAD [] +is_a: GO:0002036 ! regulation of L-glutamate import across plasma membrane +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098712 ! L-glutamate import across plasma membrane +relationship: negatively_regulates GO:0098712 ! L-glutamate import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:34:30Z + +[Term] +id: GO:0002038 +name: positive regulation of L-glutamate import across plasma membrane +namespace: biological_process +alt_id: GO:1900922 +def: "Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell." [GOC:TermGenie] +synonym: "activation of L-glutamate import" NARROW [GOC:TermGenie] +synonym: "activation of L-glutamate transport" NARROW [] +synonym: "activation of L-glutamate uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-glutamate import" BROAD [] +synonym: "positive regulation of L-glutamate transport" BROAD [] +synonym: "positive regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "stimulation of L-glutamate transport" NARROW [] +synonym: "up regulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "up regulation of L-glutamate transport" BROAD [] +synonym: "up regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "up-regulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-glutamate transport" EXACT [] +synonym: "up-regulation of L-glutamate uptake" RELATED [GOC:TermGenie] +synonym: "upregulation of L-glutamate import" EXACT [GOC:TermGenie] +synonym: "upregulation of L-glutamate transport" BROAD [] +synonym: "upregulation of L-glutamate uptake" RELATED [GOC:TermGenie] +is_a: GO:0002036 ! regulation of L-glutamate import across plasma membrane +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098712 ! L-glutamate import across plasma membrane +relationship: positively_regulates GO:0098712 ! L-glutamate import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:34:38Z + +[Term] +id: GO:0002039 +name: p53 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one of the p53 family of proteins." [GOC:hjd] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0002040 +name: sprouting angiogenesis +namespace: biological_process +def: "The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation." [PMID:16391003, PMID:23031691] +is_a: GO:0001525 ! angiogenesis + +[Term] +id: GO:0002041 +name: intussusceptive angiogenesis +namespace: biological_process +def: "The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars." [PMID:16391003] +is_a: GO:0001525 ! angiogenesis + +[Term] +id: GO:0002042 +name: cell migration involved in sprouting angiogenesis +namespace: biological_process +def: "The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis." [PMID:16391003] +is_a: GO:0043534 ! blood vessel endothelial cell migration +relationship: part_of GO:0002040 ! sprouting angiogenesis + +[Term] +id: GO:0002043 +name: blood vessel endothelial cell proliferation involved in sprouting angiogenesis +namespace: biological_process +def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis." [GOC:dph, GOC:tb, PMID:16391003] +synonym: "blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001935 ! endothelial cell proliferation +relationship: part_of GO:0002040 ! sprouting angiogenesis + +[Term] +id: GO:0002044 +name: blood vessel endothelial cell migration involved in intussusceptive angiogenesis +namespace: biological_process +def: "The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis." [PMID:16391003] +is_a: GO:0043534 ! blood vessel endothelial cell migration +relationship: part_of GO:0002041 ! intussusceptive angiogenesis + +[Term] +id: GO:0002045 +name: regulation of cell adhesion involved in intussusceptive angiogenesis +namespace: biological_process +def: "The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis." [PMID:16391003] +is_a: GO:0030155 ! regulation of cell adhesion +intersection_of: GO:0030155 ! regulation of cell adhesion +intersection_of: part_of GO:0002041 ! intussusceptive angiogenesis +relationship: part_of GO:0002041 ! intussusceptive angiogenesis + +[Term] +id: GO:0002046 +name: opsin binding +namespace: molecular_function +alt_id: GO:0016030 +def: "Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception." [GOC:hjd] +synonym: "metarhodopsin binding" NARROW [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0002047 +name: phenazine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring." [GOC:dph] +synonym: "acridizine biosynthesis" RELATED [] +synonym: "acridizine biosynthetic process" RELATED [] +synonym: "azophenylene biosynthesis" RELATED [] +synonym: "azophenylene biosynthetic process" RELATED [] +synonym: "dibenzo-p-diazine biosynthesis" RELATED [] +synonym: "dibenzo-p-diazine biosynthetic process" RELATED [] +synonym: "dibenzopyrazine biosynthesis" RELATED [] +synonym: "dibenzopyrazine biosynthetic process" RELATED [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0002048 +name: pyoverdine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the siderochrome pyoverdine." [PMID:15317763] +synonym: "pyoverdine metabolism" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process + +[Term] +id: GO:0002049 +name: pyoverdine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine." [PMID:15317763] +is_a: GO:0002048 ! pyoverdine metabolic process +is_a: GO:0019290 ! siderophore biosynthetic process + +[Term] +id: GO:0002050 +name: pyoverdine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine." [PMID:15317763] +is_a: GO:0002048 ! pyoverdine metabolic process +is_a: GO:0046215 ! siderophore catabolic process + +[Term] +id: GO:0002051 +name: osteoblast fate commitment +namespace: biological_process +def: "The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone." [GOC:dph] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0001649 ! osteoblast differentiation + +[Term] +id: GO:0002052 +name: positive regulation of neuroblast proliferation +namespace: biological_process +def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] +synonym: "activation of neuroblast proliferation" NARROW [] +synonym: "stimulation of neuroblast proliferation" NARROW [] +synonym: "up regulation of neuroblast proliferation" EXACT [] +synonym: "up-regulation of neuroblast proliferation" EXACT [] +synonym: "upregulation of neuroblast proliferation" EXACT [] +is_a: GO:0050769 ! positive regulation of neurogenesis +is_a: GO:1902692 ! regulation of neuroblast proliferation +is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation +is_a: GO:2000648 ! positive regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007405 ! neuroblast proliferation +relationship: positively_regulates GO:0007405 ! neuroblast proliferation + +[Term] +id: GO:0002053 +name: positive regulation of mesenchymal cell proliferation +namespace: biological_process +def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] +synonym: "activation of mesenchymal cell proliferation" NARROW [] +synonym: "stimulation of mesenchymal cell proliferation" NARROW [] +synonym: "up regulation of mesenchymal cell proliferation" EXACT [] +synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] +synonym: "upregulation of mesenchymal cell proliferation" EXACT [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010463 ! mesenchymal cell proliferation +relationship: positively_regulates GO:0010463 ! mesenchymal cell proliferation + +[Term] +id: GO:0002054 +name: nucleobase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases." [GOC:hjd] +subset: goslim_pir +is_a: GO:0036094 ! small molecule binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0002055 +name: adenine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with adenine, a purine base." [GOC:hjd] +synonym: "6-aminopurine binding" EXACT [] +is_a: GO:0002060 ! purine nucleobase binding + +[Term] +id: GO:0002056 +name: cytosine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cytosine." [GOC:hjd, GOC:vw] +is_a: GO:0002061 ! pyrimidine nucleobase binding + +[Term] +id: GO:0002057 +name: guanine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with guanine." [GOC:hjd] +is_a: GO:0002060 ! purine nucleobase binding + +[Term] +id: GO:0002058 +name: uracil binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with uracil." [GOC:hjd] +is_a: GO:0002061 ! pyrimidine nucleobase binding +is_a: GO:0008144 ! drug binding + +[Term] +id: GO:0002059 +name: thymine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thymine." [GOC:hjd] +is_a: GO:0002061 ! pyrimidine nucleobase binding + +[Term] +id: GO:0002060 +name: purine nucleobase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton." [GOC:hjd] +synonym: "purine base binding" EXACT [GOC:go_curators] +synonym: "purine binding" RELATED [] +is_a: GO:0002054 ! nucleobase binding + +[Term] +id: GO:0002061 +name: pyrimidine nucleobase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton." [GOC:hjd] +synonym: "1,3-diazine binding" NARROW [] +synonym: "pyrimidine base binding" EXACT [GOC:go_curators] +synonym: "pyrimidine binding" RELATED [] +is_a: GO:0002054 ! nucleobase binding + +[Term] +id: GO:0002062 +name: chondrocyte differentiation +namespace: biological_process +def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0051216 ! cartilage development + +[Term] +id: GO:0002063 +name: chondrocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0002062 ! chondrocyte differentiation + +[Term] +id: GO:0002064 +name: epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0002065 +name: columnar/cuboidal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0002066 +name: columnar/cuboidal epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0002065 ! columnar/cuboidal epithelial cell differentiation + +[Term] +id: GO:0002067 +name: glandular epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] +is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation + +[Term] +id: GO:0002068 +name: glandular epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] +is_a: GO:0002066 ! columnar/cuboidal epithelial cell development +relationship: part_of GO:0002067 ! glandular epithelial cell differentiation + +[Term] +id: GO:0002069 +name: columnar/cuboidal epithelial cell maturation +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] +is_a: GO:0002070 ! epithelial cell maturation +relationship: part_of GO:0002066 ! columnar/cuboidal epithelial cell development + +[Term] +id: GO:0002070 +name: epithelial cell maturation +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0002064 ! epithelial cell development + +[Term] +id: GO:0002071 +name: glandular epithelial cell maturation +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] +is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation +relationship: part_of GO:0002068 ! glandular epithelial cell development + +[Term] +id: GO:0002072 +name: optic cup morphogenesis involved in camera-type eye development +namespace: biological_process +def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437] +synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT [] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0060900 ! embryonic camera-type eye formation + +[Term] +id: GO:0002074 +name: extraocular skeletal muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_muscle, GOC:mtg_sensu, MA:0001271, PMID:16638982] +is_a: GO:0007519 ! skeletal muscle tissue development +is_a: GO:0060538 ! skeletal muscle organ development +relationship: part_of GO:0043010 ! camera-type eye development + +[Term] +id: GO:0002075 +name: somitomeric trunk muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus." [GOC:dph, PMID:16638982] +is_a: GO:0060538 ! skeletal muscle organ development + +[Term] +id: GO:0002076 +name: osteoblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0001649 ! osteoblast differentiation + +[Term] +id: GO:0002077 +name: acrosome matrix dispersal +namespace: biological_process +def: "The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane." [GOC:dph, PMID:3886029] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process +relationship: part_of GO:0007340 ! acrosome reaction + +[Term] +id: GO:0002078 +name: membrane fusion involved in acrosome reaction +namespace: biological_process +def: "The fusion of the plasma membrane of the sperm with the outer acrosomal membrane." [GOC:dph, PMID:3886029] +synonym: "membrane fusion involved in the acrosomal reaction" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0061025 ! membrane fusion +intersection_of: GO:0061025 ! membrane fusion +intersection_of: part_of GO:0007340 ! acrosome reaction +relationship: part_of GO:0007340 ! acrosome reaction + +[Term] +id: GO:0002079 +name: inner acrosomal membrane +namespace: cellular_component +def: "The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane." [GOC:dph, PMID:3899643, PMID:8936405] +comment: Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer. +is_a: GO:0098589 ! membrane region +relationship: part_of GO:0002080 ! acrosomal membrane + +[Term] +id: GO:0002080 +name: acrosomal membrane +namespace: cellular_component +def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0001669 ! acrosomal vesicle + +[Term] +id: GO:0002081 +name: outer acrosomal membrane +namespace: cellular_component +def: "The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction." [GOC:dph, PMID:8936405] +comment: Note that this term is not a descendant of 'organelle outer membrane ; GO:0031968' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer. +is_a: GO:0098589 ! membrane region +relationship: part_of GO:0002080 ! acrosomal membrane + +[Term] +id: GO:0002082 +name: regulation of oxidative phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis." [GOC:dph] +synonym: "OXPHOS" EXACT [] +is_a: GO:0042325 ! regulation of phosphorylation +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006119 ! oxidative phosphorylation +relationship: regulates GO:0006119 ! oxidative phosphorylation + +[Term] +id: GO:0002083 +name: 4-hydroxybenzoate decaprenyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate." [MetaCyc:RXN-9230] +xref: EC:2.5.1.39 +xref: MetaCyc:RXN-9230 +xref: Reactome:R-HSA-2162192 "PHB and all-E-10PrP2 are combined into DHB by COQ2" +is_a: GO:0002094 ! polyprenyltransferase activity + +[Term] +id: GO:0002084 +name: protein depalmitoylation +namespace: biological_process +def: "The removal of palymitoyl groups from a lipoprotein." [GOC:hjd] +is_a: GO:0035601 ! protein deacylation +is_a: GO:0042159 ! lipoprotein catabolic process +is_a: GO:0098734 ! macromolecule depalmitoylation + +[Term] +id: GO:0002085 +name: inhibition of neuroepithelial cell differentiation +namespace: biological_process +def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814] +synonym: "negative regulation of neural plate formation" NARROW [GOC:dph, GOC:tb] +synonym: "repression of premature neural plate formation" NARROW [GOC:dph, GOC:tb] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0048505 ! regulation of timing of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation +relationship: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation + +[Term] +id: GO:0002086 +name: diaphragm contraction +namespace: biological_process +def: "A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange." [GOC:dph, GOC:mtg_muscle, PMID:12458206] +is_a: GO:0003011 ! involuntary skeletal muscle contraction +is_a: GO:0003016 ! respiratory system process +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0002087 +name: regulation of respiratory gaseous exchange by nervous system process +namespace: biological_process +def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206] +synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT [] +is_a: GO:0044065 ! regulation of respiratory system process +is_a: GO:0050877 ! nervous system process +intersection_of: GO:0050877 ! nervous system process +intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system + +[Term] +id: GO:0002088 +name: lens development in camera-type eye +namespace: biological_process +def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333] +synonym: "lens development" EXACT [] +synonym: "lens development in camera-style eye" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043010 ! camera-type eye development + +[Term] +id: GO:0002089 +name: lens morphogenesis in camera-type eye +namespace: biological_process +def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu] +synonym: "lens morphogenesis" EXACT [] +synonym: "lens morphogenesis in camera-style eye" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0002088 ! lens development in camera-type eye +relationship: part_of GO:0048593 ! camera-type eye morphogenesis + +[Term] +id: GO:0002090 +name: regulation of receptor internalization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor internalization." [GOC:hjd] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031623 ! receptor internalization +relationship: regulates GO:0031623 ! receptor internalization + +[Term] +id: GO:0002091 +name: negative regulation of receptor internalization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization." [GOC:hjd] +synonym: "down regulation of receptor internalization" EXACT [] +synonym: "down-regulation of receptor internalization" EXACT [] +synonym: "downregulation of receptor internalization" EXACT [] +synonym: "inhibition of receptor internalization" NARROW [] +is_a: GO:0002090 ! regulation of receptor internalization +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0048261 ! negative regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031623 ! receptor internalization +relationship: negatively_regulates GO:0031623 ! receptor internalization + +[Term] +id: GO:0002092 +name: positive regulation of receptor internalization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor internalization." [GOC:hjd] +synonym: "activation of receptor internalization" NARROW [] +synonym: "stimulation of receptor internalization" NARROW [] +synonym: "up regulation of receptor internalization" EXACT [] +synonym: "up-regulation of receptor internalization" EXACT [] +synonym: "upregulation of receptor internalization" EXACT [] +is_a: GO:0002090 ! regulation of receptor internalization +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0048260 ! positive regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031623 ! receptor internalization +relationship: positively_regulates GO:0031623 ! receptor internalization + +[Term] +id: GO:0002093 +name: auditory receptor cell morphogenesis +namespace: biological_process +def: "Any process that alters the size or shape of an auditory receptor cell." [GOC:dph, GOC:tb] +synonym: "hair cell morphogenesis" BROAD [GO:dph] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation +relationship: part_of GO:0042472 ! inner ear morphogenesis +relationship: part_of GO:0060117 ! auditory receptor cell development + +[Term] +id: GO:0002094 +name: polyprenyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor)." [GOC:hjd] +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0002095 +name: caveolar macromolecular signaling complex +namespace: cellular_component +def: "A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3)." [PMID:16648270] +synonym: "caveolar macromolecular signalling complex" EXACT [] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005901 ! caveola + +[Term] +id: GO:0002096 +name: polkadots +namespace: cellular_component +def: "A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals." [PMID:14724296, PMID:16495340] +comment: Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0002097 +name: tRNA wobble base modification +namespace: biological_process +def: "The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified." [GOC:hjd, ISBN:155581073X] +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0002098 +name: tRNA wobble uridine modification +namespace: biological_process +def: "The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002097 ! tRNA wobble base modification + +[Term] +id: GO:0002099 +name: tRNA wobble guanine modification +namespace: biological_process +def: "The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002097 ! tRNA wobble base modification + +[Term] +id: GO:0002100 +name: tRNA wobble adenosine to inosine editing +namespace: biological_process +def: "The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002097 ! tRNA wobble base modification +is_a: GO:0006382 ! adenosine to inosine editing + +[Term] +id: GO:0002101 +name: tRNA wobble cytosine modification +namespace: biological_process +def: "The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002097 ! tRNA wobble base modification + +[Term] +id: GO:0002102 +name: podosome +namespace: cellular_component +def: "An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm." [PMID:12837608, PMID:15890982] +comment: Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation. +xref: Wikipedia:Podosome +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0015629 ! actin cytoskeleton +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0002103 +name: endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0000478 ! endonucleolytic cleavage involved in rRNA processing + +[Term] +id: GO:0002104 +name: endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0002103 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) + +[Term] +id: GO:0002105 +name: endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0002103 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) + +[Term] +id: GO:0002106 +name: endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) +namespace: biological_process +def: "Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators] +is_a: GO:0002103 ! endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) + +[Term] +id: GO:0002107 +name: generation of mature 3'-end of 5S rRNA generated by RNA polymerase III +namespace: biological_process +def: "The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end." [GOC:hjd, PMID:16387655, PMID:1748637, PMID:1902221, PMID:8389357] +is_a: GO:0000481 ! maturation of 5S rRNA +is_a: GO:0031125 ! rRNA 3'-end processing + +[Term] +id: GO:0002108 +name: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0000470 ! maturation of LSU-rRNA + +[Term] +id: GO:0002109 +name: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) +namespace: biological_process +def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators] +is_a: GO:0030490 ! maturation of SSU-rRNA + +[Term] +id: GO:0002110 +name: cotranscriptional mitochondrial rRNA nucleotide insertion +namespace: biological_process +def: "The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis." [GOC:curators, ISBN:1555811337, PMID:8306965] +is_a: GO:0000154 ! rRNA modification +is_a: GO:0070705 ! RNA nucleotide insertion + +[Term] +id: GO:0002111 +name: BRCA2-BRAF35 complex +namespace: cellular_component +def: "A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis." [GOC:hjd, PMID:11207365] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0002112 +name: interleukin-33 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-33 receptor." [GOC:hjd] +synonym: "IL-33" NARROW [GOC:mah] +synonym: "interleukin-33 receptor ligand" NARROW [GOC:mah] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0002113 +name: interleukin-33 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-33." [GOC:hjd] +synonym: "IL-33 binding" EXACT [GOC:mah] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0002114 +name: interleukin-33 receptor activity +namespace: molecular_function +def: "Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, GOC:signaling] +synonym: "IL-33 receptor activity" EXACT [GOC:mah] +synonym: "IL-33R" EXACT [GOC:mah] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0002113 ! interleukin-33 binding +relationship: part_of GO:0038172 ! interleukin-33-mediated signaling pathway + +[Term] +id: GO:0002115 +name: store-operated calcium entry +namespace: biological_process +def: "A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum." [GOC:hjd, PMID:11120592, PMID:17956991] +comment: SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum. +synonym: "calcium ion import" BROAD [] +synonym: "capacitative calcium entry" EXACT [] +synonym: "SOCE" EXACT [] +synonym: "store-operated calcium import" EXACT [] +is_a: GO:0006816 ! calcium ion transport + +[Term] +id: GO:0002116 +name: semaphorin receptor complex +namespace: cellular_component +def: "A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor." [GOC:hjd, PMID:10934324, PMID:12367632, PMID:12613544] +synonym: "plexin-neurophilin complex" EXACT [] +is_a: GO:0043235 ! receptor complex + +[Term] +id: GO:0002117 +name: amphibian larval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form." [GOC:bf, GOC:go_curators, http://www.livingunderworld.org/biology/] +is_a: GO:0002164 ! larval development + +[Term] +id: GO:0002118 +name: aggressive behavior +namespace: biological_process +def: "A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual." [GOC:hjd] +synonym: "aggression" EXACT [] +xref: Wikipedia:Aggression +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0002119 +name: nematode larval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv] +is_a: GO:0002164 ! larval development + +[Term] +id: GO:0002120 +name: obsolete predatory behavior +namespace: biological_process +def: "OBSOLETE. Aggressive behavior involving attack on prey by a predator." [GOC:hjd] +comment: This term was obsoleted because it is outside the scope of GO. +synonym: "predatory aggression" EXACT [] +synonym: "predatory aggressive behavior" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18568 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0002121 +name: inter-male aggressive behavior +namespace: biological_process +def: "Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious." [GOC:hjd] +synonym: "inter-male aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002122 +name: fear-induced aggressive behavior +namespace: biological_process +def: "Aggressive behavior associated with attempts to flee from a threat." [GOC:hjd] +synonym: "fear-induced aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002123 +name: irritable aggressive behavior +namespace: biological_process +def: "Aggressive behavior induced by frustration and directed against an available target." [GOC:hjd] +synonym: "irritable aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002124 +name: territorial aggressive behavior +namespace: biological_process +def: "Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics." [GOC:hjd] +synonym: "territorial aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002125 +name: maternal aggressive behavior +namespace: biological_process +def: "Aggressive behavior of a female to protect her offspring from a threat." [GOC:hjd] +comment: Paternal aggression also exists. Serves to protect the offspring from intruders. +synonym: "maternal aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002126 +name: instrumental aggressive behavior +namespace: biological_process +def: "Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation." [GOC:hjd] +synonym: "instrumental aggression" EXACT [] +is_a: GO:0002118 ! aggressive behavior + +[Term] +id: GO:0002127 +name: tRNA wobble base cytosine methylation +namespace: biological_process +def: "The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position." [GOC:hjd, ISBN:155581073X] +synonym: "wobble position m5C biosynthesis" EXACT [] +is_a: GO:0002101 ! tRNA wobble cytosine modification +is_a: GO:0002946 ! tRNA C5-cytosine methylation + +[Term] +id: GO:0002128 +name: tRNA nucleoside ribose methylation +namespace: biological_process +def: "The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0030488 ! tRNA methylation + +[Term] +id: GO:0002129 +name: wobble position guanine ribose methylation +namespace: biological_process +def: "The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002130 ! wobble position ribose methylation +is_a: GO:0002938 ! tRNA guanine ribose methylation + +[Term] +id: GO:0002130 +name: wobble position ribose methylation +namespace: biological_process +def: "The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002128 ! tRNA nucleoside ribose methylation + +[Term] +id: GO:0002131 +name: wobble position cytosine ribose methylation +namespace: biological_process +def: "The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002130 ! wobble position ribose methylation + +[Term] +id: GO:0002132 +name: wobble position uridine ribose methylation +namespace: biological_process +def: "The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0002130 ! wobble position ribose methylation + +[Term] +id: GO:0002133 +name: polycystin complex +namespace: cellular_component +def: "A stable heterodimeric complex composed of polycystin-1 and polycystin-2." [GOC:hjd, PMID:11901144] +comment: Different forms of the complex differing in type of N-glycosylation of polycystin-1 can exist (endoglycosidase sensitive and endoglycosidase resistant). +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0002134 +name: UTP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with UTP, uridine 5'-triphosphate." [GOC:hjd, ISBN:0198506732] +is_a: GO:0032557 ! pyrimidine ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0002135 +name: CTP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with CTP, cytidine 5'-triphosphate." [GOC:hjd, ISBN:0124020607] +is_a: GO:0032557 ! pyrimidine ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0002136 +name: tRNA wobble base lysidine biosynthesis +namespace: biological_process +def: "The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine." [PMID:15894617] +comment: Exclusively located at the anticodon wobble position (i.e., position 34) of eubacterial and some organellar tRNAIle2. This modification converts the codon specificity from AUG to AUA, and it also converts the aminoacylation specificity of the tRNA from methionine to isoleucine. Requires ATP. +is_a: GO:0002101 ! tRNA wobble cytosine modification + +[Term] +id: GO:0002138 +name: retinoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A." [GOC:hjd] +synonym: "retinoic acid anabolic process" EXACT [] +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0042573 ! retinoic acid metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +created_by: hjd +creation_date: 2009-05-01T10:53:24Z + +[Term] +id: GO:0002139 +name: stereocilia coupling link +namespace: cellular_component +def: "A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle." [PMID:16775142] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032421 ! stereocilium bundle +created_by: hjd +creation_date: 2009-05-06T10:25:38Z + +[Term] +id: GO:0002140 +name: stereocilia tip link +namespace: cellular_component +def: "A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia." [PMID:1108787] +is_a: GO:0002139 ! stereocilia coupling link +created_by: hjd +creation_date: 2009-05-06T10:28:10Z + +[Term] +id: GO:0002141 +name: stereocilia ankle link +namespace: cellular_component +def: "A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia." [PMID:17567809] +is_a: GO:0002139 ! stereocilia coupling link +created_by: hjd +creation_date: 2009-05-06T10:31:56Z + +[Term] +id: GO:0002142 +name: stereocilia ankle link complex +namespace: cellular_component +def: "A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin." [PMID:16775142] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0002141 ! stereocilia ankle link +created_by: hjd +creation_date: 2009-05-06T10:33:57Z + +[Term] +id: GO:0002143 +name: tRNA wobble position uridine thiolation +namespace: biological_process +def: "The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps." [PMID:16871210] +comment: In E. coli, the first step of the reaction is reductive elimination of sulfur from L-cysteine by IscS cysteine desulfurase to form an enzyme-bound cysteine-persulfide intermediate. Then, five essential gene products, TusA, TusB, TusC, TusD and TusE, mediate a sulfur relay that delivers the terminal sulfur of persulfide from IscS to MnmA12. The last protein, MnmA catalyzes the transfer of the sulfur from IscS to an ATP activated U34 of the tRNA. +synonym: "tRNA wobble uridine thiolation" EXACT [GOC:mah] +synonym: "wobble position s2U biosynthesis" EXACT [] +is_a: GO:0002098 ! tRNA wobble uridine modification +is_a: GO:0034227 ! tRNA thio-modification +created_by: hjd +creation_date: 2009-05-06T05:05:40Z + +[Term] +id: GO:0002144 +name: cytosolic tRNA wobble base thiouridylase complex +namespace: cellular_component +def: "A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets." [PMID:17062623, PMID:18391219] +synonym: "Cut1-Cut2 complex" NARROW [] +synonym: "tRNA thiouridylase" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: hjd +creation_date: 2009-05-08T02:32:55Z + +[Term] +id: GO:0002145 +name: 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+)." [MetaCyc:RXN0-3543] +synonym: "HMP-PP diphosphatase" EXACT [] +synonym: "HMP-PP pyrophosphatase" EXACT [] +xref: MetaCyc:RXN0-3543 +is_a: GO:0016462 ! pyrophosphatase activity +created_by: hjd +creation_date: 2009-06-10T11:21:35Z + +[Term] +id: GO:0002146 +name: obsolete steroid hormone receptor import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus." [GOC:hjd] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "steroid hormone receptor nuclear translocation" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0006606 +consider: GO:0042306 +created_by: hjd +creation_date: 2009-07-09T02:34:42Z + +[Term] +id: GO:0002147 +name: obsolete glucocorticoid receptor import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus." [GOC:hjd] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "glucocorticoid receptor nuclear translocation" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0042306 +created_by: hjd +creation_date: 2009-07-09T02:36:09Z + +[Term] +id: GO:0002148 +name: hypochlorous acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hypochlorous acid." [GOC:add, PMID:10085024, PMID:176150] +synonym: "HClO metabolic process" EXACT [] +synonym: "HOCl metabolic process" EXACT [] +synonym: "hypochlorite metabolic process" RELATED [] +synonym: "hypochlorous acid metabolism" EXACT [] +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:0072593 ! reactive oxygen species metabolic process +created_by: hjd +creation_date: 2009-10-13T10:27:48Z + +[Term] +id: GO:0002149 +name: hypochlorous acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hypochlorous acid." [GOC:add, PMID:10085024, PMID:176150] +comment: Note that this reaction is catalyzed by myeloperoxidase in neutrophils. +synonym: "HClO biosynthetic process" EXACT [] +synonym: "HOCl biosynthetic process" EXACT [] +synonym: "hypochlorite biosynthetic process" RELATED [] +synonym: "hypochlorous acid biosynthesis" EXACT [] +is_a: GO:0002148 ! hypochlorous acid metabolic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:1903409 ! reactive oxygen species biosynthetic process +created_by: hjd +creation_date: 2009-10-13T10:32:35Z + +[Term] +id: GO:0002150 +name: hypochlorous acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hypochlorous acid." [GOC:add] +synonym: "HClO catabolic process" EXACT [] +synonym: "HOCl catabolic process" EXACT [] +synonym: "hypochlorite catabolic process" RELATED [] +synonym: "hypochlorous acid catabolism" EXACT [] +is_a: GO:0002148 ! hypochlorous acid metabolic process +is_a: GO:0044282 ! small molecule catabolic process +created_by: hjd +creation_date: 2009-10-13T10:36:09Z + +[Term] +id: GO:0002151 +name: G-quadruplex RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad." [PMID:18294969, PMID:18568163, PMID:19330720] +comment: The structures of RNA and DNA G quartets differ regarding sugar conformation so that a protein binding to the RNA structure might not bind to the DNA structure. +synonym: "G quadruplex binding" EXACT [GOC:mah] +synonym: "G quartet binding" BROAD [GOC:hjd] +synonym: "G quartet RNA binding" EXACT [GOC:hjd] +synonym: "G-quartet binding" BROAD [GOC:mah] +is_a: GO:0003723 ! RNA binding +created_by: hjd +creation_date: 2009-10-22T01:38:02Z + +[Term] +id: GO:0002152 +name: bile acid conjugation +namespace: biological_process +def: "The process in which bile acids are covalently linked to taurine or glycine." [PMID:1094911, PMID:708413] +comment: The bile acid is first activated using CoA by cholate-CoA ligase activity(GO:0047747), then conjugated to taurine or glycine by glycine N-choloyltransferase activity (GO:0047963; appears to use either glycine or taurine). +is_a: GO:0008206 ! bile acid metabolic process +created_by: hjd +creation_date: 2009-10-29T01:41:51Z + +[Term] +id: GO:0002153 +name: steroid receptor RNA activator RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding." [GOC:vw, PMID:10199399, PMID:15180993] +comment: Note: there is also evidence that the RNA itself may code a protein (solution structure of mouse steroid receptor RNA activator 1 (SRA1) protein submitted to PDB by Riken). +synonym: "SRA binding" EXACT [] +is_a: GO:0003727 ! single-stranded RNA binding +created_by: hjd +creation_date: 2009-11-16T02:18:55Z + +[Term] +id: GO:0002154 +name: thyroid hormone mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of a thyroid hormone." [GOC:hjd] +synonym: "thyroid hormone mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0030522 ! intracellular receptor signaling pathway +created_by: hjd +creation_date: 2009-11-19T12:36:29Z + +[Term] +id: GO:0002155 +name: regulation of thyroid hormone mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway." [GOC:hjd] +synonym: "regulation of thyroid hormone mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002154 ! thyroid hormone mediated signaling pathway +relationship: regulates GO:0002154 ! thyroid hormone mediated signaling pathway +created_by: hjd +creation_date: 2009-11-19T12:37:46Z + +[Term] +id: GO:0002156 +name: negative regulation of thyroid hormone mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway." [GOC:hjd] +synonym: "negative regulation of thyroid hormone mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0002155 ! regulation of thyroid hormone mediated signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002154 ! thyroid hormone mediated signaling pathway +relationship: negatively_regulates GO:0002154 ! thyroid hormone mediated signaling pathway +created_by: hjd +creation_date: 2009-11-19T12:41:48Z + +[Term] +id: GO:0002157 +name: positive regulation of thyroid hormone mediated signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway." [GOC:hjd] +synonym: "positive regulation of thyroid hormone mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0002155 ! regulation of thyroid hormone mediated signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002154 ! thyroid hormone mediated signaling pathway +relationship: positively_regulates GO:0002154 ! thyroid hormone mediated signaling pathway +created_by: hjd +creation_date: 2009-11-19T12:42:57Z + +[Term] +id: GO:0002158 +name: osteoclast proliferation +namespace: biological_process +def: "The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes." [CL:0000092, GOC:hjd] +is_a: GO:0070661 ! leukocyte proliferation +created_by: hjd +creation_date: 2010-02-03T01:50:37Z + +[Term] +id: GO:0002159 +name: desmosome assembly +namespace: biological_process +def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm." [GOC:hjd, ISBN:0198506732] +comment: Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix. +is_a: GO:0002934 ! desmosome organization +is_a: GO:0007043 ! cell-cell junction assembly +created_by: hjd +creation_date: 2010-02-09T10:46:30Z + +[Term] +id: GO:0002160 +name: desmosome maintenance +namespace: biological_process +def: "The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm." [GOC:hjd, ISBN:0198506732] +comment: Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix. +is_a: GO:0002934 ! desmosome organization +is_a: GO:0045217 ! cell-cell junction maintenance +created_by: hjd +creation_date: 2010-02-09T10:50:59Z + +[Term] +id: GO:0002161 +name: aminoacyl-tRNA editing activity +namespace: molecular_function +def: "The hydrolysis of an incorrectly aminoacylated tRNA." [GOC:hjd, PMID:14663147, PMID:16087889] +synonym: "amino acid proofreading activity" RELATED [] +synonym: "aminoacyl-tRNA hydrolysis activity" RELATED [] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0106074 ! aminoacyl-tRNA metabolism involved in translational fidelity +created_by: hjd +creation_date: 2010-02-12T03:06:56Z + +[Term] +id: GO:0002162 +name: dystroglycan binding +namespace: molecular_function +alt_id: GO:0002163 +alt_id: GO:0002166 +def: "Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal)." [GOC:hjd] +synonym: "alpha-dystroglycan binding" NARROW [] +synonym: "beta-dystroglycan binding" NARROW [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: hjd +creation_date: 2010-02-22T02:17:58Z + +[Term] +id: GO:0002164 +name: larval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] +is_a: GO:0007275 ! multicellular organism development +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0002165 +name: instar larval or pupal development +namespace: biological_process +def: "The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster." [GOC:jid, GOC:mtg_sensu] +is_a: GO:0007275 ! multicellular organism development +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0002167 +name: VRK3/VHR/ERK complex +namespace: cellular_component +def: "A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway." [GOC:hjd, PMID:16845380] +is_a: GO:0032991 ! protein-containing complex +created_by: hjd +creation_date: 2010-03-04T01:15:05Z + +[Term] +id: GO:0002168 +name: instar larval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0002164 ! larval development +is_a: GO:0002165 ! instar larval or pupal development + +[Term] +id: GO:0002169 +name: 3-methylcrotonyl-CoA carboxylase complex, mitochondrial +namespace: cellular_component +def: "A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA." [GOC:bf, GOC:hjd, PMID:15868465, PMID:17360195, PMID:22869039] +synonym: "mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme" EXACT [PMID:22869039] +synonym: "mitochondrial MCCC complex" EXACT [GOC:bf] +synonym: "mitochondrial methylcrotonoyl-CoA carboxylase complex" EXACT [GOC:bf] +is_a: GO:0098798 ! mitochondrial protein complex +is_a: GO:1905202 ! methylcrotonoyl-CoA carboxylase complex +created_by: hjd +creation_date: 2010-03-15T04:58:08Z + +[Term] +id: GO:0002170 +name: high-affinity IgA receptor activity +namespace: molecular_function +def: "Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, GOC:signaling] +synonym: "high affinity IgA receptor activity" EXACT [] +is_a: GO:0019766 ! IgA receptor activity +created_by: hjd +creation_date: 2010-05-06T05:00:11Z + +[Term] +id: GO:0002171 +name: low-affinity IgA receptor activity +namespace: molecular_function +def: "Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, GOC:signaling] +synonym: "low affinity IgA receptor activity" EXACT [] +is_a: GO:0019766 ! IgA receptor activity +created_by: hjd +creation_date: 2010-05-06T05:01:41Z + +[Term] +id: GO:0002172 +name: high-affinity IgM receptor activity +namespace: molecular_function +def: "Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, GOC:signaling] +synonym: "high affinity IgM receptor activity" EXACT [] +is_a: GO:0001793 ! IgM receptor activity +created_by: hjd +creation_date: 2010-05-06T05:03:26Z + +[Term] +id: GO:0002173 +name: low-affinity IgM receptor activity +namespace: molecular_function +def: "Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, GOC:signaling] +synonym: "low affinity IgM receptor activity" EXACT [] +is_a: GO:0001793 ! IgM receptor activity +created_by: hjd +creation_date: 2010-05-06T05:04:24Z + +[Term] +id: GO:0002174 +name: mammary stem cell proliferation +namespace: biological_process +def: "The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ." [PMID:15987436] +is_a: GO:0008283 ! cell population proliferation +relationship: part_of GO:0030879 ! mammary gland development +created_by: hjd +creation_date: 2010-09-14T01:19:45Z + +[Term] +id: GO:0002175 +name: protein localization to paranode region of axon +namespace: biological_process +def: "A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon." [PMID:18803321] +synonym: "protein localisation to paranode region of axon" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +is_a: GO:0099612 ! protein localization to axon +created_by: hjd +creation_date: 2010-11-15T10:28:20Z + +[Term] +id: GO:0002176 +name: male germ cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd] +is_a: GO:0036093 ! germ cell proliferation +created_by: hjd +creation_date: 2010-11-18T02:35:14Z + +[Term] +id: GO:0002177 +name: manchette +namespace: cellular_component +def: "A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments." [GOC:krc, PMID:15018141, PMID:22319670, PMID:24440897, PMID:26792866] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0015630 ! microtubule cytoskeleton +created_by: hjd +creation_date: 2010-12-01T02:31:43Z + +[Term] +id: GO:0002178 +name: palmitoyltransferase complex +namespace: cellular_component +def: "A protein complex with palmitoyltransferase activity." [GOC:hjd] +is_a: GO:1990234 ! transferase complex +created_by: hjd +creation_date: 2010-12-03T10:49:17Z + +[Term] +id: GO:0002179 +name: homodimeric serine palmitoyltransferase complex +namespace: cellular_component +def: "A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine." [GOC:hjd] +comment: This complex occurs primarily in bacteria. +is_a: GO:0017059 ! serine C-palmitoyltransferase complex +created_by: hjd +creation_date: 2010-12-03T10:50:59Z + +[Term] +id: GO:0002180 +name: 5-lipoxygenase complex +namespace: cellular_component +def: "An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity." [PMID:19075240] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0031965 ! nuclear membrane +created_by: hjd +creation_date: 2011-06-09T01:05:53Z + +[Term] +id: GO:0002181 +name: cytoplasmic translation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein." [GOC:hjd] +comment: Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms. +subset: goslim_drosophila +subset: goslim_pombe +subset: goslim_yeast +is_a: GO:0006412 ! translation +created_by: hjd +creation_date: 2011-06-09T03:11:53Z + +[Term] +id: GO:0002182 +name: cytoplasmic translational elongation +namespace: biological_process +def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm." [GOC:hjd] +is_a: GO:0006414 ! translational elongation +intersection_of: GO:0006414 ! translational elongation +intersection_of: part_of GO:0002181 ! cytoplasmic translation +relationship: part_of GO:0002181 ! cytoplasmic translation +created_by: hjd +creation_date: 2011-06-09T03:14:42Z + +[Term] +id: GO:0002183 +name: cytoplasmic translational initiation +namespace: biological_process +def: "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [GOC:hjd] +is_a: GO:0006413 ! translational initiation +intersection_of: GO:0006413 ! translational initiation +intersection_of: part_of GO:0002181 ! cytoplasmic translation +relationship: part_of GO:0002181 ! cytoplasmic translation +created_by: hjd +creation_date: 2011-06-09T03:15:48Z + +[Term] +id: GO:0002184 +name: cytoplasmic translational termination +namespace: biological_process +def: "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon." [GOC:hjd] +is_a: GO:0006415 ! translational termination +intersection_of: GO:0006415 ! translational termination +intersection_of: occurs_in GO:0005829 ! cytosol +relationship: occurs_in GO:0005829 ! cytosol +relationship: part_of GO:0002181 ! cytoplasmic translation +created_by: hjd +creation_date: 2011-06-09T03:17:13Z + +[Term] +id: GO:0002185 +name: creatine kinase complex +namespace: cellular_component +def: "A protein complex having creatine kinase activity." [GOC:hjd] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: hjd +creation_date: 2011-06-14T02:12:19Z + +[Term] +id: GO:0002186 +name: cytosolic creatine kinase complex +namespace: cellular_component +def: "A dimeric protein complex having creatine kinase activity." [PMID:173175] +is_a: GO:0002185 ! creatine kinase complex +intersection_of: GO:0002185 ! creatine kinase complex +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol +created_by: hjd +creation_date: 2011-06-14T02:14:16Z + +[Term] +id: GO:0002187 +name: mitochondrial creatine kinase complex +namespace: cellular_component +def: "An octomeric protein complex having creatine kinase activity." [PMID:16236486] +is_a: GO:0002185 ! creatine kinase complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0002185 ! creatine kinase complex +intersection_of: part_of GO:0005739 ! mitochondrion +created_by: hjd +creation_date: 2011-06-14T02:15:29Z + +[Term] +id: GO:0002188 +name: translation reinitiation +namespace: biological_process +def: "A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon." [PMID:18056426, PMID:18765792] +is_a: GO:0002183 ! cytoplasmic translational initiation +created_by: hjd +creation_date: 2011-06-22T12:31:13Z + +[Term] +id: GO:0002189 +name: ribose phosphate diphosphokinase complex +namespace: cellular_component +def: "A protein complex having ribose phosphate diphosphokinase activity." [GO:hjd, PMID:9348095] +comment: In mammals, the complex consists of two non-identical catalytic subunits and two non-identical regulatory subunits. +synonym: "phosphoribosylpyrophosphate synthetase complex" EXACT [PMID:9348095] +synonym: "PRPP synthetase complex" EXACT [PMID:9348095] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: hjd +creation_date: 2011-06-27T02:49:33Z + +[Term] +id: GO:0002190 +name: cap-independent translational initiation +namespace: biological_process +def: "The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation." [PMID:17284590] +is_a: GO:0002183 ! cytoplasmic translational initiation +created_by: hjd +creation_date: 2011-08-11T02:16:05Z + +[Term] +id: GO:0002191 +name: cap-dependent translational initiation +namespace: biological_process +def: "The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation." [PMID:17284590, PMID:19604130] +is_a: GO:0002183 ! cytoplasmic translational initiation +created_by: hjd +creation_date: 2011-08-11T02:20:24Z + +[Term] +id: GO:0002192 +name: IRES-dependent translational initiation of linear mRNA +namespace: biological_process +def: "The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation." [PMID:17284590] +is_a: GO:0110017 ! cap-independent translational initiation of linear mRNA +created_by: hjd +creation_date: 2011-08-11T02:32:45Z + +[Term] +id: GO:0002193 +name: MAML1-RBP-Jkappa- ICN1 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [CORUM:2949, PMID:16510869] +synonym: "MAML1-CSL-ICN1" EXACT [] +synonym: "MAML1-CSL-Notch1 complex" EXACT [] +synonym: "MAML1-RBP-Jkappa-Notch1 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: hjd +creation_date: 2011-08-11T04:08:18Z + +[Term] +id: GO:0002194 +name: hepatocyte cell migration +namespace: biological_process +def: "The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes." [CL:0000182, PMID:9794819] +is_a: GO:0016477 ! cell migration +created_by: hjd +creation_date: 2011-08-30T04:27:39Z + +[Term] +id: GO:0002195 +name: 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs." [UniPathway:UPA00729] +comment: In Salmonella typhimurium, 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A; also referred to as 2-methylthio cis-ribozeatin) is found in tRNA, most likely in the species that have ms2i6A in E. coli. +is_a: GO:0006400 ! tRNA modification +created_by: hjd +creation_date: 2011-08-31T02:20:06Z + +[Term] +id: GO:0002196 +name: Ser-tRNA(Ala) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala)." [GOC:hjd, PMID:21285375] +is_a: GO:0002161 ! aminoacyl-tRNA editing activity +created_by: hjd +creation_date: 2011-09-30T02:18:50Z + +[Term] +id: GO:0002197 +name: xanthine dehydrogenase complex +namespace: cellular_component +def: "A homodimeric protein complex having xanthine dehydrogenase activity." [GOC:hjd, PMID:8224915] +is_a: GO:1990204 ! oxidoreductase complex +created_by: hjd +creation_date: 2011-10-03T03:55:57Z + +[Term] +id: GO:0002198 +name: obsolete S/G2 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. The transition from a cell in the S phase to the G2 phase." [GOC:hjd, GOC:mtg_cell_cycle, PMID:15161931] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "S/G2 transition of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: hjd +creation_date: 2011-11-02T10:36:58Z + +[Term] +id: GO:0002199 +name: zona pellucida receptor complex +namespace: cellular_component +def: "A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction." [GOC:hjd, PMID:21880732] +synonym: "sperm protein complex I" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0005832 ! chaperonin-containing T-complex +created_by: hjd +creation_date: 2011-12-23T01:33:23Z + +[Term] +id: GO:0002200 +name: somatic diversification of immune receptors +namespace: biological_process +def: "The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences." [GOC:add, ISBN:0781735149, PMID:16102575, PMID:16166509] +comment: Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification. +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0002520 ! immune system development + +[Term] +id: GO:0002201 +name: somatic diversification of DSCAM-based immune receptors +namespace: biological_process +def: "The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects." [GOC:add, PMID:16261174] +comment: Note that this type of immune receptor may not be limited to insects. +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002202 +name: somatic diversification of variable lymphocyte receptors of jawless fish +namespace: biological_process +def: "The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish." [GOC:add, PMID:16373579] +comment: Note that jawless fish refers to both lampreys (Petremyzontidae, ncbi_taxonomy_id:7746) and hagfish (Myxinidae, ncbi_taxonomy_id:7762). +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002203 +name: proteolysis by cytosolic proteases associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591] +comment: Note that a separate term covers proteolysis by the proteasome complex (proteasomal proteolysis associated with antigen processing and presentation ; GO:0002497). +is_a: GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002204 +name: somatic recombination of immunoglobulin genes involved in immune response +namespace: biological_process +def: "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response." [GOC:add, ISBN:0781735149] +synonym: "somatic recombination of antibody genes during immune response" RELATED [] +synonym: "somatic recombination of immunoglobulin genes during immune response" RELATED [GOC:dph] +is_a: GO:0002208 ! somatic diversification of immunoglobulins involved in immune response +is_a: GO:0016447 ! somatic recombination of immunoglobulin gene segments + +[Term] +id: GO:0002205 +name: somatic hypermutation of immunoglobulin genes involved in immune response +namespace: biological_process +def: "Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response." [GOC:add, ISBN:0781735149, PMID:11205333, PMID:14991701] +synonym: "somatic hypermutation of antibody genes during immune response" RELATED [] +synonym: "somatic hypermutation of immunoglobulin genes during immune response" RELATED [GOC:dph] +is_a: GO:0002208 ! somatic diversification of immunoglobulins involved in immune response +is_a: GO:0016446 ! somatic hypermutation of immunoglobulin genes +relationship: part_of GO:0002344 ! B cell affinity maturation + +[Term] +id: GO:0002206 +name: gene conversion of immunoglobulin genes +namespace: biological_process +def: "The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion." [GOC:add, PMID:14991701] +synonym: "gene conversion of antibody genes" EXACT [] +is_a: GO:0002565 ! somatic diversification of immune receptors via gene conversion +is_a: GO:0016445 ! somatic diversification of immunoglobulins +is_a: GO:0035822 ! gene conversion + +[Term] +id: GO:0002207 +name: gene conversion of immunoglobulin genes involved in immune response +namespace: biological_process +def: "The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response." [GOC:add, PMID:14991701] +synonym: "gene conversion of antibody genes during immune response" RELATED [] +synonym: "gene conversion of immunoglobulin genes during immune response" RELATED [GOC:dph] +is_a: GO:0002206 ! gene conversion of immunoglobulin genes +is_a: GO:0002208 ! somatic diversification of immunoglobulins involved in immune response + +[Term] +id: GO:0002208 +name: somatic diversification of immunoglobulins involved in immune response +namespace: biological_process +def: "The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response." [GOC:add, ISBN:0781735149, PMID:14991701] +synonym: "somatic diversification of antibodies during immune response" RELATED [] +synonym: "somatic diversification of immunoglobulins during immune response" RELATED [GOC:dph] +is_a: GO:0016445 ! somatic diversification of immunoglobulins +relationship: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response + +[Term] +id: GO:0002209 +name: behavioral defense response +namespace: biological_process +def: "A behavioral response seeking to protect an organism from an a perceived external threat to that organism." [GO_REF:0000022, GOC:add] +synonym: "behavioural defense response" EXACT [] +is_a: GO:0006952 ! defense response +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0002210 +name: behavioral response to wounding +namespace: biological_process +def: "A behavioral response resulting from wounding." [GO_REF:0000022, GOC:add] +synonym: "behavioural response to wounding" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0009611 ! response to wounding + +[Term] +id: GO:0002211 +name: behavioral defense response to insect +namespace: biological_process +def: "A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism." [GOC:add] +synonym: "behavioural defense response to insect" EXACT [] +is_a: GO:0002209 ! behavioral defense response +is_a: GO:0002213 ! defense response to insect + +[Term] +id: GO:0002212 +name: behavioral defense response to nematode +namespace: biological_process +def: "A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism." [GOC:add, PMID:14506883] +synonym: "behavioural defense response to nematode" EXACT [] +is_a: GO:0002209 ! behavioral defense response +is_a: GO:0002215 ! defense response to nematode + +[Term] +id: GO:0002213 +name: defense response to insect +namespace: biological_process +alt_id: GO:0002214 +def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] +synonym: "physiological defense response to insect" EXACT [] +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0002215 +name: defense response to nematode +namespace: biological_process +alt_id: GO:0002216 +def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883] +synonym: "physiological defense response to nematode" EXACT [] +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0002218 +name: activation of innate immune response +namespace: biological_process +alt_id: GO:0002219 +def: "Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species." [GO_REF:0000022, GOC:add, GOC:mtg_sensu, ISBN:0781735149, PMID:15199967, PMID:16177805] +is_a: GO:0002253 ! activation of immune response +is_a: GO:0045089 ! positive regulation of innate immune response + +[Term] +id: GO:0002220 +name: innate immune response activating cell surface receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor." [GOC:add, ISBN:0781735149, PMID:15199967] +synonym: "activation of innate immune response by cell surface receptor signaling pathway" EXACT [] +synonym: "innate immune response activating cell surface receptor signalling pathway" EXACT [] +is_a: GO:0002429 ! immune response-activating cell surface receptor signaling pathway +is_a: GO:0002758 ! innate immune response-activating signal transduction + +[Term] +id: GO:0002221 +name: pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells." [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967] +synonym: "PAMP receptor signaling pathway" EXACT [ISBN:0781735149, PMID:15199967, PMID:15728447] +synonym: "pathogen receptor signaling pathway" EXACT [ISBN:0781735149, PMID:15199967, PMID:15728447] +synonym: "pathogen receptor signalling pathway" EXACT [ISBN:0781735149, PMID:15199967, PMID:15728447] +synonym: "PRR signaling pathway" EXACT [ISBN:0781735149, PMID:15199967, PMID:15728447] +is_a: GO:0007165 ! signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18588 xsd:anyURI + +[Term] +id: GO:0002222 +name: stimulatory killer cell immunoglobulin-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "stimulatory killer cell immunoglobulin-like receptor signalling pathway" EXACT [] +synonym: "stimulatory KIR signaling pathway" EXACT [ISBN:0781735149] +is_a: GO:0002220 ! innate immune response activating cell surface receptor signaling pathway + +[Term] +id: GO:0002223 +name: stimulatory C-type lectin receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "stimulatory C-type lectin receptor signalling pathway" EXACT [] +synonym: "stimulatory Ly49 family receptor signaling pathway" NARROW [ISBN:0781735149] +is_a: GO:0002220 ! innate immune response activating cell surface receptor signaling pathway + +[Term] +id: GO:0002224 +name: toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] +comment: Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses. +synonym: "TLR signaling pathway" EXACT [ISBN:0781735149] +synonym: "toll-like receptor signalling pathway" EXACT [] +is_a: GO:0002221 ! pattern recognition receptor signaling pathway + +[Term] +id: GO:0002225 +name: positive regulation of antimicrobial peptide production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production." [GOC:add, PMID:11807545] +synonym: "activation of antimicrobial peptide production" NARROW [] +synonym: "antimicrobial peptide induction" EXACT [] +synonym: "stimulation of antimicrobial peptide production" NARROW [] +synonym: "up regulation of antimicrobial peptide production" EXACT [] +synonym: "up-regulation of antimicrobial peptide production" EXACT [] +synonym: "upregulation of antimicrobial peptide production" EXACT [] +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +is_a: GO:0002760 ! positive regulation of antimicrobial humoral response +is_a: GO:0002784 ! regulation of antimicrobial peptide production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002775 ! antimicrobial peptide production +relationship: positively_regulates GO:0002775 ! antimicrobial peptide production + +[Term] +id: GO:0002227 +name: innate immune response in mucosa +namespace: biological_process +def: "Any process of the innate immune response that takes place in the mucosal tissues." [GOC:add, PMID:10719665, PMID:15971105] +is_a: GO:0002385 ! mucosal immune response +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0002228 +name: natural killer cell mediated immunity +namespace: biological_process +def: "The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "NK cell mediated immunity" EXACT [] +is_a: GO:0002449 ! lymphocyte mediated immunity +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0002229 +name: defense response to oomycetes +namespace: biological_process +def: "Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism." [GOC:add, PMID:16497589] +is_a: GO:0002239 ! response to oomycetes +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0002230 +name: positive regulation of defense response to virus by host +namespace: biological_process +def: "Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] +synonym: "activation of antiviral response by host" NARROW [] +synonym: "positive regulation of antiviral response by host" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of antiviral response by host" NARROW [] +synonym: "up regulation of antiviral response by host" EXACT [] +synonym: "up-regulation of antiviral response by host" EXACT [] +synonym: "upregulation of antiviral response by host" EXACT [] +is_a: GO:0050691 ! regulation of defense response to virus by host + +[Term] +id: GO:0002231 +name: detection of oomycetes +namespace: biological_process +def: "The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal." [GOC:add, PMID:15922649] +is_a: GO:0002239 ! response to oomycetes +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0002232 +name: leukocyte chemotaxis involved in inflammatory response +namespace: biological_process +def: "The movement of an immune cell in response to an external stimulus contributing to an inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "immune cell chemotaxis during inflammatory response" RELATED [] +synonym: "leucocyte chemotaxis during inflammatory response" RELATED [] +synonym: "leukocyte chemotaxis during inflammatory response" RELATED [GOC:dph] +is_a: GO:0002523 ! leukocyte migration involved in inflammatory response +is_a: GO:0030595 ! leukocyte chemotaxis +intersection_of: GO:0030595 ! leukocyte chemotaxis +intersection_of: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002233 +name: leukocyte chemotaxis involved in immune response +namespace: biological_process +def: "The movement of an immune cell in response to an external stimulus a part of an immune response." [GOC:add, ISBN:0781735149] +synonym: "immune cell chemotaxis during immune response" EXACT [] +synonym: "leucocyte chemotaxis during immune response" EXACT [] +is_a: GO:0002522 ! leukocyte migration involved in immune response +is_a: GO:0030595 ! leukocyte chemotaxis +intersection_of: GO:0030595 ! leukocyte chemotaxis +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002234 +name: detection of endoplasmic reticulum overloading +namespace: biological_process +def: "The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal." [GOC:add, PMID:10390516] +synonym: "detection of ER overloading" EXACT [] +is_a: GO:0006983 ! ER overload response +is_a: GO:0009595 ! detection of biotic stimulus + +[Term] +id: GO:0002235 +name: detection of unfolded protein +namespace: biological_process +def: "The series of events in which an unfolded protein stimulus is received and converted into a molecular signal." [GOC:add, PMID:15226511, PMID:7765470] +is_a: GO:0006986 ! response to unfolded protein +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0002236 +name: detection of misfolded protein +namespace: biological_process +def: "The series of events in which a misfolded protein stimulus is received and converted into a molecular signal." [GOC:add, PMID:15226511] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0051788 ! response to misfolded protein + +[Term] +id: GO:0002237 +name: response to molecule of bacterial origin +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin." [GOC:rl, GOC:sm] +synonym: "response to bacteria associated molecule" EXACT [] +synonym: "response to bacterial associated molecule" EXACT [] +synonym: "response to bacterium associated molecule" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0043207 ! response to external biotic stimulus +relationship: part_of GO:0009617 ! response to bacterium + +[Term] +id: GO:0002238 +name: response to molecule of fungal origin +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide." [GOC:rl, GOC:sm] +synonym: "response to fungus associated molecule" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0043207 ! response to external biotic stimulus +relationship: part_of GO:0009620 ! response to fungus + +[Term] +id: GO:0002239 +name: response to oomycetes +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes." [GOC:add, PMID:16497589] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0002240 +name: response to molecule of oomycetes origin +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin." [GOC:rl, GOC:sm] +synonym: "response to oomycetes associated molecule" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0043207 ! response to external biotic stimulus +relationship: part_of GO:0002239 ! response to oomycetes + +[Term] +id: GO:0002241 +name: response to parasitic plant +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant." [GOC:add, PMID:16547862] +is_a: GO:0009608 ! response to symbiont + +[Term] +id: GO:0002242 +name: defense response to parasitic plant +namespace: biological_process +def: "Reactions triggered in response to the presence of a parasitic plant that act to protect an organism." [GOC:add] +is_a: GO:0002241 ! response to parasitic plant +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0002243 +name: detection of parasitic plant +namespace: biological_process +def: "The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal." [GOC:add, PMID:16547862] +is_a: GO:0002241 ! response to parasitic plant +is_a: GO:0009602 ! detection of symbiont + +[Term] +id: GO:0002244 +name: hematopoietic progenitor cell differentiation +namespace: biological_process +def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] +synonym: "haematopoietic progenitor cell differentiation" EXACT [] +synonym: "haemopoietic progenitor cell differentiation" EXACT [] +synonym: "hemopoietic progenitor cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030097 ! hemopoiesis + +[Term] +id: GO:0002246 +name: wound healing involved in inflammatory response +namespace: biological_process +def: "The series of events that restore integrity to damaged tissue that contribute to an inflammatory response." [GOC:jal, ISBN:0721601871] +synonym: "healing during inflammatory response" RELATED [GOC:dph] +synonym: "inflammatory response wound healing" RELATED [GOC:dph] +is_a: GO:0042060 ! wound healing +intersection_of: GO:0042060 ! wound healing +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0090594 ! inflammatory response to wounding + +[Term] +id: GO:0002247 +name: clearance of damaged tissue involved in inflammatory response wound healing +namespace: biological_process +def: "The series of events leading to removal of necrotic debris that contribute to an inflammatory response." [GOC:jal, ISBN:0721601871] +synonym: "clearance of damaged tissue during inflammatory response" RELATED [GOC:dph] +is_a: GO:0048771 ! tissue remodeling +relationship: part_of GO:0002246 ! wound healing involved in inflammatory response + +[Term] +id: GO:0002248 +name: connective tissue replacement involved in inflammatory response wound healing +namespace: biological_process +def: "The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response." [GOC:jal, ISBN:0721601871] +synonym: "connective tissue replacement during inflammatory response" RELATED [GOC:dph] +synonym: "fibrosis during inflammatory response" NARROW [ISBN:0721601871] +is_a: GO:0097709 ! connective tissue replacement +relationship: part_of GO:0002246 ! wound healing involved in inflammatory response + +[Term] +id: GO:0002249 +name: lymphocyte anergy +namespace: biological_process +def: "Any process contributing to lymphocyte anergy, a state of functional inactivation." [GOC:add] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002250 +name: adaptive immune response +namespace: biological_process +def: "An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "acquired immune response" EXACT [ISBN:068340007X] +synonym: "immune memory response" EXACT [GOC:add] +xref: Wikipedia:Adaptive_immune_system +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0002251 +name: organ or tissue specific immune response +namespace: biological_process +def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal] +synonym: "immune response in organ or tissue" EXACT [] +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0002252 +name: immune effector process +namespace: biological_process +def: "Any process of the immune system that can potentially contribute to an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002376 ! immune system process + +[Term] +id: GO:0002253 +name: activation of immune response +namespace: biological_process +def: "Any process that initiates an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002376 ! immune system process +is_a: GO:0050778 ! positive regulation of immune response + +[Term] +id: GO:0002254 +name: kinin cascade +namespace: biological_process +def: "A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability." [GOC:jal, ISBN:0721601871, PMID:11842287, PMID:14501145] +is_a: GO:0002526 ! acute inflammatory response +is_a: GO:0072376 ! protein activation cascade + +[Term] +id: GO:0002255 +name: tissue kallikrein-kinin cascade +namespace: biological_process +def: "A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability." [GOC:add, PMID:11842287, PMID:14501145] +synonym: "glandular kallikrein-kinin cascade" EXACT [] +is_a: GO:0002254 ! kinin cascade + +[Term] +id: GO:0002256 +name: regulation of kinin cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the kinin cascade." [GOC:jal] +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002254 ! kinin cascade +relationship: regulates GO:0002254 ! kinin cascade + +[Term] +id: GO:0002257 +name: negative regulation of kinin cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade." [GOC:jal] +synonym: "down regulation of kinin cascade" EXACT [] +synonym: "down-regulation of kinin cascade" EXACT [] +synonym: "downregulation of kinin cascade" EXACT [] +synonym: "inhibition of kinin cascade" NARROW [] +is_a: GO:0002256 ! regulation of kinin cascade +is_a: GO:0002674 ! negative regulation of acute inflammatory response +is_a: GO:2000258 ! negative regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002254 ! kinin cascade +relationship: negatively_regulates GO:0002254 ! kinin cascade + +[Term] +id: GO:0002258 +name: positive regulation of kinin cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the kinin cascade." [GOC:jal] +synonym: "activation of kinin cascade" NARROW [] +synonym: "stimulation of kinin cascade" NARROW [] +synonym: "up regulation of kinin cascade" EXACT [] +synonym: "up-regulation of kinin cascade" EXACT [] +synonym: "upregulation of kinin cascade" EXACT [] +is_a: GO:0002256 ! regulation of kinin cascade +is_a: GO:0002675 ! positive regulation of acute inflammatory response +is_a: GO:2000259 ! positive regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002254 ! kinin cascade +relationship: positively_regulates GO:0002254 ! kinin cascade + +[Term] +id: GO:0002259 +name: endothelial cell activation within high endothelial venule involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "endothelial cell activation within high endothelial venule during immune response" RELATED [GOC:tb] +is_a: GO:0002264 ! endothelial cell activation involved in immune response + +[Term] +id: GO:0002260 +name: lymphocyte homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262] +is_a: GO:0001776 ! leukocyte homeostasis + +[Term] +id: GO:0002261 +name: mucosal lymphocyte homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15609020] +is_a: GO:0002260 ! lymphocyte homeostasis + +[Term] +id: GO:0002262 +name: myeloid cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add] +is_a: GO:0002376 ! immune system process +is_a: GO:0048872 ! homeostasis of number of cells + +[Term] +id: GO:0002263 +name: cell activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0001775 ! cell activation +is_a: GO:0002252 ! immune effector process +intersection_of: GO:0001775 ! cell activation +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002264 +name: endothelial cell activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "endothelial cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002263 ! cell activation involved in immune response +is_a: GO:0042118 ! endothelial cell activation +intersection_of: GO:0042118 ! endothelial cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002265 +name: astrocyte activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:11138785] +synonym: "astrocyte activation during immune response" RELATED [GOC:tb] +is_a: GO:0002263 ! cell activation involved in immune response +is_a: GO:0048143 ! astrocyte activation +intersection_of: GO:0048143 ! astrocyte activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002266 +name: follicular dendritic cell activation +namespace: biological_process +def: "A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, PMID:15606789] +is_a: GO:0001775 ! cell activation + +[Term] +id: GO:0002267 +name: follicular dendritic cell activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15606789] +synonym: "follicular dendritic cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002263 ! cell activation involved in immune response +is_a: GO:0002266 ! follicular dendritic cell activation +intersection_of: GO:0002266 ! follicular dendritic cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002268 +name: follicular dendritic cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell." [GOC:add, ISBN:0781735149] +is_a: GO:0002266 ! follicular dendritic cell activation +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0002269 +name: leukocyte activation involved in inflammatory response +namespace: biological_process +def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "immune cell activation during inflammatory response" RELATED [] +synonym: "leukocyte activation during inflammatory response" RELATED [GOC:tb] +is_a: GO:0045321 ! leukocyte activation +intersection_of: GO:0045321 ! leukocyte activation +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002270 +name: plasmacytoid dendritic cell activation +namespace: biological_process +def: "A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, PMID:15990333, PMID:16174109] +is_a: GO:0045321 ! leukocyte activation + +[Term] +id: GO:0002271 +name: plasmacytoid dendritic cell activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15990333, PMID:16174109] +synonym: "plasmacytoid dendritic cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002270 ! plasmacytoid dendritic cell activation +is_a: GO:0002366 ! leukocyte activation involved in immune response +intersection_of: GO:0002270 ! plasmacytoid dendritic cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002272 +name: plasmacytoid dendritic cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response." [GOC:add, PMID:15990333] +synonym: "plasmacytoid dendritic cell differentiation during immune response" RELATED [GOC:dph] +is_a: GO:0002271 ! plasmacytoid dendritic cell activation involved in immune response +is_a: GO:0002273 ! plasmacytoid dendritic cell differentiation +intersection_of: GO:0002273 ! plasmacytoid dendritic cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002273 +name: plasmacytoid dendritic cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell." [GOC:add, PMID:15990333, PMID:16174108] +is_a: GO:0002270 ! plasmacytoid dendritic cell activation +is_a: GO:0097028 ! dendritic cell differentiation + +[Term] +id: GO:0002274 +name: myeloid leukocyte activation +namespace: biological_process +def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] +synonym: "myeloid leucocyte activation" EXACT [] +is_a: GO:0045321 ! leukocyte activation + +[Term] +id: GO:0002275 +name: myeloid cell activation involved in immune response +namespace: biological_process +def: "A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "myeloid cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002274 ! myeloid leukocyte activation +is_a: GO:0002366 ! leukocyte activation involved in immune response + +[Term] +id: GO:0002276 +name: basophil activation involved in immune response +namespace: biological_process +def: "A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "basophil activation during immune response" RELATED [GOC:tb] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0045575 ! basophil activation +intersection_of: GO:0045575 ! basophil activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002277 +name: myeloid dendritic cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "myeloid dendritic cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0001773 ! myeloid dendritic cell activation +is_a: GO:0002275 ! myeloid cell activation involved in immune response +intersection_of: GO:0001773 ! myeloid dendritic cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002278 +name: eosinophil activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "eosinophil activation during immune response" RELATED [GOC:tb] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0043307 ! eosinophil activation +intersection_of: GO:0043307 ! eosinophil activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002279 +name: mast cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "mast cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0045576 ! mast cell activation +intersection_of: GO:0045576 ! mast cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002280 +name: monocyte activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149, PMID:16551245] +synonym: "monocyte activation during immune response" RELATED [GOC:tb] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0042117 ! monocyte activation +intersection_of: GO:0042117 ! monocyte activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002281 +name: macrophage activation involved in immune response +namespace: biological_process +def: "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "macrophage activation during immune response" RELATED [GOC:tb] +synonym: "macrophage polarization involved in immune response" EXACT [] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0042116 ! macrophage activation +intersection_of: GO:0042116 ! macrophage activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002282 +name: microglial cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "microglial cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0001774 ! microglial cell activation +is_a: GO:0002281 ! macrophage activation involved in immune response +intersection_of: GO:0001774 ! microglial cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002283 +name: neutrophil activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "neutrophil activation during immune response" RELATED [GOC:tb] +is_a: GO:0002275 ! myeloid cell activation involved in immune response +is_a: GO:0042119 ! neutrophil activation +intersection_of: GO:0042119 ! neutrophil activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002284 +name: myeloid dendritic cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response." [GOC:add, ISBN:0781735149] +synonym: "myeloid dendritic cell differentiation during immune response" RELATED [GOC:tb] +is_a: GO:0002277 ! myeloid dendritic cell activation involved in immune response +is_a: GO:0043011 ! myeloid dendritic cell differentiation +intersection_of: GO:0043011 ! myeloid dendritic cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002285 +name: lymphocyte activation involved in immune response +namespace: biological_process +def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "lymphocyte activation during immune response" RELATED [GOC:tb] +is_a: GO:0002366 ! leukocyte activation involved in immune response +is_a: GO:0046649 ! lymphocyte activation +intersection_of: GO:0046649 ! lymphocyte activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002286 +name: T cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "T cell activation during immune response" RELATED [GOC:tb] +synonym: "T lymphocyte activation during immune response" RELATED [] +synonym: "T-cell activation during immune response" RELATED [] +synonym: "T-lymphocyte activation during immune response" RELATED [] +is_a: GO:0002285 ! lymphocyte activation involved in immune response +is_a: GO:0042110 ! T cell activation +intersection_of: GO:0042110 ! T cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002287 +name: alpha-beta T cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "alpha-beta T cell activation during immune response" RELATED [GOC:tb] +synonym: "alpha-beta T lymphocyte activation during immune response" RELATED [] +synonym: "alpha-beta T-cell activation during immune response" RELATED [] +synonym: "alpha-beta T-lymphocyte activation during immune response" RELATED [] +is_a: GO:0002286 ! T cell activation involved in immune response +is_a: GO:0046631 ! alpha-beta T cell activation +intersection_of: GO:0046631 ! alpha-beta T cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002288 +name: NK T cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15771592] +synonym: "natural killer T lymphocyte activation during immune response" RELATED [] +synonym: "natural killer T-cell activation during immune response" RELATED [] +synonym: "natural killer T-lymphocyte activation during immune response" RELATED [] +synonym: "NK T cell activation during immune response" RELATED [GOC:tb] +synonym: "NK T lymphocyte activation during immune response" RELATED [] +synonym: "NK T-cell activation during immune response" RELATED [] +synonym: "NK T-lymphocyte activation during immune response" RELATED [] +is_a: GO:0002287 ! alpha-beta T cell activation involved in immune response +is_a: GO:0051132 ! NK T cell activation +intersection_of: GO:0051132 ! NK T cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002289 +name: NK T cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of a NK T cell population by cell division as part of an immune response." [GOC:add, PMID:15771592] +synonym: "natural killer T lymphocyte proliferation during immune response" RELATED [] +synonym: "natural killer T-cell proliferation during immune response" RELATED [] +synonym: "natural killer T-lymphocyte proliferation during immune response" RELATED [] +synonym: "NK T cell proliferation during immune response" RELATED [GOC:tb] +synonym: "NK T lymphocyte proliferation during immune response" RELATED [] +synonym: "NK T-cell proliferation during immune response" RELATED [] +synonym: "NK T-lymphocyte proliferation during immune response" RELATED [] +is_a: GO:0001866 ! NK T cell proliferation +is_a: GO:0002288 ! NK T cell activation involved in immune response +is_a: GO:0002310 ! alpha-beta T cell proliferation involved in immune response +intersection_of: GO:0001866 ! NK T cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002290 +name: gamma-delta T cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:8717523] +synonym: "gamma-delta T cell activation during immune response" RELATED [GOC:tb] +synonym: "gamma-delta T lymphocyte activation during immune response" RELATED [] +synonym: "gamma-delta T-cell activation during immune response" RELATED [] +synonym: "gamma-delta T-lymphocyte activation during immune response" RELATED [] +is_a: GO:0002286 ! T cell activation involved in immune response +is_a: GO:0046629 ! gamma-delta T cell activation +intersection_of: GO:0046629 ! gamma-delta T cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002291 +name: T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [] +synonym: "T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [] +synonym: "T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [] +is_a: GO:0002286 ! T cell activation involved in immune response + +[Term] +id: GO:0002292 +name: T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T cell development involved in immune response" RELATED [GOC:add] +synonym: "T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "T lymphocyte differentiation during immune response" RELATED [] +synonym: "T-cell differentiation during immune response" RELATED [] +synonym: "T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002286 ! T cell activation involved in immune response +is_a: GO:0030217 ! T cell differentiation +intersection_of: GO:0030217 ! T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002293 +name: alpha-beta T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "alpha-beta T cell development involved in immune response" RELATED [GOC:add] +synonym: "alpha-beta T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "alpha-beta T lymphocyte differentiation during immune response" RELATED [] +synonym: "alpha-beta T-cell differentiation during immune response" RELATED [] +synonym: "alpha-beta T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002287 ! alpha-beta T cell activation involved in immune response +is_a: GO:0002292 ! T cell differentiation involved in immune response +is_a: GO:0046632 ! alpha-beta T cell differentiation +intersection_of: GO:0046632 ! alpha-beta T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002294 +name: CD4-positive, alpha-beta T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, alpha-beta T cell development involved in immune response" RELATED [GOC:add] +synonym: "CD4-positive, alpha-beta T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "CD4-positive, alpha-beta T lymphocyte differentiation during immune response" RELATED [] +synonym: "CD4-positive, alpha-beta T-cell differentiation during immune response" RELATED [] +synonym: "CD4-positive, alpha-beta T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002293 ! alpha-beta T cell differentiation involved in immune response +is_a: GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +intersection_of: GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002295 +name: T-helper cell lineage commitment +namespace: biological_process +def: "The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes." [GOC:add, ISBN:0781735149] +synonym: "T-helper cell fate commitment" EXACT [] +synonym: "Th0 lineage commitment" RELATED [ISBN:0781735149] +synonym: "Thp lineage commitment" RELATED [ISBN:0781735149] +is_a: GO:0043373 ! CD4-positive, alpha-beta T cell lineage commitment +relationship: part_of GO:0042093 ! T-helper cell differentiation + +[Term] +id: GO:0002296 +name: T-helper 1 cell lineage commitment +namespace: biological_process +def: "The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis." [GOC:add, ISBN:0781735149] +synonym: "T-helper 1 cell fate commitment" EXACT [ISBN:0781735149] +synonym: "Th1 cell lineage commitment" EXACT [ISBN:0781735149] +synonym: "Th1 fate commitment" EXACT [ISBN:0781735149] +is_a: GO:0002295 ! T-helper cell lineage commitment +relationship: part_of GO:0045063 ! T-helper 1 cell differentiation + +[Term] +id: GO:0002297 +name: T-helper 2 cell lineage commitment +namespace: biological_process +def: "The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy." [GOC:add, ISBN:0781735149] +synonym: "T-helper 2 cell fate commitment" EXACT [ISBN:0781735149] +synonym: "Th2 fate commitment" EXACT [ISBN:0781735149] +is_a: GO:0002295 ! T-helper cell lineage commitment +relationship: part_of GO:0045064 ! T-helper 2 cell differentiation + +[Term] +id: GO:0002298 +name: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response." [GOC:add, PMID:12093005] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" RELATED [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" RELATED [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" RELATED [] +synonym: "CD4-positive, CD25-positive, alpha-beta T cell development involved in immune response" RELATED [GOC:add] +is_a: GO:0002294 ! CD4-positive, alpha-beta T cell differentiation involved in immune response +is_a: GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +intersection_of: GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002299 +name: alpha-beta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "alpha-beta intraepithelial T cell development" RELATED [GOC:add] +synonym: "alpha-beta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "alpha-beta intraepithelial T-cell differentiation" EXACT [] +synonym: "alpha-beta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0002300 +name: CD8-positive, alpha-beta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, alpha-beta intraepithelial T cell development" RELATED [GOC:add] +synonym: "CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta intraepithelial T-cell differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0002299 ! alpha-beta intraepithelial T cell differentiation +is_a: GO:0043374 ! CD8-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0002301 +name: CD4-positive, alpha-beta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, alpha-beta intraepithelial T cell development" RELATED [GOC:add] +synonym: "CD4-positive, alpha-beta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "CD4-positive, alpha-beta intraepithelial T-cell differentiation" EXACT [] +synonym: "CD4-positive, alpha-beta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0002299 ! alpha-beta intraepithelial T cell differentiation +is_a: GO:0043367 ! CD4-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0002302 +name: CD8-positive, alpha-beta T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, alpha-beta intraepithelial T cell development" RELATED [GOC:add] +synonym: "CD8-positive, alpha-beta T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "CD8-positive, alpha-beta T lymphocyte differentiation during immune response" RELATED [] +synonym: "CD8-positive, alpha-beta T-cell differentiation during immune response" RELATED [] +synonym: "CD8-positive, alpha-beta T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002293 ! alpha-beta T cell differentiation involved in immune response +is_a: GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +intersection_of: GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002303 +name: gamma-delta T cell differentiation involved in immune response +namespace: biological_process +def: "The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "gamma-delta T cell development involved in immune response" RELATED [GOC:add] +synonym: "gamma-delta T cell differentiation during immune response" RELATED [GOC:dph] +synonym: "gamma-delta T lymphocyte differentiation during immune response" RELATED [] +synonym: "gamma-delta T-cell differentiation during immune response" RELATED [] +synonym: "gamma-delta T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002290 ! gamma-delta T cell activation involved in immune response +is_a: GO:0002292 ! T cell differentiation involved in immune response +is_a: GO:0042492 ! gamma-delta T cell differentiation +intersection_of: GO:0042492 ! gamma-delta T cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002304 +name: gamma-delta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "gamma-delta intraepithelial T cell development" RELATED [GOC:add] +synonym: "gamma-delta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "gamma-delta intraepithelial T-cell differentiation" EXACT [] +synonym: "gamma-delta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0042492 ! gamma-delta T cell differentiation + +[Term] +id: GO:0002305 +name: CD8-positive, gamma-delta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, gamma-delta intraepithelial T cell development" RELATED [GOC:add] +synonym: "CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "CD8-positive, gamma-delta intraepithelial T-cell differentiation" EXACT [] +synonym: "CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0002304 ! gamma-delta intraepithelial T cell differentiation + +[Term] +id: GO:0002306 +name: CD4-positive gamma-delta intraepithelial T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, gamma-delta intraepithelial T cell development" RELATED [GOC:add] +synonym: "CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation" EXACT [] +synonym: "CD4-positive, gamma-delta intraepithelial T-cell differentiation" EXACT [] +synonym: "CD4-positive, gamma-delta intraepithelial T-lymphocyte differentiation" EXACT [] +is_a: GO:0002304 ! gamma-delta intraepithelial T cell differentiation + +[Term] +id: GO:0002307 +name: CD8-positive, alpha-beta regulatory T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, alpha-beta regulatory T cell development" RELATED [GOC:add] +synonym: "CD8-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta regulatory T-cell differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] +is_a: GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +is_a: GO:0045066 ! regulatory T cell differentiation + +[Term] +id: GO:0002308 +name: CD8-positive, alpha-beta cytotoxic T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, alpha-beta cytotoxic T cell development" RELATED [GOC:add] +synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta cytotoxic T-cell differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta cytotoxic T-lymphocyte differentiation" EXACT [] +is_a: GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +is_a: GO:0045065 ! cytotoxic T cell differentiation + +[Term] +id: GO:0002309 +name: T cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] +synonym: "T cell proliferation during immune response" RELATED [GOC:tb] +synonym: "T lymphocyte proliferation during immune response" RELATED [] +synonym: "T-cell proliferation during immune response" RELATED [] +synonym: "T-lymphocyte proliferation during immune response" RELATED [] +is_a: GO:0002286 ! T cell activation involved in immune response +is_a: GO:0042098 ! T cell proliferation +intersection_of: GO:0042098 ! T cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002310 +name: alpha-beta T cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of an alpha-beta T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] +synonym: "alpha-beta T cell proliferation during immune response" RELATED [GOC:tb] +synonym: "alpha-beta T lymphocyte proliferation during immune response" RELATED [] +synonym: "alpha-beta T-cell proliferation during immune response" RELATED [] +synonym: "alpha-beta T-lymphocyte proliferation during immune response" RELATED [] +is_a: GO:0002287 ! alpha-beta T cell activation involved in immune response +is_a: GO:0002309 ! T cell proliferation involved in immune response +is_a: GO:0046633 ! alpha-beta T cell proliferation +intersection_of: GO:0046633 ! alpha-beta T cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002311 +name: gamma-delta T cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of a gamma-delta T cell population by cell division as part of an immune response." [GOC:add] +synonym: "gamma-delta T cell proliferation during immune response" RELATED [GOC:tb] +synonym: "gamma-delta T lymphocyte proliferation during immune response" RELATED [] +synonym: "gamma-delta T-cell proliferation during immune response" RELATED [] +synonym: "gamma-delta T-lymphocyte proliferation during immune response" RELATED [] +is_a: GO:0002290 ! gamma-delta T cell activation involved in immune response +is_a: GO:0002309 ! T cell proliferation involved in immune response +is_a: GO:0046630 ! gamma-delta T cell proliferation +intersection_of: GO:0046630 ! gamma-delta T cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002312 +name: B cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:jal] +synonym: "B cell activation during immune response" RELATED [GOC:tb] +synonym: "B lymphocyte activation during immune response" RELATED [] +synonym: "B-cell activation during immune response" RELATED [] +synonym: "B-lymphocyte activation during immune response" RELATED [] +is_a: GO:0002285 ! lymphocyte activation involved in immune response +is_a: GO:0042113 ! B cell activation +intersection_of: GO:0042113 ! B cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002313 +name: mature B cell differentiation involved in immune response +namespace: biological_process +def: "The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response." [GOC:jal] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "mature B cell development involved in immune response" RELATED [GOC:add] +synonym: "mature B cell differentiation during immune response" RELATED [GOC:tb] +synonym: "mature B lymphocyte differentiation during immune response" RELATED [] +synonym: "mature B-cell differentiation during immune response" RELATED [] +synonym: "mature B-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002312 ! B cell activation involved in immune response +is_a: GO:0002335 ! mature B cell differentiation +intersection_of: GO:0002335 ! mature B cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002314 +name: germinal center B cell differentiation +namespace: biological_process +def: "The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA)." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "germinal center B cell development" RELATED [GOC:add] +synonym: "germinal center B lymphocyte differentiation" EXACT [] +synonym: "germinal center B-cell differentiation" EXACT [] +synonym: "germinal center B-lymphocyte differentiation" EXACT [] +is_a: GO:0002313 ! mature B cell differentiation involved in immune response + +[Term] +id: GO:0002315 +name: marginal zone B cell differentiation +namespace: biological_process +def: "The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL)." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "marginal zone B cell development" RELATED [GOC:add] +synonym: "marginal zone B lymphocyte differentiation" EXACT [] +synonym: "marginal zone B-cell differentiation" EXACT [] +synonym: "marginal zone B-lymphocyte differentiation" EXACT [] +is_a: GO:0002313 ! mature B cell differentiation involved in immune response + +[Term] +id: GO:0002316 +name: follicular B cell differentiation +namespace: biological_process +def: "The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "follicular B cell development" RELATED [GOC:add] +synonym: "follicular B lymphocyte differentiation" EXACT [] +synonym: "follicular B-cell differentiation" EXACT [] +synonym: "follicular B-lymphocyte differentiation" EXACT [] +is_a: GO:0002313 ! mature B cell differentiation involved in immune response + +[Term] +id: GO:0002317 +name: plasma cell differentiation +namespace: biological_process +def: "The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody." [GOC:jal] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "plasma cell development" RELATED [GOC:add] +is_a: GO:0002313 ! mature B cell differentiation involved in immune response + +[Term] +id: GO:0002318 +name: myeloid progenitor cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264] +is_a: GO:0002244 ! hematopoietic progenitor cell differentiation + +[Term] +id: GO:0002319 +name: memory B cell differentiation +namespace: biological_process +def: "The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "memory B cell development" RELATED [GOC:add] +synonym: "memory B lymphocyte differentiation" EXACT [] +synonym: "memory B-cell differentiation" EXACT [] +synonym: "memory B-lymphocyte differentiation" EXACT [] +is_a: GO:0002313 ! mature B cell differentiation involved in immune response +is_a: GO:0090715 ! immunological memory formation process + +[Term] +id: GO:0002320 +name: lymphoid progenitor cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264] +is_a: GO:0002244 ! hematopoietic progenitor cell differentiation + +[Term] +id: GO:0002321 +name: natural killer cell progenitor differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor." [GOC:add, PMID:16551251, PMID:16551264] +is_a: GO:0002320 ! lymphoid progenitor cell differentiation + +[Term] +id: GO:0002322 +name: B cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of a B cell population by cell division following B cell activation during an immune response." [GOC:jal] +synonym: "B cell proliferation during immune response" RELATED [GOC:tb] +synonym: "B lymphocyte proliferation during immune response" RELATED [] +synonym: "B-cell proliferation during immune response" RELATED [] +synonym: "B-lymphocyte proliferation during immune response" RELATED [] +is_a: GO:0002312 ! B cell activation involved in immune response +is_a: GO:0042100 ! B cell proliferation +intersection_of: GO:0042100 ! B cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002323 +name: natural killer cell activation involved in immune response +namespace: biological_process +def: "The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, PMID:15032583] +synonym: "natural killer cell activation during immune response" RELATED [GOC:tb] +synonym: "NK cell activation during immune response" RELATED [] +is_a: GO:0002285 ! lymphocyte activation involved in immune response +is_a: GO:0030101 ! natural killer cell activation +intersection_of: GO:0030101 ! natural killer cell activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002324 +name: natural killer cell proliferation involved in immune response +namespace: biological_process +def: "The expansion of a natural killer cell population by cell division as part of an immune response." [GOC:add, PMID:15032583] +synonym: "natural killer cell proliferation during immune response" RELATED [GOC:tb] +synonym: "NK cell proliferation during immune response" RELATED [] +is_a: GO:0001787 ! natural killer cell proliferation +is_a: GO:0002323 ! natural killer cell activation involved in immune response +intersection_of: GO:0001787 ! natural killer cell proliferation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002325 +name: natural killer cell differentiation involved in immune response +namespace: biological_process +def: "The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response." [GOC:add, PMID:11698225] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "natural killer cell development involved in immune response" RELATED [GOC:add] +synonym: "natural killer cell differentiation during immune response" RELATED [GOC:tb] +synonym: "NK cell differentiation during immune response" RELATED [] +is_a: GO:0001779 ! natural killer cell differentiation +is_a: GO:0002323 ! natural killer cell activation involved in immune response +intersection_of: GO:0001779 ! natural killer cell differentiation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002326 +name: B cell lineage commitment +namespace: biological_process +def: "The process in which a lymphoid progenitor cell becomes committed to become any type of B cell." [GOC:add, ISBN:0781735149] +synonym: "B lymphocyte lineage commitment" EXACT [] +synonym: "B-cell lineage commitment" EXACT [] +synonym: "B-lymphocyte lineage commitment" EXACT [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0030183 ! B cell differentiation + +[Term] +id: GO:0002327 +name: immature B cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of an immature B cell." [GOC:jal, ISBN:0781735149, PMID:16551251] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "immature B cell development" RELATED [GOC:add] +synonym: "immature B lymphocyte differentiation" EXACT [] +synonym: "immature B-cell differentiation" EXACT [] +synonym: "immature B-lymphocyte differentiation" EXACT [] +is_a: GO:0030183 ! B cell differentiation + +[Term] +id: GO:0002328 +name: pro-B cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed." [GOC:jal, ISBN:0781735149] +synonym: "pro-B cell development" RELATED [GOC:add] +synonym: "pro-B lymphocyte differentiation" EXACT [] +is_a: GO:0002320 ! lymphoid progenitor cell differentiation + +[Term] +id: GO:0002329 +name: pre-B cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "pre-B cell development" RELATED [GOC:add] +synonym: "pre-B lymphocyte differentiation" EXACT [] +is_a: GO:0002327 ! immature B cell differentiation + +[Term] +id: GO:0002330 +name: pre-B cell receptor expression +namespace: biological_process +def: "The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface." [GOC:add, GOC:jal, ISBN:0781735149] +is_a: GO:0010467 ! gene expression +relationship: part_of GO:0002329 ! pre-B cell differentiation + +[Term] +id: GO:0002331 +name: pre-B cell allelic exclusion +namespace: biological_process +def: "Expression of a single heavy chain allele during pre-B cell differentiation." [GOC:add, GOC:jal, ISBN:0781735149] +synonym: "pre-B lymphocyte allelic exclusion" EXACT [] +is_a: GO:0010468 ! regulation of gene expression +relationship: part_of GO:0002329 ! pre-B cell differentiation + +[Term] +id: GO:0002332 +name: transitional stage B cell differentiation +namespace: biological_process +def: "The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "transitional stage B cell development" RELATED [GOC:add] +synonym: "transitional stage B lymphocyte differentiation" EXACT [] +synonym: "transitional stage B-cell differentiation" EXACT [] +synonym: "transitional stage B-lymphocyte differentiation" EXACT [] +is_a: GO:0002327 ! immature B cell differentiation + +[Term] +id: GO:0002333 +name: transitional one stage B cell differentiation +namespace: biological_process +def: "The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T1 stage B cell differentiation" EXACT [] +synonym: "transitional one stage B cell development" RELATED [GOC:add] +synonym: "transitional one stage B lymphocyte differentiation" EXACT [] +synonym: "transitional one stage B-cell differentiation" EXACT [] +synonym: "transitional one stage B-lymphocyte differentiation" EXACT [] +is_a: GO:0002332 ! transitional stage B cell differentiation + +[Term] +id: GO:0002334 +name: transitional two stage B cell differentiation +namespace: biological_process +def: "The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T2 stage B cell differentiation" EXACT [] +synonym: "transitional two stage B cell development" RELATED [GOC:add] +synonym: "transitional two stage B lymphocyte differentiation" EXACT [] +synonym: "transitional two stage B-cell differentiation" EXACT [] +synonym: "transitional two stage B-lymphocyte differentiation" EXACT [] +is_a: GO:0002332 ! transitional stage B cell differentiation + +[Term] +id: GO:0002335 +name: mature B cell differentiation +namespace: biological_process +def: "The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "mature B lymphocyte differentiation" EXACT [] +synonym: "mature B-cell differentiation" EXACT [] +synonym: "mature B-lymphocyte differentiation" EXACT [] +synonym: "mature cell development" RELATED [GOC:add] +is_a: GO:0030183 ! B cell differentiation + +[Term] +id: GO:0002336 +name: B-1 B cell lineage commitment +namespace: biological_process +def: "The process in which an immature B cell becomes committed to become a B-1 B cell." [GOC:jal, ISBN:0781735149] +synonym: "B-1 B lymphocyte lineage commitment" EXACT [] +synonym: "B-1 B-cell lineage commitment" EXACT [] +synonym: "B-1 B-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002326 ! B cell lineage commitment +relationship: part_of GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0002337 +name: B-1a B cell differentiation +namespace: biological_process +def: "The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "B-1a B cell development" RELATED [GOC:add] +synonym: "B-1a B lymphocyte differentiation" EXACT [] +synonym: "B-1a B-cell differentiation" EXACT [] +synonym: "B-1a B-lymphocyte differentiation" EXACT [] +is_a: GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0002338 +name: B-1b B cell differentiation +namespace: biological_process +def: "The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5." [GOC:jal, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "B-1b B cell development" RELATED [GOC:add] +synonym: "B-1b B lymphocyte differentiation" EXACT [] +synonym: "B-1b B-cell differentiation" EXACT [] +synonym: "B-1b B-lymphocyte differentiation" EXACT [] +is_a: GO:0001923 ! B-1 B cell differentiation + +[Term] +id: GO:0002339 +name: B cell selection +namespace: biological_process +def: "The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival." [GOC:jal] +synonym: "B lymphocyte selection" EXACT [] +synonym: "B-cell selection" EXACT [] +synonym: "B-lymphocyte selection" EXACT [] +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0030183 ! B cell differentiation + +[Term] +id: GO:0002340 +name: central B cell selection +namespace: biological_process +def: "Any B cell selection process that occurs in the bone marrow." [GOC:jal] +synonym: "central B lymphocyte selection" EXACT [] +synonym: "central B-cell selection" EXACT [] +synonym: "central B-lymphocyte selection" EXACT [] +is_a: GO:0002339 ! B cell selection + +[Term] +id: GO:0002341 +name: central B cell anergy +namespace: biological_process +def: "Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow." [GOC:jal] +synonym: "central B lymphocyte anergy" EXACT [] +synonym: "central B-cell anergy" EXACT [] +synonym: "central B-lymphocyte anergy" EXACT [] +is_a: GO:0002515 ! B cell anergy +relationship: part_of GO:0002340 ! central B cell selection +relationship: part_of GO:0002510 ! central B cell tolerance induction + +[Term] +id: GO:0002342 +name: central B cell deletion +namespace: biological_process +def: "The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection." [GOC:add, GOC:jal, GOC:mtg_apoptosis] +synonym: "central B lymphocyte deletion" EXACT [] +synonym: "central B-cell deletion" EXACT [] +synonym: "central B-lymphocyte deletion" EXACT [] +is_a: GO:0002516 ! B cell deletion +relationship: part_of GO:0002340 ! central B cell selection +relationship: part_of GO:0002510 ! central B cell tolerance induction + +[Term] +id: GO:0002343 +name: peripheral B cell selection +namespace: biological_process +def: "Any B cell selection process that occurs in the periphery." [GOC:jal] +synonym: "peripheral B lymphocyte selection" EXACT [] +synonym: "peripheral B-cell selection" EXACT [] +synonym: "peripheral B-lymphocyte selection" EXACT [] +is_a: GO:0002339 ! B cell selection + +[Term] +id: GO:0002344 +name: B cell affinity maturation +namespace: biological_process +def: "The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +synonym: "B lymphocyte affinity maturation" EXACT [] +synonym: "B-cell affinity maturation" EXACT [] +synonym: "B-lymphocyte affinity maturation" EXACT [] +is_a: GO:0002343 ! peripheral B cell selection +relationship: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response + +[Term] +id: GO:0002345 +name: peripheral B cell receptor editing +namespace: biological_process +def: "The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation." [GOC:jal] +synonym: "peripheral B lymphocyte receptor editing" EXACT [] +synonym: "peripheral B-cell receptor editing" EXACT [] +synonym: "peripheral B-lymphocyte receptor editing" EXACT [] +is_a: GO:0002452 ! B cell receptor editing + +[Term] +id: GO:0002346 +name: B cell positive selection +namespace: biological_process +def: "Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor." [GOC:jal] +synonym: "B lymphocyte positive selection" EXACT [] +synonym: "B-cell positive selection" EXACT [] +synonym: "B-lymphocyte positive selection" EXACT [] +is_a: GO:0002339 ! B cell selection + +[Term] +id: GO:0002347 +name: response to tumor cell +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0009607 ! response to biotic stimulus + +[Term] +id: GO:0002348 +name: central B cell positive selection +namespace: biological_process +def: "Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors." [GOC:jal] +synonym: "central B lymphocyte positive selection" EXACT [] +synonym: "central B-cell positive selection" EXACT [] +synonym: "central B-lymphocyte positive selection" EXACT [] +is_a: GO:0002340 ! central B cell selection +is_a: GO:0002346 ! B cell positive selection + +[Term] +id: GO:0002349 +name: histamine production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] +synonym: "histamine production involved in acute inflammatory response" BROAD [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response + +[Term] +id: GO:0002350 +name: peripheral B cell positive selection +namespace: biological_process +def: "Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors." [GOC:jal] +synonym: "peripheral B lymphocyte positive selection" EXACT [] +synonym: "peripheral B-cell positive selection" EXACT [] +synonym: "peripheral B-lymphocyte positive selection" EXACT [] +is_a: GO:0002343 ! peripheral B cell selection +is_a: GO:0002346 ! B cell positive selection + +[Term] +id: GO:0002351 +name: serotonin production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] +synonym: "serotonin production involved in acute inflammatory response" BROAD [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response + +[Term] +id: GO:0002352 +name: B cell negative selection +namespace: biological_process +def: "Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion." [GOC:jal] +synonym: "B lymphocyte negative selection" EXACT [] +synonym: "B-cell negative selection" EXACT [] +synonym: "B-lymphocyte negative selection" EXACT [] +is_a: GO:0002339 ! B cell selection + +[Term] +id: GO:0002353 +name: plasma kallikrein-kinin cascade +namespace: biological_process +def: "A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability." [GOC:add, ISBN:0721601871, PMID:11842287, PMID:14501145] +is_a: GO:0002254 ! kinin cascade + +[Term] +id: GO:0002354 +name: central B cell negative selection +namespace: biological_process +def: "Any process leading to negative selection of B cells in the bone marrow." [GOC:jal] +synonym: "central B lymphocyte negative selection" EXACT [] +synonym: "central B-cell negative selection" EXACT [] +synonym: "central B-lymphocyte negative selection" EXACT [] +is_a: GO:0002340 ! central B cell selection +is_a: GO:0002352 ! B cell negative selection + +[Term] +id: GO:0002355 +name: detection of tumor cell +namespace: biological_process +def: "The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0002347 ! response to tumor cell +is_a: GO:0009595 ! detection of biotic stimulus + +[Term] +id: GO:0002356 +name: peripheral B cell negative selection +namespace: biological_process +def: "Any process leading to negative selection of B cells in the periphery." [GOC:jal] +synonym: "peripheral B lymphocyte negative selection" EXACT [] +synonym: "peripheral B-cell negative selection" EXACT [] +synonym: "peripheral B-lymphocyte negative selection" EXACT [] +is_a: GO:0002343 ! peripheral B cell selection +is_a: GO:0002352 ! B cell negative selection + +[Term] +id: GO:0002357 +name: defense response to tumor cell +namespace: biological_process +def: "Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0002347 ! response to tumor cell +is_a: GO:0006952 ! defense response + +[Term] +id: GO:0002358 +name: B cell homeostatic proliferation +namespace: biological_process +def: "The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus." [GOC:jal] +synonym: "B lymphocyte homeostatic proliferation" EXACT [] +synonym: "B-cell homeostatic proliferation" EXACT [] +synonym: "B-lymphocyte homeostatic proliferation" EXACT [] +is_a: GO:0042100 ! B cell proliferation +relationship: part_of GO:0042592 ! homeostatic process + +[Term] +id: GO:0002359 +name: B-1 B cell proliferation +namespace: biological_process +def: "The expansion of a B-1 B cell by cell division. Follows B cell activation." [GOC:jal] +synonym: "B-1 B lymphocyte proliferation" EXACT [] +synonym: "B-1 B-cell proliferation" EXACT [] +synonym: "B-1 B-lymphocyte proliferation" EXACT [] +is_a: GO:0042100 ! B cell proliferation + +[Term] +id: GO:0002360 +name: T cell lineage commitment +namespace: biological_process +def: "The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell." [GOC:add, ISBN:0781735149] +synonym: "T lymphocyte lineage commitment" EXACT [] +synonym: "T-cell lineage commitment" EXACT [] +synonym: "T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0030217 ! T cell differentiation + +[Term] +id: GO:0002361 +name: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell." [GOC:add, PMID:15207821] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T cell development" RELATED [GOC:add] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] +is_a: GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045066 ! regulatory T cell differentiation + +[Term] +id: GO:0002362 +name: CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment +namespace: biological_process +def: "The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell." [GOC:add, PMID:15207821] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte lineage commitment" EXACT [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-cell lineage commitment" EXACT [] +synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0043373 ! CD4-positive, alpha-beta T cell lineage commitment +relationship: part_of GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + +[Term] +id: GO:0002363 +name: alpha-beta T cell lineage commitment +namespace: biological_process +def: "The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell." [GOC:add, ISBN:0781735149] +synonym: "alpha-beta T lymphocyte lineage commitment" EXACT [] +synonym: "alpha-beta T-cell lineage commitment" EXACT [] +synonym: "alpha-beta T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002360 ! T cell lineage commitment +relationship: part_of GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0002364 +name: NK T cell lineage commitment +namespace: biological_process +def: "The process in which a pro-T cell becomes committed to becoming an NK T cell." [GOC:add, ISBN:0781735149] +synonym: "natural killer T lymphocyte lineage commitment" EXACT [] +synonym: "natural killer T-cell lineage commitment" EXACT [] +synonym: "natural killer T-lymphocyte lineage commitment" EXACT [] +synonym: "NK T lymphocyte lineage commitment" EXACT [] +synonym: "NK T-cell lineage commitment" EXACT [] +synonym: "NK T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002363 ! alpha-beta T cell lineage commitment +relationship: part_of GO:0001865 ! NK T cell differentiation + +[Term] +id: GO:0002365 +name: gamma-delta T cell lineage commitment +namespace: biological_process +def: "The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell." [GOC:add, ISBN:0781735149] +synonym: "gamma-delta T lymphocyte lineage commitment" EXACT [] +synonym: "gamma-delta T-cell lineage commitment" EXACT [] +synonym: "gamma-delta T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002360 ! T cell lineage commitment +relationship: part_of GO:0042492 ! gamma-delta T cell differentiation + +[Term] +id: GO:0002366 +name: leukocyte activation involved in immune response +namespace: biological_process +def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] +synonym: "immune cell activation during immune response" RELATED [] +synonym: "leucocyte activation during immune response" RELATED [] +synonym: "leukocyte activation during immune response" RELATED [GOC:tb] +is_a: GO:0002263 ! cell activation involved in immune response +is_a: GO:0045321 ! leukocyte activation +intersection_of: GO:0045321 ! leukocyte activation +intersection_of: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002367 +name: cytokine production involved in immune response +namespace: biological_process +def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] +comment: Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular cytokine levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting cytokine molecules, or increased conversion from precursor molecules. +synonym: "cytokine production during immune response" RELATED [GOC:dph] +is_a: GO:0001816 ! cytokine production +is_a: GO:0002440 ! production of molecular mediator of immune response +intersection_of: GO:0001816 ! cytokine production +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002368 +name: B cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a B cell." [GOC:add, ISBN:0781735149] +synonym: "B lymphocyte cytokine production" EXACT [] +synonym: "B-cell cytokine production" EXACT [] +synonym: "B-lymphocyte cytokine production" EXACT [] +is_a: GO:0002367 ! cytokine production involved in immune response +is_a: GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002369 +name: T cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149] +synonym: "T lymphocyte cytokine production" EXACT [] +synonym: "T-cell cytokine production" EXACT [] +synonym: "T-lymphocyte cytokine production" EXACT [] +is_a: GO:0002367 ! cytokine production involved in immune response +is_a: GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002370 +name: natural killer cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a natural killer cell." [GOC:add, ISBN:0781735149] +synonym: "NK cell cytokine production" EXACT [] +is_a: GO:0002228 ! natural killer cell mediated immunity +is_a: GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002371 +name: dendritic cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149] +is_a: GO:0002367 ! cytokine production involved in immune response +is_a: GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002372 +name: myeloid dendritic cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a myeloid dendritic cell." [GOC:add, ISBN:0781735149] +is_a: GO:0002371 ! dendritic cell cytokine production +is_a: GO:0002444 ! myeloid leukocyte mediated immunity +is_a: GO:0061082 ! myeloid leukocyte cytokine production + +[Term] +id: GO:0002373 +name: plasmacytoid dendritic cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a plasmacytoid dendritic cell." [GOC:add, ISBN:0781735149] +is_a: GO:0002371 ! dendritic cell cytokine production + +[Term] +id: GO:0002374 +name: cytokine secretion involved in immune response +namespace: biological_process +def: "The regulated release of cytokines from a cell that contributes to an immune response." [GOC:add, ISBN:0781735149] +synonym: "cytokine secretion during immune response" RELATED [GOC:dph] +is_a: GO:0050663 ! cytokine secretion +intersection_of: GO:0050663 ! cytokine secretion +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002375 +name: cytokine biosynthetic process involved in immune response +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cytokine that contributes to an immune response." [GOC:add, ISBN:0781735149] +synonym: "cytokine biosynthetic process during immune response" RELATED [GOC:dph] +is_a: GO:0042089 ! cytokine biosynthetic process +intersection_of: GO:0042089 ! cytokine biosynthetic process +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002376 +name: immune system process +namespace: biological_process +def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add] +comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +xref: Wikipedia:Immune_system +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0002377 +name: immunoglobulin production +namespace: biological_process +def: "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "antibody production" EXACT [] +is_a: GO:0002440 ! production of molecular mediator of immune response + +[Term] +id: GO:0002378 +name: immunoglobulin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of immunoglobulin." [GOC:add, ISBN:0781735149] +synonym: "antibody biosynthesis" EXACT [] +synonym: "antibody biosynthetic process" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +relationship: part_of GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0002379 +name: immunoglobulin biosynthetic process involved in immune response +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of immunoglobulin contributing to an immune response." [GOC:add, ISBN:0781735149] +synonym: "antibody biosynthesis during immune response" RELATED [] +synonym: "antibody biosynthetic process during immune response" RELATED [] +synonym: "immunoglobulin biosynthetic process during immune response" RELATED [GOC:dph] +is_a: GO:0002378 ! immunoglobulin biosynthetic process +intersection_of: GO:0002378 ! immunoglobulin biosynthetic process +intersection_of: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response +relationship: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response + +[Term] +id: GO:0002380 +name: immunoglobulin secretion involved in immune response +namespace: biological_process +def: "The regulated release of immunoglobulins from a B cell or plasma cell contributing to an immune response." [GOC:add, ISBN:0781735149, PMID:9185563] +synonym: "antibody secretion during immune response" RELATED [] +synonym: "immunoglobulin secretion during immune response" RELATED [goc:dph] +is_a: GO:0048305 ! immunoglobulin secretion +intersection_of: GO:0048305 ! immunoglobulin secretion +intersection_of: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response +relationship: part_of GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response + +[Term] +id: GO:0002381 +name: immunoglobulin production involved in immunoglobulin mediated immune response +namespace: biological_process +def: "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "antibody production during immune response" RELATED [] +synonym: "immunoglobulin production during immune response" RELATED [GOC:dph] +synonym: "immunoglobulin production involved in immune response" RELATED [GOC:dph] +is_a: GO:0002377 ! immunoglobulin production +intersection_of: GO:0002377 ! immunoglobulin production +intersection_of: part_of GO:0016064 ! immunoglobulin mediated immune response +relationship: part_of GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002382 +name: regulation of tissue kallikrein-kinin cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade." [GOC:add] +synonym: "regulation of glandular kallikrein-kinin cascade" EXACT [] +is_a: GO:0002256 ! regulation of kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002255 ! tissue kallikrein-kinin cascade +relationship: regulates GO:0002255 ! tissue kallikrein-kinin cascade + +[Term] +id: GO:0002383 +name: immune response in brain or nervous system +namespace: biological_process +def: "An immune response taking place in the brain or nervous system." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002251 ! organ or tissue specific immune response + +[Term] +id: GO:0002384 +name: hepatic immune response +namespace: biological_process +def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002251 ! organ or tissue specific immune response + +[Term] +id: GO:0002385 +name: mucosal immune response +namespace: biological_process +def: "An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002251 ! organ or tissue specific immune response + +[Term] +id: GO:0002386 +name: immune response in mucosal-associated lymphoid tissue +namespace: biological_process +def: "Immune response taking place in the mucosal-associated lymphoid tissue (MALT). Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes." [GOC:jal, ISBN:0781735149] +synonym: "immune response in MALT" EXACT [] +is_a: GO:0002385 ! mucosal immune response + +[Term] +id: GO:0002387 +name: immune response in gut-associated lymphoid tissue +namespace: biological_process +def: "Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules." [GOC:jal, ISBN:0781735149] +synonym: "immune response in GALT" EXACT [] +is_a: GO:0002386 ! immune response in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002388 +name: immune response in Peyer's patch +namespace: biological_process +def: "Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine." [GOC:jal, ISBN:0781735149] +is_a: GO:0002387 ! immune response in gut-associated lymphoid tissue + +[Term] +id: GO:0002389 +name: tolerance induction in Peyer's patch +namespace: biological_process +def: "Tolerance induction taking place in the Peyer's patches." [GOC:jal, ISBN:0781735149] +is_a: GO:0002388 ! immune response in Peyer's patch +is_a: GO:0002394 ! tolerance induction in gut-associated lymphoid tissue + +[Term] +id: GO:0002390 +name: platelet activating factor production +namespace: biological_process +def: "The synthesis or release of platelet activating factor following a stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0002391 +name: platelet activating factor production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "platelet activating factor production involved in acute inflammatory response" BROAD [] +is_a: GO:0002390 ! platelet activating factor production +is_a: GO:0002534 ! cytokine production involved in inflammatory response +intersection_of: GO:0002390 ! platelet activating factor production +intersection_of: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002392 +name: platelet activating factor secretion +namespace: biological_process +def: "The regulated release of platelet activating factor by a cell." [GOC:add, ISBN:0781735149] +is_a: GO:0010876 ! lipid localization +is_a: GO:0015697 ! quaternary ammonium group transport +is_a: GO:0015893 ! drug transport +is_a: GO:0015914 ! phospholipid transport +is_a: GO:0050663 ! cytokine secretion +is_a: GO:0140353 ! lipid export from cell + +[Term] +id: GO:0002393 +name: lysosomal enzyme production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels." [GOC:add] +synonym: "lysosomal enzyme production involved in acute inflammatory response" BROAD [GOC:mah] +synonym: "production of lysosomal enzymes involved in acute inflammatory response" BROAD [] +synonym: "production of lysosomal enzymes involved in inflammatory response" EXACT [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response + +[Term] +id: GO:0002394 +name: tolerance induction in gut-associated lymphoid tissue +namespace: biological_process +def: "Tolerance induction taking place in the gut-associated lymphoid tissue (GALT)." [GOC:jal, ISBN:0781735149] +synonym: "oral tolerance" RELATED [] +synonym: "tolerance induction in GALT" EXACT [] +is_a: GO:0002387 ! immune response in gut-associated lymphoid tissue +is_a: GO:0002401 ! tolerance induction in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002395 +name: immune response in nasopharyngeal-associated lymphoid tissue +namespace: biological_process +def: "An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids." [GOC:jal, ISBN:0781735149] +synonym: "immune response in NALT" EXACT [] +is_a: GO:0002387 ! immune response in gut-associated lymphoid tissue + +[Term] +id: GO:0002396 +name: MHC protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0002397 +name: MHC class I protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002396 ! MHC protein complex assembly + +[Term] +id: GO:0002398 +name: MHC class Ib protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules." [GOC:add, PMID:15928678, PMID:15928680] +is_a: GO:0002396 ! MHC protein complex assembly + +[Term] +id: GO:0002399 +name: MHC class II protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002396 ! MHC protein complex assembly + +[Term] +id: GO:0002400 +name: tolerance induction in nasopharyngeal-associated lymphoid tissue +namespace: biological_process +def: "Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT)." [GOC:jal, ISBN:0781735149] +synonym: "nasal tolerance" RELATED [] +synonym: "tolerance induction in NALT" EXACT [] +is_a: GO:0002394 ! tolerance induction in gut-associated lymphoid tissue +is_a: GO:0002395 ! immune response in nasopharyngeal-associated lymphoid tissue + +[Term] +id: GO:0002401 +name: tolerance induction in mucosal-associated lymphoid tissue +namespace: biological_process +def: "Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT)." [GOC:jal, ISBN:0781735149] +synonym: "tolerance induction in MALT" EXACT [] +is_a: GO:0002386 ! immune response in mucosal-associated lymphoid tissue +is_a: GO:0002427 ! mucosal tolerance induction + +[Term] +id: GO:0002402 +name: B cell tolerance induction in mucosal-associated lymphoid tissue +namespace: biological_process +def: "Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells." [GOC:jal, ISBN:0781735149] +synonym: "B cell tolerance induction in MALT" EXACT [] +is_a: GO:0002401 ! tolerance induction in mucosal-associated lymphoid tissue +is_a: GO:0002451 ! peripheral B cell tolerance induction + +[Term] +id: GO:0002403 +name: T cell tolerance induction in mucosal-associated lymphoid tissue +namespace: biological_process +def: "Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells." [GOC:jal, ISBN:0781735149, PMID:16551263] +synonym: "T cell tolerance induction in MALT" EXACT [] +is_a: GO:0002401 ! tolerance induction in mucosal-associated lymphoid tissue +is_a: GO:0002458 ! peripheral T cell tolerance induction + +[Term] +id: GO:0002404 +name: antigen sampling in mucosal-associated lymphoid tissue +namespace: biological_process +def: "The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue." [GOC:jal, PMID:11896763, PMID:12843411, PMID:15681746] +synonym: "antigen sampling in MALT" EXACT [] +synonym: "antigen transport in MALT" RELATED [] +synonym: "antigen transport in mucosal-associated lymphoid tissue" RELATED [] +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0002386 ! immune response in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002405 +name: antigen sampling by dendritic cells in mucosal-associated lymphoid tissue +namespace: biological_process +def: "The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue." [GOC:jal, PMID:11896763, PMID:15681746] +synonym: "antigen sampling by dendritic cells in MALT" EXACT [] +is_a: GO:0002404 ! antigen sampling in mucosal-associated lymphoid tissue +relationship: part_of GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002406 +name: antigen sampling by M cells in mucosal-associated lymphoid tissue +namespace: biological_process +def: "The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue." [GOC:jal, PMID:11896763] +synonym: "antigen sampling by M cells in MALT" EXACT [] +is_a: GO:0002404 ! antigen sampling in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002407 +name: dendritic cell chemotaxis +namespace: biological_process +def: "The movement of a dendritic cell in response to an external stimulus." [CL:0000451, GOC:add, ISBN:0781735149, PMID:15814331, PMID:16056255] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:0036336 ! dendritic cell migration + +[Term] +id: GO:0002408 +name: myeloid dendritic cell chemotaxis +namespace: biological_process +def: "The movement of a myeloid dendritic cell in response to an external stimulus." [GOC:add, ISBN:0781735149, PMID:15814331, PMID:16056255] +is_a: GO:0002407 ! dendritic cell chemotaxis +is_a: GO:0097529 ! myeloid leukocyte migration + +[Term] +id: GO:0002409 +name: Langerhans cell chemotaxis +namespace: biological_process +def: "The movement of a Langerhans cell in response to an external stimulus." [GOC:add, PMID:16056255, PMID:16387601] +is_a: GO:0002408 ! myeloid dendritic cell chemotaxis + +[Term] +id: GO:0002410 +name: plasmacytoid dendritic cell chemotaxis +namespace: biological_process +def: "The movement of a plasmacytoid dendritic cell in response to an external stimulus." [GOC:add, PMID:15159375, PMID:15814331] +is_a: GO:0002407 ! dendritic cell chemotaxis + +[Term] +id: GO:0002411 +name: T cell tolerance induction to tumor cell +namespace: biological_process +def: "A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0002413 ! tolerance induction to tumor cell +is_a: GO:0002424 ! T cell mediated immune response to tumor cell +is_a: GO:0002458 ! peripheral T cell tolerance induction + +[Term] +id: GO:0002412 +name: antigen transcytosis by M cells in mucosal-associated lymphoid tissue +namespace: biological_process +def: "The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT." [GOC:jal, ISBN:0781735149, PMID:12843411] +synonym: "antigen transcytosis by M cells in MALT" EXACT [] +synonym: "antigen transport by M cells in MALT" EXACT [] +synonym: "antigen transport by M cells in mucosal-associated lymphoid tissue" EXACT [] +is_a: GO:0045056 ! transcytosis +relationship: part_of GO:0002406 ! antigen sampling by M cells in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002413 +name: tolerance induction to tumor cell +namespace: biological_process +def: "A process of tolerance induction which leads to immunological tolerance of a tumor." [GOC:add] +is_a: GO:0002418 ! immune response to tumor cell +is_a: GO:0002465 ! peripheral tolerance induction + +[Term] +id: GO:0002414 +name: immunoglobulin transcytosis in epithelial cells +namespace: biological_process +def: "The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other." [GOC:add, ISBN:0781735149, ISBN:081533642X, PMID:16048543] +is_a: GO:0045056 ! transcytosis + +[Term] +id: GO:0002415 +name: immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor +namespace: biological_process +def: "The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa." [GOC:add, ISBN:0781735149, ISBN:081533642X, PMID:16048543] +synonym: "antibody transcytosis mediated by pIgR" EXACT [] +synonym: "immunoglobulin transcytosis mediated by pIgR" EXACT [] +is_a: GO:0002414 ! immunoglobulin transcytosis in epithelial cells +relationship: part_of GO:0002386 ! immune response in mucosal-associated lymphoid tissue + +[Term] +id: GO:0002416 +name: IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor +namespace: biological_process +def: "The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals." [GOC:add, ISBN:0781735149, ISBN:081533642X] +synonym: "IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor" EXACT [] +synonym: "IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor" EXACT [] +is_a: GO:0002414 ! immunoglobulin transcytosis in epithelial cells + +[Term] +id: GO:0002417 +name: B cell antigen processing and presentation mediated by B cell receptor uptake of antigen +namespace: biological_process +def: "B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen" EXACT [] +synonym: "B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen" EXACT [] +synonym: "B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen" EXACT [] +is_a: GO:0002450 ! B cell antigen processing and presentation +is_a: GO:0002751 ! antigen processing and presentation following receptor mediated endocytosis + +[Term] +id: GO:0002418 +name: immune response to tumor cell +namespace: biological_process +def: "An immune system process that functions in the response of an organism to a tumor cell." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0002347 ! response to tumor cell +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0002419 +name: T cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, ISBN:0781735149, PMID:16730260] +comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. +synonym: "T lymphocyte mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "T-cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "T-lymphocyte mediated cytotoxicity directed against tumor cell target" EXACT [] +is_a: GO:0001913 ! T cell mediated cytotoxicity +is_a: GO:0002424 ! T cell mediated immune response to tumor cell + +[Term] +id: GO:0002420 +name: natural killer cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, ISBN:0781735149, PMID:16730260] +comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. +synonym: "NK cell mediated cytotoxicity directed against tumor cell target" EXACT [] +is_a: GO:0002423 ! natural killer cell mediated immune response to tumor cell +is_a: GO:0042267 ! natural killer cell mediated cytotoxicity + +[Term] +id: GO:0002421 +name: B cell antigen processing and presentation following pinocytosis +namespace: biological_process +def: "B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis." [GOC:add, PMID:7543530] +synonym: "B lymphocyte antigen processing and presentation following pinocytosis" EXACT [] +synonym: "B-cell antigen processing and presentation following pinocytosis" EXACT [] +synonym: "B-lymphocyte antigen processing and presentation following pinocytosis" EXACT [] +is_a: GO:0002450 ! B cell antigen processing and presentation +is_a: GO:0002746 ! antigen processing and presentation following pinocytosis + +[Term] +id: GO:0002422 +name: immune response in urogenital tract +namespace: biological_process +def: "An immune response taking place in the urogenital tract. The urogenital tract." [GOC:jal] +is_a: GO:0002385 ! mucosal immune response + +[Term] +id: GO:0002423 +name: natural killer cell mediated immune response to tumor cell +namespace: biological_process +def: "An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell." [GOC:add, ISBN:0781735149, PMID:16730260] +is_a: GO:0002228 ! natural killer cell mediated immunity +is_a: GO:0002418 ! immune response to tumor cell + +[Term] +id: GO:0002424 +name: T cell mediated immune response to tumor cell +namespace: biological_process +def: "An immune response mediated by a T cell triggered in response to the presence of a tumor cell." [GOC:add, ISBN:0781735149, PMID:16730260] +comment: Note that this term includes tolerogenic responses to tumor cells mediated by responding T cells. +is_a: GO:0002418 ! immune response to tumor cell +is_a: GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002425 +name: tolerance induction in urogenital tract +namespace: biological_process +def: "Tolerance induction taking place in the urogenital tract." [GOC:jal] +is_a: GO:0002422 ! immune response in urogenital tract +is_a: GO:0002427 ! mucosal tolerance induction + +[Term] +id: GO:0002426 +name: immunoglobulin production in mucosal tissue +namespace: biological_process +def: "The synthesis and release of immunoglobulin in the mucosal tissue." [GOC:jal] +synonym: "antibody production in mucosal tissue" EXACT [] +is_a: GO:0002381 ! immunoglobulin production involved in immunoglobulin mediated immune response +relationship: part_of GO:0002385 ! mucosal immune response + +[Term] +id: GO:0002427 +name: mucosal tolerance induction +namespace: biological_process +def: "Tolerance induction taking place in the mucosal tissues." [GOC:jal] +is_a: GO:0002385 ! mucosal immune response +is_a: GO:0002462 ! tolerance induction to nonself antigen + +[Term] +id: GO:0002428 +name: antigen processing and presentation of peptide antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family." [GOC:add, PMID:15928678] +synonym: "peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002475 ! antigen processing and presentation via MHC class Ib +is_a: GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002429 +name: immune response-activating cell surface receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "activation of immune response by cell surface receptor signaling pathway" EXACT [] +synonym: "immune response-activating cell surface receptor signalling pathway" EXACT [] +is_a: GO:0002757 ! immune response-activating signal transduction +is_a: GO:0002768 ! immune response-regulating cell surface receptor signaling pathway + +[Term] +id: GO:0002430 +name: complement receptor mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "complement receptor mediated signalling pathway" EXACT [] +synonym: "immune response-regulating cell surface receptor signalling pathway" BROAD [] +is_a: GO:0002429 ! immune response-activating cell surface receptor signaling pathway + +[Term] +id: GO:0002431 +name: Fc receptor mediated stimulatory signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "Fc receptor mediated stimulatory signalling pathway" EXACT [] +synonym: "Fc-receptor mediated stimulatory signaling pathway" EXACT [] +is_a: GO:0002429 ! immune response-activating cell surface receptor signaling pathway + +[Term] +id: GO:0002432 +name: granuloma formation +namespace: biological_process +def: "The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic." [GO_REF:0000022, GOC:add, ISBN:068340007X, ISBN:0721601464, ISBN:081533642X] +is_a: GO:0002252 ! immune effector process +relationship: part_of GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002433 +name: immune response-regulating cell surface receptor signaling pathway involved in phagocytosis +namespace: biological_process +def: "An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes." [GO_REF:0000022, GOC:add, GOC:bf, ISBN:0781735149] +synonym: "immune response-regulating cell surface receptor signalling pathway involved in phagocytosis" EXACT [GOC:mah] +synonym: "phagocytosis triggered by activation of immune response cell surface activating receptor" EXACT [] +is_a: GO:0002252 ! immune effector process +is_a: GO:0002768 ! immune response-regulating cell surface receptor signaling pathway +intersection_of: GO:0002768 ! immune response-regulating cell surface receptor signaling pathway +intersection_of: part_of GO:0006909 ! phagocytosis +relationship: part_of GO:0006909 ! phagocytosis + +[Term] +id: GO:0002434 +name: immune complex clearance +namespace: biological_process +def: "A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution." [GO_REF:0000022, GOC:add, ISBN:068340007X] +is_a: GO:0002252 ! immune effector process + +[Term] +id: GO:0002435 +name: immune complex clearance by erythrocytes +namespace: biological_process +def: "The process of immune complex clearance by erythrocytes." [GOC:add, PMID:11414352] +synonym: "immune complex clearance by RBCs" EXACT [CL:0000232] +synonym: "immune complex clearance by red blood cells" EXACT [CL:0000232] +is_a: GO:0002434 ! immune complex clearance + +[Term] +id: GO:0002436 +name: immune complex clearance by monocytes and macrophages +namespace: biological_process +def: "The process of immune complex clearance by monocytes or macrophages." [GOC:add, ISBN:0781735149] +is_a: GO:0002434 ! immune complex clearance + +[Term] +id: GO:0002437 +name: inflammatory response to antigenic stimulus +namespace: biological_process +def: "An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes." [GOC:add, ISBN:0781735149] +is_a: GO:0006954 ! inflammatory response +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0002438 +name: acute inflammatory response to antigenic stimulus +namespace: biological_process +def: "An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002437 ! inflammatory response to antigenic stimulus +is_a: GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002439 +name: chronic inflammatory response to antigenic stimulus +namespace: biological_process +def: "A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual." [GOC:add, ISBN:0781735149] +is_a: GO:0002437 ! inflammatory response to antigenic stimulus +is_a: GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002440 +name: production of molecular mediator of immune response +namespace: biological_process +def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "production of cellular mediator of immune response" RELATED [] +is_a: GO:0002376 ! immune system process + +[Term] +id: GO:0002441 +name: histamine secretion involved in inflammatory response +namespace: biological_process +def: "The regulated release of histamine by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "histamine secretion involved in acute inflammatory response" BROAD [] +is_a: GO:0001821 ! histamine secretion +is_a: GO:0046879 ! hormone secretion +intersection_of: GO:0001821 ! histamine secretion +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0002349 ! histamine production involved in inflammatory response + +[Term] +id: GO:0002442 +name: serotonin secretion involved in inflammatory response +namespace: biological_process +def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "serotonin release involved in inflammatory response" RELATED [GOC:tb] +synonym: "serotonin secretion involved in acute inflammatory response" BROAD [] +is_a: GO:0001820 ! serotonin secretion +intersection_of: GO:0001820 ! serotonin secretion +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0002351 ! serotonin production involved in inflammatory response + +[Term] +id: GO:0002443 +name: leukocyte mediated immunity +namespace: biological_process +alt_id: GO:0019723 +alt_id: GO:0042087 +def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "cell-mediated immune response" RELATED [] +synonym: "cellular immune response" RELATED [] +synonym: "immune cell effector process" EXACT [] +synonym: "immune cell mediated immunity" EXACT [] +synonym: "leucocyte immune effector process" EXACT [] +synonym: "leucocyte mediated immunity" EXACT [] +synonym: "leukocyte immune effector process" EXACT [] +is_a: GO:0002252 ! immune effector process + +[Term] +id: GO:0002444 +name: myeloid leukocyte mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "myeloid leucocyte immune effector process" EXACT [] +synonym: "myeloid leucocyte mediated immunity" EXACT [] +synonym: "myeloid leukocyte immune effector process" EXACT [] +is_a: GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002445 +name: type II hypersensitivity +namespace: biological_process +def: "An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors." [GOC:add, ISBN:0781735149] +xref: Wikipedia:Type_II_hypersensitivity +is_a: GO:0002444 ! myeloid leukocyte mediated immunity +is_a: GO:0002524 ! hypersensitivity +is_a: GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002446 +name: neutrophil mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a neutrophil." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002447 +name: eosinophil mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by an eosinophil." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002448 +name: mast cell mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a mast cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002449 +name: lymphocyte mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "cell-mediated immunity" BROAD [] +synonym: "cellular immune response" BROAD [] +is_a: GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002450 +name: B cell antigen processing and presentation +namespace: biological_process +def: "The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "B lymphocyte antigen processing and presentation" EXACT [] +synonym: "B-cell antigen processing and presentation" EXACT [] +synonym: "B-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation +relationship: part_of GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002451 +name: peripheral B cell tolerance induction +namespace: biological_process +def: "Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue." [GOC:jal, ISBN:0781735149] +synonym: "peripheral B lymphocyte tolerance induction" EXACT [] +synonym: "peripheral B-cell tolerance induction" EXACT [] +synonym: "peripheral B-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002465 ! peripheral tolerance induction +is_a: GO:0002514 ! B cell tolerance induction +is_a: GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002452 +name: B cell receptor editing +namespace: biological_process +def: "The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor." [GOC:jal, ISBN:0781735149] +synonym: "B lymphocyte receptor editing" EXACT [] +synonym: "B-cell receptor editing" EXACT [] +synonym: "B-lymphocyte receptor editing" EXACT [] +is_a: GO:0016447 ! somatic recombination of immunoglobulin gene segments + +[Term] +id: GO:0002453 +name: peripheral B cell anergy +namespace: biological_process +def: "Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells." [GOC:jal, ISBN:0781735149] +synonym: "peripheral B lymphocyte anergy" EXACT [] +synonym: "peripheral B-cell anergy" EXACT [] +synonym: "peripheral B-lymphocyte anergy" EXACT [] +is_a: GO:0002515 ! B cell anergy +relationship: part_of GO:0002451 ! peripheral B cell tolerance induction + +[Term] +id: GO:0002454 +name: peripheral B cell deletion +namespace: biological_process +def: "The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection." [GOC:add, GOC:jal, GOC:mtg_apoptosis, ISBN:0781735149] +synonym: "peripheral B lymphocyte deletion" EXACT [] +synonym: "peripheral B-cell deletion" EXACT [] +synonym: "peripheral B-lymphocyte deletion" EXACT [] +is_a: GO:0002516 ! B cell deletion +relationship: part_of GO:0002451 ! peripheral B cell tolerance induction + +[Term] +id: GO:0002455 +name: humoral immune response mediated by circulating immunoglobulin +namespace: biological_process +def: "An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "circulating antibody mediated immune response" EXACT [] +synonym: "circulating immunoglobulin mediated immune response" EXACT [] +synonym: "humoral defence mechanism" RELATED [] +synonym: "humoral immune response mediated by circulating antibody" EXACT [] +is_a: GO:0006959 ! humoral immune response +is_a: GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002456 +name: T cell mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "cell-mediated immunity" BROAD [] +synonym: "cellular immune response" BROAD [] +synonym: "T lymphocyte mediated immunity" EXACT [] +synonym: "T-cell mediated immunity" EXACT [] +synonym: "T-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002449 ! lymphocyte mediated immunity +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0002457 +name: T cell antigen processing and presentation +namespace: biological_process +def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183] +synonym: "T lymphocyte antigen processing and presentation" EXACT [] +synonym: "T-cell antigen processing and presentation" EXACT [] +synonym: "T-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation +relationship: part_of GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002458 +name: peripheral T cell tolerance induction +namespace: biological_process +def: "Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus." [GOC:jal, ISBN:0781735149] +synonym: "peripheral T lymphocyte tolerance induction" EXACT [] +synonym: "peripheral T-cell tolerance induction" EXACT [] +synonym: "peripheral T-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002456 ! T cell mediated immunity +is_a: GO:0002465 ! peripheral tolerance induction +is_a: GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002459 +name: adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains +namespace: biological_process +def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae)." [GOC:add, GOC:mtg_sensu, PMID:16373579] +synonym: "adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains" EXACT [] +synonym: "adaptive immune response based on somatic recombination of VLR built from LRR domains" EXACT [] +synonym: "adaptive immune response in jawless fish" EXACT [] +is_a: GO:0002250 ! adaptive immune response + +[Term] +id: GO:0002460 +name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +namespace: biological_process +def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831] +is_a: GO:0002250 ! adaptive immune response + +[Term] +id: GO:0002461 +name: tolerance induction dependent upon immune response +namespace: biological_process +def: "Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +synonym: "immune response-dependent tolerance induction" EXACT [] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002462 +name: tolerance induction to nonself antigen +namespace: biological_process +def: "Tolerance induction in response to nonself antigens." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002461 ! tolerance induction dependent upon immune response + +[Term] +id: GO:0002463 +name: central tolerance induction to nonself antigen +namespace: biological_process +def: "Tolerance induction to nonself antigens in the central lymphoid organs." [GOC:jal, PMID:12547504] +is_a: GO:0002462 ! tolerance induction to nonself antigen +is_a: GO:0002508 ! central tolerance induction + +[Term] +id: GO:0002464 +name: peripheral tolerance induction to nonself antigen +namespace: biological_process +def: "Tolerance induction to nonself antigens in the periphery." [GOC:jal, ISBN:0781735149] +is_a: GO:0002462 ! tolerance induction to nonself antigen +is_a: GO:0002465 ! peripheral tolerance induction + +[Term] +id: GO:0002465 +name: peripheral tolerance induction +namespace: biological_process +def: "Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002461 ! tolerance induction dependent upon immune response + +[Term] +id: GO:0002466 +name: peripheral tolerance induction to self antigen +namespace: biological_process +def: "Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues." [GOC:jal, ISBN:0781735149] +is_a: GO:0002465 ! peripheral tolerance induction +is_a: GO:0002513 ! tolerance induction to self antigen + +[Term] +id: GO:0002467 +name: germinal center formation +namespace: biological_process +def: "The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation." [GO_REF:0000022, GOC:jal, ISBN:081533642X] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0002468 +name: dendritic cell antigen processing and presentation +namespace: biological_process +def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002469 +name: myeloid dendritic cell antigen processing and presentation +namespace: biological_process +def: "The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002470 +name: plasmacytoid dendritic cell antigen processing and presentation +namespace: biological_process +def: "The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002471 +name: monocyte antigen processing and presentation +namespace: biological_process +def: "The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11200054] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002472 +name: macrophage antigen processing and presentation +namespace: biological_process +def: "The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002473 +name: non-professional antigen presenting cell antigen processing and presentation +namespace: biological_process +def: "The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002474 +name: antigen processing and presentation of peptide antigen via MHC class I +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591] +synonym: "peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002475 +name: antigen processing and presentation via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, PMID:15928678, PMID:15928680] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002476 +name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "endogenous peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib +is_a: GO:0002483 ! antigen processing and presentation of endogenous peptide antigen + +[Term] +id: GO:0002477 +name: antigen processing and presentation of exogenous peptide antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "exogenous peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib +is_a: GO:0002478 ! antigen processing and presentation of exogenous peptide antigen + +[Term] +id: GO:0002478 +name: antigen processing and presentation of exogenous peptide antigen +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell." [GOC:add, ISBN:0781735149] +synonym: "exogenous peptide antigen processing and presentation" EXACT [] +is_a: GO:0019884 ! antigen processing and presentation of exogenous antigen +is_a: GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002479 +name: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules." [GOC:add, PMID:15224093, PMID:15771591, PMID:16181335] +synonym: "cross presentation" BROAD [] +synonym: "cross-presentation" BROAD [] +synonym: "exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent" EXACT [] +synonym: "TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I" EXACT [] +synonym: "TAP-dependent exogenous peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0042590 ! antigen processing and presentation of exogenous peptide antigen via MHC class I + +[Term] +id: GO:0002480 +name: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules." [GOC:add, PMID:15224093, PMID:15771591, PMID:16181335] +synonym: "cross presentation" BROAD [] +synonym: "cross-presentation" BROAD [] +synonym: "exogenous peptide antigen processing and presentation via MHC class I, TAP-independent" EXACT [] +synonym: "TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I" EXACT [] +synonym: "TAP-independent exogenous peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0042590 ! antigen processing and presentation of exogenous peptide antigen via MHC class I + +[Term] +id: GO:0002481 +name: antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent" EXACT [] +synonym: "TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib" EXACT [] +synonym: "TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002477 ! antigen processing and presentation of exogenous peptide antigen via MHC class Ib + +[Term] +id: GO:0002482 +name: antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent" EXACT [] +synonym: "TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib" EXACT [] +synonym: "TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002477 ! antigen processing and presentation of exogenous peptide antigen via MHC class Ib + +[Term] +id: GO:0002483 +name: antigen processing and presentation of endogenous peptide antigen +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell." [GOC:add, ISBN:0781735149] +synonym: "endogenous peptide antigen processing and presentation" EXACT [] +is_a: GO:0019883 ! antigen processing and presentation of endogenous antigen +is_a: GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002484 +name: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:14647477, PMID:15771591] +synonym: "endogenous peptide antigen processing and presentation via MHC class I via ER pathway" EXACT [] +is_a: GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I + +[Term] +id: GO:0002485 +name: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:14647477, PMID:15771591] +synonym: "endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent" EXACT [] +synonym: "TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway" EXACT [] +synonym: "TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway" EXACT [] +is_a: GO:0002484 ! antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway + +[Term] +id: GO:0002486 +name: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules." [GOC:add, PMID:14647477, PMID:15771591] +synonym: "endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent" EXACT [] +synonym: "TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway" EXACT [] +synonym: "TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway" EXACT [] +is_a: GO:0002484 ! antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway + +[Term] +id: GO:0002487 +name: antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules." [GOC:add, PMID:10631943] +synonym: "endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway" EXACT [] +is_a: GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I + +[Term] +id: GO:0002488 +name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway" EXACT [] +is_a: GO:0002476 ! antigen processing and presentation of endogenous peptide antigen via MHC class Ib + +[Term] +id: GO:0002489 +name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent" EXACT [] +synonym: "TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway" EXACT [] +synonym: "TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway" EXACT [] +is_a: GO:0002488 ! antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway + +[Term] +id: GO:0002490 +name: antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +synonym: "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent" EXACT [] +synonym: "TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway" EXACT [] +synonym: "TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway" EXACT [] +is_a: GO:0002488 ! antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway + +[Term] +id: GO:0002491 +name: antigen processing and presentation of endogenous peptide antigen via MHC class II +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein." [GOC:add, PMID:15531770, PMID:16181338] +synonym: "endogenous peptide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002483 ! antigen processing and presentation of endogenous peptide antigen +is_a: GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0002492 +name: peptide antigen assembly with MHC class Ib protein complex +namespace: biological_process +def: "The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family." [GOC:add, PMID:15928678] +is_a: GO:0002501 ! peptide antigen assembly with MHC protein complex +relationship: part_of GO:0002398 ! MHC class Ib protein complex assembly +relationship: part_of GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib + +[Term] +id: GO:0002493 +name: lipid antigen assembly with MHC class Ib protein complex +namespace: biological_process +def: "The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family." [GOC:add, PMID:15928678, PMID:15928680] +is_a: GO:0065005 ! protein-lipid complex assembly +relationship: part_of GO:0002398 ! MHC class Ib protein complex assembly +relationship: part_of GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0002494 +name: lipid antigen transport +namespace: biological_process +def: "The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:add, PMID:15928678, PMID:15928680] +is_a: GO:0006869 ! lipid transport +relationship: part_of GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0002495 +name: antigen processing and presentation of peptide antigen via MHC class II +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591] +synonym: "peptide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002496 +name: proteolysis associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591] +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process +intersection_of: GO:0006508 ! proteolysis +intersection_of: part_of GO:0048002 ! antigen processing and presentation of peptide antigen +relationship: part_of GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002497 +name: proteasomal proteolysis associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591] +is_a: GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002498 +name: proteolysis within endoplasmic reticulum associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15224092, PMID:15771591] +synonym: "endoplasmic reticulum proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "ER proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "proteolysis within ER associated with antigen processing and presentation" EXACT [] +is_a: GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002499 +name: proteolysis within endosome associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "endosomal proteolysis associated with antigen processing and presentation" EXACT [] +is_a: GO:0002496 ! proteolysis associated with antigen processing and presentation +intersection_of: GO:0002496 ! proteolysis associated with antigen processing and presentation +intersection_of: occurs_in GO:0005768 ! endosome +relationship: occurs_in GO:0005768 ! endosome + +[Term] +id: GO:0002500 +name: proteolysis within lysosome associated with antigen processing and presentation +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "lysosomal proteolysis associated with antigen processing and presentation" EXACT [] +is_a: GO:0002496 ! proteolysis associated with antigen processing and presentation +intersection_of: GO:0002496 ! proteolysis associated with antigen processing and presentation +intersection_of: occurs_in GO:0005764 ! lysosome +relationship: occurs_in GO:0005764 ! lysosome + +[Term] +id: GO:0002501 +name: peptide antigen assembly with MHC protein complex +namespace: biological_process +def: "The binding of a peptide to the antigen binding groove of an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0002396 ! MHC protein complex assembly +relationship: part_of GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002502 +name: peptide antigen assembly with MHC class I protein complex +namespace: biological_process +def: "The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002501 ! peptide antigen assembly with MHC protein complex +relationship: part_of GO:0002397 ! MHC class I protein complex assembly +relationship: part_of GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I + +[Term] +id: GO:0002503 +name: peptide antigen assembly with MHC class II protein complex +namespace: biological_process +def: "The binding of a peptide to the antigen binding groove of an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0002501 ! peptide antigen assembly with MHC protein complex +relationship: part_of GO:0002399 ! MHC class II protein complex assembly +relationship: part_of GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0002504 +name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240] +synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002505 +name: antigen processing and presentation of polysaccharide antigen via MHC class II +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex." [GOC:add, PMID:16153240] +synonym: "polysaccharide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II + +[Term] +id: GO:0002507 +name: tolerance induction +namespace: biological_process +def: "A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0002520 ! immune system development + +[Term] +id: GO:0002508 +name: central tolerance induction +namespace: biological_process +def: "Tolerance induction in the central lymphoid organs: the thymus and bone marrow." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002509 +name: central tolerance induction to self antigen +namespace: biological_process +def: "Tolerance induction in the central lymphoid organs directed at self antigens." [GOC:jal, ISBN:0781735149, PMID:16460922] +is_a: GO:0002508 ! central tolerance induction +is_a: GO:0002513 ! tolerance induction to self antigen + +[Term] +id: GO:0002510 +name: central B cell tolerance induction +namespace: biological_process +def: "Tolerance induction of B cells in the bone marrow." [GOC:jal, PMID:16460922] +synonym: "central B lymphocyte tolerance induction" EXACT [] +synonym: "central B-cell tolerance induction" EXACT [] +synonym: "central B-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002508 ! central tolerance induction +is_a: GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002511 +name: central B cell receptor editing +namespace: biological_process +def: "Receptor editing occurring in B cells in the bone marrow." [GOC:jal, PMID:16460922] +synonym: "central B lymphocyte receptor editing" EXACT [] +synonym: "central B-cell receptor editing" EXACT [] +synonym: "central B-lymphocyte receptor editing" EXACT [] +is_a: GO:0002452 ! B cell receptor editing + +[Term] +id: GO:0002512 +name: central T cell tolerance induction +namespace: biological_process +def: "Tolerance induction of T cells in the thymus." [GOC:jal, ISBN:0781735149] +synonym: "central T lymphocyte tolerance induction" EXACT [] +synonym: "central T-cell tolerance induction" EXACT [] +synonym: "central T-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002508 ! central tolerance induction +is_a: GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002513 +name: tolerance induction to self antigen +namespace: biological_process +def: "Tolerance induction directed at self antigens." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002514 +name: B cell tolerance induction +namespace: biological_process +def: "A process involving any mechanism for tolerance induction in B cells." [GOC:jal, ISBN:0781735149, PMID:16460922] +synonym: "B lymphocyte tolerance induction" EXACT [] +synonym: "B-cell tolerance induction" EXACT [] +synonym: "B-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002515 +name: B cell anergy +namespace: biological_process +def: "Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction." [GOC:jal, ISBN:0781735149] +synonym: "B lymphocyte anergy" EXACT [] +synonym: "B-cell anergy" EXACT [] +synonym: "B-lymphocyte anergy" EXACT [] +is_a: GO:0002249 ! lymphocyte anergy +is_a: GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002516 +name: B cell deletion +namespace: biological_process +def: "The apoptotic death of B cells which is part of B cell tolerance induction." [GOC:add, GOC:jal, ISBN:0781735149] +synonym: "B lymphocyte deletion" EXACT [] +synonym: "B-cell deletion" EXACT [] +synonym: "B-lymphocyte deletion" EXACT [] +is_a: GO:0001783 ! B cell apoptotic process +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0001783 ! B cell apoptotic process +intersection_of: part_of GO:0002514 ! B cell tolerance induction +relationship: part_of GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002517 +name: T cell tolerance induction +namespace: biological_process +def: "A process involving any mechanism for tolerance induction in T cells." [GOC:jal, ISBN:0781735149, PMID:16551263] +synonym: "T lymphocyte tolerance induction" EXACT [] +synonym: "T-cell tolerance induction" EXACT [] +synonym: "T-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002518 +name: lymphocyte chemotaxis across high endothelial venule +namespace: biological_process +def: "The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus." [GOC:add, ISBN:0781735149, PMID:15122201] +is_a: GO:0048247 ! lymphocyte chemotaxis + +[Term] +id: GO:0002519 +name: natural killer cell tolerance induction +namespace: biological_process +def: "Tolerance induction of natural killer cells." [GOC:jal, PMID:16546094] +synonym: "NK cell tolerance induction" EXACT [] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0002520 +name: immune system development +namespace: biological_process +def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] +subset: goslim_drosophila +is_a: GO:0002376 ! immune system process +is_a: GO:0048731 ! system development + +[Term] +id: GO:0002521 +name: leukocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] +synonym: "immune cell differentiation" EXACT [] +synonym: "leucocyte differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030097 ! hemopoiesis + +[Term] +id: GO:0002522 +name: leukocyte migration involved in immune response +namespace: biological_process +def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +synonym: "immune cell migration during immune response" EXACT [] +synonym: "immune cell trafficking during immune response" EXACT [] +synonym: "leucocyte migration during immune response" EXACT [] +synonym: "leucocyte trafficking during immune response" EXACT [] +synonym: "leukocyte trafficking during immune response" EXACT [] +is_a: GO:0002252 ! immune effector process +is_a: GO:0050900 ! leukocyte migration +intersection_of: GO:0050900 ! leukocyte migration +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0006955 ! immune response + +[Term] +id: GO:0002523 +name: leukocyte migration involved in inflammatory response +namespace: biological_process +def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +synonym: "immune cell migration during inflammatory response" RELATED [] +synonym: "immune cell trafficking during inflammatory response" RELATED [] +synonym: "leucocyte migration during inflammatory response" RELATED [] +synonym: "leucocyte trafficking during inflammatory response" RELATED [] +synonym: "leukocyte migration during inflammatory response" RELATED [GOC:dph] +synonym: "leukocyte trafficking during inflammatory response" RELATED [] +is_a: GO:0050900 ! leukocyte migration +intersection_of: GO:0050900 ! leukocyte migration +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002524 +name: hypersensitivity +namespace: biological_process +def: "An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system." [GOC:jal, ISBN:0781735149] +synonym: "hypersensitivity response" RELATED [ISBN:0781735149] +xref: Wikipedia:Hypersensitivity +is_a: GO:0002438 ! acute inflammatory response to antigenic stimulus + +[Term] +id: GO:0002525 +name: acute inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma." [GOC:jal, PMID:16459497, PMID:9073326] +is_a: GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002526 +name: acute inflammatory response +namespace: biological_process +def: "Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response." [GO_REF:0000022, GOC:add, ISBN:0781735149] +is_a: GO:0006954 ! inflammatory response + +[Term] +id: GO:0002527 +name: vasodilation involved in acute inflammatory response +namespace: biological_process +def: "An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response." [GOC:jal] +synonym: "vasodilation during acute inflammatory response" RELATED [GOC:dph] +is_a: GO:0042311 ! vasodilation +intersection_of: GO:0042311 ! vasodilation +intersection_of: part_of GO:0002526 ! acute inflammatory response +relationship: part_of GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002528 +name: regulation of vascular permeability involved in acute inflammatory response +namespace: biological_process +def: "Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response." [GOC:jal] +synonym: "regulation of vascular permeability during acute inflammatory response" RELATED [GOC:dph] +is_a: GO:0043114 ! regulation of vascular permeability +intersection_of: GO:0043114 ! regulation of vascular permeability +intersection_of: part_of GO:0002526 ! acute inflammatory response +relationship: part_of GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002529 +name: regulation of plasma kallikrein-kinin cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade." [GOC:add] +is_a: GO:0002256 ! regulation of kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002353 ! plasma kallikrein-kinin cascade +relationship: regulates GO:0002353 ! plasma kallikrein-kinin cascade + +[Term] +id: GO:0002530 +name: regulation of systemic arterial blood pressure involved in acute-phase response +namespace: biological_process +def: "Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, ISBN:081533642X] +synonym: "blood pressure regulation during acute phase response" RELATED [] +synonym: "regulation of systemic arterial blood pressure during acute phase response" RELATED [GOC:tb] +is_a: GO:0003073 ! regulation of systemic arterial blood pressure +intersection_of: GO:0003073 ! regulation of systemic arterial blood pressure +intersection_of: part_of GO:0006953 ! acute-phase response +relationship: part_of GO:0006953 ! acute-phase response + +[Term] +id: GO:0002531 +name: regulation of heart contraction involved in acute-phase response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein." [GOC:jal, PMID:15642986, PMID:15834430] +synonym: "regulation of cardiac contraction during acute phase response" RELATED [] +synonym: "regulation of heart contraction during acute phase response" RELATED [GOC:tb] +is_a: GO:0008016 ! regulation of heart contraction +intersection_of: GO:0008016 ! regulation of heart contraction +intersection_of: part_of GO:0006953 ! acute-phase response +relationship: part_of GO:0006953 ! acute-phase response + +[Term] +id: GO:0002532 +name: production of molecular mediator involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] +synonym: "production of cellular mediator of acute inflammation" RELATED [] +synonym: "production of molecular mediator involved in acute inflammatory response" BROAD [] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002533 +name: lysosomal enzyme secretion involved in inflammatory response +namespace: biological_process +def: "The regulated release of lysosomal enzymes by a cell as part of an inflammatory response." [GOC:jal, PMID:11836514] +synonym: "lysosomal enzyme secretion involved in acute inflammatory response" RELATED [GOC:mah] +synonym: "secretion of lysosomal enzymes involved in acute inflammatory response" BROAD [] +synonym: "secretion of lysosomal enzymes involved in inflammatory response" EXACT [] +is_a: GO:0033299 ! secretion of lysosomal enzymes +intersection_of: GO:0033299 ! secretion of lysosomal enzymes +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0002393 ! lysosomal enzyme production involved in inflammatory response + +[Term] +id: GO:0002534 +name: cytokine production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "cytokine production involved in acute inflammatory response" BROAD [] +is_a: GO:0001816 ! cytokine production +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response +intersection_of: GO:0001816 ! cytokine production +intersection_of: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002535 +name: platelet activating factor secretion involved in inflammatory response +namespace: biological_process +def: "The regulated release of platelet activating factor by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] +synonym: "platelet activating factor secretion involved in acute inflammatory response" BROAD [] +is_a: GO:0002392 ! platelet activating factor secretion +intersection_of: GO:0002392 ! platelet activating factor secretion +intersection_of: part_of GO:0006954 ! inflammatory response +relationship: part_of GO:0002391 ! platelet activating factor production involved in inflammatory response + +[Term] +id: GO:0002536 +name: respiratory burst involved in inflammatory response +namespace: biological_process +def: "A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "oxidative burst during acute inflammatory response" BROAD [] +synonym: "production of reactive oxygen species during acute inflammatory response" BROAD [] +synonym: "respiratory burst involved in acute inflammatory response" BROAD [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response +is_a: GO:0002679 ! respiratory burst involved in defense response +intersection_of: GO:0045730 ! respiratory burst +intersection_of: part_of GO:0006954 ! inflammatory response + +[Term] +id: GO:0002537 +name: nitric oxide production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "nitric oxide production involved in acute inflammatory response" BROAD [GOC:mah] +synonym: "production of nitric oxide involved in acute inflammatory response" BROAD [] +synonym: "production of nitric oxide involved in inflammatory response" EXACT [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response + +[Term] +id: GO:0002538 +name: arachidonic acid metabolite production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "arachidonic acid metabolite production involved in acute inflammatory response" BROAD [GOC:mah] +synonym: "production of arachidonic acid metabolites involved in acute inflammatory response" BROAD [] +synonym: "production of arachidonic acid metabolites involved in inflammatory response" EXACT [] +is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response + +[Term] +id: GO:0002539 +name: prostaglandin production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "prostaglandin production involved in acute inflammatory response" BROAD [] +is_a: GO:0002538 ! arachidonic acid metabolite production involved in inflammatory response + +[Term] +id: GO:0002540 +name: leukotriene production involved in inflammatory response +namespace: biological_process +def: "The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] +synonym: "leukotriene production involved in acute inflammatory response" BROAD [] +is_a: GO:0002538 ! arachidonic acid metabolite production involved in inflammatory response + +[Term] +id: GO:0002541 +name: activation of plasma proteins involved in acute inflammatory response +namespace: biological_process +def: "Any process activating plasma proteins by proteolysis as part of an acute inflammatory response." [GOC:jal, ISBN:0781735149] +is_a: GO:0016485 ! protein processing +relationship: part_of GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002542 +name: Factor XII activation +namespace: biological_process +def: "Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade." [GOC:jal, ISBN:0721601871] +synonym: "Hageman factor activation" EXACT [] +is_a: GO:0002675 ! positive regulation of acute inflammatory response +is_a: GO:0010954 ! positive regulation of protein processing +relationship: part_of GO:0002353 ! plasma kallikrein-kinin cascade +relationship: positively_regulates GO:0002541 ! activation of plasma proteins involved in acute inflammatory response + +[Term] +id: GO:0002543 +name: activation of blood coagulation via clotting cascade +namespace: biological_process +def: "Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot." [GOC:jal, ISBN:0781735149] +synonym: "activation of clotting cascade" EXACT [] +is_a: GO:0030194 ! positive regulation of blood coagulation +relationship: part_of GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002544 +name: chronic inflammatory response +namespace: biological_process +def: "Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response." [GO_REF:0000022, GOC:jal, ISBN:0781735149] +is_a: GO:0006954 ! inflammatory response + +[Term] +id: GO:0002545 +name: chronic inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma." [GOC:jal] +is_a: GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002546 +name: negative regulation of tissue kallikrein-kinin cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade." [GOC:add] +synonym: "down regulation of tissue kallikrein-kinin cascade" EXACT [] +synonym: "down-regulation of tissue kallikrein-kinin cascade" EXACT [] +synonym: "downregulation of tissue kallikrein-kinin cascade" EXACT [] +synonym: "inhibition of tissue kallikrein-kinin cascade" NARROW [] +synonym: "negative regulation of glandular kallikrein-kinin cascade" EXACT [] +is_a: GO:0002257 ! negative regulation of kinin cascade +is_a: GO:0002382 ! regulation of tissue kallikrein-kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002255 ! tissue kallikrein-kinin cascade +relationship: negatively_regulates GO:0002255 ! tissue kallikrein-kinin cascade + +[Term] +id: GO:0002547 +name: positive regulation of tissue kallikrein-kinin cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade." [GOC:add] +synonym: "activation of tissue kallikrein-kinin cascade" NARROW [] +synonym: "positive regulation of glandular kallikrein-kinin cascade" EXACT [] +synonym: "stimulation of tissue kallikrein-kinin cascade" NARROW [] +synonym: "up regulation of tissue kallikrein-kinin cascade" EXACT [] +synonym: "up-regulation of tissue kallikrein-kinin cascade" EXACT [] +synonym: "upregulation of tissue kallikrein-kinin cascade" EXACT [] +is_a: GO:0002258 ! positive regulation of kinin cascade +is_a: GO:0002382 ! regulation of tissue kallikrein-kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002255 ! tissue kallikrein-kinin cascade +relationship: positively_regulates GO:0002255 ! tissue kallikrein-kinin cascade + +[Term] +id: GO:0002548 +name: monocyte chemotaxis +namespace: biological_process +def: "The movement of a monocyte in response to an external stimulus." [GOC:add, PMID:11696603, PMID:15173832] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:0071674 ! mononuclear cell migration +is_a: GO:0097529 ! myeloid leukocyte migration + +[Term] +id: GO:0002549 +name: negative regulation of plasma kallikrein-kinin cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade." [GOC:add] +synonym: "down regulation of plasma kallikrein-kinin cascade" EXACT [] +synonym: "down-regulation of plasma kallikrein-kinin cascade" EXACT [] +synonym: "downregulation of plasma kallikrein-kinin cascade" EXACT [] +synonym: "inhibition of plasma kallikrein-kinin cascade" NARROW [] +is_a: GO:0002257 ! negative regulation of kinin cascade +is_a: GO:0002529 ! regulation of plasma kallikrein-kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002353 ! plasma kallikrein-kinin cascade +relationship: negatively_regulates GO:0002353 ! plasma kallikrein-kinin cascade + +[Term] +id: GO:0002550 +name: positive regulation of plasma kallikrein-kinin cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade." [GOC:add] +synonym: "activation of plasma kallikrein-kinin cascade" NARROW [] +synonym: "stimulation of plasma kallikrein-kinin cascade" NARROW [] +synonym: "up regulation of plasma kallikrein-kinin cascade" EXACT [] +synonym: "up-regulation of plasma kallikrein-kinin cascade" EXACT [] +synonym: "upregulation of plasma kallikrein-kinin cascade" EXACT [] +is_a: GO:0002258 ! positive regulation of kinin cascade +is_a: GO:0002529 ! regulation of plasma kallikrein-kinin cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002353 ! plasma kallikrein-kinin cascade +relationship: positively_regulates GO:0002353 ! plasma kallikrein-kinin cascade + +[Term] +id: GO:0002551 +name: mast cell chemotaxis +namespace: biological_process +def: "The movement of a mast cell in response to an external stimulus." [GOC:add, PMID:11292027, PMID:12789214, PMID:16448392] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:0097531 ! mast cell migration + +[Term] +id: GO:0002552 +name: serotonin secretion by mast cell +namespace: biological_process +def: "The regulated release of serotonin by a mast cell or group of mast cells." [GOC:add, ISBN:0781735149] +synonym: "serotonin release by mast cell" RELATED [GOC:tb] +is_a: GO:0002442 ! serotonin secretion involved in inflammatory response +is_a: GO:0046907 ! intracellular transport +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0043303 ! mast cell degranulation + +[Term] +id: GO:0002553 +name: histamine secretion by mast cell +namespace: biological_process +def: "The regulated release of histamine by a mast cell or group of mast cells." [GOC:add, ISBN:0781735149] +is_a: GO:0002441 ! histamine secretion involved in inflammatory response +is_a: GO:0046907 ! intracellular transport +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0043303 ! mast cell degranulation + +[Term] +id: GO:0002554 +name: serotonin secretion by platelet +namespace: biological_process +def: "The regulated release of serotonin by a platelet or group of platelets." [GOC:add, ISBN:0781735149] +synonym: "serotonin release by platelet" RELATED [GOC:tb] +is_a: GO:0002442 ! serotonin secretion involved in inflammatory response +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0002576 ! platelet degranulation + +[Term] +id: GO:0002555 +name: histamine secretion by platelet +namespace: biological_process +def: "The regulated release of histamine by a platelet or group of platelets." [GOC:add, PMID:9117517] +is_a: GO:0002441 ! histamine secretion involved in inflammatory response +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0002576 ! platelet degranulation + +[Term] +id: GO:0002556 +name: serotonin secretion by basophil +namespace: biological_process +def: "The regulated release of serotonin by a basophil or group of basophils." [GOC:add, ISBN:0781735149] +synonym: "serotonin release by basophil" RELATED [GOC:tb] +is_a: GO:0002442 ! serotonin secretion involved in inflammatory response +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0002561 ! basophil degranulation + +[Term] +id: GO:0002557 +name: histamine secretion by basophil +namespace: biological_process +def: "The regulated release of histamine by a basophil or group of basophils." [GOC:add, ISBN:0781735149] +is_a: GO:0002441 ! histamine secretion involved in inflammatory response +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0002561 ! basophil degranulation + +[Term] +id: GO:0002558 +name: type I hypersensitivity mediated by mast cells +namespace: biological_process +def: "An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines." [GOC:add, ISBN:0781735149] +is_a: GO:0002448 ! mast cell mediated immunity +is_a: GO:0016068 ! type I hypersensitivity + +[Term] +id: GO:0002559 +name: type I hypersensitivity mediated by basophils +namespace: biological_process +def: "An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines." [GOC:add, ISBN:0781735149] +is_a: GO:0002560 ! basophil mediated immunity +is_a: GO:0016068 ! type I hypersensitivity + +[Term] +id: GO:0002560 +name: basophil mediated immunity +namespace: biological_process +def: "Any process involved in the carrying out of an immune response by a basophil." [GOC:add, ISBN:0781735149] +is_a: GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002561 +name: basophil degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil." [GOC:add, ISBN:0781735149] +is_a: GO:0002276 ! basophil activation involved in immune response +is_a: GO:0043299 ! leukocyte degranulation +relationship: part_of GO:0002560 ! basophil mediated immunity + +[Term] +id: GO:0002562 +name: somatic diversification of immune receptors via germline recombination within a single locus +namespace: biological_process +def: "The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus." [GOC:add, ISBN:0781735149, PMID:16102575, PMID:16166509] +is_a: GO:0002200 ! somatic diversification of immune receptors +is_a: GO:0016444 ! somatic cell DNA recombination + +[Term] +id: GO:0002563 +name: somatic diversification of immune receptors via alternate splicing +namespace: biological_process +def: "The process in which immune receptor genes are diversified through alternate splicing." [GOC:add, ISBN:0781735149, PMID:16166509] +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002564 +name: alternate splicing of immunoglobulin genes +namespace: biological_process +def: "The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons." [ISBN:0781735149, PMID:9185563] +synonym: "alternate splicing of antibody genes" EXACT [] +is_a: GO:0002563 ! somatic diversification of immune receptors via alternate splicing +is_a: GO:0016445 ! somatic diversification of immunoglobulins + +[Term] +id: GO:0002565 +name: somatic diversification of immune receptors via gene conversion +namespace: biological_process +def: "The process in which immune receptor genes are diversified through gene conversion." [GOC:add, ISBN:0781735149] +is_a: GO:0002200 ! somatic diversification of immune receptors +is_a: GO:0016444 ! somatic cell DNA recombination + +[Term] +id: GO:0002566 +name: somatic diversification of immune receptors via somatic mutation +namespace: biological_process +def: "The process in which immune receptor genes are diversified through somatic mutation." [ISBN:0781735149, PMID:16102575] +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002567 +name: somatic diversification of FREP-based immune receptors +namespace: biological_process +def: "The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails." [GOC:add, PMID:16102575] +comment: Note that this type of immune receptor has been found in snails (Pulmonata, ncbi_axonomy_id:6519), but may also be seen in other species. +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002568 +name: somatic diversification of T cell receptor genes +namespace: biological_process +def: "The somatic process that results in the generation of sequence diversity of T cell receptor genes." [GOC:add, ISBN:0781735149] +synonym: "somatic diversification of TCR genes" EXACT [] +is_a: GO:0002200 ! somatic diversification of immune receptors +relationship: part_of GO:0030217 ! T cell differentiation + +[Term] +id: GO:0002569 +name: somatic diversification of immune receptors by N region addition +namespace: biological_process +def: "The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene." [GOC:add, ISBN:0781735149] +is_a: GO:0002200 ! somatic diversification of immune receptors + +[Term] +id: GO:0002570 +name: somatic diversification of immunoglobulin genes by N region addition +namespace: biological_process +def: "The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions." [GOC:add, ISBN:0781735149] +synonym: "somatic diversification of antibody genes by N region addition" EXACT [] +is_a: GO:0002569 ! somatic diversification of immune receptors by N region addition +is_a: GO:0016445 ! somatic diversification of immunoglobulins +relationship: part_of GO:0016447 ! somatic recombination of immunoglobulin gene segments + +[Term] +id: GO:0002571 +name: somatic diversification of T cell receptor genes by N region addition +namespace: biological_process +def: "The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene." [GOC:add, ISBN:0781735149] +synonym: "somatic diversification of TCR genes by N region addition" EXACT [] +is_a: GO:0002568 ! somatic diversification of T cell receptor genes +is_a: GO:0002569 ! somatic diversification of immune receptors by N region addition +relationship: part_of GO:0002681 ! somatic recombination of T cell receptor gene segments + +[Term] +id: GO:0002572 +name: pro-T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149] +synonym: "pro-T lymphocyte differentiation" EXACT [] +is_a: GO:0002320 ! lymphoid progenitor cell differentiation +relationship: part_of GO:0030217 ! T cell differentiation + +[Term] +id: GO:0002573 +name: myeloid leukocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251] +synonym: "myeloid leucocyte differentiation" EXACT [] +is_a: GO:0002521 ! leukocyte differentiation +is_a: GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0002574 +name: thrombocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis." [GOC:add] +comment: Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220. +is_a: GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0002575 +name: basophil chemotaxis +namespace: biological_process +def: "The movement of a basophil in response to an external stimulus." [GOC:add, PMID:11292027] +is_a: GO:0071621 ! granulocyte chemotaxis + +[Term] +id: GO:0002576 +name: platelet degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet." [GOC:add] +synonym: "platelet exocytosis" EXACT [] +is_a: GO:0045055 ! regulated exocytosis +is_a: GO:0051649 ! establishment of localization in cell + +[Term] +id: GO:0002577 +name: regulation of antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add] +is_a: GO:0002682 ! regulation of immune system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019882 ! antigen processing and presentation +relationship: regulates GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002578 +name: negative regulation of antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add] +synonym: "down regulation of antigen processing and presentation" EXACT [] +synonym: "down-regulation of antigen processing and presentation" EXACT [] +synonym: "downregulation of antigen processing and presentation" EXACT [] +synonym: "inhibition of antigen processing and presentation" NARROW [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +is_a: GO:0002683 ! negative regulation of immune system process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019882 ! antigen processing and presentation +relationship: negatively_regulates GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002579 +name: positive regulation of antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add] +synonym: "activation of antigen processing and presentation" NARROW [] +synonym: "stimulation of antigen processing and presentation" NARROW [] +synonym: "up regulation of antigen processing and presentation" EXACT [] +synonym: "up-regulation of antigen processing and presentation" EXACT [] +synonym: "upregulation of antigen processing and presentation" EXACT [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +is_a: GO:0002684 ! positive regulation of immune system process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019882 ! antigen processing and presentation +relationship: positively_regulates GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002580 +name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] +synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +relationship: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II + +[Term] +id: GO:0002581 +name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] +synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +synonym: "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] +synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +relationship: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II + +[Term] +id: GO:0002582 +name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] +synonym: "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] +synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] +synonym: "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] +synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +relationship: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II + +[Term] +id: GO:0002583 +name: regulation of antigen processing and presentation of peptide antigen +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen." [GOC:add] +synonym: "regulation of peptide antigen processing and presentation" EXACT [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048002 ! antigen processing and presentation of peptide antigen +relationship: regulates GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002584 +name: negative regulation of antigen processing and presentation of peptide antigen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen." [GOC:add] +synonym: "down regulation of antigen processing and presentation of peptide antigen" EXACT [] +synonym: "down-regulation of antigen processing and presentation of peptide antigen" EXACT [] +synonym: "downregulation of antigen processing and presentation of peptide antigen" EXACT [] +synonym: "inhibition of antigen processing and presentation of peptide antigen" NARROW [] +synonym: "negative regulation of peptide antigen processing and presentation" EXACT [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048002 ! antigen processing and presentation of peptide antigen +relationship: negatively_regulates GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002585 +name: positive regulation of antigen processing and presentation of peptide antigen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen." [GOC:add] +synonym: "activation of antigen processing and presentation of peptide antigen" NARROW [] +synonym: "positive regulation of peptide antigen processing and presentation" EXACT [] +synonym: "stimulation of antigen processing and presentation of peptide antigen" NARROW [] +synonym: "up regulation of antigen processing and presentation of peptide antigen" EXACT [] +synonym: "up-regulation of antigen processing and presentation of peptide antigen" EXACT [] +synonym: "upregulation of antigen processing and presentation of peptide antigen" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048002 ! antigen processing and presentation of peptide antigen +relationship: positively_regulates GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0002586 +name: regulation of antigen processing and presentation of peptide antigen via MHC class II +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II." [GOC:add] +synonym: "regulation of peptide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II +relationship: regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0002587 +name: negative regulation of antigen processing and presentation of peptide antigen via MHC class II +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II." [GOC:add] +synonym: "down regulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +synonym: "down-regulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +synonym: "downregulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +synonym: "inhibition of antigen processing and presentation of peptide antigen via MHC class II" NARROW [] +synonym: "negative regulation of peptide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002581 ! negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002586 ! regulation of antigen processing and presentation of peptide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II +relationship: negatively_regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0002588 +name: positive regulation of antigen processing and presentation of peptide antigen via MHC class II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II." [GOC:add] +synonym: "activation of antigen processing and presentation of peptide antigen via MHC class II" NARROW [] +synonym: "positive regulation of peptide antigen processing and presentation via MHC class II" EXACT [] +synonym: "stimulation of antigen processing and presentation of peptide antigen via MHC class II" NARROW [] +synonym: "up regulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +synonym: "up-regulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +synonym: "upregulation of antigen processing and presentation of peptide antigen via MHC class II" EXACT [] +is_a: GO:0002582 ! positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002586 ! regulation of antigen processing and presentation of peptide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II +relationship: positively_regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0002589 +name: regulation of antigen processing and presentation of peptide antigen via MHC class I +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I." [GOC:add] +synonym: "regulation of peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +relationship: regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I + +[Term] +id: GO:0002590 +name: negative regulation of antigen processing and presentation of peptide antigen via MHC class I +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I." [GOC:add] +synonym: "down regulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +synonym: "down-regulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +synonym: "downregulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +synonym: "inhibition of antigen processing and presentation of peptide antigen via MHC class I" NARROW [] +synonym: "negative regulation of peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002589 ! regulation of antigen processing and presentation of peptide antigen via MHC class I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +relationship: negatively_regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I + +[Term] +id: GO:0002591 +name: positive regulation of antigen processing and presentation of peptide antigen via MHC class I +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I." [GOC:add] +synonym: "activation of antigen processing and presentation of peptide antigen via MHC class I" NARROW [] +synonym: "positive regulation of peptide antigen processing and presentation via MHC class I" EXACT [] +synonym: "stimulation of antigen processing and presentation of peptide antigen via MHC class I" NARROW [] +synonym: "up regulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +synonym: "up-regulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +synonym: "upregulation of antigen processing and presentation of peptide antigen via MHC class I" EXACT [] +is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002589 ! regulation of antigen processing and presentation of peptide antigen via MHC class I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +relationship: positively_regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I + +[Term] +id: GO:0002592 +name: regulation of antigen processing and presentation via MHC class Ib +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib." [GOC:add] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002475 ! antigen processing and presentation via MHC class Ib +relationship: regulates GO:0002475 ! antigen processing and presentation via MHC class Ib + +[Term] +id: GO:0002593 +name: negative regulation of antigen processing and presentation via MHC class Ib +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib." [GOC:add] +synonym: "down regulation of antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "down-regulation of antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "downregulation of antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "inhibition of antigen processing and presentation via MHC class Ib" NARROW [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002592 ! regulation of antigen processing and presentation via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002475 ! antigen processing and presentation via MHC class Ib +relationship: negatively_regulates GO:0002475 ! antigen processing and presentation via MHC class Ib + +[Term] +id: GO:0002594 +name: positive regulation of antigen processing and presentation via MHC class Ib +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib." [GOC:add] +synonym: "activation of antigen processing and presentation via MHC class Ib" NARROW [] +synonym: "stimulation of antigen processing and presentation via MHC class Ib" NARROW [] +synonym: "up regulation of antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "up-regulation of antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "upregulation of antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002592 ! regulation of antigen processing and presentation via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002475 ! antigen processing and presentation via MHC class Ib +relationship: positively_regulates GO:0002475 ! antigen processing and presentation via MHC class Ib + +[Term] +id: GO:0002595 +name: regulation of antigen processing and presentation of peptide antigen via MHC class Ib +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib." [GOC:add] +synonym: "regulation of peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002592 ! regulation of antigen processing and presentation via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib +relationship: regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib + +[Term] +id: GO:0002596 +name: negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib." [GOC:add] +synonym: "down regulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +synonym: "down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +synonym: "downregulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +synonym: "inhibition of antigen processing and presentation of peptide antigen via MHC class Ib" NARROW [] +synonym: "negative regulation of peptide antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002593 ! negative regulation of antigen processing and presentation via MHC class Ib +is_a: GO:0002595 ! regulation of antigen processing and presentation of peptide antigen via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib +relationship: negatively_regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib + +[Term] +id: GO:0002597 +name: positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib." [GOC:add] +synonym: "activation of antigen processing and presentation of peptide antigen via MHC class Ib" NARROW [] +synonym: "positive regulation of peptide antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "stimulation of antigen processing and presentation of peptide antigen via MHC class Ib" NARROW [] +synonym: "up regulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +synonym: "up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +synonym: "upregulation of antigen processing and presentation of peptide antigen via MHC class Ib" EXACT [] +is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002594 ! positive regulation of antigen processing and presentation via MHC class Ib +is_a: GO:0002595 ! regulation of antigen processing and presentation of peptide antigen via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib +relationship: positively_regulates GO:0002428 ! antigen processing and presentation of peptide antigen via MHC class Ib + +[Term] +id: GO:0002598 +name: regulation of antigen processing and presentation of lipid antigen via MHC class Ib +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib." [GOC:add] +synonym: "regulation of lipid antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002592 ! regulation of antigen processing and presentation via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib +relationship: regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0002599 +name: negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib." [GOC:add] +synonym: "down regulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +synonym: "down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +synonym: "downregulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +synonym: "inhibition of antigen processing and presentation of lipid antigen via MHC class Ib" NARROW [] +synonym: "negative regulation of lipid antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002593 ! negative regulation of antigen processing and presentation via MHC class Ib +is_a: GO:0002598 ! regulation of antigen processing and presentation of lipid antigen via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib +relationship: negatively_regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0002600 +name: positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib." [GOC:add] +synonym: "activation of antigen processing and presentation of lipid antigen via MHC class Ib" NARROW [] +synonym: "positive regulation of lipid antigen processing and presentation via MHC class Ib" EXACT [] +synonym: "stimulation of antigen processing and presentation of lipid antigen via MHC class Ib" NARROW [] +synonym: "up regulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +synonym: "up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +synonym: "upregulation of antigen processing and presentation of lipid antigen via MHC class Ib" EXACT [] +is_a: GO:0002594 ! positive regulation of antigen processing and presentation via MHC class Ib +is_a: GO:0002598 ! regulation of antigen processing and presentation of lipid antigen via MHC class Ib +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib +relationship: positively_regulates GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0002601 +name: regulation of antigen processing and presentation of polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II." [GOC:add] +synonym: "regulation of polysaccharide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II +relationship: regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II + +[Term] +id: GO:0002602 +name: negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II." [GOC:add] +synonym: "down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +synonym: "down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +synonym: "downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +synonym: "inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II" NARROW [] +synonym: "negative regulation of polysaccharide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002581 ! negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0002601 ! regulation of antigen processing and presentation of polysaccharide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II +relationship: negatively_regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II + +[Term] +id: GO:0002603 +name: positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II." [GOC:add] +synonym: "activation of antigen processing and presentation of polysaccharide antigen via MHC class II" NARROW [] +synonym: "positive regulation of polysaccharide antigen processing and presentation via MHC class II" EXACT [] +synonym: "stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II" NARROW [] +synonym: "up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +synonym: "up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +synonym: "upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II" EXACT [] +is_a: GO:0002582 ! positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II +is_a: GO:0002601 ! regulation of antigen processing and presentation of polysaccharide antigen via MHC class II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II +relationship: positively_regulates GO:0002505 ! antigen processing and presentation of polysaccharide antigen via MHC class II + +[Term] +id: GO:0002604 +name: regulation of dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002468 ! dendritic cell antigen processing and presentation +relationship: regulates GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002605 +name: negative regulation of dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT [] +synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT [] +synonym: "inhibition of dendritic cell antigen processing and presentation" NARROW [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation +relationship: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002606 +name: positive regulation of dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] +synonym: "activation of dendritic cell antigen processing and presentation" NARROW [] +synonym: "stimulation of dendritic cell antigen processing and presentation" NARROW [] +synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT [] +synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation +relationship: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation + +[Term] +id: GO:0002607 +name: regulation of myeloid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." [GOC:add] +is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation +relationship: regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002608 +name: negative regulation of myeloid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +synonym: "downregulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +synonym: "inhibition of myeloid dendritic cell antigen processing and presentation" NARROW [] +is_a: GO:0002605 ! negative regulation of dendritic cell antigen processing and presentation +is_a: GO:0002607 ! regulation of myeloid dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation +relationship: negatively_regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002609 +name: positive regulation of myeloid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation." [GOC:add] +synonym: "activation of myeloid dendritic cell antigen processing and presentation" NARROW [] +synonym: "stimulation of myeloid dendritic cell antigen processing and presentation" NARROW [] +synonym: "up regulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +synonym: "upregulation of myeloid dendritic cell antigen processing and presentation" EXACT [] +is_a: GO:0002606 ! positive regulation of dendritic cell antigen processing and presentation +is_a: GO:0002607 ! regulation of myeloid dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation +relationship: positively_regulates GO:0002469 ! myeloid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002610 +name: regulation of plasmacytoid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation." [GOC:add] +is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation +relationship: regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002611 +name: negative regulation of plasmacytoid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +synonym: "downregulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +synonym: "inhibition of plasmacytoid dendritic cell antigen processing and presentation" NARROW [] +is_a: GO:0002605 ! negative regulation of dendritic cell antigen processing and presentation +is_a: GO:0002610 ! regulation of plasmacytoid dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation +relationship: negatively_regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002612 +name: positive regulation of plasmacytoid dendritic cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation." [GOC:add] +synonym: "activation of plasmacytoid dendritic cell antigen processing and presentation" NARROW [] +synonym: "stimulation of plasmacytoid dendritic cell antigen processing and presentation" NARROW [] +synonym: "up regulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +synonym: "upregulation of plasmacytoid dendritic cell antigen processing and presentation" EXACT [] +is_a: GO:0002606 ! positive regulation of dendritic cell antigen processing and presentation +is_a: GO:0002610 ! regulation of plasmacytoid dendritic cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation +relationship: positively_regulates GO:0002470 ! plasmacytoid dendritic cell antigen processing and presentation + +[Term] +id: GO:0002613 +name: regulation of monocyte antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation." [GOC:add] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002471 ! monocyte antigen processing and presentation +relationship: regulates GO:0002471 ! monocyte antigen processing and presentation + +[Term] +id: GO:0002614 +name: negative regulation of monocyte antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation." [GOC:add] +synonym: "down regulation of monocyte antigen processing and presentation" EXACT [] +synonym: "down-regulation of monocyte antigen processing and presentation" EXACT [] +synonym: "downregulation of monocyte antigen processing and presentation" EXACT [] +synonym: "inhibition of monocyte antigen processing and presentation" NARROW [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002613 ! regulation of monocyte antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002471 ! monocyte antigen processing and presentation +relationship: negatively_regulates GO:0002471 ! monocyte antigen processing and presentation + +[Term] +id: GO:0002615 +name: positive regulation of monocyte antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation." [GOC:add] +synonym: "activation of monocyte antigen processing and presentation" NARROW [] +synonym: "stimulation of monocyte antigen processing and presentation" NARROW [] +synonym: "up regulation of monocyte antigen processing and presentation" EXACT [] +synonym: "up-regulation of monocyte antigen processing and presentation" EXACT [] +synonym: "upregulation of monocyte antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002613 ! regulation of monocyte antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002471 ! monocyte antigen processing and presentation +relationship: positively_regulates GO:0002471 ! monocyte antigen processing and presentation + +[Term] +id: GO:0002616 +name: regulation of macrophage antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation." [GOC:add] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002472 ! macrophage antigen processing and presentation +relationship: regulates GO:0002472 ! macrophage antigen processing and presentation + +[Term] +id: GO:0002617 +name: negative regulation of macrophage antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation." [GOC:add] +synonym: "down regulation of macrophage antigen processing and presentation" EXACT [] +synonym: "down-regulation of macrophage antigen processing and presentation" EXACT [] +synonym: "downregulation of macrophage antigen processing and presentation" EXACT [] +synonym: "inhibition of macrophage antigen processing and presentation" NARROW [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002616 ! regulation of macrophage antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002472 ! macrophage antigen processing and presentation +relationship: negatively_regulates GO:0002472 ! macrophage antigen processing and presentation + +[Term] +id: GO:0002618 +name: positive regulation of macrophage antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation." [GOC:add] +synonym: "activation of macrophage antigen processing and presentation" NARROW [] +synonym: "stimulation of macrophage antigen processing and presentation" NARROW [] +synonym: "up regulation of macrophage antigen processing and presentation" EXACT [] +synonym: "up-regulation of macrophage antigen processing and presentation" EXACT [] +synonym: "upregulation of macrophage antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002616 ! regulation of macrophage antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002472 ! macrophage antigen processing and presentation +relationship: positively_regulates GO:0002472 ! macrophage antigen processing and presentation + +[Term] +id: GO:0002619 +name: regulation of non-professional antigen presenting cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation." [GOC:add] +is_a: GO:0002577 ! regulation of antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation +relationship: regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation + +[Term] +id: GO:0002620 +name: negative regulation of non-professional antigen presenting cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +synonym: "downregulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +synonym: "inhibition of non-professional antigen presenting cell antigen processing and presentation" NARROW [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002619 ! regulation of non-professional antigen presenting cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation +relationship: negatively_regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation + +[Term] +id: GO:0002621 +name: positive regulation of non-professional antigen presenting cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation." [GOC:add] +synonym: "activation of non-professional antigen presenting cell antigen processing and presentation" NARROW [] +synonym: "stimulation of non-professional antigen presenting cell antigen processing and presentation" NARROW [] +synonym: "up regulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +synonym: "upregulation of non-professional antigen presenting cell antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002619 ! regulation of non-professional antigen presenting cell antigen processing and presentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation +relationship: positively_regulates GO:0002473 ! non-professional antigen presenting cell antigen processing and presentation + +[Term] +id: GO:0002622 +name: regulation of B cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation." [GOC:add] +synonym: "regulation of B lymphocyte antigen processing and presentation" EXACT [] +synonym: "regulation of B-cell antigen processing and presentation" EXACT [] +synonym: "regulation of B-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +is_a: GO:0002712 ! regulation of B cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002450 ! B cell antigen processing and presentation +relationship: regulates GO:0002450 ! B cell antigen processing and presentation + +[Term] +id: GO:0002623 +name: negative regulation of B cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of B cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of B cell antigen processing and presentation" EXACT [] +synonym: "downregulation of B cell antigen processing and presentation" EXACT [] +synonym: "inhibition of B cell antigen processing and presentation" NARROW [] +synonym: "negative regulation of B lymphocyte antigen processing and presentation" EXACT [] +synonym: "negative regulation of B-cell antigen processing and presentation" EXACT [] +synonym: "negative regulation of B-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002622 ! regulation of B cell antigen processing and presentation +is_a: GO:0002713 ! negative regulation of B cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002450 ! B cell antigen processing and presentation +relationship: negatively_regulates GO:0002450 ! B cell antigen processing and presentation + +[Term] +id: GO:0002624 +name: positive regulation of B cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation." [GOC:add] +synonym: "activation of B cell antigen processing and presentation" NARROW [] +synonym: "positive regulation of B lymphocyte antigen processing and presentation" EXACT [] +synonym: "positive regulation of B-cell antigen processing and presentation" EXACT [] +synonym: "positive regulation of B-lymphocyte antigen processing and presentation" EXACT [] +synonym: "stimulation of B cell antigen processing and presentation" NARROW [] +synonym: "up regulation of B cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of B cell antigen processing and presentation" EXACT [] +synonym: "upregulation of B cell antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002622 ! regulation of B cell antigen processing and presentation +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002450 ! B cell antigen processing and presentation +relationship: positively_regulates GO:0002450 ! B cell antigen processing and presentation + +[Term] +id: GO:0002625 +name: regulation of T cell antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] +synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT [] +synonym: "regulation of T-cell antigen processing and presentation" EXACT [] +synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0002577 ! regulation of antigen processing and presentation +is_a: GO:0002709 ! regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002457 ! T cell antigen processing and presentation +relationship: regulates GO:0002457 ! T cell antigen processing and presentation + +[Term] +id: GO:0002626 +name: negative regulation of T cell antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] +synonym: "down regulation of T cell antigen processing and presentation" EXACT [] +synonym: "down-regulation of T cell antigen processing and presentation" EXACT [] +synonym: "downregulation of T cell antigen processing and presentation" EXACT [] +synonym: "inhibition of T cell antigen processing and presentation" NARROW [] +synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT [] +synonym: "negative regulation of T-cell antigen processing and presentation" EXACT [] +synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT [] +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0002625 ! regulation of T cell antigen processing and presentation +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002457 ! T cell antigen processing and presentation +relationship: negatively_regulates GO:0002457 ! T cell antigen processing and presentation + +[Term] +id: GO:0002627 +name: positive regulation of T cell antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] +synonym: "activation of T cell antigen processing and presentation" NARROW [] +synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT [] +synonym: "positive regulation of T-cell antigen processing and presentation" EXACT [] +synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT [] +synonym: "stimulation of T cell antigen processing and presentation" NARROW [] +synonym: "up regulation of T cell antigen processing and presentation" EXACT [] +synonym: "up-regulation of T cell antigen processing and presentation" EXACT [] +synonym: "upregulation of T cell antigen processing and presentation" EXACT [] +is_a: GO:0002579 ! positive regulation of antigen processing and presentation +is_a: GO:0002625 ! regulation of T cell antigen processing and presentation +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002457 ! T cell antigen processing and presentation +relationship: positively_regulates GO:0002457 ! T cell antigen processing and presentation + +[Term] +id: GO:0002628 +name: regulation of proteolysis associated with antigen processing and presentation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +is_a: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002496 ! proteolysis associated with antigen processing and presentation +relationship: regulates GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002629 +name: negative regulation of proteolysis associated with antigen processing and presentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] +synonym: "down regulation of proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "down-regulation of proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "downregulation of proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "inhibition of proteolysis associated with antigen processing and presentation" NARROW [] +is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002628 ! regulation of proteolysis associated with antigen processing and presentation +is_a: GO:1903051 ! negative regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation +relationship: negatively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002630 +name: positive regulation of proteolysis associated with antigen processing and presentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] +synonym: "activation of proteolysis associated with antigen processing and presentation" NARROW [] +synonym: "stimulation of proteolysis associated with antigen processing and presentation" NARROW [] +synonym: "up regulation of proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "up-regulation of proteolysis associated with antigen processing and presentation" EXACT [] +synonym: "upregulation of proteolysis associated with antigen processing and presentation" EXACT [] +is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen +is_a: GO:0002628 ! regulation of proteolysis associated with antigen processing and presentation +is_a: GO:1903052 ! positive regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation +relationship: positively_regulates GO:0002496 ! proteolysis associated with antigen processing and presentation + +[Term] +id: GO:0002631 +name: regulation of granuloma formation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of granuloma formation." [GOC:add] +is_a: GO:0002676 ! regulation of chronic inflammatory response +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002432 ! granuloma formation +relationship: regulates GO:0002432 ! granuloma formation + +[Term] +id: GO:0002632 +name: negative regulation of granuloma formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation." [GOC:add] +synonym: "down regulation of granuloma formation" EXACT [] +synonym: "down-regulation of granuloma formation" EXACT [] +synonym: "downregulation of granuloma formation" EXACT [] +synonym: "inhibition of granuloma formation" NARROW [] +is_a: GO:0002631 ! regulation of granuloma formation +is_a: GO:0002677 ! negative regulation of chronic inflammatory response +is_a: GO:0002698 ! negative regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002432 ! granuloma formation +relationship: negatively_regulates GO:0002432 ! granuloma formation + +[Term] +id: GO:0002633 +name: positive regulation of granuloma formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of granuloma formation." [GOC:add] +synonym: "activation of granuloma formation" NARROW [] +synonym: "stimulation of granuloma formation" NARROW [] +synonym: "up regulation of granuloma formation" EXACT [] +synonym: "up-regulation of granuloma formation" EXACT [] +synonym: "upregulation of granuloma formation" EXACT [] +is_a: GO:0002631 ! regulation of granuloma formation +is_a: GO:0002678 ! positive regulation of chronic inflammatory response +is_a: GO:0002699 ! positive regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002432 ! granuloma formation +relationship: positively_regulates GO:0002432 ! granuloma formation + +[Term] +id: GO:0002634 +name: regulation of germinal center formation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of germinal center formation." [GOC:add] +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002467 ! germinal center formation +relationship: regulates GO:0002467 ! germinal center formation + +[Term] +id: GO:0002635 +name: negative regulation of germinal center formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation." [GOC:add] +synonym: "down regulation of germinal center formation" EXACT [] +synonym: "down-regulation of germinal center formation" EXACT [] +synonym: "downregulation of germinal center formation" EXACT [] +synonym: "inhibition of germinal center formation" NARROW [] +is_a: GO:0002634 ! regulation of germinal center formation +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002467 ! germinal center formation +relationship: negatively_regulates GO:0002467 ! germinal center formation + +[Term] +id: GO:0002636 +name: positive regulation of germinal center formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of germinal center formation." [GOC:add] +synonym: "activation of germinal center formation" NARROW [] +synonym: "stimulation of germinal center formation" NARROW [] +synonym: "up regulation of germinal center formation" EXACT [] +synonym: "up-regulation of germinal center formation" EXACT [] +synonym: "upregulation of germinal center formation" EXACT [] +is_a: GO:0002634 ! regulation of germinal center formation +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002467 ! germinal center formation +relationship: positively_regulates GO:0002467 ! germinal center formation + +[Term] +id: GO:0002637 +name: regulation of immunoglobulin production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of immunoglobulin production." [GOC:add] +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002377 ! immunoglobulin production +relationship: regulates GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0002638 +name: negative regulation of immunoglobulin production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production." [GOC:add] +synonym: "down regulation of immunoglobulin production" EXACT [] +synonym: "down-regulation of immunoglobulin production" EXACT [] +synonym: "downregulation of immunoglobulin production" EXACT [] +synonym: "inhibition of immunoglobulin production" NARROW [] +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002377 ! immunoglobulin production +relationship: negatively_regulates GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0002639 +name: positive regulation of immunoglobulin production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of immunoglobulin production." [GOC:add] +synonym: "activation of immunoglobulin production" NARROW [] +synonym: "stimulation of immunoglobulin production" NARROW [] +synonym: "up regulation of immunoglobulin production" EXACT [] +synonym: "up-regulation of immunoglobulin production" EXACT [] +synonym: "upregulation of immunoglobulin production" EXACT [] +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002377 ! immunoglobulin production +relationship: positively_regulates GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0002640 +name: regulation of immunoglobulin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of immunoglobulin biosynthesis." [GOC:add] +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002378 ! immunoglobulin biosynthetic process +relationship: regulates GO:0002378 ! immunoglobulin biosynthetic process + +[Term] +id: GO:0002641 +name: negative regulation of immunoglobulin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin biosynthesis." [GOC:add] +synonym: "down regulation of immunoglobulin biosynthetic process" EXACT [] +synonym: "down-regulation of immunoglobulin biosynthetic process" EXACT [] +synonym: "downregulation of immunoglobulin biosynthetic process" EXACT [] +synonym: "inhibition of immunoglobulin biosynthetic process" NARROW [] +is_a: GO:0002638 ! negative regulation of immunoglobulin production +is_a: GO:0002640 ! regulation of immunoglobulin biosynthetic process +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002378 ! immunoglobulin biosynthetic process +relationship: negatively_regulates GO:0002378 ! immunoglobulin biosynthetic process + +[Term] +id: GO:0002642 +name: positive regulation of immunoglobulin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of immunoglobulin biosynthesis." [GOC:add] +synonym: "activation of immunoglobulin biosynthetic process" NARROW [] +synonym: "stimulation of immunoglobulin biosynthetic process" NARROW [] +synonym: "up regulation of immunoglobulin biosynthetic process" EXACT [] +synonym: "up-regulation of immunoglobulin biosynthetic process" EXACT [] +synonym: "upregulation of immunoglobulin biosynthetic process" EXACT [] +is_a: GO:0002639 ! positive regulation of immunoglobulin production +is_a: GO:0002640 ! regulation of immunoglobulin biosynthetic process +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002378 ! immunoglobulin biosynthetic process +relationship: positively_regulates GO:0002378 ! immunoglobulin biosynthetic process + +[Term] +id: GO:0002643 +name: regulation of tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tolerance induction." [GOC:add] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002507 ! tolerance induction +relationship: regulates GO:0002507 ! tolerance induction + +[Term] +id: GO:0002644 +name: negative regulation of tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction." [GOC:add] +synonym: "down regulation of tolerance induction" EXACT [] +synonym: "down-regulation of tolerance induction" EXACT [] +synonym: "downregulation of tolerance induction" EXACT [] +synonym: "inhibition of tolerance induction" NARROW [] +is_a: GO:0002643 ! regulation of tolerance induction +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002507 ! tolerance induction +relationship: negatively_regulates GO:0002507 ! tolerance induction + +[Term] +id: GO:0002645 +name: positive regulation of tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tolerance induction." [GOC:add] +synonym: "activation of tolerance induction" NARROW [] +synonym: "stimulation of tolerance induction" NARROW [] +synonym: "up regulation of tolerance induction" EXACT [] +synonym: "up-regulation of tolerance induction" EXACT [] +synonym: "upregulation of tolerance induction" EXACT [] +is_a: GO:0002643 ! regulation of tolerance induction +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002507 ! tolerance induction +relationship: positively_regulates GO:0002507 ! tolerance induction + +[Term] +id: GO:0002646 +name: regulation of central tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of central tolerance induction." [GOC:add] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002508 ! central tolerance induction +relationship: regulates GO:0002508 ! central tolerance induction + +[Term] +id: GO:0002647 +name: negative regulation of central tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction." [GOC:add] +synonym: "down regulation of central tolerance induction" EXACT [] +synonym: "down-regulation of central tolerance induction" EXACT [] +synonym: "downregulation of central tolerance induction" EXACT [] +synonym: "inhibition of central tolerance induction" NARROW [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002646 ! regulation of central tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002508 ! central tolerance induction +relationship: negatively_regulates GO:0002508 ! central tolerance induction + +[Term] +id: GO:0002648 +name: positive regulation of central tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of central tolerance induction." [GOC:add] +synonym: "activation of central tolerance induction" NARROW [] +synonym: "stimulation of central tolerance induction" NARROW [] +synonym: "up regulation of central tolerance induction" EXACT [] +synonym: "up-regulation of central tolerance induction" EXACT [] +synonym: "upregulation of central tolerance induction" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002646 ! regulation of central tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002508 ! central tolerance induction +relationship: positively_regulates GO:0002508 ! central tolerance induction + +[Term] +id: GO:0002649 +name: regulation of tolerance induction to self antigen +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen." [GOC:add] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002513 ! tolerance induction to self antigen +relationship: regulates GO:0002513 ! tolerance induction to self antigen + +[Term] +id: GO:0002650 +name: negative regulation of tolerance induction to self antigen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen." [GOC:add] +synonym: "down regulation of tolerance induction to self antigen" EXACT [] +synonym: "down-regulation of tolerance induction to self antigen" EXACT [] +synonym: "downregulation of tolerance induction to self antigen" EXACT [] +synonym: "inhibition of tolerance induction to self antigen" NARROW [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002649 ! regulation of tolerance induction to self antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002513 ! tolerance induction to self antigen +relationship: negatively_regulates GO:0002513 ! tolerance induction to self antigen + +[Term] +id: GO:0002651 +name: positive regulation of tolerance induction to self antigen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen." [GOC:add] +synonym: "activation of tolerance induction to self antigen" NARROW [] +synonym: "stimulation of tolerance induction to self antigen" NARROW [] +synonym: "up regulation of tolerance induction to self antigen" EXACT [] +synonym: "up-regulation of tolerance induction to self antigen" EXACT [] +synonym: "upregulation of tolerance induction to self antigen" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002649 ! regulation of tolerance induction to self antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002513 ! tolerance induction to self antigen +relationship: positively_regulates GO:0002513 ! tolerance induction to self antigen + +[Term] +id: GO:0002652 +name: regulation of tolerance induction dependent upon immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response." [GOC:add] +synonym: "regulation of immune response-dependent tolerance induction" EXACT [] +is_a: GO:0002643 ! regulation of tolerance induction +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002461 ! tolerance induction dependent upon immune response +relationship: regulates GO:0002461 ! tolerance induction dependent upon immune response + +[Term] +id: GO:0002653 +name: negative regulation of tolerance induction dependent upon immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response." [GOC:add] +synonym: "down regulation of tolerance induction dependent upon immune response" EXACT [] +synonym: "down-regulation of tolerance induction dependent upon immune response" EXACT [] +synonym: "downregulation of tolerance induction dependent upon immune response" EXACT [] +synonym: "inhibition of tolerance induction dependent upon immune response" NARROW [] +synonym: "negative regulation of immune response-dependent tolerance induction" EXACT [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002652 ! regulation of tolerance induction dependent upon immune response +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002461 ! tolerance induction dependent upon immune response +relationship: negatively_regulates GO:0002461 ! tolerance induction dependent upon immune response + +[Term] +id: GO:0002654 +name: positive regulation of tolerance induction dependent upon immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response." [GOC:add] +synonym: "activation of tolerance induction dependent upon immune response" NARROW [] +synonym: "positive regulation of immune response-dependent tolerance induction" EXACT [] +synonym: "stimulation of tolerance induction dependent upon immune response" NARROW [] +synonym: "up regulation of tolerance induction dependent upon immune response" EXACT [] +synonym: "up-regulation of tolerance induction dependent upon immune response" EXACT [] +synonym: "upregulation of tolerance induction dependent upon immune response" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002652 ! regulation of tolerance induction dependent upon immune response +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002461 ! tolerance induction dependent upon immune response +relationship: positively_regulates GO:0002461 ! tolerance induction dependent upon immune response + +[Term] +id: GO:0002655 +name: regulation of tolerance induction to nonself antigen +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen." [GOC:add] +is_a: GO:0002652 ! regulation of tolerance induction dependent upon immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002462 ! tolerance induction to nonself antigen +relationship: regulates GO:0002462 ! tolerance induction to nonself antigen + +[Term] +id: GO:0002656 +name: negative regulation of tolerance induction to nonself antigen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen." [GOC:add] +synonym: "down regulation of tolerance induction to nonself antigen" EXACT [] +synonym: "down-regulation of tolerance induction to nonself antigen" EXACT [] +synonym: "downregulation of tolerance induction to nonself antigen" EXACT [] +synonym: "inhibition of tolerance induction to nonself antigen" NARROW [] +is_a: GO:0002653 ! negative regulation of tolerance induction dependent upon immune response +is_a: GO:0002655 ! regulation of tolerance induction to nonself antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002462 ! tolerance induction to nonself antigen +relationship: negatively_regulates GO:0002462 ! tolerance induction to nonself antigen + +[Term] +id: GO:0002657 +name: positive regulation of tolerance induction to nonself antigen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen." [GOC:add] +synonym: "activation of tolerance induction to nonself antigen" NARROW [] +synonym: "stimulation of tolerance induction to nonself antigen" NARROW [] +synonym: "up regulation of tolerance induction to nonself antigen" EXACT [] +synonym: "up-regulation of tolerance induction to nonself antigen" EXACT [] +synonym: "upregulation of tolerance induction to nonself antigen" EXACT [] +is_a: GO:0002654 ! positive regulation of tolerance induction dependent upon immune response +is_a: GO:0002655 ! regulation of tolerance induction to nonself antigen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002462 ! tolerance induction to nonself antigen +relationship: positively_regulates GO:0002462 ! tolerance induction to nonself antigen + +[Term] +id: GO:0002658 +name: regulation of peripheral tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of peripheral tolerance induction." [GOC:add] +is_a: GO:0002652 ! regulation of tolerance induction dependent upon immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002465 ! peripheral tolerance induction +relationship: regulates GO:0002465 ! peripheral tolerance induction + +[Term] +id: GO:0002659 +name: negative regulation of peripheral tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction." [GOC:add] +synonym: "down regulation of peripheral tolerance induction" EXACT [] +synonym: "down-regulation of peripheral tolerance induction" EXACT [] +synonym: "downregulation of peripheral tolerance induction" EXACT [] +synonym: "inhibition of peripheral tolerance induction" NARROW [] +is_a: GO:0002653 ! negative regulation of tolerance induction dependent upon immune response +is_a: GO:0002658 ! regulation of peripheral tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002465 ! peripheral tolerance induction +relationship: negatively_regulates GO:0002465 ! peripheral tolerance induction + +[Term] +id: GO:0002660 +name: positive regulation of peripheral tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction." [GOC:add] +synonym: "activation of peripheral tolerance induction" NARROW [] +synonym: "stimulation of peripheral tolerance induction" NARROW [] +synonym: "up regulation of peripheral tolerance induction" EXACT [] +synonym: "up-regulation of peripheral tolerance induction" EXACT [] +synonym: "upregulation of peripheral tolerance induction" EXACT [] +is_a: GO:0002654 ! positive regulation of tolerance induction dependent upon immune response +is_a: GO:0002658 ! regulation of peripheral tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002465 ! peripheral tolerance induction +relationship: positively_regulates GO:0002465 ! peripheral tolerance induction + +[Term] +id: GO:0002661 +name: regulation of B cell tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell tolerance induction." [GOC:add] +synonym: "regulation of B lymphocyte tolerance induction" EXACT [] +synonym: "regulation of B-cell tolerance induction" EXACT [] +synonym: "regulation of B-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002514 ! B cell tolerance induction +relationship: regulates GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002662 +name: negative regulation of B cell tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction." [GOC:add] +synonym: "down regulation of B cell tolerance induction" EXACT [] +synonym: "down-regulation of B cell tolerance induction" EXACT [] +synonym: "downregulation of B cell tolerance induction" EXACT [] +synonym: "inhibition of B cell tolerance induction" NARROW [] +synonym: "negative regulation of B lymphocyte tolerance induction" EXACT [] +synonym: "negative regulation of B-cell tolerance induction" EXACT [] +synonym: "negative regulation of B-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002661 ! regulation of B cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002514 ! B cell tolerance induction +relationship: negatively_regulates GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002663 +name: positive regulation of B cell tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction." [GOC:add] +synonym: "activation of B cell tolerance induction" NARROW [] +synonym: "positive regulation of B lymphocyte tolerance induction" EXACT [] +synonym: "positive regulation of B-cell tolerance induction" EXACT [] +synonym: "positive regulation of B-lymphocyte tolerance induction" EXACT [] +synonym: "stimulation of B cell tolerance induction" NARROW [] +synonym: "up regulation of B cell tolerance induction" EXACT [] +synonym: "up-regulation of B cell tolerance induction" EXACT [] +synonym: "upregulation of B cell tolerance induction" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002661 ! regulation of B cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002514 ! B cell tolerance induction +relationship: positively_regulates GO:0002514 ! B cell tolerance induction + +[Term] +id: GO:0002664 +name: regulation of T cell tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell tolerance induction." [GOC:add] +synonym: "regulation of T lymphocyte tolerance induction" EXACT [] +synonym: "regulation of T-cell tolerance induction" EXACT [] +synonym: "regulation of T-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002517 ! T cell tolerance induction +relationship: regulates GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002665 +name: negative regulation of T cell tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction." [GOC:add] +synonym: "down regulation of T cell tolerance induction" EXACT [] +synonym: "down-regulation of T cell tolerance induction" EXACT [] +synonym: "downregulation of T cell tolerance induction" EXACT [] +synonym: "inhibition of T cell tolerance induction" NARROW [] +synonym: "negative regulation of T lymphocyte tolerance induction" EXACT [] +synonym: "negative regulation of T-cell tolerance induction" EXACT [] +synonym: "negative regulation of T-lymphocyte tolerance induction" EXACT [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002664 ! regulation of T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002517 ! T cell tolerance induction +relationship: negatively_regulates GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002666 +name: positive regulation of T cell tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction." [GOC:add] +synonym: "activation of T cell tolerance induction" NARROW [] +synonym: "positive regulation of T lymphocyte tolerance induction" EXACT [] +synonym: "positive regulation of T-cell tolerance induction" EXACT [] +synonym: "positive regulation of T-lymphocyte tolerance induction" EXACT [] +synonym: "stimulation of T cell tolerance induction" NARROW [] +synonym: "up regulation of T cell tolerance induction" EXACT [] +synonym: "up-regulation of T cell tolerance induction" EXACT [] +synonym: "upregulation of T cell tolerance induction" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002664 ! regulation of T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002517 ! T cell tolerance induction +relationship: positively_regulates GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002667 +name: regulation of T cell anergy +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell anergy." [GOC:add] +synonym: "regulation of T lymphocyte anergy" EXACT [] +synonym: "regulation of T-cell anergy" EXACT [] +synonym: "regulation of T-lymphocyte anergy" EXACT [] +is_a: GO:0002664 ! regulation of T cell tolerance induction +is_a: GO:0002911 ! regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002870 ! T cell anergy +relationship: regulates GO:0002870 ! T cell anergy + +[Term] +id: GO:0002668 +name: negative regulation of T cell anergy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy." [GOC:add] +synonym: "down regulation of T cell anergy" EXACT [] +synonym: "down-regulation of T cell anergy" EXACT [] +synonym: "downregulation of T cell anergy" EXACT [] +synonym: "inhibition of T cell anergy" NARROW [] +synonym: "negative regulation of T lymphocyte anergy" EXACT [] +synonym: "negative regulation of T-cell anergy" EXACT [] +synonym: "negative regulation of T-lymphocyte anergy" EXACT [] +is_a: GO:0002665 ! negative regulation of T cell tolerance induction +is_a: GO:0002667 ! regulation of T cell anergy +is_a: GO:0002912 ! negative regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002870 ! T cell anergy +relationship: negatively_regulates GO:0002870 ! T cell anergy + +[Term] +id: GO:0002669 +name: positive regulation of T cell anergy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell anergy." [GOC:add] +synonym: "activation of T cell anergy" NARROW [] +synonym: "positive regulation of T lymphocyte anergy" EXACT [] +synonym: "positive regulation of T-cell anergy" EXACT [] +synonym: "positive regulation of T-lymphocyte anergy" EXACT [] +synonym: "stimulation of T cell anergy" NARROW [] +synonym: "up regulation of T cell anergy" EXACT [] +synonym: "up-regulation of T cell anergy" EXACT [] +synonym: "upregulation of T cell anergy" EXACT [] +is_a: GO:0002666 ! positive regulation of T cell tolerance induction +is_a: GO:0002667 ! regulation of T cell anergy +is_a: GO:0002913 ! positive regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002870 ! T cell anergy +relationship: positively_regulates GO:0002870 ! T cell anergy + +[Term] +id: GO:0002670 +name: regulation of B cell anergy +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell anergy." [GOC:add] +synonym: "regulation of B lymphocyte anergy" EXACT [] +synonym: "regulation of B-cell anergy" EXACT [] +synonym: "regulation of B-lymphocyte anergy" EXACT [] +is_a: GO:0002661 ! regulation of B cell tolerance induction +is_a: GO:0002911 ! regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002515 ! B cell anergy +relationship: regulates GO:0002515 ! B cell anergy + +[Term] +id: GO:0002671 +name: negative regulation of B cell anergy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy." [GOC:add] +synonym: "down regulation of B cell anergy" EXACT [] +synonym: "down-regulation of B cell anergy" EXACT [] +synonym: "downregulation of B cell anergy" EXACT [] +synonym: "inhibition of B cell anergy" NARROW [] +synonym: "negative regulation of B lymphocyte anergy" EXACT [] +synonym: "negative regulation of B-cell anergy" EXACT [] +synonym: "negative regulation of B-lymphocyte anergy" EXACT [] +is_a: GO:0002662 ! negative regulation of B cell tolerance induction +is_a: GO:0002670 ! regulation of B cell anergy +is_a: GO:0002912 ! negative regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002515 ! B cell anergy +relationship: negatively_regulates GO:0002515 ! B cell anergy + +[Term] +id: GO:0002672 +name: positive regulation of B cell anergy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell anergy." [GOC:add] +synonym: "activation of B cell anergy" NARROW [] +synonym: "positive regulation of B lymphocyte anergy" EXACT [] +synonym: "positive regulation of B-cell anergy" EXACT [] +synonym: "positive regulation of B-lymphocyte anergy" EXACT [] +synonym: "stimulation of B cell anergy" NARROW [] +synonym: "up regulation of B cell anergy" EXACT [] +synonym: "up-regulation of B cell anergy" EXACT [] +synonym: "upregulation of B cell anergy" EXACT [] +is_a: GO:0002663 ! positive regulation of B cell tolerance induction +is_a: GO:0002670 ! regulation of B cell anergy +is_a: GO:0002913 ! positive regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002515 ! B cell anergy +relationship: positively_regulates GO:0002515 ! B cell anergy + +[Term] +id: GO:0002673 +name: regulation of acute inflammatory response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an acute inflammatory response." [GOC:add] +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002526 ! acute inflammatory response +relationship: regulates GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002674 +name: negative regulation of acute inflammatory response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response." [GOC:add] +synonym: "down regulation of acute inflammatory response" EXACT [] +synonym: "down-regulation of acute inflammatory response" EXACT [] +synonym: "downregulation of acute inflammatory response" EXACT [] +synonym: "inhibition of acute inflammatory response" NARROW [] +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0050728 ! negative regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002526 ! acute inflammatory response +relationship: negatively_regulates GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002675 +name: positive regulation of acute inflammatory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response." [GOC:add] +synonym: "activation of acute inflammatory response" NARROW [] +synonym: "stimulation of acute inflammatory response" NARROW [] +synonym: "up regulation of acute inflammatory response" EXACT [] +synonym: "up-regulation of acute inflammatory response" EXACT [] +synonym: "upregulation of acute inflammatory response" EXACT [] +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0050729 ! positive regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002526 ! acute inflammatory response +relationship: positively_regulates GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0002676 +name: regulation of chronic inflammatory response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a chronic inflammatory response." [GOC:add] +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002544 ! chronic inflammatory response +relationship: regulates GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002677 +name: negative regulation of chronic inflammatory response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response." [GOC:add] +synonym: "down regulation of chronic inflammatory response" EXACT [] +synonym: "down-regulation of chronic inflammatory response" EXACT [] +synonym: "downregulation of chronic inflammatory response" EXACT [] +synonym: "inhibition of chronic inflammatory response" NARROW [] +is_a: GO:0002676 ! regulation of chronic inflammatory response +is_a: GO:0050728 ! negative regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002544 ! chronic inflammatory response +relationship: negatively_regulates GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002678 +name: positive regulation of chronic inflammatory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response." [GOC:add] +synonym: "activation of chronic inflammatory response" NARROW [] +synonym: "stimulation of chronic inflammatory response" NARROW [] +synonym: "up regulation of chronic inflammatory response" EXACT [] +synonym: "up-regulation of chronic inflammatory response" EXACT [] +synonym: "upregulation of chronic inflammatory response" EXACT [] +is_a: GO:0002676 ! regulation of chronic inflammatory response +is_a: GO:0050729 ! positive regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002544 ! chronic inflammatory response +relationship: positively_regulates GO:0002544 ! chronic inflammatory response + +[Term] +id: GO:0002679 +name: respiratory burst involved in defense response +namespace: biological_process +def: "A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:add, ISBN:0781735149, PMID:12789499] +is_a: GO:0002252 ! immune effector process +is_a: GO:0045730 ! respiratory burst +intersection_of: GO:0045730 ! respiratory burst +intersection_of: part_of GO:0006952 ! defense response +relationship: part_of GO:0006952 ! defense response + +[Term] +id: GO:0002680 +name: pro-T cell lineage commitment +namespace: biological_process +def: "The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell." [GOC:add, ISBN:0781735149] +synonym: "pro-T cell fate commitment" EXACT [] +synonym: "pro-T lymphocyte fate commitment" EXACT [] +synonym: "pro-T lymphocyte lineage commitment" EXACT [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0002572 ! pro-T cell differentiation + +[Term] +id: GO:0002681 +name: somatic recombination of T cell receptor gene segments +namespace: biological_process +def: "The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments." [GOC:add, ISBN:0781735149] +synonym: "somatic recombination of TCR gene segments" EXACT [] +is_a: GO:0002562 ! somatic diversification of immune receptors via germline recombination within a single locus +is_a: GO:0002568 ! somatic diversification of T cell receptor genes + +[Term] +id: GO:0002682 +name: regulation of immune system process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002376 ! immune system process +relationship: regulates GO:0002376 ! immune system process + +[Term] +id: GO:0002683 +name: negative regulation of immune system process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add] +synonym: "down regulation of immune system process" EXACT [] +synonym: "down-regulation of immune system process" EXACT [] +synonym: "downregulation of immune system process" EXACT [] +synonym: "inhibition of immune system process" NARROW [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002376 ! immune system process +relationship: negatively_regulates GO:0002376 ! immune system process + +[Term] +id: GO:0002684 +name: positive regulation of immune system process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] +synonym: "activation of immune system process" NARROW [] +synonym: "stimulation of immune system process" NARROW [] +synonym: "up regulation of immune system process" EXACT [] +synonym: "up-regulation of immune system process" EXACT [] +synonym: "upregulation of immune system process" EXACT [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002376 ! immune system process +relationship: positively_regulates GO:0002376 ! immune system process + +[Term] +id: GO:0002685 +name: regulation of leukocyte migration +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] +synonym: "regulation of immune cell migration" EXACT [] +synonym: "regulation of leucocyte migration" EXACT [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050900 ! leukocyte migration +relationship: regulates GO:0050900 ! leukocyte migration + +[Term] +id: GO:0002686 +name: negative regulation of leukocyte migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] +synonym: "down regulation of leukocyte migration" EXACT [] +synonym: "down-regulation of leukocyte migration" EXACT [] +synonym: "downregulation of leukocyte migration" EXACT [] +synonym: "inhibition of leukocyte migration" NARROW [] +synonym: "negative regulation of immune cell migration" EXACT [] +synonym: "negative regulation of leucocyte migration" EXACT [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0002685 ! regulation of leukocyte migration +is_a: GO:0030336 ! negative regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050900 ! leukocyte migration +relationship: negatively_regulates GO:0050900 ! leukocyte migration + +[Term] +id: GO:0002687 +name: positive regulation of leukocyte migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] +synonym: "activation of leukocyte migration" NARROW [] +synonym: "positive regulation of immune cell migration" EXACT [] +synonym: "positive regulation of leucocyte migration" EXACT [] +synonym: "stimulation of leukocyte migration" NARROW [] +synonym: "up regulation of leukocyte migration" EXACT [] +synonym: "up-regulation of leukocyte migration" EXACT [] +synonym: "upregulation of leukocyte migration" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0002685 ! regulation of leukocyte migration +is_a: GO:0030335 ! positive regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050900 ! leukocyte migration +relationship: positively_regulates GO:0050900 ! leukocyte migration + +[Term] +id: GO:0002688 +name: regulation of leukocyte chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] +synonym: "regulation of immune cell chemotaxis" EXACT [] +synonym: "regulation of leucocyte chemotaxis" EXACT [] +is_a: GO:0002685 ! regulation of leukocyte migration +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030595 ! leukocyte chemotaxis +relationship: regulates GO:0030595 ! leukocyte chemotaxis + +[Term] +id: GO:0002689 +name: negative regulation of leukocyte chemotaxis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] +synonym: "down regulation of leukocyte chemotaxis" EXACT [] +synonym: "down-regulation of leukocyte chemotaxis" EXACT [] +synonym: "downregulation of leukocyte chemotaxis" EXACT [] +synonym: "inhibition of leukocyte chemotaxis" NARROW [] +synonym: "negative regulation of immune cell chemotaxis" EXACT [] +synonym: "negative regulation of leucocyte chemotaxis" EXACT [] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +is_a: GO:0050922 ! negative regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030595 ! leukocyte chemotaxis +relationship: negatively_regulates GO:0030595 ! leukocyte chemotaxis + +[Term] +id: GO:0002690 +name: positive regulation of leukocyte chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] +synonym: "activation of leukocyte chemotaxis" NARROW [] +synonym: "positive regulation of immune cell chemotaxis" EXACT [] +synonym: "positive regulation of leucocyte chemotaxis" EXACT [] +synonym: "stimulation of leukocyte chemotaxis" NARROW [] +synonym: "up regulation of leukocyte chemotaxis" EXACT [] +synonym: "up-regulation of leukocyte chemotaxis" EXACT [] +synonym: "upregulation of leukocyte chemotaxis" EXACT [] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +is_a: GO:0050921 ! positive regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030595 ! leukocyte chemotaxis +relationship: positively_regulates GO:0030595 ! leukocyte chemotaxis + +[Term] +id: GO:0002691 +name: regulation of cellular extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cellular extravasation." [GOC:add] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045123 ! cellular extravasation +relationship: regulates GO:0045123 ! cellular extravasation + +[Term] +id: GO:0002692 +name: negative regulation of cellular extravasation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation." [GOC:add] +synonym: "down regulation of cellular extravasation" EXACT [] +synonym: "down-regulation of cellular extravasation" EXACT [] +synonym: "downregulation of cellular extravasation" EXACT [] +synonym: "inhibition of cellular extravasation" NARROW [] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:0002691 ! regulation of cellular extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045123 ! cellular extravasation +relationship: negatively_regulates GO:0045123 ! cellular extravasation + +[Term] +id: GO:0002693 +name: positive regulation of cellular extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cellular extravasation." [GOC:add] +synonym: "activation of cellular extravasation" NARROW [] +synonym: "stimulation of cellular extravasation" NARROW [] +synonym: "up regulation of cellular extravasation" EXACT [] +synonym: "up-regulation of cellular extravasation" EXACT [] +synonym: "upregulation of cellular extravasation" EXACT [] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:0002691 ! regulation of cellular extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045123 ! cellular extravasation +relationship: positively_regulates GO:0045123 ! cellular extravasation + +[Term] +id: GO:0002694 +name: regulation of leukocyte activation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] +synonym: "regulation of immune cell activation" EXACT [] +synonym: "regulation of leucocyte activation" EXACT [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045321 ! leukocyte activation +relationship: regulates GO:0045321 ! leukocyte activation + +[Term] +id: GO:0002695 +name: negative regulation of leukocyte activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] +synonym: "down regulation of leukocyte activation" EXACT [] +synonym: "down-regulation of leukocyte activation" EXACT [] +synonym: "downregulation of leukocyte activation" EXACT [] +synonym: "inhibition of leukocyte activation" NARROW [] +synonym: "negative regulation of immune cell activation" EXACT [] +synonym: "negative regulation of leucocyte activation" EXACT [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0002694 ! regulation of leukocyte activation +is_a: GO:0050866 ! negative regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045321 ! leukocyte activation +relationship: negatively_regulates GO:0045321 ! leukocyte activation + +[Term] +id: GO:0002696 +name: positive regulation of leukocyte activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] +synonym: "activation of leukocyte activation" NARROW [] +synonym: "positive regulation of immune cell activation" EXACT [] +synonym: "positive regulation of leucocyte activation" EXACT [] +synonym: "stimulation of leukocyte activation" NARROW [] +synonym: "up regulation of leukocyte activation" EXACT [] +synonym: "up-regulation of leukocyte activation" EXACT [] +synonym: "upregulation of leukocyte activation" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0002694 ! regulation of leukocyte activation +is_a: GO:0050867 ! positive regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045321 ! leukocyte activation +relationship: positively_regulates GO:0045321 ! leukocyte activation + +[Term] +id: GO:0002697 +name: regulation of immune effector process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] +is_a: GO:0002682 ! regulation of immune system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002252 ! immune effector process +relationship: regulates GO:0002252 ! immune effector process + +[Term] +id: GO:0002698 +name: negative regulation of immune effector process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add] +synonym: "down regulation of immune effector process" EXACT [] +synonym: "down-regulation of immune effector process" EXACT [] +synonym: "downregulation of immune effector process" EXACT [] +synonym: "inhibition of immune effector process" NARROW [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002252 ! immune effector process +relationship: negatively_regulates GO:0002252 ! immune effector process + +[Term] +id: GO:0002699 +name: positive regulation of immune effector process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add] +synonym: "activation of immune effector process" NARROW [] +synonym: "stimulation of immune effector process" NARROW [] +synonym: "up regulation of immune effector process" EXACT [] +synonym: "up-regulation of immune effector process" EXACT [] +synonym: "upregulation of immune effector process" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002252 ! immune effector process +relationship: positively_regulates GO:0002252 ! immune effector process + +[Term] +id: GO:0002700 +name: regulation of production of molecular mediator of immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002440 ! production of molecular mediator of immune response +relationship: regulates GO:0002440 ! production of molecular mediator of immune response + +[Term] +id: GO:0002701 +name: negative regulation of production of molecular mediator of immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] +synonym: "down regulation of production of molecular mediator of immune response" EXACT [] +synonym: "down-regulation of production of molecular mediator of immune response" EXACT [] +synonym: "downregulation of production of molecular mediator of immune response" EXACT [] +synonym: "inhibition of production of molecular mediator of immune response" NARROW [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002440 ! production of molecular mediator of immune response +relationship: negatively_regulates GO:0002440 ! production of molecular mediator of immune response + +[Term] +id: GO:0002702 +name: positive regulation of production of molecular mediator of immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] +synonym: "activation of production of molecular mediator of immune response" NARROW [] +synonym: "stimulation of production of molecular mediator of immune response" NARROW [] +synonym: "up regulation of production of molecular mediator of immune response" EXACT [] +synonym: "up-regulation of production of molecular mediator of immune response" EXACT [] +synonym: "upregulation of production of molecular mediator of immune response" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002440 ! production of molecular mediator of immune response +relationship: positively_regulates GO:0002440 ! production of molecular mediator of immune response + +[Term] +id: GO:0002703 +name: regulation of leukocyte mediated immunity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] +synonym: "regulation of immune cell mediated immunity" EXACT [] +synonym: "regulation of leucocyte mediated immunity" EXACT [] +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002443 ! leukocyte mediated immunity +relationship: regulates GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002704 +name: negative regulation of leukocyte mediated immunity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] +synonym: "down regulation of leukocyte mediated immunity" EXACT [] +synonym: "down-regulation of leukocyte mediated immunity" EXACT [] +synonym: "downregulation of leukocyte mediated immunity" EXACT [] +synonym: "inhibition of leukocyte mediated immunity" NARROW [] +synonym: "negative regulation of immune cell mediated immunity" EXACT [] +synonym: "negative regulation of leucocyte mediated immunity" EXACT [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002443 ! leukocyte mediated immunity +relationship: negatively_regulates GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002705 +name: positive regulation of leukocyte mediated immunity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] +synonym: "activation of leukocyte mediated immunity" NARROW [] +synonym: "positive regulation of immune cell mediated immunity" EXACT [] +synonym: "positive regulation of leucocyte mediated immunity" EXACT [] +synonym: "stimulation of leukocyte mediated immunity" NARROW [] +synonym: "up regulation of leukocyte mediated immunity" EXACT [] +synonym: "up-regulation of leukocyte mediated immunity" EXACT [] +synonym: "upregulation of leukocyte mediated immunity" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002443 ! leukocyte mediated immunity +relationship: positively_regulates GO:0002443 ! leukocyte mediated immunity + +[Term] +id: GO:0002706 +name: regulation of lymphocyte mediated immunity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002449 ! lymphocyte mediated immunity +relationship: regulates GO:0002449 ! lymphocyte mediated immunity + +[Term] +id: GO:0002707 +name: negative regulation of lymphocyte mediated immunity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] +synonym: "down regulation of lymphocyte mediated immunity" EXACT [] +synonym: "down-regulation of lymphocyte mediated immunity" EXACT [] +synonym: "downregulation of lymphocyte mediated immunity" EXACT [] +synonym: "inhibition of lymphocyte mediated immunity" NARROW [] +is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity +is_a: GO:0002706 ! regulation of lymphocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002449 ! lymphocyte mediated immunity +relationship: negatively_regulates GO:0002449 ! lymphocyte mediated immunity + +[Term] +id: GO:0002708 +name: positive regulation of lymphocyte mediated immunity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] +synonym: "activation of lymphocyte mediated immunity" NARROW [] +synonym: "stimulation of lymphocyte mediated immunity" NARROW [] +synonym: "up regulation of lymphocyte mediated immunity" EXACT [] +synonym: "up-regulation of lymphocyte mediated immunity" EXACT [] +synonym: "upregulation of lymphocyte mediated immunity" EXACT [] +is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity +is_a: GO:0002706 ! regulation of lymphocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002449 ! lymphocyte mediated immunity +relationship: positively_regulates GO:0002449 ! lymphocyte mediated immunity + +[Term] +id: GO:0002709 +name: regulation of T cell mediated immunity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add] +synonym: "regulation of T lymphocyte mediated immunity" EXACT [] +synonym: "regulation of T-cell mediated immunity" EXACT [] +synonym: "regulation of T-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002706 ! regulation of lymphocyte mediated immunity +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002456 ! T cell mediated immunity +relationship: regulates GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002710 +name: negative regulation of T cell mediated immunity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add] +synonym: "down regulation of T cell mediated immunity" EXACT [] +synonym: "down-regulation of T cell mediated immunity" EXACT [] +synonym: "downregulation of T cell mediated immunity" EXACT [] +synonym: "inhibition of T cell mediated immunity" NARROW [] +synonym: "negative regulation of T lymphocyte mediated immunity" EXACT [] +synonym: "negative regulation of T-cell mediated immunity" EXACT [] +synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity +is_a: GO:0002709 ! regulation of T cell mediated immunity +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002456 ! T cell mediated immunity +relationship: negatively_regulates GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002711 +name: positive regulation of T cell mediated immunity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add] +synonym: "activation of T cell mediated immunity" NARROW [] +synonym: "positive regulation of T lymphocyte mediated immunity" EXACT [] +synonym: "positive regulation of T-cell mediated immunity" EXACT [] +synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT [] +synonym: "stimulation of T cell mediated immunity" NARROW [] +synonym: "up regulation of T cell mediated immunity" EXACT [] +synonym: "up-regulation of T cell mediated immunity" EXACT [] +synonym: "upregulation of T cell mediated immunity" EXACT [] +is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity +is_a: GO:0002709 ! regulation of T cell mediated immunity +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002456 ! T cell mediated immunity +relationship: positively_regulates GO:0002456 ! T cell mediated immunity + +[Term] +id: GO:0002712 +name: regulation of B cell mediated immunity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell mediated immunity." [GOC:add] +synonym: "regulation of B lymphocyte mediated immunity" EXACT [] +synonym: "regulation of B-cell mediated immunity" EXACT [] +synonym: "regulation of B-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002706 ! regulation of lymphocyte mediated immunity +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019724 ! B cell mediated immunity +relationship: regulates GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002713 +name: negative regulation of B cell mediated immunity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity." [GOC:add] +synonym: "down regulation of B cell mediated immunity" EXACT [] +synonym: "down-regulation of B cell mediated immunity" EXACT [] +synonym: "downregulation of B cell mediated immunity" EXACT [] +synonym: "inhibition of B cell mediated immunity" NARROW [] +synonym: "negative regulation of B lymphocyte mediated immunity" EXACT [] +synonym: "negative regulation of B-cell mediated immunity" EXACT [] +synonym: "negative regulation of B-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity +is_a: GO:0002712 ! regulation of B cell mediated immunity +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019724 ! B cell mediated immunity +relationship: negatively_regulates GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002714 +name: positive regulation of B cell mediated immunity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity." [GOC:add] +synonym: "activation of B cell mediated immunity" NARROW [] +synonym: "positive regulation of B lymphocyte mediated immunity" EXACT [] +synonym: "positive regulation of B-cell mediated immunity" EXACT [] +synonym: "positive regulation of B-lymphocyte mediated immunity" EXACT [] +synonym: "stimulation of B cell mediated immunity" NARROW [] +synonym: "up regulation of B cell mediated immunity" EXACT [] +synonym: "up-regulation of B cell mediated immunity" EXACT [] +synonym: "upregulation of B cell mediated immunity" EXACT [] +is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity +is_a: GO:0002712 ! regulation of B cell mediated immunity +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019724 ! B cell mediated immunity +relationship: positively_regulates GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0002715 +name: regulation of natural killer cell mediated immunity +namespace: biological_process +alt_id: GO:0045845 +def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity." [GOC:add] +synonym: "regulation of natural killer cell activity" RELATED [] +synonym: "regulation of NK cell mediated immunity" EXACT [] +is_a: GO:0002706 ! regulation of lymphocyte mediated immunity +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002228 ! natural killer cell mediated immunity +relationship: regulates GO:0002228 ! natural killer cell mediated immunity + +[Term] +id: GO:0002716 +name: negative regulation of natural killer cell mediated immunity +namespace: biological_process +alt_id: GO:0030102 +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity." [GOC:add] +synonym: "down regulation of natural killer cell mediated immunity" EXACT [] +synonym: "down-regulation of natural killer cell mediated immunity" EXACT [] +synonym: "downregulation of natural killer cell mediated immunity" EXACT [] +synonym: "inhibition of natural killer cell mediated immunity" NARROW [] +synonym: "negative regulation of natural killer cell activity" RELATED [] +synonym: "negative regulation of NK cell activity" RELATED [] +synonym: "negative regulation of NK cell mediated immunity" EXACT [] +is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity +is_a: GO:0002715 ! regulation of natural killer cell mediated immunity +is_a: GO:0045824 ! negative regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002228 ! natural killer cell mediated immunity +relationship: negatively_regulates GO:0002228 ! natural killer cell mediated immunity + +[Term] +id: GO:0002717 +name: positive regulation of natural killer cell mediated immunity +namespace: biological_process +alt_id: GO:0045846 +def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity." [GOC:add] +synonym: "activation of natural killer cell mediated immunity" NARROW [] +synonym: "positive regulation of natural killer cell activity" RELATED [] +synonym: "positive regulation of NK cell activity" RELATED [] +synonym: "positive regulation of NK cell mediated immunity" EXACT [] +synonym: "stimulation of natural killer cell mediated immunity" NARROW [] +synonym: "up regulation of natural killer cell mediated immunity" EXACT [] +synonym: "up-regulation of natural killer cell mediated immunity" EXACT [] +synonym: "upregulation of natural killer cell mediated immunity" EXACT [] +is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity +is_a: GO:0002715 ! regulation of natural killer cell mediated immunity +is_a: GO:0045089 ! positive regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002228 ! natural killer cell mediated immunity +relationship: positively_regulates GO:0002228 ! natural killer cell mediated immunity + +[Term] +id: GO:0002718 +name: regulation of cytokine production involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] +synonym: "regulation of cytokine production during immune response" RELATED [GOC:dph] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002367 ! cytokine production involved in immune response +relationship: regulates GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002719 +name: negative regulation of cytokine production involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add] +synonym: "down regulation of cytokine production during immune response" RELATED [] +synonym: "down-regulation of cytokine production during immune response" EXACT [] +synonym: "downregulation of cytokine production during immune response" RELATED [] +synonym: "inhibition of cytokine production during immune response" RELATED [] +synonym: "negative regulation of cytokine production during immune response" RELATED [GOC:dph] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002367 ! cytokine production involved in immune response +relationship: negatively_regulates GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002720 +name: positive regulation of cytokine production involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] +synonym: "activation of cytokine production during immune response" NARROW [] +synonym: "positive regulation of cytokine production during immune response" RELATED [GOC:dph] +synonym: "stimulation of cytokine production during immune response" NARROW [] +synonym: "up regulation of cytokine production during immune response" RELATED [] +synonym: "up-regulation of cytokine production during immune response" RELATED [] +synonym: "upregulation of cytokine production during immune response" RELATED [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002367 ! cytokine production involved in immune response +relationship: positively_regulates GO:0002367 ! cytokine production involved in immune response + +[Term] +id: GO:0002721 +name: regulation of B cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell cytokine production." [GOC:add] +synonym: "regulation of B lymphocyte cytokine production" EXACT [] +synonym: "regulation of B-cell cytokine production" EXACT [] +synonym: "regulation of B-lymphocyte cytokine production" EXACT [] +is_a: GO:0002712 ! regulation of B cell mediated immunity +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002368 ! B cell cytokine production +relationship: regulates GO:0002368 ! B cell cytokine production + +[Term] +id: GO:0002722 +name: negative regulation of B cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production." [GOC:add] +synonym: "down regulation of B cell cytokine production" EXACT [] +synonym: "down-regulation of B cell cytokine production" EXACT [] +synonym: "downregulation of B cell cytokine production" EXACT [] +synonym: "inhibition of B cell cytokine production" NARROW [] +synonym: "negative regulation of B lymphocyte cytokine production" EXACT [] +synonym: "negative regulation of B-cell cytokine production" EXACT [] +synonym: "negative regulation of B-lymphocyte cytokine production" EXACT [] +is_a: GO:0002713 ! negative regulation of B cell mediated immunity +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002721 ! regulation of B cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002368 ! B cell cytokine production +relationship: negatively_regulates GO:0002368 ! B cell cytokine production + +[Term] +id: GO:0002723 +name: positive regulation of B cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell cytokine production." [GOC:add] +synonym: "activation of B cell cytokine production" NARROW [] +synonym: "positive regulation of B lymphocyte cytokine production" EXACT [] +synonym: "positive regulation of B-cell cytokine production" EXACT [] +synonym: "positive regulation of B-lymphocyte cytokine production" EXACT [] +synonym: "stimulation of B cell cytokine production" NARROW [] +synonym: "up regulation of B cell cytokine production" EXACT [] +synonym: "up-regulation of B cell cytokine production" EXACT [] +synonym: "upregulation of B cell cytokine production" EXACT [] +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002721 ! regulation of B cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002368 ! B cell cytokine production +relationship: positively_regulates GO:0002368 ! B cell cytokine production + +[Term] +id: GO:0002724 +name: regulation of T cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add] +synonym: "regulation of T lymphocyte cytokine production" EXACT [] +synonym: "regulation of T-cell cytokine production" EXACT [] +synonym: "regulation of T-lymphocyte cytokine production" EXACT [] +is_a: GO:0002709 ! regulation of T cell mediated immunity +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002369 ! T cell cytokine production +relationship: regulates GO:0002369 ! T cell cytokine production + +[Term] +id: GO:0002725 +name: negative regulation of T cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add] +synonym: "down regulation of T cell cytokine production" EXACT [] +synonym: "down-regulation of T cell cytokine production" EXACT [] +synonym: "downregulation of T cell cytokine production" EXACT [] +synonym: "inhibition of T cell cytokine production" NARROW [] +synonym: "negative regulation of T lymphocyte cytokine production" EXACT [] +synonym: "negative regulation of T-cell cytokine production" EXACT [] +synonym: "negative regulation of T-lymphocyte cytokine production" EXACT [] +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002724 ! regulation of T cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002369 ! T cell cytokine production +relationship: negatively_regulates GO:0002369 ! T cell cytokine production + +[Term] +id: GO:0002726 +name: positive regulation of T cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add] +synonym: "activation of T cell cytokine production" NARROW [] +synonym: "positive regulation of T lymphocyte cytokine production" EXACT [] +synonym: "positive regulation of T-cell cytokine production" EXACT [] +synonym: "positive regulation of T-lymphocyte cytokine production" EXACT [] +synonym: "stimulation of T cell cytokine production" NARROW [] +synonym: "up regulation of T cell cytokine production" EXACT [] +synonym: "up-regulation of T cell cytokine production" EXACT [] +synonym: "upregulation of T cell cytokine production" EXACT [] +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002724 ! regulation of T cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002369 ! T cell cytokine production +relationship: positively_regulates GO:0002369 ! T cell cytokine production + +[Term] +id: GO:0002727 +name: regulation of natural killer cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production." [GOC:add] +synonym: "regulation of NK cell cytokine production" EXACT [] +is_a: GO:0002715 ! regulation of natural killer cell mediated immunity +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002370 ! natural killer cell cytokine production +relationship: regulates GO:0002370 ! natural killer cell cytokine production + +[Term] +id: GO:0002728 +name: negative regulation of natural killer cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production." [GOC:add] +synonym: "down regulation of natural killer cell cytokine production" EXACT [] +synonym: "down-regulation of natural killer cell cytokine production" EXACT [] +synonym: "downregulation of natural killer cell cytokine production" EXACT [] +synonym: "inhibition of natural killer cell cytokine production" NARROW [] +synonym: "negative regulation of NK cell cytokine production" EXACT [] +is_a: GO:0002716 ! negative regulation of natural killer cell mediated immunity +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002727 ! regulation of natural killer cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002370 ! natural killer cell cytokine production +relationship: negatively_regulates GO:0002370 ! natural killer cell cytokine production + +[Term] +id: GO:0002729 +name: positive regulation of natural killer cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production." [GOC:add] +synonym: "activation of natural killer cell cytokine production" NARROW [] +synonym: "positive regulation of NK cell cytokine production" EXACT [] +synonym: "stimulation of natural killer cell cytokine production" NARROW [] +synonym: "up regulation of natural killer cell cytokine production" EXACT [] +synonym: "up-regulation of natural killer cell cytokine production" EXACT [] +synonym: "upregulation of natural killer cell cytokine production" EXACT [] +is_a: GO:0002717 ! positive regulation of natural killer cell mediated immunity +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002727 ! regulation of natural killer cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002370 ! natural killer cell cytokine production +relationship: positively_regulates GO:0002370 ! natural killer cell cytokine production + +[Term] +id: GO:0002730 +name: regulation of dendritic cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002371 ! dendritic cell cytokine production +relationship: regulates GO:0002371 ! dendritic cell cytokine production + +[Term] +id: GO:0002731 +name: negative regulation of dendritic cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] +synonym: "down regulation of dendritic cell cytokine production" EXACT [] +synonym: "down-regulation of dendritic cell cytokine production" EXACT [] +synonym: "downregulation of dendritic cell cytokine production" EXACT [] +synonym: "inhibition of dendritic cell cytokine production" NARROW [] +is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002730 ! regulation of dendritic cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002371 ! dendritic cell cytokine production +relationship: negatively_regulates GO:0002371 ! dendritic cell cytokine production + +[Term] +id: GO:0002732 +name: positive regulation of dendritic cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] +synonym: "activation of dendritic cell cytokine production" NARROW [] +synonym: "stimulation of dendritic cell cytokine production" NARROW [] +synonym: "up regulation of dendritic cell cytokine production" EXACT [] +synonym: "up-regulation of dendritic cell cytokine production" EXACT [] +synonym: "upregulation of dendritic cell cytokine production" EXACT [] +is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002730 ! regulation of dendritic cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002371 ! dendritic cell cytokine production +relationship: positively_regulates GO:0002371 ! dendritic cell cytokine production + +[Term] +id: GO:0002733 +name: regulation of myeloid dendritic cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production." [GOC:add] +is_a: GO:0002730 ! regulation of dendritic cell cytokine production +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002372 ! myeloid dendritic cell cytokine production +relationship: regulates GO:0002372 ! myeloid dendritic cell cytokine production + +[Term] +id: GO:0002734 +name: negative regulation of myeloid dendritic cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production." [GOC:add] +synonym: "down regulation of myeloid dendritic cell cytokine production" EXACT [] +synonym: "down-regulation of myeloid dendritic cell cytokine production" EXACT [] +synonym: "downregulation of myeloid dendritic cell cytokine production" EXACT [] +synonym: "inhibition of myeloid dendritic cell cytokine production" NARROW [] +is_a: GO:0002731 ! negative regulation of dendritic cell cytokine production +is_a: GO:0002733 ! regulation of myeloid dendritic cell cytokine production +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002372 ! myeloid dendritic cell cytokine production +relationship: negatively_regulates GO:0002372 ! myeloid dendritic cell cytokine production + +[Term] +id: GO:0002735 +name: positive regulation of myeloid dendritic cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production." [GOC:add] +synonym: "activation of myeloid dendritic cell cytokine production" NARROW [] +synonym: "stimulation of myeloid dendritic cell cytokine production" NARROW [] +synonym: "up regulation of myeloid dendritic cell cytokine production" EXACT [] +synonym: "up-regulation of myeloid dendritic cell cytokine production" EXACT [] +synonym: "upregulation of myeloid dendritic cell cytokine production" EXACT [] +is_a: GO:0002732 ! positive regulation of dendritic cell cytokine production +is_a: GO:0002733 ! regulation of myeloid dendritic cell cytokine production +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0061081 ! positive regulation of myeloid leukocyte cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002372 ! myeloid dendritic cell cytokine production +relationship: positively_regulates GO:0002372 ! myeloid dendritic cell cytokine production + +[Term] +id: GO:0002736 +name: regulation of plasmacytoid dendritic cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production." [GOC:add] +is_a: GO:0002730 ! regulation of dendritic cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production +relationship: regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production + +[Term] +id: GO:0002737 +name: negative regulation of plasmacytoid dendritic cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production." [GOC:add] +synonym: "down regulation of plasmacytoid dendritic cell cytokine production" EXACT [] +synonym: "down-regulation of plasmacytoid dendritic cell cytokine production" EXACT [] +synonym: "downregulation of plasmacytoid dendritic cell cytokine production" EXACT [] +synonym: "inhibition of plasmacytoid dendritic cell cytokine production" NARROW [] +is_a: GO:0002731 ! negative regulation of dendritic cell cytokine production +is_a: GO:0002736 ! regulation of plasmacytoid dendritic cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production +relationship: negatively_regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production + +[Term] +id: GO:0002738 +name: positive regulation of plasmacytoid dendritic cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production." [GOC:add] +synonym: "activation of plasmacytoid dendritic cell cytokine production" NARROW [] +synonym: "stimulation of plasmacytoid dendritic cell cytokine production" NARROW [] +synonym: "up regulation of plasmacytoid dendritic cell cytokine production" EXACT [] +synonym: "up-regulation of plasmacytoid dendritic cell cytokine production" EXACT [] +synonym: "upregulation of plasmacytoid dendritic cell cytokine production" EXACT [] +is_a: GO:0002732 ! positive regulation of dendritic cell cytokine production +is_a: GO:0002736 ! regulation of plasmacytoid dendritic cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production +relationship: positively_regulates GO:0002373 ! plasmacytoid dendritic cell cytokine production + +[Term] +id: GO:0002739 +name: regulation of cytokine secretion involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cytokine secretion contributing to an immune response." [GOC:add] +synonym: "regulation of cytokine secretion during immune response" RELATED [GOC:dph] +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002374 ! cytokine secretion involved in immune response +relationship: regulates GO:0002374 ! cytokine secretion involved in immune response + +[Term] +id: GO:0002740 +name: negative regulation of cytokine secretion involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion contributing to an immune response." [GOC:add] +synonym: "down regulation of cytokine secretion during immune response" RELATED [] +synonym: "down-regulation of cytokine secretion during immune response" RELATED [] +synonym: "downregulation of cytokine secretion during immune response" RELATED [] +synonym: "inhibition of cytokine secretion during immune response" NARROW [] +synonym: "negative regulation of cytokine secretion during immune response" RELATED [GOC:dph] +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002739 ! regulation of cytokine secretion involved in immune response +is_a: GO:0050710 ! negative regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002374 ! cytokine secretion involved in immune response +relationship: negatively_regulates GO:0002374 ! cytokine secretion involved in immune response + +[Term] +id: GO:0002741 +name: positive regulation of cytokine secretion involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cytokine secretion contributing to an immune response." [GOC:add] +synonym: "activation of cytokine secretion during immune response" NARROW [] +synonym: "positive regulation of cytokine secretion during immune response" RELATED [GOC:dph] +synonym: "stimulation of cytokine secretion during immune response" NARROW [] +synonym: "up regulation of cytokine secretion during immune response" RELATED [] +synonym: "up-regulation of cytokine secretion during immune response" RELATED [] +synonym: "upregulation of cytokine secretion during immune response" RELATED [] +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002739 ! regulation of cytokine secretion involved in immune response +is_a: GO:0050715 ! positive regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002374 ! cytokine secretion involved in immune response +relationship: positively_regulates GO:0002374 ! cytokine secretion involved in immune response + +[Term] +id: GO:0002742 +name: regulation of cytokine biosynthetic process involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cytokine biosynthesis that contributes to an immune response." [GOC:add] +synonym: "regulation of cytokine biosynthetic process during immune response" RELATED [GOC:dph] +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002375 ! cytokine biosynthetic process involved in immune response +relationship: regulates GO:0002375 ! cytokine biosynthetic process involved in immune response + +[Term] +id: GO:0002743 +name: negative regulation of cytokine biosynthetic process involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine biosynthesis contributing to an immune response." [GOC:add] +synonym: "down regulation of cytokine biosynthetic process during immune response" RELATED [] +synonym: "down-regulation of cytokine biosynthetic process during immune response" RELATED [] +synonym: "downregulation of cytokine biosynthetic process during immune response" RELATED [] +synonym: "inhibition of cytokine biosynthetic process during immune response" NARROW [] +synonym: "negative regulation of cytokine biosynthetic process during immune response" RELATED [GOC:dph] +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0002742 ! regulation of cytokine biosynthetic process involved in immune response +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002375 ! cytokine biosynthetic process involved in immune response +relationship: negatively_regulates GO:0002375 ! cytokine biosynthetic process involved in immune response + +[Term] +id: GO:0002744 +name: positive regulation of cytokine biosynthetic process involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cytokine biosynthesis contributing to an immune response." [GOC:add] +synonym: "activation of cytokine biosynthetic process during immune response" NARROW [] +synonym: "positive regulation of cytokine biosynthetic process during immune response" RELATED [GOC:dph] +synonym: "stimulation of cytokine biosynthetic process during immune response" NARROW [] +synonym: "up regulation of cytokine biosynthetic process during immune response" RELATED [] +synonym: "up-regulation of cytokine biosynthetic process during immune response" RELATED [] +synonym: "upregulation of cytokine biosynthetic process during immune response" RELATED [] +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +is_a: GO:0002742 ! regulation of cytokine biosynthetic process involved in immune response +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002375 ! cytokine biosynthetic process involved in immune response +relationship: positively_regulates GO:0002375 ! cytokine biosynthetic process involved in immune response + +[Term] +id: GO:0002745 +name: antigen processing and presentation initiated by receptor mediated uptake of antigen +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor." [GOC:add, ISBN:0781735149] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002746 +name: antigen processing and presentation following pinocytosis +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis." [GOC:add, ISBN:0781735149] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002747 +name: antigen processing and presentation following phagocytosis +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis." [GOC:add, ISBN:0781735149] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0002748 +name: antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR)." [GOC:add, ISBN:0781735149] +synonym: "antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen" EXACT [] +synonym: "antigen processing and presentation initiated by PRR mediated uptake of antigen" EXACT [] +is_a: GO:0002745 ! antigen processing and presentation initiated by receptor mediated uptake of antigen + +[Term] +id: GO:0002749 +name: antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen +namespace: biological_process +def: "Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR)." [GOC:add, ISBN:0781735149, PMID:15596122] +synonym: "antigen processing and presentation initiated by TLR mediated phagocytosis of antigen" EXACT [] +is_a: GO:0002747 ! antigen processing and presentation following phagocytosis +is_a: GO:0002748 ! antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen + +[Term] +id: GO:0002750 +name: antigen processing and presentation following macropinocytosis +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis." [GOC:add, PMID:16556257] +is_a: GO:0002746 ! antigen processing and presentation following pinocytosis + +[Term] +id: GO:0002751 +name: antigen processing and presentation following receptor mediated endocytosis +namespace: biological_process +def: "Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis." [GOC:add, ISBN:0781735149] +is_a: GO:0002745 ! antigen processing and presentation initiated by receptor mediated uptake of antigen + +[Term] +id: GO:0002752 +name: cell surface pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species." [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967] +synonym: "cell surface PAMP receptor signaling pathway" EXACT [] +synonym: "cell surface pathogen receptor signaling pathway" EXACT [] +synonym: "cell surface pattern recognition receptor signalling pathway" EXACT [] +synonym: "cell surface PRR signaling pathway" EXACT [] +is_a: GO:0002220 ! innate immune response activating cell surface receptor signaling pathway +is_a: GO:0002221 ! pattern recognition receptor signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18588 xsd:anyURI + +[Term] +id: GO:0002753 +name: cytoplasmic pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species." [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967] +synonym: "cytoplasmic PAMP receptor signaling pathway" EXACT [] +synonym: "cytoplasmic pathogen receptor signaling pathway" EXACT [] +synonym: "cytoplasmic pattern recognition receptor signalling pathway" EXACT [] +synonym: "cytoplasmic PRR signaling pathway" EXACT [] +is_a: GO:0002221 ! pattern recognition receptor signaling pathway +is_a: GO:0030522 ! intracellular receptor signaling pathway +is_a: GO:0035556 ! intracellular signal transduction +intersection_of: GO:0002221 ! pattern recognition receptor signaling pathway +intersection_of: occurs_in GO:0005737 ! cytoplasm +relationship: occurs_in GO:0005737 ! cytoplasm +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18588 xsd:anyURI + +[Term] +id: GO:0002754 +name: intracellular endosomal pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species." [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967] +synonym: "intracellular vesicle PAMP receptor signaling pathway" RELATED [] +synonym: "intracellular vesicle pathogen receptor signaling pathway" RELATED [] +synonym: "intracellular vesicle pattern recognition receptor signaling pathway" RELATED [] +synonym: "intracellular vesicle pattern recognition receptor signalling pathway" RELATED [] +synonym: "intracellular vesicle PRR signaling pathway" RELATED [] +is_a: GO:0002221 ! pattern recognition receptor signaling pathway +is_a: GO:0030522 ! intracellular receptor signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18679 xsd:anyURI + +[Term] +id: GO:0002755 +name: MyD88-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] +synonym: "MyD88-dependent TLR signaling pathway" EXACT [] +synonym: "MyD88-dependent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0002756 +name: MyD88-independent toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] +synonym: "MyD88-independent TLR signaling pathway" EXACT [] +synonym: "MyD88-independent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0002757 +name: immune response-activating signal transduction +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response." [GOC:add] +is_a: GO:0002253 ! activation of immune response +is_a: GO:0002764 ! immune response-regulating signaling pathway + +[Term] +id: GO:0002758 +name: innate immune response-activating signal transduction +namespace: biological_process +alt_id: GO:0010204 +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response." [GO_REF:0000022, GOC:add] +synonym: "defence response signaling pathway, resistance gene-independent" RELATED [] +synonym: "defence response signalling pathway, resistance gene-independent" RELATED [] +synonym: "defense response signaling pathway, resistance gene-independent" RELATED [] +is_a: GO:0002218 ! activation of innate immune response +is_a: GO:0002757 ! immune response-activating signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18587 xsd:anyURI + +[Term] +id: GO:0002759 +name: regulation of antimicrobial humoral response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response." [GOC:add] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0002920 ! regulation of humoral immune response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019730 ! antimicrobial humoral response +relationship: regulates GO:0019730 ! antimicrobial humoral response + +[Term] +id: GO:0002760 +name: positive regulation of antimicrobial humoral response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response." [GOC:add] +synonym: "activation of antimicrobial humoral response" NARROW [] +synonym: "stimulation of antimicrobial humoral response" NARROW [] +synonym: "up regulation of antimicrobial humoral response" EXACT [] +synonym: "up-regulation of antimicrobial humoral response" EXACT [] +synonym: "upregulation of antimicrobial humoral response" EXACT [] +is_a: GO:0002759 ! regulation of antimicrobial humoral response +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0002922 ! positive regulation of humoral immune response +is_a: GO:0032103 ! positive regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019730 ! antimicrobial humoral response +relationship: positively_regulates GO:0019730 ! antimicrobial humoral response + +[Term] +id: GO:0002761 +name: regulation of myeloid leukocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] +is_a: GO:0045637 ! regulation of myeloid cell differentiation +is_a: GO:1902105 ! regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002573 ! myeloid leukocyte differentiation +relationship: regulates GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0002762 +name: negative regulation of myeloid leukocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] +synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] +synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] +synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] +synonym: "inhibition of myeloid leukocyte differentiation" NARROW [] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +is_a: GO:0045638 ! negative regulation of myeloid cell differentiation +is_a: GO:1902106 ! negative regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation +relationship: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0002763 +name: positive regulation of myeloid leukocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] +synonym: "activation of myeloid leukocyte differentiation" NARROW [] +synonym: "stimulation of myeloid leukocyte differentiation" NARROW [] +synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] +synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] +synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +is_a: GO:0045639 ! positive regulation of myeloid cell differentiation +is_a: GO:1902107 ! positive regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002573 ! myeloid leukocyte differentiation +relationship: positively_regulates GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0002764 +name: immune response-regulating signaling pathway +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "immune response-regulating signalling pathway" EXACT [GOC:mah] +is_a: GO:0007165 ! signal transduction +is_a: GO:0050776 ! regulation of immune response + +[Term] +id: GO:0002765 +name: immune response-inhibiting signal transduction +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response." [GOC:add, ISBN:0781735149] +is_a: GO:0002764 ! immune response-regulating signaling pathway + +[Term] +id: GO:0002766 +name: innate immune response-inhibiting signal transduction +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +is_a: GO:0002765 ! immune response-inhibiting signal transduction + +[Term] +id: GO:0002767 +name: immune response-inhibiting cell surface receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "immune response-inhibiting cell surface receptor signalling pathway" EXACT [] +is_a: GO:0002765 ! immune response-inhibiting signal transduction +is_a: GO:0002768 ! immune response-regulating cell surface receptor signaling pathway + +[Term] +id: GO:0002768 +name: immune response-regulating cell surface receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "immune response-regulating cell surface receptor signalling pathway" EXACT [] +is_a: GO:0002764 ! immune response-regulating signaling pathway +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0002769 +name: natural killer cell inhibitory signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "inhibitory KIR signaling pathway" NARROW [] +synonym: "killer cell inhibitory receptor signaling pathway" NARROW [] +synonym: "Ly49 inhibitory receptor signaling pathway" RELATED [] +synonym: "natural killer cell inhibitory signalling pathway" EXACT [] +synonym: "NK cell inhibitory signaling pathway" EXACT [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002770 +name: T cell inhibitory signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, PMID:15258309] +synonym: "T cell inhibitory signalling pathway" EXACT [] +synonym: "T lymphocyte inhibitory signaling pathway" EXACT [] +synonym: "T-cell inhibitory signaling pathway" EXACT [] +synonym: "T-lymphocyte inhibitory signaling pathway" EXACT [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002771 +name: inhibitory killer cell immunoglobulin-like receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "inhibitory killer cell immunoglobulin-like receptor signalling pathway" EXACT [] +synonym: "killer cell inhibitory receptor signaling pathway" EXACT [] +synonym: "KIR signaling pathway" EXACT [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002772 +name: inhibitory C-type lectin receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149, PMID:15771571] +synonym: "inhibitory C-type lectin receptor signalling pathway" EXACT [] +synonym: "Ly49 inhibitory receptor signaling pathway" RELATED [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002773 +name: B cell inhibitory signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, PMID:16413920] +synonym: "B cell inhibitory signalling pathway" EXACT [] +synonym: "B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway" EXACT [] +synonym: "B-cell inhibitory signaling pathway" EXACT [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002774 +name: Fc receptor mediated inhibitory signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:add, ISBN:0781735149] +synonym: "Fc receptor mediated inhibitory signalling pathway" EXACT [] +synonym: "Fc-receptor mediated inhibitory signaling pathway" EXACT [] +is_a: GO:0002767 ! immune response-inhibiting cell surface receptor signaling pathway + +[Term] +id: GO:0002775 +name: antimicrobial peptide production +namespace: biological_process +def: "The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002440 ! production of molecular mediator of immune response +relationship: part_of GO:0061844 ! antimicrobial humoral immune response mediated by antimicrobial peptide + +[Term] +id: GO:0002776 +name: antimicrobial peptide secretion +namespace: biological_process +def: "The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002790 ! peptide secretion +relationship: part_of GO:0002775 ! antimicrobial peptide production + +[Term] +id: GO:0002777 +name: antimicrobial peptide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0043043 ! peptide biosynthetic process +relationship: part_of GO:0002775 ! antimicrobial peptide production + +[Term] +id: GO:0002778 +name: antibacterial peptide production +namespace: biological_process +def: "The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002775 ! antimicrobial peptide production +relationship: part_of GO:0019731 ! antibacterial humoral response + +[Term] +id: GO:0002779 +name: antibacterial peptide secretion +namespace: biological_process +def: "The regulated release of an antibacterial peptide from a cell or a tissue." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002776 ! antimicrobial peptide secretion +relationship: part_of GO:0002778 ! antibacterial peptide production + +[Term] +id: GO:0002780 +name: antibacterial peptide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antibacterial peptide." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002777 ! antimicrobial peptide biosynthetic process +relationship: part_of GO:0002778 ! antibacterial peptide production + +[Term] +id: GO:0002781 +name: antifungal peptide production +namespace: biological_process +def: "The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002775 ! antimicrobial peptide production +relationship: part_of GO:0019732 ! antifungal humoral response + +[Term] +id: GO:0002782 +name: antifungal peptide secretion +namespace: biological_process +def: "The regulated release of an antifungal peptide from a cell or a tissue." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002776 ! antimicrobial peptide secretion +relationship: part_of GO:0002781 ! antifungal peptide production + +[Term] +id: GO:0002783 +name: antifungal peptide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antifungal peptide." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771] +is_a: GO:0002777 ! antimicrobial peptide biosynthetic process +relationship: part_of GO:0002781 ! antifungal peptide production + +[Term] +id: GO:0002784 +name: regulation of antimicrobial peptide production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antimicrobial peptide production." [GOC:add] +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +is_a: GO:0002759 ! regulation of antimicrobial humoral response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002775 ! antimicrobial peptide production +relationship: regulates GO:0002775 ! antimicrobial peptide production + +[Term] +id: GO:0002785 +name: negative regulation of antimicrobial peptide production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production." [GOC:add] +synonym: "down regulation of antimicrobial peptide production" EXACT [] +synonym: "down-regulation of antimicrobial peptide production" EXACT [] +synonym: "downregulation of antimicrobial peptide production" EXACT [] +synonym: "inhibition of antimicrobial peptide production" NARROW [] +is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response +is_a: GO:0002784 ! regulation of antimicrobial peptide production +is_a: GO:0008348 ! negative regulation of antimicrobial humoral response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002775 ! antimicrobial peptide production +relationship: negatively_regulates GO:0002775 ! antimicrobial peptide production + +[Term] +id: GO:0002786 +name: regulation of antibacterial peptide production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antibacterial peptide production." [GOC:add] +is_a: GO:0002784 ! regulation of antimicrobial peptide production +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002778 ! antibacterial peptide production +relationship: regulates GO:0002778 ! antibacterial peptide production + +[Term] +id: GO:0002787 +name: negative regulation of antibacterial peptide production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production." [GOC:add] +synonym: "down regulation of antibacterial peptide production" EXACT [] +synonym: "down-regulation of antibacterial peptide production" EXACT [] +synonym: "downregulation of antibacterial peptide production" EXACT [] +synonym: "inhibition of antibacterial peptide production" NARROW [] +is_a: GO:0002785 ! negative regulation of antimicrobial peptide production +is_a: GO:0002786 ! regulation of antibacterial peptide production +is_a: GO:1900425 ! negative regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002778 ! antibacterial peptide production +relationship: negatively_regulates GO:0002778 ! antibacterial peptide production + +[Term] +id: GO:0002788 +name: regulation of antifungal peptide production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antifungal peptide production." [GOC:add] +is_a: GO:0002784 ! regulation of antimicrobial peptide production +is_a: GO:1900150 ! regulation of defense response to fungus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002781 ! antifungal peptide production +relationship: regulates GO:0002781 ! antifungal peptide production + +[Term] +id: GO:0002789 +name: negative regulation of antifungal peptide production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production." [GOC:add] +synonym: "down regulation of antifungal peptide production" EXACT [] +synonym: "down-regulation of antifungal peptide production" EXACT [] +synonym: "downregulation of antifungal peptide production" EXACT [] +synonym: "inhibition of antifungal peptide production" NARROW [] +is_a: GO:0002785 ! negative regulation of antimicrobial peptide production +is_a: GO:0002788 ! regulation of antifungal peptide production +is_a: GO:0031348 ! negative regulation of defense response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002781 ! antifungal peptide production +relationship: negatively_regulates GO:0002781 ! antifungal peptide production + +[Term] +id: GO:0002790 +name: peptide secretion +namespace: biological_process +def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] +is_a: GO:0015833 ! peptide transport +is_a: GO:0046903 ! secretion + +[Term] +id: GO:0002791 +name: regulation of peptide secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0090087 ! regulation of peptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002790 ! peptide secretion +relationship: regulates GO:0002790 ! peptide secretion + +[Term] +id: GO:0002792 +name: negative regulation of peptide secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add] +synonym: "down regulation of peptide secretion" EXACT [] +synonym: "down-regulation of peptide secretion" EXACT [] +synonym: "downregulation of peptide secretion" EXACT [] +synonym: "inhibition of peptide secretion" NARROW [] +is_a: GO:0002791 ! regulation of peptide secretion +is_a: GO:0051048 ! negative regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002790 ! peptide secretion +relationship: negatively_regulates GO:0002790 ! peptide secretion + +[Term] +id: GO:0002793 +name: positive regulation of peptide secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add] +synonym: "activation of peptide secretion" NARROW [] +synonym: "stimulation of peptide secretion" NARROW [] +synonym: "up regulation of peptide secretion" EXACT [] +synonym: "up-regulation of peptide secretion" EXACT [] +synonym: "upregulation of peptide secretion" EXACT [] +is_a: GO:0002791 ! regulation of peptide secretion +is_a: GO:0051047 ! positive regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002790 ! peptide secretion +relationship: positively_regulates GO:0002790 ! peptide secretion + +[Term] +id: GO:0002794 +name: regulation of antimicrobial peptide secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion." [GOC:add] +is_a: GO:0002784 ! regulation of antimicrobial peptide production +is_a: GO:0002791 ! regulation of peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002776 ! antimicrobial peptide secretion +relationship: regulates GO:0002776 ! antimicrobial peptide secretion + +[Term] +id: GO:0002795 +name: negative regulation of antimicrobial peptide secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion." [GOC:add] +synonym: "down regulation of antimicrobial peptide secretion" EXACT [] +synonym: "down-regulation of antimicrobial peptide secretion" EXACT [] +synonym: "downregulation of antimicrobial peptide secretion" EXACT [] +synonym: "inhibition of antimicrobial peptide secretion" NARROW [] +is_a: GO:0002785 ! negative regulation of antimicrobial peptide production +is_a: GO:0002792 ! negative regulation of peptide secretion +is_a: GO:0002794 ! regulation of antimicrobial peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002776 ! antimicrobial peptide secretion +relationship: negatively_regulates GO:0002776 ! antimicrobial peptide secretion + +[Term] +id: GO:0002796 +name: positive regulation of antimicrobial peptide secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion." [GOC:add] +synonym: "activation of antimicrobial peptide secretion" NARROW [] +synonym: "stimulation of antimicrobial peptide secretion" NARROW [] +synonym: "up regulation of antimicrobial peptide secretion" EXACT [] +synonym: "up-regulation of antimicrobial peptide secretion" EXACT [] +synonym: "upregulation of antimicrobial peptide secretion" EXACT [] +is_a: GO:0002225 ! positive regulation of antimicrobial peptide production +is_a: GO:0002793 ! positive regulation of peptide secretion +is_a: GO:0002794 ! regulation of antimicrobial peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002776 ! antimicrobial peptide secretion +relationship: positively_regulates GO:0002776 ! antimicrobial peptide secretion + +[Term] +id: GO:0002797 +name: regulation of antibacterial peptide secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion." [GOC:add] +is_a: GO:0002786 ! regulation of antibacterial peptide production +is_a: GO:0002794 ! regulation of antimicrobial peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002779 ! antibacterial peptide secretion +relationship: regulates GO:0002779 ! antibacterial peptide secretion + +[Term] +id: GO:0002798 +name: negative regulation of antibacterial peptide secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion." [GOC:add] +synonym: "down regulation of antibacterial peptide secretion" EXACT [] +synonym: "down-regulation of antibacterial peptide secretion" EXACT [] +synonym: "downregulation of antibacterial peptide secretion" EXACT [] +synonym: "inhibition of antibacterial peptide secretion" NARROW [] +is_a: GO:0002787 ! negative regulation of antibacterial peptide production +is_a: GO:0002795 ! negative regulation of antimicrobial peptide secretion +is_a: GO:0002797 ! regulation of antibacterial peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002779 ! antibacterial peptide secretion +relationship: negatively_regulates GO:0002779 ! antibacterial peptide secretion + +[Term] +id: GO:0002799 +name: positive regulation of antibacterial peptide secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion." [GOC:add] +synonym: "activation of antibacterial peptide secretion" NARROW [] +synonym: "stimulation of antibacterial peptide secretion" NARROW [] +synonym: "up regulation of antibacterial peptide secretion" EXACT [] +synonym: "up-regulation of antibacterial peptide secretion" EXACT [] +synonym: "upregulation of antibacterial peptide secretion" EXACT [] +is_a: GO:0002796 ! positive regulation of antimicrobial peptide secretion +is_a: GO:0002797 ! regulation of antibacterial peptide secretion +is_a: GO:0002803 ! positive regulation of antibacterial peptide production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002779 ! antibacterial peptide secretion +relationship: positively_regulates GO:0002779 ! antibacterial peptide secretion + +[Term] +id: GO:0002800 +name: regulation of antifungal peptide secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antifungal peptide secretion." [GOC:add] +is_a: GO:0002788 ! regulation of antifungal peptide production +is_a: GO:0002794 ! regulation of antimicrobial peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002782 ! antifungal peptide secretion +relationship: regulates GO:0002782 ! antifungal peptide secretion + +[Term] +id: GO:0002801 +name: negative regulation of antifungal peptide secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion." [GOC:add] +synonym: "down regulation of antifungal peptide secretion" EXACT [] +synonym: "down-regulation of antifungal peptide secretion" EXACT [] +synonym: "downregulation of antifungal peptide secretion" EXACT [] +synonym: "inhibition of antifungal peptide secretion" NARROW [] +is_a: GO:0002789 ! negative regulation of antifungal peptide production +is_a: GO:0002795 ! negative regulation of antimicrobial peptide secretion +is_a: GO:0002800 ! regulation of antifungal peptide secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002782 ! antifungal peptide secretion +relationship: negatively_regulates GO:0002782 ! antifungal peptide secretion + +[Term] +id: GO:0002802 +name: positive regulation of antifungal peptide secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion." [GOC:add] +synonym: "activation of antifungal peptide secretion" NARROW [] +synonym: "stimulation of antifungal peptide secretion" NARROW [] +synonym: "up regulation of antifungal peptide secretion" EXACT [] +synonym: "up-regulation of antifungal peptide secretion" EXACT [] +synonym: "upregulation of antifungal peptide secretion" EXACT [] +is_a: GO:0002796 ! positive regulation of antimicrobial peptide secretion +is_a: GO:0002800 ! regulation of antifungal peptide secretion +is_a: GO:0002804 ! positive regulation of antifungal peptide production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002782 ! antifungal peptide secretion +relationship: positively_regulates GO:0002782 ! antifungal peptide secretion + +[Term] +id: GO:0002803 +name: positive regulation of antibacterial peptide production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production." [GOC:add] +synonym: "activation of antibacterial peptide production" NARROW [] +synonym: "stimulation of antibacterial peptide production" NARROW [] +synonym: "up regulation of antibacterial peptide production" EXACT [] +synonym: "up-regulation of antibacterial peptide production" EXACT [] +synonym: "upregulation of antibacterial peptide production" EXACT [] +is_a: GO:0002225 ! positive regulation of antimicrobial peptide production +is_a: GO:0002786 ! regulation of antibacterial peptide production +is_a: GO:1900426 ! positive regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002778 ! antibacterial peptide production +relationship: positively_regulates GO:0002778 ! antibacterial peptide production + +[Term] +id: GO:0002804 +name: positive regulation of antifungal peptide production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antifungal peptide production." [GOC:add] +synonym: "activation of antifungal peptide production" NARROW [] +synonym: "stimulation of antifungal peptide production" NARROW [] +synonym: "up regulation of antifungal peptide production" EXACT [] +synonym: "up-regulation of antifungal peptide production" EXACT [] +synonym: "upregulation of antifungal peptide production" EXACT [] +is_a: GO:0002225 ! positive regulation of antimicrobial peptide production +is_a: GO:0002788 ! regulation of antifungal peptide production +is_a: GO:0031349 ! positive regulation of defense response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002781 ! antifungal peptide production +relationship: positively_regulates GO:0002781 ! antifungal peptide production + +[Term] +id: GO:0002805 +name: regulation of antimicrobial peptide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] +is_a: GO:0002784 ! regulation of antimicrobial peptide production +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002777 ! antimicrobial peptide biosynthetic process +relationship: regulates GO:0002777 ! antimicrobial peptide biosynthetic process + +[Term] +id: GO:0002806 +name: negative regulation of antimicrobial peptide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] +synonym: "down regulation of antimicrobial peptide biosynthetic process" EXACT [] +synonym: "down-regulation of antimicrobial peptide biosynthetic process" EXACT [] +synonym: "downregulation of antimicrobial peptide biosynthetic process" EXACT [] +synonym: "inhibition of antimicrobial peptide biosynthetic process" NARROW [] +is_a: GO:0002785 ! negative regulation of antimicrobial peptide production +is_a: GO:0002805 ! regulation of antimicrobial peptide biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002777 ! antimicrobial peptide biosynthetic process +relationship: negatively_regulates GO:0002777 ! antimicrobial peptide biosynthetic process + +[Term] +id: GO:0002807 +name: positive regulation of antimicrobial peptide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] +synonym: "activation of antimicrobial peptide biosynthetic process" NARROW [] +synonym: "stimulation of antimicrobial peptide biosynthetic process" NARROW [] +synonym: "up regulation of antimicrobial peptide biosynthetic process" EXACT [] +synonym: "up-regulation of antimicrobial peptide biosynthetic process" EXACT [] +synonym: "upregulation of antimicrobial peptide biosynthetic process" EXACT [] +is_a: GO:0002225 ! positive regulation of antimicrobial peptide production +is_a: GO:0002805 ! regulation of antimicrobial peptide biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002777 ! antimicrobial peptide biosynthetic process +relationship: positively_regulates GO:0002777 ! antimicrobial peptide biosynthetic process + +[Term] +id: GO:0002808 +name: regulation of antibacterial peptide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:add] +is_a: GO:0002786 ! regulation of antibacterial peptide production +is_a: GO:0002805 ! regulation of antimicrobial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002780 ! antibacterial peptide biosynthetic process +relationship: regulates GO:0002780 ! antibacterial peptide biosynthetic process + +[Term] +id: GO:0002809 +name: negative regulation of antibacterial peptide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:add] +synonym: "down regulation of antibacterial peptide biosynthetic process" EXACT [] +synonym: "down-regulation of antibacterial peptide biosynthetic process" EXACT [] +synonym: "downregulation of antibacterial peptide biosynthetic process" EXACT [] +synonym: "inhibition of antibacterial peptide biosynthetic process" NARROW [] +is_a: GO:0002787 ! negative regulation of antibacterial peptide production +is_a: GO:0002806 ! negative regulation of antimicrobial peptide biosynthetic process +is_a: GO:0002808 ! regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002780 ! antibacterial peptide biosynthetic process +relationship: negatively_regulates GO:0002780 ! antibacterial peptide biosynthetic process + +[Term] +id: GO:0002810 +name: regulation of antifungal peptide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:add] +is_a: GO:0002788 ! regulation of antifungal peptide production +is_a: GO:0002805 ! regulation of antimicrobial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002783 ! antifungal peptide biosynthetic process +relationship: regulates GO:0002783 ! antifungal peptide biosynthetic process + +[Term] +id: GO:0002811 +name: negative regulation of antifungal peptide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:add] +synonym: "down regulation of antifungal peptide biosynthetic process" EXACT [] +synonym: "down-regulation of antifungal peptide biosynthetic process" EXACT [] +synonym: "downregulation of antifungal peptide biosynthetic process" EXACT [] +synonym: "inhibition of antifungal peptide biosynthetic process" NARROW [] +is_a: GO:0002789 ! negative regulation of antifungal peptide production +is_a: GO:0002806 ! negative regulation of antimicrobial peptide biosynthetic process +is_a: GO:0002810 ! regulation of antifungal peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002783 ! antifungal peptide biosynthetic process +relationship: negatively_regulates GO:0002783 ! antifungal peptide biosynthetic process + +[Term] +id: GO:0002812 +name: biosynthetic process of antibacterial peptides active against Gram-negative bacteria +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria." [GOC:add, PMID:11807545] +is_a: GO:0002780 ! antibacterial peptide biosynthetic process +relationship: part_of GO:0050829 ! defense response to Gram-negative bacterium + +[Term] +id: GO:0002813 +name: regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:add] +is_a: GO:0002808 ! regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria +relationship: regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria + +[Term] +id: GO:0002814 +name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:add] +synonym: "down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +synonym: "down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +synonym: "downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +synonym: "inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] +is_a: GO:0002809 ! negative regulation of antibacterial peptide biosynthetic process +is_a: GO:0002813 ! regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria +relationship: negatively_regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria + +[Term] +id: GO:0002815 +name: biosynthetic process of antibacterial peptides active against Gram-positive bacteria +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria." [GOC:add] +is_a: GO:0002780 ! antibacterial peptide biosynthetic process +relationship: part_of GO:0050830 ! defense response to Gram-positive bacterium + +[Term] +id: GO:0002816 +name: regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:add] +is_a: GO:0002808 ! regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria +relationship: regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria + +[Term] +id: GO:0002817 +name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:add] +synonym: "down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +synonym: "down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +synonym: "downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +synonym: "inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] +is_a: GO:0002809 ! negative regulation of antibacterial peptide biosynthetic process +is_a: GO:0002816 ! regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria +relationship: negatively_regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria + +[Term] +id: GO:0002819 +name: regulation of adaptive immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002250 ! adaptive immune response +relationship: regulates GO:0002250 ! adaptive immune response + +[Term] +id: GO:0002820 +name: negative regulation of adaptive immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add] +synonym: "down regulation of adaptive immune response" EXACT [] +synonym: "down-regulation of adaptive immune response" EXACT [] +synonym: "downregulation of adaptive immune response" EXACT [] +synonym: "inhibition of adaptive immune response" NARROW [] +is_a: GO:0002819 ! regulation of adaptive immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002250 ! adaptive immune response +relationship: negatively_regulates GO:0002250 ! adaptive immune response + +[Term] +id: GO:0002821 +name: positive regulation of adaptive immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add] +synonym: "activation of adaptive immune response" NARROW [] +synonym: "stimulation of adaptive immune response" NARROW [] +synonym: "up regulation of adaptive immune response" EXACT [] +synonym: "up-regulation of adaptive immune response" EXACT [] +synonym: "upregulation of adaptive immune response" EXACT [] +is_a: GO:0002819 ! regulation of adaptive immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002250 ! adaptive immune response +relationship: positively_regulates GO:0002250 ! adaptive immune response + +[Term] +id: GO:0002822 +name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] +is_a: GO:0002819 ! regulation of adaptive immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +relationship: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0002823 +name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] +is_a: GO:0002820 ! negative regulation of adaptive immune response +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +relationship: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0002824 +name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] +is_a: GO:0002821 ! positive regulation of adaptive immune response +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +relationship: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0002825 +name: regulation of T-helper 1 type immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response." [GOC:add] +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042088 ! T-helper 1 type immune response +relationship: regulates GO:0042088 ! T-helper 1 type immune response + +[Term] +id: GO:0002826 +name: negative regulation of T-helper 1 type immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response." [GOC:add] +synonym: "down regulation of T-helper 1 type immune response" EXACT [] +synonym: "down-regulation of T-helper 1 type immune response" EXACT [] +synonym: "downregulation of T-helper 1 type immune response" EXACT [] +synonym: "inhibition of T-helper 1 type immune response" NARROW [] +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0002825 ! regulation of T-helper 1 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042088 ! T-helper 1 type immune response +relationship: negatively_regulates GO:0042088 ! T-helper 1 type immune response + +[Term] +id: GO:0002827 +name: positive regulation of T-helper 1 type immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response." [GOC:add] +synonym: "activation of T-helper 1 type immune response" NARROW [] +synonym: "stimulation of T-helper 1 type immune response" NARROW [] +synonym: "up regulation of T-helper 1 type immune response" EXACT [] +synonym: "up-regulation of T-helper 1 type immune response" EXACT [] +synonym: "upregulation of T-helper 1 type immune response" EXACT [] +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0002825 ! regulation of T-helper 1 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042088 ! T-helper 1 type immune response +relationship: positively_regulates GO:0042088 ! T-helper 1 type immune response + +[Term] +id: GO:0002828 +name: regulation of type 2 immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a type 2 immune response." [GOC:add] +synonym: "regulation of T-helper 2 type immune response" NARROW [GOC:add] +synonym: "regulation of Th2 immune response" NARROW [GOC:add] +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042092 ! type 2 immune response +relationship: regulates GO:0042092 ! type 2 immune response + +[Term] +id: GO:0002829 +name: negative regulation of type 2 immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response." [GOC:add] +synonym: "down regulation of type 2 immune response" EXACT [] +synonym: "down-regulation of type 2 immune response" EXACT [] +synonym: "downregulation of type 2 immune response" EXACT [] +synonym: "inhibition of type 2 immune response" NARROW [] +synonym: "negative regulation of T-helper 2 type immune response" NARROW [GOC:add] +synonym: "negative regulation of Th2 immune response" NARROW [GOC:add] +is_a: GO:0002828 ! regulation of type 2 immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042092 ! type 2 immune response +relationship: negatively_regulates GO:0042092 ! type 2 immune response + +[Term] +id: GO:0002830 +name: positive regulation of type 2 immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a type 2 immune response." [GOC:add] +synonym: "activation of type 2 immune response" NARROW [] +synonym: "positive regulation of T-helper 2 type immune response" NARROW [GOC:add] +synonym: "positive regulation of Th2 immune response" NARROW [GOC:add] +synonym: "stimulation of type 2 immune response" NARROW [] +synonym: "up regulation of type 2 immune response" EXACT [] +synonym: "up-regulation of type 2 immune response" EXACT [] +synonym: "upregulation of type 2 immune response" EXACT [] +is_a: GO:0002828 ! regulation of type 2 immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042092 ! type 2 immune response +relationship: positively_regulates GO:0042092 ! type 2 immune response + +[Term] +id: GO:0002831 +name: regulation of response to biotic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009607 ! response to biotic stimulus +relationship: regulates GO:0009607 ! response to biotic stimulus + +[Term] +id: GO:0002832 +name: negative regulation of response to biotic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "down regulation of response to biotic stimulus" EXACT [] +synonym: "down-regulation of response to biotic stimulus" EXACT [] +synonym: "downregulation of response to biotic stimulus" EXACT [] +synonym: "inhibition of response to biotic stimulus" NARROW [] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009607 ! response to biotic stimulus +relationship: negatively_regulates GO:0009607 ! response to biotic stimulus + +[Term] +id: GO:0002833 +name: positive regulation of response to biotic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "activation of response to biotic stimulus" NARROW [] +synonym: "stimulation of response to biotic stimulus" NARROW [] +synonym: "up regulation of response to biotic stimulus" EXACT [] +synonym: "up-regulation of response to biotic stimulus" EXACT [] +synonym: "upregulation of response to biotic stimulus" EXACT [] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009607 ! response to biotic stimulus +relationship: positively_regulates GO:0009607 ! response to biotic stimulus + +[Term] +id: GO:0002834 +name: regulation of response to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a response to tumor cell." [GOC:add] +synonym: "regulation of response to tumour cell" EXACT [] +is_a: GO:0002831 ! regulation of response to biotic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002347 ! response to tumor cell +relationship: regulates GO:0002347 ! response to tumor cell + +[Term] +id: GO:0002835 +name: negative regulation of response to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell." [GOC:add] +synonym: "down regulation of response to tumor cell" EXACT [] +synonym: "down-regulation of response to tumor cell" EXACT [] +synonym: "downregulation of response to tumor cell" EXACT [] +synonym: "inhibition of response to tumor cell" NARROW [] +synonym: "negative regulation of response to tumour cell" EXACT [] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0002834 ! regulation of response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002347 ! response to tumor cell +relationship: negatively_regulates GO:0002347 ! response to tumor cell + +[Term] +id: GO:0002836 +name: positive regulation of response to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a response to tumor cell." [GOC:add] +synonym: "activation of response to tumor cell" NARROW [] +synonym: "positive regulation of response to tumour cell" EXACT [] +synonym: "stimulation of response to tumor cell" NARROW [] +synonym: "up regulation of response to tumor cell" EXACT [] +synonym: "up-regulation of response to tumor cell" EXACT [] +synonym: "upregulation of response to tumor cell" EXACT [] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0002834 ! regulation of response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002347 ! response to tumor cell +relationship: positively_regulates GO:0002347 ! response to tumor cell + +[Term] +id: GO:0002837 +name: regulation of immune response to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an immune response to tumor cell." [GOC:add] +synonym: "regulation of immune response to tumour cell" EXACT [] +is_a: GO:0002834 ! regulation of response to tumor cell +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002418 ! immune response to tumor cell +relationship: regulates GO:0002418 ! immune response to tumor cell + +[Term] +id: GO:0002838 +name: negative regulation of immune response to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell." [GOC:add] +synonym: "down regulation of immune response to tumor cell" EXACT [] +synonym: "down-regulation of immune response to tumor cell" EXACT [] +synonym: "downregulation of immune response to tumor cell" EXACT [] +synonym: "inhibition of immune response to tumor cell" NARROW [] +synonym: "negative regulation of immune response to tumour cell" EXACT [] +is_a: GO:0002835 ! negative regulation of response to tumor cell +is_a: GO:0002837 ! regulation of immune response to tumor cell +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002418 ! immune response to tumor cell +relationship: negatively_regulates GO:0002418 ! immune response to tumor cell + +[Term] +id: GO:0002839 +name: positive regulation of immune response to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell." [GOC:add] +synonym: "activation of immune response to tumor cell" NARROW [] +synonym: "positive regulation of immune response to tumour cell" EXACT [] +synonym: "stimulation of immune response to tumor cell" NARROW [] +synonym: "up regulation of immune response to tumor cell" EXACT [] +synonym: "up-regulation of immune response to tumor cell" EXACT [] +synonym: "upregulation of immune response to tumor cell" EXACT [] +is_a: GO:0002836 ! positive regulation of response to tumor cell +is_a: GO:0002837 ! regulation of immune response to tumor cell +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002418 ! immune response to tumor cell +relationship: positively_regulates GO:0002418 ! immune response to tumor cell + +[Term] +id: GO:0002840 +name: regulation of T cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell." [GOC:add] +synonym: "regulation of T cell mediated immune response to tumour cell" EXACT [] +synonym: "regulation of T lymphocyte mediated immune response to tumor cell" EXACT [] +synonym: "regulation of T-cell mediated immune response to tumor cell" EXACT [] +synonym: "regulation of T-lymphocyte mediated immune response to tumor cell" EXACT [] +is_a: GO:0002709 ! regulation of T cell mediated immunity +is_a: GO:0002837 ! regulation of immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002424 ! T cell mediated immune response to tumor cell +relationship: regulates GO:0002424 ! T cell mediated immune response to tumor cell + +[Term] +id: GO:0002841 +name: negative regulation of T cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell." [GOC:add] +synonym: "down regulation of T cell mediated immune response to tumor cell" EXACT [] +synonym: "down-regulation of T cell mediated immune response to tumor cell" EXACT [] +synonym: "downregulation of T cell mediated immune response to tumor cell" EXACT [] +synonym: "inhibition of T cell mediated immune response to tumor cell" NARROW [] +synonym: "negative regulation of T cell mediated immune response to tumour cell" EXACT [] +synonym: "negative regulation of T lymphocyte mediated immune response to tumor cell" EXACT [] +synonym: "negative regulation of T-cell mediated immune response to tumor cell" EXACT [] +synonym: "negative regulation of T-lymphocyte mediated immune response to tumor cell" EXACT [] +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +is_a: GO:0002838 ! negative regulation of immune response to tumor cell +is_a: GO:0002840 ! regulation of T cell mediated immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002424 ! T cell mediated immune response to tumor cell +relationship: negatively_regulates GO:0002424 ! T cell mediated immune response to tumor cell + +[Term] +id: GO:0002842 +name: positive regulation of T cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell." [GOC:add] +synonym: "activation of T cell mediated immune response to tumor cell" NARROW [] +synonym: "positive regulation of T cell mediated immune response to tumour cell" EXACT [] +synonym: "positive regulation of T lymphocyte mediated immune response to tumor cell" EXACT [] +synonym: "positive regulation of T-cell mediated immune response to tumor cell" EXACT [] +synonym: "positive regulation of T-lymphocyte mediated immune response to tumor cell" EXACT [] +synonym: "stimulation of T cell mediated immune response to tumor cell" NARROW [] +synonym: "up regulation of T cell mediated immune response to tumor cell" EXACT [] +synonym: "up-regulation of T cell mediated immune response to tumor cell" EXACT [] +synonym: "upregulation of T cell mediated immune response to tumor cell" EXACT [] +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +is_a: GO:0002839 ! positive regulation of immune response to tumor cell +is_a: GO:0002840 ! regulation of T cell mediated immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002424 ! T cell mediated immune response to tumor cell +relationship: positively_regulates GO:0002424 ! T cell mediated immune response to tumor cell + +[Term] +id: GO:0002843 +name: regulation of tolerance induction to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell." [GOC:add] +synonym: "regulation of tolerance induction to tumour cell" EXACT [] +is_a: GO:0002658 ! regulation of peripheral tolerance induction +is_a: GO:0002837 ! regulation of immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002413 ! tolerance induction to tumor cell +relationship: regulates GO:0002413 ! tolerance induction to tumor cell + +[Term] +id: GO:0002844 +name: negative regulation of tolerance induction to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell." [GOC:add] +synonym: "down regulation of tolerance induction to tumor cell" EXACT [] +synonym: "down-regulation of tolerance induction to tumor cell" EXACT [] +synonym: "downregulation of tolerance induction to tumor cell" EXACT [] +synonym: "inhibition of tolerance induction to tumor cell" NARROW [] +synonym: "negative regulation of tolerance induction to tumour cell" EXACT [] +is_a: GO:0002659 ! negative regulation of peripheral tolerance induction +is_a: GO:0002838 ! negative regulation of immune response to tumor cell +is_a: GO:0002843 ! regulation of tolerance induction to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002413 ! tolerance induction to tumor cell +relationship: negatively_regulates GO:0002413 ! tolerance induction to tumor cell + +[Term] +id: GO:0002845 +name: positive regulation of tolerance induction to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell." [GOC:add] +synonym: "activation of tolerance induction to tumor cell" NARROW [] +synonym: "positive regulation of tolerance induction to tumour cell" EXACT [] +synonym: "stimulation of tolerance induction to tumor cell" NARROW [] +synonym: "up regulation of tolerance induction to tumor cell" EXACT [] +synonym: "up-regulation of tolerance induction to tumor cell" EXACT [] +synonym: "upregulation of tolerance induction to tumor cell" EXACT [] +is_a: GO:0002660 ! positive regulation of peripheral tolerance induction +is_a: GO:0002839 ! positive regulation of immune response to tumor cell +is_a: GO:0002843 ! regulation of tolerance induction to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002413 ! tolerance induction to tumor cell +relationship: positively_regulates GO:0002413 ! tolerance induction to tumor cell + +[Term] +id: GO:0002846 +name: regulation of T cell tolerance induction to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell." [GOC:add] +is_a: GO:0002840 ! regulation of T cell mediated immune response to tumor cell +is_a: GO:0002843 ! regulation of tolerance induction to tumor cell +is_a: GO:0002849 ! regulation of peripheral T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002411 ! T cell tolerance induction to tumor cell +relationship: regulates GO:0002411 ! T cell tolerance induction to tumor cell + +[Term] +id: GO:0002847 +name: negative regulation of T cell tolerance induction to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell." [GOC:add] +synonym: "down regulation of T cell tolerance induction to tumor cell" EXACT [] +synonym: "down-regulation of T cell tolerance induction to tumor cell" EXACT [] +synonym: "downregulation of T cell tolerance induction to tumor cell" EXACT [] +synonym: "inhibition of T cell tolerance induction to tumor cell" NARROW [] +is_a: GO:0002841 ! negative regulation of T cell mediated immune response to tumor cell +is_a: GO:0002844 ! negative regulation of tolerance induction to tumor cell +is_a: GO:0002846 ! regulation of T cell tolerance induction to tumor cell +is_a: GO:0002850 ! negative regulation of peripheral T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002411 ! T cell tolerance induction to tumor cell +relationship: negatively_regulates GO:0002411 ! T cell tolerance induction to tumor cell + +[Term] +id: GO:0002848 +name: positive regulation of T cell tolerance induction to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell." [GOC:add] +synonym: "activation of T cell tolerance induction to tumor cell" NARROW [] +synonym: "stimulation of T cell tolerance induction to tumor cell" NARROW [] +synonym: "up regulation of T cell tolerance induction to tumor cell" EXACT [] +synonym: "up-regulation of T cell tolerance induction to tumor cell" EXACT [] +synonym: "upregulation of T cell tolerance induction to tumor cell" EXACT [] +is_a: GO:0002842 ! positive regulation of T cell mediated immune response to tumor cell +is_a: GO:0002845 ! positive regulation of tolerance induction to tumor cell +is_a: GO:0002846 ! regulation of T cell tolerance induction to tumor cell +is_a: GO:0002851 ! positive regulation of peripheral T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002411 ! T cell tolerance induction to tumor cell +relationship: positively_regulates GO:0002411 ! T cell tolerance induction to tumor cell + +[Term] +id: GO:0002849 +name: regulation of peripheral T cell tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction." [GOC:add] +is_a: GO:0002658 ! regulation of peripheral tolerance induction +is_a: GO:0002664 ! regulation of T cell tolerance induction +is_a: GO:0002709 ! regulation of T cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002458 ! peripheral T cell tolerance induction +relationship: regulates GO:0002458 ! peripheral T cell tolerance induction + +[Term] +id: GO:0002850 +name: negative regulation of peripheral T cell tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction." [GOC:add] +synonym: "down regulation of peripheral T cell tolerance induction" EXACT [] +synonym: "down-regulation of peripheral T cell tolerance induction" EXACT [] +synonym: "downregulation of peripheral T cell tolerance induction" EXACT [] +synonym: "inhibition of peripheral T cell tolerance induction" NARROW [] +is_a: GO:0002659 ! negative regulation of peripheral tolerance induction +is_a: GO:0002665 ! negative regulation of T cell tolerance induction +is_a: GO:0002710 ! negative regulation of T cell mediated immunity +is_a: GO:0002849 ! regulation of peripheral T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002458 ! peripheral T cell tolerance induction +relationship: negatively_regulates GO:0002458 ! peripheral T cell tolerance induction + +[Term] +id: GO:0002851 +name: positive regulation of peripheral T cell tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction." [GOC:add] +synonym: "activation of peripheral T cell tolerance induction" NARROW [] +synonym: "stimulation of peripheral T cell tolerance induction" NARROW [] +synonym: "up regulation of peripheral T cell tolerance induction" EXACT [] +synonym: "up-regulation of peripheral T cell tolerance induction" EXACT [] +synonym: "upregulation of peripheral T cell tolerance induction" EXACT [] +is_a: GO:0002660 ! positive regulation of peripheral tolerance induction +is_a: GO:0002666 ! positive regulation of T cell tolerance induction +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +is_a: GO:0002849 ! regulation of peripheral T cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002458 ! peripheral T cell tolerance induction +relationship: positively_regulates GO:0002458 ! peripheral T cell tolerance induction + +[Term] +id: GO:0002852 +name: regulation of T cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] +is_a: GO:0001914 ! regulation of T cell mediated cytotoxicity +is_a: GO:0002840 ! regulation of T cell mediated immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target +relationship: regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002853 +name: negative regulation of T cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] +synonym: "down regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "down-regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "downregulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "inhibition of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] +is_a: GO:0001915 ! negative regulation of T cell mediated cytotoxicity +is_a: GO:0002841 ! negative regulation of T cell mediated immune response to tumor cell +is_a: GO:0002852 ! regulation of T cell mediated cytotoxicity directed against tumor cell target +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target +relationship: negatively_regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002854 +name: positive regulation of T cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] +synonym: "activation of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] +synonym: "stimulation of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] +synonym: "up regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "up-regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "upregulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] +is_a: GO:0001916 ! positive regulation of T cell mediated cytotoxicity +is_a: GO:0002842 ! positive regulation of T cell mediated immune response to tumor cell +is_a: GO:0002852 ! regulation of T cell mediated cytotoxicity directed against tumor cell target +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target +relationship: positively_regulates GO:0002419 ! T cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002855 +name: regulation of natural killer cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell." [GOC:add] +is_a: GO:0002715 ! regulation of natural killer cell mediated immunity +is_a: GO:0002837 ! regulation of immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell +relationship: regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell + +[Term] +id: GO:0002856 +name: negative regulation of natural killer cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell." [GOC:add] +synonym: "down regulation of natural killer cell mediated immune response to tumor cell" EXACT [] +synonym: "down-regulation of natural killer cell mediated immune response to tumor cell" EXACT [] +synonym: "downregulation of natural killer cell mediated immune response to tumor cell" EXACT [] +synonym: "inhibition of natural killer cell mediated immune response to tumor cell" NARROW [] +is_a: GO:0002716 ! negative regulation of natural killer cell mediated immunity +is_a: GO:0002838 ! negative regulation of immune response to tumor cell +is_a: GO:0002855 ! regulation of natural killer cell mediated immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell +relationship: negatively_regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell + +[Term] +id: GO:0002857 +name: positive regulation of natural killer cell mediated immune response to tumor cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell." [GOC:add] +synonym: "activation of natural killer cell mediated immune response to tumor cell" NARROW [] +synonym: "stimulation of natural killer cell mediated immune response to tumor cell" NARROW [] +synonym: "up regulation of natural killer cell mediated immune response to tumor cell" EXACT [] +synonym: "up-regulation of natural killer cell mediated immune response to tumor cell" EXACT [] +synonym: "upregulation of natural killer cell mediated immune response to tumor cell" EXACT [] +is_a: GO:0002717 ! positive regulation of natural killer cell mediated immunity +is_a: GO:0002839 ! positive regulation of immune response to tumor cell +is_a: GO:0002855 ! regulation of natural killer cell mediated immune response to tumor cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell +relationship: positively_regulates GO:0002423 ! natural killer cell mediated immune response to tumor cell + +[Term] +id: GO:0002858 +name: regulation of natural killer cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] +is_a: GO:0002855 ! regulation of natural killer cell mediated immune response to tumor cell +is_a: GO:0042269 ! regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target +relationship: regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002859 +name: negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] +synonym: "down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] +is_a: GO:0002856 ! negative regulation of natural killer cell mediated immune response to tumor cell +is_a: GO:0002858 ! regulation of natural killer cell mediated cytotoxicity directed against tumor cell target +is_a: GO:0045953 ! negative regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target +relationship: negatively_regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002860 +name: positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] +synonym: "activation of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] +synonym: "stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] +synonym: "up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +synonym: "upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] +is_a: GO:0002857 ! positive regulation of natural killer cell mediated immune response to tumor cell +is_a: GO:0002858 ! regulation of natural killer cell mediated cytotoxicity directed against tumor cell target +is_a: GO:0045954 ! positive regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target +relationship: positively_regulates GO:0002420 ! natural killer cell mediated cytotoxicity directed against tumor cell target + +[Term] +id: GO:0002861 +name: regulation of inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus." [GOC:add] +is_a: GO:0050727 ! regulation of inflammatory response +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002437 ! inflammatory response to antigenic stimulus +relationship: regulates GO:0002437 ! inflammatory response to antigenic stimulus + +[Term] +id: GO:0002862 +name: negative regulation of inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "down regulation of inflammatory response to antigenic stimulus" EXACT [] +synonym: "down-regulation of inflammatory response to antigenic stimulus" EXACT [] +synonym: "downregulation of inflammatory response to antigenic stimulus" EXACT [] +synonym: "inhibition of inflammatory response to antigenic stimulus" NARROW [] +is_a: GO:0002861 ! regulation of inflammatory response to antigenic stimulus +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002437 ! inflammatory response to antigenic stimulus +relationship: negatively_regulates GO:0002437 ! inflammatory response to antigenic stimulus + +[Term] +id: GO:0002863 +name: positive regulation of inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "activation of inflammatory response to antigenic stimulus" NARROW [] +synonym: "stimulation of inflammatory response to antigenic stimulus" NARROW [] +synonym: "up regulation of inflammatory response to antigenic stimulus" EXACT [] +synonym: "up-regulation of inflammatory response to antigenic stimulus" EXACT [] +synonym: "upregulation of inflammatory response to antigenic stimulus" EXACT [] +is_a: GO:0002861 ! regulation of inflammatory response to antigenic stimulus +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002437 ! inflammatory response to antigenic stimulus +relationship: positively_regulates GO:0002437 ! inflammatory response to antigenic stimulus + +[Term] +id: GO:0002864 +name: regulation of acute inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus." [GOC:add] +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0002861 ! regulation of inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002438 ! acute inflammatory response to antigenic stimulus +relationship: regulates GO:0002438 ! acute inflammatory response to antigenic stimulus + +[Term] +id: GO:0002865 +name: negative regulation of acute inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "down regulation of acute inflammatory response to antigenic stimulus" EXACT [] +synonym: "down-regulation of acute inflammatory response to antigenic stimulus" EXACT [] +synonym: "downregulation of acute inflammatory response to antigenic stimulus" EXACT [] +synonym: "inhibition of acute inflammatory response to antigenic stimulus" NARROW [] +is_a: GO:0002674 ! negative regulation of acute inflammatory response +is_a: GO:0002862 ! negative regulation of inflammatory response to antigenic stimulus +is_a: GO:0002864 ! regulation of acute inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002438 ! acute inflammatory response to antigenic stimulus +relationship: negatively_regulates GO:0002438 ! acute inflammatory response to antigenic stimulus + +[Term] +id: GO:0002866 +name: positive regulation of acute inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "activation of acute inflammatory response to antigenic stimulus" NARROW [] +synonym: "stimulation of acute inflammatory response to antigenic stimulus" NARROW [] +synonym: "up regulation of acute inflammatory response to antigenic stimulus" EXACT [] +synonym: "up-regulation of acute inflammatory response to antigenic stimulus" EXACT [] +synonym: "upregulation of acute inflammatory response to antigenic stimulus" EXACT [] +is_a: GO:0002675 ! positive regulation of acute inflammatory response +is_a: GO:0002863 ! positive regulation of inflammatory response to antigenic stimulus +is_a: GO:0002864 ! regulation of acute inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002438 ! acute inflammatory response to antigenic stimulus +relationship: positively_regulates GO:0002438 ! acute inflammatory response to antigenic stimulus + +[Term] +id: GO:0002867 +name: regulation of B cell deletion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell deletion." [GOC:add] +synonym: "regulation of B lymphocyte deletion" EXACT [] +synonym: "regulation of B-cell deletion" EXACT [] +synonym: "regulation of B-lymphocyte deletion" EXACT [] +is_a: GO:0002661 ! regulation of B cell tolerance induction +is_a: GO:0002902 ! regulation of B cell apoptotic process +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002516 ! B cell deletion +relationship: regulates GO:0002516 ! B cell deletion + +[Term] +id: GO:0002868 +name: negative regulation of B cell deletion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion." [GOC:add] +synonym: "down regulation of B cell deletion" EXACT [] +synonym: "down-regulation of B cell deletion" EXACT [] +synonym: "downregulation of B cell deletion" EXACT [] +synonym: "inhibition of B cell deletion" NARROW [] +synonym: "negative regulation of B lymphocyte deletion" EXACT [] +synonym: "negative regulation of B-cell deletion" EXACT [] +synonym: "negative regulation of B-lymphocyte deletion" EXACT [] +is_a: GO:0002662 ! negative regulation of B cell tolerance induction +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0002867 ! regulation of B cell deletion +is_a: GO:0002903 ! negative regulation of B cell apoptotic process +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002516 ! B cell deletion +relationship: negatively_regulates GO:0002516 ! B cell deletion + +[Term] +id: GO:0002869 +name: positive regulation of B cell deletion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell deletion." [GOC:add] +synonym: "activation of B cell deletion" NARROW [] +synonym: "positive regulation of B lymphocyte deletion" EXACT [] +synonym: "positive regulation of B-cell deletion" EXACT [] +synonym: "positive regulation of B-lymphocyte deletion" EXACT [] +synonym: "stimulation of B cell deletion" NARROW [] +synonym: "up regulation of B cell deletion" EXACT [] +synonym: "up-regulation of B cell deletion" EXACT [] +synonym: "upregulation of B cell deletion" EXACT [] +is_a: GO:0002663 ! positive regulation of B cell tolerance induction +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0002867 ! regulation of B cell deletion +is_a: GO:0002904 ! positive regulation of B cell apoptotic process +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002516 ! B cell deletion +relationship: positively_regulates GO:0002516 ! B cell deletion + +[Term] +id: GO:0002870 +name: T cell anergy +namespace: biological_process +def: "Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction." [GOC:add, ISBN:0781735149] +synonym: "T lymphocyte anergy" EXACT [] +synonym: "T-cell anergy" EXACT [] +synonym: "T-lymphocyte anergy" EXACT [] +is_a: GO:0002249 ! lymphocyte anergy +is_a: GO:0002517 ! T cell tolerance induction + +[Term] +id: GO:0002871 +name: regulation of natural killer cell tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction." [GOC:add] +synonym: "regulation of NK cell tolerance induction" EXACT [] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002519 ! natural killer cell tolerance induction +relationship: regulates GO:0002519 ! natural killer cell tolerance induction + +[Term] +id: GO:0002872 +name: negative regulation of natural killer cell tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction." [GOC:add] +synonym: "down regulation of natural killer cell tolerance induction" EXACT [] +synonym: "down-regulation of natural killer cell tolerance induction" EXACT [] +synonym: "downregulation of natural killer cell tolerance induction" EXACT [] +synonym: "inhibition of natural killer cell tolerance induction" NARROW [] +synonym: "negative regulation of NK cell tolerance induction" EXACT [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0002871 ! regulation of natural killer cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002519 ! natural killer cell tolerance induction +relationship: negatively_regulates GO:0002519 ! natural killer cell tolerance induction + +[Term] +id: GO:0002873 +name: positive regulation of natural killer cell tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction." [GOC:add] +synonym: "activation of natural killer cell tolerance induction" NARROW [] +synonym: "positive regulation of NK cell tolerance induction" EXACT [] +synonym: "stimulation of natural killer cell tolerance induction" NARROW [] +synonym: "up regulation of natural killer cell tolerance induction" EXACT [] +synonym: "up-regulation of natural killer cell tolerance induction" EXACT [] +synonym: "upregulation of natural killer cell tolerance induction" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0002871 ! regulation of natural killer cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002519 ! natural killer cell tolerance induction +relationship: positively_regulates GO:0002519 ! natural killer cell tolerance induction + +[Term] +id: GO:0002874 +name: regulation of chronic inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus." [GOC:add] +is_a: GO:0002676 ! regulation of chronic inflammatory response +is_a: GO:0002861 ! regulation of inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus +relationship: regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus + +[Term] +id: GO:0002875 +name: negative regulation of chronic inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "down regulation of chronic inflammatory response to antigenic stimulus" EXACT [] +synonym: "down-regulation of chronic inflammatory response to antigenic stimulus" EXACT [] +synonym: "downregulation of chronic inflammatory response to antigenic stimulus" EXACT [] +synonym: "inhibition of chronic inflammatory response to antigenic stimulus" NARROW [] +is_a: GO:0002677 ! negative regulation of chronic inflammatory response +is_a: GO:0002862 ! negative regulation of inflammatory response to antigenic stimulus +is_a: GO:0002874 ! regulation of chronic inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus +relationship: negatively_regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus + +[Term] +id: GO:0002876 +name: positive regulation of chronic inflammatory response to antigenic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus." [GOC:add] +synonym: "activation of chronic inflammatory response to antigenic stimulus" NARROW [] +synonym: "stimulation of chronic inflammatory response to antigenic stimulus" NARROW [] +synonym: "up regulation of chronic inflammatory response to antigenic stimulus" EXACT [] +synonym: "up-regulation of chronic inflammatory response to antigenic stimulus" EXACT [] +synonym: "upregulation of chronic inflammatory response to antigenic stimulus" EXACT [] +is_a: GO:0002678 ! positive regulation of chronic inflammatory response +is_a: GO:0002863 ! positive regulation of inflammatory response to antigenic stimulus +is_a: GO:0002874 ! regulation of chronic inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus +relationship: positively_regulates GO:0002439 ! chronic inflammatory response to antigenic stimulus + +[Term] +id: GO:0002877 +name: regulation of acute inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus." [GOC:add] +is_a: GO:0002673 ! regulation of acute inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus +relationship: regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002878 +name: negative regulation of acute inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus." [GOC:add] +synonym: "down regulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "down-regulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "downregulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "inhibition of acute inflammatory response to non-antigenic stimulus" NARROW [] +is_a: GO:0002674 ! negative regulation of acute inflammatory response +is_a: GO:0002877 ! regulation of acute inflammatory response to non-antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus +relationship: negatively_regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002879 +name: positive regulation of acute inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus." [GOC:add] +synonym: "activation of acute inflammatory response to non-antigenic stimulus" NARROW [] +synonym: "stimulation of acute inflammatory response to non-antigenic stimulus" NARROW [] +synonym: "up regulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "up-regulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "upregulation of acute inflammatory response to non-antigenic stimulus" EXACT [] +is_a: GO:0002675 ! positive regulation of acute inflammatory response +is_a: GO:0002877 ! regulation of acute inflammatory response to non-antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus +relationship: positively_regulates GO:0002525 ! acute inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002880 +name: regulation of chronic inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus." [GOC:add] +is_a: GO:0002676 ! regulation of chronic inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus +relationship: regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002881 +name: negative regulation of chronic inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus." [GOC:add] +synonym: "down regulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "down-regulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "downregulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "inhibition of chronic inflammatory response to non-antigenic stimulus" NARROW [] +is_a: GO:0002677 ! negative regulation of chronic inflammatory response +is_a: GO:0002880 ! regulation of chronic inflammatory response to non-antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus +relationship: negatively_regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002882 +name: positive regulation of chronic inflammatory response to non-antigenic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus." [GOC:add] +synonym: "activation of chronic inflammatory response to non-antigenic stimulus" NARROW [] +synonym: "stimulation of chronic inflammatory response to non-antigenic stimulus" NARROW [] +synonym: "up regulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "up-regulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +synonym: "upregulation of chronic inflammatory response to non-antigenic stimulus" EXACT [] +is_a: GO:0002678 ! positive regulation of chronic inflammatory response +is_a: GO:0002880 ! regulation of chronic inflammatory response to non-antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus +relationship: positively_regulates GO:0002545 ! chronic inflammatory response to non-antigenic stimulus + +[Term] +id: GO:0002883 +name: regulation of hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of hypersensitivity." [GOC:add] +is_a: GO:0002864 ! regulation of acute inflammatory response to antigenic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002524 ! hypersensitivity +relationship: regulates GO:0002524 ! hypersensitivity + +[Term] +id: GO:0002884 +name: negative regulation of hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity." [GOC:add] +synonym: "down regulation of hypersensitivity" EXACT [] +synonym: "down-regulation of hypersensitivity" EXACT [] +synonym: "downregulation of hypersensitivity" EXACT [] +synonym: "inhibition of hypersensitivity" NARROW [] +is_a: GO:0002865 ! negative regulation of acute inflammatory response to antigenic stimulus +is_a: GO:0002883 ! regulation of hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002524 ! hypersensitivity +relationship: negatively_regulates GO:0002524 ! hypersensitivity + +[Term] +id: GO:0002885 +name: positive regulation of hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of hypersensitivity." [GOC:add] +synonym: "activation of hypersensitivity" NARROW [] +synonym: "stimulation of hypersensitivity" NARROW [] +synonym: "up regulation of hypersensitivity" EXACT [] +synonym: "up-regulation of hypersensitivity" EXACT [] +synonym: "upregulation of hypersensitivity" EXACT [] +is_a: GO:0002866 ! positive regulation of acute inflammatory response to antigenic stimulus +is_a: GO:0002883 ! regulation of hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002524 ! hypersensitivity +relationship: positively_regulates GO:0002524 ! hypersensitivity + +[Term] +id: GO:0002886 +name: regulation of myeloid leukocyte mediated immunity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] +is_a: GO:0002703 ! regulation of leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002444 ! myeloid leukocyte mediated immunity +relationship: regulates GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002887 +name: negative regulation of myeloid leukocyte mediated immunity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] +synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT [] +synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT [] +synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT [] +synonym: "inhibition of myeloid leukocyte mediated immunity" NARROW [] +is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity +relationship: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002888 +name: positive regulation of myeloid leukocyte mediated immunity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] +synonym: "activation of myeloid leukocyte mediated immunity" NARROW [] +synonym: "stimulation of myeloid leukocyte mediated immunity" NARROW [] +synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT [] +synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT [] +synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT [] +is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity +relationship: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity + +[Term] +id: GO:0002889 +name: regulation of immunoglobulin mediated immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response." [GOC:add] +is_a: GO:0002712 ! regulation of B cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016064 ! immunoglobulin mediated immune response +relationship: regulates GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002890 +name: negative regulation of immunoglobulin mediated immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response." [GOC:add] +synonym: "down regulation of immunoglobulin mediated immune response" EXACT [] +synonym: "down-regulation of immunoglobulin mediated immune response" EXACT [] +synonym: "downregulation of immunoglobulin mediated immune response" EXACT [] +synonym: "inhibition of immunoglobulin mediated immune response" NARROW [] +is_a: GO:0002713 ! negative regulation of B cell mediated immunity +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016064 ! immunoglobulin mediated immune response +relationship: negatively_regulates GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002891 +name: positive regulation of immunoglobulin mediated immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response." [GOC:add] +synonym: "activation of immunoglobulin mediated immune response" NARROW [] +synonym: "stimulation of immunoglobulin mediated immune response" NARROW [] +synonym: "up regulation of immunoglobulin mediated immune response" EXACT [] +synonym: "up-regulation of immunoglobulin mediated immune response" EXACT [] +synonym: "upregulation of immunoglobulin mediated immune response" EXACT [] +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016064 ! immunoglobulin mediated immune response +relationship: positively_regulates GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0002892 +name: regulation of type II hypersensitivity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type II hypersensitivity." [GOC:add] +is_a: GO:0002883 ! regulation of hypersensitivity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002445 ! type II hypersensitivity +relationship: regulates GO:0002445 ! type II hypersensitivity + +[Term] +id: GO:0002893 +name: negative regulation of type II hypersensitivity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity." [GOC:add] +synonym: "down regulation of type II hypersensitivity" EXACT [] +synonym: "down-regulation of type II hypersensitivity" EXACT [] +synonym: "downregulation of type II hypersensitivity" EXACT [] +synonym: "inhibition of type II hypersensitivity" NARROW [] +is_a: GO:0002884 ! negative regulation of hypersensitivity +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0002890 ! negative regulation of immunoglobulin mediated immune response +is_a: GO:0002892 ! regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002445 ! type II hypersensitivity +relationship: negatively_regulates GO:0002445 ! type II hypersensitivity + +[Term] +id: GO:0002894 +name: positive regulation of type II hypersensitivity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity." [GOC:add] +synonym: "activation of type II hypersensitivity" NARROW [] +synonym: "stimulation of type II hypersensitivity" NARROW [] +synonym: "up regulation of type II hypersensitivity" EXACT [] +synonym: "up-regulation of type II hypersensitivity" EXACT [] +synonym: "upregulation of type II hypersensitivity" EXACT [] +is_a: GO:0002885 ! positive regulation of hypersensitivity +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +is_a: GO:0002892 ! regulation of type II hypersensitivity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002445 ! type II hypersensitivity +relationship: positively_regulates GO:0002445 ! type II hypersensitivity + +[Term] +id: GO:0002895 +name: regulation of central B cell tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of central B cell tolerance induction." [GOC:add] +is_a: GO:0002646 ! regulation of central tolerance induction +is_a: GO:0002661 ! regulation of B cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002510 ! central B cell tolerance induction +relationship: regulates GO:0002510 ! central B cell tolerance induction + +[Term] +id: GO:0002896 +name: negative regulation of central B cell tolerance induction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction." [GOC:add] +synonym: "down regulation of central B cell tolerance induction" EXACT [] +synonym: "down-regulation of central B cell tolerance induction" EXACT [] +synonym: "downregulation of central B cell tolerance induction" EXACT [] +synonym: "inhibition of central B cell tolerance induction" NARROW [] +is_a: GO:0002647 ! negative regulation of central tolerance induction +is_a: GO:0002662 ! negative regulation of B cell tolerance induction +is_a: GO:0002895 ! regulation of central B cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002510 ! central B cell tolerance induction +relationship: negatively_regulates GO:0002510 ! central B cell tolerance induction + +[Term] +id: GO:0002897 +name: positive regulation of central B cell tolerance induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction." [GOC:add] +synonym: "activation of central B cell tolerance induction" NARROW [] +synonym: "stimulation of central B cell tolerance induction" NARROW [] +synonym: "up regulation of central B cell tolerance induction" EXACT [] +synonym: "up-regulation of central B cell tolerance induction" EXACT [] +synonym: "upregulation of central B cell tolerance induction" EXACT [] +is_a: GO:0002648 ! positive regulation of central tolerance induction +is_a: GO:0002663 ! positive regulation of B cell tolerance induction +is_a: GO:0002895 ! regulation of central B cell tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002510 ! central B cell tolerance induction +relationship: positively_regulates GO:0002510 ! central B cell tolerance induction + +[Term] +id: GO:0002898 +name: regulation of central B cell deletion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of central B cell deletion." [GOC:add] +is_a: GO:0002867 ! regulation of B cell deletion +is_a: GO:0002895 ! regulation of central B cell tolerance induction +is_a: GO:0045577 ! regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002342 ! central B cell deletion +relationship: regulates GO:0002342 ! central B cell deletion + +[Term] +id: GO:0002899 +name: negative regulation of central B cell deletion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion." [GOC:add] +synonym: "down regulation of central B cell deletion" EXACT [] +synonym: "down-regulation of central B cell deletion" EXACT [] +synonym: "downregulation of central B cell deletion" EXACT [] +synonym: "inhibition of central B cell deletion" NARROW [] +is_a: GO:0002868 ! negative regulation of B cell deletion +is_a: GO:0002896 ! negative regulation of central B cell tolerance induction +is_a: GO:0002898 ! regulation of central B cell deletion +is_a: GO:0045578 ! negative regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002342 ! central B cell deletion +relationship: negatively_regulates GO:0002342 ! central B cell deletion + +[Term] +id: GO:0002900 +name: positive regulation of central B cell deletion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of central B cell deletion." [GOC:add] +synonym: "activation of central B cell deletion" NARROW [] +synonym: "stimulation of central B cell deletion" NARROW [] +synonym: "up regulation of central B cell deletion" EXACT [] +synonym: "up-regulation of central B cell deletion" EXACT [] +synonym: "upregulation of central B cell deletion" EXACT [] +is_a: GO:0002869 ! positive regulation of B cell deletion +is_a: GO:0002897 ! positive regulation of central B cell tolerance induction +is_a: GO:0002898 ! regulation of central B cell deletion +is_a: GO:0045579 ! positive regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002342 ! central B cell deletion +relationship: positively_regulates GO:0002342 ! central B cell deletion + +[Term] +id: GO:0002901 +name: mature B cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a B cell that is mature, having left the bone marrow." [CL:0000785, GOC:add, GOC:mtg_apoptosis, ISBN:0781735149] +synonym: "apoptosis of mature B cells" EXACT [] +synonym: "apoptosis of mature B lymphocytes" EXACT [] +synonym: "apoptosis of mature B-cells" EXACT [] +synonym: "apoptosis of mature B-lymphocytes" EXACT [] +synonym: "mature B cell apoptosis" NARROW [] +synonym: "mature B cell programmed cell death by apoptosis" EXACT [] +synonym: "mature B lymphocyte apoptosis" EXACT [] +synonym: "mature B lymphocyte programmed cell death by apoptosis" EXACT [] +synonym: "mature B-cell apoptosis" EXACT [] +synonym: "mature B-cell programmed cell death by apoptosis" EXACT [] +synonym: "mature B-lymphocyte apoptosis" EXACT [] +synonym: "mature B-lymphocyte programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of mature B cells by apoptosis" EXACT [] +synonym: "programmed cell death of mature B lymphocytes by apoptosis" EXACT [] +synonym: "programmed cell death of mature B-cells by apoptosis" EXACT [] +synonym: "programmed cell death of mature B-lymphocytes by apoptosis" EXACT [] +synonym: "programmed cell death, mature B cells" EXACT [] +synonym: "programmed cell death, mature B lymphocytes" EXACT [] +synonym: "programmed cell death, mature B-cells" EXACT [] +synonym: "programmed cell death, mature B-lymphocytes" EXACT [] +is_a: GO:0001783 ! B cell apoptotic process +relationship: part_of GO:0001782 ! B cell homeostasis + +[Term] +id: GO:0002902 +name: regulation of B cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "regulation of B cell apoptosis" NARROW [] +is_a: GO:0070228 ! regulation of lymphocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001783 ! B cell apoptotic process +relationship: regulates GO:0001783 ! B cell apoptotic process + +[Term] +id: GO:0002903 +name: negative regulation of B cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "down regulation of B cell apoptosis" EXACT [] +synonym: "down-regulation of B cell apoptosis" EXACT [] +synonym: "downregulation of B cell apoptosis" EXACT [] +synonym: "inhibition of B cell apoptosis" NARROW [] +synonym: "negative regulation of B cell apoptosis" NARROW [] +is_a: GO:0002902 ! regulation of B cell apoptotic process +is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001783 ! B cell apoptotic process +relationship: negatively_regulates GO:0001783 ! B cell apoptotic process + +[Term] +id: GO:0002904 +name: positive regulation of B cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "activation of B cell apoptosis" NARROW [] +synonym: "positive regulation of B cell apoptosis" NARROW [] +synonym: "stimulation of B cell apoptosis" NARROW [] +synonym: "up regulation of B cell apoptosis" EXACT [] +synonym: "up-regulation of B cell apoptosis" EXACT [] +synonym: "upregulation of B cell apoptosis" EXACT [] +is_a: GO:0002902 ! regulation of B cell apoptotic process +is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001783 ! B cell apoptotic process +relationship: positively_regulates GO:0001783 ! B cell apoptotic process + +[Term] +id: GO:0002905 +name: regulation of mature B cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "regulation of mature B cell apoptosis" NARROW [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0002902 ! regulation of B cell apoptotic process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002901 ! mature B cell apoptotic process +relationship: regulates GO:0002901 ! mature B cell apoptotic process + +[Term] +id: GO:0002906 +name: negative regulation of mature B cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "down regulation of mature B cell apoptosis" EXACT [] +synonym: "down-regulation of mature B cell apoptosis" EXACT [] +synonym: "downregulation of mature B cell apoptosis" EXACT [] +synonym: "inhibition of mature B cell apoptosis" NARROW [] +synonym: "negative regulation of mature B cell apoptosis" NARROW [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0002903 ! negative regulation of B cell apoptotic process +is_a: GO:0002905 ! regulation of mature B cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002901 ! mature B cell apoptotic process +relationship: negatively_regulates GO:0002901 ! mature B cell apoptotic process + +[Term] +id: GO:0002907 +name: positive regulation of mature B cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "activation of mature B cell apoptosis" NARROW [] +synonym: "positive regulation of mature B cell apoptosis" NARROW [] +synonym: "stimulation of mature B cell apoptosis" NARROW [] +synonym: "up regulation of mature B cell apoptosis" EXACT [] +synonym: "up-regulation of mature B cell apoptosis" EXACT [] +synonym: "upregulation of mature B cell apoptosis" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0002904 ! positive regulation of B cell apoptotic process +is_a: GO:0002905 ! regulation of mature B cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002901 ! mature B cell apoptotic process +relationship: positively_regulates GO:0002901 ! mature B cell apoptotic process + +[Term] +id: GO:0002908 +name: regulation of peripheral B cell deletion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] +is_a: GO:0002658 ! regulation of peripheral tolerance induction +is_a: GO:0002712 ! regulation of B cell mediated immunity +is_a: GO:0002867 ! regulation of B cell deletion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002454 ! peripheral B cell deletion +relationship: regulates GO:0002454 ! peripheral B cell deletion + +[Term] +id: GO:0002909 +name: negative regulation of peripheral B cell deletion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] +synonym: "down regulation of peripheral B cell deletion" EXACT [] +synonym: "down-regulation of peripheral B cell deletion" EXACT [] +synonym: "downregulation of peripheral B cell deletion" EXACT [] +synonym: "inhibition of peripheral B cell deletion" NARROW [] +is_a: GO:0002659 ! negative regulation of peripheral tolerance induction +is_a: GO:0002713 ! negative regulation of B cell mediated immunity +is_a: GO:0002868 ! negative regulation of B cell deletion +is_a: GO:0002908 ! regulation of peripheral B cell deletion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002454 ! peripheral B cell deletion +relationship: negatively_regulates GO:0002454 ! peripheral B cell deletion + +[Term] +id: GO:0002910 +name: positive regulation of peripheral B cell deletion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] +synonym: "activation of peripheral B cell deletion" NARROW [] +synonym: "stimulation of peripheral B cell deletion" NARROW [] +synonym: "up regulation of peripheral B cell deletion" EXACT [] +synonym: "up-regulation of peripheral B cell deletion" EXACT [] +synonym: "upregulation of peripheral B cell deletion" EXACT [] +is_a: GO:0002660 ! positive regulation of peripheral tolerance induction +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +is_a: GO:0002869 ! positive regulation of B cell deletion +is_a: GO:0002908 ! regulation of peripheral B cell deletion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002454 ! peripheral B cell deletion +relationship: positively_regulates GO:0002454 ! peripheral B cell deletion + +[Term] +id: GO:0002911 +name: regulation of lymphocyte anergy +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of lymphocyte anergy." [GOC:add] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002249 ! lymphocyte anergy +relationship: regulates GO:0002249 ! lymphocyte anergy + +[Term] +id: GO:0002912 +name: negative regulation of lymphocyte anergy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy." [GOC:add] +synonym: "down regulation of lymphocyte anergy" EXACT [] +synonym: "down-regulation of lymphocyte anergy" EXACT [] +synonym: "downregulation of lymphocyte anergy" EXACT [] +synonym: "inhibition of lymphocyte anergy" NARROW [] +is_a: GO:0002644 ! negative regulation of tolerance induction +is_a: GO:0002911 ! regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002249 ! lymphocyte anergy +relationship: negatively_regulates GO:0002249 ! lymphocyte anergy + +[Term] +id: GO:0002913 +name: positive regulation of lymphocyte anergy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy." [GOC:add] +synonym: "activation of lymphocyte anergy" NARROW [] +synonym: "stimulation of lymphocyte anergy" NARROW [] +synonym: "up regulation of lymphocyte anergy" EXACT [] +synonym: "up-regulation of lymphocyte anergy" EXACT [] +synonym: "upregulation of lymphocyte anergy" EXACT [] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0002911 ! regulation of lymphocyte anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002249 ! lymphocyte anergy +relationship: positively_regulates GO:0002249 ! lymphocyte anergy + +[Term] +id: GO:0002914 +name: regulation of central B cell anergy +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of central B cell anergy." [GOC:add] +is_a: GO:0002670 ! regulation of B cell anergy +is_a: GO:0002895 ! regulation of central B cell tolerance induction +is_a: GO:0045577 ! regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002341 ! central B cell anergy +relationship: regulates GO:0002341 ! central B cell anergy + +[Term] +id: GO:0002915 +name: negative regulation of central B cell anergy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy." [GOC:add] +synonym: "down regulation of central B cell anergy" EXACT [] +synonym: "down-regulation of central B cell anergy" EXACT [] +synonym: "downregulation of central B cell anergy" EXACT [] +synonym: "inhibition of central B cell anergy" NARROW [] +is_a: GO:0002671 ! negative regulation of B cell anergy +is_a: GO:0002896 ! negative regulation of central B cell tolerance induction +is_a: GO:0002914 ! regulation of central B cell anergy +is_a: GO:0045578 ! negative regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002341 ! central B cell anergy +relationship: negatively_regulates GO:0002341 ! central B cell anergy + +[Term] +id: GO:0002916 +name: positive regulation of central B cell anergy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of central B cell anergy." [GOC:add] +synonym: "activation of central B cell anergy" NARROW [] +synonym: "stimulation of central B cell anergy" NARROW [] +synonym: "up regulation of central B cell anergy" EXACT [] +synonym: "up-regulation of central B cell anergy" EXACT [] +synonym: "upregulation of central B cell anergy" EXACT [] +is_a: GO:0002672 ! positive regulation of B cell anergy +is_a: GO:0002897 ! positive regulation of central B cell tolerance induction +is_a: GO:0002914 ! regulation of central B cell anergy +is_a: GO:0045579 ! positive regulation of B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002341 ! central B cell anergy +relationship: positively_regulates GO:0002341 ! central B cell anergy + +[Term] +id: GO:0002917 +name: regulation of peripheral B cell anergy +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of peripheral B cell anergy." [GOC:add] +is_a: GO:0002658 ! regulation of peripheral tolerance induction +is_a: GO:0002670 ! regulation of B cell anergy +is_a: GO:0002712 ! regulation of B cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002453 ! peripheral B cell anergy +relationship: regulates GO:0002453 ! peripheral B cell anergy + +[Term] +id: GO:0002918 +name: negative regulation of peripheral B cell anergy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy." [GOC:add] +synonym: "down regulation of peripheral B cell anergy" EXACT [] +synonym: "down-regulation of peripheral B cell anergy" EXACT [] +synonym: "downregulation of peripheral B cell anergy" EXACT [] +synonym: "inhibition of peripheral B cell anergy" NARROW [] +is_a: GO:0002659 ! negative regulation of peripheral tolerance induction +is_a: GO:0002671 ! negative regulation of B cell anergy +is_a: GO:0002713 ! negative regulation of B cell mediated immunity +is_a: GO:0002917 ! regulation of peripheral B cell anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002453 ! peripheral B cell anergy +relationship: negatively_regulates GO:0002453 ! peripheral B cell anergy + +[Term] +id: GO:0002919 +name: positive regulation of peripheral B cell anergy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy." [GOC:add] +synonym: "activation of peripheral B cell anergy" NARROW [] +synonym: "stimulation of peripheral B cell anergy" NARROW [] +synonym: "up regulation of peripheral B cell anergy" EXACT [] +synonym: "up-regulation of peripheral B cell anergy" EXACT [] +synonym: "upregulation of peripheral B cell anergy" EXACT [] +is_a: GO:0002660 ! positive regulation of peripheral tolerance induction +is_a: GO:0002672 ! positive regulation of B cell anergy +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +is_a: GO:0002917 ! regulation of peripheral B cell anergy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002453 ! peripheral B cell anergy +relationship: positively_regulates GO:0002453 ! peripheral B cell anergy + +[Term] +id: GO:0002920 +name: regulation of humoral immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a humoral immune response." [GOC:add] +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006959 ! humoral immune response +relationship: regulates GO:0006959 ! humoral immune response + +[Term] +id: GO:0002921 +name: negative regulation of humoral immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response." [GOC:add] +synonym: "down regulation of humoral immune response" EXACT [] +synonym: "down-regulation of humoral immune response" EXACT [] +synonym: "downregulation of humoral immune response" EXACT [] +synonym: "inhibition of humoral immune response" NARROW [] +is_a: GO:0002920 ! regulation of humoral immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006959 ! humoral immune response +relationship: negatively_regulates GO:0006959 ! humoral immune response + +[Term] +id: GO:0002922 +name: positive regulation of humoral immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a humoral immune response." [GOC:add] +synonym: "activation of humoral immune response" NARROW [] +synonym: "stimulation of humoral immune response" NARROW [] +synonym: "up regulation of humoral immune response" EXACT [] +synonym: "up-regulation of humoral immune response" EXACT [] +synonym: "upregulation of humoral immune response" EXACT [] +is_a: GO:0002920 ! regulation of humoral immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006959 ! humoral immune response +relationship: positively_regulates GO:0006959 ! humoral immune response + +[Term] +id: GO:0002923 +name: regulation of humoral immune response mediated by circulating immunoglobulin +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin." [GOC:add] +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +is_a: GO:0002920 ! regulation of humoral immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin +relationship: regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin + +[Term] +id: GO:0002924 +name: negative regulation of humoral immune response mediated by circulating immunoglobulin +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin." [GOC:add] +synonym: "down regulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +synonym: "down-regulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +synonym: "downregulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +synonym: "inhibition of humoral immune response mediated by circulating immunoglobulin" NARROW [] +is_a: GO:0002890 ! negative regulation of immunoglobulin mediated immune response +is_a: GO:0002921 ! negative regulation of humoral immune response +is_a: GO:0002923 ! regulation of humoral immune response mediated by circulating immunoglobulin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin +relationship: negatively_regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin + +[Term] +id: GO:0002925 +name: positive regulation of humoral immune response mediated by circulating immunoglobulin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin." [GOC:add] +synonym: "activation of humoral immune response mediated by circulating immunoglobulin" NARROW [] +synonym: "stimulation of humoral immune response mediated by circulating immunoglobulin" NARROW [] +synonym: "up regulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +synonym: "up-regulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +synonym: "upregulation of humoral immune response mediated by circulating immunoglobulin" EXACT [] +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +is_a: GO:0002922 ! positive regulation of humoral immune response +is_a: GO:0002923 ! regulation of humoral immune response mediated by circulating immunoglobulin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin +relationship: positively_regulates GO:0002455 ! humoral immune response mediated by circulating immunoglobulin + +[Term] +id: GO:0002926 +name: tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation +namespace: biological_process +def: "The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine." [GOC:hjd, UniPathway:UPA00988] +synonym: "mcm5 modification" EXACT [] +synonym: "mcm5s2U34 biosynthesis" EXACT [] +synonym: "tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis" EXACT [] +is_a: GO:0002098 ! tRNA wobble uridine modification +created_by: hjd +creation_date: 2012-01-17T02:50:54Z + +[Term] +id: GO:0002927 +name: archaeosine-tRNA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs." [GOC:hjd, UniPathway:UPA00393] +comment: Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine. +is_a: GO:0006400 ! tRNA modification +is_a: GO:0009058 ! biosynthetic process +relationship: has_part GO:0002948 ! archaeosine synthase activity +relationship: has_part GO:0043867 ! 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity +created_by: hjd +creation_date: 2012-01-18T03:06:27Z + +[Term] +id: GO:0002929 +name: MECO complex +namespace: cellular_component +def: "A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II." [GOC:hjd, PMID:20508642] +synonym: "meta-coactivator complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0005671 ! Ada2/Gcn5/Ada3 transcription activator complex +relationship: has_part GO:0016592 ! mediator complex +created_by: hjd +creation_date: 2012-03-14T02:50:13Z + +[Term] +id: GO:0002930 +name: trabecular meshwork development +namespace: biological_process +def: "The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor." [PMID:20568247] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0043010 ! camera-type eye development +created_by: hjd +creation_date: 2012-04-19T04:50:06Z + +[Term] +id: GO:0002931 +name: response to ischemia +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply." [GOC:hjd] +comment: Ischemia always results in hypoxia; however, hypoxia can occur without ischemia. +is_a: GO:0006950 ! response to stress +created_by: hjd +creation_date: 2012-04-20T02:57:51Z + +[Term] +id: GO:0002932 +name: tendon sheath development +namespace: biological_process +def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0035989 ! tendon development +created_by: hjd +creation_date: 2012-04-23T02:11:22Z + +[Term] +id: GO:0002933 +name: lipid hydroxylation +namespace: biological_process +def: "The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid." [GOC:hjd, PMID:15658937] +synonym: "fatty acid hydroxylation" RELATED [] +is_a: GO:0030258 ! lipid modification +created_by: hjd +creation_date: 2012-04-24T02:26:33Z + +[Term] +id: GO:0002934 +name: desmosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm." [GOC:hjd] +is_a: GO:0045216 ! cell-cell junction organization +created_by: hjd +creation_date: 2012-05-08T02:59:08Z + +[Term] +id: GO:0002935 +name: tRNA (adenine-C2-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA." [PMID:22891362] +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity +created_by: hjd +creation_date: 2012-09-04T14:39:56Z + +[Term] +id: GO:0002936 +name: bradykinin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin." [PMID:11226291] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043043 ! peptide biosynthetic process +created_by: hjd +creation_date: 2012-10-17T14:24:24Z + +[Term] +id: GO:0002937 +name: tRNA 4-thiouridine biosynthesis +namespace: biological_process +def: "The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs." [ISBN:155581073X] +comment: In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis. +is_a: GO:0034227 ! tRNA thio-modification +created_by: hjd +creation_date: 2012-10-19T15:26:28Z + +[Term] +id: GO:0002938 +name: tRNA guanine ribose methylation +namespace: biological_process +def: "The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety." [ISBN:1555811337] +is_a: GO:0002128 ! tRNA nucleoside ribose methylation +created_by: hjd +creation_date: 2012-11-02T15:55:55Z + +[Term] +id: GO:0002939 +name: tRNA N1-guanine methylation +namespace: biological_process +def: "The process whereby a guanine in tRNA is methylated at position N1 of the guanine." [ISBN:155581073X, ISBN:1555811337] +synonym: "tRNA m1-guanine biosynthesis" RELATED [] +is_a: GO:0030488 ! tRNA methylation +created_by: hjd +creation_date: 2012-11-09T16:18:41Z + +[Term] +id: GO:0002940 +name: tRNA N2-guanine methylation +namespace: biological_process +def: "The process whereby a guanine in a tRNA is methylated at the N2 position of guanine." [ISBN:155581073X, ISBN:1555811337] +synonym: "tRNA m2-guanine biosynthesis" RELATED [] +is_a: GO:0030488 ! tRNA methylation +created_by: hjd +creation_date: 2012-11-09T16:23:41Z + +[Term] +id: GO:0002941 +name: synoviocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues." [CL:0000214, PMID:9546370] +is_a: GO:0008283 ! cell population proliferation +created_by: hjd +creation_date: 2012-11-16T14:25:45Z + +[Term] +id: GO:0002942 +name: tRNA m2,2-guanine biosynthesis +namespace: biological_process +def: "The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position." [GOC:hjd, ISBN:155581073X] +is_a: GO:0030488 ! tRNA methylation +created_by: hjd +creation_date: 2012-11-16T16:07:20Z + +[Term] +id: GO:0002943 +name: tRNA dihydrouridine synthesis +namespace: biological_process +def: "The process whereby a uridine in a transfer RNA is converted to dihydrouridine." [GOC:hjd, ISBN:155581073X] +comment: Dihydrouridine is found in numerous positions within loop I, the so-called dihydrouridine loop, of many transfer RNAs. Most often found at positions 16 and 17, but also sometimes at positions 20, 20a, and 20b. +is_a: GO:0006400 ! tRNA modification +created_by: hjd +creation_date: 2012-11-16T16:20:37Z + +[Term] +id: GO:0002944 +name: cyclin K-CDK12 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [PMID:22012619] +synonym: "CycK/Cdk12 complex" RELATED [] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: hjd +creation_date: 2012-12-05T16:09:48Z + +[Term] +id: GO:0002945 +name: cyclin K-CDK13 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [PMID:22012619] +synonym: "CycK/Cdk13 complex" RELATED [] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: hjd +creation_date: 2012-12-05T16:13:28Z + +[Term] +id: GO:0002946 +name: tRNA C5-cytosine methylation +namespace: biological_process +def: "The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine." [ISBN:155581073X] +synonym: "tRNA 5-methylcytosine biosynthesis" RELATED [] +is_a: GO:0030488 ! tRNA methylation +created_by: hjd +creation_date: 2012-12-07T14:23:13Z + +[Term] +id: GO:0002947 +name: tumor necrosis factor receptor superfamily complex +namespace: cellular_component +def: "A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily." [GOC:krc] +synonym: "TNF receptor superfamily complex" RELATED [] +is_a: GO:0043235 ! receptor complex +created_by: hjd +creation_date: 2012-12-20T13:26:39Z + +[Term] +id: GO:0002948 +name: archaeosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA." [PMID:20129918, Wikipedia:Archaeosine_synthase] +synonym: "ArcS" RELATED [] +synonym: "glutamine:preQ0-tRNA amidinotransferase" RELATED [] +xref: EC:2.6.1.97 +is_a: GO:0015067 ! amidinotransferase activity +created_by: hjd +creation_date: 2014-08-11T10:33:59Z + +[Term] +id: GO:0002949 +name: tRNA threonylcarbamoyladenosine modification +namespace: biological_process +alt_id: GO:0070526 +def: "The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base)." [GO:0070526, GOC:imk, GOC:mah, PMID:19287007, PMID:21183954, PMID:23258706] +synonym: "t6A biosynthesis" EXACT [PMID:19287007] +synonym: "t6A biosynthetic process" EXACT [PMID:19287007] +synonym: "t6A tRNA modification" EXACT [] +synonym: "threonylcarbamoyladenosine anabolism" EXACT [GOC:mah] +synonym: "threonylcarbamoyladenosine biosynthesis" EXACT [GOC:mah] +synonym: "threonylcarbamoyladenosine biosynthetic process" EXACT [] +synonym: "threonylcarbamoyladenosine formation" EXACT [GOC:mah] +synonym: "threonylcarbamoyladenosine synthesis" EXACT [GOC:mah] +is_a: GO:0006400 ! tRNA modification +is_a: GO:0070525 ! tRNA threonylcarbamoyladenosine metabolic process +created_by: hjd +creation_date: 2014-09-19T10:15:27Z + +[Term] +id: GO:0002950 +name: ceramide phosphoethanolamine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine." [EC:2.7.8.n3, PMID:25667419] +xref: Reactome:R-HSA-8959462 "SAMD8 transforms PE and CERA to CPE" +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: hjd +creation_date: 2016-08-16T13:41:21Z + +[Term] +id: GO:0002951 +name: leukotriene-C(4) hydrolase +namespace: molecular_function +def: "Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate." [EC:3.4.19.14, PMID:9774450] +comment: The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione. +is_a: GO:0070122 ! isopeptidase activity + +[Term] +id: GO:0002952 +name: (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione." [EC:5.3.1.32] +synonym: "phospho-AI-2 isomerase activity" RELATED [] +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0002953 +name: 5'-deoxynucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate." [EC:3.1.3.89] +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0003001 +name: obsolete generation of a signal involved in cell-cell signaling +namespace: biological_process +def: "OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal." [GOC:dph] +comment: This term was made obsolete because biosynthesis of a signal occurs before the start of cell-cell signaling. +synonym: "formation of a signal" BROAD [] +synonym: "generation of a signal involved in cell-cell signaling" EXACT [] +synonym: "generation of a signal involved in cell-cell signalling" EXACT [] +synonym: "signal generation" BROAD [] +is_obsolete: true +consider: GO:0007267 +consider: GO:0010496 +consider: GO:0023061 +consider: GO:0031130 + +[Term] +id: GO:0003002 +name: regionalization +namespace: biological_process +def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete] +synonym: "pattern formation" RELATED [GOC:dph] +is_a: GO:0007389 ! pattern specification process + +[Term] +id: GO:0003003 +name: follicular fluid formation in ovarian follicle antrum involved in fused antrum stage +namespace: biological_process +def: "The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis." [GOC:dph, GOC:isa_complete] +synonym: "follicular fluid formation in ovarian follicle antrum during fused antrum stage" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: part_of GO:0048165 ! fused antrum stage +relationship: part_of GO:0048165 ! fused antrum stage + +[Term] +id: GO:0003004 +name: follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage +namespace: biological_process +def: "The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete] +synonym: "follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: part_of GO:0048164 ! distinct antral spaces stage +relationship: part_of GO:0048164 ! distinct antral spaces stage + +[Term] +id: GO:0003005 +name: follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage +namespace: biological_process +def: "The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis." [GOC:dph, GOC:isa_complete] +synonym: "follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: GO:0001548 ! follicular fluid formation in ovarian follicle antrum +intersection_of: part_of GO:0048163 ! scattered antral spaces stage +relationship: part_of GO:0048163 ! scattered antral spaces stage + +[Term] +id: GO:0003006 +name: developmental process involved in reproduction +namespace: biological_process +def: "A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete] +synonym: "puberty" NARROW [GOC:dph] +synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022414 ! reproductive process +is_a: GO:0032502 ! developmental process +intersection_of: GO:0032502 ! developmental process +intersection_of: part_of GO:0000003 ! reproduction + +[Term] +id: GO:0003007 +name: heart morphogenesis +namespace: biological_process +def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete] +synonym: "cardiac morphogenesis" RELATED [] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0003008 +name: system process +namespace: biological_process +def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio] +synonym: "organ system process" EXACT [] +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0003009 +name: skeletal muscle contraction +namespace: biological_process +def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle] +is_a: GO:0006941 ! striated muscle contraction +relationship: part_of GO:0050881 ! musculoskeletal movement + +[Term] +id: GO:0003010 +name: voluntary skeletal muscle contraction +namespace: biological_process +def: "A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control." [GOC:mtg_cardio, GOC:mtg_muscle] +is_a: GO:0003009 ! skeletal muscle contraction + +[Term] +id: GO:0003011 +name: involuntary skeletal muscle contraction +namespace: biological_process +def: "A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control." [GOC:mtg_cardio, GOC:mtg_muscle] +is_a: GO:0003009 ! skeletal muscle contraction + +[Term] +id: GO:0003012 +name: muscle system process +namespace: biological_process +def: "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio] +synonym: "muscle physiological process" RELATED [] +is_a: GO:0003008 ! system process + +[Term] +id: GO:0003013 +name: circulatory system process +namespace: biological_process +def: "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio] +subset: goslim_chembl +subset: goslim_generic +xref: Wikipedia:Circulatory_system +is_a: GO:0003008 ! system process + +[Term] +id: GO:0003014 +name: renal system process +namespace: biological_process +def: "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10] +synonym: "excretory system process" EXACT [] +synonym: "kidney system process" RELATED [] +is_a: GO:0003008 ! system process + +[Term] +id: GO:0003015 +name: heart process +namespace: biological_process +def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio] +synonym: "cardiac process" RELATED [] +is_a: GO:0003013 ! circulatory system process + +[Term] +id: GO:0003016 +name: respiratory system process +namespace: biological_process +alt_id: GO:0010802 +def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "respiratory gaseous exchange" EXACT [] +is_a: GO:0003008 ! system process +relationship: part_of GO:0007585 ! respiratory gaseous exchange by respiratory system + +[Term] +id: GO:0003017 +name: lymph circulation +namespace: biological_process +def: "The flow of lymph through the body of an animal." [GOC:mtg_cardio] +is_a: GO:0003013 ! circulatory system process + +[Term] +id: GO:0003018 +name: vascular process in circulatory system +namespace: biological_process +def: "A circulatory process that occurs at the level of the vasculature." [GOC:mtg_cardio] +synonym: "vasculature process" EXACT [] +is_a: GO:0003013 ! circulatory system process + +[Term] +id: GO:0003019 +name: central nervous system control of baroreceptor feedback +namespace: biological_process +def: "The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris." [GOC:mtg_cardio, ISBN:0323031951] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0001978 ! regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback + +[Term] +id: GO:0003020 +name: detection of reduced oxygen by chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies." [GOC:mtg_cardio, ISBN:0323031951] +synonym: "detection of reduced oxygen by chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0070483 ! detection of hypoxia +relationship: part_of GO:0002007 ! detection of hypoxic conditions in blood by chemoreceptor signaling + +[Term] +id: GO:0003021 +name: detection of increased carbon dioxide by chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies." [GOC:mtg_cardio, ISBN:0323031951] +synonym: "detection of increased carbon dioxide by chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003031 ! detection of carbon dioxide +relationship: part_of GO:0002007 ! detection of hypoxic conditions in blood by chemoreceptor signaling + +[Term] +id: GO:0003022 +name: detection of pH by chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors." [GOC:mtg_cardio, ISBN:0323031951] +synonym: "detection of pH by chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003030 ! detection of hydrogen ion + +[Term] +id: GO:0003023 +name: baroreceptor detection of increased arterial stretch +namespace: biological_process +def: "The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal." [GOC:mtg_cardio] +is_a: GO:0001981 ! baroreceptor detection of arterial stretch +relationship: part_of GO:0001983 ! baroreceptor response to increased systemic arterial blood pressure + +[Term] +id: GO:0003024 +name: baroreceptor detection of decreased arterial stretch +namespace: biological_process +def: "The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal." [GOC:mtg_cardio] +is_a: GO:0001981 ! baroreceptor detection of arterial stretch +relationship: part_of GO:0001982 ! baroreceptor response to decreased systemic arterial blood pressure + +[Term] +id: GO:0003025 +name: regulation of systemic arterial blood pressure by baroreceptor feedback +namespace: biological_process +def: "The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "baroreceptor regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure + +[Term] +id: GO:0003026 +name: regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback +namespace: biological_process +def: "The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "aortic arch baroreceptor control of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +relationship: part_of GO:0003025 ! regulation of systemic arterial blood pressure by baroreceptor feedback + +[Term] +id: GO:0003027 +name: regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "carotid body chemoreceptor regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +synonym: "carotid body chemoreceptor response to lowering of systemic arterial blood pressure" EXACT [GOC:dph] +synonym: "regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling" EXACT [GOC:mah] +synonym: "vagal reflex" BROAD [] +is_a: GO:0001979 ! regulation of systemic arterial blood pressure by chemoreceptor signaling + +[Term] +id: GO:0003028 +name: regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "aortic body chemoreceptor regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +synonym: "aortic body chemoreceptor response to lowering of systemic arterial blood pressure" EXACT [GOC:dph] +synonym: "regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0001979 ! regulation of systemic arterial blood pressure by chemoreceptor signaling + +[Term] +id: GO:0003029 +name: detection of hypoxic conditions in blood by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies." [GOC:mtg_cardio] +synonym: "detection of hypoxic conditions in blood by carotid body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0002007 ! detection of hypoxic conditions in blood by chemoreceptor signaling +relationship: part_of GO:0003027 ! regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling + +[Term] +id: GO:0003030 +name: detection of hydrogen ion +namespace: biological_process +def: "The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0003031 +name: detection of carbon dioxide +namespace: biological_process +def: "The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0003032 +name: detection of oxygen +namespace: biological_process +def: "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0070482 ! response to oxygen levels + +[Term] +id: GO:0003033 +name: detection of hypoxic conditions in blood by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies." [GOC:mtg_cardio] +synonym: "detection of hypoxic conditions in blood by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0002007 ! detection of hypoxic conditions in blood by chemoreceptor signaling +relationship: part_of GO:0003028 ! regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling + +[Term] +id: GO:0003034 +name: detection of increased carbon dioxide by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body." [GOC:mtg_cardio] +synonym: "detection of increased carbon dioxide by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003021 ! detection of increased carbon dioxide by chemoreceptor signaling +relationship: part_of GO:0003033 ! detection of hypoxic conditions in blood by aortic body chemoreceptor signaling + +[Term] +id: GO:0003035 +name: detection of increased carbon dioxide by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body." [GOC:mtg_cardio] +synonym: "detection of increased carbon dioxide by carotid body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003021 ! detection of increased carbon dioxide by chemoreceptor signaling +relationship: part_of GO:0003029 ! detection of hypoxic conditions in blood by carotid body chemoreceptor signaling + +[Term] +id: GO:0003036 +name: detection of pH by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body." [GOC:mtg_cardio] +synonym: "detection of pH by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003022 ! detection of pH by chemoreceptor signaling +relationship: part_of GO:0003033 ! detection of hypoxic conditions in blood by aortic body chemoreceptor signaling + +[Term] +id: GO:0003037 +name: detection of pH by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body." [GOC:mtg_cardio] +synonym: "detection of pH by carotid body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003022 ! detection of pH by chemoreceptor signaling +relationship: part_of GO:0003029 ! detection of hypoxic conditions in blood by carotid body chemoreceptor signaling + +[Term] +id: GO:0003038 +name: detection of reduced oxygen by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body." [GOC:mtg_cardio] +synonym: "detection of reduced oxygen by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003020 ! detection of reduced oxygen by chemoreceptor signaling +relationship: part_of GO:0003033 ! detection of hypoxic conditions in blood by aortic body chemoreceptor signaling + +[Term] +id: GO:0003039 +name: detection of reduced oxygen by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body." [GOC:mtg_cardio] +synonym: "detection of reduced oxygen by carotid body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0003020 ! detection of reduced oxygen by chemoreceptor signaling +relationship: part_of GO:0003029 ! detection of hypoxic conditions in blood by carotid body chemoreceptor signaling + +[Term] +id: GO:0003040 +name: excitation of vasomotor center by aortic body chemoreceptor signaling +namespace: biological_process +def: "The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure." [GOC:mtg_cardio] +synonym: "excitation of vasomotor center by aortic body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0002008 ! excitation of vasomotor center by chemoreceptor signaling +relationship: part_of GO:0003028 ! regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling + +[Term] +id: GO:0003041 +name: excitation of vasomotor center by carotid body chemoreceptor signaling +namespace: biological_process +def: "The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure." [GOC:mtg_cardio] +synonym: "excitation of vasomotor center by carotid body chemoreceptor signalling" EXACT [GOC:mah] +is_a: GO:0002008 ! excitation of vasomotor center by chemoreceptor signaling +relationship: part_of GO:0003027 ! regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling + +[Term] +id: GO:0003042 +name: vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure +namespace: biological_process +def: "A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [ISBN:0323031951] +synonym: "vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure" RELATED [GOC:dph] +is_a: GO:0002012 ! vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure +relationship: part_of GO:0003027 ! regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling + +[Term] +id: GO:0003043 +name: vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure +namespace: biological_process +def: "A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure." [GOC:mtg_cardio] +synonym: "vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure" RELATED [GOC:dph] +is_a: GO:0002012 ! vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure +relationship: part_of GO:0003028 ! regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling + +[Term] +id: GO:0003044 +name: regulation of systemic arterial blood pressure mediated by a chemical signal +namespace: biological_process +def: "The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine." [GOC:mtg_cardio] +synonym: "blood pressure regulation mediated by a chemical signal" EXACT [] +is_a: GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0003045 +name: regulation of systemic arterial blood pressure by physical factors +namespace: biological_process +def: "The regulation of blood pressure mediated by detection of forces within the circulatory system." [GOC:mtg_cardio] +synonym: "blood pressure regulation by physical factors" EXACT [] +is_a: GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0003046 +name: regulation of systemic arterial blood pressure by stress relaxation +namespace: biological_process +def: "The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure regulation by stress relaxation" EXACT [] +is_a: GO:0003045 ! regulation of systemic arterial blood pressure by physical factors +is_a: GO:0003085 ! negative regulation of systemic arterial blood pressure + +[Term] +id: GO:0003047 +name: regulation of systemic arterial blood pressure by epinephrine +namespace: biological_process +def: "The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine." [GOC:mtg_cardio] +synonym: "blood pressure regulation by epinephrine" RELATED [] +synonym: "regulation of blood pressure by adrenaline" EXACT [] +is_a: GO:0003044 ! regulation of systemic arterial blood pressure mediated by a chemical signal +relationship: part_of GO:0001993 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine + +[Term] +id: GO:0003048 +name: regulation of systemic arterial blood pressure by norepinephrine +namespace: biological_process +def: "The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine." [GOC:mtg_cardio] +synonym: "blood pressure regulation by norepinephrine" RELATED [] +synonym: "regulation of blood pressure by noradrenaline" EXACT [] +is_a: GO:0003044 ! regulation of systemic arterial blood pressure mediated by a chemical signal +relationship: part_of GO:0001993 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine + +[Term] +id: GO:0003049 +name: regulation of systemic arterial blood pressure by capillary fluid shift +namespace: biological_process +def: "The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment." [GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure regulation by capillary fluid shift" EXACT [] +is_a: GO:0003045 ! regulation of systemic arterial blood pressure by physical factors + +[Term] +id: GO:0003050 +name: regulation of systemic arterial blood pressure by atrial natriuretic peptide +namespace: biological_process +def: "The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide." [GOC:mtg_cardio] +synonym: "blood pressure regulation by ANP" RELATED [GOC:mtg_cardio] +synonym: "blood pressure regulation by atrial natriuretic peptide" EXACT [] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone + +[Term] +id: GO:0003051 +name: angiotensin-mediated drinking behavior +namespace: biological_process +def: "The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst." [GOC:mtg_cardio] +synonym: "angiotensin mediated drinking behavior" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042756 ! drinking behavior +relationship: part_of GO:0002035 ! brain renin-angiotensin system + +[Term] +id: GO:0003052 +name: circadian regulation of systemic arterial blood pressure +namespace: biological_process +def: "Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours." [GOC:mtg_cardio, GOC:rl] +is_a: GO:0003073 ! regulation of systemic arterial blood pressure +is_a: GO:0007623 ! circadian rhythm + +[Term] +id: GO:0003053 +name: circadian regulation of heart rate +namespace: biological_process +def: "Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours." [GOC:mtg_cardio, GOC:rl] +synonym: "circadian regulation of heart contraction rate" RELATED [] +is_a: GO:0002027 ! regulation of heart rate +is_a: GO:0007623 ! circadian rhythm +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0003054 +name: circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus +namespace: biological_process +def: "The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours." [GOC:mtg_cardio, GOC:rl] +synonym: "master pacemaker clock regulation of blood pressure" EXACT [] +synonym: "SCN regulation of blood pressure" EXACT [] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +is_a: GO:0003052 ! circadian regulation of systemic arterial blood pressure + +[Term] +id: GO:0003055 +name: circadian regulation of heart rate by the suprachiasmatic nucleus +namespace: biological_process +def: "The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours." [GOC:mtg_cardio, GOC:rl] +synonym: "circadian regulation of heart contraction rate by the suprachiasmatic nucleus" RELATED [] +synonym: "master pacemaker clock regulation of heart rate" EXACT [] +synonym: "SCN regulation of heart rate" EXACT [] +is_a: GO:0003053 ! circadian regulation of heart rate + +[Term] +id: GO:0003056 +name: regulation of vascular smooth muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of vascular smooth muscle contraction." [GOC:mtg_cardio, GOC:mtg_sensu, GOC:rl] +is_a: GO:0006940 ! regulation of smooth muscle contraction +is_a: GO:0019229 ! regulation of vasoconstriction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014829 ! vascular smooth muscle contraction +relationship: regulates GO:0014829 ! vascular smooth muscle contraction + +[Term] +id: GO:0003057 +name: regulation of the force of heart contraction by chemical signal +namespace: biological_process +def: "The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine." [GOC:mtg_cardio, GOC:rl] +synonym: "chemical cardiac inotropy" EXACT [] +synonym: "regulation of the force of heart muscle contraction by chemical signal" RELATED [] +is_a: GO:0002026 ! regulation of the force of heart contraction + +[Term] +id: GO:0003058 +name: hormonal regulation of the force of heart contraction +namespace: biological_process +def: "The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." [GOC:mtg_cardio, GOC:rl] +synonym: "hormonal cardiac inotropy" EXACT [] +synonym: "hormonal regulation of the force of heart muscle contraction" RELATED [] +is_a: GO:0003057 ! regulation of the force of heart contraction by chemical signal + +[Term] +id: GO:0003059 +name: positive regulation of the force of heart contraction by epinephrine +namespace: biological_process +def: "The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction." [GOC:mtg_cardio, GOC:rl] +synonym: "adrenaline cardiac inotropy" EXACT [] +synonym: "adrenaline regulation of the strength of heart muscle contraction" EXACT [] +synonym: "epinephrine cardiac inotropy" EXACT [] +synonym: "increased force of heart contraction by epinephrine" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of heart contraction by adrenaline" RELATED [] +synonym: "positive regulation of heart contraction by epinephrine" RELATED [] +is_a: GO:0003099 ! positive regulation of the force of heart contraction by chemical signal +relationship: part_of GO:0001997 ! positive regulation of the force of heart contraction by epinephrine-norepinephrine + +[Term] +id: GO:0003060 +name: negative regulation of the force of heart contraction by acetylcholine +namespace: biological_process +def: "The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction." [GOC:mtg_cardio, GOC:rl] +synonym: "decreased force of heart contraction by acetylcholine" EXACT [] +is_a: GO:0003108 ! negative regulation of the force of heart contraction by chemical signal +relationship: part_of GO:0003068 ! regulation of systemic arterial blood pressure by acetylcholine + +[Term] +id: GO:0003061 +name: positive regulation of the force of heart contraction by norepinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction." [GOC:mtg_cardio, GOC:rl] +synonym: "increased force of heart contraction by adrenaline" RELATED [] +synonym: "increased force of heart contraction by norepinephrine" EXACT [] +synonym: "noradrenaline cardiac inotropy" EXACT [] +synonym: "noradrenaline regulation of the strength of heart muscle contraction" EXACT [] +synonym: "norepinephrine cardiac inotropy" EXACT [] +synonym: "positive regulation of heart contraction by adrenaline" RELATED [] +synonym: "positive regulation of heart contraction by norepinephrine" RELATED [] +is_a: GO:0003099 ! positive regulation of the force of heart contraction by chemical signal +relationship: part_of GO:0001997 ! positive regulation of the force of heart contraction by epinephrine-norepinephrine + +[Term] +id: GO:0003062 +name: regulation of heart rate by chemical signal +namespace: biological_process +def: "The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine." [GOC:dph, GOC:mtg_cardio, GOC:rl, GOC:tb] +synonym: "chemical cardiac chronotropy" EXACT [] +synonym: "chemical signal regulation of heart contraction rate" RELATED [] +synonym: "chemical signal regulation of heart rate" EXACT [GOC:dph, GOC:tb] +is_a: GO:0002027 ! regulation of heart rate + +[Term] +id: GO:0003063 +name: negative regulation of heart rate by acetylcholine +namespace: biological_process +def: "The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction." [GOC:mtg_cardio, GOC:rl] +synonym: "negative regulation of heart contraction rate by acetylcholine" RELATED [] +is_a: GO:0003062 ! regulation of heart rate by chemical signal +is_a: GO:0010459 ! negative regulation of heart rate +relationship: part_of GO:0003068 ! regulation of systemic arterial blood pressure by acetylcholine + +[Term] +id: GO:0003064 +name: regulation of heart rate by hormone +namespace: biological_process +def: "The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." [GOC:mtg_cardio, GOC:rl] +synonym: "hormonal cardiac chronotropy" EXACT [] +synonym: "regulation of the rate of heart contraction by hormone" EXACT [] +is_a: GO:0003062 ! regulation of heart rate by chemical signal + +[Term] +id: GO:0003065 +name: positive regulation of heart rate by epinephrine +namespace: biological_process +def: "The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction." [GOC:mtg_cardio, GOC:rl] +synonym: "adrenaline cardiac chronotropy" EXACT [] +synonym: "adrenaline regulation of the rate of heart muscle contraction" EXACT [] +synonym: "epinephrine cardiac chronotropy" EXACT [] +synonym: "positive regulation of heart contraction rate by epinephrine" RELATED [] +synonym: "positive regulation of heart rate by adrenaline" RELATED [] +is_a: GO:0003062 ! regulation of heart rate by chemical signal +is_a: GO:0010460 ! positive regulation of heart rate +relationship: part_of GO:0001996 ! positive regulation of heart rate by epinephrine-norepinephrine + +[Term] +id: GO:0003066 +name: positive regulation of heart rate by norepinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction." [GOC:mtg_cardio, GOC:rl] +synonym: "noradrenaline cardiac chronotropy" EXACT [] +synonym: "noradrenaline regulation of the rate of heart muscle contraction" EXACT [] +synonym: "norepinephrine cardiac chronotropy" EXACT [] +synonym: "positive regulation of heart contraction rate by norepinephrine" RELATED [] +synonym: "positive regulation of heart rate by adrenaline" EXACT [] +is_a: GO:0003062 ! regulation of heart rate by chemical signal +is_a: GO:0010460 ! positive regulation of heart rate +relationship: part_of GO:0001996 ! positive regulation of heart rate by epinephrine-norepinephrine + +[Term] +id: GO:0003067 +name: circadian regulation of systemic arterial blood pressure by hormone +namespace: biological_process +def: "The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." [GOC:mtg_cardio] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone +relationship: part_of GO:0003052 ! circadian regulation of systemic arterial blood pressure + +[Term] +id: GO:0003068 +name: regulation of systemic arterial blood pressure by acetylcholine +namespace: biological_process +def: "The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter." [GOC:mtg_cardio, GOC:rl] +synonym: "blood pressure regulation by acetylcholine" EXACT [] +is_a: GO:0003070 ! regulation of systemic arterial blood pressure by neurotransmitter + +[Term] +id: GO:0003069 +name: acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure." [GOC:mtg_cardio, GOC:rl] +synonym: "vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure" EXACT [] +is_a: GO:0003085 ! negative regulation of systemic arterial blood pressure +is_a: GO:0042311 ! vasodilation +relationship: part_of GO:0003068 ! regulation of systemic arterial blood pressure by acetylcholine + +[Term] +id: GO:0003070 +name: regulation of systemic arterial blood pressure by neurotransmitter +namespace: biological_process +def: "The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:mtg_cardio] +is_a: GO:0001976 ! nervous system process involved in regulation of systemic arterial blood pressure +is_a: GO:0003044 ! regulation of systemic arterial blood pressure mediated by a chemical signal + +[Term] +id: GO:0003071 +name: renal system process involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "renal control of blood pressure" EXACT [] +synonym: "renal regulation of systemic arterial blood pressure" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003014 ! renal system process +intersection_of: GO:0003014 ! renal system process +intersection_of: part_of GO:0003073 ! regulation of systemic arterial blood pressure +relationship: part_of GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0003072 +name: renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature." [GOC:mtg_cardio] +synonym: "regulation of systemic arterial blood pressure by renal control of peripheral vascular resistence" EXACT [GOC:dph, GOC:tb] +synonym: "renal regulation of systemic arterial blood pressure by control of peripheral vascular resistence" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure + +[Term] +id: GO:0003073 +name: regulation of systemic arterial blood pressure +namespace: biological_process +def: "The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." [GOC:mtg_cardio] +is_a: GO:0008217 ! regulation of blood pressure + +[Term] +id: GO:0003074 +name: obsolete regulation of diuresis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "regulation of diuresis" EXACT [] +is_obsolete: true +consider: GO:0035809 + +[Term] +id: GO:0003075 +name: renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure +namespace: biological_process +def: "The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system." [GOC:mtg_cardio] +synonym: "renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003072 ! renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure + +[Term] +id: GO:0003077 +name: obsolete negative regulation of diuresis +namespace: biological_process +def: "OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "negative regulation of diuresis" EXACT [] +is_obsolete: true +consider: GO:0035811 + +[Term] +id: GO:0003078 +name: obsolete regulation of natriuresis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion." [GOC:mah] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "regulation of natriuresis" EXACT [] +is_obsolete: true +consider: GO:0035813 + +[Term] +id: GO:0003079 +name: obsolete positive regulation of natriuresis +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of natriuresis." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "positive regulation of natriuresis" EXACT [] +is_obsolete: true +consider: GO:0035815 + +[Term] +id: GO:0003080 +name: obsolete negative regulation of natriuresis +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion." [GOC:mah] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "negative regulation of natriuresis" EXACT [] +is_obsolete: true +consider: GO:0035814 + +[Term] +id: GO:0003081 +name: regulation of systemic arterial blood pressure by renin-angiotensin +namespace: biological_process +def: "The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system." [GOC:mtg_cardio] +synonym: "blood pressure regulation by renin-angiotensin" EXACT [] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone + +[Term] +id: GO:0003082 +name: obsolete positive regulation of renal output by angiotensin +namespace: biological_process +def: "OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney." [GOC:dph, GOC:mtg_cardio, GOC:tb] +comment: This term was made obsolete because the term is misleading. +synonym: "angiotensin mediated positive regulation of renal output" EXACT [GOC:dph, GOC:tb] +synonym: "angiotensin-mediated positive regulation of renal output" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of renal output by angiotensin" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003083 +name: negative regulation of renal output by angiotensin +namespace: biological_process +def: "The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney." [GOC:dph, GOC:mtg_cardio, GOC:tb] +synonym: "angiotensin mediated negative regulation of renal output" EXACT [GOC:dph, GOC:tb] +synonym: "angiotensin-mediated negative regulation of renal output" EXACT [GOC:dph, GOC:tb] +is_a: GO:0002019 ! regulation of renal output by angiotensin +is_a: GO:0003084 ! positive regulation of systemic arterial blood pressure + +[Term] +id: GO:0003084 +name: positive regulation of systemic arterial blood pressure +namespace: biological_process +def: "The process that increases the force with which blood travels through the systemic arterial circulatory system." [GOC:mtg_cardio] +is_a: GO:0045777 ! positive regulation of blood pressure +relationship: part_of GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0003085 +name: negative regulation of systemic arterial blood pressure +namespace: biological_process +def: "The process that reduces the force with which blood travels through the systemic arterial circulatory system." [GOC:mtg_cardio] +is_a: GO:0045776 ! negative regulation of blood pressure +relationship: part_of GO:0003073 ! regulation of systemic arterial blood pressure + +[Term] +id: GO:0003086 +name: regulation of systemic arterial blood pressure by local renal renin-angiotensin +namespace: biological_process +def: "The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen." [GOC:mtg_cardio] +is_a: GO:0003081 ! regulation of systemic arterial blood pressure by renin-angiotensin + +[Term] +id: GO:0003087 +name: positive regulation of the force of heart contraction by neuronal epinephrine +namespace: biological_process +def: "The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by epinephrine released from the nerve endings" EXACT [] +synonym: "increased force of heart contraction by neuronal adrenaline" RELATED [] +synonym: "increased force of heart contraction by neuronal epinephrine" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of heart contraction by adrenaline" RELATED [] +synonym: "positive regulation of heart contraction by neuronal epinephrine" RELATED [] +is_a: GO:0003059 ! positive regulation of the force of heart contraction by epinephrine +relationship: part_of GO:0003090 ! positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine + +[Term] +id: GO:0003088 +name: positive regulation of the force of heart contraction by circulating epinephrine +namespace: biological_process +def: "The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by circulating adrenaline" RELATED [] +synonym: "increased force of heart contraction by epinephrine in the bloodstream" EXACT [] +synonym: "positive regulation of heart contraction by circulating adrenaline" RELATED [] +synonym: "positive regulation of heart contraction by circulating epinephrine" RELATED [] +is_a: GO:0003059 ! positive regulation of the force of heart contraction by epinephrine +relationship: part_of GO:0003089 ! positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine + +[Term] +id: GO:0003089 +name: positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine +namespace: biological_process +def: "Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by circulating adrenaline-noradrenaline" EXACT [] +synonym: "increased force of heart contraction by circulating epinephrine-norepinephrine" EXACT [GOC:dph, GOC:tb] +synonym: "increased force of heart contraction by epinephrine-norepinephrine in the blood stream" EXACT [] +synonym: "positive regulation of heart contraction by circulating adrenaline-noradrenaline" RELATED [] +synonym: "positive regulation of heart contraction by circulating epinephrine-norepinephrine" RELATED [] +is_a: GO:0001997 ! positive regulation of the force of heart contraction by epinephrine-norepinephrine + +[Term] +id: GO:0003090 +name: positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine +namespace: biological_process +def: "Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by epinephrine-norepinephrine released from the nerve endings" EXACT [] +synonym: "increased force of heart contraction by neuronal adrenaline-noradrenaline" EXACT [] +synonym: "increased force of heart contraction by neuronal epinephrine-norepinephrine" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of heart contraction by adrenaline-noradrenaline" RELATED [] +synonym: "positive regulation of heart contraction by epinephrine-norepinephrine" RELATED [] +is_a: GO:0001997 ! positive regulation of the force of heart contraction by epinephrine-norepinephrine + +[Term] +id: GO:0003091 +name: renal water homeostasis +namespace: biological_process +def: "Renal process involved in the maintenance of an internal steady state of water in the body." [GOC:mtg_cardio] +synonym: "water homeostasis by the renal system" EXACT [] +is_a: GO:0003014 ! renal system process +is_a: GO:0050891 ! multicellular organismal water homeostasis + +[Term] +id: GO:0003092 +name: renal water retention +namespace: biological_process +def: "The process in which renal water excretion is decreased." [GOC:mtg_cardio] +synonym: "negative regulation of renal water excretion" EXACT [] +is_a: GO:0035811 ! negative regulation of urine volume + +[Term] +id: GO:0003093 +name: regulation of glomerular filtration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule." [GOC:mtg_cardio] +is_a: GO:0001977 ! renal system process involved in regulation of blood volume +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003094 ! glomerular filtration +relationship: regulates GO:0003094 ! glomerular filtration + +[Term] +id: GO:0003094 +name: glomerular filtration +namespace: biological_process +def: "The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein." [GOC:mtg_cardio, GOC:sart, ISBN:0721643949] +is_a: GO:0097205 ! renal filtration + +[Term] +id: GO:0003095 +name: pressure natriuresis +namespace: biological_process +def: "The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis)." [GOC:mtg_cardio] +is_a: GO:0001977 ! renal system process involved in regulation of blood volume + +[Term] +id: GO:0003096 +name: renal sodium ion transport +namespace: biological_process +def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] +is_a: GO:0003014 ! renal system process +is_a: GO:0006814 ! sodium ion transport + +[Term] +id: GO:0003097 +name: renal water transport +namespace: biological_process +def: "The directed movement of water (H2O) by the renal system." [GOC:mtg_cardio] +is_a: GO:0003014 ! renal system process +is_a: GO:0006833 ! water transport +relationship: part_of GO:0003091 ! renal water homeostasis + +[Term] +id: GO:0003098 +name: tubuloglomerular feedback +namespace: biological_process +def: "The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus." [GOC:mtg_cardio] +xref: Wikipedia:Tubuloglomerular_feedback +is_a: GO:0001977 ! renal system process involved in regulation of blood volume +relationship: part_of GO:0003093 ! regulation of glomerular filtration + +[Term] +id: GO:0003099 +name: positive regulation of the force of heart contraction by chemical signal +namespace: biological_process +def: "Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine." [GOC:mtg_cardio] +synonym: "positive regulation of the force of heart muscle contraction by chemical signal" EXACT [] +is_a: GO:0003057 ! regulation of the force of heart contraction by chemical signal +is_a: GO:0045823 ! positive regulation of heart contraction + +[Term] +id: GO:0003100 +name: regulation of systemic arterial blood pressure by endothelin +namespace: biological_process +def: "The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor." [GOC:mtg_cardio] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone + +[Term] +id: GO:0003101 +name: regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine +namespace: biological_process +def: "The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system." [GOC:mtg_cardio] +synonym: "regulation of blood pressure by circulating adrenaline-noradrenaline" RELATED [] +is_a: GO:0001990 ! regulation of systemic arterial blood pressure by hormone + +[Term] +id: GO:0003102 +name: obsolete positive regulation of diuresis by angiotensin +namespace: biological_process +def: "OBSOLETE. Any process mediated by angiotensin that increases the rate of diuresis." [GOC:dph, GOC:mtg_cardio, GOC:tb] +comment: This term was made obsolete because the term is misleading. +synonym: "angiotensin-mediated positive regulation of diuresis" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of diuresis by angiotensin" EXACT [] +is_obsolete: true +consider: GO:0035810 + +[Term] +id: GO:0003103 +name: obsolete positive regulation of diuresis +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "positive regulation of diuresis" EXACT [] +is_obsolete: true +consider: GO:0035810 + +[Term] +id: GO:0003104 +name: positive regulation of glomerular filtration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule." [GOC:mtg_cardio] +is_a: GO:0003093 ! regulation of glomerular filtration +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003094 ! glomerular filtration +relationship: positively_regulates GO:0003094 ! glomerular filtration + +[Term] +id: GO:0003105 +name: negative regulation of glomerular filtration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule." [GOC:mtg_cardio] +is_a: GO:0003093 ! regulation of glomerular filtration +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003094 ! glomerular filtration +relationship: negatively_regulates GO:0003094 ! glomerular filtration + +[Term] +id: GO:0003106 +name: negative regulation of glomerular filtration by angiotensin +namespace: biological_process +def: "The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule." [GOC:dph, GOC:mah, GOC:tb] +synonym: "angiotensin-mediated regulation of glomerular filtration" BROAD [GOC:dph, GOC:tb] +synonym: "regulation of glomerular filtration by angiotensin" BROAD [] +is_a: GO:0003083 ! negative regulation of renal output by angiotensin +relationship: part_of GO:0003105 ! negative regulation of glomerular filtration + +[Term] +id: GO:0003107 +name: obsolete positive regulation of natriuresis by angiotensin +namespace: biological_process +def: "OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion." [GOC:dph, GOC:mtg_cardio, GOC:tb] +comment: This term was made obsolete because the term is misleading. +synonym: "angiotensin-mediated positive regulation of natriuresis" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of natriuresis by angiotensin" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003108 +name: negative regulation of the force of heart contraction by chemical signal +namespace: biological_process +def: "Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine." [GOC:mtg_cardio] +synonym: "negative regulation of the force of heart muscle contraction by chemical signal" RELATED [] +is_a: GO:0003057 ! regulation of the force of heart contraction by chemical signal +is_a: GO:0045822 ! negative regulation of heart contraction + +[Term] +id: GO:0003109 +name: positive regulation of the force of heart contraction by circulating norepinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by circulating noradrenaline" RELATED [] +synonym: "increased force of heart contraction by circulating norepinephrine" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003061 ! positive regulation of the force of heart contraction by norepinephrine + +[Term] +id: GO:0003110 +name: positive regulation of the force of heart contraction by neuronal norepinephrine +namespace: biological_process +def: "The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction." [GOC:mtg_cardio] +synonym: "increased force of heart contraction by neuronal noradrenaline" RELATED [] +synonym: "increased force of heart contraction by neuronal norepinephrine" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003061 ! positive regulation of the force of heart contraction by norepinephrine + +[Term] +id: GO:0003111 +name: positive regulation of heart rate by circulating epinephrine +namespace: biological_process +def: "The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction." [GOC:mtg_cardio] +synonym: "positive regulation of heart rate by circulating adrenaline" EXACT [] +is_a: GO:0003065 ! positive regulation of heart rate by epinephrine + +[Term] +id: GO:0003112 +name: positive regulation of heart rate by neuronal epinephrine +namespace: biological_process +def: "The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction." [GOC:mtg_cardio] +synonym: "positive regulation of heart rate by neuronal adrenaline" EXACT [] +is_a: GO:0003065 ! positive regulation of heart rate by epinephrine + +[Term] +id: GO:0003113 +name: positive regulation of heart rate by neuronal norepinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction." [GOC:mtg_cardio] +synonym: "positive regulation of heart rate by neuronal noradrenaline" EXACT [] +is_a: GO:0003066 ! positive regulation of heart rate by norepinephrine + +[Term] +id: GO:0003114 +name: positive regulation of heart rate by circulating norepinephrine +namespace: biological_process +def: "The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction." [GOC:mtg_cardio] +synonym: "positive regulation of heart rate by circulating noradrenaline" EXACT [] +is_a: GO:0003066 ! positive regulation of heart rate by norepinephrine + +[Term] +id: GO:0003115 +name: regulation of vasoconstriction by epinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings." [GOC:mtg_cardio] +is_a: GO:0019229 ! regulation of vasoconstriction + +[Term] +id: GO:0003116 +name: regulation of vasoconstriction by norepinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings." [GOC:mtg_cardio] +is_a: GO:0019229 ! regulation of vasoconstriction + +[Term] +id: GO:0003117 +name: regulation of vasoconstriction by circulating norepinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream." [GOC:mtg_cardio] +synonym: "regulation of vasoconstriction by circulating noradrenaline" EXACT [] +is_a: GO:0003116 ! regulation of vasoconstriction by norepinephrine + +[Term] +id: GO:0003118 +name: regulation of vasoconstriction by neuronal norepinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings." [GOC:mtg_cardio] +synonym: "regulation of vasoconstriction by neuronal noradrenaline" EXACT [] +is_a: GO:0003116 ! regulation of vasoconstriction by norepinephrine + +[Term] +id: GO:0003119 +name: regulation of vasoconstriction by neuronal epinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings." [GOC:mtg_cardio] +synonym: "regulation of vasoconstriction by neuronal adrenaline" EXACT [] +is_a: GO:0003115 ! regulation of vasoconstriction by epinephrine + +[Term] +id: GO:0003120 +name: regulation of vasoconstriction by circulating epinephrine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream." [GOC:mtg_cardio] +synonym: "regulation of vasoconstriction by circulating adrenaline" EXACT [] +is_a: GO:0003115 ! regulation of vasoconstriction by epinephrine + +[Term] +id: GO:0003121 +name: epinephrine-mediated vasodilation +namespace: biological_process +alt_id: GO:0003123 +alt_id: GO:0003124 +def: "A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings." [GOC:mtg_cardio] +synonym: "regulation of vasodilation by adrenaline" RELATED [] +synonym: "regulation of vasodilation by circulating adrenaline" RELATED [] +synonym: "regulation of vasodilation by circulating epinephrine" RELATED [] +synonym: "regulation of vasodilation by epinephrine" RELATED [] +synonym: "regulation of vasodilation by neuronal adrenaline" RELATED [] +synonym: "regulation of vasodilation by neuronal epinephrine" RELATED [] +is_a: GO:0042311 ! vasodilation + +[Term] +id: GO:0003122 +name: norepinephrine-mediated vasodilation +namespace: biological_process +alt_id: GO:0003125 +alt_id: GO:0003126 +def: "A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings." [GOC:mtg_cardio] +synonym: "regulation of vasodilation by circulating noradrenaline" RELATED [] +synonym: "regulation of vasodilation by circulating norepinephrine" RELATED [] +synonym: "regulation of vasodilation by neuronal noradrenaline" RELATED [] +synonym: "regulation of vasodilation by neuronal norepinephrine" RELATED [] +synonym: "regulation of vasodilation by noradrenaline" RELATED [] +synonym: "regulation of vasodilation by norepinephrine" RELATED [] +is_a: GO:0042311 ! vasodilation + +[Term] +id: GO:0003127 +name: detection of nodal flow +namespace: biological_process +def: "The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry." [GOC:mtg_heart] +is_a: GO:0009726 ! detection of endogenous stimulus +relationship: part_of GO:0007368 ! determination of left/right symmetry +created_by: tb +creation_date: 2009-09-22T02:45:48Z + +[Term] +id: GO:0003128 +name: heart field specification +namespace: biological_process +def: "The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop." [GOC:mtg_heart] +is_a: GO:0010092 ! specification of animal organ identity +relationship: part_of GO:0060914 ! heart formation +created_by: tb +creation_date: 2009-09-22T02:56:05Z + +[Term] +id: GO:0003129 +name: heart induction +namespace: biological_process +def: "The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart." [GOC:mtg_heart] +is_a: GO:0001759 ! organ induction +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0001759 ! organ induction +intersection_of: positively_regulates GO:0003128 ! heart field specification +relationship: positively_regulates GO:0003128 ! heart field specification +created_by: tb +creation_date: 2009-09-22T02:58:41Z + +[Term] +id: GO:0003130 +name: BMP signaling pathway involved in heart induction +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction." [GOC:mtg_heart] +synonym: "BMP signalling pathway involved in heart induction" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0003129 ! heart induction +relationship: part_of GO:0003134 ! endodermal-mesodermal cell signaling involved in heart induction +created_by: tb +creation_date: 2009-09-22T03:02:00Z + +[Term] +id: GO:0003131 +name: mesodermal-endodermal cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." [GOC:mtg_heart] +synonym: "mesodermal-endodermal cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +created_by: tb +creation_date: 2009-09-22T03:07:34Z + +[Term] +id: GO:0003132 +name: mesodermal-endodermal cell signaling involved in heart induction +namespace: biological_process +def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction." [GOC:mtg_heart] +synonym: "mesodermal-endodermal cell signalling involved in heart induction" EXACT [GOC:mah] +is_a: GO:0003131 ! mesodermal-endodermal cell signaling +intersection_of: GO:0003131 ! mesodermal-endodermal cell signaling +intersection_of: part_of GO:0003129 ! heart induction +relationship: part_of GO:0003129 ! heart induction +created_by: tb +creation_date: 2009-09-22T03:08:52Z + +[Term] +id: GO:0003133 +name: endodermal-mesodermal cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart] +synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +created_by: tb +creation_date: 2009-09-22T03:10:29Z + +[Term] +id: GO:0003134 +name: endodermal-mesodermal cell signaling involved in heart induction +namespace: biological_process +def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction." [GOC:mtg_heart] +synonym: "endodermal-mesodermal cell signalling involved in heart induction" EXACT [GOC:mah] +is_a: GO:0003133 ! endodermal-mesodermal cell signaling +intersection_of: GO:0003133 ! endodermal-mesodermal cell signaling +intersection_of: part_of GO:0003129 ! heart induction +relationship: part_of GO:0003129 ! heart induction +created_by: tb +creation_date: 2009-09-22T03:11:17Z + +[Term] +id: GO:0003135 +name: fibroblast growth factor receptor signaling pathway involved in heart induction +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction." [GOC:mtg_heart] +synonym: "fibroblast growth factor receptor signalling pathway involved in heart induction" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0003129 ! heart induction +relationship: part_of GO:0003129 ! heart induction +created_by: tb +creation_date: 2009-09-22T03:17:49Z + +[Term] +id: GO:0003136 +name: negative regulation of heart induction by canonical Wnt signaling pathway +namespace: biological_process +def: "Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction." [GOC:mtg_heart, PMID:19862329] +synonym: "negative regulation of cardioblast cell fate specification by Wnt receptor signaling pathway" EXACT [GOC:dph] +synonym: "negative regulation of heart induction by canonical Wnt receptor signaling pathway" EXACT [] +synonym: "negative regulation of heart induction by canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of heart induction by canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0009997 ! negative regulation of cardioblast cell fate specification +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +is_a: GO:0100012 ! regulation of heart induction by canonical Wnt signaling pathway +is_a: GO:1901320 ! negative regulation of heart induction +created_by: tb +creation_date: 2009-09-22T03:26:17Z + +[Term] +id: GO:0003137 +name: Notch signaling pathway involved in heart induction +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction." [GOC:mtg_heart] +synonym: "Notch signalling pathway involved in heart induction" EXACT [GOC:mah] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0003129 ! heart induction +relationship: part_of GO:0003129 ! heart induction +created_by: tb +creation_date: 2009-09-22T03:28:42Z + +[Term] +id: GO:0003138 +name: primary heart field specification +namespace: biological_process +def: "The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle." [GOC:mtg_heart, GOC:rl] +synonym: "FHS specification" EXACT [GOC:rl] +synonym: "first heart field specification" EXACT [GOC:rl] +is_a: GO:0003128 ! heart field specification +created_by: tb +creation_date: 2009-09-22T03:47:24Z + +[Term] +id: GO:0003139 +name: secondary heart field specification +namespace: biological_process +def: "The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)." [GOC:mtg_heart, GOC:rl, PMID:17276708] +synonym: "anterior heart field specification" NARROW [GOC:mtg_heart] +synonym: "second heart field specification" EXACT [GOC:mtg_heart, PMID:17276708] +synonym: "SHF specification" EXACT [GOC:rl, PMID:22449840] +is_a: GO:0003128 ! heart field specification +created_by: tb +creation_date: 2009-09-22T03:47:56Z + +[Term] +id: GO:0003140 +name: determination of left/right asymmetry in lateral mesoderm +namespace: biological_process +def: "The establishment of the lateral mesoderm with respect to the left and right halves." [GOC:mtg_heart] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0048368 ! lateral mesoderm development +created_by: tb +creation_date: 2009-09-22T03:58:29Z + +[Term] +id: GO:0003141 +name: obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination." [GOC:mtg_heart] +comment: This term was made obsolete because it describes involvement of the nodal signaling pathway in lateral mesoderm left/right asymmetry. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm. +synonym: "TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "transforming growth factor beta receptor signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [] +synonym: "transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +is_obsolete: true +replaced_by: GO:1900164 +created_by: tb +creation_date: 2009-09-22T04:03:22Z + +[Term] +id: GO:0003142 +name: cardiogenic plate morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart] +synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: tb +creation_date: 2009-09-22T04:12:18Z + +[Term] +id: GO:0003143 +name: embryonic heart tube morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0035050 ! embryonic heart tube development +relationship: part_of GO:0048562 ! embryonic organ morphogenesis +created_by: tb +creation_date: 2009-09-22T04:21:17Z + +[Term] +id: GO:0003144 +name: embryonic heart tube formation +namespace: biological_process +def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] +is_a: GO:0001838 ! embryonic epithelial tube formation +relationship: part_of GO:0003143 ! embryonic heart tube morphogenesis +created_by: tb +creation_date: 2009-09-22T04:22:34Z + +[Term] +id: GO:0003145 +name: embryonic heart tube formation via epithelial folding +namespace: biological_process +def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart] +is_a: GO:0003144 ! embryonic heart tube formation +created_by: tb +creation_date: 2009-09-22T04:26:03Z + +[Term] +id: GO:0003146 +name: heart jogging +namespace: biological_process +def: "The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis." [GOC:mtg_heart, PMID:9334285] +synonym: "cardiac jogging" EXACT [GOC:mtg_heart] +is_a: GO:0003143 ! embryonic heart tube morphogenesis +relationship: part_of GO:0061371 ! determination of heart left/right asymmetry +property_value: RO:0002161 NCBITaxon:40674 +created_by: tb +creation_date: 2009-09-22T06:11:41Z + +[Term] +id: GO:0003147 +name: neural crest cell migration involved in heart formation +namespace: biological_process +def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart] +is_a: GO:0001755 ! neural crest cell migration +is_a: GO:0060974 ! cell migration involved in heart formation +intersection_of: GO:0001755 ! neural crest cell migration +intersection_of: part_of GO:0060914 ! heart formation +relationship: part_of GO:0061308 ! cardiac neural crest cell development involved in heart development +created_by: tb +creation_date: 2009-09-22T04:29:55Z + +[Term] +id: GO:0003148 +name: outflow tract septum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart] +is_a: GO:0060411 ! cardiac septum morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: tb +creation_date: 2009-09-22T07:51:01Z + +[Term] +id: GO:0003149 +name: membranous septum morphogenesis +namespace: biological_process +def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060412 ! ventricular septum morphogenesis +created_by: tb +creation_date: 2009-09-22T07:51:41Z + +[Term] +id: GO:0003150 +name: muscular septum morphogenesis +namespace: biological_process +def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart] +is_a: GO:0060415 ! muscle tissue morphogenesis +relationship: part_of GO:0060412 ! ventricular septum morphogenesis +created_by: tb +creation_date: 2009-09-22T07:53:28Z + +[Term] +id: GO:0003151 +name: outflow tract morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: tb +creation_date: 2009-09-22T07:59:24Z + +[Term] +id: GO:0003152 +name: morphogenesis of an epithelial fold involved in embryonic heart tube formation +namespace: biological_process +def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +intersection_of: GO:0060571 ! morphogenesis of an epithelial fold +intersection_of: part_of GO:0003144 ! embryonic heart tube formation +relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding +created_by: tb +creation_date: 2009-09-23T10:10:24Z + +[Term] +id: GO:0003153 +name: closure of embryonic heart tube +namespace: biological_process +def: "Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold." [GOC:mtg_heart] +is_a: GO:0060606 ! tube closure +relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding +created_by: tb +creation_date: 2009-09-23T10:14:54Z + +[Term] +id: GO:0003154 +name: BMP signaling pathway involved in determination of left/right symmetry +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry." [GOC:mtg_heart, GOC:signaling] +synonym: "BMP signaling pathway involved in determination of left/right asymmetry" EXACT [GOC:dph] +synonym: "BMP signalling pathway involved in determination of left/right symmetry" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007368 ! determination of left/right symmetry +created_by: tb +creation_date: 2009-09-24T05:34:57Z + +[Term] +id: GO:0003155 +name: BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry." [GOC:mtg_heart] +synonym: "BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [] +synonym: "BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:mah] +is_a: GO:0003154 ! BMP signaling pathway involved in determination of left/right symmetry +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0003140 ! determination of left/right asymmetry in lateral mesoderm +relationship: part_of GO:0003140 ! determination of left/right asymmetry in lateral mesoderm +created_by: tb +creation_date: 2009-09-24T05:42:17Z + +[Term] +id: GO:0003156 +name: regulation of animal organ formation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb] +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048645 ! animal organ formation +relationship: regulates GO:0048645 ! animal organ formation +created_by: tb +creation_date: 2009-09-30T11:21:09Z + +[Term] +id: GO:0003157 +name: endocardium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-01T12:42:27Z + +[Term] +id: GO:0003158 +name: endothelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] +is_a: GO:0060429 ! epithelium development +created_by: dph +creation_date: 2009-10-01T12:50:57Z + +[Term] +id: GO:0003159 +name: morphogenesis of an endothelium +namespace: biological_process +def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0003158 ! endothelium development +created_by: dph +creation_date: 2009-10-01T01:34:06Z + +[Term] +id: GO:0003160 +name: endocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003157 ! endocardium development +created_by: dph +creation_date: 2009-10-01T01:37:26Z + +[Term] +id: GO:0003161 +name: cardiac conduction system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart] +synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart] +synonym: "heart conduction system development" EXACT [GOC:mtg_heart] +is_a: GO:0048738 ! cardiac muscle tissue development +created_by: dph +creation_date: 2009-10-01T01:57:16Z + +[Term] +id: GO:0003162 +name: atrioventricular node development +namespace: biological_process +def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart] +synonym: "AV node development" EXACT [GOC:mtg_heart] +is_a: GO:0048738 ! cardiac muscle tissue development +relationship: part_of GO:0003161 ! cardiac conduction system development +created_by: dph +creation_date: 2009-10-01T02:05:13Z + +[Term] +id: GO:0003163 +name: sinoatrial node development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart] +synonym: "SA node development" EXACT [GOC:mtg_heart] +synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "sinus node development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0048738 ! cardiac muscle tissue development +relationship: part_of GO:0003161 ! cardiac conduction system development +created_by: dph +creation_date: 2009-10-01T02:06:09Z + +[Term] +id: GO:0003164 +name: His-Purkinje system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] +is_a: GO:0003229 ! ventricular cardiac muscle tissue development +relationship: part_of GO:0003161 ! cardiac conduction system development +created_by: dph +creation_date: 2009-10-01T02:07:12Z + +[Term] +id: GO:0003165 +name: Purkinje myocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +synonym: "cardiac Purkinje fiber development" EXACT [] +is_a: GO:0003229 ! ventricular cardiac muscle tissue development +relationship: part_of GO:0003164 ! His-Purkinje system development +created_by: dph +creation_date: 2009-10-01T02:07:50Z + +[Term] +id: GO:0003166 +name: bundle of His development +namespace: biological_process +def: "The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers." [GOC:mtg_heart] +synonym: "atrioventricular bundle development" EXACT [GOC:mtg_heart] +is_a: GO:0003229 ! ventricular cardiac muscle tissue development +relationship: part_of GO:0003164 ! His-Purkinje system development +created_by: dph +creation_date: 2009-10-01T02:08:43Z + +[Term] +id: GO:0003167 +name: atrioventricular bundle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers." [GOC:mtg_heart] +synonym: "AV bundle cell differentiation" EXACT [GOC:mtg_heart] +is_a: GO:0060932 ! His-Purkinje system cell differentiation +relationship: part_of GO:0003166 ! bundle of His development +created_by: dph +creation_date: 2009-10-01T02:48:23Z + +[Term] +id: GO:0003168 +name: Purkinje myocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +synonym: "cardiac Purkinje fiber cell differentiation" EXACT [] +is_a: GO:0060932 ! His-Purkinje system cell differentiation +relationship: part_of GO:0003165 ! Purkinje myocyte development +created_by: dph +creation_date: 2009-10-01T02:49:54Z + +[Term] +id: GO:0003169 +name: coronary vein morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart] +is_a: GO:0048845 ! venous blood vessel morphogenesis +is_a: GO:0060977 ! coronary vasculature morphogenesis +created_by: dph +creation_date: 2009-10-08T10:45:41Z + +[Term] +id: GO:0003170 +name: heart valve development +namespace: biological_process +def: "The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion." [GOC:mtg_heart] +synonym: "cardiac valve development" EXACT [GOC:mtg_heart] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-08T10:50:09Z + +[Term] +id: GO:0003171 +name: atrioventricular valve development +namespace: biological_process +def: "The progression of the atrioventricular valve over time, from its formation to the mature structure." [GOC:mtg_heart] +synonym: "AV valve development" EXACT [GOC:mah] +is_a: GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-08T11:14:21Z + +[Term] +id: GO:0003172 +name: sinoatrial valve development +namespace: biological_process +def: "The progression of the sinoatrial valve over time, from its formation to the mature structure." [GOC:mtg_heart] +synonym: "SA valve development" EXACT [GOC:mah] +is_a: GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-08T11:15:39Z + +[Term] +id: GO:0003173 +name: ventriculo bulbo valve development +namespace: biological_process +def: "The progression of the ventriculo bulbo valve over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-08T11:16:25Z + +[Term] +id: GO:0003174 +name: mitral valve development +namespace: biological_process +def: "The progression of the mitral valve over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003171 ! atrioventricular valve development +created_by: dph +creation_date: 2009-10-08T11:17:22Z + +[Term] +id: GO:0003175 +name: tricuspid valve development +namespace: biological_process +def: "The progression of the tricuspid valve over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003171 ! atrioventricular valve development +created_by: dph +creation_date: 2009-10-08T11:18:12Z + +[Term] +id: GO:0003176 +name: aortic valve development +namespace: biological_process +def: "The progression of the aortic valve over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:1905314 ! semi-lunar valve development +created_by: dph +creation_date: 2009-10-08T11:18:55Z + +[Term] +id: GO:0003177 +name: pulmonary valve development +namespace: biological_process +def: "The progression of the pulmonary valve over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:1905314 ! semi-lunar valve development +created_by: dph +creation_date: 2009-10-08T11:19:44Z + +[Term] +id: GO:0003178 +name: coronary sinus valve development +namespace: biological_process +def: "The progression of the valve of the coronary sinus over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-08T11:21:43Z + +[Term] +id: GO:0003179 +name: heart valve morphogenesis +namespace: biological_process +def: "The process in which the structure of a heart valve is generated and organized." [GOC:mtg_heart] +synonym: "heart valve remodeling" NARROW [GOC:vk, GOC:yaf] +synonym: "heart valve remodelling" NARROW [GOC:vk, GOC:yaf] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-08T11:23:48Z + +[Term] +id: GO:0003180 +name: aortic valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the aortic valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003176 ! aortic valve development +created_by: dph +creation_date: 2009-10-08T11:29:42Z + +[Term] +id: GO:0003181 +name: atrioventricular valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the atrioventricular valve is generated and organized." [GOC:mtg_heart] +synonym: "AV valve morphogenesis" EXACT [GOC:mah] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003171 ! atrioventricular valve development +created_by: dph +creation_date: 2009-10-08T11:31:59Z + +[Term] +id: GO:0003182 +name: coronary sinus valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the coronary sinus valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003178 ! coronary sinus valve development +created_by: dph +creation_date: 2009-10-08T11:33:31Z + +[Term] +id: GO:0003183 +name: mitral valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the mitral valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003181 ! atrioventricular valve morphogenesis +relationship: part_of GO:0003174 ! mitral valve development +created_by: dph +creation_date: 2009-10-08T12:02:01Z + +[Term] +id: GO:0003184 +name: pulmonary valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the pulmonary valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003177 ! pulmonary valve development +created_by: dph +creation_date: 2009-10-08T12:03:35Z + +[Term] +id: GO:0003185 +name: sinoatrial valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the sinoatrial valve is generated and organized." [GOC:mtg_heart] +synonym: "SA valve morphogenesis" EXACT [GOC:mah] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003172 ! sinoatrial valve development +created_by: dph +creation_date: 2009-10-08T12:04:52Z + +[Term] +id: GO:0003186 +name: tricuspid valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the tricuspid valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003181 ! atrioventricular valve morphogenesis +relationship: part_of GO:0003175 ! tricuspid valve development +created_by: dph +creation_date: 2009-10-08T12:05:45Z + +[Term] +id: GO:0003187 +name: ventriculo bulbo valve morphogenesis +namespace: biological_process +def: "The process in which the structure of the ventriculo bulbo valve is generated and organized." [GOC:mtg_heart] +is_a: GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003173 ! ventriculo bulbo valve development +created_by: dph +creation_date: 2009-10-08T12:07:00Z + +[Term] +id: GO:0003188 +name: heart valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003179 ! heart valve morphogenesis +created_by: dph +creation_date: 2009-10-08T12:20:15Z + +[Term] +id: GO:0003189 +name: aortic valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003180 ! aortic valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:05:44Z + +[Term] +id: GO:0003190 +name: atrioventricular valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +synonym: "AV valve formation" EXACT [GOC:mah] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003181 ! atrioventricular valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:07:28Z + +[Term] +id: GO:0003191 +name: coronary sinus valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003182 ! coronary sinus valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:09:04Z + +[Term] +id: GO:0003192 +name: mitral valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003190 ! atrioventricular valve formation +relationship: part_of GO:0003183 ! mitral valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:10:19Z + +[Term] +id: GO:0003193 +name: pulmonary valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003184 ! pulmonary valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:11:20Z + +[Term] +id: GO:0003194 +name: sinoatrial valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +synonym: "SA valve formation" EXACT [GOC:mah] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003185 ! sinoatrial valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:12:45Z + +[Term] +id: GO:0003195 +name: tricuspid valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003190 ! atrioventricular valve formation +relationship: part_of GO:0003186 ! tricuspid valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:14:40Z + +[Term] +id: GO:0003196 +name: ventriculo bulbo valve formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable." [GOC:mtg_heart] +is_a: GO:0003188 ! heart valve formation +relationship: part_of GO:0003187 ! ventriculo bulbo valve morphogenesis +created_by: dph +creation_date: 2009-10-08T01:16:02Z + +[Term] +id: GO:0003197 +name: endocardial cushion development +namespace: biological_process +def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-08T01:17:43Z + +[Term] +id: GO:0003198 +name: epithelial to mesenchymal transition involved in endocardial cushion formation +namespace: biological_process +def: "A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion." [GOC:mtg_heart] +is_a: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: part_of GO:0003272 ! endocardial cushion formation +relationship: part_of GO:0003272 ! endocardial cushion formation +created_by: dph +creation_date: 2009-10-08T01:27:42Z + +[Term] +id: GO:0003199 +name: endocardial cushion to mesenchymal transition involved in heart valve formation +namespace: biological_process +def: "A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve." [GOC:mtg_heart] +synonym: "endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:bf] +is_a: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: part_of GO:0003188 ! heart valve formation +relationship: part_of GO:0003188 ! heart valve formation +created_by: dph +creation_date: 2009-10-08T01:31:21Z + +[Term] +id: GO:0003200 +name: endocardial cushion to mesenchymal transition involved in heart chamber septation +namespace: biological_process +def: "A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum." [GOC:mtg_heart] +is_a: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: part_of GO:0060411 ! cardiac septum morphogenesis +relationship: part_of GO:0060411 ! cardiac septum morphogenesis +created_by: dph +creation_date: 2009-10-08T01:34:31Z + +[Term] +id: GO:0003201 +name: epithelial to mesenchymal transition involved in coronary vasculature morphogenesis +namespace: biological_process +def: "A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature." [GOC:mtg_heart] +is_a: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis +relationship: part_of GO:0060977 ! coronary vasculature morphogenesis +created_by: dph +creation_date: 2009-10-08T01:36:54Z + +[Term] +id: GO:0003202 +name: endocardial cushion to mesenchymal transition involved in cardiac skeleton development +namespace: biological_process +def: "A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton." [GOC:mtg_heart] +is_a: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: GO:0090500 ! endocardial cushion to mesenchymal transition +intersection_of: part_of GO:0003204 ! cardiac skeleton development +relationship: part_of GO:0003204 ! cardiac skeleton development +created_by: dph +creation_date: 2009-10-08T01:39:57Z + +[Term] +id: GO:0003203 +name: endocardial cushion morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] +is_a: GO:0072132 ! mesenchyme morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003197 ! endocardial cushion development +created_by: dph +creation_date: 2009-10-08T01:43:22Z + +[Term] +id: GO:0003204 +name: cardiac skeleton development +namespace: biological_process +def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart] +synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-13T09:05:04Z + +[Term] +id: GO:0003205 +name: cardiac chamber development +namespace: biological_process +def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-13T09:11:18Z + +[Term] +id: GO:0003206 +name: cardiac chamber morphogenesis +namespace: biological_process +def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] +synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T09:14:51Z + +[Term] +id: GO:0003207 +name: cardiac chamber formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] +synonym: "heart chamber formation" EXACT [GOC:mtg_heart] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003206 ! cardiac chamber morphogenesis +created_by: dph +creation_date: 2009-10-13T09:29:13Z + +[Term] +id: GO:0003208 +name: cardiac ventricle morphogenesis +namespace: biological_process +def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] +is_a: GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003231 ! cardiac ventricle development +created_by: dph +creation_date: 2009-10-13T09:38:44Z + +[Term] +id: GO:0003209 +name: cardiac atrium morphogenesis +namespace: biological_process +def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] +is_a: GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003230 ! cardiac atrium development +created_by: dph +creation_date: 2009-10-13T09:39:44Z + +[Term] +id: GO:0003210 +name: cardiac atrium formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] +is_a: GO:0003207 ! cardiac chamber formation +relationship: part_of GO:0003209 ! cardiac atrium morphogenesis +created_by: dph +creation_date: 2009-10-13T09:44:25Z + +[Term] +id: GO:0003211 +name: cardiac ventricle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] +is_a: GO:0003207 ! cardiac chamber formation +relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T09:46:27Z + +[Term] +id: GO:0003212 +name: cardiac left atrium morphogenesis +namespace: biological_process +def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart] +is_a: GO:0003209 ! cardiac atrium morphogenesis +created_by: dph +creation_date: 2009-10-13T09:48:16Z + +[Term] +id: GO:0003213 +name: cardiac right atrium morphogenesis +namespace: biological_process +def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart] +is_a: GO:0003209 ! cardiac atrium morphogenesis +created_by: dph +creation_date: 2009-10-13T09:49:03Z + +[Term] +id: GO:0003214 +name: cardiac left ventricle morphogenesis +namespace: biological_process +def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart] +is_a: GO:0003208 ! cardiac ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T09:50:08Z + +[Term] +id: GO:0003215 +name: cardiac right ventricle morphogenesis +namespace: biological_process +def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart] +is_a: GO:0003208 ! cardiac ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T09:50:57Z + +[Term] +id: GO:0003216 +name: cardiac left atrium formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart] +is_a: GO:0003210 ! cardiac atrium formation +relationship: part_of GO:0003212 ! cardiac left atrium morphogenesis +created_by: dph +creation_date: 2009-10-13T09:52:31Z + +[Term] +id: GO:0003217 +name: cardiac right atrium formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart] +is_a: GO:0003210 ! cardiac atrium formation +relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis +created_by: dph +creation_date: 2009-10-13T09:53:12Z + +[Term] +id: GO:0003218 +name: cardiac left ventricle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart] +is_a: GO:0003211 ! cardiac ventricle formation +relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T09:54:33Z + +[Term] +id: GO:0003219 +name: cardiac right ventricle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart] +is_a: GO:0003211 ! cardiac ventricle formation +relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T09:55:38Z + +[Term] +id: GO:0003220 +name: left ventricular cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] +synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis +relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T10:18:05Z + +[Term] +id: GO:0003221 +name: right ventricular cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] +synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis +relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T10:26:33Z + +[Term] +id: GO:0003222 +name: ventricular trabecula myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] +synonym: "trabecula carnea morphogenesis" RELATED [GOC:dph] +is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis +is_a: GO:0061384 ! heart trabecula morphogenesis +created_by: dph +creation_date: 2009-10-13T10:33:00Z + +[Term] +id: GO:0003223 +name: ventricular compact myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] +is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis +created_by: dph +creation_date: 2009-10-13T10:34:21Z + +[Term] +id: GO:0003224 +name: left ventricular compact myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized." [GOC:mtg_heart] +is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis +is_a: GO:0003223 ! ventricular compact myocardium morphogenesis +created_by: dph +creation_date: 2009-10-13T10:43:36Z + +[Term] +id: GO:0003225 +name: left ventricular trabecular myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart] +is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis +is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis +created_by: dph +creation_date: 2009-10-13T10:45:09Z + +[Term] +id: GO:0003226 +name: right ventricular compact myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized." [GOC:mtg_heart] +is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis +is_a: GO:0003223 ! ventricular compact myocardium morphogenesis +created_by: dph +creation_date: 2009-10-13T10:48:42Z + +[Term] +id: GO:0003227 +name: right ventricular trabecular myocardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart] +is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis +is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis +created_by: dph +creation_date: 2009-10-13T10:50:59Z + +[Term] +id: GO:0003228 +name: atrial cardiac muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart] +synonym: "atrial myocardium development" EXACT [GOC:mtg_heart] +is_a: GO:0048856 ! anatomical structure development +created_by: dph +creation_date: 2009-10-13T10:53:18Z + +[Term] +id: GO:0003229 +name: ventricular cardiac muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart] +synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart] +is_a: GO:0048738 ! cardiac muscle tissue development +created_by: dph +creation_date: 2009-10-13T10:56:01Z + +[Term] +id: GO:0003230 +name: cardiac atrium development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] +is_a: GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T11:02:07Z + +[Term] +id: GO:0003231 +name: cardiac ventricle development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] +is_a: GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T11:03:16Z + +[Term] +id: GO:0003232 +name: bulbus arteriosus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber." [GOC:mtg_heart] +is_a: GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T11:05:36Z + +[Term] +id: GO:0003233 +name: bulbus arteriosus morphogenesis +namespace: biological_process +def: "The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber." [GOC:mtg_heart] +is_a: GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003232 ! bulbus arteriosus development +created_by: dph +creation_date: 2009-10-13T11:07:30Z + +[Term] +id: GO:0003234 +name: bulbus arteriosus formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart." [GOC:mtg_heart] +is_a: GO:0003207 ! cardiac chamber formation +relationship: part_of GO:0003233 ! bulbus arteriosus morphogenesis +created_by: dph +creation_date: 2009-10-13T11:10:02Z + +[Term] +id: GO:0003235 +name: sinus venosus development +namespace: biological_process +def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] +is_a: GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T11:12:34Z + +[Term] +id: GO:0003236 +name: sinus venosus morphogenesis +namespace: biological_process +def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] +is_a: GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003235 ! sinus venosus development +created_by: dph +creation_date: 2009-10-13T11:16:52Z + +[Term] +id: GO:0003237 +name: sinus venosus formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] +is_a: GO:0003207 ! cardiac chamber formation +relationship: part_of GO:0003236 ! sinus venosus morphogenesis +created_by: dph +creation_date: 2009-10-13T11:18:34Z + +[Term] +id: GO:0003238 +name: conus arteriosus development +namespace: biological_process +def: "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] +is_a: GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-13T11:20:57Z + +[Term] +id: GO:0003239 +name: conus arteriosus morphogenesis +namespace: biological_process +def: "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] +is_a: GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003238 ! conus arteriosus development +created_by: dph +creation_date: 2009-10-13T11:25:04Z + +[Term] +id: GO:0003240 +name: conus arteriosus formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] +is_a: GO:0003207 ! cardiac chamber formation +relationship: part_of GO:0003239 ! conus arteriosus morphogenesis +created_by: dph +creation_date: 2009-10-13T11:25:47Z + +[Term] +id: GO:0003241 +name: growth involved in heart morphogenesis +namespace: biological_process +def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +intersection_of: GO:0040007 ! growth +intersection_of: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0060419 ! heart growth +created_by: dph +creation_date: 2009-10-13T11:28:46Z + +[Term] +id: GO:0003242 +name: cardiac chamber ballooning +namespace: biological_process +def: "The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping." [GOC:mtg_heart] +is_a: GO:0003241 ! growth involved in heart morphogenesis +relationship: part_of GO:0003206 ! cardiac chamber morphogenesis +created_by: dph +creation_date: 2009-10-13T11:30:30Z + +[Term] +id: GO:0003243 +name: circumferential growth involved in left ventricle morphogenesis +namespace: biological_process +def: "The morphogenetic growth in which the left ventricle grows expanding its external boundary." [GOC:mtg_heart, PMID:14709543] +is_a: GO:0003241 ! growth involved in heart morphogenesis +relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T11:33:09Z + +[Term] +id: GO:0003244 +name: radial growth involved in right ventricle morphogenesis +namespace: biological_process +def: "The morphogenic growth in which the right ventricle grows along a radial axis." [GOC:mtg_heart] +is_a: GO:0003241 ! growth involved in heart morphogenesis +relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis +created_by: dph +creation_date: 2009-10-13T11:38:23Z + +[Term] +id: GO:0003245 +name: cardiac muscle tissue growth involved in heart morphogenesis +namespace: biological_process +def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart] +is_a: GO:0003241 ! growth involved in heart morphogenesis +is_a: GO:0055017 ! cardiac muscle tissue growth +intersection_of: GO:0055017 ! cardiac muscle tissue growth +intersection_of: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis +created_by: dph +creation_date: 2009-10-13T11:44:21Z + +[Term] +id: GO:0003246 +name: embryonic cardiac muscle cell growth involved in heart morphogenesis +namespace: biological_process +def: "The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart." [GOC:mtg_heart] +synonym: "embryonic cardiac muscle physiological hypertrophy" EXACT [GOC:mtg_heart] +is_a: GO:0003241 ! growth involved in heart morphogenesis +is_a: GO:0061049 ! cell growth involved in cardiac muscle cell development +relationship: part_of GO:0003245 ! cardiac muscle tissue growth involved in heart morphogenesis +created_by: dph +creation_date: 2009-10-13T11:46:23Z + +[Term] +id: GO:0003247 +name: post-embryonic cardiac muscle cell growth involved in heart morphogenesis +namespace: biological_process +def: "The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart." [GOC:mtg_heart] +is_a: GO:0003241 ! growth involved in heart morphogenesis +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0003245 ! cardiac muscle tissue growth involved in heart morphogenesis +created_by: dph +creation_date: 2009-10-13T11:50:29Z + +[Term] +id: GO:0003248 +name: heart capillary growth +namespace: biological_process +def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart] +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0060419 ! heart growth +relationship: part_of GO:0060976 ! coronary vasculature development +created_by: dph +creation_date: 2009-10-13T11:53:12Z + +[Term] +id: GO:0003249 +name: cell proliferation involved in heart valve morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of cells that contributes to the shaping of a heart valve." [GOC:mtg_heart] +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +is_a: GO:2000793 ! cell proliferation involved in heart valve development +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003179 ! heart valve morphogenesis +created_by: dph +creation_date: 2009-10-13T01:59:19Z + +[Term] +id: GO:0003250 +name: regulation of cell proliferation involved in heart valve morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve." [GOC:mtg_heart] +is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +relationship: regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +created_by: dph +creation_date: 2009-10-13T02:03:42Z + +[Term] +id: GO:0003251 +name: positive regulation of cell proliferation involved in heart valve morphogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve." [GOC:mtg_heart] +is_a: GO:0003250 ! regulation of cell proliferation involved in heart valve morphogenesis +is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +relationship: positively_regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +created_by: dph +creation_date: 2009-10-13T02:07:20Z + +[Term] +id: GO:0003252 +name: negative regulation of cell proliferation involved in heart valve morphogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve." [GOC:mtg_heart] +is_a: GO:0003250 ! regulation of cell proliferation involved in heart valve morphogenesis +is_a: GO:2000137 ! negative regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +relationship: negatively_regulates GO:0003249 ! cell proliferation involved in heart valve morphogenesis +created_by: dph +creation_date: 2009-10-13T02:10:39Z + +[Term] +id: GO:0003253 +name: cardiac neural crest cell migration involved in outflow tract morphogenesis +namespace: biological_process +def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart] +is_a: GO:0001755 ! neural crest cell migration +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0001755 ! neural crest cell migration +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0061309 ! cardiac neural crest cell development involved in outflow tract morphogenesis +created_by: dph +creation_date: 2009-10-13T02:14:16Z + +[Term] +id: GO:0003254 +name: regulation of membrane depolarization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive." [GOC:dph, GOC:tb] +is_a: GO:0042391 ! regulation of membrane potential +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0050801 ! ion homeostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051899 ! membrane depolarization +relationship: regulates GO:0051899 ! membrane depolarization +created_by: tb +creation_date: 2009-10-14T10:54:09Z + +[Term] +id: GO:0003255 +name: endocardial precursor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate." [GOC:mtg_heart] +is_a: GO:0010002 ! cardioblast differentiation +created_by: dph +creation_date: 2009-10-15T12:09:43Z + +[Term] +id: GO:0003256 +name: regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell." [GOC:mtg_heart] +is_a: GO:1901213 ! regulation of transcription from RNA polymerase II promoter involved in heart development +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0060379 ! cardiac muscle cell myoblast differentiation +relationship: part_of GO:0060379 ! cardiac muscle cell myoblast differentiation +created_by: dph +creation_date: 2009-10-15T01:01:25Z + +[Term] +id: GO:0003257 +name: positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell." [GOC:mtg_heart] +is_a: GO:0003256 ! regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation +is_a: GO:1901228 ! positive regulation of transcription from RNA polymerase II promoter involved in heart development +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0060379 ! cardiac muscle cell myoblast differentiation +created_by: dph +creation_date: 2009-10-15T01:07:25Z + +[Term] +id: GO:0003258 +name: regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell." [GOC:mtg_heart] +is_a: GO:1901213 ! regulation of transcription from RNA polymerase II promoter involved in heart development +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0003255 ! endocardial precursor cell differentiation +relationship: part_of GO:0003255 ! endocardial precursor cell differentiation +created_by: dph +creation_date: 2009-10-15T01:10:34Z + +[Term] +id: GO:0003259 +name: cardioblast anterior-lateral migration +namespace: biological_process +def: "The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +is_a: GO:0003260 ! cardioblast migration +created_by: dph +creation_date: 2009-10-15T01:17:28Z + +[Term] +id: GO:0003260 +name: cardioblast migration +namespace: biological_process +def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +is_a: GO:0060974 ! cell migration involved in heart formation +created_by: dph +creation_date: 2009-10-15T01:52:25Z + +[Term] +id: GO:0003261 +name: cardiac muscle progenitor cell migration to the midline involved in heart field formation +namespace: biological_process +def: "The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart." [GOC:mtg_heart] +synonym: "myocardial progenitor cell midline convergence" EXACT [GOC:mtg_heart] +is_a: GO:0060975 ! cardioblast migration to the midline involved in heart field formation +created_by: dph +creation_date: 2009-10-15T01:57:55Z + +[Term] +id: GO:0003262 +name: endocardial progenitor cell migration to the midline involved in heart field formation +namespace: biological_process +def: "The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart." [GOC:mtg_heart] +is_a: GO:0060975 ! cardioblast migration to the midline involved in heart field formation +created_by: dph +creation_date: 2009-10-15T02:00:41Z + +[Term] +id: GO:0003263 +name: cardioblast proliferation +namespace: biological_process +def: "The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +relationship: part_of GO:0060914 ! heart formation +created_by: dph +creation_date: 2009-10-15T02:13:05Z + +[Term] +id: GO:0003264 +name: regulation of cardioblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +is_a: GO:0003156 ! regulation of animal organ formation +is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003263 ! cardioblast proliferation +relationship: regulates GO:0003263 ! cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:19:37Z + +[Term] +id: GO:0003265 +name: regulation of primary heart field cardioblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle." [GOC:mtg_heart, GOC:rl] +synonym: "regulation of FHF cardioblast proliferation" EXACT [GOC:rl] +synonym: "regulation of first heart field cardiac proliferation" RELATED [] +synonym: "regulation of first heart field cardioblast proliferation" EXACT [GOC:rl] +is_a: GO:0003264 ! regulation of cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:25:26Z + +[Term] +id: GO:0003266 +name: regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)." [GOC:mtg_heart, GOC:rl, PMID:17276708] +synonym: "regulation of second heart field cardioblast proliferation" EXACT [GOC:dph] +synonym: "regulation of SHF cardioblast proliferation" EXACT [GOC:rl] +is_a: GO:0003264 ! regulation of cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:26:15Z + +[Term] +id: GO:0003267 +name: canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of second heart field cardioblast proliferation" EXACT [GOC:dph] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of secondary heart field cardioblast proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation" RELATED [GOC:signaling] +is_a: GO:0044340 ! canonical Wnt signaling pathway involved in regulation of cell proliferation +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: part_of GO:0072513 ! positive regulation of secondary heart field cardioblast proliferation +relationship: part_of GO:0072513 ! positive regulation of secondary heart field cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:36:08Z + +[Term] +id: GO:0003268 +name: fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "fibroblast growth factor receptor signaling pathway involved in regulation of second heart field cardioblast cell proliferation" EXACT [GOC:dph] +synonym: "fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast cell proliferation" EXACT [GOC:bf] +synonym: "fibroblast growth factor receptor signalling pathway involved in regulation of secondary heart field cardioblast cell proliferation" EXACT [GOC:mah] +is_a: GO:0061313 ! fibroblast growth factor receptor signaling pathway involved in heart development +intersection_of: GO:0061313 ! fibroblast growth factor receptor signaling pathway involved in heart development +intersection_of: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +relationship: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:43:03Z + +[Term] +id: GO:0003269 +name: BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "BMP signaling pathway involved in regulation of second heart field cardioblast proliferation" EXACT [GOC:dph] +synonym: "BMP signalling pathway involved in regulation of secondary heart field cardioblast proliferation" EXACT [GOC:mah] +is_a: GO:0061312 ! BMP signaling pathway involved in heart development +intersection_of: GO:0061312 ! BMP signaling pathway involved in heart development +intersection_of: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +relationship: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:45:28Z + +[Term] +id: GO:0003270 +name: Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "Notch signaling pathway involved in regulation of second heart field cardioblast proliferation" RELATED [GOC:dph] +synonym: "Notch signalling pathway involved in regulation of secondary heart field cardioblast proliferation" EXACT [GOC:mah] +is_a: GO:0061314 ! Notch signaling involved in heart development +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +relationship: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:47:00Z + +[Term] +id: GO:0003271 +name: smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in regulation of second heart field cardioblast proliferation" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation" EXACT [GOC:dph] +synonym: "smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation" EXACT [GOC:bf] +synonym: "smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation" EXACT [GOC:mah] +is_a: GO:0007224 ! smoothened signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +relationship: part_of GO:0003266 ! regulation of secondary heart field cardioblast proliferation +created_by: dph +creation_date: 2009-10-15T02:48:32Z + +[Term] +id: GO:0003272 +name: endocardial cushion formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003203 ! endocardial cushion morphogenesis +created_by: dph +creation_date: 2009-10-20T08:53:19Z + +[Term] +id: GO:0003273 +name: cell migration involved in endocardial cushion formation +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0003272 ! endocardial cushion formation +relationship: part_of GO:0003272 ! endocardial cushion formation +created_by: dph +creation_date: 2009-10-20T09:08:44Z + +[Term] +id: GO:0003274 +name: endocardial cushion fusion +namespace: biological_process +def: "The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping." [GOC:mtg_heart] +is_a: GO:0061343 ! cell adhesion involved in heart morphogenesis +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis +relationship: part_of GO:0003203 ! endocardial cushion morphogenesis +created_by: dph +creation_date: 2009-10-20T09:26:32Z + +[Term] +id: GO:0003275 +name: apoptotic process involved in outflow tract morphogenesis +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart] +synonym: "apoptosis involved in outflow tract morphogenesis" NARROW [] +is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: dph +creation_date: 2009-10-20T09:30:01Z + +[Term] +id: GO:0003276 +name: apoptotic process involved in heart valve morphogenesis +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of a heart valve." [GOC:mtg_apoptosis, GOC:mtg_heart] +synonym: "apoptosis involved in heart valve morphogenesis" NARROW [] +is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0003179 ! heart valve morphogenesis +relationship: part_of GO:0003179 ! heart valve morphogenesis +created_by: dph +creation_date: 2009-10-20T09:34:29Z + +[Term] +id: GO:0003277 +name: apoptotic process involved in endocardial cushion morphogenesis +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart] +synonym: "apoptosis involved in endocardial cushion morphogenesis" NARROW [] +is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis +relationship: part_of GO:0003203 ! endocardial cushion morphogenesis +created_by: dph +creation_date: 2009-10-20T09:37:03Z + +[Term] +id: GO:0003278 +name: apoptotic process involved in heart morphogenesis +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart] +synonym: "apoptosis involved in heart morphogenesis" NARROW [] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2009-10-20T09:40:22Z + +[Term] +id: GO:0003279 +name: cardiac septum development +namespace: biological_process +def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] +synonym: "heart septum development" EXACT [GOC:mtg_heart] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0003205 ! cardiac chamber development +created_by: dph +creation_date: 2009-10-20T09:45:13Z + +[Term] +id: GO:0003281 +name: ventricular septum development +namespace: biological_process +def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart] +synonym: "interventricular septum development" EXACT [GOC:mtg_heart] +synonym: "septum inferius development" NARROW [GOC:mtg_heart] +is_a: GO:0003279 ! cardiac septum development +relationship: part_of GO:0003231 ! cardiac ventricle development +created_by: dph +creation_date: 2009-10-20T10:04:51Z + +[Term] +id: GO:0003282 +name: ventricular septum intermedium development +namespace: biological_process +def: "The progression of the ventricular septum intermedium over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003281 ! ventricular septum development +created_by: dph +creation_date: 2009-10-20T10:09:53Z + +[Term] +id: GO:0003283 +name: atrial septum development +namespace: biological_process +def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003279 ! cardiac septum development +relationship: part_of GO:0003230 ! cardiac atrium development +created_by: dph +creation_date: 2009-10-20T10:10:38Z + +[Term] +id: GO:0003284 +name: septum primum development +namespace: biological_process +def: "The progression of the septum primum over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003283 ! atrial septum development +created_by: dph +creation_date: 2009-10-20T10:12:26Z + +[Term] +id: GO:0003285 +name: septum secundum development +namespace: biological_process +def: "The progression of the septum secundum over time, from its initial formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003283 ! atrial septum development +created_by: dph +creation_date: 2009-10-20T10:21:13Z + +[Term] +id: GO:0003286 +name: atrial septum intermedium development +namespace: biological_process +def: "The progression of the atrial septum intermedium over time, from its formation to the mature structure." [GOC:mtg_heart] +is_a: GO:0003283 ! atrial septum development +created_by: dph +creation_date: 2009-10-20T10:23:52Z + +[Term] +id: GO:0003288 +name: ventricular septum intermedium morphogenesis +namespace: biological_process +def: "The developmental process in which a ventricular septum intermedium is generated and organized." [GOC:mtg_heart] +is_a: GO:0060412 ! ventricular septum morphogenesis +created_by: dph +creation_date: 2009-10-20T10:58:48Z + +[Term] +id: GO:0003289 +name: atrial septum primum morphogenesis +namespace: biological_process +def: "The process in which anatomical structure of an atrial septum primum is generated and organized." [GOC:mtg_heart] +is_a: GO:0060413 ! atrial septum morphogenesis +relationship: part_of GO:0003284 ! septum primum development +created_by: dph +creation_date: 2009-10-20T10:32:32Z + +[Term] +id: GO:0003290 +name: atrial septum secundum morphogenesis +namespace: biological_process +def: "The process in which anatomical structure of an atrial septum secundum is generated and organized." [GOC:mtg_heart] +is_a: GO:0060413 ! atrial septum morphogenesis +relationship: part_of GO:0003285 ! septum secundum development +created_by: dph +creation_date: 2009-10-20T10:33:57Z + +[Term] +id: GO:0003291 +name: atrial septum intermedium morphogenesis +namespace: biological_process +def: "The process in which anatomical structure of an atrial septum intermedium is generated and organized." [GOC:mtg_heart] +is_a: GO:0060413 ! atrial septum morphogenesis +relationship: part_of GO:0003286 ! atrial septum intermedium development +created_by: dph +creation_date: 2009-10-20T10:35:04Z + +[Term] +id: GO:0003292 +name: cardiac septum cell differentiation +namespace: biological_process +def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart] +is_a: GO:0035051 ! cardiocyte differentiation +relationship: part_of GO:0003279 ! cardiac septum development +created_by: dph +creation_date: 2009-10-20T11:03:46Z + +[Term] +id: GO:0003293 +name: heart valve cell differentiation +namespace: biological_process +def: "The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve." [GOC:mtg_heart] +is_a: GO:0035051 ! cardiocyte differentiation +relationship: part_of GO:0003170 ! heart valve development +created_by: dph +creation_date: 2009-10-20T11:06:46Z + +[Term] +id: GO:0003294 +name: atrial ventricular junction remodeling +namespace: biological_process +def: "The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle." [GOC:mtg_heart] +synonym: "atrio-ventricular junction remodeling" RELATED [GOC:mtg_heart] +synonym: "atrioventricular junction remodeling" EXACT [GOC:mtg_heart] +is_a: GO:0048771 ! tissue remodeling +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2009-10-22T08:35:36Z + +[Term] +id: GO:0003295 +name: cell proliferation involved in atrial ventricular junction remodeling +namespace: biological_process +def: "The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_heart] +synonym: "cell proliferation involved in atrio-ventricular junction remodeling" EXACT [GOC:mtg_heart] +synonym: "cell proliferation involved in atrioventricular junction remodeling" EXACT [GOC:mtg_heart] +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003294 ! atrial ventricular junction remodeling +relationship: part_of GO:0003294 ! atrial ventricular junction remodeling +created_by: dph +creation_date: 2009-10-22T08:38:30Z + +[Term] +id: GO:0003296 +name: apoptotic process involved in atrial ventricular junction remodeling +namespace: biological_process +def: "Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction." [GOC:mtg_apoptosis, GOC:mtg_heart] +synonym: "apoptosis involved in atrial ventricular junction remodeling" NARROW [] +synonym: "apoptosis involved in atrio-ventricular junction remodeling" EXACT [GOC:mtg_heart] +synonym: "apoptosis involved in atrioventricular junction remodeling" EXACT [GOC:mtg_heart] +is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0003294 ! atrial ventricular junction remodeling +relationship: part_of GO:0003294 ! atrial ventricular junction remodeling +created_by: dph +creation_date: 2009-10-22T08:43:11Z + +[Term] +id: GO:0003297 +name: heart wedging +namespace: biological_process +def: "The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart." [GOC:mtg_heart] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2009-10-22T08:52:58Z + +[Term] +id: GO:0003298 +name: physiological muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart] +is_a: GO:0014896 ! muscle hypertrophy +created_by: dph +creation_date: 2009-10-22T09:24:51Z + +[Term] +id: GO:0003299 +name: muscle hypertrophy in response to stress +namespace: biological_process +def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis." [GOC:mtg_heart] +is_a: GO:0006950 ! response to stress +is_a: GO:0014896 ! muscle hypertrophy +is_a: GO:0043500 ! muscle adaptation +created_by: dph +creation_date: 2009-10-22T09:26:10Z + +[Term] +id: GO:0003300 +name: cardiac muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart] +is_a: GO:0014897 ! striated muscle hypertrophy +created_by: dph +creation_date: 2009-10-22T10:33:56Z + +[Term] +id: GO:0003301 +name: physiological cardiac muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +is_a: GO:0003298 ! physiological muscle hypertrophy +is_a: GO:0003300 ! cardiac muscle hypertrophy +relationship: part_of GO:0055017 ! cardiac muscle tissue growth +created_by: dph +creation_date: 2009-10-22T10:38:10Z + +[Term] +id: GO:0003302 +name: transforming growth factor beta receptor signaling pathway involved in heart jogging +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging." [GOC:mtg_heart, GOC:signaling] +synonym: "transforming growth factor beta receptor signalling pathway involved in heart jogging" EXACT [GOC:mah] +is_a: GO:0035463 ! transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry +is_a: GO:1905313 ! transforming growth factor beta receptor signaling pathway involved in heart development +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0003146 ! heart jogging +relationship: part_of GO:0003146 ! heart jogging +created_by: dph +creation_date: 2009-10-22T10:51:58Z + +[Term] +id: GO:0003303 +name: BMP signaling pathway involved in heart jogging +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging." [GOC:mtg_heart] +synonym: "BMP signalling pathway involved in heart jogging" EXACT [GOC:mah] +is_a: GO:0003154 ! BMP signaling pathway involved in determination of left/right symmetry +is_a: GO:0061312 ! BMP signaling pathway involved in heart development +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0003146 ! heart jogging +relationship: part_of GO:0003146 ! heart jogging +created_by: dph +creation_date: 2009-10-22T11:00:58Z + +[Term] +id: GO:0003304 +name: myocardial epithelial involution involved in heart jogging +namespace: biological_process +def: "The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging." [GOC:mtg_heart] +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0003146 ! heart jogging +created_by: dph +creation_date: 2009-10-22T11:03:33Z + +[Term] +id: GO:0003305 +name: cell migration involved in heart jogging +namespace: biological_process +def: "The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging." [GOC:mtg_heart] +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0003146 ! heart jogging +relationship: part_of GO:0003146 ! heart jogging +created_by: dph +creation_date: 2009-10-22T11:05:46Z + +[Term] +id: GO:0003306 +name: Wnt signaling pathway involved in heart development +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time." [GOC:mtg_heart] +synonym: "Wnt receptor signaling pathway involved in heart development" EXACT [] +synonym: "Wnt receptor signalling pathway involved in heart development" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in heart development" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-22T12:26:07Z + +[Term] +id: GO:0003307 +name: regulation of Wnt signaling pathway involved in heart development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time." [GOC:mtg_heart] +synonym: "regulation of Wnt receptor signaling pathway involved in heart development" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway involved in heart development" EXACT [GOC:mah] +synonym: "regulation of Wnt-activated signaling pathway involved in heart development" EXACT [GOC:signaling] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003306 ! Wnt signaling pathway involved in heart development +relationship: regulates GO:0003306 ! Wnt signaling pathway involved in heart development +created_by: dph +creation_date: 2009-10-22T12:32:10Z + +[Term] +id: GO:0003308 +name: negative regulation of Wnt signaling pathway involved in heart development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time." [GOC:mtg_heart] +synonym: "negative regulation of Wnt receptor signaling pathway involved in heart development" EXACT [] +synonym: "negative regulation of Wnt receptor signalling pathway involved in heart development" EXACT [GOC:mah] +synonym: "negative regulation of Wnt-activated signaling pathway involved in heart development" EXACT [GOC:signaling] +is_a: GO:0003307 ! regulation of Wnt signaling pathway involved in heart development +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003306 ! Wnt signaling pathway involved in heart development +relationship: negatively_regulates GO:0003306 ! Wnt signaling pathway involved in heart development +created_by: dph +creation_date: 2009-10-22T12:36:11Z + +[Term] +id: GO:0003309 +name: type B pancreatic cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772] +synonym: "pancreatic B cell differentiation" EXACT [GOC:mah] +synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph] +is_a: GO:0035883 ! enteroendocrine cell differentiation +relationship: part_of GO:0031018 ! endocrine pancreas development +created_by: dph +creation_date: 2009-10-26T09:27:23Z + +[Term] +id: GO:0003310 +name: pancreatic A cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772] +synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph] +is_a: GO:0035883 ! enteroendocrine cell differentiation +relationship: part_of GO:0031018 ! endocrine pancreas development +created_by: dph +creation_date: 2009-10-26T09:28:05Z + +[Term] +id: GO:0003311 +name: pancreatic D cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772] +synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph] +is_a: GO:0035883 ! enteroendocrine cell differentiation +relationship: part_of GO:0031018 ! endocrine pancreas development +created_by: dph +creation_date: 2009-10-26T09:30:27Z + +[Term] +id: GO:0003312 +name: pancreatic PP cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772] +synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph] +is_a: GO:0035883 ! enteroendocrine cell differentiation +relationship: part_of GO:0031018 ! endocrine pancreas development +created_by: dph +creation_date: 2009-10-26T09:32:32Z + +[Term] +id: GO:0003313 +name: heart rudiment development +namespace: biological_process +def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart] +synonym: "heart cone development" EXACT [GOC:mtg_heart] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0035050 ! embryonic heart tube development +created_by: dph +creation_date: 2009-10-27T08:32:40Z + +[Term] +id: GO:0003314 +name: heart rudiment morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart] +synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0003313 ! heart rudiment development +created_by: dph +creation_date: 2009-10-27T08:38:04Z + +[Term] +id: GO:0003315 +name: heart rudiment formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart] +synonym: "heart cone formation" EXACT [GOC:mtg_heart] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003314 ! heart rudiment morphogenesis +created_by: dph +creation_date: 2009-10-27T08:43:37Z + +[Term] +id: GO:0003316 +name: establishment of myocardial progenitor cell apical/basal polarity +namespace: biological_process +def: "The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment." [GOC:mtg_heart] +synonym: "myocardial progenitor epithelial polarization" EXACT [GOC:mtg_heart] +is_a: GO:0045198 ! establishment of epithelial cell apical/basal polarity +relationship: part_of GO:0003315 ! heart rudiment formation +created_by: dph +creation_date: 2009-10-27T09:01:26Z + +[Term] +id: GO:0003317 +name: cardioblast cell midline fusion +namespace: biological_process +def: "The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment." [GOC:mtg_heart] +synonym: "cardiac progenitor cell midline fusion" EXACT [GOC:mtg_heart] +is_a: GO:0034109 ! homotypic cell-cell adhesion +relationship: part_of GO:0003315 ! heart rudiment formation +created_by: dph +creation_date: 2009-10-27T09:08:57Z + +[Term] +id: GO:0003318 +name: cell migration to the midline involved in heart development +namespace: biological_process +def: "The orderly movement of a cell toward the midline that contributes to the progression of the heart over time." [GOC:mtg_heart] +is_a: GO:0060973 ! cell migration involved in heart development +created_by: dph +creation_date: 2009-10-27T09:15:43Z + +[Term] +id: GO:0003319 +name: cardioblast migration to the midline involved in heart rudiment formation +namespace: biological_process +def: "The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment." [GOC:mtg_heart] +is_a: GO:0003318 ! cell migration to the midline involved in heart development +relationship: part_of GO:0003315 ! heart rudiment formation +created_by: dph +creation_date: 2009-10-27T09:21:36Z + +[Term] +id: GO:0003320 +name: heart rudiment involution +namespace: biological_process +def: "The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube." [GOC:mtg_heart] +is_a: GO:0003152 ! morphogenesis of an epithelial fold involved in embryonic heart tube formation +created_by: dph +creation_date: 2009-10-27T09:29:24Z + +[Term] +id: GO:0003321 +name: positive regulation of blood pressure by epinephrine-norepinephrine +namespace: biological_process +def: "Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine." [GOC:dph] +is_a: GO:0001993 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine +is_a: GO:0045777 ! positive regulation of blood pressure +created_by: dph +creation_date: 2009-10-29T01:52:50Z + +[Term] +id: GO:0003322 +name: pancreatic A cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] +synonym: "pancreatic alpha cell development" EXACT [GOC:dph] +is_a: GO:0002068 ! glandular epithelial cell development +relationship: part_of GO:0003310 ! pancreatic A cell differentiation +created_by: dph +creation_date: 2009-11-02T08:13:55Z + +[Term] +id: GO:0003323 +name: type B pancreatic cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] +synonym: "pancreatic B cell development" EXACT [GOC:mah] +synonym: "pancreatic beta cell development" EXACT [GOC:dph] +is_a: GO:0002068 ! glandular epithelial cell development +relationship: part_of GO:0003309 ! type B pancreatic cell differentiation +created_by: dph +creation_date: 2009-11-02T08:20:11Z + +[Term] +id: GO:0003324 +name: pancreatic D cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] +synonym: "pancreatic delta cell development" EXACT [GOC:dph] +is_a: GO:0002068 ! glandular epithelial cell development +relationship: part_of GO:0003311 ! pancreatic D cell differentiation +created_by: dph +creation_date: 2009-11-02T08:23:26Z + +[Term] +id: GO:0003325 +name: pancreatic PP cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] +is_a: GO:0002068 ! glandular epithelial cell development +relationship: part_of GO:0003312 ! pancreatic PP cell differentiation +created_by: dph +creation_date: 2009-11-02T08:25:03Z + +[Term] +id: GO:0003326 +name: pancreatic A cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0003310 ! pancreatic A cell differentiation +created_by: dph +creation_date: 2009-11-02T08:29:00Z + +[Term] +id: GO:0003327 +name: type B pancreatic cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] +synonym: "pancreatic B cell fate commitment" EXACT [GOC:mah] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0003309 ! type B pancreatic cell differentiation +created_by: dph +creation_date: 2009-11-02T08:31:24Z + +[Term] +id: GO:0003328 +name: pancreatic D cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0003311 ! pancreatic D cell differentiation +created_by: dph +creation_date: 2009-11-02T08:33:36Z + +[Term] +id: GO:0003329 +name: pancreatic PP cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0003312 ! pancreatic PP cell differentiation +created_by: dph +creation_date: 2009-11-02T08:35:13Z + +[Term] +id: GO:0003330 +name: regulation of extracellular matrix constituent secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] +is_a: GO:1903053 ! regulation of extracellular matrix organization +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070278 ! extracellular matrix constituent secretion +relationship: regulates GO:0070278 ! extracellular matrix constituent secretion +created_by: dph +creation_date: 2009-11-02T02:07:40Z + +[Term] +id: GO:0003331 +name: positive regulation of extracellular matrix constituent secretion +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] +is_a: GO:0003330 ! regulation of extracellular matrix constituent secretion +is_a: GO:1903055 ! positive regulation of extracellular matrix organization +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070278 ! extracellular matrix constituent secretion +relationship: positively_regulates GO:0070278 ! extracellular matrix constituent secretion +created_by: dph +creation_date: 2009-11-02T02:11:22Z + +[Term] +id: GO:0003332 +name: negative regulation of extracellular matrix constituent secretion +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells." [GOC:dph, GOC:tb] +is_a: GO:0003330 ! regulation of extracellular matrix constituent secretion +is_a: GO:1903054 ! negative regulation of extracellular matrix organization +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070278 ! extracellular matrix constituent secretion +relationship: negatively_regulates GO:0070278 ! extracellular matrix constituent secretion +created_by: dph +creation_date: 2009-11-02T02:13:49Z + +[Term] +id: GO:0003333 +name: amino acid transmembrane transport +namespace: biological_process +def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "amino acid membrane transport" EXACT [] +is_a: GO:0006865 ! amino acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: dph +creation_date: 2009-11-02T02:36:11Z + +[Term] +id: GO:0003334 +name: keratinocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0030216 ! keratinocyte differentiation +created_by: dph +creation_date: 2009-11-24T08:55:57Z + +[Term] +id: GO:0003335 +name: corneocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0003334 ! keratinocyte development +created_by: dph +creation_date: 2009-11-24T09:01:02Z + +[Term] +id: GO:0003336 +name: corneocyte desquamation +namespace: biological_process +def: "The delamination process that results in the shedding of a corneocyte from the surface of the epidermis." [GOC:dph] +synonym: "epidermal desquamation" EXACT [GOC:dph] +is_a: GO:0060232 ! delamination +relationship: part_of GO:0003335 ! corneocyte development +created_by: dph +creation_date: 2009-11-24T09:11:53Z + +[Term] +id: GO:0003337 +name: mesenchymal to epithelial transition involved in metanephros morphogenesis +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] +synonym: "metanephric mesenchyme to epithelial transition" RELATED [GOC:dph] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +is_a: GO:0060231 ! mesenchymal to epithelial transition +is_a: GO:0072202 ! cell differentiation involved in metanephros development +intersection_of: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: part_of GO:0003338 ! metanephros morphogenesis +relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis +created_by: dph +creation_date: 2009-11-24T09:29:49Z + +[Term] +id: GO:0003338 +name: metanephros morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf] +is_a: GO:0060993 ! kidney morphogenesis +relationship: part_of GO:0001656 ! metanephros development +created_by: dph +creation_date: 2009-11-24T09:32:09Z + +[Term] +id: GO:0003339 +name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +relationship: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +created_by: dph +creation_date: 2009-11-24T09:43:04Z + +[Term] +id: GO:0003340 +name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] +is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +relationship: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +created_by: dph +creation_date: 2009-11-24T09:46:12Z + +[Term] +id: GO:0003341 +name: cilium movement +namespace: biological_process +alt_id: GO:0036142 +def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "ciliary motility" RELATED [] +synonym: "cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "flagellar motility" RELATED [] +synonym: "flagellar movement" NARROW [GOC:bf] +synonym: "flagellum movement" NARROW [] +synonym: "microtubule-based flagellum movement" EXACT [] +is_a: GO:0007018 ! microtubule-based movement +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +property_value: RO:0002161 NCBITaxon:4890 +property_value: RO:0002161 NCBITaxon:5782 +created_by: dph +creation_date: 2009-11-24T09:56:26Z + +[Term] +id: GO:0003342 +name: proepicardium development +namespace: biological_process +def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343] +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0003343 ! septum transversum development +created_by: dph +creation_date: 2009-12-01T10:30:17Z + +[Term] +id: GO:0003343 +name: septum transversum development +namespace: biological_process +def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343] +is_a: GO:0060485 ! mesenchyme development +created_by: dph +creation_date: 2009-12-01T10:40:17Z + +[Term] +id: GO:0003344 +name: pericardium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343] +is_a: GO:0002011 ! morphogenesis of an epithelial sheet +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0060039 ! pericardium development +created_by: dph +creation_date: 2009-12-01T10:46:34Z + +[Term] +id: GO:0003345 +name: proepicardium cell migration involved in pericardium morphogenesis +namespace: biological_process +def: "The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart." [GOC:dph, PMID:18722343] +is_a: GO:0060973 ! cell migration involved in heart development +relationship: part_of GO:0003344 ! pericardium morphogenesis +created_by: dph +creation_date: 2009-12-01T10:49:32Z + +[Term] +id: GO:0003346 +name: epicardium-derived cell migration to the myocardium +namespace: biological_process +def: "The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium." [GOC:dph, PMID:18722343] +is_a: GO:0060973 ! cell migration involved in heart development +created_by: dph +creation_date: 2009-12-01T11:00:42Z + +[Term] +id: GO:0003347 +name: epicardial cell to mesenchymal cell transition +namespace: biological_process +def: "A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium." [GOC:dph, PMID:18722343] +is_a: GO:0001837 ! epithelial to mesenchymal transition +created_by: dph +creation_date: 2009-12-01T11:05:39Z + +[Term] +id: GO:0003348 +name: cardiac endothelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] +is_a: GO:0035051 ! cardiocyte differentiation +is_a: GO:0045446 ! endothelial cell differentiation +created_by: dph +creation_date: 2009-12-01T11:12:05Z + +[Term] +id: GO:0003349 +name: epicardium-derived cardiac endothelial cell differentiation +namespace: biological_process +def: "The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] +is_a: GO:0003348 ! cardiac endothelial cell differentiation +created_by: dph +creation_date: 2009-12-01T11:17:49Z + +[Term] +id: GO:0003350 +name: pulmonary myocardium development +namespace: biological_process +def: "The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein." [GOC:dph, PMID:17638577] +is_a: GO:0014706 ! striated muscle tissue development +relationship: part_of GO:0060841 ! venous blood vessel development +created_by: dph +creation_date: 2009-12-01T12:50:06Z + +[Term] +id: GO:0003351 +name: epithelial cilium movement involved in extracellular fluid movement +namespace: biological_process +def: "The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid." [GOC:dph, GOC:krc] +synonym: "cilium movement involved in fluid flow" RELATED [GOC:cilia] +synonym: "epithelial cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003341 ! cilium movement +is_a: GO:0006858 ! extracellular transport +is_a: GO:0099111 ! microtubule-based transport +created_by: dph +creation_date: 2009-12-03T10:08:25Z + +[Term] +id: GO:0003352 +name: regulation of cilium movement +namespace: biological_process +alt_id: GO:1900172 +def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "regulation of flagellar movement" RELATED [GOC:TermGenie] +synonym: "regulation of flagellum movement" RELATED [] +synonym: "regulation of microtubule-based flagellum movement" EXACT [] +is_a: GO:0060632 ! regulation of microtubule-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003341 ! cilium movement +relationship: regulates GO:0003341 ! cilium movement +created_by: dph +creation_date: 2009-12-03T10:12:00Z + +[Term] +id: GO:0003353 +name: positive regulation of cilium movement +namespace: biological_process +alt_id: GO:1900174 +def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "positive regulation of flagellar movement" RELATED [GOC:TermGenie] +synonym: "positive regulation of flagellum movement" RELATED [] +synonym: "positive regulation of microtubule-based flagellum movement" EXACT [] +is_a: GO:0003352 ! regulation of cilium movement +is_a: GO:0051272 ! positive regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003341 ! cilium movement +relationship: positively_regulates GO:0003341 ! cilium movement +created_by: dph +creation_date: 2009-12-03T10:16:10Z + +[Term] +id: GO:0003354 +name: negative regulation of cilium movement +namespace: biological_process +alt_id: GO:1900173 +def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "negative regulation of flagellum movement" RELATED [] +synonym: "negative regulation of microtubule-based flagellum movement" EXACT [] +is_a: GO:0003352 ! regulation of cilium movement +is_a: GO:0051271 ! negative regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003341 ! cilium movement +relationship: negatively_regulates GO:0003341 ! cilium movement +created_by: dph +creation_date: 2009-12-03T10:17:47Z + +[Term] +id: GO:0003355 +name: cilium movement involved in otolith formation +namespace: biological_process +def: "The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles." [GOC:dph, GOC:krc, PMID:19043402] +is_a: GO:0003351 ! epithelial cilium movement involved in extracellular fluid movement +intersection_of: GO:0003341 ! cilium movement +intersection_of: part_of GO:0032475 ! otolith formation +relationship: part_of GO:0032475 ! otolith formation +created_by: dph +creation_date: 2009-12-03T10:21:08Z + +[Term] +id: GO:0003356 +name: regulation of cilium beat frequency +namespace: biological_process +alt_id: GO:0036144 +def: "Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "regulation of flagellum beat frequency" RELATED [] +synonym: "regulation of microtubule-based flagellum beat frequency" EXACT [] +is_a: GO:0003352 ! regulation of cilium movement +created_by: dph +creation_date: 2009-12-03T10:27:12Z + +[Term] +id: GO:0003357 +name: noradrenergic neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph] +synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph] +is_a: GO:0030182 ! neuron differentiation +created_by: dph +creation_date: 2009-12-03T10:34:30Z + +[Term] +id: GO:0003358 +name: noradrenergic neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] +synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0003357 ! noradrenergic neuron differentiation +created_by: dph +creation_date: 2009-12-03T10:38:37Z + +[Term] +id: GO:0003359 +name: noradrenergic neuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron." [GOC:dph] +synonym: "norepinephrine secreting neuron fate commitment" EXACT [GOC:dph] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0003357 ! noradrenergic neuron differentiation +created_by: dph +creation_date: 2009-12-03T10:41:08Z + +[Term] +id: GO:0003360 +name: brainstem development +namespace: biological_process +def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +created_by: dph +creation_date: 2009-12-03T10:47:20Z + +[Term] +id: GO:0003361 +name: noradrenergic neuron differentiation involved in brainstem development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph] +is_a: GO:0003357 ! noradrenergic neuron differentiation +intersection_of: GO:0003357 ! noradrenergic neuron differentiation +intersection_of: part_of GO:0003360 ! brainstem development +relationship: part_of GO:0003360 ! brainstem development +created_by: dph +creation_date: 2009-12-03T10:53:30Z + +[Term] +id: GO:0003362 +name: noradrenergic neuron fate commitment involved in brainstem development +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem." [GOC:dph] +is_a: GO:0003359 ! noradrenergic neuron fate commitment +intersection_of: GO:0003359 ! noradrenergic neuron fate commitment +intersection_of: part_of GO:0003360 ! brainstem development +relationship: part_of GO:0003361 ! noradrenergic neuron differentiation involved in brainstem development +created_by: dph +creation_date: 2009-12-03T10:56:16Z + +[Term] +id: GO:0003363 +name: lamellipodium assembly involved in ameboidal cell migration +namespace: biological_process +def: "Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030032 ! lamellipodium assembly +intersection_of: GO:0030032 ! lamellipodium assembly +intersection_of: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0001667 ! ameboidal-type cell migration +created_by: dph +creation_date: 2009-12-08T04:38:04Z + +[Term] +id: GO:0003364 +name: lamellipodium assembly involved in mesendodermal cell migration +namespace: biological_process +def: "Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003363 ! lamellipodium assembly involved in ameboidal cell migration +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +intersection_of: GO:0030032 ! lamellipodium assembly +intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration +relationship: part_of GO:0090134 ! cell migration involved in mesendoderm migration +created_by: dph +creation_date: 2009-12-08T04:46:39Z + +[Term] +id: GO:0003365 +name: establishment of cell polarity involved in ameboidal cell migration +namespace: biological_process +def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030010 ! establishment of cell polarity +intersection_of: GO:0030010 ! establishment of cell polarity +intersection_of: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0001667 ! ameboidal-type cell migration +created_by: dph +creation_date: 2009-12-08T04:50:41Z + +[Term] +id: GO:0003366 +name: cell-matrix adhesion involved in ameboidal cell migration +namespace: biological_process +def: "The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007160 ! cell-matrix adhesion +intersection_of: GO:0007160 ! cell-matrix adhesion +intersection_of: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0001667 ! ameboidal-type cell migration +created_by: dph +creation_date: 2009-12-08T04:54:33Z + +[Term] +id: GO:0003367 +name: cell-cell adhesion involved in ameboidal cell migration +namespace: biological_process +def: "The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration +relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration +created_by: dph +creation_date: 2009-12-08T05:15:49Z + +[Term] +id: GO:0003368 +name: cell-matrix adhesion involved in mesendodermal cell migration +namespace: biological_process +def: "The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003366 ! cell-matrix adhesion involved in ameboidal cell migration +intersection_of: GO:0007160 ! cell-matrix adhesion +intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration +relationship: part_of GO:0090134 ! cell migration involved in mesendoderm migration +created_by: dph +creation_date: 2009-12-08T05:26:12Z + +[Term] +id: GO:0003369 +name: establishment of cell polarity involved in mesendodermal cell migration +namespace: biological_process +def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration +intersection_of: GO:0030010 ! establishment of cell polarity +intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration +relationship: part_of GO:0090134 ! cell migration involved in mesendoderm migration +created_by: dph +creation_date: 2009-12-08T05:31:51Z + +[Term] +id: GO:0003370 +name: cell-cell adhesion involved in mesendodermal cell migration +namespace: biological_process +def: "The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003367 ! cell-cell adhesion involved in ameboidal cell migration +is_a: GO:0070586 ! cell-cell adhesion involved in gastrulation +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0003369 ! establishment of cell polarity involved in mesendodermal cell migration +relationship: part_of GO:0003369 ! establishment of cell polarity involved in mesendodermal cell migration +created_by: dph +creation_date: 2009-12-08T05:33:51Z + +[Term] +id: GO:0003371 +name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration +created_by: dph +creation_date: 2009-12-08T05:42:46Z + +[Term] +id: GO:0003372 +name: establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003380 ! establishment or maintenance of cytoskeleton polarity involved in gastrulation +intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: part_of GO:0090134 ! cell migration involved in mesendoderm migration +relationship: part_of GO:0003369 ! establishment of cell polarity involved in mesendodermal cell migration +created_by: dph +creation_date: 2009-12-08T05:46:23Z + +[Term] +id: GO:0003373 +name: dynamin family protein polymerization involved in membrane fission +namespace: biological_process +def: "The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0051258 ! protein polymerization +relationship: part_of GO:0090148 ! membrane fission +created_by: dph +creation_date: 2009-12-09T04:55:16Z + +[Term] +id: GO:0003374 +name: dynamin family protein polymerization involved in mitochondrial fission +namespace: biological_process +def: "The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003373 ! dynamin family protein polymerization involved in membrane fission +created_by: dph +creation_date: 2009-12-09T05:39:52Z + +[Term] +id: GO:0003375 +name: regulation of dynamin family protein polymerization involved in membrane fission +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0032271 ! regulation of protein polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003373 ! dynamin family protein polymerization involved in membrane fission +relationship: regulates GO:0003373 ! dynamin family protein polymerization involved in membrane fission +created_by: dph +creation_date: 2009-12-09T05:50:15Z + +[Term] +id: GO:0003376 +name: sphingosine-1-phosphate receptor signaling pathway +namespace: biological_process +alt_id: GO:0001789 +def: "A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:ascb_2009, GOC:signaling, PMID:14592418, PMID:22001186, Reactome:R-HSA-419428] +synonym: "S1P receptor signaling pathway" EXACT [GOC:bf] +synonym: "S1P signaling pathway" RELATED [GOC:bf] +synonym: "S1P-activated G-protein coupled receptor signaling pathway" EXACT [GOC:bf] +synonym: "S1P-activated GPCR signaling pathway" EXACT [GOC:bf] +synonym: "S1P-stimulated signal transduction pathway" EXACT [PMID:22001186] +synonym: "sphingolipid signaling pathway" BROAD [GOC:bf] +synonym: "sphingolipid signalling pathway" BROAD [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0090520 ! sphingolipid mediated signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15822 xsd:anyURI +created_by: dph +creation_date: 2009-12-09T06:30:12Z + +[Term] +id: GO:0003377 +name: obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway +namespace: biological_process +def: "OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis." [GOC:ascb_2009, GOC:dph, GOC:signaling, GOC:tb] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "regulation of apoptosis by sphingolipid signaling pathway" BROAD [GOC:bf] +synonym: "regulation of apoptosis by sphingolipid signalling pathway" BROAD [GOC:mah] +is_obsolete: true +created_by: dph +creation_date: 2009-12-09T06:32:22Z + +[Term] +id: GO:0003378 +name: obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway +namespace: biological_process +def: "OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "regulation of inflammatory response by sphingolipid signaling pathway" BROAD [GOC:bf] +synonym: "regulation of inflammatory response by sphingolipid signalling pathway" BROAD [GOC:mah] +is_obsolete: true +created_by: dph +creation_date: 2009-12-09T06:38:06Z + +[Term] +id: GO:0003379 +name: establishment of cell polarity involved in gastrulation cell migration +namespace: biological_process +def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration +intersection_of: GO:0030010 ! establishment of cell polarity +intersection_of: part_of GO:0042074 ! cell migration involved in gastrulation +relationship: part_of GO:0042074 ! cell migration involved in gastrulation +created_by: dph +creation_date: 2009-12-09T06:54:44Z + +[Term] +id: GO:0003380 +name: establishment or maintenance of cytoskeleton polarity involved in gastrulation +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration +intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration +created_by: dph +creation_date: 2009-12-09T07:10:57Z + +[Term] +id: GO:0003381 +name: epithelial cell morphogenesis involved in gastrulation +namespace: biological_process +def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003382 ! epithelial cell morphogenesis +intersection_of: GO:0003382 ! epithelial cell morphogenesis +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0007369 ! gastrulation +created_by: dph +creation_date: 2009-12-09T07:18:53Z + +[Term] +id: GO:0003382 +name: epithelial cell morphogenesis +namespace: biological_process +def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0002064 ! epithelial cell development +created_by: dph +creation_date: 2009-12-09T07:21:06Z + +[Term] +id: GO:0003383 +name: apical constriction +namespace: biological_process +def: "The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0070252 ! actin-mediated cell contraction +relationship: part_of GO:0003382 ! epithelial cell morphogenesis +created_by: dph +creation_date: 2009-12-09T07:30:34Z + +[Term] +id: GO:0003384 +name: apical constriction involved in gastrulation +namespace: biological_process +def: "The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003383 ! apical constriction +intersection_of: GO:0003383 ! apical constriction +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0003381 ! epithelial cell morphogenesis involved in gastrulation +created_by: dph +creation_date: 2009-12-09T07:35:38Z + +[Term] +id: GO:0003385 +name: cell-cell signaling involved in amphid sensory organ development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "cell-cell signalling involved in amphid sensory organ development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0003386 ! amphid sensory organ development +relationship: part_of GO:0003386 ! amphid sensory organ development +created_by: dph +creation_date: 2009-12-09T08:55:37Z + +[Term] +id: GO:0003386 +name: amphid sensory organ development +namespace: biological_process +def: "The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007423 ! sensory organ development +created_by: dph +creation_date: 2009-12-09T09:09:20Z + +[Term] +id: GO:0003387 +name: neuron differentiation involved in amphid sensory organ development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030182 ! neuron differentiation +intersection_of: GO:0030182 ! neuron differentiation +intersection_of: part_of GO:0003386 ! amphid sensory organ development +relationship: part_of GO:0003386 ! amphid sensory organ development +created_by: dph +creation_date: 2009-12-09T09:15:00Z + +[Term] +id: GO:0003388 +name: neuron development involved in amphid sensory organ development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048666 ! neuron development +intersection_of: GO:0048666 ! neuron development +intersection_of: part_of GO:0003386 ! amphid sensory organ development +relationship: part_of GO:0003387 ! neuron differentiation involved in amphid sensory organ development +created_by: dph +creation_date: 2009-12-09T09:18:06Z + +[Term] +id: GO:0003389 +name: retrograde extension +namespace: biological_process +def: "The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0031175 ! neuron projection development +created_by: dph +creation_date: 2009-12-09T09:22:03Z + +[Term] +id: GO:0003390 +name: dendrite development by retrograde extension +namespace: biological_process +def: "The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "dendrite retrograde extension" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003389 ! retrograde extension +is_a: GO:0016358 ! dendrite development +created_by: dph +creation_date: 2009-12-09T09:25:24Z + +[Term] +id: GO:0003391 +name: amphid sensory organ dendrite retrograde extension +namespace: biological_process +def: "The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003390 ! dendrite development by retrograde extension +relationship: part_of GO:0003388 ! neuron development involved in amphid sensory organ development +created_by: dph +creation_date: 2009-12-09T09:28:27Z + +[Term] +id: GO:0003392 +name: cell adhesion involved in retrograde extension +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007155 ! cell adhesion +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0003389 ! retrograde extension +relationship: part_of GO:0003389 ! retrograde extension +created_by: dph +creation_date: 2009-12-09T09:32:06Z + +[Term] +id: GO:0003393 +name: neuron migration involved in retrograde extension +namespace: biological_process +def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0001764 ! neuron migration +intersection_of: GO:0001764 ! neuron migration +intersection_of: part_of GO:0003389 ! retrograde extension +relationship: part_of GO:0003389 ! retrograde extension +created_by: dph +creation_date: 2009-12-09T09:36:03Z + +[Term] +id: GO:0003394 +name: cell adhesion involved in dendrite retrograde extension +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003392 ! cell adhesion involved in retrograde extension +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0003390 ! dendrite development by retrograde extension +relationship: part_of GO:0003390 ! dendrite development by retrograde extension +created_by: dph +creation_date: 2009-12-09T09:42:09Z + +[Term] +id: GO:0003395 +name: neuron migration involved in dendrite retrograde extension +namespace: biological_process +def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003393 ! neuron migration involved in retrograde extension +intersection_of: GO:0001764 ! neuron migration +intersection_of: part_of GO:0003390 ! dendrite development by retrograde extension +relationship: part_of GO:0003390 ! dendrite development by retrograde extension +created_by: dph +creation_date: 2009-12-09T09:44:24Z + +[Term] +id: GO:0003396 +name: cell adhesion involved in amphid sensory organ dendrite retrograde extension +namespace: biological_process +def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003394 ! cell adhesion involved in dendrite retrograde extension +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension +relationship: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension +created_by: dph +creation_date: 2009-12-09T09:50:18Z + +[Term] +id: GO:0003397 +name: neuron migration involved in amphid sensory organ dendrite retrograde extension +namespace: biological_process +def: "The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003395 ! neuron migration involved in dendrite retrograde extension +intersection_of: GO:0001764 ! neuron migration +intersection_of: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension +relationship: part_of GO:0003391 ! amphid sensory organ dendrite retrograde extension +created_by: dph +creation_date: 2009-12-09T09:52:18Z + +[Term] +id: GO:0003398 +name: glial cell differentiation involved in amphid sensory organ development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010001 ! glial cell differentiation +intersection_of: GO:0010001 ! glial cell differentiation +intersection_of: part_of GO:0003386 ! amphid sensory organ development +relationship: part_of GO:0003386 ! amphid sensory organ development +created_by: dph +creation_date: 2009-12-09T09:55:27Z + +[Term] +id: GO:0003399 +name: cytoneme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis +created_by: dph +creation_date: 2009-12-09T10:03:32Z + +[Term] +id: GO:0003400 +name: regulation of COPII vesicle coating +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat." [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0048209 ! regulation of vesicle targeting, to, from or within Golgi +is_a: GO:0090113 ! regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048208 ! COPII vesicle coating +relationship: regulates GO:0048208 ! COPII vesicle coating +created_by: dph +creation_date: 2009-12-17T08:38:14Z + +[Term] +id: GO:0003401 +name: axis elongation +namespace: biological_process +def: "The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "elongation of an axis" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +created_by: dph +creation_date: 2009-12-21T01:12:15Z + +[Term] +id: GO:0003402 +name: planar cell polarity pathway involved in axis elongation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: part_of GO:0003401 ! axis elongation +relationship: part_of GO:0003401 ! axis elongation +created_by: dph +creation_date: 2009-12-21T01:22:11Z + +[Term] +id: GO:0003403 +name: optic vesicle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003404 ! optic vesicle morphogenesis +relationship: part_of GO:0060900 ! embryonic camera-type eye formation +created_by: dph +creation_date: 2009-12-21T01:42:37Z + +[Term] +id: GO:0003404 +name: optic vesicle morphogenesis +namespace: biological_process +def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis +created_by: dph +creation_date: 2009-12-21T01:54:34Z + +[Term] +id: GO:0003405 +name: optic vesicle elongation +namespace: biological_process +def: "The developmental growth that results in the lengthening of the optic vesicle in the posterior direction." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0003404 ! optic vesicle morphogenesis +created_by: dph +creation_date: 2009-12-21T01:59:50Z + +[Term] +id: GO:0003406 +name: retinal pigment epithelium development +namespace: biological_process +def: "The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "RPE development" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0060041 ! retina development in camera-type eye +created_by: dph +creation_date: 2009-12-21T02:04:27Z + +[Term] +id: GO:0003407 +name: neural retina development +namespace: biological_process +def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060041 ! retina development in camera-type eye +created_by: dph +creation_date: 2009-12-21T02:15:14Z + +[Term] +id: GO:0003408 +name: optic cup formation involved in camera-type eye development +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0002072 ! optic cup morphogenesis involved in camera-type eye development +created_by: dph +creation_date: 2009-12-21T02:37:12Z + +[Term] +id: GO:0003409 +name: optic cup structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "optic cup structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0002072 ! optic cup morphogenesis involved in camera-type eye development +created_by: dph +creation_date: 2009-12-21T02:44:20Z + +[Term] +id: GO:0003410 +name: anterior rotation of the optic cup +namespace: biological_process +def: "A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043010 ! camera-type eye development +created_by: dph +creation_date: 2009-12-21T02:49:48Z + +[Term] +id: GO:0003411 +name: cell motility involved in camera-type eye morphogenesis +namespace: biological_process +def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048870 ! cell motility +intersection_of: GO:0048870 ! cell motility +intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis +relationship: part_of GO:0048593 ! camera-type eye morphogenesis +created_by: dph +creation_date: 2009-12-21T03:04:27Z + +[Term] +id: GO:0003412 +name: establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis +namespace: biological_process +def: "The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0045198 ! establishment of epithelial cell apical/basal polarity +intersection_of: GO:0045198 ! establishment of epithelial cell apical/basal polarity +intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis +relationship: part_of GO:0048593 ! camera-type eye morphogenesis +created_by: dph +creation_date: 2009-12-21T03:09:23Z + +[Term] +id: GO:0003413 +name: chondrocyte differentiation involved in endochondral bone morphogenesis +namespace: biological_process +def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0002062 ! chondrocyte differentiation +intersection_of: GO:0002062 ! chondrocyte differentiation +intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis +relationship: part_of GO:0060351 ! cartilage development involved in endochondral bone morphogenesis +created_by: dph +creation_date: 2009-12-22T08:39:58Z + +[Term] +id: GO:0003414 +name: chondrocyte morphogenesis involved in endochondral bone morphogenesis +namespace: biological_process +def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090171 ! chondrocyte morphogenesis +intersection_of: GO:0090171 ! chondrocyte morphogenesis +intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis +relationship: part_of GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis +created_by: dph +creation_date: 2009-12-22T08:42:55Z + +[Term] +id: GO:0003415 +name: chondrocyte hypertrophy +namespace: biological_process +def: "The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0002063 ! chondrocyte development +created_by: dph +creation_date: 2009-12-22T08:48:44Z + +[Term] +id: GO:0003416 +name: endochondral bone growth +namespace: biological_process +def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0098868 ! bone growth +created_by: dph +creation_date: 2009-12-22T08:52:55Z + +[Term] +id: GO:0003417 +name: growth plate cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060351 ! cartilage development involved in endochondral bone morphogenesis +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0003416 ! endochondral bone growth +created_by: dph +creation_date: 2009-12-22T08:57:42Z + +[Term] +id: GO:0003418 +name: growth plate cartilage chondrocyte differentiation +namespace: biological_process +def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis +relationship: part_of GO:0003417 ! growth plate cartilage development +created_by: dph +creation_date: 2009-12-22T09:00:56Z + +[Term] +id: GO:0003419 +name: growth plate cartilage chondrocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0008283 ! cell population proliferation +relationship: part_of GO:0003417 ! growth plate cartilage development +created_by: dph +creation_date: 2009-12-22T09:02:51Z + +[Term] +id: GO:0003420 +name: regulation of growth plate cartilage chondrocyte proliferation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:0061035 ! regulation of cartilage development +is_a: GO:1903010 ! regulation of bone development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +relationship: regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +created_by: dph +creation_date: 2009-12-22T09:07:40Z + +[Term] +id: GO:0003421 +name: growth plate cartilage axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "growth plate cartilage axis determination" RELATED [GOC:dph] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis +created_by: dph +creation_date: 2009-12-22T09:16:33Z + +[Term] +id: GO:0003422 +name: growth plate cartilage morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of growth plate cartilage are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060536 ! cartilage morphogenesis +relationship: part_of GO:0003417 ! growth plate cartilage development +created_by: dph +creation_date: 2009-12-22T09:21:30Z + +[Term] +id: GO:0003423 +name: growth plate cartilage chondrocyte division +namespace: biological_process +def: "The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0051301 ! cell division +relationship: part_of GO:0003419 ! growth plate cartilage chondrocyte proliferation +created_by: dph +creation_date: 2009-12-22T09:55:51Z + +[Term] +id: GO:0003424 +name: establishment of cell polarity involved in growth plate cartilage chondrocyte division +namespace: biological_process +def: "The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "growth plate cartilage chondrocyte polarization" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0001736 ! establishment of planar polarity +is_a: GO:0030010 ! establishment of cell polarity +intersection_of: GO:0030010 ! establishment of cell polarity +intersection_of: part_of GO:0003423 ! growth plate cartilage chondrocyte division +relationship: part_of GO:0003423 ! growth plate cartilage chondrocyte division +created_by: dph +creation_date: 2009-12-22T10:18:10Z + +[Term] +id: GO:0003425 +name: establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division +namespace: biological_process +def: "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0000132 ! establishment of mitotic spindle orientation +is_a: GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division +is_a: GO:0090176 ! microtubule cytoskeleton organization involved in establishment of planar polarity +intersection_of: GO:0051294 ! establishment of spindle orientation +intersection_of: part_of GO:0003423 ! growth plate cartilage chondrocyte division +created_by: dph +creation_date: 2009-12-22T10:36:36Z + +[Term] +id: GO:0003426 +name: cytoskeleton polarization involved in growth plate cartilage chondrocyte division +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity +intersection_of: part_of GO:0003424 ! establishment of cell polarity involved in growth plate cartilage chondrocyte division +relationship: part_of GO:0003424 ! establishment of cell polarity involved in growth plate cartilage chondrocyte division +created_by: dph +creation_date: 2009-12-22T11:38:22Z + +[Term] +id: GO:0003427 +name: regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003420 ! regulation of growth plate cartilage chondrocyte proliferation +is_a: GO:0051302 ! regulation of cell division +is_a: GO:0051493 ! regulation of cytoskeleton organization +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +is_a: GO:2000114 ! regulation of establishment of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division +relationship: regulates GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division +created_by: dph +creation_date: 2009-12-22T11:43:29Z + +[Term] +id: GO:0003428 +name: chondrocyte intercalation involved in growth plate cartilage morphogenesis +namespace: biological_process +def: "The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis +relationship: part_of GO:0060029 ! convergent extension involved in organogenesis +created_by: dph +creation_date: 2009-12-22T11:52:32Z + +[Term] +id: GO:0003429 +name: growth plate cartilage chondrocyte morphogenesis +namespace: biological_process +def: "The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003414 ! chondrocyte morphogenesis involved in endochondral bone morphogenesis +is_a: GO:0003422 ! growth plate cartilage morphogenesis +relationship: part_of GO:0003418 ! growth plate cartilage chondrocyte differentiation +created_by: dph +creation_date: 2009-12-22T12:22:24Z + +[Term] +id: GO:0003430 +name: growth plate cartilage chondrocyte growth +namespace: biological_process +def: "The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "growth plate cartilage chondrocyte hypertrophy" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003415 ! chondrocyte hypertrophy +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0003431 ! growth plate cartilage chondrocyte development +created_by: dph +creation_date: 2009-12-22T12:29:19Z + +[Term] +id: GO:0003431 +name: growth plate cartilage chondrocyte development +namespace: biological_process +def: "The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis +relationship: part_of GO:0003418 ! growth plate cartilage chondrocyte differentiation +created_by: dph +creation_date: 2009-12-22T12:32:49Z + +[Term] +id: GO:0003432 +name: cell growth involved in growth plate cartilage chondrocyte morphogenesis +namespace: biological_process +def: "The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003430 ! growth plate cartilage chondrocyte growth +intersection_of: GO:0048588 ! developmental cell growth +intersection_of: part_of GO:0003429 ! growth plate cartilage chondrocyte morphogenesis +relationship: part_of GO:0003429 ! growth plate cartilage chondrocyte morphogenesis +created_by: dph +creation_date: 2009-12-22T12:37:48Z + +[Term] +id: GO:0003433 +name: chondrocyte development involved in endochondral bone morphogenesis +namespace: biological_process +def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0002063 ! chondrocyte development +intersection_of: GO:0002063 ! chondrocyte development +intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis +relationship: part_of GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis +created_by: dph +creation_date: 2009-12-22T12:42:44Z + +[Term] +id: GO:0003434 +name: BMP signaling pathway involved in growth plate cartilage chondrocyte development +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "BMP signalling pathway involved in growth plate cartilage chondrocyte development" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0003431 ! growth plate cartilage chondrocyte development +relationship: part_of GO:0003431 ! growth plate cartilage chondrocyte development +created_by: dph +creation_date: 2009-12-22T12:50:17Z + +[Term] +id: GO:0003435 +name: smoothened signaling pathway involved in growth plate cartilage chondrocyte development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "hedgehog signaling pathway involved in growth plate cartilage chondrocyte development" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in growth plate cartilage chondrocyte development" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway involved in growth plate cartilage chondrocyte development" EXACT [GOC:mah] +is_a: GO:0007224 ! smoothened signaling pathway +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0003431 ! growth plate cartilage chondrocyte development +relationship: part_of GO:0003431 ! growth plate cartilage chondrocyte development +created_by: dph +creation_date: 2009-12-22T01:02:42Z + +[Term] +id: GO:0003436 +name: regulation of cell adhesion involved in growth plate cartilage morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030155 ! regulation of cell adhesion +intersection_of: GO:0030155 ! regulation of cell adhesion +intersection_of: part_of GO:0003422 ! growth plate cartilage morphogenesis +relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis +created_by: dph +creation_date: 2009-12-22T01:28:15Z + +[Term] +id: GO:0003437 +name: regulation of cell communication involved in growth plate cartilage morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +intersection_of: GO:0010646 ! regulation of cell communication +intersection_of: part_of GO:0003422 ! growth plate cartilage morphogenesis +relationship: part_of GO:0003422 ! growth plate cartilage morphogenesis +created_by: dph +creation_date: 2009-12-22T01:34:24Z + +[Term] +id: GO:0003673 +name: obsolete Gene_Ontology +namespace: biological_process +def: "OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "Gene_Ontology" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003674 +name: molecular_function +namespace: molecular_function +alt_id: GO:0005554 +def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt] +comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "molecular function" EXACT [] + +[Term] +id: GO:0003675 +name: obsolete protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003676 +name: nucleic acid binding +namespace: molecular_function +alt_id: GO:0000496 +def: "Interacting selectively and non-covalently with any nucleic acid." [GOC:jl] +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "base pairing" NARROW [] +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0003677 +name: DNA binding +namespace: molecular_function +alt_id: GO:0043566 +def: "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant +subset: goslim_yeast +synonym: "microtubule/chromatin interaction" RELATED [] +synonym: "plasmid binding" NARROW [] +synonym: "structure specific DNA binding" RELATED [] +synonym: "structure-specific DNA binding" RELATED [] +is_a: GO:0003676 ! nucleic acid binding + +[Term] +id: GO:0003678 +name: DNA helicase activity +namespace: molecular_function +alt_id: GO:0003679 +alt_id: GO:0004003 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix." [EC:3.6.4.12, GOC:jl] +synonym: "ATP-dependent DNA helicase activity" EXACT [] +xref: EC:3.6.4.12 +is_a: GO:0004386 ! helicase activity +is_a: GO:0008094 ! DNA-dependent ATPase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0032508 ! DNA duplex unwinding + +[Term] +id: GO:0003680 +name: AT DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA)." [GOC:jl, PMID:2670564] +synonym: "AT binding" EXACT [] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0003681 +name: bent DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA in a bent conformation." [GOC:jl, PMID:12627977] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0003682 +name: chromatin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:jl, ISBN:0198506732, PMID:20404130] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "lamin/chromatin binding" NARROW [] +synonym: "microtubule/chromatin interaction" NARROW [] +synonym: "nuclear membrane vesicle binding to chromatin" NARROW [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0003683 +name: obsolete lamin/chromatin binding +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents two functions. +synonym: "lamin/chromatin binding" EXACT [] +is_obsolete: true +consider: GO:0003682 +consider: GO:0005521 + +[Term] +id: GO:0003684 +name: damaged DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with damaged DNA." [GOC:jl] +synonym: "DNA repair enzyme" RELATED [] +synonym: "DNA repair protein" RELATED [] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0003685 +name: obsolete DNA repair protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it includes a process term. +synonym: "DNA repair protein" EXACT [] +is_obsolete: true +consider: GO:0003684 + +[Term] +id: GO:0003686 +name: obsolete DNA repair enzyme +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it includes a process term. +synonym: "DNA repair enzyme" EXACT [] +is_obsolete: true +consider: GO:0003684 + +[Term] +id: GO:0003687 +name: obsolete DNA replication factor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it does not represent a true molecular function. +synonym: "DNA replication factor" EXACT [] +is_obsolete: true +consider: GO:0006260 + +[Term] +id: GO:0003688 +name: DNA replication origin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally." [GOC:curators] +synonym: "ARS binding" NARROW [] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0003689 +name: DNA clamp loader activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex." [GOC:mah, GOC:vw, PMID:16082778] +synonym: "DNA clamp loading ATPase activity" EXACT [] +synonym: "PCNA loading activity" NARROW [] +synonym: "PCNA loading complex activity" NARROW [] +xref: Reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA" +is_a: GO:0003677 ! DNA binding +is_a: GO:0033170 ! protein-DNA loading ATPase activity + +[Term] +id: GO:0003690 +name: double-stranded DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA." [GOC:elh, GOC:vw] +synonym: "dsDNA binding" EXACT [GOC:elh] +is_a: GO:0003677 ! DNA binding +disjoint_from: GO:0003697 ! single-stranded DNA binding + +[Term] +id: GO:0003691 +name: double-stranded telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded telomere-associated DNA." [GOC:jl, ISBN:0321000382] +is_a: GO:0003690 ! double-stranded DNA binding +is_a: GO:0042162 ! telomeric DNA binding + +[Term] +id: GO:0003692 +name: left-handed Z-DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags." [ISBN:0716720094] +is_a: GO:0003690 ! double-stranded DNA binding + +[Term] +id: GO:0003693 +name: P-element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any P-element, a class of Drosophila transposon responsible for hybrid dysgenesis." [GOC:jl, PMID:9440262] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0003694 +name: obsolete plasmid binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms." [ISBN:0198506732] +comment: This term was made obsolete because it refers to component information. +synonym: "plasmid binding" EXACT [] +synonym: "plasmid-associated protein" RELATED [] +is_obsolete: true +consider: GO:0003677 +consider: GO:0005727 + +[Term] +id: GO:0003695 +name: obsolete random coil DNA binding +namespace: molecular_function +alt_id: GO:0016017 +def: "OBSOLETE. Interacting selectively and non-covalently with DNA in a random coil configuration." [GOC:mah] +comment: This term was obsoleted because the definition was not clear enough as to what is directing specificity of the binding to the DNA. +synonym: "random coil binding" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18879 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0003696 +name: satellite DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA." [GOC:jl, SO:0000005] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0003697 +name: single-stranded DNA binding +namespace: molecular_function +alt_id: GO:0003698 +alt_id: GO:0003699 +def: "Interacting selectively and non-covalently with single-stranded DNA." [GOC:elh, GOC:vw, PMID:22976174] +comment: Note that this term is restricted to those cases where the binding is to a single-stranded DNA molecule, not to one of the stands of double-stranded DNA. +synonym: "ssDNA binding" EXACT [GOC:mah] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0003700 +name: DNA-binding transcription factor activity +namespace: molecular_function +alt_id: GO:0000130 +alt_id: GO:0001071 +alt_id: GO:0001130 +alt_id: GO:0001131 +alt_id: GO:0001151 +alt_id: GO:0001199 +alt_id: GO:0001204 +def: "A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons." [GOC:txnOH-2018] +comment: Curator guidance: Note that most DNA-binding transcription factors do not have enzymatic activity. The presence of specific domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing Myb/SANT and ARID domains, since only a subset of proteins containing these domains are DNA-binding transcription factors for specific genes. +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_plant +subset: goslim_yeast +synonym: "bacterial-type DNA binding transcription factor activity" NARROW [] +synonym: "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity" NARROW [] +synonym: "bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity" NARROW [] +synonym: "bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding" NARROW [] +synonym: "bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding" NARROW [] +synonym: "DNA binding transcription factor activity" EXACT [] +synonym: "gene-specific transcription factor activity" EXACT [] +synonym: "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity" NARROW [] +synonym: "metal ion regulated sequence-specific DNA binding transcription factor activity" NARROW [] +synonym: "nucleic acid binding transcription factor activity" BROAD [] +synonym: "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity" NARROW [] +synonym: "sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "transcription factor activity" BROAD [] +synonym: "transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding" NARROW [] +synonym: "transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding" NARROW [] +synonym: "transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding" NARROW [] +synonym: "transcription factor activity, metal ion regulated sequence-specific DNA binding" NARROW [] +is_a: GO:0140110 ! transcription regulator activity +relationship: has_part GO:0000976 ! transcription regulatory region sequence-specific DNA binding +relationship: part_of GO:0006355 ! regulation of transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15704 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16534 xsd:anyURI +created_by: krc +creation_date: 2010-10-21T04:37:54Z + +[Term] +id: GO:0003701 +name: obsolete RNA polymerase I transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Functions to initiate or regulate RNA polymerase I transcription." [GOC:jl] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "RNA polymerase I transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0001181 +consider: GO:0006360 + +[Term] +id: GO:0003702 +name: obsolete RNA polymerase II transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Functions to initiate or regulate RNA polymerase II transcription." [GOC:jl] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "RNA polymerase II transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0000981 +consider: GO:0006366 + +[Term] +id: GO:0003704 +name: obsolete specific RNA polymerase II transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II." [GOC:ma] +comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "specific RNA polymerase II transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0000981 +consider: GO:0006366 + +[Term] +id: GO:0003706 +name: obsolete ligand-regulated transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand." [GOC:curators] +comment: This term was made obsolete because it does not convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. +synonym: "ligand-regulated transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0004879 +consider: GO:0030374 + +[Term] +id: GO:0003707 +name: steroid hormone receptor activity +namespace: molecular_function +def: "Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function." [GOC:signaling, PMID:14708019] +comment: Some steroid hormone receptors reside in the plasma membrane and signal through second messengers or other intracellular signal transduction pathways. For steroid hormone receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: nuclear receptor activity ; GO:0004879' or nuclear receptor transcription coactivator activity ; GO:0030374'. +is_a: GO:0038023 ! signaling receptor activity +relationship: part_of GO:0043401 ! steroid hormone mediated signaling pathway + +[Term] +id: GO:0003709 +name: obsolete RNA polymerase III transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Functions to initiate or regulate RNA polymerase III transcription." [GOC:jl] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "RNA polymerase III transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0000995 +consider: GO:0006383 + +[Term] +id: GO:0003711 +name: transcription elongation regulator activity +namespace: molecular_function +def: "A molecular function that regulates transcriptional elongation by enabling the transition from transcription initiation to elongation or by altering the elongation properties of the enzyme during the elongation phase of transcription." [GOC:txnOH-2018, PMID:23878398, PMID:28892040] +comment: Restored term from obsolete. +synonym: "transcription elongation factor activity" EXACT [] +synonym: "transcription elongation regulator activity" EXACT [] +synonym: "transcriptional elongation regulator activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14398 xsd:anyURI + +[Term] +id: GO:0003712 +name: transcription coregulator activity +namespace: molecular_function +alt_id: GO:0001104 +alt_id: GO:0016455 +def: "A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator] +comment: Curator guidance: Most transcription coregulators do not bind DNA. Those that do usually bind DNA either in a non-specific or non-direct manner. If a protein binds DNA specifically, consider annotating to GO:0003700 DNA binding transcription factor activity. +subset: goslim_drosophila +synonym: "RNA polymerase II transcriptional cofactor activity" RELATED [] +synonym: "transcription cofactor activity" EXACT [] +synonym: "transcriptional co-regulator" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: part_of GO:1903506 ! regulation of nucleic acid-templated transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15536 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15665 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15998 xsd:anyURI +created_by: krc +creation_date: 2010-11-24T03:02:15Z + +[Term] +id: GO:0003713 +name: transcription coactivator activity +namespace: molecular_function +alt_id: GO:0001105 +def: "A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator." [GOC:txnOH-2018, PMID:10213677, PMID:16858867] +synonym: "RNA polymerase II transcription co-activator activity" RELATED [] +synonym: "RNA polymerase II transcription coactivator activity" RELATED [] +synonym: "RNA polymerase II transcription mediator activity" RELATED [] +synonym: "transcription co-activator activity" EXACT [] +synonym: "transcription coactivator activity" EXACT [] +is_a: GO:0003712 ! transcription coregulator activity +relationship: part_of GO:1903508 ! positive regulation of nucleic acid-templated transcription +property_value: RO:0002161 NCBITaxon:2 +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15665 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15998 xsd:anyURI +created_by: krc +creation_date: 2010-11-24T03:08:19Z + +[Term] +id: GO:0003714 +name: transcription corepressor activity +namespace: molecular_function +alt_id: GO:0001106 +def: "A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867] +synonym: "RNA polymerase II transcription co-repressor activity" RELATED [] +synonym: "RNA polymerase II transcription corepressor activity" RELATED [] +synonym: "transcription co-repressor activity" EXACT [] +synonym: "transcription corepressor activity" EXACT [] +is_a: GO:0003712 ! transcription coregulator activity +relationship: part_of GO:1903507 ! negative regulation of nucleic acid-templated transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15665 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15998 xsd:anyURI +created_by: krc +creation_date: 2010-11-24T03:14:44Z + +[Term] +id: GO:0003715 +name: obsolete transcription termination factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that brings about termination of transcription." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "transcription termination factor activity" EXACT [] +synonym: "transcriptional termination factor activity" EXACT [] +is_obsolete: true +consider: GO:0006353 + +[Term] +id: GO:0003716 +name: obsolete RNA polymerase I transcription termination factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase I." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol I transcription termination factor activity" EXACT [] +synonym: "RNA polymerase I transcription termination factor activity" EXACT [] +is_obsolete: true +consider: GO:0006363 + +[Term] +id: GO:0003717 +name: obsolete RNA polymerase II transcription termination factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase II." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol II transcription termination factor activity" EXACT [] +synonym: "RNA polymerase II transcription termination factor activity" EXACT [] +is_obsolete: true +consider: GO:0006369 + +[Term] +id: GO:0003718 +name: obsolete RNA polymerase III transcription termination factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase III." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol III transcription termination factor activity" EXACT [] +synonym: "RNA polymerase III transcription termination factor activity" EXACT [] +is_obsolete: true +consider: GO:0006386 + +[Term] +id: GO:0003719 +name: obsolete transcription factor binding, cytoplasmic sequestering +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because sequestering is a process rather than a function. +synonym: "transcription factor binding, cytoplasmic sequestering" EXACT [] +is_obsolete: true +replaced_by: GO:0042994 + +[Term] +id: GO:0003720 +name: telomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence." [GOC:krc, PMID:28732250] +xref: Reactome:R-HSA-163090 "Elongation Of The Telomeric Chromosome End" +xref: Reactome:R-HSA-164617 "Elongation of Extended Telomeric Chromosome End" +is_a: GO:0003964 ! RNA-directed DNA polymerase activity + +[Term] +id: GO:0003721 +name: telomerase RNA reverse transcriptase activity +namespace: molecular_function +def: "Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template." [EC:2.7.7.49, PMID:11812242] +synonym: "telomerase, catalyst" EXACT [] +is_a: GO:0003964 ! RNA-directed DNA polymerase activity +relationship: part_of GO:0003720 ! telomerase activity + +[Term] +id: GO:0003723 +name: RNA binding +namespace: molecular_function +alt_id: GO:0000498 +alt_id: GO:0044822 +def: "Interacting selectively and non-covalently with an RNA molecule or a portion thereof." [GOC:jl, GOC:mah] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant +subset: goslim_yeast +synonym: "base pairing with RNA" NARROW [] +synonym: "poly(A) RNA binding" RELATED [] +synonym: "poly(A)-RNA binding" RELATED [] +synonym: "poly-A RNA binding" RELATED [] +xref: Reactome:R-HSA-203922 "Exportin-5 recognizes 3' overhang of pre-miRNA" +is_a: GO:0003676 ! nucleic acid binding + +[Term] +id: GO:0003724 +name: RNA helicase activity +namespace: molecular_function +alt_id: GO:0004004 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix." [EC:3.6.4.13, GOC:jl] +synonym: "ATP-dependent RNA helicase activity" EXACT [] +xref: EC:3.6.4.13 +xref: Reactome:R-HSA-72647 "Cap-bound mRNA is activated by helicases" +is_a: GO:0004386 ! helicase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0003725 +name: double-stranded RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded RNA." [GOC:jl] +synonym: "dsRNA binding" EXACT [GOC:ecd] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0003726 +name: double-stranded RNA adenosine deaminase activity +namespace: molecular_function +alt_id: GO:0003971 +def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule." [GOC:mah] +synonym: "double-stranded RNA specific editase activity" RELATED [] +xref: Reactome:R-HSA-77614 "Deamination at C6 position of adenosine in Editosome (ADAR1)" +xref: Reactome:R-HSA-77615 "Deamination at C6 position of adenosine in Editosome (ADAR2)" +is_a: GO:0004000 ! adenosine deaminase activity + +[Term] +id: GO:0003727 +name: single-stranded RNA binding +namespace: molecular_function +alt_id: GO:0003728 +def: "Interacting selectively and non-covalently with single-stranded RNA." [GOC:jl] +synonym: "ssRNA binding" EXACT [GOC:mah] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0003729 +name: mRNA binding +namespace: molecular_function +alt_id: GO:0000499 +def: "Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns." [GOC:kmv, GOC:pr, SO:0000234] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "base pairing with mRNA" NARROW [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0003730 +name: mRNA 3'-UTR binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule." [GOC:mah] +synonym: "mRNA 3' UTR binding" EXACT [] +is_a: GO:0003729 ! mRNA binding + +[Term] +id: GO:0003731 +name: obsolete mRNA cap binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript." [GOC:mah] +comment: This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to. +synonym: "mRNA cap binding" EXACT [] +is_obsolete: true +consider: GO:0000339 + +[Term] +id: GO:0003732 +name: obsolete snRNA cap binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule." [GOC:mah] +comment: This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to. +synonym: "snRNA cap binding" EXACT [] +is_obsolete: true +consider: GO:0000339 + +[Term] +id: GO:0003733 +name: obsolete ribonucleoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a cellular component rather than a molecular function. +synonym: "ribonucleoprotein" EXACT [] +is_obsolete: true +replaced_by: GO:1990904 + +[Term] +id: GO:0003734 +name: obsolete small nuclear ribonucleoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a cellular component rather than a molecular function. +synonym: "small nuclear ribonucleoprotein" EXACT [] +synonym: "snRNP" EXACT [] +is_obsolete: true +replaced_by: GO:0030532 + +[Term] +id: GO:0003735 +name: structural constituent of ribosome +namespace: molecular_function +alt_id: GO:0003736 +alt_id: GO:0003737 +alt_id: GO:0003738 +alt_id: GO:0003739 +alt_id: GO:0003740 +alt_id: GO:0003741 +alt_id: GO:0003742 +def: "The action of a molecule that contributes to the structural integrity of the ribosome." [GOC:mah] +comment: Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_yeast +synonym: "ribosomal protein" BROAD [] +synonym: "ribosomal RNA" RELATED [] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0005840 ! ribosome +relationship: occurs_in GO:0005840 ! ribosome + +[Term] +id: GO:0003743 +name: translation initiation factor activity +namespace: molecular_function +alt_id: GO:0003744 +alt_id: GO:0003745 +def: "Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide." [ISBN:0198506732] +xref: Reactome:R-HSA-72621 "Ribosomal scanning" +xref: Reactome:R-HSA-72697 "Start codon recognition" +xref: Reactome:R-HSA-72722 "eIF2 activation" +is_a: GO:0008135 ! translation factor activity, RNA binding +relationship: part_of GO:0006413 ! translational initiation + +[Term] +id: GO:0003746 +name: translation elongation factor activity +namespace: molecular_function +alt_id: GO:0008182 +alt_id: GO:0008183 +def: "Functions in chain elongation during polypeptide synthesis at the ribosome." [ISBN:0198506732] +xref: Reactome:R-HSA-192704 "Synthesis of PB1-F2" +xref: Reactome:R-HSA-192841 "Viral Protein Synthesis" +is_a: GO:0008135 ! translation factor activity, RNA binding +relationship: part_of GO:0006414 ! translational elongation + +[Term] +id: GO:0003747 +name: translation release factor activity +namespace: molecular_function +alt_id: GO:0003748 +alt_id: GO:0003749 +def: "Involved in catalyzing the release of a nascent polypeptide chain from a ribosome." [ISBN:0198547684] +is_a: GO:0008079 ! translation termination factor activity + +[Term] +id: GO:0003750 +name: obsolete cell cycle regulator +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it does not represent a single molecular function. +synonym: "cell cycle regulator" EXACT [] +is_obsolete: true +replaced_by: GO:0051726 + +[Term] +id: GO:0003754 +name: obsolete chaperone activity +namespace: molecular_function +alt_id: GO:0003757 +alt_id: GO:0003758 +alt_id: GO:0003760 +alt_id: GO:0003761 +def: "OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function." [ISBN:0198547684] +comment: This term was made obsolete because, as defined, it represents a class of gene products rather than a molecular function. The term string is also ambiguous, having connotations of involvement in transport processes. +synonym: "chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0044183 +consider: GO:0051082 + +[Term] +id: GO:0003755 +name: peptidyl-prolyl cis-trans isomerase activity +namespace: molecular_function +alt_id: GO:0004752 +alt_id: GO:0042028 +def: "Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0)." [EC:5.2.1.8] +synonym: "cis-trans proline isomerase activity" EXACT [] +synonym: "cyclophilin activity" RELATED [EC:5.2.1.8] +synonym: "cyclophilin-type peptidyl-prolyl cis-trans isomerase activity" NARROW [] +synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" NARROW [] +synonym: "immunophilin" RELATED [] +synonym: "juglone-sensitive cis-trans proline isomerase activity" NARROW [GOC:mah] +synonym: "juglone-sensitive peptidyl-prolyl cis-trans isomerase activity" NARROW [GOC:mah] +synonym: "parvulin" RELATED [] +synonym: "peptide bond isomerase activity" EXACT [EC:5.2.1.8] +synonym: "peptidyl-prolyl isomerase B reaction" RELATED [] +synonym: "peptidylproline cis-trans-isomerase activity" EXACT [EC:5.2.1.8] +synonym: "peptidylprolyl cis-trans isomerase activity" EXACT [EC:5.2.1.8] +synonym: "peptidylprolyl isomerase activity" EXACT [EC:5.2.1.8] +synonym: "PPIase activity" EXACT [EC:5.2.1.8] +synonym: "rotamase activity" EXACT [EC:5.2.1.8] +xref: EC:5.2.1.8 +xref: MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN +xref: Reactome:R-HSA-2022073 "Procollagen triple helix formation" +xref: Reactome:R-HSA-9626816 "PIN1 binds p-S345-NCF1" +is_a: GO:0016859 ! cis-trans isomerase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0000413 ! protein peptidyl-prolyl isomerization + +[Term] +id: GO:0003756 +name: protein disulfide isomerase activity +namespace: molecular_function +alt_id: GO:0006467 +def: "Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins." [EC:5.3.4.1, GOC:vw, Wikipedia:Protein_disulfide-isomerase#Function] +synonym: "disulphide bond biosynthesis" EXACT [] +synonym: "disulphide bond formation" EXACT [] +synonym: "protein cysteine-thiol oxidation" RELATED [] +synonym: "protein disulfide-isomerase" BROAD [EC:5.3.4.1] +synonym: "protein disulfide-isomerase reaction" EXACT [EC:5.3.4.1] +synonym: "protein disulphide isomerase activity" EXACT [] +synonym: "protein thiol-disulfide exchange" EXACT [] +synonym: "protein thiol-disulphide exchange" EXACT [] +synonym: "S-S rearrangase activity" RELATED [EC:5.3.4.1] +xref: EC:5.3.4.1 +xref: MetaCyc:5.3.4.1-RXN +xref: Reactome:R-HSA-8950113 "IL12A binds IL12B" +xref: Reactome:R-HSA-8950183 "IL12B binds IL23A" +xref: Reactome:R-HSA-8950456 "IL12B dimerizes" +is_a: GO:0016864 ! intramolecular oxidoreductase activity, transposing S-S bonds +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0003759 +name: obsolete glycoprotein-specific chaperone activity +namespace: molecular_function +def: "OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins." [GOC:jl, PMID:11337494] +comment: This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. +synonym: "glycoprotein-specific chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0044183 +consider: GO:0051082 + +[Term] +id: GO:0003762 +name: obsolete histone-specific chaperone activity +namespace: molecular_function +def: "OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function." [GOC:jl, PMID:7600578, PMID:9325046] +comment: This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. +synonym: "histone-specific chaperone activity" EXACT [] +synonym: "nucleosome assembly chaperone" EXACT [] +is_obsolete: true +consider: GO:0006333 +consider: GO:0006334 +consider: GO:0034728 +consider: GO:0042393 +consider: GO:0043486 +consider: GO:0044183 +consider: GO:0051082 + +[Term] +id: GO:0003763 +name: obsolete chaperonin ATPase activity +namespace: molecular_function +alt_id: GO:0003764 +alt_id: GO:0003765 +alt_id: GO:0003766 +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts." [EC:3.6.4.9, ISBN:0198547684] +comment: This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. +synonym: "chaperonin" EXACT [] +synonym: "chaperonin ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016887 +consider: GO:0006457 + +[Term] +id: GO:0003767 +name: obsolete co-chaperone activity +namespace: molecular_function +alt_id: GO:0003768 +alt_id: GO:0003769 +alt_id: GO:0003770 +alt_id: GO:0003771 +def: "OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity." [GOC:rb] +comment: This term was made obsolete because it represents a class of gene products rather than a molecular function. +synonym: "co-chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0044183 +consider: GO:0051087 + +[Term] +id: GO:0003772 +name: obsolete co-chaperonin activity +namespace: molecular_function +def: "OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity." [GOC:rb] +comment: This term was made obsolete because it represents a class of gene products rather than a molecular function. +synonym: "co-chaperonin activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0044183 +consider: GO:0051087 + +[Term] +id: GO:0003773 +name: obsolete heat shock protein activity +namespace: molecular_function +def: "OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones." [ISBN:0198547684] +comment: This term was made obsolete because it represents a class of gene products rather than a molecular function. +synonym: "heat shock protein activity" EXACT [] +is_obsolete: true +consider: GO:0006986 +consider: GO:0042026 + +[Term] +id: GO:0003774 +name: motor activity +namespace: molecular_function +def: "Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate." [GOC:mah, GOC:vw, ISBN:0815316194, PMID:11242086] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +subset: goslim_plant +xref: Reactome:R-HSA-1861595 "Extension of pseudopodia by myosin-X in a PI3K dependent manner" +is_a: GO:0017111 ! nucleoside-triphosphatase activity + +[Term] +id: GO:0003775 +name: obsolete axonemal motor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it includes cellular component information. +synonym: "axonemal motor activity" EXACT [] +is_obsolete: true +consider: GO:0003777 +consider: GO:0005930 + +[Term] +id: GO:0003776 +name: obsolete muscle motor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it includes anatomy information. +synonym: "muscle motor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0000146 +consider: GO:0006936 +consider: GO:0043292 + +[Term] +id: GO:0003777 +name: microtubule motor activity +namespace: molecular_function +def: "Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)." [GOC:mah, ISBN:0815316194] +comment: Consider also annotating to the molecular function term 'microtubule binding ; GO:0008017'. +synonym: "axonemal motor activity" NARROW [] +synonym: "dynein" BROAD [] +synonym: "dynein ATPase activity" NARROW [] +synonym: "kinesin" BROAD [] +synonym: "kinesin motor activity" NARROW [] +synonym: "kinetochore motor activity" NARROW [] +xref: Reactome:R-HSA-177479 "Axonal transport of NGF:Trk complexes" +xref: Reactome:R-HSA-265160 "Insulin secretory granule translocates to cell cortex" +is_a: GO:0003774 ! motor activity + +[Term] +id: GO:0003778 +name: obsolete dynactin motor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:hjd] +comment: This term was made obsolete because the dynactin complex is not a motor as such, but does regulate the dynein motor complex. +synonym: "dynactin motor" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003779 +name: actin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments." [GOC:clt] +synonym: "membrane associated actin binding" NARROW [] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0003780 +name: obsolete actin cross-linking activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with two actin filaments to anchor them together." [GOC:jid] +comment: This term was made obsolete because it represents a combination of molecular functions. +synonym: "actin cross-linking activity" EXACT [] +is_obsolete: true +consider: GO:0030674 +consider: GO:0051015 + +[Term] +id: GO:0003781 +name: obsolete actin bundling activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a biological process. +synonym: "actin bundling activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051017 + +[Term] +id: GO:0003782 +name: obsolete F-actin capping activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a biological process. +synonym: "F-actin capping activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051016 + +[Term] +id: GO:0003783 +name: obsolete barbed-end actin capping activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a biological process. +synonym: "barbed-end actin capping activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051016 + +[Term] +id: GO:0003784 +name: obsolete barbed-end actin capping/severing activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes two biological processes. +synonym: "barbed-end actin capping/severing activity" EXACT [] +is_obsolete: true +consider: GO:0051014 +consider: GO:0051016 + +[Term] +id: GO:0003785 +name: actin monomer binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with monomeric actin, also known as G-actin." [GOC:ai] +synonym: "G actin binding" EXACT [] +is_a: GO:0003779 ! actin binding + +[Term] +id: GO:0003786 +name: actin lateral binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an actin filament along its length." [GOC:mah] +is_a: GO:0051015 ! actin filament binding + +[Term] +id: GO:0003787 +name: obsolete actin depolymerizing activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a biological process. +synonym: "actin depolymerizing activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030042 + +[Term] +id: GO:0003788 +name: obsolete actin monomer sequestering activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because sequestering is a process, not an activity. +synonym: "actin monomer sequestering activity" EXACT [] +is_obsolete: true +replaced_by: GO:0042989 + +[Term] +id: GO:0003789 +name: obsolete actin filament severing activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a biological process. +synonym: "actin filament severing activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051014 + +[Term] +id: GO:0003790 +name: obsolete actin modulating activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not make sense. +synonym: "actin modulating activity" EXACT [] +is_obsolete: true +consider: GO:0030036 + +[Term] +id: GO:0003791 +name: obsolete membrane associated actin binding +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "membrane associated actin binding" EXACT [] +is_obsolete: true +consider: GO:0003779 +consider: GO:0016020 + +[Term] +id: GO:0003792 +name: obsolete regulation of actin thin filament length activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the term belongs in the process ontology. +synonym: "regulation of actin thin filament length activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030832 + +[Term] +id: GO:0003793 +name: obsolete defense/immunity protein activity +namespace: molecular_function +def: "OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease." [GOC:go_curators] +comment: This term was made obsolete because it refers to involvement in a biological process. +synonym: "defence/immunity protein activity" EXACT [] +synonym: "defense/immunity protein activity" EXACT [] +is_obsolete: true +consider: GO:0006952 + +[Term] +id: GO:0003794 +name: obsolete acute-phase response protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to involvement in a biological process. +synonym: "acute-phase response protein activity" EXACT [] +is_obsolete: true +consider: GO:0006953 + +[Term] +id: GO:0003795 +name: obsolete antimicrobial peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, microbial cells." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "antimicrobial peptide activity" EXACT [] +is_obsolete: true +consider: GO:0019730 + +[Term] +id: GO:0003796 +name: lysozyme activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan." [EC:3.2.1.17, PMID:22748813] +synonym: "1,4-N-acetylmuramidase activity" EXACT [] +synonym: "globulin G" RELATED [EC:3.2.1.17] +synonym: "globulin G1" RELATED [EC:3.2.1.17] +synonym: "L-7001" RELATED [EC:3.2.1.17] +synonym: "lysozyme g" RELATED [EC:3.2.1.17] +synonym: "mucopeptide glucohydrolase activity" EXACT [] +synonym: "mucopeptide N-acetylmuramoylhydrolase activity" EXACT [] +synonym: "muramidase activity" EXACT [] +synonym: "N,O-diacetylmuramidase activity" EXACT [] +synonym: "peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [EC:3.2.1.17] +synonym: "PR1-lysozyme" RELATED [EC:3.2.1.17] +xref: EC:3.2.1.17 +xref: MetaCyc:3.2.1.17-RXN +xref: Reactome:R-HSA-8862320 "LYZ hydrolyzes peptidoglycans in the bacterial cell wall" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +is_a: GO:0061783 ! peptidoglycan muralytic activity + +[Term] +id: GO:0003797 +name: obsolete antibacterial peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "antibacterial peptide activity" EXACT [] +is_obsolete: true +consider: GO:0042742 + +[Term] +id: GO:0003798 +name: obsolete male-specific antibacterial peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "male-specific antibacterial peptide activity" EXACT [] +is_obsolete: true +consider: GO:0050831 + +[Term] +id: GO:0003799 +name: obsolete antifungal peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, fungal cells." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "antifungal peptide activity" EXACT [] +is_obsolete: true +consider: GO:0050832 + +[Term] +id: GO:0003800 +name: obsolete antiviral response protein activity +namespace: molecular_function +def: "OBSOLETE. A protein involved in an antiviral response." [GOC:ai] +comment: This term was made obsolete because it refers to involvement in a biological process. +synonym: "antiviral response protein activity" EXACT [] +is_obsolete: true +consider: GO:0009615 + +[Term] +id: GO:0003801 +name: obsolete blood coagulation factor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to involvement in a biological process. +synonym: "blood coagulation factor activity" EXACT [] +is_obsolete: true +consider: GO:0004252 +consider: GO:0007596 + +[Term] +id: GO:0003802 +name: obsolete coagulation factor VIIa activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta." [EC:3.4.21.21, PMID:12496253] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood coagulation factor VII" RELATED [EC:3.4.21.21] +synonym: "blood coagulation factor VII activity" EXACT [] +synonym: "blood-coagulation factor VIIa" RELATED [EC:3.4.21.21] +synonym: "coagulation factor VIIa activity" EXACT [] +xref: EC:3.4.21.21 +xref: MetaCyc:3.4.21.21-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003803 +name: obsolete coagulation factor IXa activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa." [EC:3.4.21.22] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood coagulation factor XI" RELATED [EC:3.4.21.22] +synonym: "activated blood-coagulation factor IX" RELATED [EC:3.4.21.22] +synonym: "activated christmas factor" RELATED [EC:3.4.21.22] +synonym: "autoprothrombin II" RELATED [EC:3.4.21.22] +synonym: "blood coagulation factor IX activity" EXACT [] +synonym: "blood platelet cofactor II" RELATED [EC:3.4.21.22] +synonym: "blood-coagulation factor IXa" RELATED [EC:3.4.21.22] +synonym: "Christmas factor activity" EXACT [EC:3.4.21.22] +synonym: "coagulation factor IXa activity" EXACT [] +xref: EC:3.4.21.22 +xref: MetaCyc:3.4.21.22-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003804 +name: obsolete coagulation factor Xa activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa)." [EC:3.4.21.6, GOC:jl, PMID:7354023] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood-coagulation factor X" RELATED [EC:3.4.21.6] +synonym: "activated factor X" RELATED [EC:3.4.21.6] +synonym: "activated Stuart-Prower factor" RELATED [EC:3.4.21.6] +synonym: "autoprothrombin C" RELATED [EC:3.4.21.6] +synonym: "blood coagulation factor X activity" EXACT [] +synonym: "coagulation factor Xa activity" EXACT [] +synonym: "factor Xa" RELATED [EC:3.4.21.6] +synonym: "plasma thromboplastin" RELATED [EC:3.4.21.6] +synonym: "prothrombase activity" EXACT [EC:3.4.21.6] +synonym: "prothrombinase activity" EXACT [EC:3.4.21.6] +synonym: "Stuart factor" RELATED [EC:3.4.21.6] +synonym: "Stuart factor activity" EXACT [EC:3.4.21.6] +synonym: "thrombokinase activity" EXACT [EC:3.4.21.6] +synonym: "thromboplastin" RELATED [EC:3.4.21.6] +xref: EC:3.4.21.6 +xref: MetaCyc:3.4.21.6-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003805 +name: obsolete coagulation factor XIa activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa." [EC:3.4.21.27] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood-coagulation factor XI" RELATED [EC:3.4.21.27] +synonym: "activated plasma thromboplastin antecedent" RELATED [EC:3.4.21.27] +synonym: "blood coagulation factor XI activity" EXACT [] +synonym: "blood-coagulation factor XIa" RELATED [EC:3.4.21.27] +synonym: "coagulation factor XIa activity" EXACT [] +synonym: "plasma thromboplastin antecedent activity" EXACT [EC:3.4.21.27] +xref: EC:3.4.21.27 +xref: MetaCyc:3.4.21.27-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003806 +name: obsolete coagulation factor XIIa activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa." [EC:3.4.21.38] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated beta blood-coagulation factor XII" RELATED [EC:3.4.21.38] +synonym: "blood coagulation factor XII activity" EXACT [] +synonym: "blood-coagulation factor XIIabeta" RELATED [EC:3.4.21.38] +synonym: "blood-coagulation factor XIIf" RELATED [EC:3.4.21.38] +synonym: "coagulation factor XIIa activity" EXACT [] +synonym: "hageman factor (activated)" RELATED [EC:3.4.21.38] +synonym: "hageman factor activity" EXACT [EC:3.4.21.38] +synonym: "hageman factor beta-fragment" RELATED [EC:3.4.21.38] +synonym: "hageman factor fragment HFf" RELATED [EC:3.4.21.38] +synonym: "kallikreinogen activator" RELATED [EC:3.4.21.38] +synonym: "prealbumin activator" RELATED [EC:3.4.21.38] +synonym: "prekallikrein activator" RELATED [EC:3.4.21.38] +xref: EC:3.4.21.38 +xref: MetaCyc:3.4.21.38-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003807 +name: obsolete plasma kallikrein activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin." [EC:3.4.21.34] +comment: This term was made obsolete because it represents a gene product. +synonym: "bradykininogenase" BROAD [EC:3.4.21.34] +synonym: "callicrein" RELATED [EC:3.4.21.34] +synonym: "depot-padutin" RELATED [EC:3.4.21.34] +synonym: "dilminal D" RELATED [EC:3.4.21.34] +synonym: "glumorin" RELATED [EC:3.4.21.34] +synonym: "kallidinogenase" BROAD [EC:3.4.21.34] +synonym: "kallikrein" RELATED [EC:3.4.21.34] +synonym: "kallikrein I" RELATED [EC:3.4.21.34] +synonym: "kallikrein II" RELATED [EC:3.4.21.34] +synonym: "kininogenase" BROAD [EC:3.4.21.34] +synonym: "kininogenin activity" RELATED [EC:3.4.21.34] +synonym: "onokrein P" RELATED [EC:3.4.21.34] +synonym: "padreatin" RELATED [EC:3.4.21.34] +synonym: "padutin" RELATED [EC:3.4.21.34] +synonym: "panceatic kallikrein" RELATED [EC:3.4.21.34] +synonym: "plasma kallikrein activity" EXACT [] +synonym: "serum kallikrein activity" EXACT [EC:3.4.21.34] +synonym: "urinary kallikrein" RELATED [EC:3.4.21.34] +synonym: "urokallikrein" RELATED [EC:3.4.21.34] +xref: EC:3.4.21.34 +xref: MetaCyc:3.4.21.34-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003808 +name: obsolete protein C (activated) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the degradation of blood coagulation factors Va and VIIIa." [EC:3.4.21.69] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood coagulation factor XIV activity" EXACT [EC:3.4.21.69] +synonym: "activated protein C" RELATED [EC:3.4.21.69] +synonym: "autoprothrombin II-A" RELATED [EC:3.4.21.69] +synonym: "autoprothrombin IIA activity" EXACT [EC:3.4.21.69] +synonym: "blood-coagulation factor XIVa" RELATED [EC:3.4.21.69] +synonym: "GSAPC" RELATED [EC:3.4.21.69] +synonym: "protein C (activated) activity" EXACT [] +synonym: "protein Ca" RELATED [EC:3.4.21.69] +xref: EC:3.4.21.69 +xref: MetaCyc:3.4.21.69-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003809 +name: obsolete thrombin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B." [EC:3.4.21.5] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated blood-coagulation factor II" RELATED [EC:3.4.21.5] +synonym: "beta-thrombin" RELATED [EC:3.4.21.5] +synonym: "blood-coagulation factor IIa" RELATED [EC:3.4.21.5] +synonym: "E thrombin" RELATED [EC:3.4.21.5] +synonym: "factor IIa" RELATED [EC:3.4.21.5] +synonym: "fibrinogenase activity" EXACT [EC:3.4.21.5] +synonym: "gamma-thrombin" RELATED [EC:3.4.21.5] +synonym: "thrombase activity" EXACT [EC:3.4.21.5] +synonym: "thrombin activity" EXACT [] +synonym: "thrombin-C" RELATED [EC:3.4.21.5] +synonym: "thrombofort" RELATED [EC:3.4.21.5] +synonym: "topical" RELATED [EC:3.4.21.5] +synonym: "tropostasin" RELATED [EC:3.4.21.5] +xref: EC:3.4.21.5 +xref: MetaCyc:3.4.21.5-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003810 +name: protein-glutamine gamma-glutamyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links." [EC:2.3.2.13, RESID:AA0124] +synonym: "factor XIIIa" RELATED [EC:2.3.2.13] +synonym: "fibrin stabilizing factor" RELATED [EC:2.3.2.13] +synonym: "fibrinoligase activity" EXACT [] +synonym: "glutaminylpeptide gamma-glutamyltransferase activity" EXACT [EC:2.3.2.13] +synonym: "polyamine transglutaminase activity" RELATED [EC:2.3.2.13] +synonym: "protein-glutamine:amine gamma-glutamyltransferase" EXACT [EC:2.3.2.13] +synonym: "R-glutaminyl-peptide:amine gamma-glutamyl transferase activity" EXACT [EC:2.3.2.13] +synonym: "TGase activity" EXACT [] +synonym: "tissue transglutaminase" NARROW [EC:2.3.2.13] +synonym: "transglutaminase activity" EXACT [] +xref: EC:2.3.2.13 +xref: MetaCyc:2.3.2.13-RXN +xref: Reactome:R-HSA-140851 "fibrin multimer -> fibrin multimer, crosslinked + NH4+" +xref: Reactome:R-HSA-6810894 "Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking" +xref: RESID:AA0124 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0003811 +name: obsolete complement activity +namespace: molecular_function +def: "OBSOLETE. Any of a set of activities involved in the complement cascade." [GOC:jl] +comment: This term was made obsolete because it refers to involvement in a biological process. +synonym: "complement activity" EXACT [] +is_obsolete: true +consider: GO:0006956 + +[Term] +id: GO:0003812 +name: obsolete alternative-complement-pathway C3/C5 convertase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b." [EC:3.4.21.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "(C3b)n,Bb" RELATED [EC:3.4.21.47] +synonym: "(CVF)-dependent glycine-rich-beta-glucoprotein" RELATED [EC:3.4.21.47] +synonym: "alternative complement pathway C3(C5) convertase activity" EXACT [EC:3.4.21.47] +synonym: "alternative-complement-pathway C3/C5 convertase activity" EXACT [] +synonym: "C3 convertase activity" BROAD [EC:3.4.21.47] +synonym: "C3 proactivator" RELATED [EC:3.4.21.47] +synonym: "C3b,Bb,CVF,Bb,C5 convertase activity" EXACT [EC:3.4.21.47] +synonym: "C5 convertase activity" BROAD [EC:3.4.21.47] +synonym: "cobra venom factor-dependent C3 convertase" NARROW [EC:3.4.21.47] +synonym: "complement C 3(C 5) convertase (amplification)" EXACT [EC:3.4.21.47] +synonym: "complement component C3/C5 convertase (alternative) activity" EXACT [EC:3.4.21.47] +synonym: "complement factor B activity" EXACT [EC:3.4.21.47] +synonym: "CVF,Bb" RELATED [EC:3.4.21.47] +synonym: "glycine-rich beta-glycoprotein" RELATED [EC:3.4.21.47] +synonym: "heat-labile factor" RELATED [EC:3.4.21.47] +synonym: "proenzyme factor B" EXACT [] +synonym: "properdin factor B activity" EXACT [EC:3.4.21.47] +xref: EC:3.4.21.47 +xref: MetaCyc:3.4.21.47-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003813 +name: obsolete classical-complement-pathway C3/C5 convertase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b." [EC:3.4.21.43] +comment: This term was made obsolete because it represents a gene product. +synonym: "C3 convertase activity" BROAD [EC:3.4.21.43] +synonym: "C42" RELATED [EC:3.4.21.43] +synonym: "C423" RELATED [EC:3.4.21.43] +synonym: "C4b,2a" RELATED [EC:3.4.21.43] +synonym: "C4b,2a,3b" RELATED [EC:3.4.21.43] +synonym: "C5 convertase activity" BROAD [EC:3.4.21.43] +synonym: "classical-complement-pathway C3/C5 convertase activity" EXACT [] +synonym: "complement C2 activity" BROAD [EC:3.4.21.43] +synonym: "complement C3 convertase activity" EXACT [EC:3.4.21.43] +synonym: "complement C42" RELATED [EC:3.4.21.43] +xref: EC:3.4.21.43 +xref: MetaCyc:3.4.21.43-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003815 +name: obsolete complement component C1r activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42)." [EC:3.4.21.41] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated complement C1r" RELATED [EC:3.4.21.41] +synonym: "C1r esterase activity" EXACT [EC:3.4.21.41] +synonym: "complement component C1r activity" EXACT [] +synonym: "complement subcomponent C1r" RELATED [EC:3.4.21.41] +xref: EC:3.4.21.41 +xref: MetaCyc:3.4.21.41-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003816 +name: obsolete complement component C1s activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond)." [EC:3.4.21.42] +comment: This term was made obsolete because it represents a gene product. +synonym: "activated complement C1s" RELATED [EC:3.4.21.42] +synonym: "C1 esterase activity" EXACT [EC:3.4.21.42] +synonym: "C1s esterase activity" EXACT [EC:3.4.21.42] +synonym: "complement C1s" RELATED [EC:3.4.21.42] +synonym: "complement component C1s activity" EXACT [] +synonym: "complement subcomponent C1s" RELATED [EC:3.4.21.42] +xref: EC:3.4.21.42 +xref: MetaCyc:3.4.21.42-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003817 +name: obsolete complement factor D activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF)." [EC:3.4.21.46] +comment: This term was made obsolete because it represents a gene product. +synonym: "adipsin" EXACT [] +synonym: "C3 convertase activator activity" EXACT [EC:3.4.21.46] +synonym: "C3 proactivator convertase activity" EXACT [EC:3.4.21.46] +synonym: "complement factor D activity" EXACT [] +synonym: "factor D" RELATED [EC:3.4.21.46] +synonym: "factor D (complement)" RELATED [EC:3.4.21.46] +synonym: "properdin factor D esterase activity" EXACT [EC:3.4.21.46] +xref: EC:3.4.21.46 +xref: MetaCyc:3.4.21.46-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003818 +name: obsolete complement factor I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage." [EC:3.4.21.45] +comment: This term was made obsolete because it represents a gene product. +synonym: "C3b inactivator activity" NARROW [EC:3.4.21.45] +synonym: "C3b/C4b inactivator activity" EXACT [EC:3.4.21.45] +synonym: "C3bINA" RELATED [EC:3.4.21.45] +synonym: "complement C3b inactivator" RELATED [EC:3.4.21.45] +synonym: "complement C3b/C4b inactivator" RELATED [EC:3.4.21.45] +synonym: "complement C4b inactivator" RELATED [EC:3.4.21.45] +synonym: "complement C4bi" RELATED [EC:3.4.21.45] +synonym: "complement component C3b inactivator activity" EXACT [EC:3.4.21.45] +synonym: "complement factor I activity" EXACT [] +synonym: "conglutinogen-activating factor C" RELATED [EC:3.4.21.45] +synonym: "factor I" RELATED [EC:3.4.21.45] +xref: EC:3.4.21.45 +xref: MetaCyc:3.4.21.45-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0003819 +name: obsolete major histocompatibility complex antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "major histocompatibility complex antigen" EXACT [] +synonym: "MHC protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003820 +name: obsolete class I major histocompatibility complex antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "class I major histocompatibility complex antigen" EXACT [] +is_obsolete: true +consider: GO:0042612 + +[Term] +id: GO:0003821 +name: obsolete class II major histocompatibility complex antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "class II major histocompatibility complex antigen" EXACT [] +is_obsolete: true +consider: GO:0042613 + +[Term] +id: GO:0003822 +name: obsolete MHC-interacting protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "MHC-interacting protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003823 +name: antigen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen." [GOC:jl, ISBN:0198506732, ISBN:0721662544] +subset: goslim_chembl +subset: goslim_pir +synonym: "antibody" RELATED [] +synonym: "B cell receptor activity" RELATED [] +synonym: "immunoglobulin" RELATED [] +synonym: "opsonin activity" RELATED [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0003824 +name: catalytic activity +namespace: molecular_function +def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] +xref: Wikipedia:Enzyme +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0003825 +name: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate." [EC:2.4.1.15] +synonym: "alpha,alpha-trehalose phosphate synthase (UDP-forming)" EXACT [EC:2.4.1.15] +synonym: "phosphotrehalose-uridine diphosphate transglucosylase activity" EXACT [EC:2.4.1.15] +synonym: "transglucosylase activity" EXACT [] +synonym: "trehalose 6-phosphate synthase activity" EXACT [] +synonym: "trehalose 6-phosphate synthetase activity" EXACT [] +synonym: "trehalose phosphate synthase activity" EXACT [EC:2.4.1.15] +synonym: "trehalose phosphate synthetase activity" EXACT [EC:2.4.1.15] +synonym: "trehalose phosphate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] +synonym: "trehalose-P synthetase activity" EXACT [EC:2.4.1.15] +synonym: "trehalose-phosphate synthase activity" EXACT [] +synonym: "trehalose-phosphate synthetase activity" EXACT [] +synonym: "trehalosephosphate-UDP glucosyl transferase activity" EXACT [] +synonym: "trehalosephosphate-UDP glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose-glucose-phosphate glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose-glucosephosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] +synonym: "UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [] +synonym: "UDPglucose-glucose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] +synonym: "UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.15] +synonym: "uridine diphosphoglucose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] +xref: EC:2.4.1.15 +xref: MetaCyc:TREHALOSE6PSYN-RXN +xref: RHEA:18889 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0003826 +name: alpha-ketoacid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction involving an alpha-ketoacid." [GOC:mah] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0003827 +name: alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP." [EC:2.4.1.101, RHEA:11456] +synonym: "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] +synonym: "alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] +synonym: "alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "GnTI" RELATED [EC:2.4.1.101] +synonym: "GNTI activity" EXACT [EC:2.4.1.101] +synonym: "N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] +synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] +synonym: "UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.101] +synonym: "UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] +synonym: "UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] +synonym: "uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] +xref: EC:2.4.1.101 +xref: KEGG_REACTION:R05983 +xref: MetaCyc:2.4.1.101-RXN +xref: Reactome:R-HSA-964768 "Addition of GlcNAc to the glycan on the A arm" +xref: RHEA:11456 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0003828 +name: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R." [EC:2.4.99.8] +synonym: "alpha-2,8-sialyltransferase activity" EXACT [EC:2.4.99.8] +synonym: "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity" EXACT [] +synonym: "CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.8] +synonym: "CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity" EXACT [EC:2.4.99.8] +synonym: "CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity" EXACT [EC:2.4.99.8] +synonym: "cytidine monophosphoacetylneuraminate-ganglioside GM3" RELATED [EC:2.4.99.8] +synonym: "ganglioside GD3 synthase activity" EXACT [EC:2.4.99.8] +synonym: "ganglioside GD3 synthetase sialyltransferase activity" EXACT [EC:2.4.99.8] +synonym: "GD3 synthase activity" EXACT [EC:2.4.99.8] +synonym: "SAT-2" RELATED [EC:2.4.99.8] +xref: EC:2.4.99.8 +xref: MetaCyc:2.4.99.8-RXN +xref: Reactome:R-HSA-1022133 "ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans" +xref: Reactome:R-HSA-4084978 "ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues" +xref: Reactome:R-HSA-422454 "Polysialylation of NCAM1" +xref: RHEA:19313 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0003829 +name: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R." [EC:2.4.1.102] +synonym: "beta(6)-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] +synonym: "beta6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] +synonym: "core 2 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] +synonym: "core 6-beta-GlcNAc-transferase A" RELATED [EC:2.4.1.102] +synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.102] +synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.102] +synonym: "uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] +synonym: "uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] +xref: EC:2.4.1.102 +xref: MetaCyc:2.4.1.102-RXN +xref: Reactome:R-HSA-914012 "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins" +xref: Reactome:R-HSA-914018 "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein" +xref: RHEA:18705 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0003830 +name: beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R." [EC:2.4.1.144] +synonym: "beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.144] +synonym: "beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.144] +synonym: "GnTIII activity" EXACT [EC:2.4.1.144] +synonym: "N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] +synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.144] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III" RELATED [EC:2.4.1.144] +xref: EC:2.4.1.144 +xref: MetaCyc:2.4.1.144-RXN +xref: Reactome:R-HSA-975926 "Addition of a bifurcating GlcNAc to the N-glycan by MGAT3" +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0003831 +name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide." [EC:2.4.1.38] +synonym: "beta-N-acetyl-beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "beta-N-acetyl-beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "GalT activity" RELATED [EC:2.4.1.38] +synonym: "glycoprotein 4-beta-galactosyl-transferase activity" EXACT [EC:2.4.1.38] +synonym: "glycoprotein 4-beta-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "glycoprotein beta-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "thyroid galactosyltransferase activity" NARROW [EC:2.4.1.38] +synonym: "thyroid glycoprotein beta-galactosyltransferase" NARROW [EC:2.4.1.38] +synonym: "UDP-galactose--glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "UDPgalactose-glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] +synonym: "uridine diphosphogalactose-glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] +xref: EC:2.4.1.38 +xref: MetaCyc:2.4.1.38-RXN +xref: Reactome:R-HSA-1912352 "Galactosylation of Pre-NOTCH" +xref: Reactome:R-HSA-2025723 "B4GALTs transfer Gal to the N-glycan precursor" +xref: Reactome:R-HSA-2046265 "B4GALTs transfer Gal to the keratan chain" +xref: Reactome:R-HSA-2046298 "B4GALTs transfer Gal to a branch of keratan" +xref: Reactome:R-HSA-3656230 "Defective B4GALT1 does not transfer Gal to the keratan chain" +xref: Reactome:R-HSA-4793956 "Defective B4GALT1 does not add Gal to N-glycan" +xref: Reactome:R-HSA-9035949 "Defective B4GALT1 does not transfer Gal to the N-glycan precursor" +xref: Reactome:R-HSA-9035950 "Defective B4GALT1 does not transfer Gal to a branch of keratan" +xref: Reactome:R-HSA-975919 "Addition of galactose by beta 4-galactosyltransferases" +xref: RHEA:22932 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0003832 +name: beta-alanyl-dopamine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine." [GOC:bf, ISBN:0198506732, PMID:12957543] +synonym: "N-beta-alanyl-dopamine hydrolase activity" EXACT [] +synonym: "NBAD hydrolase activity" EXACT [] +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0003833 +name: beta-alanyl-dopamine synthase activity +namespace: molecular_function +def: "Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine)." [GOC:bf, ISBN:0198506732, PMID:12957543] +synonym: "N-beta-alanyl dopamine synthetase activity" EXACT [] +synonym: "NBAD transferase activity" EXACT [] +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0003834 +name: beta-carotene 15,15'-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + O(2) = 2 retinal." [EC:1.14.99.36, RHEA:32887] +comment: Note that this function was formerly EC:1.13.11.21. +synonym: "beta-carotene 15,15'-dioxygenase activity" EXACT [] +synonym: "beta-carotene:oxygen 15,15'-oxidoreductase (bond-cleaving)" EXACT [EC:1.14.99.36] +synonym: "carotene 15,15'-dioxygenase activity" EXACT [EC:1.14.99.36] +synonym: "carotene dioxygenase activity" EXACT [EC:1.14.99.36] +xref: EC:1.14.99.36 +xref: KEGG_REACTION:R00032 +xref: MetaCyc:BETA-CAROTENE-1515-DIOXYGENASE-RXN +xref: Reactome:R-HSA-975635 "BCMO1:Fe2+ cleaves betaC to atRAL" +xref: RHEA:32887 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0003835 +name: beta-galactoside alpha-2,6-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine." [EC:2.4.99.1] +synonym: "beta-galactosamide alpha-2,6-sialyltransferase activity" EXACT [] +synonym: "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.1] +synonym: "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.1] +xref: EC:2.4.99.1 +xref: MetaCyc:2.4.99.1-RXN +xref: Reactome:R-HSA-4085033 "ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)" +xref: Reactome:R-HSA-975902 "ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans" +xref: Reactome:R-HSA-977071 "Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position" +xref: Reactome:R-HSA-977228 "Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position" +xref: RHEA:11836 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0003836 +name: beta-galactoside (CMP) alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R." [EC:2.4.99.4] +synonym: "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity" EXACT [EC:2.4.99.4] +synonym: "CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity" EXACT [EC:2.4.99.4] +xref: EC:2.4.99.4 +xref: MetaCyc:2.4.99.4-RXN +xref: Reactome:R-HSA-1022129 "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans" +xref: Reactome:R-HSA-1912378 "Sialylation of Pre-NOTCH" +xref: Reactome:R-HSA-2046285 "The keratan chain can be capped by N-acetylneuraminic acid" +xref: Reactome:R-HSA-3656258 "Defective ST3GAL3 does not transfer SA to keratan" +xref: Reactome:R-HSA-4084984 "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)" +xref: Reactome:R-HSA-9603987 "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG" +xref: Reactome:R-HSA-9605600 "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG" +xref: Reactome:R-HSA-981497 "ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position" +xref: RHEA:21616 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0003837 +name: beta-ureidopropionase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3." [EC:3.5.1.6] +synonym: "N-carbamoyl-beta-alanine amidohydrolase activity" EXACT [EC:3.5.1.6] +xref: EC:3.5.1.6 +xref: MetaCyc:BETA-UREIDOPROPIONASE-RXN +xref: Reactome:R-HSA-73591 "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2" +xref: Reactome:R-HSA-73620 "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2" +xref: RHEA:11184 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0003838 +name: sterol 24-C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol." [EC:2.1.1.41] +synonym: "24-sterol C-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "delta(24)-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "delta(24)-sterol C-methyltransferase activity" EXACT [] +synonym: "delta(24)-sterol methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "delta24-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "delta24-sterol methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "phytosterol methyltransferase activity" NARROW [EC:2.1.1.41] +synonym: "S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "S-adenosyl-4-methionine:sterol delta24-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity" EXACT [EC:2.1.1.41] +synonym: "SMT1 activity" NARROW [EC:2.1.1.41] +synonym: "zymosterol-24-methyltransferase activity" NARROW [EC:2.1.1.41] +xref: EC:2.1.1.41 +xref: MetaCyc:RXN3O-178 +xref: RHEA:21128 +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0003839 +name: gamma-glutamylcyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid." [PMID:18515354] +synonym: "(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)" EXACT [] +synonym: "gamma-glutamyl-amino acid cyclotransferase activity" EXACT [] +synonym: "gamma-L-glutamylcyclotransferase activity" EXACT [] +synonym: "L-glutamic cyclase activity" EXACT [] +xref: EC:4.3.2.9 +xref: MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN +xref: Reactome:R-HSA-1247922 "GGCT transforms gGluCys to OPRO" +xref: Reactome:R-HSA-6785928 "CHAC1,2 cleaves GSH to OPRO and CysGly" +is_a: GO:0016842 ! amidine-lyase activity + +[Term] +id: GO:0003840 +name: obsolete gamma-glutamyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid." [EC:2.3.2.2] +comment: This term was obsoleted because it does not correspond to a physiological reaction.\nUsage comment: The gene family commonly referred to as gamma-glutamyl transferases (GGT) catalyze hydrolysis of gamma-glutamyl bonds in gamma-glutamyl compounds such as glutathione. In a test tube one can set up conditions in which the enzyme will transfer the gamma-glutamyl portion of the substrate to an acceptor molecule, but this requires non-physiologic conditions, including millmolar concentrations of an acceptor such as glygly. This reaction is used in assays to detect the presence of the enzyme, but is not a physiological function of members of the GGT family (PMC4388159), which should be annotated to a suitable hydrolysis term instead (e.g. glutathione hydrolase activity). +synonym: "(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity" EXACT [EC:2.3.2.2] +synonym: "alpha-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] +synonym: "gamma-glutamyl peptidyltransferase activity" EXACT [EC:2.3.2.2] +synonym: "gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] +synonym: "gamma-GPT" RELATED [EC:2.3.2.2] +synonym: "gamma-GT" RELATED [EC:2.3.2.2] +synonym: "gamma-GTP" RELATED [EC:2.3.2.2] +synonym: "glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] +synonym: "L-gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] +synonym: "L-gamma-glutamyltransferase activity" EXACT [EC:2.3.2.2] +synonym: "L-glutamyltransferase activity" EXACT [EC:2.3.2.2] +xref: EC:2.3.2.2 +xref: KEGG_REACTION:R04159 +xref: MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN +is_obsolete: true +consider: GO:0036374 + +[Term] +id: GO:0003841 +name: 1-acylglycerol-3-phosphate O-acyltransferase activity +namespace: molecular_function +alt_id: GO:0004469 +def: "Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate." [EC:2.3.1.51, GOC:ab] +synonym: "1-acyl-sn-glycero-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "1-acyl-sn-glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "1-acyl-sn-glycerol-3-phosphate acyltransferase activity" EXACT [] +synonym: "1-acylglycero-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "1-acylglycerolphosphate acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "1-acylglycerophosphate acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity" EXACT [EC:2.3.1.51] +synonym: "lysophosphatidate acyltransferase activity" EXACT [] +synonym: "lysophosphatidic acid-acyltransferase activity" RELATED [EC:2.3.1.51] +xref: EC:2.3.1.51 +xref: MetaCyc:RXN-1623 +xref: Reactome:R-HSA-1482539 "1-acyl LPG is acylated to PG by LPGAT" +xref: Reactome:R-HSA-1482547 "1-acyl LPC is acylated to PC by LPCAT" +xref: Reactome:R-HSA-1482548 "1-acyl LPA is acylated to PA by AGPAT5 (OM)" +xref: Reactome:R-HSA-1482598 "1-acyl LPI is acylated to PI by MBOAT7" +xref: Reactome:R-HSA-1482636 "1-acyl LPS is acylated to PS by LPSAT" +xref: Reactome:R-HSA-1482667 "1-acyl LPE is acylated to PE by LPEAT" +xref: Reactome:R-HSA-1482689 "1-acyl LPG is acylated to PG by CRLS1 (IM)" +xref: Reactome:R-HSA-1482894 "CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)" +xref: Reactome:R-HSA-75885 "1-acyl LPA is acylated to PA by AGPAT (LPAAT)" +xref: Reactome:R-HSA-8849345 "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine" +xref: RHEA:19709 +is_a: GO:0016411 ! acylglycerol O-acyltransferase activity +is_a: GO:0042171 ! lysophosphatidic acid acyltransferase activity + +[Term] +id: GO:0003842 +name: 1-pyrroline-5-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+)." [EC:1.2.1.88] +synonym: "1-pyrroline dehydrogenase" BROAD [] +synonym: "1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.12] +synonym: "delta1-pyrroline-5-carboxylate dehydrogenase activity" EXACT [EC:1.2.1.88] +synonym: "L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity" RELATED [] +synonym: "pyrroline-5-carboxylate dehydrogenase activity" EXACT [EC:1.2.1.88] +synonym: "pyrroline-5-carboxylic acid dehydrogenase activity" EXACT [EC:1.2.1.88] +xref: EC:1.2.1.88 +xref: MetaCyc:PYRROLINECARBDEHYDROG-RXN +xref: Reactome:R-HSA-6784399 "ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate" +xref: Reactome:R-HSA-70679 "ALDH4A1 oxidises L-GluSS to Glu" +xref: RHEA:16417 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003843 +name: 1,3-beta-D-glucan synthase activity +namespace: molecular_function +alt_id: GO:0009981 +def: "Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1)." [EC:2.4.1.34] +synonym: "(1,3)-beta-glucan (callose) synthase activity" EXACT [EC:2.4.1.34] +synonym: "1,3-beta-D-glucan synthetase activity" EXACT [EC:2.4.1.34] +synonym: "1,3-beta-D-glucan-UDP glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "1,3-beta-glucan synthase activity" EXACT [EC:2.4.1.34] +synonym: "1,3-beta-glucan-uridine diphosphoglucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "beta-1,3-glucan synthase activity" EXACT [] +synonym: "beta-1,3-glucan synthetase activity" EXACT [EC:2.4.1.34] +synonym: "callose synthase activity" EXACT [] +synonym: "callose synthetase activity" EXACT [EC:2.4.1.34] +synonym: "GS-II" RELATED [EC:2.4.1.34] +synonym: "paramylon synthetase" RELATED [EC:2.4.1.34] +synonym: "UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "UDP-glucose-1,3-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "UDP-glucose-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "UDP-glucose:(1,3)beta-glucan synthase activity" EXACT [EC:2.4.1.34] +synonym: "UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "UDPglucose-1,3-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.34] +synonym: "uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] +xref: EC:2.4.1.34 +xref: MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0003844 +name: 1,4-alpha-glucan branching enzyme activity +namespace: molecular_function +def: "Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain." [EC:2.4.1.18] +synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity" EXACT [] +synonym: "1,4-glucan-6-(1,4-glucano)-transferase activity" EXACT [] +synonym: "alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity" EXACT [EC:2.4.1.18] +synonym: "alpha-glucan-branching glycosyltransferase activity" EXACT [EC:2.4.1.18] +synonym: "amylo-(1,4 to 1,6)transglucosidase activity" EXACT [EC:2.4.1.18] +synonym: "amylo-(1,4->1,6)-transglycosylase activity" EXACT [EC:2.4.1.18] +synonym: "amylose isomerase activity" EXACT [EC:2.4.1.18] +synonym: "branching enzyme activity" RELATED [EC:2.4.1.18] +synonym: "branching glycosyltransferase activity" EXACT [EC:2.4.1.18] +synonym: "enzymatic branching factor" RELATED [EC:2.4.1.18] +synonym: "enzyme Q" RELATED [EC:2.4.1.18] +synonym: "glucosan transglycosylase activity" EXACT [EC:2.4.1.18] +synonym: "glycogen branching enzyme activity" EXACT [EC:2.4.1.18] +synonym: "plant branching enzyme" RELATED [EC:2.4.1.18] +synonym: "Q-enzyme" RELATED [EC:2.4.1.18] +synonym: "starch branching enzyme" RELATED [EC:2.4.1.18] +xref: EC:2.4.1.18 +xref: MetaCyc:GLYCOGEN-BRANCH-RXN +xref: Reactome:R-HSA-3322005 "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a" +xref: Reactome:R-HSA-3322016 "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a" +xref: Reactome:R-HSA-3322057 "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b" +xref: Reactome:R-HSA-3878762 "Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver)" +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0003845 +name: 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity +namespace: molecular_function +def: "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+)." [EC:1.1.1.146, PMID:15761036] +synonym: "11beta-hydroxy steroid dehydrogenase" EXACT [EC:1.1.1.146] +synonym: "11beta-hydroxysteroid dehydrogenase" EXACT [EC:1.1.1.146] +synonym: "beta-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.146] +synonym: "corticosteroid 11-reductase" RELATED [EC:1.1.1.146] +synonym: "corticosteroid 11beta-dehydrogenase" RELATED [EC:1.1.1.146] +synonym: "dehydrogenase, 11beta-hydroxy steroid" EXACT [EC:1.1.1.146] +xref: MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-194023 "HSD11B2,HSD11B1 dimer oxidise CORT to COR" +xref: Wikipedia:11beta-hydroxysteroid_dehydrogenase +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003846 +name: 2-acylglycerol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol." [EC:2.3.1.22] +synonym: "acyl coenzyme A-monoglyceride acyltransferase activity" EXACT [EC:2.3.1.22] +synonym: "acyl-CoA:2-acylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.22] +synonym: "acylglycerol palmitoyltransferase activity" EXACT [EC:2.3.1.22] +synonym: "monoacylglycerol acyltransferase activity" EXACT [EC:2.3.1.22] +synonym: "monoglyceride acyltransferase activity" EXACT [EC:2.3.1.22] +xref: EC:2.3.1.22 +xref: MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-5696448 "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG" +xref: Reactome:R-HSA-6800334 "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG" +xref: RHEA:16741 +is_a: GO:0016411 ! acylglycerol O-acyltransferase activity + +[Term] +id: GO:0003847 +name: 1-alkyl-2-acetylglycerophosphocholine esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate." [EC:3.1.1.47] +subset: goslim_chembl +synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity" EXACT [EC:3.1.1.47] +synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity" EXACT [EC:3.1.1.47] +synonym: "2-acetyl-1-alkylglycerophosphocholine esterase activity" EXACT [] +synonym: "alkylacetyl-GPC:acetylhydrolase activity" EXACT [EC:3.1.1.47] +synonym: "LDL-associated phospholipase A(2) activity" RELATED [EC:3.1.1.47] +synonym: "LDL-associated phospholipase A2" RELATED [EC:3.1.1.47] +synonym: "LDL-PLA(2) activity" RELATED [EC:3.1.1.47] +synonym: "LDL-PLA2" RELATED [EC:3.1.1.47] +synonym: "PAF 2-acylhydrolase activity" RELATED [EC:3.1.1.47] +synonym: "PAF acetylhydrolase activity" RELATED [EC:3.1.1.47] +synonym: "platelet-activating factor acetylhydrolase activity" RELATED [EC:3.1.1.47] +xref: EC:3.1.1.47 +xref: MetaCyc:3.1.1.47-RXN +xref: Reactome:R-HSA-8869206 "PAFAH2 hydrolyses PAF to lyso-PAF and acetate" +xref: RHEA:17777 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0003848 +name: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+)." [EC:2.7.6.3, RHEA:11412] +subset: goslim_chembl +synonym: "2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity" EXACT [] +synonym: "6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "7,8-dihydroxymethylpterin-pyrophosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity" EXACT [EC:2.7.6.3] +synonym: "H2-pteridine-CH2OH pyrophosphokinase activity" EXACT [EC:2.7.6.3] +synonym: "HPPK" RELATED [EC:2.7.6.3] +synonym: "hydroxymethyldihydropteridine pyrophosphokinase activity" EXACT [EC:2.7.6.3] +xref: EC:2.7.6.3 +xref: KEGG_REACTION:R03503 +xref: MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN +xref: RHEA:11412 +is_a: GO:0016778 ! diphosphotransferase activity + +[Term] +id: GO:0003849 +name: 3-deoxy-7-phosphoheptulonate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate." [EC:2.5.1.54, RHEA:14717] +comment: Note that this function was formerly EC:4.1.2.15. +synonym: "2-dehydro-3-deoxy-phosphoheptonate aldolase activity" EXACT [EC:2.5.1.54] +synonym: "2-dehydro-3-deoxyphosphoheptonate aldolase activity" EXACT [] +synonym: "2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] +synonym: "3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] +synonym: "3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity" EXACT [EC:2.5.1.54] +synonym: "3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] +synonym: "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate" RELATED [EC:2.5.1.54] +synonym: "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] +synonym: "7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] +synonym: "D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] +synonym: "D-erythrose-4-phosphate-lyase activity" RELATED [EC:2.5.1.54] +synonym: "DAH7-P synthase activity" EXACT [EC:2.5.1.54] +synonym: "DAHP synthase activity" EXACT [EC:2.5.1.54] +synonym: "deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity" EXACT [EC:2.5.1.54] +synonym: "DHAP synthase activity" EXACT [EC:2.5.1.54] +synonym: "DS-Co activity" RELATED [EC:2.5.1.54] +synonym: "DS-Mn activity" RELATED [EC:2.5.1.54] +synonym: "KDPH synthase activity" EXACT [EC:2.5.1.54] +synonym: "KDPH synthetase activity" EXACT [EC:2.5.1.54] +synonym: "phospho-2-dehydro-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] +synonym: "phospho-2-keto-3-deoxyheptanoate aldolase activity" EXACT [EC:2.5.1.54] +synonym: "phospho-2-keto-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] +synonym: "phospho-2-keto-3-deoxyheptonic aldolase activity" EXACT [EC:2.5.1.54] +synonym: "phospho-2-oxo-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] +synonym: "phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.54] +xref: EC:2.5.1.54 +xref: KEGG_REACTION:R01826 +xref: MetaCyc:DAHPSYN-RXN +xref: RHEA:14717 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0003850 +name: 2-deoxyglucose-6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate." [EC:3.1.3.68] +synonym: "2-deoxy-D-glucose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.68] +synonym: "2-deoxyglucose-6-phosphate phosphatase activity" EXACT [EC:3.1.3.68] +xref: EC:3.1.3.68 +xref: KEGG_REACTION:R02587 +xref: MetaCyc:3.1.3.68-RXN +xref: RHEA:22236 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0003851 +name: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine." [EC:2.4.1.45] +synonym: "cerebroside synthase activity" EXACT [EC:2.4.1.45] +synonym: "UDP-galactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.45] +synonym: "UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity" EXACT [EC:2.4.1.45] +synonym: "UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] +synonym: "UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity" EXACT [EC:2.4.1.45] +synonym: "UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] +synonym: "UDPgalactose:ceramide galactosyltransferase activity" EXACT [EC:2.4.1.45] +synonym: "uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] +xref: EC:2.4.1.47 +xref: MetaCyc:2.4.1.45-RXN +xref: RHEA:10856 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0003852 +name: 2-isopropylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+)." [EC:2.3.3.13, RHEA:21524] +comment: Note that this function was formerly EC:4.1.3.12. +synonym: "3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.13] +synonym: "acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.13] +synonym: "alpha-IPM synthetase activity" EXACT [EC:2.3.3.13] +synonym: "alpha-isopropylmalate synthase activity" EXACT [EC:2.3.3.13] +synonym: "alpha-isopropylmalate synthetase activity" EXACT [EC:2.3.3.13] +synonym: "alpha-isopropylmalic synthetase activity" EXACT [EC:2.3.3.13] +synonym: "isopropylmalate synthase activity" EXACT [EC:2.3.3.13] +synonym: "isopropylmalate synthetase activity" EXACT [EC:2.3.3.13] +xref: EC:2.3.3.13 +xref: KEGG_REACTION:R01213 +xref: MetaCyc:2-ISOPROPYLMALATESYN-RXN +xref: RHEA:21524 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0003853 +name: 2-methylacyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor." [EC:1.3.99.12] +synonym: "2-methyl branched chain acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.12] +synonym: "2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.12] +synonym: "2-methylbutanoyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.99.12] +synonym: "branched-chain acyl-CoA dehydrogenase activity" RELATED [EC:1.3.99.12] +xref: EC:1.3.99.12 +xref: MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN +xref: RHEA:13261 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0003854 +name: 3-beta-hydroxy-delta5-steroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+)." [EC:1.1.1.145] +synonym: "3-beta-hydroxy-5-ene steroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "3-beta-hydroxy-D5-steroid dehydrogenase activity" EXACT [] +synonym: "3beta-HSDH" RELATED [EC:1.1.1.145] +synonym: "3beta-hydroxy steroid dehydrogenase/isomerase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-5-ene steroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-5-ene-steroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-5-ene-steroid oxidoreductase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-delta5-C27-steroid oxidoreductase" BROAD [EC:1.1.1.145] +synonym: "3beta-hydroxy-delta5-steroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.145] +synonym: "5-ene-3-beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "delta5-3beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.145] +synonym: "progesterone reductase activity" BROAD [EC:1.1.1.145] +synonym: "steroid-delta5-3beta-ol dehydrogenase activity" EXACT [EC:1.1.1.145] +xref: EC:1.1.1.145 +xref: MetaCyc:1.1.1.145-RXN +xref: Reactome:R-HSA-192097 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one" +xref: Reactome:R-HSA-193789 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one" +xref: Reactome:R-HSA-193816 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one" +xref: Reactome:R-HSA-196350 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione" +xref: Reactome:R-HSA-196372 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol" +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003855 +name: 3-dehydroquinate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O." [EC:4.2.1.10, RHEA:21096] +synonym: "3-dehydroquinase activity" EXACT [EC:4.2.1.10] +synonym: "3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)" EXACT [EC:4.2.1.10] +synonym: "3-dehydroquinate hydro-lyase activity" EXACT [EC:4.2.1.10] +synonym: "3-dehydroquinate hydrolase activity" EXACT [EC:4.2.1.10] +synonym: "5-dehydroquinase activity" EXACT [EC:4.2.1.10] +synonym: "5-dehydroquinate dehydratase activity" EXACT [EC:4.2.1.10] +synonym: "5-dehydroquinate hydro-lyase activity" EXACT [EC:4.2.1.10] +synonym: "dehydroquinase activity" EXACT [EC:4.2.1.10] +synonym: "dehydroquinate dehydratase activity" EXACT [EC:4.2.1.10] +synonym: "DHQase" EXACT [EC:4.2.1.10] +xref: EC:4.2.1.10 +xref: KEGG_REACTION:R03084 +xref: MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN +xref: RHEA:21096 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0003856 +name: 3-dehydroquinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate." [EC:4.2.3.4, RHEA:21968] +xref: EC:4.2.3.4 +xref: KEGG_REACTION:R03083 +xref: MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN +xref: RHEA:21968 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0003857 +name: 3-hydroxyacyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+)." [EC:1.1.1.35] +comment: See also 'long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509'. +synonym: "3-oxoacyl-thioester reductase activity" RELATED [PMID:19685079] +synonym: "beta-hydroxyacyl dehydrogenase activity" EXACT [EC:1.1.1.35] +synonym: "beta-hydroxyacyl-coenzyme A synthetase activity" EXACT [EC:1.1.1.35] +synonym: "beta-hydroxyacylcoenzyme A dehydrogenase activity" EXACT [EC:1.1.1.35] +synonym: "beta-hydroxybutyrylcoenzyme A dehydrogenase activity" NARROW [EC:1.1.1.35] +synonym: "beta-keto-reductase activity" EXACT [EC:1.1.1.35] +synonym: "beta-ketoacyl-CoA reductase" BROAD [EC:1.1.1.35] +synonym: "L-3-hydroxyacyl CoA dehydrogenase activity" EXACT [EC:1.1.1.35] +synonym: "L-3-hydroxyacyl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.35] +xref: EC:1.1.1.35 +xref: MetaCyc:OHACYL-COA-DEHYDROG-RXN +xref: Reactome:R-HSA-193455 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA" +xref: Reactome:R-HSA-193508 "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA" +xref: Reactome:R-HSA-389995 "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+" +xref: Reactome:R-HSA-390251 "HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA" +xref: Reactome:R-HSA-508369 "alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+" +xref: Reactome:R-HSA-6809264 "EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA" +xref: Reactome:R-HSA-70837 "alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+" +xref: Reactome:R-HSA-77254 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H" +xref: Reactome:R-HSA-77283 "(S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H" +xref: Reactome:R-HSA-77303 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H" +xref: Reactome:R-HSA-77312 "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H" +xref: Reactome:R-HSA-77323 "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H" +xref: Reactome:R-HSA-77331 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H" +xref: Reactome:R-HSA-77342 "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H" +xref: RHEA:22432 +xref: UM-BBD_enzymeID:e0664 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003858 +name: 3-hydroxybutyrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH." [EC:1.1.1.30, RHEA:20521] +synonym: "D-beta-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.30] +xref: EC:1.1.1.30 +xref: KEGG_REACTION:R01361 +xref: MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-5696457 "BDH2 dehydrogenates 3HBA" +xref: Reactome:R-HSA-73912 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+" +xref: Reactome:R-HSA-73920 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+" +xref: RHEA:20521 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003859 +name: 3-hydroxybutyryl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O." [EC:4.2.1.55, RHEA:17849] +synonym: "(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)" EXACT [EC:4.2.1.55] +synonym: "(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.55] +synonym: "crotonase activity" EXACT [EC:4.2.1.55] +synonym: "D-3-hydroxybutyryl coenzyme A dehydratase activity" EXACT [EC:4.2.1.55] +synonym: "D-3-hydroxybutyryl-CoA dehydratase activity" EXACT [EC:4.2.1.55] +synonym: "enoyl coenzyme A hydrase (D)" BROAD [EC:4.2.1.55] +xref: EC:4.2.1.55 +xref: KEGG_REACTION:R03027 +xref: MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN +xref: RHEA:17849 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0003860 +name: 3-hydroxyisobutyryl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate." [EC:3.1.2.4] +synonym: "3-hydroxy-2-methylpropanoyl-CoA hydrolase activity" EXACT [EC:3.1.2.4] +synonym: "3-hydroxy-isobutyryl CoA hydrolase activity" EXACT [EC:3.1.2.4] +synonym: "HIB CoA deacylase activity" EXACT [EC:3.1.2.4] +xref: EC:3.1.2.4 +xref: MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN +xref: Reactome:R-HSA-70881 "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA" +xref: RHEA:20888 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0003861 +name: 3-isopropylmalate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate." [EC:4.2.1.33] +synonym: "(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)" EXACT [EC:4.2.1.33] +synonym: "(2R,3S)-3-isopropylmalate hydro-lyase activity" EXACT [EC:4.2.1.33] +synonym: "alpha-IPM isomerase activity" EXACT [EC:4.2.1.33] +synonym: "alpha-isopropylmalate isomerase activity" EXACT [EC:4.2.1.33] +synonym: "beta-isopropylmalate dehydratase activity" EXACT [EC:4.2.1.33] +synonym: "isopropylmalate isomerase activity" EXACT [EC:4.2.1.33] +xref: EC:4.2.1.33 +xref: MetaCyc:3-ISOPROPYLMALISOM-RXN +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0003862 +name: 3-isopropylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+." [EC:1.1.1.85, RHEA:32271] +synonym: "(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.85] +synonym: "3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.85] +synonym: "beta-IPM dehydrogenase activity" EXACT [EC:1.1.1.85] +synonym: "beta-isopropylmalate dehydrogenase activity" EXACT [EC:1.1.1.85] +synonym: "beta-isopropylmalic enzyme" RELATED [EC:1.1.1.85] +synonym: "IMDH activity" EXACT [EC:1.1.1.85] +synonym: "IPMDH" RELATED [EC:1.1.1.85] +synonym: "threo-Ds-3-isopropylmalate dehydrogenase activity" EXACT [EC:1.1.1.85] +xref: EC:1.1.1.85 +xref: MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN +xref: RHEA:32271 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003863 +name: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2." [EC:1.2.4.4] +synonym: "2-oxoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "2-oxoisovalerate (lipoate) dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity" EXACT [EC:1.2.4.4] +synonym: "3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)" EXACT [EC:1.2.4.4] +synonym: "3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity" EXACT [EC:1.2.4.4] +synonym: "alpha-keto-alpha-methylvalerate dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "alpha-ketoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "alpha-ketoisocaproic dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "alpha-ketoisovalerate dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "alpha-oxoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] +synonym: "BCKDH activity" RELATED [EC:1.2.4.4] +synonym: "BCOAD activity" RELATED [EC:1.2.4.4] +synonym: "branched chain keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain (-2-oxoacid) dehydrogenase (BCD) activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain 2-keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain 2-oxo acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain alpha-keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain alpha-oxo acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "branched-chain ketoacid dehydrogenase activity" RELATED [EC:1.2.4.4] +synonym: "dehydrogenase, 2-oxoisovalerate (lipoate) activity" EXACT [EC:1.2.4.4] +synonym: "dehydrogenase, branched chain alpha-keto acid activity" RELATED [EC:1.2.4.4] +xref: EC:1.2.4.4 +xref: MetaCyc:1.2.4.4-RXN +is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor + +[Term] +id: GO:0003864 +name: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate." [EC:2.1.2.11] +synonym: "5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +synonym: "5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +synonym: "alpha-ketoisovalerate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +synonym: "dehydropantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +synonym: "ketopantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +synonym: "oxopantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] +xref: EC:2.1.2.11 +xref: MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN +xref: RHEA:11824 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0003865 +name: 3-oxo-5-alpha-steroid 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor." [EC:1.3.99.5] +synonym: "3-keto-delta4-steroid-5alpha-reductase activity" EXACT [EC:1.3.99.5] +synonym: "3-oxo-5alpha-steroid 4-dehydrogenase activity" EXACT [EC:1.3.99.5] +synonym: "3-oxo-5alpha-steroid delta4-dehydrogenase activity" EXACT [EC:1.3.99.5] +synonym: "3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity" EXACT [EC:1.3.99.5] +synonym: "3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity" EXACT [EC:1.3.99.5] +synonym: "3-oxosteroid delta4-dehydrogenase" BROAD [EC:1.3.99.5] +synonym: "4-ene-3-ketosteroid-5alpha-oxidoreductase activity" EXACT [EC:1.3.99.5] +synonym: "5alpha-reductase" BROAD [EC:1.3.99.5] +synonym: "delta4-3-keto steroid 5alpha-reductase activity" EXACT [EC:1.3.99.5] +synonym: "delta4-3-ketosteroid5alpha-oxidoreductase activity" EXACT [EC:1.3.99.5] +synonym: "delta4-3-oxo steroid reductase activity" EXACT [EC:1.3.99.5] +synonym: "delta4-3-oxosteroid-5alpha-reductase" BROAD [EC:1.3.99.5] +synonym: "delta4-5alpha-dehydrogenase activity" EXACT [EC:1.3.99.5] +synonym: "steroid 5 alpha reductase" BROAD [EC:1.3.99.5] +synonym: "steroid 5-alpha-reductase activity" BROAD [EC:1.3.99.5] +synonym: "steroid 5alpha-reductase" BROAD [EC:1.3.99.5] +synonym: "steroid delta4-5alpha-reductase activity" EXACT [EC:1.3.99.5] +synonym: "testosterone 5alpha-reductase" BROAD [EC:1.3.99.5] +xref: EC:1.3.99.5 +xref: MetaCyc:1.3.99.5-RXN +xref: Reactome:R-HSA-469659 "Testosterone is converted to 5-alpha-dihydroxytestosterone" +is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0003866 +name: 3-phosphoshikimate 1-carboxyvinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate." [EC:2.5.1.19, RHEA:21256] +synonym: "3-enol-pyruvoylshikimate-5-phosphate synthase activity" EXACT [EC:2.5.1.19] +synonym: "5-enolpyruvylshikimate-3-phosphate synthase activity" EXACT [EC:2.5.1.19] +synonym: "EPSP synthase activity" EXACT [EC:2.5.1.19] +synonym: "phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity" EXACT [EC:2.5.1.19] +xref: EC:2.5.1.19 +xref: KEGG_REACTION:R03460 +xref: MetaCyc:2.5.1.19-RXN +xref: RHEA:21256 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0003867 +name: 4-aminobutyrate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid." [GOC:mah] +synonym: "4-aminobutanoate transaminase activity" EXACT [] +synonym: "4-aminobutyrate aminotransferase activity" EXACT [] +synonym: "4-aminobutyric acid aminotransferase activity" EXACT [] +synonym: "aminobutyrate aminotransferase activity" EXACT [] +synonym: "aminobutyrate transaminase activity" EXACT [] +synonym: "beta-alanine aminotransferase" RELATED [] +synonym: "GABA aminotransferase activity" EXACT [] +synonym: "GABA transaminase activity" EXACT [] +synonym: "GABA transferase activity" EXACT [] +synonym: "gamma-amino-N-butyrate transaminase activity" EXACT [] +synonym: "gamma-aminobutyrate aminotransaminase activity" EXACT [] +synonym: "gamma-aminobutyrate transaminase activity" EXACT [] +synonym: "gamma-aminobutyric acid aminotransferase activity" EXACT [] +synonym: "gamma-aminobutyric acid transaminase activity" EXACT [] +synonym: "gamma-aminobutyric transaminase activity" EXACT [] +synonym: "glutamate-succinic semialdehyde transaminase activity" EXACT [] +xref: MetaCyc:GABATRANSAM-RXN +xref: Reactome:R-HSA-916855 "Conversion of GABA to Succinate Semialdehyde" +xref: RHEA:23352 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0003868 +name: 4-hydroxyphenylpyruvate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2." [EC:1.13.11.27] +synonym: "4-hydroxyphenylpyruvate hydroxylase activity" EXACT [EC:1.13.11.27] +synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)" EXACT [EC:1.13.11.27] +synonym: "4-hydroxyphenylpyruvic acid dioxygenase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvate dioxygenase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvate hydroxylase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvate oxidase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvic acid hydroxylase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvic hydroxylase activity" EXACT [EC:1.13.11.27] +synonym: "p-hydroxyphenylpyruvic oxidase activity" EXACT [EC:1.13.11.27] +xref: EC:1.13.11.27 +xref: MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN +xref: Reactome:R-HSA-71163 "p-hydroxyphenylpyruvate + O2 => homogentisate + CO2" +xref: RHEA:16189 +xref: UM-BBD_reactionID:r0298 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0003870 +name: 5-aminolevulinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA." [EC:2.3.1.37, RHEA:12921] +synonym: "5-aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] +synonym: "5-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] +synonym: "5-aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] +synonym: "ALA synthase activity" EXACT [EC:2.3.1.37] +synonym: "ALA synthetase activity" EXACT [EC:2.3.1.37] +synonym: "ALAS activity" EXACT [EC:2.3.1.37] +synonym: "alpha-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] +synonym: "aminolevulinate synthase activity" EXACT [EC:2.3.1.37] +synonym: "aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] +synonym: "aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] +synonym: "aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] +synonym: "aminolevulinic synthetase activity" EXACT [EC:2.3.1.37] +synonym: "delta-ALA synthetase activity" EXACT [EC:2.3.1.37] +synonym: "delta-aminolevulinate synthase activity" EXACT [EC:2.3.1.37] +synonym: "delta-aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] +synonym: "delta-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] +synonym: "delta-aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] +synonym: "delta-aminolevulinic synthetase activity" EXACT [EC:2.3.1.37] +synonym: "succinyl-CoA:glycine C-succinyltransferase (decarboxylating)" EXACT [EC:2.3.1.37] +xref: EC:2.3.1.37 +xref: KEGG_REACTION:R00830 +xref: MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN +xref: Reactome:R-HSA-189442 "ALAS condenses SUCC-CoA and Gly to form dALA" +xref: RHEA:12921 +is_a: GO:0016749 ! N-succinyltransferase activity + +[Term] +id: GO:0003871 +name: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate." [EC:2.1.1.14, RHEA:21196] +synonym: "5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.14] +synonym: "cobalamin-independent methionine synthase activity" EXACT [EC:2.1.1.14] +synonym: "homocysteine methylase activity" EXACT [EC:2.1.1.14] +synonym: "MetE" RELATED [EC:2.1.1.14] +synonym: "methionine synthase (cobalamin-independent) activity" EXACT [EC:2.1.1.14] +synonym: "methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity" EXACT [EC:2.1.1.14] +synonym: "methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity" EXACT [EC:2.1.1.14] +synonym: "tetrahydropteroylglutamate-homocysteine transmethylase activity" EXACT [EC:2.1.1.14] +synonym: "tetrahydropteroyltriglutamate methyltransferase activity" EXACT [EC:2.1.1.14] +xref: EC:2.1.1.14 +xref: KEGG_REACTION:R04405 +xref: MetaCyc:HOMOCYSMET-RXN +xref: RHEA:21196 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0042085 ! 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity + +[Term] +id: GO:0003872 +name: 6-phosphofructokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate." [EC:2.7.1.11] +synonym: "6-phosphofructokinase reduction" EXACT [] +synonym: "6-phosphofructose 1-kinase activity" EXACT [EC:2.7.1.11] +synonym: "ATP-dependent phosphofructokinase activity" EXACT [EC:2.7.1.11] +synonym: "ATP:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.11] +synonym: "D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.11] +synonym: "fructose 6-phosphate kinase activity" EXACT [EC:2.7.1.11] +synonym: "fructose 6-phosphokinase activity" EXACT [EC:2.7.1.11] +synonym: "nucleotide triphosphate-dependent phosphofructokinase activity" EXACT [EC:2.7.1.11] +synonym: "PFK" RELATED [EC:2.7.1.11] +synonym: "phospho-1,6-fructokinase activity" EXACT [EC:2.7.1.11] +synonym: "phosphofructokinase (phosphorylating)" EXACT [EC:2.7.1.11] +synonym: "phosphofructokinase I activity" EXACT [EC:2.7.1.11] +synonym: "phosphohexokinase activity" BROAD [EC:2.7.1.11] +xref: EC:2.7.1.11 +xref: MetaCyc:6PFRUCTPHOS-RXN +xref: Reactome:R-HSA-70467 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP" +xref: RHEA:16109 +is_a: GO:0008443 ! phosphofructokinase activity +relationship: part_of GO:0061615 ! glycolytic process through fructose-6-phosphate + +[Term] +id: GO:0003873 +name: 6-phosphofructo-2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.105, RHEA:15653] +synonym: "6-phosphofructo-2-kinase (phosphorylating)" EXACT [EC:2.7.1.105] +synonym: "6-phosphofructose 2-kinase activity" EXACT [EC:2.7.1.105] +synonym: "ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.105] +synonym: "ATP:D-fructose-6-phosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.105] +synonym: "fructose 6-phosphate 2-kinase activity" EXACT [EC:2.7.1.105] +synonym: "phosphofructokinase 2 activity" EXACT [EC:2.7.1.105] +xref: EC:2.7.1.105 +xref: KEGG_REACTION:R02732 +xref: MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN +xref: Reactome:R-HSA-71802 "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP" +xref: RHEA:15653 +is_a: GO:0008443 ! phosphofructokinase activity + +[Term] +id: GO:0003874 +name: 6-pyruvoyltetrahydropterin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate." [EC:4.2.3.12, RHEA:22048] +synonym: "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity" EXACT [EC:4.2.3.12] +synonym: "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)" EXACT [EC:4.2.3.12] +synonym: "6-pyruvoyl tetrahydrobiopterin synthase activity" EXACT [EC:4.2.3.12] +synonym: "PTPS activity" EXACT [EC:4.2.3.12] +xref: EC:4.2.3.12 +xref: KEGG_REACTION:R04286 +xref: MetaCyc:4.2.3.12-RXN +xref: Reactome:R-HSA-1474184 "DHNTP is dephosphorylated by PTPS to PTHP" +xref: RHEA:22048 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0003875 +name: ADP-ribosylarginine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose." [EC:3.2.2.19] +synonym: "ADP-ribose-L-arginine cleavage enzyme activity" EXACT [EC:3.2.2.19] +synonym: "ADP-ribose-L-arginine cleaving enzyme activity" EXACT [EC:3.2.2.19] +synonym: "ADPribosylarginine hydrolase activity" EXACT [] +synonym: "N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] +synonym: "nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] +synonym: "omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] +synonym: "protein ADP-ribosylarginine hydrolase activity" EXACT [EC:3.2.2.19] +synonym: "protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] +xref: EC:3.2.2.19 +xref: MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN +xref: RHEA:20784 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0003876 +name: AMP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + H2O = IMP + NH3." [EC:3.5.4.6] +synonym: "5-adenylate deaminase activity" EXACT [EC:3.5.4.6] +synonym: "5-adenylic acid deaminase activity" EXACT [EC:3.5.4.6] +synonym: "5-AMP deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenosine 5-monophosphate deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenosine 5-phosphate aminohydrolase activity" EXACT [EC:3.5.4.6] +synonym: "adenosine monophosphate deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenyl deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenylate aminohydrolase activity" EXACT [EC:3.5.4.6] +synonym: "adenylate deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenylate deaminase reaction" EXACT [] +synonym: "adenylate desaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenylic acid deaminase activity" EXACT [EC:3.5.4.6] +synonym: "adenylic deaminase activity" EXACT [EC:3.5.4.6] +synonym: "AMP aminase activity" EXACT [EC:3.5.4.6] +synonym: "AMP aminohydrolase activity" EXACT [EC:3.5.4.6] +synonym: "myoadenylate deaminase activity" NARROW [EC:3.5.4.6] +xref: EC:3.5.4.6 +xref: MetaCyc:AMP-DEAMINASE-RXN +xref: Reactome:R-HSA-76590 "AMP + H2O => IMP + NH4+ (AMPD)" +xref: RHEA:14777 +is_a: GO:0047623 ! adenosine-phosphate deaminase activity + +[Term] +id: GO:0003877 +name: ATP adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate." [EC:2.7.7.53] +synonym: "adenine triphosphate adenylyltransferase activity" EXACT [EC:2.7.7.53] +synonym: "ADP:ATP adenylyltransferase activity" EXACT [] +synonym: "AP-4-A phosphorylase activity" EXACT [EC:2.7.7.53] +synonym: "bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity" EXACT [EC:2.7.7.53] +synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity" EXACT [EC:2.7.7.53] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming)" EXACT [EC:2.7.7.53] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity" EXACT [EC:2.7.7.53] +synonym: "diadenosinetetraphosphate alpha-beta-phosphorylase activity" EXACT [EC:2.7.7.53] +synonym: "diadenosinetetraphosphate alphabeta-phosphorylase activity" EXACT [EC:2.7.7.53] +synonym: "dinucleoside oligophosphate alphabeta-phosphorylase activity" EXACT [EC:2.7.7.53] +xref: EC:2.7.7.53 +xref: MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN +xref: RHEA:16577 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0003878 +name: ATP citrate synthase activity +namespace: molecular_function +alt_id: GO:0046913 +def: "Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA." [EC:2.3.3.8, RHEA:21160] +comment: Note that this function was formerly EC:4.1.3.8. +synonym: "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [EC:2.3.3.8] +synonym: "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [EC:2.3.3.8] +synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [EC:2.3.3.8] +synonym: "adenosine triphosphate citrate lyase activity" EXACT [EC:2.3.3.8] +synonym: "ATP citrate (pro-S)-lyase activity" EXACT [EC:2.3.3.8] +synonym: "ATP-citrate (pro-S)-lyase activity" EXACT [] +synonym: "ATP-citrate (pro-S-)-lyase activity" EXACT [EC:2.3.3.8] +synonym: "ATP-citric lyase activity" EXACT [EC:2.3.3.8] +synonym: "ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [EC:2.3.3.8] +synonym: "ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [EC:2.3.3.8] +synonym: "citrate cleavage enzyme activity" RELATED [EC:2.3.3.8] +synonym: "citrate-ATP lyase activity" EXACT [EC:2.3.3.8] +synonym: "citric cleavage enzyme activity" RELATED [EC:2.3.3.8] +xref: EC:2.3.3.8 +xref: KEGG_REACTION:R00352 +xref: MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN +xref: MetaCyc:PWY-5172 +xref: Reactome:R-HSA-75848 "ACLY tetramer transforms CIT to Ac-CoA" +xref: RHEA:21160 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0003879 +name: ATP phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.17] +synonym: "1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.17] +synonym: "adenosine triphosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyl ATP synthetase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyl-ATP diphosphorylase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyl-ATP pyrophosphorylase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyladenosine triphosphate pyrophosphorylase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyladenosine triphosphate synthetase activity" EXACT [EC:2.4.2.17] +synonym: "phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] +xref: EC:2.4.2.17 +xref: MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN +xref: RHEA:18473 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0003880 +name: protein C-terminal carboxyl O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein." [PMID:8428937] +synonym: "C-terminal protein carboxyl methyltransferase activity" EXACT [] +is_a: GO:0051998 ! protein carboxyl O-methyltransferase activity +relationship: part_of GO:0006481 ! C-terminal protein methylation + +[Term] +id: GO:0003881 +name: CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+)." [EC:2.7.8.11, RHEA:11580] +synonym: "CDP diglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-DG:inositol transferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-diacylglycerol--inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-diglyceride-inositol transferase activity" EXACT [EC:2.7.8.11] +synonym: "CDP-diglyceride:inositol transferase activity" EXACT [EC:2.7.8.11] +synonym: "CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "cytidine diphosphoglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] +synonym: "cytidine diphosphoglyceride-inositol transferase activity" EXACT [EC:2.7.8.11] +synonym: "phosphatidylinositol synthase activity" EXACT [] +xref: EC:2.7.8.11 +xref: KEGG_REACTION:R01802 +xref: MetaCyc:2.7.8.11-RXN +xref: Reactome:R-HSA-1482976 "CDP-DAG is converted to PI by CDIPT" +xref: RHEA:11580 +is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity + +[Term] +id: GO:0003882 +name: CDP-diacylglycerol-serine O-phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine." [EC:2.7.8.8] +synonym: "CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] +synonym: "phosphatidylserine synthase activity" EXACT [EC:2.7.8.8] +synonym: "phosphatidylserine synthetase activity" EXACT [EC:2.7.8.8] +synonym: "PS synthase activity" EXACT [EC:2.7.8.8] +synonym: "serine exchange enzyme" BROAD [] +xref: EC:2.7.8.8 +xref: MetaCyc:PHOSPHASERSYN-RXN +xref: RHEA:16913 +is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity + +[Term] +id: GO:0003883 +name: CTP synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP." [EC:6.3.4.2] +synonym: "CTP synthetase activity" EXACT [EC:6.3.4.2] +synonym: "cytidine 5'-triphosphate synthetase activity" EXACT [EC:6.3.4.2] +synonym: "cytidine triphosphate synthetase activity" EXACT [EC:6.3.4.2] +synonym: "uridine triphosphate aminase activity" EXACT [EC:6.3.4.2] +synonym: "UTP--ammonia ligase activity" EXACT [EC:6.3.4.2] +synonym: "UTP:ammonia ligase (ADP-forming)" EXACT [EC:6.3.4.2] +xref: EC:6.3.4.2 +xref: MetaCyc:CTPSYN-RXN +xref: Reactome:R-HSA-504054 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]" +xref: Reactome:R-HSA-73647 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]" +xref: RHEA:16597 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0003884 +name: D-amino-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide." [EC:1.4.3.3] +synonym: "D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.3] +synonym: "L-amino acid:O2 oxidoreductase activity" EXACT [EC:1.4.3.3] +synonym: "new yellow enzyme" RELATED [EC:1.4.3.3] +xref: EC:1.4.3.3 +xref: MetaCyc:D-AMINO-ACID-OXIDASE-RXN +xref: Reactome:R-HSA-389821 "glycine + O2 => glyoxylate + H2O2 + NH4+" +xref: RHEA:21816 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0003885 +name: D-arabinono-1,4-lactone oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+)." [EC:1.1.3.37, RHEA:23756] +synonym: "D-arabinono-1,4-lactone:oxygen oxidoreductase activity" EXACT [EC:1.1.3.37] +xref: EC:1.1.3.37 +xref: KEGG_REACTION:R02715 +xref: MetaCyc:1.1.3.37-RXN +xref: RHEA:23756 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0003886 +name: DNA (cytosine-5-)-methyltransferase activity +namespace: molecular_function +alt_id: GO:0008326 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine." [EC:2.1.1.37] +comment: Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37). +synonym: "cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.37] +synonym: "cytosine DNA methylase activity" BROAD [EC:2.1.1.37] +synonym: "cytosine DNA methyltransferase activity" BROAD [EC:2.1.1.37] +synonym: "cytosine-specific DNA methyltransferase activity" EXACT [EC:2.1.1.37] +synonym: "deoxyribonucleic (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] +synonym: "deoxyribonucleic acid (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] +synonym: "deoxyribonucleic methylase activity" BROAD [EC:2.1.1.37] +synonym: "DNA 5-cytosine methylase activity" EXACT [EC:2.1.1.37] +synonym: "DNA cytosine C(5) methylase activity" EXACT [EC:2.1.1.37] +synonym: "DNA cytosine C5 methylase activity" EXACT [EC:2.1.1.37] +synonym: "DNA cytosine methylase activity" BROAD [EC:2.1.1.37] +synonym: "DNA-cytosine 5-methylase activity" EXACT [EC:2.1.1.37] +synonym: "DNA-cytosine methyltransferase activity" BROAD [EC:2.1.1.37] +synonym: "methylphosphotriester-DNA methyltransferase activity" RELATED [EC:2.1.1.37] +synonym: "modification methylase activity" RELATED [EC:2.1.1.37] +synonym: "restriction-modification system activity" RELATED [EC:2.1.1.37] +synonym: "S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] +synonym: "site-specific DNA-methyltransferase (cytosine-specific) activity" NARROW [EC:2.1.1.37] +synonym: "type II DNA methylase activity" RELATED [EC:2.1.1.37] +xref: EC:2.1.1.37 +xref: MetaCyc:2.1.1.73-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0009008 ! DNA-methyltransferase activity +relationship: part_of GO:0090116 ! C-5 methylation of cytosine + +[Term] +id: GO:0003887 +name: DNA-directed DNA polymerase activity +namespace: molecular_function +alt_id: GO:0003888 +alt_id: GO:0003889 +alt_id: GO:0003890 +alt_id: GO:0003891 +alt_id: GO:0003893 +alt_id: GO:0003894 +alt_id: GO:0003895 +alt_id: GO:0008723 +alt_id: GO:0015999 +alt_id: GO:0016000 +alt_id: GO:0016448 +alt_id: GO:0016449 +alt_id: GO:0016450 +alt_id: GO:0016451 +alt_id: GO:0016452 +alt_id: GO:0019984 +def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group." [EC:2.7.7.7, GOC:vw, ISBN:0198547684] +synonym: "alpha DNA polymerase activity" NARROW [] +synonym: "beta DNA polymerase activity" NARROW [] +synonym: "delta DNA polymerase activity" NARROW [] +synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleic acid duplicase activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleic duplicase activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleic polymerase I" NARROW [EC:2.7.7.7] +synonym: "DNA duplicase activity" EXACT [EC:2.7.7.7] +synonym: "DNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.7] +synonym: "DNA polymerase alpha" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase beta" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase gamma" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase I" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase II" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase III" NARROW [EC:2.7.7.7] +synonym: "DNA polymerase V activity" NARROW [] +synonym: "DNA replicase activity" EXACT [EC:2.7.7.7] +synonym: "DNA-dependent DNA polymerase activity" EXACT [EC:2.7.7.7] +synonym: "duplicase" BROAD [EC:2.7.7.7] +synonym: "epsilon DNA polymerase activity" NARROW [] +synonym: "eta DNA polymerase activity" NARROW [] +synonym: "gamma DNA-directed DNA polymerase activity" NARROW [] +synonym: "iota DNA polymerase activity" NARROW [] +synonym: "kappa DNA polymerase activity" NARROW [] +synonym: "Klenow fragment" NARROW [EC:2.7.7.7] +synonym: "lambda DNA polymerase activity" NARROW [] +synonym: "mu DNA polymerase activity" NARROW [] +synonym: "nu DNA polymerase activity" NARROW [] +synonym: "sequenase" RELATED [EC:2.7.7.7] +synonym: "sigma DNA polymerase activity" NARROW [] +synonym: "Taq DNA polymerase" NARROW [EC:2.7.7.7] +synonym: "Taq Pol I" NARROW [EC:2.7.7.7] +synonym: "Tca DNA polymerase" NARROW [EC:2.7.7.7] +synonym: "theta DNA polymerase activity" NARROW [] +synonym: "zeta DNA polymerase activity" NARROW [] +xref: EC:2.7.7.7 +xref: MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN +xref: Reactome:R-HSA-110311 "POLZ extends translesion synthesis" +xref: Reactome:R-HSA-110317 "Insertion of correct bases opposite the lesion by POLH" +xref: Reactome:R-HSA-110319 "Elongation by POLH" +xref: Reactome:R-HSA-110368 "POLD,POLE-mediated DNA strand displacement synthesis" +xref: Reactome:R-HSA-111253 "POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site" +xref: Reactome:R-HSA-164505 "Synthesis of full-length duplex viral DNA with a discontinuous plus strand" +xref: Reactome:R-HSA-164513 "3' PPT-primed initiation of plus-strand DNA synthesis" +xref: Reactome:R-HSA-174427 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere" +xref: Reactome:R-HSA-174444 "Formation of C-strand Okazaki fragments" +xref: Reactome:R-HSA-5358579 "DNA polymerase delta polymerizes DNA across single stranded gap" +xref: Reactome:R-HSA-5649723 "POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution" +xref: Reactome:R-HSA-5649883 "POLB-mediated DNA strand displacement synthesis" +xref: Reactome:R-HSA-5653840 "POLD,POLE complete replication of damaged DNA after TLS" +xref: Reactome:R-HSA-5655892 "POLK incorporates dNMP opposite to damaged DNA base" +xref: Reactome:R-HSA-5655965 "POLK and POLZ cooperate in elongation of mispaired primer termini" +xref: Reactome:R-HSA-5656148 "POLI incorporates dNMP opposite to damaged DNA base" +xref: Reactome:R-HSA-5656158 "POLZ elongates POLI-incorporated dNMP" +xref: Reactome:R-HSA-5687360 "POLL or POLM extends aligned DNA DSB ends to fill gaps" +xref: Reactome:R-HSA-5687640 "POLQ extends annealed 3'-ssDNA overhangs in MMEJ" +xref: Reactome:R-HSA-5691001 "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER" +xref: Reactome:R-HSA-5693593 "D-loop extension by DNA polymerases" +xref: Reactome:R-HSA-6782208 "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER" +xref: Reactome:R-HSA-6786166 "Translesion synthesis across unhooked ICL by POLN" +xref: Reactome:R-HSA-68950 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin" +xref: Reactome:R-HSA-69116 "Formation of Okazaki fragments" +xref: Reactome:R-HSA-73932 "Resynthesis of excised residue by POLB" +is_a: GO:0034061 ! DNA polymerase activity + +[Term] +id: GO:0003892 +name: obsolete proliferating cell nuclear antigen +namespace: molecular_function +alt_id: GO:0005661 +def: "OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair." [ISBN:0123668387] +comment: This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "PCNA" EXACT [] +synonym: "proliferating cell nuclear antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003896 +name: DNA primase activity +namespace: molecular_function +alt_id: GO:0003897 +alt_id: GO:0003898 +def: "Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases." [GOC:mah, GOC:mcc, ISBN:0716720094, PMID:26184436] +xref: EC:2.7.7.101 +is_a: GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity +relationship: part_of GO:0006269 ! DNA replication, synthesis of RNA primer + +[Term] +id: GO:0003899 +name: DNA-directed 5'-3' RNA polymerase activity +namespace: molecular_function +alt_id: GO:0000129 +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [EC:2.7.7.6, GOC:pf] +synonym: "C ribonucleic acid formation factors" RELATED [EC:2.7.7.6] +synonym: "C RNA formation factors" RELATED [EC:2.7.7.6] +synonym: "deoxyribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [EC:2.7.7.6] +synonym: "DNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.6] +synonym: "DNA-dependent RNA nucleotidyltransferase activity" EXACT [EC:2.7.7.6] +synonym: "DNA-dependent RNA polymerase activity" EXACT [EC:2.7.7.6] +synonym: "DNA-directed RNA polymerase activity" BROAD [] +synonym: "DNA-directed RNA polymerase I activity" NARROW [] +synonym: "DNA-directed RNA polymerase II activity" NARROW [] +synonym: "DNA-directed RNA polymerase III activity" NARROW [] +synonym: "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.6] +synonym: "RNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.6] +synonym: "RNA polymerase I activity" NARROW [EC:2.7.7.6] +synonym: "RNA polymerase II activity" NARROW [EC:2.7.7.6] +synonym: "RNA polymerase III activity" NARROW [EC:2.7.7.6] +synonym: "transcriptase" BROAD [EC:2.7.7.6] +xref: EC:2.7.7.6 +xref: MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN +xref: Reactome:R-HSA-111264 "Addition of nucleotides between position +11 and +30" +xref: Reactome:R-HSA-167113 "Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition" +xref: Reactome:R-HSA-167115 "Addition of nucleotides between position +11 and +30 on HIV-1 transcript" +xref: Reactome:R-HSA-167117 "Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition" +xref: Reactome:R-HSA-167121 "Addition of the third nucleotide on the nascent HIV-1 transcript" +xref: Reactome:R-HSA-167136 "Addition of nucleotides 5 through 9 on the growing HIV-1 transcript" +xref: Reactome:R-HSA-174425 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere" +xref: Reactome:R-HSA-203901 "Pol II mediated transcription of microRNA genes" +xref: Reactome:R-HSA-427366 "Transcription of intergenic spacer of the rRNA gene" +xref: Reactome:R-HSA-5601926 "RNA polymerase II polymerizes primary piRNA transcript" +xref: Reactome:R-HSA-6781824 "Active RNA Pol II complex transcribes lesion-containing DNA template" +xref: Reactome:R-HSA-68913 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin" +xref: Reactome:R-HSA-74986 "Elongation of pre-rRNA transcript" +xref: Reactome:R-HSA-75850 "Addition of the third nucleotide on the nascent transcript" +xref: Reactome:R-HSA-75869 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition" +xref: Reactome:R-HSA-75873 "Addition of Nucleotides 5 through 9 on the growing Transcript" +xref: Reactome:R-HSA-76576 "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition" +is_a: GO:0034062 ! 5'-3' RNA polymerase activity +relationship: part_of GO:0032774 ! RNA biosynthetic process + +[Term] +id: GO:0003900 +name: obsolete DNA-directed RNA polymerase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.6] +comment: This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase I complex ; GO:0005736'. +synonym: "DNA-directed RNA polymerase I activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003899 + +[Term] +id: GO:0003901 +name: obsolete DNA-directed RNA polymerase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.6] +comment: This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase II, core complex ; GO:0005665'. +synonym: "DNA-directed RNA polymerase II activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003899 + +[Term] +id: GO:0003902 +name: obsolete DNA-directed RNA polymerase III activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.6] +comment: This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase III complex ; GO:0005666'. +synonym: "DNA-directed RNA polymerase III activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003899 + +[Term] +id: GO:0003904 +name: deoxyribodipyrimidine photo-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light." [EC:4.1.99.3] +synonym: "CPD photolyase activity" EXACT [PMID:16302973] +synonym: "deoxyribocyclobutadipyrimidine pyrimidine-lyase activity" EXACT [EC:4.1.99.3] +synonym: "deoxyribodipyrimidine photolyase activity" EXACT [] +synonym: "deoxyribonucleate pyrimidine dimer lyase (photosensitive)" EXACT [EC:4.1.99.3] +synonym: "deoxyribonucleic cyclobutane dipyrimidine photolyase activity" EXACT [EC:4.1.99.3] +synonym: "deoxyribonucleic photolyase activity" EXACT [EC:4.1.99.3] +synonym: "dipyrimidine photolyase (photosensitive)" EXACT [EC:4.1.99.3] +synonym: "DNA cyclobutane dipyrimidine photolyase activity" EXACT [EC:4.1.99.3] +synonym: "DNA-photoreactivating enzyme" RELATED [EC:4.1.99.3] +synonym: "photolyase activity" EXACT [EC:4.1.99.3] +synonym: "photoreactivating enzyme activity" RELATED [EC:4.1.99.3] +synonym: "phr A photolyase activity" EXACT [EC:4.1.99.3] +synonym: "PhrB photolyase activity" EXACT [EC:4.1.99.3] +synonym: "PRE" RELATED [EC:4.1.99.3] +xref: EC:4.1.99.3 +xref: MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN +xref: RHEA:10672 +is_a: GO:0003913 ! DNA photolyase activity + +[Term] +id: GO:0003905 +name: alkylbase DNA N-glycosylase activity +namespace: molecular_function +alt_id: GO:0004036 +def: "Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623] +synonym: "3-methyladenine DNA glycosylase II" RELATED [EC:3.2.2.21] +synonym: "AlkA" RELATED [EC:3.2.2.21] +synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.21] +synonym: "alkylbase DNA glycosidase activity" EXACT [] +synonym: "deoxyribonucleate 3-methyladenine glycosidase II" RELATED [EC:3.2.2.21] +synonym: "DNA glycosidase II activity" EXACT [EC:3.2.2.21] +synonym: "DNA-3-methyladenine glycosidase II activity" EXACT [] +synonym: "DNA-3-methyladenine glycosylase II" RELATED [EC:3.2.2.21] +xref: EC:3.2.2.21 +xref: MetaCyc:3.2.2.21-RXN +is_a: GO:0019104 ! DNA N-glycosylase activity + +[Term] +id: GO:0003906 +name: DNA-(apurinic or apyrimidinic site) endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER)." [Wikipedia:AP_endonuclease] +synonym: "abasic deoxyendoribonuclease activity" EXACT [] +synonym: "AP deoxyendoribonuclease activity" EXACT [] +synonym: "apurinic deoxyendoribonuclease activity" EXACT [] +synonym: "apurinic/apyrimidinic endodeoxyribonuclease activity" EXACT [] +synonym: "apyrimidinic deoxyendoribonuclease activity" EXACT [] +synonym: "deoxyribonuclease (apurinic or apyrimidinic) activity" EXACT [] +synonym: "endonuclease VIII activity" RELATED [] +synonym: "UV endonuclease" BROAD [] +xref: Reactome:R-HSA-110375 "Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break" +xref: Reactome:R-HSA-5649711 "NEIL1,NEIL2 incises DNA strand 5' to the AP site" +xref: Reactome:R-HSA-5649725 "POLB excises the NEIL1,NEIL2-bound AP site (5'dRP)" +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0003908 +name: methylated-DNA-[protein]-cysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine." [EC:2.1.1.63] +synonym: "6-O-methylguanine-DNA methyltransferase activity" EXACT [EC:2.1.1.63] +synonym: "DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity" EXACT [] +synonym: "DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity" EXACT [EC:2.1.1.63] +synonym: "methylated-DNA-protein-cysteine S-methyltransferase activity" EXACT [EC:2.1.1.63] +synonym: "MGMT" EXACT [] +synonym: "O-6-methylguanine-DNA-alkyltransferase activity" EXACT [EC:2.1.1.63] +synonym: "O6-alkylguanine-DNA alkyltransferase" BROAD [] +xref: EC:2.1.1.63 +xref: MetaCyc:2.1.1.63-RXN +xref: Reactome:R-HSA-73892 "MGMT/hAGT mediated DNA Damage Reversal" +is_a: GO:0008172 ! S-methyltransferase activity + +[Term] +id: GO:0003909 +name: DNA ligase activity +namespace: molecular_function +def: "Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+." [ISBN:0716720094] +xref: Reactome:R-HSA-174456 "Joining of adjacent Okazaki fragments of the C-strand" +xref: Reactome:R-HSA-175258 "2-LTR formation due to circularization of viral DNA" +xref: Reactome:R-HSA-5358592 "DNA ligase I ligates single stranded nick in double stranded DNA" +xref: Reactome:R-HSA-5649734 "LIG3 ligates NEIL1,NEIL2-generated single strand break" +xref: Reactome:R-HSA-5651789 "LIG1 bound to POLB ligates SSB" +xref: Reactome:R-HSA-5651805 "LIG1 bound to APEX1 and PCNA ligates SSB" +xref: Reactome:R-HSA-5687675 "LIG3 ligates remaining SSBs in MMEJ" +xref: Reactome:R-HSA-5690997 "Ligation of newly synthesized repair patch to incised DNA in GG-NER" +xref: Reactome:R-HSA-5693604 "XRCC4:LIG4 ligates DNA DSB ends during NHEJ" +xref: Reactome:R-HSA-6782227 "Ligation of newly synthesized repair patch to incised DNA in TC-NER" +xref: Reactome:R-HSA-69173 "Joining of adjacent Okazaki fragments" +xref: Reactome:R-HSA-73931 "LIG3-mediated DNA ligation via the single-nucleotide replacement pathway" +is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0006266 ! DNA ligation + +[Term] +id: GO:0003910 +name: DNA ligase (ATP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m)." [EC:6.5.1.1] +synonym: "deoxyribonucleate ligase" BROAD [EC:6.5.1.1] +synonym: "deoxyribonucleic acid joinase" BROAD [EC:6.5.1.1] +synonym: "deoxyribonucleic acid ligase" BROAD [EC:6.5.1.1] +synonym: "deoxyribonucleic acid repair enzyme" RELATED [EC:6.5.1.1] +synonym: "deoxyribonucleic acid-joining enzyme" RELATED [EC:6.5.1.1] +synonym: "deoxyribonucleic joinase" BROAD [EC:6.5.1.1] +synonym: "deoxyribonucleic ligase" BROAD [EC:6.5.1.1] +synonym: "deoxyribonucleic repair enzyme" RELATED [EC:6.5.1.1] +synonym: "deoxyribonucleic-joining enzyme" RELATED [EC:6.5.1.1] +synonym: "DNA joinase activity" BROAD [EC:6.5.1.1] +synonym: "DNA repair enzyme activity" RELATED [EC:6.5.1.1] +synonym: "DNA-joining enzyme" RELATED [EC:6.5.1.1] +synonym: "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)" EXACT [EC:6.5.1.1] +synonym: "polydeoxyribonucleotide synthase (ATP) activity" EXACT [EC:6.5.1.1] +synonym: "polynucleotide ligase" BROAD [EC:6.5.1.1] +synonym: "polynucleotide ligase (ATP) activity" EXACT [EC:6.5.1.1] +synonym: "sealase activity" RELATED [EC:6.5.1.1] +xref: EC:6.5.1.1 +xref: MetaCyc:DNA-LIGASE-ATP-RXN +is_a: GO:0003909 ! DNA ligase activity + +[Term] +id: GO:0003911 +name: DNA ligase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m)." [EC:6.5.1.2] +synonym: "deoxyribonucleate ligase" BROAD [EC:6.5.1.2] +synonym: "deoxyribonucleic acid joinase" BROAD [EC:6.5.1.2] +synonym: "deoxyribonucleic acid ligase" BROAD [EC:6.5.1.2] +synonym: "deoxyribonucleic joinase" BROAD [EC:6.5.1.2] +synonym: "deoxyribonucleic ligase" BROAD [EC:6.5.1.2] +synonym: "deoxyribonucleic repair enzyme" RELATED [EC:6.5.1.2] +synonym: "deoxyribonucleic-joining enzyme" RELATED [EC:6.5.1.2] +synonym: "DNA joinase activity" BROAD [EC:6.5.1.2] +synonym: "DNA ligase (NAD)" EXACT [EC:6.5.1.2] +synonym: "DNA repair enzyme activity" RELATED [EC:6.5.1.2] +synonym: "DNA-joining enzyme" RELATED [EC:6.5.1.2] +synonym: "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)" EXACT [EC:6.5.1.2] +synonym: "Polydeoxyribonucleotide synthase (NAD(+)) activity" EXACT [EC:6.5.1.2] +synonym: "polydeoxyribonucleotide synthase (NAD)" EXACT [EC:6.5.1.2] +synonym: "polydeoxyribonucleotide synthase (NAD+) activity" EXACT [EC:6.5.1.2] +synonym: "polynucleotide ligase" BROAD [EC:6.5.1.2] +synonym: "polynucleotide ligase (NAD(+)) activity" EXACT [EC:6.5.1.2] +synonym: "polynucleotide ligase (NAD)" EXACT [EC:6.5.1.2] +synonym: "polynucleotide ligase (NAD+) activity" EXACT [EC:6.5.1.2] +synonym: "polynucleotide ligase (nicotinamide adenine dinucleotide)" EXACT [EC:6.5.1.2] +synonym: "polynucleotide synthetase (nicotinamide adenine dinucleotide)" EXACT [EC:6.5.1.2] +synonym: "polynucleotide synthetase activity" EXACT [EC:6.5.1.2] +xref: EC:6.5.1.2 +xref: MetaCyc:DNA-LIGASE-NAD+-RXN +is_a: GO:0003909 ! DNA ligase activity + +[Term] +id: GO:0003912 +name: DNA nucleotidylexotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)." [EC:2.7.7.31] +synonym: "addase activity" EXACT [EC:2.7.7.31] +synonym: "deoxynucleotidyl terminal transferase activity" EXACT [EC:2.7.7.31] +synonym: "deoxyribonucleic acid nucleotidyltransferase activity" EXACT [EC:2.7.7.31] +synonym: "deoxyribonucleic nucleotidyltransferase activity" EXACT [EC:2.7.7.31] +synonym: "nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [EC:2.7.7.31] +synonym: "TdT" RELATED [EC:2.7.7.31] +synonym: "terminal addition enzyme activity" RELATED [EC:2.7.7.31] +synonym: "terminal deoxynucleotide transferase activity" EXACT [EC:2.7.7.31] +synonym: "terminal deoxynucleotidyltransferase activity" EXACT [EC:2.7.7.31] +synonym: "terminal deoxyribonucleotidyltransferase activity" EXACT [EC:2.7.7.31] +synonym: "terminal transferase activity" EXACT [EC:2.7.7.31] +xref: EC:2.7.7.31 +xref: MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0003913 +name: DNA photolyase activity +namespace: molecular_function +def: "Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA." [GOC:mah, PMID:11124949] +xref: MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN +is_a: GO:0016830 ! carbon-carbon lyase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0003914 +name: DNA (6-4) photolyase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA." [GOC:mah, PMID:11124949] +xref: EC:4.1.99.13 +xref: MetaCyc:RXN-10771 +is_a: GO:0003913 ! DNA photolyase activity + +[Term] +id: GO:0003916 +name: DNA topoisomerase activity +namespace: molecular_function +alt_id: GO:0009387 +def: "Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA." [GOC:mah, PMID:8811192] +xref: EC:5.6.2 +is_a: GO:0016853 ! isomerase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: has_part GO:0003677 ! DNA binding + +[Term] +id: GO:0003917 +name: DNA topoisomerase type I (single strand cut, ATP-independent) activity +namespace: molecular_function +def: "Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle." [PMID:8811192] +comment: Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity. +synonym: "deoxyribonucleate topoisomerase" BROAD [] +synonym: "DNA topoisomerase I activity" NARROW [] +synonym: "nicking-closing enzyme activity" RELATED [EC:5.6.2.1] +synonym: "omega-protein activity" RELATED [EC:5.6.2.1] +synonym: "relaxing enzyme activity" RELATED [EC:5.6.2.1] +synonym: "swivelase activity" RELATED [EC:5.6.2.1] +synonym: "topoisomerase" BROAD [EC:5.6.2.1] +synonym: "type I DNA topoisomerase activity" EXACT [] +synonym: "type I topoisomerase activity" EXACT [] +synonym: "untwisting enzyme activity" RELATED [EC:5.6.2.1] +xref: EC:5.6.2.1 +xref: MetaCyc:5.99.1.2-RXN +is_a: GO:0003916 ! DNA topoisomerase activity + +[Term] +id: GO:0003918 +name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +namespace: molecular_function +alt_id: GO:0061505 +def: "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192] +synonym: "deoxyribonucleate topoisomerase" BROAD [GOC:krc] +synonym: "deoxyribonucleic topoisomerase activity" BROAD [EC:5.6.2.2, GOC:krc] +synonym: "DNA topoisomerase (ATP-hydrolysing)" EXACT [EC:5.6.2.2, GOC:krc] +synonym: "DNA topoisomerase II" NARROW [EC:5.6.2.2, GOC:krc] +synonym: "DNA topoisomerase II activity" NARROW [GOC:krc] +synonym: "DNA topoisomerase IV activity" NARROW [GOC:krc] +synonym: "DNA topoisomerase type II activity" EXACT [GOC:krc] +synonym: "topoisomerase" BROAD [EC:5.6.2.2, GOC:krc] +synonym: "topoisomerase II" NARROW [GOC:krc] +synonym: "type II DNA topoisomerase activity" EXACT [EC:5.6.2.2, GOC:krc] +xref: EC:5.6.2.2 +xref: MetaCyc:5.99.1.3-RXN +xref: Wikipedia:Type_II_topoisomerase +is_a: GO:0003916 ! DNA topoisomerase activity +is_a: GO:0008094 ! DNA-dependent ATPase activity + +[Term] +id: GO:0003919 +name: FMN adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + FMN = diphosphate + FAD." [EC:2.7.7.2, RHEA:17237] +synonym: "adenosine triphosphate-riboflavin mononucleotide transadenylase activity" EXACT [EC:2.7.7.2] +synonym: "adenosine triphosphate-riboflavine mononucleotide transadenylase activity" EXACT [EC:2.7.7.2] +synonym: "ATP:FMN adenylyltransferase activity" EXACT [] +synonym: "FAD diphosphorylase activity" EXACT [EC:2.7.7.2] +synonym: "FAD pyrophosphorylase activity" EXACT [EC:2.7.7.2] +synonym: "FAD synthetase activity" EXACT [EC:2.7.7.2] +synonym: "flavin adenine dinucleotide synthetase activity" EXACT [EC:2.7.7.2] +synonym: "riboflavin adenine dinucleotide pyrophosphorylase activity" EXACT [EC:2.7.7.2] +synonym: "riboflavin mononucleotide adenylyltransferase activity" EXACT [EC:2.7.7.2] +synonym: "riboflavine adenine dinucleotide adenylyltransferase activity" EXACT [EC:2.7.7.2] +xref: EC:2.7.7.2 +xref: KEGG_REACTION:R00161 +xref: MetaCyc:FADSYN-RXN +xref: Reactome:R-HSA-196929 "FLAD1 phosphorylates FMN" +xref: RHEA:17237 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0003920 +name: GMP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH." [EC:1.7.1.7, RHEA:17185] +comment: Note that this function was formerly EC:1.6.6.8. +synonym: "guanosine 5'-monophosphate oxidoreductase activity" EXACT [EC:1.7.1.7] +synonym: "guanosine 5'-monophosphate reductase activity" EXACT [EC:1.7.1.7] +synonym: "guanosine 5'-phosphate reductase activity" EXACT [EC:1.7.1.7] +synonym: "guanosine monophosphate reductase activity" EXACT [EC:1.7.1.7] +synonym: "guanylate reductase activity" RELATED [EC:1.7.1.7] +synonym: "inosine-5'-phosphate:NADP+ oxidoreductase (aminating)" EXACT [EC:1.7.1.7] +synonym: "NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)" EXACT [EC:1.7.1.7] +synonym: "NADPH:GMP oxidoreductase (deaminating) activity" EXACT [EC:1.7.1.7] +synonym: "NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity" EXACT [EC:1.7.1.7] +xref: EC:1.7.1.7 +xref: KEGG_REACTION:R01134 +xref: MetaCyc:GMP-REDUCT-RXN +xref: Reactome:R-HSA-514604 "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)" +xref: RHEA:17185 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0003921 +name: GMP synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+)." [RHEA:18301] +xref: MetaCyc:GMP-SYN-NH3-RXN +xref: RHEA:18301 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +relationship: part_of GO:0003922 ! GMP synthase (glutamine-hydrolyzing) activity + +[Term] +id: GO:0003922 +name: GMP synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+)." [RHEA:11680] +synonym: "glutamine amidotransferase activity" EXACT [EC:6.3.5.2] +synonym: "GMP synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.2] +synonym: "GMP synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.2] +synonym: "GMP synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.2] +synonym: "guanosine 5'-monophosphate synthetase activity" EXACT [EC:6.3.5.2] +synonym: "guanosine monophosphate synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.2] +synonym: "guanylate synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.2] +synonym: "xanthosine 5'-phosphate amidotransferase activity" EXACT [EC:6.3.5.2] +synonym: "xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.2] +xref: EC:6.3.5.2 +xref: MetaCyc:GMP-SYN-GLUT-RXN +xref: Reactome:R-HSA-73792 "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate" +xref: RHEA:11680 +xref: Wikipedia:GMP_synthase_(glutamine-hydrolysing) +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor +relationship: part_of GO:0006177 ! GMP biosynthetic process + +[Term] +id: GO:0003923 +name: GPI-anchor transamidase activity +namespace: molecular_function +def: "Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor." [ISBN:0471331309] +xref: Reactome:R-HSA-162836 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide" +is_a: GO:0016787 ! hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0003924 +name: GTPase activity +namespace: molecular_function +alt_id: GO:0061745 +def: "Catalysis of the reaction: GTP + H2O = GDP + phosphate." [ISBN:0198547684, PMID:26832457, PMID:27218782] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "ARF small monomeric GTPase activity" NARROW [] +synonym: "dynamin GTPase activity" NARROW [] +synonym: "GTPase activity, coupled" RELATED [] +synonym: "heterotrimeric G-protein GTPase activity" NARROW [] +synonym: "heterotrimeric G-protein GTPase, alpha-subunit" RELATED [] +synonym: "heterotrimeric G-protein GTPase, beta-subunit" RELATED [] +synonym: "heterotrimeric G-protein GTPase, gamma-subunit" RELATED [] +synonym: "hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement" BROAD [] +synonym: "protein-synthesizing GTPase activity" NARROW [] +synonym: "protein-synthesizing GTPase activity, elongation" NARROW [] +synonym: "protein-synthesizing GTPase activity, initiation" NARROW [] +synonym: "protein-synthesizing GTPase activity, termination" NARROW [] +synonym: "Rab small monomeric GTPase activity" NARROW [] +synonym: "Ran small monomeric GTPase activity" NARROW [] +synonym: "Ras small monomeric GTPase activity" NARROW [] +synonym: "RHEB small monomeric GTPase activity" NARROW [] +synonym: "Rho small monomeric GTPase activity" NARROW [] +synonym: "Sar small monomeric GTPase activity" NARROW [] +synonym: "signal-recognition-particle GTPase activity" NARROW [] +synonym: "small monomeric GTPase activity" NARROW [] +synonym: "tubulin GTPase activity" NARROW [] +xref: Reactome:R-HSA-1445143 "RAB8A,10,13,14 hydrolyze GTP" +xref: Reactome:R-HSA-1458485 "RALA hydrolyzes GTP" +xref: Reactome:R-HSA-156923 "Hydrolysis of eEF1A:GTP" +xref: Reactome:R-HSA-164381 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP" +xref: Reactome:R-HSA-165055 "Hydrolysis of Ran:GTP to Ran:GDP" +xref: Reactome:R-HSA-167415 "G-protein alpha subunit is inactivated" +xref: Reactome:R-HSA-170666 "Adenylate cyclase increases the GTPase activity of G alpha-olf" +xref: Reactome:R-HSA-170685 "Adenylaye cyclase increases the GTPase activity of G alpha-olf" +xref: Reactome:R-HSA-170686 "Adenylate cyclase increases the GTPase activity of Gi alpha" +xref: Reactome:R-HSA-177501 "Endocytosis (internalization) of clathrin-coated vesicle" +xref: Reactome:R-HSA-203973 "Vesicle budding" +xref: Reactome:R-HSA-2130641 "Translocation of TGN-lysosome vesicle to lysosome" +xref: Reactome:R-HSA-2130725 "Internalization of MHC II:Ii clathrin coated vesicle" +xref: Reactome:R-HSA-2584246 "GNAT1-GTP hydrolyses its bound GTP to GDP" +xref: Reactome:R-HSA-380979 "RHEB in mTORC1:RHEB:GTP hydrolyses GTP" +xref: Reactome:R-HSA-392133 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP" +xref: Reactome:R-HSA-392212 "G alpha (i) auto-inactivates by hydrolysing GTP to GDP" +xref: Reactome:R-HSA-418574 "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP" +xref: Reactome:R-HSA-418582 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP" +xref: Reactome:R-HSA-421835 "trans-Golgi Network Vesicle Scission" +xref: Reactome:R-HSA-428941 "P2Y purinoceptor 1 activates MAP kinase p38 alpha" +xref: Reactome:R-HSA-432707 "trans-Golgi Network Lysosomal Vesicle Scission" +xref: Reactome:R-HSA-5333615 "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC" +xref: Reactome:R-HSA-5389839 "39S subunit binds 28S subunit:mRNA:fMet-tRNA" +xref: Reactome:R-HSA-5389842 "TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome" +xref: Reactome:R-HSA-5419273 "Hydrolysis of GTP and dissociation of 28S and 39S subunits" +xref: Reactome:R-HSA-5419279 "Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)" +xref: Reactome:R-HSA-555065 "Formation of clathrin coated vesicle" +xref: Reactome:R-HSA-5623513 "ASAP1 stimulates GTPase activity of ARF4" +xref: Reactome:R-HSA-5638006 "ARL3 hydrolyzes GTP" +xref: Reactome:R-HSA-5658231 "RAS GAPs stimulate RAS GTPase activity" +xref: Reactome:R-HSA-5665809 "SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments" +xref: Reactome:R-HSA-5672017 "Rheb in the mTORC1 complex hydrolyses GTP" +xref: Reactome:R-HSA-5694527 "Loss of SAR1B GTPase" +xref: Reactome:R-HSA-6807877 "ARFGAPs stimulate ARF GTPase activity" +xref: Reactome:R-HSA-6814833 "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP" +xref: Reactome:R-HSA-8847534 "RAB43 hydrolyses GTP" +xref: Reactome:R-HSA-8847883 "CYTH proteins stimulate ARF1 GTPase activity" +xref: Reactome:R-HSA-8849082 "ARHGAP35 stimulates RHOA GTPase activity" +xref: Reactome:R-HSA-8854173 "TBC RabGAPs accelerate GTP hydrolysis by RAB35" +xref: Reactome:R-HSA-8854255 "TBC1D2A accelerates GTP hydrolysis by RAB7" +xref: Reactome:R-HSA-8854329 "TBC1D15 accelerates GTP hydrolysis by RAB7" +xref: Reactome:R-HSA-8854604 "TBC1D16 accelerates GTP hydrolysis by RAB4A" +xref: Reactome:R-HSA-8854612 "TBC1D25 accelerates GTP hydrolysis by RAB33B" +xref: Reactome:R-HSA-8868661 "Dynamin-mediated GTP hydrolysis promotes vesicle scission" +xref: Reactome:R-HSA-8981353 "RASA1 stimulates RAS GTPase activity" +xref: Reactome:R-HSA-8982020 "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated" +xref: Reactome:R-HSA-8982021 "G alpha (z) in G alpha (z):RGS complex is inactivated" +xref: Reactome:R-HSA-8982025 "G alpha (q) in G (q):RGS complex is inactivated" +xref: Reactome:R-HSA-983422 "Disassembly of COPII coated vesicle" +xref: RHEA:19669 +is_a: GO:0017111 ! nucleoside-triphosphatase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19078 xsd:anyURI +created_by: dph +creation_date: 2015-11-11T12:47:56Z + +[Term] +id: GO:0003925 +name: obsolete small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Small monomeric enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of heterotrimeric G-protein GTPase. They are involved in cell-growth regulation (RAS subfamily), membrane vesicle traffic and uncoating (RAB and ARF subfamilies), nuclear protein import (RAN subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies)." [EC:3.6.5.2, GOC:mah, ISBN:0198547684, MetaCyc:3.6.1.47-RXN] +comment: This term was made obsolete because it represents a gene product and contains cellular component information. +synonym: "small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 + +[Term] +id: GO:0003926 +name: obsolete ARF small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "ARF small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0016191 +consider: GO:0016192 + +[Term] +id: GO:0003927 +name: obsolete heterotrimeric G-protein GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GTP-hydrolyzing enzymes, where GTP and GDP alternate in binding. Includes stimulatory and inhibitory G-proteins such as Gs, Gi, Go and Golf, targeting adenylate cyclase and/or potassium ion and calcium ion channels; Gq stimulating phospholipase C; transducin activating cGMP phosphodiesterase; gustducin activating cAMP phosphodiesterase." [EC:3.6.5.1, ISBN:0198547684, MetaCyc:3.6.1.46-RXN] +comment: This term was made obsolete because it represents a cellular component. +synonym: "heterotrimeric G-protein GTPase activity" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0005834 + +[Term] +id: GO:0003928 +name: obsolete RAB small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "RAB small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0016191 +consider: GO:0016192 + +[Term] +id: GO:0003929 +name: obsolete RAN small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "RAN small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0006606 + +[Term] +id: GO:0003930 +name: obsolete RAS small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "RAS small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0001558 + +[Term] +id: GO:0003931 +name: obsolete Rho small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton." [EC:3.6.1.47, GOC:mah, ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "Rho small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0007010 + +[Term] +id: GO:0003932 +name: obsolete SAR small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47] +comment: This term was made obsolete because it represents a gene product. +synonym: "SAR small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0046903 + +[Term] +id: GO:0003933 +name: GTP cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized." [EC:3.5.4.16, EC:3.5.4.25, EC:3.5.4.29, GOC:curators] +is_a: GO:0019238 ! cyclohydrolase activity + +[Term] +id: GO:0003934 +name: GTP cyclohydrolase I activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate." [EC:3.5.4.16] +synonym: "dihydroneopterin triphosphate synthase activity" EXACT [EC:3.5.4.16] +synonym: "GTP 7,8-8,9-dihydrolase activity" EXACT [EC:3.5.4.16] +synonym: "GTP 8-formylhydrolase activity" EXACT [EC:3.5.4.16] +synonym: "guanosine triphosphate 8-deformylase activity" EXACT [EC:3.5.4.16] +synonym: "guanosine triphosphate cyclohydrolase activity" EXACT [EC:3.5.4.16] +xref: EC:3.5.4.16 +xref: KEGG_REACTION:R00424 +xref: MetaCyc:GTP-CYCLOHYDRO-I-RXN +xref: Reactome:R-HSA-1474146 "GCH1 reduces GTP to dihydroneopterin triphosphate" +xref: RHEA:17473 +is_a: GO:0003933 ! GTP cyclohydrolase activity + +[Term] +id: GO:0003935 +name: GTP cyclohydrolase II activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+)." [EC:3.5.4.25, RHEA:23704] +synonym: "GTP 7,8-8,9-dihydrolase (diphosphate-forming)" EXACT [EC:3.5.4.25] +synonym: "GTP-8-formylhydrolase activity" EXACT [EC:3.5.4.25] +synonym: "guanosine triphosphate cyclohydrolase II" RELATED [EC:3.5.4.25] +xref: EC:3.5.4.25 +xref: KEGG_REACTION:R00425 +xref: MetaCyc:GTP-CYCLOHYDRO-II-RXN +xref: RHEA:23704 +is_a: GO:0003933 ! GTP cyclohydrolase activity + +[Term] +id: GO:0003936 +name: obsolete hydrogen-transporting two-sector ATPase activity +namespace: molecular_function +alt_id: GO:0004006 +alt_id: GO:0008729 +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)." [EC:3.6.3.14, TC:3.A.3.-.-] +comment: This term was made obsolete because it refers to a bifunctional gene product. +synonym: "hydrogen-transporting two-sector ATPase activity" EXACT [] +synonym: "proton-transporting two-sector ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0046933 +consider: GO:0046961 + +[Term] +id: GO:0003937 +name: IMP cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide." [EC:3.5.4.10] +synonym: "IMP 1,2-hydrolase (decyclizing)" EXACT [EC:3.5.4.10] +synonym: "IMP synthetase activity" EXACT [EC:3.5.4.10] +synonym: "inosinate cyclohydrolase activity" EXACT [EC:3.5.4.10] +synonym: "inosinicase activity" EXACT [EC:3.5.4.10] +xref: EC:3.5.4.10 +xref: MetaCyc:IMPCYCLOHYDROLASE-RXN +xref: Reactome:R-HSA-73797 "FAICAR => IMP + H2O" +xref: RHEA:18445 +is_a: GO:0019238 ! cyclohydrolase activity + +[Term] +id: GO:0003938 +name: IMP dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+." [EC:1.1.1.205] +synonym: "IMP oxidoreductase activity" EXACT [EC:1.1.1.205] +synonym: "IMP:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.205] +synonym: "inosinate dehydrogenase activity" RELATED [EC:1.1.1.205] +synonym: "inosine 5'-monophosphate dehydrogenase activity" EXACT [EC:1.1.1.205] +synonym: "inosine monophosphate dehydrogenase activity" EXACT [EC:1.1.1.205] +synonym: "inosine monophosphate oxidoreductase activity" EXACT [EC:1.1.1.205] +synonym: "inosine-5'-phosphate dehydrogenase activity" EXACT [EC:1.1.1.205] +synonym: "inosinic acid dehydrogenase activity" RELATED [EC:1.1.1.205] +xref: EC:1.1.1.205 +xref: MetaCyc:IMP-DEHYDROG-RXN +xref: Reactome:R-HSA-73794 "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]" +xref: RHEA:11708 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003939 +name: L-iditol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+." [EC:1.1.1.14] +comment: Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols. +synonym: "glucitol dehydrogenase activity" RELATED [EC:1.1.1.14] +synonym: "L-iditol (sorbitol) dehydrogenase activity" RELATED [EC:1.1.1.14] +synonym: "L-iditol:NAD oxidoreductase activity" EXACT [EC:1.1.1.14] +synonym: "L-iditol:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.14] +synonym: "NAD+-dependent sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] +synonym: "NAD-dependent sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] +synonym: "NAD-sorbitol dehydrogenase" RELATED [EC:1.1.1.14] +synonym: "polyol dehydrogenase activity" BROAD [EC:1.1.1.14] +synonym: "sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] +xref: EC:1.1.1.14 +xref: MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-5652195 "SORD oxidizes D-sorbitol to Fru" +xref: RHEA:10160 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003940 +name: L-iduronidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate." [EC:3.2.1.76] +synonym: "alpha-L-iduronidase activity" EXACT [EC:3.2.1.76] +synonym: "glycosaminoglycan alpha-L-iduronohydrolase activity" EXACT [EC:3.2.1.76] +xref: EC:3.2.1.76 +xref: MetaCyc:3.2.1.76-RXN +xref: Reactome:R-HSA-1678716 "IDUA hydrolyses Heparan sulfate chain(1)" +xref: Reactome:R-HSA-1793186 "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS" +xref: Reactome:R-HSA-2090037 "IDUA hydrolyses Heparan sulfate chain(6)" +xref: Reactome:R-HSA-2206299 "Defective IDUA does not hydrolyse Heparan sulfate chain(6)" +xref: Reactome:R-HSA-9036037 "Defective IDUA does not hydrolyse Heparan sulfate chain(1)" +xref: Reactome:R-HSA-9036041 "Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0003941 +name: L-serine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine = pyruvate + NH3." [EC:4.3.1.17] +comment: Note that this function was formerly EC:4.3.1.13. +synonym: "L-hydroxyaminoacid dehydratase activity" BROAD [] +synonym: "L-serine ammonia-lyase (pyruvate-forming) activity" EXACT [EC:4.3.1.17] +synonym: "L-serine deaminase activity" EXACT [] +synonym: "L-serine dehydratase activity" BROAD [EC:4.3.1.17] +synonym: "L-serine hydro-lyase (deaminating) activity" EXACT [] +synonym: "serine deaminase activity" BROAD [EC:4.3.1.17] +xref: EC:4.3.1.17 +xref: MetaCyc:4.3.1.17-RXN +xref: RHEA:19169 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0003942 +name: N-acetyl-gamma-glutamyl-phosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+." [EC:1.2.1.38] +synonym: "N-acetyl-glutamate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] +synonym: "N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.38] +synonym: "N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.38] +synonym: "N-acetylglutamate 5-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] +synonym: "N-acetylglutamic gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] +synonym: "NAGSA dehydrogenase activity" BROAD [EC:1.2.1.38] +synonym: "reductase, acetyl-gamma-glutamyl phosphate" EXACT [EC:1.2.1.38] +xref: EC:1.2.1.38 +xref: MetaCyc:N-ACETYLGLUTPREDUCT-RXN +xref: RHEA:21588 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003943 +name: N-acetylgalactosamine-4-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate." [EC:3.1.6.12] +synonym: "acetylgalactosamine 4-sulfatase activity" EXACT [EC:3.1.6.12] +synonym: "arylsulfatase B" EXACT [] +synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.12] +synonym: "N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity" EXACT [EC:3.1.6.12] +synonym: "N-acetylgalactosamine 4-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.12] +synonym: "N-acetylgalactosamine-4-sulphatase activity" EXACT [] +xref: EC:3.1.6.12 +xref: MetaCyc:3.1.6.12-RXN +xref: Reactome:R-HSA-1606789 "ARSB hydrolyses DS" +xref: Reactome:R-HSA-1793207 "ARSB hydrolyses C4S/C6S chains" +xref: Reactome:R-HSA-2282889 "Defective ARSB does not hydrolyse C4S/C6S chains" +xref: Reactome:R-HSA-9036065 "Defective ARSB does not hydrolyse DS" +xref: Wikipedia:Arylsulfatase_B +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0003944 +name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose." [EC:3.1.4.45] +synonym: "2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity" EXACT [EC:3.1.4.45] +synonym: "alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity" EXACT [EC:3.1.4.45] +synonym: "alpha-N-acetylglucosaminyl phosphodiesterase activity" EXACT [EC:3.1.4.45] +synonym: "glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity" EXACT [EC:3.1.4.45] +synonym: "lysosomal alpha-N-acetylglucosaminidase activity" NARROW [EC:3.1.4.45] +synonym: "phosphodiester glycosidase activity" EXACT [EC:3.1.4.45] +xref: EC:3.1.4.45 +xref: MetaCyc:3.1.4.45-RXN +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0003945 +name: N-acetyllactosamine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine." [EC:2.4.1.90] +synonym: "acetyllactosamine synthetase activity" EXACT [EC:2.4.1.90] +synonym: "beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "beta-1,4-GalT" RELATED [EC:2.4.1.90] +synonym: "beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "Gal-T" RELATED [EC:2.4.1.90] +synonym: "lactosamine synthase activity" EXACT [EC:2.4.1.90] +synonym: "lactosamine synthetase activity" EXACT [EC:2.4.1.90] +synonym: "lactose synthetase A protein" RELATED [EC:2.4.1.90] +synonym: "N-acetylglucosamine (beta-1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "N-acetylglucosamine beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "N-acetyllactosamine synthetase activity" EXACT [EC:2.4.1.90] +synonym: "NAL synthetase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose-N-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] +synonym: "uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] +xref: EC:2.4.1.90 +xref: MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN +xref: RHEA:17745 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0003947 +name: (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide." [EC:2.4.1.92] +synonym: "asialo-GM2 synthase activity" EXACT [EC:2.4.1.92] +synonym: "beta-1,4N-aetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "GalNAc-T activity" EXACT [EC:2.4.1.92] +synonym: "ganglioside GM2 synthase activity" EXACT [EC:2.4.1.92] +synonym: "ganglioside GM3 acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "GM2 synthase activity" EXACT [EC:2.4.1.92] +synonym: "GM2/GD2-synthase activity" EXACT [EC:2.4.1.92] +synonym: "UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +synonym: "uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] +xref: EC:2.4.1.92 +xref: MetaCyc:2.4.1.92-RXN +xref: Reactome:R-HSA-8856223 "B4GALNT1 dimer transfers GalNAc from UDP-GalNAc to GM3 and GD3 gangliosides" +xref: RHEA:12588 +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0003948 +name: N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)." [EC:3.5.1.26, RHEA:11544] +synonym: "4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.26] +synonym: "aspartylglucosaminidase activity" EXACT [EC:3.5.1.26] +synonym: "aspartylglucosylaminase activity" EXACT [EC:3.5.1.26] +synonym: "aspartylglucosylamine deaspartylase activity" EXACT [EC:3.5.1.26] +synonym: "aspartylglucosylaminidase activity" EXACT [EC:3.5.1.26] +synonym: "aspartylglycosylamine amidohydrolase activity" EXACT [EC:3.5.1.26] +synonym: "beta-aspartylglucosylamine amidohydrolase activity" EXACT [EC:3.5.1.26] +synonym: "glucosylamidase activity" RELATED [EC:3.5.1.26] +synonym: "glycosylasparaginase activity" EXACT [EC:3.5.1.26] +synonym: "N-aspartyl-beta-glucosaminidase activity" EXACT [EC:3.5.1.26] +synonym: "N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.26] +xref: EC:3.5.1.26 +xref: KEGG_REACTION:R03421 +xref: MetaCyc:3.5.1.26-RXN +xref: RHEA:11544 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0003949 +name: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide." [EC:5.3.1.16, RHEA:15469] +synonym: "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity" EXACT [EC:5.3.1.16] +synonym: "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity" EXACT [EC:5.3.1.16] +synonym: "N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] +synonym: "N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] +synonym: "phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity" EXACT [EC:5.3.1.16] +synonym: "phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] +xref: EC:5.3.1.16 +xref: KEGG_REACTION:R04640 +xref: MetaCyc:PRIBFAICARPISOM-RXN +xref: RHEA:15469 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0003950 +name: NAD+ ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor." [EC:2.4.2.30] +synonym: "ADP-ribosyltransferase (polymerizing) activity" EXACT [EC:2.4.2.30] +synonym: "NAD ADP-ribosyltransferase activity" EXACT [] +synonym: "NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [EC:2.4.2.30] +synonym: "poly(adenosine diphosphate ribose) polymerase activity" EXACT [EC:2.4.2.30] +synonym: "poly(ADP-ribose) synthase activity" EXACT [EC:2.4.2.30] +synonym: "poly(ADP-ribose) synthetase activity" EXACT [EC:2.4.2.30] +synonym: "poly(ADP-ribose)polymerase activity" EXACT [EC:2.4.2.30] +xref: EC:2.4.2.30 +xref: MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-2187325 "PARP1 ADP-ribosylates SMAD3 and SMAD4" +xref: Reactome:R-HSA-3640858 "Tankyrase ADP-ribosylates AXIN" +xref: Reactome:R-HSA-5651723 "PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate" +xref: Reactome:R-HSA-5687653 "PARP1,PARP2 dimers bound to MMEJ sites autoPARylate" +xref: Reactome:R-HSA-5688276 "SIRT4 transfers ADPRib to GLUD" +xref: Reactome:R-HSA-8938073 "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)" +xref: Reactome:R-HSA-8948800 "TNKS and TNKS2 PARylate PTEN" +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0003951 +name: NAD+ kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+)." [EC:2.7.1.23, RHEA:18629] +synonym: "ATP:NAD+ 2'-phosphotransferase activity" EXACT [EC:2.7.1.23] +synonym: "DPN kinase activity" RELATED [EC:2.7.1.23] +synonym: "NAD kinase activity" EXACT [] +synonym: "NADK" RELATED [EC:2.7.1.23] +synonym: "nicotinamide adenine dinucleotide kinase (phosphorylating)" EXACT [EC:2.7.1.23] +synonym: "nicotinamide adenine dinucleotide kinase activity" EXACT [EC:2.7.1.23] +xref: EC:2.7.1.23 +xref: KEGG_REACTION:R00104 +xref: MetaCyc:NAD-KIN-RXN +xref: Reactome:R-HSA-197198 "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+" +xref: Reactome:R-HSA-8955030 "NADK2 dimer phosphorylates NAD+ to NADP+" +xref: RHEA:18629 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0003952 +name: NAD+ synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate." [EC:6.3.5.1] +synonym: "deamido-NAD+:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.1] +synonym: "desamidonicotinamide adenine dinucleotide amidotransferase activity" EXACT [EC:6.3.5.1] +synonym: "DPN synthetase activity" EXACT [EC:6.3.5.1] +synonym: "NAD synthase (glutamine-hydrolyzing) activity" EXACT [] +synonym: "NAD synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.1] +synonym: "NAD(+) synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.1] +synonym: "NAD+ synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.1] +synonym: "NAD+ synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.1] +synonym: "nicotinamide adenine dinucleotide synthetase (glutamine) activity" EXACT [EC:6.3.5.1] +xref: EC:6.3.5.1 +xref: MetaCyc:NAD-SYNTH-GLN-RXN +xref: Reactome:R-HSA-197271 "NADSYN1 hexamer amidates NAAD to NAD+" +xref: RHEA:24384 +xref: Wikipedia:NAD+_synthase_(glutamine-hydrolysing) +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0003953 +name: NAD+ nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose." [GOC:dph, GOC:pad, GOC:PARL, GOC:pde, PMID:11866528, PMID:7805847] +synonym: "NAD nucleosidase activity" EXACT [] +xref: Reactome:R-HSA-8870346 "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose" +xref: Reactome:R-HSA-8938076 "CD38 hydrolyses NAD+ to NAM and ADP-ribose" +xref: RHEA:16301 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0003954 +name: NADH dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor." [EC:1.6.99.3] +synonym: "beta-NADH dehydrogenase dinucleotide activity" EXACT [EC:1.6.99.3] +synonym: "cytochrome c reductase activity" RELATED [EC:1.6.99.3] +synonym: "diaphorase activity" BROAD [EC:1.6.99.3] +synonym: "dihydrocodehydrogenase I dehydrogenase activity" EXACT [EC:1.6.99.3] +synonym: "dihydronicotinamide adenine dinucleotide dehydrogenase activity" EXACT [EC:1.6.99.3] +synonym: "diphosphopyridine diaphorase activity" EXACT [EC:1.6.99.3] +synonym: "diphosphopyrinase activity" EXACT [EC:1.6.99.3] +synonym: "DPNH diaphorase activity" EXACT [EC:1.6.99.3] +synonym: "NADH diaphorase activity" EXACT [EC:1.6.99.3] +synonym: "NADH hydrogenase activity" EXACT [EC:1.6.99.3] +synonym: "NADH oxidoreductase activity" EXACT [EC:1.6.99.3] +synonym: "NADH-menadione oxidoreductase activity" NARROW [EC:1.6.99.3] +synonym: "NADH2 dehydrogenase activity" EXACT [EC:1.6.99.3] +synonym: "NADH:(acceptor) oxidoreductase activity" EXACT [EC:1.6.99.3] +synonym: "NADH:acceptor oxidoreductase activity" EXACT [EC:1.6.99.3] +synonym: "NADH:cytochrome c oxidoreductase activity" NARROW [EC:1.6.99.3] +synonym: "reduced diphosphopyridine nucleotide diaphorase activity" EXACT [EC:1.6.99.3] +synonym: "type 1 dehydrogenase activity" RELATED [EC:1.6.99.3] +synonym: "type I dehydrogenase activity" RELATED [EC:1.6.99.3] +xref: EC:1.6.99.3 +xref: MetaCyc:NADH-DEHYDROGENASE-RXN +xref: RHEA:11356 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0003955 +name: NAD(P)H dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone." [EC:1.6.5.2] +synonym: "azoreductase activity" BROAD [EC:1.6.5.2] +synonym: "dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity" EXACT [EC:1.6.5.2] +synonym: "diaphorase activity" BROAD [EC:1.6.5.2] +synonym: "DT-diaphorase activity" EXACT [EC:1.6.5.2] +synonym: "flavoprotein NAD(P)H-quinone reductase activity" EXACT [EC:1.6.5.2] +synonym: "menadione oxidoreductase activity" NARROW [EC:1.6.5.2] +synonym: "menadione reductase activity" NARROW [EC:1.6.5.2] +synonym: "NAD(P)H dehydrogenase activity" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H menadione reductase activity" BROAD [EC:1.6.5.2] +synonym: "NAD(P)H(2) dehydrogenase (quinone) activity" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H-quinone dehydrogenase activity" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H-quinone oxidoreductase activity" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H2 dehydrogenase (quinone)" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H: menadione oxidoreductase activity" BROAD [EC:1.6.5.2] +synonym: "NAD(P)H:(quinone-acceptor)oxidoreductase activity" EXACT [EC:1.6.5.2] +synonym: "NAD(P)H:quinone oxidoreductase activity" EXACT [EC:1.6.5.2] +synonym: "NADH-menadione reductase activity" NARROW [EC:1.6.5.2] +synonym: "Naphthoquinone reductase activity" NARROW [EC:1.6.5.2] +synonym: "naphthoquinone reductase activity" EXACT [EC:1.6.5.2] +synonym: "NQO1" RELATED [EC:1.6.5.2] +synonym: "p-benzoquinone reductase activity" NARROW [EC:1.6.5.2] +synonym: "phylloquinone reductase activity" NARROW [EC:1.6.5.2] +synonym: "QR1" RELATED [EC:1.6.5.2] +synonym: "quinone reductase activity" EXACT [EC:1.6.5.2] +synonym: "reduced NAD(P)H dehydrogenase activity" EXACT [EC:1.6.5.2] +synonym: "reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity" EXACT [EC:1.6.5.2] +synonym: "viologen accepting pyridine nucleotide oxidoreductase activity" NARROW [EC:1.6.5.2] +synonym: "vitamin K reductase activity" NARROW [EC:1.6.5.2] +synonym: "vitamin-K reductase activity" NARROW [EC:1.6.5.2] +xref: EC:1.6.5.2 +xref: MetaCyc:NQOR-RXN +xref: UM-BBD_reactionID:r0227 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0003956 +name: NAD(P)+-protein-arginine ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine." [EC:2.4.2.31] +synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.31] +synonym: "mono(ADP-ribosyl)transferase activity" BROAD [EC:2.4.2.31] +synonym: "mono(ADPribosyl)transferase activity" BROAD [EC:2.4.2.31] +synonym: "NAD(+):L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] +synonym: "NAD(P)(+)--arginine ADP-ribosyltransferase activity" EXACT [EC:2.4.2.31] +synonym: "NAD(P)+-arginine ADP-ribosyltransferase activity" EXACT [] +synonym: "NAD(P)+:L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] +synonym: "NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] +synonym: "NAD(P)-arginine ADP-ribosyltransferase activity" EXACT [] +synonym: "NAD+:L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] +synonym: "peptidyl-arginine ADP-ribosylation activity" EXACT [] +synonym: "protein-arginine ADP-ribosyltransferase activity" EXACT [] +xref: EC:2.4.2.31 +xref: MetaCyc:2.4.2.31-RXN +xref: Reactome:R-HSA-1972385 "ADP-Ribosylation of HNP-1" +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0003957 +name: NAD(P)+ transhydrogenase (B-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+." [EC:1.6.1.1, http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf, MetaCyc:PYRNUTRANSHYDROGEN-RXN] +synonym: "H+-thase" BROAD [EC:1.6.1.1] +synonym: "NAD transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "NAD(P) transhydrogenase (B-specific) activity" EXACT [] +synonym: "NADH transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "NADH-NADP-transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "NADPH-NAD oxidoreductase" BROAD [EC:1.6.1.1] +synonym: "NADPH-NAD transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "NADPH:NAD+ oxidoreductase (B-specific)" EXACT [EC:1.6.1.1] +synonym: "NADPH:NAD+ transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "nicotinamide adenine dinucleotide (phosphate) transhydrogenase" BROAD [EC:1.6.1.1] +synonym: "nicotinamide nucleotide transhydrogenase activity" BROAD [EC:1.6.1.1] +synonym: "non-energy-linked transhydrogenase activity" EXACT [EC:1.6.1.1] +synonym: "pyridine nucleotide transferase" BROAD [EC:1.6.1.1] +synonym: "pyridine nucleotide transhydrogenase activity" BROAD [EC:1.6.1.1] +xref: EC:1.6.1.1 +xref: MetaCyc:PYRNUTRANSHYDROGEN-RXN +is_a: GO:0008746 ! NAD(P)+ transhydrogenase activity +is_a: GO:0015078 ! proton transmembrane transporter activity + +[Term] +id: GO:0003958 +name: NADPH-hemoprotein reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein." [EC:1.6.2.4] +synonym: "aldehyde reductase (NADPH-dependent) activity" RELATED [EC:1.6.2.4] +synonym: "CPR activity" RELATED [EC:1.6.2.4] +synonym: "cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity" NARROW [EC:1.6.2.4] +synonym: "cytochrome P-450 reductase activity" EXACT [EC:1.6.2.4] +synonym: "cytochrome P450 reductase activity" NARROW [EC:1.6.2.4] +synonym: "dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "FAD-cytochrome c reductase activity" RELATED [EC:1.6.2.4] +synonym: "ferrihemoprotein P-450 reductase activity" RELATED [EC:1.6.2.4] +synonym: "NADP--cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADP--cytochrome reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--cytochrome c oxidoreductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--cytochrome P450 oxidoreductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--cytochrome P450 reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--ferricytochrome c oxidoreductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH--ferrihemoprotein reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH-cytochrome P-450 oxidoreductase activity" EXACT [EC:1.6.2.4] +synonym: "NADPH-cytochrome p-450 reductase activity" EXACT [EC:1.6.2.4] +synonym: "NADPH-dependent cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "NADPH-ferrihemoprotein reductase activity" EXACT [] +synonym: "NADPH:cytochrome c reductase activity" EXACT [] +synonym: "NADPH:cytochrome P450 reductase activity" EXACT [] +synonym: "NADPH:ferrihemoprotein oxidoreductase activity" EXACT [EC:1.6.2.4] +synonym: "NADPH:hemoprotein oxidoreductase activity" EXACT [EC:1.6.2.4] +synonym: "NADPH:P-450 reductase activity" EXACT [EC:1.6.2.4] +synonym: "NADPH:P450 reductase activity" NARROW [EC:1.6.2.4] +synonym: "POR" RELATED [EC:1.6.2.4] +synonym: "reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity" NARROW [EC:1.6.2.4] +synonym: "TPNH(2) cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "TPNH-cytochrome c reductase activity" NARROW [EC:1.6.2.4] +synonym: "TPNH2 cytochrome c reductase activity" EXACT [EC:1.6.2.4] +xref: EC:1.6.2.4 +xref: MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN +xref: Reactome:R-HSA-76494 "POR reduces CYP450:Fe3+ to CYP450:Fe2+" +is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor + +[Term] +id: GO:0003959 +name: NADPH dehydrogenase activity +namespace: molecular_function +alt_id: GO:0008468 +alt_id: GO:0016660 +def: "Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor." [EC:1.6.99.1] +synonym: "dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH diaphorase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH-dehydrogenase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH2 diaphorase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH2-dehydrogenase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH:(acceptor) oxidoreductase activity" EXACT [EC:1.6.99.1] +synonym: "NADPH:acceptor oxidoreductase activity" EXACT [EC:1.6.99.1] +synonym: "old yellow enzyme" RELATED [EC:1.6.99.1] +synonym: "OYE" RELATED [EC:1.6.99.1] +synonym: "reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity" EXACT [EC:1.6.99.1] +synonym: "TPNH dehydrogenase activity" EXACT [EC:1.6.99.1] +synonym: "TPNH-diaphorase activity" EXACT [EC:1.6.99.1] +synonym: "triphosphopyridine diaphorase activity" EXACT [EC:1.6.99.1] +synonym: "triphosphopyridine nucleotide diaphorase activity" EXACT [EC:1.6.99.1] +xref: EC:1.6.99.1 +xref: MetaCyc:NADPH-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-9018867 "5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2" +xref: Reactome:R-HSA-9018901 "5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2" +xref: Reactome:R-HSA-9027625 "5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3" +xref: Reactome:R-HSA-9027631 "5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA" +xref: Reactome:R-HSA-9027632 "5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA" +xref: UM-BBD_enzymeID:e0523 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0003960 +name: NADPH:quinone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone." [EC:1.6.5.5] +synonym: "NADPH:quinone oxidoreductase activity" EXACT [EC:1.6.5.5] +synonym: "quinone oxidoreductase activity" BROAD [EC:1.6.5.5] +synonym: "zeta-crystallin activity" NARROW [EC:1.6.5.5] +xref: EC:1.6.5.5 +xref: MetaCyc:QOR-RXN +xref: Reactome:R-HSA-6799722 "TP53I3 oxidoreductase generates unstable semiquinones" +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0003961 +name: O-acetylhomoserine aminocarboxypropyltransferase activity +namespace: molecular_function +alt_id: GO:0019282 +def: "Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers." [EC:2.5.1.49] +comment: Note that this function was formerly EC:4.2.99.10. +synonym: "L-methionine anabolism, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] +synonym: "L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT [] +synonym: "L-methionine formation, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] +synonym: "L-methionine synthesis, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] +synonym: "O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity" EXACT [EC:2.5.1.49] +synonym: "O-acetyl-L-homoserine sulfhydrolase activity" EXACT [EC:2.5.1.49] +synonym: "O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.49] +synonym: "O-acetylhomoserine (thiol)-lyase activity" EXACT [] +synonym: "O-acetylhomoserine sulfhydrolase activity" EXACT [EC:2.5.1.49] +synonym: "OAH sulfhydrylase activity" EXACT [EC:2.5.1.49] +xref: EC:2.5.1.49 +xref: MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN +xref: RHEA:10048 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +relationship: part_of GO:0071266 ! 'de novo' L-methionine biosynthetic process + +[Term] +id: GO:0003962 +name: cystathionine gamma-synthase activity +namespace: molecular_function +alt_id: GO:0000505 +def: "Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate." [EC:2.5.1.48] +synonym: "CTT gamma synthase activity" EXACT [] +synonym: "cystathionine g-synthase activity" EXACT [] +synonym: "cystathionine gamma synthase activity" EXACT [] +synonym: "cystathionine synthase activity" EXACT [EC:2.5.1.48] +synonym: "cystathionine synthetase activity" EXACT [EC:2.5.1.48] +synonym: "homoserine O-transsuccinylase activity" BROAD [EC:2.5.1.48] +synonym: "homoserine transsuccinylase activity" BROAD [EC:2.5.1.48] +synonym: "O-succinyl-L-homoserine (thiol)-lyase activity" EXACT [] +synonym: "O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity" EXACT [EC:2.5.1.48] +synonym: "O-succinyl-L-homoserine succinate-lyase activity" EXACT [] +synonym: "O-succinylhomoserine (thiol)-lyase activity" EXACT [EC:2.5.1.48] +synonym: "O-succinylhomoserine synthase activity" EXACT [EC:2.5.1.48] +synonym: "O-succinylhomoserine synthetase activity" EXACT [EC:2.5.1.48] +synonym: "O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity" EXACT [EC:2.5.1.48] +xref: EC:2.5.1.48 +xref: MetaCyc:O-SUCCHOMOSERLYASE-RXN +xref: RHEA:20397 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0003963 +name: RNA-3'-phosphate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate." [EC:6.5.1.4] +synonym: "RNA 3'-terminal phosphate cyclase activity" EXACT [EC:6.5.1.4] +synonym: "RNA cyclase activity" EXACT [EC:6.5.1.4] +synonym: "RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)" EXACT [EC:6.5.1.4] +xref: EC:6.5.1.4 +xref: MetaCyc:RNA-3-PHOSPHATE-CYCLASE-RXN +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0003964 +name: RNA-directed DNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time." [EC:2.7.7.49] +synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.49] +synonym: "DNA nucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.49] +synonym: "reverse transcriptase activity" EXACT [EC:2.7.7.49] +synonym: "revertase activity" RELATED [EC:2.7.7.49] +synonym: "RNA revertase activity" EXACT [EC:2.7.7.49] +synonym: "RNA-dependent deoxyribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.49] +synonym: "RNA-dependent DNA polymerase activity" EXACT [EC:2.7.7.49] +synonym: "RNA-directed DNA polymerase, group II intron encoded" NARROW [] +synonym: "RNA-directed DNA polymerase, transposon encoded" NARROW [] +synonym: "RNA-instructed DNA polymerase activity" EXACT [EC:2.7.7.49] +synonym: "RT" RELATED [EC:2.7.7.49] +xref: EC:2.7.7.49 +xref: MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN +xref: Reactome:R-HSA-164504 "Synthesis of minus strand strong stop DNA (-sssDNA)" +xref: Reactome:R-HSA-164520 "Minus strand DNA synthesis resumes" +is_a: GO:0034061 ! DNA polymerase activity +relationship: part_of GO:0006278 ! RNA-dependent DNA biosynthetic process + +[Term] +id: GO:0003966 +name: obsolete RNA-directed DNA polymerase, transposon encoded +namespace: molecular_function +def: "OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo." [EC:2.7.7.49] +comment: This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'. +synonym: "RNA-directed DNA polymerase, transposon encoded" EXACT [] +is_obsolete: true +replaced_by: GO:0003964 + +[Term] +id: GO:0003967 +name: obsolete RNA-directed DNA polymerase, group II intron encoded +namespace: molecular_function +def: "OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo." [EC:2.7.7.49] +comment: This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'. +synonym: "RNA-directed DNA polymerase, group II intron encoded" EXACT [] +is_obsolete: true +replaced_by: GO:0003964 + +[Term] +id: GO:0003968 +name: RNA-directed 5'-3' RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time." [EC:2.7.7.48, GOC:mah, GOC:pf] +synonym: "3D polymerase activity" EXACT [EC:2.7.7.48] +synonym: "nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [EC:2.7.7.48] +synonym: "PB1 proteins" RELATED [EC:2.7.7.48] +synonym: "PB2 proteins" RELATED [EC:2.7.7.48] +synonym: "phage f2 replicase" NARROW [EC:2.7.7.48] +synonym: "polymerase L" RELATED [EC:2.7.7.48] +synonym: "Q-beta replicase activity" EXACT [EC:2.7.7.48] +synonym: "RDRP" RELATED [EC:2.7.7.48] +synonym: "ribonucleic acid replicase activity" EXACT [EC:2.7.7.48] +synonym: "ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.48] +synonym: "ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [EC:2.7.7.48] +synonym: "ribonucleic replicase activity" EXACT [EC:2.7.7.48] +synonym: "ribonucleic synthetase activity" RELATED [EC:2.7.7.48] +synonym: "RNA nucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.48] +synonym: "RNA replicase activity" EXACT [EC:2.7.7.48] +synonym: "RNA synthetase activity" RELATED [EC:2.7.7.48] +synonym: "RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.48] +synonym: "RNA-dependent RNA polymerase activity" EXACT [EC:2.7.7.48] +synonym: "RNA-dependent RNA replicase activity" EXACT [EC:2.7.7.48] +synonym: "RNA-directed RNA polymerase activity" BROAD [] +synonym: "transcriptase" BROAD [EC:2.7.7.48] +xref: EC:2.7.7.48 +xref: MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN +xref: Reactome:R-HSA-168280 "Priming and Initiation of Transcription" +xref: Reactome:R-HSA-168301 "Elongation, Polyadenylation and Termination" +xref: Reactome:R-HSA-192624 "cRNA Extension" +xref: Reactome:R-HSA-192832 "Initiation of cRNA Synthesis" +xref: Reactome:R-HSA-192851 "vRNA Extension" +xref: Reactome:R-HSA-192916 "Initiation of vRNA Synthesis" +is_a: GO:0034062 ! 5'-3' RNA polymerase activity +relationship: part_of GO:0001172 ! transcription, RNA-templated + +[Term] +id: GO:0003969 +name: obsolete RNA editase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a biological process. +synonym: "RNA editase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0003972 +name: RNA ligase (ATP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m)." [EC:6.5.1.3] +synonym: "poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)" EXACT [EC:6.5.1.3] +synonym: "polyribonucleotide ligase activity" EXACT [EC:6.5.1.3] +synonym: "polyribonucleotide synthase (ATP) activity" EXACT [EC:6.5.1.3] +synonym: "ribonucleic ligase activity" BROAD [EC:6.5.1.3] +xref: EC:6.5.1.3 +xref: MetaCyc:RNA-LIGASE-ATP-RXN +xref: Reactome:R-HSA-5696816 "tRNA ligase complex ligates tRNA exons" +is_a: GO:0008452 ! RNA ligase activity + +[Term] +id: GO:0003973 +name: (S)-2-hydroxy-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide." [EC:1.1.3.15] +synonym: "(S)-2-hydroxy-acid:oxygen 2-oxidoreductase" EXACT [EC:1.1.3.15] +synonym: "hydroxy-acid oxidase A activity" NARROW [EC:1.1.3.15] +synonym: "hydroxy-acid oxidase B activity" NARROW [EC:1.1.3.15] +synonym: "hydroxyacid oxidase A" RELATED [EC:1.1.3.15] +synonym: "L-2-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "L-alpha-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "oxidase, L-2-hydroxy acid" EXACT [EC:1.1.3.15] +xref: EC:1.1.3.15 +xref: MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0003974 +name: UDP-N-acetylglucosamine 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine." [EC:5.1.3.7] +synonym: "UDP acetylglucosamine epimerase activity" EXACT [EC:5.1.3.7] +synonym: "UDP-GlcNAc 4-epimerase activity" EXACT [EC:5.1.3.7] +synonym: "UDP-N-acetyl-D-glucosamine 4-epimerase activity" EXACT [EC:5.1.3.7] +synonym: "uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity" EXACT [EC:5.1.3.7] +synonym: "uridine diphosphate N-acetylglucosamine-4-epimerase activity" EXACT [EC:5.1.3.7] +synonym: "uridine diphosphoacetylglucosamine epimerase activity" EXACT [EC:5.1.3.7] +xref: EC:5.1.3.7 +xref: MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN +xref: RHEA:20517 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0003975 +name: UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol." [EC:2.7.8.15] +synonym: "chitobiosylpyrophosphoryldolichol synthase activity" EXACT [EC:2.7.8.15] +synonym: "dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] +synonym: "GlcNAc-1-P transferase activity" EXACT [EC:2.7.8.15] +synonym: "N-acetylglucosamine-1-phosphate transferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity" EXACT [EC:2.7.8.15] +synonym: "UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity" EXACT [] +synonym: "uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] +xref: EC:2.7.8.15 +xref: MetaCyc:2.7.8.15-RXN +xref: Reactome:R-HSA-446191 "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate" +xref: Reactome:R-HSA-4549334 "Defective DPAGT1 does not transfer GlcNAc to DOLP" +xref: RHEA:13289 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0003976 +name: UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose." [EC:2.7.8.17] +synonym: "lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "N-acetylglucosaminyl phosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "N-acetylglucosaminylphosphotransferase activity" RELATED [EC:2.7.8.17] +synonym: "UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity" EXACT [EC:2.7.8.17] +synonym: "UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] +xref: EC:2.7.8.17 +xref: MetaCyc:2.7.8.17-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0003977 +name: UDP-N-acetylglucosamine diphosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine." [EC:2.7.7.23, RHEA:13509] +synonym: "acetylglucosamine 1-phosphate uridylyltransferase" BROAD [EC:2.7.7.23] +synonym: "GlmU uridylyltransferase activity" EXACT [EC:2.7.7.23] +synonym: "N-acetylglucosamine-1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.23] +synonym: "UDP-acetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] +synonym: "UDP-GlcNAc pyrophosphorylase activity" EXACT [EC:2.7.7.23] +synonym: "UDP-N-acetylglucosamine pyrophosphorylase activity" EXACT [] +synonym: "uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] +synonym: "uridine diphosphoacetylglucosamine phosphorylase activity" EXACT [EC:2.7.7.23] +synonym: "uridine diphosphoacetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] +synonym: "UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.23] +synonym: "UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.23] +xref: EC:2.7.7.23 +xref: KEGG_REACTION:R00416 +xref: MetaCyc:NAG1P-URIDYLTRANS-RXN +xref: Reactome:R-HSA-446204 "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine" +xref: RHEA:13509 +is_a: GO:0070569 ! uridylyltransferase activity + +[Term] +id: GO:0003978 +name: UDP-glucose 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose = UDP-galactose." [EC:5.1.3.2] +synonym: "4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "galactowaldenase activity" RELATED [EC:5.1.3.2] +synonym: "UDP-D-galactose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "UDP-galactose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "UDP-glucose epimerase activity" EXACT [EC:5.1.3.2] +synonym: "UDPG-4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "UDPgalactose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "UDPglucose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "uridine diphosphate galactose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "uridine diphosphate glucose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "uridine diphospho-galactose-4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "uridine diphosphoglucose 4-epimerase activity" EXACT [EC:5.1.3.2] +synonym: "uridine diphosphoglucose epimerase activity" EXACT [EC:5.1.3.2] +xref: EC:5.1.3.2 +xref: MetaCyc:UDPGLUCEPIM-RXN +xref: Reactome:R-HSA-5610036 "Defective GALE does not epimerise UDP-Gal to UDP-Glc" +xref: Reactome:R-HSA-70369 "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc" +xref: RHEA:22168 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0003979 +name: UDP-glucose 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate." [EC:1.1.1.22, RHEA:23596] +xref: EC:1.1.1.22 +xref: KEGG_REACTION:R00286 +xref: MetaCyc:UGD-RXN +xref: Reactome:R-HSA-173597 "UDP-glucose is oxidised to UDP-glucuronate" +xref: RHEA:23596 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0003980 +name: UDP-glucose:glycoprotein glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins." [GOC:al, PMID:10764828] +synonym: "UGGT activity" EXACT [] +xref: Reactome:R-HSA-548884 "UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b" +is_a: GO:0035251 ! UDP-glucosyltransferase activity +relationship: part_of GO:0097359 ! UDP-glucosylation + +[Term] +id: GO:0003983 +name: UTP:glucose-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose." [EC:2.7.7.9, RHEA:19889] +synonym: "glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] +synonym: "UDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "UDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "UDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "UDPG phosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "UDPG pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "uridine 5'-diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "uridine diphosphate-D-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "uridine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "uridine-diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] +synonym: "UTP-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] +synonym: "UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] +xref: EC:2.7.7.9 +xref: KEGG_REACTION:R00289 +xref: MetaCyc:GLUC1PURIDYLTRANS-RXN +xref: Reactome:R-HSA-70286 "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose" +xref: RHEA:19889 +is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity + +[Term] +id: GO:0003984 +name: acetolactate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2." [EC:2.2.1.6, RHEA:25249] +comment: Note that this function was formerly EC:4.1.3.18. +synonym: "acetohydroxy acid synthetase activity" EXACT [EC:2.2.1.6] +synonym: "acetohydroxyacid synthase activity" EXACT [EC:2.2.1.6] +synonym: "acetolactate pyruvate-lyase (carboxylating) activity" EXACT [EC:2.2.1.6] +synonym: "acetolactic synthetase activity" EXACT [EC:2.2.1.6] +synonym: "alpha-acetohydroxy acid synthetase activity" EXACT [EC:2.2.1.6] +synonym: "alpha-acetohydroxyacid synthase activity" EXACT [EC:2.2.1.6] +synonym: "alpha-acetolactate synthase activity" EXACT [EC:2.2.1.6] +synonym: "alpha-acetolactate synthetase activity" EXACT [EC:2.2.1.6] +synonym: "pyruvate:pyruvate acetaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.6] +xref: EC:2.2.1.6 +xref: MetaCyc:ACETOLACTSYN-RXN +xref: RHEA:25249 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0003985 +name: acetyl-CoA C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA." [EC:2.3.1.9] +synonym: "2-methylacetoacetyl-CoA thiolase" BROAD [EC:2.3.1.9] +synonym: "3-oxothiolase activity" EXACT [EC:2.3.1.9] +synonym: "acetoacetyl-CoA thiolase activity" EXACT [EC:2.3.1.9] +synonym: "acetyl coenzyme A thiolase activity" EXACT [EC:2.3.1.9] +synonym: "acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.9] +synonym: "acetyl-CoA:acetyl-CoA C-acetyltransferase activity" EXACT [EC:2.3.1.9] +synonym: "acetyl-CoA:N-acetyltransferase activity" EXACT [EC:2.3.1.9] +synonym: "beta-acetoacetyl coenzyme A thiolase activity" EXACT [EC:2.3.1.9] +synonym: "thiolase II" RELATED [EC:2.3.1.9] +xref: EC:2.3.1.9 +xref: MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN +xref: Reactome:R-HSA-70844 "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA" +xref: Reactome:R-HSA-73916 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA" +xref: Reactome:R-HSA-74181 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA" +xref: Reactome:R-HSA-8848215 "ACAT2 condenses 2 Ac-CoA to form ACA-CoA" +xref: RHEA:21036 +xref: UM-BBD_enzymeID:e0144 +is_a: GO:0003988 ! acetyl-CoA C-acyltransferase activity +is_a: GO:0016453 ! C-acetyltransferase activity + +[Term] +id: GO:0003986 +name: acetyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+)." [EC:3.1.2.1, RHEA:20289] +synonym: "acetyl coenzyme A acylase activity" EXACT [EC:3.1.2.1] +synonym: "acetyl coenzyme A deacylase activity" EXACT [EC:3.1.2.1] +synonym: "acetyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.1] +synonym: "acetyl-CoA acylase activity" EXACT [EC:3.1.2.1] +synonym: "acetyl-CoA deacylase activity" EXACT [EC:3.1.2.1] +synonym: "acetyl-CoA thiol esterase activity" EXACT [EC:3.1.2.1] +xref: EC:3.1.2.1 +xref: KEGG_REACTION:R00227 +xref: MetaCyc:ACETYL-COA-HYDROLASE-RXN +xref: Reactome:R-HSA-2066779 "Conversion of DHA-CoA to docosahexaenoic acid (DHA)" +xref: Reactome:R-HSA-390304 "acetyl-CoA + H2O => acetate + CoASH" +xref: RHEA:20289 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0003987 +name: acetate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA." [EC:6.2.1.1] +synonym: "acetate thiokinase activity" BROAD [EC:6.2.1.1] +synonym: "acetate to acetyl-CoA" RELATED [] +synonym: "acetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.1] +synonym: "acetic thiokinase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl activating enzyme" RELATED [EC:6.2.1.1] +synonym: "acetyl CoA ligase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl CoA synthase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl coenzyme A synthetase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl-activating enzyme activity" EXACT [EC:6.2.1.1] +synonym: "acetyl-CoA synthase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl-CoA synthetase activity" EXACT [EC:6.2.1.1] +synonym: "acetyl-coenzyme A synthase activity" EXACT [EC:6.2.1.1] +synonym: "ACS" RELATED [EC:6.2.1.1] +synonym: "acyl-activating enzyme activity" BROAD [EC:6.2.1.1] +synonym: "short chain fatty acyl-CoA synthetase activity" EXACT [EC:6.2.1.1] +synonym: "short-chain acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.1] +xref: EC:6.2.1.1 +xref: MetaCyc:ACETATE--COA-LIGASE-RXN +xref: Reactome:R-HSA-449911 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]" +xref: Reactome:R-HSA-71735 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]" +xref: Reactome:R-HSA-8875071 "ACSS3 ligates CoA to CH3COO-" +xref: RHEA:23176 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0003988 +name: acetyl-CoA C-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA." [EC:2.3.1.16] +synonym: "2-keto-acyl thiolase activity" EXACT [] +synonym: "2-methylacetoacetyl-CoA thiolase" BROAD [EC:2.3.1.16] +synonym: "3-ketoacyl CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "3-ketoacyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "3-ketoacyl thiolase activity" EXACT [EC:2.3.1.16] +synonym: "3-ketoacyl-CoA thiolase activity" EXACT [] +synonym: "3-ketothiolase activity" EXACT [EC:2.3.1.16] +synonym: "3-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "3-oxoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "6-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "acetoacetyl-CoA beta-ketothiolase activity" EXACT [EC:2.3.1.16] +synonym: "acetyl-CoA acyltransferase activity" EXACT [EC:2.3.1.16] +synonym: "acyl-CoA:acetyl-CoA C-acyltransferase activity" EXACT [EC:2.3.1.16] +synonym: "beta-ketoacyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "beta-ketoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "beta-ketoadipyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "beta-ketoadipyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "beta-ketothiolase activity" EXACT [EC:2.3.1.16] +synonym: "KAT" RELATED [EC:2.3.1.16] +synonym: "ketoacyl-CoA acyltransferase activity" EXACT [EC:2.3.1.16] +synonym: "ketoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "long-chain 3-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "oxoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] +synonym: "pro-3-ketoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] +synonym: "thiolase I" RELATED [EC:2.3.1.16] +xref: EC:2.3.1.16 +xref: MetaCyc:KETOACYLCOATHIOL-RXN +xref: Reactome:R-HSA-390250 "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA" +xref: Reactome:R-HSA-77271 "3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA" +xref: Reactome:R-HSA-77304 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA" +xref: Reactome:R-HSA-77309 "3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA" +xref: Reactome:R-HSA-77321 "3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA" +xref: Reactome:R-HSA-77329 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA" +xref: Reactome:R-HSA-77340 "3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA" +xref: Reactome:R-HSA-8874745 "ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH" +xref: RHEA:21564 +xref: UM-BBD_reactionID:r1051 +is_a: GO:0016408 ! C-acyltransferase activity + +[Term] +id: GO:0003989 +name: acetyl-CoA carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA." [EC:6.4.1.2] +synonym: "acetyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.2] +synonym: "acetyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.2] +xref: EC:6.4.1.2 +xref: MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN +xref: Reactome:R-HSA-200555 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate" +xref: Reactome:R-HSA-75851 "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA" +xref: Reactome:R-HSA-8876889 "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA" +xref: RHEA:11308 +is_a: GO:0016421 ! CoA carboxylase activity + +[Term] +id: GO:0003990 +name: acetylcholinesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetylcholine + H2O = choline + acetate." [EC:3.1.1.7] +subset: goslim_chembl +synonym: "AcCholE" RELATED [EC:3.1.1.7] +synonym: "acetyl.beta-methylcholinesterase activity" EXACT [EC:3.1.1.7] +synonym: "acetylcholine acetylhydrolase activity" EXACT [EC:3.1.1.7] +synonym: "acetylcholine hydrolase activity" EXACT [EC:3.1.1.7] +synonym: "acetylthiocholinesterase activity" EXACT [EC:3.1.1.7] +synonym: "choline esterase I activity" EXACT [EC:3.1.1.7] +synonym: "true cholinesterase activity" EXACT [EC:3.1.1.7] +xref: EC:3.1.1.7 +xref: MetaCyc:ACETYLCHOLINESTERASE-RXN +xref: Reactome:R-HSA-372519 "AcCho is hydrolyzed to Cho and acetate by ACHE" +xref: RHEA:17561 +is_a: GO:0004104 ! cholinesterase activity + +[Term] +id: GO:0003991 +name: acetylglutamate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate." [EC:2.7.2.8] +synonym: "acetylglutamate phosphokinase activity" EXACT [EC:2.7.2.8] +synonym: "ATP:N-acetyl-L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.8] +synonym: "N-acetylglutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.8] +synonym: "N-acetylglutamate kinase activity" EXACT [EC:2.7.2.8] +synonym: "N-acetylglutamate phosphokinase activity" EXACT [EC:2.7.2.8] +synonym: "N-acetylglutamic 5-phosphotransferase activity" EXACT [EC:2.7.2.8] +xref: EC:2.7.2.8 +xref: MetaCyc:ACETYLGLUTKIN-RXN +xref: RHEA:14629 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0003992 +name: N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity +namespace: molecular_function +alt_id: GO:0047318 +def: "Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate." [EC:2.6.1.11, RHEA:18049] +synonym: "2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [EC:2.6.1.11] +synonym: "acetylornithine 5-aminotransferase activity" EXACT [EC:2.6.1.11] +synonym: "acetylornithine aminotransferase activity" BROAD [] +synonym: "acetylornithine delta-transaminase activity" EXACT [EC:2.6.1.11] +synonym: "acetylornithine transaminase activity" BROAD [EC:2.6.1.11] +synonym: "ACOAT activity" EXACT [EC:2.6.1.11] +synonym: "N(2)-acetylornithine 5-transaminase activity" EXACT [EC:2.6.1.11] +synonym: "N-acetylornithine aminotransferase activity" EXACT [EC:2.6.1.11] +synonym: "N-acetylornithine-delta-transaminase activity" EXACT [EC:2.6.1.11] +synonym: "N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.11] +synonym: "N2-acetylornithine 5-aminotransferase activity" EXACT [] +synonym: "N2-acetylornithine 5-transaminase activity" EXACT [EC:2.6.1.11] +synonym: "succinylornithine aminotransferase activity" BROAD [EC:2.6.1.11] +xref: EC:2.6.1.11 +xref: KEGG_REACTION:R02283 +xref: MetaCyc:ACETYLORNTRANSAM-RXN +xref: RHEA:18049 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0003993 +name: acid phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum." [EC:3.1.3.2] +synonym: "acid monophosphatase activity" EXACT [EC:3.1.3.2] +synonym: "acid nucleoside diphosphate phosphatase activity" EXACT [EC:3.1.3.2] +synonym: "acid phosphohydrolase activity" EXACT [EC:3.1.3.2] +synonym: "acid phosphomonoester hydrolase activity" EXACT [EC:3.1.3.2] +synonym: "acid phosphomonoesterase activity" EXACT [EC:3.1.3.2] +synonym: "glycerophosphatase activity" BROAD [EC:3.1.3.2] +synonym: "orthophosphoric-monoester phosphohydrolase (acid optimum)" EXACT [EC:3.1.3.2] +synonym: "phosphate-monoester phosphohydrolase (acid optimum)" EXACT [EC:3.1.3.2] +synonym: "phosphomonoesterase activity" BROAD [EC:3.1.3.2] +synonym: "uteroferrin" RELATED [EC:3.1.3.2] +xref: EC:3.1.3.2 +xref: MetaCyc:ACID-PHOSPHATASE-RXN +xref: Reactome:R-HSA-196950 "2xTRAP hydrolyzes FMN to RIB" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0003994 +name: aconitate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate." [EC:4.2.1.3, GOC:pde, GOC:vw] +comment: This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'. +synonym: "aconitase activity" EXACT [] +synonym: "cis-aconitase activity" EXACT [EC:4.2.1.3] +synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.3] +synonym: "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [EC:4.2.1.3] +synonym: "citrate(isocitrate) hydro-lyase activity" EXACT [EC:4.2.1.3] +xref: EC:4.2.1.3 +xref: Reactome:R-HSA-450975 "isocitrate <=> citrate" +xref: Reactome:R-HSA-5690911 "ACO1:4Fe-4S isomerises CIT to ISCIT" +xref: Reactome:R-HSA-70971 "citrate <=> isocitrate" +xref: RHEA:10336 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0003995 +name: acyl-CoA dehydrogenase activity +namespace: molecular_function +alt_id: GO:0019109 +def: "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor." [EC:1.3.99.3] +synonym: "acyl CoA dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "acyl dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "acyl-CoA reductase activity" EXACT [GOC:mah] +synonym: "acyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.99.3] +synonym: "acyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.99.3] +synonym: "fatty acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "fatty-acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "general acyl CoA dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "long-chain acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "long-chain acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.3] +synonym: "medium-chain acyl-CoA dehydrogenase activity" NARROW [EC:1.3.99.3] +synonym: "medium-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] +xref: EC:1.3.99.3 +xref: MetaCyc:ACYLCOADEHYDROG-RXN +xref: MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN +xref: Reactome:R-HSA-109341 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA" +xref: Reactome:R-HSA-5695980 "ACAD10 dehydrogenates S-2MPDA-CoA" +xref: Reactome:R-HSA-5695989 "ACAD11 dehydrogenates BH-CoA" +xref: Reactome:R-HSA-70800 "alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2" +xref: Reactome:R-HSA-70859 "isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2" +xref: Reactome:R-HSA-77263 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2" +xref: Reactome:R-HSA-77274 "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2" +xref: Reactome:R-HSA-77299 "palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2" +xref: Reactome:R-HSA-77319 "Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2" +xref: Reactome:R-HSA-77327 "Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2" +xref: Reactome:R-HSA-77338 "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2" +xref: Reactome:R-HSA-77345 "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2" +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0003996 +name: acyl-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain carboxylic acids have chain lengths of C13 to C22." [EC:6.2.1.3, GOC:mah] +xref: EC:6.2.1.3 +xref: Reactome:R-HSA-5696004 "ACSF2 ligates CoA-SH to MCFA" +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0003997 +name: acyl-CoA oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide." [EC:1.3.3.6] +synonym: "acyl coenzyme A oxidase activity" EXACT [EC:1.3.3.6] +synonym: "acyl-CoA:oxygen 2-oxidoreductase activity" EXACT [EC:1.3.3.6] +synonym: "fatty acyl-CoA oxidase activity" EXACT [EC:1.3.3.6] +synonym: "fatty acyl-coenzyme A oxidase activity" EXACT [EC:1.3.3.6] +xref: EC:1.3.3.6 +xref: MetaCyc:ACYL-COA-OXIDASE-RXN +xref: Reactome:R-HSA-192335 "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)" +xref: Reactome:R-HSA-193369 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA" +xref: Reactome:R-HSA-2066787 "Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA" +xref: Reactome:R-HSA-390256 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2" +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0003998 +name: acylphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate." [EC:3.6.1.7] +synonym: "1,3-diphosphoglycerate phosphatase activity" EXACT [EC:3.6.1.7] +synonym: "acetic phosphatase activity" EXACT [EC:3.6.1.7] +synonym: "acetylphosphatase activity" EXACT [EC:3.6.1.7] +synonym: "acylphosphate phosphohydrolase activity" EXACT [EC:3.6.1.7] +synonym: "GP 1-3" RELATED [EC:3.6.1.7] +synonym: "Ho 1-3" RELATED [EC:3.6.1.7] +xref: EC:3.6.1.7 +xref: MetaCyc:ACYLPHOSPHATASE-RXN +xref: RHEA:14965 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0003999 +name: adenine phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.7] +synonym: "adenine phosphoribosylpyrophosphate transferase activity" EXACT [EC:2.4.2.7] +synonym: "adenosine phosphoribosyltransferase activity" EXACT [EC:2.4.2.7] +synonym: "adenylate pyrophosphorylase activity" EXACT [EC:2.4.2.7] +synonym: "adenylic pyrophosphorylase activity" EXACT [EC:2.4.2.7] +synonym: "AMP diphosphorylase activity" EXACT [EC:2.4.2.7] +synonym: "AMP pyrophosphorylase activity" EXACT [EC:2.4.2.7] +synonym: "AMP-pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.7] +synonym: "AMP:diphosphate phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.7] +synonym: "APRT activity" EXACT [EC:2.4.2.7] +synonym: "transphosphoribosidase activity" RELATED [EC:2.4.2.7] +xref: EC:2.4.2.7 +xref: MetaCyc:ADENPRIBOSYLTRAN-RXN +xref: Reactome:R-HSA-74213 "Adenine + PRPP => AMP + PPi" +xref: RHEA:16609 +is_a: GO:0106130 ! purine phosphoribosyltransferase activity + +[Term] +id: GO:0004000 +name: adenosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3." [EC:3.5.4.4] +synonym: "adenosine aminohydrolase activity" EXACT [EC:3.5.4.4] +synonym: "adenosine deaminase reaction" EXACT [] +xref: EC:3.5.4.4 +xref: MetaCyc:ADENODEAMIN-RXN +xref: Reactome:R-HSA-2161187 "N6-methyl-AMP + H2O => IMP + methylamine" +xref: Reactome:R-HSA-2161195 "abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine" +xref: Reactome:R-HSA-5693346 "CECRI deaminates Ade-Rib to Ino" +xref: Reactome:R-HSA-74241 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)" +xref: RHEA:24408 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0004001 +name: adenosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + adenosine = ADP + AMP." [EC:2.7.1.20, PMID:11223943] +synonym: "adenosine 5-phosphotransferase activity" EXACT [] +synonym: "adenosine kinase (phosphorylating)" EXACT [EC:2.7.1.20] +synonym: "ATP:adenosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.20] +xref: EC:2.7.1.20 +xref: MetaCyc:ADENOSINE-KINASE-RXN +xref: Reactome:R-HSA-109624 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)" +xref: RHEA:20824 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019206 ! nucleoside kinase activity +relationship: part_of GO:0006167 ! AMP biosynthetic process + +[Term] +id: GO:0004005 +name: obsolete plasma membrane cation-transporting ATPase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "plasma membrane cation-transporting ATPase" EXACT [] +is_obsolete: true +consider: GO:0005886 +consider: GO:0019829 + +[Term] +id: GO:0004007 +name: obsolete heavy metal-exporting ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate." [GOC:ai] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "heavy metal-exporting ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0046873 + +[Term] +id: GO:0004009 +name: obsolete ATP-binding cassette (ABC) transporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. +synonym: "ATP-binding cassette (ABC) transporter activity" EXACT [] +is_obsolete: true +consider: GO:0042626 +consider: GO:0043190 + +[Term] +id: GO:0004013 +name: adenosylhomocysteinase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine." [EC:3.3.1.1] +subset: goslim_chembl +synonym: "adenosylhomocysteine hydrolase activity" EXACT [EC:3.3.1.1] +synonym: "AdoHcyase activity" EXACT [EC:3.3.1.1] +synonym: "S-adenosyl-L-homocysteine hydrolase activity" EXACT [EC:3.3.1.1] +synonym: "S-adenosylhomocysteinase activity" EXACT [EC:3.3.1.1] +synonym: "S-adenosylhomocysteine hydrolase activity" BROAD [EC:3.3.1.1] +synonym: "S-adenosylhomocysteine synthase activity" EXACT [EC:3.3.1.1] +synonym: "SAHase activity" EXACT [EC:3.3.1.1] +xref: EC:3.3.1.1 +xref: MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN +xref: Reactome:R-HSA-174401 "AHCY:NAD+ tetramer hydrolyses AdoHcy" +xref: Reactome:R-HSA-5579084 "Defective AHCY does not hydrolyse AdoHcy" +xref: RHEA:21708 +is_a: GO:0016802 ! trialkylsulfonium hydrolase activity + +[Term] +id: GO:0004014 +name: adenosylmethionine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2)." [EC:4.1.1.50, RHEA:15981] +synonym: "adenosyl methionine decarboxylase activity" EXACT [] +synonym: "S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]" RELATED [EC:4.1.1.50] +synonym: "S-adenosyl-L-methionine carboxy-lyase activity" EXACT [EC:4.1.1.50] +synonym: "S-adenosyl-L-methionine decarboxylase activity" EXACT [EC:4.1.1.50] +synonym: "S-adenosylmethionine decarboxylase activity" EXACT [EC:4.1.1.50] +xref: EC:4.1.1.50 +xref: KEGG_REACTION:R00178 +xref: MetaCyc:SAMDECARB-RXN +xref: Reactome:R-HSA-351222 "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2" +xref: RHEA:15981 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004015 +name: adenosylmethionine-8-amino-7-oxononanoate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate." [EC:2.6.1.62, RHEA:16861] +synonym: "7,8-diamino-pelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "7,8-diaminonanoate transaminase activity" EXACT [EC:2.6.1.62] +synonym: "7,8-diaminononanoate aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "7,8-diaminononanoate transaminase activity" EXACT [EC:2.6.1.62] +synonym: "7,8-diaminopelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "7-keto-8-aminopelargonic acid" RELATED [EC:2.6.1.62] +synonym: "7-keto-8-aminopelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "adenosyl methionine-8-amino-7-oxononanoate transaminase activity" EXACT [] +synonym: "adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity" EXACT [] +synonym: "DAPA aminotransferase activity" EXACT [EC:2.6.1.62] +synonym: "DAPA transaminase activity" EXACT [EC:2.6.1.62] +synonym: "diaminopelargonate synthase activity" EXACT [EC:2.6.1.62] +synonym: "S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity" EXACT [EC:2.6.1.62] +xref: EC:2.6.1.62 +xref: KEGG_REACTION:R03231 +xref: MetaCyc:DAPASYN-RXN +xref: RHEA:16861 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004016 +name: adenylate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate." [EC:4.6.1.1] +synonym: "3',5'-cyclic AMP synthetase activity" EXACT [EC:4.6.1.1] +synonym: "adenyl cyclase activity" EXACT [EC:4.6.1.1] +synonym: "adenylyl cyclase activity" EXACT [] +synonym: "adenylylcyclase activity" EXACT [EC:4.6.1.1] +synonym: "ATP diphosphate-lyase (cyclizing) activity" EXACT [EC:4.6.1.1] +synonym: "ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity" EXACT [EC:4.6.1.1] +synonym: "ATP pyrophosphate-lyase activity" EXACT [EC:4.6.1.1] +synonym: "cAMP generating peptide activity" RELATED [] +xref: EC:4.6.1.1 +xref: MetaCyc:ADENYLATECYC-RXN +xref: Reactome:R-HSA-164377 "Activated Adenylate cyclase catalyses cAMP synthesis" +xref: Reactome:R-HSA-170676 "Adenylate cyclase converts ATP into cyclic AMP" +xref: Reactome:R-HSA-381607 "Activated Adenylyl cyclase synthesizes cyclic AMP" +xref: Reactome:R-HSA-392129 "Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate" +xref: Reactome:R-HSA-5211224 "Anthrax EF catalyzes the conversion of ATP to cAMP" +xref: Reactome:R-HSA-5610727 "GPR161 promotes cAMP production in a G alpha(s)-dependent manner" +xref: RHEA:15389 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016849 ! phosphorus-oxygen lyase activity + +[Term] +id: GO:0004017 +name: adenylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + AMP = 2 ADP." [EC:2.7.4.3] +synonym: "5'-AMP-kinase activity" EXACT [EC:2.7.4.3] +synonym: "adenylic kinase activity" EXACT [EC:2.7.4.3] +synonym: "adenylokinase activity" EXACT [EC:2.7.4.3] +synonym: "ATP:AMP phosphotransferase activity" EXACT [EC:2.7.4.3] +synonym: "myokinase activity" NARROW [EC:2.7.4.3] +xref: EC:2.7.4.3 +xref: MetaCyc:ADENYL-KIN-RXN +xref: Reactome:R-HSA-110141 "(d)ADP + ADP <=> (d)AMP + ATP (AK1)" +xref: Reactome:R-HSA-110144 "ADP + ADP <=> AMP + ATP [AK2]" +xref: Reactome:R-HSA-110145 "AMP + ATP <=> ADP + ADP [AK2]" +xref: Reactome:R-HSA-74220 "(d)AMP + ATP <=> (d)ADP + ADP (AK1)" +xref: RHEA:12973 +is_a: GO:0050145 ! nucleoside monophosphate kinase activity + +[Term] +id: GO:0004018 +name: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP." [EC:4.3.2.2] +synonym: "6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity" EXACT [EC:4.3.2.2] +synonym: "adenylosuccinase activity" BROAD [EC:4.3.2.2, GOC:mah] +synonym: "adenylosuccinate lyase activity" BROAD [GOC:mah] +synonym: "N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity" EXACT [EC:4.3.2.2] +synonym: "succino AMP-lyase activity" BROAD [EC:4.3.2.2, GOC:mah] +xref: EC:4.3.2.2 +xref: KEGG_REACTION:R01083 +xref: MetaCyc:AMPSYN-RXN +xref: Reactome:R-HSA-73800 "SAICAR => AICAR + Fumarate" +xref: Reactome:R-HSA-73828 "adenylosuccinate => adenosine 5'-monophosphate + fumarate" +xref: RHEA:16853 +is_a: GO:0016842 ! amidine-lyase activity + +[Term] +id: GO:0004019 +name: adenylosuccinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate." [EC:6.3.4.4, RHEA:15753] +synonym: "adenylosuccinate synthetase activity" EXACT [EC:6.3.4.4] +synonym: "IMP--aspartate ligase activity" EXACT [EC:6.3.4.4] +synonym: "IMP:L-aspartate ligase (GDP-forming)" EXACT [EC:6.3.4.4] +synonym: "succino-AMP synthetase activity" EXACT [EC:6.3.4.4] +synonym: "succinoadenylic kinosynthetase activity" EXACT [EC:6.3.4.4] +xref: EC:6.3.4.4 +xref: KEGG_REACTION:R01135 +xref: MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN +xref: Reactome:R-HSA-111524 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]" +xref: RHEA:15753 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004020 +name: adenylylsulfate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate." [EC:2.7.1.25] +synonym: "5'-phosphoadenosine sulfate kinase activity" EXACT [EC:2.7.1.25] +synonym: "adenosine 5'-phosphosulfate kinase activity" EXACT [EC:2.7.1.25] +synonym: "adenosine phosphosulfate kinase activity" EXACT [EC:2.7.1.25] +synonym: "adenosine phosphosulfokinase activity" EXACT [EC:2.7.1.25] +synonym: "adenosine-5'-phosphosulfate 3'-phosphotransferase activity" EXACT [] +synonym: "adenosine-5'-phosphosulfate-3'-phosphokinase activity" EXACT [EC:2.7.1.25] +synonym: "adenosine-5'-phosphosulphate 3'-phosphotransferase activity" EXACT [] +synonym: "adenylyl-sulfate kinase activity" EXACT [] +synonym: "adenylyl-sulphate kinase activity" EXACT [] +synonym: "adenylylsulfate kinase (phosphorylating)" EXACT [EC:2.7.1.25] +synonym: "APS kinase activity" EXACT [EC:2.7.1.25] +synonym: "ATP:adenylyl-sulfate 3'-phosphotransferase activity" EXACT [EC:2.7.1.25] +xref: EC:2.7.1.25 +xref: MetaCyc:ADENYLYLSULFKIN-RXN +xref: Reactome:R-HSA-174389 "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS" +xref: Reactome:R-HSA-3560785 "Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS" +xref: RHEA:24152 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004021 +name: L-alanine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate." [EC:2.6.1.2, RHEA:19453] +synonym: "alanine aminotransferase activity" BROAD [] +synonym: "alanine transaminase activity" BROAD [EC:2.6.1.2] +synonym: "alanine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.2] +synonym: "alanine-pyruvate aminotransferase activity" EXACT [EC:2.6.1.2] +synonym: "ALT" RELATED [EC:2.6.1.2] +synonym: "beta-alanine aminotransferase" BROAD [EC:2.6.1.2] +synonym: "glutamic acid-pyruvic acid transaminase activity" EXACT [EC:2.6.1.2] +synonym: "glutamic--alanine transaminase activity" EXACT [EC:2.6.1.2] +synonym: "glutamic--pyruvic transaminase activity" EXACT [EC:2.6.1.2] +synonym: "glutamic-pyruvic aminotransferase activity" EXACT [EC:2.6.1.2] +synonym: "GPT" RELATED [EC:2.6.1.2] +synonym: "L-alanine aminotransferase activity" BROAD [EC:2.6.1.2] +synonym: "L-alanine transaminase activity" BROAD [EC:2.6.1.2] +synonym: "L-alanine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.2] +synonym: "pyruvate transaminase activity" BROAD [EC:2.6.1.2] +synonym: "pyruvate-alanine aminotransferase activity" EXACT [EC:2.6.1.2] +synonym: "pyruvate-glutamate transaminase activity" EXACT [EC:2.6.1.2] +xref: EC:2.6.1.2 +xref: KEGG_REACTION:R00258 +xref: MetaCyc:ALANINE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-507749 "pyruvate + glutamate <=> alanine + alpha-ketoglutarate [GPT2]" +xref: Reactome:R-HSA-507775 "alanine + alpha-ketoglutarate <=> pyruvate + glutamate [GPT2]" +xref: Reactome:R-HSA-70523 "alanine + alpha-ketoglutarate <=> pyruvate + glutamate [GPT]" +xref: Reactome:R-HSA-70524 "pyruvate + glutamate <=> alanine + alpha-ketoglutarate [GPT]" +xref: RHEA:19453 +is_a: GO:0047635 ! alanine-oxo-acid transaminase activity + +[Term] +id: GO:0004022 +name: alcohol dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+." [EC:1.1.1.1] +synonym: "ADH" RELATED [EC:1.1.1.1] +synonym: "alcohol dehydrogenase activity" BROAD [GOC:mah] +synonym: "alcohol:NAD+ oxidoreductase" EXACT [EC:1.1.1.1] +synonym: "aldehyde dehydrogenase (NAD) activity" NARROW [] +synonym: "aldo-keto reductase (NAD) activity" EXACT [] +synonym: "aliphatic alcohol dehydrogenase" NARROW [EC:1.1.1.1] +synonym: "ethanol dehydrogenase" NARROW [EC:1.1.1.1] +synonym: "NAD-dependent alcohol dehydrogenase" EXACT [EC:1.1.1.1] +synonym: "NAD-specific aromatic alcohol dehydrogenase" EXACT [EC:1.1.1.1] +synonym: "NADH-alcohol dehydrogenase" EXACT [EC:1.1.1.1] +synonym: "NADH-aldehyde dehydrogenase" EXACT [EC:1.1.1.1] +synonym: "primary alcohol dehydrogenase" BROAD [EC:1.1.1.1] +synonym: "yeast alcohol dehydrogenase" NARROW [EC:1.1.1.1] +xref: EC:1.1.1.1 +xref: MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN +xref: Reactome:R-HSA-2162078 "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+" +xref: UM-BBD_enzymeID:e0023 +is_a: GO:0018455 ! alcohol dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004023 +name: alcohol dehydrogenase activity, metal ion-independent +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion." [EC:1.1.1.1, GOC:mah] +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity + +[Term] +id: GO:0004024 +name: alcohol dehydrogenase activity, zinc-dependent +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc." [EC:1.1.1.1, GOC:mah] +xref: Reactome:R-HSA-71707 "ethanol + NAD+ => acetaldehyde + NADH + H+" +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity + +[Term] +id: GO:0004025 +name: alcohol dehydrogenase activity, iron-dependent +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron." [EC:1.1.1.1, GOC:mah] +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity + +[Term] +id: GO:0004026 +name: alcohol O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester." [EC:2.3.1.84] +synonym: "AATASE activity" EXACT [EC:2.3.1.84] +synonym: "acetyl-CoA:alcohol O-acetyltransferase activity" EXACT [EC:2.3.1.84] +synonym: "alcohol acetyltransferase activity" EXACT [EC:2.3.1.84] +xref: EC:2.3.1.84 +xref: MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN +is_a: GO:0016413 ! O-acetyltransferase activity +is_a: GO:0034318 ! alcohol O-acyltransferase activity + +[Term] +id: GO:0004027 +name: alcohol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate." [EC:2.8.2.2] +subset: goslim_chembl +synonym: "3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "3-hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "3beta-hydroxy steroid sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "3beta-hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "5alpha-androstenol sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "alcohol sulphotransferase activity" EXACT [] +synonym: "alcohol/hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "dehydroepiandrosterone sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "delta5-3beta-hydroxysteroid sulfokinase activity" EXACT [EC:2.8.2.2] +synonym: "estrogen sulfokinase activity" EXACT [EC:2.8.2.2] +synonym: "estrogen sulfotransferase" BROAD [EC:2.8.2.2] +synonym: "HST" RELATED [EC:2.8.2.2] +synonym: "hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] +synonym: "steroid alcohol sulfotransferase" BROAD [EC:2.8.2.2] +synonym: "steroid sulfokinase activity" EXACT [EC:2.8.2.2] +synonym: "sterol sulfokinase activity" EXACT [EC:2.8.2.2] +synonym: "sterol sulfotransferase activity" EXACT [EC:2.8.2.2] +xref: EC:2.8.2.2 +xref: MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-176494 "SULTs transfer (SO4)2- group to 27HCHOL" +xref: Reactome:R-HSA-176609 "cholesterol + PAPS => cholesterol sulfate + PAP" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0004028 +name: 3-chloroallyl aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid." [UM-BBD_enzymeID:e0432] +xref: Reactome:R-HSA-71260 "ALDH9A1 tetramer dehydrogenates TEABL to form TEABT" +xref: UM-BBD_enzymeID:e0432 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004029 +name: aldehyde dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+." [EC:1.2.1.3] +synonym: "aldehyde dehydrogenase (NAD+)" EXACT [EC:1.2.1.3] +synonym: "aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.3] +synonym: "CoA-independent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "m-methylbenzaldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "NAD-aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "NAD-dependent 4-hydroxynonenal dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "NAD-dependent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "NAD-linked aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +synonym: "propionaldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] +xref: EC:1.2.1.3 +xref: MetaCyc:ALDHDEHYDROG-RXN +xref: Reactome:R-HSA-380608 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid" +xref: Reactome:R-HSA-389609 "ALDH3A2-2 oxidizes pristanal to pristanate" +xref: Reactome:R-HSA-5692261 "ALDH3A2-1 oxidises HD2NAL to PALM" +xref: Reactome:R-HSA-5696091 "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH" +xref: Reactome:R-HSA-6808487 "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG" +xref: Reactome:R-HSA-6808496 "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG" +xref: Reactome:R-HSA-6813749 "ALDH1A1 oxidises GA to DGA" +xref: Reactome:R-HSA-71691 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]" +xref: Reactome:R-HSA-71723 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]" +xref: RHEA:16185 +xref: UM-BBD_enzymeID:e0024 +xref: Wikipedia:Aldehyde_dehydrogenase_(NAD+) +is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004030 +name: aldehyde dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+." [EC:1.2.1.5] +synonym: "aldehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.5] +synonym: "ALDH" RELATED [EC:1.2.1.5] +xref: EC:1.2.1.5 +xref: MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN +xref: Reactome:R-HSA-5692283 "ALD3A1 oxidises 4HPCP to CXPA" +xref: Reactome:R-HSA-5696080 "ALDH3B1 oxidises HXAL to PALM" +xref: Reactome:R-HSA-6808464 "ALDH3B2 oxidises HXAL to PALM" +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004031 +name: aldehyde oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide." [EC:1.2.3.1] +synonym: "aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.1] +synonym: "quinoline oxidase activity" RELATED [EC:1.2.3.1] +xref: EC:1.2.3.1 +xref: MetaCyc:ALDEHYDE-OXIDASE-RXN +xref: Reactome:R-HSA-3204311 "AOX1 oxidises PXL to PDXate" +xref: RHEA:16829 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0004032 +name: alditol:NADP+ 1-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+." [EC:1.1.1.21] +synonym: "aldehyde reductase activity" EXACT [EC:1.1.1.21] +synonym: "aldose reductase activity" EXACT [EC:1.1.1.21] +synonym: "polyol dehydrogenase (NADP(+)) activity" RELATED [EC:1.1.1.21] +xref: EC:1.1.1.21 +xref: KEGG_REACTION:R02820 +xref: MetaCyc:ALDEHYDE-REDUCTASE-RXN +xref: Reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol" +xref: Reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol" +is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity + +[Term] +id: GO:0004033 +name: aldo-keto reductase (NADP) activity +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+." [GOC:ai] +synonym: "alcohol dehydrogenase (NADP+) activity" NARROW [] +synonym: "aldo-keto reductase (NADP+) activity" EXACT [] +synonym: "aldo-keto reductase activity" EXACT [] +synonym: "NADPH-dependent aldo-keto reductase activity" EXACT [GOC:vw] +xref: Reactome:R-HSA-192033 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one" +xref: Reactome:R-HSA-192036 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol" +xref: Reactome:R-HSA-192067 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one" +xref: Reactome:R-HSA-192160 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol" +xref: Reactome:R-HSA-193746 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one" +xref: Reactome:R-HSA-193755 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one" +xref: Reactome:R-HSA-193758 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol" +xref: Reactome:R-HSA-193781 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol" +xref: Reactome:R-HSA-193800 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol" +xref: Reactome:R-HSA-193821 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one" +xref: Reactome:R-HSA-193824 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one" +xref: Reactome:R-HSA-193841 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol" +xref: Reactome:R-HSA-198845 "CYB5A:heme reduces SDA to VitC" +xref: Reactome:R-HSA-2855252 "AKRs reduce RBP2:atRAL to RBP2:atROL" +xref: Reactome:R-HSA-5423637 "AKR dimers reduce AFBDHO to AFBDOH" +xref: Reactome:R-HSA-5692232 "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione" +xref: Reactome:R-HSA-9027531 "Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA" +xref: Reactome:R-HSA-9027562 "Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA" +xref: Reactome:R-HSA-9027598 "Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3" +xref: Reactome:R-HSA-9027600 "Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004034 +name: aldose 1-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose." [EC:5.1.3.3] +synonym: "aldose mutarotase activity" RELATED [EC:5.1.3.3] +synonym: "mutarotase activity" RELATED [EC:5.1.3.3] +xref: EC:5.1.3.3 +xref: MetaCyc:ALDOSE-1-EPIMERASE-RXN +xref: RHEA:10264 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0004035 +name: alkaline phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [EC:3.1.3.1] +synonym: "alkaline phenyl phosphatase activity" EXACT [EC:3.1.3.1] +synonym: "alkaline phosphohydrolase activity" EXACT [EC:3.1.3.1] +synonym: "alkaline phosphomonoesterase activity" EXACT [EC:3.1.3.1] +synonym: "glycerophosphatase activity" BROAD [EC:3.1.3.1] +synonym: "orthophosphoric-monoester phosphohydrolase (alkaline optimum)" EXACT [EC:3.1.3.1] +synonym: "phosphate-monoester phosphohydrolase (alkaline optimum)" EXACT [EC:3.1.3.1] +synonym: "phosphomonoesterase activity" BROAD [EC:3.1.3.1] +xref: EC:3.1.3.1 +xref: MetaCyc:ALKAPHOSPHA-RXN +xref: Reactome:R-HSA-8878787 "ALPI dimer hydrolyses phosphate monoesters" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0004037 +name: allantoicase activity +namespace: molecular_function +def: "Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea." [EC:3.5.3.4, RHEA:11016] +synonym: "allantoate amidinohydrolase activity" EXACT [EC:3.5.3.4] +synonym: "allantoine amidinohydrolase activity" EXACT [] +xref: EC:3.5.3.4 +xref: KEGG_REACTION:R02422 +xref: MetaCyc:ALLANTOICASE-RXN +xref: RHEA:11016 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0004038 +name: allantoinase activity +namespace: molecular_function +def: "Catalysis of the reaction: allantoin + H2O = allantoate." [EC:3.5.2.5] +synonym: "(S)-allantoin amidohydrolase activity" EXACT [EC:3.5.2.5] +xref: EC:3.5.2.5 +xref: MetaCyc:ALLANTOINASE-RXN +xref: RHEA:17029 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0004039 +name: allophanate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+)." [EC:3.5.1.54, RHEA:19029] +synonym: "allophanate lyase activity" EXACT [EC:3.5.1.54] +synonym: "urea-1-carboxylate amidohydrolase activity" EXACT [EC:3.5.1.54] +xref: EC:3.5.1.54 +xref: KEGG_REACTION:R00005 +xref: MetaCyc:ALLOPHANATE-HYDROLASE-RXN +xref: RHEA:19029 +xref: UM-BBD_reactionID:r0848 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004040 +name: amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3." [EC:3.5.1.4] +synonym: "acetamidase activity" EXACT [] +synonym: "acylamidase activity" EXACT [EC:3.5.1.4] +synonym: "acylamide amidohydrolase activity" EXACT [EC:3.5.1.4] +synonym: "acylase activity" EXACT [EC:3.5.1.4] +synonym: "amidohydrolase activity" EXACT [EC:3.5.1.4] +synonym: "fatty acylamidase activity" EXACT [EC:3.5.1.4] +synonym: "N-acetylaminohydrolase activity" EXACT [EC:3.5.1.4] +xref: EC:3.5.1.4 +xref: MetaCyc:AMIDASE-RXN +xref: UM-BBD_enzymeID:e0068 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004042 +name: acetyl-CoA:L-glutamate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)." [EC:2.3.1.1, RHEA:24292] +synonym: "acetylglutamate acetylglutamate synthetase activity" EXACT [EC:2.3.1.1] +synonym: "AGAS" RELATED [EC:2.3.1.1] +synonym: "amino acid acetyltransferase activity" EXACT [EC:2.3.1.1] +synonym: "amino-acid N-acetyltransferase activity" BROAD [EC:2.3.1.1] +synonym: "N-acetylglutamate synthase activity" BROAD [EC:2.3.1.1] +xref: EC:2.3.1.1 +xref: KEGG_REACTION:R00259 +xref: MetaCyc:N-ACETYLTRANSFER-RXN +xref: Reactome:R-HSA-70542 "glutamate + acetyl CoA => N-acetyl glutamate + CoA" +xref: RHEA:24292 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004043 +name: L-aminoadipate-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+." [EC:1.2.1.31] +synonym: "2-aminoadipate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] +synonym: "2-aminoadipic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] +synonym: "AAR" EXACT [EC:1.2.1.31] +synonym: "alpha-aminoadipate reductase activity" EXACT [EC:1.2.1.31] +synonym: "alpha-aminoadipate-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] +synonym: "aminoadipate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] +synonym: "aminoadipate-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] +synonym: "L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase" EXACT [EC:1.2.1.31] +synonym: "L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity" EXACT [EC:1.2.1.31] +synonym: "L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity" EXACT [EC:1.2.1.31] +synonym: "L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity" EXACT [EC:1.2.1.31] +xref: EC:1.2.1.31 +xref: MetaCyc:1.2.1.31-RXN +xref: Reactome:R-HSA-70941 "alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+" +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004044 +name: amidophosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O." [EC:2.4.2.14, RHEA:14905] +synonym: "5'-phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "5-phosphoribosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)" EXACT [EC:2.4.2.14] +synonym: "5-phosphororibosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "glutamine 5-phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "glutamine phosphoribosyldiphosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "glutamine phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "phosphoribose pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "phosphoribosyl pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "phosphoribosyldiphosphate 5-amidotransferase activity" EXACT [EC:2.4.2.14] +synonym: "phosphoribosylpyrophosphate glutamyl amidotransferase activity" EXACT [EC:2.4.2.14] +xref: EC:2.4.2.14 +xref: KEGG_REACTION:R01072 +xref: MetaCyc:PRPPAMIDOTRANS-RXN +xref: Reactome:R-HSA-73815 "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate" +xref: RHEA:14905 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004045 +name: aminoacyl-tRNA hydrolase activity +namespace: molecular_function +alt_id: GO:0019850 +alt_id: GO:0019851 +def: "Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA." [EC:3.1.1.29] +synonym: "aminoacyl-transfer ribonucleate hydrolase activity" EXACT [EC:3.1.1.29] +synonym: "aminoacyl-tRNA aminoacylhydrolase activity" EXACT [EC:3.1.1.29] +synonym: "aminoacyl-tRNA hydrolase reaction" EXACT [] +synonym: "D-tyrosyl-tRNA hydrolase activity" NARROW [PMID:15292242] +synonym: "N-substituted aminoacyl transfer RNA hydrolase activity" EXACT [EC:3.1.1.29] +synonym: "peptidyl-tRNA hydrolase activity" EXACT [EC:3.1.1.29] +xref: EC:3.1.1.29 +xref: MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0004046 +name: aminoacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid." [EC:3.5.1.14] +synonym: "acylase I activity" NARROW [EC:3.5.1.14] +synonym: "alpha-N-acylaminoacid hydrolase activity" EXACT [EC:3.5.1.14] +synonym: "amido acid deacylase activity" EXACT [EC:3.5.1.14] +synonym: "aminoacylase I activity" NARROW [EC:3.5.1.14] +synonym: "benzamidase activity" RELATED [EC:3.5.1.14] +synonym: "dehydropeptidase II activity" NARROW [EC:3.5.1.14] +synonym: "hippurase activity" EXACT [EC:3.5.1.14] +synonym: "histozyme activity" RELATED [EC:3.5.1.14] +synonym: "L-amino-acid acylase activity" EXACT [EC:3.5.1.14] +synonym: "L-aminoacylase activity" EXACT [EC:3.5.1.14] +synonym: "long acyl amidoacylase activity" EXACT [EC:3.5.1.14] +synonym: "N-acyl-L-amino-acid amidohydrolase activity" EXACT [EC:3.5.1.14] +synonym: "short acyl amidoacylase activity" EXACT [EC:3.5.1.14] +xref: EC:3.5.1.14 +xref: MetaCyc:AMINOACYLASE-RXN +xref: Reactome:R-HSA-5433074 "ACY1:Zn2+ dimer hydrolyses mercapturic acids" +xref: Reactome:R-HSA-5579081 "Defective ACY1 does not hydrolyse mercapturic acids" +xref: Reactome:R-HSA-9638046 "ACY3:Zn2+ dimer hydrolyses mercapturic acids" +xref: RHEA:15565 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004047 +name: aminomethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein." [EC:2.1.2.10] +synonym: "glycine synthase activity" RELATED [EC:2.1.2.10] +synonym: "glycine-cleavage system T-protein activity" RELATED [EC:2.1.2.10] +synonym: "protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] +synonym: "protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] +synonym: "S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] +synonym: "T-protein" RELATED [EC:2.1.2.10] +synonym: "tetrahydrofolate aminomethyltransferase activity" EXACT [EC:2.1.2.10] +xref: EC:2.1.2.10 +xref: MetaCyc:GCVT-RXN +xref: Reactome:R-HSA-5693977 "AMT transfers NH2CH2 from GCSH:SAMDLL to THF" +xref: RHEA:16945 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0004048 +name: anthranilate phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate." [EC:2.4.2.18, RHEA:11768] +synonym: "anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] +synonym: "anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] +synonym: "anthranilate-PP-ribose-P phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] +synonym: "N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.18] +synonym: "phosphoribosyl-anthranilate diphosphorylase activity" EXACT [EC:2.4.2.18] +synonym: "phosphoribosyl-anthranilate pyrophosphorylase activity" EXACT [EC:2.4.2.18] +synonym: "phosphoribosylanthranilate pyrophosphorylase activity" EXACT [EC:2.4.2.18] +synonym: "phosphoribosylanthranilate transferase activity" EXACT [EC:2.4.2.18] +synonym: "PRT" RELATED [EC:2.4.2.18] +xref: EC:2.4.2.18 +xref: KEGG_REACTION:R01073 +xref: MetaCyc:PRTRANS-RXN +xref: RHEA:11768 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004049 +name: anthranilate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate." [EC:4.1.3.27] +synonym: "anthranilate synthetase activity" EXACT [EC:4.1.3.27] +synonym: "chorismate pyruvate-lyase (amino-accepting) activity" EXACT [EC:4.1.3.27] +xref: EC:4.1.3.27 +xref: MetaCyc:ANTHRANSYN-RXN +xref: RHEA:21732 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0004050 +name: obsolete apyrase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate." [EC:3.6.1.5, MetaCyc:APYRASE-RXN] +comment: This term was made obsolete because it represents a gene product which can catalyze two reactions. +synonym: "apyrase activity" EXACT [] +is_obsolete: true +consider: GO:0017110 +consider: GO:0017111 + +[Term] +id: GO:0004051 +name: arachidonate 5-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate." [EC:1.13.11.34, RHEA:32307] +synonym: "5-delta-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "5-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "5Delta-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "arachidonate:oxygen 5-oxidoreductase activity" EXACT [EC:1.13.11.34] +synonym: "arachidonic 5-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "arachidonic acid 5-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "C-5-lipoxygenase activity" RELATED [EC:1.13.11.34] +synonym: "delta(5)-lipoxygenase activity" RELATED [EC:1.13.11.34] +synonym: "delta5-lipoxygenase activity" EXACT [EC:1.13.11.34] +synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.34] +synonym: "leukotriene-A(4) synthase activity" NARROW [EC:1.13.11.34] +synonym: "leukotriene-A4 synthase activity" EXACT [EC:1.13.11.34] +synonym: "LTA synthase activity" NARROW [EC:1.13.11.34] +xref: EC:1.13.11.34 +xref: MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN +xref: Reactome:R-HSA-265296 "Arachidonic acid is oxidised to 5S-HpETE by ALOX5" +xref: Reactome:R-HSA-266051 "5S-HpETE is dehydrated to LTA4 by ALOX5" +xref: Reactome:R-HSA-9018858 "ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE" +xref: Reactome:R-HSA-9018859 "ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE" +xref: Reactome:R-HSA-9018863 "ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE" +xref: Reactome:R-HSA-9018894 "ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE" +xref: Reactome:R-HSA-9020251 "ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA" +xref: Reactome:R-HSA-9020255 "ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA" +xref: Reactome:R-HSA-9020256 "ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA" +xref: Reactome:R-HSA-9020259 "ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA" +xref: Reactome:R-HSA-9020264 "ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA" +xref: Reactome:R-HSA-9020277 "ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA" +xref: Reactome:R-HSA-9020278 "ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA" +xref: Reactome:R-HSA-9020282 "ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA" +xref: Reactome:R-HSA-9024997 "ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA" +xref: Reactome:R-HSA-9025995 "ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3" +xref: Reactome:R-HSA-9025996 "ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3" +xref: Reactome:R-HSA-9025999 "ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3" +xref: Reactome:R-HSA-9026005 "ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA" +xref: Reactome:R-HSA-9026405 "ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4" +xref: Reactome:R-HSA-9027624 "ALOX5 oxidises DHA to 7-HDHA" +xref: Reactome:R-HSA-9027628 "ALOX5 oxidises EPA to 5-HEPE" +xref: Reactome:R-HSA-9027633 "ALOX5 oxidises DPAn-3 to 7-HDPAn-3" +xref: RHEA:32307 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0004052 +name: arachidonate 12(S)-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate." [EC:1.13.11.31, RHEA:10428] +synonym: "12-lipoxygenase activity" RELATED [EC:1.13.11.31] +synonym: "12Delta-lipoxygenase activity" EXACT [EC:1.13.11.31] +synonym: "12S-lipoxygenase activity" EXACT [EC:1.13.11.31] +synonym: "arachidonate:oxygen 12-oxidoreductase activity" EXACT [EC:1.13.11.31] +synonym: "C-12 lipoxygenase activity" EXACT [EC:1.13.11.31] +synonym: "delta12-lipoxygenase activity" EXACT [EC:1.13.11.31] +synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.31] +synonym: "LTA4 synthase activity" EXACT [EC:1.13.11.31] +xref: EC:1.13.11.31 +xref: KEGG_REACTION:R01596 +xref: MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN +xref: Reactome:R-HSA-2161948 "Arachidonic acid is converted to 12-oxoETE by ALOX12" +xref: Reactome:R-HSA-2161950 "Arachidonic acid is oxidised to 12R-HpETE by ALOX12B" +xref: Reactome:R-HSA-2161964 "Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15" +xref: Reactome:R-HSA-9024983 "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA" +xref: Reactome:R-HSA-9025957 "ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6" +xref: Reactome:R-HSA-9026006 "ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3" +xref: Reactome:R-HSA-9026007 "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3" +xref: RHEA:10428 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0004053 +name: arginase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea." [EC:3.5.3.1] +synonym: "arginine amidinase activity" EXACT [EC:3.5.3.1] +synonym: "arginine transamidinase activity" EXACT [EC:3.5.3.1] +synonym: "canavanase activity" EXACT [EC:3.5.3.1] +synonym: "L-arginase activity" EXACT [EC:3.5.3.1] +synonym: "L-arginine amidinohydrolase activity" EXACT [EC:3.5.3.1] +xref: EC:3.5.3.1 +xref: MetaCyc:ARGINASE-RXN +xref: Reactome:R-HSA-452036 "arginine + H2O => ornithine + urea [ARG2]" +xref: Reactome:R-HSA-70569 "arginine + H2O => ornithine + urea [ARG1]" +xref: RHEA:20569 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0004054 +name: arginine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+)." [EC:2.7.3.3, RHEA:22940] +synonym: "adenosine 5'-triphosphate-arginine phosphotransferase activity" EXACT [EC:2.7.3.3] +synonym: "adenosine 5'-triphosphate:L-arginine" RELATED [EC:2.7.3.3] +synonym: "arginine phosphokinase activity" EXACT [EC:2.7.3.3] +synonym: "ATP:L-arginine N-phosphotransferase activity" EXACT [EC:2.7.3.3] +xref: EC:2.7.3.3 +xref: KEGG_REACTION:R00554 +xref: MetaCyc:ARGININE-KINASE-RXN +xref: RHEA:22940 +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0004055 +name: argininosuccinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate." [EC:6.3.4.5] +synonym: "arginine succinate synthetase activity" EXACT [EC:6.3.4.5] +synonym: "argininosuccinate synthetase activity" EXACT [EC:6.3.4.5] +synonym: "argininosuccinic acid synthetase activity" EXACT [EC:6.3.4.5] +synonym: "arginosuccinate synthetase activity" EXACT [EC:6.3.4.5] +synonym: "citrulline--aspartate ligase activity" EXACT [EC:6.3.4.5] +synonym: "L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [EC:6.3.4.5] +xref: EC:6.3.4.5 +xref: MetaCyc:ARGSUCCINSYN-RXN +xref: Reactome:R-HSA-70577 "ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA" +xref: RHEA:10932 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004056 +name: argininosuccinate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine." [EC:4.3.2.1] +synonym: "2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)" EXACT [EC:4.3.2.1] +synonym: "2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)" EXACT [EC:4.3.2.1] +synonym: "arginine-succinate lyase activity" EXACT [EC:4.3.2.1] +synonym: "argininosuccinic acid lyase activity" EXACT [EC:4.3.2.1] +synonym: "arginosuccinase activity" EXACT [EC:4.3.2.1] +synonym: "N-(L-argininosuccinate) arginine-lyase activity" EXACT [EC:4.3.2.1] +synonym: "omega-N-(L-arginino)succinate arginine-lyase activity" EXACT [EC:4.3.2.1] +xref: EC:4.3.2.1 +xref: MetaCyc:ARGSUCCINLYA-RXN +xref: Reactome:R-HSA-70573 "argininosuccinate <=> fumarate + arginine" +xref: RHEA:24020 +is_a: GO:0016842 ! amidine-lyase activity + +[Term] +id: GO:0004057 +name: arginyltransferase activity +namespace: molecular_function +alt_id: GO:0042172 +def: "Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein." [EC:2.3.2.8] +synonym: "arginine transferase activity" EXACT [EC:2.3.2.8] +synonym: "arginyl-transfer ribonucleate-protein aminoacyltransferase activity" EXACT [EC:2.3.2.8] +synonym: "arginyl-transfer ribonucleate-protein transferase activity" EXACT [EC:2.3.2.8] +synonym: "arginyl-tRNA protein transferase activity" EXACT [EC:2.3.2.8] +synonym: "arginyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.8] +synonym: "arginyl-tRNA-protein transferase activity" EXACT [] +synonym: "L-arginyl-tRNA:protein arginyltransferase activity" EXACT [EC:2.3.2.8] +xref: EC:2.3.2.8 +xref: MetaCyc:ARGINYLTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups +relationship: part_of GO:0016598 ! protein arginylation + +[Term] +id: GO:0004058 +name: aromatic-L-amino-acid decarboxylase activity +namespace: molecular_function +alt_id: GO:0016400 +def: "Catalysis of the reaction: L-amino acid + H+ = R-H + CO2." [EC:4.1.1.28] +synonym: "5-hydroxytryptophan decarboxylase activity" NARROW [EC:4.1.1.28] +synonym: "aromatic amino acid decarboxylase activity" EXACT [EC:4.1.1.28] +synonym: "aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)" NARROW [EC:4.1.1.28] +synonym: "aromatic-L-amino-acid carboxy-lyase activity" EXACT [EC:4.1.1.28] +synonym: "DOPA decarboxylase activity" NARROW [EC:4.1.1.28] +synonym: "hydroxytryptophan decarboxylase activity" NARROW [EC:4.1.1.28] +synonym: "L-DOPA decarboxylase activity" NARROW [EC:4.1.1.28] +synonym: "tryptophan decarboxylase activity" NARROW [EC:4.1.1.28] +xref: EC:4.1.1.28 +xref: MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-209859 "Decarboxylation of 5-hydroxytryptophan forms serotonin" +xref: Reactome:R-HSA-209924 "Dopa is decarboxylated to dopamine" +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004059 +name: aralkylamine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine." [EC:2.3.1.87] +synonym: "AANAT activity" EXACT [EC:2.3.1.87] +synonym: "acetyl-CoA:2-arylethylamine N-acetyltransferase activity" EXACT [EC:2.3.1.87] +synonym: "arylalkylamine N-acetyltransferase activity" EXACT [EC:2.3.1.87] +synonym: "melatonin rhythm enzyme activity" RELATED [EC:2.3.1.87] +synonym: "serotonin acetylase activity" NARROW [EC:2.3.1.87] +synonym: "serotonin acetyltransferase activity" NARROW [EC:2.3.1.87] +synonym: "serotonin N-acetyltransferase activity" NARROW [EC:2.3.1.87] +xref: EC:2.3.1.87 +xref: MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-209792 "N-acetylation of serotonin" +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004060 +name: arylamine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine." [EC:2.3.1.5] +synonym: "2-naphthylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "4-aminobiphenyl N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "acetyl CoA-arylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "acetyl-CoA:arylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "arylamine acetylase activity" EXACT [EC:2.3.1.5] +synonym: "arylamine acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "beta-naphthylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "indoleamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] +synonym: "p-aminosalicylate N-acetyltransferase activity" EXACT [EC:2.3.1.5] +xref: EC:2.3.1.5 +xref: MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-174963 "NAT1 acetylation" +xref: Reactome:R-HSA-174967 "NAT2 acetylation" +xref: UM-BBD_enzymeID:e0341 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004061 +name: arylformamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine." [EC:3.5.1.9] +synonym: "aryl-formylamine amidohydrolase activity" EXACT [EC:3.5.1.9] +synonym: "formamidase I" RELATED [EC:3.5.1.9] +synonym: "formamidase II" RELATED [EC:3.5.1.9] +synonym: "formylase activity" EXACT [EC:3.5.1.9] +synonym: "formylkynureninase activity" EXACT [EC:3.5.1.9] +synonym: "formylkynurenine formamidase activity" EXACT [EC:3.5.1.9] +synonym: "kynurenine formamidase activity" EXACT [EC:3.5.1.9] +xref: EC:3.5.1.9 +xref: MetaCyc:ARYLFORMAMIDASE-RXN +xref: Reactome:R-HSA-71189 "AFMID hydrolyses NFK to L-KYN" +xref: RHEA:13009 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004062 +name: aryl sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate." [EC:2.8.2.1] +subset: goslim_chembl +synonym: "1-naphthol phenol sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "2-naphtholsulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "4-nitrocatechol sulfokinase activity" EXACT [EC:2.8.2.1] +synonym: "aryl sulphotransferase activity" EXACT [] +synonym: "arylsulfotransferase" BROAD [EC:2.8.2.1] +synonym: "dopamine sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "p-nitrophenol sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "phenol sulfokinase activity" EXACT [EC:2.8.2.1] +synonym: "phenol sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "PST" RELATED [EC:2.8.2.1] +synonym: "ritodrine sulfotransferase activity" EXACT [EC:2.8.2.1] +synonym: "sulfokinase activity" RELATED [EC:2.8.2.1] +xref: EC:2.8.2.1 +xref: MetaCyc:ARYL-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-158468 "SULT1A1 dimer sulfonates PARA to PARA-SO4" +xref: Reactome:R-HSA-158849 "Phenol can form a sulfate conjugate" +xref: Reactome:R-HSA-158860 "SULT1A1 dimer sulfonates NHABP" +xref: Reactome:R-HSA-159358 "SULT1A3,4 dimers sulfate DA to DAOS" +xref: Reactome:R-HSA-176474 "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP" +xref: Reactome:R-HSA-176585 "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP" +xref: Reactome:R-HSA-176646 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0004063 +name: aryldialkylphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol." [EC:3.1.8.1] +synonym: "A-esterase activity" BROAD [EC:3.1.8.1] +synonym: "aryltriphosphatase activity" EXACT [EC:3.1.8.1] +synonym: "aryltriphosphate dialkylphosphohydrolase activity" EXACT [EC:3.1.8.1] +synonym: "esterase B1" RELATED [EC:3.1.8.1] +synonym: "esterase E4" RELATED [EC:3.1.8.1] +synonym: "OPH" RELATED [EC:3.1.8.1] +synonym: "organophosphate esterase activity" EXACT [EC:3.1.8.1] +synonym: "organophosphate hydrolase activity" EXACT [EC:3.1.8.1] +synonym: "organophosphorus acid anhydrase activity" EXACT [EC:3.1.8.1] +synonym: "organophosphorus hydrolase activity" EXACT [EC:3.1.8.1] +synonym: "paraoxon esterase activity" EXACT [EC:3.1.8.1] +synonym: "paraoxon hydrolase activity" BROAD [EC:3.1.8.1] +synonym: "paraoxonase activity" BROAD [EC:3.1.8.1] +synonym: "phosphotriesterase activity" EXACT [EC:3.1.8.1] +synonym: "pirimiphos-methyloxon esterase activity" EXACT [EC:3.1.8.1] +xref: EC:3.1.8.1 +xref: MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN +xref: UM-BBD_enzymeID:e0054 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0004064 +name: arylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate." [EC:3.1.1.2] +synonym: "A-esterase activity" BROAD [EC:3.1.1.2] +synonym: "aromatic esterase" NARROW [EC:3.1.1.2] +synonym: "aryl-ester hydrolase" NARROW [EC:3.1.1.2] +synonym: "paraoxonase activity" BROAD [EC:3.1.1.2] +xref: EC:3.1.1.2 +xref: MetaCyc:ARYLESTERASE-RXN +xref: UM-BBD_reactionID:r0757 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004065 +name: arylsulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate." [EC:3.1.6.1] +synonym: "4-methylumbelliferyl sulfatase activity" EXACT [EC:3.1.6.1] +synonym: "aryl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.1] +synonym: "aryl-sulfate sulphohydrolase activity" EXACT [EC:3.1.6.1] +synonym: "aryl-sulphate sulphohydrolase activity" EXACT [EC:3.1.6.1] +synonym: "arylsulfohydrolase activity" EXACT [EC:3.1.6.1] +synonym: "arylsulphatase activity" EXACT [] +synonym: "estrogen sulfatase activity" EXACT [EC:3.1.6.1] +synonym: "nitrocatechol sulfatase activity" EXACT [EC:3.1.6.1] +synonym: "p-nitrophenyl sulfatase activity" EXACT [EC:3.1.6.1] +synonym: "phenolsulfatase activity" EXACT [EC:3.1.6.1] +synonym: "phenylsulfatase activity" EXACT [EC:3.1.6.1] +synonym: "sulfatase activity" RELATED [EC:3.1.6.1] +xref: EC:3.1.6.1 +xref: MetaCyc:ARYLSULFAT-RXN +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0004066 +name: asparagine synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate." [EC:6.3.5.4, RHEA:12228] +synonym: "AS" RELATED [EC:6.3.5.4] +synonym: "AS-B activity" EXACT [EC:6.3.5.4] +synonym: "asparagine synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.4] +synonym: "asparagine synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.4] +synonym: "asparagine synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.4] +synonym: "asparagine synthetase B activity" EXACT [EC:6.3.5.4] +synonym: "glutamine-dependent asparagine synthetase activity" EXACT [EC:6.3.5.4] +synonym: "L-aspartate:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.4] +xref: EC:6.3.5.4 +xref: MetaCyc:ASNSYNB-RXN +xref: Reactome:R-HSA-70599 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]" +xref: RHEA:12228 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0004067 +name: asparaginase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3." [EC:3.5.1.1] +synonym: "alpha-asparaginase activity" EXACT [EC:3.5.1.1] +synonym: "asparaginase II" RELATED [EC:3.5.1.1] +synonym: "colaspase activity" EXACT [EC:3.5.1.1] +synonym: "crasnitin" RELATED [EC:3.5.1.1] +synonym: "elspar" RELATED [EC:3.5.1.1] +synonym: "L-asparaginase activity" EXACT [EC:3.5.1.1] +synonym: "L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.1] +synonym: "leunase activity" EXACT [EC:3.5.1.1] +xref: EC:3.5.1.1 +xref: MetaCyc:ASPARAGHYD-RXN +xref: Reactome:R-HSA-6797627 "ASPG hydrolyses L-Asn to L-Asp" +xref: RHEA:21016 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004068 +name: aspartate 1-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate = beta-alanine + CO2." [EC:4.1.1.11] +synonym: "aspartate alpha-decarboxylase activity" EXACT [EC:4.1.1.11] +synonym: "aspartic alpha-decarboxylase" BROAD [EC:4.1.1.11] +synonym: "L-aspartate 1-carboxy-lyase (beta-alanine-forming)" EXACT [EC:4.1.1.11] +synonym: "L-aspartate 1-carboxy-lyase activity" EXACT [EC:4.1.1.11] +synonym: "L-aspartate alpha-decarboxylase activity" EXACT [EC:4.1.1.11] +xref: EC:4.1.1.11 +xref: MetaCyc:ASPDECARBOX-RXN +xref: MetaCyc:PWY-5155 +xref: RHEA:19497 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004069 +name: L-aspartate:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate." [EC:2.6.1.1] +synonym: "2-oxoglutarate-glutamate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "AAT" RELATED [EC:2.6.1.1] +synonym: "aspartate alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.1] +synonym: "aspartate aminotransferase activity" BROAD [] +synonym: "aspartate transaminase activity" BROAD [EC:2.6.1.1] +synonym: "aspartate-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.1] +synonym: "aspartate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "aspartic acid aminotransferase activity" BROAD [EC:2.6.1.1] +synonym: "aspartic aminotransferase activity" BROAD [EC:2.6.1.1] +synonym: "aspartyl aminotransferase activity" BROAD [EC:2.6.1.1] +synonym: "AspT" RELATED [EC:2.6.1.1] +synonym: "glutamate oxaloacetate transaminase activity" EXACT [EC:2.6.1.1] +synonym: "glutamate-oxalacetate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "glutamate-oxalate transaminase activity" EXACT [EC:2.6.1.1] +synonym: "glutamic oxalic transaminase activity" EXACT [EC:2.6.1.1] +synonym: "glutamic--aspartic transaminase activity" EXACT [EC:2.6.1.1] +synonym: "glutamic--oxaloacetic transaminase activity" EXACT [EC:2.6.1.1] +synonym: "glutamic-aspartic aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "glutamic-oxalacetic transaminase activity" EXACT [EC:2.6.1.1] +synonym: "GOT (enzyme)" RELATED [EC:2.6.1.1] +synonym: "L-aspartate transaminase activity" BROAD [EC:2.6.1.1] +synonym: "L-aspartate-2-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "L-aspartate-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "L-aspartate-2-oxoglutarate-transaminase activity" EXACT [EC:2.6.1.1] +synonym: "L-aspartate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.1] +synonym: "L-aspartic aminotransferase activity" BROAD [EC:2.6.1.1] +synonym: "oxaloacetate transferase activity" EXACT [EC:2.6.1.1] +synonym: "oxaloacetate-aspartate aminotransferase activity" EXACT [EC:2.6.1.1] +synonym: "transaminase A activity" RELATED [EC:2.6.1.1] +xref: EC:2.6.1.1 +xref: KEGG_REACTION:R00355 +xref: MetaCyc:ASPAMINOTRANS-RXN +xref: Reactome:R-HSA-70581 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]" +xref: Reactome:R-HSA-70592 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1]" +xref: Reactome:R-HSA-70596 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT2]" +xref: Reactome:R-HSA-70613 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]" +xref: RHEA:21824 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004070 +name: aspartate carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate." [EC:2.1.3.2, RHEA:20013] +synonym: "aspartate carbamyltransferase activity" EXACT [EC:2.1.3.2] +synonym: "aspartate transcarbamoylase activity" EXACT [EC:2.1.3.2] +synonym: "aspartate transcarbamylase activity" EXACT [EC:2.1.3.2] +synonym: "aspartic acid transcarbamoylase activity" EXACT [EC:2.1.3.2] +synonym: "aspartic carbamyltransferase activity" EXACT [EC:2.1.3.2] +synonym: "aspartic transcarbamylase activity" EXACT [EC:2.1.3.2] +synonym: "ATCase activity" EXACT [EC:2.1.3.2] +synonym: "carbamoyl-phosphate:L-aspartate carbamoyltransferase activity" EXACT [EC:2.1.3.2] +synonym: "carbamoylaspartotranskinase activity" EXACT [EC:2.1.3.2] +synonym: "carbamylaspartotranskinase activity" EXACT [EC:2.1.3.2] +synonym: "L-aspartate transcarbamoylase activity" EXACT [EC:2.1.3.2] +synonym: "L-aspartate transcarbamylase activity" EXACT [EC:2.1.3.2] +xref: EC:2.1.3.2 +xref: KEGG_REACTION:R01397 +xref: MetaCyc:ASPCARBTRANS-RXN +xref: Reactome:R-HSA-73573 "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate" +xref: RHEA:20013 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0004071 +name: aspartate-ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine." [EC:6.3.1.1] +synonym: "asparagine synthetase activity" EXACT [EC:6.3.1.1] +synonym: "L-asparagine synthetase activity" EXACT [EC:6.3.1.1] +synonym: "L-aspartate:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.1] +xref: EC:6.3.1.1 +xref: MetaCyc:ASNSYNA-RXN +xref: RHEA:11372 +is_a: GO:0016211 ! ammonia ligase activity + +[Term] +id: GO:0004072 +name: aspartate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+)." [EC:2.7.2.4, RHEA:23776] +synonym: "aspartic kinase activity" EXACT [EC:2.7.2.4] +synonym: "aspartokinase activity" EXACT [EC:2.7.2.4] +synonym: "ATP:L-aspartate 4-phosphotransferase activity" EXACT [EC:2.7.2.4] +synonym: "beta-aspartokinase activity" EXACT [EC:2.7.2.4] +xref: EC:2.7.2.4 +xref: KEGG_REACTION:R00480 +xref: MetaCyc:ASPARTATEKIN-RXN +xref: RHEA:23776 +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0004073 +name: aspartate-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH." [EC:1.2.1.11, RHEA:24284] +synonym: "ASA dehydrogenase activity" EXACT [EC:1.2.1.11] +synonym: "aspartate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] +synonym: "aspartic beta-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] +synonym: "aspartic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] +synonym: "L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.11] +synonym: "L-aspartate-beta-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] +synonym: "L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)" EXACT [EC:1.2.1.11] +xref: EC:1.2.1.11 +xref: KEGG_REACTION:R02291 +xref: MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN +xref: RHEA:24284 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004074 +name: biliverdin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+." [EC:1.3.1.24] +synonym: "bilirubin:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.24] +xref: EC:1.3.1.24 +xref: MetaCyc:BILIVERDIN-REDUCTASE-RXN +xref: Reactome:R-HSA-189384 "Biliverdin is reduced to bilirubin" +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004075 +name: biotin carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein." [EC:6.3.4.14] +synonym: "biotin carboxylase (component of acetyl CoA carboxylase) activity" EXACT [EC:6.3.4.14] +synonym: "biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity" EXACT [EC:6.3.4.14] +xref: EC:6.3.4.14 +xref: MetaCyc:BIOTIN-CARBOXYL-RXN +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004076 +name: biotin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+)." [EC:2.8.1.6, RHEA:22060] +synonym: "biotin synthetase activity" EXACT [EC:2.8.1.6] +synonym: "dethiobiotin:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.6] +xref: EC:2.8.1.6 +xref: KEGG_REACTION:R01078 +xref: MetaCyc:2.8.1.6-RXN +xref: RHEA:22060 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0004077 +name: biotin-[acetyl-CoA-carboxylase] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming))." [EC:6.3.4.15] +synonym: "acetyl CoA holocarboxylase synthetase activity" EXACT [EC:6.3.4.15] +synonym: "acetyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.15] +synonym: "acetyl-CoA carboxylase biotin holoenzyme synthetase activity" EXACT [EC:6.3.4.15] +synonym: "biotin holoenzyme synthetase activity" EXACT [EC:6.3.4.15] +synonym: "biotin--[acetyl-CoA carboxylase] synthetase activity" EXACT [EC:6.3.4.15] +synonym: "biotin--protein ligase activity" RELATED [EC:6.3.4.15] +synonym: "biotin-acetyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.15] +synonym: "biotin-acetyl-CoA carboxylase synthetase" BROAD [EC:6.3.4.15] +synonym: "biotin-acetyl-CoA-carboxylase ligase activity" EXACT [EC:6.3.4.15] +synonym: "biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.15] +synonym: "biotin:apocarboxylase ligase activity" EXACT [EC:6.3.4.15] +synonym: "HCS" RELATED [EC:6.3.4.15] +xref: EC:6.3.4.15 +xref: MetaCyc:BIOTINLIG-RXN +is_a: GO:0018271 ! biotin-protein ligase activity + +[Term] +id: GO:0004078 +name: biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming))." [EC:6.3.4.11] +synonym: "beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.11] +synonym: "biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity" EXACT [EC:6.3.4.11] +synonym: "biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.11] +synonym: "biotin-methylcrotonoyl-CoA-carboxylase ligase activity" EXACT [EC:6.3.4.11] +synonym: "biotin-methylcrotonoyl-CoA-carboxylase synthetase" BROAD [EC:6.3.4.11] +synonym: "biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.11] +xref: EC:6.3.4.11 +xref: MetaCyc:6.3.4.11-RXN +is_a: GO:0018271 ! biotin-protein ligase activity + +[Term] +id: GO:0004079 +name: biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase)." [EC:6.3.4.9] +synonym: "biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity" EXACT [EC:6.3.4.9] +synonym: "biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity" EXACT [EC:6.3.4.9] +synonym: "biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity" EXACT [EC:6.3.4.9] +synonym: "biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity" EXACT [] +synonym: "biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity" EXACT [EC:6.3.4.9] +synonym: "biotin-methylmalonyl-CoA-carboxyltransferase ligase activity" EXACT [EC:6.3.4.9] +synonym: "biotin-methylmalonyl-CoA-carboxyltransferase synthetase" BROAD [EC:6.3.4.9] +synonym: "biotin-methylmalonyl-CoA-carboxytransferase ligase activity" EXACT [EC:6.3.4.9] +synonym: "biotin-methylmalonyl-CoA-carboxytransferase synthetase activity" EXACT [EC:6.3.4.9] +synonym: "biotin-transcarboxylase synthetase activity" EXACT [EC:6.3.4.9] +synonym: "biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)" EXACT [EC:6.3.4.9] +synonym: "biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)" EXACT [EC:6.3.4.9] +synonym: "methylmalonyl coenzyme A holotranscarboxylase synthetase activity" EXACT [EC:6.3.4.9] +xref: EC:6.3.4.9 +xref: MetaCyc:6.3.4.9-RXN +is_a: GO:0018271 ! biotin-protein ligase activity + +[Term] +id: GO:0004080 +name: biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming))." [EC:6.3.4.10] +synonym: "biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity" EXACT [EC:6.3.4.10] +synonym: "biotin-propionyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.10] +synonym: "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity" EXACT [EC:6.3.4.10] +synonym: "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity" EXACT [EC:6.3.4.10] +synonym: "biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.10] +synonym: "holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] +synonym: "propionyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] +synonym: "propionyl-CoA holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] +xref: EC:6.3.4.10 +xref: MetaCyc:6.3.4.10-RXN +is_a: GO:0018271 ! biotin-protein ligase activity + +[Term] +id: GO:0004081 +name: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity +namespace: molecular_function +def: "Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate." [EC:3.6.1.17, PMID:4955726] +synonym: "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.17] +synonym: "Ap(4)A hydrolase activity" BROAD [EC:3.6.1.17] +synonym: "Ap(4)Aase activity" BROAD [EC:3.6.1.17] +synonym: "Ap4A hydrolase activity" BROAD [EC:3.6.1.17] +synonym: "Ap4Aase activity" BROAD [EC:3.6.1.17] +synonym: "bis(5'-adenosyl)-tetraphosphatase activity" NARROW [EC:3.6.1.17] +synonym: "bis(5'-guanosyl)-tetraphosphatase activity" NARROW [EC:3.6.1.17] +synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity" EXACT [EC:3.6.1.17] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity" EXACT [EC:3.6.1.17] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase" NARROW [] +synonym: "diadenosine P1,P4-tetraphosphatase activity" EXACT [EC:3.6.1.17] +synonym: "diadenosinetetraphosphatase (asymmetrical) activity" NARROW [EC:3.6.1.17] +synonym: "diguanosinetetraphosphatase (asymmetrical) activity" NARROW [EC:3.6.1.17] +synonym: "dinucleoside tetraphosphatase activity" EXACT [EC:3.6.1.17] +synonym: "dinucleosidetetraphosphatase (asymmetrical) activity" EXACT [EC:3.6.1.17] +synonym: "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.17] +xref: EC:3.6.1.17 +xref: MetaCyc:3.6.1.17-RXN +xref: Reactome:R-HSA-5696197 "NUDT2 hydrolyses GP4G to GTP, GMP" +xref: RHEA:22484 +is_a: GO:0008796 ! bis(5'-nucleosyl)-tetraphosphatase activity + +[Term] +id: GO:0004082 +name: bisphosphoglycerate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate." [EC:5.4.2.4] +synonym: "2,3-bisphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] +synonym: "2,3-bisphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] +synonym: "2,3-diphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] +synonym: "2,3-diphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] +synonym: "2,3-diphosphoglyceromutase activity" EXACT [EC:5.4.2.4] +synonym: "3-phospho-D-glycerate 1,2-phosphomutase activity" EXACT [EC:5.4.2.4] +synonym: "biphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] +synonym: "bisphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] +synonym: "bisphosphoglyceromutase" BROAD [EC:5.4.2.4] +synonym: "BPGM activity" EXACT [EC:5.4.2.4] +synonym: "diphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] +synonym: "diphosphoglyceric mutase activity" EXACT [EC:5.4.2.4] +synonym: "diphosphoglyceromutase activity" EXACT [EC:5.4.2.4] +synonym: "DPGM" RELATED [EC:5.4.2.4] +synonym: "glycerate phosphomutase activity" EXACT [EC:5.4.2.4] +xref: EC:5.4.2.4 +xref: MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN +xref: Reactome:R-HSA-6798335 "BPGM dimer isomerises 1,3BPG to 2,3BPG" +xref: RHEA:17765 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0004083 +name: bisphosphoglycerate 2-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate." [RHEA:21904] +synonym: "2,3-bisphospho-D-glycerate 2-phosphohydrolase activity" BROAD [] +xref: KEGG_REACTION:R01516 +xref: MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN +xref: RHEA:21904 +is_a: GO:0034416 ! bisphosphoglycerate phosphatase activity + +[Term] +id: GO:0004084 +name: branched-chain-amino-acid transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid." [EC:2.6.1.42, GOC:mah] +synonym: "branched-chain amino acid aminotransferase activity" EXACT [] +synonym: "branched-chain amino acid-glutamate transaminase activity" EXACT [EC:2.6.1.42] +synonym: "branched-chain aminotransferase activity" EXACT [EC:2.6.1.42] +synonym: "branched-chain-amino-acid:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.42] +synonym: "glutamate-branched-chain amino acid transaminase activity" EXACT [EC:2.6.1.42] +synonym: "L-branched chain amino acid aminotransferase activity" EXACT [EC:2.6.1.42] +synonym: "transaminase B activity" RELATED [EC:2.6.1.42] +xref: EC:2.6.1.42 +xref: Reactome:R-HSA-508179 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2]" +xref: Reactome:R-HSA-508189 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1]" +xref: Reactome:R-HSA-70723 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]" +xref: Reactome:R-HSA-70724 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]" +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004085 +name: butyryl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein." [EC:1.3.8.1] +synonym: "3-hydroxyacyl CoA reductase activity" EXACT [EC:1.3.8.1] +synonym: "butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.8.1] +synonym: "butanoyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.8.1] +synonym: "butyryl coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.1] +synonym: "butyryl dehydrogenase activity" EXACT [EC:1.3.8.1] +synonym: "enoyl-coenzyme A reductase activity" EXACT [EC:1.3.8.1] +synonym: "ethylene reductase activity" EXACT [EC:1.3.8.1] +synonym: "short-chain acyl CoA dehydrogenase activity" EXACT [EC:1.3.8.1] +synonym: "short-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.1] +synonym: "short-chain-acyl-CoA dehydrogenase activity" RELATED [EC:1.3.8.1] +synonym: "unsaturated acyl coenzyme A reductase activity" EXACT [EC:1.3.8.1] +synonym: "unsaturated acyl-CoA reductase activity" RELATED [EC:1.3.8.1] +xref: EC:1.3.8.1 +xref: KEGG_REACTION:R01178 +xref: MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN +xref: UM-BBD_reactionID:r0013 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0004086 +name: obsolete carbamoyl-phosphate synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of a reaction that results in the formation of carbamoyl phosphate." [EC:6.3.4.16, EC:6.3.5.5, GOC:mah] +comment: This term was made obsolete because it is a grouping term based on name, rather than on function. +synonym: "carbamoyl phosphate synthase activity" EXACT [] +synonym: "carbamoyl-phosphate synthase activity" EXACT [] +is_obsolete: true +consider: GO:0004087 +consider: GO:0004088 + +[Term] +id: GO:0004087 +name: carbamoyl-phosphate synthase (ammonia) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate." [EC:6.3.4.16, RHEA:10624] +synonym: "carbamoyl phosphate synthase (ammonia) activity" EXACT [] +synonym: "carbamoyl-phosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16] +synonym: "carbamoyl-phosphate synthetase I activity" EXACT [EC:6.3.4.16] +synonym: "carbamoylphosphate synthase (ammonia)" EXACT [EC:6.3.4.16] +synonym: "carbamoylphosphate synthase activity" EXACT [EC:6.3.4.16] +synonym: "carbamoylphosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16] +synonym: "carbamylphosphate synthetase activity" EXACT [EC:6.3.4.16] +synonym: "carbamylphosphate synthetase I" RELATED [EC:6.3.4.16] +synonym: "carbmoylphosphate synthetase activity" EXACT [EC:6.3.4.16] +synonym: "carbon-dioxide--ammonia ligase activity" EXACT [EC:6.3.4.16] +synonym: "carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)" EXACT [EC:6.3.4.16] +synonym: "CPS I activity" NARROW [EC:6.3.4.16] +xref: EC:6.3.4.16 +xref: KEGG_REACTION:R00149 +xref: MetaCyc:6.3.4.16-RXN +xref: Reactome:R-HSA-70555 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]" +xref: RHEA:10624 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004088 +name: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate." [EC:6.3.5.5, RHEA:18633] +synonym: "carbamoyl phosphate synthase (glutamine-hydrolyzing) activity" EXACT [] +synonym: "carbamoyl phosphate synthetase activity" EXACT [EC:6.3.5.5] +synonym: "carbamoyl-phosphate synthase (glutamine-hydrolysing) activity" EXACT [EC:6.3.5.5] +synonym: "carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity" EXACT [EC:6.3.5.5] +synonym: "carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.5] +synonym: "carbamoylphosphate synthetase II activity" EXACT [EC:6.3.5.5] +synonym: "carbamyl phosphate synthetase (glutamine) activity" EXACT [EC:6.3.5.5] +synonym: "carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" EXACT [EC:6.3.5.5] +synonym: "CPS activity" EXACT [EC:6.3.5.5] +synonym: "GD-CPSase activity" EXACT [EC:6.3.5.5] +synonym: "glutamine-dependent carbamoyl-phosphate synthase activity" EXACT [EC:6.3.5.5] +synonym: "glutamine-dependent carbamyl phosphate synthetase activity" EXACT [EC:6.3.5.5] +synonym: "hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" EXACT [EC:6.3.5.5] +xref: EC:6.3.5.5 +xref: MetaCyc:CARBPSYN-RXN +xref: Reactome:R-HSA-73577 "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate" +xref: RHEA:18633 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0004089 +name: carbonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2CO3 = CO2 + H2O." [EC:4.2.1.1] +synonym: "anhydrase activity" EXACT [EC:4.2.1.1] +synonym: "carbonate anhydrase activity" EXACT [EC:4.2.1.1] +synonym: "carbonate hydro-lyase (carbon-dioxide-forming)" EXACT [EC:4.2.1.1] +synonym: "carbonate hydro-lyase activity" EXACT [EC:4.2.1.1] +synonym: "carbonic acid anhydrase activity" EXACT [EC:4.2.1.1] +synonym: "carbonic anhydrase A" RELATED [EC:4.2.1.1] +synonym: "carbonic anhydrase activity" EXACT [] +synonym: "carbonic dehydratase activity" EXACT [EC:4.2.1.1] +synonym: "carboxyanhydrase activity" EXACT [EC:4.2.1.1] +xref: EC:4.2.1.1 +xref: MetaCyc:CARBODEHYDRAT-RXN +xref: Reactome:R-HSA-1237045 "Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton" +xref: Reactome:R-HSA-1237047 "Carbonic anhydrase IV hydrates carbon dioxide to bicarbonate and a proton" +xref: Reactome:R-HSA-1237059 "Carbonic anhydrase IV dehydrates bicarbonate to water and carbon dioxide" +xref: Reactome:R-HSA-1237081 "Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide" +xref: Reactome:R-HSA-1475017 "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)" +xref: Reactome:R-HSA-1475022 "Carbonic anhydrase dehydrates bicarbonate (cytosol)" +xref: Reactome:R-HSA-1475025 "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)" +xref: Reactome:R-HSA-1475026 "Carbonic anhydrase hydrates carbon dioxide (cytosol)" +xref: Reactome:R-HSA-1475028 "Carbonic anhydrase dehydrates bicarbonate (mitochondria)" +xref: Reactome:R-HSA-1475032 "Carbonic anhydrase hydrates carbon dioxide (mitochondria)" +xref: Reactome:R-HSA-1475435 "Carbonic anhydrase I/II hydrates carbon dioxide" +xref: Reactome:R-HSA-1475436 "Carbonic anhydrase I/II dehydrates bicarbonate" +xref: RHEA:10748 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004090 +name: carbonyl reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+." [EC:1.1.1.184] +synonym: "aldehyde reductase 1" RELATED [EC:1.1.1.184] +synonym: "aldehyde reductase I activity" RELATED [EC:1.1.1.184] +synonym: "ALR3" RELATED [EC:1.1.1.184] +synonym: "carbonyl reductase activity" EXACT [EC:1.1.1.184] +synonym: "NADPH-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] +synonym: "NADPH2-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] +synonym: "nonspecific NADPH-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] +synonym: "prostaglandin 9-ketoreductase activity" NARROW [EC:1.1.1.184] +synonym: "secondary-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.184] +synonym: "xenobiotic ketone reductase activity" NARROW [EC:1.1.1.184] +xref: EC:1.1.1.184 +xref: MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN +xref: Reactome:R-HSA-8937419 "CBR3 reduces DOX to DOXOL" +xref: RHEA:19257 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004092 +name: carnitine O-acetyltransferase activity +namespace: molecular_function +alt_id: GO:0004093 +alt_id: GO:0004094 +def: "Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA." [EC:2.3.1.7, RHEA:21136] +synonym: "acetyl-CoA-carnitine O-acetyltransferase activity" EXACT [EC:2.3.1.7] +synonym: "acetyl-CoA:carnitine O-acetyltransferase activity" EXACT [EC:2.3.1.7] +synonym: "acetylcarnitine transferase activity" EXACT [EC:2.3.1.7] +synonym: "carnitine acetyl coenzyme A transferase activity" EXACT [EC:2.3.1.7] +synonym: "carnitine acetylase activity" EXACT [EC:2.3.1.7] +synonym: "carnitine acetyltransferase activity" EXACT [EC:2.3.1.7] +synonym: "carnitine O-acetyltransferase I activity" NARROW [] +synonym: "carnitine O-acetyltransferase II activity" NARROW [] +synonym: "carnitine-acetyl-CoA transferase activity" EXACT [EC:2.3.1.7] +synonym: "CATC" RELATED [EC:2.3.1.7] +xref: EC:2.3.1.7 +xref: KEGG_REACTION:R02396 +xref: MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-390284 "propionyl-CoA + carnitine => propionylcarnitine + CoASH" +xref: Reactome:R-HSA-390291 "acetyl-CoA + carnitine => acetylcarnitine + CoASH" +xref: RHEA:21136 +is_a: GO:0016406 ! carnitine O-acyltransferase activity +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0004095 +name: carnitine O-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine." [EC:2.3.1.21] +synonym: "acylcarnitine transferase activity" EXACT [EC:2.3.1.21] +synonym: "carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] +synonym: "carnitine palmitoyltransferase I" RELATED [EC:2.3.1.21] +synonym: "carnitine palmitoyltransferase II" RELATED [EC:2.3.1.21] +synonym: "carnitine palmitoyltransferase-A" RELATED [EC:2.3.1.21] +synonym: "CPT" RELATED [EC:2.3.1.21] +synonym: "CPT I (outer membrane carnitine palmitoyl transferase)" RELATED [EC:2.3.1.21] +synonym: "CPT-A" RELATED [EC:2.3.1.21] +synonym: "CPT-B" RELATED [EC:2.3.1.21] +synonym: "CPTi" RELATED [EC:2.3.1.21] +synonym: "CPTo" RELATED [EC:2.3.1.21] +synonym: "L-carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] +synonym: "outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] +synonym: "palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity" EXACT [EC:2.3.1.21] +synonym: "palmitoylcarnitine transferase activity" EXACT [EC:2.3.1.21] +xref: EC:2.3.1.21 +xref: MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN +xref: Reactome:R-HSA-200406 "CPT1A,B transfers PALM to CAR" +xref: Reactome:R-HSA-200410 "palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine" +xref: RHEA:12661 +is_a: GO:0016406 ! carnitine O-acyltransferase activity +is_a: GO:0016416 ! O-palmitoyltransferase activity + +[Term] +id: GO:0004096 +name: catalase activity +namespace: molecular_function +alt_id: GO:0016952 +alt_id: GO:0016953 +def: "Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O." [EC:1.11.1.6] +synonym: "bacterial catalase-peroxidase activity" NARROW [] +synonym: "caperase activity" EXACT [EC:1.11.1.6] +synonym: "CAT" RELATED [EC:1.11.1.6] +synonym: "catalase reaction" EXACT [] +synonym: "catalase-peroxidase activity" EXACT [EC:1.11.1.6] +synonym: "equilase activity" EXACT [EC:1.11.1.6] +synonym: "haem catalase activity" NARROW [] +synonym: "heme catalase activity" NARROW [] +synonym: "hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.6] +synonym: "manganese catalase activity" NARROW [] +synonym: "optidase activity" EXACT [EC:1.11.1.6] +xref: EC:1.11.1.6 +xref: MetaCyc:CATAL-RXN +xref: Reactome:R-HSA-1222704 "KatG reduces H2O2" +xref: Reactome:R-HSA-76031 "2 H2O2 => O2 + 2 H2O" +xref: RHEA:20309 +xref: UM-BBD_enzymeID:e0834 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0004097 +name: catechol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O." [EC:1.10.3.1] +comment: GO:0004097 describes oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones. For monooxygenation of monophenols, consider instead the term 'monophenol monooxygenase activity ; GO:0004503'. +synonym: "1,2-benzenediol:oxygen oxidoreductase activity" EXACT [EC:1.10.3.1] +synonym: "catecholase" BROAD [EC:1.10.3.1] +synonym: "diphenol oxidase activity" EXACT [EC:1.10.3.1] +synonym: "dopa oxidase" BROAD [EC:1.10.3.1] +synonym: "o-diphenol oxidoreductase" BROAD [EC:1.10.3.1] +synonym: "o-diphenol:oxygen oxidoreductase" BROAD [EC:1.10.3.1] +synonym: "o-diphenolase activity" EXACT [EC:1.10.3.1] +synonym: "phenolase activity" BROAD [EC:1.10.3.1] +synonym: "polyphenol oxidase activity" EXACT [EC:1.10.3.1] +synonym: "pyrocatechol oxidase" BROAD [EC:1.10.3.1] +synonym: "tyrosinase activity" BROAD [EC:1.10.3.1] +xref: EC:1.10.3.1 +xref: MetaCyc:CATECHOL-OXIDASE-RXN +xref: RHEA:21632 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0004098 +name: cerebroside-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate." [EC:3.1.6.8] +synonym: "arylsulfatase A activity" EXACT [EC:3.1.6.8] +synonym: "cerebroside sulfate sulfatase activity" EXACT [EC:3.1.6.8] +synonym: "cerebroside-3-sulfate 3-sulfohydrolase activity" EXACT [EC:3.1.6.8] +synonym: "cerebroside-sulphatase activity" EXACT [] +xref: EC:3.1.6.8 +xref: MetaCyc:CEREBROSIDE-SULFATASE-RXN +xref: Reactome:R-HSA-1606807 "Arylsulfatase A hydrolyses sulfate from sulfatide to form cerebroside" +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0004099 +name: chitin deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: chitin + H2O = chitosan + acetate." [EC:3.5.1.41] +synonym: "chitin amidohydrolase activity" EXACT [EC:3.5.1.41] +xref: EC:3.5.1.41 +xref: MetaCyc:CHITIN-DEACETYLASE-RXN +xref: RHEA:10464 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0004100 +name: chitin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1)." [EC:2.4.1.16] +synonym: "chitin synthetase activity" EXACT [EC:2.4.1.16] +synonym: "chitin-UDP acetyl-glucosaminyl transferase activity" EXACT [EC:2.4.1.16] +synonym: "chitin-UDP N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.16] +synonym: "chitin-uridine diphosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.16] +synonym: "trans-N-acetylglucosaminosylase activity" EXACT [EC:2.4.1.16] +synonym: "UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity" EXACT [EC:2.4.1.16] +xref: EC:2.4.1.16 +xref: MetaCyc:CHITIN-SYNTHASE-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0004102 +name: choline O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA." [EC:2.3.1.6, RHEA:18821] +synonym: "acetyl-CoA:choline O-acetyltransferase activity" EXACT [EC:2.3.1.6] +synonym: "CHOACTase activity" EXACT [EC:2.3.1.6] +synonym: "choline acetylase activity" EXACT [EC:2.3.1.6] +synonym: "choline acetyltransferase activity" EXACT [EC:2.3.1.6] +xref: EC:2.3.1.6 +xref: KEGG_REACTION:R01023 +xref: MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-264622 "Cho is acetylated to AcCho by CHAT" +xref: RHEA:18821 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0004103 +name: choline kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+)." [EC:2.7.1.32, RHEA:12837] +synonym: "ATP:choline phosphotransferase activity" EXACT [EC:2.7.1.32] +synonym: "choline kinase (phosphorylating)" EXACT [EC:2.7.1.32] +synonym: "choline phosphokinase activity" EXACT [EC:2.7.1.32] +synonym: "choline-ethanolamine kinase activity" EXACT [EC:2.7.1.32] +xref: EC:2.7.1.32 +xref: KEGG_REACTION:R01021 +xref: MetaCyc:CHOLINE-KINASE-RXN +xref: Reactome:R-HSA-1483004 "Cho is phosphorylated to PCho by CHK dimer" +xref: RHEA:12837 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +relationship: part_of GO:0006657 ! CDP-choline pathway + +[Term] +id: GO:0004104 +name: cholinesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion." [EC:3.1.1.8] +subset: goslim_chembl +synonym: "acylcholine acylhydrolase activity" EXACT [EC:3.1.1.8] +synonym: "anticholineesterase activity" EXACT [EC:3.1.1.8] +synonym: "benzoylcholinesterase activity" EXACT [EC:3.1.1.8] +synonym: "BtChoEase activity" EXACT [EC:3.1.1.8] +synonym: "butyrylcholine esterase activity" EXACT [EC:3.1.1.8] +synonym: "butyrylcholinesterase activity" EXACT [EC:3.1.1.8] +synonym: "choline esterase activity" EXACT [EC:3.1.1.8] +synonym: "choline esterase II (unspecific) activity" EXACT [EC:3.1.1.8] +synonym: "non-specific cholinesterase activity" EXACT [EC:3.1.1.8] +synonym: "propionylcholinesterase activity" EXACT [EC:3.1.1.8] +synonym: "pseudocholinesterase activity" EXACT [EC:3.1.1.8] +xref: EC:3.1.1.8 +xref: MetaCyc:CHOLINESTERASE-RXN +xref: RHEA:21964 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004105 +name: choline-phosphate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline." [EC:2.7.7.15] +synonym: "CDP-choline pyrophosphorylase activity" EXACT [EC:2.7.7.15] +synonym: "CDP-choline synthetase activity" EXACT [EC:2.7.7.15] +synonym: "choline phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "CTP-phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "CTP:choline-phosphate cytidylyltransferase activity" EXACT [] +synonym: "CTP:phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "CTP:phosphorylcholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "cytidine diphosphocholine pyrophosphorylase activity" EXACT [EC:2.7.7.15] +synonym: "phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "phosphorylcholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] +synonym: "phosphorylcholine transferase activity" EXACT [EC:2.7.7.15] +synonym: "phosphorylcholine:CTP cytidylyltransferase activity" EXACT [EC:2.7.7.15] +xref: EC:2.7.7.15 +xref: MetaCyc:2.7.7.15-RXN +xref: Reactome:R-HSA-1483081 "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer" +xref: RHEA:18997 +is_a: GO:0070567 ! cytidylyltransferase activity +relationship: part_of GO:0006657 ! CDP-choline pathway + +[Term] +id: GO:0004106 +name: chorismate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: chorismate = prephenate." [EC:5.4.99.5, RHEA:13897] +synonym: "chorismate pyruvatemutase activity" EXACT [EC:5.4.99.5] +synonym: "hydroxyphenylpyruvate synthase activity" BROAD [EC:5.4.99.5] +xref: EC:5.4.99.5 +xref: KEGG_REACTION:R01715 +xref: MetaCyc:CHORISMATEMUT-RXN +xref: RHEA:13897 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0004107 +name: chorismate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate." [EC:4.2.3.5, RHEA:21020] +synonym: "5-enolpyruvylshikimate-3-phosphate phospholyase activity" EXACT [EC:4.2.3.5] +synonym: "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)" EXACT [EC:4.2.3.5] +synonym: "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity" EXACT [EC:4.2.3.5] +xref: EC:4.2.3.5 +xref: KEGG_REACTION:R01714 +xref: MetaCyc:CHORISMATE-SYNTHASE-RXN +xref: RHEA:21020 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0004108 +name: citrate (Si)-synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." [EC:2.3.3.1, ISBN:0121227073] +comment: Note that this function was formerly EC:4.1.3.7. +synonym: "(R)-citric synthase activity" EXACT [EC:2.3.3.1] +synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]" RELATED [EC:2.3.3.1] +synonym: "citrate condensing enzyme activity" EXACT [EC:2.3.3.1] +synonym: "citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.1] +synonym: "citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)" EXACT [EC:2.3.3.1] +synonym: "citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]" RELATED [EC:2.3.3.1] +synonym: "citrate oxaloacetate-lyase, CoA-acetylating activity" EXACT [EC:2.3.3.1] +synonym: "citrate synthase activity" BROAD [EC:2.3.3.1] +synonym: "citrate synthetase activity" EXACT [EC:2.3.3.1] +synonym: "citric synthase activity" EXACT [EC:2.3.3.1] +synonym: "citric-condensing enzyme activity" EXACT [EC:2.3.3.1] +synonym: "citrogenase activity" EXACT [EC:2.3.3.1] +synonym: "condensing enzyme activity" BROAD [EC:2.3.3.1] +synonym: "oxalacetic transacetase activity" EXACT [EC:2.3.3.1] +synonym: "oxaloacetate transacetase activity" EXACT [EC:2.3.3.1] +xref: EC:2.3.3.1 +xref: MetaCyc:CITSYN-RXN +xref: Reactome:R-HSA-70975 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA" +is_a: GO:0036440 ! citrate synthase activity + +[Term] +id: GO:0004109 +name: coproporphyrinogen oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX." [EC:1.3.3.3, RHEA:18257] +synonym: "coprogen oxidase activity" EXACT [] +synonym: "coproporphyrinogen-III oxidase activity" EXACT [] +synonym: "coproporphyrinogen:oxygen oxidoreductase (decarboxylating)" EXACT [EC:1.3.3.3] +synonym: "coproporphyrinogenase activity" EXACT [] +xref: EC:1.3.3.3 +xref: KEGG_REACTION:R03220 +xref: MetaCyc:RXN0-1461 +xref: Reactome:R-HSA-189421 "CPO transforms COPRO3 to PPGEN9" +xref: RHEA:18257 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0004110 +name: corticosteroid side-chain-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al." [EC:5.3.1.21, RHEA:17861] +synonym: "11-deoxycorticosterone aldose-ketose-isomerase activity" EXACT [EC:5.3.1.21] +synonym: "11-deoxycorticosterone ketol-isomerase activity" EXACT [EC:5.3.1.21] +xref: EC:5.3.1.21 +xref: KEGG_REACTION:R04165 +xref: MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN +xref: RHEA:17861 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004111 +name: creatine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+)." [EC:2.7.3.2, RHEA:17157] +synonym: "adenosine triphosphate-creatine transphosphorylase activity" EXACT [EC:2.7.3.2] +synonym: "ATP:creatine N-phosphotransferase activity" EXACT [EC:2.7.3.2] +synonym: "ATP:creatine phosphotransferase activity" EXACT [EC:2.7.3.2] +synonym: "BB-CK" RELATED [EC:2.7.3.2] +synonym: "CK" RELATED [EC:2.7.3.2] +synonym: "CK-BB" RELATED [EC:2.7.3.2] +synonym: "CK-MB" RELATED [EC:2.7.3.2] +synonym: "CK-MM" RELATED [EC:2.7.3.2] +synonym: "CKMiMi" RELATED [EC:2.7.3.2] +synonym: "creatine phosphokinase activity" EXACT [EC:2.7.3.2] +synonym: "creatine phosphotransferase activity" EXACT [EC:2.7.3.2] +synonym: "MB-CK" RELATED [EC:2.7.3.2] +synonym: "Mi-CK" RELATED [EC:2.7.3.2] +synonym: "MiMi-CK" RELATED [EC:2.7.3.2] +synonym: "MM-CK" RELATED [EC:2.7.3.2] +synonym: "phosphocreatine kinase activity" EXACT [EC:2.7.3.2] +xref: EC:2.7.3.2 +xref: KEGG_REACTION:R01881 +xref: MetaCyc:CREATINE-KINASE-RXN +xref: Reactome:R-HSA-200318 "creatine + ATP => phosphocreatine + ADP [CKB,CKM]" +xref: Reactome:R-HSA-200326 "creatine + ATP => phosphocreatine + ADP [CK octamer]" +xref: RHEA:17157 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0004112 +name: cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate." [GOC:mah] +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0004113 +name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate." [EC:3.1.4.37] +synonym: "2',3'-cyclic AMP phosphodiesterase activity" EXACT [EC:3.1.4.37] +synonym: "2',3'-cyclic nucleoside monophosphate phosphodiesterase" BROAD [EC:3.1.4.37] +synonym: "2',3'-cyclic nucleotide 3'-phosphodiesterase activity" EXACT [] +synonym: "2',3'-cyclic nucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.4.37] +synonym: "2',3'-cyclic nucleotide phosphohydrolase" BROAD [EC:3.1.4.37] +synonym: "2':3'-CNMP-3'-ase activity" EXACT [EC:3.1.4.37] +synonym: "2':3'-cyclic nucleotide 3'-phosphodiesterase activity" EXACT [EC:3.1.4.37] +synonym: "CNPase activity" EXACT [EC:3.1.4.37] +synonym: "cyclic 2',3'-nucleotide 3'-phosphodiesterase activity" EXACT [EC:3.1.4.37] +synonym: "cyclic 2',3'-nucleotide phosphodiesterase" BROAD [EC:3.1.4.37] +synonym: "cyclic-CMP phosphodiesterase activity" NARROW [EC:3.1.4.37] +synonym: "nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity" EXACT [EC:3.1.4.37] +xref: EC:3.1.4.37 +xref: MetaCyc:3.1.4.37-RXN +is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004114 +name: 3',5'-cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate." [EC:3.1.4.17] +synonym: "3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "3',5' cyclic-nucleotide phosphodiesterase activity" EXACT [] +synonym: "3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.17] +synonym: "3',5'-cyclonucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "3',5'-nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity" EXACT [EC:3.1.4.17] +synonym: "3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.17] +synonym: "cyclic 3',5'-mononucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "cyclic 3',5'-nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "cyclic 3',5'-phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "cyclic 3',5-nucleotide monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "cyclic AMP phosphodiesterase activity" NARROW [EC:3.1.4.17] +synonym: "cyclic nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity" EXACT [EC:3.1.4.17] +synonym: "nucleoside 3',5'-cyclic phosphate diesterase activity" EXACT [EC:3.1.4.17] +synonym: "nucleoside-3',5-monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] +synonym: "PDE" RELATED [EC:3.1.4.17] +xref: EC:3.1.4.17 +xref: MetaCyc:3.1.4.17-RXN +xref: Reactome:R-HSA-162425 "p-S295-PDE3B hydrolyses cAMP to AMP" +xref: RHEA:14653 +is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004115 +name: 3',5'-cyclic-AMP phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate." [GOC:ai] +synonym: "3',5' cAMP-specific phosphodiesterase activity" EXACT [] +synonym: "3',5'-cAMP-specific phosphodiesterase activity" EXACT [] +synonym: "3',5'-cyclic-AMP-specific phosphodiesterase activity" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity" EXACT [] +synonym: "cAMP-specific phosphodiesterase activity" EXACT [] +synonym: "cyclic AMP-specific phosphodiesterase activity" EXACT [] +xref: EC:3.1.4 +xref: MetaCyc:RXN0-5038 +xref: Reactome:R-HSA-111962 "cAMP hydrolysis by PDE 4" +xref: Reactome:R-HSA-418553 "cAMP degradation by Phosphodiesterases" +xref: Reactome:R-HSA-9629675 "PDE3A,3B hydrolyses cAMP to AMP" +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004117 +name: calmodulin-dependent cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin." [GOC:mah] +xref: EC:3.1.4 +xref: Reactome:R-HSA-111955 "cAMP hydrolysis by Cam-PDE 1" +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004118 +name: cGMP-stimulated cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP." [GOC:mah] +xref: EC:3.1.4 +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004119 +name: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP." [GOC:mah] +xref: EC:3.1.4 +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004120 +name: photoreceptor cyclic-nucleotide phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide." [EC:3.1.4.-] +xref: EC:3.1.4 +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0004121 +name: cystathionine beta-lyase activity +namespace: molecular_function +alt_id: GO:0008799 +def: "Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate." [EC:4.4.1.8] +synonym: "beta C-S lyase activity" EXACT [EC:4.4.1.8] +synonym: "beta-cystathionase activity" EXACT [EC:4.4.1.8] +synonym: "cystathionine L-homocysteine-lyase (deaminating)" EXACT [EC:4.4.1.8] +synonym: "cystine lyase activity" EXACT [EC:4.4.1.8] +synonym: "L-cystathionine L-homocysteine-lyase (deaminating)" EXACT [EC:4.4.1.8] +synonym: "L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.8] +xref: EC:4.4.1.8 +xref: MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN +xref: RHEA:13965 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0004122 +name: cystathionine beta-synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O." [EC:4.2.1.22] +synonym: "beta-thionase activity" EXACT [EC:4.2.1.22] +synonym: "L-serine hydro-lyase (adding homocysteine)" EXACT [EC:4.2.1.22] +synonym: "L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [EC:4.2.1.22] +synonym: "methylcysteine synthase activity" EXACT [EC:4.2.1.22] +synonym: "serine sulfhydrase activity" EXACT [EC:4.2.1.22] +synonym: "serine sulfhydrylase activity" EXACT [EC:4.2.1.22] +xref: EC:4.2.1.22 +xref: MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN +xref: Reactome:R-HSA-1614524 "Cystathionine is formed from homocysteine and serine" +xref: RHEA:10112 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004123 +name: cystathionine gamma-lyase activity +namespace: molecular_function +alt_id: GO:0016225 +def: "Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+." [RHEA:14005] +synonym: "gamma-cystathionase activity" BROAD [EC:4.4.1.1] +synonym: "homoserine deaminase activity" RELATED [EC:4.4.1.1] +synonym: "homoserine deaminase-cystathionase activity" RELATED [EC:4.4.1.1] +synonym: "homoserine dehydratase activity" RELATED [EC:4.4.1.1] +synonym: "L-cystathionine cysteine-lyase (deaminating)" BROAD [EC:4.4.1.1] +synonym: "L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.1] +xref: EC:4.4.1.1 +xref: KEGG_REACTION:R01001 +xref: MetaCyc:CYSTAGLY-RXN +xref: Reactome:R-HSA-1614583 "Cleavage of cystathionine into cysteine" +xref: RHEA:14005 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0004124 +name: cysteine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate." [EC:2.5.1.47] +comment: Note that this function was formerly 4.2.99.8. +synonym: "3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.47] +synonym: "acetylserine sulfhydrylase activity" EXACT [EC:2.5.1.47] +synonym: "cysteine synthetase activity" EXACT [EC:2.5.1.47] +synonym: "O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity" EXACT [EC:2.5.1.47] +synonym: "O-acetyl-L-serine sulfhydrylase activity" EXACT [EC:2.5.1.47] +synonym: "O-acetyl-L-serine sulfohydrolase activity" EXACT [EC:2.5.1.47] +synonym: "O-acetylserine (thiol)-lyase A activity" NARROW [EC:2.5.1.47] +synonym: "O-acetylserine (thiol)-lyase activity" EXACT [EC:2.5.1.47] +synonym: "O-acetylserine sulfhydrylase activity" EXACT [EC:2.5.1.47] +synonym: "O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)" EXACT [EC:2.5.1.47] +synonym: "O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.47] +synonym: "OAS sulfhydrylase activity" EXACT [EC:2.5.1.47] +xref: EC:2.5.1.47 +xref: MetaCyc:ACSERLY-RXN +xref: RHEA:14829 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +relationship: part_of GO:0019344 ! cysteine biosynthetic process + +[Term] +id: GO:0004125 +name: L-seryl-tRNASec selenium transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate." [EC:2.9.1.1] +synonym: "cysteinyl-tRNA(Sec)-selenium transferase activity" EXACT [EC:2.9.1.1] +synonym: "cysteinyl-tRNA(Sel)-selenium transferase activity" EXACT [EC:2.9.1.1] +synonym: "cysteinyl-tRNA(Ser) selenium transferase activity" EXACT [] +synonym: "cysteinyl-tRNASec-selenium transferase activity" EXACT [EC:2.9.1.1] +synonym: "cysteinyl-tRNASel-selenium transferase activity" EXACT [EC:2.9.1.1] +synonym: "L-selenocysteinyl-tRNA(Sec) synthase activity" EXACT [EC:2.9.1.1] +synonym: "L-selenocysteinyl-tRNA(Sel) synthase activity" EXACT [EC:2.9.1.1] +synonym: "L-selenocysteinyl-tRNASec synthase activity" EXACT [EC:2.9.1.1] +synonym: "L-selenocysteinyl-tRNASel synthase activity" EXACT [EC:2.9.1.1] +synonym: "L-seryl-tRNA(Ser) selenium transferase activity" EXACT [] +synonym: "selenocysteine synthase activity" EXACT [] +synonym: "selenocysteinyl-tRNA(Ser) synthase activity" EXACT [] +synonym: "selenophosphate:L-seryl-tRNASec selenium transferase activity" EXACT [EC:2.9.1.1] +xref: EC:2.9.1.1 +xref: MetaCyc:2.9.1.1-RXN +is_a: GO:0016785 ! transferase activity, transferring selenium-containing groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0004126 +name: cytidine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytidine + H2O = uridine + NH3." [EC:3.5.4.5] +synonym: "cytidine aminohydrolase activity" EXACT [EC:3.5.4.5] +synonym: "cytosine nucleoside deaminase activity" EXACT [EC:3.5.4.5] +xref: EC:3.5.4.5 +xref: MetaCyc:CYTIDEAM2-RXN +xref: Reactome:R-HSA-73608 "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)" +xref: Reactome:R-HSA-83677 "C4 deamination of cytidine" +xref: RHEA:16069 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity +relationship: part_of GO:0009972 ! cytidine deamination + +[Term] +id: GO:0004127 +name: cytidylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP." [EC:2.7.4.14] +synonym: "ATP:CMP phosphotransferase activity" EXACT [EC:2.7.4.14] +synonym: "ATP:UMP-CMP phosphotransferase activity" EXACT [EC:2.7.4.14] +synonym: "CMP kinase activity" NARROW [EC:2.7.4.14] +synonym: "CTP:CMP phosphotransferase activity" EXACT [EC:2.7.4.14] +synonym: "cytidine monophosphate kinase activity" EXACT [EC:2.7.4.14] +synonym: "dCMP kinase activity" NARROW [EC:2.7.4.14] +synonym: "deoxycytidine monophosphokinase activity" EXACT [EC:2.7.4.14] +synonym: "deoxycytidylate kinase activity" BROAD [EC:2.7.4.14] +synonym: "pyrimidine nucleoside monophosphate kinase activity" EXACT [EC:2.7.4.14] +synonym: "UMP-CMP kinase activity" EXACT [EC:2.7.4.14] +xref: EC:2.7.4.14 +xref: MetaCyc:CMPKI-RXN +is_a: GO:0050145 ! nucleoside monophosphate kinase activity + +[Term] +id: GO:0004128 +name: cytochrome-b5 reductase activity, acting on NAD(P)H +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5)." [EC:1.6.2.2, ISBN:0198547684] +synonym: "cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] +synonym: "dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] +synonym: "NADH 5alpha-reductase activity" EXACT [EC:1.6.2.2] +synonym: "NADH-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] +synonym: "NADH-cytochrome-b5 reductase activity" EXACT [EC:1.6.2.2] +synonym: "NADH-ferricytochrome b5 oxidoreductase activity" EXACT [EC:1.6.2.2] +synonym: "NADH:ferricytochrome-b5 oxidoreductase activity" EXACT [EC:1.6.2.2] +synonym: "reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] +xref: EC:1.6.2.2 +xref: MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN +xref: Reactome:R-HSA-198824 "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme" +xref: Reactome:R-HSA-6806831 "CYB5Rs reduce MetHb to HbA" +is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor + +[Term] +id: GO:0004129 +name: cytochrome-c oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] +comment: The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. +synonym: "aa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] +synonym: "ba3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] +synonym: "caa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] +synonym: "cbb3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] +synonym: "complex IV (mitochondrial electron transport) activity" RELATED [EC:1.9.3.1] +synonym: "cytochrome a3 activity" NARROW [EC:1.9.3.1] +synonym: "cytochrome aa3 activity" NARROW [EC:1.9.3.1] +synonym: "cytochrome c oxidase activity" EXACT [GOC:tb] +synonym: "cytochrome oxidase activity" RELATED [EC:1.9.3.1] +synonym: "ferrocytochrome c oxidase" NARROW [EC:1.9.3.1] +synonym: "ferrocytochrome-c:oxygen oxidoreductase" NARROW [EC:1.9.3.1] +synonym: "indophenol oxidase" NARROW [EC:1.9.3.1] +synonym: "indophenolase" NARROW [EC:1.9.3.1] +synonym: "NADH cytochrome c oxidase" EXACT [EC:1.9.3.1] +synonym: "warburg's respiratory enzyme activity" RELATED [EC:1.9.3.1] +xref: EC:1.9.3.1 +xref: MetaCyc:CYTOCHROME-C-OXIDASE-RXN +xref: Reactome:R-HSA-163214 "Electron transfer from reduced cytochrome c to molecular oxygen" +is_a: GO:0009055 ! electron transfer activity +is_a: GO:0015002 ! heme-copper terminal oxidase activity +is_a: GO:0015078 ! proton transmembrane transporter activity +is_a: GO:0016676 ! oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor + +[Term] +id: GO:0004130 +name: cytochrome-c peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O." [EC:1.11.1.5] +synonym: "apocytochrome c peroxidase activity" EXACT [EC:1.11.1.5] +synonym: "cytochrome c peroxidase activity" EXACT [EC:1.11.1.5] +synonym: "cytochrome c-551 peroxidase activity" EXACT [EC:1.11.1.5] +synonym: "cytochrome c-H2O oxidoreductase activity" EXACT [EC:1.11.1.5] +synonym: "cytochrome peroxidase activity" EXACT [EC:1.11.1.5] +synonym: "ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.5] +synonym: "mesocytochrome c peroxidase azide" RELATED [EC:1.11.1.5] +synonym: "mesocytochrome c peroxidase cyanate" RELATED [EC:1.11.1.5] +synonym: "mesocytochrome c peroxidase cyanide" RELATED [EC:1.11.1.5] +xref: EC:1.11.1.5 +xref: MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0004131 +name: cytosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytosine + H2O = uracil + NH3." [EC:3.5.4.1] +synonym: "cytosine aminohydrolase activity" EXACT [EC:3.5.4.1] +synonym: "isocytosine deaminase activity" EXACT [EC:3.5.4.1] +xref: EC:3.5.4.1 +xref: MetaCyc:CYTDEAM-RXN +xref: RHEA:20605 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0004132 +name: dCMP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCMP + H2O = dUMP + NH3." [EC:3.5.4.12] +synonym: "dCMP aminohydrolase activity" EXACT [EC:3.5.4.12] +synonym: "deoxy-CMP-deaminase activity" EXACT [EC:3.5.4.12] +synonym: "deoxycytidine monophosphate deaminase activity" EXACT [EC:3.5.4.12] +synonym: "deoxycytidine-5'-monophosphate aminohydrolase activity" EXACT [EC:3.5.4.12] +synonym: "deoxycytidine-5'-phosphate deaminase activity" EXACT [EC:3.5.4.12] +synonym: "deoxycytidylate aminohydrolase activity" EXACT [EC:3.5.4.12] +synonym: "deoxycytidylate deaminase activity" EXACT [EC:3.5.4.12] +xref: EC:3.5.4.12 +xref: MetaCyc:DCMP-DEAMINASE-RXN +xref: Reactome:R-HSA-73596 "dCMP + H2O => dUMP + NH4+" +xref: RHEA:22924 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0004133 +name: glycogen debranching enzyme activity +namespace: molecular_function +def: "Catalysis of the cleavage of branch points in branched glycogen polymers." [ISBN:0198506732] +subset: goslim_pir +is_a: GO:0003824 ! catalytic activity +relationship: part_of GO:0005977 ! glycogen metabolic process + +[Term] +id: GO:0004134 +name: 4-alpha-glucanotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan." [EC:2.4.1.25] +synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity" EXACT [EC:2.4.1.25] +synonym: "amylomaltase activity" EXACT [EC:2.4.1.25] +synonym: "D-enzyme activity" RELATED [EC:2.4.1.25] +synonym: "debranching enzyme maltodextrin glycosyltransferase activity" EXACT [EC:2.4.1.25] +synonym: "dextrin glycosyltransferase activity" RELATED [EC:2.4.1.25] +synonym: "dextrin transglycosylase activity" EXACT [EC:2.4.1.25] +synonym: "disproportionating enzyme activity" RELATED [EC:2.4.1.25] +synonym: "oligo-1,4-1,4-glucantransferase activity" EXACT [EC:2.4.1.25] +xref: EC:2.4.1.25 +xref: MetaCyc:AMYLOMALT-RXN +xref: MetaCyc:RXN-1828 +xref: MetaCyc:RXN-9023 +xref: Reactome:R-HSA-71552 "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin" +is_a: GO:0004133 ! glycogen debranching enzyme activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0004135 +name: amylo-alpha-1,6-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present." [EC:3.2.1.33, ISBN:0198506732] +synonym: "amylo-1,6-glucosidase activity" EXACT [] +synonym: "amylopectin 1,6-glucosidase activity" EXACT [EC:3.2.1.33] +synonym: "dextrin 6-alpha-D-glucosidase activity" RELATED [EC:3.2.1.33] +synonym: "dextrin-1,6-glucosidase activity" EXACT [EC:3.2.1.33] +synonym: "glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity" EXACT [EC:3.2.1.33] +xref: EC:3.2.1.33 +xref: MetaCyc:3.2.1.33-RXN +xref: Reactome:R-HSA-71593 "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose" +is_a: GO:0004133 ! glycogen debranching enzyme activity +is_a: GO:0090599 ! alpha-glucosidase activity + +[Term] +id: GO:0004136 +name: deoxyadenosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+)." [EC:2.7.1.76, RHEA:23452] +synonym: "ATP:deoxyadenosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.76] +synonym: "deoxyadenosine kinase (phosphorylating)" EXACT [EC:2.7.1.76] +synonym: "purine-deoxyribonucleoside kinase activity" EXACT [EC:2.7.1.76] +xref: EC:2.7.1.76 +xref: KEGG_REACTION:R02089 +xref: MetaCyc:DEOXYADENOSINE-KINASE-RXN +xref: RHEA:23452 +is_a: GO:0019136 ! deoxynucleoside kinase activity +relationship: part_of GO:0006170 ! dAMP biosynthetic process + +[Term] +id: GO:0004137 +name: deoxycytidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP." [EC:2.7.1.74] +synonym: "2'-deoxycytidine kinase activity" EXACT [EC:2.7.1.74] +synonym: "Ara-C kinase activity" EXACT [EC:2.7.1.74] +synonym: "arabinofuranosylcytosine kinase activity" EXACT [EC:2.7.1.74] +synonym: "deoxycytidine kinase (phosphorylating)" EXACT [EC:2.7.1.74] +synonym: "deoxycytidine-cytidine kinase activity" EXACT [EC:2.7.1.74] +synonym: "NTP:deoxycytidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.74] +xref: EC:2.7.1.74 +xref: MetaCyc:DEOXYCYTIDINE-KINASE-RXN +xref: RHEA:20061 +is_a: GO:0019136 ! deoxynucleoside kinase activity + +[Term] +id: GO:0004138 +name: deoxyguanosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+)." [EC:2.7.1.113, RHEA:19201] +synonym: "(dihydroxypropoxymethyl)guanine kinase activity" EXACT [EC:2.7.1.113] +synonym: "2'-deoxyguanosine kinase activity" EXACT [EC:2.7.1.113] +synonym: "ATP:deoxyguanosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.113] +synonym: "deoxyguanosine kinase (phosphorylating)" EXACT [EC:2.7.1.113] +synonym: "NTP-deoxyguanosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.113] +xref: EC:2.7.1.113 +xref: KEGG_REACTION:R01967 +xref: MetaCyc:DEOXYGUANOSINE-KINASE-RXN +xref: RHEA:19201 +is_a: GO:0019136 ! deoxynucleoside kinase activity + +[Term] +id: GO:0004139 +name: deoxyribose-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde." [EC:4.1.2.4, RHEA:12821] +synonym: "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)" EXACT [EC:4.1.2.4] +synonym: "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity" EXACT [EC:4.1.2.4] +synonym: "2-deoxyribose-5-phosphate aldolase activity" EXACT [EC:4.1.2.4] +synonym: "deoxyriboaldolase activity" RELATED [EC:4.1.2.4] +synonym: "deoxyribose-5-phosphate aldolase activity" EXACT [EC:4.1.2.4] +synonym: "phosphodeoxyriboaldolase activity" EXACT [EC:4.1.2.4] +xref: EC:4.1.2.4 +xref: KEGG_REACTION:R01066 +xref: MetaCyc:DEOXYRIBOSE-P-ALD-RXN +xref: Reactome:R-HSA-6787321 "DERA cleaves dR5P to GA3P and CH3CHO" +xref: RHEA:12821 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0004140 +name: dephospho-CoA kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+)." [EC:2.7.1.24, RHEA:18245] +synonym: "3'-dephospho-CoA kinase activity" EXACT [EC:2.7.1.24] +synonym: "ATP:dephospho-CoA 3'-phosphotransferase activity" EXACT [EC:2.7.1.24] +synonym: "dephosphocoenzyme A kinase (phosphorylating)" EXACT [EC:2.7.1.24] +synonym: "dephosphocoenzyme A kinase activity" RELATED [EC:2.7.1.24] +xref: EC:2.7.1.24 +xref: KEGG_REACTION:R00130 +xref: MetaCyc:DEPHOSPHOCOAKIN-RXN +xref: Reactome:R-HSA-196773 "COASY phosphorylates DP-CoA" +xref: RHEA:18245 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004141 +name: dethiobiotin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate." [EC:6.3.3.3, RHEA:15805] +synonym: "7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.3] +synonym: "desthiobiotin synthase activity" EXACT [EC:6.3.3.3] +synonym: "DTB synthetase activity" EXACT [EC:6.3.3.3] +xref: EC:6.3.3.3 +xref: KEGG_REACTION:R03182 +xref: MetaCyc:DETHIOBIOTIN-SYN-RXN +xref: RHEA:15805 +is_a: GO:0016882 ! cyclo-ligase activity + +[Term] +id: GO:0004142 +name: diacylglycerol cholinephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine." [EC:2.7.8.2, RHEA:32939] +synonym: "1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "1-alkyl-2-acetylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "alkylacylglycerol choline phosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "alkylacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "CDP-choline diglyceride phosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "cholinephosphotransferase activity" RELATED [EC:2.7.8.2] +synonym: "CPT" RELATED [EC:2.7.8.2] +synonym: "cytidine diphosphocholine glyceride transferase activity" EXACT [EC:2.7.8.2] +synonym: "cytidine diphosphorylcholine diglyceride transferase activity" EXACT [EC:2.7.8.2] +synonym: "diacylglycerol choline phosphotransferase activity" EXACT [EC:2.7.8.2] +synonym: "phosphocholine diacylglyceroltransferase activity" EXACT [EC:2.7.8.2] +synonym: "phosphorylcholine--glyceride transferase activity" EXACT [EC:2.7.8.2] +synonym: "sn-1,2-diacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] +xref: EC:2.7.8.2 +xref: MetaCyc:RXN-5781 +xref: Reactome:R-HSA-1482961 "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane" +xref: Reactome:R-HSA-1482973 "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane" +xref: RHEA:32939 +is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity +relationship: part_of GO:0006657 ! CDP-choline pathway + +[Term] +id: GO:0004143 +name: diacylglycerol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate." [EC:2.7.1.107, GOC:elh] +synonym: "1,2-diacylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.107] +synonym: "1,2-diacylglycerol kinase activity" EXACT [EC:2.7.1.107] +synonym: "arachidonoyl-specific diacylglycerol kinase activity" EXACT [EC:2.7.1.107] +synonym: "ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [EC:2.7.1.107] +synonym: "ATP:diacylglycerol phosphotransferase activity" NARROW [EC:2.7.1.107] +synonym: "CTP:diacylglycerol kinase activity" NARROW [] +synonym: "DG kinase activity" EXACT [EC:2.7.1.107] +synonym: "DGK activity" EXACT [EC:2.7.1.107] +synonym: "diacylglycerol:ATP kinase activity" NARROW [EC:2.7.1.107] +synonym: "diglyceride kinase activity" EXACT [EC:2.7.1.107] +synonym: "sn-1,2-diacylglycerol kinase activity" EXACT [EC:2.7.1.107] +xref: EC:2.7.1.107 +xref: MetaCyc:DIACYLGLYKIN-RXN +xref: Reactome:R-HSA-426240 "DAG kinase produces phosphatidic acid from DAG" +xref: RHEA:10272 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004144 +name: diacylglycerol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol." [EC:2.3.1.20] +synonym: "1,2-diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] +synonym: "acyl-CoA:1,2-diacylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.20] +synonym: "diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] +synonym: "diglyceride acyltransferase activity" EXACT [EC:2.3.1.20] +synonym: "diglyceride O-acyltransferase activity" EXACT [EC:2.3.1.20] +synonym: "palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] +xref: EC:2.3.1.20 +xref: MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-1482889 "DAG is acylated to TAG by DGAT1/2" +xref: Reactome:R-HSA-549192 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]" +xref: Reactome:R-HSA-75900 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]" +xref: Reactome:R-HSA-8848580 "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG" +xref: RHEA:10868 +is_a: GO:0016411 ! acylglycerol O-acyltransferase activity + +[Term] +id: GO:0004145 +name: diamine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine." [EC:2.3.1.57] +synonym: "acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity" EXACT [EC:2.3.1.57] +synonym: "acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity" NARROW [] +synonym: "diamine acetyltransferase activity" EXACT [] +synonym: "putrescine (diamine)-acetylating enzyme activity" NARROW [] +synonym: "putrescine acetylase activity" NARROW [EC:2.3.1.57] +synonym: "putrescine acetyltransferase activity" NARROW [EC:2.3.1.57] +synonym: "putrescine N-acetyltransferase activity" NARROW [EC:2.3.1.57] +synonym: "spermidine acetyltransferase activity" NARROW [EC:2.3.1.57] +synonym: "spermidine N(1)-acetyltransferase activity" NARROW [EC:2.3.1.57] +synonym: "spermidine N1-acetyltransferase activity" EXACT [EC:2.3.1.57] +synonym: "spermidine/spermine N1-acetyltransferase activity" EXACT [EC:2.3.1.57] +synonym: "spermine acetyltransferase" NARROW [] +synonym: "spermine N(1)-acetyltransferase" NARROW [] +synonym: "spermine N-acetyltransferase" RELATED [] +xref: EC:2.3.1.57 +xref: MetaCyc:DIAMACTRANS-RXN +xref: Reactome:R-HSA-351207 "Spermine => N-acetylated spermine" +xref: Reactome:R-HSA-351208 "Spermidine => N-acetylated spermidine" +xref: RHEA:25181 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004146 +name: dihydrofolate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+." [EC:1.5.1.3] +synonym: "5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.3] +synonym: "7,8-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] +synonym: "DHFR" RELATED [EC:1.5.1.3] +synonym: "dihydrofolate reductase:thymidylate synthase activity" EXACT [EC:1.5.1.3] +synonym: "dihydrofolate reduction" EXACT [] +synonym: "dihydrofolic acid reductase activity" EXACT [EC:1.5.1.3] +synonym: "dihydrofolic reductase activity" EXACT [EC:1.5.1.3] +synonym: "folic acid reductase activity" EXACT [EC:1.5.1.3] +synonym: "folic reductase activity" EXACT [EC:1.5.1.3] +synonym: "NADPH-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] +synonym: "pteridine reductase:dihydrofolate reductase activity" EXACT [EC:1.5.1.3] +synonym: "tetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.3] +synonym: "thymidylate synthetase-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] +xref: EC:1.5.1.3 +xref: MetaCyc:DIHYDROFOLATEREDUCT-RXN +xref: Reactome:R-HSA-1497794 "Salvage - BH2 is reduced to BH4 by DHFR" +xref: RHEA:15009 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004147 +name: dihydrolipoamide branched chain acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain." [GOC:mah] +synonym: "dihydrolipoamide branched chain transacylase activity" EXACT [] +is_a: GO:0030523 ! dihydrolipoamide S-acyltransferase activity + +[Term] +id: GO:0004148 +name: dihydrolipoyl dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+." [EC:1.8.1.4] +synonym: "dehydrolipoate dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "diaphorase activity" EXACT [EC:1.8.1.4] +synonym: "dihydrolipoamide dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "dihydrolipoamide reduction" RELATED [EC:1.8.1.4] +synonym: "dihydrolipoamide:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] +synonym: "dihydrolipoic dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "dihydrolipoylprotein reduction" RELATED [EC:1.8.1.4] +synonym: "dihydrothioctic dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "E3 component of alpha-ketoacid dehydrogenase complexes activity" RELATED [EC:1.8.1.4] +synonym: "glycine-cleavage system L-protein activity" RELATED [EC:1.8.1.4] +synonym: "L-protein activity" RELATED [EC:1.8.1.4] +synonym: "LDP-Glc activity" NARROW [EC:1.8.1.4] +synonym: "LDP-Val activity" NARROW [EC:1.8.1.4] +synonym: "lipoamide dehydrogenase (NADH) activity" EXACT [EC:1.8.1.4] +synonym: "lipoamide oxidoreductase (NADH) activity" EXACT [EC:1.8.1.4] +synonym: "lipoamide reductase (NADH) activity" EXACT [EC:1.8.1.4] +synonym: "lipoamide reductase activity" EXACT [EC:1.8.1.4] +synonym: "lipoate dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "lipoic acid dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "lipoyl dehydrogenase activity" EXACT [EC:1.8.1.4] +synonym: "protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] +synonym: "protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] +xref: EC:1.8.1.4 +xref: MetaCyc:DIHYDLIPOXN-RXN +xref: Reactome:R-HSA-1222412 "lpdC dimer reactivates dlaT" +xref: Reactome:R-HSA-5694018 "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate" +xref: RHEA:15045 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0004149 +name: dihydrolipoyllysine-residue succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide." [EC:2.3.1.61] +synonym: "dihydrolipoamide S-succinyltransferase activity" EXACT [] +synonym: "dihydrolipoamide succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "dihydrolipoic transsuccinylase activity" EXACT [EC:2.3.1.61] +synonym: "dihydrolipolyl transsuccinylase activity" EXACT [EC:2.3.1.61] +synonym: "dihydrolipoyl transsuccinylase activity" EXACT [EC:2.3.1.61] +synonym: "enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "lipoate succinyltransferase (Escherichia coli) activity" EXACT [EC:2.3.1.61] +synonym: "lipoate succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "lipoic transsuccinylase activity" EXACT [EC:2.3.1.61] +synonym: "lipoyl transsuccinylase activity" EXACT [EC:2.3.1.61] +synonym: "succinyl-CoA:dihydrolipoamide S-succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "succinyl-CoA:dihydrolipoate S-succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity" EXACT [EC:2.3.1.61] +synonym: "succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity" EXACT [EC:2.3.1.61] +xref: EC:2.3.1.61 +is_a: GO:0016751 ! S-succinyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004150 +name: dihydroneopterin aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde." [EC:4.1.2.25] +synonym: "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming)" EXACT [EC:4.1.2.25] +synonym: "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity" EXACT [EC:4.1.2.25] +xref: EC:4.1.2.25 +xref: MetaCyc:H2NEOPTERINALDOL-RXN +xref: RHEA:10540 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0004151 +name: dihydroorotase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+)." [EC:3.5.2.3, RHEA:24296] +synonym: "(S)-dihydroorotate amidohydrolase activity" EXACT [EC:3.5.2.3] +synonym: "carbamoylaspartic dehydrase activity" EXACT [EC:3.5.2.3] +synonym: "DHOase activity" EXACT [EC:3.5.2.3] +synonym: "dihydroorotate hydrolase activity" EXACT [EC:3.5.2.3] +xref: EC:3.5.2.3 +xref: KEGG_REACTION:R01993 +xref: MetaCyc:DIHYDROOROT-RXN +xref: Reactome:R-HSA-73571 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O" +xref: RHEA:24296 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0004152 +name: dihydroorotate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate." [EC:1.3.5.2, RHEA:18073] +synonym: "(DHO) dehydrogenase activity" RELATED [EC:1.3.5.2] +synonym: "(S)-dihydroorotate:quinone oxidoreductase activity" EXACT systematic_synonym [EC:1.3.5.2] +synonym: "DHOdehase activity" EXACT [EC:1.3.5.2] +synonym: "dihydoorotic acid dehydrogenase activity" EXACT [EC:1.3.5.2] +synonym: "dihydroorotate:ubiquinone oxidoreductase activity" NARROW [EC:1.3.5.2] +xref: EC:1.3.5.2 +xref: KEGG_REACTION:R01868 +xref: MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-73569 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol" +xref: RHEA:18073 +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor + +[Term] +id: GO:0004153 +name: dihydropterin deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3." [DOI:10.1016/0020-1790(83)90018-5, FB:FBrf0039640, GOC:jl, ISSN:05829879] +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0004154 +name: dihydropterin oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide." [GOC:mah, PMID:1745247, PMID:6815189] +xref: EC:1.5.3 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0004155 +name: 6,7-dihydropteridine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine." [EC:1.5.1.34] +comment: Note that this function was formerly EC:1.6.99.7. +synonym: "5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.34] +synonym: "5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity" EXACT [EC:1.5.1.34] +synonym: "6,7-dihydropteridine:NAD(P)H oxidoreductase activity" EXACT [EC:1.5.1.34] +synonym: "DHPR activity" EXACT [EC:1.5.1.34] +synonym: "dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity" EXACT [EC:1.5.1.34] +synonym: "dihydropteridine reductase (NADH) activity" EXACT [EC:1.5.1.34] +synonym: "dihydropteridine reductase activity" EXACT [] +synonym: "dihydropteridine reduction" RELATED [] +synonym: "NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity" EXACT [EC:1.5.1.34] +synonym: "NAD(P)H2:6,7-dihydropteridine oxidoreductase activity" EXACT [EC:1.5.1.34] +synonym: "NADH-dihydropteridine reductase activity" EXACT [EC:1.5.1.34] +synonym: "NADPH-dihydropteridine reductase activity" EXACT [EC:1.5.1.34] +synonym: "NADPH-specific dihydropteridine reductase activity" EXACT [EC:1.5.1.34] +xref: EC:1.5.1.34 +xref: MetaCyc:1.5.1.34-RXN +xref: Reactome:R-HSA-71130 "q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+" +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004156 +name: dihydropteroate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate." [EC:2.5.1.15] +synonym: "(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity" EXACT [EC:2.5.1.15] +synonym: "2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity" EXACT [EC:2.5.1.15] +synonym: "7,8-dihydropteroate synthase activity" EXACT [EC:2.5.1.15] +synonym: "7,8-dihydropteroate synthetase activity" EXACT [EC:2.5.1.15] +synonym: "7,8-dihydropteroic acid synthetase activity" EXACT [EC:2.5.1.15] +synonym: "DHPS activity" EXACT [EC:2.5.1.15] +synonym: "dihydropteroate diphosphorylase activity" EXACT [EC:2.5.1.15] +synonym: "dihydropteroate pyrophosphorylase activity" EXACT [EC:2.5.1.15] +synonym: "dihydropteroate synthetase activity" EXACT [EC:2.5.1.15] +synonym: "dihydropteroic synthetase activity" EXACT [EC:2.5.1.15] +xref: EC:2.5.1.15 +xref: MetaCyc:H2PTEROATESYNTH-RXN +xref: RHEA:19949 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004157 +name: dihydropyrimidinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate." [EC:3.5.2.2] +synonym: "5,6-dihydropyrimidine amidohydrolase activity" EXACT [EC:3.5.2.2] +synonym: "D-hydantoinase activity" EXACT [EC:3.5.2.2] +synonym: "hydantoin peptidase activity" EXACT [EC:3.5.2.2] +synonym: "hydantoinase activity" EXACT [EC:3.5.2.2] +synonym: "hydropyrimidine hydrase activity" EXACT [EC:3.5.2.2] +synonym: "pyrimidine hydrase activity" EXACT [EC:3.5.2.2] +xref: EC:3.5.2.2 +xref: MetaCyc:DIHYDROPYRIMIDINASE-RXN +xref: Reactome:R-HSA-73589 "5,6-dihydrouracil + H2O => beta-ureidopropionate" +xref: Reactome:R-HSA-73618 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate" +xref: RHEA:16121 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0004158 +name: dihydroorotate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate." [EC:1.3.3.1, RHEA:15441] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "(S)-dihydroorotate:oxygen oxidoreductase activity" EXACT [EC:1.3.3.1] +synonym: "4,5-L-dihydroorotate:oxygen oxidoreductase activity" EXACT [EC:1.3.3.1] +xref: EC:1.3.3.1 +xref: RHEA:15441 +is_a: GO:0004152 ! dihydroorotate dehydrogenase activity +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0004159 +name: dihydrouracil dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+." [EC:1.3.1.1] +synonym: "5,6-dihydrouracil:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.1] +synonym: "dehydrogenase, dihydrouracil" EXACT [EC:1.3.1.1] +synonym: "pyrimidine reductase activity" EXACT [EC:1.3.1.1] +synonym: "thymine reductase activity" EXACT [EC:1.3.1.1] +synonym: "uracil reductase activity" EXACT [EC:1.3.1.1] +xref: EC:1.3.1.1 +xref: MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN +xref: RHEA:20189 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004160 +name: dihydroxy-acid dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O." [EC:4.2.1.9] +synonym: "2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)" EXACT [EC:4.2.1.9] +synonym: "2,3-dihydroxy-acid hydro-lyase activity" EXACT [EC:4.2.1.9] +synonym: "2,3-dihydroxyisovalerate dehydratase activity" EXACT [EC:4.2.1.9] +synonym: "acetohydroxyacid dehydratase activity" EXACT [EC:4.2.1.9] +synonym: "alpha,beta-dihydroxyacid dehydratase activity" EXACT [EC:4.2.1.9] +synonym: "alpha,beta-dihydroxyisovalerate dehydratase activity" EXACT [EC:4.2.1.9] +synonym: "DHAD" RELATED [EC:4.2.1.9] +synonym: "dihydroxy acid dehydrase activity" EXACT [EC:4.2.1.9] +xref: EC:4.2.1.9 +xref: MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN +xref: RHEA:20936 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004161 +name: dimethylallyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate." [EC:2.5.1.1] +comment: Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'. +synonym: "(2E,6E)-farnesyl diphosphate synthetase activity" EXACT [EC:2.5.1.1] +synonym: "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity" EXACT [EC:2.5.1.1] +synonym: "dimethylallyltransferase activity" EXACT [] +synonym: "diprenyltransferase activity" EXACT [EC:2.5.1.1] +synonym: "DMAPP:IPP-dimethylallyltransferase activity" EXACT [EC:2.5.1.1] +synonym: "geranyl diphosphate synthase" EXACT [] +synonym: "geranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.1] +synonym: "geranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.1] +synonym: "geranyl-diphosphate synthase activity" RELATED [EC:2.5.1.1] +synonym: "trans-farnesyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.1] +xref: EC:2.5.1.1 +xref: MetaCyc:GPPSYN-RXN +xref: Reactome:R-HSA-191322 "Addition of isopentenyl pyrophosphate to DMAPP" +xref: RHEA:22408 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0004162 +name: dimethylnitrosamine demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from N-nitrosodimethylamine." [GOC:mah] +synonym: "N-nitrosodimethylamine demethylase activity" EXACT [] +is_a: GO:0032451 ! demethylase activity + +[Term] +id: GO:0004163 +name: diphosphomevalonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate." [EC:4.1.1.33, RHEA:23732] +synonym: "5-pyrophosphomevalonate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)" EXACT [EC:4.1.1.33] +synonym: "ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)" EXACT [EC:4.1.1.33] +synonym: "mevalonate 5-diphosphate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "mevalonate diphosphate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "mevalonate pyrophosphate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "mevalonate-5-pyrophosphate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "pyrophosphomevalonate decarboxylase activity" EXACT [EC:4.1.1.33] +synonym: "pyrophosphomevalonic acid decarboxylase activity" EXACT [EC:4.1.1.33] +xref: EC:4.1.1.33 +xref: KEGG_REACTION:R01121 +xref: MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-191414 "MVD decarboxylates MVA5PP to IPPP" +xref: RHEA:23732 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004164 +name: diphthine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine." [EC:2.1.1.98] +synonym: "diphthine methyltransferase activity" EXACT [EC:2.1.1.98] +synonym: "S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity" EXACT [EC:2.1.1.98] +synonym: "S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity" EXACT [EC:2.1.1.98] +xref: EC:2.1.1.98 +xref: MetaCyc:RXN-11370 +xref: Reactome:R-HSA-5358484 "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2" +xref: RHEA:20145 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004165 +name: dodecenoyl-CoA delta-isomerase activity +namespace: molecular_function +alt_id: GO:0008461 +def: "Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA." [EC:5.3.3.8] +synonym: "3,2-trans-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] +synonym: "acetylene-allene isomerase activity" EXACT [EC:5.3.3.8] +synonym: "delta(3),Delta(2)-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] +synonym: "delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] +synonym: "delta3,Delta2-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] +synonym: "delta3-cis-delta2-trans-enoyl-CoA isomerase" BROAD [EC:5.3.3.8] +synonym: "dodecenoyl-CoA (3Z)-(2E)-isomerase activity" EXACT [EC:5.3.3.8] +synonym: "dodecenoyl-CoA D-isomerase activity" EXACT [] +synonym: "dodecenoyl-CoA Delta-isomerase activity" EXACT [EC:5.3.3.8] +synonym: "dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity" EXACT [EC:5.3.3.8] +synonym: "dodecenoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] +xref: EC:5.3.3.8 +xref: MetaCyc:ENOYL-COA-DELTA-ISOM-RXN +xref: Reactome:R-HSA-109338 "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA" +xref: Reactome:R-HSA-6809808 "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA" +xref: RHEA:23716 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0004166 +name: dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity +namespace: molecular_function +alt_id: GO:0004101 +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate." [EC:2.4.1.153] +synonym: "dolichyl phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "dolichyl phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "dolichyl-phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "dolichyl-phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +synonym: "uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] +xref: EC:2.4.1.153 +xref: MetaCyc:2.4.1.153-RXN +xref: RHEA:14693 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0004167 +name: dopachrome isomerase activity +namespace: molecular_function +alt_id: GO:0048059 +def: "Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate." [EC:5.3.3.12, RHEA:13041] +synonym: "DCF activity" EXACT [EC:5.3.3.12] +synonym: "DCT activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome conversion activity" BROAD [] +synonym: "dopachrome conversion factor activity" BROAD [EC:5.3.3.12] +synonym: "dopachrome Delta(7),Delta(2)-isomerase activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome delta-isomerase activity" EXACT [] +synonym: "dopachrome delta7,Delta2-isomerase activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome keto-enol isomerase activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome oxidoreductase activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome rearranging enzyme activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome tautomerase activity" EXACT [EC:5.3.3.12] +synonym: "dopachrome-rearranging enzyme" RELATED [EC:5.3.3.12] +synonym: "L-dopachrome isomerase activity" EXACT [EC:5.3.3.12] +synonym: "L-dopachrome keto-enol isomerase activity" EXACT [EC:5.3.3.12] +synonym: "L-dopachrome-methyl ester tautomerase activity" EXACT [EC:5.3.3.12] +synonym: "TRP activity" EXACT [EC:5.3.3.12] +synonym: "TRP-1" RELATED [EC:5.3.3.12] +synonym: "TRP-2" RELATED [EC:5.3.3.12] +synonym: "TRP2" RELATED [EC:5.3.3.12] +synonym: "tryosinase-related protein-2" RELATED [EC:5.3.3.12] +synonym: "tyrosinase-related protein 2 activity" EXACT [EC:5.3.3.12] +xref: EC:5.3.3.12 +xref: KEGG_REACTION:R03673 +xref: MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN +xref: RHEA:13041 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0004168 +name: dolichol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate." [EC:2.7.1.108] +synonym: "CTP:dolichol O-phosphotransferase activity" EXACT [EC:2.7.1.108] +synonym: "dolichol phosphokinase activity" EXACT [EC:2.7.1.108] +xref: EC:2.7.1.108 +xref: MetaCyc:DOLICHOL-KINASE-RXN +xref: Reactome:R-HSA-446195 "DOLK phosphorylates DCHOL to DOLP" +xref: Reactome:R-HSA-4755600 "Defective DOLK does not phosphorylate DCHOL" +xref: RHEA:13133 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004169 +name: dolichyl-phosphate-mannose-protein mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein." [EC:2.4.1.109, GOC:pr] +comment: Note that this activity has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543. +synonym: "dolichol phosphomannose-protein mannosyltransferase activity" EXACT [EC:2.4.1.109] +synonym: "dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity" EXACT [EC:2.4.1.109] +synonym: "dolichyl-phosphate-mannose-protein O-mannosyltransferase activity" EXACT [] +synonym: "O-glycoside mannosyltransferase" BROAD [] +synonym: "protein O-D-mannosyltransferase activity" EXACT [EC:2.4.1.109] +synonym: "protein O-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.109 +xref: MetaCyc:2.4.1.109-RXN +xref: Reactome:R-HSA-5615556 "Defective POMT2 does not transfer Man from Dol-P-Man to DAG1" +xref: Reactome:R-HSA-5615604 "Defective POMT1 does not transfer Man from Dol-P-Man to DAG1" +xref: Reactome:R-HSA-5615637 "POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653)" +is_a: GO:0000030 ! mannosyltransferase activity +relationship: part_of GO:0035269 ! protein O-linked mannosylation +property_value: RO:0002161 NCBITaxon:33090 + +[Term] +id: GO:0004170 +name: dUTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate." [RHEA:10248] +subset: goslim_chembl +synonym: "deoxyuridine-triphosphatase activity" EXACT [EC:3.6.1.23] +synonym: "desoxyuridine 5'-triphosphatase activity" EXACT [EC:3.6.1.23] +synonym: "desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.23] +synonym: "dUTP nucleotidohydrolase activity" EXACT [EC:3.6.1.23] +synonym: "dUTP pyrophosphatase activity" EXACT [] +synonym: "dUTPase activity" EXACT [EC:3.6.1.23] +xref: EC:3.6.1.23 +xref: KEGG_REACTION:R02100 +xref: MetaCyc:DUTP-PYROP-RXN +xref: Reactome:R-HSA-73666 "dUTP + H2O => dUMP + pyrophosphate" +xref: RHEA:10248 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity + +[Term] +id: GO:0004171 +name: obsolete deoxyhypusine synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine." [EC:2.5.1.46] +comment: This term was made obsolete because it represents a multistep reaction. +synonym: "[eIF-5A]-deoxyhypusine synthase" RELATED [] +synonym: "deoxyhypusine synthase activity" EXACT [] +is_obsolete: true +consider: GO:0008612 +consider: GO:0034038 + +[Term] +id: GO:0004172 +name: obsolete ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents two molecular functions. +synonym: "ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity" EXACT [] +is_obsolete: true +consider: GO:0050488 + +[Term] +id: GO:0004173 +name: ecdysone O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate." [EC:2.3.1.139, RHEA:15217] +synonym: "acyl-CoA:ecdysone acyltransferase activity" EXACT [EC:2.3.1.139] +synonym: "fatty acyl-CoA:ecdysone acyltransferase activity" EXACT [EC:2.3.1.139] +synonym: "palmitoyl-CoA:ecdysone palmitoyltransferase activity" EXACT [EC:2.3.1.139] +xref: EC:2.3.1.139 +xref: KEGG_REACTION:R02375 +xref: MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN +xref: RHEA:15217 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0004174 +name: electron-transferring-flavoprotein dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced ETF + ubiquinone = ETF + ubiquinol." [EC:1.5.5.1] +synonym: "electron transfer flavoprotein dehydrogenase activity" EXACT [EC:1.5.5.1] +synonym: "electron transfer flavoprotein Q oxidoreductase activity" EXACT [EC:1.5.5.1] +synonym: "electron transfer flavoprotein reductase activity" EXACT [EC:1.5.5.1] +synonym: "electron transfer flavoprotein-ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] +synonym: "electron-transferring-flavoprotein:ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] +synonym: "ETF dehydrogenase activity" EXACT [EC:1.5.5.1] +synonym: "ETF-QO activity" EXACT [EC:1.5.5.1] +synonym: "ETF-ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] +synonym: "ETF:ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] +xref: EC:1.5.5.1 +xref: MetaCyc:1.5.5.1-RXN +xref: Reactome:R-HSA-169270 "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2" +is_a: GO:0009055 ! electron transfer activity +is_a: GO:0016649 ! oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor +relationship: part_of GO:0022904 ! respiratory electron transport chain + +[Term] +id: GO:0004175 +name: endopeptidase activity +namespace: molecular_function +alt_id: GO:0016809 +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain." [http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] +synonym: "elastase activity" RELATED [GOC:krc] +synonym: "endoprotease activity" NARROW [] +synonym: "proteasome endopeptidase activity" NARROW [] +synonym: "proteinase" NARROW [] +xref: MetaCyc:RXN0-5195 +xref: Reactome:R-HSA-1168640 "Ubiquitinated IkB is degraded" +xref: Reactome:R-HSA-1234159 "Proteasome proteolyzes ub-HIF-alpha" +xref: Reactome:R-HSA-1236935 "Proteasomal cleavage of substrate" +xref: Reactome:R-HSA-1236970 "Proteasomal clevage of exogenous antigen" +xref: Reactome:R-HSA-1251997 "Cleavage of ERBB4m80 by gamma-scretase complex" +xref: Reactome:R-HSA-1433374 "Processing of SCF isoform 1" +xref: Reactome:R-HSA-1504193 "Ubiquitinated DVL is degraded by the proteasome" +xref: Reactome:R-HSA-174058 "Degradation of multiubiquitinated Cdh1" +xref: Reactome:R-HSA-174105 "Degradation of multiubiquitinated cell cycle proteins" +xref: Reactome:R-HSA-174202 "Degradation of multiubiquitinated Securin" +xref: Reactome:R-HSA-174203 "SCF-mediated degradation of Emi1" +xref: Reactome:R-HSA-174255 "Degradation multiubiquitinated Cyclin A" +xref: Reactome:R-HSA-180573 "Degradation of ubiquitinated CD4" +xref: Reactome:R-HSA-180603 "Proteosome-mediated degradation of APOBEC3G" +xref: Reactome:R-HSA-187574 "Degradation of ubiquitinated p27/p21 by the 26S proteasome" +xref: Reactome:R-HSA-188191 "APC/C:Cdh1-mediated degradation of Skp2" +xref: Reactome:R-HSA-193682 "gamma-secretase cleaves the p75NTR transmembrane domain" +xref: Reactome:R-HSA-209061 "Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex" +xref: Reactome:R-HSA-211715 "Proteasome mediated degradation of PAK-2p34" +xref: Reactome:R-HSA-2130282 "Degradation of ubiquitinated beta catenin by the proteasome" +xref: Reactome:R-HSA-2213200 "Release of endostatin-like peptides" +xref: Reactome:R-HSA-264458 "Proteasome mediated degradation of COP1" +xref: Reactome:R-HSA-353125 "26S proteosome degrades ODC holoenzyme complex" +xref: Reactome:R-HSA-3640874 "Ub-RibC-AXIN is degraded by the proteasome" +xref: Reactome:R-HSA-3928656 "gamma-secretase cleaves EPHB2" +xref: Reactome:R-HSA-450466 "AUF1:mRNA complex is destroyed" +xref: Reactome:R-HSA-4608855 "PRICKLE1 is degraded by the proteasome" +xref: Reactome:R-HSA-4641256 "Ubiquitinated AXIN is degraded by the proteasome" +xref: Reactome:R-HSA-4641260 "Ubiquitinated DVL1 is degraded by the proteasome" +xref: Reactome:R-HSA-5358340 "Autoproteolytic cleavage of Hh precursors" +xref: Reactome:R-HSA-5358460 "HPE SHH variants don't undergo autoproteolytic cleavage" +xref: Reactome:R-HSA-5362448 "Hh C-terminal fragments are degraded by the proteasome" +xref: Reactome:R-HSA-5387392 "processing defective Hh variants are degraded by the proteasome" +xref: Reactome:R-HSA-5607724 "26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex" +xref: Reactome:R-HSA-5607731 "26S proteasome processes p-7S-p100:RELB to form p52:RELB" +xref: Reactome:R-HSA-5610754 "GLI3 is partially degraded by the proteasome to yield the GLI3 repressor" +xref: Reactome:R-HSA-5610757 "GLI2 is degraded by the proteasome" +xref: Reactome:R-HSA-5610758 "GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP" +xref: Reactome:R-HSA-5610760 "GLI1 is degraded by the proteasome after ubiquitination by ITCH" +xref: Reactome:R-HSA-5635854 "GLI2,3 are degraded by the proteasome" +xref: Reactome:R-HSA-5635868 "ub-GLI is degraded by the proteasome" +xref: Reactome:R-HSA-5658430 "NF1 is degraded by the proteasome" +xref: Reactome:R-HSA-5668481 "Protesomal degradation of K48polyUb-TRAF3" +xref: Reactome:R-HSA-5668520 "26Sproteasome degrades K48polyUb-NIK" +xref: Reactome:R-HSA-5687112 "MAPK6 is degraded by the 26S proteasome" +xref: Reactome:R-HSA-5693081 "FURIN cleaves 7K-BACE1 to 7K-BACE1(46-501)" +xref: Reactome:R-HSA-6784628 "PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer" +xref: Reactome:R-HSA-6784676 "PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer" +xref: Reactome:R-HSA-68825 "Ubiquitinated geminin is degraded by the proteasome" +xref: Reactome:R-HSA-68948 "Ubiquitinated Orc1 is degraded by the proteasome" +xref: Reactome:R-HSA-69016 "Ubiquitinated Cdc6 is degraded by the proteasome" +xref: Reactome:R-HSA-69600 "Proteolytic degradation of ubiquitinated-Cdc25A" +xref: Reactome:R-HSA-74730 "Insulin degradation" +xref: Reactome:R-HSA-75825 "Proteasome mediated degradation of Cyclin D1" +xref: Reactome:R-HSA-8849797 "Membrane proteases cleave Profilaggrin producing Filaggrin" +xref: Reactome:R-HSA-8850992 "Proteasome degrades polyubiquitinated PTEN" +xref: Reactome:R-HSA-8852354 "GTSE1 facilitates proteasome-mediated degradation of TP53" +xref: Reactome:R-HSA-8854044 "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7" +xref: Reactome:R-HSA-8854071 "Proteasome-mediated degradation of PolyUb-FBXL7" +xref: Reactome:R-HSA-8866553 "misfolded CFTR is degraded by the 26S proteasome" +xref: Reactome:R-HSA-8866858 "CFTR F508del is degraded by the 26S proteasome" +xref: Reactome:R-HSA-8934819 "Cytoplasmic proteases cleave Profilaggrin producing Filaggrin" +xref: Reactome:R-HSA-8939801 "26S proteasome degrades PolyUb-RUNX2" +xref: Reactome:R-HSA-8952408 "Polyubiquitinated RUNX3 is degraded by the proteasome" +xref: Reactome:R-HSA-8957265 "26S proteasome degrades TP73 polyubiquitinated by ITCH" +xref: Reactome:R-HSA-9008110 "Proteasome degrades polyubiquitinated RUNX2" +xref: Reactome:R-HSA-9008475 "Proteasome degrades polyubiquitinated RUNX2" +xref: Reactome:R-HSA-9009362 "Proteasome degrades PolyUb-RUNX2" +xref: Reactome:R-HSA-9010096 "Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713)" +xref: Reactome:R-HSA-9011313 "Proteasome degrades ubiquitinated ROBO3.1" +xref: Reactome:R-HSA-9604642 "Proteasome degrades ubiquitinated NICD4" +xref: Reactome:R-HSA-983150 "Proteasomal cleavage of substrate" +xref: Reactome:R-HSA-983158 "Trimming of peptides in ER" +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0004176 +name: ATP-dependent peptidase activity +namespace: molecular_function +alt_id: GO:0004280 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds." [GOC:mah] +synonym: "ATP-dependent proteolysis" RELATED [GOC:mah] +is_a: GO:0016887 ! ATPase activity +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0004177 +name: aminopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain." [GOC:jl, ISBN:0198506732] +xref: EC:3.4.11 +xref: MetaCyc:RXN0-5052 +xref: Reactome:R-HSA-1236954 "Trimming of peptides by IRAP in endocytic vesicles" +xref: Reactome:R-HSA-2534096 "METAP1/2 demethylates GNAT1" +xref: Reactome:R-HSA-8851929 "AOPEP:Zn2+ hydrolyses AGT(35-41) to AGT(36-41)" +xref: Reactome:R-HSA-983162 "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases" +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0004178 +name: obsolete leucyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro." [EC:3.4.11.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminopeptidase II" RELATED [EC:3.4.11.1] +synonym: "cathepsin III" RELATED [EC:3.4.11.1] +synonym: "cytosol aminopeptidase activity" NARROW [EC:3.4.11.1] +synonym: "FTBL proteins" RELATED [EC:3.4.11.1] +synonym: "L-leucine aminopeptidase activity" EXACT [EC:3.4.11.1] +synonym: "leucinamide aminopeptidase activity" EXACT [EC:3.4.11.1] +synonym: "leucinaminopeptidase activity" EXACT [EC:3.4.11.1] +synonym: "leucine aminopeptidase activity" EXACT [EC:3.4.11.1] +synonym: "leucyl aminopeptidase activity" EXACT [] +synonym: "leucyl peptidase activity" EXACT [EC:3.4.11.1] +synonym: "peptidase S activity" NARROW [EC:3.4.11.1] +synonym: "proteinates FTBL" RELATED [EC:3.4.11.1] +xref: EC:3.4.11.1 +xref: MetaCyc:3.4.11.1-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0004179 +name: obsolete membrane alanyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide." [EC:3.4.11.2] +comment: This term was made obsolete because it represents a gene product. +synonym: "alanine-specific aminopeptidase activity" EXACT [EC:3.4.11.2] +synonym: "alanyl aminopeptidase activity" EXACT [EC:3.4.11.2] +synonym: "amino-oligopeptidase activity" EXACT [EC:3.4.11.2] +synonym: "aminopeptidase M activity" NARROW [EC:3.4.11.2] +synonym: "aminopeptidase N activity" NARROW [EC:3.4.11.2] +synonym: "CD13" RELATED [EC:3.4.11.2] +synonym: "cysteinylglycinase activity" EXACT [EC:3.4.11.2] +synonym: "cysteinylglycine dipeptidase activity" EXACT [EC:3.4.11.2] +synonym: "L-alanine aminopeptidase activity" EXACT [EC:3.4.11.2] +synonym: "membrane alanine aminopeptidase activity" NARROW [EC:3.4.11.2] +synonym: "membrane alanyl aminopeptidase activity" EXACT [] +synonym: "membrane aminopeptidase I activity" NARROW [EC:3.4.11.2] +synonym: "microsomal aminopeptidase activity" NARROW [EC:3.4.11.2] +synonym: "particle-bound aminopeptidase activity" NARROW [EC:3.4.11.2] +synonym: "peptidase E activity" BROAD [EC:3.4.11.2] +synonym: "pseudo leucine aminopeptidase activity" EXACT [EC:3.4.11.2] +xref: EC:3.4.11.2 +xref: MetaCyc:3.4.11.2-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0004180 +name: carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide." [ISBN:0198506732] +xref: Reactome:R-HSA-1247910 "CNDP2:2Mn2+ dimer hydrolyses CysGly" +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0004181 +name: metallocarboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0198506732] +xref: EC:3.4.17 +xref: Reactome:R-HSA-2022378 "ACE2 hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9)" +xref: Reactome:R-HSA-2022379 "ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7)" +xref: Reactome:R-HSA-2028294 "Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9)" +xref: Reactome:R-HSA-8852809 "CPN, CPB2 cleave C3a, C5a" +xref: Reactome:R-HSA-8866105 "CCPs deglutamylate tubulin" +xref: Reactome:R-HSA-8955712 "TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin" +xref: Reactome:R-HSA-9023159 "Carboxypeptidase E cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87))" +xref: Reactome:R-HSA-9023163 "Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54)" +is_a: GO:0004180 ! carboxypeptidase activity +is_a: GO:0008235 ! metalloexopeptidase activity + +[Term] +id: GO:0004182 +name: obsolete carboxypeptidase A activity +namespace: molecular_function +alt_id: GO:0008731 +def: "OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro." [EC:3.4.17.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase A activity" EXACT [] +synonym: "carboxypolypeptidase activity" EXACT [EC:3.4.17.1] +synonym: "pancreatic carboxypeptidase A" RELATED [EC:3.4.17.1] +synonym: "tissue carboxypeptidase A" RELATED [EC:3.4.17.1] +xref: EC:3.4.17.1 +xref: MetaCyc:CARBOXYPEPTIDASE-A-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0004183 +name: obsolete carboxypeptidase E activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents." [EC:3.4.17.10] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase E activity" EXACT [] +synonym: "carboxypeptidase H activity" EXACT [] +synonym: "cobalt-stimulated chromaffin granule carboxypeptidase activity" EXACT [EC:3.4.17.10] +synonym: "enkephalin convertase activity" NARROW [EC:3.4.17.10] +synonym: "enkephalin precursor carboxypeptidase activity" EXACT [EC:3.4.17.10] +synonym: "enkephalin-precursor endopeptidase activity" EXACT [EC:3.4.17.10] +synonym: "insulin granule-associated carboxypeptidase activity" EXACT [EC:3.4.17.10] +synonym: "membrane-bound carboxypeptidase activity" EXACT [EC:3.4.17.10] +synonym: "peptidyl-L-lysine(-L-arginine) hydrolase" BROAD [EC:3.4.17.10] +xref: EC:3.4.17.10 +xref: MetaCyc:CARBOXYPEPTIDASE-H-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0004184 +name: obsolete lysine carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma." [EC:3.4.17.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "anaphylatoxin inactivator activity" NARROW [EC:3.4.17.3] +synonym: "arginine carboxypeptidase activity" EXACT [EC:3.4.17.3] +synonym: "bradykinase activity" EXACT [EC:3.4.17.3] +synonym: "bradykinin-decomposing enzyme" RELATED [EC:3.4.17.3] +synonym: "carboxypeptidase N activity" EXACT [] +synonym: "CPase N" RELATED [EC:3.4.17.3] +synonym: "creatine kinase conversion factor" RELATED [EC:3.4.17.3] +synonym: "creatinine kinase convertase activity" EXACT [EC:3.4.17.3] +synonym: "hippuryllysine hydrolase activity" EXACT [EC:3.4.17.3] +synonym: "kininase I activity" EXACT [EC:3.4.17.3] +synonym: "kininase Ia" RELATED [EC:3.4.17.3] +synonym: "lysine (arginine) carboxypeptidase activity" EXACT [] +synonym: "lysine carboxypeptidase activity" EXACT [] +synonym: "lysine(arginine) carboxypeptidase activity" EXACT [EC:3.4.17.3] +synonym: "peptidyl-L-lysine(-L-arginine) hydrolase" BROAD [EC:3.4.17.3] +synonym: "plasma carboxypeptidase B" RELATED [EC:3.4.17.3] +xref: EC:3.4.17.3 +xref: MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0004185 +name: serine-type carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094] +synonym: "serine carboxypeptidase activity" EXACT [] +xref: EC:3.4.16 +xref: Reactome:R-HSA-158251 "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer" +is_a: GO:0004180 ! carboxypeptidase activity +is_a: GO:0070008 ! serine-type exopeptidase activity + +[Term] +id: GO:0004186 +name: obsolete carboxypeptidase C activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity." [EC:3.4.16.5] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase C activity" EXACT [] +synonym: "carboxypeptidase Y activity" EXACT [EC:3.4.16.5] +synonym: "cathepsin A activity" NARROW [EC:3.4.16.5] +synonym: "deamidase" RELATED [EC:3.4.16.5] +synonym: "lysosomal carboxypeptidase A" NARROW [EC:3.4.16.5] +synonym: "lysosomal protective protein activity" NARROW [EC:3.4.16.5] +synonym: "serine carboxypeptidase I activity" EXACT [EC:3.4.16.5] +synonym: "serine-type carboxypeptidase I activity" EXACT [EC:3.4.16.5] +synonym: "vacuolar carboxypeptidase Y" NARROW [] +xref: EC:3.4.16.5 +xref: MetaCyc:3.4.16.5-RXN +is_obsolete: true +replaced_by: GO:0004185 + +[Term] +id: GO:0004187 +name: obsolete carboxypeptidase D activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents." [EC:3.4.16.6] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase D activity" EXACT [] +synonym: "carboxypeptidase Kex1" RELATED [EC:3.4.16.6] +synonym: "carboxypeptidase KEX1 activity" NARROW [EC:3.4.16.6] +synonym: "carboxypeptidase S1 activity" EXACT [EC:3.4.16.6] +synonym: "cereal serine carboxypeptidase II" RELATED [EC:3.4.16.6] +synonym: "CPDW-II" RELATED [EC:3.4.16.6] +synonym: "gene KEX1 serine carboxypeptidase" NARROW [EC:3.4.16.6] +synonym: "KEX1 carboxypeptidase activity" EXACT [EC:3.4.16.6] +synonym: "KEX1 proteinase activity" EXACT [EC:3.4.16.6] +synonym: "KEX1DELTAp" RELATED [EC:3.4.16.6] +synonym: "saccharomyces cerevisiae KEX1 gene product" RELATED [EC:3.4.16.6] +xref: EC:3.4.16.6 +xref: MetaCyc:3.4.16.6-RXN +is_obsolete: true +replaced_by: GO:0004185 + +[Term] +id: GO:0004188 +name: obsolete serine-type Pro-X carboxypeptidase activity +namespace: molecular_function +alt_id: GO:0008323 +def: "OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid." [EC:3.4.16.2] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminoacylproline carboxypeptidase activity" EXACT [EC:3.4.16.2] +synonym: "angiotensinase C activity" NARROW [EC:3.4.16.2] +synonym: "lysosomal carboxypeptidase C activity" NARROW [EC:3.4.16.2] +synonym: "lysosomal Pro-X carboxypeptidase activity" NARROW [] +synonym: "lysosomal Pro-Xaa carboxypeptidase activity" EXACT [EC:3.4.16.2] +synonym: "PCP" RELATED [EC:3.4.16.2] +synonym: "peptidylprolylamino acid carboxypeptidase activity" EXACT [EC:3.4.16.2] +synonym: "proline carboxypeptidase activity" EXACT [EC:3.4.16.2] +synonym: "proline-specific carboxypeptidase P" RELATED [EC:3.4.16.2] +synonym: "prolyl carboxypeptidase activity" EXACT [EC:3.4.16.2] +synonym: "serine-type Pro-X carboxypeptidase activity" EXACT [] +xref: EC:3.4.16.2 +xref: MetaCyc:3.4.16.2-RXN +is_obsolete: true +replaced_by: GO:0004185 + +[Term] +id: GO:0004189 +name: obsolete tubulinyl-Tyr carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr." [EC:3.4.17.17] +comment: This term was made obsolete because it represents a gene product. +synonym: "brain I carboxypeptidase activity" EXACT [EC:3.4.17.17] +synonym: "carboxypeptidase-tubulin activity" EXACT [EC:3.4.17.17] +synonym: "soluble carboxypeptidase activity" RELATED [EC:3.4.17.17] +synonym: "TTCPase activity" EXACT [EC:3.4.17.17] +synonym: "tubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] +synonym: "tubulin-tyrosine carboxypeptidase activity" EXACT [EC:3.4.17.17] +synonym: "tubulinyl-Tyr carboxypeptidase activity" EXACT [] +synonym: "tubulinyl-tyrosine carboxypeptidase activity" EXACT [] +synonym: "tubulinyltyrosine carboxypeptidase activity" EXACT [EC:3.4.17.17] +synonym: "tyrosinotubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] +synonym: "tyrosyltubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] +xref: EC:3.4.17.17 +xref: MetaCyc:3.4.17.17-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0004190 +name: aspartic-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [ISBN:0198506732] +synonym: "aspartate protease activity" NARROW [GOC:mah, GOC:vw] +synonym: "aspartic endopeptidase activity" EXACT [] +synonym: "aspartic protease activity" NARROW [] +synonym: "aspartyl protease activity" NARROW [] +synonym: "carboxyl protease activity" NARROW [] +xref: EC:3.4.23 +xref: Reactome:R-HSA-157353 "NEXT1 is cleaved to produce NICD1" +xref: Reactome:R-HSA-157640 "NEXT2 is cleaved to produce NICD2" +xref: Reactome:R-HSA-2022403 "Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)" +xref: Reactome:R-HSA-2022412 "Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10)" +xref: Reactome:R-HSA-2065357 "Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)" +xref: Reactome:R-HSA-2220988 "NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants" +xref: Reactome:R-HSA-373705 "Caspase cleavage of DCC" +xref: Reactome:R-HSA-9013361 "NEXT3 is cleaved to produce NICD3" +xref: Reactome:R-HSA-9017817 "Gamma-secretase cleaves YBX1:NOTCH3" +xref: Reactome:R-HSA-9604294 "Gamma-secretase cleaves NOTCH4" +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0070001 ! aspartic-type peptidase activity + +[Term] +id: GO:0004191 +name: obsolete barrierpepsin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor." [EC:3.4.23.35] +comment: This term was made obsolete because it represents a gene product. +synonym: "Bar proteinase activity" NARROW [EC:3.4.23.35] +synonym: "barrier proteinase activity" EXACT [EC:3.4.23.35] +synonym: "barrierpepsin activity" EXACT [] +synonym: "extracellular 'barrier' protein activity" RELATED [EC:3.4.23.35] +xref: EC:3.4.23.35 +xref: MetaCyc:3.4.23.35-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004192 +name: obsolete cathepsin D activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin." [EC:3.4.23.5] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin D activity" EXACT [] +xref: EC:3.4.23.5 +xref: MetaCyc:3.4.23.5-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004193 +name: obsolete cathepsin E activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity." [EC:3.4.23.34] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin D-like acid proteinase activity" EXACT [EC:3.4.23.34] +synonym: "cathepsin D-type proteinase activity" EXACT [EC:3.4.23.34] +synonym: "cathepsin E activity" EXACT [] +synonym: "cathepsin E-like acid proteinase activity" EXACT [EC:3.4.23.34] +synonym: "EMAP" RELATED [EC:3.4.23.34] +synonym: "erythrocyte membrane aspartic proteinase activity" NARROW [EC:3.4.23.34] +synonym: "non-pepsin proteinase activity" EXACT [EC:3.4.23.34] +synonym: "slow-moving proteinase activity" RELATED [EC:3.4.23.34] +synonym: "SMP" RELATED [EC:3.4.23.34] +xref: EC:3.4.23.34 +xref: MetaCyc:3.4.23.34-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004194 +name: obsolete pepsin A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin." [EC:3.4.23.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "elixir lactate of pepsin" RELATED [EC:3.4.23.1] +synonym: "fundus-pepsin" RELATED [EC:3.4.23.1] +synonym: "lactated pepsin" RELATED [EC:3.4.23.1] +synonym: "lactated pepsin elixir" RELATED [EC:3.4.23.1] +synonym: "P I" RELATED [EC:3.4.23.1] +synonym: "P II" RELATED [EC:3.4.23.1] +synonym: "pepsin A activity" EXACT [] +synonym: "pepsin activity" BROAD [EC:3.4.23.1] +synonym: "pepsin D" RELATED [EC:3.4.23.1] +synonym: "pepsin fortior" RELATED [EC:3.4.23.1] +synonym: "pepsin R" RELATED [EC:3.4.23.1] +xref: EC:3.4.23.1 +xref: MetaCyc:3.4.23.1-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004195 +name: obsolete renin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I." [EC:3.4.23.15] +comment: This term was made obsolete because it represents a gene product. +synonym: "angiotensin-forming enzyme activity" EXACT [EC:3.4.23.15] +synonym: "angiotensinogenase activity" EXACT [EC:3.4.23.15] +synonym: "renin activity" EXACT [] +xref: EC:3.4.23.15 +xref: MetaCyc:3.4.23.15-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004196 +name: obsolete saccharopepsin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24." [EC:3.4.23.25] +comment: This term was made obsolete because it represents a gene product. +synonym: "aspartic proteinase yscA" RELATED [EC:3.4.23.25] +synonym: "PRA" RELATED [EC:3.4.23.25] +synonym: "proteinase A" RELATED [EC:3.4.23.25] +synonym: "proteinase yscA" RELATED [EC:3.4.23.25] +synonym: "Saccharomyces aspartic proteinase activity" NARROW [EC:3.4.23.25] +synonym: "saccharomyces aspartic proteinase activity" EXACT [EC:3.4.23.25] +synonym: "saccharomyces cerevisiae aspartic proteinase A" RELATED [EC:3.4.23.25] +synonym: "saccharopepsin activity" EXACT [] +synonym: "yeast endopeptidase A activity" NARROW [EC:3.4.23.25] +synonym: "yeast proteinase A" RELATED [EC:3.4.23.25] +xref: EC:3.4.23.25 +xref: MetaCyc:3.4.23.25-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0004197 +name: cysteine-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] +synonym: "caspase activity" NARROW [GOC:mtg_apoptosis] +synonym: "lysosomal cysteine-type endopeptidase" NARROW [] +synonym: "metacaspase activity" NARROW [GOC:mtg_apoptosis] +synonym: "thiol endopeptidase activity" EXACT [] +xref: EC:3.4.22 +xref: Reactome:R-HSA-114252 "Cleavage of Procaspase-3 by the apoptosome" +xref: Reactome:R-HSA-114259 "Cleavage of Procaspase9 to caspase9" +xref: Reactome:R-HSA-114261 "Cleavage of Procaspase-7 by the apoptosome" +xref: Reactome:R-HSA-1236948 "Antigen processing by cathepsin S in endosoytic vesicle" +xref: Reactome:R-HSA-139898 "Caspase-8 activates BID by cleavage" +xref: Reactome:R-HSA-139952 "Caspase-8 processing in the DISC" +xref: Reactome:R-HSA-1678920 "TLR processing at low pH" +xref: Reactome:R-HSA-1678981 "TLR9 processing at neutral pH" +xref: Reactome:R-HSA-201595 "Caspase-mediated cleavage of plakophilin-1" +xref: Reactome:R-HSA-201603 "Caspase-mediated cleavage of PKC theta" +xref: Reactome:R-HSA-201608 "Caspase-mediated cleavage of alpha adducin" +xref: Reactome:R-HSA-201611 "Caspase-mediated cleavage of Rock-1" +xref: Reactome:R-HSA-201622 "Caspase-mediated cleavage of gelsolin" +xref: Reactome:R-HSA-201628 "Caspase-mediated cleavage of vimentin at DSVD (85)" +xref: Reactome:R-HSA-201629 "Caspase-mediated cleavage of Tau" +xref: Reactome:R-HSA-201630 "Caspase-mediated cleavage of Acinus" +xref: Reactome:R-HSA-201631 "Caspase-mediated cleavage of Desmoglein 3" +xref: Reactome:R-HSA-201634 "Caspase-mediated cleavage of FADK 1" +xref: Reactome:R-HSA-201636 "Caspase-mediated cleavage of Desmoplakin" +xref: Reactome:R-HSA-201637 "Caspase-mediated cleavage of plectin-1" +xref: Reactome:R-HSA-201639 "Caspase-mediated cleavage of GAS2" +xref: Reactome:R-HSA-201640 "Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha" +xref: Reactome:R-HSA-2028692 "Cleavage of p-STK4 (p-MST1) by caspase 3" +xref: Reactome:R-HSA-2028697 "Cleavage of p-STK3 (p-MST2) by caspase 3" +xref: Reactome:R-HSA-202917 "Caspase-mediated cleavage of Desmoglein 1" +xref: Reactome:R-HSA-202939 "Caspase-mediated cleavage of E-Cadherin" +xref: Reactome:R-HSA-202947 "Caspase mediated cleavage of APC" +xref: Reactome:R-HSA-202960 "Caspase mediated cleavage of C-IAP1" +xref: Reactome:R-HSA-202966 "Caspase mediated cleavage of HIP-55" +xref: Reactome:R-HSA-202967 "Caspase mediated cleavage of alpha-II-Fodrin" +xref: Reactome:R-HSA-202969 "Caspase mediated cleavage of beta-catenin" +xref: Reactome:R-HSA-211186 "Cleavage of DFF45 (224) by caspase-3" +xref: Reactome:R-HSA-211190 "Caspase 3-mediated cleavage of DFF45 (117)" +xref: Reactome:R-HSA-211651 "Cleavage of PAK-2 at 212" +xref: Reactome:R-HSA-212552 "Caspase 3-mediated cleavage of PKC delta" +xref: Reactome:R-HSA-2130336 "Initial proteolyis of Ii by aspartic proteases to lip22" +xref: Reactome:R-HSA-2130349 "Generation of CLIP from lip10" +xref: Reactome:R-HSA-2130504 "Cleavage of lip22 to lip10" +xref: Reactome:R-HSA-2130706 "MHC class II antigen processing" +xref: Reactome:R-HSA-2562564 "Caspase-8 processing within TLR4 complex" +xref: Reactome:R-HSA-264865 "Caspase-mediated cleavage of Lamin A" +xref: Reactome:R-HSA-264871 "Caspase-mediated cleavage of Lamin B1" +xref: Reactome:R-HSA-3465448 "Caspase-8 and FLIP(L) processing at DISC" +xref: Reactome:R-HSA-350158 "LGMN degrades GC" +xref: Reactome:R-HSA-350318 "Caspase-mediated cleavage of vimentin at TNLD (429)" +xref: Reactome:R-HSA-350319 "Caspase mediated cleavage of vimentin at IDVD (259)" +xref: Reactome:R-HSA-350651 "Caspase-mediated cleavage of MASK" +xref: Reactome:R-HSA-351849 "Caspase-mediated cleavage of Etk" +xref: Reactome:R-HSA-351871 "Caspase-mediated cleavage of Z0-2" +xref: Reactome:R-HSA-351876 "Caspase-mediated cleavage of occludin" +xref: Reactome:R-HSA-351877 "Caspase-mediated cleavage of Desmoglein 2" +xref: Reactome:R-HSA-351894 "Caspase mediated cleavage of BAP31" +xref: Reactome:R-HSA-351901 "Caspase-mediated cleavage of MST3" +xref: Reactome:R-HSA-351913 "Caspase-mediated cleavage of TJP1" +xref: Reactome:R-HSA-351936 "Caspase-mediated cleavage of claspin" +xref: Reactome:R-HSA-352268 "Cleavage of Satb1" +xref: Reactome:R-HSA-418845 "Activation of caspase-3" +xref: Reactome:R-HSA-418846 "Caspase cleavage of UNC5A" +xref: Reactome:R-HSA-418852 "Caspase cleavage of UNC5B" +xref: Reactome:R-HSA-448703 "Interleukin-1 family precursors are cleaved by caspase-1" +xref: Reactome:R-HSA-5357828 "RIP1 is cleaved by CASP8" +xref: Reactome:R-HSA-5634228 "TRAF1 is cleaved by caspases" +xref: Reactome:R-HSA-5660663 "Caspase-8 cleaves IL1B precursor" +xref: Reactome:R-HSA-5681987 "LC3 is cleaved by ATG4" +xref: Reactome:R-HSA-5682377 "LC3 de-lipidation by ATG4" +xref: Reactome:R-HSA-6814387 "CASP14 cleaves filaggrin" +xref: Reactome:R-HSA-9012556 "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37" +xref: Reactome:R-HSA-9013895 "Caspase-8 processing within TLR3 complex" +xref: Reactome:R-HSA-933532 "Processing of caspases" +xref: Reactome:R-HSA-9603534 "Unknown caspase cleaves NTRK3" +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0008234 ! cysteine-type peptidase activity + +[Term] +id: GO:0004198 +name: calcium-dependent cysteine-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium." [GOC:mah] +synonym: "calpain activity" NARROW [] +xref: Reactome:R-HSA-8848658 "CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins" +xref: Reactome:R-HSA-8863012 "Calpain cleaves p35 to p25" +is_a: GO:0004197 ! cysteine-type endopeptidase activity + +[Term] +id: GO:0004200 +name: obsolete signaling (initiator) caspase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it includes biological process information. +synonym: "signaling (initiator) caspase activity" EXACT [] +synonym: "signalling (initiator) caspase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 +consider: GO:0006915 + +[Term] +id: GO:0004201 +name: obsolete caspase-1 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec." [EC:3.4.22.36] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-1 activity" EXACT [] +synonym: "ICE" BROAD [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004202 +name: obsolete caspase-2 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-2 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004203 +name: obsolete caspase-4 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-4 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004204 +name: obsolete caspase-5 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-5 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004205 +name: obsolete caspase-8 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-8 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004206 +name: obsolete caspase-10 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-10 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004207 +name: obsolete effector caspase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it includes biological process information. +synonym: "effector caspase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 +consider: GO:0006915 + +[Term] +id: GO:0004208 +name: obsolete caspase-3 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis." [ISBN:0120793709] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-3 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004209 +name: obsolete caspase-6 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-6 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004210 +name: obsolete caspase-7 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-7 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004211 +name: obsolete caspase-9 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase-9 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004212 +name: obsolete lysosomal cysteine-type endopeptidase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "lysosomal cysteine-type endopeptidase" EXACT [] +is_obsolete: true +consider: GO:0004197 +consider: GO:0005764 + +[Term] +id: GO:0004213 +name: obsolete cathepsin B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides." [EC:3.4.22.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin B activity" EXACT [] +synonym: "cathepsin B1 activity" EXACT [EC:3.4.22.1] +synonym: "cathepsin II" RELATED [EC:3.4.22.1] +xref: EC:3.4.22.1 +xref: MetaCyc:3.4.22.1-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004214 +name: obsolete dipeptidyl-peptidase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro." [EC:3.4.14.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin C activity" EXACT [EC:3.4.14.1] +synonym: "cathepsin J activity" EXACT [EC:3.4.14.1] +synonym: "DAP I" RELATED [EC:3.4.14.1] +synonym: "dipeptide arylamidase I" RELATED [EC:3.4.14.1] +synonym: "dipeptidyl aminopeptidase I activity" EXACT [EC:3.4.14.1] +synonym: "dipeptidyl transferase activity" EXACT [EC:3.4.14.1] +synonym: "dipeptidyl-peptidase I activity" EXACT [] +xref: EC:3.4.14.1 +xref: MetaCyc:3.4.14.1-RXN +is_obsolete: true +consider: GO:0008234 +consider: GO:0008239 + +[Term] +id: GO:0004215 +name: obsolete cathepsin H activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase." [EC:3.4.22.16] +comment: This term was made obsolete because it represents a gene product. +synonym: "aleurain activity" EXACT [EC:3.4.22.16] +synonym: "benzoylarginine-naphthylamide (BANA) hydrolase activity" EXACT [EC:3.4.22.16] +synonym: "cathepsin B3 activity" EXACT [EC:3.4.22.16] +synonym: "cathepsin Ba" RELATED [EC:3.4.22.16] +synonym: "cathepsin BA activity" EXACT [EC:3.4.22.16] +synonym: "cathepsin H activity" EXACT [] +synonym: "N-benzoylarginine-beta-naphthylamide hydrolase activity" EXACT [EC:3.4.22.16] +xref: EC:3.4.22.16 +xref: MetaCyc:3.4.22.16-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004216 +name: obsolete cathepsin K activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg." [EC:3.4.22.38] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin K activity" EXACT [] +synonym: "cathepsin O activity" EXACT [EC:3.4.22.38] +synonym: "cathepsin O2 activity" EXACT [EC:3.4.22.38] +synonym: "cathepsin X activity" EXACT [EC:3.4.22.38] +xref: EC:3.4.22.38 +xref: MetaCyc:3.4.22.38-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004217 +name: obsolete cathepsin L activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity." [EC:3.4.22.15] +comment: This term was made obsolete because it represents a gene product. +synonym: "Aldrichina grahami cysteine proteinase" NARROW [EC:3.4.22.15] +synonym: "cathepsin L activity" EXACT [] +xref: EC:3.4.22.15 +xref: MetaCyc:3.4.22.15-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004218 +name: obsolete cathepsin S activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds." [EC:3.4.22.27] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin S activity" EXACT [] +xref: EC:3.4.22.27 +xref: MetaCyc:3.4.22.27-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0004219 +name: obsolete pyroglutamyl-peptidase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide." [EC:3.4.19.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "5-oxoprolyl-peptidase activity" EXACT [EC:3.4.19.3] +synonym: "L-pyroglutamyl peptide hydrolase activity" EXACT [EC:3.4.19.3] +synonym: "L-pyrrolidonecarboxylate peptidase activity" EXACT [EC:3.4.19.3] +synonym: "PYRase activity" EXACT [EC:3.4.19.3] +synonym: "pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyroglutamidase activity" EXACT [EC:3.4.19.3] +synonym: "pyroglutamyl aminopeptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyroglutamyl-peptidase I activity" EXACT [] +synonym: "pyrrolidone carboxyl peptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyrrolidone-carboxyl peptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyrrolidone-carboxylate peptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyrrolidonecarboxylyl peptidase activity" EXACT [EC:3.4.19.3] +synonym: "pyrrolidonyl peptidase activity" EXACT [EC:3.4.19.3] +xref: EC:3.4.19.3 +xref: MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN +is_obsolete: true +consider: GO:0008234 +consider: GO:0016920 + +[Term] +id: GO:0004221 +name: obsolete ubiquitin thiolesterase activity +namespace: molecular_function +alt_id: GO:0008577 +def: "OBSOLETE. Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol." [EC:3.1.2.15, GOC:jh2] +comment: This term was made obsolete because this molecular function does not exist. +synonym: "ubiquitin C-terminal hydrolase activity" RELATED [] +synonym: "ubiquitin carboxy-terminal esterase activity" EXACT [EC:3.1.2.15] +synonym: "ubiquitin carboxy-terminal hydrolase activity" RELATED [EC:3.1.2.15] +synonym: "ubiquitin thioesterase activity" EXACT [EC:3.1.2.15] +synonym: "ubiquitin thiolesterase activity" EXACT [] +synonym: "ubiquitin-C-terminal-thioester hydrolase activity" EXACT [EC:3.1.2.15] +synonym: "ubiquitinyl hydrolase 1 activity" NARROW [] +xref: KEGG_REACTION:R02418 +xref: MetaCyc:UBIQUITIN-THIOLESTERASE-RXN +is_obsolete: true +consider: GO:0004843 +consider: GO:0036459 + +[Term] +id: GO:0004222 +name: metalloendopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] +synonym: "metalloendoprotease activity" NARROW [GOC:mah] +synonym: "metalloendoproteinase activity" NARROW [GOC:mah] +xref: EC:3.4.24 +xref: Reactome:R-HSA-1168777 "Metalloprotease cleavage of GHR" +xref: Reactome:R-HSA-1251992 "Cleavage of P-ERBB4jmA isoforms by ADAM17" +xref: Reactome:R-HSA-1299476 "MPP cleaves targeting peptide (presequence) of inner membrane precursors" +xref: Reactome:R-HSA-1299478 "MPP cleaves targeting peptide (presequence) of matrix precursors" +xref: Reactome:R-HSA-1454757 "Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13" +xref: Reactome:R-HSA-1454822 "Collagen type I degradation by MMP1,2,8,13, PRSS2" +xref: Reactome:R-HSA-1458433 "Collagen type I degradation by MMP14" +xref: Reactome:R-HSA-1474196 "Collagen type II degradation by MMP14" +xref: Reactome:R-HSA-1474210 "Collagen type III degradation by MMP14" +xref: Reactome:R-HSA-1474213 "Collagen type III degradation by MMP1,8,9,13" +xref: Reactome:R-HSA-1564112 "Collagen type VI degradation by MMP2,9,11" +xref: Reactome:R-HSA-1564117 "Collagen type XIV degradation by MMP9,13" +xref: Reactome:R-HSA-1564120 "Collagen type VII degradation by MMP1,2,3" +xref: Reactome:R-HSA-1564142 "Collagen type IV degradation by MMP2,3,4,9,10,12" +xref: Reactome:R-HSA-1564143 "Collagen type X degradation by MMP1,2" +xref: Reactome:R-HSA-1564164 "Collagen type V degradation by MMP2,9,10" +xref: Reactome:R-HSA-1564169 "Collagen type VIII degradation by MMP1" +xref: Reactome:R-HSA-1564179 "Collagen type XI degradation by MMP1,2,3,9" +xref: Reactome:R-HSA-1564184 "Collagen type IX degradation by MMP3,13" +xref: Reactome:R-HSA-1592310 "Aggrecan degradation by ADAMTSs" +xref: Reactome:R-HSA-1655851 "S2P hydrolyzes SREBP1A,1C,2" +xref: Reactome:R-HSA-177946 "Pro-EGF is cleaved to form mature EGF" +xref: Reactome:R-HSA-181567 "BoNT/C LC cleaves target cell STX1" +xref: Reactome:R-HSA-194793 "BoNT/C LC cleaves target cell SNAP25" +xref: Reactome:R-HSA-194796 "BoNT/B LC cleaves target cell VAMP2" +xref: Reactome:R-HSA-194800 "BoNT/E LC cleaves target cell SNAP25" +xref: Reactome:R-HSA-194808 "BoNT/F LC cleaves target cell VAMP1" +xref: Reactome:R-HSA-194809 "BoNT/D LC cleaves target cell VAMP1" +xref: Reactome:R-HSA-194818 "BoNT/A LC cleaves target cell SNAP25" +xref: Reactome:R-HSA-2002428 "Removal of fibrillar collagen N-propeptides" +xref: Reactome:R-HSA-2002440 "Removal of fibrillar collagen C-propeptides" +xref: Reactome:R-HSA-2022141 "Prolysyl oxidase activation" +xref: Reactome:R-HSA-2168046 "Collagen type XII degradation by MMP12" +xref: Reactome:R-HSA-2168982 "Collagen type XVI degradation by MMP9" +xref: Reactome:R-HSA-2179402 "Active MMP3 can cleave pro-HBEGF to form active HBEGF" +xref: Reactome:R-HSA-2473584 "Collagen type III degradation by MMP15" +xref: Reactome:R-HSA-2473594 "Collagen type II degradation by MMP15" +xref: Reactome:R-HSA-2473596 "Collagen type I degradation by MMP15" +xref: Reactome:R-HSA-2484882 "Collagen type X degradation by MMP3, 13" +xref: Reactome:R-HSA-2485111 "Collagen type III degradation by MMP10" +xref: Reactome:R-HSA-2485148 "Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13" +xref: Reactome:R-HSA-2514790 "Elastin degradation by MMP14" +xref: Reactome:R-HSA-2514831 "Fibrillin-1 degradation by MMP14" +xref: Reactome:R-HSA-2533874 "Laminin-511 degradation by MMP14" +xref: Reactome:R-HSA-2533944 "Fibronectin degradation by MMP10" +xref: Reactome:R-HSA-2533950 "Fibronectin degradation by MMP14, TMPRSS6" +xref: Reactome:R-HSA-2533965 "NID1 degradation by MMP14, MMP15" +xref: Reactome:R-HSA-2533970 "NID1 degradation by MMP3, 7" +xref: Reactome:R-HSA-2534240 "HSPG2 (perlecan) degradation by MMP14, MMP15" +xref: Reactome:R-HSA-2534248 "DCN (decorin) degradation by MMP2, MMP3, MMP7" +xref: Reactome:R-HSA-2537499 "Gelatin degradation by MMP19" +xref: Reactome:R-HSA-264758 "BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1" +xref: Reactome:R-HSA-3371385 "TNF-alpha is cleaved by ADAM17 (TACE)" +xref: Reactome:R-HSA-3788075 "Brevican degradation by ADAMTS4, ADAMTS5" +xref: Reactome:R-HSA-3791149 "Brevican degradation by MMP1, 2, 3, 7,8,10,13,19" +xref: Reactome:R-HSA-3791155 "Laminin-322 degradation by MMP14" +xref: Reactome:R-HSA-3791295 "Aggrecan degradation by MMP1,2,3,7,9,12,13" +xref: Reactome:R-HSA-3791319 "NID1 degradation by MMP19" +xref: Reactome:R-HSA-381435 "Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS" +xref: Reactome:R-HSA-381518 "PAAP-A proteolyzes IGF:IGFBP4" +xref: Reactome:R-HSA-381537 "PAPP-A2 proteolyzes IGF:IGFBP5:ALS" +xref: Reactome:R-HSA-3827958 "E-cadherin degradation by MMP9, KLK7" +xref: Reactome:R-HSA-3828025 "DCN (decorin) degradation by MMP14" +xref: Reactome:R-HSA-4086205 "OPN (osteopontin) degradation by MMP3, MMP7" +xref: Reactome:R-HSA-420818 "MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha)" +xref: Reactome:R-HSA-4224014 "E-cadherin degradation by ADAM10, ADAM15" +xref: Reactome:R-HSA-5228578 "TeNT LC cleaves target cell VAMP2" +xref: Reactome:R-HSA-5250606 "BoNT/D LC cleaves target cell VAMP2" +xref: Reactome:R-HSA-5250892 "BoNT/F LC cleaves target cell VAMP2" +xref: Reactome:R-HSA-5250962 "BoNT/G LC cleaves target cell VAMP2" +xref: Reactome:R-HSA-5250978 "BoNT/G LC cleaves target cell VAMP1" +xref: Reactome:R-HSA-5333671 "CLCAs self cleave" +xref: Reactome:R-HSA-5362793 "Hh-Np is cleaved by ADAM17 to promote ligand shedding" +xref: Reactome:R-HSA-5694082 "XK:KEL:Zn2+ cleaves EDN3" +xref: Reactome:R-HSA-6784620 "MBTPS1,2 cleaves CREB3L3 to CREB3L3(1-?) and CREB3L3(?-461)" +xref: Reactome:R-HSA-8867344 "OMA1 hydrolyses OPA1" +xref: Reactome:R-HSA-8874187 "MBTPS2 (S2P) cleaves CREB3L2" +xref: Reactome:R-HSA-8874192 "MBTPS2 (S2P) cleaves CREB3" +xref: Reactome:R-HSA-8874194 "MBTPS2 (S2P) cleaves CREB3L1" +xref: Reactome:R-HSA-8874195 "MBTPS2 (S2P) cleaves CREB3L4" +xref: Reactome:R-HSA-8874201 "MBTPS2 (S2P) cleaves CREB3L3" +xref: Reactome:R-HSA-8876868 "ECE1 cleaves EDN1(53-90)" +xref: Reactome:R-HSA-8877620 "ECE2 cleaves EDN1(53-90)" +xref: Reactome:R-HSA-8940554 "MMP2 cleaves OPTC" +xref: Reactome:R-HSA-8940561 "MMP7 cleaves OPTC" +xref: Reactome:R-HSA-8940641 "THOP1 cleaves oligopeptide fragment (8-16aa)" +xref: Reactome:R-HSA-8940959 "Neurolysin degrades neurotensin" +xref: Reactome:R-HSA-8942302 "MMP13 cleaves OPTC" +xref: Reactome:R-HSA-8943959 "MMP2, MMP9 cleave SCUBE3" +xref: Reactome:R-HSA-8949649 "PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE)" +xref: Reactome:R-HSA-8949659 "AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU" +xref: Reactome:R-HSA-8949668 "YME1L1 proteolyzes unassembled proSMDT1" +xref: Reactome:R-HSA-9624272 "MMPs cleave HB-EGF" +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0008237 ! metallopeptidase activity + +[Term] +id: GO:0004226 +name: obsolete Gly-X carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa." [EC:3.4.17.4] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase a" RELATED [EC:3.4.17.4] +synonym: "carboxypeptidase S activity" EXACT [EC:3.4.17.4] +synonym: "Gly-X carboxypeptidase activity" EXACT [] +synonym: "Gly-Xaa carboxypeptidase activity" EXACT [EC:3.4.17.4] +synonym: "glycine carboxypeptidase activity" EXACT [EC:3.4.17.4] +synonym: "peptidase alpha" RELATED [EC:3.4.17.4] +synonym: "yeast carboxypeptidase activity" EXACT [EC:3.4.17.4] +xref: EC:3.4.17.4 +xref: MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0004228 +name: obsolete gelatinase A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond." [EC:3.4.24.24] +comment: This term was made obsolete because it represents a gene product. +synonym: "3/4 collagenase activity" EXACT [EC:3.4.24.24] +synonym: "72 kDa gelatinase type A" RELATED [EC:3.4.24.24] +synonym: "72-kDa gelatinase activity" NARROW [EC:3.4.24.24] +synonym: "collagenase IV" RELATED [EC:3.4.24.24] +synonym: "collagenase type IV" RELATED [EC:3.4.24.24] +synonym: "gelatinase A activity" EXACT [] +synonym: "matrix metalloproteinase 2 activity" EXACT [EC:3.4.24.24] +synonym: "matrix metalloproteinase 5" RELATED [EC:3.4.24.24] +synonym: "MMP 2" RELATED [EC:3.4.24.24] +synonym: "MMP-2" EXACT [] +synonym: "type IV collagen metalloproteinase" BROAD [EC:3.4.24.24] +synonym: "type IV collagenase activity" EXACT [EC:3.4.24.24] +synonym: "type IV collagenase/gelatinase activity" EXACT [EC:3.4.24.24] +xref: EC:3.4.24.24 +xref: MetaCyc:3.4.24.24-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004229 +name: obsolete gelatinase B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of gelatin types I and V and collagen types IV and V." [EC:3.4.24.35] +comment: This term was made obsolete because it represents a gene product. +synonym: "92-kDa gelatinase activity" NARROW [EC:3.4.24.35] +synonym: "92-kDa type IV collagenase activity" NARROW [EC:3.4.24.35] +synonym: "95 kDa type IV collagenase/gelatinase activity" EXACT [EC:3.4.24.35] +synonym: "collagenase IV" RELATED [EC:3.4.24.35] +synonym: "collagenase type IV" RELATED [EC:3.4.24.35] +synonym: "gelatinase B activity" EXACT [] +synonym: "gelatinase MMP 9" RELATED [EC:3.4.24.35] +synonym: "macrophage gelatinase activity" NARROW [EC:3.4.24.35] +synonym: "matrix metalloproteinase 9 activity" EXACT [EC:3.4.24.35] +synonym: "MMP 9" RELATED [EC:3.4.24.35] +synonym: "MMP-9" EXACT [] +synonym: "type IV collagen metalloproteinase" BROAD [EC:3.4.24.35] +synonym: "type V collagenase activity" EXACT [EC:3.4.24.35] +xref: EC:3.4.24.35 +xref: MetaCyc:3.4.24.35-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004230 +name: obsolete glutamyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide." [EC:3.4.11.7] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminopeptidase A" RELATED [EC:3.4.11.7] +synonym: "angiotensinase A" RELATED [EC:3.4.11.7] +synonym: "angiotensinase A2" RELATED [EC:3.4.11.7] +synonym: "antigen BP-1/6C3 of mouse B lymphocytes" RELATED [EC:3.4.11.7] +synonym: "aspartate aminopeptidase activity" EXACT [EC:3.4.11.7] +synonym: "Ca2+-activated glutamate aminopeptidase activity" EXACT [EC:3.4.11.7] +synonym: "glutamyl aminopeptidase activity" EXACT [] +synonym: "glutamyl peptidase activity" EXACT [EC:3.4.11.7] +synonym: "L-aspartate aminopeptidase activity" EXACT [EC:3.4.11.7] +synonym: "membrane aminopeptidase II" RELATED [EC:3.4.11.7] +xref: EC:3.4.11.7 +xref: MetaCyc:3.4.11.7-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0004231 +name: obsolete insulysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins." [EC:3.4.24.56] +comment: This term was made obsolete because it represents a gene product. +synonym: "IDE" RELATED [EC:3.4.24.56] +synonym: "insulin protease activity" EXACT [EC:3.4.24.56] +synonym: "insulin proteinase activity" EXACT [EC:3.4.24.56] +synonym: "insulin-degrading enzyme activity" EXACT [EC:3.4.24.56] +synonym: "insulin-degrading neutral proteinase activity" EXACT [EC:3.4.24.56] +synonym: "insulin-glucagon protease activity" EXACT [EC:3.4.24.56] +synonym: "insulin-specific protease activity" EXACT [EC:3.4.24.56] +synonym: "insulinase activity" EXACT [EC:3.4.24.56] +synonym: "insulysin activity" EXACT [] +synonym: "metalloinsulinase activity" EXACT [EC:3.4.24.56] +xref: EC:3.4.24.56 +xref: MetaCyc:3.4.24.56-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004232 +name: obsolete interstitial collagenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue." [EC:3.4.24.7] +comment: This term was made obsolete because it represents a gene product. +synonym: "interstitial collagenase activity" EXACT [] +synonym: "matrix metalloproteinase 1" EXACT [] +synonym: "MMP-1" EXACT [] +synonym: "vertebrate collagenase activity" EXACT [EC:3.4.24.7] +xref: EC:3.4.24.7 +xref: MetaCyc:3.4.24.7-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004234 +name: obsolete macrophage elastase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin." [EC:3.4.24.65] +comment: This term was made obsolete because it represents a gene product. +synonym: "human macrophage metalloelastase (HME)" EXACT [EC:3.4.24.65] +synonym: "macrophage elastase activity" EXACT [] +synonym: "matrix metalloproteinase 12 activity" EXACT [EC:3.4.24.65] +synonym: "metalloelastase activity" EXACT [EC:3.4.24.65] +synonym: "metalloesterase activity" EXACT [] +synonym: "MMP-12" EXACT [] +xref: EC:3.4.24.65 +xref: MetaCyc:3.4.24.65-RXN +is_obsolete: true +consider: GO:0004175 +consider: GO:0004222 + +[Term] +id: GO:0004235 +name: obsolete matrilysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I)." [EC:3.4.24.23] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrilysin activity" EXACT [] +synonym: "matrin activity" EXACT [EC:3.4.24.23] +synonym: "matrix metalloproteinase 7 activity" EXACT [EC:3.4.24.23] +synonym: "matrix metalloproteinase pump 1" RELATED [EC:3.4.24.23] +synonym: "metalloproteinase pump-1" RELATED [EC:3.4.24.23] +synonym: "MMP" RELATED [EC:3.4.24.23] +synonym: "MMP 7" RELATED [EC:3.4.24.23] +synonym: "MMP-7" EXACT [] +synonym: "PUMP" RELATED [EC:3.4.24.23] +synonym: "PUMP-1 activity" NARROW [EC:3.4.24.23] +synonym: "PUMP-1 proteinase activity" EXACT [EC:3.4.24.23] +synonym: "putative (or punctuated) metalloproteinase-1 activity" NARROW [EC:3.4.24.23] +synonym: "putative metalloproteinase activity" EXACT [EC:3.4.24.23] +synonym: "uterine metalloendopeptidase activity" NARROW [EC:3.4.24.23] +xref: EC:3.4.24.23 +xref: MetaCyc:3.4.24.23-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004237 +name: obsolete membrane dipeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of dipeptides." [EC:3.4.13.19] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminodipeptidase activity" EXACT [EC:3.4.13.19] +synonym: "dehydropeptidase I (DPH I)" RELATED [EC:3.4.13.19] +synonym: "dehydropeptidase I activity" EXACT [EC:3.4.13.19] +synonym: "dipeptide hydrolase" BROAD [EC:3.4.13.19] +synonym: "dipeptidyl hydrolase activity" EXACT [EC:3.4.13.19] +synonym: "DPH I activity" NARROW [EC:3.4.13.19] +synonym: "glycosyl-phosphatidylinositol-anchored renal dipeptidase activity" EXACT [EC:3.4.13.19] +synonym: "MDP" RELATED [EC:3.4.13.19] +synonym: "membrane dipeptidase activity" EXACT [] +synonym: "microsomal dipeptidase activity" NARROW [EC:3.4.13.19] +synonym: "nonspecific dipeptidase activity" EXACT [EC:3.4.13.19] +synonym: "renal dipeptidase activity" NARROW [EC:3.4.13.19] +xref: EC:3.4.13.19 +xref: MetaCyc:3.4.13.19-RXN +is_obsolete: true +consider: GO:0008235 +consider: GO:0016805 + +[Term] +id: GO:0004238 +name: obsolete meprin A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues." [EC:3.4.24.18] +comment: This term was made obsolete because it represents a gene product. +synonym: "endopeptidase-2 activity" BROAD [EC:3.4.24.18] +synonym: "meprin" RELATED [EC:3.4.24.18] +synonym: "meprin A activity" EXACT [] +synonym: "meprin-a" RELATED [EC:3.4.24.18] +synonym: "N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity" EXACT [EC:3.4.24.18] +synonym: "PABA-peptide hydrolase activity" EXACT [EC:3.4.24.18] +synonym: "PPH" RELATED [EC:3.4.24.18] +xref: EC:3.4.24.18 +xref: MetaCyc:3.4.24.18-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004239 +name: obsolete methionyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides." [EC:3.4.11.18] +comment: This term was made obsolete because it represents a gene product. +synonym: "L-methionine aminopeptidase activity" EXACT [EC:3.4.11.18] +synonym: "MAP" RELATED [EC:3.4.11.18] +synonym: "methionine aminopeptidase activity" EXACT [EC:3.4.11.18] +synonym: "methionyl aminopeptidase activity" EXACT [] +synonym: "peptidase M activity" EXACT [EC:3.4.11.18] +xref: EC:3.4.11.18 +xref: MetaCyc:3.4.11.18-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 +consider: GO:0070084 + +[Term] +id: GO:0004240 +name: obsolete mitochondrial processing peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2." [EC:3.4.24.64] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-mitochondrial processing peptidase" NARROW [] +synonym: "beta-mitochondrial processing peptidase" NARROW [] +synonym: "matrix peptidase" RELATED [EC:3.4.24.64] +synonym: "matrix processing peptidase" RELATED [EC:3.4.24.64] +synonym: "matrix processing proteinase" RELATED [EC:3.4.24.64] +synonym: "mitochondrial processing peptidase activity" EXACT [] +synonym: "mitochondrial protein precursor-processing proteinase activity" EXACT [EC:3.4.24.64] +synonym: "MPP" EXACT [] +synonym: "processing enhancing peptidase (for one of two subunits)" RELATED [EC:3.4.24.64] +synonym: "processing enhancing peptidase activity" NARROW [EC:3.4.24.64] +xref: EC:3.4.24.64 +xref: MetaCyc:3.4.24.64-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004241 +name: obsolete alpha-mitochondrial processing peptidase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-mitochondrial processing peptidase" EXACT [] +synonym: "alpha-MPP" EXACT [] +is_obsolete: true +consider: GO:0004222 +consider: GO:0005739 + +[Term] +id: GO:0004242 +name: obsolete beta-mitochondrial processing peptidase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "beta-mitochondrial processing peptidase" EXACT [] +synonym: "beta-MPP" EXACT [] +is_obsolete: true +consider: GO:0004222 +consider: GO:0005739 + +[Term] +id: GO:0004243 +name: obsolete mitochondrial intermediate peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion." [EC:3.4.24.59] +comment: This term was made obsolete because it represents a gene product. +synonym: "MIP" BROAD [] +synonym: "mitochondrial intermediate peptidase activity" EXACT [] +synonym: "mitochondrial intermediate precursor-processing proteinase activity" EXACT [EC:3.4.24.59] +xref: EC:3.4.24.59 +xref: MetaCyc:3.4.24.59-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004244 +name: obsolete mitochondrial inner membrane peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space." [PMID:12191769] +comment: This term was made obsolete because it represents a gene product. +synonym: "IMP" BROAD [] +synonym: "mitochondrial inner membrane peptidase activity" EXACT [] +xref: EC:3.4.99 +is_obsolete: true +replaced_by: GO:0004175 + +[Term] +id: GO:0004245 +name: obsolete neprilysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides." [EC:3.4.24.11] +comment: This term was made obsolete because it represents a gene product. +synonym: "acute lymphoblastic leukemia antigen" RELATED [EC:3.4.24.11] +synonym: "CALLA" RELATED [EC:3.4.24.11] +synonym: "CALLA (common acute lymphoblastic leukemia-associated) antigens" RELATED [EC:3.4.24.11] +synonym: "CALLA antigen" RELATED [EC:3.4.24.11] +synonym: "CALLA glycoprotein" RELATED [EC:3.4.24.11] +synonym: "CALLA glycoproteins" RELATED [EC:3.4.24.11] +synonym: "CD10" RELATED [EC:3.4.24.11] +synonym: "common acute lymphoblastic leukemia antigen" RELATED [EC:3.4.24.11] +synonym: "common acute lymphoblastic leukemia-associated antigens" RELATED [EC:3.4.24.11] +synonym: "endopeptidase 24.11" RELATED [EC:3.4.24.11] +synonym: "endopeptidase-2 activity" BROAD [EC:3.4.24.11] +synonym: "enkephalinase activity" EXACT [EC:3.4.24.11] +synonym: "kidney-brush-border neutral endopeptidase" NARROW [EC:3.4.24.11] +synonym: "kidney-brush-border neutral peptidase" NARROW [EC:3.4.24.11] +synonym: "kidney-brush-border neutral proteinase activity" NARROW [EC:3.4.24.11] +synonym: "membrane metalloendopeptidase activity" NARROW [EC:3.4.24.11] +synonym: "neprilysin activity" EXACT [] +synonym: "neutral endopeptidase 24.11" RELATED [EC:3.4.24.11] +synonym: "neutral endopeptidase activity" EXACT [EC:3.4.24.11] +synonym: "neutral metallendopeptidase activity" EXACT [EC:3.4.24.11] +xref: EC:3.4.24.11 +xref: MetaCyc:3.4.24.11-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004246 +name: obsolete peptidyl-dipeptidase A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II." [EC:3.4.15.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "ACE activity" BROAD [] +synonym: "angiotensin converting enzyme" RELATED [EC:3.4.15.1] +synonym: "angiotensin I-converting enzyme activity" EXACT [EC:3.4.15.1] +synonym: "carboxycathepsin activity" EXACT [EC:3.4.15.1] +synonym: "DCP" RELATED [EC:3.4.15.1] +synonym: "dipeptide hydrolase" BROAD [EC:3.4.15.1] +synonym: "dipeptidyl carboxypeptidase I activity" EXACT [EC:3.4.15.1] +synonym: "endothelial cell peptidyl dipeptidase activity" EXACT [EC:3.4.15.1] +synonym: "kininase II activity" EXACT [EC:3.4.15.1] +synonym: "PDH" RELATED [EC:3.4.15.1] +synonym: "peptidase P activity" EXACT [EC:3.4.15.1] +synonym: "peptidyl dipeptidase A" RELATED [EC:3.4.15.1] +synonym: "peptidyl dipeptidase I activity" EXACT [EC:3.4.15.1] +synonym: "peptidyl dipeptidase-4" RELATED [EC:3.4.15.1] +synonym: "peptidyl dipeptide hydrolase activity" EXACT [EC:3.4.15.1] +synonym: "peptidyl-dipeptidase A activity" EXACT [] +synonym: "peptidyl-dipeptide hydrolase activity" EXACT [EC:3.4.15.1] +synonym: "peptidyldipeptide hydrolase activity" EXACT [EC:3.4.15.1] +xref: EC:3.4.15.1 +xref: MetaCyc:3.4.15.1-RXN +is_obsolete: true +consider: GO:0008237 +consider: GO:0008241 + +[Term] +id: GO:0004247 +name: obsolete saccharolysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds." [EC:3.4.24.37] +comment: This term was made obsolete because it represents a gene product. +synonym: "oligopeptidase yscD activity" NARROW [EC:3.4.24.37] +synonym: "proteinase yscD activity" NARROW [EC:3.4.24.37] +synonym: "saccharolysin activity" EXACT [] +synonym: "saccharomyces cerevisiae proteinase yscD" RELATED [EC:3.4.24.37] +synonym: "yeast cysteine proteinase D activity" NARROW [EC:3.4.24.37] +xref: EC:3.4.24.37 +xref: MetaCyc:3.4.24.37-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004248 +name: obsolete stromelysin 1 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues." [EC:3.4.24.17] +comment: This term was made obsolete because it represents a gene product. +synonym: "collagen-activating protein" RELATED [EC:3.4.24.17] +synonym: "collagenase activating protein" RELATED [EC:3.4.24.17] +synonym: "matrix metalloproteinase 3 activity" EXACT [EC:3.4.24.17] +synonym: "MMP-3" EXACT [] +synonym: "neutral proteoglycanase activity" EXACT [EC:3.4.24.17] +synonym: "procollagenase activator" RELATED [EC:3.4.24.17] +synonym: "proteoglycanase activity" EXACT [EC:3.4.24.17] +synonym: "stromelysin" RELATED [EC:3.4.24.17] +synonym: "stromelysin 1 activity" EXACT [] +synonym: "transin activity" EXACT [EC:3.4.24.17] +xref: EC:3.4.24.17 +xref: MetaCyc:3.4.24.17-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004249 +name: obsolete stromelysin 3 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrix metalloproteinase 11" EXACT [] +synonym: "MMP-11" EXACT [] +synonym: "stromelysin 3 activity" EXACT [] +xref: EC:3.4.24 +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0004250 +name: obsolete aminopeptidase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates." [EC:3.4.11.22] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminopeptidase I activity" EXACT [] +synonym: "aminopeptidase III activity" EXACT [EC:3.4.11.22] +synonym: "aminopeptidase yscI activity" NARROW [EC:3.4.11.22] +synonym: "leucine aminopeptidase IV activity" EXACT [EC:3.4.11.22] +synonym: "vacuolar aminopeptidase I activity" NARROW [EC:3.4.11.22] +synonym: "yeast aminopeptidase I" RELATED [EC:3.4.11.22] +xref: EC:3.4.11.22 +xref: MetaCyc:3.4.11.22-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0004251 +name: obsolete X-Pro dipeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro." [EC:3.4.13.9] +comment: This term was made obsolete because it represents a gene product. +synonym: "gamma-peptidase activity" EXACT [EC:3.4.13.9] +synonym: "imidodipeptidase activity" EXACT [EC:3.4.13.9] +synonym: "peptidase D" RELATED [EC:3.4.13.9] +synonym: "prolidase activity" EXACT [EC:3.4.13.9] +synonym: "proline dipeptidase activity" EXACT [EC:3.4.13.9] +synonym: "X-Pro dipeptidase activity" EXACT [] +synonym: "Xaa-Pro dipeptidase activity" EXACT [] +xref: EC:3.4.13.9 +xref: MetaCyc:3.4.13.9-RXN +is_obsolete: true +consider: GO:0008235 +consider: GO:0016805 + +[Term] +id: GO:0004252 +name: serine-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094] +subset: goslim_chembl +synonym: "blood coagulation factor activity" RELATED [] +synonym: "serine elastase activity" RELATED [GOC:krc] +xref: EC:3.4.21 +xref: Reactome:R-HSA-114697 "Thrombin-mediated activation of Proteinase-activated receptors" +xref: Reactome:R-HSA-1181152 "Cleavage of NODAL proprotein" +xref: Reactome:R-HSA-139893 "Granzyme-B activates BID by cleavage" +xref: Reactome:R-HSA-140599 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides" +xref: Reactome:R-HSA-140664 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)" +xref: Reactome:R-HSA-140696 "factor V -> factor Va + factor V activation peptide" +xref: Reactome:R-HSA-140700 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)" +xref: Reactome:R-HSA-140736 "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)" +xref: Reactome:R-HSA-140769 "factor VII -> factor VIIa" +xref: Reactome:R-HSA-140777 "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)" +xref: Reactome:R-HSA-140823 "factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)" +xref: Reactome:R-HSA-140840 "fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B" +xref: Reactome:R-HSA-140870 "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin" +xref: Reactome:R-HSA-141026 "Activated protein C cleaves factor Va to factor Vi intermediate form" +xref: Reactome:R-HSA-141040 "Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C" +xref: Reactome:R-HSA-1454843 "E-cadherin degradation by MMP3, MMP7 and plasmin." +xref: Reactome:R-HSA-1474197 "Collagen type II degradation by MMP1,3,8,13,PRSS2" +xref: Reactome:R-HSA-1566962 "Elastin degradation by elastin-degrading extracellular proteinases" +xref: Reactome:R-HSA-1566979 "Laminin-332 degradation by laminin-322 degrading extracellular proteinases" +xref: Reactome:R-HSA-1566981 "Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS" +xref: Reactome:R-HSA-158137 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer" +xref: Reactome:R-HSA-158164 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst)" +xref: Reactome:R-HSA-158300 "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst)" +xref: Reactome:R-HSA-158311 "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin" +xref: Reactome:R-HSA-158313 "factor XII -> factor XIIa" +xref: Reactome:R-HSA-158333 "factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst)" +xref: Reactome:R-HSA-158419 "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)" +xref: Reactome:R-HSA-158744 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin" +xref: Reactome:R-HSA-158747 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)" +xref: Reactome:R-HSA-158750 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin" +xref: Reactome:R-HSA-158766 "fibrin multimer, crosslinked -> fibrin digestion products (plasmin)" +xref: Reactome:R-HSA-158925 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst)" +xref: Reactome:R-HSA-158942 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR" +xref: Reactome:R-HSA-158982 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst)" +xref: Reactome:R-HSA-1592270 "NID1 degradation by MMP1, 9, 12, ELANE" +xref: Reactome:R-HSA-1592278 "Autocatalytic activation of proMMP2" +xref: Reactome:R-HSA-1592297 "Full activation of MMP1" +xref: Reactome:R-HSA-1592314 "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)" +xref: Reactome:R-HSA-1592316 "Initial activation of proMMP1" +xref: Reactome:R-HSA-1592362 "Activation of proMMP7 by MMP3" +xref: Reactome:R-HSA-1592371 "Initial activation of proMMP3" +xref: Reactome:R-HSA-1592398 "Activation of proMMP8" +xref: Reactome:R-HSA-1592436 "Initial activation of proMMP9 by MMPs" +xref: Reactome:R-HSA-159728 "Furin cleaves pro-prothrombin to prothrombin" +xref: Reactome:R-HSA-159733 "Furin cleaves pro-factor X to factor X" +xref: Reactome:R-HSA-159771 "Furin cleaves pro-protein C to protein C" +xref: Reactome:R-HSA-159773 "Furin cleaves pro-protein S to protein S" +xref: Reactome:R-HSA-159796 "Furin cleaves pro-factor IX to factor IX" +xref: Reactome:R-HSA-159868 "Furin cleaves pro-factor VII to factor VII" +xref: Reactome:R-HSA-1602458 "Activation of proMMP10" +xref: Reactome:R-HSA-1602466 "Activation of MT-MMPs by FURIN" +xref: Reactome:R-HSA-1602473 "Autocatalytic activation of MMP1" +xref: Reactome:R-HSA-1602484 "Activation of proMMP11 by FURIN" +xref: Reactome:R-HSA-1602488 "Initial activation of proMMP13 by plasmin and trypsin" +xref: Reactome:R-HSA-1604359 "Initial activation of proMMP2 by MMP1, 7" +xref: Reactome:R-HSA-1604360 "Initial activation of proMMP2 by MMP14" +xref: Reactome:R-HSA-1604368 "Autocatalytic activation of bound proMMP2" +xref: Reactome:R-HSA-1604690 "Activation of MMP9 intermediate form by MMPs" +xref: Reactome:R-HSA-1604712 "Initial activation of proMMP7 by trypsin" +xref: Reactome:R-HSA-1604722 "Activation of proMMP9 by proteases" +xref: Reactome:R-HSA-1604731 "Autocatalytic activation of MMP3" +xref: Reactome:R-HSA-1604732 "Autocatalytic activation of proMMP13" +xref: Reactome:R-HSA-1604741 "Initial activation of proMMP13 by MMP14 (MT1-MMP)" +xref: Reactome:R-HSA-1604752 "Initial activation of proMMP13 by MMP3" +xref: Reactome:R-HSA-1604763 "Autocatalytic activation of MMP7" +xref: Reactome:R-HSA-163798 "Furin cleaves pro-protein Z to protein Z" +xref: Reactome:R-HSA-163843 "Furin cleaves pro-GAS6 to GAS6" +xref: Reactome:R-HSA-1655842 "S1P hydrolyzes SREBP1A,1C,2" +xref: Reactome:R-HSA-166753 "Conversion of C4 into C4a and C4b" +xref: Reactome:R-HSA-166792 "Conversion of C2 into C2a and C2b" +xref: Reactome:R-HSA-166817 "Cleavage of C3 by C3 convertases" +xref: Reactome:R-HSA-170844 "Latent TGF-beta-1 is cleaved by furin" +xref: Reactome:R-HSA-171288 "Cleavage of the viral Env gp160 precursor polyprotein" +xref: Reactome:R-HSA-173626 "Activation of C1r" +xref: Reactome:R-HSA-173631 "Activation of C1s" +xref: Reactome:R-HSA-173680 "Activation of C5" +xref: Reactome:R-HSA-173745 "Factor D cleaves C3(H2O)-bound Factor B" +xref: Reactome:R-HSA-174551 "Formation of alternative pathway C5 convertase" +xref: Reactome:R-HSA-1799329 "Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein" +xref: Reactome:R-HSA-183122 "Factor D cleaves C3b-bound Factor B" +xref: Reactome:R-HSA-183130 "C3(H2O):Factor Bb cleaves C3 to C3b and C3a" +xref: Reactome:R-HSA-186785 "PDGF-AA clevage by Furin" +xref: Reactome:R-HSA-187020 "Part of pro-beta-NGF is processed to mature beta-NGF" +xref: Reactome:R-HSA-1912369 "NOTCH precursor cleaved to form mature NOTCH" +xref: Reactome:R-HSA-1912372 "Fringe-modified Pre-NOTCH is cleaved by FURIN" +xref: Reactome:R-HSA-2022411 "Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)" +xref: Reactome:R-HSA-2129357 "Fibrillin C-terminal processing" +xref: Reactome:R-HSA-2168923 "Collagen type XVIII endostatin release" +xref: Reactome:R-HSA-2168960 "Collagen type XVII ectodomain shedding" +xref: Reactome:R-HSA-2172405 "Collagen type XXIII ectodomain shedding" +xref: Reactome:R-HSA-2214330 "Cleavage of collagen VII NC2 region by BMP1" +xref: Reactome:R-HSA-2471621 "Endostatin degradation by cathepsins" +xref: Reactome:R-HSA-2471842 "Collagen type XXV ectomain shedding" +xref: Reactome:R-HSA-2482180 "Collagen type VIII degradation by ELANE" +xref: Reactome:R-HSA-2514772 "Fibrillin-1 degradation by MMP3, CTSK, CTSL2" +xref: Reactome:R-HSA-2514823 "Fibrillin-1 degradation by ELANE" +xref: Reactome:R-HSA-2534160 "HSPG2 (perlecan) degradation by MMP13, CTSS" +xref: Reactome:R-HSA-2534206 "E-cadherin degradation by PS1:NCSTN (Gamma-secretase)" +xref: Reactome:R-HSA-2534260 "E-cadherin degradation by caspase-3 and calpain-1" +xref: Reactome:R-HSA-265301 "Corticotropin cleavage from POMC" +xref: Reactome:R-HSA-3266557 "Factor I cleaves iC3b" +xref: Reactome:R-HSA-3785684 "Fibronectin degradation by CTSG" +xref: Reactome:R-HSA-3788061 "Fibronectin degradation by ADAM8" +xref: Reactome:R-HSA-381135 "MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha)" +xref: Reactome:R-HSA-381446 "Thrombin proteolyzes IGF:IGFBP3:ALS" +xref: Reactome:R-HSA-381461 "Plasmin proteolyzes IGF:IGFBP-3:ALS" +xref: Reactome:R-HSA-381466 "Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS" +xref: Reactome:R-HSA-3814820 "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1" +xref: Reactome:R-HSA-381500 "Cathepsin G proteolyzes IGF:IGFBP3:ALS" +xref: Reactome:R-HSA-381798 "PCSK1 hydrolyzes Proglucagon to Glucagon-like Peptide-1" +xref: Reactome:R-HSA-382061 "Extracellular processing of novel PDGFs" +xref: Reactome:R-HSA-3928657 "MMP2,9 cleave EPHB" +xref: Reactome:R-HSA-400459 "Signal peptidase hydrolyzes preproGLP-1 to proGLP-1" +xref: Reactome:R-HSA-400492 "PCSK1 hydrolyzes proGIP to GIP" +xref: Reactome:R-HSA-400496 "Signal peptidase hydrolyzes preproGIP to proGIP" +xref: Reactome:R-HSA-422021 "PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin" +xref: Reactome:R-HSA-422051 "Cleavage of the signal peptide of Preproghrelin" +xref: Reactome:R-HSA-5210912 "Furin cleaves ANTXR2-bound PA83 to yield PA63" +xref: Reactome:R-HSA-5210935 "Furin cleaves ANTXR1-bound PA83 to yield PA63" +xref: Reactome:R-HSA-5578783 "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)" +xref: Reactome:R-HSA-5591040 "Activated protein C cleaves Factor Va intermediate form for Factor Va" +xref: Reactome:R-HSA-5607002 "Activated protein C cleaves factor VIIIa" +xref: Reactome:R-HSA-5691512 "APEH hydrolyses NAc-Ser-protein" +xref: Reactome:R-HSA-6800198 "HPN heterodimer cleaves pro-MST1 to form MST1 dimer" +xref: Reactome:R-HSA-6800200 "HPN heterodimer cleaves pro-HGF to form HGF dimer" +xref: Reactome:R-HSA-6800299 "HGFAC cleaves pro-HGF to form HGF dimer" +xref: Reactome:R-HSA-6801687 "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)" +xref: Reactome:R-HSA-6807224 "Furin cleaves pro-BGLAP to BGLAP" +xref: Reactome:R-HSA-8849826 "ST14 hydrolyzes and activates KLK5" +xref: Reactome:R-HSA-8849857 "KLK5 cleaves and activates CELA2" +xref: Reactome:R-HSA-8850831 "KLK5 cleaves and activates KLK8" +xref: Reactome:R-HSA-8852716 "Thrombin, ELANE cleave C5" +xref: Reactome:R-HSA-8855825 "HTRA1 hydrolyzes ACAN (Aggrecan)" +xref: Reactome:R-HSA-8865275 "PDGF-BB clevage by Furin" +xref: Reactome:R-HSA-8865276 "PDGF-AB clevage by Furin" +xref: Reactome:R-HSA-8874186 "MBTPS1 (S1P) cleaves CREB3L4" +xref: Reactome:R-HSA-8874204 "MBTPS1 (S1P) cleaves CREB3" +xref: Reactome:R-HSA-8874205 "MBTPS1 (S1P) cleaves CREB3L2" +xref: Reactome:R-HSA-8874206 "MBTPS1 (S1P) cleaves CREB3L3" +xref: Reactome:R-HSA-8874212 "MBTPS1 (S1P) cleaves CREB3L1" +xref: Reactome:R-HSA-9023178 "PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89))" +xref: Reactome:R-HSA-9023196 "PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110)" +xref: Reactome:R-HSA-9023626 "DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)" +xref: Reactome:R-HSA-9023627 "DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)" +xref: Reactome:R-HSA-9023632 "DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1)" +xref: Reactome:R-HSA-9023633 "DPP4(1-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1)" +xref: Reactome:R-HSA-9033490 "TYSND1 cleaves PHYH" +xref: Reactome:R-HSA-9033506 "TYSND1 cleaves AGPS" +xref: Reactome:R-HSA-9033515 "TYSND1 cleaves ACOX1" +xref: Reactome:R-HSA-9033520 "TYSND1 cleaves TYSND1" +xref: Reactome:R-HSA-9033524 "TYSND1 cleaves SCP2" +xref: Reactome:R-HSA-9033529 "TYSND1 cleaves ACAA1" +xref: Reactome:R-HSA-9033530 "TYSND1 cleaves HSD17B4" +xref: Reactome:R-HSA-976743 "Factor I inactivates plasma Factor H-bound C3b" +xref: Reactome:R-HSA-977371 "Factor I inactivates Factor H-boundC3b" +xref: Reactome:R-HSA-977615 "Factor I inactivates MCP/CR1-bound C4b/C3b" +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0008236 ! serine-type peptidase activity + +[Term] +id: GO:0004253 +name: obsolete gamma-renin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide." [EC:3.4.21.54] +comment: This term was made obsolete because it represents a gene product. +synonym: "gamma-renin activity" EXACT [] +xref: EC:3.4.21.54 +xref: MetaCyc:3.4.21.54-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004254 +name: obsolete acylaminoacyl-peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide." [EC:3.4.19.1] +synonym: "acylamino-acid-releasing enzyme activity" EXACT [EC:3.4.19.1] +synonym: "acylaminoacyl-peptidase activity" EXACT [] +synonym: "alpha-N-acylpeptide hydrolase activity" EXACT [EC:3.4.19.1] +synonym: "N-acylpeptide hydrolase activity" EXACT [EC:3.4.19.1] +synonym: "N-formylmethionine (fMet) aminopeptidase activity" EXACT [EC:3.4.19.1] +xref: EC:3.4.19.1 +xref: MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004258 +name: obsolete vacuolar carboxypeptidase Y +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity." [EC:3.4.16.5] +comment: This term was made obsolete because it contains both component and function information. +synonym: "vacuolar carboxypeptidase Y" EXACT [] +is_obsolete: true +consider: GO:0004185 +consider: GO:0005773 + +[Term] +id: GO:0004261 +name: obsolete cathepsin G activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C." [EC:3.4.21.20] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin G activity" EXACT [] +synonym: "chymotrypsin-like proteinase activity" EXACT [EC:3.4.21.20] +synonym: "neutral proteinase activity" EXACT [EC:3.4.21.20] +xref: EC:3.4.21.20 +xref: MetaCyc:3.4.21.20-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004262 +name: obsolete cerevisin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides." [EC:3.4.21.48] +comment: This term was made obsolete because it represents a gene product. +synonym: "baker's yeast proteinase B" RELATED [EC:3.4.21.48] +synonym: "brewer's yeast proteinase" NARROW [EC:3.4.21.48] +synonym: "cerevisin activity" EXACT [] +synonym: "peptidase beta" RELATED [EC:3.4.21.48] +synonym: "proteinase yscB activity" NARROW [EC:3.4.21.48] +synonym: "yeast proteinase B activity" NARROW [EC:3.4.21.48] +xref: EC:3.4.21.48 +xref: MetaCyc:3.4.21.48-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004263 +name: obsolete chymotrypsin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa." [EC:3.4.21.1, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-chymar" RELATED [EC:3.4.21.1] +synonym: "alpha-chymar ophth" RELATED [EC:3.4.21.1] +synonym: "alpha-chymotrypsin A" RELATED [EC:3.4.21.1] +synonym: "alpha-chymotrypsin activity" NARROW [EC:3.4.21.1] +synonym: "avazyme" RELATED [EC:3.4.21.1] +synonym: "chymar" RELATED [EC:3.4.21.1] +synonym: "chymotest" RELATED [EC:3.4.21.1] +synonym: "chymotrypsin A activity" NARROW [EC:3.4.21.1] +synonym: "chymotrypsin activity" EXACT [] +synonym: "chymotrypsin B activity" NARROW [EC:3.4.21.1] +synonym: "chymotrypsins A and B" RELATED [EC:3.4.21.1] +synonym: "enzeon" RELATED [EC:3.4.21.1] +synonym: "quimar" RELATED [EC:3.4.21.1] +synonym: "quimotrase activity" EXACT [EC:3.4.21.1] +xref: EC:3.4.21.1 +xref: MetaCyc:3.4.21.1-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004274 +name: obsolete dipeptidyl-peptidase IV activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline." [EC:3.4.14.5] +comment: This term was made obsolete because it represents a gene product. +synonym: "amino acyl-prolyl dipeptidyl aminopeptidase activity" EXACT [EC:3.4.14.5] +synonym: "dipeptidyl aminopeptidase IV activity" EXACT [EC:3.4.14.5] +synonym: "dipeptidyl peptidase IV" RELATED [EC:3.4.14.5] +synonym: "dipeptidyl-aminopeptidase IV" RELATED [EC:3.4.14.5] +synonym: "dipeptidyl-peptidase IV activity" EXACT [] +synonym: "dipeptidyl-peptide hydrolase activity" EXACT [EC:3.4.14.5] +synonym: "DPP IV activity" EXACT [EC:3.4.14.5] +synonym: "DPP IV/CD26" RELATED [EC:3.4.14.5] +synonym: "Gly-Pro naphthylamidase activity" EXACT [EC:3.4.14.5] +synonym: "glycoprotein GP110" RELATED [EC:3.4.14.5] +synonym: "glycylproline aminopeptidase activity" EXACT [EC:3.4.14.5] +synonym: "glycylprolyl aminopeptidase activity" EXACT [EC:3.4.14.5] +synonym: "glycylprolyl dipeptidylaminopeptidase activity" EXACT [EC:3.4.14.5] +synonym: "leukocyte antigen CD26" RELATED [EC:3.4.14.5] +synonym: "lymphocyte antigen CD26" RELATED [EC:3.4.14.5] +synonym: "pep X" RELATED [EC:3.4.14.5] +synonym: "post-proline dipeptidyl aminopeptidase IV activity" EXACT [EC:3.4.14.5] +synonym: "postproline dipeptidyl aminopeptidase IV" RELATED [EC:3.4.14.5] +synonym: "T cell triggering molecule Tp103" RELATED [EC:3.4.14.5] +synonym: "X-PDAP" RELATED [EC:3.4.14.5] +synonym: "Xaa-Pro-dipeptidyl-aminopeptidase activity" EXACT [EC:3.4.14.5] +synonym: "Xaa-Pro-dipeptidylaminopeptidase activity" EXACT [EC:3.4.14.5] +xref: EC:3.4.14.5 +xref: MetaCyc:3.4.14.5-RXN +is_obsolete: true +consider: GO:0008236 +consider: GO:0008239 + +[Term] +id: GO:0004275 +name: obsolete enteropeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen." [EC:3.4.21.9] +comment: This term was made obsolete because it represents a gene product. +synonym: "enterokinase activity" RELATED [EC:3.4.21.9] +synonym: "enteropeptidase activity" EXACT [] +xref: EC:3.4.21.9 +xref: MetaCyc:3.4.21.9-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004276 +name: obsolete furin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors." [EC:3.4.21.75] +comment: This term was made obsolete because it represents a gene product. +synonym: "dibasic processing enzyme activity" EXACT [EC:3.4.21.75] +synonym: "furin activity" EXACT [] +synonym: "PACE" RELATED [EC:3.4.21.75] +synonym: "paired basic amino acid cleaving enzyme" RELATED [EC:3.4.21.75] +synonym: "paired basic amino acid converting enzyme" RELATED [EC:3.4.21.75] +synonym: "paired basic amino acid residue cleaving enzyme activity" EXACT [EC:3.4.21.75] +synonym: "prohormone convertase activity" NARROW [EC:3.4.21.75] +synonym: "serine proteinase PACE" RELATED [EC:3.4.21.75] +synonym: "SPC3" RELATED [EC:3.4.21.75] +xref: EC:3.4.21.75 +xref: MetaCyc:3.4.21.75-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004277 +name: obsolete granzyme A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates." [EC:3.4.21.78] +comment: This term was made obsolete because it represents a gene product. +synonym: "CTLA3" RELATED [EC:3.4.21.78] +synonym: "cytotoxic T lymphocyte serine protease" NARROW [EC:3.4.21.78] +synonym: "cytotoxic T-lymphocyte proteinase 1 activity" NARROW [EC:3.4.21.78] +synonym: "granzyme A activity" EXACT [] +synonym: "HuTPS" RELATED [EC:3.4.21.78] +synonym: "T-cell associated protease 1" RELATED [EC:3.4.21.78] +synonym: "T-cell derived serine proteinase" NARROW [EC:3.4.21.78] +synonym: "TSP-1" RELATED [EC:3.4.21.78] +xref: EC:3.4.21.78 +xref: MetaCyc:3.4.21.78-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004278 +name: obsolete granzyme B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa." [EC:3.4.21.79] +comment: This term was made obsolete because it represents a gene product. +synonym: "CCP1 proteinase" NARROW [EC:3.4.21.79] +synonym: "CCPII" RELATED [EC:3.4.21.79] +synonym: "CTLA1" RELATED [EC:3.4.21.79] +synonym: "cytotoxic cell proteinase-1" RELATED [EC:3.4.21.79] +synonym: "cytotoxic t-lymphocyte proteinase 2 activity" NARROW [EC:3.4.21.79] +synonym: "granzyme B activity" EXACT [] +synonym: "granzyme G" RELATED [EC:3.4.21.79] +synonym: "granzyme H" RELATED [EC:3.4.21.79] +xref: EC:3.4.21.79 +xref: MetaCyc:3.4.21.79-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004281 +name: obsolete pancreatic elastase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin." [EC:3.4.21.71] +comment: This term was made obsolete because it represents a gene product. +synonym: "pancreatic elastase 2" RELATED [EC:3.4.21.71] +synonym: "pancreatic elastase II activity" EXACT [] +xref: EC:3.4.21.71 +xref: MetaCyc:3.4.21.71-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004283 +name: obsolete plasmin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products." [EC:3.4.21.7] +comment: This term was made obsolete because it represents a gene product. +synonym: "actase activity" EXACT [EC:3.4.21.7] +synonym: "fibrinase activity" EXACT [EC:3.4.21.7] +synonym: "fibrinolysin activity" EXACT [EC:3.4.21.7] +synonym: "plasmin activity" EXACT [] +synonym: "serum tryptase activity" EXACT [EC:3.4.21.7] +synonym: "thrombolysin" RELATED [EC:3.4.21.7] +xref: EC:3.4.21.7 +xref: MetaCyc:3.4.21.7-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004284 +name: obsolete acrosin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa." [EC:3.4.21.10] +comment: This term was made obsolete because it represents a gene product. +synonym: "acrosin activity" EXACT [] +synonym: "acrosin amidase activity" EXACT [EC:3.4.21.10] +synonym: "acrosomal protease activity" EXACT [EC:3.4.21.10] +synonym: "acrosomal proteinase activity" EXACT [EC:3.4.21.10] +synonym: "acrozonase activity" EXACT [EC:3.4.21.10] +synonym: "alpha-acrosin" RELATED [EC:3.4.21.10] +synonym: "beta-acrosin" RELATED [EC:3.4.21.10] +synonym: "psi-acrosin" RELATED [EC:3.4.21.10] +xref: EC:3.4.21.10 +xref: MetaCyc:3.4.21.10-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004285 +name: obsolete proprotein convertase 1 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond." [EC:3.4.21.93] +comment: This term was made obsolete because it represents a gene product. +synonym: "NEC 1 activity" NARROW [EC:3.4.21.93] +synonym: "neuroendocrine convertase 1 activity" NARROW [EC:3.4.21.93] +synonym: "PC1 activity" NARROW [EC:3.4.21.93] +synonym: "prohormone convertase 3" RELATED [EC:3.4.21.93] +synonym: "prohormone convertase I activity" NARROW [EC:3.4.21.93] +synonym: "proprotein convertase 1 activity" EXACT [] +xref: EC:3.4.21.93 +xref: MetaCyc:3.4.21.93-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004286 +name: obsolete proprotein convertase 2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond." [EC:3.4.21.94] +comment: This term was made obsolete because it represents a gene product. +synonym: "NEC 2 activity" NARROW [EC:3.4.21.94] +synonym: "neuroendocrine convertase 2 activity" NARROW [EC:3.4.21.94] +synonym: "PC2 activity" NARROW [EC:3.4.21.94] +synonym: "prohormone convertase II activity" NARROW [EC:3.4.21.94] +synonym: "proprotein convertase 2 activity" EXACT [] +xref: EC:3.4.21.94 +xref: MetaCyc:3.4.21.94-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004287 +name: obsolete prolyl oligopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides." [EC:3.4.21.26] +comment: This term was made obsolete because it represents a gene product. +synonym: "endoprolylpeptidase activity" EXACT [EC:3.4.21.26] +synonym: "post-proline cleaving enzyme activity" EXACT [EC:3.4.21.26] +synonym: "post-proline endopeptidase activity" EXACT [EC:3.4.21.26] +synonym: "proline endopeptidase activity" EXACT [EC:3.4.21.26] +synonym: "proline-specific endopeptidase activity" EXACT [EC:3.4.21.26] +synonym: "prolyl endopeptidase activity" EXACT [EC:3.4.21.26] +synonym: "prolyl oligopeptidase activity" EXACT [] +xref: EC:3.4.21.26 +xref: MetaCyc:3.4.21.26-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004289 +name: obsolete subtilase activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "subtilase activity" EXACT [] +xref: EC:3.4.21 +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004290 +name: obsolete kexin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors." [EC:3.4.21.61] +comment: This term was made obsolete because it represents a gene product. +synonym: "andrenorphin-Gly-generating enzyme" RELATED [EC:3.4.21.61] +synonym: "endoproteinase Kex2p" RELATED [EC:3.4.21.61] +synonym: "gene KEX2 dibasic proteinase" NARROW [EC:3.4.21.61] +synonym: "Kex 2p proteinase" NARROW [EC:3.4.21.61] +synonym: "Kex2 endopeptidase" NARROW [EC:3.4.21.61] +synonym: "Kex2 endoprotease" NARROW [EC:3.4.21.61] +synonym: "Kex2 endoproteinase" NARROW [EC:3.4.21.61] +synonym: "Kex2 protease" NARROW [EC:3.4.21.61] +synonym: "Kex2 proteinase" NARROW [EC:3.4.21.61] +synonym: "Kex2-like endoproteinase" NARROW [EC:3.4.21.61] +synonym: "Kex2-like precursor protein processing endoprotease" NARROW [EC:3.4.21.61] +synonym: "kexin activity" EXACT [] +synonym: "paired-basic endopeptidase activity" EXACT [EC:3.4.21.61] +synonym: "prohormone-processing endoprotease activity" RELATED [EC:3.4.21.61] +synonym: "prohormone-processing KEX2 proteinase" NARROW [EC:3.4.21.61] +synonym: "prohormone-processing proteinase activity" EXACT [EC:3.4.21.61] +synonym: "protease KEX2" RELATED [EC:3.4.21.61] +synonym: "proteinase Kex2p" RELATED [EC:3.4.21.61] +synonym: "proteinase yscF activity" NARROW [EC:3.4.21.61] +synonym: "yeast cysteine proteinase F" RELATED [EC:3.4.21.61] +synonym: "yeast KEX2 protease activity" NARROW [EC:3.4.21.61] +xref: EC:3.4.21.61 +xref: MetaCyc:3.4.21.61-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004291 +name: obsolete subtilisin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides." [EC:3.4.21.62] +comment: This term was made obsolete because it represents a gene product. +synonym: "alcalase 0.6L" RELATED [EC:3.4.21.62] +synonym: "alcalase 2.5L" RELATED [EC:3.4.21.62] +synonym: "alcalase activity" EXACT [EC:3.4.21.62] +synonym: "ALK-enzyme" RELATED [EC:3.4.21.62] +synonym: "bacillopeptidase A" RELATED [EC:3.4.21.62] +synonym: "bacillopeptidase B" RELATED [EC:3.4.21.62] +synonym: "bacillus subtilis alkaline proteinase activity" EXACT [EC:3.4.21.62] +synonym: "bacillus subtilis alkaline proteinase bioprase activity" EXACT [EC:3.4.21.62] +synonym: "bioprase AL 15" RELATED [EC:3.4.21.62] +synonym: "bioprase APL 30" RELATED [EC:3.4.21.62] +synonym: "colistinase activity" EXACT [EC:3.4.21.62] +synonym: "esperase activity" EXACT [EC:3.4.21.62] +synonym: "genenase I" RELATED [EC:3.4.21.62] +synonym: "kazusase activity" EXACT [EC:3.4.21.62] +synonym: "maxatase activity" EXACT [EC:3.4.21.62] +synonym: "opticlean" RELATED [EC:3.4.21.62] +synonym: "orientase 10B" RELATED [EC:3.4.21.62] +synonym: "protease S" RELATED [EC:3.4.21.62] +synonym: "protease VIII" RELATED [EC:3.4.21.62] +synonym: "protease XXVII" RELATED [EC:3.4.21.62] +synonym: "protin A 3L" RELATED [EC:3.4.21.62] +synonym: "savinase 16.0L" RELATED [EC:3.4.21.62] +synonym: "savinase 32.0 L EX" RELATED [EC:3.4.21.62] +synonym: "savinase 4.0T" RELATED [EC:3.4.21.62] +synonym: "savinase 8.0L" RELATED [EC:3.4.21.62] +synonym: "savinase activity" EXACT [EC:3.4.21.62] +synonym: "SP 266" RELATED [EC:3.4.21.62] +synonym: "subtilisin activity" EXACT [] +synonym: "subtilisin BL" RELATED [EC:3.4.21.62] +synonym: "subtilisin DY" RELATED [EC:3.4.21.62] +synonym: "subtilisin E" RELATED [EC:3.4.21.62] +synonym: "subtilisin GX" RELATED [EC:3.4.21.62] +synonym: "subtilisin J" RELATED [EC:3.4.21.62] +synonym: "subtilisin S41" RELATED [EC:3.4.21.62] +synonym: "subtilisin sendai" RELATED [EC:3.4.21.62] +synonym: "subtilopeptidase activity" EXACT [EC:3.4.21.62] +synonym: "superase activity" EXACT [EC:3.4.21.62] +synonym: "thermoase" BROAD [EC:3.4.21.62] +synonym: "thermoase PC 10" RELATED [EC:3.4.21.62] +xref: EC:3.4.21.62 +xref: MetaCyc:3.4.21.62-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004293 +name: obsolete tissue kallikrein activity +namespace: molecular_function +alt_id: GO:0004279 +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds." [EC:3.4.21.35] +comment: This term was made obsolete because it represents a gene product. +synonym: "bradykininogenase" BROAD [EC:3.4.21.35] +synonym: "callicrein" RELATED [EC:3.4.21.35] +synonym: "depot-padutin" RELATED [EC:3.4.21.35] +synonym: "dilminal D" RELATED [EC:3.4.21.35] +synonym: "glandular kallikrein activity" RELATED [EC:3.4.21.35] +synonym: "glumorin" RELATED [EC:3.4.21.35] +synonym: "kallidinogenase" BROAD [EC:3.4.21.35] +synonym: "kallikrein" RELATED [EC:3.4.21.35] +synonym: "kidney kallikrein" RELATED [EC:3.4.21.35] +synonym: "kininogenase" BROAD [EC:3.4.21.35] +synonym: "kininogenin activity" RELATED [EC:3.4.21.35] +synonym: "onokrein P" RELATED [EC:3.4.21.35] +synonym: "padreatin" RELATED [EC:3.4.21.35] +synonym: "padutin" RELATED [EC:3.4.21.35] +synonym: "pancreatic kallikrein" RELATED [EC:3.4.21.35] +synonym: "salivary kallikrein" RELATED [EC:3.4.21.35] +synonym: "submandibular kallikrein" RELATED [EC:3.4.21.35] +synonym: "submaxillary kallikrein" RELATED [EC:3.4.21.35] +synonym: "tissue kallikrein activity" EXACT [] +synonym: "urinary kallikrein" RELATED [EC:3.4.21.35] +synonym: "urokallikrein" RELATED [EC:3.4.21.35] +xref: EC:3.4.21.35 +xref: MetaCyc:3.4.21.35-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004294 +name: obsolete tripeptidyl-peptidase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH." [EC:3.4.14.10] +comment: This term was made obsolete because it represents a gene product. +synonym: "TPP" RELATED [EC:3.4.14.10] +synonym: "tripeptidyl aminopeptidase activity" BROAD [EC:3.4.14.10] +synonym: "tripeptidyl aminopeptidase II" RELATED [EC:3.4.14.10] +synonym: "tripeptidyl peptidase activity" BROAD [EC:3.4.14.10] +synonym: "tripeptidyl peptidase II" RELATED [EC:3.4.14.10] +synonym: "tripeptidyl-peptidase II activity" EXACT [] +xref: EC:3.4.14.10 +xref: MetaCyc:3.4.14.10-RXN +is_obsolete: true +replaced_by: GO:0008240 + +[Term] +id: GO:0004295 +name: obsolete trypsin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa." [EC:3.4.21.4] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-trypsin activity" NARROW [EC:3.4.21.4] +synonym: "beta-trypsin activity" NARROW [EC:3.4.21.4] +synonym: "cocoonase activity" EXACT [EC:3.4.21.4] +synonym: "parenzyme" RELATED [EC:3.4.21.4] +synonym: "parenzymol" RELATED [EC:3.4.21.4] +synonym: "pseudotrypsin" RELATED [EC:3.4.21.4] +synonym: "sperm receptor hydrolase activity" EXACT [EC:3.4.21.4] +synonym: "tripcellim" RELATED [EC:3.4.21.4] +synonym: "trypsin activity" EXACT [] +synonym: "tryptar" RELATED [EC:3.4.21.4] +synonym: "trypure" RELATED [EC:3.4.21.4] +xref: EC:3.4.21.4 +xref: MetaCyc:3.4.21.4-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0004298 +name: threonine-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] +synonym: "26S protease" RELATED [EC:3.4.25] +synonym: "alkaline protease" RELATED [EC:3.4.25] +synonym: "ingensin" RELATED [EC:3.4.25] +synonym: "large multicatalytic protease" NARROW [EC:3.4.25] +synonym: "lens neutral proteinase" NARROW [EC:3.4.25] +synonym: "MCP" RELATED [EC:3.4.25] +synonym: "multicatalytic endopeptidase complex" RELATED [EC:3.4.25] +synonym: "multicatalytic proteinase" NARROW [EC:3.4.25] +synonym: "multicatalytic proteinase (complex)" NARROW [EC:3.4.25] +synonym: "prosome" RELATED [EC:3.4.25] +synonym: "proteasome endopeptidase complex" NARROW [EC:3.4.25] +synonym: "threonine endopeptidase activity" EXACT [] +synonym: "tricorn protease" NARROW [EC:3.4.25] +synonym: "tricorn proteinase" NARROW [EC:3.4.25] +xref: EC:3.4.25 +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0070003 ! threonine-type peptidase activity + +[Term] +id: GO:0004299 +name: obsolete proteasome endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity." [EC:3.4.25.1] +comment: This term was made obsolete because it mentions a component term in the text string. +synonym: "multicatalytic endopeptidase" RELATED [] +synonym: "proteasome" RELATED [] +synonym: "proteasome endopeptidase activity" EXACT [] +synonym: "proteasome endopeptidase complex" RELATED [] +is_obsolete: true +consider: GO:0004175 +consider: GO:0008233 + +[Term] +id: GO:0004300 +name: enoyl-CoA hydratase activity +namespace: molecular_function +alt_id: GO:0016510 +def: "Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O." [EC:4.2.1.17] +synonym: "(3S)-3-hydroxyacyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.17] +synonym: "2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17] +synonym: "2-octenoyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17] +synonym: "acyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17] +synonym: "beta-hydroxyacid dehydrase activity" EXACT [EC:4.2.1.17] +synonym: "beta-hydroxyacyl-CoA dehydrase activity" EXACT [EC:4.2.1.17] +synonym: "crotonyl hydrase activity" EXACT [EC:4.2.1.17] +synonym: "D-3-hydroxyacyl-CoA dehydratase" BROAD [EC:4.2.1.17] +synonym: "ECH" RELATED [EC:4.2.1.17] +synonym: "enol-CoA hydratase activity" EXACT [EC:4.2.1.17] +synonym: "enoyl coenzyme A hydrase (D)" BROAD [EC:4.2.1.17] +synonym: "enoyl coenzyme A hydrase (L)" EXACT [EC:4.2.1.17] +synonym: "enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17] +synonym: "enoyl hydrase activity" EXACT [EC:4.2.1.17] +synonym: "hydratase, enoyl coenzyme A" EXACT [EC:4.2.1.17] +synonym: "short chain enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17] +synonym: "short-chain enoyl-CoA hydratase activity" EXACT [] +synonym: "trans-2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17] +synonym: "unsaturated acyl-CoA hydratase activity" EXACT [EC:4.2.1.17] +xref: EC:4.2.1.17 +xref: MetaCyc:ENOYL-COA-HYDRAT-RXN +xref: Reactome:R-HSA-70830 "tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA" +xref: Reactome:R-HSA-70870 "methacrylyl-CoA + H2O <=> beta-hydroxyisobutyryl-CoA" +xref: Reactome:R-HSA-77256 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA" +xref: Reactome:R-HSA-77277 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA" +xref: Reactome:R-HSA-77301 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA" +xref: Reactome:R-HSA-77314 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA" +xref: Reactome:R-HSA-77325 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA" +xref: Reactome:R-HSA-77333 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA" +xref: Reactome:R-HSA-77344 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA" +xref: RHEA:16105 +xref: UM-BBD_enzymeID:e0014 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004301 +name: epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: an epoxide + H2O = a glycol." [EC:3.3.2.10] +subset: goslim_chembl +synonym: "arene-oxide hydratase activity" BROAD [EC:3.3.2.10] +synonym: "aryl epoxide hydrase activity" BROAD [EC:3.3.2.10] +synonym: "cytosolic epoxide hydrolase activity" EXACT [EC:3.3.2.10] +synonym: "epoxide hydrase activity" BROAD [EC:3.3.2.10] +synonym: "epoxide hydratase activity" BROAD [EC:3.3.2.10] +synonym: "sEH" RELATED [EC:3.3.2.10] +synonym: "soluble epoxide hydrolase activity" NARROW [EC:3.3.2.10] +synonym: "trans-stilbene oxide hydrolase activity" EXACT [EC:3.3.2.10] +xref: EC:3.3.2.10 +xref: MetaCyc:3.3.2.10-RXN +xref: Reactome:R-HSA-2161961 "EET(1) is hydrolysed to DHET(1) by EPHX2" +xref: Reactome:R-HSA-9018862 "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1" +xref: Reactome:R-HSA-9018877 "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1" +xref: Reactome:R-HSA-9020252 "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2" +xref: Reactome:R-HSA-9020253 "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4" +xref: Reactome:R-HSA-9020257 "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1" +xref: Reactome:R-HSA-9020258 "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2" +xref: Reactome:R-HSA-9020270 "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4" +xref: Reactome:R-HSA-9024890 "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1" +xref: Reactome:R-HSA-9024973 "Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1" +xref: Reactome:R-HSA-9024993 "EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2" +xref: Reactome:R-HSA-9025998 "Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA" +xref: Reactome:R-HSA-9026000 "Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA" +xref: Reactome:R-HSA-9026008 "Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA" +xref: UM-BBD_enzymeID:e0397 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0004303 +name: estradiol 17-beta-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+." [EC:1.1.1.62] +synonym: "17-beta-estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "17-beta-HSD activity" BROAD [EC:1.1.1.62] +synonym: "17-beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.62] +synonym: "17beta,20alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "17beta-estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "17beta-HSD" RELATED [EC:1.1.1.62] +synonym: "17beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.62] +synonym: "estradiol 17beta-dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] +synonym: "estradiol-17beta:NAD(P)+ 17-oxidoreductase activity" EXACT [EC:1.1.1.62] +synonym: "estrogen 17-oxidoreductase activity" EXACT [EC:1.1.1.62] +xref: EC:1.1.1.62 +xref: MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-5693390 "HSD17B11 dehydrogenates EST17b to E1" +xref: Reactome:R-HSA-5696822 "AKR1B15 reduces EST17b to E1" +xref: Reactome:R-HSA-6810594 "HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1)" +xref: Reactome:R-HSA-804969 "HSD17B1 hydrogenates E1 to EST17b" +xref: Reactome:R-HSA-8862137 "HSD17B2 oxidises estradiol (E2) to estrone (E1)" +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004304 +name: estrone sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate." [EC:2.8.2.4] +synonym: "3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity" EXACT [EC:2.8.2.4] +synonym: "3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity" EXACT [EC:2.8.2.4] +synonym: "3'-phosphoadenylylsulfate:oestrone sulfotransferase activity" EXACT [EC:2.8.2.4] +synonym: "estrogen sulfotransferase" BROAD [EC:2.8.2.4] +synonym: "estrogen sulphotransferase activity" EXACT [EC:2.8.2.4] +synonym: "estrone sulphotransferase activity" EXACT [] +synonym: "oestrogen sulphotransferase activity" EXACT [EC:2.8.2.4] +xref: EC:2.8.2.4 +xref: MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-176664 "estrone + PAPS => estrone 3-sulfate + PAP" +xref: RHEA:15973 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0004305 +name: ethanolamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine." [EC:2.7.1.82, RHEA:13069] +synonym: "ATP:ethanolamine O-phosphotransferase activity" EXACT [EC:2.7.1.82] +synonym: "ethanolamine kinase (phosphorylating)" EXACT [EC:2.7.1.82] +synonym: "ethanolamine phosphokinase activity" EXACT [EC:2.7.1.82] +xref: EC:2.7.1.82 +xref: KEGG_REACTION:R01468 +xref: MetaCyc:ETHANOLAMINE-KINASE-RXN +xref: Reactome:R-HSA-1483222 "ETA is phosphorylated to PETA by CHK/ETNK" +xref: RHEA:13069 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004306 +name: ethanolamine-phosphate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine." [EC:2.7.7.14] +synonym: "CTP-phosphoethanolamine cytidylyltransferase activity" EXACT [EC:2.7.7.14] +synonym: "CTP:ethanolamine-phosphate cytidylyltransferase activity" EXACT [] +synonym: "CTP:phosphoethanolamine cytidylyltransferase activity" EXACT [EC:2.7.7.14] +synonym: "ET" RELATED [EC:2.7.7.14] +synonym: "ethanolamine phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.14] +synonym: "phosphoethanolamine cytidylyltransferase activity" EXACT [] +synonym: "phosphorylethanolamine transferase activity" BROAD [EC:2.7.7.14] +xref: EC:2.7.7.14 +xref: MetaCyc:2.7.7.14-RXN +xref: Reactome:R-HSA-1483190 "PETA and CTP are condensed to CDP-ETA by PCY2" +xref: RHEA:24592 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0004307 +name: ethanolaminephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine." [EC:2.7.8.1, RHEA:32943] +synonym: "CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.1] +synonym: "CDPethanolamine diglyceride phosphotransferase activity" EXACT [EC:2.7.8.1] +synonym: "diacylglycerol ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.1] +synonym: "EPT" RELATED [EC:2.7.8.1] +synonym: "phosphorylethanolamine-glyceride transferase activity" EXACT [EC:2.7.8.1] +xref: EC:2.7.8.1 +xref: MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN +xref: Reactome:R-HSA-1482962 "CDP-ETA and DAG are converted to PE by CEPT1/EPT1" +xref: RHEA:32943 +is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity + +[Term] +id: GO:0004308 +name: exo-alpha-sialidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates." [EC:3.2.1.18] +synonym: "acetylneuraminidase activity" EXACT [EC:3.2.1.18] +synonym: "acetylneuraminyl hydrolase activity" EXACT [EC:3.2.1.18] +synonym: "alpha-neuraminidase activity" EXACT [EC:3.2.1.18] +synonym: "N-acylneuraminate glycohydrolase activity" EXACT [EC:3.2.1.18] +synonym: "neuraminidase activity" EXACT [EC:3.2.1.18] +synonym: "sialidase activity" EXACT [EC:3.2.1.18] +xref: EC:3.2.1.18 +xref: MetaCyc:3.2.1.18-RXN +xref: Reactome:R-HSA-1605723 "Neu5Ac is cleaved from GM3 by NEU2 to form a globoside (cytosol)" +xref: Reactome:R-HSA-1605724 "Neu5Ac is cleaved from GM3 by NEU1 and 4 to form a globoside (lysosomal lumen)" +xref: Reactome:R-HSA-1605768 "Neu5Ac is cleaved from GM3 by NEU3 to form globoside (plasma membrane)" +xref: Reactome:R-HSA-168870 "Neuraminidase enzymatic release from sialic acid" +xref: Reactome:R-HSA-4084994 "NEU3 hydrolyzes Neu5Ac from glycoconjugates" +xref: Reactome:R-HSA-4084999 "NEU1 hydrolyses Neu5Ac from glycoconjugates" +xref: Reactome:R-HSA-4085029 "NEU2 hydrolyzes Neu5Ac from glycoconjugates" +xref: Reactome:R-HSA-4341669 "Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates" +xref: Reactome:R-HSA-9638120 "NEU4 hydrolyses Neu5Ac from glycoconjugates" +is_a: GO:0016997 ! alpha-sialidase activity + +[Term] +id: GO:0004309 +name: exopolyphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate." [EC:3.6.1.11] +synonym: "acid phosphoanhydride phosphohydrolase activity" EXACT [EC:3.6.1.11] +synonym: "exopolypase activity" EXACT [EC:3.6.1.11] +synonym: "Gra-Pase activity" EXACT [EC:3.6.1.11] +synonym: "metaphosphatase activity" BROAD [EC:3.6.1.11] +synonym: "polyphosphate phosphohydrolase activity" EXACT [EC:3.6.1.11] +xref: EC:3.6.1.11 +xref: MetaCyc:EXOPOLYPHOSPHATASE-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0004310 +name: farnesyl-diphosphate farnesyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate." [EC:2.5.1.21] +comment: Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'. +synonym: "farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity" EXACT [EC:2.5.1.21] +synonym: "presqualene synthase activity" EXACT [EC:2.5.1.21] +synonym: "presqualene-diphosphate synthase activity" EXACT [EC:2.5.1.21] +xref: EC:2.5.1.21 +xref: MetaCyc:2.5.1.21-RXN +xref: Reactome:R-HSA-191402 "Reduction of presqualene diphosphate to form squalene" +xref: Reactome:R-HSA-191405 "Two FPP molecules dimerize to form presqualene diphosphate" +is_a: GO:0004311 ! farnesyltranstransferase activity + +[Term] +id: GO:0004311 +name: farnesyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate." [EC:2.5.1.29, RHEA:17653] +comment: The catalyzed reaction forms (free) geranylgeranyl diphosphate. There is no relationship between this activity and protein farnesyltransferase activity, GO:0004660, where the catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. +synonym: "farnesyltransferase activity" BROAD [EC:2.5.1.29] +synonym: "geranylgeranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.29] +synonym: "geranylgeranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.29] +synonym: "geranylgeranyl-diphosphate synthase activity" EXACT [EC:2.5.1.29] +synonym: "geranylgeranyl-PP synthetase activity" EXACT [EC:2.5.1.29] +synonym: "trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" EXACT [EC:2.5.1.29] +xref: EC:2.5.1.29 +xref: KEGG_REACTION:R02061 +xref: MetaCyc:FARNESYLTRANSTRANSFERASE-RXN +xref: RHEA:17653 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0004312 +name: fatty acid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+." [EC:2.3.1.85] +synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)" EXACT [EC:2.3.1.85] +synonym: "fatty-acid synthase activity" EXACT [] +xref: EC:2.3.1.85 +xref: MetaCyc:FATTY-ACID-SYNTHASE-RXN +xref: Reactome:R-HSA-75872 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0004313 +name: [acyl-carrier-protein] S-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]." [EC:2.3.1.38] +synonym: "[acyl-carrier protein] S-acetyltransferase activity" EXACT [] +synonym: "ACAT activity" BROAD [EC:2.3.1.38] +synonym: "acetyl coenzyme A-acyl-carrier-protein transacylase activity" EXACT [EC:2.3.1.38] +synonym: "acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity" EXACT [EC:2.3.1.38] +synonym: "ACP acetyltransferase activity" EXACT [EC:2.3.1.38] +synonym: "ACP S-acetyltransferase activity" EXACT [] +synonym: "ACPacetyltransferase activity" EXACT [EC:2.3.1.38] +synonym: "acyl-carrier-protein acetyltransferase activity" EXACT [EC:2.3.1.38] +synonym: "acyl-carrier-protein S-acetyltransferase activity" EXACT [EC:2.3.1.38] +synonym: "acyl-carrier-proteinacetyltransferase activity" EXACT [EC:2.3.1.38] +xref: EC:2.3.1.38 +xref: MetaCyc:ACP-S-ACETYLTRANSFER-RXN +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016418 ! S-acetyltransferase activity + +[Term] +id: GO:0004314 +name: [acyl-carrier-protein] S-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]." [EC:2.3.1.39] +synonym: "[acyl-carrier protein] S-malonyltransferase activity" EXACT [] +synonym: "ACP S-malonyltransferase activity" EXACT [] +synonym: "acyl carrier protein malonyltransferase activity" EXACT [EC:2.3.1.39] +synonym: "acyl carrier proteinmalonyltransferase activity" EXACT [EC:2.3.1.39] +synonym: "acyl-carrier-protein S-malonyltransferase activity" EXACT [EC:2.3.1.39] +synonym: "FabD" RELATED [EC:2.3.1.39] +synonym: "malonyl coenzyme A-acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] +synonym: "malonyl transacylase activity" BROAD [EC:2.3.1.39] +synonym: "malonyl transferase activity" BROAD [EC:2.3.1.39] +synonym: "malonyl-CoA-acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] +synonym: "malonyl-CoA:ACP transacylase activity" EXACT [EC:2.3.1.39] +synonym: "malonyl-CoA:AcpM transacylase activity" EXACT [EC:2.3.1.39] +synonym: "malonyl-CoA:acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] +synonym: "malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity" EXACT [EC:2.3.1.39] +synonym: "MAT" RELATED [EC:2.3.1.39] +synonym: "MCAT activity" EXACT [EC:2.3.1.39] +xref: EC:2.3.1.39 +xref: MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN +xref: Reactome:R-HSA-8933547 "MCAT transfers Mal from Mal-CoA to NDUFAB1" +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016419 ! S-malonyltransferase activity + +[Term] +id: GO:0004315 +name: 3-oxoacyl-[acyl-carrier-protein] synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]." [EC:2.3.1.41] +synonym: "3-ketoacyl-acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] +synonym: "3-oxoacyl-[acyl-carrier protein] synthase activity" EXACT [] +synonym: "3-oxoacyl-ACP synthase activity" EXACT [] +synonym: "3-oxoacyl-acyl-carrier-protein synthase activity" EXACT [EC:2.3.1.41] +synonym: "3-oxoacyl:ACP synthase I" RELATED [EC:2.3.1.41] +synonym: "acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)" EXACT [EC:2.3.1.41] +synonym: "acyl-malonyl acyl carrier protein-condensing enzyme activity" EXACT [EC:2.3.1.41] +synonym: "acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl synthetase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-[acyl carrier protein] synthase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-ACP synthase I activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-ACP synthetase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-acyl carrier protein synthetase activity" EXACT [EC:2.3.1.41] +synonym: "beta-ketoacyl-acyl-carrier-protein synthase I" RELATED [EC:2.3.1.41] +synonym: "beta-ketoacylsynthase activity" EXACT [EC:2.3.1.41] +synonym: "condensing enzyme activity" BROAD [EC:2.3.1.41] +synonym: "FabB" RELATED [EC:2.3.1.41] +synonym: "FabF1" RELATED [EC:2.3.1.41] +synonym: "fatty acid condensing enzyme activity" BROAD [EC:2.3.1.41] +synonym: "KAS I activity" NARROW [EC:2.3.1.41] +synonym: "KASI" RELATED [EC:2.3.1.41] +synonym: "ketoacyl-ACP synthase activity" EXACT [] +xref: EC:2.3.1.41 +xref: MetaCyc:3-OXOACYL-ACP-SYNTH-RXN +is_a: GO:0004312 ! fatty acid synthase activity + +[Term] +id: GO:0004316 +name: 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+." [EC:1.1.1.100] +synonym: "(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.100] +synonym: "3-ketoacyl acyl carrier protein reductase activity" EXACT [EC:1.1.1.100] +synonym: "3-oxoacyl-[acyl-carrier protein] reductase activity" EXACT [] +synonym: "3-oxoacyl-ACP reductase activity" EXACT [] +synonym: "3-oxoacyl-ACPreductase activity" EXACT [EC:1.1.1.100] +synonym: "3-oxoacyl-acyl-carrier-protein reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl acyl carrier protein (ACP) reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl thioester reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl-ACP reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl-acyl carrier protein reductase activity" EXACT [EC:1.1.1.100] +synonym: "beta-ketoacyl-acyl-carrier protein(ACP) reductase activity" EXACT [EC:1.1.1.100] +synonym: "NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity" EXACT [EC:1.1.1.100] +xref: EC:1.1.1.100 +xref: MetaCyc:3-OXOACYL-ACP-REDUCT-RXN +xref: Reactome:R-HSA-8862152 "2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP" +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004317 +name: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O." [PMID:8088535, RHEA:41908] +synonym: "(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.59] +synonym: "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)" EXACT [] +synonym: "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity" EXACT [] +synonym: "3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity" EXACT [] +synonym: "3-hydroxypalmitoyl-ACP dehydratase activity" EXACT [] +synonym: "3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity" EXACT [] +synonym: "beta-hydroxypalmitoyl thioester dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxypalmityl-ACP dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.59] +xref: EC:4.2.1.59 +xref: KEGG_REACTION:R04462 +xref: MetaCyc:4.2.1.61-RXN +xref: RHEA:41908 +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0019171 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity + +[Term] +id: GO:0004318 +name: enoyl-[acyl-carrier-protein] reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+." [EC:1.3.1.9] +synonym: "acyl-acyl-carrier-protein:NAD+ oxidoreductase" EXACT [EC:1.3.1.9] +synonym: "enoyl-[acyl-carrier protein] reductase (NADH) activity" EXACT [EC:1.3.1.9] +synonym: "enoyl-ACP reductase (NADH) activity" EXACT [EC:1.3.1.9] +synonym: "enoyl-acyl-carrier-protein reductase (NADH)" EXACT [EC:1.3.1.9] +synonym: "NADH-enoyl acyl carrier protein reductase activity" EXACT [EC:1.3.1.9] +synonym: "NADH-specific enoyl-ACP reductase activity" EXACT [EC:1.3.1.9] +xref: EC:1.3.1.9 +xref: MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004319 +name: enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+." [EC:1.3.1.10] +synonym: "acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)" EXACT [EC:1.3.1.10] +synonym: "enoyl acyl-carrier-protein reductase activity" EXACT [EC:1.3.1.10] +synonym: "enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity" EXACT [] +synonym: "enoyl-ACP reductase (NADPH, B-specific) activity" EXACT [] +synonym: "enoyl-acyl-carrier-protein reductase (NADPH, B-specific)" EXACT [EC:1.3.1.10] +synonym: "enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)" EXACT [EC:1.3.1.10] +synonym: "NADPH 2-enoyl Co A reductase activity" EXACT [EC:1.3.1.10] +synonym: "reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.10] +xref: EC:1.3.1.10 +xref: MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004320 +name: oleoyl-[acyl-carrier-protein] hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate." [EC:3.1.2.14] +synonym: "oleoyl-[acyl-carrier protein] hydrolase activity" EXACT [] +synonym: "oleoyl-ACP hydrolase activity" EXACT [] +synonym: "oleoyl-ACP thioesterase activity" EXACT [EC:3.1.2.14] +synonym: "oleoyl-acyl carrier protein thioesterase activity" EXACT [EC:3.1.2.14] +synonym: "oleoyl-acyl-carrier-protein hydrolase" BROAD [EC:3.1.2.14] +xref: EC:3.1.2.14 +xref: MetaCyc:3.1.2.14-RXN +xref: MetaCyc:PWY-5142 +is_a: GO:0016297 ! acyl-[acyl-carrier-protein] hydrolase activity + +[Term] +id: GO:0004321 +name: fatty-acyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+." [EC:2.3.1.86] +synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing)" EXACT [EC:2.3.1.86] +synonym: "fatty acyl CoA synthase activity" EXACT [] +synonym: "yeast fatty acid synthase activity" NARROW [EC:2.3.1.86] +xref: EC:2.3.1.86 +xref: MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN +is_a: GO:0016408 ! C-acyltransferase activity + +[Term] +id: GO:0004322 +name: ferroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O." [EC:1.16.3.1] +synonym: "caeruloplasmin" RELATED [EC:1.16.3.1] +synonym: "ceruloplasmin activity" NARROW [EC:1.16.3.1] +synonym: "Fe(II):oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] +synonym: "ferro:O2 oxidoreductase activity" EXACT [EC:1.16.3.1] +synonym: "ferroxidase I" RELATED [EC:1.16.3.1] +synonym: "ferroxidase, iron II:oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] +synonym: "iron(II): oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] +synonym: "multicopper ferroxidase iron transport mediator activity" NARROW [] +xref: EC:1.16.3.1 +xref: MetaCyc:RXN0-1483 +xref: Reactome:R-HSA-1562603 "BfrB stores iron" +xref: Reactome:R-HSA-1562604 "BfrA stores iron" +xref: Reactome:R-HSA-1562626 "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)" +xref: Reactome:R-HSA-5621402 "Defective CP does not oxidise Fe2+ to Fe3+" +xref: Reactome:R-HSA-5691107 "FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH)" +xref: Reactome:R-HSA-917891 "SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+" +xref: Reactome:R-HSA-917933 "SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+" +xref: RHEA:11148 +is_a: GO:0016724 ! oxidoreductase activity, oxidizing metal ions, oxygen as acceptor + +[Term] +id: GO:0004323 +name: obsolete multicopper ferroxidase iron transport mediator activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O." [EC:1.16.3.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "multicopper ferroxidase iron transport mediator activity" EXACT [] +is_obsolete: true +consider: GO:0004322 +consider: GO:0005381 + +[Term] +id: GO:0004324 +name: ferredoxin-NADP+ reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+." [EC:1.18.1.2, GOC:kd] +comment: Note that this term specifically refers to the reaction proceeding in the direction shown; it should therefore be used to annotate gene products that catalyze the oxidation of reduced ferredoxin or adrenodoxin; also consider annotating to the molecular function term 'NADPH-adrenodoxin reductase activity ; GO:0015039'. +synonym: "ferredoxin-NADP oxidoreductase activity" EXACT [EC:1.18.1.2] +synonym: "ferredoxin-NADP reductase activity" EXACT [] +synonym: "ferredoxin-NADP-oxidoreductase activity" EXACT [EC:1.18.1.2] +synonym: "ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity" EXACT [EC:1.18.1.2] +synonym: "ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity" EXACT [EC:1.18.1.2] +synonym: "ferredoxin-TPN reductase activity" EXACT [EC:1.18.1.2] +synonym: "ferredoxin:NADP+ oxidoreductase activity" EXACT [EC:1.18.1.2] +synonym: "NADP:ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.2] +synonym: "NADPH:ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.2] +synonym: "reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity" EXACT [EC:1.18.1.2] +synonym: "TPNH-ferredoxin reductase activity" EXACT [EC:1.18.1.2] +xref: EC:1.18.1.2 +xref: MetaCyc:1.18.1.2-RXN +is_a: GO:0008937 ! ferredoxin-NAD(P) reductase activity + +[Term] +id: GO:0004325 +name: ferrochelatase activity +namespace: molecular_function +def: "Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX." [EC:4.99.1.1, RHEA:22584] +synonym: "ferro-protoporphyrin chelatase activity" EXACT [EC:4.99.1.1] +synonym: "heme synthase activity" EXACT [EC:4.99.1.1] +synonym: "heme synthetase activity" EXACT [EC:4.99.1.1] +synonym: "iron chelatase activity" EXACT [EC:4.99.1.1] +synonym: "protoheme ferro-lyase (protoporphyrin-forming)" EXACT [EC:4.99.1.1] +synonym: "protoheme ferro-lyase activity" EXACT [EC:4.99.1.1] +synonym: "protoheme ferrolyase activity" EXACT [EC:4.99.1.1] +xref: EC:4.99.1.1 +xref: KEGG_REACTION:R00310 +xref: MetaCyc:PROTOHEMEFERROCHELAT-RXN +xref: Reactome:R-HSA-189465 "FECH binds Fe2+ to PRIN9 to form heme" +xref: RHEA:22584 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0004326 +name: tetrahydrofolylpolyglutamate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1)." [EC:6.3.2.17] +synonym: "folate polyglutamate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "folylpoly(gamma-glutamate) synthase activity" EXACT [EC:6.3.2.17] +synonym: "folylpoly-gamma-glutamate synthase activity" EXACT [EC:6.3.2.17] +synonym: "folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "folylpolyglutamate synthase activity" EXACT [] +synonym: "folylpolyglutamate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "folylpolyglutamyl synthetase activity" EXACT [EC:6.3.2.17] +synonym: "formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "FPGS activity" EXACT [EC:6.3.2.17] +synonym: "N(10)-formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "N10-formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] +synonym: "tetrahydrofolate synthase activity" EXACT [EC:6.3.2.17] +synonym: "tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity" EXACT [EC:6.3.2.17] +synonym: "tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.17] +synonym: "tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.17] +xref: EC:6.3.2.17 +xref: MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN +xref: Reactome:R-HSA-197958 "Conversion of cytosolic THF to THF-polyglutamate" +xref: Reactome:R-HSA-200681 "Conversion of cytosolic 5-methyltetrahydrofolate (5-methylTHF) to 5-methylTHF-polyglutamate" +xref: Reactome:R-HSA-200682 "Conversion of mitochondrial THF to THF-polyglutamate" +is_a: GO:0016881 ! acid-amino acid ligase activity +relationship: part_of GO:0046901 ! tetrahydrofolylpolyglutamate biosynthetic process + +[Term] +id: GO:0004327 +name: obsolete formaldehyde dehydrogenase (glutathione) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+." [EC:1.2.1.1] +comment: This term was made obsolete because it was derived from an EC entry (1.2.1.1) that has since been split into two entries. +synonym: "formaldehyde dehydrogenase (glutathione) activity" EXACT [] +is_obsolete: true +consider: GO:0051903 +consider: GO:0051907 + +[Term] +id: GO:0004328 +name: formamidase activity +namespace: molecular_function +alt_id: GO:0034566 +def: "Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+)." [EC:3.5.1.49, RHEA:21948] +synonym: "formamide amidohydrolase activity" EXACT [EC:3.5.1.49] +synonym: "formamide hydrolase activity" EXACT [] +xref: EC:3.5.1.49 +xref: KEGG_REACTION:R00524 +xref: MetaCyc:FORMAMIDASE-RXN +xref: RHEA:21948 +xref: UM-BBD_reactionID:r0873 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004329 +name: formate-tetrahydrofolate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate." [EC:6.3.4.3] +synonym: "10-formyl-THF synthetase activity" EXACT [GOC:vw] +synonym: "10-formyltetrahydrofolate synthetase activity" EXACT [EC:6.3.4.3] +synonym: "formate:tetrahydrofolate ligase (ADP-forming)" EXACT [EC:6.3.4.3] +synonym: "formyltetrahydrofolate synthetase activity" EXACT [EC:6.3.4.3] +synonym: "tetrahydrofolate formylase activity" EXACT [EC:6.3.4.3] +synonym: "tetrahydrofolic formylase activity" EXACT [EC:6.3.4.3] +xref: EC:6.3.4.3 +xref: MetaCyc:FORMATETHFLIG-RXN +xref: Reactome:R-HSA-200711 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate" +xref: Reactome:R-HSA-5696839 "MTHFD1L ligates HCOOH to THF to form 10-formyl-THF" +xref: Reactome:R-HSA-6801456 "MTHFD1L transforms 10-formyl-THF to HCOOH and THF" +xref: RHEA:20221 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004331 +name: fructose-2,6-bisphosphate 2-phosphatase activity +namespace: molecular_function +alt_id: GO:0004330 +def: "Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate." [EC:3.1.3.46] +synonym: "beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity" EXACT [EC:3.1.3.46] +synonym: "D-fructose-2,6-bisphosphate 2-phosphohydrolase activity" EXACT [EC:3.1.3.46] +synonym: "fructose-2,6-bisphosphatase activity" EXACT [EC:3.1.3.46] +xref: EC:3.1.3.46 +xref: MetaCyc:3.1.3.46-RXN +xref: Reactome:R-HSA-5628905 "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate" +xref: Reactome:R-HSA-70262 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate" +xref: RHEA:17289 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0004332 +name: fructose-bisphosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate." [EC:4.1.2.13] +synonym: "1,6-diphosphofructose aldolase activity" EXACT [EC:4.1.2.13] +synonym: "aldolase activity" BROAD [EC:4.1.2.13] +synonym: "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.13] +synonym: "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.13] +synonym: "diphosphofructose aldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructoaldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructose 1,6-diphosphate aldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructose 1-monophosphate aldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructose 1-phosphate aldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructose diphosphate aldolase activity" EXACT [EC:4.1.2.13] +synonym: "fructose-1,6-bisphosphate triosephosphate-lyase activity" EXACT [EC:4.1.2.13] +synonym: "ketose 1-phosphate aldolase activity" EXACT [EC:4.1.2.13] +synonym: "phosphofructoaldolase activity" EXACT [EC:4.1.2.13] +synonym: "SMALDO" RELATED [EC:4.1.2.13] +synonym: "zymohexase activity" EXACT [EC:4.1.2.13] +xref: EC:4.1.2.13 +xref: MetaCyc:F16ALDOLASE-RXN +xref: Reactome:R-HSA-71495 "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate" +xref: Reactome:R-HSA-71496 "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate" +xref: RHEA:14729 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0004333 +name: fumarate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate = fumarate + H(2)O." [EC:4.2.1.2, RHEA:12460] +synonym: "(S)-malate hydro-lyase (fumarate-forming)" EXACT [EC:4.2.1.2] +synonym: "(S)-malate hydro-lyase activity" EXACT [EC:4.2.1.2] +synonym: "fumarase activity" EXACT [EC:4.2.1.2] +synonym: "L-malate hydro-lyase activity" EXACT [EC:4.2.1.2] +xref: EC:4.2.1.2 +xref: KEGG_REACTION:R01082 +xref: MetaCyc:FUMHYDR-RXN +xref: Reactome:R-HSA-451033 "(S)-Malate <=> Fumarate + H2O" +xref: Reactome:R-HSA-70982 "Fumarate + H2O <=> (S)-Malate" +xref: RHEA:12460 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004334 +name: fumarylacetoacetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+)." [EC:3.7.1.2, RHEA:10244] +synonym: "4-fumarylacetoacetate fumarylhydrolase activity" EXACT [EC:3.7.1.2] +synonym: "beta-diketonase activity" EXACT [EC:3.7.1.2] +synonym: "fumarylacetoacetate hydrolase activity" EXACT [EC:3.7.1.2] +xref: EC:3.7.1.2 +xref: KEGG_REACTION:R01364 +xref: MetaCyc:FUMARYLACETOACETASE-RXN +xref: Reactome:R-HSA-71181 "fumarylacetoacetate => fumarate + acetoacetate" +xref: RHEA:10244 +xref: UM-BBD_reactionID:r0107 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0004335 +name: galactokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.6, RHEA:13553] +synonym: "ATP:D-galactose 1-phosphotransferase activity" EXACT [EC:2.7.1.6] +synonym: "ATP:D-galactose-1-phosphotransferase activity" EXACT [EC:2.7.1.6] +synonym: "galactokinase (phosphorylating)" EXACT [EC:2.7.1.6] +xref: EC:2.7.1.6 +xref: KEGG_REACTION:R01092 +xref: MetaCyc:GALACTOKIN-RXN +xref: Reactome:R-HSA-5610026 "Defective GALK1 does not phosphorylate Gal" +xref: Reactome:R-HSA-70355 "GALK1 phosphorylates Gal to Gal1P" +xref: RHEA:13553 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0004336 +name: galactosylceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine." [EC:3.2.1.46] +synonym: "beta-galactocerebrosidase activity" EXACT [EC:3.2.1.46] +synonym: "beta-galactosylceramidase activity" EXACT [EC:3.2.1.46] +synonym: "ceramide galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "cerebroside beta-galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "cerebroside galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "D-galactosyl-N-acylsphingosine galactohydrolase activity" EXACT [EC:3.2.1.46] +synonym: "galactocerebrosidase activity" EXACT [EC:3.2.1.46] +synonym: "galactocerebroside beta-galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "galactocerebroside galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "galactocerebroside-beta-D-galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "galactosylceramidase I" RELATED [EC:3.2.1.46] +synonym: "galactosylceramide beta-galactosidase activity" EXACT [EC:3.2.1.46] +synonym: "galactosylcerebrosidase activity" EXACT [EC:3.2.1.46] +synonym: "galcerase activity" EXACT [EC:3.2.1.46] +synonym: "lactosylceramidase activity" EXACT [EC:3.2.1.46] +synonym: "lactosylceramidase I" RELATED [EC:3.2.1.46] +xref: EC:3.2.1.46 +xref: MetaCyc:GALACTOSYLCERAMIDASE-RXN +xref: Reactome:R-HSA-1606564 "Galactocerebrosidase cleaves the galactosyl bond of galactocerebroside to form ceramide" +xref: RHEA:14297 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004337 +name: geranyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate." [EC:2.5.1.10, RHEA:19361] +comment: Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'. +synonym: "farnesyl diphosphate synthetase activity" EXACT [EC:2.5.1.10] +synonym: "farnesyl pyrophosphate synthetase activity" EXACT [] +synonym: "farnesyl-diphosphate synthase activity" EXACT [] +synonym: "farnesylpyrophosphate synthetase activity" EXACT [EC:2.5.1.10] +synonym: "FPP synthetase activity" EXACT [EC:2.5.1.10] +synonym: "geranyl transferase I" RELATED [EC:2.5.1.10] +synonym: "geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity" EXACT [EC:2.5.1.10] +synonym: "geranyltransferase activity" EXACT [EC:2.5.1.10] +xref: EC:2.5.1.10 +xref: KEGG_REACTION:R02003 +xref: MetaCyc:FPPSYN-RXN +xref: Reactome:R-HSA-191303 "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate" +xref: Reactome:R-HSA-8870469 "RGGT geranylgeranylates RAB proteins" +xref: RHEA:19361 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0004338 +name: glucan exo-1,3-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose." [EC:3.2.1.58] +synonym: "1,3-beta-glucan glucohydrolase activity" BROAD [EC:3.2.1.58] +synonym: "beta-1,3-glucan exo-hydrolase activity" EXACT [EC:3.2.1.58] +synonym: "exo (1->3)-beta-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "exo-1,3-beta-D-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "exo-1,3-beta-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "exo-1,3-beta-glucosidase activity" EXACT [EC:3.2.1.58] +synonym: "exo-beta-(1->3)-D-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "exo-beta-(1->3)-glucanohydrolase activity" EXACT [EC:3.2.1.58] +synonym: "exo-beta-1,3-D-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "exo-beta-1,3-glucanase activity" EXACT [EC:3.2.1.58] +synonym: "glucan 1,3-beta-glucosidase activity" BROAD [GOC:mah] +xref: EC:3.2.1.58 +xref: MetaCyc:3.2.1.58-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0004339 +name: glucan 1,4-alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose." [EC:3.2.1.3] +comment: Note that this term is not a child of 'alpha-glucosidase activity ; GO:0090599', because in the reaction represented by GO:0004339 results in the release of beta-D-glucose, whereas in GO:0090599 alpha-D-glucose is released. +synonym: "1,4-alpha-D-glucan glucohydrolase activity" EXACT [EC:3.2.1.3] +synonym: "amyloglucosidase activity" EXACT [EC:3.2.1.3] +synonym: "exo-1,4-alpha-glucosidase activity" EXACT [EC:3.2.1.3] +synonym: "gamma-1,4-glucan glucohydrolase activity" EXACT [EC:3.2.1.3] +synonym: "gamma-amylase activity" EXACT [EC:3.2.1.3] +synonym: "glucoamylase activity" EXACT [] +synonym: "glucose amylase activity" EXACT [EC:3.2.1.3] +synonym: "lysosomal alpha-glucosidase activity" BROAD [EC:3.2.1.3] +xref: EC:3.2.1.3 +xref: MetaCyc:3.2.1.3-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0004340 +name: glucokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate." [EC:2.7.1.2] +synonym: "ATP:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.2] +synonym: "glucokinase (phosphorylating)" EXACT [EC:2.7.1.2] +synonym: "glucose kinase activity" EXACT [EC:2.7.1.2] +xref: EC:2.7.1.2 +xref: MetaCyc:GLUCOKIN-RXN +xref: Reactome:R-HSA-5621888 "Defective HK1 does not phosphorylate Glc to form G6P" +xref: Reactome:R-HSA-5621918 "Defective GCK does not phosphorylate Glc to form G6P" +xref: Reactome:R-HSA-70420 "HK1,2,3,GCK phosphorylate Glc to form G6P" +xref: RHEA:17825 +is_a: GO:0004396 ! hexokinase activity +relationship: part_of GO:0051156 ! glucose 6-phosphate metabolic process + +[Term] +id: GO:0004341 +name: gluconolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate." [EC:3.1.1.17] +synonym: "aldonolactonase activity" EXACT [EC:3.1.1.17] +synonym: "D-glucono-1,5-lactone lactonohydrolase activity" EXACT [EC:3.1.1.17] +synonym: "glucono-delta-lactonase activity" EXACT [EC:3.1.1.17] +synonym: "gulonolactonase activity" EXACT [EC:3.1.1.17] +synonym: "lactonase activity" BROAD [EC:3.1.1.17] +xref: EC:3.1.1.17 +xref: MetaCyc:GLUCONOLACT-RXN +xref: RHEA:10440 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004342 +name: glucosamine-6-phosphate deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+)." [EC:3.5.99.6, RHEA:12172] +comment: Note that this function was formerly EC:5.3.1.10. +synonym: "2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)" EXACT [EC:3.5.99.6] +synonym: "aminodeoxyglucosephosphate isomerase activity" EXACT [EC:3.5.99.6] +synonym: "GlcN6P deaminase activity" EXACT [EC:3.5.99.6] +synonym: "glucosamine phosphate deaminase activity" EXACT [EC:3.5.99.6] +synonym: "glucosamine-6-phosphate isomerase activity" EXACT [EC:3.5.99.6] +synonym: "glucosaminephosphate isomerase" BROAD [EC:3.5.99.6] +synonym: "phosphoglucosamine isomerase activity" EXACT [EC:3.5.99.6] +synonym: "phosphoglucosaminisomerase activity" EXACT [EC:3.5.99.6] +xref: EC:3.5.99.6 +xref: KEGG_REACTION:R00765 +xref: MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN +xref: Reactome:R-HSA-6799604 "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P" +xref: RHEA:12172 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0004343 +name: glucosamine 6-phosphate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)." [EC:2.3.1.4, RHEA:10292] +synonym: "acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.4] +synonym: "aminodeoxyglucosephosphate acetyltransferase activity" EXACT [EC:2.3.1.4] +synonym: "D-glucosamine-6-P N-acetyltransferase activity" EXACT [EC:2.3.1.4] +synonym: "glucosamine 6-phosphate acetylase activity" EXACT [EC:2.3.1.4] +synonym: "glucosamine-6-phosphate acetylase activity" EXACT [EC:2.3.1.4] +synonym: "glucosamine-phosphate N-acetyltransferase activity" EXACT [] +synonym: "N-acetylglucosamine-6-phosphate synthase activity" EXACT [EC:2.3.1.4] +synonym: "phosphoglucosamine acetylase activity" EXACT [EC:2.3.1.4] +synonym: "phosphoglucosamine N-acetylase activity" EXACT [EC:2.3.1.4] +synonym: "phosphoglucosamine transacetylase activity" EXACT [EC:2.3.1.4] +xref: EC:2.3.1.4 +xref: KEGG_REACTION:R02058 +xref: MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN +xref: Reactome:R-HSA-449734 "Acetylation of glucosamine 6-phosphate to GlcNAc6P" +xref: RHEA:10292 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004344 +name: glucose dehydrogenase activity +namespace: molecular_function +alt_id: GO:0008708 +def: "Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor." [PMID:22027299] +synonym: "D-glucose:(acceptor) 1-oxidoreductase" EXACT [EC:1.1.99.10] +synonym: "D-glucose:acceptor 1-oxidoreductase" EXACT [EC:1.1.5.2] +synonym: "glucose dehydrogenase (acceptor) activity" EXACT [] +synonym: "glucose dehydrogenase (Aspergillus) activity" NARROW [EC:1.1.99.10] +synonym: "glucose dehydrogenase (decarboxylating)" EXACT [EC:1.1.99.10] +xref: EC:1.1.99.10 +xref: KEGG_REACTION:R00305 +xref: MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN +xref: RHEA:24540 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0004345 +name: glucose-6-phosphate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+." [EC:1.1.1.49] +synonym: "6-phosphoglucose dehydrogenas" RELATED [] +synonym: "6-phosphoglucose dehydrogenase activity" EXACT [] +synonym: "D-glucose 6-phosphate dehydrogenase activity" EXACT [] +synonym: "D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.49] +synonym: "Entner-doudoroff enzyme" RELATED [EC:1.1.1.49] +synonym: "G6PD activity" EXACT [EC:1.1.1.49] +synonym: "G6PDH" EXACT [] +synonym: "GDH" RELATED [] +synonym: "glucose 6-phosphate dehydrogenase (NADP) activity" EXACT [] +synonym: "glucose-6-phosphate 1-dehydrogenase activity" EXACT [] +synonym: "NADP-dependent glucose 6-phosphate dehydrogenase activity" EXACT [] +synonym: "NADP-glucose-6-phosphate dehydrogenase activity" EXACT [] +synonym: "Zwischenferment" RELATED [] +synonym: "zwischenferment" RELATED [EC:1.1.1.49] +xref: EC:1.1.1.49 +xref: MetaCyc:GLU6PDEHYDROG-RXN +xref: Reactome:R-HSA-70377 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+" +xref: RHEA:15841 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004346 +name: glucose-6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate." [EC:3.1.3.9, RHEA:16689] +synonym: "D-glucose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.9] +synonym: "glucose 6-phosphate phosphatase activity" EXACT [EC:3.1.3.9] +xref: EC:3.1.3.9 +xref: KEGG_REACTION:R00303 +xref: MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN +xref: Reactome:R-HSA-3262512 "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)" +xref: Reactome:R-HSA-3266566 "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)" +xref: Reactome:R-HSA-3274540 "Defective G6PC does not hydrolyze glucose 6-phosphate" +xref: Reactome:R-HSA-3282876 "Defective G6PC3 does not hydrolyze glucose 6-phosphate" +xref: Reactome:R-HSA-71825 "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)" +xref: RHEA:16689 +is_a: GO:0050309 ! sugar-terminal-phosphatase activity + +[Term] +id: GO:0004347 +name: glucose-6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate." [EC:5.3.1.9] +synonym: "D-glucose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.9] +synonym: "D-glucose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.9] +synonym: "glucose phosphate isomerase activity" EXACT [EC:5.3.1.9] +synonym: "hexose monophosphate isomerase activity" BROAD [EC:5.3.1.9] +synonym: "hexose phosphate isomerase activity" EXACT [EC:5.3.1.9] +synonym: "hexosephosphate isomerase activity" BROAD [EC:5.3.1.9] +synonym: "oxoisomerase activity" RELATED [EC:5.3.1.9] +synonym: "phosphoglucoisomerase activity" EXACT [EC:5.3.1.9] +synonym: "phosphoglucose isomerase activity" EXACT [EC:5.3.1.9] +synonym: "phosphohexoisomerase activity" BROAD [EC:5.3.1.9] +synonym: "phosphohexomutase activity" BROAD [EC:5.3.1.9] +synonym: "phosphohexose isomerase activity" BROAD [EC:5.3.1.9] +synonym: "phosphosaccharomutase activity" BROAD [EC:5.3.1.9] +xref: EC:5.3.1.9 +xref: MetaCyc:PGLUCISOM-RXN +xref: Reactome:R-HSA-70471 "alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate" +xref: Reactome:R-HSA-70475 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate" +xref: RHEA:11816 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004348 +name: glucosylceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine." [EC:3.2.1.45] +synonym: "acid beta-glucosidase activity" EXACT [EC:3.2.1.45] +synonym: "beta-D-glucocerebrosidase activity" EXACT [EC:3.2.1.45] +synonym: "beta-glucocerebrosidase activity" EXACT [EC:3.2.1.45] +synonym: "beta-glucosylceramidase activity" EXACT [EC:3.2.1.45] +synonym: "ceramide glucosidase activity" EXACT [EC:3.2.1.45] +synonym: "D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [EC:3.2.1.45] +synonym: "GlcCer-beta-glucosidase activity" EXACT [EC:3.2.1.45] +synonym: "glucocerebrosidase activity" EXACT [EC:3.2.1.45] +synonym: "glucosphingosine glucosylhydrolase activity" EXACT [EC:3.2.1.45] +synonym: "glucosylcerebrosidase activity" EXACT [EC:3.2.1.45] +synonym: "glucosylsphingosine beta-D-glucosidase activity" EXACT [EC:3.2.1.45] +synonym: "glucosylsphingosine beta-glucosidase activity" EXACT [EC:3.2.1.45] +synonym: "psychosine hydrolase activity" EXACT [EC:3.2.1.45] +xref: EC:3.2.1.45 +xref: MetaCyc:GLUCOSYLCERAMIDASE-RXN +xref: Reactome:R-HSA-1605591 "Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide" +xref: Reactome:R-HSA-1861788 "Glucosylceramidase 2 cleaves the glucosidic bond of glucocerebroside to form ceramide (plasma membrane)" +xref: Reactome:R-HSA-1861789 "Glucosylceramidase 3 cleaves the glucosidic bond of glucocerebroside to form ceramide (cytosol)" +xref: RHEA:13269 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004349 +name: glutamate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+)." [EC:2.7.2.11, RHEA:14877] +synonym: "ATP-L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.11] +synonym: "ATP:gamma-L-glutamate phosphotransferase activity" EXACT [EC:2.7.2.11] +synonym: "ATP:L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.11] +synonym: "gamma-glutamate kinase activity" EXACT [EC:2.7.2.11] +synonym: "gamma-glutamyl kinase activity" EXACT [EC:2.7.2.11] +synonym: "glutamate kinase activity" EXACT [EC:2.7.2.11] +xref: EC:2.7.2.11 +xref: KEGG_REACTION:R00239 +xref: MetaCyc:GLUTKIN-RXN +xref: RHEA:14877 +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0004350 +name: glutamate-5-semialdehyde dehydrogenase activity +namespace: molecular_function +alt_id: GO:0001513 +def: "Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH." [EC:1.2.1.41, RHEA:19541] +synonym: "beta-glutamylphosphate reductase activity" EXACT [EC:1.2.1.41] +synonym: "gamma-glutamyl phosphate reductase activity" EXACT [EC:1.2.1.41] +synonym: "gamma-glutamylphosphate reductase activity" EXACT [EC:1.2.1.41] +synonym: "glutamate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] +synonym: "glutamate-gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] +synonym: "glutamate-phosphate reductase activity" EXACT [] +synonym: "glutamyl-gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] +synonym: "glutamylphosphate reductase activity" EXACT [] +synonym: "L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.41] +xref: EC:1.2.1.41 +xref: KEGG_REACTION:R03313 +xref: MetaCyc:GLUTSEMIALDEHYDROG-RXN +xref: RHEA:19541 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004351 +name: glutamate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2." [EC:4.1.1.15] +synonym: "aspartic alpha-decarboxylase" BROAD [EC:4.1.1.15] +synonym: "cysteic acid decarboxylase activity" EXACT [EC:4.1.1.15] +synonym: "gamma-glutamate decarboxylase activity" EXACT [EC:4.1.1.15] +synonym: "L-aspartate-alpha-decarboxylase activity" EXACT [EC:4.1.1.15] +synonym: "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)" EXACT [EC:4.1.1.15] +synonym: "L-glutamate 1-carboxy-lyase activity" EXACT [EC:4.1.1.15] +synonym: "L-glutamate alpha-decarboxylase activity" EXACT [EC:4.1.1.15] +synonym: "L-glutamic acid decarboxylase activity" EXACT [EC:4.1.1.15] +synonym: "L-glutamic decarboxylase activity" EXACT [EC:4.1.1.15] +xref: EC:4.1.1.15 +xref: MetaCyc:GLUTDECARBOX-RXN +xref: Reactome:R-HSA-888572 "Synthesis of GABA by GAD1" +xref: Reactome:R-HSA-888577 "Synthesis of GABA by GAD2" +xref: RHEA:17785 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004352 +name: glutamate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+." [EC:1.4.1.2] +synonym: "glutamate dehydrogenase (NAD)" EXACT [EC:1.4.1.2] +synonym: "glutamate oxidoreductase activity" EXACT [EC:1.4.1.2] +synonym: "glutamic acid dehydrogenase" BROAD [EC:1.4.1.2] +synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.2] +synonym: "L-glutamate dehydrogenase" BROAD [EC:1.4.1.2] +synonym: "L-glutamate:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.2] +synonym: "NAD-dependent glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-dependent glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-linked glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-linked glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-specific glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD-specific glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] +synonym: "NAD:glutamate oxidoreductase activity" EXACT [EC:1.4.1.2] +synonym: "NADH-linked glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] +xref: EC:1.4.1.2 +xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN +xref: RHEA:15133 +is_a: GO:0004353 ! glutamate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004353 +name: glutamate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+." [EC:1.4.1.3] +comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. +synonym: "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)" RELATED [] +synonym: "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)" RELATED [] +synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.3] +synonym: "L-glutamate:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.3] +xref: EC:1.4.1.3 +xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN +xref: MetaCyc:GLUTAMATE-SYN2-PWY +xref: Reactome:R-HSA-70589 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1]" +xref: Reactome:R-HSA-70600 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1]" +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004354 +name: glutamate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+." [EC:1.4.1.4] +synonym: "dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))" EXACT [EC:1.4.1.4] +synonym: "glutamic acid dehydrogenase" BROAD [EC:1.4.1.4] +synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.4] +synonym: "L-glutamate dehydrogenase" BROAD [EC:1.4.1.4] +synonym: "L-glutamate:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.4] +synonym: "L-glutamic acid dehydrogenase activity" EXACT [EC:1.4.1.4] +synonym: "NAD(P)-glutamate dehydrogenase activity" EXACT [EC:1.4.1.4] +synonym: "NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [EC:1.4.1.4] +xref: EC:1.4.1.4 +xref: MetaCyc:GLUTDEHYD-RXN +xref: MetaCyc:GLUTSYNIII-PWY +xref: RHEA:11612 +is_a: GO:0004353 ! glutamate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004355 +name: glutamate synthase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+." [EC:1.4.1.13, RHEA:15501] +comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. +synonym: "glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity" EXACT [EC:1.4.1.13] +synonym: "glutamate synthetase (NADP) activity" EXACT [EC:1.4.1.13] +synonym: "glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity" EXACT [EC:1.4.1.13] +synonym: "glutamine-ketoglutaric aminotransferase activity" EXACT [EC:1.4.1.13] +synonym: "GOGAT activity" BROAD [EC:1.4.1.13] +synonym: "L-glutamate synthase activity" BROAD [EC:1.4.1.13] +synonym: "L-glutamate synthetase activity" BROAD [EC:1.4.1.13] +synonym: "L-glutamate:NADP+ oxidoreductase (transaminating)" EXACT [EC:1.4.1.13] +synonym: "L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity" EXACT [EC:1.4.1.13] +synonym: "NADPH GOGAT" EXACT [] +synonym: "NADPH-dependent glutamate synthase activity" EXACT [EC:1.4.1.13] +synonym: "NADPH-glutamate synthase activity" EXACT [EC:1.4.1.13] +synonym: "NADPH-linked glutamate synthase" EXACT [EC:1.4.1.13] +xref: EC:1.4.1.13 +xref: KEGG_REACTION:R00114 +xref: MetaCyc:GLUGLNSYN-PWY +xref: MetaCyc:GLUTAMATESYN-RXN +xref: MetaCyc:GLUTSYN-PWY +xref: RHEA:15501 +is_a: GO:0045181 ! glutamate synthase activity, NAD(P)H as acceptor + +[Term] +id: GO:0004356 +name: glutamate-ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate." [EC:6.3.1.2, RHEA:16169] +synonym: "glutamine synthetase activity" EXACT [] +synonym: "glutamylhydroxamic synthetase activity" EXACT [EC:6.3.1.2] +synonym: "L-glutamate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.1.2] +synonym: "L-glutamine synthetase activity" EXACT [EC:6.3.1.2] +xref: EC:6.3.1.2 +xref: KEGG_REACTION:R00253 +xref: MetaCyc:GLUTAMINESYN-RXN +xref: Reactome:R-HSA-70606 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]" +xref: RHEA:16169 +is_a: GO:0016211 ! ammonia ligase activity + +[Term] +id: GO:0004357 +name: glutamate-cysteine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate." [EC:6.3.2.2, RHEA:13285] +synonym: "gamma-glutamyl-L-cysteine synthetase activity" EXACT [EC:6.3.2.2] +synonym: "gamma-glutamylcysteine synthetase activity" EXACT [EC:6.3.2.2] +synonym: "gamma-glutamylcysteinyl synthetase activity" EXACT [EC:6.3.2.2] +synonym: "L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity" EXACT [EC:6.3.2.2] +xref: EC:6.3.2.2 +xref: KEGG_REACTION:R00894 +xref: MetaCyc:GLUTCYSLIG-RXN +xref: Reactome:R-HSA-174367 "GCL ligates L-Glu to L-Cys" +xref: Reactome:R-HSA-5602892 "Defective GCLC does not ligate L-Glu to L-Cys" +xref: RHEA:13285 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0004358 +name: glutamate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine." [EC:2.3.1.35, RHEA:15349] +synonym: "2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "acetylglutamate synthetase activity" EXACT [EC:2.3.1.35] +synonym: "acetylglutamate-acetylornithine transacetylase activity" EXACT [EC:2.3.1.35] +synonym: "acetylglutamic synthetase activity" EXACT [EC:2.3.1.35] +synonym: "acetylglutamic-acetylornithine transacetylase activity" EXACT [EC:2.3.1.35] +synonym: "acetylornithinase activity" BROAD [EC:2.3.1.35] +synonym: "acetylornithine glutamate acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "glutamate acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "N-acetyl-L-glutamate synthetase activity" BROAD [EC:2.3.1.35] +synonym: "N-acetylglutamate synthase activity" BROAD [EC:2.3.1.35] +synonym: "N-acetylglutamate synthetase activity" BROAD [EC:2.3.1.35] +synonym: "N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "ornithine acetyltransferase activity" EXACT [EC:2.3.1.35] +synonym: "ornithine transacetylase activity" EXACT [EC:2.3.1.35] +xref: EC:2.3.1.35 +xref: KEGG_REACTION:R02282 +xref: MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:15349 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004359 +name: glutaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3." [EC:3.5.1.2] +synonym: "glutaminase I" RELATED [EC:3.5.1.2] +synonym: "glutamine aminohydrolase activity" EXACT [EC:3.5.1.2] +synonym: "L-glutaminase activity" EXACT [EC:3.5.1.2] +synonym: "L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.2] +xref: EC:3.5.1.2 +xref: MetaCyc:GLUTAMIN-RXN +xref: Reactome:R-HSA-70609 "glutamine + H2O => glutamate + NH4+ [GLS]" +xref: RHEA:15889 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004360 +name: glutamine-fructose-6-phosphate transaminase (isomerizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate." [EC:2.6.1.16, RHEA:13237] +synonym: "D-fructose-6-phosphate amidotransferase activity" EXACT [EC:2.6.1.16] +synonym: "GlcN6P synthase activity" EXACT [EC:2.6.1.16] +synonym: "glucosamine 6-phosphate synthase activity" EXACT [EC:2.6.1.16] +synonym: "glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity" EXACT [EC:2.6.1.16] +synonym: "glucosamine-6-phosphate isomerase (glutamine-forming) activity" EXACT [] +synonym: "glucosamine-6-phosphate synthase activity" EXACT [EC:2.6.1.16] +synonym: "glucosaminephosphate isomerase" BROAD [EC:2.6.1.16] +synonym: "hexosephosphate aminotransferase activity" EXACT [EC:2.6.1.16] +synonym: "L-glutamine-D-fructose-6-phosphate amidotransferase activity" EXACT [EC:2.6.1.16] +synonym: "L-glutamine:D-fructose-6-phosphate isomerase (deaminating)" EXACT [EC:2.6.1.16] +xref: EC:2.6.1.16 +xref: KEGG_REACTION:R00768 +xref: MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN +xref: Reactome:R-HSA-4085027 "Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P" +xref: Reactome:R-HSA-449715 "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P" +xref: RHEA:13237 +is_a: GO:0070548 ! L-glutamine aminotransferase activity + +[Term] +id: GO:0004361 +name: glutaryl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor." [EC:1.3.8.6] +synonym: "glutaryl coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.6] +synonym: "glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)" EXACT [EC:1.3.8.6] +synonym: "glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)" EXACT [EC:1.3.8.6] +xref: EC:1.3.8.6 +xref: MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-71046 "glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2" +xref: RHEA:13389 +xref: UM-BBD_reactionID:r0198 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0004362 +name: glutathione-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+." [EC:1.8.1.7, ISBN:0198506732] +comment: Note that this function was formerly EC:1.6.4.2. +synonym: "glutathione reductase (NADPH) activity" EXACT [] +synonym: "glutathione reductase activity" EXACT [] +synonym: "glutathione S-reductase activity" EXACT [EC:1.8.1.7] +synonym: "glutathione-disulphide reductase activity" EXACT [] +synonym: "glutathione:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.7] +synonym: "GSH reductase activity" EXACT [EC:1.8.1.7] +synonym: "GSSG reductase activity" EXACT [EC:1.8.1.7] +synonym: "NADPH-glutathione reductase activity" EXACT [EC:1.8.1.7] +synonym: "NADPH-GSSG reductase activity" EXACT [EC:1.8.1.7] +synonym: "NADPH:oxidized-glutathione oxidoreductase activity" EXACT [EC:1.8.1.7] +synonym: "oxidized glutathione reduction" RELATED [] +xref: EC:1.8.1.7 +xref: MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN +xref: Reactome:R-HSA-3323079 "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+" +xref: Reactome:R-HSA-71682 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+" +xref: RHEA:11740 +is_a: GO:0015038 ! glutathione disulfide oxidoreductase activity +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0004363 +name: glutathione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate." [EC:6.3.2.3, RHEA:13557] +synonym: "gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)" EXACT [EC:6.3.2.3] +synonym: "glutathione synthetase activity" EXACT [EC:6.3.2.3] +synonym: "GSH synthetase activity" EXACT [EC:6.3.2.3] +xref: EC:6.3.2.3 +xref: KEGG_REACTION:R00497 +xref: MetaCyc:GLUTATHIONE-SYN-RXN +xref: Reactome:R-HSA-174394 "GSS:Mg2+ dimer synthesizes GSH" +xref: Reactome:R-HSA-5602901 "Defective GSS does not synthesize GSH" +xref: RHEA:13557 +is_a: GO:0016881 ! acid-amino acid ligase activity +relationship: part_of GO:0006750 ! glutathione biosynthetic process + +[Term] +id: GO:0004364 +name: glutathione transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group." [EC:2.5.1.18] +synonym: "glutathione conjugation reaction" EXACT [] +synonym: "glutathione S-alkyl transferase activity" EXACT [EC:2.5.1.18] +synonym: "glutathione S-alkyltransferase activity" EXACT [EC:2.5.1.18] +synonym: "glutathione S-aralkyltransferase activity" EXACT [EC:2.5.1.18] +synonym: "glutathione S-aryltransferase activity" EXACT [EC:2.5.1.18] +synonym: "glutathione S-transferase activity" EXACT [EC:2.5.1.18] +synonym: "RX:glutathione R-transferase activity" EXACT [EC:2.5.1.18] +synonym: "S-(hydroxyalkyl)glutathione lyase activity" EXACT [EC:2.5.1.18] +xref: EC:2.5.1.18 +xref: MetaCyc:GSHTRAN-RXN +xref: Reactome:R-HSA-176054 "GST dimers conjugate GSH with cytosolic substrates" +xref: Reactome:R-HSA-176059 "GST trimers transfer GS from GSH to luminal substrates" +xref: Reactome:R-HSA-3301943 "GSTK1 dimer transfers GS from GSH to CDNB" +xref: Reactome:R-HSA-5423653 "MGST trimers transfer GS from GSH to AFXBO and AFNBO" +xref: Reactome:R-HSA-9026777 "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1" +xref: Reactome:R-HSA-9026780 "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1" +xref: Reactome:R-HSA-9026901 "GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1" +xref: Reactome:R-HSA-9026911 "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004365 +name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+." [EC:1.2.1.12] +synonym: "3-phosphoglyceraldehyde dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.12] +synonym: "dehydrogenase, glyceraldehyde phosphate" EXACT [EC:1.2.1.12] +synonym: "GAPDH activity" EXACT [EC:1.2.1.12] +synonym: "glyceraldehyde phosphate dehydrogenase (NAD)" EXACT [EC:1.2.1.12] +synonym: "glyceraldehyde-3-P-dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "NAD-dependent glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "NADH-glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "phosphoglyceraldehyde dehydrogenase activity" EXACT [EC:1.2.1.12] +synonym: "triosephosphate dehydrogenase activity" BROAD [EC:1.2.1.12] +xref: EC:1.2.1.12 +xref: MetaCyc:GAPOXNPHOSPHN-RXN +xref: Reactome:R-HSA-70449 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+" +xref: Reactome:R-HSA-70482 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+" +xref: RHEA:10300 +is_a: GO:0043891 ! glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity + +[Term] +id: GO:0004366 +name: glycerol-3-phosphate O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate." [EC:2.3.1.15] +synonym: "3-glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "ACP:sn-glycerol-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "alpha-glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "glycerol phosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "glycerol phosphate transacylase activity" EXACT [EC:2.3.1.15] +synonym: "glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "glycerophosphate transacylase activity" EXACT [EC:2.3.1.15] +synonym: "sn-glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] +synonym: "sn-glycerol-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] +xref: EC:2.3.1.15 +xref: MetaCyc:RXN-1381 +xref: Reactome:R-HSA-1482695 "G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)" +xref: Reactome:R-HSA-549112 "G3P is acylated to 1-acyl LPA by AGPAT6" +xref: Reactome:R-HSA-75886 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]" +xref: RHEA:15325 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0004367 +name: glycerol-3-phosphate dehydrogenase [NAD+] activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+." [EC:1.1.1.8, RHEA:11092] +synonym: "alpha-glycerol phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] +synonym: "alpha-glycerophosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] +synonym: "glycerol 1-phosphate dehydrogenase activity" RELATED [EC:1.1.1.8] +synonym: "glycerol phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] +synonym: "glycerol-3-phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] +synonym: "glycerophosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] +synonym: "hydroglycerophosphate dehydrogenase activity" BROAD [EC:1.1.1.8] +synonym: "L-alpha-glycerol phosphate dehydrogenase activity" BROAD [EC:1.1.1.8] +synonym: "L-alpha-glycerophosphate dehydrogenase activity" BROAD [EC:1.1.1.8] +synonym: "L-glycerol phosphate dehydrogenase activity" BROAD [EC:1.1.1.8] +synonym: "L-glycerophosphate dehydrogenase activity" BROAD [EC:1.1.1.8] +synonym: "NAD-alpha-glycerophosphate dehydrogenase activity" EXACT [EC:1.1.1.8] +synonym: "NAD-dependent glycerol phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] +synonym: "NAD-dependent glycerol-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] +synonym: "NAD-L-glycerol-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] +synonym: "NAD-linked glycerol 3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] +synonym: "NADH-dihydroxyacetone phosphate reductase activity" RELATED [EC:1.1.1.8] +xref: EC:1.1.1.8 +xref: KEGG_REACTION:R00842 +xref: MetaCyc:1.1.1.8-RXN +xref: Reactome:R-HSA-75889 "DHAP is converted to G3P by GPD1/GPD1L" +xref: RHEA:11092 +is_a: GO:0047952 ! glycerol-3-phosphate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004368 +name: glycerol-3-phosphate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol." [EC:1.1.5.3] +comment: Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591. +synonym: "FAD-dependent glycerol-3-phosphate dehydrogenase" EXACT [EC:1.1.5.3] +synonym: "flavin-linked glycerol-3-phosphate dehydrogenase" EXACT [EC:1.1.5.3] +synonym: "glycerol-3-phosphate CoQ reductase" EXACT [EC:1.1.5.3] +synonym: "glycerophosphate dehydrogenase activity" EXACT [EC:1.1.5.3] +synonym: "L-glycerophosphate dehydrogenase activity" EXACT [EC:1.1.5.3] +synonym: "sn-glycerol-3-phosphate dehydrogenase activity" EXACT [EC:1.1.5.3] +synonym: "sn-glycerol-3-phosphate:quinone oxidoreductase activity" EXACT systematic_synonym [EC:1.1.5.3] +xref: EC:1.1.5.3 +xref: MetaCyc:RXN-9927 +xref: MetaCyc:RXN0-5260 +xref: Reactome:R-HSA-188467 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)" +xref: RHEA:18977 +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0004369 +name: glycerol-3-phosphate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2)." [EC:1.1.3.21, RHEA:18369] +synonym: "alpha-glycerophosphate oxidase activity" EXACT [EC:1.1.3.21] +synonym: "glycerol phosphate oxidase activity" EXACT [EC:1.1.3.21] +synonym: "glycerol-1-phosphate oxidase activity" EXACT [EC:1.1.3.21] +synonym: "L-alpha-glycerol-3-phosphate oxidase activity" EXACT [EC:1.1.3.21] +synonym: "L-alpha-glycerophosphate oxidase activity" EXACT [EC:1.1.3.21] +synonym: "sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity" EXACT [EC:1.1.3.21] +xref: EC:1.1.3.21 +xref: KEGG_REACTION:R00846 +xref: MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN +xref: RHEA:18369 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0004370 +name: glycerol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+)." [EC:2.7.1.30, RHEA:21644] +synonym: "ATP:glycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.30] +synonym: "ATP:glycerol-3-phosphotransferase activity" EXACT [EC:2.7.1.30] +synonym: "GK" RELATED [EC:2.7.1.30] +synonym: "glyceric kinase activity" EXACT [EC:2.7.1.30] +synonym: "glycerokinase activity" EXACT [EC:2.7.1.30] +synonym: "glycerol kinase (phosphorylating)" EXACT [EC:2.7.1.30] +xref: EC:2.7.1.30 +xref: KEGG_REACTION:R00847 +xref: MetaCyc:GLYCEROL-KIN-RXN +xref: Reactome:R-HSA-75887 "Conversion of Glycerol to Glycerol-3-phosphate" +xref: RHEA:21644 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004371 +name: glycerone kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+)." [EC:2.7.1.29, RHEA:15773] +synonym: "acetol kinase (phosphorylating)" EXACT [EC:2.7.1.29] +synonym: "acetol kinase activity" EXACT [EC:2.7.1.29] +synonym: "ATP:glycerone phosphotransferase activity" EXACT [EC:2.7.1.29] +synonym: "dihydroxyacetone kinase activity" EXACT [EC:2.7.1.29] +xref: EC:2.7.1.29 +xref: KEGG_REACTION:R01011 +xref: MetaCyc:GLYCERONE-KINASE-RXN +xref: RHEA:15773 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004372 +name: glycine hydroxymethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine." [EC:2.1.2.1] +synonym: "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] +synonym: "allothreonine aldolase activity" EXACT [EC:2.1.2.1] +synonym: "L-serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] +synonym: "serine aldolase activity" EXACT [EC:2.1.2.1] +synonym: "serine hydroxymethylase activity" EXACT [EC:2.1.2.1] +synonym: "serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] +synonym: "serine transhydroxymethylase activity" EXACT [EC:2.1.2.1] +xref: EC:2.1.2.1 +xref: MetaCyc:GLYOHMETRANS-RXN +xref: Reactome:R-HSA-200651 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine" +xref: Reactome:R-HSA-200735 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine" +xref: Reactome:R-HSA-5694137 "SHMT2 tetramer transfers CH2OH group from 5,10MTHF to glycine" +xref: Reactome:R-HSA-71249 "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly" +xref: RHEA:15481 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0004373 +name: glycogen (starch) synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1)." [EC:2.4.1.11] +synonym: "glycogen (starch) synthetase activity" EXACT [EC:2.4.1.11] +synonym: "UDP-glucose-glycogen glucosyltransferase activity" EXACT [EC:2.4.1.11] +synonym: "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.11] +synonym: "UDP-glycogen synthase activity" EXACT [EC:2.4.1.11] +synonym: "UDPG-glycogen synthetase activity" EXACT [EC:2.4.1.11] +synonym: "UDPG-glycogen transglucosylase activity" EXACT [EC:2.4.1.11] +synonym: "UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.11] +synonym: "uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [EC:2.4.1.11] +xref: EC:2.4.1.11 +xref: MetaCyc:2.4.1.11-RXN +xref: Reactome:R-HSA-3322001 "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1" +xref: Reactome:R-HSA-3322009 "GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2" +xref: Reactome:R-HSA-3322041 "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1" +xref: Reactome:R-HSA-3828061 "Defective GYS1 does not transfer glucose to growing glycogen chains" +xref: Reactome:R-HSA-3858506 "Defective GYS2 does not transfer glucose to growing glycogen chains" +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0004374 +name: obsolete glycine cleavage system +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating)." [EC:1.4.4.2, EC:2.1.2.10] +comment: This term was made obsolete because it represents a process rather than a function. +synonym: "glycine cleavage system" EXACT [] +synonym: "glycine synthase" BROAD [] +is_obsolete: true +replaced_by: GO:0019464 + +[Term] +id: GO:0004375 +name: glycine dehydrogenase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2." [EC:1.4.4.2] +synonym: "glycine cleavage system P-protein activity" NARROW [EC:1.4.4.2] +synonym: "glycine decarboxylase activity" EXACT [EC:1.4.4.2] +synonym: "glycine-cleavage complex" RELATED [EC:1.4.4.2] +synonym: "glycine-cleavage complex P-protein activity" EXACT [EC:1.4.4.2] +synonym: "glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)" EXACT [EC:1.4.4.2] +synonym: "glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)" EXACT [EC:1.4.4.2] +synonym: "P-protein" NARROW [EC:1.4.4.2] +synonym: "protein P1" NARROW [EC:1.4.4.2] +xref: EC:1.4.4.2 +xref: MetaCyc:GCVP-RXN +xref: Reactome:R-HSA-5693967 "GLDC dimer:2xPXLP decarboxylates Gly" +is_a: GO:0016642 ! oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor + +[Term] +id: GO:0004376 +name: glycolipid mannosyltransferase activity +namespace: molecular_function +alt_id: GO:0004580 +def: "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage." [GOC:ai] +synonym: "glycolipid mannosyl transferase activity" EXACT [] +xref: Reactome:R-HSA-162821 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate" +xref: Reactome:R-HSA-162873 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate" +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0004377 +name: GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage." [EC:2.4.1.131] +synonym: "GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity" EXACT [EC:2.4.1.131] +synonym: "GDP-mannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] +synonym: "GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.131] +synonym: "glycolipid 2-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.131] +synonym: "guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] +synonym: "oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] +xref: EC:2.4.1.131 +xref: MetaCyc:2.4.1.131-RXN +xref: RHEA:29523 +is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity +is_a: GO:0004376 ! glycolipid mannosyltransferase activity + +[Term] +id: GO:0004378 +name: GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage." [EC:2.4.1.132] +synonym: "GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity" EXACT systematic_synonym [EC:2.4.1.132] +synonym: "GDP-mannose-oligosaccharide-lipid mannosyltransferase II" RELATED [EC:2.4.1.132] +synonym: "GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.132] +synonym: "glycolipid 3-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.132] +synonym: "guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity" EXACT [EC:2.4.1.132] +synonym: "mannosyltransferase II activity" EXACT [EC:2.4.1.132] +xref: EC:2.4.1.132 +xref: MetaCyc:2.4.1.132-RXN +xref: RHEA:29515 +is_a: GO:0004376 ! glycolipid mannosyltransferase activity + +[Term] +id: GO:0004379 +name: glycylpeptide N-tetradecanoyltransferase activity +namespace: molecular_function +alt_id: GO:0019106 +def: "Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide." [EC:2.3.1.97] +synonym: "myristoyl-CoA-protein N-myristoyltransferase activity" EXACT [EC:2.3.1.97] +synonym: "myristoyl-coenzyme A:protein N-myristoyl transferase activity" EXACT [EC:2.3.1.97] +synonym: "myristoylating enzymes" RELATED [EC:2.3.1.97] +synonym: "N-myristoyltransferase activity" EXACT [] +synonym: "peptide N-myristoyltransferase activity" EXACT [EC:2.3.1.97] +synonym: "peptide N-tetradecanoyltransferase activity" EXACT [EC:2.3.1.97] +synonym: "protein N-myristoyltransferase activity" EXACT [EC:2.3.1.97] +synonym: "tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity" EXACT [EC:2.3.1.97] +xref: EC:2.3.1.97 +xref: MetaCyc:2.3.1.97-RXN +xref: Reactome:R-HSA-184392 "N-myristoylation of GAG polyprotein by NMT2" +xref: Reactome:R-HSA-2534087 "NMT1/2 transfer MYS to GNAT1" +is_a: GO:0016410 ! N-acyltransferase activity +is_a: GO:0019107 ! myristoyltransferase activity + +[Term] +id: GO:0004380 +name: glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose." [EC:2.4.1.40] +synonym: "A transferase activity" RELATED [EC:2.4.1.40] +synonym: "A-transferase activity" EXACT [EC:2.4.1.40] +synonym: "alpha-3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "blood-group substance A-dependent acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "blood-group substance alpha-acetyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "fucosylgalactose acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "histo-blood group A acetylgalactosaminyltransferase activity" NARROW [EC:2.4.1.40] +synonym: "histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)" EXACT [EC:2.4.1.40] +synonym: "histo-blood group A transferase activity" RELATED [EC:2.4.1.40] +synonym: "UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.40] +synonym: "UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.40] +xref: EC:2.4.1.40 +xref: MetaCyc:2.4.1.40-RXN +xref: Reactome:R-HSA-9033959 "ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC" +xref: Reactome:R-HSA-9034042 "sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec" +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0004381 +name: fucosylgalactoside 3-alpha-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose." [EC:2.4.1.37] +synonym: "[blood group substance] alpha-galactosyltransferase activity" NARROW [EC:2.4.1.37] +synonym: "B transferase activity" RELATED [EC:2.4.1.37] +synonym: "blood-group substance B-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] +synonym: "blood-group substance beta-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] +synonym: "fucosylglycoprotein 3-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity" EXACT [] +synonym: "histo-blood group B transferase activity" NARROW [EC:2.4.1.37] +synonym: "histo-blood substance B-dependent galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "histo-blood substance beta-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] +synonym: "UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +synonym: "UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] +xref: EC:2.4.1.37 +xref: MetaCyc:2.4.1.37-RXN +xref: Reactome:R-HSA-9033961 "ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC" +xref: Reactome:R-HSA-9034053 "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen" +xref: RHEA:14349 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0004382 +name: guanosine-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP + H2O = GMP + phosphate." [EC:3.6.1.42, PMID:2989286] +synonym: "GDP phosphohydrolase activity" EXACT [EC:3.6.1.42] +synonym: "GDPase activity" EXACT [EC:3.6.1.42] +synonym: "guanosine 5'-diphosphatase activity" EXACT [EC:3.6.1.6] +synonym: "guanosine diphosphatase activity" EXACT [] +xref: EC:3.6.1.42 +xref: MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN +xref: RHEA:22156 +is_a: GO:0017110 ! nucleoside-diphosphatase activity + +[Term] +id: GO:0004383 +name: guanylate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate." [EC:4.6.1.2] +synonym: "GTP diphosphate-lyase (cyclizing) activity" EXACT [EC:4.6.1.2] +synonym: "GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity" EXACT [EC:4.6.1.2] +synonym: "guanyl cyclase activity" EXACT [EC:4.6.1.2] +synonym: "guanylyl cyclase activity" EXACT [] +synonym: "receptor guanylate cyclase activity" NARROW [] +xref: EC:4.6.1.2 +xref: MetaCyc:GUANYLCYC-RXN +xref: Reactome:R-HSA-392152 "Soluble guanylate cyclase converts GTP to cGMP" +xref: Reactome:R-HSA-74885 "GUCYs converts GTP to cGMP" +xref: RHEA:13665 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016849 ! phosphorus-oxygen lyase activity +relationship: part_of GO:0006182 ! cGMP biosynthetic process + +[Term] +id: GO:0004384 +name: obsolete membrane-associated guanylate kinase +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane." [EC:2.7.4.8] +comment: This term was made obsolete because it represents a gene product and not a function. +synonym: "MAGUK" EXACT [] +synonym: "membrane-associated guanylate kinase" EXACT [] +is_obsolete: true +consider: GO:0004385 +consider: GO:0005102 +consider: GO:0007155 +consider: GO:0016021 +consider: GO:0050839 + +[Term] +id: GO:0004385 +name: guanylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + GMP = ADP + GDP." [EC:2.7.4.8] +synonym: "5'-GMP kinase activity" EXACT [EC:2.7.4.8] +synonym: "ATP:(d)GMP phosphotransferase activity" EXACT [EC:2.7.4.8] +synonym: "ATP:GMP phosphotransferase activity" EXACT [EC:2.7.4.8] +synonym: "deoxyguanylate kinase activity" RELATED [EC:2.7.4.8] +synonym: "GMP kinase activity" EXACT [EC:2.7.4.8] +synonym: "guanosine monophosphate kinase activity" EXACT [EC:2.7.4.8] +synonym: "membrane-associated guanylate kinase" NARROW [] +xref: EC:2.7.4.8 +xref: MetaCyc:GUANYL-KIN-RXN +xref: Reactome:R-HSA-110133 "(d)GDP + ADP <=> (d)GMP + ATP (GUK1)" +xref: Reactome:R-HSA-73788 "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)" +xref: RHEA:20780 +is_a: GO:0050145 ! nucleoside monophosphate kinase activity +relationship: part_of GO:0046037 ! GMP metabolic process +relationship: part_of GO:0046710 ! GDP metabolic process + +[Term] +id: GO:0004386 +name: helicase activity +namespace: molecular_function +alt_id: GO:0008026 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix." [GOC:jl] +comment: Note that most helicases catalyze processive duplex unwinding. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_yeast +synonym: "ATP-dependent helicase activity" EXACT [] +xref: Reactome:R-HSA-167097 "HIV Promoter Opening: First Transition" +xref: Reactome:R-HSA-169461 "MCM8 mediated fork unwinding" +xref: Reactome:R-HSA-169468 "MCM2-7 mediated fork unwinding" +xref: Reactome:R-HSA-5690996 "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA" +xref: Reactome:R-HSA-75949 "RNA Polymerase II Promoter Opening: First Transition" +xref: Reactome:R-HSA-9613490 "Unwinding of DNA for the nascent HIV-1 transcript: Second Transition" +xref: Reactome:R-HSA-9613494 "Unwinding of DNA for the Nascent Transcript: Second Transition" +xref: Reactome:R-HSA-9613497 "Unwinding DNA for the nascent transcript" +xref: Reactome:R-HSA-9613498 "Unwinding of DNA for the nascent HIV-1 transcript" +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0004392 +name: heme oxygenase (decyclizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O." [EC:1.14.14.18] +synonym: "haem oxidase activity" EXACT [EC:1.14.14.18] +synonym: "haem oxygenase (decyclizing) activity" EXACT [] +synonym: "haem oxygenase activity" EXACT [EC:1.14.14.18] +synonym: "heme oxidase activity" EXACT [EC:1.14.14.18] +synonym: "heme oxygenase activity" EXACT [EC:1.14.14.18] +synonym: "heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)" EXACT [EC:1.14.14.18] +synonym: "ORP33 proteins" RELATED [EC:1.14.14.18] +xref: EC:1.14.14.18 +xref: MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN +xref: Reactome:R-HSA-189398 "HMOX1,2 cleave heme" +xref: RHEA:21764 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0004394 +name: heparan sulfate 2-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate." [PMID:9153262] +synonym: "heparan-sulfate 2-O-sulphotransferase activity" EXACT [] +synonym: "heparin 2-sulfotransferase activity" RELATED [] +synonym: "heparin-sulphate 2-sulphotransferase activity" RELATED [] +xref: EC:2.8.2 +xref: Reactome:R-HSA-2076508 "HS2ST1 sulfates IdoA at C2 in heparan sulfate" +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0004395 +name: hexaprenyldihydroxybenzoate methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate." [EC:2.1.1.114] +synonym: "3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity" EXACT [EC:2.1.1.114] +synonym: "DHHB methyltransferase activity" EXACT [EC:2.1.1.114] +synonym: "DHHB-Mt activity" EXACT [EC:2.1.1.114] +synonym: "dihydroxyhexaprenylbenzoate methyltransferase activity" EXACT [EC:2.1.1.114] +synonym: "S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity" EXACT [EC:2.1.1.114] +xref: EC:2.1.1.114 +xref: MetaCyc:2.1.1.114-RXN +xref: RHEA:14121 +is_a: GO:0010420 ! 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity + +[Term] +id: GO:0004396 +name: hexokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate." [EC:2.7.1.1] +synonym: "ATP-dependent hexokinase activity" EXACT [EC:2.7.1.1] +synonym: "ATP:D-hexose 6-phosphotransferase activity" EXACT [EC:2.7.1.1] +synonym: "glucose ATP phosphotransferase activity" EXACT [EC:2.7.1.1] +synonym: "hexokinase (phosphorylating)" EXACT [EC:2.7.1.1] +synonym: "hexokinase D" RELATED [EC:2.7.1.1] +synonym: "hexokinase type I activity" NARROW [EC:2.7.1.1] +synonym: "hexokinase type II activity" NARROW [EC:2.7.1.1] +synonym: "hexokinase type III activity" NARROW [EC:2.7.1.1] +synonym: "hexokinase type IV" RELATED [EC:2.7.1.1] +synonym: "hexokinase type IV (glucokinase) activity" NARROW [EC:2.7.1.1] +synonym: "hexokinase type IV glucokinase activity" EXACT [EC:2.7.1.1] +xref: EC:2.7.1.1 +xref: MetaCyc:HEXOKINASE-RXN +xref: RHEA:22740 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0004397 +name: histidine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidine = urocanate + NH3." [EC:4.3.1.3] +synonym: "histidase activity" RELATED [GOC:hjd] +synonym: "histidinase activity" RELATED [GOC:hjd] +synonym: "histidine alpha-deaminase activity" RELATED [GOC:hjd] +synonym: "L-histidine ammonia-lyase (urocanate-forming)" EXACT [EC:4.3.1.3] +synonym: "L-histidine ammonia-lyase activity" EXACT [EC:4.3.1.3] +xref: EC:4.3.1.3 +xref: MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN +xref: Reactome:R-HSA-70899 "histidine => urocanate + NH4+" +xref: RHEA:21232 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0004398 +name: histidine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidine = histamine + CO2." [EC:4.1.1.22] +synonym: "L-histidine carboxy-lyase (histamine-forming)" EXACT [EC:4.1.1.22] +synonym: "L-histidine carboxy-lyase activity" EXACT [EC:4.1.1.22] +synonym: "L-histidine decarboxylase activity" EXACT [EC:4.1.1.22] +xref: EC:4.1.1.22 +xref: MetaCyc:HISTIDINE-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-977301 "Histidine is decarboxylated to histamine" +xref: RHEA:20840 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004399 +name: histidinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+." [EC:1.1.1.23] +xref: EC:1.1.1.23 +xref: MetaCyc:HISTALDEHYD-RXN +xref: MetaCyc:HISTOLDEHYD-RXN +xref: RHEA:20641 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004400 +name: histidinol-phosphate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate." [EC:2.6.1.9] +synonym: "glutamic-imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] +synonym: "histidine:imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] +synonym: "histidinol phosphate aminotransferase activity" EXACT [EC:2.6.1.9] +synonym: "histidinol-phosphate aminotransferase activity" EXACT [] +synonym: "IAP transaminase activity" EXACT [EC:2.6.1.9] +synonym: "imidazole acetol-phosphate transaminase activity" EXACT [EC:2.6.1.9] +synonym: "imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] +synonym: "imidazolylacetolphosphate aminotransferase activity" EXACT [EC:2.6.1.9] +synonym: "imidazolylacetolphosphate transaminase activity" EXACT [EC:2.6.1.9] +synonym: "L-histidinol phosphate aminotransferase activity" EXACT [EC:2.6.1.9] +synonym: "L-histidinol-phosphate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.9] +xref: EC:2.6.1.9 +xref: MetaCyc:HISTAMINOTRANS-RXN +xref: RHEA:23744 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004401 +name: histidinol-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate." [EC:3.1.3.15, RHEA:14465] +synonym: "histidinol phosphate phosphatase activity" EXACT [EC:3.1.3.15] +synonym: "histidinolphosphatase activity" EXACT [EC:3.1.3.15] +synonym: "histidinolphosphate phosphatase activity" EXACT [EC:3.1.3.15] +synonym: "HPpase activity" EXACT [EC:3.1.3.15] +synonym: "L-histidinol phosphate phosphatase activity" EXACT [EC:3.1.3.15] +synonym: "L-histidinol-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.15] +xref: EC:3.1.3.15 +xref: KEGG_REACTION:R03013 +xref: MetaCyc:HISTIDPHOS-RXN +xref: RHEA:14465 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0004402 +name: histone acetyltransferase activity +namespace: molecular_function +alt_id: GO:0004403 +alt_id: GO:0004404 +alt_id: GO:0004405 +alt_id: GO:0004406 +alt_id: GO:0043166 +alt_id: GO:0046971 +def: "Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone." [EC:2.3.1.48] +comment: Note that the term 'histone lysine acetyltransferase activity ; GO:0046971' was merged into this term because only lysine residues are ever acetylated in histones, and so the term was redundant. +synonym: "acetyl-CoA:histone acetyltransferase activity" EXACT [EC:2.3.1.48] +synonym: "H2A/H2B histone acetyltransferase activity" NARROW [] +synonym: "H3/H4 histone acetyltransferase activity" NARROW [] +synonym: "H4/H2 histone acetyltransferase activity" NARROW [] +synonym: "H4/H2A acetyltransferase activity" NARROW [] +synonym: "histone acetokinase activity" EXACT [EC:2.3.1.48] +synonym: "histone acetylase activity" EXACT [] +synonym: "histone lysine acetyltransferase activity" EXACT [] +synonym: "histone transacetylase activity" EXACT [EC:2.3.1.48] +synonym: "nucleosome-histone acetyltransferase activity" RELATED [EC:2.3.1.48] +xref: EC:2.3.1.48 +xref: MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-3301237 "KAT2 complexes acetylate histone H3" +xref: Reactome:R-HSA-3301345 "Elongator complex acetylates replicative histone H3, H4" +xref: Reactome:R-HSA-3318413 "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3" +xref: Reactome:R-HSA-3318415 "ATF2 acetylates histone H2B, H4" +xref: Reactome:R-HSA-3318486 "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3" +xref: Reactome:R-HSA-3321805 "NSL acetylates histone H4" +xref: Reactome:R-HSA-3321883 "MSL acetylates histone H4" +xref: Reactome:R-HSA-3321975 "NuA4 complex acetylates histone H2A, HIST1H4" +xref: Reactome:R-HSA-3451147 "KAT5 HAT complex acetylates TCF4 gene at histone H4" +xref: Reactome:R-HSA-3662318 "Type B histone acetlytransferase complex acetylates histone H4" +xref: Reactome:R-HSA-3662335 "EP300 acetylates histone H2A, H2B, H3, H4" +xref: Reactome:R-HSA-3697008 "CREBBP acetylates histone H2B, H3, H4" +xref: Reactome:R-HSA-3697920 "CLOCK acetylates lysine-10 of histone H3, H4" +xref: Reactome:R-HSA-5144542 "CLOCK acetylates lysine-15 of histone H3, H4" +xref: Reactome:R-HSA-5250938 "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9" +is_a: GO:0061733 ! peptide-lysine-N-acetyltransferase activity +relationship: part_of GO:0016573 ! histone acetylation + +[Term] +id: GO:0004407 +name: histone deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes." [EC:3.5.1.98, PMID:9893272] +xref: EC:3.5.1.98 +xref: MetaCyc:3.5.1.98-RXN +xref: Reactome:R-HSA-2545203 "Deacetylation of cleaved cohesin" +xref: Reactome:R-HSA-2545253 "Deacetylation of cohesin" +xref: Reactome:R-HSA-3769447 "HDAC1/2 containing-complexes deacetylate histones" +xref: Reactome:R-HSA-3777129 "HDAC3 containing complexes deacetylate histone" +xref: Reactome:R-HSA-3782637 "HDAC8 deacetylates histones" +xref: Reactome:R-HSA-3782655 "HDAC10 deacetylates histone" +xref: Reactome:R-HSA-427514 "eNoSC deacetylates histone H3" +xref: Reactome:R-HSA-433672 "NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3" +xref: Reactome:R-HSA-6805650 "MTA2-NuRD complex deacetylates TP53" +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0033558 ! protein deacetylase activity +relationship: part_of GO:0016575 ! histone deacetylation + +[Term] +id: GO:0004408 +name: holocytochrome-c synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: holocytochrome c = apocytochrome c + heme." [EC:4.4.1.17] +synonym: "cytochrome c heme-lyase activity" EXACT [EC:4.4.1.17] +synonym: "cytochrome c synthase activity" RELATED [EC:4.4.1.17] +synonym: "holocytochrome c synthetase activity" EXACT [EC:4.4.1.17] +synonym: "holocytochrome-c apocytochrome-c-lyase (heme-forming)" EXACT [EC:4.4.1.17] +synonym: "holocytochrome-c apocytochrome-c-lyase activity" EXACT [EC:4.4.1.17] +xref: EC:4.4.1.17 +xref: MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0004409 +name: homoaconitate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O." [EC:4.2.1.36, RHEA:15485] +synonym: "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]" RELATED [EC:4.2.1.36] +synonym: "2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.36] +synonym: "cis-homoaconitase activity" EXACT [EC:4.2.1.36] +synonym: "HACN activity" EXACT [EC:4.2.1.36] +synonym: "homoaconitase activity" EXACT [EC:4.2.1.36] +synonym: "Lys4" RELATED [EC:4.2.1.36] +synonym: "LysF" RELATED [EC:4.2.1.36] +xref: EC:4.2.1.36 +xref: KEGG_REACTION:R04371 +xref: MetaCyc:HOMOACONITATE-HYDRATASE-RXN +xref: RHEA:15485 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004410 +name: homocitrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate." [EC:2.3.3.14, RHEA:12929] +comment: Note that this function was formerly EC:4.1.3.21. +synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity" EXACT [EC:2.3.3.14] +synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)" EXACT [EC:2.3.3.14] +synonym: "acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)" EXACT [EC:2.3.3.14] +synonym: "acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity" EXACT [EC:2.3.3.14] +synonym: "homocitrate synthetase activity" EXACT [EC:2.3.3.14] +xref: EC:2.3.3.14 +xref: KEGG_REACTION:R00271 +xref: MetaCyc:HOMOCITRATE-SYNTHASE-RXN +xref: RHEA:12929 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0004411 +name: homogentisate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+)." [EC:1.13.11.5, RHEA:15449] +synonym: "homogentisate dioxygenase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisate oxidase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisate oxygenase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.5] +synonym: "homogentisic acid oxidase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisic acid oxygenase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisic oxygenase activity" EXACT [EC:1.13.11.5] +synonym: "homogentisicase activity" EXACT [EC:1.13.11.5] +xref: EC:1.13.11.5 +xref: KEGG_REACTION:R02519 +xref: MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN +xref: Reactome:R-HSA-71164 "homogentisate + O2 => maleylacetoacetate" +xref: RHEA:15449 +xref: UM-BBD_reactionID:r0105 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0004412 +name: homoserine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+." [EC:1.1.1.3] +xref: EC:1.1.1.3 +xref: MetaCyc:HOMOSERDEHYDROG-RXN +xref: RHEA:15761 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004413 +name: homoserine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+)." [EC:2.7.1.39, RHEA:13985] +synonym: "ATP:L-homoserine O-phosphotransferase activity" EXACT [EC:2.7.1.39] +synonym: "homoserine kinase (phosphorylating)" EXACT [EC:2.7.1.39] +synonym: "HSK" RELATED [EC:2.7.1.39] +xref: EC:2.7.1.39 +xref: KEGG_REACTION:R01771 +xref: MetaCyc:HOMOSERKIN-RXN +xref: RHEA:13985 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0004414 +name: homoserine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA." [EC:2.3.1.31, RHEA:13701] +synonym: "acetyl-CoA:L-homoserine O-acetyltransferase activity" EXACT [EC:2.3.1.31] +synonym: "homoserine acetyltransferase activity" EXACT [EC:2.3.1.31] +synonym: "homoserine O-trans-acetylase activity" EXACT [EC:2.3.1.31] +synonym: "homoserine transacetylase activity" BROAD [EC:2.3.1.31] +synonym: "homoserine-O-transacetylase activity" EXACT [EC:2.3.1.31] +synonym: "L-homoserine O-acetyltransferase activity" EXACT [EC:2.3.1.31] +xref: EC:2.3.1.31 +xref: KEGG_REACTION:R01776 +xref: MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN +xref: RHEA:13701 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0004415 +name: hyalurononglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate." [EC:3.2.1.35] +synonym: "chondroitinase activity" BROAD [EC:3.2.1.35] +synonym: "chondroitinase I activity" EXACT [EC:3.2.1.35] +synonym: "hyaluronate 4-glycanohydrolase activity" EXACT [EC:3.2.1.35] +synonym: "hyaluronidase activity" BROAD [EC:3.2.1.35] +synonym: "hyaluronoglucosaminidase activity" EXACT [] +synonym: "hyaluronoglucosidase activity" EXACT [EC:3.2.1.35] +xref: EC:3.2.1.35 +xref: MetaCyc:3.2.1.35-RXN +xref: Reactome:R-HSA-1793209 "HYAL1 hydrolyses Chondroitin chains" +xref: Reactome:R-HSA-2160874 "HYAL1 hydrolyses (HA)50" +xref: Reactome:R-HSA-2160892 "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments" +xref: Reactome:R-HSA-2318585 "Defective HYAL1 does not hydrolyse Chondroitin chains" +xref: Reactome:R-HSA-5693356 "CEMIP hydrolyses HA" +xref: Reactome:R-HSA-9036077 "Defective HYAL1 does not hydrolyse (HA)50" +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0004416 +name: hydroxyacylglutathione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate." [EC:3.1.2.6] +synonym: "acetoacetylglutathione hydrolase activity" EXACT [EC:3.1.2.6] +synonym: "glyoxalase II activity" EXACT [EC:3.1.2.6] +synonym: "S-(2-hydroxyacyl)glutathione hydrolase activity" EXACT [EC:3.1.2.6] +synonym: "S-2-hydroxylacylglutathione hydrolase activity" EXACT [EC:3.1.2.6] +xref: EC:3.1.2.6 +xref: MetaCyc:GLYOXII-RXN +xref: Reactome:R-HSA-6783221 "HAGH hydrolyses (R)-S-LGSH to GSH and LACT" +xref: RHEA:25245 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0004417 +name: hydroxyethylthiazole kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+)." [EC:2.7.1.50, RHEA:24212] +synonym: "4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity" EXACT [EC:2.7.1.50] +synonym: "ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity" EXACT [EC:2.7.1.50] +synonym: "hydroxyethylthiazole kinase (phosphorylating)" EXACT [EC:2.7.1.50] +xref: EC:2.7.1.50 +xref: KEGG_REACTION:R04448 +xref: MetaCyc:THIAZOLSYN3-RXN +xref: RHEA:24212 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004418 +name: hydroxymethylbilane synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+)." [EC:2.5.1.61, RHEA:13185] +comment: Note that this function was formerly EC:4.3.1.8. +synonym: "(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity" EXACT [EC:2.5.1.61] +synonym: "(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)" EXACT [EC:2.5.1.61] +synonym: "HMB-synthase activity" EXACT [EC:2.5.1.61] +synonym: "porphobilinogen ammonia-lyase (polymerizing)" EXACT [EC:2.5.1.61] +synonym: "porphobilinogen deaminase activity" EXACT [EC:2.5.1.61] +synonym: "porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)" EXACT [EC:2.5.1.61] +synonym: "pre-uroporphyrinogen synthase activity" EXACT [EC:2.5.1.61] +synonym: "uroporphyrinogen I synthase activity" NARROW [EC:2.5.1.61] +synonym: "uroporphyrinogen I synthetase activity" NARROW [EC:2.5.1.61] +synonym: "uroporphyrinogen synthase activity" EXACT [EC:2.5.1.61] +synonym: "uroporphyrinogen synthetase activity" EXACT [EC:2.5.1.61] +xref: EC:2.5.1.61 +xref: KEGG_REACTION:R00084 +xref: MetaCyc:OHMETHYLBILANESYN-RXN +xref: Reactome:R-HSA-189406 "4 PBGs bind to form HMB" +xref: RHEA:13185 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004419 +name: hydroxymethylglutaryl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA." [EC:4.1.3.4, RHEA:24404] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.4] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity" EXACT [EC:4.1.3.4] +synonym: "3-hydroxy-3-methylglutarate-CoA lyase activity" EXACT [EC:4.1.3.4] +synonym: "3-hydroxy-3-methylglutaryl CoA cleaving enzyme" RELATED [EC:4.1.3.4] +synonym: "3-hydroxy-3-methylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4] +synonym: "3-hydroxy-3-methylglutaryl-CoA lyase activity" EXACT [EC:4.1.3.4] +synonym: "HMG-CoA lyase activity" EXACT [EC:4.1.3.4] +synonym: "hydroxymethylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4] +synonym: "hydroxymethylglutaryl coenzyme A-cleaving enzyme" RELATED [EC:4.1.3.4] +xref: EC:4.1.3.4 +xref: KEGG_REACTION:R01360 +xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN +xref: Reactome:R-HSA-6788597 "HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA" +xref: Reactome:R-HSA-74180 "HMG CoA => acetoacetic acid + acetyl CoA" +xref: RHEA:24404 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0004420 +name: hydroxymethylglutaryl-CoA reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH." [EC:1.1.1.34, RHEA:15989] +synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.34] +synonym: "HMG-CoA reductase activity" BROAD [EC:1.1.1.34] +xref: EC:1.1.1.34 +xref: KEGG_REACTION:R02082 +xref: MetaCyc:1.1.1.34-RXN +xref: Reactome:R-HSA-191352 "Reduction of HMG-CoA produces mevalonate" +xref: RHEA:15989 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004421 +name: hydroxymethylglutaryl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)." [EC:2.3.3.10, RHEA:10188] +comment: Note that this function was formerly EC:4.1.3.5. +synonym: "(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity" EXACT [EC:2.3.3.10] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)" EXACT [EC:2.3.3.10] +synonym: "3-hydroxy-3-methylglutaryl CoA synthetase activity" EXACT [EC:2.3.3.10] +synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10] +synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthetase activity" EXACT [EC:2.3.3.10] +synonym: "3-hydroxy-3-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10] +synonym: "3-hydroxy-3-methylglutaryl-coenzyme A synthase activity" EXACT [EC:2.3.3.10] +synonym: "acetoacetyl coenzyme A transacetase activity" EXACT [EC:2.3.3.10] +synonym: "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.10] +synonym: "beta-hydroxy-beta-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10] +synonym: "HMG-CoA synthase activity" EXACT [EC:2.3.3.10] +synonym: "hydroxymethylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10] +synonym: "hydroxymethylglutaryl coenzyme A-condensing enzyme" RELATED [EC:2.3.3.10] +synonym: "hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity" EXACT [EC:2.3.3.10] +xref: EC:2.3.3.10 +xref: KEGG_REACTION:R01978 +xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN +xref: Reactome:R-HSA-191323 "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA" +xref: Reactome:R-HSA-73918 "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH" +xref: RHEA:10188 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0004422 +name: hypoxanthine phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.8, GOC:curators] +synonym: "6-hydroxypurine phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "6-mercaptopurine phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "guanine-hypoxanthine phosphoribosyltransferase activity" BROAD [EC:2.4.2.8] +synonym: "HGPRTase activity" EXACT [EC:2.4.2.8] +synonym: "HPRT" RELATED [EC:2.4.2.8] +synonym: "hypoxanthine-guanine phosphoribosyltransferase activity" BROAD [EC:2.4.2.8] +synonym: "IMP diphosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "IMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "IMP-GMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "IMP:diphosphate phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.8] +synonym: "inosinate pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "inosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "inosinic acid pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "inosinic pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "purine-6-thiol phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "Transphosphoribosidase activity" BROAD [EC:2.4.2.8] +xref: EC:2.4.2.8 +xref: KEGG_REACTION:R01132 +xref: MetaCyc:HYPOXANPRIBOSYLTRAN-RXN +xref: Reactome:R-HSA-74215 "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)" +xref: RHEA:17973 +is_a: GO:0106130 ! purine phosphoribosyltransferase activity + +[Term] +id: GO:0004423 +name: iduronate-2-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin." [EC:3.1.6.13] +synonym: "2-sulfo-L-iduronate 2-sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.13] +synonym: "iduronate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "iduronate sulfate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "iduronate-2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "iduronate-2-sulphatase activity" EXACT [] +synonym: "iduronide-2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "idurono-2-sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "L-iduronate 2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "L-iduronate-2-sulfate 2-sulfohydrolase activity" EXACT [EC:3.1.6.13] +synonym: "L-idurono sulfate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "L-iduronosulfatase activity" EXACT [EC:3.1.6.13] +synonym: "sulfo-L-iduronate sulfatase activity" EXACT [EC:3.1.6.13] +synonym: "sulfoiduronate sulfohydrolase activity" EXACT [EC:3.1.6.13] +xref: EC:3.1.6.13 +xref: MetaCyc:3.1.6.13-RXN +xref: Reactome:R-HSA-1678650 "IDS hydrolyses Heparan sulfate chain(5)" +xref: Reactome:R-HSA-1793182 "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)" +xref: Reactome:R-HSA-2262743 "Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain)" +xref: Reactome:R-HSA-9036046 "Defective IDS does not hydrolyse Heparan sulfate chain(5)" +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0004424 +name: imidazoleglycerol-phosphate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O." [EC:4.2.1.19, RHEA:11040] +synonym: "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]" RELATED [EC:4.2.1.19] +synonym: "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity" EXACT [EC:4.2.1.19] +synonym: "IGP dehydratase activity" EXACT [EC:4.2.1.19] +synonym: "imidazoleglycerol phosphate dehydratase activity" EXACT [] +xref: EC:4.2.1.19 +xref: KEGG_REACTION:R03457 +xref: MetaCyc:IMIDPHOSDEHYD-RXN +xref: RHEA:11040 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004425 +name: indole-3-glycerol-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O." [EC:4.1.1.48] +synonym: "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)" EXACT [EC:4.1.1.48] +synonym: "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]" RELATED [EC:4.1.1.48] +synonym: "indole-3-glycerophosphate synthase activity" EXACT [EC:4.1.1.48] +synonym: "indoleglycerol phosphate synthase activity" EXACT [EC:4.1.1.48] +synonym: "indoleglycerol phosphate synthetase activity" EXACT [EC:4.1.1.48] +xref: EC:4.1.1.48 +xref: MetaCyc:IGPSYN-RXN +xref: RHEA:23476 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004427 +name: inorganic diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate." [EC:3.6.1.1, RHEA:24576] +synonym: "diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.1] +synonym: "inorganic pyrophosphatase activity" EXACT [EC:3.6.1.1] +synonym: "pyrophosphate phosphohydrolase activity" EXACT [EC:3.6.1.1] +xref: EC:3.6.1.1 +xref: KEGG_REACTION:R00004 +xref: MetaCyc:INORGPYROPHOSPHAT-RXN +xref: Reactome:R-HSA-449937 "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]" +xref: Reactome:R-HSA-6788912 "LHPP:Mg2+ dimer hydrolyses PPi" +xref: Reactome:R-HSA-71732 "pyrophosphate + H2O => 2 orthophosphate [cytosolic]" +xref: RHEA:24576 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0004428 +name: obsolete inositol or phosphatidylinositol kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol." [GOC:hb] +comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. +synonym: "inositol or phosphatidylinositol kinase activity" EXACT [] +synonym: "inositol/phosphatidylinositol kinase activity" EXACT [] +is_obsolete: true +consider: GO:0016307 +consider: GO:0019140 +consider: GO:0052742 +consider: GO:0052813 + +[Term] +id: GO:0004430 +name: 1-phosphatidylinositol 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+)." [EC:2.7.1.67, RHEA:19877] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity" EXACT [EC:2.7.1.67] +synonym: "phosphatidylinositol 4-kinase activity" BROAD [EC:2.7.1.67] +synonym: "phosphatidylinositol kinase (phosphorylating) activity" BROAD [EC:2.7.1.67] +synonym: "phosphatidylinositol kinase activity" BROAD [EC:2.7.1.67] +synonym: "PI 4-kinase activity" EXACT [EC:2.7.1.67] +synonym: "PI kinase activity" BROAD [EC:2.7.1.67] +synonym: "PI4-kinase activity" BROAD [EC:2.7.1.67] +synonym: "PI4K" BROAD [EC:2.7.1.67] +synonym: "PI4K-alpha activity" BROAD [EC:2.7.1.67] +synonym: "PtdIns-4-kinase activity" BROAD [EC:2.7.1.67] +synonym: "type II phosphatidylinositol kinase activity" RELATED [EC:2.7.1.67] +xref: EC:2.7.1.67 +xref: KEGG_REACTION:R03361 +xref: MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN +xref: Reactome:R-HSA-1675780 "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane" +xref: Reactome:R-HSA-1675813 "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane" +xref: Reactome:R-HSA-1675883 "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane" +xref: Reactome:R-HSA-1675974 "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane" +xref: Reactome:R-HSA-1676185 "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane" +xref: RHEA:19877 +is_a: GO:0052742 ! phosphatidylinositol kinase activity + +[Term] +id: GO:0004432 +name: obsolete 1-phosphatidylinositol-4-phosphate kinase, class IA +namespace: molecular_function +def: "OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events." [PMID:11050418] +comment: This term was made obsolete because it is not a valid molecular function. +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA" EXACT [] +is_obsolete: true +consider: GO:0016308 + +[Term] +id: GO:0004433 +name: obsolete 1-phosphatidylinositol-4-phosphate kinase, class IB +namespace: molecular_function +def: "OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins." [PMID:11050418] +comment: This term was made obsolete because it is not a valid molecular function. +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IB" EXACT [] +is_obsolete: true +consider: GO:0016308 + +[Term] +id: GO:0004435 +name: phosphatidylinositol phospholipase C activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+)." [EC:3.1.4.11, RHEA:33179] +synonym: "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity" EXACT [EC:3.1.4.11] +synonym: "1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity" EXACT [EC:3.1.4.11] +synonym: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity" EXACT [] +synonym: "monophosphatidylinositol phosphodiesterase activity" BROAD [EC:3.1.4.11] +synonym: "phosphatidylinositol-4,5-bisphosphate hydrolysis" RELATED [] +synonym: "phosphoinositidase C activity" EXACT [EC:3.1.4.11] +synonym: "phosphoinositide phospholipase C activity" EXACT [EC:3.1.4.11] +synonym: "PI-PLC activity" EXACT [EC:3.1.4.11] +synonym: "triphosphoinositide phosphodiesterase activity" BROAD [EC:3.1.4.11] +xref: EC:3.1.4.11 +xref: KEGG_REACTION:R03435 +xref: MetaCyc:3.1.4.11-RXN +xref: Reactome:R-HSA-111879 "PIP2 hydrolysis" +xref: Reactome:R-HSA-167686 "Active PLCG1 hydrolyses PIP2" +xref: Reactome:R-HSA-1855177 "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane" +xref: Reactome:R-HSA-1855214 "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane" +xref: Reactome:R-HSA-1855221 "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane" +xref: Reactome:R-HSA-202407 "PLC-gamma1 hydrolyses PIP2" +xref: Reactome:R-HSA-2730847 "Hydrolysis of PIP2 by PLCG" +xref: Reactome:R-HSA-5607735 "p-Y753,Y759-PLCG2 hydrolyses PIP2" +xref: Reactome:R-HSA-622382 "PIP2 hydrolysis" +xref: Reactome:R-HSA-9032478 "EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate" +xref: RHEA:33179 +is_a: GO:0004629 ! phospholipase C activity + +[Term] +id: GO:0004436 +name: phosphatidylinositol diacylglycerol-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol." [EC:4.6.1.13] +comment: Note that this function was formerly EC:3.1.4.10. +synonym: "1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] +synonym: "1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] +synonym: "1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] +synonym: "1-phosphatidylinositol phosphodiesterase activity" EXACT [] +synonym: "monophosphatidylinositol phosphodiesterase activity" BROAD [EC:4.6.1.13] +xref: EC:4.6.1.13 +xref: MetaCyc:3.1.4.10-RXN +xref: RHEA:17093 +is_a: GO:0016849 ! phosphorus-oxygen lyase activity + +[Term] +id: GO:0004437 +name: obsolete inositol or phosphatidylinositol phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol." [GOC:hb] +comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. +synonym: "inositol or phosphatidylinositol phosphatase activity" EXACT [] +synonym: "inositol/phosphatidylinositol phosphatase activity" EXACT [] +is_obsolete: true +consider: GO:0034593 +consider: GO:0034594 +consider: GO:0052744 +consider: GO:0052745 + +[Term] +id: GO:0004438 +name: phosphatidylinositol-3-phosphatase activity +namespace: molecular_function +alt_id: GO:0016315 +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate." [EC:3.1.3.64] +comment: Note that this function includes EC:3.1.3.65. +synonym: "1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] +synonym: "D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] +synonym: "inositol 1,3-bisphosphate phosphatase activity" EXACT [EC:3.1.3.64] +synonym: "inositol-1,3-bisphosphate 3-phosphatase activity" EXACT [EC:3.1.3.64] +synonym: "inositol-1,4,-bisphosphate 3-phosphatase activity" EXACT [] +synonym: "inositol-polyphosphate 3-phosphatase activity" EXACT [EC:3.1.3.64] +synonym: "phosphatidyl-3-phosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] +xref: EC:3.1.3.64 +xref: MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN +xref: Reactome:R-HSA-1675795 "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane" +xref: Reactome:R-HSA-1675994 "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane" +xref: Reactome:R-HSA-1676114 "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane" +xref: Reactome:R-HSA-1676141 "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane" +xref: Reactome:R-HSA-6809325 "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane" +xref: Reactome:R-HSA-6809720 "PI3P is dephosphorylated to PI by MTM1:MTMR12" +xref: Reactome:R-HSA-6809777 "PI3P is dephosphorylated to PI by MTMR2:SBF1" +xref: Reactome:R-HSA-6809975 "PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane" +xref: RHEA:12316 +is_a: GO:0052744 ! phosphatidylinositol monophosphate phosphatase activity + +[Term] +id: GO:0004439 +name: phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +namespace: molecular_function +alt_id: GO:0001668 +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate." [EC:3.1.3.36, RHEA:22764] +synonym: "phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity" EXACT [EC:3.1.3.36] +synonym: "phosphatidylinositol 4,5-bisphosphate phosphatase activity" BROAD [EC:3.1.3.36] +synonym: "phosphatidylinositol-bisphosphatase activity" BROAD [EC:3.1.3.36] +synonym: "PI(4,5)P2 5-phosphatase activity" EXACT [GOC:mah, PMID:15249580] +synonym: "PtdIns(4,5)P(2) 5-phosphatase activity" EXACT [EC:3.1.3.36, GOC:mah] +synonym: "PtdIns(4,5)P2 5-phosphatase activity" EXACT [EC:3.1.3.36, GOC:mah] +synonym: "triphosphoinositide phosphatase activity" BROAD [EC:3.1.3.36] +synonym: "triphosphoinositide phosphomonoesterase activity" BROAD [EC:3.1.3.36] +xref: EC:3.1.3.36 +xref: KEGG_REACTION:R04404 +xref: MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN +xref: Reactome:R-HSA-1675824 "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane" +xref: Reactome:R-HSA-1676177 "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane" +xref: Reactome:R-HSA-8868648 "SYNJ hydrolyze PI(4,5)P2 to PI(4)P" +xref: RHEA:22764 +is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity +is_a: GO:0106019 ! phosphatidylinositol-4,5-bisphosphate phosphatase activity + +[Term] +id: GO:0004441 +name: inositol-1,4-bisphosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate." [EC:3.1.3.57, GOC:hb] +synonym: "1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.57] +synonym: "inositol polyphosphate 1-phosphatase activity" BROAD [EC:3.1.3.57] +synonym: "inositol-polyphosphate 1-phosphatase activity" EXACT [EC:3.1.3.57] +xref: EC:3.1.3.57 +xref: MetaCyc:3.1.3.57-RXN +xref: Reactome:R-HSA-1855208 "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol" +xref: RHEA:15553 +is_a: GO:0016312 ! inositol bisphosphate phosphatase activity + +[Term] +id: GO:0004442 +name: obsolete inositol-1,4,-bisphosphate 3-phosphatase +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate." [EC:3.1.3.65, GOC:go_curators] +synonym: "inositol-1,4,-bisphosphate 3-phosphatase" EXACT [] +is_obsolete: true +consider: GO:0004438 + +[Term] +id: GO:0004443 +name: obsolete inositol-1,4,-bisphosphate 4-phosphatase +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate." [EC:3.1.3.66, GOC:go_curators] +synonym: "inositol-1,4,-bisphosphate 4-phosphatase" EXACT [] +is_obsolete: true +consider: GO:0016316 + +[Term] +id: GO:0004444 +name: obsolete inositol-1,4,5-trisphosphate 1-phosphatase +namespace: molecular_function +def: "OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate." [EC:3.1.3.61, GOC:hb] +comment: This term was made obsolete because the existence of this function has not been established. +synonym: "inositol-1,4,5-trisphosphate 1-phosphatase" EXACT [] +is_obsolete: true +consider: GO:0046030 + +[Term] +id: GO:0004445 +name: inositol-polyphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [EC:3.1.3.56] +comment: Note that this is a compound function and should be replaced by 'GO:0052659 : inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity' and 'GO:0052658 : inositol-1,4,5-trisphosphate 5-phosphatase activity'. +synonym: "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity" NARROW [EC:3.1.3.56] +synonym: "5PTase activity" RELATED [EC:3.1.3.56] +synonym: "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "inosine triphosphatase activity" RELATED [EC:3.1.3.56] +synonym: "inositol 1,4,5-trisphosphate phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "inositol phosphate 5-phosphomonoesterase activity" BROAD [EC:3.1.3.56] +synonym: "inositol polyphosphate-5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "inositol triphosphate 5-phosphomonoesterase activity" RELATED [] +synonym: "inositol trisphosphate phosphomonoesterase activity" RELATED [EC:3.1.3.56] +synonym: "inositol-1,4,5-trisphosphate 5-phosphatase activity" NARROW [] +synonym: "inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "Ins(1,4,5)P(3) 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "Ins(1,4,5)P3 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "InsP3/Ins(1,3,4,5)P4 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity" BROAD [EC:3.1.3.56] +synonym: "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity" NARROW [EC:3.1.3.56] +synonym: "type I inositol-polyphosphate phosphatase activity" RELATED [EC:3.1.3.56] +synonym: "type II inositol polyphosphate 5-phosphatase activity" RELATED [] +synonym: "type II inositol-1,4,5-trisphosphate 5-phosphatase activity" NARROW [] +xref: EC:3.1.3.56 +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity + +[Term] +id: GO:0004446 +name: inositol-hexakisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate." [EC:3.1.3.62] +synonym: "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" NARROW [EC:3.1.3.62] +synonym: "inositol tetrakisphosphate phosphomonoesterase activity" RELATED [EC:3.1.3.62] +synonym: "MIPP activity" BROAD [EC:3.1.3.62] +synonym: "multiple inositol-polyphosphate phosphatase activity" BROAD [EC:3.1.3.62] +xref: EC:3.1.3.62 +xref: MetaCyc:RXN-7920 +is_a: GO:0052745 ! inositol phosphate phosphatase activity + +[Term] +id: GO:0004447 +name: iodide peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O." [EC:1.11.1.8] +synonym: "iodide peroxidase-tyrosine iodinase activity" EXACT [EC:1.11.1.8] +synonym: "iodide:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.8] +synonym: "iodinase activity" RELATED [EC:1.11.1.8] +synonym: "iodoperoxidase (heme type)" EXACT [EC:1.11.1.8] +synonym: "iodotyrosine deiodase activity" EXACT [EC:1.11.1.8] +synonym: "iodotyrosine deiodinase activity" EXACT [EC:1.11.1.8] +synonym: "monoiodotyrosine deiodinase activity" EXACT [EC:1.11.1.8] +synonym: "thyroid peroxidase activity" RELATED [EC:1.11.1.8] +synonym: "thyroperoxidase activity" RELATED [EC:1.11.1.8] +synonym: "TPO activity" RELATED [EC:1.11.1.8] +synonym: "tyrosine iodinase activity" EXACT [EC:1.11.1.8] +xref: EC:1.11.1.8 +xref: MetaCyc:IODIDE-PEROXIDASE-RXN +xref: RHEA:23336 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0004448 +name: isocitrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor." [EC:1.1.1.41, EC:1.1.1.42] +synonym: "beta-ketoglutaric-isocitric carboxylase activity" EXACT [EC:1.1.1.-] +synonym: "IDH activity" EXACT [EC:1.1.1.-] +synonym: "IDP activity" EXACT [EC:1.1.1.-] +synonym: "IDP1" RELATED [EC:1.1.1.-] +synonym: "IDP2" RELATED [EC:1.1.1.-] +synonym: "IDP3" RELATED [EC:1.1.1.-] +synonym: "isocitric acid dehydrogenase activity" EXACT [EC:1.1.1.-] +synonym: "isocitric dehydrogenase activity" EXACT [EC:1.1.1.-] +synonym: "oxalosuccinate carboxylase activity" EXACT [EC:1.1.1.-] +synonym: "oxalosuccinate decarboxylase activity" EXACT [EC:1.1.1.-] +synonym: "oxalsuccinic decarboxylase activity" EXACT [EC:1.1.1.-] +xref: MetaCyc:ISOCITDEH-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004449 +name: isocitrate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+." [EC:1.1.1.41] +synonym: "isocitrate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.41] +synonym: "isocitrate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.41] +synonym: "NAD dependent isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] +synonym: "NAD isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] +synonym: "NAD isocitric dehydrogenase activity" EXACT [EC:1.1.1.41] +synonym: "NAD-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] +synonym: "NAD-specific isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] +synonym: "nicotinamide adenine dinucleotide isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] +xref: EC:1.1.1.41 +xref: MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN +xref: Reactome:R-HSA-70967 "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]" +xref: RHEA:23632 +is_a: GO:0004448 ! isocitrate dehydrogenase activity + +[Term] +id: GO:0004450 +name: isocitrate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+." [EC:1.1.1.42] +synonym: "dual-cofactor-specific isocitrate dehydrogenase activity" RELATED [EC:1.1.1.42] +synonym: "isocitrate (NADP) dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "isocitrate dehydrogenase (NADP) activity" EXACT [EC:1.1.1.42] +synonym: "isocitrate dehydrogenase (NADP-dependent) activity" EXACT [EC:1.1.1.42] +synonym: "isocitrate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.42] +synonym: "NADP isocitric dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "NADP(+)-ICDH activity" EXACT [EC:1.1.1.42] +synonym: "NADP(+)-IDH activity" EXACT [EC:1.1.1.42] +synonym: "NADP(+)-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "NADP-dependent isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "NADP-dependent isocitric dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "NADP-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "NADP-specific isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] +synonym: "triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity" RELATED [EC:1.1.1.42] +xref: EC:1.1.1.42 +xref: MetaCyc:ISOCITDEH-RXN +xref: Reactome:R-HSA-389540 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+" +xref: Reactome:R-HSA-389550 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+" +xref: Reactome:R-HSA-450984 "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]" +xref: RHEA:19629 +is_a: GO:0004448 ! isocitrate dehydrogenase activity + +[Term] +id: GO:0004451 +name: isocitrate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: isocitrate = glyoxylate + succinate." [EC:4.1.3.1, RHEA:13245] +synonym: "ICL activity" EXACT [EC:4.1.3.1] +synonym: "isocitrase activity" EXACT [EC:4.1.3.1] +synonym: "isocitratase activity" EXACT [EC:4.1.3.1] +synonym: "isocitrate glyoxylate-lyase (succinate-forming)" EXACT [EC:4.1.3.1] +synonym: "isocitrate glyoxylate-lyase activity" EXACT [EC:4.1.3.1] +synonym: "isocitritase activity" EXACT [EC:4.1.3.1] +synonym: "threo-DS-isocitrate glyoxylate-lyase activity" EXACT [EC:4.1.3.1] +xref: EC:4.1.3.1 +xref: KEGG_REACTION:R00479 +xref: MetaCyc:ISOCIT-CLEAV-RXN +xref: RHEA:13245 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0004452 +name: isopentenyl-diphosphate delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate." [EC:5.3.3.2, RHEA:23284] +synonym: "IPP isomerase activity" EXACT [EC:5.3.3.2] +synonym: "isopentenyl-diphosphate D-isomerase activity" EXACT [] +synonym: "isopentenyl-diphosphate delta3-delta2-isomerase activity" EXACT [EC:5.3.3.2] +synonym: "isopentenylpyrophosphate delta-isomerase activity" EXACT [EC:5.3.3.2] +synonym: "isopentenylpyrophosphate isomerase activity" EXACT [EC:5.3.3.2] +synonym: "methylbutenylpyrophosphate isomerase activity" EXACT [EC:5.3.3.2] +xref: EC:5.3.3.2 +xref: KEGG_REACTION:R01123 +xref: MetaCyc:IPPISOM-RXN +xref: Reactome:R-HSA-191382 "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate" +xref: RHEA:23284 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0004453 +name: juvenile-hormone esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone." [PMID:11267890, RHEA:16393] +subset: goslim_chembl +synonym: "JH esterase activity" EXACT [EC:3.1.1.59] +synonym: "JH-esterase activity" EXACT [EC:3.1.1.59] +synonym: "juvenile hormone analog esterase activity" EXACT [EC:3.1.1.59] +synonym: "juvenile hormone carboxyesterase activity" EXACT [EC:3.1.1.59] +synonym: "methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity" EXACT [EC:3.1.1.59] +xref: EC:3.1.1.59 +xref: MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN +xref: RHEA:16393 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004454 +name: ketohexokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate." [EC:2.7.1.3] +synonym: "ATP:D-fructose 1-phosphotransferase activity" EXACT [EC:2.7.1.3] +synonym: "hepatic fructokinase activity" NARROW [EC:2.7.1.3] +synonym: "ketohexokinase (phosphorylating)" EXACT [EC:2.7.1.3] +xref: EC:2.7.1.3 +xref: MetaCyc:KETOHEXOKINASE-RXN +xref: Reactome:R-HSA-5656459 "Defective KHK does not phosphorylate beta-D-fructose" +xref: Reactome:R-HSA-70333 "KHK dimer phosphorylates Fru to Fru 1-P" +xref: RHEA:18145 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0004455 +name: ketol-acid reductoisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+." [EC:1.1.1.86] +synonym: "(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)" EXACT [EC:1.1.1.86] +synonym: "2-hydroxy-3-keto acid reductoisomerase activity" EXACT [EC:1.1.1.86] +synonym: "acetohydroxy acid isomeroreductase activity" EXACT [EC:1.1.1.86] +synonym: "acetohydroxy acid reductoisomerase activity" EXACT [EC:1.1.1.86] +synonym: "acetolactate reductoisomerase activity" EXACT [EC:1.1.1.86] +synonym: "alpha-keto-beta-hydroxylacyl reductoisomerase activity" EXACT [EC:1.1.1.86] +synonym: "dihydroxyisovalerate (isomerizing) dehydrogenase activity" EXACT [EC:1.1.1.86] +synonym: "dihydroxyisovalerate dehydrogenase (isomerizing) activity" EXACT [EC:1.1.1.86] +synonym: "isomeroreductase activity" EXACT [EC:1.1.1.86] +synonym: "ketol acid reductoisomerase activity" EXACT [EC:1.1.1.86] +synonym: "reductoisomerase activity" EXACT [EC:1.1.1.86] +xref: EC:1.1.1.86 +xref: MetaCyc:ACETOLACTREDUCTOISOM-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004456 +name: phosphogluconate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O." [EC:4.2.1.12, RHEA:17277] +synonym: "6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)" EXACT [EC:4.2.1.12] +synonym: "6-phospho-D-gluconate hydro-lyase activity" EXACT [EC:4.2.1.12] +synonym: "6-phosphogluconate dehydrase activity" EXACT [EC:4.2.1.12] +synonym: "6-phosphogluconate dehydratase activity" EXACT [EC:4.2.1.12] +synonym: "6-phosphogluconic dehydrase activity" EXACT [EC:4.2.1.12] +synonym: "gluconate 6-phosphate dehydratase activity" EXACT [EC:4.2.1.12] +synonym: "gluconate-6-phosphate dehydratase activity" EXACT [EC:4.2.1.12] +xref: EC:4.2.1.12 +xref: KEGG_REACTION:R02036 +xref: MetaCyc:PGLUCONDEHYDRAT-RXN +xref: RHEA:17277 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004457 +name: lactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate." [GOC:ai, GOC:bf] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0004458 +name: D-lactate dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c." [EC:1.1.2.4] +synonym: "(R)-lactate:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.4] +synonym: "cytochrome-dependent D-(-)-lactate dehydrogenase activity" EXACT [EC:1.1.2.4] +synonym: "D-(-)-lactic cytochrome c reductase activity" EXACT [EC:1.1.2.4] +synonym: "D-lactate (cytochrome) dehydrogenase activity" EXACT [EC:1.1.2.4] +synonym: "D-lactate ferricytochrome c oxidoreductase activity" EXACT [EC:1.1.2.4] +synonym: "D-lactate-cytochrome c reductase activity" EXACT [EC:1.1.2.4] +synonym: "lactic acid dehydrogenase activity" BROAD [EC:1.1.2.4] +xref: EC:1.1.2.4 +xref: MetaCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN +is_a: GO:0004457 ! lactate dehydrogenase activity +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0004459 +name: L-lactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+." [EC:1.1.1.27, RHEA:23444] +synonym: "L-lactic acid dehydrogenase activity" EXACT [EC:1.1.1.27] +synonym: "L-lactic dehydrogenase activity" EXACT [EC:1.1.1.27] +xref: EC:1.1.1.27 +xref: MetaCyc:L-LACTATE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-6807826 "LDHAL6B reduces PYR to LACT" +xref: Reactome:R-HSA-70510 "LDH tetramer oxidises LACT to PYR" +xref: Reactome:R-HSA-71849 "LDH tetramer reduces PYR to LACT" +xref: RHEA:23444 +is_a: GO:0004457 ! lactate dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004460 +name: L-lactate dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c." [EC:1.1.2.3] +synonym: "(S)-lactate:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.3] +synonym: "cytochrome b2" RELATED [] +synonym: "cytochrome b2 (flavin-free derivative of flavocytochrome b2)" RELATED [EC:1.1.2.3] +synonym: "dehydrogenase, lactate (cytochrome)" EXACT [EC:1.1.2.3] +synonym: "flavocytochrome b2" RELATED [EC:1.1.2.3] +synonym: "L(+)-lactate:cytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] +synonym: "L-lactate cytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] +synonym: "L-lactate cytochrome c reductase activity" EXACT [EC:1.1.2.3] +synonym: "L-lactate ferricytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] +synonym: "lactate dehydrogenase (cytochrome)" EXACT [EC:1.1.2.3] +synonym: "lactic acid dehydrogenase activity" BROAD [EC:1.1.2.3] +synonym: "lactic cytochrome c reductase activity" EXACT [EC:1.1.2.3] +xref: EC:1.1.2.3 +xref: MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN +is_a: GO:0004457 ! lactate dehydrogenase activity +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0004461 +name: lactose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose." [EC:2.4.1.22] +synonym: "lactose synthetase activity" EXACT [EC:2.4.1.22] +synonym: "UDP-galactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] +synonym: "UDP-galactose:D-glucose 4-beta-D-galactotransferase activity" EXACT [EC:2.4.1.22] +synonym: "UDPgalactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] +synonym: "UDPgalactose:D-glucose 4-beta-D-galactotransferase activity" EXACT [EC:2.4.1.22] +synonym: "uridine diphosphogalactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] +xref: EC:2.4.1.22 +xref: MetaCyc:LACTOSE-SYNTHASE-RXN +xref: Reactome:R-HSA-5653878 "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac" +xref: RHEA:12404 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0004462 +name: lactoylglutathione lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal." [EC:4.4.1.5, RHEA:19069] +synonym: "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity" EXACT [EC:4.4.1.5] +synonym: "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)" EXACT [EC:4.4.1.5] +synonym: "aldoketomutase activity" EXACT [EC:4.4.1.5] +synonym: "glyoxalase I activity" EXACT [EC:4.4.1.5] +synonym: "glyoxylase I" RELATED [EC:4.4.1.5] +synonym: "ketone-aldehyde mutase activity" EXACT [EC:4.4.1.5] +synonym: "methylglyoxalase activity" EXACT [EC:4.4.1.5] +xref: EC:4.4.1.5 +xref: KEGG_REACTION:R02530 +xref: MetaCyc:GLYOXI-RXN +xref: Reactome:R-HSA-5694071 "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH" +xref: RHEA:19069 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0004463 +name: leukotriene-A4 hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4)." [EC:3.3.2.6, RHEA:22324] +synonym: "(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity" EXACT [EC:3.3.2.6] +synonym: "leukotriene A(4) hydrolase activity" EXACT [EC:3.3.2.6] +synonym: "leukotriene A4 hydrolase activity" EXACT [EC:3.3.2.6] +synonym: "LTA-4 hydrolase activity" EXACT [EC:3.3.2.6] +synonym: "LTA4 hydrolase activity" EXACT [EC:3.3.2.6] +synonym: "LTA4H" RELATED [EC:3.3.2.6] +xref: EC:3.3.2.6 +xref: KEGG_REACTION:R03057 +xref: MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN +xref: Reactome:R-HSA-266072 "LTA4 is hydolysed to LTB4 by LTA4H" +xref: RHEA:22324 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0004464 +name: leukotriene-C4 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4)." [EC:4.4.1.20, RHEA:17617] +comment: Note that this function was EC:2.5.1.37. +synonym: "(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)" EXACT [EC:4.4.1.20] +synonym: "(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)" EXACT [EC:4.4.1.20] +synonym: "leukotriene A(4):glutathione S-leukotrienyltransferase activity" EXACT [EC:4.4.1.20] +synonym: "leukotriene A4:glutathione S-leukotrienyltransferase activity" EXACT [EC:4.4.1.20] +synonym: "leukotriene C(4) synthetase activity" EXACT [EC:4.4.1.20] +synonym: "leukotriene C4 synthetase activity" EXACT [EC:4.4.1.20] +synonym: "leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)" EXACT [EC:4.4.1.20] +synonym: "LTC(4) synthase activity" EXACT [EC:4.4.1.20] +synonym: "LTC(4) synthetase activity" EXACT [EC:4.4.1.20] +synonym: "LTC4 synthase activity" EXACT [EC:4.4.1.20] +synonym: "LTC4 synthetase activity" EXACT [EC:4.4.1.20] +xref: EC:4.4.1.20 +xref: KEGG_REACTION:R03059 +xref: MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN +xref: Reactome:R-HSA-266050 "LTA4 is converted to LTC4 by LTC4S" +xref: RHEA:17617 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0004465 +name: lipoprotein lipase activity +namespace: molecular_function +def: "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein." [EC:3.1.1.34, GOC:bf] +synonym: "clearing factor lipase activity" RELATED [EC:3.1.1.34] +synonym: "diacylglycerol hydrolase activity" EXACT [EC:3.1.1.34] +synonym: "diacylglycerol lipase activity" EXACT [EC:3.1.1.34] +synonym: "diglyceride lipase activity" EXACT [EC:3.1.1.34] +synonym: "lipemia-clearing factor" RELATED [EC:3.1.1.34] +synonym: "postheparin esterase activity" EXACT [EC:3.1.1.34] +synonym: "postheparin lipase activity" EXACT [EC:3.1.1.34] +synonym: "triacylglycero-protein acylhydrolase activity" EXACT [EC:3.1.1.34] +xref: EC:3.1.1.34 +xref: MetaCyc:LIPOPROTEIN-LIPASE-RXN +xref: Reactome:R-HSA-1482811 "DAG is hydrolyzed to 2-MAG by PNPLA2/3" +xref: Reactome:R-HSA-174757 "chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols" +xref: Reactome:R-HSA-2395768 "LPL hydrolyses TGs from mature CMs" +xref: Reactome:R-HSA-6789310 "LIPs hydrolyse TG to DAG and RCOOH" +xref: Reactome:R-HSA-8979996 "LIPs hydrolyze TG to DAG and LCFA" +xref: Reactome:R-HSA-8980228 "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA" +is_a: GO:0004806 ! triglyceride lipase activity + +[Term] +id: GO:0004466 +name: long-chain-acyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF." [EC:1.3.8.8] +synonym: "long-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.8] +synonym: "long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.8.8] +synonym: "long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.8.8] +synonym: "palmitoyl-CoA dehydrogenase activity" EXACT [EC:1.3.8.8] +synonym: "palmitoyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.8] +xref: EC:1.3.8.8 +xref: MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN +xref: RHEA:17721 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0004467 +name: long-chain fatty acid-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [EC:6.2.1.3] +synonym: "ACS3" NARROW [EC:6.2.1.3] +synonym: "acyl-activating enzyme activity" BROAD [EC:6.2.1.3] +synonym: "acyl-CoA synthetase activity" EXACT [EC:6.2.1.3] +synonym: "arachidonyl-CoA synthetase" NARROW [EC:6.2.1.3] +synonym: "FAA1" NARROW [EC:6.2.1.3] +synonym: "fatty acid thiokinase (long chain) activity" EXACT [EC:6.2.1.3] +synonym: "fatty acid thiokinase (long-chain) activity" EXACT [EC:6.2.1.3] +synonym: "LCFA synthetase activity" EXACT [EC:6.2.1.3] +synonym: "lignoceroyl-CoA synthase activity" EXACT [EC:6.2.1.3] +synonym: "long chain fatty acyl-CoA synthetase activity" EXACT [EC:6.2.1.3] +synonym: "long-chain acyl CoA synthetase activity" EXACT [EC:6.2.1.3] +synonym: "long-chain acyl-CoA synthetase activity" EXACT [] +synonym: "long-chain acyl-CoA synthetase I" NARROW [EC:6.2.1.3] +synonym: "long-chain acyl-CoA synthetase II" NARROW [EC:6.2.1.3] +synonym: "long-chain acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.3] +synonym: "long-chain fatty acid activation" RELATED [] +synonym: "long-chain fatty acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.3] +synonym: "long-chain-fatty-acid-CoA ligase activity" EXACT [] +synonym: "long-chain-fatty-acyl-CoA synthetase activity" EXACT [] +synonym: "oleoyl-CoA synthetase" NARROW [EC:6.2.1.3] +synonym: "palmitoyl coenzyme A synthetase" NARROW [EC:6.2.1.3] +synonym: "palmitoyl-CoA ligase" NARROW [EC:6.2.1.3] +synonym: "palmitoyl-CoA synthase" NARROW [EC:6.2.1.3] +synonym: "pristanoyl-CoA synthetase" NARROW [EC:6.2.1.3] +synonym: "stearoyl-CoA synthetase" NARROW [EC:6.2.1.3] +synonym: "thiokinase" RELATED [EC:6.2.1.3] +xref: EC:6.2.1.3 +xref: MetaCyc:ACYLCOASYN-RXN +xref: MetaCyc:PWY-5143 +xref: Reactome:R-HSA-159425 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)" +xref: Reactome:R-HSA-192137 "THCA is conjugated with Coenzyme A (SLC27A5 BACS)" +xref: Reactome:R-HSA-193401 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)" +xref: Reactome:R-HSA-193407 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)" +xref: Reactome:R-HSA-193424 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)" +xref: Reactome:R-HSA-193711 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)" +xref: Reactome:R-HSA-193727 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)" +xref: Reactome:R-HSA-193743 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)" +xref: Reactome:R-HSA-193766 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)" +xref: Reactome:R-HSA-201035 "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA" +xref: Reactome:R-HSA-2046085 "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA" +xref: Reactome:R-HSA-2046098 "Activation of linoleic acid to linoleoyl-CoA" +xref: Reactome:R-HSA-548843 "ACSL3,4 ligate CoA to AA to form AA-CoA" +xref: UM-BBD_enzymeID:e0025 +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity +relationship: part_of GO:0001676 ! long-chain fatty acid metabolic process + +[Term] +id: GO:0004468 +name: lysine N-acetyltransferase activity, acting on acetyl phosphate as donor +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine." [EC:2.3.1.32] +synonym: "acetyl-phosphate:L-lysine 6-N-acetyltransferase activity" EXACT [EC:2.3.1.32] +synonym: "acetyl-phosphate:L-lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.32] +synonym: "LAT activity" EXACT [EC:2.3.1.32] +synonym: "lysine acetyltransferase activity" EXACT [] +synonym: "lysine N(6)-acetyltransferase activity" EXACT [EC:2.3.1.32] +synonym: "lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.32] +xref: EC:2.3.1.32 +xref: MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-5618328 "ATAT acetylates microtubules" +xref: Reactome:R-HSA-5693001 "NAT8,8B acetylate BACE1" +xref: RHEA:14417 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0004470 +name: malic enzyme activity +namespace: molecular_function +def: "Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate." [ISBN:0198506732] +synonym: "pyruvic-malic carboxylase activity" EXACT [EC:1.1.1.39] +is_a: GO:0016615 ! malate dehydrogenase activity + +[Term] +id: GO:0004471 +name: malate dehydrogenase (decarboxylating) (NAD+) activity +namespace: molecular_function +alt_id: GO:0004472 +alt_id: GO:0016619 +def: "Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+." [EC:1.1.1.38, EC:1.1.1.39] +comment: For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.38), see 'oxaloacetate decarboxylase activity ; GO:0008948'. +synonym: "'malic' enzyme" RELATED [EC:1.1.1.38, EC:1.1.1.39] +synonym: "(S)-malate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.39] +synonym: "(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [EC:1.1.1.38] +synonym: "malate dehydrogenase (decarboxylating) activity" EXACT [EC:1.1.1.39] +synonym: "malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT [] +synonym: "NAD-linked malic enzyme" RELATED [EC:1.1.1.38] +synonym: "NAD-malic enzyme activity" BROAD [EC:1.1.1.38, EC:1.1.1.39] +synonym: "NAD-specific malic enzyme" RELATED [EC:1.1.1.38, EC:1.1.1.39] +xref: EC:1.1.1.38 +xref: EC:1.1.1.39 +xref: KEGG_REACTION:R00214 +xref: MetaCyc:1.1.1.39-RXN +xref: MetaCyc:MALIC-NAD-RXN +xref: Reactome:R-HSA-9012268 "ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR" +xref: RHEA:12653 +is_a: GO:0004470 ! malic enzyme activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004473 +name: malate dehydrogenase (decarboxylating) (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+." [EC:1.1.1.40] +comment: For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'. +synonym: "'malic' enzyme" RELATED [EC:1.1.1.40] +synonym: "(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [EC:1.1.1.40] +synonym: "L-malate:NADP oxidoreductase activity" EXACT [EC:1.1.1.40] +synonym: "malate dehydrogenase (decarboxylating, NADP)" EXACT [EC:1.1.1.40] +synonym: "malate dehydrogenase (NADP, decarboxylating)" EXACT [EC:1.1.1.40] +synonym: "NADP-linked decarboxylating malic enzyme" RELATED [EC:1.1.1.40] +synonym: "NADP-malic enzyme activity" EXACT [EC:1.1.1.40] +synonym: "NADP-specific malate dehydrogenase activity" EXACT [EC:1.1.1.40] +synonym: "NADP-specific malic enzyme" RELATED [EC:1.1.1.40] +xref: EC:1.1.1.40 +xref: KEGG_REACTION:R00216 +xref: MetaCyc:MALIC-NADP-RXN +xref: Reactome:R-HSA-9012036 "ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR" +xref: Reactome:R-HSA-9012349 "ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR" +xref: RHEA:18253 +is_a: GO:0004470 ! malic enzyme activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004474 +name: malate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+)." [EC:2.3.3.9, RHEA:18181] +comment: Note that this function was formerly EC:4.1.3.2. +synonym: "acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.9] +synonym: "glyoxylate transacetase activity" EXACT [EC:2.3.3.9] +synonym: "glyoxylate transacetylase activity" EXACT [EC:2.3.3.9] +synonym: "glyoxylic transacetase activity" EXACT [EC:2.3.3.9] +synonym: "L-malate glyoxylate-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.9] +synonym: "malate condensing enzyme activity" RELATED [EC:2.3.3.9] +synonym: "malate synthetase activity" EXACT [EC:2.3.3.9] +synonym: "malic synthetase activity" EXACT [EC:2.3.3.9] +synonym: "malic-condensing enzyme activity" RELATED [EC:2.3.3.9] +xref: EC:2.3.3.9 +xref: KEGG_REACTION:R00472 +xref: MetaCyc:MALSYN-RXN +xref: RHEA:18181 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0004475 +name: mannose-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose." [EC:2.7.7.13, RHEA:15229] +synonym: "GDP-mannose pyrophosphorylase activity" RELATED [EC:2.7.7.13] +synonym: "GTP-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] +synonym: "GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] +synonym: "GTP:mannose-1-phosphate guanylyltransferase activity" EXACT [] +synonym: "guanosine 5'-diphospho-D-mannose pyrophosphorylase activity" EXACT [EC:2.7.7.13] +synonym: "guanosine diphosphomannose pyrophosphorylase activity" EXACT [EC:2.7.7.13] +synonym: "guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] +synonym: "mannose 1-phosphate guanylyltransferase (guanosine triphosphate)" EXACT [EC:2.7.7.13] +synonym: "PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)" RELATED [EC:2.7.7.13] +xref: EC:2.7.7.13 +xref: KEGG_REACTION:R00885 +xref: MetaCyc:2.7.7.13-RXN +xref: Reactome:R-HSA-446221 "Mannose-1-phosphate converted to GDP-Mannose" +xref: RHEA:15229 +is_a: GO:0008905 ! mannose-phosphate guanylyltransferase activity + +[Term] +id: GO:0004476 +name: mannose-6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate." [EC:5.3.1.8] +synonym: "D-mannose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.8] +synonym: "D-mannose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.8] +synonym: "mannose phosphate isomerase activity" EXACT [EC:5.3.1.8] +synonym: "phosphohexoisomerase activity" BROAD [EC:5.3.1.8] +synonym: "phosphohexomutase activity" BROAD [EC:5.3.1.8] +synonym: "phosphomannoisomerase activity" EXACT [EC:5.3.1.8] +synonym: "phosphomannose isomerase activity" EXACT [EC:5.3.1.8] +xref: EC:5.3.1.8 +xref: MetaCyc:MANNPISOM-RXN +xref: Reactome:R-HSA-3781832 "Defective MPI does not isomerize Fru6P to Man6P" +xref: Reactome:R-HSA-532549 "MPI isomerises Fru6P to Man6P" +xref: RHEA:12356 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004477 +name: methenyltetrahydrofolate cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate." [EC:3.5.4.9] +synonym: "5,10-methenyl-THF cyclohydrolase activity" EXACT [GOC:vw] +synonym: "5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)" EXACT [EC:3.5.4.9] +synonym: "citrovorum factor cyclodehydrase activity" EXACT [EC:3.5.4.9] +synonym: "formyl-methenyl-methylenetetrahydrofolate synthetase (combined)" EXACT [EC:3.5.4.9] +xref: EC:3.5.4.9 +xref: MetaCyc:METHENYLTHFCYCLOHYDRO-RXN +xref: Reactome:R-HSA-200661 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O" +xref: Reactome:R-HSA-200740 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate" +xref: Reactome:R-HSA-6801328 "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF" +xref: RHEA:23700 +is_a: GO:0019238 ! cyclohydrolase activity + +[Term] +id: GO:0004478 +name: methionine adenosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine." [EC:2.5.1.6] +synonym: "adenosylmethionine synthetase activity" EXACT [EC:2.5.1.6] +synonym: "AdoMet synthetase activity" EXACT [EC:2.5.1.6] +synonym: "ATP-methionine adenosyltransferase activity" EXACT [EC:2.5.1.6] +synonym: "ATP:L-methionine S-adenosyltransferase activity" EXACT [EC:2.5.1.6] +synonym: "methionine S-adenosyltransferase activity" EXACT [EC:2.5.1.6] +synonym: "methionine-activating enzyme" RELATED [EC:2.5.1.6] +synonym: "S-adenosyl-L-methionine synthetase activity" EXACT [EC:2.5.1.6] +synonym: "S-adenosylmethionine synthase activity" EXACT [EC:2.5.1.6] +synonym: "S-adenosylmethionine synthetase activity" EXACT [EC:2.5.1.6] +xref: EC:2.5.1.6 +xref: MetaCyc:S-ADENMETSYN-RXN +xref: Reactome:R-HSA-174391 "MAT1A multimers transfer Ado from ATP to L-Met" +xref: Reactome:R-HSA-5603087 "Defective MAT1A does not transfer Ado from ATP to L-Met" +xref: Reactome:R-HSA-5603114 "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met" +xref: RHEA:21080 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004479 +name: methionyl-tRNA formyltransferase activity +namespace: molecular_function +alt_id: GO:0001718 +alt_id: GO:0070128 +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA." [EC:2.1.2.9] +synonym: "10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity" EXACT [EC:2.1.2.9] +synonym: "conversion of met-tRNAf to fmet-tRNA" RELATED [GO:curators] +synonym: "conversion of mitochondrial met-tRNAf to fmet-tRNA" RELATED [GO:curators] +synonym: "formylmethionyl-transfer ribonucleic synthetase activity" EXACT [EC:2.1.2.9] +synonym: "methionyl ribonucleic formyltransferase activity" EXACT [EC:2.1.2.9] +synonym: "methionyl-transfer ribonucleate methyltransferase activity" RELATED [EC:2.1.2.9] +synonym: "methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] +synonym: "methionyl-transfer RNA transformylase activity" EXACT [EC:2.1.2.9] +synonym: "methionyl-tRNA Met formyltransferase activity" EXACT [EC:2.1.2.9] +synonym: "methionyl-tRNA transformylase activity" EXACT [EC:2.1.2.9] +synonym: "mitochondrial N-terminal peptidyl-methionine N-formylation" RELATED [GO:curators] +synonym: "N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] +synonym: "N-terminal peptidyl-methionine N-formylation" RELATED [GO:curators] +synonym: "N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] +xref: EC:2.1.2.9 +xref: MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN +xref: Reactome:R-HSA-5389841 "MTFMT formylates methionyl-tRNA" +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0006413 ! translational initiation +relationship: part_of GO:0071951 ! conversion of methionyl-tRNA to N-formyl-methionyl-tRNA + +[Term] +id: GO:0004481 +name: methylene-fatty-acyl-phospholipid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid." [EC:2.1.1.16] +synonym: "cyclopropane synthetase activity" BROAD [EC:2.1.1.16] +synonym: "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)" EXACT [EC:2.1.1.16] +synonym: "unsaturated-phospholipid methyltransferase activity" BROAD [EC:2.1.1.16] +xref: EC:2.1.1.16 +xref: MetaCyc:2.1.1.16-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004482 +name: mRNA (guanine-N7-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine." [EC:2.1.1.56] +synonym: "guanine-7-methyltransferase activity" EXACT [EC:2.1.1.56] +synonym: "messenger ribonucleate guanine 7-methyltransferase activity" EXACT [EC:2.1.1.56] +synonym: "messenger RNA guanine 7-methyltransferase activity" EXACT [EC:2.1.1.56] +synonym: "S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity" EXACT [EC:2.1.1.56] +synonym: "S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity" EXACT [EC:2.1.1.56] +xref: EC:2.1.1.56 +xref: MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-77090 "Methylation of GMP-cap by RNA Methyltransferase" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008174 ! mRNA methyltransferase activity +relationship: part_of GO:0006370 ! 7-methylguanosine mRNA capping +relationship: part_of GO:0106005 ! RNA 5'-cap (guanine-N7)-methylation + +[Term] +id: GO:0004483 +name: mRNA (nucleoside-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine." [EC:2.1.1.57] +synonym: "messenger ribonucleate nucleoside 2'-methyltransferase activity" EXACT [EC:2.1.1.57] +synonym: "messenger RNA (nucleoside-2'-)-methyltransferase activity" EXACT [EC:2.1.1.57] +synonym: "mRNA (adenosine-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.57] +synonym: "S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.57] +xref: EC:2.1.1.57 +xref: MetaCyc:2.1.1.57-RXN +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008174 ! mRNA methyltransferase activity + +[Term] +id: GO:0004484 +name: mRNA guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue." [EC:2.7.7.50] +synonym: "GTP--RNA guanylyltransferase activity" EXACT [EC:2.7.7.50] +synonym: "GTP:mRNA guanylyltransferase activity" EXACT [] +synonym: "messenger RNA guanylyltransferase activity" EXACT [EC:2.7.7.50] +synonym: "mRNA capping enzyme activity" RELATED [EC:2.7.7.50] +synonym: "protein lambda2" RELATED [EC:2.7.7.50] +xref: EC:2.7.7.50 +xref: MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN +xref: Reactome:R-HSA-77081 "Formation of the CE:GMP intermediate complex" +xref: Reactome:R-HSA-77083 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA" +is_a: GO:0008192 ! RNA guanylyltransferase activity + +[Term] +id: GO:0004485 +name: methylcrotonoyl-CoA carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate." [EC:6.4.1.4, RHEA:13589] +synonym: "3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.4] +synonym: "beta-methylcrotonyl CoA carboxylase activity" EXACT [EC:6.4.1.4] +synonym: "beta-methylcrotonyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.4] +synonym: "beta-methylcrotonyl-CoA carboxylase activity" EXACT [EC:6.4.1.4] +synonym: "MCCC activity" EXACT [GOC:bf] +synonym: "methylcrotonyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.4] +synonym: "methylcrotonyl-CoA carboxylase activity" EXACT [EC:6.4.1.4] +xref: EC:6.4.1.4 +xref: KEGG_REACTION:R04138 +xref: MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN +xref: Reactome:R-HSA-508308 "beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA]" +xref: Reactome:R-HSA-70773 "beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA]" +xref: RHEA:13589 +is_a: GO:0016421 ! CoA carboxylase activity + +[Term] +id: GO:0004486 +name: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+." [EC:1.5.1.15] +synonym: "5,10-methylene-THF dehydrogenase activity" EXACT [GOC:vw] +synonym: "N5,N10-methylenetetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.5] +xref: EC:1.5.1.5 +xref: Reactome:R-HSA-200644 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+" +xref: Reactome:R-HSA-200718 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+" +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004487 +name: methylenetetrahydrofolate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH." [EC:1.5.1.15, RHEA:22892] +synonym: "5,10-methylenetetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.5] +synonym: "5,10-methylenetetrahydrofolate:NAD+ oxidoreductase" EXACT [EC:1.5.1.15] +xref: EC:1.5.1.15 +xref: KEGG_REACTION:R01218 +xref: MetaCyc:1.5.1.15-RXN +xref: Reactome:R-HSA-6801462 "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF" +xref: RHEA:22892 +is_a: GO:0004486 ! methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004488 +name: methylenetetrahydrofolate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH." [EC:1.5.1.5, RHEA:22812] +synonym: "5,10-methylenetetrahydrofolate:NADP oxidoreductase activity" EXACT [EC:1.5.1.5] +synonym: "5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.5] +xref: EC:1.5.1.5 +xref: KEGG_REACTION:R01220 +xref: MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN +xref: RHEA:22812 +is_a: GO:0004486 ! methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004489 +name: methylenetetrahydrofolate reductase (NAD(P)H) activity +namespace: molecular_function +alt_id: GO:0008702 +def: "Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+." [EC:1.5.1.20] +synonym: "5,10-CH(2)-H(4)folate reductase activity" EXACT [EC:1.5.1.20] +synonym: "5,10-CH2-H4folate reductase activity" EXACT [EC:1.5.1.20] +synonym: "5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [EC:1.5.1.20] +synonym: "5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [] +synonym: "5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [] +synonym: "5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [EC:1.5.1.20] +synonym: "5,10-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] +synonym: "5,10-methylenetetrahydrofolic acid reductase activity" BROAD [EC:1.5.1.20] +synonym: "5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.20] +synonym: "MetF" RELATED [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate reductase (NADPH2)" EXACT [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [EC:1.5.1.20] +synonym: "methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] +synonym: "methylenetetrahydrofolic acid reductase activity" BROAD [EC:1.5.1.20] +synonym: "MTHFR activity" BROAD [EC:1.5.1.20] +synonym: "N(5),N(10)-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] +synonym: "N(5,10)-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] +synonym: "N5,10-methylenetetrahydrofolate reductase activity" EXACT [EC:1.5.1.20] +synonym: "N5,N10-methylenetetrahydrofolate reductase activity" EXACT [EC:1.5.1.20] +xref: EC:1.5.1.20 +xref: KEGG_REACTION:R01224 +xref: KEGG_REACTION:R07168 +xref: MetaCyc:1.5.1.20-RXN +xref: Reactome:R-HSA-200676 "5,10-methyleneTHF polyglutamate + NADPH + H+ => 5-methylTHF polyglutamate + NADP+" +xref: RHEA:19817 +xref: RHEA:19821 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004490 +name: methylglutaconyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O." [EC:4.2.1.18, RHEA:21536] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)" EXACT [EC:4.2.1.18] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity" EXACT [EC:4.2.1.18] +synonym: "3-methylglutaconyl CoA hydratase activity" EXACT [EC:4.2.1.18] +synonym: "methylglutaconase activity" EXACT [EC:4.2.1.18] +synonym: "methylglutaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.18] +xref: EC:4.2.1.18 +xref: KEGG_REACTION:R02085 +xref: MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN +xref: Reactome:R-HSA-70785 "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA" +xref: RHEA:21536 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004491 +name: methylmalonate-semialdehyde dehydrogenase (acylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+." [EC:1.2.1.27] +synonym: "2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)" EXACT [EC:1.2.1.27] +synonym: "MMSA dehydrogenase activity" EXACT [EC:1.2.1.27] +synonym: "MSDH activity" EXACT [EC:1.2.1.27] +xref: EC:1.2.1.27 +xref: MetaCyc:1.2.1.27-RXN +xref: Reactome:R-HSA-70893 "methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+" +xref: RHEA:20804 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004492 +name: methylmalonyl-CoA decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2." [EC:7.2.4.3] +synonym: "(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity" EXACT [EC:7.2.4.3] +synonym: "(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)" EXACT [EC:7.2.4.3] +synonym: "(S)-methylmalonyl-CoA carboxy-lyase activity" EXACT [EC:7.2.4.3] +synonym: "methylmalonyl-coenzyme A decarboxylase activity" EXACT [EC:7.2.4.3] +xref: EC:7.2.4.3 +xref: MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN +xref: RHEA:21396 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004493 +name: methylmalonyl-CoA epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA." [EC:5.1.99.1, RHEA:20553] +synonym: "2-methyl-3-oxopropanoyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.1] +synonym: "DL-methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] +synonym: "methylmalonyl coenzyme A racemase activity" EXACT [EC:5.1.99.1] +synonym: "methylmalonyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.1] +synonym: "methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] +xref: EC:5.1.99.1 +xref: KEGG_REACTION:R02765 +xref: MetaCyc:METHYLMALONYL-COA-EPIM-RXN +xref: Reactome:R-HSA-71020 "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA" +xref: RHEA:20553 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0004494 +name: methylmalonyl-CoA mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA." [EC:5.4.99.2, RHEA:22888] +synonym: "(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.2] +synonym: "(R)-methylmalonyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.2] +synonym: "(S)-methylmalonyl-CoA mutase activity" EXACT [EC:5.4.99.2] +synonym: "methylmalonyl coenzyme A carbonylmutase activity" EXACT [EC:5.4.99.2] +synonym: "methylmalonyl coenzyme A mutase activity" EXACT [EC:5.4.99.2] +synonym: "methylmalonyl-CoA CoA-carbonyl mutase activity" EXACT [EC:5.4.99.2] +xref: EC:5.4.99.2 +xref: KEGG_REACTION:R00833 +xref: MetaCyc:METHYLMALONYL-COA-MUT-RXN +xref: Reactome:R-HSA-3322971 "Defective MUT does not isomerise L-MM-CoA to SUCC-CoA" +xref: Reactome:R-HSA-71010 "MUT isomerises L-MM-CoA to SUCC-CoA" +xref: RHEA:22888 +xref: UM-BBD_reactionID:r0922 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0004495 +name: mevaldate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor." [EC:1.1.1.32, EC:1.1.1.33] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004496 +name: mevalonate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+)." [EC:2.7.1.36, RHEA:17065] +synonym: "ATP:(R)-mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] +synonym: "ATP:mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] +synonym: "mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] +synonym: "mevalonate kinase (phosphorylating)" EXACT [EC:2.7.1.36] +synonym: "mevalonate phosphokinase activity" EXACT [EC:2.7.1.36] +synonym: "mevalonic acid kinase activity" EXACT [EC:2.7.1.36] +synonym: "mevalonic kinase activity" EXACT [EC:2.7.1.36] +synonym: "MVA kinase activity" EXACT [EC:2.7.1.36] +xref: EC:2.7.1.36 +xref: KEGG_REACTION:R02245 +xref: MetaCyc:MEVALONATE-KINASE-RXN +xref: Reactome:R-HSA-191380 "Mevalonate is phosphorylated to mevalonate-5-phosphate" +xref: RHEA:17065 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004497 +name: monooxygenase activity +namespace: molecular_function +def: "Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water." [ISBN:0198506732] +subset: goslim_pir +synonym: "hydroxylase activity" RELATED [GOC:mah, GOC:vk] +xref: Reactome:R-HSA-143468 "MEOS oxidizes ethanol to acetaldehyde" +xref: Reactome:R-HSA-156526 "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO" +xref: Reactome:R-HSA-211882 "CYP3A7 can 6beta-hydroxylate testosterone" +xref: Reactome:R-HSA-211904 "CYP4F12 18-hydroxylates ARA" +xref: Reactome:R-HSA-211910 "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation" +xref: Reactome:R-HSA-211919 "CYP4F8 19-hydroxylates PGH2" +xref: Reactome:R-HSA-211924 "CYP4B1 12-hydroxylates ARA" +xref: Reactome:R-HSA-211929 "CYP2C19 5-hydroxylates omeprazole" +xref: Reactome:R-HSA-211948 "CYP3A4 can N-demethylate loperamide" +xref: Reactome:R-HSA-211951 "CYP1B1 4-hydroxylates EST17b" +xref: Reactome:R-HSA-211959 "CYP3A43 6b-hydroxylates TEST" +xref: Reactome:R-HSA-211960 "CYP2U1 19-hydroxylates ARA" +xref: Reactome:R-HSA-211962 "CYP4F11 16-hydroxylates 3OH-PALM" +xref: Reactome:R-HSA-211968 "CYP2W1 oxidises INDOL" +xref: Reactome:R-HSA-211988 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation" +xref: Reactome:R-HSA-211991 "Cyclophosphamide is 4-hydroxylated by CYP2B6" +xref: Reactome:R-HSA-212004 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation" +xref: Reactome:R-HSA-212005 "CYP2F1 dehydrogenates 3-methylindole" +xref: Reactome:R-HSA-213175 "CYP3A4,5 oxidise AFB1 to AFXBO" +xref: Reactome:R-HSA-215526 "CYP4F3 20-hydroxylates LTB4" +xref: Reactome:R-HSA-2161795 "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)" +xref: Reactome:R-HSA-2161814 "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)" +xref: Reactome:R-HSA-2161890 "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)" +xref: Reactome:R-HSA-2161899 "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)" +xref: Reactome:R-HSA-2161940 "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)" +xref: Reactome:R-HSA-2162191 "DMPhOH is hydroxylated to MDMQ10H2 by DMPhOH monooxygenase" +xref: Reactome:R-HSA-217258 "FMO2:FAD:Mg2+ S-oxidises MTZ" +xref: Reactome:R-HSA-5423647 "CYP2A13 oxidises AFM1 to AFM1E" +xref: Reactome:R-HSA-5423664 "CYP3A4,5 hydroxylates AFB1 to AFQ1" +xref: Reactome:R-HSA-5423672 "CYP1A2, 3A4 oxidise AFB1 to AFNBO" +xref: Reactome:R-HSA-5423678 "CYP1A2 hydroxylates AFB1 to AFM1" +xref: Reactome:R-HSA-5602242 "Defective CYP2U1 does not omega-hydroxylate ARA" +xref: Reactome:R-HSA-5602272 "Defective CYP4F22 does not 20-hydroxylate TrXA3" +xref: Reactome:R-HSA-5602295 "CYP4F22 20-hydroxylates TrXA3" +xref: Reactome:R-HSA-5605147 "Defective CYP1B1 does not 4-hydroxylate EST17b" +xref: Reactome:R-HSA-5662662 "Tyrosinase oxidises tyrosine to dopaquinone" +xref: Reactome:R-HSA-5662692 "Dopa is oxidized to dopaquinone by TYR" +xref: Reactome:R-HSA-5663050 "DHI and DHICA polymerise forming eumelanin" +xref: Reactome:R-HSA-6786239 "CYP4V2 omega-hydroxylates DHA to HDoHE" +xref: Reactome:R-HSA-76354 "Vinyl chloride is oxidized to 2-Chloroethylene oxide" +xref: Reactome:R-HSA-76373 "N-hydroxylation of 4-aminobiphenyl" +xref: Reactome:R-HSA-76386 "CYP1A2 S-demethylates 6MMP" +xref: Reactome:R-HSA-76397 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI)" +xref: Reactome:R-HSA-76416 "Benzene is hydroxylated to phenol" +xref: Reactome:R-HSA-76426 "N-atom dealkylation of caffeine" +xref: Reactome:R-HSA-76434 "Dehalogenation of carbon tetrachloride to form a free radical" +xref: Reactome:R-HSA-76456 "O-atom dealkylation of dextromethorphan" +xref: Reactome:R-HSA-76466 "CYP4A11 12-hydroxylates DDCX" +xref: Reactome:R-HSA-76472 "Ethylene is oxidized to Ethylene oxide by CYP1A1" +xref: Reactome:R-HSA-76475 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" +xref: Reactome:R-HSA-8865107 "MICAL1 produces NADP+, H2O2" +xref: Reactome:R-HSA-9018874 "CYP monooxygenates EPA to 18(S)-HpEPE" +xref: Reactome:R-HSA-9027042 "CPY4 -oxidises 14(S)-HDHA to MaR-L1" +xref: Reactome:R-HSA-9027043 "CYPs hydroxylate DHA to 14(R)-HDHA" +xref: Reactome:R-HSA-9027044 "CYP4 -oxidises 14(R)-HDHA to MaR-L2" +xref: Reactome:R-HSA-9027302 "CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA" +xref: Reactome:R-HSA-9027321 "CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA" +xref: Reactome:R-HSA-9037761 "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0004498 +name: calcidiol 1-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+)." [EC:1.14.15.18, RHEA:20573] +synonym: "1-hydroxylase-25-hydroxyvitamin D3 activity" RELATED [EC:1.14.15.18] +synonym: "25-hydroxy D3-1alpha-hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "25-hydroxy vitamin D3 1-alpha-hydroxylase activity" EXACT [] +synonym: "25-hydroxycholecalciferol 1-hydroxylase activity" EXACT [] +synonym: "25-hydroxycholecalciferol 1-monooxygenase activity" EXACT [EC:1.14.15.18] +synonym: "25-hydroxycholecalciferol 1alpha-hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "25-hydroxycholecalciferol-1-hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "25-hydroxyvitamin D-1 alpha hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "25-hydroxyvitamin D3 1alpha-hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "25-OHD-1 alpha-hydroxylase activity" EXACT [EC:1.14.15.18] +synonym: "calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)" EXACT [] +synonym: "cytochrome P450 CYP27B" NARROW [] +xref: EC:1.14.15.18 +xref: KEGG_REACTION:R03610 +xref: MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-209868 "CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D" +xref: Reactome:R-HSA-5602186 "Defective CYP27B1 does not hydroxylate CDL" +xref: RHEA:20573 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +relationship: part_of GO:0036378 ! calcitriol biosynthetic process from calciol + +[Term] +id: GO:0004499 +name: N,N-dimethylaniline monooxygenase activity +namespace: molecular_function +alt_id: GO:0047076 +def: "Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O." [EC:1.14.13.8] +synonym: "1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity" EXACT [EC:1.13.12.11] +synonym: "dimethylaniline monooxygenase (N-oxide-forming) activity" EXACT [] +synonym: "dimethylaniline N-oxidase activity" EXACT [EC:1.13.12.11] +synonym: "dimethylaniline oxidase activity" EXACT [EC:1.13.12.11] +synonym: "DMA oxidase activity" EXACT [EC:1.13.12.11] +synonym: "FAD-containing monooxygenase activity" RELATED [EC:1.13.12.11] +synonym: "flavin mixed function oxidase activity" RELATED [EC:1.13.12.11] +synonym: "flavin monooxygenase activity" RELATED [EC:1.13.12.11] +synonym: "flavin-containing monooxygenase activity" BROAD [EC:1.13.12.11] +synonym: "FMO activity" RELATED [EC:1.13.12.11] +synonym: "FMO-I" RELATED [EC:1.13.12.11] +synonym: "FMO-II" RELATED [EC:1.13.12.11] +synonym: "FMO1" RELATED [EC:1.13.12.11] +synonym: "FMO2" RELATED [EC:1.13.12.11] +synonym: "FMO3" RELATED [EC:1.13.12.11] +synonym: "FMO4" RELATED [EC:1.13.12.11] +synonym: "FMO5" RELATED [EC:1.13.12.11] +synonym: "methylphenyltetrahydropyridine N-monooxygenase activity" EXACT [] +synonym: "mixed-function amine oxidase activity" RELATED [EC:1.13.12.11] +synonym: "N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)" EXACT [EC:1.13.12.11] +synonym: "Ziegler's enzyme" RELATED [EC:1.13.12.11] +xref: EC:1.14.13.8 +xref: MetaCyc:1.14.13.8-RXN +xref: Reactome:R-HSA-139970 "FMO3:FAD N-oxidises TMA to TMAO" +xref: Reactome:R-HSA-217255 "FMO1:FAD N-oxidises TAM" +xref: Reactome:R-HSA-5602966 "Defective FMO3 does not N-oxidise TMA" +xref: RHEA:24468 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004500 +name: dopamine beta-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O." [EC:1.14.17.1, RHEA:19117] +synonym: "(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity" EXACT [EC:1.14.17.1] +synonym: "3,4-dihydroxyphenethylamine beta-oxidase activity" EXACT [EC:1.14.17.1] +synonym: "3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)" EXACT [EC:1.14.17.1] +synonym: "4-(2-aminoethyl)pyrocatechol beta-oxidase activity" EXACT [EC:1.14.17.1] +synonym: "dopa beta-hydroxylase activity" EXACT [EC:1.14.17.1] +synonym: "dopamine b-hydroxylase activity" EXACT [] +synonym: "dopamine beta-hydroxylase activity" EXACT [EC:1.14.17.1] +synonym: "dopamine beta-oxidase activity" EXACT [EC:1.14.17.1] +synonym: "dopamine hydroxylase activity" EXACT [EC:1.14.17.1] +synonym: "dopamine-B-hydroxylase activity" EXACT [EC:1.14.17.1] +synonym: "MDBH (membrane-associated dopamine beta-monooxygenase)" RELATED [EC:1.14.17.1] +synonym: "oxygenase, dopamine beta-mono-" EXACT [EC:1.14.17.1] +synonym: "phenylamine beta-hydroxylase activity" EXACT [EC:1.14.17.1] +synonym: "SDBH (soluble dopamine beta-monooxygenase)" RELATED [EC:1.14.17.1] +xref: EC:1.14.17.1 +xref: KEGG_REACTION:R02535 +xref: MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-209891 "Dopamine is oxidised to noradrenaline" +xref: RHEA:19117 +is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004501 +name: ecdysone 20-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O." [EC:1.14.99.22, RHEA:14021] +synonym: "alpha-ecdysone C-20 hydroxylase activity" EXACT [EC:1.14.99.22] +synonym: "ecdysone 20-hydroxylase activity" EXACT [] +synonym: "ecdysone modification" BROAD [] +synonym: "ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)" EXACT [EC:1.14.99.22] +xref: EC:1.14.99.22 +xref: KEGG_REACTION:R02374 +xref: MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN +xref: RHEA:14021 +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0004502 +name: kynurenine 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+)." [EC:1.14.13.9, RHEA:20545] +synonym: "kynurenine 3-hydroxylase activity" EXACT [] +synonym: "kynurenine hydroxylase activity" EXACT [EC:1.14.13.9] +synonym: "L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.9] +synonym: "L-kynurenine-3-hydroxylase activity" EXACT [EC:1.14.13.9] +xref: EC:1.14.13.9 +xref: KEGG_REACTION:R01960 +xref: MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-71200 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O" +xref: RHEA:20545 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004503 +name: monophenol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [EC:1.14.18.1, GOC:bf, GOC:sart, PMID:4965136] +comment: In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children. +synonym: "catecholase" RELATED [EC:1.14.18.1] +synonym: "chlorogenic acid oxidase activity" RELATED [EC:1.14.18.1] +synonym: "chlorogenic oxidase activity" RELATED [EC:1.14.18.1] +synonym: "cresolase activity" RELATED [EC:1.14.18.1] +synonym: "dopa oxidase" RELATED [EC:1.14.18.1] +synonym: "L-tyrosine monooxygenase activity" EXACT [GOC:bf] +synonym: "monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] +synonym: "monophenol monooxidase activity" EXACT [EC:1.14.18.1] +synonym: "monophenol oxidase activity" EXACT [EC:1.14.18.1] +synonym: "monophenol oxygenase" EXACT [PMID:2494997] +synonym: "monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] +synonym: "monophenol,L-dopa:oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] +synonym: "monophenolase activity" EXACT [EC:1.14.18.1] +synonym: "N-acetyl-6-hydroxytryptophan oxidase activity" EXACT [EC:1.14.18.1] +synonym: "o-diphenol oxidase activity" RELATED [EC:1.14.18.1] +synonym: "o-diphenol oxidoreductase" RELATED [EC:1.14.18.1] +synonym: "o-diphenol:O2 oxidoreductase activity" RELATED [EC:1.14.18.1] +synonym: "o-diphenol:oxygen oxidoreductase" RELATED [EC:1.14.18.1] +synonym: "phenol oxidase activity" BROAD [] +synonym: "phenolase activity" BROAD [EC:1.14.18.1] +synonym: "polyaromatic oxidase activity" EXACT [EC:1.14.18.1] +synonym: "polyphenolase activity" EXACT [EC:1.14.18.1] +synonym: "prophenol oxidase activity" RELATED [GOC:sart] +synonym: "prophenoloxidase activity" RELATED [] +synonym: "pyrocatechol oxidase" BROAD [EC:1.14.18.1] +synonym: "tyrosinase activity" EXACT [EC:1.14.18.1] +synonym: "tyrosine-dopa oxidase activity" EXACT [EC:1.14.18.1] +xref: EC:1.14.18.1 +xref: MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN +xref: RHEA:18117 +is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004504 +name: peptidylglycine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O." [EC:1.14.17.3] +synonym: "PAM activity" EXACT [EC:1.14.17.3] +synonym: "PAM-A" RELATED [EC:1.14.17.3] +synonym: "PAM-B" RELATED [EC:1.14.17.3] +synonym: "peptide alpha-amidating enzyme" RELATED [EC:1.14.17.3] +synonym: "peptide alpha-amide synthase activity" EXACT [EC:1.14.17.3] +synonym: "peptide-alpha-amide synthetase activity" EXACT [EC:1.14.17.3] +synonym: "peptidyl alpha-amidating enzyme activity" EXACT [EC:1.14.17.3] +synonym: "peptidylglycine 2-hydroxylase activity" EXACT [] +synonym: "peptidylglycine alpha-amidating monooxygenase activity" EXACT [EC:1.14.17.3] +synonym: "peptidylglycine alpha-hydroxylase activity" EXACT [EC:1.14.17.3] +synonym: "peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.17.3] +synonym: "synthase, peptide alpha-amide" EXACT [EC:1.14.17.3] +xref: EC:1.14.17.3 +xref: MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN +is_a: GO:0016715 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004505 +name: phenylalanine 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin." [EC:1.14.16.1] +synonym: "L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.16.1] +synonym: "PAH activity" EXACT [EC:1.14.16.1] +synonym: "phenylalaninase activity" EXACT [EC:1.14.16.1] +synonym: "phenylalanine 4-hydroxylase activity" EXACT [EC:1.14.16.1] +synonym: "phenylalanine hydroxylase activity" EXACT [] +xref: EC:1.14.16.1 +xref: MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-5649483 "Defective PAH does not hydroxylate L-Phe to L-Tyr" +xref: Reactome:R-HSA-71118 "PAH tetramer hydroxylates L-Phe to L-Tyr" +xref: RHEA:20273 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004506 +name: squalene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+)." [RHEA:25282] +synonym: "squalene 2,3-oxidocyclase activity" EXACT [EC:1.14.14.17] +synonym: "squalene epoxidase activity" EXACT [EC:1.14.14.17] +synonym: "squalene hydroxylase activity" EXACT [EC:1.14.14.17] +synonym: "squalene oxydocyclase activity" EXACT [EC:1.14.14.17] +synonym: "squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity" EXACT [KEGG_REACTION:R02874] +synonym: "squalene-2,3-epoxidase activity" EXACT [EC:1.14.14.17] +synonym: "squalene-2,3-epoxide cyclase activity" EXACT [EC:1.14.14.17] +xref: EC:1.14.14.17 +xref: KEGG_REACTION:R02874 +xref: MetaCyc:SQUALENE-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-191299 "Squalene is oxidized to its epoxide" +xref: RHEA:25282 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004507 +name: steroid 11-beta-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.4] +synonym: "cytochrome P450 CYP11B1" NARROW [] +synonym: "cytochrome P450 CYP11B2" NARROW [] +synonym: "cytochrome p450 XIB1 activity" NARROW [EC:1.14.15.4] +synonym: "oxygenase, steroid 11beta -mono-" EXACT [EC:1.14.15.4] +synonym: "steroid 11-beta-hydroxylase activity" EXACT [] +synonym: "steroid 11-beta/18-hydroxylase activity" EXACT [EC:1.14.15.4] +synonym: "steroid 11beta-hydroxylase activity" EXACT [EC:1.14.15.4] +synonym: "steroid 11beta-monooxygenase activity" EXACT [EC:1.14.15.4] +synonym: "steroid 11beta/18-hydroxylase activity" EXACT [EC:1.14.15.4] +synonym: "steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)" EXACT [EC:1.14.15.4] +xref: EC:1.14.15.4 +xref: MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-193997 "CYP11B1 oxidises 11DCORT" +xref: Reactome:R-HSA-194017 "CYP11B2 oxidises 11DCORST to CORST" +xref: Reactome:R-HSA-5580292 "Defective CYP11B1 does not oxidise 11DCORT" +xref: Reactome:R-HSA-5600598 "Defective CYP11B2 does not oxidise 11DCORST" +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004508 +name: steroid 17-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O." [EC:1.14.14.19] +synonym: "17alpha-hydroxylase-C17,20 lyase activity" EXACT [EC:1.14.14.19] +synonym: "cytochrome P-450 (P-45017alpha,lyase)" RELATED [EC:1.14.14.19] +synonym: "cytochrome P450 CYP17" NARROW [] +synonym: "cytochrome p450 XVIIA1 activity" NARROW [EC:1.14.14.19] +synonym: "cytochrome P45017alpha" RELATED [EC:1.14.14.19] +synonym: "steroid 17-alpha-hydroxylase activity" EXACT [] +synonym: "steroid 17-alpha-hydroxylase-C17-20 lyase activity" EXACT [] +synonym: "steroid 17-alpha-hydroxylase/17,20 lyase activity" EXACT [EC:1.14.14.19] +synonym: "steroid 17alpha-hydroxylase activity" EXACT [EC:1.14.14.19] +synonym: "steroid 17alpha-monooxygenase activity" EXACT [EC:1.14.14.19] +synonym: "steroid 17alphahydroxylase/17,20 lyase activity" EXACT [EC:1.14.14.19] +synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)" EXACT [EC:1.14.14.19] +xref: EC:1.14.14.19 +xref: MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-193068 "CYP17A1 17-hydroxylates PREG" +xref: Reactome:R-HSA-193070 "Side chain cleavage of 17alpha-hydroxypregnenolone to yield DHA" +xref: Reactome:R-HSA-193072 "CYP17A1 17-hydroxylates P4" +xref: Reactome:R-HSA-193099 "CYP17A1 cleaves 17aHPROG to ANDST" +xref: Reactome:R-HSA-5601843 "Defective CYP17A1 does not 17-hydroxylate PREG" +xref: Reactome:R-HSA-9035954 "Defective CYP17A1 does not 17-hydroxylate P4" +xref: Reactome:R-HSA-9035956 "Defective CYP17A1 does not cleave 17aHPROG" +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0004509 +name: steroid 21-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O." [EC:1.14.14.16] +synonym: "21-hydroxylase activity" EXACT [EC:1.14.14.16] +synonym: "cytochrome P450 CYP21A1" NARROW [] +synonym: "cytochrome p450 XXIA1 activity" NARROW [EC:1.14.14.16] +synonym: "steroid 21-hydroxylase activity" EXACT [] +synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)" EXACT [EC:1.14.14.16] +xref: EC:1.14.14.16 +xref: MetaCyc:STEROID-21-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-193964 "CYP21A2 21-hydroxylates PROG" +xref: Reactome:R-HSA-193981 "CYP21A2 oxidises 17HPROG" +xref: Reactome:R-HSA-5601976 "Defective CYP21A2 does not 21-hydroxylate PROG" +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0004510 +name: tryptophan 5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O." [EC:1.14.16.4] +synonym: "indoleacetic acid-5-hydroxylase activity" EXACT [EC:1.14.16.4] +synonym: "L-tryptophan hydroxylase activity" EXACT [] +synonym: "L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.16.4] +synonym: "tryptophan 5-hydroxylase activity" EXACT [EC:1.14.16.4] +synonym: "tryptophan hydroxylase activity" EXACT [EC:1.14.16.4] +xref: EC:1.14.16.4 +xref: MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-209828 "Tryptophan is hydroxylated" +xref: RHEA:16709 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004511 +name: tyrosine 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O." [EC:1.14.16.2] +synonym: "L-tyrosine hydroxylase activity" EXACT [EC:1.14.16.2] +synonym: "L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.16.2] +synonym: "tyrosine 3-hydroxylase activity" EXACT [] +synonym: "tyrosine hydroxylase activity" EXACT [] +xref: EC:1.14.16.2 +xref: MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-209823 "Tyrosine is hydroxylated to dopa" +xref: RHEA:18201 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004512 +name: inositol-3-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form." [EC:5.5.1.4, RHEA:10716] +synonym: "1L-myo-inositol-1-phosphate lyase (isomerizing)" EXACT [EC:5.5.1.4] +synonym: "D-glucose 6-phosphate cycloaldolase activity" EXACT [EC:5.5.1.4] +synonym: "glucocycloaldolase activity" EXACT [EC:5.5.1.4] +synonym: "glucose 6-phosphate cyclase activity" EXACT [EC:5.5.1.4] +synonym: "glucose-6-phosphate inositol monophosphate cycloaldolase activity" EXACT [EC:5.5.1.4] +synonym: "inositol 1-phosphate synthatase activity" EXACT [EC:5.5.1.4] +synonym: "inositol 1-phosphate synthetase activity" EXACT [EC:5.5.1.4] +xref: EC:5.5.1.4 +xref: KEGG_REACTION:R07324 +xref: MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN +xref: Reactome:R-HSA-1855178 "Glc6P is isomerised to I3P by ISYNA1 in the cytosol" +xref: RHEA:10716 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0004513 +name: neolactotetraosylceramide alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide." [EC:2.4.99.10] +synonym: "CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity" EXACT [EC:2.4.99.10] +synonym: "cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity" EXACT [EC:2.4.99.10] +synonym: "SAT-3" RELATED [EC:2.4.99.10] +synonym: "sialyltransferase 3" RELATED [EC:2.4.99.10] +xref: EC:2.4.99.10 +xref: MetaCyc:2.4.99.10-RXN +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0004514 +name: nicotinate-nucleotide diphosphorylase (carboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate." [EC:2.4.2.19, RHEA:12733] +synonym: "NAD pyrophosphorylase activity" EXACT [EC:2.4.2.19] +synonym: "nicotinate mononucleotide pyrophosphorylase (carboxylating)" EXACT [EC:2.4.2.19] +synonym: "nicotinate-nucleotide pyrophosphorylase (carboxylating) activity" EXACT [] +synonym: "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)" EXACT [EC:2.4.2.19] +synonym: "QAPRTase activity" EXACT [EC:2.4.2.19] +synonym: "quinolinate phosphoribosyltransferase (decarboxylating) activity" EXACT [EC:2.4.2.19] +synonym: "quinolinic acid phosphoribosyltransferase activity" EXACT [EC:2.4.2.19] +synonym: "quinolinic phosphoribosyltransferase activity" EXACT [EC:2.4.2.19] +xref: EC:2.4.2.19 +xref: KEGG_REACTION:R03348 +xref: MetaCyc:QUINOPRIBOTRANS-RXN +xref: Reactome:R-HSA-197268 "QPRT transfers PRIB to QUIN to form NAMN" +xref: RHEA:12733 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004515 +name: nicotinate-nucleotide adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+." [EC:2.7.7.18] +synonym: "ATP:nicotinate-nucleotide adenylyltransferase activity" EXACT [] +synonym: "ATP:nicotinate-ribonucleotide adenylyltransferase activity" EXACT [EC:2.7.7.18] +synonym: "deamido-NAD(+) diphosphorylase activity" EXACT [EC:2.7.7.18] +synonym: "deamido-NAD(+) pyrophosphorylase activity" EXACT [EC:2.7.7.18] +synonym: "deamido-NAD+ pyrophosphorylase activity" EXACT [EC:2.7.7.18] +synonym: "deamidonicotinamide adenine dinucleotide pyrophosphorylase activity" EXACT [EC:2.7.7.18] +synonym: "NaMN-ATase activity" EXACT [EC:2.7.7.18] +synonym: "nicotinate mononucleotide adenylyltransferase activity" EXACT [EC:2.7.7.18] +synonym: "nicotinic acid mononucleotide adenylyltransferase" NARROW [] +xref: EC:2.7.7.18 +xref: MetaCyc:NICONUCADENYLYLTRAN-RXN +xref: Reactome:R-HSA-197235 "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD" +xref: Reactome:R-HSA-200474 "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD" +xref: Reactome:R-HSA-200512 "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD" +xref: RHEA:22860 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0004516 +name: nicotinate phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate." [EC:6.3.4.21, RHEA:13393] +synonym: "niacin ribonucleotidase activity" EXACT [EC:6.3.4.21] +synonym: "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:6.3.4.21] +synonym: "nicotinic acid mononucleotide glycohydrolase activity" EXACT [EC:6.3.4.21] +synonym: "nicotinic acid mononucleotide pyrophosphorylase activity" EXACT [EC:6.3.4.21] +synonym: "nicotinic acid phosphoribosyltransferase activity" EXACT [EC:6.3.4.21] +xref: EC:6.3.4.21 +xref: KEGG_REACTION:R01724 +xref: MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN +xref: Reactome:R-HSA-197186 "NAPRT1 dimer transfers PRIB to NCA to form NAMN" +xref: RHEA:13393 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004517 +name: nitric-oxide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+." [EC:1.14.13.39, RHEA:19897] +synonym: "endothelium-derived relaxation factor-forming enzyme activity" RELATED [EC:1.14.13.39] +synonym: "endothelium-derived relaxing factor synthase activity" RELATED [EC:1.14.13.39] +synonym: "L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity" EXACT [EC:1.14.13.39] +synonym: "NADPH-diaphorase activity" EXACT [EC:1.14.13.39] +synonym: "nitric oxide synthase activity" EXACT [] +synonym: "nitric oxide synthetase activity" EXACT [EC:1.14.13.39] +synonym: "nitric-oxide synthetase activity" EXACT [EC:1.14.13.39] +synonym: "NO synthase activity" EXACT [EC:1.14.13.39] +xref: EC:1.14.13.39 +xref: MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN +xref: Reactome:R-HSA-202127 "eNOS synthesizes NO" +xref: Reactome:R-HSA-418436 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)" +xref: RHEA:19897 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0004518 +name: nuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684] +comment: Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_plant +subset: goslim_yeast +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds +relationship: part_of GO:0090305 ! nucleic acid phosphodiester bond hydrolysis + +[Term] +id: GO:0004519 +name: endonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks." [GOC:mah, ISBN:0198547684] +xref: Reactome:R-HSA-5358512 "MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more" +xref: Reactome:R-HSA-5358518 "MLH1:PMS2 makes single strand incision near 1-2 base mismatch" +xref: Reactome:R-HSA-5690990 "5'- incision of DNA by ERCC1:ERCC4 in GG-NER" +xref: Reactome:R-HSA-5693533 "DCLRE1C (ARTEMIS) processes DNA DSB ends" +xref: Reactome:R-HSA-72180 "Cleavage of mRNA at the 3'-end" +is_a: GO:0004518 ! nuclease activity + +[Term] +id: GO:0004520 +name: endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah, ISBN:0198547684] +synonym: "DNA nicking activity" RELATED [GOC:mah] +synonym: "endonuclease G activity" RELATED [] +xref: Reactome:R-HSA-110359 "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site" +xref: Reactome:R-HSA-5686440 "MUS81:EME1,EME2 cleaves D-loop" +xref: Reactome:R-HSA-5686657 "ERCC1:XPF cleaves flaps generated by SSA" +xref: Reactome:R-HSA-5687464 "MRN and RBBP8 resect DNA DSBs in MMEJ" +xref: Reactome:R-HSA-5690988 "3'-incision of DNA by ERCC5 (XPG) in GG-NER" +xref: Reactome:R-HSA-5693584 "Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)" +xref: Reactome:R-HSA-5693608 "Initial resection of double-strand break ends" +xref: Reactome:R-HSA-6782204 "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER" +xref: Reactome:R-HSA-6782224 "3' incision by ERCC5 (XPG) in TC-NER" +xref: Reactome:R-HSA-9023941 "MRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11" +is_a: GO:0004519 ! endonuclease activity +is_a: GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0004521 +name: endoribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:mah, ISBN:0198547684] +synonym: "endonuclease G activity" RELATED [] +xref: Reactome:R-HSA-425923 "IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced" +xref: Reactome:R-HSA-426520 "Endonucleolytic RISC hydrolyzes target RNAs" +xref: Reactome:R-HSA-5601887 "PLD6 dimer cleaves primary piRNA transcript to pre-piRNA" +xref: Reactome:R-HSA-5601910 "Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA" +xref: Reactome:R-HSA-6791223 "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol" +xref: Reactome:R-HSA-6814555 "Integrator complex processes the 3' end of snRNA" +xref: Reactome:R-HSA-9009936 "RNASEL cleaves cellular ssRNA" +xref: Reactome:R-HSA-9009941 "RNASEL cleaves viral ssRNA" +xref: Reactome:R-HSA-9023909 "C3PO hydrolyzes cleaved passenger strand" +xref: Reactome:R-HSA-9023912 "AGO2 cleaves passenger strand of duplex siRNA" +xref: Reactome:R-HSA-927836 "SMG6 hydrolyzes mRNA with premature termination codon" +is_a: GO:0004519 ! endonuclease activity +is_a: GO:0004540 ! ribonuclease activity +relationship: part_of GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic + +[Term] +id: GO:0004522 +name: ribonuclease A activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates." [EC:4.6.1.18] +synonym: "alkaline ribonuclease activity" EXACT [] +synonym: "ceratitis capitata alkaline ribonuclease activity" EXACT [] +synonym: "endoribonuclease I" RELATED [] +synonym: "gene S glycoproteins" RELATED [] +synonym: "gene S locus-specific glycoproteins" RELATED [] +synonym: "pancreatic ribonuclease activity" NARROW [EC:4.6.1.18] +synonym: "pancreatic RNase activity" EXACT [EC:4.6.1.18] +synonym: "ribonuclease I activity" EXACT [EC:4.6.1.18] +synonym: "ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity" EXACT [] +synonym: "ribonucleic phosphatase activity" EXACT [] +synonym: "RNase A activity" EXACT [EC:4.6.1.18] +synonym: "RNase activity" BROAD [EC:4.6.1.18] +synonym: "RNase I activity" EXACT [EC:4.6.1.18] +synonym: "S-genotype-assocd. glycoproteins" RELATED [] +synonym: "SLSG glycoproteins" RELATED [] +xref: EC:4.6.1.18 +xref: MetaCyc:3.1.27.5-RXN +xref: Wikipedia:Ribonuclease_A +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0004523 +name: RNA-DNA hybrid ribonuclease activity +namespace: molecular_function +alt_id: GO:0004524 +def: "Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters." [EC:3.1.26.4] +comment: Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species. +synonym: "calf thymus ribonuclease H activity" EXACT [] +synonym: "endoribonuclease H" RELATED [EC:3.1.26.4] +synonym: "endoribonuclease H (calf thymus)" RELATED [EC:3.1.26.4] +synonym: "endoribonuclease0 H activity" NARROW [EC:3.1.26.4] +synonym: "hybrid nuclease activity" EXACT [EC:3.1.26.4] +synonym: "hybrid ribonuclease activity" EXACT [EC:3.1.26.4] +synonym: "hybridase (ribonuclease H)" EXACT [EC:3.1.26.4] +synonym: "hybridase activity" EXACT [EC:3.1.26.4] +synonym: "ribonuclease H activity" EXACT [GOC:vw] +synonym: "ribonuclease H1 activity" NARROW [] +synonym: "ribonuclease H2 activity" NARROW [] +synonym: "ribonuclease H3 activity" NARROW [] +synonym: "RNA*DNA hybrid ribonucleotidohydrolase activity" EXACT [EC:3.1.26.4] +synonym: "RNase H activity" EXACT [] +synonym: "RNase H1 activity" NARROW [] +synonym: "RNase H2 activity" NARROW [] +synonym: "RNase H3 activity" NARROW [] +xref: EC:3.1.26.4 +xref: MetaCyc:3.1.26.4-RXN +xref: Reactome:R-HSA-164519 "RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex" +xref: Reactome:R-HSA-164528 "RNase H-mediated cleavage of the template strand" +xref: Reactome:R-HSA-173769 "RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers" +xref: Reactome:R-HSA-182795 "RNase H-mediated degradation of the template strand" +xref: Reactome:R-HSA-182859 "RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex" +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0004525 +name: ribonuclease III activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt." [PMID:11157775, PMID:15242644] +synonym: "pre-mRNA 3'-end processing endonuclease" NARROW [] +synonym: "ribonuclease 3 activity" EXACT [EC:3.1.26.3] +synonym: "RNase III activity" EXACT [EC:3.1.26.3] +xref: EC:3.1.26.3 +xref: MetaCyc:3.1.26.3-RXN +xref: Reactome:R-HSA-203862 "Dicer cleaves pre-miRNA to yield duplex miRNA" +xref: Reactome:R-HSA-203893 "Microprocessor complex cleaves pri-miRNA to pre-miRNA" +xref: Reactome:R-HSA-426464 "Dicer cleaves double-stranded RNA to yield double-stranded siRNA" +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters +is_a: GO:0032296 ! double-stranded RNA-specific ribonuclease activity + +[Term] +id: GO:0004526 +name: ribonuclease P activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor." [EC:3.1.26.5] +synonym: "RNase P" EXACT [] +synonym: "tRNA 5' leader endonuclease activity" EXACT [] +xref: EC:3.1.26.5 +xref: MetaCyc:3.1.26.5-RXN +xref: Reactome:R-HSA-5696810 "RNase P cleaves the 5' end of pre-tRNA" +xref: Reactome:R-HSA-6785722 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript" +xref: Reactome:R-HSA-6786854 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript" +xref: Wikipedia:RNase_P +is_a: GO:0004549 ! tRNA-specific ribonuclease activity +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0004527 +name: exonuclease activity +namespace: molecular_function +alt_id: GO:0008857 +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end." [GOC:mah, ISBN:0198547684] +synonym: "exonuclease IX activity" NARROW [] +is_a: GO:0004518 ! nuclease activity + +[Term] +id: GO:0004528 +name: phosphodiesterase I activity +namespace: molecular_function +def: "Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides." [EC:3.1.4.1] +synonym: "5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [EC:3.1.4.1] +synonym: "5'-exonuclease activity" RELATED [EC:3.1.4.1] +synonym: "5'-NPDase activity" RELATED [EC:3.1.4.1] +synonym: "5'-nucleotide phosphodiesterase activity" RELATED [EC:3.1.4.1] +synonym: "5'-PDase activity" RELATED [EC:3.1.4.1] +synonym: "5'-PDE activity" RELATED [EC:3.1.4.1] +synonym: "5'-phosphodiesterase activity" RELATED [EC:3.1.4.1] +synonym: "5'NPDE activity" RELATED [EC:3.1.4.1] +synonym: "alkaline phosphodiesterase activity" RELATED [EC:3.1.4.1] +synonym: "exonuclease I activity" RELATED [EC:3.1.4.1] +synonym: "nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [EC:3.1.4.1] +synonym: "oligonucleate 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.1] +synonym: "orthophosphoric diester phosphohydrolase activity" EXACT [EC:3.1.4.1] +synonym: "PDE I activity" EXACT [EC:3.1.4.1] +synonym: "phosphodiesterase activity" BROAD [EC:3.1.4.1] +xref: EC:3.1.4.1 +xref: MetaCyc:3.1.4.1-RXN +is_a: GO:0004527 ! exonuclease activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0004529 +name: exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule." [GOC:mah, ISBN:0198547684] +is_a: GO:0004527 ! exonuclease activity +is_a: GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0004530 +name: deoxyribonuclease I activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products." [EC:3.1.21.1] +synonym: "alkaline deoxyribonuclease activity" EXACT [EC:3.1.21.1] +synonym: "alkaline DNase activity" EXACT [EC:3.1.21.1] +synonym: "deoxyribonuclease (pancreatic)" NARROW [EC:3.1.21.1] +synonym: "deoxyribonuclease A" RELATED [EC:3.1.21.1] +synonym: "deoxyribonucleic phosphatase activity" EXACT [EC:3.1.21.1] +synonym: "DNA depolymerase activity" EXACT [EC:3.1.21.1] +synonym: "DNA endonuclease activity" EXACT [EC:3.1.21.1] +synonym: "DNA nuclease activity" EXACT [EC:3.1.21.1] +synonym: "DNAase activity" EXACT [EC:3.1.21.1] +synonym: "DNase activity" NARROW [EC:3.1.21.1] +synonym: "DNase I" RELATED [EC:3.1.21.1] +synonym: "dornava" RELATED [EC:3.1.21.1] +synonym: "dornavac" RELATED [EC:3.1.21.1] +synonym: "endodeoxyribonuclease I" RELATED [EC:3.1.21.1] +synonym: "Escherichia coli endonuclease I" RELATED [EC:3.1.21.1] +synonym: "pancreatic deoxyribonuclease" NARROW [EC:3.1.21.1] +synonym: "pancreatic DNase activity" NARROW [EC:3.1.21.1] +synonym: "pancreatic dornase" NARROW [EC:3.1.21.1] +synonym: "thymonuclease activity" NARROW [EC:3.1.21.1] +synonym: "thymonuclease, dornase activity" EXACT [EC:3.1.21.1] +xref: EC:3.1.21.1 +xref: MetaCyc:3.1.21.1-RXN +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0004531 +name: deoxyribonuclease II activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products." [EC:3.1.22.1] +synonym: "acid deoxyribonuclease activity" EXACT [EC:3.1.22.1] +synonym: "acid DNase activity" EXACT [EC:3.1.22.1] +synonym: "deoxyribonucleate 3'-nucleotidohydrolase activity" EXACT [EC:3.1.22.1] +synonym: "DNase II activity" EXACT [EC:3.1.22.1] +synonym: "lysosomal DNase II activity" NARROW [EC:3.1.22.1] +synonym: "pancreatic DNase II" RELATED [EC:3.1.22.1] +xref: EC:3.1.22.1 +xref: MetaCyc:3.1.22.1-RXN +is_a: GO:0016889 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0004532 +name: exoribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] +xref: Reactome:R-HSA-429961 "DCPS scavenges the 7-methylguanosine cap of mRNA" +is_a: GO:0004527 ! exonuclease activity +is_a: GO:0004540 ! ribonuclease activity +relationship: part_of GO:0090503 ! RNA phosphodiester bond hydrolysis, exonucleolytic + +[Term] +id: GO:0004533 +name: exoribonuclease H activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions." [EC:3.1.13.2, ISBN:0198547684] +synonym: "retroviral reverse transcriptase RNaseH" RELATED [EC:3.1.13.2] +xref: EC:3.1.13.2 +xref: MetaCyc:3.1.13.2-RXN +is_a: GO:0016896 ! exoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0004534 +name: 5'-3' exoribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] +xref: EC:3.1.13 +xref: Reactome:R-HSA-429845 "5' to 3' exoribonuclease hydrolyzes decapped mRNA" +is_a: GO:0008409 ! 5'-3' exonuclease activity +is_a: GO:0016896 ! exoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0004535 +name: poly(A)-specific ribonuclease activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP." [EC:3.1.13.4, ISBN:0198547684] +synonym: "2',3'-exoribonuclease activity" RELATED [EC:3.1.13.4] +synonym: "3'-exoribonuclease activity" EXACT [EC:3.1.13.4] +synonym: "poly(A)-specific RNase activity" EXACT [] +xref: EC:3.1.13.4 +xref: MetaCyc:3.1.13.4-RXN +xref: Reactome:R-HSA-429955 "CCR4-NOT complex deadenylates mRNA" +xref: Reactome:R-HSA-429992 "PARN deadenylates mRNA" +xref: Reactome:R-HSA-430021 "PAN2-PAN3 complex partially deadenylates mRNA" +is_a: GO:0000175 ! 3'-5'-exoribonuclease activity + +[Term] +id: GO:0004536 +name: deoxyribonuclease activity +namespace: molecular_function +alt_id: GO:0004537 +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] +synonym: "caspase-activated deoxyribonuclease activity" NARROW [] +xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40" +xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2" +xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)" +is_a: GO:0004518 ! nuclease activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0004540 +name: ribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:mah, ISBN:0198547684] +is_a: GO:0004518 ! nuclease activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +relationship: part_of GO:0090501 ! RNA phosphodiester bond hydrolysis + +[Term] +id: GO:0004549 +name: tRNA-specific ribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules." [GOC:mah] +synonym: "tRNA-specific RNase activity" EXACT [] +xref: Reactome:R-HSA-5696813 "TSEN complex cleaves the intron from pre-tRNA" +xref: Reactome:R-HSA-5696815 "ELAC2 cleaves the 3' end of pre-tRNA" +xref: Reactome:R-HSA-6785722 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript" +xref: Reactome:R-HSA-6786854 "Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript" +is_a: GO:0004540 ! ribonuclease activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0004550 +name: nucleoside diphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate." [EC:2.7.4.6] +synonym: "ATP:nucleoside-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.6] +synonym: "NDK activity" EXACT [EC:2.7.4.6] +synonym: "nucleoside 5'-diphosphate kinase activity" EXACT [EC:2.7.4.6] +synonym: "nucleoside 5'-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.6] +synonym: "nucleoside diphosphate (UDP) kinase activity" EXACT [EC:2.7.4.6] +synonym: "nucleoside diphosphokinase activity" EXACT [EC:2.7.4.6] +synonym: "nucleoside-diphosphate kinase activity" EXACT [] +synonym: "nucleotide phosphate kinase activity" EXACT [EC:2.7.4.6] +synonym: "UDP kinase activity" EXACT [EC:2.7.4.6] +synonym: "uridine diphosphate kinase activity" EXACT [EC:2.7.4.6] +xref: EC:2.7.4.6 +xref: MetaCyc:NUCLEOSIDE-DIP-KIN-RXN +xref: Reactome:R-HSA-2162096 "carbovir diphosphate + ATP => carbovir triphosphate + ADP" +xref: Reactome:R-HSA-482619 "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)" +xref: Reactome:R-HSA-482621 "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)" +xref: Reactome:R-HSA-482804 "(d)NDP + ATP <=> (d)NTP + ADP (NME4)" +xref: Reactome:R-HSA-482812 "(d)NTP + ADP <=> (d)NDP + ATP (NME4)" +xref: Reactome:R-HSA-6806877 "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs" +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity +relationship: part_of GO:0006165 ! nucleoside diphosphate phosphorylation + +[Term] +id: GO:0004551 +name: nucleotide diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides." [EC:3.6.1.9] +synonym: "dinucleotide nucleotidohydrolase activity" EXACT [EC:3.6.1.9] +synonym: "nucleotide pyrophosphatase activity" EXACT [] +synonym: "nucleotide-sugar pyrophosphatase activity" EXACT [EC:3.6.1.9] +xref: EC:3.6.1.9 +xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN +xref: Reactome:R-HSA-196955 "2xENPP1 hydrolyzes FAD to FMN" +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0004552 +name: octanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH." [EC:1.1.1.73, RHEA:24620] +synonym: "1-octanol dehydrogenase activity" EXACT [EC:1.1.1.73] +synonym: "octanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.73] +xref: EC:1.1.1.73 +xref: KEGG_REACTION:R02878 +xref: MetaCyc:OCTANOL-DEHYDROGENASE-RXN +xref: RHEA:24620 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004553 +name: hydrolase activity, hydrolyzing O-glycosyl compounds +namespace: molecular_function +alt_id: GO:0016800 +def: "Catalysis of the hydrolysis of any O-glycosyl bond." [GOC:mah] +synonym: "O-glucosyl hydrolase activity" EXACT [] +xref: EC:3.2.1 +xref: Reactome:R-HSA-5694563 "ABHD10 hydrolyses MPAG" +xref: Reactome:R-HSA-6786652 "CHIT1 hydrolyses CHIT to 3xADGP" +is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds + +[Term] +id: GO:0004555 +name: alpha,alpha-trehalase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose." [EC:3.2.1.28] +synonym: "alpha,alpha-trehalose glucohydrolase activity" EXACT [EC:3.2.1.28] +xref: EC:3.2.1.28 +xref: MetaCyc:TREHALA-RXN +xref: Reactome:R-HSA-188985 "trehalose + H2O => 2 D-glucose" +xref: RHEA:20868 +is_a: GO:0015927 ! trehalase activity + +[Term] +id: GO:0004556 +name: alpha-amylase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units." [EC:3.2.1.1] +synonym: "1,4-alpha-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.1] +synonym: "alpha amylase activity" EXACT [EC:3.2.1.1] +synonym: "endoamylase activity" EXACT [EC:3.2.1.1] +synonym: "glycogenase activity" BROAD [EC:3.2.1.1] +synonym: "taka-amylase A" RELATED [EC:3.2.1.1] +xref: EC:3.2.1.1 +xref: MetaCyc:ALPHA-AMYL-RXN +xref: MetaCyc:RXN-1823 +xref: MetaCyc:RXN-1825 +xref: Reactome:R-HSA-188979 "Digestion of linear starch (amylose) by extracellular amylase" +xref: Reactome:R-HSA-191114 "Digestion of branched starch (amylopectin) by extracellular amylase" +is_a: GO:0016160 ! amylase activity + +[Term] +id: GO:0004557 +name: alpha-galactosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase." [EC:3.2.1.22] +synonym: "alpha-D-galactosidase activity" EXACT [EC:3.2.1.22] +synonym: "alpha-D-galactoside galactohydrolase activity" EXACT [EC:3.2.1.22] +synonym: "alpha-galactosidase A" RELATED [EC:3.2.1.22] +synonym: "alpha-galactoside galactohydrolase activity" EXACT [EC:3.2.1.22] +synonym: "melibiase activity" EXACT [] +xref: EC:3.2.1.22 +xref: MetaCyc:ALPHAGALACTOSID-RXN +xref: Reactome:R-HSA-1605736 "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers" +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0004558 +name: alpha-1,4-glucosidase activity +namespace: molecular_function +alt_id: GO:0004562 +alt_id: GO:0016982 +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose." [EC:3.2.1.20] +synonym: "acid maltase activity" EXACT [EC:3.2.1.20] +synonym: "alpha-1,4-glucosidase activity" EXACT [EC:3.2.1.20] +synonym: "alpha-D-glucosidase activity" EXACT [EC:3.2.1.20] +synonym: "alpha-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.20] +synonym: "alpha-glucopyranosidase activity" EXACT [EC:3.2.1.20] +synonym: "alpha-glucosidase II" RELATED [] +synonym: "alpha-glucoside hydrolase activity" EXACT [EC:3.2.1.20] +synonym: "glucoinvertase activity" EXACT [EC:3.2.1.20] +synonym: "glucosidoinvertase activity" EXACT [EC:3.2.1.20] +synonym: "glucosidosucrase activity" EXACT [EC:3.2.1.20] +synonym: "lysosomal alpha-glucosidase activity" BROAD [EC:3.2.1.20] +synonym: "maltase-glucoamylase activity" EXACT [EC:3.2.1.20] +xref: EC:3.2.1.20 +xref: MetaCyc:MALTODEXGLUCOSID-RXN +xref: Reactome:R-HSA-189053 "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose" +xref: Reactome:R-HSA-189102 "maltose + H2O => 2 D-glucose (maltase-glucoamylase)" +xref: Reactome:R-HSA-191101 "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)" +xref: Reactome:R-HSA-191108 "maltose + H2O => 2 D-glucose (sucrase-isomaltase)" +xref: Reactome:R-HSA-191116 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)" +xref: Reactome:R-HSA-5659861 "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)" +xref: Reactome:R-HSA-5659879 "Defective SI does not hydrolyze iMal" +xref: Reactome:R-HSA-5659899 "Defective SI does not hydrolyze maltotriose" +xref: Reactome:R-HSA-5659922 "Defective SI does not hydrolyze Mal" +is_a: GO:0090599 ! alpha-glucosidase activity + +[Term] +id: GO:0004559 +name: alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides." [EC:3.2.1.24] +synonym: "1,2-alpha-D-mannosidase activity" NARROW [EC:3.2.1.24] +synonym: "1,2-alpha-mannosidase" NARROW [EC:3.2.1.24] +synonym: "alpha-D-mannopyranosidase activity" EXACT [EC:3.2.1.24] +synonym: "alpha-D-mannosidase activity" EXACT [EC:3.2.1.24] +synonym: "alpha-D-mannoside mannohydrolase activity" EXACT [EC:3.2.1.24] +synonym: "exo-alpha-mannosidase activity" EXACT [EC:3.2.1.24] +synonym: "p-nitrophenyl-alpha-mannosidase activity" NARROW [EC:3.2.1.24] +xref: EC:3.2.1.24 +xref: MetaCyc:3.2.1.24-RXN +xref: Reactome:R-HSA-6799545 "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5" +xref: Reactome:R-HSA-8853686 "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3" +is_a: GO:0015923 ! mannosidase activity + +[Term] +id: GO:0004560 +name: alpha-L-fucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose." [EC:3.2.1.51] +synonym: "alpha-fucosidase activity" EXACT [EC:3.2.1.51] +synonym: "alpha-L-fucoside fucohydrolase activity" EXACT [EC:3.2.1.51] +xref: EC:3.2.1.51 +xref: MetaCyc:ALPHA-L-FUCOSIDASE-RXN +xref: Reactome:R-HSA-5693807 "FUCA1 hydrolyses NGP:1,6-GlcNAc" +is_a: GO:0015928 ! fucosidase activity + +[Term] +id: GO:0004561 +name: alpha-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides." [EC:3.2.1.50] +synonym: "alpha-acetylglucosaminidase activity" EXACT [EC:3.2.1.50] +synonym: "alpha-D-2-acetamido-2-deoxyglucosidase activity" EXACT [EC:3.2.1.50] +synonym: "alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity" EXACT [EC:3.2.1.50] +synonym: "N-acetyl-alpha-D-glucosaminidase activity" EXACT [EC:3.2.1.50] +synonym: "N-acetyl-alpha-glucosaminidase activity" EXACT [EC:3.2.1.50] +synonym: "NAG activity" EXACT [EC:3.2.1.50] +xref: EC:3.2.1.50 +xref: MetaCyc:3.2.1.50-RXN +xref: Reactome:R-HSA-1678742 "NAGLU hydrolyses Heparan sulfate chain(4)" +xref: Reactome:R-HSA-2090038 "NAGLU hydrolyses heparan chain(2)" +xref: Reactome:R-HSA-2263496 "Defective NAGLU does not hydrolyse Heparan sulfate chain(4)" +xref: Reactome:R-HSA-9036052 "Defective NAGLU does not hydrolyse heparan chain(2)" +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0004563 +name: beta-N-acetylhexosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides." [EC:3.2.1.52] +synonym: "beta-acetylaminodeoxyhexosidase activity" EXACT [EC:3.2.1.52] +synonym: "beta-acetylhexosaminidinase activity" EXACT [EC:3.2.1.52] +synonym: "beta-D-hexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "beta-D-N-acetylhexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "beta-hexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "beta-N-acetyl-D-hexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity" EXACT [EC:3.2.1.52] +synonym: "hexosaminidase A" RELATED [EC:3.2.1.52] +synonym: "N-acetyl-beta-D-hexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "N-acetyl-beta-glucosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "N-acetyl-beta-hexosaminidase activity" EXACT [EC:3.2.1.52] +synonym: "N-acetylhexosaminidase activity" EXACT [EC:3.2.1.52] +xref: EC:3.2.1.52 +xref: MetaCyc:3.2.1.52-RXN +xref: Reactome:R-HSA-1605595 "Hexosaminidase A cleaves GalNAc from GM2 to form GM3" +xref: Reactome:R-HSA-1605632 "Both hexosaminidase A and B can cleave GalNAc from globoside" +xref: Reactome:R-HSA-1638053 "HEXA cleaves the terminal GalNAc from keratan sulfate" +xref: Reactome:R-HSA-2105001 "HEXA cleaves the terminal GalNAc from DS" +xref: Reactome:R-HSA-2162225 "HEXA cleaves the terminal GalNAc from small HA fragments" +xref: Reactome:R-HSA-3656259 "Defective HEXA does not cleave the terminal GalNAc from DS" +xref: Reactome:R-HSA-3662344 "Defective HEXB does not cleave the terminal GalNAc from DS" +xref: Reactome:R-HSA-9035976 "Defective HEXA does not cleave the terminall GalNAc from small HA fragments" +xref: Reactome:R-HSA-9035978 "Defective HEXA does not cleave the terminal GalNAc from keratan sulfate" +xref: Reactome:R-HSA-9035982 "Defective HEXB does not cleave the terminal GalNAc from HA fragments" +xref: Reactome:R-HSA-9035983 "Defective HEXB does not cleave the terminal GalNAc from keratan sulfate" +xref: Reactome:R-HSA-9638075 "HEXB cleaves the terminal GalNAc from DS" +xref: Reactome:R-HSA-9638076 "HEXB cleaves the terminal GalNAc from small HA fragments" +xref: Reactome:R-HSA-9638078 "HEXB cleaves the terminal GalNAc from keratan sulfate" +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0004564 +name: beta-fructofuranosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside." [EC:3.2.1.26, MetaCyc:RXN-9985] +synonym: "acid invertase activity" BROAD [] +synonym: "alkaline invertase activity" BROAD [] +synonym: "beta-D-fructofuranoside fructohydrolase activity" EXACT [] +synonym: "beta-fructosidase activity" RELATED [] +synonym: "beta-h-fructosidase activity" RELATED [] +synonym: "fructosylinvertase activity" RELATED [] +synonym: "glucosucrase activity" RELATED [] +synonym: "invertase activity" BROAD [] +synonym: "invertin activity" BROAD [] +synonym: "maxinvert L 1000 activity" RELATED [] +synonym: "saccharase activity" RELATED [] +xref: EC:3.2.1.26 +xref: MetaCyc:RXN-9985 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004565 +name: beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides." [EC:3.2.1.23] +comment: Note that the inclusion of 'MetaCyc:BGALACT-PWY' is exceptional: normally MetaCyc pathway entries are database references for biological process terms, not molecular function terms. An exception was made in this case because the MetaCyc entry 'BGALACT-PWY' describes only one reaction, that catalyzed by beta-galactosidase. +synonym: "beta-D-galactanase activity" EXACT [EC:3.2.1.23] +synonym: "beta-D-galactoside galactohydrolase activity" EXACT [EC:3.2.1.23] +synonym: "beta-D-lactosidase activity" EXACT [EC:3.2.1.23] +synonym: "beta-lactosidase activity" EXACT [EC:3.2.1.23] +synonym: "exo-(1->4)-beta-D-galactanase activity" EXACT [EC:3.2.1.23] +synonym: "hydrolact" RELATED [EC:3.2.1.23] +synonym: "lactose hydrolysis" RELATED [] +synonym: "lactozym" RELATED [EC:3.2.1.23] +synonym: "maxilact" RELATED [EC:3.2.1.23] +synonym: "oryzatym" RELATED [EC:3.2.1.23] +synonym: "S 2107" RELATED [EC:3.2.1.23] +synonym: "sumiklat" RELATED [EC:3.2.1.23] +synonym: "trilactase activity" EXACT [EC:3.2.1.23] +xref: EC:3.2.1.23 +xref: MetaCyc:3.2.1.23-RXN +xref: MetaCyc:BGALACT-PWY +xref: Reactome:R-HSA-1605624 "Beta-galactosidase hydrolyses GM1 to GM2" +xref: Reactome:R-HSA-1606312 "Beta-galactosidase can also hydrolyse globosides to form cerebrosides" +xref: Reactome:R-HSA-1630306 "GLB1 hydrolyses a glycosaminoglycan" +xref: Reactome:R-HSA-1793217 "Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase" +xref: Reactome:R-HSA-2090079 "GLB1 hydrolyses linker chain(2)" +xref: Reactome:R-HSA-2265534 "Defective GLB1 does not hydrolyse a glycosaminoglycan" +xref: Reactome:R-HSA-9036061 "Defective GLB1 does not hydrolyse linker chain(2)" +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0004566 +name: beta-glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate." [EC:3.2.1.31] +synonym: "beta-D-glucuronoside glucuronosohydrolase activity" EXACT [EC:3.2.1.31] +synonym: "beta-glucuronide glucuronohydrolase activity" EXACT [EC:3.2.1.31] +synonym: "exo-beta-D-glucuronidase activity" EXACT [EC:3.2.1.31] +synonym: "glucuronidase activity" EXACT [EC:3.2.1.31] +synonym: "ketodase activity" EXACT [EC:3.2.1.31] +xref: EC:3.2.1.31 +xref: MetaCyc:BETA-GLUCURONID-RXN +xref: Reactome:R-HSA-1678854 "GUSB tetramer hydrolyses CS/HS precursor" +xref: Reactome:R-HSA-2162226 "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc" +xref: Reactome:R-HSA-2162227 "GUSB tetramer hydrolyses (HA)2" +xref: Reactome:R-HSA-2318373 "Defective GUSB does not hydrolyse (HA)2" +xref: Reactome:R-HSA-9036068 "Defective GUSB does not hydrolyse GlcA-1,3-GlcNAc" +xref: Reactome:R-HSA-9036070 "Defective GUSB does not hydrolyse CS/HS precursor" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004567 +name: beta-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides." [EC:3.2.1.25] +synonym: "beta-D-mannosidase activity" EXACT [EC:3.2.1.25] +synonym: "beta-D-mannoside mannohydrolase activity" EXACT [EC:3.2.1.25] +synonym: "beta-mannoside mannohydrolase activity" EXACT [EC:3.2.1.25] +synonym: "exo-beta-D-mannanase activity" EXACT [EC:3.2.1.25] +synonym: "mannanase activity" EXACT [EC:3.2.1.25] +synonym: "mannase activity" EXACT [EC:3.2.1.25] +xref: EC:3.2.1.25 +xref: MetaCyc:3.2.1.25-RXN +xref: Reactome:R-HSA-8853710 "MANBA hydrolyses GlcNAc:Man" +is_a: GO:0015923 ! mannosidase activity + +[Term] +id: GO:0004568 +name: chitinase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins." [EC:3.2.1.14, GOC:bf, GOC:kah, GOC:pde, PMID:11468293] +synonym: "1,4-beta-poly-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.14] +synonym: "beta-1,4-poly-N-acetyl glucosamidinase activity" EXACT [EC:3.2.1.14] +synonym: "chitodextrinase activity" EXACT [EC:3.2.1.14] +synonym: "poly-beta-glucosaminidase activity" EXACT [EC:3.2.1.14] +synonym: "poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity" EXACT [EC:3.2.1.14] +xref: EC:3.2.1.14 +xref: MetaCyc:3.2.1.14-RXN +xref: Reactome:R-HSA-6786421 "CHIA hydrolyses chitin" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004569 +name: glycoprotein endo-alpha-1,2-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane." [EC:3.2.1.130] +synonym: "endo-alpha-mannosidase activity" EXACT [EC:3.2.1.130] +synonym: "endomannosidase activity" EXACT [EC:3.2.1.130] +synonym: "glucosyl mannosidase activity" EXACT [EC:3.2.1.130] +synonym: "glucosylmannosidase activity" EXACT [EC:3.2.1.130] +synonym: "glycoprotein glucosylmannohydrolase activity" EXACT [EC:3.2.1.130] +xref: EC:3.2.1.130 +xref: MetaCyc:3.2.1.130-RXN +xref: Reactome:R-HSA-964759 "Alternative endo-mannosidase I route" +is_a: GO:0004559 ! alpha-mannosidase activity + +[Term] +id: GO:0004571 +name: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide." [GOC:bf, PMID:25092655] +synonym: "1,2-alpha-mannosidase" EXACT [EC:3.2.1.113] +synonym: "1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [EC:3.2.1.113] +synonym: "exo-alpha-1,2-mannanase activity" EXACT [EC:3.2.1.113] +synonym: "glycoprotein processing mannosidase I" RELATED [EC:3.2.1.113] +synonym: "Man9-mannosidase activity" NARROW [EC:3.2.1.113] +synonym: "man9-mannosidase activity" NARROW [EC:3.2.1.113] +synonym: "ManI activity" NARROW [EC:3.2.1.113] +synonym: "mannose-9 processing alpha-mannosidase activity" NARROW [EC:3.2.1.113] +synonym: "mannosidase 1A activity" NARROW [EC:3.2.1.113] +synonym: "mannosidase 1B activity" NARROW [EC:3.2.1.113] +synonym: "mannosidase I" RELATED [EC:3.2.1.113] +xref: EC:3.2.1.113 +xref: KEGG_REACTION:R05982 +xref: KEGG_REACTION:R06722 +xref: MetaCyc:3.2.1.113-RXN +xref: Reactome:R-HSA-4793949 "Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch)" +xref: Reactome:R-HSA-6782685 "EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5" +xref: Reactome:R-HSA-901024 "MAN1B1 hydrolyses 1,2-linked mannose (a branch)" +xref: Reactome:R-HSA-901036 "MAN1B1 hydrolyses a second 1,2-linked mannose (a branch)" +xref: Reactome:R-HSA-901039 "MAN1B1 hydrolyses 1,2-linked mannose (c branch)" +xref: Reactome:R-HSA-901074 "MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch)" +xref: Reactome:R-HSA-9036008 "Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch)" +xref: Reactome:R-HSA-9036011 "Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch)" +xref: Reactome:R-HSA-9036012 "Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch)" +xref: Reactome:R-HSA-964737 "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2" +xref: Reactome:R-HSA-964825 "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2" +xref: Reactome:R-HSA-964830 "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2" +is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity + +[Term] +id: GO:0004572 +name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3)." [EC:3.2.1.114] +synonym: "1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [EC:3.2.1.114] +synonym: "alpha-(1,3/6)-mannosidase activity" EXACT [EC:3.2.1.114] +synonym: "alpha-D-mannosidase II" RELATED [EC:3.2.1.114] +synonym: "alpha-mannosidase II" RELATED [EC:3.2.1.114] +synonym: "exo-1,3-1,6-alpha-mannosidase activity" EXACT [EC:3.2.1.114] +synonym: "GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity" EXACT [EC:3.2.1.114] +synonym: "Golgi alpha-mannosidase II" RELATED [EC:3.2.1.114] +synonym: "ManII activity" NARROW [EC:3.2.1.114] +synonym: "mannosidase II activity" NARROW [EC:3.2.1.114] +synonym: "mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity" EXACT [] +synonym: "mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity" EXACT [] +synonym: "mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity" EXACT [] +xref: EC:3.2.1.114 +xref: MetaCyc:3.2.1.114-RXN +xref: Reactome:R-HSA-975814 "Trimming of mannoses on the alpha1,6 arm by MAN2A1" +is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity + +[Term] +id: GO:0004573 +name: mannosyl-oligosaccharide glucosidase activity +namespace: molecular_function +def: "Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2)." [EC:3.2.1.106] +synonym: "Glc3Man9NAc2 oligosaccharide glucosidase activity" EXACT [EC:3.2.1.106] +synonym: "mannosyl-oligosaccharide glucohydrolase activity" EXACT [EC:3.2.1.106] +synonym: "mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity" EXACT [] +synonym: "processing A-glucosidase I activity" RELATED [EC:3.2.1.106] +synonym: "trimming glucosidase I" RELATED [EC:3.2.1.106] +xref: EC:3.2.1.106 +xref: MetaCyc:3.2.1.106-RXN +xref: Reactome:R-HSA-4793947 "Defective MOGS does not cleave glucose from an N-glycosylated protein" +xref: Reactome:R-HSA-532678 "Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase" +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0004574 +name: oligo-1,6-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose." [EC:3.2.1.10] +synonym: "alpha-limit dextrinase activity" EXACT [EC:3.2.1.10] +synonym: "alpha-methylglucosidase activity" RELATED [GOC:rb] +synonym: "dextrin 6-glucanohydrolase activity" EXACT [EC:3.2.1.10] +synonym: "dextrin 6alpha-glucanohydrolase activity" EXACT [EC:3.2.1.10] +synonym: "exo-oligo-1,6-glucosidase activity" EXACT [EC:3.2.1.10] +synonym: "isomaltase activity" RELATED [EC:3.2.1.10] +synonym: "limit dextrinase" RELATED [] +synonym: "oligosaccharide alpha-1,6-glucohydrolase activity" EXACT [EC:3.2.1.10] +synonym: "oligosaccharide alpha-1,6-glucosidase activity" EXACT [EC:3.2.1.10] +synonym: "sucrase-isomaltase activity" RELATED [EC:3.2.1.10] +xref: EC:3.2.1.10 +xref: MetaCyc:3.2.1.10-RXN +is_a: GO:0090599 ! alpha-glucosidase activity + +[Term] +id: GO:0004575 +name: sucrose alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose." [EC:3.2.1.48, MetaCyc:RXN-1461] +synonym: "alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis" BROAD [] +synonym: "beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis" BROAD [] +synonym: "intestinal sucrase activity" RELATED [EC:3.2.1.48] +synonym: "sucrase activity" RELATED [EC:3.2.1.48] +synonym: "sucrase(invertase)" RELATED [EC:3.2.1.48] +synonym: "sucrase-isomaltase activity" RELATED [EC:3.2.1.48] +synonym: "sucrose alpha-D-glucohydrolase activity" EXACT [] +synonym: "sucrose alpha-glucohydrolase activity" EXACT [EC:3.2.1.48] +synonym: "sucrose hydrolysis" BROAD [] +synonym: "sucrose-alpha-D-glucohydrolase activity" EXACT [EC:3.2.1.48] +xref: EC:3.2.1.48 +xref: KEGG_REACTION:R00802 +xref: MetaCyc:RXN-1461 +xref: Reactome:R-HSA-189069 "sucrose + H2O => glucose + fructose" +xref: Reactome:R-HSA-5659926 "Defective SI does not hydrolyze Suc" +is_a: GO:0004564 ! beta-fructofuranosidase activity +is_a: GO:0090599 ! alpha-glucosidase activity + +[Term] +id: GO:0004576 +name: oligosaccharyl transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] +synonym: "oligosaccharide transferase activity" EXACT [GOC:mah] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0004577 +name: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol." [EC:2.4.1.141] +synonym: "N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity" EXACT [EC:2.4.1.141] +synonym: "UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity" EXACT [EC:2.4.1.141] +synonym: "UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.141] +synonym: "uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.141] +xref: EC:2.4.1.141 +xref: MetaCyc:2.4.1.141-RXN +xref: Reactome:R-HSA-446207 "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP" +xref: Reactome:R-HSA-5633241 "Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP" +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0004578 +name: chitobiosyldiphosphodolichol beta-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol." [EC:2.4.1.142] +synonym: "GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity" EXACT [EC:2.4.1.142] +synonym: "GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.142] +synonym: "guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity" EXACT [EC:2.4.1.142] +xref: EC:2.4.1.142 +xref: MetaCyc:2.4.1.142-RXN +xref: Reactome:R-HSA-446218 "Addition of the first mannose to the N-glycan precursor by ALG1" +xref: Reactome:R-HSA-4549382 "Defective ALG1 does not transfer the first Man to the N-glycan precursor" +is_a: GO:0019187 ! beta-1,4-mannosyltransferase activity + +[Term] +id: GO:0004579 +name: dolichyl-diphosphooligosaccharide-protein glycotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine." [RHEA:22980] +synonym: "asparagine N-glycosyltransferase activity" EXACT [] +synonym: "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity" EXACT [] +synonym: "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity" EXACT [] +synonym: "dolichyldiphosphooligosaccharide-protein glycosyltransferase activity" EXACT [] +synonym: "dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity" EXACT [] +synonym: "dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity" EXACT [] +synonym: "dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity" EXACT [] +synonym: "oligomannosyltransferase activity" RELATED [] +xref: EC:2.4.99.18 +xref: MetaCyc:2.4.1.119-RXN +xref: Reactome:R-HSA-446209 "Transfer of N-glycan to the protein" +xref: RHEA:22980 +is_a: GO:0004576 ! oligosaccharyl transferase activity + +[Term] +id: GO:0004581 +name: dolichyl-phosphate beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate." [EC:2.4.1.117] +synonym: "polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose dolichyl-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose:dolichol phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose:dolicholphosphoryl glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose:dolichyl monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose:dolichyl phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.117] +synonym: "uridine diphosphoglucose-dolichol glucosyltransferase activity" EXACT [EC:2.4.1.117] +xref: EC:2.4.1.117 +xref: MetaCyc:2.4.1.117-RXN +xref: Reactome:R-HSA-446214 "Synthesis of dolichyl-phosphate-glucose" +xref: RHEA:15401 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0004582 +name: dolichyl-phosphate beta-D-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate." [EC:2.4.1.83] +synonym: "dolichol phosphate mannose synthase activity" EXACT [EC:2.4.1.83] +synonym: "dolichol-phosphate mannose synthase activity" EXACT [EC:2.4.1.83] +synonym: "dolichol-phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "dolichol-phosphate-mannose synthase activity" EXACT [] +synonym: "dolichyl mannosyl phosphate synthase activity" EXACT [EC:2.4.1.83] +synonym: "dolichyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "dolichyl-phosphate mannose synthase activity" EXACT [EC:2.4.1.83] +synonym: "dolichyl-phospho-mannose synthase activity" EXACT [EC:2.4.1.83] +synonym: "DPM synthase activity" EXACT [] +synonym: "GDP-mannose-dolichol phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "GDPMan:DolP mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "GDPmannose-dolichylmonophosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "GDPmannose:dolichyl-phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] +synonym: "mannosylphosphodolichol synthase activity" EXACT [EC:2.4.1.83] +synonym: "mannosylphosphoryldolichol synthase activity" EXACT [EC:2.4.1.83] +xref: EC:2.4.1.83 +xref: MetaCyc:2.4.1.83-RXN +xref: Reactome:R-HSA-162721 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose" +xref: Reactome:R-HSA-4717406 "Defective DPM1 does not transfer mannose to DOLP to form DOLPman" +xref: Reactome:R-HSA-4719354 "Defective DPM3 does not transfer mannose to DOLP to form DOLPman" +xref: Reactome:R-HSA-4719375 "Defective DPM2 does not transfer mannose to DOLP to form DOLPman" +xref: RHEA:21184 +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0004583 +name: dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide." [GOC:mah] +xref: MetaCyc:RXN-5472 +xref: Reactome:R-HSA-446189 "Addition of a second glucose to the N-glycan precursor by ALG8" +xref: Reactome:R-HSA-446194 "Addition of a third glucose to the N-glycan precursor by an ALG10 homologue" +xref: Reactome:R-HSA-446202 "Addition of the first glucose to the N-glycan precursor by ALG6" +xref: Reactome:R-HSA-4724291 "Defective ALG6 does not add glucose to the N-glycan precursor" +xref: Reactome:R-HSA-4724330 "Defective ALG8 does not add glucose to the N-glycan precursor" +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0004584 +name: obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide." [EC:2.4.1.130] +comment: The reason for obsoletion is that this activity has been replaced by 4 activities in EC, EC:2.4.1.258, EC:2.4.1.259, EC:2.4.1.260, and EC:2.4.1.261. +synonym: "dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.130] +synonym: "dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.130] +synonym: "oligomannosylsynthase activity" BROAD [EC:2.4.1.130] +xref: EC:2.4.1.130 +xref: MetaCyc:2.4.1.130-RXN +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16022 xsd:anyURI +is_obsolete: true +consider: GO:0052917 +consider: GO:0052918 +consider: GO:0052925 +consider: GO:0052926 + +[Term] +id: GO:0004585 +name: ornithine carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline." [EC:2.1.3.3] +synonym: "carbamoyl-phosphate:L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.3] +synonym: "carbamylphosphate-ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] +synonym: "citrulline phosphorylase activity" EXACT [EC:2.1.3.3] +synonym: "L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.3] +synonym: "L-ornithine carbamyltransferase activity" EXACT [EC:2.1.3.3] +synonym: "L-ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] +synonym: "ornithine carbamyltransferase activity" EXACT [EC:2.1.3.3] +synonym: "ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] +synonym: "OTC activity" EXACT [EC:2.1.3.3] +synonym: "OTCase activity" EXACT [EC:2.1.3.3] +xref: EC:2.1.3.3 +xref: MetaCyc:ORNCARBAMTRANSFER-RXN +xref: MetaCyc:RXN-13482 +xref: Reactome:R-HSA-70560 "carbamoyl phosphate + ornithine => citrulline + orthophosphate" +xref: RHEA:19513 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity +relationship: part_of GO:0006591 ! ornithine metabolic process + +[Term] +id: GO:0004586 +name: ornithine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine." [EC:4.1.1.17, RHEA:22964] +synonym: "L-ornithine carboxy-lyase (putrescine-forming)" EXACT [EC:4.1.1.17] +synonym: "L-ornithine carboxy-lyase activity" NARROW [EC:4.1.1.17] +synonym: "SpeC" RELATED [EC:4.1.1.17] +xref: EC:4.1.1.17 +xref: KEGG_REACTION:R00670 +xref: MetaCyc:ORNDECARBOX-RXN +xref: Reactome:R-HSA-70692 "ornithine => putrescine + CO2" +xref: RHEA:22964 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004587 +name: ornithine-oxo-acid transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid." [EC:2.6.1.13] +synonym: "GabT" RELATED [EC:2.6.1.13] +synonym: "L-ornithine 5-aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "L-ornithine aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "L-ornithine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "L-ornithine:alpha-ketoglutarate delta-aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "OAT" RELATED [EC:2.6.1.13] +synonym: "ornithine 5-aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine delta-transaminase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine ketoacid aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine transaminase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--2-oxoacid aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--keto acid aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--keto acid transaminase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--oxo acid aminotransferase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine--oxo-acid transaminase activity" EXACT [EC:2.6.1.13] +synonym: "ornithine-oxo-acid aminotransferase activity" EXACT [] +synonym: "ornithine:alpha-oxoglutarate transaminase activity" EXACT [EC:2.6.1.13] +xref: EC:2.6.1.13 +xref: MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-70654 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]" +xref: Reactome:R-HSA-70666 "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]" +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004588 +name: orotate phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.10] +synonym: "OPRT activity" EXACT [EC:2.4.2.10] +synonym: "OPRTase activity" EXACT [EC:2.4.2.10] +synonym: "orotate phosphoribosyl pyrophosphate transferase activity" EXACT [EC:2.4.2.10] +synonym: "orotic acid phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine 5'-monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine-5'-phosphate diphosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine-5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylate phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylate pyrophosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylic acid phosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylic acid pyrophosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylic phosphorylase activity" EXACT [EC:2.4.2.10] +synonym: "orotidylic pyrophosphorylase activity" EXACT [EC:2.4.2.10] +xref: EC:2.4.2.10 +xref: MetaCyc:OROPRIBTRANS-RXN +xref: Reactome:R-HSA-73567 "orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate" +xref: RHEA:10380 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004589 +name: orotate reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate." [EC:1.3.1.14, RHEA:13513] +synonym: "(S)-dihydroorotate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.14] +xref: EC:1.3.1.14 +xref: KEGG_REACTION:R01869 +xref: MetaCyc:OROTATE-REDUCTASE-NADH-RXN +xref: RHEA:13513 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004590 +name: orotidine-5'-phosphate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP." [EC:4.1.1.23, RHEA:11596] +synonym: "ODCase activity" EXACT [EC:4.1.1.23] +synonym: "OMP decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "OMP-DC" RELATED [EC:4.1.1.23] +synonym: "OMPdcase activity" EXACT [EC:4.1.1.23] +synonym: "orotate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotate monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotic decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidine 5'-phosphate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidine monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidine phosphate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidine-5'-monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidine-5'-phosphate carboxy-lyase (UMP-forming)" EXACT [EC:4.1.1.23] +synonym: "orotidine-5'-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.23] +synonym: "orotidylic acid decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotidylic decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "orotodylate decarboxylase activity" EXACT [EC:4.1.1.23] +synonym: "UMP synthase activity" EXACT [EC:4.1.1.23] +synonym: "uridine 5'-monophosphate synthase activity" EXACT [EC:4.1.1.23] +xref: EC:4.1.1.23 +xref: KEGG_REACTION:R00965 +xref: MetaCyc:OROTPDECARB-RXN +xref: Reactome:R-HSA-73564 "orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2" +xref: RHEA:11596 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004591 +name: oxoglutarate dehydrogenase (succinyl-transferring) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2." [EC:1.2.4.2] +synonym: "2-ketoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "2-oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "2-oxoglutarate: lipoate oxidoreductase activity" EXACT [EC:1.2.4.2] +synonym: "2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)" EXACT [EC:1.2.4.2] +synonym: "2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity" EXACT [EC:1.2.4.2] +synonym: "AKGDH activity" EXACT [EC:1.2.4.2] +synonym: "alpha-ketoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "alpha-ketoglutaric acid dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "alpha-ketoglutaric dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "alpha-oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "ketoglutaric dehydrogenase activity" EXACT [EC:1.2.4.2] +synonym: "OGDC activity" EXACT [EC:1.2.4.2] +synonym: "oxoglutarate decarboxylase activity" EXACT [EC:1.2.4.2] +synonym: "oxoglutarate dehydrogenase (lipoamide) activity" EXACT [] +synonym: "oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] +xref: EC:1.2.4.2 +xref: MetaCyc:2OXOGLUTDECARB-RXN +is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor + +[Term] +id: GO:0004592 +name: pantoate-beta-alanine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate." [EC:6.3.2.1] +synonym: "(R)-pantoate:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.1] +synonym: "D-pantoate:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.1] +synonym: "pantoate-activating enzyme activity" RELATED [EC:6.3.2.1] +synonym: "pantoic-activating enzyme activity" RELATED [EC:6.3.2.1] +synonym: "pantothenate synthetase activity" EXACT [EC:6.3.2.1] +xref: EC:6.3.2.1 +xref: MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN +xref: RHEA:10912 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0004593 +name: pantothenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine." [EC:3.5.1.22, RHEA:12448] +synonym: "(R)-pantothenate amidohydrolase activity" EXACT [EC:3.5.1.22] +synonym: "pantothenate amidohydrolase activity" EXACT [EC:3.5.1.22] +synonym: "pantothenate hydrolase activity" EXACT [EC:3.5.1.22] +xref: EC:3.5.1.22 +xref: KEGG_REACTION:R02474 +xref: MetaCyc:PANTOTHENASE-RXN +xref: RHEA:12448 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0004594 +name: pantothenate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate." [EC:2.7.1.33] +synonym: "ATP:(R)-pantothenate 4'-phosphotransferase activity" EXACT [EC:2.7.1.33] +synonym: "ATP:pantothenate 4'-phosphotransferase activity" EXACT [EC:2.7.1.33] +synonym: "D-pantothenate kinase activity" EXACT [EC:2.7.1.33] +synonym: "pantothenate kinase (phosphorylating) activity" EXACT [EC:2.7.1.33] +synonym: "pantothenic acid kinase activity" EXACT [EC:2.7.1.33] +xref: EC:2.7.1.33 +xref: MetaCyc:PANTOTHENATE-KIN-RXN +xref: Reactome:R-HSA-196857 "PANK2 phosphorylates PanK" +xref: Reactome:R-HSA-199203 "PANK1/3/4 phosphorylate PanK" +xref: RHEA:16373 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004595 +name: pantetheine-phosphate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate." [EC:2.7.7.3, RHEA:19801] +synonym: "3'-dephospho-CoA pyrophosphorylase activity" EXACT [EC:2.7.7.3] +synonym: "ATP:pantetheine-4'-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.3] +synonym: "ATP:pantetheine-phosphate adenylyltransferase activity" EXACT [] +synonym: "dephospho-CoA diphosphorylase activity" EXACT [EC:2.7.7.3] +synonym: "dephospho-CoA pyrophosphorylase activity" EXACT [EC:2.7.7.3] +synonym: "dephospho-coenzyme A pyrophosphorylase activity" EXACT [EC:2.7.7.3] +synonym: "pantetheine phosphate adenylyltransferase activity" EXACT [EC:2.7.7.3] +synonym: "phosphopantetheine adenylyltransferase activity" EXACT [] +synonym: "PPAT activity" EXACT [EC:2.7.7.3] +xref: EC:2.7.7.3 +xref: KEGG_REACTION:R03035 +xref: MetaCyc:PANTEPADENYLYLTRAN-RXN +xref: Reactome:R-HSA-196754 "COASY transfers an adenylyl group from ATP to PPANT" +xref: RHEA:19801 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0004596 +name: peptide alpha-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein." [GOC:mah, PMID:30054468] +synonym: "acetyl-CoA:peptide alpha-N-acetyltransferase activity" EXACT [] +synonym: "acetyl-CoA:peptide nalpha-acetyltransferase activity" EXACT [] +synonym: "amino-terminal amino acid-acetylating enzyme activity" RELATED [] +synonym: "beta-endorphin acetyltransferase activity" NARROW [] +synonym: "N(alpha)-acetyltransferase activity" RELATED [] +synonym: "nalpha-acetyltransferase activity" EXACT [] +synonym: "NAT activity" RELATED [] +synonym: "peptide acetyltransferase activity" RELATED [] +synonym: "protein N-terminal acetyltransferase activity" EXACT [] +xref: MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-6814090 "NatC acetylates ARFFRP1" +is_a: GO:0034212 ! peptide N-acetyltransferase activity + +[Term] +id: GO:0004597 +name: peptide-aspartate beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2." [EC:1.14.11.16] +synonym: "aspartate beta-hydroxylase activity" EXACT [EC:1.14.11.16] +synonym: "aspartyl/asparaginyl beta-hydroxylase activity" RELATED [EC:1.14.11.16] +synonym: "aspartylpeptide beta-dioxygenase activity" EXACT [EC:1.14.11.16] +synonym: "peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.16] +xref: EC:1.14.11.16 +xref: MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004598 +name: peptidylamidoglycolate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate." [EC:4.3.2.5] +synonym: "alpha-hydroxyglycine amidating dealkylase activity" EXACT [EC:4.3.2.5] +synonym: "HGAD" RELATED [EC:4.3.2.5] +synonym: "PAL" RELATED [EC:4.3.2.5] +synonym: "peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity" EXACT [EC:4.3.2.5] +synonym: "peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)" EXACT [EC:4.3.2.5] +synonym: "peptidylamidoglycolate peptidylamide-lyase activity" EXACT [EC:4.3.2.5] +synonym: "PGL" RELATED [EC:4.3.2.5] +xref: EC:4.3.2.5 +xref: MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN +is_a: GO:0016842 ! amidine-lyase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004600 +name: obsolete cyclophilin +namespace: molecular_function +def: "OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity." [EC:5.2.1.8, ISBN:0198506732] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "cyclophilin" EXACT [] +is_obsolete: true +consider: GO:0003755 +consider: GO:0016018 + +[Term] +id: GO:0004601 +name: peroxidase activity +namespace: molecular_function +alt_id: GO:0016685 +alt_id: GO:0016686 +alt_id: GO:0016687 +alt_id: GO:0016693 +def: "Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O." [EC:1.11.1.7, RHEA:56136] +subset: goslim_metagenomics +synonym: "bacterial catalase-peroxidase activity" NARROW [] +synonym: "donor:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.7] +synonym: "eosinophil peroxidase activity" NARROW [] +synonym: "extensin peroxidase" NARROW [EC:1.11.1.7] +synonym: "guaiacol peroxidase" NARROW [EC:1.11.1.7] +synonym: "heme peroxidase" NARROW [EC:1.11.1.7] +synonym: "horseradish peroxidase (HRP)" NARROW [EC:1.11.1.7] +synonym: "japanese radish peroxidase" NARROW [EC:1.11.1.7] +synonym: "lactoperoxidase activity" NARROW [] +synonym: "MPO" RELATED [EC:1.11.1.7] +synonym: "myeloperoxidase activity" NARROW [] +synonym: "oxyperoxidase activity" EXACT [EC:1.11.1.7] +synonym: "peroxidase reaction" EXACT [] +synonym: "protoheme peroxidase" NARROW [EC:1.11.1.7] +synonym: "pyrocatechol peroxidase" NARROW [EC:1.11.1.7] +synonym: "scopoletin peroxidase" NARROW [EC:1.11.1.7] +synonym: "secretory plant peroxidase activity" NARROW [] +synonym: "thiocyanate peroxidase" NARROW [EC:1.11.1.7] +synonym: "verdoperoxidase" NARROW [EC:1.11.1.7] +xref: EC:1.11.1.7 +xref: KEGG_REACTION:R03532 +xref: MetaCyc:PEROXID-RXN +xref: Reactome:R-HSA-1222346 "AhpC reduces H2O2" +xref: Reactome:R-HSA-140359 "PGG2 is reduced to PGH2 by PTGS1" +xref: Reactome:R-HSA-209815 "Tyrosine is monoiodinated" +xref: Reactome:R-HSA-209840 "Two DITs combine to form thyroxine" +xref: Reactome:R-HSA-209925 "DIT and MIT combine to form triiodothyronine" +xref: Reactome:R-HSA-209973 "Tyrosine is diiodinated" +xref: Reactome:R-HSA-2309773 "PGG2 is reduced to PGH2 by PTGS2" +xref: Reactome:R-HSA-2559639 "Collagen type IV sulfilimine cross-linking by peroxidasin" +xref: Reactome:R-HSA-3341296 "GPX7,8 catalyze peroxidation of P4HB (PDI)" +xref: Reactome:R-HSA-350901 "Iodide is organified" +xref: Reactome:R-HSA-5631885 "PRDX1 overoxidizes" +xref: Reactome:R-HSA-6789031 "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)" +xref: Reactome:R-HSA-6789126 "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)" +xref: Reactome:R-HSA-8855490 "Lactoperoxidase (LPO) produces OSCN-" +xref: Reactome:R-HSA-8933635 "Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide" +xref: RHEA:56136 +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor + +[Term] +id: GO:0004602 +name: glutathione peroxidase activity +namespace: molecular_function +alt_id: GO:0016224 +def: "Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O." [EC:1.11.1.9] +synonym: "glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.9] +synonym: "GSH peroxidase activity" EXACT [EC:1.11.1.9] +synonym: "non-selenium glutathione peroxidase activity" NARROW [] +synonym: "reduced glutathione peroxidase activity" EXACT [EC:1.11.1.9] +synonym: "selenium-glutathione peroxidase activity" EXACT [EC:1.11.1.9] +xref: EC:1.11.1.9 +xref: MetaCyc:GLUTATHIONE-PEROXIDASE-RXN +xref: Reactome:R-HSA-2161791 "15S-HpETE is reduced to 15S-HETE by GPX1/2/4" +xref: Reactome:R-HSA-2161946 "5S-HpETE is reduced to 5S-HETE by GPX1/2/4" +xref: Reactome:R-HSA-2161959 "12R-HpETE is reduced to 12R-HETE by GPX1/2/4" +xref: Reactome:R-HSA-2161999 "12S-HpETE is reduced to 12S-HETE by GPX1/2/4" +xref: Reactome:R-HSA-3323013 "GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O" +xref: Reactome:R-HSA-3341277 "GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O" +xref: Reactome:R-HSA-3341397 "GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O" +xref: Reactome:R-HSA-3343700 "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O" +xref: Reactome:R-HSA-6799695 "GPX5,6 reduce H2O2 to H2O" +xref: Reactome:R-HSA-71676 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O" +xref: RHEA:16833 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0004603 +name: phenylethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine." [EC:2.1.1.28] +synonym: "noradrenalin N-methyltransferase activity" EXACT [EC:2.1.1.28] +synonym: "noradrenaline N-methyltransferase activity" RELATED [EC:2.1.1.28] +synonym: "norepinephrine methyltransferase activity" EXACT [EC:2.1.1.28] +synonym: "norepinephrine N-methyltransferase activity" EXACT [EC:2.1.1.28] +synonym: "phenethanolamine methyltransferase activity" EXACT [EC:2.1.1.28] +synonym: "phenethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.28] +synonym: "S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.28] +xref: EC:2.1.1.28 +xref: MetaCyc:2.1.1.28-RXN +xref: Reactome:R-HSA-209903 "Noradrenaline is converted to adrenaline" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004604 +name: phosphoadenylyl-sulfate reductase (thioredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS." [EC:1.8.4.8, RHEA:11724] +synonym: "3'-phosphoadenylylsulfate reductase activity" EXACT [EC:1.8.4.8] +synonym: "adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.8] +synonym: "adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.8] +synonym: "PAdoPS reductase activity" EXACT [EC:1.8.4.8] +synonym: "PAPS reductase activity" EXACT [EC:1.8.4.8] +synonym: "PAPS reductase, thioredoxin-dependent activity" EXACT [EC:1.8.4.8] +synonym: "PAPS sulfotransferase activity" EXACT [EC:1.8.4.8] +synonym: "phosphoadenosine-phosphosulfate reductase activity" EXACT [EC:1.8.4.8] +synonym: "phosphoadenylyl-sulphate reductase (thioredoxin) activity" EXACT [] +synonym: "thioredoxin:3'-phospho-adenylylsulfate reductase activity" EXACT [EC:1.8.4.8] +synonym: "thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity" EXACT [EC:1.8.4.8] +xref: EC:1.8.4.8 +xref: KEGG_REACTION:R02021 +xref: MetaCyc:1.8.4.8-RXN +xref: RHEA:11724 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0004605 +name: phosphatidate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol." [EC:2.7.7.41] +synonym: "CDP diglyceride pyrophosphorylase activity" EXACT [EC:2.7.7.41] +synonym: "CDP-DG" RELATED [EC:2.7.7.41] +synonym: "CDP-diacylglyceride synthetase activity" EXACT [EC:2.7.7.41] +synonym: "CDP-diacylglycerol synthase activity" EXACT [] +synonym: "CDP-diglyceride diphosphorylase activity" EXACT [] +synonym: "CDP-diglyceride pyrophosphorylase activity" EXACT [] +synonym: "CDP-diglyceride synthase activity" EXACT [] +synonym: "CDP-diglyceride synthetase activity" EXACT [EC:2.7.7.41] +synonym: "CTP-diacylglycerol synthetase activity" EXACT [EC:2.7.7.41] +synonym: "CTP:1,2-diacylglycerophosphate-cytidyl transferase activity" EXACT [EC:2.7.7.41] +synonym: "CTP:phosphatidate cytidylyltransferase activity" EXACT [EC:2.7.7.41] +synonym: "cytidine diphosphoglyceride pyrophosphorylase activity" EXACT [EC:2.7.7.41] +synonym: "DAG synthetase activity" EXACT [EC:2.7.7.41] +synonym: "phosphatidate cytidyltransferase activity" EXACT [EC:2.7.7.41] +synonym: "phosphatidic acid cytidylyltransferase activity" EXACT [EC:2.7.7.41] +xref: EC:2.7.7.41 +xref: MetaCyc:CDPDIGLYSYN-RXN +xref: Reactome:R-HSA-1483121 "PA is converted to CDP-DAG by CDS1" +xref: Reactome:R-HSA-1483165 "PA is converted to CDP-DAG by CDS2" +xref: RHEA:16229 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0004607 +name: phosphatidylcholine-sterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine." [EC:2.3.1.43] +synonym: "LCAT (lecithin-cholesterol acyltransferase)" RELATED [EC:2.3.1.43] +synonym: "LCAT activity" EXACT [EC:2.3.1.43] +synonym: "lecithin--cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] +synonym: "lecithin:cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] +synonym: "phosphatidylcholine:sterol O-acyltransferase activity" EXACT [EC:2.3.1.43] +synonym: "phospholipid--cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] +xref: EC:2.3.1.43 +xref: MetaCyc:2.3.1.43-RXN +xref: Reactome:R-HSA-264695 "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)" +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0004608 +name: phosphatidylethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine." [EC:2.1.1.17, RHEA:11164] +synonym: "lipid methyl transferase activity" EXACT [EC:2.1.1.17] +synonym: "LMTase activity" EXACT [EC:2.1.1.17] +synonym: "PEMT" RELATED [EC:2.1.1.17] +synonym: "phosphatidylethanolamine methyltransferase activity" EXACT [EC:2.1.1.17] +synonym: "phosphatidylethanolamine-N-methylase activity" EXACT [EC:2.1.1.17] +synonym: "phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity" EXACT [EC:2.1.1.17] +synonym: "S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.17] +xref: EC:2.1.1.17 +xref: KEGG_REACTION:R02056 +xref: MetaCyc:2.1.1.17-RXN +xref: Reactome:R-HSA-1483174 "PE is methylated to PC by PEMT" +xref: RHEA:11164 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004609 +name: phosphatidylserine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine." [EC:4.1.1.65, RHEA:20828] +synonym: "phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)" EXACT [EC:4.1.1.65] +synonym: "phosphatidyl-L-serine carboxy-lyase activity" EXACT [EC:4.1.1.65] +synonym: "PS decarboxylase activity" EXACT [EC:4.1.1.65] +xref: EC:4.1.1.65 +xref: KEGG_REACTION:R02055 +xref: MetaCyc:PHOSPHASERDECARB-RXN +xref: Reactome:R-HSA-1483212 "PS is decarboxylated to PE by PISD" +xref: RHEA:20828 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004610 +name: phosphoacetylglucosamine mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate." [EC:5.4.2.3, RHEA:23804] +synonym: "acetylaminodeoxyglucose phosphomutase activity" EXACT [EC:5.4.2.3] +synonym: "acetylglucosamine phosphomutase activity" EXACT [EC:5.4.2.3] +synonym: "N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.3] +synonym: "N-acetyl-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.3] +synonym: "N-acetylglucosamine-phosphate mutase activity" EXACT [EC:5.4.2.3] +synonym: "phospho-N-acetylglucosamine mutase activity" EXACT [EC:5.4.2.3] +xref: EC:5.4.2.3 +xref: KEGG_REACTION:R08193 +xref: MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN +xref: Reactome:R-HSA-446185 "Isomerization of GlcNAc6P to GlcNAc1P" +xref: RHEA:23804 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0004611 +name: phosphoenolpyruvate carboxykinase activity +namespace: molecular_function +def: "Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products." [EC:4.1.1.32] +synonym: "PEP carboxykinase activity" EXACT [EC:4.1.1.32] +synonym: "PEPCK activity" EXACT [EC:4.1.1.32] +synonym: "phosphopyruvate carboxylase activity" EXACT [EC:4.1.1.32] +xref: EC:4.1.1.32 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004612 +name: phosphoenolpyruvate carboxykinase (ATP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate." [EC:4.1.1.49, RHEA:18617] +synonym: "ATP:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.49] +synonym: "ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.49] +synonym: "PEPCK (ATP)" RELATED [EC:4.1.1.49] +synonym: "PEPK" RELATED [EC:4.1.1.49] +synonym: "phosphoenolpyruvate carboxylase (ATP)" EXACT [EC:4.1.1.49] +synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.49] +synonym: "phosphopyruvate carboxykinase" BROAD [EC:4.1.1.49] +synonym: "phosphopyruvate carboxykinase (adenosine triphosphate)" EXACT [EC:4.1.1.49] +synonym: "phosphopyruvate carboxylase (ATP)" EXACT [EC:4.1.1.49] +xref: EC:4.1.1.49 +xref: KEGG_REACTION:R00341 +xref: MetaCyc:PEPCARBOXYKIN-RXN +xref: RHEA:18617 +is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity + +[Term] +id: GO:0004613 +name: phosphoenolpyruvate carboxykinase (GTP) activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2." [EC:4.1.1.32] +synonym: "GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.32] +synonym: "GTP:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.32] +synonym: "phosphoenolpyruvate carboxylase (GTP)" EXACT [] +synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.32] +synonym: "phosphoenolpyruvic carboxykinase (GTP)" EXACT [EC:4.1.1.32] +synonym: "phosphoenolpyruvic carboxylase (GTP)" EXACT [EC:4.1.1.32] +synonym: "phosphopyruvate (guanosine triphosphate) carboxykinase activity" EXACT [EC:4.1.1.32] +synonym: "phosphopyruvate carboxylase (GTP)" EXACT [EC:4.1.1.32] +xref: EC:4.1.1.32 +xref: MetaCyc:4.1.1.32-RXN +xref: Reactome:R-HSA-372819 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]" +xref: Reactome:R-HSA-70241 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol]" +xref: RHEA:10388 +is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity + +[Term] +id: GO:0004614 +name: phosphoglucomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate." [EC:5.4.2.2] +synonym: "alpha-D-glucose 1,6-phosphomutase activity" EXACT [EC:5.4.2.2] +synonym: "glucose phosphomutase activity" EXACT [EC:5.4.2.2] +synonym: "phosphoglucose mutase activity" EXACT [EC:5.4.2.2] +xref: EC:5.4.2.2 +xref: MetaCyc:PHOSPHOGLUCMUT-RXN +xref: Reactome:R-HSA-5609939 "Defective PGM1 does not isomerise G6P to G1P" +xref: Reactome:R-HSA-70272 "PGM:Mg2+ isomerise G6P to G1P" +xref: Reactome:R-HSA-70427 "PGM:Mg2+ isomerise G1P to G6P" +xref: Reactome:R-HSA-9638125 "PGM1:Mg2+ isomerises G1P to G6P" +xref: Reactome:R-HSA-9638127 "PGM1:Mg2+ isomerises G6P to G1P" +xref: RHEA:23536 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0004615 +name: phosphomannomutase activity +namespace: molecular_function +alt_id: GO:0008971 +def: "Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate." [EC:5.4.2.8, RHEA:11140] +synonym: "alpha-D-mannose 1,6-phosphomutase activity" EXACT [EC:5.4.2.8] +synonym: "D-mannose 1,6-phosphomutase activity" EXACT [EC:5.4.2.8] +synonym: "mannose phosphomutase activity" EXACT [EC:5.4.2.8] +synonym: "phosphomannose mutase activity" EXACT [EC:5.4.2.8] +xref: EC:5.4.2.8 +xref: KEGG_REACTION:R01818 +xref: MetaCyc:PHOSMANMUT-RXN +xref: Reactome:R-HSA-3781926 "Defective PMM2 does not isomerise Man6P to Man1P" +xref: Reactome:R-HSA-446201 "PMM1,2 isomerise Man6P to Man1P" +xref: RHEA:11140 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0004616 +name: phosphogluconate dehydrogenase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+." [EC:1.1.1.44] +synonym: "6-phospho-D-gluconate dehydrogenase activity" EXACT [EC:1.1.1.44] +synonym: "6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.44] +synonym: "6-phosphogluconate dehydrogenase (decarboxylating)" EXACT [EC:1.1.1.44] +synonym: "6-phosphogluconic carboxylase activity" EXACT [EC:1.1.1.44] +synonym: "6-phosphogluconic dehydrogenase activity" BROAD [EC:1.1.1.44] +synonym: "6PGD activity" EXACT [EC:1.1.1.44] +synonym: "phosphogluconic acid dehydrogenase activity" EXACT [EC:1.1.1.44] +xref: EC:1.1.1.44 +xref: MetaCyc:6PGLUCONDEHYDROG-RXN +xref: Reactome:R-HSA-71299 "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+" +xref: RHEA:10116 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004617 +name: phosphoglycerate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+." [EC:1.1.1.95] +synonym: "3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.95] +synonym: "3-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "3-phosphoglycerate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.95] +synonym: "3-phosphoglyceric acid dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "3PHP reductase activity" EXACT [EC:1.1.1.95] +synonym: "alpha-KG reductase activity" EXACT [EC:1.1.1.95] +synonym: "alpha-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "alphaKG reductase activity" EXACT [EC:1.1.1.95] +synonym: "D- and L-HGA" RELATED [EC:1.1.1.95] +synonym: "D-3-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "D-3-phosphoglycerate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.95] +synonym: "glycerate 3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "glycerate-1,3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "PGDH activity" EXACT [EC:1.1.1.95] +synonym: "phosphoglycerate oxidoreductase activity" EXACT [EC:1.1.1.95] +synonym: "phosphoglyceric acid dehydrogenase activity" EXACT [EC:1.1.1.95] +synonym: "SerA" RELATED [EC:1.1.1.95] +synonym: "SerA 3PG dehydrogenase activity" EXACT [EC:1.1.1.95] +xref: EC:1.1.1.95 +xref: MetaCyc:PGLYCDEHYDROG-RXN +xref: Reactome:R-HSA-977348 "3-phosphoglycerate is dehydrogenated" +xref: RHEA:12641 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004618 +name: phosphoglycerate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+)." [EC:2.7.2.3, RHEA:14801] +synonym: "3-PGK" RELATED [EC:2.7.2.3] +synonym: "3-phosphoglycerate kinase activity" EXACT [EC:2.7.2.3] +synonym: "3-phosphoglycerate phosphokinase activity" EXACT [EC:2.7.2.3] +synonym: "3-phosphoglyceric acid kinase activity" EXACT [EC:2.7.2.3] +synonym: "3-phosphoglyceric acid phosphokinase activity" EXACT [EC:2.7.2.3] +synonym: "3-phosphoglyceric kinase activity" EXACT [EC:2.7.2.3] +synonym: "ATP-3-phospho-D-glycerate-1-phosphotransferase activity" EXACT [EC:2.7.2.3] +synonym: "ATP:3-phospho-D-glycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.3] +synonym: "ATP:D-3-phosphoglycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.3] +synonym: "glycerate 3-phosphate kinase activity" EXACT [EC:2.7.2.3] +synonym: "glycerophosphate kinase activity" EXACT [EC:2.7.2.3] +synonym: "PGK" RELATED [EC:2.7.2.3] +synonym: "phosphoglyceric acid kinase activity" EXACT [EC:2.7.2.3] +synonym: "phosphoglyceric kinase activity" EXACT [EC:2.7.2.3] +synonym: "phosphoglycerokinase activity" EXACT [EC:2.7.2.3] +xref: EC:2.7.2.3 +xref: KEGG_REACTION:R01512 +xref: MetaCyc:PHOSGLYPHOS-RXN +xref: Reactome:R-HSA-70486 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate" +xref: Reactome:R-HSA-71850 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP" +xref: RHEA:14801 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0004619 +name: phosphoglycerate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate." [EC:5.4.2.1] +synonym: "bisphosphoglyceromutase" RELATED [EC:5.4.2.1] +synonym: "D-phosphoglycerate 2,3-phosphomutase activity" EXACT [EC:5.4.2.1] +synonym: "diphosphoglycomutase" RELATED [EC:5.4.2.1] +synonym: "GriP mutase" NARROW [EC:5.4.2.1] +synonym: "monophosphoglycerate mutase activity" EXACT [EC:5.4.2.1] +synonym: "monophosphoglyceromutase activity" EXACT [EC:5.4.2.1] +synonym: "MPGM" RELATED [EC:5.4.2.1] +synonym: "PGA mutase activity" EXACT [EC:5.4.2.1] +synonym: "PGAM activity" EXACT [EC:5.4.2.1] +synonym: "PGM" EXACT [] +synonym: "phosphoglycerate phosphomutase activity" EXACT [EC:5.4.2.1] +synonym: "phosphoglyceromutase activity" EXACT [EC:5.4.2.1] +xref: EC:5.4.2.1 +xref: MetaCyc:3PGAREARR-RXN +xref: Reactome:R-HSA-71445 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate" +xref: Reactome:R-HSA-71654 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate" +xref: RHEA:15901 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0004620 +name: phospholipase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a glycerophospholipid." [ISBN:0198506732] +subset: goslim_chembl +xref: EC:3.1.1 +xref: Reactome:R-HSA-6786650 "DDHD1,2 hydrolyse PA" +xref: Reactome:R-HSA-6792445 "LIPH, I hydrolyse PA to 2-acyl LPA" +is_a: GO:0016298 ! lipase activity + +[Term] +id: GO:0004621 +name: glycosylphosphatidylinositol phospholipase D activity +namespace: molecular_function +def: "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol." [EC:3.1.4.50] +synonym: "glycoprotein phospholipase D activity" EXACT [] +synonym: "glycoprotein-phosphatidylinositol phosphatidohydrolase activity" EXACT [EC:3.1.4.50] +synonym: "GPI-PLD activity" EXACT [EC:3.1.4.50] +synonym: "phosphatidylinositol phospholipase D activity" EXACT [EC:3.1.4.50] +synonym: "phosphatidylinositol-glycan-specific phospholipase D activity" EXACT [EC:3.1.4.50] +synonym: "phosphatidylinositol-specific phospholipase D activity" EXACT [EC:3.1.4.50] +xref: EC:3.1.4.50 +xref: MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN +xref: Reactome:R-HSA-8940388 "GPLD1 hydrolyses GPI-anchors from proteins" +xref: RHEA:10832 +is_a: GO:0004630 ! phospholipase D activity + +[Term] +id: GO:0004622 +name: lysophospholipase activity +namespace: molecular_function +alt_id: GO:0045126 +def: "Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate." [EC:3.1.1.5] +subset: goslim_chembl +synonym: "2-lysophosphatidylcholine acylhydrolase activity" EXACT [EC:3.1.1.5] +synonym: "lecithinase B activity" EXACT [EC:3.1.1.5] +synonym: "lecitholipase activity" EXACT [EC:3.1.1.5] +synonym: "lysolecithinase activity" EXACT [EC:3.1.1.5] +synonym: "lysophopholipase L2" RELATED [EC:3.1.1.5] +synonym: "lysophosphatidase activity" EXACT [EC:3.1.1.5] +synonym: "lysophosphatidylcholine hydrolase activity" EXACT [EC:3.1.1.5] +synonym: "lysophospholipase A1" RELATED [EC:3.1.1.5] +synonym: "phosphatidase B" RELATED [EC:3.1.1.5] +synonym: "phospholipase B activity" EXACT [EC:3.1.1.5] +xref: EC:3.1.1.5 +xref: MetaCyc:LYSOPHOSPHOLIPASE-RXN +xref: Reactome:R-HSA-1482545 "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C" +xref: Reactome:R-HSA-1482571 "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C" +xref: Reactome:R-HSA-1482612 "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]" +xref: Reactome:R-HSA-1482629 "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C" +xref: Reactome:R-HSA-1482685 "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]" +xref: Reactome:R-HSA-1482696 "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C" +xref: Reactome:R-HSA-6814254 "PNPLA6 hydrolyzes LysoPtdCho" +xref: Reactome:R-HSA-6814766 "GDPD1 hydrolyzes LysoPtdCho" +xref: Reactome:R-HSA-6814778 "GDPD3 hydrolyzes LysoPtdCho" +xref: Reactome:R-HSA-8847912 "PNPLA7 hydrolyzes LysoPtdCho" +xref: RHEA:15177 +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004623 +name: phospholipase A2 activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate." [EC:3.1.1.4] +subset: goslim_chembl +synonym: "cytosolic phospholipase A2 activity" NARROW [] +synonym: "lecithinase A activity" EXACT [EC:3.1.1.4] +synonym: "phosphatidase activity" RELATED [EC:3.1.1.4] +synonym: "phosphatidolipase activity" EXACT [EC:3.1.1.4] +synonym: "phosphatidylcholine 2-acylhydrolase activity" EXACT [EC:3.1.1.4] +synonym: "phospholipase A" RELATED [EC:3.1.1.4] +synonym: "secreted phospholipase A2 activity" NARROW [] +xref: EC:3.1.1.4 +xref: MetaCyc:PHOSPHOLIPASE-A2-RXN +xref: Reactome:R-HSA-1482604 "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)" +xref: Reactome:R-HSA-1482656 "PA is hydrolysed to 1-acyl LPA by PLA2[1]" +xref: Reactome:R-HSA-1482679 "PA is hydrolysed to 1-acyl LPA by PLA2G2A" +xref: Reactome:R-HSA-1482745 "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)" +xref: Reactome:R-HSA-1482759 "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)" +xref: Reactome:R-HSA-1482771 "PS is hydrolyzed to 1-acyl LPS by PLA2[9]" +xref: Reactome:R-HSA-1482776 "PS is hydrolyzed to 1-acyl LPS by PLA2G2A" +xref: Reactome:R-HSA-1482778 "CL is hydrolyzed to MLCL by PLA2G6 (IM)" +xref: Reactome:R-HSA-1482816 "PC is hydrolyzed to 1-acyl LPC by PLA2[6]" +xref: Reactome:R-HSA-1482825 "PI is hydrolyzed to 1-acyl LPI by PLA2[11]" +xref: Reactome:R-HSA-1482856 "PC is hydrolyzed to 1-acyl LPC by PLA2[5]" +xref: Reactome:R-HSA-1482868 "PI is hydrolyzed to 1-acyl LPI by PLA2[12]" +xref: Reactome:R-HSA-1482884 "PE is hydrolyzed to 1-acyl LPE by PLA2[2]" +xref: Reactome:R-HSA-1482887 "PE is hydrolyzed to 1-acyl LPE by PLA2[3]" +xref: Reactome:R-HSA-1482897 "PS is hydrolyzed to 2-acyl LPS by PLA2[10]" +xref: Reactome:R-HSA-1482900 "PG is hydrolyzed to 1-acyl LPG by PLA2[1]" +xref: Reactome:R-HSA-1482907 "PG is hydrolyzed to 1-acyl LPG by PLA2G2A" +xref: Reactome:R-HSA-1602368 "PG is hydrolyzed to 1-acyl LPG by PLA2[16]" +xref: Reactome:R-HSA-1602374 "PS is hydrolyzed to 1-acyl LPS by PLA2[15]" +xref: Reactome:R-HSA-1602377 "PI is hydrolyzed to 1-acyl LPI by PLA2[15]" +xref: Reactome:R-HSA-1602398 "PE is hydrolyzed to 1-acyl LPE by PLA2[16]" +xref: Reactome:R-HSA-1602399 "PC is hydrolyzed to 1-acyl LPC by PLB1" +xref: Reactome:R-HSA-1602417 "PC is hydrolyzed to 1-acyl LPC by PLA2[16]" +xref: Reactome:R-HSA-1602446 "PA is hydrolyzed to 1-acyl LPA by PLA2[15]" +xref: Reactome:R-HSA-8848484 "PLA2s hydrolyze phospholipids at the Golgi membrane" +xref: RHEA:15801 +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004624 +name: obsolete secreted phospholipase A2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.4] +comment: This term was made obsolete because it represents component and function information. +synonym: "secreted phospholipase A2 activity" EXACT [] +is_obsolete: true +consider: GO:0004623 +consider: GO:0005576 + +[Term] +id: GO:0004625 +name: obsolete calcium-dependent secreted phospholipase A2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.4] +comment: This term was made obsolete because it represents component and function information. +synonym: "calcium-dependent secreted phospholipase A2 activity" EXACT [] +is_obsolete: true +consider: GO:0005576 +consider: GO:0047498 + +[Term] +id: GO:0004626 +name: obsolete cytosolic phospholipase A2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.4] +comment: This term was made obsolete because it represents component and function information. +synonym: "cytosolic phospholipase A2 activity" EXACT [] +is_obsolete: true +consider: GO:0004623 +consider: GO:0005829 + +[Term] +id: GO:0004627 +name: obsolete calcium-dependent cytosolic phospholipase A2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.4] +comment: This term was made obsolete because it represents component and function information. +synonym: "calcium-dependent cytosolic phospholipase A2 activity" EXACT [] +is_obsolete: true +consider: GO:0005829 +consider: GO:0047498 + +[Term] +id: GO:0004628 +name: obsolete calcium-independent cytosolic phospholipase A2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.4] +comment: This term was made obsolete because it represents component and function information. +synonym: "calcium-independent cytosolic phospholipase A2 activity" EXACT [] +is_obsolete: true +consider: GO:0005829 +consider: GO:0047499 + +[Term] +id: GO:0004629 +name: phospholipase C activity +namespace: molecular_function +alt_id: GO:0042298 +def: "Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate." [EC:3.1.4.3, GOC:mah] +synonym: "lecithinase C activity" RELATED [EC:3.1.4.3] +synonym: "lipophosphodiesterase C" RELATED [EC:3.1.4.3] +synonym: "phosphatidase C" RELATED [EC:3.1.4.3] +xref: EC:3.1.4.3 +xref: MetaCyc:PHOSPHOLIPASE-C-RXN +xref: Reactome:R-HSA-1112666 "BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate" +xref: Reactome:R-HSA-114688 "PLC-beta hydrolyses PIP2 to DAG and IP3" +xref: Reactome:R-HSA-114689 "PLC gamma 2-mediated PIP2 hydrolysis" +xref: Reactome:R-HSA-398193 "PLC beta-mediated PIP2 hydrolysis" +xref: Reactome:R-HSA-399998 "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate" +xref: Reactome:R-HSA-5362553 "NOTUM releases Hh-Np:GPC5 from the plasma membrane" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0004630 +name: phospholipase D activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate." [EC:3.1.4.4] +subset: goslim_chembl +synonym: "choline phosphatase activity" EXACT [EC:3.1.4.4] +synonym: "lecithinase D activity" EXACT [EC:3.1.4.4] +synonym: "lipophosphodiesterase II activity" EXACT [EC:3.1.4.4] +synonym: "phosphatidylcholine phosphatidohydrolase activity" EXACT [EC:3.1.4.4] +xref: EC:3.1.4.4 +xref: MetaCyc:PHOSCHOL-RXN +xref: Reactome:R-HSA-1483142 "PC is transphosphatidylated to PG by PLD1-4/6" +xref: Reactome:R-HSA-1483182 "PC is hydrolyzed to PA and choline by PLD1/2" +xref: Reactome:R-HSA-2029471 "Hydrolysis of PC to PA by PLD" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0004631 +name: phosphomevalonate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+)." [EC:2.7.4.2, RHEA:16341] +synonym: "5-phosphomevalonate kinase activity" EXACT [EC:2.7.4.2] +synonym: "ATP:(R)-5-phosphomevalonate phosphotransferase activity" EXACT [EC:2.7.4.2] +synonym: "ATP:5-phosphomevalonate phosphotransferase activity" EXACT [EC:2.7.4.2] +synonym: "mevalonate phosphate kinase activity" EXACT [EC:2.7.4.2] +synonym: "mevalonate-5-phosphate kinase activity" EXACT [EC:2.7.4.2] +synonym: "mevalonic acid phosphate kinase activity" EXACT [EC:2.7.4.2] +xref: EC:2.7.4.2 +xref: KEGG_REACTION:R03245 +xref: MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN +xref: Reactome:R-HSA-191422 "Mevalonate-5-phosphate is further phosphorylated." +xref: RHEA:16341 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0004632 +name: phosphopantothenate--cysteine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives." [EC:6.3.2.5] +synonym: "(R)-4'-phosphopantothenate:L-cysteine ligase activity" EXACT [EC:6.3.2.5] +synonym: "phosphopantothenate-cysteine ligase activity" EXACT [] +synonym: "phosphopantothenoylcysteine synthetase activity" EXACT [] +xref: EC:6.3.2.5 +xref: MetaCyc:P-PANTOCYSLIG-RXN +xref: Reactome:R-HSA-196753 "2xPPCS ligates PPanK with Cys" +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0004633 +name: phosphopantothenoylcysteine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate." [EC:4.1.1.36, RHEA:16793] +synonym: "4-phosphopantothenoyl-L-cysteine decarboxylase activity" EXACT [EC:4.1.1.36] +synonym: "4-phosphopantotheoylcysteine decarboxylase activity" EXACT [EC:4.1.1.36] +synonym: "N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.36] +synonym: "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)" EXACT [EC:4.1.1.36] +synonym: "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.36] +synonym: "PPC-decarboxylase activity" EXACT [EC:4.1.1.36] +xref: EC:4.1.1.36 +xref: KEGG_REACTION:R03269 +xref: MetaCyc:P-PANTOCYSDECARB-RXN +xref: Reactome:R-HSA-196840 "3xPPCDC:3FMN decarboxylates PPC" +xref: RHEA:16793 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004634 +name: phosphopyruvate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O." [EC:4.2.1.11, ISBN:0198506732] +synonym: "14-3-2-protein" RELATED [EC:4.2.1.11] +synonym: "2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)" EXACT [EC:4.2.1.11] +synonym: "2-phospho-D-glycerate hydro-lyase activity" EXACT [EC:4.2.1.11] +synonym: "2-phospho-D-glycerate-hydrolase activity" EXACT [] +synonym: "2-phosphoglycerate dehydratase activity" EXACT [EC:4.2.1.11] +synonym: "2-phosphoglycerate enolase activity" EXACT [EC:4.2.1.11] +synonym: "2-phosphoglyceric dehydratase activity" EXACT [EC:4.2.1.11] +synonym: "enolase activity" EXACT [EC:4.2.1.11] +synonym: "gamma-enolase activity" EXACT [EC:4.2.1.11] +synonym: "nervous-system specific enolase" NARROW [EC:4.2.1.11] +synonym: "phosphoenolpyruvate hydratase activity" EXACT [EC:4.2.1.11] +xref: EC:4.2.1.11 +xref: MetaCyc:2PGADEHYDRAT-RXN +xref: Reactome:R-HSA-70494 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate" +xref: Reactome:R-HSA-71660 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O" +xref: RHEA:10164 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004635 +name: phosphoribosyl-AMP cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide." [EC:3.5.4.19, RHEA:20049] +synonym: "1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity" EXACT [EC:3.5.4.19] +synonym: "phosphoribosyladenosine monophosphate cyclohydrolase activity" EXACT [EC:3.5.4.19] +synonym: "PRAMP-cyclohydrolase activity" EXACT [EC:3.5.4.19] +xref: EC:3.5.4.19 +xref: KEGG_REACTION:R04037 +xref: MetaCyc:HISTCYCLOHYD-RXN +xref: RHEA:20049 +is_a: GO:0019238 ! cyclohydrolase activity + +[Term] +id: GO:0004636 +name: phosphoribosyl-ATP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+)." [EC:3.6.1.31, RHEA:22828] +synonym: "1-(5-phosphoribosyl)-ATP diphosphohydrolase activity" EXACT [EC:3.6.1.31] +synonym: "phosphoribosyl-ATP pyrophosphatase activity" EXACT [] +synonym: "phosphoribosyladenosine triphosphate pyrophosphatase activity" EXACT [EC:3.6.1.31] +xref: EC:3.6.1.31 +xref: KEGG_REACTION:R04035 +xref: MetaCyc:HISTPRATPHYD-RXN +xref: RHEA:22828 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0004637 +name: phosphoribosylamine-glycine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate." [EC:6.3.4.13, RHEA:17453] +synonym: "2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity" EXACT [EC:6.3.4.13] +synonym: "5'-phosphoribosylglycinamide synthetase activity" EXACT [EC:6.3.4.13] +synonym: "5-phospho-D-ribosylamine:glycine ligase (ADP-forming)" EXACT [EC:6.3.4.13] +synonym: "GAR" RELATED [EC:6.3.4.13] +synonym: "GAR synthetase activity" EXACT [EC:6.3.4.13] +synonym: "GARS activity" EXACT [EC:6.3.4.13] +synonym: "glycinamide ribonucleotide synthetase activity" EXACT [EC:6.3.4.13] +synonym: "glycineamide ribonucleotide synthetase activity" EXACT [EC:6.3.4.13] +synonym: "phosphoribosylglycinamide synthetase activity" EXACT [EC:6.3.4.13] +synonym: "phosphoribosylglycineamide synthetase activity" EXACT [EC:6.3.4.13] +xref: EC:6.3.4.13 +xref: KEGG_REACTION:R04144 +xref: MetaCyc:GLYRIBONUCSYN-RXN +xref: Reactome:R-HSA-73814 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi" +xref: RHEA:17453 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004638 +name: phosphoribosylaminoimidazole carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)." [EC:4.1.1.21, RHEA:10792] +synonym: "1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21] +synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]" RELATED [EC:4.1.1.21] +synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21] +synonym: "5-amino-1-ribosylimidazole 5-phosphate carboxylase activity" EXACT [EC:4.1.1.21] +synonym: "5-phosphoribosyl-5-aminoimidazole carboxylase activity" EXACT [EC:4.1.1.21] +synonym: "ADE2" RELATED [EC:4.1.1.21] +synonym: "AIR carboxylase activity" EXACT [EC:4.1.1.21] +synonym: "class II PurE" RELATED [EC:4.1.1.21] +xref: EC:4.1.1.21 +xref: KEGG_REACTION:R04209 +xref: MetaCyc:AIRCARBOXY-RXN +xref: Reactome:R-HSA-73806 "AIR + CO2 => CAIR" +xref: RHEA:10792 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004639 +name: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate." [EC:6.3.2.6, RHEA:22628] +synonym: "4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] +synonym: "4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity" EXACT [EC:6.3.2.6] +synonym: "4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] +synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)" EXACT [EC:6.3.2.6] +synonym: "5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] +synonym: "phosphoribosylaminoimidazole-succinocarboxamide synthase activity" EXACT [EC:6.3.2.6] +synonym: "phosphoribosylaminoimidazole-succinocarboxamide synthetase activity" EXACT [EC:6.3.2.6] +synonym: "phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity" EXACT [EC:6.3.2.6] +synonym: "PurC" RELATED [EC:6.3.2.6] +synonym: "SAICAR synthase activity" EXACT [EC:6.3.2.6] +synonym: "SAICAR synthetase activity" EXACT [EC:6.3.2.6] +synonym: "SAICARs activity" EXACT [EC:6.3.2.6] +xref: EC:6.3.2.6 +xref: KEGG_REACTION:R04591 +xref: MetaCyc:SAICARSYN-RXN +xref: Reactome:R-HSA-73805 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi" +xref: RHEA:22628 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0004640 +name: phosphoribosylanthranilate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate." [EC:5.3.1.24, RHEA:21540] +synonym: "IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)" RELATED [EC:5.3.1.24] +synonym: "N-(5'-phosphoribosyl)anthranilate isomerase activity" EXACT [EC:5.3.1.24] +synonym: "N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.24] +synonym: "N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity" EXACT [EC:5.3.1.24] +synonym: "PRA isomerase activity" EXACT [EC:5.3.1.24] +synonym: "PRAI activity" EXACT [EC:5.3.1.24] +xref: EC:5.3.1.24 +xref: KEGG_REACTION:R03509 +xref: MetaCyc:PRAISOM-RXN +xref: RHEA:21540 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004641 +name: phosphoribosylformylglycinamidine cyclo-ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate." [EC:6.3.3.1, RHEA:23032] +synonym: "2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.1] +synonym: "2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.1] +synonym: "5'-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.3.1] +synonym: "AIR synthase activity" EXACT [EC:6.3.3.1] +synonym: "AIR synthetase activity" EXACT [EC:6.3.3.1] +synonym: "AIRS activity" EXACT [EC:6.3.3.1] +synonym: "phosphoribosyl-aminoimidazole synthetase activity" EXACT [EC:6.3.3.1] +synonym: "phosphoribosylaminoimidazole synthetase activity" EXACT [EC:6.3.3.1] +xref: EC:6.3.3.1 +xref: KEGG_REACTION:R04208 +xref: MetaCyc:AIRS-RXN +xref: Reactome:R-HSA-73810 "FGAM + ATP => AIR + ADP + Pi" +xref: RHEA:23032 +is_a: GO:0016882 ! cyclo-ligase activity + +[Term] +id: GO:0004642 +name: phosphoribosylformylglycinamidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate." [EC:6.3.5.3, RHEA:17129] +synonym: "2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] +synonym: "5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] +synonym: "FGAM synthase activity" EXACT [EC:6.3.5.3] +synonym: "FGAM synthetase activity" EXACT [EC:6.3.5.3] +synonym: "FGAR amidotransferase activity" EXACT [EC:6.3.5.3] +synonym: "FGARAT activity" EXACT [EC:6.3.5.3] +synonym: "formylglycinamide ribonucloetide amidotransferase activity" EXACT [EC:6.3.5.3] +synonym: "formylglycinamide ribotide amidotransferase activity" EXACT [EC:6.3.5.3] +synonym: "N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] +synonym: "phosphoribosylformylglycinamidine synthetase activity" EXACT [EC:6.3.5.3] +synonym: "phosphoribosylformylglycineamidine synthetase activity" EXACT [EC:6.3.5.3] +xref: EC:6.3.5.3 +xref: KEGG_REACTION:R04463 +xref: MetaCyc:FGAMSYN-RXN +xref: Reactome:R-HSA-73812 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi" +xref: RHEA:17129 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0004643 +name: phosphoribosylaminoimidazolecarboxamide formyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide." [EC:2.1.2.3] +synonym: "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity" EXACT [EC:2.1.2.3] +synonym: "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity" EXACT [EC:2.1.2.3] +synonym: "5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity" EXACT [EC:2.1.2.3] +synonym: "5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity" EXACT [EC:2.1.2.3] +synonym: "5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.3] +synonym: "5-amino-4-imidazolecarboxamide ribotide transformylase activity" EXACT [EC:2.1.2.3] +synonym: "AICAR formyltransferase activity" EXACT [EC:2.1.2.3] +synonym: "AICAR transformylase activity" EXACT [EC:2.1.2.3] +synonym: "aminoimidazolecarboxamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.3] +xref: EC:2.1.2.3 +xref: MetaCyc:AICARTRANSFORM-RXN +xref: Reactome:R-HSA-73798 "AICAR + 10-Formyl-THF => FAICAR + THF" +xref: RHEA:22192 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0004644 +name: phosphoribosylglycinamide formyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide." [EC:2.1.2.2] +synonym: "10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity" EXACT [EC:2.1.2.2] +synonym: "2-amino-N-ribosylacetamide 5'-phosphate transformylase activity" EXACT [EC:2.1.2.2] +synonym: "5'-phosphoribosylglycinamide transformylase activity" EXACT [EC:2.1.2.2] +synonym: "5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.2] +synonym: "GAR formyltransferase activity" EXACT [EC:2.1.2.2] +synonym: "GAR TFase activity" EXACT [EC:2.1.2.2] +synonym: "GAR transformylase activity" EXACT [EC:2.1.2.2] +synonym: "GART activity" EXACT [EC:2.1.2.2] +synonym: "glycinamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.2] +xref: EC:2.1.2.2 +xref: MetaCyc:GART-RXN +xref: Reactome:R-HSA-73813 "GAR + 10-Formyl-THF => FGAR + THF" +xref: RHEA:15053 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0004645 +name: 1,4-alpha-oligoglucan phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase." [EC:2.4.1.1] +synonym: "1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.1] +synonym: "1,4-alpha-glucan phosphorylase activity" EXACT [EC:2.4.1.1] +synonym: "alpha-glucan phosphorylase" BROAD [EC:2.4.1.1] +synonym: "amylopectin phosphorylase" NARROW [EC:2.4.1.1] +synonym: "amylophosphorylase activity" NARROW [EC:2.4.1.1] +synonym: "glucan phosphorylase" NARROW [EC:2.4.1.1] +synonym: "glucosan phosphorylase" NARROW [EC:2.4.1.1] +synonym: "granulose phosphorylase" NARROW [EC:2.4.1.1] +synonym: "muscle phosphorylase" NARROW [EC:2.4.1.1] +synonym: "muscle phosphorylase a and b activity" NARROW [EC:2.4.1.1] +synonym: "myophosphorylase" NARROW [EC:2.4.1.1] +synonym: "polyphosphorylase activity" EXACT [EC:2.4.1.1] +synonym: "potato phosphorylase" NARROW [EC:2.4.1.1] +synonym: "starch phosphorylase" NARROW [EC:2.4.1.1] +xref: EC:2.4.1.1 +xref: MetaCyc:RXN-1826 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0004647 +name: phosphoserine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate." [EC:3.1.3.3] +synonym: "O-phosphoserine phosphohydrolase activity" EXACT [EC:3.1.3.3] +xref: EC:3.1.3.3 +xref: MetaCyc:PSERPHOSPHA-RXN +xref: Reactome:R-HSA-977324 "phosphoserine is dephosphorylated" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0004648 +name: O-phospho-L-serine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +alt_id: GO:0004646 +def: "Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate." [EC:2.6.1.52] +synonym: "3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.52] +synonym: "3-phosphoserine aminotransferase activity" EXACT [EC:2.6.1.52] +synonym: "3PHP transaminase activity" EXACT [EC:2.6.1.52] +synonym: "hydroxypyruvic phosphate--glutamic transaminase activity" EXACT [EC:2.6.1.52] +synonym: "L-phosphoserine aminotransferase activity" EXACT [EC:2.6.1.52] +synonym: "PdxC" RELATED [EC:2.6.1.52] +synonym: "phosphohydroxypyruvate transaminase activity" EXACT [EC:2.6.1.52] +synonym: "phosphohydroxypyruvic--glutamic transaminase activity" EXACT [EC:2.6.1.52] +synonym: "phosphoserine aminotransferase activity" BROAD [] +synonym: "phosphoserine transaminase activity" BROAD [EC:2.6.1.52] +synonym: "PSAT activity" EXACT [EC:2.6.1.52] +synonym: "SerC" RELATED [EC:2.6.1.52] +xref: EC:2.6.1.52 +xref: MetaCyc:PSERTRANSAM-RXN +xref: Reactome:R-HSA-977333 "3-phosphonooxypyruvic acid + L-glutamate = O-phospho-L-serine + 2-oxoglutarate" +xref: RHEA:14329 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004649 +name: poly(ADP-ribose) glycohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose." [EC:3.2.1.143] +xref: EC:3.2.1.143 +xref: MetaCyc:3.2.1.143-RXN +xref: Reactome:R-HSA-5651828 "PARG dePARylates PARP1,PARP2" +xref: Reactome:R-HSA-8952903 "ADPRHL2 hydrolyses poly(ADP-ribose)" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004650 +name: polygalacturonase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans." [EC:3.2.1.15] +synonym: "endo-D-galacturonase activity" EXACT [] +synonym: "endo-polygalacturonase activity" EXACT [] +synonym: "endogalacturonase activity" EXACT [] +synonym: "endopolygalacturonase activity" EXACT [] +synonym: "pectin depolymerase activity" NARROW [EC:3.2.1.15] +synonym: "pectin hydrolase activity" EXACT [EC:3.2.1.15] +synonym: "pectin polygalacturonase activity" EXACT [EC:3.2.1.15] +synonym: "pectinase activity" NARROW [EC:3.2.1.15] +synonym: "pectolase activity" EXACT [EC:3.2.1.15] +synonym: "poly(1,4-alpha-D-galacturonide) glycanohydrolase activity" EXACT [] +synonym: "poly-alpha-1,4-galacturonide glycanohydrolase activity" EXACT [] +xref: EC:3.2.1.15 +xref: MetaCyc:RXN-2103 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0004651 +name: polynucleotide 5'-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate." [EC:3.1.3.33] +synonym: "5'-polynucleotidase activity" EXACT [EC:3.1.3.33] +synonym: "polynucleotide 5'-phosphohydrolase activity" EXACT [EC:3.1.3.33] +synonym: "polynucleotide 5'-triphosphatase activity" EXACT [EC:3.1.3.33] +xref: EC:3.1.3.33 +xref: MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN +xref: Reactome:R-HSA-77078 "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme" +is_a: GO:0098518 ! polynucleotide phosphatase activity +relationship: part_of GO:0098507 ! polynucleotide 5' dephosphorylation + +[Term] +id: GO:0004652 +name: polynucleotide adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group." [EC:2.7.7.19] +synonym: "adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [EC:2.7.7.19] +synonym: "AMP polynucleotidylexotransferase activity" EXACT [EC:2.7.7.19] +synonym: "ATP-polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19] +synonym: "ATP:polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19] +synonym: "ATP:polynucleotidylexotransferase activity" EXACT [EC:2.7.7.19] +synonym: "NTP polymerase activity" EXACT [EC:2.7.7.19] +synonym: "poly(A) hydrolase activity" EXACT [EC:2.7.7.19] +synonym: "poly(A) polymerase activity" EXACT [EC:2.7.7.19] +synonym: "poly(A) synthetase activity" EXACT [EC:2.7.7.19] +synonym: "poly-A polymerase activity" EXACT [EC:2.7.7.19] +synonym: "polyadenylate nucleotidyltransferase activity" EXACT [EC:2.7.7.19] +synonym: "polyadenylate polymerase activity" EXACT [EC:2.7.7.19] +synonym: "polyadenylate synthetase activity" EXACT [EC:2.7.7.19] +synonym: "polyadenylic acid polymerase activity" EXACT [EC:2.7.7.19] +synonym: "polyadenylic polymerase activity" EXACT [EC:2.7.7.19] +synonym: "RNA adenylating enzyme activity" EXACT [EC:2.7.7.19] +synonym: "RNA formation factors, PF1" RELATED [EC:2.7.7.19] +synonym: "terminal riboadenylate transferase activity" EXACT [EC:2.7.7.19] +xref: EC:2.7.7.19 +xref: MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN +xref: Reactome:R-HSA-72185 "mRNA polyadenylation" +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0004653 +name: polypeptide N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis." [EC:2.4.1.41, ISBN:0879695595] +synonym: "glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "polypeptide-N-acetylgalactosamine transferase activity" EXACT [EC:2.4.1.41] +synonym: "protein-UDP acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +synonym: "UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity" EXACT [EC:2.4.1.41] +synonym: "uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] +xref: EC:2.4.1.41 +xref: MetaCyc:2.4.1.41-RXN +xref: Reactome:R-HSA-5096532 "Defective GALNT12 does not transfer GalNAc to mucins" +xref: Reactome:R-HSA-5096537 "Defective GALNT3 does not transfer GalNAc to mucins" +xref: Reactome:R-HSA-8851619 "GALNT3 transfers GalNAc to FGF23" +xref: Reactome:R-HSA-913675 "GALNTs transfer GalNAc from UDP-GalNAc to mucins to form Tn antigens" +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004654 +name: polyribonucleotide nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate." [EC:2.7.7.8] +synonym: "nucleoside diphosphate:polynucleotidyl transferase activity" EXACT [EC:2.7.7.8] +synonym: "polynucleotide phosphorylase activity" EXACT [EC:2.7.7.8] +synonym: "polyribonucleotide phosphorylase activity" EXACT [EC:2.7.7.8] +synonym: "polyribonucleotide:phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.8] +xref: EC:2.7.7.8 +xref: MetaCyc:2.7.7.8-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0004655 +name: porphobilinogen synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen." [EC:4.2.1.24, RHEA:24064] +synonym: "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)" EXACT [EC:4.2.1.24] +synonym: "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)" EXACT [EC:4.2.1.24] +synonym: "5-levulinic acid dehydratase activity" EXACT [EC:4.2.1.24] +synonym: "aminolevulinate dehydratase activity" EXACT [] +synonym: "aminolevulinic dehydratase activity" EXACT [EC:4.2.1.24] +synonym: "delta-aminolevulinate dehydratase activity" EXACT [EC:4.2.1.24] +synonym: "delta-aminolevulinic acid dehydrase activity" EXACT [EC:4.2.1.24] +synonym: "delta-aminolevulinic acid dehydratase activity" EXACT [] +synonym: "delta-aminolevulinic dehydratase activity" EXACT [EC:4.2.1.24] +xref: EC:4.2.1.24 +xref: KEGG_REACTION:R00036 +xref: MetaCyc:PORPHOBILSYNTH-RXN +xref: Reactome:R-HSA-189439 "ALAD condenses 2 dALAs to form PBG" +xref: RHEA:24064 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004656 +name: procollagen-proline 4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.2] +synonym: "collagen proline hydroxylase activity" EXACT [EC:1.14.11.2] +synonym: "hydroxylase, collagen proline activity" EXACT [EC:1.14.11.2] +synonym: "peptidyl proline hydroxylase activity" BROAD [EC:1.14.11.2] +synonym: "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity" EXACT [EC:1.14.11.2] +synonym: "procollagen-proline,2-oxoglutarate-4-dioxygenase activity" EXACT [] +synonym: "proline hydroxylase activity" BROAD [EC:1.14.11.2] +synonym: "proline protocollagen hydroxylase activity" EXACT [EC:1.14.11.2] +synonym: "proline, 2-oxoglutarate dioxygenase activity" BROAD [EC:1.14.11.2] +synonym: "proline,2-oxoglutarate 4-dioxygenase activity" BROAD [EC:1.14.11.2] +synonym: "prolyl 4-hydroxylase activity" BROAD [EC:1.14.11.2] +synonym: "prolyl hydroxylase activity" BROAD [EC:1.14.11.2] +synonym: "prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity" BROAD [EC:1.14.11.2] +synonym: "prolylprotocollagen dioxygenase activity" EXACT [EC:1.14.11.2] +synonym: "prolylprotocollagen hydroxylase activity" EXACT [EC:1.14.11.2] +synonym: "protocollagen hydroxylase activity" BROAD [EC:1.14.11.2] +synonym: "protocollagen proline 4-hydroxylase activity" EXACT [EC:1.14.11.2] +synonym: "protocollagen proline dioxygenase activity" EXACT [EC:1.14.11.2] +synonym: "protocollagen proline hydroxylase activity" EXACT [EC:1.14.11.2] +synonym: "protocollagen prolyl hydroxylase activity" EXACT [EC:1.14.11.2] +xref: EC:1.14.11.2 +xref: KEGG_REACTION:R03219 +xref: MetaCyc:1.14.11.2-RXN +xref: Reactome:R-HSA-1650808 "Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines" +is_a: GO:0019798 ! procollagen-proline dioxygenase activity +is_a: GO:0031545 ! peptidyl-proline 4-dioxygenase activity + +[Term] +id: GO:0004657 +name: proline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor." [EC:1.5.99.8] +synonym: "L-proline dehydrogenase activity" EXACT [EC:1.5.99.8] +synonym: "L-proline:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.8] +synonym: "L-proline:acceptor oxidoreductase activity" EXACT [EC:1.5.99.8] +xref: EC:1.5.99.8 +xref: MetaCyc:RXN-7181 +xref: Reactome:R-HSA-6784224 "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate" +xref: Reactome:R-HSA-70670 "PRODH oxidises L-Pro to 1PYR-5COOH" +xref: Reactome:R-HSA-8955817 "PRODH2 oxidises HPRO to 1PYR-5COOH" +xref: RHEA:23784 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0004658 +name: propionyl-CoA carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA." [EC:6.4.1.3] +synonym: "PCCase activity" EXACT [EC:6.4.1.3] +synonym: "propanoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.3] +synonym: "propionyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.3] +xref: EC:6.4.1.3 +xref: MetaCyc:PROPIONYL-COA-CARBOXY-RXN +xref: Reactome:R-HSA-71031 "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate" +xref: RHEA:23720 +is_a: GO:0016421 ! CoA carboxylase activity + +[Term] +id: GO:0004659 +name: prenyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor)." [GOC:mah] +xref: MetaCyc:GPPSYN-RXN +xref: Reactome:R-HSA-6806674 "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004660 +name: protein farnesyltransferase activity +namespace: molecular_function +alt_id: GO:0018223 +def: "Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate." [EC:2.5.1.58, PMID:8621375] +comment: The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate. +synonym: "CAAX farnesyltransferase activity" NARROW [EC:2.5.1.58] +synonym: "farnesyl-diphosphate:protein-cysteine farnesyltransferase activity" EXACT [EC:2.5.1.58] +synonym: "FTase activity" EXACT [EC:2.5.1.58] +synonym: "protein-cysteine farnesyltransferase activity" EXACT [] +xref: EC:2.5.1.58 +xref: MetaCyc:2.5.1.58-RXN +xref: Reactome:R-HSA-2530501 "FNTA:FNTB transfers FARN to GNGT1" +is_a: GO:0008318 ! protein prenyltransferase activity + +[Term] +id: GO:0004661 +name: protein geranylgeranyltransferase activity +namespace: molecular_function +alt_id: GO:0018224 +def: "Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein." [PMID:8621375] +synonym: "protein-cysteine geranylgeranyltransferase activity" EXACT [] +is_a: GO:0008318 ! protein prenyltransferase activity + +[Term] +id: GO:0004662 +name: CAAX-protein geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families." [EC:2.5.1.59, PMID:8621375] +synonym: "geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT [] +synonym: "geranylgeranyltransferase type I activity" EXACT [] +synonym: "GGTase-I activity" EXACT [] +synonym: "GGTaseI activity" EXACT [] +synonym: "protein geranylgeranyltransferase type I" RELATED [EC:2.5.1.59] +synonym: "type I protein geranyl-geranyltransferase activity" EXACT [EC:2.5.1.59] +xref: EC:2.5.1.59 +xref: MetaCyc:2.5.1.60-RXN +xref: MetaCyc:RXN-3701 +is_a: GO:0004661 ! protein geranylgeranyltransferase activity + +[Term] +id: GO:0004663 +name: Rab geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375] +synonym: "geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT [] +synonym: "GGTase-II activity" EXACT [] +synonym: "GGTaseII activity" EXACT [] +synonym: "protein geranylgeranyltransferase type II activity" EXACT [] +synonym: "Rab-protein geranylgeranyltransferase activity" EXACT [] +synonym: "RabGGTase activity" EXACT [] +synonym: "type II protein geranyl-geranyltransferase activity" EXACT [EC:2.5.1.60] +xref: EC:2.5.1.60 +xref: MetaCyc:2.5.1.60-RXN +xref: MetaCyc:RXN-3701 +is_a: GO:0004661 ! protein geranylgeranyltransferase activity + +[Term] +id: GO:0004664 +name: prephenate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2." [EC:4.2.1.51] +synonym: "prephenate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.51] +synonym: "prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)" EXACT [EC:4.2.1.51] +xref: EC:4.2.1.51 +xref: MetaCyc:PREPHENATEDEHYDRAT-RXN +xref: RHEA:21648 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004665 +name: prephenate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH." [EC:1.3.1.13, RHEA:21640] +synonym: "prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.3.1.13] +synonym: "prephenate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.13] +xref: EC:1.3.1.13 +xref: KEGG_REACTION:R01730 +xref: MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:21640 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004666 +name: prostaglandin-endoperoxide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [EC:1.14.99.1] +synonym: "(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.1] +synonym: "(PG)H synthase activity" EXACT [EC:1.14.99.1] +synonym: "fatty acid cyclooxygenase activity" EXACT [EC:1.14.99.1] +synonym: "PG synthetase activity" EXACT [EC:1.14.99.1] +synonym: "prostaglandin endoperoxide synthetase activity" EXACT [EC:1.14.99.1] +synonym: "prostaglandin G/H synthase activity" EXACT [EC:1.14.99.1] +synonym: "prostaglandin synthase activity" EXACT [EC:1.14.99.1] +synonym: "prostaglandin synthetase activity" EXACT [EC:1.14.99.1] +xref: EC:1.14.99.1 +xref: MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN +xref: Reactome:R-HSA-140355 "Arachidonic acid is oxidised to PGG2 by PTGS1" +xref: Reactome:R-HSA-2309787 "Arachidonic acid is oxidised to PGG2 by PTGS2" +xref: RHEA:23728 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0004667 +name: prostaglandin-D synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2)." [EC:5.3.99.2, RHEA:10600] +synonym: "(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity" EXACT [EC:5.3.99.2] +synonym: "PGD2 synthase activity" EXACT [EC:5.3.99.2] +synonym: "PGH-PGD isomerase activity" EXACT [EC:5.3.99.2] +synonym: "prostaglandin D2 synthase activity" EXACT [EC:5.3.99.2] +synonym: "prostaglandin-H2 D-isomerase activity" EXACT [EC:5.3.99.2] +synonym: "prostaglandin-R-prostaglandin D isomerase activity" EXACT [EC:5.3.99.2] +xref: EC:5.3.99.2 +xref: KEGG_REACTION:R02266 +xref: MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN +xref: Reactome:R-HSA-2161620 "PGH2 is isomerised to PGD2 by PTGDS" +xref: Reactome:R-HSA-2161701 "PGH2 is isomerised to PGD2 by HPGDS" +xref: RHEA:10600 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0004668 +name: protein-arginine deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3. This reaction is calcium-dependent." [PMID:27393304] +synonym: "peptidylarginine deiminase activity" EXACT [EC:3.5.3.15] +synonym: "protein-L-arginine iminohydrolase activity" EXACT [EC:3.5.3.15] +xref: EC:3.5.3.15 +xref: MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN +xref: Reactome:R-HSA-1183128 "PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins" +xref: Reactome:R-HSA-3247569 "PADI4 deiminates Histones" +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18666 xsd:anyURI + +[Term] +id: GO:0004671 +name: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0018225 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester." [EC:2.1.1.100] +synonym: "farnesyl cysteine C-terminal methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "farnesyl-protein carboxymethyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "farnesylated protein C-terminal O-methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "isoprenylated protein methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "isoprenylcysteine carboxylmethyltransferase activity" RELATED [EC:2.1.1.100] +synonym: "prenylated protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "prenylated protein methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "prenylcysteine carboxyl methyltransferase activity" RELATED [EC:2.1.1.100] +synonym: "prenylcysteine carboxylmethyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "prenylcysteine carboxymethyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "prenylcysteine methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "protein C-terminal farnesylcysteine O-methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "protein S-farnesylcysteine C-terminal methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "protein-S-isoprenylcysteine O-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity" EXACT [EC:2.1.1.100] +synonym: "S-farnesylcysteine methyltransferase activity" EXACT [EC:2.1.1.100] +xref: EC:2.1.1.100 +xref: KEGG_REACTION:R04496 +xref: MetaCyc:2.1.1.100-RXN +xref: Reactome:R-HSA-6788650 "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins" +is_a: GO:0003880 ! protein C-terminal carboxyl O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004672 +name: protein kinase activity +namespace: molecular_function +alt_id: GO:0050222 +def: "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN] +comment: Note that triphosphate is used as a phosphate donor by at least one kinase. +subset: goslim_aspergillus +subset: goslim_candida +synonym: "protamine kinase activity" NARROW [] +xref: MetaCyc:PROTEIN-KINASE-RXN +xref: Reactome:R-HSA-156832 "INF-gamma induced phosphorylation of L13a" +xref: Reactome:R-HSA-937034 "IRAK1 phosphorylates Pellino" +xref: Reactome:R-HSA-9604606 "Unknown kinase phosphorylates NICD4" +xref: Reactome:R-HSA-975139 "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006468 ! protein phosphorylation + +[Term] +id: GO:0004673 +name: protein histidine kinase activity +namespace: molecular_function +alt_id: GO:0008896 +def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine." [EC:2.7.13.3, GOC:mah] +synonym: "ATP:protein-L-histidine N-phosphotransferase activity" EXACT [EC:2.7.13.3] +synonym: "EnvZ" NARROW [EC:2.7.13.3] +synonym: "histidine kinase (ambiguous)" EXACT [EC:2.7.13.3] +synonym: "histidine kinase activity" EXACT [] +synonym: "histidine protein kinase (ambiguous)" EXACT [EC:2.7.13.3] +synonym: "histidine protein kinase activity" EXACT [EC:2.7.13.3] +synonym: "HK1" RELATED [EC:2.7.13.3] +synonym: "HP165" RELATED [EC:2.7.13.3] +synonym: "protein histidine kinase (ambiguous)" EXACT [EC:2.7.13.3] +synonym: "protein kinase (histidine)" EXACT [EC:2.7.13.3] +synonym: "protein kinase (histidine) (ambiguous)" EXACT [EC:2.7.13.3] +synonym: "protein-histidine kinase activity" EXACT [] +synonym: "Sln1p" NARROW [EC:2.7.13.3] +xref: EC:2.7.13.3 +xref: MetaCyc:2.7.13.3-RXN +is_a: GO:0004672 ! protein kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor +relationship: part_of GO:0018106 ! peptidyl-histidine phosphorylation + +[Term] +id: GO:0004674 +name: protein serine/threonine kinase activity +namespace: molecular_function +alt_id: GO:0004695 +alt_id: GO:0004696 +alt_id: GO:0004700 +def: "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:bf, RHEA:17989, RHEA:46608] +synonym: "protein kinase (phosphorylating) activity" NARROW [EC:2.7.11.1] +synonym: "protein phosphokinase activity" NARROW [EC:2.7.11.1] +synonym: "protein serine kinase activity" NARROW [EC:2.7.11.1] +synonym: "protein serine-threonine kinase activity" EXACT [EC:2.7.11.1] +synonym: "protein-serine kinase activity" NARROW [EC:2.7.11.1] +synonym: "serine kinase activity" NARROW [EC:2.7.11.1] +synonym: "serine protein kinase activity" NARROW [EC:2.7.11.1] +synonym: "serine(threonine) protein kinase activity" EXACT [EC:2.7.11.1] +synonym: "serine-specific protein kinase activity" NARROW [EC:2.7.11.1] +synonym: "serine/threonine protein kinase activity" EXACT [EC:2.7.11.1] +synonym: "threonine-specific protein kinase activity" NARROW [EC:2.7.11.1] +xref: Reactome:R-HSA-109702 "PDPK1 phosphorylates AKT2" +xref: Reactome:R-HSA-109822 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1" +xref: Reactome:R-HSA-109823 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2" +xref: Reactome:R-HSA-109860 "MAP2K1 phosphorylates MAPK3" +xref: Reactome:R-HSA-109862 "MAP2K2 phosphorylates MAPK1" +xref: Reactome:R-HSA-111919 "PKA phosphorylates CREB1" +xref: Reactome:R-HSA-111970 "PKC phosphorylates GRK2" +xref: Reactome:R-HSA-112342 "Inactivation of MAP2K1 by CDK1" +xref: Reactome:R-HSA-112381 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex" +xref: Reactome:R-HSA-1168635 "PRKCB (PKC-beta) phosphorylates CARMA1" +xref: Reactome:R-HSA-1168638 "Activated IKK phosphorylates I-kappaB" +xref: Reactome:R-HSA-1168641 "TAK1 associated with the CBM complex phosphorylates IKKbeta" +xref: Reactome:R-HSA-1181149 "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin" +xref: Reactome:R-HSA-1181156 "Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL" +xref: Reactome:R-HSA-1181355 "Phosphorylation of R-SMAD2/3 by NODAL receptor" +xref: Reactome:R-HSA-1225894 "Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL" +xref: Reactome:R-HSA-1358791 "Phosphorylation of USP8 by P-AKT" +xref: Reactome:R-HSA-1362270 "Phosphorylation of LIN52 component of MuvB by DYRK1A" +xref: Reactome:R-HSA-139908 "Phosphorylation of DLC2 by MAPK8" +xref: Reactome:R-HSA-139918 "Phosphorylation of BIM by JNK" +xref: Reactome:R-HSA-1445144 "p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4)" +xref: Reactome:R-HSA-1449597 "p-AKT2 phosphorylates Myosin 5A" +xref: Reactome:R-HSA-1454699 "AMPK-alpha2 phosphorylates TBC1D1" +xref: Reactome:R-HSA-1458463 "p-AKT2 phosphorylates RGC2" +xref: Reactome:R-HSA-1549526 "Phosphorylation of SMAD2/3 by Activin:Activin Receptor" +xref: Reactome:R-HSA-156673 "Regulation of KIF23 (MKLP1) by phosphorylation" +xref: Reactome:R-HSA-156678 "Activation of Cdc25C" +xref: Reactome:R-HSA-156682 "Regulation of NUDC by phosphorylation" +xref: Reactome:R-HSA-156699 "Inactivation of Wee1 kinase" +xref: Reactome:R-HSA-156723 "Regulation of KIF20A (MKL2) by phosphorylation" +xref: Reactome:R-HSA-1592233 "p38 MAPK phosphorylates PPARGC1A" +xref: Reactome:R-HSA-162363 "p-T309,S474-AKT2:PIP3 phosphorylates PDE3B" +xref: Reactome:R-HSA-162657 "Inactivation of Myt1 kinase" +xref: Reactome:R-HSA-163010 "Down Regulation of Emi1 through Phosphorylation of Emi1" +xref: Reactome:R-HSA-1632857 "ULK1 phosphorylates AMBRA1:Beclin-1 complex" +xref: Reactome:R-HSA-163416 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP" +xref: Reactome:R-HSA-163418 "perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP" +xref: Reactome:R-HSA-1638803 "Phosphorylation of cohesin by PLK1 at centromeres" +xref: Reactome:R-HSA-164151 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer" +xref: Reactome:R-HSA-165162 "Phosphorylation of TSC2 by PKB" +xref: Reactome:R-HSA-165182 "Phosphorylation of complexed TSC2 by PKB" +xref: Reactome:R-HSA-165692 "Phosphorylation of 4E-BP1 by activated mTORC1" +xref: Reactome:R-HSA-165718 "mTORC1 phosphorylation of RPS6KB1 (S6K)" +xref: Reactome:R-HSA-165726 "Phosphorylation of Ribosomal protein S6 by activated S6K1" +xref: Reactome:R-HSA-165758 "Phosphorylation and inactivation of eEF2K by activated S6K1" +xref: Reactome:R-HSA-165766 "Phosphorylation and activation of eIF4G by activated S6K1" +xref: Reactome:R-HSA-165777 "Phosphorylation and activation of eIF4B by activated S6K1" +xref: Reactome:R-HSA-166119 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal" +xref: Reactome:R-HSA-166245 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex" +xref: Reactome:R-HSA-166284 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP" +xref: Reactome:R-HSA-166286 "Multiple IRAK1 autophosphorylation steps" +xref: Reactome:R-HSA-167084 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex" +xref: Reactome:R-HSA-167098 "Phosphorylation (Ser5) of RNA pol II CTD" +xref: Reactome:R-HSA-168053 "Phosphorylated MAPKs phosphorylate ATF-2" +xref: Reactome:R-HSA-168140 "Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex" +xref: Reactome:R-HSA-170055 "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes" +xref: Reactome:R-HSA-170076 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes" +xref: Reactome:R-HSA-170087 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes" +xref: Reactome:R-HSA-170116 "Myt-1 mediated phosphorylation of Cyclin A:Cdc2" +xref: Reactome:R-HSA-170126 "Phosphorylation of Cyclin B1 in the CRS domain" +xref: Reactome:R-HSA-170977 "FRS2 is phosphorylated by active TrkA receptor" +xref: Reactome:R-HSA-174119 "Free APC/C phosphorylated by Plk1" +xref: Reactome:R-HSA-174174 "Phosphorylation of the Emi1 DSGxxS degron by Plk1" +xref: Reactome:R-HSA-176116 "Recruitment and activation of Chk1" +xref: Reactome:R-HSA-176298 "Activation of claspin" +xref: Reactome:R-HSA-187688 "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3" +xref: Reactome:R-HSA-187949 "CAK-mediated phosphorylation of Cyclin A:Cdk2" +xref: Reactome:R-HSA-188350 "CAK-mediated phosphorylation of Cyclin E:Cdk2" +xref: Reactome:R-HSA-193647 "IRAK is activated" +xref: Reactome:R-HSA-193705 "IKKbeta phosphorylates IkB causing NF-kB to dissociate" +xref: Reactome:R-HSA-195275 "Phosphorylation of APC component of the destruction complex" +xref: Reactome:R-HSA-195283 "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3" +xref: Reactome:R-HSA-195287 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3" +xref: Reactome:R-HSA-195300 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3" +xref: Reactome:R-HSA-195318 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha" +xref: Reactome:R-HSA-198270 "PDPK1 phosphorylates AKT at T308" +xref: Reactome:R-HSA-198347 "AKT phosphorylates BAD" +xref: Reactome:R-HSA-198371 "AKT phosphorylates GSK3" +xref: Reactome:R-HSA-198599 "AKT phosphorylates MDM2" +xref: Reactome:R-HSA-198609 "AKT phosphorylates TSC2, inhibiting it" +xref: Reactome:R-HSA-198611 "AKT phosphorylates IKKalpha" +xref: Reactome:R-HSA-198613 "AKT phosphorylates p21Cip1 and p27Kip1" +xref: Reactome:R-HSA-198621 "AKT phosphorylates caspase-9" +xref: Reactome:R-HSA-198640 "TORC2 (mTOR) phosphorylates AKT at S473" +xref: Reactome:R-HSA-198669 "p38MAPK phosphorylates MSK1" +xref: Reactome:R-HSA-198731 "ERK1/2 activates ELK1" +xref: Reactome:R-HSA-198746 "ERK1/2/5 activate RSK1/2/3" +xref: Reactome:R-HSA-198756 "ERK1/2 phosphorylates MSK1" +xref: Reactome:R-HSA-199298 "AKT phosphorylates CREB1" +xref: Reactome:R-HSA-199299 "AKT phosphorylates FOXO transcription factors" +xref: Reactome:R-HSA-199839 "AKT can phosphorylate RSK" +xref: Reactome:R-HSA-199863 "AKT can phosphorylate NR4A1 (NUR77)" +xref: Reactome:R-HSA-199895 "RSK1/2/3 phosphorylates CREB at Serine 133" +xref: Reactome:R-HSA-199910 "MSK1 activates ATF1" +xref: Reactome:R-HSA-199917 "MAPKAPK2 phosphorylates CREB at Serine 133" +xref: Reactome:R-HSA-199929 "ERK5 activates the transcription factor MEF2" +xref: Reactome:R-HSA-199935 "MSK1 activates CREB" +xref: Reactome:R-HSA-200143 "AKT phosphorylates AKT1S1 (PRAS40)" +xref: Reactome:R-HSA-200421 "Activation of cytosolic AMPK by phosphorylation" +xref: Reactome:R-HSA-201677 "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta" +xref: Reactome:R-HSA-201691 "Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI" +xref: Reactome:R-HSA-201717 "CSNK2-mediated phosphorylation of DVL" +xref: Reactome:R-HSA-202222 "Phosphorylation of PKC theta" +xref: Reactome:R-HSA-202437 "Phosphorylation of CARMA1" +xref: Reactome:R-HSA-202459 "Phosphorylation of Bcl10" +xref: Reactome:R-HSA-202500 "Activation of IKK complex" +xref: Reactome:R-HSA-202510 "Activation of TAK1-TAB2 complex" +xref: Reactome:R-HSA-202541 "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB" +xref: Reactome:R-HSA-2028284 "Phosphorylation of STK4 (MST1) and SAV1 by STK4" +xref: Reactome:R-HSA-2028555 "Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1)" +xref: Reactome:R-HSA-2028583 "Phosphorylation of YAP by LATS2" +xref: Reactome:R-HSA-2028589 "Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2)" +xref: Reactome:R-HSA-2028591 "Phosphorylation of STK3 (MST2) and SAV1 by STK3" +xref: Reactome:R-HSA-2028598 "Phosphorylation of YAP by LATS1" +xref: Reactome:R-HSA-2028629 "Phosphorylation of MOB1A and B by p-STK4 (p-MST1)" +xref: Reactome:R-HSA-2028635 "Phosphorylation of MOB1A and B by p-STK3 (p-MST2)" +xref: Reactome:R-HSA-2028661 "Phosphorylation of WWTR1 (TAZ) by LATS2" +xref: Reactome:R-HSA-2028670 "Phosphorylation of MOB1A and B by p-STK4(MST1)/N" +xref: Reactome:R-HSA-2028673 "Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N" +xref: Reactome:R-HSA-2028675 "Phosphorylation of MOB1A and B by p-STK3(MST2)/N" +xref: Reactome:R-HSA-2028679 "Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N" +xref: Reactome:R-HSA-2029454 "Autophosphorylation of PAK1" +xref: Reactome:R-HSA-2029460 "PAK1 phosphorylates LIMK1" +xref: Reactome:R-HSA-2029469 "p-ERK phosphorylates WAVEs and ABI" +xref: Reactome:R-HSA-2060328 "Phosphorylation of WWTR1 (TAZ) by LATS1" +xref: Reactome:R-HSA-209087 "IKBA is phosphorylated by Phospho IKKB kinase" +xref: Reactome:R-HSA-211164 "AKT phosphorylates FOXO1A" +xref: Reactome:R-HSA-211583 "Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197" +xref: Reactome:R-HSA-211650 "Autophosphorylation of PAK-2p34 in the activation loop" +xref: Reactome:R-HSA-2168079 "MASTL (GWL) phosphorylates ARPP19" +xref: Reactome:R-HSA-2176475 "Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9" +xref: Reactome:R-HSA-2214351 "PLK1 phosphorylates GORASP1" +xref: Reactome:R-HSA-2243938 "AKT1 E17K mutant is phosphorylated by TORC2 complex" +xref: Reactome:R-HSA-2243942 "PDPK1 phosphorylates AKT1 E17K mutant" +xref: Reactome:R-HSA-2294580 "PLK1 hyperphosphorylates Condensin II complex" +xref: Reactome:R-HSA-2396007 "IRF3 is phosphorylated by TBK1" +xref: Reactome:R-HSA-2399941 "AKT1 E17K mutant phosphorylates BAD" +xref: Reactome:R-HSA-2399966 "AKT1 E17K mutant phosphorylates GSK3" +xref: Reactome:R-HSA-2399969 "AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1" +xref: Reactome:R-HSA-2399977 "AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)" +xref: Reactome:R-HSA-2399981 "AKT1 E17K mutant phosphorylates MDM2" +xref: Reactome:R-HSA-2399982 "AKT1 E17K mutant phosphorylates TSC2, inhibiting it" +xref: Reactome:R-HSA-2399985 "AKT1 E17K mutant phosphorylates caspase-9" +xref: Reactome:R-HSA-2399988 "AKT1 E17K mutant phosphorylates NR4A1 (NUR77)" +xref: Reactome:R-HSA-2399992 "AKT1 E17K mutant phosphorylates forkhead box transcription factors" +xref: Reactome:R-HSA-2399996 "AKT1 E17K mutant phosphorylates CREB1" +xref: Reactome:R-HSA-2399999 "AKT1 E17K mutant phosphorylates RSK" +xref: Reactome:R-HSA-2400001 "AKT1 E17K mutant phosphorylates CHUK (IKKalpha)" +xref: Reactome:R-HSA-2422927 "MAPK3-3 or MAPK1 phosphorylate GORASP2" +xref: Reactome:R-HSA-2430535 "MASTL phosphorylates ENSA" +xref: Reactome:R-HSA-2466068 "Phosphorylation of cohesin by PLK1 at chromosomal arms" +xref: Reactome:R-HSA-2470508 "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin" +xref: Reactome:R-HSA-2529020 "CK2 phosphorylates condensin I subunits" +xref: Reactome:R-HSA-2562526 "PLK1 phosphorylates OPTN" +xref: Reactome:R-HSA-2574840 "AJUBA facilitates AURKA autophosphorylation" +xref: Reactome:R-HSA-2730856 "Autophosphorylation of PAK" +xref: Reactome:R-HSA-2730868 "Phosphorylation of MEK7 by MEKK1" +xref: Reactome:R-HSA-2730876 "Phosphorylation of IKK-beta by TAK1" +xref: Reactome:R-HSA-2730896 "Phosphorylation of MEK4 by MEKK1" +xref: Reactome:R-HSA-2730900 "Activation of TAK1 complex bound to pUb-TRAF6" +xref: Reactome:R-HSA-2984226 "PLK1 phosphorylates NEK9" +xref: Reactome:R-HSA-2984258 "NEK9 phosphorylates NEK6/NEK7" +xref: Reactome:R-HSA-2990880 "NEK6/NEK7 phosphorylates NUP98" +xref: Reactome:R-HSA-2993898 "VRK1/VRK2 phosphorylate BANF1" +xref: Reactome:R-HSA-3000310 "AURKA phosphorylates PLK1" +xref: Reactome:R-HSA-3000327 "PLK1 phosphorylates BORA" +xref: Reactome:R-HSA-3132737 "MAPKs phosphorylate ETS1 and ETS2" +xref: Reactome:R-HSA-3209160 "Activated ERKs phosphorylate ERF" +xref: Reactome:R-HSA-3222006 "STK11 (LKB1) phosphorylates NUAK1" +xref: Reactome:R-HSA-3222020 "NUAK1 phosphorylates TP53" +xref: Reactome:R-HSA-3228469 "MAP3K5 phosphorylates MKK3 and MKK6" +xref: Reactome:R-HSA-3229102 "p-MAPKAPK3 phosphorylates BMI1" +xref: Reactome:R-HSA-3229152 "MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1)" +xref: Reactome:R-HSA-3239014 "MAPKAPK5 phosphorylates TP53" +xref: Reactome:R-HSA-3239019 "Active p38 MAPK phosphorylates MAPKAPK5" +xref: Reactome:R-HSA-3249371 "TBK1 phosphorylates STAT6 at Ser407" +xref: Reactome:R-HSA-3371435 "Constitutive phosphorylation by GSK3" +xref: Reactome:R-HSA-3371531 "Constitutive phosphorylation by pERK1/2" +xref: Reactome:R-HSA-3371567 "DBC1 is phosphorylated by ATM/ART" +xref: Reactome:R-HSA-349426 "Phosphorylation of MDM4 by CHEK2" +xref: Reactome:R-HSA-349444 "Phosphorylation of COP1 at Ser-387 by ATM" +xref: Reactome:R-HSA-349455 "Phosphorylation of MDM4 by ATM" +xref: Reactome:R-HSA-374696 "Phosphorylation of L1 by p90rsk" +xref: Reactome:R-HSA-3769394 "AKT phosphorylates CBY1" +xref: Reactome:R-HSA-377186 "Activated Akt1 phosphorylates AKT1S1 (PRAS40)" +xref: Reactome:R-HSA-3772435 "WNT signaling stimulates CSNK1-dependent phosphorylation of DVL" +xref: Reactome:R-HSA-380272 "Plk1-mediated phosphorylation of Nlp" +xref: Reactome:R-HSA-381091 "IRE1 dimer autophosphorylates" +xref: Reactome:R-HSA-381111 "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK" +xref: Reactome:R-HSA-3857328 "RPS6KA1/2/3 phosphorylates CEBPB on S321" +xref: Reactome:R-HSA-3857329 "MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB" +xref: Reactome:R-HSA-3858480 "WNT-dependent phosphorylation of DVL" +xref: Reactome:R-HSA-389756 "AKT interacts and phosphorylates Cot" +xref: Reactome:R-HSA-392752 "Phosphorylation of L1 by CK-II" +xref: Reactome:R-HSA-3928577 "ROCK phosphorylates LIMK1,2" +xref: Reactome:R-HSA-3928608 "LIMK phosphorylates CFL1, inactivating it" +xref: Reactome:R-HSA-3928616 "Activated ROCK phosphorylates MRLCs" +xref: Reactome:R-HSA-3928620 "PAK1 autophosphorylates" +xref: Reactome:R-HSA-3928625 "PAKs autophosphorylate" +xref: Reactome:R-HSA-3928640 "PAKs phosphorylate MLC" +xref: Reactome:R-HSA-399939 "Autophosphorylation of PAK" +xref: Reactome:R-HSA-399944 "Phosphorylation of CRMPs by Cdk5" +xref: Reactome:R-HSA-399950 "Phosphorylation of cofilin by LIMK-1" +xref: Reactome:R-HSA-399951 "Phosphorylation of CRMPs by GSK3beta" +xref: Reactome:R-HSA-399952 "Phosphorylation of LIMK-1 by PAK" +xref: Reactome:R-HSA-399978 "Protein kinase C, alpha type phosphorylates MARCKS" +xref: Reactome:R-HSA-400382 "CSNK1E,CSNK1D phosphorylate CRY and PER proteins" +xref: Reactome:R-HSA-4088134 "PLK1 phosphorylates FOXM1" +xref: Reactome:R-HSA-419083 "Myosin phosphatase inactivation by ROCK" +xref: Reactome:R-HSA-419087 "LIM kinase phosphorylation by ROCK" +xref: Reactome:R-HSA-419197 "Myosin regulatory light chain phosphorylation by ROCK" +xref: Reactome:R-HSA-419644 "Transphosphorylation of pLIMK1" +xref: Reactome:R-HSA-428961 "Phosphorylation of cPLA2 by MAPK p38 alpha" +xref: Reactome:R-HSA-429016 "ALOX5 is phosphorylated by MAPKAP2" +xref: Reactome:R-HSA-429714 "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP" +xref: Reactome:R-HSA-432110 "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding" +xref: Reactome:R-HSA-4332358 "Dissociation of CaM and CAMK2 autophosphorylation" +xref: Reactome:R-HSA-4332363 "Autophosphorylation and activation of CAMK2" +xref: Reactome:R-HSA-4332388 "Activation of MAP3K7 in response to WNT" +xref: Reactome:R-HSA-4411383 "NLK phosphorylates TCF/LEF" +xref: Reactome:R-HSA-4411402 "Activation of NLK" +xref: Reactome:R-HSA-442724 "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)" +xref: Reactome:R-HSA-442739 "PDPK1 phosphorylates RSKs" +xref: Reactome:R-HSA-442832 "PAK phosphorylates cortactin" +xref: Reactome:R-HSA-445072 "Interaction of PAK1 with Rac1-GTP" +xref: Reactome:R-HSA-446694 "IRAK4 phosphorylates IRAK1" +xref: Reactome:R-HSA-446701 "IRAK4-activated IRAK1 autophosphorylates" +xref: Reactome:R-HSA-448948 "Phosphorylation of E proteins by p38 MAPK" +xref: Reactome:R-HSA-448955 "Phosphorylation of MEF2 proteins by p38" +xref: Reactome:R-HSA-450222 "Active p38 MAPK phosphorylates MAPKAPK2 or 3" +xref: Reactome:R-HSA-450325 "c-FOS activation by phospho ERK1/2" +xref: Reactome:R-HSA-450463 "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)" +xref: Reactome:R-HSA-450474 "MK2 phosphorylates BRF1" +xref: Reactome:R-HSA-450490 "Protein Kinase B/Akt phosphorylates BRF1" +xref: Reactome:R-HSA-450499 "Protein Kinase B (AKT) phosphorylates KSRP" +xref: Reactome:R-HSA-450827 "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2." +xref: Reactome:R-HSA-451152 "MAP kinase p38 phosphorylates KSRP" +xref: Reactome:R-HSA-451347 "Activation of JNK by DSCAM" +xref: Reactome:R-HSA-4551570 "VANGL2 is phosphorylated in response to WNT5A" +xref: Reactome:R-HSA-4608825 "DVL2 is phosphorylated after WNT5A binding to FZD" +xref: Reactome:R-HSA-4793911 "MAPKAPK2 phosphorylates HSF1" +xref: Reactome:R-HSA-5082387 "Phosphorylation of HSF1 at Ser230 induces transactivation" +xref: Reactome:R-HSA-5082405 "Phosphorylation of HSF1 at Ser326 induces transactivation" +xref: Reactome:R-HSA-5213464 "RIPK1 is phosphorylated" +xref: Reactome:R-HSA-5213466 "RIPK3 is phosphorylated" +xref: Reactome:R-HSA-5218814 "PAK2 autophorylates" +xref: Reactome:R-HSA-5218821 "PDK1 phosphorylates PKC" +xref: Reactome:R-HSA-5218826 "Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732" +xref: Reactome:R-HSA-5218854 "p-Y420-FYN is phosphorylated on S21" +xref: Reactome:R-HSA-5218906 "RIPK3 phosphorylates MLKL" +xref: Reactome:R-HSA-5218916 "p-MAPK2/3 phosphorylates HSP27" +xref: Reactome:R-HSA-5228811 "NFKBIA variant is not phosphorylated within IkBA:NF-kappaB" +xref: Reactome:R-HSA-5229343 "AXIN is phosphorylated in the destruction complex" +xref: Reactome:R-HSA-5260201 "p-AKT2 phosphorylates C2CD5" +xref: Reactome:R-HSA-5357472 "PAK1-3 autophosphorylates" +xref: Reactome:R-HSA-5357477 "PAK1-3 phosphorylates VE-cadherin" +xref: Reactome:R-HSA-5357831 "CYLD is phosphorylated by IKK" +xref: Reactome:R-HSA-5578777 "DMPK phosphorylates PLN" +xref: Reactome:R-HSA-5607722 "Active NIK phosphorylates IKKA dimer" +xref: Reactome:R-HSA-5607726 "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB" +xref: Reactome:R-HSA-5607732 "K63polyUb-TAK1 autophosphorylates" +xref: Reactome:R-HSA-5607742 "K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta" +xref: Reactome:R-HSA-5610718 "CK1 phosphorylates p-GLI2" +xref: Reactome:R-HSA-5610722 "CK1 phosphorylates p-GLI3" +xref: Reactome:R-HSA-5610730 "GSK3 phosphorylates p-GLI2" +xref: Reactome:R-HSA-5610732 "GSK3 phosphorylates p-GLI3" +xref: Reactome:R-HSA-5624473 "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit" +xref: Reactome:R-HSA-5624492 "PAK phosphorylates p21 RAF1 on S338" +xref: Reactome:R-HSA-5627775 "Autophosphorylation of PAK1,2,3" +xref: Reactome:R-HSA-5632670 "CSNK1A1 phosphorylates SMO dimer" +xref: Reactome:R-HSA-5632672 "ADRBK1 phosphorylates SMO dimer" +xref: Reactome:R-HSA-5635841 "GLI proteins are phosphorylated" +xref: Reactome:R-HSA-5635842 "ULK3 phosphorylates GLI" +xref: Reactome:R-HSA-5665868 "AMPK (complex) phosphorylates ULK1 (complex)" +xref: Reactome:R-HSA-5666160 "AURKB phosphorylates DIAPH2-2 at kinetochores" +xref: Reactome:R-HSA-5668545 "NIK autophosphorylates on T559" +xref: Reactome:R-HSA-5668932 "PAK2 phosphorylates myosin regulatory light chain (MRLC)" +xref: Reactome:R-HSA-5668947 "PAK1 phosphorylates myosin phosphatase" +xref: Reactome:R-HSA-5668984 "PAK1 or PAK2 phosphorylates MYLK" +xref: Reactome:R-HSA-5669250 "PAK1 phosphorylates FLNA" +xref: Reactome:R-HSA-5671763 "p-T774-PKN1 phosphorylates PPP1R14A" +xref: Reactome:R-HSA-5671919 "Activated CIT phosphorylates MRLCs" +xref: Reactome:R-HSA-5672008 "Thr-180 of ULK1 is phosphorylated" +xref: Reactome:R-HSA-5672010 "Active mTORC1 phosphorylates ULK1" +xref: Reactome:R-HSA-5672828 "mTORC1 phosphorylates AKT1S1" +xref: Reactome:R-HSA-5672948 "MARK3 phosphorylates KSR1" +xref: Reactome:R-HSA-5672973 "MAP2Ks phosphorylate MAPKs" +xref: Reactome:R-HSA-5672978 "RAF phosphorylates MAP2K dimer" +xref: Reactome:R-HSA-5674496 "Activated MAPKs phosphorylate MAP2K1" +xref: Reactome:R-HSA-5675194 "Activated MAPK phosphorylates RAF1" +xref: Reactome:R-HSA-5675198 "Activated MAPKs phosphorylate BRAF" +xref: Reactome:R-HSA-5675868 "ULK1 phosphorylates ATG13 and RB1CC1" +xref: Reactome:R-HSA-5679205 "ULK1 phosphorylates Beclin-1" +xref: Reactome:R-HSA-5682026 "MRN bound to shortened telomeres activates ATM" +xref: Reactome:R-HSA-5682101 "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer" +xref: Reactome:R-HSA-5682598 "ATM phosphorylates HERC2" +xref: Reactome:R-HSA-5682983 "ATM phosphorylates WHSC1" +xref: Reactome:R-HSA-5683425 "ATM phosphorylates TP53BP1 at DNA DSBs" +xref: Reactome:R-HSA-5683792 "p-T68-CHEK2 autophosphorylates" +xref: Reactome:R-HSA-5683801 "CHEK2 phosphorylates BRCA1" +xref: Reactome:R-HSA-5683964 "ATM phosphorylates EYA1-4" +xref: Reactome:R-HSA-5684096 "CDK2 phosphorylates RBBP8" +xref: Reactome:R-HSA-5684140 "ATM phosphorylates RBBP8" +xref: Reactome:R-HSA-5684887 "Activation of CHEK1 at resected DNA DSBs" +xref: Reactome:R-HSA-5685156 "ATR phosphorylates RPA2" +xref: Reactome:R-HSA-5685230 "CHEK1 phosphorylates RAD51" +xref: Reactome:R-HSA-5685242 "CHEK1 phosphorylates BRCA2" +xref: Reactome:R-HSA-5686578 "Activated ATM phosphorylates ABL1" +xref: Reactome:R-HSA-5686704 "Activated ATM phosphorylates DCLRE1C" +xref: Reactome:R-HSA-5687086 "PAK1,2,3 phosphorylates MAPK6,4" +xref: Reactome:R-HSA-5687090 "p-S MAPK6 phosphorylates NCOA3" +xref: Reactome:R-HSA-5687094 "p-S MAPK6,4 phosphorylate MAPKAPK5" +xref: Reactome:R-HSA-5687101 "p-T182 MAPKAPK5 phosphorylates FOXO3" +xref: Reactome:R-HSA-5687121 "p-S MAPKAPK5 phosphorylates HSPB1" +xref: Reactome:R-HSA-5687183 "PRKDC phosphorylates DCLRE1C at DNA DSBs" +xref: Reactome:R-HSA-5690250 "p-T182-MAPKAPK5 phoshphorylates DNAJB1" +xref: Reactome:R-HSA-5692768 "MAPKAPK5 phosphorylates KALRN" +xref: Reactome:R-HSA-5692775 "SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs" +xref: Reactome:R-HSA-5692779 "p-S182 MAPKAPK5 phosphorylates FOXO1" +xref: Reactome:R-HSA-5693536 "ATM phosphorylates MDC1" +xref: Reactome:R-HSA-5693540 "MRN activates ATM" +xref: Reactome:R-HSA-5693549 "ATM phosphorylates histone H2AFX on S139 at DNA DSBs" +xref: Reactome:R-HSA-5693551 "Phosphorylation of BRCA1-A complex at multiple sites by ATM" +xref: Reactome:R-HSA-5693575 "DNA-PKcs autophosphorylates" +xref: Reactome:R-HSA-5693598 "ATM phosphorylates NBN" +xref: Reactome:R-HSA-5693609 "ATM phosphorylates TP53 at S15" +xref: Reactome:R-HSA-5694441 "CSNK1D phosphorylates SEC23" +xref: Reactome:R-HSA-6788392 "ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA" +xref: Reactome:R-HSA-6795290 "TORC2 complex phosphorylates SGK1" +xref: Reactome:R-HSA-6795460 "SGK1 phosphorylates MDM2" +xref: Reactome:R-HSA-6795473 "PDPK1 phosphorylates SGK1" +xref: Reactome:R-HSA-6798372 "ATM phosphorylates DYRK2" +xref: Reactome:R-HSA-6798374 "DYRK2 phosphorylates TP53" +xref: Reactome:R-HSA-6799097 "ATM phosphorylates ZNF420" +xref: Reactome:R-HSA-6799246 "CHEK1 phosphorylates TP53" +xref: Reactome:R-HSA-6799332 "ATR phosphorylates TP53" +xref: Reactome:R-HSA-6799409 "HIPK2 phosphorylates TP53" +xref: Reactome:R-HSA-6800490 "ATM phosphorylates PIDD1" +xref: Reactome:R-HSA-6801666 "PLK2 phosphorylates CENPJ" +xref: Reactome:R-HSA-6801675 "PLK2 phosphorylates NPM1" +xref: Reactome:R-HSA-6802911 "High kinase activity BRAF complexes phosphorylate MAP2Ks" +xref: Reactome:R-HSA-6802919 "RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks" +xref: Reactome:R-HSA-6802926 "Mutant RAS:p-RAF complexes phosphorylate MAP2Ks" +xref: Reactome:R-HSA-6802933 "p-BRAF and RAF fusion dimers phosphorylate MAP2Ks" +xref: Reactome:R-HSA-6802935 "MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers" +xref: Reactome:R-HSA-6802943 "RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks" +xref: Reactome:R-HSA-6802973 "PLK3 phosphorylates CDC25C" +xref: Reactome:R-HSA-6804266 "CHEK2 phosphorylates TTC5" +xref: Reactome:R-HSA-6804276 "ATM phosphorylates TTC5" +xref: Reactome:R-HSA-6804955 "ATM phosphorylates MDM2" +xref: Reactome:R-HSA-6805059 "CK2:FACT phosphorylates TP53" +xref: Reactome:R-HSA-6805103 "AURKA phosphorylates TP53" +xref: Reactome:R-HSA-6805126 "AURKB phosphorylates TP53" +xref: Reactome:R-HSA-6805276 "CDK5 phosphorylates TP53" +xref: Reactome:R-HSA-6805285 "PLK3 phosphorylates TP53" +xref: Reactome:R-HSA-6805399 "TAF1 phosphorylates TP53" +xref: Reactome:R-HSA-6805479 "TP53RK phosphorylates TP53" +xref: Reactome:R-HSA-6805640 "AKT phosphorylates KAT6A" +xref: Reactome:R-HSA-6805785 "AKT phosphorylates PHF20" +xref: Reactome:R-HSA-6810233 "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter" +xref: Reactome:R-HSA-6811454 "MAPKs phosphorylate PP2A" +xref: Reactome:R-HSA-6814409 "CK2 phosphorylates PDCL" +xref: Reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine" +xref: Reactome:R-HSA-69604 "Phosphorylation of Cdc25A at Ser-123 by Chk1" +xref: Reactome:R-HSA-69608 "Phosphorylation of Cdc25A at Ser-123 by Chk2" +xref: Reactome:R-HSA-69685 "CHEK2 phosphorylates TP53" +xref: Reactome:R-HSA-69891 "Phosphorylation and activation of CHEK2 by ATM" +xref: Reactome:R-HSA-75010 "Phosphorylation of Cdc25C at Ser 216 by Chk1" +xref: Reactome:R-HSA-75028 "Phosphorylation of Wee1 kinase by Chk1" +xref: Reactome:R-HSA-75809 "Phosphorylation of Cdc25C at Ser216 by CHEK2" +xref: Reactome:R-HSA-75820 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta" +xref: Reactome:R-HSA-77071 "Phosphorylation (Ser5) of RNA pol II CTD" +xref: Reactome:R-HSA-8850945 "Casein kinase II phosphorylates PTEN" +xref: Reactome:R-HSA-8852306 "Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends" +xref: Reactome:R-HSA-8852317 "PLK1 phosphorylates GTSE1" +xref: Reactome:R-HSA-8853419 "TPX2 promotes AURKA autophosphorylation" +xref: Reactome:R-HSA-8853444 "AURKA phosphorylates PHLDA1" +xref: Reactome:R-HSA-8854908 "PKA phosphorylates RET:GDNF:GFRA dimer" +xref: Reactome:R-HSA-8856813 "AAK1 phosphorylates AP-2 mu subunit at T156" +xref: Reactome:R-HSA-8863007 "p25-bound CDK5 phosphorylates CDC25B" +xref: Reactome:R-HSA-8863011 "p25-bound CDK5 phosphorylates CDC25C" +xref: Reactome:R-HSA-8863014 "p25-bound CDK5 phosphorylates CDC25A" +xref: Reactome:R-HSA-8863895 "IKKB phosphorylates SNAP23" +xref: Reactome:R-HSA-8868260 "CDK5:p25 phosphorylates GOLGA2" +xref: Reactome:R-HSA-8868340 "CDK5:p25 phosphorylates lamin B1" +xref: Reactome:R-HSA-8868344 "CDK5:p25 phosphorylates lamin A" +xref: Reactome:R-HSA-8868567 "CDK5:p25 phosphorylates PRDX1" +xref: Reactome:R-HSA-8868573 "CDK5:p25 phosphorylates PRDX2" +xref: Reactome:R-HSA-8868666 "CDK5:p25 phosphorylates JUN" +xref: Reactome:R-HSA-8870558 "CDK5:p25 phosphorylates FOXO3" +xref: Reactome:R-HSA-8873929 "Casein kinase II phosphorylates STARD10" +xref: Reactome:R-HSA-8876446 "p-ULK1 phosphorylates DENND3" +xref: Reactome:R-HSA-8877691 "MAP2K6 phosphorylates PIP4K2B" +xref: Reactome:R-HSA-8878050 "HIPK2 phosphorylates RUNX1 and EP300" +xref: Reactome:R-HSA-8878054 "HIPK2 phosphorylates RUNX1" +xref: Reactome:R-HSA-8933446 "Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling" +xref: Reactome:R-HSA-8939963 "Activated AKT phosphorylates RUNX2" +xref: Reactome:R-HSA-8940100 "CDK1 phosphorylates VCPIP1" +xref: Reactome:R-HSA-8942836 "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6" +xref: Reactome:R-HSA-8944454 "mTORC1 phosphorylates MAF1" +xref: Reactome:R-HSA-8948039 "FUNDC1 is phosphorylated by CK2" +xref: Reactome:R-HSA-8948146 "FUNDC1 is phosphorylated by ULK1 at Ser17" +xref: Reactome:R-HSA-8948757 "AKT phosphorylates MKRN1" +xref: Reactome:R-HSA-8952289 "FAM20C phosphorylates FAM20C substrates" +xref: Reactome:R-HSA-9007539 "CHEK1 phosphorylates E2F6" +xref: Reactome:R-HSA-9008480 "GSK3B phosphorylates RUNX2" +xref: Reactome:R-HSA-9008822 "PPM1D dephosphorylates RUNX2" +xref: Reactome:R-HSA-9009208 "Activated ERKs phosphorylate RUNX2" +xref: Reactome:R-HSA-9012319 "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD" +xref: Reactome:R-HSA-9013978 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex" +xref: Reactome:R-HSA-9022314 "HIPK2 phosphorylates MECP2" +xref: Reactome:R-HSA-9023132 "AURKB phosphorylates MECP2 at S423" +xref: Reactome:R-HSA-9032751 "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3" +xref: Reactome:R-HSA-9032863 "CDK5 phosphorylates NTRK2" +xref: Reactome:R-HSA-912470 "ATR phosphorylates Histone H2A.X at unsynapsed regions" +xref: Reactome:R-HSA-913996 "PKA/PKG phosphorylate Rap1GAP2" +xref: Reactome:R-HSA-918229 "Phosphorylation and release of IRF3/IRF7" +xref: Reactome:R-HSA-933525 "Phosphorylation and release of IRF7" +xref: Reactome:R-HSA-934559 "SPRY2 is phosphorylated by phosphorylated MNK1" +xref: Reactome:R-HSA-936951 "Activation of TAK1 complex bound to activated TLR4 complex" +xref: Reactome:R-HSA-937022 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP" +xref: Reactome:R-HSA-937059 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex" +xref: Reactome:R-HSA-9604328 "AKT1 phosphorylates NOTCH4" +xref: Reactome:R-HSA-9612980 "BRAF in Rap1-GTP complex:BRAF complex autophosphorylates" +xref: Reactome:R-HSA-9619515 "AMPK phosphorylates MAPT" +xref: Reactome:R-HSA-9619843 "ERKs phosphorylate RSKs" +xref: Reactome:R-HSA-9620004 "RSKs autophosphorylate" +xref: Reactome:R-HSA-9624526 "AKT phosphorylates FOXO3 downstream of ESR1 and EGFR" +xref: Reactome:R-HSA-9626880 "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345" +xref: Reactome:R-HSA-9627089 "CASP9 is phosphorylated at T125" +xref: Reactome:R-HSA-9632868 "CDKN1B is phosphorylated in response to estrogen" +xref: Reactome:R-HSA-9634702 "LINC01139 promotes phosphorylation of HIF1A by LRRK2" +xref: Reactome:R-HSA-975125 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9" +xref: Reactome:R-HSA-975134 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9" +xref: Reactome:R-HSA-975160 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9" +xref: Reactome:R-HSA-975170 "IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9" +xref: Reactome:R-HSA-975180 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9" +xref: Reactome:R-HSA-975853 "Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR" +xref: Reactome:R-HSA-975861 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex" +xref: Reactome:R-HSA-975865 "IRAK4 autophosphorylation within the complex activated TLR:MyD88" +xref: Reactome:R-HSA-975874 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex" +xref: Reactome:R-HSA-975878 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR" +xref: RHEA:17989 +xref: RHEA:46608 +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0004675 +name: transmembrane receptor protein serine/threonine kinase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [EC:2.7.11.30] +synonym: "activin receptor kinase activity" NARROW [EC:2.7.11.30] +synonym: "ATP:receptor-protein phosphotransferase activity" EXACT [EC:2.7.11.30] +synonym: "receptor protein serine/threonine kinase activity" EXACT [EC:2.7.11.30] +synonym: "receptor serine/threonine protein kinase activity" EXACT [EC:2.7.11.30] +synonym: "receptor type I serine/threonine protein kinase activity" NARROW [EC:2.7.11.30] +synonym: "receptor type II serine/threonine protein kinase activity" NARROW [EC:2.7.11.30] +synonym: "STK13" RELATED [EC:2.7.11.30] +synonym: "TGF-beta kinase activity" NARROW [EC:2.7.11.30] +xref: EC:2.7.11.30 +xref: MetaCyc:2.7.11.30-RXN +xref: Reactome:R-HSA-170868 "Activated type I receptor phosphorylates SMAD2/3 directly" +xref: Reactome:R-HSA-198732 "STAT3 activation" +xref: Reactome:R-HSA-201476 "Activated type I receptor phosphorylates R-Smad1/5/8 directly" +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0019199 ! transmembrane receptor protein kinase activity +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway + +[Term] +id: GO:0004676 +name: 3-phosphoinositide-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a phosphatidylinositol-3-phosphate." [GOC:mah] +synonym: "PDK activity" RELATED [PMID:10075713] +synonym: "phosphatidylinositol-3-phosphate protein kinase activity" EXACT [] +xref: Reactome:R-HSA-437195 "PDPK1 activates PRKCZ" +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004677 +name: DNA-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA." [GOC:mah] +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004679 +name: AMP-activated protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP." [GOC:mah] +synonym: "5'-AMP-activated protein kinase activity" EXACT [] +synonym: "AMPK activity" RELATED [GOC:mah] +synonym: "SNF1A/AMP-activated protein kinase activity" NARROW [] +xref: EC:2.7.11.11 +xref: Reactome:R-HSA-1592244 "AMPK phosphorylates PPARGC1A" +xref: Reactome:R-HSA-163691 "Phosphorylation of ChREBP at Serine 568 by AMPK" +xref: Reactome:R-HSA-200423 "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis" +xref: Reactome:R-HSA-380927 "p-AMPK phosphorylates TSC1:TSC2" +xref: Reactome:R-HSA-447074 "AMPK phosphorylates Raptor in the mTORC1 complex" +xref: Reactome:R-HSA-5673768 "p-AMPK:AMP phosphorylates Raptor in the mTORC1 complex" +xref: Reactome:R-HSA-6805470 "AMPK phosphorylates TP53" +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: has_part GO:0016208 ! AMP binding + +[Term] +id: GO:0004680 +name: obsolete casein kinase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "casein kinase activity" EXACT [] +xref: EC:2.7.11 +is_obsolete: true +replaced_by: GO:0004674 + +[Term] +id: GO:0004681 +name: obsolete casein kinase I activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "casein kinase I activity" EXACT [] +xref: EC:2.7.11 +is_obsolete: true +replaced_by: GO:0004674 + +[Term] +id: GO:0004682 +name: obsolete protein kinase CK2 activity +namespace: molecular_function +alt_id: GO:0008604 +def: "OBSOLETE. Catalysis of the reaction: casein + ATP = phosphocasein + ADP." [EC:2.7.11.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "casein kinase II activity" RELATED [] +synonym: "casein kinase II, catalytic activity" EXACT [] +synonym: "protein kinase CK2 activity" EXACT [] +synonym: "protein kinase CK2, intrinsic catalyst activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004674 + +[Term] +id: GO:0004683 +name: calmodulin-dependent protein kinase activity +namespace: molecular_function +alt_id: GO:0004684 +alt_id: GO:0004685 +alt_id: GO:0004688 +def: "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin." [GOC:mah, PMID:11264466] +synonym: "ATP:caldesmon O-phosphotransferase activity" NARROW [EC:2.7.11.17] +synonym: "ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity" EXACT [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase 1 activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase activity" EXACT [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase II activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase IV activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase kinase activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/calmodulin-dependent protein kinase kinase beta activity" NARROW [EC:2.7.11.17] +synonym: "Ca2+/CaM-dependent kinase activity" EXACT [] +synonym: "calcium- and calmodulin-dependent protein kinase activity" EXACT [] +synonym: "calcium/calmodulin-dependent protein kinase activity" EXACT [EC:2.7.11.17] +synonym: "calcium/calmodulin-dependent protein kinase type II activity" NARROW [EC:2.7.11.17] +synonym: "caldesmon kinase (phosphorylating) activity" NARROW [EC:2.7.11.17] +synonym: "calmodulin regulated protein kinase activity" EXACT [] +synonym: "calmodulin-dependent kinase II activity" NARROW [EC:2.7.11.17] +synonym: "calmodulin-dependent protein kinase I activity" NARROW [] +synonym: "CaM kinase activity" EXACT [EC:2.7.11.17] +synonym: "CaM kinase II activity" NARROW [EC:2.7.11.17] +synonym: "CAM PKII" RELATED [EC:2.7.11.17] +synonym: "CaM-regulated serine/threonine kinase activity" EXACT [EC:2.7.11.17] +synonym: "CaMKI" RELATED [EC:2.7.11.17] +synonym: "CaMKII" RELATED [EC:2.7.11.17] +synonym: "CaMKIV" RELATED [EC:2.7.11.17] +synonym: "CaMKKalpha" RELATED [EC:2.7.11.17] +synonym: "CaMKKbeta" RELATED [EC:2.7.11.17] +synonym: "microtubule-associated protein 2 kinase activity" RELATED [EC:2.7.11.17] +synonym: "multifunctional calcium- and calmodulin-regulated protein kinase activity" RELATED [] +synonym: "multifunctional calcium/calmodulin regulated protein kinase activity" RELATED [] +synonym: "STK20" RELATED [EC:2.7.11.17] +xref: EC:2.7.11.17 +xref: MetaCyc:2.7.11.17-RXN +xref: Reactome:R-HSA-111912 "CaMK4 phosphorylates CREB1" +xref: Reactome:R-HSA-111915 "CAMK4 autophosphorylates" +xref: Reactome:R-HSA-416320 "Trafficking of GluR1-containing AMPA receptors" +xref: Reactome:R-HSA-442749 "CaMKK autophosphorylates in the nucleus" +xref: Reactome:R-HSA-9006992 "MECP2 is phosphorylated at S423" +xref: Reactome:R-HSA-9617583 "CaMKII autophosphorylates" +xref: Reactome:R-HSA-9618750 "CaMKII phosphorylates AMPA receptor" +xref: Reactome:R-HSA-9619125 "CaMKK phosphorylates CAMK4" +xref: Reactome:R-HSA-9619355 "CaMKK autophosphorylates in the cytosol" +xref: Reactome:R-HSA-9619367 "CaMKKs phosphorylate CAMK1" +xref: Reactome:R-HSA-9619478 "CAMKK2 phosphorylates AMPK" +xref: Reactome:R-HSA-9619783 "CAMK1 phosphorylates ARHGEF7-1" +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004686 +name: elongation factor-2 kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate." [EC:2.7.11.20, MetaCyc:2.7.11.20-RXN] +synonym: "ATP:elongation factor 2 phosphotransferase activity" EXACT [EC:2.7.11.20] +synonym: "Ca/CaM-kinase III activity" EXACT [EC:2.7.11.20] +synonym: "calmodulin-dependent protein kinase III activity" EXACT [EC:2.7.11.20] +synonym: "CaM kinase III activity" EXACT [EC:2.7.11.20] +synonym: "eEF-2 kinase activity" EXACT [] +synonym: "eEF2 kinase activity" EXACT [EC:2.7.11.20] +synonym: "eEF2K" RELATED [EC:2.7.11.20] +synonym: "EF2K" RELATED [EC:2.7.11.20] +synonym: "elongation factor 2 kinase activity" EXACT [EC:2.7.11.20] +synonym: "eukaryotic elongation factor 2 kinase activity" EXACT [EC:2.7.11.20] +synonym: "STK19" RELATED [EC:2.7.11.20] +xref: EC:2.7.11.20 +xref: MetaCyc:2.7.11.20-RXN +is_a: GO:0004683 ! calmodulin-dependent protein kinase activity + +[Term] +id: GO:0004687 +name: myosin light chain kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate." [EC:2.7.11.18] +synonym: "ATP:myosin-light-chain O-phosphotransferase" BROAD [EC:2.7.11.18] +synonym: "ATP:myosin-light-chain O-phosphotransferase activity" EXACT [EC:2.7.11.18] +synonym: "calcium/calmodulin-dependent myosin light chain kinase activity" EXACT [EC:2.7.11.18] +synonym: "MLCK" RELATED [EC:2.7.11.18] +synonym: "MLCkase activity" EXACT [EC:2.7.11.18] +synonym: "myosin kinase activity" EXACT [EC:2.7.11.18] +synonym: "myosin light chain protein kinase activity" EXACT [EC:2.7.11.18] +synonym: "myosin light-chain kinase" BROAD [EC:2.7.11.18] +synonym: "myosin light-chain kinase (phosphorylating)" EXACT [EC:2.7.11.18] +synonym: "myosin light-chain kinase (phosphorylating) activity" EXACT [EC:2.7.11.18] +synonym: "myosin light-chain kinase activity" EXACT [EC:2.7.11.18] +synonym: "myosin-light-chain kinase activity" EXACT [] +synonym: "smooth-muscle-myosin-light-chain kinase activity" NARROW [EC:2.7.11.18] +synonym: "STK18" RELATED [EC:2.7.11.18] +xref: EC:2.7.11.18 +xref: MetaCyc:2.7.11.18-RXN +xref: Reactome:R-HSA-445813 "Phosphorylation of Smooth Muscle Myosin Light Chains" +xref: Reactome:R-HSA-5668978 "MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex" +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004689 +name: phosphorylase kinase activity +namespace: molecular_function +alt_id: GO:0008606 +def: "Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a." [EC:2.7.11.19] +synonym: "ATP:phosphorylase-b phosphotransferase activity" EXACT [EC:2.7.11.19] +synonym: "dephosphophosphorylase kinase activity" EXACT [EC:2.7.11.19] +synonym: "glycogen phosphorylase kinase activity" EXACT [EC:2.7.11.19] +synonym: "PHK" RELATED [EC:2.7.11.19] +synonym: "phosphorylase B kinase activity" EXACT [EC:2.7.11.19] +synonym: "phosphorylase kinase (phosphorylating) activity" EXACT [EC:2.7.11.19] +synonym: "phosphorylase kinase, intrinsic catalyst activity" EXACT [] +synonym: "STK17" RELATED [EC:2.7.11.19] +xref: EC:2.7.11.19 +xref: MetaCyc:2.7.11.19-RXN +xref: Reactome:R-HSA-453337 "glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP" +xref: Reactome:R-HSA-71541 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP" +xref: Reactome:R-HSA-71588 "glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP" +is_a: GO:0004683 ! calmodulin-dependent protein kinase activity + +[Term] +id: GO:0004690 +name: cyclic nucleotide-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide." [GOC:mah] +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: has_part GO:0030551 ! cyclic nucleotide binding + +[Term] +id: GO:0004691 +name: cAMP-dependent protein kinase activity +namespace: molecular_function +alt_id: GO:0008602 +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP." [EC:2.7.11.11] +synonym: "3',5' cAMP-dependent protein kinase activity" EXACT [] +synonym: "3',5'-cAMP-dependent protein kinase activity" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [] +synonym: "AMPK" RELATED [EC:2.7.11.11] +synonym: "ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [EC:2.7.11.11] +synonym: "cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [] +synonym: "cyclic AMP-dependent protein kinase activity" EXACT [] +synonym: "PKA" RELATED [EC:2.7.11.11] +synonym: "PKA C" RELATED [EC:2.7.11.11] +synonym: "protein kinase A activity" BROAD [EC:2.7.11.11] +synonym: "STK22" RELATED [EC:2.7.11.11] +xref: EC:2.7.11.11 +xref: MetaCyc:2.7.11.11-RXN +xref: Reactome:R-HSA-163672 "Phosphorylation of ChREBP at Thr(666) by PKA" +xref: Reactome:R-HSA-163676 "Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA" +xref: Reactome:R-HSA-163773 "Phosphorylation of PF2K-Pase by PKA catalytic subunit" +xref: Reactome:R-HSA-177275 "PKA phosphorylates DARPP-32 on Thr34" +xref: Reactome:R-HSA-177284 "PKA phosphorylates PDE4B" +xref: Reactome:R-HSA-432232 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)" +xref: Reactome:R-HSA-5610717 "PKA phosphorylates GLI2" +xref: Reactome:R-HSA-5610720 "PKA phosphorylates GLI3" +xref: Reactome:R-HSA-5610741 "PKA phosphorylates GLI1" +xref: Reactome:R-HSA-5617179 "PRKACA phosphorylates TNNI3" +xref: Reactome:R-HSA-5617182 "PRKACA phosphorylates PLN" +xref: Reactome:R-HSA-5687088 "PKA phosphorylates MAPKAPK5" +xref: Reactome:R-HSA-913451 "IL3RB is phosphorylated on Ser-585" +is_a: GO:0004690 ! cyclic nucleotide-dependent protein kinase activity +relationship: has_part GO:0030552 ! cAMP binding + +[Term] +id: GO:0004692 +name: cGMP-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP." [GOC:mah] +synonym: "3':5'-cyclic GMP-dependent protein kinase activity" EXACT [EC:2.7.11.12] +synonym: "ATP:protein phosphotransferase (cGMP-dependent) activity" EXACT [EC:2.7.11.12] +synonym: "cGMP-dependent protein kinase ibeta activity" EXACT [EC:2.7.11.12] +synonym: "guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity" EXACT [EC:2.7.11.12] +synonym: "PKG" RELATED [EC:2.7.11.12] +synonym: "PKG 1alpha" RELATED [EC:2.7.11.12] +synonym: "PKG 1beta" RELATED [EC:2.7.11.12] +synonym: "PKG II" RELATED [EC:2.7.11.12] +synonym: "STK23" RELATED [EC:2.7.11.12] +xref: EC:2.7.11.12 +xref: MetaCyc:2.7.11.12-RXN +xref: Reactome:R-HSA-1475422 "PTPS is phosphorylated by cGMP-dependant protein kinase II" +xref: Reactome:R-HSA-1497853 "Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II" +xref: Reactome:R-HSA-418442 "PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release" +xref: Reactome:R-HSA-418549 "PKG1 phosphorylates BK channels" +is_a: GO:0004690 ! cyclic nucleotide-dependent protein kinase activity +relationship: has_part GO:0030553 ! cGMP binding + +[Term] +id: GO:0004693 +name: cyclin-dependent protein serine/threonine kinase activity +namespace: molecular_function +alt_id: GO:0016537 +def: "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)." [GOC:pr, GOC:rn, PMID:7877684, PMID:9841670] +synonym: "ATP:cyclin phosphotransferase activity" EXACT [EC:2.7.11.22] +synonym: "cdc2 kinase activity" NARROW [EC:2.7.11.22] +synonym: "CDK" RELATED [EC:2.7.11.22] +synonym: "CDK activity" EXACT [] +synonym: "CDK, catalytic subunit activity" EXACT [] +synonym: "cdk-activating kinase activity" RELATED [EC:2.7.11.22] +synonym: "Cdk-activating protein kinase activity" EXACT [EC:2.7.11.22] +synonym: "cyclin D-cdk6 kinase activity" NARROW [EC:2.7.11.22] +synonym: "cyclin D-dependent kinase activity" NARROW [EC:2.7.11.22] +synonym: "cyclin E kinase activity" NARROW [EC:2.7.11.22] +synonym: "cyclin-A associated kinase activity" NARROW [EC:2.7.11.22] +synonym: "cyclin-dependent kinase 6 activity" NARROW [EC:2.7.11.22] +synonym: "cyclin-dependent kinase activity" BROAD [EC:2.7.11.22] +synonym: "cyclin-dependent kinase-2 activity" NARROW [EC:2.7.11.22] +synonym: "cyclin-dependent kinase-4 activity" NARROW [EC:2.7.11.22] +synonym: "cyclin-dependent protein kinase activity" BROAD [] +synonym: "cyclin-dependent protein kinase, intrinsic catalyst activity" EXACT [] +synonym: "D-type cyclin kinase activity" NARROW [EC:2.7.11.22] +synonym: "neuronal cdc2-like kinase activity" NARROW [EC:2.7.11.22] +xref: EC:2.7.11.22 +xref: MetaCyc:2.7.11.22-RXN +xref: Reactome:R-HSA-1226094 "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex" +xref: Reactome:R-HSA-1226095 "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex" +xref: Reactome:R-HSA-174079 "Phosphorylation of Cdh1 by Cyclin A:Cdk2" +xref: Reactome:R-HSA-174122 "Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2" +xref: Reactome:R-HSA-174132 "Free APC/C phosphorylated by Cyclin B:Cdc2" +xref: Reactome:R-HSA-174251 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2" +xref: Reactome:R-HSA-180047 "CDK5 phosphorylates DARPP-32 on Thr75" +xref: Reactome:R-HSA-187520 "Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21" +xref: Reactome:R-HSA-187916 "Cyclin A:Cdk2 mediated phosphorylation of p27/p21" +xref: Reactome:R-HSA-187948 "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2" +xref: Reactome:R-HSA-187959 "Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)" +xref: Reactome:R-HSA-188390 "Cyclin E:Cdk2-mediated phosphorylation of Rb" +xref: Reactome:R-HSA-1912391 "NICD1 is phosphorylated by CDK8" +xref: Reactome:R-HSA-2172183 "Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB" +xref: Reactome:R-HSA-2220971 "CDK8 phosphorylates NICD1 PEST domain mutants" +xref: Reactome:R-HSA-2245218 "CDK1 phosphorylates PHF8" +xref: Reactome:R-HSA-2294600 "CDK1 phosphorylates condensin II subunit NCAPD3" +xref: Reactome:R-HSA-2430533 "CDK1 phosphorylates MASTL" +xref: Reactome:R-HSA-2468287 "CDK1 phosphorylates CDCA5 (Sororin) at centromeres" +xref: Reactome:R-HSA-2468293 "CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms" +xref: Reactome:R-HSA-2514854 "CDK1 phosphorylates condensin I" +xref: Reactome:R-HSA-2984220 "CDK1:CCNB phosphorylates NEK9" +xref: Reactome:R-HSA-2990882 "CDK1 phosphorylates NUP98" +xref: Reactome:R-HSA-3788705 "CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2" +xref: Reactome:R-HSA-380278 "CCNB1:p-T160-CDK1 phosphorylates NUMA1" +xref: Reactome:R-HSA-4086410 "CDK1 phosphorylates BORA" +xref: Reactome:R-HSA-4088024 "CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1" +xref: Reactome:R-HSA-5195402 "CDK1 phosphorylates LPIN" +xref: Reactome:R-HSA-5244669 "CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments" +xref: Reactome:R-HSA-5692755 "CDK1 phosphorylates MAPK6" +xref: Reactome:R-HSA-6793661 "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218" +xref: Reactome:R-HSA-6797606 "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes" +xref: Reactome:R-HSA-6805109 "CDK2 phosphorylates TP53" +xref: Reactome:R-HSA-68944 "Orc1 is phosphorylated by cyclin A/CDK2" +xref: Reactome:R-HSA-69005 "Cdc6 protein is phosphorylated by CDK" +xref: Reactome:R-HSA-69227 "Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes" +xref: Reactome:R-HSA-69754 "Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes" +xref: Reactome:R-HSA-69756 "Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes" +xref: Reactome:R-HSA-9008412 "CDK4 phosphorylates RUNX2" +xref: Reactome:R-HSA-9009282 "CDK1 phosphorylates RUNX2" +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0097472 ! cyclin-dependent protein kinase activity + +[Term] +id: GO:0004694 +name: eukaryotic translation initiation factor 2alpha kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate." [GOC:mah, InterPro:IPR015516] +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0045182 ! translation regulator activity +relationship: part_of GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation + +[Term] +id: GO:0004697 +name: protein kinase C activity +namespace: molecular_function +alt_id: GO:0004701 +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol." [EC:2.7.11.13] +synonym: "ATP:protein phosphotransferase (diacylglycerol-dependent) activity" EXACT [EC:2.7.11.13] +synonym: "cPKC" RELATED [EC:2.7.11.13] +synonym: "cPKCalpha" RELATED [EC:2.7.11.13] +synonym: "cPKCbeta" RELATED [EC:2.7.11.13] +synonym: "cPKCgamma" RELATED [EC:2.7.11.13] +synonym: "diacylglycerol-activated phospholipid-dependent PKC activity" EXACT [] +synonym: "diacylglycerol-activated phospholipid-dependent protein kinase C activity" EXACT [] +synonym: "nPKC" RELATED [EC:2.7.11.13] +synonym: "nPKCdelta" RELATED [EC:2.7.11.13] +synonym: "nPKCepsilon" RELATED [EC:2.7.11.13] +synonym: "nPKCeta" RELATED [EC:2.7.11.13] +synonym: "nPKCtheta" RELATED [EC:2.7.11.13] +synonym: "PKC" RELATED [EC:2.7.11.13] +synonym: "PKC activity" EXACT [] +synonym: "Pkc1p" RELATED [EC:2.7.11.13] +synonym: "PKCalpha" RELATED [EC:2.7.11.13] +synonym: "PKCbeta" RELATED [EC:2.7.11.13] +synonym: "PKCdelta" RELATED [EC:2.7.11.13] +synonym: "PKCepsilon" RELATED [EC:2.7.11.13] +synonym: "PKCgamma" RELATED [EC:2.7.11.13] +synonym: "PKCzeta" RELATED [EC:2.7.11.13] +synonym: "protein kinase Cepsilon activity" NARROW [EC:2.7.11.13] +synonym: "STK24" RELATED [EC:2.7.11.13] +xref: EC:2.7.11.13 +xref: MetaCyc:2.7.11.13-RXN +xref: Reactome:R-HSA-1433508 "PKC alpha interacts with and phosphorylates KIT" +xref: Reactome:R-HSA-193703 "IKKbeta is activated" +xref: Reactome:R-HSA-198314 "DAG stimulates protein kinase C-delta" +xref: Reactome:R-HSA-2179413 "Activated PKC-alpha activate MMP3" +xref: Reactome:R-HSA-2730863 "Phosphorylation of CARMA1 by PKC-theta" +xref: Reactome:R-HSA-374664 "Phosphorylation and activation of Ezrin" +xref: Reactome:R-HSA-429698 "PRKD1,2,3 phosphorylates COL4A3BP-2" +xref: Reactome:R-HSA-450533 "PKCdelta phosphorylates HuR" +xref: Reactome:R-HSA-450550 "PKCalpha phosphorylates HuR" +xref: Reactome:R-HSA-5138432 "DVL2 is phosphorylated by PKC" +xref: Reactome:R-HSA-5218805 "PKC autophosphorylates" +xref: Reactome:R-HSA-5218823 "PKC phosphorylates sphingosine kinase 1" +xref: Reactome:R-HSA-5229194 "Depolymerization of lamin filaments after PKC-mediated phosphorylation" +xref: Reactome:R-HSA-5623667 "PDPK1 phosphorylates PKN1,2,3" +xref: Reactome:R-HSA-5625784 "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters" +xref: Reactome:R-HSA-5671749 "p-T774-PKN1 phosphorylates CDC25C" +xref: Reactome:R-HSA-74615 "PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP" +xref: Reactome:R-HSA-751040 "PKC phosphorylates G alpha (z)" +xref: Reactome:R-HSA-8934446 "Activated PKC phosphorylates SHC1" +xref: Reactome:R-HSA-9010681 "PKC phosphorylates ROBO3.1" +xref: Reactome:R-HSA-9021357 "PRKCI phosphorylates ELF3" +xref: Reactome:R-HSA-909552 "Phosphorylation of STAT1 at Ser727" +xref: Reactome:R-HSA-927889 "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)" +xref: Reactome:R-HSA-9626817 "PKC phosphorylates NCF1" +xref: Reactome:R-HSA-9632858 "PRKCZ autophosphorylates downstream of estrogen stimulation" +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004698 +name: calcium-dependent protein kinase C activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol and calcium." [EC:2.7.11.13, GOC:mah] +synonym: "calcium-dependent PKC activity" EXACT [] +synonym: "conventional protein kinase C activity" EXACT [PMID:9601053] +xref: EC:2.7.11.13 +xref: Reactome:R-HSA-114683 "Phosphorylation of Platelet Sec-1" +xref: Reactome:R-HSA-114684 "Phosphorylation of Syntaxin-4" +xref: Reactome:R-HSA-416639 "Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites" +xref: Reactome:R-HSA-421007 "Endocytosis of Ca impermeable AMPA receptors" +is_a: GO:0004697 ! protein kinase C activity +is_a: GO:0009931 ! calcium-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0004699 +name: calcium-independent protein kinase C activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium." [EC:2.7.11.13, GOC:mah] +synonym: "calcium-independent PKC activity" EXACT [] +synonym: "novel protein kinase C activity" EXACT [PMID:9601053] +xref: Reactome:R-HSA-5607740 "PKC-delta phosphorylates CARD9" +is_a: GO:0004697 ! protein kinase C activity + +[Term] +id: GO:0004702 +name: obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity +namespace: molecular_function +def: "OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [EC:2.7.11.13, GOC:bf, GOC:mah] +comment: This term was obsoleted because it was not clearly defined. +synonym: "receptor signaling protein serine/threonine kinase activity" EXACT [] +synonym: "receptor signalling protein serine/threonine kinase activity" EXACT [] +xref: EC:2.7.11 +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0004703 +name: G protein-coupled receptor kinase activity +namespace: molecular_function +alt_id: GO:0004678 +def: "Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate." [GOC:dph] +synonym: "ATP:G-protein-coupled receptor phosphotransferase activity" EXACT [EC:2.7.11.16] +synonym: "G protein coupled receptor phosphorylating protein kinase activity" EXACT [] +synonym: "G protein-coupled receptor kinase activity" EXACT [EC:2.7.11.16] +synonym: "G-protein coupled receptor kinase activity" EXACT [EC:2.7.11.16] +synonym: "G-protein-coupled receptor phosphorylating protein kinase activity" EXACT [] +synonym: "GPCR kinase activity" EXACT [EC:2.7.11.16] +synonym: "GPCR phosphorylating protein kinase activity" EXACT [] +synonym: "GPCRK" RELATED [EC:2.7.11.16] +synonym: "GRK4" RELATED [EC:2.7.11.16] +synonym: "GRK5" RELATED [EC:2.7.11.16] +synonym: "GRK6" RELATED [EC:2.7.11.16] +synonym: "STK16" RELATED [EC:2.7.11.16] +xref: EC:2.7.11.16 +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004704 +name: NF-kappaB-inducing kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK)." [PMID:20685151] +synonym: "NIK" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0038061 ! NIK/NF-kappaB signaling + +[Term] +id: GO:0004705 +name: JUN kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors." [GOC:bf, ISBN:0198506732] +synonym: "c-Jun N-terminal kinase activity" NARROW [] +synonym: "JNK" EXACT [] +synonym: "JNK3alpha1" RELATED [] +synonym: "SAPK1" NARROW [] +xref: Reactome:R-HSA-168136 "Activated JNKs phosphorylate c-JUN" +xref: Reactome:R-HSA-204949 "NRIF and TRAF6 may activate JNK" +xref: Reactome:R-HSA-205075 "JNK phosphorylates BIM, BAD and other targets" +xref: Reactome:R-HSA-205132 "NRAGE activates JNK" +is_a: GO:0004707 ! MAP kinase activity +relationship: part_of GO:0007258 ! JUN phosphorylation + +[Term] +id: GO:0004706 +name: JUN kinase kinase kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs)." [GOC:bf] +synonym: "JNK kinase kinase activity" RELATED [] +synonym: "JNKKK" EXACT [] +is_a: GO:0004709 ! MAP kinase kinase kinase activity +relationship: part_of GO:0007256 ! activation of JNKK activity + +[Term] +id: GO:0004707 +name: MAP kinase activity +namespace: molecular_function +alt_id: GO:0008338 +alt_id: GO:0008339 +alt_id: GO:0016908 +alt_id: GO:0016909 +def: "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684] +synonym: "ATP:protein phosphotransferase (MAPKK-activated) activity" EXACT [EC:2.7.11.24] +synonym: "ERK" RELATED [EC:2.7.11.24] +synonym: "ERK1" EXACT [] +synonym: "ERK2" RELATED [] +synonym: "extracellular signal-regulated kinase activity" NARROW [EC:2.7.11.24] +synonym: "MAP kinase 1 activity" NARROW [] +synonym: "MAP kinase 2 activity" NARROW [] +synonym: "MAPK" RELATED [EC:2.7.11.24, PMID:20811974] +synonym: "MBP kinase I activity" NARROW [EC:2.7.11.24] +synonym: "MBP kinase II activity" NARROW [EC:2.7.11.24] +synonym: "mitogen activated kinase activity" EXACT [] +synonym: "mitogen-activated protein kinase activity" EXACT [EC:2.7.11.24] +synonym: "myelin basic protein kinase activity" NARROW [EC:2.7.11.24] +synonym: "SAP kinase activity" NARROW [] +synonym: "SAPK" NARROW [] +synonym: "stress-activated kinase activity" NARROW [] +synonym: "stress-activated protein kinase activity" NARROW [] +xref: EC:2.7.11.24 +xref: KEGG_REACTION:R00162 +xref: MetaCyc:2.7.11.24-RXN +xref: Reactome:R-HSA-111898 "Phosphorylation of cPLA2 by ERK-2" +xref: Reactome:R-HSA-198733 "ERK5 is activated" +xref: Reactome:R-HSA-445079 "Phosphorylation of L1 by ERK" +xref: Reactome:R-HSA-451366 "Activation of p38MAPK by DSCAM" +xref: Reactome:R-HSA-5654560 "Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2." +xref: Reactome:R-HSA-5654562 "Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2" +xref: Reactome:R-HSA-5654565 "Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2." +xref: Reactome:R-HSA-5654566 "Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2." +xref: Reactome:R-HSA-73722 "Phosphorylation of UBF-1:rDNA Promoter" +xref: Reactome:R-HSA-9626832 "MAPK1 or MAPK3 phosphorylates NCF1 at Ser345" +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: part_of GO:0000165 ! MAPK cascade + +[Term] +id: GO:0004708 +name: MAP kinase kinase activity +namespace: molecular_function +def: "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate." [ISBN:0198547684] +synonym: "ATP:protein phosphotransferase (MAPKKK-activated) activity" EXACT [EC:2.7.12.2] +synonym: "ERK activator kinase activity" EXACT [] +synonym: "MAP kinase kinase 4 activity" NARROW [EC:2.7.12.2] +synonym: "MAP kinase kinase 7 activity" NARROW [EC:2.7.12.2] +synonym: "MAP kinase or ERK kinase activity" RELATED [EC:2.7.12.2] +synonym: "MAP2K" RELATED [EC:2.7.12.2] +synonym: "MAPK activator activity" EXACT [GOC:vw] +synonym: "MAPKK" RELATED [EC:2.7.12.2, PMID:20811974] +synonym: "MAPKK activity" EXACT [] +synonym: "MAPKK1" RELATED [EC:2.7.12.2] +synonym: "MEK activity" BROAD [] +synonym: "MEK1" RELATED [EC:2.7.12.2] +synonym: "MEK2" RELATED [EC:2.7.12.2] +synonym: "mitogen-activated protein kinase kinase activity" EXACT [EC:2.7.12.2] +synonym: "MKK" RELATED [EC:2.7.12.2] +synonym: "MKK2" RELATED [EC:2.7.12.2] +synonym: "MKK4" RELATED [EC:2.7.12.2] +synonym: "MKK6" RELATED [EC:2.7.12.2] +synonym: "MKK7" RELATED [EC:2.7.12.2] +synonym: "STK27" RELATED [EC:2.7.12.2] +xref: EC:2.7.12.2 +xref: MetaCyc:2.7.12.2-RXN +xref: Reactome:R-HSA-1247960 "Activation of p38 MAPK" +xref: Reactome:R-HSA-3238999 "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5" +xref: Reactome:R-HSA-448951 "Activation of p38 alpha/beta MAPK" +xref: Reactome:R-HSA-450333 "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3" +xref: Reactome:R-HSA-5218804 "p38 MAPK activation by VEGFR" +is_a: GO:0004712 ! protein serine/threonine/tyrosine kinase activity +relationship: part_of GO:0000165 ! MAPK cascade +relationship: part_of GO:0000187 ! activation of MAPK activity + +[Term] +id: GO:0004709 +name: MAP kinase kinase kinase activity +namespace: molecular_function +alt_id: GO:0004710 +def: "Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases." [PMID:9561267] +synonym: "ATP:protein phosphotransferase (MAPKKKK-activated) activity" EXACT [EC:2.7.11.25] +synonym: "cMos" RELATED [EC:2.7.11.25] +synonym: "cRaf" RELATED [EC:2.7.11.25] +synonym: "MAP3K" RELATED [EC:2.7.11.25, PMID:20811974] +synonym: "MAPK/ERK kinase kinase activity" EXACT [] +synonym: "MAPKKK activity" EXACT [EC:2.7.11.25] +synonym: "MEK kinase activity" EXACT [EC:2.7.11.25] +synonym: "MEKK" RELATED [EC:2.7.11.25] +synonym: "MEKK activity" EXACT [] +synonym: "MEKK1" RELATED [EC:2.7.11.25] +synonym: "MEKK2" RELATED [EC:2.7.11.25] +synonym: "MEKK3" RELATED [EC:2.7.11.25] +synonym: "Mil/Raf" RELATED [EC:2.7.11.25] +synonym: "mitogen-activated protein kinase kinase kinase activity" EXACT [EC:2.7.11.25] +synonym: "MLK-like mitogen-activated protein triple kinase activity" NARROW [EC:2.7.11.25] +synonym: "MLTK" RELATED [EC:2.7.11.25] +synonym: "MLTKa" RELATED [EC:2.7.11.25] +synonym: "MLTKb" RELATED [EC:2.7.11.25] +synonym: "REKS" RELATED [EC:2.7.11.25] +synonym: "STK28" RELATED [EC:2.7.11.25] +xref: EC:2.7.11.25 +xref: MetaCyc:2.7.11.25-RXN +xref: Reactome:R-HSA-168184 "Activated TAK1 mediates phosphorylation of the IKK Complex" +xref: Reactome:R-HSA-2730887 "Autophosphorylation and activation of MEKK1" +xref: Reactome:R-HSA-392530 "p-S400-Cot phosphorylates NIK" +xref: Reactome:R-HSA-450337 "Activated TAK1 phosphorylates MKK4/MKK7" +xref: Reactome:R-HSA-450346 "activated human TAK1 phosphorylates MKK3/MKK6" +xref: Reactome:R-HSA-451649 "TPL2 phosphorylates MEK1, SEK1" +xref: Reactome:R-HSA-727819 "TAK1 phosphorylates MKK6" +xref: Reactome:R-HSA-933530 "Activation of IKK by MEKK1" +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: part_of GO:0000165 ! MAPK cascade +relationship: part_of GO:0000186 ! activation of MAPKK activity + +[Term] +id: GO:0004711 +name: ribosomal protein S6 kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP." [GOC:mah, PMID:9822608] +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0004712 +name: protein serine/threonine/tyrosine kinase activity +namespace: molecular_function +def: "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate." [GOC:mah] +synonym: "ADK1" RELATED [EC:2.7.12.1] +synonym: "Arabidopsis dual specificity kinase 1 activity" NARROW [EC:2.7.12.1] +synonym: "ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating) activity" EXACT [EC:2.7.12.1] +synonym: "CLK1" RELATED [EC:2.7.12.1] +synonym: "dDYRK2" RELATED [EC:2.7.12.1] +synonym: "dual-specificity kinase activity" BROAD [EC:2.7.12.1] +synonym: "dual-specificity protein kinase" BROAD [] +synonym: "Mps1p" RELATED [EC:2.7.12.1] +synonym: "protein threonine/tyrosine kinase activity" NARROW [] +xref: EC:2.7.12.1 +xref: Reactome:R-HSA-5672969 "Phosphorylation of RAF" +xref: Reactome:R-HSA-5674373 "MAP2Ks phosphorylate MAPK at the Golgi membrane" +xref: Reactome:R-HSA-6802910 "Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants" +xref: Reactome:R-HSA-6802916 "RAF is phosphorylated downstream of moderate kinase activity BRAF mutants" +xref: Reactome:R-HSA-6802918 "Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants" +xref: Reactome:R-HSA-6802921 "Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants" +xref: Reactome:R-HSA-6802922 "Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS" +xref: Reactome:R-HSA-6802924 "RAF is phosphorylated downstream of oncogenic RAS" +xref: Reactome:R-HSA-6802927 "BRAF and RAF fusion mutant dimers are phosphorylated" +xref: Reactome:R-HSA-6802941 "RAF is paradoxically phosphorylated downstream of kinase-inactive RAF" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0004713 +name: protein tyrosine kinase activity +namespace: molecular_function +alt_id: GO:0004718 +def: "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate." [EC:2.7.10] +synonym: "JAK" NARROW [] +synonym: "Janus kinase activity" NARROW [] +synonym: "protein-tyrosine kinase activity" EXACT [] +xref: EC:2.7.10 +xref: Reactome:R-HSA-112333 "SRC autophosphorylation is positively regulated by InlA-bound CDH1" +xref: Reactome:R-HSA-114600 "Fyn/Lyn-mediated phosphorylation of FcR1 gamma" +xref: Reactome:R-HSA-1168394 "STAT5 tyrosine phosphorylation" +xref: Reactome:R-HSA-1169421 "Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers" +xref: Reactome:R-HSA-1225952 "Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants" +xref: Reactome:R-HSA-1225960 "Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants" +xref: Reactome:R-HSA-1247844 "Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants" +xref: Reactome:R-HSA-1248655 "Trans-autophosphorylation of EGFRvIII mutant dimers" +xref: Reactome:R-HSA-1250195 "SHC1 phosphorylation by ERBB2 heterodimers" +xref: Reactome:R-HSA-1250315 "Trans-autophosphorylation of ERBB4 homodimers" +xref: Reactome:R-HSA-1250348 "Phosphorylation of SHC1 by ERBB4 homodimers" +xref: Reactome:R-HSA-1251922 "PLCG1 phosphorylation by p-EGFR:p-ERBB2" +xref: Reactome:R-HSA-1295540 "IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5" +xref: Reactome:R-HSA-1295609 "SRC phosphorylates SPRY2 on Y55 and Y227" +xref: Reactome:R-HSA-1307963 "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4" +xref: Reactome:R-HSA-1433418 "Phosphorylation of JAK2" +xref: Reactome:R-HSA-1433454 "Phosphorylation of GAB2 by SFKs" +xref: Reactome:R-HSA-1433488 "Phosphorylation of SHP2 by SFKs" +xref: Reactome:R-HSA-1433506 "Phosphorylation of APS" +xref: Reactome:R-HSA-1433542 "Phosphorylation and activation of VAV1" +xref: Reactome:R-HSA-1470009 "Phosphorylation of STATs" +xref: Reactome:R-HSA-1524186 "Phosphorylation of PLCgamma by PDGFR" +xref: Reactome:R-HSA-1671691 "PRLR-bound STAT5 is phosphorylated" +xref: Reactome:R-HSA-170070 "Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes" +xref: Reactome:R-HSA-170156 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes" +xref: Reactome:R-HSA-170991 "SRC-1 autophosphorylates" +xref: Reactome:R-HSA-171011 "Binding and activation of MAP Kinase" +xref: Reactome:R-HSA-174164 "Phosphorylation of Cyclin A:Cdk2 at Tyr 15" +xref: Reactome:R-HSA-177930 "GAB1 phosphorylation by EGFR kinase" +xref: Reactome:R-HSA-177934 "EGFR autophosphorylation" +xref: Reactome:R-HSA-177937 "Phosphorylation of EGFR by SRC kinase" +xref: Reactome:R-HSA-182969 "Phosphorylation of CBL (EGFR:CBL)" +xref: Reactome:R-HSA-183058 "Phosphorylation of CBL (EGFR:GRB2:CBL)" +xref: Reactome:R-HSA-1839065 "Phosphorylation of cytosolic FGFR1 fusion dimers" +xref: Reactome:R-HSA-1839067 "Phosphorylation of BCR moiety of BCR-FGFR1" +xref: Reactome:R-HSA-1839098 "Activated FGFR1 mutants and fusions phosphorylate PLCG1" +xref: Reactome:R-HSA-1839110 "p-BCR-p-FGFR1 phosphorylates GAB2" +xref: Reactome:R-HSA-1839112 "Phosphorylation of STAT5 by cytosolic FGFR1 fusions" +xref: Reactome:R-HSA-186786 "Autophosphorylation of PDGF beta receptors" +xref: Reactome:R-HSA-1888198 "FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3" +xref: Reactome:R-HSA-190326 "Autocatalytic phosphorylation of FGFR4" +xref: Reactome:R-HSA-190385 "Autocatalytic phosphorylation of FGFR3b" +xref: Reactome:R-HSA-190388 "Autocatalytic phosphorylation of FGFR3c" +xref: Reactome:R-HSA-190408 "Autocatalytic phosphorylation of FGFR2b" +xref: Reactome:R-HSA-190413 "Autocatalytic phosphorylation of FGFR2c" +xref: Reactome:R-HSA-190427 "Autocatalytic phosphorylation of FGFR1b" +xref: Reactome:R-HSA-190429 "Autocatalytic phosphorylation of FGFR1c" +xref: Reactome:R-HSA-191062 "Autocatalytic phosphorylation of Klotho-bound FGFR1c" +xref: Reactome:R-HSA-191636 "Phosphorylation of Cx43 by c-src" +xref: Reactome:R-HSA-1963581 "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers" +xref: Reactome:R-HSA-1963582 "Trans-autophosphorylation of ERBB2 heterodimers" +xref: Reactome:R-HSA-1963586 "SRC family kinases phosphorylate ERBB2" +xref: Reactome:R-HSA-1982066 "Ligand-independent phosphorylation of overexpressed FGFR1" +xref: Reactome:R-HSA-2012073 "Autocatalytic phosphorylation of FGFR3c P250R mutant" +xref: Reactome:R-HSA-2012082 "Autocatalytic phosphorylation of FGFR3 cysteine mutants" +xref: Reactome:R-HSA-2012087 "Autocatalytic phosphorylation of FGFR4 Y367C mutant" +xref: Reactome:R-HSA-202165 "Phosphorylation of ITAM motifs in CD3 complexes" +xref: Reactome:R-HSA-202168 "Phosphorylation of ZAP-70 by Lck" +xref: Reactome:R-HSA-202174 "Activation of ZAP-70" +xref: Reactome:R-HSA-202216 "Phosphorylation of SLP-76" +xref: Reactome:R-HSA-202233 "Inactivation of Lck by Csk" +xref: Reactome:R-HSA-202245 "Phosphorylation of TBSMs in LAT" +xref: Reactome:R-HSA-202248 "Phosphorylation of PLC-gamma1" +xref: Reactome:R-HSA-202291 "Activation of Lck" +xref: Reactome:R-HSA-202307 "Change of PKC theta conformation" +xref: Reactome:R-HSA-2023455 "Autocatalytic phosphorylation of FGFR1c P252X mutant dimers" +xref: Reactome:R-HSA-2023460 "Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity" +xref: Reactome:R-HSA-2029268 "Phosphorylation and activation of PLCG" +xref: Reactome:R-HSA-2029449 "Phosphorylation of SYK by Src kinases" +xref: Reactome:R-HSA-2029453 "Phosphorylation of VAV" +xref: Reactome:R-HSA-2029459 "Sequestering and phosphorylation Fc gamma receptors in the lipid rafts" +xref: Reactome:R-HSA-2029984 "Autocatalytic phosphorylation of FGFR2 ligand-independent mutants" +xref: Reactome:R-HSA-2029989 "Autocatalytic phosphorylation of overexpressed FGFR2 variants" +xref: Reactome:R-HSA-2033485 "Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity" +xref: Reactome:R-HSA-2033486 "Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding" +xref: Reactome:R-HSA-2033488 "Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding" +xref: Reactome:R-HSA-2033490 "Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity" +xref: Reactome:R-HSA-2038387 "Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants" +xref: Reactome:R-HSA-2038944 "Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity" +xref: Reactome:R-HSA-205289 "Autophosphorylation of KIT" +xref: Reactome:R-HSA-210291 "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src" +xref: Reactome:R-HSA-210872 "Trans-phosphorylation of Tie2" +xref: Reactome:R-HSA-212710 "EGFR activates PLC-gamma1 by phosphorylation" +xref: Reactome:R-HSA-2130194 "ABL phosphorylates WAVEs" +xref: Reactome:R-HSA-2197698 "Phosphorylation of WASP/N-WASP" +xref: Reactome:R-HSA-2201322 "TIRAP is phosphorylated by BTK" +xref: Reactome:R-HSA-2395412 "Phosphorylation of SYK" +xref: Reactome:R-HSA-2395439 "Phosphorylation of DAP12" +xref: Reactome:R-HSA-2395801 "Phosphorylation of LAT by p-SYK" +xref: Reactome:R-HSA-2396594 "Phosphorylation of SLP-76 by p-SYK" +xref: Reactome:R-HSA-2404193 "IGF1R phosphorylates SHC1" +xref: Reactome:R-HSA-2404199 "IGF1,2:IGF1R autophosphorylates" +xref: Reactome:R-HSA-2424484 "Phosphorylation of BTK by p-SYK" +xref: Reactome:R-HSA-2424486 "Phosphorylation and activation of VAV2/VAV3 by SYK" +xref: Reactome:R-HSA-2424487 "Phosphorylation of PLC-gamma by p-BTK/p-SYK" +xref: Reactome:R-HSA-2428926 "IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4" +xref: Reactome:R-HSA-2454208 "Phosphorylation of beta and gamma subunits by LYN" +xref: Reactome:R-HSA-2454239 "Phosphorylation of SYK" +xref: Reactome:R-HSA-2586553 "JAK2 Phosphorylates LEPR" +xref: Reactome:R-HSA-2586555 "JAK2 Autophosphorylates in Response to Leptin" +xref: Reactome:R-HSA-2671742 "JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin" +xref: Reactome:R-HSA-2671829 "JAK2 Phosphorylates STAT5 in Response to Leptin" +xref: Reactome:R-HSA-2671850 "JAK2 Phosphoryates STAT3 in Response to Leptin" +xref: Reactome:R-HSA-2730833 "Phosphorylation of TEC kinases by p-SYK" +xref: Reactome:R-HSA-2730843 "Phosphorylation of LAT by p-SYK" +xref: Reactome:R-HSA-2730851 "Phosphorylation of SLP-76 by p-SYK" +xref: Reactome:R-HSA-2730858 "Autophosphorylation of BTK/ITK" +xref: Reactome:R-HSA-2730860 "Phosphorylation of GAB2 by SYK/FYN" +xref: Reactome:R-HSA-2730862 "Autophosphorylation of LYN kinase" +xref: Reactome:R-HSA-2730882 "Phosphorylation of PKC-theta" +xref: Reactome:R-HSA-2730884 "Phosphorylation of NTAL by p-SYK/Lyn" +xref: Reactome:R-HSA-2730886 "Phosphorylation of SHC by SYK kinase" +xref: Reactome:R-HSA-2730888 "Phosphorylation of PLC-gamma" +xref: Reactome:R-HSA-3215391 "PRMT5 is tyrosine phosphorylated by JAK2 V617F" +xref: Reactome:R-HSA-354073 "Autophosphorylation of PTK2 at Y397" +xref: Reactome:R-HSA-354124 "Phosphorylation of pPTK2 by SRC" +xref: Reactome:R-HSA-372693 "Phosphorylation of BCAR1 by SRC-PTK2 complex" +xref: Reactome:R-HSA-373747 "Phosphorylation of nephrin by FYN" +xref: Reactome:R-HSA-373750 "SEMA4D interacts with Plexin-B1:ErbB2" +xref: Reactome:R-HSA-374701 "Phosphorylation of DCC by Fyn" +xref: Reactome:R-HSA-377640 "Autophosphorylation of SRC" +xref: Reactome:R-HSA-380780 "Activation of Src" +xref: Reactome:R-HSA-388831 "Phosphorylation of CD28" +xref: Reactome:R-HSA-388833 "Phosphorylation of CTLA-4" +xref: Reactome:R-HSA-389083 "Autophosphorylation of PDGF alpha receptors" +xref: Reactome:R-HSA-389086 "Autophosphorylation of PDGF alpha/beta receptors" +xref: Reactome:R-HSA-389354 "Activation of Vav1" +xref: Reactome:R-HSA-389762 "Phosphorylation of PD-1" +xref: Reactome:R-HSA-391156 "Phosphorylation of ITIM motif in SIRP alpha" +xref: Reactome:R-HSA-391865 "Recruitment of FAK to NCAM1:Fyn in lipid rafts" +xref: Reactome:R-HSA-391866 "Phosphorylation of FAK by Src kinase" +xref: Reactome:R-HSA-391871 "Autophosphorylation of NCAM1 bound Fyn" +xref: Reactome:R-HSA-3928578 "EPH receptors autophosphorylate" +xref: Reactome:R-HSA-3928580 "SFKs phosphorylate EFNBs" +xref: Reactome:R-HSA-3928583 "FYN phosphorylates NMDAR2B" +xref: Reactome:R-HSA-3928594 "SFKs phosphorylate GIT1" +xref: Reactome:R-HSA-3928604 "SFKs phosphorylate VAV2,3" +xref: Reactome:R-HSA-3928610 "PTK2 autophosphorylates at Y397" +xref: Reactome:R-HSA-3928627 "EPHB phosphorylates TIAM1" +xref: Reactome:R-HSA-3928648 "SFKs phosphorylate NGEF" +xref: Reactome:R-HSA-399934 "Phosphorylation of Plexin-A" +xref: Reactome:R-HSA-399946 "Recruitment and activation of Cdk5" +xref: Reactome:R-HSA-399947 "Tyrosine phosphorylation of CRMPs by Fes" +xref: Reactome:R-HSA-4093332 "p-EPHB phosphorylates SDC2" +xref: Reactome:R-HSA-418163 "Activated Src activates ERK" +xref: Reactome:R-HSA-418859 "Phosphorylation of Unc5C" +xref: Reactome:R-HSA-418872 "Phosphorylation of FADK1" +xref: Reactome:R-HSA-419646 "SEMA4D interacts with Plexin-B1:Met" +xref: Reactome:R-HSA-428888 "Phosphorylation of ROBO1 by ABL kinase" +xref: Reactome:R-HSA-429441 "SYK activation by SRC" +xref: Reactome:R-HSA-429449 "Syk activation leads to SLP-76 activation" +xref: Reactome:R-HSA-432129 "FGR binds and phosphorylates LRP8" +xref: Reactome:R-HSA-434836 "Syk/Lck phosphorylate LAT" +xref: Reactome:R-HSA-4420117 "VEGFR2 autophosphorylates" +xref: Reactome:R-HSA-4420121 "SFKs phosphorylate PLCG1" +xref: Reactome:R-HSA-4420128 "SRC-1 phosphorylates SHB" +xref: Reactome:R-HSA-4420206 "Phosphorylation of SRC-1" +xref: Reactome:R-HSA-443817 "Phosphorylation of L1 by EPHB2" +xref: Reactome:R-HSA-445076 "Phosphorylation of Y1229 in L1" +xref: Reactome:R-HSA-445084 "Phosphorylation of L1 by SRC" +xref: Reactome:R-HSA-445085 "Phosphorylation of VAV2" +xref: Reactome:R-HSA-445091 "Phosphorylation of Neurofascin" +xref: Reactome:R-HSA-451942 "Within the IL-2R complex JAK3 phosphorylates JAK1" +xref: Reactome:R-HSA-452097 "Recruited STAT5 is phosphorylated" +xref: Reactome:R-HSA-452100 "SHC1 bound to IL2 receptor is phosphorylated" +xref: Reactome:R-HSA-452122 "JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB" +xref: Reactome:R-HSA-508282 "SYK is a substrate for JAK1" +xref: Reactome:R-HSA-5218640 "SRC-1 phosphorylates p-Y397-PTK2" +xref: Reactome:R-HSA-5218642 "PTK2 autophosphorylates" +xref: Reactome:R-HSA-5218806 "FYN autophosphorylates" +xref: Reactome:R-HSA-5218809 "PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118" +xref: Reactome:R-HSA-5218812 "FYN phosphorylates PAK2" +xref: Reactome:R-HSA-5218820 "Src kinases phosphorylate VAV" +xref: Reactome:R-HSA-5218828 "PTK2/SRC-1 phosphorylates BCAR1" +xref: Reactome:R-HSA-5218830 "SRC-1 phosphorylates PTK2-beta" +xref: Reactome:R-HSA-5218851 "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407" +xref: Reactome:R-HSA-5357429 "AXL autophosphorylates on Y772 and Y814" +xref: Reactome:R-HSA-5607745 "1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG" +xref: Reactome:R-HSA-5607750 "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan" +xref: Reactome:R-HSA-5621355 "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG" +xref: Reactome:R-HSA-5621363 "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2" +xref: Reactome:R-HSA-5621370 "SYK autophosphorylates" +xref: Reactome:R-HSA-5624486 "SFKs phosphorylates RAF1 on Y340,Y341" +xref: Reactome:R-HSA-5637795 "Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant" +xref: Reactome:R-HSA-5637796 "Phosphorylation of SHC1 by p-5Y-EGFRvIII" +xref: Reactome:R-HSA-5654147 "Activated FGFR2 phosphorylates PLCG1" +xref: Reactome:R-HSA-5654149 "Activated FGFR1 phosphorylates PLCG1" +xref: Reactome:R-HSA-5654151 "Activated FGFR4 phosphorylates PLCG1" +xref: Reactome:R-HSA-5654222 "Activated FGFR3 phosphorylates PLCG1" +xref: Reactome:R-HSA-5654397 "Activated FGFR2 phosphorylates FRS2" +xref: Reactome:R-HSA-5654407 "Activated FGFR2 phosphorylates SHC1" +xref: Reactome:R-HSA-5654408 "Activated FGFR3 phosphorylates FRS2" +xref: Reactome:R-HSA-5654418 "Activated FGFR4 phosphorylates FRS2" +xref: Reactome:R-HSA-5654428 "Activated FGFR4 phosphorylates SHC1" +xref: Reactome:R-HSA-5654545 "Ligand-independent phosphorylation of overexpressed FGFR1c" +xref: Reactome:R-HSA-5654575 "Activated FGFR1 phosphorylates FRS2" +xref: Reactome:R-HSA-5654578 "Activated FGFR1 phosphorylates FRS3" +xref: Reactome:R-HSA-5654582 "Activated FGFR1 phosphorylates SHC1" +xref: Reactome:R-HSA-5654587 "Activated FGFR1:p-FRS phosphorylates PPTN11" +xref: Reactome:R-HSA-5654605 "Activated FGFR2 phosphorylates FRS3" +xref: Reactome:R-HSA-5654607 "Activated FGFR2 phosphorylates PPTN11" +xref: Reactome:R-HSA-5654628 "Activated FGFR3 phosphorylates FRS3" +xref: Reactome:R-HSA-5654631 "Activated FGFR3 phosphorylates PPTN11" +xref: Reactome:R-HSA-5654634 "Activated FGFR3 phosphorylates SHC1" +xref: Reactome:R-HSA-5654653 "Activated FGFR4 phosphorylates FRS3" +xref: Reactome:R-HSA-5654655 "Activated FGFR4 phosphorylates PPTN11" +xref: Reactome:R-HSA-5655243 "Activated FGFR3 mutants phosphorylate PLCG1" +xref: Reactome:R-HSA-5655268 "Activated FGFR2 mutants phosphorylate FRS2" +xref: Reactome:R-HSA-5655270 "Activated FGFR3 mutants phosphorylate FRS2" +xref: Reactome:R-HSA-5655278 "Activated FGFR1 mutants phosphorylate FRS2" +xref: Reactome:R-HSA-5655284 "Activated FGFR4 mutants phosphorylate FRS2" +xref: Reactome:R-HSA-5655301 "Activated FGFR2 mutants phosphorylate PLCG1" +xref: Reactome:R-HSA-5655341 "Activated FGFR4 mutants phosphorylate PLCG1" +xref: Reactome:R-HSA-5683930 "WICH phosphorylates H2AFX on Y142" +xref: Reactome:R-HSA-5686587 "ABL1 phosphorylates RAD52" +xref: Reactome:R-HSA-5690702 "LYN phosphorylates CD22" +xref: Reactome:R-HSA-6784006 "STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2" +xref: Reactome:R-HSA-6784319 "JAK1,TYK2 phosphorylate JAK1,TYK2" +xref: Reactome:R-HSA-6790087 "HVEM induses BTLA phosphorylation" +xref: Reactome:R-HSA-6806974 "MET dimers autophosphorylate" +xref: Reactome:R-HSA-68954 "Mcm2-7 is phosphorylated by DDK" +xref: Reactome:R-HSA-69195 "Phosphorylation of Cyclin E:CDK2 complexes by WEE1" +xref: Reactome:R-HSA-873918 "Transphosphorylation of JAK1" +xref: Reactome:R-HSA-873919 "Phosphorylation of JAK2" +xref: Reactome:R-HSA-873922 "Phosphorylation of STAT1 by JAK kinases" +xref: Reactome:R-HSA-873924 "Phosphorylation of IFNGR1 by JAK kinases" +xref: Reactome:R-HSA-879907 "Tyrosine kinases phosphorylate the receptor" +xref: Reactome:R-HSA-879909 "Activation of STAT5a/b by JAK2" +xref: Reactome:R-HSA-879925 "SHC1 bound to the common beta chain becomes tyrosine phosphorylated" +xref: Reactome:R-HSA-8847977 "FRK phosphorylates PTEN" +xref: Reactome:R-HSA-8848005 "ERBB2 promotes PTK6 autophosphorylation" +xref: Reactome:R-HSA-8848077 "PTK6 phosphorylates STAP2" +xref: Reactome:R-HSA-8848124 "PTK6 phosphorylates STAT3" +xref: Reactome:R-HSA-8848436 "PTK6 phosphorylates CDKN1B" +xref: Reactome:R-HSA-8848606 "PTK6 phosphorylates PXN" +xref: Reactome:R-HSA-8848726 "PTK6 phosphorylates BCAR1" +xref: Reactome:R-HSA-8848758 "PTK6 phosphorylates AKT1" +xref: Reactome:R-HSA-8848776 "PTK6 phosphorylates DOK1" +xref: Reactome:R-HSA-8848818 "PTK6 phosphorylates CBL" +xref: Reactome:R-HSA-8848873 "PTK6 phosphorylates ARAP1" +xref: Reactome:R-HSA-8848975 "PTK6 phosphorylates KHDRBS1" +xref: Reactome:R-HSA-8849032 "PTK6 phosphorylates KHDRBS2" +xref: Reactome:R-HSA-8849042 "PTK6 phosphorylates KHDRBS3" +xref: Reactome:R-HSA-8849068 "PTK6 phosphorylates ARHGAP35" +xref: Reactome:R-HSA-8849102 "SRMS phosphorylates PTK6" +xref: Reactome:R-HSA-8849463 "PTK6 phosphorylates SFPQ" +xref: Reactome:R-HSA-8851890 "MET phosphorylates SHC1-2" +xref: Reactome:R-HSA-8851933 "MET phosphorylates GAB1" +xref: Reactome:R-HSA-8853309 "Autocatalytic phosphorylation of FGFR3 fusions" +xref: Reactome:R-HSA-8853313 "FGFR2 fusions autophosphorylate" +xref: Reactome:R-HSA-8853315 "Activated FGFR3 fusions phosphorylate FRS2" +xref: Reactome:R-HSA-8853325 "Plasma membrane FGFR1 fusions autophosphorylate" +xref: Reactome:R-HSA-8855237 "FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1" +xref: Reactome:R-HSA-8857555 "EGFR phosphorylates GPNMB" +xref: Reactome:R-HSA-8857577 "LINC01139 facilitates PTK6 autophosphorylation" +xref: Reactome:R-HSA-8857583 "LINC01139 promotes phosphorylation of HIF1A by PTK6" +xref: Reactome:R-HSA-8857925 "Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307" +xref: Reactome:R-HSA-8867041 "EGFR phosphorylates EPS15" +xref: Reactome:R-HSA-8874078 "PTK2 autophosphorylates" +xref: Reactome:R-HSA-8874080 "SRC phosphorylates PTK2" +xref: Reactome:R-HSA-8874082 "MET phosphorylates PTK2" +xref: Reactome:R-HSA-8875451 "MET phosphorylates CBL" +xref: Reactome:R-HSA-8875817 "MET phosphorylates STAT3" +xref: Reactome:R-HSA-8876230 "InlB:MET dimer trans-autophophorylates" +xref: Reactome:R-HSA-8876246 "InlB-activated MET phosphorylates CBL" +xref: Reactome:R-HSA-8876948 "SRC phosphorylates InlA-bound CDH1 and CTNNB1" +xref: Reactome:R-HSA-8937728 "SRC phosphorylates RUNX1" +xref: Reactome:R-HSA-8937807 "SRC phosphorylates RUNX3" +xref: Reactome:R-HSA-8937844 "SRC,YES1 phosphorylate YAP1" +xref: Reactome:R-HSA-8942607 "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes" +xref: Reactome:R-HSA-8948143 "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18" +xref: Reactome:R-HSA-8956659 "ABL1 phosphorylates YAP1" +xref: Reactome:R-HSA-8964242 "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC" +xref: Reactome:R-HSA-8964252 "G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC" +xref: Reactome:R-HSA-8983872 "JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4" +xref: Reactome:R-HSA-9006323 "Phospho-JAK2 phosphorylates EPOR" +xref: Reactome:R-HSA-9006332 "JAK2 transphosphorylates and is activated in response to Erythropoietin" +xref: Reactome:R-HSA-9011241 "SRC phosphorylates ROBO3.1 in response to NTN1" +xref: Reactome:R-HSA-9012650 "JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2" +xref: Reactome:R-HSA-9018572 "EGFR phosphorylates NOTCH3" +xref: Reactome:R-HSA-9021609 "ESR-associated SRC autophosphorylates" +xref: Reactome:R-HSA-9024726 "LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1" +xref: Reactome:R-HSA-9026464 "BDNF-bound NTRK2 dimers trans-autophosphorylate" +xref: Reactome:R-HSA-9026502 "NTF3-bound NTRK2 dimers trans-autophosphorylate" +xref: Reactome:R-HSA-9026510 "NTF4-bound NTRK2 dimers trans-autophosphorylate" +xref: Reactome:R-HSA-9026579 "NTRK2 phosphorylates PLCG1" +xref: Reactome:R-HSA-9026890 "NTRK2 phosphorylates SHC1" +xref: Reactome:R-HSA-9027272 "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2" +xref: Reactome:R-HSA-9027273 "JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1" +xref: Reactome:R-HSA-9027425 "LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2" +xref: Reactome:R-HSA-9028728 "NTRK2 phosphorylates FRS2" +xref: Reactome:R-HSA-9029151 "JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1" +xref: Reactome:R-HSA-9029155 "JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1" +xref: Reactome:R-HSA-9032426 "NTRK2 phosphorylates FRS3" +xref: Reactome:R-HSA-9032532 "NTRK2-bound FYN autophosphorylates" +xref: Reactome:R-HSA-9032601 "FYN-mediated phosphorylation of GRIN2B" +xref: Reactome:R-HSA-9032854 "NTRK2 phosphorylates CDK5" +xref: Reactome:R-HSA-9033284 "NTRK2 promotes TIAM1 phosphorylation" +xref: Reactome:R-HSA-9034714 "NTRK3 dimers trans-autophosphorylate" +xref: Reactome:R-HSA-9034814 "NTRK3 phosphorylates PLCG1" +xref: Reactome:R-HSA-9034875 "NTRK3 phosphorylates SHC1" +xref: Reactome:R-HSA-9037040 "SRC,FYN phosphorylate NTRK2" +xref: Reactome:R-HSA-909718 "Formation of p-STAT1 homodimer" +xref: Reactome:R-HSA-909726 "Phosphorylation of STAT1" +xref: Reactome:R-HSA-909729 "Activation of JAK kinases" +xref: Reactome:R-HSA-909730 "Phosphorylation of INFAR1 by TYK2" +xref: Reactome:R-HSA-909732 "Phosphorylation of STAT2" +xref: Reactome:R-HSA-912629 "CBL is tyrosine phosphorylated" +xref: Reactome:R-HSA-9603420 "Activated NTRK3 promotes SRC autophosphorylation" +xref: Reactome:R-HSA-9606159 "BTK autophosphorylates" +xref: Reactome:R-HSA-9606162 "Phosphorylated BTK phosphorylates PLCG2" +xref: Reactome:R-HSA-9606163 "p-SYK and LYN phosphorylate BTK" +xref: Reactome:R-HSA-9612085 "SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs" +xref: Reactome:R-HSA-9612996 "NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates" +xref: Reactome:R-HSA-9613023 "NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates" +xref: Reactome:R-HSA-9625487 "PTK2 autophosphorylates downstream of EGFR" +xref: Reactome:R-HSA-982807 "JAK2 phosphorylation of GHR" +xref: Reactome:R-HSA-983703 "p-6Y-SYK phosphorylates BLNK (SLP65)" +xref: Reactome:R-HSA-983707 "SYK autophosphorylates at the activated BCR" +xref: Reactome:R-HSA-983709 "LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B)" +is_a: GO:0004672 ! protein kinase activity +relationship: part_of GO:0018108 ! peptidyl-tyrosine phosphorylation + +[Term] +id: GO:0004714 +name: transmembrane receptor protein tyrosine kinase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [EC:2.7.10.1, GOC:mah] +synonym: "anaplastic lymphoma kinase activity" NARROW [EC:2.7.10.1] +synonym: "ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity" EXACT [EC:2.7.10.1] +synonym: "ATP:protein-tyrosine O-phosphotransferase activity" BROAD [EC:2.7.10.1] +synonym: "Drosophila Eph kinase activity" NARROW [EC:2.7.10.1] +synonym: "ephrin-B3 receptor tyrosine kinase activity" NARROW [EC:2.7.10.1] +synonym: "insulin receptor protein-tyrosine kinase activity" NARROW [EC:2.7.10.1] +synonym: "neurite outgrowth regulating kinase activity" NARROW [EC:2.7.10.1] +synonym: "neurotrophin TRK receptor activity" RELATED [] +synonym: "neurotrophin TRKA receptor activity" RELATED [] +synonym: "neurotrophin TRKB receptor activity" RELATED [] +synonym: "neurotrophin TRKC receptor activity" RELATED [] +synonym: "novel oncogene with kinase-domain activity" NARROW [EC:2.7.10.1] +synonym: "receptor protein tyrosine kinase activity" EXACT [EC:2.7.10.1] +synonym: "receptor protein-tyrosine kinase activity" EXACT [EC:2.7.10.1] +synonym: "sevenless receptor activity" RELATED [] +xref: EC:2.7.10.1 +xref: MetaCyc:2.7.10.1-RXN +xref: Reactome:R-HSA-166544 "TrkA receptor autophosphorylates" +xref: Reactome:R-HSA-167019 "SHC, complexed with TrkA, is tyrosine-phosphorylated" +xref: Reactome:R-HSA-167683 "TrkA phosphorylates PLCG1" +xref: Reactome:R-HSA-169905 "ARMS is phosphorylated by active TrkA receptor" +xref: Reactome:R-HSA-177933 "SHC1 phosphorylation by phosphorylated EGFR" +xref: Reactome:R-HSA-198295 "TRKA phosphorylates IRS" +xref: Reactome:R-HSA-6784324 "p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA" +xref: Reactome:R-HSA-74711 "Phosphorylation of IRS" +xref: Reactome:R-HSA-74715 "Autophosphorylation of insulin receptor" +xref: Reactome:R-HSA-74742 "Phosphorylation of SHC1" +xref: Reactome:R-HSA-8852552 "MST1R autophosphorylates" +xref: Reactome:R-HSA-8853792 "RET tyrosine phosphorylation" +xref: Reactome:R-HSA-8950269 "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor" +xref: Reactome:R-HSA-8950340 "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation" +xref: Reactome:R-HSA-8950354 "STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction" +xref: Reactome:R-HSA-8950364 "IL23R in IL23:IL23 receptor complex is phosphorylated" +xref: Reactome:R-HSA-8950405 "JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated" +xref: Reactome:R-HSA-8950423 "JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated" +xref: Reactome:R-HSA-8950453 "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4" +xref: Reactome:R-HSA-8950485 "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction" +xref: Reactome:R-HSA-8950537 "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated" +xref: Reactome:R-HSA-8950591 "JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated" +xref: Reactome:R-HSA-8950757 "IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated" +xref: Reactome:R-HSA-8982163 "IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3" +xref: Reactome:R-HSA-8983300 "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1" +xref: Reactome:R-HSA-8983309 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1" +xref: Reactome:R-HSA-8983371 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5" +xref: Reactome:R-HSA-8983424 "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2" +xref: Reactome:R-HSA-8986985 "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5" +xref: Reactome:R-HSA-8986994 "IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2" +xref: Reactome:R-HSA-8986995 "IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA" +xref: Reactome:R-HSA-8987012 "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1" +xref: Reactome:R-HSA-8987040 "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1" +xref: Reactome:R-HSA-8987042 "IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2" +xref: Reactome:R-HSA-8987070 "IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3" +xref: Reactome:R-HSA-8987084 "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1" +xref: Reactome:R-HSA-8987096 "IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3" +xref: Reactome:R-HSA-8987129 "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated" +xref: Reactome:R-HSA-8987141 "IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3" +xref: Reactome:R-HSA-8987150 "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3" +xref: Reactome:R-HSA-8987179 "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3" +xref: Reactome:R-HSA-8987202 "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2" +xref: Reactome:R-HSA-8987255 "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3" +is_a: GO:0004713 ! protein tyrosine kinase activity +is_a: GO:0019199 ! transmembrane receptor protein kinase activity + +[Term] +id: GO:0004715 +name: non-membrane spanning protein tyrosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein." [EC:2.7.10.2] +synonym: "ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [EC:2.7.10.2] +synonym: "ATP:protein-tyrosine O-phosphotransferase activity" BROAD [EC:2.7.10.2] +synonym: "Bruton's tyrosine kinase activity" NARROW [EC:2.7.10.2] +synonym: "cytoplasmic protein tyrosine kinase activity" NARROW [EC:2.7.10.2] +synonym: "focal adhesion kinase activity" NARROW [EC:2.7.10.2] +synonym: "janus kinase 1 activity" NARROW [EC:2.7.10.2] +synonym: "janus kinase 2 activity" NARROW [EC:2.7.10.2] +synonym: "janus kinase 3 activity" NARROW [EC:2.7.10.2] +synonym: "non-specific protein-tyrosine kinase activity" EXACT [EC:2.7.10.2] +synonym: "p60c-src protein tyrosine kinase activity" NARROW [EC:2.7.10.2] +xref: EC:2.7.10.2 +xref: MetaCyc:2.7.10.2-RXN +xref: Reactome:R-HSA-1112602 "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor" +xref: Reactome:R-HSA-1112703 "PTPN11 is phosphorylated" +xref: Reactome:R-HSA-1168423 "JAK2 phosphorylation of IRS-1/2" +xref: Reactome:R-HSA-1168459 "Lyn activates ERK" +xref: Reactome:R-HSA-1168767 "JAK2 phosphorylates STAT1/STAT3" +xref: Reactome:R-HSA-1295519 "IL7R is phosphorylated on Y499" +xref: Reactome:R-HSA-1369115 "SHP2 is phosphorylated" +xref: Reactome:R-HSA-432148 "Fgr may phosphorylate p38 MAPK" +xref: Reactome:R-HSA-437936 "p-Y348-SYK phosphorylates VAV family" +xref: Reactome:R-HSA-453200 "SYK autophosphorylates" +xref: Reactome:R-HSA-6786095 "JAK1 phosphorylates STAT3,STAT6" +xref: Reactome:R-HSA-6786096 "IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated" +xref: Reactome:R-HSA-6788582 "STAT1,STAT3,STAT6 phosphorylation" +xref: Reactome:R-HSA-879910 "JAK2 is phosphorylated, activated" +xref: Reactome:R-HSA-8871373 "BMX phosphorylates RUFY1" +is_a: GO:0004713 ! protein tyrosine kinase activity + +[Term] +id: GO:0004716 +name: obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity +namespace: molecular_function +def: "OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [EC:2.7.10.2] +comment: This term was obsoleted because it was not clearly defined. +synonym: "receptor signaling protein tyrosine kinase activity" EXACT [] +synonym: "receptor signalling protein tyrosine kinase activity" EXACT [] +xref: EC:2.7.10 +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0004717 +name: obsolete focal adhesion kinase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jid] +comment: This term was made obsolete because it represents a gene product, and because the gene was named after its location of action rather than after its molecular function. +synonym: "FAK" EXACT [] +synonym: "focal adhesion kinase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004713 + +[Term] +id: GO:0004719 +name: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester." [EC:2.1.1.77] +synonym: "D-aspartyl/L-isoaspartyl methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "L-aspartyl/L-isoaspartyl protein methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "L-isoaspartyl protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein (D-aspartate) methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein beta-aspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein D-aspartate methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein L-isoaspartate methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein L-isoaspartyl methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein O-methyltransferase (L-isoaspartate)" EXACT [EC:2.1.1.77] +synonym: "protein-beta-aspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein-L-isoaspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "protein-L-isoaspartate(D-aspartate) O-methyltransferase activity" EXACT [EC:2.1.1.77] +synonym: "S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] +xref: EC:2.1.1.77 +xref: MetaCyc:2.1.1.77-RXN +xref: Reactome:R-HSA-5676966 "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp" +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0051998 ! protein carboxyl O-methyltransferase activity + +[Term] +id: GO:0004720 +name: protein-lysine 6-oxidase activity +namespace: molecular_function +alt_id: GO:0018056 +def: "Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide." [EC:1.4.3.13] +synonym: "lysyl oxidase activity" EXACT [EC:1.4.3.13] +synonym: "protein-L-lysine:oxygen 6-oxidoreductase (deaminating)" EXACT [EC:1.4.3.13] +xref: EC:1.4.3.13 +xref: MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN +xref: Reactome:R-HSA-2002466 "Formation of allysine by LOX" +xref: Reactome:R-HSA-2129375 "Elastin cross-linking by lysyl oxidase" +xref: Reactome:R-HSA-2395340 "Formation of hydroxyallysine by LOX" +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004721 +name: phosphoprotein phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity." [EC:3.1.3.16, ISBN:0198547684] +synonym: "phosphoprotein phosphohydrolase activity" EXACT [EC:3.1.3.16] +synonym: "protein phosphatase activity" EXACT [] +synonym: "protein phosphatase-1 activity" NARROW [EC:3.1.3.16] +synonym: "protein phosphatase-2A activity" NARROW [EC:3.1.3.16] +synonym: "protein phosphatase-2B activity" NARROW [EC:3.1.3.16] +synonym: "protein phosphatase-2C activity" NARROW [EC:3.1.3.16] +xref: EC:3.1.3.16 +xref: MetaCyc:3.1.3.16-RXN +xref: Reactome:R-HSA-112383 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein" +xref: Reactome:R-HSA-113503 "PP2A mediated localization of RB1 protein in chromatin" +xref: Reactome:R-HSA-1363274 "Dephosphorylation of p107 (RBL1) by PP2A" +xref: Reactome:R-HSA-1363276 "Dephosphorylation of p130 (RBL2) by PP2A" +xref: Reactome:R-HSA-167072 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein" +xref: Reactome:R-HSA-170153 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases" +xref: Reactome:R-HSA-170158 "Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes" +xref: Reactome:R-HSA-170161 "Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B" +xref: Reactome:R-HSA-174110 "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2" +xref: Reactome:R-HSA-174124 "Dephosphorylation of phospho-Cdh1" +xref: Reactome:R-HSA-178178 "PP1 dephosphorylates TGFBR1" +xref: Reactome:R-HSA-2529015 "Dephosphorylation of CK2-modified condensin I" +xref: Reactome:R-HSA-69199 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A" +is_a: GO:0016791 ! phosphatase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006470 ! protein dephosphorylation + +[Term] +id: GO:0004722 +name: protein serine/threonine phosphatase activity +namespace: molecular_function +alt_id: GO:0000158 +alt_id: GO:0000163 +alt_id: GO:0008598 +alt_id: GO:0008600 +alt_id: GO:0015071 +alt_id: GO:0030357 +alt_id: GO:0030358 +alt_id: GO:0030360 +alt_id: GO:0030361 +def: "Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate." [GOC:bf] +synonym: "3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase" NARROW [EC:3.1.3.16] +synonym: "Aspergillus awamori acid protein phosphatase" NARROW [EC:3.1.3.16] +synonym: "BCKDH phosphatase" NARROW [EC:3.1.3.16] +synonym: "branched-chain alpha-keto acid dehydrogenase phosphatase" NARROW [EC:3.1.3.16] +synonym: "calcineurin" NARROW [] +synonym: "casein phosphatase" NARROW [EC:3.1.3.16] +synonym: "HMG-CoA reductase phosphatase" NARROW [EC:3.1.3.16] +synonym: "phosphatase 2A" NARROW [EC:3.1.3.16] +synonym: "phosphatase 2B" NARROW [EC:3.1.3.16] +synonym: "phosphatase C-II" NARROW [EC:3.1.3.16] +synonym: "phosphatase H-II" NARROW [EC:3.1.3.16] +synonym: "phosphatase I" NARROW [EC:3.1.3.16] +synonym: "phosphatase IB" NARROW [EC:3.1.3.16] +synonym: "phosphatase II" NARROW [EC:3.1.3.16] +synonym: "phosphatase III" NARROW [EC:3.1.3.16] +synonym: "phosphatase IV" NARROW [EC:3.1.3.16] +synonym: "phosphatase SP" NARROW [EC:3.1.3.16] +synonym: "phosphopyruvate dehydrogenase phosphatase" NARROW [EC:3.1.3.16] +synonym: "phosphospectrin phosphatase" NARROW [EC:3.1.3.16] +synonym: "polycation modulated (PCM-) phosphatase" NARROW [EC:3.1.3.16] +synonym: "protein D phosphatase" NARROW [EC:3.1.3.16] +synonym: "protein phosphatase type 1 activity" NARROW [] +synonym: "protein phosphatase type 1, intrinsic catalyst activity" NARROW [] +synonym: "protein phosphatase type 2A activity" NARROW [] +synonym: "protein phosphatase type 2A, intrinsic catalyst activity" NARROW [] +synonym: "protein phosphatase type 2B activity" NARROW [] +synonym: "protein phosphatase type 2B, intrinsic catalyst activity" NARROW [] +synonym: "protein phosphatase type 2C activity" NARROW [] +synonym: "protein phosphatase type 4 activity" NARROW [] +synonym: "protein phosphatase type 4, intrinsic catalyst activity" NARROW [] +synonym: "protein phosphatase X" NARROW [] +synonym: "serine/threonine specific protein phosphatase activity" EXACT [] +xref: Reactome:R-HSA-1295632 "PPA2A dephosphorylates SPRY2" +xref: Reactome:R-HSA-163568 "phosphorylated perilipin + H2O -> perilipin + orthophosphate" +xref: Reactome:R-HSA-1638821 "PP2A-B56 dephosphorylates centromeric cohesin" +xref: Reactome:R-HSA-199425 "PHLPP dephosphorylates S473 in AKT" +xref: Reactome:R-HSA-199959 "ERKs are inactivated by protein phosphatase 2A" +xref: Reactome:R-HSA-201787 "PPP3 complex dephosphorylates DARPP-32 on Thr34" +xref: Reactome:R-HSA-201790 "DARPP-32 is dephosphorylated on Thr75 by PP2A" +xref: Reactome:R-HSA-209055 "PPM1A dephosphorylates nuclear SMAD2/3" +xref: Reactome:R-HSA-2187401 "MTMR4 dephosphorylates SMAD2/3" +xref: Reactome:R-HSA-2995388 "PP2A dephosphorylates BANF1" +xref: Reactome:R-HSA-3002811 "Myosin phosphatase dephosphorylates PLK1" +xref: Reactome:R-HSA-3601585 "PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex" +xref: Reactome:R-HSA-380949 "AMPK is dephosphorylated" +xref: Reactome:R-HSA-4088141 "PP2A-PPP2R2A dephosphorylates FOXM1" +xref: Reactome:R-HSA-429730 "multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate" +xref: Reactome:R-HSA-4419948 "CTDNEP1:CNEP1R1 dephosphorylates LPIN" +xref: Reactome:R-HSA-5672957 "PP2A dephosphorylates KSR1" +xref: Reactome:R-HSA-5672961 "PP2A dephosphorylates inactive RAFs" +xref: Reactome:R-HSA-5675431 "PP2A dephosphorylates RAF1" +xref: Reactome:R-HSA-5675433 "PP5 dephosphorylates RAF1 S338" +xref: Reactome:R-HSA-5679206 "MTMR14, MTMR3 dephosphorylate PI3P" +xref: Reactome:R-HSA-5683405 "PPP5C dephosphorylates TP53BP1" +xref: Reactome:R-HSA-5687758 "PPP4C:PPP4R2 dephosphorylates RPA2" +xref: Reactome:R-HSA-5692754 "CDC14A,B dephosphorylate p-3S,T MAPK6" +xref: Reactome:R-HSA-5693153 "PPM1K dephosphorylates p-BCKDH" +xref: Reactome:R-HSA-5694421 "PP6 dephosphorylates SEC24" +xref: Reactome:R-HSA-6792863 "PP2A-PP2R5C dephosphorylates MDM2" +xref: Reactome:R-HSA-6811504 "AKT1 dephosphorylation by PP2A-B56-beta,gamma" +xref: Reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine" +xref: Reactome:R-HSA-74948 "PP2A dephosphorylates p-RHO to RHO" +xref: Reactome:R-HSA-8948139 "p-S13-FUNDC1 is dephosphorylated by PGAM5" +xref: Reactome:R-HSA-9619430 "PPM1E dephosphorylates CAMK4" +xref: Reactome:R-HSA-9619449 "PPM1F dephosphorylates p-T286-CaMKII" +xref: Reactome:R-HSA-9619467 "PPM1F dephosphorylates CAMK1" +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0004723 +name: calcium-dependent protein serine/threonine phosphatase activity +namespace: molecular_function +alt_id: GO:0008596 +def: "Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions." [EC:3.1.3.16, GOC:mah] +synonym: "calcineurin" NARROW [] +synonym: "calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity" EXACT [] +xref: Reactome:R-HSA-2025882 "Calcineurin dephosphorylates NFATC1,2,3" +is_a: GO:0004722 ! protein serine/threonine phosphatase activity + +[Term] +id: GO:0004724 +name: magnesium-dependent protein serine/threonine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of magnesium." [EC:3.1.3.16] +is_a: GO:0004722 ! protein serine/threonine phosphatase activity + +[Term] +id: GO:0004725 +name: protein tyrosine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48] +synonym: "[phosphotyrosine]protein phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [EC:3.1.3.48] +synonym: "phosphotyrosine histone phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "phosphotyrosine protein phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "phosphotyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "PPT-phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "protein phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "protein-tyrosine-phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "protein-tyrosine-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.48] +synonym: "PTP-phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "PTPase activity" EXACT [EC:3.1.3.48] +synonym: "tyrosine O-phosphate phosphatase activity" EXACT [EC:3.1.3.48] +synonym: "tyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48] +xref: EC:3.1.3.48 +xref: MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN +xref: Reactome:R-HSA-1169188 "SHP1 (PTPN6) dephosphorylates JAK2" +xref: Reactome:R-HSA-1169192 "PTP1B dephosphorylates GHR" +xref: Reactome:R-HSA-1169210 "PTP1B dephosphorylates JAK2" +xref: Reactome:R-HSA-1549564 "PPTN11 dephosphorylates SPRY2" +xref: Reactome:R-HSA-202214 "Dephosphorylation of Lck-pY505 by CD45" +xref: Reactome:R-HSA-203797 "ERKs are inactivated by dual-specific phosphatases (DUSPs)" +xref: Reactome:R-HSA-377643 "Dephosphorylation of inactive SRC by PTPB1" +xref: Reactome:R-HSA-389758 "Dephosphorylation of CD3-zeta by PD-1 bound phosphatases" +xref: Reactome:R-HSA-391868 "Dephosphorylation of NCAM1 bound pFyn" +xref: Reactome:R-HSA-445089 "Dephosphorylation of pL1 (Y1176)" +xref: Reactome:R-HSA-5683967 "EYA1-4 dephosphorylates tyrosine Y142 of H2AFX" +xref: Reactome:R-HSA-6807008 "PTPRJ dephosphorylates MET" +xref: Reactome:R-HSA-6807027 "PTPN1 and PTPN2 dephosphorylate MET" +xref: Reactome:R-HSA-74733 "Insulin receptor de-phosphorylation" +xref: Reactome:R-HSA-74747 "Dephosphorylation of p-Y-IRS1,p-Y-IRS2" +xref: Reactome:R-HSA-74748 "De-phosphorylation of p-Y427-SHC1" +xref: Reactome:R-HSA-877308 "Dephosphorylation of JAKs by PTPs" +xref: Reactome:R-HSA-8849435 "PTPN1 dephosphorylates PTK6" +xref: Reactome:R-HSA-8852200 "Inactivation of LCK by PTPN22" +xref: Reactome:R-HSA-8855381 "PTPN22 dephosphorylates ZAP70" +xref: Reactome:R-HSA-8863804 "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248" +xref: Reactome:R-HSA-8864029 "PTPN12 dephosphorylates EGFR at Y1148 (Y1172)" +xref: Reactome:R-HSA-8864036 "PTPN12 dephosphorylates PDGFRB at Y1021" +xref: Reactome:R-HSA-8864125 "PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248" +xref: Reactome:R-HSA-8867047 "PTPN3 dephosphorylates EPS15" +xref: Reactome:R-HSA-8937767 "PTPN11 dephosphorylates RUNX1" +xref: Reactome:R-HSA-914036 "SHP1 and SHP2 dephosphorylate Y628 of IL3RB" +xref: Reactome:R-HSA-9603719 "Protein tyrosine phosphatases dephosphorylate NTRK3" +xref: Reactome:R-HSA-997309 "Dephosphorylation of STAT1 by SHP2" +xref: Reactome:R-HSA-997311 "Dephosphorylation of TYK2 by PTP1B" +xref: Reactome:R-HSA-997314 "Dephosphorylation of JAK1 by SHP1" +xref: Reactome:R-HSA-997326 "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP" +is_a: GO:0004721 ! phosphoprotein phosphatase activity +relationship: part_of GO:0035335 ! peptidyl-tyrosine dephosphorylation + +[Term] +id: GO:0004726 +name: non-membrane spanning protein tyrosine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate." [EC:3.1.3.48] +xref: Reactome:R-HSA-177923 "Sustained activation of SRC kinase by SHP2" +xref: Reactome:R-HSA-177924 "Dephosphorylation of Gab1 by SHP2" +xref: Reactome:R-HSA-177926 "Dephosphorylation of PAG by SHP2" +xref: Reactome:R-HSA-177935 "SHP2 dephosphorylates Tyr 992 on EGFR" +is_a: GO:0004725 ! protein tyrosine phosphatase activity + +[Term] +id: GO:0004727 +name: prenylated protein tyrosine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate." [EC:3.1.3.48] +is_a: GO:0004725 ! protein tyrosine phosphatase activity + +[Term] +id: GO:0004728 +name: obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48] +comment: This term was obsoleted because it was not clearly defined. +synonym: "receptor signaling protein tyrosine phosphatase activity" EXACT [] +synonym: "receptor signalling protein tyrosine phosphatase activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0004729 +name: oxygen-dependent protoporphyrinogen oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX." [EC:1.3.3.4, RHEA:25576] +synonym: "protoporphyrinogen-IX:oxygen oxidoreductase activity" EXACT [EC:1.3.3.4] +xref: EC:1.3.3.4 +xref: KEGG_REACTION:R03222 +xref: MetaCyc:PROTOPORGENOXI-RXN +xref: Reactome:R-HSA-189423 "PPO oxidises PPGEN9 to PRIN9" +xref: RHEA:25576 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor +is_a: GO:0070818 ! protoporphyrinogen oxidase activity + +[Term] +id: GO:0004730 +name: pseudouridylate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate." [EC:4.2.1.70, RHEA:18337] +comment: Note that this term should not be confused with 'pseudouridine synthase activity ; GO:0009982', which refers to the intramolecular isomerization of uridine to pseudouridine. +synonym: "5-ribosyluracil 5-phosphate synthetase activity" EXACT [EC:4.2.1.70] +synonym: "pseudouridine monophosphate synthase activity" EXACT [] +synonym: "pseudouridine monophosphate synthetase activity" EXACT [EC:4.2.1.70] +synonym: "pseudouridine-5'-phosphate glycosidase activity" EXACT [] +synonym: "pseudouridylate synthetase activity" EXACT [EC:4.2.1.70] +synonym: "pseudouridylic acid synthetase activity" EXACT [EC:4.2.1.70] +synonym: "psiUMP synthetase activity" EXACT [EC:4.2.1.70] +synonym: "uracil hydro-lyase (adding D-ribose 5-phosphate)" EXACT [EC:4.2.1.70] +synonym: "uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)" EXACT [EC:4.2.1.70] +synonym: "uracil hydrolyase activity" RELATED [EC:4.2.1.70] +xref: EC:4.2.1.70 +xref: KEGG_REACTION:R01055 +xref: MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN +xref: RHEA:18337 +is_a: GO:0016836 ! hydro-lyase activity +relationship: part_of GO:0001522 ! pseudouridine synthesis + +[Term] +id: GO:0004731 +name: purine-nucleoside phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate." [EC:2.4.2.1] +synonym: "inosine phosphorylase activity" NARROW [EC:2.4.2.1] +synonym: "inosine-guanosine phosphorylase activity" EXACT [EC:2.4.2.1] +synonym: "PNPase activity" EXACT [EC:2.4.2.1] +synonym: "PUNPI" RELATED [EC:2.4.2.1] +synonym: "PUNPII" RELATED [EC:2.4.2.1] +synonym: "purine deoxynucleoside phosphorylase activity" EXACT [EC:2.4.2.1] +synonym: "purine deoxyribonucleoside phosphorylase activity" EXACT [EC:2.4.2.1] +synonym: "purine nucleoside phosphorylase activity" EXACT [EC:2.4.2.1] +synonym: "purine ribonucleoside phosphorylase activity" EXACT [EC:2.4.2.1] +synonym: "purine-nucleoside:phosphate ribosyltransferase activity" EXACT [EC:2.4.2.1] +xref: EC:2.4.2.1 +xref: MetaCyc:PNP-RXN +xref: Reactome:R-HSA-112033 "hypoxanthine + (deoxy)ribose 1-phosphate <=> (deoxy)inosine + orthophosphate (NP)" +xref: Reactome:R-HSA-112034 "guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate (NP)" +xref: Reactome:R-HSA-74242 "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)" +xref: Reactome:R-HSA-74249 "(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)" +xref: RHEA:19805 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004732 +name: pyridoxal oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide." [EC:1.2.3.8] +synonym: "pyridoxal:oxygen 4-oxidoreductase activity" EXACT [EC:1.2.3.8] +xref: EC:1.2.3.8 +xref: MetaCyc:PYRIDOXAL-OXIDASE-RXN +xref: RHEA:23724 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0004733 +name: pyridoxamine-phosphate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide." [EC:1.4.3.5] +synonym: "PdxH" RELATED [EC:1.4.3.5] +synonym: "PMP oxidase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxal 5'-phosphate synthase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxamine 5'-phosphate oxidase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxamine phosphate oxidase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.5] +synonym: "pyridoxaminephosphate oxidase deaminating" EXACT [EC:1.4.3.5] +synonym: "pyridoxine (pyridoxamine) 5'-phosphate oxidase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxine (pyridoxamine)phosphate oxidase activity" EXACT [EC:1.4.3.5] +synonym: "pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.5] +xref: EC:1.4.3.5 +xref: MetaCyc:PMPOXI-RXN +xref: Reactome:R-HSA-965019 "2xPNPO:2xFMN oxidizes PDXP to PXLP" +xref: Reactome:R-HSA-965079 "2xPNPO:2xFMN oxidizes PXAP to PXLP" +xref: RHEA:15817 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor +relationship: part_of GO:0042823 ! pyridoxal phosphate biosynthetic process + +[Term] +id: GO:0004734 +name: pyrimidodiazepine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione." [EC:1.5.4.1] +synonym: "PDA synthase activity" EXACT [EC:1.5.4.1] +synonym: "pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)" EXACT [EC:1.5.4.1] +xref: EC:1.5.4.1 +xref: MetaCyc:1.5.4.1-RXN +is_a: GO:0016648 ! oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor + +[Term] +id: GO:0004735 +name: pyrroline-5-carboxylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+." [EC:1.5.1.2] +synonym: "1-pyrroline-5-carboxylate reductase activity" EXACT [EC:1.5.1.2] +synonym: "L-proline oxidase activity" EXACT [EC:1.5.1.2] +synonym: "L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [EC:1.5.1.2] +synonym: "L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [EC:1.5.1.2] +synonym: "NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [EC:1.5.1.2] +synonym: "P5CR activity" EXACT [EC:1.5.1.2] +xref: EC:1.5.1.2 +xref: MetaCyc:PYRROLINECARBREDUCT-RXN +xref: Reactome:R-HSA-6783939 "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro" +xref: Reactome:R-HSA-6783955 "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro" +xref: Reactome:R-HSA-70664 "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro" +xref: RHEA:14109 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004736 +name: pyruvate carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate." [EC:6.4.1.1, RHEA:20844] +synonym: "pyruvate:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.1] +synonym: "pyruvic carboxylase activity" EXACT [EC:6.4.1.1] +xref: EC:6.4.1.1 +xref: KEGG_REACTION:R00344 +xref: MetaCyc:PYRUVATE-CARBOXYLASE-RXN +xref: Reactome:R-HSA-70501 "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate" +xref: RHEA:20844 +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0004737 +name: pyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2." [EC:4.1.1.1] +synonym: "2-oxo-acid carboxy-lyase (aldehyde-forming)" EXACT [EC:4.1.1.1] +synonym: "2-oxo-acid carboxy-lyase activity" EXACT [EC:4.1.1.1] +synonym: "alpha-carboxylase activity" EXACT [EC:4.1.1.1] +synonym: "alpha-ketoacid carboxylase activity" EXACT [EC:4.1.1.1] +synonym: "pyruvic decarboxylase activity" EXACT [EC:4.1.1.1] +xref: EC:4.1.1.1 +xref: MetaCyc:PYRUVATE-DECARBOXYLASE-RXN +xref: RHEA:11628 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004738 +name: pyruvate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the oxidative decarboxylation of pyruvate." [ISBN:0716720094] +synonym: "pyruvic acid dehydrogenase activity" EXACT [EC:1.2.4.1] +synonym: "pyruvic dehydrogenase activity" EXACT [EC:1.2.4.1] +xref: MetaCyc:PYRUVOXID-RXN +xref: MetaCyc:RXN0-1134 +xref: Reactome:R-HSA-71397 "lipo-PDH decarboxylates PYR to Ac-CoA" +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0004739 +name: pyruvate dehydrogenase (acetyl-transferring) activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2." [EC:1.2.4.1] +synonym: "MtPDC (mitochondrial pyruvate dehydogenase complex) activity" NARROW [EC:1.2.4.1] +synonym: "PDH" RELATED [EC:1.2.4.1] +synonym: "pyruvate dehydrogenase (lipoamide) activity" EXACT [] +synonym: "pyruvate dehydrogenase complex activity" RELATED [EC:1.2.4.1] +synonym: "pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)" EXACT [EC:1.2.4.1] +synonym: "pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity" EXACT [EC:1.2.4.1] +xref: EC:1.2.4.1 +is_a: GO:0004738 ! pyruvate dehydrogenase activity +is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor + +[Term] +id: GO:0004740 +name: pyruvate dehydrogenase (acetyl-transferring) kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate." [EC:2.7.11.2] +synonym: "[pyruvate dehydrogenase (lipoamide)] kinase activity" EXACT [] +synonym: "ATP:pyruvate dehydrogenase (acetyl-transferring) phosphotransferase activity" EXACT [EC:2.7.11.2] +synonym: "PDH kinase activity" EXACT [EC:2.7.11.2] +synonym: "PDHK" RELATED [EC:2.7.11.2] +synonym: "PDK" RELATED [EC:2.7.11.2] +synonym: "PDK1" RELATED [EC:2.7.11.2] +synonym: "PDK2" RELATED [EC:2.7.11.2] +synonym: "PDK3" RELATED [EC:2.7.11.2] +synonym: "PDK4" RELATED [EC:2.7.11.2] +synonym: "pyruvate dehydrogenase (lipoamide) kinase activity" EXACT [] +synonym: "pyruvate dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.2] +synonym: "pyruvate dehydrogenase kinase activator protein activity" NARROW [EC:2.7.11.2] +synonym: "pyruvate dehydrogenase kinase activity" EXACT [EC:2.7.11.2] +synonym: "STK1" RELATED [EC:2.7.11.2] +xref: EC:2.7.11.2 +xref: MetaCyc:2.7.11.2-RXN +xref: Reactome:R-HSA-203946 "PDK isoforms phosphorylate lipo-PDH" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0004741 +name: [pyruvate dehydrogenase (lipoamide)] phosphatase activity +namespace: molecular_function +alt_id: GO:0019906 +def: "Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate." [EC:3.1.3.43] +synonym: "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity" EXACT [] +synonym: "phosphopyruvate dehydrogenase phosphatase activity" EXACT [EC:3.1.3.43] +synonym: "pyruvate dehydrogenase (lipoamide) phosphatase activity" EXACT [] +synonym: "pyruvate dehydrogenase (lipoamide)-phosphatase activity" EXACT [EC:3.1.3.43] +synonym: "pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.43] +synonym: "pyruvate dehydrogenase phosphatase activity" EXACT [EC:3.1.3.43] +xref: EC:3.1.3.43 +xref: MetaCyc:3.1.3.43-RXN +xref: Reactome:R-HSA-204169 "PDP dephosphorylates p-lipo-PDH" +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0004742 +name: dihydrolipoyllysine-residue acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide." [EC:2.3.1.12] +synonym: "acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "acetyl-CoA:dihydrolipoamide S-acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "dihydrolipoamide S-acetyltransferase activity" EXACT [] +synonym: "dihydrolipoate acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "dihydrolipoic transacetylase activity" EXACT [EC:2.3.1.12] +synonym: "dihydrolipoyl acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "lipoate acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "lipoate transacetylase activity" EXACT [EC:2.3.1.12] +synonym: "lipoic acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "lipoic acid acetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "lipoic transacetylase activity" EXACT [EC:2.3.1.12] +synonym: "lipoylacetyltransferase activity" EXACT [EC:2.3.1.12] +synonym: "thioltransacetylase A activity" NARROW [EC:2.3.1.12] +synonym: "transacetylase X activity" NARROW [EC:2.3.1.12] +xref: EC:2.3.1.12 +is_a: GO:0016418 ! S-acetyltransferase activity +is_a: GO:0030523 ! dihydrolipoamide S-acyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004743 +name: pyruvate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate." [EC:2.7.1.40, RHEA:18159] +synonym: "ATP:pyruvate 2-O-phosphotransferase activity" EXACT [EC:2.7.1.40] +synonym: "phosphoenol transphosphorylase activity" EXACT [EC:2.7.1.40] +synonym: "phosphoenolpyruvate kinase activity" EXACT [EC:2.7.1.40] +xref: EC:2.7.1.40 +xref: MetaCyc:PEPDEPHOS-RXN +xref: Reactome:R-HSA-71670 "phosphoenolpyruvate + ADP => pyruvate + ATP, Homo sapiens" +xref: RHEA:18159 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +relationship: part_of GO:0006096 ! glycolytic process + +[Term] +id: GO:0004744 +name: retinal isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinal = 11-cis-retinal." [RHEA:24124] +synonym: "all-trans-retinal 11-cis-trans-isomerase activity" EXACT [EC:5.2.1.3] +synonym: "retinene isomerase activity" RELATED [EC:5.2.1.3] +synonym: "retinoid isomerase activity" BROAD [EC:5.2.1.3] +xref: KEGG_REACTION:R02126 +xref: MetaCyc:RETINAL-ISOMERASE-RXN +xref: RHEA:24124 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0004745 +name: retinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+." [EC:1.1.1.105] +synonym: "all-trans retinol dehydrogenase activity" BROAD [EC:1.1.1.105] +synonym: "MDR" RELATED [EC:1.1.1.105] +synonym: "microsomal retinol dehydrogenase activity" BROAD [EC:1.1.1.105] +synonym: "retinal reductase activity" BROAD [GOC:ecd, PMID:12036956] +synonym: "retinene reductase activity" BROAD [EC:1.1.1.105] +synonym: "retinol (vitamin A1) dehydrogenase activity" BROAD [EC:1.1.1.105] +synonym: "retinol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.105] +xref: EC:1.1.1.105 +xref: MetaCyc:RETINOL-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-2454081 "RDH5 oxidises 11cROL to 11cRAL" +xref: Reactome:R-HSA-2466832 "Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA" +xref: Reactome:R-HSA-5362518 "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL" +xref: Reactome:R-HSA-5362564 "ADH1A,1C,4 oxidise atROL to atRAL in vitro" +xref: Reactome:R-HSA-5362721 "RDH5,RDH11 oxidise 11cROL to 11cRAL" +xref: RHEA:21284 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004746 +name: riboflavin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin." [EC:2.5.1.9, RHEA:20772] +synonym: "6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity" EXACT [EC:2.5.1.9] +synonym: "heavy riboflavin synthase" NARROW [EC:2.5.1.9] +synonym: "light riboflavin synthase" NARROW [EC:2.5.1.9] +synonym: "lumazine synthase activity" BROAD [BRENDA:2.5.1.9] +synonym: "riboflavin synthetase activity" EXACT [EC:2.5.1.9] +synonym: "riboflavine synthase activity" EXACT [EC:2.5.1.9] +synonym: "riboflavine synthetase activity" EXACT [EC:2.5.1.9] +synonym: "vitamin B2 synthase activity" EXACT [] +xref: EC:2.5.1.9 +xref: KEGG_REACTION:R00066 +xref: MetaCyc:RIBOFLAVIN-SYN-RXN +xref: RHEA:20772 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004747 +name: ribokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate." [EC:2.7.1.15] +synonym: "ATP:D-ribose 5-phosphotransferase activity" EXACT [EC:2.7.1.15] +synonym: "D-ribokinase activity" EXACT [EC:2.7.1.15] +synonym: "deoxyribokinase activity" EXACT [EC:2.7.1.15] +synonym: "ribokinase (phosphorylating)" EXACT [EC:2.7.1.15] +xref: EC:2.7.1.15 +xref: MetaCyc:RIBOKIN-RXN +xref: Reactome:R-HSA-8955844 "RBKS phosphorylates ribose to R5P" +xref: RHEA:13697 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0004748 +name: ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor +namespace: molecular_function +alt_id: GO:0016959 +alt_id: GO:0016960 +alt_id: GO:0016961 +def: "Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.17.4.1] +comment: When thioredoxin is substituted for glutaredoxin in the reaction, annotate instead to 'ribonucleoside-diphosphate reductase, glutaredoxin disulfide as acceptor ; GO:0036175'. +synonym: "2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity" EXACT [EC:1.17.4.1] +synonym: "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity" EXACT [EC:1.17.4.1] +xref: EC:1.17.4.1 +xref: MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN +xref: Reactome:R-HSA-111751 "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)" +xref: Reactome:R-HSA-111804 "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)" +xref: RHEA:23252 +is_a: GO:0061731 ! ribonucleoside-diphosphate reductase activity + +[Term] +id: GO:0004749 +name: ribose phosphate diphosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+)." [EC:2.7.6.1, RHEA:15609] +synonym: "5-phosphoribose pyrophosphorylase activity" EXACT [EC:2.7.6.1] +synonym: "5-phosphoribosyl-1-pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "ATP:D-ribose-5-phosphate diphosphotransferase activity" EXACT [EC:2.7.6.1] +synonym: "phosphoribosyl diphosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "phosphoribosyl pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "phosphoribosyl-diphosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "phosphoribosylpyrophosphate synthase activity" EXACT [EC:2.7.6.1] +synonym: "phosphoribosylpyrophosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "PP-ribose P synthetase activity" EXACT [EC:2.7.6.1] +synonym: "PPRibP synthetase activity" EXACT [EC:2.7.6.1] +synonym: "PRPP synthetase activity" EXACT [EC:2.7.6.1] +synonym: "pyrophosphoribosylphosphate synthetase activity" EXACT [EC:2.7.6.1] +synonym: "ribophosphate pyrophosphokinase activity" EXACT [EC:2.7.6.1] +synonym: "ribose-5-phosphate pyrophosphokinase activity" EXACT [EC:2.7.6.1] +synonym: "ribose-phosphate diphosphokinase activity" EXACT [EC:2.7.6.1] +synonym: "ribose-phosphate pyrophosphokinase activity" EXACT [] +xref: EC:2.7.6.1 +xref: KEGG_REACTION:R01049 +xref: MetaCyc:PRPPSYN-RXN +xref: MetaCyc:PWY0-662 +xref: Reactome:R-HSA-111215 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate" +xref: Reactome:R-HSA-73580 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate" +xref: RHEA:15609 +is_a: GO:0016778 ! diphosphotransferase activity + +[Term] +id: GO:0004750 +name: ribulose-phosphate 3-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate." [EC:5.1.3.1, RHEA:13677] +synonym: "D-ribulose 5-phosphate epimerase activity" EXACT [EC:5.1.3.1] +synonym: "D-ribulose phosphate-3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "D-ribulose-5-P 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "D-ribulose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "D-ribulose-5-phosphate epimerase activity" EXACT [EC:5.1.3.1] +synonym: "D-xylulose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "erythrose-4-phosphate epimerase activity" EXACT [EC:5.1.3.1] +synonym: "erythrose-4-phosphate isomerase activity" EXACT [EC:5.1.3.1] +synonym: "pentose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "phosphoketopentose 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "phosphoketopentose epimerase activity" EXACT [EC:5.1.3.1] +synonym: "phosphoribulose epimerase activity" EXACT [EC:5.1.3.1] +synonym: "ribulose 5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] +synonym: "xylulose phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] +xref: EC:5.1.3.1 +xref: KEGG_REACTION:R01529 +xref: MetaCyc:RIBULP3EPIM-RXN +xref: Reactome:R-HSA-199803 "xylulose 5-phosphate <=> D-ribulose 5-phosphate" +xref: Reactome:R-HSA-71303 "RPE dimers isomerise RU5P to XY5P" +xref: RHEA:13677 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0004751 +name: ribose-5-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate." [EC:5.3.1.6, RHEA:14657] +synonym: "5-phosphoribose isomerase activity" EXACT [EC:5.3.1.6] +synonym: "D-ribose 5-phosphate isomerase activity" EXACT [EC:5.3.1.6] +synonym: "D-ribose-5-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.6] +synonym: "D-ribose-5-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.6] +synonym: "phosphopentoseisomerase activity" EXACT [EC:5.3.1.6] +synonym: "phosphopentosisomerase activity" EXACT [EC:5.3.1.6] +synonym: "phosphoriboisomerase activity" EXACT [EC:5.3.1.6] +synonym: "ribose 5-phosphate epimerase activity" EXACT [EC:5.3.1.6] +synonym: "ribose phosphate isomerase activity" EXACT [EC:5.3.1.6] +xref: EC:5.3.1.6 +xref: KEGG_REACTION:R01056 +xref: MetaCyc:RIB5PISOM-RXN +xref: Reactome:R-HSA-177784 "ribose 5-phosphate <=> D-ribulose 5-phosphate" +xref: Reactome:R-HSA-5660013 "Defective RPIA does not isomerize RU5P to R5P" +xref: Reactome:R-HSA-5660015 "Defective RPIA does not isomerize R5P to RU5P" +xref: Reactome:R-HSA-71306 "D-ribulose 5-phosphate <=> ribose 5-phosphate" +xref: RHEA:14657 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004753 +name: saccharopine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor." [GOC:mah] +synonym: "lysine-2-oxoglutarate reductase activity" EXACT [EC:1.5.1.-] +synonym: "lysine-ketoglutarate reductase activity" EXACT [EC:1.5.1.-] +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004754 +name: saccharopine dehydrogenase (NAD+, L-lysine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH." [EC:1.5.1.7, RHEA:12440] +synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] +synonym: "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)" EXACT [EC:1.5.1.7] +synonym: "epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)" EXACT [EC:1.5.1.7] +synonym: "N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] +synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] +xref: EC:1.5.1.7 +xref: KEGG_REACTION:R00715 +xref: MetaCyc:1.5.1.7-RXN +xref: RHEA:12440 +is_a: GO:0004753 ! saccharopine dehydrogenase activity + +[Term] +id: GO:0004755 +name: saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH." [EC:1.5.1.10, RHEA:10020] +synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.10] +synonym: "aminoadipate semialdehyde-glutamate reductase activity" EXACT [EC:1.5.1.10] +synonym: "aminoadipic semialdehyde-glutamate reductase activity" EXACT [EC:1.5.1.10] +synonym: "aminoadipic semialdehyde-glutamic reductase activity" EXACT [EC:1.5.1.10] +synonym: "epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)" EXACT [EC:1.5.1.10] +synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.10] +synonym: "saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity" EXACT [EC:1.5.1.10] +synonym: "saccharopine reductase activity" EXACT [EC:1.5.1.10] +xref: EC:1.5.1.10 +xref: KEGG_REACTION:R02315 +xref: MetaCyc:RXN3O-127 +xref: RHEA:10020 +is_a: GO:0004753 ! saccharopine dehydrogenase activity + +[Term] +id: GO:0004756 +name: selenide, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate." [EC:2.7.9.3, RHEA:18737] +synonym: "ATP:selenide, water phosphotransferase activity" EXACT [EC:2.7.9.3] +synonym: "selenide,water dikinase activity" EXACT [EC:2.7.9.3] +synonym: "selenium donor protein activity" EXACT [EC:2.7.9.3] +synonym: "selenophosphate synthase activity" EXACT [] +synonym: "selenophosphate synthetase activity" EXACT [EC:2.7.9.3] +xref: EC:2.7.9.3 +xref: KEGG_REACTION:R03595 +xref: MetaCyc:2.7.9.3-RXN +xref: Reactome:R-HSA-8959510 "SEPHS2 phosphorylates H2Se to form SELP" +xref: RHEA:18737 +xref: UM-BBD_reactionID:r0833 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0004757 +name: sepiapterin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+." [EC:1.1.1.153] +synonym: "7,8-dihydrobiopterin:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.153] +xref: EC:1.1.1.153 +xref: MetaCyc:SEPIAPTERIN-REDUCTASE-RXN +xref: Reactome:R-HSA-1475414 "PTHP is reduced to BH4 by sepiapterin reductase (SPR)" +xref: Reactome:R-HSA-1497869 "Salvage - Sepiapterin is reduced to BH2" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004758 +name: serine C-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA." [EC:2.3.1.50, RHEA:14761] +synonym: "3-oxosphinganine synthetase activity" EXACT [EC:2.3.1.50] +synonym: "acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [EC:2.3.1.50] +synonym: "palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [EC:2.3.1.50] +synonym: "serine palmitoyltransferase" BROAD [] +synonym: "SPT" RELATED [EC:2.3.1.50] +xref: EC:2.3.1.50 +xref: KEGG_REACTION:R01281 +xref: MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN +xref: Reactome:R-HSA-428127 "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2" +xref: RHEA:14761 +is_a: GO:0016454 ! C-palmitoyltransferase activity + +[Term] +id: GO:0004760 +name: serine-pyruvate transaminase activity +namespace: molecular_function +alt_id: GO:0004761 +alt_id: GO:0004762 +alt_id: GO:0004763 +def: "Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine." [EC:2.6.1.51, RHEA:22852] +synonym: "hydroxypyruvate:L-alanine transaminase activity" EXACT [EC:2.6.1.51] +synonym: "L-serine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.51] +synonym: "serine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.51] +synonym: "serine-pyruvate aminotransferase activity" EXACT [] +synonym: "serine-pyruvate aminotransferase, type 1" NARROW [] +synonym: "serine-pyruvate aminotransferase, type 2A" NARROW [] +synonym: "serine-pyruvate aminotransferase, type 2B" NARROW [] +synonym: "SPT" RELATED [EC:2.6.1.51] +xref: EC:2.6.1.51 +xref: KEGG_REACTION:R00585 +xref: MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN +xref: RHEA:22852 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0004764 +name: shikimate 3-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+." [EC:1.1.1.25] +synonym: "5-dehydroshikimate reductase activity" EXACT [EC:1.1.1.25] +synonym: "5-dehydroshikimic reductase activity" EXACT [EC:1.1.1.25] +synonym: "dehydroshikimic reductase activity" BROAD [EC:1.1.1.25] +synonym: "DHS reductase activity" BROAD [EC:1.1.1.25] +synonym: "shikimate oxidoreductase activity" BROAD [EC:1.1.1.25] +synonym: "shikimate:NADP(+) 5-oxidoreductase activity" EXACT [EC:1.1.1.25] +synonym: "shikimate:NADP(+) oxidoreductase activity" BROAD [EC:1.1.1.25] +xref: EC:1.1.1.25 +xref: EC:1.1.1.282 +xref: KEGG_REACTION:R06847 +xref: MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN +xref: RHEA:17737 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0004765 +name: shikimate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+)." [EC:2.7.1.71, RHEA:13121] +synonym: "ATP:shikimate 3-phosphotransferase activity" EXACT [EC:2.7.1.71] +synonym: "shikimate kinase (phosphorylating)" EXACT [EC:2.7.1.71] +synonym: "shikimate kinase II" RELATED [EC:2.7.1.71] +xref: EC:2.7.1.71 +xref: KEGG_REACTION:R02412 +xref: MetaCyc:SHIKIMATE-KINASE-RXN +xref: RHEA:13121 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0004766 +name: spermidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine." [EC:2.5.1.16] +synonym: "aminopropyltransferase activity" EXACT [EC:2.5.1.16] +synonym: "putrescine aminopropyltransferase activity" EXACT [EC:2.5.1.16] +synonym: "S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.16] +synonym: "SpeE" RELATED [EC:2.5.1.16] +synonym: "spermidine synthetase activity" EXACT [EC:2.5.1.16] +xref: EC:2.5.1.16 +xref: MetaCyc:SPERMIDINESYN-RXN +xref: Reactome:R-HSA-351215 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine" +xref: RHEA:12721 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004767 +name: sphingomyelin phosphodiesterase activity +namespace: molecular_function +alt_id: GO:0030230 +alt_id: GO:0030231 +def: "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+)." [EC:3.1.4.12, RHEA:19253] +subset: goslim_chembl +synonym: "sphingomyelin cholinephosphohydrolase activity" EXACT [EC:3.1.4.12] +synonym: "sphingomyelinase activity" EXACT [] +xref: EC:3.1.4.12 +xref: KEGG_REACTION:R02541 +xref: MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN +xref: Reactome:R-HSA-1605797 "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)" +xref: Reactome:R-HSA-1606273 "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)" +xref: Reactome:R-HSA-1606288 "Sphingomyelin phosphodiesterase 4 (SMPD4) hydrolyses sphingomyelin to ceramide (ER membrane)" +xref: Reactome:R-HSA-1640164 "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin" +xref: Reactome:R-HSA-193706 "Production of ceramide which can activate JNK and other targets" +xref: RHEA:19253 +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0004768 +name: stearoyl-CoA 9-desaturase activity +namespace: molecular_function +alt_id: GO:0016214 +alt_id: GO:0043735 +def: "Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O." [EC:1.14.19.1] +comment: Note that this function was formerly EC:1.14.99.5. +synonym: "acyl-CoA desaturase activity" BROAD [EC:1.14.19.1] +synonym: "delta(9)-desaturase activity" BROAD [EC:1.14.19.1] +synonym: "delta-9 acyl-phospholipid desaturase activity" RELATED [] +synonym: "delta9-desaturase activity" BROAD [EC:1.14.19.1] +synonym: "fatty acid desaturase activity" BROAD [EC:1.14.19.1] +synonym: "stearoyl-CoA desaturase activity" BROAD [] +synonym: "stearoyl-CoA, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.1] +synonym: "stearoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating)" EXACT [EC:1.14.19.1] +xref: EC:1.14.19.1 +xref: MetaCyc:1.14.19.1-RXN +xref: Reactome:R-HSA-5690565 "SCD desaturates ST-CoA to OLE-CoA" +xref: Reactome:R-HSA-8847579 "SCD5 desaturates ST-CoA to OLE-CoA" +is_a: GO:0016215 ! acyl-CoA desaturase activity + +[Term] +id: GO:0004769 +name: steroid delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid." [EC:5.3.3.1] +synonym: "3-oxosteroid delta5-delta4-isomerase activity" EXACT [EC:5.3.3.1] +synonym: "3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta(5)-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta(5)-3-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta(5)-3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta(5)-steroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5(or delta4)-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5-3-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5-3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "delta5-steroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "hydroxysteroid isomerase activity" EXACT [EC:5.3.3.1] +synonym: "steroid D-isomerase activity" EXACT [] +synonym: "steroid isomerase activity" EXACT [EC:5.3.3.1] +xref: EC:5.3.3.1 +xref: MetaCyc:STEROID-DELTA-ISOMERASE-RXN +xref: Reactome:R-HSA-193052 "Pregn-5-ene-3,20-dione isomerizes to progesterone" +xref: Reactome:R-HSA-193073 "DHA isomerizes to 4-Androstene3,17-dione" +xref: Reactome:R-HSA-193961 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone" +xref: Reactome:R-HSA-195690 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol" +xref: Reactome:R-HSA-6807052 "EBP isomerizes ZYMSTNL to LTHSOL" +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0004771 +name: sterol esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid." [EC:3.1.1.13] +subset: goslim_chembl +synonym: "acylcholesterol lipase activity" EXACT [EC:3.1.1.13] +synonym: "cholesterase activity" EXACT [EC:3.1.1.13] +synonym: "cholesterol ester hydrolase activity" EXACT [EC:3.1.1.13] +synonym: "cholesterol ester synthase activity" NARROW [EC:3.1.1.13] +synonym: "cholesterol esterase activity" NARROW [EC:3.1.1.13] +synonym: "cholesteryl ester hydrolase activity" EXACT [EC:3.1.1.13] +synonym: "cholesteryl ester synthase activity" EXACT [EC:3.1.1.13] +synonym: "cholesteryl esterase activity" EXACT [EC:3.1.1.13] +synonym: "sterol ester hydrolase activity" EXACT [EC:3.1.1.13] +synonym: "steryl-ester acylhydrolase activity" EXACT [EC:3.1.1.13] +synonym: "triterpenol esterase activity" EXACT [EC:3.1.1.13] +xref: EC:3.1.1.13 +xref: MetaCyc:STEROL-ESTERASE-RXN +xref: Reactome:R-HSA-192417 "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)" +xref: Reactome:R-HSA-6813720 "NCEH1 hydrolyzes cholesterol esters" +xref: Reactome:R-HSA-8865667 "LIPA hydrolyses sterol esters to sterols and fatty acids" +is_a: GO:0016298 ! lipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004772 +name: sterol O-acyltransferase activity +namespace: molecular_function +alt_id: GO:0017066 +def: "Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester." [EC:2.3.1.26, GOC:mah] +synonym: "sterol-ester synthase activity" EXACT [EC:2.3.1.26] +synonym: "sterol-ester synthetase activity" EXACT [EC:2.3.1.26] +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0004773 +name: steryl-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate." [EC:3.1.6.2] +synonym: "3-beta-hydroxysteroid sulfate sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "arylsulfatase C activity" EXACT [EC:3.1.6.2] +synonym: "dehydroepiandrosterone sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "dehydroepiandrosterone sulfate sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "phenolic steroid sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "pregnenolone sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "steroid 3-sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "steroid sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "steroid sulfate sulfohydrolase activity" EXACT [EC:3.1.6.2] +synonym: "sterol sulfatase activity" EXACT [EC:3.1.6.2] +synonym: "steryl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.2] +synonym: "steryl-sulphatase activity" EXACT [] +xref: EC:3.1.6.2 +xref: MetaCyc:STERYL-SULFATASE-RXN +xref: Reactome:R-HSA-1606839 "Steryl sulfatase hydrolyses sulfate from steroid sulfates" +xref: RHEA:19873 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0004774 +name: succinate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA." [GOC:ai] +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0004775 +name: succinate-CoA ligase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate." [EC:6.2.1.5] +synonym: "A-SCS" RELATED [EC:6.2.1.5] +synonym: "A-STK (adenin nucleotide-linked succinate thiokinase)" RELATED [EC:6.2.1.5] +synonym: "succinate thiokinase activity" EXACT [EC:6.2.1.5] +synonym: "succinate:CoA ligase (ADP-forming) activity" EXACT [EC:6.2.1.5] +synonym: "succinic thiokinase" BROAD [EC:6.2.1.5] +synonym: "succinyl coenzyme A synthetase" BROAD [EC:6.2.1.5] +synonym: "succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity" EXACT [EC:6.2.1.5] +synonym: "succinyl-CoA synthetase (ADP-forming) activity" EXACT [EC:6.2.1.5] +synonym: "succinyl-CoA synthetase activity" EXACT [EC:6.2.1.5] +xref: EC:6.2.1.5 +xref: KEGG_REACTION:R00405 +xref: MetaCyc:SUCCCOASYN-RXN +xref: Reactome:R-HSA-70997 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA" +xref: RHEA:17661 +is_a: GO:0004774 ! succinate-CoA ligase activity + +[Term] +id: GO:0004776 +name: succinate-CoA ligase (GDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate." [EC:6.2.1.4] +synonym: "G-STK" RELATED [EC:6.2.1.4] +synonym: "P-enzyme" RELATED [EC:6.2.1.4] +synonym: "SCS" RELATED [EC:6.2.1.4] +synonym: "succinate-phosphorylating enzyme" RELATED [EC:6.2.1.4] +synonym: "succinate:CoA ligase (GDP-forming) activity" EXACT [EC:6.2.1.4] +synonym: "succinic thiokinase" BROAD [EC:6.2.1.4] +synonym: "succinyl CoA synthetase activity" EXACT [EC:6.2.1.4] +synonym: "succinyl coenzyme A synthetase" BROAD [EC:6.2.1.4] +synonym: "succinyl coenzyme A synthetase (GDP-forming) activity" EXACT [EC:6.2.1.4] +synonym: "succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity" EXACT [EC:6.2.1.4] +synonym: "succinyl-CoA synthetase (GDP-forming) activity" EXACT [EC:6.2.1.4] +xref: EC:6.2.1.4 +xref: KEGG_REACTION:R00432 +xref: MetaCyc:SUCCINATE--COA-LIGASE-GDP-FORMING-RXN +xref: Reactome:R-HSA-71775 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA" +xref: RHEA:22120 +is_a: GO:0004774 ! succinate-CoA ligase activity + +[Term] +id: GO:0004777 +name: succinate-semialdehyde dehydrogenase (NAD+) activity +namespace: molecular_function +alt_id: GO:0008952 +def: "Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+." [EC:1.2.1.24] +synonym: "succinate semialdehyde dehydrogenase activity" BROAD [EC:1.2.1.24] +synonym: "succinate semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.24] +synonym: "succinate-semialdehyde dehydrogenase activity" BROAD [GOC:bf] +synonym: "succinate-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.24] +synonym: "succinic semialdehyde dehydrogenase activity" BROAD [EC:1.2.1.24] +synonym: "succinyl semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.24] +xref: EC:1.2.1.24 +xref: MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-888548 "Conversion of succinate semialdehyde to succinate" +xref: RHEA:13217 +is_a: GO:0009013 ! succinate-semialdehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0004778 +name: succinyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate." [EC:3.1.2.3, RHEA:11516] +synonym: "succinyl coenzyme A deacylase activity" EXACT [EC:3.1.2.3] +synonym: "succinyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.3] +synonym: "succinyl-CoA acylase activity" EXACT [EC:3.1.2.3] +xref: EC:3.1.2.3 +xref: KEGG_REACTION:R00407 +xref: MetaCyc:SUCCINYL-COA-HYDROLASE-RXN +xref: RHEA:11516 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0004779 +name: sulfate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate." [GOC:mah, MetaCyc:SULFATE-ADENYLYLTRANS-RXN, MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN] +synonym: "sulphate adenylyltransferase activity" EXACT [] +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0004780 +name: sulfate adenylyltransferase (ADP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate." [EC:2.7.7.5, RHEA:16529] +synonym: "adenosine diphosphate sulfurylase activity" EXACT [EC:2.7.7.5] +synonym: "ADP-sulfurylase activity" EXACT [EC:2.7.7.5] +synonym: "ADP:sulfate adenylyltransferase activity" EXACT [] +synonym: "sulfate (adenosine diphosphate) adenylyltransferase activity" EXACT [EC:2.7.7.5] +synonym: "sulphate adenylyltransferase (ADP) activity" EXACT [] +xref: EC:2.7.7.5 +xref: KEGG_REACTION:R00530 +xref: MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN +xref: RHEA:16529 +is_a: GO:0004779 ! sulfate adenylyltransferase activity + +[Term] +id: GO:0004781 +name: sulfate adenylyltransferase (ATP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate." [EC:2.7.7.4] +synonym: "adenosine-5'-triphosphate sulfurylase activity" EXACT [EC:2.7.7.4] +synonym: "adenosinetriphosphate sulfurylase activity" EXACT [EC:2.7.7.4] +synonym: "adenylylsulfate pyrophosphorylase activity" EXACT [EC:2.7.7.4] +synonym: "ATP sulfurylase activity" EXACT [EC:2.7.7.4] +synonym: "ATP-sulfurylase activity" EXACT [EC:2.7.7.4] +synonym: "ATP:sulfate adenylyltransferase activity" EXACT [] +synonym: "sulfate adenylate transferase activity" EXACT [EC:2.7.7.4] +synonym: "sulfurylase activity" RELATED [EC:2.7.7.4] +synonym: "sulphate adenylyltransferase (ATP) activity" EXACT [] +xref: EC:2.7.7.4 +xref: MetaCyc:SULFATE-ADENYLYLTRANS-RXN +xref: Reactome:R-HSA-174392 "PAPSS1,2 transfer SO4(2-) group to ATP to form APS" +xref: Reactome:R-HSA-3560794 "Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS" +xref: RHEA:18133 +is_a: GO:0004779 ! sulfate adenylyltransferase activity + +[Term] +id: GO:0004782 +name: sulfinoalanine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2." [EC:4.1.1.29] +synonym: "3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)" EXACT [EC:4.1.1.29] +synonym: "3-sulfino-L-alanine carboxy-lyase activity" EXACT [EC:4.1.1.29] +synonym: "CADCase/CSADCase activity" EXACT [EC:4.1.1.29] +synonym: "CSAD" RELATED [EC:4.1.1.29] +synonym: "CSADCase activity" EXACT [EC:4.1.1.29] +synonym: "cysteic decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "cysteine-sulfinate decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "cysteinesulfinate decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "cysteinesulfinic acid decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "L-cysteinesulfinic acid decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "sulfoalanine decarboxylase activity" EXACT [EC:4.1.1.29] +synonym: "sulphinoalanine decarboxylase activity" EXACT [] +xref: EC:4.1.1.29 +xref: MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-1655443 "CSAD decarboxylates 3-sulfinoalanine to hypotaurine" +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004783 +name: sulfite reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+." [EC:1.8.1.2] +synonym: "H2S-NADP oxidoreductase activity" EXACT [EC:1.8.1.2] +synonym: "hydrogen-sulfide:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.2] +synonym: "NADPH-dependent sulfite reductase activity" EXACT [EC:1.8.1.2] +synonym: "NADPH-sulfite reductase activity" EXACT [EC:1.8.1.2] +synonym: "NADPH:sulfite reductase flavoprotein" RELATED [] +synonym: "sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.8.1.2] +synonym: "sulphite reductase (NADPH) activity" EXACT [] +xref: EC:1.8.1.2 +xref: MetaCyc:SULFITE-REDUCT-RXN +xref: RHEA:13801 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0004784 +name: superoxide dismutase activity +namespace: molecular_function +alt_id: GO:0004785 +alt_id: GO:0008382 +alt_id: GO:0008383 +alt_id: GO:0016954 +def: "Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide." [EC:1.15.1.1, GOC:vw, PMID:15064408] +synonym: "copper, zinc superoxide dismutase activity" NARROW [] +synonym: "Cu,Zn-SOD" RELATED [EC:1.15.1.1] +synonym: "Cu-Zn superoxide dismutase activity" NARROW [EC:1.15.1.1] +synonym: "cuprein" RELATED [EC:1.15.1.1] +synonym: "cytocuprein" RELATED [EC:1.15.1.1] +synonym: "erythrocuprein" RELATED [EC:1.15.1.1] +synonym: "Fe-SOD" RELATED [EC:1.15.1.1] +synonym: "ferrisuperoxide dismutase activity" NARROW [EC:1.15.1.1] +synonym: "hemocuprein" RELATED [EC:1.15.1.1] +synonym: "hepatocuprein" RELATED [EC:1.15.1.1] +synonym: "iron superoxide dismutase activity" NARROW [] +synonym: "iron superoxide oxidoreductase" RELATED [] +synonym: "manganese superoxide dismutase activity" NARROW [] +synonym: "manganese superoxide oxidoreductase" RELATED [] +synonym: "Mn, Fe superoxide dismutase" NARROW [] +synonym: "Mn-SOD" RELATED [EC:1.15.1.1] +synonym: "nickel superoxide dismutase activity" NARROW [] +synonym: "nickel superoxide oxidoreductase" RELATED [] +synonym: "SOD" RELATED [EC:1.15.1.1] +synonym: "SOD-1" RELATED [EC:1.15.1.1] +synonym: "SOD-2" RELATED [EC:1.15.1.1] +synonym: "SOD-3" RELATED [EC:1.15.1.1] +synonym: "SOD-4" RELATED [EC:1.15.1.1] +synonym: "SODF" RELATED [EC:1.15.1.1] +synonym: "SODS" RELATED [EC:1.15.1.1] +synonym: "superoxide dismutase I" RELATED [EC:1.15.1.1] +synonym: "superoxide dismutase II" RELATED [EC:1.15.1.1] +synonym: "superoxide:superoxide oxidoreductase activity" EXACT [] +synonym: "zinc superoxide oxidoreductase" RELATED [] +xref: EC:1.15.1.1 +xref: MetaCyc:SUPEROX-DISMUT-RXN +xref: Reactome:R-HSA-1222462 "SodB reduces superoxide to H2O2" +xref: Reactome:R-HSA-1222469 "SodC reduces superoxide to H2O2" +xref: Reactome:R-HSA-3299680 "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)" +xref: Reactome:R-HSA-3299682 "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)" +xref: Reactome:R-HSA-3299691 "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)" +xref: Reactome:R-HSA-3777112 "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)" +xref: RHEA:20696 +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor +relationship: part_of GO:0019430 ! removal of superoxide radicals + +[Term] +id: GO:0004786 +name: obsolete Mn, Fe superoxide dismutase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the function is covered by an existing term. +synonym: "Mn, Fe superoxide dismutase" EXACT [] +is_obsolete: true +consider: GO:0004784 + +[Term] +id: GO:0004787 +name: thiamine-pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: TDP + H2O = TMP + phosphate." [EC:3.6.1.-, GOC:ai] +synonym: "thiamin pyrophosphatase activity" EXACT [] +synonym: "thiamin-pyrophosphatase activity" EXACT [] +synonym: "thiamine pyrophosphatase activity" EXACT [] +synonym: "thiaminpyrophosphatase activity" EXACT [EC:3.6.1.6] +synonym: "TPPase activity" EXACT [] +xref: EC:3.6.1 +is_a: GO:0017110 ! nucleoside-diphosphatase activity + +[Term] +id: GO:0004788 +name: thiamine diphosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate." [EC:2.7.6.2] +synonym: "ATP:thiamin pyrophosphotransferase activity" EXACT [EC:2.7.6.2] +synonym: "ATP:thiamine diphosphotransferase activity" EXACT [EC:2.7.6.2] +synonym: "thiamin diphosphokinase activity" EXACT [] +synonym: "thiamin pyrophosphokinase activity" EXACT [] +synonym: "thiamin pyrophosphotransferase activity" EXACT [EC:2.7.6.2] +synonym: "thiamin:ATP pyrophosphotransferase activity" EXACT [EC:2.7.6.2] +synonym: "thiamine pyrophosphokinase activity" EXACT [] +synonym: "thiaminokinase activity" EXACT [EC:2.7.6.2] +synonym: "TPTase activity" EXACT [EC:2.7.6.2] +xref: EC:2.7.6.2 +xref: MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN +xref: Reactome:R-HSA-196761 "2xTPK1:Mg2+ phosphorylates THMN" +xref: RHEA:11576 +is_a: GO:0016778 ! diphosphotransferase activity + +[Term] +id: GO:0004789 +name: thiamine-phosphate diphosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate." [EC:2.5.1.3, RHEA:22328] +synonym: "2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.3] +synonym: "thiamin-phosphate diphosphorylase activity" EXACT [] +synonym: "thiamin-phosphate pyrophosphorylase activity" EXACT [] +synonym: "thiamine monophosphate pyrophosphorylase activity" EXACT [EC:2.5.1.3] +synonym: "thiamine phosphate pyrophosphorylase activity" EXACT [EC:2.5.1.3] +synonym: "thiamine-phosphate pyrophosphorylase activity" EXACT [] +synonym: "thiamine-phosphate synthase activity" EXACT [EC:2.5.1.3] +synonym: "TMP diphosphorylase activity" EXACT [EC:2.5.1.3] +synonym: "TMP pyrophosphorylase activity" EXACT [EC:2.5.1.3] +synonym: "TMP-PPase activity" EXACT [EC:2.5.1.3] +xref: EC:2.5.1.3 +xref: KEGG_REACTION:R03223 +xref: MetaCyc:THI-P-SYN-RXN +xref: RHEA:22328 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0004790 +name: thioether S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium." [EC:2.1.1.96, RHEA:19613] +synonym: "S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity" EXACT [EC:2.1.1.96] +synonym: "S-adenosyl-L-methionine:thioether S-methyltransferase activity" EXACT [EC:2.1.1.96] +synonym: "thioether methyltransferase activity" EXACT [EC:2.1.1.96] +xref: EC:2.1.1.96 +xref: KEGG_REACTION:R02572 +xref: MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN +xref: RHEA:19613 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004791 +name: thioredoxin-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide." [EC:1.8.1.9, RHEA:20345] +synonym: "NADP--thioredoxin reductase activity" EXACT [EC:1.8.1.9] +synonym: "NADPH--thioredoxin reductase activity" EXACT [EC:1.8.1.9] +synonym: "NADPH2:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9] +synonym: "NADPH:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9] +synonym: "thioredoxin disulfide reductase activity" EXACT [] +synonym: "thioredoxin reductase (NADPH) activity" EXACT [] +synonym: "thioredoxin-disulphide reductase activity" EXACT [] +synonym: "thioredoxin:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.9] +xref: EC:1.8.1.9 +xref: KEGG_REACTION:R02016 +xref: MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN +xref: Reactome:R-HSA-1222485 "TrxB reactivates TrxA" +xref: Reactome:R-HSA-3323050 "TXNRD2 catalyzes the reduction of TXN2 by NADPH" +xref: Reactome:R-HSA-73646 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+" +xref: Reactome:R-HSA-9617735 "TXN disrupts FOXO4 complex with EP300" +xref: RHEA:20345 +is_a: GO:0015036 ! disulfide oxidoreductase activity +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0004792 +name: thiosulfate sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate." [EC:2.8.1.1, RHEA:16881] +synonym: "rhodanase activity" EXACT [EC:2.8.1.1] +synonym: "rhodanese activity" RELATED [EC:2.8.1.1] +synonym: "thiosulfate cyanide transsulfurase activity" EXACT [EC:2.8.1.1] +synonym: "thiosulfate thiotransferase activity" EXACT [EC:2.8.1.1] +synonym: "thiosulfate:cyanide sulfurtransferase activity" EXACT [EC:2.8.1.1] +synonym: "thiosulphate sulphurtransferase activity" EXACT [] +xref: EC:2.8.1.1 +xref: KEGG_REACTION:R01931 +xref: MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN +xref: Reactome:R-HSA-9013198 "TST transfers sulfur from S2O3(2-) to HCN to form HSCN" +xref: RHEA:16881 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0004793 +name: threonine aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine = glycine + acetaldehyde." [EC:4.1.2.5] +synonym: "L-threonine acetaldehyde-lyase (glycine-forming)" EXACT [EC:4.1.2.5] +synonym: "L-threonine acetaldehyde-lyase activity" EXACT [EC:4.1.2.5] +synonym: "L-threonine aldolase activity" EXACT [] +xref: EC:4.1.2.5 +xref: MetaCyc:THREONINE-ALDOLASE-RXN +xref: RHEA:19625 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0004794 +name: L-threonine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3." [EC:4.3.1.19] +comment: Note that this function was formerly EC:4.2.1.16. +synonym: "L-serine dehydratase activity" RELATED [EC:4.3.1.19] +synonym: "L-threonine ammonia-lyase (2-oxobutanoate-forming)" EXACT [EC:4.3.1.19] +synonym: "L-threonine deaminase activity" EXACT [EC:4.3.1.19] +synonym: "L-threonine dehydratase activity" EXACT [EC:4.3.1.19] +synonym: "L-threonine hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.19] +synonym: "serine deaminase activity" RELATED [EC:4.3.1.19] +synonym: "threonine ammonia-lyase activity" EXACT [] +synonym: "threonine deaminase activity" EXACT [EC:4.3.1.19] +synonym: "threonine dehydrase activity" EXACT [EC:4.3.1.19] +synonym: "threonine dehydratase activity" EXACT [] +xref: EC:4.3.1.19 +xref: MetaCyc:THREDEHYD-RXN +xref: RHEA:22108 +xref: UM-BBD_reactionID:r0433 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0004795 +name: threonine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate." [EC:4.2.3.1] +synonym: "O-phospho-L-homoserine phospho-lyase (adding water)" EXACT [EC:4.2.3.1] +synonym: "O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming)" EXACT [EC:4.2.3.1] +synonym: "threonine synthetase activity" EXACT [EC:4.2.3.1] +xref: EC:4.2.3.1 +xref: MetaCyc:THRESYN-RXN +xref: RHEA:10840 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0004796 +name: thromboxane-A synthase activity +namespace: molecular_function +alt_id: GO:0008400 +def: "Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2)." [EC:5.3.99.5, RHEA:17137] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity" EXACT [EC:5.3.99.5] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity" EXACT [EC:5.3.99.5] +synonym: "cytochrome P450 CYP5" NARROW [] +synonym: "thromboxane synthase activity" EXACT [EC:5.3.99.5] +synonym: "thromboxane synthetase activity" EXACT [EC:5.3.99.5] +xref: EC:5.3.99.5 +xref: KEGG_REACTION:R02268 +xref: MetaCyc:THROMBOXANE-A-SYNTHASE-RXN +xref: Reactome:R-HSA-5603275 "Defective TBXAS1 does not isomerise PGH2 to TXA2" +xref: Reactome:R-HSA-76500 "TBXAS1 isomerises PGH2 to TXA2" +xref: RHEA:17137 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0004797 +name: thymidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate." [EC:2.7.1.21] +synonym: "2'-deoxythymidine kinase activity" EXACT [EC:2.7.1.21] +synonym: "ATP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.21] +synonym: "deoxythymidine kinase (phosphorylating)" EXACT [EC:2.7.1.21] +synonym: "thymidine kinase (phosphorylating)" EXACT [EC:2.7.1.21] +xref: EC:2.7.1.21 +xref: MetaCyc:THYKI-RXN +xref: RHEA:19129 +is_a: GO:0019136 ! deoxynucleoside kinase activity + +[Term] +id: GO:0004798 +name: thymidylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate." [EC:2.7.4.9] +synonym: "ATP:dTMP phosphotransferase activity" EXACT [EC:2.7.4.9] +synonym: "deoxythymidine 5'-monophosphate kinase activity" EXACT [EC:2.7.4.9] +synonym: "dTMP kinase activity" EXACT [] +synonym: "thymidine 5'-monophosphate kinase activity" EXACT [EC:2.7.4.9] +synonym: "thymidine monophosphate kinase activity" EXACT [EC:2.7.4.9] +synonym: "thymidylate monophosphate kinase activity" EXACT [EC:2.7.4.9] +synonym: "thymidylic acid kinase activity" EXACT [EC:2.7.4.9] +synonym: "thymidylic kinase activity" EXACT [EC:2.7.4.9] +synonym: "TMPK activity" EXACT [EC:2.7.4.9] +xref: EC:2.7.4.9 +xref: MetaCyc:DTMPKI-RXN +xref: RHEA:13517 +is_a: GO:0050145 ! nucleoside monophosphate kinase activity + +[Term] +id: GO:0004799 +name: thymidylate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate." [EC:2.1.1.45, RHEA:12104] +synonym: "5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.45] +synonym: "dTMP synthase activity" EXACT [EC:2.1.1.45] +synonym: "methylenetetrahydrofolate:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.45] +synonym: "thymidylate synthetase activity" EXACT [EC:2.1.1.45] +synonym: "TMP synthetase activity" EXACT [EC:2.1.1.45] +xref: EC:2.1.1.45 +xref: KEGG_REACTION:R02101 +xref: MetaCyc:THYMIDYLATESYN-RXN +xref: Reactome:R-HSA-73605 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate" +xref: RHEA:12104 +is_a: GO:0042083 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity + +[Term] +id: GO:0004800 +name: thyroxine 5'-deiodinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2." [EC:1.21.99.4] +comment: Note that this was EC:3.8.1.4. +synonym: "acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)" EXACT [EC:1.21.99.4] +synonym: "diiodothyronine 5'-deiodinase activity" EXACT [EC:1.21.99.4] +synonym: "iodothyronine 5'-deiodinase activity" EXACT [EC:1.21.99.4] +synonym: "iodothyronine outer ring monodeiodinase activity" EXACT [EC:1.21.99.4] +synonym: "L-thyroxine iodohydrolase (reducing) activity" EXACT [EC:1.21.99.4] +synonym: "outer ring-deiodinating pathway" EXACT [PMID:20403357] +synonym: "thyroxine 5' deiodinase activity" EXACT [] +synonym: "thyroxine deiodinase activity" BROAD [] +synonym: "type I iodothyronine deiodinase activity" NARROW [EC:1.21.99.4] +synonym: "type II iodothyronine deiodinase activity" NARROW [EC:1.21.99.4] +xref: EC:1.21.99.4 +xref: MetaCyc:THYROXINE-DEIODINASE-RXN +xref: Reactome:R-HSA-209772 "Thyroxine is deiodinated to triiodothyronine" +xref: Reactome:R-HSA-350869 "Thyroxine is deiodinated to reverse triiodothyronine (RT3)" +xref: RHEA:19745 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0004801 +name: sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate." [EC:2.2.1.2] +synonym: "dihydroxyacetone transferase activity" BROAD [EC:2.2.1.2] +synonym: "dihydroxyacetonetransferase activity" BROAD [EC:2.2.1.2] +synonym: "glycerone transferase activity" BROAD [EC:2.2.1.2] +synonym: "transaldolase activity" BROAD [EC:2.2.1.2] +xref: EC:2.2.1.2 +xref: MetaCyc:TRANSALDOL-RXN +xref: Reactome:R-HSA-163764 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate" +xref: Reactome:R-HSA-5659989 "Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P" +xref: Reactome:R-HSA-5659998 "Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P" +xref: Reactome:R-HSA-71334 "sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate" +xref: RHEA:17053 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0004802 +name: transketolase activity +namespace: molecular_function +def: "Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor." [EC:2.2.1.1, GOC:fmc] +synonym: "fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity" NARROW [GOC:fmc, GOC:mah] +synonym: "glycoaldehyde transferase activity" EXACT [EC:2.2.1.1] +synonym: "glycolaldehydetransferase activity" EXACT [EC:2.2.1.1] +synonym: "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity" NARROW [EC:2.2.1.1] +xref: EC:2.2.1.1 +xref: MetaCyc:1TRANSKETO-RXN +xref: Reactome:R-HSA-163741 "D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate" +xref: Reactome:R-HSA-163751 "D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate" +xref: Reactome:R-HSA-71324 "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate" +xref: Reactome:R-HSA-71335 "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate" +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0004803 +name: transposase activity +namespace: molecular_function +alt_id: GO:0004804 +def: "Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element." [GOC:bm, ISBN:0198506732] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "P-element encoded transposase activity" NARROW [] +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0004805 +name: trehalose-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate." [EC:3.1.3.12] +synonym: "trehalose 6-phosphatase activity" EXACT [EC:3.1.3.12] +synonym: "trehalose 6-phosphate phosphatase activity" EXACT [EC:3.1.3.12] +synonym: "trehalose phosphatase activity" EXACT [] +synonym: "trehalose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.12] +xref: EC:3.1.3.12 +xref: MetaCyc:TREHALOSEPHOSPHA-RXN +xref: RHEA:23420 +is_a: GO:0019203 ! carbohydrate phosphatase activity + +[Term] +id: GO:0004806 +name: triglyceride lipase activity +namespace: molecular_function +def: "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate." [EC:3.1.1.3] +subset: goslim_chembl +synonym: "amano AP" RELATED [EC:3.1.1.3] +synonym: "amano B" RELATED [EC:3.1.1.3] +synonym: "amano CE" RELATED [EC:3.1.1.3] +synonym: "amano CES" RELATED [EC:3.1.1.3] +synonym: "amano P" RELATED [EC:3.1.1.3] +synonym: "amno N-AP" RELATED [EC:3.1.1.3] +synonym: "butyrinase activity" EXACT [EC:3.1.1.3] +synonym: "cacordase activity" EXACT [EC:3.1.1.3] +synonym: "capalase L" RELATED [EC:3.1.1.3] +synonym: "GA 56" RELATED [EC:3.1.1.3] +synonym: "GEH" RELATED [EC:3.1.1.3] +synonym: "glycerol ester hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "glycerol-ester hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "heparin releasable hepatic lipase" NARROW [EC:3.1.1.3] +synonym: "hepatic lipase" NARROW [EC:3.1.1.3] +synonym: "hepatic monoacylglycerol acyltransferase" NARROW [EC:3.1.1.3] +synonym: "lipazin" RELATED [EC:3.1.1.3] +synonym: "liver lipase" NARROW [EC:3.1.1.3] +synonym: "meito MY 30" RELATED [EC:3.1.1.3] +synonym: "meito sangyo OF lipase" RELATED [EC:3.1.1.3] +synonym: "post-heparin plasma protamine-resistant lipase" NARROW [EC:3.1.1.3] +synonym: "PPL" RELATED [EC:3.1.1.3] +synonym: "salt-resistant post-heparin lipase" NARROW [EC:3.1.1.3] +synonym: "steapsin" RELATED [EC:3.1.1.3] +synonym: "TAG activity" EXACT [PMID:16054079] +synonym: "takedo 1969-4-9" RELATED [EC:3.1.1.3] +synonym: "triacetinase activity" EXACT [EC:3.1.1.3] +synonym: "triacylglycerol acylhydrolase activity" EXACT [EC:3.1.1.3] +synonym: "triacylglycerol ester hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "triacylglycerol lipase activity" EXACT [EC:3.1.1.3] +synonym: "tributyrase activity" RELATED [EC:3.1.1.3] +synonym: "tributyrin esterase activity" EXACT [EC:3.1.1.3] +synonym: "tributyrinase activity" EXACT [EC:3.1.1.3] +synonym: "triglyceridase activity" EXACT [EC:3.1.1.3] +synonym: "triglyceride hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "triolein hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "tween hydrolase activity" EXACT [EC:3.1.1.3] +synonym: "tween-hydrolyzing esterase activity" EXACT [EC:3.1.1.3] +synonym: "tweenase activity" EXACT [EC:3.1.1.3] +synonym: "tweenesterase activity" EXACT [EC:3.1.1.3] +xref: EC:3.1.1.3 +xref: MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN +xref: Reactome:R-HSA-1482777 "TAG is hydrolyzed to DAG by PNPLA2/3" +xref: Reactome:R-HSA-163551 "triacylglycerol + H2O -> diacylglycerol + fatty acid" +xref: Reactome:R-HSA-5694109 "LIPC dimer hydrolyses TAG to DAG and FA" +xref: Reactome:R-HSA-8848338 "PNPLA4 hydrolyzes TAG" +xref: Reactome:R-HSA-8848339 "PNPLA5 hydrolyzes TAG" +xref: RHEA:12044 +is_a: GO:0016298 ! lipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0004807 +name: triose-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate." [EC:5.3.1.1, RHEA:18585] +synonym: "D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.1] +synonym: "D-glyceraldehyde-3-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.1] +synonym: "phosphotriose isomerase activity" EXACT [EC:5.3.1.1] +synonym: "triose phosphate mutase activity" EXACT [EC:5.3.1.1] +synonym: "triose phosphoisomerase activity" EXACT [EC:5.3.1.1] +synonym: "triosephosphate isomerase activity" EXACT [EC:5.3.1.1] +synonym: "triosephosphate mutase activity" EXACT [EC:5.3.1.1] +xref: EC:5.3.1.1 +xref: KEGG_REACTION:R01015 +xref: MetaCyc:TRIOSEPISOMERIZATION-RXN +xref: Reactome:R-HSA-70454 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate" +xref: Reactome:R-HSA-70481 "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate" +xref: RHEA:18585 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0004808 +name: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity +namespace: molecular_function +alt_id: GO:0016425 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate." [EC:2.1.1.61, GOC:imk] +synonym: "S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity" EXACT [EC:2.1.1.61] +synonym: "transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity" EXACT [EC:2.1.1.61] +synonym: "tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity" EXACT [EC:2.1.1.61] +xref: EC:2.1.1.61 +xref: KEGG_REACTION:R00601 +xref: MetaCyc:2.1.1.61-RXN +is_a: GO:0008175 ! tRNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004809 +name: tRNA (guanine-N2-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine." [EC:2.1.1.32] +synonym: "guanine-N2-methylase activity" EXACT [EC:2.1.1.32] +synonym: "N(2),N(2)-dimethylguanine tRNA methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "N2,N2-dimethylguanine tRNA methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "transfer ribonucleate guanine 2-methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "transfer ribonucleate guanine N2-methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "transfer RNA guanine 2-methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "tRNA 2,2-dimethylguanosine-26 methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "tRNA(guanine-26,N(2)-N(2)) methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "tRNA(guanine-26,N2-N2) methyltransferase activity" EXACT [EC:2.1.1.32] +synonym: "tRNA(m(2,2)G26)dimethyltransferase activity" EXACT [EC:2.1.1.32] +xref: Reactome:R-HSA-6782416 "TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr)" +xref: Reactome:R-HSA-6786501 "TRMT11:TRMT112 methylates guanosine-10 in tRNA" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity + +[Term] +id: GO:0004810 +name: tRNA adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1)." [EC:2.7.7.25] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "-C-C-A pyrophosphorylase" BROAD [EC:2.7.7.25] +synonym: "ATP (CTP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "ATP(CTP)-tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "ATP:tRNA adenylyltransferase activity" EXACT [] +synonym: "CCA-adding enzyme activity" RELATED [EC:2.7.7.25] +synonym: "CTP(ATP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase" BROAD [EC:2.7.7.25] +synonym: "ribonucleic cytidylyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleate adenyltransferase activity" EXACT [EC:2.7.7.25] +synonym: "transfer ribonucleate adenylyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleate cytidylyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleate nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleic acid nucleotidyl transferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleic adenylyl (cytidylyl) transferase" BROAD [EC:2.7.7.25] +synonym: "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer RNA adenylyltransferase" BROAD [EC:2.7.7.25] +synonym: "transfer-RNA nucleotidyltransferase" BROAD [EC:2.7.7.25] +synonym: "tRNA adenylyl(cytidylyl)transferase" BROAD [EC:2.7.7.25] +synonym: "tRNA CCA-diphosphorylase activity" RELATED [EC:2.7.7.25] +synonym: "tRNA CCA-pyrophosphorylase activity" RELATED [EC:2.7.7.25] +synonym: "tRNA-nucleotidyltransferase activity" BROAD [EC:2.7.7.25] +xref: EC:2.7.7.25 +xref: MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN +is_a: GO:1990817 ! RNA adenylyltransferase activity + +[Term] +id: GO:0004812 +name: aminoacyl-tRNA ligase activity +namespace: molecular_function +alt_id: GO:0016876 +alt_id: GO:0017100 +def: "Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP." [ISBN:0198506732] +comment: Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA. +synonym: "aminoacyl-tRNA synthetase activity" EXACT [GOC:hjd] +synonym: "aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [] +synonym: "ligase activity, forming aminoacyl-tRNA and related compounds" BROAD [] +xref: EC:6.1.1 +is_a: GO:0016875 ! ligase activity, forming carbon-oxygen bonds +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0004813 +name: alanine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)." [EC:6.1.1.7] +synonym: "Ala-tRNA synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanine transfer RNA synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanine translase activity" EXACT [EC:6.1.1.7] +synonym: "alanine tRNA synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanine-transfer RNA ligase activity" EXACT [EC:6.1.1.7] +synonym: "alanyl-transfer ribonucleate synthase activity" EXACT [EC:6.1.1.7] +synonym: "alanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.7] +synonym: "alanyl-tRNA synthetase activity" EXACT [] +synonym: "AlaRS" RELATED [EC:6.1.1.7] +synonym: "L-alanine:tRNAAla ligase (AMP-forming)" EXACT [EC:6.1.1.7] +xref: EC:6.1.1.7 +xref: MetaCyc:ALANINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379864 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380177 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate" +xref: RHEA:12540 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004814 +name: arginine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)." [EC:6.1.1.19] +synonym: "arginine translase activity" EXACT [EC:6.1.1.19] +synonym: "arginine-tRNA synthetase activity" EXACT [EC:6.1.1.19] +synonym: "arginyl transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.19] +synonym: "arginyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.19] +synonym: "arginyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.19] +synonym: "arginyl-tRNA synthetase activity" EXACT [] +synonym: "L-arginine:tRNAArg ligase (AMP-forming)" EXACT [EC:6.1.1.19] +xref: EC:6.1.1.19 +xref: MetaCyc:ARGININE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379993 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380224 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate" +xref: RHEA:20301 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004815 +name: aspartate-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)." [EC:6.1.1.12] +synonym: "aspartic acid translase activity" EXACT [EC:6.1.1.12] +synonym: "aspartyl ribonucleate synthetase activity" EXACT [EC:6.1.1.12] +synonym: "aspartyl ribonucleic synthetase activity" EXACT [EC:6.1.1.12] +synonym: "aspartyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.12] +synonym: "aspartyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.12] +synonym: "aspartyl-tRNA synthetase activity" EXACT [] +synonym: "L-aspartate:tRNAAsp ligase (AMP-forming)" EXACT [EC:6.1.1.12] +xref: EC:6.1.1.12 +xref: MetaCyc:ASPARTATE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379867 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380229 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate" +xref: RHEA:19649 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004816 +name: asparagine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+)." [EC:6.1.1.22, RHEA:11180] +synonym: "asparagine translase activity" EXACT [EC:6.1.1.22] +synonym: "asparaginyl transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.22] +synonym: "asparaginyl transfer RNA synthetase activity" EXACT [EC:6.1.1.22] +synonym: "asparaginyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.22] +synonym: "asparaginyl-tRNA synthetase activity" EXACT [] +synonym: "asparagyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.22] +synonym: "L-asparagine:tRNAAsn ligase (AMP-forming)" EXACT [EC:6.1.1.22] +xref: EC:6.1.1.22 +xref: KEGG_REACTION:R03648 +xref: MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379996 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380227 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate" +xref: RHEA:11180 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004817 +name: cysteine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)." [EC:6.1.1.16] +synonym: "cysteine translase activity" EXACT [EC:6.1.1.16] +synonym: "cysteinyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.16] +synonym: "cysteinyl-transferRNA synthetase activity" EXACT [EC:6.1.1.16] +synonym: "cysteinyl-tRNA synthetase activity" EXACT [] +synonym: "L-cysteine:tRNACys ligase (AMP-forming)" EXACT [EC:6.1.1.16] +xref: EC:6.1.1.16 +xref: MetaCyc:CYSTEINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379887 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380158 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate" +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004818 +name: glutamate-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)." [EC:6.1.1.17] +synonym: "glutamate-tRNA synthetase activity" EXACT [EC:6.1.1.17] +synonym: "glutamic acid translase activity" EXACT [EC:6.1.1.17] +synonym: "glutamyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.17] +synonym: "glutamyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.17] +synonym: "glutamyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.17] +synonym: "glutamyl-tRNA synthetase activity" EXACT [] +synonym: "L-glutamate:tRNAGlu ligase (AMP-forming) activity" EXACT [EC:6.1.1.17] +xref: EC:6.1.1.17 +xref: MetaCyc:GLURS-RXN +xref: Reactome:R-HSA-379861 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380216 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate" +xref: RHEA:23540 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004819 +name: glutamine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)." [EC:6.1.1.18] +synonym: "GlnRS" RELATED [EC:6.1.1.18] +synonym: "glutamine translase activity" EXACT [EC:6.1.1.18] +synonym: "glutamine-tRNA synthetase activity" EXACT [EC:6.1.1.18] +synonym: "glutaminyl ribonucleic acid" RELATED [EC:6.1.1.18] +synonym: "glutaminyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.18] +synonym: "glutaminyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.18] +synonym: "glutaminyl-tRNA synthetase activity" EXACT [] +synonym: "L-glutamine:tRNAGln ligase (AMP-forming)" EXACT [EC:6.1.1.18] +xref: EC:6.1.1.18 +xref: MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379982 "glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380241 "glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate" +xref: RHEA:20121 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004820 +name: glycine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)." [EC:6.1.1.14] +synonym: "glycine:tRNAGly ligase (AMP-forming) activity" EXACT [EC:6.1.1.14] +synonym: "glycyl translase activity" EXACT [EC:6.1.1.14] +synonym: "glycyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.14] +synonym: "glycyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.14] +synonym: "glycyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.14] +synonym: "glycyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.14 +xref: MetaCyc:GLYCINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-380048 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380240 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate" +xref: RHEA:16013 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004821 +name: histidine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His)." [EC:6.1.1.21] +synonym: "histidine translase activity" EXACT [EC:6.1.1.21] +synonym: "histidyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.21] +synonym: "histidyl-tRNA synthetase activity" EXACT [] +synonym: "L-histidine:tRNAHis ligase (AMP-forming)" EXACT [EC:6.1.1.21] +xref: EC:6.1.1.21 +xref: MetaCyc:HISTIDINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379844 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380234 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate" +xref: RHEA:17313 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004822 +name: isoleucine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+)." [EC:6.1.1.5, RHEA:11060] +synonym: "isoleucine translase activity" EXACT [EC:6.1.1.5] +synonym: "isoleucine-transfer RNA ligase activity" EXACT [EC:6.1.1.5] +synonym: "isoleucine-tRNA synthetase activity" EXACT [EC:6.1.1.5] +synonym: "isoleucyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.5] +synonym: "isoleucyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.5] +synonym: "isoleucyl-tRNA synthetase activity" EXACT [] +synonym: "L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [EC:6.1.1.5] +xref: EC:6.1.1.5 +xref: KEGG_REACTION:R03656 +xref: MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379893 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380176 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate" +xref: RHEA:11060 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004823 +name: leucine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu)." [EC:6.1.1.4, RHEA:11688] +synonym: "L-leucine:tRNALeu ligase (AMP-forming)" EXACT [EC:6.1.1.4] +synonym: "leucine translase activity" EXACT [EC:6.1.1.4] +synonym: "leucine-tRNA synthetase activity" EXACT [EC:6.1.1.4] +synonym: "leucyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.4] +synonym: "leucyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.4] +synonym: "leucyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.4] +synonym: "leucyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.4 +xref: KEGG_REACTION:R03657 +xref: MetaCyc:LEUCINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379974 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380200 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate" +xref: RHEA:11688 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004824 +name: lysine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)." [EC:6.1.1.6] +synonym: "L-lysine-transfer RNA ligase activity" EXACT [EC:6.1.1.6] +synonym: "L-lysine:tRNALys ligase (AMP-forming)" EXACT [EC:6.1.1.6] +synonym: "lysine translase activity" EXACT [EC:6.1.1.6] +synonym: "lysine-tRNA synthetase activity" EXACT [EC:6.1.1.6] +synonym: "lysyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.6] +synonym: "lysyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.6] +synonym: "lysyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.6 +xref: MetaCyc:LYSINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-380008 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380233 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate" +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004825 +name: methionine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)." [EC:6.1.1.10] +synonym: "L-methionine:tRNAMet ligase (AMP-forming)" EXACT [EC:6.1.1.10] +synonym: "methionine translase activity" EXACT [EC:6.1.1.10] +synonym: "methionyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.10] +synonym: "methionyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.10] +synonym: "methionyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.10] +synonym: "methionyl-tRNA synthetase activity" EXACT [] +synonym: "MetRS activity" EXACT [EC:6.1.1.10] +xref: EC:6.1.1.10 +xref: MetaCyc:METHIONINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379994 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380157 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate" +xref: RHEA:13481 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004826 +name: phenylalanine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)." [EC:6.1.1.20] +synonym: "L-phenylalanine:tRNAPhe ligase (AMP-forming) activity" EXACT [EC:6.1.1.20] +synonym: "L-phenylalanyl-tRNA synthetase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanine translase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanine-tRNA synthetase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanyl-transfer RNA ligase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanyl-tRNA ligase activity" EXACT [EC:6.1.1.20] +synonym: "phenylalanyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.20 +xref: MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379848 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380203 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate" +xref: RHEA:19413 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004827 +name: proline-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)." [EC:6.1.1.15] +synonym: "L-proline:tRNAPro ligase (AMP-forming)" EXACT [EC:6.1.1.15] +synonym: "proline translase activity" EXACT [EC:6.1.1.15] +synonym: "prolinyl-tRNA ligase activity" EXACT [EC:6.1.1.15] +synonym: "prolyl-s-RNA synthetase activity" EXACT [EC:6.1.1.15] +synonym: "prolyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.15] +synonym: "prolyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.15] +synonym: "prolyl-transferRNA synthetase activity" EXACT [EC:6.1.1.15] +synonym: "prolyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.15 +xref: MetaCyc:PROLINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379865 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380198 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate" +xref: RHEA:14305 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004828 +name: serine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser)." [EC:6.1.1.11] +synonym: "L-serine:tRNASer ligase (AMP-forming)" EXACT [EC:6.1.1.11] +synonym: "serine translase activity" EXACT [EC:6.1.1.11] +synonym: "SerRS activity" EXACT [EC:6.1.1.11] +synonym: "seryl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.11] +synonym: "seryl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.11] +synonym: "seryl-transfer RNA synthetase activity" EXACT [EC:6.1.1.11] +synonym: "seryl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.11 +xref: MetaCyc:SERINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379992 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380239 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate" +xref: RHEA:12292 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004829 +name: threonine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)." [EC:6.1.1.3] +synonym: "L-threonine:tRNAThr ligase (AMP-forming)" EXACT [EC:6.1.1.3] +synonym: "threonine translase activity" EXACT [EC:6.1.1.3] +synonym: "threonine-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.3] +synonym: "threonyl ribonucleic synthetase activity" EXACT [EC:6.1.1.3] +synonym: "threonyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.3] +synonym: "threonyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.3] +synonym: "threonyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.3] +synonym: "threonyl-tRNA synthetase activity" EXACT [] +synonym: "TRS" RELATED [EC:6.1.1.3] +xref: EC:6.1.1.3 +xref: MetaCyc:THREONINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-380002 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380201 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate" +xref: RHEA:24624 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004830 +name: tryptophan-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp)." [EC:6.1.1.2] +synonym: "L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity" EXACT [EC:6.1.1.2] +synonym: "L-tryptophan-tRNATrp ligase (AMP-forming)" EXACT [EC:6.1.1.2] +synonym: "L-tryptophan:tRNATrp ligase (AMP-forming)" EXACT [EC:6.1.1.2] +synonym: "TrpRS activity" EXACT [EC:6.1.1.2] +synonym: "tryptophan translase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl ribonucleic synthetase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-transfer ribonucleic synthetase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-tRNA synthase activity" EXACT [EC:6.1.1.2] +synonym: "tryptophanyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.2 +xref: MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379977 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380222 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate" +xref: RHEA:24080 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004831 +name: tyrosine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+)." [EC:6.1.1.1, RHEA:10220] +synonym: "L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity" EXACT [EC:6.1.1.1] +synonym: "L-tyrosine-tRNATyr ligase (AMP-forming)" EXACT [EC:6.1.1.1] +synonym: "L-tyrosine:tRNATyr ligase (AMP-forming)" EXACT [EC:6.1.1.1] +synonym: "tyrosine translase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosine tRNA synthetase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosine-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosine-transfer RNA ligase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosyl-tRNA ligase activity" EXACT [EC:6.1.1.1] +synonym: "tyrosyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.1 +xref: KEGG_REACTION:R02918 +xref: MetaCyc:TYROSINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-379980 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380170 "tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate" +xref: RHEA:10220 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004832 +name: valine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+)." [EC:6.1.1.9, RHEA:10704] +synonym: "L-valine:tRNAVal ligase (AMP-forming)" EXACT [EC:6.1.1.9] +synonym: "valine transfer ribonucleate ligase activity" EXACT [EC:6.1.1.9] +synonym: "valine translase activity" EXACT [EC:6.1.1.9] +synonym: "valyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.9] +synonym: "valyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.9] +synonym: "valyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.9] +synonym: "valyl-tRNA synthetase activity" EXACT [] +xref: EC:6.1.1.9 +xref: KEGG_REACTION:R03665 +xref: MetaCyc:VALINE--TRNA-LIGASE-RXN +xref: Reactome:R-HSA-380042 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate" +xref: Reactome:R-HSA-380199 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate" +xref: RHEA:10704 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0004833 +name: tryptophan 2,3-dioxygenase activity +namespace: molecular_function +alt_id: GO:0004426 +def: "Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine." [EC:1.13.11.11] +synonym: "indolamine 2,3-dioxygenase activity" BROAD [EC:1.13.11.11] +synonym: "indoleamine-pyrrole 2,3-dioxygenase activity" EXACT [] +synonym: "L-tryptophan 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] +synonym: "L-tryptophan pyrrolase activity" EXACT [EC:1.13.11.11] +synonym: "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.11] +synonym: "TDO" RELATED [EC:1.13.11.11] +synonym: "tryptamin 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] +synonym: "tryptamine 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] +synonym: "tryptophan oxygenase activity" BROAD [EC:1.13.11.11] +synonym: "tryptophan peroxidase activity" BROAD [EC:1.13.11.11] +synonym: "tryptophan pyrrolase activity" BROAD [EC:1.13.11.11] +xref: EC:1.13.11.11 +xref: MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN +xref: Reactome:R-HSA-198563 "IDO1 dioxygenates L-Trp to NFK" +xref: Reactome:R-HSA-71188 "TDO tetramer dioxygenates L-Trp to NFK" +xref: Reactome:R-HSA-888614 "IDO2 dioxygenates L-Trp to NFK" +xref: RHEA:24536 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0004834 +name: tryptophan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O." [RHEA:10532] +synonym: "indoleglycerol phosphate aldolase activity" EXACT [EC:4.2.1.20] +synonym: "L-serine hydro-lyase (adding indoleglycerol-phosphate)" EXACT [EC:4.2.1.20] +synonym: "L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]" RELATED [EC:4.2.1.20] +synonym: "L-tryptophan synthetase activity" EXACT [EC:4.2.1.20] +synonym: "tryptophan desmolase activity" EXACT [EC:4.2.1.20] +synonym: "tryptophan synthetase activity" EXACT [EC:4.2.1.20] +xref: EC:4.2.1.20 +xref: KEGG_REACTION:R02722 +xref: MetaCyc:TRYPSYN-RXN +xref: RHEA:10532 +is_a: GO:0016836 ! hydro-lyase activity +relationship: part_of GO:0000162 ! tryptophan biosynthetic process + +[Term] +id: GO:0004835 +name: tubulin-tyrosine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate." [EC:6.3.2.25] +synonym: "alpha-tubulin:L-tyrosine ligase (ADP-forming)" EXACT [EC:6.3.2.25] +synonym: "TTL activity" EXACT [EC:6.3.2.25] +synonym: "tubulinyl-tyrosine ligase activity" EXACT [] +xref: EC:6.3.2.25 +xref: MetaCyc:6.3.2.25-RXN +xref: Reactome:R-HSA-8955706 "TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin" +is_a: GO:0016881 ! acid-amino acid ligase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0004836 +name: tyramine-beta hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of tyramine to form octopamine." [PMID:10745161] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0004837 +name: tyrosine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine = tyramine + CO2." [EC:4.1.1.25] +synonym: "L-(-)-tyrosine apodecarboxylase activity" EXACT [EC:4.1.1.25] +synonym: "L-tyrosine carboxy-lyase (tyramine-forming)" EXACT [EC:4.1.1.25] +synonym: "L-tyrosine carboxy-lyase activity" EXACT [EC:4.1.1.25] +synonym: "L-tyrosine decarboxylase activity" EXACT [EC:4.1.1.25] +xref: EC:4.1.1.25 +xref: MetaCyc:TYROSINE-DECARBOXYLASE-RXN +xref: RHEA:14345 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004838 +name: L-tyrosine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate." [EC:2.6.1.5] +synonym: "glutamic phenylpyruvic aminotransferase activity" RELATED [EC:2.6.1.5] +synonym: "glutamic-hydroxyphenylpyruvic transaminase activity" RELATED [EC:2.6.1.5] +synonym: "L-phenylalanine 2-oxoglutarate aminotransferase activity" RELATED [EC:2.6.1.5] +synonym: "L-tyrosine aminotransferase activity" BROAD [EC:2.6.1.5] +synonym: "phenylalanine aminotransferase activity" RELATED [EC:2.6.1.5] +synonym: "phenylalanine transaminase activity" RELATED [EC:2.6.1.5] +synonym: "phenylalanine-alpha-ketoglutarate transaminase activity" RELATED [EC:2.6.1.5] +synonym: "phenylpyruvate transaminase activity" RELATED [EC:2.6.1.5] +synonym: "phenylpyruvic acid transaminase activity" RELATED [EC:2.6.1.5] +synonym: "TyrAT activity" RELATED [EC:2.6.1.5] +synonym: "tyrosine aminotransferase activity" BROAD [] +synonym: "tyrosine transaminase activity" BROAD [EC:2.6.1.5] +synonym: "tyrosine-2-ketoglutarate aminotransferase activity" BROAD [EC:2.6.1.5] +synonym: "tyrosine-alpha-ketoglutarate aminotransferase activity" BROAD [EC:2.6.1.5] +synonym: "tyrosine-alpha-ketoglutarate transaminase activity" BROAD [EC:2.6.1.5] +xref: EC:2.6.1.5 +xref: MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-517444 "p-hydroxyphenylpyruvate + glutamate <=> tyrosine + alpha-ketoglutarate" +xref: Reactome:R-HSA-71155 "tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate" +is_a: GO:0070547 ! L-tyrosine aminotransferase activity + +[Term] +id: GO:0004839 +name: ubiquitin activating enzyme activity +namespace: molecular_function +def: "Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate." [GOC:BioGRID, Wikipedia:Ubiquitin-activating_enzyme] +comment: The ubiquitin activating enzyme catalyzes a ligation reaction. +synonym: "E1 ubiquitin-activating enzyme" EXACT [EC:6.2.1.45] +xref: EC:6.2.1.45 +xref: Reactome:R-HSA-8852132 "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol" +xref: Reactome:R-HSA-8852133 "UBA1 conjugates ubiquitin to UBA1 in the cytosol" +xref: Reactome:R-HSA-8852134 "UBA1 adenylates ubiquitin in the cytosol" +xref: Reactome:R-HSA-8865050 "Ub-Cys625-UBA6 adenylates ubiquitin in the cytosol" +xref: Reactome:R-HSA-8865090 "UBA6 adenylates ubiquitin in the cytosol" +xref: Reactome:R-HSA-8865098 "UBA6 conjugates ubiquitin to UBA6 in the cytosol" +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity +relationship: part_of GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0004842 +name: ubiquitin-protein transferase activity +namespace: molecular_function +alt_id: GO:0004840 +alt_id: GO:0004841 +def: "Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages." [GOC:BioGRID, GOC:jh2, PMID:9635407] +synonym: "anaphase-promoting complex activity" NARROW [GOC:dph, GOC:tb] +synonym: "E2" RELATED [] +synonym: "E3" RELATED [] +synonym: "ubiquitin conjugating enzyme activity" NARROW [] +synonym: "ubiquitin ligase activity" NARROW [] +synonym: "ubiquitin protein ligase activity" NARROW [] +synonym: "ubiquitin protein-ligase activity" NARROW [] +synonym: "ubiquitin-conjugating enzyme activity" NARROW [] +xref: KEGG_REACTION:R03876 +xref: Reactome:R-HSA-1169394 "ISGylation of IRF3" +xref: Reactome:R-HSA-1169395 "ISGylation of viral protein NS1" +xref: Reactome:R-HSA-1169397 "Activation of ISG15 by UBA7 E1 ligase" +xref: Reactome:R-HSA-1169398 "ISGylation of host protein filamin B" +xref: Reactome:R-HSA-1169402 "ISGylation of E2 conjugating enzymes" +xref: Reactome:R-HSA-1169405 "ISGylation of protein phosphatase 1 beta (PP2CB)" +xref: Reactome:R-HSA-1169406 "ISGylation of host proteins" +xref: Reactome:R-HSA-1234163 "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha" +xref: Reactome:R-HSA-1234172 "Nuclear VBC complex ubiquitinylates HIF-alpha" +xref: Reactome:R-HSA-1253282 "ERBB4 ubiquitination by WWP1/ITCH" +xref: Reactome:R-HSA-1358789 "Self-ubiquitination of RNF41" +xref: Reactome:R-HSA-1358790 "RNF41 ubiquitinates ERBB3" +xref: Reactome:R-HSA-1358792 "RNF41 ubiquitinates activated ERBB3" +xref: Reactome:R-HSA-1363331 "Ubiquitination of p130 (RBL2) by SCF (Skp2)" +xref: Reactome:R-HSA-168915 "K63-linked ubiquitination of RIP1 bound to the activated TLR complex" +xref: Reactome:R-HSA-173542 "SMURF2 ubiquitinates SMAD2" +xref: Reactome:R-HSA-173545 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling" +xref: Reactome:R-HSA-174057 "Multiubiquitination of APC/C-associated Cdh1" +xref: Reactome:R-HSA-174104 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex" +xref: Reactome:R-HSA-174144 "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex" +xref: Reactome:R-HSA-174159 "Ubiquitination of Emi1 by SCF-beta-TrCP" +xref: Reactome:R-HSA-174195 "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex" +xref: Reactome:R-HSA-174227 "Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex" +xref: Reactome:R-HSA-179417 "Multiubiquitination of Nek2A" +xref: Reactome:R-HSA-180540 "Multi-ubiquitination of APOBEC3G" +xref: Reactome:R-HSA-180597 "Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex" +xref: Reactome:R-HSA-182986 "CBL-mediated ubiquitination of CIN85" +xref: Reactome:R-HSA-182993 "Ubiquitination of stimulated EGFR (CBL)" +xref: Reactome:R-HSA-183036 "Ubiquitination of stimulated EGFR (CBL:GRB2)" +xref: Reactome:R-HSA-183051 "CBL ubiquitinates Sprouty" +xref: Reactome:R-HSA-183084 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix" +xref: Reactome:R-HSA-183089 "CBL binds and ubiquitinates phosphorylated Sprouty" +xref: Reactome:R-HSA-1852623 "Ubiquitination of NICD1 by FBWX7" +xref: Reactome:R-HSA-187575 "Ubiquitination of phospho-p27/p21" +xref: Reactome:R-HSA-1912357 "ITCH ubiquitinates DTX" +xref: Reactome:R-HSA-1912386 "Ubiquitination of NOTCH1 by ITCH in the absence of ligand" +xref: Reactome:R-HSA-1918092 "CHIP (STUB1) mediates ubiquitination of ERBB2" +xref: Reactome:R-HSA-1918095 "CUL5 mediates ubiquitination of ERBB2" +xref: Reactome:R-HSA-1977296 "NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer" +xref: Reactome:R-HSA-1980074 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH1" +xref: Reactome:R-HSA-1980118 "ARRB mediates NOTCH1 ubiquitination" +xref: Reactome:R-HSA-201425 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling" +xref: Reactome:R-HSA-202453 "Auto-ubiquitination of TRAF6" +xref: Reactome:R-HSA-202534 "Ubiquitination of NEMO by TRAF6" +xref: Reactome:R-HSA-205118 "TRAF6 polyubiquitinates NRIF" +xref: Reactome:R-HSA-209063 "Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex" +xref: Reactome:R-HSA-211734 "Ubiquitination of PAK-2p34" +xref: Reactome:R-HSA-2169050 "SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7" +xref: Reactome:R-HSA-2172172 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH2" +xref: Reactome:R-HSA-2179276 "SMURF2 monoubiquitinates SMAD3" +xref: Reactome:R-HSA-2186747 "Ubiquitination of SKI/SKIL by RNF111/SMURF2" +xref: Reactome:R-HSA-2186785 "RNF111 ubiquitinates SMAD7" +xref: Reactome:R-HSA-2187368 "STUB1 (CHIP) ubiquitinates SMAD3" +xref: Reactome:R-HSA-2213017 "Auto-ubiquitination of TRAF3" +xref: Reactome:R-HSA-264444 "Autoubiquitination of phospho-COP1(Ser-387 )" +xref: Reactome:R-HSA-2682349 "RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels" +xref: Reactome:R-HSA-2730904 "Auto-ubiquitination of TRAF6" +xref: Reactome:R-HSA-2737728 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants" +xref: Reactome:R-HSA-2769007 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 PEST domain mutants" +xref: Reactome:R-HSA-2900765 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants" +xref: Reactome:R-HSA-3000335 "SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA" +xref: Reactome:R-HSA-3134804 "STING ubiquitination by TRIM32 or TRIM56" +xref: Reactome:R-HSA-3134946 "DDX41 ubiquitination by TRIM21" +xref: Reactome:R-HSA-3249386 "DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1" +xref: Reactome:R-HSA-3780995 "NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2" +xref: Reactome:R-HSA-3781009 "NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1" +xref: Reactome:R-HSA-3788724 "Cdh1:APC/C ubiquitinates EHMT1 and EHMT2" +xref: Reactome:R-HSA-3797226 "Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease)" +xref: Reactome:R-HSA-400267 "BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins" +xref: Reactome:R-HSA-4332236 "CBL neddylates TGFBR2" +xref: Reactome:R-HSA-446877 "TRAF6 is K63 poly-ubiquitinated" +xref: Reactome:R-HSA-450358 "Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation" +xref: Reactome:R-HSA-451418 "Pellino ubiquitinates IRAK1" +xref: Reactome:R-HSA-5205682 "Parkin promotes the ubiquitination of mitochondrial substrates" +xref: Reactome:R-HSA-5357757 "BIRC(cIAP1/2) ubiquitinates RIPK1" +xref: Reactome:R-HSA-5362412 "SYVN1 ubiquitinates Hh C-terminal fragments" +xref: Reactome:R-HSA-5483238 "Hh processing variants are ubiquitinated" +xref: Reactome:R-HSA-5607725 "SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP" +xref: Reactome:R-HSA-5607728 "beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex" +xref: Reactome:R-HSA-5607756 "TRAF6 oligomer autoubiquitinates" +xref: Reactome:R-HSA-5607757 "K63polyUb-TRAF6 ubiquitinates TAK1" +xref: Reactome:R-HSA-5610742 "SCF(beta-TrCP) ubiquitinates p-GLI1" +xref: Reactome:R-HSA-5610745 "SCF(beta-TrCP) ubiquitinates p-GLI2" +xref: Reactome:R-HSA-5610746 "SCF(beta-TrCP) ubiquitinates p-GLI3" +xref: Reactome:R-HSA-5652009 "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA" +xref: Reactome:R-HSA-5655170 "RCHY1 monoubiquitinates POLH" +xref: Reactome:R-HSA-5660753 "SIAH1:UBE2L6:Ubiquitin ubiquitinates SNCA" +xref: Reactome:R-HSA-5667107 "SIAH1, SIAH2 ubiquitinate SNCAIP" +xref: Reactome:R-HSA-5667111 "PARK2 K63-Ubiquitinates SNCAIP" +xref: Reactome:R-HSA-5668454 "K63polyUb-cIAP1,2 ubiquitinates TRAF3" +xref: Reactome:R-HSA-5668534 "cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK" +xref: Reactome:R-HSA-5675470 "BIRC2/3 (cIAP1/2) is autoubiquitinated" +xref: Reactome:R-HSA-5684250 "SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2" +xref: Reactome:R-HSA-5691108 "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2" +xref: Reactome:R-HSA-5693108 "TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains" +xref: Reactome:R-HSA-69598 "Ubiquitination of phosphorylated Cdc25A" +xref: Reactome:R-HSA-741386 "RIP2 induces K63-linked ubiquitination of NEMO" +xref: Reactome:R-HSA-75824 "Ubiquitination of Cyclin D1" +xref: Reactome:R-HSA-870449 "TRIM33 monoubiquitinates SMAD4" +xref: Reactome:R-HSA-8948709 "DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3" +xref: Reactome:R-HSA-8956106 "VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha" +xref: Reactome:R-HSA-9013069 "Ubiquitination of DLL/JAG ligands upon binding to NOTCH3" +xref: Reactome:R-HSA-9013974 "Auto-ubiquitination of TRAF3 within activated TLR3 complex" +xref: Reactome:R-HSA-9014342 "K63-linked ubiquitination of RIP1 bound to the activated TLR complex" +xref: Reactome:R-HSA-918224 "DDX58 is K63 polyubiquitinated" +xref: Reactome:R-HSA-936412 "RNF125 mediated ubiquitination of DDX58, IFIH1 and MADS" +xref: Reactome:R-HSA-936942 "Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2" +xref: Reactome:R-HSA-936986 "Activated TRAF6 synthesizes unanchored polyubiquitin chains" +xref: Reactome:R-HSA-9628444 "Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation" +xref: Reactome:R-HSA-975118 "TRAF6 ubiquitinqtes IRF7 in a K63-dependent manner following TLR7/8 or 9 stimulation" +xref: Reactome:R-HSA-975147 "Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane" +xref: Reactome:R-HSA-983140 "Transfer of Ub from E2 to substrate and release of E2" +xref: Reactome:R-HSA-983153 "E1 mediated ubiquitin activation" +xref: Reactome:R-HSA-983156 "Polyubiquitination of substrate" +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +relationship: part_of GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0004843 +name: thiol-dependent ubiquitin-specific protease activity +namespace: molecular_function +def: "Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein." [GOC:jh2, ISBN:0120793709] +synonym: "deubiquitinase" EXACT [GOC:vw, PMID:19261746] +synonym: "deubiquitinase activity" NARROW [GOC:bf] +synonym: "deubiquitinating enzyme" NARROW [PMID:19188440] +synonym: "deubiquitylase" EXACT [GOC:vw, PMID:15657442] +synonym: "ubiquitin C-terminal hydrolase activity" EXACT [EC:3.4.19.12] +synonym: "ubiquitin hydrolase activity" BROAD [GOC:rl] +synonym: "ubiquitin-specific protease activity" BROAD [] +synonym: "UBP" NARROW [] +synonym: "UCH2" NARROW [] +xref: Reactome:R-HSA-1358795 "Deubiquitination of RNF41 by P-USP8" +xref: Reactome:R-HSA-2179291 "UCHL5, USP15 deubiquitinate TGFBR1" +xref: Reactome:R-HSA-3215295 "USP7 deubiquitinates MDM2" +xref: Reactome:R-HSA-3215310 "USP7 deubiquitinates TP53 and counteracts MDM2" +xref: Reactome:R-HSA-4641236 "USP8 deubiquitinates FZD to potentiate WNT signaling" +xref: Reactome:R-HSA-5653770 "USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA" +xref: Reactome:R-HSA-5655466 "USP1:WDR48 deubiquitinates monoUb:K164-PCNA" +xref: Reactome:R-HSA-5696465 "USP45 deubiquitinates ERCC1" +xref: Reactome:R-HSA-6782069 "UVSSA:USP7 deubiquitinates ERCC6" +xref: Reactome:R-HSA-6786171 "FANCD2 deubiquitination by USP1:WDR48" +xref: Reactome:R-HSA-6807118 "USP7 deubiquitinates monoubiquitinated PTEN" +xref: Reactome:R-HSA-6807206 "USP13 and OTUD3 deubiquitinate PTEN" +xref: Reactome:R-HSA-8853503 "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin" +xref: Reactome:R-HSA-8853514 "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin" +xref: Reactome:R-HSA-8853515 "OTULIN,USP5 cleaves UBC yielding ubiquitin" +xref: Reactome:R-HSA-8853529 "OTULIN,USP5 cleaves UBB yielding ubiquitin" +xref: Reactome:R-HSA-8875443 "USP8 deubiquitinates LRIG1" +xref: Reactome:R-HSA-8986083 "USP33 deubiquitinates ROBO1" +is_a: GO:0036459 ! thiol-dependent ubiquitinyl hydrolase activity + +[Term] +id: GO:0004844 +name: uracil DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine." [GOC:elh, GOC:pr, PMID:9224623] +synonym: "uracil-DNA glycosylase activity" EXACT [] +xref: Reactome:R-HSA-110215 "Cleavage of uracil by UNG glycosylase" +xref: Reactome:R-HSA-110217 "Cleavage of 5-hydroxyluracil by UNG glycosylase" +is_a: GO:0097506 ! deaminated base DNA N-glycosylase activity + +[Term] +id: GO:0004845 +name: uracil phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil." [EC:2.4.2.9, RHEA:13017] +synonym: "UMP diphosphorylase activity" EXACT [EC:2.4.2.9] +synonym: "UMP pyrophosphorylase activity" EXACT [EC:2.4.2.9] +synonym: "UMP:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.9] +synonym: "UMP:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.9] +synonym: "UPRTase activity" EXACT [EC:2.4.2.9] +synonym: "uridine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.9] +synonym: "uridine monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.9] +synonym: "uridylate pyrophosphorylase activity" EXACT [EC:2.4.2.9] +synonym: "uridylic pyrophosphorylase activity" EXACT [EC:2.4.2.9] +xref: EC:2.4.2.9 +xref: KEGG_REACTION:R00966 +xref: MetaCyc:URACIL-PRIBOSYLTRANS-RXN +xref: RHEA:13017 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004846 +name: urate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide." [EC:1.7.3.3] +synonym: "urate:oxygen oxidoreductase activity" EXACT [EC:1.7.3.3] +synonym: "uric acid oxidase activity" EXACT [EC:1.7.3.3] +synonym: "uricase activity" EXACT [EC:1.7.3.3] +synonym: "uricase II activity" NARROW [EC:1.7.3.3] +xref: EC:1.7.3.3 +xref: MetaCyc:URATE-OXIDASE-RXN +xref: RHEA:21368 +xref: UM-BBD_reactionID:r1322 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor + +[Term] +id: GO:0004847 +name: urea carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate." [EC:6.3.4.6, RHEA:20896] +synonym: "ATP--urea amidolyase activity" EXACT [EC:6.3.4.6] +synonym: "UALase activity" EXACT [EC:6.3.4.6] +synonym: "UCA activity" EXACT [EC:6.3.4.6] +synonym: "urea amidolyase activity" EXACT [EC:6.3.4.6] +synonym: "urea carboxylase (hydrolysing)" EXACT [EC:6.3.4.6] +synonym: "urea carboxylase (hydrolyzing) activity" EXACT [EC:6.3.4.6] +synonym: "urea:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.3.4.6] +synonym: "urease (ATP-hydrolysing)" EXACT [EC:6.3.4.6] +synonym: "urease (ATP-hydrolyzing) activity" EXACT [EC:6.3.4.6] +xref: EC:6.3.4.6 +xref: KEGG_REACTION:R00774 +xref: MetaCyc:UREA-CARBOXYLASE-RXN +xref: RHEA:20896 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0004848 +name: ureidoglycolate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+)." [EC:3.5.1.116, RHEA:19809] +comment: Take care to annotate to the reaction, not simply the enzyme name. The name "ureidoglycolate hydrolase" has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19, GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3, GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name. +synonym: "(S)-ureidoglycolate amidohydrolase (decarboxylating)" EXACT [] +xref: EC:3.5.3.19 +xref: KEGG_REACTION:R00469 +xref: MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN +xref: RHEA:19809 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0004849 +name: uridine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + uridine = ADP + UMP." [EC:2.7.1.48] +synonym: "ATP:uridine 5'-phosphotransferase activity" EXACT [EC:2.7.1.48] +synonym: "pyrimidine ribonucleoside kinase activity" EXACT [EC:2.7.1.48] +synonym: "uridine kinase (phosphorylating)" EXACT [EC:2.7.1.48] +synonym: "uridine kinase reaction" EXACT [] +synonym: "uridine monophosphokinase activity" EXACT [EC:2.7.1.48] +synonym: "uridine phosphokinase activity" EXACT [EC:2.7.1.48] +synonym: "uridine-cytidine kinase activity" EXACT [EC:2.7.1.48] +xref: EC:2.7.1.48 +xref: MetaCyc:URIDINEKIN-RXN +xref: Reactome:R-HSA-8954327 "UCKL1 phosphorylates urindine, cytidine" +xref: RHEA:16825 +is_a: GO:0019206 ! nucleoside kinase activity +relationship: part_of GO:0006222 ! UMP biosynthetic process + +[Term] +id: GO:0004850 +name: uridine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate." [EC:2.4.2.3] +synonym: "pyrimidine phosphorylase activity" BROAD [EC:2.4.2.3] +synonym: "UPase activity" EXACT [EC:2.4.2.3] +synonym: "UPH" RELATED [EC:2.4.2.3] +synonym: "UrdPase activity" EXACT [EC:2.4.2.3] +synonym: "uridine:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.3] +xref: EC:2.4.2.3 +xref: MetaCyc:URPHOS-RXN +xref: Reactome:R-HSA-74372 "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]" +xref: Reactome:R-HSA-74376 "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)" +xref: RHEA:24388 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0004851 +name: uroporphyrin-III C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2." [EC:2.1.1.107] +synonym: "adenosylmethionine-uroporphyrinogen III methyltransferase activity" EXACT [EC:2.1.1.107] +synonym: "CobA" RELATED [EC:2.1.1.107] +synonym: "CysG" RELATED [EC:2.1.1.107] +synonym: "S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity" EXACT [EC:2.1.1.107] +synonym: "S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity" EXACT [EC:2.1.1.107] +synonym: "S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity" EXACT [EC:2.1.1.107] +synonym: "SirA" RELATED [EC:2.1.1.107] +synonym: "SUMT activity" EXACT [EC:2.1.1.107] +synonym: "urogen III methylase activity" EXACT [EC:2.1.1.107] +synonym: "uroporphyrinogen III methylase activity" EXACT [EC:2.1.1.107] +synonym: "uroporphyrinogen methyltransferase activity" EXACT [EC:2.1.1.107] +synonym: "uroporphyrinogen-III C-methyltransferase activity" EXACT [EC:2.1.1.107] +synonym: "uroporphyrinogen-III methylase activity" EXACT [EC:2.1.1.107] +synonym: "uroporphyrinogen-III methyltransferase activity" EXACT [EC:2.1.1.107] +xref: EC:2.1.1.107 +xref: MetaCyc:UROPORIIIMETHYLTRANSA-RXN +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0004852 +name: uroporphyrinogen-III synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III." [EC:4.2.1.75, RHEA:18965] +synonym: "hydroxymethylbilane hydro-lyase (cyclizing) activity" EXACT [EC:4.2.1.75] +synonym: "hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)" EXACT [EC:4.2.1.75] +synonym: "porphobilinogenase activity" EXACT [EC:4.2.1.75] +synonym: "URO-synthase activity" EXACT [EC:4.2.1.75] +synonym: "uroporphyrinogen III cosynthase activity" EXACT [EC:4.2.1.75] +synonym: "uroporphyrinogen isomerase activity" EXACT [EC:4.2.1.75] +synonym: "uroporphyrinogen-III cosynthase activity" EXACT [EC:4.2.1.75] +synonym: "uroporphyrinogen-III cosynthetase activity" EXACT [EC:4.2.1.75] +xref: EC:4.2.1.75 +xref: KEGG_REACTION:R03165 +xref: MetaCyc:UROGENIIISYN-RXN +xref: Reactome:R-HSA-189488 "UROS transforms HMB to URO3" +xref: RHEA:18965 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0004853 +name: uroporphyrinogen decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2." [EC:4.1.1.37] +synonym: "porphyrinogen carboxy-lyase activity" EXACT [EC:4.1.1.37] +synonym: "porphyrinogen decarboxylase activity" EXACT [EC:4.1.1.37] +synonym: "uroporphyrinogen III decarboxylase activity" EXACT [EC:4.1.1.37] +synonym: "uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)" EXACT [EC:4.1.1.37] +synonym: "uroporphyrinogen-III carboxy-lyase activity" EXACT [EC:4.1.1.37] +xref: EC:4.1.1.37 +xref: MetaCyc:UROGENDECARBOX-RXN +xref: Reactome:R-HSA-189425 "UROD decarboxylates URO3 to COPRO3" +xref: Reactome:R-HSA-190182 "UROD decarboxylates URO1 to COPRO1" +xref: RHEA:19865 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0004854 +name: xanthine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+." [EC:1.17.1.4] +synonym: "NAD-xanthine dehydrogenase activity" EXACT [EC:1.17.1.4] +synonym: "xanthine oxidoreductase activity" BROAD [EC:1.17.1.4] +synonym: "xanthine-NAD oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "xanthine/NAD(+) oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "xanthine/NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "xanthine:NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] +xref: EC:1.17.1.4 +xref: MetaCyc:RXN0-901 +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0004855 +name: xanthine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide." [EC:1.17.3.2] +synonym: "hypoxanthine-xanthine oxidase activity" BROAD [EC:1.17.3.2] +synonym: "schardinger enzyme" RELATED [EC:1.17.3.2] +synonym: "Schardinger enzyme activity" RELATED [EC:1.17.3.2] +synonym: "xanthine oxidoreductase activity" BROAD [EC:1.17.3.2] +synonym: "xanthine:O(2) oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "xanthine:O2 oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "xanthine:oxygen oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "xanthine:xanthine oxidase activity" EXACT [EC:1.17.3.2] +xref: EC:1.17.3.2 +xref: MetaCyc:XANTHINE-OXIDASE-RXN +xref: Reactome:R-HSA-74247 "Hypoxanthine + H2O + O2 => Xanthine + H2O2" +xref: Reactome:R-HSA-74258 "Xanthine + H2O + O2 => Urate + H2O2" +xref: RHEA:21132 +xref: UM-BBD_enzymeID:e0781 +is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor + +[Term] +id: GO:0004856 +name: xylulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+)." [EC:2.7.1.17, RHEA:10964] +synonym: "ATP:D-xylulose 5-phosphotransferase activity" EXACT [EC:2.7.1.17] +synonym: "D-xylulokinase activity" EXACT [EC:2.7.1.17] +synonym: "xylulokinase (phosphorylating)" EXACT [EC:2.7.1.17] +synonym: "xylulose kinase activity" EXACT [EC:2.7.1.17] +xref: EC:2.7.1.17 +xref: KEGG_REACTION:R01639 +xref: MetaCyc:XYLULOKIN-RXN +xref: Reactome:R-HSA-5662466 "XYLB phosphorylates D-xylulose" +xref: RHEA:10964 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0004857 +name: enzyme inhibitor activity +namespace: molecular_function +alt_id: GO:0048551 +def: "Binds to and stops, prevents or reduces the activity of an enzyme." [GOC:ai, GOC:ebc] +synonym: "metalloenzyme inhibitor activity" NARROW [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0043086 ! negative regulation of catalytic activity + +[Term] +id: GO:0004858 +name: dUTP pyrophosphatase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of dUTP pyrophosphatase." [GOC:mah] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004170 ! dUTP diphosphatase activity + +[Term] +id: GO:0004859 +name: phospholipase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid." [GOC:ai, GOC:rl] +is_a: GO:0055102 ! lipase inhibitor activity +relationship: negatively_regulates GO:0004620 ! phospholipase activity + +[Term] +id: GO:0004860 +name: protein kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] +is_a: GO:0019210 ! kinase inhibitor activity +is_a: GO:0019887 ! protein kinase regulator activity +relationship: negatively_regulates GO:0004672 ! protein kinase activity +relationship: part_of GO:0006469 ! negative regulation of protein kinase activity + +[Term] +id: GO:0004861 +name: cyclin-dependent protein serine/threonine kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase." [GOC:mah, GOC:pr] +synonym: "CDK inhibitor" RELATED [] +synonym: "cyclin dependent kinase inhibitor" RELATED [] +synonym: "cyclin dependent protein kinase inhibitor activity" EXACT [] +synonym: "cyclin-dependent kinase inhibitor" RELATED [] +synonym: "cyclin-dependent protein kinase inhibitor activity" BROAD [] +xref: Reactome:R-HSA-69562 "Inactivation of Cyclin E:Cdk2 complexes by p27/p21" +is_a: GO:0016538 ! cyclin-dependent protein serine/threonine kinase regulator activity +is_a: GO:0030291 ! protein serine/threonine kinase inhibitor activity +relationship: part_of GO:0045736 ! negative regulation of cyclin-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0004862 +name: cAMP-dependent protein kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a cAMP-dependent protein kinase." [GOC:mah] +xref: Reactome:R-HSA-180073 "DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function" +is_a: GO:0008603 ! cAMP-dependent protein kinase regulator activity +is_a: GO:0030291 ! protein serine/threonine kinase inhibitor activity +relationship: part_of GO:2000480 ! negative regulation of cAMP-dependent protein kinase activity + +[Term] +id: GO:0004864 +name: protein phosphatase inhibitor activity +namespace: molecular_function +alt_id: GO:1990681 +def: "Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins." [GOC:ai] +synonym: "phosphoprotein phosphatase inhibitor activity" EXACT [] +synonym: "protein phosphatase 2 inhibitor activity" NARROW [GOC:dph] +synonym: "protein phosphatase type 2A inhibitor activity" NARROW [] +is_a: GO:0019212 ! phosphatase inhibitor activity +is_a: GO:0019888 ! protein phosphatase regulator activity +relationship: negatively_regulates GO:0004721 ! phosphoprotein phosphatase activity +relationship: part_of GO:0032515 ! negative regulation of phosphoprotein phosphatase activity +created_by: rb +creation_date: 2015-03-03T23:57:25Z + +[Term] +id: GO:0004865 +name: protein serine/threonine phosphatase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate." [GOC:dph, GOC:tb] +is_a: GO:0004864 ! protein phosphatase inhibitor activity + +[Term] +id: GO:0004866 +name: endopeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides." [GOC:jl] +synonym: "alpha-2 macroglobulin" RELATED [] +synonym: "endoproteinase inhibitor" NARROW [] +synonym: "proteinase inhibitor" NARROW [] +is_a: GO:0030414 ! peptidase inhibitor activity +is_a: GO:0061135 ! endopeptidase regulator activity +relationship: negatively_regulates GO:0004175 ! endopeptidase activity +relationship: part_of GO:0010951 ! negative regulation of endopeptidase activity + +[Term] +id: GO:0004867 +name: serine-type endopeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme." [GOC:ai] +synonym: "serine protease inhibitor activity" NARROW [] +synonym: "serine proteinase inhibitor activity" NARROW [] +synonym: "serpin activity" NARROW [] +xref: Reactome:R-HSA-158795 "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1" +xref: Reactome:R-HSA-158800 "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1" +xref: Reactome:R-HSA-158893 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin" +xref: Reactome:R-HSA-159001 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR" +xref: Reactome:R-HSA-159005 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR" +is_a: GO:0004866 ! endopeptidase inhibitor activity +relationship: negatively_regulates GO:0004252 ! serine-type endopeptidase activity + +[Term] +id: GO:0004868 +name: obsolete serpin +namespace: molecular_function +def: "OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin." [GOC:ai, ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "serpin" EXACT [] +is_obsolete: true +consider: GO:0004867 + +[Term] +id: GO:0004869 +name: cysteine-type endopeptidase inhibitor activity +namespace: molecular_function +alt_id: GO:0004870 +def: "Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:dph, GOC:tb] +synonym: "cystatin" NARROW [GOC:jl] +synonym: "cysteine protease inhibitor activity" NARROW [GOC:dph, GOC:tb] +synonym: "thiol protease inhibitor" NARROW [] +is_a: GO:0004866 ! endopeptidase inhibitor activity +relationship: negatively_regulates GO:0008234 ! cysteine-type peptidase activity + +[Term] +id: GO:0004871 +name: obsolete signal transducer activity +namespace: molecular_function +alt_id: GO:0005062 +alt_id: GO:0009369 +alt_id: GO:0009370 +def: "OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:go_curators] +comment: This term was obsoleted because it was not clearly defined and is not a useful grouping term. +synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity" NARROW [] +synonym: "quorum sensing response regulator activity" NARROW [] +synonym: "quorum sensing signal generator activity" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0004873 +name: asialoglycoprotein receptor activity +namespace: molecular_function +def: "Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane." [GOC:bf, PMID:11278827, PMID:7624395, Wikipedia:Asialoglycoprotein] +subset: goslim_chembl +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0004874 +name: obsolete aryl hydrocarbon receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding." [GOC:ai, PMID:1325649, PMID:7493958, Wikipedia:Aryl_hydrocarbon_receptor] +comment: This term was obsoleted because it represents a gene product. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16732 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0004875 +name: complement receptor activity +namespace: molecular_function +alt_id: GO:0004942 +def: "Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:ai, GOC:pg, GOC:signaling, ISBN:0781735149, PMID:11884446] +comment: Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways. +synonym: "anaphylatoxin receptor activity" RELATED [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0001848 ! complement binding +relationship: part_of GO:0002430 ! complement receptor mediated signaling pathway + +[Term] +id: GO:0004876 +name: complement component C3a receptor activity +namespace: molecular_function +alt_id: GO:0004943 +def: "Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:mah, GOC:pg, GOC:signaling, ISBN:0781735149] +synonym: "C3a anaphylatoxin receptor activity" RELATED [] +is_a: GO:0004875 ! complement receptor activity + +[Term] +id: GO:0004877 +name: complement component C3b receptor activity +namespace: molecular_function +def: "Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0001847 ! opsonin receptor activity +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001850 ! complement component C3a binding +relationship: has_part GO:0001851 ! complement component C3b binding + +[Term] +id: GO:0004878 +name: complement component C5a receptor activity +namespace: molecular_function +alt_id: GO:0004944 +def: "Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:mah, GOC:pg, GOC:signaling, ISBN:0781735149] +synonym: "C5a anaphylatoxin receptor activity" RELATED [] +is_a: GO:0001847 ! opsonin receptor activity +is_a: GO:0004875 ! complement receptor activity +relationship: has_part GO:0001856 ! complement component C5a binding +relationship: part_of GO:0038178 ! complement component C5a signaling pathway + +[Term] +id: GO:0004879 +name: nuclear receptor activity +namespace: molecular_function +alt_id: GO:0003708 +alt_id: GO:0004880 +alt_id: GO:0004882 +alt_id: GO:0004884 +alt_id: GO:0004886 +alt_id: GO:0004887 +alt_id: GO:0008434 +alt_id: GO:0038050 +alt_id: GO:0038051 +alt_id: GO:0038052 +def: "Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II." [GOC:signaling, GOC:txnOH] +comment: GO:0004879 is intended for annotation of nuclear receptors that regulate transcription by binding directly to DNA. When the nuclear receptor functions by binding to other transcription factors or transcription factor complexes, consider instead annotating to 'nuclear receptor transcription coactivator activity ; GO:0030374'. +synonym: "1,25-(OH)2D3 receptor activity" NARROW [Wikipedia:Calcitriol] +synonym: "9-cis retinoic acid receptor activity" NARROW [] +synonym: "androgen receptor activity" NARROW [] +synonym: "calcitriol receptor activity" NARROW [] +synonym: "ecdysteroid hormone receptor activity" NARROW [] +synonym: "estrogen nuclear receptor activity" NARROW [GOC:bf] +synonym: "glucocorticoid receptor activity" NARROW [GOC:bf] +synonym: "juvenile hormone receptor activity" NARROW [] +synonym: "ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity" EXACT [] +synonym: "ligand-dependent nuclear receptor activity" RELATED [GOC:bf] +synonym: "ligand-dependent transcription factor activity" RELATED [GOC:bf] +synonym: "nuclear hormone receptor" NARROW [] +synonym: "nuclear receptor activity" RELATED [GOC:bf] +synonym: "retinoic acid receptor activity" NARROW [] +synonym: "retinoid-X receptor activity" NARROW [GOC:bf] +synonym: "RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding" NARROW [] +synonym: "RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding" EXACT [] +synonym: "RXR" NARROW [] +synonym: "thyroid hormone receptor activity" NARROW [] +synonym: "vitamin A receptor activity" NARROW [] +synonym: "vitamin D receptor activity" NARROW [] +synonym: "vitamin D3 receptor activity" NARROW [GOC:bf, Wikipedia:Calcitriol_receptor] +is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific +is_a: GO:0098531 ! ligand-activated transcription factor activity +relationship: part_of GO:0030522 ! intracellular receptor signaling pathway + +[Term] +id: GO:0004883 +name: glucocorticoid receptor activity +namespace: molecular_function +def: "Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function." [GOC:signaling, PMID:17689856, PMID:20920967] +comment: If the mechanism by which a glucocorticoid receptor functions is known, consider instead annotating to the child terms 'glucocorticoid-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038050' or 'glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038051'. +is_a: GO:0003707 ! steroid hormone receptor activity +relationship: part_of GO:0042921 ! glucocorticoid receptor signaling pathway +relationship: part_of GO:0043402 ! glucocorticoid mediated signaling pathway + +[Term] +id: GO:0004888 +name: transmembrane signaling receptor activity +namespace: molecular_function +alt_id: GO:0004926 +alt_id: GO:0099600 +def: "Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction." [GOC:go_curators, Wikipedia:Transmembrane_receptor] +comment: This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores. +synonym: "transmembrane receptor activity" BROAD [GOC:bf, GOC:signaling] +synonym: "transmembrane signalling receptor activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-193672 "Sphingomyelinase is activated by the NGF:p75NTR complex" +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0004890 +name: GABA-A receptor activity +namespace: molecular_function +def: "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels." [PMID:8974333] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'. +synonym: "ionotropic GABA receptor activity" EXACT [GOC:bf] +is_a: GO:0016917 ! GABA receptor activity + +[Term] +id: GO:0004892 +name: obsolete B cell receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes the receptor type, and not an activity. +synonym: "B cell receptor activity" EXACT [] +is_obsolete: true +consider: GO:0003823 + +[Term] +id: GO:0004894 +name: obsolete T cell receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes a receptor type, and not an activity. +synonym: "T cell receptor activity" EXACT [] +is_obsolete: true +consider: GO:0032394 +consider: GO:0032395 +consider: GO:0042605 + +[Term] +id: GO:0004895 +name: cell adhesion receptor activity +namespace: molecular_function +def: "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins." [GOC:BHF-UCL, Wikipedia:Cell_adhesion] +comment: Reinstated term from obsolete. +is_a: GO:0038023 ! signaling receptor activity +is_a: GO:0098631 ! cell adhesion mediator activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15237 xsd:anyURI + +[Term] +id: GO:0004896 +name: cytokine receptor activity +namespace: molecular_function +alt_id: GO:0004907 +def: "Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:mah] +synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor activity" RELATED [] +synonym: "IL receptor" NARROW [] +synonym: "interleukin receptor activity" NARROW [http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0019955 ! cytokine binding +relationship: part_of GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0004897 +name: ciliary neurotrophic factor receptor activity +namespace: molecular_function +def: "Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +synonym: "CNTF receptor activity" EXACT [GOC:mah] +synonym: "gp130" RELATED [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0070119 ! ciliary neurotrophic factor binding +relationship: part_of GO:0070120 ! ciliary neurotrophic factor-mediated signaling pathway + +[Term] +id: GO:0004898 +name: obsolete gp130 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a gene product. +synonym: "gp130" EXACT [] +is_obsolete: true +consider: GO:0004897 +consider: GO:0004915 +consider: GO:0004921 + +[Term] +id: GO:0004900 +name: erythropoietin receptor activity +namespace: molecular_function +def: "Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0038162 ! erythropoietin-mediated signaling pathway + +[Term] +id: GO:0004901 +name: granulocyte macrophage colony-stimulating factor receptor activity +namespace: molecular_function +alt_id: GO:0030525 +def: "Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +synonym: "CSF-2 receptor activity" EXACT [GOC:bf] +synonym: "CSF2R" RELATED [GOC:bf] +synonym: "GM-CSF receptor activity" EXACT [] +synonym: "GMC-SF receptor activity" EXACT [] +synonym: "granulocyte macrophage colony stimulating factor receptor activity" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042021 ! granulocyte macrophage colony-stimulating factor complex binding +relationship: part_of GO:0038157 ! granulocyte-macrophage colony-stimulating factor signaling pathway + +[Term] +id: GO:0004902 +name: granulocyte colony-stimulating factor receptor activity +namespace: molecular_function +alt_id: GO:0030524 +def: "Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +synonym: "CSF3R" RELATED [GOC:bf] +synonym: "G-CSF receptor activity" EXACT [GOC:bf] +synonym: "granulocyte colony stimulating factor receptor activity" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0051916 ! granulocyte colony-stimulating factor binding +relationship: part_of GO:0038158 ! granulocyte colony-stimulating factor signaling pathway + +[Term] +id: GO:0004903 +name: growth hormone receptor activity +namespace: molecular_function +def: "Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling] +is_a: GO:0004896 ! cytokine receptor activity + +[Term] +id: GO:0004904 +name: interferon receptor activity +namespace: molecular_function +def: "Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling, PMID:9607096] +synonym: "IFN receptor activity" EXACT [GOC:mah] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019961 ! interferon binding + +[Term] +id: GO:0004905 +name: type I interferon receptor activity +namespace: molecular_function +def: "Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:signaling, ISBN:0126896631, PMID:15546383, PMID:16681834, PR:000025848] +synonym: "interferon-alpha receptor activity" NARROW [] +synonym: "interferon-alpha/beta receptor activity" NARROW [] +synonym: "interferon-beta receptor activity" NARROW [] +synonym: "interferon-delta receptor activity" NARROW [] +synonym: "interferon-epsilon receptor activity" NARROW [] +synonym: "interferon-kappa receptor activity" NARROW [] +synonym: "interferon-omega receptor activity" NARROW [] +synonym: "interferon-tau receptor activity" NARROW [] +synonym: "interferon-zeta receptor activity" NARROW [] +synonym: "type I IFN receptor activity" EXACT [GOC:mah] +is_a: GO:0004904 ! interferon receptor activity +relationship: has_part GO:0019962 ! type I interferon binding +relationship: part_of GO:0060337 ! type I interferon signaling pathway + +[Term] +id: GO:0004906 +name: interferon-gamma receptor activity +namespace: molecular_function +def: "Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:ai, GOC:signaling, ISBN:0126896631, PMID:15546383] +synonym: "IFN-gamma receptor activity" EXACT [GOC:mah] +synonym: "IFNG receptor activity" EXACT [GOC:mah] +synonym: "type II interferon receptor activity" BROAD [] +is_a: GO:0004904 ! interferon receptor activity +relationship: has_part GO:0019964 ! interferon-gamma binding +relationship: part_of GO:0060333 ! interferon-gamma-mediated signaling pathway + +[Term] +id: GO:0004908 +name: interleukin-1 receptor activity +namespace: molecular_function +def: "Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response." [GOC:jl] +synonym: "IL-1 receptor activity" EXACT [] +synonym: "IL-1R" EXACT [] +xref: Wikipedia:Interleukin-1_receptor +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019966 ! interleukin-1 binding + +[Term] +id: GO:0004909 +name: interleukin-1, type I, activating receptor activity +namespace: molecular_function +alt_id: GO:0019967 +def: "Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins." [PMID:15062641, PMID:18613828] +synonym: "IL-1 type I, activating binding" EXACT [] +synonym: "IL-1 type I, activating receptor" EXACT [] +synonym: "interleukin-1 activating receptor activity" EXACT [GOC:mah] +synonym: "interleukin-1 type I receptor activity" EXACT [GOC:mah] +synonym: "interleukin-1, type I, activating binding" RELATED [] +is_a: GO:0004908 ! interleukin-1 receptor activity +relationship: part_of GO:0070498 ! interleukin-1-mediated signaling pathway + +[Term] +id: GO:0004910 +name: interleukin-1, type II, blocking receptor activity +namespace: molecular_function +alt_id: GO:0019968 +def: "Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors." [PMID:15062641, PMID:18613828] +synonym: "IL-1 type II, blocking binding" EXACT [] +synonym: "IL-1 type II, blocking receptor" EXACT [] +synonym: "interleukin-1 blocking receptor activity" EXACT [GOC:mah] +synonym: "interleukin-1 type II receptor activity" EXACT [GOC:mah] +synonym: "interleukin-1, type II, blocking binding" RELATED [] +is_a: GO:0004908 ! interleukin-1 receptor activity + +[Term] +id: GO:0004911 +name: interleukin-2 receptor activity +namespace: molecular_function +def: "Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-2 receptor activity" EXACT [GOC:mah] +synonym: "IL-2R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019976 ! interleukin-2 binding +relationship: part_of GO:0038110 ! interleukin-2-mediated signaling pathway + +[Term] +id: GO:0004912 +name: interleukin-3 receptor activity +namespace: molecular_function +def: "Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-3 receptor activity" EXACT [GOC:mah] +synonym: "IL-3R" EXACT [] +xref: Wikipedia:Interleukin-3_receptor +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019978 ! interleukin-3 binding +relationship: part_of GO:0036016 ! cellular response to interleukin-3 +relationship: part_of GO:0038156 ! interleukin-3-mediated signaling pathway + +[Term] +id: GO:0004913 +name: interleukin-4 receptor activity +namespace: molecular_function +def: "Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-4 receptor activity" EXACT [GOC:mah] +synonym: "IL-4R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019979 ! interleukin-4 binding +relationship: part_of GO:0035771 ! interleukin-4-mediated signaling pathway + +[Term] +id: GO:0004914 +name: interleukin-5 receptor activity +namespace: molecular_function +def: "Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-5 receptor activity" EXACT [GOC:mah] +synonym: "IL-5R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019980 ! interleukin-5 binding +relationship: part_of GO:0038043 ! interleukin-5-mediated signaling pathway + +[Term] +id: GO:0004915 +name: interleukin-6 receptor activity +namespace: molecular_function +def: "Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "gp130" RELATED [] +synonym: "IL-6 receptor activity" EXACT [GOC:mah] +synonym: "IL-6R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019981 ! interleukin-6 binding +relationship: part_of GO:0070102 ! interleukin-6-mediated signaling pathway + +[Term] +id: GO:0004917 +name: interleukin-7 receptor activity +namespace: molecular_function +def: "Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-7 receptor activity" EXACT [GOC:mah] +synonym: "IL-7R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019982 ! interleukin-7 binding +relationship: part_of GO:0038111 ! interleukin-7-mediated signaling pathway + +[Term] +id: GO:0004918 +name: interleukin-8 receptor activity +namespace: molecular_function +def: "Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-8 receptor activity" EXACT [GOC:mah] +synonym: "IL-8R" EXACT [] +is_a: GO:0016494 ! C-X-C chemokine receptor activity +relationship: has_part GO:0019959 ! interleukin-8 binding +relationship: part_of GO:0038112 ! interleukin-8-mediated signaling pathway + +[Term] +id: GO:0004919 +name: interleukin-9 receptor activity +namespace: molecular_function +def: "Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-9 receptor activity" EXACT [GOC:mah] +synonym: "IL-9R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019983 ! interleukin-9 binding +relationship: part_of GO:0038113 ! interleukin-9-mediated signaling pathway + +[Term] +id: GO:0004920 +name: interleukin-10 receptor activity +namespace: molecular_function +def: "Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-10 receptor activity" EXACT [GOC:mah] +synonym: "IL-10R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019969 ! interleukin-10 binding + +[Term] +id: GO:0004921 +name: interleukin-11 receptor activity +namespace: molecular_function +def: "Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "gp130" RELATED [] +synonym: "IL-11 receptor activity" EXACT [GOC:mah] +synonym: "IL-11R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019970 ! interleukin-11 binding +relationship: part_of GO:0038154 ! interleukin-11-mediated signaling pathway + +[Term] +id: GO:0004923 +name: leukemia inhibitory factor receptor activity +namespace: molecular_function +alt_id: GO:0004899 +def: "Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:mah, GOC:signaling] +synonym: "leukemia inhibitory factor receptor beta-protein activity" NARROW [GOC:mah] +synonym: "LIF receptor activity" EXACT [GOC:mah] +is_a: GO:0004897 ! ciliary neurotrophic factor receptor activity +relationship: part_of GO:0048861 ! leukemia inhibitory factor signaling pathway + +[Term] +id: GO:0004924 +name: oncostatin-M receptor activity +namespace: molecular_function +def: "Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0038165 ! oncostatin-M-mediated signaling pathway + +[Term] +id: GO:0004925 +name: prolactin receptor activity +namespace: molecular_function +def: "Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0038161 ! prolactin signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0004927 +name: obsolete sevenless receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a gene product rather than an activity. +synonym: "sevenless receptor activity" EXACT [] +is_obsolete: true +consider: GO:0004714 +consider: GO:0004888 +consider: GO:0008288 + +[Term] +id: GO:0004928 +name: obsolete frizzled receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity." [GOC:go_curators] +comment: This term was made obsolete because it represents a gene product rather than an activity. +synonym: "frizzled receptor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0042813 +consider: GO:0016055 + +[Term] +id: GO:0004929 +name: obsolete frizzled-2 receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity." [GOC:go_curators] +comment: This term was made obsolete because it represents a gene product rather than an activity. +synonym: "frizzled-2 receptor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0042813 +consider: GO:0007223 + +[Term] +id: GO:0004930 +name: G protein-coupled receptor activity +namespace: molecular_function +alt_id: GO:0001622 +alt_id: GO:0001623 +alt_id: GO:0001624 +alt_id: GO:0001625 +alt_id: GO:0016526 +def: "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR] +subset: goslim_chembl +synonym: "EBV-induced receptor" NARROW [] +synonym: "Epstein-Barr Virus-induced receptor activity" NARROW [] +synonym: "G protein coupled receptor activity" EXACT [] +synonym: "G protein linked receptor activity" EXACT [] +synonym: "G-protein coupled receptor activity" EXACT [] +synonym: "G-protein coupled receptor activity, unknown ligand" NARROW [] +synonym: "G-protein linked receptor activity" EXACT [] +synonym: "GPCR activity" EXACT [] +synonym: "ligand-dependent GPCR activity" EXACT [] +synonym: "Mas proto-oncogene receptor activity" NARROW [] +synonym: "orphan G protein coupled receptor activity" NARROW [] +synonym: "orphan G-protein coupled receptor activity" NARROW [] +synonym: "orphan GPCR activity" NARROW [] +synonym: "RDC1 receptor activity" NARROW [] +synonym: "receptor activity, G-protein coupled" EXACT [GOC:bf] +synonym: "SREB receptor" NARROW [] +synonym: "super conserved receptor expressed in brain receptor activity" NARROW [] +xref: Reactome:R-HSA-114552 "G12/13 activation by PAR" +xref: Reactome:R-HSA-114558 "Gq activation by PAR" +xref: Reactome:R-HSA-167408 "The high affinity receptor complex binds to G-protein" +xref: Wikipedia:GPCR +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0004931 +name: extracellularly ATP-gated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane." [GOC:bf, GOC:mah, PMID:9755289] +comment: Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'. +synonym: "P2X receptor" RELATED [PMID:9755289] +synonym: "purinoceptor" BROAD [] +synonym: "purinoreceptor" BROAD [] +xref: Reactome:R-HSA-877187 "P2X7 mediates loss of intracellular K+" +is_a: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity +is_a: GO:0035381 ! ATP-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0004932 +name: mating-type factor pheromone receptor activity +namespace: molecular_function +def: "Combining with a mating-type factor pheromone to initiate a change in cell activity." [GOC:dph, GOC:vw] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +is_a: GO:0016503 ! pheromone receptor activity + +[Term] +id: GO:0004933 +name: mating-type a-factor pheromone receptor activity +namespace: molecular_function +def: "Combining with the mating-type a-factor pheromone to initiate a change in cell activity." [GOC:mah] +synonym: "class D G protein coupled receptor activity" BROAD [] +synonym: "class D G-protein coupled receptor activity" BROAD [] +synonym: "class D G-protein-coupled receptor activity" BROAD [] +synonym: "class D GPCR activity" BROAD [] +is_a: GO:0004932 ! mating-type factor pheromone receptor activity +is_a: GO:0036318 ! peptide pheromone receptor activity + +[Term] +id: GO:0004934 +name: mating-type alpha-factor pheromone receptor activity +namespace: molecular_function +def: "Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity." [GOC:mah] +synonym: "class D G protein coupled receptor activity" BROAD [] +synonym: "class D G-protein coupled receptor activity" BROAD [] +synonym: "class D G-protein-coupled receptor activity" BROAD [] +synonym: "class D GPCR activity" BROAD [] +is_a: GO:0004932 ! mating-type factor pheromone receptor activity +is_a: GO:0036318 ! peptide pheromone receptor activity + +[Term] +id: GO:0004935 +name: adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex." [GOC:bf, GOC:mah, IUPHAR_GPCR:1274] +synonym: "adrenoceptor activity" EXACT [] +xref: Wikipedia:Adrenergic_receptor +is_a: GO:0008227 ! G protein-coupled amine receptor activity +relationship: part_of GO:0071875 ! adrenergic receptor signaling pathway + +[Term] +id: GO:0004936 +name: alpha-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors." [GOC:mah, IUPHAR_GPCR:1274] +synonym: "alpha adrenoceptor" EXACT [] +is_a: GO:0004935 ! adrenergic receptor activity + +[Term] +id: GO:0004937 +name: alpha1-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein." [GOC:cb, GOC:mah, IUPHAR_GPCR:1274] +synonym: "alpha1 adrenoceptor" EXACT [] +is_a: GO:0004936 ! alpha-adrenergic receptor activity + +[Term] +id: GO:0004938 +name: alpha2-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein." [GOC:cb, GOC:mah, IUPHAR_GPCR:1274] +synonym: "alpha2 adrenoceptor" EXACT [] +is_a: GO:0004936 ! alpha-adrenergic receptor activity + +[Term] +id: GO:0004939 +name: beta-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein." [GOC:cb, GOC:mah, IUPHAR_GPCR:1274] +synonym: "beta adrenoceptor" EXACT [] +is_a: GO:0004935 ! adrenergic receptor activity + +[Term] +id: GO:0004940 +name: beta1-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors." [GOC:mah, IUPHAR_GPCR:1274] +synonym: "beta1 adrenoceptor" EXACT [] +is_a: GO:0004939 ! beta-adrenergic receptor activity + +[Term] +id: GO:0004941 +name: beta2-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors." [GOC:mah, IUPHAR_GPCR:1274] +synonym: "beta2 adrenoceptor" EXACT [] +is_a: GO:0004939 ! beta-adrenergic receptor activity + +[Term] +id: GO:0004945 +name: angiotensin type II receptor activity +namespace: molecular_function +def: "An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms." [GOC:mah, PMID:10977869] +is_a: GO:0001595 ! angiotensin receptor activity + +[Term] +id: GO:0004946 +name: bombesin receptor activity +namespace: molecular_function +def: "Combining with bombesin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: part_of GO:0031989 ! bombesin receptor signaling pathway + +[Term] +id: GO:0004947 +name: bradykinin receptor activity +namespace: molecular_function +def: "Combining with bradykinin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0004948 +name: calcitonin receptor activity +namespace: molecular_function +def: "Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:21649645] +is_a: GO:0097642 ! calcitonin family receptor activity +relationship: has_part GO:0032841 ! calcitonin binding + +[Term] +id: GO:0004949 +name: cannabinoid receptor activity +namespace: molecular_function +def: "Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids." [GOC:dph, IUPHAR_GPCR:1279, Wikipedia:Cannabinoid] +synonym: "cannaboid receptor" EXACT [] +synonym: "endocannabinoid receptor activity" NARROW [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: part_of GO:0038171 ! cannabinoid signaling pathway + +[Term] +id: GO:0004950 +name: chemokine receptor activity +namespace: molecular_function +def: "Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, GOC:signaling, IUPHAR_GPCR:1280, PMID:12183377, PMID:8662823, Wikipedia:Chemokine] +is_a: GO:0001637 ! G protein-coupled chemoattractant receptor activity +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019956 ! chemokine binding +relationship: part_of GO:0070098 ! chemokine-mediated signaling pathway + +[Term] +id: GO:0004951 +name: cholecystokinin receptor activity +namespace: molecular_function +def: "Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone." [GOC:signaling, PMID:9835394] +synonym: "CCK receptor activity" EXACT [PR:000005110, Wikipedia:Cholecystokinin] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0038188 ! cholecystokinin signaling pathway + +[Term] +id: GO:0004952 +name: dopamine neurotransmitter receptor activity +namespace: molecular_function +def: "Combining with the neurotransmitter dopamine to initiate a change in cell activity." [GOC:PARL, IUPHAR_GPCR:1282, PMID:21711983] +is_a: GO:0098960 ! postsynaptic neurotransmitter receptor activity +relationship: has_part GO:0035240 ! dopamine binding +relationship: part_of GO:0001963 ! synaptic transmission, dopaminergic +relationship: part_of GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0004953 +name: icosanoid receptor activity +namespace: molecular_function +def: "Combining with an icosanoid to initiate a change in cell activity." [GOC:dph] +synonym: "eicosanoid receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: has_part GO:0050542 ! icosanoid binding + +[Term] +id: GO:0004954 +name: prostanoid receptor activity +namespace: molecular_function +def: "Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity." [ISBN:0198506732] +is_a: GO:0004953 ! icosanoid receptor activity + +[Term] +id: GO:0004955 +name: prostaglandin receptor activity +namespace: molecular_function +def: "Combining with a prostaglandin (PG) to initiate a change in cell activity." [ISBN:0198506732] +is_a: GO:0004954 ! prostanoid receptor activity + +[Term] +id: GO:0004956 +name: prostaglandin D receptor activity +namespace: molecular_function +def: "Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity." [ISBN:0198506732] +synonym: "PGD receptor activity" RELATED [] +synonym: "PGD(2) receptor activity" EXACT [] +is_a: GO:0004955 ! prostaglandin receptor activity + +[Term] +id: GO:0004957 +name: prostaglandin E receptor activity +namespace: molecular_function +def: "Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity." [ISBN:0198506732] +synonym: "PGE receptor activity" RELATED [] +synonym: "PGE(2) receptor activity" EXACT [] +is_a: GO:0004955 ! prostaglandin receptor activity + +[Term] +id: GO:0004958 +name: prostaglandin F receptor activity +namespace: molecular_function +def: "Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity." [ISBN:0198506732] +synonym: "PGF receptor activity" RELATED [] +synonym: "PGF(2-alpha) receptor activity" EXACT [] +is_a: GO:0004955 ! prostaglandin receptor activity + +[Term] +id: GO:0004960 +name: thromboxane receptor activity +namespace: molecular_function +def: "Combining with a thromboxane (TXA) to initiate a change in cell activity." [ISBN:0198506732] +synonym: "TXA receptor activity" EXACT [] +is_a: GO:0004954 ! prostanoid receptor activity + +[Term] +id: GO:0004961 +name: thromboxane A2 receptor activity +namespace: molecular_function +def: "Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein." [GOC:signaling, ISBN:0198506732] +synonym: "TXA(2) receptor activity" EXACT [] +synonym: "TXA2 receptor activity" EXACT [PMID:15242977] +is_a: GO:0004960 ! thromboxane receptor activity +relationship: part_of GO:0038193 ! thromboxane A2 signaling pathway + +[Term] +id: GO:0004962 +name: endothelin receptor activity +namespace: molecular_function +alt_id: GO:0001599 +alt_id: GO:0001600 +def: "Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph, GOC:signaling, IUPHAR_GPCR:1283, IUPHAR_RECEPTOR:2263, IUPHAR_RECEPTOR:2265] +synonym: "endothelin-A receptor activity" NARROW [GOC:bf, PMID:8582288] +synonym: "endothelin-B receptor activity" NARROW [GOC:bf, PMID:8582288] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0086100 ! endothelin receptor signaling pathway + +[Term] +id: GO:0004963 +name: follicle-stimulating hormone receptor activity +namespace: molecular_function +def: "Combining with follicle-stimulating hormone to initiate a change in cell activity." [GOC:mah] +synonym: "follicle stimulating hormone receptor activity" EXACT [] +synonym: "FSH receptor activity" EXACT [] +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: part_of GO:0042699 ! follicle-stimulating hormone signaling pathway + +[Term] +id: GO:0004964 +name: luteinizing hormone receptor activity +namespace: molecular_function +alt_id: GO:0004976 +def: "Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity." [ISBN:0198506732, PMID:18848524, PMID:1922095] +synonym: "LH receptor" EXACT [PMID:18848524] +synonym: "LHR" EXACT [PMID:18848524] +synonym: "lutropin receptor" EXACT [ISBN:0198506732] +synonym: "lutropin-choriogonadotropic hormone receptor" RELATED [PMID:1922095] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: part_of GO:0042700 ! luteinizing hormone signaling pathway + +[Term] +id: GO:0004965 +name: G protein-coupled GABA receptor activity +namespace: molecular_function +def: "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:ai, GOC:bf, IUPHAR_RECEPTOR:1276, Wikipedia:GABAB_receptor] +synonym: "G-protein coupled GABA receptor activity" EXACT [] +synonym: "GABA-B receptor activity" RELATED [GOC:bf] +synonym: "metabotropic GABA receptor" RELATED [Wikipedia:GABAB_receptor] +xref: Reactome:R-HSA-1013012 "Binding of Gbeta/gamma to GIRK/Kir3 channels" +xref: Reactome:R-HSA-1013013 "Association of GABA B receptor with G protein beta-gamma subunits" +is_a: GO:0016917 ! GABA receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity + +[Term] +id: GO:0004966 +name: galanin receptor activity +namespace: molecular_function +def: "Combining with galanin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0004967 +name: glucagon receptor activity +namespace: molecular_function +def: "Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, GOC:signaling, PMID:22438981] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0071377 ! cellular response to glucagon stimulus + +[Term] +id: GO:0004968 +name: gonadotropin-releasing hormone receptor activity +namespace: molecular_function +def: "Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus." [GOC:mah] +synonym: "GnRH receptor activity" EXACT [] +synonym: "gonadotrophin-releasing hormone receptor activity" EXACT [GOC:dph] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: has_part GO:0051448 ! gonadotropin-releasing hormone binding +relationship: part_of GO:0097211 ! cellular response to gonadotropin-releasing hormone + +[Term] +id: GO:0004969 +name: histamine receptor activity +namespace: molecular_function +def: "Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] +is_a: GO:0008227 ! G protein-coupled amine receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +relationship: has_part GO:0051381 ! histamine binding + +[Term] +id: GO:0004970 +name: ionotropic glutamate receptor activity +namespace: molecular_function +def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts." [ISBN:0198506732] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'. +is_a: GO:0008066 ! glutamate receptor activity +is_a: GO:0022824 ! transmitter-gated ion channel activity +relationship: part_of GO:0035235 ! ionotropic glutamate receptor signaling pathway + +[Term] +id: GO:0004971 +name: AMPA glutamate receptor activity +namespace: molecular_function +def: "An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium." [GOC:mah, PMID:10049997, PMID:8804111] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. +synonym: "alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity" EXACT [] +synonym: "AMPA receptor activity" EXACT [] +is_a: GO:0004970 ! ionotropic glutamate receptor activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0004972 +name: NMDA glutamate receptor activity +namespace: molecular_function +def: "An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages." [GOC:mah, PMID:10049997] +comment: The name of this receptor comes from its selective activation by N-methyl-D-aspartate (NMDA). Note that this term represents an activity and not a gene product. +synonym: "N-methyl-D-aspartate selective glutamate receptor activity" EXACT [] +synonym: "NMDA receptor" EXACT [] +xref: Wikipedia:NMDA_receptor +is_a: GO:0004970 ! ionotropic glutamate receptor activity +is_a: GO:0022843 ! voltage-gated cation channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0004973 +name: obsolete N-methyl-D-aspartate receptor-associated protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "N-methyl-D-aspartate receptor-associated protein activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 + +[Term] +id: GO:0004974 +name: leukotriene receptor activity +namespace: molecular_function +def: "Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine." [GOC:ai, ISBN:0198506732] +is_a: GO:0004953 ! icosanoid receptor activity +relationship: part_of GO:0061737 ! leukotriene signaling pathway + +[Term] +id: GO:0004977 +name: melanocortin receptor activity +namespace: molecular_function +def: "Combining with melanocortin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0004978 +name: corticotropin receptor activity +namespace: molecular_function +def: "Combining with corticotropin to initiate a change in cell activity." [GOC:ai] +synonym: "ACTH receptor activity" EXACT [] +synonym: "adrenocorticotropic hormone receptor activity" EXACT [] +synonym: "adrenocorticotropin receptor activity" EXACT [] +is_a: GO:0004977 ! melanocortin receptor activity +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: has_part GO:0042562 ! hormone binding + +[Term] +id: GO:0004979 +name: beta-endorphin receptor activity +namespace: molecular_function +def: "Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC)." [GOC:ai, GOC:bf, Wikipedia:Beta-endorphin] +synonym: "mu-opioid receptor activity" RELATED [GOC:bf] +is_a: GO:0004977 ! melanocortin receptor activity +is_a: GO:0004985 ! opioid receptor activity +is_a: GO:0008188 ! neuropeptide receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +relationship: has_part GO:0031626 ! beta-endorphin binding + +[Term] +id: GO:0004980 +name: melanocyte-stimulating hormone receptor activity +namespace: molecular_function +def: "Combining with melanocyte-stimulating hormone to initiate a change in cell activity." [GOC:jl, PMID:7581459] +synonym: "melanocyte stimulating hormone receptor activity" EXACT [] +synonym: "melanophore-stimulating hormone receptor activity" EXACT [] +synonym: "MSH receptor activity" BROAD [] +synonym: "MSHR activity" BROAD [] +is_a: GO:0004977 ! melanocortin receptor activity +relationship: has_part GO:0042562 ! hormone binding + +[Term] +id: GO:0004982 +name: N-formyl peptide receptor activity +namespace: molecular_function +def: "Combining with an N-formyl peptide to initiate a change in cell activity." [GOC:ai] +synonym: "Fmet-leu-phe receptor" EXACT [] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0004983 +name: neuropeptide Y receptor activity +namespace: molecular_function +def: "Combining with neuropeptide Y to initiate a change in cell activity." [PMID:9315606] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0004984 +name: olfactory receptor activity +namespace: molecular_function +def: "Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell." [GOC:bf, GOC:dph, GOC:sart, PMID:19135896, PMID:21041441] +synonym: "odorant receptor activity" EXACT [PMID:19135896, PMID:21041441] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell + +[Term] +id: GO:0004985 +name: opioid receptor activity +namespace: molecular_function +def: "Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein." [GOC:ai, GOC:bf, PMID:20494127] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0038003 ! opioid receptor signaling pathway + +[Term] +id: GO:0004986 +name: obsolete delta-opioid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands." [IUPHAR_RECEPTOR:317, PMID:10471416] +comment: This term was made obsolete because the receptor is defined based on its pharmacological properties. +synonym: "delta-opioid receptor activity" EXACT [] +xref: Wikipedia:Delta_Opioid_receptor +is_obsolete: true +consider: GO:0038046 + +[Term] +id: GO:0004987 +name: obsolete kappa-opioid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins." [IUPHAR_RECEPTOR:318] +comment: This term was made obsolete because the receptor is defined based on its pharmacological properties. +synonym: "kappa-opioid receptor activity" EXACT [] +xref: Wikipedia:Kappa_Opioid_receptor +is_obsolete: true +consider: GO:0038048 + +[Term] +id: GO:0004988 +name: obsolete mu-opioid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins." [IUPHAR_RECEPTOR:319] +comment: This term was made obsolete because the receptor is defined based on its pharmacological properties. +synonym: "mu-opioid receptor activity" EXACT [] +xref: Wikipedia:Mu_Opioid_receptor +is_obsolete: true +consider: GO:0004979 +consider: GO:0038046 +consider: GO:0038047 + +[Term] +id: GO:0004989 +name: octopamine receptor activity +namespace: molecular_function +def: "Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist." [GOC:ai] +is_a: GO:0008227 ! G protein-coupled amine receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity + +[Term] +id: GO:0004990 +name: oxytocin receptor activity +namespace: molecular_function +def: "Combining with oxytocin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0004991 +name: parathyroid hormone receptor activity +namespace: molecular_function +def: "Combining with parathyroid hormone to initiate a change in cell activity." [GOC:mah] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0004992 +name: platelet activating factor receptor activity +namespace: molecular_function +def: "Combining with platelet activating factor to initiate a change in cell activity." [GOC:mah] +synonym: "PAF receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0004993 +name: G protein-coupled serotonin receptor activity +namespace: molecular_function +alt_id: GO:0001585 +alt_id: GO:0016609 +def: "Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates." [GOC:ai] +synonym: "5-HT receptor" EXACT [] +synonym: "5-hydroxytryptamine receptor" EXACT [] +synonym: "G protein coupled serotonin receptor activity" EXACT [] +synonym: "G-protein coupled serotonin receptor activity" EXACT [] +xref: Wikipedia:5-HT_receptor +is_a: GO:0008227 ! G protein-coupled amine receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +is_a: GO:0099589 ! serotonin receptor activity +relationship: has_part GO:0051378 ! serotonin binding +relationship: part_of GO:0098664 ! G protein-coupled serotonin receptor signaling pathway + +[Term] +id: GO:0004994 +name: somatostatin receptor activity +namespace: molecular_function +def: "Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28)." [GOC:ai, GOC:bf, Wikipedia:Somatostatin] +synonym: "GHIH receptor activity" EXACT [Wikipedia:Somatostatin] +synonym: "growth hormone-inhibiting hormone receptor activity" EXACT [Wikipedia:Somatostatin] +synonym: "somatotrophin release inhibiting factor receptor activity" EXACT [Wikipedia:Somatostatin] +synonym: "SRIF receptor activity" EXACT [Wikipedia:Somatostatin] +synonym: "SST receptor activity" EXACT [Wikipedia:Somatostatin] +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: part_of GO:0038170 ! somatostatin signaling pathway + +[Term] +id: GO:0004995 +name: tachykinin receptor activity +namespace: molecular_function +def: "Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein." [GOC:ai, GOC:bf, PMID:7639617, Wikipedia:Tachykinin] +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: part_of GO:0007217 ! tachykinin receptor signaling pathway + +[Term] +id: GO:0004996 +name: thyroid-stimulating hormone receptor activity +namespace: molecular_function +def: "Combining with thyroid-stimulating hormone to initiate a change in cell activity." [GOC:mah] +synonym: "thyroid stimulating hormone receptor activity" EXACT [] +synonym: "thyrotropin receptor" EXACT [] +synonym: "TSH receptor activity" EXACT [] +xref: Wikipedia:Thyrotropin_receptor +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: part_of GO:0038194 ! thyroid-stimulating hormone signaling pathway + +[Term] +id: GO:0004997 +name: thyrotropin-releasing hormone receptor activity +namespace: molecular_function +def: "Combining with thyrotropin-releasing hormone to initiate a change in cell activity." [GOC:mah] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0004998 +name: transferrin receptor activity +namespace: molecular_function +def: "Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates." [GOC:bf, PMID:2678449, PMID:3011819] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0004999 +name: vasoactive intestinal polypeptide receptor activity +namespace: molecular_function +def: "Combining with vasoactive intestinal polypeptide to initiate a change in cell activity." [GOC:mah] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0005000 +name: vasopressin receptor activity +namespace: molecular_function +alt_id: GO:0016931 +def: "Combining with vasopressin to initiate a change in cell activity." [GOC:ai] +synonym: "vasopressin activated calcium mobilizing receptor activity" NARROW [] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0005001 +name: transmembrane receptor protein tyrosine phosphatase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48] +is_a: GO:0004725 ! protein tyrosine phosphatase activity +is_a: GO:0019198 ! transmembrane receptor protein phosphatase activity + +[Term] +id: GO:0005003 +name: ephrin receptor activity +namespace: molecular_function +def: "Combining with an ephrin to initiate a change in cell activity." [GOC:mah, PMID:9530499] +synonym: "Eph receptor activity" EXACT [] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: part_of GO:0048013 ! ephrin receptor signaling pathway + +[Term] +id: GO:0005004 +name: GPI-linked ephrin receptor activity +namespace: molecular_function +def: "Combining with a GPI-anchored ephrin to initiate a change in cell activity." [GOC:mah, PMID:9530499] +synonym: "GPI-linked Eph receptor activity" EXACT [] +is_a: GO:0005003 ! ephrin receptor activity + +[Term] +id: GO:0005005 +name: transmembrane-ephrin receptor activity +namespace: molecular_function +def: "Combining with a transmembrane ephrin to initiate a change in cell activity." [GOC:mah, PMID:9530499] +synonym: "transmembrane-Eph receptor activity" EXACT [] +is_a: GO:0005003 ! ephrin receptor activity + +[Term] +id: GO:0005006 +name: epidermal growth factor-activated receptor activity +namespace: molecular_function +alt_id: GO:0005023 +def: "Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "EGF receptor activity" EXACT [] +synonym: "EGFR" EXACT [] +synonym: "epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "TGF-alpha receptor activity" EXACT [] +synonym: "transforming growth factor-alpha receptor activity" EXACT [] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0048408 ! epidermal growth factor binding +relationship: part_of GO:0007173 ! epidermal growth factor receptor signaling pathway + +[Term] +id: GO:0005007 +name: fibroblast growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:mah] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "FGF receptor activity" EXACT [] +synonym: "FGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "FGFR" EXACT [] +synonym: "fibroblast growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0017134 ! fibroblast growth factor binding +relationship: part_of GO:0008543 ! fibroblast growth factor receptor signaling pathway + +[Term] +id: GO:0005008 +name: hepatocyte growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:mah] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "hepatocyte growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "HGF receptor activity" EXACT [] +synonym: "HGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0036458 ! hepatocyte growth factor binding +relationship: part_of GO:0048012 ! hepatocyte growth factor receptor signaling pathway + +[Term] +id: GO:0005009 +name: insulin-activated receptor activity +namespace: molecular_function +def: "Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity." [ISBN:0198506732] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "insulin receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: has_part GO:0043559 ! insulin binding +relationship: part_of GO:0008286 ! insulin receptor signaling pathway + +[Term] +id: GO:0005010 +name: insulin-like growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:mah] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "IGF receptor activity" EXACT [] +synonym: "IGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "insulin-like growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0005520 ! insulin-like growth factor binding +relationship: part_of GO:0048009 ! insulin-like growth factor receptor signaling pathway + +[Term] +id: GO:0005011 +name: macrophage colony-stimulating factor receptor activity +namespace: molecular_function +def: "Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [GOC:mah, GOC:signaling] +synonym: "CSF-1" NARROW [] +synonym: "Fms" NARROW [] +synonym: "M-CSF receptor activity" EXACT [GOC:bf] +synonym: "macrophage colony stimulating factor receptor activity" EXACT [] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: part_of GO:0038145 ! macrophage colony-stimulating factor signaling pathway + +[Term] +id: GO:0005012 +name: obsolete Neu/ErbB-2 receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a class of receptor rather than an activity. +synonym: "Neu/ErbB-2 receptor activity" EXACT [] +is_obsolete: true +consider: GO:0043125 + +[Term] +id: GO:0005013 +name: obsolete neurotrophin TRK receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jid] +comment: This term was made obsolete because it represents a gene product. +synonym: "neurotrophin TRK receptor activity" EXACT [] +is_obsolete: true +consider: GO:0004714 +consider: GO:0007165 +consider: GO:0019838 +consider: GO:0043121 + +[Term] +id: GO:0005014 +name: obsolete neurotrophin TRKA receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jid] +comment: This term was made obsolete because it represents a gene product. +synonym: "neurotrophin TRKA receptor activity" EXACT [] +is_obsolete: true +consider: GO:0004714 +consider: GO:0007165 +consider: GO:0043121 +consider: GO:0048406 + +[Term] +id: GO:0005015 +name: obsolete neurotrophin TRKB receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jid] +comment: This term was made obsolete because it represents a gene product. +synonym: "neurotrophin TRKB receptor activity" EXACT [] +is_obsolete: true +consider: GO:0004714 +consider: GO:0007165 +consider: GO:0043121 +consider: GO:0048403 + +[Term] +id: GO:0005016 +name: obsolete neurotrophin TRKC receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jid] +comment: This term was made obsolete because it represents a gene product. +synonym: "neurotrophin TRKC receptor activity" EXACT [] +is_obsolete: true +consider: GO:0004714 +consider: GO:0007165 +consider: GO:0043121 + +[Term] +id: GO:0005017 +name: platelet-derived growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:mah] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "PDGF receptor activity" EXACT [] +synonym: "PDGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "PDGFR activity" EXACT [] +synonym: "platelet-derived growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0048407 ! platelet-derived growth factor binding +relationship: part_of GO:0036120 ! cellular response to platelet-derived growth factor stimulus +relationship: part_of GO:0048008 ! platelet-derived growth factor receptor signaling pathway + +[Term] +id: GO:0005018 +name: platelet-derived growth factor alpha-receptor activity +namespace: molecular_function +def: "Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity." [PMID:1657917] +synonym: "alphaPDGF receptor activity" EXACT [PMID:10372961] +synonym: "PDGF alpha-receptor activity" EXACT [] +is_a: GO:0005017 ! platelet-derived growth factor-activated receptor activity +relationship: part_of GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway + +[Term] +id: GO:0005019 +name: platelet-derived growth factor beta-receptor activity +namespace: molecular_function +def: "Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity." [PMID:1657917] +synonym: "betaPDGF receptor activity" RELATED [PMID:10372961] +synonym: "PDGF beta-receptor activity" EXACT [] +is_a: GO:0005017 ! platelet-derived growth factor-activated receptor activity +relationship: part_of GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway + +[Term] +id: GO:0005020 +name: stem cell factor receptor activity +namespace: molecular_function +def: "Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation." [GOC:jl, GOC:signaling, PMID:10698217] +synonym: "KIT" RELATED [PR:000009345] +synonym: "KIT ligand receptor activity" EXACT [PR:000009345] +synonym: "KL receptor activity" EXACT [PR:000009345] +synonym: "SCF receptor activity" EXACT [PR:000009345] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: part_of GO:0038109 ! Kit signaling pathway + +[Term] +id: GO:0005021 +name: vascular endothelial growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:mah, GOC:signaling] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "vascular endothelial growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "VEGF receptor activity" EXACT [] +synonym: "VEGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "VEGFR activity" EXACT [] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: has_part GO:0038085 ! vascular endothelial growth factor binding +relationship: part_of GO:0038084 ! vascular endothelial growth factor signaling pathway + +[Term] +id: GO:0005024 +name: transforming growth factor beta-activated receptor activity +namespace: molecular_function +def: "Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:mah, GOC:signaling] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "TGF-beta receptor activity" EXACT [] +synonym: "TGFbeta receptor activity" EXACT [] +synonym: "TGFbeta-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "TGFbetaR" EXACT [] +synonym: "transforming growth factor beta receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity + +[Term] +id: GO:0005025 +name: transforming growth factor beta receptor activity, type I +namespace: molecular_function +def: "Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals." [GOC:mah, Reactome:R-HSA-170846] +synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] +synonym: "type I TGF-beta receptor activity" EXACT [] +synonym: "type I TGFbeta receptor activity" EXACT [] +synonym: "type I transforming growth factor beta receptor activity" EXACT [] +is_a: GO:0005024 ! transforming growth factor beta-activated receptor activity + +[Term] +id: GO:0005026 +name: transforming growth factor beta receptor activity, type II +namespace: molecular_function +def: "Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor." [GOC:mah, Reactome:R-HSA-170861] +synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] +synonym: "type II TGF-beta receptor activity" EXACT [] +synonym: "type II TGFbeta receptor activity" EXACT [] +synonym: "type II transforming growth factor beta receptor activity" EXACT [] +xref: Reactome:R-HSA-170843 "TGFBR2 phosphorylates TGFBR1" +is_a: GO:0005024 ! transforming growth factor beta-activated receptor activity +relationship: has_part GO:0050431 ! transforming growth factor beta binding + +[Term] +id: GO:0005027 +name: obsolete NGF/TNF (6 C-domain) receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a protein family rather than a molecular function. +synonym: "NGF/TNF (6 C-domain) receptor activity" EXACT [] +is_obsolete: true +consider: GO:0005031 + +[Term] +id: GO:0005028 +name: obsolete CD40 receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes the receptor type, and not an activity. +synonym: "CD40 receptor activity" EXACT [] +is_obsolete: true +consider: GO:0042615 + +[Term] +id: GO:0005029 +name: obsolete CD27 receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes the receptor type, and not an activity. +synonym: "CD27 receptor activity" EXACT [] +is_obsolete: true +consider: GO:0042614 + +[Term] +id: GO:0005030 +name: neurotrophin receptor activity +namespace: molecular_function +def: "Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity." [GOC:jl, GOC:signaling, http://www.mercksource.com/] +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0043121 ! neurotrophin binding +relationship: part_of GO:0038179 ! neurotrophin signaling pathway + +[Term] +id: GO:0005031 +name: tumor necrosis factor-activated receptor activity +namespace: molecular_function +alt_id: GO:0005032 +alt_id: GO:0005033 +def: "Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function." [GOC:jl, http://lookwayup.com/] +synonym: "NGF/TNF (6 C-domain) receptor activity" NARROW [] +synonym: "TNF receptor activity" EXACT [] +synonym: "TNF receptor activity, type I" NARROW [] +synonym: "TNF receptor activity, type II" NARROW [] +synonym: "tumor necrosis factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "tumor necrosis factor receptor activity, type I" NARROW [] +synonym: "tumor necrosis factor receptor activity, type II" NARROW [] +is_a: GO:0005035 ! death receptor activity +relationship: has_part GO:0043120 ! tumor necrosis factor binding +relationship: part_of GO:0033209 ! tumor necrosis factor-mediated signaling pathway + +[Term] +id: GO:0005034 +name: osmosensor activity +namespace: molecular_function +def: "Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell." [GOC:dph, GOC:tb] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140299 ! small molecule sensor activity + +[Term] +id: GO:0005035 +name: death receptor activity +namespace: molecular_function +def: "Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death." [GOC:bf, GOC:BHF, GOC:ecd, GOC:mtg_apoptosis, GOC:rl, PMID:10209153] +synonym: "apoptosis-activating receptor activity" RELATED [GOC:bf] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0012501 ! programmed cell death + +[Term] +id: GO:0005037 +name: obsolete death receptor adaptor protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "death receptor adaptor protein activity" EXACT [] +is_obsolete: true +consider: GO:0005123 +consider: GO:0005515 + +[Term] +id: GO:0005038 +name: obsolete death receptor interacting protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "death receptor interacting protein activity" EXACT [] +is_obsolete: true +consider: GO:0005123 +consider: GO:0005515 + +[Term] +id: GO:0005039 +name: obsolete death receptor-associated factor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "death receptor-associated factor activity" EXACT [] +is_obsolete: true +consider: GO:0005123 +consider: GO:0005515 + +[Term] +id: GO:0005041 +name: low-density lipoprotein particle receptor activity +namespace: molecular_function +alt_id: GO:0008032 +def: "Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis." [GOC:bf, ISBN:0198506732] +synonym: "LDL receptor" EXACT [] +synonym: "LDLR activity" EXACT [GOC:bf] +synonym: "low-density lipoprotein receptor activity" RELATED [] +xref: Reactome:R-HSA-2404131 "LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol" +xref: Reactome:R-HSA-2424254 "LDLR transports extracellular CR:atREs to cytosol" +xref: Wikipedia:LDL_receptor +is_a: GO:0030228 ! lipoprotein particle receptor activity +relationship: has_part GO:0030169 ! low-density lipoprotein particle binding + +[Term] +id: GO:0005042 +name: netrin receptor activity +namespace: molecular_function +def: "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:dph, GOC:signaling, PMID:15960985] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0038007 ! netrin-activated signaling pathway + +[Term] +id: GO:0005043 +name: netrin receptor activity involved in chemorepulsion +namespace: molecular_function +def: "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin." [GOC:dph, GOC:signaling] +synonym: "netrin receptor activity involved in negative chemotaxis" EXACT [GOC:bf] +synonym: "repulsive netrin receptor activity" EXACT [GOC:bf] +is_a: GO:0005042 ! netrin receptor activity +intersection_of: GO:0005042 ! netrin receptor activity +intersection_of: part_of GO:0050919 ! negative chemotaxis +relationship: part_of GO:0050919 ! negative chemotaxis + +[Term] +id: GO:0005044 +name: scavenger receptor activity +namespace: molecular_function +def: "Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs)." [GOC:bf, PMID:11790542, PMID:12379907, PMID:12621157, PMID:20981357] +comment: Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0038187' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. For receptors that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children. +subset: goslim_chembl +synonym: "macrophage receptor activity" NARROW [] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0005045 +name: obsolete endoplasmic reticulum receptor activity +namespace: molecular_function +def: "OBSOLETE. A receptor in the endoplasmic reticulum." [GOC:ai] +comment: This term was made obsolete because it represents cellular component and molecular function information. +synonym: "endoplasmic reticulum receptor activity" EXACT [] +is_obsolete: true +consider: GO:0038024 + +[Term] +id: GO:0005046 +name: KDEL sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [GOC:ai] +synonym: "KDEL receptor activity" NARROW [] +is_a: GO:0046923 ! ER retention sequence binding + +[Term] +id: GO:0005047 +name: signal recognition particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the signal recognition particle." [ISBN:0198506732] +comment: See also the cellular component term 'signal recognition particle, endoplasmic reticulum targeting ; GO:0005786'. +synonym: "docking protein" BROAD [] +synonym: "signal recognition particle receptor" NARROW [] +is_a: GO:0043021 ! ribonucleoprotein complex binding + +[Term] +id: GO:0005048 +name: signal sequence binding +namespace: molecular_function +alt_id: GO:0008249 +def: "Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized." [GOC:ai] +synonym: "leader sequence binding" NARROW [] +synonym: "protein signal sequence binding" NARROW [] +synonym: "signal sequence receptor" NARROW [] +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0005049 +name: nuclear export signal receptor activity +namespace: molecular_function +alt_id: GO:0008262 +def: "Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein." [GOC:bf, GOC:mah, GOC:pg, GOC:vw, PMID:11743003, PMID:25802992, PMID:28713609, Wikipedia:Nuclear_transport] +synonym: "exportin activity" RELATED [] +synonym: "importin-alpha binding" RELATED [] +synonym: "importin-alpha export receptor activity" NARROW [GO:0008262] +synonym: "NES receptor" EXACT [] +is_a: GO:0140142 ! nucleocytoplasmic carrier activity +intersection_of: GO:0140142 ! nucleocytoplasmic carrier activity +intersection_of: part_of GO:0051168 ! nuclear export +relationship: part_of GO:0051168 ! nuclear export +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14336 xsd:anyURI + +[Term] +id: GO:0005050 +name: obsolete peroxisome receptor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes a cellular component. +synonym: "peroxisome receptor" EXACT [] +is_obsolete: true +consider: GO:0005777 +consider: GO:0038023 + +[Term] +id: GO:0005052 +name: peroxisome matrix targeting signal-1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L." [GOC:mah, PMID:11687502] +synonym: "peroxisomal targeting signal 1 (PTS1) binding" EXACT [PMID:14709540] +synonym: "peroxisome targeting signal-1 binding" EXACT [] +synonym: "peroxisome targeting signal-1 receptor" NARROW [] +synonym: "PEX5" NARROW [] +synonym: "PTS1 binding" EXACT [PMID:14709540] +synonym: "PTS1 receptor" NARROW [] +is_a: GO:0000268 ! peroxisome targeting sequence binding + +[Term] +id: GO:0005053 +name: peroxisome matrix targeting signal-2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F)." [GOC:mah, PMID:11687502] +synonym: "peroxisomal targeting signal 2 (PTS2) binding" EXACT [PMID:14709540] +synonym: "peroxisome targeting signal-2 binding" EXACT [] +synonym: "peroxisome targeting signal-2 receptor" NARROW [] +synonym: "PEX7" NARROW [] +synonym: "PTS2 binding" EXACT [PMID:14709540] +synonym: "PTS2 receptor" EXACT [] +is_a: GO:0000268 ! peroxisome targeting sequence binding + +[Term] +id: GO:0005054 +name: obsolete peroxisome integral membrane receptor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes a cellular component. +synonym: "Pas20p" RELATED [] +synonym: "peroxisome integral membrane receptor" EXACT [] +is_obsolete: true +consider: GO:0038023 + +[Term] +id: GO:0005055 +name: laminin receptor activity +namespace: molecular_function +def: "Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity." [GOC:ai, PMID:2970671] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'. +is_a: GO:0098631 ! cell adhesion mediator activity +relationship: has_part GO:0043236 ! laminin binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0005056 +name: tiggrin receptor activity +namespace: molecular_function +def: "Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling, PMID:9521906] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0005057 +name: obsolete signal transducer activity, downstream of receptor +namespace: molecular_function +def: "OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell." [GOC:bf] +comment: This term was obsoleted because it was not clearly defined. +synonym: "intracellular signal transducer activity" EXACT [GOC:bf] +synonym: "receptor signaling protein activity" EXACT [] +synonym: "receptor signalling protein activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0005061 +name: obsolete aryl hydrocarbon receptor nuclear translocator activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "aryl hydrocarbon receptor nuclear translocator activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005065 +name: obsolete heterotrimeric G-protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a cellular component and not a molecular function. +synonym: "heterotrimeric G-protein" EXACT [] +is_obsolete: true +replaced_by: GO:0005834 + +[Term] +id: GO:0005066 +name: obsolete transmembrane receptor protein tyrosine kinase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "transmembrane receptor protein tyrosine kinase signaling protein activity" EXACT [] +synonym: "transmembrane receptor protein tyrosine kinase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0007169 +consider: GO:0035556 + +[Term] +id: GO:0005068 +name: transmembrane receptor protein tyrosine kinase adaptor activity +namespace: molecular_function +alt_id: GO:0005069 +def: "The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07, PMID:10502414, PMID:20565848] +synonym: "transmembrane receptor protein tyrosine kinase adaptor protein activity" EXACT [] +synonym: "transmembrane receptor protein tyrosine kinase docking protein activity" RELATED [] +is_a: GO:0030159 ! signaling receptor complex adaptor activity +is_a: GO:0030971 ! receptor tyrosine kinase binding +relationship: part_of GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0005070 +name: obsolete SH3/SH2 adaptor activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68)." [GOC:mah, GOC:so] +comment: This term was obsoleted because molecular adaptors should be represented by the type of molecules they serve to adapt, and not by their domains. +synonym: "SH3/SH2 adaptor protein activity" NARROW [] +is_obsolete: true + +[Term] +id: GO:0005071 +name: obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "transmembrane receptor protein serine/threonine kinase signaling protein activity" EXACT [] +synonym: "transmembrane receptor protein serine/threonine kinase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0007178 +consider: GO:0035556 + +[Term] +id: GO:0005072 +name: obsolete transforming growth factor beta receptor, cytoplasmic mediator activity +namespace: molecular_function +def: "OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus." [GOC:hjd] +comment: This term was obsoleted because it is redundant with other terms. +synonym: "TGF-beta receptor, cytoplasmic mediator activity" EXACT [] +synonym: "TGFbeta receptor, cytoplasmic mediator activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16202 xsd:anyURI +is_obsolete: true +consider: GO:0000981 + +[Term] +id: GO:0005073 +name: obsolete common-partner SMAD protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it names a family of gene products. +synonym: "common-partner SMAD protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005074 +name: obsolete inhibitory SMAD protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it names a family of gene products. +synonym: "inhibitory SMAD protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005075 +name: obsolete pathway-specific SMAD protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a family of gene products. +synonym: "pathway-specific SMAD protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005076 +name: obsolete receptor signaling protein serine/threonine kinase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "receptor signaling protein serine/threonine kinase signaling protein activity" EXACT [] +synonym: "receptor signalling protein serine/threonine kinase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0035556 + +[Term] +id: GO:0005077 +name: obsolete MAP-kinase anchoring activity +namespace: molecular_function +def: "OBSOLETE. Binds to MAP kinase and anchors it to a particular subcellular location." [GOC:ai] +comment: This term was made obsolete because it represents a combination of process and function information. +synonym: "MAP-kinase anchor protein activity" EXACT [] +synonym: "MAP-kinase anchoring activity" EXACT [] +is_obsolete: true +consider: GO:0008104 +consider: GO:0051019 + +[Term] +id: GO:0005078 +name: MAP-kinase scaffold activity +namespace: molecular_function +def: "The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently." [PMID:12511654, PMID:15213240, PMID:9405336] +synonym: "MAP-kinase scaffold protein activity" EXACT [] +is_a: GO:0019900 ! kinase binding +is_a: GO:0035591 ! signaling adaptor activity +relationship: part_of GO:0043410 ! positive regulation of MAPK cascade + +[Term] +id: GO:0005079 +name: obsolete protein kinase A anchoring activity +namespace: molecular_function +def: "OBSOLETE. Binds to protein kinase A and anchors it to a particular subcellular location." [PMID:10354567] +comment: This term was made obsolete because it represents a combination of process and function information. +synonym: "A-kinase anchor protein activity" EXACT [] +synonym: "AKAP activity" EXACT [] +synonym: "protein kinase A anchoring activity" EXACT [] +is_obsolete: true +consider: GO:0008104 +consider: GO:0051018 + +[Term] +id: GO:0005080 +name: protein kinase C binding +namespace: molecular_function +alt_id: GO:0072568 +alt_id: GO:0072569 +alt_id: GO:0097024 +def: "Interacting selectively and non-covalently with protein kinase C." [GOC:jl] +synonym: "PKC alpha binding" EXACT [] +synonym: "PKC binding" EXACT [] +synonym: "PKC delta binding" EXACT [GOC:BHF, GOC:pr] +synonym: "PKC eta binding" EXACT [GOC:BHF, GOC:pr] +synonym: "protein kinase C alpha binding" NARROW [] +synonym: "protein kinase C delta binding" NARROW [] +synonym: "protein kinase C eta binding" NARROW [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0005081 +name: obsolete receptor signaling protein serine/threonine phosphatase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "receptor signaling protein serine/threonine phosphatase signaling protein activity" EXACT [] +synonym: "receptor signalling protein serine/threonine phosphatase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0035556 + +[Term] +id: GO:0005082 +name: obsolete receptor signaling protein tyrosine phosphatase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "receptor signaling protein tyrosine phosphatase signaling protein activity" EXACT [] +synonym: "receptor signalling protein tyrosine phosphatase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0035556 + +[Term] +id: GO:0005085 +name: guanyl-nucleotide exchange factor activity +namespace: molecular_function +alt_id: GO:0008433 +alt_id: GO:0016219 +alt_id: GO:0019839 +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:kd, GOC:mah] +comment: Note that guanyl-nucleotide exchange factor (GEF) activity alters binding affinity, but not GTPase catalytic activity directly. Therefore GO:0005085 is under 'regulation of GTPase activity' but is not a 'GTPase regulator', which is reserved for cases where the action of one gene product directly alters the rate of catalysis by another gene product. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_yeast +synonym: "GDP-dissociation stimulator activity" EXACT [] +synonym: "GDS" EXACT [] +synonym: "GEF" EXACT [] +synonym: "GNRP" NARROW [] +synonym: "guanyl-nucleotide release factor activity" EXACT [] +synonym: "guanyl-nucleotide releasing factor" EXACT [] +xref: Reactome:R-HSA-114544 "p115-RhoGEF activation of RHOA" +xref: Reactome:R-HSA-1168636 "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP" +xref: Reactome:R-HSA-1433415 "Activation of RAC1" +xref: Reactome:R-HSA-156913 "Regeneration of eEF1A:GTP by eEF1B activity" +xref: Reactome:R-HSA-169904 "C3G stimulates nucleotide exchange on Rap1" +xref: Reactome:R-HSA-170979 "(Frs2)C3G stimulates nucleotide exchange on Rap1" +xref: Reactome:R-HSA-187746 "RIT/RIN are activated" +xref: Reactome:R-HSA-2029445 "Activation of CDC42 by unknown mechanism" +xref: Reactome:R-HSA-2029451 "Activation of RAC1 by VAV" +xref: Reactome:R-HSA-2029467 "Activation of RAC1 by CRKII:DOCK180:ELMO" +xref: Reactome:R-HSA-203977 "SAR1 Activation And Membrane Binding" +xref: Reactome:R-HSA-205039 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor" +xref: Reactome:R-HSA-2424476 "Activation of RAC1 by VAV2/3" +xref: Reactome:R-HSA-2485180 "MII catalyses GDP/GTP exchange on Gt" +xref: Reactome:R-HSA-2730840 "Activation of RAC1 by VAV" +xref: Reactome:R-HSA-354173 "Activation of Rap1 by cytosolic GEFs" +xref: Reactome:R-HSA-379044 "Liganded Gs-activating GPCR acts as a GEF for Gs" +xref: Reactome:R-HSA-379048 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11" +xref: Reactome:R-HSA-380073 "Liganded Gi-activating GPCR acts as a GEF for Gi" +xref: Reactome:R-HSA-389348 "Activation of Rac1 by pVav1" +xref: Reactome:R-HSA-389350 "Activation of Cdc42 by pVav1" +xref: Reactome:R-HSA-392195 "Gi activation by P2Y purinoceptor 12" +xref: Reactome:R-HSA-3928592 "p190RhoGEF exchanges GTP for GDP on RHOA, activating it" +xref: Reactome:R-HSA-3928612 "KALRN exchanges GTP for GDP on RAC1, activating it" +xref: Reactome:R-HSA-3928628 "VAV exchanges GTP for GDP on RAC1, activating it" +xref: Reactome:R-HSA-3928632 "ITSN1 exchanges GTP for GDP on CDC42, activating it" +xref: Reactome:R-HSA-3928633 "bPIX exchanges GTP for GDP on RAC, activating it" +xref: Reactome:R-HSA-3928642 "TIAM1 exchanges GTP for GDP on RAC1, activating it" +xref: Reactome:R-HSA-3928651 "NGEF exchanges GTP for GDP on RHOA" +xref: Reactome:R-HSA-392870 "Gs activation by prostacyclin receptor" +xref: Reactome:R-HSA-3965444 "WNT:FZD complex promotes G-protein nucleotide exchange" +xref: Reactome:R-HSA-399995 "Muscarinic Acetylcholine Receptor M3 activates Gq" +xref: Reactome:R-HSA-4093336 "p-TIAM1 exchanges GTP for GDP on RAC1, activating it" +xref: Reactome:R-HSA-416530 "GPR40:fatty acid activates Gq" +xref: Reactome:R-HSA-418579 "Gq activation by P2Y purinoceptor 1" +xref: Reactome:R-HSA-420883 "Opsins act as GEFs for G alpha-t" +xref: Reactome:R-HSA-428750 "Gq activation by TP receptor" +xref: Reactome:R-HSA-428917 "G13 activation by TP receptor" +xref: Reactome:R-HSA-442273 "VAV1 is a GEF for Rho/Rac family GTPases" +xref: Reactome:R-HSA-442291 "VAV2 is a GEF for Rho/Rac family kinases" +xref: Reactome:R-HSA-442314 "VAV3 is a GEF for Rho/Rac family kinases" +xref: Reactome:R-HSA-445064 "Activation of Rac1 by VAV2" +xref: Reactome:R-HSA-5218829 "VEGF induces CDC42 activation by unknown mechanism" +xref: Reactome:R-HSA-5218839 "DOCK180:ELMO exchanges GTP for GDP, activating RAC1" +xref: Reactome:R-HSA-5218850 "VAV exchanges GTP for GDP on RAC1, activating it" +xref: Reactome:R-HSA-5694409 "Nucleotide exchange on RAB1" +xref: Reactome:R-HSA-6807868 "GBF1 stimulates ARF nucleotide exchange" +xref: Reactome:R-HSA-6811429 "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange" +xref: Reactome:R-HSA-749453 "Liganded Gz-activating GPCR acts as a GEF for Gz" +xref: Reactome:R-HSA-751029 "Liganded G12/13-activating GPCR acts as a GEF for G12/13" +xref: Reactome:R-HSA-825631 "Glucagon:GCGR mediates GTP-GDP exchange" +xref: Reactome:R-HSA-8848618 "Activation of RAC1 by the PXN:CRK complex" +xref: Reactome:R-HSA-8850041 "RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18" +xref: Reactome:R-HSA-8851827 "RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1" +xref: Reactome:R-HSA-8851877 "RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET" +xref: Reactome:R-HSA-8851899 "RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET" +xref: Reactome:R-HSA-8875568 "RAPGEF1 activates RAP1" +xref: Reactome:R-HSA-8875591 "DOCK7 activates RAC1" +xref: Reactome:R-HSA-8964604 "CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated" +xref: Reactome:R-HSA-8982637 "Opsins binds G alpha-t" +xref: Reactome:R-HSA-8982640 "G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t)" +xref: Reactome:R-HSA-939265 "Activation of Rap1 by membrane-associated GEFs" +is_a: GO:0051020 ! GTPase binding +is_a: GO:0098772 ! molecular function regulator + +[Term] +id: GO:0005086 +name: ARF guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +xref: Reactome:R-HSA-350769 "trans-Golgi Network Coat Activation" +xref: Reactome:R-HSA-5623508 "GBF1 stimulates nucleotide exchange on ARF4" +xref: Reactome:R-HSA-6811414 "GBF1 stimulates nucleotide exchange on ARF" +xref: Reactome:R-HSA-6811418 "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane" +is_a: GO:0005085 ! guanyl-nucleotide exchange factor activity + +[Term] +id: GO:0005087 +name: Ran guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +synonym: "RCC1" EXACT [] +xref: Reactome:R-HSA-180687 "Conversion of Ran-GDP to Ran-GTP" +xref: Wikipedia:RCC1 +is_a: GO:0005088 ! Ras guanyl-nucleotide exchange factor activity +is_a: GO:0008536 ! Ran GTPase binding + +[Term] +id: GO:0005088 +name: Ras guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +xref: Reactome:R-HSA-109807 "GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS" +xref: Reactome:R-HSA-109817 "GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS" +xref: Reactome:R-HSA-1225951 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)" +xref: Reactome:R-HSA-1225957 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants)" +xref: Reactome:R-HSA-1250383 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4" +xref: Reactome:R-HSA-1250463 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers" +xref: Reactome:R-HSA-1250498 "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers." +xref: Reactome:R-HSA-1306972 "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers" +xref: Reactome:R-HSA-1433471 "Activation of RAS by p-KIT bound SOS1" +xref: Reactome:R-HSA-177938 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)" +xref: Reactome:R-HSA-177945 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)" +xref: Reactome:R-HSA-186834 "Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos)" +xref: Reactome:R-HSA-210977 "Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos)" +xref: Reactome:R-HSA-2179407 "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)" +xref: Reactome:R-HSA-2424477 "SOS mediated nucleotide exchange of RAS (SHC)" +xref: Reactome:R-HSA-392054 "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras" +xref: Reactome:R-HSA-442732 "NMDA-activated RASGRF1 activates RAS" +xref: Reactome:R-HSA-5637806 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII)" +xref: Reactome:R-HSA-5637808 "SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII)" +xref: Reactome:R-HSA-5654392 "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654402 "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654413 "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654426 "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654600 "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654618 "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654647 "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5654663 "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5655241 "Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5655277 "Activated FGFR3 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5655326 "Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5655347 "Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-5672965 "RAS GEFs promote RAS nucleotide exchange" +xref: Reactome:R-HSA-5686071 "GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS" +xref: Reactome:R-HSA-5686318 "GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS" +xref: Reactome:R-HSA-8853307 "FGFR3 fusions:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange" +xref: Reactome:R-HSA-9026891 "NTRK2 activates RAS signaling through SHC1" +xref: Reactome:R-HSA-9029158 "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS" +xref: Reactome:R-HSA-9032067 "NTRK2 activates RAS signaling through FRS2" +is_a: GO:0005085 ! guanyl-nucleotide exchange factor activity +is_a: GO:0017016 ! Ras GTPase binding + +[Term] +id: GO:0005089 +name: Rho guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +subset: goslim_chembl +synonym: "Rho guanine nucleotide exchange factor" EXACT [] +synonym: "RhoGEF" EXACT [] +xref: Reactome:R-HSA-194518 "RhoA is activated by nucleotide exchange and inhibits axonal growth" +xref: Reactome:R-HSA-194913 "GEFs activate Rho GTPase:GDP" +xref: Reactome:R-HSA-416588 "Activation of Rho by LARG and PDZ-RhoGEF" +xref: Reactome:R-HSA-418850 "Activation of Cdc42" +xref: Reactome:R-HSA-418856 "Activation of Rac1" +xref: Reactome:R-HSA-419166 "GEFs activate RhoA,B,C" +is_a: GO:0005088 ! Ras guanyl-nucleotide exchange factor activity +is_a: GO:0017048 ! Rho GTPase binding + +[Term] +id: GO:0005090 +name: Sar guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Sar family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +comment: Note that the name Sar derives from 'secretion-associated, Ras-related'. +is_a: GO:0005085 ! guanyl-nucleotide exchange factor activity +is_a: GO:0030695 ! GTPase regulator activity + +[Term] +id: GO:0005091 +name: guanyl-nucleotide exchange factor adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07, GOC:vw] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +is_a: GO:0030695 ! GTPase regulator activity + +[Term] +id: GO:0005092 +name: GDP-dissociation inhibitor activity +namespace: molecular_function +def: "Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding." [GOC:mah] +synonym: "GDI" EXACT [] +is_a: GO:0030695 ! GTPase regulator activity +relationship: positively_regulates GO:0019003 ! GDP binding + +[Term] +id: GO:0005093 +name: Rab GDP-dissociation inhibitor activity +namespace: molecular_function +def: "Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding." [GOC:mah] +is_a: GO:0005092 ! GDP-dissociation inhibitor activity + +[Term] +id: GO:0005094 +name: Rho GDP-dissociation inhibitor activity +namespace: molecular_function +def: "Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding." [GOC:mah] +is_a: GO:0005092 ! GDP-dissociation inhibitor activity + +[Term] +id: GO:0005095 +name: GTPase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate." [GOC:ai] +synonym: "GIP" BROAD [] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0030695 ! GTPase regulator activity +relationship: negatively_regulates GO:0003924 ! GTPase activity +relationship: part_of GO:0034260 ! negative regulation of GTPase activity + +[Term] +id: GO:0005096 +name: GTPase activator activity +namespace: molecular_function +alt_id: GO:0005097 +alt_id: GO:0005098 +alt_id: GO:0005099 +alt_id: GO:0005100 +alt_id: GO:0005101 +alt_id: GO:0008060 +alt_id: GO:0017123 +alt_id: GO:0030675 +alt_id: GO:0046582 +def: "Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP." [GOC:mah] +comment: Note that the name Sar derives from 'secretion-associated, Ras-related'. +synonym: "ARF GAP activity" NARROW [GOC:pg] +synonym: "ARF GTPase activator activity" NARROW [] +synonym: "GAP activity" EXACT [] +synonym: "Rab GAP activity" NARROW [GOC:pg] +synonym: "Rab GTPase activator activity" NARROW [] +synonym: "Rac GAP activity" NARROW [GOC:pg] +synonym: "Rac GTPase activator activity" NARROW [] +synonym: "Ral GAP activity" NARROW [GOC:pg] +synonym: "Ral GTPase activator activity" NARROW [] +synonym: "Ran GAP activity" NARROW [GOC:pg] +synonym: "Ran GTPase activator activity" NARROW [] +synonym: "RanGAP" NARROW [] +synonym: "Rap GAP activity" NARROW [GOC:pg] +synonym: "Rap GTPase activator activity" NARROW [] +synonym: "Ras GAP activity" NARROW [GOC:pg] +synonym: "Ras GTPase activator activity" NARROW [] +synonym: "Rho GAP activity" NARROW [GOC:pg] +synonym: "Rho GTPase activator activity" NARROW [] +synonym: "Sar GAP activity" NARROW [GOC:pg] +synonym: "Sar GTPase activator activity" NARROW [] +xref: Reactome:R-HSA-194922 "GAPs inactivate Rho GTPase:GTP by hydrolysis" +xref: Reactome:R-HSA-392513 "Rap1 signal termination by Rap1GAPs" +xref: Reactome:R-HSA-399935 "Inactivation of R-Ras by Sema3A-Plexin-A GAP activity" +xref: Reactome:R-HSA-4093339 "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it" +xref: Reactome:R-HSA-416546 "Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity" +xref: Reactome:R-HSA-416559 "Inactivation of Rho-GTP by p190RhoGAP" +xref: Reactome:R-HSA-428522 "Inactivation of RAC1" +xref: Reactome:R-HSA-428533 "Inactivation of CDC42" +xref: Reactome:R-HSA-5638007 "RP2 activates the GTPase activity of ARL3" +xref: Reactome:R-HSA-8985594 "MYO9B inactivates RHOA" +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0030695 ! GTPase regulator activity +relationship: part_of GO:0043547 ! positive regulation of GTPase activity +relationship: positively_regulates GO:0003924 ! GTPase activity + +[Term] +id: GO:0005102 +name: signaling receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:bf, GOC:ceb, ISBN:0198506732] +comment: Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'. +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_plant +synonym: "receptor binding" BROAD [] +synonym: "receptor ligand" NARROW [] +synonym: "receptor-associated protein activity" RELATED [] +xref: Wikipedia:Ligand_(biochemistry) +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0005104 +name: fibroblast growth factor receptor binding +namespace: molecular_function +alt_id: GO:0001521 +alt_id: GO:0005162 +def: "Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR)." [GOC:ceb] +comment: Note that branchless is the Drosophila gene encoding fibroblast growth factor. +synonym: "FGF receptor binding" EXACT [] +synonym: "FGFR binding" EXACT [] +synonym: "FGFR ligand" NARROW [] +synonym: "fibroblast growth factor" BROAD [] +synonym: "fibroblast growth factor receptor ligand" NARROW [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005105 +name: type 1 fibroblast growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the type 1 fibroblast growth factor receptor (FGFR1)." [GOC:ceb, GOC:fb_curators] +comment: Note that breathless is the Drosophila gene encoding the type 1 fibroblast growth factor receptor (FGFR1). +synonym: "breathless binding" NARROW [] +synonym: "breathless ligand" NARROW [] +synonym: "FGFR1 binding" BROAD [] +synonym: "FGFR1 ligand" NARROW [] +synonym: "type 1 fibroblast growth factor receptor ligand" NARROW [] +is_a: GO:0005104 ! fibroblast growth factor receptor binding + +[Term] +id: GO:0005106 +name: obsolete ephrin +namespace: molecular_function +def: "OBSOLETE. A class of proteins that interact with the ephrin receptors." [GOC:ai, ISBN:0198506732] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "ephrin" EXACT [] +is_obsolete: true +consider: GO:0046875 + +[Term] +id: GO:0005107 +name: obsolete GPI-linked ephrin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "GPI-linked ephrin" EXACT [] +is_obsolete: true +consider: GO:0046658 +consider: GO:0046875 + +[Term] +id: GO:0005108 +name: obsolete transmembrane ephrin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "transmembrane ephrin" EXACT [] +is_obsolete: true +consider: GO:0005887 +consider: GO:0046875 + +[Term] +id: GO:0005109 +name: frizzled binding +namespace: molecular_function +alt_id: GO:0005110 +def: "Interacting selectively and non-covalently with a frizzled (fz) receptor." [GOC:ceb, PR:000001315] +subset: goslim_chembl +synonym: "frizzled ligand" NARROW [] +synonym: "frizzled-2 binding" NARROW [] +synonym: "frizzled-2 ligand" NARROW [] +synonym: "fz binding" EXACT [] +synonym: "fz ligand" NARROW [] +synonym: "fz2 binding" NARROW [] +synonym: "fz2 ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0005111 +name: type 2 fibroblast growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the type 2 fibroblast growth factor receptor (FGFR2)." [GOC:fb_curators] +comment: Note that heartless is the Drosophila gene encoding the type 2 fibroblast growth factor receptor (FGFR2). +synonym: "FGFR2 binding" EXACT [] +synonym: "FGFR2 ligand" NARROW [] +synonym: "heartless binding" EXACT [] +synonym: "heartless ligand" NARROW [] +synonym: "type 2 fibroblast growth factor receptor ligand" NARROW [] +is_a: GO:0005104 ! fibroblast growth factor receptor binding + +[Term] +id: GO:0005112 +name: Notch binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor." [GOC:ceb] +synonym: "N binding" EXACT [] +synonym: "N ligand" NARROW [] +synonym: "Notch ligand" NARROW [] +synonym: "Notch receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005113 +name: patched binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the patched (ptc) protein, a receptor for hedgehog proteins." [GOC:ceb, PMID:11731473] +synonym: "patched ligand" NARROW [] +synonym: "ptc binding" EXACT [] +synonym: "ptc ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005114 +name: type II transforming growth factor beta receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type II transforming growth factor beta receptor." [GOC:ceb, GOC:mah, PMID:11252892] +synonym: "punt binding" NARROW [] +synonym: "punt ligand" NARROW [] +synonym: "TGF-beta type II binding" EXACT [] +synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] +synonym: "transforming growth factor beta receptor type II binding" EXACT [] +synonym: "type II TGF-beta binding" EXACT [] +is_a: GO:0005160 ! transforming growth factor beta receptor binding + +[Term] +id: GO:0005115 +name: receptor tyrosine kinase-like orphan receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the receptor tyrosine kinase-like orphan receptor (Ror)." [GOC:ceb, GOC:vw] +synonym: "receptor tyrosine kinase-like orphan receptor ligand" NARROW [] +synonym: "Ror binding" BROAD [] +synonym: "Ror ligand" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005117 +name: wishful thinking binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with wishful thinking (Wit), a type II bone morphogenic protein receptor." [GOC:ceb, PMID:11856529] +synonym: "SE20 receptor binding" NARROW [] +synonym: "wishful thinking ligand" NARROW [] +synonym: "Wit binding" EXACT [] +synonym: "Wit ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005118 +name: sevenless binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the sevenless (sev) protein, a receptor tyrosine kinase." [GOC:ceb, PMID:3151175] +synonym: "sev binding" EXACT [] +synonym: "sev ligand" NARROW [] +synonym: "sevenless ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005119 +name: smoothened binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals." [GOC:ceb, PMID:11731473] +synonym: "smo binding" EXACT [] +synonym: "smo ligand" NARROW [] +synonym: "smoothened ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0005121 +name: Toll binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the Toll protein, a transmembrane receptor." [GOC:ceb] +synonym: "Tl binding" EXACT [] +synonym: "Toll ligand" NARROW [] +synonym: "Toll receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005122 +name: torso binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase." [GOC:ceb, PMID:2927509] +synonym: "tor binding" EXACT [] +synonym: "tor ligand" NARROW [] +synonym: "torso ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005123 +name: death receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD)." [GOC:ceb, GOC:rl, PMID:15654015] +subset: goslim_chembl +synonym: "APO binding" NARROW [GOC:rl] +synonym: "death receptor adaptor protein activity" RELATED [] +synonym: "death receptor interacting protein activity" RELATED [] +synonym: "death receptor ligand" NARROW [] +synonym: "death receptor-associated factor activity" RELATED [] +synonym: "DR binding" NARROW [GOC:rl] +synonym: "EDAR binding" NARROW [GOC:rl] +synonym: "FAS binding" NARROW [GOC:rl] +synonym: "KILLER binding" NARROW [GOC:rl] +synonym: "NGFR binding" NARROW [GOC:rl] +synonym: "TNFR1 binding" NARROW [GOC:rl] +synonym: "TRAIL binding" NARROW [GOC:rl] +is_a: GO:0032813 ! tumor necrosis factor receptor superfamily binding + +[Term] +id: GO:0005124 +name: scavenger receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles." [GOC:ceb] +synonym: "scavenger receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005125 +name: cytokine activity +namespace: molecular_function +def: "The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells." [ISBN:0198599471, PMID:11530802] +subset: goslim_chembl +synonym: "autocrine activity" RELATED [GOC:rl] +synonym: "paracrine activity" RELATED [GOC:rl] +is_a: GO:0048018 ! receptor ligand activity +property_value: RO:0002161 NCBITaxon:4751 +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19116 xsd:anyURI + +[Term] +id: GO:0005126 +name: cytokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cytokine receptor." [GOC:mah, GOC:vw] +synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor binding" EXACT [GOC:add, GOC:mah] +synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005127 +name: ciliary neurotrophic factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the ciliary neurotrophic factor receptor." [GOC:ai] +synonym: "ciliary neurotrophic factor" NARROW [] +synonym: "ciliary neurotrophic factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005128 +name: erythropoietin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the erythropoietin receptor." [GOC:ai] +synonym: "erythropoietin" NARROW [] +synonym: "erythropoietin receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005129 +name: granulocyte macrophage colony-stimulating factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor receptor." [GOC:ai] +synonym: "GM-CSF receptor binding" EXACT [GOC:vk] +synonym: "GM-CSF receptor ligand" NARROW [] +synonym: "GMC-SF receptor ligand" NARROW [] +synonym: "granulocyte macrophage colony stimulating factor receptor binding" EXACT [] +synonym: "granulocyte macrophage colony-stimulating factor" NARROW [] +synonym: "granulocyte macrophage colony-stimulating factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005130 +name: granulocyte colony-stimulating factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the granulocyte colony-stimulating factor receptor." [GOC:ai] +synonym: "G-CSF receptor ligand" EXACT [] +synonym: "GC-SF receptor ligand" EXACT [] +synonym: "granulocyte colony stimulating factor receptor binding" EXACT [] +synonym: "granulocyte colony-stimulating factor" NARROW [] +synonym: "granulocyte colony-stimulating factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005131 +name: growth hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the growth hormone receptor." [GOC:ai] +synonym: "growth hormone" NARROW [] +synonym: "growth hormone receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0051427 ! hormone receptor binding + +[Term] +id: GO:0005132 +name: type I interferon receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2)." [GOC:ai, GOC:signaling, PMID:17502368] +synonym: "IFNAR binding" RELATED [PMID:17502368] +synonym: "IFNAR1 binding" NARROW [PR:000008922] +synonym: "IFNAR2 binding" NARROW [PR:000008923] +synonym: "interferon-alpha/beta" NARROW [] +synonym: "interferon-alpha/beta receptor binding" EXACT [PR:000008922, PR:000008923] +synonym: "interferon-alpha/beta receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0005133 +name: interferon-gamma receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interferon-gamma receptor." [GOC:ai] +synonym: "interferon-gamma" NARROW [] +synonym: "interferon-gamma receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005134 +name: interleukin-2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-2 receptor." [GOC:ai] +synonym: "IL-2" NARROW [] +synonym: "interleukin-2 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005135 +name: interleukin-3 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-3 receptor." [GOC:ai] +synonym: "IL-3" NARROW [] +synonym: "interleukin-3 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005136 +name: interleukin-4 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-4 receptor." [GOC:ai] +synonym: "IL-4" NARROW [] +synonym: "interleukin-4 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005137 +name: interleukin-5 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-5 receptor." [GOC:ai] +subset: goslim_chembl +synonym: "IL-5" NARROW [] +synonym: "interleukin-5 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005138 +name: interleukin-6 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-6 receptor." [GOC:ai] +subset: goslim_chembl +synonym: "IL-6" NARROW [] +synonym: "interleukin-6 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005139 +name: interleukin-7 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-7 receptor." [GOC:ai] +synonym: "IL-7" NARROW [] +synonym: "interleukin-7 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005140 +name: interleukin-9 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-9 receptor." [GOC:ai] +synonym: "IL-9" NARROW [] +synonym: "interleukin-9 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005141 +name: interleukin-10 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-10 receptor." [GOC:ai] +synonym: "IL-10" NARROW [] +synonym: "interleukin-10 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005142 +name: interleukin-11 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-11 receptor." [GOC:ai] +synonym: "IL-11" NARROW [] +synonym: "interleukin-11 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005143 +name: interleukin-12 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-12 receptor." [GOC:ai] +synonym: "IL-12" NARROW [] +synonym: "interleukin-12 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005144 +name: interleukin-13 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-13 receptor." [GOC:ai] +synonym: "IL-13" NARROW [] +synonym: "interleukin-13 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005145 +name: interleukin-14 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-14 receptor." [GOC:ai] +synonym: "IL-14" NARROW [] +synonym: "interleukin-14 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005146 +name: leukemia inhibitory factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the leukemia inhibitory factor receptor." [GOC:ai] +synonym: "leukemia inhibitory factor" NARROW [] +synonym: "leukemia inhibitory factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005147 +name: oncostatin-M receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the oncostatin-M receptor." [GOC:ai] +synonym: "oncostatin-M" NARROW [] +synonym: "oncostatin-M receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005148 +name: prolactin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the prolactin receptor." [GOC:ai] +synonym: "prolactin" NARROW [] +synonym: "prolactin receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005149 +name: interleukin-1 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-1 receptor." [GOC:go_curators] +synonym: "IL-1" NARROW [] +synonym: "interleukin-1 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005150 +name: interleukin-1, type I receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Type I interleukin-1 receptor." [GOC:ai] +synonym: "IL-1 type I" NARROW [] +synonym: "interleukin-1, type I receptor ligand" NARROW [] +is_a: GO:0005149 ! interleukin-1 receptor binding + +[Term] +id: GO:0005151 +name: interleukin-1, type II receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Type II interleukin-1 receptor." [GOC:ai] +synonym: "IL-1 type II" NARROW [] +synonym: "interleukin-1, type II receptor ligand" NARROW [] +is_a: GO:0005149 ! interleukin-1 receptor binding + +[Term] +id: GO:0005152 +name: interleukin-1 receptor antagonist activity +namespace: molecular_function +def: "Blocks the binding of interleukin-1 to the interleukin-1 receptor complex." [GOC:ebc] +synonym: "IL-1ra" EXACT [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0019966 ! interleukin-1 binding +is_a: GO:0048019 ! receptor antagonist activity +relationship: part_of GO:0001960 ! negative regulation of cytokine-mediated signaling pathway + +[Term] +id: GO:0005153 +name: interleukin-8 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-8 receptor." [GOC:go_curators] +subset: goslim_chembl +synonym: "IL-8" NARROW [] +synonym: "interleukin-8 receptor ligand" NARROW [] +is_a: GO:0045236 ! CXCR chemokine receptor binding + +[Term] +id: GO:0005154 +name: epidermal growth factor receptor binding +namespace: molecular_function +alt_id: GO:0008185 +def: "Interacting selectively and non-covalently with the epidermal growth factor receptor." [GOC:ai] +subset: goslim_chembl +synonym: "EGF" NARROW [] +synonym: "EGF receptor binding" EXACT [] +synonym: "EGF receptor ligand" NARROW [] +synonym: "EGFR binding" EXACT [] +synonym: "epidermal growth factor" NARROW [] +synonym: "epidermal growth factor receptor ligand" NARROW [] +synonym: "TGF-alpha receptor binding" EXACT [] +synonym: "TGFalpha receptor binding" EXACT [] +synonym: "transforming growth factor alpha" NARROW [] +synonym: "transforming growth factor alpha receptor binding" EXACT [] +synonym: "transforming growth factor alpha receptor ligand" NARROW [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005155 +name: obsolete epidermal growth factor receptor activating ligand activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because it represents both a biological process and a molecular function. +synonym: "EGF receptor activating ligand activity" EXACT [] +synonym: "EGFR activating ligand activity" EXACT [] +synonym: "epidermal growth factor receptor activating ligand activity" EXACT [] +is_obsolete: true +replaced_by: GO:0005154 +consider: GO:0030297 +consider: GO:0045741 + +[Term] +id: GO:0005156 +name: obsolete epidermal growth factor receptor inhibiting ligand activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because it represents both a biological process and a molecular function. +synonym: "EGF receptor inhibiting ligand activity" EXACT [] +synonym: "EGFR inhibiting ligand activity" EXACT [] +synonym: "epidermal growth factor receptor inhibiting ligand activity" EXACT [] +is_obsolete: true +replaced_by: GO:0005154 +consider: GO:0007175 +consider: GO:0030293 + +[Term] +id: GO:0005157 +name: macrophage colony-stimulating factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor." [GOC:ai] +synonym: "M-CSF receptor binding" EXACT [GOC:vk] +synonym: "macrophage colony stimulating factor receptor binding" EXACT [] +synonym: "macrophage colony-stimulating factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005158 +name: insulin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the insulin receptor." [GOC:ai] +synonym: "insulin receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0005159 +name: insulin-like growth factor receptor binding +namespace: molecular_function +alt_id: GO:0005067 +def: "Interacting selectively and non-covalently with the insulin-like growth factor receptor." [GOC:jl] +synonym: "IGF receptor binding" EXACT [] +synonym: "insulin-like growth factor" NARROW [] +synonym: "insulin-like growth factor receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005160 +name: transforming growth factor beta receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the transforming growth factor beta receptor." [GOC:ai] +synonym: "activin" RELATED [] +synonym: "inhibin" RELATED [] +synonym: "TGF-beta receptor binding" EXACT [] +synonym: "TGFbeta receptor binding" EXACT [] +synonym: "transforming growth factor beta" NARROW [] +synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] +synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] +synonym: "transforming growth factor beta receptor anchoring activity" RELATED [] +synonym: "transforming growth factor beta receptor ligand" NARROW [] +xref: Reactome:R-HSA-170861 "Dimeric TGF-beta-1 binds to the receptor" +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005161 +name: platelet-derived growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the platelet-derived growth factor receptor." [GOC:ai] +synonym: "PDGF" NARROW [] +synonym: "PDGF receptor binding" EXACT [] +synonym: "PDGFR binding" EXACT [] +synonym: "platelet-derived growth factor" NARROW [] +synonym: "platelet-derived growth factor receptor ligand" NARROW [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005163 +name: nerve growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the nerve growth factor receptor." [GOC:ai, PMID:15654015] +synonym: "nerve growth factor receptor ligand" NARROW [] +synonym: "neurotrophin" NARROW [] +synonym: "NGF receptor binding" EXACT [] +is_a: GO:0005123 ! death receptor binding +is_a: GO:0005165 ! neurotrophin receptor binding + +[Term] +id: GO:0005164 +name: tumor necrosis factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the tumor necrosis factor receptor." [GOC:ai] +subset: goslim_chembl +synonym: "TNF receptor binding" EXACT [] +synonym: "tumor necrosis factor" NARROW [] +synonym: "tumor necrosis factor receptor ligand" NARROW [] +is_a: GO:0032813 ! tumor necrosis factor receptor superfamily binding + +[Term] +id: GO:0005165 +name: neurotrophin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neurotrophin receptor." [GOC:ai] +synonym: "neurotrophin" NARROW [] +synonym: "neurotrophin receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005166 +name: neurotrophin p75 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the neurotrophin p75 receptor." [GOC:ai] +synonym: "neurotrophin p75 receptor ligand" NARROW [] +is_a: GO:0005165 ! neurotrophin receptor binding + +[Term] +id: GO:0005167 +name: neurotrophin TRK receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neurotrophin TRK receptor." [GOC:ai] +synonym: "neurotrophin TRK receptor ligand" NARROW [] +is_a: GO:0005165 ! neurotrophin receptor binding + +[Term] +id: GO:0005168 +name: neurotrophin TRKA receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the neurotrophin TRKA receptor." [GOC:ai] +synonym: "neurotrophin TRKA receptor ligand" NARROW [] +is_a: GO:0005167 ! neurotrophin TRK receptor binding + +[Term] +id: GO:0005169 +name: neurotrophin TRKB receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the neurotrophin TRKB receptor." [GOC:ai] +synonym: "neurotrophin TRKB receptor ligand" NARROW [] +is_a: GO:0005167 ! neurotrophin TRK receptor binding + +[Term] +id: GO:0005170 +name: neurotrophin TRKC receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the neurotrophin TRKC receptor." [GOC:ai] +synonym: "neurotrophin TRKC receptor ligand" NARROW [] +is_a: GO:0005167 ! neurotrophin TRK receptor binding + +[Term] +id: GO:0005171 +name: hepatocyte growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the hepatocyte growth factor receptor." [GOC:ai] +synonym: "hepatocyte growth factor" NARROW [] +synonym: "hepatocyte growth factor receptor ligand" NARROW [] +synonym: "HGF receptor binding" EXACT [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005172 +name: vascular endothelial growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any vascular endothelial growth factor receptor." [GOC:ai] +synonym: "vascular endothelial growth factor" NARROW [] +synonym: "vascular endothelial growth factor receptor ligand" NARROW [] +synonym: "VEGF receptor binding" EXACT [] +synonym: "VEGFR binding" EXACT [] +is_a: GO:0005126 ! cytokine receptor binding +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0005173 +name: stem cell factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor." [GOC:jl, PMID:10698217] +synonym: "KIT binding" NARROW [] +synonym: "SCF" NARROW [] +synonym: "SCFR binding" EXACT [] +synonym: "stem cell factor" NARROW [] +synonym: "stem cell factor receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0005174 +name: CD40 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes." [GOC:jl, ISBN:0120781859] +is_a: GO:0032813 ! tumor necrosis factor receptor superfamily binding + +[Term] +id: GO:0005175 +name: CD27 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CD27, a receptor found on the surface of T cells and some B cells and NK cells." [GOC:jl, ISBN:0120781859] +is_a: GO:0032813 ! tumor necrosis factor receptor superfamily binding + +[Term] +id: GO:0005176 +name: ErbB-2 class receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the protein-tyrosine kinase receptor Neu/ErbB-2/HER2." [GOC:jl] +synonym: "ErbB-2 class receptor ligand" NARROW [] +synonym: "HER2 receptor binding" EXACT [] +synonym: "HER2 receptor ligand" NARROW [] +synonym: "Neu receptor binding" EXACT [] +synonym: "Neu receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005177 +name: obsolete neuroligin +namespace: molecular_function +def: "OBSOLETE. A class of ligands for neurexins." [GOC:ai] +synonym: "neuroligin" EXACT [] +is_obsolete: true +consider: GO:0042043 + +[Term] +id: GO:0005178 +name: integrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an integrin." [GOC:ceb] +subset: goslim_chembl +synonym: "integrin ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0044877 ! protein-containing complex binding +is_a: GO:0050839 ! cell adhesion molecule binding + +[Term] +id: GO:0005179 +name: hormone activity +namespace: molecular_function +def: "The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process." [GOC:dph, GOC:mah, ISBN:0198506732] +comment: Also consider annotating to 'receptor agonist activity ; GO:0048018'. +subset: goslim_chembl +synonym: "cAMP generating peptide activity" NARROW [] +synonym: "glycopeptide hormone" NARROW [] +synonym: "lipopeptide hormone" NARROW [] +synonym: "peptide hormone" NARROW [] +is_a: GO:0048018 ! receptor ligand activity + +[Term] +id: GO:0005180 +name: obsolete peptide hormone +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a type of hormone rather than a molecular function. +synonym: "peptide hormone" EXACT [] +is_obsolete: true +consider: GO:0005179 + +[Term] +id: GO:0005181 +name: obsolete glycopeptide hormone +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a type of hormone rather than a molecular function. +synonym: "glycopeptide hormone" EXACT [] +is_obsolete: true +consider: GO:0005179 + +[Term] +id: GO:0005182 +name: obsolete lipopeptide hormone +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a type of hormone rather than a molecular function. +synonym: "lipopeptide hormone" EXACT [] +is_obsolete: true +consider: GO:0005179 + +[Term] +id: GO:0005183 +name: gonadotropin hormone-releasing hormone activity +namespace: molecular_function +def: "The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary." [ISBN:0198506732, PMID:11026571, Wikipedia:Gonadotropin-releasing_hormone] +synonym: "GnRH activity" EXACT [ISBN:0198506732] +synonym: "gonadotrophin hormone-releasing hormone activity" EXACT [GOC:dph] +synonym: "LH/FSH-RF" EXACT [ISBN:0198506732] +synonym: "LHRH activity" EXACT [ISBN:0198506732] +synonym: "luteinizing hormone-releasing factor activity" EXACT [ISBN:0198506732] +synonym: "luteinizing hormone-releasing hormone activity" EXACT [ISBN:0198506732] +synonym: "luteinizing hormone/follicle-stimulating hormone releasing factor activity" EXACT [ISBN:0198506732] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0005184 +name: neuropeptide hormone activity +namespace: molecular_function +def: "The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones." [GOC:mah] +subset: goslim_chembl +synonym: "neurohormone" EXACT [] +xref: Wikipedia:Neurohormone +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0005185 +name: neurohypophyseal hormone activity +namespace: molecular_function +def: "The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin." [GOC:mah, PMID:19243634] +synonym: "neurohypophysial hormone activity" EXACT [GOC:mah] +is_a: GO:0005184 ! neuropeptide hormone activity + +[Term] +id: GO:0005186 +name: pheromone activity +namespace: molecular_function +def: "The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant." [GOC:sgd_curators, ISBN:0198506732] +comment: Also consider annotating to 'receptor agonist activity ; GO:0048018'. +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0005187 +name: obsolete storage protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes a cellular location rather than a function. +synonym: "storage protein" EXACT [] +is_obsolete: true +replaced_by: GO:0045735 + +[Term] +id: GO:0005188 +name: obsolete larval serum protein (sensu Insecta) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "arylphorin" NARROW [] +synonym: "larval serum protein (sensu Insecta)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005189 +name: obsolete milk protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "milk protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005190 +name: obsolete seminal fluid protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "seminal fluid protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005191 +name: obsolete acidic epididymal glycoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes modification and presence in body fluids rather than an activity. +synonym: "acidic epididymal glycoprotein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005192 +name: obsolete urinary protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "urinary protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005193 +name: obsolete major urinary protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "major urinary protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005194 +name: obsolete cell adhesion molecule activity +namespace: molecular_function +def: "OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix." [ISBN:0198506732] +comment: This term was made obsolete because it represents gene products involved in the biological process of cell adhesion. +synonym: "cell adhesion molecule activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 +consider: GO:0007155 +consider: GO:0016021 +consider: GO:0030246 +consider: GO:0050839 +consider: GO:0098631 + +[Term] +id: GO:0005198 +name: structural molecule activity +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell." [GOC:mah, GOC:vw] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0005199 +name: structural constituent of cell wall +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a cell wall." [GOC:mah] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0005618 ! cell wall +relationship: occurs_in GO:0005618 ! cell wall +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0005200 +name: structural constituent of cytoskeleton +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a cytoskeletal structure." [GOC:mah] +subset: goslim_drosophila +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0005856 ! cytoskeleton +intersection_of: part_of GO:0007010 ! cytoskeleton organization +relationship: occurs_in GO:0005856 ! cytoskeleton +relationship: part_of GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0005201 +name: extracellular matrix structural constituent +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the extracellular matrix." [GOC:mah] +comment: Extracellular matrix glycoproteins may be annotated to this term. PMID:24443019 +subset: goslim_drosophila +synonym: "core extracellular matrix" BROAD [] +synonym: "core matrisome" BROAD [] +synonym: "extracellular matrix glycoprotein" NARROW [] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0031012 ! extracellular matrix +relationship: occurs_in GO:0031012 ! extracellular matrix + +[Term] +id: GO:0005202 +name: obsolete collagen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "collagen" EXACT [] +is_obsolete: true +consider: GO:0005581 + +[Term] +id: GO:0005203 +name: obsolete proteoglycan +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function. +synonym: "proteoglycan" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005204 +name: obsolete chondroitin sulfate proteoglycan +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function. +synonym: "chondroitin sulfate proteoglycan" EXACT [] +synonym: "chondroitin sulphate proteoglycan" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005205 +name: obsolete chondroitin sulfate/dermatan sulfate proteoglycan +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function. +synonym: "chondroitin sulfate/dermatan sulfate proteoglycan" EXACT [] +synonym: "chondroitin sulphate/dermatan sulphate proteoglycan" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005206 +name: obsolete heparin sulfate proteoglycan +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "heparin sulfate proteoglycan" EXACT [] +synonym: "heparin sulphate proteoglycan" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005207 +name: obsolete extracellular matrix glycoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes localization and modification rather than activity. +synonym: "extracellular matrix glycoprotein" EXACT [] +is_obsolete: true +consider: GO:0005201 + +[Term] +id: GO:0005208 +name: obsolete amyloid protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "amyloid protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005209 +name: obsolete plasma protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes presence in body fluids rather than an activity. +synonym: "plasma protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005211 +name: obsolete plasma glycoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes modification and presence in body fluids rather than an activity. +synonym: "plasma glycoprotein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005212 +name: structural constituent of eye lens +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the lens of an eye." [GOC:mah] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0005213 +name: structural constituent of egg chorion +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:sensu] +synonym: "structural constituent of chorion" BROAD [] +synonym: "structural protein of chorion" NARROW [] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0042600 ! egg chorion +relationship: occurs_in GO:0042600 ! egg chorion + +[Term] +id: GO:0005214 +name: structural constituent of chitin-based cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0042302 ! structural constituent of cuticle + +[Term] +id: GO:0005215 +name: transporter activity +namespace: molecular_function +alt_id: GO:0005478 +def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:ai, GOC:dgf] +comment: Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules. +subset: gocheck_do_not_annotate +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +synonym: "carrier" RELATED [] +xref: EC:7 +xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion" +xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol" +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0005216 +name: ion channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size)." [GOC:cy, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0015267 ! channel activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity + +[Term] +id: GO:0005217 +name: intracellular ligand-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015276 ! ligand-gated ion channel activity + +[Term] +id: GO:0005219 +name: ryanodine-sensitive calcium-release channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:dph, GOC:tb] +synonym: "caffeine-sensitive calcium-release channel" RELATED [] +synonym: "ryanodine receptor" NARROW [] +xref: Reactome:R-HSA-2855020 "RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol" +is_a: GO:0015278 ! calcium-release channel activity + +[Term] +id: GO:0005220 +name: inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +namespace: molecular_function +alt_id: GO:0008095 +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts." [GOC:mah, GOC:signaling, PMID:8660280, Wikipedia:Inositol_trisphosphate_receptor] +synonym: "inositol-1,4,5-trisphosphate receptor activity" EXACT [] +synonym: "InsP3 receptor" EXACT [GOC:bf] +synonym: "IP3 receptor activity" EXACT [] +is_a: GO:0015278 ! calcium-release channel activity +relationship: has_part GO:0070679 ! inositol 1,4,5 trisphosphate binding +relationship: part_of GO:0048016 ! inositol phosphate-mediated signaling + +[Term] +id: GO:0005221 +name: intracellular cyclic nucleotide activated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] +xref: Reactome:R-HSA-2514867 "cGMP:CNG transports Na+ and Ca2+ into the rod outer segment" +is_a: GO:0005217 ! intracellular ligand-gated ion channel activity +is_a: GO:0043855 ! cyclic nucleotide-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0005222 +name: intracellular cAMP-activated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] +synonym: "HCN channel activity" BROAD [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "hyperpolarization-activated cyclic nucleotide-gated channel activity" BROAD [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "intracellular 3',5' cAMP activated cation channel activity" EXACT [] +synonym: "intracellular 3',5'-cAMP activated cation channel activity" EXACT [] +synonym: "intracellular adenosine 3',5'-cyclophosphate activated cation channel activity" EXACT [] +synonym: "intracellular cAMP activated cation channel activity" EXACT [] +synonym: "intracellular cyclic AMP activated cation channel activity" EXACT [] +is_a: GO:0005221 ! intracellular cyclic nucleotide activated cation channel activity + +[Term] +id: GO:0005223 +name: intracellular cGMP-activated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] +synonym: "intracellular cGMP activated cation channel activity" EXACT [] +is_a: GO:0005221 ! intracellular cyclic nucleotide activated cation channel activity + +[Term] +id: GO:0005225 +name: volume-sensitive anion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell." [GOC:dph, GOC:tb] +synonym: "volume-regulated channel" BROAD [] +xref: Reactome:R-HSA-8941543 "VRAC heteromer transports I-, Cl- from cytosol to extracellular region" +is_a: GO:0005253 ! anion channel activity + +[Term] +id: GO:0005227 +name: calcium activated cation channel activity +namespace: molecular_function +def: "Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport] +synonym: "intracellular calcium-activated potassium channel" NARROW [] +synonym: "polycystin" NARROW [] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0022839 ! ion gated channel activity + +[Term] +id: GO:0005228 +name: intracellular sodium activated potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification." [GOC:mtg_transport, PMID:12628167] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0022839 ! ion gated channel activity + +[Term] +id: GO:0005229 +name: intracellular calcium activated chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] +xref: Reactome:R-HSA-2684901 "ANOs transport cytosolic Cl- to extracellular region" +xref: Reactome:R-HSA-2744242 "TTYH2/3 transport cytosolic Cl- to extracellular region" +xref: Reactome:R-HSA-2744361 "BESTs transport cytosolic Cl- to extracellular region" +is_a: GO:0022839 ! ion gated channel activity +is_a: GO:0061778 ! intracellular chloride channel activity + +[Term] +id: GO:0005230 +name: extracellular ligand-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015276 ! ligand-gated ion channel activity + +[Term] +id: GO:0005231 +name: excitatory extracellular ligand-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential." [GOC:mah, ISBN:0323037070] +xref: Reactome:R-HSA-399711 "Activation of Ca impermeable AMPA receptors" +xref: Reactome:R-HSA-399712 "Activation of Ca permeable AMPA receptors" +xref: Reactome:R-HSA-420980 "Activation of Ca permeable AMPA receptors" +xref: Reactome:R-HSA-432164 "Ca2+ influx into the post-synaptic cell" +xref: Reactome:R-HSA-438037 "Membrane depolarization upon activation of Ca impermeable AMPA receptors" +is_a: GO:0005230 ! extracellular ligand-gated ion channel activity +intersection_of: GO:0005230 ! extracellular ligand-gated ion channel activity +intersection_of: part_of GO:0060079 ! excitatory postsynaptic potential +relationship: part_of GO:0060079 ! excitatory postsynaptic potential + +[Term] +id: GO:0005234 +name: extracellularly glutamate-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane." [GOC:mtg_transport, ISBN:0815340729] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'. +synonym: "extracellular-glutamate-gated ion channel activity" EXACT [] +is_a: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity + +[Term] +id: GO:0005237 +name: inhibitory extracellular ligand-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels." [GOC:mah, ISBN:0323037070] +is_a: GO:0005230 ! extracellular ligand-gated ion channel activity + +[Term] +id: GO:0005240 +name: obsolete glycine receptor-associated protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not describe a molecular function. +synonym: "glycine receptor-associated protein" EXACT [] +is_obsolete: true +consider: GO:0005515 + +[Term] +id: GO:0005241 +name: obsolete inward rectifier channel +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "inward rectifier channel" EXACT [] +is_obsolete: true +consider: GO:0005242 + +[Term] +id: GO:0005242 +name: inward rectifier potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself." [GOC:cb, GOC:mah, PMID:14977398] +synonym: "Kir channel activity" EXACT [GOC:cb] +xref: Reactome:R-HSA-1296045 "Activation of Potassium transport channels" +xref: Reactome:R-HSA-1296046 "KCNJs transport K+ from the extracellular region to cytosol" +xref: Reactome:R-HSA-1369017 "Activation of ATP sensitive Potassium channels in muscle cells" +xref: Reactome:R-HSA-5678261 "KCNJ11:ABCC9 transports K+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5678418 "Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol" +is_a: GO:0005249 ! voltage-gated potassium channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0005243 +name: gap junction channel activity +namespace: molecular_function +alt_id: GO:0015285 +alt_id: GO:0015286 +def: "A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes." [GOC:dgh, GOC:mtg_transport, ISBN:0815340729] +synonym: "connexin" RELATED [] +synonym: "innexin" NARROW [] +synonym: "innexin channel activity" EXACT [] +synonym: "intercellular channel" BROAD [] +xref: Reactome:R-HSA-190681 "Connexin oligomerization in endoplasmic reticulum membrane" +xref: Reactome:R-HSA-375330 "Connexin 45/Connexin 36 mediated neuronal gap junction communication" +xref: Reactome:R-HSA-375339 "Pannexin 1/Pannexin2 mediated neuronal gap junction communication" +xref: Reactome:R-HSA-375340 "Connexin 62 mediated neuronal gap junction communication" +xref: Reactome:R-HSA-375342 "Connexin 36 mediated neuronal gap junction communication" +is_a: GO:0022829 ! wide pore channel activity + +[Term] +id: GO:0005244 +name: voltage-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "voltage gated ion channel activity" EXACT [] +synonym: "voltage-dependent ion channel activity" EXACT [] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0022832 ! voltage-gated channel activity + +[Term] +id: GO:0005245 +name: voltage-gated calcium channel activity +namespace: molecular_function +alt_id: GO:0010173 +alt_id: GO:0015270 +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, GOC:tb, ISBN:0815340729] +synonym: "depolarization-activated calcium channel" BROAD [] +synonym: "depolarization-activated voltage gated calcium channel activity" EXACT [] +synonym: "depolarization-activated voltage-gated calcium channel" EXACT [] +synonym: "depolarization-activated voltage-gated calcium channel activity" EXACT [] +synonym: "dihydropyridine-sensitive calcium channel activity" NARROW [] +synonym: "voltage gated calcium channel activity" EXACT [] +synonym: "voltage-dependent calcium channel activity" EXACT [] +synonym: "voltage-gated calcium ion channel activity" EXACT [] +synonym: "voltage-sensitive calcium channel" EXACT [] +xref: Reactome:R-HSA-265645 "Calcium Influx through Voltage-gated Calcium Channels" +xref: Reactome:R-HSA-5577213 "LTCC heteropentamer (open) transports Ca2+ from extracellular region to cytosol" +is_a: GO:0005262 ! calcium channel activity +is_a: GO:0022843 ! voltage-gated cation channel activity + +[Term] +id: GO:0005246 +name: calcium channel regulator activity +namespace: molecular_function +def: "Modulates the activity of a calcium channel." [GOC:mah] +is_a: GO:0099106 ! ion channel regulator activity + +[Term] +id: GO:0005247 +name: voltage-gated chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] +synonym: "voltage gated chloride channel activity" EXACT [] +synonym: "voltage-dependent chloride channel activity" EXACT [] +xref: Reactome:R-HSA-2744228 "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region" +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0008308 ! voltage-gated anion channel activity + +[Term] +id: GO:0005248 +name: voltage-gated sodium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] +synonym: "voltage gated sodium channel activity" EXACT [] +synonym: "voltage-dependent sodium channel activity" EXACT [] +synonym: "voltage-gated sodium ion channel activity" EXACT [] +synonym: "voltage-sensitive sodium channel" EXACT [] +xref: Reactome:R-HSA-5576895 "SCNAs:SNCBs transport Na+ from extracellular region to cytosol" +is_a: GO:0005272 ! sodium channel activity + +[Term] +id: GO:0005249 +name: voltage-gated potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] +synonym: "voltage gated potassium channel activity" EXACT [] +synonym: "voltage-dependent potassium channel activity" EXACT [] +synonym: "voltage-gated potassium ion channel activity" EXACT [] +synonym: "voltage-sensitive potassium channel" EXACT [] +xref: Reactome:R-HSA-1296127 "Activation of voltage gated Potassium channels" +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0022843 ! voltage-gated cation channel activity + +[Term] +id: GO:0005250 +name: A-type (transient outward) potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential." [GOC:mah, PMID:5575340] +xref: Reactome:R-HSA-5577234 "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extrqcellular region" +is_a: GO:0015271 ! outward rectifier potassium channel activity + +[Term] +id: GO:0005251 +name: delayed rectifier potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow." [GOC:mah, PMID:11343411, PMID:2462513] +xref: Reactome:R-HSA-5577050 "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region" +xref: Reactome:R-HSA-5577237 "KCNH2:KCNE transport K+ from cytosol to extracellular region" +is_a: GO:0005249 ! voltage-gated potassium channel activity + +[Term] +id: GO:0005252 +name: open rectifier potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration." [GOC:mah, PMID:8917578] +is_a: GO:0005249 ! voltage-gated potassium channel activity + +[Term] +id: GO:0005253 +name: anion channel activity +namespace: molecular_function +def: "Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +synonym: "non-selective anion channel activity" NARROW [] +xref: Reactome:R-HSA-432034 "Aquaporin-6 passively transports anions into vesicles" +xref: Reactome:R-HSA-432036 "Aquaporin-6 passively transports anions out of vesicles" +is_a: GO:0005216 ! ion channel activity +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +disjoint_from: GO:0005261 ! cation channel activity + +[Term] +id: GO:0005254 +name: chloride channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: Reactome:R-HSA-2744349 "TTYH1 transports cytosolic Cl- to extracellular region" +xref: Reactome:R-HSA-427570 "Group 3 - Selective Cl- transport" +xref: Reactome:R-HSA-975340 "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol" +xref: Reactome:R-HSA-975449 "GABRR pentamer:GABA transports extracellular Cl- to cytosol" +is_a: GO:0005253 ! anion channel activity +is_a: GO:0015108 ! chloride transmembrane transporter activity + +[Term] +id: GO:0005260 +name: intracellularly ATP-gated chloride channel activity +namespace: molecular_function +alt_id: GO:0005224 +def: "Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane." [PMID:24727426, PMID:9922375] +synonym: "ATP phosphohydrolase (channel-conductance-controlling)" EXACT [EC:5.6.1.6] +synonym: "ATP-binding and phosphorylation-dependent chloride channel activity" EXACT [] +synonym: "channel-conductance-controlling ATPase activity" EXACT [] +synonym: "cystic fibrosis transmembrane conductance regulator" NARROW [] +synonym: "cystic-fibrosis membrane-conductance-regulating protein activity" NARROW [EC:5.6.1.6] +xref: EC:5.6.1.6 +xref: MetaCyc:3.6.3.49-RXN +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity +is_a: GO:0099142 ! intracellularly ATP-gated ion channel activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14402 xsd:anyURI + +[Term] +id: GO:0005261 +name: cation channel activity +namespace: molecular_function +alt_id: GO:0015281 +alt_id: GO:0015338 +def: "Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:def, GOC:dph, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +synonym: "cation diffusion facilitator activity" EXACT [] +synonym: "non-selective cation channel activity" NARROW [] +xref: Reactome:R-HSA-1168376 "STIM1 oligomerizes" +xref: Reactome:R-HSA-1296043 "Activation of HCN channels" +xref: Reactome:R-HSA-169683 "IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol" +xref: Reactome:R-HSA-2089943 "TRPC1 translocates calcium from the extracellular region to the cytosol" +xref: Reactome:R-HSA-426223 "Cation influx mediated by TRPC3/6/7" +xref: Reactome:R-HSA-4420052 "Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT" +is_a: GO:0005216 ! ion channel activity +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity + +[Term] +id: GO:0005262 +name: calcium channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: Reactome:R-HSA-139854 "IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol" +xref: Reactome:R-HSA-139855 "P2X1-mediated entry of Ca++ from plasma" +xref: Reactome:R-HSA-210420 "Ca2+ influx through voltage gated Ca2+ channels" +xref: Reactome:R-HSA-3295579 "TRPs transport extracellular Ca2+ to cytosol" +xref: Reactome:R-HSA-5263618 "CACFD1 dimer transports Ca2+ from extracellular region to cytosol" +xref: Reactome:R-HSA-8949145 "VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space" +xref: Reactome:R-HSA-8949178 "MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix" +is_a: GO:0005261 ! cation channel activity +is_a: GO:0015085 ! calcium ion transmembrane transporter activity + +[Term] +id: GO:0005267 +name: potassium channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:BHF, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: Reactome:R-HSA-1296024 "Activation of ATP sensitive Potassium channels in neuroendocrine cells" +xref: Reactome:R-HSA-1296035 "Activation of Ca2+ activated Potassium channels with Intermeidtance conductance" +xref: Reactome:R-HSA-1296037 "Activation of Ca2+ activated Potassium channels with large conductance" +xref: Reactome:R-HSA-1296039 "Activation of Ca2+ activated Potassium channels with small conductance" +xref: Reactome:R-HSA-1296348 "Activation of TWIK-related K+ channel (TREK)" +xref: Reactome:R-HSA-1299297 "Activation of THIK" +xref: Reactome:R-HSA-1299304 "Activation of tandem pore domain in a weak inwardly rectifying K+ channels" +xref: Reactome:R-HSA-1299318 "Activation of TASK" +xref: Reactome:R-HSA-1299338 "Activation of TRESK" +xref: Reactome:R-HSA-1299359 "Activation of TALK" +xref: Reactome:R-HSA-2534365 "Slo3 Potassium Transport" +xref: Reactome:R-HSA-5578910 "KCNK dimers transport K+ from cytosol to extracellular region" +is_a: GO:0005261 ! cation channel activity +is_a: GO:0015079 ! potassium ion transmembrane transporter activity + +[Term] +id: GO:0005272 +name: sodium channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:BHF, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: Reactome:R-HSA-2730664 "UNC79:UNC80:NALCN transports cytosolic Na+ to extracellular region" +xref: Reactome:R-HSA-3295580 "TRPM4,5 transport extracellular Na+ to cytosol" +is_a: GO:0005261 ! cation channel activity +is_a: GO:0015081 ! sodium ion transmembrane transporter activity + +[Term] +id: GO:0005274 +name: allantoin:proton symporter activity +namespace: molecular_function +alt_id: GO:0015206 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.39.3.1] +synonym: "allantoin permease activity" RELATED [] +synonym: "allantoin uptake transmembrane transporter activity" NARROW [] +synonym: "allantoin/allantoate transporter" BROAD [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0015720 ! allantoin transport + +[Term] +id: GO:0005275 +name: amine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005279 +def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "amine/amide/polyamine channel activity" BROAD [] +synonym: "amine/polyamine transmembrane transporter activity" EXACT [] +synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015837 ! amine transport + +[Term] +id: GO:0005276 +name: obsolete vesicular amino acid:proton antiporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in)." [GOC:mah, Reactome:428625] +comment: The reason for obsoletion is that the cellular component does not belong is the MF according to the documentation: http://wiki.geneontology.org/index.php/Transporter_terms_standard_definitions +synonym: "hydrogen:vesicular amine antiporter activity" EXACT [] +synonym: "vesicular hydrogen:amino acid antiporter activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005277 +name: acetylcholine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] +xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicle" +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:1901375 ! acetate ester transmembrane transporter activity + +[Term] +id: GO:0005278 +name: acetylcholine:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out)." [TC:2.A.1.2.13] +synonym: "acetylcholine:hydrogen antiporter activity" EXACT [] +is_a: GO:0005277 ! acetylcholine transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0005280 +name: amino acid:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in)." [GOC:ai] +synonym: "cation/amino acid symporter" BROAD [] +synonym: "hydrogen:amino acid symporter activity" EXACT [] +xref: Reactome:R-HSA-8875623 "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix" +is_a: GO:0005416 ! amino acid:cation symporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0005281 +name: obsolete general amino acid permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "general amino acid permease activity" EXACT [] +synonym: "general amino acid transporter" BROAD [] +is_obsolete: true +replaced_by: GO:0015171 + +[Term] +id: GO:0005283 +name: amino acid:sodium symporter activity +namespace: molecular_function +alt_id: GO:0005284 +alt_id: GO:0005285 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in)." [GOC:ai] +synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] +synonym: "insulin-activated sodium/amino acid transporter activity" NARROW [] +synonym: "insulin-activated sodium:amino acid symporter activity" NARROW [] +synonym: "insulin-activated sodium:amino acid transporter activity" NARROW [] +synonym: "isoleucine/valine:sodium symporter activity" NARROW [] +synonym: "sodium/amino acid transporter activity" BROAD [] +synonym: "sodium/excitatory amino acid cotransporter activity" BROAD [] +synonym: "sodium/excitatory amino acid symporter activity" EXACT [] +synonym: "sodium:amino acid symporter activity" EXACT [] +synonym: "sodium:amino acid transporter activity" BROAD [] +synonym: "threonine/serine:sodium symporter activity" NARROW [] +is_a: GO:0005343 ! organic acid:sodium symporter activity +is_a: GO:0005416 ! amino acid:cation symporter activity + +[Term] +id: GO:0005287 +name: high-affinity basic amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity basic amino acid transmembrane transporter activity" EXACT [] +synonym: "high-affinity basic amino acid transporter activity" BROAD [] +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity + +[Term] +id: GO:0005289 +name: high-affinity arginine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity arginine transmembrane transporter activity" EXACT [] +synonym: "high-affinity arginine transporter activity" BROAD [] +is_a: GO:0005287 ! high-affinity basic amino acid transmembrane transporter activity +is_a: GO:0015181 ! arginine transmembrane transporter activity + +[Term] +id: GO:0005290 +name: L-histidine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] +synonym: "L-histidine transporter activity" BROAD [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +relationship: part_of GO:0089709 ! L-histidine transmembrane transport + +[Term] +id: GO:0005291 +name: high-affinity L-histidine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity histidine permease activity" RELATED [] +synonym: "high affinity L-histidine transmembrane transporter activity" EXACT [] +is_a: GO:0005287 ! high-affinity basic amino acid transmembrane transporter activity +is_a: GO:0005290 ! L-histidine transmembrane transporter activity + +[Term] +id: GO:0005292 +name: high-affinity lysine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity lysine transmembrane transporter activity" EXACT [] +synonym: "high affinity lysine transporter activity" BROAD [] +is_a: GO:0005287 ! high-affinity basic amino acid transmembrane transporter activity +is_a: GO:0015189 ! L-lysine transmembrane transporter activity + +[Term] +id: GO:0005294 +name: neutral L-amino acid secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "neutral L-amino acid porter activity" RELATED [] +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0005295 +name: neutral amino acid:sodium symporter activity +namespace: molecular_function +alt_id: GO:0005282 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in)." [TC:2.A.23.3.1] +synonym: "neutral amino acid-sodium cotransporter" BROAD [] +synonym: "sodium/neutral amino acid transporter" BROAD [] +is_a: GO:0005283 ! amino acid:sodium symporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity + +[Term] +id: GO:0005297 +name: proline:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in)." [GOC:ai] +synonym: "hydrogen/proline transporter" BROAD [] +is_a: GO:0005280 ! amino acid:proton symporter activity + +[Term] +id: GO:0005298 +name: proline:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in)." [TC:2.A.22.2.1] +synonym: "sodium/proline symporter activity" EXACT [] +xref: Reactome:R-HSA-444100 "PROT mediates L-proline uptake" +xref: RHEA:28967 +is_a: GO:0005283 ! amino acid:sodium symporter activity + +[Term] +id: GO:0005300 +name: high-affinity tryptophan transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport, ISBN:0815340729] +synonym: "high-affinity tryptophan transporter activity" BROAD [] +is_a: GO:0015196 ! L-tryptophan transmembrane transporter activity + +[Term] +id: GO:0005301 +name: obsolete valine/tyrosine/tryptophan permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "hydrogen/valine-tyrosine-tryptophan transporter" EXACT [] +synonym: "valine/tyrosine/tryptophan permease activity" EXACT [] +is_obsolete: true +consider: GO:0005302 +consider: GO:0005304 +consider: GO:0015196 +consider: GO:0022857 + +[Term] +id: GO:0005302 +name: L-tyrosine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015508 +def: "Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-tyrosine permease activity" EXACT [] +synonym: "L-tyrosine transporter activity" BROAD [] +synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015828 ! tyrosine transport + +[Term] +id: GO:0005304 +name: L-valine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "isoleucine/valine:sodium symporter activity" NARROW [] +synonym: "L-valine transporter activity" BROAD [] +synonym: "leucine/isoleucine/valine porter activity" NARROW [] +synonym: "leucine/valine/isoleucine permease activity" NARROW [] +synonym: "valine/tyrosine/tryptophan permease activity" NARROW [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015658 ! branched-chain amino acid transmembrane transporter activity +relationship: part_of GO:1903785 ! L-valine transmembrane transport + +[Term] +id: GO:0005307 +name: choline:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in)." [TC:2.A.22.3.5] +synonym: "sodium/choline symporter activity" EXACT [] +is_a: GO:0005328 ! neurotransmitter:sodium symporter activity +is_a: GO:0015220 ! choline transmembrane transporter activity + +[Term] +id: GO:0005308 +name: creatine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle." [GOC:ai] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:0015881 ! creatine transmembrane transport + +[Term] +id: GO:0005309 +name: creatine:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in)." [TC:2.A.22.3.4] +synonym: "sodium/chloride-dependent creatine transporter" BROAD [] +xref: Reactome:R-HSA-200396 "Creatine transport across the plasma membrane" +is_a: GO:0005308 ! creatine transmembrane transporter activity +is_a: GO:0140161 ! monocarboxylate:sodium symporter activity + +[Term] +id: GO:0005310 +name: dicarboxylic acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005312 +alt_id: GO:0015365 +def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] +synonym: "dicarboxylate carrier" NARROW [] +synonym: "dicarboxylic acid permease activity" RELATED [] +synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] +xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" +xref: Reactome:R-HSA-372843 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]" +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +relationship: part_of GO:0006835 ! dicarboxylic acid transport + +[Term] +id: GO:0005311 +name: obsolete sodium:dicarboxylate/tricarboxylate symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in)." [TC:2.A.47.1.5] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "sodium:dicarboxylate/tricarboxylate cotransporter activity" BROAD [] +synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" EXACT [] +is_obsolete: true +consider: GO:0005310 +consider: GO:0005343 +consider: GO:0015142 + +[Term] +id: GO:0005313 +name: L-glutamate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "glutamate/aspartate porter activity" NARROW [] +synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] +synonym: "L-glutamate transporter activity" BROAD [] +xref: Reactome:R-HSA-210444 "L-Glutamate loading of synaptic vesicle" +xref: Reactome:R-HSA-428052 "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+" +xref: Reactome:R-HSA-5624256 "Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+" +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015172 ! acidic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015813 ! L-glutamate transmembrane transport + +[Term] +id: GO:0005314 +name: high-affinity glutamate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.3.10.5] +synonym: "high-affinity glutamate transporter activity" BROAD [] +xref: Reactome:R-HSA-210404 "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+" +xref: Reactome:R-HSA-428015 "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5625015 "Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5625029 "SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol" +is_a: GO:0005313 ! L-glutamate transmembrane transporter activity +is_a: GO:0005328 ! neurotransmitter:sodium symporter activity +is_a: GO:0015501 ! glutamate:sodium symporter activity + +[Term] +id: GO:0005315 +name: inorganic phosphate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005317 +def: "Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity + +[Term] +id: GO:0005316 +name: high-affinity inorganic phosphate:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.20.2.2] +synonym: "high affinity inorganic phosphate:sodium symporter activity" EXACT [] +synonym: "sodium/phosphate cotransporter activity" BROAD [] +is_a: GO:0005436 ! sodium:phosphate symporter activity + +[Term] +id: GO:0005318 +name: obsolete phosphate:hydrogen symporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +synonym: "phosphate:hydrogen symporter" EXACT [] +synonym: "phosphate:proton symporter activity" EXACT [] +is_obsolete: true +consider: GO:0015317 + +[Term] +id: GO:0005319 +name: lipid transporter activity +namespace: molecular_function +def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai] +synonym: "apolipoprotein" RELATED [] +synonym: "lipophorin" NARROW [] +xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux" +xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx" +xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex" +xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region" +xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region" +xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" +xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body" +xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" +xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane" +xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" +is_a: GO:0005215 ! transporter activity +relationship: part_of GO:0006869 ! lipid transport + +[Term] +id: GO:0005320 +name: obsolete apolipoprotein +namespace: molecular_function +alt_id: GO:0015907 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "apolipoprotein" EXACT [] +is_obsolete: true +consider: GO:0005319 + +[Term] +id: GO:0005321 +name: obsolete high-density lipoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "HDL" EXACT [] +synonym: "high-density lipoprotein" EXACT [] +is_obsolete: true +replaced_by: GO:0005319 + +[Term] +id: GO:0005322 +name: obsolete low-density lipoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "LDL" EXACT [] +synonym: "low-density lipoprotein" EXACT [] +is_obsolete: true +replaced_by: GO:0005319 + +[Term] +id: GO:0005323 +name: obsolete very-low-density lipoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "very-low-density lipoprotein" EXACT [] +synonym: "VLDL" EXACT [] +is_obsolete: true +replaced_by: GO:0005319 + +[Term] +id: GO:0005324 +name: long-chain fatty acid transporter activity +namespace: molecular_function +alt_id: GO:0005325 +alt_id: GO:0008562 +def: "Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [ISBN:0198506732, RHEA:15181] +synonym: "ATP phosphohydrolase (fatty-acyl-CoA-transporting)" EXACT [EC:7.6.2.4] +synonym: "fatty-acyl-CoA-transporting ATPase" BROAD [] +synonym: "peroxisomal fatty acyl CoA transporter activity" NARROW [] +synonym: "peroxisomal fatty-acyl-CoA transmembrane transporter activity" NARROW [] +synonym: "peroxisomal fatty-acyl-CoA transporter activity" NARROW [] +synonym: "plasma membrane long-chain fatty acid transporter" NARROW [] +xref: EC:7.6.2.4 +xref: Reactome:R-HSA-2046087 "Translocation of tetracosahexaenoyl-CoA to peroxisomes" +xref: Reactome:R-HSA-2046093 "Translocation of tetracosapentaenoyl-CoA to peroxisomes" +xref: Reactome:R-HSA-382575 "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix" +xref: Reactome:R-HSA-390393 "Peroxisomal uptake of very long-chain fatty acyl CoA" +xref: Reactome:R-HSA-434381 "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol" +xref: Reactome:R-HSA-5684043 "Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix" +xref: RHEA:15181 +is_a: GO:0005319 ! lipid transporter activity +relationship: part_of GO:0015909 ! long-chain fatty acid transport + +[Term] +id: GO:0005326 +name: neurotransmitter transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732] +synonym: "neurotransmitter transmembrane transporter activity" EXACT [GOC:mah] +synonym: "neurotransmitter transporter activity" RELATED [] +xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline" +xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft" +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0006836 ! neurotransmitter transport + +[Term] +id: GO:0005328 +name: neurotransmitter:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in)." [TC:2.A.22.-.-] +synonym: "sodium/neurotransmitter symporter activity" EXACT [] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0005330 +name: dopamine:sodium symporter activity +namespace: molecular_function +alt_id: GO:0005329 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in)." [PMID:21752877, PMID:22519513, TC:2.A.22.1.3] +synonym: "dopamine transmembrane transporter activity" EXACT [] +synonym: "dopamine:sodium:chloride symporter activity" EXACT [] +synonym: "sodium/dopamine symporter activity" EXACT [] +is_a: GO:0008504 ! monoamine transmembrane transporter activity +is_a: GO:0015378 ! sodium:chloride symporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0090494 ! dopamine uptake +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16054 xsd:anyURI + +[Term] +id: GO:0005332 +name: gamma-aminobutyric acid:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in)." [TC:2.A.22.3.2] +comment: See also the molecular function term 'neurotransmitter:sodium symporter activity ; GO:0005328'. +synonym: "4-aminobutanoate:sodium symporter activity" EXACT [] +synonym: "4-aminobutyrate:sodium symporter activity" EXACT [] +synonym: "betaine/GABA:sodium symporter activity" EXACT [] +synonym: "GABA:sodium symporter activity" EXACT [] +synonym: "sodium/chloride-dependent GABA transporter activity" BROAD [] +xref: Reactome:R-HSA-444007 "GAT1-3 mediate Na+/Cl- dependent GABA transport" +is_a: GO:0005283 ! amino acid:sodium symporter activity +is_a: GO:0005328 ! neurotransmitter:sodium symporter activity +is_a: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity +is_a: GO:0140161 ! monocarboxylate:sodium symporter activity + +[Term] +id: GO:0005334 +name: norepinephrine:sodium symporter activity +namespace: molecular_function +alt_id: GO:0005333 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in)." [PMID:21752877, PMID:22519513, TC:2.A.22.1.2] +synonym: "levarterenol transporter activity" EXACT [] +synonym: "noradrenaline transporter activity" EXACT [] +synonym: "norepinephrine transmembrane transporter activity" EXACT [] +synonym: "norepinephrine:sodium symporter activity" EXACT [] +synonym: "norepinephrine:sodium:chloride symporter activity" EXACT [] +synonym: "sodium/norepinephrine symporter activity" EXACT [] +xref: Reactome:R-HSA-443997 "SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5659764 "Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol" +xref: Wikipedia:Norepinephrine_transporter +is_a: GO:0008504 ! monoamine transmembrane transporter activity +is_a: GO:0015378 ! sodium:chloride symporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0051620 ! norepinephrine uptake + +[Term] +id: GO:0005335 +name: serotonin:sodium symporter activity +namespace: molecular_function +alt_id: GO:0005336 +alt_id: GO:0015222 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in)." [PMID:21752877, PMID:22519513, TC:2.A.22.1.1] +synonym: "serotonin transmembrane transporter activity" EXACT [] +synonym: "serotonin:sodium:chloride symporter activity" EXACT [] +synonym: "sodium/serotonin symporter activity" EXACT [] +xref: Reactome:R-HSA-444008 "SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol" +is_a: GO:0005328 ! neurotransmitter:sodium symporter activity +is_a: GO:0008504 ! monoamine transmembrane transporter activity +is_a: GO:0015378 ! sodium:chloride symporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0051610 ! serotonin uptake + +[Term] +id: GO:0005337 +name: nucleoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other." [GOC:ai] +synonym: "intracellular nucleoside transmembrane transporter activity" NARROW [] +xref: Reactome:R-HSA-109527 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2" +xref: Reactome:R-HSA-109529 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2" +xref: Reactome:R-HSA-109534 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1" +xref: Reactome:R-HSA-109536 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1" +xref: Reactome:R-HSA-5628807 "Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-727740 "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4" +xref: Reactome:R-HSA-727749 "SLC29A3 transports nucleosides from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-727767 "SLC29A3 transports nucleosides from cytosol to lysosomal lumen" +xref: Reactome:R-HSA-727768 "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4" +is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:1901642 ! nucleoside transmembrane transport + +[Term] +id: GO:0005338 +name: nucleotide-sugar transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005339 +def: "Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, PMID:15034926] +xref: Reactome:R-HSA-744230 "SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP" +xref: Reactome:R-HSA-744231 "SLC35D2 exchanges UDP-sugars for UMP" +is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity + +[Term] +id: GO:0005340 +name: nucleotide-sulfate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005341 +def: "Enables the transfer of nucleotide-sulfate from one side of a membrane to the other." [GOC:mtg_transport] +synonym: "nucleotide-sulphate transporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015116 ! sulfate transmembrane transporter activity +is_a: GO:0015215 ! nucleotide transmembrane transporter activity + +[Term] +id: GO:0005342 +name: organic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1903825 ! organic acid transmembrane transport + +[Term] +id: GO:0005343 +name: organic acid:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in)." [TC:2.A.28.1.1] +synonym: "sodium/chloride-dependent organic acid cotransporter activity" RELATED [] +synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] +xref: Reactome:R-HSA-8876312 "SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol" +is_a: GO:0005342 ! organic acid transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0005344 +name: oxygen carrier activity +namespace: molecular_function +alt_id: GO:0015033 +def: "Enables the directed movement of oxygen into, out of or within a cell, or between cells." [GOC:ai] +synonym: "globin" NARROW [] +synonym: "hemerythrin" NARROW [] +synonym: "hemocyanin" NARROW [] +synonym: "oxygen-carrying" NARROW [] +is_a: GO:0005215 ! transporter activity +relationship: part_of GO:0015671 ! oxygen transport + +[Term] +id: GO:0005345 +name: purine nucleobase transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other." [ISBN:0198506732] +synonym: "purine base transmembrane transporter activity" EXACT [GOC:go_curators] +synonym: "purine transmembrane transporter activity" RELATED [] +is_a: GO:0015205 ! nucleobase transmembrane transporter activity +relationship: part_of GO:1904823 ! purine nucleobase transmembrane transport + +[Term] +id: GO:0005346 +name: purine ribonucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015216 ! purine nucleotide transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity + +[Term] +id: GO:0005347 +name: ATP transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005348 +def: "Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +relationship: part_of GO:0015867 ! ATP transport + +[Term] +id: GO:0005350 +name: pyrimidine nucleobase transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other." [GOC:ai] +synonym: "pyrimidine base transmembrane transporter activity" EXACT [GOC:go_curators] +synonym: "pyrimidine transmembrane transporter activity" RELATED [] +is_a: GO:0015205 ! nucleobase transmembrane transporter activity +relationship: part_of GO:0015855 ! pyrimidine nucleobase transport +relationship: part_of GO:0072531 ! pyrimidine-containing compound transmembrane transport + +[Term] +id: GO:0005351 +name: carbohydrate:proton symporter activity +namespace: molecular_function +alt_id: GO:0005403 +alt_id: GO:0015542 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in)." [TC:2.A.1.1] +synonym: "cation/sugar symporter activity" NARROW [] +synonym: "hydrogen:sugar symporter activity" NARROW [] +synonym: "hydrogen:sugar transporter activity" BROAD [] +synonym: "lactose/glucose efflux transporter activity" NARROW [] +synonym: "proton:sugar symporter activity" EXACT [] +synonym: "sugar efflux transmembrane transporter activity" NARROW [PMID:20971900] +synonym: "sugar porter activity" NARROW [] +synonym: "sugar transporter" BROAD [] +synonym: "sugar:hydrogen ion symporter activity" NARROW [] +synonym: "sugar:hydrogen symporter activity" EXACT [] +synonym: "sugar:proton symporter activity" NARROW [] +xref: TC:2.A.1.1 +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0005352 +name: alpha-glucoside:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose." [TC:2.A.1.1.11] +synonym: "alpha-glucoside:hydrogen symporter activity" EXACT [] +synonym: "general alpha-glucoside transporter activity" BROAD [] +synonym: "general alpha-glucoside:hydrogen symporter activity" EXACT [] +synonym: "general alpha-glucoside:proton symporter activity" EXACT [] +is_a: GO:0015151 ! alpha-glucoside transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0005353 +name: fructose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015585 +alt_id: GO:0019192 +def: "Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "fructose permease activity" EXACT [] +synonym: "fructose porter activity" EXACT [] +xref: Reactome:R-HSA-189222 "SLC2A5 transports fructose from extracellular region to cytosol" +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015755 ! fructose transmembrane transport + +[Term] +id: GO:0005354 +name: galactose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015757 ! galactose transmembrane transport + +[Term] +id: GO:0005355 +name: glucose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015579 +def: "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] +synonym: "glucose permease activity" EXACT [] +synonym: "lactose/glucose efflux transporter activity" NARROW [] +xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" +xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:1904659 ! glucose transmembrane transport + +[Term] +id: GO:0005356 +name: glucose:proton symporter activity +namespace: molecular_function +alt_id: GO:0005361 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] +synonym: "hydrogen:glucose symporter activity" EXACT [] +synonym: "hydrogen:glucose transporter activity" RELATED [] +synonym: "transepithelial hydrogen/glucose transporter activity" RELATED [] +synonym: "transepithelial hydrogen:glucose symporter activity" NARROW [] +synonym: "transepithelial hydrogen:glucose transporter activity" RELATED [] +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0009679 ! hexose:proton symporter activity + +[Term] +id: GO:0005357 +name: obsolete constitutive glucose:proton symporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] +comment: The reason for obsoletion is that the constitutive aspect of the transporter is unlikely to be an aspect of the activity, but instead it probably relates to the expression level of the transporter. +synonym: "constitutive hydrogen/glucose transporter activity" BROAD [] +synonym: "constitutive hydrogen:glucose symporter activity" EXACT [] +synonym: "constitutive hydrogen:glucose transporter activity" BROAD [] +is_obsolete: true + +[Term] +id: GO:0005358 +name: high-affinity glucose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high-affinity hydrogen/glucose transporter activity" BROAD [] +synonym: "high-affinity hydrogen:glucose symporter activity" EXACT [] +synonym: "high-affinity hydrogen:glucose transporter activity" BROAD [] +is_a: GO:0005356 ! glucose:proton symporter activity + +[Term] +id: GO:0005359 +name: low-affinity glucose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] +synonym: "low-affinity hydrogen/glucose transporter activity" BROAD [] +synonym: "low-affinity hydrogen:glucose symporter activity" EXACT [] +synonym: "low-affinity hydrogen:glucose transporter activity" BROAD [] +is_a: GO:0005356 ! glucose:proton symporter activity + +[Term] +id: GO:0005360 +name: insulin-responsive glucose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] +synonym: "insulin-responsive hydrogen:glucose symporter activity" EXACT [] +synonym: "insulin-responsive hydrogen:glucose transporter activity" RELATED [] +synonym: "transepithelial hydrogen/glucose transporter activity" RELATED [] +is_a: GO:0005356 ! glucose:proton symporter activity + +[Term] +id: GO:0005362 +name: low-affinity glucose:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.21.3.-] +synonym: "low-affinity glucose-sodium cotransporter activity" BROAD [] +xref: Reactome:R-HSA-429567 "Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4" +is_a: GO:0005412 ! glucose:sodium symporter activity + +[Term] +id: GO:0005363 +name: maltose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015581 +def: "Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "maltose porter activity" EXACT [] +xref: RHEA:33171 +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0015768 ! maltose transport + +[Term] +id: GO:0005364 +name: maltose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in)." [TC:2.A.1.1.10] +synonym: "hydrogen/maltose transporter activity" BROAD [] +synonym: "maltose permease" BROAD [] +synonym: "maltose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0005363 ! maltose transmembrane transporter activity + +[Term] +id: GO:0005365 +name: myo-inositol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms." [GOC:ai] +synonym: "vitamin Bh transporter activity" EXACT [] +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015798 ! myo-inositol transport + +[Term] +id: GO:0005366 +name: myo-inositol:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in)." [TC:2.A.1.1.8] +synonym: "hydrogen/myo-inositol transporter activity" BROAD [] +synonym: "myo-inositol:hydrogen symporter activity" EXACT [] +xref: Reactome:R-HSA-429101 "HMIT co-transports myo-inositol with a proton" +is_a: GO:0005365 ! myo-inositol transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0005367 +name: myo-inositol:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in)." [TC:2.A.21.4.-] +synonym: "myo-inositol-sodium cotransporter activity" BROAD [] +xref: Reactome:R-HSA-429663 "SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol" +is_a: GO:0005365 ! myo-inositol transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0005368 +name: taurine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats." [GOC:ai] +xref: RHEA:14613 +is_a: GO:0042959 ! alkanesulfonate transmembrane transporter activity +relationship: part_of GO:0015734 ! taurine transport + +[Term] +id: GO:0005369 +name: taurine:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in)." [TC:2.A.22.3.3] +synonym: "sodium/chloride-dependent taurine transporter" BROAD [] +is_a: GO:0005343 ! organic acid:sodium symporter activity +is_a: GO:0005368 ! taurine transmembrane transporter activity + +[Term] +id: GO:0005371 +name: tricarboxylate secondary active transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005370 +def: "Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport, ISBN:0815340729] +synonym: "tricarboxylate carrier activity" EXACT [] +is_a: GO:0015142 ! tricarboxylic acid transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0005372 +name: water transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of water (H2O) from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0006833 ! water transport + +[Term] +id: GO:0005373 +name: obsolete heavy metal ion porter activity +namespace: molecular_function +def: "OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "heavy metal ion porter activity" EXACT [] +synonym: "metal ion transporter" BROAD [] +is_obsolete: true +consider: GO:0015291 +consider: GO:0046873 + +[Term] +id: GO:0005375 +name: copper ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005378 +alt_id: GO:0005379 +alt_id: GO:0005380 +alt_id: GO:0015088 +def: "Enables the transfer of copper (Cu) ions from one side of a membrane to the other." [GOC:ai] +synonym: "copper uptake transmembrane transporter activity" RELATED [] +synonym: "intracellular copper ion transporter" NARROW [] +synonym: "plasma membrane copper transporter" NARROW [] +xref: Reactome:R-HSA-437300 "SLC31A1 transports Cu2+ from extracellular region to cytosol" +xref: RHEA:28703 +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0035434 ! copper ion transmembrane transport + +[Term] +id: GO:0005376 +name: obsolete plasma membrane copper transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "plasma membrane copper transporter" EXACT [] +is_obsolete: true +consider: GO:0005375 +consider: GO:0005886 + +[Term] +id: GO:0005377 +name: obsolete intracellular copper ion transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "intracellular copper ion transporter" EXACT [] +synonym: "intracellular copper transporter" EXACT [] +is_obsolete: true +consider: GO:0005375 +consider: GO:0005622 + +[Term] +id: GO:0005381 +name: iron ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005382 +alt_id: GO:0016033 +alt_id: GO:0097689 +def: "Enables the transfer of iron (Fe) ions from one side of a membrane to the other." [GOC:ai] +comment: An example of this is mouse ferroportin (UniProtKB:Q9JHI9), which transports iron out of the cell. +synonym: "iron cation channel activity" EXACT [] +synonym: "iron channel activity" EXACT [] +synonym: "iron transporter activity" EXACT [] +synonym: "multicopper ferroxidase iron transport mediator activity" RELATED [] +synonym: "transmembrane iron ion permease activity" EXACT [] +synonym: "transmembrane iron permease activity" EXACT [] +synonym: "zinc, iron permease activity" RELATED [] +xref: Reactome:R-HSA-435349 "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5623558 "Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5655733 "Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region" +xref: Reactome:R-HSA-904830 "SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region" +xref: Reactome:R-HSA-917936 "MCOLN1 transports Fe2+ from endosome lumen to cytosol" +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0034755 ! iron ion transmembrane transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17162 xsd:anyURI + +[Term] +id: GO:0005384 +name: manganese ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of manganese (Mn) ions from one side of a membrane to the other." [GOC:dgf] +xref: Reactome:R-HSA-8959798 "SLC30A10 transports Mn2+ from cytosol to extracellular region" +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0071421 ! manganese ion transmembrane transport + +[Term] +id: GO:0005385 +name: zinc ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of zinc (Zn) ions from one side of a membrane to the other." [GOC:dgf] +synonym: "cobalt, zinc uptake permease activity" RELATED [] +synonym: "zinc, cadmium uptake permease activity" RELATED [] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] +synonym: "zinc, iron permease activity" NARROW [] +xref: Reactome:R-HSA-435366 "ZnT1 mediates the efflux of zinc from the cell" +xref: Reactome:R-HSA-435375 "ZnT2 facilitates zinc vesicular sequestration" +xref: Reactome:R-HSA-437084 "ZnT3 transports zinc into synaptic vesicles" +xref: Reactome:R-HSA-437085 "ZnT5 transports zinc into secretory granules in pancreatic beta cells" +xref: Reactome:R-HSA-437129 "ZnT7 transports zinc into the golgi apparatus" +xref: Reactome:R-HSA-437136 "SLC30A8 transports Zn2+ from cytosol to secretory granule" +xref: Reactome:R-HSA-437139 "ZnT6 transports zinc into the golgi apparatus" +xref: Reactome:R-HSA-442317 "ZIP6 and ZIP14 mediate zinc influx into cells" +xref: Reactome:R-HSA-442345 "hZIP10 mediates zinc influx into cells" +xref: Reactome:R-HSA-442387 "ZIP8 mediates zinc influx into cells" +xref: Reactome:R-HSA-442393 "ZIP7 mediates zinc efflux from the endoplasmic reticulum" +xref: Reactome:R-HSA-442405 "hZIP5 mediates zinc uptake by cells" +xref: Reactome:R-HSA-442422 "SLC39A1-4 transports Zn2+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5654125 "Defective SLC39A4 does not transport Zn2+ from extracellular region to cytosol" +xref: RHEA:29351 +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +is_a: GO:0072509 ! divalent inorganic cation transmembrane transporter activity +relationship: part_of GO:0071577 ! zinc ion transmembrane transport + +[Term] +id: GO:0005388 +name: calcium transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans)." [EC:7.2.2.10] +synonym: "ATP-dependent calcium transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled calcium transmembrane transporter activity" RELATED [] +synonym: "Ca(2+)-transporting ATPase activity" EXACT [EC:7.2.2.10] +synonym: "Ca2+-transporting ATPase activity" EXACT [EC:7.2.2.10] +synonym: "calcium efflux ATPase" NARROW [] +synonym: "calcium pump" BROAD [] +synonym: "calcium transporting ATPase activity" EXACT [] +synonym: "calcium-translocating P-type ATPase activity" NARROW [EC:7.2.2.10] +synonym: "calcium-transporting ATPase activity" EXACT [] +synonym: "sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [] +xref: EC:7.2.2.10 +xref: MetaCyc:3.6.3.8-RXN +xref: Reactome:R-HSA-418309 "ATP2B1-4 transport cytosolic Ca2+ to extracellular region" +xref: Reactome:R-HSA-418365 "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen" +xref: Reactome:R-HSA-427910 "ATP2A1-3 transport Ca2+ from cytosol to ER lumen" +xref: Reactome:R-HSA-936883 "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen" +xref: RHEA:18105 +is_a: GO:0015085 ! calcium ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0005391 +name: sodium:potassium-exchanging ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in)." [EC:7.2.2.13] +synonym: "Na(+)/K(+)-ATPase activity" EXACT [EC:7.2.2.13] +synonym: "Na(+)/K(+)-exchanging ATPase activity" EXACT [EC:7.2.2.13] +synonym: "Na+,K+-ATPase activity" EXACT [EC:7.2.2.13] +synonym: "Na+/K+-ATPase activity" EXACT [EC:7.2.2.13] +synonym: "Na+/K+-exchanging ATPase activity" EXACT [EC:7.2.2.13] +synonym: "Na,K-activated ATPase activity" EXACT [EC:7.2.2.13] +synonym: "P-type sodium:potassium-exchanging ATPase activity" RELATED [Wikipedia:ATPase\,_Na%2B/K%2B_transporting\,_alpha_1] +synonym: "sodium pump" BROAD [EC:7.2.2.13] +synonym: "sodium/potassium-exchanging ATPase activity" EXACT [] +synonym: "sodium/potassium-transporting ATPase activity" EXACT [] +synonym: "sodium:potassium exchanging ATPase activity" EXACT [] +xref: EC:7.2.2.13 +xref: MetaCyc:3.6.3.9-RXN +xref: Reactome:R-HSA-936897 "ATP1A:ATP1B:FXYD exchanges Na+ for K+" +xref: RHEA:18353 +is_a: GO:0008554 ! sodium transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0008556 ! potassium transmembrane transporter activity, phosphorylative mechanism +relationship: part_of GO:0010248 ! establishment or maintenance of transmembrane electrochemical gradient + +[Term] +id: GO:0005395 +name: obsolete eye pigment precursor transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out)." [TC:3.A.1.204.1] +comment: This term has been obsoleted because eye pigment precursors are nucleotides and amino acids, and there are terms to annotate these functions. +xref: Reactome:R-HSA-1467466 "ABCA4 mediates atRAL transport" +xref: Reactome:R-HSA-2466749 "ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol" +xref: Reactome:R-HSA-2466802 "Defective ABCA4 does not transport NRPE from disc membranes" +is_obsolete: true + +[Term] +id: GO:0005396 +name: obsolete transmembrane conductance regulator activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because its meaning was ambiguous, it was undefined and its position in the tree wrong. +synonym: "transmembrane conductance regulator activity" EXACT [] +is_obsolete: true +consider: GO:0043267 + +[Term] +id: GO:0005400 +name: obsolete peroxisomal membrane transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "peroxisomal membrane transporter" EXACT [] +is_obsolete: true +consider: GO:0005215 +consider: GO:0005777 + +[Term] +id: GO:0005402 +name: carbohydrate:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in)." [GOC:ai] +synonym: "cation/sugar symporter activity" EXACT [] +synonym: "cation:sugar symporter activity" EXACT [] +synonym: "sugar:cation symporter activity" NARROW [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0005412 +name: glucose:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in)." [TC:2.A.21.3.-] +synonym: "sodium/glucose symporter activity" EXACT [] +xref: Reactome:R-HSA-189208 "SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol" +xref: Reactome:R-HSA-429613 "SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+" +xref: Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol" +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0005415 +name: nucleoside:sodium symporter activity +namespace: molecular_function +alt_id: GO:0008522 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in)." [GOC:ai] +synonym: "nucleoside-sodium cotransporter activity" BROAD [] +synonym: "sodium-dependent nucleoside transporter activity" BROAD [] +xref: Reactome:R-HSA-109530 "Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1" +xref: Reactome:R-HSA-109538 "Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3" +xref: Reactome:R-HSA-109539 "Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2" +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0005416 +name: amino acid:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in)." [GOC:ai] +synonym: "cation/amino acid symporter activity" EXACT [] +synonym: "cation:amino acid symporter activity" EXACT [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0005427 +name: proton-dependent oligopeptide secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement." [GOC:mtg_transport, OMIM:600544] +synonym: "hydrogen/oligopeptide symporter" RELATED [] +synonym: "proton-dependent oligopeptide transporter activity" EXACT [] +is_a: GO:0015322 ! secondary active oligopeptide transmembrane transporter activity + +[Term] +id: GO:0005429 +name: obsolete chromaffin granule amine transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of amines across chromaffin granule membranes." [GOC:mah] +comment: The term was obsoleted because its intended usage was unclear: chromaffin granules are dense core secretory vesicles (PMID:20853344) so whatever they transport must be by secretion. +is_obsolete: true + +[Term] +id: GO:0005430 +name: obsolete synaptic vesicle amine transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of amines across synaptic vesicle membranes." [GOC:ai] +comment: The class was obsoleted because the cellular location of a function should not be part of the class label. +is_obsolete: true +consider: GO:0005275 + +[Term] +id: GO:0005432 +name: calcium:sodium antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in)." [GOC:curators, PMID:16371597] +synonym: "mitochondrial sodium/calcium ion exchange" RELATED [] +synonym: "sodium/calcium exchanger" EXACT [] +synonym: "sodium:calcium exchange" RELATED [] +xref: Reactome:R-HSA-425661 "SLC8A1,2,3 exchange 3Na+ for Ca2+" +xref: Reactome:R-HSA-8949688 "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)" +xref: Reactome:R-HSA-8949703 "SLC8A3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space)" +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0015368 ! calcium:cation antiporter activity + +[Term] +id: GO:0005436 +name: sodium:phosphate symporter activity +namespace: molecular_function +alt_id: GO:0015321 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in)." [GOC:ai] +synonym: "sodium-dependent phosphate transmembrane transporter activity" RELATED [] +synonym: "sodium/phosphate symporter activity" EXACT [] +xref: Reactome:R-HSA-2872498 "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol" +is_a: GO:0015370 ! solute:sodium symporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18577 xsd:anyURI + +[Term] +id: GO:0005451 +name: monovalent cation:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out)." [GOC:ai] +synonym: "monovalent cation:hydrogen antiporter activity" EXACT [] +xref: Reactome:R-HSA-2889070 "SLC9B2 exchanges Na+, Li+ for H+" +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0005452 +name: inorganic anion exchanger activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out)." [GOC:mah] +xref: Reactome:R-HSA-1237038 "SLC4A1 exchanges cytosolic HCO3- for extracellular Cl-" +xref: Reactome:R-HSA-1247665 "Band 3 Anion Exchanger (AE1, SLC4A1) exchanges cytosolic chloride for extracellular bicarbonate" +xref: Reactome:R-HSA-425482 "SLC4A1,2,3 exchanges HCO3- for Cl-" +xref: Reactome:R-HSA-425577 "Na+-driven Cl-/HCO3- exchanger transport" +xref: Reactome:R-HSA-427666 "SLC26A3,6 exchange Cl- for HCO3-" +xref: Reactome:R-HSA-5627737 "SLC26A3 does not exchange Cl- for HCO3-" +xref: Reactome:R-HSA-5656248 "Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes)" +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0005456 +name: CMP-N-acetylneuraminate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "CMP-sialic acid transmembrane transporter activity" BROAD [] +xref: Reactome:R-HSA-5651942 "Defective SLC35A1 does not exchange CMP-Neu5Ac for CMP" +xref: Reactome:R-HSA-727807 "SLC35A1 exchanges CMP-Neu5Ac for CMP" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015782 ! CMP-N-acetylneuraminate transmembrane transport + +[Term] +id: GO:0005457 +name: GDP-fucose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-5653596 "Defective SLC35C1 does not transport UDP-Fuc from cytosol to Golgi lumen" +xref: Reactome:R-HSA-742345 "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen" +is_a: GO:0036080 ! purine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015783 ! GDP-fucose transmembrane transport + +[Term] +id: GO:0005458 +name: GDP-mannose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0036080 ! purine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:1990570 ! GDP-mannose transmembrane transport + +[Term] +id: GO:0005459 +name: UDP-galactose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-5652099 "Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP" +xref: Reactome:R-HSA-735702 "SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP" +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0072334 ! UDP-galactose transmembrane transport + +[Term] +id: GO:0005460 +name: UDP-glucose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015786 ! UDP-glucose transmembrane transport + +[Term] +id: GO:0005461 +name: UDP-glucuronic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-174368 "SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen" +xref: Reactome:R-HSA-5603297 "Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc" +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015787 ! UDP-glucuronic acid transmembrane transport + +[Term] +id: GO:0005462 +name: UDP-N-acetylglucosamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-5653622 "Defective SLC35A3 does not exchange UDP-GlcNAc for UMP" +xref: Reactome:R-HSA-741450 "SLC35A3 exchanges UDP-GlcNAc for UMP" +xref: Reactome:R-HSA-742354 "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:1990569 ! UDP-N-acetylglucosamine transmembrane transport + +[Term] +id: GO:0005463 +name: UDP-N-acetylgalactosamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015789 ! UDP-N-acetylgalactosamine transmembrane transport + +[Term] +id: GO:0005464 +name: UDP-xylose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate." [GOC:ai] +xref: Reactome:R-HSA-742373 "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015165 ! pyrimidine nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0015790 ! UDP-xylose transmembrane transport + +[Term] +id: GO:0005468 +name: obsolete small-molecule carrier or transporter +namespace: molecular_function +alt_id: GO:0005453 +alt_id: GO:0005454 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not provide a useful functional classification. +synonym: "small-molecule carrier or transporter" EXACT [] +is_obsolete: true +consider: GO:0005215 + +[Term] +id: GO:0005469 +name: succinate:fumarate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out)." [TC:2.A.29.13.1] +is_a: GO:0015138 ! fumarate transmembrane transporter activity +is_a: GO:0015141 ! succinate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0005471 +name: ATP:ADP antiporter activity +namespace: molecular_function +alt_id: GO:0005349 +def: "Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out)." [TC:2.A.29.1.1] +synonym: "adenine nucleotide translocase" EXACT [] +synonym: "ADP/ATP carrier protein" EXACT [] +synonym: "ADP/ATP translocase" EXACT [] +synonym: "ATP/ADP exchange" EXACT [] +synonym: "ATP/ADP exchanger" EXACT [] +is_a: GO:0005347 ! ATP transmembrane transporter activity +is_a: GO:0015217 ! ADP transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0005476 +name: carnitine:acyl carnitine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial)." [PMID:9032458] +synonym: "carnitine/acyl carnitine carrier activity" EXACT [] +synonym: "carnitine:acyl carnitine carrier activity" EXACT [] +synonym: "fatty acyl carnitine carrier" EXACT [] +is_a: GO:0015226 ! carnitine transmembrane transporter activity +is_a: GO:0015227 ! acyl carnitine transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0005477 +name: pyruvate secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "pyruvate carrier activity" RELATED [] +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +is_a: GO:0050833 ! pyruvate transmembrane transporter activity + +[Term] +id: GO:0005479 +name: obsolete vacuolar assembly +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a biological process and not a molecular function. +synonym: "vacuolar assembly" EXACT [] +is_obsolete: true +replaced_by: GO:0007033 + +[Term] +id: GO:0005480 +name: obsolete vesicle transport +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a biological process and not a molecular function. +synonym: "vesicle transport" EXACT [] +is_obsolete: true +replaced_by: GO:0016192 + +[Term] +id: GO:0005481 +name: obsolete vesicle fusion +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a biological process and not a molecular function. +synonym: "vesicle fusion" EXACT [] +is_obsolete: true +consider: GO:0006906 +consider: GO:0007086 +consider: GO:0016189 +consider: GO:0016192 +consider: GO:0019817 + +[Term] +id: GO:0005482 +name: obsolete vesicle targeting +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a biological process and not a molecular function. +synonym: "vesicle targeting" EXACT [] +is_obsolete: true +consider: GO:0006903 +consider: GO:0016080 + +[Term] +id: GO:0005483 +name: soluble NSF attachment protein activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex." [GOC:mah, PMID:14570579, PMID:15556857] +synonym: "SNAP" EXACT [] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16807 xsd:anyURI + +[Term] +id: GO:0005484 +name: SNAP receptor activity +namespace: molecular_function +alt_id: GO:0005485 +alt_id: GO:0005486 +def: "Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion." [GOC:mah, PMID:14570579] +subset: goslim_chembl +synonym: "Q-SNARE activity" NARROW [] +synonym: "R-SNARE activity" NARROW [] +synonym: "SNAP-25" NARROW [] +synonym: "SNARE" EXACT [] +synonym: "t-SNARE activity" NARROW [] +synonym: "v-SNARE activity" NARROW [] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +relationship: part_of GO:0061025 ! membrane fusion + +[Term] +id: GO:0005488 +name: binding +namespace: molecular_function +def: "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732] +comment: Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children. +subset: gocheck_do_not_annotate +subset: goslim_pir +subset: goslim_plant +synonym: "ligand" NARROW [] +xref: Wikipedia:Binding_(molecular) +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0005489 +name: obsolete electron transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells." [GOC:ai] +comment: This term was made obsolete because the activity described by the definition does not exist. +synonym: "class I cytochrome c" RELATED [] +synonym: "class II cytochrome c" RELATED [] +synonym: "class IIa cytochrome c" RELATED [] +synonym: "class IIb cytochrome c" RELATED [] +synonym: "class III cytochrome c" RELATED [] +synonym: "class IV cytochrome c" RELATED [] +synonym: "cytochrome b" RELATED [] +synonym: "cytochrome b5" RELATED [] +synonym: "cytochrome c3 (tetraheme)" RELATED [] +synonym: "cytochrome c554" RELATED [] +synonym: "cytochrome c7 (triheme)" RELATED [] +synonym: "cytochrome d" RELATED [] +synonym: "diheme class I cytochrome c" RELATED [] +synonym: "electron transfer carrier" RELATED [] +synonym: "electron transporter activity" EXACT [] +synonym: "flavin-containing electron transporter" RELATED [] +synonym: "flavodoxin" RELATED [] +synonym: "high-molecular-weight cytochrome c (hexadecaheme)" RELATED [] +synonym: "monoheme class I cytochrome c" RELATED [] +synonym: "nonaheme cytochrome c" RELATED [] +synonym: "respiratory chain cytochrome b6" RELATED [] +synonym: "Rieske iron-sulfur protein" RELATED [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0005490 +name: obsolete cytochrome P450 +namespace: molecular_function +def: "OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates." [ISBN:0198547684] +comment: This term was made obsolete because its definition was changed and because it represents a gene product. +synonym: "cytochrome P450" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005496 +name: steroid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." [GOC:jl, ISBN:0198506732] +subset: goslim_pir +is_a: GO:0008289 ! lipid binding +is_a: GO:0097159 ! organic cyclic compound binding + +[Term] +id: GO:0005497 +name: androgen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any androgen, male sex hormones." [GOC:jl] +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0005499 +name: vitamin D binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [GOC:mah, ISBN:0471331309] +synonym: "calciferol binding" NARROW [] +synonym: "cholecalciferol binding" NARROW [] +synonym: "ergocalciferol binding" NARROW [] +is_a: GO:0005496 ! steroid binding +is_a: GO:0019842 ! vitamin binding + +[Term] +id: GO:0005500 +name: juvenile hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with juvenile hormone, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:jl, ISBN:0198506732] +is_a: GO:0019840 ! isoprenoid binding +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0005501 +name: retinoid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity." [GOC:jl, ISBN:0198506732] +xref: Reactome:R-HSA-2454113 "RBP3 transports 11cRAL to rod photoreceptor outer segment" +xref: Reactome:R-HSA-2464809 "RBP3 regulates the transport of atROL from ROS to RPE" +xref: Reactome:R-HSA-2465934 "11cROL translocates from Muller cells to cone photoreceptor cells" +xref: Reactome:R-HSA-2465938 "RBP3 regulates atROL taken up by Muller cells" +is_a: GO:0019840 ! isoprenoid binding + +[Term] +id: GO:0005502 +name: 11-cis retinal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A." [PMID:24403072] +synonym: "11-cis retinaldehyde binding" EXACT [] +synonym: "11-cis-retinal binding" NARROW [] +synonym: "vitamin A binding" BROAD [] +is_a: GO:0016918 ! retinal binding + +[Term] +id: GO:0005503 +name: all-trans retinal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A." [GOC:curators] +synonym: "all-trans retinaldehyde binding" EXACT [] +synonym: "trans retinal binding" EXACT [] +synonym: "visual yellow binding" EXACT [] +synonym: "vitamin A binding" BROAD [] +synonym: "xanthopsin" RELATED [] +is_a: GO:0016918 ! retinal binding + +[Term] +id: GO:0005504 +name: fatty acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732] +is_a: GO:0008289 ! lipid binding +is_a: GO:0033293 ! monocarboxylic acid binding + +[Term] +id: GO:0005505 +name: obsolete heavy metal binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:kd, GOC:mah] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "heavy metal binding" EXACT [] +is_obsolete: true +consider: GO:0046872 + +[Term] +id: GO:0005506 +name: iron ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with iron (Fe) ions." [GOC:ai] +synonym: "iron binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0005507 +name: copper ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with copper (Cu) ions." [GOC:ai] +synonym: "copper binding" EXACT [] +synonym: "copper/cadmium binding" BROAD [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0005508 +name: obsolete copper/cadmium binding +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a composite function. +synonym: "copper/cadmium binding" EXACT [] +is_obsolete: true +consider: GO:0005507 +consider: GO:0046870 + +[Term] +id: GO:0005509 +name: calcium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcium ions (Ca2+)." [GOC:ai] +synonym: "calcium ion storage activity" RELATED [] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0005513 +name: detection of calcium ion +namespace: biological_process +def: "The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal." [GOC:pg] +synonym: "Ca2+ ion detection" EXACT [] +synonym: "calcium ion detection" EXACT [] +synonym: "calcium ion sensing" EXACT [] +synonym: "detection of Ca2+ ion" EXACT [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0051592 ! response to calcium ion + +[Term] +id: GO:0005514 +name: obsolete calcium ion storage activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a biological process. +synonym: "calcium ion storage activity" EXACT [] +is_obsolete: true +consider: GO:0005509 +consider: GO:0051208 + +[Term] +id: GO:0005515 +name: protein binding +namespace: molecular_function +alt_id: GO:0001948 +alt_id: GO:0045308 +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "glycoprotein binding" NARROW [] +synonym: "protein amino acid binding" EXACT [] +xref: Reactome:R-HSA-170835 "An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3" +xref: Reactome:R-HSA-170846 "TGFBR2 recruits TGFBR1" +is_a: GO:0005488 ! binding + +[Term] +id: GO:0005516 +name: calmodulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states." [GOC:krc] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0005517 +name: obsolete calmodulin inhibitor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:tb] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'calmodulin activity'. +synonym: "calmodulin inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0005516 + +[Term] +id: GO:0005518 +name: collagen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:ai, ISBN:0198506732] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0005519 +name: cytoskeletal regulatory protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton." [GOC:go_curators, PMID:15163540] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0005520 +name: insulin-like growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it." [ISBN:0198506732] +subset: goslim_chembl +synonym: "IGF binding" EXACT [] +is_a: GO:0019838 ! growth factor binding + +[Term] +id: GO:0005521 +name: lamin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope." [GOC:jl, ISBN:0198506732] +synonym: "lamin/chromatin binding" BROAD [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0005522 +name: profilin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin." [ISBN:0721662544] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0005523 +name: tropomyosin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle." [GOC:curators, ISBN:0815316194] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0005524 +name: ATP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] +xref: Reactome:R-HSA-265682 "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel" +is_a: GO:0008144 ! drug binding +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0035639 ! purine ribonucleoside triphosphate binding + +[Term] +id: GO:0005525 +name: GTP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with GTP, guanosine triphosphate." [GOC:ai] +xref: Reactome:R-HSA-167429 "The receptor:G-protein complex binds GTP" +is_a: GO:0032550 ! purine ribonucleoside binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0035639 ! purine ribonucleoside triphosphate binding + +[Term] +id: GO:0005527 +name: macrolide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species." [GOC:jl, ISBN:0198506732] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0005528 +name: FK506 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506." [GOC:jl] +synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" RELATED [] +is_a: GO:0005527 ! macrolide binding + +[Term] +id: GO:0005530 +name: obsolete lectin +namespace: molecular_function +def: "OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell." [GOC:curators] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "lectin" EXACT [] +is_obsolete: true +consider: GO:0007157 +consider: GO:0030246 + +[Term] +id: GO:0005531 +name: obsolete galactose binding lectin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "galactose binding lectin" EXACT [] +is_obsolete: true +consider: GO:0005534 +consider: GO:0007157 + +[Term] +id: GO:0005532 +name: obsolete mannose binding lectin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "mannose binding lectin" EXACT [] +synonym: "mannose receptor" RELATED [] +is_obsolete: true +consider: GO:0005537 +consider: GO:0007157 + +[Term] +id: GO:0005533 +name: obsolete N-acetylgalactosamine lectin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "N-acetylgalactosamine lectin" EXACT [] +is_obsolete: true +consider: GO:0007157 +consider: GO:0046871 + +[Term] +id: GO:0005534 +name: galactose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides." [GOC:jl, ISBN:0198506732] +synonym: "galactose binding lectin" RELATED [] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0005536 +name: glucose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the D- or L-enantiomer of glucose." [GOC:jl] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0005537 +name: mannose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans." [GOC:jl, ISBN:0192800981] +subset: goslim_chembl +synonym: "mannose binding lectin" RELATED [] +xref: Reactome:R-HSA-947991 "Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi" +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0005539 +name: glycosaminoglycan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0005540 +name: hyaluronic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine." [GOC:jl] +synonym: "hyaluronan binding" EXACT [] +is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0031406 ! carboxylic acid binding + +[Term] +id: GO:0005541 +name: obsolete acyl-CoA or acyl binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it was replaced by more appropriate terms. +synonym: "acyl-CoA or acyl binding" EXACT [] +is_obsolete: true +consider: GO:0000035 +consider: GO:0000062 + +[Term] +id: GO:0005542 +name: folic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:jl, ISBN:0198506732] +synonym: "folate binding" EXACT [] +synonym: "vitamin B9 binding" EXACT [] +synonym: "vitamin M binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0033218 ! amide binding +is_a: GO:0072341 ! modified amino acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0005543 +name: phospholipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester." [ISBN:0198506732] +is_a: GO:0008289 ! lipid binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0005544 +name: calcium-dependent phospholipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium." [GOC:jl] +is_a: GO:0005543 ! phospholipid binding + +[Term] +id: GO:0005545 +name: 1-phosphatidylinositol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [ISBN:0198506732] +is_a: GO:0035091 ! phosphatidylinositol binding + +[Term] +id: GO:0005546 +name: phosphatidylinositol-4,5-bisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions." [GOC:bf, GOC:jl] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding" EXACT [] +synonym: "phosphatidylinositol 4,5-bisphosphate binding" EXACT [GOC:ebc] +synonym: "PIP2 binding" BROAD [] +synonym: "PtdIns(4,5)P2 binding" EXACT [GOC:bf] +is_a: GO:1902936 ! phosphatidylinositol bisphosphate binding + +[Term] +id: GO:0005547 +name: phosphatidylinositol-3,4,5-trisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions." [GOC:bf, GOC:jl] +synonym: "PIP3 binding" EXACT [GOC:bf] +is_a: GO:1901981 ! phosphatidylinositol phosphate binding + +[Term] +id: GO:0005548 +name: phospholipid transporter activity +namespace: molecular_function +alt_id: GO:0008497 +def: "Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester." [GOC:ai, ISBN:0198506732] +xref: Reactome:R-HSA-216757 "4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane" +xref: Reactome:R-HSA-382553 "ABCA7:Apo1A-mediated phospholipid efflux" +xref: Reactome:R-HSA-5678706 "ABCB4 transports PC from plasma membrane to extracellular region" +xref: Reactome:R-HSA-5678749 "Defective ABCB4 does not transport PC from plasma membrane to extracellular region" +xref: Reactome:R-HSA-8857662 "ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane" +xref: Reactome:R-HSA-8865637 "MFSD2A transports LPC from extracellular region to plasma membrane" +xref: Reactome:R-HSA-8867876 "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane" +is_a: GO:0005319 ! lipid transporter activity +relationship: part_of GO:0015914 ! phospholipid transport + +[Term] +id: GO:0005549 +name: odorant binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell." [GOC:jl, ISBN:0721662544] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0005550 +name: pheromone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." [GOC:ai] +is_a: GO:0005549 ! odorant binding + +[Term] +id: GO:0005551 +name: obsolete ubiquitin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a gene product. +is_obsolete: true +consider: GO:0016567 +consider: GO:0031386 + +[Term] +id: GO:0005552 +name: obsolete polyubiquitin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "polyubiquitin" EXACT [] +is_obsolete: true +consider: GO:0000209 + +[Term] +id: GO:0005553 +name: obsolete ubiquitin-ribosomal protein fusion protein +namespace: molecular_function +def: "OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein." [ISBN:0198506732] +comment: This term was made obsolete because it describes a gene product. +synonym: "ubiquitin-ribosomal protein fusion protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005555 +name: obsolete blood group antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "blood group antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005557 +name: obsolete lymphocyte antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "lymphocyte antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005558 +name: obsolete minor histocompatibility antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "minor histocompatibility antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005559 +name: obsolete ribozyme +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "ribozyme" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005561 +name: obsolete nucleic acid +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "nucleic acid" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005562 +name: obsolete RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "RNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005563 +name: obsolete transfer RNA +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "transfer RNA" EXACT [] +is_obsolete: true +replaced_by: GO:0030533 + +[Term] +id: GO:0005564 +name: obsolete cytosolic tRNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "cytosolic tRNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005565 +name: obsolete mitochondrial tRNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "mitochondrial tRNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005566 +name: obsolete ribosomal RNA +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "ribosomal RNA" EXACT [] +is_obsolete: true +consider: GO:0003735 +consider: GO:0005840 + +[Term] +id: GO:0005567 +name: obsolete cytosolic ribosomal RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "cytosolic ribosomal RNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005568 +name: obsolete mitochondrial rRNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "mitochondrial rRNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005569 +name: obsolete small nucleolar RNA +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents gene products. +synonym: "small nucleolar RNA" EXACT [] +is_obsolete: true +consider: GO:0030555 + +[Term] +id: GO:0005570 +name: obsolete small nuclear RNA +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents gene products. +synonym: "small nuclear RNA" EXACT [] +is_obsolete: true +consider: GO:0000375 +consider: GO:0017069 + +[Term] +id: GO:0005571 +name: obsolete untranslated RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "untranslated RNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005572 +name: obsolete RNA polymerase II transcribed untranslated RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "RNA polymerase II transcribed untranslated RNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005573 +name: obsolete telomerase RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it represents a gene product. +synonym: "telomerase RNA" EXACT [] +is_obsolete: true +replaced_by: GO:0000332 + +[Term] +id: GO:0005574 +name: obsolete DNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused. +synonym: "DNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005575 +name: cellular_component +namespace: cellular_component +alt_id: GO:0008372 +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome)." [GOC:pdt, NIF_Subcellular:sao1337158144] +comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "cell or subcellular entity" EXACT [] +synonym: "cellular component" EXACT [] +synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] +xref: NIF_Subcellular:sao1337158144 + +[Term] +id: GO:0005576 +name: extracellular region +namespace: cellular_component +def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] +comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "extracellular" EXACT [] +xref: Wikipedia:Extracellular +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0005577 +name: fibrinogen complex +namespace: cellular_component +def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] +synonym: "fibrinogen" EXACT [] +synonym: "fibrinogen alpha chain" NARROW [] +synonym: "fibrinogen beta chain" NARROW [] +synonym: "fibrinogen gamma chain" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0005579 +name: membrane attack complex +namespace: cellular_component +def: "A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow." [GOC:add, ISBN:0198547684, ISBN:068340007X, ISBN:0781735149] +synonym: "MAC" EXACT [] +synonym: "membrane attack complex protein alphaM chain" NARROW [] +synonym: "membrane attack complex protein beta2 chain" NARROW [] +synonym: "TCC" EXACT [] +synonym: "terminal complement complex" EXACT [] +xref: Wikipedia:Complement_membrane_attack_complex +is_a: GO:0046930 ! pore complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005580 +name: obsolete membrane attack complex protein alphaM chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "membrane attack complex protein alphaM chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005579 + +[Term] +id: GO:0005581 +name: collagen trimer +namespace: cellular_component +def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, ISBN:0721639976, PMID:19693541, PMID:21421911] +xref: Wikipedia:Collagen +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0005582 +name: collagen type XV trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils." [PMID:11158616, PMID:11937714, PMID:21421911] +is_a: GO:0098651 ! basement membrane collagen trimer + +[Term] +id: GO:0005583 +name: fibrillar collagen trimer +namespace: cellular_component +def: "Any triple helical collagen trimer that forms fibrils." [GOC:mah, ISBN:0721639976, PMID:21421911] +is_a: GO:0005581 ! collagen trimer +intersection_of: GO:0005581 ! collagen trimer +intersection_of: part_of GO:0098643 ! banded collagen fibril +disjoint_from: GO:0005598 ! short-chain collagen trimer +disjoint_from: GO:0030936 ! transmembrane collagen trimer +relationship: part_of GO:0098643 ! banded collagen fibril + +[Term] +id: GO:0005584 +name: collagen type I trimer +namespace: cellular_component +def: "A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils." [GOC:mah, GOC:sl, ISBN:0721639976] +xref: Wikipedia:Collagen_type_I +is_a: GO:0005583 ! fibrillar collagen trimer + +[Term] +id: GO:0005585 +name: collagen type II trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." [ISBN:0721639976] +xref: Wikipedia:Collagen_type_II +is_a: GO:0005583 ! fibrillar collagen trimer + +[Term] +id: GO:0005586 +name: collagen type III trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils." [ISBN:0721639976] +is_a: GO:0005583 ! fibrillar collagen trimer + +[Term] +id: GO:0005587 +name: collagen type IV trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [ISBN:0721639976, PMID:19693541, PMID:21421911] +xref: Wikipedia:Collagen_type_IV +is_a: GO:0098642 ! network-forming collagen trimer +is_a: GO:0098651 ! basement membrane collagen trimer + +[Term] +id: GO:0005588 +name: collagen type V trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils." [ISBN:0721639976] +is_a: GO:0005583 ! fibrillar collagen trimer + +[Term] +id: GO:0005589 +name: collagen type VI trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils." [ISBN:0721639976, PMID:19693541, PMID:21421911] +is_a: GO:0005581 ! collagen trimer +relationship: part_of GO:0098647 ! collagen beaded filament + +[Term] +id: GO:0005590 +name: collagen type VII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin." [ISBN:0721639976, PMID:19693541] +is_a: GO:0030934 ! anchoring collagen complex +relationship: part_of GO:0098652 ! collagen type VII anchoring fibril + +[Term] +id: GO:0005591 +name: collagen type VIII trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets." [ISBN:0721639976, PMID:21421911] +is_a: GO:0005598 ! short-chain collagen trimer +is_a: GO:0030935 ! sheet-forming collagen trimer +is_a: GO:0098651 ! basement membrane collagen trimer + +[Term] +id: GO:0005592 +name: collagen type XI trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils." [ISBN:0721639976] +is_a: GO:0005583 ! fibrillar collagen trimer + +[Term] +id: GO:0005593 +name: FACIT collagen trimer +namespace: cellular_component +def: "A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences." [ISBN:0198599587, PMID:21421911] +comment: The acronym FACIT stands for fibril-associated collagen with interrupted triple helix. +xref: Wikipedia:FACIT_collagen +is_a: GO:0005581 ! collagen trimer + +[Term] +id: GO:0005594 +name: collagen type IX trimer +namespace: cellular_component +def: "A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils." [ISBN:0721639976] +is_a: GO:0005593 ! FACIT collagen trimer + +[Term] +id: GO:0005595 +name: collagen type XII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures." [ISBN:0721639976] +is_a: GO:0005593 ! FACIT collagen trimer +is_a: GO:0030934 ! anchoring collagen complex + +[Term] +id: GO:0005596 +name: collagen type XIV trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures." [ISBN:0721639976] +is_a: GO:0005593 ! FACIT collagen trimer +is_a: GO:0030934 ! anchoring collagen complex + +[Term] +id: GO:0005597 +name: collagen type XVI trimer +namespace: cellular_component +def: "A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils." [GOC:mah, PMID:12782140] +is_a: GO:0005593 ! FACIT collagen trimer + +[Term] +id: GO:0005598 +name: short-chain collagen trimer +namespace: cellular_component +def: "Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils." [ISBN:0198599587] +is_a: GO:0005581 ! collagen trimer + +[Term] +id: GO:0005599 +name: collagen type X trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets)." [ISBN:0721639976, PMID:21421911] +comment: Collagen X trimers have been observed to form hexagonal lattices in vitro, but in vivo they have been found in a fibril associated form (PMID:19693541). +is_a: GO:0005598 ! short-chain collagen trimer +is_a: GO:0030935 ! sheet-forming collagen trimer + +[Term] +id: GO:0005600 +name: collagen type XIII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane." [GOC:bhm, GOC:dos, ISBN:0721639976] +is_a: GO:0030936 ! transmembrane collagen trimer + +[Term] +id: GO:0005601 +name: classical-complement-pathway C3/C5 convertase complex +namespace: cellular_component +def: "A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone." [BRENDA:3.4.21.43, GOC:mah, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Complement.html] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0005602 +name: complement component C1 complex +namespace: cellular_component +def: "A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains." [GOC:add, ISBN:0781735149] +synonym: "complement component C1q complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0062167 ! complement component C1q complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0005603 +name: obsolete complement component C2 complex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because prior to cleavage, complement component C2 is a single polypeptide rather than a complex, and after cleavage the products do not remain physically associated; there is thus no known biological entity corresponding to "complement C2 complex". +synonym: "complement component C2 complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005604 +name: basement membrane +namespace: cellular_component +alt_id: GO:0005605 +alt_id: GO:0008003 +def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684, PMID:22505934] +comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer. +synonym: "basal lamina" RELATED [] +synonym: "basement lamina" RELATED [] +synonym: "lamina densa" RELATED [] +xref: Wikipedia:Basement_membrane +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0005606 +name: laminin-1 complex +namespace: cellular_component +def: "A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-111 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005607 +name: laminin-2 complex +namespace: cellular_component +def: "A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-211 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005608 +name: laminin-3 complex +namespace: cellular_component +def: "A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains." [MEDLINE:95005761] +synonym: "laminin-121 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005609 +name: laminin-4 complex +namespace: cellular_component +def: "A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-221 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005610 +name: laminin-5 complex +namespace: cellular_component +def: "A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-332 complex" NARROW [GOC:dph, PMID:15979864] +synonym: "laminin-3A32 complex" EXACT [PMID:15979864] +synonym: "laminin-5A complex" EXACT [PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005611 +name: laminin-6 complex +namespace: cellular_component +def: "A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-311 complex" EXACT [GOC:dph, PMID:15979864] +synonym: "laminin-6A complex" EXACT [PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005612 +name: laminin-7 complex +namespace: cellular_component +def: "A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-321 complex" NARROW [GOC:dph, PMID:15979864] +synonym: "laminin-7A" EXACT [PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0005613 +name: obsolete laminin receptor protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family. +synonym: "laminin receptor protein" EXACT [] +is_obsolete: true +consider: GO:0008305 + +[Term] +id: GO:0005614 +name: interstitial matrix +namespace: cellular_component +def: "A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens." [PMID:8450001] +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0005615 +name: extracellular space +namespace: cellular_component +def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] +comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +synonym: "intercellular space" RELATED [] +xref: NIF_Subcellular:sao1425028079 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0005616 +name: larval serum protein complex +namespace: cellular_component +def: "A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins." [GOC:jl, PMID:6781759] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0005617 +name: obsolete larval serum protein-1 +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "larval serum protein-1" EXACT [] +synonym: "LSP1" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005618 +name: cell wall +namespace: cellular_component +def: "The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins." [GOC:giardia, ISBN:0198547684, PMID:15134259, Wikipedia:Microbial_cyst] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: Wikipedia:Cell_wall +is_a: GO:0030312 ! external encapsulating structure +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0005619 +name: ascospore wall +namespace: cellular_component +def: "The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi." [GOC:vw, ISBN:0879693568] +synonym: "fungal-type spore wall" BROAD [GOC:mah] +is_a: GO:0009277 ! fungal-type cell wall +is_a: GO:0031160 ! spore wall + +[Term] +id: GO:0005621 +name: cellular bud scar +namespace: cellular_component +def: "Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age." [GOC:rn, PMID:14600225, PMID:2005820] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009277 ! fungal-type cell wall + +[Term] +id: GO:0005622 +name: intracellular +namespace: cellular_component +def: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] +subset: gocheck_do_not_annotate +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_plant +synonym: "internal to cell" EXACT [] +synonym: "nucleocytoplasm" RELATED [GOC:mah] +synonym: "protoplasm" EXACT [] +synonym: "protoplast" RELATED [GOC:mah] +xref: Wikipedia:Intracellular +is_a: GO:0005575 ! cellular_component + +[Term] +id: GO:0005623 +name: cell +namespace: cellular_component +def: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +xref: NIF_Subcellular:sao1813327414 +xref: Wikipedia:Cell_(biology) +is_a: GO:0005575 ! cellular_component +property_value: IAO:0000589 "cell and encapsulating structures" xsd:string + +[Term] +id: GO:0005624 +name: obsolete membrane fraction +namespace: cellular_component +def: "OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes." [GOC:ma] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "membrane fraction" EXACT [] +is_obsolete: true +consider: GO:0016020 + +[Term] +id: GO:0005625 +name: obsolete soluble fraction +namespace: cellular_component +def: "OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water." [GOC:ma] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "soluble" BROAD [] +synonym: "soluble fraction" EXACT [] +is_obsolete: true +consider: GO:0005575 + +[Term] +id: GO:0005626 +name: obsolete insoluble fraction +namespace: cellular_component +def: "OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water." [GOC:ma] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "insoluble fraction" EXACT [] +synonym: "particle-bound" RELATED [] +is_obsolete: true +consider: GO:0005575 + +[Term] +id: GO:0005627 +name: obsolete ascus +namespace: cellular_component +def: "OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number)." [ISBN:0198547684] +comment: This term was made obsolete because it is a structure that contains cell (ascospores) rather than a cellular component. To update annotations, consider the external ontology term 'ascus ; FAO:0000014'. +synonym: "ascus" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005628 +name: prospore membrane +namespace: cellular_component +def: "The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe." [ISBN:0879693649] +synonym: "ascospore-type prospore membrane" EXACT [GOC:mah] +synonym: "forespore membrane" RELATED [] +synonym: "FSM" EXACT [] +is_a: GO:0016020 ! membrane +relationship: part_of GO:0042764 ! ascospore-type prospore + +[Term] +id: GO:0005630 +name: dityrosine layer of spore wall +namespace: cellular_component +def: "The outermost layer of the spore wall, as described in Saccharomyces." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005619 ! ascospore wall + +[Term] +id: GO:0005631 +name: chitosan layer of spore wall +namespace: cellular_component +def: "The second outermost layer of the spore wall, as described in Saccharomyces." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005619 ! ascospore wall + +[Term] +id: GO:0005632 +name: inner layer of spore wall +namespace: cellular_component +def: "Either of the two innermost layers of the spore wall, as described in Saccharomyces." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005619 ! ascospore wall + +[Term] +id: GO:0005633 +name: ascus lipid droplet +namespace: cellular_component +def: "Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins." [GOC:mah, PMID:12702293] +synonym: "ascus lipid particle" EXACT [] +is_a: GO:0005811 ! lipid droplet + +[Term] +id: GO:0005634 +name: nucleus +namespace: cellular_component +def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "cell nucleus" EXACT [] +synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] +xref: NIF_Subcellular:sao1702920020 +xref: Wikipedia:Cell_nucleus +is_a: GO:0043231 ! intracellular membrane-bounded organelle + +[Term] +id: GO:0005635 +name: nuclear envelope +namespace: cellular_component +alt_id: GO:0005636 +def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +xref: Wikipedia:Nuclear_envelope +is_a: GO:0031967 ! organelle envelope +relationship: part_of GO:0005634 ! nucleus +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0005637 +name: nuclear inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope." [GOC:ma] +synonym: "inner envelope" BROAD [] +synonym: "inner nuclear membrane" EXACT [GOC:kmv, GOC:vw, PMID:21411627] +xref: NIF_Subcellular:sao1612527463 +is_a: GO:0019866 ! organelle inner membrane +is_a: GO:0031965 ! nuclear membrane + +[Term] +id: GO:0005638 +name: lamin filament +namespace: cellular_component +def: "Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C." [ISBN:0198547684] +synonym: "type V intermediate filament" EXACT [] +is_a: GO:0005882 ! intermediate filament +intersection_of: GO:0005882 ! intermediate filament +intersection_of: part_of GO:0005652 ! nuclear lamina +relationship: part_of GO:0005652 ! nuclear lamina + +[Term] +id: GO:0005639 +name: integral component of nuclear inner membrane +namespace: cellular_component +def: "The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:go_curators] +synonym: "integral to nuclear inner membrane" NARROW [] +is_a: GO:0031229 ! intrinsic component of nuclear inner membrane +is_a: GO:0031301 ! integral component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005637 ! nuclear inner membrane + +[Term] +id: GO:0005640 +name: nuclear outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] +synonym: "outer envelope" BROAD [] +synonym: "perinuclear membrane" EXACT [] +xref: NIF_Subcellular:sao1617136075 +is_a: GO:0031965 ! nuclear membrane +is_a: GO:0031968 ! organelle outer membrane +relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network + +[Term] +id: GO:0005641 +name: nuclear envelope lumen +namespace: cellular_component +alt_id: GO:0005653 +def: "The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide." [GOC:ai] +comment: Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'. +synonym: "nuclear intermembrane space" EXACT [] +synonym: "nuclear membrane lumen" RELATED [] +synonym: "perinuclear space" EXACT [] +is_a: GO:0031970 ! organelle envelope lumen +relationship: part_of GO:0005635 ! nuclear envelope + +[Term] +id: GO:0005642 +name: annulate lamellae +namespace: cellular_component +def: "Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER." [PMID:12631728] +is_a: GO:0098589 ! membrane region +relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network + +[Term] +id: GO:0005643 +name: nuclear pore +namespace: cellular_component +alt_id: GO:0005644 +def: "Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined." [ISBN:0198547684] +subset: goslim_pir +synonym: "NPC" EXACT [] +synonym: "nuclear pore complex" EXACT [] +synonym: "nuclear pore membrane protein" NARROW [] +synonym: "nucleopore" EXACT [GOC:al, PMID:7603572] +xref: NIF_Subcellular:sao220861693 +xref: Wikipedia:Nuclear_pore +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005635 ! nuclear envelope + +[Term] +id: GO:0005645 +name: obsolete RAN-binding protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "RAN-binding protein" EXACT [] +is_obsolete: true +replaced_by: GO:0008536 +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 + +[Term] +id: GO:0005646 +name: obsolete importin +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "importin" EXACT [] +synonym: "karyopherin" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 +consider: GO:0017056 + +[Term] +id: GO:0005647 +name: obsolete importin, alpha-subunit +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "importin, alpha-subunit" EXACT [] +synonym: "karyopherin-alpha" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 +consider: GO:0017056 + +[Term] +id: GO:0005648 +name: obsolete importin, beta-subunit +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "importin, beta-subunit" EXACT [] +synonym: "karyopherin-beta1" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 +consider: GO:0017056 + +[Term] +id: GO:0005649 +name: obsolete transportin +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "karyopherin-beta2" EXACT [] +synonym: "transportin" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 + +[Term] +id: GO:0005650 +name: obsolete importin, alpha-subunit transport factor +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "CAS" RELATED [] +synonym: "importin, alpha-subunit transport factor" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 + +[Term] +id: GO:0005651 +name: obsolete exportin +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "exportin" EXACT [] +is_obsolete: true +consider: GO:0005634 +consider: GO:0005643 +consider: GO:0005737 +consider: GO:0017056 + +[Term] +id: GO:0005652 +name: nuclear lamina +namespace: cellular_component +def: "The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane." [ISBN:0198506732, ISBN:0716731363] +xref: NIF_Subcellular:sao1455996588 +xref: Wikipedia:Nuclear_lamina +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0034399 ! nuclear periphery + +[Term] +id: GO:0005654 +name: nucleoplasm +namespace: cellular_component +def: "That part of the nuclear content other than the chromosomes or the nucleolus." [GOC:ma, ISBN:0124325653] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +xref: NIF_Subcellular:sao661522542 +xref: Wikipedia:Nucleoplasm +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0005655 +name: nucleolar ribonuclease P complex +namespace: cellular_component +def: "A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules." [GOC:mah, PMID:12045094] +synonym: "nucleolar RNase P complex" EXACT [] +is_a: GO:0030681 ! multimeric ribonuclease P complex +intersection_of: GO:0030677 ! ribonuclease P complex +intersection_of: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0005656 +name: nuclear pre-replicative complex +namespace: cellular_component +def: "A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins." [PMID:15222894] +synonym: "eukaryotic pre-replicative complex" EXACT [GOC:bf, GOC:bhm, GOC:jh2] +synonym: "pre-RC" RELATED [] +synonym: "pre-replicative complex" BROAD [GOC:bf, GOC:bhm, GOC:jh2] +is_a: GO:0036387 ! pre-replicative complex +relationship: has_part GO:0000808 ! origin recognition complex +relationship: has_part GO:0042555 ! MCM complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0005657 +name: replication fork +namespace: cellular_component +def: "The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:mah, ISBN:0198547684] +synonym: "replication focus" RELATED [] +xref: Wikipedia:Replication_fork +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0005658 +name: alpha DNA polymerase:primase complex +namespace: cellular_component +def: "A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis." [GOC:mah, PMID:11395402, PMID:26975377] +synonym: "DNA polymerase alpha:primase complex" EXACT [] +synonym: "heterotetrameric polymerase alpha holoenzyme" EXACT [] +synonym: "pol-prim" RELATED [] +synonym: "primosome" BROAD [] +is_a: GO:0042575 ! DNA polymerase complex +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex +relationship: part_of GO:0043601 ! nuclear replisome + +[Term] +id: GO:0005660 +name: obsolete delta-DNA polymerase cofactor complex +namespace: cellular_component +def: "OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP." [GOC:jl] +comment: This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RFC is not used in current literature. +synonym: "delta DNA polymerase cofactor complex" EXACT [] +synonym: "delta-DNA polymerase cofactor complex" EXACT [] +is_obsolete: true +consider: GO:0005663 +consider: GO:0043626 + +[Term] +id: GO:0005662 +name: DNA replication factor A complex +namespace: cellular_component +def: "A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa." [PMID:9242902] +synonym: "replication protein A" EXACT [] +synonym: "RPA" EXACT [] +xref: Wikipedia:Replication_protein_A +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043601 ! nuclear replisome + +[Term] +id: GO:0005663 +name: DNA replication factor C complex +namespace: cellular_component +def: "A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides." [PMID:14614842, PMID:14646196, PMID:16172520] +subset: goslim_pir +synonym: "activator 1 complex" EXACT [] +synonym: "RFC complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005657 ! replication fork +property_value: RO:0002161 NCBITaxon:2 + +[Term] +id: GO:0005664 +name: nuclear origin of replication recognition complex +namespace: cellular_component +def: "A multisubunit complex that is located at the replication origins of a chromosome in the nucleus." [GOC:elh] +synonym: "eukaryotic ORC" EXACT [] +synonym: "nuclear ORC" EXACT [] +is_a: GO:0000808 ! origin recognition complex +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0005665 +name: RNA polymerase II, core complex +namespace: cellular_component +def: "RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] +synonym: "DNA-directed RNA polymerase II, core complex" EXACT [] +synonym: "RNA polymerase II complex" BROAD [] +synonym: "RNAP II complex" BROAD [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex +intersection_of: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: part_of GO:0016591 ! RNA polymerase II, holoenzyme +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005666 +name: RNA polymerase III complex +namespace: cellular_component +def: "RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] +synonym: "DNA-directed RNA polymerase III activity" RELATED [] +synonym: "DNA-directed RNA polymerase III complex" EXACT [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex + +[Term] +id: GO:0005667 +name: transcription regulator complex +namespace: cellular_component +alt_id: GO:0044797 +alt_id: GO:0044798 +def: "A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription." [GOC:jl] +subset: goslim_pir +synonym: "cytoplasmic transcription factor complex" RELATED [] +synonym: "nuclear transcription factor complex" RELATED [] +synonym: "transcription factor complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2013-08-28T12:11:37Z + +[Term] +id: GO:0005668 +name: RNA polymerase transcription factor SL1 complex +namespace: cellular_component +def: "A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48." [PMID:15691654] +synonym: "selectivity factor SL1 complex" EXACT [GOC:mah] +synonym: "TIF-IB" EXACT [CORUM:480, PMID:15691654] +is_a: GO:0000120 ! RNA polymerase I transcription regulator complex + +[Term] +id: GO:0005669 +name: transcription factor TFIID complex +namespace: cellular_component +def: "A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters." [GOC:krc, GOC:mah, ISBN:0471953393, ISBN:0879695501] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005670 +name: obsolete transcription-activating factor, 30kD +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "transcription-activating factor, 30kD" EXACT [] +is_obsolete: true +replaced_by: GO:0005669 + +[Term] +id: GO:0005671 +name: Ada2/Gcn5/Ada3 transcription activator complex +namespace: cellular_component +alt_id: GO:0002928 +def: "A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues." [PMID:10637607] +comment: In human, this complex is composed of GCN5 or PCAF, ADA2a, ADA3, ZZZ3, ATAC2, SGF29, HCF1, WDR5,YEATS2, NC2-beta, and MBIP. +synonym: "Ada Two-A containing complex" EXACT [GOC:rl, PMID:18838386] +synonym: "Ada-Two-A-containing complex" EXACT [] +synonym: "ATAC complex" EXACT [GOC:rl, PMID:18838386] +is_a: GO:1902562 ! H4 histone acetyltransferase complex + +[Term] +id: GO:0005672 +name: transcription factor TFIIA complex +namespace: cellular_component +def: "A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12)." [GOC:jl, PMID:17560669] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005673 +name: transcription factor TFIIE complex +namespace: cellular_component +def: "A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH." [GOC:jl, PMID:16547462] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005674 +name: transcription factor TFIIF complex +namespace: cellular_component +def: "A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation." [GOC:jl, PMID:7597077] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005675 +name: transcription factor TFIIH holo complex +namespace: cellular_component +def: "A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex." [GOC:ew, GOC:krc, PMID:14500720, PMID:22308316, PMID:22572993, PMID:7813015] +synonym: "holo TFIIH complex" EXACT [] +is_a: GO:0032806 ! carboxy-terminal domain protein kinase complex +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: has_part GO:0000439 ! transcription factor TFIIH core complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0005677 +name: chromatin silencing complex +namespace: cellular_component +def: "Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing." [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0005678 +name: obsolete chromatin assembly complex +namespace: cellular_component +def: "OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure." [GOC:mah] +comment: This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge. +synonym: "chromatin assembly complex" EXACT [] +synonym: "nucleosome assembly complex" NARROW [] +is_obsolete: true +consider: GO:0031497 + +[Term] +id: GO:0005680 +name: anaphase-promoting complex +namespace: cellular_component +def: "A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B." [GOC:jh, GOC:vw, PMID:10465783, PMID:10611969] +comment: Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein. +synonym: "anaphase promoting complex" EXACT [] +synonym: "APC" BROAD [] +synonym: "cyclosome" EXACT [] +xref: Wikipedia:Anaphase-promoting_complex +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0005681 +name: spliceosomal complex +namespace: cellular_component +def: "Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA." [GOC:editors, GOC:mah, ISBN:0198547684, PMID:19239890] +subset: goslim_pir +synonym: "spliceosome" BROAD [] +synonym: "spliceosome complex" EXACT [] +xref: Wikipedia:Spliceosome +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0005682 +name: U5 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U5." [GOC:krc, GOC:mah] +synonym: "snRNP U5" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005683 +name: U7 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs." [PMID:12872004] +synonym: "snRNP U7" EXACT [GOC:mah] +is_a: GO:0030532 ! small nuclear ribonucleoprotein complex + +[Term] +id: GO:0005684 +name: U2-type spliceosomal complex +namespace: cellular_component +def: "Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends." [GOC:krc, GOC:mah, PMID:11343900] +comment: A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP. +synonym: "GT-AG spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "major (U2-type) spliceosomal complex" EXACT [GOC:krc, GOC:mah] +synonym: "major spliceosomal complex" EXACT [GOC:krc, GOC:mah] +is_a: GO:0005681 ! spliceosomal complex + +[Term] +id: GO:0005685 +name: U1 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U1." [GOC:krc, GOC:mah] +synonym: "snRNP U1" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005686 +name: U2 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U2." [GOC:krc, GOC:mah] +comment: U2 snRNP refers to the U2 small nuclear RNA and the proteins that associate with it. U2 snRNP is not considered to be a type of spliceosomal complex by itself. +synonym: "17S U2 snRNP" NARROW [] +synonym: "snRNP U2" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005687 +name: U4 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U4." [GOC:krc, GOC:mah] +synonym: "snRNP U4" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005688 +name: U6 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U6." [GOC:krc, GOC:mah] +synonym: "snRNP U6" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex +relationship: has_part GO:0120115 ! Lsm2-8 complex + +[Term] +id: GO:0005689 +name: U12-type spliceosomal complex +namespace: cellular_component +def: "Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site." [GOC:krc, GOC:mah, PMID:11574683, PMID:11971955] +synonym: "AT-AC spliceosomal complex" NARROW [GOC:krc, GOC:mah] +synonym: "minor (U12-type) spliceosomal complex" EXACT [GOC:mah] +synonym: "minor spliceosomal complex" EXACT [GOC:krc, GOC:mah] +xref: Wikipedia:Minor_spliceosome +is_a: GO:0005681 ! spliceosomal complex + +[Term] +id: GO:0005690 +name: U4atac snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U4atac." [GOC:krc, GOC:mah] +synonym: "snRNP U4atac" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005691 +name: U6atac snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U6atac." [GOC:krc, GOC:mah] +synonym: "snRNP U6atac" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005692 +name: U11 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U11." [GOC:krc, GOC:mah] +synonym: "12S U11 snRNP" NARROW [] +synonym: "snRNP U11" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005693 +name: U12 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains small nuclear RNA U12." [GOC:krc, GOC:mah] +synonym: "snRNP U12" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0005694 +name: chromosome +namespace: cellular_component +def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] +comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_yeast +synonym: "chromatid" RELATED [] +synonym: "interphase chromosome" NARROW [] +synonym: "prophase chromosome" NARROW [] +xref: Wikipedia:Chromosome +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0005695 +name: obsolete chromatid +namespace: cellular_component +def: "OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis." [ISBN:0198506732] +comment: This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions. +synonym: "chromatid" EXACT [] +is_obsolete: true +consider: GO:0000793 +consider: GO:0000794 +consider: GO:0005694 + +[Term] +id: GO:0005696 +name: obsolete telomere +namespace: cellular_component +def: "OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA." [ISBN:0198506732, PMID:11352055] +comment: This term was made obsolete because the definition was too sequence oriented and too restrictive. +synonym: "telomere" EXACT [] +is_obsolete: true +consider: GO:0000781 +consider: GO:0000782 + +[Term] +id: GO:0005697 +name: telomerase holoenzyme complex +namespace: cellular_component +def: "Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits." [PMID:11884619] +subset: goslim_pir +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0005698 +name: obsolete centromere +namespace: cellular_component +def: "OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid." [ISBN:0198506732] +comment: This term was made obsolete because it is a genetically defined region and not a specific subcellular localization. +synonym: "centromere" EXACT [] +is_obsolete: true +consider: GO:0000775 + +[Term] +id: GO:0005700 +name: polytene chromosome +namespace: cellular_component +def: "A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732] +xref: Wikipedia:Polytene_chromosome +is_a: GO:0005694 ! chromosome + +[Term] +id: GO:0005701 +name: polytene chromosome chromocenter +namespace: cellular_component +def: "A region at which the centric regions of polytene chromosomes are joined together." [GOC:bf, ISBN:0120649012] +synonym: "polytene chromosome chromocentre" EXACT [] +is_a: GO:0010369 ! chromocenter +intersection_of: GO:0010369 ! chromocenter +intersection_of: part_of GO:0005700 ! polytene chromosome +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005702 +name: polytene chromosome weak point +namespace: cellular_component +def: "A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization." [GOC:bf, ISBN:0120649012] +synonym: "constriction" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005703 +name: polytene chromosome puff +namespace: cellular_component +def: "A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription." [GOC:bf, ISBN:0120649012] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005704 +name: polytene chromosome band +namespace: cellular_component +def: "A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band." [GOC:bf, PMID:11361342] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005705 +name: polytene chromosome interband +namespace: cellular_component +def: "A stretch of less tightly packed chromatin along the polytene chromosome, found between bands." [GOC:bf, PMID:11361342] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005706 +name: polytene chromosome ectopic fiber +namespace: cellular_component +def: "A thread-like connection joining two regions of ectopically paired polytene chromosomes." [GOC:bf, ISBN:0120649012] +synonym: "polytene chromosome ectopic fibre" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005700 ! polytene chromosome + +[Term] +id: GO:0005707 +name: obsolete interphase chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently." [GOC:ai, ISBN:0815316194] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "interphase chromosome" EXACT [] +is_obsolete: true +consider: GO:0005694 + +[Term] +id: GO:0005708 +name: obsolete mitotic chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome involved in the process of mitosis." [GOC:ai] +comment: This term was made obsolete because it is based on a process. +synonym: "mitotic chromosome" EXACT [] +is_obsolete: true +consider: GO:0000793 +consider: GO:0000794 + +[Term] +id: GO:0005709 +name: obsolete prophase chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the cell during prophase." [GOC:ai] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "prophase chromosome" EXACT [] +is_obsolete: true +consider: GO:0005694 + +[Term] +id: GO:0005710 +name: obsolete metaphase chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins." [GOC:ai] +comment: This term was made obsolete because it is based on a temporal division of the cell cycle. +synonym: "metaphase chromosome" EXACT [] +is_obsolete: true +consider: GO:0000793 +consider: GO:0000794 + +[Term] +id: GO:0005711 +name: obsolete meiotic chromosome +namespace: cellular_component +def: "OBSOLETE. A chromosome involved in the process of meiosis." [GOC:ai] +comment: This term was made obsolete because it is based on a process. +synonym: "meiotic chromosome" EXACT [] +is_obsolete: true +consider: GO:0000794 + +[Term] +id: GO:0005712 +name: chiasma +namespace: cellular_component +def: "A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over." [ISBN:0198506732] +xref: Wikipedia:Chiasma_(genetics) +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0005713 +name: recombination nodule +namespace: cellular_component +def: "An electron dense structure that is associated with meiotic chromosomes." [GOC:elh] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0005714 +name: early recombination nodule +namespace: cellular_component +def: "An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I." [GOC:elh] +is_a: GO:0005713 ! recombination nodule + +[Term] +id: GO:0005715 +name: late recombination nodule +namespace: cellular_component +def: "An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I." [GOC:elh] +is_a: GO:0005713 ! recombination nodule + +[Term] +id: GO:0005719 +name: nuclear euchromatin +namespace: cellular_component +def: "The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin." [ISBN:0198506732] +is_a: GO:0000790 ! nuclear chromatin +is_a: GO:0000791 ! euchromatin +intersection_of: GO:0000791 ! euchromatin +intersection_of: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0005720 +name: nuclear heterochromatin +namespace: cellular_component +def: "A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin." [ISBN:0198506732] +is_a: GO:0000790 ! nuclear chromatin +is_a: GO:0000792 ! heterochromatin +intersection_of: GO:0000792 ! heterochromatin +intersection_of: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0005721 +name: pericentric heterochromatin +namespace: cellular_component +def: "Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3." [PMID:12019236, PMID:20206496, PMID:22729156] +synonym: "centric heterochromatin" EXACT [] +synonym: "centromeric heterochromatin" EXACT [GOC:dph] +is_a: GO:0000792 ! heterochromatin +intersection_of: GO:0000792 ! heterochromatin +intersection_of: part_of GO:0000775 ! chromosome, centromeric region +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0005722 +name: beta-heterochromatin +namespace: cellular_component +def: "A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization." [PMID:11404334, PMID:8878678] +is_a: GO:0005721 ! pericentric heterochromatin +relationship: part_of GO:0005701 ! polytene chromosome chromocenter +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0005723 +name: alpha-heterochromatin +namespace: cellular_component +def: "A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization." [PMID:8878678] +is_a: GO:0005721 ! pericentric heterochromatin +relationship: part_of GO:0005701 ! polytene chromosome chromocenter +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0005724 +name: obsolete nuclear telomeric heterochromatin +namespace: cellular_component +def: "OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus." [GOC:ai] +comment: This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19086 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0005725 +name: intercalary heterochromatin +namespace: cellular_component +def: "Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes." [PMID:14579245] +is_a: GO:0005720 ! nuclear heterochromatin + +[Term] +id: GO:0005726 +name: perichromatin fibrils +namespace: cellular_component +def: "Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts." [PMID:14731598] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0005727 +name: extrachromosomal circular DNA +namespace: cellular_component +def: "Circular DNA structures that are not part of a chromosome." [GOC:ai] +subset: goslim_metagenomics +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0046821 ! extrachromosomal DNA + +[Term] +id: GO:0005728 +name: extrachromosomal rDNA circle +namespace: cellular_component +def: "Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats." [GOC:mah, PMID:12044934] +synonym: "extrachromosomal ribosomal DNA circle" EXACT [] +is_a: GO:0005727 ! extrachromosomal circular DNA + +[Term] +id: GO:0005729 +name: 2-micrometer circle DNA +namespace: cellular_component +def: "A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies." [PMID:12073320] +is_a: GO:0005727 ! extrachromosomal circular DNA + +[Term] +id: GO:0005730 +name: nucleolus +namespace: cellular_component +def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: NIF_Subcellular:sao1820400233 +xref: Wikipedia:Nucleolus +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0005731 +name: nucleolus organizer region +namespace: cellular_component +def: "A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed." [PMID:14504406] +synonym: "NOR" EXACT [] +synonym: "nucleolus organiser region" EXACT [] +synonym: "nucleolus organizer complex" RELATED [] +xref: Wikipedia:Nucleolus_organizer_region +is_a: GO:0030874 ! nucleolar chromatin + +[Term] +id: GO:0005732 +name: small nucleolar ribonucleoprotein complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type." [GOC:krc, GOC:mah, ISBN:0879695897] +comment: Note that 'nucleolar' in the term name is part of the RNA family designation 'small nucleolar', and does not necessarily reflect the location of the complex. +subset: goslim_pir +synonym: "small nucleolar ribonucleoprotein" EXACT [] +synonym: "snoRNP" EXACT [] +is_a: GO:1990904 ! ribonucleoprotein complex + +[Term] +id: GO:0005733 +name: obsolete small nucleolar RNA +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "small nucleolar RNA" EXACT [] +synonym: "snoRNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005734 +name: obsolete box C + D snoRNP protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "box C + D snoRNP protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005735 +name: obsolete box H + ACA snoRNP protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "box H + ACA snoRNP protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005736 +name: RNA polymerase I complex +namespace: cellular_component +def: "RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] +synonym: "DNA-directed RNA polymerase I activity" RELATED [] +synonym: "DNA-directed RNA polymerase I complex" EXACT [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0005737 +name: cytoplasm +namespace: cellular_component +def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: Wikipedia:Cytoplasm +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005739 +name: mitochondrion +namespace: cellular_component +def: "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [GOC:giardia, ISBN:0198506732] +comment: Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.) +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "mitochondria" EXACT [] +xref: NIF_Subcellular:sao1860313010 +xref: Wikipedia:Mitochondrion +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005740 +name: mitochondrial envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." [GOC:ai, GOC:pz] +subset: goslim_candida +subset: goslim_yeast +is_a: GO:0031967 ! organelle envelope +relationship: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0005741 +name: mitochondrial outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope." [GOC:ai] +synonym: "outer mitochondrial membrane" EXACT [] +xref: NIF_Subcellular:sao1289741256 +xref: Wikipedia:Outer_mitochondrial_membrane +is_a: GO:0031966 ! mitochondrial membrane +is_a: GO:0031968 ! organelle outer membrane + +[Term] +id: GO:0005742 +name: mitochondrial outer membrane translocase complex +namespace: cellular_component +def: "A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments." [PMID:12581629] +synonym: "GIP complex" NARROW [PMID:23201437] +synonym: "TOM complex" EXACT [PMID:23201437] +is_a: GO:0098799 ! outer mitochondrial membrane protein complex + +[Term] +id: GO:0005743 +name: mitochondrial inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae." [GOC:ai] +synonym: "inner mitochondrial membrane" EXACT [] +xref: NIF_Subcellular:sao1371347282 +xref: Wikipedia:Inner_mitochondrial_membrane +is_a: GO:0019866 ! organelle inner membrane +is_a: GO:0031966 ! mitochondrial membrane + +[Term] +id: GO:0005744 +name: TIM23 mitochondrial import inner membrane translocase complex +namespace: cellular_component +def: "The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor." [EC:7.4.2.3, PMID:27554484, PMID:8851659] +comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. +subset: goslim_pir +synonym: "mitochondrial inner membrane pre-sequence translocase complex" EXACT [] +synonym: "mitochondrial inner membrane presequence translocase complex" EXACT [] +synonym: "mitochondrial inner membrane translocase complex" BROAD [] +synonym: "Tim23 complex" EXACT [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex + +[Term] +id: GO:0005745 +name: m-AAA complex +namespace: cellular_component +def: "Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria." [GOC:mcc, PMID:12417197, PMID:21147776] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +is_a: GO:1905368 ! peptidase complex +relationship: part_of GO:0031305 ! integral component of mitochondrial inner membrane + +[Term] +id: GO:0005746 +name: mitochondrial respirasome +namespace: cellular_component +alt_id: GO:0097249 +def: "The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient." [GOC:curators, GOC:ecd, ISBN:0198547684] +synonym: "mitochondrial electron transport chain" EXACT [] +synonym: "mitochondrial respirasome" RELATED [] +synonym: "mitochondrial respiratory chain" EXACT [] +synonym: "mitochondrial respiratory chain supercomplex" EXACT [] +synonym: "mitochondrial respiratory supercomplex" EXACT [] +is_a: GO:0070469 ! respirasome +intersection_of: GO:0070469 ! respirasome +intersection_of: part_of GO:0005743 ! mitochondrial inner membrane +relationship: part_of GO:0005743 ! mitochondrial inner membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12846 xsd:anyURI +created_by: pr +creation_date: 2012-02-23T05:13:54Z + +[Term] +id: GO:0005747 +name: mitochondrial respiratory chain complex I +namespace: cellular_component +alt_id: GO:0005748 +def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone." [GOC:mtg_sensu, ISBN:0198547684] +is_a: GO:0045271 ! respiratory chain complex I +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045271 ! respiratory chain complex I +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005746 ! mitochondrial respirasome +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4930 + +[Term] +id: GO:0005749 +name: mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) +namespace: cellular_component +alt_id: GO:0008136 +alt_id: GO:0009362 +alt_id: GO:0019738 +alt_id: GO:0030390 +def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain." [GOC:mtg_sensu, GOC:vw, ISBN:0198547684] +synonym: "mitochondrial fumarate reductase complex" EXACT [] +is_a: GO:0045257 ! succinate dehydrogenase complex (ubiquinone) +is_a: GO:0045283 ! fumarate reductase complex +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045283 ! fumarate reductase complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005746 ! mitochondrial respirasome + +[Term] +id: GO:0005750 +name: mitochondrial respiratory chain complex III +namespace: cellular_component +alt_id: GO:0015008 +def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1." [GOC:mtg_sensu, ISBN:0198547684] +synonym: "mitochondrial coenzyme Q-cytochrome c oxidoreductase complex" EXACT [] +synonym: "mitochondrial coenzyme Q-cytochrome c reductase complex" EXACT [] +synonym: "mitochondrial complex III" EXACT [GOC:mcc] +synonym: "mitochondrial cytochrome bc(1) complex" EXACT [GOC:mcc] +synonym: "mitochondrial cytochrome bc1 complex" EXACT [GOC:mcc] +synonym: "mitochondrial electron transport complex III" RELATED [GOC:mcc] +synonym: "mitochondrial ubiquinol-cytochrome c oxidoreductase complex" EXACT [GOC:mcc] +synonym: "mitochondrial ubiquinol-cytochrome-c reductase complex" EXACT [GOC:mcc] +is_a: GO:0045275 ! respiratory chain complex III +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045275 ! respiratory chain complex III +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005746 ! mitochondrial respirasome + +[Term] +id: GO:0005751 +name: mitochondrial respiratory chain complex IV +namespace: cellular_component +alt_id: GO:0005752 +def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2)." [GOC:mtg_sensu, ISBN:0198547684] +is_a: GO:0045277 ! respiratory chain complex IV +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045277 ! respiratory chain complex IV +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005746 ! mitochondrial respirasome + +[Term] +id: GO:0005753 +name: mitochondrial proton-transporting ATP synthase complex +namespace: cellular_component +alt_id: GO:0016470 +def: "A proton-transporting ATP synthase complex found in the mitochondrial membrane." [GOC:mah, GOC:mtg_sensu] +synonym: "mitochondrial respiratory chain complex V" EXACT [] +is_a: GO:0045259 ! proton-transporting ATP synthase complex +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045259 ! proton-transporting ATP synthase complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0005754 +name: mitochondrial proton-transporting ATP synthase, catalytic core +namespace: cellular_component +def: "The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase." [GOC:mtg_sensu, PMID:10838056] +is_a: GO:0045267 ! proton-transporting ATP synthase, catalytic core +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045267 ! proton-transporting ATP synthase, catalytic core +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0000275 ! mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) + +[Term] +id: GO:0005755 +name: obsolete hydrogen-transporting ATP synthase, coupling factor CF(0) +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "hydrogen-transporting ATP synthase, coupling factor CF(0)" EXACT [] +is_obsolete: true +consider: GO:0045263 + +[Term] +id: GO:0005756 +name: mitochondrial proton-transporting ATP synthase, central stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis." [GOC:mtg_sensu, PMID:10838056] +is_a: GO:0045269 ! proton-transporting ATP synthase, central stalk +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +intersection_of: GO:0045269 ! proton-transporting ATP synthase, central stalk +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0000275 ! mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) + +[Term] +id: GO:0005757 +name: mitochondrial permeability transition pore complex +namespace: cellular_component +def: "A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D)." [PMID:10393078] +synonym: "mitochondrial PT pore complex" EXACT [] +synonym: "MPTP complex" EXACT [] +synonym: "PTPC" BROAD [PMID:21760595] +is_a: GO:0046930 ! pore complex +is_a: GO:0098798 ! mitochondrial protein complex +relationship: part_of GO:0005740 ! mitochondrial envelope + +[Term] +id: GO:0005758 +name: mitochondrial intermembrane space +namespace: cellular_component +alt_id: GO:0031971 +def: "The region between the inner and outer lipid bilayers of the mitochondrial envelope." [GOC:mah] +synonym: "mitochondrial envelope lumen" EXACT [] +synonym: "mitochondrial membrane lumen" RELATED [] +xref: NIF_Subcellular:sao118944228 +is_a: GO:0031970 ! organelle envelope lumen +relationship: part_of GO:0005740 ! mitochondrial envelope + +[Term] +id: GO:0005759 +name: mitochondrial matrix +namespace: cellular_component +alt_id: GO:0031980 +def: "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation." [GOC:as, ISBN:0198506732] +synonym: "mitochondrial lumen" EXACT [] +synonym: "mitochondrial stroma" NARROW [] +xref: NIF_Subcellular:sao1804523077 +xref: Wikipedia:Mitochondrial_matrix +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0005760 +name: gamma DNA polymerase complex +namespace: cellular_component +def: "A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA." [GOC:jl, PMID:12045093] +is_a: GO:0042575 ! DNA polymerase complex +is_a: GO:0098798 ! mitochondrial protein complex +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0005761 +name: mitochondrial ribosome +namespace: cellular_component +def: "A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes." [GOC:mah, ISBN:0198506732] +synonym: "55S ribosome, mitochondrial" NARROW [] +is_a: GO:0000313 ! organellar ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0005762 +name: mitochondrial large ribosomal subunit +namespace: cellular_component +def: "The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] +synonym: "39S ribosomal subunit, mitochondrial" NARROW [] +is_a: GO:0000315 ! organellar large ribosomal subunit +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0015934 ! large ribosomal subunit +intersection_of: part_of GO:0005761 ! mitochondrial ribosome +relationship: part_of GO:0005761 ! mitochondrial ribosome + +[Term] +id: GO:0005763 +name: mitochondrial small ribosomal subunit +namespace: cellular_component +def: "The smaller of the two subunits of a mitochondrial ribosome." [GOC:mcc] +synonym: "28S ribosomal subunit, mitochondrial" NARROW [] +synonym: "mitochondrial ribosomal small subunit complex" EXACT [] +synonym: "mitochondrial ribosomal SSU complex" EXACT [] +is_a: GO:0000314 ! organellar small ribosomal subunit +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0015935 ! small ribosomal subunit +intersection_of: part_of GO:0005761 ! mitochondrial ribosome +relationship: part_of GO:0005761 ! mitochondrial ribosome + +[Term] +id: GO:0005764 +name: lysosome +namespace: cellular_component +def: "A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." [GOC:mah, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +xref: NIF_Subcellular:sao585356902 +xref: Wikipedia:Lysosome +is_a: GO:0000323 ! lytic vacuole + +[Term] +id: GO:0005765 +name: lysosomal membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." [GOC:ai] +synonym: "lysosome membrane" EXACT [] +is_a: GO:0098852 ! lytic vacuole membrane +relationship: part_of GO:0005764 ! lysosome + +[Term] +id: GO:0005766 +name: primary lysosome +namespace: cellular_component +def: "A lysosome before it has fused with a vesicle or vacuole." [GOC:jl, ISBN:0815316194] +xref: NIF_Subcellular:sao1140587416 +is_a: GO:0005764 ! lysosome + +[Term] +id: GO:0005767 +name: secondary lysosome +namespace: cellular_component +def: "Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome." [GOC:jl, ISBN:0815316194] +xref: NIF_Subcellular:sao1549842807 +is_a: GO:0005764 ! lysosome + +[Term] +id: GO:0005768 +name: endosome +namespace: cellular_component +def: "A vacuole to which materials ingested by endocytosis are delivered." [ISBN:0198506732, PMID:19696797] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +xref: NIF_Subcellular:sao1720343330 +xref: Wikipedia:Endosome +is_a: GO:0031410 ! cytoplasmic vesicle +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0005769 +name: early endosome +namespace: cellular_component +def: "A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways." [GOC:mah, NIF_Subcellular:nlx_subcell_20090701, PMID:19696797] +xref: NIF_Subcellular:nlx_subcell_20090701 +is_a: GO:0005768 ! endosome + +[Term] +id: GO:0005770 +name: late endosome +namespace: cellular_component +def: "A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." [NIF_Subcellular:nlx_subcell_20090702, PMID:11964142, PMID:2557062] +synonym: "prevacuolar compartment" EXACT [] +synonym: "PVC" BROAD [] +xref: NIF_Subcellular:nlx_subcell_20090702 +is_a: GO:0005768 ! endosome + +[Term] +id: GO:0005771 +name: multivesicular body +namespace: cellular_component +def: "A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm." [PMID:11566881, PMID:16533950] +synonym: "multivesicular endosome" EXACT [PMID:12122203] +synonym: "MVB" EXACT [] +synonym: "MVE" EXACT [PMID:12122203] +xref: NIF_Subcellular:sao2045955158 +is_a: GO:0005770 ! late endosome + +[Term] +id: GO:0005773 +name: vacuole +namespace: cellular_component +def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "vacuolar carboxypeptidase Y" RELATED [] +xref: Wikipedia:Vacuole +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005774 +name: vacuolar membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0005773 ! vacuole + +[Term] +id: GO:0005775 +name: vacuolar lumen +namespace: cellular_component +def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0005773 ! vacuole +relationship: part_of GO:0005773 ! vacuole + +[Term] +id: GO:0005776 +name: autophagosome +namespace: cellular_component +def: "A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy." [GOC:autophagy, ISBN:0198547684, PMID:11099404] +synonym: "autophagic vacuole" EXACT [NIF_Subcellular:sao8663416959] +synonym: "initial autophagic vacuole" RELATED [NIF_Subcellular:sao8663416959] +xref: NIF_Subcellular:sao8663416959 +is_a: GO:0005773 ! vacuole + +[Term] +id: GO:0005777 +name: peroxisome +namespace: cellular_component +alt_id: GO:0019818 +def: "A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism." [GOC:pm, PMID:9302272, UniProtKB-KW:KW-0576] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_plant +subset: goslim_yeast +synonym: "peroxisomal" RELATED [] +synonym: "peroxisome vesicle" BROAD [] +xref: NIF_Subcellular:sao499555322 +xref: Wikipedia:Peroxisome +is_a: GO:0042579 ! microbody + +[Term] +id: GO:0005778 +name: peroxisomal membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a peroxisome." [GOC:mah] +synonym: "peroxisome membrane" EXACT [] +is_a: GO:0031903 ! microbody membrane +relationship: part_of GO:0005777 ! peroxisome + +[Term] +id: GO:0005779 +name: integral component of peroxisomal membrane +namespace: cellular_component +def: "The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:mah] +synonym: "integral to peroxisomal membrane" NARROW [] +is_a: GO:0031231 ! intrinsic component of peroxisomal membrane +is_a: GO:0031301 ! integral component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005778 ! peroxisomal membrane + +[Term] +id: GO:0005780 +name: extrinsic component of intraperoxisomal membrane +namespace: cellular_component +def: "The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:jl, GOC:mah] +synonym: "extrinsic to intraperoxisomal membrane" EXACT [] +synonym: "intra-peroxisomal peripheral membrane" RELATED [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005778 ! peroxisomal membrane +relationship: part_of GO:0005778 ! peroxisomal membrane + +[Term] +id: GO:0005781 +name: obsolete peroxisome targeting signal receptor complex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric. +synonym: "peroxisome targeting signal receptor complex" EXACT [] +is_obsolete: true +consider: GO:0000268 +consider: GO:0006625 + +[Term] +id: GO:0005782 +name: peroxisomal matrix +namespace: cellular_component +alt_id: GO:0031909 +def: "The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase." [GOC:curators, ISBN:0815316194] +synonym: "peroxisomal lumen" EXACT [] +is_a: GO:0031907 ! microbody lumen +relationship: part_of GO:0005777 ! peroxisome + +[Term] +id: GO:0005783 +name: endoplasmic reticulum +namespace: cellular_component +def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." [ISBN:0198506732] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "ER" EXACT [] +xref: NIF_Subcellular:sao1036339110 +xref: Wikipedia:Endoplasmic_reticulum +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0005784 +name: Sec61 translocon complex +namespace: cellular_component +def: "A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events." [GOC:mah, PMID:18166647] +synonym: "Sec61p-Sbh1p-Sss1p complex" NARROW [GOC:mah] +is_a: GO:0071256 ! translocon complex + +[Term] +id: GO:0005785 +name: signal recognition particle receptor complex +namespace: cellular_component +def: "A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex." [ISBN:0198506732] +synonym: "docking protein complex" RELATED [] +synonym: "SR complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030867 ! rough endoplasmic reticulum membrane + +[Term] +id: GO:0005786 +name: signal recognition particle, endoplasmic reticulum targeting +namespace: cellular_component +alt_id: GO:0005855 +def: "A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0198506732] +synonym: "signal sequence receptor complex" EXACT [] +synonym: "SRP" EXACT [] +xref: Wikipedia:Signal_recognition_particle +is_a: GO:0048500 ! signal recognition particle + +[Term] +id: GO:0005787 +name: signal peptidase complex +namespace: cellular_component +def: "A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space." [GOC:sgd_curators, PMID:1846444, PMID:7615509] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1905368 ! peptidase complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0005788 +name: endoplasmic reticulum lumen +namespace: cellular_component +alt_id: GO:0016022 +def: "The volume enclosed by the membranes of the endoplasmic reticulum." [ISBN:0198547684] +synonym: "cisternal lumen" EXACT [] +synonym: "endoplasmic reticulum cisterna" EXACT [] +synonym: "ER cisterna" EXACT [] +synonym: "ER lumen" EXACT [] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0005789 +name: endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the endoplasmic reticulum." [GOC:mah] +synonym: "ER membrane" EXACT [] +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network + +[Term] +id: GO:0005790 +name: smooth endoplasmic reticulum +namespace: cellular_component +def: "The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER." [ISBN:0198506732] +synonym: "SER" EXACT [] +synonym: "smooth ER" EXACT [] +xref: NIF_Subcellular:sao710427438 +xref: Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum +is_a: GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0005791 +name: rough endoplasmic reticulum +namespace: cellular_component +def: "The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae." [ISBN:0198506732] +synonym: "RER" EXACT [] +synonym: "rough ER" EXACT [] +xref: NIF_Subcellular:sao1881364067 +xref: Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum +is_a: GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0005792 +name: obsolete microsome +namespace: cellular_component +def: "OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g." [ISBN:0198506732] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "microsomal membrane" RELATED [] +synonym: "microsome" EXACT [] +xref: Wikipedia:Microsome +is_obsolete: true +consider: GO:0043231 + +[Term] +id: GO:0005793 +name: endoplasmic reticulum-Golgi intermediate compartment +namespace: cellular_component +def: "A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport." [GOC:pr, PMID:16723730] +synonym: "EGTC" EXACT [] +synonym: "endoplasmic reticulum-Golgi transport container" EXACT [] +synonym: "ER-Golgi intermediate compartment" EXACT [] +synonym: "ER-Golgi transport container" EXACT [] +synonym: "ERGIC" EXACT [] +synonym: "pre-Golgi intermediate compartment" EXACT [] +synonym: "vesicular-tubular cluster" EXACT [Wikipedia:Vesicular-tubular_cluster] +synonym: "VTC" EXACT [] +xref: Wikipedia:Vesicular-tubular_cluster +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005794 +name: Golgi apparatus +namespace: cellular_component +def: "A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions." [ISBN:0198506732] +comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "Golgi" BROAD [] +synonym: "Golgi complex" EXACT [] +synonym: "Golgi ribbon" NARROW [] +xref: NIF_Subcellular:sao451912436 +xref: Wikipedia:Golgi_apparatus +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0005795 +name: Golgi stack +namespace: cellular_component +alt_id: GO:0016940 +def: "The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack." [GOC:mah, ISBN:0815316194] +synonym: "dictyosome" NARROW [] +synonym: "Golgi cisternae" EXACT [] +is_a: GO:0098791 ! Golgi apparatus subcompartment + +[Term] +id: GO:0005796 +name: Golgi lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks." [GOC:mah] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0005797 +name: Golgi medial cisterna +namespace: cellular_component +def: "The middle Golgi cisterna (or cisternae)." [ISBN:0815316194] +is_a: GO:0031985 ! Golgi cisterna + +[Term] +id: GO:0005798 +name: Golgi-associated vesicle +namespace: cellular_component +def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] +comment: Note that this definition includes vesicles that are transiently associated with the Golgi. +synonym: "Golgi vesicle" RELATED [] +synonym: "vesicular component" RELATED [NIF_Subcellular:sao138219748] +xref: NIF_Subcellular:sao819927218 +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0005799 +name: obsolete coatomer +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because its position and synonym implied that it confused a coated vesicle with the coat itself. +synonym: "coatomer" EXACT [] +synonym: "COPI vesicle" RELATED [] +is_obsolete: true +consider: GO:0030126 +consider: GO:0030137 + +[Term] +id: GO:0005800 +name: obsolete COPII vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. +synonym: "COPII vesicle" EXACT [] +is_obsolete: true +consider: GO:0030134 + +[Term] +id: GO:0005801 +name: cis-Golgi network +namespace: cellular_component +def: "The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum." [ISBN:0198506732, ISBN:0815316194] +comment: The CGN is not considered part of the Golgi apparatus but is a separate organelle. +synonym: "cis face" BROAD [NIF_Subcellular:sao632188024] +synonym: "cis Golgi network" EXACT [] +synonym: "forming face" RELATED [] +synonym: "Golgi cis face" RELATED [] +synonym: "Golgi cis-face" RELATED [] +xref: NIF_Subcellular:sao632188024 +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0005802 +name: trans-Golgi network +namespace: cellular_component +def: "The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination." [GOC:vw, ISBN:0815316194] +comment: There are different opinions about whether the TGN should be considered part of the Golgi apparatus or not. We follow Alberts et al, 1994 (ISBN:0815316194), who consider it to be a part. +synonym: "Golgi trans face" RELATED [] +synonym: "Golgi trans-face" RELATED [] +synonym: "late Golgi" RELATED [GOC:mah] +synonym: "maturing face" RELATED [] +synonym: "TGN" EXACT [] +synonym: "trans face" BROAD [NIF_Subcellular:sao1039242387] +synonym: "trans Golgi network" EXACT [] +xref: NIF_Subcellular:sao9456487 +is_a: GO:0098791 ! Golgi apparatus subcompartment + +[Term] +id: GO:0005803 +name: obsolete secretory vesicle +namespace: cellular_component +def: "OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [ISBN:0198547684] +comment: This term was made obsolete because it was being used to describe two different components. +synonym: "secretory vesicle" EXACT [] +synonym: "transition vesicle" NARROW [] +is_obsolete: true +consider: GO:0030133 +consider: GO:0030141 + +[Term] +id: GO:0005804 +name: obsolete secretory vesicle membrane +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because its parent was made obsolete. +synonym: "secretory vesicle membrane" EXACT [] +is_obsolete: true +consider: GO:0030658 +consider: GO:0030667 + +[Term] +id: GO:0005805 +name: obsolete ER-Golgi transport vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. +synonym: "ER-Golgi transport vesicle" EXACT [] +is_obsolete: true +consider: GO:0030134 + +[Term] +id: GO:0005806 +name: obsolete Golgi-ER transport vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. +synonym: "Golgi-ER transport vesicle" EXACT [] +is_obsolete: true +consider: GO:0030142 + +[Term] +id: GO:0005808 +name: obsolete Golgi-plasma membrane transport vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles. +synonym: "Golgi-plasma membrane transport vesicle" EXACT [] +is_obsolete: true +consider: GO:0030133 + +[Term] +id: GO:0005809 +name: obsolete Golgi-vacuole transport vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. +synonym: "Golgi-vacuole transport vesicle" EXACT [] +is_obsolete: true +consider: GO:0030133 + +[Term] +id: GO:0005810 +name: obsolete endocytotic transport vesicle +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. +synonym: "endocytotic transport vesicle" EXACT [] +is_obsolete: true +replaced_by: GO:0030139 + +[Term] +id: GO:0005811 +name: lipid droplet +namespace: cellular_component +def: "An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins." [GOC:mah, GOC:tb] +comment: Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers. +subset: goslim_chembl +subset: goslim_generic +synonym: "adiposome" EXACT [] +synonym: "lipid body" EXACT [] +synonym: "lipid particle" EXACT [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0005813 +name: centrosome +namespace: cellular_component +def: "A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." [GOC:mah, ISBN:0198547684] +subset: goslim_pir +xref: Wikipedia:Centrosome +is_a: GO:0005815 ! microtubule organizing center +relationship: has_part GO:0005814 ! centriole +property_value: RO:0002161 NCBITaxon:27896 +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0005814 +name: centriole +namespace: cellular_component +def: "A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle." [ISBN:0198547684] +comment: In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. +synonym: "daughter centriole" NARROW [GOC:cilia] +synonym: "mother centriole" NARROW [GOC:cilia] +xref: NIF_Subcellular:sao95019936 +xref: Wikipedia:Centriole +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005815 ! microtubule organizing center + +[Term] +id: GO:0005815 +name: microtubule organizing center +namespace: cellular_component +def: "An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides." [GOC:vw, ISBN:0815316194, PMID:17072892, PMID:17245416, Wikipedia:Microtubule_organizing_center] +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "microtubule organising centre" EXACT [] +synonym: "MTOC" EXACT [] +xref: Wikipedia:Microtubule_organizing_center +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0005816 +name: spindle pole body +namespace: cellular_component +def: "The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome." [ISBN:0879693568] +synonym: "SPB" EXACT [GOC:mah] +xref: Wikipedia:Spindle_pole_body +is_a: GO:0005815 ! microtubule organizing center + +[Term] +id: GO:0005817 +name: obsolete centrosomal mitotic factor +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:clt] +comment: This term was made obsolete because it was not defined. +synonym: "centrosomal mitotic factor" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005818 +name: aster +namespace: cellular_component +def: "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." [GOC:clt] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +is_a: GO:0099080 ! supramolecular complex +relationship: part_of GO:0005819 ! spindle + +[Term] +id: GO:0005819 +name: spindle +namespace: cellular_component +def: "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." [ISBN:0198547684] +xref: Wikipedia:Spindle_apparatus +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0005821 +name: intermediate layer of spindle pole body +namespace: cellular_component +def: "Structure between the central and outer plaques of the spindle pole body." [PMID:9215630] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0005822 +name: inner plaque of spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0005823 +name: central plaque of spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0005824 +name: outer plaque of spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0005825 +name: half bridge of spindle pole body +namespace: cellular_component +def: "Structure adjacent to the plaques of the spindle pole body." [ISBN:0879693568] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0005826 +name: actomyosin contractile ring +namespace: cellular_component +alt_id: GO:0030480 +def: "A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis." [GOC:expert_jrp, GOC:sgd_curators, GOC:vw, ISBN:0805319409, ISBN:0815316194, PMID:28914606] +synonym: "actomyosin ring" RELATED [] +synonym: "CAR" EXACT [] +synonym: "constriction ring" RELATED [] +synonym: "contractile actomyosin ring" EXACT [] +synonym: "cytokinetic ring" RELATED [] +is_a: GO:0070938 ! contractile ring +relationship: part_of GO:0030864 ! cortical actin cytoskeleton +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0005827 +name: polar microtubule +namespace: cellular_component +def: "Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart." [ISBN:0815316194] +synonym: "pole-to-pole microtubule" EXACT [] +is_a: GO:0005876 ! spindle microtubule +intersection_of: GO:0005876 ! spindle microtubule +intersection_of: part_of GO:0000922 ! spindle pole +relationship: part_of GO:0000922 ! spindle pole + +[Term] +id: GO:0005828 +name: kinetochore microtubule +namespace: cellular_component +def: "Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation." [ISBN:0815316194] +synonym: "pole-to-kinetochore microtubule" EXACT [] +is_a: GO:0005876 ! spindle microtubule + +[Term] +id: GO:0005829 +name: cytosol +namespace: cellular_component +def: "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hjd, GOC:jl] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant +xref: NIF_Subcellular:sao101633890 +xref: Wikipedia:Cytosol +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005831 +name: steroid hormone aporeceptor complex +namespace: cellular_component +def: "A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand." [PMID:7493981] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005832 +name: chaperonin-containing T-complex +namespace: cellular_component +def: "A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor." [GOC:sgd_curators, PMID:11580267] +synonym: "CCT particle" EXACT [] +synonym: "TriC" EXACT [] +is_a: GO:0101031 ! chaperone complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005833 +name: hemoglobin complex +namespace: cellular_component +def: "An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group." [GOC:jl, ISBN:0198506732] +synonym: "haemoglobin complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005834 +name: heterotrimeric G-protein complex +namespace: cellular_component +def: "Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein." [ISBN:0198547684] +comment: See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'. +synonym: "heterotrimeric G-protein GTPase activity" RELATED [] +synonym: "heterotrimeric G-protein GTPase, alpha-subunit" NARROW [] +synonym: "heterotrimeric G-protein GTPase, beta-subunit" NARROW [] +synonym: "heterotrimeric G-protein GTPase, gamma-subunit" NARROW [] +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1905360 ! GTPase complex +relationship: part_of GO:0031234 ! extrinsic component of cytoplasmic side of plasma membrane + +[Term] +id: GO:0005835 +name: fatty acid synthase complex +namespace: cellular_component +alt_id: GO:0031373 +alt_id: GO:0031374 +def: "A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA." [GOC:pde, GOC:sgd_curators, ISBN:0716746840] +subset: goslim_pir +synonym: "cytosolic FAS complex" EXACT [] +synonym: "cytosolic fatty acid synthase complex" EXACT [] +synonym: "cytosolic type I FAS complex" EXACT [] +synonym: "cytosolic type I fatty acid synthase complex" EXACT [] +synonym: "FAS complex" EXACT [] +synonym: "fatty acid synthetase complex" EXACT [] +synonym: "holo-[acyl-carrier-protein] synthase complex" RELATED [] +xref: Wikipedia:Fatty_acid_synthetase_complex +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005836 +name: fatty-acyl-CoA synthase complex +namespace: cellular_component +def: "A protein complex that possesses fatty-acyl-CoA synthase activity." [BRENDA:2.3.1.86, GOC:mah] +comment: Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes. +synonym: "fatty acyl CoA synthase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005837 +name: obsolete 26S proteasome +namespace: cellular_component +def: "OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome." [PMID:10410804] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "26S proteasome" EXACT [] +is_obsolete: true +consider: GO:0000502 + +[Term] +id: GO:0005838 +name: proteasome regulatory particle +namespace: cellular_component +def: "A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex." [GOC:mtg_sensu, GOC:rb] +synonym: "19S regulatory particle" NARROW [] +synonym: "modulator complex" RELATED [CORUM:28] +synonym: "PA700 proteasome activator" NARROW [] +synonym: "PA700-dependent proteasome activator" EXACT [CORUM:28] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0022624 ! proteasome accessory complex + +[Term] +id: GO:0005839 +name: proteasome core complex +namespace: cellular_component +alt_id: GO:0000503 +def: "A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex." [GOC:rb, PMID:10806206] +subset: goslim_metagenomics +synonym: "20S core complex" NARROW [] +synonym: "20S proteasome" NARROW [GOC:cjk] +synonym: "macropain" EXACT [] +synonym: "PA28gamma-20S proteasome" NARROW [CORUM:194] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000502 ! proteasome complex + +[Term] +id: GO:0005840 +name: ribosome +namespace: cellular_component +alt_id: GO:0033279 +def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] +synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] +synonym: "ribosomal RNA" RELATED [] +xref: NIF_Subcellular:sao1429207766 +xref: Wikipedia:Ribosome +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0005844 +name: polysome +namespace: cellular_component +def: "A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro." [ISBN:0198506732, NIF_Subcellular:sao1038025871] +subset: goslim_pir +synonym: "polyribosome" EXACT [NIF_Subcellular:sao1038025871] +xref: NIF_Subcellular:sao1038025871 +xref: Wikipedia:Polysome +is_a: GO:1990904 ! ribonucleoprotein complex + +[Term] +id: GO:0005845 +name: mRNA cap binding complex +namespace: cellular_component +def: "Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA." [GOC:jid] +synonym: "mRNA cap complex" RELATED [] +is_a: GO:0034518 ! RNA cap binding complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005846 +name: nuclear cap binding complex +namespace: cellular_component +def: "A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export." [PMID:16043498] +comment: Note that this complex can be found in the cytoplasm as well as the nucleus. +synonym: "CBC" RELATED [] +synonym: "mRNA cap binding complex" NARROW [] +synonym: "NCBP-NIP1 complex" NARROW [] +synonym: "snRNA cap binding complex" NARROW [] +is_a: GO:0034518 ! RNA cap binding complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005847 +name: mRNA cleavage and polyadenylation specificity factor complex +namespace: cellular_component +def: "A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal." [PMID:14749727] +synonym: "CFII complex" RELATED [] +synonym: "cleavage and polyadenylylation specificity factor activity" RELATED [] +synonym: "CPF complex" NARROW [] +synonym: "CPSF complex" NARROW [] +is_a: GO:0005849 ! mRNA cleavage factor complex + +[Term] +id: GO:0005848 +name: mRNA cleavage stimulating factor complex +namespace: cellular_component +def: "A protein complex required for mRNA cleavage but not for poly(A) addition." [GOC:mah, PMID:10357856] +synonym: "cleavage stimulation factor activity" RELATED [] +synonym: "CstF complex" NARROW [] +is_a: GO:0005849 ! mRNA cleavage factor complex + +[Term] +id: GO:0005849 +name: mRNA cleavage factor complex +namespace: cellular_component +def: "Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules." [GOC:mah, PMID:10357856] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0005850 +name: eukaryotic translation initiation factor 2 complex +namespace: cellular_component +def: "Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA." [PMID:10216940] +synonym: "eIF-2" EXACT [] +synonym: "eIF2" EXACT [GOC:mah] +xref: Wikipedia:EIF-2 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005851 +name: eukaryotic translation initiation factor 2B complex +namespace: cellular_component +def: "A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon." [PMID:9438375] +synonym: "eIF-2B" EXACT [] +synonym: "eif2B" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005852 +name: eukaryotic translation initiation factor 3 complex +namespace: cellular_component +def: "A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532] +synonym: "eIF-3" EXACT [] +synonym: "eIF3" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005853 +name: eukaryotic translation elongation factor 1 complex +namespace: cellular_component +def: "A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma." [GOC:jl, PMID:10216950] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005854 +name: nascent polypeptide-associated complex +namespace: cellular_component +def: "A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome." [PMID:12475173, PMID:7568149] +synonym: "NAC" EXACT [] +synonym: "NACA" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005856 +name: cytoskeleton +namespace: cellular_component +def: "Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, ISBN:0198547684, PMID:16959967] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: Wikipedia:Cytoskeleton +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0005858 +name: axonemal dynein complex +namespace: cellular_component +def: "A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion." [GOC:cilia, GOC:hla, GOC:krc, ISBN:0815316194] +synonym: "axonemal dynein heavy chain" NARROW [] +synonym: "axonemal dynein intermediate chain" NARROW [] +synonym: "axonemal dynein intermediate light chain" NARROW [] +synonym: "axonemal dynein light chain" NARROW [] +is_a: GO:0030286 ! dynein complex +intersection_of: GO:0030286 ! dynein complex +intersection_of: part_of GO:0005930 ! axoneme +relationship: part_of GO:0005930 ! axoneme + +[Term] +id: GO:0005859 +name: muscle myosin complex +namespace: cellular_component +def: "A filament of myosin found in a muscle cell of any type." [GOC:mah] +is_a: GO:0016460 ! myosin II complex +intersection_of: GO:0016460 ! myosin II complex +intersection_of: part_of GO:0043292 ! contractile fiber +relationship: part_of GO:0043292 ! contractile fiber + +[Term] +id: GO:0005861 +name: troponin complex +namespace: cellular_component +def: "A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction." [ISBN:0815316194] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005865 ! striated muscle thin filament + +[Term] +id: GO:0005862 +name: muscle thin filament tropomyosin +namespace: cellular_component +def: "A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments." [ISBN:0815316194] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005865 ! striated muscle thin filament + +[Term] +id: GO:0005863 +name: striated muscle myosin thick filament +namespace: cellular_component +def: "Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils." [GOC:mtg_muscle, ISBN:0815316194] +is_a: GO:0032982 ! myosin filament +is_a: GO:0036379 ! myofilament +relationship: has_part GO:0005859 ! muscle myosin complex +relationship: part_of GO:0030017 ! sarcomere + +[Term] +id: GO:0005865 +name: striated muscle thin filament +namespace: cellular_component +def: "Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils." [ISBN:0815316194] +is_a: GO:0036379 ! myofilament +relationship: part_of GO:0015629 ! actin cytoskeleton +relationship: part_of GO:0030017 ! sarcomere + +[Term] +id: GO:0005868 +name: cytoplasmic dynein complex +namespace: cellular_component +def: "Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains." [GOC:cilia, GOC:hla, GOC:krc, GOC:mah, PMID:12600311] +comment: Note that this term is labelled based on phylogenetic classification and community usage, rather than strict cellular localization. Cytoplasmic dynein complexes may contain ciliary dyneins; therefore the term is not linked to 'cytoplasm'. Cytoplasmic dynein complexes do not contain axonemal dyneins; see GO:0005858 axonemal dynein complex. +synonym: "cytoplasmic dynein heavy chain" NARROW [] +synonym: "cytoplasmic dynein intermediate chain" NARROW [] +synonym: "cytoplasmic dynein intermediate light chain" NARROW [] +synonym: "cytoplasmic dynein light chain" NARROW [] +is_a: GO:0030286 ! dynein complex + +[Term] +id: GO:0005869 +name: dynactin complex +namespace: cellular_component +def: "A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach." [ISBN:0198506732] +is_a: GO:0005875 ! microtubule associated complex +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0005870 +name: actin capping protein of dynactin complex +namespace: cellular_component +def: "A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex." [GOC:jl, PMID:18221362, PMID:18544499] +is_a: GO:0008290 ! F-actin capping protein complex +intersection_of: GO:0008290 ! F-actin capping protein complex +intersection_of: part_of GO:0005869 ! dynactin complex +relationship: part_of GO:0005869 ! dynactin complex + +[Term] +id: GO:0005871 +name: kinesin complex +namespace: cellular_component +def: "Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work." [GOC:mah, http://www.proweb.org/kinesin//KinesinMotility.html, http://www.proweb.org/kinesin//KinesinStructure.html] +is_a: GO:0005875 ! microtubule associated complex + +[Term] +id: GO:0005872 +name: minus-end kinesin complex +namespace: cellular_component +def: "Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule." [GOC:mah] +is_a: GO:0005871 ! kinesin complex + +[Term] +id: GO:0005873 +name: plus-end kinesin complex +namespace: cellular_component +def: "Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule." [GOC:mah] +is_a: GO:0005871 ! kinesin complex + +[Term] +id: GO:0005874 +name: microtubule +namespace: cellular_component +def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] +subset: goslim_metagenomics +synonym: "microtubuli" EXACT [] +synonym: "microtubulus" EXACT [] +synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196] +xref: NIF_Subcellular:sao1846835077 +xref: Wikipedia:Microtubule +is_a: GO:0099513 ! polymeric cytoskeletal fiber +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0005875 +name: microtubule associated complex +namespace: cellular_component +def: "Any multimeric complex connected to a microtubule." [GOC:jl] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0005876 +name: spindle microtubule +namespace: cellular_component +def: "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." [ISBN:0815316194] +is_a: GO:0005874 ! microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:0005819 ! spindle +relationship: part_of GO:0005819 ! spindle + +[Term] +id: GO:0005879 +name: axonemal microtubule +namespace: cellular_component +def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194] +is_a: GO:0005881 ! cytoplasmic microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:0005930 ! axoneme +relationship: part_of GO:0005930 ! axoneme + +[Term] +id: GO:0005880 +name: nuclear microtubule +namespace: cellular_component +def: "Any microtubule in the nucleus of a cell." [GOC:mah] +is_a: GO:0005874 ! microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0005881 +name: cytoplasmic microtubule +namespace: cellular_component +def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] +synonym: "non-spindle-associated astral microtubule" NARROW [] +is_a: GO:0005874 ! microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005882 +name: intermediate filament +namespace: cellular_component +def: "A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins." [http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm, ISBN:0198506732] +synonym: "intermediate filament associated protein" RELATED [] +synonym: "type I intermediate filament associated protein" RELATED [] +synonym: "type II intermediate filament associated protein" RELATED [] +xref: FMA:63851 +xref: NIF_Subcellular:sao952483289 +xref: Wikipedia:Intermediate_filament +is_a: GO:0099513 ! polymeric cytoskeletal fiber +relationship: part_of GO:0045111 ! intermediate filament cytoskeleton + +[Term] +id: GO:0005883 +name: neurofilament +namespace: cellular_component +def: "A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter." [ISBN:0198506732, ISBN:0716731363, ISBN:0815316194] +synonym: "type IV intermediate filament" EXACT [] +xref: NIF_Subcellular:sao1316272517 +xref: Wikipedia:Neurofilament +is_a: GO:0005882 ! intermediate filament +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005884 +name: actin filament +namespace: cellular_component +def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] +synonym: "microfilament" EXACT [] +xref: FMA:63850 +xref: NIF_Subcellular:sao1588493326 +xref: Wikipedia:Actin +is_a: GO:0099513 ! polymeric cytoskeletal fiber +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0005885 +name: Arp2/3 protein complex +namespace: cellular_component +def: "A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments." [GOC:jl, GOC:vw, PMID:12479800] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0005886 +name: plasma membrane +namespace: cellular_component +alt_id: GO:0005904 +def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_plant +subset: goslim_yeast +synonym: "bacterial inner membrane" NARROW [] +synonym: "cell membrane" EXACT [] +synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] +synonym: "cytoplasmic membrane" EXACT [] +synonym: "inner endospore membrane" NARROW [] +synonym: "juxtamembrane" BROAD [] +synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah] +synonym: "plasmalemma" EXACT [] +xref: NIF_Subcellular:sao1663586795 +xref: Wikipedia:Cell_membrane +is_a: GO:0016020 ! membrane +relationship: part_of GO:0071944 ! cell periphery + +[Term] +id: GO:0005887 +name: integral component of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] +synonym: "integral to plasma membrane" NARROW [] +is_a: GO:0016021 ! integral component of membrane +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0005888 +name: obsolete proteoglycan integral to plasma membrane +namespace: cellular_component +def: "OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators] +comment: This term was made obsolete because it describes the composition (i.e. proteoglycan) and not the location of a gene product. +synonym: "proteoglycan integral to plasma membrane" EXACT [] +is_obsolete: true +replaced_by: GO:0005887 + +[Term] +id: GO:0005889 +name: potassium:proton exchanging ATPase complex +namespace: cellular_component +def: "A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present." [PMID:11756431] +synonym: "hydrogen/potassium-exchanging ATPase complex" EXACT [] +synonym: "hydrogen:potassium-exchanging ATPase complex" EXACT [] +synonym: "proton pump" BROAD [] +is_a: GO:0090533 ! cation-transporting ATPase complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005890 +name: sodium:potassium-exchanging ATPase complex +namespace: cellular_component +def: "Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior." [ISBN:0198506732] +synonym: "sodium pump" BROAD [] +synonym: "sodium/potassium-exchanging ATPase complex" EXACT [] +is_a: GO:0090533 ! cation-transporting ATPase complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005891 +name: voltage-gated calcium channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential." [GOC:mah] +subset: goslim_pir +synonym: "voltage gated calcium channel complex" EXACT [] +synonym: "voltage-dependent calcium channel complex" EXACT [] +synonym: "voltage-sensitive calcium channel complex" EXACT [] +is_a: GO:0034704 ! calcium channel complex +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0005892 +name: acetylcholine-gated channel complex +namespace: cellular_component +def: "A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding." [GOC:bf, GOC:mah, PMID:12381728, PMID:15579462] +synonym: "nicotinic acetylcholine receptor" BROAD [] +synonym: "nicotinic acetylcholine-gated receptor-channel complex" EXACT [GOC:bf] +is_a: GO:0034702 ! ion channel complex +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005893 +name: interleukin-2 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits." [GOC:mah, PMID:3116143, PMID:8266078] +synonym: "IL-2 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005894 +name: interleukin-3 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5." [PMID:11839579] +synonym: "IL-3 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005895 +name: interleukin-5 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3." [GOC:mah, PMID:11312115, PMID:11839579] +synonym: "IL-5 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005896 +name: interleukin-6 receptor complex +namespace: cellular_component +def: "A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130." [PMID:8083235] +synonym: "IL-6 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005897 +name: interleukin-9 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins." [GOC:mah, PMID:10642536] +synonym: "IL-9 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005898 +name: interleukin-13 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain." [PMID:8552669, PMID:9013879] +synonym: "IL-13 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005899 +name: insulin receptor complex +namespace: cellular_component +def: "A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain." [ISBN:0198506732] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +is_a: GO:1902911 ! protein kinase complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005900 +name: oncostatin-M receptor complex +namespace: cellular_component +def: "A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta." [GOC:jl, PMID:8999038] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0005901 +name: caveola +namespace: cellular_component +alt_id: GO:0016599 +def: "A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm." [GOC:mah, ISBN:0721662544, PMID:16645198] +synonym: "caveolae" EXACT [] +synonym: "caveolar membrane" RELATED [] +xref: Wikipedia:Caveolae +is_a: GO:0044853 ! plasma membrane raft + +[Term] +id: GO:0005902 +name: microvillus +namespace: cellular_component +def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194] +comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta. +subset: goslim_pir +synonym: "microvilli" RELATED [NIF_Subcellular:sao671419673] +xref: NIF_Subcellular:sao671419673 +xref: Wikipedia:Microvillus +is_a: GO:0098858 ! actin-based cell projection +relationship: has_part GO:0032432 ! actin filament bundle + +[Term] +id: GO:0005903 +name: brush border +namespace: cellular_component +def: "The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell." [GOC:sl, ISBN:0815316194] +subset: goslim_pir +xref: Wikipedia:Brush_border +is_a: GO:0098862 ! cluster of actin-based cell projections +relationship: has_part GO:0005902 ! microvillus + +[Term] +id: GO:0005905 +name: clathrin-coated pit +namespace: cellular_component +def: "A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes." [GOC:mah, ISBN:0198506732, NIF_Subcellular:sao1969557946, PMID:10559856, PMID:17284835] +synonym: "coated pit" EXACT [GOC:bf] +xref: NIF_Subcellular:sao1969557946 +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0005906 +name: obsolete clathrin adaptor +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was positioned incorrectly, so the replacement term has a definition different from what this term appeared to mean. +synonym: "adaptin" RELATED [] +synonym: "clathrin adaptor" EXACT [] +is_obsolete: true +replaced_by: GO:0030119 + +[Term] +id: GO:0005907 +name: obsolete HA1 clathrin adaptor +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous. +synonym: "AP1" RELATED [] +synonym: "HA1 clathrin adaptor" EXACT [] +is_obsolete: true +consider: GO:0030121 + +[Term] +id: GO:0005908 +name: obsolete HA2 clathrin adaptor +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous. +synonym: "AP2" RELATED [] +synonym: "HA2 clathrin adaptor" EXACT [] +is_obsolete: true +consider: GO:0030122 + +[Term] +id: GO:0005911 +name: cell-cell junction +namespace: cellular_component +def: "A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] +synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368] +xref: NIF_Subcellular:sao1922892319 +is_a: GO:0070161 ! anchoring junction + +[Term] +id: GO:0005912 +name: adherens junction +namespace: cellular_component +alt_id: GO:0005913 +def: "A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules." [GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264] +synonym: "cell-cell adherens junction" EXACT [] +xref: Wikipedia:Adherens_junction +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0005914 +name: spot adherens junction +namespace: cellular_component +def: "A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens." [PMID:11700298] +synonym: "dense plaque" BROAD [] +synonym: "punctum adherens" EXACT [] +is_a: GO:0005912 ! adherens junction + +[Term] +id: GO:0005915 +name: zonula adherens +namespace: cellular_component +def: "A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells." [ISBN:0815316208] +synonym: "adhesion belt" EXACT [] +synonym: "belt desmosome" EXACT [] +synonym: "intermediate junction" EXACT [] +synonym: "zonula adhaerens" EXACT [] +xref: NIF_Subcellular:sao1400623473 +is_a: GO:0005912 ! adherens junction +relationship: part_of GO:0043296 ! apical junction complex + +[Term] +id: GO:0005916 +name: fascia adherens +namespace: cellular_component +def: "A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes." [GOC:aruk, GOC:bc, GOC:mtg_muscle, PMID:11732910] +xref: Wikipedia:Fascia_adherens +is_a: GO:0005911 ! cell-cell junction +relationship: part_of GO:0014704 ! intercalated disc + +[Term] +id: GO:0005917 +name: nephrocyte diaphragm +namespace: cellular_component +def: "A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates." [GOC:mtg_kidney_jan10, GOC:sart, PMID:18971929] +synonym: "nephrocyte junction" RELATED [PMID:8314002] +is_a: GO:0036056 ! filtration diaphragm + +[Term] +id: GO:0005918 +name: septate junction +namespace: cellular_component +def: "A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods." [ISBN:0815332181, PMID:11700298, PMID:12612641, PMID:20795303, PMID:28636800] +synonym: "septate desmosome" RELATED [] +xref: NIF_Subcellular:sao427941916 +is_a: GO:0070160 ! tight junction +relationship: part_of GO:0043296 ! apical junction complex + +[Term] +id: GO:0005919 +name: pleated septate junction +namespace: cellular_component +def: "A septate junction in which regular arrays of electron-dense septae span the intermembrane space." [PMID:11700298] +synonym: "pleated desmosome" RELATED [] +is_a: GO:0005918 ! septate junction + +[Term] +id: GO:0005920 +name: smooth septate junction +namespace: cellular_component +def: "A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions." [PMID:11700298] +synonym: "zonula continua" EXACT [] +is_a: GO:0005918 ! septate junction + +[Term] +id: GO:0005921 +name: gap junction +namespace: cellular_component +def: "A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181, PMID:22366062, Wikipedia:Gap_junction] +synonym: "communicating junction" EXACT [] +synonym: "electrical synapse" RELATED [Wikipedia:Gap_junction] +synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124] +synonym: "gap junction macula" EXACT [NIF_Subcellular:sao700839054] +synonym: "gap junction plaque" EXACT [NIF_Subcellular:sao700839054] +synonym: "intercellular gap junction channel" RELATED [] +synonym: "macula communicans" EXACT [] +synonym: "zonula communicans" EXACT [] +xref: NIF_Subcellular:sao118541872 +xref: Wikipedia:Gap_junction +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0005922 +name: connexin complex +namespace: cellular_component +def: "An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction." [PMID:11146276] +synonym: "connexon" EXACT [GOC:cjm] +synonym: "connexon complex" RELATED [] +xref: NIF_Subcellular:sao445019788 +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005921 ! gap junction + +[Term] +id: GO:0005923 +name: bicellular tight junction +namespace: cellular_component +def: "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." [GOC:mah, ISBN:0815332181] +synonym: "zonula occludens" EXACT [] +xref: NIF_Subcellular:sao1939999134 +xref: Wikipedia:Tight_junction +is_a: GO:0070160 ! tight junction +relationship: part_of GO:0043296 ! apical junction complex + +[Term] +id: GO:0005924 +name: obsolete cell-substrate adherens junction +namespace: cellular_component +def: "OBSOLETE. An adherens junction which connects a cell to the extracellular matrix." [GOC:hb] +comment: The reason for obsoletion is that, based on the most recent literature, there is no such structure in biology as 'cell-substrate adherens junction'. An 'adherens junction' is always a 'cell-cell junction' (PMIDs: 20571587, 17854762, 21422226, 28096264, 28401269, 26923917). +synonym: "hemi-adherens junction" RELATED [] +is_obsolete: true + +[Term] +id: GO:0005925 +name: focal adhesion +namespace: cellular_component +alt_id: GO:0005926 +alt_id: GO:0008357 +def: "A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ)." [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002] +synonym: "adhesion plaque" RELATED [PMID:3332661] +synonym: "connecting hemi-adherens junction" EXACT [] +synonym: "focal contact" EXACT [] +synonym: "HAJ" EXACT [] +synonym: "hemi-adherens junction" EXACT [] +xref: Wikipedia:Focal_adhesion +is_a: GO:0030055 ! cell-substrate junction + +[Term] +id: GO:0005927 +name: muscle tendon junction +namespace: cellular_component +def: "A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons." [GOC:mtg_muscle, PMID:12842007] +synonym: "myotendinous junction" EXACT [] +is_a: GO:0030055 ! cell-substrate junction + +[Term] +id: GO:0005928 +name: obsolete apical hemi-adherens junction +namespace: cellular_component +def: "OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle." [GOC:mah, PMID:11700298] +comment: The reason for obsoletion is that this term has not been used for GO annotation at all since 2001 when it was created, it has no children, it is not a part of any subset/slim. +synonym: "apical cell-substrate adherens junction" EXACT [GOC:mah] +synonym: "apical dense plaque" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005929 +name: cilium +namespace: cellular_component +alt_id: GO:0072372 +def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +synonym: "eukaryotic flagellum" EXACT [] +synonym: "flagellum" RELATED [] +synonym: "microtubule-based flagellum" EXACT [] +synonym: "primary cilium" NARROW [] +xref: FMA:67181 +xref: NIF_Subcellular:sao787716553 +xref: Wikipedia:Cilium +is_a: GO:0043226 ! organelle +is_a: GO:0120025 ! plasma membrane bounded cell projection +relationship: has_part GO:0030990 ! intraciliary transport particle +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +property_value: RO:0002161 NCBITaxon:4890 +property_value: RO:0002161 NCBITaxon:5782 + +[Term] +id: GO:0005930 +name: axoneme +namespace: cellular_component +alt_id: GO:0035085 +alt_id: GO:0035086 +def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane. +subset: goslim_pir +synonym: "ciliary axoneme" EXACT [] +synonym: "cilium axoneme" EXACT [] +synonym: "flagellar axoneme" EXACT [] +synonym: "flagellum axoneme" EXACT [] +xref: Wikipedia:Axoneme +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005874 ! microtubule +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0097014 ! ciliary plasm + +[Term] +id: GO:0005931 +name: axonemal nexin link +namespace: cellular_component +def: "A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules." [GOC:cilia, GOC:krc, ISBN:0198506732, PMID:21586547, PMID:21728999, PMID:22683354, PMID:9295136] +synonym: "axonemal interdoublet link" EXACT [] +synonym: "nexin complex" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005930 ! axoneme + +[Term] +id: GO:0005933 +name: cellular bud +namespace: cellular_component +def: "A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated." [GOC:sgd_curators] +subset: goslim_candida +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0110165 ! cellular anatomical entity +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0005934 +name: cellular bud tip +namespace: cellular_component +def: "The end of a cellular bud distal to the site of attachment to the mother cell." [GOC:mah] +is_a: GO:0030427 ! site of polarized growth +relationship: part_of GO:0005933 ! cellular bud + +[Term] +id: GO:0005935 +name: cellular bud neck +namespace: cellular_component +def: "The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding." [GOC:mah] +is_a: GO:0030427 ! site of polarized growth +relationship: part_of GO:0005933 ! cellular bud + +[Term] +id: GO:0005936 +name: obsolete shmoo +namespace: cellular_component +def: "OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles." [GOC:mah, GOC:mcc] +comment: This term was made obsolete because it represents a type of whole cell rather than a cellular component. To update annotations, consider the external ontology term 'shmoo ; FAO:0001023'. +synonym: "shmoo" EXACT [] +is_obsolete: true +consider: GO:0001400 +consider: GO:0005937 + +[Term] +id: GO:0005937 +name: mating projection +namespace: cellular_component +def: "The projection formed by unicellular fungi in response to mating pheromone." [GOC:mcc] +subset: goslim_pir +synonym: "conjugation tube" NARROW [] +synonym: "shmoo" NARROW [] +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0005938 +name: cell cortex +namespace: cellular_component +def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_yeast +synonym: "cell periphery" RELATED [] +synonym: "peripheral cytoplasm" RELATED [] +xref: Wikipedia:Cell_cortex +is_a: GO:0005737 ! cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0071944 ! cell periphery +relationship: part_of GO:0071944 ! cell periphery + +[Term] +id: GO:0005940 +name: septin ring +namespace: cellular_component +alt_id: GO:0030481 +def: "A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form." [GOC:krc, GOC:mah, PMID:16009555, PMID:16151244] +xref: Wikipedia:Septin_ring +is_a: GO:0032156 ! septin cytoskeleton +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0005941 +name: obsolete unlocalized protein complex +namespace: cellular_component +def: "OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products." [GOC:ma] +comment: This term was made obsolete because it was originally intended only as a temporary parent for protein complex terms for which no more specific parents had been found. This term no longer has any children: All protein complex terms are is_a 'protein complex ; GO:0043234' and nearly all have been placed under parents to yield more specific paths traversing a part_of relationship. In other words, the term has been superseded by other terms and relationships in the cellular component ontology, and is no longer needed. +synonym: "unlocalized protein complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005942 +name: phosphatidylinositol 3-kinase complex +namespace: cellular_component +def: "A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too." [GOC:bf, PMID:24587488] +comment: For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/ +subset: goslim_pir +synonym: "1-phosphatidylinositol 3-kinase complex" EXACT [] +synonym: "phosphoinositide 3-kinase complex" EXACT [] +synonym: "PI3-kinase p85-subunit alpha- PI3-kinase p110 complex" NARROW [CORUM:2575] +synonym: "PI3K complex" EXACT [] +synonym: "PIK3C3-PIK3R4 complex" NARROW [CORUM:429] +synonym: "PIK3CA-PIK3R1 complex" NARROW [CORUM:439] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0019898 ! extrinsic component of membrane + +[Term] +id: GO:0005943 +name: phosphatidylinositol 3-kinase complex, class IA +namespace: cellular_component +alt_id: GO:0035030 +def: "A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways." [PMID:9255069, PMID:9759495] +synonym: "1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex" EXACT [] +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA complex" EXACT [] +synonym: "class IA PI3K complex" EXACT [] +synonym: "phosphoinositide 3-kinase complex, class IA" EXACT [] +is_a: GO:0097651 ! phosphatidylinositol 3-kinase complex, class I + +[Term] +id: GO:0005944 +name: phosphatidylinositol 3-kinase complex, class IB +namespace: cellular_component +alt_id: GO:0035031 +def: "A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks." [PMID:9255069, PMID:9759495] +synonym: "1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex" EXACT [] +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IB complex" RELATED [] +synonym: "class IB PI3K complex" EXACT [] +synonym: "phosphoinositide 3-kinase complex, class IB" EXACT [] +is_a: GO:0097651 ! phosphatidylinositol 3-kinase complex, class I + +[Term] +id: GO:0005945 +name: 6-phosphofructokinase complex +namespace: cellular_component +def: "A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known." [GOC:mah, GOC:vw, ISBN:0198506732] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005946 +name: alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) +namespace: cellular_component +def: "A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present." [PMID:9837904] +comment: See also the molecular function term 'alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity ; GO:0003825'. +synonym: "trehalose-6-phosphate synthase complex" EXACT [] +synonym: "trehalose-6-phosphate synthase/phosphatase" EXACT [] +synonym: "UDP-glucose-glucosephosphate glucosyltransferase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005947 +name: mitochondrial alpha-ketoglutarate dehydrogenase complex +namespace: cellular_component +def: "Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah, GOC:mtg_sensu] +synonym: "2-oxoglutarate dehydrogenase complex" BROAD [] +is_a: GO:0030062 ! mitochondrial tricarboxylic acid cycle enzyme complex +is_a: GO:0045240 ! dihydrolipoyl dehydrogenase complex +intersection_of: GO:0045240 ! dihydrolipoyl dehydrogenase complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0005948 +name: acetolactate synthase complex +namespace: cellular_component +def: "A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate." [BRENDA:2.2.1.6, GOC:jl, PMID:16458324, PMID:8756689] +comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'. +synonym: "acetohydroxyacid synthase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005949 +name: obsolete aminoadipate-semialdehyde dehydrogenase complex +namespace: cellular_component +def: "OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde." [EC:1.2.1.31] +comment: This term was made obsolete because the catalytic activity resides in a single polypeptide that is not part of a complex with other gene products. +synonym: "aminoadipate-semialdehyde dehydrogenase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0005950 +name: anthranilate synthase complex +namespace: cellular_component +def: "A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine." [EC:4.1.3.27, MetaCyc:ANTHRANSYN-CPLX, PMID:4886290] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005951 +name: carbamoyl-phosphate synthase complex +namespace: cellular_component +def: "A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events." [PMID:8626695] +comment: Note that in higher eukaryotes, carbamoyl-phosphate synthase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term. +synonym: "arginine-specific carbamoyl phosphate synthetase complex" NARROW [] +synonym: "carbamoyl phosphate synthase complex" EXACT [] +synonym: "carbamoyl-phosphate synthase arginine-specific complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005952 +name: cAMP-dependent protein kinase complex +namespace: cellular_component +def: "An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer." [EC:2.7.11.11, ISBN:0198506732] +synonym: "3',5' cAMP-dependent protein kinase complex" EXACT [] +synonym: "3',5'-cAMP-dependent protein kinase complex" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase complex" EXACT [] +synonym: "cyclic AMP-dependent protein kinase complex" EXACT [] +synonym: "PKA" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005953 +name: CAAX-protein geranylgeranyltransferase complex +namespace: cellular_component +def: "A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane." [PMID:9781874] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005954 +name: calcium- and calmodulin-dependent protein kinase complex +namespace: cellular_component +def: "An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins." [EC:2.7.11.17] +synonym: "calcium/calmodulin-dependent protein kinase complex" EXACT [] +synonym: "CAMK2" EXACT [] +synonym: "CaMKII" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005955 +name: calcineurin complex +namespace: cellular_component +def: "A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin." [PMID:26794871] +synonym: "calcium-dependent protein serine/threonine phosphatase complex" NARROW [] +synonym: "protein phosphatase type 2B complex" EXACT [] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005956 +name: protein kinase CK2 complex +namespace: cellular_component +def: "A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein." [GOC:mah, PMID:10994779] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. +synonym: "casein kinase II complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005957 +name: obsolete debranching enzyme +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it is ambiguous (there are several debranching enzymes) and because it probably represents the glycogen debranching enzyme which is a single gene product and not a complex. +synonym: "debranching enzyme" EXACT [] +is_obsolete: true +consider: GO:0043033 + +[Term] +id: GO:0005958 +name: DNA-dependent protein kinase-DNA ligase 4 complex +namespace: cellular_component +alt_id: GO:0005959 +def: "A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV." [GOC:jl, GOC:mah, PMID:10854421, PMID:12235392, PMID:17072889] +is_a: GO:0070419 ! nonhomologous end joining complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0005960 +name: glycine cleavage complex +namespace: cellular_component +alt_id: GO:0005961 +alt_id: GO:0070015 +def: "A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T." [GOC:mah, MetaCyc:GCVMULTI-CPLX] +subset: goslim_pir +synonym: "glycine cleavage system" EXACT [] +synonym: "glycine decarboxylase complex" EXACT [] +synonym: "glycine dehydrogenase (decarboxylating) complex" EXACT [] +synonym: "glycine dehydrogenase complex (decarboxylating)" RELATED [] +synonym: "glycine synthase complex" EXACT [] +xref: Wikipedia:Glycine_decarboxylase_complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005962 +name: mitochondrial isocitrate dehydrogenase complex (NAD+) +namespace: cellular_component +def: "Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'isocitrate dehydrogenase (NAD+) activity ; GO:0004449'. +is_a: GO:0030062 ! mitochondrial tricarboxylic acid cycle enzyme complex +is_a: GO:0045242 ! isocitrate dehydrogenase complex (NAD+) +intersection_of: GO:0045242 ! isocitrate dehydrogenase complex (NAD+) +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0005963 +name: magnesium-dependent protein serine/threonine phosphatase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase." [EC:3.1.3.16] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0005964 +name: phosphorylase kinase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a." [EC:2.7.11.19] +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005965 +name: protein farnesyltransferase complex +namespace: cellular_component +def: "A protein complex that possesses protein farnesyltransferase activity." [GOC:mah] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005966 +name: cyclic-nucleotide phosphodiesterase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide." [EC:3.1.4.-] +synonym: "photoreceptor cyclic-nucleotide phosphodiesterase complex" NARROW [] +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0005967 +name: mitochondrial pyruvate dehydrogenase complex +namespace: cellular_component +def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase." [GOC:mtg_sensu, ISBN:0471331309, ISBN:0716720094] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. +synonym: "pyruvate dehydrogenase complex (lipoamide)" BROAD [] +is_a: GO:0045254 ! pyruvate dehydrogenase complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0045254 ! pyruvate dehydrogenase complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0005968 +name: Rab-protein geranylgeranyltransferase complex +namespace: cellular_component +def: "An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein)." [GOC:jl, PMID:11886217] +synonym: "GGTase-II complex" EXACT [] +synonym: "Rab geranylgeranyltransferase complex" EXACT [] +synonym: "RAB-protein geranylgeranyltransferase complex" EXACT [] +synonym: "RabGGTase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005969 +name: serine-pyruvate aminotransferase complex +namespace: cellular_component +alt_id: GO:0005970 +def: "An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate." [EC:2.6.1.51] +synonym: "serine-pyruvate aminotransferase, type 1 complex" NARROW [] +synonym: "serine-pyruvate aminotransferase, type 2B complex" NARROW [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0005971 +name: ribonucleoside-diphosphate reductase complex +namespace: cellular_component +def: "An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor." [BRENDA:1.17.4.1] +synonym: "ribonucleotide reductase complex" EXACT [GOC:mah] +synonym: "RNR complex" EXACT [GOC:mah] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0005972 +name: obsolete fibrinogen alpha chain +namespace: cellular_component +alt_id: GO:0008005 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "fibrinogen alpha chain" EXACT [] +is_obsolete: true +consider: GO:0005577 + +[Term] +id: GO:0005973 +name: obsolete fibrinogen beta chain +namespace: cellular_component +alt_id: GO:0008006 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "fibrinogen beta chain" EXACT [] +is_obsolete: true +consider: GO:0005577 + +[Term] +id: GO:0005974 +name: obsolete fibrinogen gamma chain +namespace: cellular_component +alt_id: GO:0008007 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "fibrinogen gamma chain" EXACT [] +is_obsolete: true +consider: GO:0005577 + +[Term] +id: GO:0005975 +name: carbohydrate metabolic process +namespace: biological_process +alt_id: GO:0044261 +alt_id: GO:0044723 +def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule." [GOC:mah, ISBN:0198506732] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_pombe +subset: goslim_yeast +synonym: "carbohydrate metabolism" EXACT [] +synonym: "multicellular organismal carbohydrate metabolic process" NARROW [] +synonym: "single-organism carbohydrate metabolic process" RELATED [] +xref: Wikipedia:Carbohydrate_metabolism +is_a: GO:0044238 ! primary metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: jl +creation_date: 2012-10-23T15:40:34Z + +[Term] +id: GO:0005976 +name: polysaccharide metabolic process +namespace: biological_process +alt_id: GO:0044263 +def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684] +subset: goslim_pir +synonym: "glycan metabolic process" NARROW [] +synonym: "glycan metabolism" NARROW [] +synonym: "multicellular organismal polysaccharide metabolic process" NARROW [] +synonym: "polysaccharide metabolism" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0005977 +name: glycogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] +synonym: "glycogen metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process +is_a: GO:0006112 ! energy reserve metabolic process + +[Term] +id: GO:0005978 +name: glycogen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] +synonym: "glycogen anabolism" EXACT [] +synonym: "glycogen biosynthesis" EXACT [] +synonym: "glycogen formation" EXACT [] +synonym: "glycogen synthesis" EXACT [] +xref: MetaCyc:GLYCOGENSYNTH-PWY +is_a: GO:0005977 ! glycogen metabolic process +is_a: GO:0009250 ! glucan biosynthetic process + +[Term] +id: GO:0005979 +name: regulation of glycogen biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] +synonym: "regulation of glycogen anabolism" EXACT [] +synonym: "regulation of glycogen biosynthesis" EXACT [] +synonym: "regulation of glycogen formation" EXACT [] +synonym: "regulation of glycogen synthesis" EXACT [] +is_a: GO:0010962 ! regulation of glucan biosynthetic process +is_a: GO:0070873 ! regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005978 ! glycogen biosynthetic process +relationship: regulates GO:0005978 ! glycogen biosynthetic process + +[Term] +id: GO:0005980 +name: glycogen catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] +synonym: "glycogen breakdown" EXACT [] +synonym: "glycogen catabolism" EXACT [] +synonym: "glycogen degradation" EXACT [] +synonym: "glycogenolysis" EXACT [GOC:sl] +xref: MetaCyc:GLYCOCAT-PWY +is_a: GO:0005977 ! glycogen metabolic process +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process + +[Term] +id: GO:0005981 +name: regulation of glycogen catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] +synonym: "regulation of glycogen breakdown" EXACT [] +synonym: "regulation of glycogen catabolism" EXACT [] +synonym: "regulation of glycogen degradation" EXACT [] +synonym: "regulation of glycogenolysis" EXACT [GOC:sl] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0070873 ! regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005980 ! glycogen catabolic process +relationship: regulates GO:0005980 ! glycogen catabolic process + +[Term] +id: GO:0005982 +name: starch metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose." [ISBN:0198506732] +synonym: "starch metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process + +[Term] +id: GO:0005983 +name: starch catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants." [GOC:ai] +synonym: "starch breakdown" EXACT [] +synonym: "starch catabolism" EXACT [] +synonym: "starch degradation" EXACT [] +xref: MetaCyc:PWY-842 +is_a: GO:0005982 ! starch metabolic process +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process + +[Term] +id: GO:0005984 +name: disaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units." [GOC:jl, ISBN:0192800981] +synonym: "disaccharide metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0005985 +name: sucrose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside." [GOC:go_curators] +synonym: "sucrose metabolism" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process + +[Term] +id: GO:0005986 +name: sucrose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside." [GOC:go_curators] +synonym: "sucrose anabolism" EXACT [] +synonym: "sucrose biosynthesis" EXACT [] +synonym: "sucrose formation" EXACT [] +synonym: "sucrose synthesis" EXACT [] +xref: MetaCyc:SUCSYN-PWY +is_a: GO:0005985 ! sucrose metabolic process +is_a: GO:0046351 ! disaccharide biosynthetic process + +[Term] +id: GO:0005987 +name: sucrose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside." [GOC:go_curators] +synonym: "sucrose breakdown" EXACT [] +synonym: "sucrose catabolism" EXACT [] +synonym: "sucrose degradation" EXACT [] +is_a: GO:0005985 ! sucrose metabolic process +is_a: GO:0046352 ! disaccharide catabolic process + +[Term] +id: GO:0005988 +name: lactose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose." [GOC:go_curators] +synonym: "lactose metabolism" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process + +[Term] +id: GO:0005989 +name: lactose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose." [GOC:go_curators] +synonym: "lactose anabolism" EXACT [] +synonym: "lactose biosynthesis" EXACT [] +synonym: "lactose formation" EXACT [] +synonym: "lactose synthesis" EXACT [] +is_a: GO:0005988 ! lactose metabolic process +is_a: GO:0046351 ! disaccharide biosynthetic process + +[Term] +id: GO:0005990 +name: lactose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose." [GOC:go_curators] +synonym: "lactose breakdown" EXACT [] +synonym: "lactose catabolism" EXACT [] +synonym: "lactose degradation" EXACT [] +is_a: GO:0005988 ! lactose metabolic process +is_a: GO:0046352 ! disaccharide catabolic process + +[Term] +id: GO:0005991 +name: trehalose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi." [GOC:jl, ISBN:0028623819] +synonym: "mycose metabolic process" EXACT [] +synonym: "mycose metabolism" EXACT [] +synonym: "mykose metabolic process" EXACT [] +synonym: "mykose metabolism" EXACT [] +synonym: "trehalose metabolism" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process + +[Term] +id: GO:0005992 +name: trehalose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi." [GOC:jl, ISBN:0028623819] +synonym: "mycose biosynthesis" EXACT [] +synonym: "mycose biosynthetic process" EXACT [] +synonym: "mykose biosynthesis" EXACT [] +synonym: "mykose biosynthetic process" EXACT [] +synonym: "trehalose anabolism" EXACT [] +synonym: "trehalose biosynthesis" EXACT [] +synonym: "trehalose formation" EXACT [] +synonym: "trehalose synthesis" EXACT [] +xref: MetaCyc:PWY-881 +xref: MetaCyc:TREHALOSESYN-PWY +xref: MetaCyc:TRESYN-PWY +is_a: GO:0005991 ! trehalose metabolic process +is_a: GO:0046351 ! disaccharide biosynthetic process + +[Term] +id: GO:0005993 +name: trehalose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi." [GOC:jl, ISBN:0028623819] +synonym: "mycose catabolic process" EXACT [] +synonym: "mycose catabolism" EXACT [] +synonym: "mykose catabolic process" EXACT [] +synonym: "mykose catabolism" EXACT [] +synonym: "trehalose breakdown" EXACT [] +synonym: "trehalose catabolism" EXACT [] +synonym: "trehalose degradation" EXACT [] +xref: MetaCyc:TREDEGLOW-PWY +is_a: GO:0005991 ! trehalose metabolic process +is_a: GO:0046352 ! disaccharide catabolic process + +[Term] +id: GO:0005994 +name: melibiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose." [ISBN:0198547684] +synonym: "melibiose metabolism" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process + +[Term] +id: GO:0005995 +name: melibiose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose." [ISBN:0198547684] +synonym: "melibiose breakdown" EXACT [] +synonym: "melibiose catabolism" EXACT [] +synonym: "melibiose degradation" EXACT [] +is_a: GO:0005994 ! melibiose metabolic process +is_a: GO:0046352 ! disaccharide catabolic process + +[Term] +id: GO:0005996 +name: monosaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] +synonym: "monosaccharide metabolism" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0005997 +name: xylulose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose." [ISBN:0198547684] +synonym: "xylulose metabolism" EXACT [] +is_a: GO:0019321 ! pentose metabolic process + +[Term] +id: GO:0005998 +name: xylulose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose." [ISBN:0198547684] +synonym: "xylulose breakdown" EXACT [] +synonym: "xylulose catabolism" EXACT [] +synonym: "xylulose degradation" EXACT [] +xref: MetaCyc:XYLCAT-PWY +is_a: GO:0005997 ! xylulose metabolic process +is_a: GO:0019323 ! pentose catabolic process + +[Term] +id: GO:0005999 +name: xylulose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose." [ISBN:0198547684] +synonym: "xylulose anabolism" EXACT [] +synonym: "xylulose biosynthesis" EXACT [] +synonym: "xylulose formation" EXACT [] +synonym: "xylulose synthesis" EXACT [] +is_a: GO:0005997 ! xylulose metabolic process +is_a: GO:0019322 ! pentose biosynthetic process + +[Term] +id: GO:0006000 +name: fructose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey." [ISBN:0198506732] +synonym: "fructose metabolism" EXACT [] +xref: Wikipedia:Fructose +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0006001 +name: fructose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose." [GOC:ai] +synonym: "fructose breakdown" EXACT [] +synonym: "fructose catabolism" EXACT [] +synonym: "fructose degradation" EXACT [] +is_a: GO:0006000 ! fructose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0006002 +name: fructose 6-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism." [ISBN:0198506732] +synonym: "fructose 6-phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0006003 +name: fructose 2,6-bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase." [ISBN:0198506732] +synonym: "fructose 2,6-bisphosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0006004 +name: fucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose." [ISBN:0198506732] +synonym: "fucose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0006005 +name: L-fucose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose)." [GOC:jl] +synonym: "L-fucose anabolism" EXACT [] +synonym: "L-fucose biosynthesis" EXACT [] +synonym: "L-fucose formation" EXACT [] +synonym: "L-fucose synthesis" EXACT [] +is_a: GO:0042353 ! fucose biosynthetic process +is_a: GO:0042354 ! L-fucose metabolic process + +[Term] +id: GO:0006006 +name: glucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732] +synonym: "cellular glucose metabolic process" EXACT [GOC:vw] +synonym: "glucose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0006007 +name: glucose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai] +synonym: "glucose breakdown" EXACT [] +synonym: "glucose catabolism" EXACT [] +synonym: "glucose degradation" EXACT [] +is_a: GO:0006006 ! glucose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0006009 +name: glucose 1-phosphate phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate." [GOC:ai] +is_a: GO:0016310 ! phosphorylation +is_a: GO:0019255 ! glucose 1-phosphate metabolic process + +[Term] +id: GO:0006011 +name: UDP-glucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-glucose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0006012 +name: galactose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [ISBN:0198506732] +synonym: "galactose metabolism" EXACT [] +xref: Wikipedia:Galactose +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0006013 +name: mannose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins." [ISBN:0198506732] +synonym: "mannose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0006014 +name: D-ribose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12." [ISBN:0198506732] +synonym: "D-ribose metabolism" EXACT [] +is_a: GO:0019321 ! pentose metabolic process + +[Term] +id: GO:0006015 +name: 5-phosphoribose 1-diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate." [GOC:ai] +synonym: "5-phosphoribose 1-diphosphate anabolism" EXACT [] +synonym: "5-phosphoribose 1-diphosphate biosynthesis" EXACT [] +synonym: "5-phosphoribose 1-diphosphate formation" EXACT [] +synonym: "5-phosphoribose 1-diphosphate synthesis" EXACT [] +synonym: "5-phosphoribosyl-1-pyrophosphate biosynthesis" EXACT [] +synonym: "5-phosphoribosyl-1-pyrophosphate biosynthetic process" EXACT [] +synonym: "PRPP biosynthetic process" EXACT [] +xref: MetaCyc:PWY0-661 +is_a: GO:0046390 ! ribose phosphate biosynthetic process +is_a: GO:0046391 ! 5-phosphoribose 1-diphosphate metabolic process + +[Term] +id: GO:0006016 +name: 2-deoxyribose 1-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose." [ISBN:0198506732] +synonym: "2-deoxyribose 1-phosphate anabolism" EXACT [] +synonym: "2-deoxyribose 1-phosphate biosynthesis" EXACT [] +synonym: "2-deoxyribose 1-phosphate formation" EXACT [] +synonym: "2-deoxyribose 1-phosphate synthesis" EXACT [] +is_a: GO:0046384 ! 2-deoxyribose 1-phosphate metabolic process +is_a: GO:0046385 ! deoxyribose phosphate biosynthetic process + +[Term] +id: GO:0006017 +name: deoxyribose 1,5-bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose." [GOC:ai] +synonym: "deoxyribose 1,5-bisphosphate anabolism" EXACT [] +synonym: "deoxyribose 1,5-bisphosphate biosynthesis" EXACT [] +synonym: "deoxyribose 1,5-bisphosphate formation" EXACT [] +synonym: "deoxyribose 1,5-bisphosphate synthesis" EXACT [] +is_a: GO:0046385 ! deoxyribose phosphate biosynthetic process +is_a: GO:0046387 ! deoxyribose 1,5-bisphosphate metabolic process + +[Term] +id: GO:0006018 +name: 2-deoxyribose 1-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose." [GOC:ai] +synonym: "2-deoxyribose 1-phosphate breakdown" EXACT [] +synonym: "2-deoxyribose 1-phosphate catabolism" EXACT [] +synonym: "2-deoxyribose 1-phosphate degradation" EXACT [] +synonym: "deoxyribose 1-phosphate catabolic process" EXACT [GOC:mah] +is_a: GO:0046384 ! 2-deoxyribose 1-phosphate metabolic process +is_a: GO:0046386 ! deoxyribose phosphate catabolic process + +[Term] +id: GO:0006019 +name: deoxyribose 5-phosphate phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate." [GOC:ai] +is_a: GO:0016310 ! phosphorylation +is_a: GO:0046389 ! deoxyribose 5-phosphate metabolic process + +[Term] +id: GO:0006020 +name: inositol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms." [ISBN:0198547684] +synonym: "inositol metabolism" EXACT [] +synonym: "myo-inositol metabolic process" NARROW [] +synonym: "myo-inositol metabolism" NARROW [] +synonym: "vitamin Bh metabolic process" EXACT [] +synonym: "vitamin Bh metabolism" EXACT [] +xref: Wikipedia:Inositol +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0006021 +name: inositol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms." [ISBN:0198547684] +synonym: "inositol anabolism" EXACT [] +synonym: "inositol biosynthesis" EXACT [] +synonym: "inositol formation" EXACT [] +synonym: "inositol synthesis" EXACT [] +synonym: "myo-inositol biosynthesis" NARROW [] +synonym: "myo-inositol biosynthetic process" NARROW [] +synonym: "vitamin Bh biosynthesis" EXACT [] +synonym: "vitamin Bh biosynthetic process" EXACT [] +is_a: GO:0006020 ! inositol metabolic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process + +[Term] +id: GO:0006022 +name: aminoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] +synonym: "aminoglycan metabolism" EXACT [] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006023 +name: aminoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] +synonym: "aminoglycan anabolism" EXACT [] +synonym: "aminoglycan biosynthesis" EXACT [] +synonym: "aminoglycan formation" EXACT [] +synonym: "aminoglycan synthesis" EXACT [] +is_a: GO:0006022 ! aminoglycan metabolic process +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0006024 +name: glycosaminoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] +synonym: "glycosaminoglycan anabolism" EXACT [] +synonym: "glycosaminoglycan biosynthesis" EXACT [] +synonym: "glycosaminoglycan formation" EXACT [] +synonym: "glycosaminoglycan synthesis" EXACT [] +is_a: GO:0006023 ! aminoglycan biosynthetic process +is_a: GO:0030203 ! glycosaminoglycan metabolic process + +[Term] +id: GO:0006025 +name: galactosaminoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose." [GOC:ai] +synonym: "galactosaminoglycan anabolism" EXACT [] +synonym: "galactosaminoglycan biosynthesis" EXACT [] +synonym: "galactosaminoglycan formation" EXACT [] +synonym: "galactosaminoglycan synthesis" EXACT [] +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0046350 ! galactosaminoglycan metabolic process + +[Term] +id: GO:0006026 +name: aminoglycan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] +synonym: "aminoglycan breakdown" EXACT [] +synonym: "aminoglycan catabolism" EXACT [] +synonym: "aminoglycan degradation" EXACT [] +is_a: GO:0006022 ! aminoglycan metabolic process +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0006027 +name: glycosaminoglycan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] +synonym: "glycosaminoglycan breakdown" EXACT [] +synonym: "glycosaminoglycan catabolism" EXACT [] +synonym: "glycosaminoglycan degradation" EXACT [] +is_a: GO:0006026 ! aminoglycan catabolic process +is_a: GO:0030203 ! glycosaminoglycan metabolic process + +[Term] +id: GO:0006028 +name: galactosaminoglycan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose." [GOC:ai] +synonym: "galactosaminoglycan breakdown" EXACT [] +synonym: "galactosaminoglycan catabolism" EXACT [] +synonym: "galactosaminoglycan degradation" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0046350 ! galactosaminoglycan metabolic process + +[Term] +id: GO:0006029 +name: proteoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GOC:mah, ISBN:0198506732] +synonym: "proteoglycan metabolism" EXACT [] +synonym: "proteoglycan sulfate transfer" NARROW [] +is_a: GO:0009100 ! glycoprotein metabolic process + +[Term] +id: GO:0006030 +name: chitin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] +synonym: "beta-1,4-linked N-acetylglucosamine metabolic process" EXACT [] +synonym: "beta-1,4-linked N-acetylglucosamine metabolism" EXACT [] +synonym: "chitin metabolism" EXACT [] +is_a: GO:0006022 ! aminoglycan metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901071 ! glucosamine-containing compound metabolic process + +[Term] +id: GO:0006031 +name: chitin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] +synonym: "beta-1,4-linked N-acetylglucosamine biosynthesis" EXACT [] +synonym: "beta-1,4-linked N-acetylglucosamine biosynthetic process" EXACT [] +synonym: "chitin anabolism" EXACT [] +synonym: "chitin biosynthesis" EXACT [] +synonym: "chitin formation" EXACT [] +synonym: "chitin synthesis" EXACT [] +is_a: GO:0006023 ! aminoglycan biosynthetic process +is_a: GO:0006030 ! chitin metabolic process +is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process + +[Term] +id: GO:0006032 +name: chitin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] +synonym: "beta-1,4-linked N-acetylglucosamine catabolic process" EXACT [] +synonym: "beta-1,4-linked N-acetylglucosamine catabolism" EXACT [] +synonym: "chitin breakdown" EXACT [] +synonym: "chitin catabolism" EXACT [] +synonym: "chitin degradation" EXACT [] +is_a: GO:0006026 ! aminoglycan catabolic process +is_a: GO:0006030 ! chitin metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901072 ! glucosamine-containing compound catabolic process + +[Term] +id: GO:0006033 +name: chitin localization +namespace: biological_process +def: "A process in which chitin is transported to, or maintained in, a specific location." [GOC:ai] +synonym: "chitin localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of chitin localization" EXACT [] +is_a: GO:0033037 ! polysaccharide localization + +[Term] +id: GO:0006034 +name: cuticle chitin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles." [GOC:ai] +synonym: "cuticle chitin metabolism" EXACT [] +is_a: GO:0006030 ! chitin metabolic process + +[Term] +id: GO:0006035 +name: cuticle chitin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles." [GOC:ai] +synonym: "cuticle chitin anabolism" EXACT [] +synonym: "cuticle chitin biosynthesis" EXACT [] +synonym: "cuticle chitin formation" EXACT [] +synonym: "cuticle chitin synthesis" EXACT [] +is_a: GO:0006031 ! chitin biosynthetic process +is_a: GO:0006034 ! cuticle chitin metabolic process +relationship: part_of GO:0040003 ! chitin-based cuticle development + +[Term] +id: GO:0006036 +name: cuticle chitin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles." [GOC:ai] +synonym: "cuticle chitin breakdown" EXACT [] +synonym: "cuticle chitin catabolism" EXACT [] +synonym: "cuticle chitin degradation" EXACT [] +is_a: GO:0006032 ! chitin catabolic process +is_a: GO:0006034 ! cuticle chitin metabolic process + +[Term] +id: GO:0006037 +name: cell wall chitin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells." [GOC:ai] +synonym: "cell wall chitin metabolism" EXACT [] +is_a: GO:0006030 ! chitin metabolic process +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0006038 +name: cell wall chitin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells." [GOC:ai] +synonym: "cell wall chitin anabolism" EXACT [] +synonym: "cell wall chitin biosynthesis" EXACT [] +synonym: "cell wall chitin formation" EXACT [] +synonym: "cell wall chitin synthesis" EXACT [] +is_a: GO:0006031 ! chitin biosynthetic process +is_a: GO:0006037 ! cell wall chitin metabolic process +relationship: part_of GO:0042546 ! cell wall biogenesis + +[Term] +id: GO:0006039 +name: cell wall chitin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells." [GOC:ai] +synonym: "cell wall chitin breakdown" EXACT [] +synonym: "cell wall chitin catabolism" EXACT [] +synonym: "cell wall chitin degradation" EXACT [] +is_a: GO:0006032 ! chitin catabolic process +is_a: GO:0006037 ! cell wall chitin metabolic process + +[Term] +id: GO:0006040 +name: amino sugar metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] +synonym: "amino sugar metabolism" EXACT [] +synonym: "aminosaccharide metabolic process" EXACT [] +synonym: "aminosaccharide metabolism" EXACT [] +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0006041 +name: glucosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin." [GOC:jl, ISBN:0198506732] +synonym: "chitosamine metabolic process" EXACT [] +synonym: "chitosamine metabolism" EXACT [] +synonym: "glucosamine metabolism" EXACT [] +is_a: GO:1901071 ! glucosamine-containing compound metabolic process + +[Term] +id: GO:0006042 +name: glucosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin." [GOC:jl, ISBN:0198506732] +synonym: "chitosamine biosynthesis" EXACT [] +synonym: "chitosamine biosynthetic process" EXACT [] +synonym: "glucosamine anabolism" EXACT [] +synonym: "glucosamine biosynthesis" EXACT [] +synonym: "glucosamine formation" EXACT [] +synonym: "glucosamine synthesis" EXACT [] +is_a: GO:0006041 ! glucosamine metabolic process +is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process + +[Term] +id: GO:0006043 +name: glucosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin." [GOC:jl, ISBN:0198506732] +synonym: "chitosamine catabolic process" EXACT [] +synonym: "chitosamine catabolism" EXACT [] +synonym: "glucosamine breakdown" EXACT [] +synonym: "glucosamine catabolism" EXACT [] +synonym: "glucosamine degradation" EXACT [] +xref: MetaCyc:GLUAMCAT-PWY +is_a: GO:0006041 ! glucosamine metabolic process +is_a: GO:1901072 ! glucosamine-containing compound catabolic process + +[Term] +id: GO:0006044 +name: N-acetylglucosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [ISBN:0198506732] +synonym: "N-acetylglucosamine metabolism" EXACT [] +is_a: GO:1901071 ! glucosamine-containing compound metabolic process + +[Term] +id: GO:0006045 +name: N-acetylglucosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [ISBN:0198506732] +synonym: "N-acetylglucosamine anabolism" EXACT [] +synonym: "N-acetylglucosamine biosynthesis" EXACT [] +synonym: "N-acetylglucosamine formation" EXACT [] +synonym: "N-acetylglucosamine synthesis" EXACT [] +is_a: GO:0006044 ! N-acetylglucosamine metabolic process +is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process + +[Term] +id: GO:0006046 +name: N-acetylglucosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [ISBN:0198506732] +synonym: "N-acetylglucosamine breakdown" EXACT [] +synonym: "N-acetylglucosamine catabolism" EXACT [] +synonym: "N-acetylglucosamine degradation" EXACT [] +is_a: GO:0006044 ! N-acetylglucosamine metabolic process +is_a: GO:1901072 ! glucosamine-containing compound catabolic process + +[Term] +id: GO:0006047 +name: UDP-N-acetylglucosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylglucosamine metabolism" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0006048 +name: UDP-N-acetylglucosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-GlcNAc biosynthesis" EXACT [] +synonym: "UDP-GlcNAc biosynthetic process" EXACT [] +synonym: "UDP-N-acetylglucosamine anabolism" EXACT [] +synonym: "UDP-N-acetylglucosamine biosynthesis" EXACT [] +synonym: "UDP-N-acetylglucosamine formation" EXACT [] +synonym: "UDP-N-acetylglucosamine synthesis" EXACT [] +xref: MetaCyc:UDPNAGSYN-PWY +is_a: GO:0006047 ! UDP-N-acetylglucosamine metabolic process +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046349 ! amino sugar biosynthetic process + +[Term] +id: GO:0006049 +name: UDP-N-acetylglucosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylglucosamine breakdown" EXACT [] +synonym: "UDP-N-acetylglucosamine catabolism" EXACT [] +synonym: "UDP-N-acetylglucosamine degradation" EXACT [] +is_a: GO:0006047 ! UDP-N-acetylglucosamine metabolic process +is_a: GO:0009227 ! nucleotide-sugar catabolic process +is_a: GO:0046348 ! amino sugar catabolic process + +[Term] +id: GO:0006050 +name: mannosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins." [GOC:curators] +synonym: "mannosamine metabolism" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process + +[Term] +id: GO:0006051 +name: N-acetylmannosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose." [GOC:ai, ISBN:0198506732] +synonym: "N-acetylmannosamine metabolism" EXACT [] +is_a: GO:0006050 ! mannosamine metabolic process + +[Term] +id: GO:0006052 +name: N-acetylmannosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose." [GOC:ai, ISBN:0198506732] +synonym: "N-acetylmannosamine anabolism" EXACT [] +synonym: "N-acetylmannosamine biosynthesis" EXACT [] +synonym: "N-acetylmannosamine formation" EXACT [] +synonym: "N-acetylmannosamine synthesis" EXACT [] +is_a: GO:0006051 ! N-acetylmannosamine metabolic process +is_a: GO:0046347 ! mannosamine biosynthetic process + +[Term] +id: GO:0006053 +name: N-acetylmannosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose." [GOC:ai, ISBN:0198506732] +synonym: "N-acetylmannosamine breakdown" EXACT [] +synonym: "N-acetylmannosamine catabolism" EXACT [] +synonym: "N-acetylmannosamine degradation" EXACT [] +is_a: GO:0006051 ! N-acetylmannosamine metabolic process +is_a: GO:0046346 ! mannosamine catabolic process + +[Term] +id: GO:0006054 +name: N-acetylneuraminate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid." [ISBN:0198506732] +synonym: "N-acetylneuraminate metabolism" EXACT [] +synonym: "sialic acid metabolic process" BROAD [] +synonym: "sialic acid metabolism" BROAD [] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0006055 +name: CMP-N-acetylneuraminate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate." [GOC:ai] +synonym: "CMP-N-acetylneuraminate anabolism" EXACT [] +synonym: "CMP-N-acetylneuraminate biosynthesis" EXACT [] +synonym: "CMP-N-acetylneuraminate formation" EXACT [] +synonym: "CMP-N-acetylneuraminate synthesis" EXACT [] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046381 ! CMP-N-acetylneuraminate metabolic process + +[Term] +id: GO:0006056 +name: mannoprotein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannoproteins, any protein that contains covalently bound mannose residues." [ISBN:0198506732] +synonym: "mannoprotein metabolism" EXACT [] +is_a: GO:0009100 ! glycoprotein metabolic process + +[Term] +id: GO:0006057 +name: mannoprotein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannoproteins, any protein that contains covalently bound mannose residues." [ISBN:0198506732] +synonym: "mannoprotein anabolism" EXACT [] +synonym: "mannoprotein biosynthesis" EXACT [] +synonym: "mannoprotein formation" EXACT [] +synonym: "mannoprotein synthesis" EXACT [] +is_a: GO:0006056 ! mannoprotein metabolic process +is_a: GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0006058 +name: mannoprotein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannoproteins, any protein that contains covalently bound mannose residues." [ISBN:0198506732] +synonym: "mannoprotein breakdown" EXACT [] +synonym: "mannoprotein catabolism" EXACT [] +synonym: "mannoprotein degradation" EXACT [] +is_a: GO:0006056 ! mannoprotein metabolic process +is_a: GO:0006516 ! glycoprotein catabolic process +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process + +[Term] +id: GO:0006059 +name: hexitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexitol metabolism" EXACT [] +synonym: "sugar alcohol (hexitol) metabolic process" EXACT [] +synonym: "sugar alcohol (hexitol) metabolism" EXACT [] +is_a: GO:0019400 ! alditol metabolic process + +[Term] +id: GO:0006060 +name: sorbitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "sorbitol metabolism" EXACT [] +xref: MetaCyc:P461-PWY +is_a: GO:0006059 ! hexitol metabolic process + +[Term] +id: GO:0006061 +name: sorbitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "sorbitol anabolism" EXACT [] +synonym: "sorbitol biosynthesis" EXACT [] +synonym: "sorbitol formation" EXACT [] +synonym: "sorbitol synthesis" EXACT [] +is_a: GO:0006060 ! sorbitol metabolic process +is_a: GO:0019406 ! hexitol biosynthetic process + +[Term] +id: GO:0006062 +name: sorbitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "sorbitol breakdown" EXACT [] +synonym: "sorbitol catabolism" EXACT [] +synonym: "sorbitol degradation" EXACT [] +xref: MetaCyc:SORBDEG-PWY +is_a: GO:0006060 ! sorbitol metabolic process +is_a: GO:0019407 ! hexitol catabolic process + +[Term] +id: GO:0006063 +name: uronic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose." [ISBN:0198506732] +synonym: "uronic acid metabolism" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0006064 +name: glucuronate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid." [GOC:go_curators] +synonym: "glucuronate breakdown" EXACT [] +synonym: "glucuronate catabolism" EXACT [] +synonym: "glucuronate degradation" EXACT [] +is_a: GO:0019585 ! glucuronate metabolic process +is_a: GO:0046365 ! monosaccharide catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0006065 +name: UDP-glucuronate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-glucuronate anabolism" EXACT [] +synonym: "UDP-glucuronate biosynthesis" EXACT [] +synonym: "UDP-glucuronate formation" EXACT [] +synonym: "UDP-glucuronate synthesis" EXACT [] +xref: MetaCyc:PWY-4841 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0046398 ! UDP-glucuronate metabolic process + +[Term] +id: GO:0006066 +name: alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pir +synonym: "alcohol metabolism" EXACT [] +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0006067 +name: ethanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation." [GOC:ai, ISBN:0198506732] +synonym: "ethanol metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process + +[Term] +id: GO:0006068 +name: ethanol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation." [GOC:ai, ISBN:0198506732] +synonym: "ethanol breakdown" EXACT [] +synonym: "ethanol catabolism" EXACT [] +synonym: "ethanol degradation" EXACT [] +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0006069 +name: ethanol oxidation +namespace: biological_process +def: "An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate." [GOC:mah, MetaCyc:PWY66-161, MetaCyc:PWY66-162, MetaCyc:PWY66-21] +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006070 +name: octanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH." [GOC:go_curators] +synonym: "octanol metabolism" EXACT [] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:1903173 ! fatty alcohol metabolic process + +[Term] +id: GO:0006071 +name: glycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:ai, ISBN:0198506732] +synonym: "glycerol metabolism" EXACT [] +xref: MetaCyc:GLYCEROLMETAB-PWY +is_a: GO:0019400 ! alditol metabolic process + +[Term] +id: GO:0006072 +name: glycerol-3-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol." [GOC:go_curators, ISBN:0198506732] +synonym: "glycerol-3-phosphate metabolism" EXACT [] +is_a: GO:0052646 ! alditol phosphate metabolic process + +[Term] +id: GO:0006073 +name: cellular glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell." [ISBN:0198547684] +synonym: "cellular glucan metabolism" EXACT [] +is_a: GO:0044042 ! glucan metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0006074 +name: (1->3)-beta-D-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds." [ISBN:0198506732] +synonym: "1,3-beta-D-glucan metabolic process" BROAD [GOC:tb] +synonym: "1,3-beta-D-glucan metabolism" EXACT [] +synonym: "1,3-beta-glucan metabolic process" BROAD [GOC:tb] +synonym: "beta-1,3 glucan metabolic process" EXACT [] +synonym: "beta-1,3 glucan metabolism" EXACT [] +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0006075 +name: (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds." [GOC:ai] +synonym: "1,3-beta-D-glucan biosynthetic process" EXACT [] +synonym: "1,3-beta-glucan anabolism" EXACT [] +synonym: "1,3-beta-glucan biosynthesis" EXACT [] +synonym: "1,3-beta-glucan formation" EXACT [] +synonym: "1,3-beta-glucan synthesis" EXACT [] +synonym: "beta-1,3 glucan anabolism" EXACT [] +synonym: "beta-1,3 glucan biosynthesis" EXACT [] +synonym: "beta-1,3 glucan biosynthetic process" EXACT [] +synonym: "beta-1,3 glucan formation" EXACT [] +synonym: "beta-1,3 glucan synthesis" EXACT [] +is_a: GO:0006074 ! (1->3)-beta-D-glucan metabolic process +is_a: GO:0051274 ! beta-glucan biosynthetic process + +[Term] +id: GO:0006076 +name: (1->3)-beta-D-glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans." [GOC:ai] +synonym: "1,3-beta-D-glucan catabolic process" EXACT [] +synonym: "1,3-beta-glucan breakdown" EXACT [] +synonym: "1,3-beta-glucan catabolism" EXACT [] +synonym: "1,3-beta-glucan degradation" EXACT [] +synonym: "beta-1,3 glucan breakdown" EXACT [] +synonym: "beta-1,3 glucan catabolic process" EXACT [] +synonym: "beta-1,3 glucan catabolism" EXACT [] +synonym: "beta-1,3 glucan degradation" EXACT [] +is_a: GO:0006074 ! (1->3)-beta-D-glucan metabolic process +is_a: GO:0051275 ! beta-glucan catabolic process + +[Term] +id: GO:0006077 +name: (1->6)-beta-D-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds." [ISBN:0198506732] +synonym: "1,6-beta-glucan metabolic process" EXACT [] +synonym: "1,6-beta-glucan metabolism" EXACT [] +synonym: "beta-1,6 glucan metabolic process" EXACT [] +synonym: "beta-1,6 glucan metabolism" EXACT [] +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0006078 +name: (1->6)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans." [GOC:ai] +synonym: "1,6-beta-glucan anabolism" EXACT [] +synonym: "1,6-beta-glucan biosynthesis" EXACT [] +synonym: "1,6-beta-glucan biosynthetic process" EXACT [] +synonym: "1,6-beta-glucan formation" EXACT [] +synonym: "1,6-beta-glucan synthesis" EXACT [] +synonym: "beta-1,6 glucan anabolism" EXACT [] +synonym: "beta-1,6 glucan biosynthesis" EXACT [] +synonym: "beta-1,6 glucan biosynthetic process" EXACT [] +synonym: "beta-1,6 glucan formation" EXACT [] +synonym: "beta-1,6 glucan synthesis" EXACT [] +is_a: GO:0006077 ! (1->6)-beta-D-glucan metabolic process +is_a: GO:0051274 ! beta-glucan biosynthetic process + +[Term] +id: GO:0006079 +name: (1->6)-beta-D-glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans." [GOC:ai] +synonym: "1,6-beta-D-glucan breakdown" EXACT [] +synonym: "1,6-beta-D-glucan catabolic process" EXACT [] +synonym: "1,6-beta-D-glucan catabolism" EXACT [] +synonym: "1,6-beta-D-glucan degradation" EXACT [] +synonym: "beta-1,6 glucan breakdown" EXACT [] +synonym: "beta-1,6 glucan catabolic process" EXACT [] +synonym: "beta-1,6 glucan catabolism" EXACT [] +synonym: "beta-1,6 glucan degradation" EXACT [] +is_a: GO:0006077 ! (1->6)-beta-D-glucan metabolic process +is_a: GO:0051275 ! beta-glucan catabolic process + +[Term] +id: GO:0006080 +name: substituted mannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units." [GOC:tair_curators] +synonym: "substituted mannan metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0006081 +name: cellular aldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells." [GOC:go_curators, ISBN:0198506732] +subset: goslim_pir +synonym: "aldehyde metabolism" EXACT [] +synonym: "alkanal metabolic process" EXACT [] +synonym: "alkanal metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0006082 +name: organic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] +subset: goslim_pir +synonym: "organic acid metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0006083 +name: acetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] +synonym: "acetate metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0006084 +name: acetyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [ISBN:0198547684] +synonym: "acetyl coenzyme A metabolic process" EXACT [] +synonym: "acetyl coenzyme A metabolism" EXACT [] +synonym: "acetyl-CoA metabolism" EXACT [] +is_a: GO:0006637 ! acyl-CoA metabolic process + +[Term] +id: GO:0006085 +name: acetyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated." [GOC:go_curators] +synonym: "acetyl-CoA anabolism" EXACT [] +synonym: "acetyl-CoA biosynthesis" EXACT [] +synonym: "acetyl-CoA formation" EXACT [] +synonym: "acetyl-CoA synthesis" EXACT [] +xref: MetaCyc:PWY-5173 +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0071616 ! acyl-CoA biosynthetic process + +[Term] +id: GO:0006086 +name: acetyl-CoA biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "acetyl-CoA anabolism from pyruvate" EXACT [] +synonym: "acetyl-CoA formation from pyruvate" EXACT [] +synonym: "acetyl-CoA synthesis from pyruvate" EXACT [] +synonym: "pyruvate dehydrogenase pathway" EXACT [] +xref: MetaCyc:PYRUVDEHYD-PWY +is_a: GO:0006085 ! acetyl-CoA biosynthetic process +is_a: GO:0006090 ! pyruvate metabolic process + +[Term] +id: GO:0006088 +name: obsolete acetate to acetyl-CoA +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "acetate to acetyl-CoA" EXACT [] +is_obsolete: true +consider: GO:0003987 + +[Term] +id: GO:0006089 +name: lactate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lactate, the anion of lactic acid." [ISBN:0198547684] +synonym: "2-hydroxypropanoate metabolic process" EXACT [] +synonym: "2-hydroxypropanoate metabolism" EXACT [] +synonym: "alpha-hydroxypropionate metabolic process" EXACT [] +synonym: "alpha-hydroxypropionate metabolism" EXACT [] +synonym: "lactate metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0006090 +name: pyruvate metabolic process +namespace: biological_process +alt_id: GO:0006087 +def: "The chemical reactions and pathways involving pyruvate, 2-oxopropanoate." [GOC:go_curators] +synonym: "pyruvate dehydrogenase bypass" RELATED [] +synonym: "pyruvate metabolism" EXACT [] +xref: MetaCyc:P41-PWY +xref: Wikipedia:Pyruvic_acid +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0006091 +name: generation of precursor metabolites and energy +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_pombe +subset: goslim_yeast +synonym: "energy pathways" BROAD [] +synonym: "intermediary metabolism" RELATED [GOC:mah] +synonym: "metabolic energy generation" RELATED [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0006094 +name: gluconeogenesis +namespace: biological_process +def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY] +synonym: "glucose biosynthesis" EXACT [] +synonym: "glucose biosynthetic process" EXACT [] +xref: MetaCyc:GLUCONEO-PWY +xref: Wikipedia:Gluconeogenesis +is_a: GO:0006006 ! glucose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0006096 +name: glycolytic process +namespace: biological_process +alt_id: GO:0019641 +alt_id: GO:0019642 +def: "The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules." [GOC:bf, GOC:dph, ISBN:0201090910, ISBN:0716720094, ISBN:0879010479, Wikipedia:Glycolysis] +synonym: "anaerobic glycolysis" RELATED [] +synonym: "Embden-Meyerhof pathway" RELATED [] +synonym: "Embden-Meyerhof-Parnas pathway" RELATED [] +synonym: "glycolysis" RELATED [GOC:dph] +synonym: "modifed Embden-Meyerhof pathway" RELATED [] +xref: MetaCyc:GLYCOLYSIS-VARIANTS +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0006757 ! ATP generation from ADP +is_a: GO:0016052 ! carbohydrate catabolic process +relationship: has_part GO:0004618 ! phosphoglycerate kinase activity +relationship: has_part GO:0004619 ! phosphoglycerate mutase activity +relationship: has_part GO:0004634 ! phosphopyruvate hydratase activity +relationship: has_part GO:0043891 ! glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity + +[Term] +id: GO:0006097 +name: glyoxylate cycle +namespace: biological_process +def: "A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate." [ISBN:0198506732] +synonym: "glyoxylate bypass" EXACT [] +xref: MetaCyc:GLYOXYLATE-BYPASS +xref: Wikipedia:Glyoxylate_cycle +is_a: GO:0044262 ! cellular carbohydrate metabolic process +is_a: GO:0046487 ! glyoxylate metabolic process + +[Term] +id: GO:0006098 +name: pentose-phosphate shunt +namespace: biological_process +def: "The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate)." [GOC:pde, ISBN:0198506732, MetaCyc:PENTOSE-P-PWY] +synonym: "hexose monophosphate pathway" EXACT [] +synonym: "pentose phosphate pathway" EXACT [] +synonym: "pentose phosphate shunt" EXACT [] +synonym: "pentose-phosphate pathway" EXACT [] +xref: KEGG_PATHWAY:00030 +xref: MetaCyc:PENTOSE-P-PWY +xref: Reactome:R-HSA-71336 "Pentose phosphate pathway (hexose monophosphate shunt), Homo sapiens" +xref: Wikipedia:Pentose_phosphate_pathway +is_a: GO:0006740 ! NADPH regeneration +is_a: GO:0051156 ! glucose 6-phosphate metabolic process + +[Term] +id: GO:0006099 +name: tricarboxylic acid cycle +namespace: biological_process +def: "A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle." [ISBN:0198506732] +synonym: "citric acid cycle" EXACT [] +synonym: "Krebs cycle" EXACT [] +synonym: "TCA cycle" EXACT [] +xref: MetaCyc:P105-PWY +xref: MetaCyc:P42-PWY +xref: MetaCyc:TCA +xref: Wikipedia:Tricarboxylic_acid_cycle +is_a: GO:0044238 ! primary metabolic process +relationship: part_of GO:0009060 ! aerobic respiration + +[Term] +id: GO:0006100 +name: obsolete tricarboxylic acid cycle intermediate metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle." [GOC:ai] +comment: This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations. +synonym: "citric acid cycle intermediate metabolic process" EXACT [] +synonym: "citric acid cycle intermediate metabolism" EXACT [] +synonym: "Krebs cycle intermediate metabolic process" EXACT [] +synonym: "Krebs cycle intermediate metabolism" EXACT [] +synonym: "TCA intermediate metabolic process" EXACT [] +synonym: "TCA intermediate metabolism" EXACT [] +synonym: "tricarboxylic acid cycle intermediate metabolic process" EXACT [] +synonym: "tricarboxylic acid cycle intermediate metabolism" EXACT [] +is_obsolete: true +consider: GO:0006099 +consider: GO:0006101 +consider: GO:0006103 +consider: GO:0006104 +consider: GO:0006105 +consider: GO:0006106 +consider: GO:0006107 +consider: GO:0006108 + +[Term] +id: GO:0006101 +name: citrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle." [ISBN:0198506732] +synonym: "citrate metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process + +[Term] +id: GO:0006102 +name: isocitrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle." [ISBN:0198506732] +synonym: "isocitrate metabolism" EXACT [] +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0006103 +name: 2-oxoglutarate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism." [ISBN:0198506732] +synonym: "2-ketoglutarate metabolic process" EXACT [] +synonym: "2-ketoglutarate metabolism" EXACT [] +synonym: "2-oxoglutarate metabolism" EXACT [] +synonym: "alpha-ketoglutarate metabolic process" EXACT [] +synonym: "alpha-ketoglutarate metabolism" EXACT [] +synonym: "alpha-oxoglutarate metabolic process" EXACT [] +synonym: "alpha-oxoglutarate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006104 +name: succinyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A." [GOC:ai] +synonym: "succinyl-CoA metabolism" EXACT [] +is_a: GO:0006637 ! acyl-CoA metabolic process + +[Term] +id: GO:0006105 +name: succinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle." [ISBN:0198506732] +synonym: "succinate metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006106 +name: fumarate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate." [ISBN:0198506732] +synonym: "fumarate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006107 +name: oxaloacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle." [ISBN:0198506732] +synonym: "oxaloacetate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006108 +name: malate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle." [ISBN:0198506732] +synonym: "malate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006109 +name: regulation of carbohydrate metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators] +synonym: "regulation of carbohydrate metabolism" EXACT [] +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005975 ! carbohydrate metabolic process +relationship: regulates GO:0005975 ! carbohydrate metabolic process + +[Term] +id: GO:0006110 +name: regulation of glycolytic process +namespace: biological_process +alt_id: GO:0090525 +def: "Any process that modulates the frequency, rate or extent of glycolysis." [GOC:go_curators] +synonym: "regulation of glycolysis involved in cellular glucose homeostasis" EXACT [] +is_a: GO:0042325 ! regulation of phosphorylation +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006096 ! glycolytic process +relationship: regulates GO:0006096 ! glycolytic process + +[Term] +id: GO:0006111 +name: regulation of gluconeogenesis +namespace: biological_process +alt_id: GO:0090526 +def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] +synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED [] +synonym: "regulation of glucose biosynthesis" BROAD [] +synonym: "regulation of glucose biosynthetic process" BROAD [] +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006094 ! gluconeogenesis +relationship: regulates GO:0006094 ! gluconeogenesis +created_by: tb +creation_date: 2013-01-18T12:47:43Z + +[Term] +id: GO:0006112 +name: energy reserve metabolic process +namespace: biological_process +def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah] +subset: goslim_pir +synonym: "energy reserve metabolism" EXACT [] +is_a: GO:0015980 ! energy derivation by oxidation of organic compounds + +[Term] +id: GO:0006113 +name: fermentation +namespace: biological_process +def: "The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)." [GOC:curators, ISBN:0201090910, MetaCyc:Fermentation] +subset: goslim_pir +xref: MetaCyc:FERMENTATION-PWY +xref: Wikipedia:Fermentation_(biochemistry) +is_a: GO:0015980 ! energy derivation by oxidation of organic compounds + +[Term] +id: GO:0006114 +name: glycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:ai, ISBN:0198506732] +synonym: "glycerol anabolism" EXACT [] +synonym: "glycerol biosynthesis" EXACT [] +synonym: "glycerol formation" EXACT [] +synonym: "glycerol synthesis" EXACT [] +is_a: GO:0006071 ! glycerol metabolic process +is_a: GO:0019401 ! alditol biosynthetic process + +[Term] +id: GO:0006115 +name: ethanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation." [GOC:ai, ISBN:0198506732] +synonym: "ethanol anabolism" EXACT [] +synonym: "ethanol biosynthesis" EXACT [] +synonym: "ethanol formation" EXACT [] +synonym: "ethanol synthesis" EXACT [] +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process + +[Term] +id: GO:0006116 +name: NADH oxidation +namespace: biological_process +def: "A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD." [GOC:ai] +synonym: "NAD (reduced) dehydrogenation" EXACT [] +synonym: "NAD (reduced) oxidation" EXACT [] +synonym: "NADH dehydrogenation" EXACT [] +synonym: "reduced NAD dehydrogenation" EXACT [] +synonym: "reduced NAD oxidation" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide dehydrogenation" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide oxidation" EXACT [] +is_a: GO:0006734 ! NADH metabolic process +is_a: GO:0019674 ! NAD metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006117 +name: acetaldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol." [GOC:go_curators] +synonym: "acetaldehyde metabolism" EXACT [] +synonym: "ethanal metabolic process" EXACT [] +synonym: "ethanal metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process + +[Term] +id: GO:0006118 +name: obsolete electron transport +namespace: biological_process +def: "OBSOLETE. The transport of electrons from an electron donor to an electron acceptor." [GOC:curators] +comment: This term was made obsolete because it describes a molecular function. +synonym: "6-phosphofructokinase reduction" RELATED [] +synonym: "dihydrobiopterin reduction" RELATED [] +synonym: "dihydrolipoamide reduction" RELATED [] +synonym: "dihydrolipoylprotein reduction" RELATED [] +synonym: "dihydropteridine reduction" RELATED [] +synonym: "electron transfer" EXACT [] +synonym: "electron transport" EXACT [] +synonym: "other pathways of electron transport" RELATED [] +synonym: "oxidized glutathione reduction" RELATED [] +synonym: "protein-disulfide reduction" RELATED [] +is_obsolete: true +replaced_by: GO:0055114 +consider: GO:0016491 +consider: GO:0022904 + +[Term] +id: GO:0006119 +name: oxidative phosphorylation +namespace: biological_process +def: "The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis." [ISBN:0198506732, ISBN:0471331309] +subset: goslim_pir +synonym: "respiratory-chain phosphorylation" EXACT [] +xref: Wikipedia:Oxidative_phosphorylation +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0016310 ! phosphorylation +is_a: GO:0046034 ! ATP metabolic process +relationship: has_part GO:0015986 ! ATP synthesis coupled proton transport + +[Term] +id: GO:0006120 +name: mitochondrial electron transport, NADH to ubiquinone +namespace: biological_process +def: "The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I." [ISBN:0716731363] +synonym: "complex I (NADH to ubiquinone)" RELATED [] +synonym: "oxidative phosphorylation, NADH to ubiquinone" EXACT [] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0042775 ! mitochondrial ATP synthesis coupled electron transport + +[Term] +id: GO:0006121 +name: mitochondrial electron transport, succinate to ubiquinone +namespace: biological_process +def: "The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II." [ISBN:0716731363] +synonym: "complex II (succinate to ubiquinone)" RELATED [] +synonym: "mitochondrial electron transport, succinate to coenzyme Q" EXACT [] +synonym: "oxidative phosphorylation, succinate to ubiquinone" EXACT [] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0042775 ! mitochondrial ATP synthesis coupled electron transport + +[Term] +id: GO:0006122 +name: mitochondrial electron transport, ubiquinol to cytochrome c +namespace: biological_process +def: "The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III." [ISBN:0716731363] +synonym: "complex III (ubiquinone to cytochrome c)" RELATED [] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0042775 ! mitochondrial ATP synthesis coupled electron transport + +[Term] +id: GO:0006123 +name: mitochondrial electron transport, cytochrome c to oxygen +namespace: biological_process +def: "The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV." [ISBN:0716731363] +synonym: "complex IV (reduction of O2)" RELATED [] +is_a: GO:0019646 ! aerobic electron transport chain +relationship: part_of GO:0042775 ! mitochondrial ATP synthesis coupled electron transport + +[Term] +id: GO:0006124 +name: ferredoxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each." [ISBN:0198506732] +synonym: "ferredoxin metabolism" EXACT [] +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0006125 +name: obsolete thioredoxin pathway +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_electron_transport] +comment: This term was made obsolete because it is not clear what it is intended to represent. +synonym: "thioredoxin pathway" EXACT [] +synonym: "thioredoxin reduction" NARROW [] +xref: MetaCyc:THIOREDOX-PWY +is_obsolete: true +consider: GO:0045454 + +[Term] +id: GO:0006126 +name: obsolete other pathways of electron transport +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other pathways of electron transport" EXACT [] +is_obsolete: true +replaced_by: GO:0022900 + +[Term] +id: GO:0006127 +name: glycerophosphate shuttle +namespace: biological_process +def: "The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle." [GOC:jl, GOC:mtg_electron_transport, ISBN:0716720094, PMID:16368075] +xref: MetaCyc:PWY-6118 +is_a: GO:0006116 ! NADH oxidation +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +relationship: has_part GO:0004367 ! glycerol-3-phosphate dehydrogenase [NAD+] activity +relationship: has_part GO:0052590 ! sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity +relationship: part_of GO:0022904 ! respiratory electron transport chain + +[Term] +id: GO:0006128 +name: obsolete oxidized glutathione reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the term string represents a molecular function and not a biological pathway. +synonym: "oxidized glutathione reduction" EXACT [] +is_obsolete: true +consider: GO:0004362 +consider: GO:0006749 +consider: GO:0022900 + +[Term] +id: GO:0006129 +name: obsolete protein-disulfide reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "protein-disulfide reduction" EXACT [] +synonym: "protein-disulphide reduction" EXACT [] +is_obsolete: true +consider: GO:0019153 +consider: GO:0022900 + +[Term] +id: GO:0006130 +name: obsolete 6-phosphofructokinase reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the term string was ambiguous and the term may represent a molecular function. +synonym: "6-phosphofructokinase reduction" EXACT [] +is_obsolete: true +consider: GO:0003872 +consider: GO:0022900 + +[Term] +id: GO:0006131 +name: obsolete dihydrolipoamide reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "dihydrolipoamide reduction" EXACT [] +is_obsolete: true +consider: GO:0004148 +consider: GO:0022900 +consider: GO:0051068 + +[Term] +id: GO:0006132 +name: obsolete dihydrolipoylprotein reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "dihydrolipoylprotein reduction" EXACT [] +is_obsolete: true +consider: GO:0004148 +consider: GO:0022900 + +[Term] +id: GO:0006133 +name: obsolete 5,10-methylenetetrahydrofolate oxidation +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_electron_transport] +comment: This term was made obsolete because it is defined as a function term and is in the process ontology. +synonym: "5,10-methylenetetrahydrofolate oxidation" EXACT [] +is_obsolete: true +consider: GO:0004487 +consider: GO:0004488 +consider: GO:0004489 +consider: GO:0033738 + +[Term] +id: GO:0006134 +name: obsolete dihydrobiopterin reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "dihydrobiopterin reduction" EXACT [] +is_obsolete: true +consider: GO:0022900 +consider: GO:0047040 +consider: GO:0051066 + +[Term] +id: GO:0006135 +name: obsolete dihydropteridine reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "dihydropteridine reduction" EXACT [] +is_obsolete: true +consider: GO:0004155 +consider: GO:0022900 +consider: GO:0051067 + +[Term] +id: GO:0006139 +name: nucleobase-containing compound metabolic process +namespace: biological_process +alt_id: GO:0055134 +def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] +subset: goslim_pir +subset: goslim_plant +synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0044238 ! primary metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0006140 +name: regulation of nucleotide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] +synonym: "regulation of nucleotide metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0019220 ! regulation of phosphate metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009117 ! nucleotide metabolic process +relationship: regulates GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0006141 +name: regulation of purine nucleobase metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines." [GOC:go_curators] +synonym: "regulation of purine base metabolic process" EXACT [GOC:go_curators] +synonym: "regulation of purine base metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006144 ! purine nucleobase metabolic process +relationship: regulates GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0006142 +name: regulation of pyrimidine nucleobase metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases." [GOC:go_curators] +synonym: "regulation of pyrimidine base metabolic process" EXACT [GOC:go_curators] +synonym: "regulation of pyrimidine base metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006206 ! pyrimidine nucleobase metabolic process +relationship: regulates GO:0006206 ! pyrimidine nucleobase metabolic process + +[Term] +id: GO:0006143 +name: obsolete purine metabolic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "purine metabolic process" EXACT [] +is_obsolete: true +consider: GO:0006144 +consider: GO:0006163 +consider: GO:0042278 + +[Term] +id: GO:0006144 +name: purine nucleobase metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine." [GOC:go_curators] +synonym: "purine base metabolic process" EXACT [GOC:go_curators] +synonym: "purine base metabolism" EXACT [] +synonym: "purine metabolic process" NARROW [] +synonym: "purine metabolism" NARROW [] +is_a: GO:0009112 ! nucleobase metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0006145 +name: purine nucleobase catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine." [GOC:go_curators] +synonym: "purine base breakdown" EXACT [] +synonym: "purine base catabolic process" EXACT [GOC:go_curators] +synonym: "purine base catabolism" EXACT [] +synonym: "purine base degradation" EXACT [] +is_a: GO:0006144 ! purine nucleobase metabolic process +is_a: GO:0046113 ! nucleobase catabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0006146 +name: adenine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine." [ISBN:0198506732] +synonym: "adenine breakdown" EXACT [] +synonym: "adenine catabolism" EXACT [] +synonym: "adenine degradation" EXACT [] +is_a: GO:0006145 ! purine nucleobase catabolic process +is_a: GO:0046083 ! adenine metabolic process + +[Term] +id: GO:0006147 +name: guanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important." [GOC:go_curators] +synonym: "guanine breakdown" EXACT [] +synonym: "guanine catabolism" EXACT [] +synonym: "guanine degradation" EXACT [] +is_a: GO:0006145 ! purine nucleobase catabolic process +is_a: GO:0046098 ! guanine metabolic process + +[Term] +id: GO:0006148 +name: inosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs." [GOC:go_curators] +synonym: "inosine breakdown" EXACT [] +synonym: "inosine catabolism" EXACT [] +synonym: "inosine degradation" EXACT [] +is_a: GO:0046102 ! inosine metabolic process +is_a: GO:0046130 ! purine ribonucleoside catabolic process + +[Term] +id: GO:0006149 +name: deoxyinosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside." [GOC:go_curators] +synonym: "deoxyinosine breakdown" EXACT [] +synonym: "deoxyinosine catabolism" EXACT [] +synonym: "deoxyinosine degradation" EXACT [] +is_a: GO:0046094 ! deoxyinosine metabolic process +is_a: GO:0046124 ! purine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006150 +name: hypoxanthine oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hypoxanthine to xanthine and thence to uric acid." [GOC:mah, PMID:3196295] +is_a: GO:0009114 ! hypoxanthine catabolic process +relationship: has_part GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006151 +name: xanthine oxidation +namespace: biological_process +def: "The oxidation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids." [GOC:jl] +is_a: GO:0009115 ! xanthine catabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006152 +name: purine nucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:go_curators] +synonym: "purine nucleoside breakdown" EXACT [] +synonym: "purine nucleoside catabolism" EXACT [] +synonym: "purine nucleoside degradation" EXACT [] +is_a: GO:0009164 ! nucleoside catabolic process +is_a: GO:0042278 ! purine nucleoside metabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0006153 +name: obsolete purine nucleosidase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "purine nucleosidase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0008477 + +[Term] +id: GO:0006154 +name: adenosine catabolic process +namespace: biological_process +alt_id: GO:0006156 +def: "The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes." [GOC:go_curators] +synonym: "adenosine breakdown" EXACT [] +synonym: "adenosine catabolism" EXACT [] +synonym: "adenosine degradation" EXACT [] +synonym: "adenosine phosphorolysis" RELATED [] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046085 ! adenosine metabolic process +is_a: GO:0046130 ! purine ribonucleoside catabolic process + +[Term] +id: GO:0006155 +name: obsolete adenosine deaminase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "adenosine deaminase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0004000 + +[Term] +id: GO:0006157 +name: deoxyadenosine catabolic process +namespace: biological_process +alt_id: GO:0006159 +def: "The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyadenosine breakdown" EXACT [] +synonym: "deoxyadenosine catabolism" EXACT [] +synonym: "deoxyadenosine degradation" EXACT [] +synonym: "deoxyadenosine phosphorolysis" RELATED [] +is_a: GO:0046090 ! deoxyadenosine metabolic process +is_a: GO:0046124 ! purine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006158 +name: obsolete deoxyadenosine deaminase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "deoxyadenosine deaminase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0046936 + +[Term] +id: GO:0006161 +name: deoxyguanosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose." [GOC:jl] +synonym: "deoxyguanosine breakdown" EXACT [] +synonym: "deoxyguanosine catabolism" EXACT [] +synonym: "deoxyguanosine degradation" EXACT [] +is_a: GO:0042453 ! deoxyguanosine metabolic process +is_a: GO:0046124 ! purine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006162 +name: obsolete purine/pyrimidine nucleoside diphosphate reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "purine/pyrimidine nucleoside diphosphate reduction" EXACT [] +is_obsolete: true +consider: GO:0004748 + +[Term] +id: GO:0006163 +name: purine nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine metabolic process" NARROW [] +synonym: "purine metabolism" NARROW [] +synonym: "purine nucleotide metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0006164 +name: purine nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleotide anabolism" EXACT [] +synonym: "purine nucleotide biosynthesis" EXACT [] +synonym: "purine nucleotide formation" EXACT [] +synonym: "purine nucleotide synthesis" EXACT [] +xref: MetaCyc:DENOVOPURINE2-PWY +is_a: GO:0006163 ! purine nucleotide metabolic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0006165 +name: nucleoside diphosphate phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate." [GOC:ai] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0009132 ! nucleoside diphosphate metabolic process +is_a: GO:0046939 ! nucleotide phosphorylation + +[Term] +id: GO:0006166 +name: purine ribonucleoside salvage +namespace: biological_process +def: "Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis." [GOC:jl] +xref: MetaCyc:P121-PWY +is_a: GO:0043101 ! purine-containing compound salvage +is_a: GO:0043174 ! nucleoside salvage +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process + +[Term] +id: GO:0006167 +name: AMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate." [GOC:go_curators, ISBN:0198506732] +synonym: "AMP anabolism" EXACT [] +synonym: "AMP biosynthesis" EXACT [] +synonym: "AMP formation" EXACT [] +synonym: "AMP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009168 ! purine ribonucleoside monophosphate biosynthetic process +is_a: GO:0046033 ! AMP metabolic process + +[Term] +id: GO:0006168 +name: adenine salvage +namespace: biological_process +def: "Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "adenine salvage pathway" EXACT [] +synonym: "adenine, hypoxanthine and their nucleoside salvage" BROAD [] +is_a: GO:0043096 ! purine nucleobase salvage +is_a: GO:0046084 ! adenine biosynthetic process + +[Term] +id: GO:0006169 +name: adenosine salvage +namespace: biological_process +def: "Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "adenine, hypoxanthine and their nucleoside salvage" BROAD [] +is_a: GO:0006166 ! purine ribonucleoside salvage +is_a: GO:0046086 ! adenosine biosynthetic process + +[Term] +id: GO:0006170 +name: dAMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)." [ISBN:0198506732] +synonym: "dAMP anabolism" EXACT [] +synonym: "dAMP biosynthesis" EXACT [] +synonym: "dAMP formation" EXACT [] +synonym: "dAMP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009171 ! purine deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0046053 ! dAMP metabolic process + +[Term] +id: GO:0006171 +name: cAMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [ISBN:0198506732] +synonym: "3',5' cAMP biosynthesis" EXACT [] +synonym: "3',5' cAMP biosynthetic process" EXACT [] +synonym: "3',5'-cAMP biosynthesis" EXACT [] +synonym: "3',5'-cAMP biosynthetic process" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] +synonym: "cAMP anabolism" EXACT [] +synonym: "cAMP biosynthesis" EXACT [] +synonym: "cAMP formation" EXACT [] +synonym: "cAMP synthesis" EXACT [] +synonym: "cyclic AMP biosynthesis" EXACT [] +synonym: "cyclic AMP biosynthetic process" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0046058 ! cAMP metabolic process +is_a: GO:0052652 ! cyclic purine nucleotide metabolic process + +[Term] +id: GO:0006172 +name: ADP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate." [GOC:ai] +synonym: "ADP anabolism" EXACT [] +synonym: "ADP biosynthesis" EXACT [] +synonym: "ADP formation" EXACT [] +synonym: "ADP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009180 ! purine ribonucleoside diphosphate biosynthetic process +is_a: GO:0046031 ! ADP metabolic process + +[Term] +id: GO:0006173 +name: dADP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)." [ISBN:0198506732] +synonym: "dADP anabolism" EXACT [] +synonym: "dADP biosynthesis" EXACT [] +synonym: "dADP formation" EXACT [] +synonym: "dADP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009183 ! purine deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0046056 ! dADP metabolic process + +[Term] +id: GO:0006174 +name: dADP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP." [ISBN:0198506732] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +is_a: GO:0009216 ! purine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0046056 ! dADP metabolic process + +[Term] +id: GO:0006175 +name: dATP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)." [ISBN:0198506732] +synonym: "dATP anabolism" EXACT [] +synonym: "dATP biosynthesis" EXACT [] +synonym: "dATP formation" EXACT [] +synonym: "dATP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009216 ! purine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0046060 ! dATP metabolic process + +[Term] +id: GO:0006176 +name: dATP biosynthetic process from ADP +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate." [ISBN:0198506732] +synonym: "dATP anabolism from ADP" EXACT [] +synonym: "dATP formation from ADP" EXACT [] +synonym: "dATP synthesis from ADP" EXACT [] +is_a: GO:0006175 ! dATP biosynthetic process +is_a: GO:0046031 ! ADP metabolic process + +[Term] +id: GO:0006177 +name: GMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate." [ISBN:0198506732] +synonym: "GMP anabolism" EXACT [] +synonym: "GMP biosynthesis" EXACT [] +synonym: "GMP formation" EXACT [] +synonym: "GMP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009168 ! purine ribonucleoside monophosphate biosynthetic process +is_a: GO:0046037 ! GMP metabolic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0006178 +name: guanine salvage +namespace: biological_process +def: "Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "guanine, xanthine and their nucleoside salvage" BROAD [] +is_a: GO:0043096 ! purine nucleobase salvage +is_a: GO:0046099 ! guanine biosynthetic process + +[Term] +id: GO:0006179 +name: guanosine salvage +namespace: biological_process +def: "Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "guanine, xanthine and their nucleoside salvage" BROAD [] +is_a: GO:0006166 ! purine ribonucleoside salvage +is_a: GO:0046114 ! guanosine biosynthetic process + +[Term] +id: GO:0006180 +name: deoxyguanosine salvage +namespace: biological_process +def: "Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0043098 ! purine deoxyribonucleoside salvage + +[Term] +id: GO:0006181 +name: dGMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)." [ISBN:0198506732] +synonym: "dGMP anabolism" EXACT [] +synonym: "dGMP biosynthesis" EXACT [] +synonym: "dGMP formation" EXACT [] +synonym: "dGMP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009171 ! purine deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0046054 ! dGMP metabolic process + +[Term] +id: GO:0006182 +name: cGMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate." [ISBN:0198506732] +synonym: "cGMP anabolism" EXACT [] +synonym: "cGMP biosynthesis" EXACT [] +synonym: "cGMP formation" EXACT [] +synonym: "cGMP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0046068 ! cGMP metabolic process +is_a: GO:0052652 ! cyclic purine nucleotide metabolic process + +[Term] +id: GO:0006183 +name: GTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate." [ISBN:0198506732] +synonym: "GTP anabolism" EXACT [] +synonym: "GTP biosynthesis" EXACT [] +synonym: "GTP formation" EXACT [] +synonym: "GTP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009206 ! purine ribonucleoside triphosphate biosynthetic process +is_a: GO:0046039 ! GTP metabolic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0006184 +name: obsolete GTP catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [ISBN:0198506732] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "GTP breakdown" EXACT [] +synonym: "GTP catabolism" EXACT [] +synonym: "GTP degradation" EXACT [] +synonym: "GTP hydrolysis" NARROW [] +is_obsolete: true +consider: GO:0003924 + +[Term] +id: GO:0006185 +name: dGDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)." [ISBN:0198506732] +synonym: "dGDP anabolism" EXACT [] +synonym: "dGDP biosynthesis" EXACT [] +synonym: "dGDP formation" EXACT [] +synonym: "dGDP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009183 ! purine deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0046066 ! dGDP metabolic process + +[Term] +id: GO:0006186 +name: dGDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP." [ISBN:0198506732] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +is_a: GO:0009216 ! purine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0046066 ! dGDP metabolic process + +[Term] +id: GO:0006187 +name: dGTP biosynthetic process from dGDP +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate." [ISBN:0198506732] +synonym: "dGTP anabolism from dGDP" EXACT [] +synonym: "dGTP formation from dGDP" EXACT [] +synonym: "dGTP synthesis from dGDP" EXACT [] +is_a: GO:0046066 ! dGDP metabolic process +is_a: GO:0046071 ! dGTP biosynthetic process + +[Term] +id: GO:0006188 +name: IMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate." [ISBN:0198506732] +synonym: "IMP anabolism" EXACT [] +synonym: "IMP biosynthesis" EXACT [] +synonym: "IMP formation" EXACT [] +synonym: "IMP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009168 ! purine ribonucleoside monophosphate biosynthetic process +is_a: GO:0046040 ! IMP metabolic process + +[Term] +id: GO:0006189 +name: 'de novo' IMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate." [GOC:mah, ISBN:0716720094] +synonym: "'de novo' IMP anabolism" EXACT [] +synonym: "'de novo' IMP biosynthesis" EXACT [] +synonym: "'de novo' IMP formation" EXACT [] +synonym: "'de novo' IMP synthesis" EXACT [] +synonym: "'de novo' purine biosynthesis" BROAD [] +synonym: "'de novo' purine biosynthetic process" BROAD [] +is_a: GO:0006188 ! IMP biosynthetic process + +[Term] +id: GO:0006190 +name: inosine salvage +namespace: biological_process +def: "Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "adenine, hypoxanthine and their nucleoside salvage" RELATED [] +synonym: "guanine, xanthine and their nucleoside salvage" RELATED [] +is_a: GO:0006166 ! purine ribonucleoside salvage +is_a: GO:0046103 ! inosine biosynthetic process + +[Term] +id: GO:0006191 +name: deoxyinosine salvage +namespace: biological_process +def: "Any process that generates deoxyinosine from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0043098 ! purine deoxyribonucleoside salvage +is_a: GO:0046095 ! deoxyinosine biosynthetic process + +[Term] +id: GO:0006192 +name: IDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP." [GOC:ai] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +is_a: GO:0009206 ! purine ribonucleoside triphosphate biosynthetic process +is_a: GO:0046707 ! IDP metabolic process + +[Term] +id: GO:0006193 +name: ITP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate." [ISBN:0198506732] +synonym: "ITP breakdown" EXACT [] +synonym: "ITP catabolism" EXACT [] +synonym: "ITP degradation" EXACT [] +synonym: "ITP hydrolysis" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009207 ! purine ribonucleoside triphosphate catabolic process +is_a: GO:0046041 ! ITP metabolic process + +[Term] +id: GO:0006194 +name: dIDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP." [ISBN:0198506732] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +is_a: GO:0009216 ! purine deoxyribonucleoside triphosphate biosynthetic process + +[Term] +id: GO:0006195 +name: purine nucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleotide breakdown" EXACT [] +synonym: "purine nucleotide catabolism" EXACT [] +synonym: "purine nucleotide degradation" EXACT [] +is_a: GO:0006163 ! purine nucleotide metabolic process +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0006196 +name: AMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate." [ISBN:0198506732] +synonym: "AMP breakdown" EXACT [] +synonym: "AMP catabolism" EXACT [] +synonym: "AMP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009169 ! purine ribonucleoside monophosphate catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046033 ! AMP metabolic process + +[Term] +id: GO:0006197 +name: obsolete adenylate deaminase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "adenylate deaminase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0003876 + +[Term] +id: GO:0006198 +name: cAMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [ISBN:0198506732] +synonym: "3',5' cAMP catabolic process" EXACT [] +synonym: "3',5' cAMP catabolism" EXACT [] +synonym: "3',5'-cAMP catabolic process" EXACT [] +synonym: "3',5'-cAMP catabolism" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate catabolic process" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate catabolism" EXACT [] +synonym: "cAMP breakdown" EXACT [] +synonym: "cAMP catabolism" EXACT [] +synonym: "cAMP degradation" EXACT [] +synonym: "cyclic AMP catabolic process" EXACT [] +synonym: "cyclic AMP catabolism" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009214 ! cyclic nucleotide catabolic process +is_a: GO:0046058 ! cAMP metabolic process + +[Term] +id: GO:0006199 +name: obsolete ADP reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "ADP reduction" EXACT [] +is_obsolete: true +consider: GO:0051061 + +[Term] +id: GO:0006200 +name: obsolete ATP catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [GOC:ai] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "ATP breakdown" EXACT [] +synonym: "ATP catabolism" EXACT [] +synonym: "ATP degradation" EXACT [] +synonym: "ATP hydrolysis" NARROW [] +xref: Wikipedia:ATP_hydrolysis +is_obsolete: true +consider: GO:0016887 + +[Term] +id: GO:0006201 +name: GMP catabolic process to IMP +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate." [ISBN:0198506732] +synonym: "GMP breakdown to IMP" EXACT [] +synonym: "GMP degradation to IMP" EXACT [] +is_a: GO:0006188 ! IMP biosynthetic process +is_a: GO:0046038 ! GMP catabolic process + +[Term] +id: GO:0006202 +name: GMP catabolic process to guanine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine." [ISBN:0198506732] +synonym: "GMP breakdown to guanine" EXACT [] +synonym: "GMP degradation to guanine" EXACT [] +is_a: GO:0046038 ! GMP catabolic process +is_a: GO:0046099 ! guanine biosynthetic process + +[Term] +id: GO:0006203 +name: dGTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate." [ISBN:0198506732] +synonym: "dGTP breakdown" EXACT [] +synonym: "dGTP catabolism" EXACT [] +synonym: "dGTP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009217 ! purine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0046070 ! dGTP metabolic process + +[Term] +id: GO:0006204 +name: IMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate." [ISBN:0198506732] +synonym: "IMP breakdown" EXACT [] +synonym: "IMP catabolism" EXACT [] +synonym: "IMP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009169 ! purine ribonucleoside monophosphate catabolic process +is_a: GO:0046040 ! IMP metabolic process + +[Term] +id: GO:0006205 +name: obsolete pyrimidine metabolic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "pyrimidine metabolic process" EXACT [] +is_obsolete: true +consider: GO:0006206 +consider: GO:0006213 +consider: GO:0006220 + +[Term] +id: GO:0006206 +name: pyrimidine nucleobase metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." [GOC:go_curators] +synonym: "pyrimidine base metabolic process" EXACT [GOC:go_curators] +synonym: "pyrimidine base metabolism" EXACT [] +synonym: "pyrimidine metabolic process" RELATED [] +synonym: "pyrimidine metabolism" RELATED [] +is_a: GO:0009112 ! nucleobase metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0006207 +name: 'de novo' pyrimidine nucleobase biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors." [GOC:mah, ISBN:0716720094] +synonym: "'de novo' pyrimidine base anabolism" EXACT [] +synonym: "'de novo' pyrimidine base biosynthesis" EXACT [] +synonym: "'de novo' pyrimidine base biosynthetic process" EXACT [GOC:go_curators] +synonym: "'de novo' pyrimidine base formation" EXACT [] +synonym: "'de novo' pyrimidine base synthesis" EXACT [] +is_a: GO:0019856 ! pyrimidine nucleobase biosynthetic process + +[Term] +id: GO:0006208 +name: pyrimidine nucleobase catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." [GOC:go_curators] +synonym: "pyrimidine base breakdown" EXACT [] +synonym: "pyrimidine base catabolic process" EXACT [GOC:go_curators] +synonym: "pyrimidine base catabolism" EXACT [] +synonym: "pyrimidine base degradation" EXACT [] +is_a: GO:0006206 ! pyrimidine nucleobase metabolic process +is_a: GO:0046113 ! nucleobase catabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0006209 +name: cytosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives." [GOC:go_curators] +synonym: "cytosine breakdown" EXACT [] +synonym: "cytosine catabolism" EXACT [] +synonym: "cytosine degradation" EXACT [] +is_a: GO:0006208 ! pyrimidine nucleobase catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0019858 ! cytosine metabolic process + +[Term] +id: GO:0006210 +name: thymine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base." [GOC:go_curators] +synonym: "thymine breakdown" EXACT [] +synonym: "thymine catabolism" EXACT [] +synonym: "thymine degradation" EXACT [] +is_a: GO:0006208 ! pyrimidine nucleobase catabolic process +is_a: GO:0019859 ! thymine metabolic process + +[Term] +id: GO:0006211 +name: 5-methylcytosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA." [GOC:go_curators] +synonym: "5-methylcytosine breakdown" EXACT [] +synonym: "5-methylcytosine catabolism" EXACT [] +synonym: "5-methylcytosine degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0019857 ! 5-methylcytosine metabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0006212 +name: uracil catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA." [GOC:go_curators] +synonym: "uracil breakdown" EXACT [] +synonym: "uracil catabolism" EXACT [] +synonym: "uracil degradation" EXACT [] +is_a: GO:0006208 ! pyrimidine nucleobase catabolic process +is_a: GO:0019860 ! uracil metabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0006213 +name: pyrimidine nucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713] +synonym: "pyrimidine metabolic process" BROAD [] +synonym: "pyrimidine metabolism" BROAD [] +synonym: "pyrimidine nucleoside metabolism" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0006214 +name: thymidine catabolic process +namespace: biological_process +alt_id: GO:0006215 +def: "The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA." [GOC:go_curators] +synonym: "deoxyribosylthymine catabolic process" EXACT [] +synonym: "deoxyribosylthymine catabolism" EXACT [] +synonym: "thymidine breakdown" EXACT [] +synonym: "thymidine catabolism" EXACT [] +synonym: "thymidine degradation" EXACT [] +is_a: GO:0046104 ! thymidine metabolic process +is_a: GO:0046127 ! pyrimidine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006216 +name: cytidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside." [GOC:ai] +synonym: "cytidine breakdown" EXACT [] +synonym: "cytidine catabolism" EXACT [] +synonym: "cytidine degradation" EXACT [] +is_a: GO:0046087 ! cytidine metabolic process +is_a: GO:0046133 ! pyrimidine ribonucleoside catabolic process + +[Term] +id: GO:0006217 +name: deoxycytidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxycytidine breakdown" EXACT [] +synonym: "deoxycytidine catabolism" EXACT [] +synonym: "deoxycytidine degradation" EXACT [] +is_a: GO:0046092 ! deoxycytidine metabolic process +is_a: GO:0046127 ! pyrimidine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006218 +name: uridine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids." [GOC:go_curators] +synonym: "uridine breakdown" EXACT [] +synonym: "uridine catabolism" EXACT [] +synonym: "uridine degradation" EXACT [] +is_a: GO:0046108 ! uridine metabolic process +is_a: GO:0046133 ! pyrimidine ribonucleoside catabolic process + +[Term] +id: GO:0006219 +name: deoxyuridine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyuridine breakdown" EXACT [] +synonym: "deoxyuridine catabolism" EXACT [] +synonym: "deoxyuridine degradation" EXACT [] +is_a: GO:0046096 ! deoxyuridine metabolic process +is_a: GO:0046127 ! pyrimidine deoxyribonucleoside catabolic process + +[Term] +id: GO:0006220 +name: pyrimidine nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine metabolic process" BROAD [] +synonym: "pyrimidine metabolism" BROAD [] +synonym: "pyrimidine nucleotide metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0006221 +name: pyrimidine nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleotide anabolism" EXACT [] +synonym: "pyrimidine nucleotide biosynthesis" EXACT [] +synonym: "pyrimidine nucleotide formation" EXACT [] +synonym: "pyrimidine nucleotide synthesis" EXACT [] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process + +[Term] +id: GO:0006222 +name: UMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate." [ISBN:0198506732] +synonym: "UMP anabolism" EXACT [] +synonym: "UMP biosynthesis" EXACT [] +synonym: "UMP formation" EXACT [] +synonym: "UMP synthesis" EXACT [] +is_a: GO:0009174 ! pyrimidine ribonucleoside monophosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046049 ! UMP metabolic process + +[Term] +id: GO:0006223 +name: uracil salvage +namespace: biological_process +def: "Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis." [GOC:jl] +is_a: GO:0043100 ! pyrimidine nucleobase salvage +is_a: GO:0046107 ! uracil biosynthetic process + +[Term] +id: GO:0006224 +name: obsolete uridine kinase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "uridine kinase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0004849 + +[Term] +id: GO:0006225 +name: UDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate." [ISBN:0198506732] +synonym: "UDP anabolism" EXACT [] +synonym: "UDP biosynthesis" EXACT [] +synonym: "UDP formation" EXACT [] +synonym: "UDP synthesis" EXACT [] +is_a: GO:0009194 ! pyrimidine ribonucleoside diphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046048 ! UDP metabolic process + +[Term] +id: GO:0006226 +name: dUMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate)." [ISBN:0198506732] +synonym: "dUMP anabolism" EXACT [] +synonym: "dUMP biosynthesis" EXACT [] +synonym: "dUMP formation" EXACT [] +synonym: "dUMP synthesis" EXACT [] +is_a: GO:0009177 ! pyrimidine deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046078 ! dUMP metabolic process + +[Term] +id: GO:0006227 +name: dUDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate)." [ISBN:0198506732] +synonym: "dUDP anabolism" EXACT [] +synonym: "dUDP biosynthesis" EXACT [] +synonym: "dUDP formation" EXACT [] +synonym: "dUDP synthesis" EXACT [] +is_a: GO:0009197 ! pyrimidine deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046077 ! dUDP metabolic process + +[Term] +id: GO:0006228 +name: UTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate." [ISBN:0198506732] +synonym: "UTP anabolism" EXACT [] +synonym: "UTP biosynthesis" EXACT [] +synonym: "UTP formation" EXACT [] +synonym: "UTP synthesis" EXACT [] +is_a: GO:0009209 ! pyrimidine ribonucleoside triphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046051 ! UTP metabolic process + +[Term] +id: GO:0006229 +name: dUTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate." [ISBN:0198506732] +synonym: "dUTP anabolism" EXACT [] +synonym: "dUTP biosynthesis" EXACT [] +synonym: "dUTP formation" EXACT [] +synonym: "dUTP synthesis" EXACT [] +is_a: GO:0009212 ! pyrimidine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046080 ! dUTP metabolic process + +[Term] +id: GO:0006230 +name: TMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate." [ISBN:0198506732] +synonym: "TMP anabolism" EXACT [] +synonym: "TMP biosynthesis" EXACT [] +synonym: "TMP formation" EXACT [] +synonym: "TMP synthesis" EXACT [] +is_a: GO:0009174 ! pyrimidine ribonucleoside monophosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046044 ! TMP metabolic process + +[Term] +id: GO:0006231 +name: dTMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)." [ISBN:0198506732] +synonym: "dTMP anabolism" EXACT [] +synonym: "dTMP biosynthesis" EXACT [] +synonym: "dTMP formation" EXACT [] +synonym: "dTMP synthesis" EXACT [] +is_a: GO:0009177 ! pyrimidine deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046073 ! dTMP metabolic process + +[Term] +id: GO:0006232 +name: TDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate." [ISBN:0198506732] +synonym: "TDP anabolism" EXACT [] +synonym: "TDP biosynthesis" EXACT [] +synonym: "TDP formation" EXACT [] +synonym: "TDP synthesis" EXACT [] +is_a: GO:0009194 ! pyrimidine ribonucleoside diphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046043 ! TDP metabolic process + +[Term] +id: GO:0006233 +name: dTDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate)." [ISBN:0198506732] +synonym: "dTDP anabolism" EXACT [] +synonym: "dTDP biosynthesis" EXACT [] +synonym: "dTDP formation" EXACT [] +synonym: "dTDP synthesis" EXACT [] +is_a: GO:0009197 ! pyrimidine deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046072 ! dTDP metabolic process + +[Term] +id: GO:0006234 +name: TTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate." [ISBN:0198506732] +synonym: "TTP anabolism" EXACT [] +synonym: "TTP biosynthesis" EXACT [] +synonym: "TTP formation" EXACT [] +synonym: "TTP synthesis" EXACT [] +is_a: GO:0009209 ! pyrimidine ribonucleoside triphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046046 ! TTP metabolic process + +[Term] +id: GO:0006235 +name: dTTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate." [ISBN:0198506732] +synonym: "dTTP anabolism" EXACT [] +synonym: "dTTP biosynthesis" EXACT [] +synonym: "dTTP formation" EXACT [] +synonym: "dTTP synthesis" EXACT [] +is_a: GO:0009212 ! pyrimidine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046075 ! dTTP metabolic process + +[Term] +id: GO:0006236 +name: cytidine salvage +namespace: biological_process +def: "Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis." [GOC:jl] +is_a: GO:0043097 ! pyrimidine nucleoside salvage +is_a: GO:0046088 ! cytidine biosynthetic process + +[Term] +id: GO:0006237 +name: deoxycytidine salvage +namespace: biological_process +def: "Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0043099 ! pyrimidine deoxyribonucleoside salvage +is_a: GO:0046093 ! deoxycytidine biosynthetic process + +[Term] +id: GO:0006238 +name: CMP salvage +namespace: biological_process +def: "Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "cytidine monophosphate salvage" EXACT [] +is_a: GO:0009224 ! CMP biosynthetic process +is_a: GO:0010138 ! pyrimidine ribonucleotide salvage + +[Term] +id: GO:0006239 +name: dCMP salvage +namespace: biological_process +def: "Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis." [GOC:jl] +synonym: "deoxycytidine monophosphate salvage" EXACT [] +is_a: GO:0010139 ! pyrimidine deoxyribonucleotide salvage +is_a: GO:0046064 ! dCMP biosynthetic process + +[Term] +id: GO:0006240 +name: dCDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate." [ISBN:0198506732] +synonym: "dCDP anabolism" EXACT [] +synonym: "dCDP biosynthesis" EXACT [] +synonym: "dCDP formation" EXACT [] +synonym: "dCDP synthesis" EXACT [] +is_a: GO:0009197 ! pyrimidine deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046062 ! dCDP metabolic process + +[Term] +id: GO:0006241 +name: CTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate." [ISBN:0198506732] +synonym: "CTP anabolism" EXACT [] +synonym: "CTP biosynthesis" EXACT [] +synonym: "CTP formation" EXACT [] +synonym: "CTP synthesis" EXACT [] +is_a: GO:0009209 ! pyrimidine ribonucleoside triphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046036 ! CTP metabolic process + +[Term] +id: GO:0006242 +name: dCTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate." [ISBN:0198506732] +synonym: "dCTP anabolism" EXACT [] +synonym: "dCTP biosynthesis" EXACT [] +synonym: "dCTP formation" EXACT [] +synonym: "dCTP synthesis" EXACT [] +is_a: GO:0009212 ! pyrimidine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046065 ! dCTP metabolic process + +[Term] +id: GO:0006244 +name: pyrimidine nucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleotide breakdown" EXACT [] +synonym: "pyrimidine nucleotide catabolism" EXACT [] +synonym: "pyrimidine nucleotide degradation" EXACT [] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0006245 +name: TDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate." [ISBN:0198506732] +synonym: "TDP breakdown" EXACT [] +synonym: "TDP catabolism" EXACT [] +synonym: "TDP degradation" EXACT [] +is_a: GO:0009195 ! pyrimidine ribonucleoside diphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046043 ! TDP metabolic process + +[Term] +id: GO:0006246 +name: dTDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate." [ISBN:0198506732] +synonym: "dTDP breakdown" EXACT [] +synonym: "dTDP catabolism" EXACT [] +synonym: "dTDP degradation" EXACT [] +is_a: GO:0009198 ! pyrimidine deoxyribonucleoside diphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046072 ! dTDP metabolic process + +[Term] +id: GO:0006247 +name: obsolete TTP reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "TTP reduction" EXACT [] +is_obsolete: true +consider: GO:0051064 + +[Term] +id: GO:0006248 +name: CMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate." [ISBN:0198506732] +synonym: "CMP breakdown" EXACT [] +synonym: "CMP catabolism" EXACT [] +synonym: "CMP degradation" EXACT [] +is_a: GO:0009175 ! pyrimidine ribonucleoside monophosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046035 ! CMP metabolic process + +[Term] +id: GO:0006249 +name: dCMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate." [ISBN:0198506732] +synonym: "dCMP breakdown" EXACT [] +synonym: "dCMP catabolism" EXACT [] +synonym: "dCMP degradation" EXACT [] +is_a: GO:0009178 ! pyrimidine deoxyribonucleoside monophosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046063 ! dCMP metabolic process + +[Term] +id: GO:0006250 +name: obsolete CDP reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "CDP reduction" EXACT [] +is_obsolete: true +consider: GO:0051063 + +[Term] +id: GO:0006251 +name: dCDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate." [ISBN:0198506732] +synonym: "dCDP breakdown" EXACT [] +synonym: "dCDP catabolism" EXACT [] +synonym: "dCDP degradation" EXACT [] +is_a: GO:0009198 ! pyrimidine deoxyribonucleoside diphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046062 ! dCDP metabolic process + +[Term] +id: GO:0006252 +name: obsolete CTP reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "CTP reduction" EXACT [] +is_obsolete: true +consider: GO:0051065 + +[Term] +id: GO:0006253 +name: dCTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate." [ISBN:0198506732] +synonym: "dCTP breakdown" EXACT [] +synonym: "dCTP catabolism" EXACT [] +synonym: "dCTP degradation" EXACT [] +is_a: GO:0009213 ! pyrimidine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046065 ! dCTP metabolic process + +[Term] +id: GO:0006254 +name: CTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate." [ISBN:0198506732] +synonym: "CTP breakdown" EXACT [] +synonym: "CTP catabolism" EXACT [] +synonym: "CTP degradation" EXACT [] +synonym: "CTP hydrolysis" EXACT [] +is_a: GO:0009210 ! pyrimidine ribonucleoside triphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046036 ! CTP metabolic process + +[Term] +id: GO:0006255 +name: obsolete UDP reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "UDP reduction" EXACT [] +is_obsolete: true +consider: GO:0051062 + +[Term] +id: GO:0006256 +name: UDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate." [ISBN:0198506732] +synonym: "UDP breakdown" EXACT [] +synonym: "UDP catabolism" EXACT [] +synonym: "UDP degradation" EXACT [] +is_a: GO:0009195 ! pyrimidine ribonucleoside diphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046048 ! UDP metabolic process + +[Term] +id: GO:0006257 +name: dUDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate." [ISBN:0198506732] +synonym: "dUDP breakdown" EXACT [] +synonym: "dUDP catabolism" EXACT [] +synonym: "dUDP degradation" EXACT [] +is_a: GO:0009198 ! pyrimidine deoxyribonucleoside diphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046077 ! dUDP metabolic process + +[Term] +id: GO:0006258 +name: UDP-glucose catabolic process +namespace: biological_process +alt_id: GO:0019691 +def: "The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-glucose breakdown" EXACT [] +synonym: "UDP-glucose catabolism" EXACT [] +synonym: "UDP-glucose conversion" RELATED [] +synonym: "UDP-glucose degradation" EXACT [] +is_a: GO:0006011 ! UDP-glucose metabolic process +is_a: GO:0009227 ! nucleotide-sugar catabolic process + +[Term] +id: GO:0006259 +name: DNA metabolic process +namespace: biological_process +alt_id: GO:0055132 +def: "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." [ISBN:0198506732] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "cellular DNA metabolism" EXACT [] +synonym: "DNA metabolism" EXACT [] +is_a: GO:0044260 ! cellular macromolecule metabolic process +is_a: GO:0090304 ! nucleic acid metabolic process + +[Term] +id: GO:0006260 +name: DNA replication +namespace: biological_process +alt_id: GO:0055133 +def: "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." [GOC:mah] +comment: DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'. +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +xref: Wikipedia:DNA_replication +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +relationship: has_part GO:0071897 ! DNA biosynthetic process + +[Term] +id: GO:0006261 +name: DNA-dependent DNA replication +namespace: biological_process +alt_id: GO:0006262 +alt_id: GO:0006263 +def: "A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." [GOC:mah, ISBN:0198506732] +is_a: GO:0006260 ! DNA replication + +[Term] +id: GO:0006264 +name: mitochondrial DNA replication +namespace: biological_process +def: "The process in which new strands of DNA are synthesized in the mitochondrion." [GOC:ai] +synonym: "mitochondrial DNA synthesis" RELATED [] +synonym: "mtDNA replication" EXACT [] +synonym: "mtDNA synthesis" RELATED [] +synonym: "replication of mitochondrial DNA" EXACT [] +is_a: GO:0006261 ! DNA-dependent DNA replication +intersection_of: GO:0006260 ! DNA replication +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0006265 +name: DNA topological change +namespace: biological_process +def: "The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number." [ISBN:071673706X, ISBN:0935702490] +comment: Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo. +synonym: "DNA underwinding" NARROW [] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0071103 ! DNA conformation change + +[Term] +id: GO:0006266 +name: DNA ligation +namespace: biological_process +def: "The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [ISBN:0815316194] +subset: goslim_pir +is_a: GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0006267 +name: pre-replicative complex assembly involved in nuclear cell cycle DNA replication +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation." [GOC:mtg_cell_cycle] +synonym: "nuclear pre-replicative complex assembly" EXACT [] +synonym: "pre-RC complex assembly" BROAD [] +synonym: "pre-replicative complex assembly" BROAD [GOC:bf, GOC:bhm, GOC:jh2] +synonym: "pre-replicative complex formation" BROAD [] +is_a: GO:1902299 ! pre-replicative complex assembly involved in cell cycle DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication + +[Term] +id: GO:0006268 +name: DNA unwinding involved in DNA replication +namespace: biological_process +def: "The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication." [ISBN:071673706X, ISBN:0815316194] +comment: Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'. +synonym: "DNA unwinding during replication" RELATED [GOC:dph, GOC:tb] +synonym: "DNA unwinding factor" RELATED [] +is_a: GO:0032508 ! DNA duplex unwinding +intersection_of: GO:0032508 ! DNA duplex unwinding +intersection_of: part_of GO:0006261 ! DNA-dependent DNA replication +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0006269 +name: DNA replication, synthesis of RNA primer +namespace: biological_process +def: "The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis." [PMID:11395402] +synonym: "replication priming" RELATED [] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0006270 +name: DNA replication initiation +namespace: biological_process +alt_id: GO:0042024 +def: "The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate." [ISBN:071673706X, ISBN:0815316194, PMID:28209641] +synonym: "DNA endoreduplication initiation" NARROW [] +synonym: "DNA re-replication initiation" NARROW [] +synonym: "DNA-dependent DNA replication initiation" EXACT [GOC:vw] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0006271 +name: DNA strand elongation involved in DNA replication +namespace: biological_process +def: "The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication." [GOC:mah, ISBN:071673706X, ISBN:0815316194] +synonym: "DNA replication elongation" EXACT [] +synonym: "DNA strand elongation during DNA replication" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022616 ! DNA strand elongation +intersection_of: GO:0022616 ! DNA strand elongation +intersection_of: part_of GO:0006260 ! DNA replication +relationship: has_part GO:0090592 ! DNA synthesis involved in DNA replication +relationship: part_of GO:0006261 ! DNA-dependent DNA replication +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12633 xsd:anyURI + +[Term] +id: GO:0006272 +name: leading strand elongation +namespace: biological_process +def: "The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork." [GOC:mah, ISBN:071673706X, ISBN:0815316194] +is_a: GO:0006271 ! DNA strand elongation involved in DNA replication +relationship: has_part GO:0006269 ! DNA replication, synthesis of RNA primer +relationship: has_part GO:0043137 ! DNA replication, removal of RNA primer +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12633 xsd:anyURI + +[Term] +id: GO:0006273 +name: lagging strand elongation +namespace: biological_process +def: "The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork." [GOC:mah, ISBN:071673706X, ISBN:0815316194] +is_a: GO:0006271 ! DNA strand elongation involved in DNA replication +relationship: has_part GO:0006269 ! DNA replication, synthesis of RNA primer +relationship: has_part GO:0043137 ! DNA replication, removal of RNA primer +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12633 xsd:anyURI + +[Term] +id: GO:0006274 +name: DNA replication termination +namespace: biological_process +def: "The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet." [GOC:mah, PMID:10209736, PMID:12009298] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0006275 +name: regulation of DNA replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA replication." [GOC:go_curators] +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006260 ! DNA replication +relationship: regulates GO:0006260 ! DNA replication + +[Term] +id: GO:0006276 +name: plasmid maintenance +namespace: biological_process +def: "The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division." [GOC:ai] +subset: goslim_pir +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0006277 +name: DNA amplification +namespace: biological_process +def: "The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment." [ISBN:0721601464] +is_a: GO:0071897 ! DNA biosynthetic process + +[Term] +id: GO:0006278 +name: RNA-dependent DNA biosynthetic process +namespace: biological_process +def: "A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand." [GOC:mah, ISBN:0198506732] +is_a: GO:0071897 ! DNA biosynthetic process + +[Term] +id: GO:0006279 +name: premeiotic DNA replication +namespace: biological_process +alt_id: GO:1902968 +def: "The replication of DNA that precedes meiotic cell division." [GO_REF:0000060, GOC:ai, GOC:TermGenie] +synonym: "DNA replication during S phase involved in meiotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA replication involved in S phase involved in meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication involved in S-phase involved in meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "meiotic cell cycle DNA replication" EXACT [] +synonym: "meiotic DNA replication" RELATED [GOC:mah] +synonym: "meiotic DNA synthesis" RELATED [GOC:mah] +synonym: "meiotic nuclear cell cycle DNA replication" EXACT [] +synonym: "nuclear cell cycle DNA replication involved in meiotic cell cycle" EXACT [] +synonym: "premeiotic DNA synthesis" RELATED [GOC:mah] +is_a: GO:0033260 ! nuclear DNA replication +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0033260 ! nuclear DNA replication +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0006280 +name: obsolete mutagenesis +namespace: biological_process +def: "OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level." [ISBN:0198506732] +comment: This term was made obsolete because mutagenesis is not a valid biological process in which gene products would normally participate. Rather, mutations arise from DNA replication errors or damage by an extrinsic agent. +synonym: "mutagenesis" EXACT [] +is_obsolete: true +consider: GO:0006281 +consider: GO:0051276 + +[Term] +id: GO:0006281 +name: DNA repair +namespace: biological_process +def: "The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway." [PMID:11563486] +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +xref: Wikipedia:DNA_repair +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0006974 ! cellular response to DNA damage stimulus + +[Term] +id: GO:0006282 +name: regulation of DNA repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA repair." [GOC:go_curators] +subset: goslim_metagenomics +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006281 ! DNA repair +relationship: regulates GO:0006281 ! DNA repair + +[Term] +id: GO:0006283 +name: transcription-coupled nucleotide-excision repair +namespace: biological_process +def: "The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway." [PMID:10197977, PMID:11900249] +synonym: "TC-NER" EXACT [PMID:10197977] +synonym: "TCR" RELATED [GOC:vw, PMID:18794354] +synonym: "transcription-coupled NER" EXACT [GOC:mah] +synonym: "transcription-coupled repair" EXACT [GOC:vw, PMID:18794354] +is_a: GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0006284 +name: base-excision repair +namespace: biological_process +def: "In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase." [ISBN:0815316194] +synonym: "BER" EXACT [] +xref: Wikipedia:Base_excision_repair +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006285 +name: base-excision repair, AP site formation +namespace: biological_process +def: "The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired." [ISBN:0815316194] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006284 ! base-excision repair + +[Term] +id: GO:0006286 +name: base-excision repair, base-free sugar-phosphate removal +namespace: biological_process +def: "Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme." [ISBN:0815316194] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0098502 ! DNA dephosphorylation +relationship: part_of GO:0006284 ! base-excision repair + +[Term] +id: GO:0006287 +name: base-excision repair, gap-filling +namespace: biological_process +def: "Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template." [ISBN:1550091131] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006284 ! base-excision repair + +[Term] +id: GO:0006288 +name: base-excision repair, DNA ligation +namespace: biological_process +def: "The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair." [ISBN:1550091131] +is_a: GO:0051103 ! DNA ligation involved in DNA repair +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0006284 ! base-excision repair +relationship: part_of GO:0006284 ! base-excision repair + +[Term] +id: GO:0006289 +name: nucleotide-excision repair +namespace: biological_process +alt_id: GO:0045001 +def: "A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)." [PMID:10197977] +comment: Note that although intrastrand cross-link repair is not exactly synonymous with nucleotide excision repair, nucleotide excision repair includes the repair of intrastrand cross-links. The synonym field is being used to reflect the broad substrate specificity of nucleotide excision repair. +synonym: "intrastrand cross-link repair" RELATED [] +synonym: "NER" EXACT [] +synonym: "pyrimidine-dimer repair, DNA damage excision" EXACT [] +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006290 +name: pyrimidine dimer repair +namespace: biological_process +def: "The repair of UV-induced T-T, C-T and C-C dimers." [ISBN:0815316194] +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006291 +name: obsolete pyrimidine-dimer repair, DNA damage excision +namespace: biological_process +def: "OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme." [ISBN:0815316194] +comment: This term was made obsolete because this process can be subdivided into multiple processes. +synonym: "pyrimidine-dimer repair, DNA damage excision" EXACT [] +is_obsolete: true +consider: GO:0006289 + +[Term] +id: GO:0006292 +name: obsolete pyrimidine-dimer repair, DNA damage recognition +namespace: biological_process +def: "OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers." [ISBN:0815316194] +comment: This term was made obsolete because it is a substrate specific DNA repair process. +synonym: "pyrimidine-dimer repair, DNA damage recognition" EXACT [] +is_obsolete: true +consider: GO:0000715 +consider: GO:0000716 + +[Term] +id: GO:0006293 +name: nucleotide-excision repair, preincision complex stabilization +namespace: biological_process +def: "The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage." [GOC:elh, PMID:10197977] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0006294 +name: nucleotide-excision repair, preincision complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage." [GOC:elh, PMID:10197977] +synonym: "nucleotide-excision repair, preincision complex formation" EXACT [] +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0006295 +name: nucleotide-excision repair, DNA incision, 3'-to lesion +namespace: biological_process +def: "The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage." [GOC:elh, PMID:10197977] +synonym: "nucleotide-excision repair, DNA incision, 3' to lesion" EXACT [] +is_a: GO:0033683 ! nucleotide-excision repair, DNA incision + +[Term] +id: GO:0006296 +name: nucleotide-excision repair, DNA incision, 5'-to lesion +namespace: biological_process +def: "The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage." [GOC:elh, PMID:10197977] +synonym: "nucleotide-excision repair, DNA incision, 5' to lesion" EXACT [] +is_a: GO:0033683 ! nucleotide-excision repair, DNA incision + +[Term] +id: GO:0006297 +name: nucleotide-excision repair, DNA gap filling +namespace: biological_process +def: "Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes." [ISBN:0815316194] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0006298 +name: mismatch repair +namespace: biological_process +alt_id: GO:0006300 +def: "A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination." [ISBN:0198506732, PMID:11687886] +synonym: "long patch mismatch repair system" NARROW [] +synonym: "mismatch repair, MutL-like pathway" RELATED [] +synonym: "MMR" EXACT [] +synonym: "MutS/MutL/MutH pathway" RELATED [] +xref: Wikipedia:DNA_mismatch_repair +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006299 +name: obsolete short patch mismatch repair system +namespace: biological_process +def: "OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site." [PMID:10660619, PMID:10878254] +comment: This term was made obsolete because 'short patch' is a relative statement, often used ambiguously, and does not necessarily represent a process; the processes it can stand for are base excision repair, nucleotide excision repair, transcription-coupled nucleotide excision repair, and mismatch repair. +synonym: "short patch mismatch repair system" EXACT [] +is_obsolete: true +consider: GO:0006284 +consider: GO:0006289 + +[Term] +id: GO:0006301 +name: postreplication repair +namespace: biological_process +def: "The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication." [GOC:elh] +synonym: "postreplication DNA repair" EXACT [] +xref: Wikipedia:Postreplication_repair +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006302 +name: double-strand break repair +namespace: biological_process +def: "The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix." [GOC:elh] +comment: Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable (PMID:22214610). To annotate gene products involved in mitochondrial double-strand break repair, please use GO:0097551 'mitochondrial double-strand break repair'. +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0006303 +name: double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear." [GOC:rph, PMID:10827453, PMID:24837021] +synonym: "NHEJ" EXACT [] +is_a: GO:0000726 ! non-recombinational repair +is_a: GO:0006302 ! double-strand break repair + +[Term] +id: GO:0006304 +name: DNA modification +namespace: biological_process +def: "The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties." [GOC:jl, GOC:ma] +subset: goslim_pir +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0043412 ! macromolecule modification + +[Term] +id: GO:0006305 +name: DNA alkylation +namespace: biological_process +def: "The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis." [ISBN:0716735970] +is_a: GO:0006304 ! DNA modification + +[Term] +id: GO:0006306 +name: DNA methylation +namespace: biological_process +def: "The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine." [GOC:ems, ISBN:0198506732] +xref: Wikipedia:DNA_methylation +is_a: GO:0006305 ! DNA alkylation +is_a: GO:0043414 ! macromolecule methylation +is_a: GO:0044728 ! DNA methylation or demethylation +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4930 + +[Term] +id: GO:0006307 +name: DNA dealkylation involved in DNA repair +namespace: biological_process +def: "The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT)." [PMID:10946226] +is_a: GO:0035510 ! DNA dealkylation +intersection_of: GO:0035510 ! DNA dealkylation +intersection_of: part_of GO:0006281 ! DNA repair +relationship: part_of GO:0006281 ! DNA repair + +[Term] +id: GO:0006308 +name: DNA catabolic process +namespace: biological_process +def: "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:go_curators, ISBN:0198506732] +subset: goslim_drosophila +synonym: "DNA breakdown" EXACT [] +synonym: "DNA catabolism" EXACT [] +synonym: "DNA degradation" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0034655 ! nucleobase-containing compound catabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process +relationship: has_part GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0006309 +name: apoptotic DNA fragmentation +namespace: biological_process +alt_id: GO:0008178 +def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520] +comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). +synonym: "chromatinolysis" BROAD [GOC:mtg_apoptosis] +synonym: "DNA catabolic process during apoptosis" EXACT [] +synonym: "DNA catabolism during apoptosis" EXACT [] +synonym: "DNA fragmentation" BROAD [] +synonym: "DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:cjm, GOC:dph, GOC:tb] +synonym: "endonucleolytic DNA catabolic process involved in apoptosis" EXACT [] +is_a: GO:0000737 ! DNA catabolic process, endonucleolytic +intersection_of: GO:0000737 ! DNA catabolic process, endonucleolytic +intersection_of: part_of GO:0030262 ! apoptotic nuclear changes +relationship: part_of GO:0030262 ! apoptotic nuclear changes + +[Term] +id: GO:0006310 +name: DNA recombination +namespace: biological_process +def: "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pombe +subset: goslim_yeast +is_a: GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0006311 +name: meiotic gene conversion +namespace: biological_process +def: "The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele." [ISBN:0815316194] +synonym: "gene conversion without reciprocal crossover" EXACT [] +is_a: GO:0035822 ! gene conversion +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0006312 +name: mitotic recombination +namespace: biological_process +def: "The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles." [GOC:elh] +xref: Wikipedia:Mitotic_crossover +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0006313 +name: transposition, DNA-mediated +namespace: biological_process +alt_id: GO:0006317 +alt_id: GO:0006318 +def: "Any process involved in a type of transpositional recombination which occurs via a DNA intermediate." [GOC:jp, ISBN:0198506732, ISBN:1555812090] +synonym: "Class II transposition" EXACT [] +synonym: "DNA transposition" EXACT [GOC:dph] +synonym: "P-element excision" NARROW [] +synonym: "P-element transposition" NARROW [] +synonym: "Tc1/mariner transposition" NARROW [] +synonym: "Tc3 transposition" NARROW [] +is_a: GO:0006310 ! DNA recombination +is_a: GO:0032196 ! transposition + +[Term] +id: GO:0006314 +name: intron homing +namespace: biological_process +def: "Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron." [PMID:10487208] +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0006315 +name: homing of group II introns +namespace: biological_process +def: "Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure." [GOC:mcc, ISBN:0716743663, PMID:10487208] +is_a: GO:0006314 ! intron homing + +[Term] +id: GO:0006316 +name: movement of group I intron +namespace: biological_process +def: "Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction." [GOC:mcc, ISBN:0716743663, PMID:10487208] +is_a: GO:0006314 ! intron homing + +[Term] +id: GO:0006323 +name: DNA packaging +namespace: biological_process +def: "Any process in which DNA and associated proteins are formed into a compact, orderly structure." [GOC:mah, ISBN:0815316194] +subset: goslim_pir +synonym: "DNA condensation" EXACT [] +synonym: "DNA organisation" EXACT [] +synonym: "DNA organization" EXACT [] +is_a: GO:0071103 ! DNA conformation change +relationship: has_part GO:0008301 ! DNA binding, bending + +[Term] +id: GO:0006324 +name: obsolete S phase-specific histone modification +namespace: biological_process +def: "OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle." [GOC:mah, PMID:9990026] +comment: This term was made obsolete because histone modification already exists and the phase specificity is better captured as an annotation extension. +synonym: "S phase-specific histone modification" EXACT [] +synonym: "S-phase-specific histone modification" EXACT [] +is_obsolete: true +consider: GO:0016570 + +[Term] +id: GO:0006325 +name: chromatin organization +namespace: biological_process +alt_id: GO:0016568 +def: "Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GOC:mah, GOC:vw, PMID:20404130] +subset: goslim_pombe +subset: goslim_yeast +synonym: "chromatin modification" RELATED [] +synonym: "chromatin organisation" EXACT [GOC:mah] +synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0051276 ! chromosome organization + +[Term] +id: GO:0006326 +name: obsolete bent DNA binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "bent DNA binding" EXACT [] +is_obsolete: true +replaced_by: GO:0003681 + +[Term] +id: GO:0006327 +name: obsolete random coil binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "random coil binding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006328 +name: obsolete AT binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "AT binding" EXACT [] +is_obsolete: true +replaced_by: GO:0003680 + +[Term] +id: GO:0006329 +name: obsolete satellite DNA binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "satellite DNA binding" EXACT [] +is_obsolete: true +replaced_by: GO:0003696 + +[Term] +id: GO:0006330 +name: obsolete single-stranded DNA binding +namespace: biological_process +alt_id: GO:0006331 +alt_id: GO:0006332 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "single-stranded DNA binding" EXACT [] +is_obsolete: true +replaced_by: GO:0003697 + +[Term] +id: GO:0006333 +name: chromatin assembly or disassembly +namespace: biological_process +def: "The formation or destruction of chromatin structures." [GOC:mah] +synonym: "chromatin assembly/disassembly" EXACT [] +is_a: GO:0006325 ! chromatin organization + +[Term] +id: GO:0006334 +name: nucleosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA." [GOC:mah] +synonym: "histone chaperone" RELATED [GOC:vw] +synonym: "nucleosome modeling" EXACT [] +is_a: GO:0034728 ! nucleosome organization +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0031497 ! chromatin assembly + +[Term] +id: GO:0006335 +name: DNA replication-dependent nucleosome assembly +namespace: biological_process +def: "The formation of nucleosomes on newly replicated DNA, coupled to strand elongation." [GOC:mah] +is_a: GO:0006334 ! nucleosome assembly +is_a: GO:0034723 ! DNA replication-dependent nucleosome organization + +[Term] +id: GO:0006336 +name: DNA replication-independent nucleosome assembly +namespace: biological_process +def: "The formation of nucleosomes outside the context of DNA replication." [GOC:mah] +synonym: "transcription-coupled nucleosome assembly" EXACT [] +is_a: GO:0006334 ! nucleosome assembly +is_a: GO:0034724 ! DNA replication-independent nucleosome organization + +[Term] +id: GO:0006337 +name: nucleosome disassembly +namespace: biological_process +def: "The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA." [GOC:mah] +is_a: GO:0032986 ! protein-DNA complex disassembly +is_a: GO:0034728 ! nucleosome organization +relationship: part_of GO:0031498 ! chromatin disassembly + +[Term] +id: GO:0006338 +name: chromatin remodeling +namespace: biological_process +def: "Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation." [GOC:jid, GOC:vw, PMID:12697820] +synonym: "chromatin modeling" EXACT [] +synonym: "chromatin modelling" EXACT [] +synonym: "chromatin remodelling" EXACT [] +is_a: GO:0006325 ! chromatin organization + +[Term] +id: GO:0006339 +name: obsolete positive regulation of transcription of homeotic gene (trithorax group) +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "positive regulation of transcription of homeotic gene (trithorax group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0006340 +name: obsolete negative regulation of transcription of homeotic gene (Polycomb group) +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "negative regulation of transcription of homeotic gene (Polycomb group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0006341 +name: obsolete chromatin insulator sequence binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "chromatin insulator sequence binding" EXACT [] +is_obsolete: true +replaced_by: GO:0043035 + +[Term] +id: GO:0006342 +name: chromatin silencing +namespace: biological_process +alt_id: GO:0016440 +def: "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245] +comment: Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription. +synonym: "chromatin-mediated maintenance of transcriptional inactivation" EXACT [] +synonym: "chromatin-mediated silencing" EXACT [] +synonym: "heterochromatic silencing" RELATED [] +synonym: "TGS" EXACT [] +synonym: "transcriptional gene silencing" EXACT [] +is_a: GO:0016458 ! gene silencing +is_a: GO:0045814 ! negative regulation of gene expression, epigenetic +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:0097549 ! chromatin organization involved in negative regulation of transcription + +[Term] +id: GO:0006346 +name: DNA methylation-dependent heterochromatin assembly +namespace: biological_process +def: "Repression of transcription by methylation of DNA, leading to the formation of heterochromatin." [GOC:mah] +synonym: "methylation-dependent chromatin silencing" BROAD [] +synonym: "methylation-dependent heterochromatic silencing" BROAD [] +is_a: GO:0016569 ! covalent chromatin modification +is_a: GO:0031507 ! heterochromatin assembly +relationship: has_part GO:0006306 ! DNA methylation + +[Term] +id: GO:0006348 +name: chromatin silencing at telomere +namespace: biological_process +def: "Repression of transcription of telomeric DNA by altering the structure of chromatin." [PMID:10219245] +synonym: "heterochromatic silencing at telomere" EXACT [] +synonym: "telomere chromatin silencing" EXACT [GOC:mah] +synonym: "Telomere Position Effect" EXACT [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:21847107] +synonym: "telomeric silencing" EXACT [GOC:bf] +is_a: GO:0006342 ! chromatin silencing +intersection_of: GO:0006342 ! chromatin silencing +intersection_of: occurs_in GO:0000781 ! chromosome, telomeric region +relationship: occurs_in GO:0000781 ! chromosome, telomeric region + +[Term] +id: GO:0006349 +name: regulation of gene expression by genetic imprinting +namespace: biological_process +def: "Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself." [GOC:ems, ISBN:0198506732, PMID:11498578] +synonym: "regulation of gene expression by DNA imprinting" EXACT [GOC:mah] +xref: Wikipedia:Genomic_imprinting +is_a: GO:0040029 ! regulation of gene expression, epigenetic +is_a: GO:0071514 ! genetic imprinting +intersection_of: GO:0071514 ! genetic imprinting +intersection_of: regulates GO:0010467 ! gene expression + +[Term] +id: GO:0006351 +name: transcription, DNA-templated +namespace: biological_process +alt_id: GO:0006350 +alt_id: GO:0061018 +alt_id: GO:0061022 +def: "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] +subset: goslim_aspergillus +subset: goslim_drosophila +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_pombe +synonym: "cellular transcription" BROAD [] +synonym: "cellular transcription, DNA-dependent" EXACT [] +synonym: "DNA-dependent transcription" EXACT [] +synonym: "transcription" BROAD [] +synonym: "transcription regulator activity" RELATED [] +synonym: "transcription, DNA-dependent" EXACT [GOC:txnOH] +xref: Wikipedia:Transcription_(genetics) +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0097659 ! nucleic acid-templated transcription +relationship: part_of GO:0010467 ! gene expression + +[Term] +id: GO:0006352 +name: DNA-templated transcription, initiation +namespace: biological_process +def: "Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription." [GOC:jid, GOC:txnOH, PMID:18280161] +comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation. +subset: goslim_yeast +synonym: "DNA-dependent RNA polymerase complex assembly at promoter" EXACT [] +synonym: "DNA-dependent transcription, initiation" EXACT [GOC:txnOH] +synonym: "initiation of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "initiation of transcription, DNA-dependent" EXACT [GOC:mah] +synonym: "transcription initiation factor activity" RELATED [] +synonym: "transcription initiation, DNA-dependent" RELATED [GOC:jh2] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0006353 +name: DNA-templated transcription, termination +namespace: biological_process +def: "The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:txnOH, ISBN:0716720094, PMID:15020047, PMID:18280161] +subset: goslim_yeast +synonym: "DNA-dependent transcription, termination" EXACT [GOC:txnOH] +synonym: "termination of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "termination of transcription, DNA-dependent" EXACT [GOC:mah] +synonym: "transcription termination factor activity" RELATED [] +synonym: "transcription termination, DNA-dependent" RELATED [GOC:jh2] +synonym: "transcriptional complex disassembly" BROAD [] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0006354 +name: DNA-templated transcription, elongation +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase." [GOC:mah, GOC:txnOH, PMID:15020047, PMID:18280161] +subset: goslim_pir +subset: goslim_yeast +synonym: "DNA-dependent transcription, elongation" EXACT [GOC:txnOH] +synonym: "RNA elongation" BROAD [] +synonym: "transcription elongation, DNA-dependent" EXACT [GOC:jh2] +synonym: "transcriptional elongation, DNA-dependent" EXACT [] +is_a: GO:0032774 ! RNA biosynthetic process +relationship: part_of GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0006355 +name: regulation of transcription, DNA-templated +namespace: biological_process +alt_id: GO:0032583 +alt_id: GO:0045449 +alt_id: GO:0061019 +def: "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "regulation of cellular transcription, DNA-dependent" EXACT [] +synonym: "regulation of gene-specific transcription" RELATED [] +synonym: "regulation of transcription, DNA-dependent" EXACT [GOC:txnOH] +synonym: "transcriptional control" BROAD [] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:1903506 ! regulation of nucleic acid-templated transcription +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006351 ! transcription, DNA-templated +relationship: regulates GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0006356 +name: regulation of transcription by RNA polymerase I +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I." [GOC:go_curators] +synonym: "regulation of transcription from Pol I promoter" EXACT [] +synonym: "regulation of transcription from RNA polymerase I promoter" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006360 ! transcription by RNA polymerase I +relationship: regulates GO:0006360 ! transcription by RNA polymerase I + +[Term] +id: GO:0006357 +name: regulation of transcription by RNA polymerase II +namespace: biological_process +alt_id: GO:0006358 +alt_id: GO:0010551 +def: "Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II." [GOC:go_curators, GOC:txnOH] +synonym: "global transcription regulation from Pol II promoter" RELATED [] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [] +synonym: "regulation of global transcription from Pol II promoter" RELATED [] +synonym: "regulation of transcription from Pol II promoter" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter, global" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006366 ! transcription by RNA polymerase II +relationship: regulates GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0006359 +name: regulation of transcription by RNA polymerase III +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III." [GOC:go_curators] +synonym: "regulation of transcription from Pol III promoter" EXACT [] +synonym: "regulation of transcription from RNA polymerase III promoter" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006383 ! transcription by RNA polymerase III +relationship: regulates GO:0006383 ! transcription by RNA polymerase III + +[Term] +id: GO:0006360 +name: transcription by RNA polymerase I +namespace: biological_process +def: "The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter." [GOC:jl, GOC:txnOH] +subset: goslim_yeast +synonym: "RNA polymerase I transcription factor activity" RELATED [] +synonym: "transcription from Pol I promoter" EXACT [] +synonym: "transcription from RNA polymerase I promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0006361 +name: transcription initiation from RNA polymerase I promoter +namespace: biological_process +alt_id: GO:0001180 +def: "Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription." [GOC:mah, GOC:txnOH] +comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation. +synonym: "transcription initiation from Pol I promoter" EXACT [] +synonym: "transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript" NARROW [] +is_a: GO:0006352 ! DNA-templated transcription, initiation +relationship: part_of GO:0006360 ! transcription by RNA polymerase I +created_by: krc +creation_date: 2011-08-15T03:45:49Z + +[Term] +id: GO:0006362 +name: transcription elongation from RNA polymerase I promoter +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I." [GOC:mah, GOC:txnOH] +synonym: "RNA elongation from Pol I promoter" EXACT [] +synonym: "RNA polymerase I transcription elongation factor activity" RELATED [] +is_a: GO:0006354 ! DNA-templated transcription, elongation +relationship: part_of GO:0006360 ! transcription by RNA polymerase I + +[Term] +id: GO:0006363 +name: termination of RNA polymerase I transcription +namespace: biological_process +alt_id: GO:0001185 +alt_id: GO:0019223 +def: "The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit." [GOC:mah, GOC:txnOH, PMID:10684922] +synonym: "RNA polymerase I transcription termination" EXACT [] +synonym: "RNA polymerase I transcription termination factor activity" RELATED [] +synonym: "termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript" NARROW [] +synonym: "transcription termination from Pol I promoter" EXACT [] +synonym: "transcription termination from RNA polymerase I promoter" EXACT [] +is_a: GO:0006353 ! DNA-templated transcription, termination +relationship: part_of GO:0006360 ! transcription by RNA polymerase I +created_by: krc +creation_date: 2011-08-15T04:07:43Z + +[Term] +id: GO:0006364 +name: rRNA processing +namespace: biological_process +alt_id: GO:0006365 +def: "Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules." [GOC:curators] +subset: goslim_yeast +synonym: "35S primary transcript processing" NARROW [] +is_a: GO:0016072 ! rRNA metabolic process +is_a: GO:0034470 ! ncRNA processing +relationship: part_of GO:0042254 ! ribosome biogenesis + +[Term] +id: GO:0006366 +name: transcription by RNA polymerase II +namespace: biological_process +alt_id: GO:0032568 +alt_id: GO:0032569 +def: "The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)." [GOC:jl, GOC:txnOH, ISBN:0321000382] +subset: goslim_yeast +synonym: "gene-specific transcription from RNA polymerase II promoter" RELATED [] +synonym: "general transcription from RNA polymerase II promoter" RELATED [] +synonym: "RNA polymerase II transcription factor activity" RELATED [] +synonym: "specific transcription from RNA polymerase II promoter" RELATED [GOC:mah] +synonym: "transcription from Pol II promoter" EXACT [] +synonym: "transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0006367 +name: transcription initiation from RNA polymerase II promoter +namespace: biological_process +def: "Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription." [GOC:mah, GOC:txnOH] +comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation. +synonym: "transcription initiation from Pol II promoter" EXACT [] +is_a: GO:0006352 ! DNA-templated transcription, initiation +relationship: part_of GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0006368 +name: transcription elongation from RNA polymerase II promoter +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II." [GOC:mah, GOC:txnOH] +synonym: "RNA elongation from Pol II promoter" EXACT [] +synonym: "RNA polymerase II transcription elongation factor activity" RELATED [] +is_a: GO:0006354 ! DNA-templated transcription, elongation +relationship: part_of GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0006369 +name: termination of RNA polymerase II transcription +namespace: biological_process +alt_id: GO:0019224 +def: "The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed." [GOC:mah, GOC:txnOH] +synonym: "RNA 3'-end formation by RNA polymerase II" EXACT [] +synonym: "RNA polymerase II transcription termination" EXACT [] +synonym: "RNA polymerase II transcription termination factor activity" RELATED [] +synonym: "transcription termination from Pol II promoter" EXACT [] +synonym: "transcription termination from RNA polymerase II promoter" EXACT [] +is_a: GO:0006353 ! DNA-templated transcription, termination +relationship: part_of GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0006370 +name: 7-methylguanosine mRNA capping +namespace: biological_process +def: "Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript." [GOC:mah, PMID:9266685] +synonym: "5' end capping" BROAD [] +synonym: "5' mRNA capping" EXACT [] +synonym: "5'-end mRNA processing" EXACT [] +synonym: "5'-end processing" BROAD [] +synonym: "mRNA capping" EXACT [GOC:bf, GOC:krc, GOC:mah] +is_a: GO:0006397 ! mRNA processing +is_a: GO:0009452 ! 7-methylguanosine RNA capping + +[Term] +id: GO:0006371 +name: obsolete mRNA splicing +namespace: biological_process +def: "OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732] +comment: This term was made obsolete because it represents several different processes. +synonym: "mRNA splicing" EXACT [] +is_obsolete: true +consider: GO:0000372 +consider: GO:0000373 +consider: GO:0000374 +consider: GO:0000394 +consider: GO:0000398 + +[Term] +id: GO:0006372 +name: obsolete lariat formation, 5'-splice site cleavage +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it represents a molecular function. +synonym: "lariat formation, 5'-splice site cleavage" EXACT [] +is_obsolete: true +consider: GO:0000350 +consider: GO:0000386 + +[Term] +id: GO:0006373 +name: obsolete 3'-splice site cleavage, exon ligation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it represents a molecular function. +synonym: "3'-splice site cleavage, exon ligation" EXACT [] +is_obsolete: true +consider: GO:0000386 +consider: GO:0000388 +consider: GO:0000393 + +[Term] +id: GO:0006376 +name: mRNA splice site selection +namespace: biological_process +def: "Selection of a splice site by components of the assembling spliceosome." [GOC:krc, ISBN:0879695897] +synonym: "spliceosomal commitment complex biosynthesis" NARROW [] +synonym: "spliceosomal commitment complex formation" NARROW [] +synonym: "spliceosomal E complex biosynthesis" NARROW [] +synonym: "spliceosomal E complex formation" NARROW [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000245 ! spliceosomal complex assembly + +[Term] +id: GO:0006377 +name: obsolete MATa1 (A1) pre-mRNA splicing +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it does not represent a process unique to splicing of the MATa1 (A1) pre-mRNA, but a recycling defect exacerbated by the presence of two introns within the same gene. +synonym: "MATa1 (A1) pre-mRNA splicing" EXACT [] +is_obsolete: true +consider: GO:0000244 + +[Term] +id: GO:0006378 +name: mRNA polyadenylation +namespace: biological_process +def: "The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript." [ISBN:0198506732] +synonym: "cleavage and polyadenylylation specificity factor activity" NARROW [] +synonym: "mRNA polyadenylylation" EXACT [] +is_a: GO:0031124 ! mRNA 3'-end processing +is_a: GO:0043631 ! RNA polyadenylation + +[Term] +id: GO:0006379 +name: mRNA cleavage +namespace: biological_process +def: "Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner." [GOC:mah] +synonym: "cleavage stimulation factor activity" RELATED [] +is_a: GO:0016071 ! mRNA metabolic process +is_a: GO:0090501 ! RNA phosphodiester bond hydrolysis + +[Term] +id: GO:0006380 +name: obsolete poly-A binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "poly-A binding" EXACT [] +is_obsolete: true +consider: GO:0008143 + +[Term] +id: GO:0006382 +name: adenosine to inosine editing +namespace: biological_process +def: "The conversion of an adenosine residue to inosine in an RNA molecule by deamination." [PMID:11092837] +is_a: GO:0016553 ! base conversion or substitution editing + +[Term] +id: GO:0006383 +name: transcription by RNA polymerase III +namespace: biological_process +alt_id: GO:0001009 +alt_id: GO:0001035 +alt_id: GO:0001041 +def: "The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter." [GOC:jl, GOC:txnOH, PMID:12381659] +subset: goslim_yeast +synonym: "RNA polymerase III transcription factor activity" RELATED [] +synonym: "transcription from a RNA polymerase III hybrid type promoter" NARROW [] +synonym: "transcription from Pol III promoter" EXACT [] +synonym: "transcription from RNA polymerase III promoter" EXACT [] +synonym: "transcription from RNA polymerase III type 2 promoter" NARROW [] +synonym: "transcription from RNA polymerase III type 3 promoter" NARROW [] +synonym: "U2 snRNA transcription (S. cerevisiae)" NARROW [] +synonym: "U6 snRNA transcription (mammalian)" NARROW [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/9617 xsd:anyURI +created_by: krc +creation_date: 2010-08-18T06:37:56Z + +[Term] +id: GO:0006384 +name: transcription initiation from RNA polymerase III promoter +namespace: biological_process +alt_id: GO:0001022 +alt_id: GO:0001023 +alt_id: GO:0001024 +alt_id: GO:0001036 +def: "Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription." [GOC:mah, GOC:txnOH] +comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation. +synonym: "transcription initiation from Pol III promoter" EXACT [] +synonym: "transcription initiation from RNA polymerase III hybrid type promoter" NARROW [] +synonym: "transcription initiation from RNA polymerase III type 1 promoter" NARROW [] +synonym: "transcription initiation from RNA polymerase III type 2 promoter" NARROW [] +synonym: "transcription initiation from RNA polymerase III type 3 promoter" NARROW [] +is_a: GO:0006352 ! DNA-templated transcription, initiation +relationship: part_of GO:0006383 ! transcription by RNA polymerase III +created_by: krc +creation_date: 2010-08-19T04:33:52Z + +[Term] +id: GO:0006385 +name: transcription elongation from RNA polymerase III promoter +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III." [GOC:mah, GOC:txnOH] +synonym: "RNA elongation from Pol III promoter" EXACT [] +synonym: "RNA polymerase III transcription elongation factor activity" RELATED [] +is_a: GO:0006354 ! DNA-templated transcription, elongation +relationship: part_of GO:0006383 ! transcription by RNA polymerase III + +[Term] +id: GO:0006386 +name: termination of RNA polymerase III transcription +namespace: biological_process +alt_id: GO:0019225 +def: "The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues." [GOC:mah, PMID:12944462] +synonym: "RNA polymerase III transcription termination" EXACT [] +synonym: "RNA polymerase III transcription termination factor activity" RELATED [] +synonym: "transcription termination from Pol III promoter" EXACT [] +synonym: "transcription termination from RNA polymerase III promoter" EXACT [] +is_a: GO:0006353 ! DNA-templated transcription, termination +relationship: part_of GO:0006383 ! transcription by RNA polymerase III + +[Term] +id: GO:0006387 +name: obsolete snRNA capping +namespace: biological_process +def: "OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript." [GOC:mah] +comment: This term was made obsolete because it has been replaced with a more specific term to describe cap hypermethylation. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the 7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap. +synonym: "snRNA capping" EXACT [] +is_obsolete: true +consider: GO:0036261 + +[Term] +id: GO:0006388 +name: tRNA splicing, via endonucleolytic cleavage and ligation +namespace: biological_process +def: "Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons." [GOC:krc, ISBN:0879695897, PMID:9582290] +comment: Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis. +synonym: "tRNA-Y splicing" NARROW [] +is_a: GO:0000394 ! RNA splicing, via endonucleolytic cleavage and ligation +is_a: GO:0008033 ! tRNA processing + +[Term] +id: GO:0006389 +name: obsolete tRNA-Y splicing +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it does not represent a process unique to splicing of the tyrosyl (Y) tRNA. +synonym: "tRNA-Y splicing" EXACT [] +is_obsolete: true +consider: GO:0006388 + +[Term] +id: GO:0006390 +name: mitochondrial transcription +namespace: biological_process +def: "The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase." [GOC:jl] +synonym: "transcription from mitochondrial promoter" EXACT [] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006351 ! transcription, DNA-templated +intersection_of: GO:0006351 ! transcription, DNA-templated +intersection_of: occurs_in GO:0005739 ! mitochondrion +intersection_of: part_of GO:0140053 ! mitochondrial gene expression +relationship: part_of GO:0140053 ! mitochondrial gene expression +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0006391 +name: transcription initiation from mitochondrial promoter +namespace: biological_process +def: "A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase." [GOC:mah] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006352 ! DNA-templated transcription, initiation +relationship: part_of GO:0006390 ! mitochondrial transcription + +[Term] +id: GO:0006392 +name: transcription elongation from mitochondrial promoter +namespace: biological_process +def: "The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase." [GOC:mah, GOC:txnOH] +synonym: "RNA elongation from mitochondrial promoter" EXACT [] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006354 ! DNA-templated transcription, elongation +relationship: part_of GO:0006390 ! mitochondrial transcription + +[Term] +id: GO:0006393 +name: termination of mitochondrial transcription +namespace: biological_process +def: "The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed." [GOC:mah] +synonym: "mitochondrial transcription termination" EXACT [] +synonym: "RNA transcription termination from mitochondrial promoter" EXACT [] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006353 ! DNA-templated transcription, termination +intersection_of: GO:0006353 ! DNA-templated transcription, termination +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0006390 ! mitochondrial transcription + +[Term] +id: GO:0006396 +name: RNA processing +namespace: biological_process +alt_id: GO:0006394 +def: "Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." [GOC:mah] +subset: goslim_pir +xref: Wikipedia:Post-transcriptional_modification +is_a: GO:0016070 ! RNA metabolic process +relationship: part_of GO:0010467 ! gene expression + +[Term] +id: GO:0006397 +name: mRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "mRNA maturation" RELATED [] +is_a: GO:0006396 ! RNA processing +is_a: GO:0016071 ! mRNA metabolic process + +[Term] +id: GO:0006398 +name: mRNA 3'-end processing by stem-loop binding and cleavage +namespace: biological_process +def: "Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine." [GOC:mah, GOC:tb, PMID:17998288] +synonym: "histone mRNA 3' end processing" NARROW [] +is_a: GO:0008334 ! histone mRNA metabolic process +is_a: GO:0031124 ! mRNA 3'-end processing +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0006399 +name: tRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established." [ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pombe +synonym: "tRNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0006400 +name: tRNA modification +namespace: biological_process +alt_id: GO:0016549 +def: "The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically." [GOC:curators] +comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'. +synonym: "tRNA editing" NARROW [GOC:hjd] +is_a: GO:0008033 ! tRNA processing +is_a: GO:0009451 ! RNA modification + +[Term] +id: GO:0006401 +name: RNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_yeast +synonym: "RNA breakdown" EXACT [] +synonym: "RNA catabolism" EXACT [] +synonym: "RNA degradation" EXACT [] +is_a: GO:0016070 ! RNA metabolic process +is_a: GO:0034655 ! nucleobase-containing compound catabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process + +[Term] +id: GO:0006402 +name: mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." [ISBN:0198506732] +synonym: "mRNA breakdown" EXACT [] +synonym: "mRNA catabolism" EXACT [] +synonym: "mRNA decay" RELATED [GOC:ascb_2010, GOC:dph, GOC:tb] +synonym: "mRNA degradation" EXACT [] +is_a: GO:0006401 ! RNA catabolic process +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0016071 ! mRNA metabolic process + +[Term] +id: GO:0006403 +name: RNA localization +namespace: biological_process +def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai] +subset: goslim_drosophila +synonym: "establishment and maintenance of RNA localization" EXACT [] +synonym: "RNA localisation" EXACT [GOC:mah] +is_a: GO:0033036 ! macromolecule localization + +[Term] +id: GO:0006404 +name: RNA import into nucleus +namespace: biological_process +def: "The import of RNA from the cytoplasm to the nucleus." [GOC:ma] +synonym: "RNA import into cell nucleus" EXACT [] +synonym: "RNA transport from cytoplasm to nucleus" EXACT [] +synonym: "RNA-nucleus import" EXACT [] +is_a: GO:0050658 ! RNA transport +is_a: GO:0051170 ! import into nucleus + +[Term] +id: GO:0006405 +name: RNA export from nucleus +namespace: biological_process +def: "The directed movement of RNA from the nucleus to the cytoplasm." [GOC:ma] +synonym: "RNA export from cell nucleus" EXACT [] +synonym: "RNA export out of nucleus" EXACT [] +synonym: "RNA transport from nucleus to cytoplasm" EXACT [] +synonym: "RNA-nucleus export" EXACT [] +is_a: GO:0050658 ! RNA transport +is_a: GO:0051168 ! nuclear export + +[Term] +id: GO:0006406 +name: mRNA export from nucleus +namespace: biological_process +def: "The directed movement of mRNA from the nucleus to the cytoplasm." [GOC:ma] +synonym: "mRNA export from cell nucleus" EXACT [] +synonym: "mRNA export out of nucleus" EXACT [] +synonym: "mRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "mRNA-nucleus export" EXACT [] +is_a: GO:0006405 ! RNA export from nucleus +is_a: GO:0051028 ! mRNA transport +relationship: part_of GO:0010467 ! gene expression +relationship: part_of GO:0071427 ! mRNA-containing ribonucleoprotein complex export from nucleus + +[Term] +id: GO:0006407 +name: rRNA export from nucleus +namespace: biological_process +def: "The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins." [GOC:ma, GOC:mah] +synonym: "rRNA export from cell nucleus" EXACT [] +synonym: "rRNA export out of nucleus" EXACT [] +synonym: "rRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "rRNA-nucleus export" EXACT [] +is_a: GO:0051029 ! rRNA transport +is_a: GO:0097064 ! ncRNA export from nucleus +relationship: part_of GO:0042254 ! ribosome biogenesis +relationship: part_of GO:0071428 ! rRNA-containing ribonucleoprotein complex export from nucleus + +[Term] +id: GO:0006408 +name: snRNA export from nucleus +namespace: biological_process +def: "The directed movement of snRNA from the nucleus to the cytoplasm." [GOC:ma] +synonym: "snRNA export from cell nucleus" EXACT [] +synonym: "snRNA export out of nucleus" EXACT [] +synonym: "snRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "snRNA-nucleus export" EXACT [] +is_a: GO:0051030 ! snRNA transport +is_a: GO:0097064 ! ncRNA export from nucleus + +[Term] +id: GO:0006409 +name: tRNA export from nucleus +namespace: biological_process +def: "The directed movement of tRNA from the nucleus to the cytoplasm." [GOC:ma] +synonym: "tRNA export from cell nucleus" EXACT [] +synonym: "tRNA export out of nucleus" EXACT [] +synonym: "tRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "tRNA-nucleus export" EXACT [] +is_a: GO:0051031 ! tRNA transport +is_a: GO:0097064 ! ncRNA export from nucleus +relationship: part_of GO:0071431 ! tRNA-containing ribonucleoprotein complex export from nucleus + +[Term] +id: GO:0006410 +name: obsolete transcription, RNA-dependent +namespace: biological_process +def: "OBSOLETE. The cellular synthesis of DNA on a template of RNA." [GOC:jl] +comment: This term was obsoleted because the name and the definition mean two completely different things: 1) "transcription, RNA-dependent", i.e. RNA-dependent production of an RNA transcript and 2) "reverse transcription", i.e. RNA-dependent DNA synthesis. +synonym: "transcription, RNA-dependent" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006412 +name: translation +namespace: biological_process +alt_id: GO:0006416 +alt_id: GO:0006453 +alt_id: GO:0043037 +def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "protein anabolism" EXACT [] +synonym: "protein biosynthesis" EXACT [] +synonym: "protein biosynthetic process" EXACT [] +synonym: "protein formation" EXACT [] +synonym: "protein synthesis" EXACT [] +synonym: "protein translation" EXACT [] +xref: Wikipedia:Translation_(genetics) +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0044267 ! cellular protein metabolic process +relationship: has_part GO:0006414 ! translational elongation +relationship: part_of GO:0010467 ! gene expression + +[Term] +id: GO:0006413 +name: translational initiation +namespace: biological_process +alt_id: GO:0006440 +alt_id: GO:0006454 +def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X] +subset: goslim_yeast +synonym: "biopolymerisation" BROAD [] +synonym: "biopolymerization" BROAD [] +synonym: "protein synthesis initiation" BROAD [] +synonym: "translation initiation" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0006414 +name: translational elongation +namespace: biological_process +alt_id: GO:0006442 +alt_id: GO:0006455 +def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems] +subset: goslim_yeast +synonym: "protein synthesis elongation" BROAD [] +synonym: "translation elongation" EXACT [] +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0006415 +name: translational termination +namespace: biological_process +alt_id: GO:0006443 +alt_id: GO:0006456 +def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X] +synonym: "protein synthesis termination" BROAD [] +synonym: "translation termination" EXACT [] +synonym: "translational complex disassembly" EXACT [] +is_a: GO:0043624 ! cellular protein complex disassembly +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0006417 +name: regulation of translation +namespace: biological_process +alt_id: GO:0006445 +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] +subset: goslim_yeast +synonym: "regulation of protein anabolism" EXACT [] +synonym: "regulation of protein biosynthesis" EXACT [] +synonym: "regulation of protein formation" EXACT [] +synonym: "regulation of protein synthesis" EXACT [] +is_a: GO:0010608 ! posttranscriptional regulation of gene expression +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006412 ! translation +relationship: regulates GO:0006412 ! translation + +[Term] +id: GO:0006418 +name: tRNA aminoacylation for protein translation +namespace: biological_process +def: "The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis." [GOC:ma] +subset: goslim_yeast +synonym: "tRNA charging" NARROW [] +xref: MetaCyc:TRNA-CHARGING-PWY +is_a: GO:0043039 ! tRNA aminoacylation +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0006419 +name: alanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006420 +name: arginyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006421 +name: asparaginyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006422 +name: aspartyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA." [GOC:mah, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006423 +name: cysteinyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006424 +name: glutamyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006425 +name: glutaminyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006426 +name: glycyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006427 +name: histidyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006428 +name: isoleucyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006429 +name: leucyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006430 +name: lysyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006431 +name: methionyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006432 +name: phenylalanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006433 +name: prolyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA." [GOC:mah, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006434 +name: seryl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation +relationship: has_part GO:0097056 ! selenocysteinyl-tRNA(Sec) biosynthetic process + +[Term] +id: GO:0006435 +name: threonyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006436 +name: tryptophanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006437 +name: tyrosyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006438 +name: valyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification." [GOC:mcc, ISBN:0716730510] +is_a: GO:0006418 ! tRNA aminoacylation for protein translation + +[Term] +id: GO:0006439 +name: obsolete aminoacyl-tRNA hydrolase reaction +namespace: biological_process +def: "OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA." [ISBN:019879276X] +comment: This term was made obsolete because it represents a molecular function. +synonym: "aminoacyl-tRNA hydrolase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0004045 + +[Term] +id: GO:0006441 +name: obsolete binding to mRNA cap +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:hjd] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "binding to mRNA cap" EXACT [] +is_obsolete: true +consider: GO:0000339 + +[Term] +id: GO:0006446 +name: regulation of translational initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006413 ! translational initiation +relationship: regulates GO:0006413 ! translational initiation + +[Term] +id: GO:0006447 +name: regulation of translational initiation by iron +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron." [GOC:jl] +is_a: GO:0006446 ! regulation of translational initiation + +[Term] +id: GO:0006448 +name: regulation of translational elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators] +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006414 ! translational elongation +relationship: regulates GO:0006414 ! translational elongation + +[Term] +id: GO:0006449 +name: regulation of translational termination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006415 ! translational termination +relationship: regulates GO:0006415 ! translational termination + +[Term] +id: GO:0006450 +name: regulation of translational fidelity +namespace: biological_process +alt_id: GO:0000029 +def: "Any process that modulates the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] +synonym: "regulation of translational accuracy" EXACT [] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0006451 +name: translational readthrough +namespace: biological_process +def: "The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons." [GOC:jsg, PMID:11179232] +synonym: "natural nonsense suppression" RELATED [] +is_a: GO:0006414 ! translational elongation +is_a: GO:0006417 ! regulation of translation + +[Term] +id: GO:0006452 +name: translational frameshifting +namespace: biological_process +def: "A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon." [GOC:hjd, ISBN:0195094425] +xref: Wikipedia:Translational_frameshift +is_a: GO:0006414 ! translational elongation + +[Term] +id: GO:0006457 +name: protein folding +namespace: biological_process +alt_id: GO:0007022 +alt_id: GO:0007024 +alt_id: GO:0007025 +def: "The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure." [GOC:go_curators, GOC:rb] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "alpha-tubulin folding" NARROW [GOC:mah] +synonym: "beta-tubulin folding" NARROW [GOC:mah] +synonym: "chaperone activity" RELATED [] +synonym: "chaperonin ATPase activity" RELATED [] +synonym: "chaperonin-mediated tubulin folding" NARROW [GOC:mah] +synonym: "co-chaperone activity" RELATED [] +synonym: "co-chaperonin activity" RELATED [] +synonym: "glycoprotein-specific chaperone activity" RELATED [] +synonym: "non-chaperonin molecular chaperone ATPase activity" RELATED [] +synonym: "protein complex assembly, multichaperone pathway" RELATED [] +xref: Wikipedia:Protein_folding +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0006458 +name: 'de novo' protein folding +namespace: biological_process +def: "The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure." [GOC:mb] +synonym: "nascent chain protein folding" EXACT [] +is_a: GO:0006457 ! protein folding + +[Term] +id: GO:0006459 +name: obsolete binding unfolded ER proteins +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "binding unfolded ER proteins" EXACT [] +is_obsolete: true +consider: GO:0005783 +consider: GO:0051082 + +[Term] +id: GO:0006460 +name: obsolete peptidyl-prolyl isomerase B reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "peptidyl-prolyl isomerase B reaction" EXACT [] +is_obsolete: true +consider: GO:0003755 + +[Term] +id: GO:0006462 +name: obsolete protein complex assembly, multichaperone pathway +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the string was ambiguous and the original meaning of the term was hence unknown. +synonym: "protein complex assembly, multichaperone pathway" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051131 + +[Term] +id: GO:0006463 +name: steroid hormone receptor complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor." [GOC:jl, Wikipedia:Steroid_hormone_receptor] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0006464 +name: cellular protein modification process +namespace: biological_process +def: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:go_curators] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +synonym: "process resulting in protein modification" RELATED [] +synonym: "protein modification process" BROAD [GOC:bf, GOC:jl] +synonym: "protein tagging activity" RELATED [] +is_a: GO:0036211 ! protein modification process +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0006465 +name: signal peptide processing +namespace: biological_process +def: "The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell." [GOC:mah, ISBN:0815316194] +synonym: "leader peptide processing" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0016485 ! protein processing +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0006466 +name: obsolete protein disulfide-isomerase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it presents a molecular function. +synonym: "protein disulfide-isomerase reaction" EXACT [] +synonym: "protein disulphide-isomerase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0003756 + +[Term] +id: GO:0006468 +name: protein phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group on to a protein." [GOC:hb] +subset: goslim_yeast +synonym: "protein amino acid phosphorylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0016310 ! phosphorylation + +[Term] +id: GO:0006469 +name: negative regulation of protein kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity." [GOC:go_curators] +synonym: "down regulation of protein kinase activity" EXACT [] +synonym: "down-regulation of protein kinase activity" EXACT [] +synonym: "downregulation of protein kinase activity" EXACT [] +synonym: "inhibition of protein kinase activity" NARROW [] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0033673 ! negative regulation of kinase activity +is_a: GO:0045859 ! regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004672 ! protein kinase activity +relationship: negatively_regulates GO:0004672 ! protein kinase activity + +[Term] +id: GO:0006470 +name: protein dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphoric residues from a protein." [GOC:hb] +subset: goslim_yeast +synonym: "protein amino acid dephosphorylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0016311 ! dephosphorylation + +[Term] +id: GO:0006471 +name: protein ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of ADP-ribose to protein amino acids." [GOC:pr, RESID:AA0040, RESID:AA0168, RESID:AA0169, RESID:AA0231, RESID:AA0237, RESID:AA0295] +synonym: "protein amino acid ADP-ribosylation" EXACT [GOC:bf] +xref: RESID:AA0040 +xref: RESID:AA0168 +xref: RESID:AA0169 +xref: RESID:AA0231 +xref: RESID:AA0237 +xref: RESID:AA0295 +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0006473 +name: protein acetylation +namespace: biological_process +def: "The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ai] +synonym: "protein amino acid acetylation" EXACT [GOC:bf] +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0006474 +name: N-terminal protein amino acid acetylation +namespace: biological_process +def: "The acetylation of the N-terminal amino acid of proteins." [GOC:ai] +synonym: "N(alpha)-terminal acetylation" NARROW [PMID:11013267] +is_a: GO:0006473 ! protein acetylation +is_a: GO:0031365 ! N-terminal protein amino acid modification +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0006475 +name: internal protein amino acid acetylation +namespace: biological_process +def: "The addition of an acetyl group to a non-terminal amino acid in a protein." [GOC:mah] +is_a: GO:0006473 ! protein acetylation + +[Term] +id: GO:0006476 +name: protein deacetylation +namespace: biological_process +def: "The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ai] +synonym: "protein amino acid deacetylation" EXACT [GOC:bf] +is_a: GO:0035601 ! protein deacylation + +[Term] +id: GO:0006477 +name: protein sulfation +namespace: biological_process +def: "The addition of a sulfate group as an ester to a protein amino acid." [GOC:curators] +synonym: "protein amino acid sulfation" EXACT [GOC:bf] +synonym: "protein amino acid sulphation" EXACT [] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0051923 ! sulfation + +[Term] +id: GO:0006478 +name: peptidyl-tyrosine sulfation +namespace: biological_process +def: "The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine." [RESID:AA0172] +synonym: "peptidyl-tyrosine sulphation" EXACT [] +xref: RESID:AA0172 +is_a: GO:0006477 ! protein sulfation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0006479 +name: protein methylation +namespace: biological_process +def: "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." [GOC:ai] +synonym: "protein amino acid methylation" EXACT [GOC:bf] +is_a: GO:0008213 ! protein alkylation +is_a: GO:0043414 ! macromolecule methylation + +[Term] +id: GO:0006480 +name: N-terminal protein amino acid methylation +namespace: biological_process +def: "The methylation of the N-terminal amino acid of a protein." [GOC:ai] +is_a: GO:0006479 ! protein methylation +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0006481 +name: C-terminal protein methylation +namespace: biological_process +def: "The methylation of the C-terminal amino acid of a protein." [GOC:ai] +synonym: "C-terminal protein amino acid methylation" EXACT [GOC:bf] +is_a: GO:0006479 ! protein methylation +is_a: GO:0018410 ! C-terminal protein amino acid modification + +[Term] +id: GO:0006482 +name: protein demethylation +namespace: biological_process +def: "The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." [GOC:mah] +synonym: "protein amino acid demethylation" EXACT [GOC:bf] +is_a: GO:0008214 ! protein dealkylation +is_a: GO:0070988 ! demethylation + +[Term] +id: GO:0006483 +name: obsolete peptidyl-aspartic acid/asparagine hydroxylation +namespace: biological_process +def: "OBSOLETE. The hydroxylation of peptidyl-aspartic acid or asparagine." [GOC:ai] +comment: This term was made obsolete because it is a redundant grouping term. +synonym: "aspartic acid/asparagine hydroxylation" EXACT [] +synonym: "peptidyl-aspartic acid/asparagine hydroxylation" EXACT [] +is_obsolete: true +consider: GO:0042264 +consider: GO:0042265 + +[Term] +id: GO:0006484 +name: obsolete protein cysteine-thiol oxidation +namespace: biological_process +def: "OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine." [http://micro.magnet.fsu.edu/aminoacids/pages/cystine.html, http://www.indstate.edu/thcme/mwking/pentose-phosphate-pathway.html, RESID:AA0025] +comment: This term was made obsolete because it represents a single activity. +synonym: "protein cysteine-thiol oxidation" EXACT [] +is_obsolete: true +consider: GO:0003756 + +[Term] +id: GO:0006486 +name: protein glycosylation +namespace: biological_process +alt_id: GO:0065006 +def: "A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:curators, GOC:pr] +subset: goslim_pombe +subset: goslim_yeast +synonym: "protein amino acid glycosylation" EXACT [GOC:bf] +synonym: "protein-carbohydrate complex assembly" RELATED [] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0043413 ! macromolecule glycosylation +relationship: part_of GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0006487 +name: protein N-linked glycosylation +namespace: biological_process +def: "A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan." [GOC:pr, RESID:AA0151, RESID:AA0156, RESID:AA0327] +synonym: "N-glycan biosynthesis" RELATED [] +synonym: "N-glycan metabolism" RELATED [] +synonym: "protein amino acid N-linked glycosylation" EXACT [GOC:bf] +xref: RESID:AA0151 +xref: RESID:AA0156 +xref: RESID:AA0327 +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0006488 +name: dolichol-linked oligosaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P." [GOC:jl, ISBN:0471331309] +synonym: "dolichol-linked oligosaccharide anabolism" EXACT [] +synonym: "dolichol-linked oligosaccharide biosynthesis" EXACT [] +synonym: "dolichol-linked oligosaccharide formation" EXACT [] +synonym: "dolichol-linked oligosaccharide synthesis" EXACT [] +synonym: "N-linked glycan precursor biosynthesis" EXACT [PMID:8666161] +synonym: "N-linked glycan precursor biosynthetic process" EXACT [PMID:8666161] +synonym: "oligosaccharide-PP-dolichol assembly" EXACT [] +is_a: GO:0006490 ! oligosaccharide-lipid intermediate biosynthetic process +relationship: part_of GO:0006487 ! protein N-linked glycosylation + +[Term] +id: GO:0006489 +name: dolichyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative." [ISBN:0198506732] +synonym: "dolichyl diphosphate anabolism" EXACT [] +synonym: "dolichyl diphosphate biosynthesis" EXACT [] +synonym: "dolichyl diphosphate formation" EXACT [] +synonym: "dolichyl diphosphate synthesis" EXACT [] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0046465 ! dolichyl diphosphate metabolic process +relationship: part_of GO:0006488 ! dolichol-linked oligosaccharide biosynthetic process + +[Term] +id: GO:0006490 +name: oligosaccharide-lipid intermediate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation." [GOC:dph, GOC:hjd, GOC:isa_complete, GOC:pr, GOC:rb] +synonym: "oligosaccharide-lipid intermediate assembly" NARROW [GOC:pr] +synonym: "oligosaccharide-lipid intermediate biosynthetic process" NARROW [GOC:pr] +is_a: GO:0044255 ! cellular lipid metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0006491 +name: N-glycan processing +namespace: biological_process +alt_id: GO:0006492 +def: "The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking." [ISBN:0879695595, PMID:12736198] +synonym: "glycoprotein trimming involved in glycoprotein maturation" NARROW [] +synonym: "N-linked glycoprotein maturation" EXACT [] +is_a: GO:0009100 ! glycoprotein metabolic process + +[Term] +id: GO:0006493 +name: protein O-linked glycosylation +namespace: biological_process +def: "A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan." [GOC:pr, ISBN:0879695595, RESID:AA0153, RESID:AA0154, RESID:AA0155, RESID:AA0157, RESID:AA0212] +synonym: "protein amino acid O-linked glycosylation" EXACT [GOC:bf] +xref: RESID:AA0153 +xref: RESID:AA0154 +xref: RESID:AA0155 +xref: RESID:AA0157 +xref: RESID:AA0212 +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0006494 +name: obsolete protein amino acid terminal glycosylation +namespace: biological_process +def: "OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide." [GOC:jsg] +comment: This term was made obsolete because the term name is ambiguous. +synonym: "protein amino acid terminal glycosylation" EXACT [] +is_obsolete: true +consider: GO:0006486 + +[Term] +id: GO:0006495 +name: obsolete terminal O-glycosylation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators, GOC:jsg] +comment: This term was made obsolete because there is no evidence for the existence of this process. +synonym: "terminal O-glycosylation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006496 +name: obsolete protein amino acid terminal N-glycosylation +namespace: biological_process +def: "OBSOLETE. The glycosylation of a nitrogen atom of a free alpha amino terminal of a peptide." [GOC:jsg] +comment: This term was made obsolete because the term name is ambiguous. +synonym: "protein amino acid terminal N-glycosylation" EXACT [] +is_obsolete: true +consider: GO:0006487 +consider: GO:0035629 + +[Term] +id: GO:0006497 +name: protein lipidation +namespace: biological_process +alt_id: GO:0042050 +def: "The covalent attachment of lipid groups to an amino acid in a protein." [GOC:jl] +comment: For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children. +subset: goslim_drosophila +subset: goslim_yeast +synonym: "lipid:protein modification" EXACT [] +synonym: "protein amino acid lipidation" EXACT [GOC:bf] +xref: RESID:AA0059 +xref: RESID:AA0060 +xref: RESID:AA0077 +xref: RESID:AA0078 +xref: RESID:AA0079 +xref: RESID:AA0080 +xref: RESID:AA0102 +xref: RESID:AA0103 +xref: RESID:AA0104 +xref: RESID:AA0106 +xref: RESID:AA0107 +xref: RESID:AA0158 +xref: RESID:AA0159 +xref: RESID:AA0160 +xref: RESID:AA0161 +xref: RESID:AA0162 +xref: RESID:AA0163 +xref: RESID:AA0166 +xref: RESID:AA0223 +xref: RESID:AA0290 +xref: RESID:AA0307 +xref: RESID:AA0308 +xref: RESID:AA0309 +xref: RESID:AA0316 +is_a: GO:0006464 ! cellular protein modification process +relationship: part_of GO:0042158 ! lipoprotein biosynthetic process + +[Term] +id: GO:0006498 +name: N-terminal protein lipidation +namespace: biological_process +def: "The covalent attachment of a lipid group to the amino terminus of a protein." [GOC:jl] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0006499 +name: N-terminal protein myristoylation +namespace: biological_process +def: "The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein." [GOC:mah] +is_a: GO:0006498 ! N-terminal protein lipidation +is_a: GO:0018377 ! protein myristoylation + +[Term] +id: GO:0006500 +name: N-terminal protein palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:mah] +is_a: GO:0006498 ! N-terminal protein lipidation +is_a: GO:0018345 ! protein palmitoylation + +[Term] +id: GO:0006501 +name: C-terminal protein lipidation +namespace: biological_process +def: "The covalent attachment of a lipid group to the carboxy-terminus of a protein." [GOC:jl] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0018410 ! C-terminal protein amino acid modification + +[Term] +id: GO:0006502 +name: obsolete C-terminal protein prenylation +namespace: biological_process +def: "OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added." [GOC:jl] +comment: This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. +synonym: "C-terminal protein prenylation" EXACT [] +is_obsolete: true +replaced_by: GO:0018342 + +[Term] +id: GO:0006503 +name: obsolete C-terminal protein farnesylation +namespace: biological_process +def: "OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein." [GOC:jl] +comment: This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. +synonym: "C-terminal protein farnesylation" EXACT [] +is_obsolete: true +replaced_by: GO:0018343 + +[Term] +id: GO:0006504 +name: obsolete C-terminal protein geranylgeranylation +namespace: biological_process +def: "OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein." [GOC:jl] +comment: This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. +synonym: "C-terminal protein geranylgeranylation" EXACT [] +is_obsolete: true +replaced_by: GO:0018344 + +[Term] +id: GO:0006505 +name: GPI anchor metabolic process +namespace: biological_process +alt_id: GO:0046472 +def: "The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain." [ISBN:0198506732] +synonym: "glycosylphosphatidylinositol metabolic process" EXACT [] +synonym: "glycosylphosphatidylinositol metabolism" EXACT [] +synonym: "GPI anchor metabolism" EXACT [] +synonym: "GPI/GSI anchor metabolic process" BROAD [] +synonym: "GPI/GSI anchor metabolism" BROAD [] +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0046488 ! phosphatidylinositol metabolic process + +[Term] +id: GO:0006506 +name: GPI anchor biosynthetic process +namespace: biological_process +alt_id: GO:0015998 +def: "The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage." [GOC:go_curators, ISBN:0198547684] +synonym: "glycosylphosphatidylinositol biosynthesis" EXACT [] +synonym: "glycosylphosphatidylinositol biosynthetic process" EXACT [] +synonym: "GPI anchor anabolism" EXACT [] +synonym: "GPI anchor biosynthesis" EXACT [] +synonym: "GPI anchor formation" EXACT [] +synonym: "GPI anchor synthesis" EXACT [] +synonym: "GPI/GSI anchor biosynthesis" BROAD [] +synonym: "GPI/GSI anchor biosynthetic process" BROAD [] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0006505 ! GPI anchor metabolic process +is_a: GO:0006661 ! phosphatidylinositol biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process + +[Term] +id: GO:0006507 +name: GPI anchor release +namespace: biological_process +def: "The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane." [GOC:mah, PMID:18811934] +is_a: GO:0006505 ! GPI anchor metabolic process + +[Term] +id: GO:0006508 +name: proteolysis +namespace: biological_process +def: "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." [GOC:bf, GOC:mah] +comment: This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing. +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +synonym: "ATP-dependent proteolysis" NARROW [GOC:mah] +synonym: "peptidolysis" EXACT [] +xref: Wikipedia:Proteolysis +is_a: GO:0019538 ! protein metabolic process + +[Term] +id: GO:0006509 +name: membrane protein ectodomain proteolysis +namespace: biological_process +def: "The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)." [GOC:jl, http://www.copewithcytokines.de/] +synonym: "ectoderm shedding" BROAD [GOC:pm, PMID:12096138, PMID:15672459, PMID:18419754] +synonym: "ectodomain cleavage" EXACT [PMID:18757500] +synonym: "membrane protein solubilization" RELATED [] +synonym: "receptor shedding" RELATED [] +is_a: GO:0033619 ! membrane protein proteolysis + +[Term] +id: GO:0006510 +name: obsolete ATP-dependent proteolysis +namespace: biological_process +def: "OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP." [GOC:jl] +comment: This term was made obsolete because it represents a molecular function. +synonym: "ATP-dependent peptidolysis" EXACT [] +synonym: "ATP-dependent proteolysis" EXACT [] +is_obsolete: true +replaced_by: GO:0004176 +consider: GO:0006508 +consider: GO:0016485 +consider: GO:0051603 + +[Term] +id: GO:0006511 +name: ubiquitin-dependent protein catabolic process +namespace: biological_process +alt_id: GO:0042787 +alt_id: GO:0043432 +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein." [GOC:go_curators] +synonym: "myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown" NARROW [] +synonym: "myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism" NARROW [] +synonym: "myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation" NARROW [] +synonym: "protein degradation tagging activity" BROAD [] +synonym: "protein ubiquitination during ubiquitin-dependent protein breakdown" NARROW [] +synonym: "protein ubiquitination during ubiquitin-dependent protein catabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "protein ubiquitination during ubiquitin-dependent protein catabolism" NARROW [] +synonym: "protein ubiquitination during ubiquitin-dependent protein degradation" NARROW [] +synonym: "protein ubiquitination involved in ubiquitin-dependent protein catabolic process" RELATED [] +synonym: "protein ubiquitinylation during ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "protein ubiquitinylation during ubiquitin-dependent protein catabolism" NARROW [] +synonym: "protein ubiquitylation during ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "protein ubiquitylation during ubiquitin-dependent protein catabolism" NARROW [] +synonym: "ubiquitin-dependent protein breakdown" EXACT [] +synonym: "ubiquitin-dependent protein catabolism" EXACT [] +synonym: "ubiquitin-dependent protein degradation" EXACT [] +synonym: "ubiquitin-dependent proteolysis" EXACT [] +is_a: GO:0019941 ! modification-dependent protein catabolic process + +[Term] +id: GO:0006512 +name: obsolete ubiquitin cycle +namespace: biological_process +def: "OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein." [PMID:11917093] +comment: This term was made obsolete because it implies that every protein that is ubiquitinated is also subsequently deubiquinitated, which is not true. Also, the process ontology does not include analogous terms for other small modifiers. +synonym: "ubiquitin cycle" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006513 +name: protein monoubiquitination +namespace: biological_process +def: "Addition of a single ubiquitin group to a protein." [GOC:ai] +synonym: "protein monoubiquitinylation" EXACT [] +synonym: "protein monoubiquitylation" EXACT [] +is_a: GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0006515 +name: protein quality control for misfolded or incompletely synthesized proteins +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins." [GOC:jl] +synonym: "degradation of misfolded or incompletely synthesized proteins" EXACT [] +synonym: "misfolded or incompletely synthesized protein breakdown" EXACT [] +synonym: "misfolded or incompletely synthesized protein catabolic process" EXACT [] +synonym: "misfolded or incompletely synthesized protein catabolism" EXACT [] +synonym: "misfolded or incompletely synthesized protein degradation" EXACT [] +synonym: "protein quality control (PQC)" EXACT [] +synonym: "protein quality control by the ubiquitin-proteasome system" BROAD [] +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process + +[Term] +id: GO:0006516 +name: glycoprotein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] +synonym: "glycoprotein breakdown" EXACT [] +synonym: "glycoprotein catabolism" EXACT [] +synonym: "glycoprotein degradation" EXACT [] +is_a: GO:0009100 ! glycoprotein metabolic process +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0006517 +name: protein deglycosylation +namespace: biological_process +def: "The removal of sugar residues from a glycosylated protein." [GOC:mah] +synonym: "glycoprotein deglycosylation" EXACT [] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0009100 ! glycoprotein metabolic process + +[Term] +id: GO:0006518 +name: peptide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] +subset: goslim_pir +synonym: "peptide metabolism" EXACT [] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006520 +name: cellular amino acid metabolic process +namespace: biological_process +alt_id: GO:0006519 +def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "amino acid and derivative metabolism" EXACT [] +synonym: "amino acid metabolic process" EXACT [] +synonym: "cellular amino acid and derivative metabolic process" EXACT [] +synonym: "cellular amino acid metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0044238 ! primary metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006521 +name: regulation of cellular amino acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] +synonym: "regulation of amino acid metabolism" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006520 ! cellular amino acid metabolic process +relationship: regulates GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0006522 +name: alanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alanine, 2-aminopropanoic acid." [GOC:go_curators] +synonym: "alanine metabolism" EXACT [] +is_a: GO:0009078 ! pyruvate family amino acid metabolic process + +[Term] +id: GO:0006523 +name: alanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid." [GOC:go_curators] +synonym: "alanine anabolism" EXACT [] +synonym: "alanine biosynthesis" EXACT [] +synonym: "alanine formation" EXACT [] +synonym: "alanine synthesis" EXACT [] +is_a: GO:0006522 ! alanine metabolic process +is_a: GO:0009079 ! pyruvate family amino acid biosynthetic process + +[Term] +id: GO:0006524 +name: alanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid." [GOC:go_curators] +synonym: "alanine breakdown" EXACT [] +synonym: "alanine catabolism" EXACT [] +synonym: "alanine degradation" EXACT [] +is_a: GO:0006522 ! alanine metabolic process +is_a: GO:0009080 ! pyruvate family amino acid catabolic process + +[Term] +id: GO:0006525 +name: arginine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid." [GOC:go_curators] +synonym: "arginine metabolism" EXACT [] +xref: Wikipedia:Arginine +is_a: GO:0009064 ! glutamine family amino acid metabolic process + +[Term] +id: GO:0006526 +name: arginine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid." [ISBN:0198506732] +synonym: "arginine anabolism" EXACT [] +synonym: "arginine biosynthesis" EXACT [] +synonym: "arginine formation" EXACT [] +synonym: "arginine synthesis" EXACT [] +xref: MetaCyc:ARGININE-SYN4-PWY +xref: MetaCyc:ARGSYN-PWY +xref: MetaCyc:ARGSYNBSUB-PWY +is_a: GO:0006525 ! arginine metabolic process +is_a: GO:0009084 ! glutamine family amino acid biosynthetic process + +[Term] +id: GO:0006527 +name: arginine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid." [GOC:go_curators] +synonym: "arginine breakdown" EXACT [] +synonym: "arginine catabolism" EXACT [] +synonym: "arginine degradation" EXACT [] +is_a: GO:0006525 ! arginine metabolic process +is_a: GO:0009065 ! glutamine family amino acid catabolic process + +[Term] +id: GO:0006528 +name: asparagine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid." [GOC:go_curators] +synonym: "asparagine metabolism" EXACT [] +xref: MetaCyc:ASPARAGINESYN-PWY +is_a: GO:0009066 ! aspartate family amino acid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0006529 +name: asparagine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid." [GOC:go_curators] +synonym: "asparagine anabolism" EXACT [] +synonym: "asparagine biosynthesis" EXACT [] +synonym: "asparagine formation" EXACT [] +synonym: "asparagine synthesis" EXACT [] +is_a: GO:0006528 ! asparagine metabolic process +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0006530 +name: asparagine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid." [GOC:go_curators] +synonym: "asparagine breakdown" EXACT [] +synonym: "asparagine catabolism" EXACT [] +synonym: "asparagine degradation" EXACT [] +is_a: GO:0006528 ! asparagine metabolic process +is_a: GO:0009065 ! glutamine family amino acid catabolic process +is_a: GO:0009068 ! aspartate family amino acid catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0006531 +name: aspartate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid." [GOC:go_curators, ISBN:0198506732] +synonym: "aspartate metabolism" EXACT [] +is_a: GO:0009066 ! aspartate family amino acid metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006532 +name: aspartate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid." [GOC:go_curators, ISBN:0198506732] +synonym: "aspartate anabolism" EXACT [] +synonym: "aspartate biosynthesis" EXACT [] +synonym: "aspartate formation" EXACT [] +synonym: "aspartate synthesis" EXACT [] +is_a: GO:0006531 ! aspartate metabolic process +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0006533 +name: aspartate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid." [GOC:go_curators, ISBN:0198506732] +synonym: "aspartate breakdown" EXACT [] +synonym: "aspartate catabolism" EXACT [] +synonym: "aspartate degradation" EXACT [] +is_a: GO:0006531 ! aspartate metabolic process +is_a: GO:0009068 ! aspartate family amino acid catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0006534 +name: cysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators] +synonym: "cysteine metabolism" EXACT [] +xref: Wikipedia:Cysteine_metabolism +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0009069 ! serine family amino acid metabolic process + +[Term] +id: GO:0006535 +name: cysteine biosynthetic process from serine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine." [GOC:go_curators] +synonym: "cysteine anabolism from serine" EXACT [] +synonym: "cysteine formation from serine" EXACT [] +synonym: "cysteine synthesis from serine" EXACT [] +xref: MetaCyc:CYSTSYN-PWY +is_a: GO:0006563 ! L-serine metabolic process +is_a: GO:0019344 ! cysteine biosynthetic process + +[Term] +id: GO:0006536 +name: glutamate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid." [GOC:go_curators] +synonym: "glutamate metabolism" EXACT [] +synonym: "glutamic acid metabolic process" EXACT [] +synonym: "glutamic acid metabolism" EXACT [] +xref: Wikipedia:Glutamic_acid +is_a: GO:0009064 ! glutamine family amino acid metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0006537 +name: glutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid." [GOC:go_curators] +synonym: "glutamate anabolism" EXACT [] +synonym: "glutamate biosynthesis" EXACT [] +synonym: "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)" NARROW [] +synonym: "glutamate biosynthesis, using glutamate synthase (NADPH)" NARROW [] +synonym: "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)" NARROW [] +synonym: "glutamate biosynthetic process, using glutamate synthase (NADPH)" NARROW [] +synonym: "glutamate formation" EXACT [] +synonym: "glutamate synthesis" EXACT [] +synonym: "glutamic acid biosynthesis" EXACT [] +synonym: "glutamic acid biosynthetic process" EXACT [] +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0009084 ! glutamine family amino acid biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0006538 +name: glutamate catabolic process +namespace: biological_process +alt_id: GO:0019459 +def: "The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid." [GOC:go_curators] +synonym: "glutamate breakdown" EXACT [] +synonym: "glutamate catabolism" EXACT [] +synonym: "glutamate deamidation" RELATED [] +synonym: "glutamate degradation" EXACT [] +synonym: "glutamic acid catabolic process" EXACT [] +synonym: "glutamic acid catabolism" EXACT [] +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0009065 ! glutamine family amino acid catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0006539 +name: glutamate catabolic process via 2-oxoglutarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate." [GOC:go_curators] +synonym: "glutamate breakdown via 2-oxoglutarate" EXACT [] +synonym: "glutamate catabolic process via 2-ketoglutarate" EXACT [] +synonym: "glutamate catabolic process via alpha-ketoglutarate" EXACT [] +synonym: "glutamate catabolic process via alpha-oxoglutarate" EXACT [] +synonym: "glutamate catabolism via 2-ketoglutarate" EXACT [] +synonym: "glutamate catabolism via alpha-ketoglutarate" EXACT [] +synonym: "glutamate catabolism via alpha-oxoglutarate" EXACT [] +synonym: "glutamate degradation via 2-oxoglutarate" EXACT [] +xref: MetaCyc:P162-PWY +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0006538 ! glutamate catabolic process + +[Term] +id: GO:0006540 +name: glutamate decarboxylation to succinate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes." [PMID:12740438] +comment: Note that the third step in this pathway (conversion of succinate semialdehyde to succinate) can be catalyzed by NAD-dependent or NADP-dependent succinate semialdehyde dehydrogenase (EC:1.2.1.24 and EC:1.2.1.79, respectively). +synonym: "4-aminobutyrate shunt" EXACT [] +synonym: "degradation of glutamate to succinate through GABA" EXACT [MetaCyc:GLUDEG-I-PWY] +synonym: "GABA shunt" EXACT [] +synonym: "gamma-aminobutyrate shunt" EXACT [] +synonym: "glutamate degradation via 4-aminobutyrate" EXACT [MetaCyc:GLUDEG-I-PWY] +synonym: "glutamate degradation via GABA" EXACT [MetaCyc:GLUDEG-I-PWY] +xref: MetaCyc:GLUDEG-I-PWY +xref: MetaCyc:PWY-4321 +xref: MetaCyc:PWY3O-210 +is_a: GO:0006538 ! glutamate catabolic process +relationship: has_part GO:0003867 ! 4-aminobutyrate transaminase activity +relationship: has_part GO:0004351 ! glutamate decarboxylase activity + +[Term] +id: GO:0006541 +name: glutamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid." [GOC:ai] +synonym: "glutamine metabolism" EXACT [] +is_a: GO:0009064 ! glutamine family amino acid metabolic process + +[Term] +id: GO:0006542 +name: glutamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid." [GOC:ai] +synonym: "glutamine anabolism" EXACT [] +synonym: "glutamine biosynthesis" EXACT [] +synonym: "glutamine formation" EXACT [] +synonym: "glutamine synthesis" EXACT [] +xref: MetaCyc:GLNSYN-PWY +is_a: GO:0006541 ! glutamine metabolic process +is_a: GO:0009084 ! glutamine family amino acid biosynthetic process + +[Term] +id: GO:0006543 +name: glutamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid." [GOC:ai] +synonym: "glutamine breakdown" EXACT [] +synonym: "glutamine catabolism" EXACT [] +synonym: "glutamine degradation" EXACT [] +is_a: GO:0006541 ! glutamine metabolic process +is_a: GO:0009065 ! glutamine family amino acid catabolic process + +[Term] +id: GO:0006544 +name: glycine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycine, aminoethanoic acid." [GOC:go_curators] +synonym: "glycine metabolism" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process + +[Term] +id: GO:0006545 +name: glycine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid." [GOC:go_curators] +synonym: "glycine anabolism" EXACT [] +synonym: "glycine biosynthesis" EXACT [] +synonym: "glycine formation" EXACT [] +synonym: "glycine synthesis" EXACT [] +xref: MetaCyc:GLYCINE-SYN2-PWY +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0009070 ! serine family amino acid biosynthetic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process + +[Term] +id: GO:0006546 +name: glycine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid." [GOC:go_curators] +synonym: "glycine breakdown" EXACT [] +synonym: "glycine catabolism" EXACT [] +synonym: "glycine degradation" EXACT [] +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0009071 ! serine family amino acid catabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0006547 +name: histidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:go_curators] +synonym: "histidine metabolism" EXACT [] +xref: Wikipedia:Histidine +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0052803 ! imidazole-containing compound metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006548 +name: histidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:go_curators] +synonym: "histidine breakdown" EXACT [] +synonym: "histidine catabolism" EXACT [] +synonym: "histidine degradation" EXACT [] +is_a: GO:0006547 ! histidine metabolic process +is_a: GO:0009074 ! aromatic amino acid family catabolic process +is_a: GO:0052805 ! imidazole-containing compound catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006549 +name: isoleucine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai] +synonym: "isoleucine metabolism" EXACT [] +is_a: GO:0009081 ! branched-chain amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006550 +name: isoleucine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai] +synonym: "isoleucine breakdown" EXACT [] +synonym: "isoleucine catabolism" EXACT [] +synonym: "isoleucine degradation" EXACT [] +xref: MetaCyc:ILEUDEG-PWY +is_a: GO:0006549 ! isoleucine metabolic process +is_a: GO:0009083 ! branched-chain amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006551 +name: leucine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid." [GOC:ai] +synonym: "leucine metabolism" EXACT [] +is_a: GO:0009081 ! branched-chain amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006552 +name: leucine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid." [GOC:ai] +synonym: "leucine breakdown" EXACT [] +synonym: "leucine catabolism" EXACT [] +synonym: "leucine degradation" EXACT [] +xref: MetaCyc:LEU-DEG2-PWY +is_a: GO:0006551 ! leucine metabolic process +is_a: GO:0009083 ! branched-chain amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006553 +name: lysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid." [GOC:go_curators] +synonym: "lysine metabolism" EXACT [] +xref: Wikipedia:Lysine +is_a: GO:0009066 ! aspartate family amino acid metabolic process + +[Term] +id: GO:0006554 +name: lysine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators] +synonym: "lysine breakdown" EXACT [] +synonym: "lysine catabolism" EXACT [] +synonym: "lysine degradation" EXACT [] +is_a: GO:0006553 ! lysine metabolic process +is_a: GO:0009068 ! aspartate family amino acid catabolic process + +[Term] +id: GO:0006555 +name: methionine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "methionine and threonine metabolic process" BROAD [] +synonym: "methionine and threonine metabolism" BROAD [] +synonym: "methionine metabolism" EXACT [] +xref: UM-BBD_pathwayID:met +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0009066 ! aspartate family amino acid metabolic process + +[Term] +id: GO:0006556 +name: S-adenosylmethionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism." [GOC:go_curators, ISBN:0198506732] +synonym: "S-adenosyl methionine biosynthesis" EXACT [] +synonym: "S-adenosyl methionine biosynthetic process" EXACT [] +synonym: "S-adenosylmethionine anabolism" EXACT [] +synonym: "S-adenosylmethionine biosynthesis" EXACT [] +synonym: "S-adenosylmethionine formation" EXACT [] +synonym: "S-adenosylmethionine synthesis" EXACT [] +synonym: "SAM biosynthetic process" EXACT [] +xref: MetaCyc:SAM-PWY +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0046500 ! S-adenosylmethionine metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0006557 +name: S-adenosylmethioninamine biosynthetic process +namespace: biological_process +alt_id: GO:0006745 +def: "The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt." [GOC:mah, MetaCyc:S-ADENOSYLMETHIONINAMINE] +synonym: "S-adenosylmethioninamine anabolism" EXACT [] +synonym: "S-adenosylmethioninamine biosynthesis" EXACT [] +synonym: "S-adenosylmethioninamine formation" EXACT [] +synonym: "S-adenosylmethioninamine synthesis" EXACT [] +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process +is_a: GO:0046499 ! S-adenosylmethioninamine metabolic process + +[Term] +id: GO:0006558 +name: L-phenylalanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid." [GOC:jsg, GOC:mah] +synonym: "L-phenylalanine metabolism" EXACT [] +synonym: "phenylalanine metabolic process" BROAD [] +synonym: "phenylalanine metabolism" BROAD [] +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1902221 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process + +[Term] +id: GO:0006559 +name: L-phenylalanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid." [GOC:go_curators] +synonym: "L-phenylalanine breakdown" EXACT [] +synonym: "L-phenylalanine catabolism" EXACT [] +synonym: "L-phenylalanine degradation" EXACT [] +synonym: "phenylalanine catabolic process" BROAD [] +synonym: "phenylalanine catabolism" BROAD [] +is_a: GO:0006558 ! L-phenylalanine metabolic process +is_a: GO:0009074 ! aromatic amino acid family catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1902222 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process + +[Term] +id: GO:0006560 +name: proline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "proline metabolism" EXACT [] +is_a: GO:0009064 ! glutamine family amino acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0006561 +name: proline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [ISBN:0198506732] +synonym: "proline anabolism" EXACT [] +synonym: "proline biosynthesis" EXACT [] +synonym: "proline formation" EXACT [] +synonym: "proline synthesis" EXACT [] +xref: MetaCyc:PROSYN-PWY +xref: MetaCyc:PWY-3341 +is_a: GO:0006560 ! proline metabolic process +is_a: GO:0009084 ! glutamine family amino acid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0006562 +name: proline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "proline breakdown" EXACT [] +synonym: "proline catabolism" EXACT [] +synonym: "proline degradation" EXACT [] +is_a: GO:0006560 ! proline metabolic process +is_a: GO:0009065 ! glutamine family amino acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0006563 +name: L-serine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg] +synonym: "L-serine metabolism" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process + +[Term] +id: GO:0006564 +name: L-serine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg] +synonym: "L-serine anabolism" EXACT [] +synonym: "L-serine biosynthesis" EXACT [] +synonym: "L-serine formation" EXACT [] +synonym: "L-serine synthesis" EXACT [] +xref: MetaCyc:SERSYN-PWY +is_a: GO:0006563 ! L-serine metabolic process +is_a: GO:0009070 ! serine family amino acid biosynthetic process + +[Term] +id: GO:0006565 +name: L-serine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg] +synonym: "L-serine breakdown" EXACT [] +synonym: "L-serine catabolism" EXACT [] +synonym: "L-serine degradation" EXACT [] +xref: MetaCyc:SERDEG-PWY +is_a: GO:0006563 ! L-serine metabolic process +is_a: GO:0009071 ! serine family amino acid catabolic process + +[Term] +id: GO:0006566 +name: threonine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "methionine and threonine metabolic process" BROAD [] +synonym: "methionine and threonine metabolism" BROAD [] +synonym: "threonine metabolism" EXACT [] +xref: UM-BBD_pathwayID:met +is_a: GO:0009066 ! aspartate family amino acid metabolic process + +[Term] +id: GO:0006567 +name: threonine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "threonine breakdown" EXACT [] +synonym: "threonine catabolism" EXACT [] +synonym: "threonine degradation" EXACT [] +xref: MetaCyc:THREOCAT-PWY +xref: UM-BBD_pathwayID:met +is_a: GO:0006566 ! threonine metabolic process +is_a: GO:0009068 ! aspartate family amino acid catabolic process + +[Term] +id: GO:0006568 +name: tryptophan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684] +synonym: "tryptophan metabolism" EXACT [] +xref: Wikipedia:Tryptophan +is_a: GO:0006586 ! indolalkylamine metabolic process +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006569 +name: tryptophan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684] +synonym: "tryptophan breakdown" EXACT [] +synonym: "tryptophan catabolic process, using tryptophanase" NARROW [] +synonym: "tryptophan catabolism" EXACT [] +synonym: "tryptophan catabolism, using tryptophanase" NARROW [] +synonym: "tryptophan degradation" EXACT [] +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0009074 ! aromatic amino acid family catabolic process +is_a: GO:0046218 ! indolalkylamine catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006570 +name: tyrosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:go_curators] +synonym: "tyrosine metabolism" EXACT [] +xref: UM-BBD_pathwayID:tyr +xref: Wikipedia:Tyrosine +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006571 +name: tyrosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:sm] +synonym: "tyrosine anabolism" EXACT [] +synonym: "tyrosine biosynthesis" EXACT [] +synonym: "tyrosine formation" EXACT [] +synonym: "tyrosine synthesis" EXACT [] +xref: MetaCyc:PWY-3461 +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0006572 +name: tyrosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:go_curators] +synonym: "tyrosine breakdown" EXACT [] +synonym: "tyrosine catabolism" EXACT [] +synonym: "tyrosine degradation" EXACT [] +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0009074 ! aromatic amino acid family catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006573 +name: valine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid." [GOC:ai] +synonym: "valine metabolism" EXACT [] +is_a: GO:0009081 ! branched-chain amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006574 +name: valine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid." [GOC:ai] +synonym: "valine breakdown" EXACT [] +synonym: "valine catabolism" EXACT [] +synonym: "valine degradation" EXACT [] +xref: MetaCyc:VALDEG-PWY +is_a: GO:0006573 ! valine metabolic process +is_a: GO:0009083 ! branched-chain amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006575 +name: cellular modified amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents." [GOC:ai] +synonym: "amino acid derivative metabolic process" EXACT [] +synonym: "cellular amino acid derivative metabolic process" EXACT [] +synonym: "cellular amino acid derivative metabolism" EXACT [] +synonym: "cellular modified amino acid metabolism" EXACT [GOC:mah] +synonym: "modified amino acid metabolic process" EXACT [GOC:mah] +synonym: "modified amino acid metabolism" EXACT [GOC:mah] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006576 +name: cellular biogenic amine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] +synonym: "biogenic amine metabolism" EXACT [] +is_a: GO:0044106 ! cellular amine metabolic process + +[Term] +id: GO:0006577 +name: amino-acid betaine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid." [GOC:mah, ISBN:0198506732] +synonym: "betaine metabolic process" EXACT [] +synonym: "betaine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0006578 +name: amino-acid betaine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid." [GOC:mah, ISBN:0198506732] +synonym: "betaine anabolism" EXACT [] +synonym: "betaine biosynthesis" EXACT [] +synonym: "betaine biosynthetic process" EXACT [] +synonym: "betaine formation" EXACT [] +synonym: "betaine synthesis" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process + +[Term] +id: GO:0006579 +name: amino-acid betaine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid." [GOC:mah, ISBN:0198506732] +synonym: "betaine breakdown" EXACT [] +synonym: "betaine catabolic process" EXACT [] +synonym: "betaine catabolism" EXACT [] +synonym: "betaine degradation" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process + +[Term] +id: GO:0006580 +name: ethanolamine metabolic process +namespace: biological_process +alt_id: GO:0006645 +def: "The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)." [ISBN:0192800981] +synonym: "ethanolamine metabolism" EXACT [] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042439 ! ethanolamine-containing compound metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0006581 +name: acetylcholine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] +synonym: "acetylcholine breakdown" EXACT [] +synonym: "acetylcholine catabolism" EXACT [] +synonym: "acetylcholine degradation" EXACT [] +is_a: GO:0008291 ! acetylcholine metabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0006582 +name: melanin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." [GOC:go_curators] +synonym: "melanin metabolism" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0006583 +name: melanin biosynthetic process from tyrosine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine." [GOC:go_curators] +synonym: "melanin anabolism from tyrosine" EXACT [] +synonym: "melanin formation from tyrosine" EXACT [] +synonym: "melanin synthesis from tyrosine" EXACT [] +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0042438 ! melanin biosynthetic process + +[Term] +id: GO:0006584 +name: catecholamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] +synonym: "catecholamine metabolism" EXACT [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006585 +name: dopamine biosynthetic process from tyrosine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine." [GOC:bf, GOC:jl, ISBN:0198506732] +synonym: "dopamine anabolism from tyrosine" EXACT [] +synonym: "dopamine formation from tyrosine" EXACT [] +synonym: "dopamine synthesis from tyrosine" EXACT [] +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0042416 ! dopamine biosynthetic process + +[Term] +id: GO:0006586 +name: indolalkylamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] +synonym: "indolalkylamine metabolism" EXACT [] +synonym: "indolamine metabolic process" BROAD [] +synonym: "indolamine metabolism" BROAD [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process + +[Term] +id: GO:0006587 +name: serotonin biosynthetic process from tryptophan +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] +synonym: "serotonin anabolism from tryptophan" EXACT [] +synonym: "serotonin formation from tryptophan" EXACT [] +synonym: "serotonin synthesis from tryptophan" EXACT [] +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0042427 ! serotonin biosynthetic process + +[Term] +id: GO:0006588 +name: activation of tryptophan 5-monooxygenase activity +namespace: biological_process +def: "The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity." [GOC:dph, GOC:tb] +synonym: "tryptophan hydroxylase activation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032770 ! positive regulation of monooxygenase activity +relationship: part_of GO:0006587 ! serotonin biosynthetic process from tryptophan + +[Term] +id: GO:0006589 +name: octopamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." [ISBN:0198506732] +synonym: "octopamine anabolism" EXACT [] +synonym: "octopamine biosynthesis" EXACT [] +synonym: "octopamine formation" EXACT [] +synonym: "octopamine synthesis" EXACT [] +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0046333 ! octopamine metabolic process + +[Term] +id: GO:0006590 +name: thyroid hormone generation +namespace: biological_process +def: "The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones." [GOC:jl, ISBN:0716720094] +comment: Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because thyroid hormones can only be formed by the proteolysis of a larger molecule (see term definition). The word 'generation' is therefore used in place of biosynthesis. +is_a: GO:0042403 ! thyroid hormone metabolic process + +[Term] +id: GO:0006591 +name: ornithine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis." [GOC:jl, ISBN:0192801023] +synonym: "ornithine metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006592 +name: ornithine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis." [GOC:jl, ISBN:0192801023] +synonym: "ornithine anabolism" EXACT [] +synonym: "ornithine biosynthesis" EXACT [] +synonym: "ornithine formation" EXACT [] +synonym: "ornithine synthesis" EXACT [] +is_a: GO:0006591 ! ornithine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0006593 +name: ornithine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis." [GOC:jl, ISBN:0192801023] +synonym: "ornithine breakdown" EXACT [] +synonym: "ornithine catabolism" EXACT [] +synonym: "ornithine degradation" EXACT [] +is_a: GO:0006591 ! ornithine metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0006595 +name: polyamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups." [ISBN:0198506732] +synonym: "polyamine metabolism" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process + +[Term] +id: GO:0006596 +name: polyamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups." [ISBN:0198506732] +synonym: "polyamine anabolism" EXACT [] +synonym: "polyamine biosynthesis" EXACT [] +synonym: "polyamine formation" EXACT [] +synonym: "polyamine synthesis" EXACT [] +xref: MetaCyc:POLYAMSYN-PWY +is_a: GO:0006595 ! polyamine metabolic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process + +[Term] +id: GO:0006597 +name: spermine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging." [GOC:curators] +synonym: "spermine anabolism" EXACT [] +synonym: "spermine biosynthesis" EXACT [] +synonym: "spermine formation" EXACT [] +synonym: "spermine synthesis" EXACT [] +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:0008215 ! spermine metabolic process + +[Term] +id: GO:0006598 +name: polyamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups." [ISBN:0198506732] +synonym: "polyamine breakdown" EXACT [] +synonym: "polyamine catabolism" EXACT [] +synonym: "polyamine degradation" EXACT [] +is_a: GO:0006595 ! polyamine metabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process + +[Term] +id: GO:0006599 +name: phosphagen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction." [GOC:jl, ISBN:0198506732] +synonym: "phosphagen metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process + +[Term] +id: GO:0006600 +name: creatine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle." [GOC:jl, ISBN:0192801023] +synonym: "creatine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0006601 +name: creatine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle." [GOC:mah, MetaCyc:GLYCGREAT-PWY, MetaCyc:PWY-6158] +synonym: "creatine anabolism" EXACT [] +synonym: "creatine biosynthesis" EXACT [] +synonym: "creatine formation" EXACT [] +synonym: "creatine synthesis" EXACT [] +is_a: GO:0006600 ! creatine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0006602 +name: creatinine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine." [ISBN:0198506732] +synonym: "creatinine breakdown" EXACT [] +synonym: "creatinine catabolism" EXACT [] +synonym: "creatinine degradation" EXACT [] +is_a: GO:0046449 ! creatinine metabolic process +is_a: GO:0072340 ! cellular lactam catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0006603 +name: phosphocreatine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle." [PMID:16371597] +synonym: "phosphocreatine metabolism" EXACT [] +is_a: GO:0006599 ! phosphagen metabolic process + +[Term] +id: GO:0006604 +name: phosphoarginine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates." [GOC:curators, PMID:16371597] +synonym: "phosphoarginine metabolism" EXACT [] +is_a: GO:0006599 ! phosphagen metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0006605 +name: protein targeting +namespace: biological_process +def: "The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif." [GOC:ma] +comment: Note that protein targeting encompasses the transport of the protein to the specified location, and may also include additional steps such as protein processing. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pombe +subset: goslim_yeast +synonym: "nascent polypeptide association" RELATED [] +synonym: "protein sorting along secretory pathway" NARROW [] +xref: Wikipedia:Protein_targeting +is_a: GO:0006886 ! intracellular protein transport + +[Term] +id: GO:0006606 +name: protein import into nucleus +namespace: biological_process +def: "The directed movement of a protein from the cytoplasm to the nucleus." [GOC:jl] +synonym: "establishment of protein localization to nucleus" EXACT [GOC:mah] +synonym: "protein import into cell nucleus" EXACT [] +synonym: "protein nucleus import" EXACT [] +synonym: "protein transport from cytoplasm to nucleus" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0017038 ! protein import +is_a: GO:0034504 ! protein localization to nucleus +is_a: GO:0051170 ! import into nucleus +is_a: GO:0072594 ! establishment of protein localization to organelle + +[Term] +id: GO:0006607 +name: NLS-bearing protein import into nucleus +namespace: biological_process +def: "The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope." [GOC:ai] +synonym: "NLS-bearing substrate import into cell nucleus" EXACT [] +synonym: "NLS-bearing substrate import into nucleus" EXACT [GOC:bf, GOC:jl] +synonym: "NLS-bearing substrate transport from cytoplasm to nucleus" EXACT [] +synonym: "NLS-bearing substrate-nucleus import" EXACT [] +is_a: GO:0006606 ! protein import into nucleus + +[Term] +id: GO:0006608 +name: obsolete snRNP protein import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:ai] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "snRNP protein import into cell nucleus" EXACT [] +synonym: "snRNP protein transport from cytoplasm to nucleus" EXACT [] +synonym: "snRNP protein-nucleus import" EXACT [] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0006609 +name: obsolete mRNA-binding (hnRNP) protein import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:mah] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "mRNA-binding (hnRNP) protein import into cell nucleus" EXACT [] +synonym: "mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus" EXACT [] +synonym: "mRNA-binding (hnRNP) protein-nucleus import" EXACT [] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0006610 +name: ribosomal protein import into nucleus +namespace: biological_process +def: "The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus." [GOC:ai, PMID:11809816] +comment: Ribosomal protein rpl12 uses a different import pathway, which is why it has a separate GO term. +synonym: "ribosomal protein import into cell nucleus" EXACT [] +synonym: "ribosomal protein transport from cytoplasm to nucleus" EXACT [] +synonym: "ribosomal protein-nucleus import" EXACT [] +is_a: GO:0006606 ! protein import into nucleus +property_value: term_tracker_item https://github.com/geneontology/go-annotation/issues/1700 xsd:anyURI + +[Term] +id: GO:0006611 +name: protein export from nucleus +namespace: biological_process +alt_id: GO:0097349 +def: "The directed movement of a protein from the nucleus into the cytoplasm." [GOC:jl] +synonym: "copper-induced protein export from nucleus" RELATED [GOC:al] +synonym: "protein export from cell nucleus" EXACT [] +synonym: "protein export out of nucleus" EXACT [] +synonym: "protein transport from nucleus to cytoplasm" EXACT [] +synonym: "protein-nucleus export" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0051168 ! nuclear export + +[Term] +id: GO:0006612 +name: protein targeting to membrane +namespace: biological_process +def: "The process of directing proteins towards a membrane, usually using signals contained within the protein." [GOC:curators] +synonym: "protein membrane targeting" EXACT [] +synonym: "protein-membrane targeting" EXACT [] +is_a: GO:0006605 ! protein targeting +is_a: GO:0090150 ! establishment of protein localization to membrane + +[Term] +id: GO:0006613 +name: cotranslational protein targeting to membrane +namespace: biological_process +def: "The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria." [ISBN:0716731363, PMID:10512867, PMID:16896215] +synonym: "cotranslational membrane targeting" EXACT [] +synonym: "cotranslational protein membrane targeting" EXACT [] +synonym: "cotranslational protein-membrane targeting" EXACT [] +is_a: GO:0006612 ! protein targeting to membrane + +[Term] +id: GO:0006614 +name: SRP-dependent cotranslational protein targeting to membrane +namespace: biological_process +def: "The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane." [ISBN:0716731363] +synonym: "ER translocation" BROAD [] +synonym: "SRP-dependent cotranslational membrane targeting" EXACT [] +synonym: "SRP-dependent cotranslational protein-membrane targeting" EXACT [] +is_a: GO:0006613 ! cotranslational protein targeting to membrane +is_a: GO:0045047 ! protein targeting to ER +relationship: has_part GO:0006412 ! translation + +[Term] +id: GO:0006615 +name: SRP-dependent cotranslational protein targeting to membrane, docking +namespace: biological_process +def: "The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting." [ISBN:0815316194] +synonym: "protein docking during SRP-dependent cotranslational protein targeting to membrane" EXACT [] +synonym: "SRP-dependent cotranslational membrane targeting, docking" EXACT [] +synonym: "SRP-dependent cotranslational protein-membrane targeting, docking" EXACT [] +is_a: GO:0022615 ! protein to membrane docking +relationship: part_of GO:0006614 ! SRP-dependent cotranslational protein targeting to membrane + +[Term] +id: GO:0006616 +name: SRP-dependent cotranslational protein targeting to membrane, translocation +namespace: biological_process +def: "The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen." [ISBN:0716731363] +synonym: "ER translocation" BROAD [] +synonym: "SRP-dependent cotranslational membrane targeting, translocation" EXACT [] +synonym: "SRP-dependent cotranslational protein-membrane targeting, translocation" EXACT [] +synonym: "translocation during SRP-dependent cotranslational protein targeting to membrane" EXACT [] +is_a: GO:0065002 ! intracellular protein transmembrane transport +relationship: part_of GO:0006614 ! SRP-dependent cotranslational protein targeting to membrane + +[Term] +id: GO:0006617 +name: SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition +namespace: biological_process +def: "The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting." [ISBN:0815316194] +synonym: "signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane" EXACT [] +synonym: "SRP-dependent cotranslational membrane targeting, signal sequence recognition" EXACT [] +synonym: "SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0006614 ! SRP-dependent cotranslational protein targeting to membrane + +[Term] +id: GO:0006618 +name: SRP-dependent cotranslational protein targeting to membrane, signal sequence processing +namespace: biological_process +def: "The removal of the signal peptide from a nascent protein during cotranslational membrane targeting." [ISBN:0815316194] +synonym: "signal sequence processing during SRP-dependent cotranslational protein targeting to membrane" EXACT [] +synonym: "SRP-dependent cotranslational membrane targeting, signal sequence processing" EXACT [] +synonym: "SRP-dependent cotranslational protein-membrane targeting, signal sequence processing" EXACT [] +is_a: GO:0006465 ! signal peptide processing +relationship: part_of GO:0006614 ! SRP-dependent cotranslational protein targeting to membrane + +[Term] +id: GO:0006619 +name: obsolete SRP-independent cotranslational protein-membrane targeting +namespace: biological_process +def: "OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition." [GOC:ai, PMID:11101515] +comment: This term was made obsolete because there is no evidence for the existence of this process. +synonym: "ER translocation" BROAD [] +synonym: "SRP-independent cotranslational membrane targeting" EXACT [] +synonym: "SRP-independent cotranslational protein-membrane targeting" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006620 +name: posttranslational protein targeting to endoplasmic reticulum membrane +namespace: biological_process +def: "The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane." [ISBN:0716731363] +synonym: "posttranslational endoplasmic reticulum membrane targeting" EXACT [] +synonym: "posttranslational endoplasmic reticulum protein-membrane targeting" EXACT [] +synonym: "posttranslational protein endoplasmic reticulum membrane targeting" EXACT [] +synonym: "posttranslational protein targeting to ER membrane" EXACT [] +synonym: "SRP-independent endoplasmic reticulum protein-membrane targeting" EXACT [] +is_a: GO:0006612 ! protein targeting to membrane +is_a: GO:0045047 ! protein targeting to ER + +[Term] +id: GO:0006621 +name: protein retention in ER lumen +namespace: biological_process +def: "The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER." [ISBN:0716731363, PMID:12972550] +synonym: "maintenance of protein location in ER lumen" BROAD [GOC:dph, GOC:tb] +is_a: GO:0035437 ! maintenance of protein localization in endoplasmic reticulum + +[Term] +id: GO:0006622 +name: protein targeting to lysosome +namespace: biological_process +def: "The process of directing proteins towards the lysosome using signals contained within the protein." [GOC:curators] +synonym: "protein-lysosome targeting" EXACT [] +is_a: GO:0006623 ! protein targeting to vacuole +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0061462 ! protein localization to lysosome + +[Term] +id: GO:0006623 +name: protein targeting to vacuole +namespace: biological_process +def: "The process of directing proteins towards the vacuole, usually using signals contained within the protein." [GOC:curators] +synonym: "protein vacuolar targeting" EXACT [] +synonym: "protein-vacuolar targeting" EXACT [] +synonym: "protein-vacuole targeting" EXACT [] +synonym: "vacuolar protein sorting" EXACT [GOC:vw] +is_a: GO:0006605 ! protein targeting +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0072666 ! establishment of protein localization to vacuole + +[Term] +id: GO:0006624 +name: vacuolar protein processing +namespace: biological_process +def: "Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes." [GOC:mah] +synonym: "vacuolar protein maturation" RELATED [] +synonym: "vacuolar proteolysis" RELATED [] +is_a: GO:0016485 ! protein processing +is_a: GO:0044267 ! cellular protein metabolic process +intersection_of: GO:0016485 ! protein processing +intersection_of: occurs_in GO:0005773 ! vacuole +relationship: occurs_in GO:0005773 ! vacuole + +[Term] +id: GO:0006625 +name: protein targeting to peroxisome +namespace: biological_process +def: "The process of directing proteins towards the peroxisome, usually using signals contained within the protein." [GOC:ai] +synonym: "protein-peroxisome targeting" EXACT [] +is_a: GO:0006605 ! protein targeting +is_a: GO:0043574 ! peroxisomal transport +is_a: GO:0072663 ! establishment of protein localization to peroxisome + +[Term] +id: GO:0006626 +name: protein targeting to mitochondrion +namespace: biological_process +alt_id: GO:0043681 +def: "The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein." [GOC:mcc, ISBN:0716731363] +synonym: "mitochondrial protein import" RELATED [] +synonym: "mitochondrial translocation" RELATED [] +synonym: "protein import into mitochondrion" EXACT [] +synonym: "protein targeting to mitochondria" EXACT [] +synonym: "protein-mitochondrial targeting" EXACT [] +is_a: GO:0006605 ! protein targeting +is_a: GO:0006839 ! mitochondrial transport +is_a: GO:0072655 ! establishment of protein localization to mitochondrion +relationship: part_of GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0006627 +name: protein processing involved in protein targeting to mitochondrion +namespace: biological_process +def: "The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments." [GOC:mcc, PMID:12191769] +synonym: "mitochondrial processing" BROAD [] +synonym: "mitochondrial protein processing during import" RELATED [GOC:dph, GOC:tb] +is_a: GO:0034982 ! mitochondrial protein processing +intersection_of: GO:0016485 ! protein processing +intersection_of: part_of GO:0006626 ! protein targeting to mitochondrion +relationship: part_of GO:0006626 ! protein targeting to mitochondrion + +[Term] +id: GO:0006628 +name: obsolete mitochondrial translocation +namespace: biological_process +def: "OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery." [PMID:7600576] +comment: This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation. +synonym: "mitochondrial translocation" EXACT [] +is_obsolete: true +consider: GO:0006626 + +[Term] +id: GO:0006629 +name: lipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_pombe +subset: goslim_yeast +synonym: "lipid metabolism" EXACT [] +xref: Wikipedia:Lipid_metabolism +is_a: GO:0044238 ! primary metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0006630 +name: obsolete lipid binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "lipid binding" EXACT [] +is_obsolete: true +consider: GO:0008289 + +[Term] +id: GO:0006631 +name: fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198547684] +synonym: "fatty acid metabolism" EXACT [] +xref: Wikipedia:Fatty_acid_metabolism +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0006633 +name: fatty acid biosynthetic process +namespace: biological_process +alt_id: GO:0000037 +def: "The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:mah, ISBN:0198506732] +synonym: "fatty acid anabolism" EXACT [] +synonym: "fatty acid biosynthesis" EXACT [] +synonym: "fatty acid formation" EXACT [] +synonym: "fatty acid synthesis" EXACT [] +xref: MetaCyc:FASYN-INITIAL-PWY +xref: MetaCyc:PWY-4381 +xref: MetaCyc:PWY-5156 +xref: Wikipedia:Fatty_acid_synthesis +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0006634 +name: hexadecanal biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde." [http://chemfinder.cambridgesoft.com/] +synonym: "hexadecanal anabolism" EXACT [] +synonym: "hexadecanal biosynthesis" EXACT [] +synonym: "hexadecanal formation" EXACT [] +synonym: "hexadecanal synthesis" EXACT [] +synonym: "palmitaldehyde biosynthesis" EXACT [] +synonym: "palmitaldehyde biosynthetic process" EXACT [] +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0046458 ! hexadecanal metabolic process + +[Term] +id: GO:0006635 +name: fatty acid beta-oxidation +namespace: biological_process +def: "A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, ISBN:0198506732, MetaCyc:FAO-PWY] +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0006636 +name: unsaturated fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms." [GOC:mah, MetaCyc:PWY-762, MetaCyc:PWY-782] +synonym: "fatty acid desaturation" RELATED [] +synonym: "polyunsaturated fatty acid biosynthesis" NARROW [GOC:yaf, MetaCyc:PWY-762] +synonym: "unsaturated fatty acid anabolism" EXACT [] +synonym: "unsaturated fatty acid biosynthesis" EXACT [] +synonym: "unsaturated fatty acid formation" EXACT [] +synonym: "unsaturated fatty acid synthesis" EXACT [] +xref: MetaCyc:PWY-762 +xref: MetaCyc:PWY-782 +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process + +[Term] +id: GO:0006637 +name: acyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group." [ISBN:0198506732] +synonym: "acyl-CoA metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0033875 ! ribonucleoside bisphosphate metabolic process +is_a: GO:0034032 ! purine nucleoside bisphosphate metabolic process +is_a: GO:0035383 ! thioester metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0006638 +name: neutral lipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity." [ISBN:0198547684] +synonym: "neutral lipid metabolism" EXACT [] +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0006639 +name: acylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids." [ISBN:0198506732] +synonym: "acylglycerol metabolism" EXACT [] +synonym: "glyceride metabolic process" EXACT [] +synonym: "glyceride metabolism" EXACT [] +is_a: GO:0006638 ! neutral lipid metabolic process +is_a: GO:0046486 ! glycerolipid metabolic process + +[Term] +id: GO:0006640 +name: monoacylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified." [ISBN:0198506732] +synonym: "monoacylglycerol anabolism" EXACT [] +synonym: "monoacylglycerol biosynthesis" EXACT [] +synonym: "monoacylglycerol formation" EXACT [] +synonym: "monoacylglycerol synthesis" EXACT [] +synonym: "monoglyceride biosynthesis" EXACT [] +synonym: "monoglyceride biosynthetic process" EXACT [] +is_a: GO:0046462 ! monoacylglycerol metabolic process +is_a: GO:0046463 ! acylglycerol biosynthetic process + +[Term] +id: GO:0006641 +name: triglyceride metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins." [ISBN:0198506732] +synonym: "triacylglycerol metabolic process" EXACT [] +synonym: "triacylglycerol metabolism" EXACT [] +synonym: "triglyceride metabolism" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process + +[Term] +id: GO:0006642 +name: triglyceride mobilization +namespace: biological_process +def: "The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism." [GOC:mah, PMID:11943743, PMID:15713625] +synonym: "triacylglycerol mobilization" EXACT [] +is_a: GO:0006641 ! triglyceride metabolic process + +[Term] +id: GO:0006643 +name: membrane lipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] +synonym: "membrane lipid metabolism" EXACT [] +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0006644 +name: phospholipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester." [ISBN:0198506732] +synonym: "phospholipid metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0006646 +name: phosphatidylethanolamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732] +synonym: "phosphatidylethanolamine anabolism" EXACT [] +synonym: "phosphatidylethanolamine biosynthesis" EXACT [] +synonym: "phosphatidylethanolamine formation" EXACT [] +synonym: "phosphatidylethanolamine synthesis" EXACT [] +is_a: GO:0046337 ! phosphatidylethanolamine metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process + +[Term] +id: GO:0006647 +name: phosphatidyl-N-monomethylethanolamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group." [GOC:ai] +synonym: "phosphatidyl-N-monomethylethanolamine anabolism" EXACT [] +synonym: "phosphatidyl-N-monomethylethanolamine biosynthesis" EXACT [] +synonym: "phosphatidyl-N-monomethylethanolamine formation" EXACT [] +synonym: "phosphatidyl-N-monomethylethanolamine synthesis" EXACT [] +synonym: "PMME biosynthesis" EXACT [] +synonym: "PMME biosynthetic process" EXACT [] +is_a: GO:0006646 ! phosphatidylethanolamine biosynthetic process +is_a: GO:0046468 ! phosphatidyl-N-monomethylethanolamine metabolic process + +[Term] +id: GO:0006648 +name: dihydrosphingosine-1-P pathway +namespace: biological_process +def: "A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase." [GOC:mah, PMID:15643073] +is_a: GO:0006646 ! phosphatidylethanolamine biosynthetic process + +[Term] +id: GO:0006649 +name: phospholipid transfer to membrane +namespace: biological_process +def: "The transfer of a phospholipid from its site of synthesis to the plasma membrane." [GOC:go_curators] +is_a: GO:0015914 ! phospholipid transport +relationship: part_of GO:0061024 ! membrane organization + +[Term] +id: GO:0006650 +name: glycerophospholipid metabolic process +namespace: biological_process +alt_id: GO:0006652 +def: "The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue." [ISBN:0198506732] +synonym: "alpha-glycerophosphate pathway" RELATED [] +synonym: "glycerophospholipid metabolism" EXACT [] +synonym: "phosphoglyceride metabolic process" EXACT [] +synonym: "phosphoglyceride metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0046486 ! glycerolipid metabolic process + +[Term] +id: GO:0006651 +name: diacylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group." [GOC:curators] +synonym: "diacylglycerol anabolism" EXACT [] +synonym: "diacylglycerol biosynthesis" EXACT [] +synonym: "diacylglycerol formation" EXACT [] +synonym: "diacylglycerol synthesis" EXACT [] +synonym: "diglyceride biosynthesis" EXACT [] +is_a: GO:0046339 ! diacylglycerol metabolic process +is_a: GO:0046463 ! acylglycerol biosynthetic process + +[Term] +id: GO:0006653 +name: 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin." [ISBN:0198506732] +synonym: "1,2-diacyl-sn-glycero-3-phosphocholine metabolism" EXACT [GOC:mah] +synonym: "lecithin metabolic process" BROAD [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046470 ! phosphatidylcholine metabolic process + +[Term] +id: GO:0006654 +name: phosphatidic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids." [ISBN:0198506732] +synonym: "phosphatidic acid anabolism" EXACT [] +synonym: "phosphatidic acid biosynthesis" EXACT [] +synonym: "phosphatidic acid formation" EXACT [] +synonym: "phosphatidic acid synthesis" EXACT [] +is_a: GO:0046473 ! phosphatidic acid metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process + +[Term] +id: GO:0006655 +name: phosphatidylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol." [ISBN:0198506732] +synonym: "phosphatidylglycerol anabolism" EXACT [] +synonym: "phosphatidylglycerol biosynthesis" EXACT [] +synonym: "phosphatidylglycerol formation" EXACT [] +synonym: "phosphatidylglycerol synthesis" EXACT [] +is_a: GO:0046471 ! phosphatidylglycerol metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process + +[Term] +id: GO:0006656 +name: phosphatidylcholine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [ISBN:0198506732] +synonym: "phosphatidylcholine anabolism" EXACT [] +synonym: "phosphatidylcholine biosynthesis" EXACT [] +synonym: "phosphatidylcholine formation" EXACT [] +synonym: "phosphatidylcholine synthesis" EXACT [] +is_a: GO:0046470 ! phosphatidylcholine metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0006657 +name: CDP-choline pathway +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine." [ISBN:0471331309, MetaCyc:PWY3O-450] +synonym: "Kennedy pathway" EXACT [MetaCyc:PWY3O-450] +synonym: "phosphatidylcholine biosynthesis from choline" EXACT [GOC:mah, MetaCyc:PWY3O-450] +xref: MetaCyc:PWY3O-450 +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process + +[Term] +id: GO:0006658 +name: phosphatidylserine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes." [ISBN:0198506732] +synonym: "phosphatidylserine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0006659 +name: phosphatidylserine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine." [ISBN:0198506732] +synonym: "phosphatidylserine anabolism" EXACT [] +synonym: "phosphatidylserine biosynthesis" EXACT [] +synonym: "phosphatidylserine formation" EXACT [] +synonym: "phosphatidylserine synthesis" EXACT [] +is_a: GO:0006658 ! phosphatidylserine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process + +[Term] +id: GO:0006660 +name: phosphatidylserine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine." [ISBN:0198506732] +synonym: "phosphatidylserine breakdown" EXACT [] +synonym: "phosphatidylserine catabolism" EXACT [] +synonym: "phosphatidylserine degradation" EXACT [] +is_a: GO:0006658 ! phosphatidylserine metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process + +[Term] +id: GO:0006661 +name: phosphatidylinositol biosynthetic process +namespace: biological_process +alt_id: GO:0046489 +def: "The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [ISBN:0198506732] +synonym: "phosphatidylinositol anabolism" EXACT [] +synonym: "phosphatidylinositol biosynthesis" EXACT [] +synonym: "phosphatidylinositol formation" EXACT [] +synonym: "phosphatidylinositol synthesis" EXACT [] +synonym: "phosphoinositide biosynthesis" EXACT [] +synonym: "phosphoinositide biosynthetic process" EXACT [] +synonym: "PtdIns biosynthesis" EXACT [] +synonym: "PtdIns biosynthetic process" EXACT [] +is_a: GO:0046474 ! glycerophospholipid biosynthetic process +is_a: GO:0046488 ! phosphatidylinositol metabolic process + +[Term] +id: GO:0006662 +name: glycerol ether metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol." [GOC:ai, ISBN:0198506732] +subset: goslim_pir +synonym: "glycerol ether metabolism" EXACT [] +is_a: GO:0018904 ! ether metabolic process + +[Term] +id: GO:0006663 +name: platelet activating factor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli." [ISBN:0198547684] +synonym: "PAF biosynthesis" EXACT [] +synonym: "PAF biosynthetic process" EXACT [] +synonym: "platelet activating factor anabolism" EXACT [] +synonym: "platelet activating factor biosynthesis" EXACT [] +synonym: "platelet activating factor formation" EXACT [] +synonym: "platelet activating factor synthesis" EXACT [] +is_a: GO:0046469 ! platelet activating factor metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0006664 +name: glycolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent." [ISBN:0198547684] +synonym: "glycolipid metabolism" EXACT [] +is_a: GO:0006643 ! membrane lipid metabolic process +is_a: GO:1903509 ! liposaccharide metabolic process + +[Term] +id: GO:0006665 +name: sphingolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] +synonym: "sphingolipid metabolism" EXACT [] +is_a: GO:0006643 ! membrane lipid metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006666 +name: 3-keto-sphinganine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine." [GOC:ai] +synonym: "3-keto-dihydrosphingosine metabolic process" EXACT [] +synonym: "3-keto-dihydrosphingosine metabolism" EXACT [] +synonym: "3-keto-sphinganine metabolism" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0006667 +name: sphinganine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol." [PMID:29165427] +synonym: "dihydrosphingosine metabolic process" EXACT [] +synonym: "dihydrosphingosine metabolism" EXACT [] +synonym: "sphinganine metabolism" EXACT [] +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0006668 +name: sphinganine-1-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol." [GOC:ai] +synonym: "dihydrosphingosine-1-phosphate metabolic process" EXACT [] +synonym: "dihydrosphingosine-1-phosphate metabolism" EXACT [] +synonym: "sphinganine-1-phosphate metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006665 ! sphingolipid metabolic process + +[Term] +id: GO:0006669 +name: sphinganine-1-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol." [GOC:ai] +synonym: "dihydrosphingosine-1-phosphate biosynthesis" EXACT [] +synonym: "dihydrosphingosine-1-phosphate biosynthetic process" EXACT [] +synonym: "sphinganine-1-phosphate anabolism" EXACT [] +synonym: "sphinganine-1-phosphate biosynthesis" EXACT [] +synonym: "sphinganine-1-phosphate formation" EXACT [] +synonym: "sphinganine-1-phosphate synthesis" EXACT [] +is_a: GO:0006668 ! sphinganine-1-phosphate metabolic process +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0030148 ! sphingolipid biosynthetic process + +[Term] +id: GO:0006670 +name: sphingosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues." [GOC:ma, ISBN:0198506732] +synonym: "(4E)-sphing-4-enine metabolic process" EXACT [] +synonym: "(4E)-sphing-4-enine metabolism" EXACT [] +synonym: "sphing-4-enine metabolic process" EXACT [] +synonym: "sphing-4-enine metabolism" EXACT [] +synonym: "sphingosine metabolism" EXACT [] +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0006671 +name: phytosphingosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids." [ISBN:0198506732] +synonym: "phytosphingosine metabolism" EXACT [] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0006672 +name: ceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ceramides, any N-acylated sphingoid." [ISBN:0198547684] +synonym: "ceramide metabolism" EXACT [] +is_a: GO:0006665 ! sphingolipid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0006673 +name: inositol phosphoceramide metabolic process +namespace: biological_process +alt_id: GO:0006674 +def: "The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group." [PMID:19726565] +synonym: "inositol phosphorylceramide metabolic process" EXACT [] +synonym: "inositol phosphorylceramide metabolism" EXACT [] +synonym: "inositolphosphoceramide metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006665 ! sphingolipid metabolic process + +[Term] +id: GO:0006675 +name: mannosyl-inositol phosphorylceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai, MetaCyc:MIPC] +synonym: "mannose inositol phosphoceramide metabolic process" EXACT [] +synonym: "mannose inositol phosphoceramide metabolism" EXACT [] +synonym: "mannose-inositol-P-ceramide (MIPC) metabolic process" EXACT [] +synonym: "mannose-inositol-P-ceramide (MIPC) metabolism" EXACT [] +synonym: "mannosyl-inositol-phosphorylceramide metabolism" EXACT [] +synonym: "MIPC metabolic process" EXACT [] +synonym: "MIPC metabolism" EXACT [] +is_a: GO:0006673 ! inositol phosphoceramide metabolic process +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0006676 +name: mannosyl diphosphorylinositol ceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai] +synonym: "M(IP)2C metabolic process" EXACT [] +synonym: "M(IP)2C metabolism" EXACT [] +synonym: "mannosyl diphosphorylinositol ceramide metabolism" EXACT [] +is_a: GO:0006505 ! GPI anchor metabolic process +is_a: GO:0006673 ! inositol phosphoceramide metabolic process + +[Term] +id: GO:0006677 +name: glycosylceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group." [GOC:ai, ISBN:0198506732] +synonym: "glycosylceramide metabolism" EXACT [] +is_a: GO:0006672 ! ceramide metabolic process +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0006678 +name: glucosylceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative." [ISBN:0198506732] +synonym: "glucosylceramide metabolism" EXACT [] +is_a: GO:0006677 ! glycosylceramide metabolic process + +[Term] +id: GO:0006679 +name: glucosylceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group." [GOC:ai] +synonym: "glucosylceramide anabolism" EXACT [] +synonym: "glucosylceramide biosynthesis" EXACT [] +synonym: "glucosylceramide formation" EXACT [] +synonym: "glucosylceramide synthesis" EXACT [] +is_a: GO:0006678 ! glucosylceramide metabolic process +is_a: GO:0046476 ! glycosylceramide biosynthetic process + +[Term] +id: GO:0006680 +name: glucosylceramide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group." [GOC:ai] +synonym: "glucosylceramide breakdown" EXACT [] +synonym: "glucosylceramide catabolism" EXACT [] +synonym: "glucosylceramide degradation" EXACT [] +is_a: GO:0006678 ! glucosylceramide metabolic process +is_a: GO:0046477 ! glycosylceramide catabolic process + +[Term] +id: GO:0006681 +name: galactosylceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group." [GOC:ai] +synonym: "galactosylceramide metabolism" EXACT [] +is_a: GO:0006677 ! glycosylceramide metabolic process +is_a: GO:0019374 ! galactolipid metabolic process + +[Term] +id: GO:0006682 +name: galactosylceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group." [GOC:ai] +synonym: "galactosylceramide anabolism" EXACT [] +synonym: "galactosylceramide biosynthesis" EXACT [] +synonym: "galactosylceramide formation" EXACT [] +synonym: "galactosylceramide synthesis" EXACT [] +is_a: GO:0006681 ! galactosylceramide metabolic process +is_a: GO:0019375 ! galactolipid biosynthetic process +is_a: GO:0046476 ! glycosylceramide biosynthetic process + +[Term] +id: GO:0006683 +name: galactosylceramide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group." [GOC:ai] +synonym: "galactosylceramide breakdown" EXACT [] +synonym: "galactosylceramide catabolism" EXACT [] +synonym: "galactosylceramide degradation" EXACT [] +is_a: GO:0006681 ! galactosylceramide metabolic process +is_a: GO:0019376 ! galactolipid catabolic process +is_a: GO:0046477 ! glycosylceramide catabolic process + +[Term] +id: GO:0006684 +name: sphingomyelin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine." [ISBN:0198506732] +synonym: "sphingomyelin metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006665 ! sphingolipid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0006685 +name: sphingomyelin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine." [ISBN:0198506732] +synonym: "sphingomyelin breakdown" EXACT [] +synonym: "sphingomyelin catabolism" EXACT [] +synonym: "sphingomyelin degradation" EXACT [] +is_a: GO:0006684 ! sphingomyelin metabolic process +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0030149 ! sphingolipid catabolic process + +[Term] +id: GO:0006686 +name: sphingomyelin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine." [ISBN:0198506732] +synonym: "sphingomyelin anabolism" EXACT [] +synonym: "sphingomyelin biosynthesis" EXACT [] +synonym: "sphingomyelin formation" EXACT [] +synonym: "sphingomyelin synthesis" EXACT [] +is_a: GO:0006684 ! sphingomyelin metabolic process +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0030148 ! sphingolipid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process + +[Term] +id: GO:0006687 +name: glycosphingolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide." [ISBN:0198547684] +synonym: "glycosphingolipid metabolism" EXACT [] +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0006665 ! sphingolipid metabolic process + +[Term] +id: GO:0006688 +name: glycosphingolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide." [GOC:go_curators] +synonym: "glycosphingolipid anabolism" EXACT [] +synonym: "glycosphingolipid biosynthesis" EXACT [] +synonym: "glycosphingolipid formation" EXACT [] +synonym: "glycosphingolipid synthesis" EXACT [] +is_a: GO:0006687 ! glycosphingolipid metabolic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0030148 ! sphingolipid biosynthetic process + +[Term] +id: GO:0006689 +name: ganglioside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues." [ISBN:0198547684] +synonym: "ganglioside breakdown" EXACT [] +synonym: "ganglioside catabolism" EXACT [] +synonym: "ganglioside degradation" EXACT [] +is_a: GO:0001573 ! ganglioside metabolic process +is_a: GO:0046479 ! glycosphingolipid catabolic process +is_a: GO:0046514 ! ceramide catabolic process + +[Term] +id: GO:0006690 +name: icosanoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids." [GOC:ma] +synonym: "eicosanoid metabolic process" EXACT [] +synonym: "eicosanoid metabolism" EXACT [] +synonym: "icosanoid metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:1901568 ! fatty acid derivative metabolic process + +[Term] +id: GO:0006691 +name: leukotriene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid." [GOC:ma] +synonym: "leukotriene metabolism" EXACT [] +is_a: GO:0006690 ! icosanoid metabolic process +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0006692 +name: prostanoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure." [ISBN:0198506732] +synonym: "prostanoid metabolism" EXACT [] +is_a: GO:0006690 ! icosanoid metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process + +[Term] +id: GO:0006693 +name: prostaglandin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities." [ISBN:0198506732] +synonym: "prostaglandin metabolism" EXACT [] +is_a: GO:0006692 ! prostanoid metabolic process + +[Term] +id: GO:0006694 +name: steroid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators] +synonym: "steroid anabolism" EXACT [] +synonym: "steroid biosynthesis" EXACT [] +synonym: "steroid formation" EXACT [] +synonym: "steroid synthesis" EXACT [] +synonym: "steroidogenesis" EXACT [] +xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0006695 +name: cholesterol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:ai] +synonym: "cholesterol anabolism" EXACT [] +synonym: "cholesterol biosynthesis" EXACT [] +synonym: "cholesterol formation" EXACT [] +synonym: "cholesterol synthesis" EXACT [] +is_a: GO:0008203 ! cholesterol metabolic process +is_a: GO:0016126 ! sterol biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0006696 +name: ergosterol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds." [ISBN:0198506732] +synonym: "ergosterol anabolism" EXACT [] +synonym: "ergosterol biosynthesis" EXACT [] +synonym: "ergosterol formation" EXACT [] +synonym: "ergosterol synthesis" EXACT [] +is_a: GO:0008204 ! ergosterol metabolic process +is_a: GO:0016126 ! sterol biosynthetic process +is_a: GO:0016129 ! phytosteroid biosynthetic process +is_a: GO:0044108 ! cellular alcohol biosynthetic process +is_a: GO:0097384 ! cellular lipid biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0006697 +name: ecdysone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects." [ISBN:0198506732] +synonym: "ecdysone anabolism" EXACT [] +synonym: "ecdysone biosynthesis" EXACT [] +synonym: "ecdysone formation" EXACT [] +synonym: "ecdysone synthesis" EXACT [] +is_a: GO:0008205 ! ecdysone metabolic process +is_a: GO:0016126 ! sterol biosynthetic process +is_a: GO:0045456 ! ecdysteroid biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0006698 +name: obsolete ecdysone modification +namespace: biological_process +def: "OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties." [GOC:jl] +comment: This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC:1.14.99.22) and so is a function rather than a process. +synonym: "ecdysone modification" EXACT [] +is_obsolete: true +replaced_by: GO:0004501 + +[Term] +id: GO:0006699 +name: bile acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] +synonym: "bile acid anabolism" EXACT [] +synonym: "bile acid biosynthesis" EXACT [] +synonym: "bile acid formation" EXACT [] +synonym: "bile acid synthesis" EXACT [] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0008206 ! bile acid metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0006700 +name: C21-steroid hormone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones." [GOC:ai] +synonym: "C21-steroid hormone anabolism" EXACT [] +synonym: "C21-steroid hormone biosynthesis" EXACT [] +synonym: "C21-steroid hormone formation" EXACT [] +synonym: "C21-steroid hormone synthesis" EXACT [] +is_a: GO:0008207 ! C21-steroid hormone metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0006701 +name: progesterone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants." [GOC:jl, http://www.cogsci.princeton.edu/] +synonym: "progesterone anabolism" EXACT [] +synonym: "progesterone biosynthesis" EXACT [] +synonym: "progesterone formation" EXACT [] +synonym: "progesterone synthesis" EXACT [] +is_a: GO:0006700 ! C21-steroid hormone biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0042448 ! progesterone metabolic process + +[Term] +id: GO:0006702 +name: androgen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics." [ISBN:0198506732] +synonym: "androgen anabolism" EXACT [] +synonym: "androgen biosynthesis" EXACT [] +synonym: "androgen formation" EXACT [] +synonym: "androgen synthesis" EXACT [] +is_a: GO:0008209 ! androgen metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0006703 +name: estrogen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants." [ISBN:0198506732] +synonym: "estrogen anabolism" EXACT [] +synonym: "estrogen biosynthesis" EXACT [] +synonym: "estrogen formation" EXACT [] +synonym: "estrogen synthesis" EXACT [] +synonym: "oestrogen biosynthesis" EXACT [] +synonym: "oestrogen biosynthetic process" EXACT [] +is_a: GO:0008210 ! estrogen metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0006704 +name: glucocorticoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol." [ISBN:0198506732] +synonym: "glucocorticoid anabolism" EXACT [] +synonym: "glucocorticoid biosynthesis" EXACT [] +synonym: "glucocorticoid formation" EXACT [] +synonym: "glucocorticoid synthesis" EXACT [] +is_a: GO:0008211 ! glucocorticoid metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0006705 +name: mineralocorticoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol." [ISBN:0198506732] +synonym: "mineralocorticoid anabolism" EXACT [] +synonym: "mineralocorticoid biosynthesis" EXACT [] +synonym: "mineralocorticoid formation" EXACT [] +synonym: "mineralocorticoid synthesis" EXACT [] +is_a: GO:0008212 ! mineralocorticoid metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0006706 +name: steroid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators] +synonym: "steroid breakdown" EXACT [] +synonym: "steroid catabolism" EXACT [] +synonym: "steroid degradation" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0016042 ! lipid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0006707 +name: cholesterol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:ai] +synonym: "cholesterol breakdown" EXACT [] +synonym: "cholesterol catabolism" EXACT [] +synonym: "cholesterol degradation" EXACT [] +is_a: GO:0008203 ! cholesterol metabolic process +is_a: GO:0016127 ! sterol catabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0006708 +name: ecdysone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects." [ISBN:0198506732] +synonym: "ecdysone breakdown" EXACT [] +synonym: "ecdysone catabolism" EXACT [] +synonym: "ecdysone degradation" EXACT [] +is_a: GO:0008205 ! ecdysone metabolic process +is_a: GO:0016127 ! sterol catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0046344 ! ecdysteroid catabolic process + +[Term] +id: GO:0006709 +name: progesterone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants." [GOC:jl, http://www.cogsci.princeton.edu/] +synonym: "progesterone breakdown" EXACT [] +synonym: "progesterone catabolism" EXACT [] +synonym: "progesterone degradation" EXACT [] +is_a: GO:0008208 ! C21-steroid hormone catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042448 ! progesterone metabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0006710 +name: androgen catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics." [ISBN:0198506732] +synonym: "androgen breakdown" EXACT [] +synonym: "androgen catabolism" EXACT [] +synonym: "androgen degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0008209 ! androgen metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0006711 +name: estrogen catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants." [ISBN:0198506732] +synonym: "estrogen breakdown" EXACT [] +synonym: "estrogen catabolism" EXACT [] +synonym: "estrogen degradation" EXACT [] +synonym: "oestrogen catabolic process" EXACT [] +synonym: "oestrogen catabolism" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0008210 ! estrogen metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0006712 +name: mineralocorticoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol." [ISBN:0198506732] +synonym: "mineralocorticoid breakdown" EXACT [] +synonym: "mineralocorticoid catabolism" EXACT [] +synonym: "mineralocorticoid degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0008212 ! mineralocorticoid metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0006713 +name: glucocorticoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol." [ISBN:0198506732] +synonym: "glucocorticoid breakdown" EXACT [] +synonym: "glucocorticoid catabolism" EXACT [] +synonym: "glucocorticoid degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0008211 ! glucocorticoid metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0006714 +name: sesquiterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units." [ISBN:0198547684] +synonym: "sesquiterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0006715 +name: farnesol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol." [ISBN:0198547684] +synonym: "farnesol anabolism" EXACT [] +synonym: "farnesol biosynthesis" EXACT [] +synonym: "farnesol formation" EXACT [] +synonym: "farnesol synthesis" EXACT [] +is_a: GO:0016094 ! polyprenol biosynthetic process +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0016487 ! farnesol metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process + +[Term] +id: GO:0006716 +name: juvenile hormone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] +synonym: "juvenile hormone metabolism" EXACT [] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0006717 +name: obsolete juvenile hormone binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "juvenile hormone binding" EXACT [] +is_obsolete: true +consider: GO:0005500 + +[Term] +id: GO:0006718 +name: juvenile hormone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] +synonym: "juvenile hormone anabolism" EXACT [] +synonym: "juvenile hormone biosynthesis" EXACT [] +synonym: "juvenile hormone formation" EXACT [] +synonym: "juvenile hormone synthesis" EXACT [] +is_a: GO:0006716 ! juvenile hormone metabolic process +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process + +[Term] +id: GO:0006719 +name: juvenile hormone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] +synonym: "juvenile hormone breakdown" EXACT [] +synonym: "juvenile hormone catabolism" EXACT [] +synonym: "juvenile hormone degradation" EXACT [] +is_a: GO:0006716 ! juvenile hormone metabolic process +is_a: GO:0016107 ! sesquiterpenoid catabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0006720 +name: isoprenoid metabolic process +namespace: biological_process +alt_id: GO:0016096 +def: "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198547684] +synonym: "isoprenoid metabolism" EXACT [] +synonym: "polyisoprenoid metabolic process" NARROW [] +synonym: "polyisoprenoid metabolism" NARROW [] +synonym: "polyterpene metabolic process" NARROW [] +synonym: "polyterpene metabolism" NARROW [] +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0006721 +name: terpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups." [ISBN:0198506732] +synonym: "terpenoid metabolism" EXACT [] +is_a: GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0006722 +name: triterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units." [ISBN:0198547684] +synonym: "triterpene metabolic process" NARROW [] +synonym: "triterpene metabolism" NARROW [] +synonym: "triterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0006723 +name: cuticle hydrocarbon biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss." [GOC:ai] +synonym: "cuticle hydrocarbon anabolism" EXACT [] +synonym: "cuticle hydrocarbon biosynthesis" EXACT [] +synonym: "cuticle hydrocarbon formation" EXACT [] +synonym: "cuticle hydrocarbon synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +relationship: part_of GO:0042335 ! cuticle development + +[Term] +id: GO:0006725 +name: cellular aromatic compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] +subset: goslim_pir +synonym: "aromatic compound metabolism" EXACT [] +synonym: "aromatic hydrocarbon metabolic process" NARROW [] +synonym: "aromatic hydrocarbon metabolism" NARROW [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0006726 +name: eye pigment biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye." [GOC:ai] +synonym: "eye pigment anabolism" EXACT [] +synonym: "eye pigment biosynthesis" EXACT [] +synonym: "eye pigment formation" EXACT [] +synonym: "eye pigment synthesis" EXACT [] +is_a: GO:0042441 ! eye pigment metabolic process +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0006727 +name: ommochrome biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye." [ISBN:0198506732] +synonym: "ommochrome anabolism" EXACT [] +synonym: "ommochrome biosynthesis" EXACT [] +synonym: "ommochrome formation" EXACT [] +synonym: "ommochrome synthesis" EXACT [] +is_a: GO:0006726 ! eye pigment biosynthetic process +is_a: GO:0008055 ! ocellus pigment biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0046152 ! ommochrome metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0006728 +name: pteridine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group." [ISBN:0198506732] +synonym: "pteridine anabolism" EXACT [] +synonym: "pteridine biosynthesis" EXACT [] +synonym: "pteridine formation" EXACT [] +synonym: "pteridine synthesis" EXACT [] +synonym: "pterin biosynthesis" NARROW [] +synonym: "pterin biosynthetic process" NARROW [] +is_a: GO:0019889 ! pteridine metabolic process +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0006729 +name: tetrahydrobiopterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine." [ISBN:0198506732] +synonym: "5,6,7,8-tetrahydrobiopterin biosynthetic process" EXACT [] +synonym: "tetrahydrobiopterin anabolism" EXACT [] +synonym: "tetrahydrobiopterin biosynthesis" EXACT [] +synonym: "tetrahydrobiopterin formation" EXACT [] +synonym: "tetrahydrobiopterin synthesis" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0046146 ! tetrahydrobiopterin metabolic process + +[Term] +id: GO:0006730 +name: one-carbon metabolic process +namespace: biological_process +alt_id: GO:0019753 +alt_id: GO:0019754 +def: "The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states." [GOC:hjd, GOC:mah, GOC:pde] +subset: goslim_pir +synonym: "one carbon metabolic process" EXACT [GOC:mah] +synonym: "one carbon metabolism" EXACT [GOC:mah] +synonym: "one-carbon metabolism" EXACT [GOC:mah] +synonym: "one-carbon transfer metabolic process" EXACT [GOC:mah] +synonym: "one-carbon transfer metabolism" EXACT [GOC:mah] +xref: UM-BBD_pathwayID:C1cyc +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0006731 +name: obsolete coenzyme and prosthetic group metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "coenzyme and prosthetic group metabolic process" EXACT [] +is_obsolete: true +consider: GO:0006732 +consider: GO:0051189 + +[Term] +id: GO:0006732 +name: coenzyme metabolic process +namespace: biological_process +alt_id: GO:0006752 +def: "The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [ISBN:0198506732] +synonym: "coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "coenzyme and prosthetic group metabolism" BROAD [] +synonym: "coenzyme metabolism" EXACT [] +synonym: "group transfer coenzyme metabolic process" NARROW [] +synonym: "group transfer coenzyme metabolism" NARROW [] +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0006733 +name: oxidoreduction coenzyme metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed." [GOC:mah] +synonym: "oxidoreduction coenzyme metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process + +[Term] +id: GO:0006734 +name: NADH metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid." [GOC:jl, ISBN:0618254153] +synonym: "NAD (reduced) metabolic process" EXACT [] +synonym: "NAD (reduced) metabolism" EXACT [] +synonym: "NADH metabolism" EXACT [] +synonym: "reduced NAD metabolic process" EXACT [] +synonym: "reduced NAD metabolism" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide metabolic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0006735 +name: NADH regeneration +namespace: biological_process +def: "A metabolic process that generates a pool of NADH by the reduction of NAD+." [GOC:mah] +synonym: "NAD (reduced) regeneration" EXACT [] +synonym: "reduced NAD regeneration" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide regeneration" EXACT [] +is_a: GO:0006734 ! NADH metabolic process +is_a: GO:0019674 ! NAD metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006738 +name: nicotinamide riboside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide." [ISBN:0198506732] +synonym: "N-ribosylnicotinamide catabolic process" EXACT [] +synonym: "nicotinamide riboside breakdown" EXACT [] +synonym: "nicotinamide riboside catabolism" EXACT [] +synonym: "nicotinamide riboside degradation" EXACT [] +is_a: GO:0046495 ! nicotinamide riboside metabolic process +is_a: GO:0070638 ! pyridine nucleoside catabolic process + +[Term] +id: GO:0006739 +name: NADP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH." [GOC:mah] +synonym: "NAD phosphorylation and dephosphorylation" RELATED [] +synonym: "NADP (oxidized) metabolic process" EXACT [] +synonym: "NADP (oxidized) metabolism" EXACT [] +synonym: "NADP (reduced) metabolic process" EXACT [] +synonym: "NADP (reduced) metabolism" EXACT [] +synonym: "NADP metabolism" EXACT [] +synonym: "NADPH metabolic process" EXACT [] +synonym: "NADPH metabolism" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate metabolism" EXACT [] +synonym: "oxidized NADP metabolic process" EXACT [] +synonym: "oxidized NADP metabolism" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate metabolism" EXACT [] +synonym: "reduced NADP metabolic process" EXACT [] +synonym: "reduced NADP metabolism" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0006740 +name: NADPH regeneration +namespace: biological_process +def: "A metabolic process that generates a pool of NADPH by the reduction of NADP+." [GOC:mah] +synonym: "NADP (reduced) regeneration" EXACT [] +synonym: "reduced NADP regeneration" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate regeneration" EXACT [] +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0006739 ! NADP metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0006741 +name: NADP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH." [GOC:mah] +synonym: "NADP (oxidized) biosynthesis" EXACT [] +synonym: "NADP (oxidized) biosynthetic process" EXACT [] +synonym: "NADP (reduced) biosynthesis" EXACT [] +synonym: "NADP (reduced) biosynthetic process" EXACT [] +synonym: "NADP anabolism" EXACT [] +synonym: "NADP biosynthesis" EXACT [] +synonym: "NADP formation" EXACT [] +synonym: "NADP synthesis" EXACT [] +synonym: "NADPH biosynthesis" EXACT [] +synonym: "NADPH biosynthetic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate biosynthesis" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate biosynthetic process" EXACT [] +synonym: "oxidized NADP biosynthesis" EXACT [] +synonym: "oxidized NADP biosynthetic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate biosynthesis" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate biosynthetic process" EXACT [] +synonym: "reduced NADP biosynthesis" EXACT [] +synonym: "reduced NADP biosynthetic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate biosynthesis" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate biosynthetic process" EXACT [] +is_a: GO:0006739 ! NADP metabolic process +is_a: GO:0019359 ! nicotinamide nucleotide biosynthetic process + +[Term] +id: GO:0006742 +name: NADP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH." [GOC:mah] +synonym: "NADP (oxidized) catabolic process" EXACT [] +synonym: "NADP (oxidized) catabolism" EXACT [] +synonym: "NADP (reduced) catabolic process" EXACT [] +synonym: "NADP (reduced) catabolism" EXACT [] +synonym: "NADP breakdown" EXACT [] +synonym: "NADP catabolism" EXACT [] +synonym: "NADP degradation" EXACT [] +synonym: "NADPH catabolic process" EXACT [] +synonym: "NADPH catabolism" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate catabolic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphate catabolism" EXACT [] +synonym: "oxidized NADP catabolic process" EXACT [] +synonym: "oxidized NADP catabolism" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate catabolic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate catabolism" EXACT [] +synonym: "reduced NADP catabolic process" EXACT [] +synonym: "reduced NADP catabolism" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate catabolic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide phosphate catabolism" EXACT [] +is_a: GO:0006739 ! NADP metabolic process +is_a: GO:0019364 ! pyridine nucleotide catabolic process +is_a: GO:0046496 ! nicotinamide nucleotide metabolic process + +[Term] +id: GO:0006743 +name: ubiquinone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme." [GOC:mah] +synonym: "coenzyme Q metabolic process" EXACT [] +synonym: "coenzyme Q metabolism" EXACT [] +synonym: "ubiquinone metabolism" EXACT [] +is_a: GO:0006733 ! oxidoreduction coenzyme metabolic process +is_a: GO:1901661 ! quinone metabolic process + +[Term] +id: GO:0006744 +name: ubiquinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme." [GOC:mah] +synonym: "coenzyme Q biosynthesis" EXACT [] +synonym: "coenzyme Q biosynthetic process" EXACT [] +synonym: "coenzyme Q10 biosynthesis" NARROW [] +synonym: "coenzyme Q10 biosynthetic process" NARROW [] +synonym: "coenzyme Q6 biosynthesis" NARROW [] +synonym: "coenzyme Q6 biosynthetic process" NARROW [] +synonym: "coenzyme Q8 biosynthesis" NARROW [] +synonym: "coenzyme Q8 biosynthetic process" NARROW [] +synonym: "coenzyme Q9 biosynthesis" NARROW [] +synonym: "coenzyme Q9 biosynthetic process" NARROW [] +synonym: "ubiquinone anabolism" EXACT [] +synonym: "ubiquinone biosynthesis" EXACT [] +synonym: "ubiquinone formation" EXACT [] +synonym: "ubiquinone synthesis" EXACT [] +xref: MetaCyc:UBISYN-PWY +is_a: GO:0006743 ! ubiquinone metabolic process +is_a: GO:1901663 ! quinone biosynthetic process + +[Term] +id: GO:0006746 +name: FADH2 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide." [GOC:ai] +synonym: "FADH2 metabolism" EXACT [] +synonym: "reduced flavin adenine dinucleotide metabolic process" EXACT [GOC:mah] +is_a: GO:0006733 ! oxidoreduction coenzyme metabolic process +is_a: GO:0072387 ! flavin adenine dinucleotide metabolic process + +[Term] +id: GO:0006747 +name: FAD biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide." [GOC:ai, PMID:20822113] +synonym: "FAD anabolism" EXACT [] +synonym: "FAD biosynthesis" EXACT [] +synonym: "FAD formation" EXACT [] +synonym: "FAD synthesis" EXACT [] +synonym: "oxidized flavin adenine dinucleotide biosynthesis" EXACT [] +synonym: "oxidized flavin adenine dinucleotide biosynthetic process" EXACT [] +synonym: "oxidized flavin-adenine dinucleotide biosynthesis" EXACT [] +synonym: "oxidized flavin-adenine dinucleotide biosynthetic process" EXACT [] +is_a: GO:0046443 ! FAD metabolic process +is_a: GO:0072388 ! flavin adenine dinucleotide biosynthetic process + +[Term] +id: GO:0006748 +name: lipoamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group." [GOC:go_curators] +synonym: "lipoamide metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006749 +name: glutathione metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle." [ISBN:0198506732] +synonym: "glutathione metabolism" EXACT [] +synonym: "oxidized glutathione reduction" NARROW [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0006750 +name: glutathione biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." [GOC:ai, GOC:al, GOC:pde, ISBN:0198506732] +synonym: "glutathione anabolism" EXACT [] +synonym: "glutathione biosynthesis" EXACT [] +synonym: "glutathione formation" EXACT [] +synonym: "glutathione synthesis" EXACT [] +xref: MetaCyc:GLUTATHIONESYN-PWY +is_a: GO:0006749 ! glutathione metabolic process +is_a: GO:0019184 ! nonribosomal peptide biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0006751 +name: glutathione catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." [GOC:ai, ISBN:0198506732] +synonym: "glutathione breakdown" EXACT [] +synonym: "glutathione catabolism" EXACT [] +synonym: "glutathione degradation" EXACT [] +is_a: GO:0006749 ! glutathione metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0006753 +name: nucleoside phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any phosphorylated nucleoside." [GOC:mah] +synonym: "nucleoside phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process + +[Term] +id: GO:0006754 +name: ATP biosynthetic process +namespace: biological_process +alt_id: GO:0006758 +alt_id: GO:0006759 +def: "The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [GOC:go_curators, ISBN:0198506732] +synonym: "ATP anabolism" EXACT [] +synonym: "ATP biosynthesis" EXACT [] +synonym: "ATP formation" EXACT [] +synonym: "ATP regeneration" NARROW [] +synonym: "ATP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009206 ! purine ribonucleoside triphosphate biosynthetic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046034 ! ATP metabolic process + +[Term] +id: GO:0006755 +name: obsolete carbamoyl phosphate-ADP transphosphorylation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because, according to PUMA2, this "pathway" is a single reaction, corresponding to 'carbamate kinase activity ; GO:0008804' (EC:2.7.2.2). +synonym: "carbamoyl phosphate-ADP transphosphorylation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006756 +name: AMP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP." [GOC:ai] +is_a: GO:0006754 ! ATP biosynthetic process +is_a: GO:0046033 ! AMP metabolic process +is_a: GO:0046940 ! nucleoside monophosphate phosphorylation + +[Term] +id: GO:0006757 +name: ATP generation from ADP +namespace: biological_process +def: "The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP." [GOC:ai] +synonym: "ADP phosphorylation" EXACT [GOC:dph] +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +is_a: GO:0046031 ! ADP metabolic process +is_a: GO:0046034 ! ATP metabolic process + +[Term] +id: GO:0006760 +name: folic acid-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units." [GOC:ai, GOC:mah] +synonym: "folate and derivative metabolic process" EXACT [] +synonym: "folate and derivative metabolism" EXACT [] +synonym: "folate-containing compound metabolic process" EXACT [] +synonym: "folate-containing compound metabolism" EXACT [] +synonym: "folic acid and derivative metabolic process" EXACT [] +synonym: "folic acid and derivative metabolism" EXACT [] +synonym: "folic acid-containing compound metabolism" EXACT [] +synonym: "vitamin B9 and derivative metabolic process" EXACT [] +synonym: "vitamin B9 and derivative metabolism" EXACT [] +synonym: "vitamin M and derivative metabolic process" EXACT [] +synonym: "vitamin M and derivative metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0006761 +name: dihydrofolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate." [GOC:ai] +synonym: "7,8-dihydrofolate biosynthesis" EXACT [] +synonym: "7,8-dihydrofolate biosynthetic process" EXACT [] +synonym: "dihydrofolate anabolism" EXACT [] +synonym: "dihydrofolate biosynthesis" EXACT [] +synonym: "dihydrofolate formation" EXACT [] +synonym: "dihydrofolate synthesis" EXACT [] +is_a: GO:0009396 ! folic acid-containing compound biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046452 ! dihydrofolate metabolic process + +[Term] +id: GO:0006762 +name: obsolete dihydrofolate reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "dihydrofolate reduction" EXACT [] +is_obsolete: true +consider: GO:0004146 +consider: GO:0046452 + +[Term] +id: GO:0006766 +name: vitamin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems." [GOC:ai] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "vitamin metabolism" EXACT [] +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0006767 +name: water-soluble vitamin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water." [GOC:jl] +synonym: "water-soluble vitamin metabolism" EXACT [] +is_a: GO:0006766 ! vitamin metabolic process + +[Term] +id: GO:0006768 +name: biotin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [ISBN:0198506732] +synonym: "biotin metabolism" EXACT [] +synonym: "vitamin B7 metabolic process" EXACT [] +synonym: "vitamin B7 metabolism" EXACT [] +synonym: "vitamin H metabolic process" EXACT [] +synonym: "vitamin H metabolism" EXACT [] +xref: Wikipedia:Biotin +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0006769 +name: nicotinamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms." [ISBN:0198506732] +synonym: "niacin metabolic process" RELATED [] +synonym: "niacin metabolism" RELATED [] +synonym: "nicotinamide metabolism" EXACT [] +synonym: "vitamin B3 metabolic process" BROAD [] +synonym: "vitamin B3 metabolism" BROAD [] +xref: MetaCyc:PWY-5083 +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process + +[Term] +id: GO:0006771 +name: riboflavin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "riboflavin metabolism" EXACT [] +synonym: "vitamin B2 metabolic process" EXACT [] +synonym: "vitamin B2 metabolism" EXACT [] +synonym: "vitamin G metabolic process" EXACT [] +synonym: "vitamin G metabolism" EXACT [] +xref: Wikipedia:Riboflavin +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042726 ! flavin-containing compound metabolic process + +[Term] +id: GO:0006772 +name: thiamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:jl, ISBN:0198506732] +synonym: "thiamin metabolic process" EXACT [] +synonym: "thiamin metabolism" EXACT [] +synonym: "thiamine metabolism" EXACT [] +synonym: "vitamin B1 metabolic process" EXACT [] +synonym: "vitamin B1 metabolism" EXACT [] +xref: Wikipedia:Thiamine +is_a: GO:0042723 ! thiamine-containing compound metabolic process + +[Term] +id: GO:0006774 +name: obsolete vitamin B12 reduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "vitamin B12 reduction" EXACT [] +is_obsolete: true +consider: GO:0009235 +consider: GO:0050453 + +[Term] +id: GO:0006775 +name: fat-soluble vitamin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water." [GOC:jl, ISBN:0198506732] +synonym: "fat-soluble vitamin metabolism" EXACT [] +is_a: GO:0006766 ! vitamin metabolic process + +[Term] +id: GO:0006776 +name: vitamin A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "vitamin A metabolism" EXACT [] +is_a: GO:0001523 ! retinoid metabolic process +is_a: GO:0006775 ! fat-soluble vitamin metabolic process + +[Term] +id: GO:0006777 +name: Mo-molybdopterin cofactor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands." [http://www.sunysb.edu/biochem/BIOCHEM/facultypages/schindelin/, ISSN:09498257, PMID:22370186, PMID:23201473] +synonym: "Mo-molybdopterin cofactor anabolism" EXACT [] +synonym: "Mo-molybdopterin cofactor biosynthesis" EXACT [] +synonym: "Mo-molybdopterin cofactor formation" EXACT [] +synonym: "Mo-molybdopterin cofactor synthesis" EXACT [] +synonym: "Moco biosynthesis" EXACT [] +synonym: "Moco biosynthetic process" EXACT [] +synonym: "molybdenum cofactor biosynthetic process" RELATED [] +xref: MetaCyc:PWY-6823 +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019720 ! Mo-molybdopterin cofactor metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: has_part GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex +relationship: has_part GO:0061798 ! GTP 3',8'-cyclase activity +relationship: has_part GO:0061799 ! cyclic pyranopterin monophosphate synthase activity + +[Term] +id: GO:0006778 +name: porphyrin-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group." [GOC:jl, ISBN:0198506732, Wikipedia:Porphyrin#Natural_formation] +synonym: "porphyrin metabolic process" RELATED [] +synonym: "porphyrin metabolism" RELATED [] +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0006779 +name: porphyrin-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group." [GOC:jl, ISBN:0198506732, Wikipedia:Porphyrin#Natural_formation] +synonym: "porphyrin anabolism" RELATED [] +synonym: "porphyrin biosynthesis" RELATED [] +synonym: "porphyrin biosynthetic process" RELATED [] +synonym: "porphyrin formation" RELATED [] +synonym: "porphyrin synthesis" RELATED [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process +is_a: GO:0033014 ! tetrapyrrole biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0006780 +name: uroporphyrinogen III biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of uroporphyrinogen III." [GOC:ai] +synonym: "uroporphyrinogen III anabolism" EXACT [] +synonym: "uroporphyrinogen III biosynthesis" EXACT [] +synonym: "uroporphyrinogen III formation" EXACT [] +synonym: "uroporphyrinogen III synthesis" EXACT [] +is_a: GO:0006779 ! porphyrin-containing compound biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0046502 ! uroporphyrinogen III metabolic process + +[Term] +id: GO:0006781 +name: succinyl-CoA pathway +namespace: biological_process +def: "The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX." [GOC:isa_complete, ISBN:0879010479] +synonym: "biosynthesis of protoporphyrin IX via succinyl CoA" EXACT [] +synonym: "biosynthesis of protoporphyrin IX via succinyl-CoA" EXACT [] +synonym: "biosynthetic process of protoporphyrin IX via succinyl CoA" EXACT [] +synonym: "biosynthetic process of protoporphyrin IX via succinyl-CoA" EXACT [] +synonym: "succinyl CoA pathway" EXACT [] +is_a: GO:0006104 ! succinyl-CoA metabolic process +is_a: GO:0006779 ! porphyrin-containing compound biosynthetic process +relationship: part_of GO:0006780 ! uroporphyrinogen III biosynthetic process + +[Term] +id: GO:0006782 +name: protoporphyrinogen IX biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX." [GOC:go_curators] +synonym: "protoporphyrinogen IX anabolism" EXACT [] +synonym: "protoporphyrinogen IX biosynthesis" EXACT [] +synonym: "protoporphyrinogen IX formation" EXACT [] +synonym: "protoporphyrinogen IX synthesis" EXACT [] +is_a: GO:0006779 ! porphyrin-containing compound biosynthetic process +is_a: GO:0046501 ! protoporphyrinogen IX metabolic process +relationship: part_of GO:0006783 ! heme biosynthetic process + +[Term] +id: GO:0006783 +name: heme biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors." [GOC:jl, PMID:11788607] +synonym: "haem biosynthesis" EXACT [] +synonym: "haem biosynthetic process" EXACT [] +synonym: "heme anabolism" EXACT [] +synonym: "heme biosynthesis" EXACT [] +synonym: "heme formation" EXACT [] +synonym: "heme synthesis" EXACT [] +xref: MetaCyc:HEMESYN2-PWY +is_a: GO:0006779 ! porphyrin-containing compound biosynthetic process +is_a: GO:0042168 ! heme metabolic process +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0006784 +name: heme A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3." [GOC:ai, PMID:11788607] +synonym: "haem A biosynthesis" EXACT [] +synonym: "haem A biosynthetic process" EXACT [] +synonym: "heme A anabolism" EXACT [] +synonym: "heme A biosynthesis" EXACT [] +synonym: "heme A formation" EXACT [] +synonym: "heme A synthesis" EXACT [] +is_a: GO:0006783 ! heme biosynthetic process +is_a: GO:0046160 ! heme a metabolic process + +[Term] +id: GO:0006785 +name: heme B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes." [GOC:yaf, PMID:29414780, UniPathway:UPA00252] +synonym: "haem B biosynthesis" EXACT [] +synonym: "haem B biosynthetic process" EXACT [] +synonym: "heme B anabolism" EXACT [] +synonym: "heme B biosynthesis" EXACT [] +synonym: "heme B formation" EXACT [] +synonym: "heme B synthesis" EXACT [] +synonym: "protoheme biosynthesis" EXACT [] +synonym: "protoheme biosynthetic process" EXACT [] +is_a: GO:0006783 ! heme biosynthetic process +is_a: GO:0046492 ! heme B metabolic process + +[Term] +id: GO:0006786 +name: heme C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f." [GOC:curators, PubChem_Compound:122208] +synonym: "haem C biosynthesis" EXACT [] +synonym: "haem C biosynthetic process" EXACT [] +synonym: "heme C anabolism" EXACT [] +synonym: "heme C biosynthesis" EXACT [] +synonym: "heme C formation" EXACT [] +synonym: "heme C synthesis" EXACT [] +is_a: GO:0006783 ! heme biosynthetic process +is_a: GO:0046162 ! heme C metabolic process + +[Term] +id: GO:0006787 +name: porphyrin-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group." [GOC:jl, ISBN:0198506732] +synonym: "porphyrin breakdown" RELATED [] +synonym: "porphyrin catabolic process" RELATED [] +synonym: "porphyrin catabolism" RELATED [] +synonym: "porphyrin degradation" RELATED [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process +is_a: GO:0033015 ! tetrapyrrole catabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0006788 +name: heme oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme." [GOC:mah] +synonym: "haem oxidation" EXACT [] +is_a: GO:0042168 ! heme metabolic process +is_a: GO:0055114 ! oxidation-reduction process +relationship: part_of GO:0006787 ! porphyrin-containing compound catabolic process + +[Term] +id: GO:0006789 +name: bilirubin conjugation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin." [DOI:10.1016/0305-0491(80)90243-6] +is_a: GO:0006787 ! porphyrin-containing compound catabolic process +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0006790 +name: sulfur compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +synonym: "sulfur metabolism" EXACT [] +synonym: "sulphur metabolic process" EXACT [] +synonym: "sulphur metabolism" EXACT [] +xref: Wikipedia:Sulfur_metabolism +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0006791 +name: sulfur utilization +namespace: biological_process +def: "A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism." [GOC:mah, GOC:mlg] +synonym: "sulphur utilization" EXACT [] +is_a: GO:0008150 ! biological_process +relationship: has_part GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0006792 +name: regulation of sulfur utilization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sulfur utilization." [GOC:go_curators] +synonym: "regulation of sulphur utilization" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006791 ! sulfur utilization +relationship: regulates GO:0006791 ! sulfur utilization + +[Term] +id: GO:0006793 +name: phosphorus metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] +subset: goslim_pir +synonym: "phosphorus metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0006794 +name: phosphorus utilization +namespace: biological_process +def: "A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism." [GOC:mah, GOC:mlg] +is_a: GO:0008150 ! biological_process +relationship: has_part GO:0006793 ! phosphorus metabolic process + +[Term] +id: GO:0006795 +name: regulation of phosphorus utilization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006794 ! phosphorus utilization +relationship: regulates GO:0006794 ! phosphorus utilization + +[Term] +id: GO:0006796 +name: phosphate-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] +synonym: "phosphate metabolic process" RELATED [] +synonym: "phosphate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process + +[Term] +id: GO:0006797 +name: polyphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid." [GOC:go_curators, ISBN:0198506732] +synonym: "polyphosphate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0006798 +name: polyphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid." [GOC:go_curators, ISBN:0198506732] +synonym: "polyphosphate breakdown" EXACT [] +synonym: "polyphosphate catabolism" EXACT [] +synonym: "polyphosphate degradation" EXACT [] +is_a: GO:0006797 ! polyphosphate metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0006799 +name: polyphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid." [ISBN:0198506732] +synonym: "polyphosphate anabolism" EXACT [] +synonym: "polyphosphate biosynthesis" EXACT [] +synonym: "polyphosphate formation" EXACT [] +synonym: "polyphosphate synthesis" EXACT [] +is_a: GO:0006797 ! polyphosphate metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0006800 +name: obsolete oxygen and reactive oxygen species metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH)." [GOC:jl, PMID:12115731] +comment: This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together. +synonym: "oxygen and active oxygen species metabolism" EXACT [] +synonym: "oxygen and AOS metabolism" EXACT [] +synonym: "oxygen and reactive oxidative species metabolism" EXACT [] +synonym: "oxygen and reactive oxygen intermediate metabolism" EXACT [] +synonym: "oxygen and reactive oxygen species metabolic process" EXACT [] +synonym: "oxygen and reactive oxygen species metabolism" EXACT [] +synonym: "oxygen and ROI metabolism" EXACT [] +synonym: "oxygen and ROS metabolic process" EXACT [] +synonym: "oxygen and ROS metabolism" EXACT [] +is_obsolete: true +consider: GO:0072592 +consider: GO:0072593 + +[Term] +id: GO:0006801 +name: superoxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species." [GOC:jl] +synonym: "oxygen free radical metabolic process" EXACT [] +synonym: "oxygen free radical metabolism" EXACT [] +synonym: "superoxide free radical metabolic process" EXACT [] +synonym: "superoxide free radical metabolism" EXACT [] +synonym: "superoxide metabolism" EXACT [] +is_a: GO:0072593 ! reactive oxygen species metabolic process + +[Term] +id: GO:0006802 +name: obsolete catalase reaction +namespace: biological_process +def: "OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O." [GOC:jl, PMID:11245904] +comment: This term was made obsolete because it represents a molecular function. +synonym: "catalase reaction" EXACT [] +synonym: "hydroperoxidase reaction" RELATED [] +is_obsolete: true +consider: GO:0004096 + +[Term] +id: GO:0006803 +name: obsolete glutathione conjugation reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "glutathione conjugation reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0004364 + +[Term] +id: GO:0006804 +name: obsolete peroxidase reaction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "peroxidase reaction" EXACT [] +is_obsolete: true +replaced_by: GO:0004601 + +[Term] +id: GO:0006805 +name: xenobiotic metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide." [GOC:cab2] +subset: goslim_chembl +subset: goslim_pir +synonym: "xenobiotic metabolism" EXACT [] +xref: Wikipedia:Xenobiotic_metabolism +is_a: GO:0044237 ! cellular metabolic process +relationship: part_of GO:0071466 ! cellular response to xenobiotic stimulus + +[Term] +id: GO:0006806 +name: obsolete insecticide resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "insecticide resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0017085 + +[Term] +id: GO:0006807 +name: nitrogen compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "nitrogen compound metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0006808 +name: regulation of nitrogen utilization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nitrogen utilization." [GOC:go_curators] +subset: goslim_metagenomics +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019740 ! nitrogen utilization +relationship: regulates GO:0019740 ! nitrogen utilization + +[Term] +id: GO:0006809 +name: nitric oxide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] +synonym: "nitric oxide anabolism" EXACT [] +synonym: "nitric oxide biosynthesis" EXACT [] +synonym: "nitric oxide formation" EXACT [] +synonym: "nitric oxide synthesis" EXACT [] +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0046209 ! nitric oxide metabolic process +is_a: GO:1903409 ! reactive oxygen species biosynthetic process + +[Term] +id: GO:0006810 +name: transport +namespace: biological_process +alt_id: GO:0015457 +alt_id: GO:0015460 +alt_id: GO:0044765 +def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah] +comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. +subset: gocheck_do_not_annotate +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "single-organism transport" RELATED [] +synonym: "small molecule transport" NARROW [] +synonym: "solute:solute exchange" NARROW [] +is_a: GO:0051234 ! establishment of localization +created_by: jl +creation_date: 2012-12-13T16:25:32Z + +[Term] +id: GO:0006811 +name: ion transport +namespace: biological_process +def: "The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0006810 ! transport + +[Term] +id: GO:0006812 +name: cation transport +namespace: biological_process +alt_id: GO:0006819 +alt_id: GO:0015674 +def: "The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah] +is_a: GO:0006811 ! ion transport + +[Term] +id: GO:0006813 +name: potassium ion transport +namespace: biological_process +alt_id: GO:0015458 +alt_id: GO:0071804 +def: "The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "cellular potassium ion transport" EXACT [] +synonym: "K+ conductance" RELATED [] +synonym: "low voltage-dependent potassium channel auxiliary protein activity" RELATED [GOC:mah] +synonym: "low voltage-gated potassium channel auxiliary protein activity" RELATED [GOC:mah] +synonym: "potassium conductance" NARROW [] +synonym: "potassium ion conductance" NARROW [] +synonym: "potassium transport" RELATED [] +synonym: "sodium/potassium transport" BROAD [] +is_a: GO:0015672 ! monovalent inorganic cation transport +is_a: GO:0030001 ! metal ion transport +created_by: mah +creation_date: 2010-09-03T02:39:22Z + +[Term] +id: GO:0006814 +name: sodium ion transport +namespace: biological_process +alt_id: GO:0006834 +alt_id: GO:0016974 +def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] +synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah] +synonym: "sodium transport" EXACT [] +synonym: "sodium/potassium transport" BROAD [] +synonym: "sodium:calcium exchange" NARROW [] +synonym: "sodium:solute transport" NARROW [] +is_a: GO:0015672 ! monovalent inorganic cation transport +is_a: GO:0030001 ! metal ion transport + +[Term] +id: GO:0006815 +name: obsolete sodium/potassium transport +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it is a composite term that represents two individual processes. +synonym: "sodium/potassium transport" EXACT [] +is_obsolete: true +consider: GO:0006813 +consider: GO:0006814 + +[Term] +id: GO:0006816 +name: calcium ion transport +namespace: biological_process +def: "The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "calcium transport" EXACT [] +synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] +synonym: "sodium:calcium exchange" NARROW [] +is_a: GO:0070838 ! divalent metal ion transport + +[Term] +id: GO:0006817 +name: phosphate ion transport +namespace: biological_process +def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "phosphate transport" RELATED [] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0006820 +name: anion transport +namespace: biological_process +alt_id: GO:0006822 +def: "The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006811 ! ion transport + +[Term] +id: GO:0006821 +name: chloride transport +namespace: biological_process +def: "The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0006823 +name: obsolete heavy metal ion transport +namespace: biological_process +def: "OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:kd, GOC:mah] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "heavy metal ion transport" EXACT [] +is_obsolete: true +consider: GO:0030001 + +[Term] +id: GO:0006824 +name: cobalt ion transport +namespace: biological_process +def: "The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "cobalt transport" EXACT [] +is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0072511 ! divalent inorganic cation transport + +[Term] +id: GO:0006825 +name: copper ion transport +namespace: biological_process +def: "The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0006826 +name: iron ion transport +namespace: biological_process +alt_id: GO:0015681 +alt_id: GO:0015682 +alt_id: GO:0015684 +alt_id: GO:0033216 +alt_id: GO:0097286 +def: "The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "ferric ion import" NARROW [] +synonym: "ferric ion transport" NARROW [] +synonym: "ferric iron import" NARROW [] +synonym: "ferric iron transport" NARROW [] +synonym: "ferric iron uptake" NARROW [] +synonym: "ferrous ion transport" NARROW [] +synonym: "ferrous iron transport" NARROW [] +synonym: "iron ion import" RELATED [] +synonym: "iron transport" EXACT [] +is_a: GO:0000041 ! transition metal ion transport +created_by: pr +creation_date: 2012-04-18T03:33:45Z + +[Term] +id: GO:0006828 +name: manganese ion transport +namespace: biological_process +def: "The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0006829 +name: zinc ion transport +namespace: biological_process +def: "The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "zinc II ion transport" EXACT [] +synonym: "zinc transport" EXACT [GOC:mah] +is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0070838 ! divalent metal ion transport + +[Term] +id: GO:0006832 +name: obsolete small molecule transport +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "small molecule transport" EXACT [] +is_obsolete: true +consider: GO:0006810 + +[Term] +id: GO:0006833 +name: water transport +namespace: biological_process +def: "The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0042044 ! fluid transport + +[Term] +id: GO:0006835 +name: dicarboxylic acid transport +namespace: biological_process +alt_id: GO:0006841 +def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "sodium:dicarboxylate transport" RELATED [] +is_a: GO:0046942 ! carboxylic acid transport + +[Term] +id: GO:0006836 +name: neurotransmitter transport +namespace: biological_process +def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai] +subset: goslim_pir +synonym: "sodium:neurotransmitter transport" NARROW [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0006837 +name: serotonin transport +namespace: biological_process +def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] +is_a: GO:0006812 ! cation transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015844 ! monoamine transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0006838 +name: obsolete allantoin/allantoate transport +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it is a composite term that represents two individual processes. +synonym: "allantoin/allantoate transport" EXACT [] +is_obsolete: true +consider: GO:0015719 +consider: GO:0015720 + +[Term] +id: GO:0006839 +name: mitochondrial transport +namespace: biological_process +def: "Transport of substances into, out of or within a mitochondrion." [GOC:ai] +subset: goslim_drosophila +synonym: "mitochondrial alpha-ketoglutarate/malate transport" NARROW [] +synonym: "mitochondrial aspartate/glutamate transport" NARROW [] +synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0006840 +name: obsolete mitochondrial alpha-ketoglutarate/malate transport +namespace: biological_process +def: "OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion." [GOC:ai] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "mitochondrial alpha-ketoglutarate/malate transport" EXACT [] +synonym: "mitochondrial oxoglutarate/malate transport" EXACT [] +is_obsolete: true +consider: GO:0006839 +consider: GO:0015367 +consider: GO:0015742 +consider: GO:0015743 + +[Term] +id: GO:0006842 +name: tricarboxylic acid transport +namespace: biological_process +def: "The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0046942 ! carboxylic acid transport + +[Term] +id: GO:0006843 +name: mitochondrial citrate transmembrane transport +namespace: biological_process +alt_id: GO:1990541 +def: "The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix." [GOC:ai, PMID:20371607] +synonym: "mitochondrial citrate transport" RELATED [] +is_a: GO:0015746 ! citrate transport +is_a: GO:1990546 ! mitochondrial tricarboxylic acid transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:08:45Z + +[Term] +id: GO:0006844 +name: acyl carnitine transport +namespace: biological_process +def: "The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane." [GOC:ai] +is_a: GO:0015697 ! quaternary ammonium group transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0006845 +name: obsolete mitochondrial aspartate/glutamate transport +namespace: biological_process +def: "OBSOLETE. The directed movement of aspartate and glutamate into, out of or within a mitochondrion." [GOC:ai] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "mitochondrial aspartate/glutamate transport" EXACT [] +is_obsolete: true +consider: GO:0006839 +consider: GO:0015810 +consider: GO:0015813 + +[Term] +id: GO:0006846 +name: acetate transport +namespace: biological_process +def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0006847 +name: plasma membrane acetate transport +namespace: biological_process +def: "The directed movement of acetate across a plasma membrane." [GOC:ai] +is_a: GO:0035433 ! acetate transmembrane transport + +[Term] +id: GO:0006848 +name: pyruvate transport +namespace: biological_process +def: "The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0006849 +name: plasma membrane pyruvate transport +namespace: biological_process +def: "The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane." [GOC:ai] +is_a: GO:1901475 ! pyruvate transmembrane transport + +[Term] +id: GO:0006850 +name: mitochondrial pyruvate transmembrane transport +namespace: biological_process +alt_id: GO:1902361 +def: "The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:vw, PMID:22628558] +synonym: "mitochondrial pyruvate transport" RELATED [] +synonym: "pyruvate membrane transport in mitochondria" RELATED [] +synonym: "pyruvate membrane transport in mitochondrion" RELATED [] +synonym: "pyruvate transmembrane transport in mitochondria" RELATED [] +synonym: "pyruvate transmembrane transport in mitochondrion" RELATED [] +is_a: GO:1901475 ! pyruvate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: dph +creation_date: 2013-08-15T11:19:35Z + +[Term] +id: GO:0006851 +name: mitochondrial calcium ion transmembrane transport +namespace: biological_process +def: "The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:ai] +synonym: "mitochondrial calcium transport" EXACT [] +is_a: GO:0070588 ! calcium ion transmembrane transport + +[Term] +id: GO:0006852 +name: obsolete mitochondrial sodium/calcium ion exchange +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents function rather than a process. +synonym: "mitochondrial sodium/calcium exchange" EXACT [] +synonym: "mitochondrial sodium/calcium ion exchange" EXACT [] +is_obsolete: true +consider: GO:0005432 +consider: GO:0006814 +consider: GO:0006816 +consider: GO:0006839 + +[Term] +id: GO:0006853 +name: carnitine shuttle +namespace: biological_process +def: "The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine." [ISBN:0198547684] +comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. +xref: Wikipedia:Carnitine#Role_in_fatty_acid_metabolism +is_a: GO:0015909 ! long-chain fatty acid transport +is_a: GO:0032365 ! intracellular lipid transport +is_a: GO:1902001 ! fatty acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport + +[Term] +id: GO:0006854 +name: obsolete ATP/ADP exchange +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "ATP/ADP exchange" EXACT [] +is_obsolete: true +replaced_by: GO:0005471 + +[Term] +id: GO:0006855 +name: drug transmembrane transport +namespace: biological_process +def: "The process in which a drug is transported across a membrane." [GOC:ai, GOC:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "drug membrane transport" EXACT [] +synonym: "multidrug transport" RELATED [] +is_a: GO:0015893 ! drug transport +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0006856 +name: eye pigment precursor transport +namespace: biological_process +def: "The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006810 ! transport +relationship: part_of GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0006857 +name: oligopeptide transport +namespace: biological_process +def: "The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [ISBN:0198506732] +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0006858 +name: extracellular transport +namespace: biological_process +def: "The transport of substances that occurs outside cells." [GOC:go_curators] +is_a: GO:0006810 ! transport +intersection_of: GO:0006810 ! transport +intersection_of: occurs_in GO:0005576 ! extracellular region +relationship: occurs_in GO:0005576 ! extracellular region + +[Term] +id: GO:0006859 +name: extracellular carbohydrate transport +namespace: biological_process +def: "The directed extracellular movement of carbohydrates." [GOC:ai] +is_a: GO:0006858 ! extracellular transport +is_a: GO:0008643 ! carbohydrate transport +intersection_of: GO:0008643 ! carbohydrate transport +intersection_of: occurs_in GO:0005576 ! extracellular region + +[Term] +id: GO:0006860 +name: extracellular amino acid transport +namespace: biological_process +def: "The directed extracellular movement of amino acids." [GOC:ai] +is_a: GO:0006858 ! extracellular transport +is_a: GO:0006865 ! amino acid transport +intersection_of: GO:0006865 ! amino acid transport +intersection_of: occurs_in GO:0005576 ! extracellular region + +[Term] +id: GO:0006862 +name: nucleotide transport +namespace: biological_process +def: "The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell." [ISBN:0198506732] +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0006863 +name: purine nucleobase transport +namespace: biological_process +alt_id: GO:0015852 +def: "The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] +synonym: "purine base transmembrane transport" EXACT [GOC:mah] +synonym: "purine base transport" EXACT [GOC:go_curators] +synonym: "purine transmembrane transport" RELATED [GOC:mah] +synonym: "purine transport" RELATED [] +is_a: GO:0015851 ! nucleobase transport + +[Term] +id: GO:0006864 +name: pyrimidine nucleotide transport +namespace: biological_process +def: "The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell." [GOC:ai] +is_a: GO:0006862 ! nucleotide transport + +[Term] +id: GO:0006865 +name: amino acid transport +namespace: biological_process +alt_id: GO:0006866 +def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0006867 +name: asparagine transport +namespace: biological_process +def: "The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-asparagine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0006868 +name: glutamine transport +namespace: biological_process +alt_id: GO:0015815 +def: "The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-glutamine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0006869 +name: lipid transport +namespace: biological_process +def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0071702 ! organic substance transport +relationship: part_of GO:0010876 ! lipid localization + +[Term] +id: GO:0006873 +name: cellular ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of ions at the level of a cell." [GOC:mah] +subset: goslim_yeast +is_a: GO:0050801 ! ion homeostasis +is_a: GO:0055082 ! cellular chemical homeostasis + +[Term] +id: GO:0006874 +name: cellular calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell." [GOC:ceb, GOC:mah] +synonym: "regulation of calcium ion concentration" BROAD [] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0055074 ! calcium ion homeostasis +is_a: GO:0072503 ! cellular divalent inorganic cation homeostasis + +[Term] +id: GO:0006875 +name: cellular metal ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "cellular heavy metal ion homeostasis" NARROW [] +is_a: GO:0030003 ! cellular cation homeostasis +is_a: GO:0055065 ! metal ion homeostasis + +[Term] +id: GO:0006876 +name: cellular cadmium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "cadmium homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055073 ! cadmium ion homeostasis +is_a: GO:0072503 ! cellular divalent inorganic cation homeostasis + +[Term] +id: GO:0006877 +name: cellular cobalt ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "cobalt homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055068 ! cobalt ion homeostasis + +[Term] +id: GO:0006878 +name: cellular copper ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "copper homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055070 ! copper ion homeostasis + +[Term] +id: GO:0006879 +name: cellular iron ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "iron homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055072 ! iron ion homeostasis + +[Term] +id: GO:0006880 +name: intracellular sequestering of iron ion +namespace: biological_process +def: "The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system." [GOC:ai] +synonym: "intracellular iron ion retention" EXACT [] +synonym: "intracellular iron ion sequestering" EXACT [] +synonym: "intracellular iron ion sequestration" EXACT [] +synonym: "intracellular iron ion storage" EXACT [] +synonym: "intracellular retention of iron ion" EXACT [] +synonym: "intracellular sequestration of iron ion" EXACT [] +synonym: "intracellular storage of iron ion" EXACT [] +is_a: GO:0097577 ! sequestering of iron ion + +[Term] +id: GO:0006881 +name: extracellular sequestering of iron ion +namespace: biological_process +def: "The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system." [GOC:ai, GOC:cjm] +synonym: "extracellular iron ion retention" EXACT [] +synonym: "extracellular iron ion sequestering" EXACT [] +synonym: "extracellular iron ion sequestration" EXACT [] +synonym: "extracellular iron ion storage" EXACT [] +synonym: "extracellular retention of iron ion" EXACT [] +synonym: "extracellular sequestration of iron ion" EXACT [] +synonym: "extracellular storage of iron ion" EXACT [] +is_a: GO:0097577 ! sequestering of iron ion + +[Term] +id: GO:0006882 +name: cellular zinc ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell." [GOC:ai, GOC:mah] +synonym: "zinc homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055069 ! zinc ion homeostasis +is_a: GO:0072503 ! cellular divalent inorganic cation homeostasis + +[Term] +id: GO:0006883 +name: cellular sodium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell." [GOC:ai, GOC:mah] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0030004 ! cellular monovalent inorganic cation homeostasis +is_a: GO:0055078 ! sodium ion homeostasis + +[Term] +id: GO:0006884 +name: cell volume homeostasis +namespace: biological_process +def: "Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "regulation of cell volume" EXACT [GOC:dph, GOC:tb] +is_a: GO:0008361 ! regulation of cell size +is_a: GO:0019725 ! cellular homeostasis + +[Term] +id: GO:0006885 +name: regulation of pH +namespace: biological_process +def: "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "hydrogen ion homeostasis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0055067 ! monovalent inorganic cation homeostasis + +[Term] +id: GO:0006886 +name: intracellular protein transport +namespace: biological_process +alt_id: GO:0032779 +def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] +synonym: "copper-induced intracellular protein transport" RELATED [GOC:al] +is_a: GO:0015031 ! protein transport +is_a: GO:0046907 ! intracellular transport +relationship: part_of GO:0034613 ! cellular protein localization + +[Term] +id: GO:0006887 +name: exocytosis +namespace: biological_process +alt_id: GO:0016194 +alt_id: GO:0016195 +def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285] +subset: goslim_yeast +synonym: "nonselective vesicle exocytosis" RELATED [] +synonym: "vesicle exocytosis" EXACT [] +xref: Wikipedia:Exocytosis +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0032940 ! secretion by cell +relationship: has_part GO:0099500 ! vesicle fusion to plasma membrane + +[Term] +id: GO:0006888 +name: endoplasmic reticulum to Golgi vesicle-mediated transport +namespace: biological_process +alt_id: GO:0048221 +def: "The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi." [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb, ISBN:0716731363] +synonym: "anterograde (ER to Golgi) transport" EXACT [] +synonym: "anterograde transport, endoplasmic reticulum to Golgi" EXACT [] +synonym: "anterograde transport, ER to Golgi" EXACT [] +synonym: "anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi" EXACT [] +synonym: "anterograde vesicle-mediated transport, ER to Golgi" EXACT [] +synonym: "endoplasmic reticulum to Golgi transport" EXACT [] +synonym: "endoplasmic reticulum to Golgi vesicle-mediated transport" EXACT [] +synonym: "ER to Golgi transport" EXACT [] +synonym: "ER to Golgi vesicle-mediated transport" EXACT [] +synonym: "rough endoplasmic reticulum to cis-Golgi transport" EXACT [] +synonym: "rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" EXACT [] +synonym: "rough ER to cis-Golgi transport" EXACT [] +synonym: "rough ER to cis-Golgi vesicle-mediated transport" EXACT [] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0048193 ! Golgi vesicle transport +relationship: occurs_in GO:0005737 ! cytoplasm + +[Term] +id: GO:0006889 +name: obsolete regulation of calcium in ER +namespace: biological_process +def: "OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum." [GOC:go_curators] +comment: This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). +synonym: "regulation of calcium in ER" EXACT [] +is_obsolete: true +consider: GO:0005783 +consider: GO:0006874 + +[Term] +id: GO:0006890 +name: retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +namespace: biological_process +alt_id: GO:0048220 +def: "The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG." [ISBN:0716731363, PMID:16510524] +synonym: "cis-Golgi to rough endoplasmic reticulum transport" EXACT [] +synonym: "cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport" EXACT [] +synonym: "cis-Golgi to rough ER transport" EXACT [] +synonym: "cis-Golgi to rough ER vesicle-mediated transport" EXACT [] +synonym: "retrograde (Golgi to ER) transport" EXACT [] +synonym: "retrograde transport, Golgi to endoplasmic reticulum" EXACT [] +synonym: "retrograde transport, Golgi to ER" EXACT [] +synonym: "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum" RELATED [] +synonym: "retrograde vesicle-mediated transport, Golgi to ER" EXACT [] +is_a: GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0006891 +name: intra-Golgi vesicle-mediated transport +namespace: biological_process +def: "The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network)." [ISBN:0716731363] +synonym: "intra-Golgi transport" EXACT [] +is_a: GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0006892 +name: post-Golgi vesicle-mediated transport +namespace: biological_process +def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah] +synonym: "post-Golgi transport" EXACT [] +is_a: GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0006893 +name: Golgi to plasma membrane transport +namespace: biological_process +def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363] +synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT [] +is_a: GO:0006892 ! post-Golgi vesicle-mediated transport +is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane + +[Term] +id: GO:0006894 +name: obsolete Golgi to secretory vesicle transport +namespace: biological_process +def: "OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release." [ISBN:0716731363] +comment: This term was made obsolete because it mixes two processes that can be better captured in separate terms. +synonym: "Golgi to secretory vesicle transport" EXACT [] +synonym: "Golgi to secretory vesicle transport, vesicle-mediated" EXACT [] +is_obsolete: true +consider: GO:0055107 +consider: GO:0055108 + +[Term] +id: GO:0006895 +name: Golgi to endosome transport +namespace: biological_process +alt_id: GO:0048218 +def: "The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes." [GOC:jl, ISBN:0716731363, PMID:10873832] +synonym: "Golgi to endosome vesicle-mediated transport" EXACT [] +synonym: "TGN to endosome transport" EXACT [] +synonym: "trans-Golgi to endosome transport" EXACT [] +is_a: GO:0006892 ! post-Golgi vesicle-mediated transport +is_a: GO:0016482 ! cytosolic transport + +[Term] +id: GO:0006896 +name: Golgi to vacuole transport +namespace: biological_process +def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai] +synonym: "Golgi to vacuole vesicle-mediated transport" EXACT [] +is_a: GO:0006892 ! post-Golgi vesicle-mediated transport +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0006897 +name: endocytosis +namespace: biological_process +alt_id: GO:0016193 +alt_id: GO:0016196 +alt_id: GO:0098701 +def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363] +subset: goslim_yeast +synonym: "endocytic import into cell" EXACT [] +synonym: "nonselective vesicle endocytosis" RELATED [] +synonym: "plasma membrane invagination" NARROW [] +synonym: "vesicle endocytosis" EXACT [] +xref: Wikipedia:Endocytosis +is_a: GO:0016192 ! vesicle-mediated transport +relationship: has_part GO:0006900 ! vesicle budding from membrane +relationship: has_part GO:0010324 ! membrane invagination + +[Term] +id: GO:0006898 +name: receptor-mediated endocytosis +namespace: biological_process +def: "An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles." [GOC:mah, ISBN:0716731363] +synonym: "receptor mediated endocytosis" EXACT [] +xref: Wikipedia:Receptor-mediated_endocytosis +is_a: GO:0006897 ! endocytosis + +[Term] +id: GO:0006900 +name: vesicle budding from membrane +namespace: biological_process +alt_id: GO:0006902 +alt_id: GO:1902591 +def: "The evagination of a membrane, resulting in formation of a vesicle." [GOC:jid, GOC:tb] +synonym: "membrane evagination" EXACT [] +synonym: "nonselective vesicle assembly" RELATED [] +synonym: "single organism membrane budding" RELATED [GOC:TermGenie] +synonym: "single-organism membrane budding" RELATED [] +synonym: "vesicle biosynthesis" EXACT [] +synonym: "vesicle budding" RELATED [] +synonym: "vesicle formation" EXACT [] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0016192 ! vesicle-mediated transport +created_by: jl +creation_date: 2013-12-19T15:26:17Z + +[Term] +id: GO:0006901 +name: vesicle coating +namespace: biological_process +def: "A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination." [GOC:jid] +synonym: "vesicle coat assembly" BROAD [] +is_a: GO:0016050 ! vesicle organization +relationship: part_of GO:0006900 ! vesicle budding from membrane + +[Term] +id: GO:0006903 +name: vesicle targeting +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0016192 ! vesicle-mediated transport +relationship: part_of GO:0051650 ! establishment of vesicle localization + +[Term] +id: GO:0006904 +name: vesicle docking involved in exocytosis +namespace: biological_process +def: "The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis." [GOC:aruk, GOC:bc, GOC:jid, PMID:22438915] +synonym: "vesicle docking during exocytosis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0048278 ! vesicle docking +is_a: GO:0140029 ! exocytic process +intersection_of: GO:0048278 ! vesicle docking +intersection_of: part_of GO:0006887 ! exocytosis + +[Term] +id: GO:0006905 +name: obsolete vesicle transport +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "vesicle transport" EXACT [] +is_obsolete: true +consider: GO:0016192 + +[Term] +id: GO:0006906 +name: vesicle fusion +namespace: biological_process +def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0090174 ! organelle membrane fusion +relationship: part_of GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0006907 +name: pinocytosis +namespace: biological_process +alt_id: GO:0006908 +alt_id: GO:1902536 +def: "An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane." [ISBN:0198506732] +synonym: "clathrin-independent pinocytosis" BROAD [] +synonym: "fluid-phase endocytosis" EXACT [] +synonym: "single-organism pinocytosis" RELATED [] +xref: Wikipedia:Pinocytosis +is_a: GO:0006897 ! endocytosis +created_by: jl +creation_date: 2013-12-02T14:14:38Z + +[Term] +id: GO:0006909 +name: phagocytosis +namespace: biological_process +def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] +xref: Wikipedia:Phagocytosis +is_a: GO:0016192 ! vesicle-mediated transport +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0006910 +name: phagocytosis, recognition +namespace: biological_process +def: "The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell." [GOC:curators, ISBN:0781735149] +comment: Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'. +synonym: "recognition of phagocytosed substance by phagocytic cell" EXACT [] +is_a: GO:0008037 ! cell recognition +intersection_of: GO:0008037 ! cell recognition +intersection_of: part_of GO:0006909 ! phagocytosis +relationship: has_part GO:0038024 ! cargo receptor activity +relationship: part_of GO:0006897 ! endocytosis +relationship: part_of GO:0006909 ! phagocytosis + +[Term] +id: GO:0006911 +name: phagocytosis, engulfment +namespace: biological_process +def: "The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis." [GOC:curators, ISBN:0781735149] +synonym: "phagosome biosynthesis" RELATED [] +synonym: "phagosome formation" RELATED [] +is_a: GO:0099024 ! plasma membrane invagination +intersection_of: GO:0099024 ! plasma membrane invagination +intersection_of: part_of GO:0006909 ! phagocytosis +relationship: part_of GO:0006897 ! endocytosis +relationship: part_of GO:0006909 ! phagocytosis + +[Term] +id: GO:0006912 +name: obsolete phagosome formation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:hjd] +comment: This term was made obsolete because of the ambiguity in its meaning. +synonym: "phagosome formation" EXACT [] +is_obsolete: true +consider: GO:0001845 +consider: GO:0006911 + +[Term] +id: GO:0006913 +name: nucleocytoplasmic transport +namespace: biological_process +alt_id: GO:0000063 +def: "The directed movement of molecules between the nucleus and the cytoplasm." [GOC:go_curators] +comment: Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pombe +synonym: "nucleocytoplasmic shuttling" NARROW [] +is_a: GO:0051169 ! nuclear transport + +[Term] +id: GO:0006914 +name: autophagy +namespace: biological_process +alt_id: GO:0016238 +def: "The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation." [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:9412464] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +xref: Wikipedia:Autophagy_(cellular) +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0061919 ! process utilizing autophagic mechanism + +[Term] +id: GO:0006915 +name: apoptotic process +namespace: biological_process +alt_id: GO:0006917 +alt_id: GO:0008632 +def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] +subset: goslim_pombe +synonym: "activation of apoptosis" NARROW [] +synonym: "apoptosis" NARROW [] +synonym: "apoptosis activator activity" RELATED [] +synonym: "apoptosis signaling" NARROW [] +synonym: "apoptotic cell death" EXACT [GOC:sl] +synonym: "apoptotic program" NARROW [GOC:add] +synonym: "apoptotic programmed cell death" EXACT [] +synonym: "caspase-dependent programmed cell death" RELATED [] +synonym: "cell suicide" BROAD [] +synonym: "cellular suicide" BROAD [] +synonym: "commitment to apoptosis" RELATED [] +synonym: "induction of apoptosis" RELATED [] +synonym: "induction of apoptosis by p53" RELATED [] +synonym: "programmed cell death by apoptosis" EXACT [] +synonym: "signaling (initiator) caspase activity" RELATED [] +synonym: "type I programmed cell death" NARROW [] +xref: Wikipedia:Apoptosis +is_a: GO:0012501 ! programmed cell death + +[Term] +id: GO:0006918 +name: obsolete induction of apoptosis by p53 +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more accurate terms were created. +synonym: "induction of apoptosis by p53" EXACT [] +is_obsolete: true +consider: GO:0006915 + +[Term] +id: GO:0006919 +name: activation of cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process." [GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase] +comment: This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase. +synonym: "activation of caspase activity" NARROW [] +synonym: "activation of metacaspase activity" NARROW [] +synonym: "caspase activation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043280 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0006920 +name: obsolete commitment to apoptosis +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more accurate terms were created. +synonym: "commitment to apoptosis" EXACT [] +is_obsolete: true +consider: GO:0006915 + +[Term] +id: GO:0006921 +name: cellular component disassembly involved in execution phase of apoptosis +namespace: biological_process +def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb] +synonym: "cellular component disassembly involved in apoptosis" NARROW [] +synonym: "cellular component disassembly involved in apoptotic process" BROAD [] +synonym: "disassembly of cell structures" BROAD [] +is_a: GO:0022411 ! cellular component disassembly +intersection_of: GO:0022411 ! cellular component disassembly +intersection_of: part_of GO:0097194 ! execution phase of apoptosis +relationship: part_of GO:0097194 ! execution phase of apoptosis + +[Term] +id: GO:0006922 +name: obsolete cleavage of lamin involved in execution phase of apoptosis +namespace: biological_process +def: "OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina." [GOC:mah, GOC:mtg_apoptosis, ISBN:0815332181] +comment: This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'. +synonym: "cleavage of lamin" BROAD [] +synonym: "cleavage of lamin involved in execution phase of apoptosis" EXACT [] +is_obsolete: true +consider: GO:0097200 + +[Term] +id: GO:0006923 +name: obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis +namespace: biological_process +def: "OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0815332181] +comment: This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'. +synonym: "apoptotic cleavage of cytoskeletal proteins" EXACT [] +synonym: "cleavage of cytoskeletal proteins involved in apoptosis" BROAD [] +synonym: "cleavage of cytoskeletal proteins involved in execution phase of apoptosis" EXACT [] +is_obsolete: true +consider: GO:0097200 + +[Term] +id: GO:0006924 +name: activation-induced cell death of T cells +namespace: biological_process +def: "A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196, PMID:12414721, PMID:12752672] +synonym: "activated T cell apoptosis" BROAD [GOC:add] +synonym: "activation-induced cell death of T lymphocytes" EXACT [GOC:add] +synonym: "activation-induced cell death of T-cells" EXACT [GOC:add] +synonym: "activation-induced cell death of T-lymphocytes" EXACT [GOC:add] +synonym: "AICD" BROAD [GOC:add] +synonym: "antigen-driven apoptosis" BROAD [GOC:add] +is_a: GO:0070231 ! T cell apoptotic process +relationship: part_of GO:0043029 ! T cell homeostasis + +[Term] +id: GO:0006925 +name: inflammatory cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage." [GOC:jl, GOC:mtg_apoptosis, http://www.mercksource.com/] +synonym: "apoptosis of inflammatory cells" EXACT [] +synonym: "inflammatory cell apoptosis" NARROW [] +synonym: "inflammatory cell programmed cell death by apoptosis" EXACT [] +synonym: "killing of inflammatory cells" EXACT [] +synonym: "programmed cell death of inflammatory cells by apoptosis" EXACT [] +synonym: "programmed cell death, inflammatory cells" EXACT [] +is_a: GO:0006915 ! apoptotic process + +[Term] +id: GO:0006926 +name: obsolete virus-infected cell apoptotic process +namespace: biological_process +def: "OBSOLETE. Any apoptotic process in a cell infected with a virus." [GOC:jl, GOC:mtg_apoptosis] +comment: This term was made obsolete because the meaning of the term is ambiguous, as it's possibly conflating at least two scenarios: 1) the organism apoptoses its own cell because it detects it is infected with a virus; 2) the virus induces apoptosis so the cell is lysed and the virus disseminated. Please consider using viral process terms to annotate viral proteins. As for the cellular apoptotic process, this likely occurs via the same mechanisms described by existing apoptotic process terms, so please consider using those to annotate cellular proteins. +synonym: "apoptosis of virus-infected cells" EXACT [] +synonym: "killing virus-infected cells" EXACT [] +synonym: "programmed cell death of virus-infected cells by apoptosis" EXACT [] +synonym: "programmed cell death, virus-infected cells" EXACT [] +synonym: "virus-infected cell apoptosis" NARROW [] +synonym: "virus-infected cell apoptotic process" EXACT [] +synonym: "virus-infected cell programmed cell death by apoptosis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006927 +name: obsolete transformed cell apoptotic process +namespace: biological_process +def: "OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm." [GOC:jl, GOC:mtg_apoptosis] +comment: This term was made obsolete because it does not refer to a normal process. +synonym: "apoptosis of transformed cells" EXACT [] +synonym: "killing transformed cells" EXACT [] +synonym: "programmed cell death of transformed cells by apoptosis" EXACT [] +synonym: "programmed cell death, transformed cells" EXACT [] +synonym: "transformed cell apoptosis" NARROW [] +synonym: "transformed cell programmed cell death by apoptosis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006928 +name: movement of cell or subcellular component +namespace: biological_process +def: "The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore." [GOC:dgh, GOC:dph, GOC:jl, GOC:mlg] +comment: Note that in GO cellular components include whole cells (cell is_a cellular component). +subset: gocheck_do_not_annotate +subset: goslim_pir +synonym: "cell movement" RELATED [] +synonym: "cellular component motion" EXACT [GOC:dph, GOC:jl] +synonym: "cellular component movement" EXACT [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0006929 +name: substrate-dependent cell migration +namespace: biological_process +def: "The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate." [ISBN:0815316194, PMID:11944043, PMID:14657486] +synonym: "substrate-bound cell migration" EXACT [] +is_a: GO:0016477 ! cell migration + +[Term] +id: GO:0006930 +name: substrate-dependent cell migration, cell extension +namespace: biological_process +def: "The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell." [ISBN:0815316194, PMID:11944043, PMID:14657486] +synonym: "substrate-bound cell migration, cell extension" EXACT [] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: part_of GO:0006929 ! substrate-dependent cell migration + +[Term] +id: GO:0006931 +name: substrate-dependent cell migration, cell attachment to substrate +namespace: biological_process +def: "The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions." [ISBN:0815316194, PMID:11944043, PMID:14657486] +synonym: "substrate-bound cell migration, cell attachment to substrate" EXACT [] +is_a: GO:0031589 ! cell-substrate adhesion +relationship: part_of GO:0006929 ! substrate-dependent cell migration + +[Term] +id: GO:0006932 +name: substrate-dependent cell migration, cell contraction +namespace: biological_process +def: "The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves." [ISBN:0815316194, PMID:11944043, PMID:14657486] +synonym: "substrate-bound cell migration, cell contraction" EXACT [] +is_a: GO:0060327 ! cytoplasmic actin-based contraction involved in cell motility +relationship: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0006929 ! substrate-dependent cell migration + +[Term] +id: GO:0006933 +name: negative regulation of cell adhesion involved in substrate-bound cell migration +namespace: biological_process +def: "The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction." [GOC:dph, GOC:tb, ISBN:0815316194, PMID:11944043, PMID:14657486] +synonym: "substrate-bound cell migration, cell release from substrate" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007162 ! negative regulation of cell adhesion +intersection_of: GO:0007162 ! negative regulation of cell adhesion +intersection_of: part_of GO:0006929 ! substrate-dependent cell migration +relationship: part_of GO:0006929 ! substrate-dependent cell migration + +[Term] +id: GO:0006934 +name: substrate-bound cell migration, adhesion receptor recycling +namespace: biological_process +def: "The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions." [PMID:11944043] +is_a: GO:0001881 ! receptor recycling +relationship: part_of GO:0006933 ! negative regulation of cell adhesion involved in substrate-bound cell migration + +[Term] +id: GO:0006935 +name: chemotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [ISBN:0198506732] +synonym: "taxis in response to chemical stimulus" EXACT [] +xref: Wikipedia:Chemotaxis +is_a: GO:0042330 ! taxis +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0006936 +name: muscle contraction +namespace: biological_process +def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732] +subset: goslim_pir +xref: Wikipedia:Muscle_contraction +is_a: GO:0003012 ! muscle system process + +[Term] +id: GO:0006937 +name: regulation of muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators] +is_a: GO:0090257 ! regulation of muscle system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006936 ! muscle contraction +relationship: regulates GO:0006936 ! muscle contraction + +[Term] +id: GO:0006939 +name: smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732] +synonym: "visceral muscle contraction" EXACT [] +is_a: GO:0006936 ! muscle contraction + +[Term] +id: GO:0006940 +name: regulation of smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] +is_a: GO:0006937 ! regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006939 ! smooth muscle contraction +relationship: regulates GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0006941 +name: striated muscle contraction +namespace: biological_process +def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732] +synonym: "sarcomeric muscle contraction" EXACT [] +is_a: GO:0006936 ! muscle contraction + +[Term] +id: GO:0006942 +name: regulation of striated muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] +is_a: GO:0006937 ! regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006941 ! striated muscle contraction +relationship: regulates GO:0006941 ! striated muscle contraction + +[Term] +id: GO:0006943 +name: obsolete chemi-mechanical coupling +namespace: biological_process +def: "OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle)." [GOC:jid, http://www.m-w.com] +comment: This term was made obsolete because its meaning is vague, and it does not fit with other terms in GO. +synonym: "chemi-mechanical coupling" EXACT [] +synonym: "mechanochemical coupling" EXACT [] +is_obsolete: true +consider: GO:0009612 +consider: GO:0050954 + +[Term] +id: GO:0006945 +name: obsolete nuclear fusion during karyogamy +namespace: biological_process +def: "OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process." [PMID:9442101] +comment: This term was made obsolete because it is redundant outside the context of Saccharomyces biology. +synonym: "nuclear fusion during karyogamy" EXACT [] +is_obsolete: true +consider: GO:0000741 + +[Term] +id: GO:0006948 +name: induction by virus of host cell-cell fusion +namespace: biological_process +def: "The process of syncytia-forming cell-cell fusion, caused by a virus." [ISBN:0781718325] +comment: Where syncytium formation results in the spread of virus in the host, also consider annotating to the term 'spread of virus in multicellular host ; GO:0046739'. +synonym: "induction by virus of cell-cell fusion in host" EXACT [] +synonym: "viral-induced cell-cell fusion" EXACT [] +synonym: "viral-induced host cell-cell fusion" EXACT [] +synonym: "viral-induced membrane fusion" NARROW [] +is_a: GO:0019054 ! modulation by virus of host cellular process + +[Term] +id: GO:0006949 +name: syncytium formation +namespace: biological_process +def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732] +subset: goslim_pir +is_a: GO:0009987 ! cellular process +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0006950 +name: response to stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_plant +synonym: "response to abiotic stress" RELATED [] +synonym: "response to biotic stress" RELATED [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0006952 +name: defense response +namespace: biological_process +alt_id: GO:0002217 +alt_id: GO:0042829 +def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] +synonym: "antimicrobial peptide activity" RELATED [] +synonym: "defence response" EXACT [] +synonym: "defense/immunity protein activity" RELATED [] +synonym: "physiological defense response" EXACT [] +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0006953 +name: acute-phase response +namespace: biological_process +def: "An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals." [ISBN:0198506732] +is_a: GO:0002526 ! acute inflammatory response + +[Term] +id: GO:0006954 +name: inflammatory response +namespace: biological_process +def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732] +synonym: "inflammation" BROAD [] +xref: Wikipedia:Inflammation +is_a: GO:0006952 ! defense response + +[Term] +id: GO:0006955 +name: immune response +namespace: biological_process +def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add] +subset: goslim_drosophila +is_a: GO:0002376 ! immune system process +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0006956 +name: complement activation +namespace: biological_process +def: "Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "complement activity" RELATED [] +synonym: "complement cascade" EXACT [GOC:add] +synonym: "complement response" EXACT [] +is_a: GO:0002252 ! immune effector process +is_a: GO:0002253 ! activation of immune response +is_a: GO:0006959 ! humoral immune response +relationship: has_part GO:0072376 ! protein activation cascade + +[Term] +id: GO:0006957 +name: complement activation, alternative pathway +namespace: biological_process +def: "Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes." [GOC:add, ISBN:0781735149] +synonym: "complement cascade, alternative pathway" EXACT [GOC:add] +is_a: GO:0006956 ! complement activation +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0006958 +name: complement activation, classical pathway +namespace: biological_process +def: "Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes." [GOC:add, ISBN:0781735149] +synonym: "complement cascade, classical pathway" EXACT [GOC:add] +is_a: GO:0006956 ! complement activation +relationship: part_of GO:0002455 ! humoral immune response mediated by circulating immunoglobulin + +[Term] +id: GO:0006959 +name: humoral immune response +namespace: biological_process +def: "An immune response mediated through a body fluid." [GOC:hb, ISBN:0198506732] +xref: Wikipedia:Humoral_immunity +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0006962 +name: male-specific antibacterial humoral response +namespace: biological_process +def: "An immune response against bacteria, specific to males and mediated through a body fluid." [GOC:go_curators] +is_a: GO:0019731 ! antibacterial humoral response +is_a: GO:0050831 ! male-specific defense response to bacterium + +[Term] +id: GO:0006963 +name: positive regulation of antibacterial peptide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:mah, PMID:10973475] +synonym: "activation of antibacterial peptide biosynthetic process" NARROW [] +synonym: "antibacterial peptide induction" EXACT [] +synonym: "antibacterial polypeptide induction" EXACT [] +synonym: "stimulation of antibacterial peptide biosynthetic process" NARROW [] +synonym: "up regulation of antibacterial peptide biosynthetic process" EXACT [] +synonym: "up-regulation of antibacterial peptide biosynthetic process" EXACT [] +synonym: "upregulation of antibacterial peptide biosynthetic process" EXACT [] +is_a: GO:0002803 ! positive regulation of antibacterial peptide production +is_a: GO:0002807 ! positive regulation of antimicrobial peptide biosynthetic process +is_a: GO:0002808 ! regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002780 ! antibacterial peptide biosynthetic process +relationship: positively_regulates GO:0002780 ! antibacterial peptide biosynthetic process + +[Term] +id: GO:0006964 +name: positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:mah, PMID:10973475] +synonym: "activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] +synonym: "anti-Gram-negative bacterial peptide induction" EXACT [] +synonym: "anti-Gram-negative bacterial polypeptide induction" EXACT [] +synonym: "stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] +synonym: "up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +synonym: "up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +synonym: "upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] +is_a: GO:0002813 ! regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria +is_a: GO:0006963 ! positive regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria +relationship: positively_regulates GO:0002812 ! biosynthetic process of antibacterial peptides active against Gram-negative bacteria + +[Term] +id: GO:0006965 +name: positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:mah, PMID:10973475] +synonym: "activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] +synonym: "anti-Gram-positive bacterial peptide induction" EXACT [] +synonym: "anti-Gram-positive bacterial polypeptide induction" EXACT [] +synonym: "stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] +synonym: "up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +synonym: "up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +synonym: "upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] +is_a: GO:0002816 ! regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria +is_a: GO:0006963 ! positive regulation of antibacterial peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria +relationship: positively_regulates GO:0002815 ! biosynthetic process of antibacterial peptides active against Gram-positive bacteria + +[Term] +id: GO:0006967 +name: positive regulation of antifungal peptide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:mah] +synonym: "activation of antifungal peptide biosynthetic process" NARROW [] +synonym: "antifungal peptide induction" EXACT [] +synonym: "antifungal polypeptide induction" EXACT [] +synonym: "stimulation of antifungal peptide biosynthetic process" NARROW [] +synonym: "up regulation of antifungal peptide biosynthetic process" EXACT [] +synonym: "up-regulation of antifungal peptide biosynthetic process" EXACT [] +synonym: "upregulation of antifungal peptide biosynthetic process" EXACT [] +is_a: GO:0002804 ! positive regulation of antifungal peptide production +is_a: GO:0002807 ! positive regulation of antimicrobial peptide biosynthetic process +is_a: GO:0002810 ! regulation of antifungal peptide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002783 ! antifungal peptide biosynthetic process +relationship: positively_regulates GO:0002783 ! antifungal peptide biosynthetic process + +[Term] +id: GO:0006968 +name: cellular defense response +namespace: biological_process +alt_id: GO:0002818 +alt_id: GO:0016066 +alt_id: GO:0016067 +def: "A defense response that is mediated by cells." [GOC:ebc] +synonym: "cellular defence response" EXACT [] +synonym: "intracellular defence response" NARROW [] +synonym: "intracellular defense response" NARROW [] +is_a: GO:0006952 ! defense response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18111 xsd:anyURI + +[Term] +id: GO:0006969 +name: obsolete melanotic tumor response +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:add] +comment: This term was made obsolete because it was undefined and represented an abnormal process. +synonym: "melanotic mass response" EXACT [] +synonym: "melanotic tumor response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0006970 +name: response to osmotic stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:jl] +subset: goslim_yeast +synonym: "osmotic response" EXACT [] +synonym: "osmotic stress response" EXACT [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0006971 +name: hypotonic response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell." [GOC:jl, PMID:12598593] +synonym: "hypo-osmotic response" EXACT [] +is_a: GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0006972 +name: hyperosmotic response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell." [GOC:jl, PMID:12142009] +synonym: "HOG response" EXACT [] +synonym: "hypertonic response" EXACT [] +synonym: "response to hypertonicity" EXACT [GOC:mah, GOC:yaf] +is_a: GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0006973 +name: intracellular accumulation of glycerol +namespace: biological_process +def: "The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment." [GOC:jl, PMID:11752666] +is_a: GO:0019725 ! cellular homeostasis +relationship: part_of GO:0071474 ! cellular hyperosmotic response + +[Term] +id: GO:0006974 +name: cellular response to DNA damage stimulus +namespace: biological_process +alt_id: GO:0034984 +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." [GOC:go_curators] +subset: goslim_yeast +synonym: "cellular DNA damage response" EXACT [] +synonym: "DNA damage response" EXACT [] +synonym: "response to DNA damage stimulus" BROAD [] +synonym: "response to genotoxic stress" EXACT [] +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0006975 +name: DNA damage induced protein phosphorylation +namespace: biological_process +def: "The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage." [GOC:go_curators] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0006974 ! cellular response to DNA damage stimulus + +[Term] +id: GO:0006977 +name: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest +namespace: biological_process +def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle." [GOC:go_curators] +synonym: "positive regulation of cell cycle arrest by p53-mediated DNA damage response" EXACT [GOC:dph, GOC:mah] +is_a: GO:0030330 ! DNA damage response, signal transduction by p53 class mediator +is_a: GO:0071158 ! positive regulation of cell cycle arrest +is_a: GO:0072431 ! signal transduction involved in mitotic G1 DNA damage checkpoint + +[Term] +id: GO:0006978 +name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +namespace: biological_process +def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage." [PMID:10967424] +is_a: GO:0030330 ! DNA damage response, signal transduction by p53 class mediator +is_a: GO:0042772 ! DNA damage response, signal transduction resulting in transcription + +[Term] +id: GO:0006979 +name: response to oxidative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl, PMID:12115731] +subset: goslim_yeast +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0006981 +name: obsolete activation of SoxR protein +namespace: biological_process +def: "OBSOLETE. The conversion of the SoxR transcription factor to its active (oxidized) form." [GOC:jl, PMID:8816757] +comment: This term was made obsolete because it was too specific with respect to a single gene product. +is_obsolete: true + +[Term] +id: GO:0006982 +name: response to lipid hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids." [GOC:jl, PMID:10944149] +synonym: "response to LHPO" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0033194 ! response to hydroperoxide + +[Term] +id: GO:0006983 +name: ER overload response +namespace: biological_process +alt_id: GO:0006985 +def: "The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB." [PMID:10390516] +synonym: "endoplasmic reticulum overload response" EXACT [] +synonym: "EOR" EXACT [] +synonym: "EOR-mediated activation of NF-kappaB" NARROW [GOC:dph, GOC:tb] +synonym: "EOR-mediated NF-kappaB activation" NARROW [] +synonym: "ER-overload response" EXACT [] +synonym: "positive regulation of NF-kappaB transcription factor activity by EOR" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of NF-kappaB transcription factor activity by ER overload response" NARROW [] +is_a: GO:0006984 ! ER-nucleus signaling pathway +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0071216 ! cellular response to biotic stimulus + +[Term] +id: GO:0006984 +name: ER-nucleus signaling pathway +namespace: biological_process +def: "Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation." [GOC:mah] +synonym: "endoplasmic reticulum to nucleus signaling pathway" EXACT [] +synonym: "endoplasmic reticulum-nuclear signaling pathway" EXACT [] +synonym: "ER to nucleus signaling pathway" EXACT [] +synonym: "ER to nucleus signalling pathway" EXACT [] +synonym: "ER-nuclear signaling pathway" EXACT [] +synonym: "ER-nuclear signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0006986 +name: response to unfolded protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." [GOC:jl] +comment: Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER. +synonym: "heat shock protein activity" RELATED [] +is_a: GO:0035966 ! response to topologically incorrect protein + +[Term] +id: GO:0006987 +name: obsolete activation of signaling protein activity involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response." [GOC:dph, GOC:mah, GOC:tb, PMID:12042763] +comment: The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498). +synonym: "unfolded protein response, activation of signaling protein activity" EXACT [GOC:dph, GOC:tb] +synonym: "unfolded protein response, activation of signaling protein kinase/endonuclease" EXACT [] +synonym: "unfolded protein response, activation of signalling protein kinase/endonuclease" EXACT [] +is_obsolete: true +consider: GO:0036498 + +[Term] +id: GO:0006988 +name: obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor" EXACT [] +is_obsolete: true +consider: GO:0004521 + +[Term] +id: GO:0006989 +name: obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase" EXACT [] +is_obsolete: true +consider: GO:0008452 + +[Term] +id: GO:0006990 +name: positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response +namespace: biological_process +def: "The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response." [GOC:dph, GOC:mah, GOC:tb, GOC:txnOH, PMID:12042763] +synonym: "positive regulation of transcription of target genes involved in unfolded protein response" EXACT [GOC:dph, GOC:tb] +synonym: "unfolded protein response, activation of target gene transcription" NARROW [] +synonym: "unfolded protein response, positive regulation of target gene transcription" EXACT [GOC:tb] +synonym: "unfolded protein response, stimulation of target gene transcription" NARROW [] +synonym: "unfolded protein response, target gene transcriptional activation" BROAD [] +synonym: "unfolded protein response, up regulation of target gene transcription" EXACT [] +synonym: "unfolded protein response, up-regulation of target gene transcription" EXACT [] +synonym: "unfolded protein response, upregulation of target gene transcription" EXACT [] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0030968 ! endoplasmic reticulum unfolded protein response +relationship: part_of GO:0030968 ! endoplasmic reticulum unfolded protein response + +[Term] +id: GO:0006991 +name: response to sterol depletion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:bf, ISBN:0198506732] +synonym: "sterol depletion response" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0006995 +name: cellular response to nitrogen starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen." [GOC:jl] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0043562 ! cellular response to nitrogen levels + +[Term] +id: GO:0006996 +name: organelle organization +namespace: biological_process +alt_id: GO:1902589 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +synonym: "organelle organisation" EXACT [] +synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah] +synonym: "single organism organelle organization" EXACT [GOC:TermGenie] +synonym: "single-organism organelle organization" RELATED [] +is_a: GO:0016043 ! cellular component organization +created_by: jl +creation_date: 2013-12-19T15:25:51Z + +[Term] +id: GO:0006997 +name: nucleus organization +namespace: biological_process +alt_id: GO:0048287 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_yeast +synonym: "nuclear morphology" RELATED [] +synonym: "nuclear organisation" EXACT [] +synonym: "nuclear organization" EXACT [] +synonym: "nuclear organization and biogenesis" RELATED [GOC:mah] +synonym: "nucleus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0006998 +name: nuclear envelope organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] +synonym: "nuclear envelope organisation" EXACT [GOC:mah] +synonym: "nuclear envelope organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0006997 ! nucleus organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0006999 +name: nuclear pore organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] +synonym: "nuclear pore complex organization and biogenesis" RELATED [GOC:mah] +synonym: "nuclear pore organisation" EXACT [] +synonym: "nuclear pore organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0043933 ! protein-containing complex subunit organization + +[Term] +id: GO:0007000 +name: nucleolus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] +synonym: "nucleolus organisation" EXACT [] +synonym: "nucleolus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006997 ! nucleus organization + +[Term] +id: GO:0007002 +name: obsolete centromere binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "centromere binding" EXACT [] +is_obsolete: true +replaced_by: GO:0019237 + +[Term] +id: GO:0007003 +name: obsolete telomere binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "telomere binding" EXACT [] +is_obsolete: true +replaced_by: GO:0042162 + +[Term] +id: GO:0007004 +name: telomere maintenance via telomerase +namespace: biological_process +def: "The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase." [GOC:elh] +synonym: "telomerase-dependent telomere maintenance" EXACT [] +is_a: GO:0006278 ! RNA-dependent DNA biosynthetic process +is_a: GO:0010833 ! telomere maintenance via telomere lengthening +relationship: has_part GO:0003720 ! telomerase activity +relationship: has_part GO:1905324 ! telomere-telomerase complex assembly + +[Term] +id: GO:0007005 +name: mitochondrion organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." [GOC:dph, GOC:jl, GOC:mah, GOC:sgd_curators, PMID:9786946] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "mitochondria organization" EXACT [GOC:mah] +synonym: "mitochondrion organisation" EXACT [GOC:mah] +synonym: "mitochondrion organization and biogenesis" RELATED [] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0007006 +name: mitochondrial membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "mitochondrial membrane organisation" EXACT [] +synonym: "mitochondrial membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0061024 ! membrane organization +intersection_of: GO:0061024 ! membrane organization +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0007007 +name: inner mitochondrial membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. +synonym: "inner mitochondrial membrane organisation" EXACT [] +synonym: "inner mitochondrial membrane organization and biogenesis" RELATED [GOC:mah] +synonym: "mitochondrial inner membrane organization" EXACT [] +is_a: GO:0007006 ! mitochondrial membrane organization + +[Term] +id: GO:0007008 +name: outer mitochondrial membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +comment: See also the cellular component term 'mitochondrial outer membrane ; GO:0005741'. +synonym: "outer mitochondrial membrane organisation" EXACT [] +synonym: "outer mitochondrial membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007006 ! mitochondrial membrane organization + +[Term] +id: GO:0007009 +name: plasma membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "plasma membrane organisation" EXACT [] +synonym: "plasma membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0007010 +name: cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] +synonym: "cytoskeletal regulator activity" RELATED [] +synonym: "cytoskeleton organisation" EXACT [] +synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0007011 +name: obsolete regulation of cytoskeleton +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton." [GOC:go_curators] +comment: This term was made obsolete because cytoskeleton is neither a process nor a trait, so the term made no sense. +synonym: "regulation of cytoskeleton" EXACT [] +is_obsolete: true +consider: GO:0007010 + +[Term] +id: GO:0007014 +name: actin ubiquitination +namespace: biological_process +def: "The modification of actin by addition of ubiquitin groups." [GOC:mah] +synonym: "indirect flight muscle actin ubiquitination" NARROW [GOC:mah] +is_a: GO:0016567 ! protein ubiquitination +is_a: GO:0030047 ! actin modification + +[Term] +id: GO:0007015 +name: actin filament organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah] +synonym: "actin filament organisation" EXACT [] +synonym: "regulation of actin filament localization" NARROW [] +is_a: GO:0097435 ! supramolecular fiber organization +relationship: part_of GO:0030036 ! actin cytoskeleton organization + +[Term] +id: GO:0007016 +name: obsolete cytoskeletal anchoring at plasma membrane +namespace: biological_process +def: "OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane." [ISBN:0198599323] +comment: This term was obsoleted because it represents a molecular function. +synonym: "cytoskeletal anchoring activity" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19119 xsd:anyURI +is_obsolete: true +consider: GO:0007010 +consider: GO:0106006 + +[Term] +id: GO:0007017 +name: microtubule-based process +namespace: biological_process +def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] +subset: goslim_chembl +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007018 +name: microtubule-based movement +namespace: biological_process +def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] +is_a: GO:0006928 ! movement of cell or subcellular component +is_a: GO:0007017 ! microtubule-based process + +[Term] +id: GO:0007019 +name: microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194] +synonym: "microtubule catastrophe" NARROW [GOC:dph, GOC:tb] +synonym: "microtubule depolymerization during nuclear congression" NARROW [] +synonym: "microtubule disassembly" EXACT [] +synonym: "microtubule shortening" EXACT [] +is_a: GO:0031109 ! microtubule polymerization or depolymerization +is_a: GO:0051261 ! protein depolymerization +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0007020 +name: microtubule nucleation +namespace: biological_process +def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712] +xref: Wikipedia:Microtubule_nucleation +is_a: GO:0000226 ! microtubule cytoskeleton organization +relationship: part_of GO:0046785 ! microtubule polymerization + +[Term] +id: GO:0007021 +name: tubulin complex assembly +namespace: biological_process +def: "The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer." [GOC:mah] +synonym: "tubulin assembly" EXACT [] +synonym: "tubulin folding" RELATED [] +synonym: "tubulin-specific chaperone activity" RELATED [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0007023 +name: post-chaperonin tubulin folding pathway +namespace: biological_process +def: "Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors." [PMID:10542094] +is_a: GO:0006457 ! protein folding + +[Term] +id: GO:0007026 +name: negative regulation of microtubule depolymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] +synonym: "down regulation of microtubule depolymerization" EXACT [] +synonym: "down-regulation of microtubule depolymerization" EXACT [] +synonym: "downregulation of microtubule depolymerization" EXACT [] +synonym: "inhibition of microtubule depolymerization" NARROW [] +synonym: "microtubule rescue" NARROW [GOC:dph, GOC:tb] +synonym: "microtubule stabilization" EXACT [] +synonym: "negative regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] +synonym: "negative regulation of microtubule disassembly" EXACT [] +is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization +is_a: GO:0031114 ! regulation of microtubule depolymerization +is_a: GO:1901880 ! negative regulation of protein depolymerization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007019 ! microtubule depolymerization +relationship: negatively_regulates GO:0007019 ! microtubule depolymerization + +[Term] +id: GO:0007027 +name: negative regulation of axonemal microtubule depolymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] +synonym: "axonemal microtubule stabilization" EXACT [] +synonym: "negative regulation of microtubule depolymerization in axoneme" RELATED [GOC:dph] +is_a: GO:0007026 ! negative regulation of microtubule depolymerization +is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization +relationship: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization + +[Term] +id: GO:0007028 +name: cytoplasm organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "cytoplasm organisation" EXACT [] +synonym: "cytoplasm organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0007029 +name: endoplasmic reticulum organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "endoplasmic reticulum morphology" RELATED [] +synonym: "endoplasmic reticulum organisation" EXACT [] +synonym: "endoplasmic reticulum organization and biogenesis" RELATED [GOC:mah] +synonym: "ER organisation" EXACT [] +synonym: "ER organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0007030 +name: Golgi organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "Golgi organisation" EXACT [] +synonym: "Golgi organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0007031 +name: peroxisome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:mah] +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "peroxisome organisation" EXACT [] +synonym: "peroxisome organization and biogenesis" RELATED [GOC:mah] +synonym: "peroxisome-assembly ATPase activity" RELATED [] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0007032 +name: endosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "endosome organisation" EXACT [] +synonym: "endosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016050 ! vesicle organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0007033 +name: vacuole organization +namespace: biological_process +alt_id: GO:0044086 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] +subset: goslim_pir +subset: goslim_yeast +synonym: "vacuolar assembly" NARROW [GOC:mah] +synonym: "vacuole biogenesis" RELATED [GOC:mah] +synonym: "vacuole organisation" EXACT [] +synonym: "vacuole organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0007034 +name: vacuolar transport +namespace: biological_process +def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai] +subset: goslim_chembl +subset: goslim_generic +is_a: GO:0006810 ! transport +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007035 +name: vacuolar acidification +namespace: biological_process +def: "Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion." [GOC:jid] +is_a: GO:0051452 ! intracellular pH reduction + +[Term] +id: GO:0007036 +name: vacuolar calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings." [GOC:ai, GOC:mah] +is_a: GO:0006874 ! cellular calcium ion homeostasis +intersection_of: GO:0055074 ! calcium ion homeostasis +intersection_of: occurs_in GO:0005773 ! vacuole +relationship: occurs_in GO:0005773 ! vacuole + +[Term] +id: GO:0007038 +name: endocytosed protein transport to vacuole +namespace: biological_process +def: "The directed movement of proteins imported into a cell by endocytosis to the vacuole." [GOC:ai] +comment: See also the biological process term 'endocytosis ; GO:0006897'. +synonym: "delivery of endocytosed proteins to the vacuole" EXACT [] +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0015031 ! protein transport + +[Term] +id: GO:0007039 +name: protein catabolic process in the vacuole +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw] +synonym: "vacuolar protein breakdown" RELATED [] +synonym: "vacuolar protein catabolic process" RELATED [] +synonym: "vacuolar protein catabolism" RELATED [] +synonym: "vacuolar protein degradation" RELATED [] +is_a: GO:0044257 ! cellular protein catabolic process +intersection_of: GO:0030163 ! protein catabolic process +intersection_of: occurs_in GO:0005773 ! vacuole +relationship: occurs_in GO:0005773 ! vacuole + +[Term] +id: GO:0007040 +name: lysosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases." [GOC:mah] +synonym: "lysosome organisation" EXACT [] +synonym: "lysosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0080171 ! lytic vacuole organization + +[Term] +id: GO:0007041 +name: lysosomal transport +namespace: biological_process +def: "The directed movement of substances into, out of or within a lysosome." [GOC:ai] +is_a: GO:0007034 ! vacuolar transport + +[Term] +id: GO:0007042 +name: lysosomal lumen acidification +namespace: biological_process +def: "Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion." [GOC:jid] +synonym: "lysosome pH reduction" EXACT [GOC:bf, GOC:rph] +is_a: GO:0007035 ! vacuolar acidification +is_a: GO:0035751 ! regulation of lysosomal lumen pH + +[Term] +id: GO:0007043 +name: cell-cell junction assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai] +synonym: "intercellular junction assembly" EXACT [] +is_a: GO:0034329 ! cell junction assembly +is_a: GO:0045216 ! cell-cell junction organization + +[Term] +id: GO:0007044 +name: cell-substrate junction assembly +namespace: biological_process +alt_id: GO:0007045 +def: "The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate." [GOC:mah] +comment: The primary label for merged term was 'cell-substrate adherens junction assembly' GO:0007045. The term was merged into the parent 'cell-substrate junction assembly', because, based on the most recent litarature, 'adherens junction' is always a 'cell-cell junction' (PMID:20571587, PMID:17854762, PMID:21422226, PMID:28096264, PMID:28401269, PMID:26923917). +synonym: "cell-substrate adherens junction assembly" RELATED [] +is_a: GO:0034329 ! cell junction assembly +is_a: GO:0150115 ! cell-substrate junction organization + +[Term] +id: GO:0007048 +name: obsolete oncogenesis +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a pathological process. +synonym: "oncogenesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007049 +name: cell cycle +namespace: biological_process +def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle] +subset: gocheck_do_not_manually_annotate +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +synonym: "cell-division cycle" EXACT [] +xref: Wikipedia:Cell_cycle +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007050 +name: cell cycle arrest +namespace: biological_process +def: "A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M)." [GOC:dph, GOC:mah, GOC:tb] +synonym: "arrest of cell cycle progression" EXACT [] +synonym: "cessation of cell cycle" EXACT [] +synonym: "termination of cell cycle" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0045786 ! negative regulation of cell cycle + +[Term] +id: GO:0007051 +name: spindle organization +namespace: biological_process +alt_id: GO:0043146 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart." [GOC:go_curators, GOC:mah] +synonym: "spindle organisation" EXACT [] +synonym: "spindle organization and biogenesis" RELATED [GOC:mah] +synonym: "spindle stabilization" RELATED [] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0007052 +name: mitotic spindle organization +namespace: biological_process +alt_id: GO:0000071 +alt_id: GO:0030472 +alt_id: GO:0043148 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." [GOC:go_curators, GOC:mah] +comment: In fission yeast most mitotic spindle organization occurs in the nucleus. +synonym: "mitotic spindle organisation" EXACT [] +synonym: "mitotic spindle organisation in nucleus" NARROW [] +synonym: "mitotic spindle organization and biogenesis" RELATED [GOC:mah] +synonym: "mitotic spindle organization and biogenesis in cell nucleus" NARROW [] +synonym: "mitotic spindle organization and biogenesis in nucleus" NARROW [] +synonym: "mitotic spindle organization in nucleus" NARROW [] +synonym: "mitotic spindle stabilization" RELATED [] +synonym: "spindle organization and biogenesis during mitosis" EXACT [] +synonym: "spindle organization and biogenesis in nucleus during mitosis" NARROW [] +is_a: GO:0007051 ! spindle organization +is_a: GO:1902850 ! microtubule cytoskeleton organization involved in mitosis +intersection_of: GO:0007051 ! spindle organization +intersection_of: part_of GO:0000278 ! mitotic cell cycle +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15341 xsd:anyURI + +[Term] +id: GO:0007053 +name: spindle assembly involved in male meiosis +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." [GOC:mah] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0090306 ! spindle assembly involved in meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007140 ! male meiotic nuclear division +relationship: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0007054 +name: spindle assembly involved in male meiosis I +namespace: biological_process +def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." [GOC:mah] +synonym: "male meiosis I spindle assembly" RELATED [] +is_a: GO:0007053 ! spindle assembly involved in male meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007141 ! male meiosis I +relationship: part_of GO:0007141 ! male meiosis I + +[Term] +id: GO:0007055 +name: spindle assembly involved in male meiosis II +namespace: biological_process +def: "The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." [GOC:mah] +synonym: "male meiosis II spindle assembly" RELATED [] +is_a: GO:0007053 ! spindle assembly involved in male meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007142 ! male meiosis II +relationship: part_of GO:0007142 ! male meiosis II + +[Term] +id: GO:0007056 +name: spindle assembly involved in female meiosis +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." [GOC:mah] +synonym: "female meiotic spindle assembly" RELATED [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0090306 ! spindle assembly involved in meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007143 ! female meiotic nuclear division +relationship: part_of GO:0007143 ! female meiotic nuclear division + +[Term] +id: GO:0007057 +name: spindle assembly involved in female meiosis I +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." [GOC:mah] +synonym: "female meiosis I spindle assembly" RELATED [] +is_a: GO:0007056 ! spindle assembly involved in female meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007144 ! female meiosis I +relationship: part_of GO:0007144 ! female meiosis I + +[Term] +id: GO:0007058 +name: spindle assembly involved in female meiosis II +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." [GOC:mah] +synonym: "female meiosis II spindle assembly" RELATED [] +is_a: GO:0007056 ! spindle assembly involved in female meiosis +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0007147 ! female meiosis II +relationship: part_of GO:0007147 ! female meiosis II + +[Term] +id: GO:0007059 +name: chromosome segregation +namespace: biological_process +def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_yeast +synonym: "chromosome division" EXACT [] +synonym: "chromosome transmission" RELATED [] +xref: Wikipedia:Chromosome_segregation +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007060 +name: male meiosis chromosome segregation +namespace: biological_process +def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." [GOC:ai] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045132 ! meiotic chromosome segregation +relationship: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0007062 +name: sister chromatid cohesion +namespace: biological_process +def: "The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other." [GOC:jh, GOC:mah, ISBN:0815316194] +synonym: "coheson-mediated DNA tethering" EXACT [] +synonym: "sister chromatid alignment" RELATED [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0051276 ! chromosome organization +relationship: part_of GO:0000819 ! sister chromatid segregation + +[Term] +id: GO:0007063 +name: regulation of sister chromatid cohesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] +is_a: GO:0033045 ! regulation of sister chromatid segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007062 ! sister chromatid cohesion +relationship: regulates GO:0007062 ! sister chromatid cohesion + +[Term] +id: GO:0007064 +name: mitotic sister chromatid cohesion +namespace: biological_process +def: "The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission." [GOC:ai, GOC:rn, PMID:10827941, PMID:11389843, PMID:14623866] +is_a: GO:0007062 ! sister chromatid cohesion +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0007062 ! sister chromatid cohesion +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0007065 +name: male meiosis sister chromatid cohesion +namespace: biological_process +def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male." [GOC:ai] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051177 ! meiotic sister chromatid cohesion +relationship: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0007066 +name: female meiosis sister chromatid cohesion +namespace: biological_process +def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female." [GOC:ai] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051177 ! meiotic sister chromatid cohesion +relationship: part_of GO:0007143 ! female meiotic nuclear division + +[Term] +id: GO:0007068 +name: obsolete negative regulation of transcription during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "down regulation of transcription during mitosis" EXACT [GOC:mah] +synonym: "down-regulation of transcription during mitosis" EXACT [GOC:mah] +synonym: "downregulation of transcription during mitosis" EXACT [GOC:mah] +synonym: "inhibition of transcription during mitosis" NARROW [GOC:mah] +synonym: "mitotic repression of transcription" EXACT [] +synonym: "negative regulation of transcription, mitotic" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0007069 +name: obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "down regulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +synonym: "down-regulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +synonym: "downregulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +synonym: "inhibition of transcription from RNA polymerase I promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic repression of transcription from Pol I promoter" EXACT [] +synonym: "negative regulation of transcription from Pol I promoter during mitosis" EXACT [GOC:mah] +synonym: "negative regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0007070 +name: obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "down regulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +synonym: "down-regulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +synonym: "downregulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +synonym: "inhibition of transcription from RNA polymerase II promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic repression of transcription from Pol II promoter" EXACT [] +synonym: "negative regulation of transcription from Pol II promoter during mitosis" EXACT [GOC:mah] +synonym: "negative regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0007071 +name: obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "down regulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +synonym: "down-regulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +synonym: "downregulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +synonym: "inhibition of transcription from RNA polymerase III promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic repression of transcription from Pol III promoter" EXACT [] +synonym: "negative regulation of transcription from Pol III promoter during mitosis" EXACT [GOC:mah] +synonym: "negative regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0007072 +name: positive regulation of transcription involved in exit from mitosis +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:isa_complete, GOC:tb] +synonym: "activation of transcription on exit from mitosis" NARROW [GOC:dph, GOC:tb] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: part_of GO:0010458 ! exit from mitosis +relationship: part_of GO:0010458 ! exit from mitosis + +[Term] +id: GO:0007073 +name: positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] +synonym: "activation of transcription on exit from mitosis, from Pol I promoter" NARROW [GOC:dph, GOC:tb] +synonym: "activation of transcription on exit from mitosis, from RNA polymerase I promoter" NARROW [] +is_a: GO:0007072 ! positive regulation of transcription involved in exit from mitosis + +[Term] +id: GO:0007074 +name: positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] +synonym: "activation of transcription on exit from mitosis, from Pol II promoter" NARROW [] +synonym: "activation of transcription on exit from mitosis, from RNA polymerase II promoter" NARROW [] +is_a: GO:0007072 ! positive regulation of transcription involved in exit from mitosis + +[Term] +id: GO:0007075 +name: positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] +synonym: "activation of transcription on exit from mitosis, from Pol III promoter" NARROW [] +synonym: "activation of transcription on exit from mitosis, from RNA polymerase III promoter" NARROW [GOC:dph, GOC:tb] +is_a: GO:0007072 ! positive regulation of transcription involved in exit from mitosis + +[Term] +id: GO:0007076 +name: mitotic chromosome condensation +namespace: biological_process +def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] +is_a: GO:0030261 ! chromosome condensation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0030261 ! chromosome condensation +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0007077 +name: mitotic nuclear envelope disassembly +namespace: biological_process +def: "The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs." [GOC:bf] +synonym: "mitotic nuclear envelope breakdown" EXACT [] +synonym: "mitotic nuclear envelope catabolism" EXACT [] +synonym: "mitotic nuclear envelope degradation" EXACT [] +is_a: GO:0051081 ! nuclear envelope disassembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051081 ! nuclear envelope disassembly +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007078 +name: lamin depolymerization +namespace: biological_process +def: "The cell cycle process in which lamin is depolymerized." [GOC:jid] +is_a: GO:0051261 ! protein depolymerization +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007077 ! mitotic nuclear envelope disassembly + +[Term] +id: GO:0007079 +name: mitotic chromosome movement towards spindle pole +namespace: biological_process +alt_id: GO:0007082 +def: "The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis." [GOC:ai] +synonym: "chromosome migration to spindle pole during mitosis" EXACT [] +synonym: "chromosome movement towards spindle pole during mitosis" EXACT [] +synonym: "mitotic chromosome movement" BROAD [] +synonym: "mitotic chromosome movement to spindle pole" EXACT [] +synonym: "mitotic sister chromosome movement towards spindle pole" EXACT [] +synonym: "sister chromosome movement towards spindle pole during mitosis" EXACT [] +is_a: GO:0051305 ! chromosome movement towards spindle pole +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051305 ! chromosome movement towards spindle pole +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0007080 +name: mitotic metaphase plate congression +namespace: biological_process +def: "The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis." [GOC:mah, ISBN:0815316194] +is_a: GO:0051310 ! metaphase plate congression +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051310 ! metaphase plate congression +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0007081 +name: obsolete mitotic sister-chromatid adhesion release +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the term name is ambiguous and appears to encompass two processes. +synonym: "mitotic sister-chromatid adhesion release" EXACT [] +is_obsolete: true +consider: GO:0000070 +consider: GO:0007064 + +[Term] +id: GO:0007083 +name: mitotic chromosome decondensation +namespace: biological_process +def: "The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells." [GOC:ai] +is_a: GO:0051312 ! chromosome decondensation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051312 ! chromosome decondensation +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0007084 +name: mitotic nuclear envelope reassembly +namespace: biological_process +def: "The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division." [GOC:ai] +is_a: GO:0031468 ! nuclear envelope reassembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0031468 ! nuclear envelope reassembly +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007085 +name: obsolete nuclear membrane vesicle binding to chromatin +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a molecular function. +synonym: "nuclear membrane vesicle binding to chromatin" EXACT [] +is_obsolete: true +consider: GO:0003682 + +[Term] +id: GO:0007086 +name: vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly +namespace: biological_process +def: "The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly." [GOC:jid, GOC:mah] +is_a: GO:0000740 ! nuclear membrane fusion +is_a: GO:0006906 ! vesicle fusion +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007084 ! mitotic nuclear envelope reassembly +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007087 +name: mitotic nuclear pore complex reassembly +namespace: biological_process +def: "The cell cycle process in which nuclear pore complexes reform during mitotic cell division." [GOC:ai] +is_a: GO:0051292 ! nuclear pore complex assembly +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007084 ! mitotic nuclear envelope reassembly + +[Term] +id: GO:0007088 +name: regulation of mitotic nuclear division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] +synonym: "regulation of mitosis" EXACT [] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051783 ! regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0140014 ! mitotic nuclear division +relationship: regulates GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0007089 +name: traversing start control point of mitotic cell cycle +namespace: biological_process +alt_id: GO:0000081 +def: "A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity." [GOC:mtg_cell_cycle] +is_a: GO:1900087 ! positive regulation of G1/S transition of mitotic cell cycle + +[Term] +id: GO:0007090 +name: obsolete regulation of S phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle." [GOC:go_curators] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "regulation of S-phase of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0044772 + +[Term] +id: GO:0007091 +name: metaphase/anaphase transition of mitotic cell cycle +namespace: biological_process +def: "The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." [GOC:mtg_cell_cycle, PMID:10465783] +synonym: "metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [GOC:vw] +synonym: "mitotic metaphase/anaphase transition" EXACT [] +is_a: GO:0010965 ! regulation of mitotic sister chromatid separation +is_a: GO:0044772 ! mitotic cell cycle phase transition +is_a: GO:0044784 ! metaphase/anaphase transition of cell cycle +intersection_of: GO:0044784 ! metaphase/anaphase transition of cell cycle +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007093 +name: mitotic cell cycle checkpoint +namespace: biological_process +alt_id: GO:0031575 +alt_id: GO:0071780 +def: "A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage." [GOC:mtg_cell_cycle] +synonym: "mitotic checkpoint" RELATED [] +is_a: GO:0000075 ! cell cycle checkpoint +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0000075 ! cell cycle checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007094 +name: mitotic spindle assembly checkpoint +namespace: biological_process +alt_id: GO:0044810 +def: "A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mtg_cell_cycle, PMID:12360190] +synonym: "Dma1-dependent checkpoint" NARROW [] +synonym: "Mad2-dependent checkpoint" NARROW [] +synonym: "mitotic cell cycle spindle assembly checkpoint" EXACT [] +synonym: "SAC-independent checkpoint" NARROW [] +is_a: GO:0045841 ! negative regulation of mitotic metaphase/anaphase transition +is_a: GO:0071173 ! spindle assembly checkpoint +is_a: GO:0071174 ! mitotic spindle checkpoint +intersection_of: GO:0071173 ! spindle assembly checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007095 +name: mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G2/M transition DNA damage checkpoint" EXACT [] +is_a: GO:0031572 ! G2 DNA damage checkpoint +is_a: GO:0044773 ! mitotic DNA damage checkpoint +is_a: GO:0044818 ! mitotic G2/M transition checkpoint +intersection_of: GO:0031572 ! G2 DNA damage checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007096 +name: regulation of exit from mitosis +namespace: biological_process +def: "Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity." [GOC:rn] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010458 ! exit from mitosis +relationship: regulates GO:0010458 ! exit from mitosis + +[Term] +id: GO:0007097 +name: nuclear migration +namespace: biological_process +alt_id: GO:0040023 +def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai] +subset: goslim_aspergillus +synonym: "establishment of cell nucleus localization" RELATED [] +synonym: "establishment of localization of nucleus" RELATED [] +synonym: "establishment of nucleus localisation" RELATED [GOC:mah] +synonym: "establishment of nucleus localization" RELATED [] +synonym: "establishment of position of nucleus" EXACT [] +synonym: "nuclear movement" EXACT [] +synonym: "nuclear positioning" EXACT [] +synonym: "nucleus migration" EXACT [] +synonym: "nucleus positioning" EXACT [] +synonym: "positioning of nucleus" EXACT [] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0051647 ! nucleus localization +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0007098 +name: centrosome cycle +namespace: biological_process +alt_id: GO:0051297 +def: "The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." [ISBN:0815316194] +synonym: "centrosome organisation" EXACT [] +synonym: "centrosome organization" EXACT [] +synonym: "centrosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0031023 ! microtubule organizing center organization +property_value: RO:0002161 NCBITaxon:27896 +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007099 +name: centriole replication +namespace: biological_process +alt_id: GO:0032054 +def: "The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0." [GOC:cilia, GOC:kmv, ISBN:0815316194, PMID:9889124] +synonym: "centriole duplication" EXACT [] +synonym: "ciliary basal body duplication" RELATED [] +synonym: "microtubule basal body duplication" BROAD [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0098534 ! centriole assembly +relationship: part_of GO:0051298 ! centrosome duplication + +[Term] +id: GO:0007100 +name: mitotic centrosome separation +namespace: biological_process +def: "Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [ISBN:0815316194] +is_a: GO:0051299 ! centrosome separation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051299 ! centrosome separation +intersection_of: part_of GO:0140014 ! mitotic nuclear division +relationship: part_of GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0007101 +name: obsolete male meiosis centrosome cycle +namespace: biological_process +def: "OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism." [GOC:mah] +comment: false +synonym: "centrosome cycle involved in male meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_obsolete: true + +[Term] +id: GO:0007105 +name: cytokinesis, site selection +namespace: biological_process +alt_id: GO:0010687 +def: "The process of marking the place where cytokinesis will occur." [GOC:mtg_cell_cycle] +synonym: "site selection involved in cell cycle cytokinesis" EXACT [] +synonym: "site selection involved in cytokinesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032506 ! cytokinetic process + +[Term] +id: GO:0007106 +name: obsolete cytokinesis, protein recruitment +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was not defined. +synonym: "cytokinesis, protein recruitment" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007107 +name: membrane addition at site of cytokinesis +namespace: biological_process +def: "Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion." [GOC:clt] +synonym: "cytokinesis, membrane recruitment/generation" EXACT [] +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0061024 ! membrane organization + +[Term] +id: GO:0007108 +name: obsolete cytokinesis, initiation of separation +namespace: biological_process +def: "OBSOLETE. The process involved in starting cell separation." [GOC:clt, GOC:dph, GOC:tb] +comment: This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate. +synonym: "cytokinesis, initiation of separation" EXACT [] +synonym: "initiation of separation involved in cytokinesis" EXACT [GOC:dph, GOC:tb] +is_obsolete: true + +[Term] +id: GO:0007109 +name: obsolete cytokinesis, completion of separation +namespace: biological_process +def: "OBSOLETE. The process of finishing cell separation, which results in two physically separated cells." [GOC:clt, GOC:dph, GOC:tb] +comment: This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate. +synonym: "completion of separation involved in cytokinesis" EXACT [GOC:dph, GOC:tb] +synonym: "cytokinesis, completion of separation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007110 +name: meiosis I cytokinesis +namespace: biological_process +def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells." [GOC:mtg_cell_cycle] +synonym: "cytokinesis after meiosis I" EXACT [] +is_a: GO:0033206 ! meiotic cytokinesis +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0007111 +name: meiosis II cytokinesis +namespace: biological_process +def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells." [GOC:mtg_cell_cycle] +synonym: "cytokinesis after meiosis II" EXACT [] +is_a: GO:0033206 ! meiotic cytokinesis +is_a: GO:0061983 ! meiosis II cell cycle process + +[Term] +id: GO:0007112 +name: male meiosis cytokinesis +namespace: biological_process +def: "A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells." [GOC:ai] +synonym: "cytokinesis after male meiosis" EXACT [GOC:dph, GOC:tb] +synonym: "cytokinesis involved in male meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0033206 ! meiotic cytokinesis +intersection_of: GO:0000910 ! cytokinesis +intersection_of: part_of GO:0007140 ! male meiotic nuclear division +relationship: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0007113 +name: endomitotic cell cycle +namespace: biological_process +def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm] +comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins. +synonym: "endomitosis" RELATED [] +xref: Wikipedia:Mitosis#Endomitosis +is_a: GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007114 +name: cell budding +namespace: biological_process +def: "A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell." [ISBN:0198506732] +subset: goslim_candida +subset: goslim_yeast +synonym: "budding" BROAD [] +is_a: GO:0019954 ! asexual reproduction +is_a: GO:0032505 ! reproduction of a single-celled organism +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0007115 +name: obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents two processes. +synonym: "bud site selection/establishment of cell polarity (sensu Saccharomyces)" EXACT [] +is_obsolete: true +consider: GO:0000282 +consider: GO:0030010 + +[Term] +id: GO:0007116 +name: regulation of cell budding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation and growth of cell buds." [GOC:mah] +synonym: "regulation of budding" BROAD [] +is_a: GO:0051302 ! regulation of cell division +is_a: GO:1903664 ! regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007114 ! cell budding +relationship: regulates GO:0007114 ! cell budding + +[Term] +id: GO:0007117 +name: budding cell bud growth +namespace: biological_process +def: "The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:go_curators] +synonym: "bud growth" BROAD [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0040007 ! growth +relationship: part_of GO:0007114 ! cell budding + +[Term] +id: GO:0007118 +name: budding cell apical bud growth +namespace: biological_process +def: "Growth at the tip of a bud, in a cell that reproduces by budding." [GOC:go_curators] +synonym: "apical bud growth" BROAD [] +is_a: GO:0007117 ! budding cell bud growth + +[Term] +id: GO:0007119 +name: budding cell isotropic bud growth +namespace: biological_process +def: "Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding." [GOC:go_curators] +synonym: "isotropic bud growth" BROAD [] +is_a: GO:0007117 ! budding cell bud growth + +[Term] +id: GO:0007120 +name: axial cellular bud site selection +namespace: biological_process +def: "The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell." [GOC:clt] +synonym: "axial bud site selection" EXACT [] +synonym: "axial budding" BROAD [] +is_a: GO:0000282 ! cellular bud site selection +is_a: GO:0007114 ! cell budding + +[Term] +id: GO:0007121 +name: bipolar cellular bud site selection +namespace: biological_process +def: "The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell." [GOC:clt] +synonym: "bipolar bud site selection" EXACT [] +synonym: "bipolar budding" BROAD [] +synonym: "polar budding" BROAD [] +is_a: GO:0000282 ! cellular bud site selection +is_a: GO:0007114 ! cell budding + +[Term] +id: GO:0007122 +name: obsolete loss of asymmetric budding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it is a phenotype rather than a biological process. +synonym: "loss of asymmetric budding" EXACT [] +is_obsolete: true +consider: GO:0006033 + +[Term] +id: GO:0007123 +name: obsolete bud scar accumulation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it is a phenotype rather than a biological process. +synonym: "bud scar accumulation" EXACT [] +is_obsolete: true +consider: GO:0000282 + +[Term] +id: GO:0007124 +name: pseudohyphal growth +namespace: biological_process +def: "A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate." [GOC:krc, PMID:11104818] +subset: goslim_candida +subset: goslim_yeast +is_a: GO:0016049 ! cell growth +is_a: GO:0070783 ! growth of unicellular organism as a thread of attached cells + +[Term] +id: GO:0007125 +name: obsolete invasive growth +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it has been split into two new terms. +synonym: "invasive growth" EXACT [] +is_obsolete: true +consider: GO:0001403 +consider: GO:0044409 + +[Term] +id: GO:0007127 +name: meiosis I +namespace: biological_process +def: "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." [GOC:dph, GOC:jl, GOC:mtg_cell_cycle, PMID:9334324] +synonym: "meiosis I nuclear division" EXACT [] +xref: Wikipedia:Meiosis#Meiosis_I +is_a: GO:0061982 ! meiosis I cell cycle process +is_a: GO:0140013 ! meiotic nuclear division +relationship: ends_during GO:0007134 ! meiotic telophase I + +[Term] +id: GO:0007128 +name: meiotic prophase I +namespace: biological_process +def: "The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051324 ! prophase +is_a: GO:0098764 ! meiosis I cell cycle phase + +[Term] +id: GO:0007129 +name: synapsis +namespace: biological_process +def: "The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Synapsis begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete." [GOC:mtg_cell_cycle, PMID:22582262, PMID:23117617] +synonym: "chromosomal pairing" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "chromosomal synapsis" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "homologous chromosome pairing at meiosis" EXACT [] +xref: Wikipedia:Synapsis +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +relationship: part_of GO:0045143 ! homologous chromosome segregation + +[Term] +id: GO:0007130 +name: synaptonemal complex assembly +namespace: biological_process +def: "The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination." [ISBN:0198506732] +synonym: "synaptonemal complex formation" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +is_a: GO:0070193 ! synaptonemal complex organization +relationship: part_of GO:0007129 ! synapsis + +[Term] +id: GO:0007131 +name: reciprocal meiotic recombination +namespace: biological_process +alt_id: GO:0000021 +alt_id: GO:0007145 +def: "The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity." [PMID:2087779] +synonym: "female meiotic recombination" NARROW [] +synonym: "gene conversion with reciprocal crossover" EXACT [] +is_a: GO:0035825 ! homologous recombination +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0007132 +name: meiotic metaphase I +namespace: biological_process +def: "The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051323 ! metaphase +is_a: GO:0098764 ! meiosis I cell cycle phase + +[Term] +id: GO:0007133 +name: meiotic anaphase I +namespace: biological_process +def: "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051322 ! anaphase +is_a: GO:0098764 ! meiosis I cell cycle phase + +[Term] +id: GO:0007134 +name: meiotic telophase I +namespace: biological_process +def: "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051326 ! telophase +is_a: GO:0098764 ! meiosis I cell cycle phase + +[Term] +id: GO:0007135 +name: meiosis II +namespace: biological_process +def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684] +synonym: "meiosis II nuclear division" EXACT [] +xref: Wikipedia:Meiosis#Meiosis_II +is_a: GO:0061983 ! meiosis II cell cycle process +is_a: GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0007136 +name: meiotic prophase II +namespace: biological_process +def: "The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051324 ! prophase +is_a: GO:0098765 ! meiosis II cell cycle phase + +[Term] +id: GO:0007137 +name: meiotic metaphase II +namespace: biological_process +def: "The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051323 ! metaphase +is_a: GO:0098765 ! meiosis II cell cycle phase + +[Term] +id: GO:0007138 +name: meiotic anaphase II +namespace: biological_process +def: "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051322 ! anaphase +is_a: GO:0098765 ! meiosis II cell cycle phase + +[Term] +id: GO:0007139 +name: meiotic telophase II +namespace: biological_process +def: "The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051326 ! telophase +is_a: GO:0098765 ! meiosis II cell cycle phase + +[Term] +id: GO:0007140 +name: male meiotic nuclear division +namespace: biological_process +def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw] +synonym: "male meiosis" RELATED [] +synonym: "male nuclear division" BROAD [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0140013 ! meiotic nuclear division +intersection_of: GO:0000280 ! nuclear division +intersection_of: part_of GO:0048232 ! male gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0048232 ! male gamete generation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007141 +name: male meiosis I +namespace: biological_process +def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline." [GOC:dph, GOC:mah] +synonym: "male meiosis I nuclear division" EXACT [] +is_a: GO:0007127 ! meiosis I +is_a: GO:0007140 ! male meiotic nuclear division +intersection_of: GO:0007127 ! meiosis I +intersection_of: part_of GO:0048232 ! male gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0007142 +name: male meiosis II +namespace: biological_process +def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah] +synonym: "male meiosis II nuclear division" EXACT [] +is_a: GO:0007135 ! meiosis II +is_a: GO:0007140 ! male meiotic nuclear division +intersection_of: GO:0007135 ! meiosis II +intersection_of: part_of GO:0048232 ! male gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0007143 +name: female meiotic nuclear division +namespace: biological_process +def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw] +comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'. +synonym: "female meiosis" BROAD [] +synonym: "female meiotic division" BROAD [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0140013 ! meiotic nuclear division +intersection_of: GO:0000280 ! nuclear division +intersection_of: part_of GO:0007292 ! female gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0007292 ! female gamete generation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007144 +name: female meiosis I +namespace: biological_process +def: "The cell cycle process in which the first meiotic division occurs in the female germline." [GOC:mah] +synonym: "female meiosis I nuclear division" EXACT [] +is_a: GO:0007127 ! meiosis I +is_a: GO:0007143 ! female meiotic nuclear division +intersection_of: GO:0007127 ! meiosis I +intersection_of: part_of GO:0007292 ! female gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0007146 +name: meiotic recombination nodule assembly +namespace: biological_process +def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes." [GOC:jl, PMID:9334324] +is_a: GO:0000707 ! meiotic DNA recombinase assembly + +[Term] +id: GO:0007147 +name: female meiosis II +namespace: biological_process +def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah] +synonym: "female meiosis II nuclear division" EXACT [] +is_a: GO:0007135 ! meiosis II +is_a: GO:0007143 ! female meiotic nuclear division +intersection_of: GO:0007135 ! meiosis II +intersection_of: part_of GO:0007292 ! female gamete generation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0007149 +name: obsolete colony morphology +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it describes a phenotype rather than a biological goal. +synonym: "colony morphology" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007150 +name: obsolete growth pattern +namespace: biological_process +def: "OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances." [GOC:jid] +comment: This term was made obsolete because the original meaning of the term is unclear, the current definition is incorrect, and it does not describe a biological process. +synonym: "growth pattern" EXACT [] +is_obsolete: true +consider: GO:0040007 + +[Term] +id: GO:0007154 +name: cell communication +namespace: biological_process +def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] +subset: goslim_pir +subset: goslim_plant +xref: Wikipedia:Cell_signaling +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007155 +name: cell adhesion +namespace: biological_process +alt_id: GO:0098602 +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_pombe +synonym: "cell adhesion molecule activity" RELATED [] +synonym: "single organism cell adhesion" RELATED [] +xref: Wikipedia:Cell_adhesion +is_a: GO:0009987 ! cellular process +is_a: GO:0022610 ! biological adhesion +created_by: dos +creation_date: 2014-04-15T15:59:10Z + +[Term] +id: GO:0007156 +name: homophilic cell adhesion via plasma membrane adhesion molecules +namespace: biological_process +def: "The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell." [ISBN:0198506732] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules + +[Term] +id: GO:0007157 +name: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules +namespace: biological_process +def: "The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell." [ISBN:0198506732] +synonym: "agglutination" RELATED [GOC:mah] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules + +[Term] +id: GO:0007158 +name: neuron cell-cell adhesion +namespace: biological_process +def: "The attachment of a neuron to another cell via adhesion molecules." [GOC:go_curators] +synonym: "neuron adhesion" EXACT [] +synonym: "neuronal cell adhesion" EXACT [] +is_a: GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0007159 +name: leukocyte cell-cell adhesion +namespace: biological_process +def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators] +synonym: "leukocyte adhesion" EXACT [] +synonym: "leukocyte cell adhesion" EXACT [] +is_a: GO:0098609 ! cell-cell adhesion +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 + +[Term] +id: GO:0007160 +name: cell-matrix adhesion +namespace: biological_process +def: "The binding of a cell to the extracellular matrix via adhesion molecules." [GOC:hb] +is_a: GO:0031589 ! cell-substrate adhesion + +[Term] +id: GO:0007161 +name: calcium-independent cell-matrix adhesion +namespace: biological_process +def: "The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction." [GOC:hb] +synonym: "calcium-independent cell adhesion molecule activity" RELATED [] +is_a: GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0007162 +name: negative regulation of cell adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] +synonym: "cell adhesion receptor inhibitor activity" RELATED [] +synonym: "down regulation of cell adhesion" EXACT [] +synonym: "down-regulation of cell adhesion" EXACT [] +synonym: "downregulation of cell adhesion" EXACT [] +synonym: "inhibition of cell adhesion" NARROW [] +is_a: GO:0030155 ! regulation of cell adhesion +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007155 ! cell adhesion +relationship: negatively_regulates GO:0007155 ! cell adhesion + +[Term] +id: GO:0007163 +name: establishment or maintenance of cell polarity +namespace: biological_process +alt_id: GO:0030012 +alt_id: GO:0030467 +def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] +subset: goslim_pombe +synonym: "cell polarity" RELATED [GOC:mah, GOC:vw] +synonym: "establishment and/or maintenance of cell polarity" RELATED [] +synonym: "establishment and/or maintenance of cell polarization" RELATED [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0007164 +name: establishment of tissue polarity +namespace: biological_process +def: "Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates." [GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007165 +name: signal transduction +namespace: biological_process +alt_id: GO:0023033 +def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] +comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_plant +synonym: "signaling cascade" NARROW [] +synonym: "signaling pathway" RELATED [] +synonym: "signalling cascade" NARROW [] +synonym: "signalling pathway" RELATED [GOC:mah] +xref: Wikipedia:Signal_transduction +is_a: GO:0009987 ! cellular process +is_a: GO:0050794 ! regulation of cellular process +relationship: part_of GO:0007154 ! cell communication +relationship: part_of GO:0023052 ! signaling +relationship: part_of GO:0051716 ! cellular response to stimulus + +[Term] +id: GO:0007166 +name: cell surface receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] +subset: goslim_drosophila +synonym: "cell surface receptor linked signal transduction" EXACT [] +synonym: "cell surface receptor linked signaling pathway" EXACT [GOC:bf] +synonym: "cell surface receptor linked signalling pathway" EXACT [GOC:mah] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0007167 +name: enzyme linked receptor protein signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, ISBN:0815316194] +synonym: "enzyme linked receptor protein signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0007168 +name: receptor guanylyl cyclase signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:16815030] +synonym: "receptor guanylyl cyclase signalling pathway" EXACT [] +is_a: GO:0007167 ! enzyme linked receptor protein signaling pathway + +[Term] +id: GO:0007169 +name: transmembrane receptor protein tyrosine kinase signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, GOC:signaling] +synonym: "transmembrane receptor protein tyrosine kinase signalling pathway" EXACT [] +is_a: GO:0007167 ! enzyme linked receptor protein signaling pathway + +[Term] +id: GO:0007170 +name: obsolete transmembrane receptor protein tyrosine kinase ligand binding +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "transmembrane receptor protein tyrosine kinase ligand binding" EXACT [] +is_obsolete: true +consider: GO:0030971 + +[Term] +id: GO:0007171 +name: activation of transmembrane receptor protein tyrosine kinase activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity." [GOC:dph, GOC:tb] +synonym: "transmembrane receptor protein tyrosine kinase activation" RELATED [GOC:dph, GOC:tb] +synonym: "transmembrane receptor protein tyrosine kinase dimerization" RELATED [GOC:dph, GOC:mtg_lung] +is_a: GO:0032147 ! activation of protein kinase activity +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0007172 +name: signal complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell." [GOC:bf, GOC:signaling, PMID:9646862] +synonym: "signal complex formation" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0007173 +name: epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, PR:000006933] +synonym: "EGF receptor signaling pathway" EXACT [] +synonym: "EGF receptor signalling pathway" EXACT [] +synonym: "EGFR signaling pathway" EXACT [] +synonym: "epidermal growth factor receptor signalling pathway" EXACT [] +synonym: "ERBB1 signaling pathway" EXACT [PR:000006933] +synonym: "receptor tyrosine-protein kinase erbB-1 signaling pathway" EXACT [PR:000006933] +is_a: GO:0038127 ! ERBB signaling pathway + +[Term] +id: GO:0007174 +name: epidermal growth factor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor." [GOC:bf, GOC:signaling, PMID:2985587] +comment: This term describes the breakdown of epidermal growth factor within the cell, following internalization. For proteolysis events that result in the maturation of an epidermal growth factor receptor ligand, see 'epidermal growth factor receptor ligand maturation ; GO:'. +synonym: "EGF breakdown" EXACT [GOC:bf] +synonym: "EGF catabolism" EXACT [GOC:bf] +synonym: "EGF receptor ligand processing" RELATED [GOC:bf] +synonym: "epidermal growth factor breakdown" EXACT [GOC:bf] +synonym: "epidermal growth factor catabolism" EXACT [GOC:bf] +synonym: "epidermal growth factor ligand processing" RELATED [GOC:bf] +synonym: "intracellular EGF processing" RELATED [PMID:2985587] +synonym: "receptor-mediated EGF processing" RELATED [PMID:1683723] +is_a: GO:0042059 ! negative regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0007175 +name: negative regulation of epidermal growth factor-activated receptor activity +namespace: biological_process +alt_id: GO:0007177 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity." [GOC:go_curators] +synonym: "down regulation of epidermal growth factor receptor activity" EXACT [] +synonym: "down-regulation of epidermal growth factor receptor activity" EXACT [] +synonym: "downregulation of epidermal growth factor receptor activity" EXACT [] +synonym: "EGF receptor downregulation" EXACT [] +synonym: "inhibition of epidermal growth factor receptor activity" NARROW [] +synonym: "negative regulation of EGF receptor activity" EXACT [] +synonym: "negative regulation of EGFR activity" EXACT [] +synonym: "negative regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0007176 ! regulation of epidermal growth factor-activated receptor activity +is_a: GO:0042059 ! negative regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0061099 ! negative regulation of protein tyrosine kinase activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005006 ! epidermal growth factor-activated receptor activity +relationship: negatively_regulates GO:0005006 ! epidermal growth factor-activated receptor activity + +[Term] +id: GO:0007176 +name: regulation of epidermal growth factor-activated receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of EGF-activated receptor activity." [GOC:dph, GOC:go_curators] +synonym: "regulation of EGF receptor activity" EXACT [] +synonym: "regulation of EGFR activity" EXACT [] +synonym: "regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0042058 ! regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0061097 ! regulation of protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005006 ! epidermal growth factor-activated receptor activity +relationship: regulates GO:0005006 ! epidermal growth factor-activated receptor activity + +[Term] +id: GO:0007178 +name: transmembrane receptor protein serine/threonine kinase signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] +synonym: "transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [] +is_a: GO:0007167 ! enzyme linked receptor protein signaling pathway + +[Term] +id: GO:0007179 +name: transforming growth factor beta receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mah, GOC:signaling] +synonym: "TGF-beta receptor signaling pathway" EXACT [] +synonym: "TGF-beta receptor signalling pathway" EXACT [] +synonym: "TGFbeta receptor signaling pathway" EXACT [] +synonym: "TGFbeta receptor signalling pathway" EXACT [] +synonym: "transforming growth factor beta receptor signalling pathway" EXACT [] +is_a: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +relationship: part_of GO:0071560 ! cellular response to transforming growth factor beta stimulus + +[Term] +id: GO:0007180 +name: obsolete transforming growth factor beta ligand binding to type II receptor +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a function. +synonym: "TGF-beta ligand binding to type II receptor" EXACT [] +synonym: "TGFbeta ligand binding to type II receptor" EXACT [] +synonym: "transforming growth factor beta ligand binding to type II receptor" EXACT [] +is_obsolete: true +consider: GO:0005026 +consider: GO:0005160 +consider: GO:0050431 + +[Term] +id: GO:0007181 +name: transforming growth factor beta receptor complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex." [GOC:jl, Reactome:R-HSA-170840, Wikipedia:TGF_beta_signaling_pathway] +synonym: "TGF-beta receptor complex assembly" EXACT [] +synonym: "TGF-beta:type II receptor:type I receptor complex assembly" EXACT [] +synonym: "TGFbeta receptor complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007179 ! transforming growth factor beta receptor signaling pathway + +[Term] +id: GO:0007182 +name: common-partner SMAD protein phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus." [GOC:dph, ISBN:3527303782] +synonym: "co-SMAD protein phosphorylation" EXACT [GOC:rl] +synonym: "common mediator SMAD protein phosphorylation" EXACT [] +synonym: "common partner SMAD protein phosphorylation" EXACT [GOC:rl] +synonym: "common-mediator SMAD protein phosphorylation" EXACT [GOC:rl] +is_a: GO:0006468 ! protein phosphorylation +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007183 +name: SMAD protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins." [GOC:isa_complete] +synonym: "SMAD protein heteromerization" NARROW [GOC:mah, PMID:9670020] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway + +[Term] +id: GO:0007185 +name: transmembrane receptor protein tyrosine phosphatase signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] +synonym: "transmembrane receptor protein tyrosine phosphatase signalling pathway" EXACT [] +is_a: GO:0007167 ! enzyme linked receptor protein signaling pathway + +[Term] +id: GO:0007186 +name: G protein-coupled receptor signaling pathway +namespace: biological_process +alt_id: GO:0038042 +def: "A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor] +subset: goslim_drosophila +synonym: "dimeric G-protein coupled receptor signaling pathway" NARROW [] +synonym: "dimeric G-protein coupled receptor signalling pathway" NARROW [GOC:mah] +synonym: "G protein coupled receptor protein signaling pathway" EXACT [] +synonym: "G protein coupled receptor protein signalling pathway" EXACT [] +synonym: "G-protein coupled receptor protein signal transduction" EXACT [] +synonym: "G-protein coupled receptor protein signaling pathway" EXACT [GOC:bf] +synonym: "G-protein coupled receptor signaling pathway via GPCR dimer" NARROW [GOC:bf] +synonym: "G-protein coupled receptor signalling pathway" EXACT [] +synonym: "G-protein-coupled receptor protein signalling pathway" EXACT [] +synonym: "GPCR signaling pathway" EXACT [] +synonym: "GPCR signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0007187 +name: G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide." [GOC:mah, GOC:signaling, ISBN:0815316194] +synonym: "G protein signaling, coupled to cyclic nucleotide second messenger" EXACT [] +synonym: "G protein signalling, coupled to cyclic nucleotide second messenger" EXACT [] +synonym: "G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" EXACT [] +synonym: "G-protein signaling, coupled to cyclic nucleotide second messenger" EXACT [GOC:signaling] +synonym: "G-protein signalling, coupled to cyclic nucleotide second messenger" EXACT [] +synonym: "GPCR signaling pathway via cyclic nucleotide second messenger" EXACT [GOC:signaling] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: has_part GO:0019935 ! cyclic-nucleotide-mediated signaling + +[Term] +id: GO:0007188 +name: adenylate cyclase-modulating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP)." [GOC:mah, GOC:signaling, ISBN:0815316194] +comment: This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to 'regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway ; GO:0010578. +synonym: "adenylate cyclase-modulating GPCR signaling pathway" EXACT [GOC:signaling] +synonym: "G protein signaling, coupled to cAMP nucleotide second messenger" EXACT [] +synonym: "G protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT [] +synonym: "G protein signalling, coupled to cAMP nucleotide second messenger" EXACT [] +synonym: "G protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT [] +synonym: "G-protein signaling, coupled to cAMP nucleotide second messenger" EXACT [GOC:signaling] +synonym: "G-protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT [] +synonym: "G-protein signalling, coupled to cAMP nucleotide second messenger" EXACT [] +synonym: "G-protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT [] +synonym: "GPCR signaling pathway via cAMP second messenger" EXACT [GOC:signaling] +synonym: "GPCR signaling pathway via modulation of adenylate cyclase activity" EXACT [GOC:signaling] +is_a: GO:0007187 ! G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +relationship: has_part GO:0019933 ! cAMP-mediated signaling +relationship: has_part GO:0043949 ! regulation of cAMP-mediated signaling +relationship: has_part GO:0045761 ! regulation of adenylate cyclase activity + +[Term] +id: GO:0007189 +name: adenylate cyclase-activating G protein-coupled receptor signaling pathway +namespace: biological_process +alt_id: GO:0010579 +alt_id: GO:0010580 +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194] +comment: This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway. +synonym: "activation of adenylate cyclase activity by G-protein signaling pathway" RELATED [GOC:bf] +synonym: "activation of adenylate cyclase activity involved in G-protein signaling" RELATED [GOC:signaling] +synonym: "adenylate cyclase-activating GPCR signaling pathway" EXACT [GOC:signaling] +synonym: "G protein signaling, adenylate cyclase activating pathway" EXACT [] +synonym: "G protein signaling, adenylyl cyclase activating pathway" EXACT [] +synonym: "G protein signalling, adenylate cyclase activating pathway" EXACT [] +synonym: "G protein signalling, adenylyl cyclase activating pathway" EXACT [] +synonym: "G-protein signaling, adenylate cyclase activating pathway" EXACT [GOC:dph, GOC:tb] +synonym: "G-protein signaling, adenylyl cyclase activating pathway" EXACT [] +synonym: "G-protein signalling, adenylate cyclase activating pathway" EXACT [] +synonym: "G-protein signalling, adenylyl cyclase activating pathway" EXACT [] +synonym: "GPCR signaling pathway via activation of adenylate cyclase" EXACT [GOC:bf] +synonym: "GPCR signaling pathway via activation of adenylate cyclase activity" EXACT [GOC:signaling] +synonym: "positive regulation of adenylate cyclase activity by G-protein signaling pathway" RELATED [GOC:signaling] +synonym: "positive regulation of adenylate cyclase activity by G-protein signalling pathway" RELATED [GOC:mah] +synonym: "positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0007188 ! adenylate cyclase-modulating G protein-coupled receptor signaling pathway +is_a: GO:0019933 ! cAMP-mediated signaling +intersection_of: GO:0007188 ! adenylate cyclase-modulating G protein-coupled receptor signaling pathway +intersection_of: has_part GO:0007190 ! activation of adenylate cyclase activity +relationship: has_part GO:0007190 ! activation of adenylate cyclase activity + +[Term] +id: GO:0007190 +name: activation of adenylate cyclase activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme adenylate cyclase." [GOC:ai] +synonym: "adenylate cyclase activation" EXACT [GOC:dph, GOC:tb] +synonym: "adenylate cyclase activator" RELATED [] +synonym: "adenylyl cyclase activation" EXACT [] +is_a: GO:0050790 ! regulation of catalytic activity + +[Term] +id: GO:0007191 +name: adenylate cyclase-activating dopamine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:mah, GOC:signaling] +synonym: "activation of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of adenylate cyclase activity by dopamine receptor signalling pathway" RELATED [GOC:mah] +synonym: "dopamine receptor, adenylate cyclase activating pathway" EXACT [GOC:dph, GOC:tb] +synonym: "dopamine receptor, adenylyl cyclase activating pathway" EXACT [] +is_a: GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0007192 +name: adenylate cyclase-activating serotonin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "activation of adenylate cyclase activity by serotonin receptor signalling pathway" RELATED [GOC:mah] +synonym: "serotonin receptor, adenylate cyclase activating pathway" RELATED [GOC:dph, GOC:tb] +synonym: "serotonin receptor, adenylyl cyclase activating pathway" EXACT [] +is_a: GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:0007210 ! serotonin receptor signaling pathway + +[Term] +id: GO:0007193 +name: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194] +comment: This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase inhibition. +synonym: "adenylate cyclase-inhibiting GPCR signaling pathway" EXACT [GOC:signaling] +synonym: "G protein signaling, adenylate cyclase inhibiting pathway" EXACT [] +synonym: "G protein signaling, adenylyl cyclase inhibiting pathway" EXACT [] +synonym: "G protein signalling, adenylate cyclase inhibiting pathway" EXACT [] +synonym: "G protein signalling, adenylyl cyclase inhibiting pathway" EXACT [] +synonym: "G-protein signaling, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +synonym: "G-protein signaling, adenylyl cyclase inhibiting pathway" EXACT [] +synonym: "G-protein signalling, adenylate cyclase inhibiting pathway" EXACT [] +synonym: "G-protein signalling, adenylyl cyclase inhibiting pathway" EXACT [] +synonym: "GPCR signaling pathway via inhibition of adenylate cyclase activity" EXACT [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by G-protein signaling pathway" RELATED [GOC:signaling] +is_a: GO:0007188 ! adenylate cyclase-modulating G protein-coupled receptor signaling pathway +relationship: has_part GO:0007194 ! negative regulation of adenylate cyclase activity +relationship: has_part GO:0043951 ! negative regulation of cAMP-mediated signaling + +[Term] +id: GO:0007194 +name: negative regulation of adenylate cyclase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] +synonym: "adenylate cyclase inhibitor" RELATED [] +synonym: "down regulation of adenylate cyclase activity" EXACT [] +synonym: "down-regulation of adenylate cyclase activity" EXACT [] +synonym: "downregulation of adenylate cyclase activity" EXACT [] +synonym: "inhibition of adenylate cyclase activity" NARROW [] +synonym: "negative regulation of adenylyl cyclase activity" EXACT [] +is_a: GO:0031280 ! negative regulation of cyclase activity +is_a: GO:0045761 ! regulation of adenylate cyclase activity +is_a: GO:0051350 ! negative regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004016 ! adenylate cyclase activity +relationship: negatively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0007195 +name: adenylate cyclase-inhibiting dopamine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +synonym: "dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [] +synonym: "inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0007196 +name: adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway" EXACT [] +synonym: "inhibition of adenylate cyclase activity by G-protein-coupled glutamate receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway" EXACT [GOC:bf] +synonym: "inhibition of adenylate cyclase activity by metabotropic glutamate receptor signalling pathway" EXACT [GOC:mah] +synonym: "metabotropic glutamate receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +synonym: "metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway" EXACT [] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0007216 ! G protein-coupled glutamate receptor signaling pathway + +[Term] +id: GO:0007197 +name: adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway" RELATED [GOC:bf] +synonym: "inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway" RELATED [GOC:mah] +synonym: "muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +synonym: "muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway" EXACT [] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway + +[Term] +id: GO:0007198 +name: adenylate cyclase-inhibiting serotonin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "inhibition of adenylate cyclase activity by serotonin receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by serotonin receptor signalling pathway" RELATED [GOC:mah] +synonym: "serotonin receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +synonym: "serotonin receptor, adenylyl cyclase inhibiting pathway" RELATED [] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0098664 ! G protein-coupled serotonin receptor signaling pathway + +[Term] +id: GO:0007199 +name: G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP)." [GOC:mah, GOC:signaling, ISBN:0815316194] +synonym: "G protein signaling, coupled to cGMP nucleotide second messenger" EXACT [] +synonym: "G protein signalling, coupled to cGMP nucleotide second messenger" EXACT [] +synonym: "G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger" EXACT [] +synonym: "G-protein signaling, coupled to cGMP nucleotide second messenger" EXACT [GOC:signaling] +synonym: "G-protein signalling, coupled to cGMP nucleotide second messenger" EXACT [] +synonym: "GPCR signaling pathway via activation of guanylate cyclase activity" EXACT [GOC:signaling] +synonym: "GPCR signaling pathway via cGMP second messenger" EXACT [GOC:signaling] +synonym: "guanylate cyclase-activating G-protein coupled receptor signaling pathway" EXACT [GOC:signaling] +is_a: GO:0007187 ! G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +relationship: has_part GO:0019934 ! cGMP-mediated signaling +relationship: has_part GO:0031284 ! positive regulation of guanylate cyclase activity + +[Term] +id: GO:0007200 +name: phospholipase C-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194] +comment: This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity. +synonym: "activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:signaling] +synonym: "G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] +synonym: "G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] +synonym: "G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:signaling] +synonym: "G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:dph, GOC:tb] +synonym: "G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] +synonym: "phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:dph, GOC:tb] +synonym: "phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [] +synonym: "PLC-activating GPCR signaling pathway" EXACT [GOC:signaling] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: has_part GO:0007202 ! activation of phospholipase C activity +relationship: has_part GO:0048016 ! inositol phosphate-mediated signaling + +[Term] +id: GO:0007201 +name: obsolete G-protein dissociation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the dissociation of heterotrimeric G protein subunits is a consequence of a conformational change, which is in turn a consequence of ligand binding; it does not require multiple activities specifically to bring about. +synonym: "G-protein dissociation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007202 +name: activation of phospholipase C activity +namespace: biological_process +def: "The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand." [GOC:dph, GOC:mah, GOC:tb, PMID:8280098] +comment: Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'. +synonym: "phospholipase C activation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010863 ! positive regulation of phospholipase C activity + +[Term] +id: GO:0007203 +name: obsolete phosphatidylinositol-4,5-bisphosphate hydrolysis +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because hydrolysis is a reaction, not a process. +synonym: "phosphatidylinositol-4,5-bisphosphate hydrolysis" EXACT [] +is_obsolete: true +consider: GO:0004435 + +[Term] +id: GO:0007204 +name: positive regulation of cytosolic calcium ion concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the cytosol." [GOC:ai] +synonym: "cytoplasmic calcium ion concentration elevation" BROAD [] +synonym: "cytosolic calcium ion concentration elevation" EXACT [] +synonym: "elevation of calcium ion concentration in cytoplasm" BROAD [] +synonym: "elevation of calcium ion concentration in cytosol" EXACT [] +synonym: "elevation of cytoplasmic calcium ion concentration" BROAD [] +synonym: "elevation of cytosolic calcium ion concentration" EXACT [] +is_a: GO:0051480 ! regulation of cytosolic calcium ion concentration + +[Term] +id: GO:0007205 +name: protein kinase C-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG)." [GOC:mah, GOC:signaling] +synonym: "activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway" RELATED [GOC:signaling] +synonym: "activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway" RELATED [GOC:mah] +synonym: "protein kinase C-activating G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: has_part GO:1990051 ! activation of protein kinase C activity + +[Term] +id: GO:0007206 +name: phospholipase C-activating G protein-coupled glutamate receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway" RELATED [GOC:bf] +synonym: "activation of phospholipase C activity by metabotropic glutamate receptor signalling pathway" RELATED [GOC:mah] +synonym: "metabotropic glutamate receptor, phospholipase C activating pathway" RELATED [GOC:dph, GOC:tb] +synonym: "phospholipase C-activating G-protein coupled glutamate receptor signaling pathway" RELATED [] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0007216 ! G protein-coupled glutamate receptor signaling pathway + +[Term] +id: GO:0007207 +name: phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway" RELATED [GOC:bf] +synonym: "activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway" EXACT [GOC:mah] +synonym: "muscarinic acetylcholine receptor, phospholipase C activating pathway" RELATED [GOC:dph, GOC:tb] +synonym: "muscarinic receptor signaling pathway via activation of PLC" EXACT [GOC:signaling] +synonym: "phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway" EXACT [] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway + +[Term] +id: GO:0007208 +name: phospholipase C-activating serotonin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "activation of phospholipase C activity by serotonin receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of phospholipase C activity by serotonin receptor signalling pathway" RELATED [GOC:mah] +synonym: "serotonin receptor, phospholipase C activating pathway" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0098664 ! G protein-coupled serotonin receptor signaling pathway + +[Term] +id: GO:0007209 +name: phospholipase C-activating tachykinin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "activation of phospholipase C activity by tachykinin receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of phospholipase C activity by tachykinin receptor signalling pathway" RELATED [GOC:mah] +synonym: "tachykinin receptor, phospholipase C activating pathway" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0007217 ! tachykinin receptor signaling pathway + +[Term] +id: GO:0007210 +name: serotonin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "serotonin receptor signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:1903351 ! cellular response to dopamine + +[Term] +id: GO:0007211 +name: octopamine or tyramine signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters." [GOC:mah, PMID:15355245] +synonym: "octopamine or tyramine signalling pathway" EXACT [GOC:mah] +synonym: "octopamine/tyramine signaling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0007212 +name: dopamine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:mah, PMID:21711983] +synonym: "dopamine receptor signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: has_part GO:0001963 ! synaptic transmission, dopaminergic +relationship: part_of GO:1903351 ! cellular response to dopamine + +[Term] +id: GO:0007213 +name: G protein-coupled acetylcholine receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, ISBN:0815316194] +synonym: "acetylcholine receptor signalling, muscarinic pathway" EXACT [] +synonym: "G-protein coupled acetylcholine receptor signaling pathway" EXACT [] +synonym: "muscarinic acetylcholine receptor signaling pathway" EXACT [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0095500 ! acetylcholine receptor signaling pathway + +[Term] +id: GO:0007214 +name: gamma-aminobutyric acid signaling pathway +namespace: biological_process +def: "The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor." [GOC:mah] +synonym: "4-aminobutanoate signaling pathway" EXACT [] +synonym: "4-aminobutanoate signalling pathway" EXACT [] +synonym: "4-aminobutyrate signaling pathway" EXACT [] +synonym: "4-aminobutyrate signalling pathway" EXACT [] +synonym: "GABA signaling pathway" EXACT [] +synonym: "GABA signalling pathway" EXACT [] +synonym: "gamma-aminobutyric acid signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0007215 +name: glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:9131252] +synonym: "glutamate signaling pathway" EXACT [GOC:bf] +synonym: "glutamate signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0007216 +name: G protein-coupled glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:9131252] +synonym: "G-protein coupled glutamate receptor signaling pathway" EXACT [] +synonym: "metabotropic glutamate receptor signaling pathway" EXACT [GOC:bf] +synonym: "metabotropic glutamate receptor signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0007215 ! glutamate receptor signaling pathway + +[Term] +id: GO:0007217 +name: tachykinin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor." [GOC:mah, PMID:14723970] +synonym: "tachykinin signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0007218 +name: neuropeptide signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor." [GOC:mah, ISBN:0815316194] +synonym: "neuropeptide signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007219 +name: Notch signaling pathway +namespace: biological_process +alt_id: GO:0030179 +def: "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, GOC:signaling] +synonym: "N signaling pathway" EXACT [] +synonym: "N signalling pathway" EXACT [] +synonym: "Notch receptor signaling pathway" EXACT [] +synonym: "Notch receptor signalling pathway" EXACT [] +synonym: "Notch signalling pathway" EXACT [] +synonym: "Notch-receptor signaling pathway" EXACT [] +synonym: "Notch-receptor signalling pathway" EXACT [] +xref: Wikipedia:Notch_signaling_pathway +is_a: GO:0007166 ! cell surface receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007220 +name: Notch receptor processing +namespace: biological_process +def: "The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor." [PMID:12651094, PMID:14986688] +synonym: "N receptor processing" EXACT [] +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0007221 +name: positive regulation of transcription of Notch receptor target +namespace: biological_process +def: "The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain." [PMID:12651094] +synonym: "N receptor target transcription factor activation" RELATED [] +synonym: "Notch receptor target transcription factor activation" RELATED [] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +relationship: part_of GO:0007219 ! Notch signaling pathway + +[Term] +id: GO:0007223 +name: Wnt signaling pathway, calcium modulating pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:bf, GOC:dph, GOC:go_curators, PMID:11532397] +synonym: "frizzled-2 signaling pathway" NARROW [] +synonym: "frizzled-2 signalling pathway" NARROW [] +synonym: "non-canonical Wnt signaling pathway" RELATED [] +synonym: "Wnt receptor signaling pathway, calcium modulating pathway" EXACT [] +synonym: "Wnt-activated signaling pathway, calcium modulating pathway" EXACT [GOC:signaling] +is_a: GO:0035567 ! non-canonical Wnt signaling pathway + +[Term] +id: GO:0007224 +name: smoothened signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened." [GOC:mah, PMID:15205520] +synonym: "hedgehog signaling pathway" EXACT [] +synonym: "hh signaling pathway" NARROW [] +synonym: "hh signalling pathway" NARROW [] +synonym: "Shh signaling pathway" RELATED [GOC:dph] +synonym: "smoothened signalling pathway" EXACT [] +synonym: "Sonic hedgehog signaling pathway" NARROW [GOC:dph] +xref: Wikipedia:Hedgehog_signaling_pathway +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0007225 +name: patched ligand maturation +namespace: biological_process +def: "The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups." [PMID:15057936] +synonym: "Hedgehog protein processing" NARROW [] +synonym: "hh protein processing" EXACT [] +synonym: "patched ligand processing" RELATED [] +is_a: GO:0016486 ! peptide hormone processing + +[Term] +id: GO:0007227 +name: signal transduction downstream of smoothened +namespace: biological_process +def: "The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway." [PMID:15057936] +is_a: GO:0035556 ! intracellular signal transduction +relationship: part_of GO:0007224 ! smoothened signaling pathway + +[Term] +id: GO:0007228 +name: positive regulation of hh target transcription factor activity +namespace: biological_process +def: "Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited." [GOC:dph, GOC:tb, PMID:11912487, PMID:15057936] +synonym: "activation of hh target transcription factor" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of hedgehog target transcription factor" EXACT [GOC:bf, GOC:ecd] +is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity +relationship: part_of GO:0007227 ! signal transduction downstream of smoothened + +[Term] +id: GO:0007229 +name: integrin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] +synonym: "integrin-mediated signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0007230 +name: obsolete calcium-o-sensing receptor pathway +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it does not make sense. +synonym: "calcium-o-sensing receptor pathway" EXACT [] +is_obsolete: true +consider: GO:0019722 + +[Term] +id: GO:0007231 +name: osmosensory signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated in response to osmotic change." [GOC:jl] +synonym: "osmolarity sensing" EXACT [] +synonym: "osmolarity sensing signaling pathway" EXACT [] +synonym: "osmolarity sensing signalling pathway" EXACT [] +synonym: "osmosensory signal transduction" EXACT [GOC:signaling] +synonym: "osmosensory signalling pathway" EXACT [] +synonym: "signal transduction during osmotic stress" EXACT [] +is_a: GO:0007165 ! signal transduction +is_a: GO:0071470 ! cellular response to osmotic stress + +[Term] +id: GO:0007232 +name: osmosensory signaling pathway via Sho1 osmosensor +namespace: biological_process +def: "A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system." [GOC:jl] +synonym: "osmosensory signalling pathway via Sho1 osmosensor" EXACT [] +synonym: "signal transduction during osmotic stress via Sho1 osmosensor" EXACT [] +is_a: GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0007234 +name: osmosensory signaling via phosphorelay pathway +namespace: biological_process +def: "A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system." [PMID:9843501] +synonym: "osmolarity sensing via two-component system" EXACT [] +synonym: "osmolarity signaling pathway via two-component system" EXACT [] +synonym: "osmolarity signalling pathway via two-component system" EXACT [] +synonym: "osmosensory signaling pathway via two-component system" NARROW [] +synonym: "osmosensory signalling pathway via two-component system" EXACT [] +synonym: "signal transduction during osmotic stress via two-component system" EXACT [] +is_a: GO:0000160 ! phosphorelay signal transduction system +is_a: GO:0007231 ! osmosensory signaling pathway + +[Term] +id: GO:0007235 +name: obsolete activation of Ypd1 protein +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "activation of Ypd1 protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007236 +name: obsolete activation of Ssk1 protein +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "activation of Ssk1 protein" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007237 +name: obsolete activation of Ssk2/Ssk22 proteins +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "activation of Ssk2/Ssk22 proteins" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007238 +name: obsolete activation of Pbs2 +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "activation of Pbs2" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007239 +name: obsolete activation of Hog1 +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "activation of Hog1" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007240 +name: obsolete nuclear translocation of Hog1 +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "nuclear translocation of Hog1" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007241 +name: obsolete inactivation of Hog1 +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains gene product and species specific information. +synonym: "inactivation of Hog1" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007244 +name: obsolete MAPKKK cascade (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "MAPKKK cascade (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0007245 +name: obsolete activation of MAPKKK (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKKK (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0007246 +name: obsolete activation of MAPKK (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKK (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0007247 +name: obsolete activation of MAPK (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPK (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +consider: GO:0000750 + +[Term] +id: GO:0007248 +name: obsolete nuclear translocation of MAPK (mating sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "nuclear translocation of MAPK (mating sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0007249 +name: I-kappaB kinase/NF-kappaB signaling +namespace: biological_process +def: "The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:12773372, Reactome:R-HSA-209560] +synonym: "activation of the inhibitor of kappa kinase" RELATED [] +synonym: "canonical NF-kappaB signaling cascade" EXACT [GOC:bf] +synonym: "I-kappaB kinase/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "I-kappaB kinase/NF-kappaB signal transduction" EXACT [GOC:signaling] +synonym: "NF-kappaB cascade" BROAD [] +synonym: "p50-dependent NF-kappaB signaling" RELATED [PMID:18292232] +is_a: GO:0035556 ! intracellular signal transduction +relationship: has_part GO:0051092 ! positive regulation of NF-kappaB transcription factor activity + +[Term] +id: GO:0007250 +name: activation of NF-kappaB-inducing kinase activity +namespace: biological_process +def: "The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues." [GOC:jl, PMID:12773372] +synonym: "activation of NIK activity" EXACT [GOC:bf] +synonym: "positive regulation of NF-kappaB-inducing kinase activity" BROAD [] +is_a: GO:0032147 ! activation of protein kinase activity +is_a: GO:1901224 ! positive regulation of NIK/NF-kappaB signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004704 ! NF-kappaB-inducing kinase activity +relationship: part_of GO:0038061 ! NIK/NF-kappaB signaling +relationship: positively_regulates GO:0004704 ! NF-kappaB-inducing kinase activity + +[Term] +id: GO:0007251 +name: obsolete activation of the inhibitor of kappa kinase +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because its meaning was unclear. +synonym: "activation of the inhibitor of kappa kinase" EXACT [] +is_obsolete: true +consider: GO:0007249 + +[Term] +id: GO:0007252 +name: I-kappaB phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:21772278, PMID:7594468] +synonym: "IkappaB phosphorylation" EXACT [GOC:bf] +synonym: "IKB phosphorylation" EXACT [GOC:bf] +synonym: "inhibitor of kappaB phosphorylation" EXACT [GOC:bf] +synonym: "inhibitor of NF-kappaB phosphorylation" EXACT [GOC:bf] +is_a: GO:0006468 ! protein phosphorylation +relationship: part_of GO:0007249 ! I-kappaB kinase/NF-kappaB signaling +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0007253 +name: cytoplasmic sequestering of NF-kappaB +namespace: biological_process +def: "The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus." [GOC:jl] +synonym: "cytoplasmic NF-kappaB retention" EXACT [] +synonym: "cytoplasmic NF-kappaB sequestration" EXACT [] +synonym: "cytoplasmic NF-kappaB storage" EXACT [] +synonym: "cytoplasmic retention of NF-kappaB" EXACT [] +synonym: "cytoplasmic sequestration of NF-kappaB" EXACT [] +synonym: "cytoplasmic storage of NF-kappaB" EXACT [] +synonym: "maintenance of NF-kappaB location in cytoplasm" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032088 ! negative regulation of NF-kappaB transcription factor activity +is_a: GO:0042994 ! cytoplasmic sequestering of transcription factor + +[Term] +id: GO:0007254 +name: JNK cascade +namespace: biological_process +def: "An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:signaling, PMID:11790549, PMID:20811974] +synonym: "c-Jun N-terminal kinase cascade" EXACT [PMID:20811974] +synonym: "JNK1 cascade" NARROW [GOC:add] +synonym: "JNK2 cascade" NARROW [GOC:add] +synonym: "JNK3 cascade" NARROW [GOC:add] +synonym: "MAPK10 cascade" NARROW [GOC:add] +synonym: "MAPK8 cascade" NARROW [GOC:add] +synonym: "MAPK9 cascade" NARROW [GOC:add] +synonym: "SAPK cascade" BROAD [] +synonym: "stress-activated protein kinase cascade" BROAD [] +is_a: GO:0051403 ! stress-activated MAPK cascade + +[Term] +id: GO:0007256 +name: activation of JNKK activity +namespace: biological_process +def: "The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress." [GOC:bf, PMID:11790549] +synonym: "activation of JUN kinase kinase activity" EXACT [] +synonym: "positive regulation of JUNKK activity" BROAD [] +is_a: GO:0000186 ! activation of MAPKK activity +is_a: GO:0043507 ! positive regulation of JUN kinase activity +relationship: part_of GO:0007254 ! JNK cascade +relationship: positively_regulates GO:0008545 ! JUN kinase kinase activity + +[Term] +id: GO:0007257 +name: activation of JUN kinase activity +namespace: biological_process +def: "The initiation of the activity of the inactive enzyme JUN kinase (JNK)." [GOC:bf] +synonym: "activation of SAPK activity" BROAD [] +is_a: GO:0000187 ! activation of MAPK activity +is_a: GO:0043507 ! positive regulation of JUN kinase activity +relationship: part_of GO:0007254 ! JNK cascade +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0007258 +name: JUN phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into a JUN protein." [GOC:jl] +is_a: GO:0006468 ! protein phosphorylation +relationship: part_of GO:0007254 ! JNK cascade +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0007259 +name: receptor signaling pathway via JAK-STAT +namespace: biological_process +def: "Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins." [GOC:bf, GOC:jl, GOC:signaling, PMID:12039028] +synonym: "JAK-STAT cascade" NARROW [] +synonym: "JAK-STAT signal transduction" EXACT [GOC:signaling] +xref: Wikipedia:JAK-STAT_signaling_pathway +is_a: GO:0097696 ! receptor signaling pathway via STAT + +[Term] +id: GO:0007260 +name: tyrosine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:0042502 +alt_id: GO:0042503 +alt_id: GO:0042504 +alt_id: GO:0042505 +alt_id: GO:0042506 +alt_id: GO:0042507 +alt_id: GO:0042508 +def: "The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] +synonym: "tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "tyrosine phosphorylation of Stat7 protein" NARROW [] +is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation +relationship: part_of GO:0007259 ! receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0007261 +name: obsolete JAK-induced STAT protein dimerization +namespace: biological_process +def: "OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases." [GOC:jl, PMID:12039028] +comment: This term was made obsolete because it is ambiguous, and protein dimerization is represented by molecular function terms. +synonym: "JAK-induced STAT protein dimerization" EXACT [] +is_obsolete: true +consider: GO:0007260 +consider: GO:0046983 + +[Term] +id: GO:0007263 +name: nitric oxide mediated signal transduction +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms." [GOC:jl, PMID:21549190] +synonym: "nitric oxide signaling" EXACT [GOC:bf] +synonym: "nitric oxide-mediated signal transduction" EXACT [] +synonym: "NO mediated signal transduction" EXACT [] +synonym: "NO-mediated signal transduction" EXACT [] +is_a: GO:0019932 ! second-messenger-mediated signaling + +[Term] +id: GO:0007264 +name: small GTPase mediated signal transduction +namespace: biological_process +def: "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals." [GOC:mah] +synonym: "small GTPase-mediated signal transduction" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0007265 +name: Ras protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state." [GOC:bf] +synonym: "Ras mediated signal transduction" EXACT [] +is_a: GO:0007264 ! small GTPase mediated signal transduction + +[Term] +id: GO:0007266 +name: Rho protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state." [GOC:bf] +synonym: "Rho mediated signal transduction" EXACT [] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0007267 +name: cell-cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +synonym: "cell-cell signalling" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0023052 ! signaling + +[Term] +id: GO:0007268 +name: chemical synaptic transmission +namespace: biological_process +def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435] +subset: goslim_synapse +synonym: "neurotransmission" RELATED [GOC:dph] +synonym: "signal transmission across a synapse" BROAD [] +synonym: "synaptic transmission" BROAD [] +xref: Wikipedia:Neurotransmission +is_a: GO:0098916 ! anterograde trans-synaptic signaling + +[Term] +id: GO:0007269 +name: neurotransmitter secretion +namespace: biological_process +alt_id: GO:0010554 +def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph] +comment: A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. +subset: goslim_synapse +synonym: "neurotransmitter release" EXACT [] +synonym: "neurotransmitter secretory pathway" EXACT [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099643 ! signal release from synapse +relationship: occurs_in GO:0098793 ! presynapse +relationship: part_of GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0007270 +name: neuron-neuron synaptic transmission +namespace: biological_process +def: "The process of synaptic transmission from a neuron to another neuron across a synapse." [GOC:add, GOC:dos, GOC:jl, MeSH:D009435] +synonym: "nerve-nerve synaptic transmission" RELATED [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0007271 +name: synaptic transmission, cholinergic +namespace: biological_process +def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] +synonym: "cholinergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0007272 +name: ensheathment of neurons +namespace: biological_process +def: "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment." [GOC:dgh, GOC:dph, GOC:tb] +synonym: "ionic insulation of neurons by glial cells" RELATED [] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0007273 +name: obsolete regulation of synapse +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the term string made no sense. +synonym: "regulation of synapse" EXACT [] +is_obsolete: true +consider: GO:0007268 + +[Term] +id: GO:0007274 +name: neuromuscular synaptic transmission +namespace: biological_process +def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0007275 +name: multicellular organism development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] +comment: Note that this term was 'developmental process'. +subset: goslim_chembl +subset: goslim_plant +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0007276 +name: gamete generation +namespace: biological_process +alt_id: GO:0009552 +def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] +synonym: "gametogenesis" RELATED [] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0019953 ! sexual reproduction +property_value: RO:0002161 NCBITaxon_Union:0000023 + +[Term] +id: GO:0007277 +name: pole cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048468 ! cell development +relationship: part_of GO:0007276 ! gamete generation + +[Term] +id: GO:0007278 +name: pole cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +is_a: GO:0001709 ! cell fate determination +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007277 ! pole cell development + +[Term] +id: GO:0007279 +name: pole cell formation +namespace: biological_process +def: "Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells." [GOC:bf, PMID:9988212] +comment: See also the Cell Ontology term 'pole cell ; CL:0000301'. +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0007349 ! cellularization +relationship: part_of GO:0007277 ! pole cell development + +[Term] +id: GO:0007280 +name: pole cell migration +namespace: biological_process +def: "The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form." [GOC:bf, PMID:9988212] +comment: See also the Cell Ontology term 'pole cell ; CL:0000301'. +is_a: GO:0008354 ! germ cell migration + +[Term] +id: GO:0007281 +name: germ cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] +synonym: "germ-cell development" EXACT [] +synonym: "primordial germ cell development" NARROW [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048468 ! cell development +relationship: part_of GO:0007276 ! gamete generation + +[Term] +id: GO:0007282 +name: cystoblast division +namespace: biological_process +def: "Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells." [PMID:21452446] +synonym: "cystoblast cell division" EXACT [] +is_a: GO:0008356 ! asymmetric cell division +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007281 ! germ cell development + +[Term] +id: GO:0007283 +name: spermatogenesis +namespace: biological_process +def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821] +synonym: "generation of spermatozoa" EXACT systematic_synonym [] +xref: Wikipedia:Spermatogenesis +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048232 ! male gamete generation + +[Term] +id: GO:0007284 +name: spermatogonial cell division +namespace: biological_process +def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238] +comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. +synonym: "spermatogonium division" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051301 ! cell division +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0007285 +name: primary spermatocyte growth +namespace: biological_process +def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0007286 +name: spermatid development +namespace: biological_process +def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators] +synonym: "spermatid cell development" EXACT [] +synonym: "spermiogenesis" EXACT [] +xref: Wikipedia:Spermiogenesis +is_a: GO:0007281 ! germ cell development +relationship: part_of GO:0048515 ! spermatid differentiation + +[Term] +id: GO:0007287 +name: Nebenkern assembly +namespace: biological_process +def: "Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern." [GOC:bf, ISBN:0879694238] +comment: See also the cellular component term 'Nebenkern ; GO:0016006', and the fly_anatomy.ontology term 'Nebenkern ; FBbt:00004943'. +synonym: "Nebenkern assembly" EXACT [PMID:9550716] +synonym: "Nebenkern formation" RELATED [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0007286 ! spermatid development + +[Term] +id: GO:0007288 +name: sperm axoneme assembly +namespace: biological_process +def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0035082 ! axoneme assembly +relationship: part_of GO:0007286 ! spermatid development +relationship: part_of GO:0030317 ! flagellated sperm motility + +[Term] +id: GO:0007289 +name: spermatid nucleus differentiation +namespace: biological_process +def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah] +comment: See also the Cell Ontology term 'spermatid ; CL:0000018'. +synonym: "spermatid nuclear differentiation" EXACT [] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007286 ! spermatid development + +[Term] +id: GO:0007290 +name: spermatid nucleus elongation +namespace: biological_process +def: "The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation." [GOC:bf, GOC:dph, GOC:jl, GOC:mah, ISBN:0879694238] +synonym: "spermatid nuclear elongation" EXACT [] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007289 ! spermatid nucleus differentiation + +[Term] +id: GO:0007291 +name: sperm individualization +namespace: biological_process +def: "The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane." [GOC:bf, PMID:9550716] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0007349 ! cellularization +relationship: part_of GO:0007286 ! spermatid development + +[Term] +id: GO:0007292 +name: female gamete generation +namespace: biological_process +def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732] +is_a: GO:0007276 ! gamete generation + +[Term] +id: GO:0007293 +name: germarium-derived egg chamber formation +namespace: biological_process +def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0007294 +name: germarium-derived oocyte fate determination +namespace: biological_process +alt_id: GO:0016350 +def: "The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "maintenance of oocyte identity" RELATED [] +synonym: "oocyte cell fate determination" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030716 ! oocyte fate determination +relationship: part_of GO:0030706 ! germarium-derived oocyte differentiation + +[Term] +id: GO:0007295 +name: growth of a germarium-derived egg chamber +namespace: biological_process +def: "Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "egg chamber growth" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0007296 +name: vitellogenesis +namespace: biological_process +def: "The production of yolk. Yolk is a mixture of materials used for embryonic nutrition." [GOC:dph, ISBN:0879694238] +synonym: "yolk formation" EXACT [] +synonym: "yolk production" EXACT systematic_synonym [] +xref: Wikipedia:Vitellogenesis +is_a: GO:0007028 ! cytoplasm organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007292 ! female gamete generation + +[Term] +id: GO:0007297 +name: ovarian follicle cell migration +namespace: biological_process +def: "The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] +synonym: "follicle cell migration" BROAD [] +is_a: GO:0010631 ! epithelial cell migration +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0007298 +name: border follicle cell migration +namespace: biological_process +def: "The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] +synonym: "border cell migration" BROAD [] +is_a: GO:0007297 ! ovarian follicle cell migration + +[Term] +id: GO:0007299 +name: ovarian follicle cell-cell adhesion +namespace: biological_process +def: "The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12642496] +synonym: "follicle cell adhesion" BROAD [] +synonym: "ovarian follicle cell adhesion" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0090136 ! epithelial cell-cell adhesion +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0007300 +name: ovarian nurse cell to oocyte transport +namespace: biological_process +def: "Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "nurse cell to oocyte transport" BROAD [] +is_a: GO:0006810 ! transport +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0007301 +name: female germline ring canal formation +namespace: biological_process +def: "Assembly of the intercellular bridges that connect the germ-line cells of a female cyst." [ISBN:0879694238] +synonym: "nurse cell ring canal formation" NARROW [] +synonym: "ovarian ring canal formation" NARROW [] +is_a: GO:0030725 ! germline ring canal formation +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation +relationship: part_of GO:0007300 ! ovarian nurse cell to oocyte transport + +[Term] +id: GO:0007302 +name: nurse cell nucleus anchoring +namespace: biological_process +def: "Attachment of the nurse cell nucleus to the plasma membrane." [ISBN:0879694238] +is_a: GO:0051647 ! nucleus localization + +[Term] +id: GO:0007303 +name: cytoplasmic transport, nurse cell to oocyte +namespace: biological_process +def: "The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte." [ISBN:0879694238] +is_a: GO:0016482 ! cytosolic transport +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007300 ! ovarian nurse cell to oocyte transport + +[Term] +id: GO:0007304 +name: chorion-containing eggshell formation +namespace: biological_process +def: "The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +synonym: "eggshell formation" BROAD [] +is_a: GO:0030703 ! eggshell formation +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0007305 +name: vitelline membrane formation involved in chorion-containing eggshell formation +namespace: biological_process +def: "Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +synonym: "vitelline membrane formation in chorion-containing eggshell" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030704 ! vitelline membrane formation +intersection_of: GO:0030704 ! vitelline membrane formation +intersection_of: part_of GO:0007304 ! chorion-containing eggshell formation +relationship: part_of GO:0007304 ! chorion-containing eggshell formation + +[Term] +id: GO:0007306 +name: eggshell chorion assembly +namespace: biological_process +def: "Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] +synonym: "eggshell chorion formation" EXACT [GOC:dph, GOC:tb] +synonym: "insect chorion formation" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045229 ! external encapsulating structure organization +relationship: part_of GO:0007304 ! chorion-containing eggshell formation + +[Term] +id: GO:0007307 +name: eggshell chorion gene amplification +namespace: biological_process +def: "Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster." [GOC:mtg_sensu, PMID:11157771] +is_a: GO:0006277 ! DNA amplification +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007306 ! eggshell chorion assembly + +[Term] +id: GO:0007308 +name: oocyte construction +namespace: biological_process +alt_id: GO:0048110 +def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732] +synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0048599 ! oocyte development + +[Term] +id: GO:0007309 +name: oocyte axis specification +namespace: biological_process +alt_id: GO:0048111 +def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "oocyte axis determination" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0007308 ! oocyte construction + +[Term] +id: GO:0007310 +name: oocyte dorsal/ventral axis specification +namespace: biological_process +alt_id: GO:0008072 +alt_id: GO:0048123 +def: "The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "oocyte dorsal-ventral axis specification" EXACT [GOC:mah] +synonym: "oocyte dorsal/ventral axis determination" RELATED [GOC:dph, GOC:tb] +synonym: "oocyte dorsoventral axis specification" EXACT [GOC:mah] +is_a: GO:0007309 ! oocyte axis specification +is_a: GO:0009950 ! dorsal/ventral axis specification + +[Term] +id: GO:0007311 +name: maternal specification of dorsal/ventral axis, oocyte, germ-line encoded +namespace: biological_process +alt_id: GO:0048124 +def: "Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] +synonym: "maternal determination of dorsal/ventral axis, oocyte, germ-line encoded" EXACT [GOC:dph, GOC:tb] +synonym: "maternal specification of dorsal-ventral axis, oocyte, germ-line encoded" EXACT [GOC:mah] +synonym: "maternal specification of dorsoventral axis, oocyte, germ-line encoded" EXACT [GOC:mah] +is_a: GO:0007310 ! oocyte dorsal/ventral axis specification + +[Term] +id: GO:0007312 +name: oocyte nucleus migration involved in oocyte dorsal/ventral axis specification +namespace: biological_process +alt_id: GO:0008102 +alt_id: GO:0030722 +alt_id: GO:0048126 +alt_id: GO:0048128 +def: "The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mah, GOC:mtg_sensu, GOC:tb] +synonym: "establishment of localization of oocyte nucleus during oocyte axis determination" BROAD [] +synonym: "establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification" RELATED [GOC:mah] +synonym: "establishment of oocyte nucleus localization during oocyte axis determination" BROAD [GOC:dph, GOC:tb] +synonym: "establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification" RELATED [GOC:mah] +synonym: "establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination" RELATED [GOC:dph, GOC:tb] +synonym: "establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification" RELATED [] +synonym: "establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification" RELATED [GOC:mah] +synonym: "nucleus positioning in oocyte during oocyte axis determination" BROAD [] +synonym: "oocyte axis determination, establishment of localization of nucleus" BROAD [] +synonym: "oocyte axis determination, establishment of oocyte nucleus localization" BROAD [] +synonym: "oocyte axis determination, establishment of position of nucleus" BROAD [] +synonym: "oocyte axis determination, oocyte nuclear migration" EXACT [] +synonym: "oocyte axis determination, oocyte nucleus migration" EXACT [] +synonym: "oocyte axis determination, positioning of nucleus" BROAD [] +synonym: "oocyte nuclear migration during oocyte axis determination" EXACT [] +synonym: "oocyte nucleus migration during oocyte axis determination" EXACT [GOC:dph, GOC:tb] +synonym: "oocyte nucleus migration during oocyte axis specification" RELATED [GOC:dph, GOC:tb] +synonym: "oocyte nucleus positioning during oocyte axis determination" BROAD [] +is_a: GO:0007097 ! nuclear migration +is_a: GO:0051663 ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification +intersection_of: GO:0007097 ! nuclear migration +intersection_of: part_of GO:0007310 ! oocyte dorsal/ventral axis specification + +[Term] +id: GO:0007313 +name: maternal specification of dorsal/ventral axis, oocyte, soma encoded +namespace: biological_process +alt_id: GO:0048125 +def: "Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] +synonym: "maternal determination of dorsal/ventral axis, oocyte, soma encoded" EXACT [GOC:dph, GOC:tb] +synonym: "maternal specification of dorsal-ventral axis, oocyte, soma encoded" EXACT [GOC:mah] +synonym: "maternal specification of dorsoventral axis, oocyte, soma encoded" EXACT [GOC:mah] +is_a: GO:0007310 ! oocyte dorsal/ventral axis specification + +[Term] +id: GO:0007314 +name: oocyte anterior/posterior axis specification +namespace: biological_process +alt_id: GO:0048112 +def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] +synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007309 ! oocyte axis specification +is_a: GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0008358 ! maternal determination of anterior/posterior axis, embryo + +[Term] +id: GO:0007315 +name: pole plasm assembly +namespace: biological_process +alt_id: GO:0048113 +def: "Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu] +is_a: GO:0007028 ! cytoplasm organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0007314 ! oocyte anterior/posterior axis specification + +[Term] +id: GO:0007316 +name: pole plasm RNA localization +namespace: biological_process +alt_id: GO:0048116 +def: "Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [GOC:ai] +synonym: "establishment and maintenance of pole plasm RNA localization" EXACT [] +synonym: "oocyte pole plasm RNA localization" EXACT [] +synonym: "pole plasm RNA localisation" EXACT [GOC:mah] +is_a: GO:0006403 ! RNA localization +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007315 ! pole plasm assembly + +[Term] +id: GO:0007317 +name: regulation of pole plasm oskar mRNA localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm." [GOC:hb] +synonym: "regulation of oocyte pole plasm oskar mRNA localization" EXACT [] +synonym: "regulation of pole plasm oskar mRNA localisation" EXACT [GOC:mah] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0060281 ! regulation of oocyte development +is_a: GO:1902875 ! regulation of embryonic pattern specification +is_a: GO:1903429 ! regulation of cell maturation +is_a: GO:1904580 ! regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045451 ! pole plasm oskar mRNA localization +relationship: regulates GO:0045451 ! pole plasm oskar mRNA localization + +[Term] +id: GO:0007318 +name: pole plasm protein localization +namespace: biological_process +alt_id: GO:0048115 +def: "Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [GOC:ai] +synonym: "establishment and maintenance of pole plasm protein localization" EXACT [] +synonym: "oocyte pole plasm protein localization" EXACT [] +synonym: "pole plasm protein localisation" EXACT [GOC:mah] +is_a: GO:0008104 ! protein localization +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007315 ! pole plasm assembly + +[Term] +id: GO:0007319 +name: negative regulation of oskar mRNA translation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein." [GOC:ems] +synonym: "down regulation of oskar mRNA translation" EXACT [] +synonym: "down-regulation of oskar mRNA translation" EXACT [] +synonym: "downregulation of oskar mRNA translation" EXACT [] +synonym: "inhibition of oskar mRNA translation" NARROW [] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0046011 ! regulation of oskar mRNA translation + +[Term] +id: GO:0007320 +name: insemination +namespace: biological_process +def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089] +xref: Wikipedia:Insemination +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007620 ! copulation + +[Term] +id: GO:0007321 +name: sperm displacement +namespace: biological_process +def: "The physical displacement of sperm stored from previous mating encounters." [PMID:10440373] +is_a: GO:0046692 ! sperm competition + +[Term] +id: GO:0007323 +name: peptide pheromone maturation +namespace: biological_process +alt_id: GO:0007324 +alt_id: GO:0007326 +alt_id: GO:0046613 +def: "The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae." [GOC:elh] +synonym: "pheromone processing" EXACT [] +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0007329 +name: positive regulation of transcription from RNA polymerase II promoter by pheromones +namespace: biological_process +def: "Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:go_curators] +synonym: "activation of transcription from RNA polymerase II promoter by pheromones" NARROW [] +synonym: "positive regulation of transcription from Pol II promoter by pheromones" EXACT [] +synonym: "stimulation of transcription from RNA polymerase II promoter by pheromones" NARROW [] +synonym: "up regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +synonym: "up-regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +synonym: "upregulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +is_a: GO:0009371 ! positive regulation of transcription by pheromones +is_a: GO:0046019 ! regulation of transcription from RNA polymerase II promoter by pheromones +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus + +[Term] +id: GO:0007336 +name: obsolete bilateral process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it gives no indication of what it refers to. +synonym: "bilateral process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007337 +name: obsolete unilateral process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it gives no indication of what it refers to. +synonym: "unilateral process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007338 +name: single fertilization +namespace: biological_process +def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu] +synonym: "zygote biosynthesis" RELATED [] +synonym: "zygote formation" RELATED [] +is_a: GO:0009566 ! fertilization +property_value: RO:0002161 NCBITaxon:58024 + +[Term] +id: GO:0007339 +name: binding of sperm to zona pellucida +namespace: biological_process +def: "The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place." [GOC:dph, ISBN:0878932437] +synonym: "ZPG binding" RELATED [] +is_a: GO:0035036 ! sperm-egg recognition + +[Term] +id: GO:0007340 +name: acrosome reaction +namespace: biological_process +def: "The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida." [GOC:dph, PMID:11175768, PMID:21042299, PMID:3886029] +comment: If the release of the acrosome content occurs before the sperm reaches the zona pellucida, consider using premature acrosome loss. +xref: Wikipedia:Acrosome_reaction +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0007341 +name: penetration of zona pellucida +namespace: biological_process +def: "The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm." [GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html] +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0007342 +name: fusion of sperm to egg plasma membrane involved in single fertilization +namespace: biological_process +def: "The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head." [GOC:dph, GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html] +synonym: "sperm-oocyte fusion" NARROW [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045026 ! plasma membrane fusion +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0007343 +name: egg activation +namespace: biological_process +def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751] +xref: Wikipedia:Egg_activation +is_a: GO:0001775 ! cell activation +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0007344 +name: pronuclear fusion +namespace: biological_process +def: "The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome." [GOC:ems, ISBN:087969307X] +is_a: GO:0000741 ! karyogamy +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0007345 +name: obsolete embryogenesis and morphogenesis +namespace: biological_process +def: "OBSOLETE. Formation and development of an embryo and its organized structures." [GOC:ems, ISBN:0070524300, ISBN:0140512888] +comment: This term was made obsolete because more appropriate terms were created. Morphogenesis in plants also occurs outside of embryogenesis. +synonym: "embryogenesis and morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0009653 +consider: GO:0009790 + +[Term] +id: GO:0007346 +name: regulation of mitotic cell cycle +namespace: biological_process +def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "mitotic cell cycle modulation" EXACT [] +synonym: "mitotic cell cycle regulation" EXACT [] +synonym: "mitotic cell cycle regulator" RELATED [] +synonym: "modulation of mitotic cell cycle progression" EXACT [] +synonym: "regulation of mitotic cell cycle progression" EXACT [] +synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000278 ! mitotic cell cycle +relationship: regulates GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0007347 +name: regulation of preblastoderm mitotic cell cycle +namespace: biological_process +def: "A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "modulation of preblastoderm mitotic cell cycle progression" EXACT [] +synonym: "preblastoderm mitotic cell cycle modulation" EXACT [] +synonym: "preblastoderm mitotic cell cycle regulation" EXACT [] +synonym: "preblastoderm mitotic cell cycle regulator" RELATED [] +synonym: "regulation of preblastoderm mitotic cell cycle progression" EXACT [] +synonym: "regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009794 ! regulation of mitotic cell cycle, embryonic +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035185 ! preblastoderm mitotic cell cycle +relationship: regulates GO:0035185 ! preblastoderm mitotic cell cycle + +[Term] +id: GO:0007348 +name: regulation of syncytial blastoderm mitotic cell cycle +namespace: biological_process +def: "A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "modulation of syncytial blastoderm cell cycle progression" EXACT [] +synonym: "regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of syncytial blastoderm cell cycle" EXACT [] +synonym: "regulation of syncytial blastoderm cell cycle progression" EXACT [] +synonym: "syncytial blastoderm cell cycle modulation" EXACT [] +synonym: "syncytial blastoderm cell cycle regulation" EXACT [] +synonym: "syncytial blastoderm cell cycle regulator" RELATED [] +is_a: GO:0009794 ! regulation of mitotic cell cycle, embryonic +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle +relationship: regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle + +[Term] +id: GO:0007349 +name: cellularization +namespace: biological_process +alt_id: GO:0009796 +def: "The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development." [GOC:go_curators, GOC:mtg_sensu, ISBN:0716731363] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007350 +name: blastoderm segmentation +namespace: biological_process +def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0009880 ! embryonic pattern specification +is_a: GO:0035282 ! segmentation + +[Term] +id: GO:0007351 +name: tripartite regional subdivision +namespace: biological_process +def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007350 ! blastoderm segmentation + +[Term] +id: GO:0007352 +name: zygotic specification of dorsal/ventral axis +namespace: biological_process +def: "The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote." [GOC:bf] +synonym: "zygotic determination of dorsal-ventral axis" RELATED [GOC:mah] +synonym: "zygotic determination of dorsal/ventral axis" RELATED [GOC:dph] +synonym: "zygotic determination of dorsoventral axis" RELATED [GOC:mah] +is_a: GO:0000578 ! embryonic axis specification +is_a: GO:0009950 ! dorsal/ventral axis specification + +[Term] +id: GO:0007353 +name: obsolete ventral/lateral system +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "ventral/lateral system" EXACT [] +is_obsolete: true +consider: GO:0009880 + +[Term] +id: GO:0007354 +name: zygotic determination of anterior/posterior axis, embryo +namespace: biological_process +def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0008595 ! anterior/posterior axis specification, embryo + +[Term] +id: GO:0007355 +name: anterior region determination +namespace: biological_process +def: "Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0007354 ! zygotic determination of anterior/posterior axis, embryo + +[Term] +id: GO:0007356 +name: thorax and anterior abdomen determination +namespace: biological_process +def: "Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0007354 ! zygotic determination of anterior/posterior axis, embryo + +[Term] +id: GO:0007357 +name: obsolete positive regulation of central gap gene transcription +namespace: biological_process +def: "OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products." [ISBN:0879694238] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of central gap gene" BROAD [] +synonym: "activation of central gap gene transcription" NARROW [] +synonym: "stimulation of central gap gene transcription" NARROW [] +synonym: "up regulation of central gap gene transcription" EXACT [] +synonym: "up-regulation of central gap gene transcription" EXACT [] +synonym: "upregulation of central gap gene transcription" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007358 +name: establishment of central gap gene boundaries +namespace: biological_process +def: "Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0007356 ! thorax and anterior abdomen determination + +[Term] +id: GO:0007359 +name: posterior abdomen determination +namespace: biological_process +def: "The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +comment: Note that this process is exemplified in insects by the actions of the knirps gene product. +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0007354 ! zygotic determination of anterior/posterior axis, embryo + +[Term] +id: GO:0007360 +name: obsolete positive regulation of posterior gap gene transcription +namespace: biological_process +def: "OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene." [ISBN:0879694238] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of posterior gap gene" BROAD [] +synonym: "activation of posterior gap gene transcription" NARROW [] +synonym: "knirps activation" NARROW [] +synonym: "stimulation of posterior gap gene transcription" NARROW [] +synonym: "up regulation of posterior gap gene transcription" EXACT [] +synonym: "up-regulation of posterior gap gene transcription" EXACT [] +synonym: "upregulation of posterior gap gene transcription" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007361 +name: establishment of posterior gap gene boundaries +namespace: biological_process +def: "Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0007359 ! posterior abdomen determination + +[Term] +id: GO:0007362 +name: terminal region determination +namespace: biological_process +def: "Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0009880 ! embryonic pattern specification +relationship: part_of GO:0007354 ! zygotic determination of anterior/posterior axis, embryo + +[Term] +id: GO:0007363 +name: obsolete positive regulation of terminal gap gene transcription +namespace: biological_process +def: "OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes." [ISBN:0879694238] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of terminal gap gene" BROAD [] +synonym: "activation of terminal gap gene transcription" NARROW [] +synonym: "stimulation of terminal gap gene transcription" NARROW [] +synonym: "up regulation of terminal gap gene transcription" EXACT [] +synonym: "up-regulation of terminal gap gene transcription" EXACT [] +synonym: "upregulation of terminal gap gene transcription" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007364 +name: establishment of terminal gap gene boundary +namespace: biological_process +def: "Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0007362 ! terminal region determination + +[Term] +id: GO:0007365 +name: periodic partitioning +namespace: biological_process +def: "The regionalization process that divides the spatial regions of an embryo into serially repeated regions." [GOC:dph, GOC:isa_complete, GOC:ma] +comment: Note that examples of periodic partitions are tagmata, segments or parasegments. +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007350 ! blastoderm segmentation + +[Term] +id: GO:0007366 +name: periodic partitioning by pair rule gene +namespace: biological_process +def: "Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0632030488, ISBN:0879694238] +is_a: GO:0007365 ! periodic partitioning +is_a: GO:0009952 ! anterior/posterior pattern specification + +[Term] +id: GO:0007367 +name: segment polarity determination +namespace: biological_process +def: "Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0632030488, ISBN:0879694238] +is_a: GO:0007365 ! periodic partitioning + +[Term] +id: GO:0007368 +name: determination of left/right symmetry +namespace: biological_process +def: "The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry." [GOC:dph, GOC:jid] +synonym: "determination of left/right asymmetry" EXACT [GOC:dph] +is_a: GO:0009855 ! determination of bilateral symmetry + +[Term] +id: GO:0007369 +name: gastrulation +namespace: biological_process +def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] +subset: goslim_drosophila +xref: Wikipedia:Gastrulation +is_a: GO:0048598 ! embryonic morphogenesis +relationship: has_part GO:0001705 ! ectoderm formation +relationship: has_part GO:0001706 ! endoderm formation +relationship: has_part GO:0001707 ! mesoderm formation + +[Term] +id: GO:0007370 +name: ventral furrow formation +namespace: biological_process +def: "Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation." [ISBN:0879694238] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007371 +name: ventral midline determination +namespace: biological_process +alt_id: GO:0007372 +alt_id: GO:0007373 +def: "The regionalization process in which the area where the ventral midline will form is specified." [GOC:bf, GOC:isa_complete, GOC:vk] +synonym: "determination of anterior border of ventral midline" NARROW [] +synonym: "determination of posterior border of ventral midline" NARROW [] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007418 ! ventral midline development + +[Term] +id: GO:0007374 +name: posterior midgut invagination +namespace: biological_process +def: "Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior." [ISBN:0879694238] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007375 +name: anterior midgut invagination +namespace: biological_process +def: "Internalization of the anterior midgut into the interior of the embryo." [ISBN:0879694238] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007376 +name: cephalic furrow formation +namespace: biological_process +def: "Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome." [ISBN:0879694238] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007377 +name: germ-band extension +namespace: biological_process +def: "Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further." [ISBN:0879694238] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007378 +name: amnioserosa formation +namespace: biological_process +def: "Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift." [ISBN:0879694238] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0010004 ! gastrulation involving germ band extension + +[Term] +id: GO:0007379 +name: segment specification +namespace: biological_process +def: "The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0035282 ! segmentation + +[Term] +id: GO:0007380 +name: specification of segmental identity, head +namespace: biological_process +def: "The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +is_a: GO:0007379 ! segment specification +relationship: part_of GO:0035287 ! head segmentation + +[Term] +id: GO:0007381 +name: specification of segmental identity, labial segment +namespace: biological_process +def: "The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +comment: See also the fly_anatomy.ontology term 'labial segment ; FBbt:00000014'. +is_a: GO:0007380 ! specification of segmental identity, head +relationship: part_of GO:0035289 ! posterior head segmentation + +[Term] +id: GO:0007382 +name: specification of segmental identity, maxillary segment +namespace: biological_process +def: "The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +comment: See also the fly_anatomy.ontology term 'maxillary segment ; FBbt:00000013'. +is_a: GO:0007380 ! specification of segmental identity, head +relationship: part_of GO:0035289 ! posterior head segmentation + +[Term] +id: GO:0007383 +name: specification of segmental identity, antennal segment +namespace: biological_process +def: "The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +comment: See also the fly_anatomy.ontology term 'antennal segment ; FBbt:00000009'. +is_a: GO:0007380 ! specification of segmental identity, head +relationship: part_of GO:0035288 ! anterior head segmentation + +[Term] +id: GO:0007384 +name: specification of segmental identity, thorax +namespace: biological_process +def: "The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +is_a: GO:0035292 ! specification of segmental identity, trunk + +[Term] +id: GO:0007385 +name: specification of segmental identity, abdomen +namespace: biological_process +def: "The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +is_a: GO:0035292 ! specification of segmental identity, trunk + +[Term] +id: GO:0007386 +name: compartment pattern specification +namespace: biological_process +def: "The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +synonym: "compartment specification" RELATED [GOC:dph] +is_a: GO:0009952 ! anterior/posterior pattern specification + +[Term] +id: GO:0007387 +name: anterior compartment pattern formation +namespace: biological_process +def: "The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +synonym: "anterior compartment pattern specification" RELATED [GOC:dph] +is_a: GO:0007386 ! compartment pattern specification + +[Term] +id: GO:0007388 +name: posterior compartment specification +namespace: biological_process +def: "The process involved in the specification of cell identity in the posterior compartments of the segmented embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0007386 ! compartment pattern specification + +[Term] +id: GO:0007389 +name: pattern specification process +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125] +subset: goslim_drosophila +synonym: "pattern biosynthesis" RELATED [] +synonym: "pattern formation" RELATED [] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007390 +name: germ-band shortening +namespace: biological_process +def: "The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo." [GOC:bf, PMID:12147138] +synonym: "germ-band retraction" EXACT [] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0007391 +name: dorsal closure +namespace: biological_process +def: "The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally." [PMID:9224720] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0007392 +name: initiation of dorsal closure +namespace: biological_process +def: "Events that occur at the start of dorsal closure." [GOC:bf] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007391 ! dorsal closure + +[Term] +id: GO:0007393 +name: dorsal closure, leading edge cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:bf, GOC:go_curators, PMID:12147138] +is_a: GO:0035028 ! leading edge cell fate determination +intersection_of: GO:0035028 ! leading edge cell fate determination +intersection_of: part_of GO:0007391 ! dorsal closure +relationship: part_of GO:0035029 ! dorsal closure, leading edge cell fate commitment + +[Term] +id: GO:0007394 +name: dorsal closure, elongation of leading edge cells +namespace: biological_process +def: "The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis." [PMID:12147138] +is_a: GO:0009826 ! unidimensional cell growth +is_a: GO:0016476 ! regulation of embryonic cell shape +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007392 ! initiation of dorsal closure + +[Term] +id: GO:0007395 +name: dorsal closure, spreading of leading edge cells +namespace: biological_process +def: "Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa." [GOC:bf, PMID:12147138] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0007391 ! dorsal closure + +[Term] +id: GO:0007396 +name: suture of dorsal opening +namespace: biological_process +def: "Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole." [GOC:bf, PMID:12147138] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007391 ! dorsal closure + +[Term] +id: GO:0007397 +name: obsolete histogenesis and organogenesis +namespace: biological_process +def: "OBSOLETE. The generation of organized tissues or of whole organs." [GOC:ems] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "histogenesis and organogenesis" EXACT [] +is_obsolete: true +consider: GO:0009887 +consider: GO:0009888 + +[Term] +id: GO:0007398 +name: ectoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0007399 +name: nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] +subset: goslim_drosophila +synonym: "pan-neural process" RELATED [] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0007400 +name: neuroblast fate determination +namespace: biological_process +alt_id: GO:0007408 +alt_id: GO:0043347 +alt_id: GO:0043348 +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus." [GOC:go_curators] +synonym: "neuroblast cell fate determination" EXACT [] +synonym: "neuroblast identity determination" EXACT [] +is_a: GO:0048867 ! stem cell fate determination +relationship: part_of GO:0014017 ! neuroblast fate commitment + +[Term] +id: GO:0007401 +name: obsolete pan-neural process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because its meaning is ambiguous. +synonym: "pan-neural process" EXACT [] +is_obsolete: true +consider: GO:0007399 +consider: GO:0050877 + +[Term] +id: GO:0007402 +name: ganglion mother cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +is_a: GO:0048867 ! stem cell fate determination + +[Term] +id: GO:0007403 +name: glial cell fate determination +namespace: biological_process +alt_id: GO:0043361 +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0021781 ! glial cell fate commitment + +[Term] +id: GO:0007405 +name: neuroblast proliferation +namespace: biological_process +alt_id: GO:0043349 +alt_id: GO:0043350 +def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] +is_a: GO:0061351 ! neural precursor cell proliferation +is_a: GO:0072089 ! stem cell proliferation +relationship: part_of GO:0048699 ! generation of neurons + +[Term] +id: GO:0007406 +name: negative regulation of neuroblast proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] +synonym: "down regulation of neuroblast proliferation" EXACT [] +synonym: "down-regulation of neuroblast proliferation" EXACT [] +synonym: "downregulation of neuroblast proliferation" EXACT [] +synonym: "inhibition of neuroblast proliferation" NARROW [] +synonym: "suppression of neuroblast proliferation" EXACT [] +is_a: GO:0050768 ! negative regulation of neurogenesis +is_a: GO:1902692 ! regulation of neuroblast proliferation +is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation +is_a: GO:2000647 ! negative regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007405 ! neuroblast proliferation +relationship: negatively_regulates GO:0007405 ! neuroblast proliferation + +[Term] +id: GO:0007407 +name: neuroblast activation +namespace: biological_process +alt_id: GO:0043351 +alt_id: GO:0043352 +def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0001775 ! cell activation +relationship: part_of GO:0048699 ! generation of neurons + +[Term] +id: GO:0007409 +name: axonogenesis +namespace: biological_process +alt_id: GO:0007410 +def: "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." [GOC:dph, GOC:jid, GOC:pg, GOC:pr, ISBN:0198506732] +comment: Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon). +synonym: "axon growth" NARROW [] +synonym: "axon morphogenesis" EXACT [GOC:bf, PMID:23517308] +synonym: "neuron long process generation" EXACT systematic_synonym [] +is_a: GO:0048812 ! neuron projection morphogenesis +relationship: part_of GO:0048667 ! cell morphogenesis involved in neuron differentiation +relationship: part_of GO:0061564 ! axon development + +[Term] +id: GO:0007411 +name: axon guidance +namespace: biological_process +alt_id: GO:0008040 +def: "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." [ISBN:0878932437] +synonym: "axon chemotaxis" RELATED [] +synonym: "axon growth cone guidance" NARROW [] +synonym: "axon pathfinding" EXACT [GOC:mah] +xref: Wikipedia:Axon_guidance +is_a: GO:0097485 ! neuron projection guidance +relationship: part_of GO:0007409 ! axonogenesis + +[Term] +id: GO:0007412 +name: axon target recognition +namespace: biological_process +def: "The process in which an axon recognizes and binds to a set of cells with which it may form stable connections." [ISBN:0878932437] +is_a: GO:0007154 ! cell communication +relationship: part_of GO:0007409 ! axonogenesis + +[Term] +id: GO:0007413 +name: axonal fasciculation +namespace: biological_process +def: "The collection of axons into a bundle of rods, known as a fascicle." [GOC:dgh] +synonym: "fasciculation of neuron" RELATED [] +is_a: GO:0008038 ! neuron recognition +is_a: GO:0106030 ! neuron projection fasciculation +relationship: part_of GO:0061564 ! axon development + +[Term] +id: GO:0007414 +name: axonal defasciculation +namespace: biological_process +def: "Separation of axons away from a bundle of axons known as a fascicle." [GOC:dgh, ISBN:039751820X] +synonym: "defasciculation of neuron" RELATED [] +is_a: GO:0008038 ! neuron recognition +relationship: part_of GO:0061564 ! axon development + +[Term] +id: GO:0007415 +name: defasciculation of motor neuron axon +namespace: biological_process +def: "Separation of a motor axon away from a bundle of axons known as a fascicle." [GOC:dgh] +is_a: GO:0007414 ! axonal defasciculation + +[Term] +id: GO:0007416 +name: synapse assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah] +subset: goslim_synapse +synonym: "synapse biogenesis" EXACT [GOC:mah] +synonym: "synaptogenesis" EXACT [GOC:mah] +xref: Wikipedia:Synaptogenesis +is_a: GO:0034329 ! cell junction assembly +is_a: GO:0050808 ! synapse organization +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0007417 +name: central nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] +synonym: "CNS development" EXACT [] +xref: Wikipedia:Neural_development +is_a: GO:0048731 ! system development +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0007418 +name: ventral midline development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate." [GOC:bf, GOC:go_curators, PMID:12075342] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0007419 +name: ventral cord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms." [GOC:bf, GOC:go_curators, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0007420 +name: brain development +namespace: biological_process +def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0007417 ! central nervous system development +relationship: part_of GO:0060322 ! head development + +[Term] +id: GO:0007421 +name: stomatogastric nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0048731 ! system development +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0007422 +name: peripheral nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] +is_a: GO:0048731 ! system development +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0007423 +name: sensory organ development +namespace: biological_process +def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] +synonym: "sense organ development" EXACT [GOC:dph] +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0007424 +name: open tracheal system development +namespace: biological_process +def: "The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:8625828] +comment: See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'. +is_a: GO:0060541 ! respiratory system development + +[Term] +id: GO:0007425 +name: epithelial cell fate determination, open tracheal system +namespace: biological_process +alt_id: GO:0046846 +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11063940] +synonym: "tracheal cell fate determination" BROAD [] +synonym: "tracheal epithelial cell fate determination" EXACT [] +synonym: "tracheal placode cell fate determination" RELATED [] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0007426 +name: tracheal outgrowth, open tracheal system +namespace: biological_process +def: "The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0007427 +name: epithelial cell migration, open tracheal system +namespace: biological_process +def: "The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "tracheal cell migration" BROAD [] +synonym: "tracheal epithelial cell migration" RELATED [] +is_a: GO:0010631 ! epithelial cell migration +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0007428 +name: primary branching, open tracheal system +namespace: biological_process +def: "Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:29844090] +synonym: "primary tracheal branching" EXACT [] +is_a: GO:0060446 ! branching involved in open tracheal system development + +[Term] +id: GO:0007429 +name: secondary branching, open tracheal system +namespace: biological_process +def: "Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:29844090] +synonym: "secondary tracheal branching" EXACT [] +is_a: GO:0060446 ! branching involved in open tracheal system development + +[Term] +id: GO:0007430 +name: terminal branching, open tracheal system +namespace: biological_process +def: "Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:29844090] +synonym: "terminal branching of trachea, cytoplasmic projection extension" EXACT [] +is_a: GO:0060446 ! branching involved in open tracheal system development + +[Term] +id: GO:0007431 +name: salivary gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity." [GOC:jid, UBERON:0001044] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035272 ! exocrine system development + +[Term] +id: GO:0007432 +name: salivary gland boundary specification +namespace: biological_process +def: "Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [PMID:11598957] +synonym: "salivary gland determination" EXACT [] +is_a: GO:0010160 ! formation of animal organ boundary +relationship: part_of GO:0007431 ! salivary gland development + +[Term] +id: GO:0007433 +name: larval salivary gland boundary specification +namespace: biological_process +def: "Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [GOC:tb, PMID:11598957] +synonym: "larval salivary gland determination" BROAD [GOC:tb] +is_a: GO:0007432 ! salivary gland boundary specification +relationship: part_of GO:0002168 ! instar larval development + +[Term] +id: GO:0007434 +name: adult salivary gland boundary specification +namespace: biological_process +def: "Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland." [GOC:tb, PMID:11598957] +synonym: "larval salivary gland determination" BROAD [GOC:tb] +is_a: GO:0007432 ! salivary gland boundary specification + +[Term] +id: GO:0007435 +name: salivary gland morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the salivary gland are generated and organized." [GOC:jid] +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0007431 ! salivary gland development + +[Term] +id: GO:0007436 +name: larval salivary gland morphogenesis +namespace: biological_process +def: "The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized." [GOC:jid] +is_a: GO:0007435 ! salivary gland morphogenesis +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0002168 ! instar larval development + +[Term] +id: GO:0007437 +name: adult salivary gland morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the adult salivary gland are generated and organized." [GOC:go_curators] +is_a: GO:0007435 ! salivary gland morphogenesis + +[Term] +id: GO:0007438 +name: oenocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments." [GOC:bf, PMID:11171397] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0001742 ! oenocyte differentiation + +[Term] +id: GO:0007439 +name: ectodermal digestive tract development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators] +synonym: "ectodermal gut development" RELATED [GOC:dph] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0048565 ! digestive tract development + +[Term] +id: GO:0007440 +name: foregut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048546 ! digestive tract morphogenesis + +[Term] +id: GO:0007441 +name: anterior midgut (ectodermal) morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized." [GOC:go_curators] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0048567 ! ectodermal digestive tract morphogenesis + +[Term] +id: GO:0007442 +name: hindgut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048546 ! digestive tract morphogenesis +relationship: part_of GO:0061525 ! hindgut development + +[Term] +id: GO:0007443 +name: Malpighian tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut." [GOC:bf, ISBN:0582227089] +comment: See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'. +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0061333 ! renal tubule morphogenesis +relationship: part_of GO:0048619 ! embryonic hindgut morphogenesis +relationship: part_of GO:0072002 ! Malpighian tubule development + +[Term] +id: GO:0007444 +name: imaginal disc development +namespace: biological_process +def: "The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)." [GOC:bf, ISBN:0879694238] +is_a: GO:0035295 ! tube development +is_a: GO:0048513 ! animal organ development +is_a: GO:0060429 ! epithelium development + +[Term] +id: GO:0007445 +name: determination of imaginal disc primordium +namespace: biological_process +def: "Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment." [ISBN:0879694238] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0007444 ! imaginal disc development + +[Term] +id: GO:0007446 +name: imaginal disc growth +namespace: biological_process +def: "The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:bf, GOC:jid, PMID:10679387] +is_a: GO:0035265 ! organ growth +relationship: part_of GO:0007444 ! imaginal disc development + +[Term] +id: GO:0007447 +name: imaginal disc pattern formation +namespace: biological_process +def: "The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:dph, GOC:isa_complete, GOC:jid] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007444 ! imaginal disc development + +[Term] +id: GO:0007448 +name: anterior/posterior pattern specification, imaginal disc +namespace: biological_process +def: "The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form." [GOC:bf, ISBN:0879694238] +is_a: GO:0007447 ! imaginal disc pattern formation +is_a: GO:0009952 ! anterior/posterior pattern specification + +[Term] +id: GO:0007449 +name: proximal/distal pattern formation, imaginal disc +namespace: biological_process +def: "The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed." [GOC:jid, ISBN:0879694238] +is_a: GO:0007447 ! imaginal disc pattern formation +is_a: GO:0009954 ! proximal/distal pattern formation + +[Term] +id: GO:0007450 +name: dorsal/ventral pattern formation, imaginal disc +namespace: biological_process +def: "The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed." [GOC:jid, ISBN:0879694238] +synonym: "dorsal-ventral pattern formation, imaginal disc" EXACT [GOC:mah] +synonym: "dorsoventral pattern formation, imaginal disc" EXACT [GOC:mah] +is_a: GO:0007447 ! imaginal disc pattern formation +is_a: GO:0009953 ! dorsal/ventral pattern formation + +[Term] +id: GO:0007451 +name: dorsal/ventral lineage restriction, imaginal disc +namespace: biological_process +def: "Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf, PMID:10625531, PMID:9374402] +synonym: "dorsal-ventral lineage restriction, imaginal disc" EXACT [GOC:mah] +synonym: "dorsoventral lineage restriction, imaginal disc" EXACT [GOC:mah] +is_a: GO:0035161 ! imaginal disc lineage restriction +relationship: part_of GO:0007450 ! dorsal/ventral pattern formation, imaginal disc + +[Term] +id: GO:0007453 +name: clypeo-labral disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus." [GOC:bf, ISBN:0879694238] +synonym: "clypeo-labral disc metamorphosis" EXACT [] +synonym: "morphogenesis of structures derived from the clypeo-labral disc" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0007454 +name: labial disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis." [GOC:bf, ISBN:0879694238] +synonym: "labial disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035217 ! labial disc development + +[Term] +id: GO:0007455 +name: eye-antennal disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238] +synonym: "eye-antennal disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035214 ! eye-antennal disc development + +[Term] +id: GO:0007458 +name: progression of morphogenetic furrow involved in compound eye morphogenesis +namespace: biological_process +def: "The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc." [PMID:3076112, PMID:3937883] +synonym: "progression of morphogenetic furrow during compound eye morphogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0007460 +name: R8 cell fate commitment +namespace: biological_process +alt_id: GO:0007461 +def: "The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium." [PMID:3076112, PMID:3937883] +synonym: "restriction of R8 fate" EXACT [] +is_a: GO:0001752 ! compound eye photoreceptor fate commitment +relationship: part_of GO:0045465 ! R8 cell differentiation + +[Term] +id: GO:0007462 +name: R1/R6 cell fate commitment +namespace: biological_process +def: "The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883] +is_a: GO:0001752 ! compound eye photoreceptor fate commitment +relationship: part_of GO:0048052 ! R1/R6 cell differentiation + +[Term] +id: GO:0007463 +name: R2/R5 cell fate commitment +namespace: biological_process +def: "The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883] +is_a: GO:0001752 ! compound eye photoreceptor fate commitment +relationship: part_of GO:0048054 ! R2/R5 cell differentiation + +[Term] +id: GO:0007464 +name: R3/R4 cell fate commitment +namespace: biological_process +def: "The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres." [PMID:3076112, PMID:3937883] +is_a: GO:0001752 ! compound eye photoreceptor fate commitment +relationship: part_of GO:0042067 ! establishment of ommatidial planar polarity +relationship: part_of GO:0048056 ! R3/R4 cell differentiation + +[Term] +id: GO:0007465 +name: R7 cell fate commitment +namespace: biological_process +def: "The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium." [PMID:3076112, PMID:3937883] +is_a: GO:0001752 ! compound eye photoreceptor fate commitment +relationship: part_of GO:0045466 ! R7 cell differentiation + +[Term] +id: GO:0007468 +name: regulation of rhodopsin gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression +relationship: part_of GO:0042461 ! photoreceptor cell development + +[Term] +id: GO:0007469 +name: antennal development +namespace: biological_process +def: "The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli." [http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526] +is_a: GO:0035114 ! imaginal disc-derived appendage morphogenesis +relationship: part_of GO:0035214 ! eye-antennal disc development + +[Term] +id: GO:0007470 +name: prothoracic disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle." [GOC:bf, ISBN:0879694238] +synonym: "prothoracic disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035219 ! prothoracic disc development + +[Term] +id: GO:0007471 +name: obsolete prothoracic morphogenesis +namespace: biological_process +def: "OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized." [GOC:jid] +comment: This term was made obsolete because it does not stipulate which anatomical part is involved in the process. +synonym: "prothoracic morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0007470 + +[Term] +id: GO:0007472 +name: wing disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura." [GOC:bf, ISBN:0879694238] +synonym: "wing disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035220 ! wing disc development + +[Term] +id: GO:0007473 +name: wing disc proximal/distal pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing." [GOC:bf] +is_a: GO:0007449 ! proximal/distal pattern formation, imaginal disc +is_a: GO:0035222 ! wing disc pattern formation + +[Term] +id: GO:0007474 +name: imaginal disc-derived wing vein specification +namespace: biological_process +def: "The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified." [GOC:dph, GOC:isa_complete, GOC:mtg_sensu] +synonym: "wing vein specification" EXACT [] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis + +[Term] +id: GO:0007475 +name: apposition of dorsal and ventral imaginal disc-derived wing surfaces +namespace: biological_process +def: "The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing." [GOC:bf, GOC:mtg_sensu] +synonym: "apposition of dorsal and ventral wing surfaces" EXACT [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0008587 ! imaginal disc-derived wing margin morphogenesis + +[Term] +id: GO:0007476 +name: imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu] +synonym: "wing morphogenesis" EXACT [] +is_a: GO:0035114 ! imaginal disc-derived appendage morphogenesis +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +relationship: part_of GO:0007472 ! wing disc morphogenesis + +[Term] +id: GO:0007477 +name: notum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035220 ! wing disc development + +[Term] +id: GO:0007478 +name: leg disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura." [GOC:bf, ISBN:0879694238] +synonym: "leg disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035218 ! leg disc development + +[Term] +id: GO:0007479 +name: leg disc proximal/distal pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg." [GOC:bf] +is_a: GO:0007449 ! proximal/distal pattern formation, imaginal disc +is_a: GO:0035223 ! leg disc pattern formation + +[Term] +id: GO:0007480 +name: imaginal disc-derived leg morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +is_a: GO:0035114 ! imaginal disc-derived appendage morphogenesis +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +relationship: part_of GO:0007478 ! leg disc morphogenesis + +[Term] +id: GO:0007481 +name: haltere disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum." [GOC:bf, ISBN:0879694238] +synonym: "haltere disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035216 ! haltere disc development + +[Term] +id: GO:0007482 +name: haltere development +namespace: biological_process +def: "The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings." [GOC:jid, http://www.earthlife.net] +is_a: GO:0048737 ! imaginal disc-derived appendage development +relationship: part_of GO:0035216 ! haltere disc development + +[Term] +id: GO:0007483 +name: genital disc morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut." [GOC:bf, ISBN:0879694238] +synonym: "genital disc metamorphosis" EXACT [] +is_a: GO:0007560 ! imaginal disc morphogenesis +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0007484 +name: imaginal disc-derived genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu] +synonym: "genital development" BROAD [] +is_a: GO:0048806 ! genitalia development +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0007485 +name: imaginal disc-derived male genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu] +synonym: "male genital development" BROAD [] +is_a: GO:0007484 ! imaginal disc-derived genitalia development + +[Term] +id: GO:0007486 +name: imaginal disc-derived female genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster." [GOC:ai, GOC:sensu] +synonym: "female genital development" BROAD [] +is_a: GO:0007484 ! imaginal disc-derived genitalia development +is_a: GO:0030540 ! female genitalia development + +[Term] +id: GO:0007487 +name: analia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster." [GOC:ai, GOC:mtg_sensu] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0007488 +name: histoblast morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen." [GOC:bf, ISBN:0879694238] +synonym: "histoblast metamorphosis" EXACT [] +is_a: GO:0000902 ! cell morphogenesis +is_a: GO:0007560 ! imaginal disc morphogenesis + +[Term] +id: GO:0007489 +name: maintenance of imaginal histoblast diploidy +namespace: biological_process +def: "The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells." [GOC:bf, ISBN:0879694238] +is_a: GO:0045596 ! negative regulation of cell differentiation +relationship: part_of GO:0007488 ! histoblast morphogenesis + +[Term] +id: GO:0007490 +name: tergite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment." [GOC:jid, http://www.earthlife.net] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007488 ! histoblast morphogenesis + +[Term] +id: GO:0007491 +name: sternite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment." [GOC:jid, http://www.earthlife.net] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007488 ! histoblast morphogenesis + +[Term] +id: GO:0007492 +name: endoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb] +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0007493 +name: endodermal cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, ISBN:0878932437] +comment: Note that this term was 'endoderm determination'. Changed string to make it more consistent with parent term 'cell fate determination'. +synonym: "endoderm cell fate determination" EXACT [] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0001711 ! endodermal cell fate commitment + +[Term] +id: GO:0007494 +name: midgut development +namespace: biological_process +def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045] +is_a: GO:0048565 ! digestive tract development + +[Term] +id: GO:0007495 +name: visceral mesoderm-endoderm interaction involved in midgut development +namespace: biological_process +def: "The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut." [GOC:dph, GOC:isa_complete] +synonym: "visceral mesoderm/endoderm interaction" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0007494 ! midgut development + +[Term] +id: GO:0007496 +name: anterior midgut development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007494 ! midgut development + +[Term] +id: GO:0007497 +name: posterior midgut development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007494 ! midgut development + +[Term] +id: GO:0007498 +name: mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0007499 +name: ectoderm and mesoderm interaction +namespace: biological_process +def: "A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm." [GOC:isa_complete] +synonym: "ectoderm/mesoderm interaction" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0007498 ! mesoderm development + +[Term] +id: GO:0007500 +name: mesodermal cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators, ISBN:0878932437] +comment: Note that this term was 'mesoderm determination'. Changed string to make more consistent with parent term 'cell fate determination'. +synonym: "mesoderm cell fate determination" EXACT [] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0001710 ! mesodermal cell fate commitment + +[Term] +id: GO:0007501 +name: mesodermal cell fate specification +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] +comment: Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'. +synonym: "mesoderm cell fate specification" EXACT [] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0001710 ! mesodermal cell fate commitment + +[Term] +id: GO:0007502 +name: digestive tract mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism." [GOC:ai] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0007498 ! mesoderm development +relationship: part_of GO:0048565 ! digestive tract development + +[Term] +id: GO:0007503 +name: fat body development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism." [ISBN:0582227089] +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0007504 +name: larval fat body development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life." [GOC:bf, ISBN:0879694238] +is_a: GO:0007503 ! fat body development +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0002168 ! instar larval development + +[Term] +id: GO:0007505 +name: adult fat body development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body." [GOC:bf, ISBN:0879694238] +is_a: GO:0007503 ! fat body development + +[Term] +id: GO:0007506 +name: gonadal mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai] +is_a: GO:0007498 ! mesoderm development +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0008406 ! gonad development + +[Term] +id: GO:0007507 +name: heart development +namespace: biological_process +alt_id: GO:0007511 +def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] +synonym: "cardiac development" RELATED [] +synonym: "dorsal vessel development" NARROW [] +xref: Wikipedia:Heart_development +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0072359 ! circulatory system development + +[Term] +id: GO:0007508 +name: larval heart development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper." [GOC:bf, ISBN:0879694238] +is_a: GO:0007507 ! heart development +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0002164 ! larval development + +[Term] +id: GO:0007509 +name: mesoderm migration involved in gastrulation +namespace: biological_process +def: "The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism." [GOC:isa_complete, GOC:sat] +is_a: GO:0008078 ! mesodermal cell migration +is_a: GO:0042074 ! cell migration involved in gastrulation +is_a: GO:0090130 ! tissue migration +relationship: part_of GO:0001707 ! mesoderm formation + +[Term] +id: GO:0007510 +name: cardioblast cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +is_a: GO:0060913 ! cardiac cell fate determination +relationship: part_of GO:0042684 ! cardioblast cell fate commitment + +[Term] +id: GO:0007512 +name: adult heart development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure." [GOC:bf] +synonym: "adult cardiac development" RELATED [] +is_a: GO:0007507 ! heart development + +[Term] +id: GO:0007515 +name: obsolete lymph gland development +namespace: biological_process +def: "OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system." [GOC:jid] +comment: This term was made obsolete because it was wrongly defined. +synonym: "lymph gland development" EXACT [] +is_obsolete: true +consider: GO:0048535 +consider: GO:0048542 + +[Term] +id: GO:0007516 +name: hemocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] +synonym: "arthropod blood cell development" EXACT [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0007517 +name: muscle organ development +namespace: biological_process +def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732] +is_a: GO:0048513 ! animal organ development +is_a: GO:0061061 ! muscle structure development + +[Term] +id: GO:0007518 +name: myoblast fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0048625 ! myoblast fate commitment + +[Term] +id: GO:0007519 +name: skeletal muscle tissue development +namespace: biological_process +alt_id: GO:0048637 +def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle] +synonym: "myogenesis" RELATED [] +is_a: GO:0014706 ! striated muscle tissue development +relationship: part_of GO:0060538 ! skeletal muscle organ development + +[Term] +id: GO:0007520 +name: myoblast fusion +namespace: biological_process +def: "A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle] +is_a: GO:0000768 ! syncytium formation by plasma membrane fusion +relationship: part_of GO:0014902 ! myotube differentiation + +[Term] +id: GO:0007521 +name: muscle cell fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed." [CL:0000187, GOC:go_curators] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0042693 ! muscle cell fate commitment + +[Term] +id: GO:0007522 +name: visceral muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0007517 ! muscle organ development + +[Term] +id: GO:0007523 +name: larval visceral muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0007522 ! visceral muscle development +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0002164 ! larval development + +[Term] +id: GO:0007524 +name: adult visceral muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0007522 ! visceral muscle development + +[Term] +id: GO:0007525 +name: somatic muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle." [GOC:jid, GOC:mtg_muscle] +is_a: GO:0061061 ! muscle structure development + +[Term] +id: GO:0007526 +name: larval somatic muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0007525 ! somatic muscle development +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0002164 ! larval development + +[Term] +id: GO:0007527 +name: adult somatic muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0007525 ! somatic muscle development + +[Term] +id: GO:0007528 +name: neuromuscular junction development +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013] +synonym: "neuromuscular junction organization" EXACT [] +synonym: "neuromuscular junction stability" RELATED [GOC:pr] +synonym: "NMJ stability" RELATED [GOC:pr] +is_a: GO:0050808 ! synapse organization + +[Term] +id: GO:0007529 +name: establishment of synaptic specificity at neuromuscular junction +namespace: biological_process +def: "The biological process in which a synapse between a motor neuron and a muscle is initially formed." [GOC:isa_complete] +is_a: GO:0050808 ! synapse organization +relationship: part_of GO:0007528 ! neuromuscular junction development + +[Term] +id: GO:0007530 +name: sex determination +namespace: biological_process +def: "Any process that establishes and transmits the specification of sexual status of an individual organism." [ISBN:0198506732] +xref: Wikipedia:Sex-determination_system +is_a: GO:0003006 ! developmental process involved in reproduction + +[Term] +id: GO:0007531 +name: mating type determination +namespace: biological_process +def: "Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms." [http://www.biology-text.com/] +is_a: GO:0007530 ! sex determination +is_a: GO:0045165 ! cell fate commitment + +[Term] +id: GO:0007532 +name: regulation of mating-type specific transcription, DNA-templated +namespace: biological_process +def: "Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "mating-type specific transcriptional control" EXACT [] +synonym: "regulation of mating-type specific transcription, DNA-dependent" EXACT [GOC:txnOH] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0007531 ! mating type determination + +[Term] +id: GO:0007533 +name: mating type switching +namespace: biological_process +def: "The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [PMID:9928492] +synonym: "mating type switching and recombination" RELATED [] +is_a: GO:0007531 ! mating type determination +is_a: GO:0022413 ! reproductive process in single-celled organism + +[Term] +id: GO:0007534 +name: gene conversion at mating-type locus +namespace: biological_process +def: "The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged." [GOC:elh, PMID:9928492] +is_a: GO:0006312 ! mitotic recombination +is_a: GO:0022414 ! reproductive process +is_a: GO:0035822 ! gene conversion +relationship: part_of GO:0007533 ! mating type switching + +[Term] +id: GO:0007535 +name: donor selection +namespace: biological_process +def: "The process that determines which donor locus a cell uses, in preference to another, in mating type switching." [GOC:mah, PMID:9928492] +synonym: "donor preference" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0007533 ! mating type switching + +[Term] +id: GO:0007536 +name: activation of recombination (HML) +namespace: biological_process +def: "The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492] +is_a: GO:0007535 ! donor selection +is_a: GO:0045911 ! positive regulation of DNA recombination + +[Term] +id: GO:0007537 +name: inactivation of recombination (HML) +namespace: biological_process +def: "The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492] +is_a: GO:0007535 ! donor selection +is_a: GO:0045910 ! negative regulation of DNA recombination + +[Term] +id: GO:0007538 +name: primary sex determination +namespace: biological_process +def: "The sex determination process that results in the initial specification of sexual status of an individual organism." [GOC:mah] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007539 +name: primary sex determination, soma +namespace: biological_process +def: "The transmission of information about sexual status from the initial, general, determination to signals specific to the soma." [GOC:ems] +is_a: GO:0007538 ! primary sex determination +relationship: part_of GO:0018993 ! somatic sex determination + +[Term] +id: GO:0007540 +name: sex determination, establishment of X:A ratio +namespace: biological_process +def: "The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it." [GOC:isa_complete, GOC:mr, PMID:20622855, Wikipedia:XY_sex-determination_system] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0007539 ! primary sex determination, soma +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0007541 +name: sex determination, primary response to X:A ratio +namespace: biological_process +def: "The developmental process in which an organism interprets its X to autosomal chromosomal complement." [GOC:isa_complete] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0007539 ! primary sex determination, soma + +[Term] +id: GO:0007542 +name: primary sex determination, germ-line +namespace: biological_process +def: "The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line." [GOC:ems] +is_a: GO:0007538 ! primary sex determination +relationship: part_of GO:0018992 ! germ-line sex determination + +[Term] +id: GO:0007543 +name: sex determination, somatic-gonadal interaction +namespace: biological_process +def: "The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism." [GOC:isa_complete] +synonym: "sex determination, somatic/gonadal interaction" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007542 ! primary sex determination, germ-line + +[Term] +id: GO:0007545 +name: processes downstream of sex determination signal +namespace: biological_process +def: "The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways." [GOC:mah] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007546 +name: somatic processes downstream of sex determination signal +namespace: biological_process +def: "The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways." [GOC:ems] +is_a: GO:0007545 ! processes downstream of sex determination signal + +[Term] +id: GO:0007547 +name: germ-line processes downstream of sex determination signal +namespace: biological_process +def: "The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways." [GOC:ems] +is_a: GO:0007545 ! processes downstream of sex determination signal +relationship: part_of GO:0018992 ! germ-line sex determination + +[Term] +id: GO:0007548 +name: sex differentiation +namespace: biological_process +def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai] +xref: Wikipedia:Sexual_differentiation +is_a: GO:0003006 ! developmental process involved in reproduction + +[Term] +id: GO:0007549 +name: dosage compensation +namespace: biological_process +def: "Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes." [GOC:ems, ISBN:0140512888, PMID:11498577] +xref: Wikipedia:Dosage_compensation +is_a: GO:0040029 ! regulation of gene expression, epigenetic + +[Term] +id: GO:0007550 +name: obsolete establishment of dosage compensation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:isa_complete] +comment: This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms. +synonym: "establishment of dosage compensation" EXACT [] +is_obsolete: true +consider: GO:0007549 + +[Term] +id: GO:0007551 +name: obsolete maintenance of dosage compensation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:isa_complete] +comment: This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms. +synonym: "maintenance of dosage compensation" EXACT [] +is_obsolete: true +consider: GO:0007549 + +[Term] +id: GO:0007552 +name: metamorphosis +namespace: biological_process +alt_id: GO:0046698 +alt_id: GO:0046699 +def: "A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster." [GOC:sensu, ISBN:0198506732, ISBN:0721662544] +xref: Wikipedia:Metamorphosis +is_a: GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007553 +name: regulation of ecdysteroid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732] +synonym: "regulation of ecdysteroid metabolism" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045455 ! ecdysteroid metabolic process +relationship: regulates GO:0045455 ! ecdysteroid metabolic process + +[Term] +id: GO:0007554 +name: regulation of ecdysteroid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] +synonym: "regulation of ecdysteroid anabolism" EXACT [] +synonym: "regulation of ecdysteroid biosynthesis" EXACT [] +synonym: "regulation of ecdysteroid formation" EXACT [] +synonym: "regulation of ecdysteroid synthesis" EXACT [] +is_a: GO:0007553 ! regulation of ecdysteroid metabolic process +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045456 ! ecdysteroid biosynthetic process +relationship: regulates GO:0045456 ! ecdysteroid biosynthetic process + +[Term] +id: GO:0007555 +name: regulation of ecdysteroid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell." [GOC:go_curators] +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045457 ! ecdysteroid secretion +relationship: regulates GO:0045457 ! ecdysteroid secretion + +[Term] +id: GO:0007556 +name: regulation of juvenile hormone metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] +synonym: "regulation of juvenile hormone metabolism" EXACT [] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006716 ! juvenile hormone metabolic process +relationship: part_of GO:0002165 ! instar larval or pupal development +relationship: regulates GO:0006716 ! juvenile hormone metabolic process + +[Term] +id: GO:0007557 +name: regulation of juvenile hormone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] +synonym: "regulation of juvenile hormone anabolism" EXACT [] +synonym: "regulation of juvenile hormone biosynthesis" EXACT [] +synonym: "regulation of juvenile hormone formation" EXACT [] +synonym: "regulation of juvenile hormone synthesis" EXACT [] +is_a: GO:0007556 ! regulation of juvenile hormone metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006718 ! juvenile hormone biosynthetic process +relationship: regulates GO:0006718 ! juvenile hormone biosynthetic process + +[Term] +id: GO:0007558 +name: regulation of juvenile hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of juvenile hormone secretion." [GOC:go_curators] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045443 ! juvenile hormone secretion +relationship: regulates GO:0045443 ! juvenile hormone secretion + +[Term] +id: GO:0007559 +name: obsolete histolysis +namespace: biological_process +def: "OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue." [GOC:dph, GOC:ma] +comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants. +xref: Wikipedia:Histolysis +is_obsolete: true +consider: GO:0008219 +consider: GO:0012501 + +[Term] +id: GO:0007560 +name: imaginal disc morphogenesis +namespace: biological_process +alt_id: GO:0007452 +def: "The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:jid] +synonym: "imaginal disc metamorphosis" EXACT [] +is_a: GO:0048563 ! post-embryonic animal organ morphogenesis +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0007444 ! imaginal disc development +relationship: part_of GO:0007552 ! metamorphosis +relationship: part_of GO:0048707 ! instar larval or pupal morphogenesis + +[Term] +id: GO:0007561 +name: imaginal disc eversion +namespace: biological_process +def: "The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis." [PMID:11494317] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007560 ! imaginal disc morphogenesis + +[Term] +id: GO:0007562 +name: eclosion +namespace: biological_process +def: "The emergence of an adult insect from a pupa case." [GOC:dgh, GOC:dos, GOC:mah, ISBN:0198600461] +xref: Wikipedia:Pupa#Emergence +is_a: GO:0071684 ! organism emergence from protective structure +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0007563 +name: regulation of eclosion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg." [GOC:go_curators, ISBN:0198600461] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007562 ! eclosion +relationship: regulates GO:0007562 ! eclosion + +[Term] +id: GO:0007564 +name: regulation of chitin-based cuticle tanning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning." [GOC:go_curators, GOC:jid, GOC:mtg_sensu] +synonym: "regulation of cuticle hardening" NARROW [] +synonym: "regulation of cuticle tanning" EXACT [] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007593 ! chitin-based cuticle sclerotization +relationship: regulates GO:0007593 ! chitin-based cuticle sclerotization + +[Term] +id: GO:0007565 +name: female pregnancy +namespace: biological_process +def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825] +subset: goslim_chembl +synonym: "carrying of young" RELATED [] +synonym: "gestation" EXACT [] +xref: Wikipedia:Gestation +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process + +[Term] +id: GO:0007566 +name: embryo implantation +namespace: biological_process +def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, http://www.medterms.com] +synonym: "blastocyst implantation" EXACT [] +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007275 ! multicellular organism development +relationship: part_of GO:0007565 ! female pregnancy + +[Term] +id: GO:0007567 +name: parturition +namespace: biological_process +def: "The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs." [ISBN:0198506732] +synonym: "egg laying" NARROW [] +synonym: "giving birth" EXACT [] +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process + +[Term] +id: GO:0007568 +name: aging +namespace: biological_process +alt_id: GO:0016280 +def: "A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] +subset: goslim_chembl +subset: goslim_generic +synonym: "ageing" EXACT [] +xref: Wikipedia:Aging +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0007569 +name: cell aging +namespace: biological_process +def: "An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469)." [GOC:PO_curators] +synonym: "cell ageing" EXACT [] +is_a: GO:0007568 ! aging +is_a: GO:0048869 ! cellular developmental process + +[Term] +id: GO:0007570 +name: obsolete age dependent accumulation of genetic damage +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "age dependent accumulation of genetic damage" EXACT [] +is_obsolete: true +consider: GO:0001301 + +[Term] +id: GO:0007571 +name: age-dependent general metabolic decline +namespace: biological_process +def: "A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis." [GOC:jh, GOC:mah, PMID:9891807] +synonym: "age-dependent decreased translational activity" NARROW [] +synonym: "age-dependent increased protein content" NARROW [] +synonym: "age-dependent yeast cell size increase" RELATED [] +synonym: "nucleolar size increase" NARROW [] +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0007568 ! aging + +[Term] +id: GO:0007572 +name: obsolete age dependent decreased translational activity +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "age dependent decreased translational activity" EXACT [] +is_obsolete: true +consider: GO:0007571 + +[Term] +id: GO:0007573 +name: obsolete age dependent increased protein content +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "age dependent increased protein content" EXACT [] +is_obsolete: true +consider: GO:0007571 + +[Term] +id: GO:0007574 +name: obsolete cell aging (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell." [GOC:sgd_curators] +comment: This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'. +synonym: "cell aging (sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0007569 + +[Term] +id: GO:0007575 +name: obsolete nucleolar size increase +namespace: biological_process +def: "OBSOLETE. The process of nucleolar expansion." [GOC:ai] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "nucleolar size increase" EXACT [] +is_obsolete: true +consider: GO:0007571 +consider: GO:0007576 + +[Term] +id: GO:0007576 +name: nucleolar fragmentation +namespace: biological_process +alt_id: GO:0046616 +def: "The cell aging process that results in the nucleolus breaking down into fragments." [GOC:mah, PMID:9271578] +synonym: "nucleolar size increase" RELATED [] +is_a: GO:0007000 ! nucleolus organization +relationship: part_of GO:0007569 ! cell aging + +[Term] +id: GO:0007577 +name: obsolete autophagic death (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA." [GOC:sgd_curators] +comment: This term was made obsolete because a more correct term has been created. +synonym: "autophagic death (sensu Saccharomyces)" EXACT [] +is_obsolete: true +consider: GO:0048102 + +[Term] +id: GO:0007578 +name: obsolete aging dependent sterility (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes." [GOC:sgd_curators] +comment: This term was made obsolete because it reflected a trait or phenotype. +synonym: "aging dependent sterility (sensu Saccharomyces)" EXACT [] +is_obsolete: true +consider: GO:0030466 + +[Term] +id: GO:0007579 +name: obsolete senescence factor accumulation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jh] +comment: This term was made obsolete because it does not represent a process. +synonym: "senescence factor accumulation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007580 +name: extrachromosomal circular DNA accumulation involved in cell aging +namespace: biological_process +def: "Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication." [GOC:jh, PMID:9891807] +comment: Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy. +synonym: "extrachromosomal circular DNA accumulation during cell ageing" RELATED [] +synonym: "extrachromosomal circular DNA accumulation during cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001301 ! progressive alteration of chromatin involved in cell aging + +[Term] +id: GO:0007581 +name: obsolete age-dependent yeast cell size increase +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:sgd_curators] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "age-dependent yeast cell size increase" EXACT [] +is_obsolete: true +consider: GO:0007571 + +[Term] +id: GO:0007583 +name: obsolete killer activity +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it is ambiguous; 'killer activity' could refer to several different processes. +synonym: "killer activity" EXACT [] +is_obsolete: true +consider: GO:0042267 + +[Term] +id: GO:0007584 +name: response to nutrient +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus." [GOC:go_curators] +synonym: "nutritional response pathway" NARROW [] +synonym: "response to nutrients" EXACT [] +is_a: GO:0031667 ! response to nutrient levels +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0007585 +name: respiratory gaseous exchange by respiratory system +namespace: biological_process +def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732] +subset: goslim_chembl +synonym: "breathing" BROAD [] +synonym: "respiration" BROAD [] +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0007586 +name: digestion +namespace: biological_process +def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_pir +xref: Wikipedia:Digestion +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0007588 +name: excretion +namespace: biological_process +def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023] +subset: goslim_pir +xref: Wikipedia:Excretion +is_a: GO:0003008 ! system process + +[Term] +id: GO:0007589 +name: body fluid secretion +namespace: biological_process +def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0046903 ! secretion +is_a: GO:0050878 ! regulation of body fluid levels + +[Term] +id: GO:0007590 +name: obsolete fat body metabolic process (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557)." [GOC:go_curators, ISBN:0198506732] +comment: This term was made obsolete because it represents metabolism within the fat body not of the fat body. +synonym: "fat body metabolic process (sensu Insecta)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0007591 +name: molting cycle, chitin-based cuticle +namespace: biological_process +def: "The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster." [GOC:jl, GOC:mtg_sensu] +synonym: "chitin-based cuticle molting cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042303 ! molting cycle + +[Term] +id: GO:0007592 +name: obsolete protein-based cuticle development +namespace: biological_process +def: "OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans." [GOC:ems, GOC:mtg_sensu] +comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term. +synonym: "protein-based cuticle anabolism" EXACT [] +synonym: "protein-based cuticle biosynthetic process" EXACT [] +synonym: "protein-based cuticle development" EXACT [] +synonym: "protein-based cuticle formation" EXACT [] +synonym: "protein-based cuticle synthesis" EXACT [] +is_obsolete: true +consider: GO:0040002 +consider: GO:0040003 + +[Term] +id: GO:0007593 +name: chitin-based cuticle sclerotization +namespace: biological_process +alt_id: GO:0045452 +def: "The process of hardening of a chitin-based cuticle." [GOC:dos, GOC:mtg_sensu] +synonym: "chitin-based cuticle tanning" RELATED [GOC:bf, GOC:dos, GOC:sart] +synonym: "cuticle hardening" NARROW [] +is_a: GO:0007591 ! molting cycle, chitin-based cuticle +is_a: GO:0021700 ! developmental maturation +is_a: GO:0022404 ! molting cycle process + +[Term] +id: GO:0007594 +name: puparial adhesion +namespace: biological_process +def: "The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation." [GOC:ma] +synonym: "puparial glue" RELATED [] +is_a: GO:0022609 ! multicellular organism adhesion to substrate +relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle + +[Term] +id: GO:0007595 +name: lactation +namespace: biological_process +def: "The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young." [ISBN:0198506732] +synonym: "milk secretion" EXACT [GOC:pr] +xref: Wikipedia:Lactation +is_a: GO:0007589 ! body fluid secretion +relationship: has_part GO:0060156 ! milk ejection reflex +relationship: part_of GO:0030879 ! mammary gland development + +[Term] +id: GO:0007596 +name: blood coagulation +namespace: biological_process +def: "The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers." [http://www.graylab.ac.uk/omd/, ISBN:0198506732] +synonym: "blood clotting" EXACT [] +xref: Wikipedia:Coagulation +is_a: GO:0007599 ! hemostasis +is_a: GO:0050817 ! coagulation +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0007597 +name: blood coagulation, intrinsic pathway +namespace: biological_process +def: "A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X." [GOC:add, GOC:mah, GOC:pde] +comment: See also the biological process term 'blood coagulation, extrinsic pathway ; GO:0007598'. +is_a: GO:0072376 ! protein activation cascade +relationship: part_of GO:0072378 ! blood coagulation, fibrin clot formation + +[Term] +id: GO:0007598 +name: blood coagulation, extrinsic pathway +namespace: biological_process +def: "A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X." [GOC:add, GOC:mah, GOC:pde] +comment: See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'. +is_a: GO:0072376 ! protein activation cascade +relationship: part_of GO:0072378 ! blood coagulation, fibrin clot formation + +[Term] +id: GO:0007599 +name: hemostasis +namespace: biological_process +def: "The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part." [ISBN:0198506732] +xref: Wikipedia:Hemostasis +is_a: GO:0050878 ! regulation of body fluid levels + +[Term] +id: GO:0007600 +name: sensory perception +namespace: biological_process +def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph] +subset: goslim_drosophila +xref: Wikipedia:Perception +is_a: GO:0050877 ! nervous system process + +[Term] +id: GO:0007601 +name: visual perception +namespace: biological_process +def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai] +synonym: "sense of sight" EXACT [] +synonym: "sensory visual perception" EXACT [] +synonym: "vision" EXACT [] +xref: Wikipedia:Visual_perception +is_a: GO:0050953 ! sensory perception of light stimulus + +[Term] +id: GO:0007602 +name: phototransduction +namespace: biological_process +def: "The sequence of reactions within a cell required to convert absorbed photons into a molecular signal." [GOC:go_curators] +synonym: "opsin" RELATED [] +synonym: "phototransduction, visible light, light adaptation" NARROW [] +synonym: "phototrophin mediated phototransduction" NARROW [] +xref: Wikipedia:Visual_phototransduction +is_a: GO:0007165 ! signal transduction +is_a: GO:0009583 ! detection of light stimulus + +[Term] +id: GO:0007603 +name: phototransduction, visible light +namespace: biological_process +def: "The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] +synonym: "visual cascade" EXACT [PMID:1962207, PMID:9822721] +synonym: "visual transduction" EXACT [PMID:10611962] +is_a: GO:0007602 ! phototransduction +is_a: GO:0009584 ! detection of visible light + +[Term] +id: GO:0007604 +name: phototransduction, UV +namespace: biological_process +def: "The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers." [GOC:go_curators, ISBN:0198506732] +synonym: "phototransduction, ultraviolet light" EXACT [] +synonym: "phototransduction, ultraviolet radiation" EXACT [] +synonym: "phototransduction, UV light" EXACT [] +synonym: "phototransduction, UV radiation" EXACT [] +synonym: "UV-sensitive opsin" RELATED [] +is_a: GO:0007602 ! phototransduction +is_a: GO:0009589 ! detection of UV +is_a: GO:0034644 ! cellular response to UV + +[Term] +id: GO:0007605 +name: sensory perception of sound +namespace: biological_process +def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai] +synonym: "hearing" EXACT [] +synonym: "perception of sound" EXACT [] +xref: Wikipedia:Hearing_(sense) +is_a: GO:0050954 ! sensory perception of mechanical stimulus + +[Term] +id: GO:0007606 +name: sensory perception of chemical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "chemosensory perception" EXACT [] +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0007607 +name: obsolete taste perception +namespace: biological_process +def: "OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal." [GOC:jl, ISBN:0395825172] +comment: This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage. +synonym: "taste perception" EXACT [] +is_obsolete: true +consider: GO:0050909 +consider: GO:0050912 + +[Term] +id: GO:0007608 +name: sensory perception of smell +namespace: biological_process +def: "The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process." [GOC:ai] +synonym: "olfaction" EXACT [] +synonym: "scent perception" EXACT [] +synonym: "sense of smell" EXACT [] +synonym: "smell perception" EXACT [] +xref: Wikipedia:Olfaction +is_a: GO:0007606 ! sensory perception of chemical stimulus + +[Term] +id: GO:0007610 +name: behavior +namespace: biological_process +alt_id: GO:0023032 +alt_id: GO:0044708 +alt_id: GO:0044709 +def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] +comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). +subset: gocheck_do_not_manually_annotate +subset: goslim_agr +subset: goslim_flybase_ribbon +synonym: "behavioral response to stimulus" EXACT [] +synonym: "behaviour" EXACT [] +synonym: "behavioural response to stimulus" EXACT [] +synonym: "single-organism behavior" RELATED [] +xref: Wikipedia:Behavior +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0032502 ! developmental process +created_by: jl +creation_date: 2012-09-20T14:06:08Z + +[Term] +id: GO:0007611 +name: learning or memory +namespace: biological_process +def: "The acquisition and processing of information and/or the storage and retrieval of this information over time." [GOC:jid, PMID:8938125] +is_a: GO:0007610 ! behavior +is_a: GO:0050890 ! cognition + +[Term] +id: GO:0007612 +name: learning +namespace: biological_process +def: "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience." [ISBN:0582227089, ISBN:0721662544] +xref: Wikipedia:Learning +is_a: GO:0007611 ! learning or memory + +[Term] +id: GO:0007613 +name: memory +namespace: biological_process +def: "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." [GOC:curators, ISBN:0582227089] +xref: Wikipedia:Memory +is_a: GO:0007611 ! learning or memory + +[Term] +id: GO:0007614 +name: short-term memory +namespace: biological_process +def: "The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089] +xref: Wikipedia:Short-term_memory +is_a: GO:0007613 ! memory + +[Term] +id: GO:0007615 +name: anesthesia-resistant memory +namespace: biological_process +def: "The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis." [PMID:15143285, PMID:17088531] +is_a: GO:0007613 ! memory + +[Term] +id: GO:0007616 +name: long-term memory +namespace: biological_process +def: "The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089] +xref: Wikipedia:Long-term_memory +is_a: GO:0007613 ! memory + +[Term] +id: GO:0007617 +name: mating behavior +namespace: biological_process +def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph] +synonym: "mating behaviour" EXACT [] +xref: Wikipedia:Mating_behaviour +is_a: GO:0019098 ! reproductive behavior +intersection_of: GO:0007610 ! behavior +intersection_of: part_of GO:0007618 ! mating +relationship: part_of GO:0007618 ! mating + +[Term] +id: GO:0007618 +name: mating +namespace: biological_process +def: "The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes." [GOC:jl, ISBN:0387520546] +is_a: GO:0044703 ! multi-organism reproductive process +relationship: part_of GO:0019953 ! sexual reproduction + +[Term] +id: GO:0007619 +name: courtship behavior +namespace: biological_process +def: "The behavior of an organism for the purpose of attracting sexual partners." [GOC:ai, GOC:dph] +synonym: "courtship behaviour" EXACT [] +is_a: GO:0007617 ! mating behavior + +[Term] +id: GO:0007620 +name: copulation +namespace: biological_process +def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544] +is_a: GO:0007618 ! mating + +[Term] +id: GO:0007621 +name: negative regulation of female receptivity +namespace: biological_process +def: "Any process that stops, prevents or reduces the receptiveness of a female to male advances." [GOC:bf, PMID:11092827] +synonym: "down regulation of female receptivity" EXACT [] +synonym: "down-regulation of female receptivity" EXACT [] +synonym: "downregulation of female receptivity" EXACT [] +synonym: "inhibition of female receptivity" NARROW [] +is_a: GO:0045924 ! regulation of female receptivity + +[Term] +id: GO:0007622 +name: rhythmic behavior +namespace: biological_process +def: "The specific behavior of an organism that recur with measured regularity." [GOC:jl, GOC:pr] +synonym: "rhythmic behavioral response to stimulus" EXACT [] +synonym: "rhythmic behaviour" EXACT [] +synonym: "rhythmic behavioural response to stimulus" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0048511 ! rhythmic process + +[Term] +id: GO:0007623 +name: circadian rhythm +namespace: biological_process +alt_id: GO:0050895 +def: "Any biological process in an organism that recurs with a regularity of approximately 24 hours." [GOC:bf, GOC:go_curators] +subset: goslim_drosophila +subset: goslim_plant +synonym: "circadian process" EXACT [] +synonym: "circadian response" RELATED [] +synonym: "response to circadian rhythm" RELATED [] +xref: Wikipedia:Circadian_rhythm +is_a: GO:0048511 ! rhythmic process + +[Term] +id: GO:0007624 +name: ultradian rhythm +namespace: biological_process +def: "The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours." [GOC:jl, PMID:19708721] +is_a: GO:0048511 ! rhythmic process + +[Term] +id: GO:0007625 +name: grooming behavior +namespace: biological_process +def: "The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites." [GOC:jl, GOC:pr] +synonym: "grooming behaviour" EXACT [] +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0007626 +name: locomotory behavior +namespace: biological_process +def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] +subset: goslim_drosophila +synonym: "behavior via locomotion" EXACT [] +synonym: "locomotion in response to stimulus" EXACT [] +synonym: "locomotory behavioral response to stimulus" EXACT [] +synonym: "locomotory behaviour" EXACT [] +synonym: "locomotory behavioural response to stimulus" EXACT [] +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0007627 +name: obsolete larval behavior (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects." [GOC:ai, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "larval behavior (sensu Insecta)" EXACT [] +is_obsolete: true +replaced_by: GO:0030537 + +[Term] +id: GO:0007628 +name: adult walking behavior +namespace: biological_process +def: "The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg." [GOC:jid, GOC:pr, ISBN:0198606907] +synonym: "adult walking behaviour" EXACT [] +is_a: GO:0008344 ! adult locomotory behavior +is_a: GO:0090659 ! walking behavior + +[Term] +id: GO:0007629 +name: flight behavior +namespace: biological_process +def: "The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air." [GOC:jid, ISBN:0198606907] +synonym: "flight behaviour" EXACT [] +is_a: GO:0008344 ! adult locomotory behavior + +[Term] +id: GO:0007630 +name: jump response +namespace: biological_process +def: "The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus." [GOC:jid, ISBN:0198606907] +is_a: GO:0008344 ! adult locomotory behavior + +[Term] +id: GO:0007631 +name: feeding behavior +namespace: biological_process +alt_id: GO:0044366 +alt_id: GO:0044367 +alt_id: GO:0044368 +alt_id: GO:0044369 +alt_id: GO:0044370 +alt_id: GO:0044371 +alt_id: GO:0044372 +def: "Behavior associated with the intake of food." [GOC:mah] +comment: See also the biological process term 'behavior ; GO:0007610'. +synonym: "behavioral response to food" EXACT [] +synonym: "behavioural response to food" EXACT [] +synonym: "eating" NARROW [] +synonym: "feeding behaviour" EXACT [] +synonym: "feeding from phloem of other organism" NARROW [] +synonym: "feeding from plant phloem" NARROW [] +synonym: "feeding from tissue of other organism" NARROW [] +synonym: "feeding from vascular tissue of another organism" NARROW [] +synonym: "feeding from xylem of other organism" NARROW [] +synonym: "feeding on blood of other organism" NARROW [] +synonym: "feeding on or from other organism" NARROW [] +synonym: "feeding on plant sap" NARROW [] +synonym: "hematophagy" NARROW [] +synonym: "injection of substance into other organism during feeding on blood of other organism" NARROW [] +synonym: "taking of blood meal" NARROW [] +xref: Wikipedia:List_of_feeding_behaviours +is_a: GO:0007610 ! behavior +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18547 xsd:anyURI +created_by: jl +creation_date: 2011-10-27T03:53:33Z + +[Term] +id: GO:0007632 +name: visual behavior +namespace: biological_process +def: "The behavior of an organism in response to a visual stimulus." [GOC:jid, GOC:pr] +synonym: "behavioral response to visual stimulus" EXACT [] +synonym: "behavioural response to visual stimulus" EXACT [] +synonym: "visual behaviour" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0009416 ! response to light stimulus +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0007633 +name: pattern orientation +namespace: biological_process +def: "The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes." [GOC:jid, PMID:9933535] +synonym: "behavioral response to pattern orientation" EXACT [] +synonym: "behavioural response to pattern orientation" EXACT [] +is_a: GO:0007632 ! visual behavior + +[Term] +id: GO:0007634 +name: optokinetic behavior +namespace: biological_process +def: "The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus." [GOC:jid, GOC:pr, http://www.mercksource.com] +synonym: "optokinetic behaviour" EXACT [] +is_a: GO:0007632 ! visual behavior + +[Term] +id: GO:0007635 +name: chemosensory behavior +namespace: biological_process +def: "Behavior that is dependent upon the sensation of chemicals." [GOC:go_curators] +synonym: "behavioral response to chemical stimulus" EXACT [] +synonym: "behavioural response to chemical stimulus" EXACT [] +synonym: "chemosensory behaviour" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0007636 +name: chemosensory jump behavior +namespace: biological_process +def: "The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance." [GOC:jid] +synonym: "chemosensory jump behaviour" EXACT [] +synonym: "jump response to chemical stimulus" EXACT [] +is_a: GO:0007630 ! jump response +is_a: GO:0007635 ! chemosensory behavior + +[Term] +id: GO:0007637 +name: proboscis extension reflex +namespace: biological_process +def: "The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus." [FB:FBrf0044924, GOC:jid] +synonym: "behavioral response to nutritional stimulus, proboscis extension" EXACT [] +synonym: "proboscis extension in response to nutritional stimulus" EXACT [] +is_a: GO:0007635 ! chemosensory behavior +is_a: GO:0051780 ! behavioral response to nutrient +is_a: GO:0060004 ! reflex + +[Term] +id: GO:0007638 +name: mechanosensory behavior +namespace: biological_process +def: "Behavior that is dependent upon the sensation of a mechanical stimulus." [GOC:go_curators] +synonym: "behavioral response to mechanical stimulus" EXACT [] +synonym: "behavioural response to mechanical stimulus" EXACT [] +synonym: "mechanosensory behaviour" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0009612 ! response to mechanical stimulus + +[Term] +id: GO:0007639 +name: homeostasis of number of meristem cells +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem." [GOC:isa_complete] +is_a: GO:0010075 ! regulation of meristem growth +is_a: GO:0048873 ! homeostasis of number of cells within a tissue + +[Term] +id: GO:0008001 +name: obsolete fibrinogen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it does not describe an activity. +synonym: "fibrinogen" EXACT [] +is_obsolete: true +replaced_by: GO:0005577 + +[Term] +id: GO:0008002 +name: obsolete lamina lucida +namespace: cellular_component +def: "OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina." [ISBN:0815316194] +comment: This term was made obsolete because it is thought to be an experimental artefact. +xref: Wikipedia:Lamina_lucida +is_obsolete: true + +[Term] +id: GO:0008004 +name: obsolete lamina reticularis +namespace: cellular_component +def: "OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue." [ISBN:0815316194] +comment: This term was obsoleted because as a layer of the basement membrane, the lamina reticularis is thought to be an artefact. See PMID:24137544 and PMID:8061357. +is_obsolete: true +replaced_by: GO:0005604 + +[Term] +id: GO:0008008 +name: obsolete membrane attack complex protein beta2 chain +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "membrane attack complex protein beta2 chain" EXACT [] +is_obsolete: true +replaced_by: GO:0005579 + +[Term] +id: GO:0008009 +name: chemokine activity +namespace: molecular_function +def: "The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, PMID:12183377, Wikipedia:Chemokine] +subset: goslim_chembl +is_a: GO:0005125 ! cytokine activity +is_a: GO:0042379 ! chemokine receptor binding +relationship: part_of GO:0060326 ! cell chemotaxis + +[Term] +id: GO:0008010 +name: structural constituent of chitin-based larval cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +synonym: "structural constituent of larval cuticle" BROAD [] +is_a: GO:0005214 ! structural constituent of chitin-based cuticle + +[Term] +id: GO:0008011 +name: structural constituent of pupal chitin-based cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +synonym: "structural constituent of pupal cuticle" BROAD [] +is_a: GO:0005214 ! structural constituent of chitin-based cuticle + +[Term] +id: GO:0008012 +name: structural constituent of adult chitin-based cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] +synonym: "structural constituent of adult cuticle" BROAD [] +is_a: GO:0005214 ! structural constituent of chitin-based cuticle + +[Term] +id: GO:0008013 +name: beta-catenin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the beta subunit of the catenin complex." [GOC:bf] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0008014 +name: obsolete calcium-dependent cell adhesion molecule activity +namespace: molecular_function +alt_id: GO:0001538 +def: "OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "cadherin" NARROW [] +synonym: "calcium-dependent cell adhesion molecule activity" EXACT [] +is_obsolete: true +consider: GO:0005515 +consider: GO:0016021 +consider: GO:0016339 + +[Term] +id: GO:0008015 +name: blood circulation +namespace: biological_process +alt_id: GO:0070261 +def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825] +subset: goslim_pir +synonym: "hemolymph circulation" RELATED [] +is_a: GO:0003013 ! circulatory system process + +[Term] +id: GO:0008016 +name: regulation of heart contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "regulation of cardiac contraction" EXACT [] +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060047 ! heart contraction +relationship: regulates GO:0060047 ! heart contraction + +[Term] +id: GO:0008017 +name: microtubule binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers." [GOC:krc] +synonym: "microtubule severing activity" RELATED [] +synonym: "microtubule/chromatin interaction" RELATED [] +is_a: GO:0015631 ! tubulin binding + +[Term] +id: GO:0008018 +name: obsolete structural protein of chorion (sensu Drosophila) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the function is covered by a parent term. +synonym: "structural protein of chorion (sensu Drosophila)" EXACT [] +is_obsolete: true +replaced_by: GO:0005213 + +[Term] +id: GO:0008019 +name: obsolete macrophage receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because its name is ambiguous, and it was never defined. +synonym: "macrophage receptor activity" EXACT [] +is_obsolete: true +consider: GO:0005044 +consider: GO:0038187 + +[Term] +id: GO:0008020 +name: G protein-coupled photoreceptor activity +namespace: molecular_function +alt_id: GO:0004975 +def: "Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph, ISBN:0198506732] +synonym: "G protein coupled photoreceptor activity" EXACT [] +synonym: "G-protein coupled photoreceptor activity" EXACT [] +synonym: "photoreceptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0009881 ! photoreceptor activity +relationship: part_of GO:0009584 ! detection of visible light + +[Term] +id: GO:0008021 +name: synaptic vesicle +namespace: cellular_component +def: "A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." [PMID:10099709, PMID:12563290] +comment: This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles. +subset: goslim_synapse +synonym: "docked vesicle" NARROW [NIF_Subcellular:sao403156667] +xref: NIF_Subcellular:sao1071221672 +xref: Wikipedia:Synaptic_vesicle +is_a: GO:0070382 ! exocytic vesicle +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0008022 +name: protein C-terminus binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue." [ISBN:0198506732] +subset: goslim_chembl +synonym: "C-terminal binding" EXACT [] +synonym: "C-terminal end binding" EXACT [GOC:sl] +synonym: "carboxy-terminal binding" RELATED [GOC:jsg] +synonym: "carboxy-terminus binding" RELATED [GOC:sl] +synonym: "carboxyl-terminal binding" RELATED [GOC:jsg] +synonym: "carboxyl-terminus binding" RELATED [GOC:sl] +synonym: "carboxylate-terminal binding" RELATED [GOC:jsg] +synonym: "carboxylate-terminus binding" NARROW [GOC:jsg] +synonym: "COOH-terminal binding" NARROW [GOC:jsg] +synonym: "COOH-terminus binding" NARROW [GOC:jsg, GOC:sl] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0008023 +name: transcription elongation factor complex +namespace: cellular_component +def: "Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation." [GOC:jl] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0008024 +name: cyclin/CDK positive transcription elongation factor complex +namespace: cellular_component +def: "A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit." [GOC:bhm, GOC:vw, PMID:10766736, PMID:16721054, PMID:17079683, PMID:19328067, PMID:7759473] +comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'. +synonym: "positive transcription elongation factor complex b" RELATED [] +is_a: GO:0008023 ! transcription elongation factor complex +is_a: GO:0019908 ! nuclear cyclin-dependent protein kinase holoenzyme complex +is_a: GO:0032806 ! carboxy-terminal domain protein kinase complex + +[Term] +id: GO:0008025 +name: obsolete diazepam binding inhibitor activity +namespace: molecular_function +def: "OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters." [ISBN:0198506732, PMID:11883709] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "DBI" EXACT [] +synonym: "diazepam binding inhibitor activity" EXACT [] +synonym: "diazepam-binding inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0004857 +consider: GO:0030156 +consider: GO:0050796 +consider: GO:0050809 +consider: GO:0050810 +consider: GO:0050811 +consider: GO:0050812 + +[Term] +id: GO:0008028 +name: monocarboxylic acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0008505 +def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] +synonym: "monocarboxylate carrier" NARROW [] +synonym: "prostaglandin/thromboxane transporter activity" NARROW [] +xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol" +xref: Reactome:R-HSA-433698 "SLC16A1,3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +relationship: part_of GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0008029 +name: pentraxin receptor activity +namespace: molecular_function +def: "Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +comment: Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP). +synonym: "pentaxin receptor" EXACT [] +is_a: GO:0001847 ! opsonin receptor activity +relationship: has_part GO:0001864 ! pentraxin binding + +[Term] +id: GO:0008030 +name: neuronal pentraxin receptor activity +namespace: molecular_function +def: "Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling, PMID:18840757] +synonym: "neuronal pentaxin receptor" EXACT [] +is_a: GO:0008029 ! pentraxin receptor activity + +[Term] +id: GO:0008031 +name: eclosion hormone activity +namespace: molecular_function +def: "The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis." [GOC:mah, ISBN:0198506732] +is_a: GO:0005184 ! neuropeptide hormone activity + +[Term] +id: GO:0008033 +name: tRNA processing +namespace: biological_process +def: "The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group." [GOC:jl, PMID:12533506] +subset: goslim_yeast +synonym: "tRNA maturation" EXACT [GOC:vw] +is_a: GO:0006399 ! tRNA metabolic process +is_a: GO:0034470 ! ncRNA processing + +[Term] +id: GO:0008034 +name: obsolete lipoprotein binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because its text definition and implicit ontology-structure definition disagreed, and as a result the term had been used in annotations with more than one meaning. +synonym: "lipoprotein binding" EXACT [] +is_obsolete: true +consider: GO:0071723 +consider: GO:0071813 + +[Term] +id: GO:0008035 +name: high-density lipoprotein particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE." [GOC:mah] +synonym: "HDL binding" EXACT [GOC:mah] +is_a: GO:0071813 ! lipoprotein particle binding + +[Term] +id: GO:0008036 +name: diuretic hormone receptor activity +namespace: molecular_function +def: "Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity." [GOC:ai, GOC:signaling] +is_a: GO:0038023 ! signaling receptor activity +relationship: part_of GO:0009755 ! hormone-mediated signaling pathway + +[Term] +id: GO:0008037 +name: cell recognition +namespace: biological_process +def: "The process in which a cell in an organism interprets its surroundings." [GOC:go_curators] +subset: goslim_pir +synonym: "recognition of surroundings by cell" EXACT [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0008038 +name: neuron recognition +namespace: biological_process +def: "The process in which a neuronal cell in a multicellular organism interprets its surroundings." [GOC:go_curators] +synonym: "neuronal cell recognition" EXACT [] +is_a: GO:0008037 ! cell recognition +relationship: part_of GO:0048666 ! neuron development + +[Term] +id: GO:0008039 +name: synaptic target recognition +namespace: biological_process +def: "The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses." [GOC:mah, ISBN:0878932437] +subset: goslim_synapse +synonym: "neuronal targeting" EXACT [] +is_a: GO:0008038 ! neuron recognition + +[Term] +id: GO:0008041 +name: obsolete storage protein of fat body (sensu Insecta) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it describes a cellular location rather than a function. +synonym: "storage protein of fat body (sensu Insecta)" EXACT [] +is_obsolete: true +replaced_by: GO:0045735 + +[Term] +id: GO:0008042 +name: obsolete iron-sulfur electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system." [GOC:kd] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "ferredoxin" NARROW [] +synonym: "iron-sulfur electron transfer carrier" EXACT [] +synonym: "iron-sulphur electron transfer carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0008043 +name: intracellular ferritin complex +namespace: cellular_component +def: "A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains." [GOC:jl, GOC:mah, PMID:19154717] +is_a: GO:0070288 ! ferritin complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0008044 +name: obsolete adult behavior (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects." [GOC:bf, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "adult behavior (sensu Insecta)" EXACT [] +is_obsolete: true +replaced_by: GO:0030534 + +[Term] +id: GO:0008045 +name: motor neuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues." [CL:0000100, GOC:pr, ISBN:0878932437] +synonym: "motoneuron axon guidance" EXACT [] +synonym: "motor axon guidance" EXACT [] +synonym: "motor axon pathfinding" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance + +[Term] +id: GO:0008046 +name: axon guidance receptor activity +namespace: molecular_function +def: "Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance." [GOC:dph, GOC:signaling, GOC:tb, PMID:15107857, PMID:15339666] +synonym: "receptor activity involved in axon guidance" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004888 ! transmembrane signaling receptor activity +intersection_of: GO:0004888 ! transmembrane signaling receptor activity +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance + +[Term] +id: GO:0008047 +name: enzyme activator activity +namespace: molecular_function +alt_id: GO:0010577 +def: "Binds to and increases the activity of an enzyme." [GOC:dph, GOC:mah, GOC:tb] +synonym: "metalloenzyme activator activity" NARROW [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0043085 ! positive regulation of catalytic activity + +[Term] +id: GO:0008048 +name: calcium sensitive guanylate cyclase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration." [GOC:mah] +is_a: GO:0030250 ! guanylate cyclase activator activity + +[Term] +id: GO:0008049 +name: male courtship behavior +namespace: biological_process +alt_id: GO:0016542 +def: "The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, GOC:pr] +synonym: "male courtship behaviour" EXACT [] +is_a: GO:0007619 ! courtship behavior +is_a: GO:0060179 ! male mating behavior + +[Term] +id: GO:0008050 +name: female courtship behavior +namespace: biological_process +def: "The behavior of a female, for the purpose of attracting a sexual partner." [GOC:bf, GOC:pr] +synonym: "female courtship behaviour" EXACT [] +is_a: GO:0007619 ! courtship behavior +is_a: GO:0060180 ! female mating behavior + +[Term] +id: GO:0008051 +name: obsolete farnesyl-diphosphate farnesyl transferase complex +namespace: cellular_component +def: "OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity." [GOC:mah] +comment: This term was made obsolete because there is no evidence that this enzyme ever exists as anything other than a monomer. +synonym: "farnesyl-diphosphate farnesyl transferase complex" EXACT [] +is_obsolete: true +consider: GO:0004310 + +[Term] +id: GO:0008052 +name: sensory organ boundary specification +namespace: biological_process +def: "The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained." [GO_REF:0000021] +synonym: "sense organ boundary specification" EXACT [GOC:dph] +is_a: GO:0010160 ! formation of animal organ boundary +relationship: part_of GO:0007423 ! sensory organ development + +[Term] +id: GO:0008053 +name: mitochondrial fusion +namespace: biological_process +def: "Merging of two or more mitochondria within a cell to form a single compartment." [PMID:11038192] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0048284 ! organelle fusion + +[Term] +id: GO:0008055 +name: ocellus pigment biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates." [GOC:ai, PMID:15176085, PMID:18421706] +synonym: "ocellus pigment anabolism" EXACT [] +synonym: "ocellus pigment biosynthesis" EXACT [] +synonym: "ocellus pigment formation" EXACT [] +synonym: "ocellus pigment synthesis" EXACT [] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0046158 ! ocellus pigment metabolic process + +[Term] +id: GO:0008056 +name: ocellus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects." [http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540] +is_a: GO:0007423 ! sensory organ development +relationship: part_of GO:0035214 ! eye-antennal disc development + +[Term] +id: GO:0008057 +name: eye pigment granule organization +namespace: biological_process +alt_id: GO:0008059 +alt_id: GO:0045318 +alt_id: GO:0048751 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye." [PMID:9303295] +synonym: "eye pigment granule organisation" EXACT [GOC:mah] +synonym: "eye pigment granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0048753 ! pigment granule organization + +[Term] +id: GO:0008058 +name: ocellus pigment granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm] +synonym: "ocellus pigment granule organisation" EXACT [] +synonym: "ocellus pigment granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0048753 ! pigment granule organization + +[Term] +id: GO:0008061 +name: chitin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732] +subset: goslim_drosophila +is_a: GO:0008144 ! drug binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0008062 +name: eclosion rhythm +namespace: biological_process +def: "The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn." [PMID:11715043] +is_a: GO:0048512 ! circadian behavior +relationship: part_of GO:0007562 ! eclosion + +[Term] +id: GO:0008063 +name: Toll signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:11135568, PMID:19126860] +synonym: "Tl signaling pathway" EXACT [] +synonym: "Tl signalling pathway" EXACT [] +synonym: "Toll signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway + +[Term] +id: GO:0008064 +name: regulation of actin polymerization or depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah] +is_a: GO:0030832 ! regulation of actin filament length +is_a: GO:0110053 ! regulation of actin filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008154 ! actin polymerization or depolymerization +relationship: regulates GO:0008154 ! actin polymerization or depolymerization + +[Term] +id: GO:0008065 +name: establishment of blood-nerve barrier +namespace: biological_process +def: "The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier." [GOC:dgh] +synonym: "establishment of blood/nerve barrier" EXACT [] +is_a: GO:0001885 ! endothelial cell development +relationship: part_of GO:0007422 ! peripheral nervous system development + +[Term] +id: GO:0008066 +name: glutamate receptor activity +namespace: molecular_function +def: "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0016595 ! glutamate binding + +[Term] +id: GO:0008067 +name: obsolete metabotropic glutamate, GABA-B-like receptor activity +namespace: molecular_function +alt_id: GO:0001643 +alt_id: GO:0001645 +def: "OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor." [GOC:dph, GOC:mah, GOC:tb, IUPHAR_GPCR:1285] +comment: This term was made obsolete because it represents a gene product and is named based on protein features. +synonym: "class C G protein coupled receptor" BROAD [] +synonym: "class C G-protein coupled receptor" BROAD [] +synonym: "class C GPCR" BROAD [] +synonym: "class C orphan receptor activity" EXACT [] +synonym: "metabotropic glutamate, GABA-B-like receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0008068 +name: extracellularly glutamate-gated chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane." [GOC:mtg_transport, ISBN:0815340729] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'. +synonym: "extracellular-glutamate-gated chloride channel activity" EXACT [] +is_a: GO:0005234 ! extracellularly glutamate-gated ion channel activity +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity + +[Term] +id: GO:0008069 +name: dorsal/ventral axis specification, ovarian follicular epithelium +namespace: biological_process +def: "Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:dph, GOC:mtg_sensu, GOC:tb] +synonym: "dorsal-ventral axis specification, ovarian follicular epithelium" EXACT [GOC:mah] +synonym: "dorsal/ventral axis determination, follicular epithelium" RELATED [] +synonym: "dorsal/ventral axis determination, ovarian follicular epithelium" EXACT [GOC:dph, GOC:tb] +synonym: "dorsoventral axis specification, ovarian follicular epithelium" EXACT [GOC:mah] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009950 ! dorsal/ventral axis specification +is_a: GO:0016334 ! establishment or maintenance of polarity of follicular epithelium +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0008070 +name: maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded +namespace: biological_process +def: "Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "maternal determination of dorsal-ventral axis, ovarian follicular epithelium, germ-line encoded" EXACT [GOC:mah] +synonym: "maternal determination of dorsoventral axis, ovarian follicular epithelium, germ-line encoded" EXACT [GOC:mah] +is_a: GO:0008069 ! dorsal/ventral axis specification, ovarian follicular epithelium + +[Term] +id: GO:0008071 +name: maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded +namespace: biological_process +def: "Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "maternal determination of dorsal-ventral axis, ovarian follicular epithelium, soma encoded" EXACT [GOC:mah] +synonym: "maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded" BROAD [] +synonym: "maternal determination of dorsoventral axis, ovarian follicular epithelium, soma encoded" EXACT [GOC:mah] +is_a: GO:0008069 ! dorsal/ventral axis specification, ovarian follicular epithelium + +[Term] +id: GO:0008073 +name: ornithine decarboxylase inhibitor activity +namespace: molecular_function +def: "The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase." [GOC:jl] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0042979 ! ornithine decarboxylase regulator activity +relationship: negatively_regulates GO:0004586 ! ornithine decarboxylase activity + +[Term] +id: GO:0008074 +name: guanylate cyclase complex, soluble +namespace: cellular_component +def: "Complex that possesses guanylate cyclase activity and is not bound to a membrane." [GOC:mah] +comment: See also the molecular function term 'guanylate cyclase activity ; GO:0004383'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0008075 +name: obsolete receptor guanylate cyclase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate." [EC:4.6.1.2] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "receptor guanylate cyclase activity" EXACT [] +is_obsolete: true +consider: GO:0004383 +consider: GO:0038023 + +[Term] +id: GO:0008076 +name: voltage-gated potassium channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential." [GOC:mah] +synonym: "voltage gated potassium channel complex" EXACT [] +synonym: "voltage-dependent potassium channel complex" EXACT [] +synonym: "voltage-sensitive potassium channel complex" EXACT [] +xref: NIF_Subcellular:sao371494298 +is_a: GO:0034705 ! potassium channel complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0008077 +name: obsolete Hsp70/Hsp90 organizing protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:rb] +comment: This term was made obsolete because it represents a specific gene product rather than a molecular function. +synonym: "Hsp70/Hsp90 organising protein activity" EXACT [] +synonym: "Hsp70/Hsp90 organizing protein activity" EXACT [] +is_obsolete: true +consider: GO:0030674 + +[Term] +id: GO:0008078 +name: mesodermal cell migration +namespace: biological_process +def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047] +synonym: "mesoderm cell migration" EXACT [] +is_a: GO:0001667 ! ameboidal-type cell migration + +[Term] +id: GO:0008079 +name: translation termination factor activity +namespace: molecular_function +def: "Functions in the termination of translation." [GOC:ma] +is_a: GO:0008135 ! translation factor activity, RNA binding +relationship: part_of GO:0006415 ! translational termination + +[Term] +id: GO:0008080 +name: N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] +xref: EC:2.3.1.5 +xref: Reactome:R-HSA-2468039 "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2" +xref: Reactome:R-HSA-2473152 "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2" +xref: Reactome:R-HSA-6790987 "NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842" +is_a: GO:0016407 ! acetyltransferase activity +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0008081 +name: phosphoric diester hydrolase activity +namespace: molecular_function +alt_id: GO:0004434 +alt_id: GO:0016792 +def: "Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group." [EC:3.1.4, GOC:curators] +subset: goslim_chembl +synonym: "phosphodiesterase" NARROW [] +xref: EC:3.1.4 +xref: Reactome:R-HSA-5693578 "TDP1 and TDP2 process unligatable DSB ends" +is_a: GO:0042578 ! phosphoric ester hydrolase activity + +[Term] +id: GO:0008083 +name: growth factor activity +namespace: molecular_function +def: "The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation." [ISBN:0815316194] +comment: Also consider annotating to 'receptor agonist activity ; GO:0048018'. +subset: goslim_chembl +is_a: GO:0048018 ! receptor ligand activity + +[Term] +id: GO:0008084 +name: imaginal disc growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an imaginal disc growth factor receptor." [GOC:mah] +synonym: "imaginal disc growth factor" NARROW [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0008085 +name: obsolete phototransduction, visible light, light adaptation +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because the term name is ambiguous. +synonym: "phototransduction, visible light, light adaptation" EXACT [] +is_obsolete: true +consider: GO:0007602 + +[Term] +id: GO:0008086 +name: light-activated voltage-gated calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport] +synonym: "light-activated voltage gated calcium channel activity" EXACT [] +synonym: "light-activated voltage-dependent calcium channel activity" EXACT [] +is_a: GO:0005245 ! voltage-gated calcium channel activity +is_a: GO:0010461 ! light-activated ion channel activity +relationship: part_of GO:0019722 ! calcium-mediated signaling + +[Term] +id: GO:0008087 +name: light-activated voltage-gated calcium channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus." [GOC:mah, PMID:9223679] +synonym: "light-activated voltage gated calcium channel complex" EXACT [] +synonym: "light-activated voltage-dependent calcium channel complex" EXACT [] +synonym: "light-activated voltage-sensitive calcium channel complex" EXACT [] +is_a: GO:0005891 ! voltage-gated calcium channel complex + +[Term] +id: GO:0008088 +name: axo-dendritic transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194] +subset: goslim_synapse +synonym: "axon cargo transport" NARROW [] +synonym: "axonal transport" NARROW [] +synonym: "axoplasmic transport" NARROW [] +xref: Wikipedia:Axoplasmic_transport +is_a: GO:0010970 ! transport along microtubule +relationship: occurs_in GO:0043005 ! neuron projection + +[Term] +id: GO:0008089 +name: anterograde axonal transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." [ISBN:0815316194] +subset: goslim_synapse +synonym: "anterograde axon cargo transport" EXACT [] +is_a: GO:0098930 ! axonal transport +relationship: occurs_in GO:1904115 ! axon cytoplasm + +[Term] +id: GO:0008090 +name: retrograde axonal transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] +subset: goslim_synapse +synonym: "retrograde axon cargo transport" EXACT [] +is_a: GO:0098930 ! axonal transport +relationship: occurs_in GO:1904115 ! axon cytoplasm + +[Term] +id: GO:0008091 +name: spectrin +namespace: cellular_component +def: "Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins." [GOC:curators, ISBN:0815316194] +xref: NIF_Subcellular:sao536287099 +xref: Wikipedia:Spectrin +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030864 ! cortical actin cytoskeleton + +[Term] +id: GO:0008092 +name: cytoskeletal protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)." [GOC:mah] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_yeast +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0008093 +name: cytoskeletal anchor activity +namespace: molecular_function +def: "The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07, PMID:30323238] +synonym: "cytoskeletal adaptor activity" EXACT [] +is_a: GO:0008092 ! cytoskeletal protein binding +is_a: GO:0030674 ! protein-macromolecule adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17668 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19119 xsd:anyURI + +[Term] +id: GO:0008094 +name: DNA-dependent ATPase activity +namespace: molecular_function +alt_id: GO:0004011 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction." [GOC:jl] +synonym: "adenosinetriphosphatase (DNA-dependent)" EXACT [] +synonym: "DNA dependent ATPase activity" EXACT [] +synonym: "DNA-dependent adenosinetriphosphatase activity" EXACT [] +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0008096 +name: juvenile hormone epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol." [GOC:mah, PMID:8396141] +xref: EC:3.3.2 +is_a: GO:0004301 ! epoxide hydrolase activity + +[Term] +id: GO:0008097 +name: 5S rRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome." [GOC:jl, ISBN:0321000382] +is_a: GO:0019843 ! rRNA binding + +[Term] +id: GO:0008098 +name: 5S rRNA primary transcript binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the unprocessed 5S ribosomal RNA transcript." [GOC:jl] +is_a: GO:0008097 ! 5S rRNA binding + +[Term] +id: GO:0008100 +name: obsolete lipophorin +namespace: molecular_function +def: "OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects." [ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "lipophorin" EXACT [] +is_obsolete: true +replaced_by: GO:0005319 + +[Term] +id: GO:0008103 +name: oocyte microtubule cytoskeleton polarization +namespace: biological_process +alt_id: GO:0048129 +def: "Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11807042] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007309 ! oocyte axis specification +relationship: part_of GO:0016325 ! oocyte microtubule cytoskeleton organization + +[Term] +id: GO:0008104 +name: protein localization +namespace: biological_process +alt_id: GO:0008105 +def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] +synonym: "asymmetric protein localisation" RELATED [GOC:mah] +synonym: "asymmetric protein localization" RELATED [] +synonym: "establishment and maintenance of asymmetric protein localization" RELATED [] +synonym: "establishment and maintenance of protein localization" RELATED [] +synonym: "protein localisation" EXACT [GOC:mah] +is_a: GO:0033036 ! macromolecule localization + +[Term] +id: GO:0008106 +name: alcohol dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+." [EC:1.1.1.2] +synonym: "alcohol:NADP dehydrogenase activity" EXACT [] +synonym: "aldehyde reductase (NADPH) activity" EXACT [EC:1.1.1.2] +synonym: "aldehyde reductase (NADPH2) activity" EXACT [] +synonym: "NADP-aldehyde reductase activity" EXACT [] +xref: EC:1.1.1.2 +xref: MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN +is_a: GO:0004033 ! aldo-keto reductase (NADP) activity + +[Term] +id: GO:0008107 +name: galactoside 2-alpha-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R." [EC:2.4.1.69, RHEA:50667] +synonym: "alpha(1,2)-L-fucosyltransferase activity" EXACT [] +synonym: "alpha-(1->2)-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "alpha-2-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "alpha-2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "beta-galactoside alpha-1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "blood group H alpha-2-fucosyltransferase activity" NARROW [EC:2.4.1.69] +synonym: "blood-group substance H-dependent fucosyltransferase activity" NARROW [EC:2.4.1.69] +synonym: "galactoside 2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "GDP fucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "GDP-L-fucose:lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphospho-L-fucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "guanosine diphosphofucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity" NARROW [EC:2.4.1.69] +synonym: "H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] +synonym: "secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity" NARROW [EC:2.4.1.69] +synonym: "secretor-type beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] +xref: EC:2.4.1.69 +xref: MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-9036987 "FUT2 transfers Fuc to Type 1 chains to form H antigen-sec" +xref: Reactome:R-HSA-9603982 "FUT2 transfers Fuc to LeA to form LeB" +xref: Reactome:R-HSA-9603983 "FUT2 transfers Fuc to LeX to form LeY" +xref: RHEA:50667 +is_a: GO:0031127 ! alpha-(1,2)-fucosyltransferase activity + +[Term] +id: GO:0008108 +name: UDP-glucose:hexose-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose." [EC:2.7.7.12, RHEA:13989] +synonym: "Gal-1-P uridylyltransferase activity" BROAD [EC:2.7.7.12] +synonym: "galactose-1-phosphate uridylyltransferase activity" BROAD [EC:2.7.7.12] +synonym: "hexose 1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "UDP-glucose-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "UDPglucose-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] +synonym: "uridyl transferase activity" BROAD [EC:2.7.7.12] +synonym: "uridyltransferase activity" BROAD [EC:2.7.7.12] +synonym: "uridylyl removing enzyme activity" BROAD [EC:2.7.7.12] +xref: EC:2.7.7.12 +xref: KEGG_REACTION:R00955 +xref: MetaCyc:GALACTURIDYLYLTRANS-RXN +xref: Reactome:R-HSA-5610038 "Defective GALT does not transfer UMP to Gal1P" +xref: Reactome:R-HSA-70361 "GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal" +xref: RHEA:13989 +is_a: GO:0070569 ! uridylyltransferase activity + +[Term] +id: GO:0008109 +name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.150] +synonym: "galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] +synonym: "N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] +synonym: "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity" EXACT [EC:2.4.1.150] +synonym: "UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.150] +synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase" BROAD [EC:2.4.1.150] +xref: EC:2.4.1.150 +xref: MetaCyc:2.4.1.150-RXN +xref: RHEA:17413 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0008110 +name: L-histidine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate." [EC:2.6.1.38, RHEA:16565] +synonym: "histidine aminotransferase activity" BROAD [] +synonym: "histidine transaminase activity" BROAD [EC:2.6.1.38] +synonym: "histidine-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.38] +xref: EC:2.6.1.38 +xref: KEGG_REACTION:R01161 +xref: MetaCyc:HISTTRANSAM-RXN +xref: RHEA:16565 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0008111 +name: alpha-methylacyl-CoA racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA." [EC:5.1.99.4] +synonym: "2-methylacyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.4] +xref: EC:5.1.99.4 +xref: MetaCyc:5.1.99.4-RXN +xref: Reactome:R-HSA-192056 "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA" +xref: Reactome:R-HSA-193452 "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA" +xref: Reactome:R-HSA-193736 "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA" +xref: Reactome:R-HSA-193763 "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA" +xref: Reactome:R-HSA-389897 "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA" +xref: RHEA:12657 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0008112 +name: nicotinamide N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine." [EC:2.1.1.1, RHEA:23884] +synonym: "nicotinamide methyltransferase activity" EXACT [EC:2.1.1.1] +synonym: "S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity" EXACT [EC:2.1.1.1] +xref: EC:2.1.1.1 +xref: KEGG_REACTION:R01269 +xref: MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-5359451 "NNMT transfers CH3 from SAM to NAM to form MNA" +xref: RHEA:23884 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0008113 +name: peptide-methionine (S)-S-oxide reductase activity +namespace: molecular_function +alt_id: GO:0033742 +alt_id: GO:0072561 +def: "Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.8.4.11, GOC:mah, GOC:vw, PMID:11169920] +synonym: "methionine S-oxide reductase (S-form oxidizing) activity" EXACT [EC:1.8.4.11] +synonym: "methionine S-oxide reductase activity" BROAD [EC:1.8.4.11] +synonym: "methionine sulfoxide (protein) reductase activity" EXACT [] +synonym: "methionine sulfoxide reductase A activity" EXACT [EC:1.8.4.11] +synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.11] +synonym: "methionine sulphoxide reductase A activity" EXACT [EC:1.8.4.11] +synonym: "MsrA" RELATED [EC:1.8.4.11] +synonym: "peptide Met(O) reductase activity" EXACT [EC:1.8.4.11] +synonym: "peptide methionine sulfoxide reductase activity" EXACT [EC:1.8.4.11] +synonym: "peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity" EXACT [EC:1.8.4.11] +synonym: "peptide-methionine-(S)-S-oxide reductase activity" EXACT [] +synonym: "protein-methionine-S-oxide reductase activity" EXACT [] +xref: EC:1.8.4.11 +xref: MetaCyc:RXN-8668 +xref: MetaCyc:RXN-8669 +xref: Reactome:R-HSA-1222363 "MsrA/B reduces peptide-methionine S/R-sulfoxides" +xref: Reactome:R-HSA-5676940 "MSRA reduces L-methyl-(S)-S-oxide to L-Methionine" +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0008114 +name: phosphogluconate 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH." [EC:1.1.1.43] +synonym: "2-keto-6-phosphogluconate reductase activity" EXACT [EC:1.1.1.43] +synonym: "6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.43] +synonym: "6-phosphogluconate 2-dehydrogenase activity" EXACT [] +synonym: "6-phosphogluconate dehydrogenase (NAD)" EXACT [EC:1.1.1.43] +synonym: "6-phosphogluconic dehydrogenase activity" BROAD [EC:1.1.1.43] +synonym: "gluconate 6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.43] +synonym: "phosphogluconate dehydrogenase activity" EXACT [EC:1.1.1.43] +xref: EC:1.1.1.43 +xref: MetaCyc:1.1.1.43-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008115 +name: sarcosine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2)." [EC:1.5.3.1, RHEA:13313] +synonym: "sarcosine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.1] +xref: EC:1.5.3.1 +xref: KEGG_REACTION:R00610 +xref: MetaCyc:SARCOX-RXN +xref: RHEA:13313 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0008116 +name: prostaglandin-I synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2)." [EC:5.3.99.4, RHEA:23580] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity" EXACT [EC:5.3.99.4] +synonym: "cytochrome P450 CYP8A1" NARROW [] +synonym: "PGI(2) synthase activity" EXACT [EC:5.3.99.4] +synonym: "PGI(2) synthetase activity" EXACT [EC:5.3.99.4] +synonym: "PGI2 synthase activity" EXACT [EC:5.3.99.4] +synonym: "PGI2 synthetase activity" EXACT [EC:5.3.99.4] +synonym: "prostacyclin synthase activity" EXACT [EC:5.3.99.4] +synonym: "prostacycline synthetase activity" EXACT [EC:5.3.99.4] +synonym: "prostagladin I2 synthetase activity" EXACT [EC:5.3.99.4] +xref: EC:5.3.99.4 +xref: KEGG_REACTION:R02267 +xref: MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN +xref: Reactome:R-HSA-76496 "PTGIS, CYP8A1 isomerise PGH2 to PGI2" +xref: RHEA:23580 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0008117 +name: sphinganine-1-phosphate aldolase activity +namespace: molecular_function +alt_id: GO:0016001 +def: "Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde." [EC:4.1.2.27] +synonym: "dihydrosphingosine 1-phosphate aldolase activity" EXACT [EC:4.1.2.27] +synonym: "sphinganine-1-phosphate alkanal-lyase activity" EXACT [EC:4.1.2.27] +synonym: "sphinganine-1-phosphate lyase activity" EXACT [EC:4.1.2.27] +synonym: "sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)" EXACT [EC:4.1.2.27] +synonym: "sphinganine-1-phosphate palmitaldehyde-lyase activity" EXACT [EC:4.1.2.27] +synonym: "sphingosine-1-phosphate aldolase activity" EXACT [EC:4.1.2.27] +synonym: "sphingosine-1-phosphate lyase activity" EXACT [EC:4.1.2.27] +xref: EC:4.1.2.27 +xref: MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN +xref: Reactome:R-HSA-428676 "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal" +xref: Reactome:R-HSA-428681 "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal" +xref: RHEA:18593 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008118 +name: N-acetyllactosaminide alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein." [EC:2.4.99.6, RHEA:52316] +synonym: "alpha2->3 sialyltransferase activity" EXACT [EC:2.4.99.6] +synonym: "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.6] +synonym: "cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity" EXACT [EC:2.4.99.6] +synonym: "SiaT" RELATED [EC:2.4.99.6] +xref: EC:2.4.99.6 +xref: MetaCyc:2.4.99.6-RXN +xref: RHEA:52316 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0008119 +name: thiopurine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether." [EC:2.1.1.67] +synonym: "6-thiopurine transmethylase activity" EXACT [EC:2.1.1.67] +synonym: "mercaptopurine methyltransferase activity" EXACT [EC:2.1.1.67] +synonym: "S-adenosyl-L-methionine:thiopurine S-methyltransferase activity" EXACT [EC:2.1.1.67] +synonym: "thiopurine methyltransferase activity" EXACT [EC:2.1.1.67] +synonym: "TPMT" RELATED [EC:2.1.1.67] +xref: EC:2.1.1.67 +xref: MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-158609 "TPMT transfers CH3 from AdoMet to 6MP" +xref: Reactome:R-HSA-5603379 "TPMT does not transfer CH3 from AdoMet to 6MP" +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0008120 +name: ceramide glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine." [EC:2.4.1.80] +synonym: "ceramide:UDP-glucose glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "ceramide:UDPGlc glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "glucosylceramide synthase activity" EXACT [EC:2.4.1.80] +synonym: "UDP-glucose-ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "UDP-glucose:ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "UDP-glucose:N-acylsphingosine D-glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "UDPglucose:N-acylsphingosine D-glucosyltransferase activity" EXACT [EC:2.4.1.80] +synonym: "uridine diphosphoglucose-ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] +xref: EC:2.4.1.80 +xref: MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-1638104 "Ceramide glucosyltransferase (UGCG) catalyses the transfer of glucose to ceramide" +xref: RHEA:12088 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0008121 +name: ubiquinol-cytochrome-c reductase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+." [EC:1.10.2.2, ISBN:0198547684] +synonym: "coenzyme Q-cytochrome c oxidoreductase activity" EXACT [] +synonym: "coenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] +synonym: "coenzyme QH2-cytochrome c reductase activity" EXACT [EC:1.10.2.2] +synonym: "complex III (mitochondrial electron transport) activity" NARROW [EC:1.10.2.2] +synonym: "CoQH2-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "cytochrome bc1 activity" EXACT [] +synonym: "cytochrome bc1 complex" RELATED [] +synonym: "dihydrocoenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] +synonym: "mitochondrial electron transport complex III" RELATED [EC:1.10.2.2] +synonym: "QH2:cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "reduced coenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] +synonym: "reduced ubiquinone-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "reduced ubiquinone-cytochrome c reductase, complex III (mitochondrial electron transport)" RELATED [EC:1.10.2.2] +synonym: "ubihydroquinol:cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinol-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinol-cytochrome c-2 oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinol-cytochrome c1 oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinol-cytochrome c2 reductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinol:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinone--cytochrome-c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinone-cytochrome b-c1 oxidoreductase activity" EXACT [] +synonym: "ubiquinone-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] +synonym: "ubiquinone-cytochrome c reductase activity" EXACT [EC:1.10.2.2] +xref: EC:1.10.2.2 +xref: MetaCyc:1.10.2.2-RXN +is_a: GO:0009055 ! electron transfer activity +is_a: GO:0016681 ! oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor + +[Term] +id: GO:0008123 +name: cholesterol 7-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O." [EC:1.14.14.23] +synonym: "cholesterol 7-alpha-hydroxylase activity" EXACT [] +synonym: "cholesterol 7alpha-hydroxylase activity" EXACT [EC:1.14.14.23] +synonym: "cholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.14.23] +synonym: "cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.14.23] +synonym: "cytochrome P450 CYP7A1" NARROW [] +xref: EC:1.14.14.23 +xref: MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-192051 "CYP7A1 7-hydroxylates CHOL" +xref: RHEA:21812 +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0008124 +name: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O." [EC:4.2.1.96, RHEA:11920] +synonym: "(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]" RELATED [EC:4.2.1.96] +synonym: "4-alpha-hydroxy-tetrahydropterin dehydratase activity" EXACT [EC:4.2.1.96] +synonym: "4a-hydroxytetrahydrobiopterin dehydratase activity" EXACT [] +synonym: "4a-hydroxytetrahydrobiopterin hydro-lyase activity" EXACT [EC:4.2.1.96] +synonym: "4alpha-hydroxy-tetrahydropterin dehydratase activity" EXACT [EC:4.2.1.96] +synonym: "pterin-4-alpha-carbinolamine dehydratase activity" EXACT [] +synonym: "pterin-4a-carbinolamine dehydratase activity" EXACT [] +synonym: "pterin-4alpha-carbinolamine dehydratase activity" RELATED [] +synonym: "tetrahydrobiopterin dehydratase activity" EXACT [EC:4.2.1.96] +xref: EC:4.2.1.96 +xref: KEGG_REACTION:R04734 +xref: MetaCyc:RXN-7908 +xref: Reactome:R-HSA-71146 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O" +xref: RHEA:11920 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008125 +name: obsolete pancreatic elastase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa." [EC:3.4.21.36] +comment: This term was made obsolete because it represents a gene product. +synonym: "elaszym" RELATED [EC:3.4.21.36] +synonym: "pancreatic elastase I activity" EXACT [] +synonym: "pancreatopeptidase E activity" EXACT [EC:3.4.21.36] +synonym: "serine elastase" BROAD [EC:3.4.21.36] +xref: EC:3.4.21.36 +xref: MetaCyc:3.4.21.36-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008126 +name: acetylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate." [EC:3.1.1.6] +synonym: "acetic ester hydrolase activity" EXACT [EC:3.1.1.6] +synonym: "acetic-ester acetylhydrolase activity" EXACT [EC:3.1.1.6] +synonym: "C-esterase (in animal tissues)" NARROW [EC:3.1.1.6] +synonym: "chloroesterase" NARROW [EC:3.1.1.6] +synonym: "citrus acetylesterase" NARROW [EC:3.1.1.6] +synonym: "p-nitrophenyl acetate esterase" NARROW [EC:3.1.1.6] +xref: EC:3.1.1.6 +xref: MetaCyc:ACETYLESTERASE-RXN +xref: UM-BBD_reactionID:r0170 +is_a: GO:0034338 ! short-chain carboxylesterase activity + +[Term] +id: GO:0008127 +name: quercetin 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO." [EC:1.13.11.24, RHEA:15381] +synonym: "flavonol 2,4-oxygenase activity" EXACT [EC:1.13.11.24] +synonym: "quercetin:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.24] +synonym: "quercetinase activity" EXACT [EC:1.13.11.24] +xref: EC:1.13.11.24 +xref: KEGG_REACTION:R02156 +xref: MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN +xref: Reactome:R-HSA-8953398 "PIR oxygenates quercetin" +xref: RHEA:15381 +xref: UM-BBD_reactionID:r0891 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0008129 +name: obsolete actinidain activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'." [EC:3.4.22.14] +comment: This term was made obsolete because it represents a gene product. +synonym: "actinidain activity" EXACT [] +synonym: "actinidia anionic protease activity" NARROW [EC:3.4.22.14] +synonym: "actinidin activity" EXACT [EC:3.4.22.14] +synonym: "proteinase A2 of actinidia chinensis" RELATED [EC:3.4.22.14] +xref: EC:3.4.22.14 +xref: MetaCyc:3.4.22.14-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0008130 +name: obsolete neutrophil collagenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I." [EC:3.4.24.34] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrix metalloproteinase 8 activity" EXACT [EC:3.4.24.34] +synonym: "MMP-8" EXACT [] +synonym: "neutrophil collagenase activity" EXACT [] +synonym: "PMNL collagenase activity" EXACT [EC:3.4.24.34] +xref: EC:3.4.24.34 +xref: MetaCyc:3.4.24.34-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008131 +name: primary amine oxidase activity +namespace: molecular_function +alt_id: GO:0004041 +alt_id: GO:0008122 +def: "Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide." [EC:1.4.3.21, EC:1.4.3.22, EC:1.4.3.4, MetaCyc:RXN-9597] +synonym: "amine oxidase (copper-containing) activity" NARROW [] +synonym: "amine oxidase activity" BROAD [EC:1.4.3.21] +synonym: "primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.21] +xref: EC:1.4.3.21 +xref: KEGG_REACTION:R01853 +xref: MetaCyc:RXN-9597 +xref: Reactome:R-HSA-141186 "MAOA:FAD oxidatively deaminates of 5HT" +xref: Reactome:R-HSA-141200 "MAOB:FAD oxidatively deaminates of PEA" +xref: Reactome:R-HSA-141202 "MAOB:FAD oxidatively deaminates TYR" +xref: Reactome:R-HSA-374909 "Metabolism of Noradrenaline" +xref: Reactome:R-HSA-379382 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC)" +xref: Reactome:R-HSA-379395 "Oxidation of 3-Methoxytyramine to homovanillic acid" +xref: Reactome:R-HSA-5603108 "Defective MAOA does not oxidatively deaminate 5HT" +xref: Reactome:R-HSA-5696146 "AOC2 deaminates TYR" +xref: Reactome:R-HSA-5696183 "AOC3 deaminates BZAM" +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0008132 +name: obsolete pancreatic elastase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin." [EC:3.4.21.36, EC:3.4.21.71] +comment: This term was made obsolete because it represents a gene product. +synonym: "pancreatic elastase activity" EXACT [] +xref: EC:3.4.21 +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008133 +name: obsolete collagenase activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "collagenase activity" EXACT [] +xref: EC:3.4.24 +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008134 +name: transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription." [ISBN:0198506732] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_yeast +synonym: "TF binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0008135 +name: translation factor activity, RNA binding +namespace: molecular_function +def: "Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome." [GOC:ai, GOC:vw] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +subset: goslim_yeast +synonym: "translation factor activity, nucleic acid binding" BROAD [GOC:mah] +is_a: GO:0003723 ! RNA binding +is_a: GO:0090079 ! translation regulator activity, nucleic acid binding +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0008137 +name: NADH dehydrogenase (ubiquinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out)." [EC:7.1.1.2] +synonym: "coenzyme Q reductase activity" EXACT [EC:7.1.1.2] +synonym: "complex 1 dehydrogenase activity" RELATED [EC:7.1.1.2] +synonym: "complex I (electron transport chain) activity" RELATED [EC:7.1.1.2] +synonym: "complex I (mitochondrial electron transport) activity" RELATED [EC:7.1.1.2] +synonym: "complex I (NADH:Q1 oxidoreductase) activity" RELATED [EC:7.1.1.2] +synonym: "dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity" EXACT [EC:7.1.1.2] +synonym: "DPNH-coenzyme Q reductase activity" EXACT [EC:7.1.1.2] +synonym: "DPNH-ubiquinone reductase activity" EXACT [EC:7.1.1.2] +synonym: "electron transfer complex I activity" RELATED [EC:7.1.1.2] +synonym: "mitochondrial electron transport complex 1 activity" NARROW [EC:7.1.1.2] +synonym: "mitochondrial electron transport complex I activity" NARROW [EC:7.1.1.2] +synonym: "NADH coenzyme Q1 reductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-coenzyme Q oxidoreductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-coenzyme Q reductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-CoQ oxidoreductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-CoQ reductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-Q6 oxidoreductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-ubiquinone oxidoreductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-ubiquinone reductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH-ubiquinone-1 reductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH:ubiquinone oxidoreductase activity" EXACT [EC:7.1.1.2] +synonym: "NADH:ubiquinone oxidoreductase complex activity" RELATED [EC:7.1.1.2] +synonym: "reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity" EXACT [EC:7.1.1.2] +synonym: "type 1 dehydrogenase activity" RELATED [EC:7.1.1.2] +synonym: "ubiquinone reductase activity" EXACT [] +xref: EC:7.1.1.2 +xref: MetaCyc:NADH-DEHYDROG-A-RXN +xref: MetaCyc:RXN0-5330 +xref: Reactome:R-HSA-163217 "Complex I oxidises NADH to NAD+, reduces CoQ to QH2" +xref: RHEA:29091 +is_a: GO:0050136 ! NADH dehydrogenase (quinone) activity + +[Term] +id: GO:0008138 +name: protein tyrosine/serine/threonine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [GOC:mah] +comment: Note that this term applies only to free amino acids. Consider 'protein serine/threonine phosphatase activity' or 'protein tyrosine/serine/threonine phosphatase activity' if you want to annotate a protein phosphatase. +synonym: "dual-specificity protein phosphatase" BROAD [] +xref: Reactome:R-HSA-5675373 "Nuclear DUSPs dephosphorylate MAPKs" +xref: Reactome:R-HSA-5675376 "Cytosolic DUSPs dephosphorylate MAPKs" +is_a: GO:0004721 ! phosphoprotein phosphatase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12183 xsd:anyURI + +[Term] +id: GO:0008139 +name: nuclear localization sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus." [GOC:ai] +synonym: "NLS binding" EXACT [] +synonym: "nuclear localisation sequence binding" EXACT [GOC:mah] +synonym: "nuclear localization signal binding" EXACT [] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0008140 +name: cAMP response element binding protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB protein)." [GOC:mah] +synonym: "3',5' cAMP response element binding protein binding" EXACT [] +synonym: "3',5'-cAMP response element binding protein binding" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate response element binding protein binding" EXACT [] +synonym: "CBP" RELATED [GOC:bf] +synonym: "CREB binding" EXACT [] +synonym: "cyclic AMP response element binding protein binding" EXACT [] +is_a: GO:0140297 ! DNA-binding transcription factor binding + +[Term] +id: GO:0008141 +name: obsolete puparial glue (sensu Diptera) +namespace: molecular_function +def: "OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147)." [PMID:825230] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "puparial glue (sensu Diptera)" EXACT [] +is_obsolete: true +consider: GO:0005198 +consider: GO:0007594 + +[Term] +id: GO:0008142 +name: oxysterol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol." [GOC:curators] +is_a: GO:0032934 ! sterol binding + +[Term] +id: GO:0008143 +name: poly(A) binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA." [GOC:jl] +synonym: "poly(A) binding, within an RNA molecule" EXACT [] +synonym: "poly(rA) binding" EXACT [GOC:mah] +synonym: "poly-A binding" EXACT [GOC:mah] +synonym: "polyadenylate binding" EXACT [GOC:mah] +is_a: GO:0070717 ! poly-purine tract binding + +[Term] +id: GO:0008144 +name: drug binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease." [GOC:jl, ISBN:0198506732] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0008145 +name: phenylalkylamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives." [GOC:jl] +is_a: GO:0008144 ! drug binding +is_a: GO:0043176 ! amine binding + +[Term] +id: GO:0008146 +name: sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate." [EC:2.8.2, GOC:curators] +subset: goslim_chembl +synonym: "sulphotransferase activity" EXACT [] +xref: EC:2.8.2 +xref: Reactome:R-HSA-176588 "lithocholate + PAPS => lithocholate sulfate + PAP" +xref: Reactome:R-HSA-176604 "taurolithocholate + PAPS => taurolithocholate sulfate + PAP" +xref: Reactome:R-HSA-176669 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP" +xref: Reactome:R-HSA-2022061 "Dermatan sulfate can be further sulfated on position 2 of iduronate" +is_a: GO:0016782 ! transferase activity, transferring sulfur-containing groups + +[Term] +id: GO:0008147 +name: structural constituent of bone +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of bone." [GOC:mah] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0008148 +name: obsolete negative transcription elongation factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "negative transcription elongation factor activity" EXACT [] +is_obsolete: true +consider: GO:0032785 + +[Term] +id: GO:0008149 +name: obsolete para-aminobenzoic acid (PABA) synthase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai, MetaCyc:PABASYN-CPLX] +comment: This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered. +synonym: "para-aminobenzoic acid (PABA) synthase" EXACT [] +is_obsolete: true +consider: GO:0008696 +consider: GO:0046820 + +[Term] +id: GO:0008150 +name: biological_process +namespace: biological_process +alt_id: GO:0000004 +alt_id: GO:0007582 +alt_id: GO:0044699 +def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] +comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_pombe +subset: goslim_yeast +synonym: "biological process" EXACT [] +synonym: "physiological process" EXACT [] +synonym: "single organism process" RELATED [] +synonym: "single-organism process" RELATED [] +xref: Wikipedia:Biological_process +created_by: jl +creation_date: 2012-09-19T15:05:24Z + +[Term] +id: GO:0008152 +name: metabolic process +namespace: biological_process +alt_id: GO:0044236 +alt_id: GO:0044710 +def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] +comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. +subset: gocheck_do_not_manually_annotate +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "metabolic process resulting in cell growth" NARROW [] +synonym: "metabolism" EXACT [] +synonym: "metabolism resulting in cell growth" NARROW [] +synonym: "multicellular organism metabolic process" NARROW [] +synonym: "single-organism metabolic process" RELATED [] +xref: Wikipedia:Metabolism +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +created_by: jl +creation_date: 2012-10-17T15:46:40Z + +[Term] +id: GO:0008153 +name: para-aminobenzoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins." [ISBN:0198506732, MetaCyc:PWY-6543, PMID:11377864, PMID:11960743] +synonym: "4-aminobenzoic acid biosynthesis" EXACT [] +synonym: "4-aminobenzoic acid biosynthetic process" EXACT [] +synonym: "p-aminobenzoic acid biosynthesis" EXACT [] +synonym: "p-aminobenzoic acid biosynthetic process" EXACT [] +synonym: "PABA biosynthesis" EXACT [] +synonym: "PABA biosynthetic process" EXACT [] +synonym: "para-aminobenzoic acid anabolism" EXACT [] +synonym: "para-aminobenzoic acid biosynthesis" EXACT [] +synonym: "para-aminobenzoic acid formation" EXACT [] +synonym: "para-aminobenzoic acid synthesis" EXACT [] +synonym: "vitamin Bx biosynthesis" EXACT [] +synonym: "vitamin Bx biosynthetic process" EXACT [] +is_a: GO:0009073 ! aromatic amino acid family biosynthetic process +is_a: GO:0046482 ! para-aminobenzoic acid metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0008154 +name: actin polymerization or depolymerization +namespace: biological_process +def: "Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah] +is_a: GO:0007015 ! actin filament organization + +[Term] +id: GO:0008155 +name: obsolete larval behavior (sensu Drosophila) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term. +synonym: "larval behavior (sensu Drosophila)" EXACT [] +is_obsolete: true +replaced_by: GO:0030537 + +[Term] +id: GO:0008156 +name: negative regulation of DNA replication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication." [GOC:go_curators] +synonym: "DNA replication inhibitor" RELATED [] +synonym: "down regulation of DNA replication" EXACT [] +synonym: "down-regulation of DNA replication" EXACT [] +synonym: "downregulation of DNA replication" EXACT [] +synonym: "inhibition of DNA replication" NARROW [] +is_a: GO:0006275 ! regulation of DNA replication +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006260 ! DNA replication +relationship: negatively_regulates GO:0006260 ! DNA replication + +[Term] +id: GO:0008157 +name: protein phosphatase 1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme protein phosphatase 1." [GOC:jl] +is_a: GO:0019903 ! protein phosphatase binding + +[Term] +id: GO:0008158 +name: hedgehog receptor activity +namespace: molecular_function +def: "Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity." [GOC:bf, GOC:go_curators, PMID:9278137] +synonym: "patched activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0097108 ! hedgehog family protein binding + +[Term] +id: GO:0008159 +name: obsolete positive transcription elongation factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "positive transcription elongation factor activity" EXACT [] +is_obsolete: true +consider: GO:0032786 + +[Term] +id: GO:0008160 +name: protein tyrosine phosphatase activator activity +namespace: molecular_function +def: "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein." [GOC:ai, ISBN:0198506732] +is_a: GO:0072542 ! protein phosphatase activator activity +relationship: positively_regulates GO:0004725 ! protein tyrosine phosphatase activity + +[Term] +id: GO:0008161 +name: obsolete carbamate resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "carbamate resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046681 + +[Term] +id: GO:0008162 +name: obsolete cyclodiene resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "cyclodiene resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046682 + +[Term] +id: GO:0008163 +name: obsolete DDT resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "DDT resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046680 + +[Term] +id: GO:0008164 +name: obsolete organophosphorus resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "organophosphorus resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046683 + +[Term] +id: GO:0008165 +name: obsolete pyrethroid resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "pyrethroid resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046684 + +[Term] +id: GO:0008166 +name: obsolete viral replication +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it covers multiple processes and is now covered by more specific terms. +synonym: "viral replication" EXACT [] +is_obsolete: true +consider: GO:0019079 + +[Term] +id: GO:0008167 +name: obsolete sigma virus replication +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +synonym: "sigma virus replication" EXACT [] +is_obsolete: true +replaced_by: GO:0019079 + +[Term] +id: GO:0008168 +name: methyltransferase activity +namespace: molecular_function +alt_id: GO:0004480 +def: "Catalysis of the transfer of a methyl group to an acceptor molecule." [ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "methylase" BROAD [] +xref: EC:2.1.1 +xref: Reactome:R-HSA-379387 "methylation of Dopamine to form 3-Methoxytyramine" +xref: Reactome:R-HSA-379464 "Methylation of 3,4-dihydroxyphenylacetic acid to homovanillic acid" +xref: Reactome:R-HSA-6800149 "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII" +xref: Reactome:R-HSA-71286 "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine" +is_a: GO:0016741 ! transferase activity, transferring one-carbon groups + +[Term] +id: GO:0008169 +name: C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule." [GOC:ai] +xref: EC:2.1.1 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0008170 +name: N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule." [GOC:ai] +xref: EC:2.1.1 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0008171 +name: O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule." [GOC:ai] +xref: EC:2.1.1 +xref: Reactome:R-HSA-5578717 "BCDIN3D dimethylates 5' phosphate of pre-miR-145" +xref: Reactome:R-HSA-5629203 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH" +xref: Reactome:R-HSA-5629218 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1" +xref: Reactome:R-HSA-5629237 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH" +xref: Reactome:R-HSA-6790907 "Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0008172 +name: S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule." [GOC:ai] +xref: EC:2.1.1 +xref: Reactome:R-HSA-209821 "Methylation of N-acetyl-5-HT to form melatonin" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0008173 +name: RNA methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule." [GOC:mah] +comment: Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698). +xref: Reactome:R-HSA-191784 "snRNA Cap hypermethylation" +is_a: GO:0008168 ! methyltransferase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +relationship: part_of GO:0001510 ! RNA methylation + +[Term] +id: GO:0008174 +name: mRNA methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule." [GOC:mah] +is_a: GO:0008173 ! RNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +relationship: part_of GO:0080009 ! mRNA methylation + +[Term] +id: GO:0008175 +name: tRNA methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule." [GOC:mah] +xref: Reactome:R-HSA-6782879 "TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe)" +xref: Reactome:R-HSA-6782881 "LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe)" +xref: Reactome:R-HSA-6782890 "LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe)" +xref: Reactome:R-HSA-6783473 "LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe)" +xref: Reactome:R-HSA-6786500 "ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34" +xref: Reactome:R-HSA-6786567 "KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine" +is_a: GO:0008173 ! RNA methyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0030488 ! tRNA methylation + +[Term] +id: GO:0008176 +name: tRNA (guanine-N7-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine." [EC:2.1.1.33] +synonym: "7-methylguanine transfer ribonucleate methylase activity" EXACT [EC:2.1.1.33] +synonym: "N7-methylguanine methylase activity" EXACT [EC:2.1.1.33] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity" EXACT [EC:2.1.1.33] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity" EXACT [EC:2.1.1.33] +synonym: "transfer ribonucleate guanine 7-methyltransferase activity" EXACT [EC:2.1.1.33] +synonym: "tRNA guanine 7-methyltransferase activity" EXACT [EC:2.1.1.33] +xref: EC:2.1.1.33 +xref: MetaCyc:TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-6782286 "METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46" +is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity +relationship: part_of GO:0106004 ! tRNA (guanine-N7)-methylation + +[Term] +id: GO:0008177 +name: succinate dehydrogenase (ubiquinone) activity +namespace: molecular_function +alt_id: GO:0019737 +def: "Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol." [EC:1.3.5.1, RHEA:13713] +synonym: "complex II" RELATED [EC:1.3.5.1] +synonym: "fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)" RELATED [EC:1.3.5.1] +synonym: "menaquinol: fumarate oxidoreductase activity" EXACT [EC:1.3.5.1] +synonym: "quinol:fumarate oxidoreductase activity" EXACT [] +synonym: "succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)" RELATED [EC:1.3.5.1] +synonym: "succinate:ubiquinone oxidoreductase activity" EXACT [EC:1.3.5.1] +synonym: "succinic dehydrogenase activity" BROAD [EC:1.3.5.1] +xref: EC:1.3.5.1 +xref: KEGG_REACTION:R02164 +xref: MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN +xref: Reactome:R-HSA-163213 "Transfer of electrons through the succinate dehydrogenase complex" +xref: Reactome:R-HSA-70994 "Succinate <=> Fumarate (with FAD redox reaction on enzyme)" +xref: RHEA:13713 +is_a: GO:0000104 ! succinate dehydrogenase activity +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor + +[Term] +id: GO:0008179 +name: adenylate cyclase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme adenylate cyclase." [GOC:jl] +synonym: "adenylyl cyclase binding" EXACT [] +xref: Reactome:R-HSA-170672 "Galpha-olf:GTP binds to adenylate cyclase and activates it" +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0008180 +name: COP9 signalosome +namespace: cellular_component +def: "A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome." [PMID:11019806, PMID:12186635, PMID:14570571] +synonym: "COP9 complex" EXACT [GOC:krc] +synonym: "CSN" EXACT [] +synonym: "signalosome" BROAD [GOC:krc] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0008181 +name: obsolete tumor suppressor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not represent a true biological function, rather a pathology that occurs when a particular gene product is inactivated in some way. +synonym: "tumor suppressor" EXACT [] +is_obsolete: true +consider: GO:0051726 + +[Term] +id: GO:0008184 +name: glycogen phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate." [EC:2.4.1.1, MetaCyc:GLYCOPHOSPHORYL-RXN] +xref: MetaCyc:GLYCOPHOSPHORYL-RXN +xref: Reactome:R-HSA-453339 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]" +xref: Reactome:R-HSA-453358 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]" +xref: Reactome:R-HSA-71515 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]" +xref: Reactome:R-HSA-71590 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]" +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0008186 +name: RNA-dependent ATPase activity +namespace: molecular_function +alt_id: GO:0004010 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction." [GOC:jl] +synonym: "RNA-dependent adenosinetriphosphatase activity" EXACT [] +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0008187 +name: poly-pyrimidine tract binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule." [GOC:jl] +is_a: GO:0003727 ! single-stranded RNA binding + +[Term] +id: GO:0008188 +name: neuropeptide receptor activity +namespace: molecular_function +def: "Combining with a neuropeptide to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: has_part GO:0042923 ! neuropeptide binding +relationship: part_of GO:0007218 ! neuropeptide signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0008189 +name: obsolete apoptosis inhibitor activity +namespace: molecular_function +def: "OBSOLETE. The function held by products which directly block any step in the process of apoptosis." [GOC:hb] +comment: This term was made obsolete because it represents involvement in a biological process. +synonym: "apoptosis inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0043066 + +[Term] +id: GO:0008190 +name: eukaryotic initiation factor 4E binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation." [ISBN:0198506732] +synonym: "eIF4E binding" EXACT [] +is_a: GO:0031369 ! translation initiation factor binding + +[Term] +id: GO:0008191 +name: metalloendopeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity." [GOC:ai] +synonym: "metalloprotease inhibitor" NARROW [] +synonym: "metalloproteinase inhibitor" NARROW [] +is_a: GO:0004866 ! endopeptidase inhibitor activity +relationship: negatively_regulates GO:0004222 ! metalloendopeptidase activity + +[Term] +id: GO:0008192 +name: RNA guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule." [GOC:mah] +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0008193 +name: tRNA guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs." [PMID:1660461] +xref: EC:2.7.7.79 +xref: RHEA:54564 +is_a: GO:0008192 ! RNA guanylyltransferase activity +relationship: part_of GO:0099116 ! tRNA 5'-end processing + +[Term] +id: GO:0008194 +name: UDP-glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule." [InterPro:IPR004224, PMID:11846783] +xref: Reactome:R-HSA-162730 "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP" +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups + +[Term] +id: GO:0008195 +name: phosphatidate phosphatase activity +namespace: molecular_function +alt_id: GO:0004606 +def: "Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate." [EC:3.1.3.4, GOC:pr] +synonym: "3-sn-phosphatidate phosphohydrolase activity" EXACT [EC:3.1.3.4] +synonym: "acid phosphatidyl phosphatase activity" EXACT [EC:3.1.3.4] +synonym: "phosphatic acid phosphatase activity" EXACT [EC:3.1.3.4] +synonym: "phosphatic acid phosphohydrolase activity" EXACT [EC:3.1.3.4] +synonym: "phosphatidate phosphohydrolase activity" EXACT [] +synonym: "phosphatidic acid phosphatase activity" EXACT [EC:3.1.3.4] +xref: EC:3.1.3.4 +xref: MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN +xref: Reactome:R-HSA-1483203 "PA is dephosphorylated to DAG by LPIN" +xref: Reactome:R-HSA-163688 "Dephosphorylation of pChREBP (Thr 666) by PP2A" +xref: Reactome:R-HSA-163689 "Dephosphorylation of pChREBP (Ser 196) by PP2A" +xref: Reactome:R-HSA-163750 "Dephosphorylation of phosphoPFKFB1 by PP2A complex" +xref: Reactome:R-HSA-164056 "Dephosphorylation of pChREBP (Ser 568) by PP2A" +xref: Reactome:R-HSA-2029468 "Conversion of PA into DAG by PAP-1" +xref: Reactome:R-HSA-390329 "Dephosphorylation of AKT by PP2A" +xref: Reactome:R-HSA-5221130 "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol" +xref: Reactome:R-HSA-6797630 "LRPP4(LRPP1-3,5) hydrolyse LPA" +xref: Reactome:R-HSA-75899 "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate" +xref: RHEA:27429 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0008196 +name: vitellogenin receptor activity +namespace: molecular_function +def: "Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis." [GOC:bf, PMID:12429745] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0008197 +name: obsolete yolk protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "yolk protein" EXACT [] +is_obsolete: true +consider: GO:0005198 +consider: GO:0045735 + +[Term] +id: GO:0008198 +name: ferrous iron binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ferrous iron, Fe(II)." [GOC:ai] +is_a: GO:0005506 ! iron ion binding + +[Term] +id: GO:0008199 +name: ferric iron binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ferric iron, Fe(III)." [GOC:ai] +is_a: GO:0005506 ! iron ion binding + +[Term] +id: GO:0008200 +name: ion channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of an ion channel." [GOC:mah] +is_a: GO:0016248 ! channel inhibitor activity +is_a: GO:0099106 ! ion channel regulator activity + +[Term] +id: GO:0008201 +name: heparin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:jl, ISBN:0198506732] +synonym: "heparan sulfate binding" RELATED [] +is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0008202 +name: steroid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684] +synonym: "steroid metabolism" EXACT [] +xref: Wikipedia:Steroid_metabolism +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0008203 +name: cholesterol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues." [ISBN:0198506732] +synonym: "cholesterol metabolism" EXACT [] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4930 + +[Term] +id: GO:0008204 +name: ergosterol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light." [ISBN:0198506732] +synonym: "ergosterol metabolism" EXACT [] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:0016128 ! phytosteroid metabolic process +is_a: GO:0044107 ! cellular alcohol metabolic process +is_a: GO:0044255 ! cellular lipid metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0008205 +name: ecdysone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development." [ISBN:0198506732] +synonym: "ecdysone metabolism" EXACT [] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:0045455 ! ecdysteroid metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0008206 +name: bile acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators] +synonym: "bile acid metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0008207 +name: C21-steroid hormone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones." [GOC:ai] +synonym: "C21-steroid hormone metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0008208 +name: C21-steroid hormone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones." [GOC:ai] +synonym: "C21-steroid hormone breakdown" EXACT [] +synonym: "C21-steroid hormone catabolism" EXACT [] +synonym: "C21-steroid hormone degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0008207 ! C21-steroid hormone metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0008209 +name: androgen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics." [ISBN:0198506732] +synonym: "androgen metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0008210 +name: estrogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants." [ISBN:0198506732] +synonym: "estrogen metabolism" EXACT [] +synonym: "oestrogen metabolic process" EXACT [] +synonym: "oestrogen metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0008211 +name: glucocorticoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [ISBN:0198506732] +synonym: "glucocorticoid metabolism" EXACT [] +synonym: "glucocorticosteroid metabolic process" EXACT [] +synonym: "glucocorticosteroid metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0008212 +name: mineralocorticoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance." [ISBN:0198506732] +synonym: "mineralocorticoid metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0008213 +name: protein alkylation +namespace: biological_process +def: "The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom." [GOC:ma] +subset: goslim_yeast +synonym: "protein amino acid alkylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0008214 +name: protein dealkylation +namespace: biological_process +def: "The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom." [GOC:ai] +synonym: "protein amino acid dealkylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0008215 +name: spermine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication." [GOC:curators] +synonym: "spermine metabolism" EXACT [] +is_a: GO:0006595 ! polyamine metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0008216 +name: spermidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] +synonym: "spermidine metabolism" EXACT [] +is_a: GO:0006595 ! polyamine metabolic process + +[Term] +id: GO:0008217 +name: regulation of blood pressure +namespace: biological_process +def: "Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." [GOC:dph, GOC:mtg_cardio, ISBN:0721643949] +synonym: "blood pressure homeostasis" RELATED [] +synonym: "blood pressure regulation" EXACT [] +synonym: "control of blood pressure" RELATED [] +xref: Wikipedia:Blood_pressure#Regulation +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0008015 ! blood circulation + +[Term] +id: GO:0008218 +name: bioluminescence +namespace: biological_process +def: "The production of light by certain enzyme-catalyzed reactions in cells." [ISBN:0198506732] +subset: goslim_chembl +subset: goslim_metagenomics +xref: Wikipedia:Bioluminescence +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0008219 +name: cell death +namespace: biological_process +def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant +synonym: "accidental cell death" RELATED [] +synonym: "necrosis" RELATED [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0008220 +name: obsolete necrosis +namespace: biological_process +def: "OBSOLETE. The processes that cause necrosis, the death of tissues, in another organism." [GOC:ma] +comment: This term was made obsolete because the term has been used in the literature by groups in different areas of biology with a number of varying explicit and implicit definitions, and more appropriate terms were created. +synonym: "necrosis" EXACT [] +is_obsolete: true +consider: GO:0001906 +consider: GO:0008219 +consider: GO:0012501 +consider: GO:0019835 +consider: GO:0070265 + +[Term] +id: GO:0008222 +name: obsolete tumor antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "tumor antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0008224 +name: obsolete Gram-positive antibacterial peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "Gram-positive antibacterial peptide activity" EXACT [] +is_obsolete: true +consider: GO:0050830 + +[Term] +id: GO:0008225 +name: obsolete Gram-negative antibacterial peptide activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells." [GOC:go_curators] +comment: This term was made obsolete because it describes involvement in a process and not a function. +synonym: "Gram-negative antibacterial peptide activity" EXACT [] +is_obsolete: true +consider: GO:0050829 + +[Term] +id: GO:0008226 +name: tyramine receptor activity +namespace: molecular_function +def: "Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine." [GOC:curators] +is_a: GO:0008227 ! G protein-coupled amine receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity + +[Term] +id: GO:0008227 +name: G protein-coupled amine receptor activity +namespace: molecular_function +def: "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:dph] +synonym: "amine receptor activity, G-protein coupled" EXACT [GOC:bf] +synonym: "biogenic amine receptor" NARROW [] +synonym: "G-protein coupled amine receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0008228 +name: opsonization +namespace: biological_process +def: "The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody." [GOC:add, GOC:mah, ISBN:0198506732, ISBN:068340007X, ISBN:0781735149] +xref: Wikipedia:Opsonin +is_a: GO:0002252 ! immune effector process +relationship: part_of GO:0006909 ! phagocytosis + +[Term] +id: GO:0008229 +name: obsolete opsonin activity +namespace: molecular_function +def: "OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis." [ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "opsonin activity" EXACT [] +is_obsolete: true +consider: GO:0003823 + +[Term] +id: GO:0008230 +name: ecdysone receptor holocomplex +namespace: cellular_component +def: "A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes." [GOC:bf, PMID:14592980] +is_a: GO:0043235 ! receptor complex +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0008231 +name: repressor ecdysone receptor complex +namespace: cellular_component +def: "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes." [PMID:10488333] +synonym: "repressor ecdysone receptor holocomplex" RELATED [] +is_a: GO:0008230 ! ecdysone receptor holocomplex + +[Term] +id: GO:0008232 +name: activator ecdysone receptor complex +namespace: cellular_component +def: "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes." [PMID:10488333] +synonym: "activator ecdysone receptor holocomplex" RELATED [] +is_a: GO:0008230 ! ecdysone receptor holocomplex + +[Term] +id: GO:0008233 +name: peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_yeast +synonym: "hydrolase, acting on peptide bonds" EXACT [] +synonym: "peptide hydrolase activity" EXACT [] +synonym: "protease activity" EXACT [] +synonym: "proteinase activity" NARROW [] +xref: EC:3.4 +xref: Reactome:R-HSA-205112 "gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6" +xref: Reactome:R-HSA-3000243 "Unknown protease degrades GIF:Cbl to release Cbl" +xref: Reactome:R-HSA-3139027 "Maturation of HIV Virion" +xref: Reactome:R-HSA-376149 "Proteolytic processing of SLIT" +xref: Reactome:R-HSA-448678 "CTSG cleaves CASP1(1-404)" +xref: Reactome:R-HSA-5655483 "USP1 autocleavage" +xref: Reactome:R-HSA-5684864 "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB" +xref: Reactome:R-HSA-5685902 "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC" +xref: Reactome:R-HSA-5693319 "CTRC hydrolyses PRSS1" +is_a: GO:0016787 ! hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006508 ! proteolysis + +[Term] +id: GO:0008234 +name: cysteine-type peptidase activity +namespace: molecular_function +alt_id: GO:0004220 +def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +synonym: "cysteine protease activity" NARROW [] +synonym: "thiol protease activity" NARROW [] +xref: Reactome:R-HSA-2022381 "Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)" +xref: Reactome:R-HSA-2467775 "Autocleavage of ESPL1 (Separase)" +xref: Reactome:R-HSA-2467809 "ESPL1 (Separase) cleaves centromeric cohesin" +xref: Reactome:R-HSA-5660752 "USP9X deubiquitinates Ub-SNCA" +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0008235 +name: metalloexopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE] +is_a: GO:0008237 ! metallopeptidase activity +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0008236 +name: serine-type peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094] +synonym: "serine protease activity" NARROW [] +xref: Reactome:R-HSA-1461993 "pro-HD5 is cleaved by trypsin" +xref: Reactome:R-HSA-2022383 "Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)" +xref: Reactome:R-HSA-3132753 "Pancreatic proteases degrade TCN1:Cbl" +xref: Reactome:R-HSA-6801766 "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)" +is_a: GO:0017171 ! serine hydrolase activity +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0008237 +name: metallopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +synonym: "metalloprotease activity" NARROW [GOC:mah] +synonym: "metalloproteinase activity" NARROW [GOC:mah] +xref: Reactome:R-HSA-157629 "NOTCH2-ligand complex is cleaved to produce NEXT2" +xref: Reactome:R-HSA-157632 "Complex of NOTCH1 with its ligand is cleaved to produce NEXT1" +xref: Reactome:R-HSA-193679 "alpha-secretase cleaves the p75NTR extracellular domain" +xref: Reactome:R-HSA-2022368 "Neprilysin hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)" +xref: Reactome:R-HSA-2022393 "ANPEP hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8)" +xref: Reactome:R-HSA-2022396 "Neprilysin hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-7)" +xref: Reactome:R-HSA-2022399 "ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8)" +xref: Reactome:R-HSA-2220944 "ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants" +xref: Reactome:R-HSA-2220976 "NOTCH1 HD+PEST domain mutants are cleaved by ADAM10/17 irrespective of ligand binding" +xref: Reactome:R-HSA-2666278 "NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1" +xref: Reactome:R-HSA-2730752 "NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding" +xref: Reactome:R-HSA-3928660 "ADAM10 cleaves EFNAs" +xref: Reactome:R-HSA-5211340 "Anthrax LF cleaves target cell MAP2K1 (MEK1)" +xref: Reactome:R-HSA-5211356 "Anthrax LF cleaves target cell MAP2K2 (MEK2)" +xref: Reactome:R-HSA-5211387 "Anthrax LF cleaves target cell MAP2K7 (MEK7)" +xref: Reactome:R-HSA-5211391 "Anthrax LF cleaves target cell MAP2K4 (MEK4)" +xref: Reactome:R-HSA-5211400 "Anthrax LF cleaves target cell MAP2K3 (MEK3)" +xref: Reactome:R-HSA-5211405 "Anthrax LF cleaves target cell MAP2K6 (MEK6)" +xref: Reactome:R-HSA-8986181 "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)" +xref: Reactome:R-HSA-9013284 "NOTCH3-ligand complex is cleaved to produce NEXT3" +xref: Reactome:R-HSA-9604264 "ADAM10 cleaves NOTCH4" +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0008238 +name: exopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both." [http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE] +synonym: "exoprotease activity" NARROW [] +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0008239 +name: dipeptidyl-peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain." [GOC:mb] +is_a: GO:0004177 ! aminopeptidase activity + +[Term] +id: GO:0008240 +name: tripeptidyl-peptidase activity +namespace: molecular_function +def: "Catalysis of the release of an N-terminal tripeptide from a polypeptide." [GOC:mah] +xref: EC:3.4.14 +xref: MetaCyc:3.4.14.10-RXN +xref: MetaCyc:3.4.14.9-RXN +is_a: GO:0008236 ! serine-type peptidase activity +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0008241 +name: peptidyl-dipeptidase activity +namespace: molecular_function +def: "Catalysis of the release of C-terminal dipeptides from a polypeptide chain." [GOC:mb] +xref: EC:3.4.15 +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0008242 +name: omega peptidase activity +namespace: molecular_function +def: "Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups)." [EC:3.4.19.-] +synonym: "peptidase activity, acting on peptides containing modified amino acids" RELATED [] +xref: EC:3.4.19 +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0008243 +name: obsolete plasminogen activator activity +namespace: molecular_function +alt_id: GO:0004296 +alt_id: GO:0004297 +def: "OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin." [EC:3.4.21.68, EC:3.4.21.73] +comment: This term was made obsolete because it represents a gene product. +synonym: "abbokinase activity" EXACT [EC:3.4.21.68] +synonym: "cellular plasminogen activator activity" NARROW [EC:3.4.21.-] +synonym: "double-chain urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] +synonym: "plasminogen activator activity" EXACT [] +synonym: "plasminogen activator, tissue-type" RELATED [EC:3.4.21.68] +synonym: "t-PA" RELATED [EC:3.4.21.68] +synonym: "t-plasminogen activator activity" NARROW [] +synonym: "tissue plasminogen activator activity" NARROW [EC:3.4.21.-] +synonym: "tissue-type plasminogen activator activity" RELATED [EC:3.4.21.-] +synonym: "tPA activity" NARROW [EC:3.4.21.-] +synonym: "two-chain urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] +synonym: "u-PA" RELATED [EC:3.4.21.68] +synonym: "u-plasminogen activator activity" NARROW [] +synonym: "uPA" RELATED [EC:3.4.21.68] +synonym: "urinary esterase A" RELATED [EC:3.4.21.68] +synonym: "urinary plasminogen activator activity" NARROW [EC:3.4.21.-] +synonym: "urokinase activity" RELATED [EC:3.4.21.-] +synonym: "urokinase plasminogen activator" RELATED [EC:3.4.21.68] +synonym: "urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] +xref: EC:3.4.21.68 +xref: EC:3.4.21.73 +xref: MetaCyc:3.4.21.68-RXN +xref: MetaCyc:3.4.21.73-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008245 +name: obsolete lysosomal membrane hydrogen-transporting ATPase +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "lysosomal membrane hydrogen-transporting ATPase" EXACT [] +synonym: "V-ATPase" RELATED [] +is_obsolete: true +consider: GO:0046611 + +[Term] +id: GO:0008246 +name: obsolete electron transfer flavoprotein +namespace: molecular_function +def: "OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system." [ISBN:0198506732] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "electron transfer flavoprotein" EXACT [] +synonym: "ETF" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0008247 +name: 1-alkyl-2-acetylglycerophosphocholine esterase complex +namespace: cellular_component +def: "An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF)." [GOC:jl, PMID:10542206] +comment: See also the molecular function term '1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847'. +synonym: "2-acetyl-1-alkylglycerophosphocholine esterase complex" EXACT [] +synonym: "platelet-activating factor acetylhydrolase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0008248 +name: obsolete pre-mRNA splicing factor activity +namespace: molecular_function +def: "OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA." [GOC:jl] +comment: This term was made obsolete because it describes a biological process. +synonym: "pre-mRNA splicing factor activity" EXACT [] +is_obsolete: true +consider: GO:0008380 + +[Term] +id: GO:0008250 +name: oligosaccharyltransferase complex +namespace: cellular_component +def: "A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected." [ISBN:0879695595, PMID:15835887] +synonym: "oligosaccharyl transferase complex" EXACT [] +synonym: "OST complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0008251 +name: tRNA-specific adenosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule." [GOC:mah] +synonym: "tRNA-adenosine deaminase activity" EXACT [] +xref: Reactome:R-HSA-6782311 "ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs" +xref: Reactome:R-HSA-6782336 "ADAT1 deaminates adenosine-37 in tRNA(Ala)" +is_a: GO:0004000 ! adenosine deaminase activity + +[Term] +id: GO:0008252 +name: nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate." [EC:3.1.3.31] +synonym: "acid nucleotidase activity" EXACT [EC:3.1.3.31] +synonym: "deoxyinosine-activated nucleotidase (DIAN)" EXACT [EC:3.1.3.31] +synonym: "deoxyribonucleoside-activated nucleotidase (DAN)" EXACT [EC:3.1.3.31] +synonym: "NSP I" RELATED [EC:3.1.3.31] +synonym: "NSP II" RELATED [EC:3.1.3.31] +synonym: "nucleotide phosphohydrolase activity" EXACT [EC:3.1.3.31] +synonym: "nucleotide-specific phosphatase activity" EXACT [EC:3.1.3.31] +xref: EC:3.1.3.31 +xref: MetaCyc:NUCLEOTIDASE-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0008253 +name: 5'-nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate." [EC:3.1.3.5] +synonym: "5' nucleotidase activity" EXACT [] +synonym: "5'-adenylic phosphatase" NARROW [EC:3.1.3.5] +synonym: "5'-AMP nucleotidase" NARROW [EC:3.1.3.5] +synonym: "5'-AMPase" NARROW [EC:3.1.3.5] +synonym: "5'-mononucleotidase activity" EXACT [EC:3.1.3.5] +synonym: "5'-ribonucleotide phosphohydrolase activity" EXACT [EC:3.1.3.5] +synonym: "adenosine 5'-phosphatase" NARROW [EC:3.1.3.5] +synonym: "adenosine monophosphatase" NARROW [EC:3.1.3.5] +synonym: "AMP phosphatase" NARROW [EC:3.1.3.5] +synonym: "AMP phosphohydrolase" NARROW [EC:3.1.3.5] +synonym: "AMPase" NARROW [EC:3.1.3.5] +synonym: "snake venom 5'-nucleotidase" NARROW [EC:3.1.3.5] +synonym: "thimidine monophosphate nucleotidase" NARROW [EC:3.1.3.5] +synonym: "UMPase" NARROW [EC:3.1.3.5] +synonym: "uridine 5'-nucleotidase" NARROW [EC:3.1.3.5] +xref: EC:3.1.3.5 +xref: MetaCyc:5-NUCLEOTID-RXN +xref: Reactome:R-HSA-109278 "NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP" +xref: Reactome:R-HSA-109291 "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E]" +xref: Reactome:R-HSA-109380 "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)" +xref: Reactome:R-HSA-109387 "(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)" +xref: Reactome:R-HSA-109415 "AMP + H2O => adenosine + orthophosphate [NT5C1B]" +xref: Reactome:R-HSA-109449 "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3)" +xref: Reactome:R-HSA-109470 "(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)" +xref: Reactome:R-HSA-109480 "TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C]" +xref: Reactome:R-HSA-109514 "TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M]" +xref: Reactome:R-HSA-5694126 "NT5C3B hydrolyses 7MGP to 7MG" +xref: Reactome:R-HSA-74248 "(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2)" +xref: Reactome:R-HSA-8940070 "NT5E:Zn2+ hydrolyses NAD+" +xref: Reactome:R-HSA-8940074 "NT5E:Zn2+ hydrolyses NMN" +is_a: GO:0008252 ! nucleotidase activity + +[Term] +id: GO:0008254 +name: 3'-nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate." [EC:3.1.3.6] +synonym: "3' nucleotidase activity" EXACT [] +synonym: "3'-mononucleotidase activity" EXACT [EC:3.1.3.6] +synonym: "3'-phosphatase activity" EXACT [EC:3.1.3.6] +synonym: "3'-ribonucleotidase activity" EXACT [EC:3.1.3.6] +synonym: "3'-ribonucleotide phosphohydrolase activity" EXACT [EC:3.1.3.6] +xref: EC:3.1.3.6 +xref: MetaCyc:3-NUCLEOTID-RXN +is_a: GO:0008252 ! nucleotidase activity + +[Term] +id: GO:0008255 +name: ecdysis-triggering hormone activity +namespace: molecular_function +def: "The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system." [GOC:mah, PMID:9020043] +is_a: GO:0005184 ! neuropeptide hormone activity + +[Term] +id: GO:0008256 +name: protein histidine pros-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine." [EC:2.7.13.1] +synonym: "ATP:protein-L-histidine N-pros-phosphotransferase activity" EXACT [EC:2.7.13.1] +synonym: "ATP:protein-L-histidine Npi-phosphotransferase activity" EXACT [EC:2.7.13.1] +synonym: "HK2" RELATED [EC:2.7.13.1] +synonym: "protein-histidine pros-kinase activity" EXACT [EC:2.7.13.1] +xref: EC:2.7.13.1 +xref: MetaCyc:2.7.13.1-RXN +is_a: GO:0004673 ! protein histidine kinase activity + +[Term] +id: GO:0008257 +name: protein histidine tele-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine." [EC:2.7.13.2] +synonym: "ATP:protein-L-histidine N-tele-phosphotransferase activity" EXACT [EC:2.7.13.2] +synonym: "ATP:protein-L-histidine Ntau-phosphotransferase activity" EXACT [EC:2.7.13.2] +synonym: "HK3" RELATED [EC:2.7.13.2] +synonym: "protein-histidine tele-kinase activity" EXACT [EC:2.7.13.2] +xref: EC:2.7.13.2 +xref: MetaCyc:2.7.13.2-RXN +is_a: GO:0004673 ! protein histidine kinase activity + +[Term] +id: GO:0008258 +name: head involution +namespace: biological_process +def: "Movement of the anterior ectoderm to the interior of the embryo." [ISBN:0879694238] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0008259 +name: obsolete transforming growth factor beta ligand binding to type I receptor +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a function. +synonym: "TGF-beta ligand binding to type I receptor" EXACT [] +synonym: "TGFbeta ligand binding to type I receptor" EXACT [] +synonym: "transforming growth factor beta ligand binding to type I receptor" EXACT [] +is_obsolete: true +consider: GO:0005025 +consider: GO:0005160 +consider: GO:0050431 + +[Term] +id: GO:0008260 +name: 3-oxoacid CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA." [EC:2.8.3.5] +synonym: "3-ketoacid CoA-transferase activity" EXACT [EC:2.8.3.5] +synonym: "3-ketoacid coenzyme A transferase activity" EXACT [EC:2.8.3.5] +synonym: "3-oxo-CoA transferase activity" EXACT [EC:2.8.3.5] +synonym: "3-oxoacid CoA dehydrogenase activity" EXACT [EC:2.8.3.5] +synonym: "3-oxoacid coenzyme A-transferase activity" EXACT [EC:2.8.3.5] +synonym: "acetoacetate succinyl-CoA transferase activity" EXACT [EC:2.8.3.5] +synonym: "acetoacetyl coenzyme A-succinic thiophorase activity" EXACT [EC:2.8.3.5] +synonym: "succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity" EXACT [EC:2.8.3.5] +synonym: "succinyl-CoA transferase activity" EXACT [EC:2.8.3.5] +synonym: "succinyl-CoA:3-ketoacid-CoA transferase activity" EXACT [EC:2.8.3.5] +synonym: "succinyl-CoA:3-oxo-acid CoA-transferase activity" EXACT [EC:2.8.3.5] +xref: EC:2.8.3.5 +xref: MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN +xref: Reactome:R-HSA-74177 "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA" +xref: RHEA:25480 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0008261 +name: allatostatin receptor activity +namespace: molecular_function +def: "Combining with allatostatin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0008263 +name: pyrimidine-specific mismatch base pair DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site." [GOC:elh, PMID:9224623] +synonym: "G/T-mismatch-specific thymine-DNA glycosylase activity" EXACT [] +is_a: GO:0000700 ! mismatch base pair DNA N-glycosylase activity + +[Term] +id: GO:0008265 +name: Mo-molybdopterin cofactor sulfurase activity +namespace: molecular_function +def: "Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase." [GOC:mah, PMID:11549764] +synonym: "Mo-molybdopterin cofactor sulphurase activity" EXACT [] +synonym: "molybdopterin cofactor sulfurase activity" EXACT [] +synonym: "molybdopterin synthase sulfurylase activity" EXACT [] +xref: EC:2.8.1.9 +xref: Reactome:R-HSA-947499 "Exchange of oxygen with sulfur in MoCo" +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0008266 +name: poly(U) RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule." [GOC:mah] +synonym: "poly(U) binding" EXACT [GOC:mah] +is_a: GO:0008187 ! poly-pyrimidine tract binding + +[Term] +id: GO:0008267 +name: poly-glutamine tract binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein." [GOC:mah] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0008268 +name: obsolete receptor signaling protein tyrosine kinase signaling protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information. +synonym: "receptor signaling protein tyrosine kinase signaling protein activity" EXACT [] +synonym: "receptor signalling protein tyrosine kinase signalling protein activity" EXACT [] +is_obsolete: true +consider: GO:0035556 + +[Term] +id: GO:0008269 +name: JAK pathway signal transduction adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07] +is_a: GO:0035591 ! signaling adaptor activity +relationship: part_of GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0008270 +name: zinc ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with zinc (Zn) ions." [GOC:ai] +synonym: "zinc binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0008271 +name: secondary active sulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "secondary active sulphate transmembrane transporter activity" EXACT [] +synonym: "sulfate porter activity" RELATED [] +synonym: "sulphate porter activity" EXACT [] +is_a: GO:0015116 ! sulfate transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0008272 +name: sulfate transport +namespace: biological_process +alt_id: GO:0006870 +def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "sulphate transport" EXACT [] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0008273 +name: calcium, potassium:sodium antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in)." [TC:2.A.19.4.1] +synonym: "potassium-dependent sodium/calcium exchanger" RELATED [] +xref: Reactome:R-HSA-2514891 "SLC24A1 exchanges 4Na+ for Ca2+, K+" +xref: Reactome:R-HSA-425678 "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+" +xref: Reactome:R-HSA-5625841 "Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+" +xref: Reactome:R-HSA-5626270 "Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+" +xref: Reactome:R-HSA-5626316 "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+" +xref: Reactome:R-HSA-5626356 "Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+" +is_a: GO:0005432 ! calcium:sodium antiporter activity +is_a: GO:0022821 ! potassium ion antiporter activity + +[Term] +id: GO:0008274 +name: gamma-tubulin ring complex +namespace: cellular_component +def: "A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins that forms a flexible open ring structure thought to be the unit of nucleation at the minus end of a microtubule." [GOC:clt, PMID:12134075] +synonym: "gammaTuRC" EXACT [] +is_a: GO:0000931 ! gamma-tubulin large complex + +[Term] +id: GO:0008275 +name: gamma-tubulin small complex +namespace: cellular_component +def: "A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex." [PMID:11297925, PMID:12134075] +synonym: "gammaTuSC" EXACT [] +is_a: GO:0000930 ! gamma-tubulin complex + +[Term] +id: GO:0008276 +name: protein methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group (CH3-) to a protein." [GOC:jl, ISBN:0198506732] +xref: Reactome:R-HSA-9632182 "PRMT1 methylates ESRs" +is_a: GO:0008168 ! methyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006479 ! protein methylation + +[Term] +id: GO:0008277 +name: regulation of G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway." [GOC:go_curators] +synonym: "regulation of G protein coupled receptor protein signaling pathway" EXACT [] +synonym: "regulation of G protein coupled receptor protein signalling pathway" EXACT [] +synonym: "regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "regulation of G-protein coupled receptor protein signalling pathway" EXACT [] +synonym: "regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] +synonym: "regulation of GPCR protein signaling pathway" EXACT [] +synonym: "regulation of GPCR protein signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: regulates GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0008278 +name: cohesin complex +namespace: cellular_component +alt_id: GO:0008279 +alt_id: GO:0008280 +alt_id: GO:0043222 +def: "A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3)." [GOC:jl, GOC:sp, GOC:vw, PMID:9887095] +subset: goslim_pir +synonym: "14S cohesin" NARROW [] +synonym: "9S cohesin" NARROW [] +synonym: "cohesin core heterodimer" RELATED [] +synonym: "SMC complex" RELATED [] +synonym: "SMC/kleisin ring complex" EXACT [] +synonym: "Smc1-Smc3 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000793 ! condensed chromosome + +[Term] +id: GO:0008281 +name: sulfonylurea receptor activity +namespace: molecular_function +def: "Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:ai, GOC:signaling] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'potassium channel activity ; GO:0005267'. +synonym: "sulphonylurea receptor activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0008282 +name: inward rectifying potassium channel +namespace: cellular_component +def: "A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity." [GOC:bhm, PMID:16308567, PMID:16956886] +synonym: "ATP-sensitive potassium channel complex" EXACT [] +synonym: "inward rectifying K+ channel" EXACT [] +synonym: "KCNJ11-SUR complex" RELATED [] +synonym: "KCNJ11-SURx complex" RELATED [] +synonym: "KCNJ8-SUR complex" RELATED [] +synonym: "KCNJ8-SURx complex" RELATED [] +synonym: "Kir6-SUR complex" RELATED [] +synonym: "Kir6.1-SUR complex" RELATED [] +synonym: "Kir6.1-SURx complex" RELATED [] +synonym: "Kir6.2-SUR complex" RELATED [] +synonym: "Kir6.2-SURx complex" RELATED [] +synonym: "Kir6.x complex" RELATED [] +synonym: "Kir6.x-SURx complex" RELATED [] +is_a: GO:0034705 ! potassium channel complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0008283 +name: cell population proliferation +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] +comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +synonym: "cell proliferation" RELATED [] +is_a: GO:0009987 ! cellular process +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0008284 +name: positive regulation of cell population proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] +synonym: "activation of cell proliferation" NARROW [] +synonym: "positive regulation of cell proliferation" RELATED [] +synonym: "stimulation of cell proliferation" NARROW [] +synonym: "up regulation of cell proliferation" EXACT [] +synonym: "up-regulation of cell proliferation" EXACT [] +synonym: "upregulation of cell proliferation" EXACT [] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008283 ! cell population proliferation +relationship: positively_regulates GO:0008283 ! cell population proliferation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0008285 +name: negative regulation of cell population proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] +synonym: "down regulation of cell proliferation" EXACT [] +synonym: "down-regulation of cell proliferation" EXACT [] +synonym: "downregulation of cell proliferation" EXACT [] +synonym: "inhibition of cell proliferation" NARROW [] +synonym: "negative regulation of cell proliferation" RELATED [] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008283 ! cell population proliferation +relationship: negatively_regulates GO:0008283 ! cell population proliferation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0008286 +name: insulin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin." [GOC:ceb] +synonym: "daf-2 receptor signaling pathway" NARROW [] +synonym: "insulin receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +relationship: part_of GO:0032869 ! cellular response to insulin stimulus + +[Term] +id: GO:0008287 +name: protein serine/threonine phosphatase complex +namespace: cellular_component +def: "A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein." [GOC:bf] +subset: goslim_pir +is_a: GO:1903293 ! phosphatase complex + +[Term] +id: GO:0008288 +name: boss receptor activity +namespace: molecular_function +def: "Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [GOC:jl, GOC:signaling] +synonym: "sevenless receptor activity" RELATED [] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity + +[Term] +id: GO:0008289 +name: lipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipid." [GOC:ai] +subset: goslim_agr +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +is_a: GO:0005488 ! binding + +[Term] +id: GO:0008290 +name: F-actin capping protein complex +namespace: cellular_component +def: "A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments." [GOC:go_curators, ISBN:0198599560] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0008291 +name: acetylcholine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] +synonym: "acetylcholine metabolism" EXACT [] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:1900619 ! acetate ester metabolic process + +[Term] +id: GO:0008292 +name: acetylcholine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] +synonym: "acetylcholine anabolism" EXACT [] +synonym: "acetylcholine biosynthesis" EXACT [] +synonym: "acetylcholine formation" EXACT [] +synonym: "acetylcholine synthesis" EXACT [] +is_a: GO:0008291 ! acetylcholine metabolic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:1900620 ! acetate ester biosynthetic process + +[Term] +id: GO:0008293 +name: torso signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:8343949] +synonym: "torso signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0008294 +name: calcium- and calmodulin-responsive adenylate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin." [EC:4.6.1.1, GOC:mah] +synonym: "calcium- and calmodulin-responsive adenylyl cyclase activity" EXACT [] +synonym: "calcium/calmodulin-responsive adenylate cyclase activity" EXACT [] +xref: Reactome:R-HSA-111930 "Adenylate cyclase produces cAMP" +xref: Reactome:R-HSA-442715 "Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP" +is_a: GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0008295 +name: spermidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:go_curators, ISBN:0198506732] +synonym: "spermidine anabolism" EXACT [] +synonym: "spermidine biosynthesis" EXACT [] +synonym: "spermidine formation" EXACT [] +synonym: "spermidine synthesis" EXACT [] +xref: MetaCyc:BSUBPOLYAMSYN-PWY +xref: MetaCyc:POLYAMINSYN3-PWY +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:0008216 ! spermidine metabolic process + +[Term] +id: GO:0008296 +name: 3'-5'-exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule." [GOC:mah] +synonym: "3'-5' exodeoxyribonuclease activity" EXACT [] +xref: Reactome:R-HSA-9023943 "MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end" +is_a: GO:0008408 ! 3'-5' exonuclease activity +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008297 +name: single-stranded DNA exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule." [GOC:mah] +synonym: "single-stranded DNA specific exodeoxyribonuclease activity" RELATED [] +synonym: "ssDNA-specific exodeoxyribonuclease activity" RELATED [GOC:mah] +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008298 +name: intracellular mRNA localization +namespace: biological_process +def: "Any process in which mRNA is transported to, or maintained in, a specific location within the cell." [GOC:ai] +synonym: "establishment and maintenance of intracellular RNA localization" EXACT [] +synonym: "intracellular mRNA localisation" EXACT [GOC:mah] +synonym: "intracellular mRNA positioning" NARROW [] +synonym: "mRNA localization, intracellular" EXACT [] +synonym: "mRNA positioning, intracellular" NARROW [] +is_a: GO:0006403 ! RNA localization +is_a: GO:0070727 ! cellular macromolecule localization + +[Term] +id: GO:0008299 +name: isoprenoid biosynthetic process +namespace: biological_process +alt_id: GO:0009241 +def: "The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732] +synonym: "isoprenoid anabolism" EXACT [] +synonym: "isoprenoid biosynthesis" EXACT [] +synonym: "isoprenoid formation" EXACT [] +synonym: "isoprenoid synthesis" EXACT [] +synonym: "polyisoprenoid anabolism" NARROW [] +synonym: "polyisoprenoid biosynthesis" NARROW [] +synonym: "polyisoprenoid biosynthetic process" NARROW [] +synonym: "polyisoprenoid formation" NARROW [] +synonym: "polyisoprenoid synthesis" NARROW [] +synonym: "polyterpene biosynthesis" NARROW [] +synonym: "polyterpene biosynthetic process" NARROW [] +xref: MetaCyc:POLYISOPRENSYN-PWY +is_a: GO:0006720 ! isoprenoid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0008300 +name: isoprenoid catabolic process +namespace: biological_process +alt_id: GO:0016097 +def: "The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [ISBN:0198506732] +synonym: "isoprenoid breakdown" EXACT [] +synonym: "isoprenoid catabolism" EXACT [] +synonym: "isoprenoid degradation" EXACT [] +synonym: "polyisoprenoid breakdown" NARROW [] +synonym: "polyisoprenoid catabolic process" NARROW [] +synonym: "polyisoprenoid catabolism" NARROW [] +synonym: "polyisoprenoid degradation" NARROW [] +synonym: "polyterpene catabolic process" NARROW [] +synonym: "polyterpene catabolism" NARROW [] +is_a: GO:0006720 ! isoprenoid metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process + +[Term] +id: GO:0008301 +name: DNA binding, bending +namespace: molecular_function +def: "The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:krc, GOC:vw, PMID:10710711, PMID:19037758] +synonym: "DNA bending activity" EXACT [] +synonym: "DNA bending involving DNA binding" EXACT [] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0008302 +name: female germline ring canal formation, actin assembly +namespace: biological_process +def: "Recruitment and organization of actin filaments in female germline ring canals." [ISBN:0879694238] +synonym: "nurse cell ring canal formation, actin assembly" NARROW [] +synonym: "ovarian ring canal formation, actin assembly" NARROW [] +synonym: "ring canal formation, actin assembly" BROAD [] +is_a: GO:0007015 ! actin filament organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007301 ! female germline ring canal formation + +[Term] +id: GO:0008303 +name: caspase complex +namespace: cellular_component +def: "A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes." [GOC:cna, GOC:mtg_apoptosis, PMID:15569692] +comment: Note that this term was reinstated from obsolete. +synonym: "cysteine-type endopeptidase complex" EXACT [GOC:pr] +is_a: GO:1905369 ! endopeptidase complex + +[Term] +id: GO:0008304 +name: obsolete eukaryotic translation initiation factor 4 complex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "eIF-4" EXACT [] +synonym: "eukaryotic translation initiation factor 4 complex" EXACT [] +is_obsolete: true +replaced_by: GO:0016281 + +[Term] +id: GO:0008305 +name: integrin complex +namespace: cellular_component +def: "A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands." [PMID:17543136] +synonym: "laminin receptor protein" RELATED [] +is_a: GO:0098636 ! protein complex involved in cell adhesion +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0008306 +name: associative learning +namespace: biological_process +def: "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." [ISBN:0582227089] +synonym: "classical conditioning" EXACT [] +synonym: "conditional learning" EXACT [] +synonym: "conditional response" EXACT [] +synonym: "Pavlovian conditioning" EXACT [] +xref: Wikipedia:Learning#Associative_learning +is_a: GO:0007612 ! learning + +[Term] +id: GO:0008307 +name: structural constituent of muscle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a muscle fiber." [GOC:mah] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0008308 +name: voltage-gated anion channel activity +namespace: molecular_function +alt_id: GO:0022844 +def: "Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, GOC:vw, ISBN:0815340729] +synonym: "voltage-dependent ion-selective channel activity" RELATED [] +synonym: "voltage-gated ion-selective channel activity" RELATED [] +xref: Reactome:R-HSA-9012374 "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space" +is_a: GO:0005244 ! voltage-gated ion channel activity +is_a: GO:0005253 ! anion channel activity + +[Term] +id: GO:0008309 +name: double-stranded DNA exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule." [GOC:mah] +synonym: "double-stranded DNA specific exodeoxyribonuclease activity" RELATED [] +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008310 +name: single-stranded DNA 3'-5' exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule." [GOC:mah, PMID:22562358] +synonym: "single-stranded DNA specific 3'-5' exodeoxyribonuclease activity" RELATED [] +synonym: "ssDNA-specific 3'-5' exodeoxyribonuclease activity" RELATED [GOC:mah] +is_a: GO:0008296 ! 3'-5'-exodeoxyribonuclease activity +is_a: GO:0008297 ! single-stranded DNA exodeoxyribonuclease activity + +[Term] +id: GO:0008311 +name: double-stranded DNA 3'-5' exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule." [GOC:mah, PMID:22562358] +synonym: "double-stranded DNA specific 3'-5' exodeoxyribonuclease activity" RELATED [] +is_a: GO:0008296 ! 3'-5'-exodeoxyribonuclease activity +is_a: GO:0008309 ! double-stranded DNA exodeoxyribonuclease activity + +[Term] +id: GO:0008312 +name: 7S RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP)." [GOC:jl, PMID:6181418] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0008313 +name: gurken-activated receptor activity +namespace: molecular_function +def: "Combining with the ligand Gurken to initiate a change in cell activity." [GOC:bf] +synonym: "gurken receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0005006 ! epidermal growth factor-activated receptor activity + +[Term] +id: GO:0008314 +name: gurken signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken." [GOC:bf, PMID:23972992] +synonym: "gurken receptor signaling pathway" EXACT [] +synonym: "gurken receptor signalling pathway" EXACT [] +synonym: "gurken-activated signaling pathway" RELATED [GOC:signaling] +synonym: "signaling by Gurken" EXACT [GOC:bf] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway + +[Term] +id: GO:0008315 +name: G2/MI transition of meiotic cell cycle +namespace: biological_process +def: "The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I." [PMID:15084480] +synonym: "meiotic cell cycle G2/MI phase transition" EXACT [] +synonym: "meiotic G2/MI phase transition" EXACT [] +synonym: "meiotic G2/MI transition" EXACT [] +is_a: GO:0044771 ! meiotic cell cycle phase transition +is_a: GO:0044839 ! cell cycle G2/M phase transition +is_a: GO:0061982 ! meiosis I cell cycle process + +[Term] +id: GO:0008316 +name: structural constituent of vitelline membrane +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:sensu] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0008317 +name: gurken receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the gurken growth factor receptor." [GOC:ai] +synonym: "gurken receptor ligand" NARROW [] +is_a: GO:0005154 ! epidermal growth factor receptor binding + +[Term] +id: GO:0008318 +name: protein prenyltransferase activity +namespace: molecular_function +alt_id: GO:0008244 +def: "Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein." [GOC:mah] +is_a: GO:0004659 ! prenyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008319 +name: obsolete prenyl protein specific endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "prenyl protein specific endopeptidase activity" EXACT [] +xref: EC:3.4.24 +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008320 +name: protein transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015266 +alt_id: GO:0015463 +def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl] +synonym: "protein channel activity" RELATED [] +xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space" +xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochndrial intermebrane space to the mitochondrial matrix" +xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria" +xref: Reactome:R-HSA-5210943 "PA63:ANTRX2 oligomer transports EF and LF (target cell endosome to cytosol)" +xref: Reactome:R-HSA-5210947 "PA63:ANTRX1 oligomer transports EF and LF (target cell endosome to cytosol)" +xref: Reactome:R-HSA-5228406 "TeNT HC transports TeNT LC from target cell endosome membrane into cytosol" +xref: Reactome:R-HSA-5244404 "BoNT/B HC transports BoNT/B LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5244428 "BoNT/A HC transports BoNT/A LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5244506 "BoNT/E HC transports BoNT/E LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5246514 "BoNT/C HC transports BoNT/C LC from target cell synaptic vesicle membrane to cytosol" +xref: Reactome:R-HSA-5250616 "BoNT/D HC transports BoNT/D LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5250884 "BoNT/F HC transports BoNT/F LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5250972 "BoNT/G HC transports BoNT/G LC from target cell synaptic vesicle membrane into cytosol" +xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane" +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:0140318 ! protein transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0008321 +name: Ral guanyl-nucleotide exchange factor activity +namespace: molecular_function +alt_id: GO:0016220 +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +synonym: "Ral GDP-dissociation stimulator activity" EXACT [] +xref: Reactome:R-HSA-171026 "Guanine nucleotide exchange on RAL" +is_a: GO:0005088 ! Ras guanyl-nucleotide exchange factor activity +is_a: GO:0017160 ! Ral GTPase binding + +[Term] +id: GO:0008322 +name: obsolete Pro-X carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "Pro-X carboxypeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030536 + +[Term] +id: GO:0008324 +name: cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] +synonym: "transmembrane cation transporter activity" EXACT [] +is_a: GO:0015075 ! ion transmembrane transporter activity +relationship: part_of GO:0098655 ! cation transmembrane transport + +[Term] +id: GO:0008327 +name: methyl-CpG binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide." [GOC:jl, PMID:11746232] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0043565 ! sequence-specific DNA binding + +[Term] +id: GO:0008328 +name: ionotropic glutamate receptor complex +namespace: cellular_component +def: "A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html] +is_a: GO:0034702 ! ion channel complex +is_a: GO:0098878 ! neurotransmitter receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0008330 +name: protein tyrosine/threonine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [GOC:mah] +xref: EC:3.1.3 +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0008331 +name: high voltage-gated calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729, PMID:16382099] +synonym: "high voltage gated calcium channel activity" EXACT [] +synonym: "high voltage-dependent calcium channel activity" EXACT [] +synonym: "L-type calcium channel" RELATED [] +synonym: "N-type calcium channel" RELATED [] +synonym: "P-type calcium channel" RELATED [] +synonym: "Q-type calcium channel" RELATED [] +is_a: GO:0005245 ! voltage-gated calcium channel activity + +[Term] +id: GO:0008332 +name: low voltage-gated calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729, PMID:16382099] +synonym: "low voltage gated calcium channel activity" EXACT [] +synonym: "low voltage-dependent calcium channel activity" EXACT [] +synonym: "T-type calcium channel" RELATED [] +is_a: GO:0005245 ! voltage-gated calcium channel activity + +[Term] +id: GO:0008333 +name: endosome to lysosome transport +namespace: biological_process +def: "The directed movement of substances from endosomes to lysosomes." [GOC:ai, ISBN:0716731363] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0008334 +name: histone mRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an mRNA encoding a histone." [GOC:krc, GOC:mah, PMID:17855393] +comment: In higher Eukaryotes, histone mRNAs (stem-loop containing) are non-polyadenylated and thus have a different form of 3'-end regulation to other mRNAs. In lower Eukaryotes, the 3'-ends of histone mRNAs are polyadenylated. +synonym: "histone mRNA metabolism" EXACT [] +synonym: "stem-loop-containing histone mRNA 3'-end processing" NARROW [GOC:krc, GOC:mah, PMID:17855393] +is_a: GO:0016071 ! mRNA metabolic process + +[Term] +id: GO:0008335 +name: female germline ring canal stabilization +namespace: biological_process +def: "Maintenance of the structural integrity of the ring canals connecting the female germline cyst." [GOC:curators] +synonym: "nurse cell ring canal stabilization" NARROW [] +synonym: "ovarian ring canal stabilization" NARROW [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0031032 ! actomyosin structure organization +relationship: part_of GO:0007300 ! ovarian nurse cell to oocyte transport + +[Term] +id: GO:0008336 +name: gamma-butyrobetaine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate." [EC:1.14.11.1, RHEA:24028] +synonym: "4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.1] +synonym: "alpha-butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] +synonym: "butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] +synonym: "g-butyrobetaine dioxygenase activity" EXACT [] +synonym: "gamma-BBH activity" EXACT [EC:1.14.11.1] +synonym: "gamma-butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] +synonym: "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity" EXACT [] +xref: EC:1.14.11.1 +xref: KEGG_REACTION:R02397 +xref: MetaCyc:1.14.11.1-RXN +xref: Reactome:R-HSA-71261 "BBOX1:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA" +xref: RHEA:24028 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0008337 +name: obsolete selectin +namespace: molecular_function +def: "OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins." [ISBN:0124325653] +comment: This term was made obsolete because it describes a class of gene products. +synonym: "selectin" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0007155 +consider: GO:0016021 +consider: GO:0030246 +consider: GO:0050839 + +[Term] +id: GO:0008340 +name: determination of adult lifespan +namespace: biological_process +def: "The control of viability and duration in the adult phase of the life-cycle." [GOC:ems] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0010259 ! multicellular organism aging + +[Term] +id: GO:0008341 +name: obsolete response to cocaine (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557)." [GOC:go_curators, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "response to cocaine (sensu Insecta)" EXACT [] +is_obsolete: true +consider: GO:0048148 + +[Term] +id: GO:0008342 +name: obsolete larval feeding behavior (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. Feeding behavior in an insect larva." [GOC:jid, GOC:mah] +comment: This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term. +synonym: "larval feeding behavior (sensu Insecta)" EXACT [] +is_obsolete: true +replaced_by: GO:0030536 + +[Term] +id: GO:0008343 +name: adult feeding behavior +namespace: biological_process +def: "Feeding behavior in a fully developed and mature organism." [GOC:mah] +comment: See also the biological process term 'feeding behavior ; GO:0007631'. +synonym: "adult feeding behaviour" EXACT [] +is_a: GO:0007631 ! feeding behavior +is_a: GO:0030534 ! adult behavior + +[Term] +id: GO:0008344 +name: adult locomotory behavior +namespace: biological_process +def: "Locomotory behavior in a fully developed and mature organism." [GOC:ai] +comment: See also the biological process term 'locomotory behavior ; GO:0007626'. +synonym: "adult locomotory behaviour" EXACT [] +is_a: GO:0007626 ! locomotory behavior +is_a: GO:0030534 ! adult behavior + +[Term] +id: GO:0008345 +name: larval locomotory behavior +namespace: biological_process +def: "Locomotory behavior in a larval (immature) organism." [GOC:ai] +comment: See also the biological process term 'locomotory behavior ; GO:0007626'. +synonym: "larval locomotory behaviour" EXACT [] +is_a: GO:0007626 ! locomotory behavior +is_a: GO:0030537 ! larval behavior + +[Term] +id: GO:0008346 +name: larval walking behavior +namespace: biological_process +def: "The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg." [GOC:go_curators, GOC:pr] +synonym: "larval walking behaviour" EXACT [] +is_a: GO:0008345 ! larval locomotory behavior +is_a: GO:0090659 ! walking behavior + +[Term] +id: GO:0008347 +name: glial cell migration +namespace: biological_process +alt_id: GO:0043359 +def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu] +synonym: "glia cell migration" EXACT [] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0042063 ! gliogenesis + +[Term] +id: GO:0008348 +name: negative regulation of antimicrobial humoral response +namespace: biological_process +alt_id: GO:0042154 +alt_id: GO:0042155 +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response." [GOC:go_curators] +synonym: "attenuation of antimicrobial humoral response" EXACT [] +synonym: "down regulation of antimicrobial humoral response" EXACT [] +synonym: "down-regulation of antimicrobial humoral response" EXACT [] +synonym: "downregulation of antimicrobial humoral response" EXACT [] +synonym: "inhibition of antimicrobial humoral response" NARROW [] +is_a: GO:0002759 ! regulation of antimicrobial humoral response +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0002921 ! negative regulation of humoral immune response +is_a: GO:0032102 ! negative regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019730 ! antimicrobial humoral response +relationship: negatively_regulates GO:0019730 ! antimicrobial humoral response + +[Term] +id: GO:0008349 +name: MAP kinase kinase kinase kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli." [GOC:bf, PMID:11790549] +synonym: "MAP4K activity" EXACT [PMID:20811974] +synonym: "MAPKKKK" EXACT [] +xref: Reactome:R-HSA-177692 "Activation of recruited TAK1 within the activated TLR3 complex" +xref: Reactome:R-HSA-936991 "Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3" +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: part_of GO:0000165 ! MAPK cascade +relationship: part_of GO:0000185 ! activation of MAPKKK activity + +[Term] +id: GO:0008350 +name: obsolete kinetochore motor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it includes cellular component information. +synonym: "kinetochore motor activity" EXACT [] +is_obsolete: true +consider: GO:0000776 +consider: GO:0003777 + +[Term] +id: GO:0008351 +name: obsolete microtubule severing activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a biological process. +synonym: "microtubule severing activity" EXACT [] +is_obsolete: true +consider: GO:0008017 +consider: GO:0051013 + +[Term] +id: GO:0008352 +name: katanin complex +namespace: cellular_component +def: "A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa)." [PMID:10910766] +comment: Consider also annotating to the molecular function term 'microtubule-severing ATPase activity ; GO:0008568'. +is_a: GO:0005875 ! microtubule associated complex +relationship: part_of GO:0005815 ! microtubule organizing center + +[Term] +id: GO:0008353 +name: RNA polymerase II CTD heptapeptide repeat kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats." [EC:2.7.11.23, GOC:mah] +synonym: "[RNA-polymerase]-subunit kinase activity" BROAD [] +synonym: "ATP:DNA-directed RNA polymerase phosphotransferase activity" BROAD [EC:2.7.11.23] +synonym: "CTD kinase activity" EXACT [EC:2.7.11.23] +synonym: "RNA polymerase II carboxy-terminal domain kinase activity" EXACT [] +synonym: "RNA polymerase subunit kinase activity" BROAD [EC:2.7.11.23] +synonym: "RNA-polymerase-subunit kinase activity" BROAD [EC:2.7.11.23] +synonym: "STK9" RELATED [EC:2.7.11.23] +xref: EC:2.7.11.23 +xref: MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN +xref: Reactome:R-HSA-167191 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex" +xref: Reactome:R-HSA-170704 "Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex" +xref: Reactome:R-HSA-170706 "Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex" +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0008354 +name: germ cell migration +namespace: biological_process +def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] +synonym: "germ-cell migration" EXACT [] +synonym: "primordial germ cell migration" RELATED [] +is_a: GO:0016477 ! cell migration +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007276 ! gamete generation + +[Term] +id: GO:0008355 +name: olfactory learning +namespace: biological_process +def: "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue." [ISBN:0582227089] +is_a: GO:0008306 ! associative learning +is_a: GO:0042048 ! olfactory behavior + +[Term] +id: GO:0008356 +name: asymmetric cell division +namespace: biological_process +def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] +synonym: "asymmetric cytokinesis" RELATED [] +synonym: "asymmetrical cell division" EXACT [] +synonym: "asymmetrical cytokinesis" RELATED [] +xref: Wikipedia:Asymmetric_cell_division +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0008358 +name: maternal determination of anterior/posterior axis, embryo +namespace: biological_process +def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +is_a: GO:0008595 ! anterior/posterior axis specification, embryo + +[Term] +id: GO:0008359 +name: regulation of bicoid mRNA localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location." [GOC:hb] +synonym: "regulation of bicoid mRNA localisation" EXACT [GOC:mah] +is_a: GO:0060281 ! regulation of oocyte development +is_a: GO:1902875 ! regulation of embryonic pattern specification +is_a: GO:1903429 ! regulation of cell maturation +is_a: GO:1904580 ! regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045450 ! bicoid mRNA localization +relationship: regulates GO:0045450 ! bicoid mRNA localization + +[Term] +id: GO:0008360 +name: regulation of cell shape +namespace: biological_process +alt_id: GO:0045788 +alt_id: GO:0045789 +def: "Any process that modulates the surface configuration of a cell." [GOC:dph, GOC:go_curators, GOC:tb] +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0008361 +name: regulation of cell size +namespace: biological_process +def: "Any process that modulates the size of a cell." [GOC:go_curators] +synonym: "cell size control" EXACT [] +is_a: GO:0032535 ! regulation of cellular component size + +[Term] +id: GO:0008362 +name: chitin-based embryonic cuticle biosynthetic process +namespace: biological_process +def: "Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12019232] +synonym: "embryonic cuticle anabolism" BROAD [] +synonym: "embryonic cuticle biosynthetic process" BROAD [] +synonym: "embryonic cuticle formation" BROAD [] +synonym: "embryonic cuticle synthesis" BROAD [] +is_a: GO:0040003 ! chitin-based cuticle development + +[Term] +id: GO:0008363 +name: larval chitin-based cuticle development +namespace: biological_process +def: "Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238] +synonym: "larval cuticle anabolism" BROAD [] +synonym: "larval cuticle biosynthetic process" BROAD [] +synonym: "larval cuticle formation" BROAD [] +synonym: "larval cuticle synthesis" BROAD [] +is_a: GO:0042337 ! cuticle development involved in chitin-based cuticle molting cycle +relationship: part_of GO:0002168 ! instar larval development + +[Term] +id: GO:0008364 +name: pupal chitin-based cuticle development +namespace: biological_process +def: "Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238] +synonym: "pupal cuticle anabolism" BROAD [] +synonym: "pupal cuticle formation" BROAD [] +synonym: "pupal cuticle synthesis" BROAD [] +is_a: GO:0042337 ! cuticle development involved in chitin-based cuticle molting cycle +relationship: part_of GO:0035209 ! pupal development + +[Term] +id: GO:0008365 +name: adult chitin-based cuticle development +namespace: biological_process +def: "Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238] +synonym: "adult chitin-based cuticle anabolism" EXACT [] +synonym: "adult chitin-based cuticle biosynthetic process" EXACT [] +synonym: "adult chitin-based cuticle formation" EXACT [] +synonym: "adult chitin-based cuticle synthesis" EXACT [] +synonym: "adult cuticle anabolism" BROAD [] +synonym: "adult cuticle biosynthetic process" BROAD [] +synonym: "adult cuticle formation" BROAD [] +synonym: "adult cuticle synthesis" BROAD [] +is_a: GO:0040003 ! chitin-based cuticle development + +[Term] +id: GO:0008366 +name: axon ensheathment +namespace: biological_process +alt_id: GO:0042553 +def: "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal." [GOC:jl, ISBN:0878932437] +synonym: "cellular axon ensheathment" EXACT [] +synonym: "cellular nerve ensheathment" RELATED [] +synonym: "nerve ensheathment" RELATED [] +is_a: GO:0007272 ! ensheathment of neurons + +[Term] +id: GO:0008369 +name: obsolete molecular function +namespace: molecular_function +def: "OBSOLETE. These are terms that have been removed from the active function ontology." [GOC:go_curators] +comment: This term was made obsolete because it is unnecessary in the OBO flat file format. +is_obsolete: true + +[Term] +id: GO:0008370 +name: obsolete cellular component +namespace: cellular_component +def: "OBSOLETE. These are terms that have been removed from the active component ontology." [GOC:go_curators] +comment: This term was made obsolete because it is unnecessary in the OBO flat file format. +is_obsolete: true + +[Term] +id: GO:0008371 +name: obsolete biological process +namespace: biological_process +def: "OBSOLETE. These are terms that have been removed from the active process ontology." [GOC:go_curators] +comment: This term was made obsolete because it is unnecessary in the OBO flat file format. +is_obsolete: true + +[Term] +id: GO:0008373 +name: sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins." [GOC:cjm, PMID:26192491, Wikipedia:Sialyltransferase] +xref: Reactome:R-HSA-981814 "GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position" +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups +relationship: part_of GO:0097503 ! sialylation + +[Term] +id: GO:0008374 +name: O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +xref: Reactome:R-HSA-1482775 "MLCL is acylated to CL by HADH (IM)" +xref: Reactome:R-HSA-1482781 "MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible)" +xref: Reactome:R-HSA-1482850 "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)" +xref: Reactome:R-HSA-1482861 "MLCL is acylated to CL by LCLAT1 (ER)" +xref: Reactome:R-HSA-1482867 "DLCL is acylated to MLCL by LCLAT1 (ER)" +xref: Reactome:R-HSA-162683 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH" +xref: Reactome:R-HSA-3238694 "PORCN palmitoleoylates N-glycosyl WNTs" +xref: Reactome:R-HSA-422017 "Ghrelin O-acyltransferase decanoylates Proghrelin" +xref: Reactome:R-HSA-422104 "Ghrelin O-acyltransferase octanoylates Proghrelin" +xref: Reactome:R-HSA-5358343 "HHAT palmitoylates Hh N-terminal fragment" +xref: Reactome:R-HSA-5483229 "HHAT G287V doesn't palmitoylate Hh-Np" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0008375 +name: acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar." [ISBN:0198506732] +synonym: "GlcNAc transferase activity" EXACT [] +xref: Reactome:R-HSA-5694487 "A4GNT transfers GlcNAc to core 2 mucins" +xref: Reactome:R-HSA-8879117 "POMGNT2 transfers GlcNAc to Man-DAG1" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008376 +name: acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide." [ISBN:0198506732] +synonym: "GalNAc transferase activity" EXACT [] +xref: Reactome:R-HSA-8855954 "B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD" +xref: Reactome:R-HSA-8931648 "B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1" +xref: Reactome:R-HSA-9605700 "B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008377 +name: light-induced release of internally sequestered calcium ion +namespace: biological_process +def: "The process in which the detection of light triggers the release of internally sequestered calcium ions." [GOC:ai] +synonym: "light-induced release of calcium from internal store" EXACT [] +synonym: "light-induced release of internally sequestered calcium ion (Ca2+)" EXACT [] +synonym: "light-induced release of internally stored calcium ion (Ca2+)" EXACT [] +is_a: GO:0051283 ! negative regulation of sequestering of calcium ion +relationship: part_of GO:0016056 ! rhodopsin mediated signaling pathway + +[Term] +id: GO:0008378 +name: galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [ISBN:0198506732] +xref: Reactome:R-HSA-1964501 "Addition of galactose to Core 6 glycoprotein" +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008379 +name: thioredoxin peroxidase activity +namespace: molecular_function +alt_id: GO:0009031 +def: "Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O." [MetaCyc:RXN0-267] +synonym: "thiol peroxidase activity" EXACT [] +synonym: "TPx activity" EXACT [] +synonym: "TrxPx activity" EXACT [] +xref: MetaCyc:RXN0-267 +xref: Reactome:R-HSA-2161612 "PGH2 is reduced to PGF2a by FAM213B" +xref: Reactome:R-HSA-3322995 "PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O" +xref: Reactome:R-HSA-3341343 "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O" +xref: Reactome:R-HSA-3697882 "PRDX5 reduces peroxynitrite to nitrite using TXN" +xref: Reactome:R-HSA-3697894 "PRDX5 reduces peroxynitrite to nitrite using TXN2" +is_a: GO:0004601 ! peroxidase activity +is_a: GO:0051920 ! peroxiredoxin activity + +[Term] +id: GO:0008380 +name: RNA splicing +namespace: biological_process +alt_id: GO:0006395 +def: "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." [GOC:krc, GOC:mah] +subset: goslim_yeast +synonym: "pre-mRNA splicing factor activity" RELATED [] +xref: Wikipedia:RNA_splicing +is_a: GO:0006396 ! RNA processing + +[Term] +id: GO:0008381 +name: mechanosensitive ion channel activity +namespace: molecular_function +alt_id: GO:0022833 +def: "Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress." [GOC:mtg_transport, ISBN:0815340729] +synonym: "mechanically gated channel activity" EXACT [] +synonym: "mechanically-gated channel activity" EXACT [] +synonym: "mechanically-gated ion channel activity" EXACT [] +xref: TC:1.A.23.2.1 +is_a: GO:0005216 ! ion channel activity +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0008384 +name: IkappaB kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein." [EC:2.7.11.10] +comment: Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB. +synonym: "ATP:IkappaB protein phosphotransferase activity" EXACT [EC:2.7.11.10] +synonym: "CHUK" RELATED [EC:2.7.11.10] +synonym: "ikappaB kinase activity" EXACT [EC:2.7.11.10] +synonym: "IKBKA" RELATED [EC:2.7.11.10] +synonym: "IKBKB" RELATED [EC:2.7.11.10] +synonym: "IKK" RELATED [EC:2.7.11.10] +synonym: "IKK-1" RELATED [EC:2.7.11.10] +synonym: "IKK-2" RELATED [EC:2.7.11.10] +synonym: "inhibitor of NF-kappaB kinase activity" EXACT [EC:2.7.11.10] +synonym: "inhibitor of NFkappaB kinase activity" EXACT [EC:2.7.11.10] +synonym: "STK12" RELATED [EC:2.7.11.10] +synonym: "TANK-binding kinase 1 activity" NARROW [EC:2.7.11.10] +synonym: "TBK1" RELATED [EC:2.7.11.10] +xref: EC:2.7.11.10 +xref: MetaCyc:2.7.11.10-RXN +xref: Reactome:R-HSA-5684267 "IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex" +xref: Reactome:R-HSA-5684275 "IKBKB phosphorylates TPL2 (MAP3K8) at Ser400" +is_a: GO:0004674 ! protein serine/threonine kinase activity +relationship: part_of GO:0007252 ! I-kappaB phosphorylation + +[Term] +id: GO:0008385 +name: IkappaB kinase complex +namespace: cellular_component +def: "A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:ma, PMID:12055104, PMID:20300203] +synonym: "heterotrimeric IKK complex" EXACT [GOC:bf] +synonym: "IKK complex" EXACT [] +synonym: "trimeric IKK complex" EXACT [PMID:21173796] +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0008386 +name: cholesterol monooxygenase (side-chain-cleaving) activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.6] +synonym: "C27-side chain cleavage enzyme" RELATED [EC:1.14.15.6] +synonym: "cholesterol 20-22-desmolase activity" EXACT [EC:1.14.15.6] +synonym: "cholesterol C(20-22) desmolase activity" EXACT [EC:1.14.15.6] +synonym: "cholesterol C20-22 desmolase activity" EXACT [EC:1.14.15.6] +synonym: "cholesterol desmolase activity" EXACT [EC:1.14.15.6] +synonym: "cholesterol side-chain cleavage enzyme activity" RELATED [EC:1.14.15.6] +synonym: "cholesterol side-chain-cleaving enzyme activity" RELATED [EC:1.14.15.6] +synonym: "cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)" EXACT [EC:1.14.15.6] +synonym: "Cyp11a1" NARROW [] +synonym: "cytochrome P-450(scc) activity" NARROW [EC:1.14.15.6] +synonym: "cytochrome P-450scc" RELATED [EC:1.14.15.6] +synonym: "cytochrome p450(scc) activity" NARROW [EC:1.14.15.6] +synonym: "cytochrome p450scc" RELATED [EC:1.14.15.6] +synonym: "desmolase, steroid 20-22" EXACT [EC:1.14.15.6] +synonym: "enzymes, cholesterol side-chain-cleaving" RELATED [EC:1.14.15.6] +synonym: "steroid 20-22 desmolase activity" BROAD [EC:1.14.15.6] +synonym: "steroid 20-22-lyase activity" BROAD [EC:1.14.15.6] +xref: EC:1.14.15.6 +xref: MetaCyc:1.14.15.6-RXN +xref: Reactome:R-HSA-193054 "Oxidation of cholesterol to 22beta-hydroxycholesterol" +xref: Reactome:R-HSA-193065 "Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol" +xref: Reactome:R-HSA-193101 "CYP11A1 cleaves 20a,22b-DHCHOL" +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0008387 +name: steroid 7-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O." [GOC:mah] +synonym: "cytochrome P450 CYP2A12" NARROW [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008388 +name: testosterone 15-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O." [GOC:ai] +synonym: "cytochrome P450 CYP2A4" NARROW [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008389 +name: coumarin 7-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+." [Reactome:163103] +synonym: "cytochrome P450 CYP2A5" NARROW [] +xref: Reactome:R-HSA-211881 "Coumarin is 7-hydroxylated by CYP2A13" +xref: Reactome:R-HSA-76453 "Coumarin is 7-hydroxylated by CYP2A6" +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008390 +name: testosterone 16-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O." [GOC:ai] +synonym: "cytochrome P450 CYP2B10" NARROW [] +synonym: "cytochrome P450 CYP2B9" NARROW [] +synonym: "cytochrome P450 CYP2D10" NARROW [] +synonym: "cytochrome P450 CYP2D11" NARROW [] +synonym: "cytochrome P450 CYP2D9" NARROW [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008391 +name: arachidonic acid monooxygenase activity +namespace: molecular_function +def: "Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water." [GOC:mah] +synonym: "cytochrome P450 CYP2B19" NARROW [] +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008392 +name: arachidonic acid epoxygenase activity +namespace: molecular_function +def: "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399] +synonym: "cytochrome P450 CYP2J5" NARROW [] +synonym: "cytochrome P450 CYP2J6" NARROW [] +xref: Reactome:R-HSA-211983 "CYP2J2 oxidises ARA" +is_a: GO:0008391 ! arachidonic acid monooxygenase activity + +[Term] +id: GO:0008395 +name: steroid hydroxylase activity +namespace: molecular_function +alt_id: GO:0008394 +def: "Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2." [ISBN:0721662544] +synonym: "cytochrome P450 CYP2G1" NARROW [] +synonym: "olfactory-specific steroid hydroxylase activity" NARROW [] +xref: Reactome:R-HSA-191983 "Cholesterol is hydroxylated to 25-hydroxycholesterol" +xref: Reactome:R-HSA-191999 "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol" +xref: Reactome:R-HSA-192042 "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al" +xref: Reactome:R-HSA-192054 "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)" +xref: Reactome:R-HSA-192123 "CYP27A1 27-hydroxylates CHOL" +xref: Reactome:R-HSA-193060 "CYP19A1 hydroxylates ANDST to E1" +xref: Reactome:R-HSA-193143 "CYP19A1 hydroxylates TEST to EST17b" +xref: Reactome:R-HSA-193393 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol" +xref: Reactome:R-HSA-193460 "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)" +xref: Reactome:R-HSA-193497 "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al" +xref: Reactome:R-HSA-193713 "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)" +xref: Reactome:R-HSA-193719 "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al" +xref: Reactome:R-HSA-193737 "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)" +xref: Reactome:R-HSA-193780 "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al" +xref: Reactome:R-HSA-193787 "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol" +xref: Reactome:R-HSA-193792 "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol" +xref: Reactome:R-HSA-193965 "CYP11B2 oxidises 18HCORST to ALDO" +xref: Reactome:R-HSA-193995 "CYP11B2 18-hydroxylates CORST to 18HCORST" +xref: Reactome:R-HSA-5601849 "Defective CYP19A1 does not convert ANDST to E1" +xref: Reactome:R-HSA-5602170 "CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol" +xref: Reactome:R-HSA-6785244 "Defective CYP11B2 does not oxidise 18HCORST" +xref: Reactome:R-HSA-6785245 "Defective CYP11B2 does not oxidise CORST" +xref: Reactome:R-HSA-9035960 "Defective CYP27A1 does not 27-hydroxylate 5-CHOL3,7,24(s)-triol" +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0008396 +name: oxysterol 7-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O." [PMID:10882791] +synonym: "cytochrome P450 CYP7B1" NARROW [] +xref: Reactome:R-HSA-191972 "27-hydroxycholesterol is 7alpha-hydroxylated" +xref: Reactome:R-HSA-192065 "CYP7B1 7-hydroxylates 25OH-CHOL" +xref: Reactome:R-HSA-192178 "CYP39A1 7-hydroxylates 24OH-CHOL" +xref: Reactome:R-HSA-5602885 "Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL" +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008397 +name: sterol 12-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O." [GOC:mah] +synonym: "cytochrome P450 CYP8B1" NARROW [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008398 +name: sterol 14-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O." [EC:1.14.13.70] +synonym: "cytochrome P450 51 activity" NARROW [EC:1.14.13.70] +synonym: "cytochrome P450 CYP51" NARROW [] +synonym: "lanosterol 14-alpha-demethylase activity" NARROW [EC:1.14.13.70] +synonym: "lanosterol 14-demethylase activity" NARROW [EC:1.14.13.70] +synonym: "lanosterol 14alpha-demethylase activity" EXACT [EC:1.14.13.70] +synonym: "obtusufoliol 14-demethylase activity" NARROW [EC:1.14.13.70] +synonym: "sterol 14-alpha-demethylase activity" EXACT [EC:1.14.13.70] +synonym: "sterol 14alpha-demethylase activity" EXACT [EC:1.14.13.70] +synonym: "sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)" EXACT [EC:1.14.13.70] +xref: EC:1.14.13.70 +xref: MetaCyc:1.14.13.70-RXN +xref: Reactome:R-HSA-194678 "CYP51A1 demethylates LNSOL" +xref: RHEA:14917 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +is_a: GO:0032451 ! demethylase activity + +[Term] +id: GO:0008399 +name: naphthalene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide." [PMID:1742282, PMID:1981702] +synonym: "cytochrome P450 CYP2F2" NARROW [] +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008401 +name: retinoic acid 4-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid." [PMID:19519282, PMID:9250660] +synonym: "cytochrome P450 CYP261" NARROW [] +xref: Reactome:R-HSA-211874 "CYP2S1 4-hydroxylates atRA" +xref: Reactome:R-HSA-211923 "CYP26C1 4-hydroxylates 9cRA" +xref: Reactome:R-HSA-212007 "CYP26A1,B1 4-hydroxylate atRA" +xref: Reactome:R-HSA-5362525 "CYP26A1,B1,C1 4-hydroxylate atRA" +xref: Reactome:R-HSA-5602050 "Defective CYP26C1 does not 4-hydroxylate 9cRA" +xref: Reactome:R-HSA-5602063 "Defective CYP26B1 does not 4-hydroxylate atRA" +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008403 +name: 25-hydroxycholecalciferol-24-hydroxylase activity +namespace: molecular_function +alt_id: GO:0030344 +def: "Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol." [ISBN:0471331309] +synonym: "25-hydroxyvitamin D3 24-hydroxylase activity" EXACT [] +synonym: "cytochrome P450 CYP24" NARROW [] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0070576 ! vitamin D 24-hydroxylase activity + +[Term] +id: GO:0008404 +name: arachidonic acid 14,15-epoxygenase activity +namespace: molecular_function +def: "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399] +synonym: "cytochrome P450 CYP2C29" NARROW [] +synonym: "cytochrome P450 CYP2C39" NARROW [] +is_a: GO:0008392 ! arachidonic acid epoxygenase activity + +[Term] +id: GO:0008405 +name: arachidonic acid 11,12-epoxygenase activity +namespace: molecular_function +def: "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid." [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399] +synonym: "cytochrome P450 CYP2C38" NARROW [] +is_a: GO:0008392 ! arachidonic acid epoxygenase activity + +[Term] +id: GO:0008406 +name: gonad development +namespace: biological_process +def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732] +synonym: "gonadogenesis" EXACT [GOC:cjm] +is_a: GO:0048513 ! animal organ development +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0045137 ! development of primary sexual characteristics + +[Term] +id: GO:0008407 +name: chaeta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell." [FBbt:00005177, GOC:bf, GOC:cjm, GOC:dos, GOC:go_curators] +synonym: "bristle morphogenesis" NARROW [GOC:bf, GOC:dos] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0022416 ! chaeta development + +[Term] +id: GO:0008408 +name: 3'-5' exonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end." [GOC:ai] +synonym: "3'-5'-exonuclease activity" EXACT [] +xref: Reactome:R-HSA-3245943 "Viral DNA cleavage by TREX1" +is_a: GO:0004527 ! exonuclease activity + +[Term] +id: GO:0008409 +name: 5'-3' exonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end." [GOC:ai] +xref: Reactome:R-HSA-5358599 "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch" +xref: Reactome:R-HSA-5358619 "EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL)" +is_a: GO:0004527 ! exonuclease activity + +[Term] +id: GO:0008410 +name: CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)." [GOC:jl] +xref: EC:2.8.3 +xref: Reactome:R-HSA-70713 "BCKDH transfers CoA group from CoA-SH to BCAAs" +is_a: GO:0016782 ! transferase activity, transferring sulfur-containing groups + +[Term] +id: GO:0008411 +name: 4-hydroxybutyrate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate." [GOC:jl] +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0008412 +name: 4-hydroxybenzoate octaprenyltransferase activity +namespace: molecular_function +alt_id: GO:0000043 +alt_id: GO:0048043 +alt_id: GO:0048044 +def: "Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate." [MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN] +synonym: "4-HB polyprenyltransferase activity" EXACT [] +synonym: "para-hydroxybenzoate transferase activity" EXACT [] +synonym: "para-hydroxybenzoate-polyprenyl diphosphate transferase activity" EXACT [] +synonym: "para-hydroxybenzoate:polyprenyltransferase activity" EXACT [] +synonym: "PHB polyprenyl diphosphate transferase activity" EXACT [] +xref: EC:2.5.1 +xref: MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN +is_a: GO:0002094 ! polyprenyltransferase activity + +[Term] +id: GO:0008413 +name: 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription." [PMID:15878881] +synonym: "7,8-dihydro-8-oxoguanine-triphosphatase activity" EXACT [] +synonym: "8-oxo-7,8-dihydroguanine triphosphatase activity" EXACT [] +synonym: "8-oxo-7,8-dihydroguanosine triphosphatase activity" EXACT [] +synonym: "8-oxo-GTPase activity" EXACT [] +xref: EC:3.6.1 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity + +[Term] +id: GO:0008414 +name: CDP-alcohol phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a CDP-alcohol group from one compound to another." [GOC:jl] +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0008417 +name: fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] +xref: Reactome:R-HSA-9033949 "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC" +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups +relationship: part_of GO:0036065 ! fucosylation + +[Term] +id: GO:0008418 +name: protein-N-terminal asparagine amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein." [PMID:8910481] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008419 +name: RNA lariat debranching enzyme activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide." [PMID:7519612] +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008420 +name: RNA polymerase II CTD heptapeptide repeat phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate." [PMID:22622228] +synonym: "CTD phosphatase activity" EXACT [] +synonym: "RNA polymerase II carboxy-terminal domain phosphatase activity" EXACT [] +is_a: GO:0004722 ! protein serine/threonine phosphatase activity + +[Term] +id: GO:0008421 +name: long-chain fatty-acyl-glutamate deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate." [EC:3.5.1.55] +synonym: "long-chain acylglutamate amidase activity" EXACT [EC:3.5.1.55] +synonym: "long-chain aminoacylase activity" EXACT [EC:3.5.1.55] +synonym: "long-chain fatty acyl-glutamate deacylase activity" EXACT [GOC:mah] +synonym: "long-chain-fatty-acyl-glutamate deacylase activity" EXACT [] +synonym: "N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.55] +xref: EC:3.5.1.55 +xref: MetaCyc:3.5.1.55-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008422 +name: beta-glucosidase activity +namespace: molecular_function +alt_id: GO:0016983 +def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose." [EC:3.2.1.21] +synonym: "amygdalase activity" NARROW [EC:3.2.1.21] +synonym: "amygdalinase" BROAD [EC:3.2.1.21] +synonym: "arbutinase activity" EXACT [EC:3.2.1.21] +synonym: "aryl-beta-glucosidase activity" EXACT [EC:3.2.1.21] +synonym: "beta-1,6-glucosidase activity" EXACT [EC:3.2.1.21] +synonym: "beta-D-glucosidase activity" EXACT [EC:3.2.1.21] +synonym: "beta-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.21] +synonym: "beta-glucoside glucohydrolase activity" EXACT [EC:3.2.1.21] +synonym: "cellobiase activity" NARROW [EC:3.2.1.21] +synonym: "cytokine beta-glucosidase activity" NARROW [] +synonym: "elaterase activity" NARROW [EC:3.2.1.21] +synonym: "emulsin" RELATED [EC:3.2.1.21] +synonym: "gentiobiase activity" NARROW [EC:3.2.1.21] +synonym: "gentobiase activity" NARROW [EC:3.2.1.21] +synonym: "limarase activity" NARROW [EC:3.2.1.21] +synonym: "p-nitrophenyl beta-glucosidase activity" EXACT [EC:3.2.1.21] +synonym: "primeverosidase activity" NARROW [EC:3.2.1.21] +synonym: "salicilinase activity" NARROW [EC:3.2.1.21] +xref: EC:3.2.1.21 +xref: MetaCyc:3.2.1.21-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0008423 +name: obsolete bleomycin hydrolase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred." [EC:3.4.22.40] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminopeptidase C (Lactococcus lactis)" NARROW [EC:3.4.22.40] +synonym: "bleomycin hydrolase activity" EXACT [] +xref: EC:3.4.22.40 +xref: MetaCyc:3.4.22.40-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0008424 +name: glycoprotein 6-alpha-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+)." [EC:2.4.1.68, RHEA:12985] +synonym: "FucT" RELATED [EC:2.4.1.68] +synonym: "GDP-fucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDP-L-fucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "GDPfucose-glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] +synonym: "glycoprotein fucosyltransferase activity" BROAD [EC:2.4.1.68] +synonym: "guanosine diphosphofucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] +xref: EC:2.4.1.68 +xref: KEGG_REACTION:R05988 +xref: MetaCyc:2.4.1.68-RXN +xref: Reactome:R-HSA-1028788 "FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP" +xref: RHEA:12985 +is_a: GO:0046921 ! alpha-(1->6)-fucosyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein +relationship: part_of GO:0036071 ! N-glycan fucosylation + +[Term] +id: GO:0008425 +name: 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9083048] +synonym: "2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] +synonym: "coenzyme Q biosynthesis methyltransferase activity" EXACT [] +synonym: "coenzyme Q biosynthetic process methyltransferase activity" EXACT [] +synonym: "ubiquinone biosynthesis methyltransferase activity" BROAD [] +synonym: "ubiquinone biosynthetic process methyltransferase activity" BROAD [] +xref: EC:2.1.1 +is_a: GO:0030580 ! quinone cofactor methyltransferase activity + +[Term] +id: GO:0008426 +name: protein kinase C inhibitor activity +namespace: molecular_function +alt_id: GO:0004863 +def: "Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein." [GOC:ai] +synonym: "diacylglycerol-activated phospholipid-dependent PKC inhibitor activity" EXACT [] +synonym: "diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity" EXACT [] +synonym: "PKC inhibitor activity" EXACT [] +is_a: GO:0030291 ! protein serine/threonine kinase inhibitor activity + +[Term] +id: GO:0008427 +name: calcium-dependent protein kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a calcium-dependent protein kinase." [GOC:mah] +is_a: GO:0004860 ! protein kinase inhibitor activity +is_a: GO:0010858 ! calcium-dependent protein kinase regulator activity + +[Term] +id: GO:0008428 +name: ribonuclease inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:ai] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0008429 +name: phosphatidylethanolamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732] +is_a: GO:0005543 ! phospholipid binding + +[Term] +id: GO:0008430 +name: selenium binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with selenium (Se)." [GOC:ai] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0008431 +name: vitamin E binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant." [ISBN:0721662544] +synonym: "alpha-tocopherol binding" NARROW [] +synonym: "tocopherol binding" EXACT [] +is_a: GO:0019842 ! vitamin binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0008432 +name: JUN kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family." [GOC:jl] +synonym: "JNK binding" EXACT [GOC:BHF, GOC:ebc] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0008435 +name: obsolete anticoagulant activity +namespace: molecular_function +def: "OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation." [ISBN:0198506732] +comment: This term was made obsolete because it represents a biological process. +synonym: "anticoagulant activity" EXACT [] +is_obsolete: true +replaced_by: GO:0050819 + +[Term] +id: GO:0008436 +name: obsolete heterogeneous nuclear ribonucleoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a cellular component rather than a molecular function. +synonym: "heterogeneous nuclear ribonucleoprotein" EXACT [] +synonym: "hnRNP" EXACT [] +is_obsolete: true +replaced_by: GO:1990904 + +[Term] +id: GO:0008437 +name: thyrotropin-releasing hormone activity +namespace: molecular_function +def: "The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary." [ISBN:0198506732] +synonym: "thyrotropin releasing hormone activity" EXACT [] +synonym: "TRH activity" EXACT [ISBN:0198506732] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0008438 +name: obsolete 1-phosphatidylinositol-5-phosphate kinase +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide." [EC:2.7.1.143] +comment: This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref. +synonym: "1-phosphatidylinositol-5-phosphate kinase" EXACT [] +is_obsolete: true +consider: GO:0016309 + +[Term] +id: GO:0008439 +name: obsolete monophenol monooxygenase activator activity +namespace: molecular_function +def: "OBSOLETE. Increases the activity of the enzyme monophenol monooxygenase." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "monophenol monooxygenase activator activity" EXACT [] +synonym: "prophenol oxidase activator" RELATED [] +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008440 +name: inositol-1,4,5-trisphosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.127, RHEA:11020] +synonym: "1D-myo-inositol-trisphosphate 3-kinase activity" EXACT [] +synonym: "ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.127] +synonym: "inositol trisphosphate 3-kinase activity" EXACT [] +synonym: "inositol-trisphosphate 3-kinase activity" EXACT [] +synonym: "ins(1,4,5)P(3) 3-kinase activity" EXACT [EC:2.7.1.127] +synonym: "Ins(1,4,5)P3 3-kinase activity" EXACT [EC:2.7.1.127] +synonym: "IP3 3-kinase activity" NARROW [EC:2.7.1.127] +synonym: "IP3K activity" NARROW [EC:2.7.1.127] +xref: EC:2.7.1.127 +xref: KEGG_REACTION:R03433 +xref: MetaCyc:2.7.1.127-RXN +xref: Reactome:R-HSA-1855153 "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol" +xref: Reactome:R-HSA-1855233 "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus" +xref: RHEA:11020 +is_a: GO:0051766 ! inositol trisphosphate kinase activity + +[Term] +id: GO:0008441 +name: 3'(2'),5'-bisphosphate nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate." [EC:3.1.3.7] +synonym: "3'(2'),5' bisphosphate nucleotidase activity" EXACT [] +synonym: "3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity" EXACT [EC:3.1.3.7] +synonym: "3'-phosphoadenylylsulfate 3'-phosphatase activity" EXACT [EC:3.1.3.7] +synonym: "adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity" EXACT [EC:3.1.3.7] +synonym: "DPNPase activity" EXACT [EC:3.1.3.7] +synonym: "phosphoadenylate 3'-nucleotidase activity" EXACT [EC:3.1.3.7] +xref: EC:3.1.3.7 +xref: MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN +xref: Reactome:R-HSA-176606 "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate" +xref: Reactome:R-HSA-8953499 "IMPAD1 hydrolyses PAP to AMP" +xref: RHEA:10040 +is_a: GO:0008252 ! nucleotidase activity + +[Term] +id: GO:0008442 +name: 3-hydroxyisobutyrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+." [EC:1.1.1.31] +xref: EC:1.1.1.31 +xref: MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-508473 "methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+" +xref: Reactome:R-HSA-70885 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+" +xref: RHEA:17681 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008443 +name: phosphofructokinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule." [GOC:jl] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008444 +name: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+)." [EC:2.7.8.5, RHEA:12593] +synonym: "3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity" EXACT [EC:2.7.8.5] +synonym: "CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "glycerol 3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "glycerol phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "glycerophosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +synonym: "PGP synthase activity" EXACT [EC:2.7.8.5] +synonym: "phosphatidylglycerol phosphate synthase activity" EXACT [EC:2.7.8.5] +synonym: "phosphatidylglycerol phosphate synthetase activity" EXACT [EC:2.7.8.5] +synonym: "phosphatidylglycerolphosphate synthase activity" EXACT [EC:2.7.8.5] +synonym: "phosphatidylglycerophosphate synthase activity" EXACT [EC:2.7.8.5] +synonym: "phosphatidylglycerophosphate synthetase activity" EXACT [EC:2.7.8.5] +synonym: "sn-glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] +xref: EC:2.7.8.5 +xref: KEGG_REACTION:R01801 +xref: MetaCyc:PHOSPHAGLYPSYN-RXN +xref: Reactome:R-HSA-1482939 "CDP-DAG is converted to PGP by PGS1" +xref: RHEA:12593 +is_a: GO:0017169 ! CDP-alcohol phosphatidyltransferase activity + +[Term] +id: GO:0008445 +name: D-aspartate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide." [EC:1.4.3.1] +synonym: "aspartic oxidase activity" EXACT [EC:1.4.3.1] +synonym: "D-aspartate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.1] +synonym: "D-aspartic oxidase activity" EXACT [EC:1.4.3.1] +xref: EC:1.4.3.1 +xref: MetaCyc:D-ASPARTATE-OXIDASE-RXN +xref: Reactome:R-HSA-6810076 "DDO oxidizes D-Asp to OA" +xref: RHEA:12512 +is_a: GO:0003884 ! D-amino-acid oxidase activity +is_a: GO:0015922 ! aspartate oxidase activity + +[Term] +id: GO:0008446 +name: GDP-mannose 4,6-dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O." [EC:4.2.1.47, RHEA:23820] +synonym: "GDP-D-mannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] +synonym: "GDP-D-mannose dehydratase activity" EXACT [EC:4.2.1.47] +synonym: "GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)" EXACT [EC:4.2.1.47] +synonym: "GDP-mannose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.47] +synonym: "GDPmannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] +synonym: "Gmd" RELATED [EC:4.2.1.47] +synonym: "guanosine 5'-diphosphate-D-mannose oxidoreductase activity" EXACT [EC:4.2.1.47] +synonym: "guanosine diphosphomannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] +synonym: "guanosine diphosphomannose oxidoreductase activity" EXACT [EC:4.2.1.47] +xref: EC:4.2.1.47 +xref: KEGG_REACTION:R00888 +xref: MetaCyc:GDPMANDEHYDRA-RXN +xref: Reactome:R-HSA-6787632 "GMDS dehydrates GDP-Man to GDP-DHDMan" +xref: RHEA:23820 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008447 +name: L-ascorbate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O." [EC:1.10.3.3] +synonym: "AA oxidase activity" EXACT [EC:1.10.3.3] +synonym: "AAO" RELATED [EC:1.10.3.3] +synonym: "ascorbase activity" EXACT [EC:1.10.3.3] +synonym: "ascorbate dehydrogenase activity" EXACT [EC:1.10.3.3] +synonym: "ascorbate oxidase activity" EXACT [EC:1.10.3.3] +synonym: "ascorbic acid oxidase activity" EXACT [EC:1.10.3.3] +synonym: "ascorbic oxidase activity" EXACT [EC:1.10.3.3] +synonym: "L-ascorbate:O2 oxidoreductase activity" EXACT [EC:1.10.3.3] +synonym: "L-ascorbate:oxygen oxidoreductase activity" EXACT [EC:1.10.3.3] +synonym: "L-ascorbic acid oxidase activity" EXACT [EC:1.10.3.3] +xref: EC:1.10.3.3 +xref: MetaCyc:L-ASCORBATE-OXIDASE-RXN +xref: RHEA:30243 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0008448 +name: N-acetylglucosamine-6-phosphate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate." [EC:3.5.1.25] +synonym: "2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity" EXACT [EC:3.5.1.25] +synonym: "acetylaminodeoxyglucosephosphate acetylhydrolase activity" EXACT [EC:3.5.1.25] +synonym: "acetylglucosamine phosphate deacetylase activity" EXACT [EC:3.5.1.25] +synonym: "N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity" EXACT [EC:3.5.1.25] +xref: EC:3.5.1.25 +xref: MetaCyc:NAG6PDEACET-RXN +xref: Reactome:R-HSA-6803789 "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA" +xref: RHEA:22936 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0008449 +name: N-acetylglucosamine-6-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate." [EC:3.1.6.14] +synonym: "2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity" EXACT [EC:3.1.6.14] +synonym: "acetylglucosamine 6-sulfatase activity" EXACT [EC:3.1.6.14] +synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.14] +synonym: "glucosamine-6-sulfatase activity" EXACT [EC:3.1.6.14] +synonym: "N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity" EXACT [EC:3.1.6.14] +synonym: "N-acetylglucosamine 6-sulfate sulfatase activity" EXACT [EC:3.1.6.14] +synonym: "N-acetylglucosamine-6-sulphatase activity" EXACT [] +synonym: "O,N-disulfate O-sulfohydrolase activity" EXACT [EC:3.1.6.14] +xref: EC:3.1.6.14 +xref: MetaCyc:3.1.6.14-RXN +xref: Reactome:R-HSA-1638032 "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate" +xref: Reactome:R-HSA-2263495 "Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S" +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0008450 +name: obsolete O-sialoglycoprotein endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated." [EC:3.4.24.57] +comment: This term was made obsolete because it represents a gene product. +synonym: "glycophorin A proteinase activity" EXACT [EC:3.4.24.57] +synonym: "glycoprotease activity" RELATED [EC:3.4.24.57] +synonym: "glycoproteinase activity" EXACT [EC:3.4.24.57] +synonym: "O-sialoglycoprotein endopeptidase activity" EXACT [] +synonym: "sialoglycoprotease activity" EXACT [EC:3.4.24.57] +synonym: "sialoglycoproteinase activity" EXACT [EC:3.4.24.57] +xref: EC:3.4.24.57 +xref: MetaCyc:3.4.24.57-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008451 +name: obsolete X-Pro aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide." [EC:3.4.11.9] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminoacylproline aminopeptidase activity" EXACT [EC:3.4.11.9] +synonym: "aminopeptidase P" EXACT [] +synonym: "proline aminopeptidase" BROAD [EC:3.4.11.9] +synonym: "X-Pro aminopeptidase activity" EXACT [] +synonym: "Xaa-Pro aminopeptidase activity" EXACT [] +xref: EC:3.4.11.9 +xref: MetaCyc:3.4.11.9-RXN +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0008452 +name: RNA ligase activity +namespace: molecular_function +def: "Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another." [GOC:mah] +is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0008453 +name: alanine-glyoxylate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine." [EC:2.6.1.44] +synonym: "AGT activity" EXACT [EC:2.6.1.44] +synonym: "alanine--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.44] +synonym: "alanine-glyoxylate aminotransferase activity" EXACT [] +synonym: "alanine-glyoxylic aminotransferase activity" EXACT [EC:2.6.1.44] +synonym: "L-alanine-glycine transaminase activity" EXACT [EC:2.6.1.44] +synonym: "L-alanine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.44] +xref: EC:2.6.1.44 +xref: MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-389684 "glyoxylate + alanine => glycine + pyruvate [peroxisome]" +xref: Reactome:R-HSA-904864 "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate" +xref: RHEA:24248 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0008454 +name: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R." [EC:2.4.1.145] +synonym: "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.145] +synonym: "alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "beta-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] +synonym: "GnTIV activity" EXACT [EC:2.4.1.145] +synonym: "N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] +synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] +synonym: "UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.145] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV" RELATED [EC:2.4.1.145] +xref: EC:2.4.1.145 +xref: MetaCyc:2.4.1.145-RXN +xref: Reactome:R-HSA-975903 "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV" +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0008455 +name: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R." [EC:2.4.1.143] +synonym: "acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] +synonym: "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "GnTII activity" EXACT [EC:2.4.1.143] +synonym: "N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] +synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] +synonym: "UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +synonym: "uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] +xref: EC:2.4.1.143 +xref: MetaCyc:2.4.1.143-RXN +xref: Reactome:R-HSA-4793955 "Defective MGAT2 does not transfer GlcNAc to N-glycans" +xref: Reactome:R-HSA-975829 "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2" +xref: RHEA:12941 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0008456 +name: alpha-N-acetylgalactosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides." [EC:3.2.1.49] +synonym: "alpha-acetylgalactosaminidase activity" EXACT [EC:3.2.1.49] +synonym: "alpha-galactosidase B activity" RELATED [EC:3.2.1.49] +synonym: "alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity" EXACT [EC:3.2.1.49] +synonym: "alpha-NAGA activity" EXACT [EC:3.2.1.49] +synonym: "N-acetyl-alpha-D-galactosaminidase activity" EXACT [EC:3.2.1.49] +synonym: "N-acetyl-alpha-galactosaminidase activity" EXACT [EC:3.2.1.49] +xref: EC:3.2.1.49 +xref: MetaCyc:3.2.1.49-RXN +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0008457 +name: beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide." [EC:2.4.1.149] +synonym: "poly-N-acetyllactosamine extension enzyme activity" BROAD [] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity" EXACT [] +synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.163] +xref: EC:2.4.1.149 +xref: MetaCyc:2.4.1.163-RXN +xref: RHEA:23004 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0008458 +name: carnitine O-octanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA." [EC:2.3.1.137, RHEA:17177] +synonym: "carnitine medium-chain acyltransferase activity" EXACT [EC:2.3.1.137] +synonym: "easily solubilized mitochondrial carnitine palmitoyltransferase" NARROW [EC:2.3.1.137] +synonym: "medium-chain/long-chain carnitine acyltransferase activity" EXACT [EC:2.3.1.137] +synonym: "octanoyl-CoA:L-carnitine O-octanoyltransferase activity" EXACT [EC:2.3.1.137] +synonym: "overt mitochondrial carnitine palmitoyltransferase" NARROW [EC:2.3.1.137] +xref: EC:2.3.1.137 +xref: KEGG_REACTION:R03779 +xref: MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN +xref: Reactome:R-HSA-390281 "4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH" +xref: RHEA:17177 +is_a: GO:0016406 ! carnitine O-acyltransferase activity +is_a: GO:0016414 ! O-octanoyltransferase activity + +[Term] +id: GO:0008459 +name: chondroitin 6-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate." [EC:2.8.2.17] +synonym: "3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity" EXACT [EC:2.8.2.17] +synonym: "3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity" EXACT [EC:2.8.2.17] +synonym: "chondroitin 6-O-sulfotransferase activity" EXACT [EC:2.8.2.17] +synonym: "chondroitin 6-sulphotransferase activity" EXACT [] +synonym: "terminal 6-sulfotransferase activity" EXACT [EC:2.8.2.17] +xref: EC:2.8.2.17 +xref: MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-2018682 "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains" +xref: Reactome:R-HSA-3595175 "Defective CHST3 does not transfer SO4(2-) to chondroitin" +xref: RHEA:11108 +is_a: GO:0034481 ! chondroitin sulfotransferase activity + +[Term] +id: GO:0008460 +name: dTDP-glucose 4,6-dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O." [EC:4.2.1.46, RHEA:17221] +synonym: "dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.46] +synonym: "dTDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.46] +synonym: "dTDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.46] +synonym: "dTDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.46] +synonym: "TDP-glucose oxidoreductase activity" EXACT [EC:4.2.1.46] +synonym: "thymidine diphosphoglucose oxidoreductase activity" EXACT [EC:4.2.1.46] +xref: EC:4.2.1.46 +xref: KEGG_REACTION:R06513 +xref: MetaCyc:DTDPGLUCDEHYDRAT-RXN +xref: RHEA:17221 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008462 +name: obsolete endopeptidase Clp activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs)." [EC:3.4.21.92] +comment: This term was made obsolete because it represents a gene product. +synonym: "ATP-dependent Clp protease" NARROW [EC:3.4.21.92] +synonym: "caseinolytic protease activity" RELATED [EC:3.4.21.92] +synonym: "Clp protease" NARROW [EC:3.4.21.92] +synonym: "ClpP" RELATED [EC:3.4.21.92] +synonym: "endopeptidase Clp activity" EXACT [] +synonym: "endopeptidase Ti activity" RELATED [EC:3.4.21.92] +synonym: "protease Ti activity" RELATED [EC:3.4.21.92] +xref: EC:3.4.21.92 +xref: MetaCyc:3.4.21.92-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008463 +name: formylmethionine deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate." [EC:3.5.1.31, RHEA:17781] +synonym: "N-formyl-L-methionine amidohydrolase activity" EXACT [EC:3.5.1.31] +xref: EC:3.5.1.31 +xref: KEGG_REACTION:R00653 +xref: MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN +xref: RHEA:17781 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008464 +name: obsolete gamma-glutamyl hydrolase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid." [EC:3.4.19.9] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase G activity" BROAD [EC:3.4.19.9] +synonym: "conjugase activity" RELATED [EC:3.4.19.9] +synonym: "folate conjugase activity" RELATED [EC:3.4.19.9] +synonym: "folic acid conjugase activity" EXACT [EC:3.4.19.9] +synonym: "gamma-Glu-X carboxypeptidase activity" EXACT [EC:3.4.19.9] +synonym: "gamma-glutamyl hydrolase activity" EXACT [] +synonym: "lysosomal gamma-glutamyl carboxypeptidase activity" NARROW [EC:3.4.19.9] +synonym: "poly(gamma-glutamic acid) endohydrolase activity" EXACT [EC:3.4.19.9] +synonym: "poly(glutamic acid) hydrolase II" RELATED [EC:3.4.19.9] +synonym: "polyglutamate hydrolase activity" EXACT [EC:3.4.19.9] +synonym: "pteroyl-poly-alpha-glutamate hydrolase activity" NARROW [EC:3.4.19.9] +synonym: "pteroyl-poly-gamma-glutamate hydrolase activity" EXACT [EC:3.4.19.9] +synonym: "pteroylpoly-gamma-glutamyl hydrolase activity" EXACT [EC:3.4.19.9] +xref: EC:3.4.19.9 +xref: MetaCyc:3.4.19.9-RXN +is_obsolete: true +replaced_by: GO:0008242 + +[Term] +id: GO:0008465 +name: glycerate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+." [EC:1.1.1.29] +synonym: "hydroxypyruvate dehydrogenase activity" BROAD [EC:1.1.1.29] +xref: EC:1.1.1.29 +xref: MetaCyc:GLYCERATE-DEHYDROGENASE-RXN +xref: RHEA:17905 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008466 +name: glycogenin glucosyltransferase activity +namespace: molecular_function +alt_id: GO:0047210 +def: "Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin." [EC:2.4.1.186] +synonym: "1,4alpha-glucan-protein synthase (UDP-forming) activity" EXACT [] +synonym: "alpha-1,4-glucan-protein synthase (UDP-forming) activity" EXACT [] +synonym: "glycogenin activity" RELATED [EC:2.4.1.186] +synonym: "priming glucosyltransferase activity" RELATED [EC:2.4.1.186] +synonym: "UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.186] +synonym: "UDP-glucose:glycogenin glucosyltransferase activity" EXACT [EC:2.4.1.186] +xref: EC:2.4.1.186 +xref: MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-3322003 "Autoglucosylation of GYG1 complexed with GYS1-b" +xref: Reactome:R-HSA-3322014 "Autoglucosylation of GYG2 complexed with GYS2-a" +xref: Reactome:R-HSA-3322019 "Autoglucosylation of GYG2 complexed with GYS2-b" +xref: Reactome:R-HSA-3322025 "Autoglucosylation of GYG1 complexed with GYS1-a" +xref: Reactome:R-HSA-3814838 "Defective GYG1 is not autoglucosyolated" +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0008467 +name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S." [EC:2.8.2.23] +synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase" BROAD [EC:2.8.2.23] +synonym: "3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] +synonym: "3-OST-1 activity" EXACT [EC:2.8.2.23] +synonym: "glucosaminyl 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] +synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] +synonym: "heparin-glucosamine 3-O-sulfotransferase activity" RELATED [] +synonym: "heparin-glucosamine 3-O-sulphotransferase activity" RELATED [] +synonym: "isoform/isozyme 1 (3-OST-1, HS3ST1)" RELATED [EC:2.8.2.23] +xref: EC:2.8.2.23 +xref: MetaCyc:2.8.2.23-RXN +xref: Reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate" +xref: Reactome:R-HSA-2076611 "HS3STs sulfate GlcN at C3 in heparan sulfate" +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0008469 +name: histone-arginine N-methyltransferase activity +namespace: molecular_function +alt_id: GO:0016276 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine." [PMID:8002954] +synonym: "histone methyltransferase activity" BROAD [] +synonym: "histone protein methylase activity" EXACT [] +synonym: "histone protein methylase I" RELATED [] +synonym: "histone-arginine N-methylase activity" EXACT [GOC:mah] +synonym: "nuclear protein (histone) N-methyltransferase activity" EXACT [] +synonym: "protein methylase I activity" BROAD [] +synonym: "S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity" EXACT [] +xref: Reactome:R-HSA-5205799 "CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)" +xref: Reactome:R-HSA-5205861 "COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3)" +xref: Reactome:R-HSA-5216234 "PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3)" +xref: Reactome:R-HSA-5661117 "CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3" +xref: Reactome:R-HSA-8936584 "PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter" +xref: Reactome:R-HSA-8936608 "PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter" +xref: Reactome:R-HSA-8937022 "PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter" +xref: Reactome:R-HSA-8937113 "PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter" +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity +is_a: GO:0042054 ! histone methyltransferase activity +relationship: part_of GO:0034969 ! histone arginine methylation + +[Term] +id: GO:0008470 +name: isovaleryl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF." [EC:1.3.8.4] +synonym: "3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.8.4] +synonym: "3-methylbutanoyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.8.4] +synonym: "isovaleroyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.4] +synonym: "isovaleryl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.8.4] +xref: EC:1.3.8.4 +xref: MetaCyc:ISOVALERYL-COA-FAD-RXN +xref: Reactome:R-HSA-70745 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2" +xref: RHEA:12276 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0008471 +name: obsolete laccase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O." [EC:1.10.3.2] +synonym: "benzenediol:oxygen oxidoreductase activity" RELATED [EC:1.10.3.2] +synonym: "laccase activity" EXACT [] +synonym: "p-diphenol oxidase activity" RELATED [EC:1.10.3.2] +synonym: "urishiol oxidase activity" RELATED [EC:1.10.3.2] +synonym: "urushiol oxidase activity" RELATED [EC:1.10.3.2] +is_obsolete: true +replaced_by: GO:0016682 + +[Term] +id: GO:0008472 +name: obsolete metallocarboxypeptidase D activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid." [EC:3.4.17.22] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase D (cattle, human, mouse, rat)" RELATED [EC:3.4.17.22] +synonym: "gp180 (duck)" RELATED [EC:3.4.17.22] +synonym: "metallocarboxypeptidase D activity" EXACT [] +xref: EC:3.4.17.22 +xref: MetaCyc:3.4.17.22-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0008473 +name: ornithine cyclodeaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+)." [EC:4.3.1.12, RHEA:24368] +comment: Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases. +synonym: "L-ornithine ammonia-lyase (cyclizing)" EXACT [EC:4.3.1.12] +synonym: "L-ornithine ammonia-lyase (cyclizing; L-proline-forming)" EXACT [EC:4.3.1.12] +synonym: "OCD activity" EXACT [EC:4.3.1.12] +synonym: "ornithine cyclase (deaminating) activity" EXACT [EC:4.3.1.12] +synonym: "ornithine cyclase activity" EXACT [EC:4.3.1.12] +xref: EC:4.3.1.12 +xref: KEGG_REACTION:R00671 +xref: MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN +xref: RHEA:24368 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0008474 +name: palmitoyl-(protein) hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein." [EC:3.1.2.22] +subset: goslim_chembl +synonym: "palmitoyl-[protein] hydrolase" BROAD [EC:3.1.2.22] +synonym: "palmitoyl-protein hydrolase activity" EXACT [] +synonym: "palmitoyl-protein thioesterase activity" EXACT [] +synonym: "palmitoyl-protein thiolesterase activity" EXACT [] +xref: EC:3.1.2.22 +xref: MetaCyc:3.1.2.22-RXN +xref: Reactome:R-HSA-203613 "depalmitoylation of eNOS" +xref: Reactome:R-HSA-5690517 "PPT1 hydrolyses palmitoylated proteins" +xref: Reactome:R-HSA-8933328 "LYPLA2 hydrolyses PALM-C3,4-GAP43" +is_a: GO:0016790 ! thiolester hydrolase activity +is_a: GO:0098599 ! palmitoyl hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008475 +name: procollagen-lysine 5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2." [EC:1.14.11.4] +synonym: "collagen lysine hydroxylase activity" EXACT [EC:1.14.11.4] +synonym: "lysine hydroxylase activity" BROAD [EC:1.14.11.4] +synonym: "lysine,2-oxoglutarate 5-dioxygenase activity" BROAD [EC:1.14.11.4] +synonym: "lysine-2-oxoglutarate dioxygenase activity" BROAD [EC:1.14.11.4] +synonym: "lysyl hydroxylase activity" BROAD [EC:1.14.11.4] +synonym: "lysylprotocollagen dioxygenase activity" EXACT [EC:1.14.11.4] +synonym: "procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.11.4] +synonym: "procollagen-lysine,2-oxoglutarate 5-dioxygenase activity" EXACT [EC:1.14.11.4] +synonym: "protocollagen lysine dioxygenase activity" EXACT [EC:1.14.11.4] +synonym: "protocollagen lysine hydroxylase activity" EXACT [EC:1.14.11.4] +synonym: "protocollagen lysyl hydroxylase activity" EXACT [EC:1.14.11.4] +xref: EC:1.14.11.4 +xref: MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN +xref: Reactome:R-HSA-1981104 "Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines" +is_a: GO:0070815 ! peptidyl-lysine 5-dioxygenase activity + +[Term] +id: GO:0008476 +name: protein-tyrosine sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate." [EC:2.8.2.20] +subset: goslim_chembl +synonym: "3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity" EXACT [EC:2.8.2.20] +synonym: "protein-tyrosine sulphotransferase activity" EXACT [] +synonym: "tyrosylprotein sulfotransferase activity" EXACT [EC:2.8.2.20] +xref: EC:2.8.2.20 +xref: MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-8954262 "TPST1,2 transfer SO4(2-) from PAPS to PODXL2" +is_a: GO:0008146 ! sulfotransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008477 +name: purine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose." [EC:3.2.2.1] +synonym: "IAG-NH activity" RELATED [EC:3.2.2.1] +synonym: "IAG-nucleoside hydrolase activity" RELATED [EC:3.2.2.1] +synonym: "inosine-adenosine-guanosine preferring nucleoside hydrolase activity" NARROW [EC:3.2.2.1] +synonym: "N-D-ribosylpurine ribohydrolase activity" EXACT [EC:3.2.2.1] +synonym: "N-ribosyl purine ribohydrolase activity" EXACT [EC:3.2.2.1] +synonym: "nucleosidase activity" BROAD [EC:3.2.2.1] +synonym: "nucleosidase g activity" NARROW [EC:3.2.2.1] +synonym: "nucleoside hydrolase activity" BROAD [EC:3.2.2.1] +synonym: "purine beta-ribosidase activity" EXACT [EC:3.2.2.1] +synonym: "purine nucleosidase reaction" EXACT [] +synonym: "purine nucleoside hydrolase activity" EXACT [EC:3.2.2.1] +synonym: "purine ribonucleosidase activity" EXACT [EC:3.2.2.1] +synonym: "purine-nucleoside ribohydrolase activity" EXACT [EC:3.2.2.1] +synonym: "purine-specific nucleoside N-ribohydrolase activity" EXACT [EC:3.2.2.1] +synonym: "ribonucleoside hydrolase activity" EXACT [EC:3.2.2.1] +xref: EC:3.2.2.1 +xref: MetaCyc:PURINE-NUCLEOSIDASE-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0008478 +name: pyridoxal kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate." [EC:2.7.1.35] +synonym: "ATP:pyridoxal 5'-phosphotransferase activity" EXACT [EC:2.7.1.35] +synonym: "pyridoxal 5-phosphate-kinase activity" EXACT [EC:2.7.1.35] +synonym: "pyridoxal kinase (phosphorylating)" EXACT [EC:2.7.1.35] +synonym: "pyridoxal phosphokinase activity" EXACT [EC:2.7.1.35] +synonym: "pyridoxamine kinase activity" RELATED [EC:2.7.1.35] +synonym: "pyridoxine kinase activity" RELATED [EC:2.7.1.35] +synonym: "vitamin B(6) kinase activity" RELATED [EC:2.7.1.35] +synonym: "vitamin B6 kinase activity" RELATED [EC:2.7.1.35] +xref: EC:2.7.1.35 +xref: MetaCyc:PYRIDOXKIN-RXN +xref: Reactome:R-HSA-964958 "2xPDXK:2xZn2+ phosphorylates PXA" +xref: Reactome:R-HSA-964962 "2xPDKX:2xZn2+ phosphorylates PDX" +xref: Reactome:R-HSA-964970 "2xPDXK:2xZn2+ phosphorylates PXL" +xref: RHEA:10224 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008479 +name: queuine tRNA-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine." [EC:2.4.2.29] +synonym: "[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity" EXACT [EC:2.4.2.29] +synonym: "guanine insertion enzyme activity" RELATED [EC:2.4.2.29] +synonym: "guanine, queuine-tRNA transglycosylase activity" EXACT [EC:2.4.2.29] +synonym: "Q-insertase activity" EXACT [EC:2.4.2.29] +synonym: "queuine transfer ribonucleate ribosyltransferase activity" EXACT [EC:2.4.2.29] +synonym: "transfer ribonucleate glycosyltransferase activity" EXACT [EC:2.4.2.29] +synonym: "tRNA guanine transglycosidase activity" EXACT [EC:2.4.2.29] +synonym: "tRNA transglycosylase activity" EXACT [EC:2.4.2.29] +synonym: "tRNA-guanine transglycosylase activity" EXACT [EC:2.4.2.29] +xref: EC:2.4.2.29 +xref: MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-6782443 "QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr)" +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0008480 +name: sarcosine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein." [EC:1.5.8.3, RHEA:19793] +comment: Note that this was EC:1.5.99.1. +synonym: "monomethylglycine dehydrogenase activity" EXACT [EC:1.5.8.3] +synonym: "sarcosine N-demethylase activity" EXACT [EC:1.5.8.3] +synonym: "sarcosine:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.8.3] +synonym: "sarcosine:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.8.3] +xref: EC:1.5.8.3 +xref: KEGG_REACTION:R00611 +xref: MetaCyc:SARCOSINE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-6797913 "SARDH:FAD oxidatively demethylates SARC to Gly" +xref: RHEA:19793 +is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor + +[Term] +id: GO:0008481 +name: sphinganine kinase activity +namespace: molecular_function +alt_id: GO:0001728 +def: "Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate." [EC:2.7.1.91] +synonym: "ATP:sphinganine 1-phosphotransferase activity" EXACT [EC:2.7.1.91] +synonym: "dihydrosphingosine kinase (phosphorylating)" EXACT [EC:2.7.1.91] +synonym: "dihydrosphingosine kinase activity" EXACT [EC:2.7.1.91] +synonym: "sphingosine kinase (phosphorylating)" EXACT [EC:2.7.1.91] +synonym: "sphingosine kinase activity" RELATED [] +xref: EC:2.7.1.91 +xref: MetaCyc:SPHINGANINE-KINASE-RXN +xref: Reactome:R-HSA-428214 "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP" +xref: RHEA:15465 +is_a: GO:0001727 ! lipid kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008482 +name: sulfite oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate." [EC:1.8.3.1, RHEA:24600] +synonym: "sulfite:oxygen oxidoreductase activity" EXACT [EC:1.8.3.1] +synonym: "sulphite oxidase activity" EXACT [] +xref: EC:1.8.3.1 +xref: KEGG_REACTION:R00533 +xref: MetaCyc:PWY-5326 +xref: MetaCyc:SULFITE-OXIDASE-RXN +xref: Reactome:R-HSA-1614544 "Sulfite is oxidized to sulfate" +xref: RHEA:24600 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0008483 +name: transaminase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid." [ISBN:0198506732] +synonym: "aminotransferase activity" EXACT [] +xref: EC:2.6.1 +xref: Reactome:R-HSA-1237102 "Transamination of MOB to methionine" +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups + +[Term] +id: GO:0008484 +name: sulfuric ester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2." [GOC:ai] +synonym: "sulfatase activity" EXACT [] +synonym: "sulphuric ester hydrolase activity" EXACT [] +xref: EC:3.1.6 +xref: MetaCyc:ARYLSULFAT-RXN +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0008486 +name: diphosphoinositol-polyphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate." [EC:3.6.1.52] +synonym: "diphospho-myo-inositol-polyphosphate diphosphohydrolase activity" EXACT [EC:3.6.1.52] +synonym: "diphosphoinositol polyphosphate phosphohydrolase activity" EXACT [] +synonym: "diphosphoinositol-polyphosphate phosphohydrolase activity" EXACT [EC:3.6.1.52] +synonym: "DIPP activity" EXACT [EC:3.6.1.52] +xref: EC:3.6.1.52 +xref: KEGG_REACTION:R05777 +xref: MetaCyc:3.6.1.52-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0008487 +name: obsolete prenyl-dependent CAAX protease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "prenyl-dependent CAAX protease activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008488 +name: gamma-glutamyl carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide." [PMID:18374194] +xref: EC:4.1.1.90 +xref: Reactome:R-HSA-159752 "GGCX gamma-carboxylates PROS1(25-676) (pro-protein S)" +xref: Reactome:R-HSA-159761 "GGCX gamma-carboxylates F7(21-466) (pro-factor VII)" +xref: Reactome:R-HSA-159795 "GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain)" +xref: Reactome:R-HSA-159803 "GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX)" +xref: Reactome:R-HSA-159819 "GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain)" +xref: Reactome:R-HSA-159826 "GGCX gamma-carboxylates F2(25-622) (pro-prothrombin)" +xref: Reactome:R-HSA-163810 "GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6)" +xref: Reactome:R-HSA-163820 "GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z)" +xref: Reactome:R-HSA-6807214 "GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin)" +xref: RHEA:45140 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008489 +name: UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base." [MetaCyc:RXN-10764, PMID:9593693] +synonym: "LacCer synthase activity" EXACT [] +synonym: "lactosylceramide synthase activity" EXACT [] +synonym: "UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity" EXACT [] +xref: MetaCyc:RXN-10764 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0008490 +name: arsenite secondary active transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0008491 +def: "Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:jl] +synonym: "arsenite porter activity" RELATED [] +is_a: GO:0015105 ! arsenite transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0008492 +name: obsolete cAMP generating peptide activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a gene product. +synonym: "cAMP generating peptide activity" EXACT [] +synonym: "cyclic AMP generating peptide activity" EXACT [] +is_obsolete: true +consider: GO:0004016 +consider: GO:0005179 +consider: GO:0046058 + +[Term] +id: GO:0008493 +name: tetracycline transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [GOC:curators] +synonym: "tetracyclin transporter activity" EXACT [] +synonym: "tetracycline transporter activity" RELATED [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +relationship: part_of GO:0015904 ! tetracycline transmembrane transport + +[Term] +id: GO:0008494 +name: translation activator activity +namespace: molecular_function +def: "Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide." [GOC:ai] +is_a: GO:0090079 ! translation regulator activity, nucleic acid binding +relationship: part_of GO:0045727 ! positive regulation of translation + +[Term] +id: GO:0008495 +name: protoheme IX farnesyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate." [MetaCyc:HEMEOSYN-RXN] +synonym: "haem O synthase activity" EXACT [] +synonym: "heme A:farnesyltransferase activity" EXACT [PMID:9177788] +synonym: "heme O synthase activity" EXACT [] +synonym: "protohaem IX farnesyltransferase activity" EXACT [] +xref: EC:2.5.1 +xref: MetaCyc:HEMEOSYN-RXN +xref: Reactome:R-HSA-2995330 "COX10 transforms heme to heme O" +xref: RHEA:28070 +is_a: GO:0004311 ! farnesyltranstransferase activity + +[Term] +id: GO:0008496 +name: mannan endo-1,6-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans." [EC:3.2.1.101] +synonym: "1,6-alpha-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.101] +synonym: "1,6-beta-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.101] +synonym: "endo-1,6-beta-mannanase activity" EXACT [EC:3.2.1.101] +synonym: "endo-alpha-1->6-D-mannanase activity" EXACT [EC:3.2.1.101] +synonym: "endo-alpha-D-mannosidase activity" EXACT [] +synonym: "exo-1,6-beta-mannanase activity" EXACT [EC:3.2.1.101] +synonym: "mannan endo-1,6-beta-mannosidase activity" EXACT [EC:3.2.1.101] +xref: EC:3.2.1.101 +xref: MetaCyc:3.2.1.101-RXN +xref: Reactome:R-HSA-6799581 "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man" +is_a: GO:0004559 ! alpha-mannosidase activity + +[Term] +id: GO:0008498 +name: obsolete phospholipid scrambling +namespace: molecular_function +def: "OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions." [OMIM:604170] +comment: This term was made obsolete because it represents a biological process and not a molecular function. +synonym: "phospholipid scrambling" EXACT [] +is_obsolete: true +replaced_by: GO:0017121 + +[Term] +id: GO:0008499 +name: UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP." [PMID:10212226] +synonym: "beta-1,3-GalTase activity" BROAD [] +synonym: "beta3Gal-Ts activity" BROAD [] +synonym: "UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" EXACT [] +xref: Reactome:R-HSA-914010 "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein" +xref: Reactome:R-HSA-9603989 "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain" +is_a: GO:0035250 ! UDP-galactosyltransferase activity +is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity + +[Term] +id: GO:0008500 +name: obsolete glycine-, glutamate-, thienylcyclohexylpiperidine binding +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it is a conglomeration of three terms. +synonym: "glycine-, glutamate-, thienylcyclohexylpiperidine binding" EXACT [] +is_obsolete: true +consider: GO:0016594 +consider: GO:0016595 +consider: GO:0016596 + +[Term] +id: GO:0008502 +name: melatonin receptor activity +namespace: molecular_function +def: "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin." [GOC:ai, ISBN:0198506732] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0008503 +name: benzodiazepine receptor activity +namespace: molecular_function +def: "Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity." [GOC:jl] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'chloride channel activity ; GO:0005254', 'GABA receptor activity ; GO:0016917' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'. +is_a: GO:0030594 ! neurotransmitter receptor activity + +[Term] +id: GO:0008504 +name: monoamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015201 +def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] +xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" +xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" +xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" +xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines" +xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" +is_a: GO:0022804 ! active transmembrane transporter activity +relationship: part_of GO:0015844 ! monoamine transport + +[Term] +id: GO:0008506 +name: sucrose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in)." [TC:2.A.1.5.3] +synonym: "hydrogen/sucrose transporter activity" BROAD [] +synonym: "sucrose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0009669 ! sucrose:cation symporter activity + +[Term] +id: GO:0008507 +name: sodium:iodide symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in)." [TC:2.A.21.5.1] +synonym: "sodium/iodide symporter activity" EXACT [] +xref: Reactome:R-HSA-429591 "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol" +xref: Reactome:R-HSA-5658195 "Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol" +is_a: GO:0015111 ! iodide transmembrane transporter activity +is_a: GO:0015373 ! anion:sodium symporter activity + +[Term] +id: GO:0008508 +name: bile acid:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)." [TC:2.A.28.-.-] +synonym: "sodium/bile acid symporter activity" EXACT [] +xref: Reactome:R-HSA-194121 "Co-transport (influx) of bile salts and sodium ions by NTCP" +xref: Reactome:R-HSA-194187 "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-433089 "SOAT can transport taurolithocholate-3-sulphate" +is_a: GO:0015125 ! bile acid transmembrane transporter activity +is_a: GO:0140161 ! monocarboxylate:sodium symporter activity + +[Term] +id: GO:0008509 +name: anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a negatively charged ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] +synonym: "anion transporter activity" EXACT [] +xref: Reactome:R-HSA-166214 "FA anion flip-flops to the opposite surface" +is_a: GO:0015075 ! ion transmembrane transporter activity +relationship: part_of GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0008510 +name: sodium:bicarbonate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in)." [TC:2.A.31.2.1] +synonym: "sodium/bicarbonate cotransporter activity" BROAD [] +synonym: "sodium:bicarbonate cotransporter activity" BROAD [] +xref: Reactome:R-HSA-425483 "SLC4A5,7,9 cotransport Na+ with 3HCO3-" +xref: Reactome:R-HSA-5656219 "Defective SLC4A4 does not cotransport Na+ with 3HCO3-" +xref: Reactome:R-HSA-8878664 "SLC4A4 cotransports Na+ with 3HCO3-" +is_a: GO:0015370 ! solute:sodium symporter activity +is_a: GO:0140410 ! solute:bicarbonate symporter activity + +[Term] +id: GO:0008511 +name: sodium:potassium:chloride symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in)." [TC:2.A.30.1.1] +synonym: "sodium/potassium/chloride symporter activity" EXACT [] +xref: Reactome:R-HSA-426086 "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol" +xref: Reactome:R-HSA-5623588 "Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol" +is_a: GO:0009674 ! potassium:sodium symporter activity +is_a: GO:0015378 ! sodium:chloride symporter activity +is_a: GO:0015379 ! potassium:chloride symporter activity + +[Term] +id: GO:0008512 +name: sulfate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in)." [TC:2.A.53.-.-] +synonym: "sulfate/hydrogen symporter activity" EXACT [] +synonym: "sulfate:hydrogen symporter activity" EXACT [] +synonym: "sulphate:hydrogen symporter activity" EXACT [] +is_a: GO:0008271 ! secondary active sulfate transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015296 ! anion:cation symporter activity + +[Term] +id: GO:0008513 +name: secondary active organic cation transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015354 +def: "Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:curators] +synonym: "organic cation porter activity" RELATED [] +synonym: "polyspecific organic cation transmembrane transporter activity" NARROW [] +xref: Reactome:R-HSA-549241 "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol" +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0008514 +name: organic anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] +xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5" +is_a: GO:0008509 ! anion transmembrane transporter activity +relationship: part_of GO:0015711 ! organic anion transport + +[Term] +id: GO:0008515 +name: sucrose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0019188 +def: "Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "sucrose permease (PTS) activity" EXACT [] +synonym: "sucrose permease activity" RELATED [] +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0015770 ! sucrose transport + +[Term] +id: GO:0008516 +name: hexose uniporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in)." [TC:2.A.1.1.5] +is_a: GO:0015149 ! hexose transmembrane transporter activity +is_a: GO:0015292 ! uniporter activity + +[Term] +id: GO:0008517 +name: folic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:ai] +synonym: "folate transmembrane transporter activity" EXACT [] +synonym: "folate transporter activity" EXACT [] +synonym: "folic acid transporter activity" RELATED [] +synonym: "vitamin B9 transporter activity" EXACT [] +synonym: "vitamin M transporter activity" EXACT [] +xref: Reactome:R-HSA-200646 "Cytosolic folate export across the plasma membrane" +xref: Reactome:R-HSA-200652 "Extracellular 5-methyltetrahydrofolate import across the plasma membrane" +xref: Reactome:R-HSA-200680 "Cytosolic tetrahydrofolate import across the inner mitochondrial membrane" +xref: Reactome:R-HSA-200720 "Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane" +xref: Reactome:R-HSA-200729 "Extracellular folate import across the plasma membrane" +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0015884 ! folic acid transport + +[Term] +id: GO:0008518 +name: folate:anion antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF." [GOC:mtg_transport, PMID:21568705, PMID:24745983, TC:2.A.48] +synonym: "reduced folate carrier activity" RELATED [] +synonym: "reduced folate transmembrane transporter activity" RELATED [] +synonym: "reduced folate transporter" RELATED [] +xref: TC:2.A.48 +is_a: GO:0008517 ! folic acid transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15461 xsd:anyURI + +[Term] +id: GO:0008519 +name: ammonium transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0051739 +def: "Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals." [GOC:go_curators, ISBN:0198506732] +synonym: "ammonia transmembrane transporter activity" EXACT [] +xref: Reactome:R-HSA-444393 "RhCG mediates ammonium influx into kidney collecting duct cells" +xref: Reactome:R-HSA-444416 "RHAG transports NH4+ from cytosol to extracellular region (red blood cells)" +xref: Reactome:R-HSA-444419 "RhBG mediates ammonium effflux out of kidney collecting duct cells" +xref: Reactome:R-HSA-446277 "RhCG mediates ammonium efflux out of kidney collecting duct cells" +xref: Reactome:R-HSA-446278 "RhBG mediates ammonium influx into kidney collecting duct cells" +xref: Reactome:R-HSA-5623051 "Defective RHAG does not transport NH4+ from cytosol to extracellular region (rbc)" +xref: RHEA:28747 +is_a: GO:0015077 ! monovalent inorganic cation transmembrane transporter activity +relationship: part_of GO:0072488 ! ammonium transmembrane transport + +[Term] +id: GO:0008520 +name: L-ascorbate:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ascorbate(out) + Na+(out) = ascorbate(in) + Na+(in)." [TC:2.A.40.6.1] +synonym: "sodium-dependent L-ascorbic acid transporter" RELATED [] +is_a: GO:0005343 ! organic acid:sodium symporter activity +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015229 ! L-ascorbic acid transmembrane transporter activity + +[Term] +id: GO:0008521 +name: acetyl-CoA transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GOC:ai] +synonym: "acetyl-CoA transporter activity" RELATED [] +xref: Reactome:R-HSA-5649742 "Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen" +xref: Reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:0071077 ! adenosine 3',5'-bisphosphate transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0015876 ! acetyl-CoA transport + +[Term] +id: GO:0008523 +name: sodium-dependent multivitamin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate." [TC:2.A.21.5.2] +xref: Reactome:R-HSA-199206 "SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol" +xref: Reactome:R-HSA-199219 "SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol" +xref: Reactome:R-HSA-429581 "SLC5A6 transports vitamins from extracellular region to cytosol" +is_a: GO:0015370 ! solute:sodium symporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity + +[Term] +id: GO:0008525 +name: phosphatidylcholine transporter activity +namespace: molecular_function +def: "Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:ai, ISBN:0198506732] +synonym: "phosphatidylcholine transmembrane transporter activity" NARROW [GOC:bf, GOC:vw] +is_a: GO:0005548 ! phospholipid transporter activity + +[Term] +id: GO:0008526 +name: phosphatidylinositol transfer activity +namespace: molecular_function +alt_id: GO:0120018 +def: "Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane phosphatidylinositol transfer activity" NARROW [] +synonym: "intermembrane phosphotidylinositol transfer activity" NARROW [] +synonym: "phosphatidylinositol carrier activity" EXACT [] +synonym: "phosphatidylinositol transfer activity" EXACT [] +synonym: "phosphatidylinositol transporter activity" BROAD [] +xref: Reactome:R-HSA-8869241 "PITPNM1,2,3 exchange PI for PA" +xref: Reactome:R-HSA-8874470 "TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane" +is_a: GO:0120014 ! phospholipid transfer activity +relationship: has_part GO:0035091 ! phosphatidylinositol binding +created_by: krc +creation_date: 2017-03-17T04:22:47Z + +[Term] +id: GO:0008527 +name: taste receptor activity +namespace: molecular_function +def: "Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste." [GOC:dph] +synonym: "gustatory receptor" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste + +[Term] +id: GO:0008528 +name: G protein-coupled peptide receptor activity +namespace: molecular_function +def: "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:dph, GOC:tb] +synonym: "G protein coupled peptide receptor activity" EXACT [] +synonym: "G-protein coupled peptide receptor activity" EXACT [] +synonym: "peptide receptor activity, G protein coupled" EXACT [] +synonym: "peptide receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0001653 ! peptide receptor activity +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0008529 +name: obsolete endogenous peptide receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an intracellular peptide to initiate a change in cell activity." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "endogenous peptide receptor activity" EXACT [] +is_obsolete: true +consider: GO:0001653 +consider: GO:0005622 + +[Term] +id: GO:0008530 +name: obsolete exogenous peptide receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an extracellular peptide to initiate a change in cell activity." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "exogenous peptide receptor activity" EXACT [] +is_obsolete: true +consider: GO:0001653 +consider: GO:0005576 + +[Term] +id: GO:0008531 +name: riboflavin kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+)." [EC:2.7.1.26, RHEA:14357] +synonym: "ATP:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.26] +synonym: "FK" RELATED [EC:2.7.1.26] +synonym: "flavokinase activity" EXACT [EC:2.7.1.26] +synonym: "riboflavin kinase (phosphorylating)" EXACT [EC:2.7.1.26] +synonym: "riboflavine kinase activity" EXACT [EC:2.7.1.26] +xref: EC:2.7.1.26 +xref: KEGG_REACTION:R00549 +xref: MetaCyc:RIBOFLAVINKIN-RXN +xref: Reactome:R-HSA-196964 "RFK:Mg2+ phosphorylates RIB" +xref: RHEA:14357 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008532 +name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.149] +synonym: "galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "GnTE activity" EXACT [EC:2.4.1.149] +synonym: "N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "poly-N-acetyllactosamine extension enzyme activity" BROAD [EC:2.4.1.149] +synonym: "UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.149] +synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149] +synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149] +xref: EC:2.4.1.149 +xref: MetaCyc:2.4.1.149-RXN +xref: Reactome:R-HSA-2025724 "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG" +xref: RHEA:14389 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0008533 +name: obsolete astacin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'." [EC:3.4.24.21] +comment: This term was made obsolete because it represents a gene product. +synonym: "astacin activity" EXACT [] +synonym: "Astacus proteinase activity" EXACT [EC:3.4.24.21] +synonym: "astacus proteinase activity" NARROW [EC:3.4.24.21] +synonym: "crayfish small-molecule proteinase activity" NARROW [EC:3.4.24.21] +xref: EC:3.4.24.21 +xref: MetaCyc:3.4.24.21-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008534 +name: oxidized purine nucleobase lesion DNA N-glycosylase activity +namespace: molecular_function +alt_id: GO:0003907 +def: "Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296] +comment: Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'. +synonym: "2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity" EXACT [EC:3.2.2.23] +synonym: "2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity" EXACT [EC:3.2.2.23] +synonym: "8-oxoguanine DNA glycosylase activity" BROAD [] +synonym: "bifunctional DNA glycosylase activity" BROAD [] +synonym: "deoxyribonucleate glycosidase activity" EXACT [EC:3.2.2.23] +synonym: "DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]" RELATED [EC:3.2.2.23] +synonym: "DNA glycosylase/AP-lyase activity" BROAD [] +synonym: "DNA glycosylase/beta-lyase activity" BROAD [] +synonym: "DNA-formamidopyrimidine glycosylase activity" EXACT [] +synonym: "Fapy-DNA glycosylase activity" EXACT [EC:3.2.2.23] +synonym: "formamidopyrimidine-DNA glycosylase activity" EXACT [] +synonym: "Fpg protein" RELATED [EC:3.2.2.23] +synonym: "oxidized purine base lesion DNA N-glycosylase activity" EXACT [] +synonym: "purine-specific oxidized base lesion DNA N-glycosylase activity" RELATED [] +xref: EC:3.2.2.23 +xref: MetaCyc:3.2.2.23-RXN +xref: Reactome:R-HSA-110229 "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase" +xref: Reactome:R-HSA-110243 "Cleavage of 8-oxoguanine by OGG1 glycosylase" +xref: Reactome:R-HSA-110244 "Cleavage of formamidopyrimidine (FapyG) by OGG1 glycosylase" +is_a: GO:0000702 ! oxidized base lesion DNA N-glycosylase activity + +[Term] +id: GO:0008535 +name: respiratory chain complex IV assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms." [GOC:jl, http://www.med.wright.edu/bmb/lp/lplab.htm] +synonym: "cytochrome c oxidase biogenesis" BROAD [] +synonym: "cytochrome c oxidase complex assembly" EXACT [] +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0008536 +name: Ran GTPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly." [GOC:rn, PMID:12787777, PMID:14726649] +synonym: "Ran protein binding" EXACT [] +synonym: "Ran-binding protein" RELATED [] +is_a: GO:0017016 ! Ras GTPase binding + +[Term] +id: GO:0008537 +name: proteasome activator complex +namespace: cellular_component +def: "A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex." [GOC:rb] +synonym: "PA28" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0022624 ! proteasome accessory complex + +[Term] +id: GO:0008538 +name: obsolete proteasome activator activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:rn, PMID:10428771] +comment: The term was made obsolete because 'proteasome' is not a valid molecular function term. +synonym: "PA28" NARROW [] +synonym: "proteasome activator activity" EXACT [] +is_obsolete: true +consider: GO:0061133 +consider: GO:0061136 + +[Term] +id: GO:0008539 +name: obsolete proteasome inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:mah] +comment: The term was made obsolete because 'proteasome' is not a valid molecular function term. +synonym: "PI-31" NARROW [] +synonym: "proteasome inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0004866 +consider: GO:0061136 + +[Term] +id: GO:0008540 +name: proteasome regulatory particle, base subcomplex +namespace: cellular_component +def: "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex." [GOC:mtg_sensu, GOC:rb] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005838 ! proteasome regulatory particle + +[Term] +id: GO:0008541 +name: proteasome regulatory particle, lid subcomplex +namespace: cellular_component +def: "The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:rb] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005838 ! proteasome regulatory particle + +[Term] +id: GO:0008542 +name: visual learning +namespace: biological_process +def: "Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue." [GOC:jid, ISBN:0582227089] +synonym: "spatial learning" RELATED [] +is_a: GO:0007632 ! visual behavior +is_a: GO:0008306 ! associative learning + +[Term] +id: GO:0008543 +name: fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." [GOC:ceb] +synonym: "FGF receptor signaling pathway" EXACT [] +synonym: "FGF receptor signalling pathway" EXACT [] +synonym: "FGFR signaling pathway" EXACT [] +synonym: "fibroblast growth factor receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +relationship: part_of GO:0044344 ! cellular response to fibroblast growth factor stimulus + +[Term] +id: GO:0008544 +name: epidermis development +namespace: biological_process +def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003] +synonym: "hypodermis development" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0009888 ! tissue development +property_value: RO:0002161 NCBITaxon:33090 + +[Term] +id: GO:0008545 +name: JUN kinase kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase." [GOC:bf, PMID:11057897, PMID:11790549] +synonym: "JNKK" EXACT [] +xref: Reactome:R-HSA-168162 "Phosphorylation of human JNKs by activated MKK4/MKK7" +is_a: GO:0004708 ! MAP kinase kinase activity +relationship: part_of GO:0007257 ! activation of JUN kinase activity + +[Term] +id: GO:0008546 +name: obsolete microtubule/chromatin interaction +namespace: biological_process +def: "OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins." [PMID:10322137] +comment: This term was made obsolete because it represents a molecular function. +synonym: "microtubule/chromatin interaction" EXACT [] +is_obsolete: true +consider: GO:0003677 +consider: GO:0003682 +consider: GO:0008017 +consider: GO:0030674 + +[Term] +id: GO:0008547 +name: obsolete protein-synthesizing GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs." [EC:3.6.5.3, MetaCyc:3.6.1.48-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "protein-synthesizing GTPase activity" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0006412 +consider: GO:0008135 + +[Term] +id: GO:0008548 +name: obsolete signal-recognition-particle GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis." [EC:3.6.5.4, MetaCyc:3.6.1.49-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "signal-recognition-particle GTPase activity" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0005786 + +[Term] +id: GO:0008549 +name: obsolete dynamin GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles." [EC:3.6.5.5, MetaCyc:3.6.1.50-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "dynamin GTPase activity" EXACT [] +synonym: "dynamine GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0006897 + +[Term] +id: GO:0008550 +name: obsolete tubulin GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others." [EC:3.6.5.6, MetaCyc:3.6.1.51-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "tubulin GTPase activity" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0007021 + +[Term] +id: GO:0008551 +name: cadmium transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +alt_id: GO:0008561 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out)." [EC:3.6.3.3] +synonym: "ATP phosphohydrolase (Cd2+-exporting)" EXACT [EC:3.6.3.3] +synonym: "cadmium exporting ATPase activity" EXACT [] +synonym: "cadmium-exporting ATPase activity" EXACT [] +synonym: "cadmium-translocating P-type ATPase activity" RELATED [EC:3.6.3.3] +synonym: "Cd(2+)-exporting ATPase activity" EXACT [EC:3.6.3.3] +synonym: "Cd2+-exporting ATPase activity" EXACT [EC:3.6.3.3] +xref: EC:3.6.3.3 +xref: MetaCyc:3.6.3.3-RXN +xref: RHEA:12132 +is_a: GO:0015434 ! ATPase-coupled cadmium transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism + +[Term] +id: GO:0008552 +name: obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+." [TC:3.A.3.6.2] +comment: This term was made obsolete because it represents more than one molecular function. +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0005385 +consider: GO:0015086 +consider: GO:0015087 +consider: GO:0015094 +consider: GO:0015099 +consider: GO:0015662 + +[Term] +id: GO:0008553 +name: proton-exporting ATPase activity, phosphorylative mechanism +namespace: molecular_function +alt_id: GO:0036442 +def: "Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle." [EC:7.1.2.1] +synonym: "H(+)-transporting ATPase activity" BROAD [EC:7.1.2.1] +synonym: "H+-exporting ATPase activity" EXACT [EC:7.1.2.1] +synonym: "H+-transporting ATPase" BROAD [EC:7.1.2.1] +synonym: "hydrogen exporting ATPase activity, phosphorylative mechanism" EXACT [] +synonym: "hydrogen-/sodium-translocating ATPase activity" RELATED [] +synonym: "hydrogen-exporting ATPase activity" BROAD [] +synonym: "hydrogen-exporting ATPase activity, phosphorylative mechanism" RELATED [] +synonym: "P-type H(+)-exporting ATPase activity" BROAD [EC:7.1.2.1] +synonym: "proton transport ATPase activity" RELATED [EC:7.1.2.1] +synonym: "proton-exporting ATPase activity" BROAD [] +synonym: "proton-translocating ATPase activity" EXACT [EC:7.1.2.1] +synonym: "proton-transporting ATPase activity" EXACT [GOC:bf] +xref: EC:7.1.2.1 +xref: MetaCyc:3.6.3.6-RXN +xref: RHEA:20852 +is_a: GO:0009678 ! pyrophosphate hydrolysis-driven proton transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity +created_by: bf +creation_date: 2013-09-30T16:56:16Z + +[Term] +id: GO:0008554 +name: sodium transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism." [EC:7.2.2.3] +synonym: "ATP phosphohydrolase (Na+-exporting)" RELATED [EC:7.2.2.3] +synonym: "hydrogen-/sodium-translocating ATPase activity" RELATED [] +synonym: "Na(+)-exporting ATPase activity" RELATED [EC:7.2.2.3] +synonym: "Na(+)-transporting ATPase activity" BROAD [EC:7.2.2.3] +synonym: "Na+-exporting ATPase activity" RELATED [EC:7.2.2.3] +synonym: "Na+-transporting ATPase activity" EXACT [EC:7.2.2.3] +synonym: "sodium exporting ATPase activity, phosphorylative mechanism" RELATED [] +synonym: "sodium transport ATPase activity" RELATED [EC:7.2.2.3] +synonym: "sodium-exporting ATPase activity" RELATED [EC:7.2.2.3] +synonym: "sodium-exporting ATPase activity, phosphorylative mechanism" RELATED [] +synonym: "sodium-translocating P-type ATPase activity" RELATED [EC:7.2.2.3] +xref: EC:7.2.2.3 +xref: MetaCyc:3.6.3.7-RXN +xref: RHEA:14633 +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0008555 +name: ATPase-coupled chloride transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in)." [EC:3.6.3.11] +synonym: "ATP phosphohydrolase (Cl--importing)" EXACT [EC:3.6.3.11] +synonym: "ATP-dependent chloride transmembrane transporter activity" EXACT [] +synonym: "chloride ABC transporter" NARROW [] +synonym: "chloride transporting ATPase activity" EXACT [] +synonym: "chloride-motive ATPase activity" EXACT [EC:3.6.3.11] +synonym: "chloride-translocating ATPase activity" EXACT [EC:3.6.3.11] +synonym: "chloride-transporting ATPase activity" EXACT [] +synonym: "Cl(-)-transporting ATPase activity" EXACT [EC:3.6.3.11] +synonym: "Cl--motive ATPase activity" EXACT [EC:3.6.3.11] +synonym: "Cl--translocating ATPase activity" EXACT [EC:3.6.3.11] +synonym: "Cl--transporting ATPase activity" EXACT [EC:3.6.3.11] +xref: EC:3.6.3.11 +xref: MetaCyc:3.6.3.11-RXN +xref: RHEA:24128 +is_a: GO:0015108 ! chloride transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0008556 +name: potassium transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +alt_id: GO:0015618 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in)." [EC:7.2.2.6] +synonym: "ATP phosphohydrolase (K+-importing)" RELATED [EC:7.2.2.6] +synonym: "ATP-dependent potassium transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled potassium transmembrane transporter activity" RELATED [] +synonym: "K(+)-importing ATPase activity" NARROW [EC:7.2.2.6] +synonym: "K(+)-transporting ATPase activity" EXACT [EC:7.2.2.6] +synonym: "K+-importing ATPase activity" RELATED [EC:7.2.2.6] +synonym: "K+-transporting ATPase activity" EXACT [] +synonym: "potassium ABC transporter" NARROW [] +synonym: "potassium transporting ATPase activity" EXACT [] +synonym: "potassium-importing ATPase activity" NARROW [EC:7.2.2.6] +synonym: "potassium-transporting ATPase activity" EXACT [] +synonym: "potassium-uptake-ATPase activity" EXACT [] +xref: EC:7.2.2.6 +xref: RHEA:16777 +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0008558 +name: ATPase-coupled guanine transmembrane transporter activity +namespace: molecular_function +def: "Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in)." [EC:7.6.2.6] +synonym: "ATP phosphohydrolase (guanine-importing)" EXACT [EC:7.6.2.6] +synonym: "ATP-dependent guanine transmembrane transporter activity" EXACT [] +synonym: "guanine ABC transporter" NARROW [] +synonym: "guanine-transporting ATPase activity" EXACT [EC:7.6.2.6] +xref: EC:7.6.2.6 +xref: MetaCyc:3.6.3.37-RXN +xref: RHEA:20832 +is_a: GO:0015208 ! guanine transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0008559 +name: ATPase-coupled xenobiotic transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005226 +alt_id: GO:0008560 +def: "Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out)." [EC:7.6.2.2] +synonym: "ATP phosphohydrolase (xenobiotic-exporting)" EXACT [EC:7.6.2.2] +synonym: "ATP-dependent xenobiotic transmembrane transporter activity" EXACT [] +synonym: "MDR protein" RELATED [EC:7.6.2.2] +synonym: "multidrug resistance exporter" RELATED [] +synonym: "multidrug-resistance protein" RELATED [] +synonym: "P-glycoprotein" RELATED [EC:7.6.2.2] +synonym: "PDR protein" RELATED [EC:7.6.2.2] +synonym: "pleiotropic-drug-resistance protein" RELATED [EC:7.6.2.2] +synonym: "xenobiotic ABC transporter" NARROW [] +synonym: "xenobiotic transmembrane transporting ATPase activity" EXACT [] +xref: EC:7.6.2.2 +xref: MetaCyc:3.6.3.44-RXN +xref: Reactome:R-HSA-1467457 "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region" +xref: Reactome:R-HSA-2161506 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate" +xref: Reactome:R-HSA-2161538 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate" +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0008563 +name: obsolete alpha-factor sex pheromone exporter +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process." [EC:3.6.3.48] +comment: This term was made obsolete because this function does not exist; alpha-factor is secreted by the classical secretion pathway and not exported. +synonym: "alpha-factor sex pheromone exporter" EXACT [] +synonym: "alpha-factor-transporting ATPase" RELATED [] +is_obsolete: true + +[Term] +id: GO:0008564 +name: protein-exporting ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins." [EC:7.4.2.8] +synonym: "ATP phosphohydrolase (protein-secreting)" EXACT [EC:7.4.2.8] +synonym: "protein-secreting ATPase activity" EXACT [] +xref: EC:7.4.2.8 +xref: MetaCyc:3.6.3.50-RXN +is_a: GO:0015462 ! ATPase-coupled protein transmembrane transporter activity + +[Term] +id: GO:0008565 +name: obsolete protein transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells." [ISBN:0198506732] +comment: This term was obsoleted because is has been inconsistently used. +synonym: "enzyme transporter activity" NARROW [] +synonym: "holin" RELATED [] +synonym: "protein transport chaperone" NARROW [GOC:dph, GOC:mah, GOC:tb] +synonym: "secretin" RELATED [] +xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex" +xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane" +xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen" +is_obsolete: true + +[Term] +id: GO:0008566 +name: mitochondrial protein-transporting ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex." [EC:7.4.2.3] +comment: See also the cellular component term 'mitochondrial inner membrane presequence translocase complex ; GO:0005744'. +synonym: "ATP phosphohydrolase (mitochondrial protein-importing) activity" EXACT [EC:7.4.2.3] +xref: EC:7.4.2.3 +xref: MetaCyc:3.6.3.51-RXN +is_a: GO:0015462 ! ATPase-coupled protein transmembrane transporter activity + +[Term] +id: GO:0008567 +name: obsolete dynein ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome." [EC:3.6.4.2] +comment: This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. +synonym: "dynein ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0003777 +consider: GO:0007018 + +[Term] +id: GO:0008568 +name: microtubule-severing ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP." [EC:5.6.1.1, PMID:10910766] +comment: See also the cellular component term 'katanin complex ; GO:0008352'. +synonym: "ATP phosphohydrolase (tubulin-dimerizing)" EXACT [] +synonym: "katanin activity" NARROW [EC:5.6.1.1] +xref: EC:5.6.1.1 +xref: MetaCyc:3.6.4.3-RXN +is_a: GO:0016887 ! ATPase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0051013 ! microtubule severing + +[Term] +id: GO:0008569 +name: ATP-dependent microtubule motor activity, minus-end-directed +namespace: molecular_function +def: "Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP." [EC:5.6.1.4, GOC:mah, GOC:vw] +synonym: "ATP-dependent minus-end-directed microtubule motor activity" EXACT [] +synonym: "kinesin ATP phosphohydrolase (minus-end-directed)" EXACT [] +synonym: "minus-end-directed ATP-dependent microtubule motor activity" EXACT [] +synonym: "minus-end-directed kinesin ATPase activity" EXACT [] +synonym: "minus-end-directed microtubule motor activity" BROAD [] +xref: EC:5.6.1.4 +xref: MetaCyc:3.6.4.5-RXN +is_a: GO:1990939 ! ATP-dependent microtubule motor activity + +[Term] +id: GO:0008570 +name: obsolete myosin ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction." [EC:3.6.4.1] +comment: This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. +synonym: "myosin ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0000146 +consider: GO:0030048 + +[Term] +id: GO:0008571 +name: obsolete non-chaperonin molecular chaperone ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin." [EC:3.6.4.10] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "non-chaperonin molecular chaperone ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016887 +consider: GO:0006457 + +[Term] +id: GO:0008572 +name: obsolete nucleoplasmin ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes." [EC:3.6.4.11] +comment: This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. +synonym: "nucleoplasmin ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016887 +consider: GO:0006333 + +[Term] +id: GO:0008573 +name: obsolete peroxisome-assembly ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle." [EC:3.6.4.7] +comment: This term was made obsolete because it incorporates process information. +synonym: "peroxisome-assembly ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016887 +consider: GO:0007031 + +[Term] +id: GO:0008574 +name: ATP-dependent microtubule motor activity, plus-end-directed +namespace: molecular_function +def: "Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP." [EC:5.6.1.3, GOC:vw] +synonym: "ATP-dependent plus-end-directed microtubule motor activity" EXACT [] +synonym: "kinesin activity" RELATED [EC:5.6.1.3] +synonym: "kinesin ATP phosphohydrolase (plus-end-directed)" EXACT [] +synonym: "plus-end-directed ATP-dependent microtubule motor activity" EXACT [] +synonym: "plus-end-directed kinesin ATPase activity" EXACT [] +synonym: "plus-end-directed microtubule motor activity" BROAD [] +xref: EC:5.6.1.3 +xref: MetaCyc:3.6.4.4-RXN +is_a: GO:1990939 ! ATP-dependent microtubule motor activity + +[Term] +id: GO:0008575 +name: obsolete proteasome ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome." [EC:3.6.4.8] +comment: This term was made obsolete because it mentions a component term in the term text string. +synonym: "proteasome ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0016887 + +[Term] +id: GO:0008576 +name: obsolete vesicle-fusing ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments." [EC:3.6.4.6] +comment: This term was made obsolete because it incorporates process information. +synonym: "vesicle-fusing ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016887 +consider: GO:0016192 +consider: GO:0061025 + +[Term] +id: GO:0008579 +name: JUN kinase phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate." [GOC:mah] +is_a: GO:0008138 ! protein tyrosine/serine/threonine phosphatase activity + +[Term] +id: GO:0008580 +name: obsolete cytoskeletal regulator activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because 'cytoskeleton' is not an activity, and regulation of its distribution or modification belongs in the process ontology. +synonym: "cytoskeletal regulator activity" EXACT [] +is_obsolete: true +consider: GO:0007010 + +[Term] +id: GO:0008581 +name: obsolete ubiquitin-specific protease 5 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin." [ISBN:0120793709, MEROPS:c19p001] +comment: This term was made obsolete because it represents a gene product. +synonym: "ubiquitin isopeptidase T activity" EXACT [] +synonym: "ubiquitin-specific protease 5 activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004843 + +[Term] +id: GO:0008582 +name: regulation of synaptic growth at neuromuscular junction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions." [GOC:go_curators] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0051963 ! regulation of synapse assembly +is_a: GO:1904396 ! regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051124 ! synaptic growth at neuromuscular junction +relationship: regulates GO:0051124 ! synaptic growth at neuromuscular junction + +[Term] +id: GO:0008583 +name: mystery cell differentiation +namespace: biological_process +def: "The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster." [ISBN:0632030488, PMID:1295747] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0008584 +name: male gonad development +namespace: biological_process +def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid] +synonym: "testicular development" EXACT [GOC:sl] +synonym: "testis development" EXACT [GOC:sl] +is_a: GO:0008406 ! gonad development +relationship: part_of GO:0046546 ! development of primary male sexual characteristics + +[Term] +id: GO:0008585 +name: female gonad development +namespace: biological_process +alt_id: GO:0061039 +def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb] +synonym: "ovarian development" RELATED [GOC:sl] +synonym: "ovary development" RELATED [GOC:sl] +is_a: GO:0008406 ! gonad development +relationship: part_of GO:0046545 ! development of primary female sexual characteristics +property_value: RO:0002161 NCBITaxon:3398 + +[Term] +id: GO:0008586 +name: imaginal disc-derived wing vein morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized." [GOC:mtg_sensu] +synonym: "wing vein morphogenesis" EXACT [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis + +[Term] +id: GO:0008587 +name: imaginal disc-derived wing margin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade." [GOC:bf, GOC:mtg_sensu, ISBN:0879694238] +comment: See also the fly_anatomy.ontology term 'wing margin ; FBbt:00005378'. +synonym: "wing margin morphogenesis" EXACT [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis + +[Term] +id: GO:0008589 +name: regulation of smoothened signaling pathway +namespace: biological_process +alt_id: GO:0007226 +alt_id: GO:0043109 +def: "Any process that modulates the frequency, rate or extent of smoothened signaling." [GOC:go_curators] +synonym: "regulation of hedgehog signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "regulation of hh signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "regulation of smoothened activity" RELATED [] +synonym: "regulation of smoothened by patched" RELATED [] +synonym: "regulation of smoothened receptor activity by patched" RELATED [] +synonym: "regulation of smoothened signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007224 ! smoothened signaling pathway +relationship: regulates GO:0007224 ! smoothened signaling pathway + +[Term] +id: GO:0008591 +name: regulation of Wnt signaling pathway, calcium modulating pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "regulation of frizzled-2 signalling pathway" EXACT [] +synonym: "regulation of Wnt receptor signaling pathway, calcium modulating pathway" EXACT [] +synonym: "regulation of Wnt-activated signaling pathway, calcium modulating pathway" EXACT [GOC:signaling] +is_a: GO:2000050 ! regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway +relationship: regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway + +[Term] +id: GO:0008592 +name: regulation of Toll signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] +synonym: "regulation of Tl signaling pathway" EXACT [] +synonym: "regulation of Tl signalling pathway" EXACT [] +synonym: "regulation of Toll signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008063 ! Toll signaling pathway +relationship: regulates GO:0008063 ! Toll signaling pathway + +[Term] +id: GO:0008593 +name: regulation of Notch signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] +synonym: "regulation of N signaling pathway" EXACT [] +synonym: "regulation of N signalling pathway" EXACT [] +synonym: "regulation of Notch signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007219 ! Notch signaling pathway +relationship: regulates GO:0007219 ! Notch signaling pathway + +[Term] +id: GO:0008594 +name: photoreceptor cell morphogenesis +namespace: biological_process +def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah] +synonym: "photoreceptor development" RELATED [] +is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation +relationship: part_of GO:0042461 ! photoreceptor cell development + +[Term] +id: GO:0008595 +name: anterior/posterior axis specification, embryo +namespace: biological_process +def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] +synonym: "anterior/posterior axis determination, embryo" RELATED [GOC:dph] +is_a: GO:0000578 ! embryonic axis specification +is_a: GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0007351 ! tripartite regional subdivision + +[Term] +id: GO:0008597 +name: calcium-dependent protein serine/threonine phosphatase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase." [EC:3.1.3.16, GOC:ai] +synonym: "calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity" NARROW [] +xref: Reactome:R-HSA-139906 "Activation of BAD by calcineurin" +is_a: GO:0019888 ! protein phosphatase regulator activity +relationship: regulates GO:0004723 ! calcium-dependent protein serine/threonine phosphatase activity + +[Term] +id: GO:0008603 +name: cAMP-dependent protein kinase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme cAMP-dependent protein kinase." [GOC:ai] +synonym: "3',5' cAMP-dependent protein kinase regulator activity" EXACT [] +synonym: "3',5'-cAMP-dependent protein kinase regulator activity" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity" EXACT [] +synonym: "cAMP-dependent protein kinase, intrinsic regulator activity" NARROW [] +synonym: "cyclic AMP-dependent protein kinase regulator activity" EXACT [] +is_a: GO:0019887 ! protein kinase regulator activity +relationship: part_of GO:2000479 ! regulation of cAMP-dependent protein kinase activity + +[Term] +id: GO:0008605 +name: obsolete protein kinase CK2 regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulation of the activity of the enzyme protein kinase CK2." [GOC:ai] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "casein kinase II, regulator" EXACT [] +synonym: "protein kinase CK2 regulator activity" EXACT [] +synonym: "protein kinase CK2, intrinsic regulator activity" NARROW [] +is_obsolete: true +replaced_by: GO:0019887 + +[Term] +id: GO:0008607 +name: phosphorylase kinase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme phosphorylase kinase." [EC:2.7.11.19] +synonym: "phosphorylase kinase, intrinsic regulator activity" NARROW [] +xref: EC:2.7.1 +is_a: GO:0019887 ! protein kinase regulator activity + +[Term] +id: GO:0008608 +name: attachment of spindle microtubules to kinetochore +namespace: biological_process +alt_id: GO:0051313 +def: "The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex." [GOC:vw, PMID:10322137] +comment: This class covers all attachments of spindle microtubules to the kinetochore, including the many incorrect attachments which initially form and are later corrected to stable attachments with the correct orientation for segregation to proceed (sister chromatid biorientation). +synonym: "amphotelic attachment" RELATED [] +synonym: "attachment of spindle microtubules to chromosome" EXACT [] +synonym: "bipolar attachment" RELATED [] +synonym: "kinetochore microtubule interaction" BROAD [] +synonym: "kinetochore-microtubule attachment" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "kinetochore-microtubule interaction" BROAD [] +synonym: "microtubule anchoring at kinetochore" EXACT [] +synonym: "microtubule and chromosome interaction" BROAD [] +synonym: "microtubule and kinetochore interaction" RELATED [] +synonym: "microtubule capture" NARROW [] +synonym: "spindle chromosome attachment" EXACT [] +synonym: "spindle kinetochore attachment" EXACT [] +synonym: "spindle-chromosome interaction" BROAD [] +is_a: GO:0022402 ! cell cycle process +relationship: has_part GO:0008017 ! microtubule binding +relationship: part_of GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0008609 +name: alkylglycerone-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion." [EC:2.5.1.26] +synonym: "1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity" EXACT [EC:2.5.1.26] +synonym: "alkyl DHAP synthetase activity" EXACT [EC:2.5.1.26] +synonym: "alkyl-DHAP" RELATED [EC:2.5.1.26] +synonym: "alkyl-DHAP synthase activity" EXACT [EC:2.5.1.26] +synonym: "alkyldihydroxyacetone phosphate synthetase activity" EXACT [EC:2.5.1.26] +synonym: "alkyldihydroxyacetonephosphate synthase activity" EXACT [EC:2.5.1.26] +synonym: "DHAP-AT" RELATED [EC:2.5.1.26] +synonym: "dihydroxyacetone-phosphate acyltransferase activity" EXACT [EC:2.5.1.26] +xref: EC:2.5.1.26 +xref: MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN +xref: Reactome:R-HSA-390427 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0008610 +name: lipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] +synonym: "lipid anabolism" EXACT [] +synonym: "lipid biosynthesis" EXACT [] +synonym: "lipid formation" EXACT [] +synonym: "lipid synthesis" EXACT [] +synonym: "lipogenesis" EXACT [GOC:sl] +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0008611 +name: ether lipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol." [GOC:ma, ISBN:0198547684, PMID:15337120] +synonym: "ether lipid anabolism" EXACT [] +synonym: "ether lipid biosynthesis" EXACT [] +synonym: "ether lipid formation" EXACT [] +synonym: "ether lipid synthesis" EXACT [] +synonym: "plasmalogen biosynthetic process" NARROW [] +is_a: GO:0046485 ! ether lipid metabolic process +is_a: GO:0046504 ! glycerol ether biosynthetic process +is_a: GO:0097384 ! cellular lipid biosynthetic process + +[Term] +id: GO:0008612 +name: peptidyl-lysine modification to peptidyl-hypusine +namespace: biological_process +alt_id: GO:0046515 +def: "The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine." [GOC:ma, ISBN:0198547684, RESID:AA0116] +synonym: "hypusine anabolism" EXACT [] +synonym: "hypusine anabolism from peptidyl-lysine" EXACT [] +synonym: "hypusine biosynthesis" EXACT [] +synonym: "hypusine biosynthetic process" EXACT [] +synonym: "hypusine biosynthetic process from peptidyl-lysine" EXACT [] +synonym: "hypusine formation" EXACT [] +synonym: "hypusine formation from peptidyl-lysine" EXACT [] +synonym: "hypusine synthesis" EXACT [] +synonym: "hypusine synthesis from peptidyl-lysine" EXACT [] +synonym: "hypusinylation" EXACT [] +synonym: "protein hypusination" EXACT [] +xref: RESID:AA0116 +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0008613 +name: diuretic hormone activity +namespace: molecular_function +def: "The action characteristic of a diuretic hormone, any peptide hormone that, upon receptor binding, regulates water balance and fluid secretion." [GOC:mah, InterPro:IPR003621, PMID:8618894] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0008614 +name: pyridoxine metabolic process +namespace: biological_process +alt_id: GO:0006773 +def: "The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:curators] +synonym: "pyridoxine metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0008615 +name: pyridoxine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds." [GOC:ai] +synonym: "pyridoxine anabolism" EXACT [] +synonym: "pyridoxine biosynthesis" EXACT [] +synonym: "pyridoxine formation" EXACT [] +synonym: "pyridoxine synthesis" EXACT [] +is_a: GO:0008614 ! pyridoxine metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042819 ! vitamin B6 biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0008616 +name: queuosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents." [GOC:go_curators, ISBN:0198506732] +synonym: "queuosine anabolism" EXACT [] +synonym: "queuosine biosynthesis" EXACT [] +synonym: "queuosine formation" EXACT [] +synonym: "queuosine synthesis" EXACT [] +is_a: GO:0042455 ! ribonucleoside biosynthetic process +is_a: GO:0046116 ! queuosine metabolic process +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0008617 +name: guanosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution." [ISBN:0198506732] +synonym: "guanosine metabolism" EXACT [] +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0008618 +name: 7-methylguanosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA." [ISBN:0198506732] +synonym: "7-methylguanosine metabolism" EXACT [] +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0008619 +name: obsolete RHEB small monomeric GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.47, PMID:12893813] +comment: This term was made obsolete because it represents a gene product. +synonym: "RHEB small monomeric GTPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003924 +consider: GO:0001558 +consider: GO:0051726 + +[Term] +id: GO:0008622 +name: epsilon DNA polymerase complex +namespace: cellular_component +def: "A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair." [PMID:15814431, PMID:9745046] +synonym: "DNA polymerase epsilon complex" EXACT [CORUM:420] +is_a: GO:0042575 ! DNA polymerase complex +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0008623 +name: CHRAC +namespace: cellular_component +alt_id: GO:0016588 +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair." [GOC:bf, GOC:krc, PMID:15284901, PMID:16568949, PMID:21810179, PMID:9252192] +synonym: "chromatin accessibility complex" EXACT [] +synonym: "ISW2 complex" NARROW [] +is_a: GO:0031010 ! ISWI-type complex + +[Term] +id: GO:0008625 +name: extrinsic apoptotic signaling pathway via death domain receptors +namespace: biological_process +def: "A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered." [GOC:mah, GOC:mtg_apoptosis] +comment: Gene products that may be annotated to this term include: 1) ligands such as FASL; 2) receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 3) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Examples are TWEAK (TNF12) and FN14 (TNFRSF12A) (UniProt symbols O43508 and Q9NP84) in PMID:21525013. +synonym: "death receptor-mediated apoptosis" NARROW [] +synonym: "induction of apoptosis via death domain receptors" RELATED [] +synonym: "induction of apoptosis via death receptors" EXACT [GOC:mah] +is_a: GO:0097191 ! extrinsic apoptotic signaling pathway + +[Term] +id: GO:0008626 +name: granzyme-mediated apoptotic signaling pathway +namespace: biological_process +def: "A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells." [GOC:mtg_apoptosis, PMID:17158907] +synonym: "apoptotic signaling pathway in response to granzyme" RELATED [] +synonym: "induction of apoptosis by granzyme" RELATED [] +is_a: GO:0097190 ! apoptotic signaling pathway + +[Term] +id: GO:0008627 +name: intrinsic apoptotic signaling pathway in response to osmotic stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, PMID:11454444, PMID:16483738] +synonym: "induction of apoptosis by ionic changes" RELATED [] +is_a: GO:0071470 ! cellular response to osmotic stress +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway + +[Term] +id: GO:0008628 +name: hormone-mediated apoptotic signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered." [GOC:bf, GOC:mtg_apoptosis] +comment: This term is placed under GO:0097190 apoptotic signaling pathway, rather than under one of its more specific children terms, to cover for the variety of apoptosis signaling mechanisms that different hormones may use. +synonym: "apoptotic signaling pathway in response to hormone" RELATED [] +synonym: "induction of apoptosis by hormones" RELATED [] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0097190 ! apoptotic signaling pathway + +[Term] +id: GO:0008630 +name: intrinsic apoptotic signaling pathway in response to DNA damage +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [] +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway + +[Term] +id: GO:0008631 +name: intrinsic apoptotic signaling pathway in response to oxidative stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered." [GOC:ai, GOC:mtg_apoptosis] +synonym: "induction of apoptosis by oxidative stress" RELATED [] +synonym: "oxidative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway +relationship: part_of GO:0036473 ! cell death in response to oxidative stress + +[Term] +id: GO:0008633 +name: obsolete activation of pro-apoptotic gene products +namespace: biological_process +def: "OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form." [GOC:mah, GOC:mtg_apoptosis] +comment: This term was made obsolete because more specific terms were created. Additionally, the meaning of the term is ambiguous (some gene products may be involved in apoptosis, or not, depending on cell type, tissue, condition). +synonym: "activation of pro-apoptotic gene products" EXACT [] +synonym: "induction of pro-apoptotic gene products" RELATED [] +is_obsolete: true + +[Term] +id: GO:0008634 +name: obsolete negative regulation of survival gene product expression +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb] +comment: This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc. +synonym: "down regulation of survival gene product activity" BROAD [] +synonym: "down-regulation of survival gene product activity" BROAD [] +synonym: "downregulation of survival gene product activity" BROAD [] +synonym: "inhibition of survival gene product activity" NARROW [] +synonym: "negative regulation of survival gene product activity" BROAD [GOC:dph, GOC:tb] +synonym: "negative regulation of survival gene product expression" EXACT [] +synonym: "negative regulation of survival gene products" BROAD [] +is_obsolete: true + +[Term] +id: GO:0008635 +name: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c." [GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, Wikipedia:Caspase] +synonym: "activation of caspase activity by cytochrome c" NARROW [] +synonym: "caspase activation via cytochrome c" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006919 ! activation of cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0008636 +name: obsolete activation of caspase activity by protein phosphorylation +namespace: biological_process +def: "OBSOLETE. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group." [GOC:dph, GOC:jl, GOC:tb, PMID:14744432, Wikipedia:Caspase] +comment: This term was made obsolete because it is ill-defined: phosphorylation regulates the activity of caspases, but it doesn't activate them (caspases are only activated upon cleavage). +synonym: "activation of caspase activity by protein amino acid phosphorylation" EXACT [GOC:bf] +synonym: "activation of caspase activity by protein phosphorylation" EXACT [] +synonym: "caspase activation via phosphorylation" EXACT [GOC:dph, GOC:tb] +is_obsolete: true + +[Term] +id: GO:0008637 +name: apoptotic mitochondrial changes +namespace: biological_process +def: "The morphological and physiological alterations undergone by mitochondria during apoptosis." [GOC:mah, GOC:mtg_apoptosis] +comment: This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it. +is_a: GO:0007005 ! mitochondrion organization +relationship: part_of GO:0006915 ! apoptotic process + +[Term] +id: GO:0008638 +name: obsolete protein tagging activity +namespace: molecular_function +def: "OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation." [GOC:jl] +comment: This term was made obsolete because it represents a biological process and a molecular function. +synonym: "protein tagging activity" EXACT [] +is_obsolete: true +consider: GO:0005515 +consider: GO:0006464 +consider: GO:0031386 + +[Term] +id: GO:0008641 +name: ubiquitin-like modifier activating enzyme activity +namespace: molecular_function +alt_id: GO:0008642 +def: "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "small protein activating enzyme activity" NARROW [] +is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14208 xsd:anyURI + +[Term] +id: GO:0008643 +name: carbohydrate transport +namespace: biological_process +alt_id: GO:0006861 +alt_id: GO:0008644 +def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai] +subset: goslim_pir +subset: goslim_yeast +synonym: "sugar transport" NARROW [] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0008645 +name: hexose transmembrane transport +namespace: biological_process +alt_id: GO:0008646 +alt_id: GO:0008647 +alt_id: GO:0035428 +def: "The process in which hexose is transported across a membrane. Hexoses are any aldoses with a chain of six carbon atoms in the molecule." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "hexose membrane transport" RELATED [] +synonym: "hexose transport" RELATED [] +synonym: "high-affinity hexose transport" NARROW [] +synonym: "low-affinity hexose transport" NARROW [] +is_a: GO:0015749 ! monosaccharide transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:27:23Z + +[Term] +id: GO:0008648 +name: obsolete tachykinin +namespace: molecular_function +def: "OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation." [ISBN:0198506732, ISBN:0721662544] +comment: This term was made obsolete because it represents a gene product. +synonym: "tachykinin" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0045987 +consider: GO:0046878 +consider: GO:0097755 + +[Term] +id: GO:0008649 +name: rRNA methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule." [GOC:mah] +is_a: GO:0008173 ! RNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0140102 ! catalytic activity, acting on a rRNA +relationship: part_of GO:0031167 ! rRNA methylation + +[Term] +id: GO:0008650 +name: rRNA (uridine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine." [GOC:mah] +xref: Reactome:R-HSA-6793127 "MRM2 (FTSJ2) methylates uridine-1369 of 16S rRNA yielding 2'-O-methyluridine" +is_a: GO:0016436 ! rRNA (uridine) methyltransferase activity +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity + +[Term] +id: GO:0008651 +name: obsolete actin polymerizing activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a biological process. +synonym: "actin polymerizing activity" EXACT [] +is_obsolete: true +consider: GO:0030041 +consider: GO:0042802 + +[Term] +id: GO:0008652 +name: cellular amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] +synonym: "amino acid biosynthetic process" EXACT [] +synonym: "cellular amino acid anabolism" EXACT [] +synonym: "cellular amino acid biosynthesis" EXACT [] +synonym: "cellular amino acid formation" EXACT [] +synonym: "cellular amino acid synthesis" EXACT [] +xref: Wikipedia:Amino_acid_synthesis +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0008653 +name: lipopolysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [ISBN:0198506732] +synonym: "lipopolysaccharide metabolism" EXACT [] +synonym: "LPS metabolic process" EXACT [] +is_a: GO:0044255 ! cellular lipid metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process +is_a: GO:1903509 ! liposaccharide metabolic process + +[Term] +id: GO:0008654 +name: phospholipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [ISBN:0198506732] +synonym: "phospholipid anabolism" EXACT [] +synonym: "phospholipid biosynthesis" EXACT [] +synonym: "phospholipid formation" EXACT [] +synonym: "phospholipid synthesis" EXACT [] +xref: MetaCyc:LIPASYN-PWY +xref: MetaCyc:PHOSLIPSYN-PWY +xref: MetaCyc:PHOSLIPSYN2-PWY +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0008655 +name: pyrimidine-containing compound salvage +namespace: biological_process +def: "Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis." [GOC:jl] +subset: goslim_pir +synonym: "pyrimidine salvage" RELATED [] +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0008656 +name: cysteine-type endopeptidase activator activity involved in apoptotic process +namespace: molecular_function +def: "Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process." [GOC:mah, GOC:mtg_apoptosis] +comment: Examples of this are 1) granzymes that may bind to initiator caspases and cleave them, and 2) already active caspases, e.g. caspase 9, that cleave effector caspases. +synonym: "caspase activator activity" BROAD [] +xref: Reactome:R-HSA-205117 "p75NTR:NADE promotes caspase2/3 activation" +xref: Reactome:R-HSA-449073 "Caspase-3 cleaves pro-interleukin-16" +is_a: GO:0016505 ! peptidase activator activity involved in apoptotic process +is_a: GO:0043028 ! cysteine-type endopeptidase regulator activity involved in apoptotic process +relationship: part_of GO:0006919 ! activation of cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0008657 +name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:mah] +synonym: "DNA gyrase inhibitor activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042030 ! ATPase inhibitor activity +is_a: GO:0072586 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity +relationship: negatively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +relationship: part_of GO:2000372 ! negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity + +[Term] +id: GO:0008658 +name: penicillin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:ai] +subset: goslim_metagenomics +is_a: GO:0008144 ! drug binding +is_a: GO:0033218 ! amide binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0008659 +name: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.59, GOC:ai, PMID:12368867, RHEA:41892] +synonym: "(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity" EXACT [] +synonym: "(3R)-hydroxymyristoyl-ACP dehydratase activity" EXACT [] +xref: EC:4.2.1.59 +xref: RHEA:41892 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008660 +name: 1-aminocyclopropane-1-carboxylate deaminase activity +namespace: molecular_function +alt_id: GO:0018806 +def: "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+)." [EC:3.5.99.7, RHEA:16933] +comment: Note that this function was formerly EC:4.1.99.4. +synonym: "1-aminocyclopropane carboxylic acid deaminase activity" EXACT [EC:3.5.99.7] +synonym: "1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)" EXACT [EC:3.5.99.7] +synonym: "1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity" EXACT [EC:3.5.99.7] +synonym: "ACC deaminase activity" EXACT [EC:3.5.99.7] +xref: EC:3.5.99.7 +xref: KEGG_REACTION:R00997 +xref: MetaCyc:4.1.99.4-RXN +xref: RHEA:16933 +xref: UM-BBD_reactionID:r0357 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0008661 +name: 1-deoxy-D-xylulose-5-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2)." [EC:2.2.1.7, RHEA:12605] +synonym: "1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity" EXACT [] +synonym: "1-deoxyxylulose-5-phosphate synthase activity" EXACT [] +synonym: "DOXP synthase activity" EXACT [] +synonym: "DXP-synthase activity" EXACT [] +synonym: "pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.7] +xref: EC:2.2.1.7 +xref: KEGG_REACTION:R05636 +xref: MetaCyc:DXS-RXN +xref: RHEA:12605 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0008662 +name: 1-phosphofructokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate." [EC:2.7.1.56] +synonym: "1-phosphofructokinase (phosphorylating)" EXACT [EC:2.7.1.56] +synonym: "ATP:D-fructose-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.56] +synonym: "D-fructose-1-phosphate kinase activity" EXACT [EC:2.7.1.56] +synonym: "fructose 1-phosphate kinase activity" EXACT [EC:2.7.1.56] +synonym: "fructose-1-phosphate kinase activity" EXACT [EC:2.7.1.56] +synonym: "phosphofructokinase 1" RELATED [EC:2.7.1.56] +xref: EC:2.7.1.56 +xref: MetaCyc:1PFRUCTPHOSN-RXN +xref: RHEA:14213 +is_a: GO:0008443 ! phosphofructokinase activity + +[Term] +id: GO:0008663 +name: 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate." [EC:3.1.4.16] +synonym: "2',3 '-cyclic AMP phosphodiesterase activity" EXACT [EC:3.1.4.16] +synonym: "2',3'-cyclic AMP 2'-phosphohydrolase activity" EXACT [EC:3.1.4.16] +synonym: "2',3'-cyclic nucleoside monophosphate phosphodiesterase" BROAD [EC:3.1.4.16] +synonym: "2',3'-cyclic nucleotidase activity" EXACT [EC:3.1.4.16] +synonym: "2',3'-cyclic nucleotide phosphohydrolase" BROAD [EC:3.1.4.16] +synonym: "2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity" EXACT [EC:3.1.4.16] +synonym: "2':3'-cyclic phosphodiesterase activity" EXACT [EC:3.1.4.16] +synonym: "cyclic 2',3'-nucleotide 2'-phosphodiesterase activity" EXACT [EC:3.1.4.16] +synonym: "cyclic 2',3'-nucleotide phosphodiesterase" BROAD [EC:3.1.4.16] +synonym: "cyclic phosphodiesterase:3'-nucleotidase activity" EXACT [EC:3.1.4.16] +synonym: "nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity" EXACT [EC:3.1.4.16] +synonym: "ribonucleoside 2',3'-cyclic phosphate diesterase activity" EXACT [EC:3.1.4.16] +xref: EC:3.1.4.16 +xref: MetaCyc:CYCPHOSDIESTER-RXN +is_a: GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0008664 +name: 2'-5'-RNA ligase activity +namespace: molecular_function +def: "Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another." [GOC:mah, PMID:8940112] +synonym: "2'-5' RNA ligase activity" EXACT [] +is_a: GO:0008452 ! RNA ligase activity + +[Term] +id: GO:0008666 +name: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA." [EC:2.3.1.117, RHEA:17325] +synonym: "succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity" EXACT [EC:2.3.1.117] +synonym: "succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity" EXACT [EC:2.3.1.117] +synonym: "succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity" EXACT [EC:2.3.1.117] +synonym: "tetrahydrodipicolinate N-succinyltransferase activity" EXACT [EC:2.3.1.117] +synonym: "tetrahydrodipicolinate succinylase activity" EXACT [EC:2.3.1.117] +synonym: "tetrahydrodipicolinate succinyltransferase activity" EXACT [EC:2.3.1.117] +synonym: "tetrahydropicolinate succinylase activity" EXACT [EC:2.3.1.117] +synonym: "THDP N-succinyltransferase activity" EXACT [PMID:19394346] +xref: EC:2.3.1.117 +xref: KEGG_REACTION:R04365 +xref: MetaCyc:TETHYDPICSUCC-RXN +xref: RHEA:17325 +is_a: GO:0016749 ! N-succinyltransferase activity + +[Term] +id: GO:0008667 +name: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH." [EC:1.3.1.28, RHEA:23824] +synonym: "2,3-DHB dehydrogenase activity" EXACT [EC:1.3.1.28] +synonym: "2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.28] +xref: EC:1.3.1.28 +xref: KEGG_REACTION:R01505 +xref: MetaCyc:DHBDEHYD-RXN +xref: RHEA:23824 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008668 +name: (2,3-dihydroxybenzoyl)adenylate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate." [EC:2.7.7.58, RHEA:20229] +synonym: "2,3-dihydroxybenzoate-AMP ligase activity" EXACT [] +synonym: "ATP:2,3-dihydroxybenzoate adenylyltransferase activity" EXACT [EC:2.7.7.58] +xref: EC:2.7.7.58 +xref: KEGG_REACTION:R01504 +xref: MetaCyc:DHBAMPLIG-RXN +xref: RHEA:20229 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0008670 +name: 2,4-dienoyl-CoA reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+." [EC:1.3.1.34] +synonym: "4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.34] +synonym: "4-enoyl-CoA reductase (NADPH) activity" EXACT [EC:1.3.1.34] +synonym: "4-enoyl-CoA reductase (NADPH2)" EXACT [EC:1.3.1.34] +synonym: "4-enoyl-CoA reductase activity" EXACT [EC:1.3.1.34] +synonym: "trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity" EXACT [EC:1.3.1.34] +xref: EC:1.3.1.34 +xref: MetaCyc:DIENOYLCOAREDUCT-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008671 +name: 2-dehydro-3-deoxygalactonokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+)." [EC:2.7.1.58, RHEA:16525] +synonym: "2-keto-3-deoxy-galactonokinase activity" EXACT [EC:2.7.1.58] +synonym: "2-keto-3-deoxygalactonate kinase (phosphorylating)" EXACT [EC:2.7.1.58] +synonym: "2-keto-3-deoxygalactonokinase activity" EXACT [EC:2.7.1.58] +synonym: "2-oxo-3-deoxygalactonate kinase activity" EXACT [EC:2.7.1.58] +synonym: "ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity" EXACT [EC:2.7.1.58] +xref: EC:2.7.1.58 +xref: KEGG_REACTION:R03387 +xref: MetaCyc:DEHYDDEOXGALACTKIN-RXN +xref: RHEA:16525 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008672 +name: 2-dehydro-3-deoxyglucarate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde." [EC:4.1.2.20] +synonym: "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.20] +synonym: "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity" EXACT [EC:4.1.2.20] +synonym: "2-keto-3-deoxyglucarate aldolase activity" EXACT [EC:4.1.2.20] +synonym: "alpha-keto-beta-deoxy-D-glucarate aldolase activity" EXACT [EC:4.1.2.20] +xref: EC:4.1.2.20 +xref: MetaCyc:KDGALDOL-RXN +xref: RHEA:10268 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008673 +name: 2-dehydro-3-deoxygluconokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+)." [EC:2.7.1.45, RHEA:14797] +synonym: "2-keto-3-deoxy-D-gluconic acid kinase activity" EXACT [EC:2.7.1.45] +synonym: "2-keto-3-deoxygluconate kinase activity" EXACT [EC:2.7.1.45] +synonym: "2-keto-3-deoxygluconokinase (phosphorylating)" EXACT [EC:2.7.1.45] +synonym: "2-keto-3-deoxygluconokinase activity" EXACT [EC:2.7.1.45] +synonym: "3-deoxy-2-oxo-D-gluconate kinase activity" EXACT [EC:2.7.1.45] +synonym: "ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.45] +synonym: "KDG kinase activity" EXACT [EC:2.7.1.45] +synonym: "ketodeoxygluconokinase activity" EXACT [EC:2.7.1.45] +xref: EC:2.7.1.45 +xref: KEGG_REACTION:R01541 +xref: MetaCyc:DEOXYGLUCONOKIN-RXN +xref: RHEA:14797 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008674 +name: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate." [EC:4.1.2.21, RHEA:24464] +synonym: "(KDPGal)aldolase activity" EXACT [EC:4.1.2.21] +synonym: "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)" EXACT [EC:4.1.2.21] +synonym: "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.21] +synonym: "2-dehydro-3-deoxyphosphogalactonate aldolase activity" EXACT [] +synonym: "2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity" EXACT [EC:4.1.2.21] +synonym: "2-keto-3-deoxy-6-phosphogalactonic aldolase activity" EXACT [EC:4.1.2.21] +synonym: "2-oxo-3-deoxygalactonate 6-phosphate aldolase activity" EXACT [EC:4.1.2.21] +synonym: "6-phospho-2-dehydro-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] +synonym: "6-phospho-2-keto-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] +synonym: "phospho-2-keto-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] +synonym: "phospho-2-keto-3-deoxygalactonic aldolase activity" EXACT [EC:4.1.2.21] +xref: EC:4.1.2.21 +xref: KEGG_REACTION:R01064 +xref: MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN +xref: RHEA:24464 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008675 +name: 2-dehydro-3-deoxy-phosphogluconate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.14] +synonym: "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)" EXACT [EC:4.1.2.14] +synonym: "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.14] +synonym: "2-keto-3-deoxy-6-phosphogluconate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "2-keto-3-deoxy-6-phosphogluconic aldolase activity" EXACT [EC:4.1.2.14] +synonym: "2-keto-3-deoxygluconate-6-P-aldolase activity" EXACT [EC:4.1.2.14] +synonym: "2-keto-3-deoxygluconate-6-phosphate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "2-oxo-3-deoxy-6-phosphogluconate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "6-phospho-2-keto-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "KDPG aldolase activity" EXACT [EC:4.1.2.14] +synonym: "KDPG-aldolase activity" EXACT [EC:4.1.2.14] +synonym: "ODPG aldolase activity" EXACT [EC:4.1.2.14] +synonym: "phospho-2-dehydro-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "phospho-2-keto-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] +synonym: "phospho-2-keto-3-deoxygluconic aldolase activity" EXACT [EC:4.1.2.14] +xref: EC:4.1.2.14 +xref: MetaCyc:KDPGALDOL-RXN +xref: RHEA:17089 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008676 +name: 3-deoxy-8-phosphooctulonate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate." [EC:2.5.1.55, RHEA:14053] +comment: Note that this function was formerly EC:4.1.2.16. +synonym: "2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.55] +synonym: "2-dehydro-3-deoxy-phosphooctonate aldolase activity" EXACT [EC:2.5.1.55] +synonym: "2-dehydro-3-deoxyphosphooctonate aldolase activity" EXACT [] +synonym: "2-keto-3-deoxy-8-phosphooctonic synthetase activity" EXACT [EC:2.5.1.55] +synonym: "3-deoxy-D-manno-octulosonate-8-phosphate synthase activity" EXACT [EC:2.5.1.55] +synonym: "3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity" EXACT [EC:2.5.1.55] +synonym: "3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity" EXACT [EC:2.5.1.55] +synonym: "3-deoxyoctulosonic 8-phosphate synthetase activity" EXACT [EC:2.5.1.55] +synonym: "KDO-8-P synthase activity" EXACT [EC:2.5.1.55] +synonym: "KDO-8-phosphate synthetase activity" EXACT [EC:2.5.1.55] +synonym: "KDOP synthase activity" EXACT [EC:2.5.1.55] +synonym: "phospho-2-keto-3-deoxyoctonate aldolase activity" EXACT [EC:2.5.1.55] +synonym: "phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.55] +xref: EC:2.5.1.55 +xref: KEGG_REACTION:R03254 +xref: MetaCyc:KDO-8PSYNTH-RXN +xref: RHEA:14053 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0008677 +name: 2-dehydropantoate 2-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH." [EC:1.1.1.169, RHEA:16233] +synonym: "(R)-pantoate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.169] +synonym: "2-ketopantoate reductase activity" EXACT [EC:1.1.1.169] +synonym: "2-ketopantoic acid reductase activity" EXACT [EC:1.1.1.169] +synonym: "2-oxopantoate reductase activity" EXACT [EC:1.1.1.169] +synonym: "ketopantoate reductase activity" EXACT [EC:1.1.1.169] +synonym: "ketopantoic acid reductase activity" EXACT [EC:1.1.1.169] +synonym: "KPA reductase activity" EXACT [EC:1.1.1.169] +xref: EC:1.1.1.169 +xref: KEGG_REACTION:R02472 +xref: MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN +xref: RHEA:16233 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008678 +name: 2-deoxy-D-gluconate 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+." [EC:1.1.1.125] +synonym: "2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.125] +synonym: "2-deoxygluconate dehydrogenase activity" EXACT [EC:1.1.1.125] +synonym: "2-keto-3-deoxygluconate oxidoreductase activity" EXACT [EC:1.1.1.125] +xref: EC:1.1.1.125 +xref: MetaCyc:KDUD-RXN +xref: RHEA:12160 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008679 +name: 2-hydroxy-3-oxopropionate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+." [EC:1.1.1.60] +synonym: "(R)-glycerate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.60] +synonym: "tartronate semialdehyde reductase (NADPH) activity" EXACT [EC:1.1.1.60] +xref: EC:1.1.1.60 +xref: MetaCyc:TSA-REDUCT-RXN +xref: RHEA:18841 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008681 +name: 2-octaprenyl-6-methoxyphenol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O." [MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN] +xref: EC:1.14.14 +xref: MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN +xref: RHEA:29407 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0008682 +name: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone." [MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN] +synonym: "demethoxy-ubiquinone hydroxylase" RELATED [GOC:vw] +synonym: "demethoxyubiquinone monooxygenase" RELATED [GOC:vw] +xref: MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0008683 +name: 2-oxoglutarate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde." [EC:4.1.1.71, RHEA:10524] +synonym: "2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)" EXACT [EC:4.1.1.71] +synonym: "2-oxoglutarate carboxy-lyase activity" EXACT [EC:4.1.1.71] +synonym: "alpha-ketoglutarate decarboxylase activity" EXACT [EC:4.1.1.71] +synonym: "alpha-ketoglutaric decarboxylase activity" EXACT [EC:4.1.1.71] +synonym: "pre-2-oxoglutarate decarboxylase activity" EXACT [EC:4.1.1.71] +xref: EC:4.1.1.71 +xref: KEGG_REACTION:R00272 +xref: MetaCyc:RXN-7774 +xref: RHEA:10524 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008684 +name: 2-oxopent-4-enoate hydratase activity +namespace: molecular_function +alt_id: GO:0018821 +def: "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O." [EC:4.2.1.80] +synonym: "2-keto-4-pentenoate (vinylpyruvate)hydratase activity" EXACT [EC:4.2.1.80] +synonym: "2-keto-4-pentenoate hydratase activity" EXACT [EC:4.2.1.80] +synonym: "4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)" EXACT [EC:4.2.1.80] +synonym: "4-hydroxy-2-oxopentanoate hydro-lyase activity" EXACT [EC:4.2.1.80] +synonym: "OEH activity" EXACT [EC:4.2.1.80] +xref: EC:4.2.1.80 +xref: MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN +xref: RHEA:22580 +xref: UM-BBD_enzymeID:e0078 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008685 +name: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP." [EC:4.6.1.12, RHEA:23864] +synonym: "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)" EXACT [EC:4.6.1.12] +synonym: "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)" EXACT [EC:4.6.1.12] +synonym: "MECDP-synthase activity" EXACT [EC:4.6.1.12] +synonym: "MECP synthase activity" EXACT [] +xref: EC:4.6.1.12 +xref: KEGG_REACTION:R05637 +xref: MetaCyc:RXN0-302 +xref: RHEA:23864 +is_a: GO:0016849 ! phosphorus-oxygen lyase activity + +[Term] +id: GO:0008686 +name: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)." [EC:4.1.99.12, RHEA:18457] +xref: EC:4.1.99.12 +xref: KEGG_REACTION:R07281 +xref: MetaCyc:DIOHBUTANONEPSYN-RXN +xref: RHEA:18457 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0008687 +name: 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+)." [EC:1.13.11.15, RHEA:15633] +synonym: "3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.15] +synonym: "3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity" EXACT [EC:1.13.11.15] +synonym: "homoprotocatechuate 2,3-dioxygenase activity" EXACT [EC:1.13.11.15] +synonym: "HPC dioxygenase activity" EXACT [EC:1.13.11.15] +xref: EC:1.13.11.15 +xref: KEGG_REACTION:R03303 +xref: MetaCyc:1.13.11.15-RXN +xref: RHEA:15633 +xref: UM-BBD_reactionID:r0364 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0008688 +name: 3-(3-hydroxyphenyl)propionate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O." [MetaCyc:MHPHYDROXY-RXN] +xref: EC:1.14.13 +xref: KEGG_REACTION:R06786 +xref: MetaCyc:MHPHYDROXY-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0008689 +name: 3-demethylubiquinone-9 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9." [GOC:dph] +synonym: "5-demethylubiquinone-9 methyltransferase activity" EXACT [EC:2.1.1.64] +synonym: "OMHMB-methyltransferase activity" EXACT [EC:2.1.1.64] +synonym: "S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity" EXACT [EC:2.1.1.64] +synonym: "S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity" EXACT [EC:2.1.1.64] +xref: EC:2.1.1.64 +xref: MetaCyc:DHHB-METHYLTRANSFER-RXN +xref: RHEA:17049 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0061542 ! 3-demethylubiquinol-n 3-O-methyltransferase activity + +[Term] +id: GO:0008690 +name: 3-deoxy-manno-octulosonate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate." [EC:2.7.7.38] +synonym: "2-keto-3-deoxyoctonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] +synonym: "3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] +synonym: "CMP-2-keto-3-deoxyoctulosonic acid synthetase activity" EXACT [EC:2.7.7.38] +synonym: "CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity" EXACT [EC:2.7.7.38] +synonym: "CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity" EXACT [EC:2.7.7.38] +synonym: "CMP-3-deoxy-D-manno-octulosonate synthetase activity" EXACT [EC:2.7.7.38] +synonym: "CMP-KDO synthetase activity" EXACT [EC:2.7.7.38] +synonym: "CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] +synonym: "CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity" EXACT [] +synonym: "CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] +synonym: "cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity" EXACT [EC:2.7.7.38] +xref: EC:2.7.7.38 +xref: MetaCyc:CPM-KDOSYNTH-RXN +xref: RHEA:23448 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0008691 +name: 3-hydroxybutyryl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+." [EC:1.1.1.157] +synonym: "(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.157] +synonym: "beta-hydroxybutyryl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.157] +synonym: "beta-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] +synonym: "BHBD activity" EXACT [EC:1.1.1.157] +synonym: "dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.157] +synonym: "L(+)-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] +synonym: "L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] +xref: EC:1.1.1.157 +xref: MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN +xref: RHEA:16197 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008692 +name: 3-hydroxybutyryl-CoA epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA." [EC:5.1.2.3] +synonym: "3-hydroxyacyl-CoA epimerase activity" EXACT [EC:5.1.2.3] +synonym: "3-hydroxybutanoyl-CoA 3-epimerase activity" EXACT [EC:5.1.2.3] +synonym: "3-hydroxybutyryl coenzyme A epimerase activity" EXACT [EC:5.1.2.3] +xref: EC:5.1.2.3 +xref: MetaCyc:OHBUTYRYL-COA-EPIM-RXN +xref: RHEA:21760 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0008693 +name: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.59, PMID:8910376, RHEA:41860] +synonym: "(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.59] +synonym: "3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity" EXACT [] +synonym: "3-hydroxydecanoyl-ACP dehydratase activity" EXACT [] +synonym: "3-hydroxydecanoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "3-hydroxydecanoyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxyacyl-ACP dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxyacyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxydecanoate dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxydecanoyl thioester dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxydecanoyl thiol ester dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "FabA" RELATED [] +synonym: "HDDase activity" EXACT [EC:4.2.1.59] +xref: EC:4.2.1.59 +xref: RHEA:41860 +is_a: GO:0019171 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity + +[Term] +id: GO:0008694 +name: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity +namespace: molecular_function +alt_id: GO:0019167 +def: "Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2." [MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN] +synonym: "3-octaprenyl-4-hydroxybenzoate decarboxylase activity" EXACT [] +synonym: "3-polyprenyl 4-hydroxybenzoate decarboxylase activity" EXACT [] +synonym: "3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity" EXACT [] +synonym: "polyprenyl p-hydroxybenzoate decarboxylase activity" EXACT [] +synonym: "PPHB decarboxylase activity" EXACT [] +synonym: "UbiD" RELATED [] +synonym: "UbiX" RELATED [] +xref: EC:4.1.1.98 +xref: MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN +xref: RHEA:27778 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008695 +name: 3-phenylpropionate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol." [UM-BBD_enzymeID:e0307] +synonym: "3-phenylpropanoate dioxygenase activity" EXACT [EC:1.14.12.19] +synonym: "3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity" EXACT [EC:1.14.12.19] +synonym: "Hca dioxygenase activity" EXACT [EC:1.14.12.19] +synonym: "HcaA1A2CD" RELATED [EC:1.14.12.19] +xref: EC:1.14.12.19 +xref: MetaCyc:HCAMULTI-RXN +xref: RHEA:20357 +xref: UM-BBD_enzymeID:e0307 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0008696 +name: 4-amino-4-deoxychorismate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate." [EC:4.1.3.38, RHEA:16201] +comment: Note that the name 'para-amino benzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate. +synonym: "4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)" EXACT [EC:4.1.3.38] +synonym: "4-amino-4-deoxychorismate pyruvate-lyase activity" EXACT [EC:4.1.3.38] +synonym: "ADC lyase activity" EXACT [EC:4.1.3.38] +synonym: "aminodeoxychorismate lyase activity" EXACT [] +synonym: "enzyme X activity" RELATED [EC:4.1.3.38] +synonym: "p-aminobenzoate synthetase" RELATED [] +synonym: "para-aminobenzoic acid (PABA) synthase" RELATED [] +synonym: "para-aminobenzoic acid synthase" RELATED [] +xref: EC:4.1.3.38 +xref: KEGG_REACTION:R05553 +xref: MetaCyc:ADCLY-RXN +xref: RHEA:16201 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008697 +name: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate." [EC:5.3.1.17, RHEA:23896] +synonym: "4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.17] +synonym: "4-deoxy-L-threo-5-hexulose uronate isomerase activity" EXACT [EC:5.3.1.17] +synonym: "5-keto-4-deoxyuronate isomerase activity" EXACT [EC:5.3.1.17] +xref: EC:5.3.1.17 +xref: KEGG_REACTION:R04383 +xref: MetaCyc:5.3.1.17-RXN +xref: RHEA:23896 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008700 +name: 4-hydroxy-2-oxoglutarate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate." [EC:4.1.3.16] +synonym: "2-keto-4-hydroxybutyrate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "2-keto-4-hydroxyglutarate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "2-keto-4-hydroxyglutaric aldolase activity" EXACT [EC:4.1.3.16] +synonym: "2-oxo-4-hydroxyglutarate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "2-oxo-4-hydroxyglutaric aldolase activity" EXACT [EC:4.1.3.16] +synonym: "4-hydroxy-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "4-hydroxy-2-ketoglutaric aldolase activity" EXACT [EC:4.1.3.16] +synonym: "4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)" EXACT [EC:4.1.3.16] +synonym: "4-hydroxy-2-oxoglutarate glyoxylate-lyase activity" EXACT [EC:4.1.3.16] +synonym: "DL-4-hydroxy-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "hydroxyketoglutarate aldolase activity" EXACT [EC:4.1.3.16] +synonym: "hydroxyketoglutaric aldolase activity" EXACT [EC:4.1.3.16] +synonym: "KHG-aldolase activity" EXACT [EC:4.1.3.16] +xref: EC:4.1.3.16 +xref: MetaCyc:4OH2OXOGLUTARALDOL-RXN +xref: Reactome:R-HSA-6784423 "HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate" +xref: RHEA:18169 +is_a: GO:0016832 ! aldehyde-lyase activity +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008701 +name: 4-hydroxy-2-oxovalerate aldolase activity +namespace: molecular_function +alt_id: GO:0018804 +def: "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate." [EC:4.1.3.39, RHEA:22624] +synonym: "4-hydroxy-2-ketovalerate aldolase activity" EXACT [EC:4.1.3.39] +synonym: "4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity" EXACT [EC:4.1.3.39] +synonym: "4-hydroxy-2-oxopentanoate pyruvate-lyase activity" EXACT [EC:4.1.3.39] +synonym: "4-hydroxy-2-oxovalerate pyruvate-lyase activity" EXACT [EC:4.1.3.39] +synonym: "DmpG" RELATED [EC:4.1.3.39] +synonym: "HOA" RELATED [EC:4.1.3.39] +xref: EC:4.1.3.39 +xref: KEGG_REACTION:R00750 +xref: MetaCyc:MHPELY-RXN +xref: RHEA:22624 +xref: UM-BBD_enzymeID:e0077 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008703 +name: 5-amino-6-(5-phosphoribosylamino)uracil reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH." [EC:1.1.1.193, RHEA:17845] +synonym: "5-amino-6-(5'-phosphoribosylamino)uracil reductase activity" EXACT [] +synonym: "5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity" EXACT [EC:1.1.1.193] +synonym: "aminodioxyphosphoribosylaminopyrimidine reductase activity" EXACT [EC:1.1.1.193] +xref: EC:1.1.1.193 +xref: KEGG_REACTION:R03458 +xref: MetaCyc:RIBOFLAVINSYNREDUC-RXN +xref: RHEA:17845 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008704 +name: 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity +namespace: molecular_function +alt_id: GO:0018843 +def: "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate." [EC:5.3.3.10] +synonym: "2-hydroxyhepta-2,4-diene-1,7-dioate isomerase" RELATED [] +synonym: "5-carboxymethyl-2-hydroxymuconate D-isomerase activity" EXACT [] +synonym: "5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity" EXACT [EC:5.3.3.10] +synonym: "5-carboxymethyl-2-hydroxymuconic acid isomerase activity" EXACT [EC:5.3.3.10] +synonym: "CHM isomerase activity" EXACT [EC:5.3.3.10] +synonym: "HHDD isomerase activity" EXACT [] +synonym: "hpaG-1" RELATED [] +synonym: "hpaG1" RELATED [] +xref: EC:5.3.3.10 +xref: MetaCyc:5.3.3.10-RXN +xref: RHEA:18813 +xref: UM-BBD_reactionID:r0366 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0008705 +name: methionine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine." [EC:2.1.1.13, RHEA:11172] +synonym: "5-methyltetrahydrofolate--homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "5-methyltetrahydrofolate--homocysteine transmethylase activity" EXACT [EC:2.1.1.13] +synonym: "5-methyltetrahydrofolate-homocysteine S-methyltransferase activity" EXACT [] +synonym: "5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "cobalamin-dependent methionine synthase activity" EXACT [EC:2.1.1.13] +synonym: "MetH" RELATED [EC:2.1.1.13] +synonym: "methionine synthase (cobalamin-dependent) activity" EXACT [EC:2.1.1.13] +synonym: "methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N(5)-methyltetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity" EXACT [EC:2.1.1.13] +synonym: "N-methyltetrahydrofolate:L-homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N5-methyltetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity" EXACT [EC:2.1.1.13] +synonym: "tetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "tetrahydropteroylglutamate methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "tetrahydropteroylglutamic methyltransferase activity" EXACT [EC:2.1.1.13] +synonym: "vitamin B12 methyltransferase activity" EXACT [EC:2.1.1.13] +xref: EC:2.1.1.13 +xref: KEGG_REACTION:R00946 +xref: MetaCyc:HOMOCYSMETB12-RXN +xref: Reactome:R-HSA-174374 "MTR transfers CH3 from MeCbl to HCYS" +xref: Reactome:R-HSA-3149539 "MTR transfers CH3 group from MTHF to cob(I)alamin" +xref: RHEA:11172 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0042084 ! 5-methyltetrahydrofolate-dependent methyltransferase activity +relationship: part_of GO:0009086 ! methionine biosynthetic process + +[Term] +id: GO:0008706 +name: 6-phospho-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose." [EC:3.2.1.86] +synonym: "6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity" EXACT [EC:3.2.1.86] +synonym: "phospho-beta-glucosidase A" RELATED [EC:3.2.1.86] +synonym: "phospho-beta-glucosidase activity" EXACT [EC:3.2.1.86] +synonym: "phosphocellobiase activity" EXACT [EC:3.2.1.86] +xref: EC:3.2.1.86 +xref: MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN +xref: RHEA:10772 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0008707 +name: 4-phytase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate." [EC:3.1.3.26] +synonym: "6-phytase (name based on 1L-numbering system and not 1D-numbering)" BROAD [EC:3.1.3.26] +synonym: "6-phytase activity" EXACT [] +synonym: "myo-inositol-hexakisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.26] +synonym: "phytase activity" BROAD [EC:3.1.3.26] +synonym: "phytate 6-phosphatase activity" EXACT [EC:3.1.3.26] +xref: EC:3.1.3.26 +xref: MetaCyc:6-PHYT-RXN +xref: RHEA:20960 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0008709 +name: cholate 7-alpha-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH." [EC:1.1.1.159, RHEA:19409] +synonym: "7-alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.159] +synonym: "7alpha-HSDH" RELATED [EC:1.1.1.159] +synonym: "7alpha-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.159] +synonym: "7alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.159] +synonym: "7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity" BROAD [EC:1.1.1.159] +xref: EC:1.1.1.159 +xref: KEGG_REACTION:R02792 +xref: MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN +xref: RHEA:19409 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008710 +name: 8-amino-7-oxononanoate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA." [EC:2.3.1.47, RHEA:20712] +synonym: "6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)" EXACT [EC:2.3.1.47] +synonym: "7-KAP synthetase activity" EXACT [EC:2.3.1.47] +synonym: "7-keto-8-amino-pelargonic acid synthetase activity" EXACT [EC:2.3.1.47] +synonym: "7-keto-8-aminopelargonic acid synthetase activity" EXACT [EC:2.3.1.47] +synonym: "7-keto-8-aminopelargonic synthetase activity" EXACT [EC:2.3.1.47] +synonym: "8-amino-7-ketopelargonate synthase activity" EXACT [EC:2.3.1.47] +synonym: "8-amino-7-oxopelargonate synthase activity" EXACT [EC:2.3.1.47] +synonym: "AONS activity" EXACT [EC:2.3.1.47] +xref: EC:2.3.1.47 +xref: KEGG_REACTION:R03210 +xref: MetaCyc:7KAPSYN-RXN +xref: RHEA:20712 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0008711 +name: obsolete ADP-L-glycero-D-manno-heptose synthase activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:curators] +comment: This term was made obsolete because it represents a bifunctional gene product (e.g. E. coli RfaE). +synonym: "ADP-L-glycero-D-manno-heptose synthase activity" EXACT [] +is_obsolete: true +consider: GO:0033785 +consider: GO:0033786 + +[Term] +id: GO:0008712 +name: ADP-glyceromanno-heptose 6-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose." [EC:5.1.3.20, RHEA:17577] +synonym: "ADP-L-glycero-D-manno-heptose 6-epimerase activity" EXACT [EC:5.1.3.20] +synonym: "ADPglyceromanno-heptose 6-epimerase activity" EXACT [EC:5.1.3.20] +xref: EC:5.1.3.20 +xref: KEGG_REACTION:R05176 +xref: MetaCyc:5.1.3.20-RXN +xref: RHEA:17577 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0008713 +name: ADP-heptose-lipopolysaccharide heptosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+." [MetaCyc:RXN0-5061] +synonym: "ADP-heptose:LPS heptosyltransferase activity" EXACT [MetaCyc:LIPA-CORESYN-PWY] +xref: MetaCyc:RXN0-5061 +is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity + +[Term] +id: GO:0008714 +name: AMP nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine." [EC:3.2.2.4, RHEA:20129] +synonym: "adenosine monophosphate nucleosidase activity" EXACT [EC:3.2.2.4] +synonym: "adenylate nucleosidase activity" EXACT [EC:3.2.2.4] +synonym: "AMP phosphoribohydrolase activity" EXACT [EC:3.2.2.4] +xref: EC:3.2.2.4 +xref: KEGG_REACTION:R00182 +xref: MetaCyc:AMP-NUCLEOSID-RXN +xref: RHEA:20129 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0008715 +name: CDP-diacylglycerol diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+)." [EC:3.6.1.26, RHEA:15221] +synonym: "CDP diacylglycerol hydrolase activity" EXACT [EC:3.6.1.26] +synonym: "CDP-diacylglycerol phosphatidylhydrolase activity" EXACT [EC:3.6.1.26] +synonym: "CDP-diacylglycerol pyrophosphatase activity" EXACT [] +synonym: "cytidine diphosphodiacylglycerol pyrophosphatase activity" EXACT [EC:3.6.1.26] +xref: EC:3.6.1.26 +xref: KEGG_REACTION:R01797 +xref: MetaCyc:CDPDIGLYPYPHOSPHA-RXN +xref: RHEA:15221 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0008716 +name: D-alanine-D-alanine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate." [EC:6.3.2.4, RHEA:11224] +synonym: "alanine:alanine ligase (ADP-forming) activity" EXACT [EC:6.3.2.4] +synonym: "alanylalanine synthetase activity" EXACT [EC:6.3.2.4] +synonym: "D-Ala-D-Ala synthetase activity" EXACT [EC:6.3.2.4] +synonym: "D-alanine:D-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.4] +synonym: "D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.4] +synonym: "D-alanylalanine synthetase activity" EXACT [EC:6.3.2.4] +xref: EC:6.3.2.4 +xref: KEGG_REACTION:R01150 +xref: MetaCyc:DALADALALIG-RXN +xref: RHEA:11224 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0008717 +name: obsolete D-alanyl-D-alanine endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "D-alanyl-D-alanine endopeptidase activity" EXACT [] +synonym: "penicillin-binding protein 7" NARROW [] +synonym: "penicillin-binding protein 8" NARROW [] +xref: EC:3.4.99 +is_obsolete: true +replaced_by: GO:0004175 + +[Term] +id: GO:0008718 +name: D-amino-acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor." [RHEA:18125] +synonym: "D-amino-acid:(acceptor) oxidoreductase (deaminating)" EXACT [] +synonym: "D-amino-acid:acceptor oxidoreductase (deaminating)" EXACT [] +xref: MetaCyc:DAADEHYDROG-RXN +xref: RHEA:18125 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0008719 +name: dihydroneopterin triphosphate 2'-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate." [MetaCyc:H2NTPEPIM-RXN] +synonym: "D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity" EXACT [] +xref: EC:5.1.99.7 +xref: MetaCyc:H2NTPEPIM-RXN +xref: RHEA:28346 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0008720 +name: D-lactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate." [EC:1.1.1.28, RHEA:16369] +synonym: "D-lactic acid dehydrogenase activity" EXACT [EC:1.1.1.28] +synonym: "D-lactic dehydrogenase activity" EXACT [EC:1.1.1.28] +xref: EC:1.1.1.28 +xref: KEGG_REACTION:R00704 +xref: MetaCyc:DLACTDEHYDROGNAD-RXN +xref: RHEA:16369 +is_a: GO:0004457 ! lactate dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008721 +name: D-serine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-serine = pyruvate + NH3." [EC:4.3.1.18] +comment: Note that this function was formerly EC:4.3.1.14. +synonym: "D-hydroxy amino acid dehydratase activity" BROAD [EC:4.3.1.18] +synonym: "D-hydroxyaminoacid dehydratase activity" EXACT [EC:4.3.1.18] +synonym: "D-serine ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.18] +synonym: "D-serine deaminase activity" EXACT [EC:4.3.1.18] +synonym: "D-serine dehydrase activity" EXACT [EC:4.3.1.18] +synonym: "D-serine dehydratase (deaminating) activity" EXACT [EC:4.3.1.18] +synonym: "D-serine dehydratase activity" EXACT [EC:4.3.1.18] +synonym: "D-serine hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.18] +synonym: "D-serine hydrolase activity" EXACT [EC:4.3.1.18] +xref: EC:4.3.1.18 +xref: MetaCyc:DSERDEAM-RXN +xref: Reactome:R-HSA-9014741 "SRR dimer:PXLP deaminates D-Ser" +xref: Reactome:R-HSA-9034539 "SRR dimer:PXLP deaminates L-Ser" +xref: RHEA:13977 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0008724 +name: obsolete DNA topoisomerase IV activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo." [EC:5.99.1.-, PMID:11274059] +comment: This term was made obsolete because it represents a gene product. +synonym: "DNA topoisomerase IV activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003918 + +[Term] +id: GO:0008725 +name: DNA-3-methyladenine glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site." [EC:3.2.2.20, GOC:elh, PMID:10872450, PMID:9224623] +synonym: "3-methyladenine DNA glycosylase I" RELATED [EC:3.2.2.20] +synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.20] +synonym: "deoxyribonucleate 3-methyladenine glycosidase I" RELATED [EC:3.2.2.20] +synonym: "DNA glycosidase I activity" RELATED [EC:3.2.2.20] +synonym: "DNA-3-methyladenine glycosidase I activity" EXACT [EC:3.2.2.20] +synonym: "DNA-3-methyladenine glycosylase I activity" EXACT [] +xref: EC:3.2.2.20 +xref: EC:3.2.2.21 +xref: MetaCyc:3.2.2.20-RXN +xref: MetaCyc:3.2.2.21-RXN +is_a: GO:0043733 ! DNA-3-methylbase glycosylase activity + +[Term] +id: GO:0008726 +name: alkanesulfonate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN." [MetaCyc:RXN0-280] +synonym: "alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity" EXACT [EC:1.14.14.5] +synonym: "alkanesulphonate monooxygenase activity" EXACT [] +synonym: "FMNH(2)-dependent aliphatic sulfonate monooxygenase activity" EXACT [EC:1.14.14.5] +synonym: "FMNH(2)-dependent alkanesulfonate monooxygenase activity" EXACT [] +synonym: "FMNH2-dependent aliphatic sulfonate monooxygenase activity" EXACT [EC:1.14.14.5] +synonym: "SsuD" RELATED [EC:1.14.14.5] +synonym: "sulfate starvation-induced protein 6 activity" RELATED [EC:1.14.14.5] +xref: EC:1.14.14.5 +xref: MetaCyc:RXN0-280 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0008727 +name: GDP-mannose mannosyl hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+." [MetaCyc:GDPMANMANHYDRO-RXN] +xref: MetaCyc:GDPMANMANHYDRO-RXN +is_a: GO:0015923 ! mannosidase activity + +[Term] +id: GO:0008728 +name: GTP diphosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate." [EC:2.7.6.5] +synonym: "(p)ppGpp synthetase I" RELATED [EC:2.7.6.5] +synonym: "(p)ppGpp synthetase II" RELATED [EC:2.7.6.5] +synonym: "ATP-GTP 3'-diphosphotransferase activity" EXACT [EC:2.7.6.5] +synonym: "ATP:GTP 3'-diphosphotransferase activity" EXACT [EC:2.7.6.5] +synonym: "GPSI" RELATED [EC:2.7.6.5] +synonym: "GPSII" RELATED [EC:2.7.6.5] +synonym: "GTP pyrophosphokinase activity" EXACT [] +synonym: "guanosine 3',5'-polyphosphate synthase activity" EXACT [EC:2.7.6.5] +synonym: "guanosine 5',3'-polyphosphate synthetase activity" EXACT [EC:2.7.6.5] +synonym: "guanosine pentaphosphate synthetase activity" EXACT [EC:2.7.6.5] +synonym: "ppGpp synthetase I activity" EXACT [EC:2.7.6.5] +synonym: "stringent factor activity" RELATED [EC:2.7.6.5] +xref: EC:2.7.6.5 +xref: MetaCyc:GTPPYPHOSKIN-RXN +xref: RHEA:22088 +is_a: GO:0016778 ! diphosphotransferase activity + +[Term] +id: GO:0008730 +name: L(+)-tartrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate." [EC:4.2.1.32, RHEA:15413] +synonym: "(R,R)-tartrate hydro-lyase (oxaloacetate-forming)" EXACT [EC:4.2.1.32] +synonym: "(R,R)-tartrate hydro-lyase activity" EXACT [EC:4.2.1.32] +synonym: "L-(+)-tartaric acid dehydratase activity" EXACT [EC:4.2.1.32] +synonym: "L-tartrate dehydratase activity" EXACT [EC:4.2.1.32] +synonym: "tartaric acid dehydrase activity" EXACT [EC:4.2.1.32] +synonym: "tartrate dehydratase activity" EXACT [EC:4.2.1.32] +xref: EC:4.2.1.32 +xref: KEGG_REACTION:R00339 +xref: MetaCyc:LTARTDEHYDRA-RXN +xref: RHEA:15413 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008732 +name: L-allo-threonine aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde." [MetaCyc:LTAA-RXN, PMID:9228760] +synonym: "L-allo-threonine acetaldehyde-lyase activity" EXACT [] +synonym: "LtaA" RELATED [] +xref: EC:4.1.2 +xref: MetaCyc:LTAA-RXN +is_a: GO:0004793 ! threonine aldolase activity + +[Term] +id: GO:0008733 +name: L-arabinose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinose = L-ribulose." [EC:5.3.1.4, RHEA:14821] +synonym: "L-arabinose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.4] +synonym: "L-arabinose ketol-isomerase activity" EXACT [EC:5.3.1.4] +xref: EC:5.3.1.4 +xref: KEGG_REACTION:R01761 +xref: MetaCyc:ARABISOM-RXN +xref: RHEA:14821 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008734 +name: L-aspartate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide." [EC:1.4.3.16] +synonym: "L-aspartate:oxygen oxidoreductase" EXACT [EC:1.4.3.16] +xref: EC:1.4.3.16 +xref: MetaCyc:L-ASPARTATE-OXID-RXN +xref: MetaCyc:RXN-9772 +xref: RHEA:25876 +is_a: GO:0001716 ! L-amino-acid oxidase activity +is_a: GO:0015922 ! aspartate oxidase activity + +[Term] +id: GO:0008735 +name: carnitine dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O." [EC:4.2.1.89, RHEA:14577] +synonym: "L-carnitine dehydratase activity" EXACT [] +synonym: "L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]" RELATED [EC:4.2.1.89] +synonym: "L-carnitine hydro-lyase activity" EXACT [EC:4.2.1.89] +xref: EC:4.2.1.89 +xref: KEGG_REACTION:R01925 +xref: MetaCyc:CARNDEHYDRA-RXN +xref: RHEA:14577 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008736 +name: L-fucose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-fucose = L-fuculose." [EC:5.3.1.25] +synonym: "L-fucose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.25] +synonym: "L-fucose ketol-isomerase activity" EXACT [EC:5.3.1.25] +xref: EC:5.3.1.25 +xref: MetaCyc:FUCISOM-RXN +xref: RHEA:17233 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008737 +name: L-fuculokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.51, RHEA:12376] +synonym: "ATP:L-fuculose 1-phosphotransferase activity" EXACT [EC:2.7.1.51] +synonym: "L-fuculokinase (phosphorylating)" EXACT [EC:2.7.1.51] +synonym: "L-fuculose kinase activity" EXACT [EC:2.7.1.51] +xref: EC:2.7.1.51 +xref: KEGG_REACTION:R03241 +xref: MetaCyc:FUCULOKIN-RXN +xref: RHEA:12376 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008738 +name: L-fuculose-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate." [EC:4.1.2.17, RHEA:12933] +synonym: "fuculose aldolase activity" EXACT [EC:4.1.2.17] +synonym: "L-fuculose 1-phosphate aldolase activity" EXACT [EC:4.1.2.17] +synonym: "L-fuculose-1-phosphate lactaldehyde-lyase activity" EXACT [EC:4.1.2.17] +synonym: "L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.17] +xref: EC:4.1.2.17 +xref: KEGG_REACTION:R02262 +xref: MetaCyc:FUCPALDOL-RXN +xref: RHEA:12933 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008740 +name: L-rhamnose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-rhamnose = L-rhamnulose." [EC:5.3.1.14, RHEA:23160] +synonym: "L-rhamnose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.14] +synonym: "L-rhamnose ketol-isomerase activity" EXACT [EC:5.3.1.14] +synonym: "rhamnose isomerase activity" EXACT [EC:5.3.1.14] +xref: EC:5.3.1.14 +xref: KEGG_REACTION:R02437 +xref: MetaCyc:RHAMNISOM-RXN +xref: RHEA:23160 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008741 +name: ribulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate." [EC:2.7.1.16] +synonym: "ATP:L(or D)-ribulose 5-phosphotransferase activity" EXACT [EC:2.7.1.16] +synonym: "L-ribulokinase activity" EXACT [] +synonym: "ribulokinase (phosphorylating)" EXACT [EC:2.7.1.16] +xref: EC:2.7.1.16 +xref: MetaCyc:RIBULOKIN-RXN +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008742 +name: L-ribulose-phosphate 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate." [EC:5.1.3.4, RHEA:22368] +synonym: "AraD" RELATED [EC:5.1.3.4] +synonym: "L-ribulose 5-phosphate 4-epimerase activity" EXACT [EC:5.1.3.4] +synonym: "L-ribulose-5-phosphate 4-epimerase" BROAD [EC:5.1.3.4] +synonym: "L-Ru5P" RELATED [EC:5.1.3.4] +synonym: "L-ru5P activity" EXACT [EC:5.1.3.4] +synonym: "phosphoribulose isomerase activity" EXACT [EC:5.1.3.4] +synonym: "ribulose phosphate 4-epimerase activity" EXACT [EC:5.1.3.4] +xref: EC:5.1.3.4 +xref: KEGG_REACTION:R05850 +xref: MetaCyc:RIBULPEPIM-RXN +xref: RHEA:22368 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0008743 +name: L-threonine 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + CO(2) + NADH." [EC:1.1.1.103, RHEA:13161] +synonym: "L-threonine dehydrogenase activity" EXACT [EC:1.1.1.103] +synonym: "L-threonine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.103] +synonym: "threonine 3-dehydrogenase activity" BROAD [] +synonym: "threonine dehydrogenase activity" EXACT [EC:1.1.1.103] +xref: EC:1.1.1.103 +xref: KEGG_REACTION:R01465 +xref: MetaCyc:THREODEHYD-RXN +xref: Reactome:R-HSA-6798667 "TDH tetramer oxidises L-Thr to 2A-3OB" +xref: RHEA:13161 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008744 +name: L-xylulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate." [EC:2.7.1.53] +synonym: "ATP:L-xylulose 5-phosphotransferase activity" EXACT [EC:2.7.1.53] +synonym: "L-xylulokinase (phosphorylating)" EXACT [EC:2.7.1.53] +synonym: "L-xylulose kinase activity" EXACT [EC:2.7.1.53] +xref: EC:2.7.1.53 +xref: MetaCyc:LYXK-RXN +xref: RHEA:18869 +is_a: GO:0004856 ! xylulokinase activity + +[Term] +id: GO:0008745 +name: N-acetylmuramoyl-L-alanine amidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides." [EC:3.5.1.28, PMID:22748813] +synonym: "acetylmuramoyl-alanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "acetylmuramyl-alanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "acetylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "N-acetylmuramic acid L-alanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "N-acetylmuramoyl-L-alanine amidase type I" RELATED [EC:3.5.1.28] +synonym: "N-acetylmuramoyl-L-alanine amidase type II" RELATED [EC:3.5.1.28] +synonym: "N-acetylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "N-acetylmuramylalanine amidase activity" EXACT [EC:3.5.1.28] +synonym: "N-acylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] +xref: EC:3.5.1.28 +xref: MetaCyc:3.5.1.28-RXN +xref: Reactome:R-HSA-6799977 "PGLYRP2 hydrolyzes bacterial peptidoglycan" +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0061783 ! peptidoglycan muralytic activity + +[Term] +id: GO:0008746 +name: NAD(P)+ transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+." [EC:1.6.1.1, EC:1.6.1.2] +synonym: "energy-linked transhydrogenase" EXACT [EC:1.6.1.1, EC:1.6.1.2] +synonym: "H+-thase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NAD transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NADH transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NADH-NADP-transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NADPH-NAD oxidoreductase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NADPH-NAD transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "NADPH:NAD+ transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "nicotinamide adenine dinucleotide (phosphate) transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +synonym: "pyridine nucleotide transferase" BROAD [EC:1.6.1.1, EC:1.6.1.2] +xref: EC:1.6.1.1 +xref: KEGG_REACTION:R00112 +xref: Reactome:R-HSA-450971 "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]" +xref: RHEA:11692 +is_a: GO:0016652 ! oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor + +[Term] +id: GO:0008747 +name: N-acetylneuraminate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate." [EC:4.1.3.3, RHEA:23296] +synonym: "acetylneuraminate lyase activity" EXACT [EC:4.1.3.3] +synonym: "acetylneuraminate pyruvate-lyase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminate aldolase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminate pyruvate-lyase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminic acid aldolase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminic acid lyase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminic aldolase activity" EXACT [EC:4.1.3.3] +synonym: "N-acetylneuraminic lyase activity" EXACT [EC:4.1.3.3] +synonym: "NALase activity" EXACT [EC:4.1.3.3] +synonym: "NANA lyase activity" EXACT [EC:4.1.3.3] +synonym: "neuraminate aldolase activity" EXACT [EC:4.1.3.3] +synonym: "neuraminic acid aldolase activity" EXACT [EC:4.1.3.3] +synonym: "neuraminic aldolase activity" EXACT [EC:4.1.3.3] +synonym: "NPL" RELATED [EC:4.1.3.3] +synonym: "sialate lyase activity" EXACT [EC:4.1.3.3] +synonym: "sialic acid aldolase activity" EXACT [EC:4.1.3.3] +synonym: "sialic aldolase activity" EXACT [EC:4.1.3.3] +xref: EC:4.1.3.3 +xref: KEGG_REACTION:R01811 +xref: MetaCyc:ACNEULY-RXN +xref: Reactome:R-HSA-4085217 "NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate" +xref: RHEA:23296 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008748 +name: N-ethylmaleimide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+." [MetaCyc:RXN0-5101] +xref: MetaCyc:RXN0-5101 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008750 +name: NAD(P)+ transhydrogenase (AB-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+." [EC:1.6.1.2, http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf] +synonym: "NAD(P) transhydrogenase (AB-specific) activity" EXACT [EC:1.6.1.2] +synonym: "NADPH:NAD+ oxidoreductase (AB-specific)" EXACT [EC:1.6.1.2] +synonym: "pyridine nucleotide transhydrogenase activity" BROAD [EC:1.6.1.2] +synonym: "transhydrogenase activity" BROAD [EC:1.6.1.2] +xref: EC:1.6.1.2 +xref: MetaCyc:1.6.1.2-RXN +is_a: GO:0008746 ! NAD(P)+ transhydrogenase activity + +[Term] +id: GO:0008751 +name: obsolete NAD(P)H dehydrogenase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it is a redundant grouping term with only one child. +synonym: "NAD(P)H dehydrogenase" EXACT [] +is_obsolete: true +consider: GO:0016651 + +[Term] +id: GO:0008752 +name: FMN reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+." [EC:1.5.1.29] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "flavin mononucleotide reductase activity" EXACT [EC:1.5.1.29] +synonym: "flavine mononucleotide reductase activity" EXACT [EC:1.5.1.29] +synonym: "FMNH2:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H dehydrogenase (FMN) activity" EXACT [] +synonym: "NAD(P)H(2) dehydrogenase (FMN) activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H(2):FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H-dependent FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H-FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H2 dehydrogenase (FMN)" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H2:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H:flavin oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NAD(P)H:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity" EXACT [EC:1.5.1.29] +synonym: "riboflavin mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "riboflavine mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "SsuE" RELATED [EC:1.5.1.29] +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008753 +name: NADPH dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol." [EC:1.6.5.10] +synonym: "NADPH oxidase" BROAD [EC:1.6.5.10] +synonym: "NADPH:(quinone-acceptor) oxidoreductase" EXACT [EC:1.6.5.10] +synonym: "reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase" EXACT [EC:1.6.5.10] +xref: EC:1.6.5.10 +xref: KEGG_REACTION:R07359 +xref: MetaCyc:NADPH-DEHYDROGENASE-QUINONE-RXN +xref: RHEA:13149 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0008754 +name: O antigen ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: Lipid A-core + colanic acid = MLPS." [MetaCyc:RXN0-5294] +xref: MetaCyc:RXN0-5294 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0008755 +name: O antigen polymerase activity +namespace: molecular_function +def: "Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide." [GOC:jl, PMID:12045108] +synonym: "O-antigen polymerase activity" EXACT [] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008756 +name: o-succinylbenzoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate." [EC:6.2.1.26] +synonym: "2-succinylbenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.26] +synonym: "o-succinylbenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.26] +synonym: "o-succinylbenzoyl-CoA synthetase activity" EXACT [EC:6.2.1.26] +synonym: "o-succinylbenzoyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.26] +synonym: "OSB-CoA synthetase activity" EXACT [EC:6.2.1.26] +xref: EC:6.2.1.26 +xref: KEGG_REACTION:R04030 +xref: MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN +xref: RHEA:17009 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0008757 +name: S-adenosylmethionine-dependent methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate." [GOC:mah] +synonym: "S-adenosyl methionine-dependent methyltransferase activity" EXACT [] +synonym: "SAM-dependent methyltransferase activity" EXACT [] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0008758 +name: UDP-2,3-diacylglucosamine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP." [MetaCyc:LIPIDXSYNTHESIS-RXN, PMID:12000770] +xref: MetaCyc:LIPIDXSYNTHESIS-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0008759 +name: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity +namespace: molecular_function +def: "Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine." [PMID:10026271] +xref: EC:3.5.1.108 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0008760 +name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine." [EC:2.5.1.7, RHEA:18681] +synonym: "enoylpyruvate transferase activity" EXACT [EC:2.5.1.7] +synonym: "MurA transferase activity" NARROW [EC:2.5.1.7] +synonym: "phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity" EXACT [EC:2.5.1.7] +synonym: "pyruvate-UDP-acetylglucosamine transferase activity" EXACT [EC:2.5.1.7] +synonym: "pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity" EXACT [EC:2.5.1.7] +synonym: "pyruvate-uridine diphospho-N-acetylglucosamine transferase activity" EXACT [EC:2.5.1.7] +synonym: "pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity" EXACT [EC:2.5.1.7] +synonym: "UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity" EXACT [EC:2.5.1.7] +synonym: "UDP-N-acetylglucosamine enoylpyruvyltransferase activity" EXACT [EC:2.5.1.7] +xref: EC:2.5.1.7 +xref: KEGG_REACTION:R00660 +xref: MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN +xref: RHEA:18681 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0008761 +name: UDP-N-acetylglucosamine 2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine." [EC:5.1.3.14] +synonym: "UDP-GlcNAc-2-epimerase activity" EXACT [EC:5.1.3.14] +synonym: "UDP-N-acetyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.14] +synonym: "UDP-N-acetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] +synonym: "uridine diphosphate-N-acetylglucosamine-2'-epimerase activity" EXACT [EC:5.1.3.14] +synonym: "uridine diphospho-N-acetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] +synonym: "uridine diphosphoacetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] +xref: EC:5.1.3.14 +xref: MetaCyc:UDPGLCNACEPIM-RXN +xref: Reactome:R-HSA-4085021 "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP" +xref: Reactome:R-HSA-4088338 "Defective GNE does not hydrolyse UDP-GlcNAc" +xref: RHEA:17213 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0008762 +name: UDP-N-acetylmuramate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+." [EC:1.3.1.98] +synonym: "MurB reductase" RELATED [EC:1.3.1.98] +synonym: "UDP-GlcNAc-enoylpyruvate reductase activity" EXACT [EC:1.3.1.98] +synonym: "UDP-N-acetylenolpyruvoylglucosamine reductase activity" EXACT [EC:1.3.1.98] +synonym: "UDP-N-acetylglucosamine-enoylpyruvate reductase activity" EXACT [EC:1.3.1.98] +synonym: "UDP-N-acetylmuramate:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.98] +synonym: "uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity" EXACT [EC:1.3.1.98] +synonym: "uridine diphosphoacetylpyruvoylglucosamine reductase activity" EXACT [EC:1.3.1.98] +synonym: "uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity" EXACT [EC:1.3.1.98] +xref: EC:1.3.1.98 +xref: MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN +xref: RHEA:12248 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008763 +name: UDP-N-acetylmuramate-L-alanine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine." [EC:6.3.2.8, RHEA:23372] +synonym: "alanine-adding enzyme activity" RELATED [EC:6.3.2.8] +synonym: "L-Ala ligase activity" RELATED [EC:6.3.2.8] +synonym: "L-alanine-adding enzyme activity" RELATED [EC:6.3.2.8] +synonym: "MurC synthetase activity" NARROW [EC:6.3.2.8] +synonym: "UDP-acetylmuramyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "UDP-MurNAc:L-alanine ligase activity" EXACT [EC:6.3.2.8] +synonym: "UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.8] +synonym: "UDP-N-acetylmuramoyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "UDP-N-acetylmuramoylalanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "UDP-N-acetylmuramyl:L-alanine ligase activity" EXACT [EC:6.3.2.8] +synonym: "UDPMurNAc-L-alanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "uridine diphosphate N-acetylmuramate:L-alanine ligase activity" EXACT [EC:6.3.2.8] +synonym: "uridine diphospho-N-acetylmuramoylalanine synthetase activity" EXACT [EC:6.3.2.8] +synonym: "uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity" EXACT [EC:6.3.2.8] +xref: EC:6.3.2.8 +xref: KEGG_REACTION:R03193 +xref: MetaCyc:UDP-NACMUR-ALA-LIG-RXN +xref: RHEA:23372 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0008764 +name: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate." [EC:6.3.2.9, RHEA:16429] +synonym: "D-glutamate ligase activity" RELATED [EC:6.3.2.9] +synonym: "D-glutamate-adding enzyme activity" RELATED [EC:6.3.2.9] +synonym: "MurD synthetase activity" EXACT [EC:6.3.2.9] +synonym: "UDP-Mur-NAC-L-Ala:D-Glu ligase activity" EXACT [EC:6.3.2.9] +synonym: "UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)" EXACT [EC:6.3.2.9] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity" EXACT [EC:6.3.2.9] +synonym: "uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity" EXACT [EC:6.3.2.9] +xref: EC:6.3.2.9 +xref: KEGG_REACTION:R02783 +xref: MetaCyc:UDP-NACMURALA-GLU-LIG-RXN +xref: RHEA:16429 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0008765 +name: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate." [EC:6.3.2.13, RHEA:23676] +synonym: "MurE synthetase activity" RELATED [EC:6.3.2.13] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.13] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity" EXACT [EC:6.3.2.13] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity" EXACT [EC:6.3.2.13] +synonym: "UDP-N-acetylmuramyl-tripeptide synthetase activity" EXACT [EC:6.3.2.13] +xref: EC:6.3.2.13 +xref: KEGG_REACTION:R02788 +xref: MetaCyc:UDP-NACMURALGLDAPLIG-RXN +xref: RHEA:23676 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0008766 +name: UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine." [EC:6.3.2.15] +comment: Note that EC:6.3.2.15 was deleted from EC as the reaction is performed by UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (EC:6.3.2.10). +xref: EC:6.3.2 +xref: MetaCyc:UDP-NACMURALGLDAPAALIG-RXN +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0008767 +name: UDP-galactopyranose mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose." [EC:5.4.99.9] +synonym: "UDP-D-galactopyranose furanomutase activity" EXACT [EC:5.4.99.9] +synonym: "UDPgalactopyranose mutase activity" EXACT [EC:5.4.99.9] +xref: EC:5.4.99.9 +xref: MetaCyc:GALPMUT-RXN +xref: RHEA:24132 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0008768 +name: UDP-sugar diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate." [EC:3.6.1.45] +synonym: "nucleosidediphosphate-sugar diphosphatase activity" EXACT [EC:3.6.1.45] +synonym: "nucleosidediphosphate-sugar pyrophosphatase activity" EXACT [EC:3.6.1.45] +synonym: "UDP-sugar hydrolase activity" EXACT [EC:3.6.1.45] +synonym: "UDP-sugar pyrophosphatase activity" EXACT [EC:3.6.1.45] +synonym: "UDP-sugar sugarphosphohydrolase activity" EXACT [EC:3.6.1.45] +xref: EC:3.6.1.45 +xref: MetaCyc:UDPSUGARHYDRO-RXN +xref: Reactome:R-HSA-6810464 "NUDT14 hydrolyses UDP-Glc to G1P and UMP" +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0008769 +name: obsolete X-His dipeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of Xaa-His dipeptides." [EC:3.4.13.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminoacyl-histidine dipeptidase activity" EXACT [EC:3.4.13.3] +synonym: "aminoacylhistidine dipeptidase activity" EXACT [EC:3.4.13.3] +synonym: "carnosinase activity" RELATED [EC:3.4.13.3] +synonym: "dipeptidase M" RELATED [EC:3.4.13.3] +synonym: "homocarnosinase activity" RELATED [EC:3.4.13.3] +synonym: "X-His dipeptidase activity" EXACT [] +synonym: "Xaa-His dipeptidase activity" EXACT [] +xref: EC:3.4.13.3 +xref: MetaCyc:3.4.13.3-RXN +is_obsolete: true +consider: GO:0008235 +consider: GO:0016805 + +[Term] +id: GO:0008770 +name: [acyl-carrier-protein] phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein." [EC:3.1.4.14] +synonym: "[acyl-carrier protein] phosphodiesterase activity" EXACT [] +synonym: "[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] +synonym: "ACP hydrolyase activity" EXACT [EC:3.1.4.14] +synonym: "ACP phosphodiesterase activity" EXACT [] +synonym: "AcpH" RELATED [EC:3.1.4.14] +synonym: "acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] +synonym: "acyl-carrier-protein phosphodiesterase activity" EXACT [EC:3.1.4.14] +synonym: "holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] +xref: EC:3.1.4.14 +xref: MetaCyc:3.1.4.14-RXN +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008771 +name: [citrate (pro-3S)-lyase] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form)." [EC:6.2.1.22] +synonym: "acetate: SH-acyl-carrier-protein enzyme ligase (AMP)" EXACT [EC:6.2.1.22] +synonym: "acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)" BROAD [EC:6.2.1.22] +synonym: "acetate:HS-citrate lyase ligase activity" EXACT [EC:6.2.1.22] +synonym: "citrate (pro-3S)-lyase ligase activity" EXACT [EC:6.2.1.22] +synonym: "citrate lyase ligase activity" EXACT [EC:6.2.1.22] +synonym: "citrate lyase synthetase activity" EXACT [EC:6.2.1.22] +xref: EC:6.2.1.22 +xref: KEGG_REACTION:R04449 +xref: MetaCyc:CITC-RXN +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0008772 +name: [isocitrate dehydrogenase (NADP+)] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate." [EC:2.7.11.5] +synonym: "ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity" EXACT [EC:2.7.11.5] +synonym: "ICDH kinase/phosphatase activity" BROAD [EC:2.7.11.5] +synonym: "IDH kinase activity" EXACT [EC:2.7.11.5] +synonym: "IDH kinase/phosphatase activity" BROAD [EC:2.7.11.5] +synonym: "IDH-K/P" RELATED [EC:2.7.11.5] +synonym: "IDHK/P" BROAD [EC:2.7.11.5] +synonym: "isocitrate dehydrogenase (NADP) kinase activity" EXACT [EC:2.7.11.5] +synonym: "isocitrate dehydrogenase (NADP+) kinase activity" EXACT [EC:2.7.11.5] +synonym: "isocitrate dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.5] +synonym: "isocitrate dehydrogenase kinase activity" EXACT [EC:2.7.11.5] +synonym: "isocitrate dehydrogenase kinase/phosphatase activity" BROAD [EC:2.7.11.5] +xref: EC:2.7.11.5 +xref: MetaCyc:PHOSICITDEHASE-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0008773 +name: [protein-PII] uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII)." [EC:2.7.7.59] +synonym: "PII uridylyl-transferase activity" EXACT [EC:2.7.7.59] +synonym: "protein-PII uridylyltransferase activity" EXACT [EC:2.7.7.59] +synonym: "uridyl removing enzyme" RELATED [EC:2.7.7.59] +synonym: "uridylyl removing enzyme activity" BROAD [EC:2.7.7.59] +synonym: "UTP:[protein-PII] uridylyltransferase activity" EXACT [] +synonym: "UTP:protein-PII uridylyltransferase activity" EXACT [EC:2.7.7.59] +xref: EC:2.7.7.59 +xref: MetaCyc:URITRANS-RXN +is_a: GO:0070569 ! uridylyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008774 +name: acetaldehyde dehydrogenase (acetylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+." [EC:1.2.1.10] +synonym: "acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.1.10] +synonym: "acylating acetaldehyde dehydrogenase activity" EXACT [EC:1.2.1.10] +synonym: "ADA" RELATED [EC:1.2.1.10] +synonym: "aldehyde dehydrogenase (acylating) activity" EXACT [EC:1.2.1.10] +synonym: "DmpF" RELATED [EC:1.2.1.10] +xref: EC:1.2.1.10 +xref: MetaCyc:ACETALD-DEHYDROG-RXN +xref: RHEA:23288 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008775 +name: acetate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA." [EC:2.8.3.8] +synonym: "acetate coenzyme A-transferase activity" EXACT [EC:2.8.3.8] +synonym: "acetyl-CoA:acetoacetate CoA transferase activity" EXACT [EC:2.8.3.8] +synonym: "acyl-CoA:acetate CoA-transferase activity" EXACT [EC:2.8.3.8] +synonym: "butyryl CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.8] +synonym: "butyryl coenzyme A transferase activity" EXACT [EC:2.8.3.8] +synonym: "succinyl-CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.8] +xref: EC:2.8.3.8 +xref: MetaCyc:ACECOATRANS-RXN +xref: Reactome:R-HSA-2066788 "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase" +xref: RHEA:13381 +xref: UM-BBD_enzymeID:e0012 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0008776 +name: acetate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate." [EC:2.7.2.1] +synonym: "acetate kinase (phosphorylating) activity" EXACT [EC:2.7.2.1] +synonym: "acetic kinase activity" EXACT [EC:2.7.2.1] +synonym: "acetokinase activity" EXACT [EC:2.7.2.1] +synonym: "AckA" RELATED [EC:2.7.2.1] +synonym: "AK activity" EXACT [EC:2.7.2.1] +synonym: "ATP:acetate phosphotransferase activity" EXACT [EC:2.7.2.1] +xref: EC:2.7.2.1 +xref: MetaCyc:ACETATEKIN-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0008777 +name: acetylornithine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine." [EC:3.5.1.16] +synonym: "2-N-acetyl-L-ornithine amidohydrolase activity" EXACT [EC:3.5.1.16] +synonym: "acetylornithinase activity" BROAD [EC:3.5.1.16] +synonym: "N-acetylornithinase activity" BROAD [EC:3.5.1.16] +synonym: "N2-acetyl-L-ornithine amidohydrolase activity" EXACT [EC:3.5.1.16] +xref: EC:3.5.1.16 +xref: MetaCyc:ACETYLORNDEACET-RXN +xref: RHEA:15941 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0008779 +name: acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine." [EC:2.3.1.40] +synonym: "acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity" EXACT [] +synonym: "acyl-ACP-phospholipid O-acyltransferase activity" EXACT [] +synonym: "acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity" EXACT [EC:2.3.1.40] +synonym: "acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity" EXACT [EC:2.3.1.40] +xref: EC:2.3.1.40 +xref: MetaCyc:ACYLGPEACYLTRANS-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0008780 +name: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine." [EC:2.3.1.129] +synonym: "(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity" EXACT [EC:2.3.1.129] +synonym: "acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity" EXACT [] +synonym: "acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity" EXACT [] +synonym: "acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase" BROAD [EC:2.3.1.129] +synonym: "UDP-N-acetylglucosamine acyltransferase activity" EXACT [EC:2.3.1.129] +synonym: "uridine diphosphoacetylglucosamine acyltransferase activity" EXACT [EC:2.3.1.129] +xref: EC:2.3.1.129 +xref: MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0008781 +name: N-acylneuraminate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate." [EC:2.7.7.43] +synonym: "acetylneuraminate cytidylyltransferase activity" EXACT [EC:2.7.7.43] +synonym: "acylneuraminate cytidyltransferase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-N-acetylneuraminate synthase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-N-acetylneuraminate synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-N-acetylneuraminic acid synthase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-NANA synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-Neu5Ac synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-NeuAc synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-NeuNAc synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialate diphosphorylase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialate pyrophosphorylase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialate synthase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialate synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialic acid synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CMP-sialic synthetase activity" EXACT [EC:2.7.7.43] +synonym: "CTP:N-acylneuraminate cytidylyltransferase activity" EXACT [] +synonym: "cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine 5'-monophosphosialic acid synthetase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine monophosphoacetylneuraminic synthetase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine monophosphosialate pyrophosphorylase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine monophosphosialate synthetase activity" EXACT [EC:2.7.7.43] +synonym: "cytidine monophosphosialic acid synthetase activity" EXACT [EC:2.7.7.43] +xref: EC:2.7.7.43 +xref: MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN +xref: Reactome:R-HSA-4084982 "CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac" +xref: RHEA:11344 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0008782 +name: adenosylhomocysteine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine." [EC:3.2.2.9] +synonym: "5'-methyladenosine nucleosidase activity" EXACT [EC:3.2.2.9] +synonym: "AdoHcy/MTA nucleosidase activity" EXACT [EC:3.2.2.9] +synonym: "S-adenosyl-L-homocysteine homocysteinylribohydrolase activity" EXACT [EC:3.2.2.9] +synonym: "S-adenosylhomocysteine hydrolase activity" BROAD [EC:3.2.2.9] +synonym: "S-adenosylhomocysteine nucleosidase activity" EXACT [EC:3.2.2.9] +synonym: "S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity" EXACT [EC:3.2.2.9] +xref: EC:3.2.2.9 +xref: MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0008783 +name: agmatinase activity +namespace: molecular_function +def: "Catalysis of the reaction: agmatine + H(2)O = putrescine + urea." [EC:3.5.3.11, RHEA:13929] +synonym: "agmatine amidinohydrolase" BROAD [EC:3.5.3.11] +synonym: "agmatine ureohydrolase activity" EXACT [EC:3.5.3.11] +synonym: "SpeB" RELATED [EC:3.5.3.11] +xref: EC:3.5.3.11 +xref: KEGG_REACTION:R01157 +xref: MetaCyc:AGMATIN-RXN +xref: Reactome:R-HSA-350604 "Agmatine + H2O <=> putrescine + urea" +xref: RHEA:13929 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0008784 +name: alanine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine = D-alanine." [EC:5.1.1.1, RHEA:20249] +synonym: "L-alanine racemase activity" EXACT [EC:5.1.1.1] +xref: EC:5.1.1.1 +xref: KEGG_REACTION:R00401 +xref: MetaCyc:ALARACECAT-RXN +xref: RHEA:20249 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0008785 +name: alkyl hydroperoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol." [UM-BBD_reactionID:r0684] +xref: Reactome:R-HSA-1222526 "AhpC reduces peroxidated lipids" +xref: UM-BBD_reactionID:r0684 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0008786 +name: allose 6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate." [MetaCyc:RXN0-303] +xref: MetaCyc:RXN0-303 +xref: RHEA:28430 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008787 +name: allose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate." [EC:2.7.1.55] +synonym: "allokinase (phosphorylating)" EXACT [EC:2.7.1.55] +synonym: "allokinase activity" EXACT [EC:2.7.1.55] +synonym: "ATP:D-allose 6-phosphotransferase activity" EXACT [EC:2.7.1.55] +synonym: "D-allokinase activity" EXACT [EC:2.7.1.55] +synonym: "D-allose-6-kinase activity" EXACT [EC:2.7.1.55] +xref: EC:2.7.1.55 +xref: MetaCyc:ALLOSE-KINASE-RXN +xref: RHEA:14805 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008788 +name: alpha,alpha-phosphotrehalase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate." [EC:3.2.1.93] +synonym: "alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity" EXACT [EC:3.2.1.93] +synonym: "phosphotrehalase activity" EXACT [EC:3.2.1.93] +synonym: "trehalose-6-phosphate hydrolase activity" EXACT [EC:3.2.1.93] +xref: EC:3.2.1.93 +xref: MetaCyc:TRE6PHYDRO-RXN +xref: RHEA:23008 +is_a: GO:0015927 ! trehalase activity + +[Term] +id: GO:0008789 +name: altronate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O." [EC:4.2.1.7, RHEA:15957] +synonym: "D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)" EXACT [EC:4.2.1.7] +synonym: "D-altronate hydro-lyase activity" EXACT [EC:4.2.1.7] +xref: EC:4.2.1.7 +xref: KEGG_REACTION:R01540 +xref: MetaCyc:ALTRODEHYDRAT-RXN +xref: RHEA:15957 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008790 +name: arabinose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose = D-ribulose." [EC:5.3.1.3] +synonym: "D-arabinose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.3] +synonym: "D-arabinose isomerase activity" NARROW [EC:5.3.1.3] +synonym: "D-arabinose ketol-isomerase activity" EXACT [EC:5.3.1.3] +synonym: "D-arabinose(L-fucose) isomerase activity" EXACT [EC:5.3.1.3] +xref: EC:5.3.1.3 +xref: MetaCyc:DARABISOM-RXN +xref: RHEA:13849 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008791 +name: arginine N-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine." [EC:2.3.1.109] +synonym: "AOST activity" EXACT [EC:2.3.1.109] +synonym: "arginine and ornithine N(2)-succinyltransferase activity" EXACT [EC:2.3.1.109] +synonym: "arginine and ornithine N2-succinyltransferase activity" EXACT [EC:2.3.1.109] +synonym: "arginine succinyltransferase activity" EXACT [EC:2.3.1.109] +synonym: "AST activity" EXACT [EC:2.3.1.109] +synonym: "AstA" RELATED [EC:2.3.1.109] +synonym: "succinyl-CoA:L-arginine 2-N-succinyltransferase activity" EXACT [EC:2.3.1.109] +synonym: "succinyl-CoA:L-arginine N2-succinyltransferase activity" EXACT [EC:2.3.1.109] +xref: EC:2.3.1.109 +xref: MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN +xref: RHEA:15185 +is_a: GO:0016749 ! N-succinyltransferase activity + +[Term] +id: GO:0008792 +name: arginine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2)." [EC:4.1.1.19, RHEA:17641] +synonym: "L-arginine carboxy-lyase (agmatine-forming)" EXACT [EC:4.1.1.19] +synonym: "L-arginine carboxy-lyase activity" EXACT [EC:4.1.1.19] +synonym: "SpeA" RELATED [EC:4.1.1.19] +xref: EC:4.1.1.19 +xref: KEGG_REACTION:R00566 +xref: MetaCyc:ARGDECARBOX-RXN +xref: Reactome:R-HSA-350598 "Arginine<=>Agmatine+CO2" +xref: RHEA:17641 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008793 +name: aromatic-amino-acid:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate." [EC:2.6.1.57] +synonym: "ArAT" RELATED [EC:2.6.1.57] +synonym: "aromatic amino acid aminotransferase activity" EXACT [EC:2.6.1.57] +synonym: "aromatic amino acid transferase activity" EXACT [] +synonym: "aromatic aminotransferase activity" EXACT [] +synonym: "aromatic-amino-acid transaminase activity" EXACT [EC:2.6.1.57] +xref: EC:2.6.1.57 +xref: MetaCyc:2.6.1.57-RXN +xref: UM-BBD_reactionID:r0297 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0008794 +name: arsenate reductase (glutaredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione." [EC:1.20.4.1, GOC:kd, PMID:10593884] +synonym: "glutharedoxin:arsenate oxidoreductase activity" EXACT [EC:1.20.4.1] +xref: EC:1.20.4.1 +xref: MetaCyc:RXN-982 +xref: UM-BBD_reactionID:r0635 +is_a: GO:0030611 ! arsenate reductase activity +is_a: GO:0030614 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor + +[Term] +id: GO:0008795 +name: NAD+ synthase activity +namespace: molecular_function +alt_id: GO:0008749 +alt_id: GO:0016965 +def: "Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+." [EC:6.3.1.5] +synonym: "deamido-NAD+:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.5] +synonym: "diphosphopyridine nucleotide synthetase activity" EXACT [EC:6.3.1.5] +synonym: "NAD synthase (AMP-forming)" EXACT [] +synonym: "NAD synthase activity" EXACT [] +synonym: "NAD synthetase activity" EXACT [EC:6.3.1.5] +synonym: "NAD(+) synthetase activity" EXACT [EC:6.3.1.5] +synonym: "NAD+ synthetase activity" EXACT [EC:6.3.1.5] +synonym: "nicotinamide adenine dinucleotide synthetase activity" EXACT [EC:6.3.1.5] +xref: EC:6.3.1.5 +xref: MetaCyc:NAD-SYNTH-NH3-RXN +xref: RHEA:21188 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0008796 +name: bis(5'-nucleosyl)-tetraphosphatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides." [GOC:ai] +xref: EC:3.6.1 +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0008797 +name: aspartate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate = fumarate + NH3." [EC:4.3.1.1] +synonym: "aspartase activity" EXACT [EC:4.3.1.1] +synonym: "fumaric aminase activity" EXACT [EC:4.3.1.1] +synonym: "L-aspartase activity" EXACT [EC:4.3.1.1] +synonym: "L-aspartate ammonia-lyase (fumarate-forming)" EXACT [EC:4.3.1.1] +synonym: "L-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.1] +xref: EC:4.3.1.1 +xref: MetaCyc:ASPARTASE-RXN +xref: RHEA:16601 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0008798 +name: beta-aspartyl-peptidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide." [EC:3.4.19.5] +synonym: "beta-aspartyl dipeptidase activity" EXACT [EC:3.4.19.5] +synonym: "beta-aspartyl peptidase activity" EXACT [EC:3.4.19.5] +xref: EC:3.4.19.5 +xref: MetaCyc:3.4.19.5-RXN +xref: Reactome:R-HSA-5692495 "BACE1 cleaves APP(18-770) to APP(18-671) and APP(672-770)" +xref: Reactome:R-HSA-5696365 "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe" +is_a: GO:0008242 ! omega peptidase activity + +[Term] +id: GO:0008800 +name: beta-lactamase activity +namespace: molecular_function +def: "Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid." [EC:3.5.2.6] +synonym: "ampicillinase activity" EXACT [EC:3.5.2.6] +synonym: "beta-lactam hydrolase activity" EXACT [EC:3.5.2.6] +synonym: "beta-lactamase A, B, C" RELATED [EC:3.5.2.6] +synonym: "beta-lactamase AME I" RELATED [EC:3.5.2.6] +synonym: "beta-lactamase I-III" RELATED [EC:3.5.2.6] +synonym: "cephalosporin-beta-lactamase activity" EXACT [EC:3.5.2.6] +synonym: "exopenicillinase activity" EXACT [EC:3.5.2.6] +synonym: "neutrapen" RELATED [EC:3.5.2.6] +synonym: "penicillin amido-beta-lactamhydrolase activity" EXACT [EC:3.5.2.6] +synonym: "penicillin beta-lactamase activity" EXACT [EC:3.5.2.6] +synonym: "penicillinase I, II" RELATED [EC:3.5.2.6] +xref: EC:3.5.2.6 +xref: MetaCyc:BETA-LACTAMASE-RXN +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0008801 +name: beta-phosphoglucomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate." [EC:5.4.2.6, RHEA:20113] +synonym: "beta-D-glucose 1,6-phosphomutase activity" EXACT [EC:5.4.2.6] +xref: EC:5.4.2.6 +xref: KEGG_REACTION:R02728 +xref: MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN +xref: RHEA:20113 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0008802 +name: betaine-aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+." [EC:1.2.1.8] +synonym: "BADH activity" EXACT [EC:1.2.1.8] +synonym: "betaine aldehyde dehydrogenase activity" EXACT [EC:1.2.1.8] +synonym: "betaine aldehyde oxidase activity" EXACT [EC:1.2.1.8] +synonym: "betaine-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.8] +synonym: "BetB" RELATED [EC:1.2.1.8] +xref: EC:1.2.1.8 +xref: MetaCyc:BADH-RXN +xref: Reactome:R-HSA-6797955 "ALDH7A1 oxidises BETALD to BET" +xref: RHEA:15305 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0008803 +name: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity +namespace: molecular_function +def: "Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+)." [EC:3.6.1.41, RHEA:24252] +synonym: "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity" EXACT [EC:3.6.1.41] +synonym: "adenosine tetraphosphate phosphodiesterase activity" EXACT [EC:3.6.1.41] +synonym: "Ap(4)A hydrolase activity" BROAD [EC:3.6.1.41] +synonym: "Ap4A hydrolase activity" BROAD [EC:3.6.1.41] +synonym: "bis(5'-adenosyl) tetraphosphatase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphatase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosine polyphosphate hydrolase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosine tetraphosphatase (symmetrical)" NARROW [] +synonym: "diadenosine tetraphosphate hydrolase activity" EXACT [EC:3.6.1.41] +synonym: "diadenosinetetraphosphatase (symmetrical) activity" EXACT [EC:3.6.1.41] +synonym: "dinucleosidetetraphosphatase (symmetrical) activity" EXACT [EC:3.6.1.41] +synonym: "dinucleosidetetraphosphate (symmetrical)" RELATED [EC:3.6.1.41] +synonym: "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity" EXACT [EC:3.6.1.41] +synonym: "symmetrical diadenosine tetraphosphate hydrolase activity" EXACT [EC:3.6.1.41] +xref: EC:3.6.1.41 +xref: KEGG_REACTION:R00125 +xref: MetaCyc:3.6.1.41-RXN +xref: RHEA:24252 +is_a: GO:0008796 ! bis(5'-nucleosyl)-tetraphosphatase activity + +[Term] +id: GO:0008804 +name: carbamate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate." [EC:2.7.2.2] +synonym: "ATP:carbamate phosphotransferase activity" EXACT [EC:2.7.2.2] +synonym: "carbamoyl phosphokinase activity" EXACT [EC:2.7.2.2] +synonym: "carbamyl phosphokinase activity" EXACT [EC:2.7.2.2] +synonym: "CKase activity" EXACT [EC:2.7.2.2] +xref: EC:2.7.2.2 +xref: MetaCyc:CARBAMATE-KINASE-RXN +xref: RHEA:10152 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0008805 +name: carbon-monoxide oxygenase activity +namespace: molecular_function +alt_id: GO:0018999 +alt_id: GO:0047767 +def: "Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561." [EC:1.2.2.4] +synonym: "carbon monoxide oxidase activity" EXACT [EC:1.2.2.4] +synonym: "carbon monoxide oxygenase (cytochrome b-561) activity" NARROW [EC:1.2.2.4] +synonym: "carbon monoxide oxygenase activity" EXACT [] +synonym: "carbon monoxide,water:cytochrome b-561 oxidoreductase activity" EXACT [EC:1.2.2.4] +synonym: "carbon monoxide:methylene blue oxidoreductase activity" NARROW [EC:1.2.2.4] +synonym: "carbon-monoxide dehydrogenase (cytochrome b-561)" EXACT [EC:1.2.2.4] +synonym: "cytochrome b561" NARROW [] +xref: EC:1.2.2.4 +xref: MetaCyc:1.2.2.4-RXN +xref: UM-BBD_reactionID:r0650 +xref: Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561) +is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor + +[Term] +id: GO:0008806 +name: carboxymethylenebutenolidase activity +namespace: molecular_function +alt_id: GO:0018735 +def: "Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate." [EC:3.1.1.45] +synonym: "4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity" EXACT [EC:3.1.1.45] +synonym: "carboxymethylene butenolide hydrolase activity" EXACT [EC:3.1.1.45] +synonym: "dienelactone hydrolase activity" EXACT [EC:3.1.1.45] +synonym: "maleylacetate enol-lactonase activity" EXACT [EC:3.1.1.45] +xref: EC:3.1.1.45 +xref: MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN +xref: RHEA:12372 +xref: UM-BBD_enzymeID:e0066 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0008807 +name: carboxyvinyl-carboxyphosphonate phosphorylmutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2." [EC:2.7.8.23] +synonym: "1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)" EXACT [EC:2.7.8.23] +synonym: "carboxyphosphonoenolpyruvate phosphonomutase activity" EXACT [EC:2.7.8.23] +synonym: "CPEP phosphonomutase activity" EXACT [EC:2.7.8.23] +xref: EC:2.7.8.23 +xref: MetaCyc:2.7.8.23-RXN +xref: RHEA:14045 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0008808 +name: cardiolipin synthase activity +namespace: molecular_function +alt_id: GO:0043788 +def: "Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol." [GOC:jl] +synonym: "cardiolipin synthase 2 activity" RELATED [] +synonym: "cardiolipin synthetase 2 activity" RELATED [] +synonym: "cardiolipin synthetase activity" BROAD [] +synonym: "diphosphatidylglycerol synthase activity" EXACT [] +xref: EC:2.7.8 +xref: MetaCyc:CARDIOLIPSYN-RXN +xref: RHEA:31451 +is_a: GO:0030572 ! phosphatidyltransferase activity + +[Term] +id: GO:0008809 +name: carnitine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-carnitine = L-carnitine." [MetaCyc:CARNRACE-RXN] +xref: MetaCyc:CARNRACE-RXN +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0008810 +name: cellulase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans." [EC:3.2.1.4] +synonym: "1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.4] +synonym: "9.5 cellulase activity" EXACT [EC:3.2.1.4] +synonym: "alkali cellulase activity" NARROW [EC:3.2.1.4] +synonym: "avicelase activity" RELATED [EC:3.2.1.4] +synonym: "beta-1,4-endoglucan hydrolase activity" BROAD [EC:3.2.1.4] +synonym: "beta-1,4-glucanase activity" BROAD [EC:3.2.1.4] +synonym: "carboxymethyl cellulase activity" NARROW [EC:3.2.1.4] +synonym: "celluase A" RELATED [EC:3.2.1.4] +synonym: "celludextrinase activity" EXACT [EC:3.2.1.4] +synonym: "cellulase A 3" RELATED [EC:3.2.1.4] +synonym: "cellulosin AP" RELATED [EC:3.2.1.4] +synonym: "endo-1,4-beta-D-glucanase activity" BROAD [EC:3.2.1.4] +synonym: "endo-1,4-beta-D-glucanohydrolase activity" BROAD [EC:3.2.1.4] +synonym: "endo-1,4-beta-glucanase activity" BROAD [EC:3.2.1.4] +synonym: "endoglucanase activity" BROAD [EC:3.2.1.4] +synonym: "endoglucanase D" RELATED [EC:3.2.1.4] +synonym: "pancellase SS" RELATED [EC:3.2.1.4] +xref: EC:3.2.1.4 +xref: MetaCyc:RXN-2043 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0008811 +name: chloramphenicol O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA." [EC:2.3.1.28, RHEA:18421] +synonym: "acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity" EXACT [EC:2.3.1.28] +synonym: "CAT I" RELATED [EC:2.3.1.28] +synonym: "CAT II" RELATED [EC:2.3.1.28] +synonym: "CAT III" RELATED [EC:2.3.1.28] +synonym: "chloramphenicol acetylase activity" EXACT [EC:2.3.1.28] +synonym: "chloramphenicol acetyltransferase activity" EXACT [EC:2.3.1.28] +synonym: "chloramphenicol transacetylase activity" EXACT [EC:2.3.1.28] +xref: EC:2.3.1.28 +xref: KEGG_REACTION:R03065 +xref: MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN +xref: RHEA:18421 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0008812 +name: choline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde." [EC:1.1.99.1, RHEA:17433] +synonym: "choline oxidase activity" BROAD [EC:1.1.99.1] +synonym: "choline-cytochrome c reductase activity" RELATED [EC:1.1.99.1] +synonym: "choline:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.1] +synonym: "choline:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.1] +synonym: "choline:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.1] +xref: EC:1.1.99.1 +xref: KEGG_REACTION:R01025 +xref: MetaCyc:CHD-RXN +xref: Reactome:R-HSA-6797961 "CHDH oxidises Cho to BETALD" +xref: RHEA:17433 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0008813 +name: chorismate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate." [EC:4.1.3.40, RHEA:16505] +synonym: "4-hydroxybenzoate synthetase activity" EXACT [] +synonym: "chorismate pyruvate lyase activity" EXACT [] +synonym: "chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity" EXACT [EC:4.1.3.40] +synonym: "CL" RELATED [EC:4.1.3.40] +synonym: "CPL" RELATED [EC:4.1.3.40] +synonym: "UbiC" RELATED [EC:4.1.3.40] +xref: EC:4.1.3.40 +xref: KEGG_REACTION:R01302 +xref: MetaCyc:CHORPYRLY-RXN +xref: RHEA:16505 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008814 +name: citrate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA." [EC:2.8.3.10] +synonym: "acetyl-CoA:citrate CoA-transferase activity" EXACT [EC:2.8.3.10] +xref: EC:2.8.3.10 +xref: MetaCyc:CITTRANS-RXN +xref: RHEA:19405 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0008815 +name: citrate (pro-3S)-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: citrate = acetate + oxaloacetate." [EC:4.1.3.6, RHEA:10760] +synonym: "citrase activity" EXACT [EC:4.1.3.6] +synonym: "citratase activity" EXACT [EC:4.1.3.6] +synonym: "citrate aldolase activity" EXACT [EC:4.1.3.6] +synonym: "citrate lyase activity" EXACT [] +synonym: "citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]" RELATED [EC:4.1.3.6] +synonym: "citrate oxaloacetate-lyase activity" EXACT [EC:4.1.3.6] +synonym: "citric aldolase activity" EXACT [EC:4.1.3.6] +synonym: "citridesmolase activity" EXACT [EC:4.1.3.6] +synonym: "citritase activity" EXACT [EC:4.1.3.6] +xref: EC:4.1.3.6 +xref: KEGG_REACTION:R00362 +xref: MetaCyc:CITLY-RXN +xref: RHEA:10760 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008816 +name: citryl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate." [EC:4.1.3.34] +synonym: "(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.34] +synonym: "(3S)-citryl-CoA oxaloacetate-lyase activity" EXACT [EC:4.1.3.34] +xref: EC:4.1.3.34 +xref: MetaCyc:CITRYLY-RXN +xref: RHEA:20812 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008817 +name: cob(I)yrinic acid a,c-diamide adenosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin." [EC:2.5.1.17] +synonym: "aquacob(I)alamin adenosyltransferase activity" EXACT [EC:2.5.1.17] +synonym: "aquocob(I)alamin vitamin B12s adenosyltransferase activity" RELATED [EC:2.5.1.17] +synonym: "ATP:cob(I)alamin Co-beta-adenosyltransferase activity" EXACT [EC:2.5.1.17] +synonym: "ATP:cob(I)alamin cobeta-adenosyltransferase activity" EXACT [EC:2.5.1.17] +synonym: "ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity" EXACT [EC:2.5.1.17] +synonym: "ATP:corrinoid adenosyltransferase activity" EXACT [EC:2.5.1.17] +synonym: "cob(I)alamin adenosyltransferase activity" EXACT [] +synonym: "CobA" RELATED [EC:2.5.1.17] +synonym: "vitamin B12s adenosyltransferase activity" EXACT [EC:2.5.1.17] +xref: EC:2.5.1.17 +xref: MetaCyc:COBALADENOSYLTRANS-RXN +xref: Reactome:R-HSA-3159253 "MMAB transfers adenosyl group from ATP to cob(I)alamin" +xref: Reactome:R-HSA-3322125 "Defective MMAB does not transfer adenosyl group from ATP to B12s" +xref: RHEA:14725 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0008818 +name: cobalamin 5'-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP." [MetaCyc:COBALAMIN5PSYN-RXN] +xref: MetaCyc:COBALAMIN5PSYN-RXN +xref: RHEA:23560 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0008819 +name: cobinamide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate." [http://www.mblab.gla.ac.uk/, PMID:1655696] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008820 +name: cobinamide phosphate guanylyltransferase activity +namespace: molecular_function +alt_id: GO:0043753 +def: "Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate." [EC:2.7.7.62, RHEA:22712] +synonym: "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase" BROAD [] +synonym: "adenosylcobinamide-phosphate guanylyltransferase activity" EXACT [] +synonym: "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase" BROAD [] +synonym: "CobU" RELATED [] +synonym: "GTP:adenosylcobinamide-phosphate guanylyltransferase activity" EXACT [] +synonym: "GTP:cobinamide phosphate guanylyltransferase activity" EXACT [] +xref: EC:2.7.7.62 +xref: KEGG_REACTION:R05222 +xref: MetaCyc:COBINPGUANYLYLTRANS-RXN +xref: RHEA:22712 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0008821 +name: crossover junction endodeoxyribonuclease activity +namespace: molecular_function +alt_id: GO:0008844 +def: "Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)." [EC:3.1.22.4] +synonym: "crossover junction endoribonuclease activity" EXACT [] +synonym: "cruciform-cutting endonuclease activity" EXACT [EC:3.1.22.-] +synonym: "endo X3" RELATED [EC:3.1.22.4] +synonym: "Endo X3 activity" NARROW [EC:3.1.22.-] +synonym: "endodeoxyribonuclease RUS activity" EXACT [] +synonym: "endonuclease RuvC activity" NARROW [EC:3.1.22.-] +synonym: "endonuclease VII activity" NARROW [EC:3.1.22.-] +synonym: "endonuclease X3 activity" NARROW [EC:3.1.22.-] +synonym: "Hje endonuclease activity" EXACT [EC:3.1.22.-] +synonym: "Holliday junction endonuclease CCE1 activity" NARROW [EC:3.1.22.-] +synonym: "Holliday junction nuclease activity" EXACT [EC:3.1.22.-] +synonym: "Holliday junction resolvase activity" NARROW [EC:3.1.22.-] +synonym: "Holliday junction-cleaving endonuclease activity" EXACT [EC:3.1.22.-] +synonym: "Holliday junction-resolving endoribonuclease activity" NARROW [EC:3.1.22.-] +synonym: "resolving enzyme CCE1 activity" NARROW [EC:3.1.22.-] +synonym: "RusA endonuclease activity" NARROW [EC:3.1.22.-] +synonym: "RusA holliday junction resolvase" NARROW [EC:3.1.22.4] +synonym: "RusA Holliday junction resolvase activity" NARROW [EC:3.1.22.-] +synonym: "RuvC endonuclease activity" NARROW [EC:3.1.22.-] +synonym: "SpCCe1 holliday junction resolvase" NARROW [EC:3.1.22.4] +synonym: "SpCCe1 Holliday junction resolvase activity" NARROW [EC:3.1.22.-] +xref: EC:3.1.22.4 +xref: MetaCyc:3.1.22.4-RXN +is_a: GO:0016889 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0008822 +name: obsolete crotonobetaine/carnitine-CoA ligase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a bifunctional gene product. +synonym: "crotonobetaine/carnitine-CoA ligase activity" EXACT [] +is_obsolete: true +consider: GO:0051108 +consider: GO:0051109 + +[Term] +id: GO:0008823 +name: cupric reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH." [PMID:10510271] +xref: EC:1.16.1 +xref: MetaCyc:R170-RXN +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0008824 +name: cyanate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanate + H2O = carbamate." [EC:4.2.1.104, RHEA:11120] +comment: Note that this function was formerly EC:4.3.99.1. +synonym: "carbamate hydro-lyase activity" EXACT [EC:4.2.1.104] +synonym: "cyanase activity" EXACT [] +synonym: "cyanate aminohydrolase activity" EXACT [EC:4.2.1.104] +synonym: "cyanate C-N-lyase activity" EXACT [EC:4.2.1.104] +synonym: "cyanate hydrolase activity" EXACT [EC:4.2.1.104] +synonym: "cyanate lyase activity" EXACT [] +xref: EC:4.2.1.104 +xref: MetaCyc:R524-RXN +xref: RHEA:11120 +xref: UM-BBD_reactionID:r0608 +is_a: GO:0016840 ! carbon-nitrogen lyase activity + +[Term] +id: GO:0008825 +name: cyclopropane-fatty-acyl-phospholipid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid." [EC:2.1.1.79] +synonym: "CFA synthase activity" EXACT [EC:2.1.1.79] +synonym: "cyclopropane fatty acid synthase activity" EXACT [EC:2.1.1.79] +synonym: "cyclopropane fatty acid synthetase activity" EXACT [EC:2.1.1.79] +synonym: "cyclopropane synthase activity" EXACT [EC:2.1.1.79] +synonym: "cyclopropane synthetase activity" BROAD [EC:2.1.1.79] +synonym: "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)" EXACT [EC:2.1.1.79] +synonym: "unsaturated-phospholipid methyltransferase activity" BROAD [EC:2.1.1.79] +xref: EC:2.1.1.79 +xref: MetaCyc:2.1.1.79-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0008826 +name: cysteine sulfinate desulfinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite." [MetaCyc:RXN0-279] +synonym: "cysteine sulphinate desulphinase activity" EXACT [] +xref: EC:4.4.1 +xref: MetaCyc:RXN0-279 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0008827 +name: cytochrome o ubiquinol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2O; cytochrome O is the electron acceptor." [GOC:mah, MetaCyc:CYT-UBIQUINOL-OXID-RXN] +xref: EC:1.10.3 +is_a: GO:0015002 ! heme-copper terminal oxidase activity +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0008828 +name: dATP pyrophosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate." [RHEA:31583] +xref: EC:3.6.1.56 +xref: MetaCyc:RXN0-384 +xref: RHEA:31583 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity + +[Term] +id: GO:0008829 +name: dCTP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCTP + H2O = dUTP + NH3." [EC:3.5.4.13] +synonym: "5-methyl-dCTP deaminase activity" EXACT [EC:3.5.4.13] +synonym: "dCTP aminohydrolase activity" EXACT [EC:3.5.4.13] +synonym: "deoxycytidine triphosphate deaminase activity" EXACT [EC:3.5.4.13] +xref: EC:3.5.4.13 +xref: MetaCyc:DCTP-DEAM-RXN +xref: Reactome:R-HSA-180632 "Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand" +xref: RHEA:22680 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0008830 +name: dTDP-4-dehydrorhamnose 3,5-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose." [EC:5.1.3.13, RHEA:16969] +synonym: "dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity" EXACT [EC:5.1.3.13] +synonym: "dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity" EXACT [EC:5.1.3.13] +synonym: "TDP-4-keto-L-rhamnose-3,5-epimerase activity" EXACT [EC:5.1.3.13] +synonym: "TDP-4-ketorhamnose 3,5-epimerase activity" EXACT [EC:5.1.3.13] +synonym: "thymidine diphospho-4-ketorhamnose 3,5-epimerase activity" RELATED [EC:5.1.3.13] +xref: EC:5.1.3.13 +xref: KEGG_REACTION:R06514 +xref: MetaCyc:DTDPDEHYDRHAMEPIM-RXN +xref: RHEA:16969 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0008831 +name: dTDP-4-dehydrorhamnose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH." [EC:1.1.1.133, RHEA:21796] +synonym: "dTDP-4-keto-L-rhamnose reductase activity" EXACT [EC:1.1.1.133] +synonym: "dTDP-4-ketorhamnose reductase activity" EXACT [EC:1.1.1.133] +synonym: "dTDP-6-deoxy-L-mannose dehydrogenase activity" EXACT [EC:1.1.1.133] +synonym: "dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.133] +synonym: "reductase, thymidine diphospho-4-ketorhamnose" EXACT [EC:1.1.1.133] +synonym: "TDP-4-keto-rhamnose reductase activity" EXACT [EC:1.1.1.133] +synonym: "thymidine diphospho-4-ketorhamnose reductase activity" EXACT [EC:1.1.1.133] +xref: EC:1.1.1.133 +xref: KEGG_REACTION:R02777 +xref: MetaCyc:DTDPDEHYRHAMREDUCT-RXN +xref: RHEA:21796 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008832 +name: dGTPase activity +namespace: molecular_function +def: "Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate." [EC:3.1.5.1, RHEA:15193] +synonym: "deoxy-GTPase activity" EXACT [EC:3.1.5.1] +synonym: "deoxyguanosine 5-triphosphate triphosphohydrolase activity" EXACT [EC:3.1.5.1] +synonym: "deoxyguanosine triphosphatase activity" EXACT [EC:3.1.5.1] +synonym: "deoxyguanosine triphosphate triphosphohydrolase activity" EXACT [EC:3.1.5.1] +synonym: "deoxyguanosinetriphosphate triphosphohydrolase activity" EXACT [] +synonym: "dGTP triphosphohydrolase activity" EXACT [EC:3.1.5.1] +xref: EC:3.1.5.1 +xref: KEGG_REACTION:R01856 +xref: MetaCyc:DGTPTRIPHYDRO-RXN +xref: RHEA:15193 +is_a: GO:0016793 ! triphosphoric monoester hydrolase activity + +[Term] +id: GO:0008833 +name: deoxyribonuclease IV (phage-T4-induced) activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products." [EC:3.1.21.2] +synonym: "deoxriboendonuclease activity" EXACT [EC:3.1.21.2] +synonym: "deoxyribonuclease IV (phage T4-induced) activity" EXACT [EC:3.1.21.2] +synonym: "DNA-adenine-transferase activity" EXACT [EC:3.1.21.2] +synonym: "E. coli endonuclease IV" RELATED [EC:3.1.21.2] +synonym: "endodeoxyribonuclease IV (phage T(4)-induced) activity" EXACT [EC:3.1.21.2] +synonym: "endodeoxyribonuclease IV (phage T4-induced) activity" EXACT [EC:3.1.21.2] +synonym: "endonuclease II" RELATED [EC:3.1.21.2] +synonym: "endonuclease IV activity" RELATED [EC:3.1.21.2] +synonym: "Escherichia coli endonuclease II" RELATED [EC:3.1.21.2] +synonym: "redoxyendonuclease activity" EXACT [EC:3.1.21.2] +xref: EC:3.1.21.2 +xref: MetaCyc:3.1.21.2-RXN +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008834 +name: di-trans,poly-cis-decaprenylcistransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate." [EC:2.5.1.31] +synonym: "bactoprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31] +synonym: "di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity" EXACT [EC:2.5.1.31] +synonym: "di-trans,poly-cis-undecaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.31] +synonym: "undecaprenyl diphosphate synthase activity" EXACT [] +synonym: "undecaprenyl diphosphate synthetase activity" EXACT [EC:2.5.1.31] +synonym: "undecaprenyl pyrophosphate synthase activity" EXACT [EC:2.5.1.31] +synonym: "undecaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.31] +synonym: "undecaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.31] +synonym: "UPP synthetase activity" EXACT [EC:2.5.1.31] +xref: EC:2.5.1.31 +xref: MetaCyc:RXN-8999 +xref: RHEA:27551 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0008835 +name: diaminohydroxyphosphoribosylaminopyrimidine deaminase activity +namespace: molecular_function +alt_id: GO:0008485 +def: "Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+)." [EC:3.5.4.26, RHEA:21868] +synonym: "2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity" EXACT [] +synonym: "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity" EXACT [EC:3.5.4.26] +synonym: "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity" EXACT [EC:3.5.4.26] +xref: EC:3.5.4.26 +xref: KEGG_REACTION:R03459 +xref: MetaCyc:RIBOFLAVINSYNDEAM-RXN +xref: RHEA:21868 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0008836 +name: diaminopimelate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2)." [EC:4.1.1.20, RHEA:15101] +synonym: "DAP decarboxylase activity" EXACT [EC:4.1.1.20] +synonym: "DAP-decarboxylase activity" EXACT [EC:4.1.1.20] +synonym: "diaminopimelic acid decarboxylase activity" EXACT [EC:4.1.1.20] +synonym: "meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)" EXACT [EC:4.1.1.20] +synonym: "meso-2,6-diaminoheptanedioate carboxy-lyase activity" EXACT [EC:4.1.1.20] +synonym: "meso-diaminopimelate decarboxylase activity" EXACT [EC:4.1.1.20] +xref: EC:4.1.1.20 +xref: KEGG_REACTION:R00451 +xref: MetaCyc:DIAMINOPIMDECARB-RXN +xref: RHEA:15101 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008837 +name: diaminopimelate epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate." [EC:5.1.1.7, RHEA:15393] +synonym: "LL-2,6-diaminoheptanedioate 2-epimerase activity" EXACT [EC:5.1.1.7] +xref: EC:5.1.1.7 +xref: KEGG_REACTION:R02735 +xref: MetaCyc:DIAMINOPIMEPIM-RXN +xref: RHEA:15393 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0008838 +name: diaminopropionate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3." [EC:4.3.1.15] +synonym: "2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming)" EXACT [EC:4.3.1.15] +synonym: "2,3-diaminopropionate ammonia-lyase activity" EXACT [EC:4.3.1.15] +synonym: "alpha,beta-diaminopropionate ammonia-lyase activity" EXACT [EC:4.3.1.15] +synonym: "diaminopropionatase activity" EXACT [EC:4.3.1.15] +xref: EC:4.3.1.15 +xref: MetaCyc:4.3.1.15-RXN +xref: RHEA:22084 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0008839 +name: 4-hydroxy-tetrahydrodipicolinate reductase +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+." [EC:1.17.1.8] +synonym: "2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.26] +synonym: "dihydrodipicolinate reductase activity" EXACT [] +synonym: "dihydrodipicolinic acid reductase activity" EXACT [EC:1.3.1.26] +xref: EC:1.17.1.8 +xref: MetaCyc:DIHYDROPICRED-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008840 +name: 4-hydroxy-tetrahydrodipicolinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O." [EC:4.3.3.7, RHEA:14845] +synonym: "DHDPS activity" EXACT [EC:4.2.1.52] +synonym: "dihydrodipicolinate synthase activity" EXACT [] +synonym: "dihydrodipicolinate synthetase activity" EXACT [EC:4.2.1.52] +synonym: "dihydrodipicolinic acid synthase activity" EXACT [EC:4.2.1.52] +synonym: "dihydropicolinate synthetase activity" EXACT [EC:4.2.1.52] +synonym: "L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)" EXACT [EC:4.2.1.52] +synonym: "L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]" RELATED [EC:4.2.1.52] +xref: EC:4.3.3.7 +xref: KEGG_REACTION:R02292 +xref: MetaCyc:DIHYDRODIPICSYN-RXN +xref: RHEA:14845 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008841 +name: dihydrofolate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate." [EC:6.3.2.12] +synonym: "7,8-dihydrofolate synthetase activity" EXACT [EC:6.3.2.12] +synonym: "7,8-dihydropteroate:L-glutamate ligase (ADP) activity" EXACT [EC:6.3.2.12] +synonym: "7,8-dihydropteroate:L-glutamate ligase (ADP-forming)" EXACT [EC:6.3.2.12] +synonym: "DHFS activity" EXACT [EC:6.3.2.12] +synonym: "dihydrofolate synthetase activity" EXACT [EC:6.3.2.12] +synonym: "dihydrofolate synthetase-folylpolyglutamate synthetase activity" EXACT [EC:6.3.2.12] +synonym: "dihydropteroate:L-glutamate ligase (ADP-forming) activity" EXACT [EC:6.3.2.12] +synonym: "FHFS activity" EXACT [EC:6.3.2.12] +synonym: "FHFS/FPGS activity" EXACT [EC:6.3.2.12] +synonym: "folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity" EXACT [EC:6.3.2.12] +synonym: "H(2)-folate synthetase activity" EXACT [EC:6.3.2.12] +synonym: "H2-folate synthetase activity" EXACT [EC:6.3.2.12] +xref: EC:6.3.2.12 +xref: MetaCyc:DIHYDROFOLATESYNTH-RXN +xref: RHEA:23584 +is_a: GO:0016881 ! acid-amino acid ligase activity +relationship: part_of GO:0006761 ! dihydrofolate biosynthetic process + +[Term] +id: GO:0008842 +name: diphosphate-purine nucleoside kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide." [EC:2.7.1.143] +synonym: "diphosphate-dependent nucleoside kinase activity" EXACT [EC:2.7.1.143] +synonym: "diphosphate:purine nucleoside phosphotransferase activity" EXACT [EC:2.7.1.143] +synonym: "pyrophosphate-dependent nucleoside kinase activity" EXACT [EC:2.7.1.143] +synonym: "pyrophosphate-purine nucleoside kinase activity" EXACT [EC:2.7.1.143] +xref: EC:2.7.1.143 +xref: MetaCyc:2.7.1.143-RXN +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019206 ! nucleoside kinase activity + +[Term] +id: GO:0008843 +name: endochitinase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain." [EC:3.2.1.-, GOC:bf, GOC:kah, GOC:pde, PMID:11468293] +is_a: GO:0004568 ! chitinase activity + +[Term] +id: GO:0008845 +name: obsolete endonuclease VIII activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [PMID:12713806] +comment: This term was made obsolete because it represents a gene product. +synonym: "endonuclease VIII activity" EXACT [] +is_obsolete: true +consider: GO:0000703 +consider: GO:0003684 +consider: GO:0003906 +consider: GO:0004519 +consider: GO:0008081 +consider: GO:0019104 + +[Term] +id: GO:0008846 +name: obsolete endopeptidase La activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP." [EC:3.4.21.53] +comment: This term was made obsolete because it represents a gene product. +synonym: "ATP-dependent lon proteinase" NARROW [EC:3.4.21.53] +synonym: "ATP-dependent protease La activity" EXACT [EC:3.4.21.53] +synonym: "ATP-dependent serine proteinase activity" RELATED [EC:3.4.21.53] +synonym: "endopeptidase La activity" EXACT [] +synonym: "Escherichia coli proteinase La" RELATED [EC:3.4.21.53] +synonym: "Escherichia coli serine proteinase La" RELATED [EC:3.4.21.53] +synonym: "gene lon protease activity" EXACT [EC:3.4.21.53] +synonym: "gene lon proteins" RELATED [EC:3.4.21.53] +synonym: "lon proteinase" NARROW [EC:3.4.21.53] +synonym: "PIM1 protease activity" EXACT [EC:3.4.21.53] +synonym: "PIM1 proteinase activity" EXACT [EC:3.4.21.53] +synonym: "protease La" RELATED [EC:3.4.21.53] +synonym: "proteinase La" RELATED [EC:3.4.21.53] +synonym: "serine protease La" RELATED [EC:3.4.21.53] +xref: EC:3.4.21.53 +xref: MetaCyc:3.4.21.53-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008847 +name: Enterobacter ribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:4.6.1.21] +synonym: "enterobacter ribonuclease activity" EXACT [EC:4.6.1.21] +synonym: "Enterobacter RNase activity" EXACT [] +xref: EC:4.6.1.21 +xref: MetaCyc:3.1.27.6-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0008848 +name: obsolete enterobactin synthetase +namespace: molecular_function +alt_id: GO:0008850 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a process rather than a function. +synonym: "enterobactin synthetase" EXACT [] +synonym: "enterochelin synthetase activity" EXACT [] +synonym: "nonribosomal peptide synthetase" RELATED [] +is_obsolete: true +replaced_by: GO:0009239 + +[Term] +id: GO:0008849 +name: enterochelin esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+." [MetaCyc:RXN0-1661, PMID:4565531] +synonym: "enterobactin esterase activity" EXACT [] +xref: MetaCyc:RXN0-1661 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0008851 +name: ethanolamine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethanolamine = acetaldehyde + NH3." [EC:4.3.1.7] +synonym: "ethanolamine ammonia-lyase (acetaldehyde-forming) activity" EXACT [EC:4.3.1.7] +synonym: "ethanolamine deaminase activity" EXACT [EC:4.3.1.7] +xref: EC:4.3.1.7 +xref: MetaCyc:ETHAMLY-RXN +xref: RHEA:15313 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0008852 +name: exodeoxyribonuclease I activity +namespace: molecular_function +def: "Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.1] +synonym: "E. coli exonuclease I" RELATED [EC:3.1.11.1] +synonym: "E. coli exonuclease I activity" NARROW [EC:3.1.11.1] +synonym: "Escherichia coli exonuclease I" RELATED [EC:3.1.11.1] +synonym: "exonuclease I activity" RELATED [EC:3.1.11.1] +xref: EC:3.1.11.1 +xref: MetaCyc:3.1.11.1-RXN +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008853 +name: exodeoxyribonuclease III activity +namespace: molecular_function +def: "Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.2] +synonym: "E. coli exonuclease III" RELATED [EC:3.1.11.2] +synonym: "E. coli exonuclease III activity" NARROW [EC:3.1.11.2] +synonym: "endoribonuclease III" RELATED [EC:3.1.11.2] +synonym: "Escherichia coli exonuclease III" RELATED [EC:3.1.11.2] +synonym: "exonuclease III activity" EXACT [EC:3.1.11.2] +xref: EC:3.1.11.2 +xref: MetaCyc:3.1.11.2-RXN +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008854 +name: exodeoxyribonuclease V activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides." [EC:3.1.11.5] +synonym: "E. coli exonuclease V" RELATED [EC:3.1.11.5] +synonym: "E. coli exonuclease V activity" NARROW [EC:3.1.11.5] +synonym: "Escherichia coli exonuclease V" RELATED [EC:3.1.11.5] +synonym: "exonuclease V activity" EXACT [EC:3.1.11.5] +synonym: "gene recBC DNase activity" EXACT [EC:3.1.11.5] +synonym: "gene recBC endoenzyme" RELATED [EC:3.1.11.5] +synonym: "gene recBCD enzymes" RELATED [EC:3.1.11.5] +synonym: "RecBC deoxyribonuclease activity" EXACT [EC:3.1.11.5] +xref: EC:3.1.11.5 +xref: MetaCyc:3.1.11.5-RXN +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008855 +name: exodeoxyribonuclease VII activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides." [EC:3.1.11.6] +synonym: "E. coli exonuclease VII" RELATED [EC:3.1.11.6] +synonym: "E. coli exonuclease VII activity" NARROW [EC:3.1.11.6] +synonym: "endodeoxyribonuclease VII" RELATED [EC:3.1.11.6] +synonym: "Escherichia coli exonuclease VII" RELATED [EC:3.1.11.6] +synonym: "exonuclease VII activity" EXACT [EC:3.1.11.6] +xref: EC:3.1.11.6 +xref: MetaCyc:3.1.11.6-RXN +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008856 +name: exodeoxyribonuclease X activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes." [EC:3.1.22.5] +synonym: "deoxyribonuclease X activity" EXACT [EC:3.1.22.5] +synonym: "Escherichia coli endodeoxyribonuclease activity" RELATED [EC:3.1.22.5] +synonym: "Escherichia coli endodeoxyribonuclease X activity" NARROW [EC:3.1.22.5] +xref: EC:3.1.11 +xref: MetaCyc:3.1.22.5-RXN +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008859 +name: exoribonuclease II activity +namespace: molecular_function +def: "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction." [EC:3.1.13.1, ISBN:0198547684] +synonym: "5'-exoribonuclease activity" EXACT [EC:3.1.13.1] +synonym: "BN ribonuclease activity" EXACT [EC:3.1.13.1] +synonym: "Escherichia coli exo-RNase II" RELATED [EC:3.1.13.1] +synonym: "ribonuclease II activity" EXACT [EC:3.1.13.1] +synonym: "ribonuclease Q" RELATED [EC:3.1.13.1] +synonym: "RNase II" RELATED [EC:3.1.13.1] +synonym: "RNase II activity" EXACT [] +xref: EC:3.1.13.1 +xref: MetaCyc:3.1.13.1-RXN +is_a: GO:0008408 ! 3'-5' exonuclease activity +is_a: GO:0016896 ! exoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0008860 +name: ferredoxin-NAD+ reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+." [EC:1.18.1.3] +synonym: "ferredoxin-linked NAD reductase activity" EXACT [EC:1.18.1.3] +synonym: "ferredoxin-NAD reductase activity" EXACT [] +synonym: "ferredoxin-nicotinamide adenine dinucleotide reductase activity" EXACT [EC:1.18.1.3] +synonym: "ferredoxin:NAD+ oxidoreductase activity" EXACT [EC:1.18.1.3] +synonym: "NAD-ferredoxin reductase activity" EXACT [EC:1.18.1.3] +synonym: "NADH flavodoxin oxidoreductase activity" EXACT [EC:1.18.1.3] +synonym: "NADH-ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.3] +synonym: "NADH-ferredoxin reductase activity" EXACT [EC:1.18.1.3] +synonym: "NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)" EXACT [EC:1.18.1.3] +synonym: "NADH-ferredoxinTOL reductase (component of toluene dioxygenase)" EXACT [EC:1.18.1.3] +synonym: "NADH2-ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.3] +synonym: "reductase, reduced nicotinamide adenine dinucleotide-ferredoxin" EXACT [EC:1.18.1.3] +xref: EC:1.18.1.3 +xref: MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN +is_a: GO:0008937 ! ferredoxin-NAD(P) reductase activity + +[Term] +id: GO:0008861 +name: formate C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate." [EC:2.3.1.54] +synonym: "acetyl-CoA:formate C-acetyltransferase activity" EXACT [EC:2.3.1.54] +synonym: "formate acetyltransferase activity" EXACT [EC:2.3.1.54] +synonym: "PFL" EXACT [] +synonym: "pyruvate formate-lyase activity" EXACT [EC:2.3.1.54] +synonym: "pyruvate formate:lyase activity" EXACT [] +synonym: "pyruvic formate-lyase activity" EXACT [EC:2.3.1.54] +xref: EC:2.3.1.54 +xref: MetaCyc:PYRUVFORMLY-RXN +xref: RHEA:11844 +is_a: GO:0016453 ! C-acetyltransferase activity + +[Term] +id: GO:0008863 +name: formate dehydrogenase (NAD+) activity +namespace: molecular_function +alt_id: GO:0018476 +def: "Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH." [EC:1.17.1.9, RHEA:15985] +synonym: "FDH I" RELATED [EC:1.17.1.9] +synonym: "FDH II" RELATED [EC:1.17.1.9] +synonym: "formate benzyl-viologen oxidoreductase" EXACT [EC:1.17.1.9] +synonym: "formate dehydrogenase (NAD)" EXACT [EC:1.17.1.9] +synonym: "formate hydrogenlyase" EXACT [EC:1.17.1.9] +synonym: "formate-NAD oxidoreductase" EXACT [EC:1.17.1.9] +synonym: "formate:NAD+ oxidoreductase" EXACT [EC:1.17.1.9] +synonym: "formic acid dehydrogenase" EXACT [EC:1.17.1.9] +synonym: "formic hydrogen-lyase" EXACT [EC:1.17.1.9] +synonym: "N-FDH" RELATED [EC:1.17.1.9] +synonym: "NAD-dependent formate dehydrogenase" EXACT [EC:1.17.1.9] +synonym: "NAD-formate dehydrogenase" EXACT [EC:1.17.1.9] +synonym: "NAD-linked formate dehydrogenase" EXACT [EC:1.17.1.9] +xref: EC:1.17.1.9 +xref: KEGG_REACTION:R00519 +xref: MetaCyc:1.2.1.2-RXN +xref: MetaCyc:FORMATEDEHYDROG-RXN +xref: RHEA:15985 +xref: UM-BBD_reactionID:r0103 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008864 +name: formyltetrahydrofolate deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)." [EC:3.5.1.10, RHEA:19833] +synonym: "10-formyltetrahydrofolate amidohydrolase activity" EXACT [EC:3.5.1.10] +synonym: "formyl-FH(4) hydrolase activity" EXACT [EC:3.5.1.10] +synonym: "formyltetrahydrofolate hydrolase activity" EXACT [EC:3.5.1.10] +xref: EC:3.5.1.10 +xref: KEGG_REACTION:R00944 +xref: MetaCyc:FORMYLTHFDEFORMYL-RXN +xref: RHEA:19833 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008865 +name: fructokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate." [EC:2.7.1.4] +synonym: "ATP:D-fructose 6-phosphotransferase activity" EXACT [EC:2.7.1.4] +synonym: "D-fructokinase activity" EXACT [EC:2.7.1.4] +synonym: "D-fructose(D-mannose)kinase activity" EXACT [EC:2.7.1.4] +synonym: "fructokinase (phosphorylating)" EXACT [EC:2.7.1.4] +xref: EC:2.7.1.4 +xref: MetaCyc:FRUCTOKINASE-RXN +xref: RHEA:16125 +is_a: GO:0004396 ! hexokinase activity + +[Term] +id: GO:0008866 +name: fructuronate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH." [EC:1.1.1.57, RHEA:15729] +synonym: "D-mannonate dehydrogenase activity" EXACT [EC:1.1.1.57] +synonym: "D-mannonate oxidoreductase activity" EXACT [EC:1.1.1.57] +synonym: "D-mannonate:NAD oxidoreductase activity" EXACT [EC:1.1.1.57] +synonym: "D-mannonate:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.57] +synonym: "mannonate oxidoreductase activity" EXACT [EC:1.1.1.57] +synonym: "mannonic dehydrogenase activity" EXACT [EC:1.1.1.57] +xref: EC:1.1.1.57 +xref: KEGG_REACTION:R02454 +xref: MetaCyc:MANNONOXIDOREDUCT-RXN +xref: RHEA:15729 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008867 +name: galactarate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O." [EC:4.2.1.42, RHEA:16005] +synonym: "D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)" EXACT [EC:4.2.1.42] +synonym: "D-galactarate hydro-lyase activity" EXACT [EC:4.2.1.42] +xref: EC:4.2.1.42 +xref: KEGG_REACTION:R05608 +xref: MetaCyc:GALACTARDEHYDRA-RXN +xref: RHEA:16005 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008868 +name: galactitol-1-phosphate 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+." [EC:1.1.1.251] +synonym: "galactitol-1-phosphate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.251] +xref: EC:1.1.1.251 +xref: MetaCyc:1.1.1.251-RXN +xref: RHEA:15137 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008869 +name: galactonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O." [EC:4.2.1.6, RHEA:18649] +synonym: "D-galactonate dehydrase activity" EXACT [EC:4.2.1.6] +synonym: "D-galactonate dehydratase activity" EXACT [EC:4.2.1.6] +synonym: "D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)" EXACT [EC:4.2.1.6] +synonym: "D-galactonate hydro-lyase activity" EXACT [EC:4.2.1.6] +xref: EC:4.2.1.6 +xref: KEGG_REACTION:R03033 +xref: MetaCyc:GALACTONDEHYDRAT-RXN +xref: RHEA:18649 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008870 +name: galactoside O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside." [EC:2.3.1.18] +synonym: "acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity" EXACT [EC:2.3.1.18] +synonym: "galactoside acetyltransferase activity" EXACT [EC:2.3.1.18] +synonym: "thiogalactoside acetyltransferase activity" EXACT [EC:2.3.1.18] +synonym: "thiogalactoside transacetylase activity" EXACT [EC:2.3.1.18] +xref: EC:2.3.1.18 +xref: MetaCyc:GALACTOACETYLTRAN-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0008871 +name: aminoglycoside 2''-nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside." [EC:2.7.7.46, GOC:cb] +synonym: "2''-aminoglycoside nucleotidyltransferase activity" EXACT [EC:2.7.7.46] +synonym: "gentamicin 2''- adenylyltransferase activity" NARROW [EC:2.7.7.46] +synonym: "gentamicin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] +synonym: "gentamycin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] +synonym: "NTP:gentamicin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] +xref: EC:2.7.7.46 +xref: MetaCyc:2.7.7.46-RXN +is_a: GO:0034068 ! aminoglycoside nucleotidyltransferase activity + +[Term] +id: GO:0008872 +name: glucarate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O." [EC:4.2.1.40] +synonym: "D-glucarate dehydratase activity" EXACT [EC:4.2.1.40] +synonym: "D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)" EXACT [EC:4.2.1.40] +synonym: "D-glucarate hydro-lyase activity" EXACT [EC:4.2.1.40] +xref: EC:4.2.1.40 +xref: MetaCyc:GLUCARDEHYDRA-RXN +xref: RHEA:14573 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008873 +name: gluconate 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215] +synonym: "2-keto-D-gluconate reductase activity" EXACT [EC:1.1.1.215] +synonym: "2-ketogluconate reductase activity" EXACT [EC:1.1.1.215] +synonym: "D-gluconate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.215] +xref: EC:1.1.1.215 +xref: MetaCyc:1.1.1.215-RXN +xref: RHEA:16653 +is_a: GO:0008875 ! gluconate dehydrogenase activity + +[Term] +id: GO:0008874 +name: gluconate 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.69] +synonym: "5-keto-D-gluconate 5-reductase activity" EXACT [EC:1.1.1.69] +synonym: "5-keto-D-gluconate reductase" EXACT [EC:1.1.1.69] +synonym: "5-ketogluconate 5-reductase activity" EXACT [EC:1.1.1.69] +synonym: "5-ketogluconate reductase activity" EXACT [EC:1.1.1.69] +synonym: "D-gluconate:NAD(P)+ 5-oxidoreductase" EXACT [EC:1.1.1.69] +xref: EC:1.1.1.69 +xref: MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN +is_a: GO:0008875 ! gluconate dehydrogenase activity + +[Term] +id: GO:0008875 +name: gluconate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215, EC:1.1.1.69] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008876 +name: quinoprotein glucose dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol." [EC:1.1.5.2] +comment: Note that this was EC:1.1.99.17. +synonym: "D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity" EXACT [EC:1.1.5.2] +synonym: "D-glucose:ubiquinone oxidoreductase activity" EXACT [EC:1.1.5.2] +synonym: "glucose dehydrogenase (PQQ-dependent) activity" EXACT [EC:1.1.5.2] +synonym: "glucose dehydrogenase (pyrroloquinoline-quinone) activity" EXACT [] +synonym: "quinoprotein D-glucose dehydrogenase activity" EXACT [EC:1.1.5.2] +xref: EC:1.1.5.2 +xref: MetaCyc:GLUCDEHYDROG-RXN +xref: RHEA:22152 +is_a: GO:0004344 ! glucose dehydrogenase activity +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0008877 +name: glucose-1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate." [EC:3.1.3.10] +synonym: "alpha-D-glucose-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.10] +synonym: "D-glucose-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.10] +xref: EC:3.1.3.10 +xref: KEGG_REACTION:R00304 +xref: MetaCyc:GLUCOSE-1-PHOSPHAT-RXN +xref: RHEA:19933 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0008878 +name: glucose-1-phosphate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate." [EC:2.7.7.27, RHEA:12120] +synonym: "adenosine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] +synonym: "adenosine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] +synonym: "ADGase activity" EXACT [] +synonym: "ADP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] +synonym: "ADP-glucose diphosphorylase activity" EXACT [EC:2.7.7.27] +synonym: "ADP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] +synonym: "ADP-glucose synthase activity" EXACT [EC:2.7.7.27] +synonym: "ADP-glucose synthetase activity" EXACT [EC:2.7.7.27] +synonym: "ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] +synonym: "ADPG pyrophosphorylase activity" EXACT [] +synonym: "ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] +synonym: "ATP:alpha-glucose-1-phosphate adenylyl transferase activity" EXACT [] +synonym: "glucose 1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] +xref: EC:2.7.7.27 +xref: KEGG_REACTION:R00948 +xref: MetaCyc:GLUC1PADENYLTRANS-RXN +xref: RHEA:12120 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0008879 +name: glucose-1-phosphate thymidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose." [EC:2.7.7.24, RHEA:15225] +synonym: "dTDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.24] +synonym: "dTDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] +synonym: "dTDP-glucose synthase activity" EXACT [EC:2.7.7.24] +synonym: "dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.24] +synonym: "glucose 1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.24] +synonym: "TDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] +synonym: "thymidine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] +synonym: "thymidine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] +xref: EC:2.7.7.24 +xref: KEGG_REACTION:R02328 +xref: MetaCyc:DTDPGLUCOSEPP-RXN +xref: RHEA:15225 +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0008880 +name: glucuronate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucuronate = D-fructuronate." [EC:5.3.1.12] +synonym: "D-glucuronate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.12] +synonym: "D-glucuronate isomerase activity" EXACT [EC:5.3.1.12] +synonym: "D-glucuronate ketol-isomerase activity" EXACT [EC:5.3.1.12] +synonym: "uronate isomerase activity" EXACT [EC:5.3.1.12] +synonym: "uronic acid isomerase activity" EXACT [EC:5.3.1.12] +synonym: "uronic isomerase activity" EXACT [EC:5.3.1.12] +xref: EC:5.3.1.12 +xref: MetaCyc:GLUCUROISOM-RXN +xref: RHEA:13049 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008881 +name: glutamate racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate = D-glutamate." [EC:5.1.1.3, RHEA:12813] +xref: EC:5.1.1.3 +xref: KEGG_REACTION:R00260 +xref: MetaCyc:GLUTRACE-RXN +xref: RHEA:12813 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0008882 +name: [glutamate-ammonia-ligase] adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]." [EC:2.7.7.42] +synonym: "adenosine triphosphate:glutamine synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] +synonym: "ATP:[glutamate-ammonia-ligase] adenylyltransferase activity" EXACT [] +synonym: "ATP:glutamine synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] +synonym: "ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity" EXACT [EC:2.7.7.42] +synonym: "glutamate-ammonia-ligase adenylyltransferase activity" EXACT [] +synonym: "glutamine-synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] +xref: EC:2.7.7.42 +xref: MetaCyc:GSADENYLATION-RXN +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0008883 +name: glutamyl-tRNA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH." [EC:1.2.1.70, RHEA:12344] +synonym: "L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)" EXACT [EC:1.2.1.70] +xref: EC:1.2.1.70 +xref: KEGG_REACTION:R04109 +xref: MetaCyc:GLUTRNAREDUCT-RXN +xref: RHEA:12344 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0008884 +name: glutathionylspermidine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine." [EC:3.5.1.78] +synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity" EXACT [EC:3.5.1.78] +synonym: "glutathionylspermidine amidohydrolase (spermidine-forming) activity" EXACT [EC:3.5.1.78] +synonym: "GSP amidase activity" EXACT [EC:3.5.1.78] +xref: EC:3.5.1.78 +xref: MetaCyc:GSPAMID-RXN +xref: RHEA:17173 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008885 +name: glutathionylspermidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate." [EC:6.3.1.8] +synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]" RELATED [EC:6.3.1.8] +synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity" EXACT [EC:6.3.1.8] +synonym: "glutathione:spermidine ligase (ADP-forming) activity" EXACT [EC:6.3.1.8] +synonym: "glutathionylspermidine synthetase activity" EXACT [EC:6.3.1.8] +synonym: "GSP synthetase activity" EXACT [EC:6.3.1.8] +xref: EC:6.3.1.8 +xref: MetaCyc:GSPSYN-RXN +xref: RHEA:21272 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0008886 +name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH." [EC:1.2.1.9, RHEA:14669] +synonym: "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity" EXACT [] +synonym: "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)" BROAD [] +synonym: "glyceraldehyde 3-phosphate dehydrogenase (NADP)" EXACT [] +synonym: "glyceraldehyde phosphate dehydrogenase (NADP)" BROAD [] +synonym: "glyceraldehyde-3-phosphate dehydrogenase (NADP)" EXACT [] +synonym: "glyceraldehyde-3-phosphate:NADP reductase activity" EXACT [] +synonym: "NADP-glyceraldehyde phosphate dehydrogenase" BROAD [] +synonym: "NADP-glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] +synonym: "nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] +synonym: "triosephosphate dehydrogenase activity" BROAD [EC:1.2.1.9] +xref: EC:1.2.1.9 +xref: KEGG_REACTION:R01058 +xref: MetaCyc:1.2.1.9-RXN +xref: RHEA:14669 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008887 +name: glycerate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+)." [EC:2.7.1.31, RHEA:23516] +synonym: "ATP:(R)-glycerate 3-phosphotransferase activity" EXACT [EC:2.7.1.31] +synonym: "ATP:D-glycerate 2-phosphotransferase activity" EXACT [EC:2.7.1.31] +synonym: "D-glycerate 3-kinase activity" EXACT [EC:2.7.1.31] +synonym: "D-glycerate kinase activity" EXACT [EC:2.7.1.31] +synonym: "D-glyceric acid kinase activity" EXACT [EC:2.7.1.31] +synonym: "GK" RELATED [EC:2.7.1.31] +synonym: "glycerate kinase (phosphorylating)" EXACT [EC:2.7.1.31] +synonym: "glycerate-3-kinase activity" EXACT [EC:2.7.1.31] +xref: EC:2.7.1.31 +xref: KEGG_REACTION:R01514 +xref: MetaCyc:GLY3KIN-RXN +xref: Reactome:R-HSA-6799495 "GLYCTK phosphorylates DGA to 3PDGA" +xref: RHEA:23516 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008888 +name: glycerol dehydrogenase [NAD+] activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH." [EC:1.1.1.6, RHEA:13769] +synonym: "glycerol dehydrogenase activity" BROAD [] +synonym: "NAD-linked glycerol dehydrogenase activity" EXACT [EC:1.1.1.6] +xref: EC:1.1.1.6 +xref: KEGG_REACTION:R01034 +xref: MetaCyc:GLYCDEH-RXN +xref: RHEA:13769 +is_a: GO:1990042 ! glycerol dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0008889 +name: glycerophosphodiester phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate." [EC:3.1.4.46] +synonym: "gene hpd protein" RELATED [EC:3.1.4.46] +synonym: "glycerophosphodiester glycerophosphohydrolase activity" EXACT [EC:3.1.4.46] +synonym: "glycerophosphoryl diester phosphodiesterase activity" EXACT [EC:3.1.4.46] +synonym: "IgD-binding protein D" RELATED [EC:3.1.4.46] +xref: EC:3.1.4.46 +xref: MetaCyc:GLYCPDIESTER-RXN +xref: Reactome:R-HSA-1483107 "GPETA is hydrolyzed to ETA and G3P by GPCPD1" +xref: Reactome:R-HSA-1483116 "GPCho is hydrolyzed to Cho and G3P by GPCPD1" +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0008890 +name: glycine C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+)." [EC:2.3.1.29, RHEA:20736] +synonym: "2-amino-3-ketobutyrate CoA ligase activity" EXACT [EC:2.3.1.29] +synonym: "2-amino-3-ketobutyrate coenzyme A ligase activity" EXACT [EC:2.3.1.29] +synonym: "2-amino-3-ketobutyrate-CoA ligase activity" EXACT [EC:2.3.1.29] +synonym: "acetyl-CoA:glycine C-acetyltransferase activity" EXACT [EC:2.3.1.29] +synonym: "aminoacetone synthase activity" EXACT [EC:2.3.1.29] +synonym: "glycine acetyltransferase activity" EXACT [EC:2.3.1.29] +xref: EC:2.3.1.29 +xref: KEGG_REACTION:R00371 +xref: MetaCyc:AKBLIG-RXN +xref: RHEA:20736 +is_a: GO:0016453 ! C-acetyltransferase activity + +[Term] +id: GO:0008891 +name: glycolate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide." [EC:1.1.3.15] +xref: MetaCyc:RXN-969 +xref: Reactome:R-HSA-389842 "HAO1 tetramer oxidizes glycolate to glyoxylate" +is_a: GO:0003973 ! (S)-2-hydroxy-acid oxidase activity + +[Term] +id: GO:0008892 +name: guanine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanine + H2O = xanthine + NH3." [EC:3.5.4.3] +synonym: "GAH activity" EXACT [EC:3.5.4.3] +synonym: "guanase activity" EXACT [EC:3.5.4.3] +synonym: "guanine aminase activity" EXACT [EC:3.5.4.3] +synonym: "guanine aminohydrolase activity" EXACT [EC:3.5.4.3] +xref: EC:3.5.4.3 +xref: MetaCyc:GUANINE-DEAMINASE-RXN +xref: Reactome:R-HSA-74255 "Guanine + H2O => Xanthine + NH4+" +xref: RHEA:14665 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0008893 +name: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate." [EC:3.1.7.2] +synonym: "(ppGpp)ase activity" EXACT [EC:3.1.7.2] +synonym: "guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity" EXACT [] +synonym: "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity" EXACT [EC:3.1.7.2] +synonym: "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity" EXACT [] +synonym: "penta-phosphate guanosine-3'-diphosphohydrolase activity" EXACT [EC:3.1.7.2] +synonym: "penta-phosphate guanosine-3'-pyrophosphohydrolase activity" EXACT [EC:3.1.7.2] +synonym: "PpGpp phosphohydrolase activity" EXACT [EC:3.1.7.2] +synonym: "PpGpp-3'-pyrophosphohydrolase activity" EXACT [EC:3.1.7.2] +xref: EC:3.1.7.2 +xref: MetaCyc:PPGPPSYN-RXN +xref: RHEA:14253 +is_a: GO:0016794 ! diphosphoric monoester hydrolase activity + +[Term] +id: GO:0008894 +name: guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate." [EC:3.6.1.40] +synonym: "guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine pentaphosphatase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine pentaphosphate phosphatase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine pentaphosphate phosphohydrolase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] +synonym: "guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity" EXACT [] +synonym: "pppGpp 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] +xref: EC:3.6.1.40 +xref: MetaCyc:PPPGPPHYDRO-RXN +xref: RHEA:13073 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0008897 +name: holo-[acyl-carrier-protein] synthase activity +namespace: molecular_function +alt_id: GO:0008958 +def: "Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form." [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709] +synonym: "4'-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] +synonym: "4'-phosphopantetheinyltransferase activity" EXACT [] +synonym: "AcpS" RELATED [EC:2.7.8.7] +synonym: "ACPS activity" RELATED [EC:2.7.8.7] +synonym: "acyl carrier protein holoprotein (holo-ACP) synthetase activity" EXACT [EC:2.7.8.7] +synonym: "acyl carrier protein synthase activity" RELATED [EC:2.7.8.7] +synonym: "acyl carrier protein synthetase activity" RELATED [EC:2.7.8.7] +synonym: "alpha-aminoadipate reductase phosphopantetheinyl transferase activity" EXACT [] +synonym: "alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] +synonym: "alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] +synonym: "CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity" EXACT [EC:2.7.8.7] +synonym: "CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity" EXACT [EC:2.7.8.7] +synonym: "coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity" EXACT [EC:2.7.8.7] +synonym: "holo-[acyl-carrier-protein] synthase activity" NARROW [] +synonym: "holo-[peptidyl-carrier protein] synthase activity" NARROW [] +synonym: "holo-ACP synthase activity" RELATED [EC:2.7.8.7] +synonym: "holo-ACP synthetase activity" RELATED [EC:2.7.8.7] +synonym: "holo-acyl-carrier-protein synthase activity" EXACT [EC:2.7.8.7] +synonym: "holosynthase activity" RELATED [EC:2.7.8.7] +synonym: "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" NARROW [EC:2.7.8.7] +synonym: "P-pant transferase activity" EXACT [EC:2.7.8.7] +synonym: "phosphopantetheinyl transferase" RELATED [] +synonym: "phosphopantetheinyltransferase activity" EXACT [] +synonym: "PPTase activity" EXACT [EC:2.7.8.7] +xref: EC:2.7.8.7 +xref: MetaCyc:HOLO-ACP-SYNTH-RXN +xref: Reactome:R-HSA-199202 "Phosphopantetheine conjugation of the ACP domain of FAS" +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0008898 +name: S-adenosylmethionine-homocysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine." [EC:2.1.1.10, GOC:BHF, GOC:dph] +synonym: "adenosylmethionine transmethylase activity" EXACT [EC:2.1.1.10] +synonym: "adenosylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] +synonym: "homocysteine methyltransferase activity" RELATED [EC:2.1.1.10] +synonym: "homocysteine transmethylase activity" RELATED [EC:2.1.1.10] +synonym: "L-homocysteine S-methyltransferase activity" RELATED [EC:2.1.1.10] +synonym: "S-adenosyl-L-methionine:L-homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] +synonym: "S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.10] +synonym: "S-adenosylmethionine homocysteine transmethylase activity" EXACT [EC:2.1.1.10] +synonym: "S-adenosylmethionine-homocysteine transmethylase activity" EXACT [EC:2.1.1.10] +synonym: "S-adenosylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] +xref: MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN +xref: RHEA:21820 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0008899 +name: homoserine O-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA." [EC:2.3.1.46, RHEA:22008] +synonym: "homoserine O-transsuccinylase activity" BROAD [EC:2.3.1.46] +synonym: "homoserine succinyltransferase activity" EXACT [EC:2.3.1.46] +synonym: "succinyl-CoA:L-homoserine O-succinyltransferase activity" EXACT [EC:2.3.1.46] +xref: EC:2.3.1.46 +xref: KEGG_REACTION:R01777 +xref: MetaCyc:HOMSUCTRAN-RXN +xref: RHEA:22008 +is_a: GO:0016750 ! O-succinyltransferase activity + +[Term] +id: GO:0008900 +name: potassium:proton exchanging ATPase activity +namespace: molecular_function +alt_id: GO:0005390 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in)." [EC:7.2.2.19] +synonym: "(K+ + H+)-ATPase activity" EXACT [EC:7.2.2.19] +synonym: "ATP phosphohydrolase (H+/K+-exchanging)" EXACT [EC:7.2.2.19] +synonym: "gastric H(+)/K(+) ATPase activity" NARROW [EC:3.6.3.10] +synonym: "gastric H+/K+ ATPase" NARROW [EC:7.2.2.19] +synonym: "H(+)/K(+)-ATPase activity" EXACT [EC:7.2.2.19] +synonym: "H(+)/K(+)-exchanging ATPase activity" EXACT [EC:7.2.2.19] +synonym: "H+-K+-ATPase activity" EXACT [EC:7.2.2.19] +synonym: "H+/K+-ATPase activity" EXACT [EC:7.2.2.19] +synonym: "H+/K+-exchanging ATPase activity" EXACT [EC:7.2.2.19] +synonym: "H,K-ATPase activity" EXACT [EC:7.2.2.19] +synonym: "hydrogen/potassium-exchanging ATPase activity" EXACT [] +synonym: "hydrogen:potassium exchanging ATPase activity" EXACT [] +synonym: "hydrogen:potassium-exchanging ATPase activity" EXACT [] +synonym: "proton pump activity" BROAD [EC:3.6.3.10] +xref: EC:7.2.2.19 +xref: Reactome:R-HSA-937311 "ATP4A/12A:ATP4B exchanges K+ for H+" +xref: RHEA:22044 +is_a: GO:0008553 ! proton-exporting ATPase activity, phosphorylative mechanism +is_a: GO:0008556 ! potassium transmembrane transporter activity, phosphorylative mechanism + +[Term] +id: GO:0008901 +name: ferredoxin hydrogenase activity +namespace: molecular_function +alt_id: GO:0016948 +alt_id: GO:0016949 +alt_id: GO:0016950 +alt_id: GO:0016951 +def: "Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2." [EC:1.12.7.2] +comment: Note that this function was formerly EC:1.12.1.1, EC:1.12.7.1, EC:1.98.1.1, EC:1.18.3.1 and EC:1.18.99.1. +synonym: "[Fe] hydrogenase activity" EXACT [] +synonym: "[Fe] hydrogenase gamma" RELATED [] +synonym: "bidirectional hydrogenase activity" BROAD [EC:1.12.7.2] +synonym: "H(2) oxidizing hydrogenase activity" BROAD [EC:1.12.7.2] +synonym: "H(2) producing hydrogenase activity" BROAD [EC:1.12.7.2] +synonym: "H2 oxidizing hydrogenase" BROAD [] +synonym: "H2 producing hydrogenase" BROAD [] +synonym: "hydrogen-lyase activity" BROAD [EC:1.12.7.2] +synonym: "hydrogen:ferredoxin oxidoreductase activity" EXACT [] +synonym: "hydrogenase (ferredoxin) activity" EXACT [EC:1.12.7.2] +synonym: "hydrogenase activity" BROAD [] +synonym: "hydrogenase I" RELATED [] +synonym: "hydrogenase II" RELATED [] +synonym: "hydrogenlyase activity" BROAD [EC:1.12.7.2] +synonym: "iron hydrogenase activity" NARROW [] +synonym: "iron-only hydrogenase activity" NARROW [] +synonym: "Ni-Fe hydrogenase activity" NARROW [] +synonym: "Ni-Fe-Se hydrogenase activity" NARROW [] +synonym: "nickel hydrogenase activity" NARROW [] +synonym: "nickel-iron hydrogenase activity" NARROW [] +synonym: "nickel-iron-selenium hydrogenase activity" NARROW [] +synonym: "uptake hydrogenase activity" BROAD [EC:1.12.7.2] +xref: EC:1.12.7.2 +xref: MetaCyc:HYDROG-RXN +xref: UM-BBD_enzymeID:e0418 +is_a: GO:0016699 ! oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor + +[Term] +id: GO:0008902 +name: hydroxymethylpyrimidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+)." [EC:2.7.1.49, RHEA:23096] +synonym: "ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity" EXACT [EC:2.7.1.49] +synonym: "hydroxymethylpyrimidine kinase (phosphorylating)" EXACT [EC:2.7.1.49] +xref: EC:2.7.1.49 +xref: KEGG_REACTION:R03471 +xref: MetaCyc:OHMETPYRKIN-RXN +xref: RHEA:23096 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008903 +name: hydroxypyruvate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate." [EC:5.3.1.22, RHEA:11952] +synonym: "hydroxypyruvate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.22] +synonym: "hydroxypyruvate ketol-isomerase activity" EXACT [EC:5.3.1.22] +xref: EC:5.3.1.22 +xref: KEGG_REACTION:R01394 +xref: MetaCyc:RXN0-305 +xref: RHEA:11952 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0008904 +name: hygromycin-B 7''-O-phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+)." [EC:2.7.1.119, RHEA:23388] +synonym: "APH(7'') activity" RELATED [EC:2.7.1.119] +synonym: "ATP:hygromycin-B 7''-O-phosphotransferase activity" EXACT [EC:2.7.1.119] +synonym: "destomic acid ring 7''-O-phosphotransferase activity" EXACT [] +synonym: "hygromycin B kinase activity" BROAD [] +synonym: "hygromycin B phosphotransferase activity" BROAD [EC:2.7.1.119] +synonym: "hygromycin-B kinase activity" BROAD [] +xref: EC:2.7.1.119 +xref: KEGG_REACTION:R03770 +xref: MetaCyc:HYGROMYCIN-B-KINASE-RXN +xref: RHEA:23388 +is_a: GO:0034071 ! aminoglycoside phosphotransferase activity + +[Term] +id: GO:0008905 +name: mannose-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule." [GOC:mah] +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0008906 +name: inosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + inosine = ADP + IMP." [EC:2.7.1.73] +synonym: "ATP:inosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.73] +synonym: "inosine kinase (phosphorylating)" EXACT [EC:2.7.1.73] +synonym: "inosine-guanosine kinase activity" RELATED [EC:2.7.1.73] +xref: EC:2.7.1.73 +xref: MetaCyc:INOSINEKIN-RXN +xref: RHEA:21140 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008907 +name: integrase activity +namespace: molecular_function +def: "Catalysis of the integration of one segment of DNA into another." [GOC:mah] +subset: goslim_pir +xref: Reactome:R-HSA-164523 "Transesterification to connect viral DNA 3' ends to host DNA 5' ends" +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0015074 ! DNA integration + +[Term] +id: GO:0008908 +name: isochorismatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate." [EC:3.3.2.1, RHEA:11112] +synonym: "2,3 dihydro-2,3 dihydroxybenzoate synthase activity" EXACT [EC:3.3.2.1] +synonym: "2,3-dihydro-2,3-dihydroxybenzoate synthase activity" EXACT [EC:3.3.2.1] +synonym: "2,3-dihydroxy-2,3-dihydrobenzoate synthase activity" EXACT [EC:3.3.2.1] +synonym: "2,3-dihydroxy-2,3-dihydrobenzoic synthase activity" EXACT [EC:3.3.2.1] +synonym: "isochorismate pyruvate-hydrolase activity" EXACT [EC:3.3.2.1] +xref: EC:3.3.2.1 +xref: KEGG_REACTION:R03037 +xref: MetaCyc:ISOCHORMAT-RXN +xref: RHEA:11112 +is_a: GO:0004463 ! leukotriene-A4 hydrolase activity + +[Term] +id: GO:0008909 +name: isochorismate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: chorismate = isochorismate." [EC:5.4.4.2, RHEA:18985] +comment: Note that this function was formerly EC:5.4.99.6. +synonym: "isochorismate hydroxymutase activity" EXACT [EC:5.4.4.2] +synonym: "isochorismate mutase activity" EXACT [] +synonym: "isochorismate synthetase activity" EXACT [EC:5.4.4.2] +xref: EC:5.4.4.2 +xref: KEGG_REACTION:R01717 +xref: MetaCyc:ISOCHORSYN-RXN +xref: RHEA:18985 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0008910 +name: kanamycin kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate." [EC:2.7.1.95, RHEA:24256] +synonym: "aminoglycoside 3'-phosphotransferase activity" EXACT [EC:2.7.1.95] +synonym: "APH(3') activity" EXACT [EC:2.7.1.95] +synonym: "ATP:kanamycin 3'-O-phosphotransferase activity" EXACT [EC:2.7.1.95] +synonym: "kanamycin kinase (phosphorylating)" EXACT [EC:2.7.1.95] +synonym: "neomycin phosphotransferase activity" EXACT [EC:2.7.1.95] +synonym: "neomycin-kanamycin phosphotransferase activity" EXACT [EC:2.7.1.95] +xref: EC:2.7.1.95 +xref: KEGG_REACTION:R01888 +xref: MetaCyc:KANAMYCIN-KINASE-RXN +xref: RHEA:24256 +is_a: GO:0034071 ! aminoglycoside phosphotransferase activity + +[Term] +id: GO:0008911 +name: lactaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+." [EC:1.2.1.22] +synonym: "(S)-lactaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.22] +synonym: "L-lactaldehyde:NAD oxidoreductase activity" EXACT [EC:1.2.1.22] +synonym: "nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity" EXACT [EC:1.2.1.22] +xref: EC:1.2.1.22 +xref: MetaCyc:LACTALDDEHYDROG-RXN +xref: RHEA:14277 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0008912 +name: lactaldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+." [EC:1.1.1.77] +synonym: "(R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.77] +synonym: "lactaldehyde:propanediol oxidoreductase activity" EXACT [EC:1.1.1.77] +synonym: "propanediol oxidoreductase activity" BROAD [EC:1.1.1.77] +synonym: "propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity" EXACT [EC:1.1.1.77] +xref: EC:1.1.1.77 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008913 +name: lauroyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another." [GOC:jl, ISBN:0198506732] +synonym: "lauroyl transferase activity" EXACT [] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0008914 +name: leucyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein." [EC:2.3.2.6] +synonym: "L-leucyl-tRNA:protein leucyltransferase activity" EXACT [EC:2.3.2.6] +synonym: "L/F transferase activity" EXACT [EC:2.3.2.6] +synonym: "leucyl, phenylalanine-tRNA-protein transferase activity" EXACT [EC:2.3.2.6] +synonym: "leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity" EXACT [EC:2.3.2.6] +synonym: "leucyl-phenylalanine-transfer ribonucleate-protein transferase activity" EXACT [EC:2.3.2.6] +synonym: "leucyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.6] +synonym: "leucyl/phenylalanyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.6] +xref: EC:2.3.2.6 +xref: MetaCyc:LEUCYLTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0008915 +name: lipid-A-disaccharide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP." [EC:2.4.1.182, RHEA:22668] +synonym: "UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity" EXACT [EC:2.4.1.182] +xref: EC:2.4.1.182 +xref: KEGG_REACTION:R04606 +xref: MetaCyc:LIPIDADISACCHARIDESYNTH-RXN +xref: RHEA:22668 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008917 +name: lipopolysaccharide N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide." [EC:2.4.1.56, GOC:mr, KEGG:00540] +synonym: "LPS N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.56] +synonym: "UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.56] +synonym: "uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.56] +xref: EC:2.4.1.56 +xref: MetaCyc:2.4.1.56-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0008918 +name: lipopolysaccharide 3-alpha-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide." [EC:2.4.1.44, GOC:mr, KEGG:00540] +synonym: "lipopolysaccharide 1,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "lipopolysaccharide galactosyltransferase activity" EXACT [] +synonym: "lipopolysaccharide-alpha-1,3-D-galactosyltransferase" NARROW [] +synonym: "LPS 3-alpha-galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "UDP-galactose:polysaccharide galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity" EXACT [EC:2.4.1.44] +synonym: "uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] +xref: EC:2.4.1.44 +xref: MetaCyc:2.4.1.44-RXN +is_a: GO:0035250 ! UDP-galactosyltransferase activity +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0008919 +name: lipopolysaccharide glucosyltransferase I activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide." [EC:2.4.1.58, GOC:mr, KEGG:00540] +synonym: "lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] +synonym: "LPS glucosyltransferase I activity" EXACT [] +synonym: "UDP-glucose:lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] +synonym: "UDPglucose:lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] +synonym: "UDPglucose:lipopolysaccharide glucosyltransferase I" RELATED [EC:2.4.1.58] +synonym: "uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I" RELATED [EC:2.4.1.58] +synonym: "uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] +xref: EC:2.4.1.58 +xref: MetaCyc:2.4.1.58-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0008920 +name: lipopolysaccharide heptosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+." [MetaCyc:RXN0-5061, MetaCyc:RXN0-5122, MetaCyc:RXN0-5127] +synonym: "LPS heptosyltransferase activity" EXACT [] +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups + +[Term] +id: GO:0008921 +name: lipopolysaccharide-1,6-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide." [GOC:ai] +synonym: "LPS-1,6-galactosyltransferase activity" EXACT [] +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0008922 +name: long-chain fatty acid [acyl-carrier-protein] ligase activity +namespace: molecular_function +alt_id: GO:0010300 +def: "Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22." [EC:6.2.1.20] +synonym: "acyl-[acyl-carrier-protein] synthetase activity" EXACT [EC:6.2.1.20] +synonym: "acyl-ACP synthetase activity" EXACT [] +synonym: "acyl-acyl carrier protein synthetase" BROAD [EC:6.2.1.20] +synonym: "acyl-acyl-carrier-protein synthetase activity" EXACT [EC:6.2.1.20] +synonym: "acyl-acyl-carrier-proteinsynthetase activity" EXACT [EC:6.2.1.20] +synonym: "long-chain fatty acid-[acyl-carrier-protein] ligase activity" EXACT [] +synonym: "long-chain-fatty-acid-[acyl-carrier protein] ligase activity" EXACT [] +synonym: "long-chain-fatty-acid-[acyl-carrier-protein] ligase activity" EXACT [] +synonym: "long-chain-fatty-acid-ACP ligase activity" EXACT [] +synonym: "long-chain-fatty-acid-acyl-carrier-protein ligase activity" EXACT [EC:6.2.1.20] +synonym: "long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity" EXACT [EC:6.2.1.20] +synonym: "stearoyl-ACP synthetase activity" EXACT [EC:6.2.1.20] +xref: EC:6.2.1.20 +xref: KEGG_REACTION:R07325 +xref: MetaCyc:ACYLACPSYNTH-RXN +is_a: GO:0015645 ! fatty acid ligase activity + +[Term] +id: GO:0008923 +name: lysine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2)." [EC:4.1.1.18, RHEA:22352] +synonym: "L-lysine carboxy-lyase (cadaverine-forming)" EXACT [EC:4.1.1.18] +synonym: "L-lysine carboxy-lyase activity" EXACT [EC:4.1.1.18] +xref: EC:4.1.1.18 +xref: KEGG_REACTION:R00462 +xref: MetaCyc:LYSDECARBOX-RXN +xref: MetaCyc:PWY0-461 +xref: RHEA:22352 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008924 +name: malate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol." [MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN] +synonym: "(S)-malate:(quinone) oxidoreductase activity" EXACT [EC:1.1.5.4] +synonym: "(S)-malate:quinone oxidoreductase activity" EXACT [EC:1.1.5.4] +synonym: "FAD-dependent malate dehydrogenase activity" EXACT [EC:1.1.5.4] +synonym: "MQO activity" BROAD [EC:1.1.5.4] +xref: EC:1.1.5.4 +xref: MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN +xref: RHEA:22556 +is_a: GO:0016615 ! malate dehydrogenase activity +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0008925 +name: maltose O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose." [EC:2.3.1.79] +synonym: "acetyl-CoA:maltose O-acetyltransferase activity" EXACT [EC:2.3.1.79] +synonym: "maltose transacetylase activity" EXACT [EC:2.3.1.79] +xref: EC:2.3.1.79 +xref: MetaCyc:MALTACETYLTRAN-RXN +xref: RHEA:10456 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0008926 +name: mannitol-1-phosphate 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.17] +xref: EC:1.1.1.17 +xref: MetaCyc:MANNPDEHYDROG-RXN +xref: RHEA:19661 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008927 +name: mannonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O." [EC:4.2.1.8, RHEA:20097] +synonym: "altronate hydrolase activity" EXACT [EC:4.2.1.8] +synonym: "altronic hydro-lyase activity" EXACT [EC:4.2.1.8] +synonym: "D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.2.1.8] +synonym: "D-mannonate hydro-lyase activity" EXACT [EC:4.2.1.8] +synonym: "D-mannonate hydrolyase activity" EXACT [EC:4.2.1.8] +synonym: "mannonate hydrolyase activity" EXACT [EC:4.2.1.8] +synonym: "mannonic hydrolase activity" EXACT [EC:4.2.1.8] +xref: EC:4.2.1.8 +xref: KEGG_REACTION:R05606 +xref: MetaCyc:MANNONDEHYDRAT-RXN +xref: RHEA:20097 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0008928 +name: mannose-1-phosphate guanylyltransferase (GDP) activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate." [EC:2.7.7.22, RHEA:12905] +synonym: "GDP mannose phosphorylase activity" EXACT [EC:2.7.7.22] +synonym: "GDP-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] +synonym: "GDP-mannose phosphorylase activity" EXACT [EC:2.7.7.22] +synonym: "GDP-mannose pyrophosphorylase activity" RELATED [EC:2.7.7.22] +synonym: "GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] +synonym: "GDP:D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] +synonym: "GDP:mannose-1-phosphate guanylyltransferase activity" EXACT [] +synonym: "guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] +synonym: "guanosine diphosphomannose phosphorylase activity" EXACT [EC:2.7.7.22] +synonym: "mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity" EXACT [EC:2.7.7.22] +synonym: "mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] +xref: EC:2.7.7.22 +xref: KEGG_REACTION:R00883 +xref: MetaCyc:MANNPGUANYLTRANGDP-RXN +xref: RHEA:12905 +is_a: GO:0008905 ! mannose-phosphate guanylyltransferase activity + +[Term] +id: GO:0008929 +name: methylglyoxal synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate." [EC:4.2.3.3, RHEA:17937] +synonym: "glycerone-phosphate phospho-lyase (methylglyoxal-forming)" EXACT [EC:4.2.3.3] +synonym: "glycerone-phosphate phospho-lyase activity" EXACT [EC:4.2.3.3] +synonym: "methylglyoxal synthetase activity" EXACT [EC:4.2.3.3] +xref: EC:4.2.3.3 +xref: KEGG_REACTION:R01016 +xref: MetaCyc:METHGLYSYN-RXN +xref: RHEA:17937 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0008930 +name: methylthioadenosine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose." [EC:3.2.2.16] +synonym: "5'-methylthioadenosine nucleosidase activity" EXACT [EC:3.2.2.16] +synonym: "MeSAdo nucleosidase activity" EXACT [EC:3.2.2.16] +synonym: "methylthioadenosine methylthioribohydrolase activity" EXACT [EC:3.2.2.16] +synonym: "MTA nucleosidase activity" EXACT [EC:3.2.2.16] +synonym: "S-methyl-5'-thioadenosine adeninehyrolase activity" EXACT [EC:3.2.2.16] +xref: EC:3.2.2.16 +xref: MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN +xref: RHEA:13617 +is_a: GO:0008477 ! purine nucleosidase activity + +[Term] +id: GO:0008931 +name: obsolete murein DD-endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "murein DD-endopeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008932 +name: lytic endotransglycosylase activity +namespace: molecular_function +def: "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends." [PMID:10964424, PMID:9642199] +synonym: "murein lytic endotransglycosylase E activity" NARROW [] +xref: EC:2.4.99 +is_a: GO:0008933 ! lytic transglycosylase activity + +[Term] +id: GO:0008933 +name: lytic transglycosylase activity +namespace: molecular_function +def: "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues." [PMID:10964424, PMID:22748813] +synonym: "murein transglycosylase B activity" NARROW [] +synonym: "peptidoglycan lytic transglycosylase activity" EXACT [] +xref: EC:3.2.1 +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups +is_a: GO:0061783 ! peptidoglycan muralytic activity + +[Term] +id: GO:0008934 +name: inositol monophosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25] +synonym: "inositol 1-phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "inositol-1(or 4)-monophosphatase activity" BROAD [EC:3.1.3.25] +synonym: "L-myo-inositol-1-phosphate phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol 1-phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol-1(or 4)-monophosphatase activity" BROAD [] +synonym: "myo-inositol-1(or 4)-phosphate phosphohydrolase activity" BROAD [EC:3.1.3.25] +synonym: "myo-inositol-1-phosphatase activity" EXACT [EC:3.1.3.25] +xref: EC:3.1.3.25 +xref: MetaCyc:RXN0-5408 +xref: Reactome:R-HSA-1855154 "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol" +xref: RHEA:27670 +is_a: GO:0052834 ! inositol monophosphate phosphatase activity + +[Term] +id: GO:0008935 +name: 1,4-dihydroxy-2-naphthoyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O." [EC:4.1.3.36] +synonym: "1,4-dihydroxy-2-naphthoate synthase activity" EXACT [EC:4.1.3.36] +synonym: "DHNA synthetase activity" EXACT [EC:4.1.3.36] +synonym: "dihydroxynaphthoate synthase activity" EXACT [EC:4.1.3.36] +synonym: "dihydroxynaphthoic acid synthetase activity" EXACT [EC:4.1.3.36] +synonym: "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity" EXACT [EC:4.1.3.36] +synonym: "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing; CoA-forming)" EXACT [EC:4.1.3.36] +synonym: "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase activity" RELATED [KEGG_REACTION:R04150] +xref: EC:4.1.3.36 +xref: KEGG_REACTION:R04150 +xref: MetaCyc:NAPHTHOATE-SYN-RXN +xref: RHEA:15525 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0008936 +name: nicotinamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3." [EC:3.5.1.19] +synonym: "NAMase activity" EXACT [EC:3.5.1.19] +synonym: "nicotinamide amidase activity" EXACT [EC:3.5.1.19] +synonym: "nicotinamide amidohydrolase activity" EXACT [EC:3.5.1.19] +synonym: "nicotinamide deaminase activity" EXACT [EC:3.5.1.19] +synonym: "nicotine deamidase activity" EXACT [EC:3.5.1.19] +synonym: "YNDase activity" EXACT [EC:3.5.1.19] +xref: EC:3.5.1.19 +xref: MetaCyc:NICOTINAMID-RXN +xref: RHEA:14545 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008937 +name: ferredoxin-NAD(P) reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+." [EC:1.18.1.-] +synonym: "ferredoxin reductase activity" BROAD [] +xref: EC:1.18.1 +is_a: GO:0016731 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor + +[Term] +id: GO:0008938 +name: nicotinate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine." [EC:2.1.1.7, RHEA:20241] +synonym: "furanocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.7] +synonym: "S-adenosyl-L-methionine:nicotinate N-methyltransferase activity" EXACT [EC:2.1.1.7] +xref: EC:2.1.1.7 +xref: KEGG_REACTION:R01721 +xref: MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN +xref: RHEA:20241 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0008939 +name: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate." [EC:2.4.2.21, RHEA:11196] +synonym: "CobT" RELATED [EC:2.4.2.21] +synonym: "N(1)-alpha-phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "N1-alpha-phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.21] +synonym: "nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.21] +xref: EC:2.4.2.21 +xref: KEGG_REACTION:R04148 +xref: MetaCyc:DMBPPRIBOSYLTRANS-RXN +xref: RHEA:11196 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0008940 +name: nitrate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor." [EC:1.7.99.4] +synonym: "nitrate reductase (acceptor)" EXACT [EC:1.7.99.4] +synonym: "nitrite:(acceptor) oxidoreductase" EXACT [EC:1.7.99.4] +synonym: "nitrite:acceptor oxidoreductase" EXACT [EC:1.7.99.4] +synonym: "respiratory nitrate reductase activity" NARROW [EC:1.7.99.4] +xref: EC:1.7.99.4 +xref: MetaCyc:NITRATREDUCT-RXN +xref: RHEA:21068 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0008941 +name: nitric oxide dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+." [EC:1.14.12.17] +synonym: "nitric oxide,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.12.17] +synonym: "NOD activity" EXACT [EC:1.14.12.17] +xref: EC:1.14.12.17 +xref: MetaCyc:R621-RXN +xref: Reactome:R-HSA-1222723 "Nitric oxide is oxidized to nitrate" +xref: Reactome:R-HSA-5340226 "CYGB dioxygenates NO" +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0008942 +name: nitrite reductase [NAD(P)H] activity +namespace: molecular_function +def: "Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+." [EC:1.7.1.4] +comment: Note that this function was formerly EC:1.6.6.4. +synonym: "ammonium-hydroxide:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.4] +synonym: "assimilatory nitrite reductase activity" RELATED [EC:1.7.1.4] +synonym: "NAD(P)H2:nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] +synonym: "NAD(P)H:nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] +synonym: "NADH-nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] +synonym: "NADPH-nitrite reductase activity" EXACT [EC:1.7.1.4] +synonym: "nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.7.1.4] +synonym: "nitrite reductase [NAD(P)H2]" RELATED [EC:1.7.1.4] +xref: EC:1.7.1.4 +xref: KEGG_REACTION:R00787 +xref: KEGG_REACTION:R00789 +xref: MetaCyc:NITRITREDUCT-RXN +xref: RHEA:24628 +xref: RHEA:24632 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor +is_a: GO:0098809 ! nitrite reductase activity + +[Term] +id: GO:0008943 +name: obsolete glyceraldehyde-3-phosphate dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+." [EC:1.2.1.12, EC:1.2.1.13, EC:1.2.1.9] +comment: This term was made obsolete because it is a grouping term based on similar names. +synonym: "glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] +is_obsolete: true +consider: GO:0004365 +consider: GO:0008886 +consider: GO:0043878 +consider: GO:0047100 + +[Term] +id: GO:0008944 +name: obsolete oligopeptidase A activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5." [EC:3.4.24.70] +comment: This term was made obsolete because it represents a gene product. +synonym: "68000-M signalpeptide hydrolase activity" EXACT [EC:3.4.24.70] +synonym: "oligopeptidase A activity" EXACT [] +xref: EC:3.4.24.70 +xref: MetaCyc:3.4.24.70-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008945 +name: obsolete oligopeptidase B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline." [EC:3.4.21.83] +comment: This term was made obsolete because it represents a gene product. +synonym: "Escherichia coli alkaline proteinase II" RELATED [EC:3.4.21.83] +synonym: "oligopeptidase B activity" EXACT [] +synonym: "protease II activity" EXACT [EC:3.4.21.83] +xref: EC:3.4.21.83 +xref: MetaCyc:3.4.21.83-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008946 +name: oligonucleotidase activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates." [EC:3.1.13.3] +comment: Note that enzymes with this activity usually also hydrolyze NAD+ to NMN and AMP. +xref: EC:3.1.13.3 +xref: MetaCyc:3.1.13.3-RXN +is_a: GO:0004518 ! nuclease activity + +[Term] +id: GO:0008947 +name: obsolete omptin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys." [EC:3.4.21.87] +comment: This term was made obsolete because it represents a gene product. +synonym: "omptin activity" EXACT [] +xref: EC:3.4.21.87 +xref: MetaCyc:3.4.21.87-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008948 +name: oxaloacetate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxaloacetate = pyruvate + CO2." [EC:1.1.1.38, EC:1.1.1.40, EC:4.1.1.112] +synonym: "oxalacetic acid decarboxylase activity" EXACT [] +synonym: "oxalate beta-decarboxylase activity" EXACT [EC:4.1.1.112] +synonym: "oxaloacetate beta-decarboxylase activity" EXACT [EC:4.1.1.112] +synonym: "oxaloacetate carboxy-lyase (pyruvate-forming)" EXACT [] +synonym: "oxaloacetate carboxy-lyase activity" EXACT [EC:4.1.1.112] +xref: EC:1.1.1.38 +xref: EC:1.1.1.40 +xref: EC:4.1.1.112 +xref: KEGG_REACTION:R00217 +xref: MetaCyc:OXALODECARB-RXN +xref: Reactome:R-HSA-9012016 "FAHD1:Zn2+ dimer hydrolyses OA to PYR" +xref: RHEA:15641 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008949 +name: oxalyl-CoA decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA." [EC:4.1.1.8, RHEA:19333] +synonym: "oxalyl coenzyme A decarboxylase activity" EXACT [EC:4.1.1.8] +synonym: "oxalyl-CoA carboxy-lyase (formyl-CoA-forming)" EXACT [EC:4.1.1.8] +synonym: "oxalyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.8] +xref: EC:4.1.1.8 +xref: KEGG_REACTION:R01908 +xref: MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN +xref: RHEA:19333 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0008950 +name: obsolete p-aminobenzoate synthetase +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:krc] +comment: This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered. +synonym: "p-aminobenzoate synthetase" EXACT [] +is_obsolete: true +consider: GO:0008696 +consider: GO:0046820 + +[Term] +id: GO:0008951 +name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein]." [MetaCyc:PALMITOTRANS-RXN] +synonym: "palmitoleoyl ACP-dependent acyltransferase activity" EXACT [] +xref: MetaCyc:PALMITOTRANS-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0008953 +name: penicillin amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate." [EC:3.5.1.11] +synonym: "alpha-acylamino-beta-lactam acylhydrolase activity" EXACT [EC:3.5.1.11] +synonym: "ampicillin acylase activity" EXACT [EC:3.5.1.11] +synonym: "benzylpenicillin acylase activity" EXACT [EC:3.5.1.11] +synonym: "novozym 217" RELATED [EC:3.5.1.11] +synonym: "palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity" EXACT [] +synonym: "penicillin acylase activity" EXACT [EC:3.5.1.11] +synonym: "penicillin amidohydrolase activity" EXACT [EC:3.5.1.11] +synonym: "semacylase activity" EXACT [EC:3.5.1.11] +xref: EC:3.5.1.11 +xref: MetaCyc:PENICILLIN-AMIDASE-RXN +xref: RHEA:18693 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0008954 +name: obsolete peptidoglycan synthetase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it was not defined, is ambiguous, and has been used to annotate gene products with very different activities. +synonym: "peptidoglycan synthetase activity" EXACT [] +is_obsolete: true +consider: GO:0008955 +consider: GO:0071972 + +[Term] +id: GO:0008955 +name: peptidoglycan glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate." [EC:2.4.1.129] +synonym: "bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.129] +synonym: "penicillin binding protein (3 or 1B) activity" NARROW [EC:2.4.1.129] +synonym: "peptidoglycan TGase activity" EXACT [EC:2.4.1.129] +synonym: "peptidoglycan transglycosylase activity" EXACT [EC:2.4.1.129] +synonym: "PG-II activity" EXACT [EC:2.4.1.129] +synonym: "undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity" EXACT [EC:2.4.1.129] +xref: EC:2.4.1.129 +xref: MetaCyc:RXN0-5405 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0008956 +name: obsolete peptidyl-dipeptidase Dcp activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly." [EC:3.4.15.5] +comment: This term was made obsolete because it represents a gene product. +synonym: "dipeptidyl carboxypeptidase (Dcp)" EXACT [EC:3.4.15.5] +synonym: "dipeptidyl carboxypeptidase activity" EXACT [EC:3.4.15.5] +synonym: "peptidyl-dipeptidase Dcp activity" EXACT [] +xref: EC:3.4.15.5 +xref: MetaCyc:3.4.15.5-RXN +is_obsolete: true +consider: GO:0008235 +consider: GO:0008241 + +[Term] +id: GO:0008957 +name: phenylacetaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+." [EC:1.2.1.39] +synonym: "phenylacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.39] +xref: EC:1.2.1.39 +xref: MetaCyc:PHENDEHYD-RXN +xref: RHEA:21392 +xref: UM-BBD_reactionID:r0035 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0008959 +name: phosphate acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate." [EC:2.3.1.8] +synonym: "acetyl-CoA:phosphate acetyltransferase activity" EXACT [EC:2.3.1.8] +synonym: "phosphoacylase activity" EXACT [EC:2.3.1.8] +synonym: "phosphotransacetylase activity" EXACT [EC:2.3.1.8] +synonym: "PTA" RELATED [EC:2.3.1.8] +xref: EC:2.3.1.8 +xref: MetaCyc:PHOSACETYLTRANS-RXN +xref: RHEA:19521 +is_a: GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0008960 +name: phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose." [EC:2.7.8.20] +synonym: "oligosaccharide glycerophosphotransferase activity" EXACT [EC:2.7.8.20] +synonym: "phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity" EXACT [EC:2.7.8.20] +synonym: "phosphoglycerol transferase activity" RELATED [EC:2.7.8.20] +synonym: "phosphoglycerol transferase I" RELATED [EC:2.7.8.20] +xref: EC:2.7.8.20 +xref: MetaCyc:PGLYCEROLTRANSI-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0008961 +name: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein." [PMID:8051048] +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0008962 +name: phosphatidylglycerophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate." [EC:3.1.3.27] +synonym: "PGP phosphatase activity" EXACT [EC:3.1.3.27] +synonym: "phosphatidylglycerol phosphatase activity" EXACT [EC:3.1.3.27] +synonym: "phosphatidylglycerol phosphate phosphatase activity" EXACT [EC:3.1.3.27] +synonym: "phosphatidylglycerophosphate phosphohydrolase activity" EXACT [EC:3.1.3.27] +xref: EC:3.1.3.27 +xref: MetaCyc:PGPPHOSPHA-RXN +xref: Reactome:R-HSA-1483197 "PTPMT1 dephosphorylates PGP to PG" +xref: RHEA:16725 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0008963 +name: phospho-N-acetylmuramoyl-pentapeptide-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol." [EC:2.7.8.13] +comment: Note that EC classifies all three 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under EC:2.7.8.13. +subset: goslim_chembl +synonym: "MraY transferase activity" NARROW [EC:2.7.8.13] +synonym: "phospho-MurNAc-pentapeptide transferase activity" EXACT [EC:2.7.8.13] +synonym: "phospho-N-acetylmuramoyl pentapeptide translocase activity" EXACT [EC:2.7.8.13] +synonym: "phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity" EXACT [EC:2.7.8.13] +synonym: "phosphoacetylmuramoylpentapeptide translocase activity" EXACT [EC:2.7.8.13] +synonym: "phosphoacetylmuramoylpentapeptidetransferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity" EXACT [EC:2.7.8.13] +synonym: "UDP-MurNAc-pentapeptide phosphotransferase activity" EXACT [EC:2.7.8.13] +xref: EC:2.7.8.13 +xref: MetaCyc:RXN-8975 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0008964 +name: phosphoenolpyruvate carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-." [EC:4.1.1.31] +synonym: "PEP carboxylase activity" EXACT [EC:4.1.1.31] +synonym: "PEPC" RELATED [EC:4.1.1.31] +synonym: "PEPCase activity" EXACT [EC:4.1.1.31] +synonym: "phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.31] +synonym: "phosphate:oxaloacetate carboxy-lyase (phosphorylating)" EXACT [EC:4.1.1.31] +synonym: "phosphoenolpyruvic carboxylase activity" EXACT [EC:4.1.1.31] +synonym: "phosphopyruvate (phosphate) carboxylase activity" EXACT [EC:4.1.1.31] +xref: EC:4.1.1.31 +xref: KEGG_REACTION:R00345 +xref: MetaCyc:PEPCARBOX-RXN +xref: RHEA:28370 +is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity + +[Term] +id: GO:0008965 +name: phosphoenolpyruvate-protein phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine." [EC:2.7.3.9] +synonym: "enzyme I of the phosphotransferase system" NARROW [EC:2.7.3.9] +synonym: "phosphoenolpyruvate sugar phosphotransferase enzyme I activity" EXACT [EC:2.7.3.9] +synonym: "phosphoenolpyruvate--protein phosphatase activity" EXACT [EC:2.7.3.9] +synonym: "phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity" EXACT [EC:2.7.3.9] +synonym: "phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity" EXACT [EC:2.7.3.9] +synonym: "phosphopyruvate--protein factor phosphotransferase activity" EXACT [EC:2.7.3.9] +synonym: "phosphopyruvate--protein phosphotransferase activity" EXACT [EC:2.7.3.9] +synonym: "sugar--PEP phosphotransferase enzyme I activity" NARROW [EC:2.7.3.9] +xref: EC:2.7.3.9 +xref: MetaCyc:2.7.3.9-RXN +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0008966 +name: phosphoglucosamine mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate." [EC:5.4.2.10, RHEA:23424] +synonym: "alpha-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.10] +synonym: "D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.10] +xref: EC:5.4.2.10 +xref: KEGG_REACTION:R02060 +xref: MetaCyc:5.4.2.10-RXN +xref: RHEA:23424 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0008967 +name: phosphoglycolate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate." [EC:3.1.3.18, RHEA:14369] +synonym: "2-phosphoglycolate phosphatase activity" EXACT [EC:3.1.3.18] +synonym: "2-phosphoglycolate phosphohydrolase activity" EXACT [EC:3.1.3.18] +synonym: "P-glycolate phosphatase activity" EXACT [EC:3.1.3.18] +synonym: "phosphoglycolate hydrolase activity" EXACT [EC:3.1.3.18] +synonym: "phosphoglycollate phosphatase activity" EXACT [EC:3.1.3.18] +xref: EC:3.1.3.18 +xref: KEGG_REACTION:R01334 +xref: MetaCyc:GPH-RXN +xref: RHEA:14369 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0008968 +name: D-sedoheptulose 7-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate." [MetaCyc:RXN0-4301, PMID:11279237, PMID:8631969] +synonym: "phosphoheptose isomerase activity" EXACT [] +xref: MetaCyc:RXN0-4301 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0008970 +name: phospholipase A1 activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate." [EC:3.1.1.32] +subset: goslim_chembl +synonym: "phosphatidylcholine 1-acylhydrolase activity" EXACT [] +xref: EC:3.1.1.32 +xref: MetaCyc:PHOSPHOLIPASE-A1-RXN +xref: Reactome:R-HSA-1482827 "PC is hydrolyzed to 2-acyl LPC by PLA2G4C" +xref: Reactome:R-HSA-1482828 "PE is hydrolyzed to 2-acyl LPE by PLA2[4]" +xref: Reactome:R-HSA-1482847 "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)" +xref: Reactome:R-HSA-1482862 "PC is hydrolysed to 2-acyl LPC by PLA2[7]" +xref: Reactome:R-HSA-1482892 "PE is hydrolyzed to 2-acyl LPE by PLA2G4C" +xref: Reactome:R-HSA-1482920 "PG is hydrolyzed to 2-acyl LPG by PLA2[14]" +xref: Reactome:R-HSA-1482932 "PI is hydrolyzed to 2-acyl LPI by PLA2[13]" +xref: Reactome:R-HSA-5694485 "ABHD3 hydrolyses LPC(14:0) to 1AGPC" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0008972 +name: phosphomethylpyrimidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine." [EC:2.7.4.7] +synonym: "ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity" EXACT [EC:2.7.4.7] +synonym: "hydroxymethylpyrimidine phosphokinase activity" EXACT [EC:2.7.4.7] +xref: EC:2.7.4.7 +xref: MetaCyc:PYRIMSYN3-RXN +xref: RHEA:19893 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0008973 +name: phosphopentomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate." [EC:5.4.2.7] +synonym: "alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity" EXACT [EC:5.4.2.7] +synonym: "alpha-D-ribose 1,5-phosphomutase activity" EXACT [EC:5.4.2.7] +synonym: "D-ribose 1,5-phosphomutase activity" EXACT [EC:5.4.2.7] +synonym: "deoxyribomutase activity" RELATED [EC:5.4.2.7] +synonym: "deoxyribose phosphomutase activity" RELATED [EC:5.4.2.7] +synonym: "phosphodeoxyribomutase activity" RELATED [EC:5.4.2.7] +synonym: "phosphoribomutase activity" EXACT [EC:5.4.2.7] +xref: EC:5.4.2.7 +xref: MetaCyc:PPENTOMUT-RXN +xref: Reactome:R-HSA-6787329 "PGM2:Mg2+ isomerises R1P to R5P" +xref: Reactome:R-HSA-8982667 "PGM2:Mg2+ isomerises dR1P to dR5P" +xref: RHEA:18793 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0008974 +name: phosphoribulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.19, RHEA:19365] +synonym: "5-phosphoribulose kinase activity" EXACT [EC:2.7.1.19] +synonym: "ATP:D-ribulose-5-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.19] +synonym: "phosphopentokinase activity" RELATED [EC:2.7.1.19] +synonym: "phosphoribulokinase (phosphorylating)" EXACT [EC:2.7.1.19] +synonym: "PKK" RELATED [EC:2.7.1.19] +synonym: "PRK" RELATED [EC:2.7.1.19] +synonym: "PRuK" RELATED [EC:2.7.1.19] +synonym: "ribulose phosphate kinase activity" EXACT [EC:2.7.1.19] +synonym: "ribulose-5-phosphate kinase activity" EXACT [EC:2.7.1.19] +xref: EC:2.7.1.19 +xref: KEGG_REACTION:R01523 +xref: MetaCyc:PHOSPHORIBULOKINASE-RXN +xref: RHEA:19365 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0008975 +name: obsolete pitrilysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon." [EC:3.4.24.55] +comment: This term was made obsolete because it represents a gene product. +synonym: "Escherichia coli metalloproteinase Pi" RELATED [EC:3.4.24.55] +synonym: "Escherichia coli protease III" RELATED [EC:3.4.24.55] +synonym: "pitrilysin activity" EXACT [] +synonym: "protease III activity" EXACT [EC:3.4.24.55] +synonym: "protease Pi activity" EXACT [EC:3.4.24.55] +synonym: "proteinase Pi" RELATED [EC:3.4.24.55] +synonym: "PTR" RELATED [EC:3.4.24.55] +xref: EC:3.4.24.55 +xref: MetaCyc:3.4.24.55-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0008976 +name: polyphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1)." [EC:2.7.4.1] +synonym: "ATP-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.1] +synonym: "ATP:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.1] +synonym: "polyphosphate polymerase activity" EXACT [] +synonym: "polyphosphoric acid kinase activity" EXACT [EC:2.7.4.1] +xref: EC:2.7.4.1 +xref: MetaCyc:POLYPHOSPHATE-KINASE-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0008977 +name: prephenate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH." [EC:1.3.1.12, RHEA:13869] +synonym: "chorismate mutase--prephenate dehydrogenase activity" EXACT [EC:1.3.1.12] +synonym: "hydroxyphenylpyruvate synthase activity" BROAD [EC:1.3.1.12] +synonym: "prephenate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.12] +xref: EC:1.3.1.12 +xref: KEGG_REACTION:R01728 +xref: MetaCyc:PREPHENATEDEHYDROG-RXN +xref: RHEA:13869 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0008978 +name: obsolete prepilin peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine." [EC:3.4.23.43] +comment: This term was made obsolete because it represents a gene product. +synonym: "prepilin peptidase activity" EXACT [] +xref: EC:3.4.23.43 +xref: MetaCyc:3.4.23.43-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0008979 +name: prophage integrase activity +namespace: molecular_function +def: "Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA." [GOC:jl] +synonym: "integrase activity involved in establishment of integrated proviral latency" EXACT [] +is_a: GO:0008907 ! integrase activity +is_a: GO:0009009 ! site-specific recombinase activity +relationship: part_of GO:0075713 ! establishment of integrated proviral latency + +[Term] +id: GO:0008980 +name: propionate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate." [EC:2.7.2.15] +synonym: "ATP:propanoate phosphotransferase activity" EXACT [] +synonym: "PduW" RELATED [] +synonym: "propanoate kinase activity" EXACT [] +synonym: "TdcD" RELATED [] +xref: EC:2.7.2.15 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0008981 +name: obsolete protease IV activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "protease IV activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008982 +name: protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +namespace: molecular_function +alt_id: GO:0015455 +alt_id: GO:0015456 +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [EC:2.7.1.69, GOC:mtg_transport, http://www.ucs.mun.ca/~n55lrb/general_pts.html, ISBN:0815340729, TC:4.A.-.-.-] +synonym: "enzyme II of the phosphotransferase system" NARROW [EC:2.7.1.69] +synonym: "enzyme IIl4ac" RELATED [EC:2.7.1.69] +synonym: "gene bglC RNA formation factors" RELATED [EC:2.7.1.69] +synonym: "gene glC proteins" RELATED [EC:2.7.1.69] +synonym: "group translocator activity" RELATED [EC:2.7.1.69] +synonym: "PEP--sugar phosphotransferase enzyme II activity" NARROW [EC:2.7.1.69] +synonym: "PEP-dependent phosphotransferase enzyme II" RELATED [EC:2.7.1.69] +synonym: "phosphoenolpyruvate-sugar phosphotransferase enzyme II" RELATED [EC:2.7.1.69] +synonym: "phosphohistidinoprotein-hexose phosphoribosyltransferase activity" EXACT [EC:2.7.1.69] +synonym: "phosphohistidinoprotein-hexose phosphotransferase activity" EXACT [EC:2.7.1.69] +synonym: "phosphoprotein factor-hexose phosophotransferase activity" EXACT [EC:2.7.1.69] +synonym: "phosphotransfer-driven group translocator" EXACT [] +synonym: "phosphotransferase, phosphohistidinoprotein-hexose activity" EXACT [EC:2.7.1.69] +synonym: "protein, specific or class, gene bglC" RELATED [EC:2.7.1.69] +synonym: "protein-Np-phosphohistidine-sugar phosphotransferase activity" EXACT [] +synonym: "protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity" EXACT [EC:2.7.1.69] +synonym: "protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity" EXACT [EC:2.7.1.69] +synonym: "protein-Npi-phosphohistidine-sugar phosphotransferase activity" EXACT [EC:2.7.1.69] +synonym: "protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity" EXACT [EC:2.7.1.69] +synonym: "PTS permease activity" EXACT [EC:2.7.1.69] +synonym: "PTS transporter" RELATED [EC:2.7.1.69] +synonym: "ribonucleic acid formation factor, gene glC" RELATED [EC:2.7.1.69] +synonym: "sucrose phosphotransferase system II" RELATED [EC:2.7.1.69] +xref: EC:2.7.1.69 +xref: MetaCyc:2.7.1.69-RXN +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0022804 ! active transmembrane transporter activity + +[Term] +id: GO:0008983 +name: protein-glutamate O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester." [EC:2.1.1.80, RESID:AA0072] +synonym: "MCP methyltransferase I" RELATED [EC:2.1.1.80] +synonym: "MCP methyltransferase II" RELATED [EC:2.1.1.80] +synonym: "methyl-accepting chemotaxis protein methyltransferase II" RELATED [EC:2.1.1.80] +synonym: "methyl-accepting chemotaxis protein O-methyltransferase activity" NARROW [EC:2.1.1.80] +synonym: "protein carboxyl-methylase activity" EXACT [EC:2.1.1.80] +synonym: "protein carboxyl-O-methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "protein carboxylmethyltransferase II" RELATED [EC:2.1.1.80] +synonym: "protein carboxymethylase activity" EXACT [EC:2.1.1.80] +synonym: "protein carboxymethyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "protein methylase II" RELATED [EC:2.1.1.80] +synonym: "protein O-methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "protein(aspartate)methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "protein(carboxyl)methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "S-adenosylmethionine-glutamyl methyltransferase activity" EXACT [EC:2.1.1.80] +synonym: "S-adenosylmethionine:protein-carboxyl O-methyltransferase activity" EXACT [EC:2.1.1.80] +xref: EC:2.1.1.80 +xref: MetaCyc:CHER-RXN +xref: RESID:AA0072 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0051998 ! protein carboxyl O-methyltransferase activity + +[Term] +id: GO:0008984 +name: protein-glutamate methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol." [EC:3.1.1.61, RESID:AA0072] +synonym: "CheB methylesterase activity" NARROW [EC:3.1.1.61] +synonym: "chemotaxis-specific methylesterase activity" NARROW [EC:3.1.1.61] +synonym: "methyl-accepting chemotaxis protein methyl-esterase activity" NARROW [EC:3.1.1.61] +synonym: "methylesterase CheB activity" NARROW [EC:3.1.1.61] +synonym: "protein-L-glutamate-5-O-methyl-ester acylhydrolase activity" EXACT [EC:3.1.1.61] +synonym: "protein-L-glutamate-O5-methyl-ester acylhydrolase activity" EXACT [EC:3.1.1.61] +xref: EC:3.1.1.61 +xref: MetaCyc:MCPMETEST-RXN +xref: RESID:AA0072 +is_a: GO:0051723 ! protein methylesterase activity + +[Term] +id: GO:0008985 +name: obsolete pyruvate dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1." [EC:1.2.2.2] +comment: This term was made obsolete because the EC activity it represents, EC:1.2.2.2, has been deleted. +synonym: "pyruvate dehydrogenase (cytochrome) activity" EXACT [] +synonym: "pyruvate:ferricytochrome-b1 oxidoreductase activity" RELATED [EC:1.2.2.2] +synonym: "pyruvate:ubiquinone-8-oxidoreductase activity" RELATED [EC:1.2.2.2] +synonym: "pyruvic (cytochrome b1) dehydrogenase activity" RELATED [EC:1.2.2.2] +is_obsolete: true +replaced_by: GO:0052737 + +[Term] +id: GO:0008986 +name: pyruvate, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate." [EC:2.7.9.2, RHEA:11364] +synonym: "ATP:pyruvate, water phosphotransferase activity" EXACT [EC:2.7.9.2] +synonym: "PEP synthase activity" EXACT [] +synonym: "PEP synthetase activity" EXACT [EC:2.7.9.2] +synonym: "phoephoenolpyruvate synthetase activity" EXACT [EC:2.7.9.2] +synonym: "phosphoenolpyruvate synthase activity" EXACT [EC:2.7.9.2] +synonym: "phosphoenolpyruvic synthase activity" EXACT [EC:2.7.9.2] +synonym: "phosphopyruvate synthetase activity" EXACT [EC:2.7.9.2] +synonym: "pyruvate,water dikinase activity" EXACT [EC:2.7.9.2] +synonym: "pyruvate-water dikinase (phosphorylating)" EXACT [EC:2.7.9.2] +synonym: "water pyruvate dikinase activity" EXACT [] +xref: EC:2.7.9.2 +xref: KEGG_REACTION:R00199 +xref: MetaCyc:PEPSYNTH-RXN +xref: RHEA:11364 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0008987 +name: quinolinate synthetase A activity +namespace: molecular_function +def: "Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate." [GOC:jl, MetaCyc:QUINOLINATE-SYNTHA-RXN] +xref: MetaCyc:QUINOLINATE-SYNTHA-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +relationship: part_of GO:0019805 ! quinolinate biosynthetic process + +[Term] +id: GO:0008988 +name: rRNA (adenine-N6-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine." [EC:2.1.1.48] +synonym: "ErmC 23S rRNA methyltransferase" NARROW [EC:2.1.1.48] +synonym: "gene ksgA methyltransferase" NARROW [EC:2.1.1.48] +synonym: "ribonucleic acid-adenine (N(6)) methylase activity" EXACT [EC:2.1.1.48] +synonym: "ribonucleic acid-adenine (N6) methylase activity" EXACT [EC:2.1.1.48] +synonym: "ribosomal ribonucleate adenine 6-methyltransferase activity" EXACT [EC:2.1.1.48] +synonym: "S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.48] +synonym: "S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.48] +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity + +[Term] +id: GO:0008989 +name: rRNA (guanine-N1-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine." [GOC:curators] +synonym: "ribosomal ribonucleate guanine 1-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.51] +xref: MetaCyc:RRNA-GUANINE-N1--METHYLTRANSFERASE-RXN +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016435 ! rRNA (guanine) methyltransferase activity + +[Term] +id: GO:0008990 +name: rRNA (guanine-N2-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine." [EC:2.1.1.52] +synonym: "ribosomal ribonucleate guanine-2-methyltransferase activity" EXACT [EC:2.1.1.52] +synonym: "S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity" EXACT [EC:2.1.1.52] +synonym: "S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity" EXACT [EC:2.1.1.52] +xref: EC:2.1.1.52 +xref: MetaCyc:RRNA-GUANINE-N2--METHYLTRANSFERASE-RXN +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016435 ! rRNA (guanine) methyltransferase activity + +[Term] +id: GO:0008991 +name: obsolete serine-type signal peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism." [GOC:mah] +comment: This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products. +synonym: "serine-type signal peptidase activity" EXACT [] +xref: EC:3.4.21 +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008992 +name: obsolete repressor LexA activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA." [EC:3.4.21.88] +comment: This term was made obsolete because it represents a gene product. +synonym: "LexA repressor" RELATED [EC:3.4.21.88] +synonym: "repressor lexA" RELATED [EC:3.4.21.88] +synonym: "repressor LexA activity" EXACT [] +xref: EC:3.4.21.88 +xref: MetaCyc:3.4.21.88-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0008993 +name: rhamnulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate." [EC:2.7.1.5] +synonym: "ATP:L-rhamnulose 1-phosphotransferase activity" EXACT [EC:2.7.1.5] +synonym: "L-rhamnulokinase activity" EXACT [EC:2.7.1.5] +synonym: "L-rhamnulose kinase activity" EXACT [EC:2.7.1.5] +synonym: "rhamnulokinase (phosphorylating)" EXACT [EC:2.7.1.5] +synonym: "rhamnulose kinase activity" EXACT [EC:2.7.1.5] +synonym: "RhuK" RELATED [EC:2.7.1.5] +xref: EC:2.7.1.5 +xref: MetaCyc:RHAMNULOKIN-RXN +xref: RHEA:20117 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0008994 +name: rhamnulose-1-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde." [EC:4.1.2.19] +synonym: "L-rhamnulose 1-phosphate aldolase activity" EXACT [EC:4.1.2.19] +synonym: "L-rhamnulose-1-phosphate lactaldehyde-lyase activity" EXACT [EC:4.1.2.19] +synonym: "L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.19] +synonym: "L-rhamnulose-phosphate aldolase activity" EXACT [EC:4.1.2.19] +synonym: "rhamnulose phosphate aldolase activity" EXACT [EC:4.1.2.19] +xref: EC:4.1.2.19 +xref: MetaCyc:RHAMNULPALDOL-RXN +xref: RHEA:19689 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0008995 +name: ribonuclease E activity +namespace: molecular_function +def: "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990] +xref: MetaCyc:3.1.26.12-RXN +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0008996 +name: ribonuclease G activity +namespace: molecular_function +def: "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990] +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0008997 +name: ribonuclease R activity +namespace: molecular_function +def: "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides." [PMID:11948193] +xref: EC:3.1.11 +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0008998 +name: ribonucleoside-triphosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin." [EC:1.17.4.2] +synonym: "2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity" EXACT [EC:1.17.4.2] +synonym: "2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity" EXACT [EC:1.17.4.2] +synonym: "ribonucleotide reductase activity" BROAD [EC:1.17.4.2] +xref: EC:1.17.4.2 +xref: MetaCyc:1.17.4.2-RXN +xref: RHEA:12701 +is_a: GO:0016728 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor + +[Term] +id: GO:0008999 +name: ribosomal-protein-alanine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine." [EC:2.3.1.128] +synonym: "acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity" EXACT [EC:2.3.1.128] +synonym: "ribosomal protein S18 acetyltransferase activity" EXACT [EC:2.3.1.128] +xref: EC:2.3.1.128 +xref: MetaCyc:2.3.1.128-RXN +is_a: GO:0004596 ! peptide alpha-N-acetyltransferase activity + +[Term] +id: GO:0009000 +name: selenocysteine lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor." [EC:4.4.1.16] +synonym: "L-selenocysteine selenide-lyase (L-alanine-forming)" EXACT [EC:4.4.1.16] +synonym: "selenocysteine beta-lyase activity" EXACT [EC:4.4.1.16] +synonym: "selenocysteine reductase activity" EXACT [EC:4.4.1.16] +xref: EC:4.4.1.16 +xref: MetaCyc:SELENOCYSTEINE-LYASE-RXN +xref: Reactome:R-HSA-2408524 "Sec is reduced to H2Se by SCLY" +xref: RHEA:11632 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0009001 +name: serine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA." [EC:2.3.1.30, RHEA:24560] +synonym: "acetyl-CoA:L-serine O-acetyltransferase activity" EXACT [EC:2.3.1.30] +synonym: "L-serine acetyltransferase activity" EXACT [EC:2.3.1.30] +synonym: "SATase activity" EXACT [EC:2.3.1.30] +synonym: "serine acetyltransferase activity" EXACT [EC:2.3.1.30] +synonym: "serine transacetylase activity" EXACT [EC:2.3.1.30] +xref: EC:2.3.1.30 +xref: KEGG_REACTION:R00586 +xref: MetaCyc:SERINE-O-ACETTRAN-RXN +xref: RHEA:24560 +is_a: GO:0016412 ! serine O-acyltransferase activity +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0009002 +name: serine-type D-Ala-D-Ala carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine." [EC:3.4.16.4] +synonym: "D-alanine carboxypeptidase" BROAD [EC:3.4.16.4] +synonym: "D-alanyl carboxypeptidase activity" EXACT [EC:3.4.16.4] +synonym: "D-alanyl-D-alanine carboxypeptidase activity" EXACT [EC:3.4.16.4] +synonym: "D-alanyl-D-alanine-carboxypeptidase activity" EXACT [EC:3.4.16.4] +synonym: "D-alanyl-D-alanine-cleaving peptidase activity" EXACT [EC:3.4.16.4] +synonym: "D-alanyl-D-alanine-cleaving-peptidase activity" EXACT [EC:3.4.16.4] +synonym: "DD-carboxypeptidase" BROAD [EC:3.4.16.4] +synonym: "DD-peptidase activity" EXACT [EC:3.4.16.4] +synonym: "DD-transpeptidase activity" EXACT [EC:3.4.16.4] +xref: EC:3.4.16.4 +xref: MetaCyc:3.4.16.4-RXN +is_a: GO:0004185 ! serine-type carboxypeptidase activity + +[Term] +id: GO:0009003 +name: obsolete signal peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor." [GOC:mah] +comment: This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products. +synonym: "signal peptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0008233 + +[Term] +id: GO:0009004 +name: obsolete signal peptidase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor." [EC:3.4.21.89] +comment: This term was made obsolete because it represents a gene product. +synonym: "bacterial leader peptidase 1" RELATED [EC:3.4.21.89] +synonym: "bacterial leader peptidase I activity" NARROW [EC:3.4.21.89] +synonym: "Escherichia coli leader peptidase" NARROW [EC:3.4.21.89] +synonym: "eukaryotic signal peptidase" NARROW [EC:3.4.21.89] +synonym: "eukaryotic signal proteinase" NARROW [EC:3.4.21.89] +synonym: "HOSP" RELATED [EC:3.4.21.89] +synonym: "leader peptidase activity" EXACT [EC:3.4.21.89] +synonym: "leader peptidase I" RELATED [EC:3.4.21.89] +synonym: "leader peptide hydrolase activity" EXACT [EC:3.4.21.89] +synonym: "leader proteinase activity" EXACT [EC:3.4.21.89] +synonym: "phage-procoat-leader peptidase activity" NARROW [EC:3.4.21.89] +synonym: "pilin leader peptidase" NARROW [EC:3.4.21.89] +synonym: "prokaryotic leader peptidase" NARROW [EC:3.4.21.89] +synonym: "prokaryotic signal peptidase" NARROW [EC:3.4.21.89] +synonym: "prokaryotic signal proteinase" NARROW [EC:3.4.21.89] +synonym: "propeptidase activity" EXACT [EC:3.4.21.89] +synonym: "PuIO prepilin peptidase" NARROW [EC:3.4.21.89] +synonym: "signal peptidase I activity" EXACT [] +synonym: "signal peptide hydrolase activity" EXACT [EC:3.4.21.89] +synonym: "signal proteinase activity" EXACT [EC:3.4.21.89] +synonym: "signalase activity" EXACT [EC:3.4.21.89] +synonym: "SPase I activity" EXACT [EC:3.4.21.89] +synonym: "SPC" RELATED [EC:3.4.21.89] +xref: EC:3.4.21.89 +xref: MetaCyc:3.4.21.89-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0009005 +name: obsolete signal peptidase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group." [EC:3.4.23.36] +comment: This term was made obsolete because it represents a gene product. +synonym: "leader peptidase II" RELATED [EC:3.4.23.36] +synonym: "lipoprotein signal peptidase activity" EXACT [EC:3.4.23.36] +synonym: "premurein leader proteinase activity" EXACT [EC:3.4.23.36] +synonym: "premurein-leader peptidase activity" NARROW [EC:3.4.23.36] +synonym: "prolipoprotein signal peptidase activity" EXACT [EC:3.4.23.36] +synonym: "prolipoprotein-signal peptidase activity" EXACT [EC:3.4.23.36] +synonym: "signal peptidase II activity" EXACT [] +synonym: "SPase II activity" EXACT [EC:3.4.23.36] +xref: EC:3.4.23.36 +xref: MetaCyc:3.4.23.36-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0009006 +name: obsolete siroheme synthase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents three different molecular functions. +synonym: "sirohaem synthase activity" EXACT [] +synonym: "siroheme synthase activity" EXACT [] +is_obsolete: true +consider: GO:0004851 +consider: GO:0019354 +consider: GO:0043115 +consider: GO:0051266 + +[Term] +id: GO:0009007 +name: site-specific DNA-methyltransferase (adenine-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine." [EC:2.1.1.72] +synonym: "DNA adenine methylase" BROAD [] +synonym: "EcoRI methylase" NARROW [EC:2.1.1.37, EC:2.1.1.72] +synonym: "modification methylase activity" RELATED [EC:2.1.1.72] +synonym: "N-6 adenine-specific DNA methylase activity" EXACT [EC:2.1.1.72] +synonym: "restriction-modification system activity" RELATED [EC:2.1.1.72] +xref: EC:2.1.1.72 +xref: MetaCyc:2.1.1.72-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0009008 ! DNA-methyltransferase activity +relationship: part_of GO:0032775 ! DNA methylation on adenine + +[Term] +id: GO:0009008 +name: DNA-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to a DNA molecule." [GOC:jl, ISBN:0198506732, PMID:7862522] +synonym: "deoxyribonucleate methylase activity" EXACT [] +synonym: "deoxyribonucleate methyltransferase activity" EXACT [] +synonym: "deoxyribonucleic acid methylase activity" EXACT [] +synonym: "deoxyribonucleic acid methyltransferase activity" EXACT [] +synonym: "deoxyribonucleic acid modification methylase activity" RELATED [] +synonym: "DNA methylase" BROAD [] +synonym: "DNA methyltransferase activity" EXACT [] +synonym: "DNA transmethylase activity" EXACT [] +synonym: "Type II DNA methylase" RELATED [EC:2.1.1.37] +xref: Reactome:R-HSA-212269 "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3" +xref: Reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes" +is_a: GO:0008168 ! methyltransferase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0006306 ! DNA methylation +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0009009 +name: site-specific recombinase activity +namespace: molecular_function +def: "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences." [GOC:elh] +comment: Note that this term is not a child of 'recombinase activity ; GO:0000150' because the latter represents activities that do not break or form phosphodiester bonds. +subset: goslim_pir +is_a: GO:0000150 ! recombinase activity + +[Term] +id: GO:0009010 +name: sorbitol-6-phosphate 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.140] +synonym: "D-glucitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] +synonym: "D-sorbitol 6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] +synonym: "D-sorbitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] +synonym: "D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.140] +synonym: "glucitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] +synonym: "ketosephosphate reductase activity" EXACT [EC:1.1.1.140] +synonym: "sorbitol-6-P-dehydrogenase activity" EXACT [EC:1.1.1.140] +xref: EC:1.1.1.140 +xref: MetaCyc:SORB6PDEHYDROG-RXN +xref: RHEA:19837 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0009011 +name: starch synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1)." [EC:2.4.1.21] +synonym: "adenosine diphosphate glucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "adenosine diphosphoglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "ADP-glucose starch synthase activity" EXACT [EC:2.4.1.21] +synonym: "ADP-glucose transglucosylase activity" EXACT [EC:2.4.1.21] +synonym: "ADP-glucose--starch glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "ADPG starch synthetase activity" EXACT [EC:2.4.1.21] +synonym: "ADPG-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "ADPglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.21] +synonym: "glycogen synthase activity" EXACT [EC:2.4.1.21] +synonym: "starch (bacterial glycogen) synthase activity" NARROW [EC:2.4.1.21] +synonym: "starch synthetase activity" EXACT [EC:2.4.1.21] +xref: EC:2.4.1.21 +xref: MetaCyc:GLYCOGENSYN-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0009012 +name: aminoglycoside 3''-adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+)." [EC:2.7.7.47, RHEA:20245] +synonym: "AAD (3'')" RELATED [EC:2.7.7.47] +synonym: "ATP:streptomycin 3''-adenylyltransferase activity" NARROW [] +synonym: "streptomycin 3''-adenylyltransferase activity" NARROW [] +xref: EC:2.7.7.47 +xref: KEGG_REACTION:R02226 +xref: MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN +xref: RHEA:20245 +is_a: GO:0034068 ! aminoglycoside nucleotidyltransferase activity + +[Term] +id: GO:0009013 +name: succinate-semialdehyde dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+." [EC:1.2.1.16] +synonym: "succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))" EXACT [EC:1.2.1.16] +synonym: "succinate-semialdehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.16] +xref: EC:1.2.1.16 +xref: MetaCyc:SUCCSEMIALDDEHYDROG-RXN +xref: UM-BBD_reactionID:r0371 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0009014 +name: succinyl-diaminopimelate desuccinylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate." [EC:3.5.1.18, RHEA:22608] +synonym: "N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity" EXACT [EC:3.5.1.18] +synonym: "N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.18] +xref: EC:3.5.1.18 +xref: KEGG_REACTION:R02734 +xref: MetaCyc:SUCCDIAMINOPIMDESUCC-RXN +xref: RHEA:22608 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0009015 +name: N-succinylarginine dihydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+)." [EC:3.5.3.23, RHEA:19533] +synonym: "2-N-succinyl-L-arginine iminohydrolase (decarboxylating)" EXACT [EC:3.5.3.23] +synonym: "arginine succinylhydrolase activity" EXACT [] +synonym: "AruB" RELATED [] +synonym: "AstB" RELATED [] +synonym: "N2-succinyl-L-arginine iminohydrolase (decarboxylating)" EXACT [] +synonym: "N2-succinylarginine dihydrolase activity" EXACT [] +synonym: "SADH" RELATED [] +synonym: "succinylarginine dihydrolase activity" EXACT [] +xref: EC:3.5.3.23 +xref: KEGG_REACTION:R04189 +xref: MetaCyc:SUCCARGDIHYDRO-RXN +xref: RHEA:19533 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0009016 +name: succinyldiaminopimelate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate." [EC:2.6.1.17, RHEA:11960] +synonym: "N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.17] +synonym: "N-succinyl-L-diaminopimelic glutamic transaminase activity" EXACT [EC:2.6.1.17] +synonym: "succinyldiaminopimelate aminotransferase activity" EXACT [] +synonym: "succinyldiaminopimelate transferase activity" EXACT [EC:2.6.1.17] +xref: EC:2.6.1.17 +xref: KEGG_REACTION:R04475 +xref: MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN +xref: RHEA:11960 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0009017 +name: succinylglutamate desuccinylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate." [EC:3.5.1.96, RHEA:15169] +synonym: "AstE" RELATED [] +synonym: "N-succinyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.96] +synonym: "N2-succinylglutamate desuccinylase activity" EXACT [] +synonym: "SGDS" RELATED [] +xref: EC:3.5.1.96 +xref: KEGG_REACTION:R00411 +xref: MetaCyc:SUCCGLUDESUCC-RXN +xref: RHEA:15169 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0009018 +name: sucrose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate." [EC:2.4.1.7] +synonym: "disaccharide glucosyltransferase activity" BROAD [EC:2.4.1.7] +synonym: "sucrose glucosyltransferase activity" EXACT [EC:2.4.1.7] +synonym: "sucrose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.7] +xref: EC:2.4.1.7 +xref: MetaCyc:SUCROSE-PHOSPHORYLASE-RXN +xref: RHEA:24048 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0009019 +name: tRNA (guanine-N1-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine." [EC:2.1.1.31] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity" EXACT [EC:2.1.1.31] +synonym: "S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.31] +synonym: "transfer ribonucleate guanine 1-methyltransferase activity" EXACT [EC:2.1.1.31] +synonym: "tRNA guanine 1-methyltransferase activity" EXACT [EC:2.1.1.31] +xref: Reactome:R-HSA-6782859 "TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe)" +xref: Reactome:R-HSA-6786621 "TRMT10A methylates guanosine-9 in tRNA" +xref: Reactome:R-HSA-6787591 "TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9" +is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity + +[Term] +id: GO:0009020 +name: tRNA (guanosine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine." [EC:2.1.1.34] +synonym: "S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "transfer ribonucleate guanosine 2'-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA (Gm18) 2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA (Gm18) methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA (guanosine 2')-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA guanosine 2'-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA guanosine-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] +xref: EC:2.1.1.34 +xref: MetaCyc:2.1.1.34-RXN +xref: Reactome:R-HSA-9024161 "FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe)" +is_a: GO:0016423 ! tRNA (guanine) methyltransferase activity +is_a: GO:0106050 ! tRNA 2'-O-methyltransferase activity + +[Term] +id: GO:0009022 +name: tRNA nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate." [EC:2.7.7.56] +comment: Note that, although the enzyme to which this term refers is also known as 'ribonuclease PH', and degrades tRNA in the 3'-5' direction in vivo, the term does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. +synonym: "phosphate-dependent exonuclease activity" RELATED [EC:2.7.7.56] +synonym: "ribonuclease PH activity" EXACT [EC:2.7.7.56] +synonym: "RNase PH activity" EXACT [EC:2.7.7.56] +synonym: "tRNA:phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.56] +xref: EC:2.7.7.56 +xref: MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0009023 +name: obsolete tRNA sulfurtransferase +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide." [EC:2.8.1.4, GOC:go_curators] +synonym: "tRNA sulfurtransferase" EXACT [] +synonym: "tRNA sulphurtransferase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0034227 +consider: GO:0016783 + +[Term] +id: GO:0009024 +name: tagatose-6-phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate." [EC:2.7.1.144] +synonym: "ATP:D-tagatose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.144] +synonym: "phosphotagatokinase activity" EXACT [EC:2.7.1.144] +xref: EC:2.7.1.144 +xref: MetaCyc:TAGAKIN-RXN +xref: RHEA:12420 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0009025 +name: tagatose-bisphosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate." [EC:4.1.2.40, RHEA:22948] +synonym: "AgaY" RELATED [] +synonym: "AgaZ" RELATED [] +synonym: "D-tagatose-1,6-bisphosphate aldolase activity" EXACT [EC:4.1.2.40] +synonym: "D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.40] +synonym: "D-tagatose-1,6-bisphosphate triosephosphate lyase activity" EXACT [] +synonym: "KbaY" RELATED [] +synonym: "tagatose 1,6-diphosphate aldolase activity" EXACT [EC:4.1.2.40] +synonym: "tagatose-1,6-bisphosphate aldolase 1" EXACT [] +xref: EC:4.1.2.40 +xref: KEGG_REACTION:R01069 +xref: MetaCyc:TAGAALDOL-RXN +xref: RHEA:22948 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0009026 +name: tagaturonate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH." [EC:1.1.1.58, RHEA:17813] +synonym: "altronate dehydrogenase activity" EXACT [EC:1.1.1.58] +synonym: "altronate oxidoreductase activity" EXACT [EC:1.1.1.58] +synonym: "altronic oxidoreductase activity" EXACT [EC:1.1.1.58] +synonym: "D-altronate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.58] +synonym: "D-tagaturonate reductase activity" EXACT [EC:1.1.1.58] +synonym: "tagaturonate dehydrogenase activity" EXACT [EC:1.1.1.58] +synonym: "TagUAR" RELATED [EC:1.1.1.58] +xref: EC:1.1.1.58 +xref: KEGG_REACTION:R02555 +xref: MetaCyc:ALTRO-OXIDOREDUCT-RXN +xref: RHEA:17813 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0009027 +name: tartrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+." [EC:1.1.1.93] +synonym: "mesotartrate dehydrogenase activity" EXACT [EC:1.1.1.93] +synonym: "tartrate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.93] +xref: EC:1.1.1.93 +xref: MetaCyc:TARTRATE-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0009028 +name: tartronate-semialdehyde synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2)." [EC:4.1.1.47, RHEA:10136] +synonym: "glyoxalate carboligase activity" EXACT [EC:4.1.1.47] +synonym: "glyoxylate carbo-ligase activity" EXACT [EC:4.1.1.47] +synonym: "glyoxylate carboligase activity" EXACT [EC:4.1.1.47] +synonym: "glyoxylate carboxy-lyase (dimerizing)" EXACT [EC:4.1.1.47] +synonym: "glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)" EXACT [EC:4.1.1.47] +synonym: "glyoxylic carbo-ligase activity" EXACT [EC:4.1.1.47] +synonym: "hydroxymalonic semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] +synonym: "tartronate semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] +synonym: "tartronic semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] +xref: EC:4.1.1.47 +xref: KEGG_REACTION:R00013 +xref: MetaCyc:GLYOCARBOLIG-RXN +xref: RHEA:10136 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0009029 +name: tetraacyldisaccharide 4'-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a)." [EC:2.7.1.130, RHEA:20700] +synonym: "ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity" EXACT [EC:2.7.1.130] +synonym: "lipid-A 4'-kinase activity" RELATED [EC:2.7.1.130] +xref: EC:2.7.1.130 +xref: KEGG_REACTION:R04657 +xref: MetaCyc:TETRAACYLDISACC4KIN-RXN +xref: RHEA:20700 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0009030 +name: thiamine-phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate." [EC:2.7.4.16, RHEA:15913] +synonym: "ATP:thiamine-phosphate phosphotransferase activity" EXACT [EC:2.7.4.16] +synonym: "thiamin monophosphatase activity" EXACT [EC:2.7.4.16] +synonym: "thiamin monophosphokinase activity" EXACT [EC:2.7.4.16] +synonym: "thiamin phosphate kinase activity" EXACT [] +synonym: "thiamin-monophosphate kinase activity" EXACT [EC:2.7.4.16] +synonym: "thiamin-phosphate kinase activity" EXACT [] +synonym: "thiamine-monophosphate kinase activity" EXACT [EC:2.7.4.16] +xref: EC:2.7.4.16 +xref: KEGG_REACTION:R00617 +xref: MetaCyc:THI-P-KIN-RXN +xref: RHEA:15913 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0009032 +name: thymidine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate." [EC:2.4.2.4] +synonym: "animal growth regulators, blood platelet-derived endothelial cell growth factors" RELATED [EC:2.4.2.4] +synonym: "blood platelet-derived endothelial cell growth factor" RELATED [EC:2.4.2.4] +synonym: "deoxythymidine phosphorylase activity" EXACT [EC:2.4.2.4] +synonym: "gliostatins" RELATED [EC:2.4.2.4] +synonym: "pyrimidine deoxynucleoside phosphorylase activity" EXACT [EC:2.4.2.4] +synonym: "pyrimidine phosphorylase activity" BROAD [EC:2.4.2.4] +synonym: "thymidine-orthophosphate deoxyribosyltransferase activity" EXACT [EC:2.4.2.4] +synonym: "thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.4] +synonym: "thymidine:phosphate deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.4] +xref: EC:2.4.2.4 +xref: MetaCyc:THYM-PHOSPH-RXN +xref: RHEA:16037 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0009033 +name: trimethylamine-N-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O." [GOC:curators, RHEA:22024] +synonym: "NADH:trimethylamine-N-oxide oxidoreductase" EXACT [] +synonym: "trimethylamine N-oxide reductase" EXACT [] +synonym: "trimethylamine oxidase activity" EXACT [] +synonym: "trimethylamine oxide reductase" EXACT [] +xref: MetaCyc:TMAOREDUCT-RXN +xref: RHEA:22024 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0009034 +name: tryptophanase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate." [EC:4.1.99.1, RHEA:19553] +comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. +synonym: "L-tryptophan indole-lyase (deaminating) activity" EXACT [EC:4.1.99.1] +synonym: "L-tryptophan indole-lyase (deaminating; pyruvate forming) activity" EXACT [EC:4.1.99.1] +synonym: "L-tryptophan indole-lyase activity" EXACT [EC:4.1.99.1] +synonym: "L-tryptophanase activity" EXACT [EC:4.1.99.1] +synonym: "TNase activity" EXACT [EC:4.1.99.1] +synonym: "tryptophan catabolic process, using tryptophanase" RELATED [EC:4.1.99.1] +synonym: "tryptophan catabolism, using tryptophanase" RELATED [EC:4.1.99.1] +xref: EC:4.1.99.1 +xref: KEGG_REACTION:R00673 +xref: MetaCyc:TRYPDEG-PWY +xref: MetaCyc:TRYPTOPHAN-RXN +xref: RHEA:19553 +xref: UniPathway:UPA00332 +is_a: GO:0016830 ! carbon-carbon lyase activity +relationship: part_of GO:0006569 ! tryptophan catabolic process + +[Term] +id: GO:0009035 +name: type I site-specific deoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA." [EC:3.1.21.3, PMID:15788748] +synonym: "adenosine triphosphate-dependent deoxyribonuclease activity" EXACT [EC:3.1.21.3] +synonym: "ATP-dependent DNase activity" EXACT [EC:3.1.21.3] +synonym: "deoxyribonuclease (adenosine triphosphate-hydrolyzing)" EXACT [EC:3.1.21.3] +synonym: "deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)" EXACT [EC:3.1.21.3] +synonym: "type I restriction enzyme activity" EXACT [] +synonym: "type I site-specific deoxyribonuclease activity" EXACT [EC:3.1.21.3] +xref: EC:3.1.21.3 +xref: MetaCyc:3.1.21.3-RXN +is_a: GO:0015666 ! restriction endodeoxyribonuclease activity +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0009036 +name: type II site-specific deoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site." [EC:3.1.21.4, PMID:12654995] +synonym: "type II restriction enzyme activity" EXACT [] +xref: EC:3.1.21.4 +xref: MetaCyc:3.1.21.4-RXN +is_a: GO:0015666 ! restriction endodeoxyribonuclease activity +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0009037 +name: tyrosine-based site-specific recombinase activity +namespace: molecular_function +def: "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site." [GOC:elh, PMID:11090626] +synonym: "site-specific tyrosine recombinase activity" EXACT [] +synonym: "tyrosine recombinase" BROAD [] +is_a: GO:0008907 ! integrase activity +is_a: GO:0009009 ! site-specific recombinase activity + +[Term] +id: GO:0009038 +name: undecaprenol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate." [EC:2.7.1.66, RHEA:23752] +synonym: "ATP:undecaprenol phosphotransferase activity" EXACT [EC:2.7.1.66] +synonym: "C55-isoprenoid alcohol kinase activity" EXACT [EC:2.7.1.66] +synonym: "C55-isoprenoid alcohol phosphokinase activity" EXACT [EC:2.7.1.66] +synonym: "C55-isoprenyl alcohol phosphokinase activity" EXACT [EC:2.7.1.66] +synonym: "isoprenoid alcohol kinase (phosphorylating)" BROAD [EC:2.7.1.66] +synonym: "isoprenoid alcohol kinase activity" BROAD [EC:2.7.1.66] +synonym: "isoprenoid alcohol phosphokinase activity" BROAD [EC:2.7.1.66] +synonym: "isoprenoid-alcohol kinase activity" BROAD [EC:2.7.1.66] +synonym: "polyisoprenol kinase activity" BROAD [EC:2.7.1.66] +xref: EC:2.7.1.66 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0009039 +name: urease activity +namespace: molecular_function +def: "Catalysis of the reaction: urea + H2O = CO2 + 2 NH3." [EC:3.5.1.5, RHEA:20557] +synonym: "urea amidohydrolase activity" EXACT [EC:3.5.1.5] +xref: EC:3.5.1.5 +xref: MetaCyc:UREASE-RXN +xref: RHEA:20557 +xref: UM-BBD_reactionID:r0120 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0009040 +name: ureidoglycolate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+." [EC:1.1.1.154, PMID:23284870] +synonym: "(S)-ureidoglycolate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.154] +xref: EC:1.1.1.154 +xref: MetaCyc:R165-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0009041 +name: uridylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP." [GOC:go_curators] +xref: EC:2.7.4.22 +is_a: GO:0050145 ! nucleoside monophosphate kinase activity + +[Term] +id: GO:0009042 +name: valine-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine." [EC:2.6.1.66, RHEA:22912] +synonym: "alanine--valine transaminase activity" EXACT [EC:2.6.1.66] +synonym: "alanine-oxoisovalerate aminotransferase activity" EXACT [EC:2.6.1.66] +synonym: "L-valine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.66] +synonym: "transaminase C activity" NARROW [EC:2.6.1.66] +synonym: "valine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.66] +synonym: "valine-pyruvate aminotransferase activity" EXACT [] +xref: EC:2.6.1.66 +xref: KEGG_REACTION:R01215 +xref: MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN +xref: RHEA:22912 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0009044 +name: xylan 1,4-beta-xylosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini." [EC:3.2.1.37] +synonym: "1,4-beta-D-xylan xylohydrolase activity" EXACT [EC:3.2.1.37] +synonym: "beta-D-xylopyranosidase activity" EXACT [EC:3.2.1.37] +synonym: "beta-xylosidase activity" EXACT [EC:3.2.1.37] +synonym: "exo-1,4-beta-D-xylosidase activity" EXACT [EC:3.2.1.37] +synonym: "exo-1,4-beta-xylosidase activity" EXACT [EC:3.2.1.37] +synonym: "exo-1,4-xylosidase activity" EXACT [EC:3.2.1.37] +synonym: "xylobiase activity" EXACT [EC:3.2.1.37] +xref: EC:3.2.1.37 +xref: MetaCyc:3.2.1.37-RXN +is_a: GO:0097599 ! xylanase activity + +[Term] +id: GO:0009045 +name: xylose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylose = D-xylulose." [EC:5.3.1.5] +synonym: "D-xylose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.5] +synonym: "D-xylose isomerase activity" EXACT [EC:5.3.1.5] +synonym: "D-xylose ketoisomerase activity" EXACT [EC:5.3.1.5] +synonym: "D-xylose ketol-isomerase activity" EXACT [EC:5.3.1.5] +xref: EC:5.3.1.5 +xref: MetaCyc:XYLISOM-RXN +xref: RHEA:22816 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0009046 +name: zinc D-Ala-D-Ala carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine." [EC:3.4.17.14] +synonym: "D-alanyl-D-alanine hydrolase activity" EXACT [EC:3.4.17.14] +synonym: "D-alanyl-D-alanine-cleaving carboxypeptidase activity" EXACT [EC:3.4.17.14] +synonym: "DD-carboxypeptidase" BROAD [EC:3.4.17.14] +synonym: "DD-carboxypeptidase-transpeptidase activity" EXACT [EC:3.4.17.14] +synonym: "G enzyme" RELATED [EC:3.4.17.14] +synonym: "Zn(2+) G peptidase activity" RELATED [EC:3.4.17.14] +synonym: "Zn2+ G peptidase activity" EXACT [EC:3.4.17.14] +xref: EC:3.4.17.14 +xref: MetaCyc:3.4.17.14-RXN +is_a: GO:0004181 ! metallocarboxypeptidase activity + +[Term] +id: GO:0009047 +name: dosage compensation by hyperactivation of X chromosome +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster." [GOC:jl, GOC:mr, ISBN:0140512888, PMID:11498577, PMID:20622855, Wikipedia:XY_sex-determination_system] +is_a: GO:0007549 ! dosage compensation +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0009048 +name: dosage compensation by inactivation of X chromosome +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex." [GOC:jl, GOC:mr, GOC:pr, ISBN:0140512888, PMID:11498577, PMID:20622855, Wikipedia:XY_sex-determination_system] +synonym: "Barr body formation" RELATED [] +synonym: "chromosome inactivation" BROAD [] +synonym: "X chromosome inactivation" EXACT [] +xref: Wikipedia:X-inactivation +is_a: GO:0007549 ! dosage compensation +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0009049 +name: obsolete aspartic-type signal peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism." [GOC:mah] +comment: This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products. +synonym: "aspartic-type signal peptidase activity" EXACT [] +xref: EC:3.4.23 +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0009050 +name: glycopeptide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycopeptides, any compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide." [GOC:go_curators, ISBN:0198506732] +synonym: "glycopeptide breakdown" EXACT [] +synonym: "glycopeptide catabolism" EXACT [] +synonym: "glycopeptide degradation" EXACT [] +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0009051 +name: pentose-phosphate shunt, oxidative branch +namespace: biological_process +def: "The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2)." [ISBN:0198506732, MetaCyc:OXIDATIVEPENT-PWY] +synonym: "oxidative branch, pentose pathway" EXACT [] +synonym: "oxidative pentose phosphate pathway" EXACT [] +synonym: "pentose phosphate pathway, oxidative branch" EXACT [] +synonym: "pentose phosphate shunt, oxidative branch" EXACT [] +synonym: "pentose-phosphate pathway, oxidative branch" EXACT [] +xref: MetaCyc:OXIDATIVEPENT-PWY +is_a: GO:0006740 ! NADPH regeneration +is_a: GO:0051156 ! glucose 6-phosphate metabolic process +relationship: has_part GO:0004341 ! gluconolactonase activity +relationship: part_of GO:0006098 ! pentose-phosphate shunt + +[Term] +id: GO:0009052 +name: pentose-phosphate shunt, non-oxidative branch +namespace: biological_process +def: "The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P." [ISBN:0198506732, MetaCyc:NONOXIPENT-PWY] +synonym: "pentose phosphate pathway, non-oxidative branch" EXACT [] +synonym: "pentose phosphate shunt, non-oxidative branch" EXACT [] +synonym: "pentose-phosphate pathway, non-oxidative branch" EXACT [] +xref: MetaCyc:NONOXIPENT-PWY +xref: MetaCyc:P21-PWY +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:1901135 ! carbohydrate derivative metabolic process +relationship: has_part GO:0004750 ! ribulose-phosphate 3-epimerase activity +relationship: has_part GO:0004751 ! ribose-5-phosphate isomerase activity +relationship: has_part GO:0004801 ! sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity +relationship: has_part GO:0004802 ! transketolase activity +relationship: part_of GO:0006098 ! pentose-phosphate shunt + +[Term] +id: GO:0009055 +name: electron transfer activity +namespace: molecular_function +alt_id: GO:0009053 +alt_id: GO:0009054 +def: "Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient." [ISBN:0198506732] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "electron acceptor activity" NARROW [] +synonym: "electron carrier" RELATED [] +synonym: "electron donor activity" NARROW [] +synonym: "electron transporter activity" RELATED [] +xref: Reactome:R-HSA-1362408 "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster" +xref: Reactome:R-HSA-169260 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF" +xref: Reactome:R-HSA-2564826 "4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold" +is_a: GO:0016491 ! oxidoreductase activity +intersection_of: GO:0016491 ! oxidoreductase activity +intersection_of: part_of GO:0022900 ! electron transport chain +relationship: part_of GO:0022900 ! electron transport chain + +[Term] +id: GO:0009056 +name: catabolic process +namespace: biological_process +alt_id: GO:0044243 +alt_id: GO:0044712 +def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +synonym: "breakdown" EXACT [] +synonym: "catabolism" EXACT [] +synonym: "degradation" EXACT [] +synonym: "multicellular organismal catabolic process" NARROW [] +synonym: "single-organism catabolic process" RELATED [] +xref: Wikipedia:Catabolism +is_a: GO:0008152 ! metabolic process +created_by: jl +creation_date: 2012-10-17T15:52:35Z + +[Term] +id: GO:0009057 +name: macromolecule catabolic process +namespace: biological_process +alt_id: GO:0043285 +alt_id: GO:0044266 +def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: goslim_pir +synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "macromolecule breakdown" EXACT [] +synonym: "macromolecule catabolism" EXACT [] +synonym: "macromolecule degradation" EXACT [] +synonym: "multicellular organismal macromolecule catabolic process" NARROW [] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0009058 +name: biosynthetic process +namespace: biological_process +alt_id: GO:0044274 +alt_id: GO:0044711 +def: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_plant +synonym: "anabolism" EXACT [] +synonym: "biosynthesis" EXACT [] +synonym: "formation" BROAD [] +synonym: "multicellular organismal biosynthetic process" NARROW [] +synonym: "single-organism biosynthetic process" RELATED [] +synonym: "synthesis" EXACT [] +xref: Wikipedia:Anabolism +is_a: GO:0008152 ! metabolic process +created_by: jl +creation_date: 2012-10-17T15:52:18Z + +[Term] +id: GO:0009059 +name: macromolecule biosynthetic process +namespace: biological_process +alt_id: GO:0043284 +def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: goslim_pir +synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "macromolecule anabolism" EXACT [] +synonym: "macromolecule biosynthesis" EXACT [] +synonym: "macromolecule formation" EXACT [] +synonym: "macromolecule synthesis" EXACT [] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0009060 +name: aerobic respiration +namespace: biological_process +def: "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor." [GOC:das, GOC:jl, ISBN:0140513590] +xref: MetaCyc:PWY-3781 +xref: Wikipedia:Cellular_respiration#Aerobic_respiration +is_a: GO:0045333 ! cellular respiration + +[Term] +id: GO:0009061 +name: anaerobic respiration +namespace: biological_process +def: "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor." [GOC:das, GOC:jl, ISBN:0140513590] +xref: MetaCyc:ANARESP1-PWY +xref: Wikipedia:Anaerobic_respiration +xref: Wikipedia:Cellular_respiration#Anaerobic_respiration +is_a: GO:0045333 ! cellular respiration + +[Term] +id: GO:0009062 +name: fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:go_curators] +synonym: "fatty acid breakdown" EXACT [] +synonym: "fatty acid catabolism" EXACT [] +synonym: "fatty acid degradation" EXACT [] +xref: Wikipedia:Fatty_acid_degradation +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0009063 +name: cellular amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] +synonym: "amino acid catabolic process" EXACT [] +synonym: "cellular amino acid breakdown" EXACT [] +synonym: "cellular amino acid catabolism" EXACT [] +synonym: "cellular amino acid degradation" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0009064 +name: glutamine family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai] +synonym: "glutamine family amino acid metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0009065 +name: glutamine family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai] +synonym: "glutamine family amino acid breakdown" EXACT [] +synonym: "glutamine family amino acid catabolism" EXACT [] +synonym: "glutamine family amino acid degradation" EXACT [] +is_a: GO:0009064 ! glutamine family amino acid metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0009066 +name: aspartate family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai] +synonym: "aspartate family amino acid metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0009067 +name: aspartate family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai] +synonym: "aspartate family amino acid anabolism" EXACT [] +synonym: "aspartate family amino acid biosynthesis" EXACT [] +synonym: "aspartate family amino acid formation" EXACT [] +synonym: "aspartate family amino acid synthesis" EXACT [] +is_a: GO:0009066 ! aspartate family amino acid metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009068 +name: aspartate family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine." [GOC:ai] +synonym: "aspartate family amino acid breakdown" EXACT [] +synonym: "aspartate family amino acid catabolism" EXACT [] +synonym: "aspartate family amino acid degradation" EXACT [] +is_a: GO:0009066 ! aspartate family amino acid metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0009069 +name: serine family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai] +synonym: "serine family amino acid metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0009070 +name: serine family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai] +synonym: "serine family amino acid anabolism" EXACT [] +synonym: "serine family amino acid biosynthesis" EXACT [] +synonym: "serine family amino acid formation" EXACT [] +synonym: "serine family amino acid synthesis" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009071 +name: serine family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine." [GOC:ai] +synonym: "serine family amino acid breakdown" EXACT [] +synonym: "serine family amino acid catabolism" EXACT [] +synonym: "serine family amino acid degradation" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0009072 +name: aromatic amino acid family metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators] +synonym: "aromatic amino acid family metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0009073 +name: aromatic amino acid family biosynthetic process +namespace: biological_process +alt_id: GO:0016089 +def: "The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators] +synonym: "aromatic amino acid family anabolism" EXACT [] +synonym: "aromatic amino acid family biosynthesis" EXACT [] +synonym: "aromatic amino acid family biosynthetic process, shikimate pathway" RELATED [] +synonym: "aromatic amino acid family formation" EXACT [] +synonym: "aromatic amino acid family synthesis" EXACT [] +xref: MetaCyc:COMPLETE-ARO-PWY +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0009074 +name: aromatic amino acid family catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)." [GOC:go_curators] +synonym: "aromatic amino acid family breakdown" EXACT [] +synonym: "aromatic amino acid family catabolism" EXACT [] +synonym: "aromatic amino acid family degradation" EXACT [] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0009075 +name: obsolete histidine family amino acid metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family. +synonym: "histidine family amino acid metabolic process" EXACT [] +synonym: "histidine family amino acid metabolism" EXACT [] +is_obsolete: true +replaced_by: GO:0006547 + +[Term] +id: GO:0009076 +name: obsolete histidine family amino acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family. +synonym: "histidine family amino acid anabolism" EXACT [] +synonym: "histidine family amino acid biosynthesis" EXACT [] +synonym: "histidine family amino acid biosynthetic process" EXACT [] +synonym: "histidine family amino acid formation" EXACT [] +synonym: "histidine family amino acid synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0000105 + +[Term] +id: GO:0009077 +name: obsolete histidine family amino acid catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family. +synonym: "histidine family amino acid breakdown" EXACT [] +synonym: "histidine family amino acid catabolic process" EXACT [] +synonym: "histidine family amino acid catabolism" EXACT [] +synonym: "histidine family amino acid degradation" EXACT [] +is_obsolete: true +replaced_by: GO:0006548 + +[Term] +id: GO:0009078 +name: pyruvate family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl] +synonym: "pyruvate family amino acid metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0009079 +name: pyruvate family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl] +synonym: "pyruvate family amino acid anabolism" EXACT [] +synonym: "pyruvate family amino acid biosynthesis" EXACT [] +synonym: "pyruvate family amino acid formation" EXACT [] +synonym: "pyruvate family amino acid synthesis" EXACT [] +is_a: GO:0009078 ! pyruvate family amino acid metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009080 +name: pyruvate family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine." [GOC:jl] +synonym: "pyruvate family amino acid breakdown" EXACT [] +synonym: "pyruvate family amino acid catabolism" EXACT [] +synonym: "pyruvate family amino acid degradation" EXACT [] +is_a: GO:0009078 ! pyruvate family amino acid metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0009081 +name: branched-chain amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [GOC:ai] +synonym: "branched chain family amino acid metabolism" EXACT [GOC:ai] +is_a: GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0009082 +name: branched-chain amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [GOC:ai] +synonym: "branched chain family amino acid anabolism" EXACT [] +synonym: "branched chain family amino acid biosynthesis" EXACT [] +synonym: "branched chain family amino acid biosynthetic process" EXACT [GOC:ai] +synonym: "branched chain family amino acid formation" EXACT [] +synonym: "branched chain family amino acid synthesis" EXACT [] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0009081 ! branched-chain amino acid metabolic process + +[Term] +id: GO:0009083 +name: branched-chain amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine." [GOC:ai] +synonym: "branched chain family amino acid breakdown" EXACT [] +synonym: "branched chain family amino acid catabolic process" EXACT [GOC:ai] +synonym: "branched chain family amino acid catabolism" EXACT [] +synonym: "branched chain family amino acid degradation" EXACT [] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0009081 ! branched-chain amino acid metabolic process + +[Term] +id: GO:0009084 +name: glutamine family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:ai] +synonym: "glutamine family amino acid anabolism" EXACT [] +synonym: "glutamine family amino acid biosynthesis" EXACT [] +synonym: "glutamine family amino acid formation" EXACT [] +synonym: "glutamine family amino acid synthesis" EXACT [] +is_a: GO:0009064 ! glutamine family amino acid metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009085 +name: lysine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid." [GOC:go_curators] +synonym: "lysine anabolism" EXACT [] +synonym: "lysine biosynthesis" EXACT [] +synonym: "lysine formation" EXACT [] +synonym: "lysine synthesis" EXACT [] +xref: MetaCyc:PWY-5097 +is_a: GO:0006553 ! lysine metabolic process +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process + +[Term] +id: GO:0009086 +name: methionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "methionine anabolism" EXACT [] +synonym: "methionine biosynthesis" EXACT [] +synonym: "methionine formation" EXACT [] +synonym: "methionine synthesis" EXACT [] +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0006555 ! methionine metabolic process +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process + +[Term] +id: GO:0009087 +name: methionine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "methionine breakdown" EXACT [] +synonym: "methionine catabolism" EXACT [] +synonym: "methionine degradation" EXACT [] +xref: UM-BBD_pathwayID:met +is_a: GO:0000098 ! sulfur amino acid catabolic process +is_a: GO:0006555 ! methionine metabolic process +is_a: GO:0009068 ! aspartate family amino acid catabolic process + +[Term] +id: GO:0009088 +name: threonine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +synonym: "threonine anabolism" EXACT [] +synonym: "threonine biosynthesis" EXACT [] +synonym: "threonine formation" EXACT [] +synonym: "threonine synthesis" EXACT [] +xref: MetaCyc:HOMOSER-THRESYN-PWY +xref: MetaCyc:THRESYN-PWY +is_a: GO:0006566 ! threonine metabolic process +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process + +[Term] +id: GO:0009089 +name: lysine biosynthetic process via diaminopimelate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate." [GOC:go_curators] +synonym: "diaminopimelate pathway" EXACT [] +synonym: "diaminopimelic acid pathway" EXACT [] +synonym: "lysine anabolism via diaminopimelate" EXACT [] +synonym: "lysine biosynthesis via diaminopimelic acid" EXACT [] +synonym: "lysine biosynthetic process via diaminopimelic acid" EXACT [] +synonym: "lysine formation via diaminopimelate" EXACT [] +synonym: "lysine synthesis via diaminopimelate" EXACT [] +is_a: GO:0009085 ! lysine biosynthetic process +is_a: GO:0046451 ! diaminopimelate metabolic process + +[Term] +id: GO:0009090 +name: homoserine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732] +synonym: "homoserine anabolism" EXACT [] +synonym: "homoserine biosynthesis" EXACT [] +synonym: "homoserine formation" EXACT [] +synonym: "homoserine synthesis" EXACT [] +xref: MetaCyc:HOMOSERSYN-PWY +is_a: GO:0009070 ! serine family amino acid biosynthetic process +is_a: GO:0009092 ! homoserine metabolic process + +[Term] +id: GO:0009091 +name: homoserine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid." [GOC:go_curators, ISBN:0198506732] +synonym: "homoserine breakdown" EXACT [] +synonym: "homoserine catabolism" EXACT [] +synonym: "homoserine degradation" EXACT [] +xref: MetaCyc:HOMOCYSDEGR-PWY +is_a: GO:0009071 ! serine family amino acid catabolic process +is_a: GO:0009092 ! homoserine metabolic process + +[Term] +id: GO:0009092 +name: homoserine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine." [GOC:go_curators, ISBN:0198506732] +synonym: "homoserine metabolism" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process + +[Term] +id: GO:0009093 +name: cysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators] +synonym: "cysteine breakdown" EXACT [] +synonym: "cysteine catabolism" EXACT [] +synonym: "cysteine degradation" EXACT [] +xref: Wikipedia:Cysteine +is_a: GO:0000098 ! sulfur amino acid catabolic process +is_a: GO:0006534 ! cysteine metabolic process +is_a: GO:0009071 ! serine family amino acid catabolic process + +[Term] +id: GO:0009094 +name: L-phenylalanine biosynthetic process +namespace: biological_process +alt_id: GO:0019274 +alt_id: GO:0019275 +def: "The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid." [GOC:jsg, GOC:mah] +synonym: "L-phenylalanine anabolism" EXACT [] +synonym: "L-phenylalanine biosynthesis" EXACT [] +synonym: "L-phenylalanine formation" EXACT [] +synonym: "L-phenylalanine synthesis" EXACT [] +synonym: "phenylalanine biosynthesis" BROAD [] +synonym: "phenylalanine biosynthetic process" BROAD [] +synonym: "phenylalanine biosynthetic process, prephenate pathway" RELATED [] +synonym: "phenylalanine biosynthetic process, shikimate pathway" RELATED [] +is_a: GO:0006558 ! L-phenylalanine metabolic process +is_a: GO:0009095 ! aromatic amino acid family biosynthetic process, prephenate pathway +is_a: GO:1902223 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + +[Term] +id: GO:0009095 +name: aromatic amino acid family biosynthetic process, prephenate pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate." [GOC:mah, ISBN:0471331309] +synonym: "aromatic amino acid family anabolism, prephenate pathway" EXACT [] +synonym: "aromatic amino acid family biosynthetic process via prephenate" EXACT [GOC:pr] +synonym: "aromatic amino acid family biosynthetic process via prephenate(2-)" EXACT [GOC:pr] +synonym: "aromatic amino acid family formation, prephenate pathway" EXACT [] +synonym: "aromatic amino acid family synthesis, prephenate pathway" EXACT [] +is_a: GO:0009073 ! aromatic amino acid family biosynthetic process + +[Term] +id: GO:0009097 +name: isoleucine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai] +synonym: "isoleucine anabolism" EXACT [] +synonym: "isoleucine biosynthesis" EXACT [] +synonym: "isoleucine formation" EXACT [] +synonym: "isoleucine synthesis" EXACT [] +xref: MetaCyc:ILEUSYN-PWY +is_a: GO:0006549 ! isoleucine metabolic process +is_a: GO:0009082 ! branched-chain amino acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009098 +name: leucine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid." [GOC:ai] +synonym: "leucine anabolism" EXACT [] +synonym: "leucine biosynthesis" EXACT [] +synonym: "leucine formation" EXACT [] +synonym: "leucine synthesis" EXACT [] +xref: MetaCyc:LEUSYN-PWY +is_a: GO:0006551 ! leucine metabolic process +is_a: GO:0009082 ! branched-chain amino acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0009099 +name: valine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid." [GOC:ai] +synonym: "valine anabolism" EXACT [] +synonym: "valine biosynthesis" EXACT [] +synonym: "valine formation" EXACT [] +synonym: "valine synthesis" EXACT [] +xref: MetaCyc:VALSYN-PWY +is_a: GO:0006573 ! valine metabolic process +is_a: GO:0009082 ! branched-chain amino acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +relationship: has_part GO:0003984 ! acetolactate synthase activity +relationship: has_part GO:0004160 ! dihydroxy-acid dehydratase activity +relationship: has_part GO:0004455 ! ketol-acid reductoisomerase activity +relationship: has_part GO:0052655 ! L-valine transaminase activity + +[Term] +id: GO:0009100 +name: glycoprotein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] +subset: goslim_drosophila +synonym: "glycoprotein metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0044260 ! cellular macromolecule metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0009101 +name: glycoprotein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] +synonym: "glycoprotein anabolism" EXACT [] +synonym: "glycoprotein biosynthesis" EXACT [] +synonym: "glycoprotein formation" EXACT [] +synonym: "glycoprotein synthesis" EXACT [] +is_a: GO:0009100 ! glycoprotein metabolic process +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0009102 +name: biotin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid." [ISBN:0198506732] +synonym: "biotin anabolism" EXACT [] +synonym: "biotin biosynthesis" EXACT [] +synonym: "biotin formation" EXACT [] +synonym: "biotin synthesis" EXACT [] +synonym: "vitamin B7 biosynthesis" EXACT [] +synonym: "vitamin B7 biosynthetic process" EXACT [] +synonym: "vitamin H biosynthesis" EXACT [] +synonym: "vitamin H biosynthetic process" EXACT [] +xref: MetaCyc:BIOTIN-SYNTHESIS-PWY +is_a: GO:0006768 ! biotin metabolic process +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0009103 +name: lipopolysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria." [GOC:ai, GOC:mr] +synonym: "lipopolysaccharide anabolism" EXACT [] +synonym: "lipopolysaccharide biosynthesis" EXACT [] +synonym: "lipopolysaccharide formation" EXACT [] +synonym: "lipopolysaccharide synthesis" EXACT [] +synonym: "LPS biosynthetic process" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0008653 ! lipopolysaccharide metabolic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009104 +name: lipopolysaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria." [GOC:ai] +synonym: "lipopolysaccharide breakdown" EXACT [] +synonym: "lipopolysaccharide catabolism" EXACT [] +synonym: "lipopolysaccharide degradation" EXACT [] +synonym: "LPS catabolic process" EXACT [] +is_a: GO:0008653 ! lipopolysaccharide metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0009106 +name: lipoate metabolic process +namespace: biological_process +alt_id: GO:0000273 +def: "The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid." [GOC:ai, ISBN:0198506732] +synonym: "lipoate metabolism" EXACT [] +synonym: "lipoic acid metabolic process" EXACT [] +synonym: "lipoic acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0009107 +name: lipoate biosynthetic process +namespace: biological_process +alt_id: GO:0009105 +def: "The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid." [GOC:ai, ISBN:0198506732] +synonym: "lipoate anabolism" EXACT [] +synonym: "lipoate biosynthesis" EXACT [] +synonym: "lipoate formation" EXACT [] +synonym: "lipoate synthesis" EXACT [] +synonym: "lipoic acid anabolism" EXACT [] +synonym: "lipoic acid biosynthesis" EXACT [] +synonym: "lipoic acid biosynthetic process" EXACT [] +synonym: "lipoic acid formation" EXACT [] +synonym: "lipoic acid synthesis" EXACT [] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0009106 ! lipoate metabolic process +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0009108 +name: coenzyme biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai] +synonym: "coenzyme anabolism" EXACT [] +synonym: "coenzyme and prosthetic group biosynthesis" BROAD [] +synonym: "coenzyme and prosthetic group biosynthetic process" BROAD [] +synonym: "coenzyme biosynthesis" EXACT [] +synonym: "coenzyme formation" EXACT [] +synonym: "coenzyme synthesis" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0009109 +name: coenzyme catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai] +synonym: "coenzyme and prosthetic group catabolic process" BROAD [] +synonym: "coenzyme and prosthetic group catabolism" BROAD [] +synonym: "coenzyme breakdown" EXACT [] +synonym: "coenzyme catabolism" EXACT [] +synonym: "coenzyme degradation" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0009110 +name: vitamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:go_curators, ISBN:0198506732] +synonym: "vitamin anabolism" EXACT [] +synonym: "vitamin biosynthesis" EXACT [] +synonym: "vitamin formation" EXACT [] +synonym: "vitamin synthesis" EXACT [] +is_a: GO:0006766 ! vitamin metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process + +[Term] +id: GO:0009111 +name: vitamin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] +synonym: "vitamin breakdown" EXACT [] +synonym: "vitamin catabolism" EXACT [] +synonym: "vitamin degradation" EXACT [] +is_a: GO:0006766 ! vitamin metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044282 ! small molecule catabolic process + +[Term] +id: GO:0009112 +name: nucleobase metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] +synonym: "nucleobase metabolism" EXACT [] +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0009113 +name: purine nucleobase biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine." [ISBN:0198506732] +synonym: "purine base anabolism" EXACT [] +synonym: "purine base biosynthesis" EXACT [] +synonym: "purine base biosynthetic process" EXACT [GOC:go_curators] +synonym: "purine base formation" EXACT [] +synonym: "purine base synthesis" EXACT [] +xref: MetaCyc:PWY-841 +is_a: GO:0006144 ! purine nucleobase metabolic process +is_a: GO:0046112 ! nucleobase biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0009114 +name: hypoxanthine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate." [GOC:go_curators] +synonym: "hypoxanthine breakdown" EXACT [] +synonym: "hypoxanthine catabolism" EXACT [] +synonym: "hypoxanthine degradation" EXACT [] +is_a: GO:0006145 ! purine nucleobase catabolic process +is_a: GO:0046100 ! hypoxanthine metabolic process + +[Term] +id: GO:0009115 +name: xanthine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids." [GOC:go_curators] +synonym: "xanthine breakdown" EXACT [] +synonym: "xanthine catabolism" EXACT [] +synonym: "xanthine degradation" EXACT [] +is_a: GO:0006145 ! purine nucleobase catabolic process +is_a: GO:0046110 ! xanthine metabolic process + +[Term] +id: GO:0009116 +name: nucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine)." [GOC:ma] +subset: goslim_pir +synonym: "nucleoside metabolism" EXACT [] +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901657 ! glycosyl compound metabolic process + +[Term] +id: GO:0009117 +name: nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates)." [GOC:ma] +subset: goslim_pir +synonym: "nucleotide metabolism" EXACT [] +is_a: GO:0006753 ! nucleoside phosphate metabolic process + +[Term] +id: GO:0009118 +name: regulation of nucleoside metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] +synonym: "regulation of nucleoside metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009116 ! nucleoside metabolic process +relationship: regulates GO:0009116 ! nucleoside metabolic process + +[Term] +id: GO:0009119 +name: ribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:jl] +synonym: "ribonucleoside metabolism" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process + +[Term] +id: GO:0009120 +name: deoxyribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713] +synonym: "deoxyribonucleoside metabolism" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process + +[Term] +id: GO:0009123 +name: nucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside monophosphate metabolism" EXACT [] +is_a: GO:0006753 ! nucleoside phosphate metabolic process + +[Term] +id: GO:0009124 +name: nucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside monophosphate anabolism" EXACT [] +synonym: "nucleoside monophosphate biosynthesis" EXACT [] +synonym: "nucleoside monophosphate formation" EXACT [] +synonym: "nucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process +is_a: GO:1901293 ! nucleoside phosphate biosynthetic process + +[Term] +id: GO:0009125 +name: nucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside monophosphate breakdown" EXACT [] +synonym: "nucleoside monophosphate catabolism" EXACT [] +synonym: "nucleoside monophosphate degradation" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process +is_a: GO:1901292 ! nucleoside phosphate catabolic process + +[Term] +id: GO:0009126 +name: purine nucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process + +[Term] +id: GO:0009127 +name: purine nucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside monophosphate anabolism" EXACT [] +synonym: "purine nucleoside monophosphate biosynthesis" EXACT [] +synonym: "purine nucleoside monophosphate formation" EXACT [] +synonym: "purine nucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009124 ! nucleoside monophosphate biosynthetic process +is_a: GO:0009126 ! purine nucleoside monophosphate metabolic process + +[Term] +id: GO:0009128 +name: purine nucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside monophosphate breakdown" EXACT [] +synonym: "purine nucleoside monophosphate catabolism" EXACT [] +synonym: "purine nucleoside monophosphate degradation" EXACT [] +is_a: GO:0009125 ! nucleoside monophosphate catabolic process +is_a: GO:0009126 ! purine nucleoside monophosphate metabolic process + +[Term] +id: GO:0009129 +name: pyrimidine nucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process + +[Term] +id: GO:0009130 +name: pyrimidine nucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside monophosphate anabolism" EXACT [] +synonym: "pyrimidine nucleoside monophosphate biosynthesis" EXACT [] +synonym: "pyrimidine nucleoside monophosphate formation" EXACT [] +synonym: "pyrimidine nucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009124 ! nucleoside monophosphate biosynthetic process +is_a: GO:0009129 ! pyrimidine nucleoside monophosphate metabolic process + +[Term] +id: GO:0009131 +name: pyrimidine nucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside monophosphate breakdown" EXACT [] +synonym: "pyrimidine nucleoside monophosphate catabolism" EXACT [] +synonym: "pyrimidine nucleoside monophosphate degradation" EXACT [] +is_a: GO:0009125 ! nucleoside monophosphate catabolic process +is_a: GO:0009129 ! pyrimidine nucleoside monophosphate metabolic process + +[Term] +id: GO:0009132 +name: nucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside diphosphate metabolism" EXACT [] +is_a: GO:0006753 ! nucleoside phosphate metabolic process + +[Term] +id: GO:0009133 +name: nucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside diphosphate anabolism" EXACT [] +synonym: "nucleoside diphosphate biosynthesis" EXACT [] +synonym: "nucleoside diphosphate formation" EXACT [] +synonym: "nucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process +is_a: GO:1901293 ! nucleoside phosphate biosynthetic process + +[Term] +id: GO:0009134 +name: nucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside diphosphate breakdown" EXACT [] +synonym: "nucleoside diphosphate catabolism" EXACT [] +synonym: "nucleoside diphosphate degradation" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process +is_a: GO:1901292 ! nucleoside phosphate catabolic process + +[Term] +id: GO:0009135 +name: purine nucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process + +[Term] +id: GO:0009136 +name: purine nucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside diphosphate anabolism" EXACT [] +synonym: "purine nucleoside diphosphate biosynthesis" EXACT [] +synonym: "purine nucleoside diphosphate formation" EXACT [] +synonym: "purine nucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009133 ! nucleoside diphosphate biosynthetic process +is_a: GO:0009135 ! purine nucleoside diphosphate metabolic process + +[Term] +id: GO:0009137 +name: purine nucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside diphosphate breakdown" EXACT [] +synonym: "purine nucleoside diphosphate catabolism" EXACT [] +synonym: "purine nucleoside diphosphate degradation" EXACT [] +is_a: GO:0009134 ! nucleoside diphosphate catabolic process +is_a: GO:0009135 ! purine nucleoside diphosphate metabolic process + +[Term] +id: GO:0009138 +name: pyrimidine nucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process + +[Term] +id: GO:0009139 +name: pyrimidine nucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside diphosphate anabolism" EXACT [] +synonym: "pyrimidine nucleoside diphosphate biosynthesis" EXACT [] +synonym: "pyrimidine nucleoside diphosphate formation" EXACT [] +synonym: "pyrimidine nucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009133 ! nucleoside diphosphate biosynthetic process +is_a: GO:0009138 ! pyrimidine nucleoside diphosphate metabolic process + +[Term] +id: GO:0009140 +name: pyrimidine nucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside diphosphate breakdown" EXACT [] +synonym: "pyrimidine nucleoside diphosphate catabolism" EXACT [] +synonym: "pyrimidine nucleoside diphosphate degradation" EXACT [] +is_a: GO:0009134 ! nucleoside diphosphate catabolic process +is_a: GO:0009138 ! pyrimidine nucleoside diphosphate metabolic process + +[Term] +id: GO:0009141 +name: nucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside triphosphate metabolism" EXACT [] +is_a: GO:0006753 ! nucleoside phosphate metabolic process + +[Term] +id: GO:0009142 +name: nucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside triphosphate anabolism" EXACT [] +synonym: "nucleoside triphosphate biosynthesis" EXACT [] +synonym: "nucleoside triphosphate formation" EXACT [] +synonym: "nucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process +is_a: GO:1901293 ! nucleoside phosphate biosynthetic process + +[Term] +id: GO:0009143 +name: nucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "nucleoside triphosphate breakdown" EXACT [] +synonym: "nucleoside triphosphate catabolism" EXACT [] +synonym: "nucleoside triphosphate degradation" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process +is_a: GO:1901292 ! nucleoside phosphate catabolic process + +[Term] +id: GO:0009144 +name: purine nucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process + +[Term] +id: GO:0009145 +name: purine nucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside triphosphate anabolism" EXACT [] +synonym: "purine nucleoside triphosphate biosynthesis" EXACT [] +synonym: "purine nucleoside triphosphate formation" EXACT [] +synonym: "purine nucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009142 ! nucleoside triphosphate biosynthetic process +is_a: GO:0009144 ! purine nucleoside triphosphate metabolic process + +[Term] +id: GO:0009146 +name: purine nucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine nucleoside triphosphate breakdown" EXACT [] +synonym: "purine nucleoside triphosphate catabolism" EXACT [] +synonym: "purine nucleoside triphosphate degradation" EXACT [] +is_a: GO:0009143 ! nucleoside triphosphate catabolic process +is_a: GO:0009144 ! purine nucleoside triphosphate metabolic process + +[Term] +id: GO:0009147 +name: pyrimidine nucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process + +[Term] +id: GO:0009148 +name: pyrimidine nucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside triphosphate anabolism" EXACT [] +synonym: "pyrimidine nucleoside triphosphate biosynthesis" EXACT [] +synonym: "pyrimidine nucleoside triphosphate formation" EXACT [] +synonym: "pyrimidine nucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009142 ! nucleoside triphosphate biosynthetic process +is_a: GO:0009147 ! pyrimidine nucleoside triphosphate metabolic process + +[Term] +id: GO:0009149 +name: pyrimidine nucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine nucleoside triphosphate breakdown" EXACT [] +synonym: "pyrimidine nucleoside triphosphate catabolism" EXACT [] +synonym: "pyrimidine nucleoside triphosphate degradation" EXACT [] +is_a: GO:0009143 ! nucleoside triphosphate catabolic process +is_a: GO:0009147 ! pyrimidine nucleoside triphosphate metabolic process + +[Term] +id: GO:0009150 +name: purine ribonucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleotide metabolism" EXACT [] +is_a: GO:0006163 ! purine nucleotide metabolic process +is_a: GO:0009259 ! ribonucleotide metabolic process + +[Term] +id: GO:0009151 +name: purine deoxyribonucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleotide metabolism" EXACT [] +is_a: GO:0006163 ! purine nucleotide metabolic process +is_a: GO:0009394 ! 2'-deoxyribonucleotide metabolic process + +[Term] +id: GO:0009152 +name: purine ribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleotide anabolism" EXACT [] +synonym: "purine ribonucleotide biosynthesis" EXACT [] +synonym: "purine ribonucleotide formation" EXACT [] +synonym: "purine ribonucleotide synthesis" EXACT [] +is_a: GO:0006164 ! purine nucleotide biosynthetic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009260 ! ribonucleotide biosynthetic process + +[Term] +id: GO:0009153 +name: purine deoxyribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleotide anabolism" EXACT [] +synonym: "purine deoxyribonucleotide biosynthesis" EXACT [] +synonym: "purine deoxyribonucleotide formation" EXACT [] +synonym: "purine deoxyribonucleotide synthesis" EXACT [] +is_a: GO:0006164 ! purine nucleotide biosynthetic process +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009265 ! 2'-deoxyribonucleotide biosynthetic process + +[Term] +id: GO:0009154 +name: purine ribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleotide breakdown" EXACT [] +synonym: "purine ribonucleotide catabolism" EXACT [] +synonym: "purine ribonucleotide degradation" EXACT [] +is_a: GO:0006195 ! purine nucleotide catabolic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009261 ! ribonucleotide catabolic process + +[Term] +id: GO:0009155 +name: purine deoxyribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleotide breakdown" EXACT [] +synonym: "purine deoxyribonucleotide catabolism" EXACT [] +synonym: "purine deoxyribonucleotide degradation" EXACT [] +is_a: GO:0006195 ! purine nucleotide catabolic process +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009264 ! deoxyribonucleotide catabolic process +is_a: GO:0046386 ! deoxyribose phosphate catabolic process + +[Term] +id: GO:0009156 +name: ribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside monophosphate anabolism" EXACT [] +synonym: "ribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "ribonucleoside monophosphate formation" EXACT [] +synonym: "ribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009124 ! nucleoside monophosphate biosynthetic process +is_a: GO:0009161 ! ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009157 +name: deoxyribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside monophosphate anabolism" EXACT [] +synonym: "deoxyribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "deoxyribonucleoside monophosphate formation" EXACT [] +synonym: "deoxyribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009124 ! nucleoside monophosphate biosynthetic process +is_a: GO:0009162 ! deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009158 +name: ribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside monophosphate breakdown" EXACT [] +synonym: "ribonucleoside monophosphate catabolism" EXACT [] +synonym: "ribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009125 ! nucleoside monophosphate catabolic process +is_a: GO:0009161 ! ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009159 +name: deoxyribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside monophosphate breakdown" EXACT [] +synonym: "deoxyribonucleoside monophosphate catabolism" EXACT [] +synonym: "deoxyribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009125 ! nucleoside monophosphate catabolic process +is_a: GO:0009162 ! deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009161 +name: ribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process + +[Term] +id: GO:0009162 +name: deoxyribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process + +[Term] +id: GO:0009163 +name: nucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713] +synonym: "nucleoside anabolism" EXACT [] +synonym: "nucleoside biosynthesis" EXACT [] +synonym: "nucleoside formation" EXACT [] +synonym: "nucleoside synthesis" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process +is_a: GO:0034404 ! nucleobase-containing small molecule biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901659 ! glycosyl compound biosynthetic process + +[Term] +id: GO:0009164 +name: nucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl] +synonym: "nucleoside breakdown" EXACT [] +synonym: "nucleoside catabolism" EXACT [] +synonym: "nucleoside degradation" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process +is_a: GO:0034656 ! nucleobase-containing small molecule catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901658 ! glycosyl compound catabolic process + +[Term] +id: GO:0009165 +name: nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)." [GOC:go_curators] +synonym: "nucleotide anabolism" EXACT [] +synonym: "nucleotide biosynthesis" EXACT [] +synonym: "nucleotide formation" EXACT [] +synonym: "nucleotide synthesis" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:1901293 ! nucleoside phosphate biosynthetic process + +[Term] +id: GO:0009166 +name: nucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)." [GOC:go_curators] +synonym: "nucleotide breakdown" EXACT [] +synonym: "nucleotide catabolism" EXACT [] +synonym: "nucleotide degradation" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:1901292 ! nucleoside phosphate catabolic process + +[Term] +id: GO:0009167 +name: purine ribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009126 ! purine nucleoside monophosphate metabolic process +is_a: GO:0009161 ! ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009168 +name: purine ribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside monophosphate anabolism" EXACT [] +synonym: "purine ribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "purine ribonucleoside monophosphate formation" EXACT [] +synonym: "purine ribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009127 ! purine nucleoside monophosphate biosynthetic process +is_a: GO:0009156 ! ribonucleoside monophosphate biosynthetic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009169 +name: purine ribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside monophosphate breakdown" EXACT [] +synonym: "purine ribonucleoside monophosphate catabolism" EXACT [] +synonym: "purine ribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009128 ! purine nucleoside monophosphate catabolic process +is_a: GO:0009158 ! ribonucleoside monophosphate catabolic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009170 +name: purine deoxyribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009126 ! purine nucleoside monophosphate metabolic process +is_a: GO:0009162 ! deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009171 +name: purine deoxyribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside monophosphate anabolism" EXACT [] +synonym: "purine deoxyribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "purine deoxyribonucleoside monophosphate formation" EXACT [] +synonym: "purine deoxyribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009127 ! purine nucleoside monophosphate biosynthetic process +is_a: GO:0009157 ! deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0009170 ! purine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009172 +name: purine deoxyribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside monophosphate breakdown" EXACT [] +synonym: "purine deoxyribonucleoside monophosphate catabolism" EXACT [] +synonym: "purine deoxyribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009128 ! purine nucleoside monophosphate catabolic process +is_a: GO:0009159 ! deoxyribonucleoside monophosphate catabolic process +is_a: GO:0009170 ! purine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009173 +name: pyrimidine ribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009129 ! pyrimidine nucleoside monophosphate metabolic process +is_a: GO:0009161 ! ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009174 +name: pyrimidine ribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside monophosphate anabolism" EXACT [] +synonym: "pyrimidine ribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "pyrimidine ribonucleoside monophosphate formation" EXACT [] +synonym: "pyrimidine ribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009130 ! pyrimidine nucleoside monophosphate biosynthetic process +is_a: GO:0009156 ! ribonucleoside monophosphate biosynthetic process +is_a: GO:0009173 ! pyrimidine ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009175 +name: pyrimidine ribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside monophosphate breakdown" EXACT [] +synonym: "pyrimidine ribonucleoside monophosphate catabolism" EXACT [] +synonym: "pyrimidine ribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009131 ! pyrimidine nucleoside monophosphate catabolic process +is_a: GO:0009158 ! ribonucleoside monophosphate catabolic process +is_a: GO:0009173 ! pyrimidine ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009176 +name: pyrimidine deoxyribonucleoside monophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside monophosphate metabolism" EXACT [] +is_a: GO:0009129 ! pyrimidine nucleoside monophosphate metabolic process +is_a: GO:0009162 ! deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009177 +name: pyrimidine deoxyribonucleoside monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside monophosphate anabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside monophosphate biosynthesis" EXACT [] +synonym: "pyrimidine deoxyribonucleoside monophosphate formation" EXACT [] +synonym: "pyrimidine deoxyribonucleoside monophosphate synthesis" EXACT [] +is_a: GO:0009130 ! pyrimidine nucleoside monophosphate biosynthetic process +is_a: GO:0009157 ! deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0009176 ! pyrimidine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009178 +name: pyrimidine deoxyribonucleoside monophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside monophosphate breakdown" EXACT [] +synonym: "pyrimidine deoxyribonucleoside monophosphate catabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside monophosphate degradation" EXACT [] +is_a: GO:0009131 ! pyrimidine nucleoside monophosphate catabolic process +is_a: GO:0009159 ! deoxyribonucleoside monophosphate catabolic process +is_a: GO:0009176 ! pyrimidine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0009179 +name: purine ribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009135 ! purine nucleoside diphosphate metabolic process +is_a: GO:0009185 ! ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009180 +name: purine ribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside diphosphate anabolism" EXACT [] +synonym: "purine ribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "purine ribonucleoside diphosphate formation" EXACT [] +synonym: "purine ribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009136 ! purine nucleoside diphosphate biosynthetic process +is_a: GO:0009179 ! purine ribonucleoside diphosphate metabolic process +is_a: GO:0009188 ! ribonucleoside diphosphate biosynthetic process + +[Term] +id: GO:0009181 +name: purine ribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside diphosphate breakdown" EXACT [] +synonym: "purine ribonucleoside diphosphate catabolism" EXACT [] +synonym: "purine ribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009137 ! purine nucleoside diphosphate catabolic process +is_a: GO:0009179 ! purine ribonucleoside diphosphate metabolic process +is_a: GO:0009191 ! ribonucleoside diphosphate catabolic process + +[Term] +id: GO:0009182 +name: purine deoxyribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009135 ! purine nucleoside diphosphate metabolic process +is_a: GO:0009186 ! deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009183 +name: purine deoxyribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside diphosphate anabolism" EXACT [] +synonym: "purine deoxyribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "purine deoxyribonucleoside diphosphate formation" EXACT [] +synonym: "purine deoxyribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009136 ! purine nucleoside diphosphate biosynthetic process +is_a: GO:0009182 ! purine deoxyribonucleoside diphosphate metabolic process +is_a: GO:0009189 ! deoxyribonucleoside diphosphate biosynthetic process + +[Term] +id: GO:0009184 +name: purine deoxyribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside diphosphate breakdown" EXACT [] +synonym: "purine deoxyribonucleoside diphosphate catabolism" EXACT [] +synonym: "purine deoxyribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009137 ! purine nucleoside diphosphate catabolic process +is_a: GO:0009182 ! purine deoxyribonucleoside diphosphate metabolic process +is_a: GO:0009192 ! deoxyribonucleoside diphosphate catabolic process + +[Term] +id: GO:0009185 +name: ribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process + +[Term] +id: GO:0009186 +name: deoxyribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009132 ! nucleoside diphosphate metabolic process + +[Term] +id: GO:0009187 +name: cyclic nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732] +synonym: "cyclic nucleotide metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0009188 +name: ribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside diphosphate anabolism" EXACT [] +synonym: "ribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "ribonucleoside diphosphate formation" EXACT [] +synonym: "ribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009133 ! nucleoside diphosphate biosynthetic process +is_a: GO:0009185 ! ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009189 +name: deoxyribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside diphosphate anabolism" EXACT [] +synonym: "deoxyribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "deoxyribonucleoside diphosphate formation" EXACT [] +synonym: "deoxyribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009133 ! nucleoside diphosphate biosynthetic process +is_a: GO:0009186 ! deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009190 +name: cyclic nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732] +synonym: "cyclic nucleotide anabolism" EXACT [] +synonym: "cyclic nucleotide biosynthesis" EXACT [] +synonym: "cyclic nucleotide formation" EXACT [] +synonym: "cyclic nucleotide synthesis" EXACT [] +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0009187 ! cyclic nucleotide metabolic process + +[Term] +id: GO:0009191 +name: ribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside diphosphate breakdown" EXACT [] +synonym: "ribonucleoside diphosphate catabolism" EXACT [] +synonym: "ribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009134 ! nucleoside diphosphate catabolic process +is_a: GO:0009185 ! ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009192 +name: deoxyribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside diphosphate breakdown" EXACT [] +synonym: "deoxyribonucleoside diphosphate catabolism" EXACT [] +synonym: "deoxyribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009134 ! nucleoside diphosphate catabolic process +is_a: GO:0009186 ! deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009193 +name: pyrimidine ribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009138 ! pyrimidine nucleoside diphosphate metabolic process +is_a: GO:0009185 ! ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009194 +name: pyrimidine ribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside diphosphate anabolism" EXACT [] +synonym: "pyrimidine ribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "pyrimidine ribonucleoside diphosphate formation" EXACT [] +synonym: "pyrimidine ribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009139 ! pyrimidine nucleoside diphosphate biosynthetic process +is_a: GO:0009188 ! ribonucleoside diphosphate biosynthetic process +is_a: GO:0009193 ! pyrimidine ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009195 +name: pyrimidine ribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside diphosphate breakdown" EXACT [] +synonym: "pyrimidine ribonucleoside diphosphate catabolism" EXACT [] +synonym: "pyrimidine ribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009140 ! pyrimidine nucleoside diphosphate catabolic process +is_a: GO:0009191 ! ribonucleoside diphosphate catabolic process +is_a: GO:0009193 ! pyrimidine ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009196 +name: pyrimidine deoxyribonucleoside diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside diphosphate metabolism" EXACT [] +is_a: GO:0009138 ! pyrimidine nucleoside diphosphate metabolic process +is_a: GO:0009186 ! deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009197 +name: pyrimidine deoxyribonucleoside diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside diphosphate anabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside diphosphate biosynthesis" EXACT [] +synonym: "pyrimidine deoxyribonucleoside diphosphate formation" EXACT [] +synonym: "pyrimidine deoxyribonucleoside diphosphate synthesis" EXACT [] +is_a: GO:0009139 ! pyrimidine nucleoside diphosphate biosynthetic process +is_a: GO:0009189 ! deoxyribonucleoside diphosphate biosynthetic process +is_a: GO:0009196 ! pyrimidine deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009198 +name: pyrimidine deoxyribonucleoside diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside diphosphate breakdown" EXACT [] +synonym: "pyrimidine deoxyribonucleoside diphosphate catabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside diphosphate degradation" EXACT [] +is_a: GO:0009140 ! pyrimidine nucleoside diphosphate catabolic process +is_a: GO:0009192 ! deoxyribonucleoside diphosphate catabolic process +is_a: GO:0009196 ! pyrimidine deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0009199 +name: ribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process + +[Term] +id: GO:0009200 +name: deoxyribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009141 ! nucleoside triphosphate metabolic process + +[Term] +id: GO:0009201 +name: ribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside triphosphate anabolism" EXACT [] +synonym: "ribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "ribonucleoside triphosphate formation" EXACT [] +synonym: "ribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009142 ! nucleoside triphosphate biosynthetic process +is_a: GO:0009199 ! ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009202 +name: deoxyribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside triphosphate anabolism" EXACT [] +synonym: "deoxyribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "deoxyribonucleoside triphosphate formation" EXACT [] +synonym: "deoxyribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009142 ! nucleoside triphosphate biosynthetic process +is_a: GO:0009200 ! deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009203 +name: ribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleoside triphosphate breakdown" EXACT [] +synonym: "ribonucleoside triphosphate catabolism" EXACT [] +synonym: "ribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009143 ! nucleoside triphosphate catabolic process +is_a: GO:0009199 ! ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009204 +name: deoxyribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleoside triphosphate breakdown" EXACT [] +synonym: "deoxyribonucleoside triphosphate catabolism" EXACT [] +synonym: "deoxyribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009143 ! nucleoside triphosphate catabolic process +is_a: GO:0009200 ! deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009205 +name: purine ribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009144 ! purine nucleoside triphosphate metabolic process +is_a: GO:0009199 ! ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009206 +name: purine ribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside triphosphate anabolism" EXACT [] +synonym: "purine ribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "purine ribonucleoside triphosphate formation" EXACT [] +synonym: "purine ribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009145 ! purine nucleoside triphosphate biosynthetic process +is_a: GO:0009201 ! ribonucleoside triphosphate biosynthetic process +is_a: GO:0009205 ! purine ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009207 +name: purine ribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine ribonucleoside triphosphate breakdown" EXACT [] +synonym: "purine ribonucleoside triphosphate catabolism" EXACT [] +synonym: "purine ribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009146 ! purine nucleoside triphosphate catabolic process +is_a: GO:0009203 ! ribonucleoside triphosphate catabolic process +is_a: GO:0009205 ! purine ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009208 +name: pyrimidine ribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009147 ! pyrimidine nucleoside triphosphate metabolic process +is_a: GO:0009199 ! ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009209 +name: pyrimidine ribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside triphosphate anabolism" EXACT [] +synonym: "pyrimidine ribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "pyrimidine ribonucleoside triphosphate formation" EXACT [] +synonym: "pyrimidine ribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009148 ! pyrimidine nucleoside triphosphate biosynthetic process +is_a: GO:0009201 ! ribonucleoside triphosphate biosynthetic process +is_a: GO:0009208 ! pyrimidine ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009210 +name: pyrimidine ribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleoside triphosphate breakdown" EXACT [] +synonym: "pyrimidine ribonucleoside triphosphate catabolism" EXACT [] +synonym: "pyrimidine ribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009149 ! pyrimidine nucleoside triphosphate catabolic process +is_a: GO:0009203 ! ribonucleoside triphosphate catabolic process +is_a: GO:0009208 ! pyrimidine ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009211 +name: pyrimidine deoxyribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009147 ! pyrimidine nucleoside triphosphate metabolic process +is_a: GO:0009200 ! deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009212 +name: pyrimidine deoxyribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside triphosphate anabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "pyrimidine deoxyribonucleoside triphosphate formation" EXACT [] +synonym: "pyrimidine deoxyribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009148 ! pyrimidine nucleoside triphosphate biosynthetic process +is_a: GO:0009202 ! deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0009211 ! pyrimidine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009213 +name: pyrimidine deoxyribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleoside triphosphate breakdown" EXACT [] +synonym: "pyrimidine deoxyribonucleoside triphosphate catabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009149 ! pyrimidine nucleoside triphosphate catabolic process +is_a: GO:0009204 ! deoxyribonucleoside triphosphate catabolic process +is_a: GO:0009211 ! pyrimidine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009214 +name: cyclic nucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732] +synonym: "cyclic nucleotide breakdown" EXACT [] +synonym: "cyclic nucleotide catabolism" EXACT [] +synonym: "cyclic nucleotide degradation" EXACT [] +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0009187 ! cyclic nucleotide metabolic process + +[Term] +id: GO:0009215 +name: purine deoxyribonucleoside triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside triphosphate metabolism" EXACT [] +is_a: GO:0009144 ! purine nucleoside triphosphate metabolic process +is_a: GO:0009200 ! deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009216 +name: purine deoxyribonucleoside triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside triphosphate anabolism" EXACT [] +synonym: "purine deoxyribonucleoside triphosphate biosynthesis" EXACT [] +synonym: "purine deoxyribonucleoside triphosphate formation" EXACT [] +synonym: "purine deoxyribonucleoside triphosphate synthesis" EXACT [] +is_a: GO:0009145 ! purine nucleoside triphosphate biosynthetic process +is_a: GO:0009202 ! deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0009215 ! purine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009217 +name: purine deoxyribonucleoside triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "purine deoxyribonucleoside triphosphate breakdown" EXACT [] +synonym: "purine deoxyribonucleoside triphosphate catabolism" EXACT [] +synonym: "purine deoxyribonucleoside triphosphate degradation" EXACT [] +is_a: GO:0009146 ! purine nucleoside triphosphate catabolic process +is_a: GO:0009204 ! deoxyribonucleoside triphosphate catabolic process +is_a: GO:0009215 ! purine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0009218 +name: pyrimidine ribonucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleotide metabolism" EXACT [] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0009259 ! ribonucleotide metabolic process + +[Term] +id: GO:0009219 +name: pyrimidine deoxyribonucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleotide metabolism" EXACT [] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0009394 ! 2'-deoxyribonucleotide metabolic process + +[Term] +id: GO:0009220 +name: pyrimidine ribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleotide anabolism" EXACT [] +synonym: "pyrimidine ribonucleotide biosynthesis" EXACT [] +synonym: "pyrimidine ribonucleotide formation" EXACT [] +synonym: "pyrimidine ribonucleotide synthesis" EXACT [] +xref: MetaCyc:PWY0-162 +is_a: GO:0006221 ! pyrimidine nucleotide biosynthetic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process +is_a: GO:0009260 ! ribonucleotide biosynthetic process + +[Term] +id: GO:0009221 +name: pyrimidine deoxyribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleotide anabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleotide biosynthesis" EXACT [] +synonym: "pyrimidine deoxyribonucleotide formation" EXACT [] +synonym: "pyrimidine deoxyribonucleotide synthesis" EXACT [] +xref: MetaCyc:PWY0-166 +is_a: GO:0006221 ! pyrimidine nucleotide biosynthetic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process +is_a: GO:0009265 ! 2'-deoxyribonucleotide biosynthetic process + +[Term] +id: GO:0009222 +name: pyrimidine ribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine ribonucleotide breakdown" EXACT [] +synonym: "pyrimidine ribonucleotide catabolism" EXACT [] +synonym: "pyrimidine ribonucleotide degradation" EXACT [] +is_a: GO:0006244 ! pyrimidine nucleotide catabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process +is_a: GO:0009261 ! ribonucleotide catabolic process + +[Term] +id: GO:0009223 +name: pyrimidine deoxyribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "pyrimidine deoxyribonucleotide breakdown" EXACT [] +synonym: "pyrimidine deoxyribonucleotide catabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleotide degradation" EXACT [] +is_a: GO:0006244 ! pyrimidine nucleotide catabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process +is_a: GO:0009264 ! deoxyribonucleotide catabolic process +is_a: GO:0046386 ! deoxyribose phosphate catabolic process + +[Term] +id: GO:0009224 +name: CMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate." [ISBN:0198506732] +synonym: "CMP anabolism" EXACT [] +synonym: "CMP biosynthesis" EXACT [] +synonym: "CMP formation" EXACT [] +synonym: "CMP synthesis" EXACT [] +is_a: GO:0009174 ! pyrimidine ribonucleoside monophosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046035 ! CMP metabolic process + +[Term] +id: GO:0009225 +name: nucleotide-sugar metabolic process +namespace: biological_process +def: "The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732] +subset: goslim_pir +synonym: "nucleotide-sugar metabolism" EXACT [] +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14587 xsd:anyURI + +[Term] +id: GO:0009226 +name: nucleotide-sugar biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732] +synonym: "nucleotide-sugar anabolism" EXACT [] +synonym: "nucleotide-sugar biosynthesis" EXACT [] +synonym: "nucleotide-sugar formation" EXACT [] +synonym: "nucleotide-sugar synthesis" EXACT [] +is_a: GO:0009225 ! nucleotide-sugar metabolic process +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009227 +name: nucleotide-sugar catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732] +synonym: "nucleotide-sugar breakdown" EXACT [] +synonym: "nucleotide-sugar catabolism" EXACT [] +synonym: "nucleotide-sugar degradation" EXACT [] +is_a: GO:0009225 ! nucleotide-sugar metabolic process +is_a: GO:0034656 ! nucleobase-containing small molecule catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0009228 +name: thiamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:jl, ISBN:0198506732] +synonym: "thiamin anabolism" EXACT [] +synonym: "thiamin biosynthetic process" EXACT [] +synonym: "thiamine biosynthesis" EXACT [] +synonym: "thiamine formation" EXACT [] +synonym: "thiamine synthesis" EXACT [] +synonym: "vitamin B1 biosynthesis" EXACT [] +synonym: "vitamin B1 biosynthetic process" EXACT [] +xref: MetaCyc:THISYN-PWY +is_a: GO:0006772 ! thiamine metabolic process +is_a: GO:0042724 ! thiamine-containing compound biosynthetic process + +[Term] +id: GO:0009229 +name: thiamine diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle." [GOC:jl, ISBN:0140512713] +synonym: "thiamin diphosphate biosynthetic process" EXACT [GOC:cuators] +synonym: "thiamin pyrophosphate biosynthesis" EXACT [] +synonym: "thiamin pyrophosphate biosynthetic process" EXACT [] +synonym: "thiamine diphosphate anabolism" EXACT [] +synonym: "thiamine diphosphate biosynthesis" EXACT [] +synonym: "thiamine diphosphate formation" EXACT [] +synonym: "thiamine diphosphate synthesis" EXACT [] +synonym: "thiamine pyrophosphate biosynthesis" EXACT [] +synonym: "thiamine pyrophosphate biosynthetic process" EXACT [] +synonym: "TPP biosynthesis" EXACT [] +synonym: "TPP biosynthetic process" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042357 ! thiamine diphosphate metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0009230 +name: thiamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:jl, ISBN:0198506732] +synonym: "thiamin catabolic process" EXACT [] +synonym: "thiamine breakdown" EXACT [] +synonym: "thiamine catabolism" EXACT [] +synonym: "thiamine degradation" EXACT [] +synonym: "vitamin B1 catabolic process" EXACT [] +synonym: "vitamin B1 catabolism" EXACT [] +is_a: GO:0006772 ! thiamine metabolic process +is_a: GO:0042725 ! thiamine-containing compound catabolic process + +[Term] +id: GO:0009231 +name: riboflavin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "riboflavin anabolism" EXACT [] +synonym: "riboflavin biosynthesis" EXACT [] +synonym: "riboflavin formation" EXACT [] +synonym: "riboflavin synthesis" EXACT [] +synonym: "vitamin B2 biosynthesis" EXACT [] +synonym: "vitamin B2 biosynthetic process" EXACT [] +synonym: "vitamin G biosynthesis" EXACT [] +synonym: "vitamin G biosynthetic process" EXACT [] +xref: MetaCyc:RIBOSYN2-PWY +xref: Wikipedia:Riboflavin +is_a: GO:0006771 ! riboflavin metabolic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0042727 ! flavin-containing compound biosynthetic process + +[Term] +id: GO:0009232 +name: riboflavin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "riboflavin breakdown" EXACT [] +synonym: "riboflavin catabolism" EXACT [] +synonym: "riboflavin degradation" EXACT [] +synonym: "vitamin B2 catabolic process" EXACT [] +synonym: "vitamin B2 catabolism" EXACT [] +synonym: "vitamin G catabolic process" EXACT [] +synonym: "vitamin G catabolism" EXACT [] +is_a: GO:0006771 ! riboflavin metabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042728 ! flavin-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0009233 +name: menaquinone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "menaquinone metabolism" EXACT [] +synonym: "menatetrenone metabolic process" EXACT [] +synonym: "menatetrenone metabolism" EXACT [] +synonym: "multiprenylmenaquinone metabolic process" EXACT [] +synonym: "multiprenylmenaquinone metabolism" EXACT [] +synonym: "vitamin K2 metabolic process" EXACT [] +synonym: "vitamin K2 metabolism" EXACT [] +is_a: GO:1901661 ! quinone metabolic process + +[Term] +id: GO:0009234 +name: menaquinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "menaquinone anabolism" EXACT [] +synonym: "menaquinone biosynthesis" EXACT [] +synonym: "menaquinone formation" EXACT [] +synonym: "menaquinone synthesis" EXACT [] +synonym: "menatetrenone biosynthesis" EXACT [] +synonym: "menatetrenone biosynthetic process" EXACT [] +synonym: "multiprenylmenaquinone biosynthesis" EXACT [] +synonym: "multiprenylmenaquinone biosynthetic process" EXACT [] +synonym: "vitamin K2 biosynthesis" EXACT [] +synonym: "vitamin K2 biosynthetic process" EXACT [] +xref: MetaCyc:MENAQUINONESYN-PWY +is_a: GO:0009233 ! menaquinone metabolic process +is_a: GO:1901663 ! quinone biosynthetic process + +[Term] +id: GO:0009235 +name: cobalamin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:go_curators] +synonym: "cobalamin metabolism" EXACT [] +synonym: "vitamin B12 metabolic process" EXACT [] +synonym: "vitamin B12 metabolism" EXACT [] +synonym: "vitamin B12 reduction" NARROW [] +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0009236 +name: cobalamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:jl, ISBN:0198506732] +synonym: "cobalamin anabolism" EXACT [] +synonym: "cobalamin biosynthesis" EXACT [] +synonym: "cobalamin formation" EXACT [] +synonym: "cobalamin synthesis" EXACT [] +synonym: "vitamin B12 biosynthesis" EXACT [] +synonym: "vitamin B12 biosynthetic process" EXACT [] +is_a: GO:0009235 ! cobalamin metabolic process +is_a: GO:0033014 ! tetrapyrrole biosynthetic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0009237 +name: siderophore metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action." [ISBN:0198547684] +synonym: "siderochrome metabolic process" NARROW [] +synonym: "siderochrome metabolism" NARROW [] +synonym: "siderophore metabolism" EXACT [] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0009238 +name: enterobactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway." [ISBN:0198547684] +synonym: "enterobactin metabolism" EXACT [] +synonym: "enterochelin metabolic process" EXACT [] +synonym: "enterochelin metabolism" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0009239 +name: enterobactin biosynthetic process +namespace: biological_process +alt_id: GO:0031191 +alt_id: GO:0031192 +def: "The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway." [GOC:go_curators] +synonym: "enterobactin anabolism" EXACT [] +synonym: "enterobactin biosynthesis" EXACT [] +synonym: "enterobactin biosynthetic process, peptide formation" NARROW [] +synonym: "enterobactin biosynthetic process, peptide modification" NARROW [] +synonym: "enterobactin formation" EXACT [] +synonym: "enterobactin synthesis" EXACT [] +synonym: "enterobactin synthetase" RELATED [] +synonym: "enterochelin biosynthesis" EXACT [] +synonym: "enterochelin biosynthetic process" EXACT [] +xref: MetaCyc:ENTBACSYN-PWY +is_a: GO:0009238 ! enterobactin metabolic process +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019540 ! siderophore biosynthetic process from catechol + +[Term] +id: GO:0009240 +name: isopentenyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids." [GOC:jl, ISBN:0198506732] +synonym: "IPP biosynthesis" EXACT [] +synonym: "IPP biosynthetic process" EXACT [] +synonym: "isopentenyl diphosphate anabolism" EXACT [] +synonym: "isopentenyl diphosphate biosynthesis" EXACT [] +synonym: "isopentenyl diphosphate formation" EXACT [] +synonym: "isopentenyl diphosphate synthesis" EXACT [] +synonym: "isopentenyl pyrophosphate biosynthesis" EXACT [] +synonym: "isopentenyl pyrophosphate biosynthetic process" EXACT [] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0046490 ! isopentenyl diphosphate metabolic process +relationship: part_of GO:0008299 ! isoprenoid biosynthetic process + +[Term] +id: GO:0009242 +name: colanic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide." [GOC:ai] +synonym: "colanic acid anabolism" EXACT [] +synonym: "colanic acid biosynthesis" EXACT [] +synonym: "colanic acid formation" EXACT [] +synonym: "colanic acid synthesis" EXACT [] +synonym: "M antigen biosynthesis" EXACT [] +synonym: "M antigen biosynthetic process" EXACT [] +xref: MetaCyc:COLANSYN-PWY +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0046377 ! colanic acid metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009243 +name: O antigen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide." [ISBN:0198506732] +synonym: "O antigen anabolism" EXACT [] +synonym: "O antigen biosynthesis" EXACT [] +synonym: "O antigen formation" EXACT [] +synonym: "O antigen synthesis" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0046402 ! O antigen metabolic process +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0009244 +name: lipopolysaccharide core region biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues." [ISBN:0198506732] +synonym: "lipopolysaccharide core region anabolism" EXACT [] +synonym: "lipopolysaccharide core region biosynthesis" EXACT [] +synonym: "lipopolysaccharide core region formation" EXACT [] +synonym: "lipopolysaccharide core region synthesis" EXACT [] +synonym: "LPS core region biosynthetic process" EXACT [] +is_a: GO:0009312 ! oligosaccharide biosynthetic process +is_a: GO:0046401 ! lipopolysaccharide core region metabolic process +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0009245 +name: lipid A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common." [ISBN:0198506732, PMID:20974832, PMID:22216004] +synonym: "lipid A anabolism" EXACT [] +synonym: "lipid A biosynthesis" EXACT [] +synonym: "lipid A formation" EXACT [] +synonym: "lipid A synthesis" EXACT [] +xref: MetaCyc:NAGLIPASYN-PWY +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0046493 ! lipid A metabolic process +is_a: GO:1901271 ! lipooligosaccharide biosynthetic process + +[Term] +id: GO:0009246 +name: enterobacterial common antigen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria." [GOC:ma] +synonym: "enterobacterial common antigen anabolism" EXACT [] +synonym: "enterobacterial common antigen biosynthesis" EXACT [] +synonym: "enterobacterial common antigen formation" EXACT [] +synonym: "enterobacterial common antigen synthesis" EXACT [] +xref: MetaCyc:ECASYN-PWY +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0046378 ! enterobacterial common antigen metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009247 +name: glycolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." [GOC:go_curators] +synonym: "glycolipid anabolism" EXACT [] +synonym: "glycolipid biosynthesis" EXACT [] +synonym: "glycolipid formation" EXACT [] +synonym: "glycolipid synthesis" EXACT [] +xref: MetaCyc:PWY-401 +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0046467 ! membrane lipid biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009248 +name: K antigen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens." [ISBN:0198506732] +synonym: "K antigen anabolism" EXACT [] +synonym: "K antigen biosynthesis" EXACT [] +synonym: "K antigen formation" EXACT [] +synonym: "K antigen synthesis" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0046375 ! K antigen metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009249 +name: protein lipoylation +namespace: biological_process +alt_id: GO:0018055 +def: "The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine." [RESID:AA0118] +synonym: "peptidyl-lysine lipoylation" EXACT [] +synonym: "protein-lipoic acid cofactor linkage" EXACT [] +is_a: GO:0018065 ! protein-cofactor linkage +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0009250 +name: glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] +synonym: "glucan anabolism" EXACT [] +synonym: "glucan biosynthesis" EXACT [] +synonym: "glucan formation" EXACT [] +synonym: "glucan synthesis" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process + +[Term] +id: GO:0009251 +name: glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] +synonym: "glucan breakdown" EXACT [] +synonym: "glucan catabolism" EXACT [] +synonym: "glucan degradation" EXACT [] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0044042 ! glucan metabolic process + +[Term] +id: GO:0009252 +name: peptidoglycan biosynthetic process +namespace: biological_process +alt_id: GO:0009285 +def: "The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls." [http://www.dsmz.de/species/murein.htm, ISBN:0198506732] +synonym: "murein biosynthesis" EXACT [] +synonym: "murein biosynthetic process" EXACT [] +synonym: "peptidoglycan anabolism" EXACT [] +synonym: "peptidoglycan biosynthesis" EXACT [] +synonym: "peptidoglycan formation" EXACT [] +synonym: "peptidoglycan synthesis" EXACT [] +is_a: GO:0000270 ! peptidoglycan metabolic process +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process +relationship: part_of GO:0009273 ! peptidoglycan-based cell wall biogenesis + +[Term] +id: GO:0009253 +name: peptidoglycan catabolic process +namespace: biological_process +alt_id: GO:0009286 +def: "The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls." [http://www.dsmz.de/species/murein.htm, ISBN:0198506732] +synonym: "murein catabolic process" EXACT [] +synonym: "murein catabolism" EXACT [] +synonym: "peptidoglycan breakdown" EXACT [] +synonym: "peptidoglycan catabolism" EXACT [] +synonym: "peptidoglycan degradation" EXACT [] +is_a: GO:0000270 ! peptidoglycan metabolic process +is_a: GO:0006027 ! glycosaminoglycan catabolic process + +[Term] +id: GO:0009254 +name: peptidoglycan turnover +namespace: biological_process +alt_id: GO:0009287 +def: "The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall." [GOC:jl] +synonym: "murein turnover" EXACT [] +is_a: GO:0000270 ! peptidoglycan metabolic process + +[Term] +id: GO:0009255 +name: Entner-Doudoroff pathway through 6-phosphogluconate +namespace: biological_process +def: "A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it." [GOC:jl, MetaCyc:ENTNER-DOUDOROFF-PWY-I, PMID:12921356, PMID:12981024] +xref: MetaCyc:ENTNER-DOUDOROFF-PWY-I +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0061678 ! Entner-Doudoroff pathway +relationship: has_part GO:0004456 ! phosphogluconate dehydratase activity + +[Term] +id: GO:0009256 +name: 10-formyltetrahydrofolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai] +synonym: "10-formyl-THF metabolic process" EXACT [] +synonym: "10-formyl-THF metabolism" EXACT [] +synonym: "10-formyltetrahydrofolate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0046653 ! tetrahydrofolate metabolic process + +[Term] +id: GO:0009257 +name: 10-formyltetrahydrofolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai] +synonym: "10-formyl-THF biosynthesis" EXACT [] +synonym: "10-formyl-THF biosynthetic process" EXACT [] +synonym: "10-formyltetrahydrofolate anabolism" EXACT [] +synonym: "10-formyltetrahydrofolate biosynthesis" EXACT [] +synonym: "10-formyltetrahydrofolate formation" EXACT [] +synonym: "10-formyltetrahydrofolate synthesis" EXACT [] +xref: MetaCyc:1CMET2-PWY +xref: MetaCyc:PWY-3841 +is_a: GO:0009256 ! 10-formyltetrahydrofolate metabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046654 ! tetrahydrofolate biosynthetic process + +[Term] +id: GO:0009258 +name: 10-formyltetrahydrofolate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate." [GOC:ai] +synonym: "10-formyl-THF catabolic process" EXACT [] +synonym: "10-formyl-THF catabolism" EXACT [] +synonym: "10-formyltetrahydrofolate breakdown" EXACT [] +synonym: "10-formyltetrahydrofolate catabolism" EXACT [] +synonym: "10-formyltetrahydrofolate degradation" EXACT [] +is_a: GO:0009256 ! 10-formyltetrahydrofolate metabolic process +is_a: GO:0009397 ! folic acid-containing compound catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0009259 +name: ribonucleotide metabolic process +namespace: biological_process +alt_id: GO:0009121 +def: "The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleotide metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0019693 ! ribose phosphate metabolic process + +[Term] +id: GO:0009260 +name: ribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleotide anabolism" EXACT [] +synonym: "ribonucleotide biosynthesis" EXACT [] +synonym: "ribonucleotide formation" EXACT [] +synonym: "ribonucleotide synthesis" EXACT [] +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0009259 ! ribonucleotide metabolic process +is_a: GO:0046390 ! ribose phosphate biosynthetic process + +[Term] +id: GO:0009261 +name: ribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "ribonucleotide breakdown" EXACT [] +synonym: "ribonucleotide catabolism" EXACT [] +synonym: "ribonucleotide degradation" EXACT [] +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0009259 ! ribonucleotide metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0009262 +name: deoxyribonucleotide metabolic process +namespace: biological_process +alt_id: GO:0009122 +alt_id: GO:0009393 +def: "The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleotide metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0009263 +name: deoxyribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleotide anabolism" EXACT [] +synonym: "deoxyribonucleotide biosynthesis" EXACT [] +synonym: "deoxyribonucleotide formation" EXACT [] +synonym: "deoxyribonucleotide synthesis" EXACT [] +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0009262 ! deoxyribonucleotide metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0009264 +name: deoxyribonucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:go_curators, ISBN:0198506732] +synonym: "deoxyribonucleotide breakdown" EXACT [] +synonym: "deoxyribonucleotide catabolism" EXACT [] +synonym: "deoxyribonucleotide degradation" EXACT [] +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0009262 ! deoxyribonucleotide metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0009265 +name: 2'-deoxyribonucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:mah] +synonym: "2'-deoxyribonucleotide anabolism" EXACT [] +synonym: "2'-deoxyribonucleotide biosynthesis" EXACT [] +synonym: "2'-deoxyribonucleotide formation" EXACT [] +synonym: "2'-deoxyribonucleotide synthesis" EXACT [] +is_a: GO:0009263 ! deoxyribonucleotide biosynthetic process +is_a: GO:0009394 ! 2'-deoxyribonucleotide metabolic process +is_a: GO:0046385 ! deoxyribose phosphate biosynthetic process + +[Term] +id: GO:0009266 +name: response to temperature stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." [GOC:hb] +synonym: "response to thermal stimulus" EXACT [] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0009267 +name: cellular response to starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment." [GOC:jl] +is_a: GO:0031669 ! cellular response to nutrient levels +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0042594 ! response to starvation + +[Term] +id: GO:0009268 +name: response to pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:jl, Wikipedia:PH] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0009269 +name: response to desiccation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." [GOC:jl] +synonym: "desiccation tolerance" RELATED [] +is_a: GO:0009414 ! response to water deprivation + +[Term] +id: GO:0009270 +name: response to humidity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere." [GOC:jl] +is_a: GO:0009415 ! response to water + +[Term] +id: GO:0009271 +name: phage shock +namespace: biological_process +def: "A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage." [GOC:add, GOC:jl, PMID:15485810, PMID:16045608] +is_a: GO:0006950 ! response to stress +is_a: GO:0098586 ! cellular response to virus +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0009272 +name: fungal-type cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin." [GOC:go_curators, GOC:mtg_sensu] +synonym: "chitin- and beta-glucan-containing cell wall biogenesis" NARROW [GOC:mah] +synonym: "fungal-type cell wall anabolism" RELATED [GOC:mah] +synonym: "fungal-type cell wall biosynthetic process" RELATED [GOC:mah] +synonym: "fungal-type cell wall formation" RELATED [GOC:mah] +synonym: "fungal-type cell wall synthesis" RELATED [GOC:mah] +is_a: GO:0042546 ! cell wall biogenesis +is_a: GO:0071852 ! fungal-type cell wall organization or biogenesis + +[Term] +id: GO:0009273 +name: peptidoglycan-based cell wall biogenesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli." [GOC:go_curators] +synonym: "cell envelope biosynthesis" BROAD [] +synonym: "cell envelope biosynthetic process" BROAD [] +synonym: "cell wall anabolism" BROAD [] +synonym: "cell wall assembly" BROAD [] +synonym: "cell wall biosynthetic process" BROAD [] +synonym: "cell wall formation" BROAD [] +synonym: "cell wall synthesis" BROAD [] +is_a: GO:0042546 ! cell wall biogenesis + +[Term] +id: GO:0009274 +name: peptidoglycan-based cell wall +namespace: cellular_component +def: "A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli." [GOC:mlg, ISBN:0815108893] +synonym: "envelope" BROAD [] +synonym: "murein sacculus" RELATED [] +synonym: "peptidoglycan" NARROW [] +is_a: GO:0005618 ! cell wall + +[Term] +id: GO:0009275 +name: Gram-positive-bacterium-type cell wall +namespace: cellular_component +def: "A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria." [GOC:mlg, ISBN:0815108893] +synonym: "20-80nm peptidoglycan-based cell wall" EXACT [] +synonym: "cell wall of Gram-positive Bacteria" EXACT [] +is_a: GO:0009274 ! peptidoglycan-based cell wall + +[Term] +id: GO:0009276 +name: Gram-negative-bacterium-type cell wall +namespace: cellular_component +def: "The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain." [GOC:mlg, ISBN:0815108893] +subset: goslim_metagenomics +synonym: "1-2nm peptidoglycan-based cell wall" EXACT [] +synonym: "cell wall inner membrane" EXACT [] +is_a: GO:0009274 ! peptidoglycan-based cell wall +relationship: part_of GO:0030313 ! cell envelope + +[Term] +id: GO:0009277 +name: fungal-type cell wall +namespace: cellular_component +def: "A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure." [GOC:mcc, GOC:mtg_sensu, ISBN:3540601864, PMID:11283274, PMID:16927300, PMID:3319422] +synonym: "beta-glucan-containing cell wall" RELATED [] +synonym: "chitin- and beta-glucan-containing cell wall" NARROW [] +synonym: "chitin-containing cell wall" RELATED [] +is_a: GO:0005618 ! cell wall + +[Term] +id: GO:0009278 +name: obsolete murein sacculus +namespace: cellular_component +def: "OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria." [GOC:ma] +comment: This term was made obsolete because it was defined inaccurately. +synonym: "murein sacculus" EXACT [] +is_obsolete: true +consider: GO:0009276 + +[Term] +id: GO:0009279 +name: cell outer membrane +namespace: cellular_component +def: "A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures." [GOC:md, GOC:mtg_sensu, ISBN:0135712254] +comment: To annotate the plasma (cytoplasmic) membrane, see instead GO:0005886. +synonym: "outer membrane of cell" EXACT [] +is_a: GO:0019867 ! outer membrane +intersection_of: GO:0019867 ! outer membrane +intersection_of: part_of GO:0030313 ! cell envelope +relationship: part_of GO:0030312 ! external encapsulating structure +relationship: part_of GO:0030313 ! cell envelope + +[Term] +id: GO:0009280 +name: obsolete cell wall inner membrane +namespace: cellular_component +def: "OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus." [GOC:ma] +comment: This term was made obsolete because it was defined inaccurately. +synonym: "cell wall inner membrane" EXACT [] +synonym: "cytoplasmic membrane" BROAD [] +is_obsolete: true +consider: GO:0009276 + +[Term] +id: GO:0009288 +name: bacterial-type flagellum +namespace: cellular_component +def: "A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope." [GOC:cilia, GOC:jh2, GOC:krc, GOC:mtg_sensu, http:en.wikipedia.org/wiki/Flagellum#Bacterial, PMID:7787060] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "flagellin-based flagellum" EXACT [] +is_a: GO:0042995 ! cell projection +is_a: GO:0043228 ! non-membrane-bounded organelle + +[Term] +id: GO:0009289 +name: pilus +namespace: cellular_component +def: "A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter." [GOC:pamgo_curators] +subset: goslim_pir +synonym: "fimbria" EXACT [] +synonym: "fimbriae" EXACT [] +synonym: "fimbrium" EXACT [] +synonym: "pili" EXACT [] +xref: Wikipedia:Pilus +is_a: GO:0042995 ! cell projection + +[Term] +id: GO:0009290 +name: DNA import into cell involved in transformation +namespace: biological_process +def: "The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell." [GOC:ai] +synonym: "cellular DNA import during transformation" RELATED [] +synonym: "cellular DNA uptake" BROAD [] +synonym: "DNA import into cell" BROAD [] +synonym: "DNA import into cell involved in transformation" RELATED [GOC:dph, GOC:tb] +synonym: "DNA transport into cell during transformation" RELATED [] +is_a: GO:0051027 ! DNA transport +is_a: GO:0098657 ! import into cell +relationship: part_of GO:0009294 ! DNA mediated transformation + +[Term] +id: GO:0009291 +name: unidirectional conjugation +namespace: biological_process +def: "The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in prokaryotes." [ISBN:0387520546] +is_a: GO:0000746 ! conjugation +is_a: GO:0009292 ! genetic transfer + +[Term] +id: GO:0009292 +name: genetic transfer +namespace: biological_process +def: "In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual." [GOC:clt] +comment: GO:0009292 should not be used for annotation of phage lysogeny (integration of the bacteriophage nucleic acid into the host bacterium's genome). +subset: goslim_pir +synonym: "genetic exchange" BROAD [] +is_a: GO:0044764 ! multi-organism cellular process +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0009293 +name: transduction +namespace: biological_process +def: "The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector." [ISBN:0198506732] +xref: Wikipedia:Transduction_(genetics) +is_a: GO:0009292 ! genetic transfer + +[Term] +id: GO:0009294 +name: DNA mediated transformation +namespace: biological_process +def: "The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material." [ISBN:0716720094, Wikipedia:Transformation_(genetics)] +synonym: "DNA-mediated transformation" EXACT [] +is_a: GO:0009292 ! genetic transfer + +[Term] +id: GO:0009295 +name: nucleoid +namespace: cellular_component +def: "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." [GOC:bm, GOC:ma, ISBN:3540076689] +xref: Wikipedia:Nucleoid +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0009296 +name: obsolete flagellum assembly +namespace: biological_process +def: "OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers." [GOC:curators, ISBN:0815316194] +synonym: "flagella assembly" EXACT [GOC:mah] +synonym: "flagella biogenesis" RELATED [] +synonym: "flagellum assembly" EXACT [] +synonym: "flagellum biogenesis" RELATED [GOC:mah] +is_obsolete: true +consider: GO:0044780 +consider: GO:0060271 + +[Term] +id: GO:0009297 +name: pilus assembly +namespace: biological_process +def: "The assembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles." [GOC:dgh, GOC:mcc2, GOC:tb] +synonym: "fimbria assembly" NARROW [] +synonym: "fimbria biogenesis" RELATED [] +synonym: "fimbriae assembly" NARROW [] +synonym: "fimbriae biogenesis" RELATED [] +synonym: "fimbrial assembly" NARROW [] +synonym: "fimbrial biogenesis" NARROW [] +synonym: "fimbrium assembly" NARROW [] +synonym: "fimbrium biogenesis" RELATED [] +synonym: "pili biosynthesis" EXACT [] +synonym: "pili biosynthetic process" EXACT [] +synonym: "pilus biogenesis" RELATED [] +synonym: "pilus biosynthesis" EXACT [] +synonym: "pilus formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030031 ! cell projection assembly +is_a: GO:0043711 ! pilus organization +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0009298 +name: GDP-mannose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-mannose anabolism" EXACT [] +synonym: "GDP-mannose biosynthesis" EXACT [] +synonym: "GDP-mannose formation" EXACT [] +synonym: "GDP-mannose synthesis" EXACT [] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0019673 ! GDP-mannose metabolic process +relationship: has_part GO:0004615 ! phosphomannomutase activity + +[Term] +id: GO:0009299 +name: mRNA transcription +namespace: biological_process +alt_id: GO:0061023 +def: "The cellular synthesis of messenger RNA (mRNA) from a DNA template." [GOC:jl] +synonym: "cellular mRNA transcription" EXACT [] +synonym: "mRNA biosynthesis" BROAD [] +synonym: "mRNA biosynthetic process" BROAD [] +synonym: "mRNA synthesis" BROAD [] +is_a: GO:0006351 ! transcription, DNA-templated +is_a: GO:0016071 ! mRNA metabolic process + +[Term] +id: GO:0009300 +name: antisense RNA transcription +namespace: biological_process +def: "The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:jl] +is_a: GO:0006351 ! transcription, DNA-templated +is_a: GO:0042868 ! antisense RNA metabolic process + +[Term] +id: GO:0009301 +name: snRNA transcription +namespace: biological_process +def: "The synthesis of small nuclear RNA (snRNA) from a DNA template." [GOC:jl, ISBN:0321000382] +is_a: GO:0098781 ! ncRNA transcription + +[Term] +id: GO:0009302 +name: snoRNA transcription +namespace: biological_process +def: "The synthesis of small nucleolar RNA (snoRNA) from a DNA template." [GOC:jl] +is_a: GO:0016074 ! snoRNA metabolic process +is_a: GO:0098781 ! ncRNA transcription + +[Term] +id: GO:0009303 +name: rRNA transcription +namespace: biological_process +def: "The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template." [GOC:jl, ISBN:0198506732] +synonym: "rRNA biosynthesis" BROAD [] +synonym: "rRNA biosynthetic process" BROAD [] +synonym: "rRNA synthesis" BROAD [] +is_a: GO:0098781 ! ncRNA transcription + +[Term] +id: GO:0009304 +name: tRNA transcription +namespace: biological_process +def: "The synthesis of transfer RNA (tRNA) from a DNA template." [GOC:jl] +synonym: "tRNA biosynthesis" BROAD [] +synonym: "tRNA biosynthetic process" BROAD [] +synonym: "tRNA synthesis" BROAD [] +is_a: GO:0098781 ! ncRNA transcription + +[Term] +id: GO:0009305 +name: protein biotinylation +namespace: biological_process +def: "The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid." [GOC:ai] +synonym: "protein amino acid biotinylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0009306 +name: protein secretion +namespace: biological_process +alt_id: GO:0045166 +alt_id: GO:0045731 +def: "The controlled release of proteins from a cell." [GOC:ai] +subset: goslim_drosophila +synonym: "glycoprotein secretion" NARROW [] +synonym: "protein secretion during cell fate commitment" NARROW [] +synonym: "protein secretion resulting in cell fate commitment" NARROW [] +is_a: GO:0002790 ! peptide secretion +is_a: GO:0015031 ! protein transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0035592 ! establishment of protein localization to extracellular region + +[Term] +id: GO:0009307 +name: DNA restriction-modification system +namespace: biological_process +def: "A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme." [GOC:jl, UniProtKB-KW:KW-0680] +synonym: "DNA restriction" BROAD [] +is_a: GO:0006304 ! DNA modification +is_a: GO:0044355 ! clearance of foreign intracellular DNA + +[Term] +id: GO:0009308 +name: amine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_pir +synonym: "amine metabolism" EXACT [] +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0009309 +name: amine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] +synonym: "amine anabolism" EXACT [] +synonym: "amine biosynthesis" EXACT [] +synonym: "amine formation" EXACT [] +synonym: "amine synthesis" EXACT [] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0009310 +name: amine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] +synonym: "amine breakdown" EXACT [] +synonym: "amine catabolism" EXACT [] +synonym: "amine degradation" EXACT [] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0009311 +name: oligosaccharide metabolic process +namespace: biological_process +alt_id: GO:0051690 +def: "The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732] +subset: goslim_yeast +synonym: "multicellular organismal oligosaccharide metabolic process" NARROW [] +synonym: "oligosaccharide metabolism" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process + +[Term] +id: GO:0009312 +name: oligosaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732] +synonym: "oligosaccharide anabolism" EXACT [] +synonym: "oligosaccharide biosynthesis" EXACT [] +synonym: "oligosaccharide formation" EXACT [] +synonym: "oligosaccharide synthesis" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0016051 ! carbohydrate biosynthetic process + +[Term] +id: GO:0009313 +name: oligosaccharide catabolic process +namespace: biological_process +alt_id: GO:0051689 +def: "The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [ISBN:0198506732] +synonym: "multicellular organismal oligosaccharide catabolic process" NARROW [] +synonym: "oligosaccharide breakdown" EXACT [] +synonym: "oligosaccharide catabolism" EXACT [] +synonym: "oligosaccharide degradation" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0016052 ! carbohydrate catabolic process + +[Term] +id: GO:0009314 +name: response to radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation] +comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength. +synonym: "response to electromagnetic radiation stimulus" EXACT [] +synonym: "response to radiation stimulus" EXACT [] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0009315 +name: obsolete drug resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "drug resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0042493 + +[Term] +id: GO:0009316 +name: 3-isopropylmalate dehydratase complex +namespace: cellular_component +def: "A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate." [BRENDA:4.2.1.33, GOC:jl, MetaCyc:3-ISOPROPYLMALISOM-CPLX, PMID:7026530] +comment: See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'. +synonym: "isopropylmalate isomerase complex" EXACT [] +xref: MetaCyc:3-ISOPROPYLMALISOM-CPLX +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0009317 +name: acetyl-CoA carboxylase complex +namespace: cellular_component +def: "A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex." [GOC:jl, GOC:mah, PMID:12121720] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "ACCase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009318 +name: exodeoxyribonuclease VII complex +namespace: cellular_component +def: "An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA." [EC:3.1.11.6] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009319 +name: cytochrome o ubiquinol oxidase complex +namespace: cellular_component +def: "A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups." [GOC:mah, MetaCyc:CYT-O-UBIOX-CPLX, PMID:11017202, PMID:3052268] +comment: See also the molecular function term 'cytochrome o ubiquinol oxidase activity ; GO:0008827'. +xref: MetaCyc:CYT-O-UBIOX-CPLX +is_a: GO:0070069 ! cytochrome complex +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0016021 ! integral component of membrane + +[Term] +id: GO:0009320 +name: phosphoribosylaminoimidazole carboxylase complex +namespace: cellular_component +def: "A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity." [GOC:mah] +comment: See also the molecular function term 'phosphoribosylaminoimidazole carboxylase activity ; GO:0004638'. +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009321 +name: alkyl hydroperoxide reductase complex +namespace: cellular_component +def: "An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides." [GOC:jl, PMID:2649484] +comment: See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'. +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009322 +name: trimethylamine-N-oxide reductase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine." [GOC:curators] +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009323 +name: ribosomal-protein-alanine N-acetyltransferase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine." [EC:2.3.1.128] +xref: EC:2.3.1.128 +xref: RHEA:43752 +is_a: GO:0031248 ! protein acetyltransferase complex + +[Term] +id: GO:0009324 +name: D-amino-acid dehydrogenase complex +namespace: cellular_component +def: "A protein complex that possesses D-amino-acid dehydrogenase activity." [GOC:mah] +comment: See also the molecular function term 'D-amino-acid oxidase activity ; GO:0003884'. +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009325 +name: nitrate reductase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor." [EC:1.7.99.4] +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009326 +name: formate dehydrogenase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2)." [EC:1.17.1.9] +xref: EC:1.17.1.9 +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009327 +name: NAD(P)+ transhydrogenase complex (AB-specific) +namespace: cellular_component +def: "A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified." [BRENDA:1.6.1.2, GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009328 +name: phenylalanine-tRNA ligase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe)." [EC:6.1.1.20] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009329 +name: acetate CoA-transferase complex +namespace: cellular_component +def: "A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA." [GOC:jl, PMID:2719476, PMID:8423010] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0009317 ! acetyl-CoA carboxylase complex + +[Term] +id: GO:0009330 +name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex +namespace: cellular_component +def: "Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity." [GOC:bhm, GOC:krc, GOC:mah, WikiPedia:Type_II_topoisomerase] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009331 +name: glycerol-3-phosphate dehydrogenase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate." [EC:1.1.5.3] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009332 +name: glutamate-tRNA ligase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu)." [EC:6.1.1.17] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009333 +name: cysteine synthase complex +namespace: cellular_component +def: "Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A." [EC:4.2.99.8, MetaCyc:CYSSYNMULTI-CPLX] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009334 +name: 3-phenylpropionate dioxygenase complex +namespace: cellular_component +def: "Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol)." [GOC:jl, MetaCyc:HCAMULTI-CPLX, PMID:9603882] +comment: See also the molecular function term '3-phenylpropionate dioxygenase activity ; GO:0008695'. +xref: MetaCyc:HCAMULTI-CPLX +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009335 +name: obsolete holo-[acyl-carrier protein] synthase complex +namespace: cellular_component +def: "OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein]." [EC:2.7.8.7] +comment: This term was made obsolete because the catalytic activity resides in a single polypeptide rather than a complex, and the complex is represented by a different GO term. +synonym: "holo-[acyl-carrier protein] synthase complex" EXACT [] +synonym: "holo-ACP synthase complex" EXACT [] +is_obsolete: true +consider: GO:0005835 + +[Term] +id: GO:0009336 +name: sulfate adenylyltransferase complex (ATP) +namespace: cellular_component +def: "An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP." [EC:2.7.7.4] +synonym: "sulphate adenylyltransferase complex (ATP)" EXACT [] +is_a: GO:1902503 ! adenylyltransferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009337 +name: sulfite reductase complex (NADPH) +namespace: cellular_component +def: "A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide." [BRENDA:1.8.1.2, GOC:jl] +comment: See also the molecular function term 'sulfite reductase (NADPH) activity ; GO:0004783'. +synonym: "sulphite reductase complex (NADPH)" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009338 +name: exodeoxyribonuclease V complex +namespace: cellular_component +def: "An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA." [EC:3.1.11.5] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009339 +name: glycolate oxidase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN)." [EC:1.1.3.15] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009340 +name: DNA topoisomerase IV complex +namespace: cellular_component +def: "A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA." [GOC:jl, PMID:7783632] +is_a: GO:0009330 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009341 +name: beta-galactosidase complex +namespace: cellular_component +def: "A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species." [BRENDA:3.2.1.2, EC:3.2.1.23, PMID:15950161] +subset: goslim_metagenomics +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0009342 +name: glutamate synthase complex (NADPH) +namespace: cellular_component +def: "A complex that possesses glutamate synthase (NADPH) activity." [EC:1.4.1.13, GOC:mah] +is_a: GO:0031026 ! glutamate synthase complex + +[Term] +id: GO:0009343 +name: biotin carboxylase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2)." [EC:6.3.4.14] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0009317 ! acetyl-CoA carboxylase complex + +[Term] +id: GO:0009344 +name: nitrite reductase complex [NAD(P)H] +namespace: cellular_component +def: "Complex that possesses nitrite reductase [NAD(P)H] activity." [GOC:mah] +comment: See also the molecular function term 'nitrite reductase [NAD(P)H] activity ; GO:0008942'. +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0009345 +name: glycine-tRNA ligase complex +namespace: cellular_component +def: "A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly)." [EC:6.1.1.14, GOC:jl, PMID:15733854] +synonym: "glycine-tRNA synthetase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009346 +name: citrate lyase complex +namespace: cellular_component +def: "Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity." [EC:4.1.3.6, MetaCyc:ACECITLY-CPLX] +subset: goslim_metagenomics +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009347 +name: aspartate carbamoyltransferase complex +namespace: cellular_component +def: "A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides." [PMID:10447693] +comment: Note that in eukaryotes, aspartate carbamoyltransferase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term. +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0009348 +name: ornithine carbamoyltransferase complex +namespace: cellular_component +def: "A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline." [EC:2.1.3.3, GOC:mah] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009349 +name: riboflavin synthase complex +namespace: cellular_component +def: "An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine." [EC:2.5.1.9] +subset: goslim_metagenomics +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0009350 +name: ethanolamine ammonia-lyase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia." [EC:4.3.1.7] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009351 +name: obsolete dihydrolipoamide S-acyltransferase complex +namespace: cellular_component +def: "OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide." [EC:2.3.1.12] +comment: This term was made obsolete because dihydrolipoamide S-acyltransferase activity resides in a single polypeptide. +synonym: "dihydrolipoamide S-acyltransferase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009352 +name: obsolete dihydrolipoyl dehydrogenase complex +namespace: cellular_component +def: "OBSOLETE. Complex that possesses dihydrolipoyl dehydrogenase activity." [GOC:mah] +comment: This term was made obsolete because the activity dihydrolipoamide dehydrogenase is held by a single protein (Lpd1 in yeast), which is one of the components of three different complexes: 2-oxoglutarate dehydrogenase, pyruvate dehydrogenase, and branch chain amino acid dehydrogenase, so dihydrolipoamide dehydrogenase is not a complex itself. +synonym: "dihydrolipoamide dehydrogenase complex" EXACT [] +synonym: "dihydrolipoyl dehydrogenase complex" EXACT [] +is_obsolete: true +consider: GO:0004148 +consider: GO:0045240 +consider: GO:0045254 + +[Term] +id: GO:0009353 +name: mitochondrial oxoglutarate dehydrogenase complex +namespace: cellular_component +def: "A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus." [GOC:mtg_sensu, MetaCyc:CPLX66-42, PMID:10848975] +comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. +is_a: GO:0005947 ! mitochondrial alpha-ketoglutarate dehydrogenase complex +is_a: GO:0045252 ! oxoglutarate dehydrogenase complex +intersection_of: GO:0045252 ! oxoglutarate dehydrogenase complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0009354 +name: obsolete dihydrolipoamide S-succinyltransferase complex +namespace: cellular_component +def: "OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex." [EC:2.3.1.61] +comment: This term was made obsolete because dihydrolipoamide S-succinyltransferase itself is not a complex, it is a component of the 2-oxoglutarate dehydrogenase complex, the activity dihydrolipoamide S-succinyltransferase is contained in a single polypeptide. +synonym: "dihydrolipoamide S-succinyltransferase complex" EXACT [] +is_obsolete: true +consider: GO:0045252 + +[Term] +id: GO:0009355 +name: DNA polymerase V complex +namespace: cellular_component +def: "A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis." [PMID:10430871, PMID:10542196] +is_a: GO:0042575 ! DNA polymerase complex + +[Term] +id: GO:0009356 +name: aminodeoxychorismate synthase complex +namespace: cellular_component +def: "A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity." [PMID:2251281, PMID:7592344] +synonym: "4-amino-4-deoxychorismate synthase complex" RELATED [] +synonym: "ADC synthase complex" EXACT [] +synonym: "p-aminobenzoate synthetase complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009357 +name: protein-N(PI)-phosphohistidine-sugar phosphotransferase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system." [EC:2.7.1.69] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +is_a: GO:1902495 ! transmembrane transporter complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009358 +name: polyphosphate kinase complex +namespace: cellular_component +def: "A protein complex that possesses polyphosphate kinase activity." [GOC:mah] +comment: See also the molecular function term 'polyphosphate kinase activity ; GO:0008976'. +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups + +[Term] +id: GO:0009359 +name: type II site-specific deoxyribonuclease complex +namespace: cellular_component +def: "A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995] +synonym: "type II restriction enzyme complex" EXACT [] +is_a: GO:1905347 ! endodeoxyribonuclease complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009360 +name: DNA polymerase III complex +namespace: cellular_component +def: "The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork." [PMID:11525729, PMID:12940977, UniProt:P06710] +synonym: "DNA polymerase III holoenzyme complex" EXACT [] +is_a: GO:0042575 ! DNA polymerase complex + +[Term] +id: GO:0009361 +name: succinate-CoA ligase complex (ADP-forming) +namespace: cellular_component +def: "A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP." [EC:6.2.1.5, GOC:jl] +synonym: "succinyl-CoA synthetase, ADP-forming" EXACT [CORUM:394] +is_a: GO:0042709 ! succinate-CoA ligase complex + +[Term] +id: GO:0009365 +name: protein histidine kinase complex +namespace: cellular_component +def: "A complex that possesses protein histidine kinase activity." [GOC:mah] +is_a: GO:1902911 ! protein kinase complex + +[Term] +id: GO:0009366 +name: enterobactin synthetase complex +namespace: cellular_component +def: "A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway." [MetaCyc:ENTMULTI-CPLX, PMID:9485415] +synonym: "enterochelin synthetase complex" EXACT [] +xref: MetaCyc:ENTMULTI-CPLX +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009367 +name: obsolete prepilin peptidase complex +namespace: cellular_component +def: "OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group." [EC:3.4.23.43] +comment: This term was made obsolete because prepilin peptidase is a single gene product, and there is no evidence that it acts as a multimer. +synonym: "prepilin peptidase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009368 +name: endopeptidase Clp complex +namespace: cellular_component +def: "A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form." [GOC:mah, PMID:11352464] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009371 +name: positive regulation of transcription by pheromones +namespace: biological_process +def: "Any process involving pheromones that activates or increases the rate of transcription." [GOC:go_curators] +synonym: "activation of transcription by pheromones" NARROW [] +synonym: "stimulation of transcription by pheromones" NARROW [] +synonym: "up regulation of transcription by pheromones" EXACT [] +synonym: "up-regulation of transcription by pheromones" EXACT [] +synonym: "upregulation of transcription by pheromones" EXACT [] +is_a: GO:0009373 ! regulation of transcription by pheromones +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated + +[Term] +id: GO:0009372 +name: quorum sensing +namespace: biological_process +alt_id: GO:0010699 +alt_id: GO:0060247 +def: "The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms." [GOC:krc, GOC:mlg, PMID:10607620, PMID:15716452, PMID:16497924, PMID:16630813, PMID:8288518] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "cell-cell signaling involved in quorum sensing" RELATED [] +synonym: "detection of cell density by secreted molecule" RELATED [] +synonym: "quorum sensing system" EXACT [] +xref: Wikipedia:Quorum_sensing +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0060245 ! detection of cell density + +[Term] +id: GO:0009373 +name: regulation of transcription by pheromones +namespace: biological_process +def: "Any process involving pheromones that modulates the frequency, rate or extent of transcription." [GOC:go_curators] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +relationship: part_of GO:0071444 ! cellular response to pheromone + +[Term] +id: GO:0009374 +name: biotin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:jl, ISBN:0198506732] +synonym: "vitamin B7 binding" EXACT [] +synonym: "vitamin H binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0033218 ! amide binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0009375 +name: ferredoxin hydrogenase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances." [EC:1.12.7.2] +synonym: "hydrogenase complex" BROAD [] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0009376 +name: HslUV protease complex +namespace: cellular_component +def: "A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer." [GOC:bhm, PMID:12670962, UniProt:P0A6H5] +synonym: "ClpYQ protease complex" EXACT [] +is_a: GO:0031597 ! cytosolic proteasome complex +is_a: GO:1904949 ! ATPase complex + +[Term] +id: GO:0009377 +name: obsolete HslUV protease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins." [GOC:mah, PMID:10368141] +comment: This term was made obsolete because it represents a gene product. +synonym: "HslUV protease activity" EXACT [] +is_obsolete: true +replaced_by: GO:0070011 + +[Term] +id: GO:0009378 +name: four-way junction helicase activity +namespace: molecular_function +alt_id: GO:1990163 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions." [GOC:al, PMID:22723423, PMID:9442895] +synonym: "ATP-dependent four-way junction DNA helicase activity" EXACT [] +synonym: "ATP-dependent four-way junction helicase activity" EXACT [] +synonym: "ATP-dependent Holliday junction helicase activity" NARROW [] +synonym: "Holliday junction helicase activity" NARROW [] +is_a: GO:0003678 ! DNA helicase activity +created_by: pr +creation_date: 2013-08-07T13:36:54Z + +[Term] +id: GO:0009379 +name: Holliday junction helicase complex +namespace: cellular_component +def: "A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA." [PMID:16935884, PMID:9442895] +is_a: GO:0033202 ! DNA helicase complex + +[Term] +id: GO:0009380 +name: excinuclease repair complex +namespace: cellular_component +def: "Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap." [GOC:mah, GOC:mlg, PMID:12145219, PMID:15192705] +synonym: "excinuclease ABC complex" EXACT [] +synonym: "UvrABC excinuclease complex" EXACT [] +is_a: GO:1905347 ! endodeoxyribonuclease complex +is_a: GO:1990391 ! DNA repair complex + +[Term] +id: GO:0009381 +name: excinuclease ABC activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind." [GOC:mah, PMID:15192705] +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0009382 +name: imidazoleglycerol-phosphate synthase complex +namespace: cellular_component +def: "Complex that possesses imidazoleglycerol-phosphate synthase activity." [GOC:mah] +comment: See also the molecular function term 'imidazoleglycerol-phosphate synthase activity ; GO:0000107'. +synonym: "imidazoleglycerol phosphate synthase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009383 +name: rRNA (cytosine-C5-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA." [GOC:imk, PMID:10026269, PMID:18786544] +synonym: "rRNA (cytosine-C5-967)-methyltransferase activity" NARROW [] +synonym: "rRNA m5C967 methyltransferase activity" NARROW [] +xref: Reactome:R-HSA-6790944 "NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447" +xref: Reactome:R-HSA-6793057 "NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841" +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0016434 ! rRNA (cytosine) methyltransferase activity + +[Term] +id: GO:0009384 +name: N-acylmannosamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate." [EC:2.7.1.60] +synonym: "acetylamidodeoxymannokinase activity" EXACT [EC:2.7.1.60] +synonym: "acetylmannosamine kinase activity" EXACT [EC:2.7.1.60] +synonym: "acylaminodeoxymannokinase activity" EXACT [EC:2.7.1.60] +synonym: "acylmannosamine kinase (phosphorylating)" EXACT [EC:2.7.1.60] +synonym: "acylmannosamine kinase activity" EXACT [EC:2.7.1.60] +synonym: "ATP:N-acetylmannosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.60] +synonym: "ATP:N-acyl-D-mannosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.60] +synonym: "N-acetylmannosamine kinase activity" EXACT [EC:2.7.1.60] +synonym: "N-acyl-D-mannosamine kinase activity" EXACT [EC:2.7.1.60] +xref: EC:2.7.1.60 +xref: MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN +xref: Reactome:R-HSA-4085028 "GNE phosphorylates ManNAc to ManNAc-6-P" +xref: Reactome:R-HSA-4088322 "Defective GNE does not phosphorylate ManNAc to ManNAc-6-P" +xref: RHEA:23832 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0009385 +name: N-acylmannosamine-6-phosphate 2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate." [MetaCyc:NANE-RXN] +synonym: "N-acylmannosamine-6-P epimerase activity" EXACT [] +xref: EC:5.1.3.9 +xref: MetaCyc:NANE-RXN +xref: RHEA:25257 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0009386 +name: translational attenuation +namespace: biological_process +def: "Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation." [PMID:15694341, PMID:15805513] +is_a: GO:0006417 ! regulation of translation + +[Term] +id: GO:0009388 +name: obsolete antisense RNA +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "antisense RNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009389 +name: dimethyl sulfoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O." [UM-BBD_reactionID:r0207] +synonym: "dimethyl sulphoxide reductase activity" EXACT [] +xref: EC:1.8.99 +xref: UM-BBD_reactionID:r0207 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0009390 +name: dimethyl sulfoxide reductase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide." [UM-BBD_enzymeID:e0188] +synonym: "dimethyl sulphoxide reductase complex" EXACT [] +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0009392 +name: N-acetyl-anhydromuramoyl-L-alanine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala." [MetaCyc:RXN0-5225] +xref: MetaCyc:RXN0-5225 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0009394 +name: 2'-deoxyribonucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar." [GOC:mah] +synonym: "2'-deoxyribonucleotide metabolism" EXACT [] +is_a: GO:0009262 ! deoxyribonucleotide metabolic process +is_a: GO:0019692 ! deoxyribose phosphate metabolic process + +[Term] +id: GO:0009395 +name: phospholipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [ISBN:0198506732] +synonym: "phospholipid breakdown" EXACT [] +synonym: "phospholipid catabolism" EXACT [] +synonym: "phospholipid degradation" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process +is_a: GO:0046434 ! organophosphate catabolic process + +[Term] +id: GO:0009396 +name: folic acid-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of folic acid and its derivatives." [GOC:ai] +synonym: "folate and derivative biosynthesis" EXACT [] +synonym: "folate and derivative biosynthetic process" EXACT [] +synonym: "folate-containing compound biosynthesis" EXACT [] +synonym: "folate-containing compound biosynthetic process" EXACT [] +synonym: "folic acid and derivative biosynthesis" EXACT [] +synonym: "folic acid and derivative biosynthetic process" EXACT [] +synonym: "folic acid-containing compound anabolism" EXACT [] +synonym: "folic acid-containing compound biosynthesis" EXACT [] +synonym: "folic acid-containing compound formation" EXACT [] +synonym: "folic acid-containing compound synthesis" EXACT [] +synonym: "vitamin B9 and derivative biosynthesis" EXACT [] +synonym: "vitamin B9 and derivative biosynthetic process" EXACT [] +synonym: "vitamin M and derivative biosynthesis" EXACT [] +synonym: "vitamin M and derivative biosynthetic process" EXACT [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0009397 +name: folic acid-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives." [GOC:ai] +synonym: "folate and derivative catabolic process" EXACT [] +synonym: "folate and derivative catabolism" EXACT [] +synonym: "folate-containing compound catabolic process" EXACT [] +synonym: "folate-containing compound catabolism" EXACT [] +synonym: "folic acid and derivative catabolic process" EXACT [] +synonym: "folic acid and derivative catabolism" EXACT [] +synonym: "folic acid-containing compound breakdown" EXACT [] +synonym: "folic acid-containing compound catabolism" EXACT [] +synonym: "folic acid-containing compound degradation" EXACT [] +synonym: "vitamin B9 and derivative catabolic process" EXACT [] +synonym: "vitamin B9 and derivative catabolism" EXACT [] +synonym: "vitamin M and derivative catabolic process" EXACT [] +synonym: "vitamin M and derivative catabolism" EXACT [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0042560 ! pteridine-containing compound catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0009398 +name: FMN biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase." [GOC:ai] +synonym: "FMN anabolism" EXACT [] +synonym: "FMN biosynthesis" EXACT [] +synonym: "FMN formation" EXACT [] +synonym: "FMN synthesis" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009156 ! ribonucleoside monophosphate biosynthetic process +is_a: GO:0009260 ! ribonucleotide biosynthetic process +is_a: GO:0042727 ! flavin-containing compound biosynthetic process +is_a: GO:0046444 ! FMN metabolic process + +[Term] +id: GO:0009399 +name: nitrogen fixation +namespace: biological_process +def: "The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide." [Wikipedia:Nitrogen_fixation] +xref: MetaCyc:N2FIX-PWY +xref: Wikipedia:Nitrogen_fixation +is_a: GO:0071941 ! nitrogen cycle metabolic process + +[Term] +id: GO:0009400 +name: obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate." [GOC:bf, GOC:mah] +comment: This term was obsoleted because it was not clearly defined. +synonym: "receptor signaling protein serine/threonine phosphatase activity" EXACT [] +synonym: "receptor signalling protein serine/threonine phosphatase activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14232 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0009401 +name: phosphoenolpyruvate-dependent sugar phosphotransferase system +namespace: biological_process +def: "The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC." [http://www.ucs.mun.ca/~n55lrb/general_pts.html] +synonym: "PTS system" NARROW [] +is_a: GO:0008643 ! carbohydrate transport + +[Term] +id: GO:0009402 +name: obsolete toxin resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "toxin resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0009636 + +[Term] +id: GO:0009403 +name: toxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:go_curators] +subset: goslim_metagenomics +synonym: "toxin anabolism" EXACT [] +synonym: "toxin biosynthesis" EXACT [] +synonym: "toxin formation" EXACT [] +synonym: "toxin synthesis" EXACT [] +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process + +[Term] +id: GO:0009404 +name: toxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:cab2] +subset: goslim_aspergillus +subset: goslim_pir +synonym: "toxin metabolism" EXACT [] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0009405 +name: pathogenesis +namespace: biological_process +def: "The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism." [GOC:go_curators] +comment: Note that this term should not be used to annotate gene products that are involved in the host response to pathogenesis. It should only be used to annotate those gene products involved in the generation of pathogenesis by the pathogen itself. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_metagenomics +synonym: "virulence" RELATED [] +is_a: GO:0044419 ! interspecies interaction between organisms + +[Term] +id: GO:0009406 +name: obsolete virulence +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a phenotype rather than a biological process. +synonym: "virulence" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0016032 + +[Term] +id: GO:0009407 +name: toxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [GOC:go_curators] +synonym: "toxin breakdown" EXACT [] +synonym: "toxin catabolism" EXACT [] +synonym: "toxin degradation" EXACT [] +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0098754 ! detoxification + +[Term] +id: GO:0009408 +name: response to heat +namespace: biological_process +alt_id: GO:0006951 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:lr] +subset: goslim_yeast +synonym: "response to heat shock" NARROW [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009266 ! response to temperature stimulus + +[Term] +id: GO:0009409 +name: response to cold +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:lr] +synonym: "freezing tolerance" RELATED [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009266 ! response to temperature stimulus + +[Term] +id: GO:0009410 +name: response to xenobiotic stimulus +namespace: biological_process +alt_id: GO:0017104 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms." [GOC:jl] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0009411 +name: response to UV +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:hb] +synonym: "response to ultraviolet light stimulus" EXACT [] +synonym: "response to ultraviolet radiation stimulus" EXACT [] +synonym: "response to UV light stimulus" EXACT [] +synonym: "response to UV radiation stimulus" EXACT [] +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0009412 +name: obsolete response to heavy metal +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:ai] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "response to heavy metal" EXACT [] +is_obsolete: true +consider: GO:0010038 + +[Term] +id: GO:0009413 +name: response to flooding +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water." [GOC:lr] +comment: Note that this term should not be confused with 'response to deep water ; GO:0030912'. Flooding refers to short-term immersion, whereas 'response to deep water ; GO:0030912' refers to standing in water throughout an organism's life cycle. +is_a: GO:0006950 ! response to stress +is_a: GO:0009415 ! response to water + +[Term] +id: GO:0009414 +name: response to water deprivation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." [GOC:lr] +synonym: "drought tolerance" RELATED [] +synonym: "response to dehydration" EXACT [] +synonym: "response to drought" EXACT [] +synonym: "response to thirst" EXACT [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009415 ! response to water + +[Term] +id: GO:0009415 +name: response to water +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." [GOC:jl] +synonym: "response to water stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009628 ! response to abiotic stimulus +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009416 +name: response to light stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089] +subset: goslim_plant +is_a: GO:0009314 ! response to radiation + +[Term] +id: GO:0009417 +name: obsolete fimbrin +namespace: cellular_component +def: "OBSOLETE. A class of proteins that are the subunit components of fimbria." [ISBN:0914826859] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "fimbrin" EXACT [] +is_obsolete: true +replaced_by: GO:0009289 + +[Term] +id: GO:0009418 +name: pilus shaft +namespace: cellular_component +def: "The long, slender, mid section of a pilus." [GOC:jl] +synonym: "fimbrial shaft" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009289 ! pilus + +[Term] +id: GO:0009419 +name: pilus tip +namespace: cellular_component +def: "The pointed extremity furthest from the cell of a pilus." [GOC:jl] +synonym: "fimbrial tip" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009289 ! pilus + +[Term] +id: GO:0009420 +name: bacterial-type flagellum filament +namespace: cellular_component +def: "The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar filament" EXACT [] +synonym: "flagellin-based flagellum filament" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009288 ! bacterial-type flagellum + +[Term] +id: GO:0009421 +name: bacterial-type flagellum filament cap +namespace: cellular_component +def: "The proteinaceous structure at the distal tip of the bacterial-type flagellar filament." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar filament cap" EXACT [] +synonym: "flagellin-based flagellum filament cap" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009420 ! bacterial-type flagellum filament + +[Term] +id: GO:0009422 +name: bacterial-type flagellum hook-filament junction +namespace: cellular_component +def: "The region of the bacterial-type flagellum where the hook and filament meet." [GOC:cilia, GOC:mah, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar hook-filament junction" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009288 ! bacterial-type flagellum + +[Term] +id: GO:0009423 +name: chorismate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds." [GOC:sm, ISBN:0198547684] +synonym: "chorismate anabolism" EXACT [] +synonym: "chorismate biosynthesis" EXACT [] +synonym: "chorismate formation" EXACT [] +synonym: "chorismate synthesis" EXACT [] +xref: MetaCyc:ARO-PWY +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0009424 +name: bacterial-type flagellum hook +namespace: cellular_component +def: "The portion of the bacterial-type flagellum that connects the filament to the basal body." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar hook" EXACT [] +synonym: "flagellin-based flagellum hook" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009288 ! bacterial-type flagellum + +[Term] +id: GO:0009425 +name: bacterial-type flagellum basal body +namespace: cellular_component +def: "One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192, PMID:24697492] +synonym: "flagellar basal body" BROAD [] +synonym: "flagellin-based flagellum basal body" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009288 ! bacterial-type flagellum + +[Term] +id: GO:0009426 +name: bacterial-type flagellum basal body, distal rod +namespace: cellular_component +def: "The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] +synonym: "flagellar basal body, distal rod" EXACT [] +synonym: "flagellin-based flagellum basal body, distal rod" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030694 ! bacterial-type flagellum basal body, rod + +[Term] +id: GO:0009427 +name: bacterial-type flagellum basal body, distal rod, L ring +namespace: cellular_component +def: "One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar basal body, distal rod, L ring" EXACT [] +synonym: "flagellin-based flagellum basal body, distal rod, L ring" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009426 ! bacterial-type flagellum basal body, distal rod + +[Term] +id: GO:0009428 +name: bacterial-type flagellum basal body, distal rod, P ring +namespace: cellular_component +def: "One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar basal body, distal rod, P ring" RELATED [] +synonym: "flagellin-based flagellum basal body, distal rod, P ring" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009426 ! bacterial-type flagellum basal body, distal rod + +[Term] +id: GO:0009429 +name: bacterial-type flagellum basal body, proximal rod +namespace: cellular_component +def: "The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] +synonym: "flagellar basal body, proximal rod" EXACT [] +synonym: "flagellin-based flagellum basal body, proximal rod" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030694 ! bacterial-type flagellum basal body, rod + +[Term] +id: GO:0009431 +name: bacterial-type flagellum basal body, MS ring +namespace: cellular_component +alt_id: GO:0009430 +def: "One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar basal body, mounting plate" BROAD [] +synonym: "flagellar basal body, MS ring" EXACT [] +synonym: "flagellin-based flagellum basal body, MS ring" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009425 ! bacterial-type flagellum basal body + +[Term] +id: GO:0009432 +name: SOS response +namespace: biological_process +def: "An error-prone process for repairing damaged microbial DNA." [GOC:jl, PMID:16000023] +xref: Wikipedia:SOS_response +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0031668 ! cellular response to extracellular stimulus +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0009433 +name: bacterial-type flagellum basal body, C ring +namespace: cellular_component +def: "Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:12624192] +synonym: "flagellar basal body, C ring" EXACT [] +synonym: "flagellin-based flagellum basal body, C ring" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009425 ! bacterial-type flagellum basal body + +[Term] +id: GO:0009435 +name: NAD biosynthetic process +namespace: biological_process +alt_id: GO:0006736 +def: "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:jl, ISBN:0618254153] +synonym: "NAD (oxidized) biosynthesis" EXACT [] +synonym: "NAD (oxidized) biosynthetic process" EXACT [] +synonym: "NAD (reduced) biosynthesis" EXACT [] +synonym: "NAD (reduced) biosynthetic process" EXACT [] +synonym: "NAD anabolism" EXACT [] +synonym: "NAD biosynthesis" EXACT [] +synonym: "NAD formation" EXACT [] +synonym: "NAD synthesis" EXACT [] +synonym: "NADH biosynthesis" EXACT [] +synonym: "NADH biosynthetic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide biosynthesis" EXACT [] +synonym: "nicotinamide adenine dinucleotide biosynthetic process" EXACT [] +synonym: "oxidized NAD biosynthesis" EXACT [] +synonym: "oxidized NAD biosynthetic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide biosynthesis" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide biosynthetic process" EXACT [] +synonym: "reduced NAD biosynthesis" EXACT [] +synonym: "reduced NAD biosynthetic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide biosynthesis" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide biosynthetic process" EXACT [] +is_a: GO:0019359 ! nicotinamide nucleotide biosynthetic process + +[Term] +id: GO:0009436 +name: glyoxylate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH." [ISBN:0198506732] +synonym: "glyoxylate breakdown" EXACT [] +synonym: "glyoxylate catabolism" EXACT [] +synonym: "glyoxylate degradation" EXACT [] +xref: MetaCyc:GLYOXDEG-PWY +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:0046487 ! glyoxylate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0009437 +name: carnitine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:jl, ISBN:0198506732] +synonym: "carnitine metabolism" EXACT [] +synonym: "vitamin Bt metabolic process" EXACT [] +synonym: "vitamin Bt metabolism" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process + +[Term] +id: GO:0009438 +name: methylglyoxal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid." [GOC:ai] +synonym: "methylglyoxal bypass" NARROW [] +synonym: "methylglyoxal metabolism" EXACT [] +synonym: "methylglyoxal pathway" NARROW [] +xref: MetaCyc:METHGLYUT-PWY +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0009439 +name: cyanate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid." [ISBN:0198506732] +synonym: "cyanate metabolism" EXACT [] +xref: MetaCyc:CYANCAT-PWY +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0009440 +name: cyanate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid." [ISBN:0198506732] +synonym: "cyanate breakdown" EXACT [] +synonym: "cyanate catabolism" EXACT [] +synonym: "cyanate degradation" EXACT [] +is_a: GO:0009439 ! cyanate metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0009441 +name: glycolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid)." [GOC:ai, ISBN:0198506732] +synonym: "glycolate metabolism" EXACT [] +xref: MetaCyc:GLYCOLATEMET-PWY +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process + +[Term] +id: GO:0009442 +name: allantoin assimilation pathway +namespace: biological_process +def: "The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP." [MetaCyc:PWY0-41] +synonym: "allantoin catabolic process via ureidoglycolate" EXACT [] +synonym: "allantoin catabolism via ureidoglycolate" EXACT [] +synonym: "allantoin degradation pathway" RELATED [] +xref: MetaCyc:PWY0-41 +is_a: GO:0000256 ! allantoin catabolic process + +[Term] +id: GO:0009443 +name: pyridoxal 5'-phosphate salvage +namespace: biological_process +def: "Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis." [GOC:jl] +synonym: "pyridoxal 5' phosphate salvage" EXACT [] +xref: MetaCyc:PLPSAL-PWY +is_a: GO:0042823 ! pyridoxal phosphate biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0009444 +name: pyruvate oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate." [MetaCyc:PYRUVOX-PWY] +xref: MetaCyc:PYRUVOX-PWY +xref: Wikipedia:Pyruvate_decarboxylation +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0009445 +name: putrescine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine." [GOC:ai] +synonym: "putrescine metabolism" EXACT [] +is_a: GO:0006595 ! polyamine metabolic process + +[Term] +id: GO:0009446 +name: putrescine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine." [GOC:go_curators, ISBN:0198506732] +synonym: "putrescine anabolism" EXACT [] +synonym: "putrescine biosynthesis" EXACT [] +synonym: "putrescine formation" EXACT [] +synonym: "putrescine synthesis" EXACT [] +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:0009445 ! putrescine metabolic process + +[Term] +id: GO:0009447 +name: putrescine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine." [GOC:ai] +synonym: "putrescine breakdown" EXACT [] +synonym: "putrescine catabolism" EXACT [] +synonym: "putrescine degradation" EXACT [] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:0009445 ! putrescine metabolic process + +[Term] +id: GO:0009448 +name: gamma-aminobutyric acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [ISBN:0198506732] +comment: See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'. +synonym: "4-aminobutanoate metabolic process" EXACT [] +synonym: "4-aminobutanoate metabolism" EXACT [] +synonym: "4-aminobutyrate metabolic process" EXACT [] +synonym: "4-aminobutyrate metabolism" EXACT [] +synonym: "GABA metabolic process" EXACT [] +synonym: "GABA metabolism" EXACT [] +synonym: "gamma-aminobutyric acid metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process + +[Term] +id: GO:0009449 +name: gamma-aminobutyric acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [GOC:ai] +comment: See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'. +synonym: "4-aminobutanoate biosynthesis" EXACT [] +synonym: "4-aminobutanoate biosynthetic process" EXACT [] +synonym: "4-aminobutyrate biosynthesis" EXACT [] +synonym: "4-aminobutyrate biosynthetic process" EXACT [] +synonym: "GABA biosynthesis" EXACT [] +synonym: "GABA biosynthetic process" EXACT [] +synonym: "gamma-aminobutyric acid anabolism" EXACT [] +synonym: "gamma-aminobutyric acid biosynthesis" EXACT [] +synonym: "gamma-aminobutyric acid formation" EXACT [] +synonym: "gamma-aminobutyric acid synthesis" EXACT [] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0009448 ! gamma-aminobutyric acid metabolic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0009450 +name: gamma-aminobutyric acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." [GOC:ai] +comment: See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'. +synonym: "4-aminobutanoate catabolic process" EXACT [] +synonym: "4-aminobutanoate catabolism" EXACT [] +synonym: "4-aminobutyrate catabolic process" EXACT [] +synonym: "4-aminobutyrate catabolism" EXACT [] +synonym: "GABA catabolic process" EXACT [] +synonym: "GABA catabolism" EXACT [] +synonym: "gamma-aminobutyric acid breakdown" EXACT [] +synonym: "gamma-aminobutyric acid catabolism" EXACT [] +synonym: "gamma-aminobutyric acid degradation" EXACT [] +xref: MetaCyc:4AMINOBUTMETAB-PWY +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0009448 ! gamma-aminobutyric acid metabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0009451 +name: RNA modification +namespace: biological_process +alt_id: GO:0016547 +def: "The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically." [GOC:go_curators, ISBN:1555811337] +comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. +subset: goslim_yeast +synonym: "RNA editing" NARROW [GOC:hjd] +xref: Wikipedia:RNA_editing +is_a: GO:0016070 ! RNA metabolic process +is_a: GO:0043412 ! macromolecule modification + +[Term] +id: GO:0009452 +name: 7-methylguanosine RNA capping +namespace: biological_process +def: "The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript." [GOC:vw, PMID:9266685] +synonym: "m(7)G RNA capping" EXACT [GOC:bf, GOC:krc, GOC:mah] +synonym: "RNA capping" BROAD [GOC:krc, GOC:mah] +is_a: GO:0036260 ! RNA capping + +[Term] +id: GO:0009453 +name: energy taxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates." [GOC:jl, PMID:11029423] +synonym: "energytaxis" EXACT [] +synonym: "taxis in response to energy source" EXACT [] +is_a: GO:0042330 ! taxis + +[Term] +id: GO:0009454 +name: aerotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to environmental oxygen." [GOC:jl, ISBN:0192801023] +synonym: "taxis in response to atmospheric oxygen" EXACT [] +is_a: GO:0006935 ! chemotaxis +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0009455 +name: redox taxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to redox potential." [GOC:jl, PMID:11029423] +synonym: "redoxtaxis" EXACT [] +synonym: "taxis in response to redox potential" EXACT [] +synonym: "taxis in response to redox stimulus" EXACT [] +is_a: GO:0006935 ! chemotaxis +is_a: GO:0009453 ! energy taxis +is_a: GO:0051775 ! response to redox state + +[Term] +id: GO:0009457 +name: obsolete flavodoxin +namespace: molecular_function +def: "OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide." [GOC:kd] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "flavodoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009458 +name: obsolete cytochrome +namespace: molecular_function +def: "OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom." [PMID:1655423] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome" EXACT [] +is_obsolete: true +consider: GO:0045153 +consider: GO:0045154 +consider: GO:0045155 +consider: GO:0045156 +consider: GO:0045157 +consider: GO:0045158 + +[Term] +id: GO:0009459 +name: obsolete cytochrome a +namespace: molecular_function +def: "OBSOLETE. A cytochrome containing heme a." [GOC:kd] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome a" EXACT [] +is_obsolete: true +replaced_by: GO:0045154 + +[Term] +id: GO:0009460 +name: obsolete cytochrome b +namespace: molecular_function +def: "OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b)." [GOC:kd] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome b" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009461 +name: obsolete cytochrome c +namespace: molecular_function +def: "OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues." [GOC:kd] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome c" EXACT [] +is_obsolete: true +replaced_by: GO:0045155 + +[Term] +id: GO:0009462 +name: obsolete cytochrome d +namespace: molecular_function +def: "OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes." [GOC:kd, PMID:1655423] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome d" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009463 +name: obsolete cytochrome b/b6 +namespace: molecular_function +def: "OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis." [ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome b/b6" EXACT [] +is_obsolete: true +replaced_by: GO:0045158 + +[Term] +id: GO:0009464 +name: obsolete cytochrome b5 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome b5" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009465 +name: obsolete soluble cytochrome b562 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "soluble cytochrome b562" EXACT [] +is_obsolete: true +replaced_by: GO:0045153 + +[Term] +id: GO:0009466 +name: obsolete class I cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class I cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009467 +name: obsolete monoheme class I cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "monoheme class I cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009468 +name: obsolete diheme class I cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "diheme class I cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009469 +name: obsolete class II cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class II cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009470 +name: obsolete class IIa cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class IIa cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009471 +name: obsolete class III cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class III cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009472 +name: obsolete cytochrome c3 (tetraheme) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome c3 (tetraheme)" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009473 +name: obsolete cytochrome c7 (triheme) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome c7 (triheme)" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009474 +name: obsolete nonaheme cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "nonaheme cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009475 +name: obsolete high-molecular-weight cytochrome c (hexadecaheme) +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "high-molecular-weight cytochrome c (hexadecaheme)" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009476 +name: obsolete class IV cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class IV cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009477 +name: obsolete cytochrome c1 +namespace: molecular_function +def: "OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c." [PMID:1655423] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome c1" EXACT [] +is_obsolete: true +replaced_by: GO:0045153 + +[Term] +id: GO:0009478 +name: obsolete cytochrome c554 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome c554" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009479 +name: obsolete cytochrome f +namespace: molecular_function +def: "OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin." [PMID:1655423] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome f" EXACT [] +is_obsolete: true +replaced_by: GO:0045158 + +[Term] +id: GO:0009480 +name: obsolete class IIb cytochrome c +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "class IIb cytochrome c" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0009481 +name: obsolete aa3-type cytochrome c oxidase +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] +comment: This term was made obsolete because it describes a class of gene products rather than a molecular function. +synonym: "aa3-type cytochrome c oxidase" EXACT [] +is_obsolete: true +replaced_by: GO:0004129 + +[Term] +id: GO:0009482 +name: obsolete ba3-type cytochrome c oxidase +namespace: molecular_function +alt_id: GO:0009484 +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] +comment: This term was made obsolete because it describes a class of gene products rather than a molecular function. +synonym: "ba3-type cytochrome c oxidase" EXACT [] +is_obsolete: true +replaced_by: GO:0004129 + +[Term] +id: GO:0009483 +name: obsolete caa3-type cytochrome c oxidase +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] +comment: This term was made obsolete because it describes a class of gene products rather than a molecular function. +synonym: "caa3-type cytochrome c oxidase" EXACT [] +is_obsolete: true +replaced_by: GO:0004129 + +[Term] +id: GO:0009485 +name: obsolete cbb3-type cytochrome c oxidase +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] +comment: This term was made obsolete because it describes a class of gene products rather than a molecular function. +synonym: "cbb3-type cytochrome c oxidase" EXACT [] +is_obsolete: true +replaced_by: GO:0004129 + +[Term] +id: GO:0009486 +name: cytochrome bo3 ubiquinol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]." [MetaCyc:RXN0-5268] +xref: EC:1.10.3 +xref: MetaCyc:RXN0-5268 +is_a: GO:0015002 ! heme-copper terminal oxidase activity + +[Term] +id: GO:0009487 +name: obsolete glutaredoxin +namespace: molecular_function +def: "OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase." [GOC:kd] +comment: This term was made obsolete because it represents a gene product. +synonym: "glutaredoxin" EXACT [] +is_obsolete: true +consider: GO:0003756 +consider: GO:0015036 +consider: GO:0015038 + +[Term] +id: GO:0009488 +name: obsolete amicyanin +namespace: molecular_function +def: "OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c." [PMID:1655423] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "amicyanin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009489 +name: obsolete rubredoxin +namespace: molecular_function +def: "OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues." [GOC:kd] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "rubredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009490 +name: obsolete mononuclear iron electron carrier +namespace: molecular_function +def: "OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "mononuclear iron electron carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009491 +name: obsolete redox-active disulfide bond electron carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "redox-active disulfide bond electron carrier" EXACT [] +synonym: "redox-active disulphide bond electron carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009492 +name: obsolete 2Fe-2S electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "2Fe-2S electron transfer carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009493 +name: obsolete adrenodoxin-type ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "adrenodoxin-type ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009494 +name: obsolete chloroplast-type ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "chloroplast-type ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009495 +name: obsolete thioredoxin-like 2Fe-2S ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "thioredoxin-like 2Fe-2S ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009496 +name: plastoquinol--plastocyanin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane." [EC:1.10.9.1] +synonym: "cytochrome b6-f complex activity" RELATED [EC:1.10.9.1] +synonym: "cytochrome b6/f complex activity" RELATED [EC:1.10.9.1] +synonym: "cytochrome b6f" NARROW [EC:1.10.99.1] +synonym: "cytochrome b6f complex activity" RELATED [EC:1.10.9.1] +synonym: "plastoquinol-plastocyanin reductase activity" EXACT [EC:1.10.9.1] +synonym: "plastoquinol/plastocyanin oxidoreductase activity" EXACT [EC:1.10.99.1] +synonym: "plastoquinol:oxidized-plastocyanin oxidoreductase activity" EXACT [EC:1.10.99.1] +xref: EC:1.10.9.1 +xref: KEGG_REACTION:R03817 +xref: MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN +is_a: GO:0052880 ! oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor + +[Term] +id: GO:0009497 +name: obsolete 3Fe-4S/4Fe-4S electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "3Fe-4S/4Fe-4S electron transfer carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009498 +name: obsolete bacterial-type ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "bacterial-type ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009499 +name: obsolete monocluster bacterial-type ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "monocluster bacterial-type ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009500 +name: obsolete dicluster bacterial-type ferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "dicluster bacterial-type ferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0009501 +name: amyloplast +namespace: cellular_component +def: "A plastid whose main function is to synthesize and store starch." [ISBN:0140514031] +xref: Wikipedia:Amyloplast +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009502 +name: obsolete photosynthetic electron transport chain +namespace: cellular_component +def: "OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen)." [GOC:mtg_electron_transport, ISBN:0140514031] +comment: This term was made obsolete because it represents a process. +synonym: "photosynthetic electron transport chain" EXACT [] +is_obsolete: true +consider: GO:0009767 + +[Term] +id: GO:0009503 +name: thylakoid light-harvesting complex +namespace: cellular_component +def: "A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0198547684] +is_a: GO:0030076 ! light-harvesting complex +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +intersection_of: GO:0030076 ! light-harvesting complex +intersection_of: part_of GO:0009535 ! chloroplast thylakoid membrane + +[Term] +id: GO:0009504 +name: cell plate +namespace: cellular_component +def: "The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells." [ISBN:0198547684] +xref: Wikipedia:Cell_plate +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009505 +name: plant-type cell wall +namespace: cellular_component +def: "A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances." [ISBN:0471245208] +synonym: "cellulose and pectin-containing cell wall" EXACT [] +synonym: "plant cell wall" NARROW [] +is_a: GO:0005618 ! cell wall + +[Term] +id: GO:0009506 +name: plasmodesma +namespace: cellular_component +def: "A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [PMID:29880547] +synonym: "plasmodesmata" EXACT [] +xref: Wikipedia:Plasmodesma +is_a: GO:0005911 ! cell-cell junction +relationship: part_of GO:0055044 ! symplast + +[Term] +id: GO:0009507 +name: chloroplast +namespace: cellular_component +def: "A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." [ISBN:0471245208] +subset: goslim_plant +xref: Wikipedia:Chloroplast +is_a: GO:0009536 ! plastid +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0009508 +name: plastid chromosome +namespace: cellular_component +def: "A circular DNA molecule containing plastid encoded genes." [ISBN:0943088399] +is_a: GO:0000229 ! cytoplasmic chromosome +intersection_of: GO:0005694 ! chromosome +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0042646 ! plastid nucleoid + +[Term] +id: GO:0009509 +name: chromoplast +namespace: cellular_component +def: "A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments." [ISBN:0471245208] +xref: Wikipedia:Chromoplast +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009510 +name: plasmodesmatal desmotubule +namespace: cellular_component +alt_id: GO:0009572 +def: "A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell." [PMID:29880547] +synonym: "desmotubule central rod" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0009506 ! plasmodesma + +[Term] +id: GO:0009511 +name: plasmodesmatal endoplasmic reticulum +namespace: cellular_component +def: "Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells." [GOC:ai, PMID:29880547] +synonym: "plasmodesmatal ER" EXACT [] +is_a: GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0009510 ! plasmodesmatal desmotubule + +[Term] +id: GO:0009512 +name: cytochrome b6f complex +namespace: cellular_component +def: "Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species." [ISBN:0943088399, PMID:16228398, PMID:16352458] +synonym: "cyt b(6)f complex" EXACT [] +synonym: "cyt b6-f complex" EXACT [] +synonym: "cyt b6/f complex" EXACT [] +synonym: "cyt b6f complex" EXACT [] +synonym: "cytochrome b(6)f complex" EXACT [] +synonym: "cytochrome b6-f complex" EXACT [] +synonym: "cytochrome b6/f complex" EXACT [] +xref: Wikipedia:Cytochrome_b6f_complex +is_a: GO:0070069 ! cytochrome complex +relationship: part_of GO:0009579 ! thylakoid + +[Term] +id: GO:0009513 +name: etioplast +namespace: cellular_component +def: "A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions." [ISBN:0943088399] +xref: Wikipedia:Etioplast +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009514 +name: glyoxysome +namespace: cellular_component +def: "A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds." [GOC:dhl, ISBN:0140514031] +xref: Wikipedia:Glyoxysome +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0009515 +name: granal stacked thylakoid +namespace: cellular_component +def: "Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II." [GOC:lr] +synonym: "chloroplast stacked thylakoid" EXACT [] +is_a: GO:0009534 ! chloroplast thylakoid +intersection_of: GO:0009534 ! chloroplast thylakoid +intersection_of: part_of GO:0009542 ! granum +relationship: part_of GO:0009542 ! granum + +[Term] +id: GO:0009516 +name: leucoplast +namespace: cellular_component +def: "A colorless plastid involved in the synthesis of monoterpenes." [ISBN:0943088399] +xref: Wikipedia:Leucoplast +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009517 +name: PSII associated light-harvesting complex II +namespace: cellular_component +def: "Protein-pigment complex associated with photosystem II." [GOC:lr, ISBN:0582227089] +synonym: "LHCII" EXACT [] +is_a: GO:0009503 ! thylakoid light-harvesting complex + +[Term] +id: GO:0009518 +name: PSI associated light-harvesting complex I +namespace: cellular_component +def: "Protein-pigment complex associated with photosystem I." [GOC:lr] +synonym: "LHCI" EXACT [] +is_a: GO:0009503 ! thylakoid light-harvesting complex + +[Term] +id: GO:0009519 +name: middle lamella +namespace: cellular_component +def: "Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells." [ISBN:0471245208] +xref: Wikipedia:Middle_lamella +is_a: GO:0031012 ! extracellular matrix + +[Term] +id: GO:0009521 +name: photosystem +namespace: cellular_component +alt_id: GO:0030090 +def: "A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949] +subset: goslim_pir +synonym: "reaction center" NARROW [] +synonym: "reaction centre" NARROW [] +xref: Wikipedia:Photosystem +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0034357 ! photosynthetic membrane + +[Term] +id: GO:0009522 +name: photosystem I +namespace: cellular_component +def: "A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation)." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949] +is_a: GO:0009521 ! photosystem + +[Term] +id: GO:0009523 +name: photosystem II +namespace: cellular_component +def: "A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center." [GOC:ds, GOC:mah, ISBN:0943088399, PMID:9821949] +xref: Wikipedia:Photosystem_II +is_a: GO:0009521 ! photosystem + +[Term] +id: GO:0009524 +name: phragmoplast +namespace: cellular_component +def: "Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules." [ISBN:0471245208] +xref: Wikipedia:Phragmoplast +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009525 +name: phragmosome +namespace: cellular_component +def: "A flattened membranous vesicle containing cell wall components." [ISBN:0943088399] +xref: Wikipedia:Phragmosome +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0009526 +name: plastid envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:jy] +is_a: GO:0031967 ! organelle envelope +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0009527 +name: plastid outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope." [GOC:lr] +is_a: GO:0031968 ! organelle outer membrane +is_a: GO:0042170 ! plastid membrane + +[Term] +id: GO:0009528 +name: plastid inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma." [GOC:lr] +is_a: GO:0019866 ! organelle inner membrane +is_a: GO:0042170 ! plastid membrane + +[Term] +id: GO:0009529 +name: plastid intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of the plastid envelope." [GOC:lr] +synonym: "plastid envelope lumen" EXACT [] +is_a: GO:0031970 ! organelle envelope lumen +relationship: part_of GO:0009526 ! plastid envelope + +[Term] +id: GO:0009530 +name: primary cell wall +namespace: cellular_component +def: "A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present." [GOC:jid, PMID:9442872] +is_a: GO:0009505 ! plant-type cell wall + +[Term] +id: GO:0009531 +name: secondary cell wall +namespace: cellular_component +def: "A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin." [GOC:jid, ISBN:0943088399] +xref: Wikipedia:Secondary_cell_wall +is_a: GO:0009505 ! plant-type cell wall + +[Term] +id: GO:0009532 +name: plastid stroma +namespace: cellular_component +def: "The proteinaceous ground substance of plastids." [ISBN:0943088399] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0009533 +name: chloroplast stromal thylakoid +namespace: cellular_component +def: "Unstacked thylakoids that connect the grana stacks through the stroma." [ISBN:0943088399] +is_a: GO:0009534 ! chloroplast thylakoid +intersection_of: GO:0009534 ! chloroplast thylakoid +intersection_of: part_of GO:0009570 ! chloroplast stroma +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0009534 +name: chloroplast thylakoid +namespace: cellular_component +def: "Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0943088399] +is_a: GO:0031976 ! plastid thylakoid +intersection_of: GO:0009579 ! thylakoid +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0009535 +name: chloroplast thylakoid membrane +namespace: cellular_component +def: "The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +is_a: GO:0055035 ! plastid thylakoid membrane +relationship: part_of GO:0009534 ! chloroplast thylakoid + +[Term] +id: GO:0009536 +name: plastid +namespace: cellular_component +def: "Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." [GOC:jl, ISBN:0198547684] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +xref: Wikipedia:Plastid +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0009537 +name: proplastid +namespace: cellular_component +def: "The precursor of other plastids." [ISBN:0943088399] +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009538 +name: photosystem I reaction center +namespace: cellular_component +def: "A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin." [GOC:kd, ISBN:0943088399] +synonym: "photosystem I reaction centre" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009522 ! photosystem I + +[Term] +id: GO:0009539 +name: photosystem II reaction center +namespace: cellular_component +def: "An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone." [GOC:kd, ISBN:0943088399] +synonym: "photosystem II reaction centre" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009523 ! photosystem II + +[Term] +id: GO:0009540 +name: zeaxanthin epoxidase [overall] activity +namespace: molecular_function +def: "Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O; and antheraxanthin + NAD(P)H + H+ + O2 = violaxanthin + NAD(P)+ + H2O." [EC:1.14.13.90] +comment: This is a process composed of two reactions represented by the terms 'GO:0052662 : zeaxanthin epoxidase activity' and 'GO:0052663 : antheraxanthin epoxidase activity'. +synonym: "zea-epoxidase activity" RELATED [EC:1.14.13.90] +synonym: "zeaxanthin,NAD(P)H:oxygen oxidoreductase activity" RELATED [EC:1.14.13.90] +xref: EC:1.14.13.90 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0009541 +name: etioplast prolamellar body +namespace: cellular_component +def: "A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast." [ISBN:0140514031] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009513 ! etioplast + +[Term] +id: GO:0009542 +name: granum +namespace: cellular_component +def: "Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis." [ISBN:0140514031] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0009543 +name: chloroplast thylakoid lumen +namespace: cellular_component +def: "The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0943088399] +is_a: GO:0031978 ! plastid thylakoid lumen +relationship: part_of GO:0009534 ! chloroplast thylakoid + +[Term] +id: GO:0009544 +name: chloroplast ATP synthase complex +namespace: cellular_component +def: "The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts." [ISBN:0198547684] +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex + +[Term] +id: GO:0009545 +name: elaioplast +namespace: cellular_component +def: "A leucoplast in which oil is stored." [ISBN:0140514031] +xref: Wikipedia:Elaioplast +is_a: GO:0009516 ! leucoplast + +[Term] +id: GO:0009546 +name: plasmodesmatal cytoplasmic sleeve +namespace: cellular_component +def: "The space between the plasma membrane and the desmotubule of a plasmodesma." [PMID:29880547] +synonym: "plasmodesmatal cytoplasmic annulus" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0009506 ! plasmodesma + +[Term] +id: GO:0009547 +name: plastid ribosome +namespace: cellular_component +def: "A ribosome contained within a plastid." [GOC:tair_curators] +is_a: GO:0000313 ! organellar ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009532 ! plastid stroma + +[Term] +id: GO:0009548 +name: plasmodesmatal plasma membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a plasmodesma." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0009506 ! plasmodesma + +[Term] +id: GO:0009549 +name: cellulose microfibril +namespace: cellular_component +def: "A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell." [GOC:jid, ISBN:0943088399] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009505 ! plant-type cell wall + +[Term] +id: GO:0009550 +name: primary plasmodesma +namespace: cellular_component +def: "A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis." [PMID:15012255] +synonym: "simple plasmodesma" EXACT [] +is_a: GO:0009506 ! plasmodesma + +[Term] +id: GO:0009551 +name: secondary plasmodesma +namespace: cellular_component +def: "A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata." [PMID:15012255] +is_a: GO:0009506 ! plasmodesma + +[Term] +id: GO:0009553 +name: embryo sac development +namespace: biological_process +alt_id: GO:0048230 +def: "The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate." [GOC:mtg_plant, GOC:tb] +synonym: "female gametophyte development" EXACT [] +is_a: GO:0048229 ! gametophyte development + +[Term] +id: GO:0009554 +name: megasporogenesis +namespace: biological_process +def: "The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus." [GOC:mtg_plant, GOC:tb] +synonym: "megaspore development" EXACT [] +synonym: "megaspore mother cell meiosis" EXACT [] +synonym: "meiosis of the megasporocyte" EXACT [] +synonym: "meiotic division of the megasporocyte" EXACT [] +is_a: GO:0048236 ! plant-type sporogenesis +relationship: part_of GO:0009553 ! embryo sac development + +[Term] +id: GO:0009555 +name: pollen development +namespace: biological_process +alt_id: GO:0009564 +alt_id: GO:0048231 +def: "The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates." [GOC:mtg_plant, GOC:mtg_sensu, GOC:tb] +synonym: "formation of generative and vegetative cells" EXACT [] +synonym: "male gametophyte development" EXACT [] +synonym: "male gametophyte formation" EXACT [] +synonym: "microgametophyte development" EXACT [] +synonym: "pollen grain formation" EXACT [] +is_a: GO:0048229 ! gametophyte development + +[Term] +id: GO:0009556 +name: microsporogenesis +namespace: biological_process +def: "The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores." [GOC:mtg_plant, GOC:tb] +synonym: "microspore development" EXACT systematic_synonym [] +is_a: GO:0048236 ! plant-type sporogenesis +relationship: part_of GO:0009555 ! pollen development + +[Term] +id: GO:0009557 +name: antipodal cell differentiation +namespace: biological_process +def: "The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell." [GOC:jid, GOC:mtg_plant] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009558 +name: embryo sac cellularization +namespace: biological_process +alt_id: GO:0009797 +def: "The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana." [GOC:jid, GOC:mtg_plant, GOC:mtg_sensu, ISBN:047186840X] +synonym: "cellularization of the embryo sac" EXACT [] +synonym: "female gametophyte cellularization" EXACT [] +synonym: "megagametophyte cellularization" EXACT [] +is_a: GO:0007349 ! cellularization +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009559 +name: embryo sac central cell differentiation +namespace: biological_process +def: "The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell." [GOC:jid, GOC:mtg_plant] +synonym: "embryo sac endosperm mother cell differentiation" EXACT [] +synonym: "female gametophyte central cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009560 +name: embryo sac egg cell differentiation +namespace: biological_process +alt_id: GO:0048233 +def: "The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana." [GOC:jid, GOC:mtg_plant, GOC:mtg_sensu] +synonym: "female gamete generation" BROAD [] +synonym: "female gametophyte egg cell differentiation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007292 ! female gamete generation +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009561 +name: megagametogenesis +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center." [GOC:jl, GOC:mtg_plant] +synonym: "embryo sac development from the megaspore" EXACT systematic_synonym [] +synonym: "megagametophyte nucleus division" EXACT [] +xref: Wikipedia:Megagametogenesis +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0009553 ! embryo sac development + +[Term] +id: GO:0009562 +name: embryo sac nuclear migration +namespace: biological_process +def: "The directed movement of an embryo sac nucleus to the pole or center of the cell." [GOC:jl, GOC:mtg_plant] +synonym: "embryo sac nucleus migration" EXACT [] +synonym: "female gametophyte nuclear migration" EXACT [] +synonym: "female gametophyte nucleus migration" EXACT [] +synonym: "megagametophyte nuclear migration" EXACT [] +synonym: "megagametophyte nucleus migration" EXACT [] +is_a: GO:0007097 ! nuclear migration +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009563 +name: synergid differentiation +namespace: biological_process +def: "The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell." [GOC:jid] +synonym: "synergid cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0009566 +name: fertilization +namespace: biological_process +def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732] +synonym: "syngamy" EXACT [] +xref: Wikipedia:Fertilisation +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0019953 ! sexual reproduction + +[Term] +id: GO:0009567 +name: double fertilization forming a zygote and endosperm +namespace: biological_process +def: "Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tb] +synonym: "double fertilization" EXACT [] +is_a: GO:0009566 ! fertilization + +[Term] +id: GO:0009568 +name: amyloplast starch grain +namespace: cellular_component +def: "Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, PMID:11217978] +synonym: "amyloplast starch granule" EXACT [] +is_a: GO:0043036 ! starch grain +intersection_of: GO:0043036 ! starch grain +intersection_of: part_of GO:0009501 ! amyloplast +relationship: part_of GO:0009501 ! amyloplast + +[Term] +id: GO:0009569 +name: chloroplast starch grain +namespace: cellular_component +def: "Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, ISBN:0198506732] +synonym: "chloroplast starch granule" EXACT [] +is_a: GO:0043036 ! starch grain +intersection_of: GO:0043036 ! starch grain +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0009570 +name: chloroplast stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis." [ISBN:0198547684] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0009571 +name: proplastid stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of a proplastid." [GOC:jl] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009537 ! proplastid + +[Term] +id: GO:0009573 +name: chloroplast ribulose bisphosphate carboxylase complex +namespace: cellular_component +def: "A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana." [GOC:mlg, GOC:mtg_sensu] +synonym: "chloroplast RubisCO complex" EXACT [] +is_a: GO:0048492 ! ribulose bisphosphate carboxylase complex +intersection_of: GO:0048492 ! ribulose bisphosphate carboxylase complex +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0009574 +name: preprophase band +namespace: cellular_component +def: "A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs." [ISBN:0198506732] +xref: Wikipedia:Preprophase_band +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0009575 +name: chromoplast stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material." [GOC:jl] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009509 ! chromoplast + +[Term] +id: GO:0009576 +name: leucoplast stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of a leucoplast." [GOC:mah] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009516 ! leucoplast + +[Term] +id: GO:0009577 +name: elaioplast stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of an elaioplast." [GOC:mah] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009545 ! elaioplast + +[Term] +id: GO:0009578 +name: etioplast stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA." [GOC:jl] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009513 ! etioplast + +[Term] +id: GO:0009579 +name: thylakoid +namespace: cellular_component +def: "A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation." [GOC:ds, GOC:mtg_sensu, ISBN:0198506732] +comment: A thylakoid is not considered an organelle, but some thylakoids are part of organelles. +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "photosynthetic membrane" RELATED [] +xref: Wikipedia:Thylakoid +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0009580 +name: obsolete thylakoid (sensu Bacteria) +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific children exist. +synonym: "thylakoid (sensu Bacteria)" EXACT [] +is_obsolete: true +consider: GO:0030075 +consider: GO:0042716 + +[Term] +id: GO:0009581 +name: detection of external stimulus +namespace: biological_process +def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb] +synonym: "perception of external stimulus" RELATED [] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0009582 +name: detection of abiotic stimulus +namespace: biological_process +def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb] +synonym: "perception of abiotic stimulus" RELATED [] +is_a: GO:0009628 ! response to abiotic stimulus +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0009583 +name: detection of light stimulus +namespace: biological_process +def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators] +synonym: "detection of light" EXACT [] +synonym: "perception of light" RELATED [] +is_a: GO:0009416 ! response to light stimulus +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009582 ! detection of abiotic stimulus + +[Term] +id: GO:0009584 +name: detection of visible light +namespace: biological_process +def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] +synonym: "perception of visible light" RELATED [] +is_a: GO:0009583 ! detection of light stimulus + +[Term] +id: GO:0009585 +name: red, far-red light phototransduction +namespace: biological_process +def: "The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm." [GOC:mah] +synonym: "phytochrome signaling pathway" BROAD [] +synonym: "red-sensitive opsin" RELATED [] +is_a: GO:0007602 ! phototransduction +relationship: part_of GO:0010017 ! red or far-red light signaling pathway + +[Term] +id: GO:0009587 +name: obsolete phototrophin mediated phototransduction +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +synonym: "phototrophin mediated phototransduction" EXACT [] +is_obsolete: true +replaced_by: GO:0007602 + +[Term] +id: GO:0009588 +name: UV-A, blue light phototransduction +namespace: biological_process +def: "The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm." [GOC:mah] +synonym: "blue-sensitive opsin" RELATED [] +synonym: "short-wave-sensitive opsin" RELATED [] +synonym: "violet-sensitive opsin" RELATED [] +is_a: GO:0007602 ! phototransduction + +[Term] +id: GO:0009589 +name: detection of UV +namespace: biological_process +def: "The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:dos, GOC:go_curators, GOC:hb, ISBN:0198506732] +synonym: "detection of ultraviolet light stimulus" EXACT [] +synonym: "detection of ultraviolet radiation stimulus" EXACT [] +synonym: "detection of UV light stimulus" EXACT [] +synonym: "detection of UV radiation stimulus" EXACT [] +synonym: "perception of UV" RELATED [] +is_a: GO:0009411 ! response to UV +is_a: GO:0009583 ! detection of light stimulus + +[Term] +id: GO:0009590 +name: detection of gravity +namespace: biological_process +def: "The series of events in which a gravitational stimulus is received and converted into a molecular signal." [GOC:dos, GOC:hb] +synonym: "perception of gravity" RELATED [] +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009582 ! detection of abiotic stimulus +is_a: GO:0009629 ! response to gravity + +[Term] +id: GO:0009591 +name: obsolete perception of mechanical stimulus +namespace: biological_process +alt_id: GO:0007609 +def: "OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal." [GOC:hb] +comment: This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage. +synonym: "perception of mechanical stimulus" EXACT [] +is_obsolete: true +consider: GO:0050954 + +[Term] +id: GO:0009593 +name: detection of chemical stimulus +namespace: biological_process +def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl] +synonym: "chemoperception" EXACT [] +synonym: "chemoreception" RELATED [] +synonym: "detection of chemical substance" EXACT [] +synonym: "perception of chemical stimulus" RELATED [] +synonym: "perception of chemical substance" RELATED [] +is_a: GO:0051606 ! detection of stimulus +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0009594 +name: detection of nutrient +namespace: biological_process +def: "The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal." [GOC:jl] +synonym: "detection of nutrients" EXACT [] +synonym: "nutrient sensing" RELATED [] +synonym: "perception of nutrients" RELATED [] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0009595 +name: detection of biotic stimulus +namespace: biological_process +alt_id: GO:0009596 +def: "The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal." [GOC:hb] +synonym: "perception of biotic stimulus" RELATED [] +is_a: GO:0009607 ! response to biotic stimulus +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0009597 +name: detection of virus +namespace: biological_process +def: "The series of events in which a stimulus from a virus is received and converted into a molecular signal." [GOC:hb] +comment: GO:0009597 is not a child term of 'detection of symbiont ; GO:0009602' to allow annotation of a virus responding to another (often competing) virus. +synonym: "perception of virus" RELATED [] +is_a: GO:0009615 ! response to virus + +[Term] +id: GO:0009600 +name: detection of nematode +namespace: biological_process +def: "The series of events in which a stimulus from a nematode is received and converted into a molecular signal." [GOC:hb] +synonym: "perception of nematode" RELATED [] +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0009601 +name: detection of insect +namespace: biological_process +def: "The series of events in which a stimulus from an insect is received and converted into a molecular signal." [GOC:hb] +synonym: "perception of insect" RELATED [] +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0009602 +name: detection of symbiont +namespace: biological_process +alt_id: GO:0051855 +def: "The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:hb, ISBN:0198506732] +synonym: "perception of symbiont" RELATED [] +synonym: "recognition of symbiont" EXACT [] +is_a: GO:0009608 ! response to symbiont +is_a: GO:0051702 ! interaction with symbiont +is_a: GO:0098543 ! detection of other organism +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17977 xsd:anyURI + +[Term] +id: GO:0009603 +name: detection of symbiotic fungus +namespace: biological_process +def: "The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal." [GOC:hb, ISBN:0198506732] +synonym: "detection of symbiotic fungi" EXACT [] +synonym: "perception of symbiotic fungi" RELATED [] +synonym: "perception of symbiotic fungus" RELATED [] +is_a: GO:0009602 ! detection of symbiont +is_a: GO:0009610 ! response to symbiotic fungus +is_a: GO:0016046 ! detection of fungus + +[Term] +id: GO:0009604 +name: detection of symbiotic bacterium +namespace: biological_process +def: "The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal." [GOC:hb, ISBN:0198506732] +synonym: "detection of symbiotic bacteria" EXACT [] +synonym: "perception of symbiotic bacteria" RELATED [] +synonym: "perception of symbiotic bacterium" RELATED [] +is_a: GO:0009602 ! detection of symbiont +is_a: GO:0009609 ! response to symbiotic bacterium +is_a: GO:0016045 ! detection of bacterium + +[Term] +id: GO:0009605 +name: response to external stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_drosophila +subset: goslim_plant +synonym: "response to environmental stimulus" EXACT [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0009606 +name: tropism +namespace: biological_process +def: "The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it." [GOC:curators, ISBN:0877795088] +subset: goslim_plant +xref: Wikipedia:Tropism +is_a: GO:0009605 ! response to external stimulus + +[Term] +id: GO:0009607 +name: response to biotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_metagenomics +subset: goslim_plant +synonym: "response to biotic stress" NARROW [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0009608 +name: response to symbiont +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:hb, ISBN:0198506732] +synonym: "response of host to symbiont" RELATED [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009609 +name: response to symbiotic bacterium +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism." [GOC:hb, ISBN:0198506732] +synonym: "response to symbiotic bacteria" EXACT [] +is_a: GO:0009608 ! response to symbiont +is_a: GO:0009617 ! response to bacterium + +[Term] +id: GO:0009610 +name: response to symbiotic fungus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism." [GOC:hb, ISBN:0198506732] +synonym: "response to symbiotic fungi" EXACT [] +is_a: GO:0009608 ! response to symbiont +is_a: GO:0009620 ! response to fungus + +[Term] +id: GO:0009611 +name: response to wounding +namespace: biological_process +alt_id: GO:0002245 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." [GOC:go_curators] +synonym: "physiological response to wounding" EXACT [] +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0009612 +name: response to mechanical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus." [GOC:hb] +synonym: "chemi-mechanical coupling" RELATED [] +synonym: "mechanical stimulus response" EXACT [] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0009614 +name: obsolete disease resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "disease resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0051707 + +[Term] +id: GO:0009615 +name: response to virus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus." [GOC:hb] +synonym: "response to viruses" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009616 +name: virus induced gene silencing +namespace: biological_process +def: "Specific posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes. This silencing is triggered by viral infection, and occurs through a specific decrease in the level of mRNA of both host and viral genes." [GOC:jl] +comment: Virus-induced gene silencing (VIGS) is a RNA-mediated post-transcriptional gene silencing mechanism that protects plants against foreign gene invasion. +synonym: "VIGS" EXACT [] +synonym: "virus-induced gene silencing" EXACT [] +is_a: GO:0045087 ! innate immune response +is_a: GO:0051607 ! defense response to virus +is_a: GO:0052018 ! modulation by symbiont of RNA levels in host +is_a: GO:0098586 ! cellular response to virus + +[Term] +id: GO:0009617 +name: response to bacterium +namespace: biological_process +alt_id: GO:0009618 +alt_id: GO:0009680 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb] +synonym: "response to bacteria" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009619 +name: obsolete resistance to pathogenic bacteria +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "resistance to pathogenic bacteria" EXACT [] +is_obsolete: true +replaced_by: GO:0009617 + +[Term] +id: GO:0009620 +name: response to fungus +namespace: biological_process +alt_id: GO:0009621 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb] +synonym: "response to fungi" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009622 +name: obsolete resistance to pathogenic fungi +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "resistance to pathogenic fungi" EXACT [] +is_obsolete: true +replaced_by: GO:0009620 + +[Term] +id: GO:0009624 +name: response to nematode +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode." [GOC:hb] +synonym: "response to nematodes" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009625 +name: response to insect +namespace: biological_process +alt_id: GO:0043019 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect." [GOC:hb] +synonym: "response to insects" EXACT [] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0009626 +name: plant-type hypersensitive response +namespace: biological_process +def: "The rapid, localized death of plant cells in response to invasion by a pathogen." [ISBN:0582227089] +comment: Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider the biological process term 'modulation by symbiont of host defense-related programmed cell death ; GO:0034053'. +synonym: "HR" BROAD [] +synonym: "HR-PCD" EXACT [] +synonym: "plant hypersensitive response" EXACT [] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0034050 ! host programmed cell death induced by symbiont +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0009627 +name: systemic acquired resistance +namespace: biological_process +def: "The salicylic acid mediated response to a pathogen which confers broad spectrum resistance." [GOC:lr, ISBN:0521436125] +synonym: "salicylic acid-dependent systemic resistance" EXACT [] +xref: Wikipedia:Systemic_acquired_resistance +is_a: GO:0009814 ! defense response, incompatible interaction + +[Term] +id: GO:0009628 +name: response to abiotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_metagenomics +subset: goslim_plant +synonym: "response to abiotic stress" NARROW [] +is_a: GO:0050896 ! response to stimulus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16572 xsd:anyURI + +[Term] +id: GO:0009629 +name: response to gravity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus." [GOC:hb] +synonym: "response to gravitational stimulus" EXACT [] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0009630 +name: gravitropism +namespace: biological_process +def: "The orientation of plant parts under the stimulation of gravity." [ISBN:0198547684] +synonym: "geotropism" EXACT [] +xref: Wikipedia:Gravitropism +is_a: GO:0009606 ! tropism +is_a: GO:0009629 ! response to gravity + +[Term] +id: GO:0009631 +name: cold acclimation +namespace: biological_process +def: "Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures." [GOC:syr] +is_a: GO:0009409 ! response to cold + +[Term] +id: GO:0009632 +name: obsolete freezing tolerance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process. +synonym: "freezing tolerance" EXACT [] +is_obsolete: true +consider: GO:0009409 + +[Term] +id: GO:0009633 +name: obsolete drought tolerance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process. +synonym: "drought tolerance" EXACT [] +is_obsolete: true +consider: GO:0009414 +consider: GO:0009819 + +[Term] +id: GO:0009634 +name: obsolete heavy metal sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "heavy metal sensitivity/resistance" EXACT [] +is_obsolete: true +consider: GO:0010038 + +[Term] +id: GO:0009635 +name: response to herbicide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants." [GOC:curators] +synonym: "herbicide susceptibility/resistance" RELATED [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009636 ! response to toxic substance + +[Term] +id: GO:0009636 +name: response to toxic substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr] +subset: goslim_chembl +synonym: "detoxification response" NARROW [] +synonym: "toxin resistance" RELATED [] +synonym: "toxin susceptibility/resistance" RELATED [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0009637 +name: response to blue light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm." [GOC:ai, GOC:mtg_far_red] +synonym: "response to blue light stimulus" EXACT [] +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0009638 +name: phototropism +namespace: biological_process +def: "The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it." [GOC:jl, GOC:mtg_far_red, PMID:16870491] +xref: Wikipedia:Phototropism +is_a: GO:0009606 ! tropism +is_a: GO:0009637 ! response to blue light + +[Term] +id: GO:0009639 +name: response to red or far red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:ai, GOC:mtg_far_red] +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0009640 +name: photomorphogenesis +namespace: biological_process +def: "The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis." [GOC:lr] +synonym: "plant development in response to light" EXACT systematic_synonym [] +xref: Wikipedia:Photomorphogenesis +is_a: GO:0009639 ! response to red or far red light +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0009641 +name: shade avoidance +namespace: biological_process +def: "Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome." [Wikipedia:Shade_avoidance] +xref: Wikipedia:Shade_avoidance +is_a: GO:0009639 ! response to red or far red light + +[Term] +id: GO:0009642 +name: response to light intensity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus." [GOC:go_curators] +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0009643 +name: photosynthetic acclimation +namespace: biological_process +def: "A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light." [GOC:mah, PMID:11069694] +synonym: "light acclimatization" EXACT [PMID:11069694] +synonym: "photoacclimation" EXACT [GOC:tb] +is_a: GO:0009642 ! response to light intensity + +[Term] +id: GO:0009644 +name: response to high light intensity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus." [GOC:go_curators] +is_a: GO:0009642 ! response to light intensity + +[Term] +id: GO:0009645 +name: response to low light intensity stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2." [GOC:go_curators, GOC:mtg_far_red] +is_a: GO:0009642 ! response to light intensity + +[Term] +id: GO:0009646 +name: response to absence of light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli." [GOC:go_curators] +synonym: "response to darkness" RELATED [] +is_a: GO:0009642 ! response to light intensity + +[Term] +id: GO:0009647 +name: skotomorphogenesis +namespace: biological_process +def: "The control of plant growth, development, and differentiation in response to growth in darkness." [http://www.plantphys.net/article.php?ch=t&id=63, PMID:15012288] +synonym: "etiolation" RELATED [] +is_a: GO:0009646 ! response to absence of light +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0009648 +name: photoperiodism +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "response to day length" EXACT [] +synonym: "response to night length" EXACT [] +synonym: "response to photoperiod" EXACT [] +xref: Wikipedia:Photoperiodism +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0009649 +name: entrainment of circadian clock +namespace: biological_process +def: "The synchronization of a circadian rhythm to environmental time cues such as light." [GOC:jid] +synonym: "regulation of circadian rhythm phase" RELATED [] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0042752 ! regulation of circadian rhythm + +[Term] +id: GO:0009650 +name: UV protection +namespace: biological_process +def: "Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV." [GOC:jl, GOC:ml] +synonym: "ultraviolet protection" EXACT [] +synonym: "ultraviolet resistance" RELATED [] +synonym: "ultraviolet tolerance" RELATED [] +synonym: "UV resistance" RELATED [] +synonym: "UV tolerance" RELATED [] +is_a: GO:0009411 ! response to UV + +[Term] +id: GO:0009651 +name: response to salt stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:jl] +synonym: "response to ionic osmotic stress" EXACT [] +synonym: "salinity response" EXACT [] +is_a: GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0009652 +name: thigmotropism +namespace: biological_process +def: "The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it." [GOC:jl, PMID:16153165] +xref: Wikipedia:Thigmotropism +is_a: GO:0009606 ! tropism +is_a: GO:0009612 ! response to mechanical stimulus + +[Term] +id: GO:0009653 +name: anatomical structure morphogenesis +namespace: biological_process +def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125] +synonym: "anatomical structure organization" EXACT [] +synonym: "embryogenesis and morphogenesis" BROAD [] +synonym: "morphogenesis" EXACT [] +xref: Wikipedia:Morphogenesis +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0048856 ! anatomical structure development + +[Term] +id: GO:0009654 +name: photosystem II oxygen evolving complex +namespace: cellular_component +def: "A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ)." [GOC:cjm, InterPro:IPR002683] +synonym: "OEC (PSII) complex" EXACT [GOC:cjm] +synonym: "oxygen evolving complex" EXACT [GOC:cjm] +xref: Wikipedia:Oxygen_evolving_complex +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0009523 ! photosystem II +relationship: part_of GO:0042651 ! thylakoid membrane + +[Term] +id: GO:0009655 +name: PSII associated light-harvesting complex II, core complex +namespace: cellular_component +def: "The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center." [GOC:lr] +synonym: "PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex" NARROW [] +synonym: "PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex" NARROW [] +synonym: "PSII associated light-harvesting complex II, core complex, LHCIId subcomplex" NARROW [] +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +relationship: part_of GO:0009517 ! PSII associated light-harvesting complex II + +[Term] +id: GO:0009656 +name: PSII associated light-harvesting complex II, peripheral complex +namespace: cellular_component +def: "Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light." [GOC:lr] +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +relationship: part_of GO:0009517 ! PSII associated light-harvesting complex II + +[Term] +id: GO:0009657 +name: plastid organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid." [GOC:mah] +subset: goslim_pir +synonym: "plastid organisation" EXACT [] +synonym: "plastid organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0009658 +name: chloroplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast." [GOC:jid] +synonym: "chloroplast organisation" EXACT [] +synonym: "chloroplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0009659 +name: leucoplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes." [GOC:jid] +synonym: "leucoplast organisation" EXACT [] +synonym: "leucoplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0009660 +name: amyloplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch." [GOC:jid] +synonym: "amyloplast organisation" EXACT [] +synonym: "amyloplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0009661 +name: chromoplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments." [GOC:jid] +synonym: "chromoplast organisation" EXACT [] +synonym: "chromoplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0009662 +name: etioplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions." [GOC:jid] +synonym: "etioplast organisation" EXACT [] +synonym: "etioplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0009663 +name: plasmodesma organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [GOC:mah, PMID:29880547] +synonym: "plasmodesma organisation" EXACT [] +synonym: "plasmodesma organization and biogenesis" RELATED [] +synonym: "plasmodesmata organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045216 ! cell-cell junction organization + +[Term] +id: GO:0009664 +name: plant-type cell wall organization +namespace: biological_process +def: "A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana." [GOC:jid, GOC:mtg_sensu] +synonym: "cell wall organization and biogenesis" NARROW [] +synonym: "cellulose and pectin-containing cell wall organization and biogenesis" RELATED [GOC:mah] +synonym: "plant-type cell wall organisation" EXACT [] +synonym: "plant-type cell wall organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071555 ! cell wall organization +is_a: GO:0071669 ! plant-type cell wall organization or biogenesis + +[Term] +id: GO:0009665 +name: plastid inheritance +namespace: biological_process +def: "The partitioning of plastids between daughter cells at cell division." [GOC:mah] +is_a: GO:0009657 ! plastid organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0009666 +name: plastid outer membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "plastid outer membrane organisation" EXACT [] +synonym: "plastid outer membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009668 ! plastid membrane organization + +[Term] +id: GO:0009667 +name: plastid inner membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "plastid inner membrane organisation" EXACT [] +synonym: "plastid inner membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009668 ! plastid membrane organization + +[Term] +id: GO:0009668 +name: plastid membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "plastid membrane organisation" EXACT [] +synonym: "plastid membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0009657 ! plastid organization + +[Term] +id: GO:0009669 +name: sucrose:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in)." [GOC:jy, TC:2.A.2.-.-, TC:2.A.2.4.1] +synonym: "sucrose permease activity" RELATED [] +synonym: "sucrose:monovalent cation symporter activity" EXACT [] +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0008515 ! sucrose transmembrane transporter activity + +[Term] +id: GO:0009670 +name: triose-phosphate:phosphate antiporter activity +namespace: molecular_function +alt_id: GO:0015122 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out)." [GOC:bf, GOC:jl, GOC:mtg_transport, ISBN:0815340729, TC:2.A.7.-.-] +synonym: "dihydroxyacetone phosphate:phosphate antiporter activity" EXACT [] +synonym: "TPT" RELATED [] +synonym: "triose phosphate antiporter" EXACT [] +synonym: "triose phosphate translocator" EXACT [] +is_a: GO:0015315 ! organophosphate:inorganic phosphate antiporter activity +is_a: GO:0071917 ! triose-phosphate transmembrane transporter activity + +[Term] +id: GO:0009671 +name: nitrate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in)." [GOC:mah, PMID:10066586, PMID:1990981] +synonym: "nitrate(chlorate):hydrogen symporter activity" EXACT [] +synonym: "nitrate(chlorate):proton symporter activity" EXACT [] +synonym: "nitrate:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015296 ! anion:cation symporter activity +is_a: GO:0015513 ! high-affinity secondary active nitrite transmembrane transporter activity + +[Term] +id: GO:0009672 +name: auxin:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in)." [PMID:8688077] +synonym: "auxin:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0080161 ! auxin transmembrane transporter activity + +[Term] +id: GO:0009673 +name: low-affinity phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.20.-.-] +synonym: "low affinity phosphate transmembrane transporter activity" EXACT [] +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity + +[Term] +id: GO:0009674 +name: potassium:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in)." [TC:2.A.38.3.1] +synonym: "high affinity potassium transporter" RELATED [] +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0009675 +name: high-affinity sulfate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mah] +synonym: "high affinity sulfate:hydrogen symporter activity" EXACT [] +synonym: "high affinity sulfate:proton symporter activity" EXACT [] +synonym: "high affinity sulphate:hydrogen symporter activity" EXACT [] +is_a: GO:0008512 ! sulfate:proton symporter activity + +[Term] +id: GO:0009676 +name: low-affinity sulfate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mah, PMID:7568135] +synonym: "low affinity sulfate:hydrogen symporter activity" EXACT [] +synonym: "low affinity sulfate:proton symporter activity" EXACT [] +synonym: "low affinity sulphate:hydrogen symporter activity" EXACT [] +is_a: GO:0008512 ! sulfate:proton symporter activity + +[Term] +id: GO:0009677 +name: double fertilization forming two zygotes +namespace: biological_process +def: "Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis." [GOC:mtg_sensu, GOC:tb] +is_a: GO:0009566 ! fertilization + +[Term] +id: GO:0009678 +name: pyrophosphate hydrolysis-driven proton transmembrane transporter activity +namespace: molecular_function +def: "Enables the transmembrane transport of one proton (H+), driven by the hydrolysis of pyrophosphate, and generating a proton motive force." [GOC:mtg_transport, ISBN:0815340729, Wikipedia:Proton-pumping_pyrophosphatase] +synonym: "diphosphate hydrolysis-driven proton transmembrane transporter activity" EXACT [] +synonym: "H(+)-exporting diphosphatase" RELATED [EC:7.1.3.1] +synonym: "hydrogen-translocating pyrophosphatase activity" EXACT [EC:7.1.3.1] +synonym: "PP(i) hydrolysis-driven proton transmembrane transporter activity" EXACT [] +synonym: "proton-pumping diphosphatase" RELATED [EC:7.1.3.1] +synonym: "proton-pumping pyrophosphatase" RELATED [EC:7.1.3.1] +synonym: "proton-translocating pyrophosphatase activity" EXACT [] +xref: EC:7.1.3.1 +xref: MetaCyc:TRANS-RXN-370 +xref: RHEA:13973 +xref: TC:3.A.10 +is_a: GO:0015078 ! proton transmembrane transporter activity +is_a: GO:0015399 ! primary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +relationship: has_part GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0009679 +name: hexose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in)." [TC:2.A.1.-.-] +synonym: "hexose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015149 ! hexose transmembrane transporter activity + +[Term] +id: GO:0009682 +name: induced systemic resistance +namespace: biological_process +def: "A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling." [PMID:10234273] +is_a: GO:0042742 ! defense response to bacterium +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0009683 +name: indoleacetic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants." [GOC:mah] +synonym: "IAA metabolic process" EXACT [] +synonym: "indole acetic acid metabolic process" EXACT [] +synonym: "indole acetic acid metabolism" EXACT [] +synonym: "indoleacetic acid metabolism" EXACT [] +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process + +[Term] +id: GO:0009684 +name: indoleacetic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants." [ISBN:0387969845] +synonym: "IAA biosynthetic process" EXACT [] +synonym: "indole acetic acid biosynthesis" EXACT [] +synonym: "indole acetic acid biosynthetic process" EXACT [] +synonym: "indole-3-acetate biosynthesis" EXACT [] +synonym: "indole-3-acetate biosynthetic process" EXACT [] +synonym: "indole-acetic acid biosynthesis" EXACT [] +synonym: "indole-acetic acid biosynthetic process" RELATED [] +synonym: "indoleacetic acid anabolism" EXACT [] +synonym: "indoleacetic acid biosynthesis" EXACT [] +synonym: "indoleacetic acid formation" EXACT [] +synonym: "indoleacetic acid synthesis" EXACT [] +is_a: GO:0009683 ! indoleacetic acid metabolic process +is_a: GO:0009851 ! auxin biosynthetic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0009685 +name: gibberellin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators." [ISBN:0387969845] +synonym: "gibberellic acid metabolic process" NARROW [] +synonym: "gibberellic acid metabolism" NARROW [] +synonym: "gibberellin metabolism" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0009686 +name: gibberellin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators." [ISBN:0387969845] +synonym: "gibberellic acid anabolism" NARROW [] +synonym: "gibberellic acid biosynthesis" NARROW [] +synonym: "gibberellic acid biosynthetic process" NARROW [] +synonym: "gibberellic acid formation" NARROW [] +synonym: "gibberellic acid synthesis" NARROW [] +synonym: "gibberellin biosynthesis" EXACT [] +xref: MetaCyc:PWY-5035 +xref: MetaCyc:PWY-5036 +xref: MetaCyc:PWY-5052 +xref: MetaCyc:PWY-5070 +is_a: GO:0009685 ! gibberellin metabolic process +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0009687 +name: abscisic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid." [ISBN:0387969845] +synonym: "abscisic acid metabolism" EXACT [] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043288 ! apocarotenoid metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process + +[Term] +id: GO:0009688 +name: abscisic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid." [ISBN:0387969845] +synonym: "abscisic acid anabolism" EXACT [] +synonym: "abscisic acid biosynthesis" EXACT [] +synonym: "abscisic acid formation" EXACT [] +synonym: "abscisic acid synthesis" EXACT [] +xref: MetaCyc:PWY-695 +is_a: GO:0009687 ! abscisic acid metabolic process +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0043289 ! apocarotenoid biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process + +[Term] +id: GO:0009689 +name: induction of phytoalexin biosynthetic process +namespace: biological_process +def: "The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection." [ISBN:0943088399] +synonym: "induction of phytoalexin anabolism" EXACT [] +synonym: "induction of phytoalexin biosynthesis" EXACT [] +synonym: "induction of phytoalexin formation" EXACT [] +synonym: "induction of phytoalexin synthesis" EXACT [] +is_a: GO:0009814 ! defense response, incompatible interaction +is_a: GO:0052322 ! positive regulation of phytoalexin biosynthetic process + +[Term] +id: GO:0009690 +name: cytokinin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators." [ISBN:0387969845] +subset: goslim_chembl +synonym: "cytokinin metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0009691 +name: cytokinin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators." [ISBN:0387969845] +synonym: "cytokinin anabolism" EXACT [] +synonym: "cytokinin biosynthesis" EXACT [] +synonym: "cytokinin formation" EXACT [] +synonym: "cytokinin synthesis" EXACT [] +is_a: GO:0009690 ! cytokinin metabolic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0009692 +name: ethylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator." [ISBN:0387969845] +synonym: "ethene metabolic process" EXACT [] +synonym: "ethene metabolism" EXACT [] +synonym: "ethylene metabolism" EXACT [] +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0043449 ! cellular alkene metabolic process + +[Term] +id: GO:0009693 +name: ethylene biosynthetic process +namespace: biological_process +alt_id: GO:0042456 +def: "The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator." [ISBN:0387969845] +synonym: "ethene biosynthesis" EXACT [] +synonym: "ethene biosynthesis from L-methionine" EXACT [] +synonym: "ethene biosynthetic process" EXACT [] +synonym: "ethene biosynthetic process from L-methionine" EXACT [] +synonym: "ethylene anabolism" EXACT [] +synonym: "ethylene biosynthesis" EXACT [] +synonym: "ethylene biosynthesis from L-methionine" EXACT [] +synonym: "ethylene biosynthetic process from L-methionine" EXACT [] +synonym: "ethylene formation" EXACT [] +synonym: "ethylene synthesis" EXACT [] +xref: MetaCyc:ETHYL-PWY +is_a: GO:0009692 ! ethylene metabolic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0043450 ! alkene biosynthetic process + +[Term] +id: GO:0009694 +name: jasmonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid." [ISBN:0387969845] +synonym: "jasmonic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0009695 +name: jasmonic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative." [ISBN:0387969845] +synonym: "jasmonic acid anabolism" EXACT [] +synonym: "jasmonic acid biosynthesis" EXACT [] +synonym: "jasmonic acid formation" EXACT [] +synonym: "jasmonic acid synthesis" EXACT [] +xref: MetaCyc:PWY-735 +is_a: GO:0009694 ! jasmonic acid metabolic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0009696 +name: salicylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid." [ISBN:0943088399] +synonym: "salicylic acid metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0009697 +name: salicylic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid." [ISBN:0943088399] +synonym: "salicylate biosynthetic process" EXACT [] +synonym: "salicylic acid anabolism" EXACT [] +synonym: "salicylic acid biosynthesis" EXACT [] +synonym: "salicylic acid formation" EXACT [] +synonym: "salicylic acid synthesis" EXACT [] +xref: MetaCyc:PWY-981 +is_a: GO:0009696 ! salicylic acid metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0009698 +name: phenylpropanoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid." [GOC:jl] +synonym: "phenylpropanoid metabolism" EXACT [] +xref: MetaCyc:PWY1F-467 +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0009699 +name: phenylpropanoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid." [GOC:jl] +synonym: "phenylpropanoid anabolism" EXACT [] +synonym: "phenylpropanoid biosynthesis" EXACT [] +synonym: "phenylpropanoid formation" EXACT [] +synonym: "phenylpropanoid synthesis" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0009700 +name: indole phytoalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response." [GOC:sm, ISBN:0198547684] +synonym: "indole phytoalexin anabolism" EXACT [] +synonym: "indole phytoalexin biosynthesis" EXACT [] +synonym: "indole phytoalexin formation" EXACT [] +synonym: "indole phytoalexin synthesis" EXACT [] +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0046217 ! indole phytoalexin metabolic process +is_a: GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0009701 +name: isoflavonoid phytoalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection." [GOC:ai] +synonym: "isoflavonoid phytoalexin anabolism" EXACT [] +synonym: "isoflavonoid phytoalexin biosynthesis" EXACT [] +synonym: "isoflavonoid phytoalexin formation" EXACT [] +synonym: "isoflavonoid phytoalexin synthesis" EXACT [] +is_a: GO:0009717 ! isoflavonoid biosynthetic process +is_a: GO:0046289 ! isoflavonoid phytoalexin metabolic process +is_a: GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0009702 +name: L-arabinokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.46, RHEA:20153] +synonym: "ATP:L-arabinose 1-phosphotransferase activity" EXACT [] +synonym: "L-arabinokinase (phosphorylating)" EXACT [EC:2.7.1.46] +xref: EC:2.7.1.46 +xref: KEGG_REACTION:R01754 +xref: MetaCyc:L-ARABINOKINASE-RXN +xref: RHEA:20153 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0009703 +name: nitrate reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+." [EC:1.7.1.1] +comment: Note that this function was formerly EC:1.6.6.1. +synonym: "assimilatory NADH: nitrate reductase activity" EXACT [EC:1.7.1.1] +synonym: "assimilatory NADH:nitrate reductase activity" EXACT [EC:1.7.1.1] +synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.1.1] +synonym: "NADH-dependent nitrate reductase activity" EXACT [EC:1.7.1.1] +synonym: "NADH-nitrate reductase activity" EXACT [EC:1.7.1.1] +synonym: "NADH:nitrate oxidoreductase activity" EXACT [EC:1.7.1.1] +synonym: "NADH:nitrate reductase activity" EXACT [] +synonym: "nitrate reductase (NADH(2)) activity" EXACT [EC:1.7.1.1] +synonym: "nitrate reductase (NADH2)" EXACT [EC:1.7.1.1] +synonym: "nitrite:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.1] +xref: EC:1.7.1.1 +xref: MetaCyc:NITRATE-REDUCTASE-NADH-RXN +xref: RHEA:17913 +is_a: GO:0050463 ! nitrate reductase [NAD(P)H] activity + +[Term] +id: GO:0009704 +name: de-etiolation +namespace: biological_process +def: "The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll." [GOC:lr] +is_a: GO:0009416 ! response to light stimulus +relationship: part_of GO:0009640 ! photomorphogenesis + +[Term] +id: GO:0009705 +name: plant-type vacuole membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana." [GOC:mtg_sensu, ISBN:0471245208] +synonym: "membrane of vacuole with cell cycle-independent morphology" EXACT [] +synonym: "tonoplast" EXACT [] +synonym: "vacuolar membrane" BROAD [] +is_a: GO:0005774 ! vacuolar membrane +relationship: part_of GO:0000325 ! plant-type vacuole + +[Term] +id: GO:0009706 +name: chloroplast inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma." [GOC:tb] +synonym: "chloroplast inner envelope" EXACT [] +is_a: GO:0009528 ! plastid inner membrane +is_a: GO:0031969 ! chloroplast membrane + +[Term] +id: GO:0009707 +name: chloroplast outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope." [GOC:tb] +synonym: "chloroplast outer envelope" EXACT [] +is_a: GO:0009527 ! plastid outer membrane +is_a: GO:0031969 ! chloroplast membrane + +[Term] +id: GO:0009708 +name: benzyl isoquinoline alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings." [GOC:ai, ISBN:0198506732] +synonym: "benzyl isoquinoline alkaloid anabolism" EXACT [] +synonym: "benzyl isoquinoline alkaloid biosynthesis" EXACT [] +synonym: "benzyl isoquinoline alkaloid formation" EXACT [] +synonym: "benzyl isoquinoline alkaloid synthesis" EXACT [] +is_a: GO:0033075 ! isoquinoline alkaloid biosynthetic process +is_a: GO:0046445 ! benzyl isoquinoline alkaloid metabolic process + +[Term] +id: GO:0009709 +name: terpenoid indole alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)." [GOC:ai, http://rycomusa.com/aspp2000/public/P29/0525.html] +synonym: "terpenoid indole alkaloid anabolism" EXACT [] +synonym: "terpenoid indole alkaloid biosynthesis" EXACT [] +synonym: "terpenoid indole alkaloid formation" EXACT [] +synonym: "terpenoid indole alkaloid synthesis" EXACT [] +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:0046447 ! terpenoid indole alkaloid metabolic process + +[Term] +id: GO:0009710 +name: tropane alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system." [GOC:ai, ISBN:0198506732] +synonym: "tropane alkaloid anabolism" EXACT [] +synonym: "tropane alkaloid biosynthesis" EXACT [] +synonym: "tropane alkaloid formation" EXACT [] +synonym: "tropane alkaloid synthesis" EXACT [] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046448 ! tropane alkaloid metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0009711 +name: purine alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure." [GOC:ai] +synonym: "purine alkaloid anabolism" EXACT [] +synonym: "purine alkaloid biosynthesis" EXACT [] +synonym: "purine alkaloid formation" EXACT [] +synonym: "purine alkaloid synthesis" EXACT [] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0046446 ! purine alkaloid metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0009712 +name: catechol-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684] +synonym: "catechol metabolic process" RELATED [] +synonym: "catechol metabolism" RELATED [] +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0009713 +name: catechol-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] +synonym: "catechol anabolism" RELATED [] +synonym: "catechol biosynthesis" RELATED [] +synonym: "catechol biosynthetic process" RELATED [] +synonym: "catechol formation" RELATED [] +synonym: "catechol synthesis" RELATED [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0009714 +name: chalcone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives." [ISBN:0198506732] +synonym: "chalcone metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0009715 +name: chalcone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives." [GOC:go_curators] +synonym: "chalcone anabolism" EXACT [] +synonym: "chalcone biosynthesis" EXACT [] +synonym: "chalcone formation" EXACT [] +synonym: "chalcone synthesis" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009714 ! chalcone metabolic process +is_a: GO:0042181 ! ketone biosynthetic process + +[Term] +id: GO:0009716 +name: flavonoid phytoalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection." [ISBN:0198506732] +synonym: "flavonoid phytoalexin anabolism" EXACT [] +synonym: "flavonoid phytoalexin biosynthesis" EXACT [] +synonym: "flavonoid phytoalexin formation" EXACT [] +synonym: "flavonoid phytoalexin synthesis" EXACT [] +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:0046285 ! flavonoid phytoalexin metabolic process +is_a: GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0009717 +name: isoflavonoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids." [GOC:ai] +synonym: "isoflavonoid anabolism" EXACT [] +synonym: "isoflavonoid biosynthesis" EXACT [] +synonym: "isoflavonoid formation" EXACT [] +synonym: "isoflavonoid synthesis" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046287 ! isoflavonoid metabolic process + +[Term] +id: GO:0009718 +name: anthocyanin-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins." [GOC:ai] +synonym: "anthocyanin anabolism" EXACT [] +synonym: "anthocyanin biosynthesis" EXACT [] +synonym: "anthocyanin biosynthetic process" EXACT [] +synonym: "anthocyanin formation" EXACT [] +synonym: "anthocyanin synthesis" EXACT [] +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0046283 ! anthocyanin-containing compound metabolic process + +[Term] +id: GO:0009719 +name: response to endogenous stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_plant +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0009720 +name: detection of hormone stimulus +namespace: biological_process +def: "The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of hormone stimulus" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0009725 ! response to hormone +is_a: GO:0009726 ! detection of endogenous stimulus + +[Term] +id: GO:0009721 +name: detection of auxin stimulus +namespace: biological_process +def: "The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of auxin stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009733 ! response to auxin + +[Term] +id: GO:0009722 +name: detection of cytokinin stimulus +namespace: biological_process +def: "The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of cytokinin stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009735 ! response to cytokinin + +[Term] +id: GO:0009723 +name: response to ethylene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus." [GOC:jl] +synonym: "response to ethene stimulus" EXACT [] +synonym: "response to ethylene stimulus" EXACT [] +is_a: GO:0009725 ! response to hormone + +[Term] +id: GO:0009724 +name: detection of abscisic acid stimulus +namespace: biological_process +def: "The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of abscisic acid stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009737 ! response to abscisic acid + +[Term] +id: GO:0009725 +name: response to hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl] +synonym: "growth regulator" RELATED [] +synonym: "response to hormone stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0009726 +name: detection of endogenous stimulus +namespace: biological_process +def: "The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of endogenous stimulus" RELATED [] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0009727 +name: detection of ethylene stimulus +namespace: biological_process +def: "The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "detection of ethene stimulus" EXACT [] +synonym: "perception of ethene stimulus" RELATED [] +synonym: "perception of ethylene stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009723 ! response to ethylene + +[Term] +id: GO:0009728 +name: detection of gibberellic acid stimulus +namespace: biological_process +def: "The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of gibberellic acid stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009739 ! response to gibberellin + +[Term] +id: GO:0009729 +name: detection of brassinosteroid stimulus +namespace: biological_process +def: "The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of brassinosteroid stimulus" RELATED [] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0009741 ! response to brassinosteroid + +[Term] +id: GO:0009730 +name: detection of carbohydrate stimulus +namespace: biological_process +def: "The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of carbohydrate stimulus" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0009743 ! response to carbohydrate + +[Term] +id: GO:0009731 +name: detection of sucrose stimulus +namespace: biological_process +def: "The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of sucrose stimulus" RELATED [] +is_a: GO:0009744 ! response to sucrose +is_a: GO:0034288 ! detection of disaccharide stimulus + +[Term] +id: GO:0009732 +name: detection of hexose stimulus +namespace: biological_process +def: "The series of events in which a stimulus from a hexose is received and converted into a molecular signal." [GOC:sm] +synonym: "perception of hexose stimulus" RELATED [] +is_a: GO:0009746 ! response to hexose +is_a: GO:0034287 ! detection of monosaccharide stimulus + +[Term] +id: GO:0009733 +name: response to auxin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus." [GOC:jl] +synonym: "response to auxin stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone + +[Term] +id: GO:0009734 +name: auxin-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:sm, PMID:16990790, PMID:18647826] +synonym: "auxin mediated signaling pathway" RELATED [] +synonym: "auxin mediated signalling" EXACT [] +synonym: "auxin signal transduction" EXACT [PMID:16990790] +synonym: "auxin signaling" EXACT [PMID:18647826] +synonym: "auxin-regulated transcription" RELATED [PMID:15917797] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071365 ! cellular response to auxin stimulus + +[Term] +id: GO:0009735 +name: response to cytokinin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus." [GOC:jl] +synonym: "response to cytokinin stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone + +[Term] +id: GO:0009736 +name: cytokinin-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:sm, PMID:24080474] +synonym: "cytokinin mediated signaling pathway" RELATED [] +synonym: "cytokinin mediated signalling" EXACT [] +synonym: "cytokinin signaling" EXACT [PMID:24080474] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071368 ! cellular response to cytokinin stimulus + +[Term] +id: GO:0009737 +name: response to abscisic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus." [GOC:jl] +synonym: "response to abscisic acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009725 ! response to hormone +is_a: GO:0033993 ! response to lipid +is_a: GO:0097305 ! response to alcohol + +[Term] +id: GO:0009738 +name: abscisic acid-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription." [GOC:signaling, GOC:sm, PMID:24269821] +synonym: "ABA signal transduction" EXACT [PMID:20713515] +synonym: "ABA signaling" EXACT [PMID:24269821] +synonym: "abscisic acid mediated signalling" EXACT [] +synonym: "abscisic acid signal transduction" RELATED [PMID:20713515] +synonym: "abscisic acid-mediated signaling pathway" RELATED [] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071215 ! cellular response to abscisic acid stimulus + +[Term] +id: GO:0009739 +name: response to gibberellin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus." [GOC:jl] +synonym: "response to gibberellic acid stimulus" NARROW [] +synonym: "response to gibberellin stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009725 ! response to hormone +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009740 +name: gibberellic acid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of gibberellic acid." [GOC:sm] +synonym: "GA-signaling" EXACT [] +synonym: "gibberellic acid mediated signalling" EXACT [] +synonym: "gibberellic acid signaling" EXACT [] +is_a: GO:0010476 ! gibberellin mediated signaling pathway + +[Term] +id: GO:0009741 +name: response to brassinosteroid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus." [GOC:jl] +synonym: "response to brassinosteroid stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009742 +name: brassinosteroid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of brassinosteroid." [GOC:sm] +synonym: "brassinosteroid mediated signalling" EXACT [] +is_a: GO:0043401 ! steroid hormone mediated signaling pathway +relationship: part_of GO:0071367 ! cellular response to brassinosteroid stimulus + +[Term] +id: GO:0009743 +name: response to carbohydrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] +synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009744 +name: response to sucrose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus." [GOC:jl] +synonym: "response to sucrose stimulus" EXACT [GOC:dos] +is_a: GO:0034285 ! response to disaccharide + +[Term] +id: GO:0009745 +name: sucrose mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of sucrose." [GOC:sm] +synonym: "sucrose mediated signalling" EXACT [] +is_a: GO:0010182 ! sugar mediated signaling pathway +relationship: part_of GO:0071329 ! cellular response to sucrose stimulus + +[Term] +id: GO:0009746 +name: response to hexose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] +synonym: "response to hexose stimulus" EXACT [GOC:dos] +is_a: GO:0034284 ! response to monosaccharide + +[Term] +id: GO:0009747 +name: hexokinase-dependent signaling +namespace: biological_process +def: "A series of molecular signals mediated by hexose and dependent on the detection of hexokinase." [GOC:mah, GOC:sm] +synonym: "hexokinase-dependent signalling" EXACT [] +is_a: GO:0009757 ! hexose mediated signaling + +[Term] +id: GO:0009748 +name: hexokinase-independent signaling +namespace: biological_process +def: "A series of molecular signals mediated by hexose and independent of hexokinase." [GOC:mah, GOC:sm] +synonym: "hexokinase-independent signalling" EXACT [] +is_a: GO:0009757 ! hexose mediated signaling + +[Term] +id: GO:0009749 +name: response to glucose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] +synonym: "response to glucose stimulus" EXACT [GOC:dos] +is_a: GO:0009746 ! response to hexose + +[Term] +id: GO:0009750 +name: response to fructose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus." [GOC:jl] +synonym: "response to fructose stimulus" EXACT [GOC:dos] +is_a: GO:0009746 ! response to hexose + +[Term] +id: GO:0009751 +name: response to salicylic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus." [GOC:jl] +synonym: "response to salicylate" EXACT [GOC:dph] +synonym: "response to salicylic acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009752 +name: detection of salicylic acid stimulus +namespace: biological_process +def: "The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "perception of salicylic acid stimulus" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0009751 ! response to salicylic acid + +[Term] +id: GO:0009753 +name: response to jasmonic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus." [GOC:jl] +synonym: "response to jasmonic acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009725 ! response to hormone +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0009754 +name: detection of jasmonic acid stimulus +namespace: biological_process +def: "The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule." [GOC:sm] +synonym: "perception of jasmonic acid stimulus" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0009726 ! detection of endogenous stimulus +is_a: GO:0009753 ! response to jasmonic acid + +[Term] +id: GO:0009755 +name: hormone-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of a hormone." [GOC:sm] +synonym: "hormone mediated signalling" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0032870 ! cellular response to hormone stimulus + +[Term] +id: GO:0009756 +name: carbohydrate mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of carbohydrate." [GOC:sm] +synonym: "carbohydrate mediated signalling" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0071322 ! cellular response to carbohydrate stimulus + +[Term] +id: GO:0009757 +name: hexose mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of hexose." [GOC:sm] +synonym: "hexose mediated signalling" EXACT [] +is_a: GO:0010182 ! sugar mediated signaling pathway +relationship: part_of GO:0071331 ! cellular response to hexose stimulus + +[Term] +id: GO:0009758 +name: carbohydrate utilization +namespace: biological_process +alt_id: GO:0007587 +def: "A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism." [GOC:mah, GOC:mcc2, GOC:mlg] +synonym: "sugar utilization" NARROW [GOC:mcc2] +is_a: GO:0008150 ! biological_process +relationship: has_part GO:0005975 ! carbohydrate metabolic process +relationship: has_part GO:0008643 ! carbohydrate transport +relationship: has_part GO:0009730 ! detection of carbohydrate stimulus + +[Term] +id: GO:0009759 +name: indole glucosinolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan." [GOC:ai] +synonym: "indole glucosinolate anabolism" EXACT [] +synonym: "indole glucosinolate biosynthesis" EXACT [] +synonym: "indole glucosinolate formation" EXACT [] +synonym: "indole glucosinolate synthesis" EXACT [] +is_a: GO:0019761 ! glucosinolate biosynthetic process +is_a: GO:0042343 ! indole glucosinolate metabolic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process + +[Term] +id: GO:0009760 +name: C4 photosynthesis +namespace: biological_process +def: "The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch." [ISBN:0816017360] +xref: Wikipedia:C4_carbon_fixation +is_a: GO:0015977 ! carbon fixation +is_a: GO:0019685 ! photosynthesis, dark reaction + +[Term] +id: GO:0009761 +name: CAM photosynthesis +namespace: biological_process +def: "The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis." [ISBN:0582015952] +xref: Wikipedia:Crassulacean_acid_metabolism +is_a: GO:0015977 ! carbon fixation +is_a: GO:0019685 ! photosynthesis, dark reaction + +[Term] +id: GO:0009762 +name: NADP-malic enzyme C4 photosynthesis +namespace: biological_process +def: "The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme." [PMID:11788762] +xref: MetaCyc:PWY-241 +is_a: GO:0009760 ! C4 photosynthesis + +[Term] +id: GO:0009763 +name: NAD-malic enzyme C4 photosynthesis +namespace: biological_process +def: "The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme." [PMID:11788762] +is_a: GO:0009760 ! C4 photosynthesis + +[Term] +id: GO:0009764 +name: PEP carboxykinase C4 photosynthesis +namespace: biological_process +def: "The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK)." [PMID:11788762] +is_a: GO:0009760 ! C4 photosynthesis + +[Term] +id: GO:0009765 +name: photosynthesis, light harvesting +namespace: biological_process +def: "Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers." [GOC:sm] +synonym: "energy dissipation" RELATED [] +is_a: GO:0006091 ! generation of precursor metabolites and energy +relationship: part_of GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0009766 +name: primary charge separation +namespace: biological_process +def: "In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes." [ISBN:0792361431] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0009767 +name: photosynthetic electron transport chain +namespace: biological_process +alt_id: GO:0009774 +alt_id: GO:0009775 +alt_id: GO:0009776 +def: "A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient." [GOC:mtg_electron_transport, ISBN:0198547684] +synonym: "electron carrier, chlorophyll electron transport system" EXACT [] +synonym: "photosynthetic electron transport in cytochrome b6/f" NARROW [] +synonym: "photosynthetic electron transport in plastocyanin" NARROW [] +synonym: "photosynthetic electron transport in plastoquinone" NARROW [] +is_a: GO:0022900 ! electron transport chain +relationship: part_of GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0009768 +name: photosynthesis, light harvesting in photosystem I +namespace: biological_process +def: "After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009765 ! photosynthesis, light harvesting + +[Term] +id: GO:0009769 +name: photosynthesis, light harvesting in photosystem II +namespace: biological_process +def: "After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009765 ! photosynthesis, light harvesting + +[Term] +id: GO:0009770 +name: primary charge separation in photosystem I +namespace: biological_process +def: "Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009766 ! primary charge separation + +[Term] +id: GO:0009771 +name: primary charge separation in photosystem II +namespace: biological_process +def: "Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009766 ! primary charge separation + +[Term] +id: GO:0009772 +name: photosynthetic electron transport in photosystem II +namespace: biological_process +def: "A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009767 ! photosynthetic electron transport chain + +[Term] +id: GO:0009773 +name: photosynthetic electron transport in photosystem I +namespace: biological_process +def: "A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP." [GOC:jid, ISBN:0716731363, ISBN:0816017360] +is_a: GO:0009767 ! photosynthetic electron transport chain + +[Term] +id: GO:0009777 +name: photosynthetic phosphorylation +namespace: biological_process +def: "Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation." [ISBN:0198547684] +synonym: "photosynthetic ATP synthesis" NARROW [] +is_a: GO:0016310 ! phosphorylation +is_a: GO:0046034 ! ATP metabolic process +relationship: has_part GO:0015986 ! ATP synthesis coupled proton transport +relationship: part_of GO:0019684 ! photosynthesis, light reaction +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0009778 +name: cyclic photosynthetic phosphorylation +namespace: biological_process +def: "A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I." [ISBN:0198547684] +is_a: GO:0009777 ! photosynthetic phosphorylation + +[Term] +id: GO:0009779 +name: noncyclic photosynthetic phosphorylation +namespace: biological_process +def: "A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II." [ISBN:0198547684] +is_a: GO:0009777 ! photosynthetic phosphorylation + +[Term] +id: GO:0009780 +name: photosynthetic NADP+ reduction +namespace: biological_process +def: "An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions." [GOC:jid, ISBN:0716746840, ISBN:0816017360] +is_a: GO:0006740 ! NADPH regeneration +relationship: part_of GO:0019684 ! photosynthesis, light reaction +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0009781 +name: obsolete photosynthetic water oxidation +namespace: biological_process +def: "OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle." [GOC:jid, ISBN:0716743663, ISBN:0816017360] +comment: This term was made obsolete because it represents a molecular function. +synonym: "photosynthetic water oxidation" EXACT [] +is_obsolete: true +replaced_by: GO:0010242 + +[Term] +id: GO:0009782 +name: photosystem I antenna complex +namespace: cellular_component +def: "The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs)." [GOC:jid, ISBN:0716731363] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009522 ! photosystem I + +[Term] +id: GO:0009783 +name: photosystem II antenna complex +namespace: cellular_component +def: "The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs)." [GOC:jid, ISBN:0716731363] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009523 ! photosystem II + +[Term] +id: GO:0009784 +name: transmembrane receptor histidine kinase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate." [GOC:lr, GOC:mah] +is_a: GO:0004673 ! protein histidine kinase activity +is_a: GO:0019199 ! transmembrane receptor protein kinase activity + +[Term] +id: GO:0009785 +name: blue light signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm." [GOC:lr, GOC:sm] +synonym: "blue light signalling pathway" EXACT [] +is_a: GO:0030522 ! intracellular receptor signaling pathway +is_a: GO:0071483 ! cellular response to blue light + +[Term] +id: GO:0009786 +name: regulation of asymmetric cell division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008356 ! asymmetric cell division +relationship: regulates GO:0008356 ! asymmetric cell division + +[Term] +id: GO:0009787 +name: regulation of abscisic acid-activated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling." [GOC:lr] +synonym: "regulation of abscisic acid mediated signaling pathway" RELATED [] +synonym: "regulation of abscisic acid mediated signalling" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1905957 ! regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009738 ! abscisic acid-activated signaling pathway +relationship: regulates GO:0009738 ! abscisic acid-activated signaling pathway + +[Term] +id: GO:0009788 +name: negative regulation of abscisic acid-activated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling." [GOC:lr] +synonym: "down regulation of abscisic acid mediated signaling" EXACT [] +synonym: "down-regulation of abscisic acid mediated signaling" EXACT [] +synonym: "downregulation of abscisic acid mediated signaling" EXACT [] +synonym: "inhibition of abscisic acid mediated signaling" NARROW [] +synonym: "negative regulation of abscisic acid mediated signaling pathway" RELATED [] +synonym: "negative regulation of abscisic acid mediated signalling" EXACT [] +is_a: GO:0009787 ! regulation of abscisic acid-activated signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1905958 ! negative regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009738 ! abscisic acid-activated signaling pathway +relationship: negatively_regulates GO:0009738 ! abscisic acid-activated signaling pathway + +[Term] +id: GO:0009789 +name: positive regulation of abscisic acid-activated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling." [GOC:lr] +synonym: "activation of abscisic acid mediated signaling" NARROW [] +synonym: "positive regulation of abscisic acid mediated signaling pathway" RELATED [] +synonym: "positive regulation of abscisic acid mediated signalling" EXACT [] +synonym: "stimulation of abscisic acid mediated signaling" NARROW [] +synonym: "up regulation of abscisic acid mediated signaling" EXACT [] +synonym: "up-regulation of abscisic acid mediated signaling" EXACT [] +synonym: "upregulation of abscisic acid mediated signaling" EXACT [] +is_a: GO:0009787 ! regulation of abscisic acid-activated signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1905959 ! positive regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009738 ! abscisic acid-activated signaling pathway +relationship: positively_regulates GO:0009738 ! abscisic acid-activated signaling pathway + +[Term] +id: GO:0009790 +name: embryo development +namespace: biological_process +alt_id: GO:0009795 +def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] +subset: gocheck_do_not_manually_annotate +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +synonym: "embryogenesis" EXACT [] +synonym: "embryogenesis and morphogenesis" BROAD [] +synonym: "embryonal development" EXACT [] +xref: Wikipedia:Embryogenesis +is_a: GO:0007275 ! multicellular organism development + +[Term] +id: GO:0009791 +name: post-embryonic development +namespace: biological_process +def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] +subset: goslim_plant +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0009792 +name: embryo development ending in birth or egg hatching +namespace: biological_process +def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] +synonym: "embryogenesis" BROAD [] +is_a: GO:0009790 ! embryo development + +[Term] +id: GO:0009793 +name: embryo development ending in seed dormancy +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana." [GOC:go_curators, GOC:mtg_sensu] +synonym: "embryogenesis" BROAD [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009790 ! embryo development +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0009794 +name: regulation of mitotic cell cycle, embryonic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "embryonic mitotic cell cycle modulation" EXACT [] +synonym: "embryonic mitotic cell cycle regulation" EXACT [] +synonym: "embryonic mitotic cell cycle regulator" RELATED [] +synonym: "modulation of embryonic mitotic cell cycle progression" EXACT [] +synonym: "regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of embryonic mitotic cell cycle progression" EXACT [] +synonym: "regulation of progression through embryonic mitotic cell cycle" EXACT [] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045448 ! mitotic cell cycle, embryonic +relationship: regulates GO:0045448 ! mitotic cell cycle, embryonic + +[Term] +id: GO:0009798 +name: axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete] +synonym: "axis determination" RELATED [] +is_a: GO:0007389 ! pattern specification process + +[Term] +id: GO:0009799 +name: specification of symmetry +namespace: biological_process +def: "The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created." [GOC:go_curators] +synonym: "determination of symmetry" EXACT [GOC:dph] +is_a: GO:0007389 ! pattern specification process + +[Term] +id: GO:0009800 +name: cinnamic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid." [GOC:jl] +synonym: "cinnamic acid anabolism" EXACT [] +synonym: "cinnamic acid biosynthesis" EXACT [] +synonym: "cinnamic acid formation" EXACT [] +synonym: "cinnamic acid synthesis" EXACT [] +synonym: "cinnamylic acid biosynthesis" EXACT [] +synonym: "cinnamylic acid biosynthetic process" EXACT [] +synonym: "phenylacrylic acid biosynthesis" EXACT [] +synonym: "phenylacrylic acid biosynthetic process" EXACT [] +synonym: "phenylpropenoic acid biosynthesis" EXACT [] +synonym: "phenylpropenoic acid biosynthetic process" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009803 ! cinnamic acid metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0009801 +name: cinnamic acid ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid." [GOC:lr, GOC:yl] +synonym: "cinnamic acid ester metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process + +[Term] +id: GO:0009802 +name: cinnamic acid ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid." [GOC:jl] +synonym: "cinnamic acid ester anabolism" EXACT [] +synonym: "cinnamic acid ester biosynthesis" EXACT [] +synonym: "cinnamic acid ester formation" EXACT [] +synonym: "cinnamic acid ester synthesis" EXACT [] +synonym: "cinnamylic acid ester biosynthesis" EXACT [] +synonym: "cinnamylic acid ester biosynthetic process" EXACT [] +synonym: "phenylacrylic acid ester biosynthesis" EXACT [] +synonym: "phenylacrylic acid ester biosynthetic process" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009801 ! cinnamic acid ester metabolic process +relationship: part_of GO:0009803 ! cinnamic acid metabolic process + +[Term] +id: GO:0009803 +name: cinnamic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid." [GOC:jl] +synonym: "cinnamic acid metabolism" EXACT [] +synonym: "cinnamylic acid metabolic process" EXACT [] +synonym: "cinnamylic acid metabolism" EXACT [] +synonym: "phenylacrylic acid metabolic process" EXACT [] +synonym: "phenylacrylic acid metabolism" EXACT [] +synonym: "phenylpropenoic acid metabolic process" EXACT [] +synonym: "phenylpropenoic acid metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0009804 +name: coumarin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids." [GOC:lr, GOC:yl] +synonym: "coumarin metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0009805 +name: coumarin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids." [GOC:lr, GOC:yl] +synonym: "coumarin anabolism" EXACT [] +synonym: "coumarin biosynthesis" EXACT [] +synonym: "coumarin formation" EXACT [] +synonym: "coumarin synthesis" EXACT [] +xref: MetaCyc:PWY-5176 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009804 ! coumarin metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process + +[Term] +id: GO:0009806 +name: lignan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist." [GOC:jl, PMID:10074466] +synonym: "lignan metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process + +[Term] +id: GO:0009807 +name: lignan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist." [GOC:jl, PMID:10074466] +synonym: "lignan anabolism" EXACT [] +synonym: "lignan biosynthesis" EXACT [] +synonym: "lignan formation" EXACT [] +synonym: "lignan synthesis" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009806 ! lignan metabolic process + +[Term] +id: GO:0009808 +name: lignin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units." [GOC:lr, GOC:yl] +synonym: "lignin metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process + +[Term] +id: GO:0009809 +name: lignin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers." [GOC:tair_curators, ISBN:0198547684] +synonym: "lignin anabolism" EXACT [] +synonym: "lignin biosynthesis" EXACT [] +synonym: "lignin formation" EXACT [] +synonym: "lignin synthesis" EXACT [] +xref: MetaCyc:PWY-361 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009808 ! lignin metabolic process + +[Term] +id: GO:0009810 +name: stilbene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA." [ISBN:3110116251] +synonym: "stilbene metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:1900673 ! olefin metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0009811 +name: stilbene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA." [GOC:tair_curators, ISBN:3110116251] +synonym: "stilbene anabolism" EXACT [] +synonym: "stilbene biosynthesis" EXACT [] +synonym: "stilbene formation" EXACT [] +synonym: "stilbene synthesis" EXACT [] +is_a: GO:0009810 ! stilbene metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1900674 ! olefin biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0009812 +name: flavonoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins." [GOC:tair_curators, ISBN:0198547684] +synonym: "flavonoid metabolism" EXACT [] +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0009813 +name: flavonoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton." [GOC:tair_curators, ISBN:0198547684] +synonym: "flavonoid anabolism" EXACT [] +synonym: "flavonoid biosynthesis" EXACT [] +synonym: "flavonoid formation" EXACT [] +synonym: "flavonoid synthesis" EXACT [] +xref: MetaCyc:PWY1F-FLAVSYN +xref: Wikipedia:Flavonoid +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0009814 +name: defense response, incompatible interaction +namespace: biological_process +def: "A response of a plant to a pathogenic agent that prevents the occurrence or spread of disease." [GOC:lr] +synonym: "defence response incompatible interaction" EXACT [] +synonym: "defence response to pathogen, incompatible interaction" EXACT [] +synonym: "resistance response to pathogen" EXACT [] +synonym: "response to pathogen (incompatible interaction)" EXACT [] +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0009815 +name: 1-aminocyclopropane-1-carboxylate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene." [EC:1.14.17.4, RHEA:23640] +synonym: "1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)" EXACT [EC:1.14.17.4] +synonym: "ACC oxidase activity" EXACT [] +synonym: "aminocyclopropanecarboxylate oxidase activity" EXACT [EC:1.14.17.4] +synonym: "ethene-forming enzyme" BROAD [] +synonym: "ethylene-forming enzyme" BROAD [] +xref: EC:1.14.17.4 +xref: KEGG_REACTION:R07214 +xref: MetaCyc:ETHYL-RXN +xref: RHEA:23640 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0009816 +name: defense response to bacterium, incompatible interaction +namespace: biological_process +def: "A response of an organism to a bacterium that prevents the occurrence or spread of disease." [GOC:lr] +synonym: "defence response to bacterium, incompatible interaction" EXACT [] +synonym: "defence response to pathogenic bacteria, incompatible interaction" EXACT [] +synonym: "defence response to pathogenic bacterium, incompatible interaction" EXACT [] +synonym: "resistance response to pathogenic bacteria" EXACT [] +synonym: "resistance response to pathogenic bacterium" EXACT [] +synonym: "response to pathogenic bacteria (incompatible interaction)" EXACT [] +synonym: "response to pathogenic bacterium (incompatible interaction)" EXACT [] +is_a: GO:0009814 ! defense response, incompatible interaction +is_a: GO:0042742 ! defense response to bacterium + +[Term] +id: GO:0009817 +name: defense response to fungus, incompatible interaction +namespace: biological_process +def: "A response of an organism to a fungus that prevents the occurrence or spread of disease." [GOC:lr] +synonym: "defence response to fungus, incompatible interaction" EXACT [] +synonym: "defence response to pathogenic fungi, incompatible interaction" EXACT [] +synonym: "defence response to pathogenic fungus, incompatible interaction" EXACT [] +synonym: "defense response to fungi, incompatible interaction" EXACT [] +synonym: "resistance response to pathogenic fungi" EXACT [] +synonym: "resistance response to pathogenic fungus" EXACT [] +synonym: "response to pathogenic fungi (incompatible interaction)" EXACT [] +synonym: "response to pathogenic fungus (incompatible interaction)" EXACT [] +is_a: GO:0009814 ! defense response, incompatible interaction +is_a: GO:0050832 ! defense response to fungus + +[Term] +id: GO:0009818 +name: defense response to protozoan, incompatible interaction +namespace: biological_process +def: "A response of an organism to a protozoan that prevents the occurrence or spread of disease." [GOC:lr] +synonym: "defence response to pathogenic protozoa, incompatible interaction" EXACT [] +synonym: "defence response to pathogenic protozoan, incompatible interaction" EXACT [] +synonym: "defence response to protozoan, incompatible interaction" EXACT [] +synonym: "resistance response to pathogenic protozoa" EXACT [] +synonym: "resistance response to pathogenic protozoan" EXACT [] +synonym: "response to pathogenic protozoa (incompatible interaction)" EXACT [] +synonym: "response to pathogenic protozoan (incompatible interaction)" EXACT [] +is_a: GO:0009814 ! defense response, incompatible interaction +is_a: GO:0042832 ! defense response to protozoan + +[Term] +id: GO:0009819 +name: drought recovery +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition." [GOC:lr] +synonym: "drought tolerance" RELATED [] +is_a: GO:0009414 ! response to water deprivation + +[Term] +id: GO:0009820 +name: alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] +subset: goslim_chembl +synonym: "alkaloid metabolism" EXACT [] +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0009821 +name: alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [EC:1.1.1.51, GOC:lr, ISBN:0122146743] +synonym: "alkaloid anabolism" EXACT [] +synonym: "alkaloid biosynthesis" EXACT [] +synonym: "alkaloid formation" EXACT [] +synonym: "alkaloid synthesis" EXACT [] +xref: UM-BBD_enzymeID:e0711 +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0009822 +name: alkaloid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] +synonym: "alkaloid breakdown" EXACT [] +synonym: "alkaloid catabolism" EXACT [] +synonym: "alkaloid degradation" EXACT [] +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0009823 +name: cytokinin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators." [GOC:lr] +synonym: "cytokinin breakdown" EXACT [] +synonym: "cytokinin catabolism" EXACT [] +synonym: "cytokinin degradation" EXACT [] +is_a: GO:0009690 ! cytokinin metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0009824 +name: AMP dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate." [EC:2.5.1.27, RHEA:15285] +synonym: "2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity" EXACT [] +synonym: "2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity" EXACT [KEGG_REACTION:R04038] +synonym: "adenylate dimethylallyltransferase activity" EXACT [EC:2.5.1.27] +synonym: "adenylate isopentenyltransferase activity" EXACT [] +synonym: "cytokinin synthase activity" RELATED [] +synonym: "dimethylallyl-diphosphate:AMP dimethylallyltransferase activity" EXACT [EC:2.5.1.27] +synonym: "isopentenyltransferase activity" BROAD [] +xref: EC:2.5.1.27 +xref: KEGG_REACTION:R04038 +xref: MetaCyc:RXN-4307 +xref: RHEA:15285 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0009825 +name: multidimensional cell growth +namespace: biological_process +def: "The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes." [ISBN:0943088399] +synonym: "cell growth in three dimensions" EXACT [] +synonym: "cell growth in two dimensions" NARROW [] +is_a: GO:0016049 ! cell growth + +[Term] +id: GO:0009826 +name: unidimensional cell growth +namespace: biological_process +def: "The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell." [ISBN:0943088399] +comment: Unidimensional cell growth refers to a change in both cell size and cell shape. For cell shape changes where cell size is not affected, consider instead the term 'regulation of cell shape ; GO:0008360' and its children. +synonym: "cell elongation" NARROW [] +synonym: "cell growth along one axis" EXACT [] +synonym: "cell growth in one dimension" EXACT [] +synonym: "cell morphogenesis by unidimensional growth" EXACT [GOC:dph, GOC:tb] +synonym: "polar cell growth" EXACT [] +synonym: "polarized cell growth" EXACT [] +is_a: GO:0000902 ! cell morphogenesis +is_a: GO:0016049 ! cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis + +[Term] +id: GO:0009827 +name: plant-type cell wall modification +namespace: biological_process +def: "The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +synonym: "cellulose and pectin-containing cell wall modification" EXACT [] +is_a: GO:0009664 ! plant-type cell wall organization +is_a: GO:0042545 ! cell wall modification + +[Term] +id: GO:0009828 +name: plant-type cell wall loosening +namespace: biological_process +def: "The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +synonym: "cellulose and pectin-containing cell wall loosening" EXACT [] +is_a: GO:0009827 ! plant-type cell wall modification + +[Term] +id: GO:0009829 +name: cell wall modification involved in fruit ripening +namespace: biological_process +def: "The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening." [GOC:lr] +synonym: "cell wall modification during ripening" RELATED [GOC:dph, GOC:tb] +is_a: GO:0009827 ! plant-type cell wall modification +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +intersection_of: GO:0042545 ! cell wall modification +intersection_of: part_of GO:0009835 ! fruit ripening +relationship: part_of GO:0009835 ! fruit ripening + +[Term] +id: GO:0009830 +name: cell wall modification involved in abscission +namespace: biological_process +def: "A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission." [GOC:dph, GOC:lr, GOC:sdb_2009, GOC:tb] +synonym: "cell wall modification during abscission" RELATED [GOC:dph, GOC:tb] +is_a: GO:0009827 ! plant-type cell wall modification +is_a: GO:0044277 ! cell wall disassembly +intersection_of: GO:0042545 ! cell wall modification +intersection_of: part_of GO:0009838 ! abscission +relationship: part_of GO:0009838 ! abscission + +[Term] +id: GO:0009831 +name: plant-type cell wall modification involved in multidimensional cell growth +namespace: biological_process +def: "The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +synonym: "cell wall modification during cell expansion" BROAD [] +synonym: "cellulose and pectin-containing cell wall modification during multidimensional cell growth" RELATED [] +is_a: GO:0009827 ! plant-type cell wall modification +is_a: GO:0042547 ! cell wall modification involved in multidimensional cell growth +intersection_of: GO:0009827 ! plant-type cell wall modification +intersection_of: part_of GO:0009825 ! multidimensional cell growth + +[Term] +id: GO:0009832 +name: plant-type cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana." [GOC:go_curators, GOC:lr, GOC:mtg_sensu] +synonym: "cell wall anabolism" BROAD [] +synonym: "cell wall assembly" BROAD [] +synonym: "cell wall biosynthetic process" BROAD [] +synonym: "cell wall formation" BROAD [] +synonym: "cell wall synthesis" BROAD [] +synonym: "cellulose and pectin-containing cell wall biogenesis" EXACT [] +is_a: GO:0042546 ! cell wall biogenesis +is_a: GO:0071669 ! plant-type cell wall organization or biogenesis + +[Term] +id: GO:0009833 +name: plant-type primary cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +synonym: "cellulose and pectin-containing primary cell wall biogenesis" EXACT [] +synonym: "primary cell wall anabolism" BROAD [] +synonym: "primary cell wall biogenesis" EXACT [] +synonym: "primary cell wall biosynthetic process" BROAD [] +synonym: "primary cell wall formation" BROAD [] +synonym: "primary cell wall synthesis" BROAD [] +is_a: GO:0009832 ! plant-type cell wall biogenesis +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0000281 ! mitotic cytokinesis + +[Term] +id: GO:0009834 +name: plant-type secondary cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana." [GOC:lr, GOC:mtg_sensu] +synonym: "cellulose and pectin-containing secondary cell wall biogenesis" EXACT [] +synonym: "secondary cell wall anabolism" BROAD [] +synonym: "secondary cell wall biogenesis" EXACT [] +synonym: "secondary cell wall biosynthetic process" BROAD [] +synonym: "secondary cell wall formation" BROAD [] +synonym: "secondary cell wall synthesis" BROAD [] +is_a: GO:0009832 ! plant-type cell wall biogenesis + +[Term] +id: GO:0009835 +name: fruit ripening +namespace: biological_process +def: "An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal." [GOC:lr] +subset: goslim_plant +synonym: "fruit maturation" RELATED [GOC:PO_curators] +synonym: "fruit senescence" RELATED [GOC:PO_curators] +xref: Wikipedia:Ripening +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0007568 ! aging +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0010154 ! fruit development + +[Term] +id: GO:0009836 +name: fruit ripening, climacteric +namespace: biological_process +def: "A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset." [GOC:lr, ISBN:0521587840] +is_a: GO:0009835 ! fruit ripening + +[Term] +id: GO:0009837 +name: fruit ripening, non-climacteric +namespace: biological_process +def: "A fruit ripening process that does not involve a respiratory burst." [GOC:lr, ISBN:0521587840] +is_a: GO:0009835 ! fruit ripening + +[Term] +id: GO:0009838 +name: abscission +namespace: biological_process +def: "The controlled shedding of a body part." [ISBN:0140514031] +subset: goslim_plant +xref: Wikipedia:Abscission +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0009839 +name: obsolete SCF complex substrate recognition subunit +namespace: cellular_component +def: "OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex." [PMID:11790542, PMID:9857172] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "SCF complex substrate recognition subunit" EXACT [] +is_obsolete: true +replaced_by: GO:0019005 + +[Term] +id: GO:0009840 +name: chloroplastic endopeptidase Clp complex +namespace: cellular_component +def: "A Clp endopeptidase complex located in the chloroplast." [GOC:mah] +is_a: GO:0009368 ! endopeptidase Clp complex +intersection_of: GO:0009368 ! endopeptidase Clp complex +intersection_of: part_of GO:0009570 ! chloroplast stroma +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0009841 +name: mitochondrial endopeptidase Clp complex +namespace: cellular_component +def: "A Clp endopeptidase complex located in the mitochondrion." [GOC:mah] +is_a: GO:0009368 ! endopeptidase Clp complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0009368 ! endopeptidase Clp complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0009842 +name: cyanelle +namespace: cellular_component +def: "A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid." [ISBN:0521316871, ISBN:1402001894] +synonym: "cyanoplast" EXACT [ISBN:1402001894] +synonym: "muroplast" EXACT [ISBN:1402001894] +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0009843 +name: cyanelle thylakoid +namespace: cellular_component +def: "A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria." [GOC:lr, GOC:mah, GOC:mtg_sensu] +is_a: GO:0031976 ! plastid thylakoid +intersection_of: GO:0009579 ! thylakoid +intersection_of: part_of GO:0009842 ! cyanelle +relationship: part_of GO:0009842 ! cyanelle + +[Term] +id: GO:0009844 +name: obsolete germination +namespace: biological_process +alt_id: GO:0009565 +def: "OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth." [GOC:lr] +comment: This term was made obsolete because it is a grouping term without biological significance. +synonym: "germination" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009845 +name: seed germination +namespace: biological_process +def: "The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis." [PMID:8281041] +xref: Wikipedia:Germination#Seed_germination +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0090351 ! seedling development + +[Term] +id: GO:0009846 +name: pollen germination +namespace: biological_process +def: "The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture." [GOC:lr, http://www.bio.uu.nl, ISBN:0943088399] +is_a: GO:0022414 ! reproductive process +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0009856 ! pollination + +[Term] +id: GO:0009847 +name: spore germination +namespace: biological_process +def: "The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall)." [GOC:lr] +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0009848 +name: indoleacetic acid biosynthetic process via tryptophan +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan." [GOC:lm, GOC:lr, PMID:10375566] +synonym: "IAA biosynthetic process via tryptophan" EXACT [] +synonym: "indoleacetic acid anabolism via tryptophan" EXACT [] +synonym: "indoleacetic acid formation via tryptophan" EXACT [] +synonym: "indoleacetic acid synthesis via tryptophan" EXACT [] +xref: MetaCyc:PWY-581 +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0009684 ! indoleacetic acid biosynthetic process + +[Term] +id: GO:0009849 +name: tryptophan-independent indoleacetic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan." [GOC:go_curators, GOC:lm, GOC:lr, PMID:10375566] +synonym: "indoleacetic acid biosynthesis, tryptophan-independent" EXACT [] +synonym: "indoleacetic acid biosynthetic process, tryptophan-independent" EXACT [] +synonym: "tryptophan-independent IAA biosynthetic process" EXACT [] +synonym: "tryptophan-independent indoleacetic acid anabolism" EXACT [] +synonym: "tryptophan-independent indoleacetic acid biosynthesis" EXACT [] +synonym: "tryptophan-independent indoleacetic acid formation" EXACT [] +synonym: "tryptophan-independent indoleacetic acid synthesis" EXACT [] +xref: MetaCyc:PWY-581 +is_a: GO:0009684 ! indoleacetic acid biosynthetic process + +[Term] +id: GO:0009850 +name: auxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth." [GOC:lr] +synonym: "auxin metabolism" EXACT [] +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0009851 +name: auxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth." [GOC:lm, GOC:lr, ISBN:0122146743] +synonym: "auxin anabolism" EXACT [] +synonym: "auxin biosynthesis" EXACT [] +synonym: "auxin formation" EXACT [] +synonym: "auxin synthesis" EXACT [] +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0009852 +name: auxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth." [GOC:lm, GOC:lr, ISBN:0198547684] +synonym: "auxin breakdown" EXACT [] +synonym: "auxin catabolism" EXACT [] +synonym: "auxin degradation" EXACT [] +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0009853 +name: photorespiration +namespace: biological_process +def: "A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria." [ISBN:0198506732] +xref: MetaCyc:PWY-181 +xref: Wikipedia:Photorespiration +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0009854 +name: oxidative photosynthetic carbon pathway +namespace: biological_process +def: "The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2)." [ISBN:0943088399] +is_a: GO:0043094 ! cellular metabolic compound salvage +relationship: part_of GO:0009853 ! photorespiration + +[Term] +id: GO:0009855 +name: determination of bilateral symmetry +namespace: biological_process +def: "The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry." [GOC:go_curators] +synonym: "determination of bilateral asymmetry" EXACT [GOC:dph] +is_a: GO:0009799 ! specification of symmetry + +[Term] +id: GO:0009856 +name: pollination +namespace: biological_process +def: "The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion." [GOC:tb, PMID:10973091] +subset: goslim_plant +xref: Wikipedia:Pollination +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0044706 ! multi-multicellular organism process + +[Term] +id: GO:0009858 +name: obsolete compatible pollen-pistil interaction +namespace: biological_process +def: "OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style." [GOC:lr, ISBN:0387987819] +comment: This term was made obsolete because it represents a phenotype. +synonym: "compatible pollen-pistil interaction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009859 +name: pollen hydration +namespace: biological_process +def: "The process in which water is taken up by pollen." [GOC:lr] +is_a: GO:0006833 ! water transport +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0009875 ! pollen-pistil interaction + +[Term] +id: GO:0009860 +name: pollen tube growth +namespace: biological_process +def: "Growth of pollen via tip extension of the intine wall." [ISBN:0943088399] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009932 ! cell tip growth +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0048868 ! pollen tube development + +[Term] +id: GO:0009861 +name: jasmonic acid and ethylene-dependent systemic resistance +namespace: biological_process +def: "The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen." [GOC:jy, PMID:10234273] +synonym: "jasmonic acid and ethene-dependent systemic resistance" EXACT [] +synonym: "jasmonic acid/ethylene-dependent systemic resistance" EXACT [] +is_a: GO:0009611 ! response to wounding +is_a: GO:0009814 ! defense response, incompatible interaction + +[Term] +id: GO:0009862 +name: systemic acquired resistance, salicylic acid mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance." [GOC:jy] +synonym: "salicylic acid mediated signaling pathway (systemic acquired resistance)" EXACT [] +synonym: "systemic acquired resistance, salicylic acid mediated signalling pathway" EXACT [] +is_a: GO:0009863 ! salicylic acid mediated signaling pathway +intersection_of: GO:0009863 ! salicylic acid mediated signaling pathway +intersection_of: part_of GO:0009627 ! systemic acquired resistance +relationship: part_of GO:0009627 ! systemic acquired resistance + +[Term] +id: GO:0009863 +name: salicylic acid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by salicylic acid." [GOC:jy] +synonym: "salicylic acid mediated signal transduction" EXACT [GOC:signaling] +synonym: "salicylic acid mediated signalling pathway" EXACT [] +synonym: "salicylic acid-mediated signaling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0071446 ! cellular response to salicylic acid stimulus + +[Term] +id: GO:0009864 +name: induced systemic resistance, jasmonic acid mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance." [GOC:jy] +synonym: "induced systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] +synonym: "jasmonic acid mediated signaling pathway (induced systemic resistance)" EXACT [] +is_a: GO:0002218 ! activation of innate immune response +is_a: GO:0002252 ! immune effector process +is_a: GO:0009867 ! jasmonic acid mediated signaling pathway +intersection_of: GO:0009867 ! jasmonic acid mediated signaling pathway +intersection_of: part_of GO:0009682 ! induced systemic resistance +relationship: part_of GO:0009682 ! induced systemic resistance + +[Term] +id: GO:0009865 +name: pollen tube adhesion +namespace: biological_process +def: "The process in which the pollen tube adheres to cells of the stigma and style." [GOC:tair_curators, PMID:12602877] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051703 ! intraspecies interaction between organisms +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0009875 ! pollen-pistil interaction +relationship: part_of GO:0048868 ! pollen tube development + +[Term] +id: GO:0009866 +name: induced systemic resistance, ethylene mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance." [GOC:jy] +synonym: "ethene mediated signaling pathway (induced systemic resistance)" EXACT [] +synonym: "ethylene mediated signaling pathway (induced systemic resistance)" EXACT [] +synonym: "induced systemic resistance, ethene mediated signaling pathway" EXACT [] +synonym: "induced systemic resistance, ethene mediated signalling pathway" EXACT [] +synonym: "induced systemic resistance, ethylene mediated signalling pathway" EXACT [] +is_a: GO:0002218 ! activation of innate immune response +is_a: GO:0002252 ! immune effector process +is_a: GO:0009873 ! ethylene-activated signaling pathway +intersection_of: GO:0009873 ! ethylene-activated signaling pathway +intersection_of: part_of GO:0009682 ! induced systemic resistance +relationship: part_of GO:0009682 ! induced systemic resistance + +[Term] +id: GO:0009867 +name: jasmonic acid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by jasmonic acid." [GOC:jy, PMID:16478936, PMID:19522558, PMID:20159850] +synonym: "JA signaling" EXACT [PMID:20159850] +synonym: "jasmonate signaling" RELATED [PMID:16478936] +synonym: "jasmonic acid mediated signalling pathway" EXACT [] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071395 ! cellular response to jasmonic acid stimulus + +[Term] +id: GO:0009868 +name: jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance." [GOC:jy] +synonym: "jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] +synonym: "jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)" EXACT [] +synonym: "jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)" EXACT [] +synonym: "jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] +synonym: "jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] +synonym: "jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] +synonym: "jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] +is_a: GO:0009867 ! jasmonic acid mediated signaling pathway +intersection_of: GO:0009867 ! jasmonic acid mediated signaling pathway +intersection_of: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance +relationship: part_of GO:0032260 ! response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance + +[Term] +id: GO:0009869 +name: obsolete incompatible pollen-pistil interaction +namespace: biological_process +def: "OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth." [PMID:10375566] +comment: This term was made obsolete because it represents a phenotype. +synonym: "incompatible pollen-pistil interaction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009870 +name: defense response signaling pathway, resistance gene-dependent +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response." [GOC:jy, GOC:mah, PMID:11418339, PMID:28105028] +synonym: "defence response signaling pathway, resistance gene-dependent" EXACT [] +synonym: "defence response signalling pathway, resistance gene-dependent" EXACT [] +synonym: "defense response signalling pathway, resistance gene-dependent" EXACT [] +synonym: "effector triggered immunity" BROAD [] +synonym: "effector-triggered immune signaling" EXACT [] +synonym: "effector-triggered immunity" BROAD [] +is_a: GO:0002758 ! innate immune response-activating signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18586 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18733 xsd:anyURI + +[Term] +id: GO:0009871 +name: jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance." [GOC:jy] +synonym: "ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)" EXACT [] +synonym: "ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)" EXACT [] +synonym: "jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway" EXACT [] +synonym: "jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway" EXACT [] +synonym: "jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway" EXACT [] +synonym: "jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway" EXACT [] +synonym: "jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway" EXACT [] +is_a: GO:0009873 ! ethylene-activated signaling pathway +intersection_of: GO:0009873 ! ethylene-activated signaling pathway +intersection_of: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance +relationship: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance + +[Term] +id: GO:0009872 +name: obsolete gametophytic self-incompatibility +namespace: biological_process +def: "OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place." [ISBN:0387987819] +comment: This term was made obsolete because it represents a phenotype. +synonym: "gametophytic self-incompatibility" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009873 +name: ethylene-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription." [GOC:jy, PMID:24012247] +synonym: "ethene mediated signaling pathway" RELATED [] +synonym: "ethene mediated signalling pathway" EXACT [] +synonym: "ethylene mediated signaling pathway" RELATED [] +synonym: "ethylene mediated signalling pathway" RELATED [] +synonym: "ethylene signal transduction" RELATED [PMID:24012247] +synonym: "ethylene signaling pathway" RELATED [PMID:24287137] +is_a: GO:0000160 ! phosphorelay signal transduction system +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071369 ! cellular response to ethylene stimulus + +[Term] +id: GO:0009874 +name: obsolete sporophytic self-incompatibility +namespace: biological_process +def: "OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place." [ISBN:0387987819] +comment: This term was made obsolete because it represents a phenotype. +synonym: "sporophytic self-incompatibility" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009875 +name: pollen-pistil interaction +namespace: biological_process +def: "The interaction between a pollen grain and pistil." [PMID:27899537] +synonym: "pollen-gynoecium interaction" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0009856 ! pollination + +[Term] +id: GO:0009876 +name: pollen adhesion +namespace: biological_process +def: "The process in which pollen deposited on the stigma adheres to cells of the stigma." [GOC:tair_curators] +is_a: GO:0022414 ! reproductive process +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0009875 ! pollen-pistil interaction + +[Term] +id: GO:0009877 +name: nodulation +namespace: biological_process +def: "The formation of nitrogen-fixing root nodules on plant roots." [UniProtKB-KW:KW-0536] +synonym: "nodule development" EXACT [GOC:jl] +synonym: "nodule formation" EXACT [GOC:jl] +is_a: GO:0044403 ! symbiotic process + +[Term] +id: GO:0009878 +name: nodule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nodule are generated and organized." [GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0044111 ! development involved in symbiotic interaction +intersection_of: GO:0009653 ! anatomical structure morphogenesis +intersection_of: part_of GO:0009877 ! nodulation +relationship: part_of GO:0009877 ! nodulation + +[Term] +id: GO:0009879 +name: determination of radial symmetry +namespace: biological_process +def: "The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis." [GOC:go_curators] +synonym: "determination of radial asymmetry" EXACT [GOC:dph] +is_a: GO:0009799 ! specification of symmetry +relationship: part_of GO:0009956 ! radial pattern formation + +[Term] +id: GO:0009880 +name: embryonic pattern specification +namespace: biological_process +def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125] +synonym: "embryonic pattern biosynthesis" BROAD [] +synonym: "embryonic pattern formation" BROAD [] +synonym: "ventral/lateral system" RELATED [] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0009881 +name: photoreceptor activity +namespace: molecular_function +def: "The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation." [GOC:ai, GOC:go_curators] +synonym: "blue-sensitive opsin" NARROW [] +synonym: "green-sensitive opsin" NARROW [] +synonym: "long-wave-sensitive opsin" NARROW [] +synonym: "opsin" NARROW [] +synonym: "red-sensitive opsin" NARROW [] +synonym: "short-wave-sensitive opsin" NARROW [] +synonym: "UV-sensitive opsin" NARROW [] +synonym: "violet-sensitive opsin" NARROW [] +xref: Reactome:R-HSA-2465917 "Photons induce isomerisation of 11c-retinyl to at-retinyl" +xref: Reactome:R-HSA-74101 "Photons induce isomerization of 11c-retinyl to at-retinyl" +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0009882 +name: blue light photoreceptor activity +namespace: molecular_function +def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation." [GOC:tb] +is_a: GO:0009881 ! photoreceptor activity +relationship: part_of GO:0009785 ! blue light signaling pathway + +[Term] +id: GO:0009883 +name: red or far-red light photoreceptor activity +namespace: molecular_function +def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation." [GOC:lr] +synonym: "red/far-red light photoreceptor activity" EXACT [] +is_a: GO:0009881 ! photoreceptor activity +relationship: part_of GO:0009585 ! red, far-red light phototransduction + +[Term] +id: GO:0009884 +name: cytokinin receptor activity +namespace: molecular_function +def: "Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:lr, GOC:signaling] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0009736 ! cytokinin-activated signaling pathway + +[Term] +id: GO:0009885 +name: transmembrane histidine kinase cytokinin receptor activity +namespace: molecular_function +def: "Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate." [GOC:lr, GOC:mah] +is_a: GO:0009784 ! transmembrane receptor histidine kinase activity +is_a: GO:0009884 ! cytokinin receptor activity + +[Term] +id: GO:0009886 +name: post-embryonic animal morphogenesis +namespace: biological_process +def: "The process, occurring after animal embryonic development, by which anatomical structures are generated and organized." [GOC:go_curators] +synonym: "post-embryonic morphogenesis of an anatomical structure" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0009791 ! post-embryonic development + +[Term] +id: GO:0009887 +name: animal organ morphogenesis +namespace: biological_process +def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544] +synonym: "histogenesis and organogenesis" BROAD [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0009888 +name: tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] +synonym: "histogenesis" EXACT [] +synonym: "histogenesis and organogenesis" BROAD [] +xref: Wikipedia:Histogenesis +is_a: GO:0048856 ! anatomical structure development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:33630 +property_value: RO:0002161 NCBITaxon:33682 +property_value: RO:0002161 NCBITaxon:38254 +property_value: RO:0002161 NCBITaxon:4891 + +[Term] +id: GO:0009889 +name: regulation of biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] +synonym: "regulation of anabolism" EXACT [] +synonym: "regulation of biosynthesis" EXACT [] +synonym: "regulation of formation" EXACT [] +synonym: "regulation of synthesis" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009058 ! biosynthetic process +relationship: regulates GO:0009058 ! biosynthetic process + +[Term] +id: GO:0009890 +name: negative regulation of biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] +synonym: "down regulation of biosynthetic process" EXACT [] +synonym: "down-regulation of biosynthetic process" EXACT [] +synonym: "downregulation of biosynthetic process" EXACT [] +synonym: "inhibition of biosynthetic process" NARROW [] +synonym: "negative regulation of anabolism" EXACT [] +synonym: "negative regulation of biosynthesis" EXACT [] +synonym: "negative regulation of formation" EXACT [] +synonym: "negative regulation of synthesis" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0009892 ! negative regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009058 ! biosynthetic process +relationship: negatively_regulates GO:0009058 ! biosynthetic process + +[Term] +id: GO:0009891 +name: positive regulation of biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] +synonym: "activation of biosynthetic process" NARROW [] +synonym: "positive regulation of anabolism" EXACT [] +synonym: "positive regulation of biosynthesis" EXACT [] +synonym: "positive regulation of formation" EXACT [] +synonym: "positive regulation of synthesis" EXACT [] +synonym: "stimulation of biosynthetic process" NARROW [] +synonym: "up regulation of biosynthetic process" EXACT [] +synonym: "up-regulation of biosynthetic process" EXACT [] +synonym: "upregulation of biosynthetic process" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0009893 ! positive regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009058 ! biosynthetic process +relationship: positively_regulates GO:0009058 ! biosynthetic process + +[Term] +id: GO:0009892 +name: negative regulation of metabolic process +namespace: biological_process +alt_id: GO:0044252 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] +synonym: "down regulation of metabolic process" EXACT [] +synonym: "down-regulation of metabolic process" EXACT [] +synonym: "downregulation of metabolic process" EXACT [] +synonym: "inhibition of metabolic process" NARROW [] +synonym: "inhibition of organismal metabolic process" NARROW [] +synonym: "negative regulation of metabolism" EXACT [] +synonym: "negative regulation of multicellular organismal metabolic process" NARROW [] +synonym: "negative regulation of organismal metabolism" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008152 ! metabolic process +relationship: negatively_regulates GO:0008152 ! metabolic process + +[Term] +id: GO:0009893 +name: positive regulation of metabolic process +namespace: biological_process +alt_id: GO:0044253 +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] +synonym: "activation of metabolic process" NARROW [] +synonym: "positive regulation of metabolism" EXACT [] +synonym: "positive regulation of multicellular organismal metabolic process" NARROW [] +synonym: "positive regulation of organismal metabolism" NARROW [] +synonym: "stimulation of metabolic process" NARROW [] +synonym: "stimulation of organismal metabolic process" NARROW [] +synonym: "up regulation of metabolic process" EXACT [] +synonym: "up-regulation of metabolic process" EXACT [] +synonym: "up-regulation of organismal metabolic process" NARROW [] +synonym: "upregulation of metabolic process" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008152 ! metabolic process +relationship: positively_regulates GO:0008152 ! metabolic process + +[Term] +id: GO:0009894 +name: regulation of catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] +synonym: "regulation of breakdown" EXACT [] +synonym: "regulation of catabolism" EXACT [] +synonym: "regulation of degradation" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009056 ! catabolic process +relationship: regulates GO:0009056 ! catabolic process + +[Term] +id: GO:0009895 +name: negative regulation of catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] +synonym: "down regulation of catabolic process" EXACT [] +synonym: "down-regulation of catabolic process" EXACT [] +synonym: "downregulation of catabolic process" EXACT [] +synonym: "inhibition of catabolic process" NARROW [] +synonym: "negative regulation of breakdown" EXACT [] +synonym: "negative regulation of catabolism" EXACT [] +synonym: "negative regulation of degradation" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0009894 ! regulation of catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009056 ! catabolic process +relationship: negatively_regulates GO:0009056 ! catabolic process + +[Term] +id: GO:0009896 +name: positive regulation of catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] +synonym: "activation of catabolic process" NARROW [] +synonym: "positive regulation of breakdown" EXACT [] +synonym: "positive regulation of catabolism" EXACT [] +synonym: "positive regulation of degradation" EXACT [] +synonym: "stimulation of catabolic process" NARROW [] +synonym: "up regulation of catabolic process" EXACT [] +synonym: "up-regulation of catabolic process" EXACT [] +synonym: "upregulation of catabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0009894 ! regulation of catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009056 ! catabolic process +relationship: positively_regulates GO:0009056 ! catabolic process + +[Term] +id: GO:0009897 +name: external side of plasma membrane +namespace: cellular_component +def: "The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface." [GOC:dos, GOC:tb] +synonym: "external leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "juxtamembrane" BROAD [] +synonym: "outer surface of cytoplasmic membrane" EXACT [] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0009986 ! cell surface + +[Term] +id: GO:0009898 +name: cytoplasmic side of plasma membrane +namespace: cellular_component +def: "The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface." [GOC:dos, GOC:tb] +synonym: "internal leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "internal side of plasma membrane" EXACT [] +synonym: "juxtamembrane" BROAD [] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0009899 +name: ent-kaurene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate." [EC:4.2.3.19, RHEA:22220] +synonym: "ent-copalyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.19] +synonym: "ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)" EXACT [EC:4.2.3.19] +synonym: "ent-kaurene synthase B activity" NARROW [EC:4.2.3.19] +synonym: "ent-kaurene synthetase B activity" NARROW [EC:4.2.3.19] +xref: EC:4.2.3.19 +xref: KEGG_REACTION:R05092 +xref: MetaCyc:4.2.3.19-RXN +xref: RHEA:22220 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0009900 +name: dehiscence +namespace: biological_process +def: "The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it." [ISBN:0879015322] +xref: Wikipedia:Dehiscence_(botany) +is_a: GO:0048609 ! multicellular organismal reproductive process + +[Term] +id: GO:0009901 +name: anther dehiscence +namespace: biological_process +def: "The dehiscence of an anther to release the pollen grains contained within it." [GOC:tb] +is_a: GO:0009900 ! dehiscence +relationship: part_of GO:0048653 ! anther development + +[Term] +id: GO:0009902 +name: chloroplast relocation +namespace: biological_process +def: "The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery." [PMID:11309623] +synonym: "chloroplast movement" EXACT [GOC:tb, PMID:18715957] +is_a: GO:0009658 ! chloroplast organization +is_a: GO:0019750 ! chloroplast localization +is_a: GO:0051667 ! establishment of plastid localization + +[Term] +id: GO:0009903 +name: chloroplast avoidance movement +namespace: biological_process +def: "The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery." [GOC:tb, PMID:11978863] +synonym: "high-fluence-rate response" RELATED [] +is_a: GO:0009902 ! chloroplast relocation + +[Term] +id: GO:0009904 +name: chloroplast accumulation movement +namespace: biological_process +def: "The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis." [GOC:tb, PMID:11978863] +synonym: "low-fluence-rate response" RELATED [] +is_a: GO:0009902 ! chloroplast relocation + +[Term] +id: GO:0009905 +name: ent-copalyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate." [EC:5.5.1.13, RHEA:14841] +synonym: "diterpene cyclase activity" BROAD [] +synonym: "ent-copalyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.13] +synonym: "ent-kaurene synthase A activity" NARROW [EC:5.5.1.13] +synonym: "ent-kaurene synthetase A activity" NARROW [EC:5.5.1.13] +xref: EC:5.5.1.13 +xref: KEGG_REACTION:R02068 +xref: MetaCyc:5.5.1.13-RXN +xref: RHEA:14841 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0009906 +name: response to photoperiod, blue light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm." [GOC:go_curators, GOC:mtg_far_red] +is_a: GO:0009637 ! response to blue light +is_a: GO:0009648 ! photoperiodism + +[Term] +id: GO:0009907 +name: response to photoperiod, red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm." [GOC:go_curators, GOC:mtg_far_red] +is_a: GO:0009648 ! photoperiodism +is_a: GO:0010114 ! response to red light + +[Term] +id: GO:0009908 +name: flower development +namespace: biological_process +alt_id: GO:0048409 +def: "The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem." [GOC:tb, ISBN:0879015322] +subset: goslim_plant +is_a: GO:0090567 ! reproductive shoot system development + +[Term] +id: GO:0009909 +name: regulation of flower development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of flower development." [GOC:go_curators] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0048831 ! regulation of shoot system development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009908 ! flower development +relationship: regulates GO:0009908 ! flower development + +[Term] +id: GO:0009910 +name: negative regulation of flower development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of flower development." [GOC:go_curators] +synonym: "down regulation of flower development" EXACT [] +synonym: "down-regulation of flower development" EXACT [] +synonym: "downregulation of flower development" EXACT [] +synonym: "inhibition of flower development" NARROW [] +is_a: GO:0009909 ! regulation of flower development +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009908 ! flower development +relationship: negatively_regulates GO:0009908 ! flower development + +[Term] +id: GO:0009911 +name: positive regulation of flower development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of flower development." [GOC:go_curators] +synonym: "activation of flower development" NARROW [] +synonym: "stimulation of flower development" NARROW [] +synonym: "up regulation of flower development" EXACT [] +synonym: "up-regulation of flower development" EXACT [] +synonym: "upregulation of flower development" EXACT [] +is_a: GO:0009909 ! regulation of flower development +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009908 ! flower development +relationship: positively_regulates GO:0009908 ! flower development + +[Term] +id: GO:0009912 +name: auditory receptor cell fate commitment +namespace: biological_process +def: "The process in which the cellular identity of auditory hair cells is acquired and determined." [GOC:lr] +synonym: "auditory hair cell fate commitment" EXACT [] +is_a: GO:0060120 ! inner ear receptor cell fate commitment +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0042491 ! inner ear auditory receptor cell differentiation + +[Term] +id: GO:0009913 +name: epidermal cell differentiation +namespace: biological_process +alt_id: GO:0043355 +def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] +synonym: "hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0008544 ! epidermis development + +[Term] +id: GO:0009914 +name: hormone transport +namespace: biological_process +def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] +subset: goslim_pir +is_a: GO:0006810 ! transport +is_a: GO:0010817 ! regulation of hormone levels + +[Term] +id: GO:0009915 +name: phloem sucrose loading +namespace: biological_process +def: "The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink." [GOC:sm] +is_a: GO:0015770 ! sucrose transport +is_a: GO:0110126 ! phloem loading + +[Term] +id: GO:0009916 +name: alternative oxidase activity +namespace: molecular_function +def: "Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product." [ISBN:0943088399] +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0009917 +name: sterol 5-alpha reductase activity +namespace: molecular_function +def: "Catalysis of the removal of a C-5 double bond in the B ring of a sterol." [ISBN:0943088399] +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0009918 +name: sterol delta7 reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol." [ISBN:0943088399] +synonym: "sterol delta-7 reductase activity" EXACT [] +xref: MetaCyc:RXN-707 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0009919 +name: obsolete cytokinesis (sensu Viridiplantae) +namespace: biological_process +def: "OBSOLETE. The division of a cell into two daughter cells with cell walls." [GOC:tb] +comment: This term was made obsolete because its meaning was changed significantly. +synonym: "cytokinesis (sensu Viridiplantae)" EXACT [] +is_obsolete: true +consider: GO:0000911 + +[Term] +id: GO:0009920 +name: cell plate formation involved in plant-type cell wall biogenesis +namespace: biological_process +def: "The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tb, ISBN:0879015322] +synonym: "cell plate formation involved in cellulose and pectin-containing cell wall biogenesis" EXACT [] +is_a: GO:0000919 ! cell plate assembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0000919 ! cell plate assembly +intersection_of: part_of GO:0009832 ! plant-type cell wall biogenesis +relationship: part_of GO:0009832 ! plant-type cell wall biogenesis +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +relationship: part_of GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0009921 +name: auxin efflux carrier complex +namespace: cellular_component +def: "The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell." [PMID:9843496] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0009922 +name: fatty acid elongase activity +namespace: molecular_function +def: "Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C)." [GOC:tb] +xref: MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN +xref: Reactome:R-HSA-2046083 "Elongation of arachidonyl-CoA to docosatetraenoyl-CoA" +xref: Reactome:R-HSA-2046088 "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA" +xref: Reactome:R-HSA-2046090 "Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA" +xref: Reactome:R-HSA-2046094 "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA" +xref: Reactome:R-HSA-2046095 "Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA" +xref: Reactome:R-HSA-2046100 "Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA" +xref: Reactome:R-HSA-548800 "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA" +xref: Reactome:R-HSA-548814 "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA" +xref: Reactome:R-HSA-548815 "ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA" +xref: Reactome:R-HSA-548830 "ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA" +is_a: GO:0004312 ! fatty acid synthase activity + +[Term] +id: GO:0009923 +name: fatty acid elongase complex +namespace: cellular_component +def: "A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids." [GOC:tb] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0009924 +name: octadecanal decarbonylase activity +namespace: molecular_function +def: "Catalysis of the reaction: octadecanal = heptadecane + CO." [EC:4.1.99.5, GOC:tb] +synonym: "octadecanal alkane-lyase activity" EXACT [] +xref: EC:4.1.99.5 +xref: MetaCyc:OCTADECANAL-DECARBONYLASE-RXN +xref: RHEA:30415 +is_a: GO:0071771 ! aldehyde decarbonylase activity + +[Term] +id: GO:0009925 +name: basal plasma membrane +namespace: cellular_component +def: "The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis." [GOC:go_curators] +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0016323 ! basolateral plasma membrane +relationship: part_of GO:0045178 ! basal part of cell + +[Term] +id: GO:0009926 +name: auxin polar transport +namespace: biological_process +def: "The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally." [GOC:sm] +is_a: GO:0060918 ! auxin transport + +[Term] +id: GO:0009927 +name: histidine phosphotransfer kinase activity +namespace: molecular_function +def: "Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator." [PMID:11842140] +is_a: GO:0004672 ! protein kinase activity +is_a: GO:0060089 ! molecular transducer activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15611 xsd:anyURI + +[Term] +id: GO:0009930 +name: longitudinal side of cell surface +namespace: cellular_component +def: "The side of the cell parallel to the zygotic axis." [GOC:mtg_sensu, GOC:sm] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009986 ! cell surface + +[Term] +id: GO:0009931 +name: calcium-dependent protein serine/threonine kinase activity +namespace: molecular_function +def: "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions." [GOC:mah] +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0010857 ! calcium-dependent protein kinase activity + +[Term] +id: GO:0009932 +name: cell tip growth +namespace: biological_process +def: "Growth that occurs specifically at the tip of a cell." [GOC:jid] +is_a: GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0009933 +name: meristem structural organization +namespace: biological_process +def: "Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue." [GOC:sm, ISBN:0198547684] +synonym: "meristem organisation" BROAD [] +synonym: "meristem organization" BROAD [] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0048507 ! meristem development + +[Term] +id: GO:0009934 +name: regulation of meristem structural organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meristem organization." [GOC:jid] +synonym: "regulation of meristem organisation" EXACT [] +synonym: "regulation of meristem organization" BROAD [GOC:dph, GOC:tb] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0048509 ! regulation of meristem development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009933 ! meristem structural organization +relationship: regulates GO:0009933 ! meristem structural organization + +[Term] +id: GO:0009935 +name: obsolete nutrient import +namespace: biological_process +def: "OBSOLETE. The directed movement of nutrients into a cell or organelle." [GOC:sm] +comment: This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning. +synonym: "nutrient import" EXACT [] +synonym: "nutrient uptake" EXACT [] +is_obsolete: true +consider: GO:0006810 + +[Term] +id: GO:0009936 +name: obsolete expansin +namespace: molecular_function +def: "OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa." [ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "expansin" EXACT [] +is_obsolete: true +consider: GO:0009505 +consider: GO:0016049 + +[Term] +id: GO:0009937 +name: regulation of gibberellic acid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling." [GOC:go_curators] +synonym: "regulation of gibberellic acid mediated signalling" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009740 ! gibberellic acid mediated signaling pathway +relationship: regulates GO:0009740 ! gibberellic acid mediated signaling pathway + +[Term] +id: GO:0009938 +name: negative regulation of gibberellic acid mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity." [GOC:sm] +synonym: "down regulation of gibberellic acid mediated signaling" EXACT [] +synonym: "down-regulation of gibberellic acid mediated signaling" EXACT [] +synonym: "downregulation of gibberellic acid mediated signaling" EXACT [] +synonym: "inhibition of gibberellic acid mediated signaling" NARROW [] +synonym: "negative regulation of gibberellic acid mediated signalling" EXACT [] +is_a: GO:0009937 ! regulation of gibberellic acid mediated signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009740 ! gibberellic acid mediated signaling pathway +relationship: negatively_regulates GO:0009740 ! gibberellic acid mediated signaling pathway + +[Term] +id: GO:0009939 +name: positive regulation of gibberellic acid mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity." [GOC:sm] +synonym: "activation of gibberellic acid mediated signaling" NARROW [] +synonym: "positive regulation of gibberellic acid mediated signalling" EXACT [] +synonym: "stimulation of gibberellic acid mediated signaling" NARROW [] +synonym: "up regulation of gibberellic acid mediated signaling" EXACT [] +synonym: "up-regulation of gibberellic acid mediated signaling" EXACT [] +synonym: "upregulation of gibberellic acid mediated signaling" EXACT [] +is_a: GO:0009937 ! regulation of gibberellic acid mediated signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009740 ! gibberellic acid mediated signaling pathway +relationship: positively_regulates GO:0009740 ! gibberellic acid mediated signaling pathway + +[Term] +id: GO:0009940 +name: amino-terminal vacuolar sorting propeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles." [GOC:sm, PMID:10871276] +is_a: GO:0010209 ! vacuolar sorting signal binding + +[Term] +id: GO:0009941 +name: chloroplast envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:tb] +is_a: GO:0009526 ! plastid envelope +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0009942 +name: longitudinal axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root." [GOC:tb] +synonym: "apical-basal pattern specification" EXACT [] +synonym: "longitudinal axis determination" RELATED [GOC:dph] +is_a: GO:0000578 ! embryonic axis specification +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0009793 ! embryo development ending in seed dormancy + +[Term] +id: GO:0009943 +name: adaxial/abaxial axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure." [GOC:dph, GOC:tb] +synonym: "adaxial/abaxial determination" RELATED [GOC:dph] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009955 ! adaxial/abaxial pattern specification + +[Term] +id: GO:0009944 +name: polarity specification of adaxial/abaxial axis +namespace: biological_process +def: "The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure." [GOC:dph, GOC:tb] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:0009943 ! adaxial/abaxial axis specification + +[Term] +id: GO:0009945 +name: radial axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point." [GOC:dph, GOC:go_curators, GOC:isa_complete] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009956 ! radial pattern formation + +[Term] +id: GO:0009946 +name: proximal/distal axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "proximal/distal axis determination" RELATED [GOC:dph] +synonym: "proximodistal axis specification" EXACT [] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009954 ! proximal/distal pattern formation + +[Term] +id: GO:0009947 +name: centrolateral axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf." [GOC:dsz, GOC:tb, ISBN:0865427429] +synonym: "centrolateral axis determination" RELATED [GOC:dph] +synonym: "mediolateral axis specification" EXACT [] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0097353 ! centrolateral pattern formation + +[Term] +id: GO:0009948 +name: anterior/posterior axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "anterior/posterior axis determination" RELATED [GOC:dph] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009952 ! anterior/posterior pattern specification + +[Term] +id: GO:0009949 +name: polarity specification of anterior/posterior axis +namespace: biological_process +def: "Any process resulting in the establishment of polarity along the anterior/posterior axis." [GOC:go_curators] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:0009948 ! anterior/posterior axis specification + +[Term] +id: GO:0009950 +name: dorsal/ventral axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "dorsal-ventral axis specification" EXACT [GOC:mah] +synonym: "dorsal/ventral axis determination" RELATED [GOC:dph] +synonym: "dorsoventral axis specification" EXACT [GOC:mah] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009953 ! dorsal/ventral pattern formation + +[Term] +id: GO:0009951 +name: polarity specification of dorsal/ventral axis +namespace: biological_process +def: "Any process resulting in the establishment of polarity along the dorsal/ventral axis." [GOC:go_curators] +synonym: "polarity specification of dorsal-ventral axis" EXACT [GOC:mah] +synonym: "polarity specification of dorsoventral axis" EXACT [GOC:mah] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:0009950 ! dorsal/ventral axis specification + +[Term] +id: GO:0009952 +name: anterior/posterior pattern specification +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] +synonym: "anterior/posterior pattern formation" RELATED [] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0009953 +name: dorsal/ventral pattern formation +namespace: biological_process +def: "The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] +synonym: "dorsal-ventral pattern formation" EXACT [GOC:mah] +synonym: "dorsal/ventral pattern specification" NARROW [] +synonym: "dorsoventral pattern formation" EXACT [GOC:mah] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0009954 +name: proximal/distal pattern formation +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)." [GOC:dph, GOC:go_curators, GOC:isa_complete] +synonym: "proximal/distal pattern specification" NARROW [] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0009955 +name: adaxial/abaxial pattern specification +namespace: biological_process +def: "The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure." [GOC:dph, GOC:isa_complete, GOC:tb] +synonym: "adaxial/abaxial pattern formation" RELATED [] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0009956 +name: radial pattern formation +namespace: biological_process +def: "The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur." [GOC:dph, GOC:go_curators, GOC:isa_complete] +synonym: "radial pattern specification" NARROW [] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0009957 +name: epidermal cell fate specification +namespace: biological_process +alt_id: GO:0043356 +def: "The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:mtg_sensu, GOC:sm] +synonym: "hypodermal cell fate specification" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0009913 ! epidermal cell differentiation + +[Term] +id: GO:0009958 +name: positive gravitropism +namespace: biological_process +def: "The orientation of plant parts towards gravity." [GOC:sm] +synonym: "root gravitropism" NARROW [] +is_a: GO:0009630 ! gravitropism + +[Term] +id: GO:0009959 +name: negative gravitropism +namespace: biological_process +def: "The orientation of plant parts away from gravity." [GOC:sm] +synonym: "shoot gravitropism" NARROW [] +is_a: GO:0009630 ! gravitropism + +[Term] +id: GO:0009960 +name: endosperm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo." [GOC:sm] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0009961 +name: response to 1-aminocyclopropane-1-carboxylic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus." [GOC:jl] +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0009962 +name: regulation of flavonoid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] +synonym: "regulation of flavonoid anabolism" EXACT [] +synonym: "regulation of flavonoid biosynthesis" EXACT [] +synonym: "regulation of flavonoid formation" EXACT [] +synonym: "regulation of flavonoid synthesis" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009813 ! flavonoid biosynthetic process +relationship: regulates GO:0009813 ! flavonoid biosynthetic process + +[Term] +id: GO:0009963 +name: positive regulation of flavonoid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] +synonym: "activation of flavonoid biosynthetic process" NARROW [] +synonym: "positive regulation of flavonoid anabolism" EXACT [] +synonym: "positive regulation of flavonoid biosynthesis" EXACT [] +synonym: "positive regulation of flavonoid formation" EXACT [] +synonym: "positive regulation of flavonoid synthesis" EXACT [] +synonym: "stimulation of flavonoid biosynthetic process" NARROW [] +synonym: "up regulation of flavonoid biosynthetic process" EXACT [] +synonym: "up-regulation of flavonoid biosynthetic process" EXACT [] +synonym: "upregulation of flavonoid biosynthetic process" EXACT [] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0009962 ! regulation of flavonoid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009813 ! flavonoid biosynthetic process +relationship: positively_regulates GO:0009813 ! flavonoid biosynthetic process + +[Term] +id: GO:0009964 +name: negative regulation of flavonoid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] +synonym: "down regulation of flavonoid biosynthetic process" EXACT [] +synonym: "down-regulation of flavonoid biosynthetic process" EXACT [] +synonym: "downregulation of flavonoid biosynthetic process" EXACT [] +synonym: "inhibition of flavonoid biosynthetic process" NARROW [] +synonym: "negative regulation of flavonoid anabolism" EXACT [] +synonym: "negative regulation of flavonoid biosynthesis" EXACT [] +synonym: "negative regulation of flavonoid formation" EXACT [] +synonym: "negative regulation of flavonoid synthesis" EXACT [] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0009962 ! regulation of flavonoid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009813 ! flavonoid biosynthetic process +relationship: negatively_regulates GO:0009813 ! flavonoid biosynthetic process + +[Term] +id: GO:0009965 +name: leaf morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the leaf are generated and organized." [GOC:go_curators] +is_a: GO:1905392 ! plant organ morphogenesis +relationship: part_of GO:0010016 ! shoot system morphogenesis +relationship: part_of GO:0048366 ! leaf development + +[Term] +id: GO:0009966 +name: regulation of signal transduction +namespace: biological_process +alt_id: GO:0035466 +def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] +synonym: "regulation of signaling pathway" RELATED [] +synonym: "regulation of signalling pathway" RELATED [GOC:mah] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007165 ! signal transduction +relationship: regulates GO:0007165 ! signal transduction + +[Term] +id: GO:0009967 +name: positive regulation of signal transduction +namespace: biological_process +alt_id: GO:0035468 +def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] +synonym: "activation of signal transduction" NARROW [] +synonym: "positive regulation of signaling pathway" RELATED [] +synonym: "positive regulation of signalling pathway" RELATED [GOC:mah] +synonym: "stimulation of signal transduction" NARROW [] +synonym: "up regulation of signal transduction" EXACT [] +synonym: "up-regulation of signal transduction" EXACT [] +synonym: "upregulation of signal transduction" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007165 ! signal transduction +relationship: positively_regulates GO:0007165 ! signal transduction + +[Term] +id: GO:0009968 +name: negative regulation of signal transduction +namespace: biological_process +alt_id: GO:0035467 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm] +synonym: "down regulation of signal transduction" EXACT [] +synonym: "down-regulation of signal transduction" EXACT [] +synonym: "downregulation of signal transduction" EXACT [] +synonym: "inhibition of signal transduction" NARROW [] +synonym: "negative regulation of signaling pathway" RELATED [] +synonym: "negative regulation of signalling pathway" RELATED [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007165 ! signal transduction +relationship: negatively_regulates GO:0007165 ! signal transduction + +[Term] +id: GO:0009969 +name: xyloglucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants." [GOC:sm] +synonym: "xyloglucan anabolism" EXACT [] +synonym: "xyloglucan biosynthesis" EXACT [] +synonym: "xyloglucan formation" EXACT [] +synonym: "xyloglucan synthesis" EXACT [] +is_a: GO:0009250 ! glucan biosynthetic process +is_a: GO:0010411 ! xyloglucan metabolic process +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process + +[Term] +id: GO:0009970 +name: cellular response to sulfate starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate." [GOC:sm] +synonym: "cellular response to sulphate starvation" EXACT [] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0009971 +name: anastral spindle assembly involved in male meiosis +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells." [GOC:tb, PMID:11973272] +is_a: GO:0007053 ! spindle assembly involved in male meiosis +is_a: GO:0055048 ! anastral spindle assembly +intersection_of: GO:0055048 ! anastral spindle assembly +intersection_of: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0009972 +name: cytidine deamination +namespace: biological_process +def: "The removal of amino group in the presence of water." [GOC:sm] +is_a: GO:0006216 ! cytidine catabolic process + +[Term] +id: GO:0009973 +name: adenylyl-sulfate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor." [EC:1.8.99.2, PMID:5421934] +synonym: "adenosine 5'-phosphosulfate reductase" EXACT [EC:1.8.99.2] +synonym: "adenosine phosphosulfate reductase activity" EXACT [EC:1.8.99.2] +synonym: "adenylyl-sulphate reductase activity" EXACT [EC:1.8.99.2] +synonym: "AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.99.2] +synonym: "AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.99.2] +synonym: "APS reductase activity" EXACT [EC:1.8.99.2] +synonym: "APS-reductase" EXACT [EC:1.8.99.2] +xref: EC:1.8.99.2 +xref: MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN +xref: RHEA:24240 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0009974 +name: zeinoxanthin epsilon hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene." [MetaCyc:RXN-5962, PMID:8837513] +xref: EC:1.14.99 +xref: MetaCyc:RXN-5962 +is_a: GO:0072374 ! carotene epsilon hydroxylase activity + +[Term] +id: GO:0009975 +name: cyclase activity +namespace: molecular_function +def: "Catalysis of a ring closure reaction." [ISBN:0198547684] +subset: goslim_pir +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0009976 +name: tocopherol cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol)." [PMID:12213958] +is_a: GO:0009975 ! cyclase activity + +[Term] +id: GO:0009977 +name: proton motive force dependent protein transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015557 +def: "Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane." [PMID:11526245, PMID:25494301] +synonym: "arginine targeting transmembrane transporter activity" EXACT [] +synonym: "delta-pH-dependent protein transporter activity" EXACT [] +synonym: "pH-dependent protein transporter activity" EXACT [] +synonym: "twin-arginine targeting transmembrane transporter activity" EXACT [] +is_a: GO:0008320 ! protein transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0009978 +name: allene oxide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O." [EC:4.2.1.92, MetaCyc:RXN1F-19, PMID:9778849] +synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]" RELATED [EC:4.2.1.92] +synonym: "HPI" RELATED [EC:4.2.1.92] +synonym: "linoleate hydroperoxide isomerase" RELATED [EC:4.2.1.92] +synonym: "linoleic acid hydroperoxide isomerase" RELATED [EC:4.2.1.92] +xref: MetaCyc:RXN1F-19 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0009979 +name: 16:0 monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule." [GOC:mah, MetaCyc:RXN-1728, MetaCyc:RXN-8304, MetaCyc:RXN-8307] +is_a: GO:0042389 ! omega-3 fatty acid desaturase activity + +[Term] +id: GO:0009980 +name: obsolete glutamate carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups." [EC:3.4.17.11, MetaCyc:3.4.17.11-RXN] +comment: This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined. +synonym: "carboxypeptidase G activity" BROAD [EC:3.4.17.11] +synonym: "carboxypeptidase G1 activity" RELATED [EC:3.4.17.11] +synonym: "carboxypeptidase G2 activity" RELATED [EC:3.4.17.11] +synonym: "glutamate carboxypeptidase activity" EXACT [] +synonym: "glutamyl carboxypeptidase activity" EXACT [EC:3.4.17.11] +synonym: "N-pteroyl-L-glutamate hydrolase activity" EXACT [EC:3.4.17.11] +xref: EC:3.4.17.11 +xref: MetaCyc:3.4.17.11-RXN +is_obsolete: true +replaced_by: GO:0004180 + +[Term] +id: GO:0009982 +name: pseudouridine synthase activity +namespace: molecular_function +alt_id: GO:0016439 +def: "Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [GOC:mah] +comment: Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate. +xref: Reactome:R-HSA-6782381 "PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs" +xref: Reactome:R-HSA-6786583 "PUS7 transforms uridine to pseudouridine in tRNAs" +xref: Reactome:R-HSA-6787566 "PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser)" +xref: Reactome:R-HSA-6790905 "Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA" +xref: Reactome:R-HSA-8870289 "PUS3 transforms uridine-39 to pseudouridine-39 in tRNA" +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0009983 +name: obsolete tyrosine aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide." [GOC:sm, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined. +synonym: "tyrosine aminopeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0009984 +name: obsolete adenylate forming enzyme activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate." [PMID:12084835] +comment: This term was made obsolete because it does not refer to a specific reaction but rather to a process which results in the formation of AMP. +synonym: "adenylate forming enzyme activity" EXACT [] +is_obsolete: true +consider: GO:0046033 + +[Term] +id: GO:0009985 +name: obsolete dihydroflavonol(thiole) lyase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:tb] +comment: This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists. +synonym: "dihydroflavonol(thiole) lyase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0009986 +name: cell surface +namespace: cellular_component +alt_id: GO:0009928 +alt_id: GO:0009929 +def: "The external part of the cell wall and/or plasma membrane." [GOC:jl, GOC:mtg_sensu, GOC:sm] +comment: Note that this term is intended to annotate gene products that are attached (integrated or loosely bound) to the plasma membrane or cell wall. +subset: goslim_pir +synonym: "cell associated" EXACT [] +synonym: "cell bound" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0009987 +name: cellular process +namespace: biological_process +alt_id: GO:0008151 +alt_id: GO:0044763 +alt_id: GO:0050875 +def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] +subset: goslim_plant +synonym: "cell growth and/or maintenance" NARROW [] +synonym: "cell physiology" EXACT [] +synonym: "cellular physiological process" EXACT [] +synonym: "single-organism cellular process" RELATED [] +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +created_by: jl +creation_date: 2012-12-11T16:56:55Z + +[Term] +id: GO:0009988 +name: cell-cell recognition +namespace: biological_process +def: "Cell recognition between cells. May involve the formation of specialized cell junctions." [ISBN:0824072820] +is_a: GO:0008037 ! cell recognition + +[Term] +id: GO:0009989 +name: cell-matrix recognition +namespace: biological_process +def: "Cell recognition that involves the interaction of the cell with the extracellular matrix." [ISBN:0824072820] +is_a: GO:0008037 ! cell recognition + +[Term] +id: GO:0009990 +name: contact guidance +namespace: biological_process +def: "Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells." [ISBN:0824072820] +is_a: GO:0009989 ! cell-matrix recognition + +[Term] +id: GO:0009991 +name: response to extracellular stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus." [GOC:go_curators] +is_a: GO:0009605 ! response to external stimulus + +[Term] +id: GO:0009992 +name: cellular water homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of water within a cell." [GOC:dph, GOC:tb] +synonym: "cellular osmoregulation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006884 ! cell volume homeostasis +is_a: GO:0030104 ! water homeostasis +is_a: GO:0055082 ! cellular chemical homeostasis + +[Term] +id: GO:0009994 +name: oocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu] +synonym: "oocyte cell differentiation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0009995 +name: soluble molecule recognition +namespace: biological_process +def: "The recognition of soluble molecules in the environment." [GOC:go_curators] +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0009996 +name: negative regulation of cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from adopting a specific cell fate." [GOC:go_curators] +synonym: "down regulation of cell fate specification" EXACT [] +synonym: "down-regulation of cell fate specification" EXACT [] +synonym: "downregulation of cell fate specification" EXACT [] +synonym: "inhibition of cell fate specification" NARROW [] +synonym: "suppression of cell fate" EXACT [] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0042659 ! regulation of cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001708 ! cell fate specification +relationship: negatively_regulates GO:0001708 ! cell fate specification + +[Term] +id: GO:0009997 +name: negative regulation of cardioblast cell fate specification +namespace: biological_process +alt_id: GO:0042687 +def: "Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +synonym: "down regulation of cardioblast cell fate specification" EXACT [] +synonym: "down-regulation of cardioblast cell fate specification" EXACT [] +synonym: "downregulation of cardioblast cell fate specification" EXACT [] +synonym: "inhibition of cardioblast cell fate specification" NARROW [] +synonym: "suppression of cardioblast cell fate" EXACT [] +is_a: GO:0042686 ! regulation of cardioblast cell fate specification +is_a: GO:0051892 ! negative regulation of cardioblast differentiation +is_a: GO:2000044 ! negative regulation of cardiac cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042685 ! cardioblast cell fate specification +relationship: negatively_regulates GO:0042685 ! cardioblast cell fate specification + +[Term] +id: GO:0009998 +name: negative regulation of retinal cone cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell." [GOC:go_curators] +synonym: "down regulation of retinal cone cell fate specification" EXACT [] +synonym: "down-regulation of retinal cone cell fate specification" EXACT [] +synonym: "downregulation of retinal cone cell fate specification" EXACT [] +synonym: "inhibition of retinal cone cell fate specification" NARROW [] +synonym: "negative regulation of retina cone cell fate specification" EXACT [] +synonym: "suppression of retina cone cell fate" EXACT [] +synonym: "suppression of retinal cone cell fate" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042673 ! regulation of retinal cone cell fate specification +is_a: GO:0060226 ! negative regulation of retinal cone cell fate commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042672 ! retinal cone cell fate specification +relationship: negatively_regulates GO:0042672 ! retinal cone cell fate specification + +[Term] +id: GO:0009999 +name: negative regulation of auditory receptor cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell." [GOC:go_curators] +synonym: "down regulation of auditory receptor cell fate specification" EXACT [] +synonym: "down-regulation of auditory receptor cell fate specification" EXACT [] +synonym: "downregulation of auditory receptor cell fate specification" EXACT [] +synonym: "inhibition of auditory receptor cell fate specification" NARROW [] +synonym: "negative regulation of auditory hair cell fate specification" EXACT [] +synonym: "suppression of auditory receptor cell fate" EXACT [] +synonym: "suppression of hair cell fate" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042669 ! regulation of inner ear auditory receptor cell fate specification +is_a: GO:0045608 ! negative regulation of inner ear auditory receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042667 ! auditory receptor cell fate specification +relationship: negatively_regulates GO:0042667 ! auditory receptor cell fate specification + +[Term] +id: GO:0010001 +name: glial cell differentiation +namespace: biological_process +alt_id: GO:0007404 +alt_id: GO:0043360 +def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] +synonym: "glia cell differentiation" EXACT [] +synonym: "neuroglia differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0042063 ! gliogenesis + +[Term] +id: GO:0010002 +name: cardioblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart] +synonym: "cardioblast cell differentiation" EXACT [] +synonym: "cardiomyocyte generation" RELATED [] +is_a: GO:0035051 ! cardiocyte differentiation +is_a: GO:0048863 ! stem cell differentiation + +[Term] +id: GO:0010004 +name: gastrulation involving germ band extension +namespace: biological_process +def: "A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0001703 ! gastrulation with mouth forming first + +[Term] +id: GO:0010005 +name: cortical microtubule, transverse to long axis +namespace: cellular_component +def: "Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition." [ISBN:0943088399] +is_a: GO:0055028 ! cortical microtubule + +[Term] +id: GO:0010006 +name: Toc complex +namespace: cellular_component +def: "Protein translocon complex at the chloroplast outer membrane." [PMID:10646606] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009707 ! chloroplast outer membrane + +[Term] +id: GO:0010007 +name: magnesium chelatase complex +namespace: cellular_component +def: "A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner." [PMID:11842180] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0010008 +name: endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an endosome." [GOC:mah] +synonym: "endosomal membrane" EXACT [NIF_Subcellular:sao978443756] +xref: NIF_Subcellular:sao978443756 +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0005768 ! endosome + +[Term] +id: GO:0010009 +name: cytoplasmic side of endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the endosome membrane that faces the cytoplasm." [GOC:lr] +synonym: "external leaflet of endosome membrane" EXACT [GOC:ab] +synonym: "external side of endosome membrane" EXACT [] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0010011 +name: auxin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth." [GOC:sm] +synonym: "auxin receptor" NARROW [] +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0010012 +name: steroid 22-alpha hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O." [GOC:tb] +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0010013 +name: N-1-naphthylphthalamic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor." [GOC:sm] +is_a: GO:0008144 ! drug binding +is_a: GO:0033218 ! amide binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding + +[Term] +id: GO:0010014 +name: meristem initiation +namespace: biological_process +def: "Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue." [GOC:sm] +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0009933 ! meristem structural organization + +[Term] +id: GO:0010015 +name: root morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support." [GOC:sm, ISBN:0877797099] +is_a: GO:1905392 ! plant organ morphogenesis +relationship: part_of GO:0048364 ! root development + +[Term] +id: GO:0010016 +name: shoot system morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground." [GOC:sm, ISBN:0877797099] +synonym: "shoot morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048367 ! shoot system development + +[Term] +id: GO:0010017 +name: red or far-red light signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:lr, GOC:mtg_far_red, GOC:sm] +synonym: "phytochrome signaling pathway" BROAD [] +synonym: "red or far red light signaling pathway" EXACT [GOC:bf, GOC:tb] +synonym: "red or far-red light signal transduction" EXACT [GOC:signaling] +synonym: "red or far-red light signalling pathway" EXACT [] +synonym: "red/far red light signaling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +is_a: GO:0071489 ! cellular response to red or far red light + +[Term] +id: GO:0010018 +name: far-red light signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:lr, GOC:mtg_far_red, GOC:sm] +synonym: "far red light signalling pathway" EXACT [] +synonym: "far red signaling pathway" EXACT [GOC:tb] +synonym: "far-red light signal transduction" EXACT [GOC:signaling] +is_a: GO:0010017 ! red or far-red light signaling pathway +is_a: GO:0071490 ! cellular response to far red light + +[Term] +id: GO:0010019 +name: chloroplast-nucleus signaling pathway +namespace: biological_process +def: "The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis." [PMID:8972595] +synonym: "chloroplast-nucleus signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0010020 +name: chloroplast fission +namespace: biological_process +def: "The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis." [GOC:lr] +synonym: "chloroplast division" EXACT [] +is_a: GO:0009658 ! chloroplast organization +is_a: GO:0043572 ! plastid fission + +[Term] +id: GO:0010021 +name: amylopectin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages." [ISBN:0943088399] +synonym: "amylopectin anabolism" EXACT [] +synonym: "amylopectin biosynthesis" EXACT [] +synonym: "amylopectin formation" EXACT [] +synonym: "amylopectin synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:2000896 ! amylopectin metabolic process + +[Term] +id: GO:0010022 +name: meristem determinacy +namespace: biological_process +def: "The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate)." [GOC:lr] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0010073 ! meristem maintenance + +[Term] +id: GO:0010023 +name: proanthocyanidin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of proanthocyanidin." [GOC:lm] +synonym: "proanthocyanidin anabolism" EXACT [] +synonym: "proanthocyanidin biosynthesis" EXACT [] +synonym: "proanthocyanidin formation" EXACT [] +synonym: "proanthocyanidin synthesis" EXACT [] +xref: MetaCyc:PWY-641 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0010024 +name: phytochromobilin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha." [PMID:11402195] +synonym: "phytochromobilin anabolism" EXACT [] +synonym: "phytochromobilin biosynthesis" EXACT [] +synonym: "phytochromobilin formation" EXACT [] +synonym: "phytochromobilin synthesis" EXACT [] +is_a: GO:0033014 ! tetrapyrrole biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0051202 ! phytochromobilin metabolic process + +[Term] +id: GO:0010025 +name: wax biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids." [ISBN:0943088399] +synonym: "wax anabolism" EXACT [] +synonym: "wax biosynthesis" EXACT [] +synonym: "wax formation" EXACT [] +synonym: "wax synthesis" EXACT [] +xref: MetaCyc:PWY-282 +is_a: GO:0010166 ! wax metabolic process +is_a: GO:1901570 ! fatty acid derivative biosynthetic process + +[Term] +id: GO:0010026 +name: trichome differentiation +namespace: biological_process +alt_id: GO:0048271 +def: "The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, PMID:9367433] +synonym: "trichome cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0090558 ! plant epidermis development + +[Term] +id: GO:0010027 +name: thylakoid membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane." [GOC:dph, GOC:jl, GOC:mah, GOC:tb] +comment: See also the cellular component term 'thylakoid membrane ; GO:0042651'. +synonym: "thylakoid membrane organisation" EXACT [] +synonym: "thylakoid membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009668 ! plastid membrane organization + +[Term] +id: GO:0010028 +name: xanthophyll cycle +namespace: biological_process +def: "A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II." [ISBN:0122146743] +xref: MetaCyc:PWY-1141 +xref: Wikipedia:Xanthophyll#Xanthophyll_cycle +is_a: GO:0016122 ! xanthophyll metabolic process + +[Term] +id: GO:0010029 +name: regulation of seed germination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of seed germination." [GOC:sm] +is_a: GO:1900140 ! regulation of seedling development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009845 ! seed germination +relationship: regulates GO:0009845 ! seed germination + +[Term] +id: GO:0010030 +name: positive regulation of seed germination +namespace: biological_process +def: "Any process that activates or increase the rate of seed germination." [GOC:sm] +synonym: "activation of seed germination" NARROW [] +synonym: "stimulation of seed germination" NARROW [] +synonym: "up regulation of seed germination" EXACT [] +synonym: "up-regulation of seed germination" EXACT [] +synonym: "upregulation of seed germination" EXACT [] +is_a: GO:0010029 ! regulation of seed germination +is_a: GO:0048582 ! positive regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009845 ! seed germination +relationship: positively_regulates GO:0009845 ! seed germination + +[Term] +id: GO:0010031 +name: circumnutation +namespace: biological_process +def: "The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth." [GOC:mtg_MIT_16mar07, ISBN:0192801023] +is_a: GO:0050879 ! multicellular organismal movement + +[Term] +id: GO:0010032 +name: meiotic chromosome condensation +namespace: biological_process +def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401] +synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030261 ! chromosome condensation +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +intersection_of: GO:0030261 ! chromosome condensation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0010033 +name: response to organic substance +namespace: biological_process +alt_id: GO:1990367 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm, PMID:23356676] +synonym: "process resulting in tolerance to organic substance" NARROW [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0010034 +name: response to acetate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010033 ! response to organic substance +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010035 +name: response to inorganic substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0010036 +name: response to boron-containing substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus." [GOC:sm] +synonym: "response to boron" EXACT [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0010037 +name: response to carbon dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus." [GOC:sm] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0072347 ! response to anesthetic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010038 +name: response to metal ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] +synonym: "heavy metal sensitivity/resistance" RELATED [] +synonym: "response to heavy metal" NARROW [] +synonym: "response to metal" EXACT [] +is_a: GO:0010035 ! response to inorganic substance + +[Term] +id: GO:0010039 +name: response to iron ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus." [GOC:sm] +synonym: "response to iron" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010040 +name: response to iron(II) ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus." [GOC:sm] +synonym: "response to iron(II)" EXACT [] +is_a: GO:0010039 ! response to iron ion + +[Term] +id: GO:0010041 +name: response to iron(III) ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus." [GOC:sm] +synonym: "response to iron(III)" EXACT [] +is_a: GO:0010039 ! response to iron ion + +[Term] +id: GO:0010042 +name: response to manganese ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus." [GOC:sm] +synonym: "response to manganese" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010043 +name: response to zinc ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus." [GOC:sm] +synonym: "response to zinc" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010044 +name: response to aluminum ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus." [GOC:sm] +synonym: "response to aluminium ion" EXACT [] +synonym: "response to aluminum" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010045 +name: response to nickel cation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus." [GOC:sm] +synonym: "response to nickel" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010046 +name: response to mycotoxin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi." [GOC:sm] +is_a: GO:0009636 ! response to toxic substance + +[Term] +id: GO:0010047 +name: fruit dehiscence +namespace: biological_process +def: "The process leading to the spontaneous opening of the fruit permitting the escape of seeds." [GOC:tb, ISBN:0471245208] +is_a: GO:0009900 ! dehiscence + +[Term] +id: GO:0010048 +name: vernalization response +namespace: biological_process +def: "The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures." [GOC:tair_curators, ISBN:0521591392] +is_a: GO:0009409 ! response to cold + +[Term] +id: GO:0010049 +name: acquisition of plant reproductive competence +namespace: biological_process +def: "The process in which a plant acquires the ability to respond to a floral inductive signal." [GOC:tair_curators] +synonym: "acquisition of reproductive competence" BROAD [] +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0010050 +name: vegetative phase change +namespace: biological_process +def: "Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development." [GOC:tb] +is_a: GO:0009791 ! post-embryonic development + +[Term] +id: GO:0010051 +name: xylem and phloem pattern formation +namespace: biological_process +def: "The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tb] +synonym: "vascular tissue pattern formation" EXACT [] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0010052 +name: guard cell differentiation +namespace: biological_process +def: "The process in which a guard mother cell acquires the specialized features of a guard cell." [GOC:expert_db, GOC:tb] +synonym: "stomatal cell differentiation" RELATED [] +is_a: GO:0090627 ! plant epidermal cell differentiation +relationship: part_of GO:0010103 ! stomatal complex morphogenesis + +[Term] +id: GO:0010053 +name: root epidermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast." [GOC:tb] +is_a: GO:0090627 ! plant epidermal cell differentiation +relationship: part_of GO:0010015 ! root morphogenesis +relationship: part_of GO:0090558 ! plant epidermis development + +[Term] +id: GO:0010054 +name: trichoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair." [GOC:tb] +synonym: "trichoblast cell differentiation" EXACT [] +is_a: GO:0010053 ! root epidermal cell differentiation + +[Term] +id: GO:0010055 +name: atrichoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair." [GOC:tb] +is_a: GO:0010053 ! root epidermal cell differentiation + +[Term] +id: GO:0010056 +name: atrichoblast fate specification +namespace: biological_process +def: "The process involved in the specification of an atrichoblast." [GOC:tb] +is_a: GO:0090628 ! plant epidermal cell fate specification +relationship: part_of GO:0010055 ! atrichoblast differentiation + +[Term] +id: GO:0010057 +name: trichoblast fate specification +namespace: biological_process +def: "The process involved in the specification of a trichoblast." [GOC:tb] +is_a: GO:0090628 ! plant epidermal cell fate specification +relationship: part_of GO:0010054 ! trichoblast differentiation + +[Term] +id: GO:0010058 +name: regulation of atrichoblast fate specification +namespace: biological_process +def: "Any process that modulates atrichoblast fate specification." [GOC:tb] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:1903888 ! regulation of plant epidermal cell differentiation +is_a: GO:2000067 ! regulation of root morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010056 ! atrichoblast fate specification +relationship: regulates GO:0010056 ! atrichoblast fate specification + +[Term] +id: GO:0010059 +name: positive regulation of atrichoblast fate specification +namespace: biological_process +def: "Any process that induces or promotes atrichoblast fate specification." [GOC:tb] +synonym: "activation of atrichoblast fate" NARROW [] +synonym: "stimulation of atrichoblast fate" NARROW [] +synonym: "up regulation of atrichoblast fate" EXACT [] +synonym: "up-regulation of atrichoblast fate" EXACT [] +synonym: "upregulation of atrichoblast fate" EXACT [] +is_a: GO:0010058 ! regulation of atrichoblast fate specification +is_a: GO:0042660 ! positive regulation of cell fate specification +is_a: GO:1903890 ! positive regulation of plant epidermal cell differentiation +is_a: GO:1905423 ! positive regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010056 ! atrichoblast fate specification +relationship: positively_regulates GO:0010056 ! atrichoblast fate specification + +[Term] +id: GO:0010060 +name: negative regulation of atrichoblast fate specification +namespace: biological_process +def: "Any process that suppresses atrichoblast fate specification." [GOC:tb] +synonym: "down regulation of atrichoblast fate" EXACT [] +synonym: "down-regulation of atrichoblast fate" EXACT [] +synonym: "downregulation of atrichoblast fate" EXACT [] +synonym: "inhibition of atrichoblast fate" NARROW [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0010058 ! regulation of atrichoblast fate specification +is_a: GO:1903889 ! negative regulation of plant epidermal cell differentiation +is_a: GO:1905422 ! negative regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010056 ! atrichoblast fate specification +relationship: negatively_regulates GO:0010056 ! atrichoblast fate specification + +[Term] +id: GO:0010061 +name: regulation of trichoblast fate specification +namespace: biological_process +def: "Any process that modulates trichoblast fate specification." [GOC:tb] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:1903888 ! regulation of plant epidermal cell differentiation +is_a: GO:2000067 ! regulation of root morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010057 ! trichoblast fate specification +relationship: regulates GO:0010057 ! trichoblast fate specification + +[Term] +id: GO:0010062 +name: negative regulation of trichoblast fate specification +namespace: biological_process +def: "Any process that suppresses trichoblast fate specification." [GOC:tb] +synonym: "down regulation of trichoblast fate" EXACT [] +synonym: "down-regulation of trichoblast fate" EXACT [] +synonym: "downregulation of trichoblast fate" EXACT [] +synonym: "inhibition of trichoblast fate" NARROW [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0010061 ! regulation of trichoblast fate specification +is_a: GO:1903889 ! negative regulation of plant epidermal cell differentiation +is_a: GO:1905422 ! negative regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010057 ! trichoblast fate specification +relationship: negatively_regulates GO:0010057 ! trichoblast fate specification + +[Term] +id: GO:0010063 +name: positive regulation of trichoblast fate specification +namespace: biological_process +def: "Any process that induces or promotes trichoblast fate specification." [GOC:tb] +synonym: "activation of trichoblast fate" NARROW [] +synonym: "stimulation of trichoblast fate" NARROW [] +synonym: "up regulation of trichoblast fate" EXACT [] +synonym: "up-regulation of trichoblast fate" EXACT [] +synonym: "upregulation of trichoblast fate" EXACT [] +is_a: GO:0010061 ! regulation of trichoblast fate specification +is_a: GO:0042660 ! positive regulation of cell fate specification +is_a: GO:1903890 ! positive regulation of plant epidermal cell differentiation +is_a: GO:1905423 ! positive regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010057 ! trichoblast fate specification +relationship: positively_regulates GO:0010057 ! trichoblast fate specification + +[Term] +id: GO:0010064 +name: embryonic shoot morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of embryonic shoot are generated and organized." [GOC:tb] +synonym: "primary shoot system morphogenesis" EXACT [] +is_a: GO:0010016 ! shoot system morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0010065 +name: primary meristem tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium." [GOC:tb, ISBN:0471245208] +synonym: "primary meristem histogenesis" EXACT [] +is_a: GO:0048508 ! embryonic meristem development + +[Term] +id: GO:0010066 +name: ground meristem histogenesis +namespace: biological_process +def: "The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues." [GOC:tb, ISBN:0471245208] +is_a: GO:0010065 ! primary meristem tissue development + +[Term] +id: GO:0010067 +name: procambium histogenesis +namespace: biological_process +def: "The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue." [GOC:tb, ISBN:0471245208] +is_a: GO:0010065 ! primary meristem tissue development + +[Term] +id: GO:0010068 +name: protoderm histogenesis +namespace: biological_process +def: "The formation of the primary meristem or meristematic tissue that gives rise to the epidermis." [GOC:tb, ISBN:0471245208] +is_a: GO:0010065 ! primary meristem tissue development + +[Term] +id: GO:0010069 +name: zygote asymmetric cytokinesis in embryo sac +namespace: biological_process +def: "The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tb, ISBN:0865427429] +is_a: GO:0000281 ! mitotic cytokinesis +is_a: GO:0010070 ! zygote asymmetric cell division +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0009793 ! embryo development ending in seed dormancy + +[Term] +id: GO:0010070 +name: zygote asymmetric cell division +namespace: biological_process +def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] +synonym: "zygote asymmetric cytokinesis" RELATED [] +is_a: GO:0008356 ! asymmetric cell division + +[Term] +id: GO:0010071 +name: root meristem specification +namespace: biological_process +def: "The specification of a meristem which will give rise to a primary or lateral root." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090421 ! embryonic meristem initiation +relationship: part_of GO:0010015 ! root morphogenesis +relationship: part_of GO:0048508 ! embryonic meristem development + +[Term] +id: GO:0010072 +name: primary shoot apical meristem specification +namespace: biological_process +def: "The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers." [GOC:ascb_2009, GOC:dph, GOC:tair_curators, GOC:tb] +synonym: "embryo shoot apical meristem specification" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090421 ! embryonic meristem initiation +relationship: part_of GO:0010016 ! shoot system morphogenesis +relationship: part_of GO:0048508 ! embryonic meristem development + +[Term] +id: GO:0010073 +name: meristem maintenance +namespace: biological_process +def: "Any process involved in maintaining the identity, size and shape of a meristem." [GOC:tb] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0048507 ! meristem development + +[Term] +id: GO:0010074 +name: maintenance of meristem identity +namespace: biological_process +alt_id: GO:0032503 +def: "The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:tb] +synonym: "maintenance of meristem cell identity" EXACT [] +synonym: "meristem cell maintenance" EXACT [] +is_a: GO:0019827 ! stem cell population maintenance +relationship: part_of GO:0010073 ! meristem maintenance + +[Term] +id: GO:0010075 +name: regulation of meristem growth +namespace: biological_process +def: "Any process involved in maintaining the size and shape of a meristem." [GOC:tb] +synonym: "regulation of meristem size" EXACT [GOC:tb] +is_a: GO:0048509 ! regulation of meristem development +is_a: GO:0048638 ! regulation of developmental growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035266 ! meristem growth +relationship: part_of GO:0010073 ! meristem maintenance +relationship: regulates GO:0035266 ! meristem growth + +[Term] +id: GO:0010076 +name: maintenance of floral meristem identity +namespace: biological_process +def: "The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:dph, GOC:tb] +is_a: GO:0010074 ! maintenance of meristem identity + +[Term] +id: GO:0010077 +name: maintenance of inflorescence meristem identity +namespace: biological_process +def: "The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:dph, GOC:tb] +is_a: GO:0010074 ! maintenance of meristem identity + +[Term] +id: GO:0010078 +name: maintenance of root meristem identity +namespace: biological_process +def: "The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:dph, GOC:tb] +is_a: GO:0010074 ! maintenance of meristem identity +relationship: part_of GO:0010015 ! root morphogenesis + +[Term] +id: GO:0010079 +name: maintenance of vegetative meristem identity +namespace: biological_process +def: "The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:dph, GOC:tb] +is_a: GO:0010074 ! maintenance of meristem identity + +[Term] +id: GO:0010080 +name: regulation of floral meristem growth +namespace: biological_process +def: "Any process involved in maintaining the size and shape of a floral meristem." [GOC:tb] +synonym: "regulation of floral meristem size" EXACT [] +is_a: GO:0009909 ! regulation of flower development +is_a: GO:0010075 ! regulation of meristem growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010451 ! floral meristem growth +relationship: regulates GO:0010451 ! floral meristem growth + +[Term] +id: GO:0010081 +name: regulation of inflorescence meristem growth +namespace: biological_process +def: "Any process involved in maintaining the size and shape of an inflorescence meristem." [GOC:tb] +synonym: "regulation of inflorescence meristem size" EXACT [GOC:tb] +is_a: GO:0010075 ! regulation of meristem growth +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0048831 ! regulation of shoot system development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010450 ! inflorescence meristem growth +relationship: regulates GO:0010450 ! inflorescence meristem growth + +[Term] +id: GO:0010082 +name: regulation of root meristem growth +namespace: biological_process +def: "Any process involved in maintaining the size and shape of a root meristem." [GOC:tb] +synonym: "regulation of root meristem size" EXACT [GOC:tb] +is_a: GO:0010075 ! regulation of meristem growth +is_a: GO:2000280 ! regulation of root development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010449 ! root meristem growth +relationship: part_of GO:0010015 ! root morphogenesis +relationship: regulates GO:0010449 ! root meristem growth + +[Term] +id: GO:0010083 +name: regulation of vegetative meristem growth +namespace: biological_process +def: "Any process involved in maintaining the size and shape of a vegetative meristem." [GOC:tb] +synonym: "regulation of vegetative meristem size" EXACT [GOC:tb] +is_a: GO:0010075 ! regulation of meristem growth +is_a: GO:0048831 ! regulation of shoot system development +is_a: GO:1905613 ! regulation of developmental vegetative growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010448 ! vegetative meristem growth +relationship: regulates GO:0010448 ! vegetative meristem growth + +[Term] +id: GO:0010084 +name: specification of animal organ axis polarity +namespace: biological_process +def: "The process in which the polarity of an animal organ axis is specified." [GOC:tb] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:0009887 ! animal organ morphogenesis + +[Term] +id: GO:0010085 +name: polarity specification of proximal/distal axis +namespace: biological_process +def: "Any process resulting in the establishment of polarity along the proximal/distal axis." [GOC:tb] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:0009946 ! proximal/distal axis specification + +[Term] +id: GO:0010086 +name: embryonic root morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the embryonic root are generated and organized." [GOC:tb] +is_a: GO:0010015 ! root morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0010087 +name: phloem or xylem histogenesis +namespace: biological_process +def: "The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tb] +synonym: "vascular tissue development" BROAD [] +synonym: "vascular tissue histogenesis" EXACT [] +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0010088 +name: phloem development +namespace: biological_process +def: "The formation of the principal food-conducting tissue of a vascular plant." [GOC:tb, ISBN:0471245208] +synonym: "phloem histogenesis" EXACT [GOC:tb] +is_a: GO:0010087 ! phloem or xylem histogenesis + +[Term] +id: GO:0010089 +name: xylem development +namespace: biological_process +def: "The formation of the principal water-conducting tissue of a vascular plant." [GOC:tb, ISBN:0471245208] +synonym: "xylem histogenesis" EXACT [GOC:tb] +is_a: GO:0010087 ! phloem or xylem histogenesis + +[Term] +id: GO:0010090 +name: trichome morphogenesis +namespace: biological_process +alt_id: GO:0048272 +def: "The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tair_curators] +synonym: "trichome cell morphogenesis during differentiation" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0010026 ! trichome differentiation +relationship: part_of GO:0090626 ! plant epidermis morphogenesis + +[Term] +id: GO:0010091 +name: trichome branching +namespace: biological_process +alt_id: GO:0048274 +def: "Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana." [GOC:mtg_sensu, GOC:tair_curators] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0010090 ! trichome morphogenesis + +[Term] +id: GO:0010092 +name: specification of animal organ identity +namespace: biological_process +def: "The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0048645 ! animal organ formation + +[Term] +id: GO:0010093 +name: specification of floral organ identity +namespace: biological_process +def: "The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090701 ! specification of plant organ identity +relationship: part_of GO:0048449 ! floral organ formation + +[Term] +id: GO:0010094 +name: specification of carpel identity +namespace: biological_process +def: "The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators] +is_a: GO:0010093 ! specification of floral organ identity +relationship: part_of GO:0048462 ! carpel formation + +[Term] +id: GO:0010095 +name: specification of petal identity +namespace: biological_process +def: "The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators] +is_a: GO:0010093 ! specification of floral organ identity +relationship: part_of GO:0048451 ! petal formation + +[Term] +id: GO:0010096 +name: specification of sepal identity +namespace: biological_process +def: "The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators] +is_a: GO:0010093 ! specification of floral organ identity +relationship: part_of GO:0048453 ! sepal formation + +[Term] +id: GO:0010097 +name: specification of stamen identity +namespace: biological_process +def: "The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators] +is_a: GO:0010093 ! specification of floral organ identity +relationship: part_of GO:0048455 ! stamen formation + +[Term] +id: GO:0010098 +name: suspensor development +namespace: biological_process +def: "The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm." [GOC:tb, ISBN:0471245208] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0010099 +name: regulation of photomorphogenesis +namespace: biological_process +def: "Any process that modulates the rate or extent of photomorphogenesis." [GOC:tb] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:2000030 ! regulation of response to red or far red light +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009640 ! photomorphogenesis +relationship: regulates GO:0009640 ! photomorphogenesis + +[Term] +id: GO:0010100 +name: negative regulation of photomorphogenesis +namespace: biological_process +def: "Any process that stops, reduces or prevents photomorphogenesis." [GOC:tb] +synonym: "down regulation of photomorphogenesis" EXACT [] +synonym: "down-regulation of photomorphogenesis" EXACT [] +synonym: "downregulation of photomorphogenesis" EXACT [] +synonym: "inhibition of photomorphogenesis" NARROW [] +is_a: GO:0010099 ! regulation of photomorphogenesis +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009640 ! photomorphogenesis +relationship: negatively_regulates GO:0009640 ! photomorphogenesis + +[Term] +id: GO:0010101 +name: post-embryonic root morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed." [GOC:tb] +is_a: GO:0010015 ! root morphogenesis +is_a: GO:0090697 ! post-embryonic plant organ morphogenesis +relationship: part_of GO:0048528 ! post-embryonic root development + +[Term] +id: GO:0010102 +name: lateral root morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper." [GOC:tair_curators] +is_a: GO:0010101 ! post-embryonic root morphogenesis +relationship: part_of GO:0048527 ! lateral root development + +[Term] +id: GO:0010103 +name: stomatal complex morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells." [GOC:tair_curators] +is_a: GO:0090626 ! plant epidermis morphogenesis +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0010016 ! shoot system morphogenesis +relationship: part_of GO:0010374 ! stomatal complex development + +[Term] +id: GO:0010104 +name: regulation of ethylene-activated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction." [GOC:tb] +synonym: "regulation of ethene mediated signaling pathway" EXACT [] +synonym: "regulation of ethene mediated signalling pathway" EXACT [] +synonym: "regulation of ethylene mediated signaling pathway" RELATED [] +synonym: "regulation of ethylene mediated signalling pathway" EXACT [] +is_a: GO:0070297 ! regulation of phosphorelay signal transduction system +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009873 ! ethylene-activated signaling pathway +relationship: regulates GO:0009873 ! ethylene-activated signaling pathway + +[Term] +id: GO:0010105 +name: negative regulation of ethylene-activated signaling pathway +namespace: biological_process +def: "Any process that stops or prevents ethylene (ethene) signal transduction." [GOC:tb] +synonym: "down regulation of ethylene mediated signaling pathway" EXACT [] +synonym: "down-regulation of ethylene mediated signaling pathway" EXACT [] +synonym: "downregulation of ethylene mediated signaling pathway" EXACT [] +synonym: "inhibition of ethylene mediated signaling pathway" NARROW [] +synonym: "negative regulation of ethene mediated signaling pathway" EXACT [] +synonym: "negative regulation of ethene mediated signalling pathway" EXACT [] +synonym: "negative regulation of ethylene mediated signaling pathway" RELATED [] +synonym: "negative regulation of ethylene mediated signalling pathway" EXACT [] +is_a: GO:0010104 ! regulation of ethylene-activated signaling pathway +is_a: GO:0070298 ! negative regulation of phosphorelay signal transduction system +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009873 ! ethylene-activated signaling pathway +relationship: negatively_regulates GO:0009873 ! ethylene-activated signaling pathway + +[Term] +id: GO:0010106 +name: cellular response to iron ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions." [GOC:mg] +is_a: GO:0009267 ! cellular response to starvation +relationship: part_of GO:0006879 ! cellular iron ion homeostasis + +[Term] +id: GO:0010108 +name: detection of glutamine +namespace: biological_process +def: "The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "glutamine detection" EXACT [] +synonym: "glutamine perception" RELATED [] +synonym: "glutamine sensing" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0010109 +name: regulation of photosynthesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of photosynthesis." [GOC:sm] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015979 ! photosynthesis +relationship: regulates GO:0015979 ! photosynthesis + +[Term] +id: GO:0010110 +name: regulation of photosynthesis, dark reaction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of photosynthesis dark reaction." [GOC:sm] +is_a: GO:0010109 ! regulation of photosynthesis +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019685 ! photosynthesis, dark reaction +relationship: regulates GO:0019685 ! photosynthesis, dark reaction + +[Term] +id: GO:0010111 +name: glyoxysome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway." [GOC:tb] +synonym: "glyoxysome organisation" EXACT [] +synonym: "glyoxysome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007031 ! peroxisome organization +is_a: GO:0009657 ! plastid organization + +[Term] +id: GO:0010112 +name: regulation of systemic acquired resistance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of systemic acquired resistance." [GOC:sm] +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009627 ! systemic acquired resistance +relationship: regulates GO:0009627 ! systemic acquired resistance + +[Term] +id: GO:0010113 +name: negative regulation of systemic acquired resistance +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance." [GOC:sm] +synonym: "down regulation of systemic acquired resistance" EXACT [] +synonym: "down-regulation of systemic acquired resistance" EXACT [] +synonym: "downregulation of systemic acquired resistance" EXACT [] +synonym: "inhibition of systemic acquired resistance" NARROW [] +is_a: GO:0010112 ! regulation of systemic acquired resistance +is_a: GO:0045824 ! negative regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009627 ! systemic acquired resistance +relationship: negatively_regulates GO:0009627 ! systemic acquired resistance + +[Term] +id: GO:0010114 +name: response to red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mtg_far_red, GOC:sm] +synonym: "response to red light stimulus" EXACT [] +is_a: GO:0009639 ! response to red or far red light + +[Term] +id: GO:0010115 +name: regulation of abscisic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid." [GOC:sm] +synonym: "regulation of abscisic acid anabolism" EXACT [] +synonym: "regulation of abscisic acid biosynthesis" EXACT [] +synonym: "regulation of abscisic acid formation" EXACT [] +synonym: "regulation of abscisic acid synthesis" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009688 ! abscisic acid biosynthetic process +relationship: regulates GO:0009688 ! abscisic acid biosynthetic process + +[Term] +id: GO:0010116 +name: positive regulation of abscisic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid." [GOC:sm] +synonym: "activation of abscisic acid biosynthetic process" NARROW [] +synonym: "positive regulation of abscisic acid anabolism" EXACT [] +synonym: "positive regulation of abscisic acid biosynthesis" EXACT [] +synonym: "positive regulation of abscisic acid formation" EXACT [] +synonym: "positive regulation of abscisic acid synthesis" EXACT [] +synonym: "stimulation of abscisic acid biosynthetic process" NARROW [] +synonym: "up regulation of abscisic acid biosynthetic process" EXACT [] +synonym: "up-regulation of abscisic acid biosynthetic process" EXACT [] +synonym: "upregulation of abscisic acid biosynthetic process" EXACT [] +is_a: GO:0010115 ! regulation of abscisic acid biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009688 ! abscisic acid biosynthetic process +relationship: positively_regulates GO:0009688 ! abscisic acid biosynthetic process + +[Term] +id: GO:0010117 +name: photoprotection +namespace: biological_process +def: "Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis." [GOC:mg] +is_a: GO:0009416 ! response to light stimulus + +[Term] +id: GO:0010118 +name: stomatal movement +namespace: biological_process +def: "The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata)." [GOC:sm] +subset: goslim_pir +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0010119 +name: regulation of stomatal movement +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stomatal movement." [GOC:sm] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010118 ! stomatal movement +relationship: regulates GO:0010118 ! stomatal movement + +[Term] +id: GO:0010120 +name: camalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin." [GOC:pz] +synonym: "camalexin anabolism" EXACT [] +synonym: "camalexin biosynthesis" EXACT [] +synonym: "camalexin formation" EXACT [] +synonym: "camalexin synthesis" EXACT [] +xref: MetaCyc:CAMALEXIN-SYN +is_a: GO:0009700 ! indole phytoalexin biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0052317 ! camalexin metabolic process + +[Term] +id: GO:0010121 +name: arginine catabolic process to proline via ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine." [GOC:pz] +synonym: "arginine breakdown to proline via ornithine" EXACT [] +synonym: "arginine degradation to proline via ornithine" EXACT [] +xref: MetaCyc:ARGORNPROST-PWY +is_a: GO:0019493 ! arginine catabolic process to proline + +[Term] +id: GO:0010122 +name: arginine catabolic process to alanine via ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine." [GOC:pz] +synonym: "arginine breakdown to alanine via ornithine" EXACT [] +synonym: "arginine degradation to alanine via ornithine" EXACT [] +xref: MetaCyc:ARGORNPROST-PWY +is_a: GO:0006522 ! alanine metabolic process +is_a: GO:0006527 ! arginine catabolic process + +[Term] +id: GO:0010123 +name: acetate catabolic process to butyrate, ethanol, acetone and butanol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol." [GOC:pz] +synonym: "acetate fermentation to butyrate, ethanol, acetone and butanol" EXACT [] +xref: MetaCyc:CENTFERM-PWY +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0019605 ! butyrate metabolic process +is_a: GO:0019654 ! acetate fermentation +is_a: GO:0043443 ! acetone metabolic process +is_a: GO:0045733 ! acetate catabolic process +is_a: GO:0071270 ! 1-butanol metabolic process + +[Term] +id: GO:0010124 +name: phenylacetate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenylacetate." [GOC:pz] +synonym: "phenylacetate breakdown" EXACT [] +synonym: "phenylacetate catabolism" EXACT [] +synonym: "phenylacetate degradation" EXACT [] +xref: MetaCyc:PWY0-321 +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0009852 ! auxin catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0010125 +name: mycothiol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione." [GOC:pz] +synonym: "mycothiol anabolism" EXACT [] +synonym: "mycothiol biosynthesis" EXACT [] +synonym: "mycothiol formation" EXACT [] +synonym: "mycothiol synthesis" EXACT [] +xref: MetaCyc:PWY1G-0 +is_a: GO:0010126 ! mycothiol metabolic process +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0010126 +name: mycothiol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione." [GOC:pz] +synonym: "mycothiol metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0010127 +name: mycothiol-dependent detoxification +namespace: biological_process +def: "The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell." [GOC:pz] +synonym: "mycothiol-dependent detoxification of alkylating agent" NARROW [] +xref: MetaCyc:PWY1G-1 +xref: MetaCyc:PWY1G-170 +is_a: GO:0098754 ! detoxification + +[Term] +id: GO:0010128 +name: benzoate catabolic process via CoA ligation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway." [GOC:pz] +synonym: "anaerobic benzoate breakdown" EXACT [] +synonym: "anaerobic benzoate catabolic process" EXACT [] +synonym: "anaerobic benzoate catabolism" EXACT [] +synonym: "anaerobic benzoate degradation" EXACT [] +xref: MetaCyc:PWY-283 +is_a: GO:0018875 ! anaerobic benzoate metabolic process +is_a: GO:0043639 ! benzoate catabolic process + +[Term] +id: GO:0010129 +name: anaerobic cyclohexane-1-carboxylate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen." [GOC:pz] +synonym: "anaerobic cyclohexane-1-carboxylate breakdown" EXACT [] +synonym: "anaerobic cyclohexane-1-carboxylate catabolism" EXACT [] +synonym: "anaerobic cyclohexane-1-carboxylate degradation" EXACT [] +xref: MetaCyc:PWY-301 +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process + +[Term] +id: GO:0010130 +name: anaerobic ethylbenzene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen." [GOC:pz] +synonym: "anaerobic ethylbenzene breakdown" EXACT [] +synonym: "anaerobic ethylbenzene catabolism" EXACT [] +synonym: "anaerobic ethylbenzene degradation" EXACT [] +xref: MetaCyc:PWY-481 +is_a: GO:0018913 ! anaerobic ethylbenzene metabolic process + +[Term] +id: GO:0010131 +name: obsolete sucrose catabolic process, using invertase or sucrose synthase +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase." [GOC:pz] +comment: This term was made obsolete because it describes two different routes of sucrose catabolism, both of which are represented by molecular functions. +synonym: "sucrose breakdown, using invertase or sucrose synthase" EXACT [] +synonym: "sucrose catabolic process, using invertase or sucrose synthase" EXACT [] +synonym: "sucrose catabolism, using invertase or sucrose synthase" EXACT [] +synonym: "sucrose degradation, using invertase or sucrose synthase" EXACT [] +xref: MetaCyc:PWY-3801 +xref: MetaCyc:PWY-621 +is_obsolete: true +consider: GO:0004564 +consider: GO:0005987 +consider: GO:0016157 + +[Term] +id: GO:0010132 +name: dhurrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound." [GOC:pz] +synonym: "dhurrin anabolism" EXACT [] +synonym: "dhurrin biosynthesis" EXACT [] +synonym: "dhurrin formation" EXACT [] +synonym: "dhurrin synthesis" EXACT [] +xref: MetaCyc:PWY-861 +is_a: GO:0019756 ! cyanogenic glycoside biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process + +[Term] +id: GO:0010133 +name: proline catabolic process to glutamate +namespace: biological_process +alt_id: GO:0019494 +def: "The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate." [GOC:pz] +synonym: "proline breakdown to glutamate" EXACT [] +synonym: "proline degradation to glutamate" EXACT [] +synonym: "proline oxidation" RELATED [] +xref: MetaCyc:PROUT-PWY +xref: MetaCyc:PWY-4561 +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0006562 ! proline catabolic process + +[Term] +id: GO:0010134 +name: sulfate assimilation via adenylyl sulfate reduction +namespace: biological_process +def: "The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase." [EC:1.8.99.2] +synonym: "sulphate assimilation via adenylyl sulphate reduction" EXACT [] +xref: MetaCyc:SULFMETII-PWY +is_a: GO:0000103 ! sulfate assimilation +is_a: GO:0019419 ! sulfate reduction + +[Term] +id: GO:0010135 +name: ureide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants." [GOC:pz] +synonym: "ureide metabolism" EXACT [] +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0010136 +name: ureide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium." [GOC:pz] +synonym: "ureide breakdown" EXACT [] +synonym: "ureide catabolism" EXACT [] +synonym: "ureide degradation" EXACT [] +xref: MetaCyc:URDEGR-PWY +is_a: GO:0010135 ! ureide metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process + +[Term] +id: GO:0010137 +name: ureide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots." [GOC:pz] +synonym: "ureide anabolism" EXACT [] +synonym: "ureide biosynthesis" EXACT [] +synonym: "ureide formation" EXACT [] +synonym: "ureide synthesis" EXACT [] +xref: MetaCyc:URSIN-PWY +is_a: GO:0010135 ! ureide metabolic process +is_a: GO:0043604 ! amide biosynthetic process + +[Term] +id: GO:0010138 +name: pyrimidine ribonucleotide salvage +namespace: biological_process +def: "The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis." [GOC:pz] +xref: MetaCyc:PWY0-163 +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0032262 ! pyrimidine nucleotide salvage + +[Term] +id: GO:0010139 +name: pyrimidine deoxyribonucleotide salvage +namespace: biological_process +def: "The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis." [GOC:pz] +xref: MetaCyc:PWY0-181 +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0032262 ! pyrimidine nucleotide salvage + +[Term] +id: GO:0010140 +name: obsolete adenine, hypoxanthine and their nucleoside salvage +namespace: biological_process +def: "OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis." [GOC:pz] +comment: This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology. +synonym: "adenine, hypoxanthine and their nucleoside salvage" EXACT [] +is_obsolete: true +consider: GO:0006168 +consider: GO:0006169 +consider: GO:0006190 +consider: GO:0043103 + +[Term] +id: GO:0010141 +name: obsolete guanine, xanthine and their nucleoside salvage +namespace: biological_process +def: "OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis." [GOC:pz] +comment: This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology. +synonym: "guanine, xanthine and their nucleoside salvage" EXACT [] +is_obsolete: true +consider: GO:0006178 +consider: GO:0006179 +consider: GO:0006190 +consider: GO:0043103 + +[Term] +id: GO:0010142 +name: farnesyl diphosphate biosynthetic process, mevalonate pathway +namespace: biological_process +def: "The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols." [GOC:pz, MetaCyc:PWY-922] +synonym: "Ac-MVA pathway" NARROW [PMID:14517367] +synonym: "acetate-mevalonate pathway" NARROW [PMID:14517367] +synonym: "farnesyl diphosphate anabolism, mevalonate pathway" EXACT [] +synonym: "farnesyl diphosphate formation, mevalonate pathway" EXACT [] +synonym: "farnesyl diphosphate synthesis, mevalonate pathway" EXACT [] +synonym: "isoprenoid pathway" EXACT [] +xref: MetaCyc:PWY-922 +is_a: GO:0045337 ! farnesyl diphosphate biosynthetic process +is_a: GO:1902767 ! isoprenoid biosynthetic process via mevalonate +relationship: part_of GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0010143 +name: cutin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants." [ISBN:0028623819] +synonym: "cutin anabolism" EXACT [] +synonym: "cutin biosynthesis" EXACT [] +synonym: "cutin formation" EXACT [] +synonym: "cutin synthesis" EXACT [] +xref: MetaCyc:PWY-321 +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0010144 +name: pyridoxal phosphate biosynthetic process from pyridoxamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine." [GOC:pz] +synonym: "pyridoxal 5'-phosphate salvage from pyridoxamine" EXACT [] +synonym: "pyridoxal phosphate anabolism from pyridoxamine" EXACT [] +synonym: "pyridoxal phosphate formation from pyridoxamine" EXACT [] +synonym: "pyridoxal phosphate synthesis from pyridoxamine" EXACT [] +synonym: "vitamin B6 biosynthesis from pyridoxamine" EXACT [] +synonym: "vitamin B6 biosynthetic process from pyridoxamine" EXACT [] +is_a: GO:0009443 ! pyridoxal 5'-phosphate salvage +is_a: GO:0042818 ! pyridoxamine metabolic process + +[Term] +id: GO:0010145 +name: fructan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues." [GOC:sm] +synonym: "fructan metabolism" EXACT [] +synonym: "levan metabolic process" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0010146 +name: fructan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues." [GOC:pz] +synonym: "fructan anabolism" EXACT [] +synonym: "fructan biosynthesis" EXACT [] +synonym: "fructan formation" EXACT [] +synonym: "fructan synthesis" EXACT [] +synonym: "levan biosynthesis" EXACT [] +synonym: "levan biosynthetic process" EXACT [] +xref: MetaCyc:PWY-822 +is_a: GO:0010145 ! fructan metabolic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process + +[Term] +id: GO:0010147 +name: fructan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues." [GOC:pz] +synonym: "fructan breakdown" EXACT [] +synonym: "fructan catabolism" EXACT [] +synonym: "fructan degradation" EXACT [] +synonym: "levan catabolic process" EXACT [] +synonym: "levan catabolism" EXACT [] +xref: MetaCyc:PWY-862 +is_a: GO:0010145 ! fructan metabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process + +[Term] +id: GO:0010148 +name: transpiration +namespace: biological_process +def: "Release of water by the plant into the air as water vapor mainly through leaves." [GOC:sm, ISBN:0879015322] +xref: Wikipedia:Transpiration +is_a: GO:0006833 ! water transport + +[Term] +id: GO:0010149 +name: obsolete senescence +namespace: biological_process +def: "OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed." [GOC:mtg_sensu, ISBN:0387987819] +comment: This term was made obsolete because its name is ambiguous and it is covered by the two more specific terms: 'organ senescence ; GO:0010260' and 'cell aging ; GO:0007569'. +synonym: "senescence" EXACT [] +xref: Wikipedia:Senescence +is_obsolete: true + +[Term] +id: GO:0010150 +name: leaf senescence +namespace: biological_process +def: "The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism." [ISBN:0387987819] +is_a: GO:0090693 ! plant organ senescence +relationship: part_of GO:0048366 ! leaf development + +[Term] +id: GO:0010151 +name: chloroplast elongation +namespace: biological_process +def: "Expansion of the chloroplast that usually precedes division." [GOC:lr] +is_a: GO:0009658 ! chloroplast organization + +[Term] +id: GO:0010152 +name: pollen maturation +namespace: biological_process +def: "The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains." [PMID:11595796] +is_a: GO:0021700 ! developmental maturation +relationship: part_of GO:0009555 ! pollen development + +[Term] +id: GO:0010153 +name: obsolete polar cell elongation +namespace: biological_process +def: "OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion." [PMID:11978864] +comment: This term was made obsolete because it did not represent a process discrete from its sibling terms. +synonym: "polar cell elongation" EXACT [] +synonym: "polarity-dependent cell elongation" NARROW [] +is_obsolete: true +consider: GO:0042814 +consider: GO:0042815 + +[Term] +id: GO:0010154 +name: fruit development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant." [GOC:sm] +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0010155 +name: regulation of proton transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:sm] +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902600 ! proton transmembrane transport +relationship: regulates GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0010156 +name: obsolete sporocyte morphogenesis +namespace: biological_process +def: "OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores." [PMID:10465788] +comment: This term was made obsolete because it was incorrectly defined. +synonym: "sporocyte morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0048533 + +[Term] +id: GO:0010157 +name: response to chlorate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus." [GOC:sm] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010158 +name: abaxial cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:mg] +is_a: GO:0001708 ! cell fate specification + +[Term] +id: GO:0010159 +name: specification of animal organ position +namespace: biological_process +def: "The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ." [GOC:curators] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0009887 ! animal organ morphogenesis + +[Term] +id: GO:0010160 +name: formation of animal organ boundary +namespace: biological_process +alt_id: GO:0048862 +def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175] +synonym: "organ boundary specification" EXACT [] +is_a: GO:0003002 ! regionalization +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0048645 ! animal organ formation + +[Term] +id: GO:0010161 +name: red light signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mtg_far_red, GOC:sm] +synonym: "red light phototransduction" EXACT [GOC:signaling] +synonym: "red light signal transduction" EXACT [GOC:signaling] +synonym: "red light signalling pathway" EXACT [] +is_a: GO:0010017 ! red or far-red light signaling pathway +is_a: GO:0071491 ! cellular response to red light + +[Term] +id: GO:0010162 +name: seed dormancy process +namespace: biological_process +def: "A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors." [GOC:lr, GOC:PO_curators, ISBN:9781405139830, PO_REF:00009] +synonym: "seed dormancy" RELATED [] +xref: Wikipedia:Seed#Seed_dormancy_and_protection +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022611 ! dormancy process +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0010431 ! seed maturation + +[Term] +id: GO:0010164 +name: response to cesium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus." [GOC:sm] +synonym: "response to cesium" EXACT [GOC:mah] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010165 +name: response to X-ray +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)." [GOC:sm, Wikipedia:X-ray] +synonym: "response to X-ray radiation stimulus" EXACT [] +is_a: GO:0010212 ! response to ionizing radiation + +[Term] +id: GO:0010166 +name: wax metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids." [GOC:sm] +synonym: "wax metabolism" EXACT [] +is_a: GO:1901568 ! fatty acid derivative metabolic process +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0010167 +name: response to nitrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus." [GOC:sm] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010168 +name: ER body +namespace: cellular_component +def: "A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species." [PMID:11577182] +synonym: "endoplasmic reticulum body" EXACT [] +is_a: GO:0043231 ! intracellular membrane-bounded organelle + +[Term] +id: GO:0010169 +name: thioglucosidase complex +namespace: cellular_component +def: "A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds." [PMID:10682349] +synonym: "myrosinase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0010170 +name: glucose-1-phosphate adenylyltransferase complex +namespace: cellular_component +def: "Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits." [GOC:tb, PMID:12748181] +is_a: GO:1902503 ! adenylyltransferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0010171 +name: body morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888] +is_a: GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0010172 +name: embryonic body morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the embryonic soma are generated and organized." [GOC:ems] +is_a: GO:0010171 ! body morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0010174 +name: nucleoside transmembrane transporter activity, against a concentration gradient +namespace: molecular_function +def: "Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient." [GOC:tb] +synonym: "concentrative nucleoside transporter activity" EXACT [] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0010176 +name: homogentisate phytyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol." [MetaCyc:RXN-2541, PMID:14512521] +xref: KEGG_REACTION:R07500 +xref: MetaCyc:RXN-2541 +is_a: GO:0010354 ! homogentisate prenyltransferase activity + +[Term] +id: GO:0010177 +name: 2-(2'-methylthio)ethylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+." [MetaCyc:RXN-2202] +synonym: "methylthioalkylmalate synthase activity" BROAD [MetaCyc:RXN-2202] +xref: EC:2.3.3.17 +xref: MetaCyc:RXN-2202 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0010178 +name: IAA-amino acid conjugate hydrolase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid." [GOC:tb] +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0010179 +name: IAA-Ala conjugate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine." [MetaCyc:RXN-2981] +xref: MetaCyc:RXN-2981 +is_a: GO:0010178 ! IAA-amino acid conjugate hydrolase activity + +[Term] +id: GO:0010180 +name: thioglucosidase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme thioglucosidase." [GOC:tb] +synonym: "myrosinase binding" EXACT [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0010181 +name: FMN binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:tb] +synonym: "flavin mononucleotide binding" EXACT [] +is_a: GO:0032553 ! ribonucleotide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0050662 ! coenzyme binding + +[Term] +id: GO:0010182 +name: sugar mediated signaling pathway +namespace: biological_process +def: "The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes." [PMID:9014361] +synonym: "sugar mediated signalling" EXACT [] +is_a: GO:0009756 ! carbohydrate mediated signaling + +[Term] +id: GO:0010183 +name: pollen tube guidance +namespace: biological_process +def: "The process in which the growth of pollen tube is directed towards the female gametophyte." [GOC:lr] +is_a: GO:0022414 ! reproductive process +is_a: GO:0050918 ! positive chemotaxis +relationship: part_of GO:0048868 ! pollen tube development + +[Term] +id: GO:0010184 +name: cytokinin transport +namespace: biological_process +def: "The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:lr] +is_a: GO:0009914 ! hormone transport + +[Term] +id: GO:0010185 +name: regulation of cellular defense response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular defense response." [GOC:sm] +synonym: "regulation of cellular defence response" EXACT [] +is_a: GO:0031347 ! regulation of defense response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006968 ! cellular defense response +relationship: regulates GO:0006968 ! cellular defense response + +[Term] +id: GO:0010186 +name: positive regulation of cellular defense response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular defense response." [GOC:sm] +synonym: "activation of cellular defense response" NARROW [] +synonym: "positive regulation of cellular defence response" EXACT [] +synonym: "stimulation of cellular defense response" NARROW [] +synonym: "up regulation of cellular defense response" EXACT [] +synonym: "up-regulation of cellular defense response" EXACT [] +synonym: "upregulation of cellular defense response" EXACT [] +is_a: GO:0010185 ! regulation of cellular defense response +is_a: GO:0031349 ! positive regulation of defense response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006968 ! cellular defense response +relationship: positively_regulates GO:0006968 ! cellular defense response + +[Term] +id: GO:0010187 +name: negative regulation of seed germination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination." [GOC:tb] +synonym: "down regulation of seed germination" EXACT [] +synonym: "down-regulation of seed germination" EXACT [] +synonym: "downregulation of seed germination" EXACT [] +synonym: "inhibition of seed germination" NARROW [] +is_a: GO:0010029 ! regulation of seed germination +is_a: GO:0048581 ! negative regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009845 ! seed germination +relationship: negatively_regulates GO:0009845 ! seed germination + +[Term] +id: GO:0010188 +name: response to microbial phytotoxin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants." [GOC:sm] +is_a: GO:0009636 ! response to toxic substance + +[Term] +id: GO:0010189 +name: vitamin E biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant." [GOC:mg] +synonym: "alpha-tocopherol biosynthesis" NARROW [] +synonym: "alpha-tocopherol biosynthetic process" NARROW [] +synonym: "tocopherol biosynthesis" EXACT [] +synonym: "tocopherol biosynthetic process" EXACT [] +synonym: "vitamin E anabolism" EXACT [] +synonym: "vitamin E biosynthesis" EXACT [] +synonym: "vitamin E formation" EXACT [] +synonym: "vitamin E synthesis" EXACT [] +xref: MetaCyc:PWY-1422 +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042360 ! vitamin E metabolic process +is_a: GO:0042362 ! fat-soluble vitamin biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0010190 +name: cytochrome b6f complex assembly +namespace: biological_process +def: "Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents." [GOC:tb] +synonym: "cytochrome b6f complex biogenesis" EXACT [] +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0010191 +name: mucilage metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants." [GOC:sm] +subset: goslim_pir +synonym: "mucilage metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0010192 +name: mucilage biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants." [GOC:sm] +synonym: "mucilage anabolism" EXACT [] +synonym: "mucilage biosynthesis" EXACT [] +synonym: "mucilage formation" EXACT [] +synonym: "mucilage synthesis" EXACT [] +is_a: GO:0010191 ! mucilage metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0010193 +name: response to ozone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus." [GOC:sm] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic + +[Term] +id: GO:0010194 +name: obsolete microRNA metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity." [GOC:sm] +comment: This term was made obsolete because it implies further processing of an end product rather than its production. +synonym: "microRNA metabolic process" EXACT [] +is_obsolete: true +replaced_by: GO:0035196 + +[Term] +id: GO:0010195 +name: obsolete microRNA biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity." [GOC:sm] +comment: This term was made obsolete because it represents a process that is not known to occur. +synonym: "microRNA anabolism" EXACT [] +synonym: "microRNA biosynthesis" EXACT [] +synonym: "microRNA biosynthetic process" EXACT [] +synonym: "microRNA formation" EXACT [] +synonym: "microRNA synthesis" EXACT [] +synonym: "miRNA biosynthesis" EXACT [] +synonym: "miRNA biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0035196 + +[Term] +id: GO:0010196 +name: nonphotochemical quenching +namespace: biological_process +def: "The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage." [PMID:10667783, PMID:10938857] +is_a: GO:1990066 ! energy quenching + +[Term] +id: GO:0010197 +name: polar nucleus fusion +namespace: biological_process +def: "The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized." [GOC:mtg_plant, GOC:sm] +is_a: GO:0000741 ! karyogamy +relationship: part_of GO:0009559 ! embryo sac central cell differentiation + +[Term] +id: GO:0010198 +name: synergid death +namespace: biological_process +alt_id: GO:0048470 +def: "Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles." [GOC:isa_complete, GOC:sm, PMID:12215516] +synonym: "synergid cell death" EXACT [] +synonym: "synergid degeneration" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010623 ! programmed cell death involved in cell development +relationship: part_of GO:0009856 ! pollination + +[Term] +id: GO:0010199 +name: organ boundary specification between lateral organs and the meristem +namespace: biological_process +def: "The process in which boundaries between lateral organs and the meristem is established and maintained." [PMID:12068116] +is_a: GO:0090691 ! formation of plant organ boundary + +[Term] +id: GO:0010200 +name: response to chitin +namespace: biological_process +def: "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:sm] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010201 +name: response to continuous far red light stimulus by the high-irradiance response system +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence." [GOC:mtg_far_red, GOC:sm] +is_a: GO:0010218 ! response to far red light + +[Term] +id: GO:0010202 +name: response to low fluence red light stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec." [GOC:mtg_far_red, GOC:sm] +is_a: GO:0009645 ! response to low light intensity stimulus +is_a: GO:0010114 ! response to red light + +[Term] +id: GO:0010203 +name: response to very low fluence red light stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec." [GOC:mtg_far_red, GOC:sm] +is_a: GO:0010114 ! response to red light +is_a: GO:0055122 ! response to very low light intensity stimulus + +[Term] +id: GO:0010205 +name: photoinhibition +namespace: biological_process +def: "The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II." [GOC:mtg_electron_transport, PMID:12068126] +synonym: "photosystem II inhibition" BROAD [] +xref: Wikipedia:Photoinhibition +is_a: GO:0009644 ! response to high light intensity +is_a: GO:0043155 ! negative regulation of photosynthesis, light reaction +relationship: negatively_regulates GO:0009767 ! photosynthetic electron transport chain +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0010206 +name: photosystem II repair +namespace: biological_process +def: "Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition." [GOC:sm] +is_a: GO:0030091 ! protein repair +relationship: part_of GO:0009765 ! photosynthesis, light harvesting +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0010207 +name: photosystem II assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms." [GOC:aa, GOC:pz] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0010208 +name: pollen wall assembly +namespace: biological_process +def: "The formation of reticulate pollen wall pattern consisting of two layers, exine and intine." [PMID:11743117] +synonym: "pollen wall formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0045229 ! external encapsulating structure organization +relationship: part_of GO:0009555 ! pollen development + +[Term] +id: GO:0010209 +name: vacuolar sorting signal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole." [GOC:mah] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0010210 +name: IAA-Phe conjugate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine." [GOC:syr] +is_a: GO:0010178 ! IAA-amino acid conjugate hydrolase activity + +[Term] +id: GO:0010211 +name: IAA-Leu conjugate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine." [MetaCyc:RXN-2982] +xref: MetaCyc:RXN-2982 +is_a: GO:0010178 ! IAA-amino acid conjugate hydrolase activity + +[Term] +id: GO:0010212 +name: response to ionizing radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." [PMID:12509526] +synonym: "response to ionising radiation" EXACT [] +synonym: "response to ionizing radiation stimulus" EXACT [] +is_a: GO:0009314 ! response to radiation + +[Term] +id: GO:0010213 +name: non-photoreactive DNA repair +namespace: biological_process +def: "A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated." [GOC:syr] +synonym: "light-independent DNA repair" EXACT [GOC:syr] +is_a: GO:0006281 ! DNA repair + +[Term] +id: GO:0010214 +name: seed coat development +namespace: biological_process +def: "The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0010215 +name: cellulose microfibril organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall." [GOC:mah, PMID:12468730] +synonym: "cellulose microfibril organisation" EXACT [] +is_a: GO:0030198 ! extracellular matrix organization +relationship: part_of GO:0071668 ! plant-type cell wall assembly + +[Term] +id: GO:0010216 +name: maintenance of DNA methylation +namespace: biological_process +def: "Any process involved in maintaining the methylation state of a nucleotide sequence." [PMID:11898023] +is_a: GO:0006259 ! DNA metabolic process +relationship: has_part GO:0006306 ! DNA methylation + +[Term] +id: GO:0010217 +name: cellular aluminum ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell." [GOC:lr, GOC:mah] +synonym: "cellular aluminium ion homeostasis" EXACT [GOC:mah] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0055079 ! aluminum ion homeostasis + +[Term] +id: GO:0010218 +name: response to far red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mtg_far_red, GOC:tb] +synonym: "response to far red light stimulus" EXACT [] +is_a: GO:0009639 ! response to red or far red light + +[Term] +id: GO:0010219 +name: regulation of vernalization response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures." [GOC:sm] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010048 ! vernalization response +relationship: regulates GO:0010048 ! vernalization response + +[Term] +id: GO:0010220 +name: positive regulation of vernalization response +namespace: biological_process +def: "Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures." [GOC:sm] +synonym: "activation of vernalization response" NARROW [] +synonym: "stimulation of vernalization response" NARROW [] +synonym: "up regulation of vernalization response" EXACT [] +synonym: "up-regulation of vernalization response" EXACT [] +synonym: "upregulation of vernalization response" EXACT [] +is_a: GO:0010219 ! regulation of vernalization response +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010048 ! vernalization response +relationship: positively_regulates GO:0010048 ! vernalization response + +[Term] +id: GO:0010221 +name: negative regulation of vernalization response +namespace: biological_process +def: "Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures." [GOC:sm] +synonym: "down regulation of vernalization response" EXACT [] +synonym: "down-regulation of vernalization response" EXACT [] +synonym: "downregulation of vernalization response" EXACT [] +synonym: "inhibition of vernalization response" NARROW [] +is_a: GO:0010219 ! regulation of vernalization response +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010048 ! vernalization response +relationship: negatively_regulates GO:0010048 ! vernalization response + +[Term] +id: GO:0010222 +name: stem vascular tissue pattern formation +namespace: biological_process +def: "Vascular tissue pattern formation as it occurs in the stem of vascular plants." [GOC:tb] +is_a: GO:0010051 ! xylem and phloem pattern formation + +[Term] +id: GO:0010223 +name: secondary shoot formation +namespace: biological_process +def: "The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs." [GOC:tb, PMID:12815068] +synonym: "auxiliary shoot formation" RELATED [] +synonym: "axillary shoot formation" RELATED [] +synonym: "axillary shoot system formation" EXACT [] +synonym: "shoot branching" RELATED [] +is_a: GO:0001763 ! morphogenesis of a branching structure +is_a: GO:0010346 ! shoot axis formation + +[Term] +id: GO:0010224 +name: response to UV-B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm." [GOC:tb] +synonym: "response to medium wave ultraviolet light stimulus" EXACT [] +synonym: "response to medium wave ultraviolet radiation stimulus" EXACT [] +synonym: "response to UV-B light stimulus" EXACT [] +synonym: "response to UV-B radiation stimulus" EXACT [] +synonym: "response to UVB light stimulus" EXACT [] +synonym: "response to UVB radiation stimulus" EXACT [] +is_a: GO:0009411 ! response to UV + +[Term] +id: GO:0010225 +name: response to UV-C +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm." [GOC:tb] +synonym: "response to germicidal ultraviolet light stimulus" EXACT [] +synonym: "response to germicidal ultraviolet radiation stimulus" EXACT [] +synonym: "response to shortwave ultraviolet light stimulus" EXACT [] +synonym: "response to shortwave ultraviolet radiation stimulus" EXACT [] +synonym: "response to UV-C light stimulus" EXACT [] +synonym: "response to UV-C radiation stimulus" EXACT [] +synonym: "response to UVC light stimulus" EXACT [] +synonym: "response to UVC radiation stimulus" EXACT [] +is_a: GO:0009411 ! response to UV + +[Term] +id: GO:0010226 +name: response to lithium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus." [GOC:tb] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010227 +name: floral organ abscission +namespace: biological_process +def: "The controlled shedding of floral organs." [GOC:PO_curators, PMID:12972671, PO:0025395] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009838 ! abscission +relationship: part_of GO:0048437 ! floral organ development + +[Term] +id: GO:0010228 +name: vegetative to reproductive phase transition of meristem +namespace: biological_process +def: "The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence." [GOC:tb] +synonym: "floral evocation" RELATED [DOI:10.1146/annurev.pp.39.060188.001135] +synonym: "flowering" RELATED [] +synonym: "transition from vegetative to reproductive phase" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0009791 ! post-embryonic development +relationship: part_of GO:0048608 ! reproductive structure development + +[Term] +id: GO:0010229 +name: inflorescence development +namespace: biological_process +def: "The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure." [GOC:tb] +is_a: GO:0090567 ! reproductive shoot system development + +[Term] +id: GO:0010230 +name: alternative respiration +namespace: biological_process +def: "Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa." [ISBN:0943088399] +is_a: GO:0009060 ! aerobic respiration + +[Term] +id: GO:0010231 +name: maintenance of seed dormancy +namespace: biological_process +def: "Any process that maintains a seed in a dormant state." [ISBN:9781405139830, PMID:9580097] +is_a: GO:0010162 ! seed dormancy process +is_a: GO:0097437 ! maintenance of dormancy + +[Term] +id: GO:0010232 +name: vascular transport +namespace: biological_process +def: "The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane." [GOC:sm] +is_a: GO:0003018 ! vascular process in circulatory system +is_a: GO:0006810 ! transport + +[Term] +id: GO:0010233 +name: phloem transport +namespace: biological_process +def: "The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues." [GOC:sm, PMID:19025382] +is_a: GO:0010232 ! vascular transport + +[Term] +id: GO:0010234 +name: anther wall tapetum cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:mg] +synonym: "tapetal cell fate specification" BROAD [GOC:tb] +is_a: GO:0001708 ! cell fate specification +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0048657 ! anther wall tapetum cell differentiation + +[Term] +id: GO:0010235 +name: guard mother cell cytokinesis +namespace: biological_process +def: "The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells." [GOC:tb] +synonym: "guard mother cell division" EXACT [] +is_a: GO:0000911 ! cytokinesis by cell plate formation +relationship: part_of GO:0010440 ! stomatal lineage progression + +[Term] +id: GO:0010236 +name: plastoquinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast." [GOC:sm] +synonym: "plastoquinone anabolism" EXACT [] +synonym: "plastoquinone biosynthesis" EXACT [] +synonym: "plastoquinone formation" EXACT [] +synonym: "plastoquinone synthesis" EXACT [] +xref: MetaCyc:PWY-1581 +is_a: GO:1901663 ! quinone biosynthetic process + +[Term] +id: GO:0010238 +name: response to proline +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus." [GOC:sm] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0010239 +name: chloroplast mRNA processing +namespace: biological_process +def: "Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs." [GOC:tb, PMID:9648738] +is_a: GO:0006397 ! mRNA processing +is_a: GO:0031425 ! chloroplast RNA processing +intersection_of: GO:0006397 ! mRNA processing +intersection_of: occurs_in GO:0009507 ! chloroplast +relationship: occurs_in GO:0009507 ! chloroplast +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0010240 +name: plastid pyruvate dehydrogenase complex +namespace: cellular_component +def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria." [GOC:mtg_sensu, PMID:9393637] +synonym: "dehydrogenase complex" BROAD [] +is_a: GO:0045254 ! pyruvate dehydrogenase complex +intersection_of: GO:0045254 ! pyruvate dehydrogenase complex +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0010241 +name: ent-kaurene oxidation to kaurenoic acid +namespace: biological_process +def: "The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase." [GOC:tb] +comment: Note that this term was in molecular function but was moved to biological process as it represents three successive reactions. +synonym: "ent-kaurene oxidation to ent-kaur-16-en-19-oate" EXACT [] +synonym: "ent-kaurene oxidation to ent-kaurenoate" EXACT [] +synonym: "ent-kaurene oxidation to kaurenoic acid by ent-kaurene oxidase" EXACT [] +is_a: GO:0033331 ! ent-kaurene metabolic process +is_a: GO:0055114 ! oxidation-reduction process +relationship: has_part GO:0052615 ! ent-kaurene oxidase activity +relationship: has_part GO:0052616 ! ent-kaur-16-en-19-ol oxidase activity +relationship: has_part GO:0052617 ! ent-kaur-16-en-19-al oxidase activity + +[Term] +id: GO:0010242 +name: oxygen evolving activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle." [GOC:kd, GOC:syr, PMID:17091926, PMID:7948862] +synonym: "photosynthetic water oxidation" EXACT [] +xref: MetaCyc:PSII-RXN +xref: MetaCyc:RXN0-5265 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0010243 +name: response to organonitrogen compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419] +synonym: "response to organic nitrogen" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901698 ! response to nitrogen compound + +[Term] +id: GO:0010244 +name: response to low fluence blue light stimulus by blue low-fluence system +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes." [GOC:mtg_far_red, PMID:10398709] +synonym: "response to low fluence blue light" BROAD [] +synonym: "response to low fluence blue light by blf system" EXACT [] +is_a: GO:0009637 ! response to blue light +is_a: GO:0009645 ! response to low light intensity stimulus + +[Term] +id: GO:0010245 +name: radial microtubular system formation +namespace: biological_process +def: "Formation of radial microtubular systems during male meiotic cytokinesis in plants." [GOC:syr] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0010246 +name: rhamnogalacturonan I biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide." [GOC:pz] +synonym: "rhamnogalacturonan I anabolism" EXACT [] +synonym: "rhamnogalacturonan I biosynthesis" EXACT [] +synonym: "rhamnogalacturonan I formation" EXACT [] +synonym: "rhamnogalacturonan I synthesis" EXACT [] +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0010395 ! rhamnogalacturonan I metabolic process + +[Term] +id: GO:0010247 +name: detection of phosphate ion +namespace: biological_process +def: "The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal." [GOC:sm] +synonym: "phosphate ion detection" EXACT [] +synonym: "phosphate ion perception" RELATED [] +synonym: "phosphate ion sensing" RELATED [] +is_a: GO:0009593 ! detection of chemical stimulus + +[Term] +id: GO:0010248 +name: establishment or maintenance of transmembrane electrochemical gradient +namespace: biological_process +def: "The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore." [GOC:mah, GOC:sm] +is_a: GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0010249 +name: auxin conjugate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving auxin conjugates, a bound form of auxin." [GOC:sm] +synonym: "auxin conjugate metabolism" EXACT [] +is_a: GO:0009850 ! auxin metabolic process + +[Term] +id: GO:0010250 +name: S-methylmethionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle." [PMID:12692340] +synonym: "S-methylmethionine anabolism" EXACT [] +synonym: "S-methylmethionine biosynthesis" EXACT [] +synonym: "S-methylmethionine formation" EXACT [] +synonym: "S-methylmethionine synthesis" EXACT [] +is_a: GO:0033477 ! S-methylmethionine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0010252 +name: auxin homeostasis +namespace: biological_process +def: "A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation." [PMID:22504182] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0010253 +name: UDP-rhamnose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate." [PMID:15134748] +synonym: "UDP-rhamnose anabolism" EXACT [] +synonym: "UDP-rhamnose biosynthesis" EXACT [] +synonym: "UDP-rhamnose formation" EXACT [] +synonym: "UDP-rhamnose synthesis" EXACT [] +xref: MetaCyc:PWY-3261 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033478 ! UDP-rhamnose metabolic process + +[Term] +id: GO:0010254 +name: nectary development +namespace: biological_process +def: "The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure." [GOC:lr] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0010255 +name: glucose mediated signaling pathway +namespace: biological_process +def: "The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes." [GOC:sm] +synonym: "glucose mediated signalling" EXACT [] +is_a: GO:0009757 ! hexose mediated signaling +relationship: part_of GO:0071333 ! cellular response to glucose stimulus + +[Term] +id: GO:0010256 +name: endomembrane system organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm] +subset: goslim_drosophila +synonym: "endomembrane organization" EXACT [] +synonym: "endomembrane system organisation" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0010257 +name: NADH dehydrogenase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex." [GOC:sm] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0010258 +name: NADH dehydrogenase complex (plastoquinone) assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I." [PMID:15608332] +is_a: GO:0010257 ! NADH dehydrogenase complex assembly +is_a: GO:0010275 ! NAD(P)H dehydrogenase complex assembly + +[Term] +id: GO:0010259 +name: multicellular organism aging +namespace: biological_process +def: "An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] +is_a: GO:0007275 ! multicellular organism development +is_a: GO:0007568 ! aging + +[Term] +id: GO:0010260 +name: animal organ senescence +namespace: biological_process +alt_id: GO:0010261 +def: "The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism." [GOC:tb] +is_a: GO:0007568 ! aging +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0010262 +name: somatic embryogenesis +namespace: biological_process +def: "Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes." [GOC:sm, PMID:9611173] +is_a: GO:0009793 ! embryo development ending in seed dormancy +is_a: GO:0031099 ! regeneration + +[Term] +id: GO:0010263 +name: tricyclic triterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings." [GOC:ct] +synonym: "tricyclic triterpenoid anabolism" EXACT [GOC:tair_curators] +synonym: "tricyclic triterpenoid biosynthesis" EXACT [GOC:tair_curators] +synonym: "tricyclic triterpenoid formation" EXACT [GOC:tair_curators] +synonym: "tricyclic triterpenoid synthesis" EXACT [GOC:tair_curators] +is_a: GO:0010683 ! tricyclic triterpenoid metabolic process +is_a: GO:0016104 ! triterpenoid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0010264 +name: myo-inositol hexakisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds." [PMID:16107538] +synonym: "myo-inositol hexakisphosphate anabolism" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthesis" EXACT [] +synonym: "myo-inositol hexakisphosphate formation" EXACT [] +synonym: "myo-inositol hexakisphosphate synthesis" EXACT [] +synonym: "phytate biosynthesis" EXACT [] +synonym: "phytate biosynthetic process" EXACT [] +is_a: GO:0032958 ! inositol phosphate biosynthetic process +is_a: GO:0033517 ! myo-inositol hexakisphosphate metabolic process + +[Term] +id: GO:0010265 +name: SCF complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex." [GOC:pz] +is_a: GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0010266 +name: response to vitamin B1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus." [GOC:pz] +synonym: "response to thiamin" EXACT [] +synonym: "response to thiamine" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0010267 +name: production of ta-siRNAs involved in RNA interference +namespace: biological_process +def: "Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs." [GOC:tb, PMID:16129836] +synonym: "RNA interference, production of ta-siRNAs" EXACT [GOC:mah] +is_a: GO:0030422 ! production of siRNA involved in RNA interference + +[Term] +id: GO:0010268 +name: brassinosteroid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell." [PMID:15908602] +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0010269 +name: response to selenium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion." [GOC:mg] +is_a: GO:0010035 ! response to inorganic substance + +[Term] +id: GO:0010270 +name: photosystem II oxygen evolving complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ." [GOC:aa, PMID:16282331] +synonym: "OEC (PSII) ASSEMBLY" EXACT [PMID:16282331] +is_a: GO:0010207 ! photosystem II assembly + +[Term] +id: GO:0010271 +name: regulation of chlorophyll catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll." [PMID:16361392] +is_a: GO:0090056 ! regulation of chlorophyll metabolic process +is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015996 ! chlorophyll catabolic process +relationship: regulates GO:0015996 ! chlorophyll catabolic process + +[Term] +id: GO:0010272 +name: response to silver ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus." [PMID:16367966] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010273 +name: detoxification of copper ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion." [GOC:kmv, PMID:16367966] +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:1990169 ! stress response to copper ion + +[Term] +id: GO:0010274 +name: hydrotropism +namespace: biological_process +def: "Growth or movement in a sessile organism toward or away from water, as of the roots of a plant." [ISBN:0395825172] +xref: Wikipedia:Hydrotropism +is_a: GO:0009606 ! tropism + +[Term] +id: GO:0010275 +name: NAD(P)H dehydrogenase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool." [GOC:sm] +synonym: "NAD(P)H dehydrogenase complex (plastoquinone) assembly" NARROW [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0010276 +name: phytol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+." [MetaCyc:RXN-7683] +xref: EC:2.7.1 +xref: MetaCyc:RXN-7683 +is_a: GO:0016301 ! kinase activity + +[Term] +id: GO:0010277 +name: chlorophyllide a oxygenase [overall] activity +namespace: molecular_function +alt_id: GO:0046407 +def: "Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+." [EC:1.13.12.14, MetaCyc:RXN-7677] +comment: This is a process composed of two reactions represented by the terms 'GO:0052606 : chlorophyllide a oxygenase activity' and 'GO:0052607 : 7-hydroxy-chlorophyllide a oxygenase activity'. +synonym: "CAO activity" BROAD [EC:1.13.12.14] +synonym: "chlorophyll a oxygenation activity" EXACT [] +synonym: "chlorophyll b synthesis activity" EXACT [] +synonym: "chlorophyll-b synthesis activity" EXACT [EC:1.13.12.14] +synonym: "chlorophyllide a:oxygen 7-oxidoreduction activity" EXACT [EC:1.13.12.14] +synonym: "chlorophyllide-a oxygenation activity" EXACT [EC:1.13.12.14] +xref: EC:1.14.13.122 +xref: RHEA:30359 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0010278 +name: chloroplast outer membrane translocon +namespace: cellular_component +def: "The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner." [PMID:11299338] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009707 ! chloroplast outer membrane + +[Term] +id: GO:0010279 +name: indole-3-acetic acid amido synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate." [PMID:15659623] +synonym: "IAA amido synthetase activity" EXACT [] +synonym: "IAA amino acid conjugate synthetase activity" EXACT [GOC:kad] +synonym: "IAA amino acid synthetase activity" EXACT [GOC:kad] +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0010280 +name: UDP-L-rhamnose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O." [MetaCyc:RXN-5482, PMID:14701918] +synonym: "UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity" NARROW [GOC:tb] +xref: MetaCyc:RXN-5482 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0010282 +name: senescence-associated vacuole +namespace: cellular_component +def: "A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast." [PMID:15743448] +synonym: "senescence associated vacuole" EXACT [] +is_a: GO:0000323 ! lytic vacuole +is_a: GO:0000325 ! plant-type vacuole + +[Term] +id: GO:0010283 +name: pinoresinol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+." [PMID:10066819, PMID:7592828] +xref: MetaCyc:RXN-8678 +xref: MetaCyc:RXN-8683 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0010284 +name: lariciresinol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+." [PMID:10066819, PMID:7592828] +xref: MetaCyc:RXN-8679 +xref: MetaCyc:RXN-8684 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0010285 +name: L,L-diaminopimelate aminotransferase activity +namespace: molecular_function +alt_id: GO:0043742 +def: "Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+)." [EC:2.6.1.83, RHEA:23988] +synonym: "LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity" EXACT [] +synonym: "LL-DAP aminotransferase activity" EXACT [EC:2.6.1.83] +synonym: "LL-DAP-AT activity" EXACT [EC:2.6.1.83] +synonym: "LL-diaminopimelate aminotransferase activity" EXACT [] +synonym: "LL-diaminopimelate transaminase activity" EXACT [EC:2.6.1.83] +xref: EC:2.6.1.83 +xref: KEGG_REACTION:R07613 +xref: MetaCyc:RXN-7737 +xref: RHEA:23988 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0010286 +name: heat acclimation +namespace: biological_process +def: "Any process that increases heat tolerance of an organism in response to high temperatures." [GOC:tair_curators] +synonym: "thermotolerance" RELATED [GOC:tb] +is_a: GO:0009408 ! response to heat + +[Term] +id: GO:0010287 +name: plastoglobule +namespace: cellular_component +alt_id: GO:0010502 +def: "A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids." [GOC:tair_curators, PMID:16461379] +synonym: "PG" EXACT [] +synonym: "plastoglobuli" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0010288 +name: response to lead ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus." [GOC:tair_curators, PMID:16461380] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0010289 +name: homogalacturonan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3." [PMID:12913136, PMID:16540543] +xref: MetaCyc:PWY-1061 +is_a: GO:0010394 ! homogalacturonan metabolic process +is_a: GO:0052325 ! cell wall pectin biosynthetic process + +[Term] +id: GO:0010290 +name: chlorophyll catabolite transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other." [PMID:9681016] +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0010291 +name: carotene beta-ring hydroxylase activity +namespace: molecular_function +alt_id: GO:0042411 +def: "Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene." [MetaCyc:MONOMER-12386, PMID:16492736] +synonym: "beta-carotene hydroxylase activity" NARROW [] +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0010292 +name: GTP:GDP antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out)." [PMID:10514379, PMID:12553910, PMID:16553903] +is_a: GO:0001409 ! guanine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015211 ! purine nucleoside transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0010293 +name: abscisic aldehyde oxidase activity +namespace: molecular_function +alt_id: GO:0033725 +def: "Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+)." [EC:1.2.3.14, RHEA:20529] +synonym: "AAO3" RELATED [EC:1.2.3.14] +synonym: "abscisic-aldehyde oxidase activity" EXACT [EC:1.2.3.14] +synonym: "abscisic-aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.14] +synonym: "AOdelta" RELATED [EC:1.2.3.14] +xref: EC:1.2.3.14 +xref: KEGG_REACTION:R06957 +xref: MetaCyc:1.2.3.14-RXN +xref: RHEA:20529 +is_a: GO:0018488 ! aryl-aldehyde oxidase activity + +[Term] +id: GO:0010294 +name: abscisic acid glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP." [DOI:10.1016/j.tetasy.2004.11.062] +xref: MetaCyc:RXN-8155 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0010295 +name: (+)-abscisic acid 8'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+)." [EC:1.14.14.137, RHEA:12897] +synonym: "(+)-ABA 8'-hydroxylase activity" EXACT [EC:1.14.14.137] +synonym: "ABA 8'-hydroxylase activity" EXACT [EC:1.14.14.137] +synonym: "ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity" RELATED [] +synonym: "abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)" EXACT [EC:1.14.14.137] +synonym: "abscisic acid 8'-hydroxylase activity" EXACT [] +xref: EC:1.14.14.137 +xref: KEGG_REACTION:R07202 +xref: MetaCyc:1.14.13.93-RXN +xref: RHEA:12897 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0010296 +name: prenylcysteine methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+." [MetaCyc:RXN-8409, PMID:16870359] +xref: EC:3.1.1 +xref: MetaCyc:RXN-8409 +is_a: GO:0051723 ! protein methylesterase activity + +[Term] +id: GO:0010297 +name: heteropolysaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with heteropolysaccharides. A heteropolysaccharide is a glycan composed of more than one type of monosaccharide residue." [PMID:16640603] +synonym: "heteroglycan binding" EXACT [] +is_a: GO:0030247 ! polysaccharide binding + +[Term] +id: GO:0010298 +name: dihydrocamalexic acid decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+." [MetaCyc:RXN-8275, PMID:16766671] +xref: MetaCyc:RXN-8275 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0010299 +name: detoxification of cobalt ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion." [GOC:tair_curators] +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:0032025 ! response to cobalt ion + +[Term] +id: GO:0010301 +name: xanthoxin dehydrogenase activity +namespace: molecular_function +alt_id: GO:0033710 +def: "Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH." [EC:1.1.1.288, RHEA:12548] +synonym: "ABA2" RELATED [EC:1.1.1.288] +synonym: "xanthoxin oxidase activity" EXACT [EC:1.1.1.288] +synonym: "xanthoxin:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.288] +xref: EC:1.1.1.288 +xref: KEGG_REACTION:R06954 +xref: MetaCyc:1.1.1.288-RXN +xref: RHEA:12548 +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity + +[Term] +id: GO:0010303 +name: limit dextrinase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan." [EC:3.2.1.142] +synonym: "amylopectin-1,6-glucosidase activity" EXACT [EC:3.2.1.142] +synonym: "dextrin alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.142] +synonym: "R-enzyme" RELATED [EC:3.2.1.142] +xref: EC:3.2.1.142 +xref: MetaCyc:3.2.1.10-RXN +xref: MetaCyc:3.2.1.142-RXN +xref: MetaCyc:RXN-1824 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0010304 +name: PSII associated light-harvesting complex II catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II." [GOC:mah, PMID:16157880] +synonym: "LHCII catabolism" RELATED [] +is_a: GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0010305 +name: leaf vascular tissue pattern formation +namespace: biological_process +def: "Vascular tissue pattern formation as it occurs in the leaf of vascular plants." [GOC:tair_curators] +is_a: GO:0010051 ! xylem and phloem pattern formation + +[Term] +id: GO:0010306 +name: rhamnogalacturonan II biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms." [PMID:12754267] +is_a: GO:0010396 ! rhamnogalacturonan II metabolic process +is_a: GO:0052325 ! cell wall pectin biosynthetic process + +[Term] +id: GO:0010307 +name: acetylglutamate kinase regulator activity +namespace: molecular_function +def: "Modulates the enzyme activity of acetylglutamate kinase." [PMID:16377628] +is_a: GO:0019207 ! kinase regulator activity +relationship: regulates GO:0003991 ! acetylglutamate kinase activity + +[Term] +id: GO:0010308 +name: acireductone dioxygenase (Ni2+-requiring) activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate." [EC:1.13.11.53, RHEA:14161] +synonym: "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)" EXACT [EC:1.13.11.53] +synonym: "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity" BROAD [EC:1.13.11.53] +synonym: "acireductone dioxygenase activity" BROAD [EC:1.13.11.53] +synonym: "ARD activity" RELATED [EC:1.13.11.53] +synonym: "E-2 activity" RELATED [EC:1.13.11.53] +xref: EC:1.13.11.53 +xref: KEGG_REACTION:R07363 +xref: MetaCyc:R146-RXN +xref: RHEA:14161 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0010309 +name: acireductone dioxygenase [iron(II)-requiring] activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+)." [EC:1.13.11.54, RHEA:24504] +synonym: "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity" EXACT [] +synonym: "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)" EXACT [EC:1.13.11.54] +synonym: "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase" BROAD [] +synonym: "aci-reductone dioxygenase" BROAD [] +synonym: "acireductone dioxygenase (Fe2+-requiring) activity" EXACT [] +synonym: "acireductone dioxygenase activity" BROAD [EC:1.13.11.54] +synonym: "ARD'" RELATED [] +synonym: "ARD1" RELATED [] +synonym: "E-2'" RELATED [] +xref: EC:1.13.11.54 +xref: KEGG_REACTION:R07364 +xref: MetaCyc:R147-RXN +xref: Reactome:R-HSA-1237119 "Acireductone is oxidized to MOB" +xref: RHEA:24504 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0010310 +name: regulation of hydrogen peroxide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide." [PMID:14765119] +synonym: "regulation of hydrogen peroxide metabolism" EXACT [] +is_a: GO:0051193 ! regulation of cofactor metabolic process +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042743 ! hydrogen peroxide metabolic process +relationship: regulates GO:0042743 ! hydrogen peroxide metabolic process + +[Term] +id: GO:0010311 +name: lateral root formation +namespace: biological_process +alt_id: GO:0010386 +def: "The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper." [GOC:tair_curators, PMID:17259263] +synonym: "lateral root primordium development" EXACT [] +is_a: GO:0009791 ! post-embryonic development +is_a: GO:1905393 ! plant organ formation +relationship: part_of GO:0010102 ! lateral root morphogenesis + +[Term] +id: GO:0010312 +name: detoxification of zinc ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion." [GOC:tair_curators] +is_a: GO:0098754 ! detoxification +relationship: part_of GO:1990359 ! stress response to zinc ion + +[Term] +id: GO:0010313 +name: phytochrome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phytochrome." [PMID:15486102] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0010314 +name: phosphatidylinositol-5-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position." [GOC:bf, GOC:tair_curators] +is_a: GO:1901981 ! phosphatidylinositol phosphate binding + +[Term] +id: GO:0010315 +name: auxin efflux +namespace: biological_process +def: "The process involved in the transport of auxin out of the cell." [GOC:tair_curators, PMID:16990790] +synonym: "auxin export" EXACT [] +is_a: GO:0010928 ! regulation of auxin mediated signaling pathway +is_a: GO:0060918 ! auxin transport + +[Term] +id: GO:0010316 +name: pyrophosphate-dependent phosphofructokinase complex +namespace: cellular_component +def: "Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate." [PMID:2170409] +subset: goslim_pir +synonym: "PFK complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0010317 +name: pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex +namespace: cellular_component +def: "Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity." [PMID:2170409] +synonym: "PFK complex, alpha-subunit" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0010316 ! pyrophosphate-dependent phosphofructokinase complex + +[Term] +id: GO:0010318 +name: pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex +namespace: cellular_component +def: "Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity." [PMID:2170409] +synonym: "PFK complex, beta-subunit" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0010316 ! pyrophosphate-dependent phosphofructokinase complex + +[Term] +id: GO:0010319 +name: stromule +namespace: cellular_component +def: "Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types." [PMID:15272881, PMID:15699062, PMID:16582010] +synonym: "Stroma-filled tubule" RELATED [] +xref: Wikipedia:Stromule +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009526 ! plastid envelope + +[Term] +id: GO:0010320 +name: obsolete arginine/lysine endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles." [GOC:tair_curators] +comment: This term was made obsolete because it was defined incorrectly: there are no known peptidases using a catalytic mechanism involving arginine and lysine, and the Arabidopsis metacaspases that prompted addition of this term are in fact cysteine-type endopeptidases. +synonym: "arginine/lysine endopeptidase activity" EXACT [] +is_obsolete: true +consider: GO:0004175 +consider: GO:0004197 + +[Term] +id: GO:0010321 +name: regulation of vegetative phase change +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development." [GOC:tair_curators] +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010050 ! vegetative phase change +relationship: regulates GO:0010050 ! vegetative phase change + +[Term] +id: GO:0010322 +name: regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)." [PMID:16531478] +synonym: "regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +relationship: regulates GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway + +[Term] +id: GO:0010323 +name: negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)." [PMID:16531478] +synonym: "down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +synonym: "down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +synonym: "downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +synonym: "inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" NARROW [] +synonym: "negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +is_a: GO:0010322 ! regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +relationship: negatively_regulates GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway + +[Term] +id: GO:0010324 +name: membrane invagination +namespace: biological_process +alt_id: GO:1902534 +def: "The infolding of a membrane." [GOC:tb] +subset: goslim_yeast +synonym: "single-organism membrane invagination" RELATED [] +is_a: GO:0061024 ! membrane organization +created_by: jl +creation_date: 2013-12-02T13:58:34Z + +[Term] +id: GO:0010325 +name: raffinose family oligosaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization)." [GOC:tair_curators] +synonym: "raffinose family oligosaccharide biosynthesis" EXACT [] +is_a: GO:0009312 ! oligosaccharide biosynthetic process + +[Term] +id: GO:0010326 +name: methionine-oxo-acid transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid." [MetaCyc:RXN-2201, PMID:17056707] +xref: MetaCyc:RXN-2201 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0010327 +name: acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate." [PMID:17163883] +synonym: "hexenol acetyltransferase" RELATED [] +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0010328 +name: auxin influx transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of auxin, from one side of a membrane to the other, into a cell." [PMID:16839804] +synonym: "auxin influx facilitator" RELATED [] +is_a: GO:0080161 ! auxin transmembrane transporter activity +relationship: part_of GO:0060919 ! auxin influx + +[Term] +id: GO:0010329 +name: auxin efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of auxin, from one side of a membrane to the other, out of a cell." [PMID:16839804] +synonym: "auxin efflux carrier" RELATED [] +synonym: "auxin efflux facilitator" RELATED [] +is_a: GO:0080161 ! auxin transmembrane transporter activity +relationship: part_of GO:0010315 ! auxin efflux + +[Term] +id: GO:0010330 +name: cellulose synthase complex +namespace: cellular_component +def: "A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall." [PMID:12514238, PMID:18485800, PMID:21307367] +synonym: "CESA complex" EXACT [] +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0010331 +name: gibberellin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth." [GOC:tair_curators] +synonym: "gibberellic acid receptor" RELATED [] +synonym: "gibberellin receptor" RELATED [] +is_a: GO:0019840 ! isoprenoid binding +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0010332 +name: response to gamma radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." [GOC:tair_curators] +synonym: "response to gamma ray" RELATED [] +synonym: "response to gamma-ray photon" RELATED [] +is_a: GO:0010212 ! response to ionizing radiation + +[Term] +id: GO:0010333 +name: terpene synthase activity +namespace: molecular_function +def: "Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units." [EC:4.2.3.-, GOC:tair_curators] +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0010334 +name: sesquiterpene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons." [EC:4.2.3.-, GOC:tair_curators] +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0010335 +name: response to non-ionic osmotic stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment." [GOC:tair_curators] +is_a: GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0010336 +name: gibberellic acid homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation." [PMID:17194763] +synonym: "gibberellin homeostasis" BROAD [] +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0010337 +name: regulation of salicylic acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid." [PMID:14765119] +synonym: "regulation of salicylic acid metabolism" RELATED [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009696 ! salicylic acid metabolic process +relationship: regulates GO:0009696 ! salicylic acid metabolic process + +[Term] +id: GO:0010338 +name: leaf formation +namespace: biological_process +def: "The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts." [GOC:tair_curators] +is_a: GO:0099402 ! plant organ development +is_a: GO:1905393 ! plant organ formation +relationship: part_of GO:0009965 ! leaf morphogenesis + +[Term] +id: GO:0010339 +name: external side of cell wall +namespace: cellular_component +def: "The side of the cell wall that is opposite to the side that faces the cell and its contents." [GOC:mtg_sensu, GOC:tb] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005618 ! cell wall +relationship: part_of GO:0009986 ! cell surface + +[Term] +id: GO:0010340 +name: carboxyl-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester." [PMID:17220201] +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0010341 +name: gibberellin carboxyl-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester." [PMID:17220201] +is_a: GO:0010340 ! carboxyl-O-methyltransferase activity + +[Term] +id: GO:0010342 +name: endosperm cellularization +namespace: biological_process +def: "The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization." [PMID:12421698] +synonym: "cellularization of endosperm" EXACT [] +is_a: GO:0007349 ! cellularization + +[Term] +id: GO:0010343 +name: singlet oxygen-mediated programmed cell death +namespace: biological_process +def: "Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes." [GOC:mtg_apoptosis, PMID:17075038] +synonym: "light-dependent programmed cell death" BROAD [] +synonym: "programmed cell death in response to singlet oxygen" EXACT [] +is_a: GO:0097468 ! programmed cell death in response to reactive oxygen species +relationship: part_of GO:0071452 ! cellular response to singlet oxygen + +[Term] +id: GO:0010344 +name: seed oilbody biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination." [GOC:jl, PMID:16877495] +synonym: "oleosome biogenesis" RELATED [] +synonym: "seed oil body organization" EXACT [] +synonym: "spherosome biogenesis" RELATED [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0044085 ! cellular component biogenesis +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0010345 +name: suberin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols." [PMID:17259262] +xref: MetaCyc:PWY-1121 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process + +[Term] +id: GO:0010346 +name: shoot axis formation +namespace: biological_process +def: "The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts." [GOC:tb] +synonym: "shoot formation" RELATED [] +is_a: GO:1905393 ! plant organ formation +relationship: part_of GO:0010016 ! shoot system morphogenesis + +[Term] +id: GO:0010347 +name: L-galactose-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate." [PMID:15550539, PMID:16595667] +xref: MetaCyc:RXNQT-4142 +is_a: GO:0070456 ! galactose-1-phosphate phosphatase activity + +[Term] +id: GO:0010348 +name: lithium:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in)." [PMID:17270011] +synonym: "lithium:hydrogen antiporter activity" EXACT [] +is_a: GO:0005451 ! monovalent cation:proton antiporter activity +is_a: GO:0046873 ! metal ion transmembrane transporter activity + +[Term] +id: GO:0010349 +name: L-galactose dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+." [PMID:12047629] +synonym: "L-galactose 1-dehydrogenase activity" RELATED [] +xref: MetaCyc:RXN-1884 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0010350 +name: cellular response to magnesium starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium." [PMID:17270009] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0010351 +name: lithium ion transport +namespace: biological_process +def: "The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [PMID:17270011] +synonym: "lithium transport" EXACT [] +is_a: GO:0015672 ! monovalent inorganic cation transport +is_a: GO:0030001 ! metal ion transport + +[Term] +id: GO:0010352 +name: lithium ion export across the plasma membrane +namespace: biological_process +def: "The directed movement of lithium ion out of a cell or organelle." [PMID:17270011] +synonym: "lithium export" EXACT [] +synonym: "lithium ion efflux" RELATED [] +synonym: "lithium ion export" RELATED [] +is_a: GO:0010351 ! lithium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +is_a: GO:0140115 ! export across plasma membrane + +[Term] +id: GO:0010353 +name: response to trehalose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus." [PMID:17031512] +synonym: "response to trehalose stimulus" EXACT [GOC:dos] +is_a: GO:0034285 ! response to disaccharide + +[Term] +id: GO:0010354 +name: homogentisate prenyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid." [PMID:16989822] +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0010355 +name: homogentisate farnesyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol." [PMID:16989822] +is_a: GO:0010354 ! homogentisate prenyltransferase activity + +[Term] +id: GO:0010356 +name: homogentisate geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol." [PMID:16989822] +is_a: GO:0010354 ! homogentisate prenyltransferase activity + +[Term] +id: GO:0010357 +name: homogentisate solanesyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate." [PMID:16989822] +is_a: GO:0010354 ! homogentisate prenyltransferase activity + +[Term] +id: GO:0010358 +name: leaf shaping +namespace: biological_process +def: "The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed." [GOC:tb, PMID:16971475] +synonym: "leaf structural organization" RELATED [] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0009965 ! leaf morphogenesis + +[Term] +id: GO:0010359 +name: regulation of anion channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anion channel activity." [PMID:17319842] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005253 ! anion channel activity +relationship: regulates GO:0005253 ! anion channel activity + +[Term] +id: GO:0010360 +name: negative regulation of anion channel activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity." [PMID:17319842] +is_a: GO:0010359 ! regulation of anion channel activity +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005253 ! anion channel activity +relationship: negatively_regulates GO:0005253 ! anion channel activity + +[Term] +id: GO:0010361 +name: regulation of anion channel activity by blue light +namespace: biological_process +def: "Any process in which blue light modulates the frequency, rate or extent of anion channel activity." [GOC:dph, GOC:tb, PMID:17319842] +synonym: "regulation by blue light of anion channel activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010359 ! regulation of anion channel activity + +[Term] +id: GO:0010362 +name: negative regulation of anion channel activity by blue light +namespace: biological_process +def: "Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity." [PMID:17319842] +synonym: "inhibition by blue light of anion channel activity" NARROW [] +synonym: "negative regulation by blue light of anion channel activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010360 ! negative regulation of anion channel activity +is_a: GO:0010361 ! regulation of anion channel activity by blue light + +[Term] +id: GO:0010363 +name: regulation of plant-type hypersensitive response +namespace: biological_process +def: "Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response." [PMID:16255244] +comment: Note that term is to be used to annotate gene products in the plant. To annotate genes in a symbiont, consider the biological process term 'modulation by symbiont of host programmed cell death ; GO:0052040'. +synonym: "regulation of HR" EXACT [] +synonym: "regulation of HR-PCD" EXACT [] +synonym: "regulation of plant hypersensitive response" EXACT [] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009626 ! plant-type hypersensitive response +relationship: regulates GO:0009626 ! plant-type hypersensitive response + +[Term] +id: GO:0010364 +name: regulation of ethylene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process." [GOC:tair_curators] +is_a: GO:0031335 ! regulation of sulfur amino acid metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009693 ! ethylene biosynthetic process +relationship: regulates GO:0009693 ! ethylene biosynthetic process + +[Term] +id: GO:0010365 +name: positive regulation of ethylene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process." [GOC:tair_curators] +is_a: GO:0010364 ! regulation of ethylene biosynthetic process +is_a: GO:0031337 ! positive regulation of sulfur amino acid metabolic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009693 ! ethylene biosynthetic process +relationship: positively_regulates GO:0009693 ! ethylene biosynthetic process + +[Term] +id: GO:0010366 +name: negative regulation of ethylene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process." [GOC:tair_curators] +is_a: GO:0010364 ! regulation of ethylene biosynthetic process +is_a: GO:0031336 ! negative regulation of sulfur amino acid metabolic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009693 ! ethylene biosynthetic process +relationship: negatively_regulates GO:0009693 ! ethylene biosynthetic process + +[Term] +id: GO:0010367 +name: extracellular isoamylase complex +namespace: cellular_component +def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space." [GOC:tair_curators] +is_a: GO:0043033 ! isoamylase complex +intersection_of: GO:0043033 ! isoamylase complex +intersection_of: part_of GO:0005576 ! extracellular region +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0010368 +name: chloroplast isoamylase complex +namespace: cellular_component +def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized." [GOC:tair_curators] +is_a: GO:0043033 ! isoamylase complex +intersection_of: GO:0043033 ! isoamylase complex +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0010369 +name: chromocenter +namespace: cellular_component +def: "A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure." [PMID:12384572, PMID:15053486, PMID:16831888] +is_a: GO:0098687 ! chromosomal region + +[Term] +id: GO:0010370 +name: perinucleolar chromocenter +namespace: cellular_component +def: "A chromocenter adjacent to the nucleolus." [PMID:15805479] +is_a: GO:0010369 ! chromocenter + +[Term] +id: GO:0010371 +name: regulation of gibberellin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] +synonym: "regulation of gibberellic acid biosynthetic process" NARROW [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009686 ! gibberellin biosynthetic process +relationship: regulates GO:0009686 ! gibberellin biosynthetic process + +[Term] +id: GO:0010372 +name: positive regulation of gibberellin biosynthetic process +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] +synonym: "positive regulation of gibberellic acid biosynthetic process" NARROW [] +is_a: GO:0010371 ! regulation of gibberellin biosynthetic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009686 ! gibberellin biosynthetic process +relationship: positively_regulates GO:0009686 ! gibberellin biosynthetic process + +[Term] +id: GO:0010373 +name: negative regulation of gibberellin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] +synonym: "negative regulation of gibberellic acid biosynthetic process" NARROW [] +is_a: GO:0010371 ! regulation of gibberellin biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009686 ! gibberellin biosynthetic process +relationship: negatively_regulates GO:0009686 ! gibberellin biosynthetic process + +[Term] +id: GO:0010374 +name: stomatal complex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells." [PMID:17259259] +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0090558 ! plant epidermis development + +[Term] +id: GO:0010375 +name: stomatal complex patterning +namespace: biological_process +def: "The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells." [PMID:17259259] +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0010376 +name: stomatal complex formation +namespace: biological_process +def: "The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells." [PMID:17259259] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0010103 ! stomatal complex morphogenesis + +[Term] +id: GO:0010377 +name: guard cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere." [PMID:17259259] +synonym: "stomatal cell fate commitment" RELATED [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0010052 ! guard cell differentiation + +[Term] +id: GO:0010378 +name: temperature compensation of the circadian clock +namespace: biological_process +def: "The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms." [PMID:16617099] +synonym: "regulation of the circadian clock by temperature" RELATED [] +is_a: GO:0009266 ! response to temperature stimulus +is_a: GO:0042752 ! regulation of circadian rhythm + +[Term] +id: GO:0010379 +name: phaseic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA)." [BioCyc:PWY-5271] +xref: MetaCyc:PWY-5271 +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0043289 ! apocarotenoid biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0010380 +name: regulation of chlorophyll biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors." [PMID:17291312] +is_a: GO:0090056 ! regulation of chlorophyll metabolic process +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015995 ! chlorophyll biosynthetic process +relationship: regulates GO:0015995 ! chlorophyll biosynthetic process +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0010381 +name: peroxisome-chloroplast membrane tethering +namespace: biological_process +def: "The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles." [PMID:17215364] +synonym: "attachment of peroxisome to chloroplast" EXACT [] +is_a: GO:0140056 ! organelle localization by membrane tethering +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0010383 +name: cell wall polysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cell wall polysaccharides." [GOC:tair_curators] +is_a: GO:0044036 ! cell wall macromolecule metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0010384 +name: cell wall proteoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates." [GOC:tair_curators] +synonym: "cell wall proteoglycan metabolism" EXACT [] +is_a: GO:0006029 ! proteoglycan metabolic process +is_a: GO:0044036 ! cell wall macromolecule metabolic process + +[Term] +id: GO:0010385 +name: double-stranded methylated DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks." [GOC:imk, PMID:17242155] +is_a: GO:0003690 ! double-stranded DNA binding + +[Term] +id: GO:0010387 +name: COP9 signalosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome." [PMID:17307927] +synonym: "signalosome assembly" BROAD [GOC:krc] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0010389 +name: regulation of G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." [GOC:mtg_cell_cycle, PMID:17329565] +synonym: "regulation of mitotic entry" EXACT [GOC:vw] +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +is_a: GO:1902749 ! regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000086 ! G2/M transition of mitotic cell cycle +relationship: regulates GO:0000086 ! G2/M transition of mitotic cell cycle + +[Term] +id: GO:0010390 +name: histone monoubiquitination +namespace: biological_process +def: "The modification of histones by addition of a single ubiquitin group." [PMID:17329563] +is_a: GO:0006513 ! protein monoubiquitination +is_a: GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0010391 +name: glucomannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units." [GOC:tair_curators] +synonym: "glucomannan metabolism" EXACT [] +is_a: GO:0006080 ! substituted mannan metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0010392 +name: galactoglucomannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units." [GOC:tair_curators] +synonym: "galactoglucomannan metabolism" RELATED [] +is_a: GO:0006080 ! substituted mannan metabolic process + +[Term] +id: GO:0010393 +name: galacturonan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues." [GOC:tair_curators] +synonym: "galacturonan metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0010394 +name: homogalacturonan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3." [GOC:tair_curators] +synonym: "homogalacturonan metabolism" EXACT [] +is_a: GO:0010393 ! galacturonan metabolic process + +[Term] +id: GO:0010395 +name: rhamnogalacturonan I metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone." [GOC:tair_curators] +synonym: "RGI metabolism" RELATED [] +synonym: "rhamnogalacturonan I metabolism" EXACT [] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process +is_a: GO:0052546 ! cell wall pectin metabolic process + +[Term] +id: GO:0010396 +name: rhamnogalacturonan II metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues." [GOC:tair_curators] +synonym: "rhamnogalacturonan II metabolism" EXACT [] +is_a: GO:0010393 ! galacturonan metabolic process + +[Term] +id: GO:0010397 +name: apiogalacturonan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links." [GOC:tair_curators] +synonym: "apiogalacturonan metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0010398 +name: xylogalacturonan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues." [GOC:tair_curators] +synonym: "xylogalacturonan metabolism" EXACT [] +is_a: GO:0010393 ! galacturonan metabolic process + +[Term] +id: GO:0010399 +name: rhamnogalacturonan I backbone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone." [GOC:tair_curators] +synonym: "rhamnogalacturonan I backbone metabolism" EXACT [] +is_a: GO:0010395 ! rhamnogalacturonan I metabolic process + +[Term] +id: GO:0010400 +name: rhamnogalacturonan I side chain metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I." [GOC:tair_curators] +synonym: "rhamnogalacturonan I side chain metabolism" EXACT [] +is_a: GO:0010395 ! rhamnogalacturonan I metabolic process + +[Term] +id: GO:0010401 +name: pectic galactan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I." [GOC:tair_curators] +synonym: "pectic galactan metabolism" EXACT [] +is_a: GO:0010400 ! rhamnogalacturonan I side chain metabolic process + +[Term] +id: GO:0010402 +name: pectic arabinan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I." [GOC:tair_curators] +synonym: "pectic arabinan metabolism" EXACT [] +is_a: GO:0010400 ! rhamnogalacturonan I side chain metabolic process + +[Term] +id: GO:0010403 +name: pectic arabinogalactan I metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I." [GOC:tair_curators] +synonym: "pectic arabinogalactan I metabolism" EXACT [] +is_a: GO:0010400 ! rhamnogalacturonan I side chain metabolic process + +[Term] +id: GO:0010404 +name: cell wall hydroxyproline-rich glycoprotein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates." [GOC:tair_curators] +synonym: "cell wall hydroxyproline-rich glycoprotein metabolism" EXACT [] +is_a: GO:0010384 ! cell wall proteoglycan metabolic process + +[Term] +id: GO:0010405 +name: arabinogalactan protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures." [GOC:tair_curators] +synonym: "arabinogalactan protein metabolism" EXACT [] +is_a: GO:0010404 ! cell wall hydroxyproline-rich glycoprotein metabolic process + +[Term] +id: GO:0010406 +name: classical arabinogalactan protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored." [GOC:tair_curators] +synonym: "classical-arabinogalactan protein metabolism" EXACT [] +is_a: GO:0010405 ! arabinogalactan protein metabolic process + +[Term] +id: GO:0010407 +name: non-classical arabinogalactan protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains." [GOC:tair_curators] +synonym: "non-classical arabinogalactan protein metabolism" EXACT [] +is_a: GO:0010405 ! arabinogalactan protein metabolic process + +[Term] +id: GO:0010408 +name: fasciclin-like arabinogalactan protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain." [GOC:tair_curators] +synonym: "fasciclin-like arabinogalactan protein metabolism" EXACT [] +is_a: GO:0010405 ! arabinogalactan protein metabolic process + +[Term] +id: GO:0010409 +name: extensin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated." [GOC:tair_curators] +synonym: "extensin metabolism" EXACT [] +is_a: GO:0010404 ! cell wall hydroxyproline-rich glycoprotein metabolic process + +[Term] +id: GO:0010410 +name: hemicellulose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present." [GOC:tair_curators] +synonym: "hemicellulose metabolism" EXACT [] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process + +[Term] +id: GO:0010411 +name: xyloglucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants." [GOC:tair_curators] +synonym: "xyloglucan metabolism" EXACT [GOC:obol] +is_a: GO:0006073 ! cellular glucan metabolic process +is_a: GO:0010410 ! hemicellulose metabolic process + +[Term] +id: GO:0010412 +name: mannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units." [GOC:tair_curators] +synonym: "mannan metabolism" EXACT [] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process + +[Term] +id: GO:0010413 +name: glucuronoxylan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units." [GOC:tair_curators] +synonym: "glucuronoxylan metabolism" EXACT [] +is_a: GO:0045491 ! xylan metabolic process + +[Term] +id: GO:0010414 +name: glucuronoarabinoxylan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units." [GOC:tair_curators] +synonym: "glucuronoarabinoxylan metabolism" EXACT [] +is_a: GO:0010413 ! glucuronoxylan metabolic process +is_a: GO:0010416 ! arabinoxylan-containing compound metabolic process + +[Term] +id: GO:0010415 +name: unsubstituted mannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units." [GOC:tair_curators] +synonym: "unsubstituted mannan metabolism" EXACT [] +is_a: GO:0010412 ! mannan metabolic process + +[Term] +id: GO:0010416 +name: arabinoxylan-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units." [GOC:tair_curators] +synonym: "arabinoxylan metabolic process" RELATED [] +synonym: "arabinoxylan metabolism" RELATED [] +is_a: GO:0045491 ! xylan metabolic process + +[Term] +id: GO:0010417 +name: glucuronoxylan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues." [GOC:tair_curators] +synonym: "glucuronoxylan anabolism" EXACT [] +synonym: "glucuronoxylan biosynthesis" EXACT [] +synonym: "glucuronoxylan formation" EXACT [] +synonym: "glucuronoxylan synthesis" EXACT [] +is_a: GO:0010413 ! glucuronoxylan metabolic process +is_a: GO:0045492 ! xylan biosynthetic process + +[Term] +id: GO:0010418 +name: rhamnogalacturonan II backbone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues." [GOC:tair_curators] +synonym: "rhamnogalacturonan II backbone metabolism" EXACT [] +is_a: GO:0010394 ! homogalacturonan metabolic process +is_a: GO:0010396 ! rhamnogalacturonan II metabolic process + +[Term] +id: GO:0010419 +name: rhamnogalacturonan II side chain metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively." [GOC:tair_curators] +synonym: "rhamnogalacturonan II side chain metabolism" EXACT [] +is_a: GO:0010396 ! rhamnogalacturonan II metabolic process + +[Term] +id: GO:0010420 +name: 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity +namespace: molecular_function +alt_id: GO:1990886 +def: "Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+." [PMID:10419476, PMID:9628017, RHEA:44452] +synonym: "polyprenyldihydroxybenzoate methyltransferase activity" RELATED [] +xref: EC:2.1.1.114 +xref: MetaCyc:RXN-9281 +xref: RHEA:44452 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: sl +creation_date: 2015-10-28T22:12:58Z + +[Term] +id: GO:0010421 +name: hydrogen peroxide-mediated programmed cell death +namespace: biological_process +def: "Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes." [GOC:mtg_apoptosis, PMID:16036580] +synonym: "programmed cell death in response to hydrogen peroxide" EXACT [] +is_a: GO:0036474 ! cell death in response to hydrogen peroxide +is_a: GO:0097468 ! programmed cell death in response to reactive oxygen species + +[Term] +id: GO:0010422 +name: regulation of brassinosteroid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids." [PMID:16857903] +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016132 ! brassinosteroid biosynthetic process +relationship: regulates GO:0016132 ! brassinosteroid biosynthetic process + +[Term] +id: GO:0010423 +name: negative regulation of brassinosteroid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids." [PMID:16857903] +is_a: GO:0010422 ! regulation of brassinosteroid biosynthetic process +is_a: GO:0090032 ! negative regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016132 ! brassinosteroid biosynthetic process +relationship: negatively_regulates GO:0016132 ! brassinosteroid biosynthetic process + +[Term] +id: GO:0010424 +name: DNA methylation on cytosine within a CG sequence +namespace: biological_process +def: "The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule." [GOC:dph, GOC:tb, PMID:17239600] +synonym: "cytosine methylation within a CG sequence" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032776 ! DNA methylation on cytosine + +[Term] +id: GO:0010425 +name: DNA methylation on cytosine within a CNG sequence +namespace: biological_process +def: "The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide." [GOC:dph, GOC:tb, PMID:17239600] +synonym: "cytosine methylation within a CNG sequence" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032776 ! DNA methylation on cytosine + +[Term] +id: GO:0010426 +name: DNA methylation on cytosine within a CHH sequence +namespace: biological_process +def: "The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide." [GOC:dph, GOC:mah, GOC:tb, PMID:15861207, PMID:17239600] +synonym: "cytosine methylation within a CHH sequence" EXACT [GOC:mah] +synonym: "cytosine methylation within a CNN sequence" EXACT [GOC:dph, GOC:tb] +synonym: "DNA methylation on cytosine within a CNN sequence" EXACT [GOC:mah] +is_a: GO:0032776 ! DNA methylation on cytosine + +[Term] +id: GO:0010427 +name: abscisic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with abscisic acid, plant hormones that regulate aspects of plant growth." [PMID:17347412] +synonym: "ABA binding" RELATED [] +synonym: "abscisate binding" RELATED [] +is_a: GO:0019840 ! isoprenoid binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0010428 +name: methyl-CpNpG binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide." [PMID:17239600] +is_a: GO:0000166 ! nucleotide binding + +[Term] +id: GO:0010429 +name: methyl-CpNpN binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide." [PMID:17239600] +is_a: GO:0000166 ! nucleotide binding + +[Term] +id: GO:0010430 +name: fatty acid omega-oxidation +namespace: biological_process +def: "A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation." [MetaCyc:PWY-2724, PMID:16404574] +xref: MetaCyc:PWY-2724 +is_a: GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0010431 +name: seed maturation +namespace: biological_process +def: "A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination." [PMID:16096971] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048609 ! multicellular organismal reproductive process +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0010432 +name: bract development +namespace: biological_process +def: "The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence." [GOC:tb, PMID:16554366, PO:0009055] +is_a: GO:0048827 ! phyllome development + +[Term] +id: GO:0010433 +name: bract morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence." [GOC:tb, PMID:16554366, PO:0009055] +is_a: GO:1905392 ! plant organ morphogenesis +relationship: part_of GO:0010432 ! bract development + +[Term] +id: GO:0010434 +name: bract formation +namespace: biological_process +def: "The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence." [GOC:tb, PMID:16554366, PO:0009055] +is_a: GO:1905393 ! plant organ formation +relationship: part_of GO:0010433 ! bract morphogenesis + +[Term] +id: GO:0010435 +name: 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0." [PMID:16963437] +synonym: "3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity" EXACT [MetaCyc:RXN-10695] +synonym: "3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity" EXACT [] +synonym: "OPC-8:0 CoA ligase activity" EXACT [] +xref: EC:6.2.1 +xref: MetaCyc:RXN-10695 +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0010436 +name: carotenoid dioxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative cleavage of carotenoids." [PMID:16459333] +synonym: "carotenoid-cleaving dioxygenase" RELATED [] +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0010437 +name: 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond." [PMID:16459333] +is_a: GO:0010436 ! carotenoid dioxygenase activity + +[Term] +id: GO:0010438 +name: cellular response to sulfur starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur." [PMID:17420480] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0010439 +name: regulation of glucosinolate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae." [PMID:17420480] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019761 ! glucosinolate biosynthetic process +relationship: regulates GO:0019761 ! glucosinolate biosynthetic process + +[Term] +id: GO:0010440 +name: stomatal lineage progression +namespace: biological_process +def: "The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex." [GOC:expert_db, GOC:tb] +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0010374 ! stomatal complex development + +[Term] +id: GO:0010441 +name: guard cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure." [GOC:tb] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0010052 ! guard cell differentiation + +[Term] +id: GO:0010442 +name: guard cell morphogenesis +namespace: biological_process +def: "Generation and organization of the polarized cell that is capable of turgor driven movement." [GOC:expert_db, GOC:tb] +synonym: "guard cell morphogenesis during differentiation" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0010441 ! guard cell development + +[Term] +id: GO:0010443 +name: meristemoid mother cell division +namespace: biological_process +def: "The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC." [GOC:expert_db, GOC:tb] +synonym: "meristemoid division" RELATED [] +is_a: GO:0000911 ! cytokinesis by cell plate formation +relationship: part_of GO:0010440 ! stomatal lineage progression + +[Term] +id: GO:0010444 +name: guard mother cell differentiation +namespace: biological_process +def: "The process in which a meristemoid acquires the specialized features of a guard mother cell." [GOC:expert_db, GOC:tb] +is_a: GO:0090627 ! plant epidermal cell differentiation +relationship: part_of GO:0010440 ! stomatal lineage progression + +[Term] +id: GO:0010445 +name: nuclear dicing body +namespace: cellular_component +def: "A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes." [PMID:17442570] +synonym: "D body" EXACT [] +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0010446 +name: response to alkaline pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:go_curators, GOC:tb, Wikipedia:PH] +synonym: "response to alkalinity" BROAD [] +synonym: "response to basic pH" EXACT [] +is_a: GO:0009268 ! response to pH + +[Term] +id: GO:0010447 +name: response to acidic pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:go_curators, GOC:tb, Wikipedia:PH] +comment: This term should be used to annotate instances where a cell or organism is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0001101 'response to acid chemical'. +synonym: "response to acidity" BROAD [] +is_a: GO:0009268 ! response to pH + +[Term] +id: GO:0010448 +name: vegetative meristem growth +namespace: biological_process +def: "The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia." [GOC:tb, ISBN:0849397928] +is_a: GO:0035266 ! meristem growth +is_a: GO:0080186 ! developmental vegetative growth +relationship: part_of GO:0048367 ! shoot system development + +[Term] +id: GO:0010449 +name: root meristem growth +namespace: biological_process +def: "The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root." [GOC:tb] +is_a: GO:0035266 ! meristem growth +relationship: part_of GO:0048364 ! root development + +[Term] +id: GO:0010450 +name: inflorescence meristem growth +namespace: biological_process +def: "The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0035266 ! meristem growth +relationship: part_of GO:0010229 ! inflorescence development + +[Term] +id: GO:0010451 +name: floral meristem growth +namespace: biological_process +def: "The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0035266 ! meristem growth +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0010452 +name: histone H3-K36 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone." [GOC:pr, GOC:tb] +synonym: "histone H3 K36 methylation" EXACT [GOC:tb] +synonym: "histone H3K36me" EXACT [GOC:tb] +synonym: "histone lysine H3 K36 methylation" EXACT [GOC:tb] +is_a: GO:0034968 ! histone lysine methylation + +[Term] +id: GO:0010453 +name: regulation of cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045165 ! cell fate commitment +relationship: regulates GO:0045165 ! cell fate commitment + +[Term] +id: GO:0010454 +name: negative regulation of cell fate commitment +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0045596 ! negative regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045165 ! cell fate commitment +relationship: negatively_regulates GO:0045165 ! cell fate commitment + +[Term] +id: GO:0010455 +name: positive regulation of cell fate commitment +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0045597 ! positive regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045165 ! cell fate commitment +relationship: positively_regulates GO:0045165 ! cell fate commitment + +[Term] +id: GO:0010456 +name: cell proliferation in dorsal spinal cord +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population." [GOC:dph, GOC:tb] +is_a: GO:0061351 ! neural precursor cell proliferation + +[Term] +id: GO:0010457 +name: centriole-centriole cohesion +namespace: biological_process +def: "The cell cycle process in which the two centrioles within a centrosome remain tightly paired." [GOC:dph, GOC:tb] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007098 ! centrosome cycle + +[Term] +id: GO:0010458 +name: exit from mitosis +namespace: biological_process +def: "The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] +synonym: "exit from mitotic division" EXACT [] +synonym: "mitotic exit" EXACT [] +is_a: GO:0044772 ! mitotic cell cycle phase transition +relationship: part_of GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0010459 +name: negative regulation of heart rate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency or rate of heart contraction." [GOC:dph, GOC:tb] +is_a: GO:0002027 ! regulation of heart rate +is_a: GO:0045822 ! negative regulation of heart contraction + +[Term] +id: GO:0010460 +name: positive regulation of heart rate +namespace: biological_process +def: "Any process that activates or increases the frequency or rate of heart contraction." [GOC:dph, GOC:tb] +is_a: GO:0002027 ! regulation of heart rate +is_a: GO:0045823 ! positive regulation of heart contraction + +[Term] +id: GO:0010461 +name: light-activated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus." [GOC:dph, GOC:tb] +is_a: GO:0005216 ! ion channel activity + +[Term] +id: GO:0010462 +name: regulation of light-activated voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity." [GOC:dph, GOC:tb] +is_a: GO:0016061 ! regulation of light-activated channel activity +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008086 ! light-activated voltage-gated calcium channel activity +relationship: regulates GO:0008086 ! light-activated voltage-gated calcium channel activity + +[Term] +id: GO:0010463 +name: mesenchymal cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0010464 +name: regulation of mesenchymal cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010463 ! mesenchymal cell proliferation +relationship: regulates GO:0010463 ! mesenchymal cell proliferation + +[Term] +id: GO:0010465 +name: nerve growth factor receptor activity +namespace: molecular_function +def: "Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity." [GOC:dph, GOC:tb] +synonym: "beta-nerve growth factor receptor activity" EXACT [PR:000011194] +synonym: "NGF receptor activity" EXACT [PR:000011194] +is_a: GO:0005030 ! neurotrophin receptor activity +relationship: has_part GO:0048406 ! nerve growth factor binding +relationship: part_of GO:0038180 ! nerve growth factor signaling pathway + +[Term] +id: GO:0010466 +name: negative regulation of peptidase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008233 ! peptidase activity +relationship: negatively_regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0010467 +name: gene expression +namespace: biological_process +def: "The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] +subset: goslim_flybase_ribbon +xref: Wikipedia:Gene_expression +is_a: GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0010468 +name: regulation of gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] +comment: This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. +synonym: "regulation of gene product expression" RELATED [] +synonym: "regulation of protein expression" NARROW [] +xref: Wikipedia:Regulation_of_gene_expression +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010467 ! gene expression +relationship: regulates GO:0010467 ! gene expression + +[Term] +id: GO:0010469 +name: regulation of signaling receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity." [GOC:dph, GOC:tb] +synonym: "regulation of receptor activity" BROAD [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038023 ! signaling receptor activity +relationship: regulates GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0010470 +name: regulation of gastrulation +namespace: biological_process +def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007369 ! gastrulation +relationship: regulates GO:0007369 ! gastrulation + +[Term] +id: GO:0010471 +name: GDP-galactose:mannose-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate." [MetaCyc:RXN4FS-12, PMID:17485667] +synonym: "GDP-L-galactose phosphorylase activity" BROAD [MetaCyc:AT4G26850-MONOMER] +synonym: "GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity" EXACT [MetaCyc:RXN4FS-12] +xref: MetaCyc:RXN4FS-12 +is_a: GO:0008905 ! mannose-phosphate guanylyltransferase activity + +[Term] +id: GO:0010472 +name: GDP-galactose:glucose-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose." [MetaCyc:RXN4FS-13, PMID:17485667] +synonym: "GDP-L-galactose phosphorylase activity" BROAD [MetaCyc:AT4G26850-MONOMER] +synonym: "GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity" EXACT [MetaCyc:RXN4FS-13] +xref: MetaCyc:RXN4FS-13 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0010473 +name: GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol." [PMID:17485667] +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0010474 +name: glucose-1-phosphate guanylyltransferase (GDP) activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose." [PMID:17462988] +synonym: "GDP:glucose-1-phosphate guanyltransferase activity" EXACT [] +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0010475 +name: galactose-1-phosphate guanylyltransferase (GDP) activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose." [PMID:17462988] +synonym: "GDP:galactose-1-phosphate guanyltransferase activity" EXACT [] +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0010476 +name: gibberellin mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of gibberellin stimulus." [PMID:17521411] +synonym: "gibberellin-mediated signalling" EXACT [GOC:mah] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071370 ! cellular response to gibberellin stimulus + +[Term] +id: GO:0010477 +name: response to sulfur dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus." [PMID:17425719] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0010478 +name: chlororespiration +namespace: biological_process +def: "A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool." [GOC:mtg_electron_transport, GOC:tb, PMID:17573537] +is_a: GO:0022904 ! respiratory electron transport chain + +[Term] +id: GO:0010479 +name: stele development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds." [GOC:tb] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0048364 ! root development + +[Term] +id: GO:0010480 +name: microsporocyte differentiation +namespace: biological_process +def: "The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell." [CL:0000248, PMID:16751349] +synonym: "pollen mother cell differentiation" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048533 ! sporocyte differentiation +relationship: part_of GO:0048653 ! anther development + +[Term] +id: GO:0010481 +name: epidermal cell division +namespace: biological_process +def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] +synonym: "hypodermal cell division" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0010482 +name: regulation of epidermal cell division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] +synonym: "regulation of hypodermal cell division" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010481 ! epidermal cell division +relationship: regulates GO:0010481 ! epidermal cell division + +[Term] +id: GO:0010483 +name: pollen tube reception +namespace: biological_process +def: "Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells." [GOC:tb, PMID:17673660] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051703 ! intraspecies interaction between organisms +relationship: part_of GO:0009856 ! pollination + +[Term] +id: GO:0010484 +name: H3 histone acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3." [EC:2.3.1.48] +is_a: GO:0004402 ! histone acetyltransferase activity +relationship: part_of GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0010485 +name: H4 histone acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4." [EC:2.3.1.48] +is_a: GO:0004402 ! histone acetyltransferase activity +relationship: part_of GO:0043967 ! histone H4 acetylation + +[Term] +id: GO:0010486 +name: manganese:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in)." [PMID:17559518] +synonym: "manganese:hydrogen antiporter activity" EXACT [] +is_a: GO:0005384 ! manganese ion transmembrane transporter activity +is_a: GO:0015078 ! proton transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0010487 +name: thermospermine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+." [EC:2.5.1.79, MetaCyc:RXN-11190, PMID:17560575] +xref: EC:2.5.1.79 +xref: MetaCyc:RXN-11190 +xref: RHEA:30515 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0010488 +name: UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP." [PMID:17630273] +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0010489 +name: UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose." [GOC:tair_curators, PMID:17190829] +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0010490 +name: UDP-4-keto-rhamnose-4-keto-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+." [GOC:tair_curators, PMID:17190829] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0010491 +name: UTP:arabinose-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate." [PMID:17341835] +is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity + +[Term] +id: GO:0010492 +name: maintenance of shoot apical meristem identity +namespace: biological_process +def: "The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:dph, GOC:tb, PMID:17461786] +is_a: GO:0010074 ! maintenance of meristem identity + +[Term] +id: GO:0010493 +name: Lewis a epitope biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides." [PMID:17630273] +synonym: "LE A biosynthetic process" RELATED [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0010494 +name: cytoplasmic stress granule +namespace: cellular_component +def: "A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress." [GOC:ans, PMID:17284590, PMID:17601829, PMID:17967451, PMID:20368989] +synonym: "cytoplasmic mRNP granule" EXACT [] +synonym: "stress granule" EXACT [] +xref: Wikipedia:Stress_granule +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule + +[Term] +id: GO:0010495 +name: long-distance posttranscriptional gene silencing +namespace: biological_process +def: "A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place." [GOC:dph, GOC:tb, PMID:11590235, PMID:17785412] +synonym: "long-distance propagation of posttranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] +is_a: GO:0016441 ! posttranscriptional gene silencing + +[Term] +id: GO:0010496 +name: intercellular transport +namespace: biological_process +alt_id: GO:1902585 +def: "The movement of substances between cells." [GOC:dhl] +synonym: "single organism intercellular transport" RELATED [GOC:TermGenie] +synonym: "single-organism intercellular transport" RELATED [] +is_a: GO:0006810 ! transport +is_a: GO:0009987 ! cellular process +created_by: jl +creation_date: 2013-12-19T13:24:56Z + +[Term] +id: GO:0010497 +name: plasmodesmata-mediated intercellular transport +namespace: biological_process +alt_id: GO:1902587 +def: "The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [PMID:17601829] +synonym: "plasmodesma-mediated cell-to-cell transport" EXACT [] +synonym: "plasmodesma-mediated intercellular transport" EXACT [] +synonym: "plasmodesmata-mediated cell-to-cell transport" EXACT [] +synonym: "single organism plasmodesmata-mediated intercellular transport" RELATED [GOC:TermGenie] +synonym: "single-organism plasmodesmata-mediated intercellular transport" RELATED [] +is_a: GO:0010496 ! intercellular transport +created_by: jl +creation_date: 2013-12-19T13:37:36Z + +[Term] +id: GO:0010498 +name: proteasomal protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome." [GOC:tb] +synonym: "proteasome-mediated protein catabolic process" EXACT [] +synonym: "proteasome-mediated protein catabolism" EXACT [] +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process + +[Term] +id: GO:0010499 +name: proteasomal ubiquitin-independent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin." [GOC:tb] +is_a: GO:0010498 ! proteasomal protein catabolic process + +[Term] +id: GO:0010500 +name: transmitting tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary." [PMID:17855426] +is_a: GO:0048467 ! gynoecium development + +[Term] +id: GO:0010501 +name: RNA secondary structure unwinding +namespace: biological_process +def: "The process in which a secondary structure of RNA are broken or 'melted'." [PMID:17169986] +synonym: "RNA duplex unwinding" EXACT [GOC:ecd] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0010503 +name: obsolete negative regulation of cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed. +is_obsolete: true + +[Term] +id: GO:0010504 +name: obsolete regulation of cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed. +is_obsolete: true + +[Term] +id: GO:0010505 +name: obsolete positive regulation of cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed. +is_obsolete: true + +[Term] +id: GO:0010506 +name: regulation of autophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006914 ! autophagy +relationship: regulates GO:0006914 ! autophagy + +[Term] +id: GO:0010507 +name: negative regulation of autophagy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:0031330 ! negative regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006914 ! autophagy +relationship: negatively_regulates GO:0006914 ! autophagy + +[Term] +id: GO:0010508 +name: positive regulation of autophagy +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:0031331 ! positive regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006914 ! autophagy +relationship: positively_regulates GO:0006914 ! autophagy + +[Term] +id: GO:0010509 +name: polyamine homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of a polyamine." [GOC:dph, GOC:rph, GOC:tb, PMID:11161802, PMID:9761731] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0010510 +name: regulation of acetyl-CoA biosynthetic process from pyruvate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate." [GOC:dph, GOC:tb] +is_a: GO:0050812 ! regulation of acyl-CoA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate +relationship: regulates GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate + +[Term] +id: GO:0010511 +name: regulation of phosphatidylinositol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006661 ! phosphatidylinositol biosynthetic process +relationship: regulates GO:0006661 ! phosphatidylinositol biosynthetic process + +[Term] +id: GO:0010512 +name: negative regulation of phosphatidylinositol biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] +is_a: GO:0010511 ! regulation of phosphatidylinositol biosynthetic process +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006661 ! phosphatidylinositol biosynthetic process +relationship: negatively_regulates GO:0006661 ! phosphatidylinositol biosynthetic process + +[Term] +id: GO:0010513 +name: positive regulation of phosphatidylinositol biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] +is_a: GO:0010511 ! regulation of phosphatidylinositol biosynthetic process +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006661 ! phosphatidylinositol biosynthetic process +relationship: positively_regulates GO:0006661 ! phosphatidylinositol biosynthetic process + +[Term] +id: GO:0010514 +name: induction of conjugation with cellular fusion +namespace: biological_process +def: "The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types." [GOC:dph, GOC:tb] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion + +[Term] +id: GO:0010515 +name: negative regulation of induction of conjugation with cellular fusion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0031138 ! negative regulation of conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010514 ! induction of conjugation with cellular fusion +relationship: negatively_regulates GO:0010514 ! induction of conjugation with cellular fusion + +[Term] +id: GO:0010516 +name: negative regulation of cellular response to nitrogen starvation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation." [GOC:dph, GOC:tb] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006995 ! cellular response to nitrogen starvation +relationship: negatively_regulates GO:0006995 ! cellular response to nitrogen starvation + +[Term] +id: GO:0010517 +name: regulation of phospholipase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0060191 ! regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004620 ! phospholipase activity +relationship: regulates GO:0004620 ! phospholipase activity + +[Term] +id: GO:0010518 +name: positive regulation of phospholipase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010517 ! regulation of phospholipase activity +is_a: GO:0060193 ! positive regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004620 ! phospholipase activity +relationship: positively_regulates GO:0004620 ! phospholipase activity + +[Term] +id: GO:0010519 +name: negative regulation of phospholipase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010517 ! regulation of phospholipase activity +is_a: GO:0060192 ! negative regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004620 ! phospholipase activity +relationship: negatively_regulates GO:0004620 ! phospholipase activity + +[Term] +id: GO:0010520 +name: regulation of reciprocal meiotic recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:0060631 ! regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007131 ! reciprocal meiotic recombination +relationship: regulates GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010521 +name: telomerase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence." [GOC:dph, GOC:krc, GOC:tb] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0003720 ! telomerase activity +relationship: part_of GO:0051974 ! negative regulation of telomerase activity + +[Term] +id: GO:0010522 +name: regulation of calcium ion transport into cytosol +namespace: biological_process +def: "Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:dph, GOC:tb] +is_a: GO:0051924 ! regulation of calcium ion transport +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060402 ! calcium ion transport into cytosol +relationship: regulates GO:0060402 ! calcium ion transport into cytosol + +[Term] +id: GO:0010523 +name: negative regulation of calcium ion transport into cytosol +namespace: biological_process +def: "Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:dph, GOC:tb] +is_a: GO:0010522 ! regulation of calcium ion transport into cytosol +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051926 ! negative regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060402 ! calcium ion transport into cytosol +relationship: negatively_regulates GO:0060402 ! calcium ion transport into cytosol + +[Term] +id: GO:0010524 +name: positive regulation of calcium ion transport into cytosol +namespace: biological_process +def: "Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:dph, GOC:tb] +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +is_a: GO:0010522 ! regulation of calcium ion transport into cytosol +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051928 ! positive regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060402 ! calcium ion transport into cytosol +relationship: positively_regulates GO:0060402 ! calcium ion transport into cytosol + +[Term] +id: GO:0010525 +name: regulation of transposition, RNA-mediated +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] +is_a: GO:0010528 ! regulation of transposition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032197 ! transposition, RNA-mediated +relationship: regulates GO:0032197 ! transposition, RNA-mediated + +[Term] +id: GO:0010526 +name: negative regulation of transposition, RNA-mediated +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] +is_a: GO:0010525 ! regulation of transposition, RNA-mediated +is_a: GO:0010529 ! negative regulation of transposition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032197 ! transposition, RNA-mediated +relationship: negatively_regulates GO:0032197 ! transposition, RNA-mediated + +[Term] +id: GO:0010527 +name: positive regulation of transposition, RNA-mediated +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] +is_a: GO:0010525 ! regulation of transposition, RNA-mediated +is_a: GO:0010530 ! positive regulation of transposition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032197 ! transposition, RNA-mediated +relationship: positively_regulates GO:0032197 ! transposition, RNA-mediated + +[Term] +id: GO:0010528 +name: regulation of transposition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032196 ! transposition +relationship: regulates GO:0032196 ! transposition + +[Term] +id: GO:0010529 +name: negative regulation of transposition +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] +is_a: GO:0010528 ! regulation of transposition +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032196 ! transposition +relationship: negatively_regulates GO:0032196 ! transposition + +[Term] +id: GO:0010530 +name: positive regulation of transposition +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] +is_a: GO:0010528 ! regulation of transposition +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032196 ! transposition +relationship: positively_regulates GO:0032196 ! transposition + +[Term] +id: GO:0010533 +name: regulation of activation of Janus kinase activity +namespace: biological_process +alt_id: GO:0010532 +alt_id: GO:0010534 +def: "Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:17190829, PMID:9135582] +synonym: "regulation of activation of JAK protein" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of activation of JAK1 kinase activity" NARROW [] +synonym: "regulation of activation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "regulation of activation of JAK2 kinase activity" NARROW [] +synonym: "regulation of activation of JAK2 protein" NARROW [GOC:dph, GOC:tb] +synonym: "regulation of tyrosine phosphorylation of JAK protein" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of tyrosine phosphorylation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "regulation of tyrosine phosphorylation of JAK2 protein" NARROW [GOC:dph, GOC:tb] +is_a: GO:0045859 ! regulation of protein kinase activity +is_a: GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042976 ! activation of Janus kinase activity +relationship: regulates GO:0042976 ! activation of Janus kinase activity + +[Term] +id: GO:0010536 +name: positive regulation of activation of Janus kinase activity +namespace: biological_process +alt_id: GO:0010535 +alt_id: GO:0010537 +def: "Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] +synonym: "positive regulation of activation of JAK protein" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of activation of JAK1 kinase activity" NARROW [] +synonym: "positive regulation of activation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of activation of JAK2 kinase activity" NARROW [] +synonym: "positive regulation of activation of JAK2 protein" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of tyrosine phosphorylation of JAK protein" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of tyrosine phosphorylation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of tyrosine phosphorylation of JAK2 protein" NARROW [GOC:dph, GOC:tb] +is_a: GO:0010533 ! regulation of activation of Janus kinase activity +is_a: GO:0045860 ! positive regulation of protein kinase activity +is_a: GO:0046427 ! positive regulation of receptor signaling pathway via JAK-STAT +is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042976 ! activation of Janus kinase activity +relationship: positively_regulates GO:0042976 ! activation of Janus kinase activity + +[Term] +id: GO:0010538 +name: obsolete Hsp27 protein regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone." [GOC:dph, GOC:tb, PMID:11546764] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'. +synonym: "Hsp27 protein regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051008 +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0010539 +name: obsolete Hsp27 protein inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'. +synonym: "Hsp27 protein inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051008 +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0010540 +name: basipetal auxin transport +namespace: biological_process +def: "The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root." [PMID:10677441] +is_a: GO:0009926 ! auxin polar transport + +[Term] +id: GO:0010541 +name: acropetal auxin transport +namespace: biological_process +def: "The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root." [PMID:10677441] +is_a: GO:0009926 ! auxin polar transport + +[Term] +id: GO:0010542 +name: nitrate efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane." [GOC:mah] +is_a: GO:0015513 ! high-affinity secondary active nitrite transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity + +[Term] +id: GO:0010543 +name: regulation of platelet activation +namespace: biological_process +def: "Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030168 ! platelet activation +relationship: regulates GO:0030168 ! platelet activation + +[Term] +id: GO:0010544 +name: negative regulation of platelet activation +namespace: biological_process +def: "Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010543 ! regulation of platelet activation +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:0050866 ! negative regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030168 ! platelet activation +relationship: negatively_regulates GO:0030168 ! platelet activation + +[Term] +id: GO:0010545 +name: obsolete Hsp90 protein regulator activity +namespace: molecular_function +def: "OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90." [GOC:dph, GOC:tb, PMID:11146632] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'. +synonym: "Hsp90 protein regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051879 +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0010546 +name: obsolete Hsp90 protein inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone." [GOC:dph, GOC:tb, PMID:11146632] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'. +synonym: "Hsp90 protein inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051879 +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0010547 +name: thylakoid membrane disassembly +namespace: biological_process +def: "The controlled breakdown of the thylakoid membrane in the context of a normal process." [GOC:dph, GOC:tb, PMID:17416733] +synonym: "thylakoid membrane degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010027 ! thylakoid membrane organization +is_a: GO:0030397 ! membrane disassembly +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0010548 +name: regulation of thylakoid membrane disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly." [GOC:dph, GOC:tb, PMID:17416733] +synonym: "regulation of thylakoid membrane degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010549 ! regulation of membrane disassembly +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010547 ! thylakoid membrane disassembly +relationship: regulates GO:0010547 ! thylakoid membrane disassembly +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0010549 +name: regulation of membrane disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030397 ! membrane disassembly +relationship: regulates GO:0030397 ! membrane disassembly + +[Term] +id: GO:0010550 +name: regulation of PSII associated light-harvesting complex II catabolic process +namespace: biological_process +def: "Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II." [GOC:dph, GOC:tb] +synonym: "regulation of LHCII catabolism" EXACT [GOC:dph, GOC:tb, PMID:17416733] +synonym: "regulation of LHCII degradation" EXACT [PMID:17416733] +is_a: GO:1903362 ! regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010304 ! PSII associated light-harvesting complex II catabolic process +relationship: regulates GO:0010304 ! PSII associated light-harvesting complex II catabolic process + +[Term] +id: GO:0010555 +name: response to mannitol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus." [PMID:17999646] +synonym: "response to mannitol stimulus" EXACT [GOC:dos] +is_a: GO:0009743 ! response to carbohydrate + +[Term] +id: GO:0010556 +name: regulation of macromolecule biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009059 ! macromolecule biosynthetic process +relationship: regulates GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0010557 +name: positive regulation of macromolecule biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009059 ! macromolecule biosynthetic process +relationship: positively_regulates GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0010558 +name: negative regulation of macromolecule biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009059 ! macromolecule biosynthetic process +relationship: negatively_regulates GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0010559 +name: regulation of glycoprotein biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] +is_a: GO:1903018 ! regulation of glycoprotein metabolic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009101 ! glycoprotein biosynthetic process +relationship: regulates GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0010560 +name: positive regulation of glycoprotein biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009101 ! glycoprotein biosynthetic process +relationship: positively_regulates GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0010561 +name: negative regulation of glycoprotein biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process +relationship: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0010562 +name: positive regulation of phosphorus metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051174 ! regulation of phosphorus metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process +relationship: positively_regulates GO:0006793 ! phosphorus metabolic process + +[Term] +id: GO:0010563 +name: negative regulation of phosphorus metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051174 ! regulation of phosphorus metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process +relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process + +[Term] +id: GO:0010564 +name: regulation of cell cycle process +namespace: biological_process +def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022402 ! cell cycle process +relationship: regulates GO:0022402 ! cell cycle process + +[Term] +id: GO:0010565 +name: regulation of cellular ketone metabolic process +namespace: biological_process +def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042180 ! cellular ketone metabolic process +relationship: regulates GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0010566 +name: regulation of ketone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042181 ! ketone biosynthetic process +relationship: regulates GO:0042181 ! ketone biosynthetic process + +[Term] +id: GO:0010567 +name: regulation of ketone catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042182 ! ketone catabolic process +relationship: regulates GO:0042182 ! ketone catabolic process + +[Term] +id: GO:0010568 +name: regulation of budding cell apical bud growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding." [GOC:dph, GOC:jp, GOC:tb, PMID:17417630] +is_a: GO:0007116 ! regulation of cell budding +is_a: GO:0040008 ! regulation of growth +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007118 ! budding cell apical bud growth +relationship: regulates GO:0007118 ! budding cell apical bud growth + +[Term] +id: GO:0010569 +name: regulation of double-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000724 ! double-strand break repair via homologous recombination +relationship: regulates GO:0000724 ! double-strand break repair via homologous recombination + +[Term] +id: GO:0010570 +name: regulation of filamentous growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0040008 ! regulation of growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030447 ! filamentous growth +relationship: regulates GO:0030447 ! filamentous growth + +[Term] +id: GO:0010571 +name: positive regulation of nuclear cell cycle DNA replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." [GOC:mtg_cell_cycle] +synonym: "positive regulation of DNA replication during S phase" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of DNA replication involved in S phase" EXACT [] +synonym: "positive regulation of DNA replication involved in S-phase" EXACT [] +is_a: GO:0033262 ! regulation of nuclear cell cycle DNA replication +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033260 ! nuclear DNA replication +relationship: positively_regulates GO:0033260 ! nuclear DNA replication + +[Term] +id: GO:0010572 +name: positive regulation of platelet activation +namespace: biological_process +def: "Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0010543 ! regulation of platelet activation +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:0050867 ! positive regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030168 ! platelet activation +relationship: positively_regulates GO:0030168 ! platelet activation + +[Term] +id: GO:0010573 +name: vascular endothelial growth factor production +namespace: biological_process +def: "The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rl] +synonym: "VEGF production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0010574 +name: regulation of vascular endothelial growth factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor." [GOC:rl] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010573 ! vascular endothelial growth factor production +relationship: regulates GO:0010573 ! vascular endothelial growth factor production + +[Term] +id: GO:0010575 +name: positive regulation of vascular endothelial growth factor production +namespace: biological_process +def: "Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor." [GOC:BHF, GOC:rl] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0010574 ! regulation of vascular endothelial growth factor production +relationship: positively_regulates GO:0010573 ! vascular endothelial growth factor production + +[Term] +id: GO:0010578 +name: regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway." [GOC:dph, GOC:signaling, GOC:tb] +synonym: "regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway" EXACT [] +synonym: "regulation of adenylate cyclase activity involved in G-protein signaling pathway" EXACT [GOC:signaling] +synonym: "regulation of adenylate cyclase activity involved in G-protein signalling" EXACT [GOC:mah] +is_a: GO:0045761 ! regulation of adenylate cyclase activity +intersection_of: GO:0045761 ! regulation of adenylate cyclase activity +intersection_of: part_of GO:0007188 ! adenylate cyclase-modulating G protein-coupled receptor signaling pathway +relationship: part_of GO:0007188 ! adenylate cyclase-modulating G protein-coupled receptor signaling pathway + +[Term] +id: GO:0010581 +name: regulation of starch biosynthetic process +namespace: biological_process +def: "An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch." [GOC:tb] +is_a: GO:0010962 ! regulation of glucan biosynthetic process +is_a: GO:2000904 ! regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019252 ! starch biosynthetic process +relationship: regulates GO:0019252 ! starch biosynthetic process + +[Term] +id: GO:0010582 +name: floral meristem determinacy +namespace: biological_process +def: "The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate)." [PMID:18441215] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010022 ! meristem determinacy +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0010583 +name: response to cyclopentenone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid." [PMID:18334669] +is_a: GO:0014070 ! response to organic cyclic compound + +[Term] +id: GO:0010584 +name: pollen exine formation +namespace: biological_process +def: "The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine." [GOC:dhl] +is_a: GO:0010208 ! pollen wall assembly + +[Term] +id: GO:0010585 +name: glutamine secretion +namespace: biological_process +def: "The controlled release of glutamine by a cell." [PMID:15208395] +is_a: GO:0006868 ! glutamine transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0010586 +name: miRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression." [PMID:17993620] +subset: goslim_drosophila +synonym: "microRNA metabolic process" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0010587 +name: miRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression." [PMID:17993620] +synonym: "microRNA catabolic process" EXACT [] +is_a: GO:0010586 ! miRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0010588 +name: cotyledon vascular tissue pattern formation +namespace: biological_process +def: "Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants." [PMID:10559439] +is_a: GO:0010051 ! xylem and phloem pattern formation +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0048826 ! cotyledon morphogenesis + +[Term] +id: GO:0010589 +name: leaf proximal/distal pattern formation +namespace: biological_process +def: "The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis." [PMID:18398054] +is_a: GO:0009954 ! proximal/distal pattern formation + +[Term] +id: GO:0010590 +name: regulation of septum digestion after cytokinesis +namespace: biological_process +alt_id: GO:1902467 +alt_id: GO:2001041 +def: "Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:19959363, PMID:21246752, PMID:22786806] +synonym: "regulation of cell separation after cytokinesis" RELATED [] +synonym: "regulation of cell separation following cytokinesis" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of mitotic cytokinetic cell separation" EXACT [] +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000920 ! septum digestion after cytokinesis +relationship: regulates GO:0000920 ! septum digestion after cytokinesis + +[Term] +id: GO:0010591 +name: regulation of lamellipodium assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] +synonym: "regulation of lamellipodium biogenesis" RELATED [GOC:mah] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902743 ! regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030032 ! lamellipodium assembly +relationship: regulates GO:0030032 ! lamellipodium assembly + +[Term] +id: GO:0010592 +name: positive regulation of lamellipodium assembly +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] +synonym: "positive regulation of lamellipodium biogenesis" RELATED [GOC:mah] +is_a: GO:0010591 ! regulation of lamellipodium assembly +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902745 ! positive regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030032 ! lamellipodium assembly +relationship: positively_regulates GO:0030032 ! lamellipodium assembly + +[Term] +id: GO:0010593 +name: negative regulation of lamellipodium assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] +synonym: "negative regulation of lamellipodium biogenesis" RELATED [GOC:mah] +is_a: GO:0010591 ! regulation of lamellipodium assembly +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902744 ! negative regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030032 ! lamellipodium assembly +relationship: negatively_regulates GO:0030032 ! lamellipodium assembly + +[Term] +id: GO:0010594 +name: regulation of endothelial cell migration +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010632 ! regulation of epithelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043542 ! endothelial cell migration +relationship: regulates GO:0043542 ! endothelial cell migration + +[Term] +id: GO:0010595 +name: positive regulation of endothelial cell migration +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010594 ! regulation of endothelial cell migration +is_a: GO:0010634 ! positive regulation of epithelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043542 ! endothelial cell migration +relationship: positively_regulates GO:0043542 ! endothelial cell migration + +[Term] +id: GO:0010596 +name: negative regulation of endothelial cell migration +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010594 ! regulation of endothelial cell migration +is_a: GO:0010633 ! negative regulation of epithelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043542 ! endothelial cell migration +relationship: negatively_regulates GO:0043542 ! endothelial cell migration + +[Term] +id: GO:0010597 +name: green leaf volatile biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid." [PMID:17163881] +is_a: GO:0019372 ! lipoxygenase pathway + +[Term] +id: GO:0010598 +name: NAD(P)H dehydrogenase complex (plastoquinone) +namespace: cellular_component +def: "Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool." [PMID:15608332] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0010599 +name: production of lsiRNA involved in RNA interference +namespace: biological_process +def: "Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions." [PMID:18003861] +synonym: "RNA interference, production of lsiRNA" EXACT [GOC:mah] +is_a: GO:0070918 ! production of small RNA involved in gene silencing by RNA +relationship: part_of GO:0016246 ! RNA interference + +[Term] +id: GO:0010600 +name: regulation of auxin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth." [PMID:18287041] +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0090354 ! regulation of auxin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009851 ! auxin biosynthetic process +relationship: regulates GO:0009851 ! auxin biosynthetic process + +[Term] +id: GO:0010601 +name: positive regulation of auxin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth." [PMID:18287041] +is_a: GO:0010600 ! regulation of auxin biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0090355 ! positive regulation of auxin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009851 ! auxin biosynthetic process +relationship: positively_regulates GO:0009851 ! auxin biosynthetic process + +[Term] +id: GO:0010602 +name: regulation of 1-aminocyclopropane-1-carboxylate metabolic process +namespace: biological_process +def: "Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants." [PMID:18055613] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018871 ! 1-aminocyclopropane-1-carboxylate metabolic process +relationship: regulates GO:0018871 ! 1-aminocyclopropane-1-carboxylate metabolic process + +[Term] +id: GO:0010603 +name: regulation of cytoplasmic mRNA processing body assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body." [GOC:dph, GOC:krc, GOC:tb] +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033962 ! cytoplasmic mRNA processing body assembly +relationship: regulates GO:0033962 ! cytoplasmic mRNA processing body assembly + +[Term] +id: GO:0010604 +name: positive regulation of macromolecule metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043170 ! macromolecule metabolic process +relationship: positively_regulates GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0010605 +name: negative regulation of macromolecule metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043170 ! macromolecule metabolic process +relationship: negatively_regulates GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0010606 +name: positive regulation of cytoplasmic mRNA processing body assembly +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body." [GOC:dph, GOC:krc, GOC:tb] +is_a: GO:0010603 ! regulation of cytoplasmic mRNA processing body assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033962 ! cytoplasmic mRNA processing body assembly +relationship: positively_regulates GO:0033962 ! cytoplasmic mRNA processing body assembly + +[Term] +id: GO:0010607 +name: negative regulation of cytoplasmic mRNA processing body assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body." [GOC:dph, GOC:krc, GOC:tb] +is_a: GO:0010603 ! regulation of cytoplasmic mRNA processing body assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033962 ! cytoplasmic mRNA processing body assembly +relationship: negatively_regulates GO:0033962 ! cytoplasmic mRNA processing body assembly + +[Term] +id: GO:0010608 +name: posttranscriptional regulation of gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression + +[Term] +id: GO:0010609 +name: mRNA localization resulting in posttranscriptional regulation of gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell." [GOC:dph, GOC:tb] +synonym: "mRNA localisation resulting in posttranscriptional regulation of gene expression" EXACT [] +synonym: "posttranscriptional regulation of gene expression by mRNA localisation" EXACT [GOC:mah] +synonym: "posttranscriptional regulation of gene expression by mRNA localization" EXACT [] +is_a: GO:0008298 ! intracellular mRNA localization +is_a: GO:0010608 ! posttranscriptional regulation of gene expression + +[Term] +id: GO:0010610 +name: regulation of mRNA stability involved in response to stress +namespace: biological_process +def: "Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance." [GOC:dph, GOC:tb] +is_a: GO:0043488 ! regulation of mRNA stability +intersection_of: GO:0043488 ! regulation of mRNA stability +intersection_of: part_of GO:0006950 ! response to stress +relationship: part_of GO:0033554 ! cellular response to stress + +[Term] +id: GO:0010611 +name: regulation of cardiac muscle hypertrophy +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb] +is_a: GO:0014743 ! regulation of muscle hypertrophy +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003300 ! cardiac muscle hypertrophy +relationship: regulates GO:0003300 ! cardiac muscle hypertrophy + +[Term] +id: GO:0010612 +name: regulation of cardiac muscle adaptation +namespace: biological_process +def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb] +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014887 ! cardiac muscle adaptation +relationship: regulates GO:0014887 ! cardiac muscle adaptation + +[Term] +id: GO:0010613 +name: positive regulation of cardiac muscle hypertrophy +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy +is_a: GO:0014742 ! positive regulation of muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003300 ! cardiac muscle hypertrophy +relationship: positively_regulates GO:0003300 ! cardiac muscle hypertrophy + +[Term] +id: GO:0010614 +name: negative regulation of cardiac muscle hypertrophy +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy +is_a: GO:0014741 ! negative regulation of muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy +relationship: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy + +[Term] +id: GO:0010615 +name: positive regulation of cardiac muscle adaptation +namespace: biological_process +def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010612 ! regulation of cardiac muscle adaptation +is_a: GO:0014744 ! positive regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014887 ! cardiac muscle adaptation +relationship: positively_regulates GO:0014887 ! cardiac muscle adaptation + +[Term] +id: GO:0010616 +name: negative regulation of cardiac muscle adaptation +namespace: biological_process +def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010612 ! regulation of cardiac muscle adaptation +is_a: GO:0014745 ! negative regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014887 ! cardiac muscle adaptation +relationship: negatively_regulates GO:0014887 ! cardiac muscle adaptation + +[Term] +id: GO:0010617 +name: circadian regulation of calcium ion oscillation +namespace: biological_process +def: "Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours." [PMID:17982000] +synonym: "circadian regulation of [Ca2+]cyt oscillation" RELATED [] +synonym: "circadian regulation of Ca2+ oscillation" RELATED [] +synonym: "circadian regulation of cytosolic calcium ion homeostasis" EXACT [GOC:dph, GOC:tb] +synonym: "circadian regulation of cytosolic free calcium ion oscillation" RELATED [] +is_a: GO:0007623 ! circadian rhythm +is_a: GO:0051480 ! regulation of cytosolic calcium ion concentration + +[Term] +id: GO:0010618 +name: aerenchyma formation +namespace: biological_process +def: "The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts." [PMID:18055613, PO:0005702] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0010619 +name: adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:signaling, GOC:tb] +synonym: "activation of adenylate cyclase activity by glucose involved in G-protein signaling" RELATED [GOC:dph, GOC:tb] +synonym: "activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway" RELATED [GOC:signaling] +synonym: "activation of adenylate cyclase activity by glucose-triggered G-protein signalling pathway" RELATED [GOC:mah] +synonym: "adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +relationship: part_of GO:0010255 ! glucose mediated signaling pathway + +[Term] +id: GO:0010620 +name: negative regulation of transcription by transcription factor catabolism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:bf, GOC:dph, GOC:tb] +is_a: GO:0036369 ! transcription factor catabolic process +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0036369 ! transcription factor catabolic process +intersection_of: negatively_regulates GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0010621 +name: negative regulation of transcription by transcription factor localization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor." [GOC:dph, GOC:tb] +synonym: "negative regulation of transcription by transcription factor localisation" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated + +[Term] +id: GO:0010622 +name: specification of ovule identity +namespace: biological_process +def: "The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] +is_a: GO:0003002 ! regionalization +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0048482 ! plant ovule morphogenesis + +[Term] +id: GO:0010623 +name: programmed cell death involved in cell development +namespace: biological_process +def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +comment: This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure. +synonym: "developmental programmed cell death" BROAD [] +synonym: "programmed cell death involved in development" BROAD [] +is_a: GO:0012501 ! programmed cell death +is_a: GO:0048869 ! cellular developmental process +intersection_of: GO:0012501 ! programmed cell death +intersection_of: part_of GO:0048468 ! cell development +relationship: part_of GO:0048468 ! cell development + +[Term] +id: GO:0010624 +name: regulation of Schwann cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0060251 ! regulation of glial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014010 ! Schwann cell proliferation +relationship: regulates GO:0014010 ! Schwann cell proliferation + +[Term] +id: GO:0010625 +name: positive regulation of Schwann cell proliferation +namespace: biological_process +def: "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0010624 ! regulation of Schwann cell proliferation +is_a: GO:0060252 ! positive regulation of glial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014010 ! Schwann cell proliferation +relationship: positively_regulates GO:0014010 ! Schwann cell proliferation + +[Term] +id: GO:0010626 +name: negative regulation of Schwann cell proliferation +namespace: biological_process +def: "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0010624 ! regulation of Schwann cell proliferation +is_a: GO:0060253 ! negative regulation of glial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014010 ! Schwann cell proliferation +relationship: negatively_regulates GO:0014010 ! Schwann cell proliferation + +[Term] +id: GO:0010628 +name: positive regulation of gene expression +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010467 ! gene expression +relationship: positively_regulates GO:0010467 ! gene expression + +[Term] +id: GO:0010629 +name: negative regulation of gene expression +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] +comment: This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010467 ! gene expression +relationship: negatively_regulates GO:0010467 ! gene expression + +[Term] +id: GO:0010630 +name: regulation of transcription, start site selection +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template." [GOC:dph, GOC:tb] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process + +[Term] +id: GO:0010631 +name: epithelial cell migration +namespace: biological_process +def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0090132 ! epithelium migration + +[Term] +id: GO:0010632 +name: regulation of epithelial cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010631 ! epithelial cell migration +relationship: regulates GO:0010631 ! epithelial cell migration + +[Term] +id: GO:0010633 +name: negative regulation of epithelial cell migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010632 ! regulation of epithelial cell migration +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010631 ! epithelial cell migration +relationship: negatively_regulates GO:0010631 ! epithelial cell migration + +[Term] +id: GO:0010634 +name: positive regulation of epithelial cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010632 ! regulation of epithelial cell migration +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010631 ! epithelial cell migration +relationship: positively_regulates GO:0010631 ! epithelial cell migration + +[Term] +id: GO:0010635 +name: regulation of mitochondrial fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008053 ! mitochondrial fusion +relationship: regulates GO:0008053 ! mitochondrial fusion + +[Term] +id: GO:0010636 +name: positive regulation of mitochondrial fusion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] +is_a: GO:0010635 ! regulation of mitochondrial fusion +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008053 ! mitochondrial fusion +relationship: positively_regulates GO:0008053 ! mitochondrial fusion + +[Term] +id: GO:0010637 +name: negative regulation of mitochondrial fusion +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] +is_a: GO:0010635 ! regulation of mitochondrial fusion +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008053 ! mitochondrial fusion +relationship: negatively_regulates GO:0008053 ! mitochondrial fusion + +[Term] +id: GO:0010638 +name: positive regulation of organelle organization +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] +synonym: "positive regulation of organelle organisation" EXACT [GOC:mah] +synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006996 ! organelle organization +relationship: positively_regulates GO:0006996 ! organelle organization + +[Term] +id: GO:0010639 +name: negative regulation of organelle organization +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] +synonym: "negative regulation of organelle organisation" EXACT [GOC:mah] +synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006996 ! organelle organization +relationship: negatively_regulates GO:0006996 ! organelle organization + +[Term] +id: GO:0010640 +name: regulation of platelet-derived growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "regulation of platelet-derived growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway +relationship: regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway + +[Term] +id: GO:0010641 +name: positive regulation of platelet-derived growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "positive regulation of platelet-derived growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0010640 ! regulation of platelet-derived growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway +relationship: positively_regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway + +[Term] +id: GO:0010642 +name: negative regulation of platelet-derived growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "negative regulation of platelet-derived growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0010640 ! regulation of platelet-derived growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway +relationship: negatively_regulates GO:0048008 ! platelet-derived growth factor receptor signaling pathway + +[Term] +id: GO:0010643 +name: cell communication by chemical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0007154 ! cell communication + +[Term] +id: GO:0010644 +name: cell communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0007154 ! cell communication + +[Term] +id: GO:0010645 +name: regulation of cell communication by chemical coupling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010643 ! cell communication by chemical coupling +relationship: regulates GO:0010643 ! cell communication by chemical coupling + +[Term] +id: GO:0010646 +name: regulation of cell communication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007154 ! cell communication +relationship: regulates GO:0007154 ! cell communication + +[Term] +id: GO:0010647 +name: positive regulation of cell communication +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007154 ! cell communication +relationship: positively_regulates GO:0007154 ! cell communication + +[Term] +id: GO:0010648 +name: negative regulation of cell communication +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007154 ! cell communication +relationship: negatively_regulates GO:0007154 ! cell communication + +[Term] +id: GO:0010649 +name: regulation of cell communication by electrical coupling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010644 ! cell communication by electrical coupling +relationship: regulates GO:0010644 ! cell communication by electrical coupling + +[Term] +id: GO:0010650 +name: positive regulation of cell communication by electrical coupling +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0010649 ! regulation of cell communication by electrical coupling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010644 ! cell communication by electrical coupling +relationship: positively_regulates GO:0010644 ! cell communication by electrical coupling + +[Term] +id: GO:0010651 +name: negative regulation of cell communication by electrical coupling +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0010649 ! regulation of cell communication by electrical coupling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010644 ! cell communication by electrical coupling +relationship: negatively_regulates GO:0010644 ! cell communication by electrical coupling + +[Term] +id: GO:0010652 +name: positive regulation of cell communication by chemical coupling +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010645 ! regulation of cell communication by chemical coupling +is_a: GO:0010647 ! positive regulation of cell communication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010643 ! cell communication by chemical coupling +relationship: positively_regulates GO:0010643 ! cell communication by chemical coupling + +[Term] +id: GO:0010653 +name: negative regulation of cell communication by chemical coupling +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0010645 ! regulation of cell communication by chemical coupling +is_a: GO:0010648 ! negative regulation of cell communication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010643 ! cell communication by chemical coupling +relationship: negatively_regulates GO:0010643 ! cell communication by chemical coupling + +[Term] +id: GO:0010654 +name: apical cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote." [GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0009793 ! embryo development ending in seed dormancy + +[Term] +id: GO:0010656 +name: negative regulation of muscle cell apoptotic process +namespace: biological_process +def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "negative regulation of muscle cell apoptosis" NARROW [] +is_a: GO:0010660 ! regulation of muscle cell apoptotic process +is_a: GO:0043066 ! negative regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010657 ! muscle cell apoptotic process +relationship: negatively_regulates GO:0010657 ! muscle cell apoptotic process + +[Term] +id: GO:0010657 +name: muscle cell apoptotic process +namespace: biological_process +def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "muscle cell apoptosis" NARROW [] +is_a: GO:0006915 ! apoptotic process + +[Term] +id: GO:0010658 +name: striated muscle cell apoptotic process +namespace: biological_process +def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "striated muscle cell apoptosis" NARROW [] +is_a: GO:0010657 ! muscle cell apoptotic process + +[Term] +id: GO:0010659 +name: cardiac muscle cell apoptotic process +namespace: biological_process +def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "cardiac muscle cell apoptosis" NARROW [] +is_a: GO:0010658 ! striated muscle cell apoptotic process + +[Term] +id: GO:0010660 +name: regulation of muscle cell apoptotic process +namespace: biological_process +def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "regulation of muscle cell apoptosis" NARROW [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010657 ! muscle cell apoptotic process +relationship: regulates GO:0010657 ! muscle cell apoptotic process + +[Term] +id: GO:0010661 +name: positive regulation of muscle cell apoptotic process +namespace: biological_process +def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "positive regulation of muscle cell apoptosis" NARROW [] +is_a: GO:0010660 ! regulation of muscle cell apoptotic process +is_a: GO:0043065 ! positive regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010657 ! muscle cell apoptotic process +relationship: positively_regulates GO:0010657 ! muscle cell apoptotic process + +[Term] +id: GO:0010662 +name: regulation of striated muscle cell apoptotic process +namespace: biological_process +def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "regulation of striated muscle cell apoptosis" NARROW [] +is_a: GO:0010660 ! regulation of muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010658 ! striated muscle cell apoptotic process +relationship: regulates GO:0010658 ! striated muscle cell apoptotic process + +[Term] +id: GO:0010663 +name: positive regulation of striated muscle cell apoptotic process +namespace: biological_process +def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "positive regulation of striated muscle cell apoptosis" NARROW [] +is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process +is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010658 ! striated muscle cell apoptotic process +relationship: positively_regulates GO:0010658 ! striated muscle cell apoptotic process + +[Term] +id: GO:0010664 +name: negative regulation of striated muscle cell apoptotic process +namespace: biological_process +def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] +synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "inhibition of striated muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] +synonym: "negative regulation of striated muscle cell apoptosis" NARROW [] +is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process +is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process +relationship: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process + +[Term] +id: GO:0010665 +name: regulation of cardiac muscle cell apoptotic process +namespace: biological_process +def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "regulation of cardiac muscle cell apoptosis" NARROW [] +is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010659 ! cardiac muscle cell apoptotic process +relationship: regulates GO:0010659 ! cardiac muscle cell apoptotic process + +[Term] +id: GO:0010666 +name: positive regulation of cardiac muscle cell apoptotic process +namespace: biological_process +def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "positive regulation of cardiac muscle cell apoptosis" NARROW [] +is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process +is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process +relationship: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process + +[Term] +id: GO:0010667 +name: negative regulation of cardiac muscle cell apoptotic process +namespace: biological_process +def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] +synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "inhibition of cardiac muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] +synonym: "negative regulation of cardiac muscle cell apoptosis" NARROW [] +is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process +is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process +relationship: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process + +[Term] +id: GO:0010668 +name: ectodermal cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007398 ! ectoderm development + +[Term] +id: GO:0010669 +name: epithelial structure maintenance +namespace: biological_process +def: "A tissue homeostatic process required for the maintenance of epithelial structure." [GOC:dph, GOC:tb] +is_a: GO:0001894 ! tissue homeostasis + +[Term] +id: GO:0010670 +name: obsolete positive regulation of oxygen and reactive oxygen species metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH)." [GOC:BHF, GOC:dph, GOC:tb] +comment: This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together. +synonym: "positive regulation of oxygen and reactive oxygen species metabolic process" EXACT [] +is_obsolete: true +consider: GO:2000376 +consider: GO:2000379 + +[Term] +id: GO:0010671 +name: obsolete negative regulation of oxygen and reactive oxygen species metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH)." [GOC:BHF, GOC:dph, GOC:tb] +comment: This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together. +synonym: "negative regulation of oxygen and reactive oxygen species metabolic process" EXACT [] +is_obsolete: true +consider: GO:2000375 +consider: GO:2000378 + +[Term] +id: GO:0010672 +name: regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle +namespace: biological_process +alt_id: GO:1900401 +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." [GOC:dph, GOC:tb, PMID:12161753] +synonym: "regulation of meiosis by regulation of transcription from RNA polymerase II promoter" NARROW [] +synonym: "regulation of transcription from RNA polymerase II promoter, meiotic" EXACT [GOC:mah] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0051037 ! regulation of transcription involved in meiotic cell cycle +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: mah +creation_date: 2012-04-20T02:45:12Z + +[Term] +id: GO:0010673 +name: positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle +namespace: biological_process +alt_id: GO:1900476 +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." [GOC:dph, GOC:tb, PMID:8618927] +synonym: "activation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [] +synonym: "positive regulation of transcription from RNA polymerase II promoter, meiotic" EXACT [GOC:mah] +synonym: "stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +is_a: GO:0010672 ! regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0051039 ! positive regulation of transcription involved in meiotic cell cycle +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: dgf +creation_date: 2012-05-01T08:40:11Z + +[Term] +id: GO:0010674 +name: negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle +namespace: biological_process +alt_id: GO:1900475 +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." [GOC:dph, GOC:tb, PMID:8618927] +synonym: "activation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, meiotic" EXACT [GOC:mah] +synonym: "positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [] +synonym: "stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0010672 ! regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle +is_a: GO:0051038 ! negative regulation of transcription involved in meiotic cell cycle +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: dgf +creation_date: 2012-05-01T08:39:58Z + +[Term] +id: GO:0010675 +name: regulation of cellular carbohydrate metabolic process +namespace: biological_process +def: "Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044262 ! cellular carbohydrate metabolic process +relationship: regulates GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0010676 +name: positive regulation of cellular carbohydrate metabolic process +namespace: biological_process +def: "Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044262 ! cellular carbohydrate metabolic process +relationship: positively_regulates GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0010677 +name: negative regulation of cellular carbohydrate metabolic process +namespace: biological_process +def: "Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044262 ! cellular carbohydrate metabolic process +relationship: negatively_regulates GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0010678 +name: negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated +namespace: biological_process +def: "Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription." [GOC:dph, GOC:tb] +synonym: "negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent" EXACT [GOC:txnOH] +synonym: "negative regulation of cellular carbohydrate metabolic process by repression of transcription" EXACT [GOC:bf, GOC:vw] +synonym: "negative regulation of cellular carbohydrate metabolic process by transcriptional repression" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: negatively_regulates GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0010679 +name: cinnamic acid biosynthetic process involved in salicylic acid metabolism +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid." [GOC:dph, GOC:tb] +is_a: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: part_of GO:0009696 ! salicylic acid metabolic process +relationship: part_of GO:0009696 ! salicylic acid metabolic process + +[Term] +id: GO:0010680 +name: cinnamic acid biosynthetic process involved in coumarin metabolism +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin." [GOC:dph, GOC:tb] +is_a: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: part_of GO:0009804 ! coumarin metabolic process +relationship: part_of GO:0009804 ! coumarin metabolic process + +[Term] +id: GO:0010681 +name: cinnamic acid biosynthetic process involved in stilbene metabolism +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene." [GOC:dph, GOC:tb] +is_a: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: part_of GO:0009810 ! stilbene metabolic process +relationship: part_of GO:0009810 ! stilbene metabolic process + +[Term] +id: GO:0010682 +name: cinnamic acid biosynthetic process involved in flavonoid metabolism +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids." [GOC:dph, GOC:tb] +is_a: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: GO:0009800 ! cinnamic acid biosynthetic process +intersection_of: part_of GO:0009812 ! flavonoid metabolic process +relationship: part_of GO:0009812 ! flavonoid metabolic process + +[Term] +id: GO:0010683 +name: tricyclic triterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings." [GOC:tair_curators] +synonym: "tricyclic triterpenoid metabolism" EXACT [GOC:tair_curators] +is_a: GO:0006722 ! triterpenoid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0010684 +name: tricyclic triterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings." [GOC:tair_curators] +synonym: "tricyclic triterpenoid catabolism" EXACT [GOC:tair_curators] +is_a: GO:0010683 ! tricyclic triterpenoid metabolic process +is_a: GO:0016105 ! triterpenoid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0010685 +name: tetracyclic triterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings." [GOC:tair_curators] +synonym: "tetracyclic triterpenoid metabolism" EXACT [GOC:tair_curators] +is_a: GO:0006722 ! triterpenoid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0010686 +name: tetracyclic triterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings." [GOC:tair_curators] +synonym: "tetracyclic triterpenoid biosynthesis" EXACT [GOC:tair_curators] +is_a: GO:0010685 ! tetracyclic triterpenoid metabolic process +is_a: GO:0016104 ! triterpenoid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0010688 +name: negative regulation of ribosomal protein gene transcription by RNA polymerase II +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II." [GOC:dph, GOC:tb, GOC:txnOH] +synonym: "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0060962 ! regulation of ribosomal protein gene transcription by RNA polymerase II + +[Term] +id: GO:0010689 +name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0010688 ! negative regulation of ribosomal protein gene transcription by RNA polymerase II +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0010690 +name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0010688 ! negative regulation of ribosomal protein gene transcription by RNA polymerase II +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0010691 +name: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0010688 ! negative regulation of ribosomal protein gene transcription by RNA polymerase II +is_a: GO:0031669 ! cellular response to nutrient levels + +[Term] +id: GO:0010692 +name: regulation of alkaline phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:dph, GOC:tb] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004035 ! alkaline phosphatase activity +relationship: regulates GO:0004035 ! alkaline phosphatase activity + +[Term] +id: GO:0010693 +name: negative regulation of alkaline phosphatase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010692 ! regulation of alkaline phosphatase activity +is_a: GO:0010923 ! negative regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004035 ! alkaline phosphatase activity +relationship: negatively_regulates GO:0004035 ! alkaline phosphatase activity + +[Term] +id: GO:0010694 +name: positive regulation of alkaline phosphatase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:dph, GOC:tb] +is_a: GO:0010692 ! regulation of alkaline phosphatase activity +is_a: GO:0010922 ! positive regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004035 ! alkaline phosphatase activity +relationship: positively_regulates GO:0004035 ! alkaline phosphatase activity + +[Term] +id: GO:0010695 +name: regulation of mitotic spindle pole body separation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane." [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339] +synonym: "regulation of SPB separation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0110159 ! regulation of mitotic spindle formation (spindle phase one) +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000073 ! initial mitotic spindle pole body separation +relationship: regulates GO:0000073 ! initial mitotic spindle pole body separation + +[Term] +id: GO:0010696 +name: positive regulation of mitotic spindle pole body separation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane." [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339] +synonym: "positive regulation of SPB separation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010695 ! regulation of mitotic spindle pole body separation +is_a: GO:0110161 ! positive regulation of mitotic spindle formation (spindle phase one) +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000073 ! initial mitotic spindle pole body separation +relationship: positively_regulates GO:0000073 ! initial mitotic spindle pole body separation + +[Term] +id: GO:0010697 +name: negative regulation of mitotic spindle pole body separation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane." [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339] +synonym: "negative regulation of SPB separation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010695 ! regulation of mitotic spindle pole body separation +is_a: GO:0110160 ! negative regulation of mitotic spindle formation (spindle phase one) +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000073 ! initial mitotic spindle pole body separation +relationship: negatively_regulates GO:0000073 ! initial mitotic spindle pole body separation + +[Term] +id: GO:0010698 +name: acetyltransferase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule." [GOC:dph, GOC:jp, GOC:tb, PMID:18690240] +synonym: "acetyltransferase stimulator activity" EXACT [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0010700 +name: negative regulation of norepinephrine secretion +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0014061 ! regulation of norepinephrine secretion +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0033604 ! negative regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048243 ! norepinephrine secretion +relationship: negatively_regulates GO:0048243 ! norepinephrine secretion + +[Term] +id: GO:0010701 +name: positive regulation of norepinephrine secretion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0014061 ! regulation of norepinephrine secretion +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0033605 ! positive regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048243 ! norepinephrine secretion +relationship: positively_regulates GO:0048243 ! norepinephrine secretion + +[Term] +id: GO:0010702 +name: obsolete regulation of histolysis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants. +is_obsolete: true +consider: GO:0008219 +consider: GO:0012501 + +[Term] +id: GO:0010703 +name: obsolete negative regulation of histolysis +namespace: biological_process +def: "OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants. +synonym: "down regulation of histolysis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "down-regulation of histolysis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "downregulation of histolysis" EXACT [GOC:dph, GOC:rl, GOC:tb] +synonym: "inhibition of histolysis" NARROW [GOC:dph, GOC:rl, GOC:tb] +is_obsolete: true +consider: GO:0008219 +consider: GO:0012501 + +[Term] +id: GO:0010704 +name: meiotic DNA double-strand break processing involved in meiotic gene conversion +namespace: biological_process +def: "The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another." [GOC:dph, GOC:tb] +is_a: GO:0000706 ! meiotic DNA double-strand break processing +intersection_of: GO:0000706 ! meiotic DNA double-strand break processing +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010705 +name: meiotic DNA double-strand break processing involved in reciprocal meiotic recombination +namespace: biological_process +def: "The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000706 ! meiotic DNA double-strand break processing +intersection_of: GO:0000706 ! meiotic DNA double-strand break processing +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010706 +name: ganglioside biosynthetic process via lactosylceramide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group." [GOC:bf, GOC:dph, GOC:tb] +synonym: "biosynthesis of lactosylceramide precursor to ganglioside" RELATED [GOC:bf, GOC:dph, GOC:tb] +synonym: "ganglioside biosynthesis via lactosylceramide biosynthesis" EXACT [GOC:bf] +synonym: "lactosylceramide biosynthesis leading to ganglioside" RELATED [GOC:dph, GOC:tb] +synonym: "lactosylceramide biosynthetic process leading to ganglioside" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001574 ! ganglioside biosynthetic process + +[Term] +id: GO:0010707 +name: globoside biosynthetic process via lactosylceramide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group." [GOC:bf, GOC:dph, GOC:tb] +synonym: "biosynthesis of lactosylceramide precursor to globoside" RELATED [GOC:bf, GOC:dph, GOC:tb] +synonym: "globoside biosynthesis via lactosylceramide biosynthesis" EXACT [GOC:bf] +synonym: "lactosylceramide biosynthesis leading to globoside" RELATED [GOC:dph, GOC:tb] +synonym: "lactosylceramide biosynthetic process leading to globoside" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001576 ! globoside biosynthetic process + +[Term] +id: GO:0010708 +name: heteroduplex formation involved in gene conversion at mating-type locus +namespace: biological_process +def: "The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the conversion of the mating-type locus from one allele to another." [GOC:dph, GOC:tb] +is_a: GO:0022414 ! reproductive process +is_a: GO:0030491 ! heteroduplex formation +intersection_of: GO:0030491 ! heteroduplex formation +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0010709 +name: heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing +namespace: biological_process +def: "The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences." [GOC:dph, GOC:tb] +is_a: GO:0030491 ! heteroduplex formation +intersection_of: GO:0030491 ! heteroduplex formation +intersection_of: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing +relationship: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing + +[Term] +id: GO:0010710 +name: regulation of collagen catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009894 ! regulation of catabolic process +is_a: GO:0010712 ! regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030574 ! collagen catabolic process +relationship: regulates GO:0030574 ! collagen catabolic process + +[Term] +id: GO:0010711 +name: negative regulation of collagen catabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +synonym: "inhibition of collagen catabolic process" NARROW [GOC:dph, GOC:tb] +synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010710 ! regulation of collagen catabolic process +is_a: GO:0010713 ! negative regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030574 ! collagen catabolic process +relationship: negatively_regulates GO:0030574 ! collagen catabolic process + +[Term] +id: GO:0010712 +name: regulation of collagen metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] +synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032963 ! collagen metabolic process +relationship: regulates GO:0032963 ! collagen metabolic process + +[Term] +id: GO:0010713 +name: negative regulation of collagen metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0010712 ! regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032963 ! collagen metabolic process +relationship: negatively_regulates GO:0032963 ! collagen metabolic process + +[Term] +id: GO:0010714 +name: positive regulation of collagen metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] +synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0010712 ! regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032963 ! collagen metabolic process +relationship: positively_regulates GO:0032963 ! collagen metabolic process + +[Term] +id: GO:0010715 +name: regulation of extracellular matrix disassembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022617 ! extracellular matrix disassembly +relationship: regulates GO:0022617 ! extracellular matrix disassembly + +[Term] +id: GO:0010716 +name: negative regulation of extracellular matrix disassembly +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] +synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] +synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] +synonym: "inhibition of extracellular matrix disassembly" NARROW [GOC:dph, GOC:tb] +synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010715 ! regulation of extracellular matrix disassembly +is_a: GO:1903054 ! negative regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022617 ! extracellular matrix disassembly +relationship: negatively_regulates GO:0022617 ! extracellular matrix disassembly + +[Term] +id: GO:0010717 +name: regulation of epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001837 ! epithelial to mesenchymal transition +relationship: regulates GO:0001837 ! epithelial to mesenchymal transition + +[Term] +id: GO:0010718 +name: positive regulation of epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001837 ! epithelial to mesenchymal transition +relationship: positively_regulates GO:0001837 ! epithelial to mesenchymal transition + +[Term] +id: GO:0010719 +name: negative regulation of epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition +relationship: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition + +[Term] +id: GO:0010720 +name: positive regulation of cell development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048468 ! cell development +relationship: positively_regulates GO:0048468 ! cell development + +[Term] +id: GO:0010721 +name: negative regulation of cell development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048468 ! cell development +relationship: negatively_regulates GO:0048468 ! cell development + +[Term] +id: GO:0010722 +name: regulation of ferrochelatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+." [GOC:dph, GOC:tb] +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004325 ! ferrochelatase activity +relationship: regulates GO:0004325 ! ferrochelatase activity + +[Term] +id: GO:0010723 +name: positive regulation of transcription from RNA polymerase II promoter in response to iron +namespace: biological_process +def: "Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus." [GOC:dph, GOC:tb] +is_a: GO:0034395 ! regulation of transcription from RNA polymerase II promoter in response to iron +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus + +[Term] +id: GO:0010724 +name: regulation of definitive erythrocyte differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis." [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation of definitive erythropoiesis" EXACT [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation of definitive RBC differentiation" EXACT [CL:0000232] +synonym: "regulation of definitive red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0045646 ! regulation of erythrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060318 ! definitive erythrocyte differentiation +relationship: regulates GO:0060318 ! definitive erythrocyte differentiation + +[Term] +id: GO:0010725 +name: regulation of primitive erythrocyte differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis." [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation of primitive erythropoeisis" EXACT [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation of primitive RBC differentiation" EXACT [CL:0000232] +synonym: "regulation of primitive red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0045646 ! regulation of erythrocyte differentiation +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060319 ! primitive erythrocyte differentiation +relationship: regulates GO:0060319 ! primitive erythrocyte differentiation + +[Term] +id: GO:0010726 +name: positive regulation of hydrogen peroxide metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "positive regulation of hydrogen peroxide metabolism" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0010310 ! regulation of hydrogen peroxide metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042743 ! hydrogen peroxide metabolic process +relationship: positively_regulates GO:0042743 ! hydrogen peroxide metabolic process + +[Term] +id: GO:0010727 +name: negative regulation of hydrogen peroxide metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "negative regulation of hydrogen peroxide metabolism" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0010310 ! regulation of hydrogen peroxide metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042743 ! hydrogen peroxide metabolic process +relationship: negatively_regulates GO:0042743 ! hydrogen peroxide metabolic process + +[Term] +id: GO:0010728 +name: regulation of hydrogen peroxide biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "regulation of hydrogen peroxide biosynthesis" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0010310 ! regulation of hydrogen peroxide metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050665 ! hydrogen peroxide biosynthetic process +relationship: regulates GO:0050665 ! hydrogen peroxide biosynthetic process + +[Term] +id: GO:0010729 +name: positive regulation of hydrogen peroxide biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "positive regulation of hydrogen peroxide biosynthesis" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0010726 ! positive regulation of hydrogen peroxide metabolic process +is_a: GO:0010728 ! regulation of hydrogen peroxide biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1903428 ! positive regulation of reactive oxygen species biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050665 ! hydrogen peroxide biosynthetic process +relationship: positively_regulates GO:0050665 ! hydrogen peroxide biosynthetic process + +[Term] +id: GO:0010730 +name: negative regulation of hydrogen peroxide biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA." [GOC:dph, GOC:hjd, GOC:tb] +synonym: "negative regulation of hydrogen peroxide biosynthesis" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0010727 ! negative regulation of hydrogen peroxide metabolic process +is_a: GO:0010728 ! regulation of hydrogen peroxide biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1903427 ! negative regulation of reactive oxygen species biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050665 ! hydrogen peroxide biosynthetic process +relationship: negatively_regulates GO:0050665 ! hydrogen peroxide biosynthetic process + +[Term] +id: GO:0010731 +name: protein glutathionylation +namespace: biological_process +def: "The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +synonym: "protein amino acid glutathionylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0010732 +name: regulation of protein glutathionylation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +synonym: "regulation of protein amino acid glutathionylation" EXACT [GOC:bf] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010731 ! protein glutathionylation +relationship: regulates GO:0010731 ! protein glutathionylation + +[Term] +id: GO:0010733 +name: positive regulation of protein glutathionylation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +synonym: "positive regulation of protein amino acid glutathionylation" EXACT [GOC:bf] +is_a: GO:0010732 ! regulation of protein glutathionylation +is_a: GO:0031401 ! positive regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010731 ! protein glutathionylation +relationship: positively_regulates GO:0010731 ! protein glutathionylation + +[Term] +id: GO:0010734 +name: negative regulation of protein glutathionylation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +synonym: "negative regulation of protein amino acid glutathionylation" EXACT [GOC:bf] +is_a: GO:0010732 ! regulation of protein glutathionylation +is_a: GO:0031400 ! negative regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010731 ! protein glutathionylation +relationship: negatively_regulates GO:0010731 ! protein glutathionylation + +[Term] +id: GO:0010735 +name: positive regulation of transcription via serum response element binding +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II + +[Term] +id: GO:0010736 +name: serum response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding + +[Term] +id: GO:0010737 +name: protein kinase A signaling +namespace: biological_process +def: "A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "PKA signaling cascade" RELATED [GOC:dph, GOC:tb] +synonym: "protein kinase A signal transduction" EXACT [GOC:signaling] +synonym: "protein kinase A signaling cascade" RELATED [GOC:signaling] +synonym: "protein kinase A signalling cascade" RELATED [GOC:mah] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0010738 +name: regulation of protein kinase A signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of PKA signaling cascade" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of protein kinase A signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of protein kinase A signalling cascade" RELATED [GOC:mah] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010737 ! protein kinase A signaling +relationship: regulates GO:0010737 ! protein kinase A signaling + +[Term] +id: GO:0010739 +name: positive regulation of protein kinase A signaling +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of PKA signaling cascade" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of protein kinase A signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of protein kinase A signalling cascade" RELATED [GOC:mah] +is_a: GO:0010738 ! regulation of protein kinase A signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010737 ! protein kinase A signaling +relationship: positively_regulates GO:0010737 ! protein kinase A signaling + +[Term] +id: GO:0010742 +name: macrophage derived foam cell differentiation +namespace: biological_process +def: "The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:dph, GOC:tb] +is_a: GO:0090077 ! foam cell differentiation + +[Term] +id: GO:0010743 +name: regulation of macrophage derived foam cell differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010742 ! macrophage derived foam cell differentiation +relationship: regulates GO:0010742 ! macrophage derived foam cell differentiation + +[Term] +id: GO:0010744 +name: positive regulation of macrophage derived foam cell differentiation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:dph, GOC:tb] +is_a: GO:0010743 ! regulation of macrophage derived foam cell differentiation +is_a: GO:0045597 ! positive regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010742 ! macrophage derived foam cell differentiation +relationship: positively_regulates GO:0010742 ! macrophage derived foam cell differentiation + +[Term] +id: GO:0010745 +name: negative regulation of macrophage derived foam cell differentiation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010743 ! regulation of macrophage derived foam cell differentiation +is_a: GO:0045596 ! negative regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010742 ! macrophage derived foam cell differentiation +relationship: negatively_regulates GO:0010742 ! macrophage derived foam cell differentiation + +[Term] +id: GO:0010746 +name: regulation of long-chain fatty acid import across plasma membrane +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of plasma membrane long-chain fatty acid transport" EXACT [] +is_a: GO:0140212 ! regulation of long-chain fatty acid import into cell +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015911 ! long-chain fatty acid import across plasma membrane +relationship: regulates GO:0015911 ! long-chain fatty acid import across plasma membrane + +[Term] +id: GO:0010747 +name: positive regulation of long-chain fatty acid import across plasma membrane +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of plasma membrane long-chain fatty acid transport" EXACT [] +is_a: GO:0010746 ! regulation of long-chain fatty acid import across plasma membrane +is_a: GO:0140214 ! positive regulation of long-chain fatty acid import into cell +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015911 ! long-chain fatty acid import across plasma membrane +relationship: positively_regulates GO:0015911 ! long-chain fatty acid import across plasma membrane + +[Term] +id: GO:0010748 +name: negative regulation of long-chain fatty acid import across plasma membrane +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of plasma membrane long-chain fatty acid transport" EXACT [] +is_a: GO:0010746 ! regulation of long-chain fatty acid import across plasma membrane +is_a: GO:0140213 ! negative regulation of long-chain fatty acid import into cell +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015911 ! long-chain fatty acid import across plasma membrane +relationship: negatively_regulates GO:0015911 ! long-chain fatty acid import across plasma membrane + +[Term] +id: GO:0010749 +name: regulation of nitric oxide mediated signal transduction +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO)." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of nitric oxide-mediated signal transduction" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007263 ! nitric oxide mediated signal transduction +relationship: regulates GO:0007263 ! nitric oxide mediated signal transduction + +[Term] +id: GO:0010750 +name: positive regulation of nitric oxide mediated signal transduction +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO)." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of nitric oxide-mediated signal transduction" EXACT [] +is_a: GO:0010749 ! regulation of nitric oxide mediated signal transduction +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007263 ! nitric oxide mediated signal transduction +relationship: positively_regulates GO:0007263 ! nitric oxide mediated signal transduction + +[Term] +id: GO:0010751 +name: negative regulation of nitric oxide mediated signal transduction +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO)." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of nitric oxide-mediated signal transduction" EXACT [] +is_a: GO:0010749 ! regulation of nitric oxide mediated signal transduction +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007263 ! nitric oxide mediated signal transduction +relationship: negatively_regulates GO:0007263 ! nitric oxide mediated signal transduction + +[Term] +id: GO:0010752 +name: regulation of cGMP-mediated signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of cGMP-mediated signalling" EXACT [GOC:mah] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019934 ! cGMP-mediated signaling +relationship: regulates GO:0019934 ! cGMP-mediated signaling + +[Term] +id: GO:0010753 +name: positive regulation of cGMP-mediated signaling +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of cGMP-mediated signalling" EXACT [GOC:mah] +is_a: GO:0010752 ! regulation of cGMP-mediated signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019934 ! cGMP-mediated signaling +relationship: positively_regulates GO:0019934 ! cGMP-mediated signaling + +[Term] +id: GO:0010754 +name: negative regulation of cGMP-mediated signaling +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of cGMP-mediated signalling" EXACT [GOC:mah] +is_a: GO:0010752 ! regulation of cGMP-mediated signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019934 ! cGMP-mediated signaling +relationship: negatively_regulates GO:0019934 ! cGMP-mediated signaling + +[Term] +id: GO:0010755 +name: regulation of plasminogen activation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0070613 ! regulation of protein processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031639 ! plasminogen activation +relationship: regulates GO:0031639 ! plasminogen activation + +[Term] +id: GO:0010756 +name: positive regulation of plasminogen activation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010755 ! regulation of plasminogen activation +is_a: GO:0010954 ! positive regulation of protein processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031639 ! plasminogen activation +relationship: positively_regulates GO:0031639 ! plasminogen activation + +[Term] +id: GO:0010757 +name: negative regulation of plasminogen activation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "inhibition of plasminogen activation" NARROW [GOC:dph, GOC:tb] +is_a: GO:0010755 ! regulation of plasminogen activation +is_a: GO:0010955 ! negative regulation of protein processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031639 ! plasminogen activation +relationship: negatively_regulates GO:0031639 ! plasminogen activation + +[Term] +id: GO:0010758 +name: regulation of macrophage chemotaxis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +is_a: GO:1905521 ! regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048246 ! macrophage chemotaxis +relationship: regulates GO:0048246 ! macrophage chemotaxis + +[Term] +id: GO:0010759 +name: positive regulation of macrophage chemotaxis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:0010758 ! regulation of macrophage chemotaxis +is_a: GO:0071622 ! regulation of granulocyte chemotaxis +is_a: GO:0071675 ! regulation of mononuclear cell migration +is_a: GO:1905523 ! positive regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048246 ! macrophage chemotaxis +relationship: positively_regulates GO:0048246 ! macrophage chemotaxis + +[Term] +id: GO:0010760 +name: negative regulation of macrophage chemotaxis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:0010758 ! regulation of macrophage chemotaxis +is_a: GO:1905522 ! negative regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048246 ! macrophage chemotaxis +relationship: negatively_regulates GO:0048246 ! macrophage chemotaxis + +[Term] +id: GO:0010761 +name: fibroblast migration +namespace: biological_process +def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "fibroblast cell migration" EXACT [GOC:dph] +is_a: GO:0001667 ! ameboidal-type cell migration + +[Term] +id: GO:0010762 +name: regulation of fibroblast migration +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] +synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010761 ! fibroblast migration +relationship: regulates GO:0010761 ! fibroblast migration + +[Term] +id: GO:0010763 +name: positive regulation of fibroblast migration +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph] +is_a: GO:0010762 ! regulation of fibroblast migration +is_a: GO:0030335 ! positive regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010761 ! fibroblast migration +relationship: positively_regulates GO:0010761 ! fibroblast migration + +[Term] +id: GO:0010764 +name: negative regulation of fibroblast migration +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] +synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph] +is_a: GO:0010762 ! regulation of fibroblast migration +is_a: GO:0030336 ! negative regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010761 ! fibroblast migration +relationship: negatively_regulates GO:0010761 ! fibroblast migration + +[Term] +id: GO:0010765 +name: positive regulation of sodium ion transport +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0002028 ! regulation of sodium ion transport +is_a: GO:0043270 ! positive regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006814 ! sodium ion transport +relationship: positively_regulates GO:0006814 ! sodium ion transport + +[Term] +id: GO:0010766 +name: negative regulation of sodium ion transport +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0002028 ! regulation of sodium ion transport +is_a: GO:0043271 ! negative regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006814 ! sodium ion transport +relationship: negatively_regulates GO:0006814 ! sodium ion transport + +[Term] +id: GO:0010767 +name: regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus." [GOC:dph, GOC:tb] +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0034644 ! cellular response to UV +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress + +[Term] +id: GO:0010768 +name: negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus." [GOC:dph, GOC:tb] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0010767 ! regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage + +[Term] +id: GO:0010769 +name: regulation of cell morphogenesis involved in differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000904 ! cell morphogenesis involved in differentiation +relationship: regulates GO:0000904 ! cell morphogenesis involved in differentiation + +[Term] +id: GO:0010770 +name: positive regulation of cell morphogenesis involved in differentiation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000904 ! cell morphogenesis involved in differentiation +relationship: positively_regulates GO:0000904 ! cell morphogenesis involved in differentiation + +[Term] +id: GO:0010771 +name: negative regulation of cell morphogenesis involved in differentiation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000904 ! cell morphogenesis involved in differentiation +relationship: negatively_regulates GO:0000904 ! cell morphogenesis involved in differentiation + +[Term] +id: GO:0010772 +name: meiotic DNA recombinase assembly involved in reciprocal meiotic recombination +namespace: biological_process +def: "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000707 ! meiotic DNA recombinase assembly +intersection_of: GO:0000707 ! meiotic DNA recombinase assembly +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010773 +name: meiotic DNA recombinase assembly involved in meiotic gene conversion +namespace: biological_process +def: "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another." [GOC:dph, GOC:tb] +is_a: GO:0000707 ! meiotic DNA recombinase assembly +intersection_of: GO:0000707 ! meiotic DNA recombinase assembly +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010774 +name: meiotic strand invasion involved in reciprocal meiotic recombination +namespace: biological_process +def: "The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000708 ! meiotic strand invasion +intersection_of: GO:0000708 ! meiotic strand invasion +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010775 +name: meiotic strand invasion involved in meiotic gene conversion +namespace: biological_process +def: "The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination." [GOC:dph, GOC:tb] +is_a: GO:0000708 ! meiotic strand invasion +intersection_of: GO:0000708 ! meiotic strand invasion +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010776 +name: meiotic mismatch repair involved in meiotic gene conversion +namespace: biological_process +def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another." [GOC:dph, GOC:tb] +is_a: GO:0000710 ! meiotic mismatch repair +intersection_of: GO:0000710 ! meiotic mismatch repair +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010777 +name: meiotic mismatch repair involved in reciprocal meiotic recombination +namespace: biological_process +def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000710 ! meiotic mismatch repair +intersection_of: GO:0000710 ! meiotic mismatch repair +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010778 +name: meiotic DNA repair synthesis involved in reciprocal meiotic recombination +namespace: biological_process +def: "The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0000711 ! meiotic DNA repair synthesis +intersection_of: GO:0000711 ! meiotic DNA repair synthesis +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010779 +name: meiotic DNA repair synthesis involved in meiotic gene conversion +namespace: biological_process +def: "The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another." [GOC:dph, GOC:tb] +is_a: GO:0000711 ! meiotic DNA repair synthesis +intersection_of: GO:0000711 ! meiotic DNA repair synthesis +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010780 +name: meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +namespace: biological_process +def: "The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +is_a: GO:0042138 ! meiotic DNA double-strand break formation +intersection_of: GO:0042138 ! meiotic DNA double-strand break formation +intersection_of: part_of GO:0007131 ! reciprocal meiotic recombination +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010781 +name: meiotic DNA double-strand break formation involved in meiotic gene conversion +namespace: biological_process +def: "The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another." [GOC:dph, GOC:tb] +is_a: GO:0042138 ! meiotic DNA double-strand break formation +intersection_of: GO:0042138 ! meiotic DNA double-strand break formation +intersection_of: part_of GO:0006311 ! meiotic gene conversion +relationship: part_of GO:0006311 ! meiotic gene conversion + +[Term] +id: GO:0010782 +name: proboscis morphogenesis, labial disc-derived +namespace: biological_process +def: "The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized." [GOC:dph, GOC:tb] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007454 ! labial disc morphogenesis +relationship: part_of GO:0048734 ! proboscis morphogenesis + +[Term] +id: GO:0010783 +name: proboscis morphogenesis, eye-antennal disc-derived +namespace: biological_process +def: "The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized." [GOC:dph, GOC:tb] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007455 ! eye-antennal disc morphogenesis +relationship: part_of GO:0048734 ! proboscis morphogenesis + +[Term] +id: GO:0010784 +name: proboscis morphogenesis, clypeo-labral disc-derived +namespace: biological_process +def: "The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized." [GOC:dph, GOC:tb] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048734 ! proboscis morphogenesis + +[Term] +id: GO:0010785 +name: clathrin coating of Golgi vesicle, plasma membrane to endosome targeting +namespace: biological_process +def: "The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat." [GOC:dph, GOC:tb] +is_a: GO:0048202 ! clathrin coating of Golgi vesicle +relationship: part_of GO:0048201 ! vesicle targeting, plasma membrane to endosome + +[Term] +id: GO:0010786 +name: clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting +namespace: biological_process +def: "The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat." [GOC:dph, GOC:tb] +is_a: GO:0048202 ! clathrin coating of Golgi vesicle +relationship: part_of GO:0048203 ! vesicle targeting, trans-Golgi to endosome + +[Term] +id: GO:0010787 +name: COPI coating of Golgi vesicle, inter-Golgi cisterna +namespace: biological_process +def: "The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat." [GOC:dph, GOC:tb] +is_a: GO:0048205 ! COPI coating of Golgi vesicle +relationship: part_of GO:0048204 ! vesicle targeting, inter-Golgi cisterna + +[Term] +id: GO:0010788 +name: COPI coating of Golgi vesicle, cis-Golgi to rough ER +namespace: biological_process +def: "The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat." [GOC:dph, GOC:tb] +is_a: GO:0048205 ! COPI coating of Golgi vesicle +relationship: part_of GO:0048206 ! vesicle targeting, cis-Golgi to rough endoplasmic reticulum + +[Term] +id: GO:0010789 +name: meiotic sister chromatid cohesion involved in meiosis I +namespace: biological_process +def: "The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I." [GOC:dph, GOC:tb] +is_a: GO:0051177 ! meiotic sister chromatid cohesion +intersection_of: GO:0051177 ! meiotic sister chromatid cohesion +intersection_of: part_of GO:0007127 ! meiosis I +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0010790 +name: meiotic sister chromatid cohesion involved in meiosis II +namespace: biological_process +def: "The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II." [GOC:dph, GOC:tb] +is_a: GO:0051177 ! meiotic sister chromatid cohesion + +[Term] +id: GO:0010791 +name: DNA double-strand break processing involved in repair via synthesis-dependent strand annealing +namespace: biological_process +def: "The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing." [GOC:dph, GOC:tb] +is_a: GO:0000729 ! DNA double-strand break processing +intersection_of: GO:0000729 ! DNA double-strand break processing +intersection_of: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing +relationship: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing + +[Term] +id: GO:0010792 +name: DNA double-strand break processing involved in repair via single-strand annealing +namespace: biological_process +def: "The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing." [GOC:dph, GOC:tb] +is_a: GO:0000729 ! DNA double-strand break processing +intersection_of: GO:0000729 ! DNA double-strand break processing +intersection_of: part_of GO:0045002 ! double-strand break repair via single-strand annealing +relationship: part_of GO:0045002 ! double-strand break repair via single-strand annealing + +[Term] +id: GO:0010793 +name: regulation of mRNA export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm." [GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0046825 ! regulation of protein export from nucleus +is_a: GO:0046831 ! regulation of RNA export from nucleus +is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006406 ! mRNA export from nucleus +relationship: regulates GO:0006406 ! mRNA export from nucleus + +[Term] +id: GO:0010794 +name: regulation of dolichol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units." [GOC:dph, GOC:tb] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019408 ! dolichol biosynthetic process +relationship: regulates GO:0019408 ! dolichol biosynthetic process + +[Term] +id: GO:0010795 +name: regulation of ubiquinone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme." [GOC:dph, GOC:tb] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006744 ! ubiquinone biosynthetic process +relationship: regulates GO:0006744 ! ubiquinone biosynthetic process + +[Term] +id: GO:0010796 +name: regulation of multivesicular body size +namespace: biological_process +def: "Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0051036 ! regulation of endosome size + +[Term] +id: GO:0010797 +name: regulation of multivesicular body size involved in endosome transport +namespace: biological_process +def: "Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles." [GOC:dph, GOC:tb] +is_a: GO:0010796 ! regulation of multivesicular body size +intersection_of: GO:0010796 ! regulation of multivesicular body size +intersection_of: part_of GO:0016197 ! endosomal transport +relationship: part_of GO:0032509 ! endosome transport via multivesicular body sorting pathway + +[Term] +id: GO:0010798 +name: regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism +namespace: biological_process +def: "Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin." [GOC:dph, GOC:tb] +is_a: GO:0010796 ! regulation of multivesicular body size +intersection_of: GO:0010796 ! regulation of multivesicular body size +intersection_of: part_of GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: part_of GO:0006511 ! ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0010799 +name: regulation of peptidyl-threonine phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] +is_a: GO:0001932 ! regulation of protein phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018107 ! peptidyl-threonine phosphorylation +relationship: regulates GO:0018107 ! peptidyl-threonine phosphorylation + +[Term] +id: GO:0010800 +name: positive regulation of peptidyl-threonine phosphorylation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0010799 ! regulation of peptidyl-threonine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018107 ! peptidyl-threonine phosphorylation +relationship: positively_regulates GO:0018107 ! peptidyl-threonine phosphorylation + +[Term] +id: GO:0010801 +name: negative regulation of peptidyl-threonine phosphorylation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0010799 ! regulation of peptidyl-threonine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018107 ! peptidyl-threonine phosphorylation +relationship: negatively_regulates GO:0018107 ! peptidyl-threonine phosphorylation + +[Term] +id: GO:0010803 +name: regulation of tumor necrosis factor-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor." [GOC:dph, GOC:tb] +synonym: "regulation of TNF signaling" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of TNF-mediated signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway +relationship: regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway + +[Term] +id: GO:0010804 +name: negative regulation of tumor necrosis factor-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor." [GOC:dph, GOC:tb] +synonym: "negative regulation of TNF signaling" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of TNF-mediated signaling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0010803 ! regulation of tumor necrosis factor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway +relationship: negatively_regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway + +[Term] +id: GO:0010807 +name: regulation of synaptic vesicle priming +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion." [GOC:dph, GOC:kmv, GOC:tb, PMID:15489511] +subset: goslim_synapse +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016082 ! synaptic vesicle priming +relationship: regulates GO:0016082 ! synaptic vesicle priming + +[Term] +id: GO:0010808 +name: positive regulation of synaptic vesicle priming +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion." [GOC:dph, GOC:kmv, GOC:tb, PMID:15489511] +is_a: GO:0010807 ! regulation of synaptic vesicle priming +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:2000302 ! positive regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016082 ! synaptic vesicle priming +relationship: positively_regulates GO:0016082 ! synaptic vesicle priming + +[Term] +id: GO:0010809 +name: negative regulation of synaptic vesicle priming +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion." [GOC:dph, GOC:kmvs, GOC:tb, PMID:15489511] +is_a: GO:0010807 ! regulation of synaptic vesicle priming +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:2000301 ! negative regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016082 ! synaptic vesicle priming +relationship: negatively_regulates GO:0016082 ! synaptic vesicle priming + +[Term] +id: GO:0010810 +name: regulation of cell-substrate adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules." [GOC:dph, GOC:pf, GOC:tb] +is_a: GO:0030155 ! regulation of cell adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0031589 ! cell-substrate adhesion +relationship: regulates GO:0031589 ! cell-substrate adhesion + +[Term] +id: GO:0010811 +name: positive regulation of cell-substrate adhesion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules." [GOC:dph, GOC:pf, GOC:tb] +is_a: GO:0010810 ! regulation of cell-substrate adhesion +is_a: GO:0045785 ! positive regulation of cell adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0031589 ! cell-substrate adhesion +relationship: positively_regulates GO:0031589 ! cell-substrate adhesion + +[Term] +id: GO:0010812 +name: negative regulation of cell-substrate adhesion +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules." [GOC:dph, GOC:pf, GOC:tb] +is_a: GO:0007162 ! negative regulation of cell adhesion +is_a: GO:0010810 ! regulation of cell-substrate adhesion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0031589 ! cell-substrate adhesion +relationship: negatively_regulates GO:0031589 ! cell-substrate adhesion + +[Term] +id: GO:0010813 +name: neuropeptide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0043171 ! peptide catabolic process + +[Term] +id: GO:0010814 +name: substance P catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P." [GOC:BHF, GOC:rl] +is_a: GO:0010813 ! neuropeptide catabolic process + +[Term] +id: GO:0010815 +name: bradykinin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin." [GOC:BHF, GOC:rl] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043171 ! peptide catabolic process + +[Term] +id: GO:0010816 +name: calcitonin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin." [GOC:BHF, GOC:rl] +is_a: GO:0034754 ! cellular hormone metabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043171 ! peptide catabolic process + +[Term] +id: GO:0010817 +name: regulation of hormone levels +namespace: biological_process +def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0010818 +name: T cell chemotaxis +namespace: biological_process +def: "The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:dph, GOC:tb] +synonym: "T-cell chemotaxis" EXACT [CL:0000084] +is_a: GO:0048247 ! lymphocyte chemotaxis +is_a: GO:0072678 ! T cell migration + +[Term] +id: GO:0010819 +name: regulation of T cell chemotaxis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." [GOC:dph, GOC:tb] +is_a: GO:1901623 ! regulation of lymphocyte chemotaxis +is_a: GO:2000404 ! regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010818 ! T cell chemotaxis +relationship: regulates GO:0010818 ! T cell chemotaxis + +[Term] +id: GO:0010820 +name: positive regulation of T cell chemotaxis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010819 ! regulation of T cell chemotaxis +is_a: GO:0140131 ! positive regulation of lymphocyte chemotaxis +is_a: GO:2000406 ! positive regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010818 ! T cell chemotaxis +relationship: positively_regulates GO:0010818 ! T cell chemotaxis + +[Term] +id: GO:0010821 +name: regulation of mitochondrion organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." [GOC:dph, GOC:tb] +synonym: "regulation of mitochondrion organisation" EXACT [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007005 ! mitochondrion organization +relationship: regulates GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0010822 +name: positive regulation of mitochondrion organization +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." [GOC:dph, GOC:tb] +synonym: "positive regulation of mitochondrion organisation" EXACT [GOC:mah] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0010821 ! regulation of mitochondrion organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007005 ! mitochondrion organization +relationship: positively_regulates GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0010823 +name: negative regulation of mitochondrion organization +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." [GOC:dph, GOC:tb] +synonym: "negative regulation of mitochondrion organisation" EXACT [GOC:mah] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0010821 ! regulation of mitochondrion organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007005 ! mitochondrion organization +relationship: negatively_regulates GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0010824 +name: regulation of centrosome duplication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:dph, GOC:tb] +is_a: GO:0046605 ! regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051298 ! centrosome duplication +relationship: regulates GO:0051298 ! centrosome duplication + +[Term] +id: GO:0010825 +name: positive regulation of centrosome duplication +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:dph, GOC:tb] +is_a: GO:0010824 ! regulation of centrosome duplication +is_a: GO:0046607 ! positive regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051298 ! centrosome duplication +relationship: positively_regulates GO:0051298 ! centrosome duplication + +[Term] +id: GO:0010826 +name: negative regulation of centrosome duplication +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:dph, GOC:tb] +is_a: GO:0010824 ! regulation of centrosome duplication +is_a: GO:0046606 ! negative regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051298 ! centrosome duplication +relationship: negatively_regulates GO:0051298 ! centrosome duplication + +[Term] +id: GO:0010827 +name: regulation of glucose transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +synonym: "regulation of glucose transport" RELATED [] +is_a: GO:0034762 ! regulation of transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904659 ! glucose transmembrane transport +relationship: regulates GO:1904659 ! glucose transmembrane transport + +[Term] +id: GO:0010828 +name: positive regulation of glucose transmembrane transport +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of glucose transport" RELATED [] +is_a: GO:0010827 ! regulation of glucose transmembrane transport +is_a: GO:0034764 ! positive regulation of transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904659 ! glucose transmembrane transport +relationship: positively_regulates GO:1904659 ! glucose transmembrane transport + +[Term] +id: GO:0010829 +name: negative regulation of glucose transmembrane transport +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of glucose transport" RELATED [] +is_a: GO:0010827 ! regulation of glucose transmembrane transport +is_a: GO:0034763 ! negative regulation of transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904659 ! glucose transmembrane transport +relationship: negatively_regulates GO:1904659 ! glucose transmembrane transport + +[Term] +id: GO:0010830 +name: regulation of myotube differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] +is_a: GO:0051153 ! regulation of striated muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014902 ! myotube differentiation +relationship: regulates GO:0014902 ! myotube differentiation + +[Term] +id: GO:0010831 +name: positive regulation of myotube differentiation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] +is_a: GO:0010830 ! regulation of myotube differentiation +is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014902 ! myotube differentiation +relationship: positively_regulates GO:0014902 ! myotube differentiation + +[Term] +id: GO:0010832 +name: negative regulation of myotube differentiation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] +is_a: GO:0010830 ! regulation of myotube differentiation +is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014902 ! myotube differentiation +relationship: negatively_regulates GO:0014902 ! myotube differentiation + +[Term] +id: GO:0010833 +name: telomere maintenance via telomere lengthening +namespace: biological_process +def: "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA." [GOC:dph, GOC:tb] +is_a: GO:0000723 ! telomere maintenance + +[Term] +id: GO:0010834 +name: obsolete telomere maintenance via telomere shortening +namespace: biological_process +def: "OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it represents a phenotype. +synonym: "telomere maintenance via telomere shortening" EXACT [] +is_obsolete: true +consider: GO:1903824 + +[Term] +id: GO:0010835 +name: regulation of protein ADP-ribosylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids." [GOC:dph, GOC:tb] +synonym: "regulation of protein amino acid ADP-ribosylation" EXACT [GOC:bf] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006471 ! protein ADP-ribosylation +relationship: regulates GO:0006471 ! protein ADP-ribosylation + +[Term] +id: GO:0010836 +name: negative regulation of protein ADP-ribosylation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of protein amino acid ADP-ribosylation" EXACT [GOC:bf] +is_a: GO:0010835 ! regulation of protein ADP-ribosylation +is_a: GO:0031400 ! negative regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006471 ! protein ADP-ribosylation +relationship: negatively_regulates GO:0006471 ! protein ADP-ribosylation + +[Term] +id: GO:0010837 +name: regulation of keratinocyte proliferation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population." [GOC:dph, GOC:tb] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043616 ! keratinocyte proliferation +relationship: regulates GO:0043616 ! keratinocyte proliferation + +[Term] +id: GO:0010838 +name: positive regulation of keratinocyte proliferation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population." [GOC:dph, GOC:tb] +is_a: GO:0010837 ! regulation of keratinocyte proliferation +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043616 ! keratinocyte proliferation +relationship: positively_regulates GO:0043616 ! keratinocyte proliferation + +[Term] +id: GO:0010839 +name: negative regulation of keratinocyte proliferation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population." [GOC:dph, GOC:tb] +is_a: GO:0010837 ! regulation of keratinocyte proliferation +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043616 ! keratinocyte proliferation +relationship: negatively_regulates GO:0043616 ! keratinocyte proliferation + +[Term] +id: GO:0010840 +name: regulation of circadian sleep/wake cycle, wakefulness +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep." [GOC:dph, GOC:tb] +is_a: GO:0042749 ! regulation of circadian sleep/wake cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness +relationship: regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness + +[Term] +id: GO:0010841 +name: positive regulation of circadian sleep/wake cycle, wakefulness +namespace: biological_process +def: "Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010840 ! regulation of circadian sleep/wake cycle, wakefulness +is_a: GO:0042753 ! positive regulation of circadian rhythm +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness +relationship: positively_regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness + +[Term] +id: GO:0010842 +name: retina layer formation +namespace: biological_process +def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266] +synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb] +synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003407 ! neural retina development +relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye + +[Term] +id: GO:0010843 +name: obsolete promoter binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery." [GOC:dph, GOC:tb, SO:0000167] +comment: This term was made obsolete because the word "promoter" is used ambiguously in the literature. It sometimes is used to refer specifically to the "core promoter" region recognized by the basal transcription machinery, and other times is used to refer to a larger regulatory region composed of the core promoter and also the regulatory region adjacent (proximal) to the core promoter. The core promoter proximal region is typically recognized by "regulatory transcription factors", such as Gal4 in S. cerevisiae. +synonym: "DNA binding, transcription promoter" EXACT [GOC:dph, GOC:tb] +synonym: "promoter binding" EXACT [] +is_obsolete: true +consider: GO:0000976 +consider: GO:0001046 + +[Term] +id: GO:0010844 +name: recombination hotspot binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a region in a genome which promotes recombination." [GOC:dph, GOC:tb] +synonym: "DNA binding, recombination hotspot" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0010845 +name: positive regulation of reciprocal meiotic recombination +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +synonym: "positive regulation of meiotic recombination" RELATED [GOC:dph, GOC:tb] +is_a: GO:0010520 ! regulation of reciprocal meiotic recombination +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:0060903 ! positive regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007131 ! reciprocal meiotic recombination +relationship: positively_regulates GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0010846 +name: activation of reciprocal meiotic recombination +namespace: biological_process +def: "Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:dph, GOC:tb] +synonym: "activation of meiotic recombination" RELATED [GOC:dph, GOC:tb] +is_a: GO:0010845 ! positive regulation of reciprocal meiotic recombination + +[Term] +id: GO:0010847 +name: regulation of chromatin assembly +namespace: biological_process +def: "Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus." [GOC:dph, GOC:tb] +is_a: GO:0001672 ! regulation of chromatin assembly or disassembly +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031497 ! chromatin assembly +relationship: regulates GO:0031497 ! chromatin assembly + +[Term] +id: GO:0010848 +name: regulation of chromatin disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins." [GOC:dph, GOC:tb] +is_a: GO:0001672 ! regulation of chromatin assembly or disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031498 ! chromatin disassembly +relationship: regulates GO:0031498 ! chromatin disassembly + +[Term] +id: GO:0010849 +name: regulation of proton-transporting ATPase activity, rotational mechanism +namespace: biological_process +def: "Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism." [GOC:dph, GOC:tb] +synonym: "regulation of hydrogen ion transporting ATPase activity, rotational mechanism" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of V-type ATPase activity" BROAD [GOC:dph, GOC:tb] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046961 ! proton-transporting ATPase activity, rotational mechanism +relationship: regulates GO:0046961 ! proton-transporting ATPase activity, rotational mechanism + +[Term] +id: GO:0010850 +name: regulation of blood pressure by chemoreceptor signaling pathway +namespace: biological_process +def: "A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions." [GOC:dph, GOC:tb] +synonym: "regulation of blood pressure by chemoreceptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007165 ! signal transduction +is_a: GO:0008217 ! regulation of blood pressure + +[Term] +id: GO:0010851 +name: cyclase regulator activity +namespace: molecular_function +def: "Modulates the activity of an enzyme that catalyzes a ring closure reaction." [GOC:dph, GOC:tb] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0031279 ! regulation of cyclase activity + +[Term] +id: GO:0010852 +name: cyclase inhibitor activity +namespace: molecular_function +def: "Decreases the activity of an enzyme that catalyzes a ring closure reaction." [GOC:dph, GOC:tb] +is_a: GO:0010851 ! cyclase regulator activity +intersection_of: GO:0030234 ! enzyme regulator activity +intersection_of: negatively_regulates GO:0009975 ! cyclase activity +relationship: negatively_regulates GO:0009975 ! cyclase activity + +[Term] +id: GO:0010853 +name: cyclase activator activity +namespace: molecular_function +def: "Increases the activity of an enzyme that catalyzes a ring closure reaction." [GOC:dph, GOC:tb] +is_a: GO:0010851 ! cyclase regulator activity + +[Term] +id: GO:0010854 +name: adenylate cyclase regulator activity +namespace: molecular_function +def: "Modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate." [GOC:dph, GOC:tb] +is_a: GO:0010851 ! cyclase regulator activity + +[Term] +id: GO:0010855 +name: adenylate cyclase inhibitor activity +namespace: molecular_function +def: "Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate." [GOC:dph, GOC:tb] +is_a: GO:0010854 ! adenylate cyclase regulator activity + +[Term] +id: GO:0010856 +name: adenylate cyclase activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate." [GOC:dph, GOC:tb] +is_a: GO:0008047 ! enzyme activator activity + +[Term] +id: GO:0010857 +name: calcium-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium." [GOC:dph, GOC:tb] +xref: Reactome:R-HSA-8986937 "MECP2 is phosphorylated at T308" +xref: Reactome:R-HSA-9005561 "Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0010858 +name: calcium-dependent protein kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner." [GOC:dph, GOC:tb] +is_a: GO:0019887 ! protein kinase regulator activity + +[Term] +id: GO:0010859 +name: calcium-dependent cysteine-type endopeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner." [GOC:dph, GOC:tb] +is_a: GO:0004869 ! cysteine-type endopeptidase inhibitor activity + +[Term] +id: GO:0010860 +name: obsolete proteasome regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:dph, GOC:tb] +comment: The term was made obsolete because 'proteasome' is not a valid molecular function term. +synonym: "proteasome regulator activity" EXACT [] +is_obsolete: true +consider: GO:0061135 +consider: GO:0061136 + +[Term] +id: GO:0010862 +name: positive regulation of pathway-restricted SMAD protein phosphorylation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:dph, GOC:tb] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0060393 ! regulation of pathway-restricted SMAD protein phosphorylation +is_a: GO:0090100 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation +relationship: positively_regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation + +[Term] +id: GO:0010863 +name: positive regulation of phospholipase C activity +namespace: biological_process +def: "Any process that increases the rate of phospholipase C activity." [GOC:dph, GOC:tb] +is_a: GO:0010518 ! positive regulation of phospholipase activity +is_a: GO:1900274 ! regulation of phospholipase C activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004629 ! phospholipase C activity +relationship: positively_regulates GO:0004629 ! phospholipase C activity + +[Term] +id: GO:0010864 +name: positive regulation of protein histidine kinase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of protein histidine kinase activity." [GOC:dph, GOC:tb] +is_a: GO:0032110 ! regulation of protein histidine kinase activity +is_a: GO:0045860 ! positive regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004673 ! protein histidine kinase activity +relationship: positively_regulates GO:0004673 ! protein histidine kinase activity + +[Term] +id: GO:0010865 +name: stipule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms." [GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048366 ! leaf development + +[Term] +id: GO:0010866 +name: regulation of triglyceride biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol." [GOC:BHF, GOC:tb] +synonym: "regulation of triacylglycerol biosynthetic process" EXACT [GOC:mah] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:0090207 ! regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019432 ! triglyceride biosynthetic process +relationship: regulates GO:0019432 ! triglyceride biosynthetic process + +[Term] +id: GO:0010867 +name: positive regulation of triglyceride biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol." [GOC:BHF, GOC:tb] +synonym: "positive regulation of triacylglycerol biosynthetic process" EXACT [GOC:mah] +is_a: GO:0010866 ! regulation of triglyceride biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:0090208 ! positive regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019432 ! triglyceride biosynthetic process +relationship: positively_regulates GO:0019432 ! triglyceride biosynthetic process + +[Term] +id: GO:0010868 +name: negative regulation of triglyceride biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol." [GOC:BHF, GOC:tb] +synonym: "negative regulation of triacylglycerol biosynthetic process" EXACT [GOC:mah] +is_a: GO:0010866 ! regulation of triglyceride biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:0090209 ! negative regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019432 ! triglyceride biosynthetic process +relationship: negatively_regulates GO:0019432 ! triglyceride biosynthetic process + +[Term] +id: GO:0010869 +name: regulation of receptor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:BHF, GOC:tb] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032800 ! receptor biosynthetic process +relationship: regulates GO:0032800 ! receptor biosynthetic process + +[Term] +id: GO:0010870 +name: positive regulation of receptor biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:BHF, GOC:tb] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010869 ! regulation of receptor biosynthetic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032800 ! receptor biosynthetic process +relationship: positively_regulates GO:0032800 ! receptor biosynthetic process + +[Term] +id: GO:0010871 +name: negative regulation of receptor biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:BHF, GOC:tb] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0010869 ! regulation of receptor biosynthetic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032800 ! receptor biosynthetic process +relationship: negatively_regulates GO:0032800 ! receptor biosynthetic process + +[Term] +id: GO:0010872 +name: regulation of cholesterol esterification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle." [GOC:dph, GOC:tb] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034435 ! cholesterol esterification +relationship: regulates GO:0034435 ! cholesterol esterification + +[Term] +id: GO:0010873 +name: positive regulation of cholesterol esterification +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010872 ! regulation of cholesterol esterification +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045940 ! positive regulation of steroid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034435 ! cholesterol esterification +relationship: positively_regulates GO:0034435 ! cholesterol esterification + +[Term] +id: GO:0010874 +name: regulation of cholesterol efflux +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032374 ! regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033344 ! cholesterol efflux +relationship: regulates GO:0033344 ! cholesterol efflux + +[Term] +id: GO:0010875 +name: positive regulation of cholesterol efflux +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010874 ! regulation of cholesterol efflux +is_a: GO:0032376 ! positive regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033344 ! cholesterol efflux +relationship: positively_regulates GO:0033344 ! cholesterol efflux + +[Term] +id: GO:0010876 +name: lipid localization +namespace: biological_process +def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "lipid localisation" EXACT [GOC:mah] +is_a: GO:0033036 ! macromolecule localization + +[Term] +id: GO:0010877 +name: lipid transport involved in lipid storage +namespace: biological_process +def: "The directed movement of lipids into cells that is part of their accumulation and maintenance." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0006869 ! lipid transport +intersection_of: GO:0006869 ! lipid transport +intersection_of: part_of GO:0019915 ! lipid storage +relationship: part_of GO:0019915 ! lipid storage + +[Term] +id: GO:0010878 +name: cholesterol storage +namespace: biological_process +def: "The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "cholesterol sequestration" NARROW [GOC:dph, GOC:tb] +synonym: "sequestration of cholesterol" NARROW [GOC:dph, GOC:tb] +is_a: GO:0019915 ! lipid storage + +[Term] +id: GO:0010879 +name: cholesterol transport involved in cholesterol storage +namespace: biological_process +def: "The directed movement of cholesterol into cells that is part of their accumulation and maintenance." [GOC:dph, GOC:tb] +is_a: GO:0010877 ! lipid transport involved in lipid storage +is_a: GO:0030301 ! cholesterol transport +intersection_of: GO:0030301 ! cholesterol transport +intersection_of: part_of GO:0010878 ! cholesterol storage +relationship: part_of GO:0010878 ! cholesterol storage + +[Term] +id: GO:0010880 +name: regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014808 ! release of sequestered calcium ion into cytosol by sarcoplasmic reticulum +relationship: regulates GO:0014808 ! release of sequestered calcium ion into cytosol by sarcoplasmic reticulum + +[Term] +id: GO:0010881 +name: regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010880 ! regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum +is_a: GO:0010882 ! regulation of cardiac muscle contraction by calcium ion signaling + +[Term] +id: GO:0010882 +name: regulation of cardiac muscle contraction by calcium ion signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of cardiac muscle contraction by calcium ion signalling" EXACT [GOC:mah] +is_a: GO:0019722 ! calcium-mediated signaling +is_a: GO:0055117 ! regulation of cardiac muscle contraction +intersection_of: GO:0019722 ! calcium-mediated signaling +intersection_of: regulates GO:0060048 ! cardiac muscle contraction + +[Term] +id: GO:0010883 +name: regulation of lipid storage +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of lipid sequestration" NARROW [GOC:dph, GOC:tb] +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:1905952 ! regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019915 ! lipid storage +relationship: regulates GO:0019915 ! lipid storage + +[Term] +id: GO:0010884 +name: positive regulation of lipid storage +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of lipid sequestration" NARROW [GOC:dph, GOC:tb] +is_a: GO:0010883 ! regulation of lipid storage +is_a: GO:1905954 ! positive regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019915 ! lipid storage +relationship: positively_regulates GO:0019915 ! lipid storage + +[Term] +id: GO:0010885 +name: regulation of cholesterol storage +namespace: biological_process +def: "Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010883 ! regulation of lipid storage +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010878 ! cholesterol storage +relationship: regulates GO:0010878 ! cholesterol storage + +[Term] +id: GO:0010886 +name: positive regulation of cholesterol storage +namespace: biological_process +def: "Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of cholesterol sequestration" NARROW [GOC:dph, GOC:tb] +is_a: GO:0010884 ! positive regulation of lipid storage +is_a: GO:0010885 ! regulation of cholesterol storage +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010878 ! cholesterol storage +relationship: positively_regulates GO:0010878 ! cholesterol storage + +[Term] +id: GO:0010887 +name: negative regulation of cholesterol storage +namespace: biological_process +def: "Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of cholesterol sequestration" NARROW [GOC:dph, GOC:tb] +is_a: GO:0010885 ! regulation of cholesterol storage +is_a: GO:0010888 ! negative regulation of lipid storage +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010878 ! cholesterol storage +relationship: negatively_regulates GO:0010878 ! cholesterol storage + +[Term] +id: GO:0010888 +name: negative regulation of lipid storage +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010883 ! regulation of lipid storage +is_a: GO:1905953 ! negative regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019915 ! lipid storage +relationship: negatively_regulates GO:0019915 ! lipid storage + +[Term] +id: GO:0010889 +name: regulation of sequestering of triglyceride +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of sequestering of triacylglycerol" EXACT [GOC:mah] +synonym: "regulation of triacylglycerol sequestration" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010883 ! regulation of lipid storage +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030730 ! sequestering of triglyceride +relationship: regulates GO:0030730 ! sequestering of triglyceride + +[Term] +id: GO:0010890 +name: positive regulation of sequestering of triglyceride +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of sequestering of triacylglycerol" EXACT [GOC:mah] +synonym: "positive regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010884 ! positive regulation of lipid storage +is_a: GO:0010889 ! regulation of sequestering of triglyceride +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030730 ! sequestering of triglyceride +relationship: positively_regulates GO:0030730 ! sequestering of triglyceride + +[Term] +id: GO:0010891 +name: negative regulation of sequestering of triglyceride +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of sequestering of triacylglycerol" EXACT [GOC:mah] +synonym: "negative regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010888 ! negative regulation of lipid storage +is_a: GO:0010889 ! regulation of sequestering of triglyceride +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030730 ! sequestering of triglyceride +relationship: negatively_regulates GO:0030730 ! sequestering of triglyceride + +[Term] +id: GO:0010892 +name: positive regulation of mitochondrial translation in response to stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress." [GOC:dph, GOC:jp, GOC:tb, PMID:8830768] +is_a: GO:0032056 ! positive regulation of translation in response to stress +is_a: GO:0070131 ! positive regulation of mitochondrial translation + +[Term] +id: GO:0010893 +name: positive regulation of steroid biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb] +is_a: GO:0045940 ! positive regulation of steroid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006694 ! steroid biosynthetic process +relationship: positively_regulates GO:0006694 ! steroid biosynthetic process + +[Term] +id: GO:0010894 +name: negative regulation of steroid biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb] +is_a: GO:0045939 ! negative regulation of steroid metabolic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006694 ! steroid biosynthetic process +relationship: negatively_regulates GO:0006694 ! steroid biosynthetic process + +[Term] +id: GO:0010895 +name: negative regulation of ergosterol biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol." [GOC:tb] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0032443 ! regulation of ergosterol biosynthetic process +is_a: GO:0106119 ! negative regulation of sterol biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006696 ! ergosterol biosynthetic process +relationship: negatively_regulates GO:0006696 ! ergosterol biosynthetic process + +[Term] +id: GO:0010896 +name: regulation of triglyceride catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride." [GOC:rn, GOC:tb] +synonym: "regulation of triacylglycerol catabolic process" EXACT [GOC:mah] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:0090207 ! regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019433 ! triglyceride catabolic process +relationship: regulates GO:0019433 ! triglyceride catabolic process + +[Term] +id: GO:0010897 +name: negative regulation of triglyceride catabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride." [GOC:rn, GOC:tb] +synonym: "negative regulation of triacylglycerol catabolic process" EXACT [GOC:mah] +is_a: GO:0010896 ! regulation of triglyceride catabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:0090209 ! negative regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019433 ! triglyceride catabolic process +relationship: negatively_regulates GO:0019433 ! triglyceride catabolic process + +[Term] +id: GO:0010898 +name: positive regulation of triglyceride catabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride." [GOC:rn, GOC:tb] +synonym: "positive regulation of triacylglycerol catabolic process" EXACT [GOC:mah] +is_a: GO:0010896 ! regulation of triglyceride catabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:0090208 ! positive regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019433 ! triglyceride catabolic process +relationship: positively_regulates GO:0019433 ! triglyceride catabolic process + +[Term] +id: GO:0010899 +name: regulation of phosphatidylcholine catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:BHF, GOC:tb] +is_a: GO:0060696 ! regulation of phospholipid catabolic process +is_a: GO:0150172 ! regulation of phosphatidylcholine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034638 ! phosphatidylcholine catabolic process +relationship: regulates GO:0034638 ! phosphatidylcholine catabolic process + +[Term] +id: GO:0010900 +name: negative regulation of phosphatidylcholine catabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:BHF, GOC:tb] +is_a: GO:0010899 ! regulation of phosphatidylcholine catabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034638 ! phosphatidylcholine catabolic process +relationship: negatively_regulates GO:0034638 ! phosphatidylcholine catabolic process + +[Term] +id: GO:0010901 +name: regulation of very-low-density lipoprotein particle remodeling +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:tb] +synonym: "regulation of VLDL remodeling" EXACT [GOC:tb] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034372 ! very-low-density lipoprotein particle remodeling +relationship: regulates GO:0034372 ! very-low-density lipoprotein particle remodeling + +[Term] +id: GO:0010902 +name: positive regulation of very-low-density lipoprotein particle remodeling +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:tb] +synonym: "positive regulation of VLDL remodeling" EXACT [GOC:tb] +is_a: GO:0010901 ! regulation of very-low-density lipoprotein particle remodeling +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034372 ! very-low-density lipoprotein particle remodeling +relationship: positively_regulates GO:0034372 ! very-low-density lipoprotein particle remodeling + +[Term] +id: GO:0010903 +name: negative regulation of very-low-density lipoprotein particle remodeling +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:tb] +synonym: "negative regulation of VLDL remodeling" EXACT [GOC:tb] +is_a: GO:0010901 ! regulation of very-low-density lipoprotein particle remodeling +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034372 ! very-low-density lipoprotein particle remodeling +relationship: negatively_regulates GO:0034372 ! very-low-density lipoprotein particle remodeling + +[Term] +id: GO:0010904 +name: regulation of UDP-glucose catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:BHF, GOC:tb] +synonym: "regulation of UDP-glucose catabolism" EXACT [GOC:tb] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0051174 ! regulation of phosphorus metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006258 ! UDP-glucose catabolic process +relationship: regulates GO:0006258 ! UDP-glucose catabolic process + +[Term] +id: GO:0010905 +name: negative regulation of UDP-glucose catabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:BHF, GOC:tb] +synonym: "negative regulation of UDP-glucose catabolism" EXACT [GOC:tb] +is_a: GO:0010563 ! negative regulation of phosphorus metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0010904 ! regulation of UDP-glucose catabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006258 ! UDP-glucose catabolic process +relationship: negatively_regulates GO:0006258 ! UDP-glucose catabolic process + +[Term] +id: GO:0010906 +name: regulation of glucose metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] +synonym: "regulation of glucose metabolism" EXACT [GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006006 ! glucose metabolic process +relationship: regulates GO:0006006 ! glucose metabolic process + +[Term] +id: GO:0010907 +name: positive regulation of glucose metabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] +synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006006 ! glucose metabolic process +relationship: positively_regulates GO:0006006 ! glucose metabolic process + +[Term] +id: GO:0010908 +name: regulation of heparan sulfate proteoglycan biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues." [GOC:dph, GOC:tb] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015012 ! heparan sulfate proteoglycan biosynthetic process +relationship: regulates GO:0015012 ! heparan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0010909 +name: positive regulation of heparan sulfate proteoglycan biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues." [GOC:dph, GOC:tb] +is_a: GO:0010908 ! regulation of heparan sulfate proteoglycan biosynthetic process +is_a: GO:1902730 ! positive regulation of proteoglycan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015012 ! heparan sulfate proteoglycan biosynthetic process +relationship: positively_regulates GO:0015012 ! heparan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0010910 +name: positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate." [GOC:dph, GOC:tb] +is_a: GO:0010909 ! positive regulation of heparan sulfate proteoglycan biosynthetic process +is_a: GO:0010912 ! positive regulation of isomerase activity + +[Term] +id: GO:0010911 +name: regulation of isomerase activity +namespace: biological_process +def: "Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5." [GOC:dph, GOC:tb] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016853 ! isomerase activity +relationship: regulates GO:0016853 ! isomerase activity + +[Term] +id: GO:0010912 +name: positive regulation of isomerase activity +namespace: biological_process +def: "Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5." [GOC:dph, GOC:tb] +is_a: GO:0010911 ! regulation of isomerase activity +is_a: GO:0043085 ! positive regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016853 ! isomerase activity +relationship: positively_regulates GO:0016853 ! isomerase activity + +[Term] +id: GO:0010913 +name: regulation of sterigmatocystin biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds." [GOC:dph, GOC:tb] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045461 ! sterigmatocystin biosynthetic process +relationship: regulates GO:0045461 ! sterigmatocystin biosynthetic process + +[Term] +id: GO:0010914 +name: positive regulation of sterigmatocystin biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds." [GOC:dph, GOC:tb] +is_a: GO:0010913 ! regulation of sterigmatocystin biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045461 ! sterigmatocystin biosynthetic process +relationship: positively_regulates GO:0045461 ! sterigmatocystin biosynthetic process + +[Term] +id: GO:0010915 +name: regulation of very-low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of VLDL clearance" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of VLDL particle clearance" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034447 ! very-low-density lipoprotein particle clearance +relationship: regulates GO:0034447 ! very-low-density lipoprotein particle clearance + +[Term] +id: GO:0010916 +name: negative regulation of very-low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of VLDL clearance" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of VLDL particle clearance" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010915 ! regulation of very-low-density lipoprotein particle clearance +is_a: GO:0010985 ! negative regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034447 ! very-low-density lipoprotein particle clearance +relationship: negatively_regulates GO:0034447 ! very-low-density lipoprotein particle clearance + +[Term] +id: GO:0010917 +name: negative regulation of mitochondrial membrane potential +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:dph, GOC:tb] +synonym: "reduction of mitochondrial membrane potential" EXACT [GOC:rph] +is_a: GO:0045837 ! negative regulation of membrane potential +is_a: GO:0051881 ! regulation of mitochondrial membrane potential + +[Term] +id: GO:0010918 +name: positive regulation of mitochondrial membrane potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:dph, GOC:tb] +synonym: "elevation of mitochondrial membrane potential" EXACT [GOC:rph] +is_a: GO:0045838 ! positive regulation of membrane potential +is_a: GO:0051881 ! regulation of mitochondrial membrane potential + +[Term] +id: GO:0010919 +name: regulation of inositol phosphate biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of inositol phosphate biosynthesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0019220 ! regulation of phosphate metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032958 ! inositol phosphate biosynthetic process +relationship: regulates GO:0032958 ! inositol phosphate biosynthetic process + +[Term] +id: GO:0010920 +name: negative regulation of inositol phosphate biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:dph, GOC:tb] +synonym: "negative regulation of inositol phosphate biosynthesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0010919 ! regulation of inositol phosphate biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032958 ! inositol phosphate biosynthetic process +relationship: negatively_regulates GO:0032958 ! inositol phosphate biosynthetic process + +[Term] +id: GO:0010921 +name: regulation of phosphatase activity +namespace: biological_process +def: "Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0035303 ! regulation of dephosphorylation +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016791 ! phosphatase activity +relationship: regulates GO:0016791 ! phosphatase activity + +[Term] +id: GO:0010922 +name: positive regulation of phosphatase activity +namespace: biological_process +def: "Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010921 ! regulation of phosphatase activity +is_a: GO:0035306 ! positive regulation of dephosphorylation +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016791 ! phosphatase activity +relationship: positively_regulates GO:0016791 ! phosphatase activity + +[Term] +id: GO:0010923 +name: negative regulation of phosphatase activity +namespace: biological_process +def: "Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010921 ! regulation of phosphatase activity +is_a: GO:0035305 ! negative regulation of dephosphorylation +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016791 ! phosphatase activity +relationship: negatively_regulates GO:0016791 ! phosphatase activity + +[Term] +id: GO:0010924 +name: regulation of inositol-polyphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004445 ! inositol-polyphosphate 5-phosphatase activity +relationship: regulates GO:0004445 ! inositol-polyphosphate 5-phosphatase activity + +[Term] +id: GO:0010925 +name: positive regulation of inositol-polyphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:0010924 ! regulation of inositol-polyphosphate 5-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004445 ! inositol-polyphosphate 5-phosphatase activity +relationship: positively_regulates GO:0004445 ! inositol-polyphosphate 5-phosphatase activity + +[Term] +id: GO:0010926 +name: obsolete anatomical structure formation +namespace: biological_process +def: "OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:tb] +comment: The reason for obsoletion is that the term is confusing - it sounds developmental and has a developmental sounding def, but it is not a child of developmental process and its children included 'cellular component assembly'. The term was created to group together 'cellular component assembly' and 'anatomical structure formation involved in morphogenesis', but we no longer feel that this grouping is useful. +synonym: "anatomical structure formation" EXACT [] +is_obsolete: true +consider: GO:0022607 +consider: GO:0048646 + +[Term] +id: GO:0010927 +name: cellular component assembly involved in morphogenesis +namespace: biological_process +def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +intersection_of: GO:0022607 ! cellular component assembly +intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0032989 ! cellular component morphogenesis + +[Term] +id: GO:0010928 +name: regulation of auxin mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin." [GOC:dph, GOC:tb] +synonym: "regulation of auxin mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009734 ! auxin-activated signaling pathway +relationship: regulates GO:0009734 ! auxin-activated signaling pathway + +[Term] +id: GO:0010929 +name: positive regulation of auxin mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin." [GOC:dph, GOC:tb] +synonym: "positive regulation of auxin mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0010928 ! regulation of auxin mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009734 ! auxin-activated signaling pathway +relationship: positively_regulates GO:0009734 ! auxin-activated signaling pathway + +[Term] +id: GO:0010930 +name: negative regulation of auxin mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin." [GOC:dph, GOC:tb] +synonym: "negative regulation of auxin mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0010928 ! regulation of auxin mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009734 ! auxin-activated signaling pathway +relationship: negatively_regulates GO:0009734 ! auxin-activated signaling pathway + +[Term] +id: GO:0010931 +name: macrophage tolerance induction +namespace: biological_process +def: "A process involving any mechanism for tolerance induction in macrophages." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002507 ! tolerance induction + +[Term] +id: GO:0010932 +name: regulation of macrophage tolerance induction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of macrophage tolerance induction." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002643 ! regulation of tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010931 ! macrophage tolerance induction +relationship: regulates GO:0010931 ! macrophage tolerance induction + +[Term] +id: GO:0010933 +name: positive regulation of macrophage tolerance induction +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of B cell tolerance induction." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0002645 ! positive regulation of tolerance induction +is_a: GO:0010932 ! regulation of macrophage tolerance induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010931 ! macrophage tolerance induction +relationship: positively_regulates GO:0010931 ! macrophage tolerance induction + +[Term] +id: GO:0010934 +name: macrophage cytokine production +namespace: biological_process +def: "The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +is_a: GO:0061082 ! myeloid leukocyte cytokine production + +[Term] +id: GO:0010935 +name: regulation of macrophage cytokine production +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:rl] +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010934 ! macrophage cytokine production +relationship: regulates GO:0010934 ! macrophage cytokine production + +[Term] +id: GO:0010936 +name: negative regulation of macrophage cytokine production +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:rl] +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0010935 ! regulation of macrophage cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010934 ! macrophage cytokine production +relationship: negatively_regulates GO:0010934 ! macrophage cytokine production + +[Term] +id: GO:0010937 +name: regulation of cytoplasmic microtubule depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb] +is_a: GO:0031114 ! regulation of microtubule depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010938 ! cytoplasmic microtubule depolymerization +relationship: regulates GO:0010938 ! cytoplasmic microtubule depolymerization + +[Term] +id: GO:0010938 +name: cytoplasmic microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb] +is_a: GO:0007019 ! microtubule depolymerization +is_a: GO:0031122 ! cytoplasmic microtubule organization +intersection_of: GO:0007019 ! microtubule depolymerization +intersection_of: occurs_in GO:0005737 ! cytoplasm +relationship: occurs_in GO:0005737 ! cytoplasm + +[Term] +id: GO:0010939 +name: regulation of necrotic cell death +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [PMID:16507998] +is_a: GO:0010941 ! regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070265 ! necrotic cell death +relationship: regulates GO:0070265 ! necrotic cell death + +[Term] +id: GO:0010940 +name: positive regulation of necrotic cell death +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [PMID:16507998] +is_a: GO:0010939 ! regulation of necrotic cell death +is_a: GO:0010942 ! positive regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070265 ! necrotic cell death +relationship: positively_regulates GO:0070265 ! necrotic cell death + +[Term] +id: GO:0010941 +name: regulation of cell death +namespace: biological_process +def: "Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:dph, GOC:tb] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008219 ! cell death +relationship: regulates GO:0008219 ! cell death + +[Term] +id: GO:0010942 +name: positive regulation of cell death +namespace: biological_process +def: "Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:dph, GOC:tb] +is_a: GO:0010941 ! regulation of cell death +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008219 ! cell death +relationship: positively_regulates GO:0008219 ! cell death + +[Term] +id: GO:0010943 +name: NADPH pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H2O = NMNH + ADP." [GOC:tb] +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0010944 +name: negative regulation of transcription by competitive promoter binding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site." [GOC:tb] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated + +[Term] +id: GO:0010945 +name: CoA pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme A + H2O = 3',5'-ADP + 4'-phosphopantetheine." [GOC:tb] +is_a: GO:0016462 ! pyrophosphatase activity +created_by: tb +creation_date: 2009-04-22T02:06:40Z + +[Term] +id: GO:0010946 +name: regulation of meiotic joint molecule formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination." [GOC:dph, GOC:tb] +is_a: GO:0010520 ! regulation of reciprocal meiotic recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000709 ! meiotic joint molecule formation +relationship: regulates GO:0000709 ! meiotic joint molecule formation +created_by: tb +creation_date: 2009-04-27T09:46:23Z + +[Term] +id: GO:0010947 +name: negative regulation of meiotic joint molecule formation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination." [GOC:dph, GOC:tb] +is_a: GO:0010946 ! regulation of meiotic joint molecule formation +is_a: GO:0045128 ! negative regulation of reciprocal meiotic recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000709 ! meiotic joint molecule formation +relationship: negatively_regulates GO:0000709 ! meiotic joint molecule formation +created_by: tb +creation_date: 2009-04-27T09:48:53Z + +[Term] +id: GO:0010948 +name: negative regulation of cell cycle process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0045786 ! negative regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022402 ! cell cycle process +relationship: negatively_regulates GO:0022402 ! cell cycle process +created_by: tb +creation_date: 2009-04-27T09:53:22Z + +[Term] +id: GO:0010949 +name: negative regulation of intestinal phytosterol absorption +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:1904730 ! negative regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060752 ! intestinal phytosterol absorption +relationship: negatively_regulates GO:0060752 ! intestinal phytosterol absorption +created_by: tb +creation_date: 2009-04-27T11:02:06Z + +[Term] +id: GO:0010950 +name: positive regulation of endopeptidase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] +is_a: GO:0010952 ! positive regulation of peptidase activity +is_a: GO:0052548 ! regulation of endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004175 ! endopeptidase activity +relationship: positively_regulates GO:0004175 ! endopeptidase activity +created_by: tb +creation_date: 2009-04-27T11:45:39Z + +[Term] +id: GO:0010951 +name: negative regulation of endopeptidase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] +subset: goslim_chembl +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:0052548 ! regulation of endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004175 ! endopeptidase activity +relationship: negatively_regulates GO:0004175 ! endopeptidase activity +created_by: tb +creation_date: 2009-04-27T11:47:01Z + +[Term] +id: GO:0010952 +name: positive regulation of peptidase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008233 ! peptidase activity +relationship: positively_regulates GO:0008233 ! peptidase activity +created_by: tb +creation_date: 2009-04-27T11:54:32Z + +[Term] +id: GO:0010954 +name: positive regulation of protein processing +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage." [GOC:dph, GOC:mah, GOC:tb] +synonym: "positive regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:0070613 ! regulation of protein processing +is_a: GO:1903319 ! positive regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016485 ! protein processing +relationship: positively_regulates GO:0016485 ! protein processing +created_by: tb +creation_date: 2009-04-27T12:09:13Z + +[Term] +id: GO:0010955 +name: negative regulation of protein processing +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage." [GOC:dph, GOC:mah, GOC:tb] +synonym: "negative regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:0070613 ! regulation of protein processing +is_a: GO:1903318 ! negative regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016485 ! protein processing +relationship: negatively_regulates GO:0016485 ! protein processing +created_by: tb +creation_date: 2009-04-27T12:10:19Z + +[Term] +id: GO:0010956 +name: negative regulation of calcidiol 1-monooxygenase activity +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010957 ! negative regulation of vitamin D biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0032769 ! negative regulation of monooxygenase activity +is_a: GO:0060558 ! regulation of calcidiol 1-monooxygenase activity +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004498 ! calcidiol 1-monooxygenase activity +relationship: negatively_regulates GO:0004498 ! calcidiol 1-monooxygenase activity +created_by: tb +creation_date: 2009-05-06T11:21:34Z + +[Term] +id: GO:0010957 +name: negative regulation of vitamin D biosynthetic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0060556 ! regulation of vitamin D biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042368 ! vitamin D biosynthetic process +relationship: negatively_regulates GO:0042368 ! vitamin D biosynthetic process +created_by: tb +creation_date: 2009-05-06T11:25:12Z + +[Term] +id: GO:0010958 +name: regulation of amino acid import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amino acid import into a cell." [GOC:dph, GOC:tb] +synonym: "regulation of amino acid import" BROAD [] +is_a: GO:1903789 ! regulation of amino acid transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0089718 ! amino acid import across plasma membrane +relationship: regulates GO:0089718 ! amino acid import across plasma membrane +created_by: tb +creation_date: 2009-05-06T11:33:12Z + +[Term] +id: GO:0010959 +name: regulation of metal ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0043269 ! regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030001 ! metal ion transport +relationship: regulates GO:0030001 ! metal ion transport +created_by: tb +creation_date: 2009-05-06T11:40:55Z + +[Term] +id: GO:0010960 +name: magnesium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell." [GOC:dph, GOC:tb] +is_a: GO:0055065 ! metal ion homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis +created_by: tb +creation_date: 2009-05-06T11:47:17Z + +[Term] +id: GO:0010961 +name: cellular magnesium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell." [GOC:dph, GOC:tb] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0010960 ! magnesium ion homeostasis +is_a: GO:0072503 ! cellular divalent inorganic cation homeostasis +created_by: tb +creation_date: 2009-05-06T11:48:45Z + +[Term] +id: GO:0010962 +name: regulation of glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009250 ! glucan biosynthetic process +relationship: regulates GO:0009250 ! glucan biosynthetic process +created_by: tb +creation_date: 2009-05-11T12:17:53Z + +[Term] +id: GO:0010963 +name: regulation of L-arginine import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle." [GOC:dph, GOC:tb] +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902023 ! L-arginine transport +relationship: regulates GO:1902023 ! L-arginine transport +created_by: tb +creation_date: 2009-05-20T11:20:18Z + +[Term] +id: GO:0010964 +name: regulation of heterochromatin assembly by small RNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heterochromatin assembly by small RNA." [GOC:dph, GOC:tb] +synonym: "regulation of chromatin silencing by small RNA" RELATED [] +synonym: "regulation of RNAi-mediated heterochromatin assembly" EXACT [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031048 ! heterochromatin assembly by small RNA +relationship: regulates GO:0031048 ! heterochromatin assembly by small RNA +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: tb +creation_date: 2009-05-20T11:25:42Z + +[Term] +id: GO:0010965 +name: regulation of mitotic sister chromatid separation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." [GOC:dph, GOC:tb] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:1905818 ! regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051306 ! mitotic sister chromatid separation +relationship: regulates GO:0051306 ! mitotic sister chromatid separation +created_by: tb +creation_date: 2009-05-20T11:39:07Z + +[Term] +id: GO:0010966 +name: regulation of phosphate transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006817 ! phosphate ion transport +relationship: regulates GO:0006817 ! phosphate ion transport +created_by: tb +creation_date: 2009-05-20T11:42:50Z + +[Term] +id: GO:0010967 +name: regulation of polyamine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups." [GOC:dph, GOC:tb] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006596 ! polyamine biosynthetic process +relationship: regulates GO:0006596 ! polyamine biosynthetic process +created_by: tb +creation_date: 2009-05-20T11:45:37Z + +[Term] +id: GO:0010968 +name: regulation of microtubule nucleation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] +is_a: GO:0031113 ! regulation of microtubule polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007020 ! microtubule nucleation +relationship: regulates GO:0007020 ! microtubule nucleation +created_by: tb +creation_date: 2009-05-20T11:51:21Z + +[Term] +id: GO:0010969 +name: regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0060238 ! regulation of signal transduction involved in conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +relationship: regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +created_by: tb +creation_date: 2009-05-20T11:54:57Z + +[Term] +id: GO:0010970 +name: transport along microtubule +namespace: biological_process +def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb] +synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph] +synonym: "microtubule-based transport" BROAD [] +synonym: "movement along microtubule" EXACT [] +is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport +is_a: GO:0099111 ! microtubule-based transport +created_by: tb +creation_date: 2009-05-27T10:56:08Z + +[Term] +id: GO:0010971 +name: positive regulation of G2/M transition of mitotic cell cycle +namespace: biological_process +alt_id: GO:0031662 +def: "Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." [GOC:dph, GOC:mtg_cell_cycle, GOC:tb] +synonym: "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle" RELATED [] +synonym: "positive regulation of mitotic entry" EXACT [GOC:mah] +is_a: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle +is_a: GO:1901992 ! positive regulation of mitotic cell cycle phase transition +is_a: GO:1902751 ! positive regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000086 ! G2/M transition of mitotic cell cycle +relationship: positively_regulates GO:0000086 ! G2/M transition of mitotic cell cycle +created_by: tb +creation_date: 2009-06-01T10:16:34Z + +[Term] +id: GO:0010972 +name: negative regulation of G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] +synonym: "negative regulation of mitotic entry" EXACT [GOC:vw] +is_a: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle +is_a: GO:1901991 ! negative regulation of mitotic cell cycle phase transition +is_a: GO:1902750 ! negative regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000086 ! G2/M transition of mitotic cell cycle +relationship: negatively_regulates GO:0000086 ! G2/M transition of mitotic cell cycle +created_by: tb +creation_date: 2009-06-01T10:18:29Z + +[Term] +id: GO:0010973 +name: positive regulation of division septum assembly +namespace: biological_process +alt_id: GO:1901912 +alt_id: GO:1902470 +def: "Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [GOC:mtg_cell_cycle, PMID:19959363, PMID:21246752, PMID:22786806] +synonym: "positive regulation of division septum formation" EXACT [] +synonym: "positive regulation of division septum formation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic division septum assembly" EXACT [GOC:TermGenie] +is_a: GO:0032955 ! regulation of division septum assembly +is_a: GO:1901893 ! positive regulation of cell septum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000917 ! division septum assembly +relationship: positively_regulates GO:0000917 ! division septum assembly +created_by: tb +creation_date: 2009-06-01T10:27:15Z + +[Term] +id: GO:0010974 +name: negative regulation of division septum assembly +namespace: biological_process +alt_id: GO:1901139 +alt_id: GO:1902469 +def: "Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [GOC:mtg_cell_cycle, PMID:19959363, PMID:21246752, PMID:22786806] +synonym: "inhibition of division septum assembly involved in cell cycle cytokinesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of division septum formation" EXACT [] +is_a: GO:0032955 ! regulation of division septum assembly +is_a: GO:1901892 ! negative regulation of cell septum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000917 ! division septum assembly +relationship: negatively_regulates GO:0000917 ! division septum assembly +created_by: tb +creation_date: 2009-06-01T10:32:32Z + +[Term] +id: GO:0010975 +name: regulation of neuron projection development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] +synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah] +synonym: "regulation of neurite development" NARROW [GOC:mah] +synonym: "regulation of neurite formation" NARROW [GOC:mah] +synonym: "regulation of neurite growth" NARROW [GOC:mah] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031175 ! neuron projection development +relationship: regulates GO:0031175 ! neuron projection development +created_by: tb +creation_date: 2009-06-01T10:44:45Z + +[Term] +id: GO:0010976 +name: positive regulation of neuron projection development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] +synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah] +synonym: "positive regulation of neurite development" NARROW [GOC:mah] +synonym: "positive regulation of neurite formation" NARROW [GOC:mah] +synonym: "positive regulation of neurite growth" NARROW [GOC:mah] +is_a: GO:0010975 ! regulation of neuron projection development +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0045666 ! positive regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031175 ! neuron projection development +relationship: positively_regulates GO:0031175 ! neuron projection development +created_by: tb +creation_date: 2009-06-01T10:46:44Z + +[Term] +id: GO:0010977 +name: negative regulation of neuron projection development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] +synonym: "growth cone collapse" RELATED [GOC:pr] +synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah] +synonym: "negative regulation of neurite development" NARROW [GOC:mah] +synonym: "negative regulation of neurite formation" NARROW [GOC:mah] +synonym: "negative regulation of neurite growth" NARROW [GOC:mah] +is_a: GO:0010975 ! regulation of neuron projection development +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0045665 ! negative regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031175 ! neuron projection development +relationship: negatively_regulates GO:0031175 ! neuron projection development +created_by: tb +creation_date: 2009-06-01T10:47:42Z + +[Term] +id: GO:0010978 +name: gene silencing involved in chronological cell aging +namespace: biological_process +def: "Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0016458 ! gene silencing +intersection_of: GO:0016458 ! gene silencing +intersection_of: part_of GO:0001300 ! chronological cell aging +relationship: part_of GO:0001300 ! chronological cell aging +created_by: tb +creation_date: 2009-06-01T11:39:42Z + +[Term] +id: GO:0010979 +name: regulation of vitamin D 24-hydroxylase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032768 ! regulation of monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070576 ! vitamin D 24-hydroxylase activity +relationship: regulates GO:0070576 ! vitamin D 24-hydroxylase activity +created_by: tb +creation_date: 2009-06-01T11:44:54Z + +[Term] +id: GO:0010980 +name: positive regulation of vitamin D 24-hydroxylase activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010979 ! regulation of vitamin D 24-hydroxylase activity +is_a: GO:0032770 ! positive regulation of monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070576 ! vitamin D 24-hydroxylase activity +relationship: positively_regulates GO:0070576 ! vitamin D 24-hydroxylase activity +created_by: tb +creation_date: 2009-06-01T11:47:19Z + +[Term] +id: GO:0010981 +name: regulation of cell wall macromolecule metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:dph, GOC:tb] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044036 ! cell wall macromolecule metabolic process +relationship: regulates GO:0044036 ! cell wall macromolecule metabolic process +created_by: tb +creation_date: 2009-06-01T11:55:35Z + +[Term] +id: GO:0010982 +name: regulation of high-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034384 ! high-density lipoprotein particle clearance +relationship: regulates GO:0034384 ! high-density lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:01:30Z + +[Term] +id: GO:0010983 +name: positive regulation of high-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010982 ! regulation of high-density lipoprotein particle clearance +is_a: GO:0010986 ! positive regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034384 ! high-density lipoprotein particle clearance +relationship: positively_regulates GO:0034384 ! high-density lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:03:32Z + +[Term] +id: GO:0010984 +name: regulation of lipoprotein particle clearance +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034381 ! plasma lipoprotein particle clearance +relationship: regulates GO:0034381 ! plasma lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:05:12Z + +[Term] +id: GO:0010985 +name: negative regulation of lipoprotein particle clearance +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034381 ! plasma lipoprotein particle clearance +relationship: negatively_regulates GO:0034381 ! plasma lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:06:59Z + +[Term] +id: GO:0010986 +name: positive regulation of lipoprotein particle clearance +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034381 ! plasma lipoprotein particle clearance +relationship: positively_regulates GO:0034381 ! plasma lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:08:19Z + +[Term] +id: GO:0010987 +name: negative regulation of high-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010982 ! regulation of high-density lipoprotein particle clearance +is_a: GO:0010985 ! negative regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034384 ! high-density lipoprotein particle clearance +relationship: negatively_regulates GO:0034384 ! high-density lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:09:36Z + +[Term] +id: GO:0010988 +name: regulation of low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034383 ! low-density lipoprotein particle clearance +relationship: regulates GO:0034383 ! low-density lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:13:07Z + +[Term] +id: GO:0010989 +name: negative regulation of low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010985 ! negative regulation of lipoprotein particle clearance +is_a: GO:0010988 ! regulation of low-density lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034383 ! low-density lipoprotein particle clearance +relationship: negatively_regulates GO:0034383 ! low-density lipoprotein particle clearance +created_by: tb +creation_date: 2009-06-01T12:15:07Z + +[Term] +id: GO:0010990 +name: regulation of SMAD protein complex assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007183 ! SMAD protein complex assembly +relationship: regulates GO:0007183 ! SMAD protein complex assembly +created_by: tb +creation_date: 2009-06-03T11:28:05Z + +[Term] +id: GO:0010991 +name: negative regulation of SMAD protein complex assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010990 ! regulation of SMAD protein complex assembly +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007183 ! SMAD protein complex assembly +relationship: negatively_regulates GO:0007183 ! SMAD protein complex assembly +created_by: tb +creation_date: 2009-06-03T11:30:44Z + +[Term] +id: GO:0010992 +name: ubiquitin recycling +namespace: biological_process +alt_id: GO:0010993 +def: "Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates." [GOC:BHF, GOC:dph, GOC:PG, GOC:tb, PMID:19410548] +synonym: "regulation of ubiquitin homeostasis" NARROW [] +synonym: "ubiquitin homeostasis" RELATED [] +is_a: GO:0019725 ! cellular homeostasis +created_by: tb +creation_date: 2009-06-03T11:36:55Z + +[Term] +id: GO:0010994 +name: free ubiquitin chain polymerization +namespace: biological_process +def: "The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051258 ! protein polymerization +relationship: part_of GO:0010992 ! ubiquitin recycling +created_by: tb +creation_date: 2009-06-03T11:41:03Z + +[Term] +id: GO:0010995 +name: free ubiquitin chain depolymerization +namespace: biological_process +def: "The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051261 ! protein depolymerization +relationship: part_of GO:0010992 ! ubiquitin recycling +created_by: tb +creation_date: 2009-06-03T11:45:42Z + +[Term] +id: GO:0010996 +name: response to auditory stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus." [GOC:BHF, GOC:dph, GOC:sl, GOC:tb] +synonym: "response to sound" EXACT [GOC:dph, GOC:sl, GOC:tb] +synonym: "response to sound stimulus" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009612 ! response to mechanical stimulus +created_by: tb +creation_date: 2009-06-10T11:09:38Z + +[Term] +id: GO:0010997 +name: anaphase-promoting complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "APC binding" EXACT [GOC:dph, GOC:tb] +is_a: GO:0044877 ! protein-containing complex binding +created_by: tb +creation_date: 2009-06-10T11:18:22Z + +[Term] +id: GO:0010998 +name: regulation of translational initiation by eIF2 alpha phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha." [GOC:BHF, GOC:dph, GOC:hjd, GOC:tb] +comment: Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'. +synonym: "eIF2 alpha phosphorylation in response to stress" EXACT [GOC:bf] +synonym: "regulation of translational initiation by eIF2 alpha phosphorylation in response to stress" EXACT [GOC:bf] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0043558 ! regulation of translational initiation in response to stress +created_by: tb +creation_date: 2009-06-10T11:27:47Z + +[Term] +id: GO:0010999 +name: regulation of eIF2 alpha phosphorylation by heme +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0080135 ! regulation of cellular response to stress +relationship: regulates GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation +created_by: tb +creation_date: 2009-06-10T11:42:10Z + +[Term] +id: GO:0011000 +name: replication fork arrest at mating type locus +namespace: biological_process +def: "A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus." [GOC:dph, GOC:tb] +is_a: GO:0043111 ! replication fork arrest +created_by: tb +creation_date: 2009-06-24T12:02:48Z + +[Term] +id: GO:0012501 +name: programmed cell death +namespace: biological_process +alt_id: GO:0016244 +def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] +comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. +synonym: "caspase-independent apoptosis" RELATED [] +synonym: "caspase-independent cell death" NARROW [] +synonym: "non-apoptotic programmed cell death" NARROW [] +synonym: "nonapoptotic programmed cell death" NARROW [] +synonym: "PCD" RELATED [] +synonym: "RCD" RELATED [] +synonym: "regulated cell death" BROAD [] +xref: Wikipedia:Programmed_cell_death +is_a: GO:0008219 ! cell death + +[Term] +id: GO:0012502 +name: induction of programmed cell death +namespace: biological_process +alt_id: GO:0012503 +def: "A process which directly activates any of the steps required for programmed cell death." [GOC:lr] +synonym: "induction of non-apoptotic programmed cell death" NARROW [] +synonym: "induction of nonapoptotic programmed cell death" NARROW [] +is_a: GO:0043068 ! positive regulation of programmed cell death + +[Term] +id: GO:0012505 +name: endomembrane system +namespace: cellular_component +def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_flybase_ribbon +subset: goslim_yeast +xref: Wikipedia:Endomembrane_system +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005773 ! vacuole +relationship: has_part GO:0005886 ! plasma membrane + +[Term] +id: GO:0012506 +name: vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle] +xref: NIF_Subcellular:sao1153182838 +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0031982 ! vesicle + +[Term] +id: GO:0012507 +name: ER to Golgi transport vesicle membrane +namespace: cellular_component +alt_id: GO:0030664 +def: "The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi." [GOC:ai, GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "COPII coated vesicle membrane" EXACT [] +synonym: "endoplasmic reticulum to Golgi transport vesicle membrane" EXACT [] +synonym: "endoplasmic reticulum-Golgi transport vesicle membrane" EXACT [] +synonym: "ER to Golgi constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "ER-Golgi transport vesicle membrane" EXACT [] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030660 ! Golgi-associated vesicle membrane +is_a: GO:0030662 ! coated vesicle membrane +relationship: part_of GO:0030134 ! COPII-coated ER to Golgi transport vesicle + +[Term] +id: GO:0012508 +name: Golgi to ER transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER." [GOC:ai] +synonym: "Golgi to endoplasmic reticulum transport vesicle membrane" EXACT [] +synonym: "Golgi to ER constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "Golgi-endoplasmic reticulum transport vesicle membrane" EXACT [] +synonym: "Golgi-ER transport vesicle membrane" EXACT [] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030663 ! COPI-coated vesicle membrane +relationship: part_of GO:0030142 ! COPI-coated Golgi to ER transport vesicle + +[Term] +id: GO:0012509 +name: inter-Golgi transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vesicle transporting substances within the Golgi." [GOC:ai] +synonym: "inter-Golgi transport constitutive secretory pathway transport vesicle membrane" EXACT [] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030663 ! COPI-coated vesicle membrane +relationship: part_of GO:0030143 ! COPI-coated inter-Golgi transport vesicle + +[Term] +id: GO:0012510 +name: trans-Golgi network transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell." [GOC:ai] +synonym: "TGN transport vesicle membrane" EXACT [] +synonym: "trans-Golgi network constitutive secretory pathway transport vesicle membrane" EXACT [] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030660 ! Golgi-associated vesicle membrane +is_a: GO:0030665 ! clathrin-coated vesicle membrane +relationship: part_of GO:0030140 ! trans-Golgi network transport vesicle + +[Term] +id: GO:0012511 +name: monolayer-surrounded lipid storage body +namespace: cellular_component +alt_id: GO:0009520 +def: "A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins." [GOC:mtg_sensu, ISBN:0943088372] +synonym: "oil body" EXACT [] +synonym: "oilbody" EXACT [] +synonym: "oleosome" EXACT [] +synonym: "spherosome" EXACT [] +xref: Wikipedia:Oil_body +is_a: GO:0005811 ! lipid droplet + +[Term] +id: GO:0014001 +name: sclerenchyma cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable." [CL:0000276, GOC:ef, GOC:jid, PO:0000077] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0014002 +name: astrocyte development +namespace: biological_process +def: "The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." [GOC:dgh, GOC:ef] +synonym: "astrocyte cell development" EXACT [] +is_a: GO:0021782 ! glial cell development +relationship: part_of GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0014003 +name: oligodendrocyte development +namespace: biological_process +def: "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system." [GOC:dgh, GOC:ef] +synonym: "oligodendrocyte cell development" EXACT [] +is_a: GO:0021782 ! glial cell development +relationship: part_of GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0014004 +name: microglia differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system." [GOC:ef] +synonym: "microglial cell differentiation" EXACT [] +is_a: GO:0010001 ! glial cell differentiation +is_a: GO:0030225 ! macrophage differentiation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0014005 +name: microglia development +namespace: biological_process +def: "The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dgh, GOC:ef] +synonym: "microglial cell development" EXACT [] +is_a: GO:0021782 ! glial cell development +is_a: GO:0061515 ! myeloid cell development +relationship: part_of GO:0014004 ! microglia differentiation + +[Term] +id: GO:0014006 +name: regulation of microglia differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] +synonym: "regulation of microglial cell differentiation" EXACT [] +is_a: GO:0045649 ! regulation of macrophage differentiation +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014004 ! microglia differentiation +relationship: regulates GO:0014004 ! microglia differentiation + +[Term] +id: GO:0014007 +name: negative regulation of microglia differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] +synonym: "down regulation of microglia differentiation" EXACT [] +synonym: "down-regulation of microglia differentiation" EXACT [] +synonym: "downregulation of microglia differentiation" EXACT [] +synonym: "inhibition of microglia differentiation" NARROW [] +synonym: "negative regulation of microglial cell differentiation" EXACT [] +is_a: GO:0014006 ! regulation of microglia differentiation +is_a: GO:0045650 ! negative regulation of macrophage differentiation +is_a: GO:0045686 ! negative regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014004 ! microglia differentiation +relationship: negatively_regulates GO:0014004 ! microglia differentiation + +[Term] +id: GO:0014008 +name: positive regulation of microglia differentiation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] +synonym: "activation of microglia differentiation" NARROW [] +synonym: "positive regulation of microglial cell differentiation" EXACT [] +synonym: "stimulation of microglia differentiation" NARROW [] +synonym: "up regulation of microglia differentiation" EXACT [] +synonym: "up-regulation of microglia differentiation" EXACT [] +synonym: "upregulation of microglia differentiation" EXACT [] +is_a: GO:0014006 ! regulation of microglia differentiation +is_a: GO:0045651 ! positive regulation of macrophage differentiation +is_a: GO:0045687 ! positive regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014004 ! microglia differentiation +relationship: positively_regulates GO:0014004 ! microglia differentiation + +[Term] +id: GO:0014009 +name: glial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] +synonym: "glia proliferation" EXACT [] +is_a: GO:0008283 ! cell population proliferation +relationship: part_of GO:0042063 ! gliogenesis + +[Term] +id: GO:0014010 +name: Schwann cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:ef, ISBN:0878932585] +is_a: GO:0014009 ! glial cell proliferation + +[Term] +id: GO:0014011 +name: Schwann cell proliferation involved in axon regeneration +namespace: biological_process +def: "The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system." [GOC:ef, ISBN:0878932585] +is_a: GO:0014010 ! Schwann cell proliferation +intersection_of: GO:0014010 ! Schwann cell proliferation +intersection_of: part_of GO:0031103 ! axon regeneration +relationship: part_of GO:0014012 ! peripheral nervous system axon regeneration + +[Term] +id: GO:0014012 +name: peripheral nervous system axon regeneration +namespace: biological_process +def: "The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury." [GOC:ef] +synonym: "axon regeneration in peripheral nervous system" EXACT [] +is_a: GO:0031103 ! axon regeneration + +[Term] +id: GO:0014013 +name: regulation of gliogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] +is_a: GO:0050767 ! regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042063 ! gliogenesis +relationship: regulates GO:0042063 ! gliogenesis + +[Term] +id: GO:0014014 +name: negative regulation of gliogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] +synonym: "down regulation of gliogenesis" EXACT [] +synonym: "down-regulation of gliogenesis" EXACT [] +synonym: "downregulation of gliogenesis" EXACT [] +synonym: "inhibition of gliogenesis" NARROW [] +is_a: GO:0014013 ! regulation of gliogenesis +is_a: GO:0050768 ! negative regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042063 ! gliogenesis +relationship: negatively_regulates GO:0042063 ! gliogenesis + +[Term] +id: GO:0014015 +name: positive regulation of gliogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] +synonym: "activation of gliogenesis" NARROW [] +synonym: "stimulation of gliogenesis" NARROW [] +synonym: "up regulation of gliogenesis" EXACT [] +synonym: "up-regulation of gliogenesis" EXACT [] +synonym: "upregulation of gliogenesis" EXACT [] +is_a: GO:0014013 ! regulation of gliogenesis +is_a: GO:0050769 ! positive regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042063 ! gliogenesis +relationship: positively_regulates GO:0042063 ! gliogenesis + +[Term] +id: GO:0014016 +name: neuroblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585] +is_a: GO:0048863 ! stem cell differentiation +relationship: part_of GO:0048699 ! generation of neurons + +[Term] +id: GO:0014017 +name: neuroblast fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast." [GOC:ef, ISBN:0878932585] +is_a: GO:0048865 ! stem cell fate commitment +relationship: part_of GO:0014016 ! neuroblast differentiation + +[Term] +id: GO:0014018 +name: neuroblast fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GOC:ef, ISBN:0878932585] +is_a: GO:0048866 ! stem cell fate specification +relationship: part_of GO:0014017 ! neuroblast fate commitment + +[Term] +id: GO:0014019 +name: neuroblast development +namespace: biological_process +def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585] +is_a: GO:0048864 ! stem cell development +relationship: part_of GO:0014016 ! neuroblast differentiation + +[Term] +id: GO:0014020 +name: primary neural tube formation +namespace: biological_process +def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585] +synonym: "primary neural tube morphogenesis" EXACT [GOC:dph] +synonym: "primary neurulation" EXACT [] +is_a: GO:0001838 ! embryonic epithelial tube formation +relationship: part_of GO:0001841 ! neural tube formation + +[Term] +id: GO:0014021 +name: secondary neural tube formation +namespace: biological_process +alt_id: GO:0014026 +def: "The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals." [GOC:ef, ISBN:0878932585] +synonym: "medullary cord biosynthesis" EXACT [] +synonym: "medullary cord formation" EXACT [] +synonym: "neural rod formation" RELATED [] +synonym: "secondary neurulation" EXACT [] +is_a: GO:0001838 ! embryonic epithelial tube formation +relationship: part_of GO:0001841 ! neural tube formation + +[Term] +id: GO:0014022 +name: neural plate elongation +namespace: biological_process +def: "The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions." [GOC:ef, ISBN:0878932585] +is_a: GO:0002011 ! morphogenesis of an epithelial sheet +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001839 ! neural plate morphogenesis + +[Term] +id: GO:0014023 +name: neural rod formation +namespace: biological_process +def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0014020 ! primary neural tube formation + +[Term] +id: GO:0014024 +name: neural rod cavitation +namespace: biological_process +def: "The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube." [GOC:ef, PMID:15327780] +is_a: GO:0060605 ! tube lumen cavitation +relationship: part_of GO:0014020 ! primary neural tube formation + +[Term] +id: GO:0014025 +name: neural keel formation +namespace: biological_process +def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0014023 ! neural rod formation + +[Term] +id: GO:0014027 +name: secondary neural tube rod cavitation +namespace: biological_process +def: "The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube." [GOC:ef, PMID:15327780] +synonym: "medullary rod cavitation" EXACT [] +is_a: GO:0060605 ! tube lumen cavitation +relationship: part_of GO:0014021 ! secondary neural tube formation + +[Term] +id: GO:0014028 +name: notochord formation +namespace: biological_process +def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007399 ! nervous system development +relationship: part_of GO:0048570 ! notochord morphogenesis + +[Term] +id: GO:0014029 +name: neural crest formation +namespace: biological_process +def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef] +is_a: GO:0001837 ! epithelial to mesenchymal transition +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0014030 +name: mesenchymal cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become a mesenchymal cell." [GOC:dh, GOC:ef] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0048762 ! mesenchymal cell differentiation + +[Term] +id: GO:0014031 +name: mesenchymal cell development +namespace: biological_process +def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0048762 ! mesenchymal cell differentiation + +[Term] +id: GO:0014032 +name: neural crest cell development +namespace: biological_process +def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] +is_a: GO:0014031 ! mesenchymal cell development +is_a: GO:0048864 ! stem cell development +relationship: part_of GO:0014033 ! neural crest cell differentiation + +[Term] +id: GO:0014033 +name: neural crest cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef] +is_a: GO:0048762 ! mesenchymal cell differentiation +is_a: GO:0048863 ! stem cell differentiation + +[Term] +id: GO:0014034 +name: neural crest cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become a neural crest cell." [GOC:dh, GOC:ef] +is_a: GO:0048865 ! stem cell fate commitment +relationship: part_of GO:0014029 ! neural crest formation +relationship: part_of GO:0014033 ! neural crest cell differentiation + +[Term] +id: GO:0014035 +name: neural crest cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:dh, GOC:ef] +is_a: GO:0048867 ! stem cell fate determination +relationship: part_of GO:0014034 ! neural crest cell fate commitment + +[Term] +id: GO:0014036 +name: neural crest cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dh, GOC:ef] +is_a: GO:0048866 ! stem cell fate specification +relationship: part_of GO:0014034 ! neural crest cell fate commitment + +[Term] +id: GO:0014037 +name: Schwann cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:ef] +is_a: GO:0010001 ! glial cell differentiation +relationship: part_of GO:0007422 ! peripheral nervous system development + +[Term] +id: GO:0014038 +name: regulation of Schwann cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014037 ! Schwann cell differentiation +relationship: regulates GO:0014037 ! Schwann cell differentiation + +[Term] +id: GO:0014039 +name: negative regulation of Schwann cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] +synonym: "down regulation of Schwann cell differentiation" EXACT [] +synonym: "down-regulation of Schwann cell differentiation" EXACT [] +synonym: "downregulation of Schwann cell differentiation" EXACT [] +synonym: "inhibition of Schwann cell differentiation" NARROW [] +is_a: GO:0014038 ! regulation of Schwann cell differentiation +is_a: GO:0045686 ! negative regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014037 ! Schwann cell differentiation +relationship: negatively_regulates GO:0014037 ! Schwann cell differentiation + +[Term] +id: GO:0014040 +name: positive regulation of Schwann cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] +synonym: "activation of Schwann cell differentiation" NARROW [] +synonym: "stimulation of Schwann cell differentiation" NARROW [] +synonym: "up regulation of Schwann cell differentiation" EXACT [] +synonym: "up-regulation of Schwann cell differentiation" EXACT [] +synonym: "upregulation of Schwann cell differentiation" EXACT [] +is_a: GO:0014038 ! regulation of Schwann cell differentiation +is_a: GO:0045687 ! positive regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014037 ! Schwann cell differentiation +relationship: positively_regulates GO:0014037 ! Schwann cell differentiation + +[Term] +id: GO:0014041 +name: regulation of neuron maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:1903429 ! regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042551 ! neuron maturation +relationship: regulates GO:0042551 ! neuron maturation + +[Term] +id: GO:0014042 +name: positive regulation of neuron maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] +synonym: "activation of neuron maturation" NARROW [] +synonym: "stimulation of neuron maturation" NARROW [] +synonym: "up regulation of neuron maturation" EXACT [] +synonym: "up-regulation of neuron maturation" EXACT [] +synonym: "upregulation of neuron maturation" EXACT [] +is_a: GO:0014041 ! regulation of neuron maturation +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:1903431 ! positive regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042551 ! neuron maturation +relationship: positively_regulates GO:0042551 ! neuron maturation + +[Term] +id: GO:0014043 +name: negative regulation of neuron maturation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] +synonym: "down regulation of neuron maturation" EXACT [] +synonym: "down-regulation of neuron maturation" EXACT [] +synonym: "downregulation of neuron maturation" EXACT [] +synonym: "inhibition of neuron maturation" NARROW [] +is_a: GO:0014041 ! regulation of neuron maturation +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:1903430 ! negative regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042551 ! neuron maturation +relationship: negatively_regulates GO:0042551 ! neuron maturation + +[Term] +id: GO:0014044 +name: Schwann cell development +namespace: biological_process +def: "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:dgh, GOC:ef] +is_a: GO:0021782 ! glial cell development +relationship: part_of GO:0014037 ! Schwann cell differentiation + +[Term] +id: GO:0014045 +name: establishment of endothelial blood-brain barrier +namespace: biological_process +def: "Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:aruk, GOC:dgh, GOC:dph, GOC:sart, PMID:20080302, PMID:30280653] +synonym: "establishment of endothelial BBB" EXACT [] +synonym: "establishment of endothelial blood/brain barrier" EXACT [] +is_a: GO:0060856 ! establishment of blood-brain barrier +is_a: GO:0061028 ! establishment of endothelial barrier + +[Term] +id: GO:0014046 +name: dopamine secretion +namespace: biological_process +def: "The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone." [GOC:ef] +is_a: GO:0015872 ! dopamine transport +is_a: GO:0023061 ! signal release +is_a: GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0014047 +name: glutamate secretion +namespace: biological_process +def: "The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system." [GOC:ef] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0014048 +name: regulation of glutamate secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of glutamate." [GOC:ef] +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014047 ! glutamate secretion +relationship: regulates GO:0014047 ! glutamate secretion + +[Term] +id: GO:0014049 +name: positive regulation of glutamate secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate." [GOC:ef] +synonym: "activation of glutamate secretion" NARROW [] +synonym: "stimulation of glutamate secretion" NARROW [] +synonym: "up regulation of glutamate secretion" EXACT [] +synonym: "up-regulation of glutamate secretion" EXACT [] +synonym: "upregulation of glutamate secretion" EXACT [] +is_a: GO:0014048 ! regulation of glutamate secretion +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014047 ! glutamate secretion +relationship: positively_regulates GO:0014047 ! glutamate secretion + +[Term] +id: GO:0014050 +name: negative regulation of glutamate secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate." [GOC:ef] +synonym: "down regulation of glutamate secretion" EXACT [] +synonym: "down-regulation of glutamate secretion" EXACT [] +synonym: "downregulation of glutamate secretion" EXACT [] +synonym: "inhibition of glutamate secretion" NARROW [] +is_a: GO:0014048 ! regulation of glutamate secretion +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014047 ! glutamate secretion +relationship: negatively_regulates GO:0014047 ! glutamate secretion + +[Term] +id: GO:0014051 +name: gamma-aminobutyric acid secretion +namespace: biological_process +def: "The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues." [GOC:ef] +synonym: "GABA secretion" EXACT [] +is_a: GO:0015812 ! gamma-aminobutyric acid transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0014052 +name: regulation of gamma-aminobutyric acid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] +synonym: "regulation of GABA secretion" EXACT [] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:0051955 ! regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014051 ! gamma-aminobutyric acid secretion +relationship: regulates GO:0014051 ! gamma-aminobutyric acid secretion + +[Term] +id: GO:0014053 +name: negative regulation of gamma-aminobutyric acid secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] +synonym: "down regulation of gamma-aminobutyric acid secretion" EXACT [] +synonym: "down-regulation of gamma-aminobutyric acid secretion" EXACT [] +synonym: "downregulation of gamma-aminobutyric acid secretion" EXACT [] +synonym: "inhibition of gamma-aminobutyric acid secretion" NARROW [] +synonym: "negative regulation of GABA secretion" EXACT [] +is_a: GO:0014052 ! regulation of gamma-aminobutyric acid secretion +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:0051956 ! negative regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014051 ! gamma-aminobutyric acid secretion +relationship: negatively_regulates GO:0014051 ! gamma-aminobutyric acid secretion + +[Term] +id: GO:0014054 +name: positive regulation of gamma-aminobutyric acid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] +synonym: "activation of gamma-aminobutyric acid secretion" NARROW [] +synonym: "positive regulation of GABA secretion" EXACT [] +synonym: "stimulation of gamma-aminobutyric acid secretion" NARROW [] +synonym: "up regulation of gamma-aminobutyric acid secretion" EXACT [] +synonym: "up-regulation of gamma-aminobutyric acid secretion" EXACT [] +synonym: "upregulation of gamma-aminobutyric acid secretion" EXACT [] +is_a: GO:0014052 ! regulation of gamma-aminobutyric acid secretion +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:0051957 ! positive regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014051 ! gamma-aminobutyric acid secretion +relationship: positively_regulates GO:0014051 ! gamma-aminobutyric acid secretion + +[Term] +id: GO:0014055 +name: acetylcholine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0061526 ! acetylcholine secretion +intersection_of: GO:0061526 ! acetylcholine secretion +intersection_of: part_of GO:0007271 ! synaptic transmission, cholinergic +relationship: part_of GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0014056 +name: regulation of acetylcholine secretion, neurotransmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] +is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0051952 ! regulation of amine transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014055 ! acetylcholine secretion, neurotransmission +relationship: regulates GO:0014055 ! acetylcholine secretion, neurotransmission + +[Term] +id: GO:0014057 +name: positive regulation of acetylcholine secretion, neurotransmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] +synonym: "activation of acetylcholine secretion" NARROW [] +synonym: "stimulation of acetylcholine secretion" NARROW [] +synonym: "up regulation of acetylcholine secretion" EXACT [] +synonym: "up-regulation of acetylcholine secretion" EXACT [] +synonym: "upregulation of acetylcholine secretion" EXACT [] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission +is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051954 ! positive regulation of amine transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission +relationship: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission + +[Term] +id: GO:0014058 +name: negative regulation of acetylcholine secretion, neurotransmission +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] +synonym: "down regulation of acetylcholine secretion" EXACT [] +synonym: "down-regulation of acetylcholine secretion" EXACT [] +synonym: "downregulation of acetylcholine secretion" EXACT [] +synonym: "inhibition of acetylcholine secretion" NARROW [] +is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission +is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:0051953 ! negative regulation of amine transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission +relationship: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission + +[Term] +id: GO:0014059 +name: regulation of dopamine secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of dopamine." [GOC:ef] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0050433 ! regulation of catecholamine secretion +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014046 ! dopamine secretion +relationship: regulates GO:0014046 ! dopamine secretion + +[Term] +id: GO:0014060 +name: regulation of epinephrine secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of epinephrine." [GOC:ef] +synonym: "regulation of adrenaline secretion" EXACT [] +is_a: GO:0050433 ! regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048242 ! epinephrine secretion +relationship: regulates GO:0048242 ! epinephrine secretion + +[Term] +id: GO:0014061 +name: regulation of norepinephrine secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] +synonym: "regulation of noradrenaline secretion" EXACT [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0050433 ! regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048243 ! norepinephrine secretion +relationship: regulates GO:0048243 ! norepinephrine secretion + +[Term] +id: GO:0014062 +name: regulation of serotonin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] +synonym: "regulation of serotonin release" RELATED [GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001820 ! serotonin secretion +relationship: regulates GO:0001820 ! serotonin secretion + +[Term] +id: GO:0014063 +name: negative regulation of serotonin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] +synonym: "down regulation of serotonin secretion" EXACT [] +synonym: "down-regulation of serotonin secretion" EXACT [] +synonym: "downregulation of serotonin secretion" EXACT [] +synonym: "inhibition of serotonin secretion" NARROW [] +synonym: "positive regulation of serotonin release" RELATED [GOC:tb] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0014062 ! regulation of serotonin secretion +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001820 ! serotonin secretion +relationship: negatively_regulates GO:0001820 ! serotonin secretion + +[Term] +id: GO:0014064 +name: positive regulation of serotonin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] +synonym: "activation of serotonin secretion" NARROW [] +synonym: "positive regulation of serotonin release" RELATED [GOC:tb] +synonym: "stimulation of serotonin secretion" NARROW [] +synonym: "up regulation of serotonin secretion" EXACT [] +synonym: "up-regulation of serotonin secretion" EXACT [] +synonym: "upregulation of serotonin secretion" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0014062 ! regulation of serotonin secretion +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001820 ! serotonin secretion +relationship: positively_regulates GO:0001820 ! serotonin secretion + +[Term] +id: GO:0014065 +name: phosphatidylinositol 3-kinase signaling +namespace: biological_process +def: "A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions." [GOC:ef, http://www.biocarta.com, PMID:22525052, Wikipedia:PI3K] +synonym: "phosphatidylinositol 3-kinase cascade" RELATED [GOC:signaling] +synonym: "phosphatidylinositol 3-kinase signal transduction" EXACT [GOC:signaling] +synonym: "phosphoinositide 3-kinase cascade" EXACT [] +synonym: "PI 3-kinase cascade" EXACT [] +synonym: "PI3K cascade" EXACT [] +synonym: "PI3K signal transduction" EXACT [GOC:signaling] +synonym: "PI3K signaling" EXACT [GOC:signaling] +is_a: GO:0048015 ! phosphatidylinositol-mediated signaling + +[Term] +id: GO:0014066 +name: regulation of phosphatidylinositol 3-kinase signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade." [GOC:ef] +synonym: "regulation of phosphatidylinositol 3-kinase cascade" RELATED [] +synonym: "regulation of phosphoinositide 3-kinase cascade" EXACT [] +synonym: "regulation of PI 3-kinase cascade" RELATED [] +synonym: "regulation of PI3K cascade" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling +relationship: regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling + +[Term] +id: GO:0014067 +name: negative regulation of phosphatidylinositol 3-kinase signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade." [GOC:ef] +synonym: "down regulation of phosphatidylinositol 3-kinase cascade" EXACT [] +synonym: "down-regulation of phosphatidylinositol 3-kinase cascade" EXACT [] +synonym: "downregulation of phosphatidylinositol 3-kinase cascade" EXACT [] +synonym: "inhibition of phosphatidylinositol 3-kinase cascade" NARROW [] +synonym: "negative regulation of phosphatidylinositol 3-kinase cascade" RELATED [] +synonym: "negative regulation of phosphoinositide 3-kinase cascade" EXACT [] +synonym: "negative regulation of PI 3-kinase cascade" EXACT [] +synonym: "negative regulation of PI3K cascade" EXACT [] +is_a: GO:0014066 ! regulation of phosphatidylinositol 3-kinase signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling +relationship: negatively_regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling + +[Term] +id: GO:0014068 +name: positive regulation of phosphatidylinositol 3-kinase signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade." [GOC:ef] +synonym: "activation of phosphoinositide 3-kinase cascade" NARROW [] +synonym: "positive regulation of phosphatidylinositol 3-kinase cascade" RELATED [] +synonym: "positive regulation of phosphoinositide 3-kinase cascade" EXACT [] +synonym: "positive regulation of PI 3-kinase cascade" EXACT [] +synonym: "positive regulation of PI3K cascade" EXACT [] +synonym: "stimulation of phosphatidylinositol 3-kinase cascade" NARROW [] +synonym: "up regulation of phosphatidylinositol 3-kinase cascade" EXACT [] +synonym: "up-regulation of phosphatidylinositol 3-kinase cascade" EXACT [] +synonym: "upregulation of phosphatidylinositol 3-kinase cascade" EXACT [] +is_a: GO:0014066 ! regulation of phosphatidylinositol 3-kinase signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling +relationship: positively_regulates GO:0014065 ! phosphatidylinositol 3-kinase signaling + +[Term] +id: GO:0014069 +name: postsynaptic density +namespace: cellular_component +alt_id: GO:0097481 +alt_id: GO:0097483 +def: "An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components." [GOC:BHF, GOC:dos, GOC:ef, GOC:jid, GOC:pr, GOC:sjp, http://molneuro.kaist.ac.kr/psd, PMID:14532281, Wikipedia:Postsynaptic_density] +subset: goslim_synapse +synonym: "neuronal postsynaptic density" EXACT [GO:0097481] +synonym: "post synaptic density" EXACT [] +synonym: "post-synaptic density" EXACT [] +synonym: "postsynaptic density of dendrite" NARROW [] +xref: NIF_Subcellular:sao1196688972 +xref: Wikipedia:Postsynaptic_density +is_a: GO:0099572 ! postsynaptic specialization +intersection_of: GO:0099572 ! postsynaptic specialization +intersection_of: part_of GO:0032279 ! asymmetric synapse +relationship: part_of GO:0032279 ! asymmetric synapse +created_by: pr +creation_date: 2013-07-02T09:44:28Z + +[Term] +id: GO:0014070 +name: response to organic cyclic compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef] +synonym: "response to organic cyclic substance" EXACT [GOC:mah] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0014071 +name: response to cycloalkane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n." [GOC:ef] +is_a: GO:0014070 ! response to organic cyclic compound + +[Term] +id: GO:0014072 +name: response to isoquinoline alkaloid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids." [GOC:ef] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043279 ! response to alkaloid + +[Term] +id: GO:0014073 +name: response to tropane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine." [GOC:ef] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043279 ! response to alkaloid + +[Term] +id: GO:0014074 +name: response to purine-containing compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus." [GOC:ef] +synonym: "response to purine" RELATED [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound + +[Term] +id: GO:0014075 +name: response to amine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] +synonym: "response to amine stimulus" EXACT [GOC:dos] +is_a: GO:0010243 ! response to organonitrogen compound + +[Term] +id: GO:0014076 +name: response to fluoxetine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor." [GOC:ef, GOC:pr] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to selective serotonin reuptake inhibitor" RELATED [] +synonym: "response to SSRI" RELATED [] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0036276 ! response to antidepressant + +[Term] +id: GO:0014701 +name: junctional sarcoplasmic reticulum membrane +namespace: cellular_component +def: "The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane." [GOC:mtg_muscle] +is_a: GO:0033017 ! sarcoplasmic reticulum membrane + +[Term] +id: GO:0014702 +name: free sarcoplasmic reticulum membrane +namespace: cellular_component +def: "The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane." [GOC:mtg_muscle] +is_a: GO:0033017 ! sarcoplasmic reticulum membrane + +[Term] +id: GO:0014703 +name: oscillatory muscle contraction +namespace: biological_process +def: "A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation." [GOC:mtg_muscle] +is_a: GO:0003010 ! voluntary skeletal muscle contraction + +[Term] +id: GO:0014704 +name: intercalated disc +namespace: cellular_component +def: "A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells." [GOC:mtg_muscle, PMID:11732910] +synonym: "intercalated disk" EXACT [] +xref: Wikipedia:Intercalated_disc +is_a: GO:0044291 ! cell-cell contact zone + +[Term] +id: GO:0014705 +name: C zone +namespace: cellular_component +def: "A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin." [GOC:mtg_muscle] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031672 ! A band + +[Term] +id: GO:0014706 +name: striated muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle] +is_a: GO:0060537 ! muscle tissue development + +[Term] +id: GO:0014707 +name: branchiomeric skeletal muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish." [GOC:mtg_muscle] +is_a: GO:0007517 ! muscle organ development +is_a: GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0014708 +name: regulation of somitomeric trunk muscle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development." [GOC:mtg_muscle] +is_a: GO:0048634 ! regulation of muscle organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002075 ! somitomeric trunk muscle development +relationship: regulates GO:0002075 ! somitomeric trunk muscle development + +[Term] +id: GO:0014709 +name: positive regulation of somitomeric trunk muscle development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle." [GOC:mtg_muscle] +is_a: GO:0014708 ! regulation of somitomeric trunk muscle development +is_a: GO:0048636 ! positive regulation of muscle organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002075 ! somitomeric trunk muscle development +relationship: positively_regulates GO:0002075 ! somitomeric trunk muscle development + +[Term] +id: GO:0014710 +name: negative regulation of somitomeric trunk muscle development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle." [GOC:mtg_muscle] +is_a: GO:0014708 ! regulation of somitomeric trunk muscle development +is_a: GO:0048635 ! negative regulation of muscle organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002075 ! somitomeric trunk muscle development +relationship: negatively_regulates GO:0002075 ! somitomeric trunk muscle development + +[Term] +id: GO:0014711 +name: regulation of branchiomeric skeletal muscle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure." [GOC:mtg_muscle] +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014707 ! branchiomeric skeletal muscle development +relationship: regulates GO:0014707 ! branchiomeric skeletal muscle development + +[Term] +id: GO:0014712 +name: positive regulation of branchiomeric skeletal muscle development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure." [GOC:mtg_muscle] +is_a: GO:0014711 ! regulation of branchiomeric skeletal muscle development +is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014707 ! branchiomeric skeletal muscle development +relationship: positively_regulates GO:0014707 ! branchiomeric skeletal muscle development + +[Term] +id: GO:0014713 +name: negative regulation of branchiomeric skeletal muscle development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure." [GOC:mtg_muscle] +is_a: GO:0014711 ! regulation of branchiomeric skeletal muscle development +is_a: GO:0048642 ! negative regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014707 ! branchiomeric skeletal muscle development +relationship: negatively_regulates GO:0014707 ! branchiomeric skeletal muscle development + +[Term] +id: GO:0014714 +name: myoblast fate commitment in head +namespace: biological_process +def: "The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle] +is_a: GO:0048625 ! myoblast fate commitment + +[Term] +id: GO:0014715 +name: myoblast fate commitment in trunk +namespace: biological_process +def: "The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle] +is_a: GO:0048625 ! myoblast fate commitment + +[Term] +id: GO:0014716 +name: skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration +namespace: biological_process +def: "Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt." [GOC:mtg_muscle] +comment: Occurrence of this process outside of the context of muscle repair is probably very rare, so there is a good case for merging this with the parent class. +synonym: "satellite cell asymmetric division involved in skeletal muscle regeneration" EXACT [] +is_a: GO:0014833 ! skeletal muscle satellite stem cell asymmetric division +intersection_of: GO:0014833 ! skeletal muscle satellite stem cell asymmetric division +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014834 ! skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration + +[Term] +id: GO:0014717 +name: regulation of satellite cell activation involved in skeletal muscle regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate." [GOC:mtg_muscle] +is_a: GO:0043416 ! regulation of skeletal muscle tissue regeneration +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration +relationship: regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration + +[Term] +id: GO:0014718 +name: positive regulation of satellite cell activation involved in skeletal muscle regeneration +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate." [GOC:mtg_muscle] +is_a: GO:0014717 ! regulation of satellite cell activation involved in skeletal muscle regeneration +is_a: GO:0043415 ! positive regulation of skeletal muscle tissue regeneration +is_a: GO:0050867 ! positive regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration +relationship: positively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration + +[Term] +id: GO:0014719 +name: skeletal muscle satellite cell activation +namespace: biological_process +def: "The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:mtg_muscle, PMID:23303905] +is_a: GO:0001775 ! cell activation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0014720 +name: tonic skeletal muscle contraction +namespace: biological_process +def: "A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue." [GOC:mtg_muscle] +is_a: GO:0003010 ! voluntary skeletal muscle contraction + +[Term] +id: GO:0014721 +name: twitch skeletal muscle contraction +namespace: biological_process +def: "A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation." [GOC:mtg_muscle] +is_a: GO:0003010 ! voluntary skeletal muscle contraction + +[Term] +id: GO:0014722 +name: regulation of skeletal muscle contraction by calcium ion signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction." [GOC:mtg_muscle] +synonym: "regulation of skeletal muscle contraction by calcium ion signalling" EXACT [] +is_a: GO:0014819 ! regulation of skeletal muscle contraction +is_a: GO:0019722 ! calcium-mediated signaling +intersection_of: GO:0019722 ! calcium-mediated signaling +intersection_of: regulates GO:0003009 ! skeletal muscle contraction + +[Term] +id: GO:0014723 +name: regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril." [GOC:mtg_muscle] +synonym: "regulation of calcium ion sensitivity of myofibril involved in skeletal muscle contraction" EXACT [] +is_a: GO:0014722 ! regulation of skeletal muscle contraction by calcium ion signaling + +[Term] +id: GO:0014724 +name: regulation of twitch skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction." [GOC:mtg_muscle] +is_a: GO:0014819 ! regulation of skeletal muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014721 ! twitch skeletal muscle contraction +relationship: regulates GO:0014721 ! twitch skeletal muscle contraction + +[Term] +id: GO:0014725 +name: regulation of extraocular skeletal muscle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle." [GOC:mtg_muscle] +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002074 ! extraocular skeletal muscle development +relationship: regulates GO:0002074 ! extraocular skeletal muscle development + +[Term] +id: GO:0014726 +name: negative regulation of extraocular skeletal muscle development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle." [GOC:mtg_muscle] +is_a: GO:0014725 ! regulation of extraocular skeletal muscle development +is_a: GO:0048642 ! negative regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002074 ! extraocular skeletal muscle development +relationship: negatively_regulates GO:0002074 ! extraocular skeletal muscle development + +[Term] +id: GO:0014727 +name: positive regulation of extraocular skeletal muscle development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle." [GOC:mtg_muscle] +is_a: GO:0014725 ! regulation of extraocular skeletal muscle development +is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002074 ! extraocular skeletal muscle development +relationship: positively_regulates GO:0002074 ! extraocular skeletal muscle development + +[Term] +id: GO:0014728 +name: regulation of the force of skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges." [GOC:mtg_muscle] +is_a: GO:0014862 ! regulation of skeletal muscle contraction by chemo-mechanical energy conversion + +[Term] +id: GO:0014729 +name: regulation of the velocity of shortening of skeletal muscle modulating contraction +namespace: biological_process +def: "Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres." [GOC:mtg_muscle] +synonym: "regulation of the velocity of shortening of skeletal muscle during contraction" RELATED [GOC:dph] +is_a: GO:0014862 ! regulation of skeletal muscle contraction by chemo-mechanical energy conversion +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0014730 +name: skeletal muscle regeneration at neuromuscular junction +namespace: biological_process +def: "The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers." [GOC:mtg_muscle] +is_a: GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014731 +name: spectrin-associated cytoskeleton +namespace: cellular_component +def: "The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane." [GOC:mtg_muscle, PMID:15970557] +is_a: GO:0005856 ! cytoskeleton + +[Term] +id: GO:0014732 +name: skeletal muscle atrophy +namespace: biological_process +def: "A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse." [GOC:mtg_muscle] +is_a: GO:0014891 ! striated muscle atrophy +is_a: GO:0043501 ! skeletal muscle adaptation + +[Term] +id: GO:0014733 +name: regulation of skeletal muscle adaptation +namespace: biological_process +def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] +synonym: "regulation of skeletal muscle plasticity" RELATED [] +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043501 ! skeletal muscle adaptation +relationship: regulates GO:0043501 ! skeletal muscle adaptation + +[Term] +id: GO:0014734 +name: skeletal muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] +is_a: GO:0014897 ! striated muscle hypertrophy +is_a: GO:0043501 ! skeletal muscle adaptation + +[Term] +id: GO:0014735 +name: regulation of muscle atrophy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle atrophy." [GOC:mtg_muscle] +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014889 ! muscle atrophy +relationship: regulates GO:0014889 ! muscle atrophy + +[Term] +id: GO:0014736 +name: negative regulation of muscle atrophy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy." [GOC:mtg_muscle] +is_a: GO:0014735 ! regulation of muscle atrophy +is_a: GO:0014745 ! negative regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014889 ! muscle atrophy +relationship: negatively_regulates GO:0014889 ! muscle atrophy + +[Term] +id: GO:0014737 +name: positive regulation of muscle atrophy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle atrophy." [GOC:mtg_muscle] +is_a: GO:0014735 ! regulation of muscle atrophy +is_a: GO:0014744 ! positive regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014889 ! muscle atrophy +relationship: positively_regulates GO:0014889 ! muscle atrophy + +[Term] +id: GO:0014738 +name: regulation of muscle hyperplasia +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle hyperplasia." [GOC:mtg_muscle] +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014900 ! muscle hyperplasia +relationship: regulates GO:0014900 ! muscle hyperplasia + +[Term] +id: GO:0014739 +name: positive regulation of muscle hyperplasia +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle hyperplasia." [GOC:mtg_muscle] +is_a: GO:0014738 ! regulation of muscle hyperplasia +is_a: GO:0014744 ! positive regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014900 ! muscle hyperplasia +relationship: positively_regulates GO:0014900 ! muscle hyperplasia + +[Term] +id: GO:0014740 +name: negative regulation of muscle hyperplasia +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia." [GOC:mtg_muscle] +is_a: GO:0014738 ! regulation of muscle hyperplasia +is_a: GO:0014745 ! negative regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014900 ! muscle hyperplasia +relationship: negatively_regulates GO:0014900 ! muscle hyperplasia + +[Term] +id: GO:0014741 +name: negative regulation of muscle hypertrophy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle] +is_a: GO:0014743 ! regulation of muscle hypertrophy +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014896 ! muscle hypertrophy +relationship: negatively_regulates GO:0014896 ! muscle hypertrophy + +[Term] +id: GO:0014742 +name: positive regulation of muscle hypertrophy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] +is_a: GO:0014743 ! regulation of muscle hypertrophy +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014896 ! muscle hypertrophy +relationship: positively_regulates GO:0014896 ! muscle hypertrophy + +[Term] +id: GO:0014743 +name: regulation of muscle hypertrophy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] +is_a: GO:0090257 ! regulation of muscle system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014896 ! muscle hypertrophy +relationship: regulates GO:0014896 ! muscle hypertrophy + +[Term] +id: GO:0014744 +name: positive regulation of muscle adaptation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle] +synonym: "positive regulation of muscle plasticity" RELATED [] +is_a: GO:0043502 ! regulation of muscle adaptation +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043500 ! muscle adaptation +relationship: positively_regulates GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014745 +name: negative regulation of muscle adaptation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle] +synonym: "negative regulation of muscle plasticity" RELATED [] +is_a: GO:0043502 ! regulation of muscle adaptation +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043500 ! muscle adaptation +relationship: negatively_regulates GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014746 +name: regulation of tonic skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction." [GOC:mtg_muscle] +is_a: GO:0014819 ! regulation of skeletal muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014720 ! tonic skeletal muscle contraction +relationship: regulates GO:0014720 ! tonic skeletal muscle contraction + +[Term] +id: GO:0014747 +name: positive regulation of tonic skeletal muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014746 ! regulation of tonic skeletal muscle contraction +is_a: GO:0045989 ! positive regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014720 ! tonic skeletal muscle contraction +relationship: positively_regulates GO:0014720 ! tonic skeletal muscle contraction + +[Term] +id: GO:0014748 +name: negative regulation of tonic skeletal muscle contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014746 ! regulation of tonic skeletal muscle contraction +is_a: GO:0045988 ! negative regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014720 ! tonic skeletal muscle contraction +relationship: negatively_regulates GO:0014720 ! tonic skeletal muscle contraction + +[Term] +id: GO:0014801 +name: longitudinal sarcoplasmic reticulum +namespace: cellular_component +def: "The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae." [GOC:mtg_muscle] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016529 ! sarcoplasmic reticulum + +[Term] +id: GO:0014802 +name: terminal cisterna +namespace: cellular_component +def: "The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release." [GOC:mtg_muscle] +xref: Wikipedia:Terminal_cisterna +is_a: GO:0098827 ! endoplasmic reticulum subcompartment +relationship: part_of GO:0016529 ! sarcoplasmic reticulum + +[Term] +id: GO:0014803 +name: longitudinal sarcoplasmic reticulum lumen +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae." [GOC:mtg_muscle] +is_a: GO:0033018 ! sarcoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0014801 ! longitudinal sarcoplasmic reticulum +relationship: part_of GO:0014801 ! longitudinal sarcoplasmic reticulum + +[Term] +id: GO:0014804 +name: terminal cisterna lumen +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin." [GOC:mtg_muscle] +is_a: GO:0033018 ! sarcoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0014802 ! terminal cisterna +relationship: part_of GO:0014802 ! terminal cisterna + +[Term] +id: GO:0014805 +name: smooth muscle adaptation +namespace: biological_process +def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] +synonym: "smooth muscle plasticity" RELATED [] +is_a: GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014806 +name: smooth muscle hyperplasia +namespace: biological_process +def: "A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ." [GOC:mtg_muscle] +is_a: GO:0014805 ! smooth muscle adaptation +is_a: GO:0014900 ! muscle hyperplasia + +[Term] +id: GO:0014807 +name: regulation of somitogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001756 ! somitogenesis +relationship: regulates GO:0001756 ! somitogenesis + +[Term] +id: GO:0014808 +name: release of sequestered calcium ion into cytosol by sarcoplasmic reticulum +namespace: biological_process +def: "The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels." [GOC:mtg_muscle] +synonym: "release of sequestered calcium ion by sarcoplasmic reticulum into cytosol" RELATED [GOC:dph, GOC:tb] +is_a: GO:0070296 ! sarcoplasmic reticulum calcium ion transport +is_a: GO:1903514 ! release of sequestered calcium ion into cytosol by endoplasmic reticulum + +[Term] +id: GO:0014809 +name: regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction." [GOC:mtg_muscle] +is_a: GO:0010880 ! regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum +is_a: GO:0014722 ! regulation of skeletal muscle contraction by calcium ion signaling + +[Term] +id: GO:0014810 +name: positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction." [GOC:mtg_muscle] +is_a: GO:0014809 ! regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion +is_a: GO:0045989 ! positive regulation of striated muscle contraction + +[Term] +id: GO:0014811 +name: negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction." [GOC:mtg_muscle] +is_a: GO:0014809 ! regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion +is_a: GO:0045988 ! negative regulation of striated muscle contraction + +[Term] +id: GO:0014812 +name: muscle cell migration +namespace: biological_process +def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle] +is_a: GO:0016477 ! cell migration + +[Term] +id: GO:0014813 +name: skeletal muscle satellite cell commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0014816 ! skeletal muscle satellite cell differentiation + +[Term] +id: GO:0014814 +name: axon regeneration at neuromuscular junction +namespace: biological_process +def: "The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0031103 ! axon regeneration + +[Term] +id: GO:0014815 +name: initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration +namespace: biological_process +def: "Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0014718 ! positive regulation of satellite cell activation involved in skeletal muscle regeneration + +[Term] +id: GO:0014816 +name: skeletal muscle satellite cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a satellite cell." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0035914 ! skeletal muscle cell differentiation + +[Term] +id: GO:0014817 +name: skeletal muscle satellite cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0014813 ! skeletal muscle satellite cell commitment + +[Term] +id: GO:0014818 +name: skeletal muscle satellite cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0048867 ! stem cell fate determination +relationship: part_of GO:0014813 ! skeletal muscle satellite cell commitment + +[Term] +id: GO:0014819 +name: regulation of skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0006942 ! regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003009 ! skeletal muscle contraction +relationship: regulates GO:0003009 ! skeletal muscle contraction + +[Term] +id: GO:0014820 +name: tonic smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction." [GOC:mtg_muscle] +is_a: GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0014821 +name: phasic smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle] +is_a: GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0014822 +name: detection of wounding +namespace: biological_process +def: "The series of events by which an injury stimulus is received and converted into a molecular signal." [GOC:mtg_muscle] +synonym: "detection of injury" EXACT [] +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009611 ! response to wounding + +[Term] +id: GO:0014823 +name: response to activity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus." [GOC:mtg_muscle] +synonym: "response to exercise" RELATED [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0014824 +name: artery smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart." [GOC:mtg_muscle, MA:0000708, MSH:D001158] +is_a: GO:0014820 ! tonic smooth muscle contraction +is_a: GO:0014829 ! vascular smooth muscle contraction + +[Term] +id: GO:0014825 +name: stomach fundus smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch." [GOC:mtg_muscle, MA:0001612] +is_a: GO:0014847 ! proximal stomach smooth muscle contraction + +[Term] +id: GO:0014826 +name: vein smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds." [GOC:mtg_muscle, MA:0000715, MSH:D014680] +is_a: GO:0014821 ! phasic smooth muscle contraction +is_a: GO:0014829 ! vascular smooth muscle contraction + +[Term] +id: GO:0014827 +name: intestine smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422] +is_a: GO:0014821 ! phasic smooth muscle contraction +is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction + +[Term] +id: GO:0014828 +name: distal stomach smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus." [GOC:mtg_muscle, PMID:30252381] +is_a: GO:0014821 ! phasic smooth muscle contraction +is_a: GO:0120063 ! stomach smooth muscle contraction + +[Term] +id: GO:0014829 +name: vascular smooth muscle contraction +namespace: biological_process +def: "A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion." [GOC:mtg_muscle, MA:0002718] +is_a: GO:0006939 ! smooth muscle contraction +is_a: GO:0042310 ! vasoconstriction + +[Term] +id: GO:0014830 +name: arteriole smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries." [GOC:mtg_muscle, MA:0000706, MSH:D001160] +is_a: GO:0014824 ! artery smooth muscle contraction + +[Term] +id: GO:0014831 +name: gastro-intestinal system smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981] +is_a: GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0014832 +name: urinary bladder smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956] +is_a: GO:0014848 ! urinary tract smooth muscle contraction +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0014833 +name: skeletal muscle satellite stem cell asymmetric division +namespace: biological_process +def: "The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +synonym: "satellite cell asymmetric division" EXACT [] +is_a: GO:0048103 ! somatic stem cell division +is_a: GO:0098722 ! asymmetric stem cell division +relationship: part_of GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0014834 +name: skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration +namespace: biological_process +def: "Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells." [GOC:dph, GOC:ef, GOC:mtg_muscle, GOC:tb, PMID:23303905] +synonym: "satellite cell compartment self-renewal involved in skeletal muscle regeneration" EXACT [GOC:dph, GOC:tb] +synonym: "satellite cell population maintenance" EXACT [] +synonym: "satellite cell self-renewal" BROAD [] +is_a: GO:0098727 ! maintenance of cell number +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014835 +name: myoblast differentiation involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0045445 ! myoblast differentiation +intersection_of: GO:0045445 ! myoblast differentiation +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014836 +name: myoblast fate commitment involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0048625 ! myoblast fate commitment +intersection_of: GO:0048625 ! myoblast fate commitment +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014835 ! myoblast differentiation involved in skeletal muscle regeneration + +[Term] +id: GO:0014837 +name: myoblast fate determination involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0007518 ! myoblast fate determination +intersection_of: GO:0007518 ! myoblast fate determination +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014836 ! myoblast fate commitment involved in skeletal muscle regeneration + +[Term] +id: GO:0014838 +name: myoblast fate specification involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0048626 ! myoblast fate specification +intersection_of: GO:0048626 ! myoblast fate specification +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014836 ! myoblast fate commitment involved in skeletal muscle regeneration + +[Term] +id: GO:0014839 +name: myoblast migration involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +synonym: "mononucleate cell migration involved in skeletal muscle regeneration" BROAD [] +is_a: GO:0051451 ! myoblast migration +intersection_of: GO:0051451 ! myoblast migration +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014841 +name: skeletal muscle satellite cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0014856 ! skeletal muscle cell proliferation + +[Term] +id: GO:0014842 +name: regulation of skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014841 ! skeletal muscle satellite cell proliferation +relationship: regulates GO:0014841 ! skeletal muscle satellite cell proliferation + +[Term] +id: GO:0014843 +name: growth factor dependent regulation of skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta." [GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0014842 ! regulation of skeletal muscle satellite cell proliferation + +[Term] +id: GO:0014844 +name: myoblast proliferation involved in skeletal muscle regeneration +namespace: biological_process +def: "The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] +is_a: GO:0051450 ! myoblast proliferation +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014845 +name: stomach body smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined." [GOC:ef, GOC:mtg_muscle, MA:0002559] +is_a: GO:0014828 ! distal stomach smooth muscle contraction + +[Term] +id: GO:0014846 +name: esophagus smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract." [GOC:ef, GOC:mtg_muscle, MA:0001573, MSH:D041742] +synonym: "oesophagus smooth muscle contraction" RELATED [GOC:dph] +is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction + +[Term] +id: GO:0014847 +name: proximal stomach smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach." [GOC:mtg_muscle, PMID:30252381] +is_a: GO:0014820 ! tonic smooth muscle contraction +is_a: GO:0120063 ! stomach smooth muscle contraction + +[Term] +id: GO:0014848 +name: urinary tract smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551] +is_a: GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0014849 +name: ureter smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378] +is_a: GO:0014821 ! phasic smooth muscle contraction +is_a: GO:0014848 ! urinary tract smooth muscle contraction + +[Term] +id: GO:0014850 +name: response to muscle activity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus." [GOC:mtg_muscle] +is_a: GO:0014823 ! response to activity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0014852 +name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014819 ! regulation of skeletal muscle contraction + +[Term] +id: GO:0014853 +name: regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction +namespace: biological_process +def: "Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:ef, GOC:mtg_muscle] +synonym: "regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction" EXACT [] +is_a: GO:0098815 ! modulation of excitatory postsynaptic potential +intersection_of: GO:0098815 ! modulation of excitatory postsynaptic potential +intersection_of: part_of GO:0003009 ! skeletal muscle contraction +relationship: part_of GO:0003009 ! skeletal muscle contraction +relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction + +[Term] +id: GO:0014854 +name: response to inactivity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus." [GOC:mtg_muscle] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0014855 +name: striated muscle cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] +is_a: GO:0033002 ! muscle cell proliferation + +[Term] +id: GO:0014856 +name: skeletal muscle cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] +is_a: GO:0014855 ! striated muscle cell proliferation + +[Term] +id: GO:0014857 +name: regulation of skeletal muscle cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014856 ! skeletal muscle cell proliferation +relationship: regulates GO:0014856 ! skeletal muscle cell proliferation + +[Term] +id: GO:0014858 +name: positive regulation of skeletal muscle cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014856 ! skeletal muscle cell proliferation +relationship: positively_regulates GO:0014856 ! skeletal muscle cell proliferation + +[Term] +id: GO:0014859 +name: negative regulation of skeletal muscle cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation +relationship: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation + +[Term] +id: GO:0014860 +name: neurotransmitter secretion involved in regulation of skeletal muscle contraction +namespace: biological_process +def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb] +synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007269 ! neurotransmitter secretion +intersection_of: GO:0007269 ! neurotransmitter secretion +intersection_of: part_of GO:0014819 ! regulation of skeletal muscle contraction +relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction + +[Term] +id: GO:0014861 +name: regulation of skeletal muscle contraction via regulation of action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] +synonym: "regulation of skeletal muscle contraction via membrane action potential" RELATED [] +is_a: GO:0014819 ! regulation of skeletal muscle contraction +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential +relationship: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential + +[Term] +id: GO:0014862 +name: regulation of skeletal muscle contraction by chemo-mechanical energy conversion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres." [GOC:mtg_muscle] +is_a: GO:0014819 ! regulation of skeletal muscle contraction + +[Term] +id: GO:0014863 +name: detection of inactivity +namespace: biological_process +def: "The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal." [GOC:mtg_muscle] +is_a: GO:0014854 ! response to inactivity +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0014864 +name: detection of muscle activity +namespace: biological_process +def: "The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_muscle] +is_a: GO:0014850 ! response to muscle activity +is_a: GO:0014865 ! detection of activity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0014865 +name: detection of activity +namespace: biological_process +def: "The series of events in which an activity stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_muscle] +is_a: GO:0014823 ! response to activity +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0014866 +name: skeletal myofibril assembly +namespace: biological_process +def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0030239 ! myofibril assembly + +[Term] +id: GO:0014868 +name: cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction +namespace: biological_process +def: "A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction." [GOC:mtg_muscle] +is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction + +[Term] +id: GO:0014869 +name: detection of muscle inactivity +namespace: biological_process +def: "The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_muscle] +is_a: GO:0014863 ! detection of inactivity +is_a: GO:0014870 ! response to muscle inactivity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0014870 +name: response to muscle inactivity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus." [GOC:mtg_muscle] +is_a: GO:0014854 ! response to inactivity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0014871 +name: cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction +namespace: biological_process +def: "The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction." [GOC:mtg_muscle] +is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction + +[Term] +id: GO:0014872 +name: myoblast division +namespace: biological_process +def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0014873 +name: response to muscle activity involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "response to fatigue" EXACT [] +synonym: "response to muscle activity involved in regulation of muscle plasticity" RELATED [] +is_a: GO:0014850 ! response to muscle activity +is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation +intersection_of: GO:0014850 ! response to muscle activity +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014874 +name: response to stimulus involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "response to stimulus involved in regulation of muscle plasticity" RELATED [] +is_a: GO:0050896 ! response to stimulus +intersection_of: GO:0050896 ! response to stimulus +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation +relationship: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014875 +name: detection of muscle activity involved in regulation of muscle adaptation +namespace: biological_process +def: "The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "detection of fatigue" EXACT [] +is_a: GO:0014864 ! detection of muscle activity +is_a: GO:0014873 ! response to muscle activity involved in regulation of muscle adaptation +intersection_of: GO:0014864 ! detection of muscle activity +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014876 +name: response to injury involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "response to injury involved in regulation of muscle plasticity" RELATED [] +is_a: GO:0009611 ! response to wounding +is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation + +[Term] +id: GO:0014877 +name: response to muscle inactivity involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014870 ! response to muscle inactivity +is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation +intersection_of: GO:0014870 ! response to muscle inactivity +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014878 +name: response to electrical stimulus involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "response to electrical stimulus involved in regulation of muscle plasticity" RELATED [] +is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation +is_a: GO:0051602 ! response to electrical stimulus +intersection_of: GO:0051602 ! response to electrical stimulus +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014879 +name: detection of electrical stimulus involved in regulation of muscle adaptation +namespace: biological_process +def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation +is_a: GO:0050981 ! detection of electrical stimulus +intersection_of: GO:0050981 ! detection of electrical stimulus +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014880 +name: regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb] +is_a: GO:0032971 ! regulation of muscle filament sliding +relationship: part_of GO:0014729 ! regulation of the velocity of shortening of skeletal muscle modulating contraction + +[Term] +id: GO:0014881 +name: regulation of myofibril size +namespace: biological_process +def: "Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [GOC:dph, GOC:ef, GOC:mtg_muscle, GOC:tb] +synonym: "change of myofibril size" EXACT [] +is_a: GO:0014743 ! regulation of muscle hypertrophy +is_a: GO:0032535 ! regulation of cellular component size + +[Term] +id: GO:0014882 +name: regulation of myofibril number +namespace: biological_process +def: "Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [GOC:dph, GOC:ef, GOC:mtg_muscle, GOC:tb] +synonym: "change of myofibril number" EXACT [] +is_a: GO:0014738 ! regulation of muscle hyperplasia +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0014883 +name: transition between fast and slow fiber +namespace: biological_process +def: "The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation." [GOC:ef, GOC:mtg_muscle] +synonym: "transition between fast and slow fibre" EXACT [] +synonym: "transition fast-slow fiber" EXACT [] +synonym: "transition fast-slow fibre" EXACT [] +is_a: GO:0014733 ! regulation of skeletal muscle adaptation + +[Term] +id: GO:0014884 +name: detection of muscle inactivity involved in regulation of muscle adaptation +namespace: biological_process +def: "The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +is_a: GO:0014869 ! detection of muscle inactivity +is_a: GO:0014877 ! response to muscle inactivity involved in regulation of muscle adaptation +intersection_of: GO:0014869 ! detection of muscle inactivity +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014885 +name: detection of injury involved in regulation of muscle adaptation +namespace: biological_process +def: "The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] +synonym: "detection of injury involved in regulation of muscle plasticity" RELATED [] +is_a: GO:0014822 ! detection of wounding +is_a: GO:0014876 ! response to injury involved in regulation of muscle adaptation +intersection_of: GO:0014822 ! detection of wounding +intersection_of: part_of GO:0043502 ! regulation of muscle adaptation + +[Term] +id: GO:0014886 +name: transition between slow and fast fiber +namespace: biological_process +def: "The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation." [GOC:ef, GOC:mtg_muscle] +synonym: "transition between slow and fast fibre" EXACT [] +synonym: "transition slow-fast fiber" EXACT [] +synonym: "transition slow-fast fibre" EXACT [] +is_a: GO:0014733 ! regulation of skeletal muscle adaptation + +[Term] +id: GO:0014887 +name: cardiac muscle adaptation +namespace: biological_process +def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle] +synonym: "cardiac muscle plasticity" RELATED [] +is_a: GO:0014888 ! striated muscle adaptation + +[Term] +id: GO:0014888 +name: striated muscle adaptation +namespace: biological_process +def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] +synonym: "striated muscle plasticity" RELATED [] +is_a: GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014889 +name: muscle atrophy +namespace: biological_process +def: "A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse." [GOC:mtg_muscle] +comment: GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process. +xref: Wikipedia:Muscle_atrophy +is_a: GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014890 +name: smooth muscle atrophy +namespace: biological_process +def: "A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse." [GOC:mtg_muscle] +is_a: GO:0014805 ! smooth muscle adaptation +is_a: GO:0014889 ! muscle atrophy + +[Term] +id: GO:0014891 +name: striated muscle atrophy +namespace: biological_process +def: "A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse." [GOC:mtg_muscle] +is_a: GO:0014888 ! striated muscle adaptation +is_a: GO:0014889 ! muscle atrophy + +[Term] +id: GO:0014893 +name: response to rest involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:mtg_muscle] +is_a: GO:0014877 ! response to muscle inactivity involved in regulation of muscle adaptation + +[Term] +id: GO:0014894 +name: response to denervation involved in regulation of muscle adaptation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:mtg_muscle] +is_a: GO:0014877 ! response to muscle inactivity involved in regulation of muscle adaptation + +[Term] +id: GO:0014895 +name: smooth muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle] +is_a: GO:0014805 ! smooth muscle adaptation +is_a: GO:0014896 ! muscle hypertrophy + +[Term] +id: GO:0014896 +name: muscle hypertrophy +namespace: biological_process +def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle] +xref: Wikipedia:Muscle_hypertrophy +is_a: GO:0003012 ! muscle system process + +[Term] +id: GO:0014897 +name: striated muscle hypertrophy +namespace: biological_process +def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] +is_a: GO:0014896 ! muscle hypertrophy + +[Term] +id: GO:0014898 +name: cardiac muscle hypertrophy in response to stress +namespace: biological_process +def: "The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] +is_a: GO:0003299 ! muscle hypertrophy in response to stress +is_a: GO:0003300 ! cardiac muscle hypertrophy +is_a: GO:0014887 ! cardiac muscle adaptation + +[Term] +id: GO:0014899 +name: cardiac muscle atrophy +namespace: biological_process +def: "A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation." [GOC:mtg_muscle] +is_a: GO:0014887 ! cardiac muscle adaptation +is_a: GO:0014891 ! striated muscle atrophy + +[Term] +id: GO:0014900 +name: muscle hyperplasia +namespace: biological_process +def: "A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ." [GOC:mtg_muscle] +is_a: GO:0043500 ! muscle adaptation + +[Term] +id: GO:0014901 +name: satellite cell activation involved in skeletal muscle regeneration +namespace: biological_process +def: "The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:mtg_muscle] +is_a: GO:0014719 ! skeletal muscle satellite cell activation +intersection_of: GO:0014719 ! skeletal muscle satellite cell activation +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014902 +name: myotube differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] +is_a: GO:0051146 ! striated muscle cell differentiation + +[Term] +id: GO:0014904 +name: myotube cell development +namespace: biological_process +def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] +is_a: GO:0055002 ! striated muscle cell development +relationship: part_of GO:0014902 ! myotube differentiation + +[Term] +id: GO:0014905 +name: myoblast fusion involved in skeletal muscle regeneration +namespace: biological_process +def: "A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle] +is_a: GO:0007520 ! myoblast fusion +intersection_of: GO:0007520 ! myoblast fusion +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014908 ! myotube differentiation involved in skeletal muscle regeneration + +[Term] +id: GO:0014906 +name: myotube cell development involved in skeletal muscle regeneration +namespace: biological_process +def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] +is_a: GO:0014904 ! myotube cell development +intersection_of: GO:0014904 ! myotube cell development +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0014908 ! myotube differentiation involved in skeletal muscle regeneration + +[Term] +id: GO:0014908 +name: myotube differentiation involved in skeletal muscle regeneration +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] +is_a: GO:0014902 ! myotube differentiation +intersection_of: GO:0014902 ! myotube differentiation +intersection_of: part_of GO:0043403 ! skeletal muscle tissue regeneration +relationship: part_of GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0014909 +name: smooth muscle cell migration +namespace: biological_process +def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle] +is_a: GO:0014812 ! muscle cell migration + +[Term] +id: GO:0014910 +name: regulation of smooth muscle cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014909 ! smooth muscle cell migration +relationship: regulates GO:0014909 ! smooth muscle cell migration + +[Term] +id: GO:0014911 +name: positive regulation of smooth muscle cell migration +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] +is_a: GO:0014910 ! regulation of smooth muscle cell migration +is_a: GO:0030335 ! positive regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014909 ! smooth muscle cell migration +relationship: positively_regulates GO:0014909 ! smooth muscle cell migration + +[Term] +id: GO:0014912 +name: negative regulation of smooth muscle cell migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] +is_a: GO:0014910 ! regulation of smooth muscle cell migration +is_a: GO:0030336 ! negative regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014909 ! smooth muscle cell migration +relationship: negatively_regulates GO:0014909 ! smooth muscle cell migration + +[Term] +id: GO:0014914 +name: myoblast maturation involved in muscle regeneration +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:mtg_muscle] +is_a: GO:0048628 ! myoblast maturation + +[Term] +id: GO:0014915 +name: regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction +namespace: biological_process +def: "Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb] +is_a: GO:0014880 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction +is_a: GO:0032972 ! regulation of muscle filament sliding speed + +[Term] +id: GO:0014916 +name: regulation of lung blood pressure +namespace: biological_process +def: "The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure." [GOC:mtg_cardio] +synonym: "regulation of pulmonary blood pressure" EXACT [] +is_a: GO:0008217 ! regulation of blood pressure + +[Term] +id: GO:0014917 +name: obsolete positive regulation of diuresis by pressure natriuresis +namespace: biological_process +def: "OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "positive regulation of diuresis by pressure natriuresis" EXACT [] +is_obsolete: true +replaced_by: GO:0035818 + +[Term] +id: GO:0014918 +name: obsolete positive regulation of natriuresis by pressure natriuresis +namespace: biological_process +def: "OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis." [GOC:mtg_cardio] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "positive regulation of natriuresis by pressure natriuresis" EXACT [] +is_obsolete: true +replaced_by: GO:0035819 + +[Term] +id: GO:0015000 +name: obsolete polyferredoxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a function. +synonym: "polyferredoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015001 +name: obsolete high-potential iron-sulfur carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "high-potential iron-sulfur carrier" EXACT [] +synonym: "high-potential iron-sulphur carrier" EXACT [] +synonym: "HiPIP" RELATED [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015002 +name: heme-copper terminal oxidase activity +namespace: molecular_function +def: "Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane." [GOC:kd] +synonym: "haem-copper terminal oxidase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0015003 +name: obsolete copper electron carrier +namespace: molecular_function +def: "OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system." [GOC:ai] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "copper electron carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015004 +name: obsolete small blue copper electron carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "small blue copper electron carrier" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015005 +name: obsolete azurin +namespace: molecular_function +def: "OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin." [ISBN:0198547684] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "azurin" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0015006 +name: obsolete plastocyanin +namespace: molecular_function +def: "OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I." [ISBN:0198547684] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "plastocyanin" EXACT [] +is_obsolete: true +replaced_by: GO:0046028 + +[Term] +id: GO:0015007 +name: obsolete electron carrier, chlorophyll electron transport system +namespace: molecular_function +def: "OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system." [ISBN:0198506732] +comment: This term was made obsolete because it contains both process and function information. +synonym: "chlorophyll electron carrier" RELATED [] +synonym: "electron carrier, chlorophyll electron transport system" EXACT [] +is_obsolete: true +consider: GO:0009055 +consider: GO:0009767 + +[Term] +id: GO:0015009 +name: corrin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule." [GOC:ai, ISBN:0198506732] +synonym: "corrin metabolism" EXACT [] +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0015010 +name: tetrahydrocorphin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins." [Wikipedia:Morphine] +synonym: "tetrahydrocorphin metabolism" EXACT [] +is_a: GO:0015011 ! nickel-tetrapyrrole coenzyme metabolic process + +[Term] +id: GO:0015011 +name: nickel-tetrapyrrole coenzyme metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase." [GOC:mah, Wikipedia:Cofactor_F430] +synonym: "coenzyme F430 metabolic process" NARROW [] +synonym: "nickel-tetrapyrrole coenzyme metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0033013 ! tetrapyrrole metabolic process + +[Term] +id: GO:0015012 +name: heparan sulfate proteoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues." [GOC:mah, ISBN:0198506732, ISBN:0198547684, RESID:AA0210] +synonym: "heparan sulfate proteoglycan anabolism" EXACT [] +synonym: "heparan sulfate proteoglycan biosynthesis" EXACT [] +synonym: "heparan sulfate proteoglycan formation" EXACT [] +synonym: "heparan sulfate proteoglycan synthesis" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthesis" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthetic process" EXACT [] +synonym: "heparin proteoglycan biosynthetic process" RELATED [] +xref: RESID:AA0210 +is_a: GO:0030166 ! proteoglycan biosynthetic process +is_a: GO:0030201 ! heparan sulfate proteoglycan metabolic process + +[Term] +id: GO:0015013 +name: heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide +namespace: biological_process +def: "The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan." [ISBN:0815316194] +synonym: "heparan sulfate proteoglycan anabolism, linkage to polypeptide" EXACT [] +synonym: "heparan sulfate proteoglycan formation, linkage to polypeptide" EXACT [] +synonym: "heparan sulfate proteoglycan synthesis, linkage to polypeptide" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthesis, linkage to polypeptide" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide" EXACT [] +synonym: "heparin proteoglycan biosynthetic process, linkage to polypeptide" RELATED [] +is_a: GO:0018242 ! protein O-linked glycosylation via serine +is_a: GO:0030201 ! heparan sulfate proteoglycan metabolic process +relationship: part_of GO:0015012 ! heparan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0015014 +name: heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan." [GOC:ai] +synonym: "heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [] +synonym: "heparan sulfate proteoglycan chain elongation" EXACT [] +synonym: "heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [] +synonym: "heparan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [] +synonym: "heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [] +synonym: "heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" RELATED [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +relationship: part_of GO:0015012 ! heparan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0015015 +name: heparan sulfate proteoglycan biosynthetic process, enzymatic modification +namespace: biological_process +def: "The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization." [ISBN:0815316194] +synonym: "heparan sulfate proteoglycan anabolism, enzymatic modification" EXACT [] +synonym: "heparan sulfate proteoglycan formation, enzymatic modification" EXACT [] +synonym: "heparan sulfate proteoglycan synthesis, enzymatic modification" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthesis, enzymatic modification" EXACT [] +synonym: "heparan sulphate proteoglycan biosynthetic process, enzymatic modification" EXACT [] +synonym: "heparin proteoglycan biosynthetic process, enzymatic modification" RELATED [] +is_a: GO:0030201 ! heparan sulfate proteoglycan metabolic process +relationship: part_of GO:0015012 ! heparan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0015016 +name: [heparan sulfate]-glucosamine N-sulfotransferase activity +namespace: molecular_function +alt_id: GO:0004393 +alt_id: GO:0015022 +alt_id: GO:0051910 +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine." [EC:2.8.2.8] +comment: Note that this activity includes EC:2.8.2.12 (deleted from EC). +synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "[heparan sulphate]-glucosamine N-sulphotransferase activity" EXACT [] +synonym: "desulfoheparin sulfotransferase activity" EXACT [] +synonym: "glucosaminyl N-deacetylase/N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "heparan sulfate 2-N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "heparan sulfate N-deacetylase/N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "heparan sulfate N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "heparin N-deacetylase/N-sulfotransferase activity" RELATED [] +synonym: "heparin N-deacetylase/N-sulphotransferase activity" RELATED [] +synonym: "heparin N-sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "heparin-glucosamine N-sulfotransferase activity" EXACT [] +synonym: "heparitin N-sulfotransferase activity" EXACT [] +synonym: "heparitin N-sulphotransferase activity" EXACT [] +synonym: "heparitin sulfotransferase activity" EXACT [] +synonym: "N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "N-heparan sulfate sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "N-HSST activity" EXACT [EC:2.8.2.8] +synonym: "PAPS:DSH sulfotransferase activity" EXACT [EC:2.8.2.8] +synonym: "PAPS:N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] +xref: EC:2.8.2.8 +xref: MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-2022860 "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)" +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0015017 +name: obsolete glypican +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product (was misspelled 'glycipan'). +synonym: "glypican" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015018 +name: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein." [EC:2.4.1.135] +synonym: "glucuronosyltransferase I activity" NARROW [EC:2.4.1.135] +synonym: "UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" EXACT [EC:2.4.1.135] +synonym: "UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" EXACT [EC:2.4.1.135] +synonym: "uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity" EXACT [EC:2.4.1.135] +xref: EC:2.4.1.135 +xref: MetaCyc:2.4.1.135-RXN +xref: Reactome:R-HSA-1889955 "B3GAT dimers transfer GlcA to tetrasaccharide linker" +xref: Reactome:R-HSA-3560802 "Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker" +xref: Reactome:R-HSA-9638064 "B3GAT3 dimer transfers GlcA to tetrasaccharide linker" +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0015019 +name: heparan-alpha-glucosaminide N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide." [EC:2.3.1.78] +synonym: "acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity" EXACT [EC:2.3.1.78] +synonym: "acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity" EXACT [EC:2.3.1.78] +synonym: "heparin-alpha-glucosaminide N-acetyltransferase activity" RELATED [] +xref: EC:2.3.1.78 +xref: MetaCyc:2.3.1.78-RXN +xref: Reactome:R-HSA-1678660 "HGSNAT oligomer acetylates Heparan sulfate chain(3)" +xref: Reactome:R-HSA-2090085 "HGSNAT oligomer acetylates Heparan chain(1)" +xref: Reactome:R-HSA-2263492 "Defective HGSNAT does not acetylate Heparan chain(1)" +xref: Reactome:R-HSA-9036056 "Defective HGSNAT does not acetylate Heparan sulfate chain(3)" +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0015020 +name: glucuronosyltransferase activity +namespace: molecular_function +alt_id: GO:0003981 +def: "Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside." [EC:2.4.1.17] +synonym: "1-naphthol glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "1-naphthol-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "17-OH steroid UDPGT activity" NARROW [EC:2.4.1.17] +synonym: "17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "3-OH androgenic UDPGT activity" NARROW [EC:2.4.1.17] +synonym: "3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "4-nitrophenol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "4-nitrophenol UDPGT activity" NARROW [EC:2.4.1.17] +synonym: "bilirubin glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "bilirubin monoglucuronide glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "bilirubin UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "bilirubin UDPGT activity" NARROW [EC:2.4.1.17] +synonym: "bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "ciramadol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "estriol UDPglucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "estrone UDPglucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "GT activity" EXACT [EC:2.4.1.17] +synonym: "morphine glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "p-nitrophenol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "p-nitrophenylglucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "p-phenylphenol glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "phenyl-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "PNP-UDPGT" RELATED [EC:2.4.1.17] +synonym: "pnp-UDPGT activity" NARROW [EC:2.4.1.17] +synonym: "UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "UDP glucuronic acid transferase activity" EXACT [EC:2.4.1.17] +synonym: "UDP glucuronosyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "UDP glucuronyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [EC:2.4.1.17] +synonym: "UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "UDP-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "UDP-glucuronyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "UDPGA transferase activity" EXACT [EC:2.4.1.17] +synonym: "UDPGA-glucuronyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [EC:2.4.1.17] +synonym: "UDPGT activity" EXACT [EC:2.4.1.17] +synonym: "uridine 5'-diphosphoglucuronyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "uridine diphosphate glucuronyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronosyltransferase activity" EXACT [EC:2.4.1.17] +synonym: "uridine diphosphoglucuronyltransferase activity" EXACT [EC:2.4.1.17] +xref: EC:2.4.1.17 +xref: MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-159179 "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG" +xref: Reactome:R-HSA-159194 "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG" +xref: Reactome:R-HSA-174916 "Formation of N-glucuronides" +xref: Reactome:R-HSA-174931 "UGTs transfer GlcA from UDP-GlcA to O-centre substrates" +xref: Reactome:R-HSA-2162099 "abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP" +xref: Reactome:R-HSA-5604954 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL" +xref: Reactome:R-HSA-5604975 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL" +xref: Reactome:R-HSA-5617143 "B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA" +xref: Reactome:R-HSA-8941701 "UGT1A10 transfers GlcA from UDP-GlcA to GCTN" +xref: Reactome:R-HSA-9036102 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG" +xref: Reactome:R-HSA-9036104 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG" +xref: Reactome:R-HSA-9632038 "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG" +xref: Reactome:R-HSA-9632039 "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG" +xref: Reactome:R-HSA-9638097 "B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0015021 +name: heparin-sulfate lyase activity +namespace: molecular_function +def: "Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar." [EC:4.2.2.8] +synonym: "[heparan sulfate]-sulfate lyase activity" RELATED [] +synonym: "heparin-sulfate eliminase activity" RELATED [EC:4.2.2.8] +synonym: "heparin-sulphate lyase activity" EXACT [] +synonym: "heparitin-sulfate lyase activity" EXACT [] +synonym: "heparitinase I" RELATED [EC:4.2.2.8] +synonym: "heparitinase II" RELATED [EC:4.2.2.8] +xref: EC:4.2.2.8 +xref: MetaCyc:4.2.2.8-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0015023 +name: obsolete syndecan +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "syndecan" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015024 +name: glucuronate-2-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate." [EC:3.1.6.18] +synonym: "chondro-2-sulfatase activity" EXACT [EC:3.1.6.18] +synonym: "glucuronate-2-sulphatase activity" EXACT [] +synonym: "glucurono-2-sulfatase activity" EXACT [EC:3.1.6.18] +synonym: "polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity" EXACT [EC:3.1.6.18] +xref: EC:3.1.6.18 +xref: MetaCyc:3.1.6.18-RXN +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0015025 +name: obsolete GPI-anchored membrane-bound receptor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "GPI-anchored membrane-bound receptor" EXACT [] +is_obsolete: true +replaced_by: GO:0031225 + +[Term] +id: GO:0015026 +name: coreceptor activity +namespace: molecular_function +alt_id: GO:0015027 +alt_id: GO:0015028 +def: "Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity." [GOC:go_curators] +synonym: "coreceptor, insoluble ligand activity" RELATED [GOC:mah] +synonym: "coreceptor, soluble ligand activity" RELATED [GOC:mah] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0015029 +name: obsolete internalization receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because internalization is a process, not a ligand to which a receptor might bind. +synonym: "internalization receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015030 +name: Cajal body +namespace: cellular_component +def: "A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA." [NIF_Subcellular:nlx_subcell_090901, PMID:10944589, PMID:11031238, PMID:7559785] +synonym: "coiled body" EXACT [] +synonym: "Gemini of coiled bodies" RELATED [] +synonym: "Gems" RELATED [] +xref: NIF_Subcellular:nlx_subcell_090901 +xref: Wikipedia:Cajal_body +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0015031 +name: protein transport +namespace: biological_process +alt_id: GO:0015831 +def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_yeast +synonym: "enzyme transport" NARROW [] +is_a: GO:0015833 ! peptide transport +is_a: GO:0045184 ! establishment of protein localization + +[Term] +id: GO:0015032 +name: obsolete storage protein import into fat body +namespace: biological_process +def: "OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life." [GOC:bf, PMID:10231363] +comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using 'receptor-mediated endocytosis'. +synonym: "fat body metabolic process" BROAD [] +synonym: "fat body metabolism" BROAD [] +synonym: "fat body storage protein uptake" EXACT [] +synonym: "import of storage protein into fat body" EXACT [] +synonym: "storage protein import by fat body cells" EXACT [] +synonym: "storage protein import into fat body cells" EXACT [] +synonym: "storage protein transport into fat body cells" EXACT [] +synonym: "storage protein uptake into fat body cells" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12935 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0015034 +name: obsolete cytochrome P450 activity +namespace: molecular_function +def: "OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer." [ISBN:0198547684, PMID:1655423] +comment: This term was made obsolete because it is a grouping term representing a set of gene products. +synonym: "cytochrome P450 activity" EXACT [] +is_obsolete: true +consider: GO:0019825 + +[Term] +id: GO:0015035 +name: protein disulfide oxidoreductase activity +namespace: molecular_function +alt_id: GO:0008895 +def: "Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds." [MetaCyc:DISULFOXRED-RXN] +synonym: "haem lyase disulphide oxidoreductase activity" NARROW [] +synonym: "heme lyase disulfide oxidoreductase activity" NARROW [] +synonym: "protein disulphide oxidoreductase activity" EXACT [] +synonym: "thioredoxin activity" NARROW [GOC:mah, GOC:vw] +xref: MetaCyc:DISULFOXRED-RXN +xref: Reactome:R-HSA-1307802 "MIA40:ERV1 (CHCHD4:GFER) oxidizes cysteine residues to cystine disulfide bonds" +xref: Reactome:R-HSA-3299753 "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1" +is_a: GO:0015036 ! disulfide oxidoreductase activity + +[Term] +id: GO:0015036 +name: disulfide oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds." [MetaCyc:DISULFOXRED-RXN] +synonym: "disulphide oxidoreductase activity" EXACT [] +xref: Reactome:R-HSA-1222417 "TrxA reactivates AhpC" +xref: Reactome:R-HSA-1222644 "TrxA/B1 reactivates Tpx" +xref: Reactome:R-HSA-1222655 "AhpD reactivates AhpC" +xref: Reactome:R-HSA-1222690 "DlaT reactivates AhpD" +xref: Reactome:R-HSA-264997 "Oxidation of cysteine to cystine in Proinsulin" +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0015037 +name: peptide disulfide oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds." [GOC:mah, MetaCyc:DISULFOXRED-RXN] +synonym: "peptide disulphide oxidoreductase activity" EXACT [] +is_a: GO:0015036 ! disulfide oxidoreductase activity + +[Term] +id: GO:0015038 +name: glutathione disulfide oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor." [GOC:mah] +synonym: "glutaredoxin" RELATED [] +synonym: "glutathione disulphide oxidoreductase activity" EXACT [] +xref: Reactome:R-HSA-111746 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)" +is_a: GO:0015037 ! peptide disulfide oxidoreductase activity + +[Term] +id: GO:0015039 +name: NADPH-adrenodoxin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+." [EC:1.18.1.6, GOC:kd] +comment: Note that this term specifically refers to the reaction proceeding in the direction shown; under physiological conditions adrenodoxin reduction by adrenodoxin reductase is coupled with electron transfer from AdR to P450, which catalyzes an irreversible monooxygenation reaction. This term should therefore be used to annotate gene products that catalyze the reduction of oxidized adrenodoxin; also consider annotating to the molecular function term 'ferredoxin-NADP+ reductase activity ; GO:0004324'. +synonym: "adrenodoxin reductase activity" BROAD [EC:1.18.1.2] +synonym: "adrenodoxin-type ferredoxin reductase activity" EXACT [GOC:kd] +synonym: "NADPH:adrenodoxin oxidoreductase activity" EXACT [EC:1.18.1.2] +xref: EC:1.18.1.6 +xref: MetaCyc:RXN-13685 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0015040 +name: obsolete electron transfer flavoprotein, group I +namespace: molecular_function +def: "OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway." [PMID:8599534] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "electron transfer flavoprotein, group I" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015041 +name: obsolete electron transfer flavoprotein, group II +namespace: molecular_function +def: "OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation." [PMID:8599534] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "electron transfer flavoprotein, group II" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015042 +name: trypanothione-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide." [EC:1.8.1.12] +comment: Note that this function was formerly EC:1.6.4.8. +synonym: "N(1),N(8)-bis(glutathionyl)spermidine reductase activity" EXACT [EC:1.8.1.12] +synonym: "N1,N8-bis(glutathionyl)spermidine reductase activity" EXACT [EC:1.8.1.12] +synonym: "NADPH2:trypanothione oxidoreductase activity" EXACT [EC:1.8.1.12] +synonym: "NADPH:trypanothione oxidoreductase activity" EXACT [EC:1.8.1.12] +synonym: "trypanothione reductase activity" EXACT [] +synonym: "trypanothione-disulphide reductase activity" EXACT [] +synonym: "trypanothione:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.12] +xref: EC:1.8.1.12 +xref: MetaCyc:1.8.1.12-RXN +xref: RHEA:16757 +is_a: GO:0015036 ! disulfide oxidoreductase activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0015043 +name: leghemoglobin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin." [EC:1.6.2.6] +synonym: "ferric leghemoglobin reductase activity" EXACT [EC:1.6.2.6] +synonym: "NAD(P)H:ferrileghemoglobin oxidoreductase activity" EXACT [EC:1.6.2.6] +xref: EC:1.6.2.6 +xref: MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN +is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor + +[Term] +id: GO:0015044 +name: rubredoxin-NAD+ reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+." [EC:1.18.1.1] +synonym: "dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity" EXACT [EC:1.18.1.1] +synonym: "DPNH-rubredoxin reductase activity" EXACT [EC:1.18.1.1] +synonym: "NADH--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.1] +synonym: "NADH--rubredoxin reductase activity" EXACT [EC:1.18.1.1] +synonym: "NADH:rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.1] +synonym: "NADH:rubredoxin reductase activity" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity" EXACT [EC:1.18.1.1] +synonym: "rubredoxin--NAD reductase activity" EXACT [EC:1.18.1.1] +synonym: "rubredoxin--nicotinamide adenine dinucleotide reductase activity" EXACT [EC:1.18.1.1] +synonym: "rubredoxin:NAD+ oxidoreductase activity" EXACT [EC:1.18.1.1] +xref: EC:1.18.1.1 +xref: MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN +is_a: GO:0015045 ! rubredoxin-NAD(P)+ reductase activity + +[Term] +id: GO:0015045 +name: rubredoxin-NAD(P)+ reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+." [EC:1.18.1.4] +synonym: "dinucleotide phosphate reductase activity" RELATED [EC:1.18.1.4] +synonym: "NAD(P)--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.4] +synonym: "NAD(P)H--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.4] +synonym: "NADPH:rubredoxin reductase activity" EXACT [] +synonym: "rubredoxin--nicotinamide adenine activity" RELATED [EC:1.18.1.4] +synonym: "rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity" EXACT [EC:1.18.1.4] +synonym: "rubredoxin:NAD(P)+ oxidoreductase activity" EXACT [EC:1.18.1.4] +xref: EC:1.18.1.4 +xref: MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN +is_a: GO:0016731 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor + +[Term] +id: GO:0015046 +name: rubredoxin-NADP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+." [EC:1.18.1.-] +xref: EC:1.18.1 +is_a: GO:0015045 ! rubredoxin-NAD(P)+ reductase activity + +[Term] +id: GO:0015047 +name: NADPH-cytochrome-c2 reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2." [EC:1.6.2.5] +synonym: "cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)" EXACT [EC:1.6.2.5] +synonym: "NADPH:ferricytochrome-c2 oxidoreductase activity" EXACT [EC:1.6.2.5] +synonym: "reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.6.2.5] +xref: EC:1.6.2.5 +xref: MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN +is_a: GO:0016653 ! oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor + +[Term] +id: GO:0015048 +name: phthalate dioxygenase reductase activity +namespace: molecular_function +def: "Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems." [PMID:7589982] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0015049 +name: methane monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O." [EC:1.14.13.25] +synonym: "methane hydroxylase activity" EXACT [EC:1.14.13.25] +synonym: "methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.25] +xref: EC:1.14.13.25 +xref: KEGG_REACTION:R01142 +xref: KEGG_REACTION:R01143 +xref: MetaCyc:METHANE-MONOOXYGENASE-RXN +xref: RHEA:13637 +xref: RHEA:13641 +xref: UM-BBD_enzymeID:e0007 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0015050 +name: methane monooxygenase complex +namespace: cellular_component +def: "A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized." [BRENDA:1.14.13.25, GOC:mah] +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0015051 +name: obsolete X-opioid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors." [InterPro:IPR001420] +comment: This term was made obsolete because the receptor is defined based on its pharmacological properties. +synonym: "X-opioid receptor activity" EXACT [] +is_obsolete: true +consider: GO:0001626 + +[Term] +id: GO:0015052 +name: beta3-adrenergic receptor activity +namespace: molecular_function +def: "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors." [GOC:mah, IUPHAR_GPCR:1274] +synonym: "beta3 adrenoceptor" EXACT [] +is_a: GO:0004939 ! beta-adrenergic receptor activity + +[Term] +id: GO:0015053 +name: obsolete opsin +namespace: molecular_function +def: "OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin." [ISBN:0198547684] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "opsin" EXACT [] +is_obsolete: true +consider: GO:0007602 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015054 +name: gastrin receptor activity +namespace: molecular_function +def: "Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity." [GOC:ai, GOC:signaling] +synonym: "cholecystokinin-B receptor activity" RELATED [] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0015055 +name: secretin receptor activity +namespace: molecular_function +def: "Combining with secretin to initiate a change in cell activity." [GOC:mah] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0015056 +name: corticotrophin-releasing factor receptor activity +namespace: molecular_function +def: "Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity." [PMID:12032352] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: part_of GO:0071376 ! cellular response to corticotropin-releasing hormone stimulus + +[Term] +id: GO:0015057 +name: thrombin-activated receptor activity +namespace: molecular_function +alt_id: GO:0010655 +def: "A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it." [GOC:ai, GOC:pg, PMID:20423334] +synonym: "thrombin receptor activity" EXACT [] +synonym: "thrombin receptor activity, G-protein coupled" EXACT [] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0070493 ! thrombin-activated receptor signaling pathway + +[Term] +id: GO:0015058 +name: obsolete epidermal growth factor-like module containing hormone receptor activity +namespace: molecular_function +alt_id: GO:0016523 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features. +synonym: "EGF-like module containing hormone receptor activity" EXACT [] +synonym: "Egr1 hormone receptor" EXACT [] +synonym: "epidermal growth factor-like module containing hormone receptor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015059 +name: obsolete blue-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "blue-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009588 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015060 +name: obsolete green-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "green-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015061 +name: obsolete red-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "red-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009585 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015062 +name: obsolete violet-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "violet-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009588 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015063 +name: obsolete long-wave-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. An opsin with maximal absorption above 500 nm." [PMID:10594055] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "long-wave-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015064 +name: obsolete UV-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. An opsin with maximal absorption below 400 nm." [PMID:10594055] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "UV-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007604 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0015066 +name: alpha-amylase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of alpha-amylase." [GOC:mah] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004556 ! alpha-amylase activity + +[Term] +id: GO:0015067 +name: amidinotransferase activity +namespace: molecular_function +def: "Catalysis of the reversible transfer of an amidino group to an acceptor." [GOC:ai] +synonym: "transamidinase activity" EXACT [] +xref: EC:2.1.4 +is_a: GO:0016741 ! transferase activity, transferring one-carbon groups +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups + +[Term] +id: GO:0015068 +name: glycine amidinotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate." [EC:2.1.4.1] +synonym: "arginine-glycine amidinotransferase activity" EXACT [EC:2.1.4.1] +synonym: "arginine-glycine transamidinase activity" EXACT [EC:2.1.4.1] +synonym: "glycine transamidinase activity" EXACT [EC:2.1.4.1] +synonym: "L-arginine:glycine amidinotransferase activity" EXACT [EC:2.1.4.1] +xref: EC:2.1.4.1 +xref: MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN +xref: Reactome:R-HSA-71275 "arginine + glycine => ornithine + guanidoacetate" +xref: RHEA:13201 +is_a: GO:0015067 ! amidinotransferase activity + +[Term] +id: GO:0015069 +name: scyllo-inosamine-4-phosphate amidinotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine." [EC:2.1.4.2, RHEA:13265] +synonym: "inosamine-P amidinotransferase activity" EXACT [EC:2.1.4.2] +synonym: "inosamine-phosphate amidinotransferase activity" EXACT [] +synonym: "L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity" EXACT [EC:2.1.4.2] +synonym: "L-arginine:inosamine phosphate amidinotransferase activity" EXACT [EC:2.1.4.2] +synonym: "L-arginine:inosamine-P-amidinotransferase activity" EXACT [EC:2.1.4.2] +xref: EC:2.1.4.2 +xref: KEGG_REACTION:R03477 +xref: MetaCyc:2.1.4.2-RXN +xref: RHEA:13265 +is_a: GO:0015067 ! amidinotransferase activity + +[Term] +id: GO:0015070 +name: obsolete toxin activity +namespace: molecular_function +def: "OBSOLETE. Acts as to cause injury to other living organisms." [GOC:jl] +comment: This term was made obsolete because it represents a classification of molecules and not a molecular function. +synonym: "toxin activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0015072 +name: obsolete phosphatidylinositol 3-kinase, class I, catalyst activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate." [EC:2.7.1.137] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" EXACT [] +is_obsolete: true +consider: GO:0016303 +consider: GO:0035005 +consider: GO:0046934 + +[Term] +id: GO:0015073 +name: obsolete phosphatidylinositol 3-kinase, class I, regulator activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate." [EC:2.7.1.137] +comment: This term was made obsolete because it refers to a class of gene products. +synonym: "phosphatidylinositol 3-kinase, class I, regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0046935 + +[Term] +id: GO:0015074 +name: DNA integration +namespace: biological_process +def: "The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome." [GOC:mah] +subset: goslim_pir +is_a: GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0015075 +name: ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] +synonym: "ion transporter activity" EXACT [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0015076 +name: obsolete heavy metal ion transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:ai] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "heavy metal ion transporter activity" EXACT [] +is_obsolete: true +consider: GO:0046873 + +[Term] +id: GO:0015077 +name: monovalent inorganic cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity +relationship: part_of GO:0015672 ! monovalent inorganic cation transport + +[Term] +id: GO:0015078 +name: proton transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a proton from one side of a membrane to the other." [GOC:ai] +synonym: "hydrogen ion transmembrane transporter activity" EXACT [] +synonym: "proton transporter activity" EXACT [] +xref: Reactome:R-HSA-1222516 "Intraphagosomal pH is lowered to 5 by V-ATPase" +xref: Reactome:R-HSA-164834 "Enzyme-bound ATP is released" +xref: Reactome:R-HSA-170026 "Protons are translocated from the intermembrane space to the matrix" +xref: Reactome:R-HSA-74723 "Endosome acidification" +xref: Reactome:R-HSA-917841 "Acidification of Tf:TfR1 containing endosome" +is_a: GO:0015077 ! monovalent inorganic cation transmembrane transporter activity +relationship: part_of GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0015079 +name: potassium ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015388 +alt_id: GO:0022817 +def: "Enables the transfer of potassium ions (K+) from one side of a membrane to the other." [GOC:ai] +synonym: "potassium transporter activity" EXACT [] +synonym: "potassium uptake permease activity" RELATED [] +synonym: "potassium uptake transmembrane transporter activity" RELATED [] +xref: RHEA:29463 +is_a: GO:0015077 ! monovalent inorganic cation transmembrane transporter activity +is_a: GO:0046873 ! metal ion transmembrane transporter activity +relationship: part_of GO:0071805 ! potassium ion transmembrane transport + +[Term] +id: GO:0015080 +name: silver ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of silver (Ag) ions from one side of a membrane to the other." [GOC:ai] +synonym: "silver transporter activity" EXACT [] +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:1902601 ! silver ion transmembrane transport + +[Term] +id: GO:0015081 +name: sodium ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0022816 +def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF] +synonym: "sodium transporter activity" EXACT [] +is_a: GO:0015077 ! monovalent inorganic cation transmembrane transporter activity +is_a: GO:0046873 ! metal ion transmembrane transporter activity +relationship: part_of GO:0035725 ! sodium ion transmembrane transport + +[Term] +id: GO:0015083 +name: aluminum ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015084 +def: "Enables the transfer of aluminum (Al) ions from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "aluminium ion transporter activity" EXACT [] +synonym: "aluminium resistance permease activity" EXACT [] +synonym: "aluminum resistance permease activity" EXACT [] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:1902602 ! aluminum ion transmembrane transport + +[Term] +id: GO:0015085 +name: calcium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other." [GOC:dgf] +xref: Reactome:R-HSA-2534359 "CatSper Channel Mediated Calcium Transport" +is_a: GO:0046873 ! metal ion transmembrane transporter activity +relationship: part_of GO:0070588 ! calcium ion transmembrane transport + +[Term] +id: GO:0015086 +name: cadmium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other." [GOC:dgf] +synonym: "zinc, cadmium uptake permease activity" RELATED [] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0070574 ! cadmium ion transmembrane transport + +[Term] +id: GO:0015087 +name: cobalt ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cobalt (Co) ions from one side of a membrane to the other." [GOC:dgf] +synonym: "cobalt, zinc uptake permease activity" RELATED [] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] +xref: RHEA:28578 +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0006824 ! cobalt ion transport + +[Term] +id: GO:0015089 +name: high-affinity copper ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:9.A.11.1.1] +synonym: "high affinity copper ion transmembrane transporter activity" EXACT [] +synonym: "high affinity copper transporter activity" EXACT [] +is_a: GO:0005375 ! copper ion transmembrane transporter activity + +[Term] +id: GO:0015090 +name: low-affinity ferric iron ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:9.A.9.1.1] +synonym: "low affinity iron ion transmembrane transporter activity" EXACT [] +synonym: "low affinity iron transporter activity" EXACT [] +is_a: GO:0015091 ! ferric iron transmembrane transporter activity + +[Term] +id: GO:0015091 +name: ferric iron transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other." [ISBN:0198506732] +comment: Ferric iron is rarely transported in the free form. Some bacteria have a system in which an outer membrane protein takes iron away from host ferritin or lactoferrin and transport it to a Fe3+ binding protein in the periplasm. The periplasmic protein then delivers the Fe3+ to a transport system located in the cytoplasmic membrane. Consider also GO:0015343 siderophore transmembrane transporter activity. +is_a: GO:0005381 ! iron ion transmembrane transporter activity +is_a: GO:0072510 ! trivalent inorganic cation transmembrane transporter activity + +[Term] +id: GO:0015092 +name: high-affinity ferric iron transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:ai, PMID:1447137] +synonym: "high affinity ferric uptake transmembrane transporter activity" RELATED [] +is_a: GO:0015091 ! ferric iron transmembrane transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14372 xsd:anyURI + +[Term] +id: GO:0015093 +name: ferrous iron transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015639 +def: "Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other." [ISBN:0198506732] +synonym: "ferrous iron uptake transmembrane transporter activity" RELATED [] +xref: Reactome:R-HSA-1362417 "Mitoferrin translocates iron from the mitochondrial intermembrane space to the mitochondrial matrix" +xref: Reactome:R-HSA-442368 "SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region" +xref: Reactome:R-HSA-5655760 "Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol" +xref: RHEA:28486 +is_a: GO:0005381 ! iron ion transmembrane transporter activity +is_a: GO:0072509 ! divalent inorganic cation transmembrane transporter activity + +[Term] +id: GO:0015094 +name: lead ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lead (Pb) ions from one side of a membrane to the other." [GOC:ai] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0015692 ! lead ion transport + +[Term] +id: GO:0015095 +name: magnesium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other." [GOC:dgf] +xref: Reactome:R-HSA-442661 "SLC41A1,2 transport Mg2+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5336453 "NIPAs transport Mg2+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5336454 "MMGT1 transports Mg2+ from cytosol to Golgi lumen" +xref: Reactome:R-HSA-5336466 "MRS2 transports Mg2+ from cytosol to mitochondrial matrix" +xref: Reactome:R-HSA-5339528 "TUSC3 transports Mg2+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5339538 "MAGT1 transports Mg2+ from extracellular region to cytosol" +xref: RHEA:29827 +is_a: GO:0046873 ! metal ion transmembrane transporter activity +relationship: part_of GO:1903830 ! magnesium ion transmembrane transport + +[Term] +id: GO:0015096 +name: obsolete manganese resistance permease activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because the term is undefined and we don't know the mechanism so we can't make a correct definition. +synonym: "manganese resistance permease activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015097 +name: mercury ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of mercury (Hg) ions from one side of a membrane to the other." [GOC:ai] +xref: RHEA:32815 +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0015694 ! mercury ion transport + +[Term] +id: GO:0015098 +name: molybdate ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid." [ISBN:0198506732] +synonym: "molybdate transporter activity" EXACT [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015689 ! molybdate ion transport + +[Term] +id: GO:0015099 +name: nickel cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nickel (Ni) cations from one side of a membrane to the other." [GOC:ai] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] +xref: RHEA:29831 +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0035444 ! nickel cation transmembrane transport + +[Term] +id: GO:0015100 +name: vanadium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of vanadium (V) ions from one side of a membrane to the other." [GOC:ai] +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0015676 ! vanadium ion transport + +[Term] +id: GO:0015101 +name: organic cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]" +xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells" +xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney" +xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations" +xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells" +xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney" +xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations" +is_a: GO:0008324 ! cation transmembrane transporter activity +relationship: part_of GO:0015695 ! organic cation transport + +[Term] +id: GO:0015103 +name: inorganic anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015104 +name: antimonite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of antimonite from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015699 ! antimonite transport + +[Term] +id: GO:0015105 +name: arsenite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of arsenite from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015700 ! arsenite transport + +[Term] +id: GO:0015106 +name: bicarbonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] +xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0015701 ! bicarbonate transport + +[Term] +id: GO:0015107 +name: chlorate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other." [GOC:curators] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015702 ! chlorate transport + +[Term] +id: GO:0015108 +name: chloride transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of chloride ions from one side of a membrane to the other." [GOC:ai] +synonym: "chloride ion transmembrane transporter activity" EXACT [GOC:pr] +xref: Reactome:R-HSA-5678822 "Defective CFTR does not transport Cl- from cytosol to extracellular region" +xref: Reactome:R-HSA-5678863 "CFTR transports Cl- from cytosol to extracellular region" +xref: Reactome:R-HSA-5678992 "Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region" +xref: RHEA:29823 +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:1902476 ! chloride transmembrane transport + +[Term] +id: GO:0015109 +name: chromate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3." [GOC:ai] +xref: RHEA:32819 +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015703 ! chromate transport + +[Term] +id: GO:0015110 +name: cyanate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0015704 ! cyanate transport + +[Term] +id: GO:0015111 +name: iodide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of iodide ions from one side of a membrane to the other." [GOC:ai] +xref: Reactome:R-HSA-209910 "Iodide is taken up by thyroid epithelial cells" +xref: Reactome:R-HSA-5627802 "SLC26A4 transports I- from cytosol to extracellular region" +xref: Reactome:R-HSA-5627870 "SLC26A4 does not transport I- from cytosol to extracellular region" +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015705 ! iodide transport + +[Term] +id: GO:0015112 +name: nitrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other." [GOC:ai] +synonym: "nitrite/nitrate porter activity" RELATED [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015706 ! nitrate transport + +[Term] +id: GO:0015113 +name: nitrite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other." [GOC:ai] +synonym: "nitrite/nitrate porter activity" RELATED [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015707 ! nitrite transport + +[Term] +id: GO:0015114 +name: phosphate ion transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901677 +def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] +synonym: "phosphate transmembrane transporter activity" RELATED [GOC:vw] +xref: RHEA:32823 +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0035435 ! phosphate ion transmembrane transport +created_by: pr +creation_date: 2012-11-22T15:43:10Z + +[Term] +id: GO:0015115 +name: silicate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates." [GOC:ai] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0015708 ! silicic acid import across plasma membrane + +[Term] +id: GO:0015116 +name: sulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] +synonym: "sulfate permease activity" RELATED [] +synonym: "sulphate transporter activity" EXACT [] +xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" +xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:1902358 ! sulfate transmembrane transport + +[Term] +id: GO:0015117 +name: thiosulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other." [GOC:ai] +synonym: "thiosulfate permease activity" RELATED [] +synonym: "thiosulphate transporter activity" EXACT [] +xref: RHEA:32807 +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0015709 ! thiosulfate transport + +[Term] +id: GO:0015119 +name: hexose phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015712 ! hexose phosphate transport + +[Term] +id: GO:0015120 +name: phosphoglycerate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis." [GOC:ai] +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0042879 ! aldonate transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015713 ! phosphoglycerate transmembrane transport + +[Term] +id: GO:0015121 +name: phosphoenolpyruvate:phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out)." [GOC:bf, GOC:jl] +synonym: "phosphoenolpyruvate/phosphate translocator" EXACT [] +synonym: "PPT" BROAD [PMID:10488230] +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015315 ! organophosphate:inorganic phosphate antiporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +is_a: GO:0089721 ! phosphoenolpyruvate transmembrane transporter activity + +[Term] +id: GO:0015123 +name: acetate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0035433 ! acetate transmembrane transport + +[Term] +id: GO:0015124 +name: allantoate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen." [GOC:ai, ISBN:0198547684] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0015719 ! allantoate transport + +[Term] +id: GO:0015125 +name: bile acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] +xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol" +xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol" +xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" +xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport ALB:(GCCA,TCCA) from extracellular region to cytosol" +xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport ALB:(GCCA, TCCA) from extracellular region to cytosol" +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0015721 ! bile acid and bile salt transport + +[Term] +id: GO:0015126 +name: canalicular bile acid transmembrane transporter activity +namespace: molecular_function +def: "The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:dph] +is_a: GO:0015125 ! bile acid transmembrane transporter activity +relationship: part_of GO:0015722 ! canalicular bile acid transport + +[Term] +id: GO:0015127 +name: bilirubin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] +xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" +xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015723 ! bilirubin transport + +[Term] +id: GO:0015128 +name: gluconate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose." [GOC:ai, ISBN:0198506732] +synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] +is_a: GO:0042879 ! aldonate transmembrane transporter activity +relationship: part_of GO:0035429 ! gluconate transmembrane transport + +[Term] +id: GO:0015129 +name: lactate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:ai, ISBN:0198506732] +synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" RELATED [] +xref: Reactome:R-HSA-373867 "BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-373875 "BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region" +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0035873 ! lactate transmembrane transport + +[Term] +id: GO:0015130 +name: mevalonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds." [GOC:ai, ISBN:0198506732] +synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" RELATED [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0015728 ! mevalonate transport + +[Term] +id: GO:0015131 +name: oxaloacetate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +relationship: part_of GO:1902356 ! oxaloacetate(2-) transmembrane transport + +[Term] +id: GO:0015132 +name: prostaglandin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities." [GOC:ai] +synonym: "prostaglandin/thromboxane transporter activity" BROAD [] +xref: Reactome:R-HSA-5661188 "Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol" +xref: Reactome:R-HSA-879528 "SLCO2A1 transports PGT substrates from extracellular region to cytosol" +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +is_a: GO:0071714 ! icosanoid transmembrane transporter activity +relationship: part_of GO:0015732 ! prostaglandin transport + +[Term] +id: GO:0015133 +name: uronic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose." [GOC:ai] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +relationship: part_of GO:0015735 ! uronic acid transmembrane transport + +[Term] +id: GO:0015134 +name: hexuronate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015163 +def: "Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6." [GOC:ai, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "hexuronide transmembrane transporter activity" EXACT [] +is_a: GO:0015133 ! uronic acid transmembrane transporter activity +relationship: part_of GO:0015736 ! hexuronate transmembrane transport +relationship: part_of GO:0015778 ! hexuronide transport + +[Term] +id: GO:0015135 +name: glucuronate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:ai] +is_a: GO:0015134 ! hexuronate transmembrane transporter activity +relationship: part_of GO:0015738 ! glucuronate transmembrane transport + +[Term] +id: GO:0015136 +name: sialic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sialic acid from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015739 ! sialic acid transport + +[Term] +id: GO:0015137 +name: citrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other." [GOC:ai] +synonym: "tricarboxylate transport protein" RELATED [TC:2.A.29.7.2] +xref: Reactome:R-HSA-433104 "NACT co-transports trivalent citrate and a sodium ion" +xref: TC:2.A.29.7.2 +is_a: GO:0015142 ! tricarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015746 ! citrate transport + +[Term] +id: GO:0015138 +name: fumarate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate." [GOC:ai] +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +relationship: part_of GO:0015741 ! fumarate transport + +[Term] +id: GO:0015139 +name: alpha-ketoglutarate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle." [GOC:ai, ISBN:0198547684] +synonym: "2-oxoglutarate transporter activity" EXACT [] +xref: Reactome:R-HSA-372480 "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]" +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015742 ! alpha-ketoglutarate transport + +[Term] +id: GO:0015140 +name: malate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle." [GOC:ai] +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +relationship: part_of GO:0071423 ! malate transmembrane transport + +[Term] +id: GO:0015141 +name: succinate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other." [ISBN:0198506732] +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +relationship: part_of GO:0071422 ! succinate transmembrane transport + +[Term] +id: GO:0015142 +name: tricarboxylic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups." [GOC:ai] +synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] +xref: Reactome:R-HSA-372449 "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]" +xref: Reactome:R-HSA-75849 "Transport of Citrate from Mitochondrial Matrix to cytosol" +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +relationship: part_of GO:0035674 ! tricarboxylic acid transmembrane transport + +[Term] +id: GO:0015143 +name: urate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals." [GOC:ai] +synonym: "uric acid transmembrane transporter activity" EXACT [] +xref: Reactome:R-HSA-2872497 "SLC17A3-2 transports cytosolic urate to extracellular region" +xref: Reactome:R-HSA-561253 "SLC22A12 exchanges extracellular urate for cytosolic LACT" +xref: Reactome:R-HSA-5625210 "Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:1901702 ! salt transmembrane transporter activity +relationship: part_of GO:0015747 ! urate transport + +[Term] +id: GO:0015144 +name: carbohydrate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901476 +def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +synonym: "carbohydrate transporter activity" RELATED [] +synonym: "sugar transporter" NARROW [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0034219 ! carbohydrate transmembrane transport + +[Term] +id: GO:0015145 +name: monosaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0051119 ! sugar transmembrane transporter activity +relationship: part_of GO:0015749 ! monosaccharide transmembrane transport + +[Term] +id: GO:0015146 +name: pentose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +relationship: part_of GO:0015750 ! pentose transmembrane transport + +[Term] +id: GO:0015147 +name: L-arabinose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity" NARROW [] +is_a: GO:0042900 ! arabinose transmembrane transporter activity + +[Term] +id: GO:0015148 +name: D-xylose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0015146 ! pentose transmembrane transporter activity +relationship: part_of GO:0015753 ! D-xylose transmembrane transport + +[Term] +id: GO:0015149 +name: hexose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" +xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +relationship: part_of GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015150 +name: fucose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015756 ! fucose transmembrane transport + +[Term] +id: GO:0015151 +name: alpha-glucoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration." [GOC:jl, GOC:mtg_transport, http://www.biochem.purdue.edu/, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0042947 ! glucoside transmembrane transporter activity +relationship: part_of GO:0000017 ! alpha-glucoside transport + +[Term] +id: GO:0015152 +name: glucose-6-phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015760 ! glucose-6-phosphate transport + +[Term] +id: GO:0015153 +name: rhamnose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015762 ! rhamnose transmembrane transport + +[Term] +id: GO:0015154 +name: disaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of disaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity +relationship: part_of GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015155 +name: lactose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0019189 +def: "Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "lactose permease activity" EXACT [] +synonym: "lactose/glucose efflux transporter activity" NARROW [] +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0015767 ! lactose transport + +[Term] +id: GO:0015156 +name: melibiose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0015769 ! melibiose transport + +[Term] +id: GO:0015157 +name: oligosaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oligosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +synonym: "endosomal oligosaccharide transporter" NARROW [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +relationship: part_of GO:0015772 ! oligosaccharide transport + +[Term] +id: GO:0015158 +name: raffinose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "raffinose permease" RELATED [] +is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity +relationship: part_of GO:0015773 ! raffinose transport + +[Term] +id: GO:0015159 +name: polysaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +relationship: part_of GO:0015774 ! polysaccharide transport + +[Term] +id: GO:0015160 +name: beta-glucan transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015159 ! polysaccharide transmembrane transporter activity +relationship: part_of GO:0015775 ! beta-glucan transport + +[Term] +id: GO:0015161 +name: capsular polysaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of capsular-polysaccharides from one side of a membrane to the other. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "capsule polysaccharide transporter activity" EXACT [] +is_a: GO:0015159 ! polysaccharide transmembrane transporter activity +relationship: part_of GO:0015776 ! capsular polysaccharide transport + +[Term] +id: GO:0015164 +name: glucuronoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "glucuronide transporter activity" EXACT [] +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015779 ! glucuronoside transport + +[Term] +id: GO:0015165 +name: pyrimidine nucleotide-sugar transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005338 ! nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport + +[Term] +id: GO:0015166 +name: polyol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol." [ISBN:0198506732] +synonym: "sugar/polyol channel activity" NARROW [] +xref: Reactome:R-HSA-429571 "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6" +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0015791 ! polyol transport + +[Term] +id: GO:0015167 +name: arabitol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms." [ISBN:0198506732] +synonym: "arabinitol transporter activity" EXACT [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015792 ! arabinitol transmembrane transport + +[Term] +id: GO:0015168 +name: glycerol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:ai] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015793 ! glycerol transport + +[Term] +id: GO:0015169 +name: glycerol-3-phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol." [GOC:ai] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015794 ! glycerol-3-phosphate transmembrane transport + +[Term] +id: GO:0015170 +name: propanediol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects." [GOC:ai] +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015799 ! propanediol transport + +[Term] +id: GO:0015171 +name: amino acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015359 +def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "amino acid permease activity" EXACT [] +synonym: "amino acid transporter activity" BROAD [] +synonym: "amino acid/choline transmembrane transporter activity" NARROW [] +synonym: "general amino acid permease activity" RELATED [] +synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] +xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes" +xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons" +xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol" +xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine" +xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine" +xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol" +xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake" +xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids" +xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids" +xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids" +xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids" +xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine" +xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids" +xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine" +xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine" +xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids" +xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol" +xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine" +xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine" +xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine" +xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine" +xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane" +xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane" +xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine" +xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids" +xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids" +xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids" +xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids" +xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids" +xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate" +xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane" +xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine" +xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu" +xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" +xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol" +xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol" +xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" +xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" +xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" +xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +relationship: part_of GO:0003333 ! amino acid transmembrane transport + +[Term] +id: GO:0015172 +name: acidic amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "acidic amino acid transporter activity" BROAD [] +xref: Reactome:R-HSA-372448 "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp" +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015800 ! acidic amino acid transport + +[Term] +id: GO:0015173 +name: aromatic amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "aromatic amino acid transporter activity" BROAD [] +synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] +synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015801 ! aromatic amino acid transport + +[Term] +id: GO:0015174 +name: basic amino acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005286 +alt_id: GO:0015326 +def: "Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "basic amino acid permease activity" EXACT [] +synonym: "basic amino acid transporter activity" BROAD [] +synonym: "cationic amino acid transmembrane transporter activity" RELATED [] +xref: Reactome:R-HSA-8932851 "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-8959781 "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix" +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:1990822 ! basic amino acid transmembrane transport + +[Term] +id: GO:0015175 +name: neutral amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "neutral amino acid transporter activity" BROAD [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015176 +name: obsolete holin +namespace: molecular_function +def: "OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases." [TC:1.A.38.-.-] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "holin" EXACT [] +is_obsolete: true +consider: GO:0019835 + +[Term] +id: GO:0015179 +name: L-amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-amino acid transporter activity" BROAD [] +xref: Reactome:R-HSA-212614 "Glutamine transport from astrocytes" +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:1902475 ! L-alpha-amino acid transmembrane transport + +[Term] +id: GO:0015180 +name: L-alanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid." [GOC:go_curators, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "L-alanine transporter activity" BROAD [] +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0022858 ! alanine transmembrane transporter activity +relationship: part_of GO:0015808 ! L-alanine transport + +[Term] +id: GO:0015181 +name: arginine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005288 +def: "Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "arginine permease activity" EXACT [] +synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] +synonym: "L-arginine transporter activity" NARROW [] +xref: RHEA:32143 +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity +relationship: part_of GO:1903826 ! arginine transmembrane transport + +[Term] +id: GO:0015182 +name: L-asparagine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid." [GOC:go_curators, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "asparagine/glutamine permease activity" NARROW [] +synonym: "L-asparagine transporter activity" BROAD [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0006867 ! asparagine transport + +[Term] +id: GO:0015183 +name: L-aspartate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "glutamate/aspartate porter activity" NARROW [] +synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] +synonym: "L-aspartate transporter activity" BROAD [] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015172 ! acidic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +relationship: part_of GO:0070778 ! L-aspartate transmembrane transport + +[Term] +id: GO:0015184 +name: L-cystine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-cystine from one side of a membrane to the other." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "cystine/diaminopimelate porter activity" NARROW [] +synonym: "L-cystine transporter activity" BROAD [] +xref: Reactome:R-HSA-5340130 "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol" +is_a: GO:0000099 ! sulfur amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:0015811 ! L-cystine transport + +[Term] +id: GO:0015185 +name: gamma-aminobutyric acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA)." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "4-aminobutanoate transporter activity" EXACT [] +synonym: "4-aminobutyrate transporter activity" EXACT [] +synonym: "betaine/GABA:sodium symporter activity" NARROW [] +synonym: "GABA transporter activity" EXACT [] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015812 ! gamma-aminobutyric acid transport + +[Term] +id: GO:0015186 +name: L-glutamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "asparagine/glutamine permease activity" NARROW [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0006868 ! glutamine transport + +[Term] +id: GO:0015187 +name: glycine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid." [GOC:ai] +synonym: "glycine betaine/proline porter activity" NARROW [] +synonym: "glycine transporter activity" BROAD [] +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015816 ! glycine transport + +[Term] +id: GO:0015188 +name: L-isoleucine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "isoleucine/valine:sodium symporter activity" NARROW [] +synonym: "L-isoleucine transporter activity" BROAD [] +synonym: "leucine/isoleucine/valine porter activity" NARROW [] +synonym: "leucine/valine/isoleucine permease activity" NARROW [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015658 ! branched-chain amino acid transmembrane transporter activity + +[Term] +id: GO:0015189 +name: L-lysine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005293 +def: "Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] +synonym: "L-lysine permease" RELATED [] +synonym: "lysine permease activity" RELATED [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:1903401 ! L-lysine transmembrane transport + +[Term] +id: GO:0015190 +name: L-leucine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-leucine transporter activity" BROAD [] +synonym: "leucine/isoleucine/valine porter activity" NARROW [] +synonym: "leucine/valine/isoleucine permease activity" NARROW [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015658 ! branched-chain amino acid transmembrane transporter activity + +[Term] +id: GO:0015191 +name: L-methionine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-methionine transporter activity" BROAD [] +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0043865 ! methionine transmembrane transporter activity + +[Term] +id: GO:0015192 +name: L-phenylalanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-phenylalanine permease activity" EXACT [] +synonym: "L-phenylalanine transporter activity" BROAD [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015823 ! phenylalanine transport + +[Term] +id: GO:0015193 +name: L-proline transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005296 +def: "Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "glycine betaine/proline porter activity" NARROW [] +synonym: "L-proline permease activity" RELATED [] +synonym: "L-proline transporter activity" BROAD [] +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] +xref: Reactome:R-HSA-8870354 "SLC36A4 transports extracellular L-Pro to the cytosol" +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0035524 ! proline transmembrane transport + +[Term] +id: GO:0015194 +name: L-serine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015511 +alt_id: GO:1905361 +def: "Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-serine permease activity" RELATED [] +synonym: "L-serine transporter activity" BROAD [] +synonym: "serine transporter activity" BROAD [] +synonym: "threonine/serine:sodium symporter activity" RELATED [] +xref: Reactome:R-HSA-8932980 "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane" +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0022889 ! serine transmembrane transporter activity +relationship: part_of GO:0015825 ! L-serine transport + +[Term] +id: GO:0015195 +name: L-threonine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015512 +def: "Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-threonine permease activity" RELATED [] +synonym: "L-threonine transporter activity" BROAD [] +synonym: "threonine/serine:sodium symporter activity" RELATED [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015826 ! threonine transport + +[Term] +id: GO:0015196 +name: L-tryptophan transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005299 +def: "Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-tryptophan permease activity" EXACT [] +synonym: "L-tryptophan transporter activity" BROAD [] +synonym: "valine/tyrosine/tryptophan permease activity" NARROW [] +xref: Reactome:R-HSA-8870352 "SLC36A4 transports L-Trp from extracellular region to cytosol" +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015827 ! tryptophan transport + +[Term] +id: GO:0015199 +name: amino-acid betaine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid." [GOC:ai] +synonym: "betaine transmembrane transporter activity" EXACT [] +synonym: "betaine/GABA:sodium symporter activity" NARROW [] +synonym: "glycine betaine/proline porter activity" NARROW [] +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:0015838 ! amino-acid betaine transport + +[Term] +id: GO:0015200 +name: methylammonium transmembrane transporter activity +namespace: molecular_function +def: "Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0005275 ! amine transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +relationship: part_of GO:0072489 ! methylammonium transmembrane transport + +[Term] +id: GO:0015203 +name: polyamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other." [GOC:ai] +synonym: "amine/amide/polyamine channel activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1902047 ! polyamine transmembrane transport + +[Term] +id: GO:0015204 +name: urea transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015287 +def: "Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2." [ISBN:0198506732] +synonym: "urea transporter activity" BROAD [] +xref: Reactome:R-HSA-444126 "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively" +xref: RHEA:32799 +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0071918 ! urea transmembrane transport + +[Term] +id: GO:0015205 +name: nucleobase transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015392 +def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015851 ! nucleobase transport + +[Term] +id: GO:0015207 +name: adenine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other." [GOC:go_curators] +xref: Reactome:R-HSA-163215 "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane" +xref: Reactome:R-HSA-5672027 "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane" +is_a: GO:0005345 ! purine nucleobase transmembrane transporter activity +relationship: part_of GO:0015853 ! adenine transport + +[Term] +id: GO:0015208 +name: guanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other." [GOC:go_curators] +is_a: GO:0005345 ! purine nucleobase transmembrane transporter activity +relationship: part_of GO:1903716 ! guanine transmembrane transport + +[Term] +id: GO:0015209 +name: cytosine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other." [GOC:go_curators] +is_a: GO:0005350 ! pyrimidine nucleobase transmembrane transporter activity +relationship: part_of GO:0015856 ! cytosine transport + +[Term] +id: GO:0015210 +name: uracil transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other." [GOC:go_curators] +synonym: "uracil/uridine permease activity" RELATED [] +is_a: GO:0005350 ! pyrimidine nucleobase transmembrane transporter activity +relationship: part_of GO:1903791 ! uracil transmembrane transport + +[Term] +id: GO:0015211 +name: purine nucleoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +relationship: part_of GO:0015860 ! purine nucleoside transmembrane transport + +[Term] +id: GO:0015212 +name: cytidine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other." [GOC:go_curators] +is_a: GO:0015214 ! pyrimidine nucleoside transmembrane transporter activity +relationship: part_of GO:0015861 ! cytidine transport + +[Term] +id: GO:0015213 +name: uridine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other." [GOC:go_curators] +synonym: "uracil/uridine permease activity" NARROW [] +is_a: GO:0015214 ! pyrimidine nucleoside transmembrane transporter activity +relationship: part_of GO:0015862 ! uridine transport + +[Term] +id: GO:0015214 +name: pyrimidine nucleoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other." [GOC:ai] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +relationship: part_of GO:0072531 ! pyrimidine-containing compound transmembrane transport + +[Term] +id: GO:0015215 +name: nucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other." [ISBN:0198506732] +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity +relationship: part_of GO:1901679 ! nucleotide transmembrane transport + +[Term] +id: GO:0015216 +name: purine nucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +relationship: part_of GO:0015865 ! purine nucleotide transport + +[Term] +id: GO:0015217 +name: ADP transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +relationship: part_of GO:0015866 ! ADP transport + +[Term] +id: GO:0015218 +name: pyrimidine nucleotide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +relationship: part_of GO:0006864 ! pyrimidine nucleotide transport + +[Term] +id: GO:0015219 +name: obsolete protein-DNA complex transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other." [GOC:ai] +comment: This term was obsoleted because there is no experimental evidence that this function exists. +synonym: "DNA-protein complex transmembrane transporter activity" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17005 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0015220 +name: choline transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005306 +def: "Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:ai] +synonym: "amino acid/choline transmembrane transporter activity" NARROW [] +synonym: "choline permease activity" EXACT [] +xref: Reactome:R-HSA-429594 "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-444433 "Cho transports from the extracellular space to the cytosol" +xref: Reactome:R-HSA-5658483 "Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-6797956 "SLC44A1 transports Cho from cytosol to mitochondrial matrix" +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +relationship: part_of GO:0015871 ! choline transport + +[Term] +id: GO:0015221 +name: lipopolysaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "LPS transmembrane transporter activity" EXACT [] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015920 ! lipopolysaccharide transport + +[Term] +id: GO:0015223 +name: obsolete vitamin or cofactor transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "vitamin or cofactor transporter activity" EXACT [] +synonym: "vitamin/cofactor transporter activity" EXACT [] +is_obsolete: true +consider: GO:0051184 +consider: GO:0090482 + +[Term] +id: GO:0015224 +name: biopterin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme." [ISBN:0198506732] +synonym: "biopterin transporter activity" RELATED [] +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +relationship: part_of GO:0015877 ! biopterin transport + +[Term] +id: GO:0015225 +name: biotin transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901603 +def: "Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:ai] +synonym: "biotin transporter activity" RELATED [] +synonym: "vitamin B7 transporter activity" RELATED [] +synonym: "vitamin H transporter activity" RELATED [] +xref: RHEA:28458 +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0015878 ! biotin transport +created_by: al +creation_date: 2012-11-08T14:18:56Z + +[Term] +id: GO:0015226 +name: carnitine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:ai] +synonym: "vitamin Bt transporter activity" EXACT [] +xref: Reactome:R-HSA-164967 "Unknown carnitine exporter transports CAR from the cytosol to the extracellular space" +xref: Reactome:R-HSA-165026 "OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol" +xref: Reactome:R-HSA-549297 "SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5625674 "Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol" +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:1902603 ! carnitine transmembrane transport + +[Term] +id: GO:0015227 +name: acyl carnitine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane." [GOC:ai] +synonym: "acylcarnitine transporter activity" BROAD [] +xref: Reactome:R-HSA-200424 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane" +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +relationship: part_of GO:1902616 ! acyl carnitine transmembrane transport + +[Term] +id: GO:0015228 +name: coenzyme A transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:ai] +synonym: "coenzyme A transporter activity" BROAD [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:0071077 ! adenosine 3',5'-bisphosphate transmembrane transporter activity +relationship: part_of GO:0035349 ! coenzyme A transmembrane transport + +[Term] +id: GO:0015229 +name: L-ascorbic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species." [ISBN:0198506732] +synonym: "L-ascorbate transporter activity" EXACT [] +synonym: "vitamin C transporter activity" EXACT [] +xref: Reactome:R-HSA-198870 "SVCT1/2 cotransports extracellular VitC and 2Na+ to cytosol" +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0015882 ! L-ascorbic acid transmembrane transport + +[Term] +id: GO:0015230 +name: FAD transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005472 +def: "Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form." [ISBN:0198506732] +synonym: "FAD carrier activity" RELATED [] +synonym: "FAD transporter activity" BROAD [] +synonym: "flavin adenine dinucleotide carrier activity" RELATED [] +synonym: "flavin adenine dinucleotide transmembrane transporter activity" EXACT [] +synonym: "flavin-adenine dinucleotide carrier activity" RELATED [] +synonym: "flavin-adenine dinucleotide transmembrane transporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +relationship: part_of GO:0035350 ! FAD transmembrane transport + +[Term] +id: GO:0015231 +name: 5-formyltetrahydrofolate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other." [GOC:ai] +synonym: "5-formyltetrahydrofolate transporter activity" EXACT [] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:0015885 ! 5-formyltetrahydrofolate transport + +[Term] +id: GO:0015232 +name: heme transporter activity +namespace: molecular_function +def: "Enables the directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells." [GOC:ai] +synonym: "haem transporter activity" EXACT [] +xref: Reactome:R-HSA-1369065 "ABCB6 transports porphyrin from cytosol to mitchondrial matrix" +xref: Reactome:R-HSA-382560 "ABC7, mABC1 and mABC2 mediate heme transport" +xref: Reactome:R-HSA-5683355 "Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix" +xref: Reactome:R-HSA-917870 "SLC46A1 transports FeHM from extracellular region to cytosol" +xref: Reactome:R-HSA-917892 "FLVCR transports heme from cytosol to extracellular region" +xref: Reactome:R-HSA-917979 "ABCG2 dimer transports heme from cytosol to extracellular region" +is_a: GO:0051184 ! cofactor transmembrane transporter activity +relationship: part_of GO:0015886 ! heme transport + +[Term] +id: GO:0015233 +name: pantothenate transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544] +synonym: "pantothenate transporter activity" BROAD [GOC:mah] +synonym: "vitamin B5 transmembrane transporter activity" EXACT [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0015887 ! pantothenate transmembrane transport + +[Term] +id: GO:0015234 +name: thiamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015402 +alt_id: GO:0015403 +def: "Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "thiamin permease activity" EXACT [] +synonym: "thiamin transmembrane transporter activity" EXACT [] +synonym: "thiamin uptake transporter activity" RELATED [] +synonym: "thiamine permease activity" EXACT [] +synonym: "thiamine uptake transmembrane transporter activity" RELATED [] +synonym: "vitamin B1 transporter activity" EXACT [] +xref: Reactome:R-HSA-199626 "SLC19A2/3 transport extracellular THMN to cytosol" +is_a: GO:0090482 ! vitamin transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0071934 ! thiamine transmembrane transport + +[Term] +id: GO:0015240 +name: amiloride transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic." [ISBN:0198506732] +synonym: "amiloride transporter activity" RELATED [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0015898 ! amiloride transport + +[Term] +id: GO:0015243 +name: cycloheximide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes." [ISBN:0198506732] +synonym: "cycloheximide transporter activity" RELATED [] +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0015901 ! cycloheximide transport + +[Term] +id: GO:0015244 +name: fluconazole transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections." [GOC:curators] +synonym: "fluconazole transporter activity" RELATED [] +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +relationship: part_of GO:0015903 ! fluconazole transport + +[Term] +id: GO:0015245 +name: fatty acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015246 +def: "Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732] +synonym: "fatty acid transporter activity" RELATED [] +synonym: "fatty acyl transporter activity" EXACT [] +synonym: "fatty-acyl group transporter activity" BROAD [] +synonym: "peroxisomal fatty acyl transporter" NARROW [] +xref: Reactome:R-HSA-5627891 "Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol" +xref: Reactome:R-HSA-879585 "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol" +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015908 ! fatty acid transport + +[Term] +id: GO:0015247 +name: aminophospholipid flippase activity +namespace: molecular_function +def: "Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group." [GOC:pg] +synonym: "aminophospholipid transmembrane transporter activity" RELATED [] +synonym: "aminophospholipid transporter activity" RELATED [] +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0140327 ! flippase activity +relationship: part_of GO:0140331 ! aminophospholipid translocation + +[Term] +id: GO:0015248 +name: sterol transporter activity +namespace: molecular_function +def: "Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:ai] +xref: Reactome:R-HSA-265783 "ABCG5:ABCG8 transports sterols from cytosol to extracellular region" +xref: Reactome:R-HSA-5250531 "ARV1 transports CHOL from ER membrane to plasma membrane" +xref: Reactome:R-HSA-5679101 "Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region" +xref: Reactome:R-HSA-5679145 "Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region" +xref: Reactome:R-HSA-8867667 "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane" +xref: Reactome:R-HSA-8868402 "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane" +is_a: GO:0005319 ! lipid transporter activity +relationship: part_of GO:0015918 ! sterol transport + +[Term] +id: GO:0015250 +name: water channel activity +namespace: molecular_function +def: "Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] +synonym: "aquaporin" NARROW [] +xref: Reactome:R-HSA-432010 "Aquaporin-1 passively transports water into cell" +xref: Reactome:R-HSA-432054 "Aquaporin-1 passively transports water out of cell" +xref: Reactome:R-HSA-432065 "p-S256-Aquaporin-2 passively transports water into cell" +xref: Reactome:R-HSA-432067 "Aquaporin-4 passively transports water out of cell" +xref: Reactome:R-HSA-445714 "Aquaporin-3 passively transports water out of cell" +xref: Reactome:R-HSA-507868 "Aquaporins passively transport water into cells" +xref: Reactome:R-HSA-507870 "Aquaporins passively transport water out of cells" +is_a: GO:0005372 ! water transmembrane transporter activity +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0015251 +name: ammonium channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0008519 ! ammonium transmembrane transporter activity + +[Term] +id: GO:0015252 +name: proton channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +synonym: "hydrogen ion channel activity" EXACT [] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0015078 ! proton transmembrane transporter activity + +[Term] +id: GO:0015253 +name: obsolete sugar/polyol channel activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents two molecular functions. +synonym: "sugar/polyol channel activity" EXACT [] +is_obsolete: true +consider: GO:0015166 +consider: GO:0051119 + +[Term] +id: GO:0015254 +name: glycerol channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-432049 "Aquaporin-9 passively transports glycerol into cell" +xref: Reactome:R-HSA-432074 "Aquaporin-7 passively transports glycerol out of cell" +xref: Reactome:R-HSA-507869 "Aquaporins passively transport glycerol into cells" +xref: Reactome:R-HSA-507871 "Aquaporins passively transport glycerol out of cells" +is_a: GO:0015168 ! glycerol transmembrane transporter activity +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0015255 +name: propanediol channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] +is_a: GO:0015170 ! propanediol transmembrane transporter activity +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0015256 +name: obsolete monocarboxylate channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "monocarboxylate channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015257 +name: obsolete organic anion channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "organic anion channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015258 +name: obsolete gluconate channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "gluconate channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015259 +name: obsolete glutamate channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "glutamate channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015260 +name: obsolete isethionate channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "isethionate channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015261 +name: obsolete lactate channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "lactate channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015262 +name: obsolete taurine channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because this solute is transported by an active transporter rather than a channel. +synonym: "taurine channel activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015263 +name: obsolete amine/amide/polyamine channel activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents three molecular functions. +synonym: "amine/amide/polyamine channel activity" EXACT [] +is_obsolete: true +consider: GO:0005275 +consider: GO:0015203 +consider: GO:0042887 + +[Term] +id: GO:0015264 +name: methylammonium channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2." [GOC:mtg_transport, GOC:pr] +is_a: GO:0015200 ! methylammonium transmembrane transporter activity +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0015265 +name: urea channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] +xref: Reactome:R-HSA-507873 "Aquaporins passively transport urea out of cells" +xref: Reactome:R-HSA-507875 "Aquaporins passively transport urea into cells" +is_a: GO:0015204 ! urea transmembrane transporter activity +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0015267 +name: channel activity +namespace: molecular_function +alt_id: GO:0015249 +alt_id: GO:0015268 +alt_id: GO:0022838 +def: "Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules." [GOC:mtg_transport, ISBN:0815340729, TC:1.-.-.-.-] +synonym: "alpha-type channel activity" RELATED [] +synonym: "channel-forming toxin activity" RELATED [] +synonym: "channel/pore class transporter activity" EXACT [] +synonym: "nonselective channel activity" EXACT [] +synonym: "pore activity" BROAD [] +synonym: "pore class transporter activity" RELATED [] +synonym: "substrate-specific channel activity" RELATED [] +xref: Reactome:R-HSA-3779381 "H2O2 diffuses from the mitochondrial matrix to the cytosol" +xref: Reactome:R-HSA-8953430 "PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix" +xref: TC:1 +is_a: GO:0022803 ! passive transmembrane transporter activity + +[Term] +id: GO:0015269 +name: calcium-activated potassium channel activity +namespace: molecular_function +def: "Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport] +is_a: GO:0005227 ! calcium activated cation channel activity +is_a: GO:0005267 ! potassium channel activity + +[Term] +id: GO:0015271 +name: outward rectifier potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force." [GOC:mah] +is_a: GO:0005249 ! voltage-gated potassium channel activity + +[Term] +id: GO:0015272 +name: ATP-activated inward rectifier potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force." [GOC:cb, GOC:mah] +xref: Reactome:R-HSA-5683209 "Activating ABCC8 mutants cause hyperglycemia in permanent neonatal diabetes mellitus (PNDM) and transient neonatal DM (TNDM)." +is_a: GO:0005242 ! inward rectifier potassium channel activity + +[Term] +id: GO:0015274 +name: organellar voltage-gated chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "organellar voltage gated chloride channel activity" EXACT [] +synonym: "organellar voltage-dependent chloride channel activity" EXACT [] +is_a: GO:0005247 ! voltage-gated chloride channel activity + +[Term] +id: GO:0015275 +name: stretch-activated, cation-selective, calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching." [GOC:mtg_transport] +is_a: GO:0005262 ! calcium channel activity +is_a: GO:0140135 ! mechanosensitive cation channel activity + +[Term] +id: GO:0015276 +name: ligand-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +synonym: "ionotropic receptor activity" NARROW [GOC:bf, GOC:sart] +xref: Reactome:R-HSA-451310 "Activation of Edited Kainate receptors" +xref: Reactome:R-HSA-451311 "Activation of Ca-permeable Kainate receptors" +xref: Reactome:R-HSA-622325 "Activation of highly sodium permeable nicotinic acetylcholine receptors" +xref: Reactome:R-HSA-622326 "Activation of highly calcium permeable nicotinic acetylcholine receptors" +xref: Reactome:R-HSA-629595 "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors" +is_a: GO:0005216 ! ion channel activity +is_a: GO:0022834 ! ligand-gated channel activity + +[Term] +id: GO:0015277 +name: kainate selective glutamate receptor activity +namespace: molecular_function +def: "An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist." [GOC:mah, PMID:10049997, PMID:8804111] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. +is_a: GO:0004970 ! ionotropic glutamate receptor activity +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0005272 ! sodium channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0015278 +name: calcium-release channel activity +namespace: molecular_function +alt_id: GO:0005218 +def: "Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mah] +synonym: "intracellular ligand-gated calcium channel activity" RELATED [GO:0015278] +is_a: GO:0005217 ! intracellular ligand-gated ion channel activity +is_a: GO:0099604 ! ligand-gated calcium channel activity +relationship: part_of GO:0051209 ! release of sequestered calcium ion into cytosol + +[Term] +id: GO:0015279 +name: store-operated calcium channel activity +namespace: molecular_function +def: "A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores." [GOC:dph, GOC:tb, PMID:15788710] +xref: Reactome:R-HSA-434798 "CRAC translocates calcium from the extracellular region to the cytosol" +is_a: GO:0005262 ! calcium channel activity + +[Term] +id: GO:0015280 +name: ligand-gated sodium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mah] +synonym: "acid-sensing ion channel activity" NARROW [GOC:fj] +synonym: "amiloride-sensitive sodium channel activity" NARROW [GOC:fj] +synonym: "ASIC activity" NARROW [GOC:fj] +synonym: "epithelial sodium channel" NARROW [GOC:fj] +xref: Reactome:R-HSA-2672334 "SCNN channels transport extracellular Na+ to cytosol" +is_a: GO:0005272 ! sodium channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity + +[Term] +id: GO:0015282 +name: obsolete NADPH oxidase-associated cytochrome b558 hydrogen channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because it describes a gene product rather than a function. +synonym: "NADPH oxidase-associated cytochrome b558 hydrogen channel activity" EXACT [] +synonym: "NADPH oxidase-associated cytochrome b558 proton channel" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015283 +name: obsolete apoptogenic cytochrome c release channel activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because it represents a gene product. +synonym: "apoptogenic cytochrome c release channel activity" EXACT [] +synonym: "Bcl-2" NARROW [] +is_obsolete: true + +[Term] +id: GO:0015284 +name: fructose uniporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in)." [TC:2.A.1.1.13] +is_a: GO:0005353 ! fructose transmembrane transporter activity +is_a: GO:0008516 ! hexose uniporter activity + +[Term] +id: GO:0015288 +name: porin activity +namespace: molecular_function +def: "Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820, TC:1.B.1.-.-] +synonym: "outer membrane exporter porin" NARROW [] +synonym: "porin" EXACT [] +xref: Wikipedia:Porin_(protein) +is_a: GO:0022829 ! wide pore channel activity + +[Term] +id: GO:0015289 +name: obsolete pore-forming toxin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell." [PMID:10839820] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "pore-forming toxin activity" EXACT [] +is_obsolete: true +consider: GO:0005198 +consider: GO:0009405 +consider: GO:0046930 +consider: GO:0046931 +consider: GO:0090729 + +[Term] +id: GO:0015291 +name: secondary active transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015290 +alt_id: GO:0015353 +alt_id: GO:0015404 +alt_id: GO:0015570 +def: "Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729, PMID:10839820] +synonym: "active transporter" BROAD [] +synonym: "coupled carrier" EXACT [] +synonym: "electrochemical potential-driven transporter activity" EXACT [] +synonym: "energizer of outer membrane receptor-mediated transport activity" NARROW [] +synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] +synonym: "heavy metal ion porter activity" NARROW [] +synonym: "ion-gradient-driven energizer activity" NARROW [] +synonym: "multidrug endosomal transmembrane transporter activity" NARROW [] +synonym: "nitrite/nitrate porter activity" NARROW [] +synonym: "porter activity" EXACT [] +synonym: "porters" EXACT [] +synonym: "secondary carrier-type facilitators" EXACT [] +xref: Reactome:R-HSA-199216 "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix" +xref: TC:2.A +is_a: GO:0022804 ! active transmembrane transporter activity + +[Term] +id: GO:0015292 +name: uniporter activity +namespace: molecular_function +def: "Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] +synonym: "facilitated diffusion carrier" EXACT [] +synonym: "single-species transporter activity" EXACT [] +synonym: "uniport" RELATED [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0015293 +name: symporter activity +namespace: molecular_function +def: "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] +synonym: "cotransporter activity" BROAD [] +synonym: "porter activity" BROAD [] +synonym: "symport" RELATED [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0015294 +name: solute:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in)." [GOC:ai] +is_a: GO:0015293 ! symporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity + +[Term] +id: GO:0015295 +name: solute:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in)." [GOC:ai] +synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] +synonym: "high affinity metal ion uptake transporter activity" NARROW [] +synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] +synonym: "low affinity metal ion uptake transporter activity" NARROW [] +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] +synonym: "solute:hydrogen symporter activity" EXACT [] +is_a: GO:0015078 ! proton transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0015296 +name: anion:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in)." [TC:2.A.1.14.-] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0015297 +name: antiporter activity +namespace: molecular_function +alt_id: GO:0015300 +alt_id: GO:0099516 +def: "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out)." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] +synonym: "antiport" RELATED [] +synonym: "countertransporter activity" EXACT [] +synonym: "exchange transporter activity" EXACT [] +synonym: "exchanger" BROAD [] +synonym: "ion antiporter activity" NARROW [] +synonym: "porter" BROAD [] +synonym: "solute:solute antiporter activity" EXACT [] +synonym: "solute:solute exchange" RELATED [] +xref: Reactome:R-HSA-2730692 "CLCN4/5/6 exchange Cl- for H+" +xref: Reactome:R-HSA-2730959 "CLCN7:OSTM1 exchanges Cl- for H+" +xref: Reactome:R-HSA-2731002 "CLCN3 exchanges Cl- for H+" +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0015298 +name: solute:cation antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out)." [GOC:ai] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015297 ! antiporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015299 +name: solute:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out)." [GOC:ai] +synonym: "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity" NARROW [] +synonym: "solute:hydrogen antiporter activity" EXACT [] +is_a: GO:0015078 ! proton transmembrane transporter activity +is_a: GO:0015298 ! solute:cation antiporter activity + +[Term] +id: GO:0015301 +name: anion:anion antiporter activity +namespace: molecular_function +alt_id: GO:0015380 +alt_id: GO:0015384 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out)." [GOC:ai, GOC:mtg_transport] +synonym: "anion exchanger activity" EXACT [] +synonym: "bicarbonate:chloride antiporter" NARROW [] +xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids" +is_a: GO:0140323 ! solute:anion antiporter activity + +[Term] +id: GO:0015303 +name: obsolete galactose, glucose uniporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in)." [TC:2.A.1.1.6] +comment: This term was made obsolete because it represents two molecular functions. +synonym: "galactose, glucose uniporter activity" EXACT [] +is_obsolete: true +consider: GO:0015304 +consider: GO:0050782 + +[Term] +id: GO:0015304 +name: glucose uniporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in)." [TC:2.A.1.1.12, TC:2.A.1.1.4, TC:2.A.1.1.6] +synonym: "galactose, glucose uniporter activity" NARROW [] +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0008516 ! hexose uniporter activity + +[Term] +id: GO:0015305 +name: obsolete lactose, galactose:proton symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in)." [TC:2.A.1.1.9] +comment: This term was made obsolete because it represents two molecular functions. +synonym: "lactose, galactose:hydrogen symporter activity" EXACT [] +synonym: "lactose, galactose:proton symporter activity" EXACT [] +synonym: "lactose,galactose:proton symporter activity" EXACT [] +is_obsolete: true +consider: GO:0015517 +consider: GO:0015528 + +[Term] +id: GO:0015306 +name: sialate:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in)." [TC:2.A.1.14.10] +synonym: "cation/sialate symporter activity" EXACT [] +synonym: "cation:sialate symporter activity" EXACT [] +synonym: "sialate transporter activity" BROAD [] +synonym: "sialate/cation symporter activity" EXACT [] +is_a: GO:0015136 ! sialic acid transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0015307 +name: obsolete drug:proton antiporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out)." [TC:2.A.1.2.-, TC:2.A.1.3.-] +comment: This term was obsoleted because it is not possible to state that every case of transmembrane transport for a specific chemical constitutes a drug transport. +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] +synonym: "drug:hydrogen antiporter activity" EXACT [] +xref: Reactome:R-HSA-434650 "MATEs mediate extrusion of xenobiotics" +xref: Reactome:R-HSA-5625574 "Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+" +xref: Reactome:R-HSA-597628 "SLC22A18 exchanges extracellular organic cations for cytosolic H+" +is_obsolete: true + +[Term] +id: GO:0015308 +name: amiloride:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out)." [TC:2.A.1.2.1] +synonym: "amiloride:hydrogen antiporter activity" EXACT [] +is_a: GO:0015240 ! amiloride transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0015309 +name: cycloheximide:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out)." [TC:2.A.1.2.2] +synonym: "cycloheximide:hydrogen antiporter activity" EXACT [] +is_a: GO:0015243 ! cycloheximide transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity + +[Term] +id: GO:0015310 +name: benomyl:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out)." [TC:2.A.1.2.6] +synonym: "benomyl:hydrogen antiporter activity" EXACT [] +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:1901479 ! benomyl transmembrane transporter activity + +[Term] +id: GO:0015311 +name: monoamine:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out)." [TC:2.A.1.2.11, TC:2.A.1.2.12] +synonym: "monoamine:hydrogen antiporter activity" EXACT [] +is_a: GO:0008504 ! monoamine transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity + +[Term] +id: GO:0015312 +name: polyamine:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out)." [TC:2.A.1.2.16] +synonym: "polyamine:hydrogen antiporter activity" EXACT [] +is_a: GO:0015203 ! polyamine transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity + +[Term] +id: GO:0015313 +name: fluconazole:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out)." [TC:2.A.1.2.17] +synonym: "fluconazole:hydrogen antiporter activity" EXACT [] +is_a: GO:0015244 ! fluconazole transmembrane transporter activity +is_a: GO:0045119 ! azole:proton antiporter activity + +[Term] +id: GO:0015314 +name: aminotriazole:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out)." [TC:2.A.1.3.1] +synonym: "aminotriazole:hydrogen antiporter activity" EXACT [] +is_a: GO:0005451 ! monovalent cation:proton antiporter activity +is_a: GO:0045119 ! azole:proton antiporter activity +is_a: GO:1901478 ! aminotriazole transmembrane transporter activity + +[Term] +id: GO:0015315 +name: organophosphate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.-] +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity +is_a: GO:0140323 ! solute:anion antiporter activity + +[Term] +id: GO:0015316 +name: obsolete nitrite/nitrate porter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "nitrite/nitrate porter activity" EXACT [] +is_obsolete: true +consider: GO:0015112 +consider: GO:0015113 +consider: GO:0015291 + +[Term] +id: GO:0015317 +name: phosphate:proton symporter activity +namespace: molecular_function +alt_id: GO:0015320 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in)." [TC:2.A.1.9.-] +synonym: "phosphate ion carrier activity" EXACT [] +synonym: "phosphate:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14221 xsd:anyURI + +[Term] +id: GO:0015318 +name: inorganic molecular entity transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729] +subset: gocheck_do_not_annotate +synonym: "inorganic solute uptake transmembrane transporter activity" EXACT [] +synonym: "inorganic uptake permease activity" EXACT [] +is_a: GO:0022857 ! transmembrane transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14372 xsd:anyURI + +[Term] +id: GO:0015319 +name: sodium:inorganic phosphate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in)." [TC:2.A.1.14.6] +is_a: GO:0005315 ! inorganic phosphate transmembrane transporter activity +is_a: GO:0005436 ! sodium:phosphate symporter activity + +[Term] +id: GO:0015322 +name: secondary active oligopeptide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport] +synonym: "oligopeptide porter activity" RELATED [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity + +[Term] +id: GO:0015323 +name: obsolete type V protein secretor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because it does not accurately reflect the function of the proteins involved. +synonym: "type V protein secretor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015324 +name: peptide-acetyl-CoA secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "peptide-acetyl-CoA transporter activity" RELATED [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0015325 +name: acetyl-CoA:CoA antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out)." [TC:2.A.1.25.1] +is_a: GO:0008521 ! acetyl-CoA transmembrane transporter activity +is_a: GO:0015228 ! coenzyme A transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015324 ! peptide-acetyl-CoA secondary active transmembrane transporter activity + +[Term] +id: GO:0015327 +name: cystine:glutamate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out)." [TC:2.A.3.8.5] +is_a: GO:0005313 ! L-glutamate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015328 ! cystine secondary active transmembrane transporter activity + +[Term] +id: GO:0015328 +name: cystine secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "cystine porter activity" RELATED [] +synonym: "cystinosin" NARROW [] +synonym: "lysosomal cystine transporter" NARROW [] +is_a: GO:0005294 ! neutral L-amino acid secondary active transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:1901680 ! sulfur-containing amino acid secondary active transmembrane transporter activity + +[Term] +id: GO:0015330 +name: high-affinity glutamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity glutamine permease activity" RELATED [] +synonym: "high affinity glutamine transmembrane transporter activity" EXACT [] +is_a: GO:0005287 ! high-affinity basic amino acid transmembrane transporter activity +is_a: GO:0015186 ! L-glutamine transmembrane transporter activity + +[Term] +id: GO:0015331 +name: obsolete asparagine/glutamine permease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "asparagine/glutamine permease activity" EXACT [] +is_obsolete: true +consider: GO:0015182 +consider: GO:0015186 +consider: GO:0022857 + +[Term] +id: GO:0015332 +name: obsolete leucine/valine/isoleucine permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "leucine/valine/isoleucine permease activity" EXACT [] +is_obsolete: true +consider: GO:0005304 +consider: GO:0015188 +consider: GO:0015190 +consider: GO:0022857 + +[Term] +id: GO:0015333 +name: peptide:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement." [GOC:mtg_transport, TC:2.A.17.-.-] +synonym: "peptide:hydrogen symporter activity" EXACT [] +xref: Reactome:R-HSA-427998 "Proton-coupled di- and tri-peptide cotransport" +xref: Reactome:R-HSA-428007 "Proton-coupled histidine and di-peptide cotransport" +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity + +[Term] +id: GO:0015334 +name: high-affinity oligopeptide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:mtg_transport] +synonym: "high affinity oligopeptide transporter activity" EXACT [] +synonym: "high-affinity oligopeptide transporter activity" RELATED [] +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity + +[Term] +id: GO:0015335 +name: obsolete heavy metal ion:hydrogen symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+." [TC:2.A.55.2.1, TC:2.A.55.2.2] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "heavy metal ion:hydrogen symporter activity" EXACT [] +synonym: "heavy metal ion:proton symporter activity" EXACT [] +is_obsolete: true +consider: GO:0015295 +consider: GO:0046873 + +[Term] +id: GO:0015336 +name: obsolete high affinity metal ion uptake transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+." [TC:2.A.55.1.1] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "high affinity metal ion uptake transporter activity" EXACT [] +is_obsolete: true +consider: GO:0015295 +consider: GO:0046873 + +[Term] +id: GO:0015337 +name: obsolete low affinity metal ion uptake transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+." [TC:2.A.55.1.2] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "low affinity metal ion uptake transporter activity" EXACT [] +is_obsolete: true +consider: GO:0015295 +consider: GO:0046873 + +[Term] +id: GO:0015339 +name: obsolete cobalt, zinc uptake permease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport." [TC:2.A.4.2.1] +comment: This term was made obsolete because it represents more than one molecular function. +synonym: "cobalt, zinc uptake permease activity" EXACT [] +is_obsolete: true +consider: GO:0005385 +consider: GO:0015087 + +[Term] +id: GO:0015340 +name: obsolete zinc, cadmium uptake permease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport." [TC:2.A.4.2.2] +comment: This term was made obsolete because it represents more than one molecular function. +synonym: "zinc, cadmium uptake permease activity" EXACT [] +is_obsolete: true +consider: GO:0005385 +consider: GO:0015086 + +[Term] +id: GO:0015341 +name: zinc efflux active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.4.1.4, TC:2.A.4.2.3] +synonym: "zinc efflux permease activity" BROAD [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +is_a: GO:0022883 ! zinc efflux transmembrane transporter activity + +[Term] +id: GO:0015342 +name: obsolete zinc, iron permease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force." [TC:2.A.5.-.-] +comment: This term was made obsolete because it represents more than one molecular function. +synonym: "zinc, iron permease activity" EXACT [] +is_obsolete: true +consider: GO:0005381 +consider: GO:0005385 + +[Term] +id: GO:0015343 +name: siderophore transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015236 +alt_id: GO:0015237 +alt_id: GO:0042927 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in)." [TC:2.A.1.16.-] +synonym: "iron-siderophore transporter activity" EXACT [] +synonym: "siderochrome transporter activity" NARROW [] +synonym: "siderochrome-iron transporter activity" NARROW [] +synonym: "siderophore transporter activity" RELATED [] +synonym: "siderophore-iron transmembrane transporter activity" RELATED [] +synonym: "siderophore-iron transporter activity" RELATED [] +xref: Reactome:R-HSA-1222597 "Loaded mycobactin gets imported" +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0044718 ! siderophore transmembrane transport + +[Term] +id: GO:0015344 +name: siderophore uptake transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in)." [TC:2.A.1.16.1] +synonym: "ferrioxamine uptake transmembrane transporter activity" RELATED [] +synonym: "siderochrome-iron (ferrioxamine) uptake transporter" NARROW [] +synonym: "siderophore-iron uptake transmembrane transporter activity" RELATED [] +is_a: GO:0015343 ! siderophore transmembrane transporter activity + +[Term] +id: GO:0015345 +name: ferric enterobactin:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in)." [TC:2.A.1.16.2] +synonym: "ferric enterobactin:hydrogen symporter activity" EXACT [] +synonym: "ferric-enterobactin:proton symporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015603 ! iron chelate transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity + +[Term] +id: GO:0015346 +name: ferric triacetylfusarinine C:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in)." [TC:2.A.1.16.3] +synonym: "ferric triacetylfusarinine C:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015343 ! siderophore transmembrane transporter activity +is_a: GO:0015621 ! ferric triacetylfusarinine C transmembrane transporter activity +relationship: part_of GO:0015686 ! ferric triacetylfusarinine C import into cell + +[Term] +id: GO:0015347 +name: sodium-independent organic anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner." [GOC:go_curators] +xref: Reactome:R-HSA-561059 "OAT2 and OAT4 mediate transport of sulphate conjugates" +xref: Reactome:R-HSA-879562 "SLCO2B1 has a narrow substrate specificity" +xref: Reactome:R-HSA-879584 "SLCO3A1 isoform 1 has abroad substrate specificity" +xref: Reactome:R-HSA-879594 "SLCO4C1 mediates the transport of digoxin" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015348 +name: obsolete prostaglandin/thromboxane transporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "prostaglandin/thromboxane transporter activity" EXACT [] +is_obsolete: true +consider: GO:0008028 +consider: GO:0015132 + +[Term] +id: GO:0015349 +name: thyroid hormone transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine." [GOC:ai] +xref: Reactome:R-HSA-5661195 "Defective SLCO1B1 does not transport T3,T4 from extracellular region to cytosol" +xref: Reactome:R-HSA-879575 "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol" +xref: Reactome:R-HSA-9631987 "SLCO1B1 transports T3,T4 from extracellular region to cytosol" +is_a: GO:0015291 ! secondary active transmembrane transporter activity +relationship: part_of GO:0070327 ! thyroid hormone transport + +[Term] +id: GO:0015350 +name: methotrexate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase." [GOC:ai] +synonym: "methotrexate transporter activity" RELATED [] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0051958 ! methotrexate transport + +[Term] +id: GO:0015351 +name: bilirubin secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] +synonym: "bilirubin porter activity" RELATED [] +synonym: "bilitranslocase" NARROW [] +is_a: GO:0015127 ! bilirubin transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015352 +name: obsolete secondary active sterol transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport] +comment: This term was obsoleted because there is no evidence that this function exists. +synonym: "sterol porter activity" RELATED [] +is_obsolete: true + +[Term] +id: GO:0015355 +name: secondary active monocarboxylate transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism." [GOC:bf, GOC:jl] +synonym: "monocarboxylate porter activity" RELATED [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015356 +name: obsolete monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" EXACT [] +is_obsolete: true +consider: GO:0015129 +consider: GO:0015130 +consider: GO:0015562 +consider: GO:0050833 + +[Term] +id: GO:0015358 +name: obsolete amino acid/choline transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "amino acid/choline transmembrane transporter activity" EXACT [] +is_obsolete: true +consider: GO:0015171 +consider: GO:0015220 + +[Term] +id: GO:0015360 +name: acetate:proton symporter activity +namespace: molecular_function +alt_id: GO:0015357 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in)." [TC:2.A.44.4.1] +synonym: "acetate:hydrogen symporter activity" EXACT [] +synonym: "hydrogen:acetate symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0043893 ! acetate:cation symporter activity + +[Term] +id: GO:0015361 +name: low-affinity sodium:dicarboxylate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.47.1.1] +synonym: "low affinity sodium:dicarboxylate cotransporter activity" BROAD [] +synonym: "low affinity sodium:dicarboxylate symporter activity" EXACT [] +xref: Reactome:R-HSA-433131 "NaDC1 co-transports dicarboxylic acids and a sodium ion" +is_a: GO:0017153 ! sodium:dicarboxylate symporter activity + +[Term] +id: GO:0015362 +name: high-affinity sodium:dicarboxylate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.47.1.4] +synonym: "high affinity sodium:dicarboxylate cotransporter activity" BROAD [] +synonym: "high affinity sodium:dicarboxylate symporter activity" EXACT [] +xref: Reactome:R-HSA-433101 "NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion" +is_a: GO:0017153 ! sodium:dicarboxylate symporter activity + +[Term] +id: GO:0015363 +name: obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" EXACT [] +is_obsolete: true +consider: GO:0005310 +consider: GO:0015138 +consider: GO:0015140 +consider: GO:0015141 +consider: GO:0015297 + +[Term] +id: GO:0015364 +name: dicarboxylate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out)." [TC:2.A.29.2.3] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0015366 +name: malate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in)." [TC:2.A.16.2.1] +synonym: "L-malic acid permease" RELATED [GOC:vw] +synonym: "L-malic acid:proton symporter activity" RELATED [GOC:vw] +synonym: "malate permease" RELATED [GOC:vw] +synonym: "malate:hydrogen symporter activity" EXACT [] +is_a: GO:0015140 ! malate transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0015367 +name: oxoglutarate:malate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out)." [TC:2.A.29.2.1] +synonym: "2-oxoglutarate/malate carrier protein" EXACT [Wikipedia:Mitochondrial_carrier] +xref: Reactome:R-HSA-198440 "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]" +xref: Reactome:R-HSA-376851 "Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane" +is_a: GO:0015139 ! alpha-ketoglutarate transmembrane transporter activity +is_a: GO:0015140 ! malate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0015368 +name: calcium:cation antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in)." [TC:2.A.19.-.-] +xref: Reactome:R-HSA-425822 "K+-independent Li+/Ca2+ exchanger transport" +is_a: GO:0015085 ! calcium ion transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:0072509 ! divalent inorganic cation transmembrane transporter activity + +[Term] +id: GO:0015369 +name: calcium:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in)." [TC:2.A.19.2.-] +synonym: "calcium:hydrogen antiporter activity" EXACT [] +xref: Reactome:R-HSA-8949687 "LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix)" +xref: RHEA:29671 +is_a: GO:0005451 ! monovalent cation:proton antiporter activity +is_a: GO:0015368 ! calcium:cation antiporter activity +is_a: GO:0051139 ! metal ion:proton antiporter activity + +[Term] +id: GO:0015370 +name: solute:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in)." [GOC:ai] +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] +xref: Reactome:R-HSA-8876283 "SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol" +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0015371 +name: galactose:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in)." [TC:2.A.21.3.-] +is_a: GO:0005354 ! galactose transmembrane transporter activity +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0015372 +name: obsolete glutamate/aspartate:sodium symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in)." [TC:2.A.23.1.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "glutamate/aspartate:sodium symporter activity" EXACT [] +is_obsolete: true +consider: GO:0005283 +consider: GO:0005313 +consider: GO:0015183 + +[Term] +id: GO:0015373 +name: anion:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in)." [TC:2.A.21.5.-] +synonym: "monovalent anion:sodium symporter activity" EXACT [] +is_a: GO:0015296 ! anion:cation symporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0015374 +name: neutral, basic amino acid:sodium:chloride symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in)." [TC:2.A.22.2.3] +synonym: "neutral, cationic amino acid:sodium:chloride symporter activity" RELATED [] +is_a: GO:0005283 ! amino acid:sodium symporter activity +relationship: part_of GO:0006821 ! chloride transport + +[Term] +id: GO:0015375 +name: glycine:sodium symporter activity +namespace: molecular_function +alt_id: GO:0015656 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in)." [GOC:ai] +xref: Reactome:R-HSA-444120 "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5660840 "Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol" +is_a: GO:0005295 ! neutral amino acid:sodium symporter activity +is_a: GO:0005328 ! neurotransmitter:sodium symporter activity +is_a: GO:0015187 ! glycine transmembrane transporter activity + +[Term] +id: GO:0015376 +name: obsolete betaine/GABA:sodium symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in)." [TC:2.A.22.3.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "betaine/GABA:sodium symporter activity" EXACT [] +is_obsolete: true +consider: GO:0005332 +consider: GO:0015185 +consider: GO:0015199 +consider: GO:0015370 + +[Term] +id: GO:0015377 +name: cation:chloride symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in)." [TC:2.A.30.-.-] +synonym: "cation:chloride cotransporter activity" BROAD [] +is_a: GO:0015108 ! chloride transmembrane transporter activity +is_a: GO:0015296 ! anion:cation symporter activity + +[Term] +id: GO:0015378 +name: sodium:chloride symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in)." [TC:2.A.30.4.-] +xref: Reactome:R-HSA-426130 "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol" +xref: Reactome:R-HSA-5623705 "Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol" +is_a: GO:0015373 ! anion:sodium symporter activity +is_a: GO:0015377 ! cation:chloride symporter activity + +[Term] +id: GO:0015379 +name: potassium:chloride symporter activity +namespace: molecular_function +alt_id: GO:0022820 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in)." [TC:2.A.30.5.-] +synonym: "potassium ion symporter activity" BROAD [] +xref: Reactome:R-HSA-426155 "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region" +xref: Reactome:R-HSA-5623806 "Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region" +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015377 ! cation:chloride symporter activity + +[Term] +id: GO:0015381 +name: high-affinity sulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity sulfate permease activity" RELATED [] +synonym: "high affinity sulfate transmembrane transporter activity" EXACT [] +synonym: "high affinity sulphate permease activity" EXACT [] +is_a: GO:0008271 ! secondary active sulfate transmembrane transporter activity + +[Term] +id: GO:0015382 +name: sodium:sulfate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in)." [TC:2.A.47.1.2] +synonym: "sodium:sulfate cotransporter activity" BROAD [] +synonym: "sodium:sulphate symporter activity" EXACT [] +xref: Reactome:R-HSA-433099 "NaS2 co-transports sulphate and two sodium ions" +xref: Reactome:R-HSA-433114 "NaS1 co-transports sulphate and a sodium ion" +is_a: GO:0008271 ! secondary active sulfate transmembrane transporter activity +is_a: GO:0015373 ! anion:sodium symporter activity + +[Term] +id: GO:0015383 +name: sulfate:bicarbonate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out)." [TC:2.A.53.2.2] +synonym: "sulphate:bicarbonate antiporter activity" EXACT [] +is_a: GO:0008271 ! secondary active sulfate transmembrane transporter activity +is_a: GO:0015106 ! bicarbonate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0015385 +name: sodium:proton antiporter activity +namespace: molecular_function +alt_id: GO:0015502 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [TC:2.A.35.1.1, TC:2.A.36.-.-] +synonym: "pH-dependent sodium:hydrogen antiporter activity" NARROW [] +synonym: "pH-dependent sodium:proton antiporter activity" NARROW [] +synonym: "sodium/hydrogen antiporter activity" EXACT [] +synonym: "sodium:hydrogen antiporter activity" EXACT [] +synonym: "sodium:hydrogen exchange activity" EXACT [] +synonym: "sodium:hydrogen exchanger" EXACT [] +xref: Reactome:R-HSA-2872444 "SLC9B1/C2 exchange Na+ for H+" +xref: Reactome:R-HSA-2872463 "SLC9C1 exchanges Na+ for H+" +xref: Reactome:R-HSA-425965 "SLC9A9 exchanges Na+ for H+ across the late endosome membrane" +xref: Reactome:R-HSA-425983 "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane" +xref: Reactome:R-HSA-425994 "Na+/H+ exchanger transport (at cell membrane)" +xref: Reactome:R-HSA-426015 "Na+/H+ exchanger transport (at trans-golgi membrane)" +xref: Reactome:R-HSA-5661039 "Defective SLC9A6 does not exchange Na+ for H+ across the early endosome membrane" +xref: Reactome:R-HSA-5661086 "Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane" +xref: RHEA:29251 +is_a: GO:0005451 ! monovalent cation:proton antiporter activity +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0051139 ! metal ion:proton antiporter activity + +[Term] +id: GO:0015386 +name: potassium:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in)." [TC:2.A.37.-.-] +synonym: "potassium:hydrogen antiporter activity" EXACT [] +xref: RHEA:29467 +is_a: GO:0005451 ! monovalent cation:proton antiporter activity +is_a: GO:0022821 ! potassium ion antiporter activity + +[Term] +id: GO:0015387 +name: potassium:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in)." [TC:2.A.38.-.-] +synonym: "potassium:hydrogen symporter activity" EXACT [] +xref: RHEA:28490 +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0015389 +name: pyrimidine- and adenine-specific:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in)." [TC:2.A.41.2.3] +is_a: GO:0005345 ! purine nucleobase transmembrane transporter activity +is_a: GO:0005350 ! pyrimidine nucleobase transmembrane transporter activity +is_a: GO:0005415 ! nucleoside:sodium symporter activity +is_a: GO:0015391 ! nucleobase:cation symporter activity + +[Term] +id: GO:0015390 +name: purine-specific nucleoside:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in)." [TC:2.A.41.2.1] +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0015391 +name: nucleobase:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in)." [GOC:ai] +is_a: GO:0015205 ! nucleobase transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity + +[Term] +id: GO:0015393 +name: obsolete uracil/uridine permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "uracil/uridine permease activity" EXACT [] +is_obsolete: true +consider: GO:0015210 +consider: GO:0015213 +consider: GO:0022857 + +[Term] +id: GO:0015394 +name: uridine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in)." [GOC:mtg_transport] +synonym: "nucleoside (uridine) permease activity" RELATED [] +synonym: "uridine:hydrogen ion symporter activity" EXACT [] +is_a: GO:0015213 ! uridine transmembrane transporter activity +is_a: GO:0015506 ! nucleoside:proton symporter activity + +[Term] +id: GO:0015395 +name: nucleoside transmembrane transporter activity, down a concentration gradient +namespace: molecular_function +alt_id: GO:0015396 +alt_id: GO:0015397 +def: "Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient." [PMID:10353709, PMID:11749958, PMID:12446811] +synonym: "equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity" NARROW [] +synonym: "equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity" NARROW [] +synonym: "equilibrative nucleoside transporter activity" EXACT [] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity + +[Term] +id: GO:0015398 +name: high-affinity secondary active ammonium transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] +synonym: "high affinity secondary active ammonium transmembrane transporter activity" EXACT [] +is_a: GO:0008519 ! ammonium transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015399 +name: primary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources." [GOC:mtg_transport, ISBN:0815340729, TC:3.-.-.-.-] +synonym: "primary active transporter" RELATED [] +xref: TC:3 +is_a: GO:0022804 ! active transmembrane transporter activity + +[Term] +id: GO:0015400 +name: low-affinity secondary active ammonium transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mtg_transport, ISBN:0815340729] +synonym: "low affinity ammonium transmembrane transporter activity" RELATED [] +synonym: "low affinity secondary active ammonium transmembrane transporter activity" EXACT [] +is_a: GO:0008519 ! ammonium transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015401 +name: urea:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in)." [TC:2.A.21.6.1] +synonym: "urea active transmembrane transporter activity" EXACT [] +is_a: GO:0015204 ! urea transmembrane transporter activity +is_a: GO:0015370 ! solute:sodium symporter activity + +[Term] +id: GO:0015406 +name: obsolete ABC-type uptake permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. +synonym: "ABC-type uptake permease activity" EXACT [] +is_obsolete: true +consider: GO:0042626 +consider: GO:0043190 + +[Term] +id: GO:0015407 +name: ATPase-coupled monosaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported." [EC:3.6.3.17] +synonym: "ATP phosphohydrolase (monosaccharide-importing)" EXACT [EC:3.6.3.17] +synonym: "ATP-dependent monosaccharide transmembrane transporter activity" EXACT [] +synonym: "monosaccharide ABC transporter" NARROW [] +synonym: "monosaccharide-importing ATPase activity" NARROW [] +synonym: "monosaccharide-transporting ATPase activity" EXACT [] +xref: EC:3.6.3.17 +xref: MetaCyc:3.6.3.17-RXN +xref: RHEA:29900 +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0015408 +name: ATPase-coupled ferric iron transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in)." [EC:7.2.2.7] +synonym: "ABC-type Fe3+ transporter" EXACT [] +synonym: "Fe3+-transporting ATPase activity" EXACT [EC:7.2.2.7] +synonym: "ferric ABC transporter" NARROW [] +synonym: "ferric transporting ATPase activity" EXACT [] +synonym: "ferric-transporting ATPase activity" EXACT [] +xref: EC:7.2.2.7 +xref: MetaCyc:3.6.3.30-RXN +xref: RHEA:12332 +is_a: GO:0015091 ! ferric iron transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015410 +name: manganese transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in)." [EC:7.2.2.5] +synonym: "ABC-type Mn(2+) transporter" EXACT [EC:7.2.2.5] +synonym: "ATP-dependent manganese transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled manganese transmembrane transporter activity" RELATED [] +synonym: "manganese ABC transporter" NARROW [] +synonym: "manganese-transporting ATPase activity" EXACT [EC:7.2.2.5] +xref: EC:7.2.2.5 +xref: MetaCyc:3.6.3.35-RXN +xref: Reactome:R-HSA-5692462 "ATP13A1 transports Mn2+ from cytosol to ER lumen" +xref: RHEA:17365 +is_a: GO:0005384 ! manganese ion transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015411 +name: ATPase-coupled taurine transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in)." [EC:7.6.2.7] +synonym: "ATP phosphohydrolase (taurine-importing)" EXACT [EC:7.6.2.7] +synonym: "ATP-dependent taurine transporter activity" EXACT [] +synonym: "taurine (2-aminoethane sulfonate) porter activity" EXACT [] +synonym: "taurine ABC transporter" NARROW [] +synonym: "taurine-transporting ATPase activity" EXACT [] +xref: EC:7.6.2.7 +xref: MetaCyc:3.6.3.36-RXN +xref: RHEA:14614 +is_a: GO:0005368 ! taurine transmembrane transporter activity +is_a: GO:0033283 ! ATPase-coupled organic acid transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015412 +name: ATPase-coupled molybdate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in)." [EC:7.3.2.5] +synonym: "ATP phosphohydrolase (molybdate-importing)" EXACT [EC:7.3.2.5] +synonym: "molybdate ABC transporter" NARROW [] +synonym: "molybdate porter activity" EXACT [] +synonym: "molybdate transmembrane-transporting ATPase activity" RELATED [] +synonym: "molybdate transporting ATPase activity" EXACT [] +synonym: "molybdate-transporting ATPase activity" EXACT [EC:7.3.2.5] +xref: EC:7.3.2.5 +xref: MetaCyc:3.6.3.29-RXN +xref: RHEA:22020 +is_a: GO:0015098 ! molybdate ion transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0015413 +name: ATPase-coupled nickel transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0102016 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in)." [EC:7.2.2.11] +synonym: "ATP phosphohydrolase (nickel-importing)" EXACT [EC:7.2.2.11] +synonym: "ATP-dependent nickel transmembrane transporter activity" EXACT [] +synonym: "nickel ABC transporter" NARROW [] +synonym: "nickel ABC transporter activity" EXACT [] +synonym: "nickel porter activity" EXACT [] +synonym: "nickel transporting ATPase activity" EXACT [] +synonym: "nickel-transporting ATPase activity" EXACT [] +xref: EC:7.2.2.11 +xref: MetaCyc:3.6.3.24-RXN +xref: MetaCyc:ABC-20-RXN +xref: RHEA:15557 +is_a: GO:0015099 ! nickel cation transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015414 +name: ATPase-coupled nitrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in)." [EC:7.3.2.4] +synonym: "ATP phosphohydrolase (nitrate-importing)" EXACT [EC:7.3.2.4] +synonym: "nitrate ABC transporter" NARROW [] +synonym: "nitrate transmembrane-transporting ATPase activity" RELATED [] +synonym: "nitrate transporting ATPase activity" EXACT [] +synonym: "nitrate-transporting ATPase activity" EXACT [EC:7.3.2.4] +xref: EC:7.3.2.4 +xref: MetaCyc:3.6.3.26-RXN +xref: RHEA:13181 +is_a: GO:0015112 ! nitrate transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0015415 +name: ATPase-coupled phosphate ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in)." [EC:7.3.2.1] +synonym: "ABC phosphate transporter activity" NARROW [EC:7.3.2.1] +synonym: "ATP phosphohydrolase (phosphate-importing)" EXACT [EC:7.3.2.1] +synonym: "phosphate ABC transporter" NARROW [] +synonym: "phosphate ion transmembrane-transporting ATPase activity" RELATED [] +synonym: "phosphate porter activity" EXACT [] +synonym: "phosphate transporting ATPase activity" EXACT [] +synonym: "phosphate-transporting ATPase activity" EXACT [EC:7.3.2.1] +xref: EC:7.3.2.1 +xref: RHEA:24440 +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0015416 +name: ATPase-coupled organic phosphonate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0102017 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)." [EC:7.3.2.2] +synonym: "alkylphosphonate ABC transporter activity" NARROW [] +synonym: "alkylphosphonate transmembrane-transporting ATPase activity" NARROW [] +synonym: "ATP phosphohydrolase (phosphonate-transporting)" EXACT [] +synonym: "ATPase-coupled alkylphosphonate transmembrane transporter activity" NARROW [] +synonym: "organic phosphonate transmembrane-transporting ATPase activity" RELATED [] +synonym: "phosphonate ABC transporter" NARROW [] +synonym: "phosphonate transporting ATPase activity" EXACT [] +synonym: "phosphonate-transporting ATPase activity" EXACT [] +xref: EC:7.3.2.2 +xref: MetaCyc:3.6.3.28-RXN +xref: MetaCyc:ABC-23-RXN +xref: RHEA:18065 +is_a: GO:0015604 ! organic phosphonate transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0015417 +name: ATPase-coupled polyamine transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in)." [EC:7.6.2.11] +synonym: "ABC-type polyamine transporter" EXACT [EC:7.6.2.11] +synonym: "ATP-dependent polyamine transmembrane transporter activity" EXACT [] +synonym: "polyamine ABC transporter" NARROW [EC:7.6.2.11] +synonym: "polyamine porter activity" EXACT [] +synonym: "polyamine-importing ATPase activity" NARROW [] +synonym: "polyamine-transporting ATPase activity" EXACT [EC:7.6.2.11] +xref: EC:7.6.2.11 +xref: MetaCyc:3.6.3.31-RXN +is_a: GO:0015203 ! polyamine transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0015418 +name: ATPase-coupled quaternary ammonium compound transmembrane transporting activity +namespace: molecular_function +alt_id: GO:0102908 +def: "Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in)." [EC:7.6.2.9, GOC:pz] +synonym: "ATP-dependent quaternary-ammonium compound transmembrane transporting activity" EXACT [] +synonym: "glycine betaine/proline porter activity" NARROW [] +synonym: "quarternary amine transporter activity" BROAD [] +synonym: "quaternary amine uptake transporter activity" EXACT [] +synonym: "quaternary-amine-transporting ATPase activity" EXACT [] +synonym: "quaternary-ammonium-compound ABC transporter" RELATED [] +synonym: "quaternary-ammonium-compound-transporting ATPase activity" EXACT [] +xref: EC:7.6.2.9 +xref: MetaCyc:3.6.3.32-RXN +xref: MetaCyc:RXN-8638 +xref: RHEA:11036 +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015419 +name: ATPase-coupled sulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in)." [EC:7.3.2.3] +synonym: "ATP phosphohydrolase (sulfate-importing) activity" EXACT [EC:7.3.2.3] +synonym: "sulfate ABC transporter" NARROW [] +synonym: "sulfate transmembrane-transporting ATPase activity" RELATED [] +synonym: "sulfate transporting ATPase activity" EXACT [] +synonym: "sulfate-transporting ATPase activity" EXACT [EC:7.3.2.3] +synonym: "sulfate/thiosulfate porter activity" EXACT [] +synonym: "sulphate transporting ATPase activity" EXACT [] +synonym: "sulphate-transporting ATPase activity" EXACT [] +xref: EC:3.6.3.25 +xref: MetaCyc:3.6.3.25-RXN +xref: RHEA:10192 +is_a: GO:0015116 ! sulfate transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0015420 +name: ATPase-coupled vitamin B12 transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015235 +alt_id: GO:0102023 +def: "Catalysis of the reaction: ATP(4-) + cob(I)alamin + H2O <=> ADP(3-) + hydrogenphosphate + cob(I)alamin + H+. Cobalamin is also known as vitamin B12." [EC:7.6.2.8, GOC:pz] +synonym: "ATP-dependent cobalamin transmembrane transporter activity" EXACT [] +synonym: "ATP-dependent vitamin B12 transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled cobalamin transmembrane transporter activity" EXACT [] +synonym: "cobalamin ABC transporter" NARROW [] +synonym: "cobalamin porter activity" BROAD [] +synonym: "cobalamin transporter activity" BROAD [] +synonym: "cobalamin-transporting ATPase activity" EXACT [] +synonym: "vitamin B12 ABC transporter activity" EXACT [] +synonym: "vitamin B12 porter activity" BROAD [] +synonym: "vitamin B12 transporter activity" BROAD [] +synonym: "vitamin B12-transporting ATPase activity" BROAD [] +xref: EC:7.6.2.8 +xref: MetaCyc:3.6.3.33-RXN +xref: MetaCyc:ABC-5-RXN +xref: Reactome:R-HSA-3000122 "CD320 transports extracellular TCII:Cbl to endosome" +xref: Reactome:R-HSA-3000238 "LMBRD1 transports lysosomal Cbl to cytosol" +xref: Reactome:R-HSA-3095901 "ABCC1 transports cytosolic Cbl to extracellular region" +xref: Reactome:R-HSA-3315437 "Defective LMBRD1 does not transport lysosomal Cbl to cytosol" +xref: RHEA:17873 +xref: RHEA:32831 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0015889 ! cobalamin transport + +[Term] +id: GO:0015421 +name: ATPase-coupled oligopeptide transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in)." [EC:7.4.2.6] +synonym: "ABC-type oligopeptide transporter" EXACT [EC:7.4.2.6] +synonym: "ATP-dependent oligopeptide transmembrane transporter activity" EXACT [] +synonym: "oligopeptide ABC transporter" NARROW [] +synonym: "oligopeptide permease activity" RELATED [EC:7.4.2.6] +synonym: "oligopeptide-transporting ATPase activity" EXACT [EC:7.4.2.6] +xref: EC:7.4.2.6 +xref: MetaCyc:3.6.3.23-RXN +xref: Reactome:R-HSA-5223317 "ABCB9 transports peptides from cytosol to lysosomal lumen" +is_a: GO:0015440 ! ATPase-coupled peptide transmembrane transporter activity +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity + +[Term] +id: GO:0015422 +name: ATPase-coupled oligosaccharide transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015609 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in)." [EC:7.5.2.2] +synonym: "ABC-type oligosaccharide transporter" EXACT [EC:7.5.2.2] +synonym: "ATP-dependent oligosaccharide transmembrane transporter activity" EXACT [] +synonym: "maltooligosaccharide porter activity" NARROW [] +synonym: "maltooligosaccharide-importing ATPase activity" NARROW [] +synonym: "oligosaccharide ABC transporter" NARROW [] +synonym: "oligosaccharide-transporting ATPase activity" EXACT [EC:7.5.2.2] +xref: EC:7.5.2.2 +xref: MetaCyc:3.6.3.18-RXN +is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0015423 +name: ATPase-coupled maltose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in)." [EC:7.5.2.1] +synonym: "ABC-type maltose transporter" EXACT [EC:7.5.2.1] +synonym: "ATP-dependent maltose transmembrane transporter activity" EXACT [] +synonym: "maltose ABC transporter" NARROW [] +synonym: "maltose-transporting ATPase activity" EXACT [EC:7.5.2.1] +xref: EC:7.5.2.1 +xref: MetaCyc:3.6.3.19-RXN +xref: RHEA:22132 +is_a: GO:0005363 ! maltose transmembrane transporter activity +is_a: GO:0015422 ! ATPase-coupled oligosaccharide transmembrane transporter activity +relationship: part_of GO:1904981 ! maltose transmembrane transport + +[Term] +id: GO:0015424 +name: ATPase-coupled amino acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0032518 +alt_id: GO:0032520 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out)." [GOC:ai, GOC:mah] +synonym: "amino acid ABC transporter" NARROW [] +synonym: "amino acid-exporting ATPase activity" RELATED [] +synonym: "amino acid-importing ATPase activity" RELATED [] +synonym: "amino acid-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent amino acid transmembrane transporter activity" EXACT [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +is_a: GO:0033284 ! ATPase-coupled carboxylic acid transmembrane transporter activity + +[Term] +id: GO:0015425 +name: ATPase-coupled nonpolar-amino acid transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in)." [EC:7.4.2.2] +synonym: "ATP-dependent nonpolar-amino acid transporter activity" EXACT [] +synonym: "leucine/isoleucine/valine porter activity" RELATED [] +synonym: "nonpolar amino acid-transporting ATPase activity" EXACT [] +synonym: "nonpolar-amino acid ABC transporter" EXACT [] +synonym: "nonpolar-amino acid-transporting ATPase activity" EXACT [] +synonym: "nonpolar-amino-acid-transporting ATPase activity" EXACT [] +xref: EC:7.4.2.2 +xref: MetaCyc:3.6.3.22-RXN +xref: TC:3.A.1.4.1 +is_a: GO:0015424 ! ATPase-coupled amino acid transmembrane transporter activity + +[Term] +id: GO:0015426 +name: ATPase-coupled polar amino acid-transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)." [EC:7.4.2.1] +synonym: "ATP-dependent polar amino acid-transporter activity" EXACT [] +synonym: "cystine/diaminopimelate porter activity" RELATED [] +synonym: "glutamate/aspartate porter activity" RELATED [] +synonym: "histidine permease activity" NARROW [EC:7.4.2.1] +synonym: "histidine/arginine/lysine/ornithine porter activity" RELATED [] +synonym: "polar amino acid uptake transporter activity" EXACT [] +synonym: "polar amino acid-importing ATPase activity" EXACT [] +synonym: "polar-amino acid ABC transporter" NARROW [] +synonym: "polar-amino acid-importing ATPase activity" EXACT [] +synonym: "polar-amino acid-transporting ATPase activity" EXACT [] +synonym: "polar-amino-acid-transporting ATPase activity" EXACT [EC:7.4.2.1] +xref: EC:7.4.2.1 +xref: MetaCyc:3.6.3.21-RXN +is_a: GO:0015424 ! ATPase-coupled amino acid transmembrane transporter activity + +[Term] +id: GO:0015427 +name: obsolete ABC-type efflux porter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. +synonym: "ABC-type efflux porter activity" EXACT [] +is_obsolete: true +consider: GO:0042626 +consider: GO:0043190 + +[Term] +id: GO:0015428 +name: obsolete type I protein secretor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because it does not accurately reflect the function of the proteins involved. +synonym: "type I protein secretor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015429 +name: obsolete peroxisomal fatty acyl transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a gene product and it contains both component and function information. +synonym: "peroxisomal fatty acyl transporter" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015430 +name: ATPase-coupled glycerol-3-phosphate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015610 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in)." [EC:7.6.2.10] +synonym: "ABC-type glycerol 3-phosphate transporter" EXACT [EC:7.6.2.10] +synonym: "glycerol phosphate-importing ATPase activity" NARROW [] +synonym: "glycerol-3-phosphate ABC transporter" NARROW [EC:7.6.2.10] +synonym: "glycerol-3-phosphate-transporting ATPase" EXACT [EC:7.6.2.10] +synonym: "glycerol-phosphate porter activity" NARROW [] +xref: EC:7.6.2.10 +xref: MetaCyc:3.6.3.20-RXN +xref: RHEA:21669 +is_a: GO:0015169 ! glycerol-3-phosphate transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015431 +name: ATPase-coupled glutathione S-conjugate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0071997 +def: "Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out)." [GOC:jl, PMID:1455517] +synonym: "ATP-dependent glutathione S-conjugate export pump" EXACT [] +synonym: "conjugate transporter activity" BROAD [] +synonym: "glutathione S-conjugate-exporting ATPase activity" NARROW [] +synonym: "glutathione S-conjugate-transporting ATPase activity" RELATED [EC:7.6.2.3] +synonym: "GS-X pump" EXACT [] +synonym: "MRP1/GS-X pump" EXACT [] +xref: EC:7.6.2.3 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +created_by: mah +creation_date: 2010-10-25T02:32:02Z + +[Term] +id: GO:0015432 +name: ATPase-coupled bile acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate." [TC:3.A.1.207.2] +synonym: "ATP-dependent bile acid transmembrane transporter activity" EXACT [] +synonym: "bile acid porter activity" NARROW [] +synonym: "bile acid-exporting ATPase activity" BROAD [] +xref: Reactome:R-HSA-193362 "ABCB11 transports bile salts from cytosol to extracellular region" +xref: Reactome:R-HSA-194153 "Transport (efflux) of bile salts by ABCC3 (MRP3)" +xref: Reactome:R-HSA-5678517 "Defective ABCB11 does not transport bile salts from cytosol to extracellular region" +is_a: GO:0015125 ! bile acid transmembrane transporter activity +is_a: GO:0033285 ! ATPase-coupled monocarboxylic acid transmembrane transporter activity +is_a: GO:0034040 ! ATPase-coupled lipid transmembrane transporter activity + +[Term] +id: GO:0015433 +name: ATPase-coupled peptide antigen transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate." [TC:3.A.1.209.1] +synonym: "ATP-dependent peptide antigen transmembrane transporter activity" EXACT [] +synonym: "major histocompatibility peptide transporter activity" EXACT [] +synonym: "peptide antigen ABC transporter" NARROW [] +synonym: "peptide antigen transporter activity" BROAD [] +synonym: "peptide antigen-transporting ATPase activity" EXACT [] +xref: Reactome:R-HSA-1236949 "Translocation of antigenic peptides back to phagosomes via TAP" +xref: Reactome:R-HSA-983144 "Transport of Antigen peptide in to ER" +is_a: GO:0015440 ! ATPase-coupled peptide transmembrane transporter activity + +[Term] +id: GO:0015434 +name: ATPase-coupled cadmium transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole)." [EC:7.2.2.2] +synonym: "ATP-dependent cadmium transmembrane transporter activity" EXACT [] +synonym: "cadmium ABC transporter" NARROW [] +synonym: "cadmium-transporting ATPase activity" EXACT [EC:7.2.2.2] +xref: EC:7.2.2.2 +xref: MetaCyc:3.6.3.46-RXN +is_a: GO:0015086 ! cadmium ion transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015435 +name: obsolete ABC-type efflux permease activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. +synonym: "ABC-type efflux permease activity" EXACT [] +is_obsolete: true +consider: GO:0042626 +consider: GO:0043190 + +[Term] +id: GO:0015436 +name: ATPase-coupled capsular-polysaccharide transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out)." [EC:7.6.2.12] +synonym: "ATP phosphohydrolase (capsular-polysaccharide-exporting)" EXACT [EC:7.6.2.12] +synonym: "ATP-dependent capsular-polysaccharide transporter activity" EXACT [] +synonym: "capsular-polysaccharide ABC transporter" NARROW [] +synonym: "capsular-polysaccharide-transporting ATPase activity" EXACT [] +xref: EC:7.6.2.12 +xref: MetaCyc:3.6.3.38-RXN +is_a: GO:0015161 ! capsular polysaccharide transmembrane transporter activity +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0015437 +name: lipopolysaccharide floppase activity +namespace: molecular_function +def: "Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [EC:7.5.2.5] +synonym: "ATP-dependent intramembrane lipopolysaccharide transporter activity" EXACT [] +synonym: "ATPase-coupled intramembrane lipopolysaccharide transporter activity" BROAD [] +synonym: "lipopolysaccharide ABC transporter" NARROW [] +synonym: "lipopolysaccharide floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "lipopolysaccharide-transporting ATPase activity" EXACT [] +synonym: "LPS-transporting ATPase activity" EXACT [] +xref: EC:7.5.2.5 +is_a: GO:0140328 ! floppase activity +relationship: part_of GO:0015920 ! lipopolysaccharide transport + +[Term] +id: GO:0015438 +name: ATPase-coupled teichoic acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015162 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out)." [EC:7.5.2.4, PMID:7565096] +synonym: "ABC-type teichoic-acid transporter" EXACT [EC:7.5.2.4] +synonym: "ATP-dependent teichoic acid transmembrane transporter activity" EXACT [] +synonym: "teichoic acid transmembrane transporter activity" BROAD [] +synonym: "teichoic-acid ABC transporter" NARROW [] +synonym: "teichoic-acid-transporting ATPase activity" EXACT [EC:7.5.2.4] +xref: EC:7.5.2.4 +xref: MetaCyc:3.6.3.40-RXN +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015777 ! teichoic acid transport + +[Term] +id: GO:0015439 +name: ATPase-coupled heme transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0103115 +def: "Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out)." [EC:7.6.2.5] +synonym: "ATP-dependent heme transmembrane transporter activity" EXACT [] +synonym: "haem-transporting ATPase activity" EXACT [] +synonym: "heme ABC transporter" NARROW [] +synonym: "heme-transporting ATPase activity" EXACT [] +synonym: "protoheme IX ABC transporter activity" RELATED [] +xref: EC:7.6.2.5 +xref: MetaCyc:3.6.3.41-RXN +xref: MetaCyc:TRANS-RXN0-162 +xref: RHEA:19261 +is_a: GO:0015232 ! heme transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +relationship: part_of GO:0035351 ! heme transmembrane transport + +[Term] +id: GO:0015440 +name: ATPase-coupled peptide transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria." [EC:7.4.2.5] +synonym: "ATP phosphohydrolase (peptide-exporting)" EXACT [EC:7.4.2.5] +synonym: "ATP-dependent peptide transmembrane transporter activity" EXACT [] +synonym: "peptide ABC transporter" NARROW [] +synonym: "peptide-transporting ATPase activity" EXACT [] +xref: EC:7.4.2.5 +xref: MetaCyc:3.6.3.43-RXN +is_a: GO:0033220 ! ATPase-coupled amide-transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0015833 ! peptide transport + +[Term] +id: GO:0015441 +name: ATPase-coupled beta-glucan transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out)." [EC:7.5.2.3] +synonym: "ABC-type beta-glucan transporter" EXACT [EC:7.5.2.3] +synonym: "ATP-dependent beta-glucan transporter activity" EXACT [] +synonym: "beta-glucan ABC transporter" NARROW [] +synonym: "beta-glucan-transporting ATPase activity" EXACT [EC:7.5.2.3] +xref: EC:7.5.2.3 +xref: MetaCyc:3.6.3.42-RXN +xref: RHEA:18453 +is_a: GO:0015160 ! beta-glucan transmembrane transporter activity +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0015442 +name: obsolete hydrogen-/sodium-translocating ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out)." [TC:3.A.2.-.-] +comment: This term was made obsolete because it is a redundant grouping term based on a TC-DB classification. +synonym: "hydrogen-/sodium-translocating ATPase activity" EXACT [] +synonym: "proton-/sodium-translocating ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0008553 +consider: GO:0008554 + +[Term] +id: GO:0015443 +name: obsolete sodium-transporting two-sector ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out)." [EC:3.6.3.15] +comment: This term was made obsolete because it refers to a bifunctional gene product. +synonym: "sodium-transporting two-sector ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0046932 +consider: GO:0046962 + +[Term] +id: GO:0015444 +name: magnesium transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in)." [EC:7.2.2.14] +synonym: "ATP phosphohydrolase (Mg2+-importing)" EXACT [EC:7.2.2.14] +synonym: "magnesium importing ATPase activity" EXACT [] +synonym: "magnesium-translocating P-type ATPase activity" RELATED [EC:7.2.2.14] +synonym: "Mg(2+)-importing ATPase activity" EXACT [EC:7.2.2.14] +synonym: "Mg2+-importing ATPase activity" EXACT [EC:7.2.2.14] +xref: EC:7.2.2.14 +xref: MetaCyc:3.6.3.2-RXN +xref: RHEA:10260 +is_a: GO:0015095 ! magnesium ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015445 +name: silver transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out)." [EC:7.2.2.15] +synonym: "Ag+-exporting ATPase activity" EXACT [EC:7.2.2.15] +synonym: "ATP phosphohydrolase (Ag+-exporting)" EXACT [EC:7.2.2.15] +synonym: "silver exporting ATPase activity" EXACT [] +synonym: "silver-exporting ATPase activity" RELATED [] +xref: EC:7.2.2.15 +xref: MetaCyc:3.6.3.53-RXN +xref: RHEA:14733 +is_a: GO:0015080 ! silver ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0015446 +name: ATPase-coupled arsenite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out)." [EC:3.6.3.16] +synonym: "arsenical pump-driving ATPase activity" EXACT [EC:3.6.3.16] +synonym: "arsenical resistance ATPase activity" EXACT [EC:3.6.3.16] +synonym: "arsenical resistance efflux pump" EXACT [] +synonym: "arsenite ABC transporter" NARROW [] +synonym: "arsenite transporting ATPase activity" EXACT [] +synonym: "arsenite-translocating ATPase activity" EXACT [EC:3.6.3.16] +synonym: "arsenite-transmembrane transporting ATPase activity" RELATED [] +synonym: "arsenite-transporting ATPase activity" EXACT [EC:7.3.2.7, GOC:vw] +synonym: "ATP phosphohydrolase (arsenite-exporting) activity" EXACT [EC:7.3.2.7] +xref: EC:7.3.2.7 +xref: MetaCyc:3.6.3.16-RXN +xref: RHEA:11348 +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:1901683 ! arsenate ion transmembrane transporter activity +relationship: part_of GO:0015700 ! arsenite transport + +[Term] +id: GO:0015447 +name: obsolete type II protein secretor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because it does not accurately reflect the function of the proteins involved. +synonym: "type II protein secretor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015448 +name: obsolete type III protein (virulence-related) secretor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because it does not accurately reflect the function of the proteins involved. +synonym: "type III protein (virulence-related) secretor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015449 +name: obsolete type IV protein (DNA-protein) secretor activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport] +comment: This term was made obsolete because it does not accurately reflect the function of the proteins involved. +synonym: "type IV protein (DNA-protein) secretor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015450 +name: P-P-bond-hydrolysis-driven protein transmembrane transporter activity +namespace: molecular_function +def: "Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated." [GOC:mtg_transport, ISBN:0815340729] +synonym: "protein translocase activity" EXACT [] +xref: EC:7.4.2.3 +xref: EC:7.4.2.4 +xref: Reactome:R-HSA-1222523 "SodB gets secreted" +is_a: GO:0008320 ! protein transmembrane transporter activity +is_a: GO:0015399 ! primary active transmembrane transporter activity + +[Term] +id: GO:0015451 +name: decarboxylation-driven active transmembrane transporter activity +namespace: molecular_function +def: "Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.B.-.-.-] +synonym: "decarboxylation-driven transporter" RELATED [] +xref: EC:7.2.4.1 +xref: EC:7.2.4.2 +xref: EC:7.2.4.3 +xref: EC:7.2.4.4 +xref: EC:7.2.4.5 +xref: TC:3.B +is_a: GO:0015399 ! primary active transmembrane transporter activity + +[Term] +id: GO:0015452 +name: methyl transfer-driven active transmembrane transporter activity +namespace: molecular_function +def: "Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.C.-.-.-] +synonym: "Methyltransfer-driven transporters" EXACT [] +xref: TC:3.C +is_a: GO:0015399 ! primary active transmembrane transporter activity + +[Term] +id: GO:0015453 +name: oxidoreduction-driven active transmembrane transporter activity +namespace: molecular_function +def: "Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.D.-.-.-] +synonym: "Oxidoreduction-driven transporters" EXACT [] +xref: TC:3.D +is_a: GO:0015399 ! primary active transmembrane transporter activity + +[Term] +id: GO:0015454 +name: light-driven active transmembrane transporter activity +namespace: molecular_function +def: "Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.E.-.-.-] +synonym: "Light absorption-driven transporters" EXACT [] +synonym: "light-driven pumps" EXACT [] +xref: TC:3.E +is_a: GO:0015399 ! primary active transmembrane transporter activity + +[Term] +id: GO:0015459 +name: potassium channel regulator activity +namespace: molecular_function +def: "Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification)." [GOC:dos, GOC:mah] +synonym: "potassium channel gating activity" EXACT [] +is_a: GO:0099106 ! ion channel regulator activity +relationship: regulates GO:0005267 ! potassium channel activity + +[Term] +id: GO:0015461 +name: obsolete endosomal oligosaccharide transporter +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "endosomal oligosaccharide transporter" EXACT [] +is_obsolete: true +consider: GO:0005768 +consider: GO:0015157 + +[Term] +id: GO:0015462 +name: ATPase-coupled protein transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in)." [GOC:jl] +synonym: "pilin/fimbrilin exporter activity" NARROW [] +synonym: "protein ABC transporter" NARROW [] +synonym: "protein-transmembrane transporting ATPase activity" RELATED [] +synonym: "protein-transporting ATPase activity" EXACT [] +xref: EC:7.4.2.5 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0015464 +name: acetylcholine receptor activity +namespace: molecular_function +def: "Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +comment: For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'. +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0098960 ! postsynaptic neurotransmitter receptor activity +relationship: has_part GO:0042166 ! acetylcholine binding +relationship: part_of GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0015465 +name: obsolete lysin activity +namespace: molecular_function +def: "OBSOLETE. An agent that can lyse cells." [ISBN:0198547684] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "lysin activity" EXACT [] +is_obsolete: true +consider: GO:0019835 + +[Term] +id: GO:0015466 +name: obsolete autolysin activity +namespace: molecular_function +def: "OBSOLETE. An agent that can lyse the cell in which it is synthesized." [GOC:ma] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "autolysin activity" EXACT [] +is_obsolete: true +consider: GO:0019835 + +[Term] +id: GO:0015467 +name: G-protein activated inward rectifier potassium channel activity +namespace: molecular_function +alt_id: GO:0015273 +def: "Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force." [GOC:cb, GOC:mah] +synonym: "G protein activated inward rectifier potassium channel activity" EXACT [] +synonym: "G protein enhanced inward rectifier potassium channel activity" EXACT [] +synonym: "G-protein enhanced inward rectifier potassium channel activity" EXACT [] +synonym: "G-protein-activated inward rectifier potassium channel activity" EXACT [] +synonym: "G-protein-enhanced inward rectifier potassium channel activity" EXACT [] +xref: Reactome:R-HSA-1013020 "Activation of GIRK/Kir3 Channels" +is_a: GO:0005242 ! inward rectifier potassium channel activity + +[Term] +id: GO:0015468 +name: obsolete colicin +namespace: molecular_function +def: "OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it." [TC:1.C.1.-.-] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "colicin" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005198 +consider: GO:0009405 +consider: GO:0019835 +consider: GO:0046930 +consider: GO:0046931 +consider: GO:0090729 + +[Term] +id: GO:0015469 +name: obsolete channel-forming toxin activity +namespace: molecular_function +def: "OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell." [GOC:ai] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "channel-forming toxin activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0015267 +consider: GO:0035915 +consider: GO:0046930 +consider: GO:0090729 + +[Term] +id: GO:0015470 +name: obsolete bacteriocin activity +namespace: molecular_function +def: "OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor." [ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "bacteriocin activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0019835 + +[Term] +id: GO:0015471 +name: nucleoside-specific channel forming porin activity +namespace: molecular_function +def: "Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015472 +name: obsolete fimbrium-specific chaperone activity +namespace: molecular_function +def: "OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function." [GOC:jl, GOC:rb, PMID:7906046] +comment: This term was made obsolete because it refers to a class of proteins and a biological process rather than a molecular function. +synonym: "fimbrium-specific chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0009297 +consider: GO:0030674 +consider: GO:0044183 +consider: GO:0051082 + +[Term] +id: GO:0015473 +name: fimbrial usher porin activity +namespace: molecular_function +def: "A porin that acts in the assembly of fimbria together with fimbrial chaperone." [TC:1.B.11.-.-] +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015474 +name: autotransporter activity +namespace: molecular_function +def: "Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729, TC:1.B.12.-.-] +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015475 +name: adhesin autotransporter activity +namespace: molecular_function +def: "Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015474 ! autotransporter activity + +[Term] +id: GO:0015476 +name: hemaglutinin autotransporter activity +namespace: molecular_function +def: "Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015474 ! autotransporter activity + +[Term] +id: GO:0015477 +name: obsolete receptor porin activity +namespace: molecular_function +def: "OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane." [GOC:mtg_transport, ISBN:0815340729, TC:1.B.13.-.-] +comment: This term was made obsolete because it combines two functions that are not linked. +synonym: "receptor porin activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015478 +name: oligosaccharide transporting porin activity +namespace: molecular_function +def: "Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] +synonym: "raffinose porin" NARROW [] +is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015479 +name: obsolete outer membrane exporter porin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "outer membrane exporter porin" EXACT [] +is_obsolete: true +consider: GO:0009279 +consider: GO:0015288 + +[Term] +id: GO:0015480 +name: obsolete secretin (sensu Bacteria) +namespace: molecular_function +def: "OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm)." [TC:1.B.22.-.-] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "secretin (sensu Bacteria)" EXACT [] +is_obsolete: true +consider: GO:0008320 +consider: GO:0045203 + +[Term] +id: GO:0015481 +name: maltose transporting porin activity +namespace: molecular_function +def: "Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] +synonym: "maltoporin" EXACT [] +xref: Wikipedia:Maltoporin +is_a: GO:0005363 ! maltose transmembrane transporter activity +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015482 +name: obsolete voltage-gated anion channel porin activity +namespace: molecular_function +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because it wrongly combines voltage-gated anion channel activity and porin activity. +synonym: "voltage-dependent anion channel porin activity" EXACT [] +synonym: "voltage-gated anion channel porin activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015483 +name: long-chain fatty acid transporting porin activity +namespace: molecular_function +def: "Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] +is_a: GO:0005324 ! long-chain fatty acid transporter activity +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +is_a: GO:0015288 ! porin activity + +[Term] +id: GO:0015484 +name: obsolete hemolysin activity +namespace: molecular_function +def: "OBSOLETE. Any substance that causes the lysis of red blood cells." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "hemolysin activity" EXACT [] +is_obsolete: true +consider: GO:0019836 + +[Term] +id: GO:0015485 +name: cholesterol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:jl, ISBN:0198506732] +is_a: GO:0032934 ! sterol binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0015486 +name: glycoside-pentoside-hexuronide:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+." [TC:2.A.2.-.-] +is_a: GO:0005402 ! carbohydrate:cation symporter activity + +[Term] +id: GO:0015487 +name: melibiose:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in)." [TC:2.A.2.1.1] +synonym: "melibiose permease activity" RELATED [] +synonym: "melibiose:monovalent cation symporter activity" EXACT [] +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015156 ! melibiose transmembrane transporter activity + +[Term] +id: GO:0015488 +name: glucuronide:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in)." [TC:2.A.2.3.1] +synonym: "glucuronide:monovalent cation symporter activity" EXACT [] +synonym: "glucuronoside permease activity" RELATED [] +is_a: GO:0015164 ! glucuronoside transmembrane transporter activity +is_a: GO:0015486 ! glycoside-pentoside-hexuronide:cation symporter activity + +[Term] +id: GO:0015489 +name: putrescine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine." [GOC:ai] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015203 ! polyamine transmembrane transporter activity +relationship: part_of GO:0015847 ! putrescine transport + +[Term] +id: GO:0015491 +name: cation:cation antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out)." [GOC:ai] +is_a: GO:0015298 ! solute:cation antiporter activity + +[Term] +id: GO:0015492 +name: phenylalanine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in)." [TC:2.A.3.1.1] +synonym: "phenylalanine:hydrogen symporter activity" EXACT [] +is_a: GO:0015494 ! aromatic amino acid:proton symporter activity + +[Term] +id: GO:0015493 +name: lysine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in)." [TC:2.A.3.1.2] +synonym: "lysine:hydrogen symporter activity" EXACT [] +is_a: GO:0005280 ! amino acid:proton symporter activity + +[Term] +id: GO:0015494 +name: aromatic amino acid:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in)." [TC:2.A.3.1.3] +synonym: "aromatic amino acid:hydrogen symporter activity" EXACT [] +is_a: GO:0005280 ! amino acid:proton symporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity + +[Term] +id: GO:0015495 +name: gamma-aminobutyric acid:proton symporter activity +namespace: molecular_function +alt_id: GO:0005331 +alt_id: GO:0015329 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in)." [TC:2.A.18.5.1, TC:2.A.3.1.4, TC:2.A.3.4.2] +comment: See also the molecular function term 'neurotransmitter transporter activity ; GO:0005326'. +synonym: "4-aminobutanoate:hydrogen symporter activity" EXACT [] +synonym: "4-aminobutanoate:proton symporter activity" EXACT [] +synonym: "4-aminobutyrate:hydrogen symporter activity" EXACT [] +synonym: "4-aminobutyrate:proton symporter activity" EXACT [] +synonym: "GABA:hydrogen symporter activity" EXACT [] +synonym: "GABA:proton symporter activity" EXACT [] +synonym: "gamma-aminobutyric acid permease activity" EXACT [] +synonym: "gamma-aminobutyric acid:hydrogen symporter activity" EXACT [] +xref: Reactome:R-HSA-428625 "Vesicular inhibitory amino acid transport" +is_a: GO:0005280 ! amino acid:proton symporter activity +is_a: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity + +[Term] +id: GO:0015496 +name: putrescine:ornithine antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out)." [TC:2.A.3.2.1] +synonym: "putrescine-ornithine antiporter activity" EXACT [] +synonym: "putrescine/ornithine antiporter activity" EXACT [] +synonym: "putrescine:hydrogen symporter activity" EXACT [] +is_a: GO:0000064 ! L-ornithine transmembrane transporter activity +is_a: GO:0015489 ! putrescine transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:0140323 ! solute:anion antiporter activity + +[Term] +id: GO:0015498 +name: pantothenate:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in)." [TC:2.A.21.1.1] +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +is_a: GO:0140161 ! monocarboxylate:sodium symporter activity +relationship: part_of GO:0098719 ! sodium ion import across plasma membrane + +[Term] +id: GO:0015499 +name: formate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015659 +def: "Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [GOC:ai] +synonym: "formate uptake permease activity" EXACT [] +synonym: "formate uptake transmembrane transporter activity" RELATED [] +xref: RHEA:29679 +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015724 ! formate transport + +[Term] +id: GO:0015500 +name: obsolete threonine/serine:sodium symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in)." [TC:2.A.23.4.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "threonine/serine:sodium symporter activity" EXACT [] +is_obsolete: true +consider: GO:0005283 +consider: GO:0015194 +consider: GO:0015195 + +[Term] +id: GO:0015501 +name: glutamate:sodium symporter activity +namespace: molecular_function +alt_id: GO:0008027 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in)." [TC:2.A.27.1.1] +synonym: "sodium/excitatory glutamate cotransporter activity" BROAD [] +synonym: "sodium/excitatory glutamate symporter activity" EXACT [] +xref: RHEA:29031 +is_a: GO:0005283 ! amino acid:sodium symporter activity +is_a: GO:0017153 ! sodium:dicarboxylate symporter activity + +[Term] +id: GO:0015503 +name: glutathione-regulated potassium exporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state." [PMID:11053405, TC:2.A.37.1.1, TC:2.A.37.1.2] +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015504 +name: cytosine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in)." [TC:2.A.39.1.1] +synonym: "cytosine permease activity" RELATED [] +synonym: "cytosine:hydrogen ion symporter activity" EXACT [] +is_a: GO:0015209 ! cytosine transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015391 ! nucleobase:cation symporter activity + +[Term] +id: GO:0015505 +name: uracil:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in)." [GOC:mtg_transport] +synonym: "uracil permease activity" RELATED [] +is_a: GO:0015210 ! uracil transmembrane transporter activity +is_a: GO:0015391 ! nucleobase:cation symporter activity + +[Term] +id: GO:0015506 +name: nucleoside:proton symporter activity +namespace: molecular_function +alt_id: GO:0015536 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in)." [TC:2.A.1.10.1, TC:2.A.41.1.1] +synonym: "nucleoside permease activity" RELATED [] +synonym: "nucleoside:hydrogen ion symporter activity" EXACT [] +synonym: "nucleoside:hydrogen symporter activity" EXACT [] +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0015507 +name: obsolete hydroxy/aromatic amino acid permease activity +namespace: molecular_function +def: "OBSOLETE. Permease for hydroxy and aromatic amino acids." [GOC:ai] +comment: This term was made obsolete because it is a redundant grouping term. +synonym: "hydroxy/aromatic amino acid permease activity" EXACT [] +is_obsolete: true +consider: GO:0015171 +consider: GO:0015173 + +[Term] +id: GO:0015513 +name: high-affinity secondary active nitrite transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport, ISBN:0815340729] +synonym: "nitrite uptake permease activity" EXACT [] +is_a: GO:0015112 ! nitrate transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015514 +name: nitrite efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "nitrite extrusion permease activity" EXACT [] +is_a: GO:0015113 ! nitrite transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015515 +name: citrate:succinate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out)." [TC:2.A.47.3.2] +is_a: GO:0015141 ! succinate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0071913 ! citrate secondary active transmembrane transporter activity + +[Term] +id: GO:0015516 +name: tartrate:succinate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out)." [TC:2.A.47.3.3] +is_a: GO:0015141 ! succinate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015554 ! tartrate transmembrane transporter activity + +[Term] +id: GO:0015517 +name: galactose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in)." [TC:2.A.1.1.1, TC:2.A.1.1.9] +synonym: "galactose:hydrogen symporter activity" EXACT [] +synonym: "lactose, galactose:hydrogen symporter activity" BROAD [] +is_a: GO:0005354 ! galactose transmembrane transporter activity +is_a: GO:0009679 ! hexose:proton symporter activity + +[Term] +id: GO:0015518 +name: arabinose:proton symporter activity +namespace: molecular_function +alt_id: GO:0015523 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in)." [TC:2.A.1.1.2] +synonym: "arabinose efflux permease activity" BROAD [] +synonym: "arabinose efflux transmembrane transporter activity" BROAD [] +synonym: "arabinose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0042900 ! arabinose transmembrane transporter activity + +[Term] +id: GO:0015519 +name: D-xylose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in)." [TC:2.A.1.1.3] +synonym: "D-xylose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015148 ! D-xylose transmembrane transporter activity + +[Term] +id: GO:0015520 +name: tetracycline:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out)." [TC:2.A.1.2.4] +synonym: "tetracyclin:hydrogen antiporter activity" EXACT [] +synonym: "tetracyclin:proton antiporter activity" EXACT [] +synonym: "tetracycline:hydrogen antiporter activity" EXACT [] +is_a: GO:0008493 ! tetracycline transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity + +[Term] +id: GO:0015521 +name: obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in)." [TC:2.A.1.2.7] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" EXACT [] +synonym: "bicyclomycin/sulfathiazole:proton antiporter activity" EXACT [] +synonym: "bicyclomycin/sulphathiazole:hydrogen antiporter activity" EXACT [] +is_obsolete: true +consider: GO:0015545 +consider: GO:0015546 +consider: GO:0045119 + +[Term] +id: GO:0015522 +name: obsolete hydrophobic uncoupler:proton antiporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS." [TC:2.A.1.2.9] +comment: The reason for obsoletion is that this term represented a specific protein in TCDB, 2.A.1.2.9, which actually is a sugar transporter that seems to also function as a multidrug efflux protein. +synonym: "hydrophobic uncoupler:hydrogen antiporter activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015524 +name: obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out)." [TC:2.A.1.2.15] +comment: This term was made obsolete because it represents a gene product rather than a single discrete molecular function. +synonym: "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity" EXACT [] +synonym: "L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity" EXACT [] +is_obsolete: true +consider: GO:0015147 +consider: GO:0015299 +consider: GO:0051119 + +[Term] +id: GO:0015525 +name: obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" EXACT [] +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity" EXACT [] +is_obsolete: true +consider: GO:0015547 +consider: GO:0015548 +consider: GO:0015549 + +[Term] +id: GO:0015526 +name: hexose-phosphate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.1] +is_a: GO:0015119 ! hexose phosphate transmembrane transporter activity +is_a: GO:0015315 ! organophosphate:inorganic phosphate antiporter activity + +[Term] +id: GO:0015527 +name: glycerol-phosphate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.3] +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity +is_a: GO:0015168 ! glycerol transmembrane transporter activity +is_a: GO:0140323 ! solute:anion antiporter activity + +[Term] +id: GO:0015528 +name: lactose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in)." [TC:2.A.1.1.9, TC:2.A.1.5.1] +synonym: "lactose, galactose:hydrogen symporter activity" BROAD [] +synonym: "lactose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015155 ! lactose transmembrane transporter activity + +[Term] +id: GO:0015529 +name: raffinose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in)." [TC:2.A.1.5.2] +synonym: "raffinose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015158 ! raffinose transmembrane transporter activity + +[Term] +id: GO:0015530 +name: shikimate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids." [GOC:ai] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0015733 ! shikimate transmembrane transport + +[Term] +id: GO:0015531 +name: citrate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in)." [TC:2.A.1.6.1] +synonym: "citrate:hydrogen symporter activity" EXACT [] +xref: RHEA:32123 +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0071913 ! citrate secondary active transmembrane transporter activity + +[Term] +id: GO:0015532 +name: alpha-ketoglutarate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in)." [TC:2.A.1.6.2] +synonym: "2-oxoglutarate:hydrogen symporter activity" EXACT [] +synonym: "2-oxoglutarate:proton symporter activity" EXACT [] +synonym: "alpha-ketoglutarate:hydrogen symporter activity" EXACT [] +is_a: GO:0015139 ! alpha-ketoglutarate transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0015533 +name: shikimate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in)." [TC:2.A.1.6.6] +synonym: "shikimate:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +is_a: GO:0015530 ! shikimate transmembrane transporter activity + +[Term] +id: GO:0015534 +name: obsolete proline/glycine/betaine:hydrogen/sodium symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in)." [TC:2.A.1.6.4] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" EXACT [] +synonym: "proline/glycine/betaine:proton/sodium symporter" EXACT [] +is_obsolete: true +consider: GO:0015187 +consider: GO:0015193 +consider: GO:0015199 +consider: GO:0015294 +consider: GO:0015295 +consider: GO:0015370 + +[Term] +id: GO:0015535 +name: fucose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in)." [TC:2.A.1.7.1] +synonym: "fucose:hydrogen symporter activity" EXACT [] +xref: RHEA:29023 +is_a: GO:0009679 ! hexose:proton symporter activity +is_a: GO:0015150 ! fucose transmembrane transporter activity + +[Term] +id: GO:0015537 +name: xanthosine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in)." [TC:2.A.1.10.2] +synonym: "xanthosine permease activity" RELATED [] +synonym: "xanthosine:hydrogen ion symporter activity" EXACT [] +is_a: GO:0015506 ! nucleoside:proton symporter activity +is_a: GO:0015553 ! xanthosine transmembrane transporter activity + +[Term] +id: GO:0015538 +name: sialic acid:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in)." [TC:2.A.1.12.1] +synonym: "sialic acid permease activity" RELATED [] +synonym: "sialic acid:hydrogen symporter activity" EXACT [] +xref: Reactome:R-HSA-428585 "SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-5624239 "Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol" +is_a: GO:0015136 ! sialic acid transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0015539 +name: hexuronate:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate." [TC:2.A.1.14.2] +synonym: "hexuronate (glucuronate/galacturonate) porter activity" NARROW [] +synonym: "hexuronate porter activity" RELATED [] +is_a: GO:0005402 ! carbohydrate:cation symporter activity +is_a: GO:0015134 ! hexuronate transmembrane transporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity + +[Term] +id: GO:0015540 +name: 3-hydroxyphenyl propionate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in)." [TC:2.A.1.15.2] +synonym: "3-hydroxyphenyl propionate porter activity" RELATED [] +synonym: "3-hydroxyphenyl propionate:hydrogen ion symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015551 ! 3-hydroxyphenyl propanoate transmembrane transporter activity + +[Term] +id: GO:0015541 +name: secondary active cyanate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cyanate from one side of a membrane to the other." [TC:2.A.1.17.1] +synonym: "cyanate porter activity" RELATED [] +is_a: GO:0015110 ! cyanate transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0015543 +name: obsolete lactose/glucose efflux transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out)." [TC:2.A.1.20.2] +comment: This term was made obsolete because it represents two molecular functions. +synonym: "lactose/glucose efflux transporter activity" EXACT [] +is_obsolete: true +consider: GO:0015155 + +[Term] +id: GO:0015544 +name: phenyl propionate uniporter activity +namespace: molecular_function +def: "Enables the transfer of phenyl propionate from one side of a membrane to the other." [GOC:mtg_transport, TC:2.A.1.27.1] +synonym: "phenyl propionate permease activity" RELATED [] +is_a: GO:0015292 ! uniporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +is_a: GO:0015552 ! propionate transmembrane transporter activity + +[Term] +id: GO:0015545 +name: bicyclomycin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive." [ISBN:091191028X] +synonym: "bicyclomycin transporter activity" RELATED [] +synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015905 ! bicyclomycin transmembrane transport + +[Term] +id: GO:0015546 +name: sulfathiazole transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group." [GOC:curators] +synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" RELATED [] +synonym: "sulphathiazole transporter activity" EXACT [] +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:1902599 ! sulfathiazole transmembrane transport + +[Term] +id: GO:0015547 +name: nalidixic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication." [GOC:curators, PMID:12702699, PubChem_Compound:4221] +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" RELATED [] +synonym: "nalidixic acid transporter activity" RELATED [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0015896 ! nalidixic acid transport + +[Term] +id: GO:0015548 +name: organomercurial transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom." [GOC:ai, PMID:18793329] +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] +synonym: "organomercurial transporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015897 ! organomercurial transport + +[Term] +id: GO:0015549 +name: carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes." [GOC:curators] +synonym: "carbonyl cyanide m-chlorophenylhydrazone transporter activity" RELATED [] +synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" RELATED [] +synonym: "CCCP transporter activity" EXACT [] +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0015902 ! carbonyl cyanide m-chlorophenylhydrazone transport + +[Term] +id: GO:0015550 +name: galacturonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:ai] +is_a: GO:0015134 ! hexuronate transmembrane transporter activity +relationship: part_of GO:0015737 ! galacturonate transmembrane transport + +[Term] +id: GO:0015551 +name: 3-hydroxyphenyl propanoate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other." [GOC:ai] +synonym: "3-hydroxyphenyl propionate transmembrane transporter activity" EXACT [] +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0015731 ! 3-hydroxyphenyl propanoate transport + +[Term] +id: GO:0015552 +name: propionate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH." [GOC:ai] +is_a: GO:0015636 ! short-chain fatty acid transmembrane transporter activity +relationship: part_of GO:0015730 ! propanoate transport + +[Term] +id: GO:0015553 +name: xanthosine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other." [ISBN:0198506732] +is_a: GO:0015211 ! purine nucleoside transmembrane transporter activity +relationship: part_of GO:0015863 ! xanthosine transport + +[Term] +id: GO:0015554 +name: tartrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria." [GOC:ai] +is_a: GO:1901702 ! salt transmembrane transporter activity + +[Term] +id: GO:0015556 +name: C4-dicarboxylate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of C4-dicarboxylate from one side of a membrane to the other." [GOC:krc] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:0015740 ! C4-dicarboxylate transport + +[Term] +id: GO:0015558 +name: secondary active p-aminobenzoyl-glutamate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015569 +def: "Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid." [GOC:ai] +synonym: "p-aminobenzoyl-glutamate transmembrane transporter activity" NARROW [] +synonym: "p-aminobenzoyl-glutamate transporter activity" RELATED [] +synonym: "p-aminobenzoyl-glutamate uptake permease activity" RELATED [] +synonym: "p-aminobenzoyl-glutamate uptake transmembrane transporter activity" RELATED [] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +is_a: GO:0071916 ! dipeptide transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity + +[Term] +id: GO:0015560 +name: obsolete L-idonate/D-gluconate:hydrogen symporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in)." [TC:2.A.8.1.2] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "L-idonate/D-gluconate:hydrogen symporter activity" EXACT [] +synonym: "L-idonate/D-gluconate:proton symporter" EXACT [] +is_obsolete: true +consider: GO:0015128 +consider: GO:0015295 +consider: GO:0015568 + +[Term] +id: GO:0015561 +name: rhamnose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in)." [TC:2.A.7.6.1] +synonym: "rhamnose:hydrogen symporter activity" EXACT [] +is_a: GO:0009679 ! hexose:proton symporter activity +is_a: GO:0015153 ! rhamnose transmembrane transporter activity + +[Term] +id: GO:0015562 +name: efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "efflux permease activity" EXACT [] +synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0015565 +name: threonine efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "threonine efflux permease activity" EXACT [] +synonym: "threonine export protein" RELATED [] +synonym: "threonine export transporter activity" EXACT [] +is_a: GO:0015195 ! L-threonine transmembrane transporter activity +is_a: GO:0034639 ! L-amino acid efflux transmembrane transporter activity + +[Term] +id: GO:0015566 +name: acriflavine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015555 +def: "Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication." [PubChem_Compound:6842] +synonym: "acriflavin resistant pump activity" RELATED [GOC:dph, GOC:tb] +synonym: "acriflavin transporter activity" RELATED [GOC:dph, GOC:tb] +synonym: "acriflavine transporter activity" RELATED [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015108 ! chloride transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1901702 ! salt transmembrane transporter activity +relationship: part_of GO:0015894 ! acriflavine transport + +[Term] +id: GO:0015567 +name: alkane transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds." [GOC:ai] +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0015895 ! alkane transport + +[Term] +id: GO:0015568 +name: L-idonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:ai] +synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] +is_a: GO:0042879 ! aldonate transmembrane transporter activity +relationship: part_of GO:0015726 ! L-idonate transmembrane transport + +[Term] +id: GO:0015571 +name: N-acetylgalactosamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015590 +def: "Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "N-acetylgalactosamine permease activity" EXACT [] +is_a: GO:0019196 ! galactosamine transmembrane transporter activity +relationship: part_of GO:0015763 ! N-acetylgalactosamine transport + +[Term] +id: GO:0015572 +name: N-acetylglucosamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015580 +def: "Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "D-GlcNAc transmembrane transporter activity" EXACT [] +synonym: "N-Acetyl-D-glucosamine permease" RELATED [] +synonym: "N-acetyl-D-glucosamine transmembrane transporter activity" EXACT [] +synonym: "N-acetylchitosamine transmembrane transporter activity" EXACT [] +synonym: "N-acetylglucosamine permease activity" RELATED [] +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity + +[Term] +id: GO:0015573 +name: beta-glucoside transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015582 +def: "Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration." [GOC:jl, GOC:mtg_transport, http://www.biochem.purdue.edu/, ISBN:0198506732, ISBN:0815340729] +synonym: "beta-glucoside permease activity" EXACT [] +is_a: GO:0042947 ! glucoside transmembrane transporter activity +relationship: part_of GO:0015759 ! beta-glucoside transport + +[Term] +id: GO:0015574 +name: trehalose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015584 +def: "Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "trehalose permease activity" EXACT [] +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0015771 ! trehalose transport + +[Term] +id: GO:0015575 +name: mannitol transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015586 +def: "Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "mannitol permease activity" EXACT [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015797 ! mannitol transport + +[Term] +id: GO:0015576 +name: sorbitol transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015587 +def: "Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose." [GOC:ai, ISBN:0198506732] +synonym: "glucitol permease activity" EXACT [] +synonym: "glucitol transporter activity" EXACT [] +synonym: "sorbitol permease activity" EXACT [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +is_a: GO:0022804 ! active transmembrane transporter activity +relationship: part_of GO:0015795 ! sorbitol transport + +[Term] +id: GO:0015577 +name: galactitol transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015588 +def: "Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "galactitol permease activity" EXACT [] +xref: RHEA:33143 +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0015796 ! galactitol transport + +[Term] +id: GO:0015578 +name: mannose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015589 +def: "Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "mannose permease activity" EXACT [] +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015761 ! mannose transmembrane transport + +[Term] +id: GO:0015583 +name: obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because it arbitrarily groups three substrates. +synonym: "beta-glucoside [arbutin-salicin-cellobiose] permease activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0015591 +name: D-ribose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0015146 ! pentose transmembrane transporter activity +relationship: part_of GO:0015752 ! D-ribose transmembrane transport + +[Term] +id: GO:0015592 +name: methylgalactoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group." [GOC:mtg_transport, ISBN:0815340729] +synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015765 ! methylgalactoside transport + +[Term] +id: GO:0015593 +name: allose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015149 ! hexose transmembrane transporter activity +relationship: part_of GO:0015754 ! allose transmembrane transport + +[Term] +id: GO:0015594 +name: ATPase-coupled putrescine transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in)." [EC:7.6.2.11] +synonym: "putrescine porter activity" BROAD [] +synonym: "putrescine-importing ATPase activity" RELATED [] +xref: RHEA:29995 +is_a: GO:0015417 ! ATPase-coupled polyamine transmembrane transporter activity +is_a: GO:0015489 ! putrescine transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015595 +name: ATPase-coupled spermidine transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + spermidine(out) -> ADP + phosphate + spermidine(in)." [EC:3.6.3.31] +synonym: "spermidine porter activity" BROAD [] +synonym: "spermidine-importing ATPase activity" RELATED [] +xref: MetaCyc:ABC-24-RXN +xref: RHEA:29999 +is_a: GO:0015417 ! ATPase-coupled polyamine transmembrane transporter activity +is_a: GO:0015606 ! spermidine transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015596 +name: obsolete glycine betaine/proline porter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in)." [EC:3.6.3.32, TC:3.A.1.12.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "glycine betaine/proline porter activity" EXACT [] +is_obsolete: true +consider: GO:0015187 +consider: GO:0015193 +consider: GO:0015199 +consider: GO:0015418 + +[Term] +id: GO:0015597 +name: obsolete histidine/arginine/lysine/ornithine porter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)." [EC:3.6.3.21, TC:3.A.1.3.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "histidine/arginine/lysine/ornithine porter activity" EXACT [] +is_obsolete: true +consider: GO:0000064 +consider: GO:0005290 +consider: GO:0015181 +consider: GO:0015189 +consider: GO:0015426 + +[Term] +id: GO:0015599 +name: ATPase-coupled L-glutamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in)." [EC:7.4.2.1] +synonym: "ATPase-coupled glutamine transmembrane transporter activity" BROAD [] +synonym: "glutamine porter activity" BROAD [] +synonym: "glutamine-importing ATPase activity" RELATED [] +xref: EC:7.4.2.1 +xref: MetaCyc:ABC-12-RXN +is_a: GO:0015186 ! L-glutamine transmembrane transporter activity +is_a: GO:0015426 ! ATPase-coupled polar amino acid-transporter activity + +[Term] +id: GO:0015600 +name: obsolete glutamate/aspartate porter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)." [EC:3.6.3.21, TC:3.A.1.3.4] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "glutamate/aspartate porter activity" EXACT [] +is_obsolete: true +consider: GO:0005313 +consider: GO:0015183 +consider: GO:0015426 + +[Term] +id: GO:0015601 +name: obsolete cystine/diaminopimelate porter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)." [EC:3.6.3.21, TC:3.A.1.3.10] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "cystine/diaminopimelate porter activity" EXACT [] +is_obsolete: true +consider: GO:0015184 +consider: GO:0015426 +consider: GO:0015626 + +[Term] +id: GO:0015602 +name: obsolete leucine/isoleucine/valine porter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in)." [EC:3.6.3.22, TC:3.A.1.4.1] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "leucine/isoleucine/valine porter activity" EXACT [] +is_obsolete: true +consider: GO:0005304 +consider: GO:0015188 +consider: GO:0015190 +consider: GO:0015425 + +[Term] +id: GO:0015603 +name: iron chelate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions." [PMID:17660286] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0033214 ! siderophore-dependent iron import into cell + +[Term] +id: GO:0015604 +name: organic phosphonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of phosphonate from one side of a membrane to the other. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)." [GOC:ai] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015716 ! organic phosphonate transport + +[Term] +id: GO:0015605 +name: organophosphate ester transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds." [GOC:mcc] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015748 ! organophosphate ester transport + +[Term] +id: GO:0015606 +name: spermidine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015203 ! polyamine transmembrane transporter activity +relationship: part_of GO:1903711 ! spermidine transmembrane transport + +[Term] +id: GO:0015607 +name: ATPase-coupled fatty-acyl-CoA transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it." [EC:7.6.2.4] +synonym: "ABC-type fatty-acyl-CoA transporter" EXACT [EC:7.6.2.4] +synonym: "fatty acyl CoA transporter activity" EXACT [] +synonym: "fatty-acyl-CoA transmembrane transporter activity" BROAD [] +synonym: "fatty-acyl-CoA-transporting ATPase" EXACT [EC:7.6.2.4] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0033220 ! ATPase-coupled amide-transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:0071077 ! adenosine 3',5'-bisphosphate transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0015916 ! fatty-acyl-CoA transport + +[Term] +id: GO:0015608 +name: carbohydrate-importing ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in)." [GOC:ai, TC:3.A.1.1.-, TC:3.A.1.2.-] +synonym: "carbohydrate uptake transporter activity" EXACT [] +synonym: "sugar transporter" NARROW [] +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0015611 +name: D-ribose-importing ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in)." [EC:3.6.3.17, TC:3.A.1.-.-] +synonym: "D-ribose porter activity" BROAD [] +xref: MetaCyc:ABC-28-RXN +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity +is_a: GO:0015591 ! D-ribose transmembrane transporter activity +is_a: GO:0015608 ! carbohydrate-importing ATPase activity + +[Term] +id: GO:0015612 +name: L-arabinose-importing ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in)." [EC:3.6.3.17, TC:3.A.1.-.-] +synonym: "L-arabinose porter activity" EXACT [] +xref: MetaCyc:ABC-2-RXN +is_a: GO:0015147 ! L-arabinose transmembrane transporter activity +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity +is_a: GO:0015608 ! carbohydrate-importing ATPase activity + +[Term] +id: GO:0015613 +name: obsolete galactose/glucose (methylgalactoside) porter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a multifunctional gene product. +synonym: "galactose/glucose (methylgalactoside) porter activity" EXACT [] +is_obsolete: true +consider: GO:0005354 +consider: GO:0005355 +consider: GO:0015291 +consider: GO:0015592 + +[Term] +id: GO:0015614 +name: ATPase-coupled D-xylose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in)." [RHEA:29902] +synonym: "D-xylose porter activity" BROAD [] +synonym: "D-xylose-importing ATPase activity" RELATED [] +xref: RHEA:29902 +is_a: GO:0015148 ! D-xylose transmembrane transporter activity +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity + +[Term] +id: GO:0015615 +name: D-allose-importing ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in)." [TC:3.A.1.-.-] +synonym: "D-allose porter activity" BROAD [] +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity +is_a: GO:0015593 ! allose transmembrane transporter activity + +[Term] +id: GO:0015616 +name: DNA translocase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule." [GOC:mah, PMID:16428451, PMID:17631491] +comment: Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane. +is_a: GO:0008094 ! DNA-dependent ATPase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: has_part GO:0003677 ! DNA binding + +[Term] +id: GO:0015617 +name: obsolete pilin/fimbrilin exporter activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "pilin/fimbrilin exporter activity" EXACT [] +is_obsolete: true +consider: GO:0015462 + +[Term] +id: GO:0015620 +name: ferric-enterobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferric-enterobactin from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015343 ! siderophore transmembrane transporter activity +relationship: part_of GO:0015685 ! ferric-enterobactin import into cell + +[Term] +id: GO:0015621 +name: ferric triacetylfusarinine C transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other." [GOC:ai] +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0015623 +name: ATPase-coupled iron-chelate transporter activity +namespace: molecular_function +alt_id: GO:0015409 +alt_id: GO:0102026 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + iron chelate(out) = ADP + phosphate + iron chelate(in). Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores are imported." [EC:7.2.2.16] +synonym: "ATP phosphohydrolase (iron-chelate-importing)" EXACT [EC:7.2.2.16] +synonym: "ATP-dependent iron-chelate transporter activity" EXACT [] +synonym: "ferric dicitrate transporter activity" NARROW [] +synonym: "ferric/ferric-dicitrate porter" BROAD [] +synonym: "iron-chelate ABC transporter" NARROW [] +synonym: "iron-chelate-transporting ATPase activity" EXACT [] +xref: EC:7.2.2.16 +xref: MetaCyc:3.6.3.34-RXN +xref: MetaCyc:ABC-9-RXN +is_a: GO:0015603 ! iron chelate transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0015624 +name: ATPase-coupled ferric-enterobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in)." [EC:7.2.2.17] +synonym: "ATP-dependent ferric-enterobactin transmembrane transporter activity" EXACT [] +synonym: "ferric-enterobactin ABC transporter" NARROW [] +synonym: "ferric-enterobactin porter activity" BROAD [] +synonym: "ferric-enterobactin-transporting ATPase activity" EXACT [] +xref: MetaCyc:ABC-10-RXN +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015623 ! ATPase-coupled iron-chelate transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity + +[Term] +id: GO:0015625 +name: ATPase-coupled ferric-hydroxamate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015622 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in)." [EC:7.2.2.16] +synonym: "ATP-dependent ferric-hydroxamate transmembrane transporter activity" EXACT [] +synonym: "ferric-hydroxamate ABC transporter" NARROW [] +synonym: "ferric-hydroxamate porter activity" BROAD [] +synonym: "ferric-hydroxamate transmembrane transporter activity" BROAD [] +synonym: "ferric-hydroxamate-transporting ATPase activity" EXACT [] +xref: EC:7.2.2.16 +xref: MetaCyc:ABC-11-RXN +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015623 ! ATPase-coupled iron-chelate transporter activity +is_a: GO:0033220 ! ATPase-coupled amide-transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015626 +name: L-diaminopimelate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid." [GOC:go_curators, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "cystine/diaminopimelate porter activity" NARROW [] +synonym: "L-diaminopimelate transporter activity" BROAD [] +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0015830 ! diaminopimelate transport + +[Term] +id: GO:0015627 +name: type II protein secretion system complex +namespace: cellular_component +def: "A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex." [PMID:16448494] +comment: Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'. +synonym: "general secretion pathway-associated complex" RELATED [] +synonym: "main terminal branch" EXACT [] +synonym: "MTB" EXACT [] +synonym: "Sec-dependent secretion system-associated complex" RELATED [] +synonym: "T2SS-associated complexes" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0015628 +name: protein secretion by the type II secretion system +namespace: biological_process +def: "The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type II protein secretion system complex ; GO:0015627'. This process refers specifically to secretion across the outer membrane. For components of the Sec and Tat pathways, consider annotating to 'protein transport by the Sec complex ; GO:0043952' and 'protein transport by the Tat complex ; GO:0043953'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted. +synonym: "protein secretion by the general secretion pathway" RELATED [] +synonym: "protein secretion by the general secretory pathway" RELATED [] +synonym: "protein secretion by the T2S" EXACT [] +synonym: "protein secretion by the T2SS" EXACT [] +synonym: "protein secretion by the type II protein secretion system" EXACT [] +synonym: "type II protein secretion system" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0098776 ! protein transport across the cell outer membrane + +[Term] +id: GO:0015629 +name: actin cytoskeleton +namespace: cellular_component +def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194] +subset: goslim_aspergillus +is_a: GO:0005856 ! cytoskeleton + +[Term] +id: GO:0015630 +name: microtubule cytoskeleton +namespace: cellular_component +def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] +subset: goslim_aspergillus +is_a: GO:0005856 ! cytoskeleton + +[Term] +id: GO:0015631 +name: tubulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules." [GOC:clt] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0015633 +name: ATPase-coupled zinc transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in)." [TC:3.A.1.-.-] +synonym: "ATP-dependent zinc transmembrane transporter activity" EXACT [] +synonym: "zinc porter activity" RELATED [] +synonym: "zinc transporting ATPase activity" RELATED [] +synonym: "zinc-transporting ATPase activity" EXACT [] +xref: RHEA:29795 +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +relationship: part_of GO:0071577 ! zinc ion transmembrane transport + +[Term] +id: GO:0015634 +name: obsolete lipopolysaccharide exporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was obsoleted because export is a process, not a function. +synonym: "LPS exporter activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17202 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0015636 +name: short-chain fatty acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015635 +def: "Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:mah] +synonym: "short-chain fatty acid transporter activity" RELATED [] +synonym: "short-chain fatty acid uptake transporter activity" RELATED [] +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +relationship: part_of GO:0015912 ! short-chain fatty acid transport + +[Term] +id: GO:0015638 +name: microcin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a microcin from one side of a membrane to the other." [GOC:mah] +synonym: "microcin uptake permease activity" EXACT [] +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0042884 ! microcin transport + +[Term] +id: GO:0015640 +name: peptidoglycan peptide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains." [ISBN:0198506732] +synonym: "murein peptide transporter activity" EXACT [] +synonym: "muropeptide transporter activity" EXACT [] +is_a: GO:0015647 ! peptidoglycan transmembrane transporter activity +relationship: part_of GO:0015834 ! peptidoglycan-associated peptide transport + +[Term] +id: GO:0015641 +name: obsolete lipoprotein toxin +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "lipoprotein toxin" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0015642 +name: obsolete bacteriolytic toxin activity +namespace: molecular_function +def: "OBSOLETE. Acts as to cause lysis of bacterial cells." [GOC:jl] +comment: This term was made obsolete because it represents a class of gene products and not a molecular function. +synonym: "bacteriolytic toxin activity" EXACT [] +is_obsolete: true +consider: GO:0019835 + +[Term] +id: GO:0015643 +name: toxic substance binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems." [GOC:bf, GOC:curators, GOC:jl, GOC:pr] +synonym: "antitoxin activity" RELATED [] +synonym: "lipoprotein antitoxin" RELATED [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0015644 +name: obsolete lipoprotein antitoxin +namespace: molecular_function +def: "OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it." [GOC:jl] +comment: This term was made obsolete because it does not represent a function distinct from its parent term. +synonym: "lipoprotein antitoxin" EXACT [] +is_obsolete: true +replaced_by: GO:0015643 + +[Term] +id: GO:0015645 +name: fatty acid ligase activity +namespace: molecular_function +def: "Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP." [EC:6.2.1.3, GOC:cjk, GOC:mah] +synonym: "acid:CoA ligase (AMP-forming) activity" EXACT [EC:6.2.1.3] +synonym: "acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.3] +synonym: "acyl-coenzyme A ligase activity" EXACT [EC:6.2.1.3] +synonym: "fatty acid CoA ligase activity" EXACT [EC:6.2.1.3] +synonym: "fatty acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.3] +synonym: "fatty-acid ligase activity" EXACT [] +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0015647 +name: peptidoglycan transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other." [GOC:ai] +synonym: "murein transporter activity" EXACT [] +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0015835 ! peptidoglycan transport + +[Term] +id: GO:0015648 +name: lipid-linked peptidoglycan transporter activity +namespace: molecular_function +def: "Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells." [GOC:mah] +synonym: "lipid-linked murein transporter activity" EXACT [] +is_a: GO:0015647 ! peptidoglycan transmembrane transporter activity +relationship: part_of GO:0015836 ! lipid-linked peptidoglycan transport + +[Term] +id: GO:0015649 +name: 2-keto-3-deoxygluconate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in)." [TC:2.A.10.1.1] +synonym: "2-keto-3-deoxygluconate:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015145 ! monosaccharide transmembrane transporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +is_a: GO:0042879 ! aldonate transmembrane transporter activity +relationship: part_of GO:0046411 ! 2-keto-3-deoxygluconate transmembrane transport + +[Term] +id: GO:0015650 +name: lactate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in)." [TC:2.A.14.1.1] +synonym: "lactate permease" BROAD [] +synonym: "lactate:hydrogen porter activity" EXACT [] +synonym: "lactate:hydrogen symporter activity" EXACT [] +synonym: "lactate:proton porter activity" EXACT [] +is_a: GO:0015129 ! lactate transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity + +[Term] +id: GO:0015651 +name: quaternary ammonium group transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015202 +def: "Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups." [ISBN:0198506732] +synonym: "quaternary amine transmembrane transporter activity" EXACT [] +synonym: "quaternary ammonium compound transporter activity" EXACT [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +relationship: part_of GO:0015697 ! quaternary ammonium group transport + +[Term] +id: GO:0015652 +name: quaternary ammonium group:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in)." [GOC:ai] +synonym: "quaternary ammonium group:hydrogen symporter activity" EXACT [] +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity + +[Term] +id: GO:0015653 +name: glycine betaine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in)." [TC:2.A.15.1.1] +synonym: "glycine betaine:hydrogen symporter activity" EXACT [] +is_a: GO:0015199 ! amino-acid betaine transmembrane transporter activity +is_a: GO:0015652 ! quaternary ammonium group:proton symporter activity +relationship: part_of GO:0031460 ! glycine betaine transport + +[Term] +id: GO:0015654 +name: tellurite transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015118 +def: "Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals." [GOC:ai] +synonym: "tellurite uptake transmembrane transporter activity" RELATED [] +synonym: "tellurite-resistance uptake permease activity" RELATED [] +synonym: "tellurite-resistance uptake transmembrane transporter activity" RELATED [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity + +[Term] +id: GO:0015655 +name: alanine:sodium symporter activity +namespace: molecular_function +alt_id: GO:0044670 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in)." [GOC:ai] +synonym: "sodium:alanine symporter activity" EXACT [] +xref: RHEA:29283 +is_a: GO:0005283 ! amino acid:sodium symporter activity +is_a: GO:0022858 ! alanine transmembrane transporter activity +created_by: jl +creation_date: 2012-08-08T12:57:30Z + +[Term] +id: GO:0015657 +name: branched-chain amino acid:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in)." [TC:2.A.26.1.1] +is_a: GO:0005283 ! amino acid:sodium symporter activity +is_a: GO:0015658 ! branched-chain amino acid transmembrane transporter activity +is_a: GO:0140323 ! solute:anion antiporter activity + +[Term] +id: GO:0015658 +name: branched-chain amino acid transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901240 +def: "Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings." [GOC:ai, GOC:bf, GOC:mtg_transport, ISBN:0815340729] +synonym: "branched-chain aliphatic amino acid transmembrane transporter activity" EXACT [GOC:bf] +synonym: "branched-chain aliphatic amino acid transporter activity" EXACT [] +synonym: "leucine/valine/isoleucine permease activity" RELATED [] +synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0015803 ! branched-chain amino acid transport + +[Term] +id: GO:0015660 +name: formate efflux transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015509 +def: "Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "formate efflux permease activity" RELATED [] +is_a: GO:0015499 ! formate transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity + +[Term] +id: GO:0015661 +name: L-lysine efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "L-lysine exporter activity" EXACT [] +synonym: "L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity" EXACT [] +is_a: GO:0015189 ! L-lysine transmembrane transporter activity +is_a: GO:0034639 ! L-amino acid efflux transmembrane transporter activity + +[Term] +id: GO:0015662 +name: ion transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate." [PMID:10322420, PMID:10600683] +synonym: "ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism" EXACT [] +synonym: "P-type ATPase activity" EXACT [] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] +xref: Reactome:R-HSA-429157 "ABCC4 accumulation of dense granule contents" +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0015663 +name: nicotinamide mononucleotide transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015664 +def: "Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP." [ISBN:0721662544] +synonym: "nicotinamide mononucleotide permease activity" RELATED [] +synonym: "nicotinamide ribonucleotide transmembrane transporter activity" EXACT [] +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0035353 ! nicotinamide mononucleotide transmembrane transport + +[Term] +id: GO:0015665 +name: alcohol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group." [ISBN:0198506732] +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity + +[Term] +id: GO:0015666 +name: restriction endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mlg] +synonym: "restriction endonuclease activity" EXACT [] +synonym: "restriction enzyme activity" EXACT [] +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0015667 +name: site-specific DNA-methyltransferase (cytosine-N4-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine." [EC:2.1.1.113] +synonym: "DNA[cytosine-N4]methyltransferase activity" EXACT [EC:2.1.1.113] +synonym: "m4C-forming MTase activity" EXACT [EC:2.1.1.113] +synonym: "modification methylase activity" RELATED [EC:2.1.1.113] +synonym: "N(4)-cytosine-specific DNA methylase activity" EXACT [EC:2.1.1.113] +synonym: "N4-cytosine-specific DNA methylase activity" EXACT [EC:2.1.1.113] +synonym: "restriction-modification system activity" RELATED [EC:2.1.1.113] +synonym: "S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity" EXACT [EC:2.1.1.113] +synonym: "S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity" EXACT [EC:2.1.1.113] +xref: EC:2.1.1.113 +xref: MetaCyc:2.1.1.113-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0009008 ! DNA-methyltransferase activity +relationship: part_of GO:0090124 ! N-4 methylation of cytosine + +[Term] +id: GO:0015668 +name: type III site-specific deoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites." [EC:3.1.21.5, PMID:12654995] +synonym: "type III restriction enzyme activity" EXACT [] +xref: EC:3.1.21.5 +xref: MetaCyc:3.1.21.5-RXN +is_a: GO:0015666 ! restriction endodeoxyribonuclease activity +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0015669 +name: gas transport +namespace: biological_process +def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +is_a: GO:0006810 ! transport + +[Term] +id: GO:0015670 +name: carbon dioxide transport +namespace: biological_process +def: "The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015669 ! gas transport +is_a: GO:0015893 ! drug transport +is_a: GO:0019755 ! one-carbon compound transport + +[Term] +id: GO:0015671 +name: oxygen transport +namespace: biological_process +def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015669 ! gas transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0015672 +name: monovalent inorganic cation transport +namespace: biological_process +def: "The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage." [GOC:ai] +is_a: GO:0006812 ! cation transport + +[Term] +id: GO:0015673 +name: silver ion transport +namespace: biological_process +def: "The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "silver transport" EXACT [] +is_a: GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0015675 +name: nickel cation transport +namespace: biological_process +def: "The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0015676 +name: vanadium ion transport +namespace: biological_process +def: "The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0015677 +name: copper ion import +namespace: biological_process +def: "The directed movement of copper ions into a cell or organelle." [GOC:ai] +synonym: "copper ion uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006825 ! copper ion transport + +[Term] +id: GO:0015679 +name: plasma membrane copper ion transport +namespace: biological_process +def: "The directed movement of copper ions across the plasma membrane." [GOC:ai] +synonym: "plasma membrane copper transport" EXACT [] +is_a: GO:0035434 ! copper ion transmembrane transport + +[Term] +id: GO:0015680 +name: protein maturation by copper ion transfer +namespace: biological_process +def: "A process that contributes to the delivery of copper ions to a target protein." [GOC:ai] +synonym: "intracellular copper delivery" EXACT [] +synonym: "intracellular copper ion delivery" RELATED [] +synonym: "intracellular copper ion transport" BROAD [] +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0015685 +name: ferric-enterobactin import into cell +namespace: biological_process +def: "A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors." [GOC:pg, PMID:23192658] +synonym: "ferric-enterobactin transport" BROAD [] +is_a: GO:0033214 ! siderophore-dependent iron import into cell +is_a: GO:0042930 ! enterobactin transport + +[Term] +id: GO:0015686 +name: ferric triacetylfusarinine C import into cell +namespace: biological_process +def: "The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "ferric triacetylfusarinine C transport" BROAD [] +is_a: GO:0033214 ! siderophore-dependent iron import into cell +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015687 +name: ferric-hydroxamate import into cell +namespace: biological_process +def: "A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors." [GOC:pg, PMID:23192658] +synonym: "ferric-hydroxamate transport" BROAD [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0033214 ! siderophore-dependent iron import into cell +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0015689 +name: molybdate ion transport +namespace: biological_process +def: "The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid." [GOC:ai] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015690 +name: aluminum cation transport +namespace: biological_process +def: "The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "aluminium ion transport" EXACT [] +synonym: "aluminium transport" EXACT [] +synonym: "aluminum ion transport" RELATED [] +synonym: "aluminum transport" EXACT [] +is_a: GO:0030001 ! metal ion transport +is_a: GO:0072512 ! trivalent inorganic cation transport + +[Term] +id: GO:0015691 +name: cadmium ion transport +namespace: biological_process +def: "The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "cadmium transport" EXACT [] +is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0070838 ! divalent metal ion transport + +[Term] +id: GO:0015692 +name: lead ion transport +namespace: biological_process +def: "The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0030001 ! metal ion transport + +[Term] +id: GO:0015693 +name: magnesium ion transport +namespace: biological_process +def: "The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "magnesium transport" RELATED [] +is_a: GO:0070838 ! divalent metal ion transport + +[Term] +id: GO:0015694 +name: mercury ion transport +namespace: biological_process +def: "The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "mercuric ion transport" NARROW [] +synonym: "mercury transport" EXACT [] +is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0072511 ! divalent inorganic cation transport +relationship: part_of GO:0050787 ! detoxification of mercury ion + +[Term] +id: GO:0015695 +name: organic cation transport +namespace: biological_process +def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] +is_a: GO:0006812 ! cation transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015696 +name: ammonium transport +namespace: biological_process +def: "The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals." [ISBN:0198506732] +synonym: "ammonia transport" RELATED [] +is_a: GO:0015672 ! monovalent inorganic cation transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015697 +name: quaternary ammonium group transport +namespace: biological_process +alt_id: GO:0015845 +def: "The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups." [GOC:ai, ISBN:0198506732] +synonym: "quaternary amine transport" EXACT [] +synonym: "quaternary ammonium compound transport" EXACT [] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015698 +name: inorganic anion transport +namespace: biological_process +def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] +is_a: GO:0006820 ! anion transport + +[Term] +id: GO:0015699 +name: antimonite transport +namespace: biological_process +def: "The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015700 +name: arsenite transport +namespace: biological_process +def: "The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015701 +name: bicarbonate transport +namespace: biological_process +def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015711 ! organic anion transport + +[Term] +id: GO:0015702 +name: chlorate transport +namespace: biological_process +def: "The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015703 +name: chromate transport +namespace: biological_process +def: "The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015704 +name: cyanate transport +namespace: biological_process +def: "The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0006820 ! anion transport +is_a: GO:0019755 ! one-carbon compound transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015705 +name: iodide transport +namespace: biological_process +def: "The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015706 +name: nitrate transport +namespace: biological_process +alt_id: GO:0006872 +alt_id: GO:0080055 +def: "The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "low affinity nitrate transport" NARROW [] +synonym: "low-affinity nitrate transport" NARROW [] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015707 +name: nitrite transport +namespace: biological_process +def: "The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015708 +name: silicic acid import across plasma membrane +namespace: biological_process +alt_id: GO:0051207 +alt_id: GO:1902067 +def: "The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates." [GOC:ai, GOC:krc, PMID:16572174] +synonym: "silicate transport" BROAD [] +synonym: "silicic acid import" RELATED [] +synonym: "silicic acid transport" EXACT [] +synonym: "silicon uptake" RELATED [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098661 ! inorganic anion transmembrane transport +is_a: GO:0098739 ! import across plasma membrane +created_by: tb +creation_date: 2013-04-17T20:53:16Z + +[Term] +id: GO:0015709 +name: thiosulfate transport +namespace: biological_process +def: "The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "thiosulphate transport" EXACT [] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015710 +name: tellurite transport +namespace: biological_process +def: "The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0015711 +name: organic anion transport +namespace: biological_process +def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] +is_a: GO:0006820 ! anion transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015712 +name: hexose phosphate transport +namespace: biological_process +def: "The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015713 +name: phosphoglycerate transmembrane transport +namespace: biological_process +def: "The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "phosphoglycerate transport" RELATED [] +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0042873 ! aldonate transmembrane transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015714 +name: phosphoenolpyruvate transport +namespace: biological_process +def: "The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015748 ! organophosphate ester transport + +[Term] +id: GO:0015715 +name: nucleotide-sulfate transport +namespace: biological_process +def: "The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "nucleotide-sulphate transport" EXACT [] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015716 +name: organic phosphonate transport +namespace: biological_process +def: "The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)." [GOC:krc] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015717 +name: triose phosphate transport +namespace: biological_process +def: "The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "aldotriose phosphate transport" EXACT [] +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015718 +name: monocarboxylic acid transport +namespace: biological_process +def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0046942 ! carboxylic acid transport + +[Term] +id: GO:0015719 +name: allantoate transport +namespace: biological_process +def: "The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "allantoin/allantoate transport" BROAD [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0015720 +name: allantoin transport +namespace: biological_process +def: "The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "allantoin transmembrane transport" EXACT [GOC:mah] +synonym: "allantoin/allantoate transport" BROAD [] +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015721 +name: bile acid and bile salt transport +namespace: biological_process +def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] +synonym: "bile acid transport" NARROW [] +synonym: "bile salt transport" NARROW [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015722 +name: canalicular bile acid transport +namespace: biological_process +def: "Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:dph] +is_a: GO:0015721 ! bile acid and bile salt transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0015723 +name: bilirubin transport +namespace: biological_process +def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015724 +name: formate transport +namespace: biological_process +def: "The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0015726 +name: L-idonate transmembrane transport +namespace: biological_process +def: "The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:krc] +synonym: "L-idonate transport" RELATED [] +is_a: GO:0042873 ! aldonate transmembrane transport + +[Term] +id: GO:0015727 +name: lactate transport +namespace: biological_process +def: "The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:ai, ISBN:0198506732] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015728 +name: mevalonate transport +namespace: biological_process +def: "The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015729 +name: oxaloacetate transport +namespace: biological_process +def: "The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015740 ! C4-dicarboxylate transport + +[Term] +id: GO:0015730 +name: propanoate transport +namespace: biological_process +def: "The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "propionate transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0015912 ! short-chain fatty acid transport + +[Term] +id: GO:0015731 +name: 3-hydroxyphenyl propanoate transport +namespace: biological_process +def: "The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "3-hydroxyphenyl propionate transport" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015732 +name: prostaglandin transport +namespace: biological_process +def: "The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015908 ! fatty acid transport +is_a: GO:0071715 ! icosanoid transport + +[Term] +id: GO:0015733 +name: shikimate transmembrane transport +namespace: biological_process +def: "The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "shikimate transport" RELATED [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0015734 +name: taurine transport +namespace: biological_process +def: "The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0042918 ! alkanesulfonate transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015735 +name: uronic acid transmembrane transport +namespace: biological_process +def: "The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "uronic acid transport" RELATED [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015749 ! monosaccharide transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0015736 +name: hexuronate transmembrane transport +namespace: biological_process +def: "The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6." [GOC:ai, ISBN:0198506732] +synonym: "hexuronate transport" RELATED [] +is_a: GO:0015735 ! uronic acid transmembrane transport + +[Term] +id: GO:0015737 +name: galacturonate transmembrane transport +namespace: biological_process +def: "The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "galacturonate transport" RELATED [] +is_a: GO:0015736 ! hexuronate transmembrane transport + +[Term] +id: GO:0015738 +name: glucuronate transmembrane transport +namespace: biological_process +def: "The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "glucuronate transport" RELATED [] +is_a: GO:0015736 ! hexuronate transmembrane transport + +[Term] +id: GO:0015739 +name: sialic acid transport +namespace: biological_process +def: "The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015740 +name: C4-dicarboxylate transport +namespace: biological_process +def: "The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms." [GOC:krc, GOC:mah] +is_a: GO:0006835 ! dicarboxylic acid transport + +[Term] +id: GO:0015741 +name: fumarate transport +namespace: biological_process +def: "The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015740 ! C4-dicarboxylate transport + +[Term] +id: GO:0015742 +name: alpha-ketoglutarate transport +namespace: biological_process +def: "The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "2-oxoglutarate transport" EXACT [] +synonym: "mitochondrial alpha-ketoglutarate/malate transport" RELATED [] +is_a: GO:0006835 ! dicarboxylic acid transport + +[Term] +id: GO:0015743 +name: malate transport +namespace: biological_process +def: "The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "mitochondrial alpha-ketoglutarate/malate transport" RELATED [] +is_a: GO:0015740 ! C4-dicarboxylate transport + +[Term] +id: GO:0015744 +name: succinate transport +namespace: biological_process +def: "The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0015745 +name: tartrate transmembrane transport +namespace: biological_process +def: "The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] +synonym: "tartrate transport" RELATED [] +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0042869 ! aldarate transmembrane transport + +[Term] +id: GO:0015746 +name: citrate transport +namespace: biological_process +def: "The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0006842 ! tricarboxylic acid transport + +[Term] +id: GO:0015747 +name: urate transport +namespace: biological_process +def: "The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +synonym: "urate transmembrane transport" EXACT [GOC:mah] +synonym: "uric acid transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015748 +name: organophosphate ester transport +namespace: biological_process +def: "The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds." [GOC:mcc] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015749 +name: monosaccharide transmembrane transport +namespace: biological_process +alt_id: GO:1905950 +def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] +synonym: "monosaccharide transport" RELATED [] +is_a: GO:0034219 ! carbohydrate transmembrane transport +created_by: vw +creation_date: 2017-02-19T10:41:27Z + +[Term] +id: GO:0015750 +name: pentose transmembrane transport +namespace: biological_process +def: "The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule." [GOC:ai] +synonym: "pentose transport" RELATED [] +is_a: GO:0015749 ! monosaccharide transmembrane transport + +[Term] +id: GO:0015751 +name: arabinose transmembrane transport +namespace: biological_process +def: "The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl] +synonym: "arabinose transport" RELATED [] +is_a: GO:0015750 ! pentose transmembrane transport + +[Term] +id: GO:0015752 +name: D-ribose transmembrane transport +namespace: biological_process +def: "The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12." [GOC:ai] +synonym: "D-ribose transport" RELATED [] +is_a: GO:0015750 ! pentose transmembrane transport + +[Term] +id: GO:0015753 +name: D-xylose transmembrane transport +namespace: biological_process +def: "The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides." [GOC:ai] +synonym: "D-xylose transport" RELATED [] +is_a: GO:0015750 ! pentose transmembrane transport + +[Term] +id: GO:0015754 +name: allose transmembrane transport +namespace: biological_process +def: "The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [GOC:ai] +synonym: "allose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015755 +name: fructose transmembrane transport +namespace: biological_process +def: "The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey." [GOC:ai] +synonym: "fructose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015756 +name: fucose transmembrane transport +namespace: biological_process +def: "The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose." [GOC:ai] +synonym: "fucose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015757 +name: galactose transmembrane transport +namespace: biological_process +def: "The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [GOC:ai] +synonym: "galactose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015759 +name: beta-glucoside transport +namespace: biological_process +def: "The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration." [GOC:jl, http://www.biochem.purdue.edu/, ISBN:0198506732] +is_a: GO:0042946 ! glucoside transport + +[Term] +id: GO:0015760 +name: glucose-6-phosphate transport +namespace: biological_process +def: "The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015712 ! hexose phosphate transport + +[Term] +id: GO:0015761 +name: mannose transmembrane transport +namespace: biological_process +def: "The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins." [GOC:ai] +synonym: "mannose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015762 +name: rhamnose transmembrane transport +namespace: biological_process +def: "The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [GOC:ai] +synonym: "rhamnose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport + +[Term] +id: GO:0015763 +name: N-acetylgalactosamine transport +namespace: biological_process +def: "The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine." [GOC:ai] +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015764 +name: N-acetylglucosamine transport +namespace: biological_process +def: "The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015765 +name: methylgalactoside transport +namespace: biological_process +def: "The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group." [GOC:curators] +is_a: GO:1901656 ! glycoside transport + +[Term] +id: GO:0015766 +name: disaccharide transport +namespace: biological_process +def: "The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units." [GOC:ai] +is_a: GO:0015772 ! oligosaccharide transport + +[Term] +id: GO:0015767 +name: lactose transport +namespace: biological_process +def: "The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015768 +name: maltose transport +namespace: biological_process +def: "The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015769 +name: melibiose transport +namespace: biological_process +def: "The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015770 +name: sucrose transport +namespace: biological_process +def: "The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015771 +name: trehalose transport +namespace: biological_process +def: "The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0015772 +name: oligosaccharide transport +namespace: biological_process +def: "The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport + +[Term] +id: GO:0015773 +name: raffinose transport +namespace: biological_process +def: "The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol." [ISBN:0198506732] +is_a: GO:2001088 ! trisaccharide transport + +[Term] +id: GO:0015774 +name: polysaccharide transport +namespace: biological_process +def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +relationship: part_of GO:0033037 ! polysaccharide localization + +[Term] +id: GO:0015775 +name: beta-glucan transport +namespace: biological_process +def: "The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds." [GOC:ai] +is_a: GO:0015774 ! polysaccharide transport + +[Term] +id: GO:0015776 +name: capsular polysaccharide transport +namespace: biological_process +def: "The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi." [GOC:ai] +synonym: "capsular-polysaccharide transport" EXACT [] +synonym: "capsule polysaccharide transport" EXACT [] +is_a: GO:0015774 ! polysaccharide transport + +[Term] +id: GO:0015777 +name: teichoic acid transport +namespace: biological_process +def: "The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues." [GOC:ai] +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015778 +name: hexuronide transport +namespace: biological_process +def: "The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport + +[Term] +id: GO:0015779 +name: glucuronoside transport +namespace: biological_process +def: "The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate." [GOC:ai] +synonym: "glucuronide transport" EXACT [] +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:1901656 ! glycoside transport + +[Term] +id: GO:0015780 +name: nucleotide-sugar transmembrane transport +namespace: biological_process +def: "The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [ISBN:0198506732] +synonym: "nucleotide-sugar transport" RELATED [] +is_a: GO:0015931 ! nucleobase-containing compound transport +is_a: GO:0055085 ! transmembrane transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015782 +name: CMP-N-acetylneuraminate transmembrane transport +namespace: biological_process +def: "The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "CMP-N-acetylneuraminate transport" RELATED [] +synonym: "CMP-sialic acid transport" BROAD [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0015783 +name: GDP-fucose transmembrane transport +namespace: biological_process +def: "The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-fucose transport" RELATED [] +is_a: GO:0090480 ! purine nucleotide-sugar transmembrane transport + +[Term] +id: GO:0015786 +name: UDP-glucose transmembrane transport +namespace: biological_process +def: "The process in which UDP-glucose is transported across a membrane." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0015787 +name: UDP-glucuronic acid transmembrane transport +namespace: biological_process +def: "The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-glucuronic acid transport" RELATED [] +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0015789 +name: UDP-N-acetylgalactosamine transmembrane transport +namespace: biological_process +def: "The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylgalactosamine transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0015790 +name: UDP-xylose transmembrane transport +namespace: biological_process +def: "The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-xylose transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0015791 +name: polyol transport +namespace: biological_process +def: "The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015792 +name: arabinitol transmembrane transport +namespace: biological_process +def: "The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms." [ISBN:0198506732] +synonym: "arabinitol transport" RELATED [] +synonym: "arabitol transport" RELATED [GOC:dph, GOC:tb] +is_a: GO:0015791 ! polyol transport +is_a: GO:0034219 ! carbohydrate transmembrane transport + +[Term] +id: GO:0015793 +name: glycerol transport +namespace: biological_process +def: "The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015794 +name: glycerol-3-phosphate transmembrane transport +namespace: biological_process +def: "The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol." [GOC:ai] +synonym: "glycerol-3-phosphate transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015795 +name: sorbitol transport +namespace: biological_process +def: "The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose." [GOC:ai, ISBN:0198506732] +synonym: "glucitol transport" EXACT [] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015796 +name: galactitol transport +namespace: biological_process +def: "The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015797 +name: mannitol transport +namespace: biological_process +def: "The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015798 +name: myo-inositol transport +namespace: biological_process +def: "The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms." [GOC:ai] +synonym: "vitamin Bh transport" EXACT [] +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015799 +name: propanediol transport +namespace: biological_process +def: "The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects." [http://www.rhymezone.com] +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0015800 +name: acidic amino acid transport +namespace: biological_process +def: "The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015801 +name: aromatic amino acid transport +namespace: biological_process +def: "The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015802 +name: basic amino acid transport +namespace: biological_process +def: "The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015803 +name: branched-chain amino acid transport +namespace: biological_process +alt_id: GO:1900755 +def: "The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings." [GOC:ai, GOC:bf] +synonym: "branched-chain aliphatic amino acid transport" EXACT [] +synonym: "branched-chain amino-acid anion transport" EXACT [GOC:jl] +synonym: "branched-chain amino-acid anions transport" RELATED [GOC:TermGenie] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015804 +name: neutral amino acid transport +namespace: biological_process +def: "The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015805 +name: S-adenosyl-L-methionine transport +namespace: biological_process +def: "The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "S-adenosyl methionine transport" EXACT [] +synonym: "S-adenosylmethionine transport" EXACT [] +synonym: "SAM transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015806 +name: S-methylmethionine transport +namespace: biological_process +def: "The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015807 +name: L-amino acid transport +namespace: biological_process +def: "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, GOC:jsg, GOC:mah] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015808 +name: L-alanine transport +namespace: biological_process +def: "The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, GOC:jsg, GOC:mah] +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0032328 ! alanine transport + +[Term] +id: GO:0015809 +name: arginine transport +namespace: biological_process +def: "The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +synonym: "L-arginine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015802 ! basic amino acid transport + +[Term] +id: GO:0015810 +name: aspartate transmembrane transport +namespace: biological_process +def: "The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:go_curators, ISBN:0198506732] +synonym: "aspartate transport" BROAD [] +synonym: "mitochondrial aspartate/glutamate transport" RELATED [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0015800 ! acidic amino acid transport + +[Term] +id: GO:0015811 +name: L-cystine transport +namespace: biological_process +def: "The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0000101 ! sulfur amino acid transport +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0015812 +name: gamma-aminobutyric acid transport +namespace: biological_process +def: "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +comment: See also the biological process term 'neurotransmitter transport ; GO:0006836'. +synonym: "4-aminobutanoate transport" EXACT [] +synonym: "4-aminobutyrate transport" EXACT [] +synonym: "GABA transport" EXACT [] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0006865 ! amino acid transport +is_a: GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0015813 +name: L-glutamate transmembrane transport +namespace: biological_process +alt_id: GO:0089711 +def: "The directed movement of L-glutamate across a membrane." [PMID:21307582] +synonym: "L-glutamate transport" BROAD [] +synonym: "mitochondrial aspartate/glutamate transport" RELATED [] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport + +[Term] +id: GO:0015814 +name: p-aminobenzoyl-glutamate transport +namespace: biological_process +def: "The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0042938 ! dipeptide transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0015816 +name: glycine transport +namespace: biological_process +def: "The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006812 ! cation transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0015817 +name: histidine transport +namespace: biological_process +def: "The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-histidine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015801 ! aromatic amino acid transport +is_a: GO:0015802 ! basic amino acid transport + +[Term] +id: GO:0015818 +name: isoleucine transport +namespace: biological_process +def: "The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-isoleucine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015803 ! branched-chain amino acid transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015819 +name: lysine transport +namespace: biological_process +alt_id: GO:0034226 +alt_id: GO:0061461 +def: "The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-lysine import" NARROW [] +synonym: "L-lysine transport" NARROW [] +synonym: "lysine import" NARROW [] +synonym: "lysine uptake" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015802 ! basic amino acid transport +created_by: dph +creation_date: 2012-10-05T10:22:26Z + +[Term] +id: GO:0015820 +name: leucine transport +namespace: biological_process +def: "The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-leucine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015803 ! branched-chain amino acid transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015821 +name: methionine transport +namespace: biological_process +def: "The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-methionine transport" NARROW [] +is_a: GO:0000101 ! sulfur amino acid transport +is_a: GO:0006812 ! cation transport + +[Term] +id: GO:0015822 +name: ornithine transport +namespace: biological_process +def: "The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-ornithine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015823 +name: phenylalanine transport +namespace: biological_process +def: "The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-phenylalanine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015801 ! aromatic amino acid transport + +[Term] +id: GO:0015824 +name: proline transport +namespace: biological_process +def: "The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-proline transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015825 +name: L-serine transport +namespace: biological_process +alt_id: GO:0090479 +def: "The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-serine import" NARROW [] +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0032329 ! serine transport +created_by: tb +creation_date: 2012-10-01T11:10:51Z + +[Term] +id: GO:0015826 +name: threonine transport +namespace: biological_process +def: "The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-threonine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015827 +name: tryptophan transport +namespace: biological_process +def: "The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-tryptophan transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015801 ! aromatic amino acid transport + +[Term] +id: GO:0015828 +name: tyrosine transport +namespace: biological_process +def: "The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-tyrosine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015801 ! aromatic amino acid transport + +[Term] +id: GO:0015829 +name: valine transport +namespace: biological_process +def: "The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "L-valine transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015803 ! branched-chain amino acid transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0015830 +name: diaminopimelate transport +namespace: biological_process +def: "The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0015832 +name: obsolete holin +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "holin" EXACT [] +is_obsolete: true +consider: GO:0019835 + +[Term] +id: GO:0015833 +name: peptide transport +namespace: biological_process +def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +is_a: GO:0042886 ! amide transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015834 +name: peptidoglycan-associated peptide transport +namespace: biological_process +def: "The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains." [ISBN:0198506732] +synonym: "murein peptide transport" EXACT [] +synonym: "muropeptide transport" EXACT [] +synonym: "peptidoglycan peptide transport" EXACT [GOC:mah] +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0015835 +name: peptidoglycan transport +namespace: biological_process +def: "The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +synonym: "murein transport" EXACT [] +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015836 +name: lipid-linked peptidoglycan transport +namespace: biological_process +def: "The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "lipid-linked murein transport" EXACT [] +is_a: GO:0015835 ! peptidoglycan transport + +[Term] +id: GO:0015837 +name: amine transport +namespace: biological_process +def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] +subset: goslim_pir +synonym: "amine/polyamine transport" RELATED [] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015838 +name: amino-acid betaine transport +namespace: biological_process +def: "The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "betaine transport" EXACT [] +is_a: GO:0015697 ! quaternary ammonium group transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0015839 +name: cadaverine transport +namespace: biological_process +def: "The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015840 +name: urea transport +namespace: biological_process +def: "The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2." [GOC:ai, ISBN:0198506732] +is_a: GO:0019755 ! one-carbon compound transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0015841 +name: chromaffin granule amine transport +namespace: biological_process +def: "The directed movement of amines into, out of or within chromaffin granules." [GOC:mah] +is_a: GO:0015837 ! amine transport + +[Term] +id: GO:0015842 +name: aminergic neurotransmitter loading into synaptic vesicle +namespace: biological_process +def: "The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps." [GOC:ai] +is_a: GO:0015837 ! amine transport +is_a: GO:0098700 ! neurotransmitter loading into synaptic vesicle + +[Term] +id: GO:0015843 +name: methylammonium transport +namespace: biological_process +def: "The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015837 ! amine transport +is_a: GO:0019755 ! one-carbon compound transport + +[Term] +id: GO:0015844 +name: monoamine transport +namespace: biological_process +alt_id: GO:0015873 +def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015846 +name: polyamine transport +namespace: biological_process +def: "The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc, ISBN:0198506732] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015847 +name: putrescine transport +namespace: biological_process +def: "The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine." [GOC:krc, ISBN:0198506732] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015846 ! polyamine transport + +[Term] +id: GO:0015848 +name: spermidine transport +namespace: biological_process +def: "The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc, ISBN:0198506732] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015846 ! polyamine transport + +[Term] +id: GO:0015849 +name: organic acid transport +namespace: biological_process +def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] +subset: goslim_pir +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015850 +name: organic hydroxy compound transport +namespace: biological_process +def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai] +synonym: "organic alcohol transport" EXACT [] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015851 +name: nucleobase transport +namespace: biological_process +def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] +synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015853 +name: adenine transport +namespace: biological_process +def: "The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +synonym: "adenine transmembrane transport" EXACT [GOC:mah] +is_a: GO:0006863 ! purine nucleobase transport + +[Term] +id: GO:0015854 +name: guanine transport +namespace: biological_process +def: "The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0006863 ! purine nucleobase transport + +[Term] +id: GO:0015855 +name: pyrimidine nucleobase transport +namespace: biological_process +def: "The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "pyrimidine base transmembrane transport" EXACT [GOC:mah] +synonym: "pyrimidine base transport" EXACT [GOC:go_curators] +synonym: "pyrimidine transmembrane transport" RELATED [GOC:mah] +synonym: "pyrimidine transport" RELATED [] +is_a: GO:0015851 ! nucleobase transport + +[Term] +id: GO:0015856 +name: cytosine transport +namespace: biological_process +def: "The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +synonym: "cytosine transmembrane transport" EXACT [GOC:mah] +is_a: GO:0015855 ! pyrimidine nucleobase transport + +[Term] +id: GO:0015857 +name: uracil transport +namespace: biological_process +def: "The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015855 ! pyrimidine nucleobase transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0015858 +name: nucleoside transport +namespace: biological_process +def: "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015931 ! nucleobase-containing compound transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015859 +name: intracellular nucleoside transport +namespace: biological_process +def: "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell." [GOC:ai] +is_a: GO:0015858 ! nucleoside transport +is_a: GO:0046907 ! intracellular transport +intersection_of: GO:0015858 ! nucleoside transport +intersection_of: occurs_in GO:0005622 ! intracellular + +[Term] +id: GO:0015860 +name: purine nucleoside transmembrane transport +namespace: biological_process +alt_id: GO:0035427 +def: "The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar." [GOC:ai, GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "purine nucleoside membrane transport" EXACT [] +synonym: "purine nucleoside transport" BROAD [GOC:vw] +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:1901642 ! nucleoside transmembrane transport + +[Term] +id: GO:0015861 +name: cytidine transport +namespace: biological_process +def: "The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015864 ! pyrimidine nucleoside transport + +[Term] +id: GO:0015862 +name: uridine transport +namespace: biological_process +def: "The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015864 ! pyrimidine nucleoside transport + +[Term] +id: GO:0015863 +name: xanthosine transport +namespace: biological_process +def: "The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] +is_a: GO:0015858 ! nucleoside transport + +[Term] +id: GO:0015864 +name: pyrimidine nucleoside transport +namespace: biological_process +def: "The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015858 ! nucleoside transport + +[Term] +id: GO:0015865 +name: purine nucleotide transport +namespace: biological_process +def: "The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell." [GOC:ai] +is_a: GO:0006862 ! nucleotide transport + +[Term] +id: GO:0015866 +name: ADP transport +namespace: biological_process +def: "The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport + +[Term] +id: GO:0015867 +name: ATP transport +namespace: biological_process +def: "The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051503 ! adenine nucleotide transport + +[Term] +id: GO:0015868 +name: purine ribonucleotide transport +namespace: biological_process +def: "The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell." [GOC:ai] +is_a: GO:0015865 ! purine nucleotide transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015869 +name: protein-DNA complex transport +namespace: biological_process +def: "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "DNA-protein complex transport" EXACT [GOC:mah] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0051027 ! DNA transport + +[Term] +id: GO:0015870 +name: acetylcholine transport +namespace: biological_process +def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015893 ! drug transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901374 ! acetate ester transport + +[Term] +id: GO:0015871 +name: choline transport +namespace: biological_process +def: "The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:ai] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015695 ! organic cation transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015872 +name: dopamine transport +namespace: biological_process +def: "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:ai] +is_a: GO:0006812 ! cation transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051937 ! catecholamine transport + +[Term] +id: GO:0015874 +name: norepinephrine transport +namespace: biological_process +def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] +synonym: "levarterenol transport" EXACT [] +synonym: "noradrenaline transport" EXACT [] +is_a: GO:0051937 ! catecholamine transport + +[Term] +id: GO:0015875 +name: obsolete vitamin or cofactor transport +namespace: biological_process +def: "OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "vitamin or cofactor transport" EXACT [] +is_obsolete: true +consider: GO:0051180 +consider: GO:0051181 + +[Term] +id: GO:0015876 +name: acetyl-CoA transport +namespace: biological_process +def: "The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GOC:ai] +is_a: GO:0015916 ! fatty-acyl-CoA transport +is_a: GO:0051182 ! coenzyme transport + +[Term] +id: GO:0015877 +name: biopterin transport +namespace: biological_process +def: "The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme." [GOC:ai] +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015878 +name: biotin transport +namespace: biological_process +def: "The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:ai] +synonym: "vitamin B7 transport" EXACT [] +synonym: "vitamin H transport" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015879 +name: carnitine transport +namespace: biological_process +def: "The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:ai] +synonym: "vitamin Bt transport" EXACT [] +is_a: GO:0015838 ! amino-acid betaine transport + +[Term] +id: GO:0015880 +name: coenzyme A transport +namespace: biological_process +def: "The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0051503 ! adenine nucleotide transport + +[Term] +id: GO:0015881 +name: creatine transmembrane transport +namespace: biological_process +alt_id: GO:1902598 +def: "The directed movement of creatine across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "creatine transport" BROAD [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:01:18Z + +[Term] +id: GO:0015882 +name: L-ascorbic acid transmembrane transport +namespace: biological_process +def: "The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species." [GOC:ai] +synonym: "L-ascorbate transport" EXACT [] +synonym: "L-ascorbic acid transport" RELATED [] +synonym: "vitamin C transport" EXACT [] +is_a: GO:0015749 ! monosaccharide transmembrane transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0015883 +name: FAD transport +namespace: biological_process +def: "The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form." [ISBN:0198506732] +synonym: "flavin adenine dinucleotide transport" EXACT [] +synonym: "flavin-adenine dinucleotide transport" EXACT [] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0051182 ! coenzyme transport + +[Term] +id: GO:0015884 +name: folic acid transport +namespace: biological_process +def: "The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:ai] +synonym: "folate transport" EXACT [] +synonym: "vitamin B9 transport" EXACT [] +synonym: "vitamin M transport" EXACT [] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0015885 +name: 5-formyltetrahydrofolate transport +namespace: biological_process +def: "The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0015886 +name: heme transport +namespace: biological_process +def: "The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "haem transport" EXACT [] +is_a: GO:0051181 ! cofactor transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901678 ! iron coordination entity transport + +[Term] +id: GO:0015887 +name: pantothenate transmembrane transport +namespace: biological_process +def: "The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "pantothenate membrane transport" EXACT [] +synonym: "pantothenate transport" EXACT [GOC:mah] +synonym: "vitamin B5 transport" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0015888 +name: thiamine transport +namespace: biological_process +def: "The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:ai] +synonym: "thiamin transport" EXACT [] +synonym: "vitamin B1 transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0015889 +name: cobalamin transport +namespace: biological_process +def: "The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "vitamin B12 transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015890 +name: nicotinamide mononucleotide transport +namespace: biological_process +def: "The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP." [ISBN:0721662544] +synonym: "nicotinamide ribonucleotide transport" EXACT [] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015891 +name: siderophore transport +namespace: biological_process +alt_id: GO:0015892 +def: "The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +synonym: "iron-siderochrome transport" NARROW [] +synonym: "iron-siderophore transport" EXACT [] +synonym: "siderochrome transport" NARROW [] +synonym: "siderophore-iron transport" EXACT [] +is_a: GO:1901678 ! iron coordination entity transport + +[Term] +id: GO:0015893 +name: drug transport +namespace: biological_process +def: "The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +is_a: GO:0006810 ! transport +relationship: part_of GO:0042493 ! response to drug + +[Term] +id: GO:0015894 +name: acriflavine transport +namespace: biological_process +def: "The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication." [GOC:curators, PubChem_Compound:6842] +synonym: "acriflavin transport" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006821 ! chloride transport +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042908 ! xenobiotic transport + +[Term] +id: GO:0015895 +name: alkane transport +namespace: biological_process +def: "The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds." [GOC:ai] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015896 +name: nalidixic acid transport +namespace: biological_process +def: "The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication." [GOC:curators, PMID:12702699, PubChem_Compound:4221] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015897 +name: organomercurial transport +namespace: biological_process +def: "The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom." [GOC:ai, PMID:18793329] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015898 +name: amiloride transport +namespace: biological_process +def: "The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic." [GOC:ai] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015893 ! drug transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015899 +name: aminotriazole transport +namespace: biological_process +def: "The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity." [GOC:curators] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015900 +name: benomyl transport +namespace: biological_process +def: "The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit." [GOC:curators] +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0015901 +name: cycloheximide transport +namespace: biological_process +def: "The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes." [ISBN:0198506732] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0015902 +name: carbonyl cyanide m-chlorophenylhydrazone transport +namespace: biological_process +def: "The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes." [GOC:curators] +synonym: "CCCP transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015903 +name: fluconazole transport +namespace: biological_process +def: "The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections." [GOC:curators] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015904 +name: tetracycline transmembrane transport +namespace: biological_process +def: "The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [GOC:curators] +synonym: "tetracyclin transport" BROAD [] +synonym: "tetracycline transport" BROAD [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0015905 +name: bicyclomycin transmembrane transport +namespace: biological_process +def: "The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive." [PMID:20067529] +synonym: "bicyclomycin transport" BROAD [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015908 +name: fatty acid transport +namespace: biological_process +def: "The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [GOC:ai] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0015909 +name: long-chain fatty acid transport +namespace: biological_process +def: "The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:ai] +is_a: GO:0015908 ! fatty acid transport + +[Term] +id: GO:0015910 +name: long-chain fatty acid import into peroxisome +namespace: biological_process +def: "The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:ai] +synonym: "peroxisomal long-chain fatty acid import" EXACT [] +synonym: "peroxisomal long-chain fatty acid uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015909 ! long-chain fatty acid transport +is_a: GO:0015919 ! peroxisomal membrane transport +is_a: GO:0032365 ! intracellular lipid transport +is_a: GO:1902001 ! fatty acid transmembrane transport + +[Term] +id: GO:0015911 +name: long-chain fatty acid import across plasma membrane +namespace: biological_process +def: "The directed movement of long-chain fatty acids from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:ai] +synonym: "plasma membrane long-chain fatty acid transport" EXACT [] +is_a: GO:0044539 ! long-chain fatty acid import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1902001 ! fatty acid transmembrane transport + +[Term] +id: GO:0015912 +name: short-chain fatty acid transport +namespace: biological_process +def: "The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:ai] +is_a: GO:0015908 ! fatty acid transport + +[Term] +id: GO:0015913 +name: short-chain fatty acid import +namespace: biological_process +def: "The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6." [GOC:ai] +synonym: "short-chain fatty acid uptake" EXACT [] +is_a: GO:0015912 ! short-chain fatty acid transport + +[Term] +id: GO:0015914 +name: phospholipid transport +namespace: biological_process +def: "The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester." [GOC:ai] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport + +[Term] +id: GO:0015915 +name: fatty-acyl group transport +namespace: biological_process +def: "The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid." [GOC:ai] +synonym: "fatty acyl transport" EXACT [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0015916 +name: fatty-acyl-CoA transport +namespace: biological_process +def: "The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A)." [GOC:ai, ISBN:0198506732] +synonym: "fatty acyl CoA transport" EXACT [] +synonym: "fatty acyl coenzyme A transport" EXACT [] +synonym: "fatty acyl-CoA transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:1901337 ! thioester transport + +[Term] +id: GO:0015917 +name: aminophospholipid transport +namespace: biological_process +def: "The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group." [GOC:ai] +is_a: GO:0015914 ! phospholipid transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015918 +name: sterol transport +namespace: biological_process +def: "The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:ai] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0015919 +name: peroxisomal membrane transport +namespace: biological_process +def: "The directed movement of substances to, from or across the peroxisomal membrane." [GOC:ai] +is_a: GO:0043574 ! peroxisomal transport + +[Term] +id: GO:0015920 +name: lipopolysaccharide transport +namespace: biological_process +def: "The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [GOC:ai] +subset: goslim_pir +synonym: "LPS transport" EXACT [] +is_a: GO:0006869 ! lipid transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0015921 +name: lipopolysaccharide export +namespace: biological_process +def: "The directed movement of lipopolysaccharides out of a cell or organelle." [GOC:ai] +synonym: "LPS export" EXACT [] +is_a: GO:0015920 ! lipopolysaccharide transport + +[Term] +id: GO:0015922 +name: aspartate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide." [EC:1.4.3.1, EC:1.4.3.16] +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0015923 +name: mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative." [GOC:ai] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015924 +name: mannosyl-oligosaccharide mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides." [EC:3.2.1.-, GOC:ai] +xref: EC:3.2.1 +is_a: GO:0004559 ! alpha-mannosidase activity + +[Term] +id: GO:0015925 +name: galactosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative." [GOC:ai] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015926 +name: glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative." [ISBN:0198506732] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015927 +name: trehalase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of trehalose or a trehalose derivative." [GOC:ai] +xref: MetaCyc:TREHALA-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015928 +name: fucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative." [GOC:ai] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015929 +name: hexosaminidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides." [ISBN:0721662544] +xref: MetaCyc:3.2.1.52-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0015930 +name: glutamate synthase activity +namespace: molecular_function +def: "Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors." [EC:1.4.-.-] +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0015931 +name: nucleobase-containing compound transport +namespace: biological_process +def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +subset: goslim_yeast +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0015932 +name: nucleobase-containing compound transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0015933 +name: obsolete flavin-containing electron transporter +namespace: molecular_function +def: "OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins." [GOC:kd] +comment: This term was made obsolete because it does not describe a molecular function. +synonym: "flavin-containing electron transporter" EXACT [] +is_obsolete: true +replaced_by: GO:0009055 + +[Term] +id: GO:0015934 +name: large ribosomal subunit +namespace: cellular_component +def: "The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site)." [ISBN:0198506732] +synonym: "ribosomal large subunit" EXACT [] +is_a: GO:0044391 ! ribosomal subunit + +[Term] +id: GO:0015935 +name: small ribosomal subunit +namespace: cellular_component +def: "The smaller of the two subunits of a ribosome." [GOC:mah] +subset: goslim_pir +synonym: "ribosomal small subunit" EXACT [] +is_a: GO:0044391 ! ribosomal subunit + +[Term] +id: GO:0015936 +name: coenzyme A metabolic process +namespace: biological_process +alt_id: GO:0006763 +def: "The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [ISBN:0198547684] +synonym: "CoA metabolism" EXACT [] +synonym: "coenzyme A metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0033875 ! ribonucleoside bisphosphate metabolic process +is_a: GO:0034032 ! purine nucleoside bisphosphate metabolic process + +[Term] +id: GO:0015937 +name: coenzyme A biosynthetic process +namespace: biological_process +alt_id: GO:0006764 +def: "The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [ISBN:0198547684] +synonym: "CoA biosynthesis" EXACT [] +synonym: "coenzyme A anabolism" EXACT [] +synonym: "coenzyme A biosynthesis" EXACT [] +synonym: "coenzyme A formation" EXACT [] +synonym: "coenzyme A synthesis" EXACT [] +xref: MetaCyc:COA-PWY +xref: MetaCyc:PANTOSYN-PWY +xref: MetaCyc:PWY-4221 +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0015936 ! coenzyme A metabolic process +is_a: GO:0034030 ! ribonucleoside bisphosphate biosynthetic process +is_a: GO:0034033 ! purine nucleoside bisphosphate biosynthetic process + +[Term] +id: GO:0015938 +name: coenzyme A catabolic process +namespace: biological_process +alt_id: GO:0006765 +def: "The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [ISBN:0198547684] +synonym: "CoA catabolism" EXACT [] +synonym: "coenzyme A breakdown" EXACT [] +synonym: "coenzyme A catabolism" EXACT [] +synonym: "coenzyme A degradation" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0015936 ! coenzyme A metabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process + +[Term] +id: GO:0015939 +name: pantothenate metabolic process +namespace: biological_process +alt_id: GO:0006770 +def: "The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544] +synonym: "pantothenate metabolism" EXACT [] +synonym: "vitamin B5 metabolic process" EXACT [] +synonym: "vitamin B5 metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0015940 +name: pantothenate biosynthetic process +namespace: biological_process +alt_id: GO:0033317 +alt_id: GO:0033318 +def: "The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544] +synonym: "pantothenate anabolism" EXACT [] +synonym: "pantothenate anabolism from 2-oxypantoyl lactone" NARROW [] +synonym: "pantothenate anabolism from valine" NARROW [] +synonym: "pantothenate biosynthesis" EXACT [] +synonym: "pantothenate biosynthesis from 2-oxypantoyl lactone" NARROW [] +synonym: "pantothenate biosynthesis from valine" NARROW [] +synonym: "pantothenate biosynthetic process from 2-dehydropantolactone" NARROW [] +synonym: "pantothenate biosynthetic process from 2-oxypantoyl lactone" NARROW [] +synonym: "pantothenate biosynthetic process from valine" NARROW [] +synonym: "pantothenate formation" EXACT [] +synonym: "pantothenate formation from 2-oxypantoyl lactone" NARROW [] +synonym: "pantothenate formation from valine" NARROW [] +synonym: "pantothenate synthesis" EXACT [] +synonym: "pantothenate synthesis from 2-oxypantoyl lactone" NARROW [] +synonym: "pantothenate synthesis from valine" NARROW [] +synonym: "vitamin B5 biosynthesis" EXACT [] +synonym: "vitamin B5 biosynthetic process" EXACT [] +xref: MetaCyc:PANTO-PWY +xref: MetaCyc:PANTOSYN-PWY +xref: MetaCyc:PWY-3961 +xref: MetaCyc:PWY-4221 +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0015939 ! pantothenate metabolic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0015941 +name: pantothenate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544] +synonym: "pantothenate breakdown" EXACT [] +synonym: "pantothenate catabolism" EXACT [] +synonym: "pantothenate degradation" EXACT [] +synonym: "vitamin B5 catabolic process" EXACT [] +synonym: "vitamin B5 catabolism" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0015939 ! pantothenate metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0015942 +name: formate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] +synonym: "formate metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0015943 +name: formate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] +synonym: "formate anabolism" EXACT [] +synonym: "formate biosynthesis" EXACT [] +synonym: "formate formation" EXACT [] +synonym: "formate synthesis" EXACT [] +synonym: "formic acid biosynthesis" EXACT [] +synonym: "formic acid biosynthetic process" EXACT [] +is_a: GO:0015942 ! formate metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0015944 +name: formate oxidation +namespace: biological_process +def: "The chemical reactions and pathways by which formate is converted to CO2." [MetaCyc:PWY-1881] +synonym: "formic acid oxidation" EXACT [] +xref: MetaCyc:PWY-1881 +is_a: GO:0015942 ! formate metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0015945 +name: methanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent." [GOC:go_curators, ISBN:0198506732] +synonym: "methanol metabolism" EXACT [] +is_a: GO:0034308 ! primary alcohol metabolic process + +[Term] +id: GO:0015946 +name: methanol oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M." [MetaCyc:CO2FORM-PWY] +xref: MetaCyc:CO2FORM-PWY +is_a: GO:0015945 ! methanol metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0015947 +name: methane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes." [ISBN:0198506732] +synonym: "methane metabolism" EXACT [] +is_a: GO:0043446 ! cellular alkane metabolic process + +[Term] +id: GO:0015948 +name: methanogenesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes." [GOC:ai] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "methane biosynthesis" EXACT [] +synonym: "methane biosynthetic process" EXACT [] +xref: UM-BBD_pathwayID:meth +xref: Wikipedia:Methanogenesis +is_a: GO:0009061 ! anaerobic respiration +is_a: GO:0015947 ! methane metabolic process +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds +is_a: GO:0043447 ! alkane biosynthetic process + +[Term] +id: GO:0015949 +name: nucleobase-containing small molecule interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +subset: goslim_pir +xref: MetaCyc:P1-PWY +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process + +[Term] +id: GO:0015950 +name: purine nucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0006163 ! purine nucleotide metabolic process +is_a: GO:0015949 ! nucleobase-containing small molecule interconversion + +[Term] +id: GO:0015951 +name: purine ribonucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0015950 ! purine nucleotide interconversion + +[Term] +id: GO:0015952 +name: purine deoxyribonucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0015950 ! purine nucleotide interconversion + +[Term] +id: GO:0015953 +name: pyrimidine nucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0015949 ! nucleobase-containing small molecule interconversion + +[Term] +id: GO:0015954 +name: pyrimidine ribonucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process +is_a: GO:0015953 ! pyrimidine nucleotide interconversion + +[Term] +id: GO:0015955 +name: pyrimidine deoxyribonucleotide interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process +is_a: GO:0015953 ! pyrimidine nucleotide interconversion + +[Term] +id: GO:0015956 +name: bis(5'-nucleosidyl) oligophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules." [GOC:mah, PMID:10970777] +synonym: "bis(5'-nucleosidyl) oligophosphate metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0015957 +name: bis(5'-nucleosidyl) oligophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules." [GOC:mah, PMID:10970777] +synonym: "bis(5'-nucleosidyl) oligophosphate anabolism" EXACT [] +synonym: "bis(5'-nucleosidyl) oligophosphate biosynthesis" EXACT [] +synonym: "bis(5'-nucleosidyl) oligophosphate formation" EXACT [] +synonym: "bis(5'-nucleosidyl) oligophosphate synthesis" EXACT [] +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0015956 ! bis(5'-nucleosidyl) oligophosphate metabolic process + +[Term] +id: GO:0015958 +name: bis(5'-nucleosidyl) oligophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules." [GOC:mah, PMID:10970777] +synonym: "bis(5'-nucleosidyl) oligophosphate breakdown" EXACT [] +synonym: "bis(5'-nucleosidyl) oligophosphate catabolism" EXACT [] +synonym: "bis(5'-nucleosidyl) oligophosphate degradation" EXACT [] +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0015956 ! bis(5'-nucleosidyl) oligophosphate metabolic process + +[Term] +id: GO:0015959 +name: diadenosine polyphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached." [GOC:ai] +synonym: "diadenosine polyphosphate metabolism" EXACT [] +is_a: GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0015960 +name: diadenosine polyphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached." [GOC:ai] +synonym: "diadenosine polyphosphate anabolism" EXACT [] +synonym: "diadenosine polyphosphate biosynthesis" EXACT [] +synonym: "diadenosine polyphosphate formation" EXACT [] +synonym: "diadenosine polyphosphate synthesis" EXACT [] +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process + +[Term] +id: GO:0015961 +name: diadenosine polyphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached." [GOC:ai] +synonym: "diadenosine polyphosphate breakdown" EXACT [] +synonym: "diadenosine polyphosphate catabolism" EXACT [] +synonym: "diadenosine polyphosphate degradation" EXACT [] +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process + +[Term] +id: GO:0015962 +name: diadenosine triphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached." [GOC:ai] +synonym: "diadenosine triphosphate metabolism" EXACT [] +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process + +[Term] +id: GO:0015963 +name: diadenosine triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached." [GOC:ai] +synonym: "diadenosine triphosphate anabolism" EXACT [] +synonym: "diadenosine triphosphate biosynthesis" EXACT [] +synonym: "diadenosine triphosphate formation" EXACT [] +synonym: "diadenosine triphosphate synthesis" EXACT [] +is_a: GO:0015960 ! diadenosine polyphosphate biosynthetic process +is_a: GO:0015962 ! diadenosine triphosphate metabolic process + +[Term] +id: GO:0015964 +name: diadenosine triphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached." [GOC:ai] +synonym: "diadenosine triphosphate breakdown" EXACT [] +synonym: "diadenosine triphosphate catabolism" EXACT [] +synonym: "diadenosine triphosphate degradation" EXACT [] +is_a: GO:0015961 ! diadenosine polyphosphate catabolic process +is_a: GO:0015962 ! diadenosine triphosphate metabolic process + +[Term] +id: GO:0015965 +name: diadenosine tetraphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached." [GOC:ai] +synonym: "diadenosine tetraphosphate metabolism" EXACT [] +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process + +[Term] +id: GO:0015966 +name: diadenosine tetraphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached." [GOC:ai] +synonym: "diadenosine tetraphosphate anabolism" EXACT [] +synonym: "diadenosine tetraphosphate biosynthesis" EXACT [] +synonym: "diadenosine tetraphosphate formation" EXACT [] +synonym: "diadenosine tetraphosphate synthesis" EXACT [] +is_a: GO:0015960 ! diadenosine polyphosphate biosynthetic process +is_a: GO:0015965 ! diadenosine tetraphosphate metabolic process + +[Term] +id: GO:0015967 +name: diadenosine tetraphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached." [GOC:ai] +synonym: "diadenosine tetraphosphate breakdown" EXACT [] +synonym: "diadenosine tetraphosphate catabolism" EXACT [] +synonym: "diadenosine tetraphosphate degradation" EXACT [] +is_a: GO:0015961 ! diadenosine polyphosphate catabolic process +is_a: GO:0015965 ! diadenosine tetraphosphate metabolic process + +[Term] +id: GO:0015968 +name: stringent response +namespace: biological_process +def: "A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation." [GOC:jl, ISBN:0124325653, PMID:11282471] +xref: Wikipedia:Stringent_response +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0015969 +name: guanosine tetraphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates." [GOC:ai] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') metabolic process" EXACT [] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') metabolism" EXACT [] +synonym: "guanosine tetraphosphate metabolism" EXACT [] +xref: MetaCyc:PPGPPMET-PWY +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0034035 ! purine ribonucleoside bisphosphate metabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0015970 +name: guanosine tetraphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates." [GOC:ai] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') biosynthesis" EXACT [] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') biosynthetic process" EXACT [] +synonym: "guanosine tetraphosphate anabolism" EXACT [] +synonym: "guanosine tetraphosphate biosynthesis" EXACT [] +synonym: "guanosine tetraphosphate formation" EXACT [] +synonym: "guanosine tetraphosphate synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0015969 ! guanosine tetraphosphate metabolic process +is_a: GO:0034036 ! purine ribonucleoside bisphosphate biosynthetic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0015971 +name: guanosine tetraphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates." [GOC:ai] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') catabolic process" EXACT [] +synonym: "guanosine tetraphosphate (5'-ppGpp-3') catabolism" EXACT [] +synonym: "guanosine tetraphosphate breakdown" EXACT [] +synonym: "guanosine tetraphosphate catabolism" EXACT [] +synonym: "guanosine tetraphosphate degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0015969 ! guanosine tetraphosphate metabolic process +is_a: GO:0034037 ! purine ribonucleoside bisphosphate catabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0015972 +name: guanosine pentaphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates." [GOC:ai] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') metabolic process" EXACT [] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') metabolism" EXACT [] +synonym: "guanosine pentaphosphate metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0034035 ! purine ribonucleoside bisphosphate metabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0015973 +name: guanosine pentaphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates." [GOC:ai] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') biosynthesis" EXACT [] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') biosynthetic process" EXACT [] +synonym: "guanosine pentaphosphate anabolism" EXACT [] +synonym: "guanosine pentaphosphate biosynthesis" EXACT [] +synonym: "guanosine pentaphosphate formation" EXACT [] +synonym: "guanosine pentaphosphate synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0015972 ! guanosine pentaphosphate metabolic process +is_a: GO:0034036 ! purine ribonucleoside bisphosphate biosynthetic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0015974 +name: guanosine pentaphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates." [GOC:ai] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') catabolic process" EXACT [] +synonym: "guanosine pentaphosphate (5'-pppGpp-3') catabolism" EXACT [] +synonym: "guanosine pentaphosphate breakdown" EXACT [] +synonym: "guanosine pentaphosphate catabolism" EXACT [] +synonym: "guanosine pentaphosphate degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0015972 ! guanosine pentaphosphate metabolic process +is_a: GO:0034037 ! purine ribonucleoside bisphosphate catabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0015975 +name: energy derivation by oxidation of reduced inorganic compounds +namespace: biological_process +def: "The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] +synonym: "chemolithotrophie" EXACT [] +synonym: "chemolithotrophy" EXACT [] +synonym: "lithotrophy" EXACT [Wikipedia:Lithotrophy] +xref: Wikipedia:Lithotrophy +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0015976 +name: carbon utilization +namespace: biological_process +alt_id: GO:0015978 +def: "A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism." [GOC:mah, GOC:mlg] +subset: goslim_chembl +subset: goslim_pir +synonym: "carbon utilization by utilization of organic compounds" EXACT [GOC:mah] +synonym: "heterotrophy" EXACT [] +xref: Wikipedia:Heterotroph +is_a: GO:0008150 ! biological_process +relationship: has_part GO:0071702 ! organic substance transport +relationship: has_part GO:0071703 ! detection of organic substance +relationship: has_part GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0015977 +name: carbon fixation +namespace: biological_process +def: "A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates)." [GOC:jl, GOC:mah] +synonym: "autotrophic CO2 fixation" EXACT [] +synonym: "autotrophic CO2 fixation pathway" EXACT [] +synonym: "autotrophy" EXACT [] +synonym: "carbon dioxide fixation" NARROW [] +xref: Wikipedia:Carbon_fixation +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0015979 +name: photosynthesis +namespace: biological_process +def: "The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds." [ISBN:0198547684] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +xref: Wikipedia:Photosynthesis +is_a: GO:0044237 ! cellular metabolic process +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0015980 +name: energy derivation by oxidation of organic compounds +namespace: biological_process +def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] +synonym: "chemoorganotrophy" EXACT [] +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0015981 +name: obsolete passive proton transport, down the electrochemical gradient +namespace: biological_process +def: "OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low." [ISBN:0716731363] +comment: This term was made obsolete because it represents a passive process which occurs without the aid of gene products. +synonym: "passive proton transport, down the electrochemical gradient" EXACT [] +is_obsolete: true +consider: GO:1902600 + +[Term] +id: GO:0015982 +name: obsolete antiport +namespace: biological_process +def: "OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction." [ISBN:0198506732] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "antiport" EXACT [] +is_obsolete: true +replaced_by: GO:0015297 + +[Term] +id: GO:0015983 +name: obsolete symport +namespace: biological_process +def: "OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction." [ISBN:0198506732] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "symport" EXACT [] +is_obsolete: true +replaced_by: GO:0015293 + +[Term] +id: GO:0015984 +name: obsolete uniport +namespace: biological_process +def: "OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion." [ISBN:0198506732] +comment: This term was made obsolete because it represents a molecular function rather than a biological process. +synonym: "uniport" EXACT [] +is_obsolete: true +replaced_by: GO:0015292 + +[Term] +id: GO:0015985 +name: energy coupled proton transport, down electrochemical gradient +namespace: biological_process +def: "The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP." [GOC:mah] +is_a: GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0015986 +name: ATP synthesis coupled proton transport +namespace: biological_process +def: "The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis." [ISBN:0716731363] +synonym: "chemiosmosis" BROAD [GOC:rs] +is_a: GO:0006754 ! ATP biosynthetic process +is_a: GO:0015985 ! energy coupled proton transport, down electrochemical gradient + +[Term] +id: GO:0015987 +name: GTP synthesis coupled proton transport +namespace: biological_process +def: "The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis." [ISBN:0716731363] +is_a: GO:0015985 ! energy coupled proton transport, down electrochemical gradient + +[Term] +id: GO:0015988 +name: energy coupled proton transmembrane transport, against electrochemical gradient +namespace: biological_process +def: "The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport." [GOC:mah] +is_a: GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0015989 +name: light-driven proton transport +namespace: biological_process +def: "The transport of protons against an electrochemical gradient, using energy from light." [GOC:mah] +is_a: GO:0015988 ! energy coupled proton transmembrane transport, against electrochemical gradient + +[Term] +id: GO:0015990 +name: electron transport coupled proton transport +namespace: biological_process +def: "The transport of protons against an electrochemical gradient, using energy from electron transport." [GOC:mah] +is_a: GO:0015988 ! energy coupled proton transmembrane transport, against electrochemical gradient + +[Term] +id: GO:0015993 +name: obsolete molecular hydrogen transport +namespace: biological_process +def: "OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +comment: The reason for obsoletion is that there molecular hydrogen (H2) diffuses passively through membranes (see https://www.researchgate.net/post/How_molecular_hydrogen_is_transported_through_the_cytoplasmic_membrane_of_Escherichia_coli). +is_obsolete: true + +[Term] +id: GO:0015994 +name: chlorophyll metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment." [GOC:jl] +synonym: "chlorophyll metabolism" EXACT [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0015995 +name: chlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors." [GOC:jl] +synonym: "chlorophyll anabolism" EXACT [] +synonym: "chlorophyll biosynthesis" EXACT [] +synonym: "chlorophyll formation" EXACT [] +synonym: "chlorophyll synthesis" EXACT [] +xref: MetaCyc:CHLOROPHYLL-SYN +is_a: GO:0006779 ! porphyrin-containing compound biosynthetic process +is_a: GO:0015994 ! chlorophyll metabolic process +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0015996 +name: chlorophyll catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products." [GOC:jl] +synonym: "chlorophyll breakdown" EXACT [] +synonym: "chlorophyll catabolism" EXACT [] +synonym: "chlorophyll degradation" EXACT [] +is_a: GO:0006787 ! porphyrin-containing compound catabolic process +is_a: GO:0015994 ! chlorophyll metabolic process +is_a: GO:0046149 ! pigment catabolic process + +[Term] +id: GO:0015997 +name: obsolete ubiquinone biosynthetic process monooxygenase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it incorporates biological process information. +synonym: "coenzyme Q biosynthesis monooxygenase activity" EXACT [] +synonym: "coenzyme Q biosynthetic process monooxygenase activity" EXACT [] +synonym: "ubiquinone anabolism monooxygenase activity" EXACT [] +synonym: "ubiquinone biosynthetic process monooxygenase activity" EXACT [] +synonym: "ubiquinone formation monooxygenase activity" EXACT [] +synonym: "ubiquinone synthesis monooxygenase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0016002 +name: sulfite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor." [RHEA:10547] +synonym: "assimilatory sulfite reductase activity" EXACT [] +synonym: "assimilatory-type sulfite reductase activity" EXACT [] +synonym: "hydrogen-sulfide:(acceptor) oxidoreductase activity" EXACT [] +synonym: "hydrogen-sulfide:acceptor oxidoreductase activity" EXACT [] +synonym: "siroheme sulfite reductase activity" NARROW [MetaCyc:SULFITE-REDUCTASE-RXN] +synonym: "sulphite reductase activity" EXACT [] +xref: MetaCyc:SULFITE-REDUCTASE-RXN +xref: RHEA:10547 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016004 +name: phospholipase activator activity +namespace: molecular_function +def: "Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai] +is_a: GO:0060229 ! lipase activator activity +relationship: positively_regulates GO:0004620 ! phospholipase activity + +[Term] +id: GO:0016005 +name: phospholipase A2 activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme phospholipase A2." [GOC:ai] +is_a: GO:0016004 ! phospholipase activator activity +relationship: positively_regulates GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0016006 +name: Nebenkern +namespace: cellular_component +def: "A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme." [GOC:ma] +is_a: GO:0005739 ! mitochondrion + +[Term] +id: GO:0016007 +name: mitochondrial derivative +namespace: cellular_component +def: "The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation." [GOC:ma] +is_a: GO:0005739 ! mitochondrion + +[Term] +id: GO:0016008 +name: major mitochondrial derivative +namespace: cellular_component +def: "The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative." [GOC:mah, PMID:17123504] +is_a: GO:0016007 ! mitochondrial derivative + +[Term] +id: GO:0016009 +name: minor mitochondrial derivative +namespace: cellular_component +def: "The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation." [GOC:mah, PMID:17123504] +is_a: GO:0016007 ! mitochondrial derivative + +[Term] +id: GO:0016010 +name: dystrophin-associated glycoprotein complex +namespace: cellular_component +def: "A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase." [PMID:15117830, PMID:16710609] +subset: goslim_pir +synonym: "DGC" EXACT [] +synonym: "dystrophin glycoprotein complex" EXACT [] +is_a: GO:0090665 ! glycoprotein complex +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0016011 +name: dystroglycan complex +namespace: cellular_component +def: "A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin." [PMID:15117830, PMID:16710609] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0016010 ! dystrophin-associated glycoprotein complex + +[Term] +id: GO:0016012 +name: sarcoglycan complex +namespace: cellular_component +def: "A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex." [PMID:15117830, PMID:16710609] +synonym: "sarcoglycan-sarcospan complex" EXACT [] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0016011 ! dystroglycan complex + +[Term] +id: GO:0016013 +name: syntrophin complex +namespace: cellular_component +def: "A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase." [http://www.dmd.nl/DGC.html#syn] +synonym: "nitric oxide synthase-dystrophin complex, skeletal muscle" RELATED [CORUM:416] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0016010 ! dystrophin-associated glycoprotein complex + +[Term] +id: GO:0016014 +name: dystrobrevin complex +namespace: cellular_component +def: "A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex." [PMID:15117830, PMID:16710609] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0016010 ! dystrophin-associated glycoprotein complex + +[Term] +id: GO:0016015 +name: morphogen activity +namespace: molecular_function +def: "Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient." [GOC:go_curators] +is_a: GO:0048018 ! receptor ligand activity + +[Term] +id: GO:0016016 +name: obsolete short-wave-sensitive opsin +namespace: molecular_function +def: "OBSOLETE. An opsin with maximal absorption between 400 and 500 nm." [PMID:10594055] +comment: This term was made obsolete because it refers to a class of proteins. +synonym: "short-wave-sensitive opsin" EXACT [] +is_obsolete: true +consider: GO:0007603 +consider: GO:0009588 +consider: GO:0009881 +consider: GO:0016021 +consider: GO:0016918 +consider: GO:0046876 + +[Term] +id: GO:0016018 +name: cyclosporin A binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids." [GOC:mb] +synonym: "cyclophilin" RELATED [] +is_a: GO:0008144 ! drug binding +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0016019 +name: peptidoglycan immune receptor activity +namespace: molecular_function +def: "Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response." [PMID:14698226] +comment: Note that only peptidoglycan recognition proteins with receptor activity should be annotated to this term; otherwise use 'peptidoglycan binding ; GO:0042834' instead. +synonym: "peptidoglycan receptor activity" BROAD [] +synonym: "peptidoglycan recognition activity" NARROW [] +is_a: GO:0038187 ! pattern recognition receptor activity +relationship: has_part GO:0042834 ! peptidoglycan binding + +[Term] +id: GO:0016020 +name: membrane +namespace: cellular_component +def: "A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: Wikipedia:Biological_membrane +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0016021 +name: integral component of membrane +namespace: cellular_component +def: "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] +subset: goslim_chembl +synonym: "integral to membrane" NARROW [] +synonym: "transmembrane" RELATED [GOC:mah] +xref: Wikipedia:Transmembrane_protein +is_a: GO:0031224 ! intrinsic component of membrane + +[Term] +id: GO:0016024 +name: CDP-diacylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate." [PMID:24533860] +synonym: "CDP-diacylglycerol anabolism" EXACT [] +synonym: "CDP-diacylglycerol biosynthesis" EXACT [] +synonym: "CDP-diacylglycerol formation" EXACT [] +synonym: "CDP-diacylglycerol synthesis" EXACT [] +is_a: GO:0006221 ! pyrimidine nucleotide biosynthetic process +is_a: GO:0046341 ! CDP-diacylglycerol metabolic process +is_a: GO:0046474 ! glycerophospholipid biosynthetic process + +[Term] +id: GO:0016025 +name: obsolete proteasome endopeptidase regulator +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "proteasome endopeptidase regulator" EXACT [] +is_obsolete: true +consider: GO:0004175 + +[Term] +id: GO:0016026 +name: obsolete proteasome endopeptidase core +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "proteasome endopeptidase core" EXACT [] +is_obsolete: true +consider: GO:0004175 + +[Term] +id: GO:0016027 +name: inaD signaling complex +namespace: cellular_component +def: "A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD." [GOC:hb, PMID:9010208, PMID:9796815] +synonym: "inaD signalling complex" EXACT [] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0016028 ! rhabdomere +relationship: part_of GO:0019897 ! extrinsic component of plasma membrane + +[Term] +id: GO:0016028 +name: rhabdomere +namespace: cellular_component +def: "The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction." [GOC:hb, GOC:sart, PMID:8646774] +subset: goslim_pir +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0016029 +name: subrhabdomeral cisterna +namespace: cellular_component +def: "A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase." [PMID:11707492, PMID:8646774] +synonym: "SMC" RELATED [] +synonym: "submicrovillar cisterna" EXACT [PMID:11707492] +is_a: GO:0098827 ! endoplasmic reticulum subcompartment +is_a: GO:0120082 ! smooth endoplasmic reticulum cisterna +relationship: part_of GO:0016028 ! rhabdomere + +[Term] +id: GO:0016031 +name: tRNA import into mitochondrion +namespace: biological_process +def: "The process in which a tRNA is transported from the cytosol, into the mitochondrial matrix." [GOC:ma, PMID:10988073, PMID:11121736] +synonym: "cytoplasmic tRNA import into mitochondria" EXACT [] +synonym: "cytoplasmic tRNA import into mitochondrion" NARROW [GOC:bf] +synonym: "cytoplasmic tRNA transport into mitochondrion" EXACT [] +synonym: "cytoplasmic tRNA, mitochondrial import" EXACT [] +synonym: "mitochondrial import of cytoplasmic tRNA" NARROW [] +synonym: "nuclear-encoded tRNA import into mitochondrion" NARROW [GOC:bf] +is_a: GO:0035927 ! RNA import into mitochondrion +is_a: GO:0051031 ! tRNA transport + +[Term] +id: GO:0016032 +name: viral process +namespace: biological_process +alt_id: GO:0022415 +def: "A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle." [GOC:bf, GOC:jl, GOC:mah] +comment: See also the biological process terms 'viral infectious cycle ; GO:0019058' and 'lysogeny ; GO:0030069'. +subset: goslim_metagenomics +subset: goslim_pir +synonym: "viral infection" RELATED [] +synonym: "virulence" RELATED [] +synonym: "virus process" EXACT [GOC:bf, GOC:jl] +xref: Wikipedia:Viral_life_cycle +is_a: GO:0044403 ! symbiotic process +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0016034 +name: maleylacetoacetate isomerase activity +namespace: molecular_function +alt_id: GO:0018841 +def: "Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate." [EC:5.2.1.2] +synonym: "4-maleylacetoacetate cis-trans-isomerase activity" EXACT [EC:5.2.1.2] +synonym: "maleylacetoacetic isomerase activity" EXACT [EC:5.2.1.2] +synonym: "maleylacetone cis-trans-isomerase activity" EXACT [EC:5.2.1.2] +synonym: "maleylacetone isomerase activity" EXACT [EC:5.2.1.2] +xref: EC:5.2.1.2 +xref: MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN +xref: Reactome:R-HSA-71173 "maleylacetoacetate => fumarylacetoacetate" +xref: RHEA:14817 +xref: UM-BBD_reactionID:r0106 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0016035 +name: zeta DNA polymerase complex +namespace: cellular_component +def: "A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer." [PMID:16631579, PMID:16971464] +is_a: GO:0042575 ! DNA polymerase complex +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0016036 +name: cellular response to phosphate starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate." [GOC:jl] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0016037 +name: light absorption +namespace: biological_process +def: "The reception of a photon by a cell." [GOC:go_curators] +synonym: "absorption of light" EXACT [] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0009583 ! detection of light stimulus + +[Term] +id: GO:0016038 +name: absorption of visible light +namespace: biological_process +def: "The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0016037 ! light absorption + +[Term] +id: GO:0016039 +name: absorption of UV light +namespace: biological_process +def: "The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0016037 ! light absorption + +[Term] +id: GO:0016040 +name: glutamate synthase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH." [EC:1.4.1.14, RHEA:13753] +synonym: "glutamate (reduced nicotinamide adenine dinucleotide) synthase" EXACT [EC:1.4.1.14] +synonym: "GOGAT activity" BROAD [] +synonym: "L-glutamate synthase (NADH)" EXACT [EC:1.4.1.14] +synonym: "L-glutamate synthase activity" BROAD [EC:1.4.1.14] +synonym: "L-glutamate synthetase activity" BROAD [EC:1.4.1.14] +synonym: "L-glutamate:NAD+ oxidoreductase (transaminating)" EXACT [EC:1.4.1.14] +synonym: "NADH-dependent glutamate synthase activity" EXACT [EC:1.4.1.14] +synonym: "NADH-glutamate synthase activity" EXACT [EC:1.4.1.14] +synonym: "NADH: GOGAT" EXACT [EC:1.4.1.14] +xref: EC:1.4.1.14 +xref: KEGG_REACTION:R00093 +xref: MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN +xref: RHEA:13753 +is_a: GO:0045181 ! glutamate synthase activity, NAD(P)H as acceptor + +[Term] +id: GO:0016041 +name: glutamate synthase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+." [EC:1.4.7.1] +synonym: "ferredoxin-dependent glutamate synthase activity" EXACT [EC:1.4.7.1] +synonym: "ferredoxin-glutamate synthase activity" EXACT [EC:1.4.7.1] +synonym: "glutamate synthase (ferredoxin-dependent)" EXACT [EC:1.4.7.1] +synonym: "L-glutamate:ferredoxin oxidoreductase (transaminating)" EXACT [EC:1.4.7.1] +xref: EC:1.4.7.1 +xref: MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN +xref: MetaCyc:PWY-4341 +is_a: GO:0015930 ! glutamate synthase activity +is_a: GO:0016643 ! oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0016042 +name: lipid catabolic process +namespace: biological_process +alt_id: GO:0006724 +alt_id: GO:0044240 +def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] +synonym: "lipid breakdown" EXACT [] +synonym: "lipid catabolism" EXACT [] +synonym: "lipid degradation" EXACT [] +synonym: "lipolysis" EXACT [] +synonym: "multicellular organism lipid catabolic process" NARROW [] +synonym: "multicellular organismal lipid catabolic process" NARROW [] +xref: Wikipedia:Lipid_catabolism +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0016043 +name: cellular component organization +namespace: biological_process +alt_id: GO:0044235 +alt_id: GO:0071842 +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah] +subset: goslim_agr +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +synonym: "cell organisation" EXACT [] +synonym: "cell organization and biogenesis" RELATED [GOC:mah] +synonym: "cellular component organisation at cellular level" EXACT [GOC:mah] +synonym: "cellular component organisation in other organism" EXACT [GOC:mah] +synonym: "cellular component organization at cellular level" EXACT [] +synonym: "cellular component organization in other organism" EXACT [] +is_a: GO:0071840 ! cellular component organization or biogenesis + +[Term] +id: GO:0016045 +name: detection of bacterium +namespace: biological_process +alt_id: GO:0009598 +alt_id: GO:0009681 +def: "The series of events in which a stimulus from a bacterium is received and converted into a molecular signal." [GOC:hb] +synonym: "detection of bacteria" EXACT [] +synonym: "perception of bacteria" RELATED [] +synonym: "perception of bacterium" RELATED [] +is_a: GO:0009617 ! response to bacterium +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0016046 +name: detection of fungus +namespace: biological_process +alt_id: GO:0009599 +alt_id: GO:0016047 +def: "The series of events in which a stimulus from a fungus is received and converted into a molecular signal." [GOC:hb] +synonym: "detection of fungi" EXACT [] +synonym: "detection of parasitic fungi" NARROW [] +synonym: "detection of parasitic fungus" NARROW [] +synonym: "perception of fungi" RELATED [] +synonym: "perception of fungus" RELATED [] +synonym: "perception of parasitic fungi" NARROW [] +synonym: "perception of parasitic fungus" RELATED [] +is_a: GO:0009620 ! response to fungus +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0016048 +name: detection of temperature stimulus +namespace: biological_process +def: "The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal." [GOC:hb] +synonym: "detection of temperature" EXACT [] +synonym: "detection of thermal stimulus" EXACT [] +synonym: "perception of temperature" RELATED [] +is_a: GO:0009266 ! response to temperature stimulus +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009582 ! detection of abiotic stimulus + +[Term] +id: GO:0016049 +name: cell growth +namespace: biological_process +alt_id: GO:0048591 +def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] +subset: gocheck_do_not_annotate +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_plant +synonym: "cell expansion" RELATED [] +synonym: "cellular growth" EXACT [] +synonym: "growth of cell" EXACT [] +synonym: "metabolic process resulting in cell growth" RELATED [] +synonym: "metabolism resulting in cell growth" RELATED [] +synonym: "non-developmental cell growth" RELATED [GOC:mah] +synonym: "non-developmental growth of a unicellular organism" RELATED [GOC:mah] +is_a: GO:0009987 ! cellular process +is_a: GO:0040007 ! growth + +[Term] +id: GO:0016050 +name: vesicle organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah] +subset: goslim_pir +subset: goslim_yeast +synonym: "vesicle organisation" EXACT [] +synonym: "vesicle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0016051 +name: carbohydrate biosynthetic process +namespace: biological_process +alt_id: GO:0006093 +def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] +synonym: "anabolic carbohydrate metabolic process" EXACT [] +synonym: "anabolic carbohydrate metabolism" EXACT [] +synonym: "carbohydrate anabolism" EXACT [] +synonym: "carbohydrate biosynthesis" EXACT [] +synonym: "carbohydrate formation" EXACT [] +synonym: "carbohydrate synthesis" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0016052 +name: carbohydrate catabolic process +namespace: biological_process +alt_id: GO:0006095 +alt_id: GO:0044276 +alt_id: GO:0044724 +def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] +synonym: "carbohydrate breakdown" EXACT [] +synonym: "carbohydrate catabolism" EXACT [] +synonym: "carbohydrate degradation" EXACT [] +synonym: "catabolic carbohydrate metabolic process" EXACT [] +synonym: "catabolic carbohydrate metabolism" EXACT [] +synonym: "multicellular organismal carbohydrate catabolic process" NARROW [] +synonym: "single-organism carbohydrate catabolic process" RELATED [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: jl +creation_date: 2012-10-23T16:34:39Z + +[Term] +id: GO:0016053 +name: organic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] +synonym: "organic acid anabolism" EXACT [] +synonym: "organic acid biosynthesis" EXACT [] +synonym: "organic acid formation" EXACT [] +synonym: "organic acid synthesis" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0016054 +name: organic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] +synonym: "organic acid breakdown" EXACT [] +synonym: "organic acid catabolism" EXACT [] +synonym: "organic acid degradation" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0016055 +name: Wnt signaling pathway +namespace: biological_process +alt_id: GO:0007222 +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state." [GOC:dph, GOC:go_curators, PMID:11532397] +synonym: "frizzled signaling pathway" EXACT [] +synonym: "frizzled signalling pathway" EXACT [] +synonym: "Wg signaling pathway" EXACT [GOC:sart, PMID:8080429] +synonym: "Wg signalling pathway" EXACT [GOC:sart, PMID:8080429] +synonym: "Wingless signaling pathway" EXACT [GOC:sart, PMID:8080429] +synonym: "Wingless signalling pathway" EXACT [GOC:sart, PMID:8080429] +synonym: "Wnt receptor signaling pathway" EXACT [GOC:signaling] +synonym: "Wnt receptor signalling pathway" EXACT [] +synonym: "Wnt-activated signaling pathway" RELATED [] +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +relationship: part_of GO:0198738 ! cell-cell signaling by wnt + +[Term] +id: GO:0016056 +name: rhodopsin mediated signaling pathway +namespace: biological_process +alt_id: GO:0009586 +def: "The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response." [GOC:bf, GOC:dph, GOC:hb, GOC:signaling, GOC:tb] +synonym: "rhodopsin mediated phototransduction" EXACT [GOC:bf] +synonym: "rhodopsin mediated signalling pathway" EXACT [GOC:dph, GOC:tb] +synonym: "rhodopsin signaling" EXACT [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0007602 ! phototransduction +is_a: GO:0071482 ! cellular response to light stimulus +relationship: part_of GO:0007603 ! phototransduction, visible light + +[Term] +id: GO:0016057 +name: regulation of membrane potential in photoreceptor cell +namespace: biological_process +def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] +synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0016058 +name: maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling +namespace: biological_process +def: "Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] +synonym: "maintenance of rhodopsin mediated signaling" RELATED [] +synonym: "maintenance of rhodopsin mediated signalling" EXACT [] +is_a: GO:0016057 ! regulation of membrane potential in photoreceptor cell + +[Term] +id: GO:0016059 +name: deactivation of rhodopsin mediated signaling +namespace: biological_process +def: "The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon)." [PMID:8316831] +synonym: "deactivation of rhodopsin mediated signalling" EXACT [] +synonym: "rod response recovery" BROAD [GOC:bf] +is_a: GO:0022400 ! regulation of rhodopsin mediated signaling pathway + +[Term] +id: GO:0016060 +name: metarhodopsin inactivation +namespace: biological_process +def: "The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it." [GOC:hb, Wikipedia:Visual_phototransduction] +is_a: GO:0009968 ! negative regulation of signal transduction +relationship: has_part GO:0004703 ! G protein-coupled receptor kinase activity +relationship: part_of GO:0016059 ! deactivation of rhodopsin mediated signaling + +[Term] +id: GO:0016061 +name: regulation of light-activated channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of light-activated channel activity." [GOC:go_curators] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010461 ! light-activated ion channel activity +relationship: regulates GO:0010461 ! light-activated ion channel activity + +[Term] +id: GO:0016062 +name: adaptation of rhodopsin mediated signaling +namespace: biological_process +def: "The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation." [PMID:1962207] +synonym: "adaptation of rhodopsin mediated signalling" EXACT [] +is_a: GO:0023058 ! adaptation of signaling pathway +relationship: part_of GO:0016056 ! rhodopsin mediated signaling pathway +relationship: part_of GO:0036367 ! light adaption + +[Term] +id: GO:0016063 +name: rhodopsin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas." [ISBN:0198506732] +synonym: "rhodopsin anabolism" EXACT [] +synonym: "rhodopsin biosynthesis" EXACT [] +synonym: "rhodopsin formation" EXACT [] +synonym: "rhodopsin synthesis" EXACT [] +is_a: GO:0006726 ! eye pigment biosynthetic process +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0046154 ! rhodopsin metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0016064 +name: immunoglobulin mediated immune response +namespace: biological_process +def: "An immune response mediated by immunoglobulins, whether cell-bound or in solution." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "antibody-mediated immune response" EXACT [] +is_a: GO:0019724 ! B cell mediated immunity + +[Term] +id: GO:0016065 +name: obsolete humoral defense mechanism (sensu Protostomia) +namespace: biological_process +def: "OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317)." [GOC:add, GOC:jid] +comment: This term was made obsolete because antibodies are not found in the taxon Protostomia. +synonym: "humoral defence mechanism (sensu Protostomia)" EXACT [] +synonym: "humoral defense mechanism (sensu Protostomia)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0016068 +name: type I hypersensitivity +namespace: biological_process +def: "An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines." [GOC:add, ISBN:0781735149] +comment: Note that localized and systemic anaphylaxis is usually a result of type I hypersensitivity. +synonym: "immediate hypersensitivity response" EXACT [] +xref: Wikipedia:Type_I_hypersensitivity +is_a: GO:0002524 ! hypersensitivity +is_a: GO:0016064 ! immunoglobulin mediated immune response + +[Term] +id: GO:0016070 +name: RNA metabolic process +namespace: biological_process +def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_metagenomics +subset: goslim_pir +synonym: "RNA metabolism" EXACT [] +is_a: GO:0090304 ! nucleic acid metabolic process + +[Term] +id: GO:0016071 +name: mRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pombe +synonym: "mRNA metabolism" EXACT [] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0016072 +name: rRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes." [ISBN:0198506732] +subset: goslim_drosophila +synonym: "rRNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0016073 +name: snRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein." [ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pombe +synonym: "snRNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0016074 +name: snoRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA." [GOC:krc] +subset: goslim_drosophila +subset: goslim_pombe +synonym: "snoRNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0016075 +name: rRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes." [GOC:ai] +synonym: "rRNA breakdown" EXACT [] +synonym: "rRNA catabolism" EXACT [] +synonym: "rRNA degradation" EXACT [] +is_a: GO:0016072 ! rRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0016076 +name: snRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein." [ISBN:0198506732] +synonym: "snRNA breakdown" EXACT [] +synonym: "snRNA catabolism" EXACT [] +synonym: "snRNA degradation" EXACT [] +is_a: GO:0016073 ! snRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0016077 +name: snoRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins." [ISBN:0198506732] +synonym: "snoRNA breakdown" EXACT [] +synonym: "snoRNA catabolism" EXACT [] +synonym: "snoRNA degradation" EXACT [] +is_a: GO:0016074 ! snoRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0016078 +name: tRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis." [GOC:ai] +synonym: "tRNA breakdown" EXACT [] +synonym: "tRNA catabolism" EXACT [] +synonym: "tRNA degradation" EXACT [] +is_a: GO:0006399 ! tRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0016079 +name: synaptic vesicle exocytosis +namespace: biological_process +def: "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft." [GOC:jid, GOC:lmg] +subset: goslim_synapse +is_a: GO:0045055 ! regulated exocytosis +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099003 ! vesicle-mediated transport in synapse +is_a: GO:0099643 ! signal release from synapse +intersection_of: GO:0045055 ! regulated exocytosis +intersection_of: occurs_in GO:0098793 ! presynapse +relationship: occurs_in GO:0098793 ! presynapse +relationship: part_of GO:0007269 ! neurotransmitter secretion +relationship: part_of GO:0099504 ! synaptic vesicle cycle + +[Term] +id: GO:0016080 +name: synaptic vesicle targeting +namespace: biological_process +def: "The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:mah] +is_a: GO:0006903 ! vesicle targeting +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0016081 +name: synaptic vesicle docking +namespace: biological_process +def: "The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process." [PMID:15217342] +comment: Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015). +subset: goslim_synapse +synonym: "synaptic vesicle docking during exocytosis" RELATED [GOC:dph, GOC:tb] +synonym: "synaptic vesicle docking involved in exocytosis" EXACT [] +is_a: GO:0006904 ! vesicle docking involved in exocytosis +intersection_of: GO:0006904 ! vesicle docking involved in exocytosis +intersection_of: part_of GO:0016079 ! synaptic vesicle exocytosis +relationship: part_of GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0016082 +name: synaptic vesicle priming +namespace: biological_process +def: "A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane." [GOC:mah, PMID:15217342, PMID:23060190] +comment: Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission. (dos, pvn, fk synapse project 2015) +subset: goslim_synapse +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0016083 +name: obsolete synaptic vesicle fusion +namespace: biological_process +def: "OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane." [GOC:curators] +comment: This term was made obsolete because it was wrongly defined. +synonym: "synaptic vesicle fusion" EXACT [] +is_obsolete: true +consider: GO:0016192 + +[Term] +id: GO:0016084 +name: myostimulatory hormone activity +namespace: molecular_function +def: "The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction." [GOC:mah, PMID:12204246] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0016085 +name: myoinhibitory hormone activity +namespace: molecular_function +def: "The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction." [GOC:mah, PMID:8902848] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0016086 +name: obsolete allatostatin +namespace: molecular_function +def: "OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone." [GOC:ai, PMID:10891383] +comment: This term was made obsolete because it refers to a gene product. +synonym: "allatostatin" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0045968 + +[Term] +id: GO:0016087 +name: ecdysiostatic hormone activity +namespace: molecular_function +def: "The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion." [DOI:10.1002/(SICI)1520-6327(1997)35\:1, GOC:mah] +is_a: GO:0005184 ! neuropeptide hormone activity + +[Term] +id: GO:0016088 +name: obsolete insulin +namespace: molecular_function +def: "OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "insulin" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0045722 +consider: GO:0045727 +consider: GO:0045935 +consider: GO:0046326 +consider: GO:0046889 + +[Term] +id: GO:0016090 +name: prenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail." [ISBN:0198547684] +synonym: "prenol metabolism" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0016091 +name: prenol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail." [GOC:go_curators] +synonym: "prenol anabolism" EXACT [] +synonym: "prenol biosynthesis" EXACT [] +synonym: "prenol formation" EXACT [] +synonym: "prenol synthesis" EXACT [] +is_a: GO:0008299 ! isoprenoid biosynthetic process +is_a: GO:0016090 ! prenol metabolic process +is_a: GO:0046165 ! alcohol biosynthetic process + +[Term] +id: GO:0016092 +name: prenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail." [GOC:go_curators] +synonym: "prenol breakdown" EXACT [] +synonym: "prenol catabolism" EXACT [] +synonym: "prenol degradation" EXACT [] +is_a: GO:0008300 ! isoprenoid catabolic process +is_a: GO:0016090 ! prenol metabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0016093 +name: polyprenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans." [PMID:11108713] +synonym: "polyprenol metabolism" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0016094 +name: polyprenol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans." [GOC:go_curators, PMID:11108713] +synonym: "polyprenol anabolism" EXACT [] +synonym: "polyprenol biosynthesis" EXACT [] +synonym: "polyprenol formation" EXACT [] +synonym: "polyprenol synthesis" EXACT [] +is_a: GO:0008299 ! isoprenoid biosynthetic process +is_a: GO:0016093 ! polyprenol metabolic process +is_a: GO:0046165 ! alcohol biosynthetic process + +[Term] +id: GO:0016095 +name: polyprenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans." [GOC:go_curators, Wikipedia:Polyprenol] +synonym: "polyprenol breakdown" EXACT [] +synonym: "polyprenol catabolism" EXACT [] +synonym: "polyprenol degradation" EXACT [] +is_a: GO:0008300 ! isoprenoid catabolic process +is_a: GO:0016093 ! polyprenol metabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0016098 +name: monoterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton." [ISBN:0198547684] +synonym: "monoterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0016099 +name: monoterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton." [GOC:go_curators] +synonym: "monoterpenoid anabolism" EXACT [] +synonym: "monoterpenoid biosynthesis" EXACT [] +synonym: "monoterpenoid formation" EXACT [] +synonym: "monoterpenoid synthesis" EXACT [] +xref: MetaCyc:PWY-3041 +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016100 +name: monoterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton." [GOC:go_curators] +synonym: "monoterpenoid breakdown" EXACT [] +synonym: "monoterpenoid catabolism" EXACT [] +synonym: "monoterpenoid degradation" EXACT [] +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016101 +name: diterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units." [ISBN:0198547684] +synonym: "diterpene metabolic process" NARROW [] +synonym: "diterpene metabolism" NARROW [] +synonym: "diterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0016102 +name: diterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units." [GOC:mah, ISBN:0198547684] +synonym: "diterpene biosynthesis" NARROW [] +synonym: "diterpene biosynthetic process" NARROW [] +synonym: "diterpenoid anabolism" EXACT [] +synonym: "diterpenoid biosynthesis" EXACT [] +synonym: "diterpenoid formation" EXACT [] +synonym: "diterpenoid synthesis" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016103 +name: diterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units." [GOC:mah, ISBN:0198547684] +synonym: "diterpene catabolic process" NARROW [] +synonym: "diterpene catabolism" NARROW [] +synonym: "diterpenoid breakdown" EXACT [] +synonym: "diterpenoid catabolism" EXACT [] +synonym: "diterpenoid degradation" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016104 +name: triterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units." [GOC:go_curators] +synonym: "triterpene biosynthesis" NARROW [] +synonym: "triterpene biosynthetic process" NARROW [] +synonym: "triterpenoid anabolism" EXACT [] +synonym: "triterpenoid biosynthesis" EXACT [] +synonym: "triterpenoid formation" EXACT [] +synonym: "triterpenoid synthesis" EXACT [] +is_a: GO:0006722 ! triterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016105 +name: triterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units." [GOC:go_curators] +synonym: "triterpene catabolic process" NARROW [] +synonym: "triterpene catabolism" NARROW [] +synonym: "triterpenoid breakdown" EXACT [] +synonym: "triterpenoid catabolism" EXACT [] +synonym: "triterpenoid degradation" EXACT [] +is_a: GO:0006722 ! triterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016106 +name: sesquiterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units." [GOC:go_curators] +synonym: "sesquiterpenoid anabolism" EXACT [] +synonym: "sesquiterpenoid biosynthesis" EXACT [] +synonym: "sesquiterpenoid formation" EXACT [] +synonym: "sesquiterpenoid synthesis" EXACT [] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016107 +name: sesquiterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units." [GOC:go_curators] +synonym: "sesquiterpenoid breakdown" EXACT [] +synonym: "sesquiterpenoid catabolism" EXACT [] +synonym: "sesquiterpenoid degradation" EXACT [] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016108 +name: tetraterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units." [ISBN:0198547684] +synonym: "tetraterpene metabolic process" NARROW [] +synonym: "tetraterpene metabolism" NARROW [] +synonym: "tetraterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0016109 +name: tetraterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units." [GOC:go_curators] +synonym: "tetraterpene biosynthesis" NARROW [] +synonym: "tetraterpene biosynthetic process" NARROW [] +synonym: "tetraterpenoid anabolism" EXACT [] +synonym: "tetraterpenoid biosynthesis" EXACT [] +synonym: "tetraterpenoid formation" EXACT [] +synonym: "tetraterpenoid synthesis" EXACT [] +is_a: GO:0016108 ! tetraterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016110 +name: tetraterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units." [GOC:go_curators] +synonym: "tetraterpene catabolic process" NARROW [] +synonym: "tetraterpene catabolism" NARROW [] +synonym: "tetraterpenoid breakdown" EXACT [] +synonym: "tetraterpenoid catabolism" EXACT [] +synonym: "tetraterpenoid degradation" EXACT [] +is_a: GO:0016108 ! tetraterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016111 +name: polyterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units." [ISBN:0198547684] +synonym: "polyterpene metabolic process" NARROW [] +synonym: "polyterpene metabolism" NARROW [] +synonym: "polyterpenoid metabolism" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0016112 +name: polyterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units." [GOC:go_curators] +synonym: "polyterpene biosynthesis" NARROW [] +synonym: "polyterpene biosynthetic process" NARROW [] +synonym: "polyterpenoid anabolism" EXACT [] +synonym: "polyterpenoid biosynthesis" EXACT [] +synonym: "polyterpenoid formation" EXACT [] +synonym: "polyterpenoid synthesis" EXACT [] +is_a: GO:0016111 ! polyterpenoid metabolic process +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0016113 +name: polyterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units." [GOC:go_curators] +synonym: "polyterpene catabolic process" NARROW [] +synonym: "polyterpene catabolism" NARROW [] +synonym: "polyterpenoid breakdown" EXACT [] +synonym: "polyterpenoid catabolism" EXACT [] +synonym: "polyterpenoid degradation" EXACT [] +is_a: GO:0016111 ! polyterpenoid metabolic process +is_a: GO:0016115 ! terpenoid catabolic process + +[Term] +id: GO:0016114 +name: terpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." [GOC:ai] +synonym: "terpenoid anabolism" EXACT [] +synonym: "terpenoid biosynthesis" EXACT [] +synonym: "terpenoid formation" EXACT [] +synonym: "terpenoid synthesis" EXACT [] +xref: Wikipedia:Terpenoid +is_a: GO:0006721 ! terpenoid metabolic process +is_a: GO:0008299 ! isoprenoid biosynthetic process + +[Term] +id: GO:0016115 +name: terpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure." [GOC:ai] +synonym: "terpenoid breakdown" EXACT [] +synonym: "terpenoid catabolism" EXACT [] +synonym: "terpenoid degradation" EXACT [] +is_a: GO:0006721 ! terpenoid metabolic process +is_a: GO:0008300 ! isoprenoid catabolic process + +[Term] +id: GO:0016116 +name: carotenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail." [ISBN:0198547684] +synonym: "carotenoid metabolism" EXACT [] +is_a: GO:0016108 ! tetraterpenoid metabolic process +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0016117 +name: carotenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail." [GOC:go_curators] +synonym: "carotenoid anabolism" EXACT [] +synonym: "carotenoid biosynthesis" EXACT [] +synonym: "carotenoid formation" EXACT [] +synonym: "carotenoid synthesis" EXACT [] +xref: MetaCyc:CAROTENOID-PWY +is_a: GO:0016109 ! tetraterpenoid biosynthetic process +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0016118 +name: carotenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail." [GOC:go_curators] +synonym: "carotenoid breakdown" EXACT [] +synonym: "carotenoid catabolism" EXACT [] +synonym: "carotenoid degradation" EXACT [] +is_a: GO:0016110 ! tetraterpenoid catabolic process +is_a: GO:0016116 ! carotenoid metabolic process + +[Term] +id: GO:0016119 +name: carotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids." [ISBN:0198547684] +synonym: "carotene metabolism" EXACT [] +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0016120 +name: carotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids." [GOC:go_curators] +synonym: "carotene anabolism" EXACT [] +synonym: "carotene biosynthesis" EXACT [] +synonym: "carotene formation" EXACT [] +synonym: "carotene synthesis" EXACT [] +is_a: GO:0016119 ! carotene metabolic process +is_a: GO:0046246 ! terpene biosynthetic process + +[Term] +id: GO:0016121 +name: carotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids." [GOC:go_curators] +synonym: "carotene breakdown" EXACT [] +synonym: "carotene catabolism" EXACT [] +synonym: "carotene degradation" EXACT [] +is_a: GO:0016119 ! carotene metabolic process +is_a: GO:0046247 ! terpene catabolic process + +[Term] +id: GO:0016122 +name: xanthophyll metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids." [ISBN:0198547684] +synonym: "xanthophyll metabolism" EXACT [] +is_a: GO:0016116 ! carotenoid metabolic process + +[Term] +id: GO:0016123 +name: xanthophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids." [GOC:go_curators] +synonym: "xanthophyll anabolism" EXACT [] +synonym: "xanthophyll biosynthesis" EXACT [] +synonym: "xanthophyll formation" EXACT [] +synonym: "xanthophyll synthesis" EXACT [] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:0016122 ! xanthophyll metabolic process + +[Term] +id: GO:0016124 +name: xanthophyll catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids." [GOC:go_curators] +synonym: "xanthophyll breakdown" EXACT [] +synonym: "xanthophyll catabolism" EXACT [] +synonym: "xanthophyll degradation" EXACT [] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:0016122 ! xanthophyll metabolic process + +[Term] +id: GO:0016125 +name: sterol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [ISBN:0198547684] +synonym: "sterol metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0016126 +name: sterol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:go_curators] +synonym: "sterol anabolism" EXACT [] +synonym: "sterol biosynthesis" EXACT [] +synonym: "sterol formation" EXACT [] +synonym: "sterol synthesis" EXACT [] +xref: MetaCyc:PWY-2541 +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0016127 +name: sterol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:go_curators] +synonym: "sterol breakdown" EXACT [] +synonym: "sterol catabolism" EXACT [] +synonym: "sterol degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0016128 +name: phytosteroid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi." [GOC:mah, ISBN:0198547684] +synonym: "phytosteroid metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0016129 +name: phytosteroid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi." [GOC:go_curators, GOC:mah, ISBN:0471331309] +synonym: "phytosteroid anabolism" EXACT [] +synonym: "phytosteroid biosynthesis" EXACT [] +synonym: "phytosteroid formation" EXACT [] +synonym: "phytosteroid synthesis" EXACT [] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0016128 ! phytosteroid metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0016130 +name: phytosteroid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi." [GOC:go_curators, GOC:mah] +synonym: "phytosteroid breakdown" EXACT [] +synonym: "phytosteroid catabolism" EXACT [] +synonym: "phytosteroid degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0016128 ! phytosteroid metabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0016131 +name: brassinosteroid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects." [ISBN:0192801023] +synonym: "brassinosteroid metabolism" EXACT [] +is_a: GO:0016128 ! phytosteroid metabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0016132 +name: brassinosteroid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects." [ISBN:0192801023] +synonym: "brassinosteroid anabolism" EXACT [] +synonym: "brassinosteroid biosynthesis" EXACT [] +synonym: "brassinosteroid formation" EXACT [] +synonym: "brassinosteroid synthesis" EXACT [] +xref: MetaCyc:PWY-2582 +xref: MetaCyc:PWY-699 +is_a: GO:0016129 ! phytosteroid biosynthetic process +is_a: GO:0016131 ! brassinosteroid metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0016133 +name: brassinosteroid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects." [ISBN:0192801023] +synonym: "brassinosteroid breakdown" EXACT [] +synonym: "brassinosteroid catabolism" EXACT [] +synonym: "brassinosteroid degradation" EXACT [] +is_a: GO:0016130 ! phytosteroid catabolic process +is_a: GO:0016131 ! brassinosteroid metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0016134 +name: saponin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection." [ISBN:0198547684] +synonym: "saponin metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process + +[Term] +id: GO:0016135 +name: saponin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection." [GOC:go_curators] +synonym: "saponin anabolism" EXACT [] +synonym: "saponin biosynthesis" EXACT [] +synonym: "saponin formation" EXACT [] +synonym: "saponin synthesis" EXACT [] +is_a: GO:0016134 ! saponin metabolic process +is_a: GO:0016138 ! glycoside biosynthetic process + +[Term] +id: GO:0016136 +name: saponin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection." [GOC:go_curators] +synonym: "saponin breakdown" EXACT [] +synonym: "saponin catabolism" EXACT [] +synonym: "saponin degradation" EXACT [] +is_a: GO:0016134 ! saponin metabolic process +is_a: GO:0016139 ! glycoside catabolic process + +[Term] +id: GO:0016137 +name: glycoside metabolic process +namespace: biological_process +alt_id: GO:0016140 +def: "The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound." [ISBN:0198547684] +synonym: "glycoside metabolism" EXACT [] +synonym: "O-glycoside metabolic process" EXACT [] +synonym: "O-glycoside metabolism" EXACT [] +is_a: GO:1901657 ! glycosyl compound metabolic process + +[Term] +id: GO:0016138 +name: glycoside biosynthetic process +namespace: biological_process +alt_id: GO:0016141 +def: "The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound." [GOC:go_curators] +synonym: "glycoside anabolism" EXACT [] +synonym: "glycoside biosynthesis" EXACT [] +synonym: "glycoside formation" EXACT [] +synonym: "glycoside synthesis" EXACT [] +synonym: "O-glycoside anabolism" EXACT [] +synonym: "O-glycoside biosynthesis" EXACT [] +synonym: "O-glycoside biosynthetic process" EXACT [] +synonym: "O-glycoside formation" EXACT [] +synonym: "O-glycoside synthesis" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:1901659 ! glycosyl compound biosynthetic process + +[Term] +id: GO:0016139 +name: glycoside catabolic process +namespace: biological_process +alt_id: GO:0016142 +def: "The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound." [GOC:go_curators] +synonym: "glycoside breakdown" EXACT [] +synonym: "glycoside catabolism" EXACT [] +synonym: "glycoside degradation" EXACT [] +synonym: "O-glycoside breakdown" EXACT [] +synonym: "O-glycoside catabolic process" EXACT [] +synonym: "O-glycoside catabolism" EXACT [] +synonym: "O-glycoside degradation" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:1901658 ! glycosyl compound catabolic process + +[Term] +id: GO:0016143 +name: S-glycoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group." [ISBN:0198506732] +synonym: "S-glycoside metabolism" EXACT [] +synonym: "thioglycoside metabolic process" EXACT [] +synonym: "thioglycoside metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:1901657 ! glycosyl compound metabolic process + +[Term] +id: GO:0016144 +name: S-glycoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group." [ISBN:0198506732] +synonym: "S-glycoside anabolism" EXACT [] +synonym: "S-glycoside biosynthesis" EXACT [] +synonym: "S-glycoside formation" EXACT [] +synonym: "S-glycoside synthesis" EXACT [] +synonym: "thioglycoside biosynthesis" EXACT [] +synonym: "thioglycoside biosynthetic process" EXACT [] +is_a: GO:0016143 ! S-glycoside metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901659 ! glycosyl compound biosynthetic process + +[Term] +id: GO:0016145 +name: S-glycoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group." [ISBN:0198506732] +synonym: "S-glycoside breakdown" EXACT [] +synonym: "S-glycoside catabolism" EXACT [] +synonym: "S-glycoside degradation" EXACT [] +synonym: "thioglycoside catabolic process" EXACT [] +synonym: "thioglycoside catabolism" EXACT [] +is_a: GO:0016143 ! S-glycoside metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901658 ! glycosyl compound catabolic process + +[Term] +id: GO:0016146 +name: obsolete protein-synthesizing GTPase activity, initiation +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.48] +comment: This term was made obsolete because it contains both process and function information. +synonym: "protein-synthesizing GTPase activity, initiation" EXACT [] +is_obsolete: true +consider: GO:0003743 +consider: GO:0003924 +consider: GO:0006412 +consider: GO:0006413 + +[Term] +id: GO:0016147 +name: obsolete protein-synthesizing GTPase activity, elongation +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.48] +comment: This term was made obsolete because it contains both process and function information. +synonym: "protein-synthesizing GTPase activity, elongation" EXACT [] +is_obsolete: true +consider: GO:0003746 +consider: GO:0003924 +consider: GO:0006412 +consider: GO:0006414 + +[Term] +id: GO:0016148 +name: obsolete protein-synthesizing GTPase activity, termination +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate." [EC:3.6.1.48] +comment: This term was made obsolete because it contains both process and function information. +synonym: "protein-synthesizing GTPase activity, termination" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0006412 +consider: GO:0006415 +consider: GO:0008079 + +[Term] +id: GO:0016149 +name: translation release factor activity, codon specific +namespace: molecular_function +def: "A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site." [ISBN:0198547684] +is_a: GO:0003747 ! translation release factor activity + +[Term] +id: GO:0016150 +name: translation release factor activity, codon nonspecific +namespace: molecular_function +def: "A translation release factor that is not specific to particular codons; binds to guanine nucleotides." [ISBN:0198547684] +is_a: GO:0003747 ! translation release factor activity + +[Term] +id: GO:0016151 +name: nickel cation binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with nickel (Ni) cations." [GOC:ai] +synonym: "nickel binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0016152 +name: mercury (II) reductase activity +namespace: molecular_function +alt_id: GO:0018692 +def: "Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH." [EC:1.16.1.1, RHEA:23856] +synonym: "Hg:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.1] +synonym: "mer A" RELATED [EC:1.16.1.1] +synonym: "mercurate(II) reductase activity" EXACT [EC:1.16.1.1] +synonym: "mercuric ion reductase activity" EXACT [EC:1.16.1.1] +synonym: "mercuric reductase activity" EXACT [EC:1.16.1.1] +synonym: "mercury reductase activity" EXACT [EC:1.16.1.1] +synonym: "mercury(II) reductase activity" EXACT [EC:1.16.1.1] +synonym: "reduced NADP:mercuric ion oxidoreductase activity" EXACT [EC:1.16.1.1] +xref: EC:1.16.1.1 +xref: KEGG_REACTION:R02807 +xref: MetaCyc:MERCURY-II-REDUCTASE-RXN +xref: RHEA:23856 +xref: UM-BBD_reactionID:r0406 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0016153 +name: urocanate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O." [EC:4.2.1.49, RHEA:13101] +synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)" EXACT [EC:4.2.1.49] +synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity" EXACT [EC:4.2.1.49] +synonym: "imidazolonepropionate hydrolase activity" EXACT [EC:4.2.1.49] +synonym: "urocanase activity" EXACT [EC:4.2.1.49] +xref: EC:4.2.1.49 +xref: KEGG_REACTION:R02914 +xref: MetaCyc:UROCANATE-HYDRATASE-RXN +xref: Reactome:R-HSA-70903 "urocanate + H2O => 4-imidazolone-5-propionate" +xref: RHEA:13101 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0016154 +name: pyrimidine-nucleoside phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate." [EC:2.4.2.2] +synonym: "Py-NPase activity" EXACT [EC:2.4.2.2] +synonym: "pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.2] +xref: EC:2.4.2.2 +xref: MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0016155 +name: formyltetrahydrofolate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH." [EC:1.5.1.6, RHEA:10180] +synonym: "10-formyl tetrahydrofolate:NADP oxidoreductase activity" EXACT [EC:1.5.1.6] +synonym: "10-formyl-H2PtGlu:NADP oxidoreductase activity" EXACT [EC:1.5.1.6] +synonym: "10-formyl-H4folate dehydrogenase activity" EXACT [EC:1.5.1.6] +synonym: "10-formyltetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.6] +synonym: "10-formyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.6] +synonym: "N10-formyltetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.6] +xref: EC:1.5.1.6 +xref: KEGG_REACTION:R00941 +xref: MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN +xref: RHEA:10180 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016156 +name: fumarate reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH." [EC:1.3.1.6, RHEA:18281] +synonym: "NADH-dependent fumarate reductase activity" EXACT [EC:1.3.1.6] +synonym: "NADH-fumarate reductase activity" EXACT [EC:1.3.1.6] +synonym: "succinate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.6] +xref: EC:1.3.1.6 +xref: KEGG_REACTION:R00402 +xref: MetaCyc:FUMARATE-REDUCTASE-NADH-RXN +xref: RHEA:18281 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016157 +name: sucrose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose." [EC:2.4.1.13] +synonym: "NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.13] +synonym: "sucrose synthetase activity" EXACT [EC:2.4.1.13] +synonym: "sucrose-UDP glucosyltransferase activity" EXACT [EC:2.4.1.13] +synonym: "sucrose-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.13] +synonym: "UDP-glucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] +synonym: "UDPglucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] +synonym: "uridine diphosphoglucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] +xref: EC:2.4.1.13 +xref: MetaCyc:SUCROSE-SYNTHASE-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0016158 +name: 3-phytase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate." [EC:3.1.3.8] +synonym: "1-phytase activity" EXACT [EC:3.1.3.8] +synonym: "myo-inositol-hexakisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.8] +synonym: "myo-inositol-hexaphosphate 3-phosphohydrolase activity" EXACT [] +synonym: "phytase activity" BROAD [] +synonym: "phytate 1-phosphatase activity" EXACT [EC:3.1.3.8] +synonym: "phytate 3-phosphatase activity" EXACT [] +xref: EC:3.1.3.8 +xref: MetaCyc:RXN0-1001 +xref: RHEA:16989 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0016159 +name: muconolactone delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate." [EC:5.3.3.4] +synonym: "5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity" EXACT [EC:5.3.3.4] +synonym: "muconolactone D-isomerase activity" EXACT [] +synonym: "muconolactone isomerase activity" EXACT [EC:5.3.3.4] +xref: EC:5.3.3.4 +xref: MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN +xref: RHEA:12348 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0016160 +name: amylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of amylose or an amylose derivative." [GOC:ai] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0016161 +name: beta-amylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains." [EC:3.2.1.2] +synonym: "1,4-alpha-D-glucan maltohydrolase activity" EXACT [EC:3.2.1.2] +synonym: "beta amylase activity" EXACT [EC:3.2.1.2] +synonym: "glycogenase activity" BROAD [EC:3.2.1.2] +synonym: "saccharogen amylase activity" EXACT [EC:3.2.1.2] +xref: EC:3.2.1.2 +xref: MetaCyc:RXN-12279 +xref: MetaCyc:RXN-1827 +is_a: GO:0016160 ! amylase activity + +[Term] +id: GO:0016162 +name: cellulose 1,4-beta-cellobiosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains." [EC:3.2.1.91] +synonym: "1,4-beta-cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "1,4-beta-D-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "1,4-beta-glucan cellobiosidase activity" EXACT [EC:3.2.1.91] +synonym: "avicelase activity" BROAD [EC:3.2.1.91] +synonym: "beta-1,4-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "beta-1,4-glucan cellobiosylhydrolase activity" EXACT [EC:3.2.1.91] +synonym: "C1 cellulase activity" EXACT [EC:3.2.1.91] +synonym: "CBH 1" RELATED [EC:3.2.1.91] +synonym: "cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "cellobiohydrolase I" RELATED [EC:3.2.1.91] +synonym: "cellobiosidase activity" EXACT [EC:3.2.1.91] +synonym: "exo-1,4-beta-D-glucanase activity" EXACT [EC:3.2.1.91] +synonym: "exo-beta-1,4-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "exo-cellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "exocellobiohydrolase activity" EXACT [EC:3.2.1.91] +synonym: "exoglucanase activity" EXACT [EC:3.2.1.91] +xref: EC:3.2.1.91 +xref: MetaCyc:3.2.1.91-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0016163 +name: nitrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate." [EC:1.18.6.1] +synonym: "iron-iron nitrogenase activity" NARROW [] +synonym: "molybdenum-iron nitrogenase activity" NARROW [] +synonym: "reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity" EXACT [EC:1.18.6.1] +synonym: "vanadium-iron nitrogenase activity" NARROW [] +xref: EC:1.18.6.1 +xref: MetaCyc:NITROGENASE-RXN +xref: UM-BBD_enzymeID:e0395 +is_a: GO:0016732 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor + +[Term] +id: GO:0016164 +name: obsolete Mo-molybdopterin oxidoreductase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the differentia from the parent is a gene product feature (specifically, the presence of a molybdopterin cofactor in the protein). It has also never been defined. +synonym: "Mo-molybdopterin oxidoreductase activity" EXACT [] +synonym: "molybdopterin oxidoreductase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016491 + +[Term] +id: GO:0016165 +name: linoleate 13S-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate." [EC:1.13.11.12, GOC:lb] +synonym: "carotene oxidase activity" NARROW [EC:1.13.11.12] +synonym: "fat oxidase activity" EXACT [EC:1.13.11.12] +synonym: "linoleate:oxygen 13-oxidoreductase activity" EXACT [EC:1.13.11.12] +synonym: "lionoleate:O2 oxidoreductase activity" EXACT [EC:1.13.11.12] +synonym: "lipoperoxidase activity" EXACT [EC:1.13.11.12] +synonym: "lipoxidase activity" EXACT [EC:1.13.11.12] +synonym: "lipoxydase activity" EXACT [EC:1.13.11.12] +synonym: "lipoxygenase activity" BROAD [] +xref: EC:1.13.11.12 +xref: MetaCyc:LIPOXYGENASE-RXN +xref: RHEA:22780 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0016166 +name: phytoene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene." [PMID:29176862] +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016167 +name: glial cell-derived neurotrophic factor receptor activity +namespace: molecular_function +def: "Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling] +synonym: "GDNF receptor activity" EXACT [GOC:mah] +synonym: "glial cell line-derived neurotrophic factor receptor activity" EXACT [GOC:bf] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0035860 ! glial cell-derived neurotrophic factor receptor signaling pathway + +[Term] +id: GO:0016168 +name: chlorophyll binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment." [GOC:jl] +is_a: GO:0043168 ! anion binding +is_a: GO:0046906 ! tetrapyrrole binding +is_a: GO:0048037 ! cofactor binding +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0016169 +name: bacteriochlorophyll c binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria." [ISBN:0192800981] +is_a: GO:0042314 ! bacteriochlorophyll binding + +[Term] +id: GO:0016170 +name: interleukin-15 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-15 receptor." [GOC:ai] +synonym: "IL-15" NARROW [] +synonym: "interleukin-15 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0016171 +name: obsolete cell surface antigen +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "cell surface antigen" EXACT [] +is_obsolete: true + +[Term] +id: GO:0016172 +name: obsolete antifreeze activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures." [GOC:jl] +comment: This term was made obsolete because it refers to a biological process. +synonym: "antifreeze activity" EXACT [] +is_obsolete: true +consider: GO:0042309 +consider: GO:0050825 +consider: GO:0050826 + +[Term] +id: GO:0016173 +name: obsolete ice nucleation inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the formation of ice crystals." [GOC:ai] +comment: This term was made obsolete because it refers to a biological process. +synonym: "ice nucleation inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0042309 +consider: GO:0050825 +consider: GO:0050826 + +[Term] +id: GO:0016174 +name: NAD(P)H oxidase (H(2)O(2)-forming activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide." [EC:1.6.3.1, PMID:10401672, PMID:10601291, PMID:11822874, RHEA:11260] +synonym: "dual oxidase activity" RELATED [EC:1.6.3.1] +synonym: "NAD(P)H oxidase activity" BROAD [] +synonym: "NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.6.3.1] +synonym: "NADPH oxidase" BROAD [EC:1.6.3.1] +synonym: "p138tox" RELATED [EC:1.6.3.1] +synonym: "ThOX activity" NARROW [EC:1.6.3.1] +synonym: "THOX2 activity" NARROW [EC:1.6.3.1] +synonym: "thyroid NADPH oxidase activity" NARROW [] +synonym: "thyroid oxidase 2 activity" NARROW [EC:1.6.3.1] +synonym: "thyroid oxidase activity" NARROW [EC:1.6.3.1] +xref: EC:1.6.3.1 +xref: Reactome:R-HSA-5693681 "DUOX1,2 reduce O2 to H2O2" +xref: RHEA:11260 +is_a: GO:0050664 ! oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor + +[Term] +id: GO:0016175 +name: superoxide-generating NADPH oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-." [GOC:ai, PMID:10806195] +synonym: "cytochrome B-245" RELATED [] +xref: EC:1.6.3 +xref: Reactome:R-HSA-1222376 "NOX2 generates superoxide from oxygen" +xref: Reactome:R-HSA-1236967 "Alkalization of the phagosomal lumen by NOX2" +xref: Reactome:R-HSA-1497810 "Uncoupled eNOS favours the formation of superoxide" +xref: Reactome:R-HSA-5218841 "NADPH oxidase 2 generates superoxide from oxygen" +xref: Reactome:R-HSA-5668629 "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP" +xref: Reactome:R-HSA-5668718 "NOX1 complex:RAC1:GTP generates superoxide from oxygen" +xref: Reactome:R-HSA-5668731 "NOX3 complex:RAC1:GTP generates superoxide from oxygen" +xref: Reactome:R-HSA-6789092 "NOX2 generates superoxide anion from oxygen" +xref: Reactome:R-HSA-6807557 "NOX4, NOX5 reduce O2 to O2.-" +is_a: GO:0050664 ! oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor + +[Term] +id: GO:0016176 +name: superoxide-generating NADPH oxidase activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme superoxide-generating NADPH oxidase." [GOC:ai] +synonym: "neutrophil cytosol factor 2" NARROW [] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0016175 ! superoxide-generating NADPH oxidase activity + +[Term] +id: GO:0016180 +name: snRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule." [GOC:jl] +is_a: GO:0016073 ! snRNA metabolic process +is_a: GO:0034470 ! ncRNA processing + +[Term] +id: GO:0016182 +name: synaptic vesicle budding from endosome +namespace: biological_process +def: "Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes." [GOC:curators, PMID:10099709, PMID:24596248] +subset: goslim_synapse +synonym: "endosome to synaptic vesicle budding" RELATED [GOC:mah] +synonym: "synaptic vesicle budding involved in synaptic vesicle exocytosis" EXACT [GOC:mah] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0070142 ! synaptic vesicle budding +is_a: GO:0099003 ! vesicle-mediated transport in synapse +relationship: part_of GO:0036466 ! synaptic vesicle recycling via endosome + +[Term] +id: GO:0016183 +name: synaptic vesicle coating +namespace: biological_process +def: "The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles." [GOC:curators, PMID:10099709, PMID:20448150] +subset: goslim_synapse +is_a: GO:0006901 ! vesicle coating +relationship: part_of GO:0016185 ! synaptic vesicle budding from presynaptic endocytic zone membrane + +[Term] +id: GO:0016184 +name: obsolete synaptic vesicle retrieval +namespace: biological_process +def: "OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane." [GOC:curators] +comment: This term was made obsolete because it was wrongly defined. +synonym: "synaptic vesicle retrieval" EXACT [] +is_obsolete: true +consider: GO:0016192 + +[Term] +id: GO:0016185 +name: synaptic vesicle budding from presynaptic endocytic zone membrane +namespace: biological_process +def: "Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle." [GOC:curators, PMID:10099709, PMID:20448150] +subset: goslim_synapse +synonym: "synaptic vesicle budding from pre-synaptic membrane" EXACT [] +synonym: "synaptic vesicle budding involved in synaptic vesicle endocytosis" EXACT [GOC:mah] +is_a: GO:0070142 ! synaptic vesicle budding +intersection_of: GO:0070142 ! synaptic vesicle budding +intersection_of: part_of GO:0048488 ! synaptic vesicle endocytosis +relationship: part_of GO:0048488 ! synaptic vesicle endocytosis + +[Term] +id: GO:0016186 +name: obsolete synaptic vesicle fission +namespace: biological_process +def: "OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane." [GOC:curators] +comment: This term was made obsolete because it was wrongly defined. +synonym: "synaptic vesicle fission" EXACT [] +is_obsolete: true +consider: GO:0016192 + +[Term] +id: GO:0016187 +name: obsolete synaptic vesicle internalization +namespace: biological_process +def: "OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis." [GOC:curators] +comment: This term was made obsolete because it was wrongly defined. +synonym: "synaptic vesicle internalization" EXACT [] +is_obsolete: true +consider: GO:0016192 + +[Term] +id: GO:0016188 +name: synaptic vesicle maturation +namespace: biological_process +def: "Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle." [GOC:curators, PMID:10099709] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0021700 ! developmental maturation + +[Term] +id: GO:0016189 +name: synaptic vesicle to endosome fusion +namespace: biological_process +def: "Fusion of a synaptic vesicle with an endosome." [GOC:curators, PMID:10099709] +comment: This covers fusion of synaptic vesicles trafficked to the synapse as well as fusion of endocytosed vesicles as part of recycling. It is there for not part of the synaptic vesicle cycle. +subset: goslim_synapse +is_a: GO:0048284 ! organelle fusion +relationship: part_of GO:0099532 ! synaptic vesicle endosomal processing + +[Term] +id: GO:0016191 +name: synaptic vesicle uncoating +namespace: biological_process +def: "The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane." [GOC:curators, PMID:10099709, PMID:24596248] +subset: goslim_synapse +synonym: "synaptic vesicle coat depolymerization" EXACT [] +synonym: "synaptic vesicle coat protein depolymerization" EXACT [] +is_a: GO:0072318 ! clathrin coat disassembly +relationship: part_of GO:0048488 ! synaptic vesicle endocytosis + +[Term] +id: GO:0016192 +name: vesicle-mediated transport +namespace: biological_process +alt_id: GO:0006899 +def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +synonym: "nonselective vesicle transport" NARROW [] +synonym: "protein sorting along secretory pathway" RELATED [] +synonym: "vesicle trafficking" RELATED [] +synonym: "vesicle transport" EXACT [] +synonym: "vesicular transport" EXACT [GOC:mah] +is_a: GO:0006810 ! transport +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0016197 +name: endosomal transport +namespace: biological_process +alt_id: GO:0032439 +def: "The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane." [ISBN:0198506732] +subset: goslim_yeast +synonym: "endosome localisation" EXACT [GOC:mah] +synonym: "endosome localization" RELATED [] +synonym: "endosome transport" RELATED [GOC:bf] +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0016198 +name: axon choice point recognition +namespace: biological_process +def: "The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth." [PMID:10218152] +is_a: GO:0008038 ! neuron recognition +relationship: part_of GO:0007411 ! axon guidance + +[Term] +id: GO:0016199 +name: axon midline choice point recognition +namespace: biological_process +def: "The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline." [PMID:11376484] +is_a: GO:0016198 ! axon choice point recognition + +[Term] +id: GO:0016200 +name: synaptic target attraction +namespace: biological_process +def: "The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets." [GOC:mah, ISBN:0878932437] +is_a: GO:0050918 ! positive chemotaxis +relationship: part_of GO:0008039 ! synaptic target recognition + +[Term] +id: GO:0016201 +name: synaptic target inhibition +namespace: biological_process +def: "The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source." [GOC:mah, ISBN:0878932437] +is_a: GO:0050919 ! negative chemotaxis +relationship: part_of GO:0008039 ! synaptic target recognition + +[Term] +id: GO:0016202 +name: regulation of striated muscle tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators] +is_a: GO:0048634 ! regulation of muscle organ development +is_a: GO:1901861 ! regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014706 ! striated muscle tissue development +relationship: regulates GO:0014706 ! striated muscle tissue development + +[Term] +id: GO:0016203 +name: muscle attachment +namespace: biological_process +def: "The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)." [GOC:isa_complete, GOC:sart] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0060538 ! skeletal muscle organ development + +[Term] +id: GO:0016204 +name: determination of muscle attachment site +namespace: biological_process +def: "The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site." [GOC:isa_complete] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0016203 ! muscle attachment + +[Term] +id: GO:0016205 +name: selenocysteine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine." [EC:2.1.1.280, PMID:10026151] +xref: EC:2.1.1.280 +xref: MetaCyc:RXN-11061 +xref: RHEA:26341 +is_a: GO:0051995 ! Se-methyltransferase activity + +[Term] +id: GO:0016206 +name: catechol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol." [EC:2.1.1.6] +synonym: "catechol methyltransferase activity" EXACT [EC:2.1.1.6] +synonym: "catecholamine O-methyltransferase activity" EXACT [EC:2.1.1.6] +synonym: "COMT I" RELATED [EC:2.1.1.6] +synonym: "COMT II" RELATED [EC:2.1.1.6] +synonym: "MB-COMT (membrane-bound form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6] +synonym: "S-adenosyl-L-methionine:catechol O-methyltransferase activity" EXACT [EC:2.1.1.6] +synonym: "S-COMT (soluble form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6] +xref: EC:2.1.1.6 +xref: MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-175983 "COMT transfer CH3 from AdoMet to 3,4DHBNZ" +xref: Reactome:R-HSA-8955010 "LRTOMT transfers methyl group from AdoMet to DA, forming 3MT" +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0016207 +name: 4-coumarate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA." [EC:6.2.1.12] +synonym: "4-coumarate-CoA synthetase activity" EXACT [] +synonym: "4-coumarate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.12] +synonym: "4-coumarate:CoA ligase activity" EXACT [] +synonym: "4-coumarate:coenzyme A ligase activity" EXACT [EC:6.2.1.12] +synonym: "4-coumaroyl-CoA synthase activity" EXACT [EC:6.2.1.12] +synonym: "4-coumaroyl-CoA synthetase activity" EXACT [EC:6.2.1.12] +synonym: "4-coumaryl-CoA synthetase activity" EXACT [EC:6.2.1.12] +synonym: "4CL" RELATED [EC:6.2.1.12] +synonym: "caffeolyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] +synonym: "feruloyl CoA ligase activity" EXACT [EC:6.2.1.12] +synonym: "feruloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] +synonym: "hydroxycinnamate:CoA ligase activity" EXACT [EC:6.2.1.12] +synonym: "hydroxycinnamoyl CoA synthetase activity" EXACT [EC:6.2.1.12] +synonym: "p-coumaroyl CoA ligase activity" EXACT [EC:6.2.1.12] +synonym: "p-coumaryl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] +synonym: "p-coumaryl-CoA ligase activity" EXACT [EC:6.2.1.12] +synonym: "p-coumaryl-CoA synthetase activity" EXACT [EC:6.2.1.12] +synonym: "p-hydroxycinnamic acid:CoA ligase activity" EXACT [EC:6.2.1.12] +synonym: "p-hydroxycinnamoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] +synonym: "sinapoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] +xref: EC:6.2.1.12 +xref: KEGG_REACTION:R01616 +xref: MetaCyc:4-COUMARATE--COA-LIGASE-RXN +xref: RHEA:19641 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0016208 +name: AMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with AMP, adenosine monophosphate." [GOC:go_curators] +is_a: GO:0008144 ! drug binding +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0016209 +name: antioxidant activity +namespace: molecular_function +def: "Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage." [ISBN:0198506732] +subset: goslim_metagenomics +subset: goslim_pir +is_a: GO:0003674 ! molecular_function +intersection_of: GO:0003674 ! molecular_function +intersection_of: part_of GO:0098869 ! cellular oxidant detoxification +relationship: part_of GO:0098869 ! cellular oxidant detoxification + +[Term] +id: GO:0016210 +name: naringenin-chalcone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2." [EC:2.3.1.74] +synonym: "DOCS" NARROW [] +synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)" BROAD [EC:2.3.1.74] +xref: EC:2.3.1.74 +xref: MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN +xref: RHEA:11128 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016211 +name: ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] +xref: EC:6.3.1 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0016212 +name: kynurenine-oxoglutarate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate." [EC:2.6.1.7] +synonym: "kynurenine 2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.7] +synonym: "kynurenine aminotransferase activity" BROAD [EC:2.6.1.7] +synonym: "kynurenine transaminase (cyclizing)" EXACT [EC:2.6.1.7] +synonym: "kynurenine--oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.7] +synonym: "kynurenine-oxoglutarate aminotransferase activity" EXACT [] +synonym: "L-kynurenine aminotransferase activity" EXACT [EC:2.6.1.7] +synonym: "L-kynurenine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.7] +xref: EC:2.6.1.7 +xref: MetaCyc:2.6.1.7-RXN +xref: Reactome:R-HSA-893583 "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate" +xref: Reactome:R-HSA-893596 "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu" +xref: Reactome:R-HSA-901097 "kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2]" +xref: RHEA:20964 +is_a: GO:0036137 ! kynurenine aminotransferase activity + +[Term] +id: GO:0016213 +name: linoleoyl-CoA desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O." [RHEA:22196] +comment: Note that this function was formerly EC:1.14.99.25. +synonym: "delta(6)-acyl CoA desaturase activity" BROAD [] +synonym: "delta(6)-desaturase activity" BROAD [] +synonym: "delta(6)-fatty acyl-CoA desaturase activity" BROAD [] +synonym: "delta6-acyl CoA desaturase activity" EXACT [EC:1.14.19.3] +synonym: "delta6-desaturase activity" EXACT [EC:1.14.19.3] +synonym: "delta6-fatty acyl-CoA desaturase activity" EXACT [EC:1.14.19.3] +synonym: "fatty acid 6-desaturase activity" BROAD [] +synonym: "fatty acid delta(6)-desaturase activity" BROAD [] +synonym: "fatty acid delta6-desaturase activity" EXACT [EC:1.14.19.3] +synonym: "linoleate desaturase activity" RELATED [] +synonym: "linoleic acid desaturase activity" RELATED [] +synonym: "linoleic desaturase activity" RELATED [] +synonym: "linoleoyl CoA desaturase activity" EXACT [] +synonym: "linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.3] +synonym: "linoleoyl-coenzyme A desaturase activity" EXACT [] +synonym: "long-chain fatty acid delta(6)-desaturase activity" BROAD [] +synonym: "long-chain fatty acid delta6-desaturase activity" EXACT [EC:1.14.19.3] +xref: EC:1.14.19.3 +xref: MetaCyc:1.14.19.3-RXN +xref: Reactome:R-HSA-2046084 "Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA" +xref: Reactome:R-HSA-2046096 "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA" +xref: Reactome:R-HSA-2046097 "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA" +xref: Reactome:R-HSA-2046099 "Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA" +xref: RHEA:22196 +is_a: GO:0016215 ! acyl-CoA desaturase activity + +[Term] +id: GO:0016215 +name: acyl-CoA desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O." [EC:1.14.19.1, EC:1.14.19.5, GOC:mah] +synonym: "CoA desaturase activity" BROAD [] +xref: EC:1.14.19 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0016216 +name: isopenicillin-N synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N." [EC:1.21.3.1, RHEA:22428] +synonym: "isopenicillin N synthase activity" EXACT [EC:1.21.3.1] +synonym: "isopenicillin-N synthetase activity" EXACT [] +synonym: "N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.21.3.1] +xref: EC:1.21.3.1 +xref: KEGG_REACTION:R04872 +xref: MetaCyc:1.21.3.1-RXN +xref: RHEA:22428 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0016217 +name: N-ethylammeline chlorohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+." [MetaCyc:R465-RXN] +xref: MetaCyc:R465-RXN +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0016218 +name: obsolete polyketide synthase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:curators] +comment: This term was made obsolete because the activity it describes does not exist, and the gene product with the name 'polyketide synthase' has multiple functional domains, so using the name to describe a single function would be misleading. +synonym: "polyketide synthase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030639 +consider: GO:0034081 + +[Term] +id: GO:0016222 +name: procollagen-proline 4-dioxygenase complex +namespace: cellular_component +def: "A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase." [PMID:14500733, PMID:7753822] +synonym: "procollagen-proline, 2-oxoglutarate-4-dioxygenase complex" EXACT [EC:1.14.11.2] +synonym: "prolyl 4-hydroxylase complex" BROAD [EC:1.14.11.2] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0016223 +name: beta-alanine-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine." [EC:2.6.1.18] +synonym: "beta-alanine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.18] +synonym: "beta-alanine-alpha-alanine transaminase activity" EXACT [EC:2.6.1.18] +synonym: "beta-alanine-pyruvate aminotransferase activity" EXACT [] +synonym: "L-alanine:3-oxopropanoate aminotransferase activity" EXACT [EC:2.6.1.18] +synonym: "omega-amino acid--pyruvate aminotransferase activity" EXACT [EC:2.6.1.18] +xref: EC:2.6.1.18 +xref: MetaCyc:2.6.1.18-RXN +xref: Reactome:R-HSA-909776 "beta-alanine + pyruvate => 3-oxopropanoate + alanine" +xref: RHEA:14077 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0016226 +name: iron-sulfur cluster assembly +namespace: biological_process +def: "The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster." [GOC:jl, GOC:mah, GOC:pde, GOC:vw] +subset: goslim_metagenomics +synonym: "iron-sulfur cluster biosynthesis" RELATED [] +synonym: "iron-sulphur cluster assembly" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0031163 ! metallo-sulfur cluster assembly +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0016227 +name: obsolete tRNA sulfurtransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide." [EC:2.8.1.4] +comment: This term was made obsolete because tRNA thionucleotide formation is a multistep process; there is no single reaction in which cysteine reacts with an activated tRNA directly +synonym: "L-cysteine:tRNA sulfurtransferase activity" EXACT [EC:2.8.1.4] +synonym: "ribonucleate sulfurtransferase activity" EXACT [EC:2.8.1.4] +synonym: "RNA sulfurtransferase activity" EXACT [EC:2.8.1.4] +synonym: "transfer ribonucleate sulfurtransferase activity" EXACT [EC:2.8.1.4] +synonym: "transfer RNA sulfurtransferase activity" EXACT [EC:2.8.1.4] +synonym: "transfer RNA thiolase activity" EXACT [EC:2.8.1.4] +synonym: "tRNA sulfurtransferase activity" EXACT [] +synonym: "tRNA sulphurtransferase activity" EXACT [] +xref: EC:2.8.1.4 +xref: MetaCyc:TRNA-S-TRANSFERASE-RXN +is_obsolete: true +replaced_by: GO:0034227 +consider: GO:0016783 + +[Term] +id: GO:0016229 +name: steroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative." [GOC:mah] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016230 +name: sphingomyelin phosphodiesterase activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme sphingomyelin phosphodiesterase." [GOC:ai] +synonym: "neutral sphingomyelinase activator" EXACT [] +is_a: GO:0016004 ! phospholipase activator activity +relationship: positively_regulates GO:0004767 ! sphingomyelin phosphodiesterase activity + +[Term] +id: GO:0016231 +name: beta-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides." [EC:3.2.1.52, MetaCyc:3.2.1.52-RXN] +is_a: GO:0004563 ! beta-N-acetylhexosaminidase activity + +[Term] +id: GO:0016232 +name: HNK-1 sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R)." [PMID:9478973] +synonym: "HNK-1 sulphotransferase activity" EXACT [] +xref: Reactome:R-HSA-6786048 "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0016233 +name: telomere capping +namespace: biological_process +def: "A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins." [GOC:mah, GOC:rn, PMID:11349150, PMID:11352055] +synonym: "telomere end protection" EXACT [] +is_a: GO:0000723 ! telomere maintenance + +[Term] +id: GO:0016234 +name: inclusion body +namespace: cellular_component +def: "A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers." [GOC:mah, PMID:11121744] +synonym: "cellular inclusion" RELATED [NIF_Subcellular:sao120573470] +synonym: "neuronal cytoplasmic inclusion" NARROW [] +xref: NIF_Subcellular:sao120573470 +xref: Wikipedia:Inclusion_bodies +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0016235 +name: aggresome +namespace: cellular_component +def: "An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules." [PMID:11121744] +xref: Wikipedia:Aggresome +is_a: GO:0016234 ! inclusion body + +[Term] +id: GO:0016236 +name: macroautophagy +namespace: biological_process +alt_id: GO:0034262 +def: "The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded." [PMID:11099404, PMID:12914914, PMID:15798367, PMID:16973210, PMID:20159618, PMID:9412464] +comment: Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618). As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities. +synonym: "autophagy" BROAD [] +is_a: GO:0006914 ! autophagy + +[Term] +id: GO:0016237 +name: lysosomal microautophagy +namespace: biological_process +def: "The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment." [PMID:14679207, PMID:15798367, PMID:16973210, PMID:9566964] +is_a: GO:0006914 ! autophagy + +[Term] +id: GO:0016239 +name: positive regulation of macroautophagy +namespace: biological_process +def: "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation." [GOC:go_curators, PMID:9412464] +synonym: "activation of macroautophagy" NARROW [] +synonym: "positive regulation of starvation-induced autophagy" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "stimulation of macroautophagy" NARROW [] +synonym: "up regulation of macroautophagy" EXACT [] +synonym: "up-regulation of macroautophagy" EXACT [] +synonym: "upregulation of macroautophagy" EXACT [] +is_a: GO:0010508 ! positive regulation of autophagy +is_a: GO:0016241 ! regulation of macroautophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016236 ! macroautophagy +relationship: positively_regulates GO:0016236 ! macroautophagy + +[Term] +id: GO:0016240 +name: autophagosome membrane docking +namespace: biological_process +def: "The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere." [GOC:autophagy, GOC:mah] +synonym: "autophagic vacuole docking" EXACT [GOC:autophagy] +is_a: GO:0140056 ! organelle localization by membrane tethering +intersection_of: GO:0140056 ! organelle localization by membrane tethering +intersection_of: part_of GO:0097352 ! autophagosome maturation +relationship: part_of GO:0097352 ! autophagosome maturation + +[Term] +id: GO:0016241 +name: regulation of macroautophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macroautophagy." [GOC:krc] +synonym: "regulation of starvation-induced autophagy" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010506 ! regulation of autophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016236 ! macroautophagy +relationship: regulates GO:0016236 ! macroautophagy + +[Term] +id: GO:0016242 +name: negative regulation of macroautophagy +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy." [GOC:go_curators] +synonym: "down regulation of macroautophagy" EXACT [] +synonym: "down-regulation of macroautophagy" EXACT [] +synonym: "downregulation of macroautophagy" EXACT [] +synonym: "inhibition of macroautophagy" NARROW [] +synonym: "negative regulation of starvation-induced autophagy" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010507 ! negative regulation of autophagy +is_a: GO:0016241 ! regulation of macroautophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016236 ! macroautophagy +relationship: negatively_regulates GO:0016236 ! macroautophagy + +[Term] +id: GO:0016243 +name: regulation of autophagosome size +namespace: biological_process +def: "Any process that modulates the size of the autophagosome." [GOC:autophagy, GOC:krc] +synonym: "regulation of autophagic vacuole size" EXACT [GOC:autophagy] +is_a: GO:0032535 ! regulation of cellular component size +is_a: GO:1905037 ! autophagosome organization + +[Term] +id: GO:0016246 +name: RNA interference +namespace: biological_process +def: "The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes." [GOC:ems, PMID:11201747, PMID:11713190, PMID:18771919] +comment: Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'. +synonym: "posttranscriptional gene silencing by siRNA" EXACT [GOC:mah] +synonym: "RNAi" EXACT [] +xref: Wikipedia:RNA_interference +is_a: GO:0035194 ! post-transcriptional gene silencing by RNA +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0016247 +name: channel regulator activity +namespace: molecular_function +def: "Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel." [GOC:mah] +is_a: GO:0098772 ! molecular function regulator + +[Term] +id: GO:0016248 +name: channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of a channel via direct interaction with the channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel." [GOC:mah] +is_a: GO:0016247 ! channel regulator activity +relationship: negatively_regulates GO:0015267 ! channel activity + +[Term] +id: GO:0016250 +name: N-sulfoglucosamine sulfohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate." [EC:3.10.1.1] +synonym: "2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)" EXACT [EC:3.10.1.1] +synonym: "heparin sulfamidase activity" EXACT [EC:3.10.1.1] +synonym: "N-sulfo-D-glucosamine sulfohydrolase activity" EXACT [EC:3.10.1.1] +synonym: "N-sulphoglucosamine sulphohydrolase activity" EXACT [] +synonym: "sulfoglucosamine sulfamidase activity" EXACT [EC:3.10.1.1] +synonym: "sulphamidase activity" EXACT [EC:3.10.1.1] +xref: EC:3.10.1.1 +xref: MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN +xref: Reactome:R-HSA-1678708 "SGSH hydrolyses Heparan sulfate chain(2)" +xref: Reactome:R-HSA-2090043 "SGSH hydrolyses Heparan sulfate chain(7)" +xref: Reactome:R-HSA-2263444 "Defective SGSH does not hydrolyse Heparan sulfate chain(7)" +xref: Reactome:R-HSA-9036050 "Defective SGSH does not hydrolyse Heparan sulfate chain(2)" +xref: RHEA:17881 +is_a: GO:0016826 ! hydrolase activity, acting on acid sulfur-nitrogen bonds + +[Term] +id: GO:0016251 +name: RNA polymerase II general transcription initiation factor activity +namespace: molecular_function +alt_id: GO:0000983 +alt_id: GO:0001075 +alt_id: GO:0003703 +def: "An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP)." [GOC:txnOH-2018, PMID:10384286, PMID:25693126] +comment: General transcription factors assemble with the RNA polymerase at promoter DNA to form the pre-initiation complex (PIC), bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present in all promoters to initiate transcription. The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors belong to the constitutive machinery required for transcription to occur. +synonym: "basal RNA polymerase II transcription factor activity" EXACT [] +synonym: "general RNA polymerase II transcription factor activity" EXACT [] +synonym: "GTF2 activity" EXACT [] +synonym: "RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity" RELATED [] +synonym: "RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly" RELATED [] +synonym: "sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly" RELATED [] +synonym: "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly" RELATED [] +synonym: "transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding" RELATED [] +is_a: GO:0140223 ! general transcription initiation factor activity +relationship: part_of GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0016252 +name: obsolete nonspecific RNA polymerase II transcription factor activity +namespace: molecular_function +def: "OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set." [GOC:jl] +comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "nonspecific RNA polymerase II transcription factor activity" EXACT [] +is_obsolete: true +consider: GO:0006366 +consider: GO:0016251 + +[Term] +id: GO:0016254 +name: preassembly of GPI anchor in ER membrane +namespace: biological_process +def: "The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane." [ISBN:0879695595] +synonym: "preassembly of GPI anchor in endoplasmic reticulum membrane" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process +relationship: part_of GO:0006506 ! GPI anchor biosynthetic process + +[Term] +id: GO:0016255 +name: attachment of GPI anchor to protein +namespace: biological_process +def: "A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain." [ISBN:0879695595] +is_a: GO:0006464 ! cellular protein modification process +relationship: part_of GO:0006506 ! GPI anchor biosynthetic process + +[Term] +id: GO:0016256 +name: N-glycan processing to lysosome +namespace: biological_process +def: "The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome." [ISBN:0879695595] +is_a: GO:0006491 ! N-glycan processing +intersection_of: GO:0006491 ! N-glycan processing +intersection_of: part_of GO:0006622 ! protein targeting to lysosome +relationship: part_of GO:0006622 ! protein targeting to lysosome + +[Term] +id: GO:0016257 +name: N-glycan processing to secreted and cell-surface N-glycans +namespace: biological_process +def: "The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus." [ISBN:0879695595] +is_a: GO:0006491 ! N-glycan processing + +[Term] +id: GO:0016258 +name: N-glycan diversification +namespace: biological_process +def: "The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases." [ISBN:0879695595] +is_a: GO:0006491 ! N-glycan processing + +[Term] +id: GO:0016259 +name: selenocysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins." [GOC:go_curators, ISBN:0198506732] +synonym: "selenocysteine metabolism" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process + +[Term] +id: GO:0016260 +name: selenocysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins." [GOC:go_curators, ISBN:0198506732] +synonym: "selenocysteine anabolism" EXACT [] +synonym: "selenocysteine biosynthesis" EXACT [] +synonym: "selenocysteine formation" EXACT [] +synonym: "selenocysteine synthesis" EXACT [] +is_a: GO:0009070 ! serine family amino acid biosynthetic process +is_a: GO:0016259 ! selenocysteine metabolic process + +[Term] +id: GO:0016261 +name: selenocysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins." [GOC:go_curators, ISBN:0198506732] +synonym: "selenocysteine breakdown" EXACT [] +synonym: "selenocysteine catabolism" EXACT [] +synonym: "selenocysteine degradation" EXACT [] +is_a: GO:0009071 ! serine family amino acid catabolic process +is_a: GO:0016259 ! selenocysteine metabolic process + +[Term] +id: GO:0016262 +name: protein N-acetylglucosaminyltransferase activity +namespace: molecular_function +alt_id: GO:0016253 +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein." [EC:2.4.1.94] +synonym: "N-GlcNAc transferase activity" EXACT [EC:2.4.1.94] +synonym: "UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity" EXACT [] +synonym: "UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity" EXACT [] +xref: EC:2.4.1.94 +xref: MetaCyc:2.4.1.94-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0016263 +name: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan." [EC:2.4.1.122, GOC:ma] +synonym: "Core 1 GalT" RELATED [] +synonym: "UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.122] +synonym: "UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.122] +synonym: "uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity" EXACT [EC:2.4.1.122] +xref: EC:2.4.1.122 +xref: MetaCyc:2.4.1.122-RXN +xref: Reactome:R-HSA-1964505 "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)" +xref: Reactome:R-HSA-6785524 "Defective C1GALT1C1 does not bind C1GALT1" +is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0016264 +name: gap junction assembly +namespace: biological_process +def: "Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids." [GOC:jid, ISBN:0716731363] +is_a: GO:0007043 ! cell-cell junction assembly + +[Term] +id: GO:0016265 +name: obsolete death +namespace: biological_process +def: "OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism." [GOC:mah, GOC:mtg_apoptosis, ISBN:0877797099] +comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants. +xref: Wikipedia:Death +is_obsolete: true +consider: GO:0008219 +consider: GO:0012501 + +[Term] +id: GO:0016266 +name: O-glycan processing +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0006493 ! protein O-linked glycosylation + +[Term] +id: GO:0016267 +name: O-glycan processing, core 1 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0016268 +name: O-glycan processing, core 2 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0016269 +name: O-glycan processing, core 3 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0016270 +name: O-glycan processing, core 4 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0016271 +name: obsolete tissue death +namespace: biological_process +def: "OBSOLETE. A permanent cessation of all vital functions of a tissue." [GOC:dph, GOC:mtg_apoptosis] +comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants. +is_obsolete: true +consider: GO:0008219 +consider: GO:0012501 + +[Term] +id: GO:0016272 +name: prefoldin complex +namespace: cellular_component +def: "A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics." [GOC:jl, PMID:17384227, PMID:24068951, PMID:9630229] +synonym: "GIM complex" NARROW [] +xref: Wikipedia:Prefoldin +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0016273 +name: arginine N-methyltransferase activity +namespace: molecular_function +def: "Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue." [GOC:mah] +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0016274 +name: protein-arginine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine." [GOC:mah, PMID:12351636] +synonym: "PRMT activity" EXACT [] +xref: Reactome:R-HSA-191790 "Loading and methylation of Sm proteins onto SMN Complexes" +xref: Reactome:R-HSA-5205798 "PRMT1,PRMT6 methylate arginine-4 of histone H4" +xref: Reactome:R-HSA-5205820 "PRMT6 methylates arginine-4 of histone H2A (H2AR3)" +xref: Reactome:R-HSA-5205822 "CARM1 methylates arginine-18 (H3R17) of histone H3" +xref: Reactome:R-HSA-5205824 "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)" +xref: Reactome:R-HSA-5205867 "PRMT1 methylates arginine-12 of histone H2A (H2AR11)" +xref: Reactome:R-HSA-5218952 "PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2)" +xref: Reactome:R-HSA-5229010 "CARM1 methylates arginine-27 of histone H3 (H3R26)" +xref: Reactome:R-HSA-5229203 "PRMT6 methylates histone H2A arginine-30 (H2AR29)" +xref: Reactome:R-HSA-5661126 "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4" +xref: Reactome:R-HSA-8879123 "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2" +xref: Reactome:R-HSA-8934735 "PRMT1 arginine-methylates RUNX1" +is_a: GO:0008276 ! protein methyltransferase activity +is_a: GO:0016273 ! arginine N-methyltransferase activity +relationship: part_of GO:0035246 ! peptidyl-arginine N-methylation + +[Term] +id: GO:0016275 +name: [cytochrome c]-arginine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine." [EC:2.1.1.124, GOC:ma] +synonym: "cytochrome c-arginine N-methyltransferase activity" EXACT [EC:2.1.1.124] +synonym: "S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea" RELATED [EC:2.1.1.124] +synonym: "S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea" RELATED [EC:2.1.1.124] +xref: EC:2.1.1.124 +xref: MetaCyc:2.1.1.124-RXN +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity + +[Term] +id: GO:0016277 +name: [myelin basic protein]-arginine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine." [PMID:6177833] +synonym: "myelin basic protein methylase activity" EXACT [EC:2.1.1.126] +synonym: "myelin basic protein methylase I" RELATED [EC:2.1.1.126] +synonym: "myelin basic protein-arginine N-methyltransferase activity" EXACT [EC:2.1.1.126] +synonym: "protein methylase I activity" BROAD [EC:2.1.1.126] +synonym: "S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity" EXACT [EC:2.1.1.126] +synonym: "S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity" EXACT [EC:2.1.1.126] +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity + +[Term] +id: GO:0016278 +name: lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue." [GOC:mah] +xref: Reactome:R-HSA-3222237 "SMYD2 methylates TP53" +xref: Reactome:R-HSA-6805730 "SETD9 methylates TP53" +xref: Reactome:R-HSA-6805740 "SETD8 methylates TP53" +xref: Reactome:R-HSA-6805755 "EHMT1:EHMT2 dimethylates TP53" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0016279 +name: protein-lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate." [PMID:12054878] +xref: Reactome:R-HSA-212263 "PRC2 trimethylates histone H3 at lysine-27" +xref: Reactome:R-HSA-212269 "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3" +xref: Reactome:R-HSA-8865237 "SETD6 methylates RELA in the NFkB complex" +xref: Reactome:R-HSA-8931858 "ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB" +xref: Reactome:R-HSA-8931974 "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A" +xref: Reactome:R-HSA-8932221 "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8" +xref: Reactome:R-HSA-8932243 "EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2" +xref: Reactome:R-HSA-8932275 "METTL22 transfers 3xCH3 from 3xAdoMet to KIN" +xref: Reactome:R-HSA-8932276 "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP" +xref: Reactome:R-HSA-8932413 "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1" +is_a: GO:0008276 ! protein methyltransferase activity +is_a: GO:0016278 ! lysine N-methyltransferase activity +relationship: part_of GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0016281 +name: eukaryotic translation initiation factor 4F complex +namespace: cellular_component +def: "The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome." [GOC:hb, PMID:8449919] +synonym: "eIF-4F" EXACT [] +synonym: "eukaryotic translation initiation factor 4 complex" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0016282 +name: eukaryotic 43S preinitiation complex +namespace: cellular_component +def: "A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA." [GOC:hjd, PMID:15145049] +synonym: "eukaryotic 43S pre-initiation complex" EXACT [] +is_a: GO:0070993 ! translation preinitiation complex +relationship: has_part GO:0022627 ! cytosolic small ribosomal subunit + +[Term] +id: GO:0016284 +name: obsolete alanine aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide." [GOC:jl] +comment: This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined. +synonym: "alanine aminopeptidase activity" EXACT [] +xref: EC:3.4.11 +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0016285 +name: obsolete cytosol alanyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides." [EC:3.4.11.14] +comment: This term was made obsolete because it represents a gene product and refers to cellular component information. +synonym: "aminopolypeptidase activity" EXACT [EC:3.4.11.14] +synonym: "arylamidase activity" NARROW [EC:3.4.11.14] +synonym: "cytosol alanyl aminopeptidase activity" EXACT [] +synonym: "cytosol aminopeptidase III activity" NARROW [EC:3.4.11.14] +synonym: "human liver aminopeptidase" NARROW [EC:3.4.11.14] +synonym: "liver aminopeptidase activity" NARROW [EC:3.4.11.14] +synonym: "puromycin-sensitive aminopeptidase activity" NARROW [EC:3.4.11.14] +synonym: "soluble alanyl aminopeptidase activity" EXACT [EC:3.4.11.14] +synonym: "thiol-activated aminopeptidase activity" EXACT [EC:3.4.11.14] +xref: EC:3.4.11.14 +xref: MetaCyc:3.4.11.14-RXN +is_obsolete: true +consider: GO:0004177 +consider: GO:0008235 + +[Term] +id: GO:0016286 +name: small conductance calcium-activated potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, OMIM:602754] +synonym: "SK calcium-activated potassium channel activity" EXACT [] +synonym: "SK KCa channels" EXACT [] +synonym: "small conductance KCa channels" EXACT [] +is_a: GO:0015269 ! calcium-activated potassium channel activity + +[Term] +id: GO:0016287 +name: glycerone-phosphate O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA." [EC:2.3.1.42, RHEA:17657] +synonym: "acyl-CoA:glycerone-phosphate O-acyltransferase activity" EXACT [EC:2.3.1.42] +synonym: "dihydroxyacetone phosphate acyltransferase activity" EXACT [EC:2.3.1.42] +xref: EC:2.3.1.42 +xref: KEGG_REACTION:R01013 +xref: MetaCyc:2.3.1.42-RXN +xref: Reactome:R-HSA-1483002 "DHAP is converted to 1-acyl GO3P by GNPAT" +xref: Reactome:R-HSA-75879 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH" +xref: RHEA:17657 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0016289 +name: CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group." [GOC:ai] +xref: Reactome:R-HSA-193385 "Hydrolysis of choloyl-CoA to cholate and CoASH" +xref: Reactome:R-HSA-6809354 "NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT" +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0016290 +name: palmitoyl-CoA hydrolase activity +namespace: molecular_function +alt_id: GO:0016293 +def: "Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate." [EC:3.1.2.2] +subset: goslim_chembl +synonym: "fatty acyl thioesterase I" RELATED [EC:3.1.2.2] +synonym: "long-chain fatty-acyl-CoA hydrolase activity" BROAD [] +synonym: "palmitoyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.2] +synonym: "palmitoyl thioesterase activity" EXACT [EC:3.1.2.2] +synonym: "palmitoyl-CoA deacylase activity" EXACT [EC:3.1.2.2] +synonym: "palmityl thioesterase activity" EXACT [EC:3.1.2.2] +synonym: "palmityl thioesterase I" RELATED [EC:3.1.2.2] +synonym: "palmityl-CoA deacylase activity" EXACT [EC:3.1.2.2] +xref: EC:3.1.2.2 +xref: MetaCyc:PALMITOYL-COA-HYDROLASE-RXN +xref: MetaCyc:PWY-5148 +xref: RHEA:16645 +is_a: GO:0047617 ! acyl-CoA hydrolase activity + +[Term] +id: GO:0016295 +name: myristoyl-[acyl-carrier-protein] hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate." [EC:3.1.2.14, MetaCyc:RXN-10727] +synonym: "myristoyl-[acyl-carrier protein] hydrolase activity" EXACT [] +synonym: "myristoyl-ACP hydrolase activity" EXACT [] +synonym: "tetradecanoyl-[acyl-carrier-protein] hydrolase activity" EXACT [] +synonym: "tetradecanoyl-ACP hydrolase activity" EXACT [] +xref: EC:3.1.2.14 +xref: KEGG_REACTION:R08159 +xref: MetaCyc:RXN-10727 +is_a: GO:0016297 ! acyl-[acyl-carrier-protein] hydrolase activity + +[Term] +id: GO:0016296 +name: palmitoyl-[acyl-carrier-protein] hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate." [EC:3.1.2.14, MetaCyc:RXN-9549] +synonym: "palmitoyl-[acyl-carrier protein] hydrolase activity" EXACT [] +synonym: "palmitoyl-ACP hydrolase activity" EXACT [] +xref: EC:3.1.2.14 +xref: KEGG_REACTION:R08162 +xref: MetaCyc:RXN-9549 +is_a: GO:0016297 ! acyl-[acyl-carrier-protein] hydrolase activity + +[Term] +id: GO:0016297 +name: acyl-[acyl-carrier-protein] hydrolase activity +namespace: molecular_function +alt_id: GO:0010281 +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid." [EC:3.1.2.14, MetaCyc:RXN-7902] +synonym: "acyl-[acyl-carrier protein] hydrolase activity" EXACT [] +synonym: "acyl-ACP hydrolase activity" EXACT [] +synonym: "acyl-ACP thioesterase activity" EXACT [] +synonym: "acyl-ACP-hydrolase activity" EXACT [EC:3.1.2.14] +synonym: "acyl-acyl carrier protein hydrolase activity" EXACT [EC:3.1.2.14] +synonym: "acyl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.14] +synonym: "S-acyl fatty acid synthase thioesterase activity" EXACT [EC:3.1.2.14] +xref: EC:3.1.2.14 +xref: MetaCyc:RXN-7902 +xref: Reactome:R-HSA-5655955 "OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer" +is_a: GO:0004312 ! fatty acid synthase activity +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0016298 +name: lipase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a lipid or phospholipid." [GOC:mah] +subset: goslim_aspergillus +subset: goslim_chembl +subset: goslim_drosophila +xref: EC:3.1.1 +xref: Reactome:R-HSA-163402 "diacylglycerol + H2O -> 2-acylglycerol + fatty acid" +xref: Reactome:R-HSA-163432 "cholesterol ester + H2O -> cholesterol + fatty acid" +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0016299 +name: obsolete regulator of G-protein signaling activity +namespace: molecular_function +def: "OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form." [GOC:curators] +comment: This term was made obsolete because it refers to a combination of a function and a process. +synonym: "regulator of G protein signaling activity" EXACT [] +synonym: "regulator of G protein signalling activity" EXACT [] +synonym: "regulator of G-protein signaling activity" EXACT [] +synonym: "regulator of G-protein signalling activity" EXACT [] +synonym: "RGS" EXACT [] +is_obsolete: true +consider: GO:0005095 +consider: GO:0034260 +consider: GO:0045744 + +[Term] +id: GO:0016300 +name: tRNA (uracil) methyltransferase activity +namespace: molecular_function +alt_id: GO:0016431 +def: "Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule." [GOC:mah] +comment: Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698). +synonym: "tRNA (uridine) methyltransferase activity" EXACT [] +is_a: GO:0008175 ! tRNA methyltransferase activity + +[Term] +id: GO:0016301 +name: kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] +comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_plant +subset: goslim_yeast +synonym: "phosphokinase activity" EXACT [] +xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" +xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups +relationship: part_of GO:0016310 ! phosphorylation + +[Term] +id: GO:0016303 +name: 1-phosphatidylinositol-3-kinase activity +namespace: molecular_function +alt_id: GO:0004429 +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+)." [EC:2.7.1.137, RHEA:12709] +synonym: "1-phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity" EXACT [EC:2.7.1.137] +synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] +synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] +synonym: "phosphatidylinositol 3-kinase activity, class III" NARROW [] +synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] +synonym: "PI3-kinase activity" EXACT [EC:2.7.1.137] +synonym: "PI3K" EXACT [] +synonym: "PtdIns-3-kinase activity" EXACT [EC:2.7.1.137] +synonym: "type I phosphatidylinositol kinase activity" NARROW [EC:2.7.1.137] +synonym: "type III phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.137] +synonym: "Vps34p" RELATED [EC:2.7.1.137] +xref: EC:2.7.1.137 +xref: KEGG_REACTION:R03362 +xref: MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN +xref: Reactome:R-HSA-109699 "PI3K-containing complexes phosphorylate PIP2 to PIP3" +xref: Reactome:R-HSA-1675939 "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane" +xref: Reactome:R-HSA-1675961 "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane" +xref: Reactome:R-HSA-1676024 "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane" +xref: Reactome:R-HSA-5672012 "Beclin-1 complex phosphorylates PtdIns" +xref: Reactome:R-HSA-6798174 "PIK3C3:PIK3R4 phosphorylates PI to PI3P" +xref: RHEA:12709 +is_a: GO:0035004 ! phosphatidylinositol 3-kinase activity +is_a: GO:0052742 ! phosphatidylinositol kinase activity +relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process + +[Term] +id: GO:0016304 +name: obsolete phosphatidylinositol 3-kinase activity, class I +namespace: molecular_function +def: "OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity." [PMID:9759495] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "phosphatidylinositol 3-kinase activity, class I" EXACT [] +is_obsolete: true +consider: GO:0016303 +consider: GO:0035005 +consider: GO:0046934 + +[Term] +id: GO:0016305 +name: obsolete phosphatidylinositol 3-kinase activity, class II +namespace: molecular_function +def: "OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine." [PMID:9759495] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "phosphatidylinositol 3-kinase activity, class II" EXACT [] +synonym: "PI3KC2" EXACT [] +is_obsolete: true +consider: GO:0016303 +consider: GO:0035005 +consider: GO:0046934 + +[Term] +id: GO:0016306 +name: obsolete phosphatidylinositol 3-kinase activity, class III +namespace: molecular_function +def: "OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol." [PMID:9759495] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "phosphatidylinositol 3-kinase activity, class III" EXACT [] +is_obsolete: true +replaced_by: GO:0016303 + +[Term] +id: GO:0016307 +name: phosphatidylinositol phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate." [EC:2.7.1.-, PMID:9759495] +synonym: "phosphatidylinositol monophosphate kinase activity" EXACT [GOC:bf] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +relationship: part_of GO:0046854 ! phosphatidylinositol phosphorylation + +[Term] +id: GO:0016308 +name: 1-phosphatidylinositol-4-phosphate 5-kinase activity +namespace: molecular_function +alt_id: GO:0004431 +alt_id: GO:0045215 +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.68, RHEA:14425] +synonym: "1-phosphatidylinositol-4-phosphate kinase activity" BROAD [] +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA" NARROW [] +synonym: "1-phosphatidylinositol-4-phosphate kinase, class IB" NARROW [] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.68] +synonym: "diphosphoinositide kinase activity" BROAD [EC:2.7.1.68] +synonym: "phosphatidylinositol 4-phosphate kinase activity" BROAD [EC:2.7.1.68] +synonym: "phosphatidylinositol-4-phosphate 5-kinase activity" EXACT [EC:2.7.1.68] +synonym: "PIP kinase activity" BROAD [EC:2.7.1.68] +synonym: "PIP5K" EXACT [] +synonym: "PtdIns(4)P-5-kinase activity" EXACT [EC:2.7.1.68] +synonym: "type I PIP kinase activity" NARROW [EC:2.7.1.68] +xref: EC:2.7.1.68 +xref: KEGG_REACTION:R03469 +xref: MetaCyc:2.7.1.68-RXN +xref: Reactome:R-HSA-1676082 "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane" +xref: Reactome:R-HSA-3772436 "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2" +xref: Reactome:R-HSA-8868066 "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2" +xref: RHEA:14425 +is_a: GO:0016307 ! phosphatidylinositol phosphate kinase activity + +[Term] +id: GO:0016309 +name: 1-phosphatidylinositol-5-phosphate 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [EC:2.7.1.149] +synonym: "1-phosphatidylinositol-5-phosphate kinase" BROAD [] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity" EXACT [EC:2.7.1.149] +synonym: "PIP4K" EXACT [] +synonym: "type II PIP kinase activity" NARROW [EC:2.7.1.149] +xref: EC:2.7.1.149 +xref: MetaCyc:2.7.1.149-RXN +xref: Reactome:R-HSA-1675776 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane" +xref: Reactome:R-HSA-6811522 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus" +xref: RHEA:12280 +is_a: GO:0016307 ! phosphatidylinositol phosphate kinase activity + +[Term] +id: GO:0016310 +name: phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] +subset: goslim_chembl +subset: goslim_metagenomics +xref: Wikipedia:Phosphorylation +is_a: GO:0006796 ! phosphate-containing compound metabolic process + +[Term] +id: GO:0016311 +name: dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphoric (ester or anhydride) residues from a molecule." [ISBN:0198506732] +xref: Wikipedia:Dephosphorylation +is_a: GO:0006796 ! phosphate-containing compound metabolic process + +[Term] +id: GO:0016312 +name: inositol bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate." [GOC:hb] +xref: Reactome:R-HSA-6809561 "I(1,3)P2 is dephosphorylated into I1P by MTMR7" +xref: Reactome:R-HSA-6809565 "I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9" +is_a: GO:0052745 ! inositol phosphate phosphatase activity + +[Term] +id: GO:0016313 +name: obsolete inositol-1,4,5-trisphosphate phosphatase +namespace: molecular_function +def: "OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate." [GOC:hb] +comment: This term was made obsolete because it is a redundant grouping term with only one child. +synonym: "inositol-1,4,5-trisphosphate phosphatase" EXACT [] +is_obsolete: true +consider: GO:0046030 + +[Term] +id: GO:0016314 +name: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate." [EC:3.1.3.67] +synonym: "1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.67] +synonym: "MMAC1" RELATED [EC:3.1.3.67] +synonym: "phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.67] +synonym: "PI(3)P 3-phosphatase activity" EXACT [GOC:mah, PMID:15249580] +synonym: "PI(3,4,5)P3 3-phosphatase activity" EXACT [GOC:mah, PMID:15249580] +synonym: "PtdIns(3,4,5)P3 3-phosphatase activity" EXACT [GOC:mah, PMID:15249580] +xref: EC:3.1.3.67 +xref: MetaCyc:3.1.3.67-RXN +xref: Reactome:R-HSA-199456 "PTEN dephosphorylates PIP3" +xref: Reactome:R-HSA-202237 "Hydrolysis of PIP3 to PI(3,4)P2" +xref: Reactome:R-HSA-2317387 "PTEN cancer mutants do not dephosphorylate PIP3" +xref: RHEA:25017 +is_a: GO:0034594 ! phosphatidylinositol trisphosphate phosphatase activity + +[Term] +id: GO:0016316 +name: phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity +namespace: molecular_function +alt_id: GO:0004440 +def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate." [EC:3.1.3.66, GOC:hb] +synonym: "1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity" EXACT [EC:3.1.3.66] +synonym: "inositol polyphosphate 4-phosphatase type II activity" RELATED [EC:3.1.3.66] +xref: EC:3.1.3.66 +xref: MetaCyc:3.1.3.66-RXN +xref: Reactome:R-HSA-1676162 "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane" +xref: Reactome:R-HSA-1676164 "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane" +is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity +is_a: GO:0106017 ! phosphatidylinositol-3,4-bisphosphate phosphatase activity +relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process + +[Term] +id: GO:0016318 +name: ommatidial rotation +namespace: biological_process +def: "The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification." [PMID:10725247] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0042067 ! establishment of ommatidial planar polarity + +[Term] +id: GO:0016319 +name: mushroom body development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells." [PMID:8790424] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0016320 +name: endoplasmic reticulum membrane fusion +namespace: biological_process +def: "The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum." [GOC:elh, GOC:jid] +synonym: "ER membrane fusion" EXACT [] +is_a: GO:0007029 ! endoplasmic reticulum organization +is_a: GO:0090174 ! organelle membrane fusion + +[Term] +id: GO:0016321 +name: female meiosis chromosome segregation +namespace: biological_process +def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045132 ! meiotic chromosome segregation +intersection_of: GO:0098813 ! nuclear chromosome segregation +intersection_of: part_of GO:0007143 ! female meiotic nuclear division +relationship: part_of GO:0007143 ! female meiotic nuclear division + +[Term] +id: GO:0016322 +name: neuron remodeling +namespace: biological_process +def: "The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development." [GOC:hb] +synonym: "axon pruning" NARROW [GOC:sart, PMID:18267091] +synonym: "neuronal remodeling" EXACT [] +is_a: GO:0042551 ! neuron maturation + +[Term] +id: GO:0016323 +name: basolateral plasma membrane +namespace: cellular_component +def: "The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis." [GOC:go_curators] +is_a: GO:0098590 ! plasma membrane region + +[Term] +id: GO:0016324 +name: apical plasma membrane +namespace: cellular_component +def: "The region of the plasma membrane located at the apical end of the cell." [GOC:curators] +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0045177 ! apical part of cell + +[Term] +id: GO:0016325 +name: oocyte microtubule cytoskeleton organization +namespace: biological_process +alt_id: GO:0048130 +def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123] +synonym: "oocyte microtubule cytoskeleton organisation" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity +relationship: part_of GO:0007308 ! oocyte construction + +[Term] +id: GO:0016326 +name: obsolete kinesin motor activity +namespace: molecular_function +def: "OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules." [GOC:hb] +comment: This term was made obsolete because it represents a gene product. +synonym: "kinesin motor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0003777 + +[Term] +id: GO:0016327 +name: apicolateral plasma membrane +namespace: cellular_component +def: "The apical end of the lateral plasma membrane of epithelial cells." [GOC:hb] +synonym: "apical lateral plasma membrane" EXACT [PMID:24496625] +is_a: GO:0098590 ! plasma membrane region + +[Term] +id: GO:0016328 +name: lateral plasma membrane +namespace: cellular_component +def: "The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells." [GOC:hb, GOC:mah, GOC:pr] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0016329 +name: obsolete apoptosis regulator activity +namespace: molecular_function +def: "OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis." [GOC:jl] +comment: This term was made obsolete because it represents involvement in a biological process. +synonym: "apoptosis regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0042981 + +[Term] +id: GO:0016330 +name: second mitotic wave involved in compound eye morphogenesis +namespace: biological_process +def: "A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia." [PMID:11257224] +synonym: "second mitotic wave during compound eye morphogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0016331 +name: morphogenesis of embryonic epithelium +namespace: biological_process +def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0016332 +name: establishment or maintenance of polarity of embryonic epithelium +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo." [GOC:isa_complete, GOC:mah] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium + +[Term] +id: GO:0016333 +name: morphogenesis of follicular epithelium +namespace: biological_process +def: "The process in which the anatomical structures of a follicular epithelium are generated and organized." [GOC:jl] +is_a: GO:0002009 ! morphogenesis of an epithelium + +[Term] +id: GO:0016334 +name: establishment or maintenance of polarity of follicular epithelium +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet." [GOC:bf, GOC:mah] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +relationship: part_of GO:0016333 ! morphogenesis of follicular epithelium + +[Term] +id: GO:0016335 +name: morphogenesis of larval imaginal disc epithelium +namespace: biological_process +def: "The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized." [GOC:jl] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0002168 ! instar larval development +relationship: part_of GO:0007560 ! imaginal disc morphogenesis + +[Term] +id: GO:0016336 +name: establishment or maintenance of polarity of larval imaginal disc epithelium +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium." [GOC:jl, GOC:mah] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +relationship: part_of GO:0016335 ! morphogenesis of larval imaginal disc epithelium + +[Term] +id: GO:0016338 +name: calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules +namespace: biological_process +def: "The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction." [GOC:hb] +synonym: "calcium-independent cell adhesion molecule activity" RELATED [] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules + +[Term] +id: GO:0016339 +name: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules +namespace: biological_process +def: "The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction." [GOC:hb] +synonym: "calcium-dependent cell adhesion molecule activity" RELATED [] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules + +[Term] +id: GO:0016340 +name: calcium-dependent cell-matrix adhesion +namespace: biological_process +def: "The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction." [GOC:hb] +is_a: GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0016341 +name: obsolete other collagen +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it is a redundant grouping term. +synonym: "other collagen" EXACT [] +is_obsolete: true +replaced_by: GO:0005581 + +[Term] +id: GO:0016342 +name: catenin complex +namespace: cellular_component +def: "Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton." [ISBN:0198599323] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0019897 ! extrinsic component of plasma membrane + +[Term] +id: GO:0016343 +name: obsolete cytoskeletal anchoring activity +namespace: molecular_function +def: "OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane." [ISBN:0198599323] +comment: This term was made obsolete because it represents a biological process. +synonym: "cytoskeletal anchoring activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0016344 +name: meiotic chromosome movement towards spindle pole +namespace: biological_process +def: "The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis." [GOC:ai] +synonym: "chromosome migration to spindle pole during meiosis" EXACT [] +synonym: "chromosome movement towards spindle pole during meiosis" EXACT [] +synonym: "meiotic chromosome movement" BROAD [] +synonym: "meiotic chromosome movement to spindle pole" EXACT [] +is_a: GO:0051305 ! chromosome movement towards spindle pole +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051305 ! chromosome movement towards spindle pole +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0016345 +name: female meiotic chromosome movement towards spindle pole +namespace: biological_process +def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis." [GOC:ai] +synonym: "chromosome movement towards spindle pole during female meiosis" EXACT [] +synonym: "female meiotic chromosome movement" BROAD [] +synonym: "female meiotic chromosome movement to spindle pole" EXACT [] +is_a: GO:0016344 ! meiotic chromosome movement towards spindle pole +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +intersection_of: GO:0051305 ! chromosome movement towards spindle pole +intersection_of: part_of GO:0007143 ! female meiotic nuclear division +relationship: part_of GO:0016321 ! female meiosis chromosome segregation + +[Term] +id: GO:0016346 +name: male meiotic chromosome movement towards spindle pole +namespace: biological_process +def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis." [GOC:ai] +synonym: "chromosome movement towards spindle pole during male meiosis" EXACT [] +synonym: "male meiotic chromosome movement" BROAD [] +synonym: "male meiotic chromosome movement to spindle pole" EXACT [] +is_a: GO:0016344 ! meiotic chromosome movement towards spindle pole +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +intersection_of: GO:0051305 ! chromosome movement towards spindle pole +intersection_of: part_of GO:0007140 ! male meiotic nuclear division +relationship: part_of GO:0007060 ! male meiosis chromosome segregation + +[Term] +id: GO:0016347 +name: obsolete calcium-independent cell adhesion molecule activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "calcium-independent cell adhesion molecule activity" EXACT [] +is_obsolete: true +consider: GO:0005515 +consider: GO:0007161 +consider: GO:0016021 +consider: GO:0016338 + +[Term] +id: GO:0016348 +name: imaginal disc-derived leg joint morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0036011 ! imaginal disc-derived leg segmentation + +[Term] +id: GO:0016351 +name: obsolete drug susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "drug susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0042493 + +[Term] +id: GO:0016352 +name: obsolete insecticide susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "insecticide susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0017085 + +[Term] +id: GO:0016353 +name: obsolete carbamate susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "carbamate susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046681 + +[Term] +id: GO:0016354 +name: obsolete cyclodiene susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "cyclodiene susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046682 + +[Term] +id: GO:0016355 +name: obsolete DDT susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. +synonym: "DDT susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046680 + +[Term] +id: GO:0016356 +name: obsolete organophosphorus susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "organophosphorus susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046683 + +[Term] +id: GO:0016357 +name: obsolete pyrethroid susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "pyrethroid susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046684 + +[Term] +id: GO:0016358 +name: dendrite development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure." [GOC:aruk, GOC:bc, GOC:jl, ISBN:0198506732, PMID:22683681] +is_a: GO:0031175 ! neuron projection development +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0016360 +name: sensory organ precursor cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +synonym: "sense organ precursor cell fate determination" EXACT [GOC:dph] +is_a: GO:0060582 ! cell fate determination involved in pattern specification +relationship: part_of GO:0008052 ! sensory organ boundary specification + +[Term] +id: GO:0016361 +name: activin receptor activity, type I +namespace: molecular_function +def: "Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals." [GOC:mah, PMID:8622651] +synonym: "type I activin receptor activity" EXACT [] +is_a: GO:0017002 ! activin-activated receptor activity + +[Term] +id: GO:0016362 +name: activin receptor activity, type II +namespace: molecular_function +def: "Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor." [GOC:mah, PMID:8622651] +synonym: "type II activin receptor activity" EXACT [] +xref: Reactome:R-HSA-201443 "Type II receptor phosphorylates type I receptor" +is_a: GO:0017002 ! activin-activated receptor activity + +[Term] +id: GO:0016363 +name: nuclear matrix +namespace: cellular_component +def: "The dense fibrillar network lying on the inner side of the nuclear membrane." [ISBN:0582227089] +synonym: "nucleoskeleton" EXACT [] +xref: Wikipedia:Nuclear_matrix +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0034399 ! nuclear periphery + +[Term] +id: GO:0016401 +name: palmitoyl-CoA oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide." [GOC:jsg] +xref: EC:1.3.3 +is_a: GO:0003997 ! acyl-CoA oxidase activity + +[Term] +id: GO:0016402 +name: pristanoyl-CoA oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide." [GOC:jsg] +xref: EC:1.3.3 +xref: Reactome:R-HSA-389889 "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA" +xref: Reactome:R-HSA-389891 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)" +is_a: GO:0003997 ! acyl-CoA oxidase activity + +[Term] +id: GO:0016403 +name: dimethylargininase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline." [EC:3.5.3.18] +synonym: "dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] +synonym: "N(G),N(G)-dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] +synonym: "NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity" EXACT [EC:3.5.3.18] +synonym: "NG,NG-dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] +xref: EC:3.5.3.18 +xref: MetaCyc:DIMETHYLARGININASE-RXN +xref: Reactome:R-HSA-5693373 "DDAH1,2 hydrolyses ADMA to DMA and L-Cit" +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0016404 +name: 15-hydroxyprostaglandin dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+." [EC:1.1.1.141] +synonym: "(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity" EXACT [EC:1.1.1.141] +synonym: "11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity" EXACT [EC:1.1.1.141] +synonym: "15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] +synonym: "15-hydroxyprostanoic dehydrogenase activity" EXACT [EC:1.1.1.141] +synonym: "15-OH-PGDH" RELATED [EC:1.1.1.141] +synonym: "NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)" EXACT [EC:1.1.1.141] +synonym: "NAD-specific 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] +synonym: "prostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] +xref: EC:1.1.1.141 +xref: MetaCyc:1.1.1.141-RXN +xref: Reactome:R-HSA-2161662 "PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD" +xref: Reactome:R-HSA-2161779 "LXA4 is oxidised to 15k-LXA4 by HPGD" +xref: Reactome:R-HSA-9023968 "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1" +xref: Reactome:R-HSA-9024766 "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1" +xref: RHEA:11876 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016405 +name: CoA-ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA." [GOC:ai] +xref: Reactome:R-HSA-159443 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate" +xref: Reactome:R-HSA-159567 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate" +xref: Reactome:R-HSA-177157 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate" +xref: Reactome:R-HSA-6798345 "GCAT:PXLP dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA" +is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds + +[Term] +id: GO:0016406 +name: carnitine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0016407 +name: acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acetyl group to an acceptor molecule." [GOC:ai] +synonym: "acetylase activity" EXACT [] +xref: Reactome:R-HSA-5628871 "BRD7 promotes EP300-mediated acetylation of TP53" +xref: Reactome:R-HSA-5660660 "p300 acetylates RELA subunit" +xref: Reactome:R-HSA-5682044 "KAT5 acetylates ATM at DNA DSBs" +xref: Reactome:R-HSA-6792712 "KAT5 acetylates ATM at shortened telomeres" +xref: Reactome:R-HSA-6805638 "KAT6A acetylates TP53" +xref: Reactome:R-HSA-73736 "Acetylation of SL1" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016408 +name: C-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016409 +name: palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule." [GOC:ai] +xref: Reactome:R-HSA-203567 "palmitoylation of eNOS" +xref: Reactome:R-HSA-5686304 "ZDHHC2 transfers PALM from PALM-CoA to CKAP4" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016410 +name: N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] +xref: Reactome:R-HSA-177160 "phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016411 +name: acylglycerol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule." [GOC:ai] +xref: Reactome:R-HSA-1482647 "2-MAG and DAG are transacylated to TAG by PNPLA2/3" +xref: Reactome:R-HSA-1482654 "2-MAG is transacylated to DAG by PNPLA2/3" +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0016412 +name: serine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule." [GOC:ai] +xref: EC:2.3.1.30 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0016413 +name: O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0016414 +name: O-octanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016415 ! octanoyltransferase activity + +[Term] +id: GO:0016415 +name: octanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule." [GOC:ai] +xref: EC:2.3.1.181 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016416 +name: O-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +xref: Reactome:R-HSA-2404137 "LRAT esterifies RBP1:atROL and FACYLs to atREs" +xref: Reactome:R-HSA-2453855 "LRAT esterifies RBP1:atROL and FACYLs to atREs" +xref: Reactome:R-HSA-2466710 "Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs" +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016409 ! palmitoyltransferase activity + +[Term] +id: GO:0016417 +name: S-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016418 +name: S-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule." [GOC:ai] +xref: EC:2.3.1.38 +is_a: GO:0016407 ! acetyltransferase activity +is_a: GO:0016417 ! S-acyltransferase activity + +[Term] +id: GO:0016419 +name: S-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule." [GOC:ai] +xref: EC:2.3.1.39 +is_a: GO:0016417 ! S-acyltransferase activity +is_a: GO:0016420 ! malonyltransferase activity + +[Term] +id: GO:0016420 +name: malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016421 +name: CoA carboxylase activity +namespace: molecular_function +def: "Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [GOC:mah] +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0016422 +name: mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am." [EC:2.1.1.62] +synonym: "messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity" EXACT [EC:2.1.1.62] +synonym: "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.62] +synonym: "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.62] +xref: EC:2.1.1.62 +xref: MetaCyc:2.1.1.62-RXN +is_a: GO:0008174 ! mRNA methyltransferase activity + +[Term] +id: GO:0016423 +name: tRNA (guanine) methyltransferase activity +namespace: molecular_function +alt_id: GO:0016424 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine." [GOC:go-curators] +synonym: "tRNA (guanosine) methyltransferase activity" EXACT [] +is_a: GO:0008175 ! tRNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0016426 +name: tRNA (adenine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine." [GOC:go-curators] +is_a: GO:0008175 ! tRNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0016427 +name: tRNA (cytosine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine." [GOC:go-curators] +is_a: GO:0008175 ! tRNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0016428 +name: tRNA (cytosine-5-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine." [EC:2.1.1.29] +synonym: "S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.29] +synonym: "transfer ribonucleate cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.29] +synonym: "transfer RNA cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.29] +xref: Reactome:R-HSA-6782388 "NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA)" +xref: Reactome:R-HSA-6782419 "TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp)" +xref: Reactome:R-HSA-6785409 "NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC)" +xref: Reactome:R-HSA-6785438 "NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC)" +xref: Reactome:R-HSA-8932765 "NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr)" +is_a: GO:0016427 ! tRNA (cytosine) methyltransferase activity + +[Term] +id: GO:0016429 +name: tRNA (adenine-N1-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine." [EC:2.1.1.36] +synonym: "1-methyladenine transfer RNA methyltransferase activity" EXACT [EC:2.1.1.36] +synonym: "adenine-1-methylase activity" EXACT [EC:2.1.1.36] +synonym: "S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity" EXACT [EC:2.1.1.36] +synonym: "S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.36] +synonym: "transfer ribonucleate adenine 1-methyltransferase activity" EXACT [EC:2.1.1.36] +synonym: "transfer RNA (adenine-1) methyltransferase activity" EXACT [EC:2.1.1.36] +xref: Reactome:R-HSA-6783492 "TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met)" +xref: Reactome:R-HSA-6787525 "TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58" +xref: Reactome:R-HSA-6787594 "TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9" +is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity + +[Term] +id: GO:0016430 +name: tRNA (adenine-N6-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine." [EC:2.1.1.55] +synonym: "S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.55] +synonym: "S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.55] +xref: EC:2.1.1.55 +xref: MetaCyc:TRNA-ADENINE-N6--METHYLTRANSFERASE-RXN +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity + +[Term] +id: GO:0016432 +name: tRNA-uridine aminocarboxypropyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine." [EC:2.5.1.25] +synonym: "S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity" EXACT [EC:2.5.1.25] +xref: EC:2.5.1.25 +xref: MetaCyc:2.5.1.25-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0016433 +name: rRNA (adenine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine." [GOC:go-curators] +is_a: GO:0008649 ! rRNA methyltransferase activity + +[Term] +id: GO:0016434 +name: rRNA (cytosine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine." [GOC:go-curators] +is_a: GO:0008649 ! rRNA methyltransferase activity + +[Term] +id: GO:0016435 +name: rRNA (guanine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine." [EC:2.1.1.-] +is_a: GO:0008649 ! rRNA methyltransferase activity + +[Term] +id: GO:0016436 +name: rRNA (uridine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine." [GOC:go-curators] +is_a: GO:0008649 ! rRNA methyltransferase activity + +[Term] +id: GO:0016437 +name: tRNA cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1)." [EC:2.7.7.21] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "-C-C-A pyrophosphorylase" BROAD [EC:2.7.7.21] +synonym: "ATP (CTP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "ATP(CTP)-tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "ATP(CTP):tRNA nucleotidyltransferase activity" BROAD [EC:2.7.7.21] +synonym: "CTP(ATP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "CTP:tRNA cytidylyltransferase activity" BROAD [] +synonym: "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase" BROAD [EC:2.7.7.21] +synonym: "ribonucleic cytidylyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleate adenylyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleate cytidylyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleate nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleic acid nucleotidyl transferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleic adenylyl (cytidylyl) transferase" BROAD [EC:2.7.7.21] +synonym: "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer RNA adenylyltransferase" BROAD [EC:2.7.7.21] +synonym: "transfer-RNA nucleotidyltransferase" BROAD [EC:2.7.7.21] +synonym: "tRNA adenylyl(cytidylyl)transferase" BROAD [EC:2.7.7.21] +synonym: "tRNA CCA-diphosphorylase activity" RELATED [EC:2.7.7.21] +synonym: "tRNA CCA-pyrophosphorylase activity" RELATED [EC:2.7.7.21] +xref: EC:2.7.7.21 +xref: MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN +is_a: GO:0070567 ! cytidylyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0016438 +name: tRNA-queuosine beta-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine." [EC:2.4.1.110] +synonym: "GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.110] +xref: EC:2.4.1.110 +xref: MetaCyc:2.4.1.110-RXN +is_a: GO:0000030 ! mannosyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0016441 +name: posttranscriptional gene silencing +namespace: biological_process +def: "The inactivation of gene expression by a posttranscriptional mechanism." [GOC:mah, PMID:15020054] +synonym: "cosuppression" RELATED [] +synonym: "post-transcriptional gene silencing" EXACT [GOC:vw] +synonym: "PTGS" EXACT [] +synonym: "quelling" EXACT [] +xref: Wikipedia:Post_transcriptional_gene_silencing +is_a: GO:0010608 ! posttranscriptional regulation of gene expression +is_a: GO:0040029 ! regulation of gene expression, epigenetic + +[Term] +id: GO:0016442 +name: RISC complex +namespace: cellular_component +alt_id: GO:0035068 +def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation." [PMID:10749213, PMID:15145345] +synonym: "micro-ribonucleoprotein complex" RELATED [] +synonym: "miRNP complex" RELATED [] +synonym: "RNA-induced silencing complex" EXACT [] +xref: Wikipedia:RNA-induced_silencing_complex +is_a: GO:0031332 ! RNAi effector complex + +[Term] +id: GO:0016443 +name: bidentate ribonuclease III activity +namespace: molecular_function +def: "Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference." [PMID:15242644] +synonym: "bidentate RNase III activity" EXACT [] +xref: EC:3.1.26 +is_a: GO:0004525 ! ribonuclease III activity + +[Term] +id: GO:0016444 +name: somatic cell DNA recombination +namespace: biological_process +def: "Recombination occurring within or between DNA molecules in somatic cells." [GOC:ma] +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0016445 +name: somatic diversification of immunoglobulins +namespace: biological_process +def: "The somatic process that results in the generation of sequence diversity of immunoglobulins." [GOC:add, GOC:ma, ISBN:0781735149] +synonym: "somatic diversification of antibodies" EXACT [] +is_a: GO:0002200 ! somatic diversification of immune receptors +relationship: part_of GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0016446 +name: somatic hypermutation of immunoglobulin genes +namespace: biological_process +def: "Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins." [GOC:add, ISBN:0781735149, PMID:11205330, PMID:11205333, PMID:14975236, PMID:7813007] +synonym: "somatic hypermutation of antibody genes" EXACT [] +is_a: GO:0002566 ! somatic diversification of immune receptors via somatic mutation +is_a: GO:0016445 ! somatic diversification of immunoglobulins + +[Term] +id: GO:0016447 +name: somatic recombination of immunoglobulin gene segments +namespace: biological_process +def: "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus." [GOC:add, ISBN:0781735149] +synonym: "somatic recombination of antibody gene segments" EXACT [] +is_a: GO:0002562 ! somatic diversification of immune receptors via germline recombination within a single locus +is_a: GO:0016445 ! somatic diversification of immunoglobulins + +[Term] +id: GO:0016453 +name: C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016407 ! acetyltransferase activity +is_a: GO:0016408 ! C-acyltransferase activity + +[Term] +id: GO:0016454 +name: C-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016408 ! C-acyltransferase activity +is_a: GO:0016409 ! palmitoyltransferase activity + +[Term] +id: GO:0016456 +name: X chromosome located dosage compensation complex, transcription activating +namespace: cellular_component +def: "An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster." [GOC:ma, GOC:mr, GOC:mtg_sensu, PMID:20622855, Wikipedia:XY_sex-determination_system] +synonym: "dosage compensation complex" BROAD [] +is_a: GO:0046536 ! dosage compensation complex +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0000805 ! X chromosome +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0016457 +name: dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster." [GOC:jl] +synonym: "dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome" RELATED [GOC:dph, GOC:tb] +is_a: GO:0042714 ! dosage compensation complex assembly +is_a: GO:0065004 ! protein-DNA complex assembly +intersection_of: GO:0042714 ! dosage compensation complex assembly +intersection_of: part_of GO:0009047 ! dosage compensation by hyperactivation of X chromosome +relationship: part_of GO:0009047 ! dosage compensation by hyperactivation of X chromosome + +[Term] +id: GO:0016458 +name: gene silencing +namespace: biological_process +def: "Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression." [GOC:dos, GOC:dph, GOC:jid, GOC:tb] +comment: This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class. +subset: goslim_drosophila +subset: goslim_pir +synonym: "long-term maintenance of gene inactivation" NARROW [] +xref: Wikipedia:Gene_silencing +is_a: GO:0009987 ! cellular process +is_a: GO:0010629 ! negative regulation of gene expression + +[Term] +id: GO:0016459 +name: myosin complex +namespace: cellular_component +def: "A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes." [GOC:mah, Wikipedia:Myosin] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0016460 +name: myosin II complex +namespace: cellular_component +def: "A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures." [Wikipedia:Myosin] +synonym: "conventional myosin" RELATED [] +is_a: GO:0016459 ! myosin complex + +[Term] +id: GO:0016461 +name: unconventional myosin complex +namespace: cellular_component +alt_id: GO:0005860 +def: "A portmanteau term for myosins other than myosin II." [GOC:ma] +comment: Note that this term is retained because it is widely used by biologists. +synonym: "non-muscle myosin" RELATED [] +is_a: GO:0016459 ! myosin complex + +[Term] +id: GO:0016462 +name: pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments." [EC:3.6.1.-, GOC:curators] +xref: Reactome:R-HSA-6810472 "NUDT13 hydrolyses AP6A to AP4 and ADP" +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0016463 +name: zinc transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out)." [EC:7.2.2.12] +synonym: "ATP phosphohydrolase (Zn2+-exporting)" EXACT [] +synonym: "P(1B)-type ATPase activity" NARROW [EC:7.2.2.12] +synonym: "P1B-type ATPase activity" EXACT [EC:7.2.2.12] +synonym: "zinc exporting ATPase activity" EXACT [] +synonym: "zinc-exporting ATPase activity" RELATED [] +synonym: "zinc-translocating P-type ATPase activity" BROAD [EC:7.2.2.12] +synonym: "Zn(2+)-exporting ATPase activity" EXACT [EC:7.2.2.12] +synonym: "Zn(II)-translocating P-type ATPase activity" EXACT [EC:7.2.2.12] +synonym: "Zn2+-exporting ATPase activity" EXACT [EC:7.2.2.12] +xref: EC:7.2.2.12 +xref: MetaCyc:3.6.3.5-RXN +xref: RHEA:20621 +is_a: GO:0015633 ! ATPase-coupled zinc transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism + +[Term] +id: GO:0016464 +name: chloroplast protein-transporting ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma." [EC:7.4.2.4] +synonym: "ATP phosphohydrolase (chloroplast protein-importing)" EXACT [EC:7.4.2.4] +synonym: "chloroplast protein ABC transporter" NARROW [] +xref: EC:7.4.2.4 +xref: MetaCyc:3.6.3.52-RXN +is_a: GO:0015462 ! ATPase-coupled protein transmembrane transporter activity + +[Term] +id: GO:0016465 +name: chaperonin ATPase complex +namespace: cellular_component +def: "Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts." [EC:3.6.4.9] +is_a: GO:0101031 ! chaperone complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0016466 +name: obsolete hydrogen-translocating A-type ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae." [TC:3.A.2.3.1] +comment: This term was made obsolete because it represents a gene product. +synonym: "hydrogen-translocating A-type ATPase activity" EXACT [] +synonym: "proton-translocating A-type ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0046961 + +[Term] +id: GO:0016467 +name: obsolete hydrogen-translocating F-type ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria." [TC:3.A.2.1.1, TC:3.A.2.1.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "ATP synthase" BROAD [] +synonym: "F1-ATPase activity" EXACT [] +synonym: "hydrogen-translocating F-type ATPase activity" EXACT [] +synonym: "proton-translocating F-type ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0046933 +consider: GO:0046961 + +[Term] +id: GO:0016468 +name: obsolete sodium-translocating F-type ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria." [TC:3.A.2.1.2] +comment: This term was made obsolete because it represents a gene product. +synonym: "ATP synthase" BROAD [] +synonym: "sodium-translocating F-type ATPase activity" EXACT [] +is_obsolete: true +consider: GO:0046932 +consider: GO:0046962 + +[Term] +id: GO:0016469 +name: proton-transporting two-sector ATPase complex +namespace: cellular_component +def: "A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible." [GOC:mah, ISBN:0716743663, PMID:16691483] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "hydrogen-transporting two-sector ATPase complex" EXACT [] +synonym: "vacuolar hydrogen-transporting ATPase" RELATED [] +is_a: GO:0098796 ! membrane protein complex + +[Term] +id: GO:0016471 +name: vacuolar proton-transporting V-type ATPase complex +namespace: cellular_component +def: "A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen." [GOC:mah, ISBN:0716743663, PMID:16449553] +comment: See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'. +synonym: "vacuolar hydrogen-translocating V-type ATPase complex" EXACT [] +is_a: GO:0033176 ! proton-transporting V-type ATPase complex +intersection_of: GO:0033176 ! proton-transporting V-type ATPase complex +intersection_of: part_of GO:0005774 ! vacuolar membrane +relationship: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0016472 +name: sodium ion-transporting two-sector ATPase complex +namespace: cellular_component +def: "A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis." [GOC:mah, PMID:14656431] +subset: goslim_pir +synonym: "sodium-transporting two-sector ATPase complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016021 ! integral component of membrane + +[Term] +id: GO:0016473 +name: sodium ion-transporting F-type ATPase complex +namespace: cellular_component +def: "A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism." [GOC:mah, PMID:14656431] +synonym: "sodium-translocating F-type ATPase complex" EXACT [] +is_a: GO:0016472 ! sodium ion-transporting two-sector ATPase complex + +[Term] +id: GO:0016474 +name: sodium ion-transporting V-type ATPase complex +namespace: cellular_component +def: "A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis." [GOC:mah, PMID:15802565] +synonym: "sodium-translocating V-type ATPase complex" EXACT [] +is_a: GO:0016472 ! sodium ion-transporting two-sector ATPase complex + +[Term] +id: GO:0016475 +name: detection of nuclear:cytoplasmic ratio +namespace: biological_process +def: "The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell." [GOC:jl] +synonym: "interpretation of nuclear:cytoplasmic ratio" EXACT [] +synonym: "sensing of nuclear:cytoplasmic ratio" EXACT [] +is_a: GO:0009726 ! detection of endogenous stimulus +relationship: part_of GO:0016049 ! cell growth + +[Term] +id: GO:0016476 +name: regulation of embryonic cell shape +namespace: biological_process +def: "Any process that modulates the surface configuration of an embryonic cell." [GOC:dph, GOC:tb] +synonym: "shape changes of embryonic cells" RELATED [GOC:dph, GOC:tb] +is_a: GO:0008360 ! regulation of cell shape +is_a: GO:0045995 ! regulation of embryonic development + +[Term] +id: GO:0016477 +name: cell migration +namespace: biological_process +def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] +xref: Wikipedia:Cell_migration +is_a: GO:0048870 ! cell motility + +[Term] +id: GO:0016479 +name: negative regulation of transcription by RNA polymerase I +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I." [GOC:go_curators] +synonym: "down regulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "downregulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "inhibition of transcription from RNA polymerase I promoter" NARROW [] +synonym: "negative regulation of transcription from Pol I promoter" EXACT [] +synonym: "negative regulation of transcription from RNA polymerase I promoter" EXACT [] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006360 ! transcription by RNA polymerase I +relationship: negatively_regulates GO:0006360 ! transcription by RNA polymerase I + +[Term] +id: GO:0016480 +name: negative regulation of transcription by RNA polymerase III +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III." [GOC:go_curators] +synonym: "down regulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "downregulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "inhibition of transcription from RNA polymerase III promoter" NARROW [] +synonym: "negative regulation of transcription from Pol III promoter" EXACT [] +synonym: "negative regulation of transcription from RNA polymerase III promoter" EXACT [] +is_a: GO:0006359 ! regulation of transcription by RNA polymerase III +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006383 ! transcription by RNA polymerase III +relationship: negatively_regulates GO:0006383 ! transcription by RNA polymerase III + +[Term] +id: GO:0016482 +name: cytosolic transport +namespace: biological_process +def: "The directed movement of substances or organelles within the cytosol." [GOC:ai] +is_a: GO:0046907 ! intracellular transport +intersection_of: GO:0006810 ! transport +intersection_of: occurs_in GO:0005829 ! cytosol +relationship: occurs_in GO:0005829 ! cytosol + +[Term] +id: GO:0016483 +name: tryptophan hydroxylase activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme tryptophase hydroxylase." [GOC:ai] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0004510 ! tryptophan 5-monooxygenase activity + +[Term] +id: GO:0016484 +name: obsolete proprotein convertase 2 activator activity +namespace: molecular_function +def: "OBSOLETE. Required for the maturation and activation of proprotein convertase 2." [GOC:ma, PMID:10749852] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "proprotein convertase 2 activator activity" EXACT [] +is_obsolete: true +consider: GO:0016504 + +[Term] +id: GO:0016485 +name: protein processing +namespace: biological_process +alt_id: GO:0051605 +def: "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein." [GOC:curators, GOC:jl, GOC:jsg] +subset: goslim_chembl +synonym: "peptidolysis during protein maturation" RELATED [GOC:mah] +synonym: "protein maturation by peptide bond cleavage" EXACT [GOC:bf] +synonym: "protein maturation by peptide bond hydrolysis" EXACT [GOC:mah] +synonym: "protein maturation by proteolysis" RELATED [GOC:mah] +is_a: GO:0006508 ! proteolysis +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0016486 +name: peptide hormone processing +namespace: biological_process +def: "The generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:mah] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0140448 ! signaling receptor ligand precursor processing + +[Term] +id: GO:0016487 +name: farnesol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol." [GOC:go_curators] +synonym: "farnesol metabolism" EXACT [] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0016093 ! polyprenol metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process + +[Term] +id: GO:0016488 +name: farnesol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol." [GOC:go_curators] +synonym: "farnesol breakdown" EXACT [] +synonym: "farnesol catabolism" EXACT [] +synonym: "farnesol degradation" EXACT [] +is_a: GO:0016095 ! polyprenol catabolic process +is_a: GO:0016107 ! sesquiterpenoid catabolic process +is_a: GO:0016487 ! farnesol metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0034310 ! primary alcohol catabolic process + +[Term] +id: GO:0016490 +name: structural constituent of peritrophic membrane +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "structural constituent of peritrophic matrix" RELATED [] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0016491 +name: oxidoreductase activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced." [GOC:go_curators] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_yeast +synonym: "oxidoreductase activity, acting on other substrates" NARROW [] +synonym: "redox activity" EXACT [] +xref: EC:1 +xref: Reactome:R-HSA-1614362 "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases" +xref: Reactome:R-HSA-209921 "Monoiodinated tyrosine can be deiodinated" +xref: Reactome:R-HSA-209960 "Diiodinated tyrosine can be deiodinated" +xref: Reactome:R-HSA-3095889 "MMACHC reduces Cbl" +xref: Reactome:R-HSA-390425 "FAR1 reduces PalmCoA to HXOL" +xref: Reactome:R-HSA-390438 "FAR2 reduces PalmCoA to HXOL" +xref: Reactome:R-HSA-5662660 "Dopachrome is transformed to DHICA by DCT" +xref: Reactome:R-HSA-8878581 "TYRP1 oxidises DHICA to IQCA" +xref: Reactome:R-HSA-8936442 "MARC1,MARC2 reduce N-hydroxylated compounds" +xref: Reactome:R-HSA-9020249 "Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6" +xref: Reactome:R-HSA-9020260 "Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5" +xref: Reactome:R-HSA-9024624 "Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6" +xref: Reactome:R-HSA-9024630 "Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5" +xref: Reactome:R-HSA-9025007 "Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1" +xref: Reactome:R-HSA-9026001 "Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA" +xref: Reactome:R-HSA-9026917 "Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA" +xref: Reactome:R-HSA-9027033 "Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA" +is_a: GO:0003824 ! catalytic activity +relationship: part_of GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0016492 +name: G protein-coupled neurotensin receptor activity +namespace: molecular_function +def: "Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state." [PMID:10390649] +synonym: "G protein coupled neurotensin receptor activity" EXACT [] +synonym: "G-protein coupled neurotensin receptor activity" EXACT [] +synonym: "neurotensin receptor activity, G protein coupled" EXACT [] +synonym: "neurotensin receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0016493 +name: C-C chemokine receptor activity +namespace: molecular_function +def: "Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif." [GOC:signaling, PMID:8662823] +is_a: GO:0004950 ! chemokine receptor activity +relationship: has_part GO:0019957 ! C-C chemokine binding + +[Term] +id: GO:0016494 +name: C-X-C chemokine receptor activity +namespace: molecular_function +def: "Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif." [GOC:signaling, PMID:8662823] +is_a: GO:0004950 ! chemokine receptor activity +relationship: has_part GO:0019958 ! C-X-C chemokine binding + +[Term] +id: GO:0016495 +name: C-X3-C chemokine receptor activity +namespace: molecular_function +def: "Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif." [GOC:dph, GOC:signaling] +is_a: GO:0004950 ! chemokine receptor activity +relationship: has_part GO:0019960 ! C-X3-C chemokine binding + +[Term] +id: GO:0016496 +name: substance P receptor activity +namespace: molecular_function +def: "Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732] +is_a: GO:0004995 ! tachykinin receptor activity + +[Term] +id: GO:0016497 +name: substance K receptor activity +namespace: molecular_function +def: "Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732] +synonym: "neurokinin A receptor activity" EXACT [] +synonym: "neuromedin L receptor activity" EXACT [] +is_a: GO:0004995 ! tachykinin receptor activity + +[Term] +id: GO:0016498 +name: neuromedin K receptor activity +namespace: molecular_function +def: "Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity." [GOC:mah, ISBN:0198506732] +synonym: "neurokinin B receptor activity" EXACT [] +is_a: GO:0004995 ! tachykinin receptor activity + +[Term] +id: GO:0016499 +name: orexin receptor activity +namespace: molecular_function +def: "Combining with orexin to initiate a change in cell activity." [GOC:ai] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0016500 +name: protein-hormone receptor activity +namespace: molecular_function +def: "Combining with a protein hormone to initiate a change in cell activity." [GOC:mah] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0016501 +name: prostacyclin receptor activity +namespace: molecular_function +alt_id: GO:0004959 +def: "Combining with prostacyclin (PGI(2)) to initiate a change in cell activity." [ISBN:0198506732] +synonym: "PGI receptor activity" RELATED [] +synonym: "PGI(2) receptor activity" EXACT [] +synonym: "prostaglandin I receptor activity" EXACT [] +is_a: GO:0004955 ! prostaglandin receptor activity + +[Term] +id: GO:0016502 +name: nucleotide receptor activity +namespace: molecular_function +def: "Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule." [GOC:signaling, ISBN:0198506732] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0000166 ! nucleotide binding + +[Term] +id: GO:0016503 +name: pheromone receptor activity +namespace: molecular_function +def: "Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior." [GOC:hjd, ISBN:0198506732] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: has_part GO:0005550 ! pheromone binding + +[Term] +id: GO:0016504 +name: peptidase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds." [GOC:ai] +synonym: "protease activator activity" NARROW [GOC:mah] +xref: Reactome:R-HSA-168865 "NA activation of TGF-beta" +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0061134 ! peptidase regulator activity +relationship: part_of GO:0010952 ! positive regulation of peptidase activity +relationship: positively_regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0016505 +name: peptidase activator activity involved in apoptotic process +namespace: molecular_function +def: "Increases the activity of a peptidase that is involved in the apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] +synonym: "apoptotic protease activator activity" NARROW [] +is_a: GO:0016504 ! peptidase activator activity +intersection_of: GO:0016504 ! peptidase activator activity +intersection_of: part_of GO:0006915 ! apoptotic process +relationship: part_of GO:0006915 ! apoptotic process + +[Term] +id: GO:0016506 +name: obsolete apoptosis activator activity +namespace: molecular_function +def: "OBSOLETE. The function held by products which directly activate any step in the process of apoptosis." [GOC:hb] +comment: This term was made obsolete because it represents involvement in a biological process. +synonym: "apoptosis activator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0006915 + +[Term] +id: GO:0016507 +name: mitochondrial fatty acid beta-oxidation multienzyme complex +namespace: cellular_component +def: "A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix." [GOC:ma] +synonym: "fatty acid beta-oxidation multienzyme complex" BROAD [GOC:imk] +synonym: "trifunctional enzyme" RELATED [] +is_a: GO:0036125 ! fatty acid beta-oxidation multienzyme complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0036125 ! fatty acid beta-oxidation multienzyme complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0016508 +name: long-chain-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms." [EC:4.2.1.74] +synonym: "long-chain enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.74] +synonym: "long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.74] +xref: EC:4.2.1.74 +xref: MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN +xref: Reactome:R-HSA-2066778 "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA" +xref: Reactome:R-HSA-2066780 "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA" +xref: Reactome:R-HSA-389986 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA" +xref: Reactome:R-HSA-390252 "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA" +xref: Reactome:R-HSA-6809263 "EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA" +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0016509 +name: long-chain-3-hydroxyacyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [EC:1.1.1.211, GOC:pde] +comment: Also see '3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857'. +synonym: "beta-hydroxyacyl-CoA dehydrogenase activity" EXACT [EC:1.1.1.211] +synonym: "LCHAD" RELATED [EC:1.1.1.211] +synonym: "long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.211] +synonym: "long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.211] +xref: EC:1.1.1.211 +xref: MetaCyc:1.1.1.211-RXN +xref: Reactome:R-HSA-548818 "HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA" +is_a: GO:0003857 ! 3-hydroxyacyl-CoA dehydrogenase activity + +[Term] +id: GO:0016511 +name: obsolete endothelin-converting enzyme activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "endothelin-converting enzyme activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0016512 +name: obsolete endothelin-converting enzyme 1 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor." [EC:3.4.24.71] +comment: This term was made obsolete because it represents a gene product. +synonym: "ECE-1 activity" EXACT [EC:3.4.24.71] +synonym: "endothelin-converting enzyme 1 activity" EXACT [] +xref: EC:3.4.24.71 +xref: MetaCyc:3.4.24.71-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0016513 +name: core-binding factor complex +namespace: cellular_component +def: "A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit." [PMID:15156179, PMID:8497254] +synonym: "AML1 complex" NARROW [] +synonym: "CBF complex" EXACT [] +synonym: "PEPB2 complex" NARROW [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0016514 +name: SWI/SNF complex +namespace: cellular_component +def: "A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof." [GOC:bhm, PMID:12672490] +synonym: "SWI-SNF complex" EXACT [GOC:mah] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex + +[Term] +id: GO:0016515 +name: interleukin-13 receptor activity +namespace: molecular_function +def: "Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-13 receptor activity" EXACT [GOC:mah] +synonym: "IL-13R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019973 ! interleukin-13 binding +relationship: part_of GO:0035772 ! interleukin-13-mediated signaling pathway + +[Term] +id: GO:0016516 +name: interleukin-4 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor." [PMID:10358772] +synonym: "IL-4 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0016517 +name: interleukin-12 receptor activity +namespace: molecular_function +def: "Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-12 receptor activity" EXACT [GOC:mah] +synonym: "IL-12R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019972 ! interleukin-12 binding +relationship: part_of GO:0035722 ! interleukin-12-mediated signaling pathway + +[Term] +id: GO:0016518 +name: interleukin-14 receptor activity +namespace: molecular_function +def: "Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-14 receptor activity" EXACT [GOC:mah] +synonym: "IL-14R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019974 ! interleukin-14 binding + +[Term] +id: GO:0016519 +name: gastric inhibitory peptide receptor activity +namespace: molecular_function +def: "Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein." [GOC:mah, PMID:8243312] +synonym: "GIP receptor activity" EXACT [PMID:19251046] +synonym: "glucose-dependent insulinotropic polypeptide receptor activity" EXACT [PMID:19251046] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: part_of GO:0038192 ! gastric inhibitory peptide signaling pathway + +[Term] +id: GO:0016520 +name: growth hormone-releasing hormone receptor activity +namespace: molecular_function +def: "Combining with growth hormone-releasing hormone to initiate a change in cell activity." [PMID:12529933] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0016521 +name: pituitary adenylate cyclase activating polypeptide activity +namespace: molecular_function +def: "The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation." [GOC:mah, PMID:19805477] +synonym: "pituitary adenylyl cyclase activating polypeptide activity" EXACT [] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0016524 +name: latrotoxin receptor activity +namespace: molecular_function +def: "Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling, PMID:10025961] +synonym: "latrophilin" NARROW [] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0016525 +name: negative regulation of angiogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators] +synonym: "down regulation of angiogenesis" EXACT [] +synonym: "down-regulation of angiogenesis" EXACT [] +synonym: "downregulation of angiogenesis" EXACT [] +synonym: "inhibition of angiogenesis" NARROW [] +is_a: GO:0045765 ! regulation of angiogenesis +is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001525 ! angiogenesis +relationship: negatively_regulates GO:0001525 ! angiogenesis + +[Term] +id: GO:0016527 +name: obsolete brain-specific angiogenesis inhibitor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it is based on anatomical information, and describes at least one gene product. It has also never been defined. +synonym: "brain-specific angiogenesis inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0004930 + +[Term] +id: GO:0016528 +name: sarcoplasm +namespace: cellular_component +def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684] +xref: Wikipedia:Sarcoplasm +is_a: GO:0005737 ! cytoplasm +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0016529 +name: sarcoplasmic reticulum +namespace: cellular_component +alt_id: GO:0008221 +def: "A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage." [GOC:mtg_muscle, ISBN:0124325653, ISBN:0198547684] +comment: See also the cellular component terms 'sarcoplasm ; GO:0016528', 'nuclear envelope ; GO:0005635' and 'endoplasmic reticulum ; GO:0005783'. +xref: Wikipedia:Endoplasmic_reticulum#Sarcoplasmic_reticulum +is_a: GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0016528 ! sarcoplasm + +[Term] +id: GO:0016530 +name: metallochaperone activity +namespace: molecular_function +def: "Directly binding to and delivering metal ions to a target protein." [PMID:11739376] +subset: goslim_pir +is_a: GO:0140104 ! molecular carrier activity + +[Term] +id: GO:0016531 +name: copper chaperone activity +namespace: molecular_function +def: "Directly binding to and delivering copper ions to a target protein." [PMID:10790544, PMID:11739376] +is_a: GO:0005507 ! copper ion binding +is_a: GO:0016530 ! metallochaperone activity + +[Term] +id: GO:0016532 +name: superoxide dismutase copper chaperone activity +namespace: molecular_function +def: "A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity." [GOC:vw, http://link.springer-ny.com/link/service/journals/00335/papers/0011005/00110409.html, PMID:15064408, PMID:9295278] +comment: See also the molecular function term 'superoxide dismutase activity ; GO:0004784'. +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0016531 ! copper chaperone activity +relationship: positively_regulates GO:0004784 ! superoxide dismutase activity + +[Term] +id: GO:0016533 +name: protein kinase 5 complex +namespace: cellular_component +def: "A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent." [PMID:15689152] +synonym: "cyclin-dependent protein kinase 5 holoenzyme complex" RELATED [] +is_a: GO:1902554 ! serine/threonine protein kinase complex + +[Term] +id: GO:0016536 +name: obsolete cyclin-dependent protein kinase 5 activator regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulation of the activity of cyclin-dependent protein kinase 5 activator." [GOC:ai] +comment: This term was made obsolete because it refers to a specific gene product. +synonym: "cyclin-dependent protein kinase 5 activator regulator activity" EXACT [] +synonym: "cyclin-dependent protein kinase 5 activator, intrinsic regulator activity" NARROW [] +is_obsolete: true + +[Term] +id: GO:0016538 +name: cyclin-dependent protein serine/threonine kinase regulator activity +namespace: molecular_function +alt_id: GO:0003751 +alt_id: GO:0003752 +alt_id: GO:0003753 +def: "Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins." [GOC:pr, GOC:rn, PMID:7877684, PMID:9442875] +synonym: "cyclin" BROAD [] +synonym: "cyclin-dependent protein kinase regulator activity" BROAD [] +synonym: "cyclin-dependent protein kinase, intrinsic regulator activity" NARROW [] +synonym: "G1/S-specific cyclin" NARROW [] +synonym: "G2/M-specific cyclin" NARROW [] +xref: EC:2.7.1 +xref: Reactome:R-HSA-3215385 "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77" +is_a: GO:0019887 ! protein kinase regulator activity +relationship: part_of GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0016539 +name: intein-mediated protein splicing +namespace: biological_process +def: "The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues." [GOC:ma, http://www.neb.com/neb/inteins.html] +synonym: "intein" RELATED [] +is_a: GO:0030908 ! protein splicing + +[Term] +id: GO:0016540 +name: protein autoprocessing +namespace: biological_process +def: "Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein." [GOC:ai, PMID:9335337] +subset: goslim_chembl +is_a: GO:0016485 ! protein processing + +[Term] +id: GO:0016541 +name: obsolete intein +namespace: molecular_function +def: "OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity." [GOC:mah, http://www.neb.com/neb/inteins.html, PMID:8165123] +comment: This term was made obsolete because it refers to a protein sequence feature. +synonym: "intein" EXACT [] +is_obsolete: true +consider: GO:0004519 +consider: GO:0016539 + +[Term] +id: GO:0016543 +name: male courtship behavior, orientation prior to leg tapping and wing vibration +namespace: biological_process +def: "The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster." [GOC:sensu, PMID:11092827] +synonym: "male courtship behavior, orientation" RELATED [] +synonym: "male courtship behaviour, orientation" RELATED [] +synonym: "male courtship behaviour, orientation prior to leg tapping and wing vibration" RELATED [] +is_a: GO:0008049 ! male courtship behavior + +[Term] +id: GO:0016544 +name: male courtship behavior, tapping to detect pheromone +namespace: biological_process +def: "The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11092827] +synonym: "male courtship behavior, tapping" RELATED [] +synonym: "male courtship behaviour, tapping" EXACT [] +synonym: "male courtship behaviour, tapping to detect pheromone" RELATED [] +is_a: GO:0008049 ! male courtship behavior + +[Term] +id: GO:0016545 +name: male courtship behavior, veined wing vibration +namespace: biological_process +def: "The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11092827] +synonym: "male courtship behavior, wing vibration" RELATED [] +synonym: "male courtship behaviour, veined wing vibration" EXACT [] +synonym: "male courtship behaviour, wing vibration" RELATED [] +is_a: GO:0048065 ! male courtship behavior, veined wing extension + +[Term] +id: GO:0016546 +name: male courtship behavior, proboscis-mediated licking +namespace: biological_process +def: "The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11092827] +synonym: "male courtship behavior, licking" RELATED [] +synonym: "male courtship behaviour, licking" RELATED [] +synonym: "male courtship behaviour, proboscis-mediated licking" EXACT [] +is_a: GO:0008049 ! male courtship behavior + +[Term] +id: GO:0016550 +name: obsolete insertion or deletion editing +namespace: biological_process +def: "OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription." [PMID:11092837] +comment: This term was made obsolete because it represents two separate processes (insertion and deletion). +synonym: "insertion or deletion editing" EXACT [] +synonym: "insertion/deletion editing" EXACT [] +is_obsolete: true +consider: GO:0070705 +consider: GO:0070706 + +[Term] +id: GO:0016551 +name: obsolete posttranscriptional insertion or deletion editing +namespace: biological_process +def: "OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription." [PMID:11092837] +comment: This term was made obsolete because it represents two separate processes (insertion and deletion). +synonym: "posttranscriptional insertion or deletion editing" EXACT [] +synonym: "posttranscriptional insertion/deletion editing" EXACT [] +is_obsolete: true +consider: GO:0070705 +consider: GO:0070706 + +[Term] +id: GO:0016552 +name: obsolete cotranscriptional insertion or deletion editing +namespace: biological_process +def: "OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription." [PMID:11092837] +comment: This term was made obsolete because it represents two separate processes (insertion and deletion). +synonym: "cotranscriptional insertion or deletion editing" EXACT [] +synonym: "cotranscriptional insertion/deletion editing" EXACT [] +is_obsolete: true +consider: GO:0070705 +consider: GO:0070706 + +[Term] +id: GO:0016553 +name: base conversion or substitution editing +namespace: biological_process +def: "Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s)." [PMID:11092837] +synonym: "base conversion/substitution editing" EXACT [] +is_a: GO:0009451 ! RNA modification + +[Term] +id: GO:0016554 +name: cytidine to uridine editing +namespace: biological_process +def: "The conversion of a cytosine residue to uridine in an RNA molecule by deamination." [PMID:11092837] +is_a: GO:0016553 ! base conversion or substitution editing + +[Term] +id: GO:0016555 +name: uridine to cytidine editing +namespace: biological_process +def: "The conversion of a uridine residue to cytosine in an RNA molecule by amination." [PMID:11092837] +is_a: GO:0016553 ! base conversion or substitution editing + +[Term] +id: GO:0016556 +name: mRNA modification +namespace: biological_process +alt_id: GO:0006381 +def: "The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:curators] +comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'. +synonym: "mRNA editing" NARROW [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0009451 ! RNA modification +is_a: GO:0016071 ! mRNA metabolic process + +[Term] +id: GO:0016557 +name: peroxisome membrane biogenesis +namespace: biological_process +def: "The process in which a peroxisome membrane is synthesized, aggregates, and bonds together." [GOC:mah] +is_a: GO:0044091 ! membrane biogenesis +relationship: part_of GO:0007031 ! peroxisome organization + +[Term] +id: GO:0016558 +name: protein import into peroxisome matrix +namespace: biological_process +def: "The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix." [ISBN:0716731363, PMID:11687502, PMID:11988772] +synonym: "peroxisome matrix protein import" EXACT [] +synonym: "protein transport to peroxisome matrix" EXACT [] +is_a: GO:0006625 ! protein targeting to peroxisome +is_a: GO:0015919 ! peroxisomal membrane transport +is_a: GO:0044743 ! protein transmembrane import into intracellular organelle +is_a: GO:0065002 ! intracellular protein transmembrane transport + +[Term] +id: GO:0016559 +name: peroxisome fission +namespace: biological_process +def: "The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments." [GOC:mah, PMID:11687502, PMID:14754507] +synonym: "peroxisome division" EXACT [] +synonym: "peroxisome proliferation" EXACT [] +is_a: GO:0048285 ! organelle fission +relationship: part_of GO:0007031 ! peroxisome organization + +[Term] +id: GO:0016560 +name: protein import into peroxisome matrix, docking +namespace: biological_process +def: "The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane." [PMID:11687502, PMID:11988772, PMID:14754507] +synonym: "peroxisome matrix protein import, docking" EXACT [] +synonym: "peroxisome receptor docking" RELATED [] +synonym: "protein docking during peroxisome matrix protein import" EXACT [] +synonym: "protein docking during protein import into peroxisome matrix" EXACT [] +synonym: "protein docking during protein transport into peroxisome matrix" EXACT [] +synonym: "protein transport into peroxisome matrix, docking" EXACT [] +is_a: GO:0008104 ! protein localization +relationship: part_of GO:0016558 ! protein import into peroxisome matrix + +[Term] +id: GO:0016561 +name: protein import into peroxisome matrix, translocation +namespace: biological_process +def: "The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation." [PMID:11687502] +synonym: "peroxisome matrix protein import, translocation" EXACT [] +synonym: "peroxisome receptor translocation" RELATED [] +synonym: "protein translocation during peroxisome matrix protein import" EXACT [] +synonym: "protein translocation during protein import into peroxisome matrix" EXACT [] +synonym: "protein translocation during protein transport into peroxisome matrix" EXACT [] +synonym: "protein transport into peroxisome matrix, translocation" EXACT [] +is_a: GO:0065002 ! intracellular protein transmembrane transport +relationship: part_of GO:0016558 ! protein import into peroxisome matrix + +[Term] +id: GO:0016562 +name: protein import into peroxisome matrix, receptor recycling +namespace: biological_process +def: "The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol." [PMID:11687502] +synonym: "peroxisome matrix protein import, receptor recycling" EXACT [] +synonym: "peroxisome receptor recycling" RELATED [] +synonym: "protein transport into peroxisome matrix, receptor recycling" EXACT [] +synonym: "PTS receptor recycling" RELATED [] +synonym: "receptor recycling during peroxisome matrix protein import" EXACT [] +synonym: "receptor recycling during protein import into peroxisome matrix" EXACT [] +synonym: "receptor recycling during protein transport into peroxisome matrix" EXACT [] +is_a: GO:0001881 ! receptor recycling +intersection_of: GO:0001881 ! receptor recycling +intersection_of: part_of GO:0016558 ! protein import into peroxisome matrix +relationship: part_of GO:0016558 ! protein import into peroxisome matrix + +[Term] +id: GO:0016563 +name: obsolete transcription activator activity +namespace: molecular_function +alt_id: GO:0003710 +def: "OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription." [GOC:jl, ISBN:0124325653] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "transcription activating factor" NARROW [] +synonym: "transcription activator activity" EXACT [] +synonym: "transcriptional activator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0001228 + +[Term] +id: GO:0016564 +name: obsolete transcription repressor activity +namespace: molecular_function +def: "OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "negative transcriptional regulator activity" EXACT [] +synonym: "transcription repressor activity" EXACT [] +synonym: "transcriptional repressor activity" EXACT [] +is_obsolete: true +consider: GO:0001227 + +[Term] +id: GO:0016565 +name: obsolete general transcriptional repressor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set." [GOC:mah] +comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "general transcriptional repressor activity" EXACT [] +is_obsolete: true +consider: GO:0001217 +consider: GO:0001227 +consider: GO:0045892 + +[Term] +id: GO:0016566 +name: obsolete specific transcriptional repressor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes." [GOC:mah] +comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "specific transcriptional repressor activity" EXACT [] +is_obsolete: true +consider: GO:0001217 +consider: GO:0001227 +consider: GO:0045892 + +[Term] +id: GO:0016567 +name: protein ubiquitination +namespace: biological_process +def: "The process in which one or more ubiquitin groups are added to a protein." [GOC:ai] +synonym: "protein ubiquitinylation" EXACT [] +synonym: "protein ubiquitylation" EXACT [] +is_a: GO:0032446 ! protein modification by small protein conjugation + +[Term] +id: GO:0016569 +name: covalent chromatin modification +namespace: biological_process +def: "The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups." [GOC:mah, GOC:vw] +synonym: "chromatin modification" EXACT [] +is_a: GO:0006325 ! chromatin organization +is_a: GO:0043412 ! macromolecule modification + +[Term] +id: GO:0016570 +name: histone modification +namespace: biological_process +def: "The covalent alteration of one or more amino acid residues within a histone protein." [GOC:krc] +subset: goslim_yeast +xref: Wikipedia:Histone#Histone_modifications_in_chromatin_regulation +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0016569 ! covalent chromatin modification + +[Term] +id: GO:0016571 +name: histone methylation +namespace: biological_process +def: "The modification of histones by addition of methyl groups." [GOC:ai] +xref: Wikipedia:Histone_methylation +is_a: GO:0006479 ! protein methylation +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016572 +name: histone phosphorylation +namespace: biological_process +def: "The modification of histones by addition of phosphate groups." [GOC:ai] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016573 +name: histone acetylation +namespace: biological_process +def: "The modification of a histone by the addition of an acetyl group." [GOC:ai] +is_a: GO:0016570 ! histone modification +is_a: GO:0018393 ! internal peptidyl-lysine acetylation + +[Term] +id: GO:0016574 +name: histone ubiquitination +namespace: biological_process +def: "The modification of histones by addition of ubiquitin groups." [GOC:ai] +synonym: "histone ubiquitinylation" EXACT [] +synonym: "histone ubiquitylation" EXACT [] +is_a: GO:0016567 ! protein ubiquitination +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016575 +name: histone deacetylation +namespace: biological_process +def: "The modification of histones by removal of acetyl groups." [GOC:ai] +is_a: GO:0006476 ! protein deacetylation +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016576 +name: histone dephosphorylation +namespace: biological_process +def: "The modification of histones by removal of phosphate groups." [GOC:ai] +is_a: GO:0006470 ! protein dephosphorylation +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016577 +name: histone demethylation +namespace: biological_process +def: "The modification of histones by removal of methyl groups." [GOC:ai] +is_a: GO:0006482 ! protein demethylation +is_a: GO:0016570 ! histone modification + +[Term] +id: GO:0016578 +name: histone deubiquitination +namespace: biological_process +def: "The modification of histones by removal of ubiquitin groups." [GOC:ai] +synonym: "histone deubiquitinylation" EXACT [] +synonym: "histone deubiquitylation" EXACT [] +is_a: GO:0016570 ! histone modification +is_a: GO:0016579 ! protein deubiquitination + +[Term] +id: GO:0016579 +name: protein deubiquitination +namespace: biological_process +alt_id: GO:0006514 +def: "The removal of one or more ubiquitin groups from a protein." [GOC:ai] +synonym: "deubiquitination" EXACT [] +synonym: "protein deubiquitinylation" EXACT [] +synonym: "protein deubiquitylation" EXACT [] +is_a: GO:0070646 ! protein modification by small protein removal +relationship: has_part GO:0004843 ! thiol-dependent ubiquitin-specific protease activity + +[Term] +id: GO:0016580 +name: Sin3 complex +namespace: cellular_component +def: "A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins." [PMID:10589671, PMID:11743021, PMID:12865422] +is_a: GO:0070822 ! Sin3-type complex + +[Term] +id: GO:0016581 +name: NuRD complex +namespace: cellular_component +def: "An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins." [PMID:10589671, PMID:11743021, PMID:17289569] +synonym: "Mi-2 complex" EXACT [] +synonym: "NRD complex" EXACT [] +synonym: "nucleosome remodeling and histone deacetylation complex" EXACT [] +is_a: GO:0000118 ! histone deacetylase complex +is_a: GO:0017053 ! transcription repressor complex +is_a: GO:0090545 ! CHD-type complex + +[Term] +id: GO:0016582 +name: obsolete non-covalent chromatin modification +namespace: biological_process +def: "OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups." [GOC:jl, GOC:vw] +comment: This term was made obsolete because it was added in error; its usefulness is unclear. +is_obsolete: true + +[Term] +id: GO:0016583 +name: obsolete nucleosome modeling +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it has been replaced by more specific terms. +synonym: "nucleosome modeling" EXACT [] +is_obsolete: true +consider: GO:0006334 + +[Term] +id: GO:0016584 +name: nucleosome positioning +namespace: biological_process +def: "Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GOC:bf, PMID:11447119, PMID:8676389] +synonym: "nucleosome spacing" EXACT [] +is_a: GO:0031497 ! chromatin assembly +is_a: GO:0034728 ! nucleosome organization + +[Term] +id: GO:0016585 +name: obsolete chromatin remodeling complex +namespace: cellular_component +alt_id: GO:0005679 +def: "OBSOLETE. Any complex that mediates dynamic changes in eukaryotic chromatin." [GOC:mah] +comment: This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge. +synonym: "chromatin remodeling complex" EXACT [] +synonym: "chromatin remodelling complex" EXACT [] +synonym: "nucleosome remodeling complex" EXACT [] +is_obsolete: true +consider: GO:0006338 + +[Term] +id: GO:0016586 +name: RSC-type complex +namespace: cellular_component +alt_id: GO:0070604 +def: "A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining." [GOC:bhm, PMID:11937489, PMID:12672490, PMID:15870268, PMID:19355820, PMID:8980231] +synonym: "PBAF complex" EXACT [] +synonym: "Polybromo- and BAF containing complex" EXACT [CORUM:565] +synonym: "SWI/SNF complex B" EXACT [CORUM:565] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14106 xsd:anyURI +created_by: mah +creation_date: 2009-04-29T01:07:26Z + +[Term] +id: GO:0016587 +name: Isw1 complex +namespace: cellular_component +def: "A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure." [GOC:krc, GOC:mah, PMID:15020051, PMID:15284901, PMID:16568949, PMID:21810179] +is_a: GO:0031010 ! ISWI-type complex + +[Term] +id: GO:0016589 +name: NURF complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters." [GOC:bf, GOC:krc, PMID:10779516, PMID:11279013, PMID:15284901, PMID:16568949, PMID:21810179] +synonym: "nucleosome remodeling factor complex" EXACT [] +is_a: GO:0031010 ! ISWI-type complex + +[Term] +id: GO:0016590 +name: ACF complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair." [GOC:bf, GOC:krc, PMID:12192034, PMID:15284901, PMID:16568949, PMID:21810179] +synonym: "ATP-utilizing chromatin assembly and remodeling factor complex" EXACT [] +is_a: GO:0031010 ! ISWI-type complex + +[Term] +id: GO:0016591 +name: RNA polymerase II, holoenzyme +namespace: cellular_component +def: "A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters." [GOC:jl, GOC:krc, PMID:16858867, Wikipedia:Rna_polymerase_ii] +subset: goslim_pir +synonym: "DNA-directed RNA polymerase II, holoenzyme" EXACT [] +is_a: GO:0055029 ! nuclear DNA-directed RNA polymerase complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0016592 +name: mediator complex +namespace: cellular_component +alt_id: GO:0000119 +def: "A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins." [PMID:11454195, PMID:16168358, PMID:17870225] +synonym: "CDK8-containing TRAP/mediator complex" RELATED [] +synonym: "L mediator complex" EXACT [] +synonym: "Srb-mediator complex" EXACT [GOC:mah] +synonym: "TRAP complex" NARROW [] +xref: Wikipedia:Mediator_(coactivator) +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0070847 ! core mediator complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0016593 +name: Cdc73/Paf1 complex +namespace: cellular_component +def: "A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p." [PMID:11884586] +synonym: "Paf1 complex" EXACT [GOC:cjk] +synonym: "Paf1p complex" EXACT [GOC:cjk] +is_a: GO:0008023 ! transcription elongation factor complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0016594 +name: glycine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glycine, aminoethanoic acid." [GOC:ai] +synonym: "aminoacetic acid binding" EXACT [] +synonym: "aminoethanoic acid binding" EXACT [] +synonym: "Gly binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0016597 ! amino acid binding +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0016595 +name: glutamate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid." [GOC:ai] +synonym: "glutamic acid binding" EXACT [] +is_a: GO:0016597 ! amino acid binding + +[Term] +id: GO:0016596 +name: thienylcyclohexylpiperidine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thienylcyclohexylpiperidine." [GOC:jl] +synonym: "TCP binding" BROAD [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0016597 +name: amino acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents." [GOC:ai] +subset: goslim_metagenomics +subset: goslim_pir +is_a: GO:0031406 ! carboxylic acid binding + +[Term] +id: GO:0016598 +name: protein arginylation +namespace: biological_process +alt_id: GO:0019130 +def: "The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway." [PMID:17896865] +synonym: "protein amino acid arginylation" EXACT [] +is_a: GO:0006464 ! cellular protein modification process +relationship: part_of GO:0006511 ! ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0016600 +name: flotillin complex +namespace: cellular_component +def: "A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae." [PMID:17206938, PMID:17600709] +comment: See also the cellular component term 'caveola ; GO:0005901'. +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005901 ! caveola + +[Term] +id: GO:0016601 +name: Rac protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state." [GOC:bf] +synonym: "Rac mediated signal transduction" EXACT [] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0016602 +name: CCAAT-binding factor complex +namespace: cellular_component +def: "A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5." [GOC:bhm, PMID:7828851] +synonym: "CBF complex" RELATED [GOC:bhm] +synonym: "NF-Y transcription factor complex" RELATED [GOC:bhm] +synonym: "nuclear transcription factor Y complex" RELATED [GOC:bhm] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0016603 +name: glutaminyl-peptide cyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3." [EC:2.3.2.5] +synonym: "glutaminyl cyclase activity" EXACT [EC:2.3.2.5] +synonym: "glutaminyl-transfer ribonucleate cyclotransferase activity" EXACT [EC:2.3.2.5] +synonym: "glutaminyl-tRNA cyclotransferase activity" NARROW [EC:2.3.2.5] +synonym: "L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)" EXACT [EC:2.3.2.5] +xref: EC:2.3.2.5 +xref: MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0016604 +name: nuclear body +namespace: cellular_component +def: "Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins." [GOC:ma, PMID:10330182] +xref: NIF_Subcellular:sao505137457 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0016605 +name: PML body +namespace: cellular_component +def: "A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection." [GOC:ma, PMID:10944585] +synonym: "ND10" EXACT [] +synonym: "nuclear dot" RELATED [] +synonym: "PML NB" EXACT [] +synonym: "PML nuclear body" EXACT [] +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0016606 +name: LYSP100-associated nuclear domain +namespace: cellular_component +def: "A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies." [PMID:10921892, PMID:8695863] +synonym: "LANDs" EXACT [PMID:8695863] +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0016607 +name: nuclear speck +namespace: cellular_component +def: "A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy." [http://www.cellnucleus.com/] +synonym: "nuclear speckle" EXACT [] +synonym: "nuclear speckles" EXACT [] +synonym: "speckle domain" NARROW [] +synonym: "speckle focus" RELATED [] +synonym: "splicing speckle" EXACT [] +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0016608 +name: growth hormone-releasing hormone activity +namespace: molecular_function +def: "The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland." [ISBN:0198506732] +synonym: "GHRF activity" EXACT [ISBN:0198506732] +synonym: "GHRH activity" EXACT [ISBN:0198506732] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0016610 +name: nitrogenase complex +namespace: cellular_component +def: "An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen." [EC:1.18.6.1, MetaCyc:CPLX-186, MetaCyc:CPLX-525] +subset: goslim_pir +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0016611 +name: iron-iron nitrogenase complex +namespace: cellular_component +def: "An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen." [EC:1.18.6.1, GOC:jl, PMID:11848850] +comment: Note that it is not established whether the nitrogenase exists in vivo in a specific particle or whether the nitrogenase proteins are bound nonspecifically to the membranes of some cells. +is_a: GO:0016610 ! nitrogenase complex + +[Term] +id: GO:0016612 +name: molybdenum-iron nitrogenase complex +namespace: cellular_component +def: "An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer." [EC:1.18.6.1] +synonym: "molybdenum-iron nitrogenase activity" RELATED [] +is_a: GO:0016610 ! nitrogenase complex + +[Term] +id: GO:0016613 +name: vanadium-iron nitrogenase complex +namespace: cellular_component +def: "An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer." [EC:1.18.6.1, PMID:3474027] +synonym: "vanadium-iron nitrogenase activity" RELATED [] +is_a: GO:0016610 ! nitrogenase complex + +[Term] +id: GO:0016614 +name: oxidoreductase activity, acting on CH-OH group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-OH group of donors, other acceptors" NARROW [] +xref: EC:1.1 +xref: Reactome:R-HSA-1500781 "Fgd1 reactivates F420" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016615 +name: malate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate." [GOC:mah, ISBN:0582227089] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016616 +name: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [EC:1.1.1.-, GOC:ai] +xref: EC:1.1.1 +xref: Reactome:R-HSA-975629 "RDH11 reduces RBP2:atRAL to RBP2:atROL" +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016617 +name: 4-oxoproline reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+." [EC:1.1.1.104] +synonym: "4-hydroxy-L-proline:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.104] +synonym: "hydroxy-L-proline oxidase activity" EXACT [] +synonym: "hydroxyproline oxidase activity" EXACT [EC:1.1.1.104] +xref: EC:1.1.1.104 +xref: MetaCyc:4-OXOPROLINE-REDUCTASE-RXN +xref: RHEA:13601 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016618 +name: hydroxypyruvate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+." [EC:1.1.1.81] +synonym: "beta-hydroxypyruvate reductase activity" EXACT [EC:1.1.1.81] +synonym: "D-glycerate dehydrogenase activity" EXACT [EC:1.1.1.81] +synonym: "D-glycerate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.81] +synonym: "NADH:hydroxypyruvate reductase activity" EXACT [EC:1.1.1.81] +xref: EC:1.1.1.81 +xref: MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN +xref: MetaCyc:RXN0-300 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016620 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.2.1 +xref: Reactome:R-HSA-1222583 "MscR reduces nitrosomycothiol to ammonia" +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0016621 +name: cinnamoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+." [EC:1.2.1.44] +synonym: "cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)" EXACT [EC:1.2.1.44] +synonym: "cinnamoyl CoA reductase activity" EXACT [] +synonym: "cinnamoyl-CoA:NADPH reductase activity" EXACT [EC:1.2.1.44] +synonym: "cinnamoyl-coenzyme A reductase activity" EXACT [EC:1.2.1.44] +synonym: "feruloyl coenzyme A reductase activity" EXACT [EC:1.2.1.44] +synonym: "feruloyl-CoA reductase activity" EXACT [EC:1.2.1.44] +synonym: "ferulyl-CoA reductase activity" EXACT [EC:1.2.1.44] +synonym: "p-hydroxycinnamoyl coenzyme A reductase activity" EXACT [EC:1.2.1.44] +xref: EC:1.2.1.44 +xref: MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN +xref: RHEA:10620 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016622 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] +xref: EC:1.2.2 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0016623 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +xref: EC:1.2.3 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0016624 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide." [GOC:jl] +synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor" EXACT [] +xref: EC:1.2.4 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0016625 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] +synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.2.7 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0016626 +name: obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016903 + +[Term] +id: GO:0016627 +name: oxidoreductase activity, acting on the CH-CH group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors" NARROW [] +xref: EC:1.3 +xref: Reactome:R-HSA-2995334 "COX15 transforms heme O to heme A" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016628 +name: oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.3.1 +xref: Reactome:R-HSA-4419979 "SRD5A3 reduces pPNOL to DCHOL" +xref: Reactome:R-HSA-4755572 "Defective SRD5A3 does not reduce pPNOL to DCHOL" +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016629 +name: 12-oxophytodienoate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH." [EC:1.3.1.42, RHEA:21888] +synonym: "12-oxo-phytodienoate reductase activity" EXACT [] +synonym: "12-oxo-phytodienoic acid reductase activity" EXACT [EC:1.3.1.42] +synonym: "8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity" EXACT [EC:1.3.1.42] +xref: EC:1.3.1.42 +xref: KEGG_REACTION:R03401 +xref: MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN +xref: RHEA:21888 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016630 +name: protochlorophyllide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+." [EC:1.3.1.33] +synonym: "chlorophyllide-a:NADP+ 7,8-oxidoreductase activity" EXACT [EC:1.3.1.33] +synonym: "NADPH-protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] +synonym: "NADPH-protochlorophyllide reductase activity" EXACT [EC:1.3.1.33] +synonym: "NADPH2-protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] +synonym: "protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] +synonym: "protochlorophyllide photooxidoreductase activity" EXACT [EC:1.3.1.33] +xref: EC:1.3.1.33 +xref: MetaCyc:RXN1F-10 +xref: RHEA:11132 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016631 +name: enoyl-[acyl-carrier-protein] reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+." [EC:1.3.1.9, GOC:rb] +synonym: "acyl-ACP dehydrogenase activity" EXACT [EC:1.3.1.9] +synonym: "enoyl-[acyl-carrier protein] reductase activity" EXACT [] +synonym: "enoyl-ACP reductase activity" EXACT [] +synonym: "enoyl-acyl carrier protein reductase" EXACT [] +xref: EC:1.3.1.9 +xref: MetaCyc:1.3.1.10-RXN +xref: MetaCyc:1.3.1.39-RXN +xref: MetaCyc:RXN1G-2527 +xref: MetaCyc:RXN1G-2544 +xref: MetaCyc:RXN1G-3232 +xref: MetaCyc:RXN1G-3256 +xref: MetaCyc:RXN1G-3613 +xref: MetaCyc:RXN1G-3641 +xref: MetaCyc:RXN1G-3667 +xref: MetaCyc:RXN1G-3993 +xref: MetaCyc:RXN1G-4140 +xref: MetaCyc:RXN1G-45 +xref: Wikipedia:Enoyl-acyl_carrier_protein_reductase +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016632 +name: oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] +xref: EC:1.3.2 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016633 +name: galactonolactone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c." [EC:1.3.2.3] +synonym: "GLDase activity" EXACT [EC:1.3.2.3] +synonym: "GLDHase activity" EXACT [EC:1.3.2.3] +synonym: "L-galactono-1,4-lactone dehydrogenase activity" EXACT [] +synonym: "L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.3.2.3] +synonym: "L-galactono-gamma-lactone dehydrogenase activity" EXACT [EC:1.3.2.3] +synonym: "L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.3.2.3] +synonym: "L-galactonolactone dehydrogenase activity" EXACT [EC:1.3.2.3] +xref: EC:1.3.2.3 +xref: MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN +is_a: GO:0016632 ! oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor + +[Term] +id: GO:0016634 +name: oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +xref: EC:1.3.3 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016635 +name: oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound." [GOC:jl] +xref: EC:1.3.5 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016636 +name: oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] +synonym: "oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.3.7 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0016637 +name: obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016627 + +[Term] +id: GO:0016638 +name: oxidoreductase activity, acting on the CH-NH2 group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors" NARROW [] +xref: EC:1.4 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016639 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] +xref: EC:1.4.1 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0016640 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai] +xref: EC:1.4.2 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0016641 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] +xref: EC:1.4.3 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0016642 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor" EXACT [] +xref: EC:1.4.4 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0016643 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.4.7 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0016644 +name: obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016638 + +[Term] +id: GO:0016645 +name: oxidoreductase activity, acting on the CH-NH group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors" NARROW [] +xref: EC:1.5 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016646 +name: oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.5.1 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0016647 +name: oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +xref: EC:1.5.3 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0016648 +name: oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide." [GOC:jl] +synonym: "oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor" EXACT [] +xref: EC:1.5.4 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0016649 +name: oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound." [GOC:jl] +xref: EC:1.5.5 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0016650 +name: obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016645 + +[Term] +id: GO:0016651 +name: oxidoreductase activity, acting on NAD(P)H +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "NAD(P)H dehydrogenase" NARROW [] +synonym: "oxidoreductase activity, acting on NADH or NADPH" RELATED [] +synonym: "oxidoreductase activity, acting on NADH or NADPH, other acceptor" NARROW [] +xref: EC:1.6 +xref: Reactome:R-HSA-109343 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA" +xref: Reactome:R-HSA-8956458 "RNLS:FAD oxidises dh-beta-NAD to NAD+" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016652 +name: oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] +synonym: "oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor" RELATED [] +xref: EC:1.6.1 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0016653 +name: oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein." [GOC:ai] +synonym: "oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor" EXACT [] +synonym: "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor" RELATED [] +xref: EC:1.6.2 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0016655 +name: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule." [GOC:ai] +synonym: "oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor" RELATED [] +xref: EC:1.6.5 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0016656 +name: monodehydroascorbate reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate." [EC:1.6.5.4] +synonym: "AFR" RELATED [EC:1.6.5.4] +synonym: "AFR-reductase activity" EXACT [EC:1.6.5.4] +synonym: "ascorbate free radical reductase activity" EXACT [EC:1.6.5.4] +synonym: "ascorbate free-radical reductase activity" EXACT [EC:1.6.5.4] +synonym: "ascorbic free radical reductase activity" EXACT [EC:1.6.5.4] +synonym: "MDAsA reductase (NADPH)" EXACT [EC:1.6.5.4] +synonym: "MDHA" RELATED [EC:1.6.5.4] +synonym: "monodehydroascorbate reductase activity" EXACT [] +synonym: "NADH-semidehydroascorbate oxidoreductase activity" EXACT [EC:1.6.5.4] +synonym: "NADH:AFR oxidoreductase activity" EXACT [EC:1.6.5.4] +synonym: "NADH:ascorbate radical oxidoreductase activity" EXACT [EC:1.6.5.4] +synonym: "NADH:monodehydroascorbate oxidoreductase activity" EXACT [EC:1.6.5.4] +synonym: "NADH:semidehydroascorbic acid oxidoreductase activity" EXACT [EC:1.6.5.4] +synonym: "SDA reductase activity" EXACT [EC:1.6.5.4] +synonym: "semidehydroascorbate reductase activity" EXACT [EC:1.6.5.4] +xref: EC:1.6.5.4 +xref: MetaCyc:1.6.5.4-RXN +xref: RHEA:14581 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0016657 +name: oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group." [GOC:ai] +synonym: "oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor" RELATED [] +xref: EC:1.6.6 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0016658 +name: obsolete oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it was a grouping term taken from EC that no longer has any functions associated with it. +synonym: "oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor" EXACT [] +is_obsolete: true +consider: GO:0008752 +consider: GO:0042602 + +[Term] +id: GO:0016659 +name: obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on NADH or NADPH, other acceptor" EXACT [] +is_obsolete: true +consider: GO:0016651 + +[Term] +id: GO:0016661 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors" NARROW [] +xref: EC:1.7 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016662 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] +xref: EC:1.7.2 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0016663 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +xref: EC:1.7.3 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0016664 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] +synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.7.7 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0016665 +name: obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016661 + +[Term] +id: GO:0016667 +name: oxidoreductase activity, acting on a sulfur group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on sulfur group of donors, other acceptors" NARROW [] +synonym: "oxidoreductase activity, acting on sulphur group of donors" EXACT [] +xref: EC:1.8 +xref: Reactome:R-HSA-2213240 "Reduction of disulphide bonds in MHC II antigens" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016668 +name: oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor +namespace: molecular_function +alt_id: GO:0016654 +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +synonym: "oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor" RELATED [] +synonym: "oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor" EXACT [] +synonym: "oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor" EXACT [] +synonym: "oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor" EXACT [] +xref: EC:1.8.1 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016669 +name: oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] +synonym: "oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor" EXACT [] +xref: EC:1.8.2 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016670 +name: oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +synonym: "oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor" EXACT [] +xref: EC:1.8.3 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016671 +name: oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide." [GOC:jl] +synonym: "oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor" EXACT [] +xref: EC:1.8.4 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016672 +name: oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound." [GOC:jl] +synonym: "oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor" EXACT [] +xref: EC:1.8.5 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016673 +name: oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] +synonym: "oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.8.7 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0016674 +name: obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on sulfur group of donors, other acceptors" EXACT [] +synonym: "oxidoreductase activity, acting on sulphur group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016667 + +[Term] +id: GO:0016675 +name: oxidoreductase activity, acting on a heme group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on haem group of donors" EXACT [] +synonym: "oxidoreductase activity, acting on heme group of donors, other acceptors" NARROW [] +xref: EC:1.9 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016676 +name: oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +synonym: "oxidoreductase activity, acting on haem group of donors, oxygen as acceptor" EXACT [] +xref: EC:1.9.3 +is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors + +[Term] +id: GO:0016677 +name: oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group." [GOC:jl] +synonym: "oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor" EXACT [] +xref: EC:1.9.6 +is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors + +[Term] +id: GO:0016678 +name: obsolete oxidoreductase activity, acting on heme group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on haem group of donors, other acceptors" EXACT [] +synonym: "oxidoreductase activity, acting on heme group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016675 + +[Term] +id: GO:0016679 +name: oxidoreductase activity, acting on diphenols and related substances as donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors" NARROW [] +xref: EC:1.10 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016680 +name: oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.10.1 +is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors + +[Term] +id: GO:0016681 +name: oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] +xref: EC:1.10.2 +is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors + +[Term] +id: GO:0016682 +name: oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] +synonym: "laccase activity" RELATED [GOC:jh] +xref: EC:1.10.3 +is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors + +[Term] +id: GO:0016683 +name: obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016679 + +[Term] +id: GO:0016684 +name: oxidoreductase activity, acting on peroxide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor." [GOC:ai] +xref: EC:1.11 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016688 +name: L-ascorbate peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O." [EC:1.11.1.11] +synonym: "ascorbate peroxidase activity" EXACT [EC:1.11.1.11] +synonym: "ascorbic acid peroxidase activity" EXACT [EC:1.11.1.11] +synonym: "L-ascorbate:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.11] +synonym: "L-ascorbic acid peroxidase activity" EXACT [EC:1.11.1.11] +synonym: "L-ascorbic acid-specific peroxidase activity" EXACT [EC:1.11.1.11] +xref: EC:1.11.1.11 +xref: MetaCyc:L-ASCORBATE-PEROXIDASE-RXN +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0016689 +name: manganese peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O." [EC:1.11.1.13] +synonym: "Mn(II):hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.13] +synonym: "Mn-dependent (NADH-oxidizing) peroxidase activity" EXACT [EC:1.11.1.13] +synonym: "Mn-dependent peroxidase activity" EXACT [EC:1.11.1.13] +synonym: "peroxidase-M2" RELATED [EC:1.11.1.13] +xref: EC:1.11.1.13 +xref: MetaCyc:MANGANESE-PEROXIDASE-RXN +xref: RHEA:22776 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0016690 +name: diarylpropane peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O." [EC:1.11.1.14] +synonym: "1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.14] +synonym: "diarylpropane oxygenase activity" EXACT [EC:1.11.1.14] +synonym: "diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)" EXACT [EC:1.11.1.14] +synonym: "lignin peroxidase activity" EXACT [EC:1.11.1.14] +synonym: "ligninase activity" EXACT [EC:1.11.1.14] +synonym: "ligninase I activity" NARROW [EC:1.11.1.14] +synonym: "LiP activity" NARROW [EC:1.11.1.14] +xref: EC:1.11.1.14 +xref: MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN +xref: RHEA:30271 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0016691 +name: chloride peroxidase activity +namespace: molecular_function +alt_id: GO:0016955 +alt_id: GO:0016956 +alt_id: GO:0016957 +alt_id: GO:0016958 +def: "Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O." [EC:1.11.1.10] +synonym: "chloride:hydrogen-peroxide oxidoreductase" EXACT [EC:1.11.1.10] +synonym: "chloroperoxidase activity" EXACT [EC:1.11.1.10] +synonym: "cofactor-free chloroperoxidase activity" NARROW [] +synonym: "flavin-haem chloroperoxidase activity" NARROW [] +synonym: "flavin-heme chloroperoxidase activity" NARROW [] +synonym: "haem chloroperoxidase activity" NARROW [] +synonym: "heme chloroperoxidase activity" NARROW [] +synonym: "vanadium chloroperoxidase activity" NARROW [] +xref: EC:1.11.1.10 +xref: MetaCyc:CHLORIDE-PEROXIDASE-RXN +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0016692 +name: NADH peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+)." [EC:1.11.1.1, RHEA:18509] +synonym: "diphosphopyridine nucleotide peroxidase activity" EXACT [EC:1.11.1.1] +synonym: "DPNH peroxidase activity" EXACT [EC:1.11.1.1] +synonym: "NAD peroxidase activity" EXACT [EC:1.11.1.1] +synonym: "NADH-peroxidase activity" EXACT [EC:1.11.1.1] +synonym: "NADH:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.1] +synonym: "nicotinamide adenine dinucleotide peroxidase activity" EXACT [EC:1.11.1.1] +xref: EC:1.11.1.1 +xref: KEGG_REACTION:R00090 +xref: MetaCyc:NADH-PEROXIDASE-RXN +xref: RHEA:18509 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0016694 +name: obsolete bacterial catalase-peroxidase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it represents a bifunctional gene product. +synonym: "bacterial catalase-peroxidase activity" EXACT [] +is_obsolete: true +consider: GO:0004096 +consider: GO:0004601 + +[Term] +id: GO:0016695 +name: oxidoreductase activity, acting on hydrogen as donor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor." [GOC:jl] +synonym: "oxidoreductase activity, acting on hydrogen as donor, other acceptors" NARROW [] +xref: EC:1.12 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016696 +name: oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.12.1 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0016697 +name: oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor +namespace: molecular_function +alt_id: GO:0016698 +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome." [GOC:jl] +xref: EC:1.12.2 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0016699 +name: oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor +namespace: molecular_function +alt_id: GO:0016736 +alt_id: GO:0019110 +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein." [GOC:jl] +synonym: "oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.12.7 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0016700 +name: obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on hydrogen as donor, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016695 + +[Term] +id: GO:0016701 +name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor." [GOC:mah] +synonym: "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous" NARROW [] +synonym: "oxygenase" BROAD [] +xref: EC:1.13 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016702 +name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor." [GOC:mah] +xref: EC:1.13.11 +xref: Reactome:R-HSA-2161775 "ALOX12 oxidises LTA4 to LXA4/B4" +xref: Reactome:R-HSA-2161907 "ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4" +xref: Reactome:R-HSA-2161917 "ALOX5 oxidises 15S-HpETE to LXA4/B4" +xref: Reactome:R-HSA-5164399 "BCO2:Fe2+ cleaves betaC to APO10al and bION" +xref: Reactome:R-HSA-9018880 "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE" +xref: Reactome:R-HSA-9020274 "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA" +xref: Reactome:R-HSA-9026408 "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3" +xref: Reactome:R-HSA-9026918 "Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA" +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0016703 +name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor." [GOC:mah] +xref: EC:1.13.12 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0016704 +name: obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous +namespace: molecular_function +def: "OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous" EXACT [] +is_obsolete: true +consider: GO:0016701 + +[Term] +id: GO:0016705 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor." [GOC:mah] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous" NARROW [] +xref: EC:1.14 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016706 +name: 2-oxoglutarate-dependent dioxygenase activity +namespace: molecular_function +alt_id: GO:0010302 +def: "Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor." [GOC:mah] +synonym: "2-oxoglutarate dioxygenase activity" EXACT [] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" EXACT [] +xref: EC:1.14.11 +xref: Reactome:R-HSA-1234164 "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)" +xref: Reactome:R-HSA-6783455 "TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe)" +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0016707 +name: gibberellin 3-beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2." [EC:1.14.11.15, GOC:kad] +synonym: "(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)" NARROW [EC:1.14.11.15] +synonym: "(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)" NARROW [EC:1.14.11.15] +synonym: "gibberellin 3-beta-hydroxylase activity" EXACT [EC:1.14.11.15] +synonym: "gibberellin 3beta-dioxygenase activity" EXACT [EC:1.14.11.15] +synonym: "gibberellin 3beta-hydroxylase activity" EXACT [EC:1.14.11.15] +xref: EC:1.14.11.15 +xref: MetaCyc:RXN1F-170 +xref: RHEA:10104 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0016708 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor." [GOC:mah] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor" RELATED [] +xref: EC:1.14.12 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0016709 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen" RELATED [] +xref: EC:1.14.13 +xref: Reactome:R-HSA-2162187 "DHB is hydroxylated to DHDB by COQ6" +xref: Reactome:R-HSA-2162194 "COQ9 dimer:COQ7:Fe2+ hydroxylates DMQ10H2 to DeMQ10H2" +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016710 +name: trans-cinnamate 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O." [EC:1.14.14.91] +synonym: "CA4H activity" NARROW [EC:1.14.14.91] +synonym: "cinnamate 4-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamate 4-monooxygenase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamate hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamic 4-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamic acid 4-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamic acid 4-monooxygenase activity" EXACT [EC:1.14.14.91] +synonym: "cinnamic acid p-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "cytochrome P450 cinnamate 4-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "hydroxylase, cinnamate 4-" EXACT [EC:1.14.14.91] +synonym: "oxygenase, cinnamate 4-mono-" EXACT [EC:1.14.14.91] +synonym: "t-cinnamic acid hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "trans-cinnamate 4-hydroxylase activity" EXACT [EC:1.14.14.91] +synonym: "trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.14.91] +synonym: "trans-cinnamic acid 4-hydroxylase activity" EXACT [EC:1.14.14.91] +xref: EC:1.14.14.91 +xref: MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN +xref: RHEA:10608 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0016711 +name: flavonoid 3'-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O." [EC:1.14.14.82] +synonym: "flavonoid 3'-hydroxylase activity" EXACT [b] +synonym: "flavonoid 3-hydroxylase" RELATED [] +synonym: "flavonoid 3-monooxygenase" RELATED [] +synonym: "flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.14.82] +synonym: "NADPH:flavonoid-3'-hydroxylase activity" EXACT [EC:1.14.14.82] +xref: EC:1.14.14.82 +xref: MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN +xref: RHEA:16337 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0016712 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +alt_id: GO:0008402 +alt_id: GO:0050381 +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] +synonym: "aryl hydrocarbon hydroxylase activity" NARROW [EC:1.14.14.1] +synonym: "aryl-4-monooxygenase activity" NARROW [EC:1.14.14.1] +synonym: "cytochrome p450 activity" NARROW [EC:1.14.14.1] +synonym: "cytochrome P450 CYP19" NARROW [] +synonym: "flavoprotein monooxygenase activity" EXACT [EC:1.14.14.1] +synonym: "flavoprotein-linked monooxygenase activity" EXACT [EC:1.14.14.1] +synonym: "microsomal monooxygenase activity" NARROW [EC:1.14.14.1] +synonym: "microsomal P-450" RELATED [EC:1.14.14.1] +synonym: "microsomal p450 activity" NARROW [EC:1.14.14.1] +synonym: "substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)" EXACT [EC:1.14.14.1] +synonym: "unspecific monooxygenase activity" RELATED [] +synonym: "xenobiotic monooxygenase activity" RELATED [EC:1.14.14.1] +xref: EC:1.14.14 +xref: Reactome:R-HSA-211966 "CYP2D6 4-hydroxylates debrisoquine" +xref: UM-BBD_enzymeID:e0551 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016713 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen" EXACT [] +xref: EC:1.14.15 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016714 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] +xref: EC:1.14.16 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016715 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] +xref: EC:1.14.17 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016716 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor." [GOC:mah] +xref: EC:1.14.18 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016717 +name: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water." [GOC:mah] +xref: EC:1.14.19 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016718 +name: obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous +namespace: molecular_function +def: "OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous" EXACT [] +is_obsolete: true +consider: GO:0016705 + +[Term] +id: GO:0016719 +name: carotene 7,8-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O." [EC:1.14.99.30] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "carotene,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.30] +synonym: "zeta-carotene desaturase activity" EXACT [EC:1.14.99.30] +xref: EC:1.14.99.30 +xref: MetaCyc:1.14.99.30-RXN +xref: RHEA:15701 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016720 +name: delta12-fatty acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O." [EC:1.14.99.33, RHEA:23456] +synonym: "crepenynate synthase activity" NARROW [EC:1.14.99.33] +synonym: "D12-fatty acid dehydrogenase activity" EXACT [] +synonym: "delta-12 fatty acid acetylenase activity" EXACT [EC:1.14.99.33] +synonym: "delta12 fatty acid acetylenase activity" EXACT [EC:1.14.99.33] +synonym: "linoleate delta-12-fatty acid acetylenase (desaturase) activity" EXACT [] +synonym: "linoleate delta12-fatty acid acetylenase (desaturase)" EXACT [EC:1.14.99.33] +synonym: "linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)" EXACT [EC:1.14.99.33] +xref: EC:1.14.99.33 +xref: KEGG_REACTION:R05740 +xref: MetaCyc:1.14.99.33-RXN +xref: RHEA:23456 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0016721 +name: oxidoreductase activity, acting on superoxide radicals as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor." [GOC:ai] +xref: EC:1.15 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016722 +name: oxidoreductase activity, oxidizing metal ions +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered." [GOC:mah] +xref: EC:1.16 +xref: Reactome:R-HSA-917805 "CYBRD1:Heme reduces Fe3+ to Fe2+" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016723 +name: oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor." [GOC:mah] +xref: EC:1.16.1 +xref: Reactome:R-HSA-917811 "STEAP3-like proteins reduce Fe3+ to Fe2+" +is_a: GO:0016722 ! oxidoreductase activity, oxidizing metal ions + +[Term] +id: GO:0016724 +name: oxidoreductase activity, oxidizing metal ions, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor." [GOC:mah] +xref: EC:1.16.3 +is_a: GO:0016722 ! oxidoreductase activity, oxidizing metal ions + +[Term] +id: GO:0016725 +name: oxidoreductase activity, acting on CH or CH2 groups +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on CH or CH2 groups, other acceptors" NARROW [] +xref: EC:1.17 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016726 +name: oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] +xref: EC:1.17.1 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0016727 +name: oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] +xref: EC:1.17.3 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0016728 +name: oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group." [GOC:ai] +synonym: "oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor" EXACT [] +xref: EC:1.17.4 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0016729 +name: obsolete oxidoreductase activity, acting on CH2 groups, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on CH2 groups, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016725 + +[Term] +id: GO:0016730 +name: oxidoreductase activity, acting on iron-sulfur proteins as donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on iron-sulphur proteins as donors" EXACT [] +xref: EC:1.18 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016731 +name: oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.18.1 +is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors + +[Term] +id: GO:0016732 +name: oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl] +xref: EC:1.18.6 +is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors + +[Term] +id: GO:0016733 +name: obsolete iron-iron nitrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate." [EC:1.18.6.1] +comment: This term was made obsolete because it represents a cellular component. +synonym: "iron-iron nitrogenase activity" EXACT [] +is_obsolete: true +consider: GO:0016163 +consider: GO:0016611 + +[Term] +id: GO:0016734 +name: obsolete molybdenum-iron nitrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate." [EC:1.18.6.1] +comment: This term was made obsolete because it represents a cellular component. +synonym: "molybdenum-iron nitrogenase activity" EXACT [] +is_obsolete: true +consider: GO:0016163 +consider: GO:0016612 + +[Term] +id: GO:0016735 +name: obsolete vanadium-iron nitrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate." [EC:1.18.6.1] +comment: This term was made obsolete because it represents a cellular component. +synonym: "vanadium-iron nitrogenase activity" EXACT [] +is_obsolete: true +consider: GO:0016163 +consider: GO:0016613 + +[Term] +id: GO:0016737 +name: oxidoreductase activity, acting on reduced flavodoxin as donor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +xref: EC:1.19 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016738 +name: oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl] +xref: EC:1.19.6 +is_a: GO:0016737 ! oxidoreductase activity, acting on reduced flavodoxin as donor + +[Term] +id: GO:0016739 +name: obsolete oxidoreductase activity, acting on other substrates +namespace: molecular_function +def: "OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on other substrates" EXACT [] +is_obsolete: true +consider: GO:0016491 + +[Term] +id: GO:0016740 +name: transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: EC:2 +xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" +xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" +xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" +xref: Reactome:R-HSA-6787403 "GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA" +xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0016741 +name: transferase activity, transferring one-carbon groups +namespace: molecular_function +def: "Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +xref: EC:2.1 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016742 +name: hydroxymethyl-, formyl- and related transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor)." [EC:2.1.2, GOC:mah] +xref: EC:2.1.2 +is_a: GO:0016741 ! transferase activity, transferring one-carbon groups + +[Term] +id: GO:0016743 +name: carboxyl- or carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "carboxyl- and carbamoyltransferase activity" EXACT [] +xref: EC:2.1.3 +is_a: GO:0016741 ! transferase activity, transferring one-carbon groups + +[Term] +id: GO:0016744 +name: transferase activity, transferring aldehyde or ketonic groups +namespace: molecular_function +alt_id: GO:0016745 +def: "Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +synonym: "transketolase or transaldolase activity" EXACT [] +xref: EC:2.2 +xref: EC:2.2.1 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016746 +name: transferase activity, transferring acyl groups +namespace: molecular_function +alt_id: GO:0008415 +def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +synonym: "acyltransferase activity" EXACT [] +xref: EC:2.3 +xref: Reactome:R-HSA-159431 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine" +xref: Reactome:R-HSA-192312 "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate" +xref: Reactome:R-HSA-193491 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate" +xref: Reactome:R-HSA-6792572 "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs" +xref: Reactome:R-HSA-8858298 "HRASLS transfer acyl group from PC to PE to form NAPE" +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016747 +name: transferase activity, transferring acyl groups other than amino-acyl groups +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "transferase activity, transferring groups other than amino-acyl groups" EXACT [EC:2.3.1] +xref: EC:2.3.1 +is_a: GO:0016746 ! transferase activity, transferring acyl groups + +[Term] +id: GO:0016748 +name: succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016749 +name: N-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016410 ! N-acyltransferase activity +is_a: GO:0016748 ! succinyltransferase activity + +[Term] +id: GO:0016750 +name: O-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016748 ! succinyltransferase activity + +[Term] +id: GO:0016751 +name: S-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016417 ! S-acyltransferase activity +is_a: GO:0016748 ! succinyltransferase activity + +[Term] +id: GO:0016752 +name: sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a sinapoyl group to an acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0016753 +name: O-sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016752 ! sinapoyltransferase activity + +[Term] +id: GO:0016754 +name: sinapoylglucose-malate O-sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate." [EC:2.3.1.92, RHEA:12625] +synonym: "1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity" EXACT [EC:2.3.1.92] +synonym: "1-sinapoylglucose-L-malate sinapoyltransferase activity" EXACT [EC:2.3.1.92] +synonym: "sinapoylglucose:malate sinapoyltransferase activity" EXACT [] +xref: EC:2.3.1.92 +xref: KEGG_REACTION:R03323 +xref: MetaCyc:2.3.1.92-RXN +xref: RHEA:12625 +is_a: GO:0016753 ! O-sinapoyltransferase activity + +[Term] +id: GO:0016755 +name: transferase activity, transferring amino-acyl groups +namespace: molecular_function +def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "aminoacyltransferase activity" EXACT [] +xref: EC:2.3.2 +is_a: GO:0016746 ! transferase activity, transferring acyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0016756 +name: glutathione gamma-glutamylcysteinyltransferase activity +namespace: molecular_function +alt_id: GO:0042143 +def: "Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly." [EC:2.3.2.15] +synonym: "gamma-glutamylcysteine dipeptidyl transpeptidase activity" EXACT [EC:2.3.2.15] +synonym: "glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity" EXACT [EC:2.3.2.15] +synonym: "phytochelatin synthase activity" EXACT [EC:2.3.2.15] +xref: EC:2.3.2.15 +xref: MetaCyc:2.3.2.15-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0016757 +name: transferase activity, transferring glycosyl groups +namespace: molecular_function +alt_id: GO:0016932 +def: "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "glycosyltransferase activity" EXACT [] +synonym: "transferase activity, transferring other glycosyl groups" NARROW [] +synonym: "transglycosidase activity" EXACT [] +synonym: "transglycosylase activity" EXACT [] +xref: EC:2.4 +xref: Reactome:R-HSA-5173005 "B3GALTL transfers glucose to O-fucosyl-proteins" +xref: Reactome:R-HSA-6785565 "Defective B3GALTL does not transfer glucose to O-fucosyl-proteins" +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016758 +name: transferase activity, transferring hexosyl groups +namespace: molecular_function +def: "Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "hexosyltransferase activity" EXACT [] +xref: EC:2.4.1 +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups + +[Term] +id: GO:0016759 +name: cellulose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.12, EC:2.4.1.29] +synonym: "cellulose synthetase activity" EXACT [EC:2.4.1.29] +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0016760 +name: cellulose synthase (UDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.12] +synonym: "1,4-beta-D-glucan synthase activity" EXACT [EC:2.4.1.12] +synonym: "1,4-beta-glucan synthase activity" EXACT [EC:2.4.1.12] +synonym: "beta-1,4-glucan synthase activity" EXACT [EC:2.4.1.12] +synonym: "beta-1,4-glucan synthetase activity" EXACT [EC:2.4.1.12] +synonym: "beta-1,4-glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "beta-glucan synthase activity" EXACT [EC:2.4.1.12] +synonym: "glucan synthase activity" EXACT [EC:2.4.1.12] +synonym: "GS-I" RELATED [EC:2.4.1.12] +synonym: "UDP-glucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDP-glucose-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDP-glucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDPglucose-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDPglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] +synonym: "uridine diphosphoglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] +xref: EC:2.4.1.12 +xref: MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN +is_a: GO:0016759 ! cellulose synthase activity +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0016761 +name: cellulose synthase (GDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.29] +synonym: "cellulose synthase (guanosine diphosphate-forming) activity" EXACT [EC:2.4.1.29] +synonym: "GDP-glucose-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.29] +synonym: "GDP-glucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.29] +synonym: "GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.29] +synonym: "GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.29] +synonym: "guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.29] +synonym: "guanosine diphosphoglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.29] +xref: EC:2.4.1.29 +xref: MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN +is_a: GO:0016759 ! cellulose synthase activity + +[Term] +id: GO:0016762 +name: xyloglucan:xyloglucosyl transferase activity +namespace: molecular_function +alt_id: GO:0080039 +def: "Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan." [EC:2.4.1.207, GOC:ask, PMID:1400418, PMID:1554366] +synonym: "endo-xyloglucan transferase activity" EXACT [EC:2.4.1.207] +synonym: "endoxyloglucan transferase activity" EXACT [] +synonym: "xyloglucan endotransglucosylase activity" EXACT [EC:2.4.1.207] +synonym: "xyloglucan:xyloglucan xyloglucanotransferase activity" EXACT [EC:2.4.1.207] +xref: EC:2.4.1.207 +xref: MetaCyc:2.4.1.207-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0016763 +name: transferase activity, transferring pentosyl groups +namespace: molecular_function +def: "Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)." [GOC:jl] +synonym: "pentosyltransferase activity" EXACT [] +xref: EC:2.4.2 +xref: Reactome:R-HSA-112265 "thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP]" +xref: Reactome:R-HSA-112266 "thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP]" +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups + +[Term] +id: GO:0016764 +name: obsolete transferase activity, transferring other glycosyl groups +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor)." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "transferase activity, transferring other glycosyl groups" EXACT [] +is_obsolete: true +consider: GO:0016757 + +[Term] +id: GO:0016765 +name: transferase activity, transferring alkyl or aryl (other than methyl) groups +namespace: molecular_function +alt_id: GO:0016766 +def: "Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +synonym: "transferase activity, transferring alkyl or aryl groups, other than methyl groups" EXACT [] +xref: EC:2.5 +xref: EC:2.5.1 +xref: Reactome:R-HSA-4419978 "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP" +xref: Reactome:R-HSA-4755545 "Defective DHDDS does not elongate E,E-FPP" +xref: Reactome:R-HSA-6782893 "TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe)" +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016767 +name: geranylgeranyl-diphosphate geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate." [EC:2.5.1.32] +synonym: "geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.32] +synonym: "phytoene synthetase activity" EXACT [EC:2.5.1.32] +synonym: "prephytoene-diphosphate synthase activity" EXACT [EC:2.5.1.32] +synonym: "PSase activity" EXACT [EC:2.5.1.32] +xref: EC:2.5.1.32 +xref: MetaCyc:2.5.1.32-RXN +xref: RHEA:22296 +is_a: GO:0004337 ! geranyltranstransferase activity + +[Term] +id: GO:0016768 +name: spermine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine." [EC:2.5.1.22] +synonym: "S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.22] +synonym: "spermidine aminopropyltransferase activity" EXACT [EC:2.5.1.22] +synonym: "spermine synthetase activity" EXACT [EC:2.5.1.22] +xref: EC:2.5.1.22 +xref: MetaCyc:SPERMINE-SYNTHASE-RXN +xref: Reactome:R-HSA-351210 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine" +xref: RHEA:19973 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0016769 +name: transferase activity, transferring nitrogenous groups +namespace: molecular_function +def: "Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +synonym: "transferase activity, transferring other nitrogenous groups" NARROW [] +xref: EC:2.6 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016770 +name: oximinotransaminase activity +namespace: molecular_function +def: "Catalysis of the reversible transfer of an oxime group to an acceptor." [GOC:ai] +xref: EC:2.6.3 +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups + +[Term] +id: GO:0016771 +name: obsolete transferase activity, transferring other nitrogenous groups +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor)." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "transferase activity, transferring other nitrogenous groups" EXACT [] +is_obsolete: true +consider: GO:0016769 + +[Term] +id: GO:0016772 +name: transferase activity, transferring phosphorus-containing groups +namespace: molecular_function +def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. +subset: goslim_chembl +xref: EC:2.7 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016773 +name: phosphotransferase activity, alcohol group as acceptor +namespace: molecular_function +def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl] +subset: goslim_drosophila +xref: EC:2.7.1 +xref: Reactome:R-HSA-2161193 "abacavir + AMP => abacavir monophosphate + adenosine" +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016774 +name: phosphotransferase activity, carboxyl group as acceptor +namespace: molecular_function +def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor)." [GOC:jl] +xref: EC:2.7.2 +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016775 +name: phosphotransferase activity, nitrogenous group as acceptor +namespace: molecular_function +def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)." [GOC:jl] +xref: EC:2.7.3 +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016776 +name: phosphotransferase activity, phosphate group as acceptor +namespace: molecular_function +def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor)." [GOC:jl] +xref: EC:2.7.4 +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016778 +name: diphosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor)." [GOC:jl, PMID:1651917] +xref: EC:2.7.6 +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016779 +name: nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a nucleotidyl group to a reactant." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_yeast +xref: EC:2.7.7 +xref: Reactome:R-HSA-6782434 "THG1L transfers GMP to 5' end of tRNA(His)" +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016780 +name: phosphotransferase activity, for other substituted phosphate groups +namespace: molecular_function +def: "Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor)." [GOC:jl] +xref: EC:2.7.8 +xref: Reactome:R-HSA-162742 "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI" +xref: Reactome:R-HSA-163069 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol" +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016781 +name: phosphotransferase activity, paired acceptors +namespace: molecular_function +def: "Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors." [GOC:jl] +xref: EC:2.7.9 +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups + +[Term] +id: GO:0016782 +name: transferase activity, transferring sulfur-containing groups +namespace: molecular_function +def: "Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +synonym: "transferase activity, transferring sulphur-containing groups" EXACT [] +xref: EC:2.8 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016783 +name: sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor)." [GOC:ai, ISBN:0721662544] +synonym: "sulphurtransferase activity" EXACT [] +synonym: "tRNA sulfurtransferase activity" NARROW [GOC:mah] +xref: EC:2.8.1 +xref: Reactome:R-HSA-1614618 "Persulfide sulfur is transferred onto sulfite" +xref: Reactome:R-HSA-6782264 "CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs" +xref: Reactome:R-HSA-947538 "Transfer of sulfur from MOCS3-S-S onto MOCS2A" +is_a: GO:0016782 ! transferase activity, transferring sulfur-containing groups + +[Term] +id: GO:0016784 +name: 3-mercaptopyruvate sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate." [EC:2.8.1.2] +synonym: "3-mercaptopyruvate sulphurtransferase activity" EXACT [] +synonym: "3-mercaptopyruvate:cyanide sulfurtransferase activity" EXACT [EC:2.8.1.2] +synonym: "beta-mercaptopyruvate sulfurtransferase activity" EXACT [EC:2.8.1.2] +synonym: "mercaptopyruvate sulfurtransferase activity" EXACT [] +xref: EC:2.8.1.2 +xref: MetaCyc:MERCAPYSTRANS-RXN +xref: Reactome:R-HSA-9012721 "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR" +xref: Reactome:R-HSA-9013471 "MPST transfers sulfur from 3MPYR to HCN to form HSCN" +xref: Reactome:R-HSA-9013533 "MPST transfers sulfur from sulfanegen to HCN to form HSCN" +xref: Reactome:R-HSA-9034756 "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST" +xref: RHEA:21740 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0016785 +name: transferase activity, transferring selenium-containing groups +namespace: molecular_function +alt_id: GO:0016786 +def: "Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] +synonym: "selenotransferase activity" EXACT [] +xref: EC:2.9 +xref: EC:2.9.1 +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0016787 +name: hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +xref: EC:3 +xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes" +xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation" +xref: Reactome:R-HSA-5694583 "ABHD4 hydrolyses NAPE" +xref: Reactome:R-HSA-5695964 "ABHD14B hydrolyses PNPB" +xref: Reactome:R-HSA-6786190 "CMBL hydrolyses OM to OLMS" +xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP" +xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP" +xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate" +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0016788 +name: hydrolase activity, acting on ester bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] +subset: goslim_chembl +synonym: "esterase activity" EXACT [] +xref: EC:3.1 +xref: Reactome:R-HSA-162729 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid" +xref: Reactome:R-HSA-9023617 "Butyrylcholinesterase hydrolyzes acyl Ghrelin" +xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin" +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016790 +name: thiolester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A." [EC:3.1.2] +synonym: "thiolesterase activity" EXACT [] +xref: EC:3.1.2 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0016791 +name: phosphatase activity +namespace: molecular_function +alt_id: GO:0003869 +alt_id: GO:0016302 +def: "Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [EC:3.1.3, GOC:curators, GOC:pg] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_yeast +synonym: "4-nitrophenylphosphatase activity" NARROW [] +synonym: "4-nitrophenylphosphate phosphohydrolase activity" NARROW [EC:3.1.3.41] +synonym: "ecto-p-nitrophenyl phosphatase activity" NARROW [EC:3.1.3.41] +synonym: "K-pNPPase activity" NARROW [EC:3.1.3.41] +synonym: "nitrophenyl phosphatase activity" NARROW [EC:3.1.3.41] +synonym: "NPPase activity" NARROW [EC:3.1.3.41] +synonym: "p-nitrophenylphosphatase activity" NARROW [EC:3.1.3.41] +synonym: "p-nitrophenylphosphate phosphohydrolase activity" NARROW [EC:3.1.3.41] +synonym: "para-nitrophenyl phosphatase activity" NARROW [EC:3.1.3.41] +synonym: "phosphatase" RELATED [] +synonym: "phosphoric monoester hydrolase activity" EXACT [] +synonym: "PNPPase activity" NARROW [EC:3.1.3.41] +xref: EC:3.1.3 +xref: MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN +xref: Reactome:R-HSA-4419986 "Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL" +xref: RHEA:21664 +is_a: GO:0042578 ! phosphoric ester hydrolase activity +relationship: part_of GO:0016311 ! dephosphorylation + +[Term] +id: GO:0016793 +name: triphosphoric monoester hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group." [GOC:ai] +xref: EC:3.1.5 +xref: Reactome:R-HSA-8866601 "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate" +is_a: GO:0042578 ! phosphoric ester hydrolase activity + +[Term] +id: GO:0016794 +name: diphosphoric monoester hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group." [GOC:ai] +xref: EC:3.1.7 +is_a: GO:0042578 ! phosphoric ester hydrolase activity + +[Term] +id: GO:0016795 +name: phosphoric triester hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a phosphoric triester." [EC:3.1.8, GOC:curators] +xref: EC:3.1.8 +is_a: GO:0042578 ! phosphoric ester hydrolase activity + +[Term] +id: GO:0016796 +name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:mah] +comment: Note that this activity can catalyze cleavage of DNA or RNA. +synonym: "exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters" EXACT [] +xref: EC:3.1.15 +is_a: GO:0004527 ! exonuclease activity + +[Term] +id: GO:0016797 +name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters." [GOC:mah] +comment: Note that this activity can catalyze cleavage of DNA or RNA. +xref: EC:3.1.16 +is_a: GO:0004527 ! exonuclease activity + +[Term] +id: GO:0016798 +name: hydrolase activity, acting on glycosyl bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any glycosyl bond." [GOC:jl] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "glycosidase activity" EXACT [] +synonym: "glycosylase" NARROW [] +synonym: "N-glycosylase" NARROW [] +xref: EC:3.2 +xref: Reactome:R-HSA-1793176 "DS is cleaved from its proteoglycan" +xref: Reactome:R-HSA-2065233 "CS is cleaved from its proteoglycan" +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016799 +name: hydrolase activity, hydrolyzing N-glycosyl compounds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any N-glycosyl bond." [GOC:jl] +xref: EC:3.2.2 +is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds + +[Term] +id: GO:0016801 +name: hydrolase activity, acting on ether bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively." [GOC:ai, GOC:jl] +xref: EC:3.3 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016802 +name: trialkylsulfonium hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a thioether bond, -S-." [EC:3.3.1.-, GOC:ai] +synonym: "thioether hydrolase activity" EXACT [] +synonym: "trialkylsulphonium hydrolase activity" EXACT [] +xref: EC:3.3.1 +is_a: GO:0016801 ! hydrolase activity, acting on ether bonds + +[Term] +id: GO:0016803 +name: ether hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an ether bond, -O-." [EC:3.3.2.-, GOC:ai] +xref: EC:3.3.2 +xref: Reactome:R-HSA-8874435 "THEM86B hydrolyses PMCHO, PMETAM" +is_a: GO:0016801 ! hydrolase activity, acting on ether bonds + +[Term] +id: GO:0016804 +name: obsolete prolyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide." [EC:3.4.11.5] +comment: This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined. +synonym: "cytosol aminopeptidase V" RELATED [EC:3.4.11.5] +synonym: "Pro-X aminopeptidase activity" EXACT [EC:3.4.11.5] +synonym: "proline aminopeptidase" BROAD [EC:3.4.11.5] +synonym: "proline iminopeptidase activity" EXACT [] +synonym: "prolyl aminopeptidase activity" EXACT [] +xref: EC:3.4.11.5 +xref: MetaCyc:3.4.11.5-RXN +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0016805 +name: dipeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a dipeptide." [PMID:19879002] +xref: EC:3.4.13 +xref: Reactome:R-HSA-266012 "LTD4 is converted to LTE4 by DPEP1/2" +xref: Reactome:R-HSA-5433067 "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG" +xref: Reactome:R-HSA-5693783 "NAALADases hydrolyse NAAG" +xref: Reactome:R-HSA-9026771 "DPEP hydroyses MCTR2 to MCTR3" +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0016806 +name: obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain." [GOC:ai] +comment: This term was made obsolete because it represents two activities. +synonym: "dipeptidyl-peptidase and tripeptidyl-peptidase activity" EXACT [] +xref: EC:3.4.14 +is_obsolete: true + +[Term] +id: GO:0016807 +name: cysteine-type carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of C-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +xref: EC:3.4.18 +xref: MetaCyc:3.4.18.1-RXN +is_a: GO:0004180 ! carboxypeptidase activity +is_a: GO:0070004 ! cysteine-type exopeptidase activity + +[Term] +id: GO:0016808 +name: obsolete proprotein convertase activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "proprotein convertase activity" EXACT [] +xref: EC:3.4.21 +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0016810 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds." [GOC:jl] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +synonym: "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds" NARROW [] +xref: EC:3.5 +xref: Reactome:R-HSA-6803753 "NAAA hydrolyses NAEs to FAs and ethanolamine" +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016811 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide." [GOC:ai] +xref: EC:3.5.1 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0016812 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide." [GOC:ai] +xref: EC:3.5.2 +xref: Reactome:R-HSA-70906 "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+" +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0016813 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2." [ISBN:0198506732] +xref: EC:3.5.3 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0016814 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2." [ISBN:0198506732] +xref: EC:3.5.4 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0016815 +name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN." [GOC:curators] +xref: EC:3.5.5 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0016816 +name: obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds" EXACT [] +is_obsolete: true +consider: GO:0016810 + +[Term] +id: GO:0016817 +name: hydrolase activity, acting on acid anhydrides +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid anhydride." [GOC:jl] +synonym: "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement" NARROW [] +xref: EC:3.6 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016818 +name: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." [GOC:jl] +xref: EC:3.6.1 +is_a: GO:0016817 ! hydrolase activity, acting on acid anhydrides + +[Term] +id: GO:0016819 +name: hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-." [GOC:ai] +synonym: "hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides" EXACT [] +xref: EC:3.6.2 +is_a: GO:0016817 ! hydrolase activity, acting on acid anhydrides + +[Term] +id: GO:0016821 +name: obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it incorporates process information. +synonym: "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement" EXACT [] +is_obsolete: true +replaced_by: GO:0016817 + +[Term] +id: GO:0016822 +name: hydrolase activity, acting on acid carbon-carbon bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid carbon-carbon bond." [GOC:jl] +xref: EC:3.7 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016823 +name: hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group." [GOC:ai] +xref: EC:3.7.1 +is_a: GO:0016822 ! hydrolase activity, acting on acid carbon-carbon bonds + +[Term] +id: GO:0016824 +name: hydrolase activity, acting on acid halide bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid halide bond." [GOC:jl] +xref: EC:3.8 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016825 +name: hydrolase activity, acting on acid phosphorus-nitrogen bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond." [GOC:jl] +xref: EC:3.9 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016826 +name: hydrolase activity, acting on acid sulfur-nitrogen bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid sulfur-nitrogen bond." [GOC:jl] +synonym: "hydrolase activity, acting on acid sulphur-nitrogen bonds" EXACT [] +xref: EC:3.10 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016827 +name: hydrolase activity, acting on acid carbon-phosphorus bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid carbon-phosphorus bond." [GOC:jl] +xref: EC:3.11 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016828 +name: hydrolase activity, acting on acid sulfur-sulfur bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid sulfur-sulfur bond." [GOC:jl] +synonym: "hydrolase activity, acting on acid sulphur-sulphur bonds" EXACT [] +xref: EC:3.12 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0016829 +name: lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_yeast +synonym: "other lyase activity" NARROW [] +xref: EC:4 +xref: Reactome:R-HSA-5696408 "PHYKPL tetramer hydrolyses 5PHL" +xref: Reactome:R-HSA-6782895 "TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)" +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0016830 +name: carbon-carbon lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:jl] +synonym: "other carbon-carbon lyase activity" NARROW [] +xref: EC:4.1 +xref: Reactome:R-HSA-389611 "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA" +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016831 +name: carboxy-lyase activity +namespace: molecular_function +def: "Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound." [http://www.mercksource.com/] +synonym: "decarboxylase activity" EXACT [] +xref: EC:4.1.1 +xref: Reactome:R-HSA-6787757 "GADL1 decarboxylates acidic AAs" +xref: Reactome:R-HSA-6814165 "GADL1 decarboxylates CSA to HTAU" +xref: Reactome:R-HSA-71223 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2" +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0016832 +name: aldehyde-lyase activity +namespace: molecular_function +alt_id: GO:0016228 +def: "Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone." [http://www.mercksource.com/] +synonym: "aldolase activity" BROAD [] +xref: EC:4.1.2 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0016833 +name: oxo-acid-lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid." [EC:4.1.3, GOC:jl] +synonym: "oxo-acid lyase activity" EXACT [] +synonym: "oxoacid lyase activity" EXACT [] +xref: EC:4.1.3 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0016834 +name: obsolete other carbon-carbon lyase activity +namespace: molecular_function +def: "OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other carbon-carbon lyase activity" EXACT [] +is_obsolete: true +consider: GO:0016830 + +[Term] +id: GO:0016835 +name: carbon-oxygen lyase activity +namespace: molecular_function +def: "Catalysis of the breakage of a carbon-oxygen bond." [EC:4.2.-.-] +synonym: "other carbon-oxygen lyase activity" NARROW [] +xref: EC:4.2 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016836 +name: hydro-lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of water." [EC:4.2.1] +xref: EC:4.2.1 +xref: Reactome:R-HSA-9014627 "SDS dimers:PXLP dehydrate L-Thr to 2AA" +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0016837 +name: carbon-oxygen lyase activity, acting on polysaccharides +namespace: molecular_function +def: "Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide." [EC:4.2.-.-] +xref: EC:4.2.2 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0016838 +name: carbon-oxygen lyase activity, acting on phosphates +namespace: molecular_function +def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate." [EC:4.2.-.-] +xref: EC:4.2.3 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0016839 +name: obsolete other carbon-oxygen lyase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases." [GOC:krc] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other carbon-oxygen lyase activity" EXACT [] +is_obsolete: true +consider: GO:0016835 + +[Term] +id: GO:0016840 +name: carbon-nitrogen lyase activity +namespace: molecular_function +def: "Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-] +synonym: "other carbon-nitrogen lyase activity" NARROW [] +xref: EC:4.3 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016841 +name: ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate." [EC:4.3.-.-, GOC:krc] +xref: EC:4.3.1 +is_a: GO:0016840 ! carbon-nitrogen lyase activity + +[Term] +id: GO:0016842 +name: amidine-lyase activity +namespace: molecular_function +def: "Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate." [EC:4.3.-.-, GOC:krc] +xref: EC:4.3.2 +is_a: GO:0016840 ! carbon-nitrogen lyase activity + +[Term] +id: GO:0016843 +name: amine-lyase activity +namespace: molecular_function +def: "Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate." [EC:4.3.-.-, GOC:krc] +xref: EC:4.3.3 +is_a: GO:0016840 ! carbon-nitrogen lyase activity + +[Term] +id: GO:0016844 +name: strictosidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine." [EC:4.3.3.2, RHEA:15013] +synonym: "3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.2] +synonym: "3-alpha(S)-strictosidine tryptamine-lyase activity" EXACT [EC:4.3.3.2] +synonym: "STR activity" EXACT [EC:4.3.3.2] +synonym: "strictosidine synthetase activity" EXACT [EC:4.3.3.2] +xref: EC:4.3.3.2 +xref: KEGG_REACTION:R03738 +xref: MetaCyc:STRICTOSIDINE-SYNTHASE-RXN +xref: RHEA:15013 +is_a: GO:0016843 ! amine-lyase activity + +[Term] +id: GO:0016845 +name: obsolete other carbon-nitrogen lyase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases." [GOC:krc] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other carbon-nitrogen lyase activity" EXACT [] +is_obsolete: true +consider: GO:0016840 + +[Term] +id: GO:0016846 +name: carbon-sulfur lyase activity +namespace: molecular_function +def: "Catalysis of the elimination of hydrogen sulfide or substituted H2S." [EC:4.4.-.-] +synonym: "carbon-sulphur lyase activity" EXACT [] +xref: EC:4.4 +xref: Reactome:R-HSA-1614567 "Excess homocysteine yields homolanthionine and H2S" +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016847 +name: 1-aminocyclopropane-1-carboxylate synthase activity +namespace: molecular_function +alt_id: GO:0034100 +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+)." [EC:4.4.1.14, RHEA:21744] +comment: Note that this function was formerly EC:4.1.99.4. +synonym: "1-aminocyclopropane-1-carboxylate synthetase activity" EXACT [EC:4.4.1.14] +synonym: "1-aminocyclopropane-1-carboxylic acid synthase activity" EXACT [EC:4.4.1.14] +synonym: "1-aminocyclopropanecarboxylate synthase activity" EXACT [EC:4.4.1.14] +synonym: "ACC synthase activity" EXACT [EC:4.4.1.14] +synonym: "aminocyclopropanecarboxylate synthase activity" EXACT [EC:4.4.1.14] +synonym: "aminocyclopropanecarboxylic acid synthase activity" EXACT [EC:4.4.1.14] +synonym: "L-VG deaminase activity" RELATED [PMID:11470512] +synonym: "L-vinylglycine deaminase activity" RELATED [PMID:11470512] +synonym: "S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)" EXACT [EC:4.4.1.14] +synonym: "S-adenosyl-L-methionine methylthioadenosine-lyase activity" EXACT [EC:4.4.1.14] +xref: EC:4.4.1.14 +xref: KEGG_REACTION:R00179 +xref: MetaCyc:4.4.1.14-RXN +xref: RHEA:21744 +is_a: GO:0016846 ! carbon-sulfur lyase activity +relationship: part_of GO:0042218 ! 1-aminocyclopropane-1-carboxylate biosynthetic process + +[Term] +id: GO:0016848 +name: carbon-halide lyase activity +namespace: molecular_function +def: "Catalysis of the breakage of a bond between carbon and any halogen atom." [GOC:mah] +xref: EC:4.5 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016849 +name: phosphorus-oxygen lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:jl] +xref: EC:4.6 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016850 +name: obsolete other lyase activity +namespace: molecular_function +def: "OBSOLETE. A grouping term for lyases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other lyase activity" EXACT [] +is_obsolete: true +consider: GO:0016829 + +[Term] +id: GO:0016851 +name: magnesium chelatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate." [EC:6.6.1.1, RHEA:13961] +comment: Note that this was EC:4.99.1.1. +synonym: "magnesium-chelatase activity" EXACT [EC:6.6.1.1] +synonym: "magnesium-protoporphyrin chelatase activity" EXACT [EC:6.6.1.1] +synonym: "magnesium-protoporphyrin IX chelatase activity" EXACT [EC:6.6.1.1] +synonym: "Mg-chelatase activity" BROAD [EC:6.6.1.1] +synonym: "Mg-protoporphyrin IX chelatase activity" EXACT [EC:6.6.1.1] +synonym: "Mg-protoporphyrin IX magnesio-lyase activity" EXACT [EC:6.6.1.1] +synonym: "Mg-protoporphyrin IX magnesium-lyase activity" EXACT [EC:6.6.1.1] +synonym: "protoporphyrin IX magnesium-chelatase activity" EXACT [EC:6.6.1.1] +synonym: "protoporphyrin IX Mg-chelatase activity" EXACT [EC:6.6.1.1] +xref: EC:6.6.1.1 +xref: KEGG_REACTION:R03877 +xref: MetaCyc:RXN1F-20 +xref: RHEA:13961 +is_a: GO:0051003 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes + +[Term] +id: GO:0016852 +name: sirohydrochlorin cobaltochelatase activity +namespace: molecular_function +def: "Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+." [EC:4.99.1.3] +synonym: "anaerobic cobalt chelatase activity" EXACT [] +synonym: "CbiK" NARROW [] +synonym: "CbiX" RELATED [EC:4.99.1.3] +synonym: "CbiXS" RELATED [EC:4.99.1.3] +synonym: "cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)" EXACT [EC:4.99.1.3] +synonym: "sirohydrochlorin cobalt-lyase activity" EXACT [EC:4.99.1.3] +xref: EC:4.99.1.3 +xref: MetaCyc:4.99.1.3-RXN +xref: RHEA:15893 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0016853 +name: isomerase activity +namespace: molecular_function +def: "Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5." [ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_yeast +synonym: "other isomerase activity" NARROW [] +xref: EC:5 +xref: Reactome:R-HSA-6787623 "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal" +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0016854 +name: racemase and epimerase activity +namespace: molecular_function +def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule." [GOC:mah, ISBN:0198506732] +comment: Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound. +synonym: "racemase and epimerase activity, acting on other compounds" NARROW [] +xref: EC:5.1 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0016855 +name: racemase and epimerase activity, acting on amino acids and derivatives +namespace: molecular_function +def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid." [GOC:mah] +xref: EC:5.1.1 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0016856 +name: racemase and epimerase activity, acting on hydroxy acids and derivatives +namespace: molecular_function +def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule." [GOC:mah] +xref: EC:5.1.2 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0016857 +name: racemase and epimerase activity, acting on carbohydrates and derivatives +namespace: molecular_function +def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule." [GOC:mah] +xref: EC:5.1.3 +xref: Reactome:R-HSA-6787677 "FUOM isomerises alpha-Fuc to beta-Fuc" +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0016858 +name: obsolete racemase and epimerase activity, acting on other compounds +namespace: molecular_function +def: "OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "racemase and epimerase activity, acting on other compounds" EXACT [] +is_obsolete: true +consider: GO:0016854 + +[Term] +id: GO:0016859 +name: cis-trans isomerase activity +namespace: molecular_function +def: "Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers." [GOC:mah, ISBN:0198506732] +xref: EC:5.2 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0016860 +name: intramolecular oxidoreductase activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears." [EC:5.3.-.-] +synonym: "intramolecular isomerase activity" EXACT [] +synonym: "intramolecular oxidoreductase activity, other intramolecular oxidoreductases" NARROW [] +xref: EC:5.3 +xref: Reactome:R-HSA-109998 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA" +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0016861 +name: intramolecular oxidoreductase activity, interconverting aldoses and ketoses +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears." [GOC:jl] +synonym: "intramolecular isomerase activity, interconverting aldoses and ketoses" EXACT [] +xref: EC:5.3.1 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0016862 +name: intramolecular oxidoreductase activity, interconverting keto- and enol-groups +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears." [GOC:jl] +synonym: "intramolecular isomerase activity, interconverting keto- and enol-groups" EXACT [] +xref: EC:5.3.2 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0016863 +name: intramolecular oxidoreductase activity, transposing C=C bonds +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears." [EC:5.3.3, GOC:mah] +synonym: "intramolecular isomerase activity, transposing C=C bonds" EXACT [] +xref: EC:5.3.3 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0016864 +name: intramolecular oxidoreductase activity, transposing S-S bonds +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears." [EC:5.3.4, GOC:mah] +synonym: "intramolecular isomerase activity, transposing S-S bonds" EXACT [] +xref: EC:5.3.4 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0016865 +name: obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases +namespace: molecular_function +def: "OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "intramolecular isomerase activity, other intramolecular oxidoreductases" EXACT [] +synonym: "intramolecular oxidoreductase activity, other intramolecular oxidoreductases" EXACT [] +is_obsolete: true +consider: GO:0016860 + +[Term] +id: GO:0016866 +name: intramolecular transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a functional group from one position to another within a single molecule." [GOC:mah] +synonym: "intramolecular transferase activity, transferring other groups" NARROW [] +synonym: "mutase activity" EXACT [] +xref: EC:5.4 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0016867 +name: intramolecular transferase activity, transferring acyl groups +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group from one position to another within a single molecule." [GOC:mah] +xref: EC:5.4.1 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0016868 +name: intramolecular transferase activity, phosphotransferases +namespace: molecular_function +alt_id: GO:0016777 +def: "Catalysis of the transfer of a phosphate group from one position to another within a single molecule." [GOC:mah] +synonym: "phosphomutase activity" EXACT [] +synonym: "phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers" EXACT [] +xref: EC:5.4.2 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0016869 +name: intramolecular transferase activity, transferring amino groups +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from one position to another within a single molecule." [GOC:mah] +xref: EC:5.4.3 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0016870 +name: obsolete intramolecular transferase activity, transferring other groups +namespace: molecular_function +def: "OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "intramolecular transferase activity, transferring other groups" EXACT [] +is_obsolete: true +consider: GO:0016866 + +[Term] +id: GO:0016871 +name: cycloartenol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol." [EC:5.4.99.8, RHEA:21308] +synonym: "(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)" EXACT [EC:5.4.99.8] +synonym: "2,3-epoxysqualene cycloartenol-cyclase activity" EXACT [EC:5.4.99.8] +synonym: "2,3-epoxysqualene--cycloartenol cyclase activity" EXACT [EC:5.4.99.8] +synonym: "2,3-oxidosqualene-cycloartenol cyclase activity" EXACT [EC:5.4.99.8] +synonym: "oxidosqualene:cycloartenol cyclase activity" EXACT [PMID:18033581] +synonym: "squalene-2,3-epoxide-cycloartenol cyclase activity" EXACT [EC:5.4.99.8] +xref: EC:5.4.99.8 +xref: KEGG_REACTION:R03200 +xref: MetaCyc:CYCLOARTENOL-SYNTHASE-RXN +xref: RHEA:21308 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0016872 +name: intramolecular lyase activity +namespace: molecular_function +def: "The catalysis of certain rearrangements of a molecule to break or form a ring." [GOC:jl, http://www.mercksource.com/] +xref: EC:5.5.1 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0016873 +name: obsolete other isomerase activity +namespace: molecular_function +def: "OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other isomerase activity" EXACT [] +is_obsolete: true +consider: GO:0016853 + +[Term] +id: GO:0016874 +name: ligase activity +namespace: molecular_function +def: "Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6, GOC:mah] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_yeast +synonym: "synthetase activity" EXACT [GOC:jh2] +xref: EC:6 +is_a: GO:0003824 ! catalytic activity + +[Term] +id: GO:0016875 +name: ligase activity, forming carbon-oxygen bonds +namespace: molecular_function +def: "Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.1, GOC:mah] +xref: EC:6.1 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0016877 +name: ligase activity, forming carbon-sulfur bonds +namespace: molecular_function +def: "Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.2, GOC:mah] +synonym: "ligase activity, forming carbon-sulphur bonds" EXACT [] +xref: EC:6.2 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0016878 +name: acid-thiol ligase activity +namespace: molecular_function +def: "Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.2.1, GOC:mah] +xref: EC:6.2.1 +is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds + +[Term] +id: GO:0016879 +name: ligase activity, forming carbon-nitrogen bonds +namespace: molecular_function +def: "Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [GOC:mah] +synonym: "other carbon-nitrogen ligase activity" NARROW [] +xref: EC:6.3 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0016880 +name: acid-ammonia (or amide) ligase activity +namespace: molecular_function +def: "Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [GOC:jl, GOC:mah] +synonym: "amide synthase activity" EXACT [] +xref: EC:6.3.1 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0016881 +name: acid-amino acid ligase activity +namespace: molecular_function +def: "Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [GOC:jl, GOC:mah] +synonym: "peptide synthase activity" EXACT [] +xref: EC:6.3.2 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0016882 +name: cyclo-ligase activity +namespace: molecular_function +def: "Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.3.3.1, EC:6.3.3.2, EC:6.3.3.4, GOC:jl, GOC:mah] +xref: EC:6.3.3 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0016883 +name: obsolete other carbon-nitrogen ligase activity +namespace: molecular_function +def: "OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "other carbon-nitrogen ligase activity" EXACT [] +is_obsolete: true +consider: GO:0016879 + +[Term] +id: GO:0016884 +name: carbon-nitrogen ligase activity, with glutamine as amido-N-donor +namespace: molecular_function +alt_id: GO:0016003 +def: "Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen." [PMID:12360532] +xref: EC:6.3.5 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16422 xsd:anyURI + +[Term] +id: GO:0016885 +name: ligase activity, forming carbon-carbon bonds +namespace: molecular_function +def: "Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.4, GOC:jl, GOC:mah] +xref: EC:6.4 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0016886 +name: ligase activity, forming phosphoric ester bonds +namespace: molecular_function +def: "Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.5, GOC:mah] +xref: EC:6.5 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0016887 +name: ATPase activity +namespace: molecular_function +alt_id: GO:0004002 +alt_id: GO:0042623 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction." [EC:3.6.1.3, GOC:jl] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "(Ca2+ + Mg2+)-ATPase" NARROW [EC:3.6.1.3] +synonym: "adenosine 5'-triphosphatase activity" EXACT [EC:3.6.1.3] +synonym: "adenosine triphosphatase activity" EXACT [EC:3.6.1.3] +synonym: "adenosinetriphosphatase activity" EXACT [] +synonym: "ATP hydrolase activity" EXACT [EC:3.6.1.3] +synonym: "ATP monophosphatase activity" EXACT [EC:3.6.1.3] +synonym: "ATP phosphohydrolase (polypeptide-unfolding)" NARROW [EC:3.6.4.9] +synonym: "ATP phosphohydrolase activity" EXACT [] +synonym: "ATPase activity, coupled" RELATED [] +synonym: "chaperonin" RELATED [EC:3.6.4.9] +synonym: "chaperonin ATPase activity" RELATED [] +synonym: "complex V (mitochondrial electron transport)" NARROW [EC:3.6.1.3] +synonym: "HCO3--ATPase" NARROW [EC:3.6.1.3] +synonym: "non-chaperonin molecular chaperone ATPase activity" RELATED [] +synonym: "nucleoplasmin ATPase activity" RELATED [] +synonym: "peroxisome-assembly ATPase activity" RELATED [] +synonym: "SV40 T-antigen" RELATED [EC:3.6.1.3] +synonym: "vesicle-fusing ATPase activity" RELATED [EC:3.6.4.6] +xref: EC:3.6.1.3 +xref: MetaCyc:ADENOSINETRIPHOSPHATASE-RXN +xref: Reactome:R-HSA-159101 "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)" +xref: Reactome:R-HSA-3371422 "ATP hydrolysis by HSP70" +xref: Reactome:R-HSA-416985 "Trafficking of GluR2-containing AMPA receptors to synapse" +xref: Reactome:R-HSA-5618093 "ATP hydrolysis by HSP90" +xref: Reactome:R-HSA-5654989 "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA" +xref: Reactome:R-HSA-5694425 "NSF ATPase activity dissociates cis-SNARE" +xref: Reactome:R-HSA-6809015 "NSF ATPase activity dissociates cis-SNARE at cis-Golgi" +xref: Reactome:R-HSA-6811422 "NSF ATPase activity dissociates cis-SNARE at the ER" +xref: Reactome:R-HSA-6814670 "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation" +xref: Reactome:R-HSA-6814678 "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN" +xref: Reactome:R-HSA-6814683 "NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN" +xref: Reactome:R-HSA-72139 "Formation of the active Spliceosomal C (B*) complex" +xref: Reactome:R-HSA-8847638 "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane" +xref: Reactome:R-HSA-8868658 "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating" +xref: Reactome:R-HSA-8939203 "HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex" +xref: Reactome:R-HSA-9038161 "Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG" +xref: Reactome:R-HSA-917693 "ESCRT Disassembly" +xref: Reactome:R-HSA-9609860 "Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP" +xref: RHEA:13065 +is_a: GO:0017111 ! nucleoside-triphosphatase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19078 xsd:anyURI + +[Term] +id: GO:0016888 +name: endodeoxyribonuclease activity, producing 5'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:ai] +synonym: "endodeoxyribonuclease activity, producing 5' phosphomonoesters" EXACT [] +xref: EC:3.1.21 +xref: Reactome:R-HSA-912368 "SPO11 hydrolyzes DNA forming double-strand breaks" +is_a: GO:0004520 ! endodeoxyribonuclease activity +is_a: GO:0016893 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters + +[Term] +id: GO:0016889 +name: endodeoxyribonuclease activity, producing 3'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:ai] +synonym: "endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters" EXACT [] +xref: EC:3.1.22 +is_a: GO:0004520 ! endodeoxyribonuclease activity +is_a: GO:0016894 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters + +[Term] +id: GO:0016890 +name: site-specific endodeoxyribonuclease activity, specific for altered base +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks." [GOC:jl] +xref: EC:3.1.25 +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0016891 +name: endoribonuclease activity, producing 5'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:ai] +xref: EC:3.1.26 +is_a: GO:0004521 ! endoribonuclease activity +is_a: GO:0016893 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters + +[Term] +id: GO:0016892 +name: endoribonuclease activity, producing 3'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:ai] +synonym: "endoribonuclease activity, producing other than 5'-phosphomonoesters" EXACT [] +xref: EC:3.1.27 +is_a: GO:0004521 ! endoribonuclease activity +is_a: GO:0016894 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters + +[Term] +id: GO:0016893 +name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:mah] +comment: Note that this activity can catalyze cleavage of DNA or RNA. +synonym: "5'-endonuclease activity" EXACT [] +synonym: "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters" RELATED [] +xref: EC:3.1.30 +is_a: GO:0004519 ! endonuclease activity + +[Term] +id: GO:0016894 +name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:mah] +comment: Note that this activity can catalyze cleavage of DNA or RNA. +synonym: "3'-endonuclease activity" EXACT [] +synonym: "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters" RELATED [] +xref: EC:3.1.31 +is_a: GO:0004519 ! endonuclease activity + +[Term] +id: GO:0016895 +name: exodeoxyribonuclease activity, producing 5'-phosphomonoesters +namespace: molecular_function +alt_id: GO:0008858 +def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:ai] +synonym: "exodeoxyribonuclease activity, producing 5' phosphomonoesters" EXACT [] +synonym: "exonuclease VIII activity" NARROW [] +xref: EC:3.1.11 +is_a: GO:0004529 ! exodeoxyribonuclease activity +is_a: GO:0016796 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters + +[Term] +id: GO:0016896 +name: exoribonuclease activity, producing 5'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:ai] +synonym: "exoribonuclease activity, producing 5' phosphomonoesters" EXACT [] +xref: EC:3.1.13 +xref: Reactome:R-HSA-429860 "DCP1-DCP2 complex decaps mRNA" +is_a: GO:0004532 ! exoribonuclease activity +is_a: GO:0016796 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters + +[Term] +id: GO:0016897 +name: exoribonuclease activity, producing 3'-phosphomonoesters +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters." [GOC:ai] +xref: EC:3.1.14 +is_a: GO:0004532 ! exoribonuclease activity +is_a: GO:0016797 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters + +[Term] +id: GO:0016898 +name: oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai] +xref: EC:1.1.2 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016899 +name: oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] +xref: EC:1.1.3 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016900 +name: oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule." [GOC:ai] +synonym: "oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor" EXACT [] +xref: EC:1.1.4 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016901 +name: oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule." [GOC:ai] +xref: EC:1.1.5 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0016902 +name: obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on the CH-OH group of donors, other acceptors" EXACT [] +is_obsolete: true +consider: GO:0016614 + +[Term] +id: GO:0016903 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] +synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors" NARROW [] +xref: EC:1.2 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0016905 +name: myosin heavy chain kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate." [EC:2.7.11.7] +synonym: "ATP:myosin heavy-chain O-phosphotransferase activity" EXACT [EC:2.7.11.7] +synonym: "ATP:myosin-heavy-chain O-phosphotransferase activity" EXACT [EC:2.7.11.7] +synonym: "calmodulin-dependent myosin heavy chain kinase activity" EXACT [EC:2.7.11.7] +synonym: "MHCK" RELATED [EC:2.7.11.7] +synonym: "MIHC kinase activity" EXACT [EC:2.7.11.7] +synonym: "myosin heavy chain kinase A activity" EXACT [EC:2.7.11.7] +synonym: "myosin heavy-chain kinase activity" EXACT [EC:2.7.11.7] +synonym: "myosin I heavy chain kinase activity" NARROW [EC:2.7.11.7] +synonym: "myosin I heavy-chain kinase activity" NARROW [EC:2.7.11.7] +synonym: "myosin II heavy chain kinase activity" NARROW [EC:2.7.11.7] +synonym: "myosin II heavy-chain kinase activity" NARROW [EC:2.7.11.7] +synonym: "myosin-heavy-chain kinase activity" EXACT [EC:2.7.11.7] +synonym: "STK6" RELATED [EC:2.7.11.7] +xref: EC:2.7.11.7 +is_a: GO:0004683 ! calmodulin-dependent protein kinase activity + +[Term] +id: GO:0016906 +name: sterol 3-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol." [EC:2.4.1.173, RHEA:22724] +synonym: "sterol 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "sterol glucosyltransferase activity" EXACT [] +synonym: "sterol-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "sterol:UDPG glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose-sterol beta-glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "UDP-glucose-sterol glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "UDP-glucose:sterol glucosyltransferase activity" EXACT [] +synonym: "UDPG-SGTase activity" EXACT [EC:2.4.1.173] +synonym: "UDPG:sterol glucosyltransferase activity" EXACT [] +synonym: "UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "uridine diphosphoglucose-poriferasterol glucosyltransferase activity" EXACT [EC:2.4.1.173] +synonym: "uridine diphosphoglucose-sterol glucosyltransferase activity" EXACT [EC:2.4.1.173] +xref: EC:2.4.1.173 +xref: MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:22724 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0016907 +name: G protein-coupled acetylcholine receptor activity +namespace: molecular_function +alt_id: GO:0004981 +def: "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:fj, GOC:mah] +synonym: "acetylcholine receptor activity, G-protein coupled" EXACT [GOC:bf] +synonym: "G protein coupled acetylcholine receptor activity" EXACT [] +synonym: "G-protein coupled acetylcholine receptor activity" EXACT [] +synonym: "metabotropic acetylcholine receptor activity" EXACT [] +synonym: "muscarinic acetylcholine receptor activity" EXACT [] +is_a: GO:0008227 ! G protein-coupled amine receptor activity +is_a: GO:0015464 ! acetylcholine receptor activity +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +relationship: part_of GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway + +[Term] +id: GO:0016910 +name: obsolete SAP kinase 3 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a gene product. +synonym: "SAP kinase 3 activity" EXACT [] +synonym: "SAPK3" EXACT [] +is_obsolete: true +consider: GO:0004674 +consider: GO:0007254 + +[Term] +id: GO:0016911 +name: obsolete SAP kinase 4 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a gene product. +synonym: "SAP kinase 4 activity" EXACT [] +synonym: "SAPK4" EXACT [] +is_obsolete: true +consider: GO:0004674 +consider: GO:0007254 + +[Term] +id: GO:0016912 +name: obsolete SAP kinase 5 activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because there are no known gene products that would be described as 'SAP kinase 5', and the term name implies that it refers to a gene product. +synonym: "SAP kinase 5 activity" EXACT [] +synonym: "SAPK5" EXACT [] +is_obsolete: true +consider: GO:0004674 +consider: GO:0007254 + +[Term] +id: GO:0016913 +name: follicle-stimulating hormone activity +namespace: molecular_function +def: "The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis." [ISBN:0198547684] +synonym: "follicle stimulating hormone activity" EXACT [] +synonym: "follitropin activity" EXACT [ISBN:0198506732] +synonym: "FSH activity" EXACT [GOC:mah] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0016914 +name: follicle-stimulating hormone complex +namespace: cellular_component +def: "A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity." [ISBN:0198547684] +synonym: "follicle stimulating hormone complex" EXACT [] +synonym: "FSH complex" EXACT [] +is_a: GO:0061696 ! pituitary gonadotropin complex + +[Term] +id: GO:0016915 +name: obsolete activin +namespace: molecular_function +def: "OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone." [ISBN:0198506732, ISBN:0721662544] +comment: This term was made obsolete because it represents a gene product. +synonym: "activin" EXACT [] +is_obsolete: true +consider: GO:0005160 +consider: GO:0046881 + +[Term] +id: GO:0016916 +name: obsolete inhibin +namespace: molecular_function +def: "OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone." [ISBN:0198506732, ISBN:0721662544] +comment: This term was made obsolete because it represents a gene product. +synonym: "inhibin" EXACT [] +is_obsolete: true +consider: GO:0005160 +consider: GO:0046882 + +[Term] +id: GO:0016917 +name: GABA receptor activity +namespace: molecular_function +def: "Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms." [GOC:jl, GOC:signaling, PMID:10637650] +comment: See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'. +synonym: "4-aminobutanoate receptor activity" EXACT [] +synonym: "4-aminobutyrate receptor activity" EXACT [] +synonym: "GABA binding" EXACT [] +synonym: "gamma-aminobutyrate binding" EXACT [] +synonym: "gamma-aminobutyric acid binding" EXACT [] +synonym: "gamma-aminobutyric acid receptor activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0016918 +name: retinal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina." [ISBN:0198506732] +synonym: "blue-sensitive opsin" RELATED [] +synonym: "green-sensitive opsin" RELATED [] +synonym: "long-wave-sensitive opsin" RELATED [] +synonym: "opsin" RELATED [] +synonym: "red-sensitive opsin" RELATED [] +synonym: "retinaldehyde binding" EXACT [] +synonym: "short-wave-sensitive opsin" RELATED [] +synonym: "UV-sensitive opsin" RELATED [] +synonym: "violet-sensitive opsin" RELATED [] +synonym: "vitamin A binding" BROAD [] +is_a: GO:0005501 ! retinoid binding +is_a: GO:0019842 ! vitamin binding + +[Term] +id: GO:0016919 +name: obsolete nardilysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys." [EC:3.4.24.61] +comment: This term was made obsolete because it represents a gene product. +synonym: "N-arginine dibasic convertase activity" EXACT [EC:3.4.24.61] +synonym: "nardilysin activity" EXACT [] +synonym: "NRD convertase activity" EXACT [EC:3.4.24.61] +synonym: "NRD-convertase activity" EXACT [EC:3.4.24.61] +xref: EC:3.4.24.61 +xref: MetaCyc:3.4.24.61-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0016920 +name: pyroglutamyl-peptidase activity +namespace: molecular_function +def: "Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein." [EC:3.4.19.3, EC:3.4.19.6, GOC:mah] +xref: EC:3.4.19 +is_a: GO:0008242 ! omega peptidase activity + +[Term] +id: GO:0016921 +name: obsolete pyroglutamyl-peptidase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides." [EC:3.4.19.6] +comment: This term was made obsolete because it represents a gene product. +synonym: "PAP-II activity" EXACT [EC:3.4.19.6] +synonym: "pyroglutamate aminopeptidase II" RELATED [EC:3.4.19.6] +synonym: "pyroglutamyl aminopeptidase II activity" EXACT [EC:3.4.19.6] +synonym: "pyroglutamyl peptidase II" RELATED [EC:3.4.19.6] +synonym: "pyroglutamyl-peptidase II activity" EXACT [] +synonym: "thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] +synonym: "thyroliberinase activity" NARROW [EC:3.4.19.6] +synonym: "thyrotropin-releasing factor pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] +synonym: "thyrotropin-releasing hormone degrading ectoenzyme activity" NARROW [EC:3.4.19.6] +synonym: "thyrotropin-releasing hormone-degrading peptidase activity" EXACT [EC:3.4.19.6] +synonym: "thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] +synonym: "TRH-DE activity" NARROW [EC:3.4.19.6] +synonym: "TRH-degrading ectoenzyme activity" NARROW [EC:3.4.19.6] +synonym: "TRH-specific aminopeptidase activity" NARROW [EC:3.4.19.6] +xref: EC:3.4.19.6 +xref: MetaCyc:3.4.19.6-RXN +is_obsolete: true +consider: GO:0008237 +consider: GO:0016920 + +[Term] +id: GO:0016922 +name: nuclear receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein." [GOC:mah, PMID:7776974] +synonym: "ligand-dependent nuclear receptor binding" EXACT [] +synonym: "ligand-dependent nuclear receptor interactor activity" RELATED [] +is_a: GO:0035257 ! nuclear hormone receptor binding + +[Term] +id: GO:0016923 +name: obsolete ligand-dependent thyroid hormone receptor interactor activity +namespace: molecular_function +def: "OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor." [PMID:7776974] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "ligand-dependent thyroid hormone receptor interactor activity" EXACT [] +synonym: "TRIP4" RELATED [] +is_obsolete: true +consider: GO:0046966 + +[Term] +id: GO:0016925 +name: protein sumoylation +namespace: biological_process +alt_id: GO:0006485 +alt_id: GO:0016927 +def: "The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein." [GOC:jl, PMID:11265250] +synonym: "protein sumolation" EXACT [] +synonym: "small ubiquitin-related protein 1 conjugation" EXACT [] +synonym: "SUMO-protein conjugation" EXACT [] +synonym: "sumoylation" EXACT [] +xref: Wikipedia:SUMO_protein +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0032446 ! protein modification by small protein conjugation + +[Term] +id: GO:0016926 +name: protein desumoylation +namespace: biological_process +alt_id: GO:0016928 +def: "The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:jl, PMID:11265250] +synonym: "desumoylation" EXACT [] +synonym: "protein desumolation" EXACT [] +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0070646 ! protein modification by small protein removal + +[Term] +id: GO:0016929 +name: SUMO-specific protease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide or isopeptide bonds within SUMO, or between the SUMO and a larger protein to which it has been conjugated." [GOC:rn, PMID:10094048, PMID:11031248, PMID:11265250] +comment: This term should not be used for direct manual annotation because the supporting experiments should always distinguish whether the activity is part of maturation or SUMO removal. +subset: gocheck_do_not_manually_annotate +synonym: "SUSP" NARROW [] +synonym: "ULP" NARROW [] +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity + +[Term] +id: GO:0016933 +name: extracellularly glycine-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "extracellular-glycine-gated ion channel activity" EXACT [] +synonym: "glycine receptor" BROAD [] +is_a: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity + +[Term] +id: GO:0016934 +name: extracellularly glycine-gated chloride channel activity +namespace: molecular_function +alt_id: GO:0004891 +def: "Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "extracellular-glycine-gated chloride channel activity" EXACT [] +synonym: "glycine receptor" BROAD [] +synonym: "glycine-inhibited chloride channel activity" RELATED [] +xref: Reactome:R-HSA-975389 "GLRA:GLRB:Gly transports extracellular Cl- to cytosol" +is_a: GO:0005237 ! inhibitory extracellular ligand-gated ion channel activity +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0016933 ! extracellularly glycine-gated ion channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity + +[Term] +id: GO:0016935 +name: glycine-gated chloride channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts." [GOC:mah] +is_a: GO:0034707 ! chloride channel complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0016936 +name: galactoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any glycoside in which the sugar group is galactose." [GOC:jl, ISBN:0198506732] +subset: goslim_chembl +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0016937 +name: short-branched-chain-acyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue." [GOC:mah] +xref: EC:1.3.99 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0016938 +name: kinesin I complex +namespace: cellular_component +def: "A complex of two kinesin heavy chains and two kinesin light chains." [http://www.csfic.mi.cnr.it/centro/lines/8/ric.html] +is_a: GO:0005871 ! kinesin complex + +[Term] +id: GO:0016939 +name: kinesin II complex +namespace: cellular_component +def: "A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes." [http://www.csfic.mi.cnr.it/centro/lines/8/ric.html] +is_a: GO:0005871 ! kinesin complex + +[Term] +id: GO:0016941 +name: natriuretic peptide receptor activity +namespace: molecular_function +def: "Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity." [GOC:mah, GOC:signaling] +is_a: GO:0001653 ! peptide receptor activity + +[Term] +id: GO:0016942 +name: insulin-like growth factor binding protein complex +namespace: cellular_component +def: "A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development." [GOC:jl] +subset: goslim_pir +synonym: "IGF binding protein complex" EXACT [] +is_a: GO:0036454 ! growth factor complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0016943 +name: obsolete RNA polymerase I transcription elongation factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol I transcription elongation factor activity" EXACT [] +synonym: "RNA polymerase I transcription elongation factor activity" EXACT [] +is_obsolete: true +consider: GO:0006362 + +[Term] +id: GO:0016944 +name: obsolete RNA polymerase II transcription elongation factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol II transcription elongation factor activity" EXACT [] +synonym: "RNA polymerase II transcription elongation factor activity" EXACT [] +is_obsolete: true +consider: GO:0006368 + +[Term] +id: GO:0016945 +name: obsolete RNA polymerase III transcription elongation factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "Pol III transcription elongation factor activity" EXACT [] +synonym: "RNA polymerase III transcription elongation factor activity" EXACT [] +is_obsolete: true +consider: GO:0006385 + +[Term] +id: GO:0016946 +name: obsolete cathepsin F activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2." [EC:3.4.22.41] +comment: This term was made obsolete because it represents a gene product. +synonym: "cathepsin F activity" EXACT [] +xref: EC:3.4.22.41 +xref: MetaCyc:3.4.22.41-RXN +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0016962 +name: obsolete receptor-associated protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes a gene product and not a molecular function. +synonym: "receptor-associated protein activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 + +[Term] +id: GO:0016963 +name: obsolete alpha-2 macroglobulin receptor-associated protein activity +namespace: molecular_function +def: "OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains." [GOC:curators] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "alpha-2 macroglobulin receptor-associated protein activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 + +[Term] +id: GO:0016964 +name: alpha-2 macroglobulin receptor activity +namespace: molecular_function +def: "Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis." [GOC:bf, GOC:ma, PMID:6188403] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0016966 +name: nitric oxide reductase activity +namespace: molecular_function +alt_id: GO:0016967 +alt_id: GO:0016968 +def: "Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide." [EC:1.7.2.5] +synonym: "CYP55" NARROW [] +synonym: "cytochrome bc nitric oxide reductase activity" NARROW [] +synonym: "nitric-oxide reductase activity" EXACT [EC:1.7.2.5] +synonym: "nitrogen oxide reductase activity" EXACT [EC:1.7.2.5] +synonym: "nitrous-oxide:(acceptor) oxidoreductase (NO-forming)" EXACT [EC:1.7.2.5] +synonym: "nitrous-oxide:acceptor oxidoreductase (NO-forming)" EXACT [EC:1.7.2.5] +synonym: "P450 nitric oxide reductase activity" NARROW [] +synonym: "P450nor" NARROW [] +xref: EC:1.7.2.5 +xref: KEGG_REACTION:R00294 +xref: MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor + +[Term] +id: GO:0016969 +name: obsolete hemerythrin +namespace: molecular_function +def: "OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans." [GOC:ai, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "hemerythrin" EXACT [] +is_obsolete: true +replaced_by: GO:0005344 + +[Term] +id: GO:0016970 +name: obsolete hemocyanin +namespace: molecular_function +def: "OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods." [GOC:ai, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "hemocyanin" EXACT [] +is_obsolete: true +replaced_by: GO:0005344 + +[Term] +id: GO:0016971 +name: flavin-linked sulfhydryl oxidase activity +namespace: molecular_function +def: "Catalysis of the formation of disulfide bridges." [PMID:10899311] +is_a: GO:0016972 ! thiol oxidase activity + +[Term] +id: GO:0016972 +name: thiol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O." [EC:1.8.3.2] +synonym: "sulfhydryl oxidase activity" EXACT [EC:1.8.3.2] +synonym: "thiol:oxygen oxidoreductase activity" EXACT [EC:1.8.3.2] +xref: EC:1.8.3.2 +xref: MetaCyc:THIOL-OXIDASE-RXN +xref: RHEA:17357 +xref: UM-BBD_reactionID:r1293 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0016973 +name: poly(A)+ mRNA export from nucleus +namespace: biological_process +def: "The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm." [GOC:ai] +synonym: "poly(A) mRNA export from nucleus" EXACT [] +synonym: "poly(A)+ mRNA export from cell nucleus" EXACT [] +synonym: "poly(A)+ mRNA export out of nucleus" EXACT [] +synonym: "poly(A)+ mRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "poly(A)+ mRNA-nucleus export" EXACT [] +synonym: "polyadenylated mRNA export from nucleus" RELATED [] +is_a: GO:0006406 ! mRNA export from nucleus + +[Term] +id: GO:0016975 +name: obsolete alpha-2 macroglobulin +namespace: molecular_function +def: "OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates." [ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-2 macroglobulin" EXACT [] +is_obsolete: true +replaced_by: GO:0004866 + +[Term] +id: GO:0016977 +name: chitosanase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan." [EC:3.2.1.132] +synonym: "chitosan N-acetylglucosaminohydrolase activity" EXACT [EC:3.2.1.132] +xref: EC:3.2.1.132 +xref: MetaCyc:3.2.1.132-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0016979 +name: lipoate-protein ligase activity +namespace: molecular_function +alt_id: GO:0008916 +alt_id: GO:0016978 +alt_id: GO:0102315 +def: "Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP." [EC:6.3.1.20] +synonym: "lipoate-protein ligase A activity" NARROW [] +synonym: "lipoate-protein ligase activity (lipoylation of glycine cleavage complex)" NARROW [] +synonym: "lipoate-protein ligase B activity" NARROW [] +xref: MetaCyc:RXN-13039 +xref: MetaCyc:RXN-8654 +xref: MetaCyc:RXN-8655 +xref: MetaCyc:RXN0-1141 +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0016980 +name: creatinase activity +namespace: molecular_function +def: "Catalysis of the reaction: creatine + H(2)O = sarcosine + urea." [EC:3.5.3.3, RHEA:22456] +synonym: "creatine amidinohydrolase activity" EXACT [EC:3.5.3.3] +xref: EC:3.5.3.3 +xref: KEGG_REACTION:R01566 +xref: MetaCyc:CREATINASE-RXN +xref: RHEA:22456 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0016984 +name: ribulose-bisphosphate carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate." [EC:4.1.1.39] +synonym: "3-phospho-D-glycerate carboxy-lyase (dimerizing)" EXACT [EC:4.1.1.39] +synonym: "3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)" EXACT [EC:4.1.1.39] +synonym: "carboxydismutase activity" RELATED [EC:4.1.1.39] +synonym: "D-ribulose 1,5-diphosphate carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "D-ribulose-1,5-bisphosphate carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "diphosphoribulose carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose 1,5-bisphosphate carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose 1,5-bisphosphate carboxylase/oxygenase activity" EXACT [] +synonym: "ribulose 1,5-diphosphate carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose 1,5-diphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose bisphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose diphosphate carboxylase activity" EXACT [EC:4.1.1.39] +synonym: "ribulose diphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] +synonym: "RuBisCO activity" EXACT [EC:4.1.1.39] +synonym: "rubisco activity" EXACT [] +synonym: "RuBP carboxylase activity" EXACT [EC:4.1.1.39] +xref: EC:4.1.1.39 +xref: MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN +xref: RHEA:23124 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0016985 +name: mannan endo-1,4-beta-mannosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans." [EC:3.2.1.78] +synonym: "1,4-beta-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.78] +synonym: "beta-1,4-mannan 4-mannanohydrolase activity" EXACT [EC:3.2.1.78] +synonym: "beta-D-mannanase activity" EXACT [EC:3.2.1.78] +synonym: "beta-mannanase activity" BROAD [EC:3.2.1.78] +synonym: "beta-mannanase B" RELATED [EC:3.2.1.78] +synonym: "endo-1,4-beta-mannanase activity" EXACT [EC:3.2.1.78] +synonym: "endo-1,4-mannanase activity" BROAD [EC:3.2.1.78] +synonym: "endo-beta-1,4-mannase activity" EXACT [EC:3.2.1.78] +synonym: "endo-beta-mannanase activity" BROAD [EC:3.2.1.78] +xref: EC:3.2.1.78 +xref: MetaCyc:3.2.1.78-RXN +is_a: GO:0004567 ! beta-mannosidase activity + +[Term] +id: GO:0016986 +name: obsolete transcription initiation factor activity +namespace: molecular_function +def: "OBSOLETE. Plays a role in regulating transcription initiation." [GOC:curators] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "transcription initiation factor activity" EXACT [] +synonym: "transcriptional initiation factor activity" EXACT [] +is_obsolete: true +consider: GO:0140223 + +[Term] +id: GO:0016987 +name: sigma factor activity +namespace: molecular_function +alt_id: GO:0000996 +alt_id: GO:0001053 +def: "Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins." [GOC:txnOH-2018] +synonym: "bacterial sigma factor activity" NARROW [] +synonym: "core DNA-dependent RNA polymerase binding promoter specificity activity" EXACT [] +synonym: "DNA-dependent RNA polymerase promoter selection factor" EXACT [] +synonym: "plastid sigma factor activity" NARROW [] +synonym: "promoter selection factor activity" NARROW [] +synonym: "sigma factor activity" EXACT [] +synonym: "sigma transcription factor" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +intersection_of: GO:0140110 ! transcription regulator activity +intersection_of: has_part GO:0001046 ! core promoter sequence-specific DNA binding +intersection_of: has_part GO:0043175 ! RNA polymerase core enzyme binding +intersection_of: part_of GO:2000142 ! regulation of DNA-templated transcription, initiation +relationship: has_part GO:0001046 ! core promoter sequence-specific DNA binding +relationship: has_part GO:0043175 ! RNA polymerase core enzyme binding +relationship: part_of GO:2000142 ! regulation of DNA-templated transcription, initiation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14848 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15587 xsd:anyURI +created_by: krc +creation_date: 2010-08-11T04:12:24Z + +[Term] +id: GO:0016988 +name: obsolete transcription initiation factor antagonist activity +namespace: molecular_function +def: "OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity." [GOC:jl] +comment: This term was obsoleted because its definition was vague and apparently broader in scope than the name of the term suggested it was intended to be. +synonym: "transcription initiation factor antagonist activity" EXACT [] +synonym: "transcriptional initiation factor antagonist activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0016989 +name: sigma factor antagonist activity +namespace: molecular_function +def: "The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity." [GOC:jl, GOC:txnOH, Wikipedia:Anti-sigma_factors] +synonym: "anti-sigma factor activity" EXACT [] +is_a: GO:0003714 ! transcription corepressor activity + +[Term] +id: GO:0016990 +name: arginine deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3." [EC:3.5.3.6] +synonym: "arginine dihydrolase activity" EXACT [EC:3.5.3.6] +synonym: "citrulline iminase activity" EXACT [EC:3.5.3.6] +synonym: "L-arginine deiminase activity" EXACT [EC:3.5.3.6] +synonym: "L-arginine iminohydrolase activity" EXACT [EC:3.5.3.6] +xref: EC:3.5.3.6 +xref: MetaCyc:ARGININE-DEIMINASE-RXN +xref: RHEA:19597 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines +relationship: part_of GO:0018101 ! protein citrullination + +[Term] +id: GO:0016992 +name: lipoate synthase activity +namespace: molecular_function +alt_id: GO:0017140 +def: "Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl." [EC:2.8.1.8, PMID:18307109] +synonym: "LipA" RELATED [EC:2.8.1.8] +synonym: "lipoic acid synthase" EXACT [GOC:dph, GOC:tb] +synonym: "lipoyl synthase activity" EXACT [EC:2.8.1.8] +synonym: "LS" RELATED [EC:2.8.1.8] +synonym: "protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.8] +synonym: "protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.8] +xref: EC:2.8.1.8 +xref: MetaCyc:RXN0-949 +xref: Reactome:R-HSA-6793591 "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH" +is_a: GO:0016783 ! sulfurtransferase activity +relationship: part_of GO:0009107 ! lipoate biosynthetic process + +[Term] +id: GO:0016993 +name: precorrin-8X methylmutase activity +namespace: molecular_function +def: "Catalysis of the reaction: precorrin-8X = hydrogenobyrinate." [EC:5.4.99.61] +synonym: "HBA synthase activity" EXACT [EC:5.4.99.61] +synonym: "hydrogenobyrinic acid-binding protein activity" NARROW [EC:5.4.99.61] +synonym: "precorrin isomerase activity" EXACT [EC:5.4.99.61] +synonym: "precorrin-8X 11,12-methylmutase activity" EXACT [] +xref: EC:5.4.99.61 +xref: MetaCyc:5.4.1.2-RXN +xref: RHEA:22512 +is_a: GO:0016867 ! intramolecular transferase activity, transferring acyl groups + +[Term] +id: GO:0016994 +name: precorrin-6A reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+." [EC:1.3.1.54] +synonym: "precorrin-6B:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.54] +synonym: "precorrin-6X reductase activity" EXACT [] +synonym: "precorrin-6Y:NADP(+) oxidoreductase activity" EXACT [EC:1.3.1.54] +synonym: "precorrin-6Y:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.54] +xref: EC:1.3.1.54 +xref: MetaCyc:1.3.1.54-RXN +xref: RHEA:23408 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0016995 +name: cholesterol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2." [EC:1.1.3.6, RHEA:21328] +synonym: "3beta-hydroxy steroid oxidoreductase activity" EXACT [EC:1.1.3.6] +synonym: "3beta-hydroxysteroid:oxygen oxidoreductase activity" EXACT [EC:1.1.3.6] +synonym: "cholesterol- O2 oxidoreductase activity" EXACT [EC:1.1.3.6] +synonym: "cholesterol-O(2) oxidoreductase activity" EXACT [EC:1.1.3.6] +synonym: "cholesterol-O2 oxidoreductase activity" EXACT [EC:1.1.3.6] +synonym: "cholesterol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.6] +xref: EC:1.1.3.6 +xref: KEGG_REACTION:R01459 +xref: MetaCyc:CHOLESTEROL-OXIDASE-RXN +xref: RHEA:21328 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0016996 +name: endo-alpha-(2,8)-sialidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids." [EC:3.2.1.129] +synonym: "alpha-2,8-sialosylhydrolase activity" EXACT [EC:3.2.1.129] +synonym: "endo-N-acetylneuraminidase activity" EXACT [EC:3.2.1.129] +synonym: "endo-N-acylneuraminidase activity" EXACT [EC:3.2.1.129] +synonym: "endoneuraminidase activity" EXACT [EC:3.2.1.129] +synonym: "endosialidase activity" EXACT [EC:3.2.1.129] +synonym: "poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity" EXACT [EC:3.2.1.129] +synonym: "poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity" EXACT [EC:3.2.1.129] +synonym: "polysialoside (2->8)-alpha-sialosylhydrolase activity" EXACT [EC:3.2.1.129] +xref: EC:3.2.1.129 +xref: MetaCyc:3.2.1.129-RXN +is_a: GO:0016997 ! alpha-sialidase activity + +[Term] +id: GO:0016997 +name: alpha-sialidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids." [GOC:mah] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0016998 +name: cell wall macromolecule catabolic process +namespace: biological_process +alt_id: GO:0044039 +def: "The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall." [GOC:go_curators] +synonym: "cell wall breakdown" RELATED [GOC:mah] +synonym: "cell wall catabolism" RELATED [GOC:mah] +synonym: "cell wall degradation" RELATED [GOC:mah] +synonym: "cellular cell wall macromolecule breakdown" EXACT [GOC:mah] +synonym: "cellular cell wall macromolecule catabolic process" EXACT [] +synonym: "cellular cell wall macromolecule catabolism" EXACT [GOC:mah] +synonym: "cellular cell wall macromolecule degradation" EXACT [GOC:mah] +is_a: GO:0044036 ! cell wall macromolecule metabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process + +[Term] +id: GO:0016999 +name: antibiotic metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms." [GOC:cab2] +synonym: "antibiotic metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0017000 +name: antibiotic biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms." [GOC:go_curators] +subset: goslim_metagenomics +synonym: "antibiotic anabolism" EXACT [] +synonym: "antibiotic biosynthesis" EXACT [] +synonym: "antibiotic formation" EXACT [] +synonym: "antibiotic synthesis" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0017001 +name: antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms." [GOC:go_curators] +synonym: "antibiotic breakdown" EXACT [] +synonym: "antibiotic catabolism" EXACT [] +synonym: "antibiotic degradation" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0017002 +name: activin-activated receptor activity +namespace: molecular_function +def: "Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta." [GOC:mah, GOC:signaling, ISBN:0198506732] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "activin receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity +relationship: has_part GO:0048185 ! activin binding +relationship: part_of GO:0032924 ! activin receptor signaling pathway + +[Term] +id: GO:0017003 +name: protein-heme linkage +namespace: biological_process +def: "The covalent linkage of heme and a protein." [GOC:ma] +synonym: "protein-haem linkage" EXACT [] +is_a: GO:0017006 ! protein-tetrapyrrole linkage + +[Term] +id: GO:0017004 +name: cytochrome complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions." [GOC:jl, GOC:mah] +subset: goslim_metagenomics +synonym: "cytochrome biogenesis" BROAD [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0017005 +name: 3'-tyrosyl-DNA phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA." [PMID:10521354, PMID:16751265] +comment: See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'. +is_a: GO:0070259 ! tyrosyl-DNA phosphodiesterase activity + +[Term] +id: GO:0017006 +name: protein-tetrapyrrole linkage +namespace: biological_process +def: "The covalent linking of a tetrapyrrole to a protein." [GOC:ai] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0017007 +name: protein-bilin linkage +namespace: biological_process +def: "The covalent linkage of bilin and a protein." [GOC:ai] +is_a: GO:0017006 ! protein-tetrapyrrole linkage + +[Term] +id: GO:0017008 +name: protein-phycobiliviolin linkage +namespace: biological_process +def: "The linkage of the chromophore phycobiliviolin to phycoerythrocyanin." [RESID:AA0258] +xref: RESID:AA0258 +is_a: GO:0017007 ! protein-bilin linkage + +[Term] +id: GO:0017009 +name: protein-phycocyanobilin linkage +namespace: biological_process +def: "The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin." [RESID:AA0131] +xref: RESID:AA0131 +is_a: GO:0017007 ! protein-bilin linkage + +[Term] +id: GO:0017010 +name: protein-phycourobilin linkage +namespace: biological_process +def: "The linkage of the chromophore phycourobilin to phycoerythrins." [RESID:AA0260] +xref: RESID:AA0260 +is_a: GO:0017007 ! protein-bilin linkage + +[Term] +id: GO:0017011 +name: protein-phycoerythrobilin linkage +namespace: biological_process +def: "The linkage of the chromophore phycoerythrobilin to phycoerythrins." [RESID:AA0132, RESID:AA0259] +xref: RESID:AA0132 +is_a: GO:0017007 ! protein-bilin linkage + +[Term] +id: GO:0017012 +name: protein-phytochromobilin linkage +namespace: biological_process +def: "The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin." [RESID:AA0133] +xref: RESID:AA0133 +is_a: GO:0017007 ! protein-bilin linkage + +[Term] +id: GO:0017013 +name: protein flavinylation +namespace: biological_process +def: "The addition of a flavin group to a protein amino acid." [GOC:ai] +synonym: "protein amino acid flavinylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0017014 +name: protein nitrosylation +namespace: biological_process +def: "The covalent addition of a nitric oxide group to an amino acid within a protein." [GOC:ai, PMID:20972426] +synonym: "protein amino acid nitrosylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0017015 +name: regulation of transforming growth factor beta receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway." [GOC:mah] +synonym: "regulation of TGF-beta receptor signaling pathway" EXACT [] +synonym: "regulation of TGFbeta receptor signaling pathway" EXACT [] +synonym: "regulation of transforming growth factor beta receptor signalling pathway" EXACT [] +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:1903844 ! regulation of cellular response to transforming growth factor beta stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway +relationship: regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway + +[Term] +id: GO:0017016 +name: Ras GTPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases." [GOC:mah] +synonym: "Ras interactor activity" RELATED [] +is_a: GO:0031267 ! small GTPase binding + +[Term] +id: GO:0017017 +name: MAP kinase tyrosine/serine/threonine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate." [GOC:mah, PMID:12184814] +synonym: "dual-specificity MAP kinase phosphatase activity" EXACT [] +is_a: GO:0008138 ! protein tyrosine/serine/threonine phosphatase activity +is_a: GO:0033549 ! MAP kinase phosphatase activity + +[Term] +id: GO:0017018 +name: myosin phosphatase activity +namespace: molecular_function +alt_id: GO:0017019 +def: "Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate." [EC:3.1.3.16] +synonym: "myosin phosphatase myosin binding" RELATED [] +synonym: "myosin phosphatase, intrinsic catalyst activity" EXACT [] +xref: Reactome:R-HSA-390593 "ATP Hydrolysis By Myosin" +xref: Reactome:R-HSA-445699 "ATP Hydrolysis By Myosin" +is_a: GO:0004722 ! protein serine/threonine phosphatase activity + +[Term] +id: GO:0017020 +name: myosin phosphatase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme myosin phosphatase." [EC:3.1.3.16, GOC:ai] +synonym: "myosin phosphatase, intrinsic regulator activity" NARROW [] +is_a: GO:0019888 ! protein phosphatase regulator activity + +[Term] +id: GO:0017021 +name: obsolete myosin phosphatase myosin binding +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it describes the binding of myosin phosphatase to myosin, which is not a molecular function. +synonym: "myosin phosphatase myosin binding" EXACT [] +is_obsolete: true +consider: GO:0017018 +consider: GO:0017022 + +[Term] +id: GO:0017022 +name: myosin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +synonym: "myosin phosphatase myosin binding" NARROW [] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0017023 +name: myosin phosphatase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin." [EC:3.1.3.16] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex + +[Term] +id: GO:0017024 +name: myosin I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments." [GOC:bf, GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0017025 +name: TBP-class protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs)." [GOC:jl, GOC:txnOH, http://www.mblab.gla.ac.uk/, PMID:16858867] +synonym: "TATA-binding protein binding" NARROW [] +synonym: "TBP binding" NARROW [] +synonym: "TBP-related factor (TRF) protein binding" NARROW [] +is_a: GO:0140296 ! general transcription initiation factor binding + +[Term] +id: GO:0017026 +name: obsolete procollagen C-endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III." [EC:3.4.24.19] +comment: This term was made obsolete because it represents a gene product. +synonym: "BMP1" NARROW [] +synonym: "carboxyprocollagen peptidase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen C-endopeptidase activity" EXACT [] +synonym: "procollagen C-proteinase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen C-terminal peptidase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen C-terminal proteinase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen carboxy-terminal proteinase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen carboxypeptidase activity" EXACT [EC:3.4.24.19] +synonym: "procollagen peptidase activity" EXACT [EC:3.4.24.19] +xref: EC:3.4.24.19 +xref: MetaCyc:3.4.24.19-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0017027 +name: obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "transmembrane receptor protein serine/threonine kinase receptor-associated protein activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 + +[Term] +id: GO:0017028 +name: obsolete protein stabilization activity +namespace: molecular_function +def: "OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds." [GOC:jid] +comment: This term was made obsolete because it represents a biological process. +synonym: "protein stabilization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0050821 + +[Term] +id: GO:0017029 +name: obsolete lysosomal protein stabilization +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it contains both component and function information. +synonym: "lysosomal protein stabilization" EXACT [] +is_obsolete: true +consider: GO:0005764 +consider: GO:0050821 + +[Term] +id: GO:0017030 +name: obsolete beta-galactosidase stabilization activity +namespace: molecular_function +def: "OBSOLETE. Stabilization of the structure of beta-galactosidase." [GOC:ai] +comment: This term was made obsolete because it represents a biological process. +synonym: "beta-galactosidase stabilization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0050821 + +[Term] +id: GO:0017032 +name: amino acid:potassium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in)." [GOC:ai] +synonym: "potassium:amino acid symporter activity" EXACT [] +is_a: GO:0005416 ! amino acid:cation symporter activity +is_a: GO:0015079 ! potassium ion transmembrane transporter activity + +[Term] +id: GO:0017034 +name: Rap guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rap family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +is_a: GO:0005088 ! Ras guanyl-nucleotide exchange factor activity + +[Term] +id: GO:0017038 +name: protein import +namespace: biological_process +def: "The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event." [GOC:ai] +synonym: "protein uptake" EXACT [] +is_a: GO:0015031 ! protein transport + +[Term] +id: GO:0017039 +name: obsolete dipeptidyl-peptidase III activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides." [EC:3.4.14.4] +comment: This term was made obsolete because it represents a gene product. +synonym: "dipeptidyl aminopeptidase III activity" EXACT [EC:3.4.14.4] +synonym: "dipeptidyl arylamidase III activity" EXACT [EC:3.4.14.4] +synonym: "dipeptidyl-peptidase III activity" EXACT [] +synonym: "DPP III activity" EXACT [EC:3.4.14.4] +synonym: "enkephalinase B activity" NARROW [EC:3.4.14.4] +synonym: "red cell angiotensinase activity" NARROW [EC:3.4.14.4] +xref: EC:3.4.14.4 +xref: MetaCyc:3.4.14.4-RXN +is_obsolete: true +replaced_by: GO:0008239 + +[Term] +id: GO:0017040 +name: N-acylsphingosine amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine." [EC:3.5.1.23] +synonym: "acylsphingosine deacylase activity" EXACT [EC:3.5.1.23] +synonym: "glycosphingolipid ceramide deacylase" BROAD [EC:3.5.1.23] +synonym: "N-acylsphingosine amidohydrolase activity" EXACT [EC:3.5.1.23] +xref: EC:3.5.1.23 +xref: MetaCyc:CERAMIDASE-RXN +xref: Reactome:R-HSA-1606583 "Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane)" +xref: Reactome:R-HSA-1606602 "Acid ceramidase hydrolyses ceramide into sphingosine and free fatty acid (lysosome)" +xref: Reactome:R-HSA-428205 "ceramide + H2O => stearate + sphingosine [Golgi]" +xref: Reactome:R-HSA-428231 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]" +xref: RHEA:20856 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0017041 +name: galactosylgalactosylglucosylceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose." [EC:3.2.1.47] +synonym: "ceramide trihexosidase activity" EXACT [EC:3.2.1.47] +synonym: "ceramidetrihexosidase activity" EXACT [EC:3.2.1.47] +synonym: "ceramidetrihexoside alpha-galactosidase activity" EXACT [EC:3.2.1.47] +synonym: "D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity" EXACT [EC:3.2.1.47] +synonym: "trihexosyl ceramide galactosidase activity" EXACT [EC:3.2.1.47] +synonym: "trihexosylceramide alpha-galactosidase activity" EXACT [EC:3.2.1.47] +xref: EC:3.2.1.47 +xref: MetaCyc:3.2.1.47-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0017042 +name: glycosylceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine." [EC:3.2.1.62] +synonym: "cerebrosidase activity" EXACT [EC:3.2.1.62] +synonym: "glycosyl ceramide glycosylhydrolase activity" EXACT [EC:3.2.1.62] +synonym: "glycosyl-N-acylsphingosine glycohydrolase activity" EXACT [EC:3.2.1.62] +synonym: "lactase-phlorizin hydrolase" BROAD [EC:3.2.1.62] +synonym: "phloretin-glucosidase activity" EXACT [EC:3.2.1.62] +synonym: "phloridzin beta-glucosidase activity" EXACT [EC:3.2.1.62] +synonym: "phloridzin glucosidase activity" EXACT [EC:3.2.1.62] +synonym: "phlorizin hydrolase activity" EXACT [EC:3.2.1.62] +xref: EC:3.2.1.62 +xref: MetaCyc:GLYCOSYLCERAMIDASE-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0017043 +name: obsolete adrenocorticotropin +namespace: molecular_function +def: "OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "adrenocorticotropin" EXACT [] +synonym: "corticotropin" BROAD [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0046886 +consider: GO:0046887 + +[Term] +id: GO:0017044 +name: melanocyte-stimulating hormone activity +namespace: molecular_function +def: "The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates." [ISBN:0198506732] +synonym: "alpha-melanocyte stimulating hormone activity" NARROW [ISBN:0198506732] +synonym: "alpha-melanophore stimulating hormone activity" NARROW [ISBN:0198506732] +synonym: "melanocyte stimulating hormone activity" EXACT [] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0017045 +name: corticotropin-releasing hormone activity +namespace: molecular_function +def: "The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary." [ISBN:0198506732] +synonym: "adrenocorticotropin-releasing hormone" EXACT [] +xref: Wikipedia:Corticotropin-releasing_hormone +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0017046 +name: peptide hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any peptide with hormonal activity in animals." [GOC:jl, ISBN:0198506732] +synonym: "polypeptide hormone binding" EXACT [] +is_a: GO:0042277 ! peptide binding +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0017048 +name: Rho GTPase binding +namespace: molecular_function +alt_id: GO:0017031 +def: "Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton." [ISBN:0198547684, PMID:12581856] +synonym: "Rho interactor activity" RELATED [] +synonym: "Rhophilin" NARROW [] +is_a: GO:0017016 ! Ras GTPase binding + +[Term] +id: GO:0017049 +name: GTP-Rho binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the GTP-bound form of the Rho protein." [GOC:mah] +is_a: GO:0017048 ! Rho GTPase binding + +[Term] +id: GO:0017050 +name: D-erythro-sphingosine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP." [MetaCyc:RXN3DJ-11417] +synonym: "sphingosine kinase activity" EXACT [] +xref: MetaCyc:RXN3DJ-11417 +xref: Reactome:R-HSA-428273 "sphingosine +ATP => sphingosine 1-phosphate + ADP" +xref: Reactome:R-HSA-5218845 "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate" +xref: Reactome:R-HSA-9625814 "SPHK1 phosphorylates sphingosine in response to E2 stimulation" +is_a: GO:0016301 ! kinase activity + +[Term] +id: GO:0017051 +name: retinol dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol." [PMID:9857081] +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0017052 +name: obsolete insulin-like growth factor binding protein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "insulin-like growth factor binding protein" EXACT [] +is_obsolete: true +consider: GO:0016942 + +[Term] +id: GO:0017053 +name: transcription repressor complex +namespace: cellular_component +alt_id: GO:0090568 +alt_id: GO:0090569 +def: "A protein complex that possesses activity that prevents or downregulates transcription." [GOC:mah] +subset: goslim_pir +synonym: "cytoplasmic transcriptional repressor complex" RELATED [] +synonym: "nuclear transcriptional repressor complex" RELATED [] +synonym: "transcription factor inhibitor complex" EXACT [GOC:bhm] +synonym: "transcriptional repressor complex" EXACT [] +is_a: GO:0005667 ! transcription regulator complex +created_by: tb +creation_date: 2014-05-09T13:23:51Z + +[Term] +id: GO:0017054 +name: negative cofactor 2 complex +namespace: cellular_component +def: "A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini." [PMID:15574413] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex + +[Term] +id: GO:0017055 +name: negative regulation of RNA polymerase II transcription preinitiation complex assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly." [GOC:go_curators] +synonym: "down regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "down-regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "downregulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "inhibition of RNA polymerase II transcriptional preinitiation complex assembly" NARROW [] +synonym: "negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly" EXACT [] +synonym: "negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis" EXACT [] +synonym: "negative regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "negative regulation of RNA polymerase II transcriptional preinitiation complex formation" EXACT [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0045898 ! regulation of RNA polymerase II transcription preinitiation complex assembly +is_a: GO:0060633 ! negative regulation of transcription initiation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly +relationship: negatively_regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly + +[Term] +id: GO:0017056 +name: structural constituent of nuclear pore +namespace: molecular_function +alt_id: GO:0005487 +def: "The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules." [GOC:mah, PMID:25802992] +comment: Note that this term is meant to be used for nuclear pore proteins. For importins and exportins, consider 'nuclear import signal receptor activity' or 'nuclear export signal receptor activity', respectively. +synonym: "nuclear pore activity" RELATED [] +synonym: "nucleocytoplasmic transporter activity" EXACT [] +xref: Reactome:R-HSA-1176059 "Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus" +xref: Reactome:R-HSA-170796 "NPC transports GCK1:GKRP from cytosol to nucleoplasm" +xref: Reactome:R-HSA-192627 "Viral mRNA Export" +xref: Reactome:R-HSA-192925 "Export of Spliced Viral mRNA" +xref: Reactome:R-HSA-5252041 "NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm" +xref: Reactome:R-HSA-5578744 "Importin-8 imports AGO2:miRNA into the nucleus" +xref: Reactome:R-HSA-5661474 "Defective NPC does not transport GCK1:GKRP from cytosol to nucleoplasm" +xref: Reactome:R-HSA-6783483 "tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol" +xref: Reactome:R-HSA-75097 "Transport of the export-competent mRNP complex through the NPC" +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0005643 ! nuclear pore +relationship: occurs_in GO:0005643 ! nuclear pore +relationship: part_of GO:0006913 ! nucleocytoplasmic transport +created_by: tb +creation_date: 2015-06-29T08:59:16Z + +[Term] +id: GO:0017057 +name: 6-phosphogluconolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+)." [EC:3.1.1.31, RHEA:12556] +synonym: "6-PGL" RELATED [EC:3.1.1.31] +synonym: "6-phospho-D-glucono-1,5-lactone lactonohydrolase activity" EXACT [EC:3.1.1.31] +synonym: "phosphogluconolactonase activity" EXACT [EC:3.1.1.31] +xref: EC:3.1.1.31 +xref: KEGG_REACTION:R02035 +xref: MetaCyc:6PGLUCONOLACT-RXN +xref: Reactome:R-HSA-71296 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate" +xref: RHEA:12556 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0017058 +name: FH1 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain." [GOC:go_curators] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0017059 +name: serine C-palmitoyltransferase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine." [EC:2.3.1.50] +is_a: GO:0031211 ! endoplasmic reticulum palmitoyltransferase complex + +[Term] +id: GO:0017060 +name: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.65] +synonym: "(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "alpha(1,4)-L-fucosyltransferase activity" BROAD [] +synonym: "alpha-(1,3/1,4) fucosyltransferase III activity" BROAD [EC:2.4.1.65] +synonym: "alpha-(1,4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "alpha-(1->4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "alpha-4-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "beta-acetylglucosaminylsaccharide fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "blood group Lewis alpha-4-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "blood-group substance Le(a)-dependent fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "blood-group substance Lea-dependent fucosyltransferase" BROAD [EC:2.4.1.65] +synonym: "FucT-II activity" BROAD [EC:2.4.1.65] +synonym: "galactoside 3(4)-L-fucosyltransferase activity" BROAD [] +synonym: "GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] +synonym: "Lewis alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "Lewis alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "Lewis blood group alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] +synonym: "Lewis FT activity" BROAD [EC:2.4.1.65] +synonym: "Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity" BROAD [] +synonym: "Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity" NARROW [EC:2.4.1.65] +xref: EC:2.4.1.65 +xref: MetaCyc:2.4.1.65-RXN +xref: Reactome:R-HSA-5693925 "FUT3 transfers L-fucose to Gal1,3GlcNAc" +xref: Reactome:R-HSA-9603986 "FUT3 transfers Fuc to Type 1 chains to form LeA" +xref: RHEA:23628 +is_a: GO:0008417 ! fucosyltransferase activity + +[Term] +id: GO:0017061 +name: S-methyl-5-thioadenosine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate." [EC:2.4.2.28] +synonym: "5'-deoxy-5'-methylthioadenosine phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "5'-methylthioadenosine phosphorylase activity" EXACT [] +synonym: "5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity" EXACT [EC:2.4.2.28] +synonym: "MeSAdo phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "MeSAdo/Ado phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "methylthioadenosine nucleoside phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "methylthioadenosine phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "MTA phosphorylase activity" EXACT [EC:2.4.2.28] +synonym: "MTAPase activity" EXACT [EC:2.4.2.28] +synonym: "S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.28] +xref: EC:2.4.2.28 +xref: MetaCyc:5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN +xref: Reactome:R-HSA-1237160 "MTA is cleaved and phosphorylated" +is_a: GO:0004731 ! purine-nucleoside phosphorylase activity + +[Term] +id: GO:0017062 +name: respiratory chain complex III assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents." [GOC:jl, http://www.brainyencyclopedia.com/] +synonym: "coenzyme Q and cytochrome c reductase complex assembly" EXACT [] +synonym: "coenzyme Q and cytochrome c reductase complex biogenesis" EXACT [] +synonym: "complex III assembly" EXACT [] +synonym: "complex III biogenesis" EXACT [] +synonym: "cytochrome bc(1) complex assembly" EXACT [GOC:mcc] +synonym: "cytochrome bc(1) complex biogenesis" EXACT [] +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0017063 +name: obsolete phosphatidylserine-specific phospholipase A1 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.32] +comment: This term was made obsolete because the definition does not match the term name. +synonym: "phosphatidylserine-specific phospholipase A1 activity" EXACT [] +is_obsolete: true +consider: GO:0052739 +consider: GO:0052740 + +[Term] +id: GO:0017064 +name: fatty acid amide hydrolase activity +namespace: molecular_function +alt_id: GO:0017073 +def: "Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid." [PMID:15952893] +xref: Reactome:R-HSA-5693742 "FAAH hydrolyses AEA to AA and ETA" +xref: Reactome:R-HSA-5693751 "FAAH2 hydrolyses AEA to AA and ETA" +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0017065 +name: single-strand selective uracil DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA." [GOC:elh, PMID:9224623] +synonym: "single-strand selective monofunctional uracil-DNA glycosylase activity" EXACT [] +xref: Reactome:R-HSA-110221 "Cleavage of uracil by SMUG1 glycosylase" +is_a: GO:0004844 ! uracil DNA N-glycosylase activity + +[Term] +id: GO:0017067 +name: tyrosine-ester sulfotransferase activity +namespace: molecular_function +alt_id: GO:0008128 +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+)." [EC:2.8.2.9, RHEA:19977] +synonym: "3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity" EXACT [EC:2.8.2.9] +synonym: "aryl sulfotransferase IV" RELATED [EC:2.8.2.9] +synonym: "L-tyrosine methyl ester sulfotransferase activity" EXACT [EC:2.8.2.9] +synonym: "tyrosine-ester sulphotransferase activity" EXACT [] +xref: EC:2.8.2.9 +xref: KEGG_REACTION:R04213 +xref: MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN +xref: RHEA:19977 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0017069 +name: snRNA binding +namespace: molecular_function +alt_id: GO:0000945 +def: "Interacting selectively and non-covalently with a small nuclear RNA (snRNA)." [GOC:mah] +synonym: "base pairing with snRNA" NARROW [] +synonym: "small nuclear RNA binding" EXACT [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0017070 +name: U6 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA)." [GOC:mah] +comment: Note that this term may be useful for annotating small nuclear RNAs (snRNAs). +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0017071 +name: intracellular cyclic nucleotide activated cation channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts." [GOC:mah] +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0017072 +name: obsolete tubulin-specific chaperone activity +namespace: molecular_function +def: "OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function." [GOC:jl, PMID:11847227] +comment: This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. +synonym: "tubulin-specific chaperone activity" EXACT [] +is_obsolete: true +consider: GO:0007021 + +[Term] +id: GO:0017074 +name: obsolete procollagen N-endopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln." [EC:3.4.24.14] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminoprocollagen peptidase activity" EXACT [EC:3.4.24.14] +synonym: "aminoterminal procollagen peptidase activity" EXACT [EC:3.4.24.14] +synonym: "procollagen aminopeptidase activity" EXACT [EC:3.4.24.14] +synonym: "procollagen aminoterminal protease activity" EXACT [EC:3.4.24.14] +synonym: "procollagen N-endopeptidase activity" EXACT [] +synonym: "procollagen N-proteinase activity" EXACT [EC:3.4.24.14] +synonym: "procollagen N-terminal peptidase activity" EXACT [EC:3.4.24.14] +synonym: "procollagen N-terminal proteinase activity" EXACT [EC:3.4.24.14] +synonym: "type I/II procollagen N-proteinase activity" EXACT [EC:3.4.24.14] +synonym: "type III procollagen" RELATED [EC:3.4.24.14] +xref: EC:3.4.24.14 +xref: MetaCyc:3.4.24.14-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0017075 +name: syntaxin-1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the SNAP receptor syntaxin-1." [GOC:ai] +is_a: GO:0019905 ! syntaxin binding + +[Term] +id: GO:0017076 +name: purine nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] +is_a: GO:0000166 ! nucleotide binding + +[Term] +id: GO:0017077 +name: oxidative phosphorylation uncoupler activity +namespace: molecular_function +alt_id: GO:0015302 +def: "Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis." [PMID:15738989, PMID:16179945] +synonym: "mitochondrial uncoupling protein activity" NARROW [] +synonym: "uncoupling protein activity" NARROW [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0017078 +name: obsolete Hsc70 protein regulator activity +namespace: molecular_function +def: "OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70." [GOC:jl, PMID:11121403] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70 protein activity'. +synonym: "Hsc70 interacting protein" BROAD [] +synonym: "Hsc70 protein regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0031072 +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0017080 +name: sodium channel regulator activity +namespace: molecular_function +def: "Modulates the activity of a sodium channel." [GOC:mah] +is_a: GO:0016247 ! channel regulator activity +relationship: regulates GO:0005272 ! sodium channel activity + +[Term] +id: GO:0017081 +name: chloride channel regulator activity +namespace: molecular_function +def: "Modulates the activity of a chloride channel." [GOC:mah] +xref: Reactome:R-HSA-383190 "HCO3- transport through ion channel" +is_a: GO:0016247 ! channel regulator activity +relationship: regulates GO:0005254 ! chloride channel activity + +[Term] +id: GO:0017082 +name: obsolete mineralocorticoid receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II." [GOC:signaling, PMID:20932876] +synonym: "aldosterone receptor" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16732 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0017083 +name: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.152, RHEA:14257] +synonym: "galactoside 3-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "galactoside 3-L-fucosyltransferase activity" EXACT [] +synonym: "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "Lewis-negative alpha-3-fucosyltransferase activity" NARROW [EC:2.4.1.152] +synonym: "lewis-negative alpha-3-fucosyltransferase activity" EXACT [EC:2.4.1.152] +synonym: "plasma alpha-3-fucosyltransferase activity" NARROW [EC:2.4.1.152] +xref: EC:2.4.1.152 +xref: MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN +xref: RHEA:14257 +is_a: GO:0046920 ! alpha-(1->3)-fucosyltransferase activity + +[Term] +id: GO:0017084 +name: delta1-pyrroline-5-carboxylate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate." [MetaCyc:PROLINE-MULTI] +synonym: "D1-pyrroline-5-carboxylate synthetase activity" EXACT [] +xref: Reactome:R-HSA-508040 "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]" +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0017085 +name: response to insecticide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] +synonym: "insecticide resistance" RELATED [] +synonym: "insecticide susceptibility/resistance" RELATED [] +is_a: GO:0009636 ! response to toxic substance + +[Term] +id: GO:0017086 +name: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex +namespace: cellular_component +alt_id: GO:0031212 +def: "A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate." [EC:1.2.4.4] +synonym: "BCADH" EXACT [] +synonym: "branched-chain alpha-ketoacid dehydrogenase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0017087 +name: mitochondrial processing peptidase complex +namespace: cellular_component +def: "A protein complex that consists of a catalytic alpha subunit (alpha-MPP) and a regulatory beta subunit (beta-MPP), and catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion." [BRENDA:3.4.24.64, EC:3.4.24.64, GOC:mah] +comment: Note that monomeric mitochondrial processing peptidases have been observed. +is_a: GO:0098798 ! mitochondrial protein complex +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0017088 +name: obsolete X-Pro dipeptidyl-peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile." [EC:3.4.14.11] +comment: This term was made obsolete because it represents a gene product. +synonym: "PepX" RELATED [EC:3.4.14.11] +synonym: "X-Pro dipeptidyl-peptidase activity" EXACT [] +synonym: "X-prolyl dipeptidyl aminopeptidase activity" EXACT [EC:3.4.14.11] +synonym: "X-prolyl dipeptidyl peptidase activity" EXACT [EC:3.4.14.11] +synonym: "Xaa-Pro dipeptidyl-peptidase activity" EXACT [] +xref: EC:3.4.14.11 +xref: MetaCyc:3.4.14.11-RXN +is_obsolete: true +replaced_by: GO:0008239 + +[Term] +id: GO:0017089 +name: glycolipid transfer activity +namespace: molecular_function +def: "Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid." [PMID:30337668] +synonym: "glycolipid carrier activity" EXACT [] +synonym: "glycolipid transporter activity" BROAD [] +synonym: "intermembrane glycolipid transfer activity" NARROW [] +synonym: "intermembrane glycolipid transporter activity" NARROW [] +xref: Reactome:R-HSA-5340320 "GLTP transports GSL from plasma membrane to ER membrane" +is_a: GO:0120013 ! lipid transfer activity +relationship: has_part GO:0051861 ! glycolipid binding +relationship: part_of GO:0046836 ! glycolipid transport + +[Term] +id: GO:0017090 +name: meprin A complex +namespace: cellular_component +def: "A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues." [EC:3.4.24.18, GOC:mah, MEROPS_fam:M12] +synonym: "PABA peptide hydrolase complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016021 ! integral component of membrane + +[Term] +id: GO:0017091 +name: AU-rich element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases." [GOC:bf, GOC:mah, PMID:7892223, PMID:8578590] +synonym: "Adenylate/uridylate-rich element binding" EXACT [PMID:8578590] +synonym: "ARE binding" EXACT [] +synonym: "AU-specific RNA binding" EXACT [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0017092 +name: obsolete sterol regulatory element-binding protein site 2 protease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus." [GOC:bf, PMID:12923525] +comment: This term was made obsolete because it represents a gene product. +synonym: "SREBP site 2 protease activity" EXACT [] +synonym: "sterol regulatory element-binding protein site 2 protease activity" EXACT [] +is_obsolete: true +replaced_by: GO:0008237 + +[Term] +id: GO:0017093 +name: obsolete sterol regulatory element-binding protein protease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525] +comment: This term was made obsolete because it represents a gene product. +synonym: "SREBP protease activity" EXACT [] +synonym: "sterol regulatory element-binding protein protease activity" EXACT [] +is_obsolete: true +replaced_by: GO:0070011 + +[Term] +id: GO:0017094 +name: obsolete sterol regulatory element-binding protein site 1 protease activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves." [GOC:bf, PMID:12923525] +comment: This term was made obsolete because it represents a gene product. +synonym: "SREBP site 1 protease activity" EXACT [] +synonym: "sterol regulatory element-binding protein site 1 protease activity" EXACT [] +is_obsolete: true +replaced_by: GO:0008236 + +[Term] +id: GO:0017095 +name: heparan sulfate 6-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate." [PMID:8631808] +synonym: "heparan sulphate 6-O-sulphotransferase activity" EXACT [] +synonym: "heparin 6-O-sulfotransferase activity" RELATED [] +xref: EC:2.8.2 +xref: Reactome:R-HSA-2076419 "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin" +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0017096 +name: acetylserotonin O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0017097 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine." [EC:2.1.1.4] +synonym: "acetylserotonin methyltransferase activity" EXACT [EC:2.1.1.4] +synonym: "hydroxyindole methyltransferase activity" EXACT [EC:2.1.1.4] +synonym: "hydroxyindole O-methyltransferase activity" EXACT [EC:2.1.1.4] +synonym: "N-acetylserotonin O-methyltransferase activity" EXACT [EC:2.1.1.4] +synonym: "S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity" EXACT [EC:2.1.1.4] +xref: EC:2.1.1.4 +xref: MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN +xref: RHEA:15573 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0017098 +name: sulfonylurea receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel." [GOC:ceb, PMID:11938023] +synonym: "sulfonylurea receptor ligand" NARROW [] +synonym: "sulphonylurea receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0017099 +name: very-long-chain-acyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [GOC:mah] +synonym: "very long-chain-acyl-CoA dehydrogenase activity" EXACT [] +xref: EC:1.3.99 +xref: Reactome:R-HSA-548831 "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA" +is_a: GO:0004466 ! long-chain-acyl-CoA dehydrogenase activity + +[Term] +id: GO:0017101 +name: aminoacyl-tRNA synthetase multienzyme complex +namespace: cellular_component +def: "A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates." [GOC:jl, PMID:16169847] +synonym: "aminoacyl-tRNA synthetase complex" EXACT [] +synonym: "multisynthetase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0017102 +name: methionyl glutamyl tRNA synthetase complex +namespace: cellular_component +def: "A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers." [GOC:mcc, PMID:11069915] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0017103 +name: UTP:galactose-1-phosphate uridylyltransferase activity +namespace: molecular_function +alt_id: GO:0003982 +def: "Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose." [EC:2.7.7.10, RHEA:14209] +synonym: "alpha-D-galactose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] +synonym: "Gal-1-P uridylyltransferase activity" BROAD [EC:2.7.7.10] +synonym: "galactose 1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.10] +synonym: "galactose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] +synonym: "galactose-1-phosphate uridylyltransferase activity" BROAD [EC:2.7.7.10] +synonym: "UDPgalactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] +synonym: "uridine diphosphate galactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] +synonym: "uridine diphosphogalactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] +synonym: "UTP-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] +synonym: "UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] +synonym: "UTP:hexose-1-phosphate uridylyltransferase activity" BROAD [] +xref: EC:2.7.7.10 +xref: KEGG_REACTION:R00502 +xref: MetaCyc:UTPHEXPURIDYLYLTRANS-RXN +xref: RHEA:14209 +is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity + +[Term] +id: GO:0017105 +name: acyl-CoA delta11-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O." [EC:1.14.19.5] +synonym: "acyl-CoA D11-desaturase activity" EXACT [] +synonym: "acyl-CoA delta(11)-desaturase activity" EXACT [] +xref: EC:1.14.19.5 +is_a: GO:0016215 ! acyl-CoA desaturase activity + +[Term] +id: GO:0017106 +name: obsolete activin inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone." [ISBN:0198506732, ISBN:0721662544] +comment: This term was made obsolete because it refers to an obsolete molecular function term, 'activin'. +synonym: "activin inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0098772 + +[Term] +id: GO:0017107 +name: obsolete anion exchanger adaptor activity +namespace: molecular_function +def: "OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT_16mar07] +comment: The term was made obsolete because it referred to an interaction of an anion transporter with the AP1 adaptor by which it is probably transported, see: PMID:22744004; PMID:20833140; ie the adaptor does not specifically target an anion adaptor. +is_obsolete: true + +[Term] +id: GO:0017108 +name: 5'-flap endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis." [PMID:9778254] +synonym: "5' flap endonuclease activity" EXACT [] +xref: Reactome:R-HSA-110363 "FEN1 bound to PCNA and APEX1 cleaves flap ssDNA" +xref: Reactome:R-HSA-174446 "Removal of remaining Flap from the C-strand" +xref: Reactome:R-HSA-5651782 "FEN1 bound to POLB cleaves displaced DNA strand (flap)" +xref: Reactome:R-HSA-5687664 "FEN1 cleaves displaced ssDNA flaps during MMEJ" +xref: Reactome:R-HSA-69152 "Removal of remaining Flap" +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters +is_a: GO:0048256 ! flap endonuclease activity + +[Term] +id: GO:0017109 +name: glutamate-cysteine ligase complex +namespace: cellular_component +def: "An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine." [EC:6.3.2.2] +synonym: "gamma-glutamylcysteine synthetase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0017110 +name: nucleoside-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate." [EC:3.6.1.6] +synonym: "apyrase activity" BROAD [] +synonym: "IDPase" NARROW [EC:3.6.1.6] +synonym: "inosine 5'-diphosphatase" NARROW [EC:3.6.1.6] +synonym: "inosine diphosphatase" NARROW [EC:3.6.1.6] +synonym: "NDPase activity" EXACT [EC:3.6.1.6] +synonym: "nucleoside 5'-diphosphatase activity" EXACT [EC:3.6.1.6] +synonym: "nucleoside diphosphatase activity" EXACT [] +synonym: "nucleoside diphosphate phosphatase activity" EXACT [EC:3.6.1.6] +synonym: "nucleoside diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.6] +synonym: "nucleoside-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.6] +synonym: "type B nucleoside diphosphatase" NARROW [EC:3.6.1.6] +synonym: "type L nucleoside diphosphatase" NARROW [EC:3.6.1.6] +xref: EC:3.6.1.6 +xref: MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN +xref: Reactome:R-HSA-2395876 "NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP" +xref: Reactome:R-HSA-8850854 "NTPDase1 hydrolyzes nucleoside diphosphates" +xref: Reactome:R-HSA-8851129 "NTPDase3 hydrolyzes nucleoside diphosphates" +xref: Reactome:R-HSA-8851225 "NTPDase4 hydrolyzes nucleoside diphosphates" +xref: Reactome:R-HSA-8851356 "NTPDase5 hydrolyzes nucleoside diphosphates" +xref: Reactome:R-HSA-8851396 "NTPDase6 hydrolyzes nucleoside diphosphates" +xref: Reactome:R-HSA-8851550 "NTPDase8 hydrolyzes nucleoside diphosphates" +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0017111 +name: nucleoside-triphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate." [EC:3.6.1.15] +subset: goslim_chembl +subset: goslim_metagenomics +synonym: "apyrase activity" BROAD [] +synonym: "NTPase activity" EXACT [EC:3.6.1.15] +synonym: "nucleoside 5-triphosphatase activity" EXACT [EC:3.6.1.15] +synonym: "nucleoside triphosphatase activity" EXACT [] +synonym: "nucleoside triphosphate hydrolase activity" EXACT [EC:3.6.1.15] +synonym: "nucleoside triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] +synonym: "nucleoside-5-triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] +synonym: "unspecific diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] +xref: EC:3.6.1.15 +xref: MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN +xref: Reactome:R-HSA-8850846 "NTPDase1 hydrolyzes nucleoside triphosphates" +xref: Reactome:R-HSA-8851089 "NTPDase2 hydrolyzes nucleoside triphosphates" +xref: Reactome:R-HSA-8851110 "NTPDase3 hydrolyzes nucleoside triphosphates" +xref: Reactome:R-HSA-8851234 "NTPDase4 hydrolyzes nucleoside triphosphates" +xref: Reactome:R-HSA-8851494 "NTPDase7 hydrolyzes nucleoside triphosphates" +xref: Reactome:R-HSA-8851538 "NTPDase8 hydrolyzes nucleoside triphosphates" +xref: RHEA:23680 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0017112 +name: Rab guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +xref: Reactome:R-HSA-5617816 "RAB3IP stimulates nucleotide exchange on RAB8A" +xref: Reactome:R-HSA-5623521 "RAB3IP stimulates nucleotide exchange on RAB8A" +xref: Reactome:R-HSA-8875318 "RAB3 GEFs exchange GTP for GDP on RAB3A" +xref: Reactome:R-HSA-8875320 "RAB5 GEFs exchange GTP for GDP on RAB5" +xref: Reactome:R-HSA-8876188 "DENND4s exchange GTP for GDP on RAB10" +xref: Reactome:R-HSA-8876190 "RAB8 GEFs exchange GTP for GDP on RAB8" +xref: Reactome:R-HSA-8876191 "RAB9 GEFs exchange GTP for GDP on RAB9" +xref: Reactome:R-HSA-8876193 "RIC1-RGP1 exchanges GTP for GDP on RAB6" +xref: Reactome:R-HSA-8876454 "DENND3 exchanges GTP for GDP on RAB12" +xref: Reactome:R-HSA-8876615 "RAB13 GEFs exchange GTP for GDP on RAB13" +xref: Reactome:R-HSA-8876616 "DENND6A,B exchange GTP for GDP on RAB14" +xref: Reactome:R-HSA-8876837 "RAB21 GEFs exchange GTP for GDP on RAB21" +xref: Reactome:R-HSA-8877308 "MADD exchanges GTP for GDP on RAB27" +xref: Reactome:R-HSA-8877311 "RAB31 GEFs exchange GTP for GDP on RAB31" +xref: Reactome:R-HSA-8877451 "MON1:CCZ1 exchanges GTP for GDP on RAB7" +xref: Reactome:R-HSA-8877475 "TRAPPC complexes exchange GTP for GDP on RAB1" +xref: Reactome:R-HSA-8877612 "DENND1s exchange GTP for GDP on RAB35" +xref: Reactome:R-HSA-8877760 "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38" +xref: Reactome:R-HSA-8877813 "DENND5A,B exchange GTP for GDP on RAB39" +xref: Reactome:R-HSA-8877998 "RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18" +is_a: GO:0005088 ! Ras guanyl-nucleotide exchange factor activity +is_a: GO:0017137 ! Rab GTPase binding + +[Term] +id: GO:0017113 +name: dihydropyrimidine dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+." [EC:1.3.1.2] +synonym: "4,5-dihydrothymine: oxidoreductase activity" EXACT [EC:1.3.1.2] +synonym: "5,6-dihydrouracil:NADP+ 5-oxidoreductase activity" EXACT [EC:1.3.1.2] +synonym: "dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.2] +synonym: "DHPDH" RELATED [EC:1.3.1.2] +synonym: "DHU dehydrogenase activity" EXACT [EC:1.3.1.2] +synonym: "dihydropyrimidine dehydrogenase activity" EXACT [] +synonym: "dihydrothymine dehydrogenase activity" RELATED [EC:1.3.1.2] +synonym: "dihydrouracil dehydrogenase (NADP)" EXACT [EC:1.3.1.2] +synonym: "dihydrouracil dehydrogenase (NADP+) activity" EXACT [EC:1.3.1.2] +synonym: "DPD" RELATED [EC:1.3.1.2] +synonym: "hydropyrimidine dehydrogenase activity" EXACT [EC:1.3.1.2] +xref: EC:1.3.1.2 +xref: MetaCyc:1.3.1.2-RXN +xref: Reactome:R-HSA-73585 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+" +xref: Reactome:R-HSA-73616 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+" +xref: RHEA:18093 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0017114 +name: obsolete wide-spectrum protease inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it represents a regulator of non-existent molecular function. +synonym: "wide-spectrum protease inhibitor activity" EXACT [] +synonym: "wide-spectrum proteinase inhibitor" EXACT [] +is_obsolete: true +replaced_by: GO:0030414 + +[Term] +id: GO:0017116 +name: single-stranded DNA helicase activity +namespace: molecular_function +alt_id: GO:0043142 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix." [GOC:jl] +synonym: "single-stranded DNA-dependent ATP-dependent DNA helicase activity" EXACT [] +synonym: "single-stranded DNA-dependent ATPase activity" EXACT [] +synonym: "ssDNA-dependent ATP-dependent DNA helicase activity" EXACT [GOC:mah] +synonym: "ssDNA-dependent ATPase activity" EXACT [] +is_a: GO:0003678 ! DNA helicase activity + +[Term] +id: GO:0017117 +name: single-stranded DNA-dependent ATP-dependent DNA helicase complex +namespace: cellular_component +def: "A protein complex that possesses single-stranded DNA-dependent DNA helicase activity." [GOC:mah] +synonym: "ssDNA-dependent ATP-dependent DNA helicase complex" EXACT [GOC:mah] +is_a: GO:0033202 ! DNA helicase complex + +[Term] +id: GO:0017118 +name: lipoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme." [PMID:10103005] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0017119 +name: Golgi transport complex +namespace: cellular_component +def: "A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p). In mammals the subunits are named COG1-8." [GOC:krc, PMID:11980916, PMID:20972446, PMID:9792665] +synonym: "COG complex" EXACT [] +synonym: "conserved oligomeric Golgi complex" EXACT [] +synonym: "Sec34/35 complex" NARROW [] +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0017120 +name: obsolete polyphosphatidylinositol phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization." [PMID:10224048] +comment: This term was made obsolete because it represents a gene product. +synonym: "polyphosphatidylinositol phosphatase activity" EXACT [] +synonym: "polyphosphoinositide phosphatase activity" EXACT [] +is_obsolete: true +consider: GO:0004438 +consider: GO:0034593 +consider: GO:0043812 + +[Term] +id: GO:0017121 +name: plasma membrane phospholipid scrambling +namespace: biological_process +def: "The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE)." [GOC:cjm, PMID:20043909, PMID:20302864] +comment: Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'. +synonym: "phospholipid scrambling" RELATED [] +synonym: "PL scrambling" EXACT [] +is_a: GO:0007009 ! plasma membrane organization +is_a: GO:0045332 ! phospholipid translocation + +[Term] +id: GO:0017122 +name: protein N-acetylglucosaminyltransferase complex +namespace: cellular_component +def: "A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits." [PMID:15247246] +synonym: "O-GlcNAc transferase complex" EXACT [GOC:mah] +synonym: "UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase" EXACT [GOC:mah] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16994 xsd:anyURI + +[Term] +id: GO:0017124 +name: SH3 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins." [GOC:go_curators, Pfam:PF00018] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0017125 +name: deoxycytidyl transferase activity +namespace: molecular_function +alt_id: GO:0019986 +def: "Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA." [PMID:10535901] +synonym: "deoxycytidyl transferase activity, template-dependent" NARROW [] +xref: Reactome:R-HSA-110308 "REV1 inserts dCMP opposite to AP sites in DNA" +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0017126 +name: nucleologenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732] +synonym: "nucleolus assembly" NARROW [GOC:mah] +synonym: "nucleolus biogenesis" EXACT [] +is_a: GO:0007000 ! nucleolus organization +is_a: GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0017128 +name: phospholipid scramblase activity +namespace: molecular_function +def: "Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism." [GOC:cjm, PMID:20043909, PMID:20302864] +comment: Nomenclature note. Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Some authors however use the name floppase to denote any enzyme catalyzing transbilayer lipid motion, in some cases even in the absence of ATP requirements (PMID 20043909). +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0140303 ! intramembrane lipid transporter activity +relationship: part_of GO:0017121 ! plasma membrane phospholipid scrambling + +[Term] +id: GO:0017129 +name: triglyceride binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any triester of glycerol." [GOC:jl, ISBN:0198506732] +synonym: "triacylglycerol binding" EXACT [GOC:mah] +is_a: GO:0008289 ! lipid binding + +[Term] +id: GO:0017130 +name: poly(C) RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence of cytosine residues in an RNA molecule." [GOC:mah] +synonym: "poly(C) binding" BROAD [GOC:mah] +synonym: "poly(rC) binding" EXACT [GOC:mah] +is_a: GO:0008187 ! poly-pyrimidine tract binding + +[Term] +id: GO:0017131 +name: uridine-rich cytoplasmic polyadenylylation element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation." [GOC:krc, PMID:7954828] +synonym: "U-rich CPE binding" EXACT [PMID:7954828] +synonym: "uridine-rich cytoplasmic polyadenylation element binding" EXACT [] +is_a: GO:0008187 ! poly-pyrimidine tract binding + +[Term] +id: GO:0017132 +name: cAMP-dependent guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase, when activated by cAMP binding." [GOC:mah, PMID:9856955] +is_a: GO:0005085 ! guanyl-nucleotide exchange factor activity +relationship: has_part GO:0030552 ! cAMP binding + +[Term] +id: GO:0017133 +name: mitochondrial electron transfer flavoprotein complex +namespace: cellular_component +def: "A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system." [GOC:mtg_sensu, ISBN:0198506732] +is_a: GO:0045251 ! electron transfer flavoprotein complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0045251 ! electron transfer flavoprotein complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0017134 +name: fibroblast growth factor binding +namespace: molecular_function +alt_id: GO:0048602 +alt_id: GO:0048603 +alt_id: GO:0048604 +alt_id: GO:0048605 +alt_id: GO:0048606 +alt_id: GO:0048607 +def: "Interacting selectively and non-covalently with a fibroblast growth factor." [PMID:9806903] +synonym: "FGF 1 binding" NARROW [] +synonym: "FGF 2 binding" NARROW [] +synonym: "FGF 3 binding" NARROW [] +synonym: "FGF 4 binding" NARROW [] +synonym: "FGF 5 binding" NARROW [] +synonym: "FGF 6 binding" NARROW [] +synonym: "FGF binding" EXACT [] +synonym: "fibroblast growth factor 1 binding" NARROW [] +synonym: "fibroblast growth factor 2 binding" NARROW [] +synonym: "fibroblast growth factor 3 binding" NARROW [] +synonym: "fibroblast growth factor 4 binding" NARROW [] +synonym: "fibroblast growth factor 5 binding" NARROW [] +synonym: "fibroblast growth factor 6 binding" NARROW [] +is_a: GO:0019838 ! growth factor binding + +[Term] +id: GO:0017135 +name: obsolete membrane-associated protein with guanylate kinase activity interacting +namespace: molecular_function +def: "OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity." [PMID:10207005] +comment: This term was made obsolete because it does not represent a molecular function and the term name appears to make no sense. +synonym: "membrane-associated protein with guanylate kinase activity interacting" EXACT [] +is_obsolete: true +consider: GO:0019899 + +[Term] +id: GO:0017136 +name: NAD-dependent histone deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone." [EC:3.5.1.17, RHEA:24548] +synonym: "SIR2" RELATED [] +is_a: GO:0004407 ! histone deacetylase activity +is_a: GO:0034979 ! NAD-dependent protein deacetylase activity + +[Term] +id: GO:0017137 +name: Rab GTPase binding +namespace: molecular_function +alt_id: GO:0005084 +def: "Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases." [GOC:mah] +synonym: "Rab escort protein activity" NARROW [] +synonym: "Rab interactor activity" RELATED [] +synonym: "REP" NARROW [] +is_a: GO:0017016 ! Ras GTPase binding + +[Term] +id: GO:0017139 +name: obsolete arsenate sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "arsenate sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046685 + +[Term] +id: GO:0017141 +name: obsolete antibiotic susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "antibiotic susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046677 + +[Term] +id: GO:0017142 +name: obsolete toxin susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "toxin susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0009636 + +[Term] +id: GO:0017143 +name: insecticide metabolic process +namespace: biological_process +alt_id: GO:0017138 +def: "The chemical reactions and pathways involving insecticides, chemicals used to kill insects." [GOC:ai] +synonym: "insecticide metabolism" EXACT [] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0009404 ! toxin metabolic process +relationship: part_of GO:0017085 ! response to insecticide + +[Term] +id: GO:0017144 +name: drug metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice." [GOC:cab2] +subset: goslim_chembl +subset: goslim_pir +synonym: "drug metabolism" EXACT [] +xref: Wikipedia:Drug_metabolism +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0017145 +name: stem cell division +namespace: biological_process +def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] +synonym: "stem cell renewal" EXACT [] +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0017146 +name: NMDA selective glutamate receptor complex +namespace: cellular_component +def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html] +synonym: "N-methyl-D-aspartate selective glutamate receptor complex" EXACT [] +synonym: "NMDA-selective glutamate receptor" EXACT [] +is_a: GO:0008328 ! ionotropic glutamate receptor complex +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0017147 +name: Wnt-protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling." [GOC:jl] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0017148 +name: negative regulation of translation +namespace: biological_process +alt_id: GO:0016478 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] +synonym: "down regulation of protein biosynthetic process" EXACT [] +synonym: "down-regulation of protein biosynthetic process" EXACT [] +synonym: "downregulation of protein biosynthetic process" EXACT [] +synonym: "inhibition of protein biosynthetic process" NARROW [] +synonym: "negative regulation of protein anabolism" EXACT [] +synonym: "negative regulation of protein biosynthesis" EXACT [] +synonym: "negative regulation of protein biosynthetic process" EXACT [] +synonym: "negative regulation of protein formation" EXACT [] +synonym: "negative regulation of protein synthesis" EXACT [] +synonym: "protein biosynthesis inhibitor activity" RELATED [] +synonym: "protein biosynthetic process inhibitor activity" RELATED [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0032269 ! negative regulation of cellular protein metabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006412 ! translation +relationship: negatively_regulates GO:0006412 ! translation + +[Term] +id: GO:0017149 +name: obsolete protein biosynthetic process inhibitor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents involvement in a biological process. +synonym: "protein anabolism inhibitor activity" EXACT [] +synonym: "protein biosynthetic process inhibitor activity" EXACT [] +synonym: "protein formation inhibitor activity" EXACT [] +synonym: "protein synthesis inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0017148 + +[Term] +id: GO:0017150 +name: tRNA dihydrouridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor." [PMID:11983710] +xref: MetaCyc:RXN0-1281 +xref: Reactome:R-HSA-6782296 "DUS2:EPRS reduces uridine to dihydrouridine in tRNAs" +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0002943 ! tRNA dihydrouridine synthesis + +[Term] +id: GO:0017151 +name: DEAD/H-box RNA helicase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase." [GOC:jl] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0017153 +name: sodium:dicarboxylate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in)." [GOC:ai] +synonym: "sodium:dicarboxylate cotransporter activity" BROAD [] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0005343 ! organic acid:sodium symporter activity + +[Term] +id: GO:0017154 +name: semaphorin receptor activity +namespace: molecular_function +def: "Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:mah, GOC:signaling, PMID:15239958] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0071526 ! semaphorin-plexin signaling pathway + +[Term] +id: GO:0017155 +name: obsolete sodium:hydrogen antiporter regulator activity +namespace: molecular_function +alt_id: GO:0030040 +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because it represents a biological process. +synonym: "sodium:hydrogen antiporter regulator activity" EXACT [] +synonym: "sodium:proton antiporter regulator" EXACT [] +is_obsolete: true + +[Term] +id: GO:0017156 +name: calcium-ion regulated exocytosis +namespace: biological_process +def: "The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels." [GOC:go_curators] +comment: Note that the calcium regulated exocytosis pathway can be leaky: some level of exocytosis via this pathway occurs spontaneously. This phenomenon underlies spontaneous neurotransmitter release from presynapses. This phenomenon is distinct from the unregulated, calcium independent exocytosis pathway. +synonym: "calcium ion-dependent exocytosis" EXACT [] +is_a: GO:0045055 ! regulated exocytosis + +[Term] +id: GO:0017157 +name: regulation of exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006887 ! exocytosis +relationship: regulates GO:0006887 ! exocytosis + +[Term] +id: GO:0017158 +name: regulation of calcium ion-dependent exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis." [GOC:go_curators] +is_a: GO:1903305 ! regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017156 ! calcium-ion regulated exocytosis +relationship: regulates GO:0017156 ! calcium-ion regulated exocytosis + +[Term] +id: GO:0017159 +name: pantetheine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine." [EC:3.5.1.92, RHEA:13445] +synonym: "(R)-pantetheine amidohydrolase activity" EXACT [EC:3.5.1.92] +synonym: "pantetheinase activity" EXACT [EC:3.5.1.92] +synonym: "vanin" RELATED [EC:3.5.1.92] +synonym: "vanin-1" RELATED [EC:3.5.1.92] +xref: EC:3.5.1.92 +xref: KEGG_REACTION:R02973 +xref: MetaCyc:3.5.1.92-RXN +xref: Reactome:R-HSA-8938300 "Vanin hydrolyses pantetheine to PanK, 2AET" +xref: RHEA:13445 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0017160 +name: Ral GTPase binding +namespace: molecular_function +alt_id: GO:0034989 +def: "Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases." [GOC:mah] +synonym: "GTP-Ral binding" NARROW [] +synonym: "Ral interactor activity" RELATED [] +is_a: GO:0017016 ! Ras GTPase binding + +[Term] +id: GO:0017161 +name: inositol-1,3,4-trisphosphate 4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855180 "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol" +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity + +[Term] +id: GO:0017162 +name: aryl hydrocarbon receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an aryl hydrocarbon receptor." [GOC:ai] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding + +[Term] +id: GO:0017163 +name: obsolete basal transcription repressor activity +namespace: molecular_function +def: "OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter." [GOC:dph, GOC:tb, http://tfib.med.harvard.edu/transcription/basaltx.html] +comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "basal transcription repressor activity" EXACT [] +is_obsolete: true +consider: GO:0001217 +consider: GO:0001227 +consider: GO:0045892 + +[Term] +id: GO:0017164 +name: obsolete nicotinic acetylcholine receptor-associated protein activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product and not a molecular function. +synonym: "nicotinic acetylcholine receptor-associated protein activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0005515 + +[Term] +id: GO:0017165 +name: obsolete dipeptidase E activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides." [EC:3.4.13.21] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-aspartyl dipeptidase activity" EXACT [] +synonym: "aspartyl dipeptidase activity" EXACT [EC:3.4.13.21] +synonym: "dipeptidase E activity" EXACT [] +synonym: "PepE gene product (Salmonella typhimurium) activity" NARROW [EC:3.4.13.21] +synonym: "peptidase E activity" BROAD [EC:3.4.13.21] +xref: EC:3.4.13.21 +xref: MetaCyc:3.4.13.21-RXN +is_obsolete: true +replaced_by: GO:0016805 + +[Term] +id: GO:0017166 +name: vinculin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane." [ISBN:0721662544] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0017168 +name: 5-oxoprolinase (ATP-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate." [EC:3.5.2.9, RHEA:10348] +synonym: "5-OPase activity" EXACT [EC:3.5.2.9] +synonym: "5-oxo-L-prolinase activity" EXACT [EC:3.5.2.9] +synonym: "5-oxo-L-proline amidohydrolase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] +synonym: "5-oxoprolinase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] +synonym: "5-oxoprolinase activity" EXACT [EC:3.5.2.9] +synonym: "L-pyroglutamate hydrolase activity" EXACT [EC:3.5.2.9] +synonym: "oxoprolinase activity" EXACT [EC:3.5.2.9] +synonym: "pyroglutamase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] +synonym: "pyroglutamase (ATP-hydrolyzing) activity" EXACT [EC:3.5.2.9] +synonym: "pyroglutamase activity" EXACT [EC:3.5.2.9] +synonym: "pyroglutamate hydrolase activity" EXACT [EC:3.5.2.9] +synonym: "pyroglutamic hydrolase activity" EXACT [EC:3.5.2.9] +xref: EC:3.5.2.9 +xref: KEGG_REACTION:R00251 +xref: MetaCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN +xref: Reactome:R-HSA-1247935 "OPLAH hydrolyses OPRO to L-Glu" +xref: Reactome:R-HSA-5603208 "Defective OPLAH does not hydrolyse OPRO" +xref: RHEA:10348 +xref: Wikipedia:5-oxoprolinase_(ATP-hydrolysing) +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0017169 +name: CDP-alcohol phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol." [GOC:ai] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0017170 +name: obsolete KU70 binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with Ku70, a protein involved in non-homologous DNA end joining." [GOC:mah, PMID:14739985] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "KU70 binding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0017171 +name: serine hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [Wikipedia:Serine_hydrolase] +is_a: GO:0016825 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds + +[Term] +id: GO:0017172 +name: cysteine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+)." [EC:1.13.11.20, RHEA:20441] +xref: EC:1.13.11.20 +xref: KEGG_REACTION:R00893 +xref: MetaCyc:CYSTEINE-DIOXYGENASE-RXN +xref: Reactome:R-HSA-1614645 "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine" +xref: RHEA:20441 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0017174 +name: glycine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine." [EC:2.1.1.20] +synonym: "glycine methyltransferase activity" EXACT [EC:2.1.1.20] +synonym: "GNMT" RELATED [EC:2.1.1.20] +synonym: "S-adenosyl-L-methionine:glycine methyltransferase activity" EXACT [EC:2.1.1.20] +synonym: "S-adenosyl-L-methionine:glycine N-methyltransferase activity" EXACT [EC:2.1.1.20] +xref: EC:2.1.1.156 +xref: EC:2.1.1.162 +xref: EC:2.1.1.20 +xref: KEGG_REACTION:R00367 +xref: MetaCyc:2.1.1.162-RXN +xref: MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-6798317 "GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC" +xref: RHEA:19937 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0017175 +name: obsolete IMP-GMP specific 5'-nucleotidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile." [EC:3.1.3.5, GOC:krc] +comment: This term was made obsolete because it represents a gene product with two different activities. +synonym: "IMP-GMP specific 5'-nucleotidase activity" EXACT [] +is_obsolete: true +consider: GO:0050484 + +[Term] +id: GO:0017176 +name: phosphatidylinositol N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol." [EC:2.4.1.198] +synonym: "UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity" EXACT [EC:2.4.1.198] +synonym: "UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] +synonym: "uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] +synonym: "uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] +xref: EC:2.4.1.198 +xref: MetaCyc:2.4.1.198-RXN +xref: RHEA:14789 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0017177 +name: glucosidase II complex +namespace: cellular_component +def: "A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins." [PMID:10464333, PMID:8910335] +comment: Note that alpha-glucosidase I functions as a monomer, and therefore does not have a corresponding cellular component term. +synonym: "alpha-glucosidase II complex" RELATED [GOC:19605557, GOC:vw] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0017178 +name: diphthine-ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate." [EC:6.3.1.14, RHEA:19753] +synonym: "diphthamide synthase activity" EXACT [EC:6.3.1.14] +synonym: "diphthamide synthetase activity" EXACT [EC:6.3.1.14] +synonym: "diphthine:ammonia ligase (ADP-forming)" EXACT [EC:6.3.1.14] +xref: EC:6.3.1.14 +xref: KEGG_REACTION:R03613 +xref: MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN +xref: Reactome:R-HSA-5358475 "DPH6 ligates ammonium to diphthine-EEF2" +xref: RHEA:19753 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0017179 +name: peptidyl-diphthine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue." [GOC:go_curators] +synonym: "peptidyl-diphthine metabolism" EXACT [] +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0017180 +name: peptidyl-diphthine biosynthetic process from peptidyl-histidine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine." [GOC:go_curators] +synonym: "peptidyl-diphthine anabolism from peptidyl-histidine" EXACT [] +synonym: "peptidyl-diphthine formation from peptidyl-histidine" EXACT [] +synonym: "peptidyl-diphthine synthesis from peptidyl-histidine" EXACT [] +is_a: GO:0017179 ! peptidyl-diphthine metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0017181 +name: peptidyl-diphthine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue." [GOC:go_curators] +synonym: "peptidyl-diphthine breakdown" EXACT [] +synonym: "peptidyl-diphthine catabolism" EXACT [] +synonym: "peptidyl-diphthine degradation" EXACT [] +is_a: GO:0017179 ! peptidyl-diphthine metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0017182 +name: peptidyl-diphthamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue." [GOC:go_curators] +synonym: "peptidyl-diphthamide metabolism" EXACT [] +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0017183 +name: peptidyl-diphthamide biosynthetic process from peptidyl-histidine +namespace: biological_process +def: "The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria." [GOC:pde, PMID:20559380, RESID:AA0040] +synonym: "peptidyl-diphthamide anabolism from peptidyl-histidine" EXACT [] +synonym: "peptidyl-diphthamide formation from peptidyl-histidine" EXACT [] +synonym: "peptidyl-diphthamide synthesis from peptidyl-histidine" EXACT [] +xref: RESID:AA0040 +is_a: GO:0017182 ! peptidyl-diphthamide metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1900247 ! regulation of cytoplasmic translational elongation + +[Term] +id: GO:0017184 +name: peptidyl-diphthamide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue." [GOC:go_curators] +synonym: "peptidyl-diphthamide breakdown" EXACT [] +synonym: "peptidyl-diphthamide catabolism" EXACT [] +synonym: "peptidyl-diphthamide degradation" EXACT [] +is_a: GO:0017182 ! peptidyl-diphthamide metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0017185 +name: peptidyl-lysine hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine." [GOC:ai] +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0017186 +name: peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase." [RESID:AA0031] +comment: See also the molecular function term 'glutaminyl-peptide cyclotransferase activity ; GO:0016603'. +synonym: "2-pyrrolidone-5-carboxylic acid biosynthesis" EXACT [] +synonym: "2-pyrrolidone-5-carboxylic acid biosynthetic process" EXACT [] +synonym: "peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase" EXACT [] +synonym: "peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase" EXACT [] +synonym: "peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase" EXACT [] +xref: RESID:AA0031 +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0017187 +name: peptidyl-glutamic acid carboxylation +namespace: biological_process +def: "The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase." [RESID:AA0032] +comment: See also the molecular function term 'gamma-glutamyl carboxylase activity ; GO:0008488'. +xref: RESID:AA0032 +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018214 ! protein carboxylation + +[Term] +id: GO:0017188 +name: aspartate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+)." [EC:2.3.1.17, RHEA:14165] +synonym: "acetyl-CoA:L-aspartate N-acetyltransferase activity" EXACT [EC:2.3.1.17] +synonym: "aspartate acetyltransferase activity" EXACT [EC:2.3.1.17] +synonym: "L-aspartate N-acetyltransferase activity" EXACT [EC:2.3.1.17] +xref: EC:2.3.1.17 +xref: KEGG_REACTION:R00487 +xref: MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN +xref: Reactome:R-HSA-8954468 "NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA" +xref: RHEA:14165 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0017189 +name: N-terminal peptidyl-alanine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase." [RESID:AA0041] +comment: See also the molecular function terms 'peptide alpha-N-acetyltransferase activity ; GO:0004596' and 'ribosomal-protein-alanine N-acetyltransferase activity ; GO:0008999'. +xref: RESID:AA0041 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0017190 +name: N-terminal peptidyl-aspartic acid acetylation +namespace: biological_process +def: "The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase." [RESID:AA0042] +comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'. +xref: RESID:AA0042 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0017192 +name: N-terminal peptidyl-glutamine acetylation +namespace: biological_process +def: "The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable." [RESID:AA0045] +xref: RESID:AA0045 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0017193 +name: N-terminal peptidyl-glycine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine." [RESID:AA0046] +xref: RESID:AA0046 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0017194 +name: N-terminal peptidyl-isoleucine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed." [RESID:AA0047] +xref: RESID:AA0047 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018203 ! peptidyl-isoleucine modification + +[Term] +id: GO:0017195 +name: N-terminal peptidyl-lysine N2-acetylation +namespace: biological_process +def: "The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed." [RESID:AA0048] +xref: RESID:AA0048 +is_a: GO:0018076 ! N-terminal peptidyl-lysine acetylation + +[Term] +id: GO:0017196 +name: N-terminal peptidyl-methionine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine." [RESID:AA0049] +xref: RESID:AA0049 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018206 ! peptidyl-methionine modification + +[Term] +id: GO:0017197 +name: N-terminal peptidyl-proline acetylation +namespace: biological_process +def: "The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline." [RESID:AA0050] +xref: RESID:AA0050 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0017198 +name: N-terminal peptidyl-serine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine." [RESID:AA0051] +xref: RESID:AA0051 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0030920 ! peptidyl-serine acetylation + +[Term] +id: GO:0017199 +name: N-terminal peptidyl-threonine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase." [RESID:AA0052] +comment: See also the molecular function term 'peptide alpha-N-acetyltransferase activity ; GO:0004596'. +xref: RESID:AA0052 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018000 +name: N-terminal peptidyl-tyrosine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine." [RESID:AA0053] +xref: RESID:AA0053 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018001 +name: N-terminal peptidyl-valine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine." [RESID:AA0054] +xref: RESID:AA0054 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018213 ! peptidyl-valine modification + +[Term] +id: GO:0018002 +name: N-terminal peptidyl-glutamic acid acetylation +namespace: biological_process +def: "The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid." [RESID:AA0044] +comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'. +xref: RESID:AA0044 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018003 +name: peptidyl-lysine N6-acetylation +namespace: biological_process +def: "The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine." [RESID:AA0055] +comment: See also the molecular function term 'tubulin N-acetyltransferase activity ; GO:0019799'. +xref: RESID:AA0055 +is_a: GO:0018393 ! internal peptidyl-lysine acetylation + +[Term] +id: GO:0018004 +name: N-terminal protein formylation +namespace: biological_process +def: "The formylation of the N-terminal amino acid of proteins." [GOC:ai] +is_a: GO:0018256 ! protein formylation +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0018005 +name: N-terminal peptidyl-glycine N-formylation +namespace: biological_process +def: "The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine." [RESID:AA0057] +xref: RESID:AA0057 +is_a: GO:0018004 ! N-terminal protein formylation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018006 +name: N-terminal protein amino acid glucuronylation +namespace: biological_process +def: "The glucuronylation of the N-terminal amino acid of proteins." [GOC:ai] +is_a: GO:0018321 ! protein glucuronylation +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0018007 +name: N-terminal peptidyl-glycine N-glucuronylation +namespace: biological_process +def: "The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine." [RESID:AA0058] +xref: RESID:AA0058 +is_a: GO:0018006 ! N-terminal protein amino acid glucuronylation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018008 +name: N-terminal peptidyl-glycine N-myristoylation +namespace: biological_process +def: "The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine." [RESID:AA0059] +synonym: "N-terminal peptidyl-glycine N-myristylation" EXACT [] +xref: RESID:AA0059 +is_a: GO:0006499 ! N-terminal protein myristoylation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018009 +name: N-terminal peptidyl-L-cysteine N-palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine." [RESID:AA0060] +xref: RESID:AA0060 +is_a: GO:0006500 ! N-terminal protein palmitoylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018010 +name: glycoprotein N-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein." [EC:2.3.1.96] +synonym: "mucus glycoprotein fatty acyltransferase" NARROW [EC:2.3.1.96] +synonym: "palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity" EXACT [EC:2.3.1.96] +xref: MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN +is_a: GO:0019105 ! N-palmitoyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0018011 +name: N-terminal peptidyl-alanine methylation +namespace: biological_process +def: "The methylation of the N-terminal alanine of proteins." [RESID:AA0061, RESID:AA0062] +xref: RESID:AA0061 +xref: RESID:AA0062 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0018012 +name: N-terminal peptidyl-alanine trimethylation +namespace: biological_process +def: "The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine." [RESID:AA0062] +xref: RESID:AA0062 +is_a: GO:0018011 ! N-terminal peptidyl-alanine methylation + +[Term] +id: GO:0018013 +name: N-terminal peptidyl-glycine methylation +namespace: biological_process +def: "The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine." [RESID:AA0063] +xref: RESID:AA0063 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018014 +name: N-terminal peptidyl-methionine methylation +namespace: biological_process +def: "The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine." [RESID:AA0064] +xref: RESID:AA0064 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018206 ! peptidyl-methionine modification + +[Term] +id: GO:0018015 +name: N-terminal peptidyl-phenylalanine methylation +namespace: biological_process +def: "The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine." [RESID:AA0065] +xref: RESID:AA0065 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0018016 +name: N-terminal peptidyl-proline dimethylation +namespace: biological_process +def: "The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline." [RESID:AA0066] +xref: RESID:AA0066 +is_a: GO:0035568 ! N-terminal peptidyl-proline methylation + +[Term] +id: GO:0018019 +name: N-terminal peptidyl-glutamine methylation +namespace: biological_process +def: "The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative." [RESID:AA0071] +xref: RESID:AA0071 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0018020 +name: peptidyl-glutamic acid methylation +namespace: biological_process +def: "The addition of a methyl group to a glutamic acid residue in a protein." [GOC:mah] +is_a: GO:0006479 ! protein methylation + +[Term] +id: GO:0018021 +name: peptidyl-histidine methylation +namespace: biological_process +def: "The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)." [RESID:AA0073, RESID:AA0317] +xref: RESID:AA0073 +xref: RESID:AA0317 +is_a: GO:0006479 ! protein methylation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018022 +name: peptidyl-lysine methylation +namespace: biological_process +def: "The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative." [GOC:ai] +is_a: GO:0006479 ! protein methylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018023 +name: peptidyl-lysine trimethylation +namespace: biological_process +def: "The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine." [RESID:AA0074] +xref: RESID:AA0074 +is_a: GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0018024 +name: histone-lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives." [EC:2.1.1.43, RESID:AA0074, RESID:AA0075, RESID:AA0076] +synonym: "histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity" EXACT [EC:2.1.1.43] +synonym: "histone-lysine N-methylase activity" EXACT [GOC:mah] +synonym: "protein (lysine) methyltransferase activity" EXACT [EC:2.1.1.43] +synonym: "protein methylase 3 activity" NARROW [EC:2.1.1.43] +synonym: "protein methylase III activity" NARROW [EC:2.1.1.43] +synonym: "protein methyltransferase II activity" NARROW [EC:2.1.1.43] +synonym: "S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.43] +synonym: "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.43] +xref: EC:2.1.1.43 +xref: MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-3788745 "EHMT1:EHMT2 methylates IL8 promoter" +xref: Reactome:R-HSA-3788748 "EHMT1:EHMT2 methylates IL6 promoter" +xref: Reactome:R-HSA-4827382 "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)" +xref: Reactome:R-HSA-4827383 "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)" +xref: Reactome:R-HSA-5159245 "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)" +xref: Reactome:R-HSA-5244692 "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)" +xref: Reactome:R-HSA-5423038 "SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)" +xref: Reactome:R-HSA-5634729 "EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9)" +xref: Reactome:R-HSA-5634750 "EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9)" +xref: Reactome:R-HSA-5634802 "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)" +xref: Reactome:R-HSA-5637686 "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)" +xref: Reactome:R-HSA-5638141 "SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36)" +xref: Reactome:R-HSA-5638157 "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)" +xref: Reactome:R-HSA-5638332 "PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)" +xref: Reactome:R-HSA-5638333 "WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)" +xref: Reactome:R-HSA-5649764 "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)" +xref: Reactome:R-HSA-5649799 "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)" +xref: Reactome:R-HSA-5649800 "WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27)" +xref: Reactome:R-HSA-5649801 "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)" +xref: Reactome:R-HSA-5649802 "WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27)" +xref: Reactome:R-HSA-5651654 "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)" +xref: Reactome:R-HSA-5651657 "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)" +xref: RESID:AA0074 +xref: RESID:AA0075 +xref: RESID:AA0076 +is_a: GO:0016279 ! protein-lysine N-methyltransferase activity +is_a: GO:0042054 ! histone methyltransferase activity +relationship: part_of GO:0034968 ! histone lysine methylation + +[Term] +id: GO:0018025 +name: calmodulin-lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine." [EC:2.1.1.60] +synonym: "S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.60] +synonym: "S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.60] +synonym: "S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity" EXACT [EC:2.1.1.60] +xref: EC:2.1.1.60 +xref: MetaCyc:2.1.1.60-RXN +xref: Reactome:R-HSA-6786205 "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1" +is_a: GO:0016279 ! protein-lysine N-methyltransferase activity + +[Term] +id: GO:0018026 +name: peptidyl-lysine monomethylation +namespace: biological_process +def: "The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine." [RESID:AA0076] +xref: RESID:AA0076 +is_a: GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0018027 +name: peptidyl-lysine dimethylation +namespace: biological_process +def: "The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine." [RESID:AA0075] +xref: RESID:AA0075 +is_a: GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0018028 +name: peptidyl-lysine myristoylation +namespace: biological_process +def: "The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine." [RESID:AA0078] +synonym: "peptidyl-lysine myristylation" EXACT [] +xref: RESID:AA0078 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018377 ! protein myristoylation + +[Term] +id: GO:0018029 +name: peptidyl-lysine palmitoylation +namespace: biological_process +def: "The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine." [RESID:AA0077] +xref: RESID:AA0077 +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018030 +name: peptidyl-lysine N6-myristoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule." [GOC:mah] +is_a: GO:0019107 ! myristoyltransferase activity + +[Term] +id: GO:0018031 +name: peptidyl-lysine N6-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule." [GOC:mah] +xref: EC:2.3.1 +is_a: GO:0019105 ! N-palmitoyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0018032 +name: protein amidation +namespace: biological_process +def: "Addition of an amide group from a glycine to a protein amino acid." [UniProtKB-KW:KW-0027] +synonym: "protein amino acid amidation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018033 +name: protein C-terminal amidation +namespace: biological_process +def: "The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein." [GOC:ai] +is_a: GO:0018032 ! protein amidation +is_a: GO:0018410 ! C-terminal protein amino acid modification + +[Term] +id: GO:0018034 +name: C-terminal peptidyl-alanine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein." [RESID:AA0081] +xref: RESID:AA0081 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0018035 +name: C-terminal peptidyl-arginine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein." [RESID:AA0082] +xref: RESID:AA0082 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0018036 +name: C-terminal peptidyl-asparagine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein." [RESID:AA0083] +xref: RESID:AA0083 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018037 +name: C-terminal peptidyl-aspartic acid amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein." [RESID:AA0084] +xref: RESID:AA0084 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0018038 +name: C-terminal peptidyl-cysteine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein." [RESID:AA0085] +xref: RESID:AA0085 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018039 +name: C-terminal peptidyl-glutamine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein." [RESID:AA0086] +xref: RESID:AA0086 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0018040 +name: C-terminal peptidyl-glutamic acid amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein." [RESID:AA0087] +xref: RESID:AA0087 +is_a: GO:0018033 ! protein C-terminal amidation + +[Term] +id: GO:0018041 +name: C-terminal peptidyl-glycine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein." [RESID:AA0088] +xref: RESID:AA0088 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018042 +name: C-terminal peptidyl-histidine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein." [RESID:AA0089] +xref: RESID:AA0089 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018043 +name: C-terminal peptidyl-isoleucine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein." [RESID:AA0090] +xref: RESID:AA0090 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018203 ! peptidyl-isoleucine modification + +[Term] +id: GO:0018044 +name: C-terminal peptidyl-leucine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein." [RESID:AA0091] +xref: RESID:AA0091 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018204 ! peptidyl-leucine modification + +[Term] +id: GO:0018045 +name: C-terminal peptidyl-lysine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein." [RESID:AA0092] +xref: RESID:AA0092 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018046 +name: C-terminal peptidyl-methionine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein." [RESID:AA0093] +xref: RESID:AA0093 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018206 ! peptidyl-methionine modification + +[Term] +id: GO:0018047 +name: C-terminal peptidyl-phenylalanine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein." [RESID:AA0094] +xref: RESID:AA0094 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0018048 +name: C-terminal peptidyl-proline amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein." [RESID:AA0095] +xref: RESID:AA0095 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0018049 +name: C-terminal peptidyl-serine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein." [RESID:AA0096] +xref: RESID:AA0096 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018050 +name: C-terminal peptidyl-threonine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein." [RESID:AA0097] +xref: RESID:AA0097 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018051 +name: C-terminal peptidyl-tryptophan amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein." [RESID:AA0098] +xref: RESID:AA0098 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0018052 +name: C-terminal peptidyl-tyrosine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein." [RESID:AA0099] +xref: RESID:AA0099 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018053 +name: C-terminal peptidyl-valine amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein." [RESID:AA0100] +xref: RESID:AA0100 +is_a: GO:0018033 ! protein C-terminal amidation +is_a: GO:0018213 ! peptidyl-valine modification + +[Term] +id: GO:0018054 +name: peptidyl-lysine biotinylation +namespace: biological_process +def: "The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine." [RESID:AA0117] +xref: RESID:AA0117 +is_a: GO:0009305 ! protein biotinylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018057 +name: peptidyl-lysine oxidation +namespace: biological_process +def: "The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens." [ISBN:0198547684, RESID:AA0121] +xref: RESID:AA0121 +is_a: GO:0018158 ! protein oxidation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018058 +name: N-terminal protein amino acid deamination, from amino carbon +namespace: biological_process +def: "The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol." [RESID:AA0127, RESID:AA0128, RESID:AA0129] +xref: RESID:AA0127 +xref: RESID:AA0128 +xref: RESID:AA0129 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018277 ! protein deamination +is_a: GO:0031363 ! N-terminal protein amino acid deamination + +[Term] +id: GO:0018059 +name: N-terminal peptidyl-serine deamination +namespace: biological_process +def: "The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue." [RESID:AA0127] +is_a: GO:0018058 ! N-terminal protein amino acid deamination, from amino carbon + +[Term] +id: GO:0018060 +name: N-terminal peptidyl-cysteine deamination +namespace: biological_process +def: "The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue." [RESID:AA0127] +is_a: GO:0018058 ! N-terminal protein amino acid deamination, from amino carbon + +[Term] +id: GO:0018061 +name: peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine +namespace: biological_process +def: "The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid." [RESID:AA0128] +synonym: "peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine" EXACT [] +synonym: "peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine" EXACT [] +synonym: "peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine" EXACT [] +xref: RESID:AA0128 +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0018062 +name: peptidyl-tryptophan succinylation +namespace: biological_process +def: "The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan." [RESID:AA0130] +xref: RESID:AA0130 +is_a: GO:0018211 ! peptidyl-tryptophan modification +is_a: GO:0018335 ! protein succinylation +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0018063 +name: cytochrome c-heme linkage +namespace: biological_process +def: "The linkage of cytochromes and other heme proteins to heme." [RESID:AA0134, RESID:AA0135] +synonym: "cytochrome c-haem linkage" EXACT [] +xref: RESID:AA0134 +xref: RESID:AA0135 +is_a: GO:0017003 ! protein-heme linkage +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0018064 +name: protein-histidine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine." [EC:2.1.1.85] +synonym: "actin-specific histidine methyltransferase activity" EXACT [EC:2.1.1.85] +synonym: "peptidyl-histidine N-methyltransferase activity" EXACT [] +synonym: "protein (histidine) methyltransferase activity" EXACT [EC:2.1.1.85] +synonym: "protein methylase IV activity" NARROW [EC:2.1.1.85] +synonym: "S-adenosyl methionine:protein-histidine N-methyltransferase activity" EXACT [EC:2.1.1.85] +synonym: "S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity" EXACT [EC:2.1.1.85] +xref: EC:2.1.1.85 +xref: MetaCyc:2.1.1.85-RXN +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0018065 +name: protein-cofactor linkage +namespace: biological_process +def: "The covalent attachment of a cofactor to a protein." [GOC:ai] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018067 +name: peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine +namespace: biological_process +def: "The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA)." [RESID:AA0146] +synonym: "peptidyl-L-3',4'-dihydroxyphenylalanine anabolism from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-3',4'-dihydroxyphenylalanine formation from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-3',4'-dihydroxyphenylalanine synthesis from peptidyl-tyrosine" EXACT [] +xref: RESID:AA0146 +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018336 ! peptidyl-tyrosine hydroxylation + +[Term] +id: GO:0018068 +name: peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine +namespace: biological_process +def: "The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases." [RESID:AA0147] +synonym: "peptidyl-L-2',4',5'-topaquinone anabolism from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-2',4',5'-topaquinone formation from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-2',4',5'-topaquinone synthesis from peptidyl-tyrosine" EXACT [] +xref: RESID:AA0147 +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018069 +name: peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone +namespace: biological_process +def: "The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase." [RESID:AA0149] +xref: RESID:AA0149 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0018070 +name: peptidyl-serine phosphopantetheinylation +namespace: biological_process +def: "The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine." [RESID:AA0150] +xref: RESID:AA0150 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018215 ! protein phosphopantetheinylation + +[Term] +id: GO:0018071 +name: NAD(P)-cysteine ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine." [EC:2.4.2.-] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0018072 +name: peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid +namespace: biological_process +def: "The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit." [PMID:2569467, RESID:AA0170] +synonym: "peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine anabolism from peptidyl-glutamic acid" EXACT [] +synonym: "peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine formation from peptidyl-glutamic acid" EXACT [] +synonym: "peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine synthesis from peptidyl-glutamic acid" EXACT [] +xref: RESID:AA0170 +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018073 +name: protein bromination +namespace: biological_process +def: "The addition of one or more bromine atoms to an amino acid residue in a protein." [GOC:mah] +synonym: "protein amino acid bromination" EXACT [GOC:bf] +is_a: GO:0018079 ! protein halogenation + +[Term] +id: GO:0018074 +name: peptidyl-histidine bromination +namespace: biological_process +def: "The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown." [RESID:AA0173] +xref: RESID:AA0173 +is_a: GO:0018073 ! protein bromination +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018075 +name: peptidyl-phenylalanine bromination +namespace: biological_process +def: "The bromination of phenylalanine." [RESID:AA0174, RESID:AA0175, RESID:AA0176] +xref: RESID:AA0174 +xref: RESID:AA0175 +xref: RESID:AA0176 +is_a: GO:0018073 ! protein bromination +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0018076 +name: N-terminal peptidyl-lysine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal lysine of proteins." [GOC:ai] +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018394 ! peptidyl-lysine acetylation + +[Term] +id: GO:0018077 +name: protein iodination +namespace: biological_process +def: "The addition of one or more iodine atoms to an amino acid residue in a protein." [GOC:mah] +synonym: "protein amino acid iodination" EXACT [GOC:bf] +is_a: GO:0018079 ! protein halogenation + +[Term] +id: GO:0018078 +name: peptidyl-thyronine iodination +namespace: biological_process +def: "The iodination of peptidyl-thyronine, formed from tyrosine." [RESID:AA0177, RESID:AA0178] +xref: RESID:AA0177 +xref: RESID:AA0178 +is_a: GO:0018077 ! protein iodination +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018079 +name: protein halogenation +namespace: biological_process +def: "The addition of a halogen to a protein amino acid." [GOC:ai] +synonym: "protein amino acid halogenation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0070276 ! halogen metabolic process + +[Term] +id: GO:0018080 +name: peptidyl-tryptophan bromination +namespace: biological_process +def: "The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan." [RESID:AA0179] +xref: RESID:AA0179 +is_a: GO:0018073 ! protein bromination +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0018081 +name: peptide cross-linking via lanthionine or 3-methyl-lanthionine +namespace: biological_process +def: "The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process." [ISBN:0198547684, RESID:AA0110, RESID:AA0111, RESID:AA0112] +synonym: "peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine" EXACT [] +synonym: "peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine" EXACT [] +xref: RESID:AA0110 +xref: RESID:AA0111 +xref: RESID:AA0112 +is_a: GO:0018149 ! peptide cross-linking + +[Term] +id: GO:0018082 +name: peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine +namespace: biological_process +def: "The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine." [RESID:AA0182] +synonym: "peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine" EXACT [] +synonym: "peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine" EXACT [] +synonym: "peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine" EXACT [] +xref: RESID:AA0182 +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018083 +name: peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine +namespace: biological_process +def: "The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases." [RESID:AA0185] +synonym: "peptidyl-L-3-oxoalanine anabolism from peptidyl-cysteine or peptidyl-serine" EXACT [] +synonym: "peptidyl-L-3-oxoalanine formation from peptidyl-cysteine or peptidyl-serine" EXACT [] +synonym: "peptidyl-L-3-oxoalanine synthesis from peptidyl-cysteine or peptidyl-serine" EXACT [] +xref: RESID:AA0185 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018084 +name: peptidyl-lactic acid biosynthetic process from peptidyl-serine +namespace: biological_process +def: "The modification of N-terminal peptidyl-serine to lactic acid." [RESID:AA0186] +synonym: "peptidyl-lactic acid anabolism from peptidyl-serine" EXACT [] +synonym: "peptidyl-lactic acid formation from peptidyl-serine" EXACT [] +synonym: "peptidyl-lactic acid synthesis from peptidyl-serine" EXACT [] +xref: RESID:AA0186 +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018085 +name: peptidyl-L-amino acid racemization +namespace: biological_process +def: "The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid." [GOC:ma] +is_a: GO:0018193 ! peptidyl-amino acid modification +is_a: GO:0018366 ! chiral amino acid racemization + +[Term] +id: GO:0018086 +name: obsolete alanine racemization +namespace: biological_process +alt_id: GO:0018368 +def: "OBSOLETE. (Was not defined before being made obsolete)." [RESID:AA0191] +comment: This term was made obsolete because it was replaced with more appropriate terms. +synonym: "alanine racemization" EXACT [] +is_obsolete: true +consider: GO:0019122 + +[Term] +id: GO:0018091 +name: peptidyl-asparagine racemization +namespace: biological_process +alt_id: GO:0018373 +alt_id: GO:0019127 +def: "The racemization of peptidyl-asparagine." [RESID:AA0196] +xref: RESID:AA0196 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018094 +name: protein polyglycylation +namespace: biological_process +def: "The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid." [RESID:AA0201] +xref: RESID:AA0201 +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018095 +name: protein polyglutamylation +namespace: biological_process +def: "The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid." [RESID:AA0202] +xref: RESID:AA0202 +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018096 +name: peptide cross-linking via S-(2-aminovinyl)-D-cysteine +namespace: biological_process +def: "The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine." [RESID:AA0204] +xref: RESID:AA0204 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018097 +name: protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine +namespace: biological_process +def: "The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine." [RESID:AA0207] +synonym: "protein amino acid cinnamylation" BROAD [] +xref: RESID:AA0207 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0018101 +name: protein citrullination +namespace: biological_process +def: "The hydrolysis of peptidyl-arginine to form peptidyl-citrulline." [PMID:23175390, RESID:AA0214] +comment: Citrullination is distinct from the formation of the free amino acid citrulline (e.g. as part of the urea cycle). +synonym: "deimination" EXACT [Wikipedia:Citrullination] +synonym: "peptidyl-citrulline anabolism from peptidyl-arginine" EXACT [] +synonym: "peptidyl-citrulline biosynthetic process from peptidyl-arginine" EXACT [RESID:AA0214] +synonym: "peptidyl-citrulline formation from peptidyl-arginine" EXACT [] +synonym: "peptidyl-citrulline synthesis from peptidyl-arginine" EXACT [] +xref: RESID:AA0214 +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0018102 +name: peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine +namespace: biological_process +def: "The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine." [RESID:AA0215] +xref: RESID:AA0215 +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0030961 ! peptidyl-arginine hydroxylation + +[Term] +id: GO:0018103 +name: protein C-linked glycosylation +namespace: biological_process +def: "A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom." [GOC:pr, PMID:7947762, RESID:AA0217] +synonym: "protein amino acid C-linked glycosylation" EXACT [GOC:bf] +xref: RESID:AA0217 +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0018104 +name: peptidoglycan-protein cross-linking +namespace: biological_process +def: "The process of covalently linking peptidoglycan (murein) to proteins." [GOC:jsg] +is_a: GO:0009252 ! peptidoglycan biosynthetic process + +[Term] +id: GO:0018105 +name: peptidyl-serine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine." [RESID:AA0037] +xref: RESID:AA0037 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018106 +name: peptidyl-histidine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)." [RESID:AA0035, RESID:AA0036] +xref: RESID:AA0035 +xref: RESID:AA0036 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018107 +name: peptidyl-threonine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [RESID:AA0038] +xref: RESID:AA0038 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018108 +name: peptidyl-tyrosine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine." [RESID:AA0039] +xref: RESID:AA0039 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018109 +name: peptidyl-arginine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine." [RESID:AA0222] +xref: RESID:AA0222 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0018110 +name: histone arginine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+)." [GOC:mah] +synonym: "histone-arginine kinase activity" EXACT [] +xref: EC:2.7.3 +is_a: GO:0004054 ! arginine kinase activity +is_a: GO:0035173 ! histone kinase activity +relationship: part_of GO:0018109 ! peptidyl-arginine phosphorylation + +[Term] +id: GO:0018111 +name: methionine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine = D-methionine." [EC:5.1.1.2, RHEA:12492] +xref: EC:5.1.1.2 +xref: KEGG_REACTION:R00655 +xref: MetaCyc:METHIONINE-RACEMASE-RXN +xref: RHEA:12492 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0018112 +name: proline racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline = D-proline." [EC:5.1.1.4, RHEA:10680] +xref: EC:5.1.1.4 +xref: KEGG_REACTION:R01255 +xref: MetaCyc:PROLINE-RACEMASE-RXN +xref: RHEA:10680 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0018113 +name: lysine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine = D-lysine." [EC:5.1.1.5] +xref: EC:5.1.1.5 +xref: MetaCyc:LYSINE-RACEMASE-RXN +xref: RHEA:22864 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0018114 +name: threonine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine = D-threonine." [EC:5.1.1.6, RHEA:13913] +xref: EC:5.1.1.6 +xref: KEGG_REACTION:R01467 +xref: MetaCyc:THREONINE-RACEMASE-RXN +xref: RHEA:13913 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0018115 +name: peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine." [PMID:7797461, RESID:AA0223] +synonym: "peptidyl-S-diphytanylglycerol diether-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-diphytanylglycerol diether-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-diphytanylglycerol diether-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0223 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018116 +name: peptidyl-lysine adenylylation +namespace: biological_process +def: "The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine." [RESID:AA0227] +synonym: "peptidyl-lysine adenylation" EXACT [] +xref: RESID:AA0227 +is_a: GO:0018117 ! protein adenylylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018117 +name: protein adenylylation +namespace: biological_process +alt_id: GO:0018176 +def: "The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid." [GOC:ai, GOC:jsg, GOC:sart, PMID:21607083] +synonym: "protein adenylation" EXACT [] +synonym: "protein amino acid adenylylation" EXACT [GOC:bf] +synonym: "protein AMPylation" EXACT [GOC:jsg, GOC:sart, PMID:21607083] +is_a: GO:0018175 ! protein nucleotidylation + +[Term] +id: GO:0018118 +name: peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide." [RESID:AA0229] +synonym: "peptidyl-L-cysteine glutathione disulfide anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine glutathione disulfide formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine glutathione disulfide synthesis from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine glutathione disulphide biosynthesis from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine glutathione disulphide biosynthetic process from peptidyl-cysteine" EXACT [] +xref: RESID:AA0229 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018119 +name: peptidyl-cysteine S-nitrosylation +namespace: biological_process +def: "The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine." [RESID:AA0230] +synonym: "protein S-nitrosylation" EXACT [PMID:20972426] +synonym: "S-nitrosylation" EXACT [PMID:20972426] +xref: RESID:AA0230 +is_a: GO:0017014 ! protein nitrosylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018120 +name: peptidyl-arginine ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine." [RESID:AA0168] +xref: RESID:AA0168 +is_a: GO:0006471 ! protein ADP-ribosylation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0018121 +name: NAD(P)-asparagine ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine." [EC:2.4.2.-] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0018122 +name: peptidyl-asparagine ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine." [RESID:AA0231] +xref: RESID:AA0231 +is_a: GO:0006471 ! protein ADP-ribosylation +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018123 +name: peptidyl-cysteine ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine." [RESID:AA0169] +xref: RESID:AA0169 +is_a: GO:0006471 ! protein ADP-ribosylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018124 +name: peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone +namespace: biological_process +def: "The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue." [RESID:AA0233] +xref: RESID:AA0233 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018125 +name: peptidyl-cysteine methylation +namespace: biological_process +def: "The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine." [RESID:AA0234] +xref: RESID:AA0234 +is_a: GO:0006479 ! protein methylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018126 +name: protein hydroxylation +namespace: biological_process +def: "The addition of a hydroxy group to a protein amino acid." [GOC:ai] +synonym: "protein amino acid hydroxylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018127 +name: NAD(P)-serine ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine." [EC:2.4.2.-] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0018128 +name: obsolete peptidyl-serine cyclase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists. +synonym: "peptidyl-serine cyclase activity" EXACT [] +xref: EC:4.2.1 +is_obsolete: true + +[Term] +id: GO:0018129 +name: peptidyl-oxazoline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reduction of a peptide-linked oxazoline to oxazole." [GOC:mah, PMID:19058272] +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018130 +name: heterocycle biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] +synonym: "heterocycle anabolism" EXACT [] +synonym: "heterocycle biosynthesis" EXACT [] +synonym: "heterocycle formation" EXACT [] +synonym: "heterocycle synthesis" EXACT [] +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0018131 +name: oxazole or thiazole biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position." [GOC:curators] +synonym: "oxazole or thiazole anabolism" EXACT [] +synonym: "oxazole or thiazole biosynthesis" EXACT [] +synonym: "oxazole or thiazole formation" EXACT [] +synonym: "oxazole or thiazole synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046484 ! oxazole or thiazole metabolic process + +[Term] +id: GO:0018132 +name: peptide cross-linking via L-cysteine oxazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [PMID:8895467, RESID:AA0238] +xref: RESID:AA0238 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018133 +name: peptide cross-linking via L-cysteine oxazolinecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue." [RESID:AA0239] +xref: RESID:AA0239 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018134 +name: peptide cross-linking via glycine oxazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0240] +xref: RESID:AA0240 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018135 +name: obsolete peptidyl-cysteine cyclase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists. +synonym: "peptidyl-cysteine cyclase activity" EXACT [] +xref: EC:4.2.1 +is_obsolete: true + +[Term] +id: GO:0018136 +name: peptidyl-thiazoline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reduction of a peptide-linked thiazoline to thiazole." [GOC:mah, PMID:19058272] +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018137 +name: peptide cross-linking via glycine thiazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0241] +xref: RESID:AA0241 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018138 +name: peptide cross-linking via L-serine thiazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0242] +xref: RESID:AA0242 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018139 +name: peptide cross-linking via L-phenylalanine thiazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0243] +xref: RESID:AA0243 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0018140 +name: peptide cross-linking via L-cysteine thiazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0244] +xref: RESID:AA0244 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018141 +name: peptide cross-linking via L-lysine thiazolecarboxylic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [RESID:AA0245] +xref: RESID:AA0245 +is_a: GO:0018157 ! peptide cross-linking via an oxazole or thiazole +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018142 +name: protein-DNA covalent cross-linking +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a protein." [GOC:ma] +synonym: "DNA-protein covalent cross-linking" EXACT [GOC:mah] +is_a: GO:0018143 ! nucleic acid-protein covalent cross-linking + +[Term] +id: GO:0018143 +name: nucleic acid-protein covalent cross-linking +namespace: biological_process +def: "The formation of a covalent cross-link between a nucleic acid and a protein." [GOC:ma] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018144 +name: RNA-protein covalent cross-linking +namespace: biological_process +def: "The formation of a covalent cross-link between RNA and a protein." [GOC:ma] +is_a: GO:0018143 ! nucleic acid-protein covalent cross-linking + +[Term] +id: GO:0018145 +name: protein-DNA covalent cross-linking via peptidyl-serine +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine." [RESID:AA0246] +synonym: "DNA-protein covalent cross-linking via peptidyl-serine" EXACT [GOC:mah] +xref: RESID:AA0246 +is_a: GO:0018142 ! protein-DNA covalent cross-linking +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018146 +name: keratan sulfate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues." [ISBN:0198547684, RESID:AA0247] +synonym: "keratan sulfate anabolism" EXACT [] +synonym: "keratan sulfate biosynthesis" EXACT [] +synonym: "keratan sulfate formation" EXACT [] +synonym: "keratan sulfate synthesis" EXACT [] +synonym: "keratan sulphate biosynthesis" EXACT [] +synonym: "keratan sulphate biosynthetic process" EXACT [] +xref: RESID:AA0247 +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0042339 ! keratan sulfate metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0018147 +name: molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) +namespace: biological_process +def: "The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)." [RESID:AA0248] +xref: RESID:AA0248 +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex +is_a: GO:0050844 ! peptidyl-selenocysteine modification + +[Term] +id: GO:0018148 +name: RNA-protein covalent cross-linking via peptidyl-tyrosine +namespace: biological_process +def: "The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine." [RESID:AA0249] +xref: RESID:AA0249 +is_a: GO:0018144 ! RNA-protein covalent cross-linking +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018149 +name: peptide cross-linking +namespace: biological_process +def: "The formation of a covalent cross-link between or within protein chains." [GOC:jsg] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018150 +name: peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine +namespace: biological_process +def: "The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link." [RESID:AA0250] +xref: RESID:AA0250 +is_a: GO:0018151 ! peptide cross-linking via L-histidyl-L-tyrosine + +[Term] +id: GO:0018151 +name: peptide cross-linking via L-histidyl-L-tyrosine +namespace: biological_process +def: "The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link." [GOC:ai] +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018152 +name: peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine +namespace: biological_process +def: "The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link." [RESID:AA0270] +xref: RESID:AA0270 +is_a: GO:0018151 ! peptide cross-linking via L-histidyl-L-tyrosine + +[Term] +id: GO:0018153 +name: isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine +namespace: biological_process +def: "The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine." [RESID:AA0124] +xref: RESID:AA0124 +is_a: GO:0018199 ! peptidyl-glutamine modification +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018262 ! isopeptide cross-linking + +[Term] +id: GO:0018154 +name: peptide cross-linking via (2R,6R)-lanthionine +namespace: biological_process +def: "The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine)." [RESID:AA0110] +xref: RESID:AA0110 +is_a: GO:0018081 ! peptide cross-linking via lanthionine or 3-methyl-lanthionine +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018155 +name: peptide cross-linking via sn-(2S,6R)-lanthionine +namespace: biological_process +def: "The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione)." [RESID:AA0111] +xref: RESID:AA0111 +is_a: GO:0018081 ! peptide cross-linking via lanthionine or 3-methyl-lanthionine +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018156 +name: peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine +namespace: biological_process +def: "The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine)." [RESID:AA0112] +xref: RESID:AA0112 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018157 +name: peptide cross-linking via an oxazole or thiazole +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation." [GOC:jsg] +synonym: "peptide heterocycle biosynthesis" RELATED [GOC:mah] +synonym: "peptide heterocycle biosynthetic process" RELATED [GOC:mah] +synonym: "peptide heterocycle formation" RELATED [GOC:mah] +synonym: "peptide heterocycle synthesis" RELATED [GOC:mah] +is_a: GO:0018131 ! oxazole or thiazole biosynthetic process +is_a: GO:0018149 ! peptide cross-linking + +[Term] +id: GO:0018158 +name: protein oxidation +namespace: biological_process +def: "The modification of a protein amino acid by oxidation." [GOC:ai] +synonym: "protein amino acid oxidation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0018159 +name: peptidyl-methionine oxidation +namespace: biological_process +def: "The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone." [RESID:AA0251] +xref: RESID:AA0251 +is_a: GO:0018158 ! protein oxidation +is_a: GO:0018206 ! peptidyl-methionine modification + +[Term] +id: GO:0018160 +name: peptidyl-pyrromethane cofactor linkage +namespace: biological_process +alt_id: GO:0018354 +alt_id: GO:0033035 +def: "The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine." [RESID:AA0252] +synonym: "dipyrromethane cofactor binding" RELATED [GOC:jsg] +synonym: "peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine" EXACT [GOC:jsg] +xref: RESID:AA0252 +is_a: GO:0018065 ! protein-cofactor linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018161 +name: dipyrrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group." [http://www.chem.qmw.ac.uk/iupac/class/tetpy.html#03] +synonym: "dipyrrin anabolism" EXACT [] +synonym: "dipyrrin biosynthesis" EXACT [] +synonym: "dipyrrin formation" EXACT [] +synonym: "dipyrrin synthesis" EXACT [] +synonym: "dipyrromethane biosynthesis" EXACT [] +synonym: "dipyrromethane biosynthetic process" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0046453 ! dipyrrin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0018162 +name: peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine +namespace: biological_process +def: "The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine." [RESID:AA0253] +xref: RESID:AA0253 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018163 +name: protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine." [RESID:AA0254] +synonym: "DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine" EXACT [GOC:mah] +xref: RESID:AA0254 +is_a: GO:0045327 ! protein-DNA covalent cross-linking via peptidyl-tyrosine + +[Term] +id: GO:0018164 +name: protein-DNA covalent cross-linking via peptidyl-threonine +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine." [RESID:AA0255] +synonym: "DNA-protein covalent cross-linking via peptidyl-threonine" EXACT [GOC:mah] +xref: RESID:AA0255 +is_a: GO:0018142 ! protein-DNA covalent cross-linking +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018165 +name: peptidyl-tyrosine uridylylation +namespace: biological_process +def: "The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase." [RESID:AA0256] +xref: RESID:AA0256 +is_a: GO:0018177 ! protein uridylylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018166 +name: C-terminal protein-tyrosinylation +namespace: biological_process +def: "The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase." [RESID:AA0257] +comment: See also the molecular function term 'tubulin-tyrosine ligase activity ; GO:0004835'. +xref: RESID:AA0257 +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018322 ! protein tyrosinylation +is_a: GO:0018410 ! C-terminal protein amino acid modification + +[Term] +id: GO:0018167 +name: protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine +namespace: biological_process +def: "The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine." [RESID:AA0259] +xref: RESID:AA0259 +is_a: GO:0017011 ! protein-phycoerythrobilin linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018168 +name: protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine +namespace: biological_process +def: "The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine." [RESID:AA0132] +xref: RESID:AA0132 +is_a: GO:0017011 ! protein-phycoerythrobilin linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018169 +name: ribosomal S6-glutamic acid ligase activity +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6." [GOC:mah, PMID:2570347] +is_a: GO:0070739 ! protein-glutamic acid ligase activity + +[Term] +id: GO:0018170 +name: C-terminal peptidyl-polyglutamic acid amidation +namespace: biological_process +def: "The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus." [RESID:AA0261] +xref: RESID:AA0261 +is_a: GO:0018040 ! C-terminal peptidyl-glutamic acid amidation +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018171 +name: peptidyl-cysteine oxidation +namespace: biological_process +def: "The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid." [PMID:9586994, RESID:AA0205, RESID:AA0262] +xref: RESID:AA0205 +xref: RESID:AA0262 +is_a: GO:0018158 ! protein oxidation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018172 +name: peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine +namespace: biological_process +def: "The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine." [RESID:AA0263] +synonym: "peptidyl-L-3',4',5'-trihydroxyphenylalanine anabolism from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-3',4',5'-trihydroxyphenylalanine formation from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-L-3',4',5'-trihydroxyphenylalanine synthesis from peptidyl-tyrosine" EXACT [] +xref: RESID:AA0263 +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018336 ! peptidyl-tyrosine hydroxylation + +[Term] +id: GO:0018173 +name: peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine." [http://www.uni-marburg.de/mpi/thauer/thauer_res.html, RESID:AA0265] +synonym: "peptidyl-1-thioglycine anabolism from peptidyl-glycine" EXACT [] +synonym: "peptidyl-1-thioglycine formation from peptidyl-glycine" EXACT [] +synonym: "peptidyl-1-thioglycine synthesis from peptidyl-glycine" EXACT [] +xref: RESID:AA0265 +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +relationship: part_of GO:0015011 ! nickel-tetrapyrrole coenzyme metabolic process + +[Term] +id: GO:0018174 +name: protein-heme P460 linkage +namespace: biological_process +def: "The linkage of protein to heme P460." [RESID:AA0266, RESID:AA0271] +synonym: "protein-haem P460 linkage" EXACT [] +xref: RESID:AA0266 +xref: RESID:AA0271 +is_a: GO:0017003 ! protein-heme linkage +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0018175 +name: protein nucleotidylation +namespace: biological_process +def: "The addition of a nucleotide to a protein amino acid." [GOC:ai] +synonym: "protein amino acid nucleotidylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018177 +name: protein uridylylation +namespace: biological_process +def: "The addition of phospho-uridine to a protein amino acid." [GOC:jsg] +synonym: "protein amino acid uridylylation" EXACT [GOC:bf] +is_a: GO:0018175 ! protein nucleotidylation + +[Term] +id: GO:0018178 +name: peptidyl-threonine adenylylation +namespace: biological_process +def: "The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine." [RESID:AA0267] +synonym: "peptidyl-threonine adenylation" EXACT [] +xref: RESID:AA0267 +is_a: GO:0018117 ! protein adenylylation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018179 +name: obsolete peptidyl-cysteine desulfurization +namespace: biological_process +def: "OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate." [RESID:AA0269] +comment: This term was made obsolete because to does not correspond to a real process. +synonym: "peptidyl-cysteine desulfurization" EXACT [] +synonym: "peptidyl-cysteine desulphurization" EXACT [] +xref: RESID:AA0269 +is_obsolete: true + +[Term] +id: GO:0018180 +name: protein desulfurization +namespace: biological_process +def: "The removal of a sulfur group from a protein amino acid." [GOC:ai] +synonym: "protein amino acid desulfurisation" EXACT [] +synonym: "protein amino acid desulfurization" EXACT [GOC:bf] +synonym: "protein amino acid desulphurisation" EXACT [] +synonym: "protein amino acid desulphurization" EXACT [] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018181 +name: peptidyl-arginine C5-methylation +namespace: biological_process +def: "The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine." [GOC:bf, http://www.uni-marburg.de/mpi/thauer/thauer_res.html, RESID:AA0272] +synonym: "peptidyl-arginine 5-methylation" EXACT [] +xref: RESID:AA0272 +is_a: GO:0035245 ! peptidyl-arginine C-methylation + +[Term] +id: GO:0018182 +name: protein-heme linkage via 3'-L-histidine +namespace: biological_process +def: "The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine)." [RESID:AA0276] +synonym: "protein-haem linkage via 3'-L-histidine" EXACT [] +xref: RESID:AA0276 +is_a: GO:0017003 ! protein-heme linkage +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018183 +name: obsolete enzyme active site formation via S-selenyl-L-cysteine +namespace: biological_process +def: "OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine." [RESID:AA0277] +comment: This term was made obsolete because this structure does not exist. +synonym: "enzyme active site formation via S-selenyl-L-cysteine" EXACT [] +is_obsolete: true + +[Term] +id: GO:0018184 +name: protein polyamination +namespace: biological_process +def: "The modification of a protein amino acid by polyamination." [GOC:ai] +synonym: "protein amino acid polyamination" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018185 +name: poly-N-methyl-propylamination +namespace: biological_process +def: "The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin." [RESID:AA0278] +xref: RESID:AA0278 +is_a: GO:0018184 ! protein polyamination +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018186 +name: peroxidase-heme linkage +namespace: biological_process +def: "The covalent linkage of heme to peroxidase." [RESID:AA0279, RESID:AA0280] +synonym: "peroxidase-haem linkage" EXACT [] +xref: RESID:AA0279 +xref: RESID:AA0280 +is_a: GO:0017003 ! protein-heme linkage +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0018187 +name: molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide +namespace: biological_process +def: "The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide." [RESID:AA0281] +xref: RESID:AA0281 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex + +[Term] +id: GO:0018188 +name: peptidyl-proline di-hydroxylation +namespace: biological_process +def: "The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline." [RESID:AA0282] +xref: RESID:AA0282 +is_a: GO:0019511 ! peptidyl-proline hydroxylation + +[Term] +id: GO:0018189 +name: pyrroloquinoline quinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed." [PMID:7665488, RESID:AA0283] +synonym: "coenzyme pyrroloquinoline-quinone biosynthesis" EXACT [] +synonym: "coenzyme pyrroloquinoline-quinone biosynthetic process" EXACT [] +synonym: "PQQ biosynthesis" EXACT [] +synonym: "PQQ biosynthetic process" EXACT [] +synonym: "pyrroloquinoline quinone anabolism" EXACT [] +synonym: "pyrroloquinoline quinone biosynthesis" EXACT [] +synonym: "pyrroloquinoline quinone formation" EXACT [] +synonym: "pyrroloquinoline quinone synthesis" EXACT [] +synonym: "pyrroloquinoline-quinone biosynthesis" EXACT [] +synonym: "pyrroloquinoline-quinone biosynthetic process" EXACT [] +xref: RESID:AA0283 +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process + +[Term] +id: GO:0018190 +name: protein octanoylation +namespace: biological_process +def: "The modification of a protein amino acid by formation of an ester or amide with octanoic acid." [GOC:jsg] +synonym: "protein amino acid octanoylation" EXACT [GOC:bf] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0018191 +name: peptidyl-serine octanoylation +namespace: biological_process +def: "The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin." [PMID:10604470, RESID:AA0290] +xref: RESID:AA0290 +is_a: GO:0018190 ! protein octanoylation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018192 +name: enzyme active site formation via cysteine modification to L-cysteine persulfide +namespace: biological_process +def: "The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide." [PMID:11592406, RESID:AA0269] +synonym: "enzyme active site formation via L-cysteine persulphide" EXACT [] +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0098822 ! peptidyl-cysteine modification to L-cysteine persulfide + +[Term] +id: GO:0018193 +name: peptidyl-amino acid modification +namespace: biological_process +def: "The alteration of an amino acid residue in a peptide." [GOC:mah] +subset: goslim_yeast +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018194 +name: peptidyl-alanine modification +namespace: biological_process +def: "The modification of peptidyl-alanine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018195 +name: peptidyl-arginine modification +namespace: biological_process +def: "The modification of peptidyl-arginine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018196 +name: peptidyl-asparagine modification +namespace: biological_process +def: "The modification of peptidyl-asparagine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018197 +name: peptidyl-aspartic acid modification +namespace: biological_process +def: "The modification of peptidyl-aspartic acid." [GOC:ma] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018198 +name: peptidyl-cysteine modification +namespace: biological_process +def: "The modification of peptidyl-cysteine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018199 +name: peptidyl-glutamine modification +namespace: biological_process +def: "The modification of peptidyl-glutamine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018200 +name: peptidyl-glutamic acid modification +namespace: biological_process +def: "The modification of peptidyl-glutamic acid." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018201 +name: peptidyl-glycine modification +namespace: biological_process +def: "The modification of peptidyl-glycine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018202 +name: peptidyl-histidine modification +namespace: biological_process +def: "The modification of peptidyl-histidine." [GOC:ma] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018203 +name: peptidyl-isoleucine modification +namespace: biological_process +def: "The modification of peptidyl-isoleucine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018204 +name: peptidyl-leucine modification +namespace: biological_process +def: "The modification of peptidyl-leucine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018205 +name: peptidyl-lysine modification +namespace: biological_process +def: "The modification of peptidyl-lysine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018206 +name: peptidyl-methionine modification +namespace: biological_process +def: "The modification of peptidyl-methionine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018207 +name: peptidyl-phenylalanine modification +namespace: biological_process +def: "The modification of peptidyl-phenylalanine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018208 +name: peptidyl-proline modification +namespace: biological_process +def: "The modification of peptidyl-proline." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018209 +name: peptidyl-serine modification +namespace: biological_process +def: "The modification of peptidyl-serine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018210 +name: peptidyl-threonine modification +namespace: biological_process +def: "The modification of peptidyl-threonine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018211 +name: peptidyl-tryptophan modification +namespace: biological_process +def: "The chemical alteration of a tryptophan residue in a peptide." [GOC:isa_complete] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018212 +name: peptidyl-tyrosine modification +namespace: biological_process +def: "The modification of peptidyl-tyrosine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018213 +name: peptidyl-valine modification +namespace: biological_process +def: "The modification of peptidyl-valine." [GOC:go_curators] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0018214 +name: protein carboxylation +namespace: biological_process +def: "The addition of a carboxy group to a protein amino acid." [GOC:ai] +synonym: "protein amino acid carboxylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018215 +name: protein phosphopantetheinylation +namespace: biological_process +def: "The modification of a protein amino acid by phosphopantetheinylation." [GOC:ai] +synonym: "protein amino acid phosphopantetheinylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018216 +name: peptidyl-arginine methylation +namespace: biological_process +alt_id: GO:0018017 +def: "The addition of a methyl group to an arginine residue in a protein." [GOC:mah] +is_a: GO:0006479 ! protein methylation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0018217 +name: peptidyl-aspartic acid phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-aspartic acid." [GOC:jl] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0018218 +name: peptidyl-cysteine phosphorylation +namespace: biological_process +def: "The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine." [RESID:AA0034] +xref: RESID:AA0034 +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018219 +name: peptidyl-cysteine S-acetylation +namespace: biological_process +def: "The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine." [RESID:AA0056] +xref: RESID:AA0056 +is_a: GO:0018533 ! peptidyl-cysteine acetylation + +[Term] +id: GO:0018220 +name: peptidyl-threonine palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine." [RESID:AA0079] +comment: Palmitoylation of a non-terminal threonine residue always occurs on an oxygen (O) atom. +synonym: "peptidyl-threonine O-palmitoylation" EXACT [GOC:jsg] +xref: RESID:AA0079 +is_a: GO:0018210 ! peptidyl-threonine modification +is_a: GO:0018345 ! protein palmitoylation + +[Term] +id: GO:0018221 +name: peptidyl-serine palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine." [RESID:AA0080] +comment: Palmitoylation of a non-terminal serine residue always occurs on an oxygen (O) atom. +synonym: "peptidyl-serine O-palmitoylation" EXACT [GOC:jsg] +xref: RESID:AA0080 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018345 ! protein palmitoylation + +[Term] +id: GO:0018222 +name: peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide." [RESID:AA0101] +synonym: "peptidyl-L-cysteine methyl disulfide anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl disulfide formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl disulfide synthesis from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl disulphide biosynthesis from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl disulphide biosynthetic process from peptidyl-cysteine" EXACT [] +xref: RESID:AA0101 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018226 +name: peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic." [RESID:AA0102] +synonym: "peptidyl-S-farnesyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-farnesyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-farnesyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0102 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018343 ! protein farnesylation + +[Term] +id: GO:0018227 +name: peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine." [RESID:AA0103] +synonym: "peptidyl-S-12-hydroxyfarnesyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-12-hydroxyfarnesyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0103 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018343 ! protein farnesylation + +[Term] +id: GO:0018228 +name: peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification." [RESID:AA0104] +synonym: "peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0104 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018344 ! protein geranylgeranylation + +[Term] +id: GO:0018229 +name: peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester." [RESID:AA0105] +synonym: "peptidyl-L-cysteine methyl ester anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl ester formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-L-cysteine methyl ester synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0105 +is_a: GO:0006481 ! C-terminal protein methylation +is_a: GO:0018351 ! peptidyl-cysteine esterification + +[Term] +id: GO:0018230 +name: peptidyl-L-cysteine S-palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine." [RESID:AA0106] +comment: Palmitoylation of a non-terminal cysteine residue always occurs on a sulfur (S) atom. +synonym: "peptidyl-cysteine S-palmitoylation" EXACT [] +synonym: "peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0106 +is_a: GO:0018231 ! peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine +is_a: GO:0018345 ! protein palmitoylation + +[Term] +id: GO:0018231 +name: peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids." [RESID:AA0107] +synonym: "peptidyl-S-diacylglycerol-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-diacylglycerol-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-diacylglycerol-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0107 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018232 +name: peptide cross-linking via S-(L-isoglutamyl)-L-cysteine +namespace: biological_process +def: "The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link." [RESID:AA0108] +xref: RESID:AA0108 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0018233 +name: peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine +namespace: biological_process +def: "The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link." [RESID:AA0109] +xref: RESID:AA0109 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0018234 +name: peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine +namespace: biological_process +def: "The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase." [RESID:AA0113] +xref: RESID:AA0113 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018235 +name: peptidyl-lysine carboxylation +namespace: biological_process +def: "The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine." [RESID:AA0114] +xref: RESID:AA0114 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018214 ! protein carboxylation + +[Term] +id: GO:0018237 +name: urease activator activity +namespace: molecular_function +def: "Increases the activity of urease by promoting the incorporation of nickel into the active site." [GOC:mah, PMID:16244137] +synonym: "urease activase activity" EXACT [] +is_a: GO:0008047 ! enzyme activator activity + +[Term] +id: GO:0018238 +name: peptidyl-lysine carboxyethylation +namespace: biological_process +alt_id: GO:0018239 +def: "The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine." [RESID:AA0115] +synonym: "protein amino acid carboxyethylation" EXACT [] +xref: RESID:AA0115 +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018240 +name: protein S-linked glycosylation via cysteine +namespace: biological_process +def: "The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine." [RESID:AA0152] +synonym: "protein amino acid S-linked glycosylation via cysteine" EXACT [GOC:bf] +xref: RESID:AA0152 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018280 ! protein S-linked glycosylation + +[Term] +id: GO:0018241 +name: protein O-linked glycosylation via hydroxylysine +namespace: biological_process +def: "The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine." [RESID:AA0153] +synonym: "protein amino acid O-linked glycosylation via hydroxylysine" EXACT [GOC:bf] +xref: RESID:AA0153 +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018242 +name: protein O-linked glycosylation via serine +namespace: biological_process +def: "The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine." [RESID:AA0154] +synonym: "protein amino acid O-linked glycosylation via serine" EXACT [GOC:bf] +xref: RESID:AA0154 +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018243 +name: protein O-linked glycosylation via threonine +namespace: biological_process +def: "The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine." [RESID:AA0155] +synonym: "protein amino acid O-linked glycosylation via threonine" EXACT [GOC:bf] +xref: RESID:AA0155 +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018244 +name: protein N-linked glycosylation via tryptophan +namespace: biological_process +def: "The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue." [RESID:AA0156] +synonym: "protein amino acid N-linked glycosylation via tryptophan" EXACT [GOC:bf] +xref: RESID:AA0156 +is_a: GO:0006487 ! protein N-linked glycosylation +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0018245 +name: protein O-linked glycosylation via tyrosine +namespace: biological_process +def: "The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen." [RESID:AA0157] +synonym: "protein amino acid O-linked glycosylation via tyrosine" EXACT [GOC:bf] +xref: RESID:AA0157 +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018246 +name: protein-coenzyme A linkage +namespace: biological_process +def: "The formation of a linkage between a protein amino acid and coenzyme A." [GOC:mah] +is_a: GO:0018065 ! protein-cofactor linkage + +[Term] +id: GO:0018247 +name: protein-phosphoribosyl dephospho-coenzyme A linkage +namespace: biological_process +def: "The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position." [RESID:AA0167] +xref: RESID:AA0167 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018246 ! protein-coenzyme A linkage + +[Term] +id: GO:0018248 +name: enzyme active site formation via peptidyl cysteine sulfation +namespace: biological_process +def: "The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine." [RESID:AA0171] +synonym: "enzyme active site formation via S-sulpho-L-cysteine" EXACT [] +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0098824 ! peptidyl-cysteine sulfation + +[Term] +id: GO:0018249 +name: protein dehydration +namespace: biological_process +def: "The removal of a water group from a protein amino acid." [GOC:ai] +synonym: "protein amino acid dehydration" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018250 +name: peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine +namespace: biological_process +def: "The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG." [RESID:AA0181] +synonym: "peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine" EXACT [] +synonym: "peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine" EXACT [] +synonym: "peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine" EXACT [] +xref: RESID:AA0181 +is_a: GO:0018194 ! peptidyl-alanine modification +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018249 ! protein dehydration +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0018251 +name: peptidyl-tyrosine dehydrogenation +namespace: biological_process +def: "The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues." [RESID:AA0183] +comment: See also the biological process terms 'peptide cross-linking via L-seryl-5-imidazolinone glycine ; GO:0018252' and 'peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine ; GO:0019729'. +xref: RESID:AA0183 +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018249 ! protein dehydration + +[Term] +id: GO:0018252 +name: peptide cross-linking via L-seryl-5-imidazolinone glycine +namespace: biological_process +def: "The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons." [RESID:AA0184] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via L-seryl-5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via L-seryl-5-imidazolinone glycine" EXACT [] +xref: RESID:AA0184 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0018253 +name: peptide cross-linking via 5-imidazolinone glycine +namespace: biological_process +def: "The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde." [RESID:AA0184, RESID:AA0187, RESID:AA0188] +synonym: "biosynthesis of protein-protein cross-link via 5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via 5-imidazolinone glycine" EXACT [] +xref: RESID:AA0184 +xref: RESID:AA0187 +xref: RESID:AA0188 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018254 +name: peptidyl-tyrosine adenylylation +namespace: biological_process +def: "The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine." [RESID:AA0203] +synonym: "peptidyl-tyrosine adenylation" EXACT [] +xref: RESID:AA0203 +is_a: GO:0018117 ! protein adenylylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018255 +name: peptide cross-linking via S-glycyl-L-cysteine +namespace: biological_process +def: "The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins." [GOC:jh2, RESID:AA0206] +xref: RESID:AA0206 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018256 +name: protein formylation +namespace: biological_process +def: "The addition of a formyl group to a protein amino acid." [GOC:ai] +synonym: "protein amino acid formylation" EXACT [GOC:bf] +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0018257 +name: peptidyl-lysine formylation +namespace: biological_process +def: "The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine." [RESID:AA0211] +xref: RESID:AA0211 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018256 ! protein formylation + +[Term] +id: GO:0018258 +name: protein O-linked glycosylation via hydroxyproline +namespace: biological_process +def: "The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline." [RESID:AA0212] +synonym: "protein amino acid O-linked glycosylation via hydroxyproline" EXACT [GOC:bf] +xref: RESID:AA0212 +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0018259 +name: RNA-protein covalent cross-linking via peptidyl-serine +namespace: biological_process +def: "The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine." [RESID:AA0213] +xref: RESID:AA0213 +is_a: GO:0018144 ! RNA-protein covalent cross-linking +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018260 +name: protein guanylylation +namespace: biological_process +def: "The addition of phospho-guanosine to a protein amino acid." [GOC:ai] +synonym: "protein amino acid guanylylation" EXACT [GOC:bf] +is_a: GO:0018175 ! protein nucleotidylation + +[Term] +id: GO:0018261 +name: peptidyl-lysine guanylylation +namespace: biological_process +def: "The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine." [RESID:AA0228] +xref: RESID:AA0228 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018260 ! protein guanylylation + +[Term] +id: GO:0018262 +name: isopeptide cross-linking +namespace: biological_process +def: "The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon." [GOC:jsg] +is_a: GO:0018149 ! peptide cross-linking + +[Term] +id: GO:0018263 +name: isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine +namespace: biological_process +def: "The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine." [RESID:AA0216] +xref: RESID:AA0216 +is_a: GO:0018196 ! peptidyl-asparagine modification +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018262 ! isopeptide cross-linking + +[Term] +id: GO:0018264 +name: isopeptide cross-linking via N-(L-isoaspartyl)-glycine +namespace: biological_process +def: "The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine." [RESID:AA0126] +xref: RESID:AA0126 +is_a: GO:0018196 ! peptidyl-asparagine modification +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018262 ! isopeptide cross-linking + +[Term] +id: GO:0018265 +name: GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0158] +synonym: "GPI anchor anabolism via N-asparaginyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-asparaginyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-asparaginyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0158 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018266 +name: GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0159] +synonym: "GPI anchor anabolism via N-aspartyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-aspartyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-aspartyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0159 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0018267 +name: GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0160] +synonym: "GPI anchor anabolism via N-cysteinyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-cysteinyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-cysteinyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0160 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018268 +name: GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0161] +synonym: "GPI anchor anabolism via N-glycyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-glycyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-glycyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0161 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0018269 +name: GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0162] +synonym: "GPI anchor anabolism via N-seryl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-seryl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-seryl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0162 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018270 +name: GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0163] +synonym: "GPI anchor anabolism via N-alanyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-alanyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-alanyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0163 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0018271 +name: biotin-protein ligase activity +namespace: molecular_function +alt_id: GO:0000106 +def: "Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein." [GOC:mah] +synonym: "biotin-apoprotein ligase activity" EXACT [] +xref: EC:6.3.4 +xref: MetaCyc:BIOTINLIG-RXN +xref: Reactome:R-HSA-2993447 "HLCS biotinylates 6x(PCCA:PCCB)" +xref: Reactome:R-HSA-2993799 "HLCS biotinylates 6xMCCC1:6xMCCC2" +xref: Reactome:R-HSA-2993802 "HLCS biotinylates PC:Mn2+" +xref: Reactome:R-HSA-2993814 "HLCS biotinylates ACACA:Mn2+" +xref: Reactome:R-HSA-3323184 "Defective HLCS does not biotinylate ACACA:Mn2+" +xref: Reactome:R-HSA-4167511 "HLCS biotinylates ACACB" +xref: Reactome:R-HSA-9035987 "Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2" +xref: Reactome:R-HSA-9035988 "Defective HLCS does not biotinylate PC:Mn2+" +xref: Reactome:R-HSA-9035990 "Defective HLCS does not biotinylate 6x(PCCA:PCCB)" +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0018272 +name: protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine +namespace: biological_process +def: "The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine." [RESID:AA0119] +xref: RESID:AA0119 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018352 ! protein-pyridoxal-5-phosphate linkage + +[Term] +id: GO:0018273 +name: protein-chromophore linkage via peptidyl-N6-retinal-L-lysine +namespace: biological_process +def: "The modification of peptidyl-lysine to form N6-retinal-L-lysine." [RESID:AA0120] +xref: RESID:AA0120 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0018274 +name: peptide cross-linking via L-lysinoalanine +namespace: biological_process +def: "The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link." [RESID:AA0123] +xref: RESID:AA0123 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018275 +name: N-terminal peptidyl-cysteine acetylation +namespace: biological_process +alt_id: GO:0017191 +def: "The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine." [RESID:AA0043] +synonym: "peptidyl-cysteine N-acetylation" EXACT [] +xref: RESID:AA0043 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018533 ! peptidyl-cysteine acetylation + +[Term] +id: GO:0018276 +name: isopeptide cross-linking via N6-glycyl-L-lysine +namespace: biological_process +def: "The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination." [RESID:AA0125] +comment: See also the biological process term 'peptide cross-linking via S-glycyl-L-cysteine ; GO:0018255'. +xref: RESID:AA0125 +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018262 ! isopeptide cross-linking +relationship: part_of GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0018277 +name: protein deamination +namespace: biological_process +def: "The removal of an amino group from a protein amino acid." [GOC:ai] +synonym: "protein amino acid deamination" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018278 +name: N-terminal peptidyl-threonine deamination +namespace: biological_process +def: "The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid." [RESID:AA0129] +xref: RESID:AA0129 +is_a: GO:0018058 ! N-terminal protein amino acid deamination, from amino carbon +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018279 +name: protein N-linked glycosylation via asparagine +namespace: biological_process +def: "The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification." [GOC:jsg, RESID:AA0151, RESID:AA0420, RESID:AA0421] +synonym: "protein amino acid N-linked glycosylation via asparagine" EXACT [GOC:bf] +is_a: GO:0006487 ! protein N-linked glycosylation +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018280 +name: protein S-linked glycosylation +namespace: biological_process +def: "A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine." [GOC:ai, GOC:jsg, GOC:pr] +synonym: "protein amino acid S-linked glycosylation" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0018281 +name: GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine +namespace: biological_process +def: "The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0166] +synonym: "GSI anchor anabolism via N-seryl-glycosylsphingolipidinositolethanolamine" EXACT [] +synonym: "GSI anchor formation via N-seryl-glycosylsphingolipidinositolethanolamine" EXACT [] +synonym: "GSI anchor synthesis via N-seryl-glycosylsphingolipidinositolethanolamine" EXACT [] +xref: RESID:AA0166 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0042082 ! GSI anchor biosynthetic process + +[Term] +id: GO:0018282 +name: metal incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide." [GOC:jsg] +synonym: "metal incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0006464 ! cellular protein modification process +relationship: part_of GO:0031163 ! metallo-sulfur cluster assembly + +[Term] +id: GO:0018283 +name: iron incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of iron into a metallo-sulfur cluster." [GOC:ai] +synonym: "iron incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0016226 ! iron-sulfur cluster assembly +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018284 +name: iron incorporation into protein via tetrakis-L-cysteinyl iron +namespace: biological_process +def: "The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein)." [RESID:AA0136] +xref: RESID:AA0136 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018285 +name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide +namespace: biological_process +def: "The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide." [RESID:AA0137] +synonym: "iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl diiron disulphide" EXACT [] +xref: RESID:AA0137 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018286 +name: obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide +namespace: biological_process +def: "OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form." [RESID:AA0138] +comment: This term was made obsolete because the three-iron three-sulfur cluster is now thought not to exist except possibly as an intermediate form. +synonym: "iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide" EXACT [] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron trisulphide" EXACT [] +is_obsolete: true +consider: GO:0018198 +consider: GO:0018283 + +[Term] +id: GO:0018287 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide." [RESID:AA0139] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron tetrasulphide" EXACT [] +xref: RESID:AA0139 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018288 +name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide." [RESID:AA0140] +synonym: "iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0140 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018289 +name: molybdenum incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of molybdenum into a metallo-sulfur cluster." [GOC:ai] +synonym: "molybdenum incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018290 +name: iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide +namespace: biological_process +def: "The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase." [RESID:AA0141] +synonym: "iron and molybdenum incorporation into iron-molybdenum-sulphur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulphide" EXACT [] +xref: RESID:AA0141 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster +is_a: GO:0018291 ! molybdenum incorporation into iron-sulfur cluster + +[Term] +id: GO:0018291 +name: molybdenum incorporation into iron-sulfur cluster +namespace: biological_process +def: "The incorporation of molybdenum into an iron-sulfur cluster." [GOC:ai] +synonym: "molybdenum incorporation into iron-sulphur cluster" EXACT [] +is_a: GO:0016226 ! iron-sulfur cluster assembly +is_a: GO:0018289 ! molybdenum incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018292 +name: molybdenum incorporation via L-cysteinyl molybdopterin +namespace: biological_process +def: "The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin." [RESID:AA0142] +xref: RESID:AA0142 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex + +[Term] +id: GO:0018293 +name: protein-FAD linkage +namespace: biological_process +def: "The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD)." [GOC:ai] +is_a: GO:0018065 ! protein-cofactor linkage + +[Term] +id: GO:0018294 +name: protein-FAD linkage via S-(8alpha-FAD)-L-cysteine +namespace: biological_process +def: "The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine." [RESID:AA0143] +xref: RESID:AA0143 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018293 ! protein-FAD linkage + +[Term] +id: GO:0018295 +name: protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine +namespace: biological_process +def: "The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine." [RESID:AA0144] +xref: RESID:AA0144 +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018293 ! protein-FAD linkage + +[Term] +id: GO:0018296 +name: protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine +namespace: biological_process +def: "The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine." [RESID:AA0145] +xref: RESID:AA0145 +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018293 ! protein-FAD linkage + +[Term] +id: GO:0018297 +name: protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine +namespace: biological_process +def: "The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine." [RESID:AA0221] +xref: RESID:AA0221 +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018293 ! protein-FAD linkage + +[Term] +id: GO:0018298 +name: protein-chromophore linkage +namespace: biological_process +def: "The covalent or noncovalent attachment of a chromophore to a protein." [GOC:ma] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018299 +name: iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide +namespace: biological_process +def: "The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide." [RESID:AA0225] +synonym: "iron incorporation into the Rieske iron-sulphur cluster via bis-L-cysteinyl bis-L-histidino diiron disulphide" EXACT [] +xref: RESID:AA0225 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018300 +name: obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide +namespace: biological_process +def: "OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide." [RESID:AA0226] +comment: This term was made obsolete because the prismane 6Fe-6S cluster is now thought not to exist. +synonym: "iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide" EXACT [] +synonym: "iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl hexairon hexasulphide" EXACT [] +is_obsolete: true +consider: GO:0018198 +consider: GO:0018283 + +[Term] +id: GO:0018301 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon +namespace: biological_process +def: "The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon." [RESID:AA0268] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-cysteine persulphido-bis-L-glutamato-L-histidino tetrairon" EXACT [] +xref: RESID:AA0268 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018302 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide." [RESID:AA0284] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0284 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018303 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide." [RESID:AA0285] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0285 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018304 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide." [RESID:AA0286] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0286 +is_a: GO:0018197 ! peptidyl-aspartic acid modification +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018305 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide." [RESID:AA0288] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0288 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018306 +name: iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide." [RESID:AA0289] +synonym: "iron incorporation into iron-sulphur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulphide" EXACT [] +xref: RESID:AA0289 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018307 +name: enzyme active site formation +namespace: biological_process +def: "The modification of part of an enzyme to form the active site." [GOC:ai] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018308 +name: obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine +namespace: biological_process +def: "OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase." [PMID:1463470, RESID:AA0287] +comment: This term was made obsolete because this process does not occur: the modification occurs before it can be an active site. +synonym: "enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine" EXACT [] +is_obsolete: true + +[Term] +id: GO:0018309 +name: protein-FMN linkage +namespace: biological_process +def: "The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN)." [GOC:mah] +is_a: GO:0018065 ! protein-cofactor linkage + +[Term] +id: GO:0018310 +name: protein-FMN linkage via S-(6-FMN)-L-cysteine +namespace: biological_process +def: "The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine." [RESID:AA0220] +xref: RESID:AA0220 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0018311 +name: peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine." [RESID:AA0236] +synonym: "peptidyl-N4-hydroxymethyl-L-asparagine anabolism from peptidyl-asparagine" EXACT [] +synonym: "peptidyl-N4-hydroxymethyl-L-asparagine formation from peptidyl-asparagine" EXACT [] +synonym: "peptidyl-N4-hydroxymethyl-L-asparagine synthesis from peptidyl-asparagine" EXACT [] +xref: RESID:AA0236 +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0018312 +name: peptidyl-serine ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine." [RESID:AA0237] +xref: RESID:AA0237 +is_a: GO:0006471 ! protein ADP-ribosylation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018313 +name: peptide cross-linking via L-alanyl-5-imidazolinone glycine +namespace: biological_process +def: "The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water." [RESID:AA0187] +xref: RESID:AA0187 +is_a: GO:0018194 ! peptidyl-alanine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine + +[Term] +id: GO:0018314 +name: obsolete protein-pyrroloquinoline-quinone linkage +namespace: biological_process +def: "OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine." [PMID:7665488, RESID:AA0283] +synonym: "protein-pyrroloquinoline-quinone linkage" EXACT [] +is_obsolete: true +replaced_by: GO:0006464 + +[Term] +id: GO:0018315 +name: molybdenum incorporation into molybdenum-molybdopterin complex +namespace: biological_process +alt_id: GO:0042041 +def: "The incorporation of molybdenum into a molybdenum-molybdopterin complex." [GOC:ai] +synonym: "molybdenum incorporation into metallo-pterin complex" EXACT [] +is_a: GO:0042040 ! metal incorporation into metallo-molybdopterin complex +relationship: has_part GO:0061599 ! molybdopterin molybdotransferase activity + +[Term] +id: GO:0018316 +name: peptide cross-linking via L-cystine +namespace: biological_process +def: "The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain." [RESID:AA0025] +xref: RESID:AA0025 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018317 +name: protein C-linked glycosylation via tryptophan +namespace: biological_process +def: "The glycosylation of a carbon atom of a peptidyl-tryptophan residue." [GOC:ai] +synonym: "protein amino acid C-linked glycosylation via tryptophan" EXACT [GOC:bf] +is_a: GO:0018103 ! protein C-linked glycosylation +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0018320 +name: enzyme active site formation via S-methyl-L-cysteine +namespace: biological_process +def: "The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine." [RESID:AA0234] +xref: RESID:AA0234 +is_a: GO:0018125 ! peptidyl-cysteine methylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018321 +name: protein glucuronylation +namespace: biological_process +def: "The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose." [GOC:ai, GOC:pr] +synonym: "protein amino acid glucuronylation" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0018322 +name: protein tyrosinylation +namespace: biological_process +def: "The addition of a tyrosine molecule to a protein amino acid." [GOC:ai] +synonym: "protein amino acid tyrosinylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018323 +name: enzyme active site formation via L-cysteine sulfinic acid +namespace: biological_process +def: "The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid." [RESID:AA0262] +synonym: "enzyme active site formation via L-cysteine sulphinic acid" EXACT [] +xref: RESID:AA0262 +is_a: GO:0018171 ! peptidyl-cysteine oxidation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018324 +name: enzyme active site formation via L-cysteine sulfenic acid +namespace: biological_process +def: "The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase." [PMID:2501303, RESID:AA0205] +synonym: "enzyme active site formation via L-cysteine sulphenic acid" EXACT [] +xref: RESID:AA0205 +is_a: GO:0018171 ! peptidyl-cysteine oxidation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018325 +name: enzyme active site formation via S-phospho-L-cysteine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine." [RESID:AA0034] +xref: RESID:AA0034 +is_a: GO:0018218 ! peptidyl-cysteine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018326 +name: enzyme active site formation via S-acetyl-L-cysteine +namespace: biological_process +def: "The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine." [RESID:AA0056] +xref: RESID:AA0056 +is_a: GO:0018219 ! peptidyl-cysteine S-acetylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018327 +name: enzyme active site formation via 1'-phospho-L-histidine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine)." [RESID:AA0035] +xref: RESID:AA0035 +is_a: GO:0018106 ! peptidyl-histidine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018328 +name: enzyme active site formation via 3'-phospho-L-histidine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)." [RESID:AA0036] +xref: RESID:AA0036 +is_a: GO:0018106 ! peptidyl-histidine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018329 +name: enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine +namespace: biological_process +def: "The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase." [RESID:AA0227] +xref: RESID:AA0227 +is_a: GO:0018116 ! peptidyl-lysine adenylylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018330 +name: enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine +namespace: biological_process +def: "The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme." [RESID:AA0228] +xref: RESID:AA0228 +is_a: GO:0018261 ! peptidyl-lysine guanylylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018331 +name: enzyme active site formation via O-phospho-L-serine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine." [RESID:AA0037] +xref: RESID:AA0037 +is_a: GO:0018105 ! peptidyl-serine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018332 +name: enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine +namespace: biological_process +def: "The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I." [RESID:AA0267] +xref: RESID:AA0267 +is_a: GO:0018178 ! peptidyl-threonine adenylylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018333 +name: enzyme active site formation via O-phospho-L-threonine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine." [RESID:AA0038] +xref: RESID:AA0038 +is_a: GO:0018107 ! peptidyl-threonine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018334 +name: enzyme active site formation via O4'-phospho-L-tyrosine +namespace: biological_process +def: "The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine." [RESID:AA0039] +xref: RESID:AA0039 +is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018335 +name: protein succinylation +namespace: biological_process +def: "The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue." [GOC:bf] +synonym: "protein amino acid succinylation" EXACT [GOC:bf] +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0018336 +name: peptidyl-tyrosine hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine." [GOC:ai] +is_a: GO:0018126 ! protein hydroxylation + +[Term] +id: GO:0018337 +name: obsolete enzyme active site formation via L-2',4',5'-topaquinone +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because this process does not occur: the modification occurs before it can be an active site. +synonym: "enzyme active site formation via L-2',4',5'-topaquinone" EXACT [] +is_obsolete: true + +[Term] +id: GO:0018338 +name: obsolete protein amino acid cinnamylation +namespace: biological_process +def: "OBSOLETE. The modification of a protein amino acid by cinnamylation." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "protein amino acid cinnamylation" EXACT [] +is_obsolete: true +consider: GO:0018097 + +[Term] +id: GO:0018339 +name: peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid +namespace: biological_process +def: "The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12." [RESID:AA0232] +synonym: "peptidyl-aspartic acid methylthiolation" EXACT [] +synonym: "peptidyl-L-beta-methylthioaspartic acid anabolism from peptidyl-aspartic acid" EXACT [] +synonym: "peptidyl-L-beta-methylthioaspartic acid formation from peptidyl-aspartic acid" EXACT [] +synonym: "peptidyl-L-beta-methylthioaspartic acid synthesis from peptidyl-aspartic acid" EXACT [] +xref: RESID:AA0232 +is_a: GO:0018197 ! peptidyl-aspartic acid modification +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018340 +name: peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine +namespace: biological_process +def: "The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine." [RESID:AA0264] +synonym: "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine anabolism from peptidyl-serine" EXACT [] +synonym: "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine formation from peptidyl-serine" EXACT [] +synonym: "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine synthesis from peptidyl-serine" EXACT [] +xref: RESID:AA0264 +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018341 +name: peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine +namespace: biological_process +def: "The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine." [PSI-MOD:00292] +synonym: "peptidyl-N6-pyruvic acid 2-iminyl-L-lysine anabolism" EXACT [] +synonym: "peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthesis" EXACT [] +synonym: "peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthetic process" EXACT [] +synonym: "peptidyl-N6-pyruvic acid 2-iminyl-L-lysine formation" EXACT [] +synonym: "peptidyl-N6-pyruvic acid 2-iminyl-L-lysine synthesis" EXACT [] +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018342 +name: protein prenylation +namespace: biological_process +alt_id: GO:0018346 +def: "The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added." [GOC:di, ISBN:0198506732] +synonym: "C-terminal protein prenylation" NARROW [] +synonym: "protein amino acid prenylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0097354 ! prenylation + +[Term] +id: GO:0018343 +name: protein farnesylation +namespace: biological_process +alt_id: GO:0018347 +def: "The covalent attachment of a farnesyl group to a protein." [GOC:jl] +synonym: "C-terminal protein farnesylation" NARROW [] +synonym: "protein amino acid farnesylation" EXACT [GOC:bf] +is_a: GO:0018342 ! protein prenylation + +[Term] +id: GO:0018344 +name: protein geranylgeranylation +namespace: biological_process +alt_id: GO:0018348 +def: "The covalent attachment of a geranylgeranyl group to a protein." [GOC:jl] +synonym: "C-terminal protein geranylgeranylation" NARROW [] +synonym: "protein amino acid geranylgeranylation" EXACT [GOC:bf] +is_a: GO:0018342 ! protein prenylation + +[Term] +id: GO:0018345 +name: protein palmitoylation +namespace: biological_process +alt_id: GO:0018318 +alt_id: GO:0018349 +def: "The covalent attachment of a palmitoyl group to a protein." [GOC:jl, PMID:15520806] +synonym: "protein amino acid palmitoylation" EXACT [GOC:bf] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0018350 +name: protein esterification +namespace: biological_process +def: "The addition of an ester group to a protein amino acid." [GOC:ai] +synonym: "protein amino acid esterification" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018351 +name: peptidyl-cysteine esterification +namespace: biological_process +def: "The addition of an ester group to a cysteine residue in a protein." [GOC:mah] +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0018352 +name: protein-pyridoxal-5-phosphate linkage +namespace: biological_process +def: "The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate." [GOC:mah] +is_a: GO:0018065 ! protein-cofactor linkage + +[Term] +id: GO:0018353 +name: protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine +namespace: biological_process +alt_id: GO:0018380 +def: "The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine." [RESID:AA0131] +xref: RESID:AA0131 +is_a: GO:0017009 ! protein-phycocyanobilin linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018355 +name: protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine +namespace: biological_process +def: "The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine." [RESID:AA00167] +is_a: GO:0018247 ! protein-phosphoribosyl dephospho-coenzyme A linkage + +[Term] +id: GO:0018356 +name: protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine +namespace: biological_process +alt_id: GO:0018382 +def: "The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine." [RESID:AA0258] +xref: RESID:AA0258 +is_a: GO:0017008 ! protein-phycobiliviolin linkage + +[Term] +id: GO:0018357 +name: protein-phycourobilin linkage via phycourobilin-bis-L-cysteine +namespace: biological_process +alt_id: GO:0018383 +def: "The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine." [RESID:AA0260] +xref: RESID:AA0260 +is_a: GO:0017010 ! protein-phycourobilin linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018358 +name: protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine +namespace: biological_process +alt_id: GO:0018381 +def: "The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine." [RESID:AA0133] +xref: RESID:AA0133 +is_a: GO:0017012 ! protein-phytochromobilin linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018359 +name: protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine +namespace: biological_process +alt_id: GO:0018385 +def: "The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine." [RESID:AA0266] +synonym: "protein-haem P460 linkage via haem P460-bis-L-cysteine-L-tyrosine" EXACT [] +xref: RESID:AA0266 +is_a: GO:0018174 ! protein-heme P460 linkage +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0018360 +name: protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine +namespace: biological_process +alt_id: GO:0018384 +def: "The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine." [RESID:AA0271] +synonym: "protein-haem P460 linkage via haem P460-bis-L-cysteine-L-lysine" EXACT [] +xref: RESID:AA0271 +is_a: GO:0018174 ! protein-heme P460 linkage +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018361 +name: peptidyl-glutamine 2-methylation +namespace: biological_process +def: "The methylation of glutamine to form 2-methyl-L-glutamine." [http://www.uni-marburg.de/mpi/thauer/thauer_res.html, RESID:AA0273] +xref: RESID:AA0273 +is_a: GO:0018364 ! peptidyl-glutamine methylation + +[Term] +id: GO:0018362 +name: peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester +namespace: biological_process +alt_id: GO:0019924 +def: "The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester." [RESID:AA0279] +synonym: "peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester" EXACT [] +xref: RESID:AA0279 +is_a: GO:0018186 ! peroxidase-heme linkage +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018363 +name: peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium +namespace: biological_process +alt_id: GO:0019925 +def: "The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium." [RESID:AA0280] +synonym: "peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium" EXACT [] +synonym: "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulphonium" EXACT [] +xref: RESID:AA0280 +is_a: GO:0018186 ! peroxidase-heme linkage +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018206 ! peptidyl-methionine modification + +[Term] +id: GO:0018364 +name: peptidyl-glutamine methylation +namespace: biological_process +def: "The addition of a methyl group to a glutamine residue in a protein." [GOC:mah] +is_a: GO:0006479 ! protein methylation + +[Term] +id: GO:0018365 +name: protein-serine epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine." [EC:5.1.1.16] +synonym: "protein-serine racemase activity" EXACT [EC:5.1.1.16] +xref: EC:5.1.1.16 +xref: MetaCyc:5.1.1.16-RXN +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives + +[Term] +id: GO:0018366 +name: chiral amino acid racemization +namespace: biological_process +def: "The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid." [GOC:jsg, ISBN:0198506732] +is_a: GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0018367 +name: obsolete free L-amino acid racemization +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it is not clear that this process occurs. +synonym: "free L-amino acid racemization" EXACT [] +is_obsolete: true +consider: GO:0006520 + +[Term] +id: GO:0018376 +name: peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine +namespace: biological_process +def: "The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16)." [RESID:AA0026] +comment: See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'. +xref: RESID:AA0026 +is_a: GO:0042265 ! peptidyl-asparagine hydroxylation + +[Term] +id: GO:0018377 +name: protein myristoylation +namespace: biological_process +alt_id: GO:0018319 +def: "The covalent attachment of a myristoyl group to a protein." [GOC:ai] +synonym: "protein amino acid myristoylation" EXACT [GOC:bf] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0018378 +name: cytochrome c-heme linkage via heme-L-cysteine +namespace: biological_process +def: "The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine." [RESID:AA0135] +synonym: "cytochrome c-haem linkage via haem-L-cysteine" EXACT [] +xref: RESID:AA0135 +is_a: GO:0018063 ! cytochrome c-heme linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018379 +name: cytochrome c-heme linkage via heme-bis-L-cysteine +namespace: biological_process +def: "The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine." [RESID:AA0134] +synonym: "cytochrome c-haem linkage via haem-bis-L-cysteine" EXACT [] +xref: RESID:AA0134 +is_a: GO:0018063 ! cytochrome c-heme linkage +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018386 +name: N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine +namespace: biological_process +def: "The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine." [RESID:AA0274] +xref: RESID:AA0274 +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0018387 +name: N-terminal peptidyl-amino acid deamination to pyruvic acid +namespace: biological_process +def: "The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue." [RESID:AA0127] +xref: RESID:AA0127 +is_a: GO:0018058 ! N-terminal protein amino acid deamination, from amino carbon + +[Term] +id: GO:0018388 +name: N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine +namespace: biological_process +def: "The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine." [RESID:AA0275] +xref: RESID:AA0275 +is_a: GO:0018213 ! peptidyl-valine modification +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0018389 +name: N-terminal peptidyl-valine deamination +namespace: biological_process +def: "The deamination of the N-terminal valine residue of a protein to form isobutyrate." [GOC:ma, GOC:mah] +is_a: GO:0018058 ! N-terminal protein amino acid deamination, from amino carbon + +[Term] +id: GO:0018390 +name: peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine +namespace: biological_process +def: "The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester." [RESID:AA0072] +synonym: "peptidyl-L-glutamic acid 5-methyl ester anabolism from peptidyl-glutamic acid or peptidyl-glutamine" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester formation from peptidyl-glutamic acid or peptidyl-glutamine" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester synthesis from peptidyl-glutamic acid or peptidyl-glutamine" EXACT [] +xref: RESID:AA0072 +is_a: GO:0018199 ! peptidyl-glutamine modification +is_a: GO:0018442 ! peptidyl-glutamic acid esterification + +[Term] +id: GO:0018391 +name: C-terminal peptidyl-glutamic acid tyrosinylation +namespace: biological_process +def: "The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein." [GOC:mah] +is_a: GO:0018166 ! C-terminal protein-tyrosinylation +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018392 +name: glycoprotein 3-alpha-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+)." [EC:2.4.1.214, RHEA:24444] +synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity" EXACT [] +synonym: "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity" EXACT [EC:2.4.1.214] +synonym: "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity" EXACT [EC:2.4.1.214] +xref: EC:2.4.1.214 +xref: KEGG_REACTION:R06015 +xref: MetaCyc:2.4.1.214-RXN +xref: RHEA:24444 +is_a: GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0018393 +name: internal peptidyl-lysine acetylation +namespace: biological_process +def: "The addition of an acetyl group to a non-terminal lysine residue in a protein." [GOC:mah] +is_a: GO:0006475 ! internal protein amino acid acetylation +is_a: GO:0018394 ! peptidyl-lysine acetylation + +[Term] +id: GO:0018394 +name: peptidyl-lysine acetylation +namespace: biological_process +def: "The acetylation of peptidyl-lysine." [GOC:mah] +is_a: GO:0006473 ! protein acetylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018395 +name: peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine +namespace: biological_process +def: "The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine." [RESID:AA0028] +xref: RESID:AA0028 +is_a: GO:0017185 ! peptidyl-lysine hydroxylation + +[Term] +id: GO:0018396 +name: peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine +namespace: biological_process +def: "The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine." [RESID:AA0235] +xref: RESID:AA0235 +is_a: GO:0017185 ! peptidyl-lysine hydroxylation + +[Term] +id: GO:0018397 +name: peptidyl-phenylalanine bromination to L-2'-bromophenylalanine +namespace: biological_process +def: "The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine." [RESID:AA0174] +xref: RESID:AA0174 +is_a: GO:0018075 ! peptidyl-phenylalanine bromination + +[Term] +id: GO:0018398 +name: peptidyl-phenylalanine bromination to L-3'-bromophenylalanine +namespace: biological_process +def: "The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine." [RESID:AA0175] +xref: RESID:AA0175 +is_a: GO:0018075 ! peptidyl-phenylalanine bromination + +[Term] +id: GO:0018399 +name: peptidyl-phenylalanine bromination to L-4'-bromophenylalanine +namespace: biological_process +def: "The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine." [RESID:AA0176] +xref: RESID:AA0176 +is_a: GO:0018075 ! peptidyl-phenylalanine bromination + +[Term] +id: GO:0018400 +name: peptidyl-proline hydroxylation to 3-hydroxy-L-proline +namespace: biological_process +def: "The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase." [RESID:AA0029] +comment: See also the molecular function term 'procollagen-proline 3-dioxygenase activity ; GO:0019797'. +xref: RESID:AA0029 +is_a: GO:0019511 ! peptidyl-proline hydroxylation + +[Term] +id: GO:0018401 +name: peptidyl-proline hydroxylation to 4-hydroxy-L-proline +namespace: biological_process +def: "The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase." [RESID:AA0030] +comment: See also the molecular function term 'procollagen-proline 4-dioxygenase activity ; GO:0004656'. +xref: RESID:AA0030 +is_a: GO:0019511 ! peptidyl-proline hydroxylation + +[Term] +id: GO:0018402 +name: protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine +namespace: biological_process +def: "Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues." [RESID:AA0208] +synonym: "protein-chondroitin sulphate linkage via chondroitin sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT [] +xref: RESID:AA0208 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0030204 ! chondroitin sulfate metabolic process + +[Term] +id: GO:0018403 +name: protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine +namespace: biological_process +def: "Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues." [PMID:7338506, RESID:AA0209] +synonym: "protein-dermatan sulphate linkage via dermatan 4-sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT [] +xref: RESID:AA0209 +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018404 +name: protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine +namespace: biological_process +def: "Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues." [RESID:AA0210] +synonym: "protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT [] +xref: RESID:AA0210 +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0018405 +name: protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine +namespace: biological_process +def: "Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues." [RESID:AA0247] +synonym: "protein-keratan sulphate linkage via keratan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine" EXACT [] +xref: RESID:AA0247 +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0018406 +name: protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan +namespace: biological_process +alt_id: GO:0032004 +def: "The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring." [PMID:7947762, PMID:9450955, RESID:AA0217] +synonym: "protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan" EXACT [GOC:bf] +synonym: "protein amino acid C-linked mannosylation" EXACT [] +xref: RESID:AA0217 +is_a: GO:0018317 ! protein C-linked glycosylation via tryptophan +is_a: GO:0035268 ! protein mannosylation + +[Term] +id: GO:0018407 +name: peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine +namespace: biological_process +def: "The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine)." [RESID:AA0177] +synonym: "peptidyl-thyronine iodination to form triiodothyronine" BROAD [] +xref: RESID:AA0177 +is_a: GO:0018078 ! peptidyl-thyronine iodination + +[Term] +id: GO:0018408 +name: peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine +namespace: biological_process +def: "The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine)." [RESID:AA0178] +xref: RESID:AA0178 +is_a: GO:0018078 ! peptidyl-thyronine iodination + +[Term] +id: GO:0018410 +name: C-terminal protein amino acid modification +namespace: biological_process +def: "The alteration of the C-terminal amino acid residue in a protein." [GOC:mah] +synonym: "peptide or protein carboxyl-terminal blocking" RELATED [] +synonym: "peptide/protein carboxyl-terminal blocking" RELATED [] +is_a: GO:0043687 ! post-translational protein modification + +[Term] +id: GO:0018411 +name: protein glucuronidation +namespace: biological_process +def: "The modification of a protein by amino acid glucuronidation." [GOC:ai] +synonym: "protein amino acid glucuronidation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0018412 +name: protein O-glucuronidation +namespace: biological_process +def: "The modification of a protein by glucuronidation on an amino acid oxygen atom." [GOC:mah] +synonym: "protein amino acid O-glucuronidation" EXACT [GOC:bf] +is_a: GO:0018411 ! protein glucuronidation + +[Term] +id: GO:0018413 +name: peptidyl-serine O-glucuronidation +namespace: biological_process +def: "The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine." [RESID:AA0291] +xref: RESID:AA0291 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018412 ! protein O-glucuronidation + +[Term] +id: GO:0018414 +name: nickel incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of nickel into a metallo-sulfur cluster." [GOC:ai] +synonym: "nickel incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018415 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide +namespace: biological_process +def: "The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide." [RESID:AA0292] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide" EXACT [] +xref: RESID:AA0292 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018416 +name: nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide +namespace: biological_process +def: "The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide." [RESID:AA0292] +synonym: "nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide" EXACT [] +xref: RESID:AA0292 +is_a: GO:0016226 ! iron-sulfur cluster assembly +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018414 ! nickel incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018417 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide +namespace: biological_process +def: "The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide." [RESID:AA0293] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide" EXACT [] +xref: RESID:AA0293 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018418 +name: nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide +namespace: biological_process +def: "The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide." [RESID:AA0293] +synonym: "nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide" EXACT [] +xref: RESID:AA0 +is_a: GO:0016226 ! iron-sulfur cluster assembly +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018414 ! nickel incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018419 +name: protein catenane formation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain." [ISBN:0198506732] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0018420 +name: peptide cross-linking via N6-(L-isoaspartyl)-L-lysine +namespace: biological_process +def: "The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues." [RESID:AA0294] +xref: RESID:AA0294 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018196 ! peptidyl-asparagine modification +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0018421 +name: UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein." [GOC:mah, PMID:9353330] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0018422 +name: GDP-mannose:serine-protein mannose-1-phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein." [GOC:mah, PMID:10037765] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0018423 +name: protein C-terminal leucine carboxyl O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein." [PMID:8514774] +synonym: "protein phosphatase methyltransferase activity" NARROW [] +synonym: "protein-leucine O-methyltransferase activity" EXACT [] +xref: Reactome:R-HSA-8856945 "PP2A methylation by LCMT1" +is_a: GO:0003880 ! protein C-terminal carboxyl O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0018424 +name: peptidyl-glutamic acid poly-ADP-ribosylation +namespace: biological_process +def: "This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way." [RESID:AA0295] +xref: RESID:AA0295 +is_a: GO:0006471 ! protein ADP-ribosylation +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0018425 +name: O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds." [RESID:AA0296] +synonym: "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine anabolism" EXACT [] +synonym: "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthesis" EXACT [] +synonym: "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine formation" EXACT [] +synonym: "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine synthesis" EXACT [] +xref: RESID:AA0296 +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0042077 ! protein phosphate-linked glycosylation via serine +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0046349 ! amino sugar biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0018426 +name: O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage." [RESID:AA0297] +synonym: "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine anabolism" EXACT [] +synonym: "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthesis" EXACT [] +synonym: "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine formation" EXACT [] +synonym: "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine synthesis" EXACT [] +xref: RESID:AA0297 +is_a: GO:0042077 ! protein phosphate-linked glycosylation via serine + +[Term] +id: GO:0018427 +name: copper incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of copper into a metallo-sulfur cluster." [GOC:ai] +synonym: "copper incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018428 +name: copper incorporation into copper-sulfur cluster +namespace: biological_process +def: "The incorporation of copper into a copper-sulfur cluster." [GOC:ai] +synonym: "copper incorporation into copper-sulphur cluster" EXACT [] +is_a: GO:0018427 ! copper incorporation into metallo-sulfur cluster + +[Term] +id: GO:0018429 +name: copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide +namespace: biological_process +def: "The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide." [RESID:AA0298] +synonym: "copper incorporation into copper-sulphur cluster via heptakis-L-histidino tetracopper mu4-sulphide hydroxide" EXACT [] +xref: RESID:AA0298 +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018428 ! copper incorporation into copper-sulfur cluster + +[Term] +id: GO:0018439 +name: peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine +namespace: biological_process +alt_id: GO:0018440 +def: "The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester." [RESID:AA0299] +synonym: "peptidyl-leucine esterification" EXACT [] +xref: RESID:AA0299 +is_a: GO:0006481 ! C-terminal protein methylation +is_a: GO:0018203 ! peptidyl-isoleucine modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0018441 +name: iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide +namespace: biological_process +def: "The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase." [PMID:9063865, RESID:AA0300] +synonym: "iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulphide" EXACT [] +xref: RESID:AA0300 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster +is_a: GO:0018418 ! nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide + +[Term] +id: GO:0018442 +name: peptidyl-glutamic acid esterification +namespace: biological_process +def: "The addition of an ester group to a glutamic acid residue in a protein." [GOC:mah] +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0018443 +name: enzyme active site formation via L-aspartic 4-phosphoric anhydride +namespace: biological_process +def: "The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride." [RESID:AA0033] +xref: RESID:AA0033 +is_a: GO:0018217 ! peptidyl-aspartic acid phosphorylation +is_a: GO:0018307 ! enzyme active site formation + +[Term] +id: GO:0018444 +name: translation release factor complex +namespace: cellular_component +def: "A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome." [ISBN:0198547684] +synonym: "eukaryotic peptide chain release factor" EXACT [] +synonym: "peptide chain release factor" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0018445 +name: prothoracicotrophic hormone activity +namespace: molecular_function +def: "The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects." [GOC:mah, PMID:3301403] +is_a: GO:0005184 ! neuropeptide hormone activity + +[Term] +id: GO:0018446 +name: pinocarveol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-." [UM-BBD_reactionID:r0717] +xref: UM-BBD_reactionID:r0717 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018447 +name: chloral hydrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol." [UM-BBD_enzymeID:e0229] +xref: UM-BBD_enzymeID:e0229 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018448 +name: hydroxymethylmethylsilanediol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O." [UM-BBD_reactionID:r0638] +xref: UM-BBD_reactionID:r0638 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018449 +name: 1-phenylethanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2." [UM-BBD_reactionID:r0032] +xref: UM-BBD_reactionID:r0032 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018450 +name: myrtenol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal." [UM-BBD_reactionID:r0710] +xref: UM-BBD_reactionID:r0710 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018451 +name: epoxide dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA." [UM-BBD_reactionID:r0595] +xref: UM-BBD_reactionID:r0595 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018452 +name: 5-exo-hydroxycamphor dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane." [UM-BBD_reactionID:r0427] +xref: EC:1.1.1.327 +xref: MetaCyc:R542-RXN +xref: UM-BBD_reactionID:r0427 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018453 +name: 2-hydroxytetrahydrofuran dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone." [UM-BBD_reactionID:r0018] +xref: UM-BBD_reactionID:r0018 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018454 +name: acetoacetyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+." [EC:1.1.1.36] +synonym: "(R)-3-hydroxyacyl-CoA dehydrogenase activity" EXACT [EC:1.1.1.36] +synonym: "(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.36] +synonym: "acetoacetyl coenzyme A reductase activity" EXACT [EC:1.1.1.36] +synonym: "beta-ketoacyl-CoA reductase" BROAD [EC:1.1.1.36] +synonym: "D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity" EXACT [EC:1.1.1.36] +synonym: "D-3-hydroxyacyl-CoA reductase activity" EXACT [EC:1.1.1.36] +synonym: "hydroxyacyl coenzyme-A dehydrogenase activity" EXACT [EC:1.1.1.36] +synonym: "NADP-linked acetoacetyl CoA reductase activity" EXACT [EC:1.1.1.36] +synonym: "NADPH:acetoacetyl-CoA reductase activity" EXACT [EC:1.1.1.36] +synonym: "short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity" EXACT [EC:1.1.1.36] +xref: EC:1.1.1.36 +xref: MetaCyc:RXN-7698 +xref: RHEA:22256 +xref: UM-BBD_reactionID:r0202 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018455 +name: alcohol dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+." [EC:1.1.1.71] +synonym: "alcohol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.71] +synonym: "aldehyde reductase (NADPH/NADH)" EXACT [EC:1.1.1.71] +xref: EC:1.1.1.71 +xref: MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN +xref: RHEA:10736 +xref: UM-BBD_reactionID:r0172 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018456 +name: aryl-alcohol dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+." [EC:1.1.1.90] +synonym: "aryl-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.90] +synonym: "benzyl alcohol dehydrogenase activity" NARROW [] +synonym: "p-hydroxybenzyl alcohol dehydrogenase activity" NARROW [EC:1.1.1.90] +xref: EC:1.1.1.90 +xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN +xref: UM-BBD_enzymeID:e0019 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018457 +name: perillyl-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde." [EC:1.1.1.144, RHEA:10664] +synonym: "perillyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.144] +synonym: "perillyl-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.144] +xref: EC:1.1.1.144 +xref: KEGG_REACTION:R03945 +xref: MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN +xref: RHEA:10664 +xref: UM-BBD_reactionID:r0729 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018458 +name: isopiperitenol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH." [EC:1.1.1.223, RHEA:20860] +synonym: "(-)-trans-isopiperitenol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.223] +xref: EC:1.1.1.223 +xref: KEGG_REACTION:R03261 +xref: MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN +xref: RHEA:20860 +xref: UM-BBD_reactionID:r0740 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018459 +name: carveol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH." [EC:1.1.1.243, RHEA:13629] +synonym: "(-)-trans-carveol dehydrogenase activity" EXACT [EC:1.1.1.243] +synonym: "(-)-trans-carveol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.243] +xref: EC:1.1.1.243 +xref: KEGG_REACTION:R03114 +xref: MetaCyc:CARVEOL-DEHYDROGENASE-RXN +xref: RHEA:13629 +xref: UM-BBD_reactionID:r0714 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018460 +name: cyclohexanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+." [EC:1.1.1.245] +synonym: "cyclohexanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.245] +xref: EC:1.1.1.245 +xref: MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN +xref: RHEA:10044 +xref: UM-BBD_reactionID:r0165 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018461 +name: fluoren-9-ol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+." [EC:1.1.1.256] +synonym: "9-fluorenol dehydrogenase activity" EXACT [] +synonym: "fluoren-9-ol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.256] +xref: EC:1.1.1.256 +xref: MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN +xref: UM-BBD_reactionID:r0408 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018462 +name: 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH." [EC:1.1.1.257, RHEA:24412] +synonym: "4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.257] +synonym: "4-(hydroxymethyl)benzenesulphonate dehydrogenase activity" EXACT [] +synonym: "4-sulfobenzyl alcohol dehydrogenase activity" EXACT [] +xref: EC:1.1.1.257 +xref: KEGG_REACTION:R05271 +xref: MetaCyc:1.1.1.257-RXN +xref: RHEA:24412 +xref: UM-BBD_reactionID:r0291 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018463 +name: 6-hydroxyhexanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH." [EC:1.1.1.258, RHEA:14225] +synonym: "6-hydroxyhexanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.258] +xref: EC:1.1.1.258 +xref: KEGG_REACTION:R05283 +xref: MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN +xref: RHEA:14225 +xref: UM-BBD_reactionID:r0174 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018464 +name: 3-hydroxypimeloyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH." [EC:1.1.1.259, RHEA:11168] +synonym: "3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.259] +xref: EC:1.1.1.259 +xref: KEGG_REACTION:R05305 +xref: MetaCyc:1.1.1.259-RXN +xref: RHEA:11168 +xref: UM-BBD_reactionID:r0196 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018465 +name: vanillyl-alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin." [EC:1.1.3.38, RHEA:10036] +synonym: "4-hydroxy-2-methoxybenzyl alcohol oxidase activity" EXACT [EC:1.1.3.38] +synonym: "vanillyl alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.38] +xref: EC:1.1.3.38 +xref: KEGG_REACTION:R02877 +xref: MetaCyc:1.1.3.38-RXN +xref: RHEA:10036 +xref: UM-BBD_reactionID:r0651 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0018466 +name: limonene-1,2-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene." [UM-BBD_reactionID:r0735] +xref: EC:1.1.99 +xref: UM-BBD_reactionID:r0735 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018467 +name: formaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH." [EC:1.2.1.46, RHEA:16425] +synonym: "formaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.46] +synonym: "glutathione-independent formaldehyde dehydrogenase activity" EXACT [] +xref: EC:1.2.1.46 +xref: KEGG_REACTION:R00604 +xref: MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN +xref: RHEA:16425 +xref: UM-BBD_reactionID:r0240 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0018468 +name: alcohol dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor." [EC:1.1.99.8] +synonym: "alcohol:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.8] +synonym: "alcohol:acceptor oxidoreductase activity" EXACT [EC:1.1.99.8] +synonym: "MDH" RELATED [EC:1.1.99.8] +synonym: "PQQ-dependent alcohol dehydrogenase activity" EXACT [] +synonym: "primary alcohol dehydrogenase" BROAD [EC:1.1.99.8] +synonym: "quinohemoprotein alcohol dehydrogenase activity" EXACT [EC:1.1.99.8] +synonym: "quinoprotein alcohol dehydrogenase activity" EXACT [EC:1.1.99.8] +synonym: "quinoprotein ethanol dehydrogenase activity" EXACT [EC:1.1.99.8] +xref: EC:1.1.99.8 +xref: UM-BBD_enzymeID:e0004 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0018469 +name: myrtenal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid." [UM-BBD_reactionID:r0711] +xref: UM-BBD_reactionID:r0711 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0018470 +name: 4-hydroxybutaraldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate." [UM-BBD_reactionID:r0014] +xref: UM-BBD_reactionID:r0014 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0018471 +name: 4-chlorobenzaldehyde oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-." [UM-BBD_reactionID:r0447] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0447 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018472 +name: 1-hydroxy-2-naphthaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate." [UM-BBD_reactionID:r0485] +xref: UM-BBD_reactionID:r0485 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018473 +name: cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid." [UM-BBD_reactionID:r0744] +xref: UM-BBD_reactionID:r0744 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018474 +name: 2-carboxybenzaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate." [UM-BBD_reactionID:r0490] +xref: EC:1.2.1 +xref: UM-BBD_reactionID:r0490 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0018475 +name: trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid." [UM-BBD_reactionID:r0745] +xref: UM-BBD_reactionID:r0745 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018477 +name: benzaldehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+." [EC:1.2.1.7] +synonym: "benzaldehyde:NADP+ oxidoreductase" EXACT [EC:1.2.1.7] +synonym: "NADP-linked benzaldehyde dehydrogenase" EXACT [EC:1.2.1.7] +xref: EC:1.2.1.7 +xref: MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:21660 +xref: UM-BBD_enzymeID:e0079 +is_a: GO:0019115 ! benzaldehyde dehydrogenase [NAD(P)+] activity +is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity + +[Term] +id: GO:0018478 +name: malonate-semialdehyde dehydrogenase (acetylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+." [EC:1.2.1.18] +synonym: "3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)" EXACT [EC:1.2.1.18] +synonym: "malonic semialdehyde oxidative decarboxylase activity" EXACT [] +xref: EC:1.2.1.18 +xref: MetaCyc:1.2.1.18-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018479 +name: benzaldehyde dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+." [EC:1.2.1.28] +synonym: "benzaldehyde (NAD) dehydrogenase activity" EXACT [EC:1.2.1.28] +synonym: "benzaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.28] +xref: EC:1.2.1.28 +xref: MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN +xref: RHEA:11840 +xref: UM-BBD_reactionID:r0269 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity +is_a: GO:0019115 ! benzaldehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0018480 +name: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+." [EC:1.2.1.60] +synonym: "5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.60] +synonym: "carboxymethylhydroxymuconic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.60] +xref: EC:1.2.1.60 +xref: MetaCyc:CHMS-DEHYDROGENASE-RXN +xref: RHEA:15681 +xref: UM-BBD_reactionID:r0365 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018481 +name: 4-hydroxymuconic-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis,trans-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH." [EC:1.2.1.61, RHEA:22420] +synonym: "4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.61] +xref: EC:1.2.1.61 +xref: KEGG_REACTION:R05236 +xref: MetaCyc:1.2.1.61-RXN +xref: RHEA:22420 +xref: UM-BBD_reactionID:r0229 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018482 +name: 4-formylbenzenesulfonate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH." [EC:1.2.1.62, RHEA:18833] +synonym: "4-formylbenzenesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.62] +synonym: "4-formylbenzenesulphonate dehydrogenase activity" EXACT [] +synonym: "toluene-sulfonate aldehyde dehydrogenase activity" EXACT [] +xref: EC:1.2.1.62 +xref: KEGG_REACTION:R05272 +xref: MetaCyc:1.2.1.62-RXN +xref: RHEA:18833 +xref: UM-BBD_reactionID:r0292 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018483 +name: 6-oxohexanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+." [EC:1.2.1.63] +synonym: "6-oxohexanoate:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.63] +xref: EC:1.2.1.63 +xref: MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN +xref: RHEA:13397 +xref: UM-BBD_reactionID:r0175 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018484 +name: 4-hydroxybenzaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+." [EC:1.2.1.64] +synonym: "3-hydroxybenzaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.64] +synonym: "p-hydroxybenzaldehyde dehydrogenase activity" EXACT [EC:1.2.1.64] +xref: EC:1.2.1.64 +xref: MetaCyc:HYDROXYBENZALDEHYDE-OXIDATION-NAD-RXN +xref: RHEA:20305 +xref: UM-BBD_reactionID:r0273 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0018485 +name: salicylaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+." [EC:1.2.1.65] +synonym: "salicylaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.65] +xref: EC:1.2.1.65 +xref: MetaCyc:1.2.1.65-RXN +xref: RHEA:18537 +xref: UM-BBD_enzymeID:e0256 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0018486 +name: 2-butanone oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate." [UM-BBD_reactionID:r0169] +xref: UM-BBD_reactionID:r0169 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0018487 +name: vanillate O-demethylase (anaerobic) activity +namespace: molecular_function +def: "Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate." [UM-BBD_reactionID:r0758] +xref: UM-BBD_reactionID:r0758 +is_a: GO:0032451 ! demethylase activity + +[Term] +id: GO:0018488 +name: aryl-aldehyde oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide." [EC:1.2.3.9] +synonym: "aryl-aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.9] +xref: EC:1.2.3.9 +xref: MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN +xref: UM-BBD_reactionID:r0145 +is_a: GO:0004031 ! aldehyde oxidase activity + +[Term] +id: GO:0018489 +name: vanillate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+)." [EC:1.14.13.82, RHEA:13021] +comment: Note that this was EC:1.2.3.12. +synonym: "4-hydroxy-3-methoxybenzoate demethylase activity" EXACT [EC:1.14.13.82] +synonym: "vanillate demethylase (aerobic) activity" EXACT [] +synonym: "vanillate demethylase activity" EXACT [] +synonym: "vanillate:oxygen oxidoreductase (demethylating)" EXACT [EC:1.14.13.82] +xref: EC:1.14.13.82 +xref: KEGG_REACTION:R05274 +xref: MetaCyc:RXN-10891 +xref: MetaCyc:RXN-2 +xref: RHEA:13021 +xref: UM-BBD_reactionID:r0146 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +is_a: GO:0032451 ! demethylase activity + +[Term] +id: GO:0018490 +name: 4-hydroxyphenylpyruvate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2)." [EC:1.2.3.13, RHEA:17197] +synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)" BROAD [EC:1.2.3.13] +xref: EC:1.2.3.13 +xref: KEGG_REACTION:R00042 +xref: MetaCyc:1.2.3.13-RXN +xref: RHEA:17197 +xref: UM-BBD_reactionID:r0299 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0018491 +name: 2-oxobutyrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin." [GOC:curators] +synonym: "2-ketobutyrate synthase activity" EXACT [] +synonym: "2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)" EXACT [] +synonym: "2-oxobutyrate-ferredoxin oxidoreductase activity" EXACT [] +synonym: "alpha-ketobutyrate synthase activity" EXACT [] +synonym: "alpha-ketobutyrate-ferredoxin oxidoreductase activity" EXACT [] +xref: MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN +xref: UM-BBD_reactionID:r0358 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018492 +name: carbon-monoxide dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor." [EC:1.2.7.4] +synonym: "anaerobic carbon monoxide dehydrogenase activity" EXACT [EC:1.2.7.4] +synonym: "carbon monoxide dehydrogenase activity" BROAD [] +synonym: "carbon-monoxide:acceptor oxidoreductase activity" EXACT [EC:1.2.7.4] +xref: EC:1.2.7.4 +xref: MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN +xref: RHEA:21040 +xref: UM-BBD_enzymeID:e0415 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0018493 +name: formylmethanofuran dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran." [EC:1.2.7.12, RHEA:19841] +synonym: "formylmethanofuran:(acceptor) oxidoreductase activity" EXACT [EC:1.2.7.12] +synonym: "formylmethanofuran:acceptor oxidoreductase activity" EXACT [EC:1.2.7.12] +xref: EC:1.2.7.12 +xref: KEGG_REACTION:R03015 +xref: MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN +xref: RHEA:19841 +xref: UM-BBD_reactionID:r0345 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0018494 +name: carvone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone." [UM-BBD_reactionID:r0732] +xref: EC:1.3.99.25 +xref: MetaCyc:RXN-9403 +xref: MetaCyc:RXN-9419 +xref: UM-BBD_reactionID:r0732 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018495 +name: 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA." [UM-BBD_reactionID:r0192] +xref: UM-BBD_reactionID:r0192 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018496 +name: 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA." [UM-BBD_reactionID:r0205] +xref: UM-BBD_reactionID:r0205 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018497 +name: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS." [UM-BBD_reactionID:r0514] +synonym: "DDMS dehydrogenase activity" EXACT [] +xref: UM-BBD_reactionID:r0514 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018498 +name: 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate." [UM-BBD_enzymeID:e0308] +xref: MetaCyc:PHENPRODIOLDEHYDROG-RXN +xref: UM-BBD_enzymeID:e0308 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018499 +name: cis-2,3-dihydrodiol DDT dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT." [UM-BBD_reactionID:r0451] +xref: UM-BBD_reactionID:r0451 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018500 +name: trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene." [UM-BBD_reactionID:r0575] +xref: UM-BBD_reactionID:r0575 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018501 +name: cis-chlorobenzene dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol." [UM-BBD_enzymeID:e0411] +xref: UM-BBD_enzymeID:e0411 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018502 +name: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone." [UM-BBD_reactionID:r0553] +xref: MetaCyc:LINC-RXN +xref: UM-BBD_reactionID:r0553 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018503 +name: trans-1,2-dihydrodiolphenanthrene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene." [UM-BBD_reactionID:r0574] +xref: UM-BBD_reactionID:r0574 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018504 +name: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+." [EC:1.3.1.19] +synonym: "cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.19] +synonym: "cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity" EXACT [EC:1.3.1.19] +synonym: "cis-benzene glycol dehydrogenase activity" EXACT [EC:1.3.1.19] +xref: EC:1.3.1.19 +xref: MetaCyc:1.3.1.19-RXN +xref: UM-BBD_enzymeID:e0060 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018505 +name: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+." [EC:1.3.1.29] +synonym: "(+)-cis-naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] +synonym: "1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity" EXACT [] +synonym: "cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity" EXACT [EC:1.3.1.29] +synonym: "cis-dihydrodiol naphthalene dehydrogenase activity" EXACT [EC:1.3.1.29] +synonym: "cis-naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] +synonym: "naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] +xref: EC:1.3.1.29 +xref: MetaCyc:1.3.1.29-RXN +xref: RHEA:11832 +xref: UM-BBD_enzymeID:e0122 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018506 +name: maleylacetate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+." [EC:1.3.1.32] +synonym: "3-oxoadipate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.32] +synonym: "maleolylacetate reductase activity" EXACT [EC:1.3.1.32] +xref: EC:1.3.1.32 +xref: MetaCyc:MALEYLACETATE-REDUCTASE-RXN +xref: UM-BBD_enzymeID:e0063 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018507 +name: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol." [EC:1.3.1.49, RHEA:16253] +synonym: "(+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity" EXACT [EC:1.3.1.49] +synonym: "cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity" EXACT [] +xref: EC:1.3.1.49 +xref: KEGG_REACTION:R04151 +xref: MetaCyc:1.3.1.49-RXN +xref: RHEA:16253 +xref: UM-BBD_reactionID:r0488 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018508 +name: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+." [MetaCyc:BENZOATE-CIS-DIOL-DEHYDROGENASE-RXN] +synonym: "benzoate cis-diol dehydrogenase activity" EXACT [] +xref: UM-BBD_enzymeID:e0219 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018509 +name: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+." [EC:1.3.1.56] +synonym: "2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity" EXACT [] +synonym: "biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity" EXACT [EC:1.3.1.56] +synonym: "cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.56] +xref: EC:1.3.1.56 +xref: MetaCyc:1.3.1.56-RXN +xref: RHEA:17033 +xref: UM-BBD_enzymeID:e0134 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018510 +name: phloroglucinol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol." [EC:1.3.1.57, RHEA:10080] +synonym: "dihydrophloroglucinol:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.57] +xref: EC:1.3.1.57 +xref: KEGG_REACTION:R05308 +xref: MetaCyc:R5-RXN +xref: RHEA:10080 +xref: UM-BBD_reactionID:r0007 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018511 +name: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH." [EC:1.3.1.58, RHEA:23772] +synonym: "cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.58] +xref: EC:1.3.1.58 +xref: KEGG_REACTION:R05240 +xref: MetaCyc:RXN-665 +xref: RHEA:23772 +xref: UM-BBD_reactionID:r0396 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018512 +name: obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+." [EC:1.3.1.59] +comment: This term was made obsolete because, according to the Enzyme Commission, there is no evidence that this enzymatic activity exists. +synonym: "1,2-dihydroxy-3-methylcyclohexa-3,5-diene-carboxylate dehydrogenase activity" EXACT [] +synonym: "1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity" EXACT [] +xref: UM-BBD_reactionID:r0216 +is_obsolete: true + +[Term] +id: GO:0018513 +name: dibenzothiophene dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH." [EC:1.3.1.60, RHEA:24188] +synonym: "cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.60] +xref: EC:1.3.1.60 +xref: KEGG_REACTION:R05310 +xref: MetaCyc:1.3.1.60-RXN +xref: RHEA:24188 +xref: UM-BBD_reactionID:r0161 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018515 +name: pimeloyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH." [EC:1.3.1.62, RHEA:19665] +synonym: "pimeloyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.62] +xref: EC:1.3.1.62 +xref: KEGG_REACTION:R05311 +xref: MetaCyc:1.3.1.62-RXN +xref: RHEA:19665 +xref: UM-BBD_reactionID:r0194 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018516 +name: 2,4-dichlorobenzoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH." [EC:1.3.1.63, RHEA:23076] +synonym: "4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)" EXACT [EC:1.21.1.2] +xref: EC:1.21.1.2 +xref: KEGG_REACTION:R05276 +xref: MetaCyc:1.3.1.63-RXN +xref: RHEA:23076 +xref: UM-BBD_reactionID:r0138 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018517 +name: phthalate 4,5-cis-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH." [EC:1.3.1.64, RHEA:13837] +synonym: "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.64] +xref: EC:1.3.1.64 +xref: KEGG_REACTION:R05275 +xref: MetaCyc:1.3.1.64-RXN +xref: RHEA:13837 +xref: UM-BBD_reactionID:r0142 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018518 +name: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH." [EC:1.3.1.65, RHEA:24556] +synonym: "5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase" RELATED [] +synonym: "5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.65] +xref: EC:1.3.1.65 +xref: KEGG_REACTION:R05312 +xref: MetaCyc:RXN-643 +xref: RHEA:24556 +xref: UM-BBD_reactionID:r0053 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018519 +name: cis-dihydroethylcatechol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH." [EC:1.3.1.66, RHEA:18101] +synonym: "cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.66] +synonym: "cis-ethylbenzene glycol dehydrogenase activity" EXACT [] +xref: EC:1.3.1.66 +xref: KEGG_REACTION:R05313 +xref: MetaCyc:1.3.1.66-RXN +xref: RHEA:18101 +xref: UM-BBD_reactionID:r0309 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018520 +name: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2." [EC:1.3.1.67] +synonym: "4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity" EXACT [] +synonym: "cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.67] +xref: EC:1.3.1.67 +xref: MetaCyc:1.3.1.67-RXN +xref: UM-BBD_reactionID:r0179 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018521 +name: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH." [EC:1.3.1.68, RHEA:15657] +synonym: "1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.68] +xref: EC:1.3.1.68 +xref: KEGG_REACTION:R05314 +xref: MetaCyc:1.3.1.68-RXN +xref: RHEA:15657 +xref: UM-BBD_reactionID:r0224 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018522 +name: benzoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin." [EC:1.3.7.8] +synonym: "benzoyl-CoA reductase (dearomatizing) activity" EXACT [EC:1.3.7.8] +synonym: "cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity" EXACT [KEGG_REACTION:R02451] +xref: EC:1.3.7.8 +xref: KEGG_REACTION:R02451 +xref: MetaCyc:1.3.99.15-RXN +xref: UM-BBD_reactionID:r0190 +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0018523 +name: quinoline 2-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor." [EC:1.3.99.17] +synonym: "quinoline:acceptor 2-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.17] +xref: EC:1.3.99.17 +xref: MetaCyc:1.3.99.17-RXN +xref: UM-BBD_reactionID:r0045 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0018524 +name: acetophenone carboxylase activity +namespace: molecular_function +alt_id: GO:0018797 +def: "Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate." [UM-BBD_reactionID:r0033] +xref: EC:6.4.1 +xref: UM-BBD_reactionID:r0033 +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0018525 +name: 4-hydroxybenzoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin." [KEGG_REACTION:R05316] +synonym: "4-hydroxybenzoyl-coA reductase (dehydroxylating) activity" EXACT [EC:1.3.7.9] +synonym: "4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.7.9] +xref: EC:1.3.7.9 +xref: KEGG_REACTION:R05316 +xref: MetaCyc:OHBENZCOARED-RXN +xref: UM-BBD_reactionID:r0158 +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0018526 +name: 2-aminobenzoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA." [UM-BBD_reactionID:r0342] +xref: UM-BBD_reactionID:r0342 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0018527 +name: cyclohexylamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide." [EC:1.4.3.12] +synonym: "cyclohexylamine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.12] +xref: EC:1.4.3.12 +xref: MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN +xref: RHEA:18433 +xref: UM-BBD_reactionID:r0754 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0018528 +name: iminodiacetate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine." [UM-BBD_reactionID:r0589] +xref: UM-BBD_reactionID:r0589 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0018529 +name: nitrilotriacetate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate." [UM-BBD_reactionID:r0587] +xref: EC:1.14.14.10 +xref: UM-BBD_reactionID:r0587 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0018530 +name: (R)-6-hydroxynicotine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)." [EC:1.5.3.6, RHEA:10012] +synonym: "(R)-6-hydroxynicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.6] +synonym: "6-hydroxy-D-nicotine oxidase activity" EXACT [] +synonym: "D-6-hydroxynicotine oxidase activity" EXACT [EC:1.5.3.6] +xref: EC:1.5.3.6 +xref: KEGG_REACTION:R07170 +xref: MetaCyc:R-6-HYDROXYNICOTINE-OXIDASE-RXN +xref: RHEA:10012 +xref: UM-BBD_reactionID:r0477 +is_a: GO:0019116 ! hydroxy-nicotine oxidase activity + +[Term] +id: GO:0018531 +name: (S)-6-hydroxynicotine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)." [EC:1.5.3.5, RHEA:11880] +synonym: "(S)-6-hydroxynicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.5] +synonym: "6-hydroxy-L-nicotine oxidase activity" EXACT [] +synonym: "6-hydroxy-L-nicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.5] +synonym: "L-6-hydroxynicotine oxidase activity" EXACT [] +xref: EC:1.5.3.5 +xref: KEGG_REACTION:R03202 +xref: MetaCyc:S-6-HYDROXYNICOTINE-OXIDASE-RXN +xref: RHEA:11880 +xref: UM-BBD_reactionID:r0478 +is_a: GO:0019116 ! hydroxy-nicotine oxidase activity + +[Term] +id: GO:0018532 +name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin." [UM-BBD_reactionID:r0353] +synonym: "coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity" EXACT [] +synonym: "coenzyme F420-independent methylene-H4MPT dehydrogenase activity" EXACT [] +synonym: "F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity" EXACT [] +synonym: "F420-independent methylene-H4MPT dehydrogenase activity" EXACT [] +xref: EC:1.5.99 +xref: UM-BBD_reactionID:r0353 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0018533 +name: peptidyl-cysteine acetylation +namespace: biological_process +def: "The acetylation of peptidyl-cysteine." [GOC:mah] +is_a: GO:0006473 ! protein acetylation +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0018534 +name: nitrilotriacetate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate." [UM-BBD_reactionID:r0588] +xref: EC:1.5.99 +xref: UM-BBD_reactionID:r0588 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0018535 +name: nicotine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor." [EC:1.5.99.4] +synonym: "D-nicotine oxidase activity" EXACT [EC:1.5.99.4] +synonym: "nicotine oxidase activity" EXACT [EC:1.5.99.4] +synonym: "nicotine:(acceptor) 6-oxidoreductase (hydroxylating)" EXACT [EC:1.5.99.4] +synonym: "nicotine:acceptor 6-oxidoreductase (hydroxylating)" EXACT [EC:1.5.99.4] +xref: EC:1.5.99.4 +xref: MetaCyc:NICOTINE-DEHYDROGENASE-RXN +xref: RHEA:14769 +xref: UM-BBD_enzymeID:e0337 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0018537 +name: coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420." [EC:1.5.98.2, RHEA:21144] +synonym: "5,10-methylenetetrahydromethanopterin cyclohydrolase activity" EXACT [EC:1.5.98.2] +synonym: "5,10-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.98.2] +synonym: "5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.98.2] +synonym: "coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity" EXACT [EC:1.5.98.2] +synonym: "methylene-H(4)MPT reductase activity" EXACT [EC:1.5.98.2] +synonym: "methylene-H4MPT reductase activity" EXACT [EC:1.5.98.2] +synonym: "methylenetetrahydromethanopterin reductase activity" EXACT [] +synonym: "N(5),N(10)-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.98.2] +synonym: "N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.98.2] +synonym: "N5,N10-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.98.2] +synonym: "N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.98.2] +xref: EC:1.5.98.2 +xref: KEGG_REACTION:R04464 +xref: MetaCyc:METHELENE-THMPT-OXI-RXN +xref: RHEA:21144 +xref: UM-BBD_reactionID:r0354 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0018538 +name: epoxide carboxylase activity +namespace: molecular_function +def: "Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+." [PMID:9555888] +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0018541 +name: p-benzoquinone reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+)." [EC:1.6.5.6, RHEA:23488] +synonym: "NADPH:p-benzoquinone oxidoreductase activity" EXACT [EC:1.6.5.6] +xref: EC:1.6.5.6 +xref: KEGG_REACTION:R05244 +xref: MetaCyc:1.6.5.6-RXN +xref: RHEA:23488 +xref: UM-BBD_enzymeID:e0422 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0018542 +name: 2,3-dihydroxy DDT 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate." [UM-BBD_reactionID:r0452] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0452 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018543 +name: 4-amino-2-nitroso-6-nitrotoluene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene." [UM-BBD_reactionID:r0464] +xref: UM-BBD_reactionID:r0464 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0018544 +name: 4-carboxy-4'-sulfoazobenzene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate." [UM-BBD_reactionID:r0543] +synonym: "4-carboxy-4'-sulphoazobenzene reductase activity" EXACT [] +xref: UM-BBD_reactionID:r0543 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0018545 +name: NAD(P)H nitroreductase activity +namespace: molecular_function +def: "Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative." [UM-BBD_enzymeID:e0346] +xref: UM-BBD_enzymeID:e0346 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0018546 +name: nitrobenzene nitroreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O." [MetaCyc:RXN-8815] +xref: MetaCyc:RXN-8815 +xref: UM-BBD_enzymeID:e0245 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0018547 +name: nitroglycerin reductase activity +namespace: molecular_function +def: "Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative." [UM-BBD_enzymeID:e0038] +synonym: "NG reductase activity" EXACT [] +xref: UM-BBD_enzymeID:e0038 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor + +[Term] +id: GO:0018548 +name: pentaerythritol trinitrate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate." [UM-BBD_reactionID:r0025] +synonym: "xenobiotic reductase activity" BROAD [UM-BBD_enzymeID:e0028] +xref: EC:1.6.99.1 +xref: UM-BBD_reactionID:r0025 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0018549 +name: methanethiol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide." [EC:1.8.3.4] +synonym: "(MM)-oxidase activity" EXACT [EC:1.8.3.4] +synonym: "methanethiol:oxygen oxidoreductase activity" EXACT [EC:1.8.3.4] +synonym: "methyl mercaptan oxidase activity" EXACT [EC:1.8.3.4] +synonym: "methylmercaptan oxidase activity" EXACT [EC:1.8.3.4] +synonym: "MT-oxidase activity" EXACT [EC:1.8.3.4] +xref: EC:1.8.3.4 +xref: MetaCyc:METHANETHIOL-OXIDASE-RXN +xref: RHEA:11812 +xref: UM-BBD_reactionID:r0209 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0018550 +name: tetrachloro-p-hydroquinone reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl." [UM-BBD_reactionID:r0314] +synonym: "tetrachlorohydroquinone reductive dehalogenase activity" EXACT [] +xref: EC:1.8.99 +xref: UM-BBD_reactionID:r0314 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0018551 +name: hydrogensulfite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor." [EC:1.8.99.3] +synonym: "bisulfite reductase activity" EXACT [EC:1.8.99.3] +synonym: "desulfofuscidin activity" NARROW [EC:1.8.99.3] +synonym: "desulforubidin activity" NARROW [EC:1.8.99.3] +synonym: "desulfoviridin activity" NARROW [EC:1.8.99.3] +synonym: "dissimilatory sulfite reductase activity" EXACT [] +synonym: "dissimilatory-type sulfite reductase activity" EXACT [EC:1.8.99.3] +synonym: "hydrogensulphite reductase activity" EXACT [] +synonym: "trithionate:(acceptor) oxidoreductase activity" EXACT [EC:1.8.99.3] +synonym: "trithionate:acceptor oxidoreductase activity" EXACT [EC:1.8.99.3] +xref: EC:1.8.99.3 +xref: MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN +xref: RHEA:13209 +xref: UM-BBD_reactionID:r0627 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0018553 +name: 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate." [UM-BBD_enzymeID:e0309] +xref: UM-BBD_enzymeID:e0309 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0018554 +name: 1,2-dihydroxynaphthalene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached." [UM-BBD_enzymeID:e0255] +xref: EC:1.13.11.56 +xref: RHEA:27310 +xref: UM-BBD_enzymeID:e0255 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0018555 +name: phenanthrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene." [UM-BBD_reactionID:r0455] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0455 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018556 +name: 2,2',3-trihydroxybiphenyl dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate)." [UM-BBD_enzymeID:e0032] +xref: EC:1.13.11 +xref: UM-BBD_enzymeID:e0032 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018557 +name: 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid." [UM-BBD_reactionID:r0422] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0422 +is_a: GO:0019117 ! dihydroxyfluorene dioxygenase activity + +[Term] +id: GO:0018558 +name: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon." [UM-BBD_reactionID:r0049] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0049 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018559 +name: 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate." [UM-BBD_reactionID:r0442] +synonym: "1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity" EXACT [] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0442 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018560 +name: protocatechuate 3,4-dioxygenase type II activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate." [UM-BBD_reactionID:r0581] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0581 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018561 +name: 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate." [UM-BBD_reactionID:r0457] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0457 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018562 +name: 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid." [UM-BBD_reactionID:r0415] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0415 +is_a: GO:0019117 ! dihydroxyfluorene dioxygenase activity + +[Term] +id: GO:0018563 +name: 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate." [UM-BBD_reactionID:r0310] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0310 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018564 +name: carbazole 1,9a-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol." [UM-BBD_reactionID:r0456] +synonym: "carbazole 1,9alpha-dioxygenase activity" EXACT [] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0456 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018565 +name: dihydroxydibenzothiophene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate." [UM-BBD_reactionID:r0162] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0162 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018566 +name: 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate." [UM-BBD_reactionID:r0324] +synonym: "1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity" EXACT [] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0324 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018567 +name: styrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol." [UM-BBD_reactionID:r0256] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0256 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018568 +name: 3,4-dihydroxyphenanthrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate." [UM-BBD_reactionID:r0501] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0501 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018569 +name: hydroquinone 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde." [UM-BBD_reactionID:r0228] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0228 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018570 +name: p-cumate 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate." [UM-BBD_reactionID:r0395] +xref: EC:1.13.11 +xref: MetaCyc:RXN-664 +xref: UM-BBD_reactionID:r0395 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018571 +name: 2,3-dihydroxy-p-cumate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate." [MetaCyc:RXN-666, UM-BBD_reactionID:r0397] +synonym: "2,3-dihydroxy-p-cumate 3,4-dioxygenase" EXACT [] +synonym: "2,3-dihydroxy-p-cumate-3,4-dioxygenase" EXACT [] +xref: EC:1.13.11 +xref: MetaCyc:RXN-666 +xref: UM-BBD_reactionID:r0397 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018572 +name: 3,5-dichlorocatechol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate." [UM-BBD_reactionID:r0276] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0276 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018573 +name: 2-aminophenol 1,6-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde." [UM-BBD_reactionID:r0305] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0305 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018574 +name: 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate." [UM-BBD_enzymeID:e0422] +xref: EC:1.13.11 +xref: UM-BBD_enzymeID:e0422 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018575 +name: chlorocatechol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate." [UM-BBD_reactionID:r0655] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0655 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018576 +name: catechol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: catechol + O2 = cis,cis-muconate." [EC:1.13.11.1] +synonym: "1,2-pyrocatechase activity" EXACT [EC:1.13.11.1] +synonym: "catechase activity" RELATED [EC:1.13.11.1] +synonym: "catechol 1,2-oxygenase activity" EXACT [EC:1.13.11.1] +synonym: "catechol-oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.1] +synonym: "catechol:oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.1] +synonym: "CD I" RELATED [EC:1.13.11.1] +synonym: "CD II" RELATED [EC:1.13.11.1] +synonym: "pyrocatechase activity" RELATED [EC:1.13.11.1] +synonym: "pyrocatechol 1,2-dioxygenase activity" EXACT [EC:1.13.11.1] +xref: EC:1.13.11.1 +xref: MetaCyc:CATECHOL-12-DIOXYGENASE-RXN +xref: RHEA:23852 +xref: UM-BBD_enzymeID:e0064 +is_a: GO:0019114 ! catechol dioxygenase activity + +[Term] +id: GO:0018577 +name: catechol 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde." [EC:1.13.11.2] +synonym: "2,3-pyrocatechase activity" EXACT [EC:1.13.11.2] +synonym: "catechol 2,3-oxygenase" EXACT [EC:1.13.11.2] +synonym: "catechol oxygenase" EXACT [EC:1.13.11.2] +synonym: "catechol:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.2] +synonym: "cato2ase activity" RELATED [EC:1.13.11.2] +synonym: "metapyrocatechase activity" RELATED [EC:1.13.11.2] +synonym: "pyrocatechol 2,3-dioxygenase" EXACT [EC:1.13.11.2] +xref: EC:1.13.11.2 +xref: MetaCyc:CATECHOL-23-DIOXYGENASE-RXN +xref: RHEA:17337 +xref: UM-BBD_enzymeID:e0156 +is_a: GO:0019114 ! catechol dioxygenase activity + +[Term] +id: GO:0018578 +name: protocatechuate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate." [EC:1.13.11.3] +synonym: "protocatechuate oxygenase activity" BROAD [EC:1.13.11.3] +synonym: "protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.3] +synonym: "protocatechuic 3,4-dioxygenase activity" EXACT [EC:1.13.11.3] +synonym: "protocatechuic 3,4-oxygenase activity" EXACT [EC:1.13.11.3] +synonym: "protocatechuic acid oxidase activity" EXACT [EC:1.13.11.3] +xref: EC:1.13.11.3 +xref: MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN +xref: RHEA:10084 +xref: UM-BBD_reactionID:r0143 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018579 +name: protocatechuate 4,5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde." [EC:1.13.11.8] +synonym: "protocatechuate 4,5-oxygenase activity" EXACT [EC:1.13.11.8] +synonym: "protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.8] +synonym: "protocatechuic 4,5-dioxygenase activity" EXACT [EC:1.13.11.8] +synonym: "protocatechuic 4,5-oxygenase activity" EXACT [EC:1.13.11.8] +xref: EC:1.13.11.8 +xref: MetaCyc:PROTOCATECHUATE-45-DIOXYGENASE-RXN +xref: RHEA:24044 +xref: UM-BBD_reactionID:r0144 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018580 +name: nitronate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite." [EC:1.13.12.16, RHEA:28770] +comment: Where non-covalently bound FMN is used as the cofactor, see instead 'nitronate monooxygenase (FMN-linked) activity ; GO:0036434'. +synonym: "2-nitropropane dioxygenase activity" RELATED [EC:1.13.11.32] +synonym: "nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity" EXACT systematic_synonym [EC:1.13.12.16] +xref: EC:1.13.12.16 +xref: MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN +xref: RHEA:28770 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0018581 +name: hydroxyquinol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate." [EC:1.13.11.37] +synonym: "benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.37] +synonym: "hydroxyquinol dioxygenase activity" EXACT [EC:1.13.11.37] +xref: EC:1.13.11.37 +xref: MetaCyc:HYDROXYQUINOL-12-DIOXYGENASE-RXN +xref: RHEA:19441 +xref: UM-BBD_reactionID:r0232 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018582 +name: 1-hydroxy-2-naphthoate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate." [EC:1.13.11.38] +synonym: "1-hydroxy-2-naphthoate dioxygenase activity" EXACT [] +synonym: "1-hydroxy-2-naphthoate-degrading enzyme activity" NARROW [EC:1.13.11.38] +synonym: "1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.38] +synonym: "1-hydroxy-2-naphthoic acid dioxygenase activity" EXACT [EC:1.13.11.38] +xref: EC:1.13.11.38 +xref: MetaCyc:1.13.11.38-RXN +xref: RHEA:14749 +xref: UM-BBD_reactionID:r0486 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018583 +name: biphenyl-2,3-diol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O." [EC:1.13.11.39] +synonym: "2,3-dihydroxybiphenyl 1,2-dioxygenase activity" BROAD [] +synonym: "2,3-dihydroxybiphenyl dioxygenase activity" BROAD [EC:1.13.11.39] +synonym: "biphenyl-2,3-diol dioxygenase activity" EXACT [EC:1.13.11.39] +synonym: "biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.39] +xref: EC:1.13.11.39 +xref: MetaCyc:BIPHENYL-23-DIOL-12-DIOXYGENASE-RXN +xref: RHEA:14413 +xref: UM-BBD_enzymeID:e0127 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0018584 +name: 2,4,5-trichlorophenoxyacetic acid oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol." [UM-BBD_reactionID:r0359] +xref: EC:1.13.99 +xref: UM-BBD_reactionID:r0359 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0018585 +name: fluorene oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol." [UM-BBD_reactionID:r0407] +xref: UM-BBD_reactionID:r0407 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018586 +name: mono-butyltin dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin." [UM-BBD_reactionID:r0647] +synonym: "MBT dioxygenase activity" EXACT [] +xref: UM-BBD_reactionID:r0647 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018587 +name: obsolete limonene 8-monooxygenase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "limonene 8-monooxygenase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0019113 + +[Term] +id: GO:0018588 +name: tri-n-butyltin dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin." [UM-BBD_reactionID:r0643] +synonym: "TBT dioxygenase activity" EXACT [] +xref: UM-BBD_reactionID:r0643 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018589 +name: di-n-butyltin dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin." [UM-BBD_reactionID:r0645] +synonym: "DBT dioxygenase activity" EXACT [] +xref: UM-BBD_reactionID:r0645 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018590 +name: methylsilanetriol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol." [UM-BBD_reactionID:r0640] +xref: UM-BBD_reactionID:r0640 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018591 +name: methyl tertiary butyl ether 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde." [UM-BBD_reactionID:r1023] +synonym: "MTBE 3-monooxygenase activity" EXACT [] +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018592 +name: 4-nitrocatechol 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol." [UM-BBD_reactionID:r0231] +xref: EC:1.14.13.166 +xref: UM-BBD_reactionID:r0231 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018593 +name: 4-chlorophenoxyacetate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol." [UM-BBD_reactionID:r0281] +xref: UM-BBD_reactionID:r0281 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018594 +name: tert-butanol 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol." [UM-BBD_reactionID:r0615] +synonym: "tert-butyl alcohol 2-monooxygenase activity" EXACT [] +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018595 +name: alpha-pinene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol." [UM-BBD_reactionID:r0716] +xref: EC:1.14.13.155 +xref: RHEA:32891 +xref: UM-BBD_reactionID:r0716 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018596 +name: dimethylsilanediol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol." [UM-BBD_reactionID:r0637] +synonym: "DMSD hydroxylase activity" EXACT [] +xref: UM-BBD_reactionID:r0637 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018597 +name: ammonia monooxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions." [PMID:16347810] +xref: EC:1.14.99.39 +xref: RHEA:27341 +xref: UM-BBD_enzymeID:e0061 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018598 +name: hydroxymethylsilanetriol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol." [UM-BBD_reactionID:r0641] +xref: UM-BBD_reactionID:r0641 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018599 +name: 2-hydroxyisobutyrate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate." [UM-BBD_reactionID:r0619] +xref: UM-BBD_reactionID:r0619 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018600 +name: alpha-pinene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol." [UM-BBD_reactionID:r0709] +xref: EC:1.14 +xref: UM-BBD_reactionID:r0709 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018601 +name: 4-nitrophenol 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+)." [EC:1.14.13.29, RHEA:12568] +synonym: "4-nitrophenol hydroxylase activity" EXACT [EC:1.14.13.29] +synonym: "4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.29] +synonym: "4-nitrophenol-2-hydroxylase activity" EXACT [EC:1.14.13.29] +xref: EC:1.14.13.29 +xref: KEGG_REACTION:R03023 +xref: MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN +xref: RHEA:12568 +xref: UM-BBD_reactionID:r0230 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018602 +name: 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2." [UM-BBD_reactionID:r0274] +xref: MetaCyc:RXN-9863 +xref: UM-BBD_reactionID:r0274 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0018603 +name: nitrobenzene 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol." [UM-BBD_reactionID:r0306] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0306 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018604 +name: 4-aminobenzoate 3,4-dioxygenase (deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate." [UM-BBD_reactionID:r0566] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0566 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018606 +name: benzenesulfonate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol." [UM-BBD_reactionID:r0295] +synonym: "benzenesulphonate dioxygenase activity" EXACT [] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0295 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018607 +name: 1-indanone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin." [UM-BBD_reactionID:r0417] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0417 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018608 +name: 1-indanone dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone." [UM-BBD_reactionID:r0416] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0416 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018609 +name: chlorobenzene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene)." [UM-BBD_enzymeID:e0062] +xref: EC:1.14.12 +xref: UM-BBD_enzymeID:e0062 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018610 +name: dibenzofuran 4,4a-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+." [MetaCyc:R606-RXN] +xref: EC:1.14.12 +xref: MetaCyc:R606-RXN +xref: UM-BBD_enzymeID:e0030 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018611 +name: toluate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate." [UM-BBD_enzymeID:e0190] +xref: EC:1.14.12 +xref: UM-BBD_enzymeID:e0190 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018612 +name: dibenzothiophene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene." [UM-BBD_reactionID:r0160] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0160 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018613 +name: 9-fluorenone dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone." [UM-BBD_reactionID:r0409] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0409 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018614 +name: ethylbenzene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene." [UM-BBD_reactionID:r0247] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0247 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018615 +name: 2-indanone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone." [UM-BBD_reactionID:r0424] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0424 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018616 +name: trihydroxytoluene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate." [MetaCyc:R305-RXN, UM-BBD_reactionID:r0093] +xref: EC:1.14.12 +xref: MetaCyc:R305-RXN +xref: UM-BBD_reactionID:r0093 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018617 +name: 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol." [UM-BBD_reactionID:r0580] +synonym: "4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity" EXACT [] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0580 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018618 +name: anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3." [EC:1.14.12.1] +synonym: "AntA" RELATED [] +synonym: "AntB" RELATED [] +synonym: "AntC" RELATED [] +synonym: "anthranilate 1,2-dioxygenase" RELATED [] +synonym: "anthranilate dioxygenase activity" EXACT [] +synonym: "anthranilate dioxygenase reductase" NARROW [] +synonym: "anthranilate hydroxylase activity" BROAD [EC:1.14.12.1] +synonym: "anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)" EXACT [EC:1.14.12.1] +synonym: "anthranilic acid hydroxylase activity" BROAD [EC:1.14.12.1] +synonym: "anthranilic hydroxylase activity" BROAD [EC:1.14.12.1] +xref: EC:1.14.12.1 +xref: MetaCyc:1.14.12.1-RXN +xref: UM-BBD_reactionID:r0577 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018619 +name: benzene 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+)." [EC:1.14.12.3, RHEA:13813] +synonym: "benzene dioxygenase activity" EXACT [EC:1.14.12.3] +synonym: "benzene hydroxylase activity" RELATED [EC:1.14.12.3] +synonym: "benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.3] +xref: EC:1.14.12.3 +xref: KEGG_REACTION:R03543 +xref: MetaCyc:BENZENE-12-DIOXYGENASE-RXN +xref: RHEA:13813 +xref: UM-BBD_reactionID:r0079 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018620 +name: phthalate 4,5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)." [EC:1.14.12.7, RHEA:17489] +synonym: "PDO activity" EXACT [EC:1.14.12.7] +synonym: "phthalate dioxygenase activity" BROAD [EC:1.14.12.7] +synonym: "phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)" EXACT [EC:1.14.12.7] +xref: EC:1.14.12.7 +xref: KEGG_REACTION:R03630 +xref: MetaCyc:PHTHALATE-45-DIOXYGENASE-RXN +xref: RHEA:17489 +xref: UM-BBD_reactionID:r0102 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018621 +name: 4-sulfobenzoate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite." [EC:1.14.12.8, RHEA:13937] +synonym: "4-sulfobenzoate 3,4-dioxygenase system" RELATED [EC:1.14.12.8] +synonym: "4-sulfobenzoate dioxygenase activity" EXACT [EC:1.14.12.8] +synonym: "4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)" EXACT [EC:1.14.12.8] +synonym: "4-sulphobenzoate 3,4-dioxygenase activity" EXACT [] +xref: EC:1.14.12.8 +xref: KEGG_REACTION:R01636 +xref: MetaCyc:4-SULFOBENZOATE-34-DIOXYGENASE-RXN +xref: RHEA:13937 +xref: UM-BBD_reactionID:r0293 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018622 +name: 4-chlorophenylacetate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+)." [EC:1.14.12.9, RHEA:14689] +synonym: "4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)" EXACT [EC:1.14.12.9] +xref: EC:1.14.12.9 +xref: KEGG_REACTION:R03306 +xref: MetaCyc:1.14.12.9-RXN +xref: RHEA:14689 +xref: UM-BBD_reactionID:r0308 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018623 +name: benzoate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+." [EC:1.14.12.10] +synonym: "benzoate dioxygenase activity" EXACT [EC:1.14.12.10] +synonym: "benzoate hydroxylase activity" EXACT [EC:1.14.12.10] +synonym: "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.10] +synonym: "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)" EXACT [EC:1.14.12.10] +synonym: "benzoic hydroxylase activity" EXACT [EC:1.14.12.10] +xref: EC:1.14.12.10 +xref: MetaCyc:BENZOATE-12-DIOXYGENASE-RXN +xref: RHEA:12633 +xref: UM-BBD_enzymeID:e0154 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018624 +name: toluene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)." [EC:1.14.12.11, RHEA:16737] +synonym: "toluene 1,2-dioxygenase activity" EXACT [EC:1.14.12.11] +synonym: "toluene 2,3-dioxygenase activity" EXACT [EC:1.14.12.11] +synonym: "toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.11] +xref: EC:1.14.12.11 +xref: KEGG_REACTION:R03559 +xref: MetaCyc:TOLUENE-DIOXYGENASE-RXN +xref: RHEA:16737 +xref: UM-BBD_enzymeID:e0155 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018625 +name: naphthalene 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+." [EC:1.14.12.12] +synonym: "naphthalene dioxygenase activity" EXACT [EC:1.14.12.12] +synonym: "naphthalene oxygenase activity" EXACT [EC:1.14.12.12] +synonym: "naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.12] +xref: EC:1.14.12.12 +xref: MetaCyc:NAPHTHALENE-12-DIOXYGENASE-RXN +xref: RHEA:19173 +xref: UM-BBD_enzymeID:e0002 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018626 +name: 2-chlorobenzoate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2." [EC:1.14.12.13] +synonym: "2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)" EXACT [EC:1.14.12.13] +synonym: "2-halobenzoate 1,2-dioxygenase activity" EXACT [] +xref: EC:1.14.12.13 +xref: MetaCyc:2-CHLOROBENZOATE-12-DIOXYGENASE-RXN +xref: RHEA:21652 +xref: UM-BBD_reactionID:r0632 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018627 +name: 2-aminobenzenesulfonate 2,3-dioxygenase activity +namespace: molecular_function +alt_id: GO:0018605 +def: "Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol." [EC:1.14.12.14, RHEA:23468] +synonym: "2-aminobenzenesulfonate dioxygenase activity" EXACT [] +synonym: "2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)" EXACT [EC:1.14.12.14] +synonym: "2-aminobenzenesulphonate 2,3-dioxygenase activity" EXACT [] +synonym: "2-aminobenzenesulphonate dioxygenase activity" EXACT [] +synonym: "2-aminosulfobenzene 2,3-dioxygenase activity" EXACT [EC:1.14.12.14] +xref: EC:1.14.12.14 +xref: KEGG_REACTION:R05156 +xref: MetaCyc:2ASDOSALCAL-RXN +xref: RHEA:23468 +xref: UM-BBD_reactionID:r0218 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018628 +name: terephthalate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)." [EC:1.14.12.15, RHEA:10312] +synonym: "1,4-dicarboxybenzoate 1,2-dioxygenase activity" EXACT [EC:1.14.12.15] +synonym: "benzene-1,4-dicarboxylate 1,2-dioxygenase activity" EXACT [EC:1.14.12.15] +synonym: "benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.15] +xref: EC:1.14.12.15 +xref: KEGG_REACTION:R05148 +xref: MetaCyc:1.14.12.15-RXN +xref: RHEA:10312 +xref: UM-BBD_reactionID:r0150 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018629 +name: 2-hydroxyquinoline 5,6-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+." [EC:1.14.12.16] +synonym: "2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity" EXACT [] +synonym: "quinolin-2(1H)-one 5,6-dioxygenase activity" EXACT [EC:1.14.12.16] +synonym: "quinolin-2-ol 5,6-dioxygenase activity" EXACT [EC:1.14.12.16] +synonym: "quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)" EXACT [EC:1.14.12.16] +xref: EC:1.14.12.16 +xref: MetaCyc:1.14.12.16-RXN +xref: RHEA:10976 +xref: UM-BBD_reactionID:r0052 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018630 +name: 3,5-xylenol methylhydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol." [UM-BBD_reactionID:r0081] +xref: EC:1.14.13 +xref: MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN +xref: UM-BBD_reactionID:r0081 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018631 +name: phenylacetate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate." [UM-BBD_reactionID:r0036] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0036 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018632 +name: 4-nitrophenol 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone." [UM-BBD_reactionID:r0226] +xref: EC:1.14.13 +xref: MetaCyc:RXN-8739 +xref: UM-BBD_reactionID:r0226 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018633 +name: dimethyl sulfide monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde." [UM-BBD_reactionID:r0208] +synonym: "dimethyl sulphide monooxygenase activity" EXACT [] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0208 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018634 +name: alpha-pinene monooxygenase [NADH] activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide." [UM-BBD_reactionID:r0742] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0742 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018635 +name: (R)-limonene 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide." [UM-BBD_enzymeID:e0462] +synonym: "(+)-limonene 1,2-monooxygenase activity" EXACT [EC:1.14.13.107] +synonym: "(+)-limonene,NAD(P)H:oxygen oxidoreductase activity" EXACT systematic_synonym [EC:1.14.13.107] +synonym: "(R)-limonene,NAD(P)H:oxygen oxidoreductase activity" EXACT systematic_synonym [EC:1.14.13.107] +xref: EC:1.14.13.107 +xref: KEGG_REACTION:R06398 "limonene,NADH:oxygen oxidoreductase" +xref: KEGG_REACTION:R09393 "limonene,NADPH:oxygen oxidoreductase" +xref: MetaCyc:RXN-9407 +xref: RHEA:26093 +xref: RHEA:26097 +xref: UM-BBD_reactionID:r0733 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0018636 +name: phenanthrene 9,10-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide." [UM-BBD_reactionID:r0495] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0495 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018637 +name: 1-hydroxy-2-naphthoate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene." [UM-BBD_reactionID:r0491] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0491 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018638 +name: toluene 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene." [UM-BBD_enzymeID:e0225] +xref: EC:1.14.13 +xref: UM-BBD_enzymeID:e0225 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018639 +name: xylene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol." [UM-BBD_enzymeID:e0172] +xref: EC:1.14.13 +xref: UM-BBD_enzymeID:e0172 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018640 +name: dibenzothiophene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O." [MetaCyc:RXN-621] +xref: EC:1.14.13 +xref: MetaCyc:RXN-621 +xref: UM-BBD_enzymeID:e0214 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018641 +name: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline." [UM-BBD_reactionID:r0048] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0048 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018642 +name: chlorophenol 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol." [UM-BBD_enzymeID:e0252] +xref: EC:1.14.13 +xref: UM-BBD_enzymeID:e0252 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018643 +name: carbon disulfide oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide." [UM-BBD_reactionID:r0599] +synonym: "carbon disulphide oxygenase activity" EXACT [] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0599 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018644 +name: toluene 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene." [UM-BBD_enzymeID:e0222] +xref: EC:1.14.13 +xref: MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN +xref: UM-BBD_enzymeID:e0222 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018645 +name: alkene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O." [EC:1.14.13.69] +synonym: "alkene epoxygenase activity" EXACT [EC:1.14.13.69] +synonym: "alkene,NADH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.69] +xref: EC:1.14.13.69 +xref: MetaCyc:1.14.13.69-RXN +xref: RHEA:11792 +xref: UM-BBD_enzymeID:e0039 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018646 +name: 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate." [UM-BBD_reactionID:r0736] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0736 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018647 +name: phenanthrene 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide." [UM-BBD_enzymeID:e0333] +xref: EC:1.14.13 +xref: UM-BBD_enzymeID:e0333 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018648 +name: methanesulfonate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O." [EC:1.14.13.111] +synonym: "mesylate monooxygenase activity" EXACT [EC:1.14.13.111] +synonym: "methanesulfonate,FMNH2:oxygen oxidoreductase activity" EXACT [EC:1.14.13.111] +synonym: "methanesulfonate,NADH:oxygen oxidoreductase activity" EXACT systematic_synonym [EC:1.14.13.111] +synonym: "methanesulfonic acid monooxygenase activity" EXACT [EC:1.14.13.111] +synonym: "methanesulphonic acid monooxygenase activity" EXACT [GOC:mah] +synonym: "MSA monooxygenase activity" EXACT [EC:1.14.13.111] +synonym: "MSAMO activity" EXACT [EC:1.14.13.111] +xref: EC:1.14.13.111 +xref: MetaCyc:RXN-9770 +xref: RHEA:26077 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018649 +name: tetrahydrofuran hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran." [UM-BBD_reactionID:r0017] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0017 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018650 +name: styrene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide." [UM-BBD_reactionID:r0225] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0225 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018651 +name: toluene-4-sulfonate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene." [UM-BBD_reactionID:r0296] +synonym: "toluene-4-sulphonate monooxygenase activity" EXACT [] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0296 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018652 +name: toluene-sulfonate methyl-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol." [UM-BBD_reactionID:r0290] +synonym: "toluene-sulphonate methyl-monooxygenase activity" EXACT [] +xref: EC:1.14.13 +xref: MetaCyc:TSMOS-RXN +xref: UM-BBD_reactionID:r0290 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018653 +name: 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline." [EC:1.14.13.-] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0046 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018654 +name: 2-hydroxy-phenylacetate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate." [UM-BBD_reactionID:r0252] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0252 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018655 +name: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA." [UM-BBD_reactionID:r0430] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0430 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018656 +name: phenanthrene 3,4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide." [UM-BBD_reactionID:r0508] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0508 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018657 +name: toluene 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene." [UM-BBD_enzymeID:e0224] +xref: EC:1.14.13 +xref: MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN +xref: UM-BBD_enzymeID:e0224 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018658 +name: salicylate 1-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2." [EC:1.14.13.1] +synonym: "salicylate 1-hydroxylase activity" EXACT [EC:1.14.13.1] +synonym: "salicylate hydroxylase (decarboxylating)" EXACT [EC:1.14.13.1] +synonym: "salicylate hydroxylase activity" EXACT [] +synonym: "salicylate monooxygenase activity" EXACT [EC:1.14.13.1] +synonym: "salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.1] +synonym: "salicylic hydroxylase activity" EXACT [EC:1.14.13.1] +xref: EC:1.14.13.1 +xref: MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN +xref: RHEA:11004 +xref: UM-BBD_enzymeID:e0149 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018659 +name: 4-hydroxybenzoate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O." [EC:1.14.13.2] +synonym: "4-hydroxybenzoate 3-hydroxylase activity" BROAD [EC:1.14.13.2] +synonym: "4-hydroxybenzoate monooxygenase activity" EXACT [EC:1.14.13.2] +synonym: "4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.2] +synonym: "p-hydroxybenzoate hydrolyase activity" EXACT [EC:1.14.13.2] +synonym: "p-hydroxybenzoate hydroxylase activity" BROAD [EC:1.14.13.2] +synonym: "p-hydroxybenzoate-3-hydroxylase activity" EXACT [EC:1.14.13.2] +synonym: "p-hydroxybenzoic acid hydrolase activity" EXACT [EC:1.14.13.2] +synonym: "p-hydroxybenzoic acid hydroxylase activity" BROAD [EC:1.14.13.2] +synonym: "p-hydroxybenzoic hydroxylase activity" EXACT [EC:1.14.13.2] +synonym: "para-hydroxybenzoate hydroxylase activity" BROAD [EC:1.14.13.2] +xref: EC:1.14.13.2 +xref: MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN +xref: RHEA:19477 +xref: UM-BBD_reactionID:r0109 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018660 +name: 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O." [KEGG_REACTION:R02698] +synonym: "4 HPA 3-hydroxylase activity" BROAD [EC:1.14.13.3] +synonym: "4-hydroxyphenylacetate 3-hydroxylase activity" BROAD [] +synonym: "4-hydroxyphenylacetate 3-monooxygenase activity" BROAD [EC:1.14.13.3] +synonym: "p-hydroxyphenylacetate 3-hydroxylase activity" BROAD [EC:1.14.13.3] +synonym: "p-hydroxyphenylacetate hydroxylase activity" BROAD [EC:1.14.13.3] +xref: EC:1.14.13 +xref: KEGG_REACTION:R02698 +xref: RHEA:16681 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018661 +name: orcinol 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+)." [EC:1.14.13.6, RHEA:19601] +synonym: "orcinol hydroxylase activity" EXACT [] +synonym: "orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.6] +xref: EC:1.14.13.6 +xref: KEGG_REACTION:R02830 +xref: MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN +xref: RHEA:19601 +xref: UM-BBD_reactionID:r0092 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018662 +name: phenol 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O." [EC:1.14.13.7] +synonym: "phenol hydroxylase activity" EXACT [EC:1.14.13.7] +synonym: "phenol o-hydroxylase activity" EXACT [EC:1.14.13.7] +synonym: "phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.7] +xref: EC:1.14.13.7 +xref: MetaCyc:PHENOL-2-MONOOXYGENASE-RXN +xref: RHEA:17061 +xref: UM-BBD_enzymeID:e0208 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018663 +name: 2,6-dihydroxypyridine 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+)." [EC:1.14.13.10, RHEA:16917] +synonym: "2,6-dihydroxypyridine oxidase activity" EXACT [] +synonym: "2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.10] +xref: EC:1.14.13.10 +xref: KEGG_REACTION:R04130 +xref: MetaCyc:1.14.13.10-RXN +xref: RHEA:16917 +xref: UM-BBD_reactionID:r0479 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018664 +name: benzoate 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+)." [EC:1.14.14.92, RHEA:18033] +synonym: "4-hydroxybenzoic hydroxylase activity" EXACT [] +synonym: "benzoate 4-hydroxylase activity" EXACT [EC:1.14.14.92] +synonym: "benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.14.92] +synonym: "benzoate-p-hydroxylase activity" EXACT [EC:1.14.14.92] +synonym: "benzoate-para-hydroxylase activity" EXACT [EC:1.14.14.92] +synonym: "benzoic 4-hydroxylase activity" EXACT [EC:1.14.14.92] +synonym: "benzoic acid 4-hydroxylase activity" EXACT [EC:1.14.14.92] +synonym: "p-hydroxybenzoate hydroxylase activity" EXACT [EC:1.14.14.92] +xref: EC:1.14.14.92 +xref: KEGG_REACTION:R01295 +xref: MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN +xref: RHEA:18033 +xref: UM-BBD_reactionID:r0623 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018665 +name: 4-hydroxyphenylacetate 1-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O." [EC:1.14.13.18] +synonym: "4-HPA 1-hydroxylase activity" EXACT [EC:1.14.13.18] +synonym: "4-hydroxyphenyl-acetate 1-hydroxylase activity" EXACT [] +synonym: "4-hydroxyphenylacetate 1-hydroxylase activity" EXACT [EC:1.14.13.18] +synonym: "4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)" EXACT [EC:1.14.13.18] +synonym: "4-hydroxyphenylacetic 1-hydroxylase activity" EXACT [EC:1.14.13.18] +xref: EC:1.14.13.18 +xref: MetaCyc:1.14.13.18-RXN +xref: UM-BBD_reactionID:r0300 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018666 +name: 2,4-dichlorophenol 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O." [EC:1.14.13.20] +synonym: "2,4-dichlorophenol hydroxylase activity" EXACT [] +synonym: "2,4-dichlorophenol monooxygenase activity" EXACT [EC:1.14.13.20] +synonym: "2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.20] +xref: EC:1.14.13.20 +xref: MetaCyc:24-DICHLOROPHENOL-6-MONOOXYGENASE-RXN +xref: RHEA:20920 +xref: UM-BBD_enzymeID:e0152 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018667 +name: cyclohexanone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O." [EC:1.14.13.22] +synonym: "cyclohexanone 1,2-monooxygenase activity" EXACT [] +synonym: "cyclohexanone oxygenase activity" EXACT [EC:1.14.13.22] +synonym: "cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity" EXACT [EC:1.14.13.22] +synonym: "cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)" EXACT [EC:1.14.13.22] +xref: EC:1.14.13.22 +xref: MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN +xref: RHEA:24068 +xref: UM-BBD_reactionID:r0166 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018668 +name: 3-hydroxybenzoate 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+)." [EC:1.14.13.23, RHEA:11480] +synonym: "3-hydroxybenzoate 4-hydroxylase activity" EXACT [] +synonym: "3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.13.23] +xref: EC:1.14.13.23 +xref: KEGG_REACTION:R01628 +xref: MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN +xref: RHEA:11480 +xref: UM-BBD_reactionID:r0153 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018669 +name: 3-hydroxybenzoate 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+)." [EC:1.14.13.24, RHEA:22692] +synonym: "3-hydroxybenzoate 6-hydroxylase activity" EXACT [] +synonym: "3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.24] +synonym: "3-hydroxybenzoic acid-6-hydroxylase activity" EXACT [EC:1.14.13.24] +synonym: "m-hydroxybenzoate 6-hydroxylase activity" EXACT [EC:1.14.13.24] +xref: EC:1.14.13.24 +xref: KEGG_REACTION:R02589 +xref: MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN +xref: RHEA:22692 +xref: UM-BBD_reactionID:r0402 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018670 +name: 4-aminobenzoate 1-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2." [EC:1.14.13.27] +synonym: "4-aminobenzoate dehydrogenase activity" EXACT [EC:1.14.13.27] +synonym: "4-aminobenzoate hydroxylase activity" EXACT [] +synonym: "4-aminobenzoate monooxygenase activity" EXACT [EC:1.14.13.27] +synonym: "4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.27] +xref: EC:1.14.13.27 +xref: MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN +xref: UM-BBD_reactionID:r0597 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018671 +name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O." [EC:1.14.13.33] +synonym: "4-hydroxybenzoate 3-hydroxylase activity" BROAD [EC:1.14.13.33] +synonym: "4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))" EXACT [] +synonym: "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.33] +synonym: "4-hydroxybenzoate-3-hydroxylase activity" EXACT [EC:1.14.13.33] +xref: EC:1.14.13.33 +xref: MetaCyc:1.14.13.33-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018672 +name: anthranilate 3-monooxygenase (deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+)." [EC:1.14.13.35, RHEA:21236] +synonym: "anthranilate 2,3-dioxygenase (deaminating)" EXACT [EC:1.14.13.35] +synonym: "anthranilate 2,3-hydroxylase (deaminating) activity" EXACT [EC:1.14.13.35] +synonym: "anthranilate hydroxylase (deaminating) activity" EXACT [] +synonym: "anthranilate hydroxylase activity" BROAD [EC:1.14.13.35] +synonym: "anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)" EXACT [EC:1.14.13.35] +xref: EC:1.14.13.35 +xref: KEGG_REACTION:R00980 +xref: MetaCyc:1.14.13.35-RXN +xref: RHEA:21236 +xref: UM-BBD_reactionID:r0578 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018673 +name: anthraniloyl-CoA monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+." [EC:1.14.13.40] +synonym: "2-aminobenzoyl-CoA monooxygenase/reductase activity" EXACT [EC:1.14.13.40] +synonym: "2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)" EXACT [EC:1.14.13.40] +synonym: "anthraniloyl coenzyme A reductase activity" EXACT [EC:1.14.13.40] +xref: EC:1.14.13.40 +xref: MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN +xref: UM-BBD_reactionID:r0568 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018674 +name: (S)-limonene 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+)." [EC:1.14.14.99, RHEA:15129] +synonym: "(-)-limonene 3-hydroxylase activity" EXACT [EC:1.14.14.99] +synonym: "(-)-limonene 3-monooxygenase activity" EXACT [] +synonym: "(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.14.99] +synonym: "(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.14.99] +synonym: "limonene 3-hydroxylase activity" EXACT [] +xref: EC:1.14.14.99 +xref: KEGG_REACTION:R02469 +xref: MetaCyc:--LIMONENE-3-MONOOXYGENASE-RXN +xref: RHEA:15129 +xref: UM-BBD_reactionID:r0739 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0018675 +name: (S)-limonene 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O." [EC:1.14.14.51] +synonym: "(-)-limonene 6-hydroxylase activity" EXACT [EC:1.14.14.51] +synonym: "(-)-limonene 6-monooxygenase activity" EXACT [] +synonym: "(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity" EXACT [EC:1.14.14.51] +synonym: "(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.14.51] +synonym: "limonene 6-hydroxylase activity" EXACT [] +xref: EC:1.14.14.51 +xref: MetaCyc:--LIMONENE-6-MONOOXYGENASE-RXN +xref: RHEA:17945 +xref: UM-BBD_reactionID:r0713 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0018676 +name: (S)-limonene 7-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+)." [EC:1.14.14.52, RHEA:23432] +synonym: "(-)-limonene 7-monooxygenase activity" EXACT [] +xref: EC:1.14.14.52 +xref: KEGG_REACTION:R02470 +xref: MetaCyc:--LIMONENE-7-MONOOXYGENASE-RXN +xref: RHEA:23432 +xref: UM-BBD_reactionID:r0728 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0018677 +name: pentachlorophenol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride." [EC:1.14.13.50] +synonym: "PCB 4-monooxygenase activity" EXACT [EC:1.14.13.50] +synonym: "PCB4MO activity" EXACT [EC:1.14.13.50] +synonym: "PCP hydroxylase activity" EXACT [EC:1.14.13.50] +synonym: "PcpB" RELATED [EC:1.14.13.50] +synonym: "pentachlorophenol 4-monooxygenase activity" EXACT [] +synonym: "pentachlorophenol dechlorinase activity" EXACT [EC:1.14.13.50] +synonym: "pentachlorophenol dehalogenase activity" EXACT [EC:1.14.13.50] +synonym: "pentachlorophenol hydroxylase activity" EXACT [] +synonym: "pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)" EXACT [EC:1.14.13.50] +xref: EC:1.14.13.50 +xref: MetaCyc:PCP4MONO-RXN +xref: UM-BBD_enzymeID:e0148 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018678 +name: 4-hydroxybenzoate 1-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2." [EC:1.14.13.64] +synonym: "4-hydroxybenzoate 1-monooxygenase activity" EXACT [] +synonym: "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.64] +xref: EC:1.14.13.64 +xref: MetaCyc:1.14.13.64-RXN +xref: UM-BBD_reactionID:r0752 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018679 +name: dibenzothiophene-5,5-dioxide monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate." [UM-BBD_reactionID:r0235] +xref: EC:1.14.14 +xref: MetaCyc:RXN-623 +xref: UM-BBD_reactionID:r0235 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018680 +name: deethylatrazine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine." [UM-BBD_reactionID:r0128] +xref: EC:1.14.15 +xref: UM-BBD_reactionID:r0128 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018681 +name: deisopropylatrazine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine." [KEGG_REACTION:R05567] +xref: EC:1.14.15 +xref: KEGG_REACTION:R05567 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018682 +name: atrazine N-dealkylase activity +namespace: molecular_function +def: "Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O." [MetaCyc:R461-RXN, UM-BBD_reactionID:r0127] +synonym: "atrazine monooxygenase activity" RELATED [UM-BBD_enzymeID:e0090] +xref: EC:1.14.15 +xref: MetaCyc:R461-RXN +xref: UM-BBD_reactionID:r0127 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018683 +name: camphor 5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O." [EC:1.14.15.1] +synonym: "(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.15.1] +synonym: "2-bornanone 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "bornanone 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "camphor 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "camphor 5-exo-methylene hydroxylase activity" EXACT [] +synonym: "camphor 5-exohydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "camphor hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "camphor methylene hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "cytochrome p450-cam activity" EXACT [EC:1.14.15.1] +synonym: "d-camphor monooxygenase activity" EXACT [EC:1.14.15.1] +synonym: "D-camphor-exo-hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "methylene hydroxylase activity" EXACT [EC:1.14.15.1] +synonym: "methylene monooxygenase activity" EXACT [EC:1.14.15.1] +xref: EC:1.14.15.1 +xref: MetaCyc:R541-RXN +xref: UM-BBD_enzymeID:e0300 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018684 +name: camphor 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O." [EC:1.14.15.2] +synonym: "(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)" EXACT [EC:1.14.15.2] +synonym: "2,5-diketocamphane lactonizing enzyme activity" EXACT [EC:1.14.15.2] +synonym: "camphor ketolactonase I activity" EXACT [EC:1.14.15.2] +synonym: "ketolactonase I" RELATED [EC:1.14.15.2] +synonym: "oxygenase, camphor 1,2-mono" EXACT [EC:1.14.15.2] +xref: EC:1.14.15.2 +xref: MetaCyc:CAMPHOR-12-MONOOXYGENASE-RXN +xref: UM-BBD_enzymeID:e0302 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018685 +name: alkane 1-monooxygenase activity +namespace: molecular_function +alt_id: GO:0008393 +def: "Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O." [EC:1.14.15.3] +synonym: "1-hydroxylase activity" EXACT [EC:1.14.15.3] +synonym: "alkane 1-hydroxylase activity" EXACT [] +synonym: "alkane hydroxylase activity" EXACT [EC:1.14.15.3] +synonym: "alkane monooxygenase activity" EXACT [EC:1.14.15.3] +synonym: "alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity" EXACT [EC:1.14.15.3] +synonym: "fatty acid (omega-1)-hydroxylase activity" EXACT [] +synonym: "fatty acid omega-hydroxylase activity" NARROW [EC:1.14.15.3] +synonym: "lauric acid omega-hydroxylase activity" NARROW [EC:1.14.15.3] +synonym: "omega-hydroxylase activity" RELATED [EC:1.14.15.3] +xref: EC:1.14.15.3 +xref: MetaCyc:ALKANE-1-MONOOXYGENASE-RXN +xref: UM-BBD_enzymeID:e0022 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018686 +name: 6-hydroxy pseudo-oxynicotine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine." [UM-BBD_reactionID:r0480] +xref: EC:1.14.18 +xref: UM-BBD_reactionID:r0480 +is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0018687 +name: biphenyl 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+." [EC:1.14.12.18] +synonym: "biphenyl dioxygenase activity" EXACT [EC:1.14.12.18] +synonym: "biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)" EXACT [EC:1.14.12.18] +xref: EC:1.14.12.18 +xref: MetaCyc:1.14.12.18-RXN +xref: RHEA:18165 +xref: UM-BBD_enzymeID:e0089 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0018688 +name: DDT 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT." [UM-BBD_reactionID:r0450] +xref: EC:1.14.99 +xref: UM-BBD_reactionID:r0450 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0018689 +name: naphthalene disulfonate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene)." [UM-BBD_enzymeID:e0249] +synonym: "naphthalene disulphonate 1,2-dioxygenase activity" EXACT [] +xref: EC:1.14.99 +xref: UM-BBD_enzymeID:e0249 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018690 +name: 4-methoxybenzoate monooxygenase (O-demethylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O." [EC:1.14.99.15, RHEA:18613] +synonym: "4-methoxybenzoate 4-monooxygenase (O-demethylating)" EXACT [EC:1.14.99.15] +synonym: "4-methoxybenzoate monooxygenase activity" EXACT [] +synonym: "4-methoxybenzoate O-demethylase activity" EXACT [EC:1.14.99.15] +synonym: "4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)" EXACT [EC:1.14.99.15] +synonym: "p-anisic O-demethylase activity" EXACT [EC:1.14.99.15] +synonym: "piperonylate-4-O-demethylase activity" EXACT [EC:1.14.99.15] +xref: EC:1.14.99.15 +xref: KEGG_REACTION:R01306 +xref: MetaCyc:1.14.99.15-RXN +xref: RHEA:18613 +xref: UM-BBD_reactionID:r0154 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0018693 +name: ethylbenzene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2)." [EC:1.17.99.2, RHEA:17897] +synonym: "ethylbenzene dehydrogenase activity" EXACT [EC:1.17.99.2] +synonym: "ethylbenzene:(acceptor) oxidoreductase activity" EXACT [EC:1.17.99.2] +xref: EC:1.17.99.2 +xref: KEGG_REACTION:R05745 +xref: MetaCyc:RXN-1301 +xref: RHEA:17897 +xref: UM-BBD_reactionID:r0234 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0018694 +name: p-cymene methyl hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol." [UM-BBD_reactionID:r0392] +xref: EC:1.17.99 +xref: MetaCyc:RXN-661 +xref: UM-BBD_reactionID:r0392 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0018695 +name: 4-cresol dehydrogenase (hydroxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor." [EC:1.17.9.1] +synonym: "4-cresol dehydrogenase activity" EXACT [] +synonym: "4-cresol:acceptor oxidoreductase (methyl-hydroxylating)" EXACT [EC:1.17.9.1] +synonym: "p-cresol methylhydroxylase activity" EXACT [EC:1.17.9.1] +synonym: "p-cresol-(acceptor) oxidoreductase (hydroxylating) activity" EXACT [EC:1.17.9.1] +xref: EC:1.17.9.1 +xref: MetaCyc:1.17.99.1-RXN +xref: RHEA:15141 +xref: UM-BBD_reactionID:r0272 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0018697 +name: carbonyl sulfide nitrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide." [UM-BBD_reactionID:r0600] +synonym: "carbonyl sulphide nitrogenase activity" EXACT [] +xref: EC:1.18.6.1 +xref: UM-BBD_reactionID:r0600 +is_a: GO:0016732 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor + +[Term] +id: GO:0018698 +name: vinyl chloride reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene." [UM-BBD_reactionID:r0352] +xref: EC:1.97.1 +xref: MetaCyc:VCREDCHLOR-RXN +xref: UM-BBD_reactionID:r0352 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018699 +name: 1,1,1-trichloroethane reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl." [UM-BBD_reactionID:r1007] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r1007 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018700 +name: 2-chloro-N-isopropylacetanilide reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide." [UM-BBD_reactionID:r0719] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0719 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018701 +name: 2,5-dichlorohydroquinone reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone)." [UM-BBD_enzymeID:e0366] +xref: EC:1.97.1 +xref: UM-BBD_enzymeID:e0366 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018702 +name: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU." [UM-BBD_reactionID:r0440] +synonym: "1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity" EXACT [] +synonym: "DDE dehalogenase activity" EXACT [] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0440 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018703 +name: 2,4-dichlorophenoxyacetate dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate." [UM-BBD_reactionID:r0280] +xref: UM-BBD_reactionID:r0280 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018704 +name: obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde." [UM-BBD_enzymeID:e0237] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0018705 +name: 1,2-dichloroethene reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride." [UM-BBD_enzymeID:e0272] +synonym: "1,2-dichloroethylene reductive dehalogenase activity" EXACT [] +xref: UM-BBD_enzymeID:e0272 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018706 +name: pyrogallol hydroxytransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene." [EC:1.97.1.2] +synonym: "1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity" EXACT [EC:1.97.1.2] +synonym: "1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)" EXACT [EC:1.97.1.2] +synonym: "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity" EXACT [EC:1.97.1.2] +synonym: "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity" EXACT [EC:1.97.1.2] +synonym: "1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity" EXACT [EC:1.97.1.2] +synonym: "pyrogallol hydroxyltransferase activity" EXACT [] +synonym: "transhydroxylase activity" RELATED [EC:1.97.1.2] +xref: EC:1.97.1.2 +xref: MetaCyc:1.97.1.2-RXN +xref: UM-BBD_reactionID:r0006 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0018707 +name: 1-phenanthrol methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene." [UM-BBD_reactionID:r0493] +xref: UM-BBD_reactionID:r0493 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0018708 +name: thiol S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether." [EC:2.1.1.9] +synonym: "S-adenosyl-L-methionine:thiol S-methyltransferase activity" EXACT [EC:2.1.1.9] +synonym: "thiol methyltransferase activity" EXACT [EC:2.1.1.9] +synonym: "TMT" RELATED [EC:2.1.1.9] +xref: EC:2.1.1.9 +xref: MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-175976 "TMT transfers CH3 from AdoMet to BME" +xref: UM-BBD_enzymeID:e0146 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0018710 +name: acetone carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate." [EC:6.4.1.6, RHEA:18385] +synonym: "acetone:carbon-dioxide ligase (AMP-forming)" EXACT [EC:6.4.1.6] +xref: EC:6.4.1.6 +xref: KEGG_REACTION:R05735 +xref: MetaCyc:6.4.1.6-RXN +xref: RHEA:18385 +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0018711 +name: benzoyl acetate-CoA thiolase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA." [UM-BBD_reactionID:r0243] +xref: MetaCyc:RXN-1305 +xref: UM-BBD_reactionID:r0243 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0018712 +name: 3-hydroxybutyryl-CoA thiolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA." [UM-BBD_reactionID:r0010] +xref: MetaCyc:R7-RXN +xref: UM-BBD_reactionID:r0010 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0018713 +name: 3-ketopimelyl-CoA thiolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA." [UM-BBD_reactionID:r0197] +xref: MetaCyc:RXN-8032 +xref: UM-BBD_reactionID:r0197 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0018715 +name: 9-phenanthrol UDP-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP." [UM-BBD_reactionID:r0567] +xref: UM-BBD_reactionID:r0567 +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0018716 +name: 1-phenanthrol glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O." [UM-BBD_reactionID:r0525] +xref: UM-BBD_reactionID:r0525 +is_a: GO:0019112 ! phenanthrol glycosyltransferase activity + +[Term] +id: GO:0018717 +name: 9-phenanthrol glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O." [UM-BBD_reactionID:r0511] +xref: UM-BBD_reactionID:r0511 +is_a: GO:0019112 ! phenanthrol glycosyltransferase activity + +[Term] +id: GO:0018718 +name: 1,2-dihydroxy-phenanthrene glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP." [UM-BBD_reactionID:r0569] +xref: UM-BBD_reactionID:r0569 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0018719 +name: 6-aminohexanoate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate." [UM-BBD_reactionID:r0449] +xref: MetaCyc:R562-RXN +xref: UM-BBD_reactionID:r0449 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0018720 +name: phenol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate." [UM-BBD_reactionID:r0155] +xref: MetaCyc:PHENOLPHOS-RXN +xref: UM-BBD_reactionID:r0155 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0018721 +name: trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate." [UM-BBD_reactionID:r0559] +synonym: "trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0559 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0018722 +name: 1-phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate." [UM-BBD_reactionID:r0565] +synonym: "1-phenanthrol sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0565 +is_a: GO:0019111 ! phenanthrol sulfotransferase activity + +[Term] +id: GO:0018723 +name: 3-phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate." [UM-BBD_reactionID:r0561] +synonym: "3-phenanthrol sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0561 +is_a: GO:0019111 ! phenanthrol sulfotransferase activity + +[Term] +id: GO:0018724 +name: 4-phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate." [UM-BBD_reactionID:r0562] +synonym: "4-phenanthrol sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0562 +is_a: GO:0019111 ! phenanthrol sulfotransferase activity + +[Term] +id: GO:0018725 +name: trans-3,4-dihydrodiolphenanthrene sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate." [UM-BBD_reactionID:r0558] +synonym: "trans-3,4-dihydrodiolphenanthrene sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0558 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0018726 +name: 9-phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate." [UM-BBD_reactionID:r0564] +synonym: "9-phenanthrol sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0564 +is_a: GO:0019111 ! phenanthrol sulfotransferase activity + +[Term] +id: GO:0018727 +name: 2-phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate." [UM-BBD_reactionID:r0563] +synonym: "2-phenanthrol sulphotransferase activity" EXACT [] +xref: UM-BBD_reactionID:r0563 +is_a: GO:0019111 ! phenanthrol sulfotransferase activity + +[Term] +id: GO:0018729 +name: propionate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA." [EC:2.8.3.1] +synonym: "acetyl-CoA:propanoate CoA-transferase activity" EXACT [EC:2.8.3.1] +synonym: "propionate coenzyme A-transferase activity" EXACT [EC:2.8.3.1] +synonym: "propionate-CoA:lactoyl-CoA transferase activity" EXACT [EC:2.8.3.1] +synonym: "propionyl CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.1] +synonym: "propionyl-CoA transferase activity" EXACT [EC:2.8.3.1] +xref: EC:2.8.3.1 +xref: MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN +xref: RHEA:23520 +xref: UM-BBD_reactionID:r0087 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0018730 +name: glutaconate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA." [EC:2.8.3.12] +synonym: "acetyl-CoA:(E)-glutaconate CoA-transferase activity" EXACT [EC:2.8.3.12] +xref: EC:2.8.3.12 +xref: MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN +xref: RHEA:23208 +xref: UM-BBD_reactionID:r0085 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0018731 +name: 1-oxa-2-oxocycloheptane lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate." [UM-BBD_reactionID:r0167] +xref: UM-BBD_reactionID:r0167 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0018732 +name: sulfolactone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate." [UM-BBD_reactionID:r0583] +synonym: "sulpholactone hydrolase activity" EXACT [] +xref: EC:3.1.1.92 +xref: UM-BBD_reactionID:r0583 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0018733 +name: 3,4-dihydrocoumarin hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate." [UM-BBD_reactionID:r0419] +xref: EC:3.1.1.35 +xref: UM-BBD_reactionID:r0419 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0018734 +name: butyrolactone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate." [UM-BBD_reactionID:r0016] +xref: UM-BBD_reactionID:r0016 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0018736 +name: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA." [UM-BBD_reactionID:r0206] +xref: UM-BBD_reactionID:r0206 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018737 +name: 2-ketocyclohexane-1-carboxyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA." [UM-BBD_reactionID:r0193] +xref: UM-BBD_reactionID:r0193 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018738 +name: S-formylglutathione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+)." [EC:3.1.2.12, RHEA:14961] +subset: goslim_chembl +xref: EC:3.1.2.12 +xref: KEGG_REACTION:R00527 +xref: MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN +xref: Reactome:R-HSA-5693724 "ESD dimer hydrolyses S-FGSH to GSH" +xref: RHEA:14961 +xref: UM-BBD_reactionID:r0241 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0018739 +name: 4-hydroxybenzoyl-CoA thioesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+)." [EC:3.1.2.23, RHEA:11948] +synonym: "4-hydroxybenzoyl-CoA hydrolase activity" EXACT [EC:3.1.2.23] +synonym: "4-hydroxybenzoyl-CoA thiolesterase activity" EXACT [] +xref: EC:3.1.2.23 +xref: KEGG_REACTION:R01301 +xref: MetaCyc:3.1.2.23-RXN +xref: RHEA:11948 +xref: UM-BBD_reactionID:r0141 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0018740 +name: 2'-hydroxybiphenyl-2-sulfinate desulfinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite." [EC:3.13.1.3, RHEA:12945] +synonym: "2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity" EXACT [] +synonym: "2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity" EXACT [EC:3.13.1.3] +synonym: "2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity" EXACT [] +synonym: "dibenzothiophene desulfurization enzyme B" RELATED [EC:3.13.1.3] +synonym: "DszB" RELATED [EC:3.13.1.3] +synonym: "gene dszB-encoded hydrolase activity" EXACT [EC:3.13.1.3] +synonym: "HBPSi desulfinase activity" EXACT [EC:3.13.1.3] +synonym: "HPBS desulfinase activity" EXACT [EC:3.13.1.3] +xref: EC:3.13.1.3 +xref: KEGG_REACTION:R07311 +xref: MetaCyc:RXN-624 +xref: RHEA:12945 +xref: UM-BBD_enzymeID:e0216 +is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds + +[Term] +id: GO:0018741 +name: alkyl sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol." [UM-BBD_reactionID:r0602] +synonym: "alkyl sulphatase activity" EXACT [] +xref: EC:3.1.6 +xref: UM-BBD_reactionID:r0602 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0018742 +name: epoxide hydrolase B activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers." [UM-BBD_enzymeID:e0051] +xref: EC:3.3.2 +xref: UM-BBD_enzymeID:e0051 +is_a: GO:0004301 ! epoxide hydrolase activity + +[Term] +id: GO:0018743 +name: phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene." [UM-BBD_reactionID:r0560] +xref: EC:3.3.2 +xref: UM-BBD_reactionID:r0560 +is_a: GO:0019119 ! phenanthrene-9,10-epoxide hydrolase activity + +[Term] +id: GO:0018744 +name: limonene-1,2-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide." [EC:3.3.2.8] +synonym: "limonene oxide hydrolase activity" EXACT [EC:3.3.2.8] +xref: EC:3.3.2.8 +xref: MetaCyc:3.3.2.8-RXN +xref: RHEA:10700 +xref: UM-BBD_reactionID:r0734 +is_a: GO:0004301 ! epoxide hydrolase activity + +[Term] +id: GO:0018745 +name: epoxide hydrolase A activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol." [UM-BBD_enzymeID:e0049] +xref: EC:3.3.2 +xref: UM-BBD_enzymeID:e0049 +is_a: GO:0004301 ! epoxide hydrolase activity + +[Term] +id: GO:0018746 +name: phenanthrene-3,4-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene." [UM-BBD_reactionID:r0535] +xref: UM-BBD_reactionID:r0535 +is_a: GO:0019118 ! phenanthrene-epoxide hydrolase activity + +[Term] +id: GO:0018747 +name: phenanthrene-1,2-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene." [UM-BBD_reactionID:r0536] +xref: UM-BBD_reactionID:r0536 +is_a: GO:0019118 ! phenanthrene-epoxide hydrolase activity + +[Term] +id: GO:0018748 +name: iprodione amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate." [UM-BBD_reactionID:r0706] +xref: UM-BBD_reactionID:r0706 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0018749 +name: (3,5-dichlorophenylurea)acetate amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine." [UM-BBD_reactionID:r0708] +xref: UM-BBD_reactionID:r0708 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0018750 +name: biuret amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3." [EC:3.5.1.84] +xref: EC:3.5.1.84 +xref: RHEA:17525 +xref: UM-BBD_reactionID:r0846 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0018751 +name: 3,5-dichlorophenylcarboximide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate." [UM-BBD_reactionID:r0707] +xref: UM-BBD_reactionID:r0707 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0018752 +name: epsilon-caprolactam lactamase activity +namespace: molecular_function +def: "Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate." [UM-BBD_reactionID:r0448] +xref: MetaCyc:R561-RXN +xref: UM-BBD_reactionID:r0448 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0018753 +name: cyanuric acid amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2." [EC:3.5.2.15] +xref: EC:3.5.2.15 +xref: MetaCyc:R468-RXN +xref: RHEA:14641 +xref: UM-BBD_reactionID:r0116 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0018754 +name: ammelide aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3." [PMID:1991731] +xref: MetaCyc:RXN-8017 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0018755 +name: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-." [UM-BBD_reactionID:r1414] +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0018756 +name: ammeline aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ammeline + H2O = ammelide + NH3." [PMID:1991731] +xref: MetaCyc:RXN-8016 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0018757 +name: deisopropylhydroxyatrazine aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine." [UM-BBD_reactionID:r0121] +xref: KEGG_REACTION:R05574 +xref: UM-BBD_reactionID:r0121 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0018758 +name: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid." [UM-BBD_reactionID:r0122] +xref: UM-BBD_reactionID:r0122 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0018759 +name: methenyltetrahydromethanopterin cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+)." [EC:3.5.4.27, RHEA:19053] +synonym: "5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)" EXACT [EC:3.5.4.27] +synonym: "5,10-methenyltetrahydromethanopterin cyclohydrolase activity" EXACT [EC:3.5.4.27] +synonym: "methenyl-H(4)MPT cyclohydrolase activity" EXACT [EC:3.5.4.27] +synonym: "methenyl-H4MPT cyclohydrolase activity" EXACT [EC:3.5.4.27] +synonym: "N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity" EXACT [EC:3.5.4.27] +xref: EC:3.5.4.27 +xref: KEGG_REACTION:R03464 +xref: MetaCyc:3.5.4.27-RXN +xref: RHEA:19053 +xref: UM-BBD_reactionID:r0347 +is_a: GO:0019238 ! cyclohydrolase activity + +[Term] +id: GO:0018760 +name: thiocyanate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+)." [EC:3.5.5.8, RHEA:21464] +synonym: "thiocyanate aminohydrolase activity" EXACT [EC:3.5.5.8] +xref: EC:3.5.5.8 +xref: KEGG_REACTION:R05780 +xref: MetaCyc:RXN-1761 +xref: RHEA:21464 +xref: UM-BBD_reactionID:r0598 +is_a: GO:0016815 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles + +[Term] +id: GO:0018761 +name: bromoxynil nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil." [EC:3.5.5.6, RHEA:22100] +synonym: "3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity" EXACT [] +synonym: "bromoxynil-specific nitrilase activity" EXACT [] +xref: EC:3.5.5.6 +xref: KEGG_REACTION:R04349 +xref: MetaCyc:3.5.5.6-RXN +xref: RHEA:22100 +xref: UM-BBD_enzymeID:e0357 +is_a: GO:0000257 ! nitrilase activity + +[Term] +id: GO:0018762 +name: aliphatic nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: R-CN + H2O = R-COOH + NH3." [EC:3.5.5.7] +synonym: "aliphatic nitrile aminohydrolase activity" EXACT [EC:3.5.5.7] +xref: EC:3.5.5.7 +xref: MetaCyc:3.5.5.7-RXN +xref: UM-BBD_reactionID:r0622 +is_a: GO:0000257 ! nitrilase activity + +[Term] +id: GO:0018763 +name: hydroxydechloroatrazine ethylaminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine." [EC:3.5.4.43] +synonym: "4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity" EXACT [EC:3.5.4.43] +synonym: "AtzB" RELATED [] +synonym: "hydroxyatrazine ethylaminohydrolase activity" EXACT [] +synonym: "hydroxyatrazine hydrolase activity" EXACT [EC:3.5.4.43] +xref: EC:3.5.4.43 +xref: MetaCyc:R122-RXN +xref: RHEA:23092 +xref: UM-BBD_enzymeID:e0085 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0018764 +name: N-isopropylammelide isopropylaminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine." [EC:3.5.4.42] +synonym: "AtzC" RELATED [] +xref: EC:3.5.4.42 +xref: MetaCyc:R123-RXN +xref: RHEA:23608 +xref: UM-BBD_enzymeID:e0086 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0018765 +name: 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate." [UM-BBD_reactionID:r0263] +xref: MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN +xref: UM-BBD_reactionID:r0263 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018766 +name: dihydrophloroglucinol hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate." [UM-BBD_reactionID:r0008] +xref: KEGG_REACTION:R07831 +xref: MetaCyc:R6-RXN +xref: UM-BBD_reactionID:r0008 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018767 +name: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate." [UM-BBD_reactionID:r0399] +xref: UM-BBD_reactionID:r0399 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018768 +name: 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate." [UM-BBD_reactionID:r0458] +xref: EC:3.7.1.13 +xref: UM-BBD_reactionID:r0458 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018769 +name: 2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate." [UM-BBD_reactionID:r0311] +xref: UM-BBD_reactionID:r0311 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018770 +name: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+." [UM-BBD_reactionID:r0444] +xref: UM-BBD_reactionID:r0444 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018771 +name: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity +namespace: molecular_function +alt_id: GO:0008680 +def: "Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate." [RHEA:24789] +synonym: "(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity" EXACT systematic_synonym [EC:3.7.1.14] +synonym: "2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity" EXACT [UM-BBD_reactionID:r0438] +xref: EC:3.7.1.14 +xref: MetaCyc:MHPCHYDROL-RXN +xref: RHEA:24789 +xref: UM-BBD_reactionID:r0438 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018772 +name: trioxoheptanoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate." [MetaCyc:R306-RXN, UM-BBD_reactionID:r0094] +xref: MetaCyc:R306-RXN +xref: UM-BBD_reactionID:r0094 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018773 +name: acetylpyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate." [EC:3.7.1.6, RHEA:16097] +synonym: "2,4-dioxopentanoate acetylhydrolase activity" EXACT [EC:3.7.1.6] +xref: EC:3.7.1.6 +xref: KEGG_REACTION:R00324 +xref: MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN +xref: RHEA:16097 +xref: UM-BBD_reactionID:r0095 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018774 +name: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate." [EC:3.7.1.8] +synonym: "2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity" EXACT [EC:3.7.1.8] +synonym: "2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity" EXACT [] +synonym: "HOHPDA hydrolase activity" EXACT [EC:3.7.1.8] +xref: EC:3.7.1.8 +xref: MetaCyc:3.7.1.8-RXN +xref: RHEA:17161 +xref: UM-BBD_enzymeID:e0033 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018775 +name: 2-hydroxymuconate-semialdehyde hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate." [EC:3.7.1.9] +synonym: "2-hydroxymuconate-semialdehyde formylhydrolase activity" EXACT [EC:3.7.1.9] +synonym: "2-hydroxymuconic semialdehyde hydrolase activity" EXACT [EC:3.7.1.9] +synonym: "HMSH" RELATED [EC:3.7.1.9] +synonym: "HOD hydrolase activity" EXACT [EC:3.7.1.9] +xref: EC:3.7.1.9 +xref: MetaCyc:3.7.1.9-RXN +xref: RHEA:14549 +xref: UM-BBD_enzymeID:e0139 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0018776 +name: trans-chloroacrylic acid dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde." [UM-BBD_reactionID:r0689] +xref: UM-BBD_reactionID:r0689 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018777 +name: 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol)." [PMID:10464214] +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018778 +name: DL-2 haloacid dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate." [UM-BBD_reactionID:r0382] +xref: EC:3.8.1.10 +xref: MetaCyc:RXN-9150 +xref: UM-BBD_reactionID:r0382 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018779 +name: obsolete 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0018780 +name: dichloroacetate halidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate." [UM-BBD_reactionID:r0383] +xref: UM-BBD_reactionID:r0383 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018781 +name: S-triazine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine." [UM-BBD_ruleID:bt0330] +xref: UM-BBD_enzymeID:e0091 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018782 +name: cis-chloroacrylic acid dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde." [UM-BBD_reactionID:r0688] +xref: UM-BBD_reactionID:r0688 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018783 +name: deisopropyldeethylatrazine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3." [UM-BBD_reactionID:0129] +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018784 +name: (S)-2-haloacid dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide." [EC:3.8.1.2] +synonym: "(S)-2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.2] +synonym: "2-haloacid dehalogenase activity" EXACT [] +synonym: "2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.2] +synonym: "2-haloalkanoic acid dehalogenase activity" EXACT [EC:3.8.1.2] +synonym: "2-haloalkanoid acid halidohydrolase activity" EXACT [EC:3.8.1.2] +synonym: "2-halocarboxylic acid dehalogenase II activity" EXACT [EC:3.8.1.2] +synonym: "DL-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.2] +synonym: "halocarboxylic acid halidohydrolase activity" EXACT [EC:3.8.1.2] +synonym: "L-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.2] +synonym: "L-DEX activity" EXACT [EC:3.8.1.2] +xref: EC:3.8.1.2 +xref: MetaCyc:2-HALOACID-DEHALOGENASE-RXN +xref: UM-BBD_reactionID:r0090 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018785 +name: haloacetate dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: haloacetate + H2O = glycolate + halide." [EC:3.8.1.3] +synonym: "haloacetate halidohydrolase activity" EXACT [EC:3.8.1.3] +synonym: "monohaloacetate dehalogenase activity" EXACT [EC:3.8.1.3] +xref: EC:3.8.1.3 +xref: MetaCyc:HALOACETATE-DEHALOGENASE-RXN +xref: UM-BBD_enzymeID:e0006 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018786 +name: haloalkane dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide." [EC:3.8.1.5] +synonym: "1-chlorohexane halidohydrolase activity" EXACT [EC:3.8.1.5] +synonym: "1-haloalkane dehalogenase activity" EXACT [EC:3.8.1.5] +synonym: "1-haloalkane halidohydrolase activity" EXACT [EC:3.8.1.5] +xref: EC:3.8.1.5 +xref: MetaCyc:HALOALKANE-DEHALOGENASE-RXN +xref: RHEA:25185 +xref: UM-BBD_enzymeID:e0003 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018787 +name: 4-chlorobenzoyl-CoA dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride." [EC:3.8.1.7] +synonym: "4-chlorobenzoyl CoA chlorohydrolase activity" EXACT [EC:3.8.1.7] +xref: EC:3.8.1.7 +xref: MetaCyc:3.8.1.7-RXN +xref: RHEA:14853 +xref: UM-BBD_enzymeID:e0113 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018788 +name: atrazine chlorohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+)." [EC:3.8.1.8, RHEA:11312] +synonym: "AtzA" RELATED [EC:3.8.1.8] +xref: EC:3.8.1.8 +xref: KEGG_REACTION:R05558 +xref: MetaCyc:3.8.1.8-RXN +xref: RHEA:11312 +xref: UM-BBD_reactionID:r0113 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0018789 +name: cyclamate sulfohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate." [EC:3.10.1.2, RHEA:18481] +synonym: "cyclamate sulfamatase activity" EXACT [] +synonym: "cyclamate sulfamidase activity" EXACT [EC:3.10.1.2] +synonym: "cyclamate sulphohydrolase activity" EXACT [] +synonym: "cyclohexylsulfamate sulfamidase activity" EXACT [EC:3.10.1.2] +synonym: "cyclohexylsulfamate sulfohydrolase activity" EXACT [EC:3.10.1.2] +xref: EC:3.10.1.2 +xref: KEGG_REACTION:R02564 +xref: MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN +xref: RHEA:18481 +xref: UM-BBD_reactionID:r0755 +is_a: GO:0016826 ! hydrolase activity, acting on acid sulfur-nitrogen bonds + +[Term] +id: GO:0018791 +name: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate." [UM-BBD_reactionID:r0398] +xref: UM-BBD_reactionID:r0398 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018792 +name: bis(4-chlorophenyl)acetate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM." [UM-BBD_reactionID:r0520] +synonym: "DDA decarboxylase activity" EXACT [] +xref: UM-BBD_reactionID:r0520 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018793 +name: 3,5-dibromo-4-hydroxybenzoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol." [UM-BBD_reactionID:r0546] +xref: UM-BBD_reactionID:r0546 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018794 +name: 2-hydroxyisobutyrate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol." [UM-BBD_reactionID:r0617] +xref: UM-BBD_reactionID:r0617 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018795 +name: 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate." [UM-BBD_reactionID:r0621] +xref: UM-BBD_reactionID:r0621 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018796 +name: 4,5-dihydroxyphthalate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2." [EC:4.1.1.55] +synonym: "4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)" EXACT [EC:4.1.1.55] +synonym: "4,5-dihydroxyphthalate carboxy-lyase activity" EXACT [EC:4.1.1.55] +xref: EC:4.1.1.55 +xref: MetaCyc:45-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN +xref: RHEA:24184 +xref: UM-BBD_enzymeID:e0106 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018798 +name: gallate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol." [EC:4.1.1.59, RHEA:12749] +synonym: "gallate carboxy-lyase (pyrogallol-forming)" EXACT [EC:4.1.1.59] +synonym: "gallate carboxy-lyase activity" EXACT [EC:4.1.1.59] +synonym: "gallic acid decarboxylase activity" EXACT [] +xref: EC:4.1.1.59 +xref: KEGG_REACTION:R03247 +xref: MetaCyc:GALLATE-DECARBOXYLASE-RXN +xref: RHEA:12749 +xref: UM-BBD_reactionID:r0005 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018799 +name: 4-hydroxybenzoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol." [EC:4.1.1.61, RHEA:10876] +synonym: "4-hydroxybenzoate carboxy-lyase (phenol-forming)" EXACT [EC:4.1.1.61] +synonym: "4-hydroxybenzoate carboxy-lyase activity" EXACT [EC:4.1.1.61] +synonym: "p-hydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.61] +xref: EC:4.1.1.61 +xref: KEGG_REACTION:R01238 +xref: MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN +xref: RHEA:10876 +xref: UM-BBD_reactionID:r0159 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018800 +name: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2." [EC:4.1.1.68] +synonym: "5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity" EXACT [EC:4.1.1.68] +synonym: "5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity" EXACT [] +synonym: "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)" EXACT [EC:4.1.1.68] +synonym: "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.68] +synonym: "HpaG-2" RELATED [] +synonym: "HpaG2" RELATED [] +synonym: "OPET decarboxylase activity" EXACT [] +xref: EC:4.1.1.68 +xref: MetaCyc:4.1.1.68-RXN +xref: RHEA:14397 +xref: UM-BBD_reactionID:r0367 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018801 +name: glutaconyl-CoA decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2)." [EC:7.2.4.5, RHEA:23972] +synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)" EXACT [] +synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase activity" EXACT [EC:7.2.4.5] +synonym: "glutaconyl coenzyme A decarboxylase activity" EXACT [EC:7.2.4.5] +synonym: "pent-2-enoyl-CoA carboxy-lyase activity" EXACT [EC:7.2.4.5] +xref: EC:7.2.4.5 +xref: KEGG_REACTION:R03028 +xref: MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN +xref: RHEA:23972 +xref: UM-BBD_reactionID:r0199 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018802 +name: 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde." [UM-BBD_reactionID:r0370] +xref: EC:4.1.2 +xref: UM-BBD_reactionID:r0370 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018803 +name: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate." [EC:4.1.2.34] +synonym: "(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34] +synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.34] +synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34] +synonym: "2'-carboxybenzalpyruvate aldolase activity" EXACT [EC:4.1.2.34] +synonym: "trans-2'-carboxybenzalpyruvate hydratase-aldolase activity" EXACT [] +xref: EC:4.1.2.34 +xref: MetaCyc:4.1.2.34-RXN +xref: RHEA:16453 +xref: UM-BBD_reactionID:r0487 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0018805 +name: benzylsuccinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate." [EC:4.1.99.11, RHEA:10416] +synonym: "benzylsuccinate fumarate-lyase (toluene-forming)" EXACT [EC:4.1.99.11] +synonym: "benzylsuccinate fumarate-lyase activity" EXACT [EC:4.1.99.11] +xref: EC:4.1.99.11 +xref: KEGG_REACTION:R05598 +xref: MetaCyc:RXN-863 +xref: RHEA:10416 +xref: UM-BBD_enzymeID:e0259 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0018807 +name: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA." [UM-BBD_reactionID:r0204] +xref: EC:3.7.1.21 +xref: RHEA:39651 +xref: UM-BBD_reactionID:r0204 +is_a: GO:0016822 ! hydrolase activity, acting on acid carbon-carbon bonds + +[Term] +id: GO:0018808 +name: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde." [UM-BBD_reactionID:r0484] +xref: UM-BBD_reactionID:r0484 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018809 +name: E-phenylitaconyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA." [UM-BBD_reactionID:r0331] +xref: UM-BBD_reactionID:r0331 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018810 +name: trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene." [UM-BBD_reactionID:r0164] +xref: UM-BBD_reactionID:r0164 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018811 +name: cyclohex-1-ene-1-carboxyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA." [MetaCyc:R266-RXN, UM-BBD_reactionID:r0191] +xref: MetaCyc:R266-RXN +xref: UM-BBD_reactionID:r0191 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018812 +name: 3-hydroxyacyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA)." [UM-BBD_ruleID:bt0291] +xref: Reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA" +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018813 +name: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde)." [UM-BBD_enzymeID:e0257] +xref: EC:4.1.2.45 +xref: RHEA:27389 +xref: UM-BBD_enzymeID:e0257 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018814 +name: phenylacetaldoxime dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile." [EC:4.99.1.7, RHEA:20069] +synonym: "(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity" EXACT [EC:4.99.1.7] +synonym: "(Z)-phenylacetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.7] +synonym: "arylacetaldoxime dehydratase activity" EXACT [EC:4.99.1.7] +synonym: "OxdB" RELATED [EC:4.99.1.7] +synonym: "PAOx dehydratase activity" EXACT [EC:4.99.1.7] +xref: EC:4.99.1.7 +xref: KEGG_REACTION:R07638 +xref: MetaCyc:4.99.1.7-RXN +xref: RHEA:20069 +xref: UM-BBD_reactionID:r0697 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0018815 +name: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine." [MetaCyc:RXN-645, UM-BBD_reactionID:r0051] +xref: MetaCyc:RXN-645 +xref: UM-BBD_reactionID:r0051 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018816 +name: 2-hydroxyisobutyrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate." [UM-BBD_reactionID:r0618] +xref: UM-BBD_reactionID:r0618 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018817 +name: 2-oxo-hept-3-ene-1,7-dioate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate." [UM-BBD_reactionID:r0369] +synonym: "2-oxo-hepta-3-ene-1,7-dioate hydratase activity" EXACT [] +synonym: "2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity" EXACT [] +synonym: "HpaH" RELATED [] +xref: MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN +xref: UM-BBD_reactionID:r0369 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018818 +name: acetylene hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetaldehyde = acetylene + H(2)O." [EC:4.2.1.112, RHEA:17885] +synonym: "acetaldehyde hydro-lyase activity" EXACT [EC:4.2.1.112] +synonym: "AH" RELATED [EC:4.2.1.112] +synonym: "AHy" RELATED [EC:4.2.1.112] +xref: EC:4.2.1.112 +xref: KEGG_REACTION:R05380 +xref: MetaCyc:R141-RXN +xref: RHEA:17885 +xref: UM-BBD_reactionID:r0591 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018819 +name: lactoyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O." [EC:4.2.1.54] +synonym: "acrylyl coenzyme A hydratase activity" EXACT [EC:4.2.1.54] +synonym: "lactoyl coenzyme A dehydratase activity" EXACT [EC:4.2.1.54] +synonym: "lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)" EXACT [EC:4.2.1.54] +synonym: "lactoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.54] +synonym: "lactyl CoA dehydratase activity" EXACT [EC:4.2.1.54] +synonym: "lactyl-coenzyme A dehydrase activity" EXACT [EC:4.2.1.54] +xref: EC:4.2.1.54 +xref: MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN +xref: MetaCyc:RXN-781 +xref: RHEA:21056 +xref: UM-BBD_reactionID:r0086 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018820 +name: cyanamide hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: urea = cyanamide + H(2)O." [EC:4.2.1.69, RHEA:23056] +synonym: "urea hydro-lyase (cyanamide-forming)" EXACT [EC:4.2.1.69] +synonym: "urea hydro-lyase activity" EXACT [EC:4.2.1.69] +xref: EC:4.2.1.69 +xref: KEGG_REACTION:R00778 +xref: MetaCyc:CYANAMIDE-HYDRATASE-RXN +xref: RHEA:23056 +xref: UM-BBD_reactionID:r0668 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018822 +name: nitrile hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aliphatic amide = a nitrile + H2O." [EC:4.2.1.84] +synonym: "3-cyanopyridine hydratase activity" EXACT [EC:4.2.1.84] +synonym: "acrylonitrile hydratase activity" EXACT [EC:4.2.1.84] +synonym: "aliphatic nitrile hydratase activity" EXACT [EC:4.2.1.84] +synonym: "aliphatic-amide hydro-lyase (nitrile-forming)" EXACT [EC:4.2.1.84] +synonym: "H-NHase activity" EXACT [EC:4.2.1.84] +synonym: "L-NHase activity" EXACT [EC:4.2.1.84] +synonym: "NHase activity" EXACT [EC:4.2.1.84] +synonym: "nitrile hydro-lyase activity" EXACT [EC:4.2.1.84] +xref: EC:4.2.1.84 +xref: MetaCyc:NITRILE-HYDRATASE-RXN +xref: RHEA:12673 +xref: UM-BBD_enzymeID:e0067 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018823 +name: cyclohexa-1,5-dienecarbonyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA." [EC:4.2.1.100, RHEA:21856] +synonym: "6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)" RELATED [EC:4.2.1.100] +synonym: "cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity" EXACT [] +synonym: "cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity" EXACT [EC:4.2.1.100] +synonym: "cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity" EXACT [EC:4.2.1.100] +synonym: "cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.100] +synonym: "dienoyl-CoA hydratase activity" EXACT [EC:4.2.1.100] +xref: EC:4.2.1.100 +xref: KEGG_REACTION:R05597 +xref: MetaCyc:4.2.1.100-RXN +xref: RHEA:21856 +xref: UM-BBD_reactionID:r0203 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0018824 +name: (hydroxyamino)benzene mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol." [EC:5.4.4.1, UM-BBD_reactionID:r0304] +synonym: "(hydroxyamino)benzene hydroxymutase activity" EXACT [EC:5.4.4.1] +synonym: "HAB mutase activity" EXACT [EC:5.4.4.1] +synonym: "hydroxylaminobenzene hydroxymutase activity" EXACT [EC:5.4.4.1] +synonym: "hydroxylaminobenzene mutase activity" EXACT [EC:5.4.4.1] +xref: MetaCyc:5.4.4.1-RXN +xref: UM-BBD_reactionID:r0304 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0018825 +name: triethanolamine lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde." [UM-BBD_enzymeID:e0421] +xref: UM-BBD_enzymeID:e0421 +is_a: GO:0016843 ! amine-lyase activity + +[Term] +id: GO:0018826 +name: methionine gamma-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate." [EC:4.4.1.11, RHEA:23800] +synonym: "L-methioninase activity" EXACT [EC:4.4.1.11] +synonym: "L-methionine gamma-lyase activity" EXACT [EC:4.4.1.11] +synonym: "L-methionine methanethiol-lyase (deaminating)" EXACT [EC:4.4.1.11] +synonym: "L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.11] +synonym: "methioninase activity" EXACT [EC:4.4.1.11] +synonym: "methionine dethiomethylase activity" EXACT [EC:4.4.1.11] +synonym: "methionine lyase activity" EXACT [EC:4.4.1.11] +xref: EC:4.4.1.11 +xref: MetaCyc:METHIONINE-GAMMA-LYASE-RXN +xref: RHEA:23800 +xref: UM-BBD_reactionID:r0432 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0018827 +name: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU." [UM-BBD_reactionID:r0515] +synonym: "DDMS dehydrochlorinase activity" EXACT [] +xref: EC:4.5.1 +xref: UM-BBD_reactionID:r0515 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018828 +name: halohydrin hydrogen-halide-lyase A activity +namespace: molecular_function +def: "Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane." [UM-BBD_enzymeID:e0048] +xref: UM-BBD_enzymeID:e0048 +is_a: GO:0019181 ! halohydrin hydrogen-halide-lyase activity + +[Term] +id: GO:0018829 +name: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU." [UM-BBD_reactionID:r0513] +synonym: "DDD dehydrochlorinase activity" EXACT [] +xref: EC:4.5.1 +xref: UM-BBD_reactionID:r0513 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018830 +name: gamma-hexachlorocyclohexane dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene." [UM-BBD_enzymeID:e0359] +xref: EC:4.5.1 +xref: UM-BBD_enzymeID:e0359 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018831 +name: 5-chloro-1,2,4-trihydroxybenzene dechlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone." [UM-BBD_reactionID:r0666] +xref: EC:4.5.1 +xref: UM-BBD_reactionID:r0666 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018832 +name: halohydrin hydrogen-halide-lyase B activity +namespace: molecular_function +def: "Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane." [UM-BBD_enzymeID:e0050] +xref: UM-BBD_enzymeID:e0050 +is_a: GO:0019181 ! halohydrin hydrogen-halide-lyase activity + +[Term] +id: GO:0018833 +name: DDT-dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+)." [EC:4.5.1.1, RHEA:19217] +synonym: "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]" RELATED [EC:4.5.1.1] +synonym: "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity" EXACT [EC:4.5.1.1] +synonym: "DDT dehydrochlorinase activity" EXACT [] +synonym: "DDT-as" RELATED [EC:4.5.1.1] +synonym: "DDT-ase activity" EXACT [EC:4.5.1.1] +synonym: "DDTase activity" EXACT [EC:4.5.1.1] +xref: EC:4.5.1.1 +xref: KEGG_REACTION:R04522 +xref: MetaCyc:DDT-DEHYDROCHLORINASE-RXN +xref: RHEA:19217 +xref: UM-BBD_reactionID:r0439 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018834 +name: dichloromethane dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+)." [EC:4.5.1.3, RHEA:15397] +synonym: "dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)" EXACT [EC:4.5.1.3] +synonym: "dichloromethane chloride-lyase (chloride-hydrolysing)" EXACT [EC:4.5.1.3] +xref: EC:4.5.1.3 +xref: KEGG_REACTION:R00603 +xref: MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN +xref: RHEA:15397 +xref: UM-BBD_reactionID:r0188 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0018835 +name: carbon phosphorus lyase activity +namespace: molecular_function +alt_id: GO:0009456 +def: "Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate)." [PMID:3804975] +xref: EC:4.7.1 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0018836 +name: alkylmercury lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+." [EC:4.99.1.2] +synonym: "alkylmercury mercuric-lyase (alkane-forming)" EXACT [EC:4.99.1.2] +synonym: "alkylmercury mercuric-lyase activity" EXACT [EC:4.99.1.2] +synonym: "organomercurial lyase activity" EXACT [EC:4.99.1.2] +synonym: "organomercury lyase activity" EXACT [EC:4.99.1.2] +xref: EC:4.99.1.2 +xref: MetaCyc:ALKYLMERCURY-LYASE-RXN +xref: UM-BBD_enzymeID:e0055 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0018837 +name: 2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate." [UM-BBD_reactionID:r0502] +xref: UM-BBD_reactionID:r0502 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0018838 +name: mandelate racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-mandelate = (R)-mandelate." [EC:5.1.2.2] +xref: EC:5.1.2.2 +xref: MetaCyc:MANDELATE-RACEMASE-RXN +xref: RHEA:13945 +xref: UM-BBD_reactionID:r0091 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0018839 +name: cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate." [UM-BBD_reactionID:r0163] +xref: EC:5.2.1 +xref: UM-BBD_reactionID:r0163 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0018842 +name: 3-carboxymuconate cycloisomerase type II activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone." [UM-BBD_reactionID:r0582] +xref: EC:5.5.1.2 +xref: RHEA:23656 +xref: UM-BBD_reactionID:r0582 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018844 +name: 2-hydroxytetrahydrofuran isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde." [UM-BBD_reactionID:r0019] +xref: EC:5.3.99 +xref: UM-BBD_reactionID:r0019 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0018845 +name: 2-hydroxychromene-2-carboxylate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate." [RHEA:27401] +xref: EC:5.99.1.4 +xref: KEGG_REACTION:R05137 +xref: MetaCyc:RXNN-386 +xref: RHEA:27401 +xref: UM-BBD_reactionID:r0337 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0018846 +name: styrene-oxide isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: styrene oxide = phenylacetaldehyde." [EC:5.3.99.7, RHEA:21604] +synonym: "SOI activity" EXACT [EC:5.3.99.7] +synonym: "styrene oxide isomerase activity" EXACT [] +synonym: "styrene-oxide isomerase (epoxide-cleaving)" EXACT [EC:5.3.99.7] +xref: EC:5.3.99.7 +xref: KEGG_REACTION:R02615 +xref: MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN +xref: RHEA:21604 +xref: UM-BBD_reactionID:r0034 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0018847 +name: alpha-pinene lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-pinene = limonene." [UM-BBD_reactionID:r0712] +xref: EC:5.5.1 +xref: UM-BBD_reactionID:r0712 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018848 +name: pinocarveol isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: pinocarveol = carveol." [UM-BBD_reactionID:r0715] +xref: EC:5.5.1 +xref: UM-BBD_reactionID:r0715 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018849 +name: muconate cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate." [EC:5.5.1.1] +synonym: "2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.1] +synonym: "4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing)" EXACT [EC:5.5.1.1] +synonym: "cis,cis-muconate cycloisomerase activity" EXACT [EC:5.5.1.1] +synonym: "cis,cis-muconate lactonizing enzyme I activity" EXACT [EC:5.5.1.1] +synonym: "cis,cis-muconate-lactonizing enzyme" RELATED [EC:5.5.1.1] +synonym: "muconate cycloisomerase I activity" EXACT [EC:5.5.1.1] +synonym: "muconate lactonizing enzyme activity" EXACT [EC:5.5.1.1] +xref: EC:5.5.1.1 +xref: MetaCyc:MUCONATE-CYCLOISOMERASE-RXN +xref: RHEA:10640 +xref: UM-BBD_enzymeID:e0133 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018850 +name: chloromuconate cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate." [EC:5.5.1.7] +synonym: "2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.7] +synonym: "muconate cycloisomerase II activity" EXACT [EC:5.5.1.7] +xref: EC:5.5.1.7 +xref: RHEA:11032 +xref: UM-BBD_enzymeID:e0065 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018851 +name: alpha-pinene-oxide decyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal." [EC:5.5.1.10, RHEA:16693] +synonym: "alpha-pinene oxide lyase activity" EXACT [] +synonym: "alpha-pinene-oxide lyase (decyclizing)" EXACT [EC:5.5.1.10] +xref: EC:5.5.1.10 +xref: KEGG_REACTION:R04040 +xref: MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN +xref: RHEA:16693 +xref: UM-BBD_reactionID:r0743 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018852 +name: dichloromuconate cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate." [EC:5.5.1.11] +synonym: "2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.11] +xref: EC:5.5.1.11 +xref: MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN +xref: RHEA:17437 +xref: UM-BBD_reactionID:r0277 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0018853 +name: obsolete perillyl-CoA synthetase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA." [UM-BBD_reactionID:r0731] +comment: This term was made obsolete because it represents two reactions. +synonym: "perillyl-CoA synthetase activity" EXACT [] +xref: EC:6.2.1 +xref: UM-BBD_reactionID:r0731 +is_obsolete: true +consider: GO:0052685 +consider: GO:0052686 + +[Term] +id: GO:0018854 +name: 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [UM-BBD_reactionID:r0737] +xref: UM-BBD_reactionID:r0737 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018855 +name: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA." [UM-BBD_reactionID:r0429] +xref: EC:6.2.1.38 +xref: UM-BBD_reactionID:r0429 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018856 +name: benzoyl acetate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA." [UM-BBD_reactionID:r0242] +xref: KEGG_REACTION:R05452 +xref: SABIO-RK:5058 +xref: UM-BBD_reactionID:r0242 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018857 +name: 2,4-dichlorobenzoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA." [UM-BBD_reactionID:r0137] +xref: UM-BBD_reactionID:r0137 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018858 +name: benzoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate + H(+)." [EC:6.2.1.25, RHEA:10132] +synonym: "benzoate-coenzyme A ligase activity" EXACT [EC:6.2.1.25] +synonym: "benzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.25] +synonym: "benzoyl CoA synthetase (AMP forming)" EXACT [EC:6.2.1.25] +synonym: "benzoyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.25] +xref: EC:6.2.1.25 +xref: KEGG_REACTION:R01422 +xref: MetaCyc:BENZOATE--COA-LIGASE-RXN +xref: RHEA:10132 +xref: UM-BBD_reactionID:r0189 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018859 +name: 4-hydroxybenzoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA." [EC:6.2.1.27] +synonym: "4-hydroxybenzoate-CoA synthetase activity" EXACT [EC:6.2.1.27] +synonym: "4-hydroxybenzoate-coenzyme A ligase (AMP-forming)" EXACT [EC:6.2.1.27] +synonym: "4-hydroxybenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.27] +synonym: "4-hydroxybenzoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.27] +synonym: "4-hydroxybenzoyl-CoA ligase activity" EXACT [EC:6.2.1.27] +xref: EC:6.2.1.27 +xref: KEGG_REACTION:R01300 +xref: MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN +xref: RHEA:23116 +xref: UM-BBD_reactionID:r0156 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018860 +name: anthranilate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA." [EC:6.2.1.32] +synonym: "2-aminobenzoate coenzyme A ligase activity" EXACT [EC:6.2.1.32] +synonym: "2-aminobenzoate-CoA ligase activity" EXACT [EC:6.2.1.32] +synonym: "2-aminobenzoate-coenzyme A ligase activity" EXACT [EC:6.2.1.32] +synonym: "anthranilate--CoA ligase activity" EXACT [] +synonym: "anthranilate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.32] +synonym: "anthraniloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.32] +xref: EC:6.2.1.32 +xref: KEGG_REACTION:R00982 +xref: MetaCyc:AMINOBENZCOALIG-RXN +xref: RHEA:10828 +xref: UM-BBD_reactionID:r0341 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018861 +name: 4-chlorobenzoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway." [EC:6.2.1.33] +synonym: "4-chlorobenzoate:CoA ligase activity" EXACT [] +xref: EC:6.2.1.33 +xref: KEGG_REACTION:R03932 +xref: MetaCyc:6.2.1.33-RXN +xref: RHEA:23220 +xref: UM-BBD_reactionID:r0139 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0018862 +name: phenylphosphate carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate." [UM-BBD_reactionID:r0157] +xref: EC:6.4.1 +xref: MetaCyc:PHENYLPCARB-RXN +xref: UM-BBD_reactionID:r0157 +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0018863 +name: phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene." [UM-BBD_reactionID:r0496] +xref: EC:3.3.2 +xref: UM-BBD_reactionID:r0496 +is_a: GO:0019119 ! phenanthrene-9,10-epoxide hydrolase activity + +[Term] +id: GO:0018864 +name: acetylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes." [ISBN:0721662544] +synonym: "acetylene metabolism" EXACT [] +synonym: "ethyne metabolic process" EXACT [] +synonym: "ethyne metabolism" EXACT [] +xref: UM-BBD_pathwayID:atl +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0043452 ! cellular alkyne metabolic process + +[Term] +id: GO:0018865 +name: acrylonitrile metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers." [http://www.iversonsoftware.com/reference/chemistry/a/acrylonitrile.htm] +synonym: "acrylonitrile metabolism" EXACT [] +xref: UM-BBD_pathwayID:acr +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0018866 +name: adamantanone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists." [GOC:ai] +synonym: "adamantanone metabolism" EXACT [] +xref: UM-BBD_pathwayID:ada +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018867 +name: alpha-pinene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor." [UM-BBD_pathwayID:apn] +synonym: "alpha-pinene metabolism" EXACT [] +xref: UM-BBD_pathwayID:apn +is_a: GO:0033073 ! pinene metabolic process + +[Term] +id: GO:0018868 +name: 2-aminobenzenesulfonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [UM-BBD_pathwayID:abs] +synonym: "2-aminobenzenesulfonate metabolism" EXACT [] +synonym: "2-aminobenzenesulphonate metabolic process" EXACT [] +synonym: "2-aminobenzenesulphonate metabolism" EXACT [] +xref: UM-BBD_pathwayID:abs +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018870 +name: anaerobic 2-aminobenzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen." [GOC:ai] +synonym: "anaerobic 2-aminobenzoate metabolism" EXACT [] +xref: UM-BBD_pathwayID:abz +is_a: GO:0018875 ! anaerobic benzoate metabolic process +is_a: GO:0043420 ! anthranilate metabolic process + +[Term] +id: GO:0018871 +name: 1-aminocyclopropane-1-carboxylate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants." [UM-BBD_pathwayID:acp] +synonym: "1-aminocyclopropane-1-carboxylate metabolism" EXACT [] +synonym: "ACP metabolic process" EXACT [] +synonym: "ACP metabolism" EXACT [] +xref: UM-BBD_pathwayID:acp +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0018872 +name: arsonoacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides." [UM-BBD_pathwayID:ara] +synonym: "arsonoacetate metabolism" EXACT [] +xref: UM-BBD_pathwayID:ara +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0018873 +name: atrazine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide." [UM-BBD_pathwayID:atr] +synonym: "atrazine metabolism" EXACT [] +xref: UM-BBD_pathwayID:atr +is_a: GO:0006595 ! polyamine metabolic process +is_a: GO:0018965 ! s-triazine compound metabolic process + +[Term] +id: GO:0018874 +name: benzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid." [ISBN:0721662544] +synonym: "benzoate metabolism" EXACT [] +xref: MetaCyc:P321-PWY +xref: UM-BBD_pathwayID:benz2 +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018875 +name: anaerobic benzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic benzoate metabolism" EXACT [] +xref: MetaCyc:CENTBENZCOA-PWY +xref: UM-BBD_pathwayID:benz +is_a: GO:0018874 ! benzoate metabolic process + +[Term] +id: GO:0018876 +name: benzonitrile metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin." [UM-BBD_pathwayID:bzn] +synonym: "benzonitrile metabolism" EXACT [] +xref: UM-BBD_pathwayID:bzn +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0018877 +name: beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health." [UM-BBD_pathwayID:hch] +synonym: "beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism" EXACT [] +xref: UM-BBD_pathwayID:hch +is_a: GO:0019497 ! hexachlorocyclohexane metabolic process + +[Term] +id: GO:0018878 +name: aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen." [GOC:ai] +synonym: "aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism" EXACT [] +is_a: GO:0018877 ! beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process + +[Term] +id: GO:0018879 +name: biphenyl metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)." [GOC:jl] +synonym: "biphenyl metabolism" EXACT [] +synonym: "xenene metabolic process" EXACT [] +synonym: "xenene metabolism" EXACT [] +xref: UM-BBD_pathwayID:bph +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018880 +name: 4-chlorobiphenyl metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation." [GOC:jl] +synonym: "4-chlorobiphenyl metabolism" EXACT [] +xref: UM-BBD_pathwayID:cbp +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018881 +name: bromoxynil metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants." [GOC:ai] +synonym: "bromoxynil metabolism" EXACT [] +xref: UM-BBD_pathwayID:box +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0018882 +name: (+)-camphor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed." [UM-BBD_pathwayID:cam] +synonym: "(+)-camphor metabolism" EXACT [] +synonym: "camphor metabolic process" EXACT [] +synonym: "camphor metabolism" EXACT [] +xref: UM-BBD_pathwayID:cam +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0018883 +name: caprolactam metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation." [GOC:curators] +synonym: "caprolactam metabolism" EXACT [] +xref: UM-BBD_pathwayID:cap +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0072338 ! cellular lactam metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018884 +name: carbazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen." [GOC:jl] +synonym: "CAR metabolic process" EXACT [] +synonym: "CAR metabolism" EXACT [] +synonym: "carbazole metabolism" EXACT [] +xref: UM-BBD_pathwayID:car +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018885 +name: carbon tetrachloride metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants." [UM-BBD_pathwayID:ctc] +synonym: "carbon tetrachloride metabolism" EXACT [] +xref: UM-BBD_pathwayID:ctc +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018886 +name: anaerobic carbon tetrachloride metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic carbon tetrachloride metabolism" EXACT [] +xref: UM-BBD_pathwayID:ctc +is_a: GO:0018885 ! carbon tetrachloride metabolic process + +[Term] +id: GO:0018887 +name: 4-carboxy-4'-sulfoazobenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid." [PMID:9603860] +synonym: "4-carboxy-4'-sulfoazobenzene metabolism" EXACT [] +synonym: "4-carboxy-4'-sulphoazobenzene metabolic process" EXACT [] +synonym: "4-carboxy-4'-sulphoazobenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:csab +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018888 +name: 3-chloroacrylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid." [GOC:ai] +synonym: "3-chloroacrylic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:caa +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0018889 +name: 2-chloro-N-isopropylacetanilide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants." [UM-BBD_pathwayID:ppc] +synonym: "2-chloro-N-isopropylacetanilide metabolism" EXACT [] +synonym: "propachlor metabolic process" EXACT [] +synonym: "propachlor metabolism" EXACT [] +xref: UM-BBD_pathwayID:ppc +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018890 +name: cyanamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism." [GOC:curators] +synonym: "cyanamide metabolism" EXACT [] +xref: UM-BBD_pathwayID:cnm +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0018891 +name: cyclohexanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent." [ISBN:0721662544] +synonym: "cyclohexanol metabolism" EXACT [] +xref: UM-BBD_pathwayID:chx +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0018892 +name: cyclohexylsulfamate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide." [UM-BBD_pathwayID:chs] +synonym: "cyclohexylsulfamate metabolism" EXACT [] +synonym: "cyclohexylsulphamate metabolic process" EXACT [] +synonym: "cyclohexylsulphamate metabolism" EXACT [] +xref: UM-BBD_pathwayID:chs +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0018893 +name: dibenzofuran metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals." [GOC:ai, UM-BBD_pathwayID:dbf] +synonym: "dibenzofuran metabolism" EXACT [] +xref: UM-BBD_pathwayID:dbf +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018894 +name: dibenzo-p-dioxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern." [UM-BBD_pathwayID:dpd] +synonym: "dibenzo-p-dioxin metabolism" EXACT [] +synonym: "oxanthrene metabolic process" EXACT [] +synonym: "oxanthrene metabolism" EXACT [] +synonym: "phenodioxin metabolic process" EXACT [] +synonym: "phenodioxin metabolism" EXACT [] +xref: UM-BBD_pathwayID:dpd +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018895 +name: dibenzothiophene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion." [PMID:12147483] +synonym: "dibenzothiophene metabolism" EXACT [] +synonym: "diphenylene sulfide metabolic process" EXACT [] +synonym: "diphenylene sulfide metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018896 +name: dibenzothiophene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond." [GOC:ai] +synonym: "dibenzothiophene breakdown" EXACT [] +synonym: "dibenzothiophene catabolism" EXACT [] +synonym: "dibenzothiophene degradation" EXACT [] +xref: UM-BBD_pathwayID:dbt2 +is_a: GO:0018895 ! dibenzothiophene metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0018897 +name: dibenzothiophene desulfurization +namespace: biological_process +def: "The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond." [GOC:ai] +synonym: "dibenzothiophene desulphurization" EXACT [] +xref: MetaCyc:PWY-681 +xref: UM-BBD_pathwayID:dbt +is_a: GO:0018895 ! dibenzothiophene metabolic process + +[Term] +id: GO:0018898 +name: 2,4-dichlorobenzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)." [GOC:jl, UM-BBD_pathwayID:dcb] +synonym: "2,4-dichlorobenzoate metabolism" EXACT [] +xref: UM-BBD_pathwayID:dcb +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018899 +name: 1,2-dichloroethane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride." [GOC:jl] +synonym: "1,2-dichloroethane metabolism" EXACT [] +xref: UM-BBD_pathwayID:dce +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018900 +name: dichloromethane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover." [UM-BBD_pathwayID:dcm] +synonym: "dichloromethane metabolism" EXACT [] +xref: UM-BBD_pathwayID:dcm +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018901 +name: 2,4-dichlorophenoxyacetic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [UM-BBD_pathwayID:2\,4d] +synonym: "2,4-D metabolic process" EXACT [] +synonym: "2,4-D metabolism" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:2\,4-d +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018902 +name: 1,3-dichloro-2-propanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers." [GOC:jl, UM-BBD_pathwayID:dcp] +synonym: "1,3-dichloro-2-propanol metabolism" EXACT [] +synonym: "DCP metabolic process" EXACT [] +synonym: "DCP metabolism" EXACT [] +xref: UM-BBD_pathwayID:dcp +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0044107 ! cellular alcohol metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0018903 +name: 1,3-dichloropropene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes." [UM-BBD_pathwayID:cpr] +synonym: "1,3-dichloropropene metabolism" EXACT [] +synonym: "1,3-dichloropropylene metabolic process" EXACT [] +synonym: "1,3-dichloropropylene metabolism" EXACT [] +synonym: "gamma-chloroallylchloride metabolic process" EXACT [] +synonym: "gamma-chloroallylchloride metabolism" EXACT [] +xref: UM-BBD_pathwayID:cpr +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process + +[Term] +id: GO:0018904 +name: ether metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds." [GOC:pr, ISBN:0198506732] +subset: goslim_pir +synonym: "ether metabolism" EXACT [] +synonym: "organic ether metabolic process" EXACT [] +synonym: "organic ether metabolism" EXACT [] +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018905 +name: dimethyl ether metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications." [UM-BBD_pathwayID:dme] +synonym: "dimethyl ether metabolism" EXACT [] +synonym: "methyl ether metabolic process" EXACT [] +synonym: "methyl ether metabolism" EXACT [] +xref: UM-BBD_pathwayID:dme +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0018904 ! ether metabolic process + +[Term] +id: GO:0018906 +name: methyl tert-butyl ether metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent." [UM-BBD_pathwayID:mtb] +synonym: "methyl tert-butyl ether metabolism" EXACT [] +xref: UM-BBD_pathwayID:mtb +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0018904 ! ether metabolic process + +[Term] +id: GO:0018907 +name: dimethyl sulfoxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing." [GOC:curators] +synonym: "dimethyl sulfoxide metabolism" EXACT [] +synonym: "dimethyl sulphoxide metabolic process" EXACT [] +synonym: "dimethyl sulphoxide metabolism" EXACT [] +synonym: "DMSO metabolic process" EXACT [] +synonym: "DMSO metabolism" EXACT [] +xref: UM-BBD_pathwayID:sulf +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018908 +name: organosulfide cycle +namespace: biological_process +def: "A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle." [UM-BBD_pathwayID:sulf] +synonym: "organosulphide cycle" EXACT [] +xref: UM-BBD_pathwayID:sulf +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0018909 +name: dodecyl sulfate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants." [UM-BBD_pathwayID:dds] +synonym: "dodecyl sulfate metabolism" EXACT [] +synonym: "dodecyl sulphate metabolic process" EXACT [] +synonym: "dodecyl sulphate metabolism" EXACT [] +xref: UM-BBD_pathwayID:dds +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0018910 +name: benzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation." [GOC:ai] +synonym: "benzene metabolism" EXACT [] +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018911 +name: 1,2,4-trichlorobenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides." [http://www.speclab.com/compound/c120821.htm] +synonym: "1,2,4-trichlorobenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tbz +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018912 +name: 1,4-dichlorobenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs." [http://www.speclab.com/compound/c106467.htm] +synonym: "1,4-dichlorobenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:dcz +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018913 +name: anaerobic ethylbenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic ethylbenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:ethb +is_a: GO:0018915 ! ethylbenzene metabolic process + +[Term] +id: GO:0018914 +name: chlorobenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone." [http://www.shsu.edu/] +synonym: "chlorobenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:cb +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018915 +name: ethylbenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels." [http://www.speclab.com/compound/c100414.htm] +synonym: "ethylbenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:ethb2 +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018916 +name: nitrobenzene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline." [GOC:curators] +synonym: "nitrobenzene metabolism" EXACT [] +xref: UM-BBD_pathwayID:nb +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018917 +name: fluorene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents." [UM-BBD_pathwayID:flu] +synonym: "fluorene metabolism" EXACT [] +xref: UM-BBD_pathwayID:flu +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018918 +name: gallate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). The esters and polyesters are widely distributed in angiosperms." [GOC:jl, ISBN:0198506732] +synonym: "gallate metabolism" EXACT [] +synonym: "gallic acid metabolic process" EXACT [] +synonym: "gallic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:gal +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018919 +name: gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health." [UM-BBD_pathwayID:ghch] +synonym: "gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism" EXACT [] +xref: MetaCyc:GAMMAHEXCHLORDEG-PWY +xref: UM-BBD_pathwayID:ghch +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0019497 ! hexachlorocyclohexane metabolic process + +[Term] +id: GO:0018920 +name: glyphosate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond." [UM-BBD_pathwayID:gly] +synonym: "glyphosate metabolism" EXACT [] +synonym: "Roundup metabolic process" EXACT [] +synonym: "Roundup metabolism" EXACT [] +xref: UM-BBD_pathwayID:gly +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0018921 +name: 3-hydroxybenzyl alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum." [UM-BBD_pathwayID:mcr] +synonym: "3-hydroxybenzyl alcohol metabolism" EXACT [] +xref: UM-BBD_pathwayID:mcr +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0018922 +name: iprodione metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium)." [UM-BBD_pathwayID:ipd] +synonym: "iprodione metabolism" EXACT [] +xref: UM-BBD_pathwayID:ipd +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0052803 ! imidazole-containing compound metabolic process + +[Term] +id: GO:0018923 +name: limonene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene." [UM-BBD_pathwayID:lim] +synonym: "limonene metabolism" EXACT [] +xref: UM-BBD_pathwayID:lim +is_a: GO:0043692 ! monoterpene metabolic process +is_a: GO:1900673 ! olefin metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018924 +name: mandelate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic." [GOC:jl] +synonym: "mandelate metabolism" EXACT [] +synonym: "mandelic acid metabolic process" EXACT [] +synonym: "mandelic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:mca +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0018925 +name: m-cresol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes." [GOC:jl] +synonym: "3-hydroxytoluene metabolic process" EXACT [] +synonym: "3-hydroxytoluene metabolism" EXACT [] +synonym: "m-cresol metabolism" EXACT [] +synonym: "meta-cresol metabolic process" EXACT [] +synonym: "meta-cresol metabolism" EXACT [] +xref: MetaCyc:M-CRESOL-DEGRADATION-PWY +xref: UM-BBD_pathwayID:mcr +is_a: GO:0042212 ! cresol metabolic process + +[Term] +id: GO:0018926 +name: methanesulfonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide." [UM-BBD_pathwayID:msa] +synonym: "methanesulfonic acid metabolism" EXACT [] +synonym: "methanesulphonic acid metabolic process" EXACT [] +synonym: "methanesulphonic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:msa +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0019694 ! alkanesulfonate metabolic process + +[Term] +id: GO:0018927 +name: obsolete methionine and threonine metabolic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because its use of 'and' was causing violations to the true-path rule. +synonym: "methionine and threonine metabolic process" EXACT [] +is_obsolete: true +consider: GO:0006555 +consider: GO:0006566 + +[Term] +id: GO:0018928 +name: methyl ethyl ketone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints." [UM-BBD_pathwayID:mek] +synonym: "2-butanone metabolic process" EXACT [] +synonym: "2-butanone metabolism" EXACT [] +synonym: "MEK metabolic process" EXACT [] +synonym: "MEK metabolism" EXACT [] +synonym: "methyl ethyl ketone metabolism" EXACT [] +xref: UM-BBD_pathwayID:mek +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0018929 +name: methyl fluoride metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils." [UM-BBD_pathwayID:mf] +synonym: "methyl fluoride metabolism" EXACT [] +xref: UM-BBD_pathwayID:mf +is_a: GO:0042197 ! halogenated hydrocarbon metabolic process + +[Term] +id: GO:0018930 +name: 3-methylquinoline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring." [GOC:ai] +synonym: "3-methylquinoline metabolism" EXACT [] +xref: UM-BBD_pathwayID:mqn +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018931 +name: naphthalene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide." [http://www.iversonsoftware.com/reference/chemistry/n/Naphthalene.htm] +synonym: "naphthalene metabolism" EXACT [] +xref: UM-BBD_pathwayID:naph +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0090420 ! naphthalene-containing compound metabolic process + +[Term] +id: GO:0018933 +name: nicotine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine." [GOC:sm, ISBN:0198547684] +synonym: "nicotine metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0018934 +name: nitrilotriacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment." [UM-BBD_pathwayID:nta] +synonym: "nitrilotriacetate metabolism" EXACT [] +xref: UM-BBD_pathwayID:nta +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018935 +name: aerobic nitrilotriacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen." [GOC:ai] +synonym: "aerobic nitrilotriacetate metabolism" EXACT [] +is_a: GO:0018934 ! nitrilotriacetate metabolic process + +[Term] +id: GO:0018936 +name: anaerobic nitrilotriacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic nitrilotriacetate metabolism" EXACT [] +is_a: GO:0018934 ! nitrilotriacetate metabolic process + +[Term] +id: GO:0018937 +name: nitroglycerin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates." [UM-BBD_pathwayID:ng] +synonym: "NG metabolic process" EXACT [] +synonym: "NG metabolism" EXACT [] +synonym: "nitroglycerin metabolism" EXACT [] +xref: MetaCyc:P201-PWY +xref: UM-BBD_pathwayID:ng +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018938 +name: 2-nitropropane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol." [UM-BBD_pathwayID:npp] +synonym: "2-nitropropane metabolism" EXACT [] +xref: MetaCyc:PWY-723 +xref: UM-BBD_pathwayID:npp +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018939 +name: n-octane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System." [UM-BBD_pathwayID:oct] +synonym: "n-octane metabolism" EXACT [] +xref: UM-BBD_pathwayID:oct +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0043446 ! cellular alkane metabolic process + +[Term] +id: GO:0018940 +name: orcinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants." [GOC:jl] +synonym: "orcin metabolic process" EXACT [] +synonym: "orcin metabolism" EXACT [] +synonym: "orcinol metabolism" EXACT [] +xref: MetaCyc:P342-PWY +xref: UM-BBD_pathwayID:orc +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0018941 +name: organomercury metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom." [ISBN:0198506732] +synonym: "organomercury metabolism" EXACT [] +xref: UM-BBD_pathwayID:ogm +is_a: GO:0018942 ! organometal metabolic process + +[Term] +id: GO:0018942 +name: organometal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms." [ISBN:0198506732] +subset: goslim_pir +synonym: "organometal metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018943 +name: organotin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organotin, an organic compound containing a tin atom." [ISBN:0198506732] +synonym: "organotin metabolism" EXACT [] +is_a: GO:0018942 ! organometal metabolic process + +[Term] +id: GO:0018944 +name: tri-n-butyltin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms." [GOC:ai, UM-BBD_pathwayID:tbt] +synonym: "tri-n-butyltin metabolism" EXACT [] +xref: UM-BBD_pathwayID:tbt +is_a: GO:0018943 ! organotin metabolic process + +[Term] +id: GO:0018945 +name: organosilicon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon." [GOC:jl] +synonym: "organosilicon metabolism" EXACT [] +synonym: "organosilicone metabolic process" EXACT [] +synonym: "organosilicone metabolism" EXACT [] +xref: UM-BBD_pathwayID:osi +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018946 +name: aerobic organosilicon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen." [GOC:jl] +synonym: "aerobic organosilicon metabolism" EXACT [] +synonym: "aerobic organosilicone metabolic process" EXACT [] +synonym: "aerobic organosilicone metabolism" EXACT [] +xref: UM-BBD_pathwayID:osi +is_a: GO:0018945 ! organosilicon metabolic process + +[Term] +id: GO:0018947 +name: anaerobic organosilicon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen." [GOC:jl] +synonym: "anaerobic organosilicon metabolism" EXACT [] +synonym: "anaerobic organosilicone metabolic process" EXACT [] +synonym: "anaerobic organosilicone metabolism" EXACT [] +xref: UM-BBD_pathwayID:osi +is_a: GO:0018945 ! organosilicon metabolic process + +[Term] +id: GO:0018948 +name: xylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene." [GOC:jl] +synonym: "xylene metabolism" EXACT [] +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018949 +name: m-xylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon." [GOC:jl] +synonym: "m-xylene metabolism" EXACT [] +synonym: "meta-xylene metabolic process" EXACT [] +synonym: "meta-xylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:mxy +is_a: GO:0018948 ! xylene metabolic process + +[Term] +id: GO:0018950 +name: o-xylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon." [GOC:jl] +synonym: "o-xylene metabolism" EXACT [] +synonym: "ortho-xylene metabolic process" EXACT [] +synonym: "ortho-xylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:oxy +is_a: GO:0018948 ! xylene metabolic process + +[Term] +id: GO:0018951 +name: p-xylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon." [GOC:jl] +synonym: "p-xylene metabolism" EXACT [] +synonym: "para-xylene metabolic process" EXACT [] +synonym: "para-xylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:pxy +is_a: GO:0018948 ! xylene metabolic process + +[Term] +id: GO:0018952 +name: parathion metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [UM-BBD_pathwayID:pthn] +synonym: "parathion metabolism" EXACT [] +xref: UM-BBD_pathwayID:pthn +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0019637 ! organophosphate metabolic process + +[Term] +id: GO:0018953 +name: p-cymene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants." [UM-BBD_pathwayID:pcy] +synonym: "p-cymene metabolism" EXACT [] +xref: UM-BBD_pathwayID:pcy +is_a: GO:0043692 ! monoterpene metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0018954 +name: pentaerythritol tetranitrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator." [UM-BBD_pathwayID:petn] +synonym: "pentaerythritol tetranitrate metabolism" EXACT [] +xref: UM-BBD_pathwayID:petn +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0018955 +name: phenanthrene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish." [GOC:jl, UM-BBD_pathwayID:pha] +synonym: "phenanthrene metabolism" EXACT [] +xref: UM-BBD_pathwayID:pha +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0018956 +name: phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite." [UM-BBD_pathwayID:pha3] +synonym: "phenanthrene breakdown via trans-9(R),10(R)-dihydrodiolphenanthrene" EXACT [] +synonym: "phenanthrene degradation via trans-9(R),10(R)-dihydrodiolphenanthrene" EXACT [] +xref: UM-BBD_pathwayID:pha3 +is_a: GO:0042216 ! phenanthrene catabolic process + +[Term] +id: GO:0018957 +name: phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite." [UM-BBD_pathwayID:pha2] +synonym: "phenanthrene breakdown via trans-9(S),10(S)-dihydrodiolphenanthrene" EXACT [] +synonym: "phenanthrene degradation via trans-9(S),10(S)-dihydrodiolphenanthrene" EXACT [] +xref: UM-BBD_pathwayID:pha2 +is_a: GO:0042216 ! phenanthrene catabolic process + +[Term] +id: GO:0018958 +name: phenol-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] +comment: Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds. +synonym: "carbolic acid metabolic process" EXACT [] +synonym: "carbolic acid metabolism" EXACT [] +synonym: "hydroxybenzene metabolic process" EXACT [] +synonym: "hydroxybenzene metabolism" EXACT [] +synonym: "phenol-containing compound metabolism" EXACT [] +xref: UM-BBD_pathwayID:phe +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0018959 +name: aerobic phenol-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen." [ISBN:0198506732] +synonym: "aerobic phenol-containing compound metabolism" EXACT [] +xref: UM-BBD_pathwayID:pba +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0018960 +name: 4-nitrophenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion." [GOC:jl] +synonym: "4-nitrophenol metabolism" EXACT [] +synonym: "p-nitrophenol metabolic process" EXACT [] +synonym: "p-nitrophenol metabolism" EXACT [] +xref: UM-BBD_pathwayID:nphe +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0018961 +name: pentachlorophenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms." [UM-BBD_pathwayID:pcp] +synonym: "PCP metabolic process" EXACT [] +synonym: "PCP metabolism" EXACT [] +synonym: "pentachlorophenol metabolism" EXACT [] +xref: UM-BBD_pathwayID:pcp +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018962 +name: 3-phenylpropionate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins." [GOC:ai, UM-BBD_pathwayID:ppa] +synonym: "3-phenylpropionate metabolism" EXACT [] +synonym: "hydrocinnamic acid metabolic process" EXACT [] +synonym: "hydrocinnamic acid metabolism" EXACT [] +synonym: "phenylpropanoate metabolic process" EXACT [] +synonym: "phenylpropanoate metabolism" EXACT [] +xref: UM-BBD_pathwayID:ppa +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018963 +name: phthalate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses." [UM-BBD_pathwayID:pth] +synonym: "phthalate metabolism" EXACT [] +synonym: "phthalic acid metabolic process" EXACT [] +synonym: "phthalic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:pth +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0018964 +name: propylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals." [GOC:jl] +synonym: "propylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:pro +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0043449 ! cellular alkene metabolic process + +[Term] +id: GO:0018965 +name: s-triazine compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms." [UM-BBD_pathwayID:tria] +synonym: "s-triazine compound metabolism" EXACT [] +xref: UM-BBD_pathwayID:tria +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0018966 +name: styrene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen." [GOC:jl, UM-BBD_pathwayID:sty] +synonym: "styrene metabolism" EXACT [] +xref: UM-BBD_pathwayID:sty +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:1900673 ! olefin metabolic process + +[Term] +id: GO:0018967 +name: tetrachloroethylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent." [http://www.who.int/water_sanitation_health/GDWQ/Chemicals/tetrachloroethenesum.htm] +synonym: "tetrachloroethene metabolic process" EXACT [] +synonym: "tetrachloroethene metabolism" EXACT [] +synonym: "tetrachloroethylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tce2 +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process + +[Term] +id: GO:0018968 +name: tetrahydrofuran metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems." [UM-BBD_pathwayID:thf] +synonym: "tetrahydrofuran metabolism" EXACT [] +synonym: "THF metabolic process" EXACT [] +synonym: "THF metabolism" EXACT [] +xref: UM-BBD_pathwayID:thf +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0097176 ! epoxide metabolic process + +[Term] +id: GO:0018969 +name: thiocyanate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries." [GOC:jl] +synonym: "thiocyanate metabolism" EXACT [] +synonym: "thiocyanic acid metabolic process" EXACT [] +synonym: "thiocyanic acid metabolism" EXACT [] +xref: MetaCyc:P581-PWY +xref: UM-BBD_pathwayID:thc +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process + +[Term] +id: GO:0018970 +name: toluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications." [UM-BBD_pathwayID:tol] +synonym: "methylbenzene metabolic process" EXACT [] +synonym: "methylbenzene metabolism" EXACT [] +synonym: "toluene metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0018971 +name: anaerobic toluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic toluene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tol2 +is_a: GO:0018970 ! toluene metabolic process + +[Term] +id: GO:0018972 +name: toluene-4-sulfonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water." [GOC:ai] +synonym: "4-methylbenzenesulfonate metabolic process" EXACT [] +synonym: "4-methylbenzenesulfonate metabolism" EXACT [] +synonym: "4-toluenesulfonate metabolic process" EXACT [] +synonym: "4-toluenesulfonate metabolism" EXACT [] +synonym: "toluene-4-sulfonate metabolism" EXACT [] +synonym: "toluene-4-sulphonate metabolic process" EXACT [] +synonym: "toluene-4-sulphonate metabolism" EXACT [] +xref: MetaCyc:TOLSULFDEG-PWY +xref: UM-BBD_pathwayID:tsa +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0018973 +name: trinitrotoluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene." [GOC:ai] +synonym: "trinitrotoluene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tnt +is_a: GO:0019326 ! nitrotoluene metabolic process + +[Term] +id: GO:0018974 +name: 2,4,6-trinitrotoluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives." [ISBN:0333781767] +synonym: "2,4,6-trinitrotoluene metabolism" EXACT [] +synonym: "TNT metabolic process" EXACT [] +synonym: "TNT metabolism" EXACT [] +is_a: GO:0018973 ! trinitrotoluene metabolic process + +[Term] +id: GO:0018975 +name: anaerobic 2,4,6-trinitrotoluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen." [GOC:ai] +synonym: "anaerobic 2,4,6-trinitrotoluene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tnt2 +is_a: GO:0018974 ! 2,4,6-trinitrotoluene metabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0018976 +name: 1,2,3-tribromopropane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture." [GOC:jl] +synonym: "1,2,3-tribromopropane metabolism" EXACT [] +xref: UM-BBD_pathwayID:tbp +is_a: GO:0042197 ! halogenated hydrocarbon metabolic process + +[Term] +id: GO:0018977 +name: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide." [GOC:jl] +synonym: "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism" EXACT [] +synonym: "DDT metabolic process" EXACT [] +synonym: "DDT metabolism" EXACT [] +xref: UM-BBD_pathwayID:ddt +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018978 +name: anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen." [GOC:jl] +synonym: "anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism" EXACT [] +synonym: "anaerobic DDT metabolic process" EXACT [] +synonym: "anaerobic DDT metabolism" EXACT [] +xref: UM-BBD_pathwayID:ddt2 +is_a: GO:0018977 ! 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process + +[Term] +id: GO:0018979 +name: trichloroethylene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent." [GOC:jl] +synonym: "TCE metabolic process" EXACT [] +synonym: "TCE metabolism" EXACT [] +synonym: "trichloroethene metabolic process" EXACT [] +synonym: "trichloroethene metabolism" EXACT [] +synonym: "trichloroethylene metabolism" EXACT [] +xref: UM-BBD_pathwayID:tce +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process + +[Term] +id: GO:0018980 +name: 2,4,5-trichlorophenoxyacetic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns." [UM-BBD_pathwayID:2\,4\,5-t] +synonym: "2,4,5-T metabolic process" EXACT [] +synonym: "2,4,5-T metabolism" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid metabolism" EXACT [] +xref: UM-BBD_pathwayID:2\,4\,5-t +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018981 +name: triethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent." [GOC:jl] +synonym: "triethanolamine metabolism" EXACT [] +xref: UM-BBD_pathwayID:tea +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0044106 ! cellular amine metabolic process +is_a: GO:0044107 ! cellular alcohol metabolic process + +[Term] +id: GO:0018982 +name: vanillin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin." [GOC:jl] +synonym: "vanillic aldehyde metabolic process" EXACT [] +synonym: "vanillic aldehyde metabolism" EXACT [] +synonym: "vanillin metabolism" EXACT [] +xref: UM-BBD_pathwayID:van +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0018983 +name: Z-phenylacetaldoxime metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants." [UM-BBD_pathwayID:car] +synonym: "Z-phenylacetaldoxime metabolism" EXACT [] +xref: UM-BBD_pathwayID:pao +is_a: GO:0019330 ! aldoxime metabolic process + +[Term] +id: GO:0018984 +name: naphthalenesulfonate metabolic process +namespace: biological_process +alt_id: GO:0018932 +def: "The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene." [GOC:ai] +synonym: "naphthalenesulfonate metabolism" EXACT [] +synonym: "naphthalenesulphonate metabolic process" EXACT [] +synonym: "naphthalenesulphonate metabolism" EXACT [] +xref: UM-BBD_pathwayID:nphs +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0018985 +name: pronuclear envelope synthesis +namespace: biological_process +def: "Synthesis and ordering of the envelope of pronuclei." [GOC:ems] +is_a: GO:0006998 ! nuclear envelope organization +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0018988 +name: obsolete molting cycle, protein-based cuticle +namespace: biological_process +def: "OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss." [GOC:ems, GOC:mtg_sensu] +comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term. +synonym: "protein-based cuticle molting cycle" EXACT [GOC:dph, GOC:tb] +is_obsolete: true +consider: GO:0007591 +consider: GO:0018996 + +[Term] +id: GO:0018989 +name: apolysis +namespace: biological_process +def: "The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells." [GOC:jl] +xref: Wikipedia:Apolysis +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle + +[Term] +id: GO:0018990 +name: ecdysis, chitin-based cuticle +namespace: biological_process +def: "The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle + +[Term] +id: GO:0018991 +name: oviposition +namespace: biological_process +alt_id: GO:0060403 +def: "The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water." [GOC:ems] +synonym: "egg laying" BROAD [] +synonym: "egg-laying" BROAD [] +synonym: "post-mating oviposition" NARROW [] +xref: Wikipedia:Oviposition +is_a: GO:0019098 ! reproductive behavior + +[Term] +id: GO:0018992 +name: germ-line sex determination +namespace: biological_process +def: "The determination of sex and sexual phenotype in an organism's germ line." [GOC:ems] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0018993 +name: somatic sex determination +namespace: biological_process +def: "The determination of sex and sexual phenotypes in an organism's soma." [GOC:ems] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0018995 +name: host cellular component +namespace: cellular_component +def: "Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection." [ISBN:0198506732] +synonym: "host organism" EXACT [] +xref: Wikipedia:Host_(biology) +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0018996 +name: molting cycle, collagen and cuticulin-based cuticle +namespace: biological_process +def: "The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans." [GOC:jl, GOC:mtg_sensu] +synonym: "collagen and cuticulin-based cuticle molting cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0042303 ! molting cycle + +[Term] +id: GO:0018997 +name: obsolete electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because the parent terms cover its function. +synonym: "electron transfer carrier" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0018998 +name: obsolete metaxin +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a single gene product and not a complex. +synonym: "metaxin" EXACT [] +is_obsolete: true +consider: GO:0005741 + +[Term] +id: GO:0019000 +name: obsolete endonuclease G activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [PMID:12444964, PMID:12928502, PMID:12941691] +comment: This term was made obsolete because it represents a gene product. +synonym: "endonuclease G activity" EXACT [] +is_obsolete: true +consider: GO:0004520 +consider: GO:0004521 + +[Term] +id: GO:0019001 +name: guanyl nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate." [ISBN:0198506732] +xref: Reactome:R-HSA-156909 "eEF1A complexes with GTP" +is_a: GO:0017076 ! purine nucleotide binding + +[Term] +id: GO:0019002 +name: GMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with GMP, guanosine monophosphate." [GOC:ai] +is_a: GO:0032550 ! purine ribonucleoside binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0019003 +name: GDP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate." [GOC:ai] +is_a: GO:0032550 ! purine ribonucleoside binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0019005 +name: SCF ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] +synonym: "CDL1 complex" EXACT [] +synonym: "CRL1 complex" EXACT [] +synonym: "Cul1-RING ubiquitin ligase complex" EXACT [] +synonym: "cullin-RING ligase 1" EXACT [] +synonym: "SCF complex" EXACT [] +synonym: "SCF complex substrate recognition subunit" NARROW [] +synonym: "Skp1/Cul1/F-box protein complex" EXACT [] +xref: Wikipedia:SCF_complex +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0019008 +name: molybdopterin synthase complex +namespace: cellular_component +alt_id: GO:0019009 +def: "A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits." [GOC:mah, PMID:12571227, PMID:15709772] +subset: goslim_metagenomics +synonym: "molybdopterin converting factor complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0019010 +name: farnesoic acid O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine." [PMID:12135499] +synonym: "S-adenosyl-methionine:farnesoic acid O-methyltransferase activity" EXACT [] +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0019011 +name: obsolete DNA replication accessory factor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it does not represent a true molecular function. +synonym: "DNA replication accessory factor" EXACT [] +is_obsolete: true +consider: GO:0006260 + +[Term] +id: GO:0019012 +name: virion +namespace: cellular_component +def: "The complete fully infectious extracellular virus particle." [ISBN:0781718325] +subset: goslim_chembl +subset: goslim_metagenomics +subset: goslim_pir +synonym: "complete virus particle" EXACT [] +xref: Wikipedia:Virus +is_a: GO:0005575 ! cellular_component +property_value: RO:0002161 NCBITaxon:131567 + +[Term] +id: GO:0019013 +name: viral nucleocapsid +namespace: cellular_component +alt_id: GO:0019014 +def: "The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle." [ISBN:0781702534] +subset: goslim_chembl +synonym: "core" BROAD [] +synonym: "nucleocapsid" EXACT [] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019028 ! viral capsid + +[Term] +id: GO:0019015 +name: obsolete viral genome +namespace: cellular_component +def: "OBSOLETE. The whole of the genetic information of a virus, contained as either DNA or RNA." [ISBN:0198506732] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019016 +name: obsolete non-segmented viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome that consists of one continuous nucleic acid molecule." [GOC:pk] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019017 +name: obsolete segmented viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019018 +name: obsolete bipartite viral genome +namespace: cellular_component +def: "OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019019 +name: obsolete tripartite viral genome +namespace: cellular_component +def: "OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019020 +name: obsolete multipartite viral genome +namespace: cellular_component +def: "OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019021 +name: obsolete DNA viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome composed of deoxyribonucleic acid." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019022 +name: obsolete RNA viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019023 +name: obsolete dsRNA viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome composed of double stranded RNA." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019024 +name: obsolete ssRNA viral genome +namespace: cellular_component +def: "OBSOLETE. A viral genome composed of single stranded RNA of either positive or negative sense." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019025 +name: obsolete positive sense viral genome +namespace: cellular_component +def: "OBSOLETE. A single stranded RNA genome with the same nucleotide polarity as mRNA." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019026 +name: obsolete negative sense viral genome +namespace: cellular_component +def: "OBSOLETE. A single stranded RNA genome with the opposite nucleotide polarity as mRNA." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019027 +name: obsolete ambisense viral genome +namespace: cellular_component +def: "OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +is_obsolete: true + +[Term] +id: GO:0019028 +name: viral capsid +namespace: cellular_component +alt_id: GO:0046728 +def: "The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres." [GOC:mtg_sensu, ISBN:0198506732] +subset: goslim_chembl +xref: Wikipedia:Capsid +is_a: GO:0044423 ! virion part + +[Term] +id: GO:0019029 +name: helical viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure." [ISBN:071673706X, UniProtKB-KW:KW-1139, VZ:885] +is_a: GO:0019028 ! viral capsid + +[Term] +id: GO:0019030 +name: icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure." [GOC:bm, ISBN:0198506732, ISBN:071673706X, VZ:885, Wikipedia:Capsid] +synonym: "quasispherical viral capsid" EXACT [] +is_a: GO:0019028 ! viral capsid + +[Term] +id: GO:0019031 +name: viral envelope +namespace: cellular_component +def: "The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins." [GOC:bf, GOC:bm, GOC:jl, ISBN:0781718325, Wikipedia:Viral_envelope] +subset: goslim_chembl +synonym: "viral glycoprotein" RELATED [] +synonym: "viral outside membrane" EXACT [] +xref: Wikipedia:Viral_envelope +is_a: GO:0036338 ! viral membrane + +[Term] +id: GO:0019032 +name: obsolete viral glycoprotein +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a type of gene product and not a location or complex. +synonym: "viral glycoprotein" EXACT [] +is_obsolete: true +consider: GO:0019031 + +[Term] +id: GO:0019033 +name: viral tegument +namespace: cellular_component +def: "A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically." [ISBN:0721662544] +xref: Wikipedia:Viral_tegument +is_a: GO:0044423 ! virion part + +[Term] +id: GO:0019034 +name: viral replication complex +namespace: cellular_component +def: "Specific locations and structures in the virus infected cell involved in replicating the viral genome." [ISBN:0781718325] +is_a: GO:0044094 ! host cell nuclear part + +[Term] +id: GO:0019035 +name: viral integration complex +namespace: cellular_component +def: "A nucleoprotein complex containing viral genetic material and associated viral and host proteins, which is capable of inserting a viral genome into a host genome." [ISBN:0781718325, PMID:16712776, Wikipedia:Pre-integration_complex] +synonym: "PIC" EXACT [PMID:16712776] +synonym: "pre-integration complex" EXACT [PMID:16712776] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0042025 ! host cell nucleus + +[Term] +id: GO:0019036 +name: viral transcriptional complex +namespace: cellular_component +def: "Specific locations and structures in the virus infected cell involved in transcribing the viral genome." [ISBN:0781718325] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0019037 +name: viral assembly intermediate +namespace: cellular_component +def: "Specific locations and structures in the virus infected cell involved in assembling new virions." [ISBN:0781718325] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0019038 +name: obsolete provirus +namespace: cellular_component +def: "OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle." [ISBN:0121585336] +comment: This term was obsoleted because it does not represent a GO cellular component. +xref: Wikipedia:Provirus +is_obsolete: true + +[Term] +id: GO:0019039 +name: obsolete viral-cell fusion molecule activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "viral-cell fusion molecule activity" EXACT [] +is_obsolete: true +consider: GO:0019064 +consider: GO:0050839 + +[Term] +id: GO:0019040 +name: obsolete viral host shutoff protein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "viral host shutoff protein" EXACT [] +is_obsolete: true +consider: GO:0004534 +consider: GO:0019057 + +[Term] +id: GO:0019042 +name: viral latency +namespace: biological_process +alt_id: GO:0030069 +alt_id: GO:0075710 +def: "The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate." [GOC:jl] +synonym: "latent virus infection" EXACT [] +synonym: "phage lysogeny" EXACT [] +synonym: "viral dormancy" EXACT [] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0019043 +name: establishment of viral latency +namespace: biological_process +alt_id: GO:0075601 +def: "A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects." [GOC:jl] +synonym: "lysogenic commitment" EXACT [] +synonym: "phage lysogeny" NARROW [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019042 ! viral latency + +[Term] +id: GO:0019044 +name: maintenance of viral latency +namespace: biological_process +alt_id: GO:0032360 +alt_id: GO:0075716 +def: "The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms." [GOC:jl] +synonym: "latent virus maintenance" EXACT [] +synonym: "prophage maintenance" EXACT [] +synonym: "provirus maintenance" EXACT [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019042 ! viral latency + +[Term] +id: GO:0019045 +name: latent virus replication +namespace: biological_process +def: "Any process required for latent viral replication in a cell." [ISBN:0781702534] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019042 ! viral latency + +[Term] +id: GO:0019046 +name: release from viral latency +namespace: biological_process +alt_id: GO:0075717 +def: "The process by which a virus begins to replicate following a latency replication decision (switch)." [GOC:dos, GOC:jl] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019045 ! latent virus replication + +[Term] +id: GO:0019048 +name: modulation by virus of host process +namespace: biological_process +alt_id: GO:0044661 +alt_id: GO:0044792 +def: "The process in which a virus effects a change in the structure or processes of its host organism." [GOC:bf, GOC:jl, ISBN:0781718325, UniProtKB-KW:KW-0945] +synonym: "disruption by virus of host cell" RELATED [] +synonym: "host-virus interaction" EXACT [GOC:bf, GOC:jl] +synonym: "modulation by virus of host anatomical structure or process" RELATED [GOC:bf, GOC:jl] +synonym: "modulation by virus of host anatomy or process" EXACT [GOC:bf, GOC:jl] +synonym: "modulation by virus of host morphology or physiology" RELATED [] +synonym: "viral interaction with host" EXACT [] +synonym: "viral-host process" EXACT [GOC:bf, GOC:jl] +synonym: "virus-host interaction" BROAD [GOC:bf, GOC:jl] +synonym: "virus-host process" EXACT [GOC:bf, GOC:jl] +xref: VZ:886 "Vertebrate host-virus interactions" +is_a: GO:0016032 ! viral process +is_a: GO:0044003 ! modulation by symbiont of host process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18719 xsd:anyURI +created_by: jl +creation_date: 2012-08-01T13:41:00Z + +[Term] +id: GO:0019049 +name: mitigation of host defenses by virus +namespace: biological_process +def: "A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:1555811272] +synonym: "evasion of host defenses by virus" NARROW [GOC:bf, GOC:bm, GOC:jl] +synonym: "evasion or tolerance of host defenses by virus" RELATED [] +synonym: "viral host defence evasion" NARROW [] +synonym: "viral host defense evasion" NARROW [] +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0030682 ! mitigation of host defenses by symbiont + +[Term] +id: GO:0019050 +name: suppression by virus of host apoptotic process +namespace: biological_process +def: "Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication." [GOC:mtg_apoptosis, ISBN:0781718325] +synonym: "negative regulation by virus of host apoptosis" EXACT [] +synonym: "negative regulation of apoptosis by virus" EXACT [] +synonym: "suppression by virus of host apoptosis" EXACT [] +synonym: "suppression of apoptosis in host by virus" EXACT [] +is_a: GO:0033668 ! negative regulation by symbiont of host apoptotic process +is_a: GO:0039526 ! modulation by virus of host apoptotic process + +[Term] +id: GO:0019051 +name: induction by virus of host apoptotic process +namespace: biological_process +def: "The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions." [GOC:mtg_apoptosis, ISBN:0781718325] +synonym: "activation by virus of host apoptosis" EXACT [] +synonym: "activation by virus of host apoptotic programmed cell death" EXACT [] +synonym: "activation of apoptosis in host by virus" EXACT [] +synonym: "induction by virus of host apoptosis" NARROW [] +synonym: "induction by virus of host apoptotic programmed cell death" EXACT [] +synonym: "induction of apoptosis in host by virus" EXACT [] +is_a: GO:0060139 ! positive regulation of apoptotic process by virus + +[Term] +id: GO:0019054 +name: modulation by virus of host cellular process +namespace: biological_process +def: "The process in which a virus effects a change in the processes and activities of its host organism." [GOC:jl] +synonym: "modification by virus of host cellular process" EXACT [] +synonym: "modulation by virus of host process" BROAD [] +synonym: "modulation of cellular process in host by virus" RELATED [] +synonym: "regulation by virus of host cellular process" EXACT [] +synonym: "regulation of cellular process in host by virus" EXACT [] +synonym: "regulation of host cellular process by virus" EXACT [] +synonym: "viral host cell process manipulation" EXACT [] +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0009987 ! cellular process + +[Term] +id: GO:0019055 +name: modification by virus of host cell cycle regulation +namespace: biological_process +def: "Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication." [GOC:dph, ISBN:0781718325] +synonym: "viral perturbation of cell cycle regulation" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0044071 ! modulation by symbiont of host cell cycle +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0022402 ! cell cycle process + +[Term] +id: GO:0019056 +name: modulation by virus of host transcription +namespace: biological_process +def: "Any process in which a virus modulates the frequency, rate or extent of its host's transcription." [ISBN:0781718325] +synonym: "modification by virus of host transcription" EXACT [] +synonym: "viral perturbation of host cell transcription" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0039656 ! modulation by virus of host gene expression +is_a: GO:0052026 ! modulation by symbiont of host transcription + +[Term] +id: GO:0019057 +name: modulation by virus of host translation +namespace: biological_process +def: "Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA." [ISBN:0781718325] +synonym: "host cell protein synthesis shutoff" BROAD [] +synonym: "host cell shutoff" BROAD [] +synonym: "modification by virus of host cell mRNA translation" EXACT [] +synonym: "modulation of host translation by virus" EXACT [GOC:bf] +synonym: "regulation of host mRNA translation by virus" EXACT [] +synonym: "regulation of host translation by virus" EXACT [] +synonym: "regulation of translation in host by virus" EXACT [] +synonym: "viral host shutoff protein" RELATED [] +synonym: "viral perturbation of host cell mRNA translation" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0039656 ! modulation by virus of host gene expression +is_a: GO:0044073 ! modulation by symbiont of host translation + +[Term] +id: GO:0019058 +name: viral life cycle +namespace: biological_process +alt_id: GO:0019067 +def: "A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome." [ISBN:1555811272] +synonym: "lytic viral life cycle" RELATED [] +synonym: "viral assembly, maturation, egress, and release" NARROW [GOC:bf, GOC:jl] +synonym: "viral infectious cycle" RELATED [GOC:bf, GOC:jl] +synonym: "viral replication" RELATED [GOC:bf, GOC:jl] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0019059 +name: obsolete initiation of viral infection +namespace: biological_process +def: "OBSOLETE. The set of processes involved in the start of virus infection of cells." [ISBN:0781702534] +comment: This term was made obsolete because it is ambiguous, and more specific terms have been created. +synonym: "initiation of viral infection" EXACT [] +is_obsolete: true +consider: GO:0046718 + +[Term] +id: GO:0019060 +name: intracellular transport of viral protein in host cell +namespace: biological_process +alt_id: GO:0046742 +alt_id: GO:0046743 +alt_id: GO:0046801 +def: "The directed movement of a viral protein within the host cell." [GOC:ai, ISBN:0781702534, ISBN:0781718325, PMID:11581394, PMID:9188566] +comment: This term is for annotation of proteins responsible for the movement of individual viral proteins, rather than the whole viral particle. +synonym: "cytoplasmic viral capsid transport" NARROW [] +synonym: "intracellular transport of viral capsid in host cell" NARROW [] +synonym: "intracellular transport of viral capsid protein in host cell" NARROW [] +synonym: "intracellular transport of viral proteins in host cell" EXACT [] +synonym: "intracellular viral capsid transport" NARROW [] +synonym: "intracellular viral protein transport" EXACT [] +synonym: "nuclear viral capsid transport" NARROW [] +synonym: "viral capsid transport in host cell cytoplasm" NARROW [] +synonym: "viral capsid transport in host cell nucleus" NARROW [] +is_a: GO:0030581 ! symbiont intracellular protein transport in host +is_a: GO:0044766 ! multi-organism transport +relationship: part_of GO:0046719 ! regulation by virus of viral protein levels in host cell + +[Term] +id: GO:0019061 +name: uncoating of virus +namespace: biological_process +def: "The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome." [GOC:plm, ISBN:0781702534, PMID:8162442] +synonym: "viral uncoating" EXACT [PMID:8162442] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0019062 +name: virion attachment to host cell +namespace: biological_process +def: "The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1161, VZ:956] +synonym: "viral absorption" EXACT [] +synonym: "viral attachment to host cell" RELATED [GOC:bf, GOC:jl] +synonym: "virion attachment to host cell surface receptor" NARROW [] +xref: VZ:956 "Viral attachment to host cell" +is_a: GO:0044650 ! adhesion of symbiont to host cell +relationship: has_part GO:0046790 ! virion binding +relationship: has_part GO:0046812 ! host cell surface binding +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0019064 +name: fusion of virus membrane with host plasma membrane +namespace: biological_process +alt_id: GO:0075706 +def: "Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm." [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:bf, GOC:jl] +synonym: "viral envelope fusion" BROAD [] +synonym: "viral envelope fusion with host cell membrane" EXACT [] +synonym: "viral envelope fusion with host membrane" EXACT [] +synonym: "viral envelope fusion with host plasma membrane" EXACT [] +synonym: "viral penetration via membrane fusion" BROAD [] +synonym: "viral-cell fusion molecule activity" RELATED [] +xref: VZ:987 "Fusion of virus membrane with host cell membrane" +is_a: GO:0039663 ! membrane fusion involved in viral entry into host cell + +[Term] +id: GO:0019065 +name: receptor-mediated endocytosis of virus by host cell +namespace: biological_process +def: "Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell." [GOC:bf, GOC:jl, ISBN:0781702534] +synonym: "receptor mediated endocytosis by host of virus particle" EXACT [] +synonym: "receptor mediated endocytosis of virus by host" EXACT [] +synonym: "receptor mediated endocytosis of virus particle by host" EXACT [] +synonym: "receptor-mediated endocytosis of virus by host" EXACT [] +synonym: "viral entry into host cell via receptor-mediated endocytosis" RELATED [GOC:bf, GOC:jl] +synonym: "viral receptor mediated endocytosis" EXACT [] +synonym: "virus receptor-mediated endocytosis by host" EXACT [] +is_a: GO:0006898 ! receptor-mediated endocytosis +is_a: GO:0075509 ! endocytosis involved in viral entry into host cell +intersection_of: GO:0006898 ! receptor-mediated endocytosis +intersection_of: part_of GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0019066 +name: obsolete translocation of virus into host cell +namespace: biological_process +def: "OBSOLETE. The translocation of an entire virus particle across the host cell plasma membrane." [ISBN:0781702534] +comment: This term was made obsolete because it is ambiguous, and more specific terms have been created. +synonym: "translocation of virus into host cell" EXACT [] +synonym: "viral translocation" EXACT [] +is_obsolete: true +replaced_by: GO:0046718 + +[Term] +id: GO:0019068 +name: virion assembly +namespace: biological_process +alt_id: GO:0042963 +def: "A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed." [ISBN:0121585336] +synonym: "bacteriophage assembly" NARROW [GOC:bm] +synonym: "phage assembly" NARROW [GOC:bm] +synonym: "viral assembly" EXACT [] +synonym: "viral particle assembly" EXACT [] +synonym: "virion assembly and maintenance" EXACT [GOC:bf, GOC:jl] +synonym: "virion organization" EXACT [GOC:bf, GOC:jl] +synonym: "virus assembly" EXACT [GOC:dph, GOC:tb] +synonym: "virus particle assembly" EXACT [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0019069 +name: viral capsid assembly +namespace: biological_process +def: "The assembly of a virus capsid from its protein subunits." [ISBN:0781702534, UniProtKB-KW:KW-0118] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly + +[Term] +id: GO:0019070 +name: viral genome maturation +namespace: biological_process +def: "The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes." [GOC:pk, PMID:21490093] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly + +[Term] +id: GO:0019071 +name: viral DNA cleavage involved in viral genome maturation +namespace: biological_process +def: "The cleavage of viral DNA into singular functional units." [ISBN:0121585336] +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +relationship: part_of GO:0019070 ! viral genome maturation + +[Term] +id: GO:0019072 +name: viral genome packaging +namespace: biological_process +def: "The encapsulation of the viral genome within the capsid." [ISBN:0121585336] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly + +[Term] +id: GO:0019073 +name: viral DNA genome packaging +namespace: biological_process +def: "The packing of viral DNA into a capsid." [ISBN:0781702534] +is_a: GO:0019072 ! viral genome packaging + +[Term] +id: GO:0019074 +name: viral RNA genome packaging +namespace: biological_process +def: "The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid." [ISBN:0781718325] +is_a: GO:0019072 ! viral genome packaging + +[Term] +id: GO:0019075 +name: virus maturation +namespace: biological_process +def: "The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release." [ISBN:0781718325] +synonym: "bacteriophage maturation" NARROW [PMID:22308333] +synonym: "viral maturation" EXACT [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0019076 +name: viral release from host cell +namespace: biological_process +def: "The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane." [GOC:jl] +synonym: "release of virus from host" EXACT [] +synonym: "viral exit" EXACT [] +synonym: "viral release" EXACT [] +synonym: "viral shedding" EXACT [] +synonym: "virus exit from host cell" EXACT [GOC:bf, GOC:jl] +xref: VZ:1076 "Virus exit from host cell" +is_a: GO:0016032 ! viral process +is_a: GO:0035891 ! exit from host cell +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0019078 +name: obsolete lytic viral budding +namespace: biological_process +def: "OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment." [ISBN:0781702534] +comment: This term was made obsolete because it does not appear to correspond to a real biological process. +synonym: "lytic viral budding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0019079 +name: viral genome replication +namespace: biological_process +def: "Any process involved directly in viral genome replication, including viral nucleotide metabolism." [ISBN:0781702534] +synonym: "sigma virus replication" NARROW [] +synonym: "viral replication" BROAD [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0019080 +name: viral gene expression +namespace: biological_process +def: "A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation." [GOC:bf, GOC:jl, ISBN:0121585336] +synonym: "viral genome expression" EXACT [GOC:jl] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0019081 +name: viral translation +namespace: biological_process +def: "A process by which viral mRNA is translated into viral protein, using the host cellular machinery." [GOC:bf, GOC:jl, ISBN:0781702534] +synonym: "viral protein anabolism" EXACT [] +synonym: "viral protein biosynthesis" EXACT [] +synonym: "viral protein biosynthetic process" EXACT [ISBN:0781702534] +synonym: "viral protein formation" EXACT [] +synonym: "viral protein synthesis" EXACT [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019080 ! viral gene expression + +[Term] +id: GO:0019082 +name: viral protein processing +namespace: biological_process +def: "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein." [GOC:bf, GOC:jl, ISBN:0781702534] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019080 ! viral gene expression + +[Term] +id: GO:0019083 +name: viral transcription +namespace: biological_process +def: "The process by which a viral genome, or part of a viral genome, is transcribed within the host cell." [GOC:jl, ISBN:0781702534] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019080 ! viral gene expression + +[Term] +id: GO:0019084 +name: middle viral transcription +namespace: biological_process +def: "The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication." [GOC:bf, GOC:jl] +synonym: "(delayed) early viral mRNA transcription" RELATED [GOC:jh2] +is_a: GO:0019083 ! viral transcription + +[Term] +id: GO:0019085 +name: early viral transcription +namespace: biological_process +def: "The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell." [GOC:bf, GOC:jh2, GOC:jl] +synonym: "immediate early viral mRNA transcription" RELATED [] +is_a: GO:0019083 ! viral transcription + +[Term] +id: GO:0019086 +name: late viral transcription +namespace: biological_process +def: "The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins." [GOC:bf, GOC:jh2, GOC:jl] +synonym: "late viral mRNA transcription" RELATED [] +is_a: GO:0019083 ! viral transcription + +[Term] +id: GO:0019087 +name: transformation of host cell by virus +namespace: biological_process +alt_id: GO:0019088 +alt_id: GO:0020021 +def: "A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication." [ISBN:0781702534, PMID:11119620, PMID:18366075, PMID:24373315] +synonym: "host cell immortalization" EXACT [] +synonym: "host cell transformation" EXACT [] +synonym: "immortalization of host cell" EXACT [] +synonym: "immortalization of host cell by virus" RELATED [] +synonym: "transformation of host cell" EXACT [] +synonym: "viral immortalization" EXACT [] +synonym: "viral transformation" EXACT [] +synonym: "viral transformation of host cell" EXACT [] +xref: Wikipedia:Viral_transformation +is_a: GO:0019048 ! modulation by virus of host process + +[Term] +id: GO:0019089 +name: obsolete transmission of virus +namespace: biological_process +def: "OBSOLETE. The transfer of virions in order to create new infection." [ISBN:0781702534] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus. +synonym: "viral transmission" EXACT [] +is_obsolete: true + +[Term] +id: GO:0019090 +name: mitochondrial rRNA export from mitochondrion +namespace: biological_process +def: "The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol." [GOC:ai, PMID:28115039] +synonym: "export of mitochondrial rRNA" BROAD [] +synonym: "mitochondrial rRNA export" EXACT [] +synonym: "mitochondrial rRNA export from mitochondria" EXACT [] +synonym: "mitochondrial rRNA export out of mitochondrion" EXACT [] +synonym: "mitochondrial rRNA transport from mitochondrion" EXACT [] +synonym: "mitochondrial rRNA, mitochondrial export" EXACT [] +is_a: GO:0051029 ! rRNA transport +is_a: GO:1990542 ! mitochondrial transmembrane transport + +[Term] +id: GO:0019091 +name: mitochondrial lrRNA export from mitochondrion +namespace: biological_process +def: "The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol." [GOC:ai] +synonym: "export of mitochondrial lrRNA" BROAD [] +synonym: "mitochondrial lrRNA export" EXACT [] +synonym: "mitochondrial lrRNA export from mitochondria" EXACT [] +synonym: "mitochondrial lrRNA export out of mitochondrion" EXACT [] +synonym: "mitochondrial lrRNA transport from mitochondrion" EXACT [] +synonym: "mitochondrial lrRNA, mitochondrial export" EXACT [] +is_a: GO:0019090 ! mitochondrial rRNA export from mitochondrion + +[Term] +id: GO:0019092 +name: mitochondrial srRNA export from mitochondrion +namespace: biological_process +def: "The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol." [GOC:ai] +synonym: "export of mitochondrial srRNA" BROAD [] +synonym: "mitochondrial srRNA export" EXACT [] +synonym: "mitochondrial srRNA export from mitochondria" EXACT [] +synonym: "mitochondrial srRNA export out of mitochondrion" EXACT [] +synonym: "mitochondrial srRNA transport from mitochondrion" EXACT [] +synonym: "mitochondrial srRNA, mitochondrial export" EXACT [] +is_a: GO:0019090 ! mitochondrial rRNA export from mitochondrion + +[Term] +id: GO:0019093 +name: mitochondrial RNA localization +namespace: biological_process +def: "Any process in which mitochondrial RNA is transported to, or maintained in, a specific location." [GOC:ai] +synonym: "establishment and maintenance of mitochondrial RNA localization" EXACT [] +synonym: "mitochondrial RNA localisation" EXACT [GOC:mah] +synonym: "mtRNA localization" EXACT [] +is_a: GO:0006403 ! RNA localization +intersection_of: GO:0006403 ! RNA localization +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0019094 +name: pole plasm mRNA localization +namespace: biological_process +alt_id: GO:0048120 +def: "Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [GOC:ai] +synonym: "establishment and maintenance of mRNA localization in pole plasm" EXACT [] +synonym: "establishment and maintenance of pole plasm mRNA localization" EXACT [] +synonym: "oocyte pole plasm mRNA localization" EXACT [] +synonym: "pole granule RNA localization" BROAD [] +synonym: "pole plasm mRNA localisation" EXACT [GOC:mah] +is_a: GO:0007316 ! pole plasm RNA localization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0060811 ! intracellular mRNA localization involved in anterior/posterior axis specification + +[Term] +id: GO:0019095 +name: pole plasm mitochondrial rRNA localization +namespace: biological_process +alt_id: GO:0048117 +def: "Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [ISBN:0879694238] +synonym: "establishment and maintenance of mitochondrial rRNA localization in pole plasm" EXACT [] +synonym: "oocyte pole plasm mitochondrial rRNA localization" EXACT [] +synonym: "pole plasm mitochondrial rRNA localisation" EXACT [GOC:mah] +is_a: GO:0007316 ! pole plasm RNA localization +is_a: GO:0019093 ! mitochondrial RNA localization + +[Term] +id: GO:0019096 +name: pole plasm mitochondrial lrRNA localization +namespace: biological_process +alt_id: GO:0048118 +def: "Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [ISBN:0879694238] +synonym: "establishment and maintenance of mitochondrial lrRNA localization in pole plasm" EXACT [] +synonym: "oocyte pole plasm mitochondrial lrRNA localization" EXACT [] +synonym: "pole plasm mitochondrial lrRNA localisation" EXACT [GOC:mah] +is_a: GO:0019095 ! pole plasm mitochondrial rRNA localization + +[Term] +id: GO:0019097 +name: pole plasm mitochondrial srRNA localization +namespace: biological_process +alt_id: GO:0048119 +def: "Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [ISBN:0879694238] +synonym: "establishment and maintenance of mitochondrial localization in pole plasm" EXACT [] +synonym: "oocyte pole plasm mitochondrial srRNA localization" EXACT [] +synonym: "pole plasm mitochondrial srRNA localisation" EXACT [GOC:mah] +is_a: GO:0019095 ! pole plasm mitochondrial rRNA localization + +[Term] +id: GO:0019098 +name: reproductive behavior +namespace: biological_process +alt_id: GO:0033057 +alt_id: GO:0044704 +def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr] +subset: goslim_drosophila +synonym: "multicellular organism reproductive behavior" NARROW [] +synonym: "reproductive behavior in a multicellular organism" EXACT [] +synonym: "reproductive behaviour" EXACT [] +synonym: "single-organism reproductive behavior" RELATED [] +is_a: GO:0007610 ! behavior +is_a: GO:0048609 ! multicellular organismal reproductive process +intersection_of: GO:0007610 ! behavior +intersection_of: part_of GO:0000003 ! reproduction +created_by: jl +creation_date: 2012-09-19T16:01:37Z + +[Term] +id: GO:0019099 +name: female germ-line sex determination +namespace: biological_process +alt_id: GO:0007544 +def: "The determination of sex and sexual phenotype in a female organism's germ line." [GOC:mah] +synonym: "sex determination, female germ-line determination" EXACT [] +is_a: GO:0007542 ! primary sex determination, germ-line +is_a: GO:0018992 ! germ-line sex determination +is_a: GO:0030237 ! female sex determination + +[Term] +id: GO:0019100 +name: male germ-line sex determination +namespace: biological_process +def: "The determination of sex and sexual phenotype in a male organism's germ line." [GOC:mah] +is_a: GO:0007542 ! primary sex determination, germ-line +is_a: GO:0018992 ! germ-line sex determination +is_a: GO:0030238 ! male sex determination + +[Term] +id: GO:0019101 +name: female somatic sex determination +namespace: biological_process +def: "The determination of sex and sexual phenotypes in a female organism's soma." [GOC:mah] +is_a: GO:0018993 ! somatic sex determination +is_a: GO:0030237 ! female sex determination + +[Term] +id: GO:0019102 +name: male somatic sex determination +namespace: biological_process +def: "The determination of sex and sexual phenotypes in a male organism's soma." [GOC:mah] +is_a: GO:0018993 ! somatic sex determination +is_a: GO:0030238 ! male sex determination + +[Term] +id: GO:0019103 +name: pyrimidine nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate." [GOC:ai] +is_a: GO:0000166 ! nucleotide binding + +[Term] +id: GO:0019104 +name: DNA N-glycosylase activity +namespace: molecular_function +alt_id: GO:0008578 +def: "Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:11554296] +synonym: "DNA glycosylase activity" EXACT [] +synonym: "endonuclease VIII activity" RELATED [] +xref: EC:3.2.2 +xref: Reactome:R-HSA-110218 "Cleavage of uracil by TDG glycosylase" +xref: Reactome:R-HSA-110219 "Cleavage of thymine by TDG glycosylase" +xref: Reactome:R-HSA-110231 "Cleavage of uracil by MBD4 glycosylase" +xref: Reactome:R-HSA-110232 "Cleavage of thymine by MBD4 glycosylase" +xref: Reactome:R-HSA-110234 "Cleavage of ethenocytosine by TDG glycosylase" +xref: Reactome:R-HSA-110246 "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH" +xref: Reactome:R-HSA-110248 "Cleavage of 3-methyladenine by MPG glycosylase" +xref: Reactome:R-HSA-110250 "Cleavage of ethenoadenine by MPG glycosylase" +xref: Reactome:R-HSA-110251 "Cleavage of hypoxanthine by MPG glycosylase" +xref: Reactome:R-HSA-5220959 "TDG excises 5-formylcytosine" +xref: Reactome:R-HSA-5221061 "TDG excises 5-carboxylcytosine" +xref: Reactome:R-HSA-5649658 "NEIL1 cleaves DHU from damaged DNA" +xref: Reactome:R-HSA-5649664 "NEIL1 cleaves FapyG from damaged DNA" +xref: Reactome:R-HSA-5649673 "NEIL1 cleaves FapyA from damaged DNA" +xref: Reactome:R-HSA-5649681 "NEIL2 cleaves 5-OHU from damaged DNA" +xref: Reactome:R-HSA-9629149 "NEIL1 cleaves thymine glycol from damaged DNA" +xref: Reactome:R-HSA-9629216 "NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA" +xref: Reactome:R-HSA-9629470 "NEIL3 cleaves 5-guanidinohydantoin" +xref: Reactome:R-HSA-9629483 "NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA" +xref: Reactome:R-HSA-9629492 "NEIL3 cleaves spiroiminodihydantoin" +xref: Reactome:R-HSA-9629497 "NEIL3 cleaves thymine glycol from telomeric DNA" +xref: Reactome:R-HSA-9629499 "NEIL3 cleaves thymine glycol" +xref: Reactome:R-HSA-9635996 "NEIL3 resolves psoralen-induced ICLs" +xref: Reactome:R-HSA-9636008 "NEIL3 resolves abasic site-induced ICLs" +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0019105 +name: N-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016409 ! palmitoyltransferase activity +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0019107 +name: myristoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule." [GOC:ai] +xref: Reactome:R-HSA-141367 "Myristoylation of tBID by NMT1" +xref: Reactome:R-HSA-162914 "Myristoylation of Nef" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0019108 +name: aryl-aldehyde dehydrogenase (NAD) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+." [EC:1.2.1.29] +synonym: "aryl-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.29] +xref: EC:1.2.1.29 +xref: MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN +xref: UM-BBD_reactionID:r0394 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0019111 +name: phenanthrol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate." [EC:2.8.2.-] +synonym: "phenanthrol sulphotransferase activity" EXACT [] +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0019112 +name: phenanthrol glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O." [GOC:ai] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0019113 +name: limonene monooxygenase activity +namespace: molecular_function +def: "Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene." [GOC:mah] +xref: EC:1.14.13 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0019114 +name: catechol dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: catechol + O2 = a muconate." [GOC:mah, MetaCyc:CATECHOL-12-DIOXYGENASE-RXN, MetaCyc:CATECHOL-23-DIOXYGENASE-RXN] +xref: EC:1.13.11 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0019115 +name: benzaldehyde dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+." [EC:1.2.1.28, EC:1.2.1.7] +xref: EC:1.2.1 +is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0019116 +name: hydroxy-nicotine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide." [GOC:jl, http://umbbd.ahc.umn.edu/] +xref: EC:1.5.3.6 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0019117 +name: dihydroxyfluorene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid." [GOC:mah, UM-BBD_reactionID:r0415, UM-BBD_reactionID:r0422] +xref: EC:1.13.11 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0019118 +name: phenanthrene-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene." [GOC:mah, UM-BBD_reactionID:r0535, UM-BBD_reactionID:r0536] +xref: EC:3.3.2 +is_a: GO:0004301 ! epoxide hydrolase activity + +[Term] +id: GO:0019119 +name: phenanthrene-9,10-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene." [GOC:mah, UM-BBD_reactionID:r0496, UM-BBD_reactionID:r0560] +is_a: GO:0019118 ! phenanthrene-epoxide hydrolase activity + +[Term] +id: GO:0019120 +name: hydrolase activity, acting on acid halide bonds, in C-halide compounds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage." [ISBN:0198506732] +xref: EC:3.8.1 +xref: Reactome:R-HSA-9011595 "GSTZ1 dimer dehalogenates DCA to glyoxylate" +is_a: GO:0016824 ! hydrolase activity, acting on acid halide bonds + +[Term] +id: GO:0019121 +name: peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine +namespace: biological_process +def: "The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan." [RESID:AA0218] +xref: RESID:AA0218 +is_a: GO:0018104 ! peptidoglycan-protein cross-linking +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0019122 +name: peptidyl-D-alanine racemization +namespace: biological_process +def: "The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine." [RESID:AA0191] +comment: See also the biological process terms 'peptidyl-D-alanine racemization, direct ; GO:0019916' and 'peptidyl-D-alanine racemization via peptidyl-L-serine ; GO:0019917'. +synonym: "alanine racemization" BROAD [] +xref: RESID:AA0191 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0019123 +name: peptidyl-methionine racemization +namespace: biological_process +alt_id: GO:0018087 +alt_id: GO:0018369 +def: "The racemization of peptidyl-methionine." [RESID:AA0193] +xref: RESID:AA0193 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019124 +name: peptidyl-isoleucine racemization +namespace: biological_process +alt_id: GO:0018088 +alt_id: GO:0018370 +def: "The racemization of peptidyl-isoleucine." [RESID:AA0192] +xref: RESID:AA0192 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019125 +name: peptidyl-phenylalanine racemization +namespace: biological_process +alt_id: GO:0018089 +alt_id: GO:0018371 +def: "The racemization of peptidyl-phenylalanine." [RESID:AA0194] +xref: RESID:AA0194 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019126 +name: peptidyl-serine racemization +namespace: biological_process +alt_id: GO:0018090 +alt_id: GO:0018372 +def: "The racemization of peptidyl-serine." [RESID:AA0195] +xref: RESID:AA0195 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019128 +name: peptidyl-tryptophan racemization +namespace: biological_process +alt_id: GO:0018092 +alt_id: GO:0018374 +def: "The racemization of peptidyl-tryptophan." [RESID:AA0198] +xref: RESID:AA0198 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019129 +name: peptidyl-leucine racemization +namespace: biological_process +alt_id: GO:0018093 +alt_id: GO:0018375 +def: "The racemization of peptidyl-leucine." [RESID:AA0197] +xref: RESID:AA0197 +is_a: GO:0018085 ! peptidyl-L-amino acid racemization + +[Term] +id: GO:0019131 +name: obsolete tripeptidyl-peptidase I activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH." [EC:3.4.14.9] +comment: This term was made obsolete because it represents a gene product. +synonym: "tripeptidyl aminopeptidase activity" BROAD [EC:3.4.14.9] +synonym: "tripeptidyl peptidase activity" BROAD [EC:3.4.14.9] +synonym: "tripeptidyl-peptidase I activity" EXACT [] +xref: EC:3.4.14.9 +xref: MetaCyc:3.4.14.9-RXN +is_obsolete: true +replaced_by: GO:0008240 + +[Term] +id: GO:0019132 +name: obsolete C-terminal processing peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala." [EC:3.4.21.102] +comment: This term was made obsolete because it represents a gene product. +synonym: "C-terminal processing peptidase activity" EXACT [] +synonym: "CtpA gene product (Synechocystis sp.)" RELATED [EC:3.4.21.102] +synonym: "photosystem II D1 protein processing peptidase" NARROW [EC:3.4.21.102] +synonym: "protease Re" RELATED [EC:3.4.21.102] +synonym: "tail-specific protease activity" EXACT [EC:3.4.21.102] +synonym: "Tsp protease" NARROW [EC:3.4.21.102] +xref: EC:3.4.21.102 +xref: MetaCyc:3.4.21.102-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0019133 +name: choline monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O." [EC:1.14.15.7] +synonym: "choline,reduced-ferredoxin:oxygen oxidoreductase activity" EXACT [EC:1.14.15.7] +xref: EC:1.14.15.7 +xref: MetaCyc:RXN1F-357 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0019134 +name: glucosamine-1-phosphate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+)." [EC:2.3.1.157, RHEA:13725] +synonym: "acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.157] +synonym: "acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.157] +xref: EC:2.3.1.157 +xref: KEGG_REACTION:R05332 +xref: MetaCyc:2.3.1.157-RXN +xref: RHEA:13725 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0019135 +name: deoxyhypusine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O." [EC:1.14.99.29] +synonym: "deoxyhypusine dioxygenase activity" EXACT [EC:1.14.99.29] +synonym: "deoxyhypusine hydroxylase activity" EXACT [] +synonym: "deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.99.29] +synonym: "DOHH activity" EXACT [EC:1.14.99.29] +xref: EC:1.14.99.29 +xref: MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-204662 "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A" +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0019136 +name: deoxynucleoside kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate." [EC:2.7.1.145] +synonym: "ATP:deoxynucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.145] +synonym: "D. melanogaster deoxynucleoside kinase activity" EXACT [EC:2.7.1.145] +synonym: "Dm-dNK" RELATED [EC:2.7.1.145] +synonym: "ms-dNK" RELATED [EC:2.7.1.145] +synonym: "Ms-dNK activity" RELATED [EC:2.7.1.145] +synonym: "multifunctional deoxynucleoside kinase activity" RELATED [EC:2.7.1.145] +synonym: "multispecific deoxynucleoside kinase activity" RELATED [EC:2.7.1.145] +synonym: "multisubstrate deoxyribonucleoside kinase activity" RELATED [EC:2.7.1.145] +xref: EC:2.7.1.145 +xref: MetaCyc:2.7.1.145-RXN +is_a: GO:0019206 ! nucleoside kinase activity +relationship: part_of GO:0009157 ! deoxyribonucleoside monophosphate biosynthetic process + +[Term] +id: GO:0019137 +name: thioglucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar." [EC:3.2.1.147] +synonym: "myrosinase activity" EXACT [] +synonym: "sinigrase activity" EXACT [] +synonym: "sinigrinase activity" EXACT [] +synonym: "thioglucoside glucohydrolase activity" EXACT [] +xref: EC:3.2.1.147 +xref: MetaCyc:RXN-9946 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0019139 +name: cytokinin dehydrogenase activity +namespace: molecular_function +alt_id: GO:0046420 +def: "Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor." [EC:1.5.99.12] +synonym: "6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.12] +synonym: "cytokinin oxidase activity" RELATED [] +synonym: "N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.12] +synonym: "N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.12] +xref: EC:1.5.99.12 +xref: MetaCyc:1.5.99.12-RXN +xref: MetaCyc:PWY-2841 +xref: RHEA:13625 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0019140 +name: inositol 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate." [EC:2.7.1.64] +synonym: "ATP:myo-inositol 1-phosphotransferase activity" EXACT [EC:2.7.1.64] +synonym: "inositol 1-kinase activity" RELATED [EC:2.7.1.64] +synonym: "inositol-1-kinase (phosphorylating)" EXACT [EC:2.7.1.64] +synonym: "myo-inositol 1-kinase activity" RELATED [EC:2.7.1.64] +synonym: "myo-inositol 3-kinase activity" EXACT [] +synonym: "myoinositol kinase activity" BROAD [EC:2.7.1.64] +xref: EC:2.7.1.64 +xref: MetaCyc:MYO-INOSITOL-1-KINASE-RXN +xref: RHEA:21804 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0019141 +name: 2-dehydropantolactone reductase (B-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+." [EC:1.1.1.214] +synonym: "(R)-pantolactone:NADP+ oxidoreductase (B-specific)" EXACT [EC:1.1.1.214] +synonym: "2-dehydropantoyl-lactone reductase (B-specific) activity" EXACT [] +synonym: "2-ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.214] +synonym: "2-oxopantoyl lactone reductase" BROAD [EC:1.1.1.214] +synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.214] +xref: EC:1.1.1.214 +xref: MetaCyc:DEHYDROPANTLACRED-RXN +is_a: GO:0036441 ! 2-dehydropantolactone reductase activity + +[Term] +id: GO:0019142 +name: 2-hydroxyglutarate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+)." [EC:2.3.3.11, RHEA:19185] +comment: Note that this function was formerly EC:4.1.3.9. +synonym: "2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity" EXACT [EC:2.3.3.11] +synonym: "2-hydroxyglutaratic synthetase activity" EXACT [EC:2.3.3.11] +synonym: "2-hydroxyglutaric synthetase activity" EXACT [EC:2.3.3.11] +synonym: "alpha-hydroxyglutarate synthase activity" EXACT [EC:2.3.3.11] +synonym: "hydroxyglutarate synthase activity" EXACT [EC:2.3.3.11] +synonym: "propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)" EXACT [EC:2.3.3.11] +xref: EC:2.3.3.11 +xref: KEGG_REACTION:R00932 +xref: MetaCyc:HYDGLUTSYN-RXN +xref: RHEA:19185 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0019143 +name: 3-deoxy-manno-octulosonate-8-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate." [EC:3.1.3.45, RHEA:11500] +synonym: "3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity" EXACT [EC:3.1.3.45] +xref: EC:3.1.3.45 +xref: KEGG_REACTION:R03350 +xref: MetaCyc:KDO-8PPHOSPHAT-RXN +xref: RHEA:11500 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0019144 +name: ADP-sugar diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate." [EC:3.6.1.21] +synonym: "adenosine diphosphosugar pyrophosphatase activity" EXACT [EC:3.6.1.21] +synonym: "ADP-sugar pyrophosphatase activity" EXACT [EC:3.6.1.21] +synonym: "ADP-sugar sugarphosphohydrolase activity" EXACT [EC:3.6.1.21] +synonym: "ADPsugar pyrophosphatase activity" EXACT [EC:3.6.1.21] +synonym: "nucleoside diphosphate-sugar hydrolase activity" BROAD [GOC:vw] +xref: EC:3.6.1.21 +xref: MetaCyc:ADPSUGPPHOSPHAT-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0019145 +name: aminobutyraldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+." [EC:1.2.1.19] +synonym: "4-aminobutanal dehydrogenase activity" EXACT [EC:1.2.1.19] +synonym: "4-aminobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.19] +synonym: "4-aminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.19] +synonym: "ABAL dehydrogenase activity" EXACT [EC:1.2.1.19] +synonym: "gamma-aminobutyraldehyde dehydroganase activity" EXACT [EC:1.2.1.19] +xref: EC:1.2.1.19 +xref: MetaCyc:AMINOBUTDEHYDROG-RXN +xref: RHEA:19105 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0019146 +name: arabinose-5-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+)." [EC:5.3.1.13, RHEA:23104] +synonym: "arabinose phosphate isomerase activity" EXACT [EC:5.3.1.13] +synonym: "D-arabinose-5-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.13] +synonym: "D-arabinose-5-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.13] +synonym: "phosphoarabinoisomerase activity" EXACT [EC:5.3.1.13] +xref: EC:5.3.1.13 +xref: KEGG_REACTION:R01530 +xref: MetaCyc:DARAB5PISOM-RXN +xref: RHEA:23104 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0019147 +name: (R)-aminopropanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH." [EC:1.1.1.75, RHEA:16517] +synonym: "(R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.75] +synonym: "1-aminopropan-2-ol-dehydrogenase activity" EXACT [EC:1.1.1.75] +synonym: "1-aminopropan-2-ol-NAD+ dehydrogenase activity" EXACT [EC:1.1.1.75] +synonym: "DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity" EXACT [EC:1.1.1.75] +synonym: "L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity" EXACT [EC:1.1.1.75] +synonym: "L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.75] +synonym: "L-aminopropanol dehydrogenase activity" EXACT [] +xref: EC:1.1.1.75 +xref: KEGG_REACTION:R03759 +xref: MetaCyc:AMINOPROPDEHYDROG-RXN +xref: RHEA:16517 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019148 +name: D-cysteine desulfhydrase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate." [EC:4.4.1.15] +synonym: "D-cysteine lyase activity" EXACT [EC:4.4.1.15] +synonym: "D-cysteine sulfide-lyase (deaminating)" EXACT [EC:4.4.1.15] +synonym: "D-cysteine sulfide-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.15] +xref: EC:4.4.1.15 +xref: MetaCyc:DCYSDESULF-RXN +xref: RHEA:11268 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0019149 +name: 3-chloro-D-alanine dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3." [EC:4.5.1.2] +synonym: "3-chloro-D-alanine chloride-lyase (deaminating)" EXACT [EC:4.5.1.2] +synonym: "3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.5.1.2] +synonym: "beta-chloro-D-alanine dehydrochlorinase activity" EXACT [EC:4.5.1.2] +xref: EC:4.5.1.2 +xref: MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN +xref: RHEA:18873 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0019150 +name: D-ribulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate." [EC:2.7.1.47] +synonym: "ATP:D-ribulose 5-phosphotransferase activity" EXACT [EC:2.7.1.47] +synonym: "D-ribulokinase (phosphorylating)" EXACT [EC:2.7.1.47] +xref: EC:2.7.1.47 +xref: MetaCyc:D-RIBULOKIN-RXN +xref: RHEA:17601 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0019151 +name: galactose 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+." [EC:1.1.1.48] +synonym: "beta-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] +synonym: "D-galactose 1-dehydrogenase activity" EXACT [] +synonym: "D-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] +synonym: "D-galactose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.48] +synonym: "NAD-dependent D-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] +xref: EC:1.1.1.48 +xref: MetaCyc:GALACTODEHYDROG-RXN +xref: RHEA:21296 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019152 +name: acetoin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+." [EC:1.1.1.303, EC:1.1.1.304, MetaCyc:ACETOINDEHYDROG-RXN] +synonym: "diacetyl reductase activity" EXACT [] +xref: EC:1.1.1.303 +xref: EC:1.1.1.304 +xref: KEGG_REACTION:R02343 +xref: MetaCyc:ACETOINDEHYDROG-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019153 +name: protein-disulfide reductase (glutathione) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol." [EC:1.8.4.2] +synonym: "glutaredoxin reductase" RELATED [] +synonym: "glutathione--insulin transhydrogenase activity" EXACT [EC:1.8.4.2] +synonym: "glutathione-insulin transhydrogenase activity" EXACT [] +synonym: "glutathione-protein disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] +synonym: "glutathione:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] +synonym: "GSH-insulin transhydrogenase activity" EXACT [EC:1.8.4.2] +synonym: "insulin reductase activity" EXACT [EC:1.8.4.2] +synonym: "protein disulfide reductase (glutathione)" EXACT [EC:1.8.4.2] +synonym: "protein disulfide transhydrogenase activity" EXACT [EC:1.8.4.2] +synonym: "protein-disulfide interchange enzyme" RELATED [EC:1.8.4.2] +synonym: "protein-disulfide isomerase/oxidoreductase activity" EXACT [EC:1.8.4.2] +synonym: "protein-disulphide reductase (glutathione) activity" EXACT [] +synonym: "reductase, protein disulfide (glutathione)" EXACT [EC:1.8.4.2] +synonym: "thiol-protein disulphide oxidoreductase activity" EXACT [EC:1.8.4.2] +synonym: "thiol:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] +xref: EC:1.8.4.2 +xref: MetaCyc:PRODISULFREDUCT-RXN +xref: RHEA:21064 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0019154 +name: glycolate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate." [EC:1.1.99.14, RHEA:21264] +synonym: "glycolate oxidoreductase activity" EXACT [EC:1.1.99.14] +synonym: "glycolate:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.14] +synonym: "glycolate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.14] +synonym: "glycolic acid dehydrogenase activity" EXACT [EC:1.1.99.14] +xref: EC:1.1.99.14 +xref: KEGG_REACTION:R00476 +xref: MetaCyc:GLYCOLATEDEHYDRO-RXN +xref: RHEA:21264 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0019155 +name: 3-(imidazol-5-yl)lactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+." [EC:1.1.1.111] +synonym: "(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.111] +synonym: "imidazol-5-yl lactate dehydrogenase activity" EXACT [EC:1.1.1.111] +xref: EC:1.1.1.111 +xref: MetaCyc:IMILACTDEHYDROG-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019156 +name: isoamylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins." [EC:3.2.1.68] +synonym: "debranching enzyme activity" BROAD [EC:3.2.1.68] +synonym: "glycogen alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.68] +xref: EC:3.2.1.68 +xref: MetaCyc:3.2.1.68-RXN +xref: MetaCyc:RXN-12280 +xref: MetaCyc:RXN-14380 +is_a: GO:0004133 ! glycogen debranching enzyme activity +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0019157 +name: malate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate." [RHEA:10515] +synonym: "(S)-malate:oxygen oxidoreductase activity" EXACT [] +synonym: "FAD-dependent malate oxidase activity" EXACT [] +synonym: "malic dehydrogenase II" RELATED [] +synonym: "malic oxidase activity" EXACT [] +xref: KEGG_REACTION:R00360 +xref: MetaCyc:MALOX-RXN +xref: RHEA:10515 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0019158 +name: mannokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate." [EC:2.7.1.7] +synonym: "ATP:D-mannose 6-phosphotransferase activity" EXACT [EC:2.7.1.7] +synonym: "D-fructose (D-mannose) kinase activity" EXACT [EC:2.7.1.7] +synonym: "mannokinase (phosphorylating)" EXACT [EC:2.7.1.7] +xref: EC:2.7.1.7 +xref: MetaCyc:MANNKIN-RXN +xref: RHEA:11028 +is_a: GO:0004396 ! hexokinase activity + +[Term] +id: GO:0019159 +name: nicotinamide-nucleotide amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3." [EC:3.5.1.42] +synonym: "nicotinamide mononucleotide amidohydrolase activity" EXACT [EC:3.5.1.42] +synonym: "nicotinamide mononucleotide deamidase activity" EXACT [EC:3.5.1.42] +synonym: "nicotinamide-D-ribonucleotide amidohydrolase activity" EXACT [EC:3.5.1.42] +synonym: "NMN amidohydrolase" NARROW [] +synonym: "NMN deamidase activity" EXACT [EC:3.5.1.42] +xref: EC:3.5.1.42 +xref: MetaCyc:NMNAMIDOHYDRO-RXN +xref: RHEA:12400 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0019160 +name: NMN nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide." [EC:3.2.2.14, RHEA:23140] +synonym: "nicotinamide mononucleotidase activity" EXACT [EC:3.2.2.14] +synonym: "nicotinamide mononucleotide nucleosidase activity" EXACT [EC:3.2.2.14] +synonym: "nicotinamide-nucleotide phosphoribohydrolase activity" EXACT [EC:3.2.2.14] +synonym: "NMN glycohydrolase activity" EXACT [EC:3.2.2.14] +synonym: "NMNase activity" EXACT [EC:3.2.2.14] +synonym: "NMNGhase activity" EXACT [EC:3.2.2.14] +xref: EC:3.2.2.14 +xref: KEGG_REACTION:R01270 +xref: MetaCyc:NMNNUCLEOSID-RXN +xref: RHEA:23140 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0019161 +name: diamine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate." [EC:2.6.1.29] +synonym: "amine transaminase activity" EXACT [EC:2.6.1.29] +synonym: "amine-ketoacid transaminase activity" EXACT [EC:2.6.1.29] +synonym: "diamine aminotransferase activity" EXACT [] +synonym: "diamine-ketoglutaric transaminase activity" EXACT [EC:2.6.1.29] +synonym: "diamine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.29] +xref: EC:2.6.1.29 +xref: MetaCyc:DIAMTRANSAM-RXN +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0019162 +name: pyridoxamine-oxaloacetate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal." [EC:2.6.1.31, RHEA:10844] +synonym: "pyridoxamine--oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.31] +synonym: "pyridoxamine-oxaloacetate aminotransferase activity" EXACT [] +synonym: "pyridoxamine:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.31] +xref: EC:2.6.1.31 +xref: KEGG_REACTION:R01713 +xref: MetaCyc:PYROXALTRANSAM-RXN +xref: RHEA:10844 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0019163 +name: pyridoxamine-phosphate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate." [EC:2.6.1.54] +synonym: "pyridoxamine 5'-phosphate transaminase activity" EXACT [EC:2.6.1.54] +synonym: "pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.54] +synonym: "pyridoxamine phosphate aminotransferase activity" EXACT [EC:2.6.1.54] +synonym: "pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)" EXACT [EC:2.6.1.54] +synonym: "pyridoxamine-phosphate aminotransferase activity" EXACT [] +xref: EC:2.6.1.54 +xref: MetaCyc:PYRDAMPTRANS-RXN +xref: RHEA:15877 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0019164 +name: pyruvate synthase activity +namespace: molecular_function +alt_id: GO:0018696 +def: "Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+." [KEGG_REACTION:R01196] +synonym: "PFOR" EXACT [] +synonym: "pyruvate oxidoreductase activity" EXACT [EC:1.2.7.1] +synonym: "pyruvate synthetase activity" EXACT [EC:1.2.7.1] +synonym: "pyruvate-ferredoxin reductase activity" EXACT [] +synonym: "pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.7.1] +synonym: "pyruvate:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.1] +synonym: "pyruvic-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.1] +xref: EC:1.2.7.1 +xref: KEGG_REACTION:R01196 +xref: MetaCyc:PYRUFLAVREDUCT-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor +relationship: part_of GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate + +[Term] +id: GO:0019165 +name: thiamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate." [EC:2.7.1.89, RHEA:12012] +synonym: "ATP:thiamin phosphotransferase activity" EXACT [EC:2.7.1.89] +synonym: "ATP:thiamine phosphotransferase activity" EXACT [EC:2.7.1.89] +synonym: "thiamin kinase (phosphorylating)" EXACT [EC:2.7.1.89] +synonym: "thiamin kinase activity" EXACT [EC:2.7.1.89] +synonym: "thiamin phosphokinase activity" EXACT [EC:2.7.1.89] +xref: EC:2.7.1.89 +xref: KEGG_REACTION:R02134 +xref: MetaCyc:THIKIN-RXN +xref: RHEA:12012 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0019166 +name: trans-2-enoyl-CoA reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+." [EC:1.3.1.38] +synonym: "acyl-CoA:NADP+ trans-2-oxidoreductase activity" EXACT [EC:1.3.1.38] +synonym: "NADPH-dependent trans-2-enoyl-CoA reductase activity" EXACT [EC:1.3.1.38] +synonym: "reductase, trans-enoyl coenzyme A" EXACT [EC:1.3.1.38] +xref: EC:1.3.1.38 +xref: MetaCyc:TRANSENOYLCOARED-RXN +xref: Reactome:R-HSA-6786720 "DECR2 reduces LCtE-CoA to t3enoyl-CoA" +xref: Reactome:R-HSA-6809810 "PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA" +xref: Reactome:R-HSA-8952873 "MECR dimer reduces tdec2-CoA to DEC-CoA" +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019168 +name: 2-octaprenylphenol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O." [MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN] +xref: MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0019170 +name: methylglyoxal reductase (NADH-dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+." [EC:1.1.1.78] +synonym: "(R)-lactaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.78] +synonym: "D-lactaldehyde dehydrogenase activity" EXACT [] +synonym: "methylglyoxal reductase activity" EXACT [] +xref: EC:1.1.1.78 +xref: MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN +xref: RHEA:24528 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0019171 +name: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein]." [MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN] +synonym: "3-hydroxyacyl-[acyl-carrier protein] dehydratase activity" EXACT [] +synonym: "3-hydroxyacyl-ACP dehydratase activity" EXACT [] +xref: EC:4.2.1.59 +xref: MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN +xref: RHEA:13097 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0019172 +name: glyoxalase III activity +namespace: molecular_function +def: "Catalysis of the reaction: methylglyoxal + H2O = D-lactate." [EC:4.2.1.130, GOC:mcc, http://www.brenda-enzymes.org/php/result_flat.php4?ecno=4.2.1.130, MetaCyc:GLYOXIII-RXN, PMID:21696459, PMID:7848303, RHEA:27754] +comment: Note that this term was reinstated from obsolete. Also note that this enzymatic activity converts methylglyoxal to D-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalyzed by EC:4.4.1.5 (lactoylglutathione lyase) and EC:3.1.2.6 (hydroxyacylglutathione hydrolase). +synonym: "(R)-lactate hydro-lyase" EXACT [] +synonym: "D-lactate dehydratase" EXACT [] +synonym: "glutathione-independent glyoxalase activity" RELATED [] +xref: MetaCyc:GLYOXIII-RXN +xref: RHEA:27754 +is_a: GO:0016836 ! hydro-lyase activity +relationship: part_of GO:0019249 ! lactate biosynthetic process +relationship: part_of GO:0061727 ! methylglyoxal catabolic process to lactate + +[Term] +id: GO:0019174 +name: tetrahydrothiophene 1-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor." [MetaCyc:THTOREDUCT-RXN] +xref: MetaCyc:THTOREDUCT-RXN +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0019176 +name: dihydroneopterin monophosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate." [MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN] +synonym: "dihydroneopterin monophosphate dephosphorylase activity" EXACT [] +xref: MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0019177 +name: dihydroneopterin triphosphate pyrophosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate." [MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN] +xref: MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0019178 +name: NADP phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate." [MetaCyc:NADPPHOSPHAT-RXN] +xref: MetaCyc:NADPPHOSPHAT-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0019179 +name: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate." [EC:2.6.1.33] +synonym: "dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity" EXACT [] +synonym: "dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.33] +synonym: "TDP-4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] +synonym: "TDP-4-oxo-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] +synonym: "thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity" EXACT [EC:2.6.1.33] +synonym: "thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity" EXACT [EC:2.6.1.33] +synonym: "thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] +synonym: "thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity" EXACT [EC:2.6.1.33] +xref: EC:2.6.1.33 +xref: MetaCyc:2.6.1.33-RXN +xref: RHEA:19085 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0019180 +name: dTDP-4-amino-4,6-dideoxygalactose transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose." [EC:2.6.1.59, RHEA:10368] +synonym: "dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.59] +synonym: "dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity" EXACT [EC:2.6.1.59] +synonym: "dTDP-fucosamine aminotransferase activity" EXACT [] +synonym: "thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.59] +synonym: "thymidine diphosphoaminodideoxygalactose aminotransferase activity" EXACT [EC:2.6.1.59] +xref: EC:2.6.1.59 +xref: KEGG_REACTION:R04438 +xref: MetaCyc:2.6.1.59-RXN +xref: RHEA:10368 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0019181 +name: halohydrin hydrogen-halide-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide." [PMID:8017917] +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0019182 +name: histamine-gated chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0022835 ! transmitter-gated channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity + +[Term] +id: GO:0019183 +name: histamine-gated chloride channel complex +namespace: cellular_component +def: "A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts." [GOC:mah] +is_a: GO:0034707 ! chloride channel complex +is_a: GO:0098878 ! neurotransmitter receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0019184 +name: nonribosomal peptide biosynthetic process +namespace: biological_process +def: "The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione." [ISBN:0198506732] +synonym: "non-ribosomal peptide biosynthesis" EXACT [] +synonym: "non-ribosomal peptide biosynthetic process" EXACT [] +synonym: "non-ribosomal peptide formation" EXACT [] +synonym: "non-ribosomal peptide synthesis" EXACT [] +synonym: "nonribosomal peptide anabolism" EXACT [] +synonym: "nonribosomal peptide biosynthesis" EXACT [] +synonym: "nonribosomal peptide formation" EXACT [] +synonym: "nonribosomal peptide synthesis" EXACT [] +synonym: "nonribosomal peptide synthetase" RELATED [] +is_a: GO:0043043 ! peptide biosynthetic process + +[Term] +id: GO:0019185 +name: snRNA-activating protein complex +namespace: cellular_component +def: "A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters." [PMID:7715707, PMID:9003788] +synonym: "SNAPc" EXACT [] +is_a: GO:0005667 ! transcription regulator complex + +[Term] +id: GO:0019186 +name: acyl-CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule." [GOC:mah] +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0019187 +name: beta-1,4-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage." [GOC:mcc, PMID:8166646] +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0019191 +name: cellobiose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0019190 +def: "Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "cellobiose permease activity" EXACT [] +is_a: GO:0015154 ! disaccharide transmembrane transporter activity +relationship: part_of GO:0019533 ! cellobiose transport + +[Term] +id: GO:0019194 +name: sorbose transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0019193 +def: "Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "sorbose porter activity" EXACT [] +is_a: GO:0015149 ! hexose transmembrane transporter activity + +[Term] +id: GO:0019196 +name: galactosamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0019195 +def: "Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +synonym: "galactosamine porter activity" EXACT [] +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity + +[Term] +id: GO:0019197 +name: phosphoenolpyruvate-dependent sugar phosphotransferase complex +namespace: cellular_component +def: "Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system)." [GOC:ma] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0019198 +name: transmembrane receptor protein phosphatase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate." [GOC:hjd] +xref: EC:3.1.3 +is_a: GO:0004721 ! phosphoprotein phosphatase activity +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0019199 +name: transmembrane receptor protein kinase activity +namespace: molecular_function +def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP." [GOC:mah] +xref: Reactome:R-HSA-8983059 "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex" +xref: Reactome:R-HSA-8983063 "JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated" +is_a: GO:0004672 ! protein kinase activity +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0019200 +name: carbohydrate kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule." [GOC:jl] +xref: Reactome:R-HSA-8931653 "POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1" +is_a: GO:0016301 ! kinase activity +relationship: part_of GO:0046835 ! carbohydrate phosphorylation + +[Term] +id: GO:0019202 +name: amino acid kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate." [GOC:jl] +is_a: GO:0016301 ! kinase activity + +[Term] +id: GO:0019203 +name: carbohydrate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate." [GOC:mah] +xref: Reactome:R-HSA-3781011 "EPM2A dimer dephosphorylates phosphoglycogen-GYG2" +xref: Reactome:R-HSA-3781018 "EPM2A dimer dephosphorylates phosphoglycogen-GYG1" +xref: Reactome:R-HSA-3791349 "Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease)" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0019204 +name: obsolete nucleotide phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate." [GOC:mah] +comment: This term was defined to cover phosphatase activity against polynucleotides, but had subclasses and annotations for phosphatase activity against free nucleotides. It has therefore been split. Use GO:0098519 (nucleotide phosphatase activity, acting against free nucleotides) or GO:0098518 (polynucleotide phosphatase activity). +synonym: "nucleotide phosphatase activity" EXACT [] +is_obsolete: true +consider: GO:0098518 +consider: GO:0098519 + +[Term] +id: GO:0019205 +name: nucleobase-containing compound kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate." [GOC:jl] +synonym: "nucleobase, nucleoside, nucleotide kinase activity" RELATED [GOC:dph, GOC:tb] +is_a: GO:0016301 ! kinase activity + +[Term] +id: GO:0019206 +name: nucleoside kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate." [GOC:ai] +xref: Reactome:R-HSA-109671 "deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)" +xref: Reactome:R-HSA-109759 "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]" +xref: Reactome:R-HSA-109903 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]" +xref: Reactome:R-HSA-110137 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP" +xref: Reactome:R-HSA-110138 "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs" +xref: Reactome:R-HSA-73598 "(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)" +xref: Reactome:R-HSA-73599 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]" +xref: Reactome:R-HSA-73632 "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]" +xref: Reactome:R-HSA-74207 "dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)" +is_a: GO:0019205 ! nucleobase-containing compound kinase activity +relationship: part_of GO:0009165 ! nucleotide biosynthetic process + +[Term] +id: GO:0019207 +name: kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:ai] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0043549 ! regulation of kinase activity + +[Term] +id: GO:0019208 +name: phosphatase regulator activity +namespace: molecular_function +def: "Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0019902 ! phosphatase binding +relationship: regulates GO:0016791 ! phosphatase activity + +[Term] +id: GO:0019209 +name: kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:ai] +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0019207 ! kinase regulator activity +relationship: part_of GO:0033674 ! positive regulation of kinase activity + +[Term] +id: GO:0019210 +name: kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0019207 ! kinase regulator activity +relationship: part_of GO:0033673 ! negative regulation of kinase activity + +[Term] +id: GO:0019211 +name: phosphatase activator activity +namespace: molecular_function +def: "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0019208 ! phosphatase regulator activity + +[Term] +id: GO:0019212 +name: phosphatase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0019208 ! phosphatase regulator activity + +[Term] +id: GO:0019213 +name: deacetylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule." [GOC:jl] +subset: goslim_pir +xref: Reactome:R-HSA-5689000 "AADAC deacetylates PHEN" +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0019214 +name: obsolete surfactant activity +namespace: molecular_function +def: "OBSOLETE. The action of reducing the surface tension of a liquid." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it represents involvement in a process. +synonym: "surfactant activity" EXACT [] +is_obsolete: true +consider: GO:0050828 + +[Term] +id: GO:0019215 +name: intermediate filament binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space." [ISBN:0198506732] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0019216 +name: regulation of lipid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] +synonym: "regulation of lipid metabolism" EXACT [] +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006629 ! lipid metabolic process +relationship: regulates GO:0006629 ! lipid metabolic process + +[Term] +id: GO:0019217 +name: regulation of fatty acid metabolic process +namespace: biological_process +alt_id: GO:0006632 +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] +synonym: "regulation of fatty acid metabolism" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006631 ! fatty acid metabolic process +relationship: regulates GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0019218 +name: regulation of steroid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] +synonym: "regulation of steroid metabolism" EXACT [] +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008202 ! steroid metabolic process +relationship: regulates GO:0008202 ! steroid metabolic process + +[Term] +id: GO:0019219 +name: regulation of nucleobase-containing compound metabolic process +namespace: biological_process +def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] +synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006139 ! nucleobase-containing compound metabolic process +relationship: regulates GO:0006139 ! nucleobase-containing compound metabolic process + +[Term] +id: GO:0019220 +name: regulation of phosphate metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] +synonym: "regulation of phosphate metabolism" EXACT [] +is_a: GO:0051174 ! regulation of phosphorus metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process +relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process + +[Term] +id: GO:0019221 +name: cytokine-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:19295629] +synonym: "cytokine and chemokine mediated signaling pathway" EXACT [] +synonym: "cytokine mediated signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway +relationship: part_of GO:0071345 ! cellular response to cytokine stimulus + +[Term] +id: GO:0019222 +name: regulation of metabolic process +namespace: biological_process +alt_id: GO:0044246 +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] +subset: goslim_metagenomics +synonym: "regulation of metabolism" EXACT [] +synonym: "regulation of multicellular organismal metabolic process" NARROW [] +synonym: "regulation of organismal metabolic process" NARROW [GOC:tb] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008152 ! metabolic process +relationship: regulates GO:0008152 ! metabolic process + +[Term] +id: GO:0019226 +name: transmission of nerve impulse +namespace: biological_process +def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194] +synonym: "conduction of nerve impulse" EXACT [GOC:dph] +synonym: "signal transmission along a neuron" EXACT [] +is_a: GO:0035637 ! multicellular organismal signaling +is_a: GO:0050877 ! nervous system process +relationship: has_part GO:0001508 ! action potential +relationship: has_part GO:0007268 ! chemical synaptic transmission +relationship: part_of GO:0007154 ! cell communication + +[Term] +id: GO:0019227 +name: neuronal action potential propagation +namespace: biological_process +def: "The propagation of an action potential along an axon, away from the soma." [GOC:isa_complete] +is_a: GO:0050877 ! nervous system process +is_a: GO:0098870 ! action potential propagation +relationship: part_of GO:0019226 ! transmission of nerve impulse + +[Term] +id: GO:0019228 +name: neuronal action potential +namespace: biological_process +def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb] +synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001508 ! action potential +relationship: part_of GO:0019226 ! transmission of nerve impulse + +[Term] +id: GO:0019229 +name: regulation of vasoconstriction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels." [GOC:jl] +is_a: GO:0097746 ! regulation of blood vessel diameter +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042310 ! vasoconstriction +relationship: regulates GO:0042310 ! vasoconstriction + +[Term] +id: GO:0019230 +name: proprioception +namespace: biological_process +def: "The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors." [ISBN:072168677X] +xref: Wikipedia:Proprioception +is_a: GO:0007600 ! sensory perception +relationship: part_of GO:0050884 ! neuromuscular process controlling posture + +[Term] +id: GO:0019231 +name: perception of static position +namespace: biological_process +def: "The perception of the orientation of different parts of the body with respect to one another." [ISBN:072168677X] +is_a: GO:0019230 ! proprioception + +[Term] +id: GO:0019232 +name: perception of rate of movement +namespace: biological_process +def: "The series of events by which an organism senses the speed and direction of movement of the body and its parts." [GOC:mah] +synonym: "kinesthesia" EXACT [] +is_a: GO:0019230 ! proprioception + +[Term] +id: GO:0019233 +name: sensory perception of pain +namespace: biological_process +def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." [GOC:curators] +synonym: "nociception" EXACT [] +synonym: "perception of physiological pain" NARROW [] +xref: Wikipedia:Nociception +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0019234 +name: sensory perception of fast pain +namespace: biological_process +def: "The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds." [http://www.spine-health.com/] +is_a: GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0019235 +name: sensory perception of slow pain +namespace: biological_process +def: "The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction." [http://www.people.vcu.edu/~mikuleck/ssspain/, http://www.spine-health.com/] +is_a: GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0019236 +name: response to pheromone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus." [GOC:jl] +synonym: "pheromone response" EXACT [] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0019237 +name: centromeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis." [GOC:jl, SO:0000577] +synonym: "centromere binding" EXACT [] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0019238 +name: cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring." [GOC:mah] +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0019239 +name: deaminase activity +namespace: molecular_function +def: "Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3)." [GOC:jl] +subset: goslim_pir +xref: Reactome:R-HSA-9014641 "HRSP12 deaminates 2AA to 2OBUTA" +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0019240 +name: citrulline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins." [ISBN:0198506732] +synonym: "citrulline anabolism" EXACT [] +synonym: "citrulline biosynthesis" EXACT [] +synonym: "citrulline formation" EXACT [] +synonym: "citrulline synthesis" EXACT [] +xref: MetaCyc:CITRULBIO-PWY +is_a: GO:0000052 ! citrulline metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0019241 +name: citrulline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins." [ISBN:0198506732] +synonym: "citrulline breakdown" EXACT [] +synonym: "citrulline catabolism" EXACT [] +synonym: "citrulline degradation" EXACT [] +xref: MetaCyc:CITRULLINE-DEG-PWY +is_a: GO:0000052 ! citrulline metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019242 +name: methylglyoxal biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid." [GOC:ai] +synonym: "methylglyoxal anabolism" EXACT [] +synonym: "methylglyoxal biosynthesis" EXACT [] +synonym: "methylglyoxal formation" EXACT [] +synonym: "methylglyoxal synthesis" EXACT [] +is_a: GO:0009438 ! methylglyoxal metabolic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process + +[Term] +id: GO:0019243 +name: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step." [GOC:ai, GOC:dph, PMID:2198020] +synonym: "D-lactate biosynthesis from methylglyoxal" BROAD [] +synonym: "D-lactate biosynthetic process from methylglyoxal" BROAD [] +synonym: "glyoxalase system" RELATED [] +synonym: "methylglyoxal breakdown to D-lactate" BROAD [] +synonym: "methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione" EXACT [] +synonym: "methylglyoxal degradation to D-lactate" BROAD [] +synonym: "methylglyoxal detoxification" RELATED [] +xref: MetaCyc:PWY-5386 +is_a: GO:0061727 ! methylglyoxal catabolic process to lactate + +[Term] +id: GO:0019244 +name: lactate biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate." [GOC:go_curators] +synonym: "lactate anabolism from pyruvate" EXACT [] +synonym: "lactate formation from pyruvate" EXACT [] +synonym: "lactate synthesis from pyruvate" EXACT [] +synonym: "pyruvate fermentation to lactate" EXACT [] +xref: Reactome:R-HSA-71849.1 +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0019249 ! lactate biosynthetic process +relationship: has_part GO:0004457 ! lactate dehydrogenase activity + +[Term] +id: GO:0019245 +name: D(-)-lactate biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate." [GOC:go_curators] +synonym: "D(-)-lactate anabolism from pyruvate" EXACT [] +synonym: "D(-)-lactate formation from pyruvate" EXACT [] +synonym: "D(-)-lactate synthesis from pyruvate" EXACT [] +is_a: GO:0019244 ! lactate biosynthetic process from pyruvate +relationship: has_part GO:0008720 ! D-lactate dehydrogenase activity + +[Term] +id: GO:0019246 +name: L(+)-lactate biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate." [GOC:go_curators] +synonym: "L(+)-lactate anabolism from pyruvate" EXACT [] +synonym: "L(+)-lactate formation from pyruvate" EXACT [] +synonym: "L(+)-lactate synthesis from pyruvate" EXACT [] +synonym: "S-lactate biosynthetic process from pyruvate" EXACT [] +xref: MetaCyc:PWY-5481 +is_a: GO:0019244 ! lactate biosynthetic process from pyruvate +relationship: has_part GO:0004459 ! L-lactate dehydrogenase activity + +[Term] +id: GO:0019247 +name: lactate racemization +namespace: biological_process +def: "Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture." [GOC:curators, PMID:16166538] +is_a: GO:0006089 ! lactate metabolic process + +[Term] +id: GO:0019248 +name: D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde." [GOC:dph, GOC:go_curators, MetaCyc:MGLDLCTANA-PWY] +synonym: "D-lactate anabolism from methylglyoxal via (R)-lactaldehyde" EXACT [] +synonym: "D-lactate formation from methylglyoxal via (R)-lactaldehyde" EXACT [] +synonym: "D-lactate synthesis from methylglyoxal via (R)-lactaldehyde" EXACT [] +xref: MetaCyc:MGLDLCTANA-PWY +is_a: GO:0019249 ! lactate biosynthetic process +is_a: GO:0061727 ! methylglyoxal catabolic process to lactate + +[Term] +id: GO:0019249 +name: lactate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid." [GOC:go_curators] +synonym: "lactate anabolism" EXACT [] +synonym: "lactate biosynthesis" EXACT [] +synonym: "lactate formation" EXACT [] +synonym: "lactate synthesis" EXACT [] +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0019250 +name: aerobic cobalamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen." [GOC:go_curators] +synonym: "aerobic cobalamin anabolism" EXACT [] +synonym: "aerobic cobalamin biosynthesis" EXACT [] +synonym: "aerobic cobalamin formation" EXACT [] +synonym: "aerobic cobalamin synthesis" EXACT [] +synonym: "aerobic vitamin B12 biosynthesis" EXACT [] +synonym: "aerobic vitamin B12 biosynthetic process" EXACT [] +synonym: "cobalamin biosynthesis, aerobic" EXACT [] +synonym: "cobalamin biosynthetic process, aerobic" EXACT [] +synonym: "vitamin B12 biosynthesis, aerobic" EXACT [] +synonym: "vitamin B12 biosynthetic process, aerobic" EXACT [] +xref: MetaCyc:P381-PWY +is_a: GO:0009236 ! cobalamin biosynthetic process + +[Term] +id: GO:0019251 +name: anaerobic cobalamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen." [GOC:go_curators] +synonym: "anaerobic cobalamin anabolism" EXACT [] +synonym: "anaerobic cobalamin biosynthesis" EXACT [] +synonym: "anaerobic cobalamin formation" EXACT [] +synonym: "anaerobic cobalamin synthesis" EXACT [] +synonym: "anaerobic vitamin B12 biosynthesis" EXACT [] +synonym: "anaerobic vitamin B12 biosynthetic process" EXACT [] +synonym: "cobalamin biosynthesis, anaerobic" EXACT [] +synonym: "cobalamin biosynthetic process, anaerobic" EXACT [] +synonym: "vitamin B12 biosynthesis, anaerobic" EXACT [] +synonym: "vitamin B12 biosynthetic process, anaerobic" EXACT [] +xref: MetaCyc:COBALSYN-PWY +is_a: GO:0009236 ! cobalamin biosynthetic process + +[Term] +id: GO:0019252 +name: starch biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants." [GOC:ai] +synonym: "starch anabolism" EXACT [] +synonym: "starch biosynthesis" EXACT [] +synonym: "starch formation" EXACT [] +synonym: "starch synthesis" EXACT [] +xref: MetaCyc:PWY-622 +is_a: GO:0005982 ! starch metabolic process +is_a: GO:0009250 ! glucan biosynthetic process + +[Term] +id: GO:0019253 +name: reductive pentose-phosphate cycle +namespace: biological_process +def: "The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate." [ISBN:0198547684] +comment: See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'. +synonym: "C3 photosynthesis" NARROW [] +synonym: "Calvin cycle" NARROW [] +xref: MetaCyc:CALVIN-PWY +is_a: GO:0019685 ! photosynthesis, dark reaction +relationship: part_of GO:0015977 ! carbon fixation + +[Term] +id: GO:0019254 +name: carnitine metabolic process, CoA-linked +namespace: biological_process +def: "The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA." [GOC:go_curators] +synonym: "carnitine metabolism, CoA-linked" EXACT [] +xref: MetaCyc:CARNMET-PWY +is_a: GO:0009437 ! carnitine metabolic process + +[Term] +id: GO:0019255 +name: glucose 1-phosphate metabolic process +namespace: biological_process +alt_id: GO:0006008 +def: "The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1." [GOC:ai] +synonym: "glucose 1-phosphate metabolism" EXACT [] +synonym: "glucose 1-phosphate utilization" RELATED [GOC:mah] +xref: MetaCyc:GLUCOSE1PMETAB-PWY +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0019256 +name: acrylonitrile catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers." [GOC:ai] +synonym: "acrylonitrile breakdown" EXACT [] +synonym: "acrylonitrile catabolism" EXACT [] +synonym: "acrylonitrile degradation" EXACT [] +xref: MetaCyc:P344-PWY +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018865 ! acrylonitrile metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0050899 ! nitrile catabolic process + +[Term] +id: GO:0019257 +name: 4-nitrotoluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor." [GOC:ai] +synonym: "4-nitrotoluene metabolism" EXACT [] +synonym: "4NT metabolic process" EXACT [] +synonym: "4NT metabolism" EXACT [] +is_a: GO:0019326 ! nitrotoluene metabolic process + +[Term] +id: GO:0019258 +name: 4-nitrotoluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene." [GOC:ai] +synonym: "4-nitrotoluene breakdown" EXACT [] +synonym: "4-nitrotoluene catabolism" EXACT [] +synonym: "4-nitrotoluene degradation" EXACT [] +synonym: "4NT catabolic process" EXACT [] +synonym: "4NT catabolism" EXACT [] +xref: MetaCyc:P421-PWY +is_a: GO:0019257 ! 4-nitrotoluene metabolic process +is_a: GO:0046263 ! nitrotoluene catabolic process + +[Term] +id: GO:0019260 +name: 1,2-dichloroethane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride." [GOC:go_curators] +synonym: "1,2-dichloroethane breakdown" EXACT [] +synonym: "1,2-dichloroethane catabolism" EXACT [] +synonym: "1,2-dichloroethane degradation" EXACT [] +xref: MetaCyc:12DICHLORETHDEG-PWY +is_a: GO:0018899 ! 1,2-dichloroethane metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0019261 +name: 1,4-dichlorobenzene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring." [GOC:ai] +synonym: "1,4-dichlorobenzene breakdown" EXACT [] +synonym: "1,4-dichlorobenzene catabolism" EXACT [] +synonym: "1,4-dichlorobenzene degradation" EXACT [] +xref: MetaCyc:14DICHLORBENZDEG-PWY +is_a: GO:0018912 ! 1,4-dichlorobenzene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046701 ! insecticide catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019262 +name: N-acetylneuraminate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid." [ISBN:0198506732] +synonym: "N-acetylneuraminate breakdown" EXACT [] +synonym: "N-acetylneuraminate catabolism" EXACT [] +synonym: "N-acetylneuraminate degradation" EXACT [] +xref: MetaCyc:P441-PWY +is_a: GO:0006054 ! N-acetylneuraminate metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046348 ! amino sugar catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0019263 +name: adamantanone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists." [GOC:ai] +synonym: "adamantanone breakdown" EXACT [] +synonym: "adamantanone catabolism" EXACT [] +synonym: "adamantanone degradation" EXACT [] +xref: MetaCyc:P481-PWY +is_a: GO:0018866 ! adamantanone metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019264 +name: glycine biosynthetic process from serine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine." [GOC:go_curators] +synonym: "glycine anabolism from serine" EXACT [] +synonym: "glycine formation from serine" EXACT [] +synonym: "glycine synthesis from serine" EXACT [] +xref: MetaCyc:GLYSYN-PWY +is_a: GO:0006545 ! glycine biosynthetic process +is_a: GO:0006563 ! L-serine metabolic process + +[Term] +id: GO:0019265 +name: glycine biosynthetic process, by transamination of glyoxylate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate." [GOC:go_curators] +synonym: "glycine anabolism, by transamination of glyoxylate" EXACT [] +synonym: "glycine formation, by transamination of glyoxylate" EXACT [] +synonym: "glycine synthesis, by transamination of glyoxylate" EXACT [] +is_a: GO:0006545 ! glycine biosynthetic process + +[Term] +id: GO:0019266 +name: asparagine biosynthetic process from oxaloacetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate." [GOC:go_curators] +synonym: "asparagine anabolism from oxaloacetate" EXACT [] +synonym: "asparagine formation from oxaloacetate" EXACT [] +synonym: "asparagine synthesis from oxaloacetate" EXACT [] +xref: MetaCyc:ASPARAGINE-BIOSYNTHESIS +is_a: GO:0006107 ! oxaloacetate metabolic process +is_a: GO:0006529 ! asparagine biosynthetic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0019267 +name: asparagine biosynthetic process from cysteine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine." [GOC:go_curators] +synonym: "asparagine anabolism from cysteine" EXACT [] +synonym: "asparagine formation from cysteine" EXACT [] +synonym: "asparagine synthesis from cysteine" EXACT [] +xref: MetaCyc:ASPSYNII-PWY +is_a: GO:0006529 ! asparagine biosynthetic process +is_a: GO:0006534 ! cysteine metabolic process + +[Term] +id: GO:0019268 +name: obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+)." [GOC:go_curators] +comment: This term was made obsolete because it represents a molecular function. +synonym: "glutamate anabolism, using glutamate dehydrogenase (NAD(P)+)" EXACT [] +synonym: "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)" EXACT [] +synonym: "glutamate formation, using glutamate dehydrogenase (NAD(P)+)" EXACT [] +synonym: "glutamate synthesis, using glutamate dehydrogenase (NAD(P)+)" EXACT [] +is_obsolete: true +consider: GO:0004353 +consider: GO:0006537 + +[Term] +id: GO:0019269 +name: obsolete glutamate biosynthetic process, using glutamate synthase (NADPH) +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH)." [GOC:go_curators] +comment: This term was made obsolete because it refers to a molecular function. +synonym: "glutamate anabolism, using glutamate synthase (NADPH)" EXACT [] +synonym: "glutamate biosynthetic process, using glutamate synthase (NADPH)" EXACT [] +synonym: "glutamate formation, using glutamate synthase (NADPH)" EXACT [] +synonym: "glutamate synthesis, using glutamate synthase (NADPH)" EXACT [] +is_obsolete: true +consider: GO:0004355 +consider: GO:0006537 + +[Term] +id: GO:0019270 +name: aerobactin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid." [GOC:ai] +synonym: "aerobactin anabolism" EXACT [] +synonym: "aerobactin biosynthesis" EXACT [] +synonym: "aerobactin formation" EXACT [] +synonym: "aerobactin synthesis" EXACT [] +xref: MetaCyc:AEROBACTINSYN-PWY +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0046442 ! aerobactin metabolic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process + +[Term] +id: GO:0019271 +name: aerobactin transport +namespace: biological_process +def: "The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid." [GOC:ai, PMID:23192658] +is_a: GO:0006842 ! tricarboxylic acid transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0019272 +name: L-alanine biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate." [GOC:go_curators] +synonym: "L-alanine anabolism from pyruvate" EXACT [] +synonym: "L-alanine formation from pyruvate" EXACT [] +synonym: "L-alanine synthesis from pyruvate" EXACT [] +xref: MetaCyc:ALANINE-SYN2-PWY +xref: MetaCyc:ALANINE-VALINESYN-PWY +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0042852 ! L-alanine biosynthetic process + +[Term] +id: GO:0019273 +name: L-alanine biosynthetic process via ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine." [GOC:go_curators] +synonym: "L-alanine anabolism via ornithine" EXACT [] +synonym: "L-alanine formation via ornithine" EXACT [] +synonym: "L-alanine synthesis via ornithine" EXACT [] +is_a: GO:0006591 ! ornithine metabolic process +is_a: GO:0042852 ! L-alanine biosynthetic process + +[Term] +id: GO:0019276 +name: UDP-N-acetylgalactosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylgalactosamine metabolism" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0019277 +name: UDP-N-acetylgalactosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylgalactosamine anabolism" EXACT [] +synonym: "UDP-N-acetylgalactosamine biosynthesis" EXACT [] +synonym: "UDP-N-acetylgalactosamine formation" EXACT [] +synonym: "UDP-N-acetylgalactosamine synthesis" EXACT [] +xref: MetaCyc:UDPNACETYLGALSYN-PWY +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0019276 ! UDP-N-acetylgalactosamine metabolic process +is_a: GO:0046349 ! amino sugar biosynthetic process + +[Term] +id: GO:0019278 +name: UDP-N-acetylgalactosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-N-acetylgalactosamine breakdown" EXACT [] +synonym: "UDP-N-acetylgalactosamine catabolism" EXACT [] +synonym: "UDP-N-acetylgalactosamine degradation" EXACT [] +is_a: GO:0009227 ! nucleotide-sugar catabolic process +is_a: GO:0019276 ! UDP-N-acetylgalactosamine metabolic process +is_a: GO:0046348 ! amino sugar catabolic process + +[Term] +id: GO:0019279 +name: L-methionine biosynthetic process from L-homoserine via cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine." [GOC:go_curators] +synonym: "L-methionine anabolism from L-homoserine via cystathionine" EXACT [GOC:mah] +synonym: "L-methionine formation from L-homoserine via cystathionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from L-homoserine via cystathionine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process from L-homoserine via cystathionine" EXACT [GOC:mah] +xref: MetaCyc:HOMOSER-METSYN-PWY +is_a: GO:0009092 ! homoserine metabolic process +is_a: GO:0071266 ! 'de novo' L-methionine biosynthetic process + +[Term] +id: GO:0019280 +name: L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine." [GOC:go_curators] +synonym: "L-methionine anabolism from homoserine via O-acetyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine formation from homoserine via O-acetyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from homoserine via O-acetyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine" EXACT [GOC:mah] +xref: MetaCyc:HSERMETANA-PWY +is_a: GO:0019279 ! L-methionine biosynthetic process from L-homoserine via cystathionine + +[Term] +id: GO:0019281 +name: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine." [GOC:go_curators] +synonym: "L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine" EXACT [GOC:mah] +xref: MetaCyc:MET-SAM-PWY +is_a: GO:0019279 ! L-methionine biosynthetic process from L-homoserine via cystathionine + +[Term] +id: GO:0019283 +name: L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine." [GOC:go_curators] +synonym: "L-methionine anabolism from O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine formation from O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process from O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0071266 ! 'de novo' L-methionine biosynthetic process + +[Term] +id: GO:0019284 +name: L-methionine salvage from S-adenosylmethionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine." [GOC:go_curators, GOC:vw] +synonym: "L-methionine formation from S-adenosylmethionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from S-adenosylmethionine" EXACT [GOC:mah] +is_a: GO:0071267 ! L-methionine salvage +relationship: part_of GO:0033353 ! S-adenosylmethionine cycle + +[Term] +id: GO:0019285 +name: glycine betaine biosynthetic process from choline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline." [GOC:jl] +synonym: "choline oxidation" EXACT [GOC:dph, PMID:23563483] +synonym: "glycine betaine anabolism from choline" EXACT [] +synonym: "glycine betaine formation from choline" EXACT [] +synonym: "glycine betaine synthesis from choline" EXACT [] +synonym: "N-trimethylglycine biosynthesis from choline" EXACT [] +synonym: "N-trimethylglycine biosynthetic process from choline" EXACT [] +xref: MetaCyc:BETSYN-PWY +xref: MetaCyc:CHOLINE-BETAINE-ANA-PWY +xref: MetaCyc:P542-PWY +is_a: GO:0019695 ! choline metabolic process +is_a: GO:0031456 ! glycine betaine biosynthetic process + +[Term] +id: GO:0019286 +name: glycine betaine biosynthetic process from glycine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine." [GOC:go_curators] +synonym: "glycine betaine anabolism from glycine" EXACT [] +synonym: "glycine betaine formation from glycine" EXACT [] +synonym: "glycine betaine synthesis from glycine" EXACT [] +synonym: "N-trimethylglycine biosynthesis from glycine" EXACT [] +synonym: "N-trimethylglycine biosynthetic process from glycine" EXACT [] +xref: MetaCyc:P541-PWY +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0031456 ! glycine betaine biosynthetic process + +[Term] +id: GO:0019287 +name: isopentenyl diphosphate biosynthetic process, mevalonate pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates." [GOC:go_curators, MetaCyc:PWY-922] +synonym: "Ac-MVA pathway" EXACT [PMID:14517367] +synonym: "acetate-mevalonate pathway" EXACT [PMID:14517367] +synonym: "isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [] +synonym: "isopentenyl diphosphate biosynthetic process via mevalonate" EXACT [GOC:pr] +synonym: "isopentenyl diphosphate formation, mevalonate pathway" EXACT [] +synonym: "isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [] +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0009240 ! isopentenyl diphosphate biosynthetic process + +[Term] +id: GO:0019288 +name: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate." [GOC:go_curators, MetaCyc:NONMEVIPP-PWY, PMID:18948055] +synonym: "isopentenyl diphosphate anabolism, mevalonate-independent pathway" EXACT [] +synonym: "isopentenyl diphosphate biosynthesis, mevalonate-independent" EXACT [] +synonym: "isopentenyl diphosphate biosynthesis, non-mevalonate pathway" EXACT [] +synonym: "isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate" EXACT [GOC:pr] +synonym: "isopentenyl diphosphate biosynthetic process, MEP pathway" EXACT [] +synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent" EXACT [] +synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] +synonym: "isopentenyl diphosphate biosynthetic process, non-mevalonate pathway" EXACT [] +synonym: "isopentenyl diphosphate formation, mevalonate-independent pathway" EXACT [] +synonym: "isopentenyl diphosphate synthesis, mevalonate-independent pathway" EXACT [] +synonym: "mevalonate-independent isopentenyl diphosphate biosynthesis" EXACT [] +synonym: "mevalonate-independent isopentenyl diphosphate biosynthetic process" EXACT [] +synonym: "non-MVA pathway" EXACT [] +xref: MetaCyc:NONMEVIPP-PWY +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0009240 ! isopentenyl diphosphate biosynthetic process +is_a: GO:0019682 ! glyceraldehyde-3-phosphate metabolic process + +[Term] +id: GO:0019289 +name: rhizobactin 1021 biosynthetic process +namespace: biological_process +alt_id: GO:0031193 +alt_id: GO:0031194 +def: "The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti." [MetaCyc:PWY-761, PMID:11274118] +synonym: "rhizobactin 1021 anabolism" EXACT [] +synonym: "rhizobactin 1021 biosynthesis" EXACT [] +synonym: "rhizobactin 1021 biosynthetic process, peptide formation" NARROW [] +synonym: "rhizobactin 1021 biosynthetic process, peptide modification" NARROW [] +synonym: "rhizobactin 1021 formation" EXACT [] +synonym: "rhizobactin 1021 synthesis" EXACT [] +xref: MetaCyc:PWY-761 +is_a: GO:0019540 ! siderophore biosynthetic process from catechol +is_a: GO:0046494 ! rhizobactin 1021 metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process + +[Term] +id: GO:0019290 +name: siderophore biosynthetic process +namespace: biological_process +alt_id: GO:0031178 +alt_id: GO:0031180 +def: "The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action." [GOC:go_curators] +comment: See also the biological process term 'nonribosomal peptide biosynthetic process ; GO:0019184'. +synonym: "siderochrome biosynthesis" NARROW [] +synonym: "siderochrome biosynthetic process" NARROW [] +synonym: "siderophore anabolism" EXACT [] +synonym: "siderophore biosynthesis" EXACT [] +synonym: "siderophore biosynthetic process, peptide formation" NARROW [] +synonym: "siderophore biosynthetic process, peptide modification" NARROW [] +synonym: "siderophore formation" EXACT [] +synonym: "siderophore synthesis" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0019184 ! nonribosomal peptide biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0019292 +name: tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate." [GOC:go_curators] +synonym: "tyrosine anabolism from chorismate via 4-hydroxyphenylpyruvate" EXACT [] +synonym: "tyrosine biosynthetic process from chorismate via p-hydroxyphenylpyruvate" EXACT [] +synonym: "tyrosine formation from chorismate via 4-hydroxyphenylpyruvate" EXACT [] +synonym: "tyrosine synthesis from chorismate via 4-hydroxyphenylpyruvate" EXACT [] +xref: MetaCyc:TYRSYN +is_a: GO:0006571 ! tyrosine biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0019293 +name: tyrosine biosynthetic process, by oxidation of phenylalanine +namespace: biological_process +alt_id: GO:0019291 +def: "The chemical reactions and pathways resulting in the formation of tyrosine by the oxidation of phenylalanine." [GOC:go_curators] +synonym: "tyrosine anabolism from chorismate via L-phenylalanine" EXACT [] +synonym: "tyrosine anabolism, by oxidation of phenylalanine" EXACT [] +synonym: "tyrosine biosynthetic process from chorismate via L-phenylalanine" EXACT [] +synonym: "tyrosine formation from chorismate via L-phenylalanine" EXACT [] +synonym: "tyrosine formation, by oxidation of phenylalanine" EXACT [] +synonym: "tyrosine synthesis from chorismate via L-phenylalanine" EXACT [] +synonym: "tyrosine synthesis, by oxidation of phenylalanine" EXACT [] +is_a: GO:0006558 ! L-phenylalanine metabolic process +is_a: GO:0006571 ! tyrosine biosynthetic process +is_a: GO:0055114 ! oxidation-reduction process +relationship: has_part GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019294 +name: keto-3-deoxy-D-manno-octulosonic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria." [ISBN:0198506732] +synonym: "KDO biosynthesis" EXACT [] +synonym: "KDO biosynthetic process" EXACT [] +synonym: "keto-3-deoxy-D-manno-octulosonic acid anabolism" EXACT [] +synonym: "keto-3-deoxy-D-manno-octulosonic acid biosynthesis" EXACT [] +synonym: "keto-3-deoxy-D-manno-octulosonic acid formation" EXACT [] +synonym: "keto-3-deoxy-D-manno-octulosonic acid synthesis" EXACT [] +synonym: "ketodeoxyoctanoate biosynthetic process" RELATED [ISBN:0198506732] +xref: MetaCyc:KDOSYN-PWY +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0046400 ! keto-3-deoxy-D-manno-octulosonic acid metabolic process +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0019295 +name: coenzyme M biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes." [ISBN:0198547684] +synonym: "coenzyme M anabolism" EXACT [] +synonym: "coenzyme M biosynthesis" EXACT [] +synonym: "coenzyme M formation" EXACT [] +synonym: "coenzyme M synthesis" EXACT [] +xref: MetaCyc:P261-PWY +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0016053 ! organic acid biosynthetic process +is_a: GO:0019296 ! coenzyme M metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0019296 +name: coenzyme M metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes." [GOC:go_curators] +synonym: "coenzyme M metabolism" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0019297 +name: coenzyme B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes." [GOC:go_curators] +synonym: "coenzyme B metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0019298 +name: coenzyme B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes." [PMID:10940051] +synonym: "coenzyme B anabolism" EXACT [] +synonym: "coenzyme B biosynthesis" EXACT [] +synonym: "coenzyme B formation" EXACT [] +synonym: "coenzyme B synthesis" EXACT [] +xref: MetaCyc:P241-PWY +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0019297 ! coenzyme B metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0019299 +name: rhamnose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [ISBN:0198506732] +synonym: "rhamnose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0019300 +name: rhamnose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose." [ISBN:0198506732] +synonym: "rhamnose anabolism" EXACT [] +synonym: "rhamnose biosynthesis" EXACT [] +synonym: "rhamnose formation" EXACT [] +synonym: "rhamnose synthesis" EXACT [] +is_a: GO:0019299 ! rhamnose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0019301 +name: rhamnose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose." [ISBN:0198506732] +synonym: "rhamnose breakdown" EXACT [] +synonym: "rhamnose catabolism" EXACT [] +synonym: "rhamnose degradation" EXACT [] +xref: MetaCyc:RHAMCAT-PWY +is_a: GO:0019299 ! rhamnose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0019302 +name: D-ribose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose)." [ISBN:0198506732] +synonym: "D-ribose anabolism" EXACT [] +synonym: "D-ribose biosynthesis" EXACT [] +synonym: "D-ribose formation" EXACT [] +synonym: "D-ribose synthesis" EXACT [] +is_a: GO:0006014 ! D-ribose metabolic process +is_a: GO:0019322 ! pentose biosynthetic process + +[Term] +id: GO:0019303 +name: D-ribose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose)." [ISBN:0198506732] +synonym: "D-ribose breakdown" EXACT [] +synonym: "D-ribose catabolism" EXACT [] +synonym: "D-ribose degradation" EXACT [] +xref: MetaCyc:RIBOKIN-PWY +is_a: GO:0006014 ! D-ribose metabolic process +is_a: GO:0019323 ! pentose catabolic process + +[Term] +id: GO:0019304 +name: anaerobic rhamnose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen." [GOC:ai] +synonym: "anaerobic rhamnose breakdown" EXACT [] +synonym: "anaerobic rhamnose catabolism" EXACT [] +synonym: "anaerobic rhamnose degradation" EXACT [] +is_a: GO:0019301 ! rhamnose catabolic process + +[Term] +id: GO:0019305 +name: dTDP-rhamnose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate." [GOC:ai] +synonym: "dTDP-rhamnose anabolism" EXACT [] +synonym: "dTDP-rhamnose biosynthesis" EXACT [] +synonym: "dTDP-rhamnose formation" EXACT [] +synonym: "dTDP-rhamnose synthesis" EXACT [] +xref: MetaCyc:DTDPRHAMSYN-PWY +xref: MetaCyc:PWY-3221 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046383 ! dTDP-rhamnose metabolic process + +[Term] +id: GO:0019306 +name: GDP-D-rhamnose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-D-rhamnose anabolism" EXACT [] +synonym: "GDP-D-rhamnose biosynthesis" EXACT [] +synonym: "GDP-D-rhamnose formation" EXACT [] +synonym: "GDP-D-rhamnose synthesis" EXACT [] +xref: MetaCyc:GDPRHAMSYN-PWY +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046382 ! GDP-D-rhamnose metabolic process + +[Term] +id: GO:0019307 +name: mannose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose." [GOC:ai] +synonym: "mannose anabolism" EXACT [] +synonym: "mannose biosynthesis" EXACT [] +synonym: "mannose formation" EXACT [] +synonym: "mannose synthesis" EXACT [] +is_a: GO:0006013 ! mannose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0019308 +name: dTDP-mannose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate." [GOC:ai] +synonym: "dTDP-mannose anabolism" EXACT [] +synonym: "dTDP-mannose biosynthesis" EXACT [] +synonym: "dTDP-mannose formation" EXACT [] +synonym: "dTDP-mannose synthesis" EXACT [] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046371 ! dTDP-mannose metabolic process + +[Term] +id: GO:0019309 +name: mannose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose." [GOC:ai] +synonym: "mannose breakdown" EXACT [] +synonym: "mannose catabolism" EXACT [] +synonym: "mannose degradation" EXACT [] +xref: MetaCyc:MANNCAT-PWY +is_a: GO:0006013 ! mannose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0019310 +name: inositol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms." [GOC:go_curators] +synonym: "inositol breakdown" EXACT [] +synonym: "inositol catabolism" EXACT [] +synonym: "inositol degradation" EXACT [] +synonym: "myo-inositol catabolic process" NARROW [] +synonym: "myo-inositol catabolism" NARROW [] +synonym: "vitamin Bh catabolic process" EXACT [] +synonym: "vitamin Bh catabolism" EXACT [] +xref: MetaCyc:P562-PWY +is_a: GO:0006020 ! inositol metabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process +is_a: GO:0046174 ! polyol catabolic process + +[Term] +id: GO:0019311 +name: sorbose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid." [ISBN:0198506732] +synonym: "sorbose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0019312 +name: L-sorbose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-sorbose metabolism" EXACT [] +xref: MetaCyc:P302-PWY +is_a: GO:0019311 ! sorbose metabolic process + +[Term] +id: GO:0019313 +name: allose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [ISBN:0198506732] +synonym: "allose metabolism" EXACT [] +is_a: GO:0019318 ! hexose metabolic process + +[Term] +id: GO:0019314 +name: D-allose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-allose metabolism" EXACT [] +is_a: GO:0019313 ! allose metabolic process + +[Term] +id: GO:0019315 +name: D-allose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-allose anabolism" EXACT [] +synonym: "D-allose biosynthesis" EXACT [] +synonym: "D-allose formation" EXACT [] +synonym: "D-allose synthesis" EXACT [] +is_a: GO:0019314 ! D-allose metabolic process +is_a: GO:0046366 ! allose biosynthetic process + +[Term] +id: GO:0019316 +name: D-allose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-allose breakdown" EXACT [] +synonym: "D-allose catabolism" EXACT [] +synonym: "D-allose degradation" EXACT [] +xref: MetaCyc:PWY0-44 +is_a: GO:0019314 ! D-allose metabolic process +is_a: GO:0046367 ! allose catabolic process + +[Term] +id: GO:0019317 +name: fucose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose)." [GOC:jl] +synonym: "fucose breakdown" EXACT [] +synonym: "fucose catabolism" EXACT [] +synonym: "fucose degradation" EXACT [] +xref: MetaCyc:FUCCAT-PWY +is_a: GO:0006004 ! fucose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0019318 +name: hexose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexose metabolism" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process + +[Term] +id: GO:0019319 +name: hexose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexose anabolism" EXACT [] +synonym: "hexose biosynthesis" EXACT [] +synonym: "hexose formation" EXACT [] +synonym: "hexose synthesis" EXACT [] +is_a: GO:0019318 ! hexose metabolic process +is_a: GO:0046364 ! monosaccharide biosynthetic process + +[Term] +id: GO:0019320 +name: hexose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexose breakdown" EXACT [] +synonym: "hexose catabolism" EXACT [] +synonym: "hexose degradation" EXACT [] +is_a: GO:0019318 ! hexose metabolic process +is_a: GO:0046365 ! monosaccharide catabolic process + +[Term] +id: GO:0019321 +name: pentose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentose metabolism" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process + +[Term] +id: GO:0019322 +name: pentose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentose anabolism" EXACT [] +synonym: "pentose biosynthesis" EXACT [] +synonym: "pentose formation" EXACT [] +synonym: "pentose synthesis" EXACT [] +is_a: GO:0019321 ! pentose metabolic process +is_a: GO:0046364 ! monosaccharide biosynthetic process + +[Term] +id: GO:0019323 +name: pentose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentose breakdown" EXACT [] +synonym: "pentose catabolism" EXACT [] +synonym: "pentose degradation" EXACT [] +is_a: GO:0019321 ! pentose metabolic process +is_a: GO:0046365 ! monosaccharide catabolic process + +[Term] +id: GO:0019324 +name: L-lyxose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-lyxose metabolism" EXACT [] +xref: MetaCyc:LYXMET-PWY +is_a: GO:0019321 ! pentose metabolic process + +[Term] +id: GO:0019325 +name: anaerobic fructose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen." [GOC:ai] +synonym: "anaerobic fructose breakdown" EXACT [] +synonym: "anaerobic fructose catabolism" EXACT [] +synonym: "anaerobic fructose degradation" EXACT [] +xref: MetaCyc:ANAEROFRUCAT-PWY +is_a: GO:0006001 ! fructose catabolic process +is_a: GO:0019317 ! fucose catabolic process + +[Term] +id: GO:0019326 +name: nitrotoluene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached." [GOC:ai] +synonym: "nitrotoluene metabolism" EXACT [] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0019327 +name: lead sulfide oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate." [MetaCyc:P301-PWY] +synonym: "lead sulphide oxidation" EXACT [GOC:mah] +synonym: "oxidation of galena" EXACT [] +synonym: "oxidation of lead sulfide" EXACT [] +xref: MetaCyc:P301-PWY +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0019328 +name: anaerobic gallate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen." [GOC:jl] +synonym: "anaerobic gallate breakdown" EXACT [] +synonym: "anaerobic gallate catabolism" EXACT [] +synonym: "anaerobic gallate degradation" EXACT [] +synonym: "anaerobic gallic acid catabolic process" EXACT [] +synonym: "anaerobic gallic acid catabolism" EXACT [] +synonym: "gallate fermentation" EXACT [] +xref: MetaCyc:P3-PWY +is_a: GO:0019396 ! gallate catabolic process + +[Term] +id: GO:0019329 +name: ammonia oxidation +namespace: biological_process +def: "The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons." [GOC:mah, MetaCyc:AMMOXID-PWY, MetaCyc:P303-PWY, MetaCyc:PWY-2242] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019330 +name: aldoxime metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH." [GOC:curators] +synonym: "aldoxime metabolism" EXACT [] +xref: MetaCyc:P345-PWY +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0019331 +name: anaerobic respiration, using ammonium as electron donor +namespace: biological_process +def: "The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2." [MetaCyc:P303-PWY] +synonym: "anaerobic ammonium oxidation" BROAD [] +synonym: "anammox" EXACT [] +xref: MetaCyc:P303-PWY +xref: Wikipedia:Anammox +is_a: GO:0009061 ! anaerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds +is_a: GO:0019329 ! ammonia oxidation +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0019332 +name: aerobic respiration, using nitrite as electron donor +namespace: biological_process +def: "The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species." [MetaCyc:P282-PWY] +synonym: "nitrite oxidation" BROAD [] +xref: MetaCyc:P282-PWY +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0019333 +name: denitrification pathway +namespace: biological_process +def: "The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen." [MetaCyc:DENITRIFICATION-PWY] +xref: MetaCyc:DENITRIFICATION-PWY +is_a: GO:0071941 ! nitrogen cycle metabolic process + +[Term] +id: GO:0019334 +name: p-cymene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants." [GOC:ai] +synonym: "p-cymene breakdown" EXACT [] +synonym: "p-cymene catabolism" EXACT [] +synonym: "p-cymene degradation" EXACT [] +xref: MetaCyc:PWY-741 +is_a: GO:0018953 ! p-cymene metabolic process +is_a: GO:0043694 ! monoterpene catabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0019335 +name: 3-methylquinoline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring." [GOC:ai] +synonym: "3-methylquinoline breakdown" EXACT [] +synonym: "3-methylquinoline catabolism" EXACT [] +synonym: "3-methylquinoline degradation" EXACT [] +xref: MetaCyc:PWY-721 +is_a: GO:0018930 ! 3-methylquinoline metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0019336 +name: phenol-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] +synonym: "phenol-containing compound breakdown" EXACT [] +synonym: "phenol-containing compound catabolism" EXACT [] +synonym: "phenol-containing compound degradation" EXACT [] +xref: MetaCyc:PHENOLDEG-PWY +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0019337 +name: tetrachloroethylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines." [GOC:ai] +synonym: "tetrachloroethene catabolic process" EXACT [] +synonym: "tetrachloroethene catabolism" EXACT [] +synonym: "tetrachloroethylene breakdown" EXACT [] +synonym: "tetrachloroethylene catabolism" EXACT [] +synonym: "tetrachloroethylene degradation" EXACT [] +xref: MetaCyc:PCEDEG-PWY +is_a: GO:0018967 ! tetrachloroethylene metabolic process +is_a: GO:0042205 ! chlorinated hydrocarbon catabolic process + +[Term] +id: GO:0019338 +name: pentachlorophenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms." [GOC:go_curators] +synonym: "pentachlorophenol breakdown" EXACT [] +synonym: "pentachlorophenol catabolism" EXACT [] +synonym: "pentachlorophenol degradation" EXACT [] +xref: MetaCyc:PCPDEG-PWY +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018961 ! pentachlorophenol metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process + +[Term] +id: GO:0019339 +name: parathion catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [UM-BBD_pathwayID:pthn] +synonym: "parathion breakdown" EXACT [] +synonym: "parathion catabolism" EXACT [] +synonym: "parathion degradation" EXACT [] +xref: MetaCyc:PARATHION-DEGRADATION-PWY +is_a: GO:0018952 ! parathion metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0046701 ! insecticide catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound + +[Term] +id: GO:0019340 +name: dibenzofuran catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond." [GOC:ai] +synonym: "dibenzofuran breakdown" EXACT [] +synonym: "dibenzofuran catabolism" EXACT [] +synonym: "dibenzofuran degradation" EXACT [] +xref: MetaCyc:P662-PWY +is_a: GO:0018893 ! dibenzofuran metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019341 +name: dibenzo-p-dioxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds." [GOC:ai] +synonym: "dibenzo-p-dioxin breakdown" EXACT [] +synonym: "dibenzo-p-dioxin catabolism" EXACT [] +synonym: "dibenzo-p-dioxin degradation" EXACT [] +xref: MetaCyc:P661-PWY +is_a: GO:0018894 ! dibenzo-p-dioxin metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019342 +name: trypanothione biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress." [MetaCyc:TRYPANOSYN-PWY, PMID:9677355] +synonym: "trypanothione anabolism" EXACT [] +synonym: "trypanothione biosynthesis" EXACT [] +synonym: "trypanothione formation" EXACT [] +synonym: "trypanothione synthesis" EXACT [] +xref: MetaCyc:TRYPANOSYN-PWY +is_a: GO:0046206 ! trypanothione metabolic process +is_a: GO:1901687 ! glutathione derivative biosynthetic process + +[Term] +id: GO:0019343 +name: cysteine biosynthetic process via cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine." [GOC:go_curators] +synonym: "cysteine anabolism via cystathionine" EXACT [] +synonym: "cysteine formation via cystathionine" EXACT [] +synonym: "cysteine synthesis via cystathionine" EXACT [] +is_a: GO:0019344 ! cysteine biosynthetic process + +[Term] +id: GO:0019344 +name: cysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid." [GOC:go_curators] +synonym: "cysteine anabolism" EXACT [] +synonym: "cysteine biosynthesis" EXACT [] +synonym: "cysteine formation" EXACT [] +synonym: "cysteine synthesis" EXACT [] +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0006534 ! cysteine metabolic process +is_a: GO:0009070 ! serine family amino acid biosynthetic process + +[Term] +id: GO:0019345 +name: cysteine biosynthetic process via S-sulfo-L-cysteine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine." [GOC:go_curators] +synonym: "cysteine anabolism via S-sulfo-L-cysteine" EXACT [] +synonym: "cysteine biosynthesis via S-sulpho-L-cysteine" EXACT [] +synonym: "cysteine biosynthetic process via S-sulpho-L-cysteine" EXACT [] +synonym: "cysteine formation via S-sulfo-L-cysteine" EXACT [] +synonym: "cysteine synthesis via S-sulfo-L-cysteine" EXACT [] +is_a: GO:0019344 ! cysteine biosynthetic process + +[Term] +id: GO:0019346 +name: transsulfuration +namespace: biological_process +def: "The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes." [MetaCyc:PWY-801] +synonym: "homocysteine-cysteine interconversion" NARROW [] +synonym: "transsulphuration" EXACT [] +xref: MetaCyc:PWY-801 +xref: Wikipedia:Transsulfuration_pathway +is_a: GO:0006534 ! cysteine metabolic process +is_a: GO:0009092 ! homoserine metabolic process +is_a: GO:0050667 ! homocysteine metabolic process + +[Term] +id: GO:0019347 +name: GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol anabolism" EXACT [] +synonym: "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthesis" EXACT [] +synonym: "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol formation" EXACT [] +synonym: "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol synthesis" EXACT [] +xref: MetaCyc:MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0046376 ! GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process + +[Term] +id: GO:0019348 +name: dolichol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units." [ISBN:0198506732] +synonym: "dolichol metabolism" EXACT [] +is_a: GO:0016093 ! polyprenol metabolic process + +[Term] +id: GO:0019349 +name: ribitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin." [ISBN:0198506732] +synonym: "ribitol metabolism" EXACT [] +is_a: GO:0019519 ! pentitol metabolic process + +[Term] +id: GO:0019350 +name: teichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues." [ISBN:0198506732] +synonym: "teichoic acid anabolism" EXACT [] +synonym: "teichoic acid biosynthesis" EXACT [] +synonym: "teichoic acid formation" EXACT [] +synonym: "teichoic acid synthesis" EXACT [] +xref: MetaCyc:TEICHOICACID-PWY +is_a: GO:0016053 ! organic acid biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process +is_a: GO:0046374 ! teichoic acid metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +relationship: part_of GO:0009273 ! peptidoglycan-based cell wall biogenesis + +[Term] +id: GO:0019351 +name: dethiobiotin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms." [GOC:ai, ISBN:0198506732] +synonym: "desthiobiotin biosynthesis" EXACT [] +synonym: "desthiobiotin biosynthetic process" EXACT [] +synonym: "dethiobiotin anabolism" EXACT [] +synonym: "dethiobiotin biosynthesis" EXACT [] +synonym: "dethiobiotin formation" EXACT [] +synonym: "dethiobiotin synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0046450 ! dethiobiotin metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0019352 +name: protoporphyrinogen IX biosynthetic process from glycine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine." [GOC:go_curators] +synonym: "protoporphyrinogen IX anabolism from glycine" EXACT [] +synonym: "protoporphyrinogen IX formation from glycine" EXACT [] +synonym: "protoporphyrinogen IX synthesis from glycine" EXACT [] +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0006782 ! protoporphyrinogen IX biosynthetic process + +[Term] +id: GO:0019353 +name: protoporphyrinogen IX biosynthetic process from glutamate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate." [GOC:go_curators] +synonym: "protoporphyrinogen IX anabolism from glutamate" EXACT [] +synonym: "protoporphyrinogen IX formation from glutamate" EXACT [] +synonym: "protoporphyrinogen IX synthesis from glutamate" EXACT [] +is_a: GO:0006782 ! protoporphyrinogen IX biosynthetic process +is_a: GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0019354 +name: siroheme biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings." [ISBN:0198506732] +synonym: "sirohaem biosynthesis" EXACT [] +synonym: "sirohaem biosynthetic process" EXACT [] +synonym: "siroheme anabolism" EXACT [] +synonym: "siroheme biosynthesis" EXACT [] +synonym: "siroheme formation" EXACT [] +synonym: "siroheme synthase activity" RELATED [] +synonym: "siroheme synthesis" EXACT [] +xref: MetaCyc:PWY-5194 +is_a: GO:0006783 ! heme biosynthetic process +is_a: GO:0046156 ! siroheme metabolic process + +[Term] +id: GO:0019355 +name: nicotinamide nucleotide biosynthetic process from aspartate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate." [GOC:go_curators] +synonym: "nicotinamide nucleotide anabolism from aspartate" EXACT [] +synonym: "nicotinamide nucleotide formation from aspartate" EXACT [] +synonym: "nicotinamide nucleotide synthesis from aspartate" EXACT [] +is_a: GO:0006531 ! aspartate metabolic process +is_a: GO:0019359 ! nicotinamide nucleotide biosynthetic process + +[Term] +id: GO:0019356 +name: nicotinate nucleotide biosynthetic process from tryptophan +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan." [GOC:go_curators] +synonym: "nicotinate nucleotide anabolism from tryptophan" EXACT [] +synonym: "nicotinate nucleotide formation from tryptophan" EXACT [] +synonym: "nicotinate nucleotide synthesis from tryptophan" EXACT [] +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0019357 ! nicotinate nucleotide biosynthetic process + +[Term] +id: GO:0019357 +name: nicotinate nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid)." [GOC:go_curators] +synonym: "nicotinate nucleotide anabolism" EXACT [] +synonym: "nicotinate nucleotide biosynthesis" EXACT [] +synonym: "nicotinate nucleotide formation" EXACT [] +synonym: "nicotinate nucleotide synthesis" EXACT [] +is_a: GO:0019363 ! pyridine nucleotide biosynthetic process +is_a: GO:0046497 ! nicotinate nucleotide metabolic process + +[Term] +id: GO:0019358 +name: nicotinate nucleotide salvage +namespace: biological_process +def: "The generation of nicotinate nucleotide without de novo synthesis." [GOC:go_curators] +synonym: "nicotinate nucleotide biosynthesis, salvage pathway" EXACT [] +synonym: "nicotinate nucleotide biosynthetic process, salvage pathway" EXACT [] +xref: MetaCyc:PWY-5381 +xref: MetaCyc:PYRIDNUCSAL-PWY +is_a: GO:0019357 ! nicotinate nucleotide biosynthetic process +is_a: GO:0019365 ! pyridine nucleotide salvage + +[Term] +id: GO:0019359 +name: nicotinamide nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide." [GOC:go_curators] +synonym: "nicotinamide nucleotide anabolism" EXACT [] +synonym: "nicotinamide nucleotide biosynthesis" EXACT [] +synonym: "nicotinamide nucleotide formation" EXACT [] +synonym: "nicotinamide nucleotide synthesis" EXACT [] +is_a: GO:0019363 ! pyridine nucleotide biosynthetic process +is_a: GO:0046496 ! nicotinamide nucleotide metabolic process + +[Term] +id: GO:0019360 +name: nicotinamide nucleotide biosynthetic process from niacinamide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide." [GOC:go_curators] +synonym: "nicotinamide nucleotide anabolism from niacinamide" EXACT [] +synonym: "nicotinamide nucleotide formation from niacinamide" EXACT [] +synonym: "nicotinamide nucleotide synthesis from niacinamide" EXACT [] +is_a: GO:0006769 ! nicotinamide metabolic process +is_a: GO:0019359 ! nicotinamide nucleotide biosynthetic process + +[Term] +id: GO:0019361 +name: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A." [GOC:ai] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA anabolism" EXACT [] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthesis" EXACT [] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA formation" EXACT [] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA synthesis" EXACT [] +xref: MetaCyc:P2-PWY +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0046432 ! 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process + +[Term] +id: GO:0019362 +name: pyridine nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base." [GOC:jl] +synonym: "pyridine nucleotide metabolism" EXACT [] +is_a: GO:0006733 ! oxidoreduction coenzyme metabolic process +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process + +[Term] +id: GO:0019363 +name: pyridine nucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base." [GOC:jl, GOC:pde, GOC:vw] +synonym: "pyridine nucleotide anabolism" EXACT [] +synonym: "pyridine nucleotide biosynthesis" EXACT [] +synonym: "pyridine nucleotide formation" EXACT [] +synonym: "pyridine nucleotide synthesis" EXACT [] +xref: MetaCyc:PYRIDNUCSYN-PWY +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0019362 ! pyridine nucleotide metabolic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process + +[Term] +id: GO:0019364 +name: pyridine nucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base." [GOC:jl, GOC:pde, GOC:vw] +synonym: "pyridine nucleotide breakdown" EXACT [] +synonym: "pyridine nucleotide catabolism" EXACT [] +synonym: "pyridine nucleotide degradation" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0019362 ! pyridine nucleotide metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process + +[Term] +id: GO:0019365 +name: pyridine nucleotide salvage +namespace: biological_process +def: "Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis." [GOC:jl] +synonym: "pyridine nucleotide cycling" EXACT [] +is_a: GO:0019363 ! pyridine nucleotide biosynthetic process +is_a: GO:0043173 ! nucleotide salvage + +[Term] +id: GO:0019367 +name: fatty acid elongation, saturated fatty acid +namespace: biological_process +def: "Elongation of a saturated fatty acid chain." [GOC:mah] +xref: MetaCyc:FASYN-ELONG-PWY +is_a: GO:0030497 ! fatty acid elongation + +[Term] +id: GO:0019368 +name: fatty acid elongation, unsaturated fatty acid +namespace: biological_process +def: "Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced." [GOC:mah] +xref: MetaCyc:PWY0-862 +is_a: GO:0030497 ! fatty acid elongation + +[Term] +id: GO:0019369 +name: arachidonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer." [ISBN:0198506732] +synonym: "arachidonic acid metabolism" EXACT [] +xref: Wikipedia:Arachidonic_acid +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0006690 ! icosanoid metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process + +[Term] +id: GO:0019370 +name: leukotriene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid." [GOC:go_curators] +synonym: "leukotriene anabolism" EXACT [] +synonym: "leukotriene biosynthesis" EXACT [] +synonym: "leukotriene formation" EXACT [] +synonym: "leukotriene synthesis" EXACT [] +xref: Wikipedia:Leukotriene#Leukotriene_synthesis +is_a: GO:0006691 ! leukotriene metabolic process +is_a: GO:0046456 ! icosanoid biosynthetic process + +[Term] +id: GO:0019371 +name: cyclooxygenase pathway +namespace: biological_process +def: "The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2." [PMID:19854273] +is_a: GO:0019369 ! arachidonic acid metabolic process +relationship: part_of GO:0001516 ! prostaglandin biosynthetic process + +[Term] +id: GO:0019372 +name: lipoxygenase pathway +namespace: biological_process +def: "The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase." [GOC:mah, PMID:17163881] +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0006690 ! icosanoid metabolic process + +[Term] +id: GO:0019373 +name: epoxygenase P450 pathway +namespace: biological_process +def: "The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids." [GOC:mah, PMID:17979511] +is_a: GO:0019369 ! arachidonic acid metabolic process + +[Term] +id: GO:0019374 +name: galactolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine." [ISBN:0198506732] +synonym: "galactolipid metabolism" EXACT [] +is_a: GO:0006664 ! glycolipid metabolic process + +[Term] +id: GO:0019375 +name: galactolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine." [ISBN:0198506732] +synonym: "galactolipid anabolism" EXACT [] +synonym: "galactolipid biosynthesis" EXACT [] +synonym: "galactolipid formation" EXACT [] +synonym: "galactolipid synthesis" EXACT [] +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0019374 ! galactolipid metabolic process + +[Term] +id: GO:0019376 +name: galactolipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine." [ISBN:0198506732] +synonym: "galactolipid breakdown" EXACT [] +synonym: "galactolipid catabolism" EXACT [] +synonym: "galactolipid degradation" EXACT [] +is_a: GO:0019374 ! galactolipid metabolic process +is_a: GO:0019377 ! glycolipid catabolic process + +[Term] +id: GO:0019377 +name: glycolipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)." [GOC:go_curators] +synonym: "glycolipid breakdown" EXACT [] +synonym: "glycolipid catabolism" EXACT [] +synonym: "glycolipid degradation" EXACT [] +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0046466 ! membrane lipid catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0019379 +name: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) +namespace: biological_process +def: "The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8)." [GOC:jl] +synonym: "sulphate assimilation, phosphoadenylyl sulphate reduction by a phosphoadenylyl-sulphate reductase (thioredoxin)" EXACT [] +xref: MetaCyc:SO4ASSIM-PWY +is_a: GO:0000103 ! sulfate assimilation +is_a: GO:0019419 ! sulfate reduction + +[Term] +id: GO:0019380 +name: 3-phenylpropionate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid." [GOC:ai] +synonym: "3-phenylpropionate breakdown" EXACT [] +synonym: "3-phenylpropionate catabolism" EXACT [] +synonym: "3-phenylpropionate degradation" EXACT [] +xref: MetaCyc:HCAMHPDEG-PWY +xref: MetaCyc:P281-PWY +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018962 ! 3-phenylpropionate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019381 +name: atrazine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide." [GOC:jl, UM-BBD_pathwayID:atr] +synonym: "atrazine breakdown" EXACT [] +synonym: "atrazine catabolism" EXACT [] +synonym: "atrazine degradation" EXACT [] +xref: MetaCyc:P141-PWY +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:0018873 ! atrazine metabolic process +is_a: GO:0042204 ! s-triazine compound catabolic process + +[Term] +id: GO:0019382 +name: carbon tetrachloride catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants." [GOC:go_curators] +synonym: "carbon tetrachloride breakdown" EXACT [] +synonym: "carbon tetrachloride catabolism" EXACT [] +synonym: "carbon tetrachloride degradation" EXACT [] +is_a: GO:0018885 ! carbon tetrachloride metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0019383 +name: (+)-camphor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone." [UM-BBD_pathwayID:cam] +synonym: "(+)-camphor breakdown" EXACT [] +synonym: "(+)-camphor catabolism" EXACT [] +synonym: "(+)-camphor degradation" EXACT [] +xref: MetaCyc:P601-PWY +is_a: GO:0016100 ! monoterpenoid catabolic process +is_a: GO:0018882 ! (+)-camphor metabolic process +is_a: GO:0042182 ! ketone catabolic process + +[Term] +id: GO:0019384 +name: caprolactam catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid." [GOC:curators] +synonym: "caprolactam breakdown" EXACT [] +synonym: "caprolactam catabolism" EXACT [] +synonym: "caprolactam degradation" EXACT [] +xref: MetaCyc:P621-PWY +is_a: GO:0018883 ! caprolactam metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072340 ! cellular lactam catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0019385 +name: methanogenesis, from acetate +namespace: biological_process +def: "The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate." [GOC:ai] +synonym: "methane biosynthesis from acetate" EXACT [] +synonym: "methane biosynthetic process from acetate" EXACT [] +xref: MetaCyc:METH-ACETATE-PWY +is_a: GO:0015948 ! methanogenesis + +[Term] +id: GO:0019386 +name: methanogenesis, from carbon dioxide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2)." [GOC:ai] +synonym: "methane biosynthesis from carbon dioxide" EXACT [] +synonym: "methane biosynthetic process from carbon dioxide" EXACT [] +xref: MetaCyc:METHANOGENESIS-PWY +is_a: GO:0015948 ! methanogenesis + +[Term] +id: GO:0019387 +name: methanogenesis, from methanol +namespace: biological_process +def: "The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol." [GOC:ai] +synonym: "methane biosynthesis from methanol" EXACT [] +synonym: "methane biosynthetic process from methanol" EXACT [] +xref: MetaCyc:METHFORM-PWY +is_a: GO:0015948 ! methanogenesis + +[Term] +id: GO:0019388 +name: galactose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose." [ISBN:0198506732] +synonym: "galactose breakdown" EXACT [] +synonym: "galactose catabolism" EXACT [] +synonym: "galactose degradation" EXACT [] +xref: MetaCyc:GALDEG-PWY +is_a: GO:0006012 ! galactose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0019389 +name: glucuronoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate." [ISBN:0198506732] +synonym: "glucuronide metabolic process" EXACT [] +synonym: "glucuronide metabolism" EXACT [] +synonym: "glucuronoside metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0019390 +name: glucuronoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue." [ISBN:0198506732] +synonym: "glucuronide biosynthesis" EXACT [] +synonym: "glucuronide biosynthetic process" EXACT [] +synonym: "glucuronoside anabolism" EXACT [] +synonym: "glucuronoside biosynthesis" EXACT [] +synonym: "glucuronoside formation" EXACT [] +synonym: "glucuronoside synthesis" EXACT [] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0019389 ! glucuronoside metabolic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0019391 +name: glucuronoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue." [ISBN:0198506732] +synonym: "glucuronide catabolic process" EXACT [] +synonym: "glucuronide catabolism" EXACT [] +synonym: "glucuronoside breakdown" EXACT [] +synonym: "glucuronoside catabolism" EXACT [] +synonym: "glucuronoside degradation" EXACT [] +xref: MetaCyc:GLUCUROCAT-PWY +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0019389 ! glucuronoside metabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0019392 +name: glucarate metabolic process +namespace: biological_process +alt_id: GO:0019581 +def: "The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate." [ISBN:0198506732] +synonym: "glucarate metabolism" EXACT [] +is_a: GO:0019577 ! aldaric acid metabolic process + +[Term] +id: GO:0019393 +name: glucarate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid." [ISBN:0198506732] +synonym: "glucarate anabolism" EXACT [] +synonym: "glucarate biosynthesis" EXACT [] +synonym: "glucarate formation" EXACT [] +synonym: "glucarate synthesis" EXACT [] +is_a: GO:0019392 ! glucarate metabolic process +is_a: GO:0019578 ! aldaric acid biosynthetic process + +[Term] +id: GO:0019394 +name: glucarate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid." [ISBN:0198506732] +synonym: "glucarate breakdown" EXACT [] +synonym: "glucarate catabolism" EXACT [] +synonym: "glucarate degradation" EXACT [] +xref: MetaCyc:GLUCARDEG-PWY +is_a: GO:0019392 ! glucarate metabolic process +is_a: GO:0019579 ! aldaric acid catabolic process + +[Term] +id: GO:0019395 +name: fatty acid oxidation +namespace: biological_process +def: "The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen." [ISBN:0198506732, MetaCyc:FAO-PWY] +xref: MetaCyc:FAO-PWY +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0034440 ! lipid oxidation + +[Term] +id: GO:0019396 +name: gallate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid)." [GOC:jl] +synonym: "gallate breakdown" EXACT [] +synonym: "gallate catabolism" EXACT [] +synonym: "gallate degradation" EXACT [] +synonym: "gallic acid catabolic process" EXACT [] +synonym: "gallic acid catabolism" EXACT [] +is_a: GO:0018918 ! gallate metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0019397 +name: gallate catabolic process via 2-pyrone-4,6-dicarboxylate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate." [GOC:jl] +synonym: "gallate breakdown via 2-pyrone-4,6-dicarboxylate" EXACT [] +synonym: "gallate degradation via 2-pyrone-4,6-dicarboxylate" EXACT [] +synonym: "gallic acid catabolic process via 2-pyrone-4,6-dicarboxylate" EXACT [] +synonym: "gallic acid catabolism via 2-pyrone-4,6-dicarboxylate" EXACT [] +xref: MetaCyc:GALLATE-DEGRADATION-I-PWY +is_a: GO:0042195 ! aerobic gallate catabolic process + +[Term] +id: GO:0019398 +name: gallate catabolic process via gallate dioxygenase activity +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase." [GOC:bf, GOC:jl] +synonym: "gallate breakdown via 4-carboxy-2-hydroxhexa-2,3-dienedioate" EXACT [] +synonym: "gallate catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate" BROAD [GOC:bf] +synonym: "gallate degradation via 4-carboxy-2-hydroxhexa-2,3-dienedioate" EXACT [] +synonym: "gallic acid catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate" EXACT [] +synonym: "gallic acid catabolism via 4-carboxy-2-hydroxhexa-2,3-dienedioate" EXACT [] +xref: MetaCyc:GALLATE-DEGRADATION-II-PWY +is_a: GO:0042195 ! aerobic gallate catabolic process +relationship: has_part GO:0036238 ! gallate dioxygenase activity + +[Term] +id: GO:0019399 +name: cyclohexanol oxidation +namespace: biological_process +def: "The cyclohexanol metabolic process in which cyclohexanol is converted to adipate." [MetaCyc:CYCLOHEXANOL-OXIDATION-PWY] +xref: MetaCyc:CYCLOHEXANOL-OXIDATION-PWY +is_a: GO:0018891 ! cyclohexanol metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019400 +name: alditol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group." [ISBN:0198506732] +synonym: "alditol metabolism" EXACT [] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0019401 +name: alditol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group." [ISBN:0198506732] +synonym: "alditol anabolism" EXACT [] +synonym: "alditol biosynthesis" EXACT [] +synonym: "alditol formation" EXACT [] +synonym: "alditol synthesis" EXACT [] +is_a: GO:0019400 ! alditol metabolic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process + +[Term] +id: GO:0019402 +name: galactitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [ISBN:0198506732] +synonym: "galactitol metabolism" EXACT [] +is_a: GO:0006059 ! hexitol metabolic process + +[Term] +id: GO:0019403 +name: galactitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [ISBN:0198506732] +synonym: "galactitol anabolism" EXACT [] +synonym: "galactitol biosynthesis" EXACT [] +synonym: "galactitol formation" EXACT [] +synonym: "galactitol synthesis" EXACT [] +is_a: GO:0019402 ! galactitol metabolic process +is_a: GO:0019406 ! hexitol biosynthetic process + +[Term] +id: GO:0019404 +name: galactitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [ISBN:0198506732] +synonym: "galactitol breakdown" EXACT [] +synonym: "galactitol catabolism" EXACT [] +synonym: "galactitol degradation" EXACT [] +xref: MetaCyc:GALACTITOLCAT-PWY +is_a: GO:0019402 ! galactitol metabolic process +is_a: GO:0019407 ! hexitol catabolic process + +[Term] +id: GO:0019405 +name: alditol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group." [ISBN:0198506732] +synonym: "alditol breakdown" EXACT [] +synonym: "alditol catabolism" EXACT [] +synonym: "alditol degradation" EXACT [] +is_a: GO:0019400 ! alditol metabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process +is_a: GO:0046174 ! polyol catabolic process + +[Term] +id: GO:0019406 +name: hexitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexitol anabolism" EXACT [] +synonym: "hexitol biosynthesis" EXACT [] +synonym: "hexitol formation" EXACT [] +synonym: "hexitol synthesis" EXACT [] +is_a: GO:0006059 ! hexitol metabolic process +is_a: GO:0019401 ! alditol biosynthetic process + +[Term] +id: GO:0019407 +name: hexitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule." [ISBN:0198506732] +synonym: "hexitol breakdown" EXACT [] +synonym: "hexitol catabolism" EXACT [] +synonym: "hexitol degradation" EXACT [] +is_a: GO:0006059 ! hexitol metabolic process +is_a: GO:0019405 ! alditol catabolic process + +[Term] +id: GO:0019408 +name: dolichol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units." [ISBN:0198506732] +synonym: "dolichol anabolism" EXACT [] +synonym: "dolichol biosynthesis" EXACT [] +synonym: "dolichol formation" EXACT [] +synonym: "dolichol synthesis" EXACT [] +is_a: GO:0016094 ! polyprenol biosynthetic process +is_a: GO:0019348 ! dolichol metabolic process + +[Term] +id: GO:0019409 +name: aerobic respiration, using ammonia as electron donor +namespace: biological_process +def: "The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite." [MetaCyc:AMMOXID-PWY] +synonym: "aerobic ammonia oxidation to nitrite via hydrazine" EXACT [GOC:mah] +xref: MetaCyc:AMMOXID-PWY +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds +is_a: GO:0019329 ! ammonia oxidation +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0019410 +name: aerobic respiration, using carbon monoxide as electron donor +namespace: biological_process +def: "The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation." [PMID:18024677] +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0019411 +name: aerobic respiration, using ferrous ions as electron donor +namespace: biological_process +def: "The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide." [ISBN:3131084111] +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0019412 +name: aerobic respiration, using hydrogen as electron donor +namespace: biological_process +def: "The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water." [MetaCyc:P283-PWY] +synonym: "hydrogen oxidation" BROAD [] +xref: MetaCyc:P283-PWY +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0019413 +name: acetate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] +synonym: "acetate anabolism" EXACT [] +synonym: "acetate biosynthesis" EXACT [] +synonym: "acetate formation" EXACT [] +synonym: "acetate synthesis" EXACT [] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0019414 +name: aerobic respiration, using sulfur or sulfate as electron donor +namespace: biological_process +def: "An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized." [PMID:11425697] +synonym: "aerobic respiration, using sulphur or sulphate as electron donor" EXACT [] +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0019415 +name: acetate biosynthetic process from carbon monoxide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide." [GOC:go_curators] +synonym: "acetate anabolism from carbon monoxide" EXACT [] +synonym: "acetate formation from carbon monoxide" EXACT [] +synonym: "acetate synthesis from carbon monoxide" EXACT [] +synonym: "carbon monoxide dehydrogenase pathway" EXACT [] +is_a: GO:0019413 ! acetate biosynthetic process +is_a: GO:0042133 ! neurotransmitter metabolic process + +[Term] +id: GO:0019416 +name: polythionate oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor." [MetaCyc:THIOSULFOX-PWY] +xref: MetaCyc:THIOSULFOX-PWY +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019417 +name: sulfur oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur." [GOC:jl, MetaCyc:FESULFOX-PWY, MetaCyc:SULFUROX-PWY] +synonym: "sulphur oxidation" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019418 +name: sulfide oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate." [MetaCyc:P222-PWY, MetaCyc:P223-PWY, MetaCyc:PWY-5274, MetaCyc:PWY-5285] +synonym: "sulphide oxidation" EXACT [] +xref: MetaCyc:P222-PWY +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019419 +name: sulfate reduction +namespace: biological_process +alt_id: GO:0019421 +def: "The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate." [MetaCyc:DISSULFRED-PWY, MetaCyc:P224-PWY, MetaCyc:SO4ASSIM-PWY, MetaCyc:SULFMETII-PWY] +synonym: "assimilatory sulfate reduction" NARROW [] +synonym: "assimilatory sulphate reduction" NARROW [] +synonym: "sulfate reduction, APS pathway" NARROW [] +synonym: "sulphate reduction" EXACT [] +synonym: "sulphate reduction, APS pathway" NARROW [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019420 +name: dissimilatory sulfate reduction +namespace: biological_process +def: "The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide." [GOC:jl, MetaCyc:DISSULFRED-PWY] +synonym: "dissimilatory sulphate reduction" EXACT [] +xref: MetaCyc:DISSULFRED-PWY +is_a: GO:0019419 ! sulfate reduction + +[Term] +id: GO:0019422 +name: disproportionation of elemental sulfur +namespace: biological_process +def: "The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2." [MetaCyc:P203-PWY] +synonym: "disproportionation of elemental sulphur" EXACT [] +xref: MetaCyc:P203-PWY +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0019423 +name: sulfur oxidation, ferric ion-dependent +namespace: biological_process +def: "A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+)." [MetaCyc:FESULFOX-PWY] +synonym: "sulphur oxidation, ferric ion-dependent" EXACT [] +xref: MetaCyc:FESULFOX-PWY +is_a: GO:0019417 ! sulfur oxidation + +[Term] +id: GO:0019424 +name: sulfide oxidation, using siroheme sulfite reductase +namespace: biological_process +alt_id: GO:0019425 +def: "A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase." [MetaCyc:P223-PWY] +synonym: "sulfide oxidation, using sirohaem sulfite reductase" EXACT [] +synonym: "sulfur oxidation, using sirohaem sulfite reductase" RELATED [] +synonym: "sulfur oxidation, using siroheme sulfite reductase" RELATED [] +synonym: "sulphide oxidation, using siroheme sulphite reductase" EXACT [] +synonym: "sulphur oxidation, using siroheme sulphite reductase" RELATED [] +xref: MetaCyc:P223-PWY +is_a: GO:0019418 ! sulfide oxidation + +[Term] +id: GO:0019426 +name: bisulfite reduction +namespace: biological_process +def: "The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite." [MetaCyc:P224-PWY] +synonym: "bisulphite reduction" EXACT [] +xref: MetaCyc:P224-PWY +is_a: GO:0019419 ! sulfate reduction + +[Term] +id: GO:0019427 +name: acetyl-CoA biosynthetic process from acetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate." [MetaCyc:ACETATEUTIL-PWY] +synonym: "acetate utilization" RELATED [] +synonym: "acetyl-CoA anabolism from acetate" EXACT [] +synonym: "acetyl-CoA formation from acetate" EXACT [] +synonym: "acetyl-CoA synthesis from acetate" EXACT [] +xref: MetaCyc:ACETATEUTIL-PWY +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0006085 ! acetyl-CoA biosynthetic process + +[Term] +id: GO:0019428 +name: allantoin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea." [GOC:go_curators] +synonym: "allantoin anabolism" EXACT [] +synonym: "allantoin biosynthesis" EXACT [] +synonym: "allantoin formation" EXACT [] +synonym: "allantoin synthesis" EXACT [] +xref: MetaCyc:URSIN-PWY +is_a: GO:0000255 ! allantoin metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0019429 +name: fluorene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents." [GOC:go_curators] +synonym: "fluorene breakdown" EXACT [] +synonym: "fluorene catabolism" EXACT [] +synonym: "fluorene degradation" EXACT [] +xref: MetaCyc:FLUORENE-DEG-9-ONE-PWY +is_a: GO:0018917 ! fluorene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019430 +name: removal of superoxide radicals +namespace: biological_process +def: "Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2)." [GOC:jl] +synonym: "cellular detoxification of superoxide radicals" EXACT [GOC:dos] +synonym: "removal of O2-" EXACT [] +synonym: "removal of oxygen free radicals" EXACT [] +xref: MetaCyc:DETOX1-PWY +is_a: GO:0006801 ! superoxide metabolic process +is_a: GO:0098869 ! cellular oxidant detoxification +relationship: part_of GO:0071451 ! cellular response to superoxide + +[Term] +id: GO:0019431 +name: acetyl-CoA biosynthetic process from ethanol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde." [GOC:go_curators] +synonym: "acetyl-CoA anabolism from ethanol" EXACT [] +synonym: "acetyl-CoA formation from ethanol" EXACT [] +synonym: "acetyl-CoA synthesis from ethanol" EXACT [] +xref: MetaCyc:ETOH-ACETYLCOA-ANA-PWY +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0006085 ! acetyl-CoA biosynthetic process + +[Term] +id: GO:0019432 +name: triglyceride biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol." [ISBN:0198506732] +synonym: "triacylglycerol biosynthesis" EXACT [] +synonym: "triacylglycerol biosynthetic process" EXACT [] +synonym: "triglyceride anabolism" EXACT [] +synonym: "triglyceride biosynthesis" EXACT [] +synonym: "triglyceride formation" EXACT [] +synonym: "triglyceride synthesis" EXACT [] +xref: MetaCyc:TRIGLSYN-PWY +is_a: GO:0006641 ! triglyceride metabolic process +is_a: GO:0046463 ! acylglycerol biosynthetic process + +[Term] +id: GO:0019433 +name: triglyceride catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol." [ISBN:0198506732] +synonym: "triacylglycerol catabolic process" EXACT [] +synonym: "triacylglycerol catabolism" EXACT [] +synonym: "triglyceride breakdown" EXACT [] +synonym: "triglyceride catabolism" EXACT [] +synonym: "triglyceride degradation" EXACT [] +xref: MetaCyc:LIPAS-PWY +is_a: GO:0006641 ! triglyceride metabolic process +is_a: GO:0046464 ! acylglycerol catabolic process + +[Term] +id: GO:0019434 +name: sophorosyloxydocosanoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon." [MetaCyc:DIGLUCODIACETYL-DOCOSANOATE] +synonym: "sophorosyloxydocosanoate metabolism" EXACT [] +is_a: GO:0006664 ! glycolipid metabolic process + +[Term] +id: GO:0019435 +name: sophorosyloxydocosanoate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate." [GOC:ai] +synonym: "sophorosyloxydocosanoate anabolism" EXACT [] +synonym: "sophorosyloxydocosanoate biosynthesis" EXACT [] +synonym: "sophorosyloxydocosanoate formation" EXACT [] +synonym: "sophorosyloxydocosanoate synthesis" EXACT [] +xref: MetaCyc:SOPHOROSYLOXYDOCOSANOATE-SYN-PWY +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0019434 ! sophorosyloxydocosanoate metabolic process + +[Term] +id: GO:0019436 +name: sophorosyloxydocosanoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate." [GOC:ai] +synonym: "sophorosyloxydocosanoate breakdown" EXACT [] +synonym: "sophorosyloxydocosanoate catabolism" EXACT [] +synonym: "sophorosyloxydocosanoate degradation" EXACT [] +xref: MetaCyc:SOPHOROSYLOXYDOCOSANOATE-DEG-PWY +is_a: GO:0019377 ! glycolipid catabolic process +is_a: GO:0019434 ! sophorosyloxydocosanoate metabolic process + +[Term] +id: GO:0019438 +name: aromatic compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] +synonym: "aromatic compound anabolism" EXACT [] +synonym: "aromatic compound biosynthesis" EXACT [] +synonym: "aromatic compound formation" EXACT [] +synonym: "aromatic compound synthesis" EXACT [] +synonym: "aromatic hydrocarbon biosynthesis" NARROW [] +synonym: "aromatic hydrocarbon biosynthetic process" NARROW [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0019439 +name: aromatic compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] +synonym: "aromatic compound breakdown" EXACT [] +synonym: "aromatic compound catabolism" EXACT [] +synonym: "aromatic compound degradation" EXACT [] +synonym: "aromatic hydrocarbon catabolic process" NARROW [] +synonym: "aromatic hydrocarbon catabolism" NARROW [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0019440 +name: tryptophan catabolic process to indole-3-acetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate." [GOC:go_curators] +synonym: "tryptophan breakdown to indole-3-acetate" EXACT [] +synonym: "tryptophan catabolic process to IAA" EXACT [] +synonym: "tryptophan catabolic process to indoleacetic acid" EXACT [] +synonym: "tryptophan catabolism to indoleacetic acid" EXACT [] +synonym: "tryptophan degradation to indole-3-acetate" EXACT [] +xref: MetaCyc:TRPIAACAT-PWY +is_a: GO:0006569 ! tryptophan catabolic process +is_a: GO:0009683 ! indoleacetic acid metabolic process + +[Term] +id: GO:0019441 +name: tryptophan catabolic process to kynurenine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine." [GOC:go_curators] +synonym: "tryptophan breakdown to kynurenine" EXACT [] +synonym: "tryptophan degradation to kynurenine" EXACT [] +xref: MetaCyc:TRPKYNCAT-PWY +is_a: GO:0006569 ! tryptophan catabolic process +is_a: GO:0070189 ! kynurenine metabolic process + +[Term] +id: GO:0019442 +name: tryptophan catabolic process to acetyl-CoA +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA." [GOC:go_curators] +synonym: "tryptophan breakdown to acetyl-CoA" EXACT [] +synonym: "tryptophan degradation to acetyl-CoA" EXACT [] +xref: MetaCyc:TRYPTOPHAN-DEGRADATION-1 +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0006569 ! tryptophan catabolic process + +[Term] +id: GO:0019443 +name: obsolete tryptophan catabolic process, using tryptophanase +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1)." [GOC:jl] +comment: This term was made obsolete because it refers to a one-step pathway. +synonym: "tryptophan breakdown, using tryptophanase" EXACT [] +synonym: "tryptophan catabolic process, using tryptophanase" EXACT [] +synonym: "tryptophan degradation, using tryptophanase" EXACT [] +is_obsolete: true +consider: GO:0006569 +consider: GO:0009034 + +[Term] +id: GO:0019444 +name: tryptophan catabolic process to catechol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol." [GOC:go_curators] +synonym: "tryptophan breakdown to catechol" EXACT [] +synonym: "tryptophan degradation to catechol" EXACT [] +xref: MetaCyc:TRPCAT-PWY +is_a: GO:0006569 ! tryptophan catabolic process +is_a: GO:0009712 ! catechol-containing compound metabolic process + +[Term] +id: GO:0019445 +name: tyrosine catabolic process to fumarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate." [GOC:go_curators] +synonym: "tyrosine breakdown to fumarate" EXACT [] +synonym: "tyrosine degradation to fumarate" EXACT [] +xref: MetaCyc:TYRFUMCAT-PWY +is_a: GO:0006106 ! fumarate metabolic process +is_a: GO:0006572 ! tyrosine catabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0019446 +name: obsolete tyrosine catabolic process to phosphoenolpyruvate +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate." [GOC:go_curators] +comment: The reason for obsoletion is that there is no evidence that this is a real process. +synonym: "tyrosine breakdown to phosphoenolpyruvate" EXACT [] +synonym: "tyrosine degradation to phosphoenolpyruvate" EXACT [] +is_obsolete: true + +[Term] +id: GO:0019447 +name: D-cysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin." [GOC:go_curators, ISBN:0198506732] +synonym: "D-cysteine breakdown" EXACT [] +synonym: "D-cysteine catabolism" EXACT [] +synonym: "D-cysteine degradation" EXACT [] +is_a: GO:0009093 ! cysteine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:0046438 ! D-cysteine metabolic process + +[Term] +id: GO:0019448 +name: L-cysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid." [GOC:jsg, GOC:mah] +synonym: "L-cysteine breakdown" EXACT [] +synonym: "L-cysteine catabolism" EXACT [] +synonym: "L-cysteine degradation" EXACT [] +is_a: GO:0009093 ! cysteine catabolic process +is_a: GO:0046439 ! L-cysteine metabolic process + +[Term] +id: GO:0019449 +name: L-cysteine catabolic process to hypotaurine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine." [GOC:go_curators] +synonym: "L-cysteine breakdown to hypotaurine" EXACT [] +synonym: "L-cysteine degradation to hypotaurine" EXACT [] +is_a: GO:0019448 ! L-cysteine catabolic process + +[Term] +id: GO:0019450 +name: L-cysteine catabolic process to pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate." [GOC:go_curators] +synonym: "L-cysteine breakdown to pyruvate" EXACT [] +synonym: "L-cysteine degradation to pyruvate" EXACT [] +xref: MetaCyc:LCYSDEG-PWY +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0019448 ! L-cysteine catabolic process + +[Term] +id: GO:0019451 +name: L-cysteine catabolic process to pyruvate, using cysteine dioxygenase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20)." [GOC:jl] +synonym: "L-cysteine breakdown to pyruvate, using cysteine dioxygenase" EXACT [] +synonym: "L-cysteine degradation to pyruvate, using cysteine dioxygenase" EXACT [] +xref: MetaCyc:CYSTEINE-DEG-PWY +is_a: GO:0019450 ! L-cysteine catabolic process to pyruvate + +[Term] +id: GO:0019452 +name: L-cysteine catabolic process to taurine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine." [GOC:go_curators] +synonym: "L-cysteine breakdown to taurine" EXACT [] +synonym: "L-cysteine degradation to taurine" EXACT [] +is_a: GO:0019448 ! L-cysteine catabolic process +is_a: GO:0019530 ! taurine metabolic process + +[Term] +id: GO:0019453 +name: L-cysteine catabolic process via cystine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine." [GOC:go_curators] +synonym: "L-cysteine breakdown via cystine" EXACT [] +synonym: "L-cysteine degradation via cystine" EXACT [] +is_a: GO:0019448 ! L-cysteine catabolic process + +[Term] +id: GO:0019454 +name: L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4)." [GOC:jl] +synonym: "L-cysteine breakdown via cystine, using glutathione-cystine transhydrogenase" EXACT [] +synonym: "L-cysteine degradation via cystine, using glutathione-cystine transhydrogenase" EXACT [] +is_a: GO:0019453 ! L-cysteine catabolic process via cystine + +[Term] +id: GO:0019455 +name: L-cysteine catabolic process via cystine, using cystine reductase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6)." [GOC:jl] +synonym: "L-cysteine breakdown via cystine, using cystine reductase" EXACT [] +synonym: "L-cysteine degradation via cystine, using cystine reductase" EXACT [] +is_a: GO:0019453 ! L-cysteine catabolic process via cystine + +[Term] +id: GO:0019456 +name: L-cysteine catabolic process via cystine, using cysteine transaminase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3)." [GOC:jl] +synonym: "L-cysteine breakdown via cystine, using cysteine transaminase" EXACT [] +synonym: "L-cysteine degradation via cystine, using cysteine transaminase" EXACT [] +is_a: GO:0019453 ! L-cysteine catabolic process via cystine + +[Term] +id: GO:0019457 +name: methionine catabolic process to succinyl-CoA +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA." [GOC:go_curators] +synonym: "methionine breakdown to succinyl-CoA" EXACT [] +synonym: "methionine degradation to succinyl-CoA" EXACT [] +xref: MetaCyc:METHIONINE-DEG1-PWY +is_a: GO:0006104 ! succinyl-CoA metabolic process +is_a: GO:0009087 ! methionine catabolic process + +[Term] +id: GO:0019458 +name: methionine catabolic process via 2-oxobutanoate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate." [GOC:go_curators] +synonym: "methionine breakdown via 2-oxobutanoate" EXACT [] +synonym: "methionine degradation via 2-oxobutanoate" EXACT [] +xref: MetaCyc:PWY-701 +is_a: GO:0009087 ! methionine catabolic process + +[Term] +id: GO:0019460 +name: glutamine catabolic process to fumarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate." [GOC:go_curators] +synonym: "glutamate catabolic process to fumarate" NARROW [GOC:bf, GOC:jl] +synonym: "glutamine breakdown to fumarate" EXACT [] +synonym: "glutamine degradation to fumarate" EXACT [] +is_a: GO:0006106 ! fumarate metabolic process +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0006543 ! glutamine catabolic process +relationship: has_part GO:0019550 ! glutamate catabolic process to aspartate + +[Term] +id: GO:0019461 +name: glutamine catabolic process to fumarate, using glutamate synthase (NADPH) +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13)." [GOC:bf, GOC:jl] +synonym: "glutamate catabolic process to fumarate, using glutamate synthase (NADPH)" RELATED [GOC:bf, GOC:jl] +synonym: "glutamine breakdown to fumarate, using glutamate synthase (NADPH)" EXACT [] +synonym: "glutamine degradation to fumarate, using glutamate synthase (NADPH)" EXACT [] +xref: MetaCyc:GLUTAMINEFUM-PWY +is_a: GO:0019460 ! glutamine catabolic process to fumarate +relationship: has_part GO:0004355 ! glutamate synthase (NADPH) activity + +[Term] +id: GO:0019462 +name: glutamine catabolic process to fumarate, using glutaminase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2)." [GOC:bf, GOC:jl] +synonym: "glutamate catabolic process to fumarate, using glutaminase" RELATED [GOC:bf, GOC:jl] +synonym: "glutamine breakdown to fumarate, using glutaminase" EXACT [] +synonym: "glutamine degradation to fumarate, using glutaminase" NARROW [] +xref: MetaCyc:GLUTAMINDEG-PWY +is_a: GO:0006538 ! glutamate catabolic process +relationship: has_part GO:0004359 ! glutaminase activity + +[Term] +id: GO:0019463 +name: glycine catabolic process to creatine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine." [GOC:go_curators] +synonym: "glycine breakdown to creatine" EXACT [] +synonym: "glycine degradation to creatine" EXACT [] +xref: MetaCyc:GLYCGREAT-PWY +is_a: GO:0006546 ! glycine catabolic process +is_a: GO:0006600 ! creatine metabolic process + +[Term] +id: GO:0019464 +name: glycine decarboxylation via glycine cleavage system +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex." [MetaCyc:GLYCLEAV-PWY] +synonym: "glycine cleavage system" BROAD [] +xref: MetaCyc:GLYCLEAV-PWY +is_a: GO:0006546 ! glycine catabolic process + +[Term] +id: GO:0019465 +name: aspartate transamidation +namespace: biological_process +def: "The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group." [GOC:go_curators, ISBN:0198506732] +xref: MetaCyc:ASPARTATE-DEG1-PWY +xref: MetaCyc:ASPARTATESYN-PWY +is_a: GO:0006533 ! aspartate catabolic process + +[Term] +id: GO:0019466 +name: ornithine catabolic process via proline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline." [GOC:go_curators] +synonym: "ornithine breakdown via proline" EXACT [] +synonym: "ornithine degradation via proline" EXACT [] +xref: MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY +is_a: GO:0006560 ! proline metabolic process +is_a: GO:0006593 ! ornithine catabolic process + +[Term] +id: GO:0019467 +name: ornithine catabolic process, by decarboxylation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation." [GOC:go_curators] +synonym: "ornithine breakdown, by decarboxylation" EXACT [] +synonym: "ornithine degradation, by decarboxylation" EXACT [] +xref: MetaCyc:ORNDEG-PWY +is_a: GO:0006593 ! ornithine catabolic process + +[Term] +id: GO:0019468 +name: nopaline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative." [GOC:jl, ISBN:0198506732] +synonym: "nopaline breakdown" EXACT [] +synonym: "nopaline catabolism" EXACT [] +synonym: "nopaline degradation" EXACT [] +xref: MetaCyc:NOPALINEDEG-PWY +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046418 ! nopaline metabolic process +is_a: GO:0072352 ! tricarboxylic acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019469 +name: octopine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine." [GOC:jl, ISBN:0198506732] +synonym: "octopine breakdown" EXACT [] +synonym: "octopine catabolism" EXACT [] +synonym: "octopine degradation" EXACT [] +xref: MetaCyc:OCTOPINEDEG-PWY +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:0046419 ! octopine metabolic process + +[Term] +id: GO:0019470 +name: 4-hydroxyproline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline." [GOC:ai] +synonym: "4-hydroxyproline breakdown" EXACT [] +synonym: "4-hydroxyproline catabolism" EXACT [] +synonym: "4-hydroxyproline degradation" EXACT [] +xref: MetaCyc:HYDROXYPRODEG-PWY +is_a: GO:0019471 ! 4-hydroxyproline metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019471 +name: 4-hydroxyproline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls." [GOC:ai] +synonym: "4-hydroxyproline metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0019472 +name: 4-hydroxyproline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline." [GOC:ai] +synonym: "4-hydroxyproline anabolism" EXACT [] +synonym: "4-hydroxyproline biosynthesis" EXACT [] +synonym: "4-hydroxyproline formation" EXACT [] +synonym: "4-hydroxyproline synthesis" EXACT [] +is_a: GO:0019471 ! 4-hydroxyproline metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0019473 +name: L-lysine catabolic process to glutarate, by acetylation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation." [GOC:go_curators] +synonym: "L-lysine breakdown to glutarate, by acetylation" EXACT [] +synonym: "L-lysine degradation to glutarate, by acetylation" EXACT [] +xref: MetaCyc:LYSDEGII-PWY +is_a: GO:0019477 ! L-lysine catabolic process + +[Term] +id: GO:0019474 +name: L-lysine catabolic process to acetyl-CoA +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA." [GOC:go_curators] +synonym: "L-lysine breakdown to acetyl-CoA" EXACT [] +synonym: "L-lysine degradation to acetyl-CoA" EXACT [] +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0019477 ! L-lysine catabolic process + +[Term] +id: GO:0019475 +name: L-lysine catabolic process to acetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate." [GOC:go_curators] +synonym: "L-lysine breakdown to acetate" EXACT [] +synonym: "L-lysine degradation to acetate" EXACT [] +synonym: "lysine fermentation" EXACT [] +xref: MetaCyc:P163-PWY +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0019477 ! L-lysine catabolic process +is_a: GO:0019665 ! anaerobic amino acid catabolic process + +[Term] +id: GO:0019476 +name: D-lysine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-lysine breakdown" EXACT [] +synonym: "D-lysine catabolism" EXACT [] +synonym: "D-lysine degradation" EXACT [] +is_a: GO:0006554 ! lysine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:0046441 ! D-lysine metabolic process + +[Term] +id: GO:0019477 +name: L-lysine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid." [GOC:go_curators, GOC:jsg, GOC:mah] +synonym: "L-lysine breakdown" EXACT [] +synonym: "L-lysine catabolism" EXACT [] +synonym: "L-lysine degradation" EXACT [] +is_a: GO:0006554 ! lysine catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046440 ! L-lysine metabolic process + +[Term] +id: GO:0019478 +name: D-amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids." [GOC:ai, GOC:jsg] +synonym: "D-amino acid breakdown" EXACT [] +synonym: "D-amino acid catabolism" EXACT [] +synonym: "D-amino acid degradation" EXACT [] +is_a: GO:0046416 ! D-amino acid metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019479 +name: L-alanine oxidation to D-lactate and ammonia +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia." [MetaCyc:ALACAT2-PWY] +xref: MetaCyc:ALACAT2-PWY +is_a: GO:0042853 ! L-alanine catabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019480 +name: L-alanine oxidation to pyruvate via D-alanine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate." [MetaCyc:ALADEG-PWY] +xref: MetaCyc:ALADEG-PWY +is_a: GO:0042853 ! L-alanine catabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019481 +name: L-alanine catabolic process, by transamination +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination." [GOC:go_curators] +synonym: "L-alanine breakdown, by transamination" EXACT [] +synonym: "L-alanine degradation, by transamination" EXACT [] +xref: MetaCyc:ALANINE-DEG3-PWY +is_a: GO:0042853 ! L-alanine catabolic process + +[Term] +id: GO:0019482 +name: beta-alanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins." [GOC:jl, ISBN:0198506732] +synonym: "beta-alanine metabolism" EXACT [] +xref: Wikipedia:Beta-alanine +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process + +[Term] +id: GO:0019483 +name: beta-alanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins." [GOC:jl, ISBN:0198506732] +synonym: "beta-alanine anabolism" EXACT [] +synonym: "beta-alanine biosynthesis" EXACT [] +synonym: "beta-alanine formation" EXACT [] +synonym: "beta-alanine synthesis" EXACT [] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0019482 ! beta-alanine metabolic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process + +[Term] +id: GO:0019484 +name: beta-alanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins." [GOC:jl, ISBN:0198506732] +synonym: "beta-alanine breakdown" EXACT [] +synonym: "beta-alanine catabolism" EXACT [] +synonym: "beta-alanine degradation" EXACT [] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0019482 ! beta-alanine metabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process + +[Term] +id: GO:0019485 +name: beta-alanine catabolic process to L-alanine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine." [GOC:go_curators] +synonym: "beta-alanine breakdown to L-alanine" EXACT [] +synonym: "beta-alanine degradation to L-alanine" EXACT [] +is_a: GO:0019484 ! beta-alanine catabolic process +is_a: GO:0042851 ! L-alanine metabolic process + +[Term] +id: GO:0019486 +name: beta-alanine catabolic process to mevalonate semialdehyde, by transamination +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination." [GOC:go_curators] +synonym: "beta-alanine breakdown to mevalonate semialdehyde, by transamination" EXACT [] +synonym: "beta-alanine degradation to mevalonate semialdehyde, by transamination" EXACT [] +xref: MetaCyc:BETA-ALA-DEGRADATION-I-PWY +is_a: GO:0019484 ! beta-alanine catabolic process + +[Term] +id: GO:0019487 +name: anaerobic acetylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen." [ISBN:0721662544] +synonym: "anaerobic acetylene breakdown" EXACT [] +synonym: "anaerobic acetylene catabolism" EXACT [] +synonym: "anaerobic acetylene degradation" EXACT [] +synonym: "anaerobic ethyne catabolic process" EXACT [] +synonym: "anaerobic ethyne catabolism" EXACT [] +xref: MetaCyc:P161-PWY +is_a: GO:0018864 ! acetylene metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0043454 ! alkyne catabolic process + +[Term] +id: GO:0019488 +name: ribitol catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate." [MetaCyc:RIBITOLUTIL-PWY] +synonym: "ribitol breakdown to xylulose 5-phosphate" EXACT [] +synonym: "ribitol degradation to xylulose 5-phosphate" EXACT [] +synonym: "ribitol utilization" RELATED [] +xref: MetaCyc:RIBITOLUTIL-PWY +is_a: GO:0046363 ! ribitol catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019489 +name: methylgallate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid." [GOC:ai] +synonym: "methylgallate metabolism" EXACT [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0019490 +name: 2-aminobenzenesulfonate desulfonation +namespace: biological_process +def: "The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [UM-BBD_pathwayID:abs] +synonym: "2-aminobenzenesulphonate desulphonation" EXACT [] +xref: MetaCyc:2ASDEG-PWY +is_a: GO:0018868 ! 2-aminobenzenesulfonate metabolic process + +[Term] +id: GO:0019491 +name: ectoine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria." [GOC:jl, PMID:11823218] +synonym: "ectoine anabolism" EXACT [] +synonym: "ectoine biosynthesis" EXACT [] +synonym: "ectoine formation" EXACT [] +synonym: "ectoine synthesis" EXACT [] +xref: MetaCyc:P101-PWY +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042399 ! ectoine metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0019492 +name: proline salvage +namespace: biological_process +def: "Any process which produces the amino acid proline from derivatives of it, without de novo synthesis." [GOC:jl] +synonym: "proline cycling" EXACT [] +is_a: GO:0006561 ! proline biosynthetic process +is_a: GO:0043102 ! amino acid salvage + +[Term] +id: GO:0019493 +name: arginine catabolic process to proline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline." [GOC:go_curators] +synonym: "arginine breakdown to proline" EXACT [] +synonym: "arginine degradation to proline" EXACT [] +xref: MetaCyc:ARG-PRO-PWY +is_a: GO:0006527 ! arginine catabolic process +is_a: GO:0006560 ! proline metabolic process + +[Term] +id: GO:0019495 +name: proline catabolic process to 2-oxoglutarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate." [GOC:go_curators] +synonym: "proline breakdown to 2-oxoglutarate" EXACT [] +synonym: "proline catabolic process to 2-ketoglutarate" EXACT [] +synonym: "proline catabolic process to alpha-ketoglutarate" EXACT [] +synonym: "proline catabolic process to alpha-oxoglutarate" EXACT [] +synonym: "proline catabolism to 2-ketoglutarate" EXACT [] +synonym: "proline catabolism to alpha-ketoglutarate" EXACT [] +synonym: "proline catabolism to alpha-oxoglutarate" EXACT [] +synonym: "proline degradation to 2-oxoglutarate" EXACT [] +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0006562 ! proline catabolic process + +[Term] +id: GO:0019496 +name: serine-isocitrate lyase pathway +namespace: biological_process +def: "A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide." [ISBN:0387961534] +is_a: GO:0006730 ! one-carbon metabolic process + +[Term] +id: GO:0019497 +name: hexachlorocyclohexane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution." [UM-BBD_pathwayID:ghch, UM-BBD_pathwayID:hch] +synonym: "hexachlorocyclohexane metabolism" EXACT [] +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process + +[Term] +id: GO:0019498 +name: n-octane oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA." [MetaCyc:P221-PWY] +xref: MetaCyc:P221-PWY +is_a: GO:0018939 ! n-octane metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019499 +name: cyanide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain." [ISBN:0198506732] +synonym: "cyanide metabolism" EXACT [] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0019500 +name: cyanide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration." [ISBN:0198506732] +synonym: "cyanide breakdown" EXACT [] +synonym: "cyanide catabolism" EXACT [] +synonym: "cyanide degradation" EXACT [] +xref: MetaCyc:P401-PWY +is_a: GO:0019499 ! cyanide metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0019501 +name: arsonoacetate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom." [GOC:jl] +synonym: "arsonoacetate breakdown" EXACT [] +synonym: "arsonoacetate catabolism" EXACT [] +synonym: "arsonoacetate degradation" EXACT [] +xref: MetaCyc:P482-PWY +is_a: GO:0018872 ! arsonoacetate metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0019502 +name: stachydrine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants." [GOC:curators, MetaCyc:CPD-821] +synonym: "stachydrine metabolism" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0019503 +name: stachydrine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline." [GOC:ai] +synonym: "stachydrine anabolism" EXACT [] +synonym: "stachydrine biosynthesis" EXACT [] +synonym: "stachydrine formation" EXACT [] +synonym: "stachydrine synthesis" EXACT [] +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0019502 ! stachydrine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0019504 +name: stachydrine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline." [GOC:ai] +synonym: "stachydrine breakdown" EXACT [] +synonym: "stachydrine catabolism" EXACT [] +synonym: "stachydrine degradation" EXACT [] +xref: MetaCyc:P561-PWY +is_a: GO:0006579 ! amino-acid betaine catabolic process +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0019502 ! stachydrine metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019505 +name: resorcinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic." [GOC:jl, http://www.speclab.com/compound/c108463.htm] +synonym: "1,3-benzenediol metabolic process" EXACT [] +synonym: "1,3-benzenediol metabolism" EXACT [] +synonym: "1,3-dihydroxybenzene metabolic process" EXACT [] +synonym: "1,3-dihydroxybenzene metabolism" EXACT [] +synonym: "resorcinol metabolism" EXACT [] +xref: MetaCyc:P343-PWY +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0019506 +name: phenylmercury acetate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group." [GOC:ai] +synonym: "phenylmercury acetate breakdown" EXACT [] +synonym: "phenylmercury acetate catabolism" EXACT [] +synonym: "phenylmercury acetate degradation" EXACT [] +xref: MetaCyc:P641-PWY +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046412 ! phenylmercury acetate metabolic process +is_a: GO:0046413 ! organomercury catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019507 +name: pyridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor." [GOC:curators] +synonym: "pyridine metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process + +[Term] +id: GO:0019508 +name: 2,5-dihydroxypyridine catabolic process to fumarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate." [MetaCyc:PWY-722] +synonym: "2,5-dihydroxypyridine breakdown to fumarate" EXACT [] +synonym: "2,5-dihydroxypyridine degradation to fumarate" EXACT [] +synonym: "2,5-dihydroxypyridine utilization" RELATED [] +synonym: "maleamate pathway" EXACT [] +synonym: "pyridine-2,5-diol catabolic process to fumarate" EXACT [] +xref: MetaCyc:PWY-722 +is_a: GO:0006106 ! fumarate metabolic process +is_a: GO:0051166 ! 2,5-dihydroxypyridine catabolic process + +[Term] +id: GO:0019509 +name: L-methionine salvage from methylthioadenosine +namespace: biological_process +def: "The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine." [GOC:jl, MetaCyc:PWY-4361] +synonym: "methionine recycling" NARROW [] +synonym: "methionine regeneration" NARROW [] +synonym: "methionine salvage from methylthioadenosine" EXACT [GOC:mah] +synonym: "methionine salvage pathway" EXACT [] +xref: MetaCyc:PWY-4361 +is_a: GO:0071267 ! L-methionine salvage + +[Term] +id: GO:0019510 +name: S-adenosylhomocysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine." [ISBN:0198506732] +synonym: "S-adenosylhomocysteine breakdown" EXACT [] +synonym: "S-adenosylhomocysteine catabolism" EXACT [] +synonym: "S-adenosylhomocysteine degradation" EXACT [] +xref: MetaCyc:ADENOSYLHOMOCYSCAT-PWY +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046130 ! purine ribonucleoside catabolic process +is_a: GO:0046498 ! S-adenosylhomocysteine metabolic process +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0019511 +name: peptidyl-proline hydroxylation +namespace: biological_process +alt_id: GO:0006472 +def: "The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline." [GOC:mah] +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0019512 +name: lactose catabolic process via tagatose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate." [GOC:go_curators] +synonym: "lactose breakdown via tagatose-6-phosphate" EXACT [] +synonym: "lactose degradation via tagatose-6-phosphate" EXACT [] +xref: MetaCyc:LACTOSECAT-PWY +is_a: GO:0005990 ! lactose catabolic process + +[Term] +id: GO:0019513 +name: lactose catabolic process, using glucoside 3-dehydrogenase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13)." [GOC:jl] +synonym: "lactose breakdown, using glucoside 3-dehydrogenase" EXACT [] +synonym: "lactose degradation, using glucoside 3-dehydrogenase" EXACT [] +xref: MetaCyc:LACTOSEUTIL-PWY +is_a: GO:0005990 ! lactose catabolic process + +[Term] +id: GO:0019514 +name: obsolete lactose hydrolysis +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because hydrolysis is a reaction. +synonym: "lactose hydrolysis" EXACT [] +is_obsolete: true +consider: GO:0004565 + +[Term] +id: GO:0019515 +name: lactose catabolic process via UDP-galactose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose." [GOC:go_curators] +synonym: "lactose breakdown via UDP-galactose" EXACT [] +synonym: "lactose degradation via UDP-galactose" EXACT [] +is_a: GO:0005990 ! lactose catabolic process + +[Term] +id: GO:0019516 +name: lactate oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons." [GOC:mah] +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019517 +name: L-threonine catabolic process to D-lactate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate." [GOC:bf, GOC:jl, MetaCyc:PWY-901, MetaCyc:THRDLCTCAT-PWY] +synonym: "L-threonine breakdown to D-lactate" EXACT [GOC:bf] +synonym: "L-threonine catabolic process to (R)-lactate" BROAD [GOC:bf] +synonym: "L-threonine catabolic process to methylglyoxal" EXACT [MetaCyc:THRDLCTCAT-PWY] +synonym: "L-threonine catabolic process to pyruvate" RELATED [GOC:bf, GOC:mah] +synonym: "L-threonine catabolism to D-lactate" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine degradation to D-lactate" EXACT [GOC:bf] +synonym: "threonine catabolic process to D-lactate" BROAD [GOC:bf] +xref: MetaCyc:THRDLCTCAT-PWY +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0006567 ! threonine catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0019518 +name: L-threonine catabolic process to glycine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine." [GOC:bf, GOC:mah, MetaCyc:THREONINE-DEG2-PWY] +synonym: "L-threonine breakdown to glycine" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine catabolic process to pyruvate" RELATED [GOC:bf, GOC:mah] +synonym: "L-threonine catabolism to glycine" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine degradation to glycine" EXACT [GOC:bf, GOC:mah] +synonym: "threonine catabolic process to glycine" BROAD [GOC:bf] +xref: MetaCyc:THREONINE-DEG2-PWY +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0006567 ! threonine catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0019519 +name: pentitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentitol metabolism" EXACT [] +is_a: GO:0019400 ! alditol metabolic process + +[Term] +id: GO:0019520 +name: aldonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group." [ISBN:0198506732] +synonym: "aldonic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0019521 +name: D-gluconate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "D-gluconate metabolism" EXACT [] +is_a: GO:0019520 ! aldonic acid metabolic process + +[Term] +id: GO:0019522 +name: ketogluconate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group." [ISBN:0198506732] +synonym: "ketogluconate metabolism" EXACT [] +xref: MetaCyc:KETOGLUCONMET-PWY +is_a: GO:0019520 ! aldonic acid metabolic process + +[Term] +id: GO:0019523 +name: L-idonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:ai] +synonym: "L-idonate metabolism" EXACT [] +xref: MetaCyc:IDNCAT-PWY +is_a: GO:0019520 ! aldonic acid metabolic process + +[Term] +id: GO:0019524 +name: keto-D-gluconate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "keto-D-gluconate breakdown" EXACT [] +synonym: "keto-D-gluconate catabolism" EXACT [] +synonym: "keto-D-gluconate degradation" EXACT [] +xref: MetaCyc:DHGLUCONATE-PYR-CAT-PWY +is_a: GO:0019525 ! keto-D-gluconate metabolic process +is_a: GO:0046181 ! ketogluconate catabolic process + +[Term] +id: GO:0019525 +name: keto-D-gluconate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "keto-D-gluconate metabolism" EXACT [] +is_a: GO:0019522 ! ketogluconate metabolic process + +[Term] +id: GO:0019526 +name: pentitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentitol anabolism" EXACT [] +synonym: "pentitol biosynthesis" EXACT [] +synonym: "pentitol formation" EXACT [] +synonym: "pentitol synthesis" EXACT [] +is_a: GO:0019401 ! alditol biosynthetic process +is_a: GO:0019519 ! pentitol metabolic process + +[Term] +id: GO:0019527 +name: pentitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentitol breakdown" EXACT [] +synonym: "pentitol catabolism" EXACT [] +synonym: "pentitol degradation" EXACT [] +is_a: GO:0019405 ! alditol catabolic process +is_a: GO:0019519 ! pentitol metabolic process + +[Term] +id: GO:0019528 +name: D-arabitol catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate." [MetaCyc:DARABITOLUTIL-PWY] +synonym: "D-arabitol breakdown to xylulose 5-phosphate" EXACT [] +synonym: "D-arabitol degradation" RELATED [] +synonym: "D-arabitol degradation to xylulose 5-phosphate" EXACT [] +synonym: "D-arabitol utilization" RELATED [] +xref: MetaCyc:DARABITOLUTIL-PWY +is_a: GO:0051159 ! D-arabitol catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019529 +name: taurine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats." [GOC:jl, ISBN:0198600461] +synonym: "taurine breakdown" EXACT [] +synonym: "taurine catabolism" EXACT [] +synonym: "taurine degradation" EXACT [] +xref: MetaCyc:TAURINEDEG-PWY +is_a: GO:0019530 ! taurine metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046306 ! alkanesulfonate catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0019530 +name: taurine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats." [GOC:jl, ISBN:0198600461] +synonym: "taurine metabolism" EXACT [] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0019694 ! alkanesulfonate metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0019531 +name: oxalate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals." [ISBN:0198506732] +synonym: "oxalic acid transporter activity" EXACT [] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:0019532 ! oxalate transport + +[Term] +id: GO:0019532 +name: oxalate transport +namespace: biological_process +def: "The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals." [ISBN:0198506732] +synonym: "ethanedioate transport" EXACT [] +synonym: "ethanedioic acid transport" EXACT [] +synonym: "oxalic acid transport" EXACT [] +is_a: GO:0006835 ! dicarboxylic acid transport + +[Term] +id: GO:0019533 +name: cellobiose transport +namespace: biological_process +def: "The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose." [GOC:ai] +is_a: GO:0015766 ! disaccharide transport + +[Term] +id: GO:0019534 +name: toxin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [ISBN:0198506732] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1901998 ! toxin transport + +[Term] +id: GO:0019535 +name: ferric-vibriobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other." [GOC:ai] +is_a: GO:0015603 ! iron chelate transmembrane transporter activity + +[Term] +id: GO:0019536 +name: vibriobactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae." [GOC:jl, PMID:11112537] +synonym: "vibriobactin metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0019537 +name: vibriobactin biosynthetic process +namespace: biological_process +alt_id: GO:0031195 +alt_id: GO:0031196 +def: "The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae." [GOC:jl, PMID:11112537] +synonym: "vibriobactin anabolism" EXACT [] +synonym: "vibriobactin biosynthesis" EXACT [] +synonym: "vibriobactin biosynthetic process, peptide formation" NARROW [] +synonym: "vibriobactin biosynthetic process, peptide modification" NARROW [] +synonym: "vibriobactin formation" EXACT [] +synonym: "vibriobactin synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0019536 ! vibriobactin metabolic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0019538 +name: protein metabolic process +namespace: biological_process +alt_id: GO:0006411 +alt_id: GO:0044268 +def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma] +subset: goslim_agr +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +synonym: "multicellular organismal protein metabolic process" NARROW [] +synonym: "protein metabolic process and modification" EXACT [] +synonym: "protein metabolism" EXACT [] +synonym: "protein metabolism and modification" EXACT [] +xref: Wikipedia:Protein_metabolism +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0044238 ! primary metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0019539 +name: siderophore biosynthetic process from hydroxamic acid +namespace: biological_process +alt_id: GO:0031197 +alt_id: GO:0031198 +def: "The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid." [GOC:go_curators] +synonym: "siderochrome biosynthesis from hydroxamic acid" NARROW [] +synonym: "siderochrome biosynthetic process from hydroxamic acid" NARROW [] +synonym: "siderophore anabolism from hydroxamic acid" EXACT [] +synonym: "siderophore biosynthetic process from hydroxamic acid, peptide formation" NARROW [] +synonym: "siderophore biosynthetic process from hydroxamic acid, peptide modification" NARROW [] +synonym: "siderophore formation from hydroxamic acid" EXACT [] +synonym: "siderophore synthesis from hydroxamic acid" EXACT [] +is_a: GO:0019290 ! siderophore biosynthetic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0019540 +name: siderophore biosynthetic process from catechol +namespace: biological_process +alt_id: GO:0031189 +alt_id: GO:0031190 +def: "The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol." [GOC:go_curators] +synonym: "siderochrome biosynthesis from catechol" NARROW [] +synonym: "siderochrome biosynthetic process from catechol" NARROW [] +synonym: "siderophore anabolism from catechol" EXACT [] +synonym: "siderophore biosynthetic process from catechol, peptide formation" NARROW [] +synonym: "siderophore biosynthetic process from catechol, peptide modification" NARROW [] +synonym: "siderophore formation from catechol" EXACT [] +synonym: "siderophore synthesis from catechol" EXACT [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0019290 ! siderophore biosynthetic process + +[Term] +id: GO:0019541 +name: propionate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants." [GOC:go_curators, ISBN:0198506732] +synonym: "propanoate metabolic process" EXACT [] +synonym: "propanoate metabolism" EXACT [] +synonym: "propionate metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0046459 ! short-chain fatty acid metabolic process + +[Term] +id: GO:0019542 +name: propionate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid." [GOC:go_curators] +synonym: "propionate anabolism" EXACT [] +synonym: "propionate biosynthesis" EXACT [] +synonym: "propionate formation" EXACT [] +synonym: "propionate synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0019541 ! propionate metabolic process +is_a: GO:0051790 ! short-chain fatty acid biosynthetic process + +[Term] +id: GO:0019543 +name: propionate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid." [GOC:go_curators] +synonym: "propionate breakdown" EXACT [] +synonym: "propionate catabolism" EXACT [] +synonym: "propionate degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019541 ! propionate metabolic process +is_a: GO:0019626 ! short-chain fatty acid catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0019544 +name: arginine catabolic process to glutamate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate." [GOC:go_curators] +synonym: "arginine breakdown to glutamate" EXACT [] +synonym: "arginine degradation to glutamate" EXACT [] +xref: MetaCyc:ARG-GLU-PWY +xref: MetaCyc:ARGASEDEG-PWY +is_a: GO:0006527 ! arginine catabolic process +is_a: GO:0006536 ! glutamate metabolic process + +[Term] +id: GO:0019545 +name: arginine catabolic process to succinate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate." [GOC:go_curators] +synonym: "arginine breakdown to succinate" EXACT [] +synonym: "arginine degradation to succinate" EXACT [] +xref: MetaCyc:ARGDEG-III-PWY +xref: MetaCyc:ARGDEG-IV-PWY +xref: MetaCyc:ARGDEG-V-PWY +xref: MetaCyc:AST-PWY +is_a: GO:0006105 ! succinate metabolic process +is_a: GO:0006527 ! arginine catabolic process + +[Term] +id: GO:0019546 +name: arginine deiminase pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase." [GOC:mah, MetaCyc:ARGDEGRAD-PWY] +xref: MetaCyc:ARGDEGRAD-PWY +is_a: GO:0006527 ! arginine catabolic process + +[Term] +id: GO:0019547 +name: arginine catabolic process to ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine." [GOC:go_curators] +synonym: "arginine breakdown to ornithine" EXACT [] +synonym: "arginine degradation to ornithine" EXACT [] +is_a: GO:0006527 ! arginine catabolic process +is_a: GO:0006591 ! ornithine metabolic process + +[Term] +id: GO:0019548 +name: arginine catabolic process to spermine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine." [GOC:go_curators] +synonym: "arginine breakdown to spermine" EXACT [] +synonym: "arginine degradation to spermine" EXACT [] +xref: MetaCyc:ARGSPECAT-PWY +is_a: GO:0006527 ! arginine catabolic process +is_a: GO:0008215 ! spermine metabolic process + +[Term] +id: GO:0019549 +name: glutamate catabolic process to succinate via succinate semialdehyde +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase." [GOC:bf, GOC:go_curators, MetaCyc:PWY-4321] +comment: While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants. +synonym: "glutamate breakdown to succinate" BROAD [] +synonym: "glutamate catabolic process to succinate via pyruvate-dependent GABA-transaminase activity" EXACT [] +synonym: "glutamate degradation to succinate" BROAD [] +xref: MetaCyc:PWY-4321 +is_a: GO:0006105 ! succinate metabolic process +is_a: GO:0006540 ! glutamate decarboxylation to succinate +relationship: has_part GO:0034387 ! 4-aminobutyrate:pyruvate transaminase activity + +[Term] +id: GO:0019550 +name: glutamate catabolic process to aspartate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate." [GOC:go_curators] +synonym: "glutamate breakdown to aspartate" EXACT [] +synonym: "glutamate degradation to aspartate" EXACT [] +xref: MetaCyc:GLUTDEG-PWY +is_a: GO:0006531 ! aspartate metabolic process +is_a: GO:0006538 ! glutamate catabolic process + +[Term] +id: GO:0019551 +name: glutamate catabolic process to 2-oxoglutarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate." [GOC:go_curators] +synonym: "glutamate breakdown to 2-oxoglutarate" EXACT [] +synonym: "glutamate catabolic process to 2-ketoglutarate" EXACT [] +synonym: "glutamate catabolic process to alpha-ketoglutarate" EXACT [] +synonym: "glutamate catabolic process to alpha-oxoglutarate" EXACT [] +synonym: "glutamate catabolism to 2-ketoglutarate" EXACT [] +synonym: "glutamate catabolism to alpha-ketoglutarate" EXACT [] +synonym: "glutamate catabolism to alpha-oxoglutarate" EXACT [] +synonym: "glutamate degradation to 2-oxoglutarate" EXACT [] +xref: MetaCyc:GLUTAMATE-DEG1-PWY +xref: MetaCyc:PWY-5766 +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0006106 ! fumarate metabolic process +is_a: GO:0006538 ! glutamate catabolic process + +[Term] +id: GO:0019552 +name: glutamate catabolic process via 2-hydroxyglutarate +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP." [MetaCyc:P162-PWY] +synonym: "glutamate fermentation via 2-hydroxyglutarate" EXACT [] +xref: MetaCyc:P162-PWY +is_a: GO:0019670 ! anaerobic glutamate catabolic process + +[Term] +id: GO:0019553 +name: glutamate catabolic process via L-citramalate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate." [GOC:go_curators] +synonym: "glutamate breakdown via L-citramalate" EXACT [] +synonym: "glutamate degradation via L-citramalate" EXACT [] +xref: MetaCyc:GLUDEG-II-PWY +is_a: GO:0006538 ! glutamate catabolic process + +[Term] +id: GO:0019554 +name: glutamate catabolic process to oxaloacetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate." [GOC:go_curators] +synonym: "glutamate breakdown to oxaloacetate" EXACT [] +synonym: "glutamate degradation to oxaloacetate" EXACT [] +is_a: GO:0006107 ! oxaloacetate metabolic process +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0019555 +name: glutamate catabolic process to ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine." [GOC:go_curators] +synonym: "glutamate breakdown to ornithine" EXACT [] +synonym: "glutamate degradation to ornithine" EXACT [] +xref: MetaCyc:GLUTORN-PWY +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0006591 ! ornithine metabolic process + +[Term] +id: GO:0019556 +name: histidine catabolic process to glutamate and formamide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide." [GOC:go_curators] +synonym: "histidine breakdown to glutamate and formamide" EXACT [] +synonym: "histidine degradation to glutamate and formamide" EXACT [] +xref: MetaCyc:HISDEG-PWY +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0006548 ! histidine catabolic process +is_a: GO:0043606 ! formamide metabolic process + +[Term] +id: GO:0019557 +name: histidine catabolic process to glutamate and formate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate." [GOC:go_curators] +synonym: "histidine breakdown to glutamate and formate" EXACT [] +synonym: "histidine degradation to glutamate and formate" EXACT [] +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0006548 ! histidine catabolic process +is_a: GO:0015942 ! formate metabolic process + +[Term] +id: GO:0019558 +name: histidine catabolic process to 2-oxoglutarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate." [GOC:go_curators] +synonym: "histidine breakdown to 2-oxoglutarate" EXACT [] +synonym: "histidine catabolic process to 2-ketoglutarate" EXACT [] +synonym: "histidine catabolic process to alpha-ketoglutarate" EXACT [] +synonym: "histidine catabolic process to alpha-oxoglutarate" EXACT [] +synonym: "histidine catabolism to 2-ketoglutarate" EXACT [] +synonym: "histidine catabolism to alpha-ketoglutarate" EXACT [] +synonym: "histidine catabolism to alpha-oxoglutarate" EXACT [] +synonym: "histidine degradation to 2-oxoglutarate" EXACT [] +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0006548 ! histidine catabolic process + +[Term] +id: GO:0019559 +name: histidine catabolic process to imidazol-5-yl-lactate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate." [GOC:go_curators] +synonym: "histidine breakdown to imidazol-5-yl-lactate" EXACT [] +synonym: "histidine degradation to imidazol-5-yl-lactate" EXACT [] +xref: MetaCyc:HISTDEG-PWY +is_a: GO:0006548 ! histidine catabolic process + +[Term] +id: GO:0019560 +name: histidine catabolic process to hydantoin-5-propionate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate." [GOC:go_curators] +synonym: "histidine breakdown to hydantoin-5-propionate" EXACT [] +synonym: "histidine degradation to hydantoin-5-propionate" EXACT [] +xref: MetaCyc:HISHP-PWY +is_a: GO:0006548 ! histidine catabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0019561 +name: anaerobic phenylalanine oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde." [GOC:mah, MetaCyc:ANAPHENOXI-PWY] +xref: MetaCyc:ANAPHENOXI-PWY +is_a: GO:0006559 ! L-phenylalanine catabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019562 +name: obsolete L-phenylalanine catabolic process to phosphoenolpyruvate +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate." [GOC:go_curators] +comment: The reason for obsoletion is that there is no evidence that this is a real process. +synonym: "phenylalanine breakdown to phosphoenolpyruvate" EXACT [] +synonym: "phenylalanine degradation to phosphoenolpyruvate" EXACT [] +xref: MetaCyc:PHENYLALANINE-DEG1-PWY +is_obsolete: true + +[Term] +id: GO:0019563 +name: glycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:go_curators, ISBN:0198506732] +synonym: "glycerol breakdown" EXACT [] +synonym: "glycerol catabolism" EXACT [] +synonym: "glycerol degradation" EXACT [] +xref: MetaCyc:PWY-4261 +xref: MetaCyc:PWY0-381 +is_a: GO:0006071 ! glycerol metabolic process +is_a: GO:0019405 ! alditol catabolic process + +[Term] +id: GO:0019564 +name: aerobic glycerol catabolic process +namespace: biological_process +alt_id: GO:0019565 +def: "The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen." [GOC:ai, ISBN:0198506732] +synonym: "aerobic glycerol breakdown" EXACT [] +synonym: "aerobic glycerol catabolism" EXACT [] +synonym: "aerobic glycerol degradation" EXACT [] +synonym: "aerobic glycerol fermentation" RELATED [] +xref: MetaCyc:PWY0-381 +is_a: GO:0019563 ! glycerol catabolic process + +[Term] +id: GO:0019566 +name: arabinose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides." [ISBN:0198506732] +synonym: "arabinose metabolism" EXACT [] +is_a: GO:0019321 ! pentose metabolic process + +[Term] +id: GO:0019567 +name: arabinose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose." [GOC:ai] +synonym: "arabinose anabolism" EXACT [] +synonym: "arabinose biosynthesis" EXACT [] +synonym: "arabinose formation" EXACT [] +synonym: "arabinose synthesis" EXACT [] +is_a: GO:0019322 ! pentose biosynthetic process +is_a: GO:0019566 ! arabinose metabolic process + +[Term] +id: GO:0019568 +name: arabinose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose." [GOC:ai] +synonym: "arabinose breakdown" EXACT [] +synonym: "arabinose catabolism" EXACT [] +synonym: "arabinose degradation" EXACT [] +is_a: GO:0019323 ! pentose catabolic process +is_a: GO:0019566 ! arabinose metabolic process + +[Term] +id: GO:0019569 +name: L-arabinose catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate." [GOC:go_curators] +synonym: "L-arabinose breakdown to xylulose 5-phosphate" EXACT [] +synonym: "L-arabinose degradation to xylulose 5-phosphate" EXACT [] +xref: MetaCyc:ARABCAT-PWY +is_a: GO:0019572 ! L-arabinose catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019570 +name: L-arabinose catabolic process to 2-oxoglutarate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate." [GOC:go_curators] +synonym: "L-arabinose breakdown to 2-oxoglutarate" EXACT [] +synonym: "L-arabinose catabolic process to 2-ketoglutarate" EXACT [] +synonym: "L-arabinose catabolic process to alpha-ketoglutarate" EXACT [] +synonym: "L-arabinose catabolic process to alpha-oxoglutarate" EXACT [] +synonym: "L-arabinose catabolism to 2-ketoglutarate" EXACT [] +synonym: "L-arabinose catabolism to alpha-ketoglutarate" EXACT [] +synonym: "L-arabinose catabolism to alpha-oxoglutarate" EXACT [] +synonym: "L-arabinose degradation to 2-oxoglutarate" EXACT [] +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0019572 ! L-arabinose catabolic process + +[Term] +id: GO:0019571 +name: D-arabinose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose." [GOC:jsg, GOC:mah] +synonym: "D-arabinose breakdown" EXACT [] +synonym: "D-arabinose catabolism" EXACT [] +synonym: "D-arabinose degradation" EXACT [] +is_a: GO:0019568 ! arabinose catabolic process +is_a: GO:0046372 ! D-arabinose metabolic process + +[Term] +id: GO:0019572 +name: L-arabinose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose." [GOC:jsg, GOC:mah] +synonym: "L-arabinose breakdown" EXACT [] +synonym: "L-arabinose catabolism" EXACT [] +synonym: "L-arabinose degradation" EXACT [] +is_a: GO:0019568 ! arabinose catabolic process +is_a: GO:0046373 ! L-arabinose metabolic process + +[Term] +id: GO:0019573 +name: D-arabinose catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate." [GOC:go_curators] +synonym: "D-arabinose breakdown to xylulose 5-phosphate" EXACT [] +synonym: "D-arabinose degradation to xylulose 5-phosphate" EXACT [] +xref: MetaCyc:DARABCAT-PWY +is_a: GO:0019571 ! D-arabinose catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019574 +name: sucrose catabolic process via 3'-ketosucrose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose." [GOC:bf, GOC:dgf, MetaCyc:SUCROSEUTIL2-PWY] +synonym: "sucrose breakdown, using glucoside 3-dehydrogenase" EXACT [] +synonym: "sucrose catabolic process to D-glucose" EXACT [GOC:bf, MetaCyc:SUCROSEUTIL2-PWY] +synonym: "sucrose catabolic process, using glucoside 3-dehydrogenase" EXACT [GOC:bf, MetaCyc:SUCROSEUTIL2-PWY] +synonym: "sucrose catabolism, using glucoside 3-dehydrogenase" EXACT [] +synonym: "sucrose degradation, using glucoside 3-dehydrogenase" EXACT [] +xref: MetaCyc:SUCROSEUTIL2-PWY +is_a: GO:0005987 ! sucrose catabolic process +is_a: GO:0006006 ! glucose metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +relationship: has_part GO:0008865 ! fructokinase activity +relationship: has_part GO:0048258 ! 3-ketoglucose-reductase activity + +[Term] +id: GO:0019575 +name: obsolete sucrose catabolic process, using beta-fructofuranosidase +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26)." [GOC:jl] +comment: This term was made obsolete because beta-fructofuranosidase (also known as invertase) catalyzes the first step in multiple routes of sucrose catabolism. +synonym: "sucrose breakdown, using beta-fructofuranosidase" EXACT [] +synonym: "sucrose catabolic process, using beta-fructofuranosidase" EXACT [] +synonym: "sucrose catabolism, using beta-fructofuranosidase" EXACT [] +synonym: "sucrose degradation, using beta-fructofuranosidase" EXACT [] +xref: MetaCyc:SUCUTIL-PWY +is_obsolete: true +consider: GO:0004564 +consider: GO:0036008 + +[Term] +id: GO:0019576 +name: aerobic fructose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen." [GOC:ai] +synonym: "aerobic fructose breakdown" EXACT [] +synonym: "aerobic fructose catabolism" EXACT [] +synonym: "aerobic fructose degradation" EXACT [] +is_a: GO:0006001 ! fructose catabolic process + +[Term] +id: GO:0019577 +name: aldaric acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group." [ISBN:0198506732] +synonym: "aldaric acid metabolism" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0019578 +name: aldaric acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group." [ISBN:0198506732] +synonym: "aldaric acid anabolism" EXACT [] +synonym: "aldaric acid biosynthesis" EXACT [] +synonym: "aldaric acid formation" EXACT [] +synonym: "aldaric acid synthesis" EXACT [] +is_a: GO:0016051 ! carbohydrate biosynthetic process +is_a: GO:0019577 ! aldaric acid metabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0019579 +name: aldaric acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group." [ISBN:0198506732] +synonym: "aldaric acid breakdown" EXACT [] +synonym: "aldaric acid catabolism" EXACT [] +synonym: "aldaric acid degradation" EXACT [] +is_a: GO:0016052 ! carbohydrate catabolic process +is_a: GO:0019577 ! aldaric acid metabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0019580 +name: galactarate metabolic process +namespace: biological_process +alt_id: GO:0046393 +def: "The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose." [GOC:pr, ISBN:0198506732] +synonym: "D-galactarate metabolic process" RELATED [] +synonym: "D-galactarate metabolism" RELATED [] +synonym: "galactarate metabolism" EXACT [] +synonym: "mucic acid metabolic process" EXACT [] +synonym: "mucic acid metabolism" EXACT [] +is_a: GO:0019577 ! aldaric acid metabolic process + +[Term] +id: GO:0019583 +name: galactonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose." [GOC:ai] +synonym: "galactonate metabolism" EXACT [] +is_a: GO:0019520 ! aldonic acid metabolic process + +[Term] +id: GO:0019584 +name: galactonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid." [GOC:ai] +synonym: "galactonate breakdown" EXACT [] +synonym: "galactonate catabolism" EXACT [] +synonym: "galactonate degradation" EXACT [] +xref: MetaCyc:GALACTCAT-PWY +is_a: GO:0019583 ! galactonate metabolic process +is_a: GO:0046176 ! aldonic acid catabolic process + +[Term] +id: GO:0019585 +name: glucuronate metabolic process +namespace: biological_process +alt_id: GO:0019699 +def: "The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:go_curators, ISBN:0198506732] +synonym: "glucuronate metabolism" EXACT [] +xref: Wikipedia:Glucuronic_acid +is_a: GO:0006063 ! uronic acid metabolic process + +[Term] +id: GO:0019586 +name: galacturonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [ISBN:0198506732] +synonym: "galacturonate metabolism" EXACT [] +is_a: GO:0006063 ! uronic acid metabolic process + +[Term] +id: GO:0019588 +name: anaerobic glycerol catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP." [GOC:mah] +synonym: "glycerol fermentation" EXACT [] +is_a: GO:0019563 ! glycerol catabolic process +is_a: GO:0019662 ! non-glycolytic fermentation +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0019589 +name: anaerobic glycerol catabolic process to propane-1,3-diol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water." [GOC:jl, MetaCyc:GOLPDLCAT-PWY] +synonym: "glycerol fermentation to 1,3-propanediol" EXACT [] +synonym: "glycerol fermentation to propane-1,3-diol" EXACT [] +xref: MetaCyc:GOLPDLCAT-PWY +is_a: GO:0019588 ! anaerobic glycerol catabolic process +is_a: GO:0051143 ! propanediol metabolic process + +[Term] +id: GO:0019590 +name: L-arabitol catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate." [MetaCyc:LARABITOLUTIL-PWY] +synonym: "L-arabitol and xylitol degradation" BROAD [] +synonym: "L-arabitol breakdown to xylulose 5-phosphate" EXACT [] +synonym: "L-arabitol degradation to xylulose 5-phosphate" EXACT [] +synonym: "L-arabitol utilization" RELATED [] +xref: MetaCyc:LARABITOLUTIL-PWY +is_a: GO:0051158 ! L-arabitol catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019592 +name: mannitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "mannitol breakdown" EXACT [] +synonym: "mannitol catabolism" EXACT [] +synonym: "mannitol degradation" EXACT [] +xref: MetaCyc:MANNIDEG-PWY +xref: MetaCyc:PWY-3861 +is_a: GO:0019407 ! hexitol catabolic process +is_a: GO:0019594 ! mannitol metabolic process + +[Term] +id: GO:0019593 +name: mannitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "mannitol anabolism" EXACT [] +synonym: "mannitol biosynthesis" EXACT [] +synonym: "mannitol formation" EXACT [] +synonym: "mannitol synthesis" EXACT [] +xref: MetaCyc:PWY-3881 +is_a: GO:0019406 ! hexitol biosynthetic process +is_a: GO:0019594 ! mannitol metabolic process + +[Term] +id: GO:0019594 +name: mannitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "mannitol metabolism" EXACT [] +is_a: GO:0006059 ! hexitol metabolic process + +[Term] +id: GO:0019595 +name: non-phosphorylated glucose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose." [GOC:ai] +synonym: "non-phosphorylated glucose breakdown" EXACT [] +synonym: "non-phosphorylated glucose catabolism" EXACT [] +synonym: "non-phosphorylated glucose degradation" EXACT [] +xref: MetaCyc:NPGLUCAT-PWY +is_a: GO:0006007 ! glucose catabolic process +is_a: GO:0046430 ! non-phosphorylated glucose metabolic process + +[Term] +id: GO:0019596 +name: mandelate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic." [GOC:go_curators] +synonym: "mandelate breakdown" EXACT [] +synonym: "mandelate catabolism" EXACT [] +synonym: "mandelate degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018924 ! mandelate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0019597 +name: (R)-mandelate catabolic process to benzoate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate." [GOC:go_curators] +synonym: "(R)-mandelate breakdown to benzoate" EXACT [] +synonym: "(R)-mandelate degradation to benzoate" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018874 ! benzoate metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0019596 ! mandelate catabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0019598 +name: (R)-mandelate catabolic process to catechol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol." [GOC:go_curators] +synonym: "(R)-mandelate breakdown to catechol" EXACT [] +synonym: "(R)-mandelate degradation to catechol" EXACT [] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0019596 ! mandelate catabolic process + +[Term] +id: GO:0019599 +name: (R)-4-hydroxymandelate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid." [GOC:ai] +synonym: "(R)-4-hydroxymandelate breakdown" EXACT [] +synonym: "(R)-4-hydroxymandelate catabolism" EXACT [] +synonym: "(R)-4-hydroxymandelate degradation" EXACT [] +xref: MetaCyc:4-HYDROXYMANDELATE-DEGRADATION-PWY +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0046431 ! (R)-4-hydroxymandelate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0019600 +name: toluene oxidation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene." [GOC:mah] +is_a: GO:0018970 ! toluene metabolic process +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0019601 +name: toluene oxidation via 2-hydroxytoluene +namespace: biological_process +def: "The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol)." [MetaCyc:TOLUENE-DEG-2-OH-PWY] +xref: MetaCyc:TOLUENE-DEG-2-OH-PWY +is_a: GO:0019600 ! toluene oxidation + +[Term] +id: GO:0019602 +name: toluene oxidation via 3-hydroxytoluene +namespace: biological_process +def: "The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol)." [MetaCyc:TOLUENE-DEG-3-OH-PWY] +xref: MetaCyc:TOLUENE-DEG-3-OH-PWY +is_a: GO:0019600 ! toluene oxidation + +[Term] +id: GO:0019603 +name: toluene oxidation via 4-hydroxytoluene +namespace: biological_process +def: "The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol)." [MetaCyc:TOLUENE-DEG-4-OH-PWY] +xref: MetaCyc:TOLUENE-DEG-4-OH-PWY +is_a: GO:0019600 ! toluene oxidation + +[Term] +id: GO:0019604 +name: toluene oxidation to catechol +namespace: biological_process +def: "The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2)." [MetaCyc:TOLUENE-DEG-CATECHOL-PWY] +xref: MetaCyc:TOLUENE-DEG-CATECHOL-PWY +xref: UM-BBD_pathwayID:tol +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0019600 ! toluene oxidation + +[Term] +id: GO:0019605 +name: butyrate metabolic process +namespace: biological_process +alt_id: GO:0043437 +def: "The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid." [ISBN:0198506732] +synonym: "butanoic acid metabolic process" EXACT [] +synonym: "butanoic acid metabolism" EXACT [] +synonym: "butyrate metabolism" EXACT [] +synonym: "butyric acid metabolic process" EXACT [] +synonym: "butyric acid metabolism" EXACT [] +is_a: GO:0046459 ! short-chain fatty acid metabolic process + +[Term] +id: GO:0019606 +name: 2-oxobutyrate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2." [ISBN:0198506732] +synonym: "2-oxobutyrate breakdown" EXACT [] +synonym: "2-oxobutyrate catabolism" EXACT [] +synonym: "2-oxobutyrate degradation" EXACT [] +synonym: "alpha-ketobutyrate catabolic process" EXACT [] +synonym: "alpha-ketobutyrate catabolism" EXACT [] +xref: MetaCyc:2OXOBUTYRATECAT-PWY +is_a: GO:0019626 ! short-chain fatty acid catabolic process +is_a: GO:0046361 ! 2-oxobutyrate metabolic process + +[Term] +id: GO:0019607 +name: phenylethylamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds." [GOC:jl, ISBN:0395825172] +synonym: "phenylethylamine breakdown" EXACT [] +synonym: "phenylethylamine catabolism" EXACT [] +synonym: "phenylethylamine degradation" EXACT [] +xref: MetaCyc:2PHENDEG-PWY +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:0042443 ! phenylethylamine metabolic process +is_a: GO:1901161 ! primary amino compound catabolic process + +[Term] +id: GO:0019608 +name: nicotine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine." [GOC:sm, ISBN:0198547684] +synonym: "nicotine breakdown" EXACT [] +synonym: "nicotine catabolism" EXACT [] +synonym: "nicotine degradation" EXACT [] +xref: MetaCyc:P181-PWY +xref: UM-BBD_pathwayID:nic +is_a: GO:0018933 ! nicotine metabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0019609 +name: 3-hydroxyphenylacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate." [http://chemfinder.cambridgesoft.com/] +synonym: "3-hydroxyphenylacetate metabolism" EXACT [] +synonym: "3HPA metabolic process" EXACT [] +synonym: "3HPA metabolism" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0019610 +name: 3-hydroxyphenylacetate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate." [http://chemfinder.cambridgesoft.com/] +synonym: "3-hydroxyphenylacetate breakdown" EXACT [] +synonym: "3-hydroxyphenylacetate catabolism" EXACT [] +synonym: "3-hydroxyphenylacetate degradation" EXACT [] +xref: MetaCyc:3-HYDROXYPHENYLACETATE-DEGRADATION-PWY +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0019609 ! 3-hydroxyphenylacetate metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0019611 +name: 4-toluenecarboxylate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule." [GOC:ai] +synonym: "4-toluenecarboxylate metabolism" EXACT [] +synonym: "p-toluate metabolic process" EXACT [] +synonym: "p-toluate metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0019612 +name: 4-toluenecarboxylate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule." [GOC:ai] +synonym: "4-toluenecarboxylate breakdown" EXACT [] +synonym: "4-toluenecarboxylate catabolism" EXACT [] +synonym: "4-toluenecarboxylate degradation" EXACT [] +synonym: "p-toluate catabolic process" EXACT [] +synonym: "p-toluate catabolism" EXACT [] +xref: MetaCyc:4TOLCARBDEG-PWY +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0019611 ! 4-toluenecarboxylate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019614 +name: catechol-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] +synonym: "catechol breakdown" RELATED [] +synonym: "catechol catabolic process" RELATED [] +synonym: "catechol catabolism" RELATED [] +synonym: "catechol degradation" RELATED [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process + +[Term] +id: GO:0019615 +name: catechol catabolic process, ortho-cleavage +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups." [GOC:jl, http://www.ence.umd.edu/] +synonym: "catechol breakdown, ortho-cleavage" EXACT [] +synonym: "catechol degradation, ortho-cleavage" EXACT [] +xref: MetaCyc:CATECHOL-ORTHO-CLEAVAGE-PWY +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0042952 ! beta-ketoadipate pathway + +[Term] +id: GO:0019616 +name: catechol catabolic process, meta-cleavage +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom." [GOC:jl, http://www.ence.umd.edu/] +synonym: "catechol breakdown, meta-cleavage" EXACT [] +synonym: "catechol degradation, meta-cleavage" EXACT [] +xref: MetaCyc:P183-PWY +is_a: GO:0019614 ! catechol-containing compound catabolic process + +[Term] +id: GO:0019617 +name: protocatechuate catabolic process, meta-cleavage +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate." [MetaCyc:P184-PWY] +synonym: "3,4-dihydroxybenzoate catabolic process, meta-cleavage" RELATED [] +synonym: "protocatechuate breakdown, meta-cleavage" EXACT [] +synonym: "protocatechuate catabolic process to oxaloacetate and pyruvate" EXACT [] +synonym: "protocatechuate degradation, meta-cleavage" EXACT [] +xref: MetaCyc:P184-PWY +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0006107 ! oxaloacetate metabolic process +is_a: GO:0019619 ! 3,4-dihydroxybenzoate catabolic process + +[Term] +id: GO:0019618 +name: protocatechuate catabolic process, ortho-cleavage +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate." [MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY] +synonym: "3,4-dihydroxybenzoate catabolic process, ortho-cleavage" EXACT [] +synonym: "protocatechuate breakdown, ortho-cleavage" EXACT [] +synonym: "protocatechuate catabolic process to beta-ketoadipate" EXACT [] +synonym: "protocatechuate degradation, ortho-cleavage" EXACT [] +xref: MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY +is_a: GO:0019619 ! 3,4-dihydroxybenzoate catabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0019619 +name: 3,4-dihydroxybenzoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate." [GOC:ai] +synonym: "protocatechuate breakdown" EXACT [] +synonym: "protocatechuate catabolic process" EXACT [] +synonym: "protocatechuate catabolism" EXACT [] +synonym: "protocatechuate degradation" EXACT [] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046278 ! 3,4-dihydroxybenzoate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0019620 +name: aerobic benzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen." [GOC:ai] +synonym: "aerobic benzoate metabolism" EXACT [] +is_a: GO:0018874 ! benzoate metabolic process + +[Term] +id: GO:0019621 +name: creatinine catabolic process to formate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate." [GOC:go_curators] +synonym: "creatinine breakdown to formate" EXACT [] +synonym: "creatinine degradation to formate" EXACT [] +xref: MetaCyc:CRNFORCAT-PWY +is_a: GO:0006602 ! creatinine catabolic process +is_a: GO:0015942 ! formate metabolic process + +[Term] +id: GO:0019622 +name: 3-(3-hydroxy)phenylpropionate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate." [GOC:ai] +synonym: "3-(3-hydroxy)phenylpropionate breakdown" EXACT [] +synonym: "3-(3-hydroxy)phenylpropionate catabolism" EXACT [] +synonym: "3-(3-hydroxy)phenylpropionate degradation" EXACT [] +xref: MetaCyc:HCAMHPDEG-PWY +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0046435 ! 3-(3-hydroxy)phenylpropionate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019623 +name: atrazine catabolic process to urea +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea." [GOC:jl] +synonym: "atrazine breakdown to urea" EXACT [] +synonym: "atrazine degradation to urea" EXACT [] +is_a: GO:0019381 ! atrazine catabolic process +is_a: GO:0019627 ! urea metabolic process + +[Term] +id: GO:0019624 +name: atrazine catabolic process to isopropylamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine." [GOC:jl] +synonym: "atrazine breakdown to isopropylamine" EXACT [] +synonym: "atrazine degradation to isopropylamine" EXACT [] +is_a: GO:0019381 ! atrazine catabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0019625 +name: atrazine catabolic process to cyanuric acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid." [GOC:jl] +synonym: "atrazine breakdown to cyanuric acid" EXACT [] +synonym: "atrazine degradation to cyanuric acid" EXACT [] +xref: MetaCyc:P141-PWY +is_a: GO:0019381 ! atrazine catabolic process +is_a: GO:0042199 ! cyanuric acid metabolic process + +[Term] +id: GO:0019626 +name: short-chain fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6." [ISBN:0198506732] +synonym: "short-chain fatty acid breakdown" EXACT [] +synonym: "short-chain fatty acid catabolism" EXACT [] +synonym: "short-chain fatty acid degradation" EXACT [] +xref: MetaCyc:ACETOACETATE-DEG-PWY +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0046459 ! short-chain fatty acid metabolic process + +[Term] +id: GO:0019627 +name: urea metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2." [ISBN:0198506732] +synonym: "urea metabolism" EXACT [] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0071941 ! nitrogen cycle metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0019628 +name: urate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine." [ISBN:0198506732] +synonym: "urate breakdown" EXACT [] +synonym: "urate catabolism" EXACT [] +synonym: "urate degradation" EXACT [] +synonym: "uric acid catabolic process" EXACT [] +xref: MetaCyc:P165-PWY +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:0046415 ! urate metabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0019629 +name: propionate catabolic process, 2-methylcitrate cycle +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle." [GOC:go_curators] +synonym: "propionate breakdown, 2-methylcitrate cycle" EXACT [] +synonym: "propionate degradation, 2-methylcitrate cycle" EXACT [] +is_a: GO:0019543 ! propionate catabolic process + +[Term] +id: GO:0019630 +name: quinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine." [GOC:jl, ISBN:0198506732] +synonym: "quinate metabolism" EXACT [] +synonym: "quinic acid metabolic process" EXACT [] +synonym: "quinic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0019631 +name: quinate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid." [GOC:jl] +synonym: "quinate breakdown" EXACT [] +synonym: "quinate catabolism" EXACT [] +synonym: "quinate degradation" EXACT [] +synonym: "quinic acid catabolic process" EXACT [] +synonym: "quinic acid catabolism" EXACT [] +xref: MetaCyc:QUINATEDEG-PWY +is_a: GO:0019630 ! quinate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0019632 +name: shikimate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids." [GOC:sm, ISBN:0198547684] +synonym: "shikimate metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0019633 +name: shikimate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid." [GOC:go_curators] +synonym: "shikimate breakdown" EXACT [] +synonym: "shikimate catabolism" EXACT [] +synonym: "shikimate degradation" EXACT [] +xref: MetaCyc:SHIKIMATEDEG-PWY +is_a: GO:0019632 ! shikimate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0019634 +name: organic phosphonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included." [GOC:js, ISBN:0721662544] +synonym: "organophosphonate metabolic process" RELATED [] +synonym: "phosphonate metabolism" EXACT [] +is_a: GO:0019637 ! organophosphate metabolic process + +[Term] +id: GO:0019635 +name: 2-aminoethylphosphonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine." [GOC:ai] +synonym: "2-aminoethylphosphonate breakdown" EXACT [] +synonym: "2-aminoethylphosphonate catabolism" EXACT [] +synonym: "2-aminoethylphosphonate degradation" EXACT [] +synonym: "2-phosphonoethylamine catabolic process" EXACT [] +synonym: "2-phosphonoethylamine catabolism" EXACT [] +synonym: "ciliatine catabolic process" EXACT [] +synonym: "ciliatine catabolism" EXACT [] +xref: MetaCyc:PHOSPHONOTASE-PWY +is_a: GO:0046433 ! 2-aminoethylphosphonate metabolic process +is_a: GO:1901161 ! primary amino compound catabolic process + +[Term] +id: GO:0019636 +name: phosphonoacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue." [MetaCyc:P483-PWY] +synonym: "phosphonoacetate metabolism" EXACT [] +xref: MetaCyc:P483-PWY +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0019637 +name: organophosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound." [ISBN:0198506732] +synonym: "organophosphate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0019638 +name: 6-hydroxycineole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2." [GOC:ai] +synonym: "6-endo-hydroxycineole metabolic process" EXACT [] +synonym: "6-endo-hydroxycineole metabolism" EXACT [] +synonym: "6-hydroxycineole metabolism" EXACT [] +synonym: "hydroxycineol metabolic process" EXACT [] +synonym: "hydroxycineol metabolism" EXACT [] +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0097176 ! epoxide metabolic process + +[Term] +id: GO:0019639 +name: 6-hydroxycineole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2." [GOC:ai] +synonym: "6-endo-hydroxycineole catabolic process" EXACT [] +synonym: "6-endo-hydroxycineole catabolism" EXACT [] +synonym: "6-hydroxycineole breakdown" EXACT [] +synonym: "6-hydroxycineole catabolism" EXACT [] +synonym: "6-hydroxycineole degradation" EXACT [] +synonym: "hydroxycineol catabolic process" EXACT [] +synonym: "hydroxycineol catabolism" EXACT [] +xref: MetaCyc:6-HYDROXYCINEOLE-DEGRADATION-PWY +is_a: GO:0016100 ! monoterpenoid catabolic process +is_a: GO:0019638 ! 6-hydroxycineole metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0019640 +name: glucuronate catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate." [GOC:go_curators] +synonym: "glucuronate breakdown to xylulose 5-phosphate" EXACT [] +synonym: "glucuronate degradation to xylulose 5-phosphate" EXACT [] +is_a: GO:0006064 ! glucuronate catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019643 +name: reductive tricarboxylic acid cycle +namespace: biological_process +alt_id: GO:0019644 +def: "A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate." [GOC:jl, PMID:15838028] +synonym: "reductive carboxylate cycle" EXACT [] +synonym: "reductive carboxylic acid cycle" EXACT [] +synonym: "reductive citric acid pathway" EXACT [] +synonym: "reductive Kreb's cycle" EXACT [] +synonym: "reductive TCA cycle" EXACT [] +xref: MetaCyc:P23-PWY +xref: MetaCyc:REDCITCYC +is_a: GO:0006099 ! tricarboxylic acid cycle +is_a: GO:0015977 ! carbon fixation + +[Term] +id: GO:0019645 +name: anaerobic electron transport chain +namespace: biological_process +def: "A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient." [GOC:ai, GOC:mtg_electron_transport] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0009061 ! anaerobic respiration + +[Term] +id: GO:0019646 +name: aerobic electron transport chain +namespace: biological_process +alt_id: GO:0006136 +alt_id: GO:0006137 +alt_id: GO:0006138 +def: "A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient." [GOC:ai, GOC:mtg_electron_transport] +synonym: "NADH-O2 electron transport" NARROW [] +synonym: "succinate-O2 electron transport" NARROW [] +synonym: "ubiquinone-8-O2 electron transport" NARROW [] +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0022904 ! respiratory electron transport chain + +[Term] +id: GO:0019647 +name: formaldehyde assimilation via ribulose monophosphate cycle +namespace: biological_process +def: "The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde." [MetaCyc:PWY-1861] +synonym: "formaldehyde assimilation via RuMP cycle" EXACT [] +synonym: "ribulose monophosphate cycle" BROAD [] +xref: MetaCyc:PWY-1861 +is_a: GO:0019649 ! formaldehyde assimilation + +[Term] +id: GO:0019648 +name: formaldehyde assimilation via xylulose monophosphate cycle +namespace: biological_process +def: "The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds." [MetaCyc:P185-PWY] +synonym: "formaldehyde assimilation via xylulose-5-phosphate cycle" EXACT [] +synonym: "formaldehyde fixation cycle" EXACT [] +xref: MetaCyc:P185-PWY +is_a: GO:0019649 ! formaldehyde assimilation +is_a: GO:0051167 ! xylulose 5-phosphate metabolic process + +[Term] +id: GO:0019649 +name: formaldehyde assimilation +namespace: biological_process +def: "The pathways in which formaldehyde is processed and used as a carbon source for the cell." [GOC:ai] +is_a: GO:0046292 ! formaldehyde metabolic process + +[Term] +id: GO:0019650 +name: glycolytic fermentation to butanediol +namespace: biological_process +alt_id: GO:0030646 +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia." [GOC:dph, GOC:nr, ISBN:0198506732] +synonym: "butanediol fermentation" EXACT [] +synonym: "glucose catabolic process to butanediol" EXACT [GOC:dph] +synonym: "glucose fermentation to butanediol" EXACT [] +xref: MetaCyc:P125-PWY +xref: Wikipedia:Butanediol_fermentation +is_a: GO:0019660 ! glycolytic fermentation +relationship: has_part GO:0003984 ! acetolactate synthase activity +relationship: has_part GO:0047605 ! acetolactate decarboxylase activity +relationship: has_part GO:0052587 ! diacetyl reductase ((R)-acetoin forming) activity + +[Term] +id: GO:0019651 +name: citrate catabolic process to diacetyl +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP." [MetaCyc:P126-PWY] +synonym: "citrate fermentation to diacetyl" EXACT [] +synonym: "diacetyl fermentation" EXACT [] +is_a: GO:0006101 ! citrate metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019662 ! non-glycolytic fermentation +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0072352 ! tricarboxylic acid catabolic process + +[Term] +id: GO:0019652 +name: lactate fermentation to propionate and acetate +namespace: biological_process +def: "The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl, MetaCyc:PROPFERM-PWY] +synonym: "acrylate pathway" EXACT [] +synonym: "nonrandomizing pathway" EXACT [] +synonym: "propionate fermentation" EXACT [] +xref: MetaCyc:PROPFERM-PWY +is_a: GO:0019541 ! propionate metabolic process +is_a: GO:0019662 ! non-glycolytic fermentation + +[Term] +id: GO:0019653 +name: anaerobic purine nucleobase catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP." [GOC:mah] +synonym: "anaerobic purine base catabolic process" EXACT [GOC:go_curators] +synonym: "anaerobic purine base catabolism" EXACT [] +synonym: "anaerobic purine catabolic process" RELATED [] +synonym: "purine base fermentation" EXACT [] +synonym: "purine fermentation" RELATED [] +xref: MetaCyc:P164-PWY +xref: MetaCyc:PWY-5044 +xref: MetaCyc:PWY-5497 +is_a: GO:0006145 ! purine nucleobase catabolic process +is_a: GO:0019666 ! nitrogenous compound fermentation + +[Term] +id: GO:0019654 +name: acetate fermentation +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP." [GOC:jl, MetaCyc:P142-PWY] +xref: MetaCyc:P142-PWY +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0006113 ! fermentation +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0019655 +name: glycolytic fermentation to ethanol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose." [GOC:dph, GOC:nr, ISBN:0716720094] +synonym: "alcoholic fermentation" RELATED [ISBN:0716720094] +synonym: "ethanol fermentation" EXACT [] +synonym: "glucose catabolic process to ethanol" EXACT [GOC:dph] +synonym: "glucose fermentation to ethanol" EXACT [] +xref: Wikipedia:Ethanol_fermentation +is_a: GO:0019660 ! glycolytic fermentation + +[Term] +id: GO:0019656 +name: glucose catabolic process to D-lactate and ethanol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule." [GOC:jl, MetaCyc:P122-PWY] +synonym: "glucose fermentation to D-lactate and ethanol" EXACT [] +synonym: "heterofermentation" EXACT [] +synonym: "heterofermentative lactate fermentation" EXACT [] +synonym: "heterofermentative pathway" EXACT [] +synonym: "heterolactate fermentation" EXACT [] +synonym: "heterolactic fermentation" EXACT [] +xref: MetaCyc:P122-PWY +is_a: GO:0019659 ! glucose catabolic process to lactate +is_a: GO:0019662 ! non-glycolytic fermentation +is_a: GO:1902707 ! hexose catabolic process to ethanol + +[Term] +id: GO:0019657 +name: glycolytic fermentation to propionate +namespace: biological_process +def: "Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate." [GOC:dph, GOC:nr, MetaCyc:P108-PWY] +synonym: "succinate-propionate fermentation" EXACT [] +xref: MetaCyc:P108-PWY +is_a: GO:0006105 ! succinate metabolic process +is_a: GO:0019541 ! propionate metabolic process +is_a: GO:0019660 ! glycolytic fermentation +is_a: GO:0042867 ! pyruvate catabolic process +relationship: has_part GO:0043821 ! propionyl-CoA:succinate CoA-transferase activity +relationship: has_part GO:0047154 ! methylmalonyl-CoA carboxytransferase activity + +[Term] +id: GO:0019658 +name: glucose fermentation to lactate and acetate +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP." [MetaCyc:P124-PWY] +synonym: "bifidum pathway" EXACT [] +synonym: "glucose catabolic process to lactate and acetate" BROAD [] +xref: MetaCyc:P124-PWY +is_a: GO:0006007 ! glucose catabolic process +is_a: GO:0019662 ! non-glycolytic fermentation + +[Term] +id: GO:0019659 +name: glucose catabolic process to lactate +namespace: biological_process +def: "The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl] +synonym: "glucose fermentation to lactate" EXACT [] +synonym: "lactate fermentation" EXACT [] +xref: Wikipedia:Lactic_acid_fermentation +is_a: GO:0006007 ! glucose catabolic process +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0006113 ! fermentation + +[Term] +id: GO:0019660 +name: glycolytic fermentation +namespace: biological_process +def: "Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:curators] +xref: MetaCyc:Pyruvate-Degredation +is_a: GO:0006113 ! fermentation +is_a: GO:0046034 ! ATP metabolic process + +[Term] +id: GO:0019661 +name: glucose catabolic process to lactate via pyruvate +namespace: biological_process +def: "The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP)." [GOC:jl] +synonym: "glucose fermentation to lactate via pyruvate" EXACT [] +synonym: "homofermentation" EXACT [] +synonym: "homofermentative lactate fermentation" EXACT [] +synonym: "homofermentative pathway" EXACT [] +synonym: "homolactate fermentation" EXACT [] +synonym: "homolactic fermentation" EXACT [ISBN:0716720094] +xref: MetaCyc:ANAEROFRUCAT-PWY +is_a: GO:0006734 ! NADH metabolic process +is_a: GO:0019659 ! glucose catabolic process to lactate +is_a: GO:0019660 ! glycolytic fermentation +is_a: GO:0019674 ! NAD metabolic process + +[Term] +id: GO:0019662 +name: non-glycolytic fermentation +namespace: biological_process +def: "Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:jl, MetaCyc:Fermentation] +is_a: GO:0006113 ! fermentation + +[Term] +id: GO:0019664 +name: mixed acid fermentation +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP." [ISBN:0716720094, MetaCyc:FERMENTATION-PWY] +synonym: "glucose catabolic process to mixed acids" BROAD [] +synonym: "glucose fermentation to mixed acids" EXACT [] +xref: Wikipedia:Mixed_acid_fermentation +is_a: GO:0019660 ! glycolytic fermentation + +[Term] +id: GO:0019665 +name: anaerobic amino acid catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP." [GOC:curators, GOC:jl, MetaCyc:Fermentation] +synonym: "amino acid fermentation" EXACT [] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0019666 ! nitrogenous compound fermentation + +[Term] +id: GO:0019666 +name: nitrogenous compound fermentation +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP." [GOC:mah] +synonym: "nitrogenous compound catabolic process" BROAD [] +is_a: GO:0006113 ! fermentation +is_a: GO:0006807 ! nitrogen compound metabolic process + +[Term] +id: GO:0019667 +name: anaerobic L-alanine catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP." [GOC:jl] +synonym: "L-alanine fermentation" EXACT [] +is_a: GO:0019665 ! anaerobic amino acid catabolic process + +[Term] +id: GO:0019668 +name: anaerobic catabolism of pairs of amino acids +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP." [GOC:mah, PMID:13140081] +synonym: "cofermentation of pairs of amino acids" EXACT [] +synonym: "Stickland reaction" NARROW [] +is_a: GO:0019665 ! anaerobic amino acid catabolic process + +[Term] +id: GO:0019669 +name: anaerobic glycine catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP." [GOC:jl] +synonym: "glycine fermentation" EXACT [] +is_a: GO:0019665 ! anaerobic amino acid catabolic process + +[Term] +id: GO:0019670 +name: anaerobic glutamate catabolic process +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP." [GOC:jl] +synonym: "glutamate fermentation" EXACT [] +is_a: GO:0019665 ! anaerobic amino acid catabolic process + +[Term] +id: GO:0019671 +name: glutamate catabolic process via mesaconate and citramalate +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP." [MetaCyc:GLUDEG-II-PWY] +synonym: "glutamate fermentation via mesaconate and citramalate" EXACT [] +xref: MetaCyc:GLUDEG-II-PWY +xref: MetaCyc:PWY-5087 +xref: MetaCyc:PWY-5088 +is_a: GO:0019670 ! anaerobic glutamate catabolic process + +[Term] +id: GO:0019672 +name: ethanol-acetate fermentation to butyrate and caproate +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP." [MetaCyc:P127-PWY] +is_a: GO:0019662 ! non-glycolytic fermentation + +[Term] +id: GO:0019673 +name: GDP-mannose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-mannose metabolism" EXACT [] +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0019674 +name: NAD metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid." [GOC:jl, ISBN:0618254153] +synonym: "NAD (oxidized) metabolic process" EXACT [] +synonym: "NAD (oxidized) metabolism" EXACT [] +synonym: "NAD metabolism" EXACT [] +synonym: "NAD phosphorylation and dephosphorylation" NARROW [] +synonym: "nicotinamide adenine dinucleotide metabolic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide metabolism" EXACT [] +synonym: "oxidized NAD metabolic process" EXACT [] +synonym: "oxidized NAD metabolism" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0019675 +name: obsolete NAD phosphorylation and dephosphorylation +namespace: biological_process +def: "OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid." [GOC:jl, ISBN:0618254153] +comment: This term was made obsolete because it represents a process, NAD dephosphorylation, that does not exist. +synonym: "NAD phosphorylation and dephosphorylation" EXACT [] +synonym: "nicotinamide adenine dinucleotide phosphorylation and dephosphorylation" EXACT [] +is_obsolete: true +consider: GO:0006739 +consider: GO:0019674 + +[Term] +id: GO:0019676 +name: ammonia assimilation cycle +namespace: biological_process +def: "The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen." [MetaCyc:AMMASSIM-PWY] +synonym: "glutamate metabolic process via glutamine and ammonia" EXACT [] +synonym: "glutamate metabolism via glutamine and ammonia" EXACT [] +xref: MetaCyc:AMMASSIM-PWY +xref: MetaCyc:PWY-3282 +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0006541 ! glutamine metabolic process +is_a: GO:0019740 ! nitrogen utilization + +[Term] +id: GO:0019677 +name: NAD catabolic process +namespace: biological_process +alt_id: GO:0006737 +def: "The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:jl, ISBN:0618254153] +synonym: "NAD (oxidized) catabolic process" EXACT [] +synonym: "NAD (oxidized) catabolism" EXACT [] +synonym: "NAD (reduced) catabolic process" EXACT [] +synonym: "NAD (reduced) catabolism" EXACT [] +synonym: "NAD breakdown" EXACT [] +synonym: "NAD catabolism" EXACT [] +synonym: "NAD degradation" EXACT [] +synonym: "NADH catabolic process" EXACT [] +synonym: "NADH catabolism" EXACT [] +synonym: "nicotinamide adenine dinucleotide catabolic process" EXACT [] +synonym: "nicotinamide adenine dinucleotide catabolism" EXACT [] +synonym: "oxidized NAD catabolic process" EXACT [] +synonym: "oxidized NAD catabolism" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide catabolic process" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide catabolism" EXACT [] +synonym: "reduced NAD catabolic process" EXACT [] +synonym: "reduced NAD catabolism" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide catabolic process" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide catabolism" EXACT [] +is_a: GO:0019364 ! pyridine nucleotide catabolic process +is_a: GO:0046496 ! nicotinamide nucleotide metabolic process + +[Term] +id: GO:0019678 +name: propionate metabolic process, methylmalonyl pathway +namespace: biological_process +def: "The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway." [GOC:go_curators] +synonym: "propionate metabolism, methylmalonyl pathway" EXACT [] +xref: MetaCyc:PROPIONMET-PWY +is_a: GO:0019541 ! propionate metabolic process + +[Term] +id: GO:0019679 +name: propionate metabolic process, methylcitrate cycle +namespace: biological_process +def: "The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle." [GOC:go_curators] +synonym: "propionate metabolism, methylcitrate cycle" EXACT [] +xref: MetaCyc:PWY0-42 +is_a: GO:0019541 ! propionate metabolic process + +[Term] +id: GO:0019680 +name: L-methylmalonyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-methylmalonyl-CoA anabolism" EXACT [] +synonym: "L-methylmalonyl-CoA biosynthesis" EXACT [] +synonym: "L-methylmalonyl-CoA formation" EXACT [] +synonym: "L-methylmalonyl-CoA synthesis" EXACT [] +xref: MetaCyc:PWY0-43 +is_a: GO:0046491 ! L-methylmalonyl-CoA metabolic process +is_a: GO:0071616 ! acyl-CoA biosynthetic process + +[Term] +id: GO:0019681 +name: acetyl-CoA assimilation pathway +namespace: biological_process +def: "The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell." [MetaCyc:P22-PWY] +synonym: "acetyl-CoA catabolic process to 2-ketoglutarate" EXACT [] +synonym: "acetyl-CoA catabolic process to 2-oxoglutarate" EXACT [] +synonym: "acetyl-CoA catabolic process to alpha-ketoglutarate" EXACT [] +synonym: "acetyl-CoA catabolic process to alpha-oxoglutarate" EXACT [] +synonym: "acetyl-CoA catabolism to 2-ketoglutarate" EXACT [] +synonym: "acetyl-CoA catabolism to 2-oxoglutarate" EXACT [] +synonym: "acetyl-CoA catabolism to alpha-ketoglutarate" EXACT [] +synonym: "acetyl-CoA catabolism to alpha-oxoglutarate" EXACT [] +is_a: GO:0006103 ! 2-oxoglutarate metabolic process +is_a: GO:0046356 ! acetyl-CoA catabolic process + +[Term] +id: GO:0019682 +name: glyceraldehyde-3-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis." [GOC:ai, ISBN:0198506732] +synonym: "glyceraldehyde 3-phosphate metabolic process" EXACT [] +synonym: "glyceraldehyde 3-phosphate metabolism" EXACT [] +synonym: "glyceraldehyde-3-phosphate metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0019683 +name: glyceraldehyde-3-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis." [ISBN:0198506732] +synonym: "glyceraldehyde 3-phosphate catabolic process" EXACT [] +synonym: "glyceraldehyde 3-phosphate catabolism" EXACT [] +synonym: "glyceraldehyde-3-phosphate breakdown" EXACT [] +synonym: "glyceraldehyde-3-phosphate catabolism" EXACT [] +synonym: "glyceraldehyde-3-phosphate degradation" EXACT [] +is_a: GO:0019682 ! glyceraldehyde-3-phosphate metabolic process +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0019684 +name: photosynthesis, light reaction +namespace: biological_process +def: "The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I." [http://www.arabidopsis.org] +synonym: "photolysis" RELATED [] +xref: MetaCyc:PWY-101 +xref: Wikipedia:Photolysis#Photolysis_in_photosynthesis +is_a: GO:0006091 ! generation of precursor metabolites and energy +relationship: part_of GO:0015979 ! photosynthesis + +[Term] +id: GO:0019685 +name: photosynthesis, dark reaction +namespace: biological_process +def: "A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions." [ISBN:0582015952] +is_a: GO:0016051 ! carbohydrate biosynthetic process +relationship: part_of GO:0015979 ! photosynthesis + +[Term] +id: GO:0019686 +name: purine nucleoside interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0015949 ! nucleobase-containing small molecule interconversion +is_a: GO:0042278 ! purine nucleoside metabolic process + +[Term] +id: GO:0019687 +name: pyruvate biosynthetic process from acetate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate." [GOC:go_curators] +synonym: "pyruvate anabolism from acetate" EXACT [] +synonym: "pyruvate formation from acetate" EXACT [] +synonym: "pyruvate synthesis from acetate" EXACT [] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0042866 ! pyruvate biosynthetic process + +[Term] +id: GO:0019688 +name: purine deoxyribonucleoside interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0019686 ! purine nucleoside interconversion +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0019689 +name: pyrimidine nucleoside interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0015949 ! nucleobase-containing small molecule interconversion + +[Term] +id: GO:0019690 +name: pyrimidine deoxyribonucleoside interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside." [GOC:mah, ISBN:0306444747, ISBN:0471394831] +is_a: GO:0019689 ! pyrimidine nucleoside interconversion +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process + +[Term] +id: GO:0019692 +name: deoxyribose phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose." [ISBN:0198506732] +synonym: "deoxyribose phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0019693 +name: ribose phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar." [GOC:ai] +synonym: "ribose phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0019694 +name: alkanesulfonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group." [GOC:ai] +synonym: "alkanesulfonate metabolism" EXACT [] +synonym: "alkanesulphonate metabolic process" EXACT [] +synonym: "alkanesulphonate metabolism" EXACT [] +xref: MetaCyc:ALKANEMONOX-PWY +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0019695 +name: choline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:jl, ISBN:0192801023] +synonym: "choline metabolism" EXACT [] +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0071704 ! organic substance metabolic process +is_a: GO:0097164 ! ammonium ion metabolic process + +[Term] +id: GO:0019696 +name: toluene oxidation via toluene-cis-1,2-dihydrodiol +namespace: biological_process +def: "The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol." [MetaCyc:TOLUENE-DEG-DIOL-PWY] +xref: MetaCyc:TOLUENE-DEG-DIOL-PWY +is_a: GO:0019600 ! toluene oxidation + +[Term] +id: GO:0019697 +name: L-xylitol catabolic process to xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate." [MetaCyc:LARABITOLUTIL-PWY] +synonym: "L-arabitol and xylitol degradation" BROAD [] +synonym: "L-xylitol breakdown to xylulose 5-phosphate" EXACT [] +synonym: "L-xylitol degradation to xylulose 5-phosphate" EXACT [] +synonym: "L-xylitol utilization" RELATED [] +xref: MetaCyc:LARABITOLUTIL-PWY +is_a: GO:0051160 ! L-xylitol catabolic process +is_a: GO:1901159 ! xylulose 5-phosphate biosynthetic process + +[Term] +id: GO:0019698 +name: D-galacturonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-galacturonate breakdown" EXACT [] +synonym: "D-galacturonate catabolism" EXACT [] +synonym: "D-galacturonate degradation" EXACT [] +xref: MetaCyc:GALACTUROCAT-PWY +is_a: GO:0046396 ! D-galacturonate metabolic process +is_a: GO:0046397 ! galacturonate catabolic process + +[Term] +id: GO:0019700 +name: organic phosphonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included." [GOC:js] +synonym: "organophosphonate catabolic process" RELATED [] +synonym: "phosphonate breakdown" EXACT [] +synonym: "phosphonate catabolism" EXACT [] +synonym: "phosphonate degradation" EXACT [] +is_a: GO:0019634 ! organic phosphonate metabolic process +is_a: GO:0046434 ! organophosphate catabolic process + +[Term] +id: GO:0019701 +name: peptidyl-arginine N5-methylation +namespace: biological_process +def: "The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine." [GOC:bf, PMID:9792625, RESID:AA0305] +synonym: "peptidyl-arginine delta-N-methylation" EXACT [] +xref: RESID:AA0305 +is_a: GO:0035246 ! peptidyl-arginine N-methylation + +[Term] +id: GO:0019702 +name: protein-arginine N5-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine." [EC:2.1.1.322, PMID:9873020] +comment: This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are Arg67 of the ribosomal protein L12. +synonym: "protein-arginine delta-N-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)" EXACT [EC:2.1.1.322] +synonym: "type IV PRMT activity" EXACT [] +synonym: "type IV protein arginine methyltransferase activity" EXACT [] +xref: EC:2.1.1.322 +xref: RHEA:48116 +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity + +[Term] +id: GO:0019703 +name: coenzyme A-peptidyl-cysteine covalent linking +namespace: biological_process +def: "The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide." [RESID:AA0306] +xref: RESID:AA0306 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0019704 +name: peptidyl-L-cysteine S-myristoylation +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine." [RESID:AA0307] +synonym: "peptidyl-S-myristoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-myristoyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-myristoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0307 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018377 ! protein myristoylation + +[Term] +id: GO:0019705 +name: protein-cysteine S-myristoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein]." [GOC:ai, PMID:22247542, RHEA:59736] +xref: RHEA:59736 +is_a: GO:0019107 ! myristoyltransferase activity +is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity + +[Term] +id: GO:0019706 +name: protein-cysteine S-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]." [GOC:ai, GOC:pr, RHEA:36683] +synonym: "protein-cysteine S-palmitoleyltransferase activity" RELATED [] +xref: EC:2.3.1.225 +xref: Reactome:R-HSA-5682084 "ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer" +xref: Reactome:R-HSA-9021072 "ZDHHC7, ZDHHC21 palmitoylate ESR1" +xref: RHEA:36683 +is_a: GO:0016409 ! palmitoyltransferase activity +is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity + +[Term] +id: GO:0019707 +name: protein-cysteine S-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule." [GOC:ai] +is_a: GO:0016417 ! S-acyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0019708 +name: peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine +namespace: biological_process +def: "The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins." [RESID:AA0309] +synonym: "peptidyl-glycine cholesteryl ester anabolism from peptidyl-glycine" EXACT [] +synonym: "peptidyl-glycine cholesteryl ester formation from peptidyl-glycine" EXACT [] +synonym: "peptidyl-glycine cholesteryl ester synthesis from peptidyl-glycine" EXACT [] +xref: RESID:AA0309 +is_a: GO:0006501 ! C-terminal protein lipidation +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0008203 ! cholesterol metabolic process +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process + +[Term] +id: GO:0019709 +name: iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide +namespace: biological_process +def: "The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase." [RESID:AA0310] +synonym: "iron incorporation into iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide" EXACT [] +xref: RESID:AA0310 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0019710 +name: peptidyl-asparagine methylation +namespace: biological_process +alt_id: GO:0018018 +def: "The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine." [RESID:AA0070, RESID:AA0311] +xref: RESID:AA0070 +xref: RESID:AA0311 +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0019711 +name: peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid." [GOC:go_curators] +synonym: "peptidyl-beta-carboxyaspartic acid anabolism from peptidyl-aspartic acid" EXACT [] +synonym: "peptidyl-beta-carboxyaspartic acid formation from peptidyl-aspartic acid" EXACT [] +synonym: "peptidyl-beta-carboxyaspartic acid synthesis from peptidyl-aspartic acid" EXACT [] +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0019712 +name: peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid +namespace: biological_process +def: "The methyl esterification of peptidyl-glutamic acid." [RESID:AA0072] +synonym: "peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamic acid" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester formation from glutamic acid" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamic acid" EXACT [] +xref: RESID:AA0072 +is_a: GO:0018390 ! peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine + +[Term] +id: GO:0019713 +name: peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine +namespace: biological_process +def: "The coupled methyl esterification and deamidation of peptidyl-glutamine." [RESID:AA0072] +synonym: "peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamine" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester formation from glutamine" EXACT [] +synonym: "peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamine" EXACT [] +xref: RESID:AA0072 +is_a: GO:0006541 ! glutamine metabolic process +is_a: GO:0018390 ! peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine +is_a: GO:0019714 ! peptidyl-glutamine esterification + +[Term] +id: GO:0019714 +name: peptidyl-glutamine esterification +namespace: biological_process +def: "The addition of an ester group to a glutamine residue in a protein." [GOC:mah] +is_a: GO:0018199 ! peptidyl-glutamine modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0019715 +name: peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid +namespace: biological_process +def: "The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16)." [RESID:AA0027] +comment: See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'. +xref: RESID:AA0027 +is_a: GO:0042264 ! peptidyl-aspartic acid hydroxylation + +[Term] +id: GO:0019716 +name: N-terminal peptidyl-alanine monomethylation +namespace: biological_process +def: "The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine." [RESID:AA0061] +xref: RESID:AA0061 +is_a: GO:0018011 ! N-terminal peptidyl-alanine methylation + +[Term] +id: GO:0019717 +name: obsolete synaptosome +namespace: cellular_component +def: "OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma." [ISBN:0198506732] +comment: This term was made obsolete because it refers to a result of cell homogenization and not a bona fide cellular component. +synonym: "synaptosome" EXACT [] +xref: Wikipedia:Synaptosome +is_obsolete: true +consider: GO:0043005 + +[Term] +id: GO:0019718 +name: obsolete rough microsome +namespace: cellular_component +def: "OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside." [ISBN:0198506732] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "rough microsome" EXACT [] +is_obsolete: true +consider: GO:0005791 + +[Term] +id: GO:0019719 +name: obsolete smooth microsome +namespace: cellular_component +def: "OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes." [ISBN:0198506732] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "smooth microsome" EXACT [] +is_obsolete: true +consider: GO:0005790 + +[Term] +id: GO:0019720 +name: Mo-molybdopterin cofactor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands." [http://www.sunysb.edu/biochem/BIOCHEM/facultypages/schindelin/, ISSN:09498257] +synonym: "Mo-molybdopterin cofactor metabolism" EXACT [] +synonym: "Moco metabolic process" BROAD [] +synonym: "Moco metabolism" BROAD [] +is_a: GO:0043545 ! molybdopterin cofactor metabolic process + +[Term] +id: GO:0019722 +name: calcium-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions." [GOC:signaling] +synonym: "calcium ion signaling" EXACT [] +synonym: "calcium signaling" EXACT [] +synonym: "calcium signalling" EXACT [] +synonym: "calcium-mediated signalling" EXACT [] +xref: Wikipedia:Calcium_signaling +is_a: GO:0019932 ! second-messenger-mediated signaling + +[Term] +id: GO:0019724 +name: B cell mediated immunity +namespace: biological_process +def: "Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "B lymphocyte mediated immune effector process" EXACT [] +synonym: "B lymphocyte mediated immunity" EXACT [] +synonym: "B-cell mediated immune effector process" EXACT [] +synonym: "B-cell mediated immunity" EXACT [] +synonym: "B-lymphocyte mediated immune effector process" EXACT [] +synonym: "B-lymphocyte mediated immunity" EXACT [] +is_a: GO:0002449 ! lymphocyte mediated immunity +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0019725 +name: cellular homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_plant +is_a: GO:0009987 ! cellular process +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0019726 +name: mevaldate reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH." [EC:1.1.1.33, RHEA:20193] +synonym: "(R)-mevalonate:NADP+ oxidoreductase" EXACT [EC:1.1.1.33] +synonym: "mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase" EXACT [EC:1.1.1.33] +xref: EC:1.1.1.33 +xref: KEGG_REACTION:R02247 +xref: MetaCyc:MEVALDATE-REDUCTASE-NADPH-RXN +xref: RHEA:20193 +is_a: GO:0004495 ! mevaldate reductase activity + +[Term] +id: GO:0019727 +name: mevaldate reductase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH." [EC:1.1.1.32, RHEA:13221] +xref: EC:1.1.1.32 +xref: KEGG_REACTION:R02246 +xref: MetaCyc:MEVALDATE-REDUCTASE-RXN +xref: RHEA:13221 +is_a: GO:0004495 ! mevaldate reductase activity + +[Term] +id: GO:0019728 +name: peptidyl-allysine oxidation to 2-aminoadipic acid +namespace: biological_process +def: "The oxidation of allysine to 2-aminoadipic acid." [RESID:AA0122] +xref: RESID:AA0370 +is_a: GO:0018158 ! protein oxidation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0019729 +name: peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine +namespace: biological_process +def: "The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons." [RESID:AA0189] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine" EXACT [] +xref: RESID:AA0189 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018199 ! peptidyl-glutamine modification +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0019730 +name: antimicrobial humoral response +namespace: biological_process +alt_id: GO:0006960 +alt_id: GO:0019735 +def: "An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0006959 ! humoral immune response +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0019731 +name: antibacterial humoral response +namespace: biological_process +alt_id: GO:0006961 +alt_id: GO:0019733 +def: "An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0019730 ! antimicrobial humoral response +is_a: GO:0042742 ! defense response to bacterium + +[Term] +id: GO:0019732 +name: antifungal humoral response +namespace: biological_process +alt_id: GO:0006966 +alt_id: GO:0019734 +def: "An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0019730 ! antimicrobial humoral response +is_a: GO:0050832 ! defense response to fungus + +[Term] +id: GO:0019736 +name: peptidyl-sarcosine incorporation +namespace: biological_process +def: "The incorporation of sarcosine (N-methylglycine) into non-coded peptides." [RESID:AA0063] +xref: RESID:AA0063 +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0019740 +name: nitrogen utilization +namespace: biological_process +def: "A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism." [GOC:mah, GOC:mlg] +is_a: GO:0008150 ! biological_process +relationship: has_part GO:0006807 ! nitrogen compound metabolic process +relationship: has_part GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0019741 +name: pentacyclic triterpenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings." [ISBN:0198506732] +synonym: "pentacyclic triterpenoid breakdown" EXACT [] +synonym: "pentacyclic triterpenoid catabolism" EXACT [] +synonym: "pentacyclic triterpenoid degradation" EXACT [] +is_a: GO:0016105 ! triterpenoid catabolic process +is_a: GO:0019742 ! pentacyclic triterpenoid metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0019742 +name: pentacyclic triterpenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings." [ISBN:0198506732] +synonym: "pentacyclic triterpenoid metabolism" EXACT [] +is_a: GO:0006722 ! triterpenoid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0019743 +name: hopanoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus." [ISBN:0198547684] +synonym: "hopanoid breakdown" EXACT [] +synonym: "hopanoid catabolism" EXACT [] +synonym: "hopanoid degradation" EXACT [] +is_a: GO:0016105 ! triterpenoid catabolic process +is_a: GO:0019744 ! hopanoid metabolic process + +[Term] +id: GO:0019744 +name: hopanoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus." [ISBN:0198547684] +synonym: "hopanoid metabolism" EXACT [] +is_a: GO:0006722 ! triterpenoid metabolic process + +[Term] +id: GO:0019745 +name: pentacyclic triterpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings." [ISBN:0198506732] +synonym: "pentacyclic triterpenoid anabolism" EXACT [] +synonym: "pentacyclic triterpenoid biosynthesis" EXACT [] +synonym: "pentacyclic triterpenoid formation" EXACT [] +synonym: "pentacyclic triterpenoid synthesis" EXACT [] +is_a: GO:0016104 ! triterpenoid biosynthetic process +is_a: GO:0019742 ! pentacyclic triterpenoid metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0019746 +name: hopanoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus." [ISBN:0198547684] +synonym: "hopanoid anabolism" EXACT [] +synonym: "hopanoid biosynthesis" EXACT [] +synonym: "hopanoid formation" EXACT [] +synonym: "hopanoid synthesis" EXACT [] +is_a: GO:0016104 ! triterpenoid biosynthetic process +is_a: GO:0019744 ! hopanoid metabolic process + +[Term] +id: GO:0019747 +name: regulation of isoprenoid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids." [GOC:go_curators] +synonym: "regulation of isoprenoid metabolism" EXACT [] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006720 ! isoprenoid metabolic process +relationship: regulates GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0019748 +name: secondary metabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators] +subset: goslim_aspergillus +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +synonym: "secondary metabolism" EXACT [] +synonym: "secondary metabolite metabolic process" EXACT [] +synonym: "secondary metabolite metabolism" EXACT [] +xref: Wikipedia:Secondary_metabolism +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0019749 +name: cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte +namespace: biological_process +def: "The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte." [GOC:ai] +is_a: GO:0007303 ! cytoplasmic transport, nurse cell to oocyte +is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport +intersection_of: GO:0007303 ! cytoplasmic transport, nurse cell to oocyte +intersection_of: GO:0030705 ! cytoskeleton-dependent intracellular transport + +[Term] +id: GO:0019750 +name: chloroplast localization +namespace: biological_process +def: "Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants." [GOC:bf, GOC:jl, ISBN:0198506732] +synonym: "chloroplast localisation" EXACT [GOC:mah] +is_a: GO:0051644 ! plastid localization + +[Term] +id: GO:0019751 +name: polyol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms." [PMID:30240188] +synonym: "polyhydric alcohol metabolic process" EXACT [] +synonym: "polyol metabolism" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process + +[Term] +id: GO:0019752 +name: carboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] +synonym: "carboxylic acid metabolism" EXACT [] +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0019755 +name: one-carbon compound transport +namespace: biological_process +def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "one carbon compound transport" EXACT [] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0019756 +name: cyanogenic glycoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits." [ISBN:0198506732] +synonym: "cyanogenic glycoside anabolism" EXACT [] +synonym: "cyanogenic glycoside biosynthesis" EXACT [] +synonym: "cyanogenic glycoside formation" EXACT [] +synonym: "cyanogenic glycoside synthesis" EXACT [] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0042341 ! cyanogenic glycoside metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0080028 ! nitrile biosynthetic process + +[Term] +id: GO:0019757 +name: glycosinolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae." [GOC:mah, http://www.gardeneaters.net/family_characteristics.html] +synonym: "glycosinolate metabolism" EXACT [] +is_a: GO:0016143 ! S-glycoside metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0019758 +name: glycosinolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae." [GOC:mah, http://www.gardeneaters.net/family_characteristics.html] +synonym: "glycosinolate anabolism" EXACT [] +synonym: "glycosinolate biosynthesis" EXACT [] +synonym: "glycosinolate formation" EXACT [] +synonym: "glycosinolate synthesis" EXACT [] +is_a: GO:0016144 ! S-glycoside biosynthetic process +is_a: GO:0019757 ! glycosinolate metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0019759 +name: glycosinolate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae." [GOC:mah, http://www.gardeneaters.net/family_characteristics.html] +synonym: "glycosinolate breakdown" EXACT [] +synonym: "glycosinolate catabolism" EXACT [] +synonym: "glycosinolate degradation" EXACT [] +is_a: GO:0016145 ! S-glycoside catabolic process +is_a: GO:0019757 ! glycosinolate metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0019760 +name: glucosinolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans." [GOC:curators] +synonym: "glucosinolate metabolism" EXACT [] +is_a: GO:0019757 ! glycosinolate metabolic process + +[Term] +id: GO:0019761 +name: glucosinolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae." [GOC:ai] +synonym: "glucosinolate anabolism" EXACT [] +synonym: "glucosinolate biosynthesis" EXACT [] +synonym: "glucosinolate formation" EXACT [] +synonym: "glucosinolate synthesis" EXACT [] +is_a: GO:0019758 ! glycosinolate biosynthetic process +is_a: GO:0019760 ! glucosinolate metabolic process + +[Term] +id: GO:0019762 +name: glucosinolate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae." [GOC:ai] +synonym: "glucosinolate breakdown" EXACT [] +synonym: "glucosinolate catabolism" EXACT [] +synonym: "glucosinolate degradation" EXACT [] +xref: MetaCyc:PWY-5267 +is_a: GO:0019759 ! glycosinolate catabolic process +is_a: GO:0019760 ! glucosinolate metabolic process + +[Term] +id: GO:0019763 +name: immunoglobulin receptor activity +namespace: molecular_function +alt_id: GO:0016489 +def: "Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:signaling, ISBN:0198547684] +synonym: "FC receptor activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0019865 ! immunoglobulin binding +relationship: part_of GO:0038093 ! Fc receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0019764 +name: obsolete high affinity Fc receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:add] +comment: This term was made obsolete because it is an unnecessary grouping term. +synonym: "high affinity Fc receptor activity" EXACT [] +is_obsolete: true +consider: GO:0019768 +consider: GO:0019771 + +[Term] +id: GO:0019765 +name: obsolete low affinity Fc receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:add] +comment: This term was made obsolete because it is undefined and is an unnecessary grouping term. +synonym: "low affinity Fc receptor activity" EXACT [] +is_obsolete: true +consider: GO:0019769 +consider: GO:0019772 + +[Term] +id: GO:0019766 +name: IgA receptor activity +namespace: molecular_function +def: "Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0019763 ! immunoglobulin receptor activity +relationship: has_part GO:0019862 ! IgA binding + +[Term] +id: GO:0019767 +name: IgE receptor activity +namespace: molecular_function +def: "Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0019763 ! immunoglobulin receptor activity +relationship: has_part GO:0019863 ! IgE binding +relationship: part_of GO:0038095 ! Fc-epsilon receptor signaling pathway + +[Term] +id: GO:0019768 +name: high-affinity IgE receptor activity +namespace: molecular_function +def: "Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +synonym: "high affinity Fc receptor activity" RELATED [] +synonym: "high affinity IgE receptor activity" EXACT [] +is_a: GO:0019767 ! IgE receptor activity + +[Term] +id: GO:0019769 +name: low-affinity IgE receptor activity +namespace: molecular_function +def: "Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +synonym: "low affinity Fc receptor activity" RELATED [] +synonym: "low affinity IgE receptor activity" EXACT [] +is_a: GO:0019767 ! IgE receptor activity + +[Term] +id: GO:0019770 +name: IgG receptor activity +namespace: molecular_function +def: "Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +is_a: GO:0019763 ! immunoglobulin receptor activity +relationship: has_part GO:0019864 ! IgG binding +relationship: part_of GO:0038094 ! Fc-gamma receptor signaling pathway + +[Term] +id: GO:0019771 +name: high-affinity IgG receptor activity +namespace: molecular_function +def: "Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +synonym: "high affinity Fc receptor activity" RELATED [] +synonym: "high affinity IgG receptor activity" EXACT [] +is_a: GO:0019770 ! IgG receptor activity + +[Term] +id: GO:0019772 +name: low-affinity IgG receptor activity +namespace: molecular_function +def: "Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +synonym: "low affinity Fc receptor activity" RELATED [] +synonym: "low affinity IgG receptor activity" EXACT [] +is_a: GO:0019770 ! IgG receptor activity + +[Term] +id: GO:0019773 +name: proteasome core complex, alpha-subunit complex +namespace: cellular_component +def: "The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus." [GOC:jl, GOC:mtg_sensu, GOC:rb, PMID:10854779] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005839 ! proteasome core complex + +[Term] +id: GO:0019774 +name: proteasome core complex, beta-subunit complex +namespace: cellular_component +def: "The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus." [GOC:jl, GOC:mtg_sensu, GOC:rb, PMID:10854779] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005839 ! proteasome core complex + +[Term] +id: GO:0019775 +name: FAT10 transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages." [GOC:dph, GOC:mah, PMID:12826404] +synonym: "FAT10 conjugating enzyme activity" NARROW [] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity + +[Term] +id: GO:0019776 +name: Atg8 ligase activity +namespace: molecular_function +def: "Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate." [GOC:mah, PMID:12826404] +synonym: "APG8 conjugating enzyme activity" EXACT [] +synonym: "APG8 ligase activity" EXACT [] +synonym: "Atg8 conjugating enzyme activity" EXACT [] +xref: Reactome:R-HSA-5681981 "ATG3 transfers LC3 from ATG7 to ATG3" +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0019777 +name: Atg12 transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages." [GOC:mah, PMID:12826404] +synonym: "APG12 conjugating enzyme activity" NARROW [] +synonym: "APG12 ligase activity" NARROW [] +synonym: "Atg12 conjugating enzyme activity" NARROW [] +synonym: "Atg12 ligase activity" NARROW [] +xref: Reactome:R-HSA-5681999 "ATG10 transfers ATG12 from ATG7 to ATG10" +is_a: GO:0019787 ! ubiquitin-like protein transferase activity + +[Term] +id: GO:0019778 +name: Atg12 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +synonym: "APG12 activating enzyme activity" RELATED [GOC:vw] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019779 +name: Atg8 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +synonym: "APG7" EXACT [] +synonym: "APG8 activating enzyme activity" RELATED [GOC:vw] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019780 +name: FAT10 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019781 +name: NEDD8 activating enzyme activity +namespace: molecular_function +alt_id: GO:0019944 +def: "Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade." [PMID:12646924] +synonym: "RUB1 activating enzyme activity" EXACT [] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019782 +name: ISG15 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +synonym: "UBE1L" NARROW [] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019783 +name: ubiquitin-like protein-specific protease activity +namespace: molecular_function +alt_id: GO:1904454 +alt_id: GO:1904455 +def: "Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated." [GOC:ma, GOC:mah] +synonym: "small conjugating protein-specific protease activity" EXACT [GOC:dph] +synonym: "ubiquitin-like specific protease activity" NARROW [] +synonym: "ubiquitin-like-protein-specific protease activity" NARROW [] +synonym: "ubiquitin-specific protease activity involved in negative regulation of ERAD pathway" NARROW [] +synonym: "ubiquitin-specific protease activity involved in positive regulation of ERAD pathway" NARROW [] +is_a: GO:0008234 ! cysteine-type peptidase activity + +[Term] +id: GO:0019784 +name: NEDD8-specific protease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates." [GOC:mah] +synonym: "deneddylase activity" EXACT [GOC:dph] +xref: Reactome:R-HSA-5690808 "UCHL3, SENP8 cleave NEDD8" +xref: Reactome:R-HSA-8863723 "COP9 and TOR1 deneddylate STON2" +xref: Reactome:R-HSA-8956040 "COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes" +xref: Reactome:R-HSA-8956045 "COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex" +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity + +[Term] +id: GO:0019785 +name: ISG15-specific protease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates." [GOC:mah] +xref: Reactome:R-HSA-1678841 "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18" +xref: Reactome:R-HSA-5653786 "USP43 deISGylates ISG:K164,ISG:K168-PCNA" +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity + +[Term] +id: GO:0019786 +name: Atg8-specific protease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier." [GOC:mah] +synonym: "APG8-PE hydrolase" RELATED [] +synonym: "APG8-specific protease activity" RELATED [GOC:vw] +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity + +[Term] +id: GO:0019787 +name: ubiquitin-like protein transferase activity +namespace: molecular_function +alt_id: GO:0008639 +alt_id: GO:0008640 +def: "Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein." [GOC:mah, GOC:rn, PMID:10806345, PMID:10884686] +subset: goslim_drosophila +subset: goslim_pir +synonym: "E2" RELATED [] +synonym: "E3" RELATED [dph:GOC] +synonym: "small conjugating protein ligase activity" NARROW [GOC:dph] +synonym: "small conjugating protein transferase activity" EXACT [GOC:dph] +synonym: "small protein conjugating enzyme activity" NARROW [] +synonym: "ubiquitin-like conjugating enzyme activity" NARROW [] +synonym: "ubiquitin-like-protein ligase activity" NARROW [] +xref: Reactome:R-HSA-5678490 "ATG16L1 complex transfers LC3 from ATG3 to PE" +xref: Reactome:R-HSA-688137 "RIP2 is K63 polyubiquitinated" +is_a: GO:0016740 ! transferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0019788 +name: NEDD8 transferase activity +namespace: molecular_function +alt_id: GO:0016976 +alt_id: GO:0019945 +alt_id: GO:0042295 +def: "Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages." [GOC:mah] +synonym: "Hub1 conjugating enzyme activity" RELATED [] +synonym: "NEDD8 conjugating enzyme activity" RELATED [] +synonym: "RUB1 conjugating enzyme activity" RELATED [] +xref: Reactome:R-HSA-8951648 "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1" +xref: Reactome:R-HSA-8951661 "Transfer of NEDD8 to AcM-UBE2M" +xref: Reactome:R-HSA-8951764 "Transfer of NEDD8 to AcM-UBE2F" +xref: Reactome:R-HSA-8952044 "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex" +xref: Reactome:R-HSA-8952618 "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex" +xref: Reactome:R-HSA-8952638 "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex" +xref: Reactome:R-HSA-8956025 "AcM-UBE2M transfers NEDD8 to CUL9:RBX1" +is_a: GO:0019787 ! ubiquitin-like protein transferase activity + +[Term] +id: GO:0019789 +name: SUMO transferase activity +namespace: molecular_function +alt_id: GO:0016930 +alt_id: GO:0019949 +def: "Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages." [GOC:rn, PMID:11031248, PMID:11265250] +synonym: "SMT3 conjugating enzyme" RELATED [] +synonym: "SUMO conjugating enzyme activity" RELATED [] +xref: Reactome:R-HSA-2993769 "Transfer of SUMO3 from E1 to UBE2I (UBC9)" +xref: Reactome:R-HSA-2993780 "Transfer of SUMO1 from E1 to UBE2I (UBC9)" +xref: Reactome:R-HSA-2993790 "Transfer of SUMO2 from E1 to UBE2I (UBC9)" +xref: Reactome:R-HSA-2997616 "PIAS1,4 SUMOylates BRCA1 with SUMO2,3" +xref: Reactome:R-HSA-2997706 "MDM2 SUMOylates TP53 with SUMO2,3" +xref: Reactome:R-HSA-2997709 "PIAS1,4 SUMOylates BRCA1 with SUMO1" +xref: Reactome:R-HSA-2997723 "PIAS4 SUMOylates TP53BP1 with SUMO1" +xref: Reactome:R-HSA-3000348 "RANBP2 SUMOylates SP100 with SUMO2" +xref: Reactome:R-HSA-3000383 "UBE2I, HDAC7 SUMOylate PML with SUMO1" +xref: Reactome:R-HSA-3000399 "RANBP2 SUMOylates SP100 with SUMO1" +xref: Reactome:R-HSA-3000411 "RANBP2 SUMOylates PML with SUMO2" +xref: Reactome:R-HSA-3000433 "SUMOylation of PML with SUMO3" +xref: Reactome:R-HSA-3000434 "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1" +xref: Reactome:R-HSA-3108203 "PRC1 SUMOylates CTBP1 with SUMO2,3" +xref: Reactome:R-HSA-3108209 "PRC1 SUMOylates CTBP1 with SUMO1" +xref: Reactome:R-HSA-3108212 "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1" +xref: Reactome:R-HSA-3232162 "PIAS3 SUMOylates MITF with SUMO1" +xref: Reactome:R-HSA-3234081 "SUMOylation of TFAP2A with SUMO1" +xref: Reactome:R-HSA-3234084 "SUMOylation of TFAP2B with SUMO1" +xref: Reactome:R-HSA-3234094 "SUMOylation of TFAP2C with SUMO1" +xref: Reactome:R-HSA-3247493 "PIAS1 SUMOylates SP3 with SUMO1" +xref: Reactome:R-HSA-3296126 "CBX4, UHRF2 SUMOylate ZNF131 with SUMO1" +xref: Reactome:R-HSA-3465545 "PIAS1,3,4 SUMOylate MTA1 with SUMO2,3" +xref: Reactome:R-HSA-3782535 "TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1" +xref: Reactome:R-HSA-3899291 "SUMOylation of EP300 with SUMO1" +xref: Reactome:R-HSA-3900047 "SUMOylation of DDX17 with SUMO1" +xref: Reactome:R-HSA-3900070 "SUMOylation of MKL1 with SUMO1" +xref: Reactome:R-HSA-3900177 "SUMOylation of DDX5 with SUMO1" +xref: Reactome:R-HSA-3900194 "PIAS1 SUMOylates DDX5 with SUMO2" +xref: Reactome:R-HSA-3903017 "SUMOylation of PPARGC1A with SUMO1" +xref: Reactome:R-HSA-3927824 "PRC1 SUMOylates CASP8AP2 with SUMO1" +xref: Reactome:R-HSA-3927886 "SUMOylation of NCOR2 with SUMO1" +xref: Reactome:R-HSA-3927959 "SUMOylation of CREBBP with SUMO1" +xref: Reactome:R-HSA-3968362 "SUMOylation of PIAS4 with SUMO1" +xref: Reactome:R-HSA-3968414 "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1" +xref: Reactome:R-HSA-4085296 "SUMOylation of NCOA1 with SUMO1" +xref: Reactome:R-HSA-4085318 "SUMOylation of NCOA2 with SUMO1" +xref: Reactome:R-HSA-4085331 "PIAS2-1 SUMOylates PARK7 with SUMO1" +xref: Reactome:R-HSA-4085347 "PIAS1 SUMOylates SAFB with SUMO1" +xref: Reactome:R-HSA-4085350 "SUMOylation of UBE2I with SUMO1" +xref: Reactome:R-HSA-4085372 "PIAS1 SUMOylates SAFB with SUMO2,3" +xref: Reactome:R-HSA-4085992 "SUMOylation of DAXX with SUMO1" +xref: Reactome:R-HSA-4085994 "TOPORS SUMOylates SIN3A with SUMO1" +xref: Reactome:R-HSA-4086036 "PIAS1,3 SUMOylate NRIP1 with SUMO1" +xref: Reactome:R-HSA-4086059 "SUMOylation of NPM1 with SUMO2,3" +xref: Reactome:R-HSA-4086083 "SUMOylation of ING2 with SUMO1" +xref: Reactome:R-HSA-4086088 "SUMOylation of NPM1 with SUMO1" +xref: Reactome:R-HSA-4090281 "PIAS1,2-1 SUMOylate HIC1 with SUMO1" +xref: Reactome:R-HSA-4090284 "SUMOylation of HIPK2 with SUMO1" +xref: Reactome:R-HSA-4090288 "PIAS1,3 SUMOylate MBD1 with SUMO1" +xref: Reactome:R-HSA-4090390 "PIAS1,2-1 SUMOylates AR with SUMO1" +xref: Reactome:R-HSA-4090408 "PIAS1,3 SUMOylate ESR1 with SUMO1" +xref: Reactome:R-HSA-4341016 "PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1" +xref: Reactome:R-HSA-4341025 "SUMOylation of NR3C1 (GR) with SUMO1" +xref: Reactome:R-HSA-4341048 "SUMOylation of RXRA with SUMO1" +xref: Reactome:R-HSA-4341070 "PIAS4 SUMOylates PPARA with SUMO1" +xref: Reactome:R-HSA-4341072 "SUMOylation of RARA with SUMO2" +xref: Reactome:R-HSA-4341073 "PIAS3 SUMOylates PGR with SUMO1" +xref: Reactome:R-HSA-4546385 "PIAS1,3 SUMOylates NR5A1 with SUMO2" +xref: Reactome:R-HSA-4546386 "PIAS1,3 SUMOylates NR5A1 with SUMO1" +xref: Reactome:R-HSA-4546387 "PIAS4 SUMOylates VDR with SUMO2" +xref: Reactome:R-HSA-4551604 "PIAS4 SUMOylates PARP1 with SUMO1" +xref: Reactome:R-HSA-4551616 "SUMOylation of RPA1 (RPA70) with SUMO2,3" +xref: Reactome:R-HSA-4551648 "SUMOylation of TDG with SUMO1" +xref: Reactome:R-HSA-4551649 "RANBP2 SUMOylates RANBP2 with SUMO1" +xref: Reactome:R-HSA-4551655 "CBX4 SUMOylates BMI1 in PRC1 with SUMO1" +xref: Reactome:R-HSA-4551661 "PIAS4 SUMOylates RNF168 with SUMO1" +xref: Reactome:R-HSA-4551679 "RANBP2 SUMOylates RANBP2 with SUMO2" +xref: Reactome:R-HSA-4551683 "SUMOylation of TOPORS with SUMO1" +xref: Reactome:R-HSA-4551721 "PIAS4 SUMOylates VHL with SUMO1" +xref: Reactome:R-HSA-4551724 "PIAS4 SUMOylates HERC2 with SUMO1" +xref: Reactome:R-HSA-4551727 "CBX4 SUMOylates CBX4 in PRC1 with SUMO1" +xref: Reactome:R-HSA-4551738 "SUMOylation of TDG with SUMO2,3" +xref: Reactome:R-HSA-4551768 "PIAS4 SUMOylates PARP1 with SUMO2,3" +xref: Reactome:R-HSA-4568846 "CDKN2A (p14-ARF) SUMOylates WRN with SUMO1" +xref: Reactome:R-HSA-4568848 "PIAS1,2-1 SUMOylates XRCC4 with SUMO1" +xref: Reactome:R-HSA-4568863 "SUMOylation of RAD52 with SUMO1" +xref: Reactome:R-HSA-4568914 "SUMOylation of BLM with SUMO2,3" +xref: Reactome:R-HSA-4570463 "CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3" +xref: Reactome:R-HSA-4570467 "SUMOylation of NOP58 with SUMO1" +xref: Reactome:R-HSA-4570485 "SUMOylation of Histone H4 with SUMO3" +xref: Reactome:R-HSA-4570489 "SUMOylation of NOP58 with SUMO2" +xref: Reactome:R-HSA-4570493 "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1" +xref: Reactome:R-HSA-4570496 "SUMOylation of Histone H4 with SUMO1" +xref: Reactome:R-HSA-4570499 "CBX4 (Pc2) SUMOylates HNRNPK with SUMO2" +xref: Reactome:R-HSA-4570528 "SUMOylation of XPC with SUMO1" +xref: Reactome:R-HSA-4570553 "SUMOylation of MDC1 with SUMO2,3" +xref: Reactome:R-HSA-4570554 "SUMOylation of MDC1 with SUMO1" +xref: Reactome:R-HSA-4615839 "PIAS1 SUMOylates SATB1 with SUMO2,3" +xref: Reactome:R-HSA-4615872 "RANBP2 SUMOylates HDAC4 with SUMO1" +xref: Reactome:R-HSA-4615873 "PIAS2-2 SUMOylates SUZ12 with SUMO1" +xref: Reactome:R-HSA-4615889 "SUMOylation of HDAC1 with SUMO1" +xref: Reactome:R-HSA-4615900 "PIAS1 SUMOylates SATB2 with SUMO3" +xref: Reactome:R-HSA-4615905 "PIAS1 SUMOylates SATB1 with SUMO1" +xref: Reactome:R-HSA-4615910 "SUMOylation of PCNA with SUMO1" +xref: Reactome:R-HSA-4615933 "SUMOylation of CBX5 with SUMO1" +xref: Reactome:R-HSA-4615987 "RANBP2 SUMOylates HDAC4 with SUMO2,3" +xref: Reactome:R-HSA-4616015 "SUMOylation of HDAC2 with SUMO1" +xref: Reactome:R-HSA-4641342 "SUMOylation of TOP2A with SUMO1" +xref: Reactome:R-HSA-4641345 "SUMOylation of TOP2B with SUMO1" +xref: Reactome:R-HSA-4641350 "PIAS4 SUMOylates TOP2A with SUMO2,3" +xref: Reactome:R-HSA-4641362 "SUMOylation of TOP1 with SUMO1" +xref: Reactome:R-HSA-4655355 "RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B)" +xref: Reactome:R-HSA-4655374 "SUMOylation of DNMT3B with SUMO1" +xref: Reactome:R-HSA-4655431 "SUMOyation of DNMT1 with SUMO1" +xref: Reactome:R-HSA-4655440 "CBX4 (Pc2) SUMOylates DNMT3A with SUMO1" +xref: Reactome:R-HSA-4656914 "SUMOylation of NFKBIA with SUMO1" +xref: Reactome:R-HSA-4717461 "PIAS1,2-2 SUMOylate PPARG with SUMO1" +xref: Reactome:R-HSA-4717521 "PIAS1 SUMOylates NR2C1 (TR2)" +xref: Reactome:R-HSA-4719413 "PIAS2,3,4 SUMOylate RORA with SUMO2" +xref: Reactome:R-HSA-4719423 "PIAS2-2 SUMOylates THRA with SUMO3" +xref: Reactome:R-HSA-4719424 "PIAS1 SUMOylates THRB with SUMO1." +xref: Reactome:R-HSA-4719436 "PIAS2,3,4 SUMOylate RORA with SUMO1" +xref: Reactome:R-HSA-4719447 "PIAS2-2 SUMOylates THRA with SUMO1" +xref: Reactome:R-HSA-4719448 "PIAS1 SUMOylates THRB with SUMO3" +xref: Reactome:R-HSA-4720432 "HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3" +xref: Reactome:R-HSA-4720446 "HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3" +xref: Reactome:R-HSA-4755411 "PIAS4 SUMOylates IKBKG with SUMO1" +xref: Reactome:R-HSA-4755478 "TOPORS SUMOylates IKBKE with SUMO1" +xref: Reactome:R-HSA-4755479 "SUMOylation of NFKB2 with SUMO1" +xref: Reactome:R-HSA-4755494 "PIAS1,2-1 SUMOylate NR5A2 with SUMO1" +xref: Reactome:R-HSA-4755526 "PIAS4 SUMOylates NR4A2 with SUMO2,3" +xref: Reactome:R-HSA-4755536 "PIAS3 SUMOylates RELA with SUMO3" +xref: Reactome:R-HSA-5228508 "RANBP2 SUMOylates PML with SUMO1" +xref: Reactome:R-HSA-5228521 "PIAS1,4 SUMOylate CASP8AP2 with SUMO1" +xref: Reactome:R-HSA-5228523 "RANBP2 SUMOylates MDM2 with SUMO1" +xref: Reactome:R-HSA-5228525 "RANBP2 SUMOylates TOP2A with SUMO1" +xref: Reactome:R-HSA-5682607 "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs" +xref: Reactome:R-HSA-5684052 "PIAS4 SUMOylates MDC1" +xref: Reactome:R-HSA-6790454 "SUMOylation of XPC" +xref: Reactome:R-HSA-6804468 "PIAS1 SUMOylates SP3 with SUMO2" +xref: Reactome:R-HSA-6804485 "PIAS1 SUMOylates L3MBTL2 with SUMO2" +xref: Reactome:R-HSA-8956365 "ZBED1 (DREF) SUMOylates CHD3 with SUMO1" +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +relationship: part_of GO:0016925 ! protein sumoylation + +[Term] +id: GO:0019790 +name: obsolete ubiquitin-like hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. +synonym: "ubiquitin-like hydrolase activity" EXACT [] +is_obsolete: true +consider: GO:0019783 + +[Term] +id: GO:0019791 +name: obsolete FAT10 hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. +synonym: "FAT10 hydrolase activity" EXACT [] +is_obsolete: true +consider: GO:0019783 + +[Term] +id: GO:0019792 +name: obsolete APG12 hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. +synonym: "APG12 hydrolase activity" EXACT [] +is_obsolete: true +consider: GO:0019783 + +[Term] +id: GO:0019793 +name: obsolete ISG15 carrier activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other." [GOC:jl, http://www.copewithcytokines.de/] +comment: This term was made obsolete because it is gene product-specific. +synonym: "interferon-stimulated gene-15 carrier activity" NARROW [] +synonym: "ISG15 carrier activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0019794 +name: obsolete nonprotein amino acid metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity. +synonym: "nonprotein amino acid metabolic process" EXACT [] +synonym: "nonprotein amino acid metabolism" EXACT [] +is_obsolete: true +replaced_by: GO:0006520 + +[Term] +id: GO:0019795 +name: obsolete nonprotein amino acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins." [GOC:ma] +comment: This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity. +synonym: "nonprotein amino acid anabolism" EXACT [] +synonym: "nonprotein amino acid biosynthesis" EXACT [] +synonym: "nonprotein amino acid biosynthetic process" EXACT [] +synonym: "nonprotein amino acid formation" EXACT [] +synonym: "nonprotein amino acid synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0008652 + +[Term] +id: GO:0019796 +name: obsolete nonprotein amino acid catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity. +synonym: "nonprotein amino acid breakdown" EXACT [] +synonym: "nonprotein amino acid catabolic process" EXACT [] +synonym: "nonprotein amino acid catabolism" EXACT [] +synonym: "nonprotein amino acid degradation" EXACT [] +is_obsolete: true +replaced_by: GO:0009063 + +[Term] +id: GO:0019797 +name: procollagen-proline 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.7] +synonym: "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.7] +synonym: "procollagen-proline,2-oxoglutarate 3-dioxygenase activity" EXACT [EC:1.14.11.7] +synonym: "proline,2-oxoglutarate 3-dioxygenase activity" EXACT [EC:1.14.11.7] +synonym: "prolyl 3-hydroxylase activity" BROAD [EC:1.14.11.7] +synonym: "prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity" EXACT [EC:1.14.11.7] +synonym: "protocollagen proline 3-hydroxylase activity" EXACT [EC:1.14.11.7] +xref: EC:1.14.11.7 +xref: KEGG_REACTION:R03218 +xref: MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN +xref: Reactome:R-HSA-1980233 "Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen" +is_a: GO:0019798 ! procollagen-proline dioxygenase activity +is_a: GO:0031544 ! peptidyl-proline 3-dioxygenase activity + +[Term] +id: GO:0019798 +name: procollagen-proline dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.2, EC:1.14.11.7, GOC:mah] +is_a: GO:0031543 ! peptidyl-proline dioxygenase activity + +[Term] +id: GO:0019799 +name: tubulin N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine." [EC:2.3.1.108] +synonym: "acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity" EXACT [EC:2.3.1.108] +synonym: "acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.108] +synonym: "acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity" EXACT [EC:2.3.1.108] +synonym: "alpha-tubulin acetylase activity" EXACT [EC:2.3.1.108] +synonym: "alpha-tubulin acetyltransferase activity" EXACT [EC:2.3.1.108] +synonym: "alpha-tubulin N-acetyltransferase activity" EXACT [EC:2.3.1.108] +synonym: "TAT activity" EXACT [EC:2.3.1.108] +synonym: "tubulin acetyltransferase activity" EXACT [EC:2.3.1.108] +xref: EC:2.3.1.108 +xref: MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN +is_a: GO:0061733 ! peptide-lysine-N-acetyltransferase activity + +[Term] +id: GO:0019800 +name: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan +namespace: biological_process +def: "The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain." [PMID:1898736, RESID:AA0219] +synonym: "peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan" EXACT [] +xref: RESID:AA0219 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0030204 ! chondroitin sulfate metabolic process + +[Term] +id: GO:0019801 +name: cyclization of asparagine involved in intein-mediated protein splicing +namespace: biological_process +def: "The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing." [RESID:AA0302] +comment: See also the biological process term 'intein-mediated protein splicing ; GO:0016539'. +synonym: "cyclization of asparagine, during protein splicing" RELATED [GOC:dph, GOC:tb] +xref: RESID:AA0302 +is_a: GO:0006528 ! asparagine metabolic process +relationship: part_of GO:0016539 ! intein-mediated protein splicing + +[Term] +id: GO:0019802 +name: cyclization of glutamine involved in intein-mediated protein splicing +namespace: biological_process +def: "The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing." [GOC:dph, GOC:tb, RESID:AA0303] +comment: Note that this term should not be confused with 'peptidyl-pyroglutamic acid biosynthesis, using glutaminyl-peptide cyclotransferase ; GO:0017186'. See also the biological process term 'intein-mediated protein splicing ; GO:0016539'. +synonym: "cyclization of glutamine, during protein splicing" RELATED [GOC:dph, GOC:tb] +xref: RESID:AA0303 +is_a: GO:0006541 ! glutamine metabolic process +relationship: part_of GO:0016539 ! intein-mediated protein splicing + +[Term] +id: GO:0019803 +name: peptidyl-aspartic acid carboxylation +namespace: biological_process +def: "The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid." [RESID:AA0304] +xref: RESID:AA0304 +is_a: GO:0018197 ! peptidyl-aspartic acid modification +is_a: GO:0018214 ! protein carboxylation + +[Term] +id: GO:0019804 +name: obsolete quinolinate synthetase complex +namespace: cellular_component +def: "OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate." [UniProtKB:P10902] +comment: This term was made obsolete because there is no evidence that a physical complex forms; although the phrase "quinolinate synthetase complex" is occasionally used in the literature, it refers to two enzymes that act as monomers. +synonym: "quinolinate synthetase complex" EXACT [] +is_obsolete: true +consider: GO:0008743 +consider: GO:0008987 + +[Term] +id: GO:0019805 +name: quinolinate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid." [GOC:ai] +synonym: "quinolinate anabolism" EXACT [] +synonym: "quinolinate biosynthesis" EXACT [] +synonym: "quinolinate formation" EXACT [] +synonym: "quinolinate synthesis" EXACT [] +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046874 ! quinolinate metabolic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process + +[Term] +id: GO:0019806 +name: bromide peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide." [EC:1.11.1.18] +synonym: "bromoperoxidase activity" EXACT [] +xref: EC:1.11.1.18 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0019807 +name: aspartoacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate." [EC:3.5.1.15] +synonym: "acetyl-aspartic deaminase activity" EXACT [EC:3.5.1.15] +synonym: "acylase II" RELATED [EC:3.5.1.15] +synonym: "aminoacylase II activity" RELATED [EC:3.5.1.15] +synonym: "N-acetylaspartate amidohydrolase activity" EXACT [EC:3.5.1.15] +synonym: "N-acyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.15] +xref: EC:3.5.1.15 +xref: MetaCyc:ASPARTOACYLASE-RXN +xref: Reactome:R-HSA-5691507 "ASPA deacetylates NAA to acetate and L-aspartate" +xref: RHEA:10872 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0019808 +name: polyamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with polyamines, organic compounds containing two or more amino groups." [GOC:ai] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0019809 +name: spermidine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] +is_a: GO:0019808 ! polyamine binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0019810 +name: putrescine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine." [GOC:ai] +is_a: GO:0019808 ! polyamine binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0019811 +name: cocaine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis." [GOC:jl, ISBN:0198506732] +is_a: GO:0008144 ! drug binding +is_a: GO:0043169 ! cation binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0019812 +name: type I site-specific deoxyribonuclease complex +namespace: cellular_component +def: "A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995, PMID:15788748] +synonym: "type I restriction enzyme complex" EXACT [] +is_a: GO:1905347 ! endodeoxyribonuclease complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0019813 +name: type III site-specific deoxyribonuclease complex +namespace: cellular_component +def: "A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995] +synonym: "type III restriction enzyme complex" EXACT [] +is_a: GO:1905347 ! endodeoxyribonuclease complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0019814 +name: immunoglobulin complex +namespace: cellular_component +def: "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, GOC:jl, ISBN:0781765196] +comment: Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +subset: goslim_pir +synonym: "antibody" NARROW [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0019815 +name: B cell receptor complex +namespace: cellular_component +alt_id: GO:0042570 +def: "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781735149] +comment: Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "antibody" RELATED [GOC:mah] +synonym: "B cell receptor accessory molecule complex" RELATED [] +synonym: "B lymphocyte receptor complex" EXACT [] +synonym: "B-cell receptor complex" EXACT [] +synonym: "B-lymphocyte receptor complex" EXACT [] +synonym: "BCR complex" EXACT [] +synonym: "immunoglobulin complex, membrane bound" EXACT [] +is_a: GO:0019814 ! immunoglobulin complex +is_a: GO:0098802 ! plasma membrane signaling receptor complex + +[Term] +id: GO:0019816 +name: obsolete B cell receptor accessory molecule complex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it represents a molecule and not a location or complex. +synonym: "B cell receptor accessory molecule complex" EXACT [] +is_obsolete: true +consider: GO:0019815 + +[Term] +id: GO:0019817 +name: vesicle fusion with peroxisome +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome." [GOC:jid] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0007031 ! peroxisome organization + +[Term] +id: GO:0019819 +name: P1 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019820 +name: P2 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019821 +name: P3 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019822 +name: P4 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019823 +name: P5 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P6 peroxisome ; GO:0019824'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019824 +name: P6 peroxisome +namespace: cellular_component +def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes." [PMID:10629216] +comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P5 peroxisome ; GO:0019823'. +synonym: "peroxisome vesicle" BROAD [] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0019825 +name: oxygen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oxygen (O2)." [GOC:jl] +subset: goslim_pir +subset: goslim_plant +synonym: "cytochrome P450" NARROW [] +synonym: "cytochrome P450 activity" RELATED [] +is_a: GO:0008144 ! drug binding +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0019826 +name: oxygen sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2)." [GOC:mah] +is_a: GO:0019825 ! oxygen binding +is_a: GO:0140299 ! small molecule sensor activity + +[Term] +id: GO:0019827 +name: stem cell population maintenance +namespace: biological_process +def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] +synonym: "maintenance of pluripotency" RELATED [GOC:vk] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0098727 ! maintenance of cell number + +[Term] +id: GO:0019828 +name: aspartic-type endopeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process." [GOC:ai] +synonym: "aspartic protease inhibitor activity" NARROW [] +is_a: GO:0004866 ! endopeptidase inhibitor activity +relationship: negatively_regulates GO:0004190 ! aspartic-type endopeptidase activity + +[Term] +id: GO:0019829 +name: ATPase-coupled cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)." [GOC:ai] +synonym: "ATP-dependent cation transmembrane transporter activity" EXACT [] +synonym: "cation ABC transporter" NARROW [] +synonym: "cation-transporting ATPase activity" EXACT [] +synonym: "plasma membrane cation-transporting ATPase" NARROW [] +xref: Reactome:R-HSA-5251989 "ATP13A4,5 transport divalent ions from extracellular region to cytosol" +xref: Reactome:R-HSA-5692480 "ATP13A2 transports cations from cytosol to lysosomal lumen" +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0019830 +name: obsolete cadmium sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "cadmium sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046686 + +[Term] +id: GO:0019831 +name: obsolete chromate sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "chromate sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046687 + +[Term] +id: GO:0019832 +name: obsolete mercuric sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "mercuric sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046689 + +[Term] +id: GO:0019833 +name: obsolete ice nucleation activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation." [GOC:ai, GOC:jl] +comment: This term was made obsolete because it represents a biological process. +synonym: "ice nucleation activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0042309 +consider: GO:0050825 + +[Term] +id: GO:0019834 +name: phospholipase A2 inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of the enzyme phospholipase A2." [GOC:ai] +is_a: GO:0004859 ! phospholipase inhibitor activity +relationship: negatively_regulates GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0019835 +name: cytolysis +namespace: biological_process +def: "The rupture of cell membranes and the loss of cytoplasm." [UniProtKB-KW:KW-0204] +subset: goslim_chembl +synonym: "autolysin activity" RELATED [] +synonym: "bacteriocin activity" RELATED [] +synonym: "bacteriolytic toxin activity" RELATED [] +synonym: "holin" RELATED [] +synonym: "lysin activity" RELATED [] +synonym: "lysis" BROAD [] +synonym: "necrosis" RELATED [] +xref: Wikipedia:Cytolysis +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0019836 +name: hemolysis by symbiont of host erythrocytes +namespace: biological_process +def: "The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add, UniProtKB-KW:KW-0354] +synonym: "haemolysis in host" EXACT [] +synonym: "hemolysin activity" RELATED [] +synonym: "hemolysis by symbiont of host RBCs" EXACT [CL:0000232] +synonym: "hemolysis by symbiont of host red blood cells" EXACT [CL:0000232] +synonym: "regulation of cytolysis of host cells by symbiont" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001897 ! cytolysis by symbiont of host cells +is_a: GO:0052331 ! hemolysis in other organism involved in symbiotic interaction + +[Term] +id: GO:0019837 +name: obsolete herbicide susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "herbicide susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0009635 + +[Term] +id: GO:0019838 +name: growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate." [GOC:curators] +subset: goslim_chembl +synonym: "neurotrophin TRK receptor activity" RELATED [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon_Union:0000023 + +[Term] +id: GO:0019840 +name: isoprenoid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [GOC:jl] +subset: goslim_pir +is_a: GO:0008289 ! lipid binding + +[Term] +id: GO:0019841 +name: retinol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation." [GOC:curators] +synonym: "vitamin A1 alcohol binding" EXACT [] +synonym: "vitamin A1 binding" EXACT [] +is_a: GO:0005501 ! retinoid binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0019842 +name: vitamin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] +subset: goslim_metagenomics +subset: goslim_pir +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0019843 +name: rRNA binding +namespace: molecular_function +alt_id: GO:0000944 +def: "Interacting selectively and non-covalently with ribosomal RNA." [GOC:jl] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "base pairing with rRNA" NARROW [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0019844 +name: obsolete endotoxin activity +namespace: molecular_function +def: "OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell." [ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "endotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0005622 +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0019845 +name: obsolete exotoxin activity +namespace: molecular_function +def: "OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium." [ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "exotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0005576 +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0019846 +name: obsolete enterotoxin activity +namespace: molecular_function +def: "OBSOLETE. Acts as to cause injury to the intestinal mucosa of other living organisms." [ISBN:0198506732] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "enterotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0019847 +name: obsolete neurotoxin activity +namespace: molecular_function +def: "OBSOLETE. Acts to inhibit neural function in another living organism." [GOC:jl] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "neurotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0019848 +name: obsolete conotoxin activity +namespace: molecular_function +def: "OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "conotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0019855 +consider: GO:0046929 + +[Term] +id: GO:0019849 +name: obsolete cytotoxin activity +namespace: molecular_function +def: "OBSOLETE. Acts as to cause injury to other living cells." [GOC:jl] +comment: This term was made obsolete because it represents a class of gene products. +synonym: "cytotoxin activity" EXACT [] +is_obsolete: true +consider: GO:0009405 +consider: GO:0090729 + +[Term] +id: GO:0019852 +name: L-ascorbic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species." [GOC:jl, ISBN:0198506732] +synonym: "ascorbate metabolic process" EXACT [] +synonym: "ascorbate metabolism" EXACT [] +synonym: "L-ascorbic acid metabolism" EXACT [] +synonym: "vitamin C metabolic process" EXACT [] +synonym: "vitamin C metabolism" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0019853 +name: L-ascorbic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions." [GOC:ma, ISBN:0198547684] +synonym: "ascorbate biosynthesis" EXACT [] +synonym: "ascorbate biosynthetic process" EXACT [] +synonym: "L-ascorbic acid anabolism" EXACT [] +synonym: "L-ascorbic acid biosynthesis" EXACT [] +synonym: "L-ascorbic acid formation" EXACT [] +synonym: "L-ascorbic acid synthesis" EXACT [] +synonym: "vitamin C biosynthesis" EXACT [] +synonym: "vitamin C biosynthetic process" EXACT [] +xref: MetaCyc:PWY-882 +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0019852 ! L-ascorbic acid metabolic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0019854 +name: L-ascorbic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions." [GOC:go_curators] +synonym: "ascorbate catabolic process" EXACT [] +synonym: "ascorbate catabolism" EXACT [] +synonym: "L-ascorbic acid breakdown" EXACT [] +synonym: "L-ascorbic acid catabolism" EXACT [] +synonym: "L-ascorbic acid degradation" EXACT [] +synonym: "vitamin C catabolic process" EXACT [] +synonym: "vitamin C catabolism" EXACT [] +xref: MetaCyc:PWY0-301 +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0019852 ! L-ascorbic acid metabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0046365 ! monosaccharide catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0019855 +name: calcium channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of a calcium channel." [GOC:mah] +is_a: GO:0005246 ! calcium channel regulator activity +is_a: GO:0008200 ! ion channel inhibitor activity +relationship: negatively_regulates GO:0005262 ! calcium channel activity + +[Term] +id: GO:0019856 +name: pyrimidine nucleobase biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." [GOC:go_curators] +synonym: "pyrimidine base anabolism" EXACT [] +synonym: "pyrimidine base biosynthesis" EXACT [] +synonym: "pyrimidine base biosynthetic process" EXACT [GOC:go_curators] +synonym: "pyrimidine base formation" EXACT [] +synonym: "pyrimidine base synthesis" EXACT [] +is_a: GO:0006206 ! pyrimidine nucleobase metabolic process +is_a: GO:0046112 ! nucleobase biosynthetic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process + +[Term] +id: GO:0019857 +name: 5-methylcytosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA." [GOC:ai] +synonym: "5-methylcytosine metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0019858 +name: cytosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives." [GOC:ai] +synonym: "cytosine metabolism" EXACT [] +is_a: GO:0006206 ! pyrimidine nucleobase metabolic process + +[Term] +id: GO:0019859 +name: thymine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base." [GOC:go_curators] +synonym: "thymine metabolism" EXACT [] +is_a: GO:0006206 ! pyrimidine nucleobase metabolic process + +[Term] +id: GO:0019860 +name: uracil metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA." [GOC:go_curators] +synonym: "uracil metabolism" EXACT [] +is_a: GO:0006206 ! pyrimidine nucleobase metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0019861 +name: obsolete flagellum +namespace: cellular_component +alt_id: GO:0008223 +def: "OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium." [UniProtKB-KW:KW-0282] +comment: This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum ; GO:0009288'. +synonym: "flagellum" EXACT [] +xref: Wikipedia:Flagellum +is_obsolete: true +consider: GO:0005929 +consider: GO:0009288 + +[Term] +id: GO:0019862 +name: IgA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype." [GOC:add, ISBN:0781735149] +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0019863 +name: IgE binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype." [GOC:add, ISBN:0781735149] +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0019864 +name: IgG binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype." [GOC:add, ISBN:0781735149] +subset: goslim_chembl +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0019865 +name: immunoglobulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin." [GOC:ma] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0019866 +name: organelle inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites." [GOC:mah] +comment: See also the cellular component term 'outer membrane ; GO:0019867'. +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0031967 ! organelle envelope + +[Term] +id: GO:0019867 +name: outer membrane +namespace: cellular_component +def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators] +subset: goslim_metagenomics +is_a: GO:0016020 ! membrane + +[Term] +id: GO:0019869 +name: chloride channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of a chloride channel." [GOC:mah] +is_a: GO:0008200 ! ion channel inhibitor activity +is_a: GO:0017081 ! chloride channel regulator activity +relationship: negatively_regulates GO:0005254 ! chloride channel activity + +[Term] +id: GO:0019870 +name: potassium channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of a potassium channel." [GOC:mah] +is_a: GO:0008200 ! ion channel inhibitor activity +is_a: GO:0015459 ! potassium channel regulator activity +relationship: negatively_regulates GO:0005267 ! potassium channel activity + +[Term] +id: GO:0019871 +name: sodium channel inhibitor activity +namespace: molecular_function +alt_id: GO:0019868 +def: "Stops, prevents, or reduces the activity of a sodium channel." [GOC:mah] +is_a: GO:0008200 ! ion channel inhibitor activity +is_a: GO:0017080 ! sodium channel regulator activity +relationship: negatively_regulates GO:0005272 ! sodium channel activity + +[Term] +id: GO:0019872 +name: streptomycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome." [GOC:curators] +synonym: "streptomycin anabolism" EXACT [] +synonym: "streptomycin biosynthesis" EXACT [] +synonym: "streptomycin formation" EXACT [] +synonym: "streptomycin synthesis" EXACT [] +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0046343 ! streptomycin metabolic process + +[Term] +id: GO:0019873 +name: obsolete tellurium sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "tellurium sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046690 + +[Term] +id: GO:0019874 +name: 6-aminohexanoate-cyclic-dimer hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate." [EC:3.5.2.12, RHEA:16225] +synonym: "1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity" EXACT [EC:3.5.2.12] +xref: EC:3.5.2.12 +xref: KEGG_REACTION:R03448 +xref: MetaCyc:3.5.2.12-RXN +xref: RHEA:16225 +xref: UM-BBD_reactionID:r1097 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0019875 +name: 6-aminohexanoate-dimer hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate." [EC:3.5.1.46] +synonym: "6-aminohexanoic acid oligomer hydrolase activity" EXACT [EC:3.5.1.46] +synonym: "N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity" EXACT [EC:3.5.1.46] +xref: EC:3.5.1.46 +xref: MetaCyc:RXN-3962 +xref: RHEA:21364 +xref: UM-BBD_enzymeID:e0673 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0019876 +name: nylon catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids." [UniProtKB-KW:KW-0549] +synonym: "nylon breakdown" EXACT [] +synonym: "nylon catabolism" EXACT [] +synonym: "nylon degradation" EXACT [] +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042198 ! nylon metabolic process + +[Term] +id: GO:0019877 +name: diaminopimelate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls." [GOC:ma, ISBN:0198547684] +synonym: "diaminopimelate anabolism" EXACT [] +synonym: "diaminopimelate biosynthesis" EXACT [] +synonym: "diaminopimelate formation" EXACT [] +synonym: "diaminopimelate synthesis" EXACT [] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046451 ! diaminopimelate metabolic process + +[Term] +id: GO:0019878 +name: lysine biosynthetic process via aminoadipic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway." [GOC:go_curators] +synonym: "lysine anabolism via aminoadipic acid" EXACT [] +synonym: "lysine biosynthesis, aminoadipic acid pathway" EXACT [] +synonym: "lysine biosynthesis, aminoadipic pathway" EXACT [] +synonym: "lysine biosynthetic process, aminoadipic acid pathway" EXACT [] +synonym: "lysine biosynthetic process, aminoadipic pathway" EXACT [] +synonym: "lysine formation via aminoadipic acid" EXACT [] +synonym: "lysine synthesis via aminoadipic acid" EXACT [] +is_a: GO:0009085 ! lysine biosynthetic process + +[Term] +id: GO:0019879 +name: peptidyl-thyronine biosynthetic process from peptidyl-tyrosine +namespace: biological_process +def: "The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine." [GOC:jsg] +comment: See also the biological process term 'peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine ; GO:0018250'. +synonym: "peptidyl-thyronine anabolism from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-thyronine formation from peptidyl-tyrosine" EXACT [] +synonym: "peptidyl-thyronine synthesis from peptidyl-tyrosine" EXACT [] +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0019880 +name: obsolete bacteriocin susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "bacteriocin susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046678 + +[Term] +id: GO:0019881 +name: obsolete streptomycin susceptibility/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. +synonym: "streptomycin susceptibility/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046679 + +[Term] +id: GO:0019882 +name: antigen processing and presentation +namespace: biological_process +alt_id: GO:0030333 +def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] +synonym: "antigen presentation" EXACT [] +synonym: "antigen processing" EXACT [] +xref: Wikipedia:Antigen_presentation +is_a: GO:0002376 ! immune system process + +[Term] +id: GO:0019883 +name: antigen processing and presentation of endogenous antigen +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] +synonym: "antigen presentation, endogenous antigen" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0019884 +name: antigen processing and presentation of exogenous antigen +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] +synonym: "antigen presentation, exogenous antigen" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0019885 +name: antigen processing and presentation of endogenous peptide antigen via MHC class I +namespace: biological_process +alt_id: GO:0048004 +def: "The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "antigen presentation, endogenous peptide antigen" BROAD [] +synonym: "antigen processing, endogenous antigen via major histocompatibility complex class I" BROAD [] +synonym: "antigen processing, endogenous antigen via MHC class I" BROAD [] +synonym: "endogenous peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +is_a: GO:0002483 ! antigen processing and presentation of endogenous peptide antigen + +[Term] +id: GO:0019886 +name: antigen processing and presentation of exogenous peptide antigen via MHC class II +namespace: biological_process +alt_id: GO:0042591 +alt_id: GO:0048005 +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "antigen presentation, exogenous antigen via MHC class II" BROAD [] +synonym: "antigen presentation, exogenous peptide antigen" BROAD [] +synonym: "antigen processing, exogenous antigen via major histocompatibility complex class II" BROAD [] +synonym: "exogenous peptide antigen processing and presentation via MHC class II" EXACT [] +is_a: GO:0002478 ! antigen processing and presentation of exogenous peptide antigen +is_a: GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II + +[Term] +id: GO:0019887 +name: protein kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] +is_a: GO:0019207 ! kinase regulator activity +relationship: has_part GO:0019901 ! protein kinase binding +relationship: part_of GO:0045859 ! regulation of protein kinase activity +relationship: regulates GO:0004672 ! protein kinase activity + +[Term] +id: GO:0019888 +name: protein phosphatase regulator activity +namespace: molecular_function +alt_id: GO:0008599 +alt_id: GO:0008601 +alt_id: GO:0030359 +alt_id: GO:0030362 +def: "Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule." [GOC:ai] +synonym: "calcineurin regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "calcineurin, intrinsic regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase 2 regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase 2, intrinsic regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase 3 regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase 3, intrinsic regulator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase type 1 regulator activity" NARROW [] +synonym: "protein phosphatase type 1, intrinsic regulator activity" NARROW [] +synonym: "protein phosphatase type 2A regulator activity" NARROW [] +synonym: "protein phosphatase type 2A, intrinsic regulator activity" NARROW [] +synonym: "protein phosphatase type 2B regulator activity" NARROW [] +synonym: "protein phosphatase type 2B, intrinsic regulator activity" NARROW [] +synonym: "protein phosphatase type 4 regulator activity" NARROW [] +synonym: "protein phosphatase type 4, intrinsic regulator activity" NARROW [] +xref: Reactome:R-HSA-180038 "DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function" +is_a: GO:0019208 ! phosphatase regulator activity +relationship: has_part GO:0019903 ! protein phosphatase binding +relationship: part_of GO:0043666 ! regulation of phosphoprotein phosphatase activity + +[Term] +id: GO:0019889 +name: pteridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group." [GOC:go_curators, ISBN:0198506732] +synonym: "pteridine metabolism" EXACT [] +is_a: GO:0042558 ! pteridine-containing compound metabolic process + +[Term] +id: GO:0019893 +name: obsolete DNA replication inhibitor +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it does not represent a true molecular function. +synonym: "DNA replication inhibitor" EXACT [] +is_obsolete: true +replaced_by: GO:0008156 + +[Term] +id: GO:0019894 +name: kinesin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation." [GOC:curators, PMID:8606779] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0019895 +name: obsolete kinesin-associated mitochondrial adaptor activity +namespace: molecular_function +def: "OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria." [PMID:12495622] +comment: This term was obsoleted because it represents the function of a specific protein. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17668 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0019896 +name: axonal transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in nerve cell axons." [GOC:ai] +subset: goslim_synapse +synonym: "axon transport of mitochondria" EXACT [] +is_a: GO:0047497 ! mitochondrion transport along microtubule +is_a: GO:0098930 ! axonal transport +relationship: occurs_in GO:1904115 ! axon cytoplasm + +[Term] +id: GO:0019897 +name: extrinsic component of plasma membrane +namespace: cellular_component +alt_id: GO:0000157 +def: "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:curators, GOC:dos] +synonym: "extrinsic to plasma membrane" EXACT [] +synonym: "juxtamembrane" BROAD [] +synonym: "peripheral plasma membrane protein" EXACT [] +is_a: GO:0019898 ! extrinsic component of membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0019898 +name: extrinsic component of membrane +namespace: cellular_component +alt_id: GO:0030396 +def: "The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:jl, GOC:mah] +comment: Note that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions. +subset: goslim_metagenomics +synonym: "extrinsic to membrane" EXACT [] +synonym: "peripheral membrane protein" EXACT [] +xref: Wikipedia:Peripheral_membrane_protein +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016020 ! membrane + +[Term] +id: GO:0019899 +name: enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any enzyme." [GOC:jl] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0019900 +name: kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group." [GOC:jl] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0019901 +name: protein kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate." [GOC:jl] +is_a: GO:0019900 ! kinase binding + +[Term] +id: GO:0019902 +name: phosphatase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any phosphatase." [GOC:jl] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0019903 +name: protein phosphatase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein phosphatase." [GOC:jl] +is_a: GO:0019902 ! phosphatase binding + +[Term] +id: GO:0019904 +name: protein domain specific binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a specific domain of a protein." [GOC:go_curators] +subset: goslim_chembl +synonym: "protein domain-specific binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0019905 +name: syntaxin binding +namespace: molecular_function +alt_id: GO:0030347 +alt_id: GO:0030349 +alt_id: GO:0050430 +alt_id: GO:0051535 +def: "Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse." [ISBN:0198506732] +synonym: "syntaxin-13 binding" NARROW [] +synonym: "syntaxin-2 binding" NARROW [] +synonym: "syntaxin-5 binding" NARROW [] +synonym: "syntaxin-6 binding" NARROW [] +is_a: GO:0000149 ! SNARE binding + +[Term] +id: GO:0019907 +name: cyclin-dependent protein kinase activating kinase holoenzyme complex +namespace: cellular_component +def: "A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH." [GOC:bhm, PMID:8752210] +synonym: "CAK complex" EXACT [] +synonym: "CDK-activating kinase complex" EXACT [] +xref: IntAct:EBI-1246076 +xref: IntAct:EBI-9868598 +is_a: GO:0019908 ! nuclear cyclin-dependent protein kinase holoenzyme complex +is_a: GO:0032806 ! carboxy-terminal domain protein kinase complex +is_a: GO:0150005 ! enzyme activator complex + +[Term] +id: GO:0019908 +name: nuclear cyclin-dependent protein kinase holoenzyme complex +namespace: cellular_component +def: "Cyclin-dependent protein kinase (CDK) complex found in the nucleus." [GOC:krc] +synonym: "CDK holoenzyme" BROAD [] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +intersection_of: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0019909 +name: [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity +namespace: molecular_function +def: "Modification of the activity of the enzyme [pyruvate dehydrogenase (lipoamide)] phosphatase." [EC:3.1.3.43, GOC:ai] +synonym: "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity" NARROW [] +is_a: GO:0019888 ! protein phosphatase regulator activity +relationship: regulates GO:0004741 ! [pyruvate dehydrogenase (lipoamide)] phosphatase activity + +[Term] +id: GO:0019910 +name: mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex +namespace: cellular_component +def: "A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus." [GOC:mtg_sensu, PMID:9395502] +comment: See also the cellular component term 'mitochondrial pyruvate dehydrogenase complex ; GO:0005967'. +is_a: GO:0045253 ! pyruvate dehydrogenase (lipoamide) phosphatase complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0045253 ! pyruvate dehydrogenase (lipoamide) phosphatase complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0019911 +name: structural constituent of myelin sheath +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve." [GOC:mah] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0043209 ! myelin sheath +relationship: occurs_in GO:0043209 ! myelin sheath + +[Term] +id: GO:0019912 +name: cyclin-dependent protein kinase activating kinase activity +namespace: molecular_function +alt_id: GO:0019913 +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK)." [GOC:go_curators] +synonym: "CAK" EXACT [] +synonym: "cdk-activating kinase activity" EXACT [] +synonym: "cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity" EXACT [] +is_a: GO:0004672 ! protein kinase activity +is_a: GO:0030295 ! protein kinase activator activity +relationship: part_of GO:1904031 ! positive regulation of cyclin-dependent protein kinase activity + +[Term] +id: GO:0019914 +name: cyclin-dependent protein kinase activating kinase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase." [GOC:ai] +synonym: "cyclin-dependent protein kinase activating kinase, intrinsic regulator activity" NARROW [] +xref: EC:2.7.1 +is_a: GO:0019887 ! protein kinase regulator activity +relationship: regulates GO:0019912 ! cyclin-dependent protein kinase activating kinase activity + +[Term] +id: GO:0019915 +name: lipid storage +namespace: biological_process +def: "The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development." [GOC:dph, GOC:mah, GOC:tb, PMID:11102830] +synonym: "lipid retention" EXACT [GOC:dph, GOC:tb] +synonym: "lipid sequestering" NARROW [GOC:dph, GOC:tb] +synonym: "lipid sequestration" NARROW [GOC:dph, GOC:tb] +synonym: "retention of lipids" EXACT [GOC:dph, GOC:tb] +synonym: "sequestering of lipids" NARROW [GOC:dph, GOC:tb] +synonym: "sequestration of lipid" NARROW [GOC:dph, GOC:tb] +synonym: "sequestration of lipids" EXACT [GOC:dph, GOC:tb] +synonym: "storage of lipids" EXACT [] +is_a: GO:0051235 ! maintenance of location +relationship: part_of GO:0010876 ! lipid localization + +[Term] +id: GO:0019916 +name: peptidyl-D-alanine racemization, direct +namespace: biological_process +def: "The racemization of peptidyl-alanine." [RESID:AA0191] +xref: RESID:AA0191 +is_a: GO:0019122 ! peptidyl-D-alanine racemization + +[Term] +id: GO:0019917 +name: peptidyl-D-alanine racemization via peptidyl-L-serine +namespace: biological_process +def: "The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine." [RESID:AA0191] +xref: RESID:AA0191 +is_a: GO:0019122 ! peptidyl-D-alanine racemization + +[Term] +id: GO:0019918 +name: peptidyl-arginine methylation, to symmetrical-dimethyl arginine +namespace: biological_process +def: "The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine." [RESID:AA0067, RESID:AA0069] +xref: RESID:AA0067 +xref: RESID:AA0069 +is_a: GO:0035247 ! peptidyl-arginine omega-N-methylation + +[Term] +id: GO:0019919 +name: peptidyl-arginine methylation, to asymmetrical-dimethyl arginine +namespace: biological_process +def: "The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine." [RESID:AA0068, RESID:AA0069] +synonym: "peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine" EXACT [] +xref: RESID:AA0068 +xref: RESID:AA0069 +is_a: GO:0035247 ! peptidyl-arginine omega-N-methylation + +[Term] +id: GO:0019920 +name: peptidyl-1-thioglycine biosynthetic process, internal +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide." [GOC:go_curators, http://www.uni-marburg.de/mpi/thauer/thauer_res.html, RESID:AA0265] +synonym: "peptidyl-1-thioglycine anabolism, internal" EXACT [] +synonym: "peptidyl-1-thioglycine formation, internal" EXACT [] +synonym: "peptidyl-1-thioglycine synthesis, internal" EXACT [] +xref: RESID:AA0265 +is_a: GO:0018173 ! peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine + +[Term] +id: GO:0019921 +name: peptidyl-1-thioglycine biosynthetic process, carboxy-terminal +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond." [GOC:go_curators, http://www.uni-marburg.de/mpi/thauer/thauer_res.html, RESID:AA0265] +synonym: "peptidyl-1-thioglycine anabolism, carboxy-terminal" EXACT [] +synonym: "peptidyl-1-thioglycine formation, carboxy-terminal" EXACT [] +synonym: "peptidyl-1-thioglycine synthesis, carboxy-terminal" EXACT [] +xref: RESID:AA0265 +is_a: GO:0018173 ! peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine + +[Term] +id: GO:0019922 +name: protein-chromophore linkage via peptidyl-cysteine +namespace: biological_process +def: "The covalent linking of a chromophore to a protein via peptidyl-cysteines." [GOC:ma] +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0019923 +name: alpha-1-microglobulin-chromophore linkage +namespace: biological_process +def: "The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds." [RESID:AA0224] +xref: RESID:AA0224 +is_a: GO:0019922 ! protein-chromophore linkage via peptidyl-cysteine + +[Term] +id: GO:0019926 +name: peptidyl-tryptophan oxidation to tryptophyl quinone +namespace: biological_process +def: "The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine." [PMID:2028257, RESID:AA0148] +comment: See also the biological process term 'peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone ; GO:0018069'. +is_a: GO:0018158 ! protein oxidation +is_a: GO:0018211 ! peptidyl-tryptophan modification +relationship: part_of GO:0018069 ! peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone + +[Term] +id: GO:0019927 +name: peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone +namespace: biological_process +def: "The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase." [PDB:1JJU, PMID:11555656, PMID:11717396, RESID:AA0313] +xref: RESID:AA0313 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0019928 +name: peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid +namespace: biological_process +def: "The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid." [PDB:1JJU, PMID:11555656, PMID:11717396, RESID:AA0314] +xref: RESID:AA0314 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018197 ! peptidyl-aspartic acid modification +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0019929 +name: peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid +namespace: biological_process +def: "The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid." [RESID:AA0315] +xref: RESID:AA0315 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018200 ! peptidyl-glutamic acid modification + +[Term] +id: GO:0019930 +name: cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid +namespace: biological_process +def: "The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1." [RESID:AA0316] +synonym: "cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester anabolism from peptidyl-aspartic acid" EXACT [] +synonym: "cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester formation from peptidyl-aspartic acid" EXACT [] +synonym: "cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester synthesis from peptidyl-aspartic acid" EXACT [] +xref: RESID:AA0316 +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0019931 +name: protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine +namespace: biological_process +def: "The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine." [RESID:AA0312] +xref: RESID:AA0312 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0019932 +name: second-messenger-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." [GOC:signaling, ISBN:0815316194, PMID:15221855, Wikipedia:Second_messenger_system] +synonym: "second messenger mediated signaling" EXACT [] +synonym: "second messenger mediated signalling" EXACT [] +synonym: "second messenger-mediated signaling" EXACT [] +synonym: "second messenger-mediated signalling" EXACT [] +synonym: "second-messenger-mediated signal transduction" EXACT [GOC:signaling] +synonym: "second-messenger-mediated signalling" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0019933 +name: cAMP-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell." [GOC:signaling] +synonym: "3',5' cAMP-mediated signaling" EXACT [] +synonym: "3',5' cAMP-mediated signalling" EXACT [] +synonym: "3',5'-cAMP-mediated signaling" EXACT [] +synonym: "3',5'-cAMP-mediated signalling" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-mediated signaling" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate-mediated signalling" EXACT [] +synonym: "cAMP signaling" EXACT [] +synonym: "cAMP signalling" EXACT [] +synonym: "cAMP-mediated signal transduction" EXACT [] +synonym: "cAMP-mediated signalling" EXACT [] +synonym: "cyclic AMP-mediated signaling" EXACT [] +synonym: "cyclic AMP-mediated signalling" EXACT [] +is_a: GO:0019935 ! cyclic-nucleotide-mediated signaling + +[Term] +id: GO:0019934 +name: cGMP-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell." [GOC:signaling] +synonym: "cGMP-mediated signalling" EXACT [] +is_a: GO:0019935 ! cyclic-nucleotide-mediated signaling + +[Term] +id: GO:0019935 +name: cyclic-nucleotide-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell." [GOC:signaling] +synonym: "cyclic-nucleotide-mediated signalling" EXACT [] +is_a: GO:0019932 ! second-messenger-mediated signaling + +[Term] +id: GO:0019936 +name: obsolete inositol phospholipid-mediated signaling +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ceb] +comment: This term was made obsolete because it did not adequately describe phosphoinositide-mediated signaling. +synonym: "inositol phospholipid-mediated signaling" EXACT [] +synonym: "inositol phospholipid-mediated signalling" EXACT [] +is_obsolete: true +consider: GO:0048016 +consider: GO:0048017 + +[Term] +id: GO:0019937 +name: protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic +namespace: biological_process +def: "The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid." [RESID:AA0294] +xref: RESID:AA0294 +is_a: GO:0018419 ! protein catenane formation +is_a: GO:0018420 ! peptide cross-linking via N6-(L-isoaspartyl)-L-lysine + +[Term] +id: GO:0019938 +name: peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic +namespace: biological_process +alt_id: GO:0042266 +def: "The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions." [RESID:AA0294] +xref: RESID:AA0294 +is_a: GO:0018420 ! peptide cross-linking via N6-(L-isoaspartyl)-L-lysine + +[Term] +id: GO:0019939 +name: peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically." [RESID:AA0308] +synonym: "peptidyl-S-palmitoleyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-palmitoleyl-L-cysteine formation from peptidyl-cysteine" EXACT [] +synonym: "peptidyl-S-palmitoleyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] +xref: RESID:AA0308 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0045234 ! protein palmitoleylation + +[Term] +id: GO:0019940 +name: obsolete SUMO-dependent protein catabolic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it does not reflect an accurate biological process, as sumoylation of a protein does not lead to catabolism of that protein. +synonym: "SUMO-dependent protein breakdown" EXACT [] +synonym: "SUMO-dependent protein catabolic process" EXACT [] +synonym: "SUMO-dependent protein catabolism" EXACT [] +synonym: "SUMO-dependent protein degradation" EXACT [] +is_obsolete: true +consider: GO:0016925 +consider: GO:0016926 + +[Term] +id: GO:0019941 +name: modification-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein." [GOC:go_curators] +synonym: "modification-dependent protein breakdown" EXACT [] +synonym: "modification-dependent protein catabolism" EXACT [] +synonym: "modification-dependent protein degradation" EXACT [] +synonym: "modification-dependent proteolysis" EXACT [GOC:rl] +synonym: "modification-initiated protein catabolic process" EXACT [GOC:rl] +synonym: "modification-initiated protein catabolism" EXACT [GOC:rl] +synonym: "modification-initiated proteolysis" EXACT [GOC:rl] +synonym: "protein degradation tagging activity" RELATED [] +synonym: "protein-ligand-dependent protein catabolic process" NARROW [] +synonym: "protein-ligand-dependent protein catabolism" NARROW [] +is_a: GO:0043632 ! modification-dependent macromolecule catabolic process +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process + +[Term] +id: GO:0019942 +name: obsolete NEDD8 class-dependent protein catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein." [GOC:jl] +comment: This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction. +synonym: "NEDD8 class-dependent protein breakdown" EXACT [] +synonym: "NEDD8 class-dependent protein catabolic process" EXACT [] +synonym: "NEDD8 class-dependent protein catabolism" EXACT [] +synonym: "NEDD8 class-dependent protein degradation" EXACT [] +synonym: "RUB1-dependent protein catabolic process" EXACT [] +synonym: "RUB1-dependent protein catabolism" EXACT [] +synonym: "RUB1-dependent protein degradation" EXACT [] +is_obsolete: true +consider: GO:0045116 + +[Term] +id: GO:0019948 +name: SUMO activating enzyme activity +namespace: molecular_function +alt_id: GO:0017115 +def: "Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:rn, PMID:10187858, PMID:11265250] +synonym: "SMT3 activating enzyme" EXACT [] +synonym: "SUMO E1 activator enzyme" EXACT [] +xref: Reactome:R-HSA-2990833 "Conjugation of SUMO1 to UBA2:SAE1" +xref: Reactome:R-HSA-2993781 "Conjugation of SUMO3 to UBA2:SAE1" +xref: Reactome:R-HSA-2993784 "Conjugation of SUMO2 to UBA2:SAE1" +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0019950 +name: SMT3-dependent protein catabolic process +namespace: biological_process +alt_id: GO:0019946 +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein." [GOC:jl, PMID:9435231] +synonym: "SMT3-dependent protein breakdown" EXACT [] +synonym: "SMT3-dependent protein catabolism" EXACT [] +synonym: "SMT3-dependent protein degradation" EXACT [] +is_a: GO:0019941 ! modification-dependent protein catabolic process + +[Term] +id: GO:0019951 +name: Smt3-protein conjugation +namespace: biological_process +alt_id: GO:0019947 +def: "The covalent addition to a protein of Smt3, a ubiquitin-like protein." [GOC:jl] +synonym: "Smt3p-protein conjugation" EXACT [] +is_a: GO:0032446 ! protein modification by small protein conjugation +relationship: part_of GO:0019950 ! SMT3-dependent protein catabolic process + +[Term] +id: GO:0019953 +name: sexual reproduction +namespace: biological_process +def: "A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny." [GOC:jl, GOC:kmv, GOC:krc, GOC:tb, ISBN:0387520546, Wikipedia:Sexual_reproduction] +comment: Sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. +xref: Wikipedia:Sexual_reproduction +is_a: GO:0000003 ! reproduction +is_a: GO:0044703 ! multi-organism reproductive process + +[Term] +id: GO:0019954 +name: asexual reproduction +namespace: biological_process +def: "The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process." [ISBN:0387520546] +synonym: "parthenogenesis" RELATED [Wikipedia:Parthenogenesis] +xref: Wikipedia:Asexual_reproduction +is_a: GO:0000003 ! reproduction + +[Term] +id: GO:0019955 +name: cytokine binding +namespace: molecular_function +alt_id: GO:0019965 +def: "Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." [GOC:ai, GOC:bf, ISBN:0198599471] +synonym: "IL binding" NARROW [] +synonym: "interleukin binding" NARROW [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0019956 +name: chemokine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:ai, GOC:BHF, GOC:rl, PMID:12183377, Wikipedia:Chemokine] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019957 +name: C-C chemokine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif." [GOC:ai] +is_a: GO:0019956 ! chemokine binding + +[Term] +id: GO:0019958 +name: C-X-C chemokine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif." [GOC:ai] +is_a: GO:0019956 ! chemokine binding + +[Term] +id: GO:0019959 +name: interleukin-8 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-8." [GOC:jl] +synonym: "IL-8 binding" EXACT [] +is_a: GO:0019958 ! C-X-C chemokine binding + +[Term] +id: GO:0019960 +name: C-X3-C chemokine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif." [GOC:ai] +is_a: GO:0019956 ! chemokine binding + +[Term] +id: GO:0019961 +name: interferon binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent." [PMID:9607096, Wikipedia:Interferon] +synonym: "IFN binding" EXACT [GOC:mah] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019962 +name: type I interferon binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834] +synonym: "interferon-alpha binding" NARROW [] +synonym: "interferon-alpha/beta binding" NARROW [] +synonym: "interferon-beta binding" NARROW [] +synonym: "interferon-delta binding" NARROW [] +synonym: "interferon-epsilon binding" NARROW [] +synonym: "interferon-kappa binding" NARROW [] +synonym: "interferon-omega binding" NARROW [] +synonym: "interferon-tau binding" NARROW [] +synonym: "interferon-zeta binding" NARROW [] +synonym: "type I IFN binding" EXACT [GOC:mah] +is_a: GO:0019961 ! interferon binding + +[Term] +id: GO:0019964 +name: interferon-gamma binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interferon-gamma. Interferon gamma is the only member of the type II interferon found so far." [GOC:add, GOC:ai, ISBN:0126896631, PMID:15546383, PR:000000017] +synonym: "IFN-gamma binding" EXACT [GOC:mah, PR:000000017] +synonym: "IFNG binding" EXACT [GOC:mah] +synonym: "type II interferon binding" BROAD [PMID:15546383, PR:000024990] +is_a: GO:0019961 ! interferon binding + +[Term] +id: GO:0019966 +name: interleukin-1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-1." [GOC:jl, ISBN:0198506732] +synonym: "IL-1 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019969 +name: interleukin-10 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-10." [GOC:jl] +synonym: "IL-10 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019970 +name: interleukin-11 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-11." [GOC:jl] +synonym: "IL-11 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019972 +name: interleukin-12 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-12." [GOC:jl] +synonym: "IL-12 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019973 +name: interleukin-13 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-13." [GOC:jl] +synonym: "IL-13 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019974 +name: interleukin-14 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-14." [GOC:jl] +synonym: "IL-14 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019975 +name: interleukin-17 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines." [GOC:add, GOC:jl] +synonym: "IL-17 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019976 +name: interleukin-2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-2." [GOC:jl] +synonym: "IL-2 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019977 +name: interleukin-21 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-21." [GOC:jl] +synonym: "IL-21 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019978 +name: interleukin-3 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-3." [GOC:jl] +synonym: "IL-3 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019979 +name: interleukin-4 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-4." [GOC:jl] +synonym: "IL-4 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019980 +name: interleukin-5 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-5." [GOC:jl] +synonym: "IL-5 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019981 +name: interleukin-6 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-6." [GOC:jl] +synonym: "IL-6 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019982 +name: interleukin-7 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-7." [GOC:jl] +synonym: "IL-7 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019983 +name: interleukin-9 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-9." [GOC:jl] +synonym: "IL-9 binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0019985 +name: translesion synthesis +namespace: biological_process +def: "The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide." [GOC:elh, GOC:vw, PMID:10535901] +synonym: "bypass DNA synthesis" EXACT [GOC:elh] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +is_a: GO:0006301 ! postreplication repair + +[Term] +id: GO:0019987 +name: obsolete negative regulation of anti-apoptosis +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis." [GOC:go_curators, GOC:mtg_apoptosis] +comment: This term was made obsolete because it was ill-defined. +synonym: "down regulation of anti-apoptosis" EXACT [] +synonym: "down-regulation of anti-apoptosis" EXACT [] +synonym: "downregulation of anti-apoptosis" EXACT [] +synonym: "inhibition of anti-apoptosis" NARROW [] +synonym: "negative regulation of anti-apoptosis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0019988 +name: charged-tRNA amino acid modification +namespace: biological_process +alt_id: GO:0030630 +def: "The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine." [GOC:jsg] +synonym: "charged tRNA amino acid modification" EXACT [] +synonym: "charged tRNA modification" EXACT [] +synonym: "charged-tRNA modification" RELATED [] +synonym: "pre-translational amino acid modification" EXACT [] +synonym: "pre-translational protein modification" EXACT [] +synonym: "pretranslation protein modification" EXACT [] +synonym: "pretranslational amino acid modification" EXACT [] +is_a: GO:0006400 ! tRNA modification +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0019990 +name: pteridine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group." [ISBN:0198506732] +synonym: "pteridine breakdown" EXACT [] +synonym: "pteridine catabolism" EXACT [] +synonym: "pteridine degradation" EXACT [] +is_a: GO:0019889 ! pteridine metabolic process +is_a: GO:0042560 ! pteridine-containing compound catabolic process + +[Term] +id: GO:0019991 +name: septate junction assembly +namespace: biological_process +def: "The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space." [GOC:ai, PMID:5272312] +is_a: GO:0120192 ! tight junction assembly +relationship: part_of GO:0043297 ! apical junction assembly + +[Term] +id: GO:0019992 +name: diacylglycerol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids." [GOC:ma] +is_a: GO:0008289 ! lipid binding + +[Term] +id: GO:0020002 +name: host cell plasma membrane +namespace: cellular_component +def: "The plasma membrane surrounding a host cell." [GOC:mb] +is_a: GO:0033644 ! host cell membrane + +[Term] +id: GO:0020003 +name: symbiont-containing vacuole +namespace: cellular_component +def: "Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont." [GOC:jl, GOC:mb] +comment: Note that this term does not have a relationship to 'vacuole ; GO:0005773' because it does not fit the definition of a vacuole; the parasitophorous vacuole was so named because it resembles a vacuole in the microscope. +synonym: "bacterium-containing vacuole" NARROW [PMID:22042847] +synonym: "parasitophorous vacuole" EXACT [] +synonym: "pathogen-occupied vacuole" NARROW [PMID:24034612] +synonym: "Salmonella-containing vacuole" NARROW [PMID:10449405, PMID:15121880] +synonym: "SCV" EXACT [PMID:10449405, PMID:15121880] +is_a: GO:0033655 ! host cell cytoplasm part +is_a: GO:0065010 ! extracellular membrane-bounded organelle + +[Term] +id: GO:0020004 +name: symbiont-containing vacuolar space +namespace: cellular_component +def: "The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane." [GOC:jl, GOC:mb] +synonym: "parasitophorous vacuolar space" EXACT [] +synonym: "symbiont-containing vacuole space" RELATED [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0020003 ! symbiont-containing vacuole + +[Term] +id: GO:0020005 +name: symbiont-containing vacuole membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont." [GOC:jl, GOC:mb] +synonym: "parasitophorous vacuolar membrane" EXACT [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0020003 ! symbiont-containing vacuole + +[Term] +id: GO:0020006 +name: symbiont-containing vacuolar membrane network +namespace: cellular_component +def: "Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm." [GOC:jl, PMID:3528173] +synonym: "parasitophorous vacuolar membrane network" EXACT [] +synonym: "symbiont-containing vacuole membrane network" EXACT [] +synonym: "tubulovesicular network" NARROW [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0020005 ! symbiont-containing vacuole membrane + +[Term] +id: GO:0020007 +name: apical complex +namespace: cellular_component +def: "A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation." [GOC:giardia, GOC:mb, PMID:16518471] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045177 ! apical part of cell + +[Term] +id: GO:0020008 +name: rhoptry +namespace: cellular_component +def: "A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole." [ISBN:0521664470, PMID:11801218, PMID:16002398] +synonym: "paired organelles" RELATED [] +synonym: "toxoneme" RELATED [] +xref: Wikipedia:Rhoptry +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020009 +name: microneme +namespace: cellular_component +def: "A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell." [ISBN:0521664470, PMID:11801218] +synonym: "sarconeme" RELATED [] +xref: Wikipedia:Microneme +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020010 +name: conoid +namespace: cellular_component +def: "A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules." [GOC:expert_dr, PMID:11901169, PMID:16518471] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020011 +name: apicoplast +namespace: cellular_component +def: "The plastid organelle found in apicomplexans." [ISBN:0521664470] +xref: Wikipedia:Apicoplast +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0020013 +name: modulation by symbiont of host erythrocyte aggregation +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes." [GOC:add, GOC:dgh, GOC:mb, GOC:pr, PMID:19467172, PMID:21305024] +comment: Please note that this term does not refer to the in vitro assay called erythrocyte rosetting. +synonym: "rosetting" EXACT [] +xref: Wikipedia:Rosetting +is_a: GO:0034118 ! regulation of erythrocyte aggregation +is_a: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0034117 ! erythrocyte aggregation + +[Term] +id: GO:0020014 +name: schizogony +namespace: biological_process +def: "Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously." [GOC:mb] +xref: Wikipedia:Protozoal_merogony +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0020015 +name: glycosome +namespace: cellular_component +def: "A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis." [GOC:mb] +subset: goslim_pir +xref: Wikipedia:Glycosome +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0020016 +name: ciliary pocket +namespace: cellular_component +def: "Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes." [GOC:cilia, GOC:mb] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage. +synonym: "cilial pocket" EXACT [] +synonym: "cilium pocket" EXACT [] +synonym: "flagellar pocket" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium + +[Term] +id: GO:0020018 +name: ciliary pocket membrane +namespace: cellular_component +def: "That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket)." [GOC:cilia, GOC:mb] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage. +synonym: "cilial pocket membrane" EXACT [] +synonym: "cilium pocket membrane" EXACT [] +synonym: "flagellar pocket membrane" EXACT [] +is_a: GO:0060170 ! ciliary membrane +relationship: part_of GO:0020016 ! ciliary pocket + +[Term] +id: GO:0020020 +name: food vacuole +namespace: cellular_component +alt_id: GO:0005772 +def: "Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa." [GOC:mb] +synonym: "digestive vacuole" EXACT [] +is_a: GO:0032010 ! phagolysosome + +[Term] +id: GO:0020022 +name: acidocalcisome +namespace: cellular_component +def: "An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations." [GOC:mb] +subset: goslim_pir +synonym: "metachromatic granule" EXACT [PMID:15738951] +synonym: "polyphosphate vacuole" RELATED [PMID:15738951] +synonym: "volutin granule" EXACT [PMID:15738951] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0020023 +name: kinetoplast +namespace: cellular_component +def: "A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum." [GOC:mb] +xref: Wikipedia:Kinetoplast +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0020025 +name: subpellicular microtubule +namespace: cellular_component +def: "Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid." [GOC:mb, PMID:24800253] +is_a: GO:0005874 ! microtubule +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020026 +name: merozoite dense granule +namespace: cellular_component +def: "Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell." [GOC:mb, GOC:mtg_sensu] +synonym: "dense body" RELATED [] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0020027 +name: hemoglobin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hemoglobin, including its uptake and utilization." [GOC:go_curators, GOC:jl] +synonym: "haemoglobin metabolic process" EXACT [] +synonym: "haemoglobin metabolism" EXACT [] +synonym: "hemoglobin metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0020028 +name: endocytic hemoglobin import into cell +namespace: biological_process +def: "The directed movement of hemoglobin into a cell by receptor-mediated endocytosis." [GOC:mb] +synonym: "endocytic hemoglobin import" RELATED [] +synonym: "haemoglobin uptake" EXACT [] +synonym: "hemoglobin uptake" EXACT [] +is_a: GO:0017038 ! protein import +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0140421 ! endocytic heme import into cell + +[Term] +id: GO:0020030 +name: infected host cell surface knob +namespace: cellular_component +def: "Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species." [GOC:mb] +is_a: GO:0033655 ! host cell cytoplasm part + +[Term] +id: GO:0020031 +name: polar ring of apical complex +namespace: cellular_component +def: "An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite." [GOC:mb, PMID:16518471] +synonym: "anterior polar ring of apical complex" EXACT [] +synonym: "upper polar ring of apical complex" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020032 +name: basal ring of apical complex +namespace: cellular_component +def: "An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite." [GOC:mah, PMID:16518471] +synonym: "lower polar ring of apical complex" EXACT [] +synonym: "posterior polar ring of apical complex" EXACT [] +synonym: "preconoidal ring of apical complex" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0020033 +name: antigenic variation +namespace: biological_process +alt_id: GO:0020034 +def: "Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system." [GOC:mb] +synonym: "surface antigen variation" NARROW [] +xref: Wikipedia:Antigenic_variation +is_a: GO:0042783 ! evasion of host immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18357 xsd:anyURI + +[Term] +id: GO:0020035 +name: cytoadherence to microvasculature, mediated by symbiont protein +namespace: biological_process +alt_id: GO:0043706 +def: "The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte." [GOC:mb, PMID:10362584] +synonym: "cytoadherence to microvasculature, mediated by parasite protein" NARROW [] +synonym: "heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein" NARROW [] +synonym: "parasite-protein-mediated cytoadherence to microvasculature" NARROW [] +synonym: "symbiont-protein-mediated cytoadherence to microvasculature" BROAD [] +is_a: GO:0044406 ! adhesion of symbiont to host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18814 xsd:anyURI + +[Term] +id: GO:0020036 +name: Maurer's cleft +namespace: cellular_component +def: "A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton." [PMID:16705161] +synonym: "Maurers cleft" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part + +[Term] +id: GO:0020037 +name: heme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring." [GOC:ai] +synonym: "haem binding" EXACT [] +is_a: GO:0046906 ! tetrapyrrole binding +is_a: GO:0048037 ! cofactor binding + +[Term] +id: GO:0020038 +name: subpellicular network +namespace: cellular_component +def: "A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton." [PMID:11420112] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0020039 ! pellicle + +[Term] +id: GO:0020039 +name: pellicle +namespace: cellular_component +def: "The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles." [GOC:mah, GOC:mb] +is_a: GO:0110165 ! cellular anatomical entity +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:33154 + +[Term] +id: GO:0021501 +name: prechordal plate formation +namespace: biological_process +def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0021502 +name: neural fold elevation formation +namespace: biological_process +def: "The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0001842 ! neural fold formation + +[Term] +id: GO:0021503 +name: neural fold bending +namespace: biological_process +def: "The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0001842 ! neural fold formation + +[Term] +id: GO:0021504 +name: neural fold hinge point formation +namespace: biological_process +def: "The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:13679871, PMID:15806586] +synonym: "neural fold furrowing" NARROW [GOC:cls] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021503 ! neural fold bending + +[Term] +id: GO:0021505 +name: neural fold folding +namespace: biological_process +def: "The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:13679871, PMID:15806586] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0021503 ! neural fold bending + +[Term] +id: GO:0021506 +name: anterior neuropore closure +namespace: biological_process +def: "The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0021995 ! neuropore closure + +[Term] +id: GO:0021507 +name: posterior neuropore closure +namespace: biological_process +def: "The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0060608 ! cell-cell adhesion involved in neural tube closure +relationship: part_of GO:0021995 ! neuropore closure + +[Term] +id: GO:0021508 +name: floor plate formation +namespace: biological_process +def: "The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007418 ! ventral midline development +relationship: part_of GO:0033505 ! floor plate morphogenesis + +[Term] +id: GO:0021509 +name: roof plate formation +namespace: biological_process +def: "The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15936325] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0001841 ! neural tube formation + +[Term] +id: GO:0021510 +name: spinal cord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0021511 +name: spinal cord patterning +namespace: biological_process +def: "The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0021510 ! spinal cord development + +[Term] +id: GO:0021512 +name: spinal cord anterior/posterior patterning +namespace: biological_process +def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "spinal cord anterior-posterior patterning" EXACT [] +synonym: "spinal cord rostrocaudal patterning" RELATED [GOC:dph] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0021511 ! spinal cord patterning + +[Term] +id: GO:0021513 +name: spinal cord dorsal/ventral patterning +namespace: biological_process +def: "The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "spinal cord dorsal-ventral patterning" EXACT [] +synonym: "spinal cord dorsoventral patterning" EXACT [GOC:mah] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0021511 ! spinal cord patterning + +[Term] +id: GO:0021514 +name: ventral spinal cord interneuron differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021517 ! ventral spinal cord development + +[Term] +id: GO:0021515 +name: cell differentiation in spinal cord +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021510 ! spinal cord development + +[Term] +id: GO:0021516 +name: dorsal spinal cord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11179871] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021510 ! spinal cord development + +[Term] +id: GO:0021517 +name: ventral spinal cord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021510 ! spinal cord development + +[Term] +id: GO:0021518 +name: spinal cord commissural neuron specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048665 ! neuron fate specification +relationship: part_of GO:0021528 ! commissural neuron differentiation in spinal cord + +[Term] +id: GO:0021519 +name: spinal cord association neuron specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048665 ! neuron fate specification +relationship: part_of GO:0021527 ! spinal cord association neuron differentiation + +[Term] +id: GO:0021520 +name: spinal cord motor neuron cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048665 ! neuron fate specification +relationship: part_of GO:0021522 ! spinal cord motor neuron differentiation + +[Term] +id: GO:0021521 +name: ventral spinal cord interneuron specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048665 ! neuron fate specification +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0060579 ! ventral spinal cord interneuron fate commitment + +[Term] +id: GO:0021522 +name: spinal cord motor neuron differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021517 ! ventral spinal cord development + +[Term] +id: GO:0021523 +name: somatic motor neuron differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021522 ! spinal cord motor neuron differentiation + +[Term] +id: GO:0021524 +name: visceral motor neuron differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021522 ! spinal cord motor neuron differentiation + +[Term] +id: GO:0021525 +name: lateral motor column neuron differentiation +namespace: biological_process +def: "The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021522 ! spinal cord motor neuron differentiation +relationship: part_of GO:0021523 ! somatic motor neuron differentiation + +[Term] +id: GO:0021526 +name: medial motor column neuron differentiation +namespace: biological_process +def: "The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0030182 ! neuron differentiation +relationship: part_of GO:0021523 ! somatic motor neuron differentiation + +[Term] +id: GO:0021527 +name: spinal cord association neuron differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "spinal cord dorsal interneuron differentiation" EXACT [GOC:dph] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021516 ! dorsal spinal cord development + +[Term] +id: GO:0021528 +name: commissural neuron differentiation in spinal cord +namespace: biological_process +def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0021953 ! central nervous system neuron differentiation + +[Term] +id: GO:0021529 +name: spinal cord oligodendrocyte cell differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0021530 +name: spinal cord oligodendrocyte cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021778 ! oligodendrocyte cell fate specification +relationship: part_of GO:0021529 ! spinal cord oligodendrocyte cell differentiation + +[Term] +id: GO:0021531 +name: spinal cord radial glial cell differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16185248] +synonym: "radial glial cell differentiation in spinal cord" EXACT [] +is_a: GO:0021515 ! cell differentiation in spinal cord +is_a: GO:0060019 ! radial glial cell differentiation + +[Term] +id: GO:0021532 +name: neural tube patterning +namespace: biological_process +def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0021915 ! neural tube development + +[Term] +id: GO:0021533 +name: cell differentiation in hindbrain +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021534 +name: cell proliferation in hindbrain +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0061351 ! neural precursor cell proliferation +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021535 +name: cell migration in hindbrain +namespace: biological_process +def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021536 +name: diencephalon development +namespace: biological_process +def: "The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021537 +name: telencephalon development +namespace: biological_process +def: "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cerebrum development" EXACT [GOC:sl, PMID:22331407] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021538 +name: epithalamus development +namespace: biological_process +def: "The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021536 ! diencephalon development + +[Term] +id: GO:0021539 +name: subthalamus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "ventral thalamus development" RELATED [GOC:cls] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021536 ! diencephalon development + +[Term] +id: GO:0021540 +name: corpus callosum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis +relationship: part_of GO:0022038 ! corpus callosum development + +[Term] +id: GO:0021541 +name: ammon gyrus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "Ammon's horn development" RELATED [GOC:cls] +synonym: "cornu ammonis development" RELATED [GOC:cls] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021766 ! hippocampus development + +[Term] +id: GO:0021542 +name: dentate gyrus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021766 ! hippocampus development + +[Term] +id: GO:0021543 +name: pallium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0021544 +name: subpallium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0021545 +name: cranial nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0021675 ! nerve development + +[Term] +id: GO:0021546 +name: rhombomere development +namespace: biological_process +def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021547 +name: midbrain-hindbrain boundary initiation +namespace: biological_process +def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] +synonym: "isthmus biosynthesis" RELATED [GOC:cls] +synonym: "isthmus formation" RELATED [GOC:cls] +synonym: "MHB biosynthesis" EXACT [GOC:cls] +synonym: "MHB formation" EXACT [GOC:cls] +synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls] +synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls] +is_a: GO:0003002 ! regionalization +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization +relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development + +[Term] +id: GO:0021548 +name: pons development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0022037 ! metencephalon development + +[Term] +id: GO:0021549 +name: cerebellum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0022037 ! metencephalon development + +[Term] +id: GO:0021550 +name: medulla oblongata development +namespace: biological_process +def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "medulla development" RELATED [GOC:cls] +synonym: "myelencephalon development" RELATED [GOC:cls] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021551 +name: central nervous system morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0021552 +name: midbrain-hindbrain boundary structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] +synonym: "isthmus structural organization" RELATED [GOC:cls] +synonym: "MHB structural organization" EXACT [GOC:cls] +synonym: "midbrain-hindbrain boundary structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021555 ! midbrain-hindbrain boundary morphogenesis + +[Term] +id: GO:0021553 +name: olfactory nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN 1 development" RELATED [GOC:cls] +synonym: "cranial nerve 1 development" EXACT [GOC:cls] +synonym: "cranial nerve I development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021554 +name: optic nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN II development" RELATED [GOC:cls] +synonym: "cranial nerve 2 development" EXACT [GOC:cls] +synonym: "cranial nerve II development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021555 +name: midbrain-hindbrain boundary morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] +synonym: "isthmus morphogenesis" EXACT [GOC:cls] +synonym: "MHB morphogenesis" EXACT [GOC:cls] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development + +[Term] +id: GO:0021556 +name: central nervous system formation +namespace: biological_process +def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021551 ! central nervous system morphogenesis + +[Term] +id: GO:0021557 +name: oculomotor nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN III development" RELATED [GOC:cls] +synonym: "cranial nerve 3 development" EXACT [GOC:cls] +synonym: "cranial nerve III development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development +relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development + +[Term] +id: GO:0021558 +name: trochlear nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IV development" RELATED [GOC:cls] +synonym: "cranial nerve 4 development" EXACT [GOC:cls] +synonym: "cranial nerve IV development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021559 +name: trigeminal nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN V development" RELATED [GOC:cls] +synonym: "cranial nerve 5 development" EXACT [GOC:cls] +synonym: "cranial nerve V development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021560 +name: abducens nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VI development" RELATED [GOC:cls] +synonym: "cranial nerve 6 development" EXACT [GOC:cls] +synonym: "cranial nerve VI development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021561 +name: facial nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII development" RELATED [GOC:cls] +synonym: "cranial nerve 7 development" EXACT [GOC:cls] +synonym: "cranial nerve VII development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development +relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development + +[Term] +id: GO:0021562 +name: vestibulocochlear nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "acoustic nerve development" EXACT [PMID:11533729] +synonym: "CN VIII development" EXACT [GOC:cls] +synonym: "cranial nerve 8 development" EXACT [GOC:cls] +synonym: "cranial nerve VIII development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021563 +name: glossopharyngeal nerve development +namespace: biological_process +def: "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IX development" RELATED [GOC:cls] +synonym: "cranial nerve 9 development" EXACT [GOC:cls] +synonym: "cranial nerve IX development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021564 +name: vagus nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN X development" RELATED [GOC:cls] +synonym: "cranial nerve 10 development" RELATED [GOC:cls] +synonym: "cranial nerve X development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development +relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development + +[Term] +id: GO:0021565 +name: accessory nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XI development" RELATED [GOC:cls] +synonym: "cranial nerve 11 development" RELATED [GOC:cls] +synonym: "cranial nerve XI development" EXACT [GOC:cls] +synonym: "spinal accessory nerve development" EXACT [PMID:11533729] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021566 +name: hypoglossal nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XII development" RELATED [GOC:cls] +synonym: "cranial nerve 12 development" RELATED [GOC:cls] +synonym: "cranial nerve XII development" EXACT [GOC:cls] +is_a: GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021567 +name: rhombomere 1 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021568 +name: rhombomere 2 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021569 +name: rhombomere 3 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021570 +name: rhombomere 4 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021571 +name: rhombomere 5 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021572 +name: rhombomere 6 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021573 +name: rhombomere 7 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021574 +name: rhombomere 8 development +namespace: biological_process +def: "The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021546 ! rhombomere development + +[Term] +id: GO:0021575 +name: hindbrain morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "rhombencephalon morphogenesis" RELATED [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021576 +name: hindbrain formation +namespace: biological_process +def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021575 ! hindbrain morphogenesis + +[Term] +id: GO:0021577 +name: hindbrain structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "hindbrain structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021575 ! hindbrain morphogenesis + +[Term] +id: GO:0021578 +name: hindbrain maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021626 ! central nervous system maturation +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021579 +name: medulla oblongata morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "medulla morphogenesis" RELATED [] +synonym: "myelencephalon morphogenesis" RELATED [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021550 ! medulla oblongata development +relationship: part_of GO:0021575 ! hindbrain morphogenesis + +[Term] +id: GO:0021580 +name: medulla oblongata formation +namespace: biological_process +def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "medulla biosynthesis" RELATED [] +synonym: "medulla formation" RELATED [] +synonym: "myelencephalon biosynthesis" RELATED [] +synonym: "myelencephalon formation" RELATED [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021576 ! hindbrain formation +relationship: part_of GO:0021579 ! medulla oblongata morphogenesis + +[Term] +id: GO:0021581 +name: medulla oblongata structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "medulla oblongata structural organisation" EXACT [GOC:mah] +synonym: "medulla structural maturation" RELATED [] +synonym: "myelencephalon structural maturation" RELATED [] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021577 ! hindbrain structural organization +relationship: part_of GO:0021579 ! medulla oblongata morphogenesis + +[Term] +id: GO:0021582 +name: medulla oblongata maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "medulla maturation" RELATED [] +synonym: "myelencephalon maturation" RELATED [] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021550 ! medulla oblongata development +relationship: part_of GO:0021578 ! hindbrain maturation + +[Term] +id: GO:0021583 +name: pons morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021548 ! pons development +relationship: part_of GO:0021575 ! hindbrain morphogenesis + +[Term] +id: GO:0021584 +name: pons formation +namespace: biological_process +def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021576 ! hindbrain formation +relationship: part_of GO:0021583 ! pons morphogenesis + +[Term] +id: GO:0021585 +name: pons structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "pons structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021577 ! hindbrain structural organization +relationship: part_of GO:0021583 ! pons morphogenesis + +[Term] +id: GO:0021586 +name: pons maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021548 ! pons development +relationship: part_of GO:0021578 ! hindbrain maturation + +[Term] +id: GO:0021587 +name: cerebellum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021549 ! cerebellum development +relationship: part_of GO:0021575 ! hindbrain morphogenesis + +[Term] +id: GO:0021588 +name: cerebellum formation +namespace: biological_process +def: "The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021576 ! hindbrain formation +relationship: part_of GO:0021587 ! cerebellum morphogenesis + +[Term] +id: GO:0021589 +name: cerebellum structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cerebellum structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021577 ! hindbrain structural organization +relationship: part_of GO:0021587 ! cerebellum morphogenesis + +[Term] +id: GO:0021590 +name: cerebellum maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021549 ! cerebellum development +relationship: part_of GO:0021578 ! hindbrain maturation + +[Term] +id: GO:0021591 +name: ventricular system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048731 ! system development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0021592 +name: fourth ventricle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021591 ! ventricular system development +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0021593 +name: rhombomere morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021546 ! rhombomere development + +[Term] +id: GO:0021594 +name: rhombomere formation +namespace: biological_process +def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021593 ! rhombomere morphogenesis + +[Term] +id: GO:0021595 +name: rhombomere structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "rhombomere structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021593 ! rhombomere morphogenesis + +[Term] +id: GO:0021597 +name: central nervous system structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] +synonym: "central nervous system structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021551 ! central nervous system morphogenesis + +[Term] +id: GO:0021598 +name: abducens nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VI development" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021560 ! abducens nerve development + +[Term] +id: GO:0021599 +name: abducens nerve formation +namespace: biological_process +def: "The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VI biosynthesis" RELATED [] +synonym: "CN VI formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021598 ! abducens nerve morphogenesis + +[Term] +id: GO:0021600 +name: abducens nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "abducens nerve structural organisation" EXACT [GOC:mah] +synonym: "CN VI structural organization" RELATED [] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021598 ! abducens nerve morphogenesis + +[Term] +id: GO:0021601 +name: abducens nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VI maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021560 ! abducens nerve development + +[Term] +id: GO:0021602 +name: cranial nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021603 +name: cranial nerve formation +namespace: biological_process +def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021602 ! cranial nerve morphogenesis + +[Term] +id: GO:0021604 +name: cranial nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cranial nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021602 ! cranial nerve morphogenesis + +[Term] +id: GO:0021605 +name: cranial nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0021682 ! nerve maturation +relationship: part_of GO:0021545 ! cranial nerve development + +[Term] +id: GO:0021606 +name: accessory nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XI maturation" RELATED [] +synonym: "spinal accessory nerve maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021565 ! accessory nerve development + +[Term] +id: GO:0021607 +name: accessory nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XI morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021565 ! accessory nerve development + +[Term] +id: GO:0021608 +name: accessory nerve formation +namespace: biological_process +def: "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XI biosynthesis" RELATED [] +synonym: "CN XI formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021607 ! accessory nerve morphogenesis + +[Term] +id: GO:0021609 +name: accessory nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "accessory nerve structural organisation" EXACT [GOC:mah] +synonym: "CN XI structural organization" RELATED [] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021607 ! accessory nerve morphogenesis + +[Term] +id: GO:0021610 +name: facial nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021561 ! facial nerve development + +[Term] +id: GO:0021611 +name: facial nerve formation +namespace: biological_process +def: "The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII biosynthesis" RELATED [] +synonym: "CN VII formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021610 ! facial nerve morphogenesis + +[Term] +id: GO:0021612 +name: facial nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII structural organization" RELATED [] +synonym: "facial nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021610 ! facial nerve morphogenesis + +[Term] +id: GO:0021613 +name: facial nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021561 ! facial nerve development + +[Term] +id: GO:0021614 +name: glossopharyngeal nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IX maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021563 ! glossopharyngeal nerve development + +[Term] +id: GO:0021615 +name: glossopharyngeal nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IX morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021563 ! glossopharyngeal nerve development + +[Term] +id: GO:0021616 +name: glossopharyngeal nerve formation +namespace: biological_process +def: "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IX biosynthesis" RELATED [] +synonym: "CN IX formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021615 ! glossopharyngeal nerve morphogenesis + +[Term] +id: GO:0021617 +name: glossopharyngeal nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IX structural organization" RELATED [] +synonym: "glossopharyngeal nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021615 ! glossopharyngeal nerve morphogenesis + +[Term] +id: GO:0021618 +name: hypoglossal nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XII morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021566 ! hypoglossal nerve development + +[Term] +id: GO:0021619 +name: hypoglossal nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XII maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021566 ! hypoglossal nerve development + +[Term] +id: GO:0021620 +name: hypoglossal nerve formation +namespace: biological_process +def: "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XII biosynthesis" RELATED [] +synonym: "CN XII formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021618 ! hypoglossal nerve morphogenesis + +[Term] +id: GO:0021621 +name: hypoglossal nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN XII structural organization" RELATED [] +synonym: "hypoglossal nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021618 ! hypoglossal nerve morphogenesis + +[Term] +id: GO:0021622 +name: oculomotor nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN III morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021557 ! oculomotor nerve development + +[Term] +id: GO:0021623 +name: oculomotor nerve formation +namespace: biological_process +def: "The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN III biosynthesis" RELATED [] +synonym: "CN III formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021622 ! oculomotor nerve morphogenesis + +[Term] +id: GO:0021624 +name: oculomotor nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN III structural organization" RELATED [] +synonym: "oculomotor nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021622 ! oculomotor nerve morphogenesis + +[Term] +id: GO:0021625 +name: oculomotor nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN III maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021557 ! oculomotor nerve development + +[Term] +id: GO:0021626 +name: central nervous system maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0021627 +name: olfactory nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN I morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021553 ! olfactory nerve development + +[Term] +id: GO:0021628 +name: olfactory nerve formation +namespace: biological_process +def: "The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN I biosynthesis" RELATED [] +synonym: "CN I formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021627 ! olfactory nerve morphogenesis + +[Term] +id: GO:0021629 +name: olfactory nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN I structural organization" RELATED [] +synonym: "olfactory nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021627 ! olfactory nerve morphogenesis + +[Term] +id: GO:0021630 +name: olfactory nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "CN I maturation" EXACT [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021553 ! olfactory nerve development + +[Term] +id: GO:0021631 +name: optic nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN II morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021554 ! optic nerve development + +[Term] +id: GO:0021632 +name: optic nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN II maturation" EXACT [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021554 ! optic nerve development + +[Term] +id: GO:0021633 +name: optic nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN II structural organization" RELATED [] +synonym: "optic nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021631 ! optic nerve morphogenesis + +[Term] +id: GO:0021634 +name: optic nerve formation +namespace: biological_process +def: "The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN II biosynthesis" RELATED [] +synonym: "CN II formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021631 ! optic nerve morphogenesis + +[Term] +id: GO:0021635 +name: trigeminal nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN V maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021559 ! trigeminal nerve development + +[Term] +id: GO:0021636 +name: trigeminal nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN V morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021559 ! trigeminal nerve development + +[Term] +id: GO:0021637 +name: trigeminal nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN V structural organization" RELATED [] +synonym: "trigeminal nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis + +[Term] +id: GO:0021638 +name: trigeminal nerve formation +namespace: biological_process +def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN V biosynthesis" RELATED [] +synonym: "CN V formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis + +[Term] +id: GO:0021639 +name: trochlear nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CH IV morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021558 ! trochlear nerve development + +[Term] +id: GO:0021640 +name: trochlear nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IV maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021558 ! trochlear nerve development + +[Term] +id: GO:0021641 +name: trochlear nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IV structural organization" RELATED [] +synonym: "trochlear nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021639 ! trochlear nerve morphogenesis + +[Term] +id: GO:0021642 +name: trochlear nerve formation +namespace: biological_process +def: "The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN IV biosynthesis" RELATED [] +synonym: "CN IV formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021639 ! trochlear nerve morphogenesis + +[Term] +id: GO:0021643 +name: vagus nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN X maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021564 ! vagus nerve development + +[Term] +id: GO:0021644 +name: vagus nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN X morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021564 ! vagus nerve development + +[Term] +id: GO:0021645 +name: vagus nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN X structural organization" RELATED [] +synonym: "vagus nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021644 ! vagus nerve morphogenesis + +[Term] +id: GO:0021646 +name: vagus nerve formation +namespace: biological_process +def: "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN X biosynthesis" RELATED [] +synonym: "CN X formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021644 ! vagus nerve morphogenesis + +[Term] +id: GO:0021647 +name: vestibulocochlear nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "auditory nerve maturation" RELATED [] +synonym: "CN VIII maturation" RELATED [] +is_a: GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0021562 ! vestibulocochlear nerve development + +[Term] +id: GO:0021648 +name: vestibulocochlear nerve morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VIII morphogenesis" RELATED [] +is_a: GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0021562 ! vestibulocochlear nerve development + +[Term] +id: GO:0021649 +name: vestibulocochlear nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII structural organization" RELATED [] +synonym: "vestibulocochlear nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0021648 ! vestibulocochlear nerve morphogenesis + +[Term] +id: GO:0021650 +name: vestibulocochlear nerve formation +namespace: biological_process +def: "The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "CN VII formation" RELATED [] +is_a: GO:0021603 ! cranial nerve formation +relationship: part_of GO:0021648 ! vestibulocochlear nerve morphogenesis + +[Term] +id: GO:0021651 +name: rhombomere 1 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021567 ! rhombomere 1 development + +[Term] +id: GO:0021652 +name: rhombomere 1 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021651 ! rhombomere 1 morphogenesis + +[Term] +id: GO:0021653 +name: rhombomere 1 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 1 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021651 ! rhombomere 1 morphogenesis + +[Term] +id: GO:0021654 +name: rhombomere boundary formation +namespace: biological_process +def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0021594 ! rhombomere formation + +[Term] +id: GO:0021655 +name: rhombomere 2 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021568 ! rhombomere 2 development + +[Term] +id: GO:0021656 +name: rhombomere 2 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 2 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021655 ! rhombomere 2 morphogenesis + +[Term] +id: GO:0021657 +name: rhombomere 2 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021655 ! rhombomere 2 morphogenesis + +[Term] +id: GO:0021658 +name: rhombomere 3 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021569 ! rhombomere 3 development + +[Term] +id: GO:0021659 +name: rhombomere 3 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 3 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021658 ! rhombomere 3 morphogenesis + +[Term] +id: GO:0021660 +name: rhombomere 3 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021658 ! rhombomere 3 morphogenesis + +[Term] +id: GO:0021661 +name: rhombomere 4 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021570 ! rhombomere 4 development + +[Term] +id: GO:0021662 +name: rhombomere 4 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 4 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021661 ! rhombomere 4 morphogenesis + +[Term] +id: GO:0021663 +name: rhombomere 4 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021661 ! rhombomere 4 morphogenesis + +[Term] +id: GO:0021664 +name: rhombomere 5 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021571 ! rhombomere 5 development + +[Term] +id: GO:0021665 +name: rhombomere 5 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 5 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021664 ! rhombomere 5 morphogenesis + +[Term] +id: GO:0021666 +name: rhombomere 5 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021664 ! rhombomere 5 morphogenesis + +[Term] +id: GO:0021667 +name: rhombomere 6 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021572 ! rhombomere 6 development + +[Term] +id: GO:0021668 +name: rhombomere 6 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 6 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021667 ! rhombomere 6 morphogenesis + +[Term] +id: GO:0021669 +name: rhombomere 6 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021667 ! rhombomere 6 morphogenesis + +[Term] +id: GO:0021670 +name: lateral ventricle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021537 ! telencephalon development +relationship: part_of GO:0021591 ! ventricular system development + +[Term] +id: GO:0021671 +name: rhombomere 7 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021573 ! rhombomere 7 development + +[Term] +id: GO:0021672 +name: rhombomere 7 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 7 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021671 ! rhombomere 7 morphogenesis + +[Term] +id: GO:0021673 +name: rhombomere 7 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021671 ! rhombomere 7 morphogenesis + +[Term] +id: GO:0021674 +name: rhombomere 8 morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021574 ! rhombomere 8 development + +[Term] +id: GO:0021675 +name: nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0021676 +name: rhombomere 8 structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rhombomere 8 structural organisation" EXACT [GOC:mah] +is_a: GO:0021595 ! rhombomere structural organization +relationship: part_of GO:0021674 ! rhombomere 8 morphogenesis + +[Term] +id: GO:0021677 +name: rhombomere 8 formation +namespace: biological_process +def: "The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021594 ! rhombomere formation +relationship: part_of GO:0021674 ! rhombomere 8 morphogenesis + +[Term] +id: GO:0021678 +name: third ventricle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021591 ! ventricular system development + +[Term] +id: GO:0021679 +name: cerebellar molecular layer development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021695 ! cerebellar cortex development + +[Term] +id: GO:0021680 +name: cerebellar Purkinje cell layer development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021695 ! cerebellar cortex development + +[Term] +id: GO:0021681 +name: cerebellar granular layer development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021695 ! cerebellar cortex development + +[Term] +id: GO:0021682 +name: nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021675 ! nerve development + +[Term] +id: GO:0021683 +name: cerebellar granular layer morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021681 ! cerebellar granular layer development +relationship: part_of GO:0021696 ! cerebellar cortex morphogenesis + +[Term] +id: GO:0021684 +name: cerebellar granular layer formation +namespace: biological_process +def: "The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021683 ! cerebellar granular layer morphogenesis +relationship: part_of GO:0021697 ! cerebellar cortex formation + +[Term] +id: GO:0021685 +name: cerebellar granular layer structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cerebellar granular layer structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021683 ! cerebellar granular layer morphogenesis +relationship: part_of GO:0021698 ! cerebellar cortex structural organization + +[Term] +id: GO:0021686 +name: cerebellar granular layer maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021681 ! cerebellar granular layer development +relationship: part_of GO:0021699 ! cerebellar cortex maturation + +[Term] +id: GO:0021687 +name: cerebellar molecular layer morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021679 ! cerebellar molecular layer development +relationship: part_of GO:0021696 ! cerebellar cortex morphogenesis + +[Term] +id: GO:0021688 +name: cerebellar molecular layer formation +namespace: biological_process +def: "The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021687 ! cerebellar molecular layer morphogenesis +relationship: part_of GO:0021697 ! cerebellar cortex formation + +[Term] +id: GO:0021689 +name: cerebellar molecular layer structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cerebellar molecular layer structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021687 ! cerebellar molecular layer morphogenesis +relationship: part_of GO:0021698 ! cerebellar cortex structural organization + +[Term] +id: GO:0021690 +name: cerebellar molecular layer maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021679 ! cerebellar molecular layer development +relationship: part_of GO:0021699 ! cerebellar cortex maturation + +[Term] +id: GO:0021691 +name: cerebellar Purkinje cell layer maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021680 ! cerebellar Purkinje cell layer development +relationship: part_of GO:0021699 ! cerebellar cortex maturation + +[Term] +id: GO:0021692 +name: cerebellar Purkinje cell layer morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021680 ! cerebellar Purkinje cell layer development +relationship: part_of GO:0021696 ! cerebellar cortex morphogenesis + +[Term] +id: GO:0021693 +name: cerebellar Purkinje cell layer structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cerebellar Purkinje cell layer structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021692 ! cerebellar Purkinje cell layer morphogenesis +relationship: part_of GO:0021698 ! cerebellar cortex structural organization + +[Term] +id: GO:0021694 +name: cerebellar Purkinje cell layer formation +namespace: biological_process +def: "The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021692 ! cerebellar Purkinje cell layer morphogenesis +relationship: part_of GO:0021697 ! cerebellar cortex formation + +[Term] +id: GO:0021695 +name: cerebellar cortex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0021696 +name: cerebellar cortex morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021587 ! cerebellum morphogenesis +relationship: part_of GO:0021695 ! cerebellar cortex development + +[Term] +id: GO:0021697 +name: cerebellar cortex formation +namespace: biological_process +def: "The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021696 ! cerebellar cortex morphogenesis + +[Term] +id: GO:0021698 +name: cerebellar cortex structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "cerebellar cortex structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021696 ! cerebellar cortex morphogenesis + +[Term] +id: GO:0021699 +name: cerebellar cortex maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021590 ! cerebellum maturation +relationship: part_of GO:0021695 ! cerebellar cortex development + +[Term] +id: GO:0021700 +name: developmental maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +subset: goslim_chembl +subset: goslim_generic +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0021701 +name: cerebellar Golgi cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +is_a: GO:0097154 ! GABAergic neuron differentiation +relationship: part_of GO:0021684 ! cerebellar granular layer formation + +[Term] +id: GO:0021702 +name: cerebellar Purkinje cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021694 ! cerebellar Purkinje cell layer formation + +[Term] +id: GO:0021703 +name: locus ceruleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "locus caeruleus development" EXACT [] +synonym: "locus coeruleus development" EXACT [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021704 +name: locus ceruleus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021583 ! pons morphogenesis +relationship: part_of GO:0021703 ! locus ceruleus development + +[Term] +id: GO:0021705 +name: locus ceruleus formation +namespace: biological_process +def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021584 ! pons formation +relationship: part_of GO:0021704 ! locus ceruleus morphogenesis + +[Term] +id: GO:0021706 +name: locus ceruleus maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021586 ! pons maturation +relationship: part_of GO:0021703 ! locus ceruleus development + +[Term] +id: GO:0021707 +name: cerebellar granule cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021684 ! cerebellar granular layer formation + +[Term] +id: GO:0021708 +name: Lugaro cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +is_a: GO:0097154 ! GABAergic neuron differentiation +relationship: part_of GO:0021697 ! cerebellar cortex formation + +[Term] +id: GO:0021709 +name: cerebellar basket cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021688 ! cerebellar molecular layer formation + +[Term] +id: GO:0021710 +name: cerebellar stellate cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021688 ! cerebellar molecular layer formation + +[Term] +id: GO:0021711 +name: cerebellar unipolar brush cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021684 ! cerebellar granular layer formation + +[Term] +id: GO:0021712 +name: candelabrum cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021694 ! cerebellar Purkinje cell layer formation + +[Term] +id: GO:0021713 +name: inferior olivary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "inferior olive development" RELATED [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021714 +name: inferior olivary nucleus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "inferior olive morphogenesis" RELATED [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021579 ! medulla oblongata morphogenesis +relationship: part_of GO:0021713 ! inferior olivary nucleus development + +[Term] +id: GO:0021715 +name: inferior olivary nucleus formation +namespace: biological_process +def: "The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "inferior olive biosynthesis" RELATED [] +synonym: "inferior olive formation" RELATED [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021580 ! medulla oblongata formation +relationship: part_of GO:0021714 ! inferior olivary nucleus morphogenesis + +[Term] +id: GO:0021716 +name: inferior olivary nucleus structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "inferior olivary nucleus structural organisation" EXACT [GOC:mah] +synonym: "inferior olive structural organization" RELATED [] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021581 ! medulla oblongata structural organization +relationship: part_of GO:0021714 ! inferior olivary nucleus morphogenesis + +[Term] +id: GO:0021717 +name: inferior olivary nucleus maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "inferior olive maturation" RELATED [] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021582 ! medulla oblongata maturation +relationship: part_of GO:0021713 ! inferior olivary nucleus development + +[Term] +id: GO:0021718 +name: superior olivary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "superior olive development" RELATED [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021719 +name: superior olivary nucleus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "superior olive morphogenesis" RELATED [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021583 ! pons morphogenesis +relationship: part_of GO:0021718 ! superior olivary nucleus development + +[Term] +id: GO:0021720 +name: superior olivary nucleus formation +namespace: biological_process +def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021584 ! pons formation +relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis + +[Term] +id: GO:0021721 +name: superior olivary nucleus structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "superior olivary nucleus structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0021585 ! pons structural organization +relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis + +[Term] +id: GO:0021722 +name: superior olivary nucleus maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +synonym: "superior olive maturation" RELATED [] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021586 ! pons maturation +relationship: part_of GO:0021718 ! superior olivary nucleus development + +[Term] +id: GO:0021723 +name: medullary reticular formation development +namespace: biological_process +def: "The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid, http://www.brainspan.org, Wikipedia:Rhombencephalon] +synonym: "rhombencephalic reticular formation development" BROAD [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021724 +name: inferior raphe nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:curators, GOC:cvs, GOC:dgh, GOC:dph, GOC:jid, PMID:19003874, ZFA:0000366] +synonym: "inferior central nucleus development" BROAD [] +synonym: "posterior raphe nucleus development" BROAD [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021725 +name: superior raphe nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:curators, GOC:cvs, GOC:dgh, GOC:dph, GOC:jid, PMID:19003874, ZFA:0000440] +synonym: "anterior raphe nucleus development" BROAD [] +synonym: "superior central nucleus development" BROAD [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021726 +name: lateral reticular nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021727 +name: intermediate reticular formation development +namespace: biological_process +def: "The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +synonym: "intermediate reticular nucleus development" EXACT [http://www.brainspan.org] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021728 +name: inferior reticular formation development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021729 +name: superior reticular formation development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021723 ! medullary reticular formation development + +[Term] +id: GO:0021730 +name: trigeminal sensory nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +comment: Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord. +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0021731 +name: trigeminal motor nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021732 +name: midbrain-hindbrain boundary maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] +synonym: "isthmus maturation" RELATED [] +synonym: "MHB maturation" RELATED [] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development + +[Term] +id: GO:0021735 +name: dentate nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0021736 +name: globose nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0021737 +name: emboliform nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0021738 +name: fastigial nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0021739 +name: mesencephalic trigeminal nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021730 ! trigeminal sensory nucleus development + +[Term] +id: GO:0021740 +name: principal sensory nucleus of trigeminal nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +comment: Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions. +synonym: "pontine nucleus development" BROAD [GOC:dph] +is_a: GO:0021730 ! trigeminal sensory nucleus development + +[Term] +id: GO:0021741 +name: spinal trigeminal nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021730 ! trigeminal sensory nucleus development + +[Term] +id: GO:0021742 +name: abducens nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021743 +name: hypoglossal nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021744 +name: dorsal motor nucleus of vagus nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021745 +name: nucleus ambiguus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021746 +name: solitary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021747 +name: cochlear nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021748 +name: dorsal cochlear nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021747 ! cochlear nucleus development + +[Term] +id: GO:0021749 +name: ventral cochlear nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021747 ! cochlear nucleus development + +[Term] +id: GO:0021750 +name: vestibular nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid, PMID:16221589] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development +relationship: part_of GO:0021550 ! medulla oblongata development + +[Term] +id: GO:0021751 +name: salivary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021752 +name: inferior salivary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021751 ! salivary nucleus development + +[Term] +id: GO:0021753 +name: superior salivary nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021751 ! salivary nucleus development + +[Term] +id: GO:0021754 +name: facial nucleus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021548 ! pons development + +[Term] +id: GO:0021755 +name: eurydendroid cell differentiation +namespace: biological_process +def: "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15892096] +is_a: GO:0021533 ! cell differentiation in hindbrain +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021697 ! cerebellar cortex formation + +[Term] +id: GO:0021756 +name: striatum development +namespace: biological_process +def: "The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "neostriatum development" EXACT [] +synonym: "striate nucleus development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021544 ! subpallium development + +[Term] +id: GO:0021757 +name: caudate nucleus development +namespace: biological_process +def: "The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021756 ! striatum development + +[Term] +id: GO:0021758 +name: putamen development +namespace: biological_process +def: "The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021756 ! striatum development + +[Term] +id: GO:0021759 +name: globus pallidus development +namespace: biological_process +def: "The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "pallidum development" EXACT [PMID:16271465] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021536 ! diencephalon development + +[Term] +id: GO:0021761 +name: limbic system development +namespace: biological_process +def: "The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048731 ! system development +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021762 +name: substantia nigra development +namespace: biological_process +def: "The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343, ISBN:0878937420] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0030901 ! midbrain development + +[Term] +id: GO:0021763 +name: subthalamic nucleus development +namespace: biological_process +def: "The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "corpus luysi development" RELATED [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021539 ! subthalamus development + +[Term] +id: GO:0021764 +name: amygdala development +namespace: biological_process +def: "The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021765 +name: cingulate gyrus development +namespace: biological_process +def: "The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021766 +name: hippocampus development +namespace: biological_process +def: "The progression of the hippocampus over time from its initial formation until its mature state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420, UBERON:0002421] +synonym: "hippocampal formation development" EXACT [ABA:HPF] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021543 ! pallium development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021767 +name: mammillary body development +namespace: biological_process +def: "The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021536 ! diencephalon development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021768 +name: nucleus accumbens development +namespace: biological_process +def: "The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "accumbens nucleus development" EXACT [GOC:dgh] +synonym: "ventral striatum development" BROAD [] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021756 ! striatum development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021769 +name: orbitofrontal cortex development +namespace: biological_process +def: "The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021770 +name: parahippocampal gyrus development +namespace: biological_process +def: "The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "hippocampal gyrus development" EXACT [GOC:dgh] +xref: Wikipedia:parahippocampal_gyrus +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021771 +name: lateral geniculate nucleus development +namespace: biological_process +def: "The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "LGN development" EXACT [GOC:dgh] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021794 ! thalamus development + +[Term] +id: GO:0021772 +name: olfactory bulb development +namespace: biological_process +def: "The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021988 ! olfactory lobe development + +[Term] +id: GO:0021773 +name: striatal medium spiny neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +synonym: "medium-sized spiny neuron differentiation" EXACT [PMID:25804741] +synonym: "striatal MSN differentiation" EXACT [PMID:25804741] +is_a: GO:0021879 ! forebrain neuron differentiation +relationship: part_of GO:0021756 ! striatum development + +[Term] +id: GO:0021774 +name: retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:sdb_2009, GOC:tb, PMID:11262869] +synonym: "retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification" EXACT [] +is_a: GO:0060895 ! retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0021521 ! ventral spinal cord interneuron specification +relationship: part_of GO:0021521 ! ventral spinal cord interneuron specification + +[Term] +id: GO:0021775 +name: smoothened signaling pathway involved in ventral spinal cord interneuron specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "hedgehog signaling pathway involved in ventral spinal cord interneuron specification" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in ventral spinal cord interneuron specification" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway involved in ventral spinal cord interneuron specification" EXACT [] +is_a: GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0021521 ! ventral spinal cord interneuron specification +relationship: part_of GO:0021521 ! ventral spinal cord interneuron specification + +[Term] +id: GO:0021776 +name: smoothened signaling pathway involved in spinal cord motor neuron cell fate specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15936325] +synonym: "hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in spinal cord motor neuron cell fate specification" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway involved in spinal cord motor neuron cell fate specification" EXACT [] +is_a: GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0021520 ! spinal cord motor neuron cell fate specification +relationship: part_of GO:0021520 ! spinal cord motor neuron cell fate specification + +[Term] +id: GO:0021777 +name: obsolete BMP signaling pathway involved in spinal cord association neuron specification +namespace: biological_process +def: "OBSOLETE. A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12593981] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "BMP signalling pathway involved in spinal cord association neuron specification" EXACT [] +synonym: "bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [] +synonym: "bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [] +is_obsolete: true + +[Term] +id: GO:0021778 +name: oligodendrocyte cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021780 ! glial cell fate specification +relationship: part_of GO:0021779 ! oligodendrocyte cell fate commitment + +[Term] +id: GO:0021779 +name: oligodendrocyte cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021781 ! glial cell fate commitment +is_a: GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0021780 +name: glial cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0021781 ! glial cell fate commitment + +[Term] +id: GO:0021781 +name: glial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0021782 +name: glial cell development +namespace: biological_process +def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0021783 +name: preganglionic parasympathetic fiber development +namespace: biological_process +def: "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048731 ! system development +relationship: part_of GO:0007417 ! central nervous system development +relationship: part_of GO:0048486 ! parasympathetic nervous system development + +[Term] +id: GO:0021784 +name: postganglionic parasympathetic fiber development +namespace: biological_process +def: "The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048483 ! autonomic nervous system development +relationship: part_of GO:0007422 ! peripheral nervous system development +relationship: part_of GO:0048486 ! parasympathetic nervous system development + +[Term] +id: GO:0021785 +name: branchiomotor neuron axon guidance +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "BMN axon guidance" EXACT [PMID:14699587] +synonym: "branchial motor axon guidance" EXACT [PMID:14699587] +synonym: "special visceral motor neuron axon guidance" EXACT [PMID:14699587] +is_a: GO:0008045 ! motor neuron axon guidance + +[Term] +id: GO:0021786 +name: branchiomotor neuron axon guidance in neural tube +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +is_a: GO:0021785 ! branchiomotor neuron axon guidance + +[Term] +id: GO:0021787 +name: chemorepulsion of branchiomotor neuron axon in neural tube +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "negative chemotaxis of branchiomotor neuron axon in neural tube" EXACT [GOC:mah] +is_a: GO:0021786 ! branchiomotor neuron axon guidance in neural tube +is_a: GO:0021793 ! chemorepulsion of branchiomotor axon + +[Term] +id: GO:0021788 +name: chemoattraction of branchiomotor neuron axon in neural tube +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "positive chemotaxis of branchiomotor neuron axon in neural tube" EXACT [GOC:mah] +is_a: GO:0021786 ! branchiomotor neuron axon guidance in neural tube +is_a: GO:0021792 ! chemoattraction of branchiomotor axon + +[Term] +id: GO:0021789 +name: branchiomotor neuron axon guidance in branchial arch mesenchyme +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +is_a: GO:0021785 ! branchiomotor neuron axon guidance + +[Term] +id: GO:0021790 +name: chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "negative chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme" EXACT [GOC:mah] +is_a: GO:0021789 ! branchiomotor neuron axon guidance in branchial arch mesenchyme +is_a: GO:0021793 ! chemorepulsion of branchiomotor axon + +[Term] +id: GO:0021791 +name: chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "positive chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme" EXACT [GOC:mah] +is_a: GO:0021789 ! branchiomotor neuron axon guidance in branchial arch mesenchyme +is_a: GO:0021792 ! chemoattraction of branchiomotor axon + +[Term] +id: GO:0021792 +name: chemoattraction of branchiomotor axon +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "positive chemotaxis of branchiomotor axon" EXACT [GOC:mah] +is_a: GO:0061642 ! chemoattraction of axon +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0021785 ! branchiomotor neuron axon guidance +relationship: part_of GO:0021785 ! branchiomotor neuron axon guidance + +[Term] +id: GO:0021793 +name: chemorepulsion of branchiomotor axon +namespace: biological_process +def: "The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587] +synonym: "negative chemotaxis of branchiomotor axon" EXACT [GOC:mah] +is_a: GO:0061643 ! chemorepulsion of axon +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0021785 ! branchiomotor neuron axon guidance +relationship: part_of GO:0021785 ! branchiomotor neuron axon guidance + +[Term] +id: GO:0021794 +name: thalamus development +namespace: biological_process +def: "The process in which the thalamus changes over time, from its initial formation to its mature state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021536 ! diencephalon development + +[Term] +id: GO:0021795 +name: cerebral cortex cell migration +namespace: biological_process +def: "The orderly movement of cells from one site to another in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022029 ! telencephalon cell migration +relationship: part_of GO:0021987 ! cerebral cortex development + +[Term] +id: GO:0021796 +name: cerebral cortex regionalization +namespace: biological_process +def: "The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "cerebral cortex arealization" EXACT [] +synonym: "cerebral cortex pattern biosynthesis" EXACT [] +synonym: "cerebral cortex pattern formation" EXACT [] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0021978 ! telencephalon regionalization +relationship: part_of GO:0021987 ! cerebral cortex development + +[Term] +id: GO:0021797 +name: forebrain anterior/posterior pattern specification +namespace: biological_process +def: "The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "forebrain anterior-posterior pattern specification" EXACT [] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0021871 ! forebrain regionalization + +[Term] +id: GO:0021798 +name: forebrain dorsal/ventral pattern formation +namespace: biological_process +def: "The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "forebrain dorsal-ventral pattern formation" EXACT [GOC:mah] +synonym: "forebrain dorsoventral pattern formation" EXACT [GOC:mah] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0021871 ! forebrain regionalization + +[Term] +id: GO:0021799 +name: cerebral cortex radially oriented cell migration +namespace: biological_process +def: "The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021795 ! cerebral cortex cell migration + +[Term] +id: GO:0021800 +name: cerebral cortex tangential migration +namespace: biological_process +def: "The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021795 ! cerebral cortex cell migration + +[Term] +id: GO:0021801 +name: cerebral cortex radial glia guided migration +namespace: biological_process +def: "The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "glial-guided locomotion" RELATED [PMID:12626695] +is_a: GO:0021799 ! cerebral cortex radially oriented cell migration +is_a: GO:0022030 ! telencephalon glial cell migration + +[Term] +id: GO:0021802 +name: somal translocation +namespace: biological_process +def: "The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "perikaryal translocation of Morest" EXACT [PMID:12626695] +is_a: GO:0021799 ! cerebral cortex radially oriented cell migration + +[Term] +id: GO:0021803 +name: extension of leading cell process to pial surface +namespace: biological_process +def: "The extension of a long process to the pial surface as a cell leaves the ventricular zone." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: part_of GO:0021802 ! somal translocation + +[Term] +id: GO:0021804 +name: negative regulation of cell adhesion in ventricular zone +namespace: biological_process +def: "The process that results in the loss of attachments of a cell in the ventricular zone." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "down regulation of cell adhesion in ventricular zone" EXACT [] +synonym: "down-regulation of cell adhesion in ventricular zone" EXACT [] +synonym: "downregulation of cell adhesion in ventricular zone" EXACT [] +synonym: "inhibition of cell adhesion in ventricular zone" NARROW [] +is_a: GO:0007162 ! negative regulation of cell adhesion +relationship: part_of GO:0021802 ! somal translocation + +[Term] +id: GO:0021805 +name: cell movement involved in somal translocation +namespace: biological_process +def: "The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cell motility involved in somal translocation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0048870 ! cell motility +intersection_of: GO:0048870 ! cell motility +intersection_of: part_of GO:0021802 ! somal translocation +relationship: part_of GO:0021802 ! somal translocation + +[Term] +id: GO:0021806 +name: initiation of movement involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "initiation of movement involved in cerebral cortex glial-mediated radial migration" RELATED [GOC:dph] +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0001667 ! ameboidal-type cell migration +relationship: part_of GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021807 +name: motogenic signaling initiating cell movement in cerebral cortex +namespace: biological_process +def: "The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "motogenic signalling initiating cell movement in the cerebral cortex" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0023052 ! signaling +relationship: part_of GO:0021806 ! initiation of movement involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021808 +name: cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration +namespace: biological_process +def: "The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration" EXACT [] +is_a: GO:0019722 ! calcium-mediated signaling +relationship: part_of GO:0021806 ! initiation of movement involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021809 +name: neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "neurotrophic factor signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration" EXACT [] +is_a: GO:0021807 ! motogenic signaling initiating cell movement in cerebral cortex + +[Term] +id: GO:0021810 +name: neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "neurotransmitter signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration" EXACT [] +is_a: GO:0021807 ! motogenic signaling initiating cell movement in cerebral cortex + +[Term] +id: GO:0021811 +name: growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:mtg_cardio] +synonym: "growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration" EXACT [] +is_a: GO:0021807 ! motogenic signaling initiating cell movement in cerebral cortex + +[Term] +id: GO:0021812 +name: neuronal-glial interaction involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "neuronal-glial interaction involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0021801 ! cerebral cortex radial glia guided migration + +[Term] +id: GO:0021813 +name: cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0021812 ! neuronal-glial interaction involved in cerebral cortex radial glia guided migration +relationship: part_of GO:0021812 ! neuronal-glial interaction involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021814 +name: cell motility involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cell locomotion involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +synonym: "cell locomotion involved in cerebral cortex radial glia guided migration" RELATED [GOC:dph] +is_a: GO:0048870 ! cell motility +intersection_of: GO:0048870 ! cell motility +intersection_of: part_of GO:0021801 ! cerebral cortex radial glia guided migration +relationship: part_of GO:0021801 ! cerebral cortex radial glia guided migration + +[Term] +id: GO:0021815 +name: modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +is_a: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: part_of GO:0021801 ! cerebral cortex radial glia guided migration +relationship: part_of GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021816 +name: extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021815 ! modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +is_a: GO:0031269 ! pseudopodium assembly + +[Term] +id: GO:0021817 +name: nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:12626695] +synonym: "nucleokinesis involved in cell locomotion in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +synonym: "nucleokinesis involved in cell locomotion in cerebral cortex radial glia guided migration" RELATED [GOC:dph, GOC:tb] +is_a: GO:0030473 ! nuclear migration along microtubule +relationship: part_of GO:0021815 ! modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021818 +name: modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +is_a: GO:0030036 ! actin cytoskeleton organization +relationship: part_of GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration + +[Term] +id: GO:0021819 +name: layer formation in cerebral cortex +namespace: biological_process +def: "The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "cerebral cortex lamination" RELATED [PMID:12626695] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021801 ! cerebral cortex radial glia guided migration + +[Term] +id: GO:0021820 +name: extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration" EXACT [GOC:mah] +synonym: "organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +is_a: GO:0030198 ! extracellular matrix organization +relationship: part_of GO:0021819 ! layer formation in cerebral cortex + +[Term] +id: GO:0021821 +name: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination +namespace: biological_process +def: "The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "down regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] +synonym: "down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] +synonym: "downregulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] +synonym: "inhibition of cell-glial cell adhesion involved in cerebral cortex lamination" NARROW [] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +relationship: part_of GO:0021819 ! layer formation in cerebral cortex + +[Term] +id: GO:0021822 +name: negative regulation of cell motility involved in cerebral cortex radial glia guided migration +namespace: biological_process +def: "The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:12626695] +synonym: "down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] +synonym: "down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] +synonym: "downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] +synonym: "inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" NARROW [] +synonym: "negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] +synonym: "negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration" RELATED [GOC:dph, GOC:tb] +is_a: GO:1903976 ! negative regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration +relationship: negatively_regulates GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration +relationship: part_of GO:0021819 ! layer formation in cerebral cortex + +[Term] +id: GO:0021823 +name: cerebral cortex tangential migration using cell-cell interactions +namespace: biological_process +def: "The process in which neurons interact with each other to promote migration along a tangential plane." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "chain migration" RELATED [PMID:12626695] +is_a: GO:0021825 ! substrate-dependent cerebral cortex tangential migration + +[Term] +id: GO:0021824 +name: cerebral cortex tangential migration using cell-axon interactions +namespace: biological_process +def: "The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021825 ! substrate-dependent cerebral cortex tangential migration + +[Term] +id: GO:0021825 +name: substrate-dependent cerebral cortex tangential migration +namespace: biological_process +def: "The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0006929 ! substrate-dependent cell migration +is_a: GO:0021800 ! cerebral cortex tangential migration + +[Term] +id: GO:0021826 +name: substrate-independent telencephalic tangential migration +namespace: biological_process +def: "The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0022029 ! telencephalon cell migration + +[Term] +id: GO:0021827 +name: postnatal olfactory bulb interneuron migration +namespace: biological_process +def: "The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions +is_a: GO:0022028 ! tangential migration from the subventricular zone to the olfactory bulb +relationship: part_of GO:0021891 ! olfactory bulb interneuron development + +[Term] +id: GO:0021828 +name: gonadotrophin-releasing hormone neuronal migration to the hypothalamus +namespace: biological_process +alt_id: GO:0021857 +def: "The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "gonadotropin-releasing hormone neuronal migration to the hypothalamus" EXACT [GOC:dph] +is_a: GO:0001764 ! neuron migration +is_a: GO:0021856 ! hypothalamic tangential migration using cell-axon interactions +relationship: part_of GO:0021888 ! hypothalamus gonadotrophin-releasing hormone neuron development + +[Term] +id: GO:0021829 +name: oligodendrocyte cell migration from the subpallium to the cortex +namespace: biological_process +def: "The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021826 ! substrate-independent telencephalic tangential migration +is_a: GO:0022030 ! telencephalon glial cell migration + +[Term] +id: GO:0021830 +name: interneuron migration from the subpallium to the cortex +namespace: biological_process +def: "The directed movement of interneurons from the subpallium to the cortex during forebrain development." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021843 ! substrate-independent telencephalic tangential interneuron migration + +[Term] +id: GO:0021831 +name: embryonic olfactory bulb interneuron precursor migration +namespace: biological_process +def: "The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021843 ! substrate-independent telencephalic tangential interneuron migration +is_a: GO:0022028 ! tangential migration from the subventricular zone to the olfactory bulb +relationship: part_of GO:0021891 ! olfactory bulb interneuron development + +[Term] +id: GO:0021832 +name: cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions +namespace: biological_process +def: "The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions +relationship: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions + +[Term] +id: GO:0021833 +name: cell-matrix adhesion involved in tangential migration using cell-cell interactions +namespace: biological_process +def: "The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex." [GO_REF:0000021, GOC:ascb_2009, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:12626695] +is_a: GO:0031589 ! cell-substrate adhesion +relationship: part_of GO:0021823 ! cerebral cortex tangential migration using cell-cell interactions + +[Term] +id: GO:0021834 +name: chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration +namespace: biological_process +def: "The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "negative chemotaxis involved in embryonic olfactory bulb interneuron precursor migration" EXACT [GOC:mah] +is_a: GO:0050919 ! negative chemotaxis +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration +relationship: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration + +[Term] +id: GO:0021835 +name: chemoattraction involved in embryonic olfactory bulb interneuron precursor migration +namespace: biological_process +def: "The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration" EXACT [GOC:mah] +is_a: GO:0050918 ! positive chemotaxis +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration +relationship: part_of GO:0021831 ! embryonic olfactory bulb interneuron precursor migration + +[Term] +id: GO:0021836 +name: chemorepulsion involved in postnatal olfactory bulb interneuron migration +namespace: biological_process +def: "The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "negative chemotaxis involved in postnatal olfactory bulb interneuron migration" EXACT [GOC:mah] +is_a: GO:0050919 ! negative chemotaxis +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0021827 ! postnatal olfactory bulb interneuron migration +relationship: part_of GO:0021827 ! postnatal olfactory bulb interneuron migration + +[Term] +id: GO:0021837 +name: motogenic signaling involved in postnatal olfactory bulb interneuron migration +namespace: biological_process +def: "The signaling that results in the stimulation of cell movement in the rostral migratory stream." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "motogenic signalling involved in postnatal olfactory bulb interneuron migration" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0023052 ! signaling +relationship: part_of GO:0021827 ! postnatal olfactory bulb interneuron migration + +[Term] +id: GO:0021838 +name: motogenic signaling involved in interneuron migration from the subpallium to the cortex +namespace: biological_process +def: "The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "motogenic signalling involved in interneuron migration from the subpallium to the cortex" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0023052 ! signaling +relationship: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex + +[Term] +id: GO:0021839 +name: interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex +namespace: biological_process +def: "The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0031589 ! cell-substrate adhesion +relationship: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex + +[Term] +id: GO:0021840 +name: directional guidance of interneurons involved in migration from the subpallium to the cortex +namespace: biological_process +def: "The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0030334 ! regulation of cell migration +relationship: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex + +[Term] +id: GO:0021841 +name: chemoattraction involved in interneuron migration from the subpallium to the cortex +namespace: biological_process +def: "The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "positive chemotaxis involved in interneuron migration from the subpallium to the cortex" EXACT [GOC:mah] +is_a: GO:0050918 ! positive chemotaxis +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex +relationship: part_of GO:0021840 ! directional guidance of interneurons involved in migration from the subpallium to the cortex + +[Term] +id: GO:0021842 +name: chemorepulsion involved in interneuron migration from the subpallium to the cortex +namespace: biological_process +def: "The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "negative chemotaxis involved in interneuron migration from the subpallium to the cortex" EXACT [GOC:mah] +is_a: GO:0050919 ! negative chemotaxis +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0021830 ! interneuron migration from the subpallium to the cortex +relationship: part_of GO:0021840 ! directional guidance of interneurons involved in migration from the subpallium to the cortex + +[Term] +id: GO:0021843 +name: substrate-independent telencephalic tangential interneuron migration +namespace: biological_process +def: "The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021826 ! substrate-independent telencephalic tangential migration + +[Term] +id: GO:0021844 +name: interneuron sorting involved in substrate-independent cerebral cortex tangential migration +namespace: biological_process +def: "The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0042330 ! taxis +relationship: part_of GO:0021843 ! substrate-independent telencephalic tangential interneuron migration + +[Term] +id: GO:0021845 +name: neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration +namespace: biological_process +def: "The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0030334 ! regulation of cell migration +relationship: part_of GO:0021843 ! substrate-independent telencephalic tangential interneuron migration + +[Term] +id: GO:0021846 +name: cell proliferation in forebrain +namespace: biological_process +def: "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0061351 ! neural precursor cell proliferation +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021847 +name: ventricular zone neuroblast division +namespace: biological_process +def: "The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "neuroblast division in ventricular zone" EXACT [] +is_a: GO:0021869 ! forebrain ventricular zone progenitor cell division +is_a: GO:0021873 ! forebrain neuroblast division + +[Term] +id: GO:0021848 +name: neuroblast division in subpallium +namespace: biological_process +def: "The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "neuroblast division in the ventral telencephalon" EXACT [PMID:16226447] +is_a: GO:0055057 ! neuroblast division +relationship: part_of GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0021849 +name: neuroblast division in subventricular zone +namespace: biological_process +def: "The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0055057 ! neuroblast division +relationship: part_of GO:0021846 ! cell proliferation in forebrain + +[Term] +id: GO:0021850 +name: subpallium glioblast cell division +namespace: biological_process +def: "The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "glioblast cell division in subpallium" EXACT [] +synonym: "glioblast division in ventral telencephalon" EXACT [PMID:16226447] +is_a: GO:0048860 ! glioblast division +relationship: part_of GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0021851 +name: neuroblast division in dorsal lateral ganglionic eminence +namespace: biological_process +def: "The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021848 ! neuroblast division in subpallium + +[Term] +id: GO:0021852 +name: pyramidal neuron migration +namespace: biological_process +def: "The migration of pyramidal a neuron precursor from the ventricular zone to the correct layer of the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "projection neuron migration" RELATED [PMID:12626695] +is_a: GO:0001764 ! neuron migration +is_a: GO:0021801 ! cerebral cortex radial glia guided migration +relationship: part_of GO:0021860 ! pyramidal neuron development + +[Term] +id: GO:0021853 +name: cerebral cortex GABAergic interneuron migration +namespace: biological_process +def: "The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021830 ! interneuron migration from the subpallium to the cortex +is_a: GO:1904936 ! interneuron migration +relationship: part_of GO:0021894 ! cerebral cortex GABAergic interneuron development + +[Term] +id: GO:0021854 +name: hypothalamus development +namespace: biological_process +def: "The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021536 ! diencephalon development +relationship: part_of GO:0021761 ! limbic system development + +[Term] +id: GO:0021855 +name: hypothalamus cell migration +namespace: biological_process +def: "The directed movement of a cell into the hypothalamus region of the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0021854 ! hypothalamus development + +[Term] +id: GO:0021856 +name: hypothalamic tangential migration using cell-axon interactions +namespace: biological_process +def: "The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021855 ! hypothalamus cell migration + +[Term] +id: GO:0021858 +name: GABAergic neuron differentiation in basal ganglia +namespace: biological_process +def: "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0097154 ! GABAergic neuron differentiation + +[Term] +id: GO:0021859 +name: pyramidal neuron differentiation +namespace: biological_process +def: "The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "projection neuron differentiation" BROAD [PMID:16226447] +is_a: GO:0021953 ! central nervous system neuron differentiation + +[Term] +id: GO:0021860 +name: pyramidal neuron development +namespace: biological_process +def: "The progression of a pyramidal neuron from its initial formation to its mature state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "projection neuron development" BROAD [PMID:16226447] +is_a: GO:0021884 ! forebrain neuron development +relationship: part_of GO:0021859 ! pyramidal neuron differentiation + +[Term] +id: GO:0021861 +name: forebrain radial glial cell differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "radial glial cell differentiation in forebrain" EXACT [] +is_a: GO:0060019 ! radial glial cell differentiation +relationship: part_of GO:0021872 ! forebrain generation of neurons + +[Term] +id: GO:0021862 +name: early neuron differentiation in forebrain +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0021879 ! forebrain neuron differentiation + +[Term] +id: GO:0021863 +name: forebrain neuroblast differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "abventricular progenitor cell differentiation" EXACT [PMID:16226447] +synonym: "intermediate progenitor cell differentiation" EXACT [PMID:16226447] +synonym: "non-surface dividing progenitor cell differentiation" EXACT [PMID:16226447] +is_a: GO:0014016 ! neuroblast differentiation +relationship: part_of GO:0021872 ! forebrain generation of neurons + +[Term] +id: GO:0021864 +name: obsolete radial glial cell division in forebrain +namespace: biological_process +def: "OBSOLETE. The mitotic division of radial glial cells in the developing forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021865 +name: obsolete symmetric radial glial cell division in forebrain +namespace: biological_process +def: "OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021866 +name: obsolete asymmetric radial glial cell division in forebrain +namespace: biological_process +def: "OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021867 +name: obsolete neuron-producing asymmetric radial glial cell division in forebrain +namespace: biological_process +def: "OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021868 +name: obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain +namespace: biological_process +def: "OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021869 +name: forebrain ventricular zone progenitor cell division +namespace: biological_process +def: "The mitotic division of a basal progenitor giving rise to two neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0051301 ! cell division +relationship: part_of GO:0021846 ! cell proliferation in forebrain + +[Term] +id: GO:0021870 +name: Cajal-Retzius cell differentiation +namespace: biological_process +def: "The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021895 ! cerebral cortex neuron differentiation + +[Term] +id: GO:0021871 +name: forebrain regionalization +namespace: biological_process +def: "The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:16226447] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021872 +name: forebrain generation of neurons +namespace: biological_process +def: "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "generation of neurons in forebrain" EXACT [] +is_a: GO:0048699 ! generation of neurons +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021873 +name: forebrain neuroblast division +namespace: biological_process +def: "The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0055057 ! neuroblast division +relationship: part_of GO:0021872 ! forebrain generation of neurons + +[Term] +id: GO:0021874 +name: Wnt signaling pathway involved in forebrain neuroblast division +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "Wnt receptor signaling pathway involved in forebrain neuroblast division" EXACT [] +synonym: "Wnt receptor signalling pathway in forebrain neuroblast division" EXACT [] +synonym: "Wnt-activated signaling pathway involved in forebrain neuroblast division" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0021873 ! forebrain neuroblast division +relationship: part_of GO:0021873 ! forebrain neuroblast division + +[Term] +id: GO:0021875 +name: fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "fibroblast growth factor receptor signalling pathway in forebrain neuroblast division" EXACT [] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0021873 ! forebrain neuroblast division +relationship: part_of GO:0021873 ! forebrain neuroblast division + +[Term] +id: GO:0021876 +name: Notch signaling pathway involved in forebrain neuroblast division +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "Notch signalling pathway in forebrain neuroblast division" EXACT [] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0021873 ! forebrain neuroblast division +relationship: part_of GO:0021873 ! forebrain neuroblast division + +[Term] +id: GO:0021877 +name: forebrain neuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0021879 ! forebrain neuron differentiation + +[Term] +id: GO:0021878 +name: forebrain astrocyte fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0060018 ! astrocyte fate commitment +relationship: part_of GO:0021896 ! forebrain astrocyte differentiation + +[Term] +id: GO:0021879 +name: forebrain neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0021872 ! forebrain generation of neurons + +[Term] +id: GO:0021880 +name: Notch signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "Notch signalling pathway involved in forebrain neuron fate commitment" EXACT [] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0021881 +name: Wnt-activated signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "Wnt receptor signaling pathway involved in forebrain neuron fate commitment" EXACT [] +synonym: "Wnt receptor signalling pathway involved in forebrain neuron fate commitment" EXACT [] +synonym: "Wnt-activated signaling pathway involved in forebrain neuron fate commitment" RELATED [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0021882 +name: regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0021883 +name: cell cycle arrest of committed forebrain neuronal progenitor cell +namespace: biological_process +def: "The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:16226447] +is_a: GO:0007050 ! cell cycle arrest +is_a: GO:0007406 ! negative regulation of neuroblast proliferation +is_a: GO:0051782 ! negative regulation of cell division +is_a: GO:2000035 ! regulation of stem cell division +relationship: negatively_regulates GO:0021873 ! forebrain neuroblast division +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021884 +name: forebrain neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021954 ! central nervous system neuron development +relationship: part_of GO:0021879 ! forebrain neuron differentiation + +[Term] +id: GO:0021885 +name: forebrain cell migration +namespace: biological_process +def: "The orderly movement of a cell from one site to another at least one of which is located in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021886 +name: hypothalamus gonadotrophin-releasing hormone neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "hypothalamus gonadotropin-releasing hormone neuron differentiation" EXACT [GOC:dph] +is_a: GO:0021979 ! hypothalamus cell differentiation + +[Term] +id: GO:0021887 +name: hypothalamus gonadotrophin-releasing hormone neuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "hypothalamus gonadotropin-releasing hormone neuron fate commitment" RELATED [GOC:dph] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0021886 ! hypothalamus gonadotrophin-releasing hormone neuron differentiation + +[Term] +id: GO:0021888 +name: hypothalamus gonadotrophin-releasing hormone neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +synonym: "hypothalamus gonadotropin-releasing hormone neuron development" RELATED [GOC:dph] +is_a: GO:0021884 ! forebrain neuron development +relationship: part_of GO:0021886 ! hypothalamus gonadotrophin-releasing hormone neuron differentiation + +[Term] +id: GO:0021889 +name: olfactory bulb interneuron differentiation +namespace: biological_process +def: "The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021879 ! forebrain neuron differentiation +relationship: part_of GO:0021772 ! olfactory bulb development + +[Term] +id: GO:0021890 +name: olfactory bulb interneuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0021889 ! olfactory bulb interneuron differentiation + +[Term] +id: GO:0021891 +name: olfactory bulb interneuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021884 ! forebrain neuron development +relationship: part_of GO:0021889 ! olfactory bulb interneuron differentiation + +[Term] +id: GO:0021892 +name: cerebral cortex GABAergic interneuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021895 ! cerebral cortex neuron differentiation +is_a: GO:0097154 ! GABAergic neuron differentiation + +[Term] +id: GO:0021893 +name: cerebral cortex GABAergic interneuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0021892 ! cerebral cortex GABAergic interneuron differentiation + +[Term] +id: GO:0021894 +name: cerebral cortex GABAergic interneuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021954 ! central nervous system neuron development +relationship: part_of GO:0021892 ! cerebral cortex GABAergic interneuron differentiation + +[Term] +id: GO:0021895 +name: cerebral cortex neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021896 +name: forebrain astrocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0048708 ! astrocyte differentiation +relationship: part_of GO:0030900 ! forebrain development + +[Term] +id: GO:0021897 +name: forebrain astrocyte development +namespace: biological_process +def: "The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0014002 ! astrocyte development +relationship: part_of GO:0021896 ! forebrain astrocyte differentiation + +[Term] +id: GO:0021898 +name: commitment of multipotent stem cells to neuronal lineage in forebrain +namespace: biological_process +def: "The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] +is_a: GO:0021877 ! forebrain neuron fate commitment + +[Term] +id: GO:0021899 +name: fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +synonym: "fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment" EXACT [] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0021900 +name: ventricular zone cell fate commitment +namespace: biological_process +def: "The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain +relationship: part_of GO:0021863 ! forebrain neuroblast differentiation + +[Term] +id: GO:0021901 +name: early neuron fate commitment in forebrain +namespace: biological_process +def: "The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain +relationship: part_of GO:0021862 ! early neuron differentiation in forebrain + +[Term] +id: GO:0021902 +name: commitment of neuronal cell to specific neuron type in forebrain +namespace: biological_process +def: "The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] +is_a: GO:0021877 ! forebrain neuron fate commitment + +[Term] +id: GO:0021903 +name: rostrocaudal neural tube patterning +namespace: biological_process +def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "anterior-posterior neural tube patterning" RELATED [GOC:dph] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0021532 ! neural tube patterning + +[Term] +id: GO:0021904 +name: dorsal/ventral neural tube patterning +namespace: biological_process +def: "The process in which the neural tube is regionalized in the dorsoventral axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "dorsal-ventral neural tube patterning" EXACT [GOC:dph] +synonym: "dorsoventral neural tube patterning" EXACT [GOC:mah] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0021532 ! neural tube patterning + +[Term] +id: GO:0021905 +name: forebrain-midbrain boundary formation +namespace: biological_process +def: "The process whose specific outcome is the creation of the forebrain-midbrain boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning + +[Term] +id: GO:0021906 +name: hindbrain-spinal cord boundary formation +namespace: biological_process +def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning + +[Term] +id: GO:0021907 +name: fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning" EXACT [] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0021512 ! spinal cord anterior/posterior patterning +relationship: part_of GO:0021512 ! spinal cord anterior/posterior patterning + +[Term] +id: GO:0021908 +name: retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning" EXACT [] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0021512 ! spinal cord anterior/posterior patterning +relationship: part_of GO:0021512 ! spinal cord anterior/posterior patterning + +[Term] +id: GO:0021909 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0021910 +name: smoothened signaling pathway involved in ventral spinal cord patterning +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:11262869] +synonym: "hedgehog signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway in ventral spinal cord patterning" EXACT [] +is_a: GO:0007224 ! smoothened signaling pathway +relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning + +[Term] +id: GO:0021911 +name: retinoic acid metabolic process in spinal cord anterior-posterior patterning +namespace: biological_process +def: "The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "retinoic acid metabolism in spinal cord anterior-posterior patterning" EXACT [] +is_a: GO:0042573 ! retinoic acid metabolic process +relationship: part_of GO:0021512 ! spinal cord anterior/posterior patterning + +[Term] +id: GO:0021912 +name: regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +relationship: part_of GO:0021520 ! spinal cord motor neuron cell fate specification + +[Term] +id: GO:0021913 +name: regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0021521 ! ventral spinal cord interneuron specification +relationship: part_of GO:0021521 ! ventral spinal cord interneuron specification + +[Term] +id: GO:0021914 +name: negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:11262869] +synonym: "down regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] +synonym: "down-regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] +synonym: "downregulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] +synonym: "inhibition of smoothened signaling pathway in ventral spinal cord patterning" NARROW [] +synonym: "negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "negative regulation of hh signaling pathway involved in ventral spinal cord patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "negative regulation of smoothened signalling pathway in ventral spinal cord patterning" EXACT [] +is_a: GO:0045879 ! negative regulation of smoothened signaling pathway +is_a: GO:0051961 ! negative regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning +relationship: negatively_regulates GO:0021910 ! smoothened signaling pathway involved in ventral spinal cord patterning +relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning + +[Term] +id: GO:0021915 +name: neural tube development +namespace: biological_process +def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0035295 ! tube development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0007399 ! nervous system development +relationship: part_of GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0021916 +name: inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors +namespace: biological_process +def: "Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +synonym: "inductive cell-cell signalling between paraxial mesoderm and motor neuron precursors" EXACT [] +is_a: GO:0031129 ! inductive cell-cell signaling +relationship: part_of GO:0021917 ! somatic motor neuron fate commitment + +[Term] +id: GO:0021917 +name: somatic motor neuron fate commitment +namespace: biological_process +def: "The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0021523 ! somatic motor neuron differentiation + +[Term] +id: GO:0021918 +name: regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0021917 ! somatic motor neuron fate commitment +relationship: part_of GO:0021917 ! somatic motor neuron fate commitment + +[Term] +id: GO:0021919 +name: BMP signaling pathway involved in spinal cord dorsal/ventral patterning +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12593981] +synonym: "BMP signaling pathway in spinal cord dorsoventral patterning" EXACT [GOC:mah] +synonym: "BMP signaling pathway involved in spinal cord dorsal-ventral patterning" EXACT [GOC:mah] +synonym: "BMP signalling pathway involved in spinal cord dorsal-ventral patterning" EXACT [] +synonym: "bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning" EXACT [] +synonym: "bone morphogenetic protein signalling pathway involved in spinal cord dorsal-ventral patterning" EXACT [] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0021513 ! spinal cord dorsal/ventral patterning +relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning + +[Term] +id: GO:0021920 +name: regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12593981] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0021519 ! spinal cord association neuron specification +relationship: part_of GO:0021519 ! spinal cord association neuron specification + +[Term] +id: GO:0021921 +name: regulation of cell proliferation in dorsal spinal cord +namespace: biological_process +def: "The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010456 ! cell proliferation in dorsal spinal cord +relationship: part_of GO:0021516 ! dorsal spinal cord development +relationship: regulates GO:0010456 ! cell proliferation in dorsal spinal cord + +[Term] +id: GO:0021922 +name: Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12593981] +synonym: "Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord" EXACT [] +synonym: "Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord" EXACT [] +synonym: "Wnt-activated signaling pathway involved in regulation of cell proliferation in dorsal spinal cord" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0021921 ! regulation of cell proliferation in dorsal spinal cord +relationship: part_of GO:0021921 ! regulation of cell proliferation in dorsal spinal cord + +[Term] +id: GO:0021923 +name: cell proliferation in hindbrain ventricular zone +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12593981, PMID:15157725] +is_a: GO:0021534 ! cell proliferation in hindbrain + +[Term] +id: GO:0021924 +name: cell proliferation in external granule layer +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021534 ! cell proliferation in hindbrain + +[Term] +id: GO:0021925 +name: cerebellar Purkinje cell precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021923 ! cell proliferation in hindbrain ventricular zone + +[Term] +id: GO:0021926 +name: Golgi cell precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021923 ! cell proliferation in hindbrain ventricular zone + +[Term] +id: GO:0021927 +name: deep nuclear neuron precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021923 ! cell proliferation in hindbrain ventricular zone + +[Term] +id: GO:0021928 +name: basket cell precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021923 ! cell proliferation in hindbrain ventricular zone + +[Term] +id: GO:0021929 +name: stellate cell precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021923 ! cell proliferation in hindbrain ventricular zone + +[Term] +id: GO:0021930 +name: cerebellar granule cell precursor proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021924 ! cell proliferation in external granule layer + +[Term] +id: GO:0021931 +name: rostral hindbrain neuronal precursor cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021924 ! cell proliferation in external granule layer + +[Term] +id: GO:0021932 +name: hindbrain radial glia guided cell migration +namespace: biological_process +def: "The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021535 ! cell migration in hindbrain + +[Term] +id: GO:0021933 +name: radial glia guided migration of cerebellar granule cell +namespace: biological_process +def: "The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021932 ! hindbrain radial glia guided cell migration + +[Term] +id: GO:0021934 +name: hindbrain tangential cell migration +namespace: biological_process +def: "The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "hindbrain neurophilic migration" RELATED [PMID:15157725] +is_a: GO:0021535 ! cell migration in hindbrain + +[Term] +id: GO:0021935 +name: cerebellar granule cell precursor tangential migration +namespace: biological_process +def: "The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021934 ! hindbrain tangential cell migration + +[Term] +id: GO:0021936 +name: regulation of cerebellar granule cell precursor proliferation +namespace: biological_process +def: "The process that modulates the frequency, rate or extent of granule cell precursor proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0021930 ! cerebellar granule cell precursor proliferation +relationship: regulates GO:0021930 ! cerebellar granule cell precursor proliferation + +[Term] +id: GO:0021937 +name: cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +namespace: biological_process +def: "The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0021940 ! positive regulation of cerebellar granule cell precursor proliferation + +[Term] +id: GO:0021938 +name: smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:15157725] +synonym: "hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in regulation of granule cell precursor cell proliferation" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway in regulation of granule cell precursor cell proliferation" EXACT [] +is_a: GO:0007224 ! smoothened signaling pathway +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +relationship: part_of GO:0021937 ! cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation + +[Term] +id: GO:0021939 +name: extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation +namespace: biological_process +def: "The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation" EXACT [] +is_a: GO:0035426 ! extracellular matrix-cell signaling +relationship: part_of GO:0021941 ! negative regulation of cerebellar granule cell precursor proliferation + +[Term] +id: GO:0021940 +name: positive regulation of cerebellar granule cell precursor proliferation +namespace: biological_process +def: "The process that activates or increases the rate or extent of granule cell precursor proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "activation of granule cell precursor proliferation" NARROW [] +synonym: "stimulation of granule cell precursor proliferation" NARROW [] +synonym: "up regulation of granule cell precursor proliferation" EXACT [] +synonym: "up-regulation of granule cell precursor proliferation" EXACT [] +synonym: "upregulation of granule cell precursor proliferation" EXACT [] +is_a: GO:0021936 ! regulation of cerebellar granule cell precursor proliferation +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0021930 ! cerebellar granule cell precursor proliferation +relationship: positively_regulates GO:0021930 ! cerebellar granule cell precursor proliferation + +[Term] +id: GO:0021941 +name: negative regulation of cerebellar granule cell precursor proliferation +namespace: biological_process +def: "The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "down regulation of granule cell precursor proliferation" EXACT [] +synonym: "down-regulation of granule cell precursor proliferation" EXACT [] +synonym: "downregulation of granule cell precursor proliferation" EXACT [] +synonym: "inhibition of granule cell precursor proliferation" NARROW [] +is_a: GO:0021936 ! regulation of cerebellar granule cell precursor proliferation +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021930 ! cerebellar granule cell precursor proliferation +relationship: negatively_regulates GO:0021930 ! cerebellar granule cell precursor proliferation + +[Term] +id: GO:0021942 +name: radial glia guided migration of Purkinje cell +namespace: biological_process +def: "The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021932 ! hindbrain radial glia guided cell migration + +[Term] +id: GO:0021943 +name: formation of radial glial scaffolds +namespace: biological_process +def: "The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "Bergmann fiber biosynthesis" RELATED [PMID:15157725] +synonym: "Bergmann fiber formation" RELATED [PMID:15157725] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0021932 ! hindbrain radial glia guided cell migration + +[Term] +id: GO:0021944 +name: neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration +namespace: biological_process +def: "The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0021932 ! hindbrain radial glia guided cell migration + +[Term] +id: GO:0021945 +name: positive regulation of cerebellar granule cell migration by calcium +namespace: biological_process +def: "The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb, PMID:15157725] +synonym: "calcium-mediated activation of granule cell migration" NARROW [] +synonym: "calcium-mediated positive regulation of granule cell migration" EXACT [GOC:dph, GOC:tb] +synonym: "calcium-mediated stimulation of granule cell migration" NARROW [] +synonym: "calcium-mediated up regulation of granule cell migration" EXACT [] +synonym: "calcium-mediated up-regulation of granule cell migration" EXACT [] +synonym: "calcium-mediated upregulation of granule cell migration" EXACT [] +is_a: GO:0019722 ! calcium-mediated signaling +is_a: GO:0030335 ! positive regulation of cell migration +relationship: part_of GO:0021933 ! radial glia guided migration of cerebellar granule cell + +[Term] +id: GO:0021946 +name: deep nuclear neuron cell migration +namespace: biological_process +def: "The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021535 ! cell migration in hindbrain + +[Term] +id: GO:0021947 +name: outward migration of deep nuclear neurons +namespace: biological_process +def: "The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0001764 ! neuron migration +is_a: GO:0021535 ! cell migration in hindbrain +relationship: part_of GO:0021946 ! deep nuclear neuron cell migration + +[Term] +id: GO:0021948 +name: inward migration of deep nuclear neurons +namespace: biological_process +def: "The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0001764 ! neuron migration +is_a: GO:0021535 ! cell migration in hindbrain +relationship: part_of GO:0021946 ! deep nuclear neuron cell migration + +[Term] +id: GO:0021949 +name: brainstem precerebellar neuron precursor migration +namespace: biological_process +def: "The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +is_a: GO:0021934 ! hindbrain tangential cell migration + +[Term] +id: GO:0021950 +name: chemorepulsion involved in precerebellar neuron migration +namespace: biological_process +def: "The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "negative chemotaxis involved in precerebellar neuron migration" EXACT [GOC:mah] +is_a: GO:0050919 ! negative chemotaxis +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration +relationship: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration + +[Term] +id: GO:0021951 +name: chemoattraction involved in precerebellar neuron migration +namespace: biological_process +def: "The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725] +synonym: "positive chemotaxis involved in precerebellar neuron migration" EXACT [GOC:mah] +is_a: GO:0050918 ! positive chemotaxis +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration +relationship: part_of GO:0021949 ! brainstem precerebellar neuron precursor migration + +[Term] +id: GO:0021952 +name: central nervous system projection neuron axonogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "central nervous system axon tract development" NARROW [GOC:dph] +is_a: GO:0021955 ! central nervous system neuron axonogenesis + +[Term] +id: GO:0021953 +name: central nervous system neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0030182 ! neuron differentiation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0021954 +name: central nervous system neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0021953 ! central nervous system neuron differentiation + +[Term] +id: GO:0021955 +name: central nervous system neuron axonogenesis +namespace: biological_process +def: "Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0007409 ! axonogenesis +relationship: part_of GO:0021954 ! central nervous system neuron development + +[Term] +id: GO:0021956 +name: central nervous system interneuron axonogenesis +namespace: biological_process +def: "Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021955 ! central nervous system neuron axonogenesis + +[Term] +id: GO:0021957 +name: corticospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal tract axonogenesis" EXACT [GOC:dph, PMID:9878731] +synonym: "CST axonogenesis" EXACT [GOC:dph, PMID:9878731] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021958 +name: gracilis tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12867698] +synonym: "tract of Goll morphogenesis" EXACT [PMID:12867698] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021959 +name: cuneatus tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12867698] +synonym: "tract of Burdach morphogenesis" EXACT [PMID:12867698] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021960 +name: anterior commissure morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0021961 +name: posterior commissure morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021962 +name: vestibulospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021963 +name: spinothalamic tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "dorsolateral tract of Lissauer morphogenesis" EXACT [] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021964 +name: rubrospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021965 +name: spinal cord ventral commissure morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis +relationship: part_of GO:0021510 ! spinal cord development + +[Term] +id: GO:0021966 +name: corticospinal neuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021957 ! corticospinal tract morphogenesis + +[Term] +id: GO:0021967 +name: corticospinal neuron axon guidance through the cerebral cortex +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through the cerebral cortex" NARROW [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021968 +name: corticospinal neuron axon guidance through the internal capsule +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through the internal capsule" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021969 +name: corticospinal neuron axon guidance through the cerebral peduncle +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through the cerebral peduncle" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021970 +name: corticospinal neuron axon guidance through the basilar pons +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through the basilar pons" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021971 +name: corticospinal neuron axon guidance through the medullary pyramid +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through the medullary pyramid" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021972 +name: corticospinal neuron axon guidance through spinal cord +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +synonym: "corticospinal neuron axon pathfinding through spinal cord" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021973 +name: corticospinal neuron axon decussation +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731] +is_a: GO:0016199 ! axon midline choice point recognition +relationship: part_of GO:0021966 ! corticospinal neuron axon guidance + +[Term] +id: GO:0021974 +name: trigeminothalamic tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021975 +name: pons reticulospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021976 +name: medulla reticulospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021977 +name: tectospinal tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0021978 +name: telencephalon regionalization +namespace: biological_process +def: "The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mgi_curators] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0021537 ! telencephalon development +relationship: part_of GO:0021871 ! forebrain regionalization + +[Term] +id: GO:0021979 +name: hypothalamus cell differentiation +namespace: biological_process +def: "The differentiation of cells that will contribute to the structure and function of the hypothalamus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mgi_curators] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021854 ! hypothalamus development + +[Term] +id: GO:0021980 +name: subpallium cell migration +namespace: biological_process +def: "The orderly movement of cells from one site to another in the subpallium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022029 ! telencephalon cell migration +relationship: part_of GO:0021544 ! subpallium development + +[Term] +id: GO:0021981 +name: subpallium radially oriented migration +namespace: biological_process +def: "The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021980 ! subpallium cell migration + +[Term] +id: GO:0021982 +name: pineal gland development +namespace: biological_process +def: "The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "epiphysis development" EXACT [GOC:dph] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0021536 ! diencephalon development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0021983 +name: pituitary gland development +namespace: biological_process +def: "The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "hypophysis development" RELATED [GOC:dph] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0021536 ! diencephalon development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0021984 +name: adenohypophysis development +namespace: biological_process +def: "The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "adenophysis development" EXACT [] +synonym: "anterior pituitary development" EXACT [] +synonym: "anterior pituitary gland development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021983 ! pituitary gland development + +[Term] +id: GO:0021985 +name: neurohypophysis development +namespace: biological_process +def: "The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neurophysis development" EXACT [] +synonym: "posterior pituitary development" EXACT [] +synonym: "posterior pituitary gland development" EXACT [] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0021983 ! pituitary gland development + +[Term] +id: GO:0021986 +name: habenula development +namespace: biological_process +def: "The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:9780721601465] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021538 ! epithalamus development + +[Term] +id: GO:0021987 +name: cerebral cortex development +namespace: biological_process +def: "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "corticogenesis" NARROW [GOC:bf, PMID:25904839] +synonym: "neocortex development" RELATED [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021543 ! pallium development + +[Term] +id: GO:0021988 +name: olfactory lobe development +namespace: biological_process +def: "The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0021989 +name: olfactory cortex development +namespace: biological_process +def: "The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021988 ! olfactory lobe development + +[Term] +id: GO:0021990 +name: neural plate formation +namespace: biological_process +def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0001839 ! neural plate morphogenesis + +[Term] +id: GO:0021991 +name: neural plate thickening +namespace: biological_process +def: "The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586] +is_a: GO:0002011 ! morphogenesis of an epithelial sheet +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001839 ! neural plate morphogenesis + +[Term] +id: GO:0021992 +name: cell proliferation involved in neural plate elongation +namespace: biological_process +def: "The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15806586] +is_a: GO:0061351 ! neural precursor cell proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0014022 ! neural plate elongation +relationship: part_of GO:0014022 ! neural plate elongation + +[Term] +id: GO:0021993 +name: initiation of neural tube closure +namespace: biological_process +def: "The process in which closure points are established at multiple points and along the neural rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001843 ! neural tube closure + +[Term] +id: GO:0021994 +name: progression of neural tube closure +namespace: biological_process +def: "The process in which the neural folds are fused extending from the initial closure points." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0001843 ! neural tube closure + +[Term] +id: GO:0021995 +name: neuropore closure +namespace: biological_process +def: "The process of joining together the neural folds at either end of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0001843 ! neural tube closure + +[Term] +id: GO:0021996 +name: lamina terminalis formation +namespace: biological_process +def: "The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021506 ! anterior neuropore closure + +[Term] +id: GO:0021997 +name: neural plate axis specification +namespace: biological_process +def: "The pattern specification process in which the axes of the nervous system are established." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neural plate axis determination" RELATED [GOC:dph] +is_a: GO:0000578 ! embryonic axis specification +relationship: part_of GO:0001840 ! neural plate development +relationship: part_of GO:0060896 ! neural plate pattern specification + +[Term] +id: GO:0021998 +name: neural plate mediolateral regionalization +namespace: biological_process +def: "The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neural plate mediolateral pattern formation" RELATED [GOC:dph] +is_a: GO:0060897 ! neural plate regionalization + +[Term] +id: GO:0021999 +name: neural plate anterior/posterior regionalization +namespace: biological_process +def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neural plate anterior/posterior pattern formation" RELATED [GOC:dph] +is_a: GO:0009952 ! anterior/posterior pattern specification +is_a: GO:0060897 ! neural plate regionalization + +[Term] +id: GO:0022000 +name: forebrain induction by the anterior neural ridge +namespace: biological_process +def: "The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0031128 ! developmental induction +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization + +[Term] +id: GO:0022001 +name: negative regulation of anterior neural cell fate commitment of the neural plate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb] +synonym: "caudalization of neural plate" EXACT [] +synonym: "down regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "down-regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "downregulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "inhibition of anterior neural cell fate of the neural plate" NARROW [] +synonym: "negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] +synonym: "posteriorization" BROAD [] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0051961 ! negative regulation of nervous system development +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization + +[Term] +id: GO:0022002 +name: negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway +namespace: biological_process +def: "The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb] +synonym: "negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway" EXACT [] +synonym: "negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate" NARROW [] +synonym: "Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] +synonym: "Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [] +is_a: GO:0016055 ! Wnt signaling pathway +is_a: GO:0022001 ! negative regulation of anterior neural cell fate commitment of the neural plate + +[Term] +id: GO:0022003 +name: negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:tb] +synonym: "fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate" EXACT [] +synonym: "fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate" NARROW [] +synonym: "fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] +synonym: "fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [] +is_a: GO:0022001 ! negative regulation of anterior neural cell fate commitment of the neural plate +is_a: GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation + +[Term] +id: GO:0022004 +name: midbrain-hindbrain boundary maturation during brain development +namespace: biological_process +def: "A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0021732 ! midbrain-hindbrain boundary maturation + +[Term] +id: GO:0022005 +name: midbrain-hindbrain boundary maturation during neural plate development +namespace: biological_process +def: "A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] +synonym: "midbrain-hindbrain boundary maturation involved in neural plate development" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0021732 ! midbrain-hindbrain boundary maturation + +[Term] +id: GO:0022006 +name: zona limitans intrathalamica formation +namespace: biological_process +def: "The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11425897, PMID:16452095] +synonym: "zli biosynthesis" EXACT [] +synonym: "zli formation" EXACT [] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning + +[Term] +id: GO:0022007 +name: convergent extension involved in neural plate elongation +namespace: biological_process +def: "The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:13679871, PMID:15806586] +is_a: GO:0060027 ! convergent extension involved in gastrulation +is_a: GO:0060029 ! convergent extension involved in organogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0014022 ! neural plate elongation +relationship: part_of GO:0014022 ! neural plate elongation + +[Term] +id: GO:0022008 +name: neurogenesis +namespace: biological_process +def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +synonym: "nervous system cell generation" EXACT systematic_synonym [] +synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph] +xref: Wikipedia:Neurogenesis +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0022009 +name: central nervous system vasculogenesis +namespace: biological_process +def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0001570 ! vasculogenesis +relationship: part_of GO:0014045 ! establishment of endothelial blood-brain barrier + +[Term] +id: GO:0022010 +name: central nervous system myelination +namespace: biological_process +def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "myelination in central nervous system" EXACT [] +is_a: GO:0032291 ! axon ensheathment in central nervous system +is_a: GO:0042552 ! myelination +relationship: part_of GO:0014003 ! oligodendrocyte development + +[Term] +id: GO:0022011 +name: myelination in peripheral nervous system +namespace: biological_process +def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "peripheral nervous system myelination" EXACT [] +is_a: GO:0032292 ! peripheral nervous system axon ensheathment +is_a: GO:0042552 ! myelination +relationship: part_of GO:0014044 ! Schwann cell development + +[Term] +id: GO:0022012 +name: subpallium cell proliferation in forebrain +namespace: biological_process +def: "The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021846 ! cell proliferation in forebrain +relationship: part_of GO:0021544 ! subpallium development + +[Term] +id: GO:0022013 +name: pallium cell proliferation in forebrain +namespace: biological_process +def: "The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021846 ! cell proliferation in forebrain +relationship: part_of GO:0021543 ! pallium development + +[Term] +id: GO:0022014 +name: obsolete radial glial cell division in subpallium +namespace: biological_process +def: "OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0022015 +name: radial glial cell division in pallium +namespace: biological_process +def: "The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0051301 ! cell division +relationship: part_of GO:0022013 ! pallium cell proliferation in forebrain + +[Term] +id: GO:0022016 +name: pallium glioblast division +namespace: biological_process +def: "The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "glioblast cell division in pallium" EXACT [] +is_a: GO:0048860 ! glioblast division +relationship: part_of GO:0022013 ! pallium cell proliferation in forebrain + +[Term] +id: GO:0022017 +name: neuroblast division in pallium +namespace: biological_process +def: "The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021873 ! forebrain neuroblast division +relationship: part_of GO:0022013 ! pallium cell proliferation in forebrain + +[Term] +id: GO:0022018 +name: lateral ganglionic eminence cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0022019 +name: dorsal lateral ganglionic eminence cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022012 ! subpallium cell proliferation in forebrain +relationship: part_of GO:0022018 ! lateral ganglionic eminence cell proliferation + +[Term] +id: GO:0022020 +name: medial ganglionic eminence cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0022021 +name: caudal ganglionic eminence cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0022022 +name: septal cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of septal cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "septum cell proliferation" EXACT [] +is_a: GO:0022012 ! subpallium cell proliferation in forebrain + +[Term] +id: GO:0022023 +name: radial glial cell fate commitment in forebrain +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021781 ! glial cell fate commitment +is_a: GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain +relationship: part_of GO:0021861 ! forebrain radial glial cell differentiation + +[Term] +id: GO:0022024 +name: BMP signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "BMP signalling pathway involved in forebrain neuron fate commitment" EXACT [] +synonym: "bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment" EXACT [] +synonym: "bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment" EXACT [] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0022025 +name: leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:signaling] +synonym: "leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment" EXACT [] +is_a: GO:0048861 ! leukemia inhibitory factor signaling pathway +intersection_of: GO:0048861 ! leukemia inhibitory factor signaling pathway +intersection_of: part_of GO:0021877 ! forebrain neuron fate commitment +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0022026 +name: epidermal growth factor signaling pathway involved in forebrain neuron fate commitment +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "epidermal growth factor signalling pathway involved in forebrain neuron fate commitment" EXACT [] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +intersection_of: GO:0007173 ! epidermal growth factor receptor signaling pathway +intersection_of: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain +relationship: part_of GO:0021898 ! commitment of multipotent stem cells to neuronal lineage in forebrain + +[Term] +id: GO:0022027 +name: interkinetic nuclear migration +namespace: biological_process +def: "The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0007097 ! nuclear migration +relationship: part_of GO:0021846 ! cell proliferation in forebrain + +[Term] +id: GO:0022028 +name: tangential migration from the subventricular zone to the olfactory bulb +namespace: biological_process +def: "The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "rostral migratory stream migration" EXACT [] +is_a: GO:0022029 ! telencephalon cell migration +relationship: part_of GO:0021772 ! olfactory bulb development + +[Term] +id: GO:0022029 +name: telencephalon cell migration +namespace: biological_process +def: "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0021885 ! forebrain cell migration +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0022030 +name: telencephalon glial cell migration +namespace: biological_process +def: "The orderly movement of glial cells through the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0008347 ! glial cell migration +is_a: GO:0022029 ! telencephalon cell migration + +[Term] +id: GO:0022031 +name: telencephalon astrocyte cell migration +namespace: biological_process +def: "The orderly movement of an astrocyte cell through the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022030 ! telencephalon glial cell migration +is_a: GO:0043615 ! astrocyte cell migration + +[Term] +id: GO:0022032 +name: telencephalon oligodendrocyte cell migration +namespace: biological_process +def: "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022030 ! telencephalon glial cell migration + +[Term] +id: GO:0022033 +name: telencephalon microglial cell migration +namespace: biological_process +def: "The orderly movement of microglial cells through the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0022030 ! telencephalon glial cell migration + +[Term] +id: GO:0022034 +name: rhombomere cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0061351 ! neural precursor cell proliferation +relationship: part_of GO:0021546 ! rhombomere development + +[Term] +id: GO:0022035 +name: rhombomere cell migration +namespace: biological_process +def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700] +is_a: GO:0021535 ! cell migration in hindbrain +relationship: part_of GO:0021546 ! rhombomere development + +[Term] +id: GO:0022036 +name: rhombomere cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021546 ! rhombomere development + +[Term] +id: GO:0022037 +name: metencephalon development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030902 ! hindbrain development + +[Term] +id: GO:0022038 +name: corpus callosum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021537 ! telencephalon development + +[Term] +id: GO:0022400 +name: regulation of rhodopsin mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling." [GOC:mah] +synonym: "regulation of rhodopsin mediated signalling" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016056 ! rhodopsin mediated signaling pathway +relationship: regulates GO:0016056 ! rhodopsin mediated signaling pathway + +[Term] +id: GO:0022401 +name: negative adaptation of signaling pathway +namespace: biological_process +def: "The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus." [GOC:isa_complete] +synonym: "negative adaptation of signal transduction pathway" EXACT [] +synonym: "negative adaptation of signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0023058 ! adaptation of signaling pathway + +[Term] +id: GO:0022402 +name: cell cycle process +namespace: biological_process +def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle] +subset: gocheck_do_not_annotate +is_a: GO:0009987 ! cellular process +intersection_of: GO:0009987 ! cellular process +intersection_of: part_of GO:0007049 ! cell cycle +relationship: part_of GO:0007049 ! cell cycle + +[Term] +id: GO:0022403 +name: cell cycle phase +namespace: biological_process +def: "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GOC:mtg_cell_cycle] +subset: gocheck_do_not_annotate +is_a: GO:0044848 ! biological phase + +[Term] +id: GO:0022404 +name: molting cycle process +namespace: biological_process +def: "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." [GOC:isa_complete] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0042303 ! molting cycle + +[Term] +id: GO:0022405 +name: hair cycle process +namespace: biological_process +def: "A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:isa_complete] +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0042633 ! hair cycle + +[Term] +id: GO:0022406 +name: membrane docking +namespace: biological_process +def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684] +subset: goslim_pir +synonym: "membrane docking" EXACT [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0022407 +name: regulation of cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] +is_a: GO:0030155 ! regulation of cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098609 ! cell-cell adhesion +relationship: regulates GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0022408 +name: negative regulation of cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] +synonym: "down regulation of cell-cell adhesion" EXACT [] +synonym: "down-regulation of cell-cell adhesion" EXACT [] +synonym: "downregulation of cell-cell adhesion" EXACT [] +synonym: "inhibition of cell-cell adhesion" NARROW [] +is_a: GO:0007162 ! negative regulation of cell adhesion +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098609 ! cell-cell adhesion +relationship: negatively_regulates GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0022409 +name: positive regulation of cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] +synonym: "activation of cell-cell adhesion" NARROW [] +synonym: "stimulation of cell-cell adhesion" NARROW [] +synonym: "up regulation of cell-cell adhesion" EXACT [] +synonym: "up-regulation of cell-cell adhesion" EXACT [] +synonym: "upregulation of cell-cell adhesion" EXACT [] +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0045785 ! positive regulation of cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098609 ! cell-cell adhesion +relationship: positively_regulates GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0022410 +name: circadian sleep/wake cycle process +namespace: biological_process +def: "A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm." [GOC:isa_complete] +is_a: GO:0048512 ! circadian behavior +relationship: part_of GO:0042745 ! circadian sleep/wake cycle + +[Term] +id: GO:0022411 +name: cellular component disassembly +namespace: biological_process +alt_id: GO:0071845 +def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete] +subset: goslim_pir +synonym: "cell structure disassembly" EXACT [] +synonym: "cellular component disassembly at cellular level" EXACT [] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0022412 +name: cellular process involved in reproduction in multicellular organism +namespace: biological_process +def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete] +synonym: "reproductive cellular process in multicellular organism" EXACT [] +is_a: GO:0009987 ! cellular process +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0009987 ! cellular process +intersection_of: part_of GO:0032504 ! multicellular organism reproduction +relationship: part_of GO:0032504 ! multicellular organism reproduction + +[Term] +id: GO:0022413 +name: reproductive process in single-celled organism +namespace: biological_process +def: "A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism." [GOC:isa_complete] +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0032505 ! reproduction of a single-celled organism + +[Term] +id: GO:0022414 +name: reproductive process +namespace: biological_process +alt_id: GO:0044702 +def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] +synonym: "single organism reproductive process" RELATED [] +is_a: GO:0008150 ! biological_process +intersection_of: GO:0008150 ! biological_process +intersection_of: part_of GO:0000003 ! reproduction +disjoint_from: GO:0044848 ! biological phase +relationship: part_of GO:0000003 ! reproduction +created_by: jl +creation_date: 2012-09-19T15:56:06Z + +[Term] +id: GO:0022416 +name: chaeta development +namespace: biological_process +def: "The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell." [FBbt:00005177, GOC:bf, GOC:cjm, GOC:dos, GOC:isa_complete] +synonym: "bristle development" NARROW [GOC:bf, GOC:dos] +is_a: GO:0007423 ! sensory organ development + +[Term] +id: GO:0022417 +name: protein maturation by protein folding +namespace: biological_process +def: "The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein." [GOC:isa_complete] +is_a: GO:0006457 ! protein folding +is_a: GO:0051604 ! protein maturation + +[Term] +id: GO:0022600 +name: digestive system process +namespace: biological_process +def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio] +is_a: GO:0003008 ! system process +intersection_of: GO:0003008 ! system process +intersection_of: part_of GO:0007586 ! digestion +relationship: part_of GO:0007586 ! digestion + +[Term] +id: GO:0022601 +name: menstrual cycle phase +namespace: biological_process +def: "The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur." [GOC:dph, GOC:isa_complete, GOC:jid] +subset: gocheck_do_not_annotate +is_a: GO:0044848 ! biological phase + +[Term] +id: GO:0022602 +name: ovulation cycle process +namespace: biological_process +def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete] +synonym: "estrous cycle process" RELATED [] +synonym: "menstrual cycle process" RELATED [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0048511 ! rhythmic process +intersection_of: GO:0008150 ! biological_process +intersection_of: part_of GO:0042698 ! ovulation cycle +relationship: part_of GO:0042698 ! ovulation cycle + +[Term] +id: GO:0022603 +name: regulation of anatomical structure morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah] +synonym: "regulation of morphogenesis" EXACT [] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009653 ! anatomical structure morphogenesis +relationship: regulates GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0022604 +name: regulation of cell morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete] +synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000902 ! cell morphogenesis +relationship: regulates GO:0000902 ! cell morphogenesis + +[Term] +id: GO:0022605 +name: mammalian oogenesis stage +namespace: biological_process +def: "A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell." [GOC:isa_complete, GOC:mtg_sensu] +synonym: "mammalian oogenesis process" EXACT [] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0022606 +name: establishment of proximal/distal cell polarity +namespace: biological_process +def: "The specification and formation of the polarity of a cell along its proximal/distal axis." [GOC:isa_complete] +is_a: GO:0061162 ! establishment of monopolar cell polarity + +[Term] +id: GO:0022607 +name: cellular component assembly +namespace: biological_process +alt_id: GO:0071844 +def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +synonym: "cell structure assembly" EXACT [] +synonym: "cellular component assembly at cellular level" EXACT [] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0022608 +name: multicellular organism adhesion +namespace: biological_process +def: "The attachment of a multicellular organism to a substrate or other organism." [GOC:isa_complete] +is_a: GO:0022610 ! biological adhesion +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0022609 +name: multicellular organism adhesion to substrate +namespace: biological_process +def: "The attachment of a multicellular organism to a surface or material." [GOC:isa_complete] +is_a: GO:0022608 ! multicellular organism adhesion + +[Term] +id: GO:0022610 +name: biological adhesion +namespace: biological_process +def: "The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions." [GOC:isa_complete] +subset: goslim_pir +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase + +[Term] +id: GO:0022611 +name: dormancy process +namespace: biological_process +def: "A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated." [GOC:isa_complete, GOC:PO_curators, PO_REF:00009] +comment: In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium. +synonym: "multicellular organism dormancy process" NARROW [] +synonym: "spore dormancy process" NARROW [GOC:PO_curators] +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0022612 +name: gland morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048732 ! gland development + +[Term] +id: GO:0022613 +name: ribonucleoprotein complex biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah] +synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah] +synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah] +is_a: GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0022614 +name: membrane to membrane docking +namespace: biological_process +def: "The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere." [GOC:isa_complete] +synonym: "membrane-membrane docking" EXACT [] +is_a: GO:0022406 ! membrane docking + +[Term] +id: GO:0022615 +name: protein to membrane docking +namespace: biological_process +def: "The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete] +synonym: "protein-membrane docking" EXACT [] +is_a: GO:0022406 ! membrane docking + +[Term] +id: GO:0022616 +name: DNA strand elongation +namespace: biological_process +def: "The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand." [GOC:isa_complete, GOC:mah] +is_a: GO:0006259 ! DNA metabolic process +relationship: has_part GO:0071897 ! DNA biosynthetic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12633 xsd:anyURI + +[Term] +id: GO:0022617 +name: extracellular matrix disassembly +namespace: biological_process +def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0030198 ! extracellular matrix organization + +[Term] +id: GO:0022618 +name: ribonucleoprotein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl] +subset: goslim_chembl +subset: goslim_generic +synonym: "protein-RNA complex assembly" EXACT [] +synonym: "RNA-protein complex assembly" EXACT [] +synonym: "RNP complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0071826 ! ribonucleoprotein complex subunit organization +relationship: part_of GO:0022613 ! ribonucleoprotein complex biogenesis + +[Term] +id: GO:0022619 +name: generative cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte." [GOC:isa_complete] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0055046 ! microgametogenesis + +[Term] +id: GO:0022620 +name: vegetative cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube." [GOC:isa_complete] +synonym: "tube cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0055046 ! microgametogenesis + +[Term] +id: GO:0022622 +name: root system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure." [GOC:isa_complete] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0022623 +name: proteasome-activating nucleotidase complex +namespace: cellular_component +def: "A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner." [GOC:bf, GOC:mtg_sensu, PMID:19363223, PMID:19481528] +synonym: "PAN" EXACT [PMID:19363223, PMID:19481528] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0022624 ! proteasome accessory complex + +[Term] +id: GO:0022624 +name: proteasome accessory complex +namespace: cellular_component +def: "A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex." [GOC:mtg_sensu] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000502 ! proteasome complex + +[Term] +id: GO:0022625 +name: cytosolic large ribosomal subunit +namespace: cellular_component +alt_id: GO:0005842 +alt_id: GO:0009282 +alt_id: GO:0030498 +alt_id: GO:0030872 +def: "The large subunit of a ribosome located in the cytosol." [GOC:mtg_sensu] +synonym: "50S ribosomal subunit" NARROW [] +synonym: "60S ribosomal subunit" NARROW [] +synonym: "eukaryotic ribosomal LSU" NARROW [] +synonym: "prokaryotic large ribosomal subunit" NARROW [] +is_a: GO:0015934 ! large ribosomal subunit +intersection_of: GO:0015934 ! large ribosomal subunit +intersection_of: part_of GO:0022626 ! cytosolic ribosome +relationship: part_of GO:0022626 ! cytosolic ribosome + +[Term] +id: GO:0022626 +name: cytosolic ribosome +namespace: cellular_component +alt_id: GO:0005830 +alt_id: GO:0009281 +alt_id: GO:0030871 +def: "A ribosome located in the cytosol." [GOC:mtg_sensu] +synonym: "70S ribosome" NARROW [] +synonym: "80S ribosome" NARROW [] +is_a: GO:0005840 ! ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0022627 +name: cytosolic small ribosomal subunit +namespace: cellular_component +alt_id: GO:0005843 +alt_id: GO:0009283 +alt_id: GO:0030499 +alt_id: GO:0030873 +def: "The small subunit of a ribosome located in the cytosol." [GOC:mtg_sensu] +synonym: "30S ribosomal subunit" NARROW [] +synonym: "40S ribosomal subunit" NARROW [] +synonym: "eukaryotic ribosomal SSU" NARROW [] +synonym: "prokaryotic small ribosomal subunit" NARROW [] +is_a: GO:0015935 ! small ribosomal subunit +intersection_of: GO:0015935 ! small ribosomal subunit +intersection_of: part_of GO:0022626 ! cytosolic ribosome +relationship: part_of GO:0022626 ! cytosolic ribosome + +[Term] +id: GO:0022628 +name: chloroplast large ribosomal subunit +namespace: cellular_component +def: "The large subunit of a ribosome contained within a chloroplast." [GOC:mtg_sensu] +synonym: "chloroplast ribosomal large subunit complex" EXACT [] +synonym: "chloroplast ribosomal LSU complex" EXACT [] +is_a: GO:0000311 ! plastid large ribosomal subunit +intersection_of: GO:0015934 ! large ribosomal subunit +intersection_of: part_of GO:0043253 ! chloroplast ribosome +relationship: part_of GO:0043253 ! chloroplast ribosome + +[Term] +id: GO:0022629 +name: chloroplast small ribosomal subunit +namespace: cellular_component +def: "The small subunit of a ribosome contained within a chloroplast." [GOC:mtg_sensu] +synonym: "chloroplast ribosomal small subunit complex" EXACT [] +synonym: "chloroplast ribosomal SSU complex" EXACT [] +is_a: GO:0000312 ! plastid small ribosomal subunit +intersection_of: GO:0015935 ! small ribosomal subunit +intersection_of: part_of GO:0043253 ! chloroplast ribosome +relationship: part_of GO:0043253 ! chloroplast ribosome + +[Term] +id: GO:0022803 +name: passive transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0022814 +def: "Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +synonym: "facilitated diffusion" RELATED [] +synonym: "porters" BROAD [] +synonym: "uniporter activity z" NARROW [] +xref: Reactome:R-HSA-429767 "Passive I- efflux mediated by SMCT1" +xref: Wikipedia:Facilitated_diffusion +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0022804 +name: active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] +synonym: "active carrier activity" EXACT [] +synonym: "carrier activity" EXACT [] +synonym: "permease activity" EXACT [] +synonym: "pump activity" EXACT [] +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0022809 +name: mobile ion carrier activity +namespace: molecular_function +def: "Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +synonym: "ionophore" BROAD [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0022810 +name: membrane potential driven uniporter activity +namespace: molecular_function +def: "Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +synonym: "porter" BROAD [] +is_a: GO:0015292 ! uniporter activity + +[Term] +id: GO:0022815 +name: obsolete large uncharged polar molecule transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term. +synonym: "large uncharged polar molecule transmembrane transporter activity" EXACT [] +is_obsolete: true +replaced_by: GO:0022857 + +[Term] +id: GO:0022818 +name: sodium ion uniporter activity +namespace: molecular_function +def: "Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0022810 ! membrane potential driven uniporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0022819 +name: potassium ion uniporter activity +namespace: molecular_function +def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0022810 ! membrane potential driven uniporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0022821 +name: potassium ion antiporter activity +namespace: molecular_function +def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +is_a: GO:0015298 ! solute:cation antiporter activity + +[Term] +id: GO:0022824 +name: transmitter-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +synonym: "ionotropic neurotransmitter receptor activity" NARROW [GOC:bf, GOC:sart] +is_a: GO:0005230 ! extracellular ligand-gated ion channel activity +is_a: GO:0022835 ! transmitter-gated channel activity + +[Term] +id: GO:0022825 +name: obsolete copper-exporting ATPase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it was a placeholder during work on transporter terms, and was not defined. +synonym: "copper-exporting ATPase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0043682 + +[Term] +id: GO:0022828 +name: phosphorylation-gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0022829 +name: wide pore channel activity +namespace: molecular_function +def: "Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts." [GOC:mtg_transport, ISBN:0815340729] +synonym: "gap junction activity" NARROW [] +synonym: "non-gated, wide pore channel activity" EXACT [] +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0022831 +name: narrow pore, gated channel activity +namespace: molecular_function +def: "Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus." [GOC:mtg_transport, ISBN:0815340729] +synonym: "ion channels" RELATED [] +xref: Wikipedia:Ion_channels +is_a: GO:0022842 ! narrow pore channel activity + +[Term] +id: GO:0022832 +name: voltage-gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0022834 +name: ligand-gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0022835 +name: transmitter-gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +synonym: "extracellular substance gated channel activity" EXACT [] +synonym: "neurotransmitter-gated channel activity" EXACT [] +is_a: GO:0022834 ! ligand-gated channel activity +is_a: GO:0030594 ! neurotransmitter receptor activity + +[Term] +id: GO:0022836 +name: gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus." [GOC:mtg_transport] +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0022839 +name: ion gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus." [GOC:mtg_transport] +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0022840 +name: leak channel activity +namespace: molecular_function +def: "Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022842 ! narrow pore channel activity + +[Term] +id: GO:0022841 +name: potassium ion leak channel activity +namespace: molecular_function +def: "Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0022840 ! leak channel activity + +[Term] +id: GO:0022842 +name: narrow pore channel activity +namespace: molecular_function +def: "Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0022843 +name: voltage-gated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] +xref: Reactome:R-HSA-2534378 "Hv1 Mediated H+ Permeability" +xref: Reactome:R-HSA-6788999 "HV1-mediated H+ transfer" +is_a: GO:0005244 ! voltage-gated ion channel activity +is_a: GO:0005261 ! cation channel activity + +[Term] +id: GO:0022848 +name: acetylcholine-gated cation-selective channel activity +namespace: molecular_function +alt_id: GO:0004889 +alt_id: GO:0016904 +def: "Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine." [GOC:mah, PMID:2466967] +synonym: "acetylcholine-activated cation-selective channel activity" EXACT [] +synonym: "acetylcholine-gated cation channel activity" EXACT [] +synonym: "ionotropic acetylcholine receptor activity" EXACT [] +synonym: "nAChR" EXACT [] +synonym: "nicotinergic acetylcholine receptor activity" EXACT [] +synonym: "nicotinic acetylcholine-activated cation-selective channel activity" EXACT [GOC:bf] +is_a: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity +is_a: GO:1904315 ! transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential + +[Term] +id: GO:0022849 +name: glutamate-gated calcium ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0004970 ! ionotropic glutamate receptor activity +is_a: GO:0099604 ! ligand-gated calcium channel activity + +[Term] +id: GO:0022850 +name: serotonin-gated cation-selective channel activity +namespace: molecular_function +alt_id: GO:0005232 +def: "Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'G protein-coupled serotonin receptor activity ; GO:0004993'. +synonym: "5-hydroxytryptamine-gated receptor-channel" NARROW [] +synonym: "serotonin-activated cation-selective channel activity" EXACT [] +synonym: "serotonin-gated cation channel activity" NARROW [] +xref: Reactome:R-HSA-975311 "HTR3 pentamer:5HT transports Na+,K+, and Ca2+" +is_a: GO:0022824 ! transmitter-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity +relationship: part_of GO:0007210 ! serotonin receptor signaling pathway + +[Term] +id: GO:0022851 +name: GABA-gated chloride ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0016917 ! GABA receptor activity +is_a: GO:0022824 ! transmitter-gated ion channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity + +[Term] +id: GO:0022852 +name: glycine-gated chloride ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0022824 ! transmitter-gated ion channel activity +is_a: GO:0099095 ! ligand-gated anion channel activity + +[Term] +id: GO:0022853 +name: active ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0022804 ! active transmembrane transporter activity + +[Term] +id: GO:0022854 +name: obsolete active large uncharged polar molecule transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term. +synonym: "active large uncharged polar molecule transmembrane transporter activity" EXACT [] +is_obsolete: true +replaced_by: GO:0022804 + +[Term] +id: GO:0022855 +name: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "glucose PTS transporter activity" EXACT [] +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity + +[Term] +id: GO:0022856 +name: protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "sorbitol PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015576 ! sorbitol transmembrane transporter activity + +[Term] +id: GO:0022857 +name: transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0005386 +alt_id: GO:0015563 +alt_id: GO:0015646 +alt_id: GO:0022891 +alt_id: GO:0022892 +def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "substrate-specific transmembrane transporter activity" RELATED [] +synonym: "substrate-specific transporter activity" RELATED [] +synonym: "uptake permease activity" RELATED [] +synonym: "uptake transmembrane transporter activity" RELATED [] +xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61" +xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate" +xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate" +xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA" +xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome" +xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol" +is_a: GO:0005215 ! transporter activity +relationship: part_of GO:0055085 ! transmembrane transport + +[Term] +id: GO:0022858 +name: alanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +relationship: part_of GO:0032328 ! alanine transport + +[Term] +id: GO:0022859 +name: dephosphorylation-gated channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0022865 +name: obsolete transmembrane electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics." [GOC:mtg_transport, ISBN:0815340729, TC:5] +comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process. +xref: TC:5 +is_obsolete: true + +[Term] +id: GO:0022866 +name: obsolete transmembrane 1-electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. Enables transfer of one electron across a membrane." [GOC:mtg_transport, ISBN:0815340729, TC:5.B] +comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process. +synonym: "transmembrane one-electron transfer carrier" EXACT [GOC:mah] +is_obsolete: true + +[Term] +id: GO:0022867 +name: obsolete transmembrane 2-electron transfer carrier +namespace: molecular_function +def: "OBSOLETE. Enables transfer of two electrons across a membrane." [GOC:mtg_transport, ISBN:0815340729, TC:5.A] +comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process. +synonym: "transmembrane two-electron transfer carrier" EXACT [GOC:mah] +is_obsolete: true + +[Term] +id: GO:0022869 +name: protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "lactose PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015155 ! lactose transmembrane transporter activity + +[Term] +id: GO:0022870 +name: protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "mannose PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015578 ! mannose transmembrane transporter activity + +[Term] +id: GO:0022871 +name: protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "sorbose PTS transporter activity" EXACT [] +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0019194 ! sorbose transmembrane transporter activity + +[Term] +id: GO:0022872 +name: protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "mannitol PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015575 ! mannitol transmembrane transporter activity + +[Term] +id: GO:0022873 +name: protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "maltose PTS transporter activity" EXACT [] +is_a: GO:0005363 ! maltose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity + +[Term] +id: GO:0022874 +name: protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "cellobiose PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0019191 ! cellobiose transmembrane transporter activity + +[Term] +id: GO:0022875 +name: protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "galactitol PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015577 ! galactitol transmembrane transporter activity + +[Term] +id: GO:0022876 +name: protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "galactosamine PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0019196 ! galactosamine transmembrane transporter activity + +[Term] +id: GO:0022877 +name: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "fructose PTS transporter activity" EXACT [] +is_a: GO:0005353 ! fructose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity + +[Term] +id: GO:0022878 +name: protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "sucrose PTS transporter activity" EXACT [] +xref: MetaCyc:SUCROSEPHOSPHO-RXN +is_a: GO:0008515 ! sucrose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity + +[Term] +id: GO:0022879 +name: protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "trehalose PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015574 ! trehalose transmembrane transporter activity + +[Term] +id: GO:0022880 +name: protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "N-acetylglucosamine PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015572 ! N-acetylglucosamine transmembrane transporter activity +is_a: GO:0015574 ! trehalose transmembrane transporter activity + +[Term] +id: GO:0022881 +name: protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "N-acetylgalactosamine PTS transporter activity" EXACT [] +is_a: GO:0005355 ! glucose transmembrane transporter activity +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015571 ! N-acetylgalactosamine transmembrane transporter activity + +[Term] +id: GO:0022882 +name: protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] +synonym: "beta-glucoside PTS transporter activity" EXACT [] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +is_a: GO:0015573 ! beta-glucoside transmembrane transporter activity + +[Term] +id: GO:0022883 +name: zinc efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] +synonym: "zinc efflux permease activity" EXACT [] +is_a: GO:0005385 ! zinc ion transmembrane transporter activity +is_a: GO:0046583 ! cation efflux transmembrane transporter activity + +[Term] +id: GO:0022884 +name: macromolecule transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0022885 +name: bacteriocin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a bacteriocin from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0043213 ! bacteriocin transport + +[Term] +id: GO:0022886 +name: channel-forming ionophore activity +namespace: molecular_function +def: "Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive." [GOC:mtg_transport, ISBN:0815340729] +synonym: "ionophore activity" BROAD [] +is_a: GO:0015267 ! channel activity + +[Term] +id: GO:0022889 +name: serine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +relationship: part_of GO:0032329 ! serine transport + +[Term] +id: GO:0022890 +name: inorganic cation transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015082 +def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "di-, tri-valent inorganic cation transmembrane transporter activity" NARROW [GOC:mah] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity + +[Term] +id: GO:0022893 +name: low-affinity tryptophan transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015510 +def: "Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mtg_transport, ISBN:0815340729] +synonym: "low-affinity tryptophan permease activity" RELATED [] +is_a: GO:0015196 ! L-tryptophan transmembrane transporter activity + +[Term] +id: GO:0022894 +name: Intermediate conductance calcium-activated potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, OMIM:602754] +synonym: "IK calcium-activated potassium channel activity" EXACT [] +synonym: "IK KCa channels" EXACT [] +synonym: "intermdiate conductance KCa channels" EXACT [] +is_a: GO:0015269 ! calcium-activated potassium channel activity + +[Term] +id: GO:0022897 +name: proton-dependent peptide secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement." [GOC:mtg_transport] +synonym: "hydrogen/oligopeptide symporter" RELATED [] +is_a: GO:0015291 ! secondary active transmembrane transporter activity +relationship: part_of GO:1902600 ! proton transmembrane transport + +[Term] +id: GO:0022898 +name: regulation of transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] +is_a: GO:0032409 ! regulation of transporter activity +is_a: GO:0034762 ! regulation of transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022857 ! transmembrane transporter activity +relationship: regulates GO:0022857 ! transmembrane transporter activity + +[Term] +id: GO:0022900 +name: electron transport chain +namespace: biological_process +def: "A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient." [GOC:mtg_electron_transport] +subset: goslim_pir +xref: Wikipedia:Electron_transport_chain +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0022904 +name: respiratory electron transport chain +namespace: biological_process +def: "A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient." [GOC:mtg_electron_transport, ISBN:0716720094] +synonym: "6-phosphofructokinase reduction" RELATED [] +synonym: "dihydrobiopterin reduction" RELATED [] +synonym: "dihydrolipoamide reduction" RELATED [] +synonym: "dihydrolipoylprotein reduction" RELATED [] +synonym: "dihydropteridine reduction" RELATED [] +synonym: "electron transfer" EXACT [] +synonym: "other pathways of electron transport" RELATED [] +synonym: "oxidized glutathione reduction" RELATED [] +synonym: "protein-disulfide reduction" RELATED [] +xref: Wikipedia:Electron_transfer +is_a: GO:0022900 ! electron transport chain +relationship: part_of GO:0045333 ! cellular respiration + +[Term] +id: GO:0023002 +name: nuclear migration to embryo sac poles +namespace: biological_process +def: "Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell." [GOC:jid, GOC:mtg_plant, ISBN:047186840X] +synonym: "nuclear migration to female gametophyte poles" EXACT [] +synonym: "nuclear migration to megagametophyte poles" EXACT [] +synonym: "nucleus migration to embryo sac poles" EXACT [] +synonym: "nucleus migration to female gametophyte poles" EXACT [] +synonym: "nucleus migration to megagametophyte poles" EXACT [] +is_a: GO:0009562 ! embryo sac nuclear migration + +[Term] +id: GO:0023003 +name: nuclear migration to the embryo sac center +namespace: biological_process +def: "Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell." [GOC:jid, GOC:mtg_plant, ISBN:047186840X] +synonym: "nuclear migration to the embryo sac centre" EXACT [] +synonym: "nuclear migration to the female gametophyte center" EXACT [] +synonym: "nuclear migration to the female gametophyte centre" EXACT [] +synonym: "nuclear migration to the megagametophyte center" EXACT [] +synonym: "nuclear migration to the megagametophyte centre" EXACT [] +synonym: "nucleus migration to the female gametophyte center" EXACT [] +synonym: "nucleus migration to the female gametophyte centre" EXACT [] +is_a: GO:0009562 ! embryo sac nuclear migration + +[Term] +id: GO:0023004 +name: obsolete activation of dopamine receptor signaling pathway +namespace: biological_process +def: "OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "activation of dopamine receptor signaling pathway" EXACT [] +synonym: "activation of dopamine receptor signalling pathway" EXACT [GOC:mah] +synonym: "initiation of dopamine receptor signaling pathway" RELATED [] +synonym: "stimulation of dopamine receptor signaling pathway" EXACT [] +is_obsolete: true +consider: GO:0060161 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023005 +name: obsolete signal initiation by neurotransmitter +namespace: biological_process +def: "OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by neurotransmitter" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0030594 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023006 +name: obsolete signal initiation by amino acid +namespace: biological_process +def: "OBSOLETE. The process in which an amino acid signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by amino acid" EXACT [] +is_obsolete: true +consider: GO:0007215 +consider: GO:0008066 +consider: GO:0071230 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023007 +name: obsolete ligand binding to T cell receptor +namespace: biological_process +def: "OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process." [GOC:jid, GOC:mtg_signal] +comment: This term was made obsolete because it is describing a binding molecular function. +synonym: "ligand binding to T cell receptor" EXACT [] +is_obsolete: true +consider: GO:0042101 +consider: GO:0042608 +consider: GO:0050852 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023009 +name: obsolete initiation of T cell receptor signaling +namespace: biological_process +def: "OBSOLETE. The process in which a signal causes activation of T cell receptor signaling." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "initiation of T cell receptor signaling" EXACT [] +synonym: "initiation of T cell receptor signalling" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0038023 +consider: GO:0042101 +consider: GO:0048018 +consider: GO:0050852 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023010 +name: obsolete regulation of initiation of T cell receptor signaling +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "regulation of initiation of T cell receptor signaling" EXACT [] +synonym: "regulation of initiation of T cell receptor signalling" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0050856 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023011 +name: obsolete positive regulation of initiation of T cell receptor signaling +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "positive regulation of initiation of T cell receptor signaling" EXACT [] +synonym: "positive regulation of initiation of T cell receptor signalling" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0050862 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023012 +name: obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor +namespace: biological_process +def: "OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling." [GOC:mtg_signal] +comment: This term was made obsolete because it is describing a binding molecular function. +synonym: "initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor" EXACT [] +synonym: "initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0042101 +consider: GO:0050852 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023014 +name: signal transduction by protein phosphorylation +namespace: biological_process +def: "A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate." [GOC:mtg_signal, GOC:signaling] +synonym: "signal transduction via phosphorylation event" RELATED [GOC:bf] +synonym: "signal transmission via phosphorylation event" RELATED [GOC:bf] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0007165 ! signal transduction +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023015 +name: signal transduction by cis-phosphorylation +namespace: biological_process +def: "A process in which the transfer of one or more phosphate groups by a kinase to a residue in the same kinase molecule transmits a signal. For example, ligand-binding can induce autophosphorylation of the activated receptor, creating binding sites for intracellular signaling molecules." [GOC:bf, GOC:mtg_signal, GOC:signaling] +synonym: "signal transduction via a cis-phosphorylation event" RELATED [GOC:bf] +synonym: "signal transmission via a cis-phosphorylation event" RELATED [GOC:bf] +synonym: "signal transmission via auto-phosphorylation" RELATED [] +is_a: GO:0023014 ! signal transduction by protein phosphorylation +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023016 +name: signal transduction by trans-phosphorylation +namespace: biological_process +def: "A process in which the transfer of one or more phosphate groups by a kinase to a residue in a different protein molecule transmits a signal." [GOC:bf, GOC:mtg_signal] +synonym: "signal transduction via a trans-phosphorylation event" RELATED [GOC:bf] +synonym: "signal transmission via a trans-phosphorylation event" RELATED [GOC:bf] +is_a: GO:0023014 ! signal transduction by protein phosphorylation +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023017 +name: obsolete signal transmission via diffusible molecule +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via a diffusible molecule." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via diffusible molecule" EXACT [] +synonym: "signaling via diffusible mediator" EXACT [] +is_obsolete: true +consider: GO:0007267 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023018 +name: obsolete T cell activation of signal transmission via diffusible molecule +namespace: biological_process +def: "OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "T cell activation of signal transmission via diffusible molecule" EXACT [] +is_obsolete: true +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023019 +name: signal transduction involved in regulation of gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] +synonym: "regulation of gene expression as a consequence of signal transmission" RELATED [GOC:bf] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0010468 ! regulation of gene expression +relationship: part_of GO:0010468 ! regulation of gene expression +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023020 +name: obsolete regulation of gene expression as a consequence of T cell signal transmission +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "regulation of gene expression as a consequence of T cell signal transmission" EXACT [] +is_obsolete: true +consider: GO:0023019 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023021 +name: termination of signal transduction +namespace: biological_process +def: "The signaling process in which signal transduction is brought to an end rather than being reversibly modulated." [GOC:mtg_signal] +comment: Note that this term encompasses both the control point when the instruction is given for the process to cease and the actual cessation of the process. A process can persist for some time after that signal that induced the process is withdrawn. +is_a: GO:0009968 ! negative regulation of signal transduction +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023022 +name: termination of T cell signal transduction +namespace: biological_process +def: "The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated." [GOC:mtg_signal] +is_a: GO:0023021 ! termination of signal transduction +is_a: GO:0050860 ! negative regulation of T cell receptor signaling pathway +relationship: part_of GO:0050852 ! T cell receptor signaling pathway +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023023 +name: MHC protein complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the major histocompatibility complex." [GOC:mtg_signal, GOC:vw] +is_a: GO:0044877 ! protein-containing complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023024 +name: MHC class I protein complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the class I major histocompatibility complex." [GOC:mtg_signal, GOC:vw] +is_a: GO:0023023 ! MHC protein complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023025 +name: MHC class Ib protein complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the class Ib major histocompatibility complex." [GOC:mtg_signal, GOC:vw] +is_a: GO:0023023 ! MHC protein complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023026 +name: MHC class II protein complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the class II major histocompatibility complex." [GOC:mtg_signal, GOC:vw] +is_a: GO:0023023 ! MHC protein complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023027 +name: MHC class I protein binding, via antigen binding groove +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the antigen binding groove." [GOC:mtg_signal, GOC:vw] +is_a: GO:0042288 ! MHC class I protein binding +relationship: part_of GO:0023024 ! MHC class I protein complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023028 +name: MHC class I protein binding, via lateral surface +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the lateral surface." [GOC:mtg_signal, GOC:vw] +is_a: GO:0042288 ! MHC class I protein binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023029 +name: MHC class Ib protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules." [GOC:mtg_signal, GOC:vw] +is_a: GO:0042287 ! MHC protein binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023030 +name: MHC class Ib protein binding, via antigen binding groove +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove." [GOC:mtg_signal, GOC:vw] +is_a: GO:0023029 ! MHC class Ib protein binding +relationship: part_of GO:0023025 ! MHC class Ib protein complex binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023031 +name: MHC class Ib protein binding, via lateral surface +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the lateral surface." [GOC:mtg_signal, GOC:vw] +is_a: GO:0023029 ! MHC class Ib protein binding +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023035 +name: CD40 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mtg_signal, GOC:signaling, PMID:11348017] +synonym: "CD40 signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023036 +name: obsolete initiation of signal transduction +namespace: biological_process +def: "OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. Note that this term was intended for the annotation of both ligands and receptors. +synonym: "initiation of signal transduction" EXACT [] +synonym: "signal reception" RELATED [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038023 +consider: GO:0048018 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023037 +name: obsolete signal initiation by light +namespace: biological_process +def: "OBSOLETE. The process in which a light signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by light" EXACT [] +is_obsolete: true +consider: GO:0009785 +consider: GO:0009881 +consider: GO:0010017 +consider: GO:0010018 +consider: GO:0010161 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023038 +name: obsolete signal initiation by diffusible mediator +namespace: biological_process +def: "OBSOLETE. The process in which a diffusible signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by diffusible mediator" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038001 +consider: GO:0038023 +consider: GO:0048018 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023039 +name: obsolete signal initiation by physical damage +namespace: biological_process +def: "OBSOLETE. The process in which a physical damage signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by physical damage" EXACT [] +is_obsolete: true +consider: GO:0033554 +consider: GO:0038023 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023040 +name: obsolete signaling via ionic flux +namespace: biological_process +def: "OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signaling via ionic flux" EXACT [] +synonym: "signalling via ionic flux" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023041 +name: neuronal signal transduction +namespace: biological_process +def: "The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular." [GOC:mtg_signal] +is_a: GO:0007165 ! signal transduction +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023042 +name: obsolete signaling via protein/peptide mediator +namespace: biological_process +def: "OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signaling via protein/peptide mediator" EXACT [] +synonym: "signalling via protein/peptide mediator" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023043 +name: obsolete signaling via lipid mediator +namespace: biological_process +def: "OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signaling via lipid mediator" EXACT [] +synonym: "signalling via lipid mediator" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0014065 +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023044 +name: obsolete signaling via chemical mediator +namespace: biological_process +def: "OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signaling via chemical mediator" EXACT [] +synonym: "signalling via chemical mediator" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023045 +name: signal transduction by conformational transition +namespace: biological_process +def: "A process where induction of a conformational change in a molecule transmits a signal to that molecule." [GOC:bf, GOC:mtg_signal] +synonym: "signal transduction via conformational transition" RELATED [GOC:bf] +synonym: "signal transmission via conformational transition" RELATED [GOC:bf] +is_a: GO:0007165 ! signal transduction +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023047 +name: obsolete signal initiation by chemical mediator +namespace: biological_process +def: "OBSOLETE. The process in which a chemical signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by chemical mediator" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038023 +consider: GO:0070887 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023048 +name: obsolete signal initiation by lipid mediator +namespace: biological_process +def: "OBSOLETE. The process in which a lipid signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by lipid mediator" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0045125 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023049 +name: obsolete signal initiation by protein/peptide mediator +namespace: biological_process +def: "OBSOLETE. The process in which a protein/peptide signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by protein/peptide mediator" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038023 +consider: GO:0048018 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023050 +name: obsolete consequence of signal transmission +namespace: biological_process +def: "OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state." [GOC:mtg_signal] +comment: This term was made obsolete because the term is no longer needed. +synonym: "consequence of signal transmission" EXACT [] +synonym: "signal termination" EXACT [] +is_obsolete: true +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023051 +name: regulation of signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] +synonym: "regulation of signaling process" RELATED [GOC:bf] +synonym: "regulation of signalling process" RELATED [GOC:mah] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0023052 ! signaling +relationship: regulates GO:0023052 ! signaling +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023052 +name: signaling +namespace: biological_process +alt_id: GO:0023046 +alt_id: GO:0044700 +def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] +comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. +subset: goslim_agr +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pombe +subset: goslim_yeast +synonym: "biological signaling" EXACT [] +synonym: "signaling process" EXACT [] +synonym: "signalling" EXACT [] +synonym: "signalling process" RELATED [GOC:mah] +synonym: "single organism signaling" RELATED [] +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +created_by: jl +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023053 +name: obsolete signal initiation by mechanical effect +namespace: biological_process +def: "OBSOLETE. The process in which a mechanical signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by mechanical effect" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038023 +consider: GO:0071260 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023054 +name: obsolete signal initiation by stretch effect +namespace: biological_process +def: "OBSOLETE. The process in which a stretch signal causes activation of a receptor." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by stretch effect" EXACT [] +is_obsolete: true +consider: GO:0007165 +consider: GO:0038023 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023055 +name: obsolete signal initiation by peptide hormone +namespace: biological_process +def: "OBSOLETE. The process in which a signal is initiated by a peptide hormone." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal initiation by peptide hormone" EXACT [] +is_obsolete: true +consider: GO:0004879 +consider: GO:0005179 +consider: GO:0009755 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023056 +name: positive regulation of signaling +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal] +synonym: "positive regulation of signaling process" RELATED [GOC:bf] +synonym: "positive regulation of signalling process" EXACT [GOC:mah] +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0023052 ! signaling +relationship: positively_regulates GO:0023052 ! signaling +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023057 +name: negative regulation of signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal] +synonym: "negative regulation of signaling process" RELATED [GOC:bf] +synonym: "negative regulation of signalling process" RELATED [GOC:mah] +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0023052 ! signaling +relationship: negatively_regulates GO:0023052 ! signaling +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023058 +name: adaptation of signaling pathway +namespace: biological_process +def: "The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus." [GOC:mtg_signal] +synonym: "adaptation of signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023059 +name: positive adaptation of signaling pathway +namespace: biological_process +def: "The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus." [GOC:mtg_signal] +synonym: "positive adaptation of signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0023058 ! adaptation of signaling pathway +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023060 +name: obsolete signal transmission +namespace: biological_process +def: "OBSOLETE. The process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "signal transmission" EXACT [] +is_obsolete: true +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023061 +name: signal release +namespace: biological_process +def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] +synonym: "signal secretion" EXACT [GOC:bf] +is_a: GO:0032940 ! secretion by cell +intersection_of: GO:0032940 ! secretion by cell +intersection_of: part_of GO:0007267 ! cell-cell signaling +relationship: part_of GO:0007267 ! cell-cell signaling +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023062 +name: obsolete signal transmission via transcytosis +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side." [GOC:mtg_signal, ISBN:0716731363] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via transcytosis" EXACT [] +is_obsolete: true +consider: GO:0023052 +consider: GO:0045056 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023065 +name: obsolete signal transmission via blood +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via blood." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via blood" EXACT [] +is_obsolete: true +consider: GO:0010232 +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023066 +name: obsolete signal transmission via vascular system +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via the vascular system." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via vascular system" EXACT [] +is_obsolete: true +consider: GO:0010232 +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023067 +name: obsolete signal transmission via lymphatic system +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via the lymphatic system." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via lymphatic system" EXACT [] +is_obsolete: true +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023068 +name: obsolete signal transmission via phloem +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via the phloem." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via phloem" EXACT [] +is_obsolete: true +consider: GO:0010233 +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023069 +name: obsolete signal transmission via xylem +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via the xylem." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via xylem" EXACT [] +is_obsolete: true +consider: GO:0010232 +consider: GO:0023052 +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0023070 +name: obsolete signal transmission via air +namespace: biological_process +def: "OBSOLETE. The process in which a signal is conveyed via the air." [GOC:mtg_signal] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "signal transmission via air" EXACT [] +is_obsolete: true +creation_date: 2010-02-16T09:30:50Z + +[Term] +id: GO:0030001 +name: metal ion transport +namespace: biological_process +def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "heavy metal ion transport" NARROW [] +is_a: GO:0006812 ! cation transport + +[Term] +id: GO:0030002 +name: cellular anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of anions at the level of a cell." [GOC:ceb, GOC:mah] +is_a: GO:0006873 ! cellular ion homeostasis +is_a: GO:0055081 ! anion homeostasis + +[Term] +id: GO:0030003 +name: cellular cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cations at the level of a cell." [GOC:ceb, GOC:mah] +is_a: GO:0006873 ! cellular ion homeostasis +is_a: GO:0055080 ! cation homeostasis + +[Term] +id: GO:0030004 +name: cellular monovalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell." [GOC:ai, GOC:mah] +is_a: GO:0030003 ! cellular cation homeostasis +is_a: GO:0055067 ! monovalent inorganic cation homeostasis + +[Term] +id: GO:0030005 +name: obsolete cellular di-, tri-valent inorganic cation homeostasis +namespace: biological_process +def: "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell." [GOC:ceb, GOC:mah] +synonym: "cellular di-, tri-valent inorganic cation homeostasis" EXACT [] +is_obsolete: true +consider: GO:0072503 +consider: GO:0072504 + +[Term] +id: GO:0030006 +name: obsolete heavy cellular metal ion homeostasis +namespace: biological_process +def: "OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn." [GOC:kd, GOC:mah] +comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). +synonym: "heavy cellular metal ion homeostasis" EXACT [] +is_obsolete: true +consider: GO:0006875 + +[Term] +id: GO:0030007 +name: cellular potassium ion homeostasis +namespace: biological_process +alt_id: GO:0017079 +def: "Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell." [GOC:mah] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0030004 ! cellular monovalent inorganic cation homeostasis +is_a: GO:0055075 ! potassium ion homeostasis + +[Term] +id: GO:0030008 +name: TRAPP complex +namespace: cellular_component +def: "A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active." [GOC:bhm, GOC:vw, PMID:22669257] +synonym: "transport protein particle" EXACT [] +synonym: "transport protein particle complex" EXACT [GOC:bhm] +synonym: "TRAPP1" NARROW [GOC:vw] +synonym: "TRAPP2" NARROW [GOC:vw] +xref: Wikipedia:TRAPP_complex +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030009 +name: obsolete complement factor H activity +namespace: molecular_function +def: "OBSOLETE. A cofactor for the serine protease complement factor I." [ISBN:0198547684] +comment: This term was made obsolete because it represents a gene product. +synonym: "complement factor H activity" EXACT [] +is_obsolete: true +consider: GO:0006956 + +[Term] +id: GO:0030010 +name: establishment of cell polarity +namespace: biological_process +alt_id: GO:0000283 +alt_id: GO:0030468 +def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah] +synonym: "bud site selection/establishment of cell polarity" NARROW [] +synonym: "cell polarization" EXACT [] +is_a: GO:0007163 ! establishment or maintenance of cell polarity + +[Term] +id: GO:0030011 +name: maintenance of cell polarity +namespace: biological_process +alt_id: GO:0030013 +alt_id: GO:0030469 +def: "The maintenance of established anisotropic intracellular organization or cell growth patterns." [GOC:mah] +is_a: GO:0007163 ! establishment or maintenance of cell polarity + +[Term] +id: GO:0030014 +name: CCR4-NOT complex +namespace: cellular_component +def: "The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8." [GOC:sart, PMID:11113136, PMID:11239395, PMID:22785621, PMID:30601114] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030015 +name: CCR4-NOT core complex +namespace: cellular_component +def: "The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p." [GOC:sart, PMID:11113136] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030014 ! CCR4-NOT complex + +[Term] +id: GO:0030016 +name: myofibril +namespace: cellular_component +def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] +synonym: "striated muscle fiber" RELATED [] +synonym: "striated muscle fibre" RELATED [] +xref: Wikipedia:Myofibril +is_a: GO:0043292 ! contractile fiber + +[Term] +id: GO:0030017 +name: sarcomere +namespace: cellular_component +def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] +xref: Wikipedia:Sarcomere +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030016 ! myofibril + +[Term] +id: GO:0030018 +name: Z disc +namespace: cellular_component +def: "Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached." [GOC:mtg_muscle, ISBN:0815316194] +synonym: "Z band" EXACT [] +synonym: "Z disk" EXACT [] +synonym: "Z line" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031674 ! I band + +[Term] +id: GO:0030019 +name: obsolete tryptase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin." [EC:3.4.21.59] +comment: This term was made obsolete because it represents a gene product. +synonym: "lung tryptase activity" NARROW [EC:3.4.21.59] +synonym: "mast cell neutral proteinase activity" EXACT [EC:3.4.21.59] +synonym: "mast cell protease II activity" NARROW [EC:3.4.21.59] +synonym: "mast cell proteinase II" RELATED [EC:3.4.21.59] +synonym: "mast cell serine proteinase II" RELATED [EC:3.4.21.59] +synonym: "mast cell serine proteinase tryptase activity" EXACT [EC:3.4.21.59] +synonym: "mast cell tryptase activity" NARROW [EC:3.4.21.59] +synonym: "pituitary tryptase activity" NARROW [EC:3.4.21.59] +synonym: "rat mast cell protease II" RELATED [EC:3.4.21.59] +synonym: "skin tryptase activity" NARROW [EC:3.4.21.59] +synonym: "tryptase activity" EXACT [] +synonym: "tryptase M" RELATED [EC:3.4.21.59] +xref: EC:3.4.21.59 +xref: MetaCyc:3.4.21.59-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0030020 +name: extracellular matrix structural constituent conferring tensile strength +namespace: molecular_function +def: "A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress." [GOC:mah, ISBN:0815316194] +comment: Extracellular matrix collagen proteins may be annotated to this term. PMID:29632050, PMID:24443019 +synonym: "core extracellular matrix" BROAD [] +synonym: "core matrisome" BROAD [] +is_a: GO:0005201 ! extracellular matrix structural constituent + +[Term] +id: GO:0030021 +name: extracellular matrix structural constituent conferring compression resistance +namespace: molecular_function +def: "A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan." [GOC:mah, ISBN:0815316194] +comment: Extracellular matrix proteoglycans may be annotated to this term. PMID:8346704 +synonym: "core extracellular matrix" BROAD [] +synonym: "core matrisome" BROAD [] +is_a: GO:0005201 ! extracellular matrix structural constituent + +[Term] +id: GO:0030022 +name: obsolete adhesive extracellular matrix constituent +namespace: molecular_function +def: "OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix." [GOC:mah, ISBN:0815316194] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "adhesive extracellular matrix constituent" EXACT [] +is_obsolete: true +consider: GO:0030674 +consider: GO:0031012 +consider: GO:0050839 +consider: GO:0050840 + +[Term] +id: GO:0030023 +name: extracellular matrix constituent conferring elasticity +namespace: molecular_function +def: "A component of the extracellular matrix that enables the matrix to recoil after transient stretching." [GOC:mah, ISBN:0815316194] +comment: Extracellular matrix elastin proteins may be annotated to this term. PMID:27009176, PMID:24443019 +synonym: "core extracellular matrix" BROAD [] +synonym: "core matrisome" BROAD [] +synonym: "elastin" RELATED [] +is_a: GO:0005201 ! extracellular matrix structural constituent +is_a: GO:0097493 ! structural molecule activity conferring elasticity + +[Term] +id: GO:0030026 +name: cellular manganese ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell." [GOC:mah] +synonym: "manganese homeostasis" BROAD [] +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0055071 ! manganese ion homeostasis + +[Term] +id: GO:0030027 +name: lamellipodium +namespace: cellular_component +def: "A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments." [ISBN:0815316194] +xref: Wikipedia:Lamellipodia +is_a: GO:0120025 ! plasma membrane bounded cell projection +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0030029 +name: actin filament-based process +namespace: biological_process +def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah] +synonym: "microfilament-based process" RELATED [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0030030 +name: cell projection organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] +synonym: "cell projection organisation" EXACT [] +synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] +synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0030031 +name: cell projection assembly +namespace: biological_process +def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] +synonym: "cell projection biogenesis" RELATED [GOC:mah] +synonym: "formation of a cell surface projection" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0030030 ! cell projection organization + +[Term] +id: GO:0030032 +name: lamellipodium assembly +namespace: biological_process +def: "Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:mah, ISBN:0815316194] +synonym: "lamellipodium biogenesis" RELATED [GOC:mah] +synonym: "lamellipodium biosynthesis" EXACT [] +synonym: "lamellipodium formation" EXACT [] +is_a: GO:0097581 ! lamellipodium organization +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0030033 +name: microvillus assembly +namespace: biological_process +def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194] +synonym: "microvillus biogenesis" RELATED [GOC:mah] +is_a: GO:0032528 ! microvillus organization +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0030034 +name: microvillar actin bundle assembly +namespace: biological_process +def: "Assembly of the parallel bundle of actin filaments at the core of a microvillus." [GOC:mah] +is_a: GO:0030046 ! parallel actin filament bundle assembly +relationship: part_of GO:0030033 ! microvillus assembly + +[Term] +id: GO:0030035 +name: microspike assembly +namespace: biological_process +def: "Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell." [ISBN:0815316194, PMID:11429692, PMID:12153987, PMID:19095735] +comment: Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. For the assembly of filopodia, use 'filopodium assembly ; GO:0046847'. +synonym: "microspike biogenesis" RELATED [GOC:mah] +synonym: "microspike biosynthesis" EXACT [] +synonym: "microspike formation" EXACT [] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0030036 +name: actin cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_drosophila +subset: goslim_pombe +synonym: "actin cytoskeleton organisation" EXACT [] +synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] +synonym: "actin modulating activity" RELATED [] +is_a: GO:0007010 ! cytoskeleton organization +is_a: GO:0030029 ! actin filament-based process + +[Term] +id: GO:0030037 +name: actin filament reorganization involved in cell cycle +namespace: biological_process +def: "The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs." [GOC:mah] +synonym: "actin filament reorganisation involved in cell cycle" EXACT [GOC:mah] +synonym: "actin filament reorganization during cell cycle" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0090527 ! actin filament reorganization +intersection_of: GO:0090527 ! actin filament reorganization +intersection_of: part_of GO:0007049 ! cell cycle + +[Term] +id: GO:0030038 +name: contractile actin filament bundle assembly +namespace: biological_process +def: "Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle." [GOC:mah, ISBN:0815316194] +is_a: GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0030039 +name: obsolete DNA unwinding factor +namespace: molecular_function +alt_id: GO:0017152 +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it does not represent a true molecular function. +synonym: "DNA unwinding factor" EXACT [] +is_obsolete: true +replaced_by: GO:0006268 + +[Term] +id: GO:0030041 +name: actin filament polymerization +namespace: biological_process +def: "Assembly of actin filaments by the addition of actin monomers to a filament." [GOC:mah] +synonym: "actin polymerization" EXACT [] +synonym: "actin polymerizing activity" RELATED [] +is_a: GO:0008154 ! actin polymerization or depolymerization +is_a: GO:0051258 ! protein polymerization + +[Term] +id: GO:0030042 +name: actin filament depolymerization +namespace: biological_process +def: "Disassembly of actin filaments by the removal of actin monomers from a filament." [GOC:mah] +synonym: "actin depolymerization" EXACT [] +synonym: "actin depolymerizing activity" RELATED [] +is_a: GO:0008154 ! actin polymerization or depolymerization +is_a: GO:0051261 ! protein depolymerization + +[Term] +id: GO:0030043 +name: actin filament fragmentation +namespace: biological_process +def: "The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins." [GOC:mah, ISBN:0815316194] +is_a: GO:0030042 ! actin filament depolymerization + +[Term] +id: GO:0030046 +name: parallel actin filament bundle assembly +namespace: biological_process +def: "Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity." [GOC:mah, ISBN:0815316194] +is_a: GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0030047 +name: actin modification +namespace: biological_process +alt_id: GO:0007013 +def: "Covalent modification of an actin molecule." [GOC:mah] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0030036 ! actin cytoskeleton organization + +[Term] +id: GO:0030048 +name: actin filament-based movement +namespace: biological_process +def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah] +is_a: GO:0006928 ! movement of cell or subcellular component +is_a: GO:0030029 ! actin filament-based process + +[Term] +id: GO:0030049 +name: muscle filament sliding +namespace: biological_process +def: "The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated." [GOC:mah, GOC:mtg_muscle, ISBN:0815316194] +is_a: GO:0033275 ! actin-myosin filament sliding +relationship: part_of GO:0006936 ! muscle contraction + +[Term] +id: GO:0030050 +name: vesicle transport along actin filament +namespace: biological_process +def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah] +is_a: GO:0030048 ! actin filament-based movement +is_a: GO:0099515 ! actin filament-based transport +is_a: GO:0099518 ! vesicle cytoskeletal trafficking + +[Term] +id: GO:0030051 +name: obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase +namespace: molecular_function +def: "OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0))." [EC:5.2.1.8, ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product and not a function. +synonym: "FK506 binding protein" RELATED [] +synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" EXACT [] +synonym: "FKBP" RELATED [] +is_obsolete: true +consider: GO:0003755 +consider: GO:0005528 + +[Term] +id: GO:0030052 +name: obsolete parvulin +namespace: molecular_function +def: "OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin." [ISBN:0198506732] +comment: This term was made obsolete because it describes a gene product. +synonym: "parvulin" EXACT [] +is_obsolete: true +replaced_by: GO:0003755 + +[Term] +id: GO:0030053 +name: obsolete immunophilin +namespace: molecular_function +def: "OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin." [ISBN:0198506732] +comment: This term was made obsolete because it does not represent a molecular function. +synonym: "immunophilin" EXACT [] +is_obsolete: true +consider: GO:0003755 + +[Term] +id: GO:0030054 +name: cell junction +namespace: cellular_component +def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264] +subset: goslim_agr +subset: goslim_drosophila +subset: goslim_flybase_ribbon +xref: Wikipedia:Cell_junction +is_a: GO:0110165 ! cellular anatomical entity +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030055 +name: cell-substrate junction +namespace: cellular_component +def: "A cell junction that forms a connection between a cell and the extracellular matrix." [GOC:aruk, GOC:bc, GOC:hb, GOC:mah, PMID:10419689, PMID:1643657, PMID:16805308, PMID:26923917, PMID:8314002] +synonym: "cell-matrix junction" EXACT [] +is_a: GO:0070161 ! anchoring junction + +[Term] +id: GO:0030056 +name: hemidesmosome +namespace: cellular_component +def: "A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces." [GOC:kmv, ISBN:0815316208, PMID:20205195] +synonym: "epidermal attachment structure" NARROW [GOC:kmv] +synonym: "fibrous organelle" NARROW [GOC:kmv, PMID:20205195] +synonym: "hemi-adherens junction" RELATED [] +synonym: "trans-epithelial attachment" NARROW [GOC:kmv, PMID:20205195] +xref: Wikipedia:Hemidesmosome +is_a: GO:0030055 ! cell-substrate junction + +[Term] +id: GO:0030057 +name: desmosome +namespace: cellular_component +def: "A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181] +synonym: "macula adherens" EXACT [] +synonym: "spot desmosome" EXACT [] +xref: Wikipedia:Desmosome +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0030058 +name: amine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor." [EC:1.4.9.1] +synonym: "amine: (acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.9.1] +synonym: "MADH activity" EXACT [EC:1.4.9.1] +synonym: "methylamine dehydrogenase activity" RELATED [EC:1.4.9.1] +synonym: "primary-amine dehydrogenase activity" BROAD [EC:1.4.9.1] +synonym: "primary-amine:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.9.1] +synonym: "primary-amine:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.9.1] +xref: EC:1.4.9.1 +xref: MetaCyc:AMINE-DEHYDROGENASE-RXN +xref: RHEA:30207 +xref: UM-BBD_enzymeID:e0058 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0030059 +name: aralkylamine dehydrogenase (azurin) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + arCH(2)NH(2) + 2 azurin = 2 reduced azurin + ArCHO + NH(3). The symbol arCH(2)NH(2) represents an aralkylamine and ArCHO is an aryl aldehyde." [EC:1.4.9.2] +synonym: "aralkylamine:(azurin) oxidoreductase (deaminating) activity" EXACT [EC:1.4.9.2] +synonym: "aromatic amine dehydrogenase (azurin) activity" EXACT [EC:1.4.9.2] +synonym: "arylamine dehydrogenase activity" BROAD [EC:1.4.9.2] +synonym: "dehydrogenase, arylamine (azurin) activity" EXACT [EC:1.4.9.2] +synonym: "tyramine dehydrogenase (azurin) activity" NARROW [EC:1.4.9.2] +xref: EC:1.4.9.2 +xref: MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN +is_a: GO:0052877 ! oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor + +[Term] +id: GO:0030060 +name: L-malate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+." [EC:1.1.1.37] +synonym: "(S)-malate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.37] +synonym: "L-malate-NAD+ oxidoreductase activity" EXACT [EC:1.1.1.37] +synonym: "malate (NAD) dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "malic acid dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "malic dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "MDH" RELATED [EC:1.1.1.37] +synonym: "NAD-dependent malate dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "NAD-dependent malic dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "NAD-L-malate dehydrogenase activity" EXACT [] +synonym: "NAD-linked malate dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "NAD-malate dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "NAD-malic dehydrogenase activity" EXACT [EC:1.1.1.37] +synonym: "NAD-specific malate dehydrogenase activity" EXACT [EC:1.1.1.37] +xref: EC:1.1.1.37 +xref: MetaCyc:MALATE-DEH-RXN +xref: Reactome:R-HSA-198508 "malate + NAD+ <=> oxaloacetate + NADH + H+" +xref: Reactome:R-HSA-70979 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+" +xref: Reactome:R-HSA-71783 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+" +xref: RHEA:21432 +is_a: GO:0016615 ! malate dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0030061 +name: mitochondrial crista +namespace: cellular_component +def: "Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria." [ISBN:0198506732] +comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. +synonym: "cristae" BROAD [NIF_Subcellular:sao333328131] +synonym: "mitochondrial cristae" EXACT [] +xref: NIF_Subcellular:sao333328131 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0030062 +name: mitochondrial tricarboxylic acid cycle enzyme complex +namespace: cellular_component +def: "Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu] +synonym: "TCA cycle enzyme complex" BROAD [] +is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0045239 ! tricarboxylic acid cycle enzyme complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0030063 +name: obsolete murein sacculus +namespace: cellular_component +def: "OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall." [GOC:mah, PMID:9529891] +comment: This term was made obsolete because it was defined inaccurately. +synonym: "murein sacculus" EXACT [] +synonym: "peptidoglycan layer" EXACT [] +is_obsolete: true +consider: GO:0009276 + +[Term] +id: GO:0030064 +name: obsolete cell wall inner membrane +namespace: cellular_component +def: "OBSOLETE. The peptidoglycan layer of the cell wall of Gram-negative bacteria." [ISBN:0135712254] +comment: This term was made obsolete because it was defined inaccurately. +synonym: "cell wall inner membrane" EXACT [] +is_obsolete: true +consider: GO:0009276 + +[Term] +id: GO:0030066 +name: obsolete cytochrome b6 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytochrome b-563" RELATED [] +synonym: "cytochrome b6" EXACT [] +is_obsolete: true +replaced_by: GO:0045158 + +[Term] +id: GO:0030067 +name: obsolete respiratory chain cytochrome b6 +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "respiratory chain cytochrome b6" EXACT [] +is_obsolete: true +consider: GO:0009055 + +[Term] +id: GO:0030068 +name: obsolete lytic viral life cycle +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because more specific terms were created. +synonym: "lytic viral life cycle" EXACT [] +is_obsolete: true +consider: GO:0019058 +consider: GO:0044659 + +[Term] +id: GO:0030070 +name: insulin processing +namespace: biological_process +def: "The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges." [ISBN:0198506732] +is_a: GO:0016486 ! peptide hormone processing +is_a: GO:1901142 ! insulin metabolic process + +[Term] +id: GO:0030071 +name: regulation of mitotic metaphase/anaphase transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." [GOC:mah] +is_a: GO:0010965 ! regulation of mitotic sister chromatid separation +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +is_a: GO:1902099 ! regulation of metaphase/anaphase transition of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle +relationship: regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle + +[Term] +id: GO:0030072 +name: peptide hormone secretion +namespace: biological_process +def: "The regulated release of a peptide hormone from a cell." [GOC:mah] +is_a: GO:0002790 ! peptide secretion +is_a: GO:0046879 ! hormone secretion + +[Term] +id: GO:0030073 +name: insulin secretion +namespace: biological_process +def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] +is_a: GO:0009306 ! protein secretion +is_a: GO:0030072 ! peptide hormone secretion +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045 xsd:anyURI + +[Term] +id: GO:0030074 +name: obsolete thylakoid (sensu Proteobacteria) +namespace: cellular_component +def: "OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224)." [GOC:mah] +comment: This term was made obsolete because thylakoids are not found in organisms of the Phylum Proteobacteria. +synonym: "thylakoid (sensu Proteobacteria)" EXACT [] +is_obsolete: true +consider: GO:0042716 + +[Term] +id: GO:0030075 +name: bacterial thylakoid +namespace: cellular_component +def: "A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria." [GOC:mah, GOC:mtg_sensu] +synonym: "plasma membrane-derived thylakoid" EXACT [] +is_a: GO:0009579 ! thylakoid +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0030076 +name: light-harvesting complex +namespace: cellular_component +def: "A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center." [GOC:lr] +subset: goslim_pir +synonym: "antenna complex" RELATED [] +xref: Wikipedia:Light-harvesting_complex +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030077 +name: plasma membrane light-harvesting complex +namespace: cellular_component +def: "A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0030076 ! light-harvesting complex +relationship: part_of GO:0031410 ! cytoplasmic vesicle +relationship: part_of GO:0042716 ! plasma membrane-derived chromatophore + +[Term] +id: GO:0030078 +name: light-harvesting complex, core complex +namespace: cellular_component +def: "Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria." [GOC:lr] +is_a: GO:0030077 ! plasma membrane light-harvesting complex + +[Term] +id: GO:0030079 +name: light-harvesting complex, peripheral complex +namespace: cellular_component +def: "Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center." [GOC:lr] +is_a: GO:0030077 ! plasma membrane light-harvesting complex + +[Term] +id: GO:0030080 +name: B875 antenna complex +namespace: cellular_component +def: "Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm." [GOC:kd] +synonym: "LH1 complex" EXACT [] +synonym: "light harvesting complex I" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030078 ! light-harvesting complex, core complex + +[Term] +id: GO:0030081 +name: B800-820 antenna complex +namespace: cellular_component +def: "Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex." [GOC:kd, GOC:lr] +synonym: "LH3 complex" EXACT [] +synonym: "light harvesting complex III" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030079 ! light-harvesting complex, peripheral complex + +[Term] +id: GO:0030082 +name: B800-850 antenna complex +namespace: cellular_component +def: "Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex." [GOC:kd, GOC:lr] +synonym: "LH2 complex" EXACT [] +synonym: "light harvesting complex II" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030079 ! light-harvesting complex, peripheral complex + +[Term] +id: GO:0030083 +name: PSI associated light-harvesting complex I, LHCIa subcomplex +namespace: cellular_component +def: "A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm." [PMID:8825475] +is_a: GO:0009518 ! PSI associated light-harvesting complex I + +[Term] +id: GO:0030084 +name: PSI associated light-harvesting complex I, LHCIb subcomplex +namespace: cellular_component +def: "A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm." [PMID:8825475] +is_a: GO:0009518 ! PSI associated light-harvesting complex I + +[Term] +id: GO:0030085 +name: PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex +namespace: cellular_component +def: "A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides." [PMID:8825475] +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +relationship: part_of GO:0009656 ! PSII associated light-harvesting complex II, peripheral complex + +[Term] +id: GO:0030086 +name: obsolete PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the 'complex' it refers to contains only one gene product. +synonym: "PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex" EXACT [] +is_obsolete: true +replaced_by: GO:0009655 + +[Term] +id: GO:0030087 +name: obsolete PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the 'complex' it refers to contains only one gene product. +synonym: "PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex" EXACT [] +is_obsolete: true +replaced_by: GO:0009655 + +[Term] +id: GO:0030088 +name: obsolete PSII associated light-harvesting complex II, core complex, LHCIId subcomplex +namespace: cellular_component +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because the 'complex' it refers to contains only one gene product. +synonym: "PSII associated light-harvesting complex II, core complex, LHCIId subcomplex" EXACT [] +is_obsolete: true +replaced_by: GO:0009655 + +[Term] +id: GO:0030089 +name: phycobilisome +namespace: cellular_component +def: "Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II." [GOC:jl, PMID:11734882, Wikipedia:Phycobilisome] +xref: Wikipedia:Phycobilisome +is_a: GO:0030076 ! light-harvesting complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0042651 ! thylakoid membrane + +[Term] +id: GO:0030091 +name: protein repair +namespace: biological_process +def: "The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues." [GOC:mlg] +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0030092 +name: obsolete regulation of flagellum assembly +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the formation of a flagellum." [GOC:go_curators] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "regulation of flagella assembly" RELATED [GOC:mah] +synonym: "regulation of flagella biogenesis" RELATED [] +synonym: "regulation of flagellum assembly" EXACT [] +synonym: "regulation of flagellum biogenesis" RELATED [GOC:mah] +is_obsolete: true +consider: GO:1902017 +consider: GO:1902208 + +[Term] +id: GO:0030093 +name: chloroplast photosystem I +namespace: cellular_component +def: "Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana." [GOC:jid, GOC:mtg_sensu] +is_a: GO:0009522 ! photosystem I +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +intersection_of: GO:0009522 ! photosystem I +intersection_of: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0030094 +name: plasma membrane-derived photosystem I +namespace: cellular_component +def: "A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species." [GOC:jid, GOC:mtg_sensu] +synonym: "plasma membrane photosystem I" EXACT [] +is_a: GO:0009522 ! photosystem I +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0009522 ! photosystem I +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0030075 ! bacterial thylakoid + +[Term] +id: GO:0030095 +name: chloroplast photosystem II +namespace: cellular_component +def: "An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone." [GOC:jid, GOC:mtg_sensu] +is_a: GO:0009523 ! photosystem II +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +intersection_of: GO:0009523 ! photosystem II +intersection_of: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0030096 +name: plasma membrane-derived thylakoid photosystem II +namespace: cellular_component +def: "A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone." [GOC:jid, GOC:mtg_sensu] +synonym: "plasma membrane photosystem II" EXACT [] +is_a: GO:0009523 ! photosystem II +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0009523 ! photosystem II +intersection_of: part_of GO:0030075 ! bacterial thylakoid +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0030075 ! bacterial thylakoid + +[Term] +id: GO:0030097 +name: hemopoiesis +namespace: biological_process +def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] +synonym: "blood cell biosynthesis" EXACT [] +synonym: "blood cell formation" EXACT [] +synonym: "haemopoiesis" EXACT [] +synonym: "hematopoiesis" EXACT [] +xref: Wikipedia:Haematopoiesis +is_a: GO:0048534 ! hematopoietic or lymphoid organ development + +[Term] +id: GO:0030098 +name: lymphocyte differentiation +namespace: biological_process +alt_id: GO:0046650 +def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "lymphocyte cell differentiation" EXACT [] +synonym: "lymphocyte development" RELATED [GOC:add] +synonym: "lymphocytic blood cell differentiation" EXACT [] +is_a: GO:0002521 ! leukocyte differentiation +is_a: GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0030099 +name: myeloid cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030097 ! hemopoiesis + +[Term] +id: GO:0030100 +name: regulation of endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006897 ! endocytosis +relationship: regulates GO:0006897 ! endocytosis + +[Term] +id: GO:0030101 +name: natural killer cell activation +namespace: biological_process +def: "The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] +synonym: "NK cell activation" EXACT [] +is_a: GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0030103 +name: vasopressin secretion +namespace: biological_process +def: "The regulated release of vasopressin from secretory granules into the blood." [GOC:mah] +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0030104 +name: water homeostasis +namespace: biological_process +alt_id: GO:0018987 +def: "Any process involved in the maintenance of an internal steady state of water within an organism or cell." [GOC:dph, GOC:mah, GOC:tb] +synonym: "osmoregulation" RELATED [] +synonym: "regulation of osmotic pressure" EXACT [] +xref: Wikipedia:Osmoregulation +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0030105 +name: obsolete anaphylaxis +namespace: biological_process +def: "OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances." [ISBN:0198506732] +comment: This term was made obsolete because it represents a an abnormal process that is harmful to the organism. +synonym: "anaphylaxis" EXACT [] +is_obsolete: true +consider: GO:0006955 + +[Term] +id: GO:0030106 +name: obsolete MHC class I receptor activity +namespace: molecular_function +def: "OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells)." [ISBN:081533642X, ISBN:0879694971] +comment: This term was made obsolete because the definition is ambiguous and contains incorrect information. To update annotations of gene products that act as receptors for MHC class I protein complexes, use the molecular function term 'MHC class I receptor activity ; GO:0032393'; to update annotations of gene products which are components of MHC class I protein complexes, use the cellular component term 'MHC class I protein complex ; GO:0042612'. +synonym: "class I major histocompatibility complex antigen" RELATED [] +synonym: "major histocompatibility complex class I receptor" EXACT [] +synonym: "MHC class I receptor activity" EXACT [] +is_obsolete: true +consider: GO:0032393 +consider: GO:0042612 + +[Term] +id: GO:0030107 +name: HLA-A specific inhibitory MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] +is_a: GO:0032396 ! inhibitory MHC class I receptor activity + +[Term] +id: GO:0030108 +name: HLA-A specific activating MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] +is_a: GO:0032397 ! activating MHC class I receptor activity + +[Term] +id: GO:0030109 +name: HLA-B specific inhibitory MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] +is_a: GO:0032396 ! inhibitory MHC class I receptor activity + +[Term] +id: GO:0030110 +name: HLA-C specific inhibitory MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] +is_a: GO:0032396 ! inhibitory MHC class I receptor activity + +[Term] +id: GO:0030111 +name: regulation of Wnt signaling pathway +namespace: biological_process +alt_id: GO:0008590 +def: "Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of frizzled signaling pathway" EXACT [] +synonym: "regulation of frizzled signalling pathway" EXACT [] +synonym: "regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway" EXACT [] +synonym: "regulation of Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016055 ! Wnt signaling pathway +relationship: regulates GO:0016055 ! Wnt signaling pathway + +[Term] +id: GO:0030112 +name: glycocalyx +namespace: cellular_component +def: "A viscous, carbohydrate rich layer at the outermost periphery of a cell." [GOC:mlg, ISBN:0815316208] +subset: goslim_pir +synonym: "cell capsule" EXACT [VZ:3896] +xref: Wikipedia:Glycocalyx +is_a: GO:0030312 ! external encapsulating structure +relationship: part_of GO:0030313 ! cell envelope + +[Term] +id: GO:0030114 +name: slime layer +namespace: cellular_component +def: "A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids." [GOC:mlg, Wikipedia:Slime_layer] +xref: Wikipedia:Slime_layer +is_a: GO:0030112 ! glycocalyx + +[Term] +id: GO:0030115 +name: S-layer +namespace: cellular_component +def: "A crystalline protein layer surrounding some bacteria." [GOC:mlg, ISBN:0815108893] +subset: goslim_pir +xref: Wikipedia:S-layer +is_a: GO:0030312 ! external encapsulating structure + +[Term] +id: GO:0030116 +name: glial cell-derived neurotrophic factor receptor binding +namespace: molecular_function +def: "A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors." [GOC:vw, PMID:11476867] +synonym: "glial cell line-derived neurotrophic factor receptor binding" RELATED [] +synonym: "glial cell line-derived neurotrophic factor receptor ligand" NARROW [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0030117 +name: membrane coat +namespace: cellular_component +def: "Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules." [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0048475 ! coated membrane + +[Term] +id: GO:0030118 +name: clathrin coat +namespace: cellular_component +alt_id: GO:0016190 +def: "A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes." [GOC:mah, PMID:11252894, PMID:9531549] +synonym: "clathrin cage" EXACT [] +xref: NIF_Subcellular:sao879919129 +xref: Wikipedia:Clathrin +is_a: GO:0030117 ! membrane coat + +[Term] +id: GO:0030119 +name: AP-type membrane coat adaptor complex +namespace: cellular_component +def: "Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa)." [GOC:mah, PMID:10611976, PMID:15473838] +subset: goslim_pir +synonym: "clathrin adaptor" RELATED [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030117 ! membrane coat + +[Term] +id: GO:0030120 +name: vesicle coat +namespace: cellular_component +def: "A membrane coat found on a coated vesicle." [GOC:mah] +xref: NIF_Subcellular:sao1177708494 +is_a: GO:0030117 ! membrane coat +relationship: part_of GO:0030662 ! coated vesicle membrane + +[Term] +id: GO:0030121 +name: AP-1 adaptor complex +namespace: cellular_component +def: "A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C)." [GOC:mah, PMID:10611976, PMID:21097499] +synonym: "HA1" EXACT [] +synonym: "HA1 clathrin adaptor" EXACT [] +is_a: GO:0030131 ! clathrin adaptor complex +relationship: part_of GO:0030130 ! clathrin coat of trans-Golgi network vesicle + +[Term] +id: GO:0030122 +name: AP-2 adaptor complex +namespace: cellular_component +def: "A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)." [GOC:mah, PMID:10611976, PMID:21097499, PMID:22022230, PMID:24322426] +synonym: "HA2" EXACT [] +synonym: "HA2 clathrin adaptor" EXACT [] +is_a: GO:0030131 ! clathrin adaptor complex +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0030128 ! clathrin coat of endocytic vesicle +relationship: part_of GO:0030132 ! clathrin coat of coated pit + +[Term] +id: GO:0030123 +name: AP-3 adaptor complex +namespace: cellular_component +def: "A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B)." [GOC:mah, PMID:10611976, PMID:21097499] +is_a: GO:0030119 ! AP-type membrane coat adaptor complex + +[Term] +id: GO:0030124 +name: AP-4 adaptor complex +namespace: cellular_component +def: "An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo." [GOC:mah, PMID:10611976] +is_a: GO:0030119 ! AP-type membrane coat adaptor complex + +[Term] +id: GO:0030125 +name: clathrin vesicle coat +namespace: cellular_component +def: "A clathrin coat found on a vesicle." [GOC:mah] +is_a: GO:0030118 ! clathrin coat +is_a: GO:0030120 ! vesicle coat +relationship: part_of GO:0030665 ! clathrin-coated vesicle membrane + +[Term] +id: GO:0030126 +name: COPI vesicle coat +namespace: cellular_component +alt_id: GO:0017167 +def: "One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state." [GOC:mah, PMID:11252894] +synonym: "coatomer" EXACT [] +is_a: GO:0030120 ! vesicle coat +relationship: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0030663 ! COPI-coated vesicle membrane + +[Term] +id: GO:0030127 +name: COPII vesicle coat +namespace: cellular_component +def: "One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:tb, PMID:11252894] +is_a: GO:0030120 ! vesicle coat +relationship: part_of GO:0012507 ! ER to Golgi transport vesicle membrane + +[Term] +id: GO:0030128 +name: clathrin coat of endocytic vesicle +namespace: cellular_component +def: "A clathrin coat found on an endocytic vesicle." [GOC:mah] +synonym: "clathrin coat of endocytotic vesicle" EXACT [] +is_a: GO:0030125 ! clathrin vesicle coat +intersection_of: GO:0030118 ! clathrin coat +intersection_of: part_of GO:0030139 ! endocytic vesicle +relationship: part_of GO:0030669 ! clathrin-coated endocytic vesicle membrane + +[Term] +id: GO:0030129 +name: clathrin coat of synaptic vesicle +namespace: cellular_component +def: "A clathrin coat found on a synaptic vesicle." [GOC:mah] +is_a: GO:0030125 ! clathrin vesicle coat +intersection_of: GO:0030118 ! clathrin coat +intersection_of: part_of GO:0008021 ! synaptic vesicle +relationship: part_of GO:0030672 ! synaptic vesicle membrane + +[Term] +id: GO:0030130 +name: clathrin coat of trans-Golgi network vesicle +namespace: cellular_component +def: "A clathrin coat found on a vesicle of the trans-Golgi network." [GOC:mah] +synonym: "clathrin coat of TGN vesicle" EXACT [] +is_a: GO:0030125 ! clathrin vesicle coat +relationship: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0012510 ! trans-Golgi network transport vesicle membrane + +[Term] +id: GO:0030131 +name: clathrin adaptor complex +namespace: cellular_component +def: "A membrane coat adaptor complex that links clathrin to a membrane." [GOC:mah] +is_a: GO:0030119 ! AP-type membrane coat adaptor complex +relationship: part_of GO:0030118 ! clathrin coat + +[Term] +id: GO:0030132 +name: clathrin coat of coated pit +namespace: cellular_component +def: "The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex." [GOC:mah] +is_a: GO:0030118 ! clathrin coat +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0030118 ! clathrin coat +intersection_of: part_of GO:0005905 ! clathrin-coated pit +relationship: part_of GO:0005905 ! clathrin-coated pit + +[Term] +id: GO:0030133 +name: transport vesicle +namespace: cellular_component +def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157] +comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. +synonym: "constitutive secretory pathway transport vesicle" EXACT [] +synonym: "Golgi to vacuole transport vesicle" NARROW [] +synonym: "Golgi-vacuole transport vesicle" NARROW [] +synonym: "secretory vesicle" RELATED [] +xref: NIF_Subcellular:sao885490876 +is_a: GO:0031410 ! cytoplasmic vesicle +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0030134 +name: COPII-coated ER to Golgi transport vesicle +namespace: cellular_component +alt_id: GO:0030138 +alt_id: GO:0140045 +def: "A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport)." [PMID:11252894, PMID:17499046, PMID:22160157, PMID:8004676, Wikipedia:COPII] +synonym: "COPII vesicle" RELATED [] +synonym: "COPII-associated ER to Golgi transport vesicle" EXACT [] +synonym: "COPII-associated vesicle" EXACT [] +synonym: "COPII-coated vesicle" EXACT [] +synonym: "endoplasmic reticulum to Golgi transport vesicle" RELATED [] +synonym: "endoplasmic reticulum-Golgi transport vesicle" RELATED [] +synonym: "ER to Golgi constitutive secretory pathway transport vesicle" RELATED [] +synonym: "ER to Golgi transport vesicle" RELATED [] +synonym: "ER-Golgi transport vesicle" RELATED [] +is_a: GO:0005798 ! Golgi-associated vesicle +is_a: GO:0030135 ! coated vesicle +created_by: pg +creation_date: 2017-06-22T16:26:57Z + +[Term] +id: GO:0030135 +name: coated vesicle +namespace: cellular_component +alt_id: GO:0005909 +def: "Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins." [ISBN:0815316194] +subset: goslim_drosophila +xref: NIF_Subcellular:sao1985096626 +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0030136 +name: clathrin-coated vesicle +namespace: cellular_component +def: "A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes." [GOC:mah, PMID:11252894] +xref: NIF_Subcellular:sao148845161 +is_a: GO:0030135 ! coated vesicle + +[Term] +id: GO:0030137 +name: COPI-coated vesicle +namespace: cellular_component +def: "A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport." [GOC:mah, PMID:11252894] +synonym: "coatomer" RELATED [] +is_a: GO:0005798 ! Golgi-associated vesicle +is_a: GO:0030135 ! coated vesicle + +[Term] +id: GO:0030139 +name: endocytic vesicle +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting." [GOC:go_curators, PMID:19696797] +synonym: "endocytotic transport vesicle" EXACT [] +synonym: "endocytotic vesicle" EXACT [] +xref: NIF_Subcellular:sao1362520468 +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0030140 +name: trans-Golgi network transport vesicle +namespace: cellular_component +def: "A vesicle that mediates transport between the trans-Golgi network and other parts of the cell." [GOC:mah] +synonym: "TGN transport vesicle" EXACT [] +synonym: "trans-Golgi network constitutive secretory pathway transport vesicle" EXACT [] +is_a: GO:0005798 ! Golgi-associated vesicle +is_a: GO:0030133 ! transport vesicle +is_a: GO:0030136 ! clathrin-coated vesicle + +[Term] +id: GO:0030141 +name: secretory granule +namespace: cellular_component +def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732] +comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'. +synonym: "secretory vesicle" BROAD [] +is_a: GO:0099503 ! secretory vesicle +relationship: part_of GO:0012505 ! endomembrane system +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0030142 +name: COPI-coated Golgi to ER transport vesicle +namespace: cellular_component +def: "A vesicle that mediates transport from the Golgi to the endoplasmic reticulum." [GOC:mah, PMID:22160157] +synonym: "Golgi to endoplasmic reticulum transport vesicle" EXACT [] +synonym: "Golgi to ER constitutive secretory pathway transport vesicle" EXACT [] +synonym: "Golgi-endoplasmic reticulum transport vesicle" EXACT [] +synonym: "Golgi-ER transport vesicle" EXACT [] +synonym: "retrograde transport vesicle" EXACT [PMID:22160157] +is_a: GO:0030133 ! transport vesicle +is_a: GO:0030137 ! COPI-coated vesicle + +[Term] +id: GO:0030143 +name: COPI-coated inter-Golgi transport vesicle +namespace: cellular_component +alt_id: GO:0005807 +def: "A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack)." [GOC:mah] +synonym: "inter-Golgi transport constitutive secretory pathway transport vesicle" EXACT [] +xref: NIF_Subcellular:sao1382918459 +is_a: GO:0030133 ! transport vesicle +is_a: GO:0030137 ! COPI-coated vesicle + +[Term] +id: GO:0030144 +name: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors." [EC:2.4.1.155] +synonym: "alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] +synonym: "GnTV activity" EXACT [EC:2.4.1.155] +synonym: "N-acetylglucosaminyltransferase V activity" RELATED [EC:2.4.1.155] +synonym: "UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.155] +synonym: "UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] +synonym: "UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] +synonym: "uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] +synonym: "uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] +xref: EC:2.4.1.155 +xref: MetaCyc:2.4.1.155-RXN +xref: Reactome:R-HSA-975916 "Addition of GlcNAc to position 5 by MGAT5" +xref: RHEA:16921 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0030145 +name: manganese ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with manganese (Mn) ions." [GOC:ai] +synonym: "manganese binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0030146 +name: obsolete diuresis +namespace: biological_process +alt_id: GO:0003076 +def: "OBSOLETE. The process of renal water excretion." [GOC:mah, GOC:mtg_cardio, ISBN:0198506732] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "diuresis" EXACT [] +synonym: "positive regulation of renal water excretion" EXACT [] +synonym: "renal water excretion" BROAD [] +xref: Wikipedia:Diuresis +is_obsolete: true +consider: GO:0035810 + +[Term] +id: GO:0030147 +name: obsolete natriuresis +namespace: biological_process +def: "OBSOLETE. The process of renal sodium excretion." [GOC:mtg_cardio, ISBN:0198506732] +comment: This term was made obsolete because its definition was inaccurate. +synonym: "natriuresis" EXACT [] +xref: Wikipedia:Natriuresis +is_obsolete: true +consider: GO:0035815 + +[Term] +id: GO:0030148 +name: sphingolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] +synonym: "sphingolipid anabolism" EXACT [] +synonym: "sphingolipid biosynthesis" EXACT [] +synonym: "sphingolipid formation" EXACT [] +synonym: "sphingolipid synthesis" EXACT [] +xref: MetaCyc:PWY-5129 +is_a: GO:0006665 ! sphingolipid metabolic process +is_a: GO:0046467 ! membrane lipid biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0030149 +name: sphingolipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:mah, ISBN:0198506732] +synonym: "sphingolipid breakdown" EXACT [] +synonym: "sphingolipid catabolism" EXACT [] +synonym: "sphingolipid degradation" EXACT [] +is_a: GO:0006665 ! sphingolipid metabolic process +is_a: GO:0046466 ! membrane lipid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0030150 +name: protein import into mitochondrial matrix +namespace: biological_process +def: "The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together." [ISBN:0716731363] +synonym: "mitochondrial matrix protein import" EXACT [] +synonym: "mitochondrial translocation" BROAD [] +synonym: "protein transport into mitochondrial matrix" EXACT [] +is_a: GO:0044743 ! protein transmembrane import into intracellular organelle +is_a: GO:0065002 ! intracellular protein transmembrane transport +is_a: GO:0072655 ! establishment of protein localization to mitochondrion +is_a: GO:1990542 ! mitochondrial transmembrane transport +relationship: part_of GO:0006626 ! protein targeting to mitochondrion + +[Term] +id: GO:0030151 +name: molybdenum ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with molybdenum (Mo) ions." [GOC:ai] +synonym: "molybdenum binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0030152 +name: bacteriocin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary." [GOC:mah, ISBN:0198506732] +synonym: "bacteriocin anabolism" EXACT [] +synonym: "bacteriocin biosynthesis" EXACT [] +synonym: "bacteriocin formation" EXACT [] +synonym: "bacteriocin synthesis" EXACT [] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0030651 ! peptide antibiotic biosynthetic process +is_a: GO:0046224 ! bacteriocin metabolic process + +[Term] +id: GO:0030153 +name: bacteriocin immunity +namespace: biological_process +def: "A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary." [GOC:mah, ISBN:0198506732] +is_a: GO:0009404 ! toxin metabolic process + +[Term] +id: GO:0030154 +name: cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_plant +xref: Wikipedia:Cellular_differentiation +is_a: GO:0048869 ! cellular developmental process + +[Term] +id: GO:0030155 +name: regulation of cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] +synonym: "cell adhesion receptor regulator activity" RELATED [] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007155 ! cell adhesion +relationship: regulates GO:0007155 ! cell adhesion + +[Term] +id: GO:0030156 +name: benzodiazepine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the peripheral benzodiazepine receptor (PBR)." [GOC:ceb, GOC:mah, PMID:9915832] +synonym: "benzodiazepine receptor ligand" NARROW [] +synonym: "diazepam binding inhibitor activity" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0030157 +name: pancreatic juice secretion +namespace: biological_process +def: "The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GOC:mah, ISBN:0198506732] +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0022600 ! digestive system process +is_a: GO:0032941 ! secretion by tissue + +[Term] +id: GO:0030158 +name: protein xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate." [EC:2.4.2.26] +synonym: "peptide O-xylosyltransferase activity" EXACT [] +synonym: "UDP-D-xylose:core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "UDP-D-xylose:core protein xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "UDP-D-xylose:protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "UDP-xylose-core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "uridine diphosphoxylose-core protein beta-xylosyltransferase activity" EXACT [EC:2.4.2.26] +synonym: "uridine diphosphoxylose-protein xylosyltransferase activity" EXACT [EC:2.4.2.26] +xref: EC:2.4.2.26 +xref: MetaCyc:2.4.2.26-RXN +xref: Reactome:R-HSA-1878002 "XYLTs transfer Xyl to core protein" +is_a: GO:0035252 ! UDP-xylosyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0030159 +name: signaling receptor complex adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex." [GOC:mah] +synonym: "receptor signaling complex adaptor activity" EXACT [] +synonym: "receptor signaling complex scaffold activity" EXACT [] +synonym: "receptor signaling complex scaffold protein activity" EXACT [] +synonym: "receptor signalling complex scaffold activity" EXACT [] +is_a: GO:0035591 ! signaling adaptor activity + +[Term] +id: GO:0030160 +name: synaptic receptor adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule." [PMID:10506216] +synonym: "GKAP/Homer scaffold activity" NARROW [] +synonym: "GKAP/Homer scaffold protein" NARROW [] +synonym: "postsynaptic density scaffold protein" NARROW [] +is_a: GO:0030159 ! signaling receptor complex adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18409 xsd:anyURI + +[Term] +id: GO:0030161 +name: obsolete calpain inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue." [GOC:ai] +comment: This term was made obsolete because it represents a regulator of a non-existent molecular function. +synonym: "calpain inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0010859 + +[Term] +id: GO:0030162 +name: regulation of proteolysis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:mah] +synonym: "regulation of peptidolysis" EXACT [] +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006508 ! proteolysis +relationship: regulates GO:0006508 ! proteolysis + +[Term] +id: GO:0030163 +name: protein catabolic process +namespace: biological_process +alt_id: GO:0044254 +def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] +comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_drosophila +subset: goslim_pombe +synonym: "multicellular organismal protein catabolic process" NARROW [] +synonym: "pheromone catabolic process" RELATED [] +synonym: "pheromone catabolism" RELATED [] +synonym: "protein breakdown" EXACT [] +synonym: "protein catabolism" EXACT [] +synonym: "protein degradation" EXACT [] +xref: Wikipedia:Protein_catabolism +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0019538 ! protein metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0030164 +name: protein denaturation +namespace: biological_process +def: "Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds." [GOC:kd, ISBN:3110145359] +xref: Wikipedia:Denaturation#Protein_denaturation +is_a: GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0030165 +name: PDZ domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins." [GOC:go_curators, Pfam:PF00595] +synonym: "DHR-domain binding" EXACT [] +synonym: "GLGF-domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0030166 +name: proteoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GOC:mah, ISBN:0198506732] +synonym: "proteoglycan anabolism" EXACT [] +synonym: "proteoglycan biosynthesis" EXACT [] +synonym: "proteoglycan formation" EXACT [] +synonym: "proteoglycan synthesis" EXACT [] +is_a: GO:0006029 ! proteoglycan metabolic process +is_a: GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0030167 +name: proteoglycan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GOC:mah, ISBN:0198506732] +synonym: "proteoglycan breakdown" EXACT [] +synonym: "proteoglycan catabolism" EXACT [] +synonym: "proteoglycan degradation" EXACT [] +is_a: GO:0006029 ! proteoglycan metabolic process +is_a: GO:0006516 ! glycoprotein catabolic process + +[Term] +id: GO:0030168 +name: platelet activation +namespace: biological_process +def: "A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug." [http://www.graylab.ac.uk/omd/] +synonym: "blood coagulation, platelet activation" EXACT [GOC:add, GOC:pde] +is_a: GO:0001775 ! cell activation +relationship: part_of GO:0007596 ! blood coagulation + +[Term] +id: GO:0030169 +name: low-density lipoprotein particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm." [GOC:mah] +subset: goslim_chembl +synonym: "LDL binding" EXACT [] +is_a: GO:0071813 ! lipoprotein particle binding + +[Term] +id: GO:0030170 +name: pyridoxal phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6." [GOC:mah, ISBN:0198506732] +subset: goslim_metagenomics +is_a: GO:0043168 ! anion binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0070279 ! vitamin B6 binding + +[Term] +id: GO:0030171 +name: voltage-gated proton channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [PMID:28774948] +synonym: "voltage gated proton channel activity" EXACT [] +synonym: "voltage-dependent proton channel activity" EXACT [] +is_a: GO:0015252 ! proton channel activity +is_a: GO:0022843 ! voltage-gated cation channel activity + +[Term] +id: GO:0030172 +name: troponin C binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with troponin C, the calcium-binding subunit of the troponin complex." [GOC:mah, ISBN:0815316194] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0030173 +name: integral component of Golgi membrane +namespace: cellular_component +def: "The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:go_curators] +synonym: "Golgi integral membrane protein" RELATED [] +synonym: "integral to Golgi membrane" NARROW [] +is_a: GO:0031228 ! intrinsic component of Golgi membrane +is_a: GO:0031301 ! integral component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0000139 ! Golgi membrane + +[Term] +id: GO:0030174 +name: regulation of DNA-dependent DNA replication initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase." [GOC:mah] +synonym: "DNA replication licencing" EXACT [] +synonym: "DNA replication licensing" EXACT [] +synonym: "regulation of DNA replication initiation" BROAD [GOC:vw] +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006270 ! DNA replication initiation +relationship: regulates GO:0006270 ! DNA replication initiation + +[Term] +id: GO:0030175 +name: filopodium +namespace: cellular_component +alt_id: GO:0030028 +def: "Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft." [GOC:mah, GOC:pr, ISBN:0815316194] +comment: A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473. +subset: goslim_pir +xref: NIF_Subcellular:sao1046371754 +xref: Wikipedia:Filopodia +is_a: GO:0098858 ! actin-based cell projection + +[Term] +id: GO:0030176 +name: integral component of endoplasmic reticulum membrane +namespace: cellular_component +def: "The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "ER integral membrane protein" EXACT [] +synonym: "integral to endoplasmic reticulum membrane" NARROW [] +synonym: "integral to ER membrane" EXACT [] +is_a: GO:0031227 ! intrinsic component of endoplasmic reticulum membrane +is_a: GO:0031301 ! integral component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0030177 +name: positive regulation of Wnt signaling pathway +namespace: biological_process +alt_id: GO:0045811 +def: "Any process that activates or increases the frequency, rate or extent of Wnt signal transduction." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of frizzled signaling pathway" NARROW [] +synonym: "activation of Wnt receptor signaling pathway" NARROW [] +synonym: "positive regulation of frizzled signaling pathway" EXACT [] +synonym: "positive regulation of frizzled signalling pathway" EXACT [] +synonym: "positive regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "positive regulation of Wnt receptor signalling pathway" EXACT [] +synonym: "positive regulation of Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "stimulation of frizzled signaling pathway" NARROW [] +synonym: "stimulation of Wnt receptor signaling pathway" NARROW [] +synonym: "up regulation of frizzled signaling pathway" EXACT [] +synonym: "up regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "up-regulation of frizzled signaling pathway" EXACT [] +synonym: "up-regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "upregulation of frizzled signaling pathway" EXACT [] +synonym: "upregulation of Wnt receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0030111 ! regulation of Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016055 ! Wnt signaling pathway +relationship: positively_regulates GO:0016055 ! Wnt signaling pathway + +[Term] +id: GO:0030178 +name: negative regulation of Wnt signaling pathway +namespace: biological_process +alt_id: GO:0045810 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of frizzled signaling pathway" EXACT [] +synonym: "down regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "down-regulation of frizzled signaling pathway" EXACT [] +synonym: "down-regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "downregulation of frizzled signaling pathway" EXACT [] +synonym: "downregulation of Wnt receptor signaling pathway" EXACT [] +synonym: "inhibition of frizzled signaling pathway" NARROW [] +synonym: "inhibition of Wnt receptor signaling pathway" NARROW [] +synonym: "negative regulation of frizzled signaling pathway" EXACT [] +synonym: "negative regulation of frizzled signalling pathway" EXACT [] +synonym: "negative regulation of Wnt receptor signaling pathway" EXACT [] +synonym: "negative regulation of Wnt receptor signalling pathway" EXACT [] +synonym: "negative regulation of Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0030111 ! regulation of Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016055 ! Wnt signaling pathway +relationship: negatively_regulates GO:0016055 ! Wnt signaling pathway + +[Term] +id: GO:0030180 +name: obsolete solute:solute exchange +namespace: biological_process +def: "OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction." [GOC:mah] +comment: This term was made obsolete because it represents a molecular function. +synonym: "solute:solute exchange" EXACT [] +is_obsolete: true +consider: GO:0006810 +consider: GO:0015297 + +[Term] +id: GO:0030181 +name: obsolete sodium:calcium exchange +namespace: biological_process +def: "OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell." [GOC:mah, ISBN:0198506732] +comment: This term was made obsolete because it represents a function rather than a process. +synonym: "sodium:calcium exchange" EXACT [] +is_obsolete: true +consider: GO:0005432 +consider: GO:0006814 +consider: GO:0006816 + +[Term] +id: GO:0030182 +name: neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048699 ! generation of neurons + +[Term] +id: GO:0030183 +name: B cell differentiation +namespace: biological_process +alt_id: GO:0042115 +def: "The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity." [GO_REF:0000022, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "B cell development" RELATED [GOC:add] +synonym: "B lymphocyte differentiation" EXACT [] +synonym: "B-cell differentiation" EXACT [] +synonym: "B-lymphocyte differentiation" EXACT [] +is_a: GO:0030098 ! lymphocyte differentiation +is_a: GO:0042113 ! B cell activation + +[Term] +id: GO:0030184 +name: nitric oxide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other." [GOC:mah] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:0030185 ! nitric oxide transport + +[Term] +id: GO:0030185 +name: nitric oxide transport +namespace: biological_process +def: "The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015893 ! drug transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0030186 +name: melatonin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine)." [GOC:mah, ISBN:0198506732] +synonym: "melatonin metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0030187 +name: melatonin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine)." [GOC:mah, ISBN:0198506732] +synonym: "melatonin anabolism" EXACT [] +synonym: "melatonin biosynthesis" EXACT [] +synonym: "melatonin formation" EXACT [] +synonym: "melatonin synthesis" EXACT [] +is_a: GO:0030186 ! melatonin metabolic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process + +[Term] +id: GO:0030188 +name: obsolete chaperone regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulates the activity of a molecular chaperone." [GOC:mah] +comment: This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'. +synonym: "chaperone regulator activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0030189 +name: obsolete chaperone activator activity +namespace: molecular_function +def: "OBSOLETE. Increases the activity of a molecular chaperone." [GOC:mah] +comment: This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'. +synonym: "chaperone activator activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0030190 +name: obsolete chaperone inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of a molecular chaperone." [GOC:mah] +comment: This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'. +synonym: "chaperone inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0030191 +name: obsolete Hsp70/Hsc70 protein inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class." [GOC:mah] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'. +synonym: "Hsp70/Hsc70 protein inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0030192 +name: obsolete Hsp70/Hsc70 protein regulator activity +namespace: molecular_function +def: "OBSOLETE. Modulates the activity of chaperones of the Hsp70/Hsc70 class." [GOC:mah] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'. +synonym: "Hsp70/Hsc70 protein regulator activity" EXACT [] +is_obsolete: true +consider: GO:0006457 +consider: GO:0051082 +consider: GO:0051787 + +[Term] +id: GO:0030193 +name: regulation of blood coagulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood coagulation." [GOC:mah] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0050818 ! regulation of coagulation +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:1900046 ! regulation of hemostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007596 ! blood coagulation +relationship: regulates GO:0007596 ! blood coagulation + +[Term] +id: GO:0030194 +name: positive regulation of blood coagulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood coagulation." [GOC:mah] +synonym: "activation of blood coagulation" NARROW [] +synonym: "stimulation of blood coagulation" NARROW [] +synonym: "up regulation of blood coagulation" EXACT [] +synonym: "up-regulation of blood coagulation" EXACT [] +synonym: "upregulation of blood coagulation" EXACT [] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:0050820 ! positive regulation of coagulation +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:1900048 ! positive regulation of hemostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007596 ! blood coagulation +relationship: positively_regulates GO:0007596 ! blood coagulation + +[Term] +id: GO:0030195 +name: negative regulation of blood coagulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation." [GOC:mah] +synonym: "down regulation of blood coagulation" EXACT [] +synonym: "down-regulation of blood coagulation" EXACT [] +synonym: "downregulation of blood coagulation" EXACT [] +synonym: "inhibition of blood coagulation" NARROW [] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:0050819 ! negative regulation of coagulation +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:1900047 ! negative regulation of hemostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007596 ! blood coagulation +relationship: negatively_regulates GO:0007596 ! blood coagulation + +[Term] +id: GO:0030196 +name: cyanide hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide." [EC:4.2.1.66, RHEA:21720] +synonym: "formamide dehydratase activity" EXACT [EC:4.2.1.66] +synonym: "formamide hydro-lyase (cyanide-forming)" EXACT [EC:4.2.1.66] +synonym: "formamide hydro-lyase activity" EXACT [EC:4.2.1.66] +xref: EC:4.2.1.66 +xref: KEGG_REACTION:R01408 +xref: MetaCyc:CYANIDE-HYDRATASE-RXN +xref: RHEA:21720 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0030197 +name: extracellular matrix constituent, lubricant activity +namespace: molecular_function +def: "Functions as a lubricant for an extracellular matrix, such as a mucous membrane." [GOC:mah] +comment: Extracellular matrix mucin proteins may be annotated to this term. PMID:14711375, PMID:18601586 +synonym: "core extracellular matrix" BROAD [] +synonym: "core matrisome" BROAD [] +is_a: GO:0005201 ! extracellular matrix structural constituent + +[Term] +id: GO:0030198 +name: extracellular matrix organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "extracellular matrix organisation" EXACT [] +synonym: "extracellular matrix organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0043062 ! extracellular structure organization + +[Term] +id: GO:0030199 +name: collagen fibril organization +namespace: biological_process +def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194] +synonym: "collagen fibril organisation" EXACT [] +synonym: "fibrillar collagen organization" EXACT [GOC:mah] +is_a: GO:0030198 ! extracellular matrix organization +is_a: GO:0097435 ! supramolecular fiber organization +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030200 +name: heparan sulfate proteoglycan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups." [GOC:mah, ISBN:0198506732] +synonym: "heparan sulfate proteoglycan breakdown" EXACT [] +synonym: "heparan sulfate proteoglycan catabolism" EXACT [] +synonym: "heparan sulfate proteoglycan degradation" EXACT [] +synonym: "heparan sulphate proteoglycan catabolic process" EXACT [] +synonym: "heparan sulphate proteoglycan catabolism" EXACT [] +synonym: "heparin proteoglycan catabolic process" RELATED [] +is_a: GO:0030167 ! proteoglycan catabolic process +is_a: GO:0030201 ! heparan sulfate proteoglycan metabolic process + +[Term] +id: GO:0030201 +name: heparan sulfate proteoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups." [GOC:mah, ISBN:0198506732] +synonym: "heparan sulfate proteoglycan metabolism" EXACT [] +synonym: "heparan sulphate proteoglycan metabolic process" EXACT [] +synonym: "heparan sulphate proteoglycan metabolism" EXACT [] +synonym: "heparin proteoglycan metabolic process" RELATED [] +is_a: GO:0006029 ! proteoglycan metabolic process + +[Term] +id: GO:0030202 +name: heparin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:mah, ISBN:0198506732] +synonym: "heparan sulfate metabolic process" RELATED [] +synonym: "heparin metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:1903510 ! mucopolysaccharide metabolic process + +[Term] +id: GO:0030203 +name: glycosaminoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties." [ISBN:0192800981] +synonym: "glycosaminoglycan metabolism" EXACT [] +is_a: GO:0006022 ! aminoglycan metabolic process + +[Term] +id: GO:0030204 +name: chondroitin sulfate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate metabolism" EXACT [] +synonym: "chondroitin sulphate metabolic process" EXACT [] +synonym: "chondroitin sulphate metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:1903510 ! mucopolysaccharide metabolic process +relationship: part_of GO:0050654 ! chondroitin sulfate proteoglycan metabolic process + +[Term] +id: GO:0030205 +name: dermatan sulfate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate B metabolic process" EXACT [] +synonym: "chondroitin sulfate B metabolism" EXACT [] +synonym: "dermatan sulfate metabolism" EXACT [] +synonym: "dermatan sulphate metabolic process" EXACT [] +synonym: "dermatan sulphate metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1903510 ! mucopolysaccharide metabolic process +relationship: part_of GO:0050655 ! dermatan sulfate proteoglycan metabolic process + +[Term] +id: GO:0030206 +name: chondroitin sulfate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate anabolism" EXACT [] +synonym: "chondroitin sulfate biosynthesis" EXACT [] +synonym: "chondroitin sulfate formation" EXACT [] +synonym: "chondroitin sulfate synthesis" EXACT [] +synonym: "chondroitin sulphate biosynthesis" EXACT [] +synonym: "chondroitin sulphate biosynthetic process" EXACT [] +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0030204 ! chondroitin sulfate metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +relationship: part_of GO:0050650 ! chondroitin sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0030207 +name: chondroitin sulfate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate breakdown" EXACT [] +synonym: "chondroitin sulfate catabolism" EXACT [] +synonym: "chondroitin sulfate degradation" EXACT [] +synonym: "chondroitin sulphate catabolic process" EXACT [] +synonym: "chondroitin sulphate catabolism" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0030204 ! chondroitin sulfate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0030208 +name: dermatan sulfate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate B biosynthesis" EXACT [] +synonym: "chondroitin sulfate B biosynthetic process" EXACT [] +synonym: "dermatan sulfate anabolism" EXACT [] +synonym: "dermatan sulfate biosynthesis" EXACT [] +synonym: "dermatan sulfate formation" EXACT [] +synonym: "dermatan sulfate synthesis" EXACT [] +synonym: "dermatan sulphate biosynthesis" EXACT [] +synonym: "dermatan sulphate biosynthetic process" EXACT [] +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0030205 ! dermatan sulfate metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +relationship: part_of GO:0050651 ! dermatan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0030209 +name: dermatan sulfate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units." [GOC:mah, ISBN:0198506732] +synonym: "chondroitin sulfate B catabolic process" EXACT [] +synonym: "chondroitin sulfate B catabolism" EXACT [] +synonym: "dermatan sulfate breakdown" EXACT [] +synonym: "dermatan sulfate catabolism" EXACT [] +synonym: "dermatan sulfate degradation" EXACT [] +synonym: "dermatan sulphate catabolic process" EXACT [] +synonym: "dermatan sulphate catabolism" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0030205 ! dermatan sulfate metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0030210 +name: heparin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:mah, ISBN:0198506732] +synonym: "heparan sulfate biosynthetic process" RELATED [] +synonym: "heparin anabolism" EXACT [] +synonym: "heparin biosynthesis" EXACT [] +synonym: "heparin formation" EXACT [] +synonym: "heparin synthesis" EXACT [] +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0030202 ! heparin metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0030211 +name: heparin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:mah, ISBN:0198506732] +synonym: "heparan sulfate catabolic process" RELATED [] +synonym: "heparin breakdown" EXACT [] +synonym: "heparin catabolism" EXACT [] +synonym: "heparin degradation" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0030202 ! heparin metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0030212 +name: hyaluronan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] +synonym: "hyaluronan metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:1903510 ! mucopolysaccharide metabolic process + +[Term] +id: GO:0030213 +name: hyaluronan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] +synonym: "hyaluronan anabolism" EXACT [] +synonym: "hyaluronan biosynthesis" EXACT [] +synonym: "hyaluronan formation" EXACT [] +synonym: "hyaluronan synthesis" EXACT [] +is_a: GO:0006024 ! glycosaminoglycan biosynthetic process +is_a: GO:0030212 ! hyaluronan metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0030214 +name: hyaluronan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] +synonym: "hyaluronan breakdown" EXACT [] +synonym: "hyaluronan catabolism" EXACT [] +synonym: "hyaluronan degradation" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0030212 ! hyaluronan metabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0030215 +name: semaphorin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with semaphorin receptors." [GOC:ceb, PMID:12001990] +synonym: "plexin binding" NARROW [] +synonym: "plexin ligand" NARROW [] +synonym: "semaphorin receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0030216 +name: keratinocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte." [GOC:dph, GOC:mah, GOC:sdb_2009, GOC:tb] +synonym: "keratinocyte cell differentiation" EXACT [] +is_a: GO:0009913 ! epidermal cell differentiation +relationship: part_of GO:0043588 ! skin development + +[Term] +id: GO:0030217 +name: T cell differentiation +namespace: biological_process +alt_id: GO:0042112 +alt_id: GO:0046652 +def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah] +comment: Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T cell development" RELATED [GOC:add] +synonym: "T lymphocyte differentiation" EXACT [] +synonym: "T-cell differentiation" EXACT [] +synonym: "T-lymphocyte differentiation" EXACT [] +is_a: GO:0030098 ! lymphocyte differentiation +is_a: GO:0042110 ! T cell activation + +[Term] +id: GO:0030218 +name: erythrocyte differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah] +synonym: "erythrocyte cell differentiation" EXACT [] +synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph] +synonym: "RBC differentiation" EXACT [CL:0000232] +synonym: "red blood cell differentiation" EXACT [CL:0000232] +xref: Wikipedia:Erythropoiesis +is_a: GO:0030099 ! myeloid cell differentiation +relationship: part_of GO:0034101 ! erythrocyte homeostasis + +[Term] +id: GO:0030219 +name: megakaryocyte differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah] +synonym: "megakaryocyte cell differentiation" EXACT [] +is_a: GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0030220 +name: platelet formation +namespace: biological_process +def: "The process in which platelets bud from long processes extended by megakaryocytes." [GOC:mah, ISBN:0815316194] +synonym: "platelet extrusion" EXACT systematic_synonym [GOC:curators] +is_a: GO:0030099 ! myeloid cell differentiation +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0036344 ! platelet morphogenesis + +[Term] +id: GO:0030221 +name: basophil differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell." [GOC:jid, GOC:mah] +synonym: "basophil cell differentiation" EXACT [] +is_a: GO:0030851 ! granulocyte differentiation + +[Term] +id: GO:0030222 +name: eosinophil differentiation +namespace: biological_process +alt_id: GO:0035856 +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil." [GOC:add, GOC:mah] +synonym: "eosinophil cell development" RELATED [GOC:bf] +synonym: "eosinophil cell differentiation" EXACT [] +synonym: "eosinophil development" RELATED [] +is_a: GO:0030851 ! granulocyte differentiation +is_a: GO:0048468 ! cell development + +[Term] +id: GO:0030223 +name: neutrophil differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires the specialized features of a neutrophil." [GOC:mah] +synonym: "neutrophil cell differentiation" EXACT [] +synonym: "neutrophil granulocyte differentiation" EXACT [GOC:yaf] +synonym: "neutrophil granulocytopoiesis" EXACT [GOC:yaf] +is_a: GO:0030851 ! granulocyte differentiation + +[Term] +id: GO:0030224 +name: monocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte." [GOC:mah] +synonym: "monocyte cell differentiation" EXACT [] +is_a: GO:0002573 ! myeloid leukocyte differentiation +is_a: GO:1903131 ! mononuclear cell differentiation + +[Term] +id: GO:0030225 +name: macrophage differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage." [GOC:add, ISBN:0781735149] +synonym: "macrophage cell differentiation" EXACT [] +is_a: GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0030226 +name: apolipoprotein receptor activity +namespace: molecular_function +def: "Combining with an apolipoprotein to initiate a change in cell activity." [GOC:mah, ISBN:0198506732] +is_a: GO:0038024 ! cargo receptor activity +relationship: has_part GO:0034185 ! apolipoprotein binding + +[Term] +id: GO:0030227 +name: obsolete apolipoprotein E receptor activity +namespace: molecular_function +def: "OBSOLETE. Combining with apolipoprotein E to initiate a change in cell activity." [GOC:mah] +comment: This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid). +synonym: "ApoE receptor" EXACT [] +synonym: "apolipoprotein E receptor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030229 + +[Term] +id: GO:0030228 +name: lipoprotein particle receptor activity +namespace: molecular_function +def: "Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids." [GOC:bf, GOC:mah, PMID:12827279] +comment: This term is intended for cell surface receptors that bind and internalize a lipoprotein particle. For members of the lipoprotein receptor family that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children, or 'reelin receptor activity ; GO:0038025'. +synonym: "lipoprotein receptor activity" EXACT [GOC:dph] +synonym: "plasma lipoprotein particle receptor activity" NARROW [GOC:BHF] +is_a: GO:0038024 ! cargo receptor activity +relationship: has_part GO:0071813 ! lipoprotein particle binding + +[Term] +id: GO:0030229 +name: very-low-density lipoprotein particle receptor activity +namespace: molecular_function +def: "Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis." [GOC:bf, ISBN:0198506732] +synonym: "apolipoprotein E receptor activity" RELATED [GOC:rl] +synonym: "very-low-density lipoprotein receptor activity" EXACT [GOC:dph] +synonym: "VLDL receptor" EXACT [] +xref: Wikipedia:VLDL_receptor +is_a: GO:0030228 ! lipoprotein particle receptor activity +relationship: has_part GO:0034189 ! very-low-density lipoprotein particle binding + +[Term] +id: GO:0030232 +name: insulin control element activator complex +namespace: cellular_component +def: "Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription." [PMID:7935390] +synonym: "ICE activator complex" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0030233 +name: deoxynucleotide transmembrane transporter activity +namespace: molecular_function +def: "Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP." [PMID:11226231] +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +relationship: part_of GO:0030302 ! deoxynucleotide transport + +[Term] +id: GO:0030234 +name: enzyme regulator activity +namespace: molecular_function +alt_id: GO:0010576 +def: "Binds to and modulates the activity of an enzyme." [GOC:dph, GOC:mah, GOC:tb] +comment: GO:0030234 is reserved for cases when the regulator directly interacts with the enzyme. When regulation of enzyme activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'regulation of catalytic activity ; GO:0050790'. +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +subset: goslim_yeast +synonym: "catalytic regulator activity" EXACT [GOC:dph] +synonym: "enzyme modulator" EXACT [] +synonym: "metalloenzyme regulator activity" NARROW [] +is_a: GO:0098772 ! molecular function regulator +relationship: part_of GO:0050790 ! regulation of catalytic activity + +[Term] +id: GO:0030235 +name: nitric-oxide synthase regulator activity +namespace: molecular_function +def: "Modulates the activity of nitric oxide synthase." [GOC:mah] +comment: See also 'regulation of nitric-oxide synthase activity ; GO:0050999'. +synonym: "nitric oxide synthase regulator activity" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0050998 ! nitric-oxide synthase binding +relationship: regulates GO:0004517 ! nitric-oxide synthase activity + +[Term] +id: GO:0030237 +name: female sex determination +namespace: biological_process +def: "The specification of female sex of an individual organism." [GOC:mah, ISBN:0198506732] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0030238 +name: male sex determination +namespace: biological_process +def: "The specification of male sex of an individual organism." [GOC:mah] +is_a: GO:0007530 ! sex determination +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0030239 +name: myofibril assembly +namespace: biological_process +def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0031032 ! actomyosin structure organization +is_a: GO:0070925 ! organelle assembly +is_a: GO:0097435 ! supramolecular fiber organization +relationship: part_of GO:0055002 ! striated muscle cell development + +[Term] +id: GO:0030240 +name: skeletal muscle thin filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle." [GOC:ef, GOC:mah, GOC:mtg_muscle] +is_a: GO:0007015 ! actin filament organization +relationship: part_of GO:0014866 ! skeletal myofibril assembly + +[Term] +id: GO:0030241 +name: skeletal muscle myosin thick filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle." [GOC:ef, GOC:mah, GOC:mtg_muscle] +is_a: GO:0071688 ! striated muscle myosin thick filament assembly +relationship: part_of GO:0014866 ! skeletal myofibril assembly + +[Term] +id: GO:0030242 +name: autophagy of peroxisome +namespace: biological_process +def: "The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions." [GOC:autophagy, PMID:10547367, PMID:20083110] +synonym: "peroxisome degradation" BROAD [] +synonym: "pexophagy" RELATED [] +is_a: GO:0006914 ! autophagy +relationship: has_part GO:1905683 ! peroxisome disassembly + +[Term] +id: GO:0030243 +name: cellulose metabolic process +namespace: biological_process +alt_id: GO:0016177 +def: "The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation." [GOC:mah, ISBN:0198506732] +synonym: "cellulose metabolism" EXACT [] +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0030244 +name: cellulose biosynthetic process +namespace: biological_process +alt_id: GO:0016178 +def: "The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation." [GOC:mah, ISBN:0198506732] +synonym: "cellulose anabolism" EXACT [] +synonym: "cellulose biosynthesis" EXACT [] +synonym: "cellulose formation" EXACT [] +synonym: "cellulose synthesis" EXACT [] +xref: MetaCyc:PWY-1001 +is_a: GO:0030243 ! cellulose metabolic process +is_a: GO:0051274 ! beta-glucan biosynthetic process + +[Term] +id: GO:0030245 +name: cellulose catabolic process +namespace: biological_process +alt_id: GO:0016179 +def: "The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation." [GOC:mah, ISBN:0198506732] +synonym: "cellulose breakdown" EXACT [] +synonym: "cellulose catabolism" EXACT [] +synonym: "cellulose degradation" EXACT [] +is_a: GO:0030243 ! cellulose metabolic process +is_a: GO:0051275 ! beta-glucan catabolic process + +[Term] +id: GO:0030246 +name: carbohydrate binding +namespace: molecular_function +alt_id: GO:0005529 +def: "Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates." [GOC:mah] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_plant +synonym: "selectin" RELATED [] +synonym: "sugar binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0030247 +name: polysaccharide binding +namespace: molecular_function +alt_id: GO:0002506 +def: "Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:mah] +synonym: "polysaccharide assembly with MHC class II protein complex" NARROW [] +is_a: GO:0030246 ! carbohydrate binding + +[Term] +id: GO:0030248 +name: cellulose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellulose." [GOC:mah] +is_a: GO:0030247 ! polysaccharide binding + +[Term] +id: GO:0030249 +name: guanylate cyclase regulator activity +namespace: molecular_function +def: "Modulates the activity of guanylate cyclase." [GOC:mah] +is_a: GO:0010851 ! cyclase regulator activity +relationship: part_of GO:0031282 ! regulation of guanylate cyclase activity +relationship: regulates GO:0004383 ! guanylate cyclase activity + +[Term] +id: GO:0030250 +name: guanylate cyclase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of guanylate cyclase." [GOC:mah] +synonym: "guanylin" NARROW [] +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0010853 ! cyclase activator activity +is_a: GO:0030249 ! guanylate cyclase regulator activity +relationship: part_of GO:0031284 ! positive regulation of guanylate cyclase activity +relationship: positively_regulates GO:0004383 ! guanylate cyclase activity + +[Term] +id: GO:0030251 +name: guanylate cyclase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of guanylate cyclase." [GOC:mah] +is_a: GO:0010852 ! cyclase inhibitor activity +is_a: GO:0030249 ! guanylate cyclase regulator activity +relationship: negatively_regulates GO:0004383 ! guanylate cyclase activity +relationship: part_of GO:0031283 ! negative regulation of guanylate cyclase activity + +[Term] +id: GO:0030252 +name: growth hormone secretion +namespace: biological_process +def: "The regulated release of growth hormone from secretory granules into the blood." [GOC:mah] +synonym: "somatotropin secretion" EXACT [GOC:mah] +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0030253 +name: protein secretion by the type I secretion system +namespace: biological_process +def: "The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type I protein secretion system complex ; GO:0030256'. +synonym: "protein secretion by the TOSS" EXACT [] +synonym: "protein secretion by the type I protein secretion system" EXACT [] +synonym: "type I protein secretion system" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0030254 +name: protein secretion by the type III secretion system +namespace: biological_process +def: "The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type III protein secretion system complex ; GO:0030257'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted. +synonym: "protein secretion by the T3S" EXACT [] +synonym: "protein secretion by the T3SS" EXACT [] +synonym: "protein secretion by the TTSS" EXACT [] +synonym: "protein secretion by the type III protein secretion system" EXACT [] +synonym: "type III protein secretion system" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0030255 +name: protein secretion by the type IV secretion system +namespace: biological_process +def: "The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type IV protein secretion system complex ; GO:0043684'. +synonym: "protein secretion by the T4SS" EXACT [] +synonym: "protein secretion by the type IV protein secretion system" EXACT [] +synonym: "type IV protein secretion system" NARROW [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0044097 ! secretion by the type IV secretion system +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0030256 +name: type I protein secretion system complex +namespace: cellular_component +def: "A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space." [PMID:9618447] +synonym: "ABC translocator complex" BROAD [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0030257 +name: type III protein secretion system complex +namespace: cellular_component +def: "A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase." [PMID:9618447] +synonym: "T3SS complex" EXACT [] +synonym: "TTSS complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0030258 +name: lipid modification +namespace: biological_process +def: "The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid." [GOC:mah] +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0030259 +name: lipid glycosylation +namespace: biological_process +def: "Covalent attachment of a glycosyl residue to a lipid molecule." [GOC:mah] +is_a: GO:0030258 ! lipid modification +is_a: GO:0070085 ! glycosylation + +[Term] +id: GO:0030261 +name: chromosome condensation +namespace: biological_process +alt_id: GO:0000068 +def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] +synonym: "DNA condensation" BROAD [Wikipedia:DNA_condensation] +synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf] +synonym: "nuclear chromosome condensation" EXACT [GOC:bf] +is_a: GO:0006323 ! DNA packaging + +[Term] +id: GO:0030262 +name: apoptotic nuclear changes +namespace: biological_process +def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis] +synonym: "apoptotic nuclear change" NARROW [] +is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis + +[Term] +id: GO:0030263 +name: apoptotic chromosome condensation +namespace: biological_process +def: "The compaction of chromatin during apoptosis." [GOC:mah] +synonym: "pyknosis" EXACT [] +xref: Wikipedia:Pyknosis +is_a: GO:0030261 ! chromosome condensation +relationship: part_of GO:0030262 ! apoptotic nuclear changes + +[Term] +id: GO:0030264 +name: nuclear fragmentation involved in apoptotic nuclear change +namespace: biological_process +def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976] +synonym: "apoptotic nuclear fragmentation" EXACT [] +synonym: "nuclear fragmentation during apoptosis" RELATED [GOC:dph, GOC:tb] +synonym: "nucleus fragmentation" EXACT [] +is_a: GO:0071763 ! nuclear membrane organization +intersection_of: GO:0071763 ! nuclear membrane organization +intersection_of: part_of GO:0030262 ! apoptotic nuclear changes +relationship: part_of GO:0030262 ! apoptotic nuclear changes + +[Term] +id: GO:0030265 +name: phospholipase C-activating rhodopsin mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:mah, GOC:signaling, PMID:22498302, PMID:8823931] +synonym: "phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway" EXACT [GOC:bf] +synonym: "PLC-activating rhodopsin mediated signaling pathway" EXACT [GOC:bf] +synonym: "rhodopsin mediated G protein signaling, coupled to IP3 second messenger" EXACT [] +synonym: "rhodopsin mediated G protein signalling, coupled to IP3 second messenger" EXACT [] +synonym: "rhodopsin mediated G-protein signaling, coupled to IP3 second messenger" EXACT [GOC:signaling] +synonym: "rhodopsin mediated G-protein signalling, coupled to IP3 second messenger" EXACT [] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0016056 ! rhodopsin mediated signaling pathway + +[Term] +id: GO:0030266 +name: quinate 3-dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+." [EC:1.1.1.24] +synonym: "quinate:NAD 3-oxidoreductase activity" EXACT [] +synonym: "quinate:NAD 5-oxidoreductase activity" EXACT [EC:1.1.1.24] +synonym: "quinate:NAD(+) 3-oxidoreductase activity" EXACT [] +synonym: "quinate:NAD(+) 5-oxidoreductase activity" EXACT [EC:1.1.1.24] +synonym: "quinic dehydrogenase activity" BROAD [EC:1.1.1.24] +xref: EC:1.1.1.24 +xref: EC:1.1.1.282 +xref: KEGG_REACTION:R01872 +xref: MetaCyc:QUINATE-5-DEHYDROGENASE-RXN +xref: RHEA:22364 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0030267 +name: glyoxylate reductase (NADP) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+." [EC:1.1.1.79] +synonym: "glycolate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.79] +synonym: "glyoxylate reductase (NADP+)" EXACT [EC:1.1.1.79] +synonym: "NADPH-glyoxylate reductase activity" EXACT [EC:1.1.1.79] +xref: EC:1.1.1.79 +xref: MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN +xref: Reactome:R-HSA-389826 "glyoxylate + NADPH + H+ => glycolate + NADP+" +xref: RHEA:10992 +xref: Wikipedia:Glyoxylate_reductase_(NADP+) +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0030268 +name: methylenetetrahydromethanopterin dehydrogenase activity +namespace: molecular_function +alt_id: GO:0018536 +def: "Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420." [EC:1.5.98.1, RHEA:16721] +synonym: "5,10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.5.98.1] +synonym: "5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.98.1] +synonym: "N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.5.98.1] +xref: EC:1.5.98.1 +xref: KEGG_REACTION:R04456 +xref: MetaCyc:1.5.99.9-RXN +xref: RHEA:16721 +xref: UM-BBD_reactionID:r0348 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0030269 +name: tetrahydromethanopterin S-methyltransferase activity +namespace: molecular_function +alt_id: GO:0018709 +def: "Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM." [EC:2.1.1.86, RHEA:53492] +synonym: "5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity" EXACT [EC:2.1.1.86] +synonym: "N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity" EXACT [EC:2.1.1.86] +synonym: "N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity" EXACT [EC:2.1.1.86] +synonym: "tetrahydromethanopterin methyltransferase activity" EXACT [EC:2.1.1.86] +xref: EC:2.1.1.86 +xref: KEGG_REACTION:R04347 +xref: MetaCyc:2.1.1.86-RXN +xref: RHEA:53492 +xref: UM-BBD_reactionID:r0355 +is_a: GO:0008172 ! S-methyltransferase activity +is_a: GO:0042086 ! 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity + +[Term] +id: GO:0030270 +name: formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity +namespace: molecular_function +alt_id: GO:0018714 +def: "Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran." [EC:2.3.1.101, RHEA:18061] +synonym: "formylmethanofuran-tetrahydromethanopterin formyltransferase activity" EXACT [EC:2.3.1.101] +synonym: "formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity" EXACT [EC:2.3.1.101] +synonym: "formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity" EXACT [EC:2.3.1.101] +synonym: "formylmethanofuran:tetrahydromethanopterin formyltransferase activity" EXACT [EC:2.3.1.101] +synonym: "FTR" RELATED [EC:2.3.1.101] +synonym: "N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity" EXACT [EC:2.3.1.101] +xref: EC:2.3.1.101 +xref: KEGG_REACTION:R03390 +xref: MetaCyc:2.3.1.101-RXN +xref: RHEA:18061 +xref: UM-BBD_reactionID:r0346 +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0030271 +name: obsolete chymase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa." [EC:3.4.21.39] +comment: This term was made obsolete because it represents a gene product. +synonym: "chymase activity" EXACT [] +synonym: "mast cell protease I activity" NARROW [EC:3.4.21.39] +synonym: "mast cell serine proteinase" NARROW [EC:3.4.21.39] +synonym: "SK protease activity" EXACT [EC:3.4.21.39] +synonym: "skeletal muscle (SK) protease activity" NARROW [EC:3.4.21.39] +synonym: "skeletal muscle protease" NARROW [EC:3.4.21.39] +synonym: "skin chymotryptic proteinase" NARROW [EC:3.4.21.39] +xref: EC:3.4.21.39 +xref: MetaCyc:3.4.21.39-RXN +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0030272 +name: 5-formyltetrahydrofolate cyclo-ligase activity +namespace: molecular_function +alt_id: GO:0019006 +def: "Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate." [EC:6.3.3.2, RHEA:10488] +synonym: "5,10-methenyltetrahydrofolate synthetase activity" EXACT [EC:6.3.3.2] +synonym: "5-formyltetrahydrofolate cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.2] +synonym: "5-formyltetrahydrofolate cyclodehydrase" BROAD [EC:6.3.3.2] +synonym: "5-Formyltetrahydrofolate cyclodehydrase activity" EXACT [EC:6.3.3.2] +synonym: "formyltetrahydrofolic cyclodehydrase activity" EXACT [EC:6.3.3.2] +synonym: "methenyl-THF synthetase activity" EXACT [EC:6.3.3.2] +xref: EC:6.3.3.2 +xref: KEGG_REACTION:R02301 +xref: MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN +xref: Reactome:R-HSA-6801342 "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG" +xref: RHEA:10488 +is_a: GO:0016882 ! cyclo-ligase activity + +[Term] +id: GO:0030273 +name: melanin-concentrating hormone receptor activity +namespace: molecular_function +def: "Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity." [GOC:mah] +synonym: "MCH receptor" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016500 ! protein-hormone receptor activity + +[Term] +id: GO:0030274 +name: LIM domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions." [GOC:go_curators, Pfam:PF00412] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0030275 +name: LRR domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein." [GOC:go_curators, Pfam:PF00560] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0030276 +name: clathrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles." [GOC:jl, GOC:mah, ISBN:0198506732] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0030277 +name: maintenance of gastrointestinal epithelium +namespace: biological_process +def: "Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents." [GOC:mah] +is_a: GO:0010669 ! epithelial structure maintenance +is_a: GO:0022600 ! digestive system process + +[Term] +id: GO:0030278 +name: regulation of ossification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] +synonym: "regulation of bone biosynthesis" EXACT [] +synonym: "regulation of bone formation" EXACT [] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001503 ! ossification +relationship: regulates GO:0001503 ! ossification + +[Term] +id: GO:0030279 +name: negative regulation of ossification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] +synonym: "down regulation of ossification" EXACT [] +synonym: "down-regulation of ossification" EXACT [] +synonym: "downregulation of ossification" EXACT [] +synonym: "inhibition of ossification" NARROW [] +synonym: "negative regulation of bone biosynthesis" EXACT [] +synonym: "negative regulation of bone formation" EXACT [] +is_a: GO:0030278 ! regulation of ossification +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001503 ! ossification +relationship: negatively_regulates GO:0001503 ! ossification + +[Term] +id: GO:0030280 +name: structural constituent of skin epidermis +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure." [GOC:mah] +synonym: "structural constituent of epidermis" BROAD [] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0030281 +name: structural constituent of cutaneous appendage +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers." [GOC:mah, ISBN:0878932437] +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0030282 +name: bone mineralization +namespace: biological_process +def: "The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue." [GOC:mah, PMID:22936354] +synonym: "bone calcification" NARROW [] +is_a: GO:0031214 ! biomineral tissue development +relationship: part_of GO:0001503 ! ossification + +[Term] +id: GO:0030283 +name: testosterone dehydrogenase [NAD(P)] activity +namespace: molecular_function +def: "Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+." [EC:1.1.1.51] +synonym: "17beta-hydroxy steroid dehydrogenase" BROAD [EC:1.1.1.51] +synonym: "3(or 17)beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.51] +synonym: "3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase" BROAD [EC:1.1.1.51] +synonym: "3beta-hydroxy steroid dehydrogenase" BROAD [EC:1.1.1.51] +synonym: "3beta-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.51] +synonym: "beta-hydroxy steroid dehydrogenase" BROAD [EC:1.1.1.51] +xref: EC:1.1.1.51 +xref: MetaCyc:1.1.1.51-RXN +xref: Reactome:R-HSA-193064 "Reduction of androstenedione to testosterone" +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0030284 +name: estrogen receptor activity +namespace: molecular_function +def: "Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function." [GOC:signaling, PMID:17615392] +comment: For estrogen receptors that function within the nucleus to modulate transcription, consider instead annotating to the child terms 'estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038052' or 'estrogen-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038053'. +is_a: GO:0003707 ! steroid hormone receptor activity + +[Term] +id: GO:0030285 +name: integral component of synaptic vesicle membrane +namespace: cellular_component +def: "The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] +subset: goslim_synapse +synonym: "integral to synaptic vesicle membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0098563 ! intrinsic component of synaptic vesicle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0030672 ! synaptic vesicle membrane + +[Term] +id: GO:0030286 +name: dynein complex +namespace: cellular_component +def: "Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity." [ISBN:0815316194] +is_a: GO:0005875 ! microtubule associated complex +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0030287 +name: cell wall-bounded periplasmic space +namespace: cellular_component +def: "The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria." [GOC:mlg, GOC:mtg_sensu] +synonym: "cell wall bounded periplasmic space" EXACT [] +synonym: "cell wall-enclosed periplasmic space" EXACT [] +synonym: "inner wall zone" NARROW [GOC:bf, GOC:md, Wikipedia:Periplasmic_space] +synonym: "IWZ" NARROW [GOC:bf, GOC:md, Wikipedia:Periplasmic_space] +is_a: GO:0042597 ! periplasmic space + +[Term] +id: GO:0030288 +name: outer membrane-bounded periplasmic space +namespace: cellular_component +def: "The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall." [GOC:mlg, GOC:mtg_sensu] +synonym: "outer membrane bounded periplasmic space" EXACT [] +synonym: "outer membrane-enclosed periplasmic space" EXACT [] +xref: Wikipedia:Periplasmic_space +is_a: GO:0042597 ! periplasmic space +relationship: part_of GO:0030313 ! cell envelope + +[Term] +id: GO:0030289 +name: protein phosphatase 4 complex +namespace: cellular_component +def: "A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits." [GOC:bhm, PMID:10026142] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030290 +name: sphingolipid activator protein activity +namespace: molecular_function +def: "Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase." [ISBN:0198506732] +synonym: "saposin" NARROW [] +xref: Reactome:R-HSA-1605717 "Ganglioside GM2 activator presents GM2 to hexosaminidase for cleavage" +is_a: GO:0008047 ! enzyme activator activity + +[Term] +id: GO:0030291 +name: protein serine/threonine kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a protein serine/threonine kinase." [GOC:mah] +is_a: GO:0004860 ! protein kinase inhibitor activity +relationship: negatively_regulates GO:0004674 ! protein serine/threonine kinase activity +relationship: part_of GO:0071901 ! negative regulation of protein serine/threonine kinase activity + +[Term] +id: GO:0030292 +name: protein tyrosine kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a protein tyrosine kinase." [GOC:mah] +is_a: GO:0004860 ! protein kinase inhibitor activity +relationship: part_of GO:0061099 ! negative regulation of protein tyrosine kinase activity + +[Term] +id: GO:0030293 +name: transmembrane receptor protein tyrosine kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase." [GOC:mah] +is_a: GO:0030292 ! protein tyrosine kinase inhibitor activity +is_a: GO:0030547 ! receptor inhibitor activity +relationship: negatively_regulates GO:0004714 ! transmembrane receptor protein tyrosine kinase activity + +[Term] +id: GO:0030294 +name: receptor signaling protein tyrosine kinase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase." [GOC:mah] +synonym: "receptor signalling protein tyrosine kinase inhibitor activity" EXACT [] +is_a: GO:0030292 ! protein tyrosine kinase inhibitor activity + +[Term] +id: GO:0030295 +name: protein kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] +is_a: GO:0019209 ! kinase activator activity +is_a: GO:0019887 ! protein kinase regulator activity +relationship: part_of GO:0032147 ! activation of protein kinase activity + +[Term] +id: GO:0030296 +name: protein tyrosine kinase activator activity +namespace: molecular_function +def: "Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein." [GOC:ai, ISBN:0198506732] +is_a: GO:0030295 ! protein kinase activator activity +relationship: part_of GO:0061098 ! positive regulation of protein tyrosine kinase activity + +[Term] +id: GO:0030297 +name: transmembrane receptor protein tyrosine kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase." [GOC:mah] +is_a: GO:0030296 ! protein tyrosine kinase activator activity +is_a: GO:0030546 ! signaling receptor activator activity +relationship: part_of GO:0007171 ! activation of transmembrane receptor protein tyrosine kinase activity + +[Term] +id: GO:0030298 +name: receptor signaling protein tyrosine kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a receptor signaling protein tyrosine kinase." [GOC:mah] +synonym: "receptor signalling protein tyrosine kinase activator activity" EXACT [] +is_a: GO:0030296 ! protein tyrosine kinase activator activity +relationship: positively_regulates GO:0004713 ! protein tyrosine kinase activity + +[Term] +id: GO:0030299 +name: intestinal cholesterol absorption +namespace: biological_process +def: "Uptake of cholesterol into the blood by absorption from the small intestine." [GOC:mah] +is_a: GO:0030301 ! cholesterol transport +is_a: GO:0098856 ! intestinal lipid absorption +relationship: part_of GO:0044241 ! lipid digestion + +[Term] +id: GO:0030300 +name: regulation of intestinal cholesterol absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption." [GOC:mah, PMID:11099417] +is_a: GO:0032374 ! regulation of cholesterol transport +is_a: GO:1904729 ! regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030299 ! intestinal cholesterol absorption +relationship: regulates GO:0030299 ! intestinal cholesterol absorption + +[Term] +id: GO:0030301 +name: cholesterol transport +namespace: biological_process +def: "The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah, ISBN:0198506732] +is_a: GO:0015918 ! sterol transport + +[Term] +id: GO:0030302 +name: deoxynucleotide transport +namespace: biological_process +def: "The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell." [GOC:mah, ISBN:0198506732] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0030303 +name: obsolete stromelysin 2 activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak." [EC:3.4.24.17, EC:3.4.24.22] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrix metalloproteinase 10 activity" EXACT [EC:3.4.24.22] +synonym: "MMP-10" EXACT [] +synonym: "proteoglycanase 2" RELATED [EC:3.4.24.22] +synonym: "stromelysin 2 activity" EXACT [] +synonym: "transin 2 activity" EXACT [EC:3.4.24.22] +xref: EC:3.4.24.22 +xref: MetaCyc:3.4.24.22-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0030304 +name: obsolete trypsin inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase trypsin." [GOC:ai] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "trypsin inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004867 + +[Term] +id: GO:0030305 +name: heparanase activity +namespace: molecular_function +def: "Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains." [PMID:10916150] +synonym: "heparinase activity" RELATED [] +xref: Reactome:R-HSA-1667005 "Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome)" +xref: Reactome:R-HSA-1678694 "Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0030306 +name: ADP-ribosylation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells." [ISBN:0198506732] +synonym: "ARF binding" EXACT [] +is_a: GO:0031267 ! small GTPase binding + +[Term] +id: GO:0030307 +name: positive regulation of cell growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] +synonym: "activation of cell growth" NARROW [] +synonym: "stimulation of cell growth" NARROW [] +synonym: "up regulation of cell growth" EXACT [] +synonym: "up-regulation of cell growth" EXACT [] +synonym: "upregulation of cell growth" EXACT [] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0045927 ! positive regulation of growth +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016049 ! cell growth +relationship: positively_regulates GO:0016049 ! cell growth + +[Term] +id: GO:0030308 +name: negative regulation of cell growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators] +synonym: "down regulation of cell growth" EXACT [] +synonym: "down-regulation of cell growth" EXACT [] +synonym: "downregulation of cell growth" EXACT [] +synonym: "inhibition of cell growth" NARROW [] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0045926 ! negative regulation of growth +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016049 ! cell growth +relationship: negatively_regulates GO:0016049 ! cell growth + +[Term] +id: GO:0030309 +name: poly-N-acetyllactosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n." [GOC:mah, PMID:9405606] +synonym: "poly-N-acetyllactosamine metabolism" EXACT [] +is_a: GO:0006022 ! aminoglycan metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0030310 +name: poly-N-acetyllactosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n." [GOC:mah, PMID:9405606] +synonym: "poly-N-acetyllactosamine breakdown" EXACT [] +synonym: "poly-N-acetyllactosamine catabolism" EXACT [] +synonym: "poly-N-acetyllactosamine degradation" EXACT [] +is_a: GO:0006026 ! aminoglycan catabolic process +is_a: GO:0030309 ! poly-N-acetyllactosamine metabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process + +[Term] +id: GO:0030311 +name: poly-N-acetyllactosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n." [GOC:mah, PMID:9405606] +synonym: "poly-N-acetyllactosamine anabolism" EXACT [] +synonym: "poly-N-acetyllactosamine biosynthesis" EXACT [] +synonym: "poly-N-acetyllactosamine formation" EXACT [] +synonym: "poly-N-acetyllactosamine synthesis" EXACT [] +is_a: GO:0006023 ! aminoglycan biosynthetic process +is_a: GO:0030309 ! poly-N-acetyllactosamine metabolic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process + +[Term] +id: GO:0030312 +name: external encapsulating structure +namespace: cellular_component +def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators] +comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0071944 ! cell periphery + +[Term] +id: GO:0030313 +name: cell envelope +namespace: cellular_component +def: "An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present." [GOC:ds, GOC:mlg, http://pathmicro.med.sc.edu/fox/cell_envelope.htm] +subset: goslim_pir +xref: Wikipedia:Cell_envelope +is_a: GO:0031975 ! envelope +relationship: has_part GO:0005886 ! plasma membrane + +[Term] +id: GO:0030314 +name: junctional membrane complex +namespace: cellular_component +def: "Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules)." [PMID:11535622] +synonym: "triad junction" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0016528 ! sarcoplasm + +[Term] +id: GO:0030315 +name: T-tubule +namespace: cellular_component +def: "Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane." [GOC:mtg_muscle, ISBN:0815316194] +synonym: "transverse tubule" EXACT [] +synonym: "triad" RELATED [] +xref: Wikipedia:T-tubule +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0042383 ! sarcolemma + +[Term] +id: GO:0030316 +name: osteoclast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." [CL:0000092, GOC:add, ISBN:0781735149, PMID:12161749] +synonym: "osteoclast cell differentiation" EXACT [] +is_a: GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0030317 +name: flagellated sperm motility +namespace: biological_process +def: "Any process involved in the controlled movement of a flagellated sperm cell." [GOC:cilia, GOC:jl, GOC:krc] +synonym: "flagellated sperm movement" EXACT [] +synonym: "sperm motility" BROAD [] +synonym: "sperm movement" BROAD [] +xref: Wikipedia:Sperm_motility +is_a: GO:0060285 ! cilium-dependent cell motility +is_a: GO:0097722 ! sperm motility + +[Term] +id: GO:0030318 +name: melanocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a melanocyte." [GOC:mah] +synonym: "melanocyte cell differentiation" EXACT [] +synonym: "melanophore differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0030319 +name: obsolete cellular di-, tri-valent inorganic anion homeostasis +namespace: biological_process +def: "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell." [GOC:ai, GOC:mah] +comment: This term was made obsolete because it has been split. +synonym: "cellular di-, tri-valent inorganic anion homeostasis" EXACT [] +is_obsolete: true +consider: GO:0072501 +consider: GO:0072502 + +[Term] +id: GO:0030320 +name: cellular monovalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell." [GOC:ai, GOC:mah] +is_a: GO:0030002 ! cellular anion homeostasis +is_a: GO:0055083 ! monovalent inorganic anion homeostasis + +[Term] +id: GO:0030321 +name: transepithelial chloride transport +namespace: biological_process +def: "The directed movement of chloride ions from one side of an epithelium to the other." [GOC:mah] +is_a: GO:0006821 ! chloride transport +is_a: GO:0070633 ! transepithelial transport + +[Term] +id: GO:0030322 +name: stabilization of membrane potential +namespace: biological_process +def: "The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, ISBN:0198506732] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0030323 +name: respiratory tube development +namespace: biological_process +def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid] +is_a: GO:0035295 ! tube development +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0030324 +name: lung development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0030323 ! respiratory tube development +relationship: part_of GO:0060541 ! respiratory system development + +[Term] +id: GO:0030325 +name: adrenal gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells." [GOC:dgh] +synonym: "interrenal gland" RELATED [] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0030326 +name: embryonic limb morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping." [GOC:bf, GOC:jl, ISBN:0395825172] +is_a: GO:0035108 ! limb morphogenesis +is_a: GO:0035113 ! embryonic appendage morphogenesis + +[Term] +id: GO:0030327 +name: prenylated protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prenylated proteins." [GOC:mah] +synonym: "prenylated protein breakdown" EXACT [] +synonym: "prenylated protein catabolism" EXACT [] +synonym: "prenylated protein degradation" EXACT [] +is_a: GO:0019941 ! modification-dependent protein catabolic process + +[Term] +id: GO:0030328 +name: prenylcysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue." [GOC:ai] +synonym: "prenylcysteine breakdown" EXACT [] +synonym: "prenylcysteine catabolism" EXACT [] +synonym: "prenylcysteine degradation" EXACT [] +is_a: GO:0000098 ! sulfur amino acid catabolic process +is_a: GO:0030329 ! prenylcysteine metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process + +[Term] +id: GO:0030329 +name: prenylcysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue." [GOC:ai, PMID:16627894] +synonym: "prenylcysteine metabolism" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process + +[Term] +id: GO:0030330 +name: DNA damage response, signal transduction by p53 class mediator +namespace: biological_process +alt_id: GO:0006976 +def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:go_curators] +synonym: "DNA damage response, activation of p53" RELATED [] +synonym: "p53 signaling pathway" RELATED [GOC:mah, GOC:vk] +synonym: "p53-mediated DNA damage response" BROAD [] +synonym: "TP53 signaling pathway" RELATED [GOC:mah, GOC:vk] +is_a: GO:0042770 ! signal transduction in response to DNA damage +is_a: GO:0072331 ! signal transduction by p53 class mediator + +[Term] +id: GO:0030331 +name: estrogen receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an estrogen receptor." [GOC:ai] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0035258 ! steroid hormone receptor binding + +[Term] +id: GO:0030332 +name: cyclin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis." [GOC:ai] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0030334 +name: regulation of cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016477 ! cell migration +relationship: regulates GO:0016477 ! cell migration + +[Term] +id: GO:0030335 +name: positive regulation of cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] +synonym: "activation of cell migration" NARROW [] +synonym: "stimulation of cell migration" NARROW [] +synonym: "up regulation of cell migration" EXACT [] +synonym: "up-regulation of cell migration" EXACT [] +synonym: "upregulation of cell migration" EXACT [] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:2000147 ! positive regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016477 ! cell migration +relationship: positively_regulates GO:0016477 ! cell migration + +[Term] +id: GO:0030336 +name: negative regulation of cell migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] +synonym: "down regulation of cell migration" EXACT [] +synonym: "down-regulation of cell migration" EXACT [] +synonym: "downregulation of cell migration" EXACT [] +synonym: "inhibition of cell migration" NARROW [] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:2000146 ! negative regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016477 ! cell migration +relationship: negatively_regulates GO:0016477 ! cell migration + +[Term] +id: GO:0030337 +name: DNA polymerase processivity factor activity +namespace: molecular_function +def: "An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it." [GOC:mah, PMID:7903401, PMID:8087839] +synonym: "processivity clamp" EXACT [] +synonym: "sliding clamp" NARROW [GOC:jh2, PMID:23012374] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0030338 +name: CMP-N-acetylneuraminate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O." [EC:1.14.18.2] +comment: Note that this was EC:1.14.13.45. +synonym: "CMP-N-acetylneuraminate hydroxylase activity" EXACT [EC:1.14.18.2] +synonym: "CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)" EXACT [EC:1.14.18.2] +synonym: "CMP-N-acetylneuraminic acid hydroxylase activity" EXACT [] +synonym: "CMP-Neu5Ac hydroxylase activity" EXACT [EC:1.14.18.2] +synonym: "cytidine monophosphoacetylneuraminate monooxygenase activity" EXACT [EC:1.14.18.2] +synonym: "cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity" EXACT [EC:1.14.18.2] +synonym: "N-acetylneuraminic monooxygenase activity" EXACT [EC:1.14.18.2] +xref: EC:1.14.18.2 +xref: MetaCyc:1.14.13.45-RXN +is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0030339 +name: fatty-acyl-ethyl-ester synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol." [EC:3.1.1.67] +synonym: "FAEE synthase activity" EXACT [EC:3.1.1.67] +synonym: "FAEES activity" EXACT [EC:3.1.1.67] +synonym: "fatty-acyl ethyl ester synthase" EXACT [GOC:mah] +synonym: "long-chain-fatty-acyl-ethyl-ester acylhydrolase activity" EXACT [EC:3.1.1.67] +xref: EC:3.1.1.67 +xref: MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0030340 +name: hyaluronate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine." [EC:4.2.2.1] +synonym: "glucuronoglycosaminoglycan lyase activity" EXACT [EC:4.2.2.1] +synonym: "hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]" RELATED [EC:4.2.2.1] +synonym: "hyaluronidase activity" BROAD [EC:4.2.2.1] +synonym: "mucinase activity" EXACT [EC:4.2.2.1] +synonym: "spreading factor activity" RELATED [EC:4.2.2.1] +xref: EC:4.2.2.1 +xref: MetaCyc:HYALURONATE-LYASE-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0030341 +name: chondroitin AC lyase activity +namespace: molecular_function +def: "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups." [EC:4.2.2.5] +synonym: "ChnAC" RELATED [] +synonym: "chondroitin AC eliminase activity" EXACT [EC:4.2.2.5] +synonym: "chondroitin lyase activity" EXACT [] +synonym: "chondroitin sulfate lyase activity" EXACT [EC:4.2.2.5] +synonym: "chondroitinase AC" RELATED [] +synonym: "chondroitinase activity" BROAD [] +xref: EC:4.2.2.5 +xref: MetaCyc:4.2.2.5-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0030342 +name: 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol)." [PMID:8506296] +synonym: "1,25-(OH)2D3 24-hydroxylase activity" EXACT [PMID:8506296] +synonym: "calcitriol 24-hydroxylase activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-209765 "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it" +xref: Reactome:R-HSA-211950 "CYP24A1 24-hydroxylates CTL" +xref: Reactome:R-HSA-5602004 "Defective CYP24A1 does not 24-hydroxylate CALTOL" +is_a: GO:0070576 ! vitamin D 24-hydroxylase activity + +[Term] +id: GO:0030343 +name: vitamin D3 25-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O." [ISBN:0471331309, MetaCyc:RXN-9829] +synonym: "cholecalciferol 25-hydroxylase activity" EXACT [] +xref: MetaCyc:RXN-9829 +xref: Reactome:R-HSA-209845 "CYP2R1 25-hydroxylates VD3 to 25(OH)D" +xref: Reactome:R-HSA-5602147 "Defective CYP2R1 does not 25-hydroxylate vitamin D" +is_a: GO:0070643 ! vitamin D 25-hydroxylase activity +relationship: part_of GO:0036378 ! calcitriol biosynthetic process from calciol + +[Term] +id: GO:0030345 +name: structural constituent of tooth enamel +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of tooth enamel." [GOC:mah] +is_a: GO:0030021 ! extracellular matrix structural constituent conferring compression resistance + +[Term] +id: GO:0030346 +name: protein phosphatase 2B binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme protein phosphatase 2B." [GOC:jl] +synonym: "calcineurin binding" EXACT [] +synonym: "protein phosphatase 3 binding" RELATED [GOC:dph, GOC:rl] +is_a: GO:0019903 ! protein phosphatase binding + +[Term] +id: GO:0030348 +name: syntaxin-3 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the SNAP receptor syntaxin-3." [GOC:ai] +is_a: GO:0019905 ! syntaxin binding + +[Term] +id: GO:0030350 +name: iron-responsive element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins." [PMID:3198610, PMID:8710843] +synonym: "IRE binding" EXACT [] +is_a: GO:0003729 ! mRNA binding + +[Term] +id: GO:0030351 +name: inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855163 "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen" +is_a: GO:0052827 ! inositol pentakisphosphate phosphatase activity + +[Term] +id: GO:0030352 +name: inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity + +[Term] +id: GO:0030353 +name: fibroblast growth factor receptor antagonist activity +namespace: molecular_function +def: "Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist." [GOC:mah] +synonym: "FGF receptor antagonist activity" EXACT [] +synonym: "FGFR antagonist activity" EXACT [] +is_a: GO:0005104 ! fibroblast growth factor receptor binding +is_a: GO:0048019 ! receptor antagonist activity +relationship: part_of GO:0040037 ! negative regulation of fibroblast growth factor receptor signaling pathway + +[Term] +id: GO:0030354 +name: melanin-concentrating hormone activity +namespace: molecular_function +def: "The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals." [GOC:mah, PMID:11416225, PMID:9792536] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0030355 +name: obsolete small nucleolar ribonucleoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a cellular component rather than a molecular function. +synonym: "small nucleolar ribonucleoprotein" EXACT [] +synonym: "snoRNP" EXACT [] +is_obsolete: true +replaced_by: GO:0005732 + +[Term] +id: GO:0030356 +name: obsolete small cytoplasmic ribonucleoprotein +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it describes a cellular component rather than a molecular function. +synonym: "scRNP" EXACT [] +synonym: "small cytoplasmic ribonucleoprotein" EXACT [] +is_obsolete: true +replaced_by: GO:1990904 + +[Term] +id: GO:0030363 +name: obsolete pre-mRNA cleavage factor activity +namespace: molecular_function +def: "OBSOLETE. Any activity required for the process of mRNA cleavage." [GOC:mah, PMID:10357856] +comment: This term was made obsolete because it describes a biological process. +synonym: "pre-mRNA cleavage factor activity" EXACT [] +is_obsolete: true +consider: GO:0006379 + +[Term] +id: GO:0030364 +name: obsolete cleavage and polyadenylylation specificity factor activity +namespace: molecular_function +def: "OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions." [PMID:10357856] +comment: This term was made obsolete because it describes a cellular component. +synonym: "cleavage and polyadenylation specificity factor activity" EXACT [] +synonym: "cleavage and polyadenylylation specificity factor activity" EXACT [] +synonym: "cleavage/polyadenylation specificity factor activity" EXACT [] +synonym: "CPSF" EXACT [] +is_obsolete: true +replaced_by: GO:0005847 +consider: GO:0006378 +consider: GO:0006379 + +[Term] +id: GO:0030365 +name: obsolete cleavage stimulation factor activity +namespace: molecular_function +def: "OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide." [PMID:10357856] +comment: This term was made obsolete because it describes a cellular component. +synonym: "cleavage stimulation factor activity" EXACT [] +synonym: "CstF" EXACT [] +is_obsolete: true +replaced_by: GO:0005848 +consider: GO:0006379 + +[Term] +id: GO:0030366 +name: molybdopterin synthase activity +namespace: molecular_function +def: "Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis." [PMID:18154309, PMID:8514783] +xref: EC:2.8.1.12 +xref: Reactome:R-HSA-947541 "Sulfhydrylation and ring cleavage of precursor Z" +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0030367 +name: interleukin-17 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-17 receptor." [GOC:ai] +synonym: "IL-17" NARROW [] +synonym: "interleukin-17 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0030368 +name: interleukin-17 receptor activity +namespace: molecular_function +def: "Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:jl, GOC:signaling] +synonym: "IL-17 receptor activity" EXACT [GOC:mah] +synonym: "IL-17R" EXACT [] +xref: Wikipedia:Interleukin-17_receptor +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0019975 ! interleukin-17 binding + +[Term] +id: GO:0030369 +name: ICAM-3 receptor activity +namespace: molecular_function +def: "Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues." [GOC:ai, GOC:signaling, ISBN:0198506732, PMID:7515813] +comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'. +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0030370 +name: intercellular adhesion molecule-3 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1." [GOC:ceb, PMID:11473836] +synonym: "ICAM-3 receptor binding" EXACT [] +synonym: "ICAM-3 receptor ligand" NARROW [] +synonym: "intercellular adhesion molecule-3 receptor ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0030371 +name: translation repressor activity +namespace: molecular_function +def: "Antagonizes ribosome-mediated translation of mRNA into a polypeptide." [GOC:ai, GOC:clt] +is_a: GO:0045182 ! translation regulator activity +relationship: part_of GO:0017148 ! negative regulation of translation + +[Term] +id: GO:0030372 +name: high molecular weight B cell growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the high molecular weight B cell growth factor receptor." [GOC:ai] +synonym: "high molecular weight B cell growth factor receptor ligand" NARROW [] +synonym: "high molecular weight B lymphocyte growth factor receptor binding" EXACT [] +synonym: "high molecular weight B-cell growth factor receptor binding" EXACT [] +synonym: "high molecular weight B-lymphocyte growth factor receptor binding" EXACT [] +is_a: GO:0070851 ! growth factor receptor binding + +[Term] +id: GO:0030373 +name: high molecular weight B cell growth factor receptor activity +namespace: molecular_function +def: "Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity." [GOC:ai, GOC:signaling, PMID:2681271] +synonym: "high molecular weight B lymphocyte growth factor receptor activity" EXACT [] +synonym: "high molecular weight B-cell growth factor receptor activity" EXACT [] +synonym: "high molecular weight B-lymphocyte growth factor receptor activity" EXACT [] +synonym: "HMW-BCGF receptor" EXACT [PMID:2681271] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0030374 +name: nuclear receptor transcription coactivator activity +namespace: molecular_function +alt_id: GO:0038049 +def: "The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself." [GOC:dph, GOC:tb] +comment: GO:0030374 is intended for annotation of nuclear receptors that regulate transcription by binding to transcription factors or transcription factor complexes. When the nuclear receptor functions by binding directly to DNA response elements, consider instead annotating to 'nuclear receptor activity ; GO:0004879'. +synonym: "ligand-activated RNA polymerase II transcription factor binding transcription factor activity" EXACT [] +synonym: "ligand-dependent nuclear receptor transcription co-activator activity" EXACT [] +synonym: "ligand-dependent nuclear receptor transcription coactivator activity" EXACT [] +synonym: "transcription factor activity, ligand-activated RNA polymerase II transcription factor binding" EXACT [] +is_a: GO:0003713 ! transcription coactivator activity +created_by: bf +creation_date: 2011-11-29T01:53:30Z + +[Term] +id: GO:0030375 +name: thyroid hormone receptor coactivator activity +namespace: molecular_function +alt_id: GO:0010861 +def: "The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself." [GOC:dph, GOC:tb] +synonym: "thyroid hormone receptor activator activity" NARROW [] +synonym: "thyroid hormone receptor co-activator activity" EXACT [] +is_a: GO:0030374 ! nuclear receptor transcription coactivator activity + +[Term] +id: GO:0030377 +name: urokinase plasminogen activator receptor activity +namespace: molecular_function +def: "Combining with the urokinase plasminogen activator to initiate a change in cell activity." [GOC:mah, PMID:16456079] +synonym: "U-plasminogen activator receptor activity" EXACT [GOC:bf] +synonym: "uPAR" EXACT [] +synonym: "urokinase plasminogen activator receptor" EXACT [] +xref: Wikipedia:Urokinase_receptor +is_a: GO:0038023 ! signaling receptor activity +relationship: part_of GO:0038195 ! urokinase plasminogen activator signaling pathway + +[Term] +id: GO:0030378 +name: serine racemase activity +namespace: molecular_function +def: "Catalysis of the synthesis of free D-serine from L-serine." [GOC:kd] +xref: EC:5.1.1.18 +xref: MetaCyc:5.1.1.18-RXN +xref: Reactome:R-HSA-9014766 "SRR dimer:PXLP isomerises L-Ser to D-Ser" +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0030379 +name: neurotensin receptor activity, non-G protein-coupled +namespace: molecular_function +def: "Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins." [GOC:mah, GOC:signaling, PMID:9756851] +synonym: "neurotensin receptor activity, non G protein coupled" EXACT [] +synonym: "neurotensin receptor activity, non-G-protein coupled" EXACT [] +synonym: "non G protein coupled neurotensin receptor activity" EXACT [] +synonym: "non-G-protein coupled neurotensin receptor activity" EXACT [] +synonym: "non-G-protein-coupled neurotensin receptor activity" EXACT [] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0030380 +name: interleukin-17E receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-17E receptor." [GOC:ai] +synonym: "IL-17E" NARROW [] +synonym: "interleukin-17E receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0030381 +name: chorion-containing eggshell pattern formation +namespace: biological_process +def: "The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0003002 ! regionalization +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0007304 ! chorion-containing eggshell formation + +[Term] +id: GO:0030382 +name: sperm mitochondrion organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm." [GOC:dph, GOC:jl, GOC:mah, PMID:8833144] +synonym: "sperm mitochondria organisation" EXACT [] +synonym: "sperm mitochondria organization and biogenesis" RELATED [GOC:mah] +synonym: "sperm mitochondrion organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0030383 +name: obsolete host-pathogen interaction +namespace: biological_process +def: "OBSOLETE. Any interaction between a pathogen and its host organism." [GOC:jl] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "host-pathogen interaction" EXACT [] +is_obsolete: true +consider: GO:0044403 + +[Term] +id: GO:0030385 +name: ferredoxin:thioredoxin reductase activity +namespace: molecular_function +def: "Catalysis of the two-electron reduction of the disulfide of thioredoxins with electrons from ferredoxin involving a 4Fe-4S cluster and an adjacent active-site disulfide." [PMID:14769790] +is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors + +[Term] +id: GO:0030386 +name: ferredoxin:thioredoxin reductase complex +namespace: cellular_component +def: "A protein complex that possesses ferredoxin:thioredoxin reductase activity." [GOC:mah] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'ferredoxin:thioredoxin reductase activity ; GO:0030385'. +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0030387 +name: fructosamine-3-kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of fructosamine to form fructosamine-3-phosphate." [PMID:11016445] +is_a: GO:0016301 ! kinase activity + +[Term] +id: GO:0030388 +name: fructose 1,6-bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis." [ISBN:0198506732] +synonym: "fructose 1,6-bisphosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0030389 +name: fructosamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] +synonym: "fructosamine metabolism" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process + +[Term] +id: GO:0030391 +name: fructosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] +synonym: "fructosamine anabolism" EXACT [] +synonym: "fructosamine biosynthesis" EXACT [] +synonym: "fructosamine formation" EXACT [] +synonym: "fructosamine synthesis" EXACT [] +is_a: GO:0030389 ! fructosamine metabolic process +is_a: GO:0046349 ! amino sugar biosynthetic process + +[Term] +id: GO:0030392 +name: fructosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023] +synonym: "fructosamine breakdown" EXACT [] +synonym: "fructosamine catabolism" EXACT [] +synonym: "fructosamine degradation" EXACT [] +is_a: GO:0030389 ! fructosamine metabolic process +is_a: GO:0046348 ! amino sugar catabolic process + +[Term] +id: GO:0030393 +name: fructoselysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group." [GOC:ai] +synonym: "fructoselysine metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0030389 ! fructosamine metabolic process + +[Term] +id: GO:0030394 +name: fructoseglycine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group." [GOC:ai] +synonym: "fructoseglycine metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0030389 ! fructosamine metabolic process + +[Term] +id: GO:0030395 +name: lactose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk." [GOC:jl, ISBN:0192800981] +is_a: GO:0048030 ! disaccharide binding + +[Term] +id: GO:0030397 +name: membrane disassembly +namespace: biological_process +def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah] +synonym: "membrane breakdown" EXACT [] +synonym: "membrane catabolism" EXACT [] +synonym: "membrane degradation" EXACT [] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0061024 ! membrane organization + +[Term] +id: GO:0030398 +name: peroxisomal membrane disassembly +namespace: biological_process +def: "The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation." [GOC:mah, PMID:11382760] +synonym: "peroxisomal membrane breakdown" EXACT [] +synonym: "peroxisomal membrane catabolism" EXACT [] +synonym: "peroxisomal membrane degradation" EXACT [] +is_a: GO:0030397 ! membrane disassembly +is_a: GO:1903008 ! organelle disassembly +relationship: part_of GO:0030242 ! autophagy of peroxisome + +[Term] +id: GO:0030399 +name: autophagosome membrane disassembly +namespace: biological_process +def: "The controlled breakdown of the membranes of autophagosomes." [GOC:autophagy, GOC:mah] +synonym: "autophagic membrane breakdown" EXACT [] +synonym: "autophagic membrane catabolism" NARROW [GOC:autophagy] +synonym: "autophagic membrane degradation" NARROW [GOC:autophagy] +synonym: "autophagic vacuole membrane disassembly" EXACT [GOC:autophagy] +is_a: GO:0030397 ! membrane disassembly +is_a: GO:1905037 ! autophagosome organization + +[Term] +id: GO:0030400 +name: obsolete protease substrate recruitment factor activity +namespace: molecular_function +def: "OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity." [PMID:11500370] +comment: This term was made obsolete because it represents a gene product. +synonym: "protease substrate recruitment factor activity" EXACT [] +is_obsolete: true +consider: GO:0030674 + +[Term] +id: GO:0030401 +name: obsolete transcription antiterminator activity +namespace: molecular_function +def: "OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed." [ISBN:0198506732] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "transcription antiterminator activity" EXACT [] +synonym: "transcriptional antiterminator activity" EXACT [] +is_obsolete: true +consider: GO:0001072 +consider: GO:0001073 +consider: GO:0006353 + +[Term] +id: GO:0030402 +name: obsolete matrilysin-2 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrilysin-2 activity" EXACT [] +synonym: "matrix metalloproteinase 26" EXACT [] +synonym: "MMP-26" EXACT [] +xref: EC:3.4.24 +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0030403 +name: obsolete collagenase 4 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "collagenase 4 activity" EXACT [] +synonym: "matrix metalloproteinase 18" EXACT [] +synonym: "MMP-18" NARROW [] +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0030404 +name: obsolete collagenase 3 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "collagenase 3 activity" EXACT [] +synonym: "matrix metalloproteinase 13" EXACT [] +synonym: "MMP-13" EXACT [] +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0030405 +name: obsolete matrix metalloproteinase 19 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrix metalloproteinase 19 activity" EXACT [] +synonym: "MMP-19" EXACT [] +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0030406 +name: obsolete matrix metalloproteinase 25 activity +namespace: molecular_function +def: "OBSOLETE. Was not defined before being made obsolete." [GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "matrix metalloproteinase 25 activity" EXACT [] +synonym: "MMP-25" EXACT [] +synonym: "MT6-MMP" EXACT [] +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0030407 +name: formimidoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid." [EC:2.1.2.4, EC:2.1.2.5, GOC:mah] +synonym: "formiminotransferase activity" EXACT [] +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0030408 +name: glycine formimidoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine." [EC:2.1.2.4, RHEA:24288] +synonym: "5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity" EXACT [EC:2.1.2.4] +synonym: "FIG formiminotransferase activity" EXACT [EC:2.1.2.4] +synonym: "formiminoglycine formiminotransferase activity" EXACT [EC:2.1.2.4] +synonym: "glycine formiminotransferase activity" EXACT [] +xref: EC:2.1.2.4 +xref: KEGG_REACTION:R02729 +xref: MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN +xref: RHEA:24288 +is_a: GO:0030407 ! formimidoyltransferase activity + +[Term] +id: GO:0030409 +name: glutamate formimidoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate." [EC:2.1.2.5] +synonym: "5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity" EXACT [EC:2.1.2.5] +synonym: "formiminoglutamic acid transferase activity" EXACT [EC:2.1.2.5] +synonym: "formiminoglutamic formiminotransferase activity" EXACT [EC:2.1.2.5] +synonym: "glutamate formiminotransferase activity" EXACT [] +synonym: "glutamate formyltransferase activity" EXACT [EC:2.1.2.5] +xref: EC:2.1.2.5 +xref: MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN +is_a: GO:0030407 ! formimidoyltransferase activity + +[Term] +id: GO:0030410 +name: nicotianamine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine." [EC:2.5.1.43, RHEA:16481] +synonym: "S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.43] +xref: EC:2.5.1.43 +xref: KEGG_REACTION:R00075 +xref: MetaCyc:2.5.1.43-RXN +xref: RHEA:16481 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0030411 +name: scytalone dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O." [EC:4.2.1.94, RHEA:24396] +synonym: "scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)" EXACT [EC:4.2.1.94] +synonym: "scytalone 7,8-hydro-lyase activity" EXACT [EC:4.2.1.94] +xref: EC:4.2.1.94 +xref: KEGG_REACTION:R02907 +xref: MetaCyc:SCYTALONE-DEHYDRATASE-RXN +xref: RHEA:24396 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0030412 +name: formimidoyltetrahydrofolate cyclodeaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+)." [EC:4.3.1.4, RHEA:22736] +comment: Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases. +synonym: "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)" EXACT [EC:4.3.1.4] +synonym: "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)" EXACT [EC:4.3.1.4] +synonym: "formiminotetrahydrofolate cyclodeaminase activity" EXACT [EC:4.3.1.4] +xref: EC:4.3.1.4 +xref: KEGG_REACTION:R02302 +xref: MetaCyc:4.3.1.4-RXN +xref: Reactome:R-HSA-70920 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate" +xref: RHEA:22736 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0030413 +name: competence pheromone activity +namespace: molecular_function +def: "A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence." [GOC:mah, PMID:7698645] +is_a: GO:0005186 ! pheromone activity + +[Term] +id: GO:0030414 +name: peptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds." [GOC:jl] +synonym: "protease inhibitor activity" NARROW [GOC:mah] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0061134 ! peptidase regulator activity +relationship: negatively_regulates GO:0008233 ! peptidase activity +relationship: part_of GO:0010466 ! negative regulation of peptidase activity + +[Term] +id: GO:0030415 +name: obsolete carboxypeptidase A inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the enzyme carboxypeptidase A." [GOC:ai] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "carboxypeptidase A inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0030414 + +[Term] +id: GO:0030416 +name: methylamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methylamine (CH3NH2)." [ISBN:0721662544] +synonym: "methylamine metabolism" EXACT [] +synonym: "methylammonium metabolic process" EXACT [] +synonym: "methylammonium metabolism" EXACT [] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0030417 +name: nicotianamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid." [GOC:mah, PMID:10069850] +synonym: "nicotianamine metabolism" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0030418 +name: nicotianamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid." [GOC:mah, PMID:10069850] +synonym: "nicotianamine anabolism" EXACT [] +synonym: "nicotianamine biosynthesis" EXACT [] +synonym: "nicotianamine formation" EXACT [] +synonym: "nicotianamine synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0030417 ! nicotianamine metabolic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0030419 +name: nicotianamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid." [GOC:mah, PMID:10069850] +synonym: "nicotianamine breakdown" EXACT [] +synonym: "nicotianamine catabolism" EXACT [] +synonym: "nicotianamine degradation" EXACT [] +is_a: GO:0030417 ! nicotianamine metabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072352 ! tricarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0030420 +name: establishment of competence for transformation +namespace: biological_process +def: "The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation." [GOC:mah, ISBN:1555811027] +is_a: GO:0031668 ! cellular response to extracellular stimulus +relationship: part_of GO:0009294 ! DNA mediated transformation + +[Term] +id: GO:0030421 +name: defecation +namespace: biological_process +def: "The expulsion of feces from the rectum." [GOC:mah] +xref: Wikipedia:Defecation +is_a: GO:0007588 ! excretion + +[Term] +id: GO:0030422 +name: production of siRNA involved in RNA interference +namespace: biological_process +def: "Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference." [GOC:mah, PMID:11524674] +synonym: "production of guide RNAs involved in RNA interference" EXACT [GOC:mah] +synonym: "RNA interference, production of guide RNAs" EXACT [] +synonym: "RNA interference, production of siRNA" EXACT [GOC:mah] +is_a: GO:0070918 ! production of small RNA involved in gene silencing by RNA +relationship: part_of GO:0016246 ! RNA interference + +[Term] +id: GO:0030423 +name: targeting of mRNA for destruction involved in RNA interference +namespace: biological_process +def: "The process in which small interfering RNAs target cognate mRNA molecules for degradation." [PMID:11524674] +synonym: "RNA interference, targeting of mRNA for destruction" EXACT [GOC:mah] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0016246 ! RNA interference + +[Term] +id: GO:0030424 +name: axon +namespace: cellular_component +def: "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." [GOC:nln, ISBN:0198506732] +xref: NIF_Subcellular:sao1770195789 +xref: Wikipedia:Axon +is_a: GO:0043005 ! neuron projection + +[Term] +id: GO:0030425 +name: dendrite +namespace: cellular_component +def: "A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." [GOC:aruk, GOC:bc, GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732] +xref: NIF_Subcellular:sao1211023249 +xref: Wikipedia:Dendrite +is_a: GO:0043005 ! neuron projection +relationship: part_of GO:0097447 ! dendritic tree + +[Term] +id: GO:0030426 +name: growth cone +namespace: cellular_component +def: "The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic." [GOC:aruk, GOC:bc, ISBN:0815316194, PMID:10082468] +xref: Wikipedia:Growth_cone +is_a: GO:0030427 ! site of polarized growth +relationship: part_of GO:0150034 ! distal axon + +[Term] +id: GO:0030427 +name: site of polarized growth +namespace: cellular_component +alt_id: GO:0000134 +alt_id: GO:0030483 +def: "Any part of a cell where non-isotropic growth takes place." [GOC:mah] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0030428 +name: cell septum +namespace: cellular_component +def: "A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." [GOC:clt, ISBN:0471940526] +subset: goslim_pir +synonym: "cross wall" EXACT [] +synonym: "septum" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0030429 +name: kynureninase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine." [EC:3.7.1.3] +synonym: "kynurenine hydrolase activity" EXACT [EC:3.7.1.3] +synonym: "L-kynurenine hydrolase activity" EXACT [EC:3.7.1.3] +xref: EC:3.7.1.3 +xref: MetaCyc:KYNURENINASE-RXN +xref: Reactome:R-HSA-71217 "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine" +xref: RHEA:16813 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0030430 +name: host cell cytoplasm +namespace: cellular_component +alt_id: GO:0097679 +def: "The cytoplasm of a host cell." [GOC:mah] +synonym: "other organism cytoplasm" RELATED [] +is_a: GO:0033646 ! host intracellular part +created_by: pr +creation_date: 2014-12-01T14:14:21Z + +[Term] +id: GO:0030431 +name: sleep +namespace: biological_process +def: "Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain." [ISBN:0192800981] +subset: goslim_pir +synonym: "diapause" RELATED [] +synonym: "dormancy" RELATED [] +synonym: "lethargus" RELATED [] +xref: Wikipedia:Sleep +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0030432 +name: peristalsis +namespace: biological_process +def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732] +xref: Wikipedia:Peristalsis +is_a: GO:0014821 ! phasic smooth muscle contraction + +[Term] +id: GO:0030433 +name: ubiquitin-dependent ERAD pathway +namespace: biological_process +def: "The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome." [GOC:mah, GOC:rb, PMID:14607247, PMID:19520858] +comment: See also the biological process terms 'ERAD pathway ; GO:0036503', 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'. +synonym: "endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "endoplasmic reticulum-associated ubiqutin-dependent protein catabolism" EXACT [] +synonym: "ER-associated ubiquitin-dependent protein breakdown" EXACT [] +synonym: "ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:vw] +synonym: "ER-associated ubiquitin-dependent protein catabolism" EXACT [] +synonym: "ER-associated ubiquitin-dependent protein degradation" EXACT [] +synonym: "ERAD" BROAD [] +synonym: "ubiquitin-dependent proteasomal protein catabolism of ER proteins" EXACT [GOC:bf] +is_a: GO:0036503 ! ERAD pathway +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0030435 +name: sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction." [GOC:mah, GOC:pamgo_curators, ISBN:0072992913] +comment: Note that the synonym 'spore differentiation', like the term name and definition, refers to differentiation into a spore rather than any subsequent developmental changes that a spore may undergo. +synonym: "cellular spore formation by sporulation" EXACT [GOC:dph, GOC:tb] +synonym: "spore biosynthesis" EXACT [] +synonym: "spore differentiation" EXACT [] +synonym: "spore formation" EXACT [] +xref: Wikipedia:Sporogenesis +is_a: GO:0030154 ! cell differentiation +is_a: GO:0043934 ! sporulation +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0030436 +name: asexual sporulation +namespace: biological_process +def: "The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi." [GOC:mah, PMID:9529886] +subset: goslim_aspergillus +synonym: "asexual reproductive sporulation" EXACT [] +synonym: "asexual spore formation" EXACT [] +synonym: "mitotic spore formation" EXACT [] +synonym: "mitotic sporulation" EXACT [] +is_a: GO:0019954 ! asexual reproduction +is_a: GO:0043934 ! sporulation +property_value: RO:0002161 NCBITaxon:33083 + +[Term] +id: GO:0030437 +name: ascospore formation +namespace: biological_process +alt_id: GO:0007151 +def: "The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)." [GOC:di, GOC:mah, GOC:mcc, PMID:16339736] +comment: Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked. +subset: goslim_pombe +synonym: "ascospore biosynthesis" EXACT [] +synonym: "spore formation" BROAD [] +synonym: "sporulation" BROAD [] +is_a: GO:0022413 ! reproductive process in single-celled organism +is_a: GO:0043935 ! sexual sporulation resulting in formation of a cellular spore +is_a: GO:0048468 ! cell development + +[Term] +id: GO:0030438 +name: obsolete MAPKKK cascade during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "MAPKKK cascade during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030439 +name: obsolete activation of MAPK during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPK during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030440 +name: obsolete activation of MAPKK during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKK during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030441 +name: obsolete activation of MAPKKK during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKKK during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030442 +name: obsolete inactivation of MAPK during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "inactivation of MAPK during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030443 +name: obsolete nuclear translocation of MAPK during sporulation (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mcc] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "nuclear translocation of MAPK during sporulation (sensu Fungi)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030444 +name: obsolete microtubule depolymerization during nuclear congression +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because the entire branch of the ontology was changed. +synonym: "microtubule depolymerization during nuclear congression" EXACT [] +is_obsolete: true +replaced_by: GO:0007019 + +[Term] +id: GO:0030445 +name: yeast-form cell wall +namespace: cellular_component +def: "The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form." [GOC:mah, GOC:mcc] +comment: See also the Fungal Anatomy Ontology term 'vegetative cell ; FAO:0000032'. +is_a: GO:0009277 ! fungal-type cell wall + +[Term] +id: GO:0030446 +name: hyphal cell wall +namespace: cellular_component +def: "The cell wall surrounding a fungal hypha." [GOC:mah] +comment: See also the Fungal Anatomy Ontology term 'hypha ; FAO:0001001'. +is_a: GO:0009277 ! fungal-type cell wall + +[Term] +id: GO:0030447 +name: filamentous growth +namespace: biological_process +def: "The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:mcc, PMID:11729141] +subset: goslim_aspergillus +subset: goslim_candida +is_a: GO:0040007 ! growth + +[Term] +id: GO:0030448 +name: hyphal growth +namespace: biological_process +alt_id: GO:0075061 +def: "Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls." [GOC:mcc, ISBN:0471522295] +subset: goslim_candida +synonym: "formation of symbiont invasive hypha in host" EXACT [] +synonym: "formation of symbiont invasive hypha within host" EXACT [] +synonym: "formation of symbiont invasive hypha within host during symbiotic interaction" EXACT [] +synonym: "invasive hyphal growth" EXACT [] +synonym: "symbiont invasive hypha formation within host" EXACT [] +is_a: GO:0030447 ! filamentous growth +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI + +[Term] +id: GO:0030449 +name: regulation of complement activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of complement activation." [GOC:go_curators] +synonym: "regulation of complement cascade" EXACT [GOC:add] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0002920 ! regulation of humoral immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006956 ! complement activation +relationship: regulates GO:0006956 ! complement activation + +[Term] +id: GO:0030450 +name: regulation of complement activation, classical pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the classical pathway of complement activation." [GOC:go_curators] +synonym: "regulation of complement cascade, classical pathway" EXACT [GOC:add] +is_a: GO:0002923 ! regulation of humoral immune response mediated by circulating immunoglobulin +is_a: GO:0030449 ! regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006958 ! complement activation, classical pathway +relationship: regulates GO:0006958 ! complement activation, classical pathway + +[Term] +id: GO:0030451 +name: regulation of complement activation, alternative pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation." [GOC:go_curators] +synonym: "regulation of complement cascade, alternative pathway" EXACT [GOC:add] +is_a: GO:0030449 ! regulation of complement activation +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006957 ! complement activation, alternative pathway +relationship: regulates GO:0006957 ! complement activation, alternative pathway + +[Term] +id: GO:0030455 +name: obsolete MAPKKK cascade (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. MAPKKK cascade involved in transducing mating pheromone signal in a fungus." [GOC:mah] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "MAPKKK cascade (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030456 +name: obsolete activation of MAPK (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPK (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030457 +name: obsolete activation of MAPKK (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKK (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030458 +name: obsolete activation of MAPKKK (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "activation of MAPKKK (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030459 +name: obsolete inactivation of MAPK (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "inactivation of MAPK (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030460 +name: obsolete nuclear translocation of MAPK (mating sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:elh] +comment: This term was made obsolete because it is a gene product specific term. +synonym: "nuclear translocation of MAPK (mating sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0000750 + +[Term] +id: GO:0030463 +name: obsolete cell aging (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'. +synonym: "cell aging (sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0007569 + +[Term] +id: GO:0030464 +name: obsolete aging dependent sterility (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:sgd_curators] +comment: This term was made obsolete because it reflected a trait or phenotype. +synonym: "aging dependent sterility (sensu Fungi)" EXACT [] +is_obsolete: true +consider: GO:0030466 + +[Term] +id: GO:0030465 +name: obsolete autophagic death (sensu Fungi) +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because a more correct term has been created. +synonym: "autophagic death (sensu Fungi)" EXACT [] +is_obsolete: true +consider: GO:0048102 + +[Term] +id: GO:0030466 +name: silent mating-type cassette heterochromatin assembly +namespace: biological_process +alt_id: GO:0006347 +alt_id: GO:0035389 +def: "Repression of transcription at silent mating-type loci by alteration of the structure of chromatin." [GOC:mcc] +synonym: "aging-dependent sterility" NARROW [] +synonym: "chromatin silencing at HML and HMR" NARROW [] +synonym: "chromatin silencing at silent mating-type cassette" EXACT [] +synonym: "establishment of chromatin silencing at silent mating-type cassette" RELATED [] +synonym: "heterochromatic silencing at silent mating-type cassette" EXACT [] +synonym: "silent mating-type cassette chromatin silencing" EXACT [GOC:mah] +is_a: GO:0031507 ! heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI + +[Term] +id: GO:0030470 +name: obsolete spore germination (sensu Fungi) +namespace: biological_process +alt_id: GO:0007153 +def: "OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751)." [GOC:mcc] +comment: This term was made obsolete because a sensu term was not needed. +synonym: "germination (sensu Saccharomyces)" NARROW [] +synonym: "spore germination (sensu Fungi)" EXACT [] +is_obsolete: true +replaced_by: GO:0009847 + +[Term] +id: GO:0030471 +name: obsolete spindle pole body and microtubule cycle (sensu Fungi) +namespace: biological_process +alt_id: GO:0007102 +def: "OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751)." [ISBN:0879693649] +comment: This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity. +synonym: "spindle pole body and microtubule cycle (sensu Fungi)" EXACT [] +synonym: "spindle pole body and microtubule cycle (sensu Saccharomyces)" NARROW [] +is_obsolete: true +consider: GO:0007051 +consider: GO:0051300 + +[Term] +id: GO:0030473 +name: nuclear migration along microtubule +namespace: biological_process +alt_id: GO:0000065 +def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators] +synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT [] +synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT [] +synonym: "microtubule-dependent nuclear positioning" EXACT [] +synonym: "microtubule-dependent nucleus positioning" EXACT [] +synonym: "microtubule-mediated nuclear migration" EXACT [] +synonym: "nuclear migration, microtubule-mediated" EXACT [] +synonym: "nuclear movement, microtubule-mediated" BROAD [] +synonym: "nucleus migration" BROAD [] +synonym: "transport of nucleus by microtubules" EXACT [] +synonym: "transport of nucleus, microtubule-mediated" EXACT [] +is_a: GO:0007097 ! nuclear migration +is_a: GO:0072384 ! organelle transport along microtubule + +[Term] +id: GO:0030474 +name: spindle pole body duplication +namespace: biological_process +alt_id: GO:0007103 +alt_id: GO:0031046 +def: "Construction of a new spindle pole body." [GOC:clt] +synonym: "spindle pole body assembly" EXACT [] +synonym: "spindle pole body biogenesis" EXACT [] +synonym: "spindle pole body biosynthesis" EXACT [] +synonym: "spindle pole body duplication associated with nuclear envelope" EXACT [] +synonym: "spindle pole body duplication in cytoplasm" EXACT [] +synonym: "spindle pole body formation" EXACT [] +synonym: "spindle pole body replication" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0051300 ! spindle pole body organization + +[Term] +id: GO:0030476 +name: ascospore wall assembly +namespace: biological_process +alt_id: GO:0007152 +def: "The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae." [GOC:mcc, PMID:14702385] +synonym: "spore wall assembly" BROAD [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0042244 ! spore wall assembly +is_a: GO:0071940 ! fungal-type cell wall assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0070591 ! ascospore wall biogenesis + +[Term] +id: GO:0030478 +name: actin cap +namespace: cellular_component +alt_id: GO:0000143 +def: "Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae." [GOC:mah, PMID:21494665] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030864 ! cortical actin cytoskeleton + +[Term] +id: GO:0030479 +name: actin cortical patch +namespace: cellular_component +alt_id: GO:0005857 +def: "An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae." [GOC:mah, GOC:vw, ISBN:0879693568, ISBN:0879693649, PMID:16959963] +synonym: "actin patch" EXACT [] +is_a: GO:0061645 ! endocytic patch +relationship: part_of GO:0030864 ! cortical actin cytoskeleton + +[Term] +id: GO:0030484 +name: obsolete muscle fiber +namespace: cellular_component +def: "OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:mah, ISBN:0815316194] +comment: This term was made obsolete because a muscle fiber is a cell type rather than a cell component. To update annotations, consider the external ontology term 'muscle cell ; CL:0000187'. +synonym: "muscle fiber" EXACT [] +synonym: "muscle fibre" EXACT [] +is_obsolete: true +consider: GO:0043292 + +[Term] +id: GO:0030485 +name: smooth muscle contractile fiber +namespace: cellular_component +def: "The contractile fiber of smooth muscle cells." [GOC:mah] +synonym: "smooth muscle fiber" BROAD [] +synonym: "smooth muscle fibre" EXACT [] +is_a: GO:0043292 ! contractile fiber + +[Term] +id: GO:0030486 +name: smooth muscle dense body +namespace: cellular_component +def: "Electron-dense region associated with a smooth muscle contractile fiber." [GOC:mah, ISBN:0815316194] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030485 ! smooth muscle contractile fiber + +[Term] +id: GO:0030487 +name: inositol-4,5-bisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate." [GOC:mah] +is_a: GO:0016312 ! inositol bisphosphate phosphatase activity + +[Term] +id: GO:0030488 +name: tRNA methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule." [GOC:mah] +is_a: GO:0001510 ! RNA methylation +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0030489 +name: obsolete processing of 27S pre-rRNA +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:curators] +comment: This term was made obsolete because it was not defined and did not correspond to the production of a single specific mature rRNA product. +synonym: "processing of 27S pre-rRNA" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030490 +name: maturation of SSU-rRNA +namespace: biological_process +def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule." [GOC:curators] +synonym: "processing of 20S pre-rRNA" NARROW [] +synonym: "SSU-rRNA maturation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006364 ! rRNA processing +relationship: part_of GO:0042274 ! ribosomal small subunit biogenesis + +[Term] +id: GO:0030491 +name: heteroduplex formation +namespace: biological_process +def: "The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:10357855] +is_a: GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0030492 +name: hemoglobin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:jl] +synonym: "globin binding" BROAD [] +synonym: "haemoglobin binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030493 +name: bacteriochlorophyll metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants." [GOC:mah, ISBN:0198506732] +synonym: "bacteriochlorophyll metabolism" EXACT [] +is_a: GO:0015994 ! chlorophyll metabolic process + +[Term] +id: GO:0030494 +name: bacteriochlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants." [GOC:mah, ISBN:0198506732] +synonym: "bacteriochlorophyll anabolism" EXACT [] +synonym: "bacteriochlorophyll biosynthesis" EXACT [] +synonym: "bacteriochlorophyll formation" EXACT [] +synonym: "bacteriochlorophyll synthesis" EXACT [] +is_a: GO:0015995 ! chlorophyll biosynthetic process +is_a: GO:0030493 ! bacteriochlorophyll metabolic process + +[Term] +id: GO:0030495 +name: bacteriochlorophyll catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants." [GOC:go_curators] +synonym: "bacteriochlorophyll breakdown" EXACT [] +synonym: "bacteriochlorophyll catabolism" EXACT [] +synonym: "bacteriochlorophyll degradation" EXACT [] +is_a: GO:0015996 ! chlorophyll catabolic process +is_a: GO:0030493 ! bacteriochlorophyll metabolic process + +[Term] +id: GO:0030496 +name: midbody +namespace: cellular_component +def: "A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis." [ISBN:0815316194] +subset: goslim_pir +xref: Wikipedia:Midbody_(cell_biology) +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0030497 +name: fatty acid elongation +namespace: biological_process +def: "The elongation of a fatty acid chain by the sequential addition of two-carbon units." [ISBN:0716720094] +is_a: GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0030500 +name: regulation of bone mineralization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone mineralization." [GOC:go_curators] +is_a: GO:0030278 ! regulation of ossification +is_a: GO:0070167 ! regulation of biomineral tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030282 ! bone mineralization +relationship: regulates GO:0030282 ! bone mineralization + +[Term] +id: GO:0030501 +name: positive regulation of bone mineralization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone mineralization." [GOC:go_curators] +synonym: "activation of bone mineralization" NARROW [] +synonym: "stimulation of bone mineralization" NARROW [] +synonym: "up regulation of bone mineralization" EXACT [] +synonym: "up-regulation of bone mineralization" EXACT [] +synonym: "upregulation of bone mineralization" EXACT [] +is_a: GO:0030500 ! regulation of bone mineralization +is_a: GO:0045778 ! positive regulation of ossification +is_a: GO:0070169 ! positive regulation of biomineral tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030282 ! bone mineralization +relationship: positively_regulates GO:0030282 ! bone mineralization + +[Term] +id: GO:0030502 +name: negative regulation of bone mineralization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization." [GOC:go_curators] +synonym: "down regulation of bone mineralization" EXACT [] +synonym: "down-regulation of bone mineralization" EXACT [] +synonym: "downregulation of bone mineralization" EXACT [] +synonym: "inhibition of bone mineralization" NARROW [] +is_a: GO:0030279 ! negative regulation of ossification +is_a: GO:0030500 ! regulation of bone mineralization +is_a: GO:0070168 ! negative regulation of biomineral tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030282 ! bone mineralization +relationship: negatively_regulates GO:0030282 ! bone mineralization + +[Term] +id: GO:0030504 +name: inorganic diphosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of inorganic diphosphate across a membrane." [PMID:11326272] +synonym: "inorganic pyrophosphate transporter activity" EXACT [] +xref: Reactome:R-HSA-5226964 "ANKH transports PPi from cytosol to extracellular region" +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:0030505 ! inorganic diphosphate transport + +[Term] +id: GO:0030505 +name: inorganic diphosphate transport +namespace: biological_process +def: "The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "inorganic pyrophosphate transport" EXACT [] +is_a: GO:0015698 ! inorganic anion transport + +[Term] +id: GO:0030506 +name: ankyrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins." [GOC:mah, ISBN:0198506732] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0030507 +name: spectrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers." [GOC:mah, ISBN:0198506732] +is_a: GO:0008092 ! cytoskeletal protein binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0030508 +name: obsolete thiol-disulfide exchange intermediate activity +namespace: molecular_function +def: "OBSOLETE. Functions as an exchange intermediate in thiol-disulfide exchange reactions." [GOC:kd, GOC:mah] +comment: This term was made obsolete because it represents a combination of gene product features and involvement in a biological process. +synonym: "glutaredoxin" NARROW [] +synonym: "thiol-disulfide exchange intermediate activity" EXACT [] +synonym: "thiol-disulphide exchange intermediate activity" EXACT [] +synonym: "thioredoxin" NARROW [] +is_obsolete: true +consider: GO:0003756 +consider: GO:0015036 + +[Term] +id: GO:0030509 +name: BMP signaling pathway +namespace: biological_process +alt_id: GO:0008101 +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:0878932437, PMID:17428827, PR:000000034] +synonym: "BMP receptor signaling pathway" RELATED [] +synonym: "BMP signalling pathway" EXACT [] +synonym: "bone morphogenetic protein signaling pathway" EXACT [] +synonym: "bone morphogenetic protein signalling pathway" EXACT [] +synonym: "decapentaplegic receptor signaling pathway" NARROW [GOC:bf, GOC:sart, GOC:signaling] +synonym: "decapentaplegic receptor signalling pathway" NARROW [] +synonym: "decapentaplegic signaling pathway" NARROW [] +synonym: "dpp receptor signaling pathway" NARROW [] +synonym: "dpp receptor signalling pathway" NARROW [] +synonym: "dpp signaling pathway" NARROW [GOC:bf] +is_a: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +relationship: part_of GO:0071773 ! cellular response to BMP stimulus + +[Term] +id: GO:0030510 +name: regulation of BMP signaling pathway +namespace: biological_process +alt_id: GO:0090097 +def: "Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway." [GOC:mah] +synonym: "regulation of BMP receptor signaling pathway" RELATED [] +synonym: "regulation of BMP signalling pathway" EXACT [] +synonym: "regulation of bone morphogenetic protein signaling pathway" EXACT [] +synonym: "regulation of bone morphogenetic protein signalling pathway" EXACT [] +synonym: "regulation of decapentaplegic receptor signaling pathway" NARROW [GOC:bf] +synonym: "regulation of decapentaplegic receptor signalling pathway" NARROW [GOC:mah] +synonym: "regulation of decapentaplegic signaling pathway" NARROW [] +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030509 ! BMP signaling pathway +relationship: regulates GO:0030509 ! BMP signaling pathway +created_by: tb +creation_date: 2009-11-13T10:49:14Z + +[Term] +id: GO:0030511 +name: positive regulation of transforming growth factor beta receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity." [GOC:go_curators] +synonym: "activation of transforming growth factor beta receptor signaling pathway" NARROW [] +synonym: "positive regulation of TGF-beta receptor signaling pathway" EXACT [] +synonym: "positive regulation of TGFbeta receptor signaling pathway" EXACT [] +synonym: "positive regulation of transforming growth factor beta receptor signalling pathway" EXACT [] +synonym: "stimulation of transforming growth factor beta receptor signaling pathway" NARROW [] +synonym: "up regulation of transforming growth factor beta receptor signaling pathway" EXACT [] +synonym: "up-regulation of transforming growth factor beta receptor signaling pathway" EXACT [] +synonym: "upregulation of transforming growth factor beta receptor signaling pathway" EXACT [] +is_a: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway +is_a: GO:0090100 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:1903846 ! positive regulation of cellular response to transforming growth factor beta stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway +relationship: positively_regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway + +[Term] +id: GO:0030512 +name: negative regulation of transforming growth factor beta receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway." [GOC:mah] +synonym: "down regulation of transforming growth factor beta receptor signaling pathway" EXACT [] +synonym: "down-regulation of transforming growth factor beta receptor signaling pathway" EXACT [] +synonym: "downregulation of transforming growth factor beta receptor signaling pathway" EXACT [] +synonym: "inhibition of transforming growth factor beta receptor signaling pathway" NARROW [] +synonym: "negative regulation of TGF-beta receptor signaling pathway" EXACT [] +synonym: "negative regulation of TGFbeta receptor signaling pathway" EXACT [] +synonym: "negative regulation of transforming growth factor beta receptor signalling pathway" EXACT [] +is_a: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:1903845 ! negative regulation of cellular response to transforming growth factor beta stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway +relationship: negatively_regulates GO:0007179 ! transforming growth factor beta receptor signaling pathway + +[Term] +id: GO:0030513 +name: positive regulation of BMP signaling pathway +namespace: biological_process +alt_id: GO:0090098 +def: "Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity." [GOC:go_curators] +synonym: "activation of BMP signaling pathway" NARROW [] +synonym: "positive regulation of BMP receptor signaling pathway" RELATED [] +synonym: "positive regulation of BMP signalling pathway" EXACT [] +synonym: "positive regulation of bone morphogenetic protein signaling pathway" EXACT [] +synonym: "positive regulation of bone morphogenetic protein signalling pathway" EXACT [] +synonym: "positive regulation of decapentaplegic receptor signaling pathway" NARROW [GOC:bf] +synonym: "positive regulation of decapentaplegic receptor signalling pathway" NARROW [GOC:mah] +synonym: "positive regulation of decapentaplegic signaling pathway" NARROW [] +synonym: "stimulation of BMP signaling pathway" NARROW [] +synonym: "up regulation of BMP signaling pathway" EXACT [] +synonym: "up-regulation of BMP signaling pathway" EXACT [] +synonym: "upregulation of BMP signaling pathway" EXACT [] +is_a: GO:0030510 ! regulation of BMP signaling pathway +is_a: GO:0090100 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030509 ! BMP signaling pathway +relationship: positively_regulates GO:0030509 ! BMP signaling pathway +created_by: tb +creation_date: 2009-11-13T10:50:41Z + +[Term] +id: GO:0030514 +name: negative regulation of BMP signaling pathway +namespace: biological_process +alt_id: GO:0090099 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway." [GOC:go_curators] +synonym: "down regulation of BMP signaling pathway" EXACT [] +synonym: "down-regulation of BMP signaling pathway" EXACT [] +synonym: "downregulation of BMP signaling pathway" EXACT [] +synonym: "inhibition of BMP signaling pathway" NARROW [] +synonym: "negative regulation of BMP receptor signaling pathway" RELATED [] +synonym: "negative regulation of BMP signalling pathway" EXACT [] +synonym: "negative regulation of bone morphogenetic protein signaling pathway" EXACT [] +synonym: "negative regulation of bone morphogenetic protein signalling pathway" EXACT [] +synonym: "negative regulation of decapentaplegic receptor signaling pathway" NARROW [GOC:bf] +synonym: "negative regulation of decapentaplegic receptor signalling pathway" NARROW [GOC:mah] +synonym: "negative regulation of decapentaplegic signaling pathway" NARROW [] +is_a: GO:0030510 ! regulation of BMP signaling pathway +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030509 ! BMP signaling pathway +relationship: negatively_regulates GO:0030509 ! BMP signaling pathway +created_by: tb +creation_date: 2009-11-13T10:51:30Z + +[Term] +id: GO:0030515 +name: snoRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with small nucleolar RNA." [GOC:mah] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0030516 +name: regulation of axon extension +namespace: biological_process +def: "Any process that modulates the rate, direction or extent of axon extension." [GOC:go_curators] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0050770 ! regulation of axonogenesis +is_a: GO:0061387 ! regulation of extent of cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048675 ! axon extension +relationship: regulates GO:0048675 ! axon extension + +[Term] +id: GO:0030517 +name: negative regulation of axon extension +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth." [GOC:mah] +synonym: "down regulation of axon extension" EXACT [] +synonym: "down-regulation of axon extension" EXACT [] +synonym: "downregulation of axon extension" EXACT [] +synonym: "inhibition of axon extension" NARROW [] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0030516 ! regulation of axon extension +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0050771 ! negative regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048675 ! axon extension +relationship: negatively_regulates GO:0048675 ! axon extension + +[Term] +id: GO:0030518 +name: intracellular steroid hormone receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands." [GOC:mah, GOC:signaling] +synonym: "steroid hormone receptor signaling pathway" BROAD [GOC:bf] +synonym: "steroid hormone receptor signalling pathway" BROAD [GOC:bf] +is_a: GO:0030522 ! intracellular receptor signaling pathway +is_a: GO:0043401 ! steroid hormone mediated signaling pathway + +[Term] +id: GO:0030519 +name: snoRNP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a small nucleolar ribonucleoprotein particle." [GOC:mah] +is_a: GO:0043021 ! ribonucleoprotein complex binding + +[Term] +id: GO:0030520 +name: intracellular estrogen receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription)." [GOC:mah, GOC:signaling] +synonym: "estrogen receptor signaling pathway" BROAD [GOC:bf] +synonym: "estrogen receptor signalling pathway" BROAD [GOC:bf] +is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0030521 +name: androgen receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of an androgen binding to its receptor." [GOC:mah] +synonym: "androgen receptor signalling pathway" EXACT [] +is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0030522 +name: intracellular receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by a ligand binding to an receptor located within a cell." [GOC:bf, GOC:mah] +synonym: "intracellular receptor mediated signaling pathway" EXACT [] +synonym: "intracellular receptor-mediated signaling pathway" EXACT [] +synonym: "intracellular receptor-mediated signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0030523 +name: dihydrolipoamide S-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide." [EC:2.3.1.12, GOC:mah] +xref: EC:2.3.1.12 +is_a: GO:0016417 ! S-acyltransferase activity + +[Term] +id: GO:0030526 +name: granulocyte macrophage colony-stimulating factor receptor complex +namespace: cellular_component +def: "The heterodimeric receptor for granulocyte macrophage colony-stimulating factor." [GOC:mah] +synonym: "GM-CSF receptor complex" EXACT [GOC:vk] +synonym: "granulocyte macrophage colony stimulating factor receptor complex" EXACT [] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0030527 +name: structural constituent of chromatin +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of chromatin." [GOC:ai] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0000785 ! chromatin +relationship: occurs_in GO:0000785 ! chromatin + +[Term] +id: GO:0030528 +name: obsolete transcription regulator activity +namespace: molecular_function +def: "OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GOC:mah] +comment: This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "transcription regulator activity" EXACT [] +synonym: "transcriptional regulator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0140110 + +[Term] +id: GO:0030530 +name: obsolete heterogeneous nuclear ribonucleoprotein complex +namespace: cellular_component +def: "OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA." [ISBN:0198506732] +comment: This term was made because heterogeneous nuclear ribonucleoprotein is an experimental construct and does not correspond cleanly to a functional cellular entity. +synonym: "heterogeneous nuclear ribonucleoprotein" EXACT [] +synonym: "heterogeneous nuclear ribonucleoprotein complex" EXACT [] +synonym: "hnRNP" EXACT [] +xref: Wikipedia:Heterogeneous_ribonucleoprotein_particle +is_obsolete: true +consider: GO:0005681 +consider: GO:1990904 + +[Term] +id: GO:0030531 +name: obsolete small cytoplasmic ribonucleoprotein complex +namespace: cellular_component +def: "OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm." [GOC:krc, GOC:mah] +comment: This term was made obsolete because it was not clearly defined. +synonym: "scRNP" EXACT [] +synonym: "small cytoplasmic ribonucleoprotein" EXACT [] +synonym: "small cytoplasmic ribonucleoprotein complex" EXACT [] +is_obsolete: true +replaced_by: GO:1990904 + +[Term] +id: GO:0030532 +name: small nuclear ribonucleoprotein complex +namespace: cellular_component +def: "A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs." [GOC:krc, GOC:mah, ISBN:0879695897] +subset: goslim_pir +synonym: "small nuclear ribonucleoprotein" EXACT [] +synonym: "snRNP" EXACT [] +xref: Wikipedia:SnRNP +is_a: GO:0120114 ! Sm-like protein family complex +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0030533 +name: triplet codon-amino acid adaptor activity +namespace: molecular_function +def: "The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis." [GOC:hjd, GOC:mtg_MIT_16mar07, ISBN:0198506732] +comment: Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'. +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "transfer RNA" RELATED [] +synonym: "tRNA" RELATED [] +is_a: GO:0003729 ! mRNA binding +is_a: GO:0060090 ! molecular adaptor activity +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0030534 +name: adult behavior +namespace: biological_process +def: "Behavior in a fully developed and mature organism." [GOC:mah, ISBN:0877797099] +comment: See also the biological process term 'behavior ; GO:0007610'. +synonym: "adult behavioral response to stimulus" EXACT [] +synonym: "adult behaviour" EXACT [] +synonym: "adult behavioural response to stimulus" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0030535 +name: obsolete adult feeding behavior (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. Feeding behavior in a fully developed and mature organism, as described in insects." [GOC:go_curators, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "adult feeding behavior (sensu Insecta)" EXACT [] +is_obsolete: true +replaced_by: GO:0008343 + +[Term] +id: GO:0030536 +name: larval feeding behavior +namespace: biological_process +def: "Feeding behavior in a larval (immature) organism." [GOC:mah] +comment: See also the biological process term 'feeding behavior ; GO:0007631'. +synonym: "larval feeding behaviour" EXACT [] +is_a: GO:0007631 ! feeding behavior +is_a: GO:0030537 ! larval behavior + +[Term] +id: GO:0030537 +name: larval behavior +namespace: biological_process +alt_id: GO:0017037 +def: "Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics." [GOC:mah, ISBN:0877797099] +comment: See also the biological process term 'behavior ; GO:0007610'. +synonym: "larval behaviour" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0030538 +name: embryonic genitalia morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized." [GOC:bf] +synonym: "embryonic genital morphogenesis" RELATED [] +is_a: GO:0035112 ! genitalia morphogenesis +is_a: GO:0048562 ! embryonic organ morphogenesis + +[Term] +id: GO:0030539 +name: male genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888] +synonym: "male genital development" EXACT [] +is_a: GO:0048806 ! genitalia development +is_a: GO:0061458 ! reproductive system development +relationship: part_of GO:0046661 ! male sex differentiation + +[Term] +id: GO:0030540 +name: female genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure." [GOC:mah] +synonym: "female genital development" EXACT [] +is_a: GO:0048806 ! genitalia development +relationship: part_of GO:0046660 ! female sex differentiation + +[Term] +id: GO:0030541 +name: plasmid partitioning +namespace: biological_process +alt_id: GO:0030542 +def: "Any process in which plasmids are segregated or distributed into daughter cells upon cell division." [GOC:mah] +is_a: GO:0006276 ! plasmid maintenance + +[Term] +id: GO:0030543 +name: 2-micrometer plasmid partitioning +namespace: biological_process +def: "The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division." [GOC:mah] +is_a: GO:0030541 ! plasmid partitioning + +[Term] +id: GO:0030544 +name: Hsp70 protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size." [ISBN:0198506732] +is_a: GO:0031072 ! heat shock protein binding + +[Term] +id: GO:0030545 +name: receptor regulator activity +namespace: molecular_function +def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed." [GOC:ceb] +is_a: GO:0098772 ! molecular function regulator + +[Term] +id: GO:0030546 +name: signaling receptor activator activity +namespace: molecular_function +def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased." [GOC:ceb] +synonym: "receptor activator activity" BROAD [] +is_a: GO:0030545 ! receptor regulator activity + +[Term] +id: GO:0030547 +name: receptor inhibitor activity +namespace: molecular_function +def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased." [GOC:ceb] +is_a: GO:0030545 ! receptor regulator activity +relationship: negatively_regulates GO:0038023 ! signaling receptor activity +relationship: part_of GO:2000272 ! negative regulation of signaling receptor activity + +[Term] +id: GO:0030548 +name: acetylcholine receptor regulator activity +namespace: molecular_function +def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed." [GOC:mah] +is_a: GO:0099602 ! neurotransmitter receptor regulator activity +relationship: regulates GO:0015464 ! acetylcholine receptor activity + +[Term] +id: GO:0030549 +name: acetylcholine receptor activator activity +namespace: molecular_function +def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased." [GOC:mah] +is_a: GO:0030546 ! signaling receptor activator activity +is_a: GO:0030548 ! acetylcholine receptor regulator activity + +[Term] +id: GO:0030550 +name: acetylcholine receptor inhibitor activity +namespace: molecular_function +def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased." [GOC:mah] +is_a: GO:0030547 ! receptor inhibitor activity +is_a: GO:0030548 ! acetylcholine receptor regulator activity + +[Term] +id: GO:0030551 +name: cyclic nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:ai] +is_a: GO:0000166 ! nucleotide binding + +[Term] +id: GO:0030552 +name: cAMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate)." [GOC:ai] +synonym: "3',5' cAMP binding" EXACT [] +synonym: "3',5'-cAMP binding" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate binding" EXACT [] +synonym: "cyclic AMP binding" EXACT [] +is_a: GO:0030551 ! cyclic nucleotide binding +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0030553 +name: cGMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate)." [GOC:ai] +synonym: "3',5' cGMP binding" EXACT [] +synonym: "3',5'-cGMP binding" EXACT [] +synonym: "cyclic GMP binding" EXACT [] +is_a: GO:0030551 ! cyclic nucleotide binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0030554 +name: adenyl nucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate." [ISBN:0198506732] +subset: goslim_chembl +is_a: GO:0017076 ! purine nucleotide binding + +[Term] +id: GO:0030555 +name: RNA modification guide activity +namespace: molecular_function +def: "Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +subset: goslim_generic +subset: goslim_yeast +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0030556 +name: rRNA modification guide activity +namespace: molecular_function +def: "Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0019843 ! rRNA binding +is_a: GO:0030555 ! RNA modification guide activity + +[Term] +id: GO:0030557 +name: tRNA modification guide activity +namespace: molecular_function +def: "Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0000049 ! tRNA binding +is_a: GO:0030555 ! RNA modification guide activity + +[Term] +id: GO:0030558 +name: RNA pseudouridylation guide activity +namespace: molecular_function +def: "Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030555 ! RNA modification guide activity + +[Term] +id: GO:0030559 +name: rRNA pseudouridylation guide activity +namespace: molecular_function +def: "Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030556 ! rRNA modification guide activity +is_a: GO:0030558 ! RNA pseudouridylation guide activity + +[Term] +id: GO:0030560 +name: tRNA pseudouridylation guide activity +namespace: molecular_function +def: "Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030557 ! tRNA modification guide activity +is_a: GO:0030558 ! RNA pseudouridylation guide activity + +[Term] +id: GO:0030561 +name: RNA 2'-O-ribose methylation guide activity +namespace: molecular_function +def: "Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030555 ! RNA modification guide activity + +[Term] +id: GO:0030562 +name: rRNA 2'-O-ribose methylation guide activity +namespace: molecular_function +def: "Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030556 ! rRNA modification guide activity +is_a: GO:0030561 ! RNA 2'-O-ribose methylation guide activity + +[Term] +id: GO:0030563 +name: snRNA 2'-O-ribose methylation guide activity +namespace: molecular_function +def: "Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule." [PMID:11733745] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs. +is_a: GO:0030561 ! RNA 2'-O-ribose methylation guide activity +is_a: GO:0030566 ! snRNA modification guide activity + +[Term] +id: GO:0030564 +name: tRNA 2'-O-ribose methylation guide activity +namespace: molecular_function +def: "Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0030557 ! tRNA modification guide activity +is_a: GO:0030561 ! RNA 2'-O-ribose methylation guide activity + +[Term] +id: GO:0030565 +name: snRNA pseudouridylation guide activity +namespace: molecular_function +def: "Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule." [PMID:11733745] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs. +is_a: GO:0030558 ! RNA pseudouridylation guide activity +is_a: GO:0030566 ! snRNA modification guide activity + +[Term] +id: GO:0030566 +name: snRNA modification guide activity +namespace: molecular_function +def: "Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] +comment: Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. +is_a: GO:0017069 ! snRNA binding +is_a: GO:0030555 ! RNA modification guide activity + +[Term] +id: GO:0030567 +name: obsolete thrombin activator activity +namespace: molecular_function +def: "OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin." [GOC:mah] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "prothrombin activator activity" RELATED [GOC:dph, GOC:tb] +synonym: "thrombin activator activity" EXACT [] +is_obsolete: true +replaced_by: GO:0016504 + +[Term] +id: GO:0030568 +name: obsolete plasmin inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase plasmin." [GOC:mah] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function. +synonym: "plasmin inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004867 + +[Term] +id: GO:0030569 +name: obsolete chymotrypsin inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin." [GOC:mah] +comment: This term was made obsolete because it represents a regulator of an obsolete molecular function term. +synonym: "chymotrypsin inhibitor activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004867 + +[Term] +id: GO:0030570 +name: pectate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends." [EC:4.2.2.2] +synonym: "(1->4)-alpha-D-galacturonan lyase activity" EXACT [EC:4.2.2.2] +synonym: "alpha-1,4-D-endopolygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] +synonym: "endo-alpha-1,4-polygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] +synonym: "endogalacturonate transeliminase activity" EXACT [EC:4.2.2.2] +synonym: "endopectin methyltranseliminase activity" EXACT [EC:4.2.2.2] +synonym: "pectate transeliminase activity" EXACT [EC:4.2.2.2] +synonym: "pectic acid lyase activity" EXACT [EC:4.2.2.2] +synonym: "pectic acid transeliminase activity" EXACT [EC:4.2.2.2] +synonym: "pectic lyase activity" BROAD [EC:4.2.2.2] +synonym: "pectin trans-eliminase activity" BROAD [EC:4.2.2.2] +synonym: "PGA lyase activity" EXACT [EC:4.2.2.2] +synonym: "polygalacturonate lyase activity" EXACT [EC:4.2.2.2] +synonym: "polygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] +synonym: "polygalacturonic acid trans-eliminase activity" EXACT [EC:4.2.2.2] +synonym: "polygalacturonic transeliminase activity" EXACT [EC:4.2.2.2] +synonym: "PPase-N activity" EXACT [EC:4.2.2.2] +xref: EC:4.2.2.2 +xref: MetaCyc:4.2.2.2-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0030572 +name: phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group." [GOC:mb] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0030573 +name: bile acid catabolic process +namespace: biological_process +alt_id: GO:0019613 +def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] +synonym: "bile acid 7alpha-dehydroxylation pathway" NARROW [] +synonym: "bile acid breakdown" EXACT [] +synonym: "bile acid catabolism" EXACT [] +synonym: "bile acid degradation" EXACT [] +synonym: "cholate catabolic process" NARROW [] +xref: MetaCyc:7ALPHADEHYDROX-PWY +is_a: GO:0008206 ! bile acid metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0030574 +name: collagen catabolic process +namespace: biological_process +def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194] +synonym: "collagen breakdown" EXACT [] +synonym: "collagen catabolism" EXACT [] +synonym: "collagen degradation" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0032963 ! collagen metabolic process + +[Term] +id: GO:0030575 +name: nuclear body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins." [GOC:dph, GOC:jl, GOC:mah] +synonym: "nuclear body organisation" EXACT [] +synonym: "nuclear body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006997 ! nucleus organization + +[Term] +id: GO:0030576 +name: Cajal body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors." [GOC:mah, PMID:11031238] +comment: See also the cellular component term 'Cajal body ; GO:0015030'. +synonym: "Cajal body organisation" EXACT [] +synonym: "Cajal body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0030575 ! nuclear body organization + +[Term] +id: GO:0030577 +name: Lands organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies." [GOC:mah, PMID:10921892, PMID:8695863] +comment: See also the cellular component term 'Lands ; GO:0016606'. +synonym: "Lands organisation" EXACT [] +synonym: "Lands organization and biogenesis" RELATED [GOC:mah] +synonym: "LYSP100-associated nuclear domain organization" EXACT [GOC:mah] +is_a: GO:0030575 ! nuclear body organization + +[Term] +id: GO:0030578 +name: PML body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia)." [GOC:mah, PMID:10806078] +comment: See also the cellular component term 'PML body ; GO:0016605'. +synonym: "PML body organisation" EXACT [] +synonym: "PML body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0030575 ! nuclear body organization + +[Term] +id: GO:0030579 +name: ubiquitin-dependent SMAD protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome." [GOC:go_curators] +synonym: "ubiquitin-dependent SMAD protein breakdown" EXACT [] +synonym: "ubiquitin-dependent SMAD protein catabolism" EXACT [] +synonym: "ubiquitin-dependent SMAD protein degradation" EXACT [] +is_a: GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030580 +name: quinone cofactor methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1)." [GOC:mb] +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030581 +name: symbiont intracellular protein transport in host +namespace: biological_process +alt_id: GO:0051708 +def: "The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mb] +synonym: "host cell protein transport" EXACT [] +synonym: "intracellular protein transport in host" EXACT [] +synonym: "intracellular protein transport in other organism during symbiotic interaction" BROAD [GOC:dph] +synonym: "intracellular protein transport in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0015031 ! protein transport +is_a: GO:0051701 ! interaction with host +intersection_of: GO:0015031 ! protein transport +intersection_of: occurs_in GO:0043657 ! host cell +relationship: occurs_in GO:0043657 ! host cell + +[Term] +id: GO:0030582 +name: reproductive fruiting body development +namespace: biological_process +def: "The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores." [GOC:mah, GOC:mtg_sensu] +comment: This term describes the development of a fruiting body that is a spore-bearing organ. It is not intended to describe the development of myxococcal fruiting bodies. +synonym: "fruiting body formation" EXACT [] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0030583 +name: myxococcal fruiting body development +namespace: biological_process +alt_id: GO:0055084 +def: "The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure." [GOC:mtg_sensu, ISBN:0815316194, PMID:11121786] +comment: For example, as seen in myxobacterium. It is not intended to describe fruiting body development as is Dictyostelium. +synonym: "fruiting body development in cellular response to starvation" BROAD [] +synonym: "fruiting body development in response to starvation" BROAD [] +is_a: GO:0042594 ! response to starvation +is_a: GO:0044764 ! multi-organism cellular process + +[Term] +id: GO:0030584 +name: sporocarp development +namespace: biological_process +def: "The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea." [GOC:mah, GOC:mtg_sensu] +synonym: "fruiting body development" BROAD [] +is_a: GO:0030582 ! reproductive fruiting body development +disjoint_from: GO:0030587 ! sorocarp development + +[Term] +id: GO:0030585 +name: phosphoenolpyruvate carboxykinase (diphosphate) activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate." [EC:4.1.1.38, RHEA:22356] +synonym: "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.38] +synonym: "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.38] +synonym: "PEP carboxyphosphotransferase activity" EXACT [EC:4.1.1.38] +synonym: "PEPCTrP" RELATED [EC:4.1.1.38] +synonym: "phosphoenolpyruvate carboxykinase (pyrophosphate) activity" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvate carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvate carboxyphosphotransferase activity" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvate carboxytransphosphorylase activity" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.38] +synonym: "phosphoenolpyruvic carboxykinase (pyrophosphate)" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvic carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] +synonym: "phosphoenolpyruvic carboxytransphosphorylase activity" EXACT [EC:4.1.1.38] +synonym: "phosphopyruvate carboxykinase" BROAD [EC:4.1.1.38] +synonym: "phosphopyruvate carboxykinase (pyrophosphate)" EXACT [EC:4.1.1.38] +synonym: "phosphopyruvate carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] +xref: EC:4.1.1.38 +xref: KEGG_REACTION:R00346 +xref: MetaCyc:4.1.1.38-RXN +xref: RHEA:22356 +is_a: GO:0004611 ! phosphoenolpyruvate carboxykinase activity + +[Term] +id: GO:0030586 +name: [methionine synthase] reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+." [EC:1.16.1.8] +comment: Note that this was EC:2.1.1.135. +synonym: "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" RELATED [] +synonym: "[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity" EXACT [] +synonym: "methionine synthase cob(II)alamin reductase (methylating) activity" EXACT [EC:1.16.1.8] +synonym: "methionine synthase reductase activity" EXACT [EC:1.16.1.8] +synonym: "methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)" EXACT [EC:1.16.1.8] +synonym: "methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.8] +xref: EC:1.16.1.8 +xref: MetaCyc:2.1.1.135-RXN +xref: Reactome:R-HSA-3149518 "MTRR reduces cob(II)alamin to meCbl" +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0030587 +name: sorocarp development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640, PMID:4332228] +synonym: "fruiting body development" BROAD [] +synonym: "fruiting body formation" BROAD [] +synonym: "sorocarp biosynthesis" EXACT [] +synonym: "sorocarp formation" EXACT [] +is_a: GO:0090702 ! non-reproductive fruiting body development + +[Term] +id: GO:0030588 +name: pseudocleavage +namespace: biological_process +def: "Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis." [GOC:mah, PMID:10751167, PMID:30990821, PMID:7729583] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0030589 +name: pseudocleavage involved in syncytial blastoderm formation +namespace: biological_process +def: "Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu] +synonym: "pseudocleavage during syncytial blastoderm formation" RELATED [GOC:dph] +is_a: GO:0030588 ! pseudocleavage +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0030590 +name: first cell cycle pseudocleavage +namespace: biological_process +def: "A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms." [GOC:mtg_sensu, PMID:7729583] +is_a: GO:0030588 ! pseudocleavage + +[Term] +id: GO:0030591 +name: 2'-deoxyguanosine DNA ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form." [PMID:11592983] +synonym: "NAD DNA ADP-ribosyltransferase activity" BROAD [] +is_a: GO:0140294 ! NAD DNA ADP-ribosyltransferase activity + +[Term] +id: GO:0030592 +name: DNA ADP-ribosylation +namespace: biological_process +def: "The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA." [PMID:11592983, PMID:27471034, PMID:29361132, PMID:29520010] +is_a: GO:0006304 ! DNA modification +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16614 xsd:anyURI + +[Term] +id: GO:0030593 +name: neutrophil chemotaxis +namespace: biological_process +def: "The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding." [GOC:jl, ISBN:0198506732] +is_a: GO:0071621 ! granulocyte chemotaxis +is_a: GO:1990266 ! neutrophil migration + +[Term] +id: GO:0030594 +name: neurotransmitter receptor activity +namespace: molecular_function +def: "Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity." [GOC:jl, GOC:signaling] +comment: A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity' +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0042165 ! neurotransmitter binding + +[Term] +id: GO:0030595 +name: leukocyte chemotaxis +namespace: biological_process +def: "The movement of a leukocyte in response to an external stimulus." [GOC:add, GOC:jl] +synonym: "immune cell chemotaxis" EXACT [] +synonym: "leucocyte chemotaxis" EXACT [] +is_a: GO:0050900 ! leukocyte migration +is_a: GO:0060326 ! cell chemotaxis + +[Term] +id: GO:0030596 +name: alpha-L-rhamnosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides." [EC:3.2.1.40] +synonym: "alpha-L-rhamnosidase N" RELATED [EC:3.2.1.40] +synonym: "alpha-L-rhamnosidase T" RELATED [EC:3.2.1.40] +synonym: "alpha-L-rhamnoside rhamnohydrolase activity" EXACT [EC:3.2.1.40] +xref: EC:3.2.1.40 +xref: MetaCyc:3.2.1.40-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0030597 +name: RNA glycosylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule." [GOC:mah] +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0030598 +name: rRNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species." [EC:3.2.2.22, GOC:mah] +synonym: "gelonin" RELATED [EC:3.2.2.22] +synonym: "mirabilis antiviral protein" RELATED [EC:3.2.2.22] +synonym: "momorcochin-S" RELATED [EC:3.2.2.22] +synonym: "nigrin b" RELATED [EC:3.2.2.22] +synonym: "ribosomal ribonucleate N-glycosidase activity" EXACT [EC:3.2.2.22] +synonym: "ricin" RELATED [EC:3.2.2.22] +synonym: "RNA N-glycosidase activity" EXACT [EC:3.2.2.22] +synonym: "rRNA N-glycohydrolase activity" EXACT [EC:3.2.2.22] +synonym: "rRNA N-glycosidase activity" EXACT [] +synonym: "saporins" RELATED [EC:3.2.2.22] +xref: EC:3.2.2.22 +xref: MetaCyc:3.2.2.22-RXN +is_a: GO:0030597 ! RNA glycosylase activity +is_a: GO:0140102 ! catalytic activity, acting on a rRNA + +[Term] +id: GO:0030599 +name: pectinesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: pectin + n H2O = n methanol + pectate." [EC:3.1.1.11] +synonym: "pectase activity" EXACT [EC:3.1.1.11] +synonym: "pectin demethoxylase activity" EXACT [EC:3.1.1.11] +synonym: "pectin methoxylase activity" EXACT [EC:3.1.1.11] +synonym: "pectin methyl esterase activity" EXACT [EC:3.1.1.11] +synonym: "pectin methylesterase activity" EXACT [] +synonym: "pectin pectylhydrolase activity" EXACT [EC:3.1.1.11] +synonym: "pectinoesterase activity" EXACT [EC:3.1.1.11] +xref: EC:3.1.1.11 +xref: MetaCyc:PECTINESTERASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0030600 +name: feruloyl esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide." [EC:3.1.1.73] +synonym: "4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity" EXACT [EC:3.1.1.73] +synonym: "cinnAE" RELATED [EC:3.1.1.73] +synonym: "cinnamoyl ester hydrolase activity" EXACT [] +synonym: "FAE-I" RELATED [EC:3.1.1.73] +synonym: "FAE-II" RELATED [EC:3.1.1.73] +synonym: "FAE-III" RELATED [EC:3.1.1.73] +synonym: "FAEA" RELATED [EC:3.1.1.73] +synonym: "ferulic acid esterase activity" EXACT [EC:3.1.1.73] +synonym: "hemicellulase accessory" RELATED [EC:3.1.1.73] +synonym: "hydroxycinnamoyl esterase activity" EXACT [EC:3.1.1.73] +xref: EC:3.1.1.73 +xref: MetaCyc:3.1.1.73-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0030601 +name: obsolete aminopeptidase B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys." [EC:3.4.11.6] +comment: This term was made obsolete because it represents a gene product. +synonym: "aminopeptidase B activity" EXACT [] +synonym: "arginyl aminopeptidase activity" EXACT [] +synonym: "arylamidase II" RELATED [EC:3.4.11.6] +synonym: "Cl--activated arginine aminopeptidase activity" EXACT [EC:3.4.11.6] +synonym: "cytosol aminopeptidase IV" RELATED [EC:3.4.11.6] +synonym: "L-arginine aminopeptidase activity" EXACT [EC:3.4.11.6] +xref: EC:3.4.11.6 +xref: MetaCyc:3.4.11.6-RXN +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0030602 +name: obsolete chymosin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein." [EC:3.4.23.4] +comment: This term was made obsolete because it represents a gene product. +synonym: "chymosin activity" EXACT [] +synonym: "rennin" RELATED [EC:3.4.23.4] +synonym: "rennin (but this should be avoided since it leads to confusion with renin)" RELATED [EC:3.4.23.4] +xref: EC:3.4.23.4 +xref: MetaCyc:3.4.23.4-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0030603 +name: oxaloacetase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate." [EC:3.7.1.1, RHEA:24432] +synonym: "oxalacetic hydrolase activity" EXACT [EC:3.7.1.1] +synonym: "oxaloacetate acetylhydrolase activity" EXACT [EC:3.7.1.1] +xref: EC:3.7.1.1 +xref: KEGG_REACTION:R00338 +xref: MetaCyc:OXALOACETASE-RXN +xref: RHEA:24432 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0030604 +name: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH." [EC:1.1.1.267, RHEA:13717] +synonym: "1-deoxy-D-xylulose-5-phosphate isomeroreductase activity" EXACT [EC:1.1.1.267] +synonym: "1-deoxyxylulose-5-phosphate reductoisomerase activity" EXACT [EC:1.1.1.267] +synonym: "2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)" EXACT [EC:1.1.1.267] +synonym: "2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity" EXACT [EC:1.1.1.267] +synonym: "DOXP reductoisomerase activity" EXACT [] +synonym: "DXP-reductoisomerase activity" EXACT [EC:1.1.1.267] +xref: EC:1.1.1.267 +xref: KEGG_REACTION:R05688 +xref: MetaCyc:DXPREDISOM-RXN +xref: RHEA:13717 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0030611 +name: arsenate reductase activity +namespace: molecular_function +def: "Catalysis of the interconversion of arsenate and arsenite." [GOC:mah] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0030612 +name: arsenate reductase (thioredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin." [MetaCyc:RXN-10737] +xref: MetaCyc:RXN-10737 +is_a: GO:0030611 ! arsenate reductase activity + +[Term] +id: GO:0030613 +name: oxidoreductase activity, acting on phosphorus or arsenic in donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:mah] +synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors" NARROW [] +xref: EC:1.20 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0030614 +name: oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide." [GOC:mah] +synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor" EXACT [] +xref: EC:1.20.4 +is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors + +[Term] +id: GO:0030616 +name: obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity +namespace: molecular_function +def: "OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription." [GOC:hjd] +comment: This term was obsoleted because it is redundant with other terms. +synonym: "co-SMAD protein" RELATED [GOC:rl] +synonym: "common mediator SMAD protein" RELATED [GOC:rl] +synonym: "common partner SMAD protein" RELATED [GOC:rl] +synonym: "common-mediator SMAD protein" RELATED [GOC:rl] +synonym: "common-partner SMAD protein" RELATED [] +synonym: "TGF-beta receptor, common-partner cytoplasmic mediator activity" EXACT [] +synonym: "TGFbeta receptor, common-partner cytoplasmic mediator activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16202 xsd:anyURI +is_obsolete: true +consider: GO:0000981 +consider: GO:0003712 + +[Term] +id: GO:0030617 +name: obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity +namespace: molecular_function +def: "OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators." [PMID:9759503] +comment: This term was obsoleted because it represents the same activity as GO:0140416 ; DNA-binding transcription factor inhibitor activity', occurs_in cytosol. +synonym: "inhibitory SMAD protein" RELATED [] +synonym: "TGF-beta receptor, inhibitory cytoplasmic mediator activity" EXACT [] +synonym: "TGFbeta receptor, inhibitory cytoplasmic mediator activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16202 xsd:anyURI +is_obsolete: true +consider: GO:0140416 + +[Term] +id: GO:0030618 +name: obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity +namespace: molecular_function +def: "OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription." [GOC:hjd] +comment: This term was obsoleted because it is redundant with other terms. +synonym: "pathway restricted SMAD protein" RELATED [GOC:rl] +synonym: "pathway-restricted SMAD protein" RELATED [GOC:rl] +synonym: "pathway-specific SMAD protein" RELATED [] +synonym: "receptor regulated SMAD protein" RELATED [GOC:rl] +synonym: "receptor-regulated SMAD protein" RELATED [GOC:rl] +synonym: "TGF-beta receptor, pathway-specific cytoplasmic mediator activity" EXACT [] +synonym: "TGFbeta receptor, pathway-specific cytoplasmic mediator activity" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16202 xsd:anyURI +is_obsolete: true +consider: GO:0000981 +consider: GO:0003712 + +[Term] +id: GO:0030619 +name: U1 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA)." [GOC:mah] +comment: Note that this term may be useful for annotating other small nuclear RNAs (snRNAs). +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030620 +name: U2 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U2 small nuclear RNA (U2 snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030621 +name: U4 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U4 small nuclear RNA (U4 snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030622 +name: U4atac snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U4atac small nuclear RNA (U4atac snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030623 +name: U5 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U5 small nuclear RNA (U5 snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030624 +name: U6atac snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U6atac small nuclear RNA (U6atac snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030625 +name: U11 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U11 small nuclear RNA (U11 snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030626 +name: U12 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U12 small nuclear RNA (U12 snRNA)." [GOC:jl] +is_a: GO:0017069 ! snRNA binding + +[Term] +id: GO:0030627 +name: pre-mRNA 5'-splice site binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the pre-mRNA 5' splice site sequence." [GOC:jl] +synonym: "pre-mRNA 5' splice site binding" EXACT [] +is_a: GO:0036002 ! pre-mRNA binding + +[Term] +id: GO:0030628 +name: pre-mRNA 3'-splice site binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the pre-mRNA 3' splice site sequence." [GOC:jl] +synonym: "pre-mRNA 3' splice site binding" EXACT [] +is_a: GO:0036002 ! pre-mRNA binding + +[Term] +id: GO:0030629 +name: U6 snRNA 3'-end binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA)." [GOC:mah] +comment: Note that this term may be useful for annotating small nuclear RNAs (snRNAs). +synonym: "U6 snRNA 3' end binding" EXACT [] +is_a: GO:0017070 ! U6 snRNA binding + +[Term] +id: GO:0030631 +name: pyrrolysine incorporation +namespace: biological_process +def: "The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases." [PMID:11435424, PMID:17204561, RESID:AA0321] +synonym: "lysine methylamine methyltransferase cofactor adduct incorporation" EXACT [RESID:AA0321] +synonym: "monomethylamine methyltransferase cofactor lysine adduct incorporation" EXACT [] +xref: RESID:AA0321 +is_a: GO:0006451 ! translational readthrough + +[Term] +id: GO:0030632 +name: D-alanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid." [GOC:jsg, GOC:mah] +synonym: "D-alanine anabolism" EXACT [] +synonym: "D-alanine biosynthesis" EXACT [] +synonym: "D-alanine formation" EXACT [] +synonym: "D-alanine synthesis" EXACT [] +is_a: GO:0046145 ! D-alanine family amino acid biosynthetic process +is_a: GO:0046436 ! D-alanine metabolic process +is_a: GO:0046437 ! D-amino acid biosynthetic process + +[Term] +id: GO:0030633 +name: D-alanine family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids." [GOC:mah] +synonym: "D-alanine family amino acid breakdown" EXACT [] +synonym: "D-alanine family amino acid catabolism" EXACT [] +synonym: "D-alanine family amino acid degradation" EXACT [] +is_a: GO:0006524 ! alanine catabolic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process + +[Term] +id: GO:0030634 +name: carbon fixation by acetyl-CoA pathway +namespace: biological_process +def: "A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2)." [PMID:11607093] +synonym: "acetyl CoA pathway" RELATED [GOC:cjm, PMID:14602585] +synonym: "Ljungdahl-Wood pathway" EXACT [] +synonym: "reductive acetyl CoA pathway" EXACT [GOC:cjm, PMID:18801467] +xref: MetaCyc:CODH-PWY +xref: Wikipedia:Wood-Ljungdahl_pathway +is_a: GO:0006085 ! acetyl-CoA biosynthetic process +is_a: GO:0015977 ! carbon fixation +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0030635 +name: obsolete acetate derivative metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving derivatives of acetic acid." [GOC:mah] +comment: This term was made obsolete because it is an unnecessary grouping term, and has been replaced by terms to describe metabolism of specific compounds. +synonym: "acetate derivative metabolic process" EXACT [] +synonym: "acetate derivative metabolism" EXACT [] +is_obsolete: true +consider: GO:1900619 + +[Term] +id: GO:0030636 +name: obsolete acetate derivative biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid." [GOC:mah] +comment: This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds. +synonym: "acetate derivative anabolism" EXACT [] +synonym: "acetate derivative biosynthesis" EXACT [] +synonym: "acetate derivative biosynthetic process" EXACT [] +synonym: "acetate derivative formation" EXACT [] +synonym: "acetate derivative synthesis" EXACT [] +is_obsolete: true +consider: GO:1900620 + +[Term] +id: GO:0030637 +name: obsolete acetate derivative catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid." [GOC:ai] +comment: This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds. +synonym: "acetate derivative breakdown" EXACT [] +synonym: "acetate derivative catabolic process" EXACT [] +synonym: "acetate derivative catabolism" EXACT [] +synonym: "acetate derivative degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030638 +name: polyketide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps." [GOC:mah, ISBN:0198506732] +synonym: "polyketide metabolism" EXACT [] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0030639 +name: polyketide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps." [GOC:mah, ISBN:0198506732] +synonym: "polyketide anabolism" EXACT [] +synonym: "polyketide biosynthesis" EXACT [] +synonym: "polyketide formation" EXACT [] +synonym: "polyketide synthesis" EXACT [] +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0030640 +name: polyketide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps." [GOC:mah, ISBN:0198506732] +synonym: "polyketide breakdown" EXACT [] +synonym: "polyketide catabolism" EXACT [] +synonym: "polyketide degradation" EXACT [] +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0030641 +name: regulation of cellular pH +namespace: biological_process +def: "Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment." [GOC:dph, GOC:mah, GOC:tb] +synonym: "cellular hydrogen ion homeostasis" EXACT [GOC:dph, GOC:tb] +synonym: "proton homeostasis" EXACT [] +is_a: GO:0006885 ! regulation of pH +is_a: GO:0030004 ! cellular monovalent inorganic cation homeostasis + +[Term] +id: GO:0030642 +name: cellular sulfate ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell." [GOC:mah] +synonym: "sulphate ion homeostasis" BROAD [] +is_a: GO:0055063 ! sulfate ion homeostasis +is_a: GO:0072501 ! cellular divalent inorganic anion homeostasis + +[Term] +id: GO:0030643 +name: cellular phosphate ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell." [GOC:mah] +is_a: GO:0030320 ! cellular monovalent inorganic anion homeostasis +is_a: GO:0055062 ! phosphate ion homeostasis +is_a: GO:0072501 ! cellular divalent inorganic anion homeostasis +is_a: GO:0072502 ! cellular trivalent inorganic anion homeostasis + +[Term] +id: GO:0030644 +name: cellular chloride ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell." [GOC:mah] +is_a: GO:0030320 ! cellular monovalent inorganic anion homeostasis +is_a: GO:0055064 ! chloride ion homeostasis + +[Term] +id: GO:0030645 +name: glucose catabolic process to butyrate +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum." [ISBN:0198506732] +synonym: "butyrate fermentation" EXACT [] +synonym: "glucose fermentation to butyrate" EXACT [] +is_a: GO:0006007 ! glucose catabolic process +is_a: GO:0006113 ! fermentation +is_a: GO:1902705 ! hexose catabolic process to butyrate + +[Term] +id: GO:0030647 +name: aminoglycoside antibiotic metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin." [GOC:mah, ISBN:0198506732] +synonym: "aminoglycoside antibiotic metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process + +[Term] +id: GO:0030648 +name: aminoglycoside antibiotic biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin." [GOC:mah, ISBN:0198506732] +synonym: "aminoglycoside antibiotic anabolism" EXACT [] +synonym: "aminoglycoside antibiotic biosynthesis" EXACT [] +synonym: "aminoglycoside antibiotic formation" EXACT [] +synonym: "aminoglycoside antibiotic synthesis" EXACT [] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process + +[Term] +id: GO:0030649 +name: aminoglycoside antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin." [GOC:mah, ISBN:0198506732] +synonym: "aminoglycoside antibiotic breakdown" EXACT [] +synonym: "aminoglycoside antibiotic catabolism" EXACT [] +synonym: "aminoglycoside antibiotic degradation" EXACT [] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process + +[Term] +id: GO:0030650 +name: peptide antibiotic metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving peptides with antibiotic activity." [GOC:mah] +synonym: "peptide antibiotic metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0016999 ! antibiotic metabolic process + +[Term] +id: GO:0030651 +name: peptide antibiotic biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity." [GOC:mah] +synonym: "peptide antibiotic anabolism" EXACT [] +synonym: "peptide antibiotic biosynthesis" EXACT [] +synonym: "peptide antibiotic formation" EXACT [] +synonym: "peptide antibiotic synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030650 ! peptide antibiotic metabolic process +is_a: GO:0043043 ! peptide biosynthetic process + +[Term] +id: GO:0030652 +name: peptide antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity." [GOC:mah] +synonym: "peptide antibiotic breakdown" EXACT [] +synonym: "peptide antibiotic catabolism" EXACT [] +synonym: "peptide antibiotic degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030650 ! peptide antibiotic metabolic process +is_a: GO:0043171 ! peptide catabolic process + +[Term] +id: GO:0030653 +name: beta-lactam antibiotic metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins." [GOC:mah, ISBN:0198506732] +synonym: "beta-lactam antibiotic metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0044106 ! cellular amine metabolic process +is_a: GO:0072338 ! cellular lactam metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0030654 +name: beta-lactam antibiotic biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins." [GOC:mah, ISBN:0198506732] +synonym: "beta-lactam antibiotic anabolism" EXACT [] +synonym: "beta-lactam antibiotic biosynthesis" EXACT [] +synonym: "beta-lactam antibiotic formation" EXACT [] +synonym: "beta-lactam antibiotic synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process +is_a: GO:0072339 ! cellular lactam biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0030655 +name: beta-lactam antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins." [GOC:mah, ISBN:0198506732] +synonym: "beta-lactam antibiotic breakdown" EXACT [] +synonym: "beta-lactam antibiotic catabolism" EXACT [] +synonym: "beta-lactam antibiotic degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process +is_a: GO:0072340 ! cellular lactam catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0030656 +name: regulation of vitamin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:mah] +synonym: "regulation of vitamin metabolism" EXACT [] +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006766 ! vitamin metabolic process +relationship: regulates GO:0006766 ! vitamin metabolic process + +[Term] +id: GO:0030657 +name: obsolete regulation of coenzyme and prosthetic group metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "regulation of coenzyme and prosthetic group metabolic process" EXACT [] +is_obsolete: true +consider: GO:0051196 +consider: GO:0051199 + +[Term] +id: GO:0030658 +name: transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] +synonym: "constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "secretory vesicle membrane" BROAD [] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0030133 ! transport vesicle + +[Term] +id: GO:0030659 +name: cytoplasmic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] +is_a: GO:0012506 ! vesicle membrane +relationship: part_of GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0030660 +name: Golgi-associated vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] +synonym: "Golgi vesicle membrane" RELATED [] +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0005798 ! Golgi-associated vesicle + +[Term] +id: GO:0030661 +name: chitosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a chitosome." [GOC:mah] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0045009 ! chitosome + +[Term] +id: GO:0030662 +name: coated vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a coated vesicle." [GOC:mah] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0030135 ! coated vesicle + +[Term] +id: GO:0030663 +name: COPI-coated vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a COPI-coated vesicle." [GOC:mah] +synonym: "COPI coated vesicle membrane" EXACT [GOC:sl] +is_a: GO:0030660 ! Golgi-associated vesicle membrane +is_a: GO:0030662 ! coated vesicle membrane +relationship: part_of GO:0030137 ! COPI-coated vesicle + +[Term] +id: GO:0030665 +name: clathrin-coated vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-coated vesicle." [GOC:mah] +synonym: "clathrin coated vesicle membrane" NARROW [GOC:sl] +is_a: GO:0030662 ! coated vesicle membrane +relationship: part_of GO:0030136 ! clathrin-coated vesicle + +[Term] +id: GO:0030666 +name: endocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an endocytic vesicle." [GOC:mah] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0030139 ! endocytic vesicle + +[Term] +id: GO:0030667 +name: secretory granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] +synonym: "secretory vesicle membrane" BROAD [] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0030141 ! secretory granule + +[Term] +id: GO:0030668 +name: merozoite dense granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0020026 ! merozoite dense granule + +[Term] +id: GO:0030669 +name: clathrin-coated endocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-coated endocytic vesicle." [GOC:mah] +is_a: GO:0030665 ! clathrin-coated vesicle membrane +is_a: GO:0030666 ! endocytic vesicle membrane +relationship: part_of GO:0045334 ! clathrin-coated endocytic vesicle + +[Term] +id: GO:0030670 +name: phagocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a phagocytic vesicle." [GOC:mah] +synonym: "phagosome membrane" EXACT [GOC:mah] +is_a: GO:0030666 ! endocytic vesicle membrane +relationship: part_of GO:0045335 ! phagocytic vesicle + +[Term] +id: GO:0030671 +name: clathrin-coated phagocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-coated phagocytic vesicle." [GOC:mah] +is_a: GO:0030669 ! clathrin-coated endocytic vesicle membrane +is_a: GO:0030670 ! phagocytic vesicle membrane +relationship: part_of GO:0045336 ! clathrin-coated phagocytic vesicle + +[Term] +id: GO:0030672 +name: synaptic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a synaptic vesicle." [GOC:mah] +subset: goslim_synapse +is_a: GO:0099501 ! exocytic vesicle membrane +relationship: part_of GO:0008021 ! synaptic vesicle + +[Term] +id: GO:0030673 +name: axolemma +namespace: cellular_component +def: "The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness." [http://www.medik.sk/clanky/bio_jun.htm, ISBN:0124325653] +synonym: "axonal membrane" EXACT [GOC:vk] +xref: NIF_Subcellular:sao250772229 +xref: Wikipedia:Axolemma +is_a: GO:0032589 ! neuron projection membrane +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0030674 +name: protein-macromolecule adaptor activity +namespace: molecular_function +def: "The binding activity of a protein that brings together another macromolecule in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid." [GOC:bf, GOC:mah, GOC:vw] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "protein binding, bridging" EXACT [] +synonym: "protein-protein adaptor" NARROW [] +is_a: GO:0005515 ! protein binding +is_a: GO:0060090 ! molecular adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18655 xsd:anyURI + +[Term] +id: GO:0030676 +name: Rac guanyl-nucleotide exchange factor activity +namespace: molecular_function +def: "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] +xref: Reactome:R-HSA-399938 "Activation of Rac1 by FARP2" +xref: Reactome:R-HSA-428535 "Activation of RAC1 by SOS" +xref: Reactome:R-HSA-9032798 "DOCK3 activates RAC1" +xref: Reactome:R-HSA-9033292 "NTRK2 and CDK5 promote activation of RAC1 by TIAM1" +xref: Reactome:R-HSA-9619803 "p-S516-ARHGEF7 activates RAC1" +is_a: GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +is_a: GO:0048365 ! Rac GTPase binding + +[Term] +id: GO:0030677 +name: ribonuclease P complex +namespace: cellular_component +def: "A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs." [GOC:mah, PMID:12045094] +comment: Note that chloroplasts possess a complex that is called 'RNase P' because it catalyzes pre-tRNA cleavage, but the chloroplast complex appears not to contain RNA. +subset: goslim_pir +synonym: "RNase P complex" EXACT [] +is_a: GO:1902555 ! endoribonuclease complex +is_a: GO:1990904 ! ribonucleoprotein complex + +[Term] +id: GO:0030678 +name: mitochondrial ribonuclease P complex +namespace: cellular_component +def: "A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species, but the complex often contains a single RNA molecule and a single protein molecule." [GOC:mah, PMID:12045094] +synonym: "mitochondrial RNase P complex" EXACT [] +is_a: GO:0030677 ! ribonuclease P complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0030677 ! ribonuclease P complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0030679 +name: cyanelle ribonuclease P complex +namespace: cellular_component +def: "A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules." [GOC:mah, PMID:12045094] +synonym: "cyanelle RNase P complex" EXACT [] +is_a: GO:0030681 ! multimeric ribonuclease P complex +intersection_of: GO:0030677 ! ribonuclease P complex +intersection_of: part_of GO:0009842 ! cyanelle +relationship: part_of GO:0009842 ! cyanelle + +[Term] +id: GO:0030680 +name: dimeric ribonuclease P complex +namespace: cellular_component +def: "A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species." [GOC:mah, PMID:12045094] +synonym: "dimeric RNase P complex" EXACT [] +is_a: GO:0030677 ! ribonuclease P complex + +[Term] +id: GO:0030681 +name: multimeric ribonuclease P complex +namespace: cellular_component +def: "A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species." [GOC:mah, PMID:11142368, PMID:12045094] +synonym: "multimeric RNase P complex" EXACT [] +is_a: GO:0030677 ! ribonuclease P complex + +[Term] +id: GO:0030682 +name: mitigation of host defenses by symbiont +namespace: biological_process +alt_id: GO:0044413 +alt_id: GO:0044415 +alt_id: GO:0051807 +alt_id: GO:0051832 +alt_id: GO:0051834 +def: "A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "avoidance of defenses of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "avoidance of defenses of other organism involved in symbiotic interaction" NARROW [] +synonym: "avoidance of host defences" NARROW [] +synonym: "avoidance of host defenses" NARROW [] +synonym: "evasion of host defence response" NARROW [] +synonym: "evasion of other organism defence response" NARROW [] +synonym: "evasion or tolerance of defense response of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "evasion or tolerance of defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "evasion or tolerance of defenses of other organism" RELATED [] +synonym: "evasion or tolerance of defenses of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "evasion or tolerance of defenses of other organism involved in symbiotic interaction" RELATED [] +synonym: "evasion or tolerance of host defense response" NARROW [] +synonym: "evasion or tolerance of host defenses" RELATED [] +is_a: GO:0052200 ! response to host defenses + +[Term] +id: GO:0030683 +name: mitigation of host immune response by virus +namespace: biological_process +alt_id: GO:0019052 +alt_id: GO:0019053 +def: "A process by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mah, GOC:pk] +synonym: "evasion by virus of host immune response" NARROW [GOC:bf, GOC:bm, GOC:jl] +synonym: "evasion or tolerance by virus of host immune response" RELATED [] +synonym: "inhibition of extracellular antiviral response" EXACT [] +synonym: "mitigation by virus of host immune response" EXACT [] +synonym: "negative regulation by virus of extracellular antiviral response" EXACT [] +synonym: "negative regulation by virus of intracellular antiviral response" EXACT [] +synonym: "negative regulation of host extracellular antiviral response by virus" EXACT [] +synonym: "negative regulation of host intracellular antiviral response by virus" EXACT [] +synonym: "suppression by virus of host extracellular antiviral response" EXACT [] +synonym: "suppression by virus of host immune response" NARROW [GOC:bf] +synonym: "suppression by virus of host intracellular antiviral response" EXACT [] +synonym: "suppression of host extracellular antiviral response by virus" EXACT [] +synonym: "suppression of host intracellular antiviral response by virus" EXACT [] +synonym: "viral inhibition of intracellular antiviral response" EXACT [] +is_a: GO:0019049 ! mitigation of host defenses by virus +is_a: GO:0050690 ! regulation of defense response to virus by virus + +[Term] +id: GO:0030684 +name: preribosome +namespace: cellular_component +def: "Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis." [PMID:10567516] +subset: goslim_pir +is_a: GO:1990904 ! ribonucleoprotein complex + +[Term] +id: GO:0030685 +name: nucleolar preribosome +namespace: cellular_component +def: "Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis." [PMID:10567516] +is_a: GO:0030684 ! preribosome +intersection_of: GO:0030684 ! preribosome +intersection_of: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0030686 +name: 90S preribosome +namespace: cellular_component +def: "A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins." [GOC:krc, GOC:vw, PMID:12150911, PMID:12957375, PMID:15120992] +is_a: GO:0030684 ! preribosome +relationship: has_part GO:0034455 ! t-UTP complex + +[Term] +id: GO:0030687 +name: preribosome, large subunit precursor +namespace: cellular_component +def: "A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit." [PMID:10567516] +comment: Note that this complex is 66S in Saccharomyces. +synonym: "66S preribosome" NARROW [] +is_a: GO:0030684 ! preribosome + +[Term] +id: GO:0030688 +name: preribosome, small subunit precursor +namespace: cellular_component +def: "A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit." [PMID:10567516] +comment: Note that this complex is 43S in Saccharomyces. +synonym: "43S preribosome" NARROW [] +is_a: GO:0030684 ! preribosome + +[Term] +id: GO:0030689 +name: Noc complex +namespace: cellular_component +def: "Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis." [PMID:12446671] +comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the definition uses Saccharomyces gene product names because this complex has only been described in Saccharomyces cerevisiae and no other names have yet arisen; the term nevertheless can be used for analogous complexes in other eukaryotes, and the definition can be changed if better wording is found. +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0030690 +name: Noc1p-Noc2p complex +namespace: cellular_component +def: "A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis." [PMID:12446671] +comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +is_a: GO:0030689 ! Noc complex +relationship: part_of GO:0030686 ! 90S preribosome +relationship: part_of GO:0030687 ! preribosome, large subunit precursor + +[Term] +id: GO:0030691 +name: Noc2p-Noc3p complex +namespace: cellular_component +def: "A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis." [PMID:12446671] +comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +is_a: GO:0030689 ! Noc complex +relationship: part_of GO:0030687 ! preribosome, large subunit precursor + +[Term] +id: GO:0030692 +name: Noc4p-Nop14p complex +namespace: cellular_component +def: "A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis." [PMID:12446671] +comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654' and/or 'nuclear pore ; GO:0005643'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +synonym: "Nop7 complex" EXACT [GOC:jh, GOC:mah] +synonym: "Nop7 subcomplex" EXACT [GOC:jh, GOC:mah, PMID:18448671] +is_a: GO:0030689 ! Noc complex +relationship: part_of GO:0030686 ! 90S preribosome +relationship: part_of GO:0030688 ! preribosome, small subunit precursor + +[Term] +id: GO:0030693 +name: obsolete caspase activity +namespace: molecular_function +alt_id: GO:0004199 +def: "OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue." [PMID:10872455] +comment: This term was made obsolete because it represents a gene product. +synonym: "caspase activity" EXACT [] +synonym: "caspase-1 activity" NARROW [] +synonym: "caspase-10 activity" NARROW [] +synonym: "caspase-2 activity" NARROW [] +synonym: "caspase-3 activity" NARROW [] +synonym: "caspase-4 activity" NARROW [] +synonym: "caspase-5 activity" NARROW [] +synonym: "caspase-6 activity" NARROW [] +synonym: "caspase-7 activity" NARROW [] +synonym: "caspase-8 activity" NARROW [] +synonym: "caspase-9 activity" NARROW [] +synonym: "effector caspase activity" NARROW [] +synonym: "signaling (initiator) caspase activity" NARROW [] +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0030694 +name: bacterial-type flagellum basal body, rod +namespace: cellular_component +def: "The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings." [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] +synonym: "flagellar basal body, rod" EXACT [] +synonym: "flagellin-based flagellum basal body, rod" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009425 ! bacterial-type flagellum basal body + +[Term] +id: GO:0030695 +name: GTPase regulator activity +namespace: molecular_function +alt_id: GO:0005083 +def: "Modulates the rate of GTP hydrolysis by a GTPase." [GOC:mah] +synonym: "small GTPase regulator activity" RELATED [] +synonym: "small GTPase regulatory/interacting protein activity" RELATED [] +is_a: GO:0060589 ! nucleoside-triphosphatase regulator activity +relationship: regulates GO:0003924 ! GTPase activity + +[Term] +id: GO:0030696 +name: tRNA (m5U54) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule." [ISBN:1555811337] +comment: Note that the term name mentions a specific position within a tRNA because no other names have yet arisen for this activity, and because the position is conserved in nearly all tRNAs. The term nevertheless can be used for activities that methylase an analogous residue at a position other than 54, if such is found, and synonyms that mention positions applicable to other tRNAs or species may also be added. +synonym: "RUMT" EXACT [] +is_a: GO:0016300 ! tRNA (uracil) methyltransferase activity + +[Term] +id: GO:0030697 +name: S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity +namespace: molecular_function +alt_id: GO:0009021 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes." [GOC:hjd, ISBN:1555811337] +synonym: "M5U-methyltransferase activity" EXACT [EC:2.1.1.35] +synonym: "ribothymidyl synthase activity" BROAD [EC:2.1.1.35] +synonym: "RUMT" BROAD [] +synonym: "RUMT activity" EXACT [EC:2.1.1.35] +synonym: "S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity" EXACT [EC:2.1.1.35] +synonym: "transfer RNA uracil 5-methyltransferase activity" EXACT [EC:2.1.1.35] +synonym: "transfer RNA uracil methylase activity" EXACT [EC:2.1.1.35] +synonym: "tRNA (uracil-5-)-methyltransferase activity" EXACT [] +synonym: "tRNA uracil 5-methyltransferase activity" EXACT [EC:2.1.1.35] +synonym: "tRNA:m(5)U54-methyltransferase activity" EXACT [EC:2.1.1.35] +synonym: "tRNA:m5U54-methyltransferase activity" EXACT [EC:2.1.1.35] +xref: EC:2.1.1.35 +xref: MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0030696 ! tRNA (m5U54) methyltransferase activity + +[Term] +id: GO:0030698 +name: 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria." [GOC:hjd, ISBN:1555811337] +synonym: "RUMT" BROAD [] +is_a: GO:0030696 ! tRNA (m5U54) methyltransferase activity +is_a: GO:0042083 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity + +[Term] +id: GO:0030699 +name: glycine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin." [EC:1.21.4.2, RHEA:12232] +synonym: "acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)" EXACT [EC:1.21.4.2] +xref: EC:1.21.4.2 +xref: KEGG_REACTION:R07226 +xref: MetaCyc:RXN-7566 +xref: RHEA:12232 +is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor + +[Term] +id: GO:0030700 +name: glycine reductase complex +namespace: cellular_component +def: "Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C." [GOC:mah, PMID:2018775] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glycine reductase activity ; GO:0030699'. +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0030701 +name: NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]." [EC:2.4.2.37] +synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.37] +synonym: "NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity" EXACT [EC:2.4.2.37] +synonym: "NAD--azoferredoxin (ADP-ribose)transferase activity" EXACT [EC:2.4.2.37] +synonym: "NAD-azoferredoxin (ADPribose)transferase activity" EXACT [EC:2.4.2.37] +synonym: "NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity" EXACT [] +xref: EC:2.4.2.37 +xref: MetaCyc:2.4.2.37-RXN +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0030703 +name: eggshell formation +namespace: biological_process +def: "Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration." [GOC:mtg_sensu, ISBN:0879694238, PMID:10822261] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0030704 +name: vitelline membrane formation +namespace: biological_process +def: "Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg." [ISBN:0879694238] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0035803 ! egg coat formation +is_a: GO:0085029 ! extracellular matrix assembly + +[Term] +id: GO:0030705 +name: cytoskeleton-dependent intracellular transport +namespace: biological_process +def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0030706 +name: germarium-derived oocyte differentiation +namespace: biological_process +def: "The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "oocyte cell differentiation" RELATED [] +is_a: GO:0009994 ! oocyte differentiation +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation + +[Term] +id: GO:0030707 +name: ovarian follicle cell development +namespace: biological_process +def: "The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] +is_a: GO:0002066 ! columnar/cuboidal epithelial cell development +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0030708 +name: germarium-derived female germ-line cyst encapsulation +namespace: biological_process +def: "Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11591336] +is_a: GO:0048139 ! female germ-line cyst encapsulation +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0030709 +name: border follicle cell delamination +namespace: biological_process +def: "The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration." [PMID:10822261] +synonym: "border cell delamination" BROAD [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0060232 ! delamination +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0030710 +name: regulation of border follicle cell delamination +namespace: biological_process +def: "Any process that regulates the frequency, rate or extent of border cell delamination." [PMID:10822261] +synonym: "regulation of border cell delamination" BROAD [] +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:1905879 ! regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030709 ! border follicle cell delamination +relationship: regulates GO:0030709 ! border follicle cell delamination + +[Term] +id: GO:0030711 +name: positive regulation of border follicle cell delamination +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of border cell delamination." [PMID:10822261] +synonym: "activation of border follicle cell delamination" NARROW [] +synonym: "positive regulation of border cell delamination" BROAD [] +synonym: "stimulation of border follicle cell delamination" NARROW [] +synonym: "up regulation of border follicle cell delamination" EXACT [] +synonym: "up-regulation of border follicle cell delamination" EXACT [] +synonym: "upregulation of border follicle cell delamination" EXACT [] +is_a: GO:0030710 ! regulation of border follicle cell delamination +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:1905881 ! positive regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030709 ! border follicle cell delamination +relationship: positively_regulates GO:0030709 ! border follicle cell delamination + +[Term] +id: GO:0030712 +name: negative regulation of border follicle cell delamination +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of border cell delamination." [PMID:10822261] +synonym: "down regulation of border follicle cell delamination" EXACT [] +synonym: "down-regulation of border follicle cell delamination" EXACT [] +synonym: "downregulation of border follicle cell delamination" EXACT [] +synonym: "inhibition of border follicle cell delamination" NARROW [] +synonym: "negative regulation of border cell delamination" BROAD [] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0030710 ! regulation of border follicle cell delamination +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:1905880 ! negative regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030709 ! border follicle cell delamination +relationship: negatively_regulates GO:0030709 ! border follicle cell delamination + +[Term] +id: GO:0030713 +name: ovarian follicle cell stalk formation +namespace: biological_process +def: "Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0030714 +name: anterior/posterior axis specification, follicular epithelium +namespace: biological_process +def: "Polarization of the follicle cells of an insect ovary along the anterior/posterior axis." [GOC:bf] +synonym: "anterior/posterior axis determination, follicular epithelium" EXACT [GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009798 ! axis specification +is_a: GO:0016334 ! establishment or maintenance of polarity of follicular epithelium +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0030707 ! ovarian follicle cell development + +[Term] +id: GO:0030715 +name: oocyte growth in germarium-derived egg chamber +namespace: biological_process +def: "The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] +is_a: GO:0001555 ! oocyte growth +relationship: part_of GO:0007295 ! growth of a germarium-derived egg chamber + +[Term] +id: GO:0030716 +name: oocyte fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +synonym: "oocyte cell fate determination" EXACT [] +is_a: GO:0001709 ! cell fate determination + +[Term] +id: GO:0030717 +name: oocyte karyosome formation +namespace: biological_process +def: "The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome." [PMID:11700288, PMID:18039935] +is_a: GO:0061988 ! karyosome formation +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0030718 +name: germ-line stem cell population maintenance +namespace: biological_process +def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] +is_a: GO:0019827 ! stem cell population maintenance + +[Term] +id: GO:0030719 +name: P granule organization +namespace: biological_process +alt_id: GO:0048114 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes." [PMID:10851135, PMID:770367] +synonym: "P granule organization and biogenesis" RELATED [] +synonym: "polar granule organisation" EXACT [] +synonym: "polar granule organization and biogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006996 ! organelle organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007315 ! pole plasm assembly + +[Term] +id: GO:0030720 +name: oocyte localization involved in germarium-derived egg chamber formation +namespace: biological_process +def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356] +synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT [] +synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT [] +synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah] +synonym: "oocyte localization during germarium-derived egg chamber formation" RELATED [GOC:dph, GOC:tb] +synonym: "oocyte localization during oogenesis" RELATED [] +synonym: "oocyte positioning during oogenesis" NARROW [] +synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT [] +synonym: "oogenesis, oocyte localization" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051674 ! localization of cell +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation + +[Term] +id: GO:0030721 +name: spectrosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome." [PMID:11131529] +synonym: "spectrosome organisation" EXACT [] +synonym: "spectrosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0030723 +name: ovarian fusome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions." [GOC:dph, GOC:jl, GOC:mah, ISBN:0879694238] +synonym: "ovarian fusome organisation" EXACT [] +synonym: "ovarian fusome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045478 ! fusome organization +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation + +[Term] +id: GO:0030724 +name: testicular fusome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome." [GOC:dph, GOC:jl, GOC:mah, ISBN:0879694238] +synonym: "testicular fusome organisation" EXACT [] +synonym: "testicular fusome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045478 ! fusome organization +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0030725 +name: germline ring canal formation +namespace: biological_process +def: "Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts." [ISBN:0879694238] +synonym: "ring canal formation" BROAD [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0043063 ! intercellular bridge organization + +[Term] +id: GO:0030726 +name: male germline ring canal formation +namespace: biological_process +def: "Formation of the intercellular bridges that connect the germ-line cells of a male cyst." [ISBN:0879694238] +synonym: "spermatocyte ring canal formation" NARROW [] +synonym: "testicular ring canal formation" NARROW [] +is_a: GO:0030725 ! germline ring canal formation +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0030727 +name: germarium-derived female germ-line cyst formation +namespace: biological_process +def: "Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10370240, PMID:9442902] +synonym: "germarium-derived female germline cyst formation" EXACT [] +is_a: GO:0048135 ! female germ-line cyst formation +relationship: part_of GO:0007293 ! germarium-derived egg chamber formation + +[Term] +id: GO:0030728 +name: ovulation +namespace: biological_process +def: "The release of a mature ovum/oocyte from an ovary." [GOC:bf, ISBN:0878932437] +xref: Wikipedia:Ovulation +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007292 ! female gamete generation + +[Term] +id: GO:0030729 +name: acetoacetate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+)." [EC:6.2.1.16, RHEA:16117] +synonym: "acetoacetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.16] +synonym: "acetoacetyl-CoA synthetase activity" EXACT [] +xref: EC:6.2.1.16 +xref: KEGG_REACTION:R01357 +xref: MetaCyc:ACETOACETATE--COA-LIGASE-RXN +xref: Reactome:R-HSA-5694494 "AACS ligates CoA-SH to ACA, forming ACA-CoA" +xref: RHEA:16117 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0030730 +name: sequestering of triglyceride +namespace: biological_process +def: "The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system." [GOC:mah, ISBN:0198506732] +synonym: "retention of triacylglycerol" EXACT [] +synonym: "retention of triglyceride" EXACT [] +synonym: "sequestering of triacylglycerol" EXACT [] +synonym: "sequestration of triacylglycerol" EXACT [] +synonym: "sequestration of triglyceride" EXACT [] +synonym: "storage of triacylglycerol" EXACT [] +synonym: "storage of triglyceride" EXACT [] +synonym: "triacylglycerol retention" EXACT [] +synonym: "triacylglycerol sequestering" EXACT [] +synonym: "triacylglycerol sequestration" EXACT [] +synonym: "triacylglycerol storage" EXACT [] +synonym: "triglyceride retention" EXACT [] +synonym: "triglyceride sequestering" EXACT [] +synonym: "triglyceride sequestration" EXACT [] +synonym: "triglyceride storage" EXACT [] +is_a: GO:0019915 ! lipid storage + +[Term] +id: GO:0030731 +name: guanidinoacetate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+)." [EC:2.1.1.2, RHEA:10656] +synonym: "GA methylpherase activity" EXACT [EC:2.1.1.2] +synonym: "guanidinoacetate methyltransferase activity" EXACT [EC:2.1.1.2] +synonym: "guanidinoacetate transmethylase activity" EXACT [EC:2.1.1.2] +synonym: "guanidoacetate methyltransferase activity" EXACT [EC:2.1.1.2] +synonym: "methionine-guanidinoacetic transmethylase activity" EXACT [EC:2.1.1.2] +synonym: "S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity" EXACT [EC:2.1.1.2] +xref: EC:2.1.1.2 +xref: KEGG_REACTION:R01883 +xref: MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN +xref: RHEA:10656 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030732 +name: methionine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine." [EC:2.1.1.12] +synonym: "methionine methyltransferase activity" EXACT [EC:2.1.1.12] +synonym: "S-adenosyl methionine:methionine methyl transferase activity" EXACT [EC:2.1.1.12] +synonym: "S-adenosyl-L-methionine:L-methionine S-methyltransferase activity" EXACT [EC:2.1.1.12] +synonym: "S-adenosylmethionine transmethylase activity" EXACT [EC:2.1.1.12] +synonym: "S-adenosylmethionine-methionine methyltransferase activity" EXACT [EC:2.1.1.12] +xref: EC:2.1.1.12 +xref: MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN +xref: RHEA:13761 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030733 +name: fatty acid O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester." [EC:2.1.1.15] +synonym: "fatty acid methyltransferase activity" EXACT [EC:2.1.1.15] +synonym: "fatty-acid O-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity" EXACT [EC:2.1.1.15] +xref: EC:2.1.1.15 +xref: MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030734 +name: polysaccharide O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units." [EC:2.1.1.18] +synonym: "acylpolysacharide 6-methyltransferase activity" EXACT [EC:2.1.1.18] +synonym: "polysaccharide methyltransferase activity" EXACT [EC:2.1.1.18] +synonym: "S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity" EXACT [EC:2.1.1.18] +xref: EC:2.1.1.18 +xref: MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030735 +name: carnosine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+)." [EC:2.1.1.22, RHEA:14205] +synonym: "S-adenosyl-L-methionine:carnosine N-methyltransferase activity" EXACT [EC:2.1.1.22] +xref: EC:2.1.1.22 +xref: KEGG_REACTION:R02144 +xref: MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-8876789 "CARNMT1 methylates CARN to Anserine" +xref: RHEA:14205 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030736 +name: phenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+)." [EC:2.1.1.25, RHEA:14809] +synonym: "PMT" RELATED [EC:2.1.1.25] +synonym: "S-adenosyl-L-methionine:phenol O-methyltransferase activity" EXACT [EC:2.1.1.25] +xref: EC:2.1.1.25 +xref: KEGG_REACTION:R01239 +xref: MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN +xref: RHEA:14809 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030737 +name: iodophenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.26, RHEA:14313] +synonym: "S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity" EXACT [EC:2.1.1.26] +xref: EC:2.1.1.26 +xref: KEGG_REACTION:R03746 +xref: MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN +xref: RHEA:14313 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030738 +name: tyramine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.27, RHEA:14865] +synonym: "DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)" EXACT [EC:2.1.1.27] +synonym: "S-adenosyl-L-methionine:tyramine N-methyltransferase activity" EXACT [EC:2.1.1.27] +synonym: "S-adenosyl-methionine:tyramine N-methyltransferase activity" EXACT [EC:2.1.1.27] +synonym: "tyramine methylpherase activity" EXACT [EC:2.1.1.27] +xref: EC:2.1.1.27 +xref: KEGG_REACTION:R02384 +xref: MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN +xref: RHEA:14865 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030739 +name: O-demethylpuromycin O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin." [EC:2.1.1.38] +synonym: "O-demethylpuromycin methyltransferase activity" EXACT [EC:2.1.1.38] +synonym: "S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity" EXACT [EC:2.1.1.38] +xref: EC:2.1.1.38 +xref: MetaCyc:2.1.1.38-RXN +xref: RHEA:22280 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030740 +name: inositol 3-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.39, RHEA:18877] +synonym: "inositol L-1-methyltransferase activity" EXACT [EC:2.1.1.39] +synonym: "myo-inositol 1-methyltransferase activity" RELATED [EC:2.1.1.39] +synonym: "myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)" EXACT [EC:2.1.1.39] +synonym: "myo-inositol 1-O-methyltransferase activity" RELATED [EC:2.1.1.39] +synonym: "S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity" EXACT [EC:2.1.1.39] +synonym: "S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity" EXACT [EC:2.1.1.39] +synonym: "S-adenosylmethionine:myo-inositol 1-methyltransferase activity" EXACT [EC:2.1.1.39] +xref: EC:2.1.1.39 +xref: KEGG_REACTION:R01189 +xref: MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN +xref: RHEA:18877 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030741 +name: inositol 1-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.40, RHEA:17565] +synonym: "inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)" EXACT [EC:2.1.1.40] +synonym: "inositol 3-O-methyltransferase activity" RELATED [EC:2.1.1.40] +synonym: "inositol D-1-methyltransferase activity" EXACT [EC:2.1.1.40] +synonym: "myo-inositol 3-O-methyltransferase activity" RELATED [EC:2.1.1.40] +synonym: "S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity" EXACT [EC:2.1.1.40] +synonym: "S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity" EXACT [EC:2.1.1.40] +synonym: "S-adenosylmethionine:myo-inositol 3-methyltransferase activity" RELATED [EC:2.1.1.40] +xref: EC:2.1.1.40 +xref: KEGG_REACTION:R01188 +xref: MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN +xref: RHEA:17565 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030742 +name: GTP-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state." [GOC:go_curators, GOC:krc] +comment: This term may be used to annotate both partners in a GTP-dependent binding interaction, both the GTP-bound protein and the protein(s) which interact with it. +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0030743 +name: rRNA (adenosine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine." [EC:2.1.1.230] +synonym: "ribosomal ribonucleate adenosine 2'-methyltransferase activity" EXACT [EC:2.1.1.230] +synonym: "RNA-pentose methylase activity" RELATED [] +synonym: "rRNA adenosine 2'-methylase activity" EXACT [EC:2.1.1.230] +synonym: "S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity" EXACT [EC:2.1.1.230] +synonym: "thiostrepton-resistance methylase activity" NARROW [EC:2.1.1.230] +xref: EC:2.1.1.230 +xref: MetaCyc:2.1.1.66-RXN +xref: RHEA:43212 +is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity + +[Term] +id: GO:0030744 +name: luteolin O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.42, RHEA:14589] +synonym: "luteolin 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "luteolin methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "o-dihydric phenol meta-O-methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "o-dihydric phenol methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "o-diphenol m-O-methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] +synonym: "S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] +xref: EC:2.1.1.42 +xref: KEGG_REACTION:R03587 +xref: MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN +xref: RHEA:14589 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030745 +name: dimethylhistidine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine." [EC:2.1.1.44] +synonym: "dimethylhistidine methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "histidine-alpha-N-methyltransferase activity" BROAD [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity" EXACT [EC:2.1.1.44] +xref: EC:2.1.1.44 +xref: KEGG_REACTION:R04436 +xref: MetaCyc:2.1.1.44-RXN +xref: RHEA:11104 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030746 +name: isoflavone 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone." [EC:2.1.1.46] +synonym: "4'-hydroxyisoflavone methyltransferase activity" EXACT [EC:2.1.1.46] +synonym: "isoflavone methyltransferase activity" EXACT [EC:2.1.1.46] +synonym: "isoflavone O-methyltransferase activity" EXACT [EC:2.1.1.46] +synonym: "S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.46] +xref: EC:2.1.1.46 +xref: MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030747 +name: indolepyruvate C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate." [EC:2.1.1.47] +synonym: "indolepyruvate 3-methyltransferase activity" EXACT [EC:2.1.1.47] +synonym: "indolepyruvate methyltransferase activity" EXACT [EC:2.1.1.47] +synonym: "indolepyruvic acid methyltransferase activity" EXACT [EC:2.1.1.47] +synonym: "S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity" EXACT [EC:2.1.1.47] +synonym: "S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity" EXACT [EC:2.1.1.47] +xref: EC:2.1.1.47 +xref: MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN +xref: RHEA:12112 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030748 +name: amine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine." [EC:2.1.1.49] +synonym: "arylamine N-methyltransferase activity" NARROW [EC:2.1.1.49] +synonym: "nicotine N-methyltransferase activity" NARROW [EC:2.1.1.49] +synonym: "S-adenosyl-L-methionine:amine N-methyltransferase activity" EXACT [EC:2.1.1.49] +synonym: "tryptamine methyltransferase" NARROW [EC:2.1.1.49] +synonym: "tryptamine N-methyltransferase activity" NARROW [EC:2.1.1.49] +xref: EC:2.1.1.49 +xref: MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030749 +name: loganate O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin." [EC:2.1.1.50] +synonym: "loganate methyltransferase activity" EXACT [EC:2.1.1.50] +synonym: "S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity" EXACT [EC:2.1.1.50] +synonym: "S-adenosyl-L-methionine:loganic acid methyltransferase activity" EXACT [EC:2.1.1.50] +xref: EC:2.1.1.50 +xref: MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN +xref: RHEA:12508 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030750 +name: putrescine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.53, RHEA:15037] +synonym: "putrescine methyltransferase activity" EXACT [EC:2.1.1.53] +synonym: "S-adenosyl-L-methionine:putrescine N-methyltransferase activity" EXACT [EC:2.1.1.53] +xref: EC:2.1.1.53 +xref: KEGG_REACTION:R01153 +xref: MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN +xref: RHEA:15037 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030751 +name: licodione 2'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.65, RHEA:18521] +synonym: "S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity" EXACT [EC:2.1.1.65] +xref: EC:2.1.1.65 +xref: KEGG_REACTION:R03623 +xref: MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN +xref: RHEA:18521 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030752 +name: 5-hydroxyfuranocoumarin 5-O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0030764 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin." [EC:2.1.1.69] +synonym: "bergaptol 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "bergaptol methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "bergaptol O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "BMT activity" EXACT [EC:2.1.1.69] +synonym: "furanocoumarin 5-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "furanocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "S-adenosyl-L-methionine:bergaptol O-methyltransferase activity" EXACT [EC:2.1.1.69] +synonym: "S-adenosyl-L-methionine:bergaptolO-methyltransferase activity" EXACT [EC:2.1.1.69] +xref: EC:2.1.1.69 +xref: MetaCyc:2.1.1.69-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030753 +name: 8-hydroxyfuranocoumarin 8-O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0030765 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin." [EC:2.1.1.70] +synonym: "furanocoumarin 8-methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "furanocoumarin 8-O-methyl-transferase activity" EXACT [EC:2.1.1.70] +synonym: "S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "xanthotoxol 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "xanthotoxol methyltransferase activity" EXACT [EC:2.1.1.70] +synonym: "xanthotoxol O-methyltransferase activity" EXACT [] +synonym: "XMT activity" RELATED [EC:2.1.1.70] +xref: EC:2.1.1.70 +xref: KEGG_REACTION:R02982 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030754 +name: apigenin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone." [EC:2.1.1.75] +synonym: "flavonoid methyltransferase activity" EXACT [EC:2.1.1.75] +synonym: "flavonoid O-methyltransferase activity" BROAD [EC:2.1.1.75] +synonym: "S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.75] +xref: EC:2.1.1.75 +xref: MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN +xref: RHEA:20429 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030755 +name: quercetin 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone." [EC:2.1.1.76] +synonym: "flavonoid 3-methyltransferase activity" EXACT [EC:2.1.1.76] +synonym: "flavonol 3-O-methyltransferase activity" RELATED [EC:2.1.1.76] +synonym: "S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity" EXACT [EC:2.1.1.76] +xref: EC:2.1.1.76 +xref: MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN +xref: RHEA:17673 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030756 +name: isoorientin 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin." [EC:2.1.1.78, RHEA:24096] +synonym: "isoorientin 3'-methyltransferase activity" EXACT [EC:2.1.1.78] +synonym: "S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity" EXACT [EC:2.1.1.78] +xref: EC:2.1.1.78 +xref: KEGG_REACTION:R03731 +xref: MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN +xref: RHEA:24096 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030757 +name: 3-methylquercitin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine." [EC:2.1.1.82, RHEA:16181] +synonym: "3-methylquercetin 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] +synonym: "7-OMT activity" RELATED [EC:2.1.1.82] +synonym: "flavonol 7-methyltransferase activity" RELATED [EC:2.1.1.82] +synonym: "flavonol 7-O-methyltransferase activity" RELATED [EC:2.1.1.82] +synonym: "S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] +synonym: "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] +xref: EC:2.1.1.82 +xref: KEGG_REACTION:R05323 +xref: MetaCyc:2.1.1.82-RXN +xref: RHEA:16181 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030758 +name: 3,7-dimethylquercitin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.83, RHEA:21832] +synonym: "3,7-dimethylquercetin 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] +synonym: "4'-OMT activity" RELATED [EC:2.1.1.83] +synonym: "flavonol 4'-methyltransferase activity" RELATED [EC:2.1.1.83] +synonym: "flavonol 4'-O-methyltransferase activity" RELATED [EC:2.1.1.83] +synonym: "S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] +synonym: "S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] +xref: EC:2.1.1.83 +xref: KEGG_REACTION:R03456 +xref: MetaCyc:2.1.1.83-RXN +xref: RHEA:21832 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030759 +name: methylquercetagetin 6-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.84, RHEA:18717] +synonym: "6-OMT" RELATED [EC:2.1.1.84] +synonym: "flavonol 6-methyltransferase activity" EXACT [EC:2.1.1.84] +synonym: "flavonol 6-O-methyltransferase activity" RELATED [EC:2.1.1.84] +synonym: "S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity" EXACT [EC:2.1.1.84] +xref: EC:2.1.1.84 +xref: KEGG_REACTION:R04505 +xref: MetaCyc:2.1.1.84-RXN +xref: RHEA:18717 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030760 +name: pyridine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine." [EC:2.1.1.87, RHEA:16893] +synonym: "pyridine methyltransferase activity" EXACT [EC:2.1.1.87] +synonym: "S-adenosyl-L-methionine:pyridine N-methyltransferase activity" EXACT [EC:2.1.1.87] +xref: EC:2.1.1.87 +xref: KEGG_REACTION:R02862 +xref: MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-175987 "NNMT transfers CH3 from AdoMet to PY" +xref: RHEA:16893 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030761 +name: 8-hydroxyquercitin 8-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.88, RHEA:16593] +synonym: "8-hydroxyquercetin 8-O-methyltransferase activity" EXACT [EC:2.1.1.88] +synonym: "flavonol 8-methyltransferase activity" EXACT [EC:2.1.1.88] +synonym: "flavonol 8-O-methyltransferase activity" RELATED [EC:2.1.1.88] +synonym: "S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity" EXACT [EC:2.1.1.88] +xref: EC:2.1.1.88 +xref: KEGG_REACTION:R04398 +xref: MetaCyc:2.1.1.88-RXN +xref: RHEA:16593 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030762 +name: tetrahydrocolumbamine 2-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine." [EC:2.1.1.89, RHEA:22536] +synonym: "S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity" EXACT [EC:2.1.1.89] +synonym: "tetrahydrocolumbamine methyltransferase activity" EXACT [EC:2.1.1.89] +xref: EC:2.1.1.89 +xref: KEGG_REACTION:R04077 +xref: MetaCyc:2.1.1.89-RXN +xref: RHEA:22536 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030763 +name: isobutyraldoxime O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.91, RHEA:10996] +synonym: "aldoxime methyltransferase activity" EXACT [EC:2.1.1.91] +synonym: "aldoxime O-methyltransferase activity" EXACT [EC:2.1.1.91] +synonym: "S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity" EXACT [EC:2.1.1.91] +synonym: "S-adenosylmethionine:aldoxime O-methyltransferase activity" EXACT [EC:2.1.1.91] +xref: EC:2.1.1.91 +xref: KEGG_REACTION:R04169 +xref: MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN +xref: RHEA:10996 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030766 +name: 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline." [EC:2.1.1.94] +synonym: "11-demethyl-17-deacetylvindoline 11-methyltransferase activity" EXACT [EC:2.1.1.94] +synonym: "S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity" EXACT [EC:2.1.1.94] +synonym: "S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity" EXACT [EC:2.1.1.94] +synonym: "tabersonine 16-O-methyltransferase activity" EXACT [EC:2.1.1.94] +xref: EC:2.1.1.94 +xref: MetaCyc:2.1.1.94-RXN +xref: RHEA:20992 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030767 +name: 3-hydroxyanthranilate 4-C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.97, RHEA:17833] +synonym: "3-hydroxyanthranilate 4-methyltransferase activity" EXACT [EC:2.1.1.97] +synonym: "S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity" EXACT [EC:2.1.1.97] +xref: EC:2.1.1.97 +xref: KEGG_REACTION:R02667 +xref: MetaCyc:2.1.1.97-RXN +xref: RHEA:17833 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030768 +name: 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+)." [EC:2.1.1.99, RHEA:11336] +synonym: "16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity" EXACT [EC:2.1.1.99] +synonym: "3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] +synonym: "NMT activity" EXACT [EC:2.1.1.99] +synonym: "S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] +synonym: "S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] +xref: EC:2.1.1.99 +xref: KEGG_REACTION:R04013 +xref: MetaCyc:2.1.1.99-RXN +xref: RHEA:11336 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030769 +name: macrocin O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin." [EC:2.1.1.101, RHEA:17269] +synonym: "macrocin methyltransferase activity" EXACT [EC:2.1.1.101] +synonym: "S-adenosyl-L-methionine-macrocin O-methyltransferase activity" EXACT [EC:2.1.1.101] +synonym: "S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity" EXACT [EC:2.1.1.101] +xref: EC:2.1.1.101 +xref: KEGG_REACTION:R02858 +xref: MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN +xref: RHEA:17269 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030770 +name: demethylmacrocin O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin." [EC:2.1.1.102, RHEA:17573] +synonym: "demethylmacrocin methyltransferase activity" EXACT [EC:2.1.1.102] +synonym: "S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity" EXACT [EC:2.1.1.102] +xref: EC:2.1.1.102 +xref: KEGG_REACTION:R02859 +xref: MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN +xref: RHEA:17573 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030771 +name: N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.105, RHEA:17405] +synonym: "benzoyl-CoA:anthranilate N-benzoyltransferase" BROAD [EC:2.1.1.105] +synonym: "N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity" EXACT [EC:2.1.1.105] +synonym: "S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity" EXACT [EC:2.1.1.105] +xref: EC:2.1.1.105 +xref: KEGG_REACTION:R04421 +xref: MetaCyc:2.1.1.105-RXN +xref: RHEA:17405 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030772 +name: tryptophan 2-C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+)." [EC:2.1.1.106, RHEA:17321] +synonym: "S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity" EXACT [EC:2.1.1.106] +synonym: "S-adenosylmethionine:tryptophan 2-methyltransferase activity" EXACT [EC:2.1.1.106] +synonym: "tryptophan 2-methyltransferase activity" EXACT [EC:2.1.1.106] +xref: EC:2.1.1.106 +xref: KEGG_REACTION:R08547 +xref: MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN +xref: RHEA:17321 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030773 +name: 6-hydroxymellein O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.108, RHEA:15201] +synonym: "6-hydroxymellein methyltransferase activity" EXACT [EC:2.1.1.108] +synonym: "S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity" EXACT [EC:2.1.1.108] +xref: EC:2.1.1.108 +xref: KEGG_REACTION:R03934 +xref: MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN +xref: RHEA:15201 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030774 +name: anthranilate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.111, RHEA:12180] +synonym: "anthranilic acid N-methyltransferase activity" EXACT [EC:2.1.1.111] +synonym: "S-adenosyl-L-methionine:anthranilate N-methyltransferase activity" EXACT [EC:2.1.1.111] +xref: EC:2.1.1.111 +xref: KEGG_REACTION:R00984 +xref: MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN +xref: RHEA:12180 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030775 +name: glucuronoxylan 4-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate." [EC:2.1.1.112] +synonym: "S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity" EXACT [EC:2.1.1.112] +xref: EC:2.1.1.112 +xref: MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030776 +name: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline." [EC:2.1.1.115] +synonym: "(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] +synonym: "norreticuline N-methyltransferase activity" EXACT [EC:2.1.1.115] +synonym: "S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] +xref: EC:2.1.1.115 +xref: MetaCyc:2.1.1.115-RXN +xref: RHEA:13005 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030777 +name: (S)-scoulerine 9-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.117, RHEA:23808] +synonym: "S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity" EXACT [EC:2.1.1.117] +synonym: "S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity" EXACT [EC:2.1.1.117] +xref: EC:2.1.1.117 +xref: KEGG_REACTION:R03835 +xref: MetaCyc:2.1.1.117-RXN +xref: RHEA:23808 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030778 +name: columbamine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine." [EC:2.1.1.118, RHEA:15373] +synonym: "S-adenosyl-L-methionine:columbamine O-methyltransferase activity" EXACT [EC:2.1.1.118] +xref: EC:2.1.1.118 +xref: KEGG_REACTION:R03721 +xref: MetaCyc:2.1.1.118-RXN +xref: RHEA:15373 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030779 +name: 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+)." [EC:2.1.1.119, RHEA:18541] +synonym: "S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity" EXACT [EC:2.1.1.119] +xref: EC:2.1.1.119 +xref: KEGG_REACTION:R04707 +xref: MetaCyc:2.1.1.119-RXN +xref: RHEA:18541 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030780 +name: 12-hydroxydihydrochelirubine 12-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+)." [EC:2.1.1.120, RHEA:21092] +synonym: "S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity" EXACT [EC:2.1.1.120] +xref: EC:2.1.1.120 +xref: KEGG_REACTION:R04705 +xref: MetaCyc:2.1.1.120-RXN +xref: RHEA:21092 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030781 +name: 6-O-methylnorlaudanosoline 5'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline." [EC:2.1.1.121] +synonym: "S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity" EXACT [EC:2.1.1.121] +xref: EC:2.1.1.121 +xref: MetaCyc:2.1.1.121-RXN +xref: RHEA:11892 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030782 +name: (S)-tetrahydroprotoberberine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine." [EC:2.1.1.122] +synonym: "S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity" EXACT [EC:2.1.1.122] +synonym: "tetrahydroprotoberberine cis-N-methyltransferase activity" EXACT [EC:2.1.1.122] +xref: EC:2.1.1.122 +xref: MetaCyc:2.1.1.122-RXN +xref: RHEA:12805 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030783 +name: [cytochrome c]-methionine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine." [EC:2.1.1.123] +synonym: "cytochrome c-methionine S-methyltransferase activity" EXACT [EC:2.1.1.123] +synonym: "S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity" EXACT [EC:2.1.1.123] +xref: EC:2.1.1.123 +xref: MetaCyc:2.1.1.123-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030784 +name: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline." [EC:2.1.1.116] +synonym: "S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity" EXACT [EC:2.1.1.116] +xref: EC:2.1.1.116 +xref: MetaCyc:2.1.1.116-RXN +xref: RHEA:17789 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030785 +name: [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine." [EC:2.1.1.127] +synonym: "ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity" EXACT [EC:2.1.1.127] +synonym: "ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity" EXACT [EC:2.1.1.127] +synonym: "ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity" EXACT [EC:2.1.1.127] +synonym: "RuBisCO LSMT activity" EXACT [EC:2.1.1.127] +synonym: "RuBisCO methyltransferase activity" EXACT [EC:2.1.1.127] +synonym: "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.127] +synonym: "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.127] +xref: EC:2.1.1.127 +xref: MetaCyc:2.1.1.127-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030786 +name: (RS)-norcoclaurine 6-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine." [EC:2.1.1.128] +synonym: "S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity" EXACT [EC:2.1.1.128] +xref: EC:2.1.1.128 +xref: MetaCyc:2.1.1.128-RXN +xref: RHEA:19941 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030787 +name: inositol 4-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.129, RHEA:23248] +synonym: "myo-inositol 4-O-methyltransferase activity" EXACT [EC:2.1.1.129] +synonym: "myo-inositol 6-O-methyltransferase activity" RELATED [EC:2.1.1.129] +synonym: "S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity" EXACT [EC:2.1.1.129] +synonym: "S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity" EXACT [EC:2.1.1.129] +xref: EC:2.1.1.129 +xref: KEGG_REACTION:R01190 +xref: MetaCyc:2.1.1.129-RXN +xref: RHEA:23248 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030788 +name: precorrin-2 C20-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A." [EC:2.1.1.130, RHEA:16841] +synonym: "S-adenosyl-L-methionine--precorrin-2 methyltransferase activity" EXACT [EC:2.1.1.130] +synonym: "S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity" EXACT [EC:2.1.1.130] +xref: EC:2.1.1.130 +xref: KEGG_REACTION:R03948 +xref: MetaCyc:2.1.1.130-RXN +xref: RHEA:16841 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030789 +name: precorrin-3B C17-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4." [EC:2.1.1.131] +synonym: "CobJ" RELATED [EC:2.1.1.131] +synonym: "precorrin-3 methylase activity" EXACT [EC:2.1.1.131] +synonym: "precorrin-3 methyltransferase activity" EXACT [EC:2.1.1.131] +synonym: "S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity" EXACT [EC:2.1.1.131] +xref: EC:2.1.1.131 +xref: MetaCyc:2.1.1.131-RXN +xref: RHEA:12761 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030790 +name: chlorophenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole." [EC:2.1.1.136] +synonym: "halogenated phenol O-methyltransferase activity" BROAD [EC:2.1.1.136] +synonym: "S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity" EXACT [EC:2.1.1.136] +synonym: "trichlorophenol O-methyltransferase activity" EXACT [EC:2.1.1.136] +xref: EC:2.1.1.136 +xref: MetaCyc:2.1.1.136-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030791 +name: arsenite methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate." [EC:2.1.1.137] +comment: Note that the enzyme arsenite methyltransferase also has methylarsonite methyltransferase activity (GO:0030792). +synonym: "S-adenosyl-L-methionine:arsenic(III) methyltransferase activity" EXACT [EC:2.1.1.137] +synonym: "S-adenosyl-L-methionine:arsenite As-methyltransferase activity" EXACT [EC:2.1.1.137] +synonym: "S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity" EXACT [EC:2.1.1.137] +xref: EC:2.1.1.137 +xref: MetaCyc:2.1.1.137-RXN +xref: Reactome:R-HSA-5696213 "AS3MT transfers CH3 from AdoMet to methylarsonite" +xref: Reactome:R-HSA-5696220 "AS3MT transfers CH3 from AdoMet to arsenite(3-)" +xref: UM-BBD_reactionID:r0805 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030792 +name: methylarsonite methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate." [EC:2.1.1.138] +comment: Note that EC:2.1.1.138 was deleted from EC as the reaction is performed by arsenite methyltransferase (EC:2.1.1.137). +xref: EC:2.1.1 +xref: MetaCyc:2.1.1.138-RXN +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030793 +name: 3'-demethylstaurosporine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine." [EC:2.1.1.139, RHEA:11696] +synonym: "3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity" EXACT [EC:2.1.1.139] +synonym: "S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity" EXACT [EC:2.1.1.139] +synonym: "staurosporine synthase activity" EXACT [EC:2.1.1.139] +xref: EC:2.1.1.139 +xref: KEGG_REACTION:R05757 +xref: MetaCyc:2.1.1.139-RXN +xref: RHEA:11696 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030794 +name: (S)-coclaurine-N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine." [EC:2.1.1.140] +synonym: "S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity" EXACT [EC:2.1.1.140] +xref: EC:2.1.1.140 +xref: MetaCyc:2.1.1.140-RXN +xref: RHEA:17409 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030795 +name: jasmonate O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0045546 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyljasmonate." [EC:2.1.1.141] +synonym: "jasmonic acid carboxyl methyltransferase activity" EXACT [EC:2.1.1.141] +synonym: "S-adenosyl-L-methionine:jasmonate O-methyltransferase activity" EXACT [EC:2.1.1.141] +synonym: "S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity" EXACT [] +xref: EC:2.1.1.141 +xref: MetaCyc:RXN1F-28 +xref: RHEA:13349 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030796 +name: cycloartenol 24-C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.142, RHEA:13137] +synonym: "S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity" EXACT [EC:2.1.1.142] +synonym: "sterol C-methyltransferase activity" BROAD [EC:2.1.1.142] +xref: EC:2.1.1.142 +xref: KEGG_REACTION:R05760 +xref: MetaCyc:2.1.1.142-RXN +xref: RHEA:13137 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030797 +name: 24-methylenesterol C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.143, RHEA:21044] +synonym: "24-methylenelophenol C-24(1)-methyltransferase activity" EXACT [EC:2.1.1.143] +synonym: "24-methylenelophenol C-241-methyltransferase activity" EXACT [EC:2.1.1.143] +synonym: "S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity" EXACT [EC:2.1.1.143] +synonym: "SMT(2) activity" NARROW [EC:2.1.1.143] +synonym: "SMT2" RELATED [EC:2.1.1.143] +xref: EC:2.1.1.143 +xref: KEGG_REACTION:R05776 +xref: MetaCyc:2.1.1.143-RXN +xref: RHEA:21044 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030798 +name: trans-aconitate 2-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine." [EC:2.1.1.144, RHEA:14969] +synonym: "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity" EXACT [EC:2.1.1.144] +xref: EC:2.1.1.144 +xref: KEGG_REACTION:R05763 +xref: MetaCyc:RXN0-2441 +xref: RHEA:14969 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0030799 +name: obsolete regulation of cyclic nucleotide metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of cyclic nucleotide metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030800 +name: obsolete negative regulation of cyclic nucleotide metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "down regulation of cyclic nucleotide metabolic process" EXACT [] +synonym: "down-regulation of cyclic nucleotide metabolic process" EXACT [] +synonym: "downregulation of cyclic nucleotide metabolic process" EXACT [] +synonym: "inhibition of cyclic nucleotide metabolic process" NARROW [] +synonym: "negative regulation of cyclic nucleotide metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030801 +name: obsolete positive regulation of cyclic nucleotide metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cyclic nucleotide metabolic process" NARROW [] +synonym: "positive regulation of cyclic nucleotide metabolism" EXACT [] +synonym: "stimulation of cyclic nucleotide metabolic process" NARROW [] +synonym: "up regulation of cyclic nucleotide metabolic process" EXACT [] +synonym: "up-regulation of cyclic nucleotide metabolic process" EXACT [] +synonym: "upregulation of cyclic nucleotide metabolic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030802 +name: obsolete regulation of cyclic nucleotide biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of cyclic nucleotide anabolism" EXACT [] +synonym: "regulation of cyclic nucleotide biosynthesis" EXACT [] +synonym: "regulation of cyclic nucleotide formation" EXACT [] +synonym: "regulation of cyclic nucleotide synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030803 +name: obsolete negative regulation of cyclic nucleotide biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "down regulation of cyclic nucleotide biosynthetic process" EXACT [] +synonym: "down-regulation of cyclic nucleotide biosynthetic process" EXACT [] +synonym: "downregulation of cyclic nucleotide biosynthetic process" EXACT [] +synonym: "inhibition of cyclic nucleotide biosynthetic process" NARROW [] +synonym: "negative regulation of cyclic nucleotide anabolism" EXACT [] +synonym: "negative regulation of cyclic nucleotide biosynthesis" EXACT [] +synonym: "negative regulation of cyclic nucleotide formation" EXACT [] +synonym: "negative regulation of cyclic nucleotide synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030804 +name: obsolete positive regulation of cyclic nucleotide biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cyclic nucleotide biosynthetic process" NARROW [] +synonym: "positive regulation of cyclic nucleotide anabolism" EXACT [] +synonym: "positive regulation of cyclic nucleotide biosynthesis" EXACT [] +synonym: "positive regulation of cyclic nucleotide formation" EXACT [] +synonym: "positive regulation of cyclic nucleotide synthesis" EXACT [] +synonym: "stimulation of cyclic nucleotide biosynthetic process" NARROW [] +synonym: "up regulation of cyclic nucleotide biosynthetic process" EXACT [] +synonym: "up-regulation of cyclic nucleotide biosynthetic process" EXACT [] +synonym: "upregulation of cyclic nucleotide biosynthetic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030805 +name: regulation of cyclic nucleotide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] +synonym: "regulation of cyclic nucleotide breakdown" EXACT [] +synonym: "regulation of cyclic nucleotide catabolism" EXACT [] +synonym: "regulation of cyclic nucleotide degradation" EXACT [] +is_a: GO:0030811 ! regulation of nucleotide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009214 ! cyclic nucleotide catabolic process +relationship: regulates GO:0009214 ! cyclic nucleotide catabolic process + +[Term] +id: GO:0030806 +name: obsolete negative regulation of cyclic nucleotide catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "down regulation of cyclic nucleotide catabolic process" EXACT [] +synonym: "down-regulation of cyclic nucleotide catabolic process" EXACT [] +synonym: "downregulation of cyclic nucleotide catabolic process" EXACT [] +synonym: "inhibition of cyclic nucleotide catabolic process" NARROW [] +synonym: "negative regulation of cyclic nucleotide breakdown" EXACT [] +synonym: "negative regulation of cyclic nucleotide catabolism" EXACT [] +synonym: "negative regulation of cyclic nucleotide degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030807 +name: obsolete positive regulation of cyclic nucleotide catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cyclic nucleotide catabolic process" NARROW [] +synonym: "positive regulation of cyclic nucleotide breakdown" EXACT [] +synonym: "positive regulation of cyclic nucleotide catabolism" EXACT [] +synonym: "positive regulation of cyclic nucleotide degradation" EXACT [] +synonym: "stimulation of cyclic nucleotide catabolic process" NARROW [] +synonym: "up regulation of cyclic nucleotide catabolic process" EXACT [] +synonym: "up-regulation of cyclic nucleotide catabolic process" EXACT [] +synonym: "upregulation of cyclic nucleotide catabolic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030808 +name: regulation of nucleotide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] +synonym: "regulation of nucleotide anabolism" EXACT [] +synonym: "regulation of nucleotide biosynthesis" EXACT [] +synonym: "regulation of nucleotide formation" EXACT [] +synonym: "regulation of nucleotide synthesis" EXACT [] +is_a: GO:0006140 ! regulation of nucleotide metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009165 ! nucleotide biosynthetic process +relationship: regulates GO:0009165 ! nucleotide biosynthetic process + +[Term] +id: GO:0030809 +name: negative regulation of nucleotide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] +synonym: "down regulation of nucleotide biosynthetic process" EXACT [] +synonym: "down-regulation of nucleotide biosynthetic process" EXACT [] +synonym: "downregulation of nucleotide biosynthetic process" EXACT [] +synonym: "inhibition of nucleotide biosynthetic process" NARROW [] +synonym: "negative regulation of nucleotide anabolism" EXACT [] +synonym: "negative regulation of nucleotide biosynthesis" EXACT [] +synonym: "negative regulation of nucleotide formation" EXACT [] +synonym: "negative regulation of nucleotide synthesis" EXACT [] +is_a: GO:0030808 ! regulation of nucleotide biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045980 ! negative regulation of nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009165 ! nucleotide biosynthetic process +relationship: negatively_regulates GO:0009165 ! nucleotide biosynthetic process + +[Term] +id: GO:0030810 +name: positive regulation of nucleotide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] +synonym: "activation of nucleotide biosynthetic process" NARROW [] +synonym: "positive regulation of nucleotide anabolism" EXACT [] +synonym: "positive regulation of nucleotide biosynthesis" EXACT [] +synonym: "positive regulation of nucleotide formation" EXACT [] +synonym: "positive regulation of nucleotide synthesis" EXACT [] +synonym: "stimulation of nucleotide biosynthetic process" NARROW [] +synonym: "up regulation of nucleotide biosynthetic process" EXACT [] +synonym: "up-regulation of nucleotide biosynthetic process" EXACT [] +synonym: "upregulation of nucleotide biosynthetic process" EXACT [] +is_a: GO:0030808 ! regulation of nucleotide biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045981 ! positive regulation of nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009165 ! nucleotide biosynthetic process +relationship: positively_regulates GO:0009165 ! nucleotide biosynthetic process + +[Term] +id: GO:0030811 +name: regulation of nucleotide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] +synonym: "regulation of nucleotide breakdown" EXACT [] +synonym: "regulation of nucleotide catabolism" EXACT [] +synonym: "regulation of nucleotide degradation" EXACT [] +is_a: GO:0006140 ! regulation of nucleotide metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009166 ! nucleotide catabolic process +relationship: regulates GO:0009166 ! nucleotide catabolic process + +[Term] +id: GO:0030812 +name: negative regulation of nucleotide catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] +synonym: "down regulation of nucleotide catabolic process" EXACT [] +synonym: "down-regulation of nucleotide catabolic process" EXACT [] +synonym: "downregulation of nucleotide catabolic process" EXACT [] +synonym: "inhibition of nucleotide catabolic process" NARROW [] +synonym: "negative regulation of nucleotide breakdown" EXACT [] +synonym: "negative regulation of nucleotide catabolism" EXACT [] +synonym: "negative regulation of nucleotide degradation" EXACT [] +is_a: GO:0030811 ! regulation of nucleotide catabolic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045980 ! negative regulation of nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009166 ! nucleotide catabolic process +relationship: negatively_regulates GO:0009166 ! nucleotide catabolic process + +[Term] +id: GO:0030813 +name: positive regulation of nucleotide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] +synonym: "activation of nucleotide catabolic process" NARROW [] +synonym: "positive regulation of nucleotide breakdown" EXACT [] +synonym: "positive regulation of nucleotide catabolism" EXACT [] +synonym: "positive regulation of nucleotide degradation" EXACT [] +synonym: "stimulation of nucleotide catabolic process" NARROW [] +synonym: "up regulation of nucleotide catabolic process" EXACT [] +synonym: "up-regulation of nucleotide catabolic process" EXACT [] +synonym: "upregulation of nucleotide catabolic process" EXACT [] +is_a: GO:0030811 ! regulation of nucleotide catabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045981 ! positive regulation of nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009166 ! nucleotide catabolic process +relationship: positively_regulates GO:0009166 ! nucleotide catabolic process + +[Term] +id: GO:0030814 +name: obsolete regulation of cAMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of 3',5' cAMP metabolic process" EXACT [] +synonym: "regulation of 3',5' cAMP metabolism" EXACT [] +synonym: "regulation of 3',5'-cAMP metabolic process" EXACT [] +synonym: "regulation of 3',5'-cAMP metabolism" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] +synonym: "regulation of cAMP metabolism" EXACT [] +synonym: "regulation of cyclic AMP metabolic process" EXACT [] +synonym: "regulation of cyclic AMP metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030815 +name: obsolete negative regulation of cAMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "down regulation of cAMP metabolic process" EXACT [] +synonym: "down-regulation of cAMP metabolic process" EXACT [] +synonym: "downregulation of cAMP metabolic process" EXACT [] +synonym: "inhibition of cAMP metabolic process" NARROW [] +synonym: "negative regulation of 3',5' cAMP metabolic process" EXACT [] +synonym: "negative regulation of 3',5' cAMP metabolism" EXACT [] +synonym: "negative regulation of 3',5'-cAMP metabolic process" EXACT [] +synonym: "negative regulation of 3',5'-cAMP metabolism" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] +synonym: "negative regulation of cAMP metabolism" EXACT [] +synonym: "negative regulation of cyclic AMP metabolic process" EXACT [] +synonym: "negative regulation of cyclic AMP metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030816 +name: obsolete positive regulation of cAMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cAMP metabolic process" NARROW [] +synonym: "positive regulation of 3',5' cAMP metabolic process" EXACT [] +synonym: "positive regulation of 3',5' cAMP metabolism" EXACT [] +synonym: "positive regulation of 3',5'-cAMP metabolic process" EXACT [] +synonym: "positive regulation of 3',5'-cAMP metabolism" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] +synonym: "positive regulation of cAMP metabolism" EXACT [] +synonym: "positive regulation of cyclic AMP metabolic process" EXACT [] +synonym: "positive regulation of cyclic AMP metabolism" EXACT [] +synonym: "stimulation of cAMP metabolic process" NARROW [] +synonym: "up regulation of cAMP metabolic process" EXACT [] +synonym: "up-regulation of cAMP metabolic process" EXACT [] +synonym: "upregulation of cAMP metabolic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030817 +name: obsolete regulation of cAMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: This term was obsoleted because it represents a molecular function. +synonym: "regulation of 3',5' cAMP biosynthesis" EXACT [] +synonym: "regulation of 3',5' cAMP biosynthetic process" EXACT [] +synonym: "regulation of 3',5'-cAMP biosynthesis" EXACT [] +synonym: "regulation of 3',5'-cAMP biosynthetic process" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] +synonym: "regulation of cAMP anabolism" EXACT [] +synonym: "regulation of cAMP biosynthesis" EXACT [] +synonym: "regulation of cAMP formation" EXACT [] +synonym: "regulation of cAMP synthesis" EXACT [] +synonym: "regulation of cyclic AMP biosynthesis" EXACT [] +synonym: "regulation of cyclic AMP biosynthetic process" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14718 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0030818 +name: obsolete negative regulation of cAMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that the term represents a molecular function. +synonym: "down regulation of cAMP biosynthetic process" EXACT [] +synonym: "down-regulation of cAMP biosynthetic process" EXACT [] +synonym: "downregulation of cAMP biosynthetic process" EXACT [] +synonym: "inhibition of cAMP biosynthetic process" NARROW [] +synonym: "negative regulation of 3',5' cAMP biosynthesis" EXACT [] +synonym: "negative regulation of 3',5' cAMP biosynthetic process" EXACT [] +synonym: "negative regulation of 3',5'-cAMP biosynthesis" EXACT [] +synonym: "negative regulation of 3',5'-cAMP biosynthetic process" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] +synonym: "negative regulation of cAMP anabolism" EXACT [] +synonym: "negative regulation of cAMP biosynthesis" EXACT [] +synonym: "negative regulation of cAMP formation" EXACT [] +synonym: "negative regulation of cAMP synthesis" EXACT [] +synonym: "negative regulation of cyclic AMP biosynthesis" EXACT [] +synonym: "negative regulation of cyclic AMP biosynthetic process" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14718 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0030819 +name: obsolete positive regulation of cAMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +synonym: "activation of cAMP biosynthetic process" NARROW [] +synonym: "positive regulation of 3',5' cAMP biosynthesis" EXACT [] +synonym: "positive regulation of 3',5' cAMP biosynthetic process" EXACT [] +synonym: "positive regulation of 3',5'-cAMP biosynthesis" EXACT [] +synonym: "positive regulation of 3',5'-cAMP biosynthetic process" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] +synonym: "positive regulation of cAMP anabolism" EXACT [] +synonym: "positive regulation of cAMP biosynthesis" EXACT [] +synonym: "positive regulation of cAMP formation" EXACT [] +synonym: "positive regulation of cAMP synthesis" EXACT [] +synonym: "positive regulation of cyclic AMP biosynthesis" EXACT [] +synonym: "positive regulation of cyclic AMP biosynthetic process" EXACT [] +synonym: "stimulation of cAMP biosynthetic process" NARROW [] +synonym: "up regulation of cAMP biosynthetic process" EXACT [] +synonym: "up-regulation of cAMP biosynthetic process" EXACT [] +synonym: "upregulation of cAMP biosynthetic process" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14718 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0030820 +name: obsolete regulation of cAMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of 3',5' cAMP catabolic process" EXACT [] +synonym: "regulation of 3',5' cAMP catabolism" EXACT [] +synonym: "regulation of 3',5'-cAMP catabolic process" EXACT [] +synonym: "regulation of 3',5'-cAMP catabolism" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] +synonym: "regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] +synonym: "regulation of cAMP breakdown" EXACT [] +synonym: "regulation of cAMP catabolism" EXACT [] +synonym: "regulation of cAMP degradation" EXACT [] +synonym: "regulation of cyclic AMP catabolic process" EXACT [] +synonym: "regulation of cyclic AMP catabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030821 +name: obsolete negative regulation of cAMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "down regulation of cAMP catabolic process" EXACT [] +synonym: "down-regulation of cAMP catabolic process" EXACT [] +synonym: "downregulation of cAMP catabolic process" EXACT [] +synonym: "inhibition of cAMP catabolic process" NARROW [] +synonym: "negative regulation of 3',5' cAMP catabolic process" EXACT [] +synonym: "negative regulation of 3',5' cAMP catabolism" EXACT [] +synonym: "negative regulation of 3',5'-cAMP catabolic process" EXACT [] +synonym: "negative regulation of 3',5'-cAMP catabolism" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] +synonym: "negative regulation of cAMP breakdown" EXACT [] +synonym: "negative regulation of cAMP catabolism" EXACT [] +synonym: "negative regulation of cAMP degradation" EXACT [] +synonym: "negative regulation of cyclic AMP catabolic process" EXACT [] +synonym: "negative regulation of cyclic AMP catabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030822 +name: obsolete positive regulation of cAMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cAMP catabolic process" NARROW [] +synonym: "positive regulation of 3',5' cAMP catabolic process" EXACT [] +synonym: "positive regulation of 3',5' cAMP catabolism" EXACT [] +synonym: "positive regulation of 3',5'-cAMP catabolic process" EXACT [] +synonym: "positive regulation of 3',5'-cAMP catabolism" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] +synonym: "positive regulation of cAMP breakdown" EXACT [] +synonym: "positive regulation of cAMP catabolism" EXACT [] +synonym: "positive regulation of cAMP degradation" EXACT [] +synonym: "positive regulation of cyclic AMP catabolic process" EXACT [] +synonym: "positive regulation of cyclic AMP catabolism" EXACT [] +synonym: "stimulation of cAMP catabolic process" NARROW [] +synonym: "up regulation of cAMP catabolic process" EXACT [] +synonym: "up-regulation of cAMP catabolic process" EXACT [] +synonym: "upregulation of cAMP catabolic process" EXACT [] +is_obsolete: true +consider: GO:0071878 + +[Term] +id: GO:0030823 +name: obsolete regulation of cGMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of cGMP metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030824 +name: obsolete negative regulation of cGMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] +comment: The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism. +synonym: "down regulation of cGMP metabolic process" EXACT [] +synonym: "down-regulation of cGMP metabolic process" EXACT [] +synonym: "downregulation of cGMP metabolic process" EXACT [] +synonym: "inhibition of cGMP metabolic process" NARROW [] +synonym: "negative regulation of cGMP metabolism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030825 +name: obsolete positive regulation of cGMP metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cGMP metabolic process" NARROW [] +synonym: "positive regulation of cGMP metabolism" EXACT [] +synonym: "stimulation of cGMP metabolic process" NARROW [] +synonym: "up regulation of cGMP metabolic process" EXACT [] +synonym: "up-regulation of cGMP metabolic process" EXACT [] +synonym: "upregulation of cGMP metabolic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030826 +name: obsolete regulation of cGMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of cGMP anabolism" EXACT [] +synonym: "regulation of cGMP biosynthesis" EXACT [] +synonym: "regulation of cGMP formation" EXACT [] +synonym: "regulation of cGMP synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030827 +name: obsolete negative regulation of cGMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] +comment: The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism. +synonym: "down regulation of cGMP biosynthetic process" EXACT [] +synonym: "down-regulation of cGMP biosynthetic process" EXACT [] +synonym: "downregulation of cGMP biosynthetic process" EXACT [] +synonym: "inhibition of cGMP biosynthetic process" NARROW [] +synonym: "negative regulation of cGMP anabolism" EXACT [] +synonym: "negative regulation of cGMP biosynthesis" EXACT [] +synonym: "negative regulation of cGMP formation" EXACT [] +synonym: "negative regulation of cGMP synthesis" EXACT [] +is_obsolete: true +consider: GO:0030251 + +[Term] +id: GO:0030828 +name: obsolete positive regulation of cGMP biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represent the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cGMP biosynthetic process" NARROW [] +synonym: "positive regulation of cGMP anabolism" EXACT [] +synonym: "positive regulation of cGMP biosynthesis" EXACT [] +synonym: "positive regulation of cGMP formation" EXACT [] +synonym: "positive regulation of cGMP synthesis" EXACT [] +synonym: "stimulation of cGMP biosynthetic process" NARROW [] +synonym: "up regulation of cGMP biosynthetic process" EXACT [] +synonym: "up-regulation of cGMP biosynthetic process" EXACT [] +synonym: "upregulation of cGMP biosynthetic process" EXACT [] +is_obsolete: true +consider: GO:0004383 + +[Term] +id: GO:0030829 +name: obsolete regulation of cGMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represent the regulation of a signaling pathway, not regulation of metabolism. +synonym: "regulation of cGMP breakdown" EXACT [] +synonym: "regulation of cGMP catabolism" EXACT [] +synonym: "regulation of cGMP degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030830 +name: obsolete negative regulation of cGMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] +comment: The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism. +synonym: "down regulation of cGMP catabolic process" EXACT [] +synonym: "down-regulation of cGMP catabolic process" EXACT [] +synonym: "downregulation of cGMP catabolic process" EXACT [] +synonym: "inhibition of cGMP catabolic process" NARROW [] +synonym: "negative regulation of cGMP breakdown" EXACT [] +synonym: "negative regulation of cGMP catabolism" EXACT [] +synonym: "negative regulation of cGMP degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030831 +name: obsolete positive regulation of cGMP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] +comment: The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism. +synonym: "activation of cGMP catabolic process" NARROW [] +synonym: "positive regulation of cGMP breakdown" EXACT [] +synonym: "positive regulation of cGMP catabolism" EXACT [] +synonym: "positive regulation of cGMP degradation" EXACT [] +synonym: "stimulation of cGMP catabolic process" NARROW [] +synonym: "up regulation of cGMP catabolic process" EXACT [] +synonym: "up-regulation of cGMP catabolic process" EXACT [] +synonym: "upregulation of cGMP catabolic process" EXACT [] +is_obsolete: true + +[Term] +id: GO:0030832 +name: regulation of actin filament length +namespace: biological_process +def: "Any process that controls the length of actin filaments in a cell." [GOC:dph, GOC:mah] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +is_a: GO:0032535 ! regulation of cellular component size +is_a: GO:0032956 ! regulation of actin cytoskeleton organization + +[Term] +id: GO:0030833 +name: regulation of actin filament polymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament." [GOC:mah] +synonym: "regulation of actin polymerization" EXACT [] +is_a: GO:0008064 ! regulation of actin polymerization or depolymerization +is_a: GO:0032271 ! regulation of protein polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030041 ! actin filament polymerization +relationship: regulates GO:0030041 ! actin filament polymerization + +[Term] +id: GO:0030834 +name: regulation of actin filament depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament." [GOC:mah] +synonym: "regulation of actin depolymerization" EXACT [] +is_a: GO:0008064 ! regulation of actin polymerization or depolymerization +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030042 ! actin filament depolymerization +relationship: regulates GO:0030042 ! actin filament depolymerization + +[Term] +id: GO:0030835 +name: negative regulation of actin filament depolymerization +namespace: biological_process +alt_id: GO:0030044 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization." [GOC:mah] +comment: Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin polymerization ; GO:0030837'). +synonym: "actin filament stabilization" EXACT [] +synonym: "down regulation of actin filament depolymerization" EXACT [] +synonym: "down-regulation of actin filament depolymerization" EXACT [] +synonym: "downregulation of actin filament depolymerization" EXACT [] +synonym: "inhibition of actin filament depolymerization" NARROW [] +synonym: "negative regulation of actin depolymerization" EXACT [] +synonym: "negative regulation of actin polymerization and/or depolymerization" BROAD [] +is_a: GO:0030834 ! regulation of actin filament depolymerization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1901880 ! negative regulation of protein depolymerization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030042 ! actin filament depolymerization +relationship: negatively_regulates GO:0030042 ! actin filament depolymerization + +[Term] +id: GO:0030836 +name: positive regulation of actin filament depolymerization +namespace: biological_process +alt_id: GO:0030045 +def: "Any process that activates or increases the frequency, rate or extent of actin depolymerization." [GOC:mah] +comment: Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838'). +synonym: "actin filament destabilization" EXACT [] +synonym: "activation of actin filament depolymerization" NARROW [] +synonym: "positive regulation of actin depolymerization" EXACT [] +synonym: "positive regulation of actin polymerization and/or depolymerization" BROAD [] +synonym: "stimulation of actin filament depolymerization" NARROW [] +synonym: "up regulation of actin filament depolymerization" EXACT [] +synonym: "up-regulation of actin filament depolymerization" EXACT [] +synonym: "upregulation of actin filament depolymerization" EXACT [] +is_a: GO:0030834 ! regulation of actin filament depolymerization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1901881 ! positive regulation of protein depolymerization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030042 ! actin filament depolymerization +relationship: positively_regulates GO:0030042 ! actin filament depolymerization + +[Term] +id: GO:0030837 +name: negative regulation of actin filament polymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization." [GOC:mah] +comment: Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin depolymerization ; GO:0030835'). +synonym: "down regulation of actin filament polymerization" EXACT [] +synonym: "down-regulation of actin filament polymerization" EXACT [] +synonym: "downregulation of actin filament polymerization" EXACT [] +synonym: "inhibition of actin filament polymerization" NARROW [] +synonym: "negative regulation of actin polymerization" EXACT [] +synonym: "negative regulation of actin polymerization and/or depolymerization" BROAD [] +is_a: GO:0030833 ! regulation of actin filament polymerization +is_a: GO:0032272 ! negative regulation of protein polymerization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030041 ! actin filament polymerization +relationship: negatively_regulates GO:0030041 ! actin filament polymerization + +[Term] +id: GO:0030838 +name: positive regulation of actin filament polymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin polymerization." [GOC:mah] +comment: Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836'). +synonym: "activation of actin filament polymerization" NARROW [] +synonym: "positive regulation of actin polymerization" EXACT [] +synonym: "positive regulation of actin polymerization and/or depolymerization" BROAD [] +synonym: "stimulation of actin filament polymerization" NARROW [] +synonym: "up regulation of actin filament polymerization" EXACT [] +synonym: "up-regulation of actin filament polymerization" EXACT [] +synonym: "upregulation of actin filament polymerization" EXACT [] +is_a: GO:0030833 ! regulation of actin filament polymerization +is_a: GO:0032273 ! positive regulation of protein polymerization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030041 ! actin filament polymerization +relationship: positively_regulates GO:0030041 ! actin filament polymerization + +[Term] +id: GO:0030839 +name: regulation of intermediate filament polymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament." [GOC:mah] +is_a: GO:0032271 ! regulation of protein polymerization +is_a: GO:0045108 ! regulation of intermediate filament polymerization or depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045107 ! intermediate filament polymerization +relationship: regulates GO:0045107 ! intermediate filament polymerization + +[Term] +id: GO:0030840 +name: negative regulation of intermediate filament polymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization." [GOC:mah] +comment: Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament depolymerization ; GO:0030843'). +synonym: "down regulation of intermediate filament polymerization" EXACT [] +synonym: "down-regulation of intermediate filament polymerization" EXACT [] +synonym: "downregulation of intermediate filament polymerization" EXACT [] +synonym: "inhibition of intermediate filament polymerization" NARROW [] +synonym: "negative regulation of intermediate filament polymerization and/or depolymerization" BROAD [] +is_a: GO:0030839 ! regulation of intermediate filament polymerization +is_a: GO:0032272 ! negative regulation of protein polymerization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045107 ! intermediate filament polymerization +relationship: negatively_regulates GO:0045107 ! intermediate filament polymerization + +[Term] +id: GO:0030841 +name: positive regulation of intermediate filament polymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization." [GOC:mah] +comment: Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament depolymerization ; GO:0030844'). +synonym: "activation of intermediate filament polymerization" NARROW [] +synonym: "positive regulation of intermediate filament polymerization and/or depolymerization" BROAD [] +synonym: "stimulation of intermediate filament polymerization" NARROW [] +synonym: "up regulation of intermediate filament polymerization" EXACT [] +synonym: "up-regulation of intermediate filament polymerization" EXACT [] +synonym: "upregulation of intermediate filament polymerization" EXACT [] +is_a: GO:0030839 ! regulation of intermediate filament polymerization +is_a: GO:0032273 ! positive regulation of protein polymerization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045107 ! intermediate filament polymerization +relationship: positively_regulates GO:0045107 ! intermediate filament polymerization + +[Term] +id: GO:0030842 +name: regulation of intermediate filament depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament." [GOC:mah] +is_a: GO:0045108 ! regulation of intermediate filament polymerization or depolymerization +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045106 ! intermediate filament depolymerization +relationship: regulates GO:0045106 ! intermediate filament depolymerization + +[Term] +id: GO:0030843 +name: negative regulation of intermediate filament depolymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization." [GOC:mah] +comment: Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament polymerization ; GO:0030840'). +synonym: "down regulation of intermediate filament depolymerization" EXACT [] +synonym: "down-regulation of intermediate filament depolymerization" EXACT [] +synonym: "downregulation of intermediate filament depolymerization" EXACT [] +synonym: "inhibition of intermediate filament depolymerization" NARROW [] +synonym: "negative regulation of intermediate filament polymerization and/or depolymerization" BROAD [] +is_a: GO:0030842 ! regulation of intermediate filament depolymerization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1901880 ! negative regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045106 ! intermediate filament depolymerization +relationship: negatively_regulates GO:0045106 ! intermediate filament depolymerization + +[Term] +id: GO:0030844 +name: positive regulation of intermediate filament depolymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization." [GOC:mah] +comment: Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament polymerization ; GO:0030841'). +synonym: "activation of intermediate filament depolymerization" NARROW [] +synonym: "positive regulation of intermediate filament polymerization and/or depolymerization" BROAD [] +synonym: "stimulation of intermediate filament depolymerization" NARROW [] +synonym: "up regulation of intermediate filament depolymerization" EXACT [] +synonym: "up-regulation of intermediate filament depolymerization" EXACT [] +synonym: "upregulation of intermediate filament depolymerization" EXACT [] +is_a: GO:0030842 ! regulation of intermediate filament depolymerization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1901881 ! positive regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045106 ! intermediate filament depolymerization +relationship: positively_regulates GO:0045106 ! intermediate filament depolymerization + +[Term] +id: GO:0030845 +name: phospholipase C-inhibiting G protein-coupled receptor signaling pathway +namespace: biological_process +def: "A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, PMID:8280098] +comment: This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) inhibition. +synonym: "G-protein-coupled inhibitory pathway of phospholipase C" EXACT [PMID:8280098] +synonym: "GPCR signaling pathway coupled to inhibition of phospholipase C activity" EXACT [GOC:signaling] +synonym: "GPCR signaling pathway via inhibition of PLC" EXACT [GOC:signaling] +synonym: "inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway" NARROW [GOC:mah] +synonym: "phospholipase C inhibition" RELATED [GOC:dph, GOC:tb] +synonym: "phospholipase C-inhibiting G-protein coupled receptor signaling pathway" EXACT [] +synonym: "PLC-inhibiting GPCR signaling pathway" EXACT [GOC:signaling] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: has_part GO:1900275 ! negative regulation of phospholipase C activity + +[Term] +id: GO:0030846 +name: termination of RNA polymerase II transcription, poly(A)-coupled +namespace: biological_process +def: "The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination." [GOC:txnOH, PMID:12944462, PMID:18679429] +synonym: "termination of RNA polymerase II transcription, polyadenylation-coupled" RELATED [] +synonym: "transcription termination from Pol II promoter, poly(A) coupled" RELATED [] +synonym: "transcription termination from Pol II promoter, RNA polymerase(A) coupled" RELATED [] +is_a: GO:0006369 ! termination of RNA polymerase II transcription + +[Term] +id: GO:0030847 +name: termination of RNA polymerase II transcription, exosome-dependent +namespace: biological_process +def: "The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end." [GOC:txnOH, PMID:12944462, PMID:18679429] +synonym: "termination of RNA polymerase II transcription, poly(A)-independent" EXACT [] +synonym: "transcription termination from Pol II promoter, poly(A)-independent" EXACT [] +synonym: "transcription termination from Pol II promoter, RNA polymerase(A)-independent" EXACT [] +is_a: GO:0006369 ! termination of RNA polymerase II transcription + +[Term] +id: GO:0030848 +name: threo-3-hydroxyaspartate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate." [EC:4.3.1.16, RHEA:12424] +synonym: "3-hydroxyaspartate dehydratase activity" BROAD [GOC:mcc, PMID:10481099] +synonym: "L-threo-3-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.16] +synonym: "threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)" EXACT [EC:4.3.1.16] +synonym: "threo-3-hydroxy-L-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.16] +synonym: "threo-3-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.16] +xref: EC:4.3.1.16 +xref: KEGG_REACTION:R05758 +xref: MetaCyc:4.3.1.16-RXN +xref: RHEA:12424 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0030849 +name: autosome +namespace: cellular_component +def: "Any chromosome other than a sex chromosome." [GOC:mah] +comment: Note that this term is mainly relevant in organisms that have both sex chromosomes and non-sex-determining chromosomes in an individual organism. +xref: Wikipedia:Autosome +is_a: GO:0005694 ! chromosome + +[Term] +id: GO:0030850 +name: prostate gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." [PMID:11839751] +synonym: "prostate development" EXACT [] +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0048732 ! gland development +relationship: part_of GO:0001655 ! urogenital system development + +[Term] +id: GO:0030851 +name: granulocyte differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils." [GOC:ecd, http://life.nthu.edu.tw/~g864204/dict-search1.htm] +synonym: "granulocyte cell differentiation" EXACT [] +is_a: GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0030852 +name: regulation of granulocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of granulocyte differentiation." [GOC:mah] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030851 ! granulocyte differentiation +relationship: regulates GO:0030851 ! granulocyte differentiation + +[Term] +id: GO:0030853 +name: negative regulation of granulocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation." [GOC:mah] +synonym: "down regulation of granulocyte differentiation" EXACT [] +synonym: "down-regulation of granulocyte differentiation" EXACT [] +synonym: "downregulation of granulocyte differentiation" EXACT [] +synonym: "inhibition of granulocyte differentiation" NARROW [] +is_a: GO:0002762 ! negative regulation of myeloid leukocyte differentiation +is_a: GO:0030852 ! regulation of granulocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030851 ! granulocyte differentiation +relationship: negatively_regulates GO:0030851 ! granulocyte differentiation + +[Term] +id: GO:0030854 +name: positive regulation of granulocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of granulocyte differentiation." [GOC:mah] +synonym: "activation of granulocyte differentiation" NARROW [] +synonym: "stimulation of granulocyte differentiation" NARROW [] +synonym: "up regulation of granulocyte differentiation" EXACT [] +synonym: "up-regulation of granulocyte differentiation" EXACT [] +synonym: "upregulation of granulocyte differentiation" EXACT [] +is_a: GO:0002763 ! positive regulation of myeloid leukocyte differentiation +is_a: GO:0030852 ! regulation of granulocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030851 ! granulocyte differentiation +relationship: positively_regulates GO:0030851 ! granulocyte differentiation + +[Term] +id: GO:0030855 +name: epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0060429 ! epithelium development + +[Term] +id: GO:0030856 +name: regulation of epithelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030855 ! epithelial cell differentiation +relationship: regulates GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0030857 +name: negative regulation of epithelial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] +synonym: "down regulation of epithelial cell differentiation" EXACT [] +synonym: "down-regulation of epithelial cell differentiation" EXACT [] +synonym: "downregulation of epithelial cell differentiation" EXACT [] +synonym: "inhibition of epithelial cell differentiation" NARROW [] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0045596 ! negative regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030855 ! epithelial cell differentiation +relationship: negatively_regulates GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0030858 +name: positive regulation of epithelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] +synonym: "activation of epithelial cell differentiation" NARROW [] +synonym: "stimulation of epithelial cell differentiation" NARROW [] +synonym: "up regulation of epithelial cell differentiation" EXACT [] +synonym: "up-regulation of epithelial cell differentiation" EXACT [] +synonym: "upregulation of epithelial cell differentiation" EXACT [] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0045597 ! positive regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030855 ! epithelial cell differentiation +relationship: positively_regulates GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0030859 +name: polarized epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis." [GOC:mah] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0001738 ! morphogenesis of a polarized epithelium + +[Term] +id: GO:0030860 +name: regulation of polarized epithelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation." [GOC:mah] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030859 ! polarized epithelial cell differentiation +relationship: regulates GO:0030859 ! polarized epithelial cell differentiation + +[Term] +id: GO:0030861 +name: negative regulation of polarized epithelial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation." [GOC:mah] +synonym: "down regulation of polarized epithelial cell differentiation" EXACT [] +synonym: "down-regulation of polarized epithelial cell differentiation" EXACT [] +synonym: "downregulation of polarized epithelial cell differentiation" EXACT [] +synonym: "inhibition of polarized epithelial cell differentiation" NARROW [] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0030860 ! regulation of polarized epithelial cell differentiation +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030859 ! polarized epithelial cell differentiation +relationship: negatively_regulates GO:0030859 ! polarized epithelial cell differentiation + +[Term] +id: GO:0030862 +name: positive regulation of polarized epithelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of polarized epithelial cell differentiation." [GOC:mah] +synonym: "activation of polarized epithelial cell differentiation" NARROW [] +synonym: "stimulation of polarized epithelial cell differentiation" NARROW [] +synonym: "up regulation of polarized epithelial cell differentiation" EXACT [] +synonym: "up-regulation of polarized epithelial cell differentiation" EXACT [] +synonym: "upregulation of polarized epithelial cell differentiation" EXACT [] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0030860 ! regulation of polarized epithelial cell differentiation +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030859 ! polarized epithelial cell differentiation +relationship: positively_regulates GO:0030859 ! polarized epithelial cell differentiation + +[Term] +id: GO:0030863 +name: cortical cytoskeleton +namespace: cellular_component +def: "The portion of the cytoskeleton that lies just beneath the plasma membrane." [GOC:mah] +is_a: GO:0005856 ! cytoskeleton +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0030864 +name: cortical actin cytoskeleton +namespace: cellular_component +def: "The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane." [GOC:mah] +is_a: GO:0030863 ! cortical cytoskeleton +intersection_of: GO:0030863 ! cortical cytoskeleton +intersection_of: part_of GO:0015629 ! actin cytoskeleton +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0030865 +name: cortical cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] +synonym: "cortical cytoskeleton organisation" EXACT [] +synonym: "cortical cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0030866 +name: cortical actin cytoskeleton organization +namespace: biological_process +alt_id: GO:0033109 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane." [GOC:dph, GOC:jl, GOC:mah, GOC:pf] +synonym: "actin cortex stabilization" EXACT [] +synonym: "cortical actin cytoskeleton organisation" EXACT [] +synonym: "cortical actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] +synonym: "cortical actin cytoskeleton stabilization" EXACT [] +synonym: "cortical resistance" RELATED [] +is_a: GO:0030036 ! actin cytoskeleton organization +is_a: GO:0030865 ! cortical cytoskeleton organization + +[Term] +id: GO:0030867 +name: rough endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the rough endoplasmic reticulum." [GOC:mah] +synonym: "RER membrane" EXACT [NIF_Subcellular:sao3089754107] +synonym: "rough ER membrane" EXACT [] +xref: NIF_Subcellular:sao3089754107 +is_a: GO:0005789 ! endoplasmic reticulum membrane +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005791 ! rough endoplasmic reticulum + +[Term] +id: GO:0030868 +name: smooth endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the smooth endoplasmic reticulum." [GOC:mah] +synonym: "SER membrane" EXACT [] +synonym: "smooth ER membrane" EXACT [] +xref: NIF_Subcellular:sao1596955044 +is_a: GO:0005789 ! endoplasmic reticulum membrane +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005790 ! smooth endoplasmic reticulum + +[Term] +id: GO:0030869 +name: RENT complex +namespace: cellular_component +def: "A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit." [PMID:12196389] +is_a: GO:0005677 ! chromatin silencing complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0030870 +name: Mre11 complex +namespace: cellular_component +def: "Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins." [GOC:mah, GOC:vw, PMID:11988766, PMID:17674145] +synonym: "MRN complex" EXACT [] +synonym: "MRX complex" EXACT [] +synonym: "Rad50 complex" EXACT [] +synonym: "RAD50-MRE11-NBN complex" EXACT [CORUM:2767] +synonym: "Rad50-Rad32-Nbs1 complex" EXACT [] +synonym: "RMX complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0030874 +name: nucleolar chromatin +namespace: cellular_component +def: "The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000790 ! nuclear chromatin +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0030875 +name: rDNA protrusion +namespace: cellular_component +def: "Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining." [PMID:1629244] +comment: Note that this component is characterized in Schizosaccharomyces, particularly with respect to the DAPI staining pattern. +synonym: "ribosomal DNA protrusion" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030874 ! nucleolar chromatin + +[Term] +id: GO:0030876 +name: interleukin-20 receptor complex +namespace: cellular_component +def: "A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits." [PMID:12351624] +synonym: "IL-20 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0030877 +name: beta-catenin destruction complex +namespace: cellular_component +alt_id: GO:0034742 +alt_id: GO:0034747 +def: "A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome." [PMID:14600025] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +synonym: "23S APC complex" NARROW [] +synonym: "APC-Axin-1-beta-catenin complex" EXACT [] +synonym: "Axin-APC-beta-catenin-GSK3B complex" EXACT [] +synonym: "BDC" EXACT [GOC:bf, GOC:PARL, PMID:22899650] +synonym: "beta-catenin degradation complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0030878 +name: thyroid gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone." [GOC:dgh] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0030879 +name: mammary gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages." [PMID:9576833] +synonym: "mammogenesis" NARROW [GOC:dph] +is_a: GO:0048732 ! gland development + +[Term] +id: GO:0030880 +name: RNA polymerase complex +namespace: cellular_component +def: "Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits." [GOC:mah] +subset: goslim_pir +synonym: "multisubunit RNA polymerase" EXACT [] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030881 +name: beta-2-microglobulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with beta-2-microglobulin." [GOC:mah] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030882 +name: lipid antigen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipid antigen." [PMID:14500461] +is_a: GO:0003823 ! antigen binding +is_a: GO:0008289 ! lipid binding + +[Term] +id: GO:0030883 +name: endogenous lipid antigen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endogenous cellular lipid antigen." [PMID:14500461] +is_a: GO:0030882 ! lipid antigen binding + +[Term] +id: GO:0030884 +name: exogenous lipid antigen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an exogenous lipid antigen (examples include microbial lipids and glycolipids)." [PMID:14500461] +is_a: GO:0030882 ! lipid antigen binding + +[Term] +id: GO:0030885 +name: regulation of myeloid dendritic cell activation +namespace: biological_process +def: "Any process that modulates the frequency or rate of myeloid dendritic cell activation." [GOC:mah] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001773 ! myeloid dendritic cell activation +relationship: regulates GO:0001773 ! myeloid dendritic cell activation + +[Term] +id: GO:0030886 +name: negative regulation of myeloid dendritic cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation." [GOC:mah] +synonym: "down regulation of myeloid dendritic cell activation" EXACT [] +synonym: "down-regulation of myeloid dendritic cell activation" EXACT [] +synonym: "downregulation of myeloid dendritic cell activation" EXACT [] +synonym: "inhibition of myeloid dendritic cell activation" NARROW [] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:0030885 ! regulation of myeloid dendritic cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001773 ! myeloid dendritic cell activation +relationship: negatively_regulates GO:0001773 ! myeloid dendritic cell activation + +[Term] +id: GO:0030887 +name: positive regulation of myeloid dendritic cell activation +namespace: biological_process +def: "Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation." [GOC:mah] +synonym: "activation of myeloid dendritic cell activation" NARROW [] +synonym: "stimulation of myeloid dendritic cell activation" NARROW [] +synonym: "up regulation of myeloid dendritic cell activation" EXACT [] +synonym: "up-regulation of myeloid dendritic cell activation" EXACT [] +synonym: "upregulation of myeloid dendritic cell activation" EXACT [] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:0030885 ! regulation of myeloid dendritic cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001773 ! myeloid dendritic cell activation +relationship: positively_regulates GO:0001773 ! myeloid dendritic cell activation + +[Term] +id: GO:0030888 +name: regulation of B cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of B cell proliferation." [GOC:mah] +synonym: "regulation of B lymphocyte proliferation" EXACT [] +synonym: "regulation of B-cell proliferation" EXACT [] +synonym: "regulation of B-lymphocyte proliferation" EXACT [] +is_a: GO:0050670 ! regulation of lymphocyte proliferation +is_a: GO:0050864 ! regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042100 ! B cell proliferation +relationship: regulates GO:0042100 ! B cell proliferation + +[Term] +id: GO:0030889 +name: negative regulation of B cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of B cell proliferation." [GOC:mah] +synonym: "down regulation of B cell proliferation" EXACT [] +synonym: "down-regulation of B cell proliferation" EXACT [] +synonym: "downregulation of B cell proliferation" EXACT [] +synonym: "inhibition of B cell proliferation" NARROW [] +synonym: "negative regulation of B lymphocyte proliferation" EXACT [] +synonym: "negative regulation of B-cell proliferation" EXACT [] +synonym: "negative regulation of B-lymphocyte proliferation" EXACT [] +is_a: GO:0030888 ! regulation of B cell proliferation +is_a: GO:0050672 ! negative regulation of lymphocyte proliferation +is_a: GO:0050869 ! negative regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042100 ! B cell proliferation +relationship: negatively_regulates GO:0042100 ! B cell proliferation + +[Term] +id: GO:0030890 +name: positive regulation of B cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of B cell proliferation." [GOC:mah] +synonym: "activation of B cell proliferation" NARROW [] +synonym: "positive regulation of B lymphocyte proliferation" EXACT [] +synonym: "positive regulation of B-cell proliferation" EXACT [] +synonym: "positive regulation of B-lymphocyte proliferation" EXACT [] +synonym: "stimulation of B cell proliferation" NARROW [] +synonym: "up regulation of B cell proliferation" EXACT [] +synonym: "up-regulation of B cell proliferation" EXACT [] +synonym: "upregulation of B cell proliferation" EXACT [] +is_a: GO:0030888 ! regulation of B cell proliferation +is_a: GO:0050671 ! positive regulation of lymphocyte proliferation +is_a: GO:0050871 ! positive regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042100 ! B cell proliferation +relationship: positively_regulates GO:0042100 ! B cell proliferation + +[Term] +id: GO:0030891 +name: VCB complex +namespace: cellular_component +def: "A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1." [GOC:mah, PMID:11865071] +synonym: "pVHL-elongin C-elongin B complex" EXACT [] +synonym: "VHL complex" EXACT [] +synonym: "von Hippel-Lindau tumor suppressor complex" EXACT [] +is_a: GO:0000153 ! cytoplasmic ubiquitin ligase complex + +[Term] +id: GO:0030892 +name: mitotic cohesin complex +namespace: cellular_component +def: "A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex." [GOC:mah, PMID:12750522] +is_a: GO:0008278 ! cohesin complex + +[Term] +id: GO:0030893 +name: meiotic cohesin complex +namespace: cellular_component +def: "A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex." [GOC:mah, PMID:12750522] +is_a: GO:0008278 ! cohesin complex + +[Term] +id: GO:0030894 +name: replisome +namespace: cellular_component +def: "A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins." [GOC:mah, GOC:vw] +subset: goslim_pir +synonym: "DNA synthesome complex" RELATED [CORUM:1001] +synonym: "RC complex" RELATED [CORUM:309, PMID:12006500] +synonym: "replication-competent complex" RELATED [CORUM:309, PMID:12006500] +xref: Wikipedia:Replisome +is_a: GO:0032993 ! protein-DNA complex +relationship: has_part GO:0033202 ! DNA helicase complex +relationship: has_part GO:0042575 ! DNA polymerase complex +relationship: part_of GO:0005657 ! replication fork + +[Term] +id: GO:0030895 +name: apolipoprotein B mRNA editing enzyme complex +namespace: cellular_component +def: "Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP)." [PMID:10781591] +synonym: "apoB mRNA editing enzyme complex" EXACT [] +synonym: "APOBEC" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0030896 +name: checkpoint clamp complex +namespace: cellular_component +def: "Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage." [PMID:12531008] +comment: Note that the following subunit names have been used: human RAD9/RAD1/HUS1; S. pombe Rad9/Rad1/Hus1; S. cerevisiae Ddc1p/Rad17p/Mec3p. +synonym: "CCC" EXACT [] +synonym: "Rad9-Hus1-Rad1 (9-1-1) clamp complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0030897 +name: HOPS complex +namespace: cellular_component +def: "A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion." [PMID:10944212, PMID:23645161] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:0099023 ! vesicle tethering complex + +[Term] +id: GO:0030898 +name: actin-dependent ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate." [GOC:mah] +synonym: "actin-activated ATPase activity" EXACT [] +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0030899 +name: calcium-dependent ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+)." [GOC:mah] +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0030900 +name: forebrain development +namespace: biological_process +def: "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain] +synonym: "prosencephalon development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0030901 +name: midbrain development +namespace: biological_process +def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain] +synonym: "mesencephalon development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0030902 +name: hindbrain development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain] +synonym: "rhombencephalon development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0030903 +name: notochord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh] +is_a: GO:0048568 ! embryonic organ development + +[Term] +id: GO:0030904 +name: retromer complex +namespace: cellular_component +def: "A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35." [GOC:bf, PMID:26220253, PMID:27385586, PMID:9700157] +subset: goslim_pir +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0030905 +name: retromer, tubulation complex +namespace: cellular_component +def: "The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6." [GOC:bf, PMID:26220253, PMID:9700157] +synonym: "heterodimeric membrane-deforming retromer subcomplex" EXACT [GOC:bf, GOC:PARL, PMID:22193161] +synonym: "retromer complex, outer shell" EXACT [] +synonym: "SNX-BAR dimer" EXACT [PMID:26220253] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030904 ! retromer complex + +[Term] +id: GO:0030906 +name: retromer, cargo-selective complex +namespace: cellular_component +def: "The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals." [GOC:bf, PMID:11102511, PMID:26220253, PMID:9700157] +synonym: "cargo-selective retromer subcomplex" EXACT [PMID:19531583, PMID:20923837] +synonym: "retromer complex, inner shell" EXACT [] +synonym: "retromer CSC" EXACT [GOC:bf, GOC:PARL] +synonym: "retromer, cargo recognition complex" EXACT [PMID:26220253] +synonym: "retromer, CRC" EXACT [GOC:bf, GOC:PARL, PMID:26220253] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030904 ! retromer complex + +[Term] +id: GO:0030907 +name: MBF transcription complex +namespace: cellular_component +def: "A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p." [GOC:mah, PMID:11206552, PMID:15838511, PMID:18160399, PMID:9343385] +synonym: "DSC1 transcription factor complex" EXACT [] +synonym: "MBF" EXACT [] +synonym: "Mlu1-box binding factor" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0030908 +name: protein splicing +namespace: biological_process +def: "The post-translational removal of peptide sequences from within a protein sequence." [GOC:mah] +xref: Wikipedia:Protein_splicing +is_a: GO:0016485 ! protein processing + +[Term] +id: GO:0030909 +name: non-intein-mediated protein splicing +namespace: biological_process +def: "The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins." [GOC:mah] +is_a: GO:0030908 ! protein splicing + +[Term] +id: GO:0030910 +name: olfactory placode formation +namespace: biological_process +def: "The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:dgh] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0043584 ! nose development +relationship: part_of GO:0071699 ! olfactory placode morphogenesis + +[Term] +id: GO:0030911 +name: TPR domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices." [GOC:mah] +synonym: "tetratricopeptide repeat domain binding" EXACT [GOC:sl] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0030912 +name: response to deep water +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle." [GOC:mah] +comment: Note that this term should not be confused with 'response to flooding ; GO:0009413'; which refers to immersion in water on a shorter time scale. +is_a: GO:0009415 ! response to water + +[Term] +id: GO:0030913 +name: paranodal junction assembly +namespace: biological_process +def: "Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier." [PMID:14715942] +synonym: "paranodal axoglial junction formation" EXACT [PMID:18803321] +synonym: "paranodal junction biosynthesis" EXACT [] +synonym: "paranodal junction formation" EXACT [] +is_a: GO:0007043 ! cell-cell junction assembly +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +relationship: part_of GO:0032288 ! myelin assembly + +[Term] +id: GO:0030914 +name: STAGA complex +namespace: cellular_component +def: "A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex; for example, the human complex contains the transcription-transformation cofactor TRRAP, hGCN5L acetylase, novel human ADA-like and SPT-like cofactors, and a subset of TAFs." [PMID:11564863] +comment: See also the cellular component term 'SAGA complex ; GO:0000124'. +synonym: "SPT3-TAF9-GCN5 acetylase complex" EXACT [GOC:rl, PMID:18838386] +synonym: "STAGA coactivator complex" EXACT [] +is_a: GO:0070461 ! SAGA-type complex + +[Term] +id: GO:0030915 +name: Smc5-Smc6 complex +namespace: cellular_component +def: "A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans." [GOC:rb, PMID:14701739, PMID:15738391, PMID:27373152] +is_a: GO:0106068 ! SUMO ligase complex +relationship: part_of GO:0000793 ! condensed chromosome + +[Term] +id: GO:0030916 +name: otic vesicle formation +namespace: biological_process +def: "The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:dgh] +synonym: "otocyst biosynthesis" EXACT [] +synonym: "otocyst formation" EXACT [] +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0071600 ! otic vesicle morphogenesis + +[Term] +id: GO:0030917 +name: midbrain-hindbrain boundary development +namespace: biological_process +def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh] +synonym: "isthmic organizer development" EXACT [] +synonym: "isthmomesencephalic boundary development" EXACT [] +synonym: "isthmus development" EXACT [] +synonym: "MHB development" EXACT [] +synonym: "midbrain-hindbrain orgainizer development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development +relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning + +[Term] +id: GO:0030919 +name: peptidyl-serine O-acetylation +namespace: biological_process +def: "The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine." [PMID:489587, PMID:7309355, RESID:AA0364] +xref: RESID:AA0364 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0030920 ! peptidyl-serine acetylation + +[Term] +id: GO:0030920 +name: peptidyl-serine acetylation +namespace: biological_process +def: "The acetylation of peptidyl-serine." [GOC:mah] +is_a: GO:0006473 ! protein acetylation + +[Term] +id: GO:0030921 +name: peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine +namespace: biological_process +def: "The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues." [PMID:9631087, RESID:AA0183] +xref: RESID:AA0183 +is_a: GO:0018251 ! peptidyl-tyrosine dehydrogenation + +[Term] +id: GO:0030922 +name: peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine +namespace: biological_process +def: "The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues." [PMID:12623015, RESID:AA0365] +xref: RESID:AA0365 +is_a: GO:0018251 ! peptidyl-tyrosine dehydrogenation + +[Term] +id: GO:0030923 +name: metal incorporation into metallo-oxygen cluster +namespace: biological_process +def: "The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate." [GOC:jsg] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0030924 +name: manganese incorporation into metallo-oxygen cluster +namespace: biological_process +def: "The incorporation of manganese into a metallo-oxygen cluster." [GOC:jsg] +is_a: GO:0030923 ! metal incorporation into metallo-oxygen cluster + +[Term] +id: GO:0030925 +name: calcium incorporation into metallo-oxygen cluster +namespace: biological_process +def: "The incorporation of calcium into a metallo-oxygen cluster." [GOC:jsg] +is_a: GO:0030923 ! metal incorporation into metallo-oxygen cluster + +[Term] +id: GO:0030926 +name: calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide +namespace: biological_process +def: "The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site." [PMID:14764885, RESID:AA0366] +xref: RESID:AA0366 +is_a: GO:0030925 ! calcium incorporation into metallo-oxygen cluster + +[Term] +id: GO:0030927 +name: manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide +namespace: biological_process +def: "The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site." [PMID:14764885, RESID:AA0366] +xref: RESID:AA0366 +is_a: GO:0030924 ! manganese incorporation into metallo-oxygen cluster + +[Term] +id: GO:0030929 +name: ADPG pyrophosphorylase complex +namespace: cellular_component +def: "Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits." [GOC:tb, PMID:9680965] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0030930 +name: homotetrameric ADPG pyrophosphorylase complex +namespace: cellular_component +def: "A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0030929 ! ADPG pyrophosphorylase complex + +[Term] +id: GO:0030931 +name: heterotetrameric ADPG pyrophosphorylase complex +namespace: cellular_component +def: "A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0030929 ! ADPG pyrophosphorylase complex + +[Term] +id: GO:0030932 +name: amyloplast ADPG pyrophosphorylase complex +namespace: cellular_component +def: "An ADPG pyrophosphorylase complex found in the amyloplast." [GOC:mah] +is_a: GO:0031009 ! plastid ADPG pyrophosphorylase complex +intersection_of: GO:0030929 ! ADPG pyrophosphorylase complex +intersection_of: part_of GO:0009501 ! amyloplast +relationship: part_of GO:0009501 ! amyloplast + +[Term] +id: GO:0030933 +name: chloroplast ADPG pyrophosphorylase complex +namespace: cellular_component +def: "An ADPG pyrophosphorylase complex found in the chloroplast." [GOC:mah] +is_a: GO:0031009 ! plastid ADPG pyrophosphorylase complex +intersection_of: GO:0030929 ! ADPG pyrophosphorylase complex +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0030934 +name: anchoring collagen complex +namespace: cellular_component +def: "Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures." [ISBN:0721639976] +synonym: "connecting collagen" EXACT [ISBN:0721639976] +synonym: "linking collagen" EXACT [ISBN:0721639976] +is_a: GO:0005581 ! collagen trimer +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0030935 +name: sheet-forming collagen trimer +namespace: cellular_component +def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet." [PMID:7188361] +synonym: "hexagonal network-forming collagen" EXACT [ISBN:0815316194] +is_a: GO:0098642 ! network-forming collagen trimer +intersection_of: GO:0005581 ! collagen trimer +intersection_of: part_of GO:0098646 ! collagen sheet +relationship: part_of GO:0098646 ! collagen sheet + +[Term] +id: GO:0030936 +name: transmembrane collagen trimer +namespace: cellular_component +def: "Any collagen trimer that passes through a lipid bilayer membrane." [ISBN:0721639976] +synonym: "MACIT" EXACT [ISBN:0198599587] +is_a: GO:0005581 ! collagen trimer +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0005581 ! collagen trimer +intersection_of: part_of GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0030937 +name: collagen type XVII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin." [ISBN:0721639976, PMID:19693541, PMID:21421911] +is_a: GO:0030936 ! transmembrane collagen trimer +is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion +is_a: GO:0098733 ! hemidesmosome associated protein complex + +[Term] +id: GO:0030938 +name: collagen type XVIII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XVIII) chains." [ISBN:0721639976, PMID:21421911] +is_a: GO:0098651 ! basement membrane collagen trimer + +[Term] +id: GO:0030939 +name: obsolete response to long-day photoperiod +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark." [GOC:pj] +comment: This term was made obsolete because it was wrongly defined. +synonym: "response to long-day photoperiod" EXACT [] +is_obsolete: true +consider: GO:0048571 + +[Term] +id: GO:0030940 +name: obsolete response to short-day photoperiod +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light." [GOC:pj] +comment: This term was made obsolete because it was wrongly defined. +synonym: "response to short-day photoperiod" EXACT [] +is_obsolete: true +consider: GO:0048572 + +[Term] +id: GO:0030941 +name: chloroplast targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast." [GOC:mah] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0030942 +name: endoplasmic reticulum signal peptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum." [GOC:mah] +synonym: "ER signal peptide binding" EXACT [] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0030943 +name: mitochondrion targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion." [GOC:mah] +synonym: "mitochondrial targeting sequence binding" EXACT [] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0030944 +name: DDEL sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [GOC:mah] +is_a: GO:0046923 ! ER retention sequence binding + +[Term] +id: GO:0030945 +name: protein tyrosine phosphatase activity, via thiol-phosphate intermediate +namespace: molecular_function +def: "The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate." [GOC:hjd] +is_a: GO:0004725 ! protein tyrosine phosphatase activity + +[Term] +id: GO:0030946 +name: protein tyrosine phosphatase activity, metal-dependent +namespace: molecular_function +def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions." [GOC:mah] +is_a: GO:0004725 ! protein tyrosine phosphatase activity + +[Term] +id: GO:0030947 +name: regulation of vascular endothelial growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] +synonym: "regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] +synonym: "regulation of VEGF receptor signaling pathway" EXACT [] +synonym: "regulation of VEGF receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +relationship: regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway + +[Term] +id: GO:0030948 +name: negative regulation of vascular endothelial growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] +synonym: "down regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +synonym: "downregulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +synonym: "inhibition of vascular endothelial growth factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] +synonym: "negative regulation of VEGF receptor signaling pathway" EXACT [] +synonym: "negative regulation of VEGF receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0030947 ! regulation of vascular endothelial growth factor receptor signaling pathway +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +relationship: negatively_regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway + +[Term] +id: GO:0030949 +name: positive regulation of vascular endothelial growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] +synonym: "activation of vascular endothelial growth factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] +synonym: "positive regulation of VEGF receptor signaling pathway" EXACT [] +synonym: "positive regulation of VEGF receptor signalling pathway" EXACT [] +synonym: "stimulation of vascular endothelial growth factor receptor signaling pathway" NARROW [] +synonym: "up regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +synonym: "upregulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0030947 ! regulation of vascular endothelial growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +relationship: positively_regulates GO:0048010 ! vascular endothelial growth factor receptor signaling pathway + +[Term] +id: GO:0030950 +name: establishment or maintenance of actin cytoskeleton polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures." [GOC:mah] +is_a: GO:0030036 ! actin cytoskeleton organization +is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity + +[Term] +id: GO:0030951 +name: establishment or maintenance of microtubule cytoskeleton polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity + +[Term] +id: GO:0030952 +name: establishment or maintenance of cytoskeleton polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah] +synonym: "cytoskeleton polarization" RELATED [] +is_a: GO:0007010 ! cytoskeleton organization +is_a: GO:0007163 ! establishment or maintenance of cell polarity + +[Term] +id: GO:0030953 +name: astral microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles." [GOC:mah] +synonym: "astral microtubule organisation" EXACT [] +synonym: "astral microtubule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007051 ! spindle organization +is_a: GO:0031122 ! cytoplasmic microtubule organization + +[Term] +id: GO:0030954 +name: astral microtubule nucleation +namespace: biological_process +def: "The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule." [GOC:mah] +is_a: GO:0030953 ! astral microtubule organization +is_a: GO:0051418 ! microtubule nucleation by microtubule organizing center + +[Term] +id: GO:0030955 +name: potassium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with potassium (K+) ions." [GOC:mah] +is_a: GO:0031420 ! alkali metal ion binding + +[Term] +id: GO:0030956 +name: glutamyl-tRNA(Gln) amidotransferase complex +namespace: cellular_component +def: "A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms." [GOC:mlg] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567'. +synonym: "AdT" RELATED [GOC:rb] +synonym: "GatCAB" NARROW [GOC:rb] +synonym: "GatFAB" NARROW [GOC:rb] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0030957 +name: Tat protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus." [GOC:mah, PMID:9094689] +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding + +[Term] +id: GO:0030958 +name: RITS complex +namespace: cellular_component +def: "A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing." [PMID:14704433] +is_a: GO:0031332 ! RNAi effector complex +relationship: part_of GO:0005720 ! nuclear heterochromatin + +[Term] +id: GO:0030959 +name: peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine +namespace: biological_process +def: "The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link." [RESID:AA0367] +xref: RESID:AA0367 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0030960 +name: peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine +namespace: biological_process +def: "The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link." [PDB:1NGK, PMID:12719529, RESID:AA0368] +xref: RESID:AA0368 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0030961 +name: peptidyl-arginine hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine." [GOC:mah] +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0030962 +name: peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine +namespace: biological_process +def: "The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine." [PMID:10978343, RESID:AA0369] +xref: RESID:AA0369 +is_a: GO:0030961 ! peptidyl-arginine hydroxylation + +[Term] +id: GO:0030963 +name: peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine +namespace: biological_process +def: "The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine." [PMID:10978343, RESID:AA0370] +xref: RESID:AA0370 +is_a: GO:0017185 ! peptidyl-lysine hydroxylation + +[Term] +id: GO:0030964 +name: NADH dehydrogenase complex +namespace: cellular_component +alt_id: GO:0030025 +alt_id: GO:0030966 +alt_id: GO:0031675 +alt_id: GO:0031677 +alt_id: GO:0031678 +alt_id: GO:0045280 +def: "An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone." [GOC:mah] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (quinone) activity ; GO:0050136'. +subset: goslim_pir +synonym: "Complex I" EXACT [] +synonym: "NADH dehydrogenase complex (plastoquinone)" NARROW [] +synonym: "NADH dehydrogenase complex (quinone)" NARROW [] +synonym: "NADH dehydrogenase complex (ubiquinone)" NARROW [] +synonym: "NADH:plastoquinone reductase complex" NARROW [] +synonym: "plastid NADH dehydrogenase complex (plastoquinone)" NARROW [] +xref: Wikipedia:NADH_dehydrogenase +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030965 +name: plasma membrane electron transport, NADH to quinone +namespace: biological_process +def: "The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase." [GOC:mah, GOC:sd] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0042774 ! plasma membrane ATP synthesis coupled electron transport + +[Term] +id: GO:0030968 +name: endoplasmic reticulum unfolded protein response +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation." [GOC:mah, PMID:12042763] +comment: Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'. +synonym: "ER unfolded protein response" EXACT [] +synonym: "erUPR" EXACT [] +synonym: "SREBP-mediated signalling pathway" RELATED [] +is_a: GO:0007165 ! signal transduction +is_a: GO:0034976 ! response to endoplasmic reticulum stress +relationship: part_of GO:0034620 ! cellular response to unfolded protein + +[Term] +id: GO:0030969 +name: obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes." [GOC:mah, PMID:12042763, PMID:21924241] +comment: The reason for obsoletion is that this process represent a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498). +synonym: "HAC1 mRNA splicing" NARROW [PMID:21924241] +synonym: "IRE1-mediated XBP-1 mRNA splicing" NARROW [GOC:bf] +synonym: "Ire1p-mediated HAC-1 mRNA splicing" NARROW [GOC:bf] +synonym: "non-spliceosomal mRNA splicing in the unfolded protein response pathway" EXACT [PMID:10357823] +synonym: "spliceosome-independent UFP-specific transcription factor mRNA processing" EXACT [GOC:dph] +synonym: "UFP-specific transcription factor mRNA processing during unfolded protein response" RELATED [GOC:dph, GOC:tb] +synonym: "UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response" EXACT [GOC:bf] +synonym: "UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum UPR" EXACT [GOC:bf] +synonym: "UFP-specific transcription factor mRNA processing involved in ER unfolded protein response" EXACT [GOC:bf] +synonym: "UFP-specific transcription factor mRNA processing involved in ER UPR" EXACT [GOC:bf] +synonym: "unconventional mRNA splicing involved in UPR" EXACT [GOC:bf] +synonym: "unconventional splicing of XBP1 mRNA" EXACT [PMID:11779464, PMID:26068456] +synonym: "unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor" RELATED [] +synonym: "unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase" RELATED [] +synonym: "XBP1 mRNA splicing" EXACT [PMID:11779464, PMID:25968568] +synonym: "XBP1 mRNA splicing under conditions of endoplasmic reticulum (ER) stress" NARROW [PMID:21924241] +synonym: "XBP1 mRNA splicing, via endonucleolytic cleavage and ligation" EXACT [GOC:bf] +is_obsolete: true +consider: GO:0036498 + +[Term] +id: GO:0030970 +name: retrograde protein transport, ER to cytosol +namespace: biological_process +def: "The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon." [PMID:11994744] +synonym: "protein dislocation from ER" EXACT [GOC:dph, GOC:krc] +synonym: "protein retrotranslocation, ER to cytosol" EXACT [GOC:bf] +synonym: "retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [] +is_a: GO:0032527 ! protein exit from endoplasmic reticulum +is_a: GO:1903513 ! endoplasmic reticulum to cytosol transport +relationship: part_of GO:0036503 ! ERAD pathway + +[Term] +id: GO:0030971 +name: receptor tyrosine kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity." [GOC:mah] +synonym: "transmembrane receptor protein tyrosine kinase ligand binding" RELATED [] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:1990782 ! protein tyrosine kinase binding + +[Term] +id: GO:0030972 +name: obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis +namespace: biological_process +def: "OBSOLETE. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0815332181] +comment: This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'. +synonym: "apoptotic cleavage of cytosolic proteins" EXACT [] +synonym: "cleavage of cytosolic proteins involved in apoptosis" BROAD [] +synonym: "cleavage of cytosolic proteins involved in execution phase of apoptosis" EXACT [] +is_obsolete: true +consider: GO:0097200 + +[Term] +id: GO:0030973 +name: molybdate ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with molybdate (MoO4 2-) ions." [GOC:mlg] +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0030974 +name: thiamine pyrophosphate transmembrane transport +namespace: biological_process +def: "The process in which thiamine pyrophosphate is transported across a membrane." [GOC:mlg] +synonym: "thiamin diphosphate transport" EXACT [] +synonym: "thiamin pyrophosphate transport" EXACT [] +synonym: "thiamine diphosphate transport" EXACT [] +synonym: "thiamine pyrophosphate transport" NARROW [] +synonym: "TPP transport" EXACT [] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072348 ! sulfur compound transport +is_a: GO:0072531 ! pyrimidine-containing compound transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0030975 +name: thiamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:mlg] +synonym: "thiamin binding" EXACT [] +synonym: "vitamin B1 binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0030976 +name: thiamine pyrophosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases." [GOC:mlg] +synonym: "aneurine pyrophosphate binding" EXACT [] +synonym: "cocarboxylase binding" EXACT [] +synonym: "diphosphothiamin binding" EXACT [] +synonym: "thiamin pyrophosphate binding" EXACT [] +synonym: "TPP binding" EXACT [] +is_a: GO:0019842 ! vitamin binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043169 ! cation binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0030977 +name: taurine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with taurine." [GOC:mlg] +is_a: GO:0043210 ! alkanesulfonate binding + +[Term] +id: GO:0030978 +name: alpha-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds." [GOC:mah] +synonym: "alpha-glucan metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process + +[Term] +id: GO:0030979 +name: alpha-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds." [GOC:mah] +synonym: "alpha-glucan anabolism" EXACT [] +synonym: "alpha-glucan biosynthesis" EXACT [] +synonym: "alpha-glucan formation" EXACT [] +synonym: "alpha-glucan synthesis" EXACT [] +is_a: GO:0009250 ! glucan biosynthetic process +is_a: GO:0030978 ! alpha-glucan metabolic process + +[Term] +id: GO:0030980 +name: alpha-glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alpha-glucans." [GOC:mah] +synonym: "alpha-glucan breakdown" EXACT [] +synonym: "alpha-glucan catabolism" EXACT [] +synonym: "alpha-glucan degradation" EXACT [] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0030978 ! alpha-glucan metabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process + +[Term] +id: GO:0030981 +name: cortical microtubule cytoskeleton +namespace: cellular_component +def: "The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane." [GOC:mah] +is_a: GO:0030863 ! cortical cytoskeleton +relationship: part_of GO:0015630 ! microtubule cytoskeleton + +[Term] +id: GO:0030982 +name: adventurous gliding motility +namespace: biological_process +def: "A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime." [GOC:mlg, PMID:11967173] +synonym: "adventurous gliding movement" EXACT [] +is_a: GO:0071976 ! cell gliding + +[Term] +id: GO:0030983 +name: mismatched DNA binding +namespace: molecular_function +alt_id: GO:0032134 +def: "Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches." [GOC:mah] +synonym: "mispair binding" EXACT [] +synonym: "mispaired DNA binding" EXACT [] +is_a: GO:0003690 ! double-stranded DNA binding + +[Term] +id: GO:0030984 +name: kininogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors." [GOC:mah, PMID:9520414] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0030985 +name: high molecular weight kininogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kininogen of high molecular mass." [GOC:mah, PMID:9520414] +synonym: "HK binding" EXACT [] +synonym: "HMW kininogen binding" EXACT [] +is_a: GO:0030984 ! kininogen binding + +[Term] +id: GO:0030986 +name: low molecular weight kininogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kininogen of low molecular mass." [GOC:mah, PMID:9520414] +synonym: "LK binding" EXACT [] +synonym: "LMW kininogen binding" EXACT [] +is_a: GO:0030984 ! kininogen binding + +[Term] +id: GO:0030987 +name: high molecular weight kininogen receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a high molecular weight kininogen receptor." [GOC:mah] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0030988 +name: high molecular weight kininogen receptor complex +namespace: cellular_component +def: "A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins." [GOC:mah, PMID:11290596] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0030989 +name: dynein-driven meiotic oscillatory nuclear movement +namespace: biological_process +def: "Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein." [GOC:vw, PMID:16111942, PMID:9572142] +comment: Dynein-driven meiotic oscillatory nuclear movement precedes meiotic recombination. +synonym: "HNM" EXACT [] +synonym: "horsetail movement" EXACT [] +synonym: "horsetail nuclear movement" EXACT [GOC:vw] +is_a: GO:0030473 ! nuclear migration along microtubule +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0030990 +name: intraciliary transport particle +namespace: cellular_component +def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166] +comment: Note that we deem cilia and microtubule-based flagella to be equivalent. +subset: goslim_pir +synonym: "IFT complex" RELATED [] +synonym: "intraflagellar transport complex" EXACT [] +synonym: "intraflagellar transport particle" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0030991 +name: intraciliary transport particle A +namespace: cellular_component +def: "The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa." [GOC:cilia, GOC:kmv, PMID:14570576] +comment: Note that we deem cilia and microtubule-based flagella to be equivalent. +synonym: "IFT A complex" RELATED [] +synonym: "IFT complex A" RELATED [] +synonym: "intraflagellar transport complex A" EXACT [] +synonym: "intraflagellar transport particle A" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030990 ! intraciliary transport particle + +[Term] +id: GO:0030992 +name: intraciliary transport particle B +namespace: cellular_component +def: "The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:19253336] +comment: Note that we deem cilia and microtubule-based flagella to be equivalent. +synonym: "IFT B complex" RELATED [] +synonym: "IFT complex B" RELATED [] +synonym: "intraflagellar transport complex B" EXACT [] +synonym: "intraflagellar transport particle B" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030990 ! intraciliary transport particle + +[Term] +id: GO:0030993 +name: axonemal heterotrimeric kinesin-II complex +namespace: cellular_component +def: "A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme." [GOC:kmv, PMID:14570576] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005930 ! axoneme + +[Term] +id: GO:0030994 +name: primary cell septum disassembly +namespace: biological_process +def: "Dissolution of the primary septum during cell separation." [PMID:12665550] +synonym: "hydrolysis of primary cell septum" EXACT [] +synonym: "primary cell septum hydrolysis" EXACT [] +synonym: "primary septum hydrolysis" BROAD [] +is_a: GO:0022411 ! cellular component disassembly +relationship: part_of GO:0000920 ! septum digestion after cytokinesis + +[Term] +id: GO:0030995 +name: cell septum edging catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation." [GOC:mah, PMID:15194814] +synonym: "cell septum edging hydrolysis" EXACT [] +synonym: "hydrolysis of cell septum edging" EXACT [] +synonym: "hydrolysis of edging of cell septum" EXACT [] +synonym: "septum edging hydrolysis" BROAD [] +is_a: GO:0071999 ! extracellular polysaccharide catabolic process +relationship: part_of GO:0000920 ! septum digestion after cytokinesis + +[Term] +id: GO:0030996 +name: obsolete mitotic cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen." [GOC:dph, GOC:mah, GOC:tb, GOC:vw] +comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed. +synonym: "cell cycle arrest in response to nitrogen starvation" BROAD [] +is_obsolete: true + +[Term] +id: GO:0030997 +name: regulation of centriole-centriole cohesion +namespace: biological_process +def: "Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker." [PMID:11076968] +is_a: GO:0046605 ! regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010457 ! centriole-centriole cohesion +relationship: part_of GO:0007098 ! centrosome cycle +relationship: regulates GO:0010457 ! centriole-centriole cohesion + +[Term] +id: GO:0030998 +name: linear element +namespace: cellular_component +def: "A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex." [DOI:10.2323/jgam.28.263, GOC:jb, PMID:12665553, PMID:30640914] +is_a: GO:0099086 ! synaptonemal structure + +[Term] +id: GO:0030999 +name: linear element assembly +namespace: biological_process +def: "The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex." [GOC:jb, GOC:mah, PMID:30640914] +synonym: "linear element formation" RELATED [GOC:dph] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007129 ! synapsis + +[Term] +id: GO:0031000 +name: response to caffeine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them." [GOC:ef, GOC:mah] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0036270 ! response to diuretic +is_a: GO:0043279 ! response to alkaloid + +[Term] +id: GO:0031001 +name: response to brefeldin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus." [GOC:mah] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0031002 +name: actin rod +namespace: cellular_component +def: "A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions." [GOC:kp, GOC:krc, PMID:11858703, PMID:19459188, PMID:22623727, PMID:24813767, PMID:27535426, PMID:7820870] +is_a: GO:0032432 ! actin filament bundle + +[Term] +id: GO:0031003 +name: actin tubule +namespace: cellular_component +def: "A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together." [GOC:kp] +is_a: GO:0032432 ! actin filament bundle +relationship: part_of GO:0031002 ! actin rod + +[Term] +id: GO:0031004 +name: potassium ion-transporting ATPase complex +namespace: cellular_component +def: "Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex." [PMID:10608856, PMID:9858692] +synonym: "Kdp system complex" EXACT [] +is_a: GO:0090533 ! cation-transporting ATPase complex + +[Term] +id: GO:0031005 +name: filamin binding +namespace: molecular_function +alt_id: GO:0031006 +alt_id: GO:0031007 +alt_id: GO:0031008 +def: "Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain." [GOC:mah, PMID:11336782] +synonym: "ABP-278/276 binding" NARROW [] +synonym: "ABP-280 binding" NARROW [] +synonym: "ABPL binding" NARROW [] +synonym: "alpha-filamin binding" NARROW [] +synonym: "beta-filamin binding" NARROW [] +synonym: "filamin A binding" NARROW [] +synonym: "filamin B binding" NARROW [] +synonym: "filamin C binding" EXACT [] +synonym: "filamin-1 binding" NARROW [] +synonym: "filamin-2 binding" NARROW [] +synonym: "filamin-3 binding" NARROW [] +synonym: "filamin-A binding" NARROW [] +synonym: "filamin-B binding" EXACT [] +synonym: "filamin-C binding" NARROW [] +synonym: "gamma-filamin binding" NARROW [] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0031009 +name: plastid ADPG pyrophosphorylase complex +namespace: cellular_component +def: "An ADPG pyrophosphorylase complex found in a plastid." [GOC:mah] +is_a: GO:0030931 ! heterotetrameric ADPG pyrophosphorylase complex +intersection_of: GO:0030929 ! ADPG pyrophosphorylase complex +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0031010 +name: ISWI-type complex +namespace: cellular_component +def: "Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair." [GOC:krc, GOC:mah, PMID:15020051, PMID:15284901, PMID:16568949, PMID:21810179] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex + +[Term] +id: GO:0031011 +name: Ino80 complex +namespace: cellular_component +def: "A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity." [GOC:jh, GOC:rb, PMID:19355820] +synonym: "INO80 chromatin remodeling complex" EXACT [] +is_a: GO:0033202 ! DNA helicase complex +is_a: GO:0097346 ! INO80-type complex + +[Term] +id: GO:0031012 +name: extracellular matrix +namespace: cellular_component +alt_id: GO:0005578 +def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +synonym: "matrisome" NARROW [] +synonym: "proteinaceous extracellular matrix" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090513 +xref: Wikipedia:Extracellular_matrix +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0031013 +name: troponin I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with troponin I, the inhibitory subunit of the troponin complex." [GOC:mah, ISBN:0815316194] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0031014 +name: troponin T binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with troponin T, the tropomyosin-binding subunit of the troponin complex." [GOC:mah, ISBN:0815316194] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0031015 +name: obsolete karyopherin docking complex +namespace: cellular_component +def: "OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p." [PMID:11867631, PMID:9864357] +synonym: "Asm4p-containing complex" NARROW [] +synonym: "karyopherin docking complex" EXACT [] +synonym: "nuclear pore subcomplex" BROAD [] +is_obsolete: true +consider: GO:0017056 +consider: GO:0044613 + +[Term] +id: GO:0031016 +name: pancreas development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes." [GOC:cvs] +xref: Wikipedia:Pancreas +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0031017 +name: exocrine pancreas development +namespace: biological_process +def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0031016 ! pancreas development +relationship: part_of GO:0035272 ! exocrine system development +relationship: part_of GO:0055123 ! digestive system development + +[Term] +id: GO:0031018 +name: endocrine pancreas development +namespace: biological_process +def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0031016 ! pancreas development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0031019 +name: mitochondrial mRNA editing complex +namespace: cellular_component +def: "An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates." [GOC:mah, PMID:12139607] +synonym: "mitochondrial editosome" EXACT [] +is_a: GO:0045293 ! mRNA editing complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0045293 ! mRNA editing complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0031020 +name: plastid mRNA editing complex +namespace: cellular_component +def: "An mRNA editing complex found in a plastid." [GOC:mah] +synonym: "plastid editosome" EXACT [] +is_a: GO:0045293 ! mRNA editing complex +intersection_of: GO:0045293 ! mRNA editing complex +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0031021 +name: interphase microtubule organizing center +namespace: cellular_component +def: "A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus." [PMID:15068790] +synonym: "iMTOC" EXACT [] +synonym: "interphase microtubule organising center" EXACT [] +synonym: "interphase MTOC" EXACT [] +is_a: GO:0005815 ! microtubule organizing center + +[Term] +id: GO:0031022 +name: nuclear migration along microfilament +namespace: biological_process +def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah] +synonym: "nuclear migration, microfilament-mediated" EXACT [] +is_a: GO:0007097 ! nuclear migration +is_a: GO:0030048 ! actin filament-based movement +is_a: GO:0099515 ! actin filament-based transport + +[Term] +id: GO:0031023 +name: microtubule organizing center organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "microtubule organising center organisation" EXACT [] +synonym: "microtubule organizing center organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0031024 +name: interphase microtubule organizing center assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center." [GOC:mah, PMID:15068790] +synonym: "interphase microtubule organising center biosynthesis" EXACT [] +synonym: "interphase microtubule organising center formation" EXACT [] +synonym: "interphase microtubule organizing center biogenesis" RELATED [GOC:mah] +synonym: "interphase microtubule organizing centre assembly" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0031023 ! microtubule organizing center organization + +[Term] +id: GO:0031025 +name: equatorial microtubule organizing center disassembly +namespace: biological_process +def: "The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis." [GOC:mah, PMID:15068790] +synonym: "equatorial microtubule organising center disassembly" EXACT [] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0031023 ! microtubule organizing center organization +is_a: GO:0031121 ! equatorial microtubule organization + +[Term] +id: GO:0031026 +name: glutamate synthase complex +namespace: cellular_component +def: "A complex that possesses glutamate synthase activity." [GOC:mah] +subset: goslim_pir +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031027 +name: glutamate synthase complex (NADH) +namespace: cellular_component +def: "A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity." [GOC:jl, PMID:7047525] +is_a: GO:0031026 ! glutamate synthase complex + +[Term] +id: GO:0031028 +name: septation initiation signaling +namespace: biological_process +def: "The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis." [GOC:mah, GOC:vw, PMID:16775007] +synonym: "septation initiation network" EXACT [] +synonym: "septation initiation signaling cascade" RELATED [GOC:signaling] +synonym: "septation initiation signalling" EXACT [] +synonym: "SIN" EXACT [] +is_a: GO:0007096 ! regulation of exit from mitosis +is_a: GO:0007265 ! Ras protein signal transduction +is_a: GO:0031991 ! regulation of actomyosin contractile ring contraction +is_a: GO:1901893 ! positive regulation of cell septum assembly +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process + +[Term] +id: GO:0031029 +name: regulation of septation initiation signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of septation initiation signaling." [GOC:mah] +synonym: "regulation of septation initiation network" EXACT [] +synonym: "regulation of septation initiation signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of septation initiation signalling" EXACT [] +is_a: GO:0007096 ! regulation of exit from mitosis +is_a: GO:0031991 ! regulation of actomyosin contractile ring contraction +is_a: GO:0046578 ! regulation of Ras protein signal transduction +is_a: GO:1901891 ! regulation of cell septum assembly +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031028 ! septation initiation signaling +relationship: regulates GO:0031028 ! septation initiation signaling + +[Term] +id: GO:0031030 +name: negative regulation of septation initiation signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling." [GOC:mah] +synonym: "down regulation of septation initiation signaling" EXACT [] +synonym: "down-regulation of septation initiation signaling" EXACT [] +synonym: "downregulation of septation initiation signaling" EXACT [] +synonym: "inhibition of septation initiation signaling" NARROW [] +synonym: "negative regulation of septation initiation network" EXACT [] +synonym: "negative regulation of septation initiation signaling cascade" RELATED [GOC:signaling] +synonym: "negative regulation of septation initiation signalling" EXACT [] +is_a: GO:0010974 ! negative regulation of division septum assembly +is_a: GO:0031029 ! regulation of septation initiation signaling +is_a: GO:0046580 ! negative regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031028 ! septation initiation signaling +relationship: negatively_regulates GO:0031028 ! septation initiation signaling + +[Term] +id: GO:0031031 +name: positive regulation of septation initiation signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of septation initiation signaling." [GOC:mah] +synonym: "activation of septation initiation signaling" NARROW [] +synonym: "positive regulation of septation initiation network" EXACT [] +synonym: "positive regulation of septation initiation signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of septation initiation signalling" EXACT [] +synonym: "stimulation of septation initiation signaling" NARROW [] +synonym: "up regulation of septation initiation signaling" EXACT [] +synonym: "up-regulation of septation initiation signaling" EXACT [] +synonym: "upregulation of septation initiation signaling" EXACT [] +is_a: GO:0010973 ! positive regulation of division septum assembly +is_a: GO:0031029 ! regulation of septation initiation signaling +is_a: GO:0046579 ! positive regulation of Ras protein signal transduction +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031028 ! septation initiation signaling +relationship: positively_regulates GO:0031028 ! septation initiation signaling + +[Term] +id: GO:0031032 +name: actomyosin structure organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah] +comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins. +synonym: "actomyosin organization" EXACT [] +synonym: "actomyosin structure organisation" EXACT [] +synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0030036 ! actin cytoskeleton organization + +[Term] +id: GO:0031033 +name: myosin filament organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules." [GOC:mah] +comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins; myosin structures are sufficiently closely associated with actin filaments to be included with the actin cytoskeleton. +synonym: "myosin filament assembly or disassembly" RELATED [GOC:mah] +synonym: "myosin filament organisation" EXACT [GOC:mah] +synonym: "myosin polymerization or depolymerization" RELATED [] +is_a: GO:0030036 ! actin cytoskeleton organization +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0031034 +name: myosin filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a filament composed of myosin molecules." [GOC:mah] +synonym: "myosin polymerization" RELATED [] +is_a: GO:0031033 ! myosin filament organization +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0031035 +name: myosin filament disassembly +namespace: biological_process +def: "The disassembly of a filament composed of myosin molecules." [GOC:mah] +synonym: "myosin depolymerization" RELATED [] +is_a: GO:0031033 ! myosin filament organization +is_a: GO:0043624 ! cellular protein complex disassembly + +[Term] +id: GO:0031036 +name: myosin II filament assembly +namespace: biological_process +def: "The formation of a bipolar filament composed of myosin II molecules." [GOC:mah] +synonym: "myosin II polymerization" RELATED [] +is_a: GO:0031034 ! myosin filament assembly +is_a: GO:0031038 ! myosin II filament organization + +[Term] +id: GO:0031037 +name: myosin II filament disassembly +namespace: biological_process +def: "The disassembly of a bipolar filament composed of myosin II molecules." [GOC:mah] +synonym: "myosin II depolymerization" RELATED [] +is_a: GO:0031035 ! myosin filament disassembly +is_a: GO:0031038 ! myosin II filament organization + +[Term] +id: GO:0031038 +name: myosin II filament organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules." [GOC:mah] +synonym: "myosin II filament assembly or disassembly" RELATED [GOC:mah] +synonym: "myosin II filament organisation" EXACT [GOC:mah] +synonym: "myosin II polymerization or depolymerization" RELATED [] +is_a: GO:0031033 ! myosin filament organization + +[Term] +id: GO:0031039 +name: macronucleus +namespace: cellular_component +def: "A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell." [GOC:ns] +xref: Wikipedia:Macronucleus +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0031040 +name: micronucleus +namespace: cellular_component +def: "A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell." [GOC:ns] +xref: Wikipedia:Micronucleus +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0031041 +name: O-glycan processing, core 5 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0031042 +name: O-glycan processing, core 6 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0031043 +name: O-glycan processing, core 7 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0031044 +name: O-glycan processing, core 8 +namespace: biological_process +def: "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc." [GOC:mah, GOC:pr, PMID:10580130] +is_a: GO:0016266 ! O-glycan processing + +[Term] +id: GO:0031045 +name: dense core granule +namespace: cellular_component +def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495] +synonym: "dense core vesicle" EXACT syngo_official_label [GOC:kmv] +xref: NIF_Subcellular:sao772007592 +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0031047 +name: gene silencing by RNA +namespace: biological_process +def: "Any process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:mah, GOC:tb, PMID:15020054] +synonym: "RNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb] +is_a: GO:0016458 ! gene silencing + +[Term] +id: GO:0031048 +name: heterochromatin assembly by small RNA +namespace: biological_process +alt_id: GO:0070924 +def: "Assembly of heterochromatin, directed by small RNAs sharing sequence identity to the repressed region." [GOC:dph, GOC:mtg_lung, GOC:ns, PMID:19239886] +synonym: "chromatin silencing by small RNA" RELATED [] +synonym: "heterochromatin assembly involved in chromatin silencing by small RNA" RELATED [] +synonym: "heterochromatin formation involved in chromatin silencing by small RNA" RELATED [] +synonym: "RNA interference-like chromatin silencing" EXACT [] +synonym: "RNA-mediated chromatin silencing" EXACT [GOC:dph, GOC:tb] +synonym: "RNA-mediated TGS" BROAD [] +synonym: "RNA-mediated transcriptional silencing" EXACT [] +synonym: "RNAi-directed chromatin silencing" EXACT [GOC:vw] +synonym: "RNAi-like chromatin silencing" EXACT [] +synonym: "small RNA-mediated heterochromatic silencing" EXACT [] +synonym: "small RNA-mediated heterochromatin formation" RELATED [GOC:mah] +is_a: GO:0031507 ! heterochromatin assembly +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-09-11T04:10:51Z + +[Term] +id: GO:0031049 +name: programmed DNA elimination +namespace: biological_process +def: "The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate." [GOC:mah, GOC:ns] +subset: goslim_pir +is_a: GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0031050 +name: dsRNA processing +namespace: biological_process +def: "Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function." [GOC:ns] +synonym: "double-stranded RNA fragmentation" RELATED [] +synonym: "dsRNA fragmentation" RELATED [] +is_a: GO:0006396 ! RNA processing + +[Term] +id: GO:0031051 +name: scnRNA processing +namespace: biological_process +def: "Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome." [PMID:15196465] +synonym: "scnRNA production" BROAD [] +is_a: GO:0031050 ! dsRNA processing +relationship: part_of GO:0031049 ! programmed DNA elimination + +[Term] +id: GO:0031052 +name: chromosome breakage +namespace: biological_process +def: "Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage." [GOC:ns] +comment: Note that this term refers to breakage of chromosomes during normal DNA rearrangements characteristic of ciliates; it is not to be used for DNA damage or other abnormal occurrences. +synonym: "establishment or maintenance of heterochromatin architecture" EXACT [GOC:mah] +is_a: GO:0051276 ! chromosome organization +relationship: part_of GO:0031049 ! programmed DNA elimination + +[Term] +id: GO:0031053 +name: primary miRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule." [GOC:sl, PMID:15211354] +synonym: "pri-miRNA processing" EXACT [] +synonym: "primary microRNA processing" EXACT [] +is_a: GO:0034470 ! ncRNA processing +relationship: part_of GO:0035196 ! production of miRNAs involved in gene silencing by miRNA + +[Term] +id: GO:0031054 +name: pre-miRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule." [GOC:sl, PMID:15211354] +synonym: "pre-microRNA processing" EXACT [] +is_a: GO:0034470 ! ncRNA processing +relationship: part_of GO:0035196 ! production of miRNAs involved in gene silencing by miRNA + +[Term] +id: GO:0031055 +name: chromatin remodeling at centromere +namespace: biological_process +def: "Dynamic structural changes in centromeric DNA." [GOC:mah] +is_a: GO:0006338 ! chromatin remodeling + +[Term] +id: GO:0031056 +name: regulation of histone modification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016570 ! histone modification +relationship: regulates GO:0016570 ! histone modification + +[Term] +id: GO:0031057 +name: negative regulation of histone modification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] +synonym: "down regulation of histone modification" EXACT [] +synonym: "down-regulation of histone modification" EXACT [] +synonym: "downregulation of histone modification" EXACT [] +synonym: "inhibition of histone modification" NARROW [] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016570 ! histone modification +relationship: negatively_regulates GO:0016570 ! histone modification + +[Term] +id: GO:0031058 +name: positive regulation of histone modification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] +synonym: "activation of histone modification" NARROW [] +synonym: "stimulation of histone modification" NARROW [] +synonym: "up regulation of histone modification" EXACT [] +synonym: "up-regulation of histone modification" EXACT [] +synonym: "upregulation of histone modification" EXACT [] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016570 ! histone modification +relationship: positively_regulates GO:0016570 ! histone modification + +[Term] +id: GO:0031059 +name: histone deacetylation at centromere +namespace: biological_process +def: "The removal of acetyl groups from histones in centromeric DNA." [GOC:mah] +is_a: GO:0016575 ! histone deacetylation + +[Term] +id: GO:0031060 +name: regulation of histone methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] +is_a: GO:0031056 ! regulation of histone modification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016571 ! histone methylation +relationship: regulates GO:0016571 ! histone methylation + +[Term] +id: GO:0031061 +name: negative regulation of histone methylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] +synonym: "down regulation of histone methylation" EXACT [] +synonym: "down-regulation of histone methylation" EXACT [] +synonym: "downregulation of histone methylation" EXACT [] +synonym: "inhibition of histone methylation" NARROW [] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016571 ! histone methylation +relationship: negatively_regulates GO:0016571 ! histone methylation + +[Term] +id: GO:0031062 +name: positive regulation of histone methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] +synonym: "activation of histone methylation" NARROW [] +synonym: "stimulation of histone methylation" NARROW [] +synonym: "up regulation of histone methylation" EXACT [] +synonym: "up-regulation of histone methylation" EXACT [] +synonym: "upregulation of histone methylation" EXACT [] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016571 ! histone methylation +relationship: positively_regulates GO:0016571 ! histone methylation + +[Term] +id: GO:0031063 +name: regulation of histone deacetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0090311 ! regulation of protein deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016575 ! histone deacetylation +relationship: regulates GO:0016575 ! histone deacetylation + +[Term] +id: GO:0031064 +name: negative regulation of histone deacetylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] +synonym: "down regulation of histone deacetylation" EXACT [] +synonym: "down-regulation of histone deacetylation" EXACT [] +synonym: "downregulation of histone deacetylation" EXACT [] +synonym: "inhibition of histone deacetylation" NARROW [] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0031063 ! regulation of histone deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016575 ! histone deacetylation +relationship: negatively_regulates GO:0016575 ! histone deacetylation + +[Term] +id: GO:0031065 +name: positive regulation of histone deacetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] +synonym: "activation of histone deacetylation" NARROW [] +synonym: "stimulation of histone deacetylation" NARROW [] +synonym: "up regulation of histone deacetylation" EXACT [] +synonym: "up-regulation of histone deacetylation" EXACT [] +synonym: "upregulation of histone deacetylation" EXACT [] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0031063 ! regulation of histone deacetylation +is_a: GO:0090312 ! positive regulation of protein deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016575 ! histone deacetylation +relationship: positively_regulates GO:0016575 ! histone deacetylation + +[Term] +id: GO:0031066 +name: regulation of histone deacetylation at centromere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA." [GOC:mah] +is_a: GO:0031063 ! regulation of histone deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031059 ! histone deacetylation at centromere +relationship: regulates GO:0031059 ! histone deacetylation at centromere + +[Term] +id: GO:0031067 +name: negative regulation of histone deacetylation at centromere +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA." [GOC:mah] +synonym: "down regulation of histone deacetylation at centromere" EXACT [] +synonym: "down-regulation of histone deacetylation at centromere" EXACT [] +synonym: "downregulation of histone deacetylation at centromere" EXACT [] +synonym: "inhibition of histone deacetylation at centromere" NARROW [] +is_a: GO:0031064 ! negative regulation of histone deacetylation +is_a: GO:0031066 ! regulation of histone deacetylation at centromere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031059 ! histone deacetylation at centromere +relationship: negatively_regulates GO:0031059 ! histone deacetylation at centromere + +[Term] +id: GO:0031068 +name: positive regulation of histone deacetylation at centromere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA." [GOC:mah] +synonym: "activation of histone deacetylation at centromere" NARROW [] +synonym: "stimulation of histone deacetylation at centromere" NARROW [] +synonym: "up regulation of histone deacetylation at centromere" EXACT [] +synonym: "up-regulation of histone deacetylation at centromere" EXACT [] +synonym: "upregulation of histone deacetylation at centromere" EXACT [] +is_a: GO:0031065 ! positive regulation of histone deacetylation +is_a: GO:0031066 ! regulation of histone deacetylation at centromere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031059 ! histone deacetylation at centromere +relationship: positively_regulates GO:0031059 ! histone deacetylation at centromere + +[Term] +id: GO:0031069 +name: hair follicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hair follicle are generated and organized." [GOC:ln] +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0022405 ! hair cycle process +relationship: part_of GO:0001942 ! hair follicle development +relationship: part_of GO:0048730 ! epidermis morphogenesis + +[Term] +id: GO:0031070 +name: intronic snoRNA processing +namespace: biological_process +def: "The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA." [GOC:vw] +is_a: GO:0043144 ! snoRNA processing + +[Term] +id: GO:0031071 +name: cysteine desulfurase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine." [EC:2.8.1.7] +synonym: "cysteine desulfurylase activity" EXACT [EC:2.8.1.7] +synonym: "IscS" RELATED [EC:2.8.1.7] +synonym: "L-cysteine:enzyme cysteine sulfurtransferase activity" EXACT [EC:2.8.1.7] +synonym: "NIFS" RELATED [EC:2.8.1.7] +synonym: "SufS" RELATED [EC:2.8.1.7] +xref: EC:2.8.1.7 +xref: Reactome:R-HSA-1362408 "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster" +xref: Reactome:R-HSA-947514 "NFS1 transfers sulfur from cysteine onto MOCS3" +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0031072 +name: heat shock protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock." [GOC:mah, GOC:vw] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0031073 +name: cholesterol 26-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol." [GOC:mah, PMID:950499] +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0031074 +name: nucleocytoplasmic transport complex +namespace: cellular_component +def: "Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores." [GOC:mah] +subset: gocheck_do_not_annotate +subset: goslim_pir +synonym: "nucleocytoplasmic shuttling complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031076 +name: embryonic camera-type eye development +namespace: biological_process +def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] +synonym: "embryonic eye development" EXACT [] +is_a: GO:0043010 ! camera-type eye development +is_a: GO:0048568 ! embryonic organ development + +[Term] +id: GO:0031077 +name: post-embryonic camera-type eye development +namespace: biological_process +def: "The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] +synonym: "post-embryonic camera-style eye development" EXACT [] +is_a: GO:0043010 ! camera-type eye development +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0009791 ! post-embryonic development + +[Term] +id: GO:0031078 +name: histone deacetylase activity (H3-K14 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein." [EC:3.5.1.17, RHEA:24548] +is_a: GO:0004407 ! histone deacetylase activity +relationship: part_of GO:0070932 ! histone H3 deacetylation + +[Term] +id: GO:0031079 +name: obsolete picornain 3C activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly." [EC:3.4.22.28] +comment: This term was made obsolete because it represents a gene product. +synonym: "3C protease activity" EXACT [EC:3.4.22.28] +synonym: "3C proteinase activity" EXACT [EC:3.4.22.28] +synonym: "coxsackievirus 3C proteinase activity" EXACT [EC:3.4.22.28] +synonym: "cysteine proteinase 3C" RELATED [EC:3.4.22.28] +synonym: "foot-and-mouth protease 3C activity" NARROW [EC:3.4.22.28] +synonym: "foot-and-mouth-disease virus proteinase 3C" RELATED [EC:3.4.22.28] +synonym: "hepatitis A virus 3C proteinase activity" EXACT [EC:3.4.22.28] +synonym: "picornain 3C activity" EXACT [] +synonym: "picornavirus endopeptidase 3C activity" NARROW [EC:3.4.22.28] +synonym: "poliovirus protease 3C activity" NARROW [EC:3.4.22.28] +synonym: "poliovirus proteinase 3C" RELATED [EC:3.4.22.28] +synonym: "protease 3C" RELATED [EC:3.4.22.28] +synonym: "rhinovirus protease 3C activity" NARROW [EC:3.4.22.28] +synonym: "rhinovirus proteinase 3C" RELATED [EC:3.4.22.28] +synonym: "tomato ringspot nepovirus 3C-related protease" RELATED [EC:3.4.22.28] +xref: EC:3.4.22.28 +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0031080 +name: nuclear pore outer ring +namespace: cellular_component +def: "A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates)." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "Nup107-120 complex" EXACT [] +synonym: "Nup107-160 complex" EXACT [] +synonym: "Nup84 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore + +[Term] +id: GO:0031081 +name: nuclear pore distribution +namespace: biological_process +def: "Any process that establishes the spatial arrangement of nuclear pores within the nuclear envelope." [GOC:mah] +synonym: "positioning of nuclear pores" RELATED [] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0051664 ! nuclear pore localization + +[Term] +id: GO:0031082 +name: BLOC complex +namespace: cellular_component +def: "Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex." [PMID:15102850, PMID:15261680] +subset: goslim_pir +synonym: "BLOC-1 related complex" EXACT [PMID:25898167] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0031083 +name: BLOC-1 complex +namespace: cellular_component +def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins." [PMID:15102850] +is_a: GO:0031082 ! BLOC complex + +[Term] +id: GO:0031084 +name: BLOC-2 complex +namespace: cellular_component +def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru." [PMID:12548288, PMID:14718540, PMID:15031569] +is_a: GO:0031082 ! BLOC complex + +[Term] +id: GO:0031085 +name: BLOC-3 complex +namespace: cellular_component +def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins." [PMID:12756248] +is_a: GO:0031082 ! BLOC complex + +[Term] +id: GO:0031086 +name: nuclear-transcribed mRNA catabolic process, deadenylation-independent decay +namespace: biological_process +def: "A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability." [GOC:krc, PMID:15225542, PMID:15225544] +synonym: "deadenylation-independent mRNA decay" EXACT [] +synonym: "deadenylylation-independent mRNA decay" EXACT [] +synonym: "mRNA breakdown, deadenylation-independent decay" EXACT [] +synonym: "mRNA catabolic process, deadenylation-independent" EXACT [] +synonym: "mRNA catabolic process, deadenylylation-independent" EXACT [] +synonym: "mRNA catabolism, deadenylation-independent" EXACT [] +synonym: "mRNA catabolism, deadenylation-independent decay" EXACT [] +synonym: "mRNA catabolism, deadenylylation-independent" EXACT [] +synonym: "mRNA degradation, deadenylation-independent decay" EXACT [] +synonym: "nuclear mRNA catabolic process, deadenylation-independent decay" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0031087 +name: deadenylation-independent decapping of nuclear-transcribed mRNA +namespace: biological_process +def: "Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening." [GOC:krc, PMID:15225542, PMID:15225544] +synonym: "deadenylation-independent decapping of nuclear mRNA" RELATED [] +synonym: "deadenylylation-independent decapping" EXACT [] +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +is_a: GO:0110156 ! methylguanosine-cap decapping +relationship: part_of GO:0031086 ! nuclear-transcribed mRNA catabolic process, deadenylation-independent decay + +[Term] +id: GO:0031088 +name: platelet dense granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the platelet dense granule." [GOC:mah] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042827 ! platelet dense granule + +[Term] +id: GO:0031089 +name: platelet dense granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the platelet dense granule." [GOC:mah] +is_a: GO:0034774 ! secretory granule lumen +relationship: part_of GO:0042827 ! platelet dense granule + +[Term] +id: GO:0031090 +name: organelle membrane +namespace: cellular_component +def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] +synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606] +xref: NIF_Subcellular:sao830981606 +is_a: GO:0016020 ! membrane +relationship: part_of GO:0043227 ! membrane-bounded organelle + +[Term] +id: GO:0031091 +name: platelet alpha granule +namespace: cellular_component +def: "A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG)." [PMID:8467233] +synonym: "platelet alpha-granule" EXACT [] +xref: Wikipedia:Platelet_alpha-granule +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0031092 +name: platelet alpha granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the platelet alpha granule." [GOC:mah, PMID:8467233] +synonym: "platelet alpha-granule membrane" EXACT [] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0031091 ! platelet alpha granule + +[Term] +id: GO:0031093 +name: platelet alpha granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the platelet alpha granule." [GOC:mah, PMID:8467233] +synonym: "platelet alpha-granule lumen" EXACT [] +is_a: GO:0034774 ! secretory granule lumen +relationship: part_of GO:0031091 ! platelet alpha granule + +[Term] +id: GO:0031094 +name: platelet dense tubular network +namespace: cellular_component +def: "A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin." [PMID:1322202] +subset: goslim_pir +is_a: GO:0043231 ! intracellular membrane-bounded organelle + +[Term] +id: GO:0031095 +name: platelet dense tubular network membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the platelet dense tubular network." [GOC:mah, PMID:1322202] +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0031094 ! platelet dense tubular network + +[Term] +id: GO:0031096 +name: platelet dense tubular network lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the platelet dense tubular network." [GOC:mah, PMID:1322202] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0031094 ! platelet dense tubular network + +[Term] +id: GO:0031097 +name: medial cortex +namespace: cellular_component +def: "A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation." [GOC:vw, PMID:15572668, PMID:19474789] +synonym: "medial ring" EXACT [GOC:vw] +is_a: GO:0099738 ! cell cortex region +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0031098 +name: stress-activated protein kinase signaling cascade +namespace: biological_process +def: "A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals." [GOC:mah] +synonym: "JNK signaling pathway" NARROW [] +synonym: "JNK signalling pathway" NARROW [] +synonym: "SAPK signaling pathway" EXACT [] +synonym: "SAPK signalling pathway" EXACT [] +synonym: "stress-activated protein kinase signaling pathway" EXACT [] +synonym: "stress-activated protein kinase signalling pathway" EXACT [] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0031099 +name: regeneration +namespace: biological_process +def: "The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass)." [GOC:mah, GOC:pr] +xref: Wikipedia:Regeneration_(biology) +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0031100 +name: animal organ regeneration +namespace: biological_process +def: "The regrowth of a lost or destroyed animal organ." [GOC:mah] +is_a: GO:0031099 ! regeneration +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0031101 +name: fin regeneration +namespace: biological_process +def: "The regrowth of fin tissue following its loss or destruction." [GOC:dgh] +is_a: GO:0042246 ! tissue regeneration + +[Term] +id: GO:0031102 +name: neuron projection regeneration +namespace: biological_process +def: "The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage." [GOC:dgh, GOC:dph, GOC:tb] +synonym: "neurite regeneration" NARROW [GOC:mah] +is_a: GO:0031099 ! regeneration +is_a: GO:0031175 ! neuron projection development +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0031103 +name: axon regeneration +namespace: biological_process +def: "The regrowth of axons following their loss or damage." [GOC:dgh, GOC:dph, GOC:tb] +is_a: GO:0031102 ! neuron projection regeneration +is_a: GO:0048678 ! response to axon injury +is_a: GO:0061564 ! axon development + +[Term] +id: GO:0031104 +name: dendrite regeneration +namespace: biological_process +def: "The regrowth of dendrites in response to their loss or damage." [GOC:dgh, GOC:dph, GOC:tb] +is_a: GO:0016358 ! dendrite development +is_a: GO:0031102 ! neuron projection regeneration + +[Term] +id: GO:0031105 +name: septin complex +namespace: cellular_component +def: "A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric." [GOC:mah, PMID:15385632] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005938 ! cell cortex +relationship: part_of GO:0032156 ! septin cytoskeleton + +[Term] +id: GO:0031106 +name: septin ring organization +namespace: biological_process +def: "Control of the formation, spatial distribution, and breakdown of the septin ring." [GOC:mah] +synonym: "septin ring organisation" EXACT [] +is_a: GO:0032185 ! septin cytoskeleton organization + +[Term] +id: GO:0031107 +name: septin ring disassembly +namespace: biological_process +def: "The controlled breakdown of a septin ring." [GOC:mah] +is_a: GO:0031106 ! septin ring organization +is_a: GO:1903008 ! organelle disassembly + +[Term] +id: GO:0031108 +name: holo-[acyl-carrier-protein] biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]." [GOC:mlg] +synonym: "holo-[acyl-carrier protein] biosynthesis" EXACT [] +synonym: "holo-[acyl-carrier-protein] anabolism" EXACT [] +synonym: "holo-[acyl-carrier-protein] biosynthesis" EXACT [] +synonym: "holo-[acyl-carrier-protein] formation" EXACT [] +synonym: "holo-[acyl-carrier-protein] synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0019538 ! protein metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0031109 +name: microtubule polymerization or depolymerization +namespace: biological_process +def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0031110 +name: regulation of microtubule polymerization or depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031109 ! microtubule polymerization or depolymerization +relationship: regulates GO:0031109 ! microtubule polymerization or depolymerization + +[Term] +id: GO:0031111 +name: negative regulation of microtubule polymerization or depolymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] +synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] +synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] +synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] +synonym: "inhibition of microtubule polymerization or depolymerization" NARROW [] +is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization +relationship: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization + +[Term] +id: GO:0031112 +name: positive regulation of microtubule polymerization or depolymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] +synonym: "activation of microtubule polymerization or depolymerization" NARROW [] +synonym: "stimulation of microtubule polymerization or depolymerization" NARROW [] +synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] +synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] +synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] +is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization +relationship: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization + +[Term] +id: GO:0031113 +name: regulation of microtubule polymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] +is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization +is_a: GO:0032271 ! regulation of protein polymerization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046785 ! microtubule polymerization +relationship: regulates GO:0046785 ! microtubule polymerization + +[Term] +id: GO:0031114 +name: regulation of microtubule depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] +synonym: "regulation of microtubule disassembly" EXACT [] +is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization +is_a: GO:1901879 ! regulation of protein depolymerization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007019 ! microtubule depolymerization +relationship: regulates GO:0007019 ! microtubule depolymerization + +[Term] +id: GO:0031115 +name: negative regulation of microtubule polymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] +synonym: "down regulation of microtubule polymerization" EXACT [] +synonym: "down-regulation of microtubule polymerization" EXACT [] +synonym: "downregulation of microtubule polymerization" EXACT [] +synonym: "inhibition of microtubule polymerization" NARROW [] +is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization +is_a: GO:0031113 ! regulation of microtubule polymerization +is_a: GO:0032272 ! negative regulation of protein polymerization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046785 ! microtubule polymerization +relationship: negatively_regulates GO:0046785 ! microtubule polymerization + +[Term] +id: GO:0031116 +name: positive regulation of microtubule polymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] +synonym: "activation of microtubule polymerization" NARROW [] +synonym: "stimulation of microtubule polymerization" NARROW [] +synonym: "up regulation of microtubule polymerization" EXACT [] +synonym: "up-regulation of microtubule polymerization" EXACT [] +synonym: "upregulation of microtubule polymerization" EXACT [] +is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization +is_a: GO:0031113 ! regulation of microtubule polymerization +is_a: GO:0032273 ! positive regulation of protein polymerization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046785 ! microtubule polymerization +relationship: positively_regulates GO:0046785 ! microtubule polymerization + +[Term] +id: GO:0031117 +name: positive regulation of microtubule depolymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] +synonym: "activation of microtubule depolymerization" NARROW [] +synonym: "microtubule destabilization" EXACT [] +synonym: "positive regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of microtubule disassembly" EXACT [] +synonym: "stimulation of microtubule depolymerization" NARROW [] +synonym: "up regulation of microtubule depolymerization" EXACT [] +synonym: "up-regulation of microtubule depolymerization" EXACT [] +synonym: "upregulation of microtubule depolymerization" EXACT [] +is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization +is_a: GO:0031114 ! regulation of microtubule depolymerization +is_a: GO:1901881 ! positive regulation of protein depolymerization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007019 ! microtubule depolymerization +relationship: positively_regulates GO:0007019 ! microtubule depolymerization + +[Term] +id: GO:0031118 +name: rRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in an rRNA molecule." [GOC:mah] +is_a: GO:0000154 ! rRNA modification +is_a: GO:0001522 ! pseudouridine synthesis + +[Term] +id: GO:0031119 +name: tRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in a tRNA molecule." [GOC:mah] +is_a: GO:0001522 ! pseudouridine synthesis +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0031120 +name: snRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in an snRNA molecule." [GOC:mah] +is_a: GO:0001522 ! pseudouridine synthesis +is_a: GO:0040031 ! snRNA modification + +[Term] +id: GO:0031121 +name: equatorial microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell." [GOC:mah, GOC:vw] +synonym: "equatorial microtubule organisation" EXACT [] +synonym: "equatorial microtubule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0031122 +name: cytoplasmic microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah] +synonym: "cytoplasmic microtubule organisation" EXACT [] +synonym: "cytoplasmic microtubule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0031123 +name: RNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an RNA molecule." [GOC:mah] +synonym: "RNA 3' end processing" EXACT [] +is_a: GO:0006396 ! RNA processing + +[Term] +id: GO:0031124 +name: mRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an mRNA molecule." [GOC:mah] +synonym: "mRNA 3' end processing" EXACT [] +is_a: GO:0006397 ! mRNA processing +is_a: GO:0031123 ! RNA 3'-end processing + +[Term] +id: GO:0031125 +name: rRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an rRNA molecule." [GOC:mah] +synonym: "rRNA 3' end processing" EXACT [] +is_a: GO:0006364 ! rRNA processing +is_a: GO:0043628 ! ncRNA 3'-end processing + +[Term] +id: GO:0031126 +name: snoRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a snoRNA molecule." [GOC:mah] +synonym: "snoRNA 3' end processing" EXACT [] +is_a: GO:0043144 ! snoRNA processing +is_a: GO:0043628 ! ncRNA 3'-end processing + +[Term] +id: GO:0031127 +name: alpha-(1,2)-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage." [GOC:mah] +synonym: "alpha-(1->2)-fucosyltransferase activity" EXACT [] +synonym: "alpha-1,2-fucosyltransferase activity" EXACT [] +is_a: GO:0008417 ! fucosyltransferase activity + +[Term] +id: GO:0031128 +name: developmental induction +namespace: biological_process +def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535] +is_a: GO:0032502 ! developmental process +intersection_of: GO:0032502 ! developmental process +intersection_of: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment +relationship: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0031129 +name: inductive cell-cell signaling +namespace: biological_process +def: "Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate." [GOC:mah] +synonym: "inductive cell-cell signalling" EXACT [] +is_a: GO:0031128 ! developmental induction + +[Term] +id: GO:0031130 +name: creation of an inductive signal +namespace: biological_process +def: "The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter." [GOC:mah] +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0031129 ! inductive cell-cell signaling + +[Term] +id: GO:0031131 +name: reception of an inductive signal +namespace: biological_process +def: "The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change." [GOC:mah] +is_a: GO:0031668 ! cellular response to extracellular stimulus +relationship: part_of GO:0031129 ! inductive cell-cell signaling + +[Term] +id: GO:0031132 +name: serine 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH." [EC:1.1.1.276, RHEA:21596] +synonym: "L-serine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.276] +xref: EC:1.1.1.276 +xref: KEGG_REACTION:R06126 +xref: MetaCyc:RXN0-2201 +xref: RHEA:21596 +xref: Wikipedia:Serine_3-dehydrogenase +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0031133 +name: regulation of axon diameter +namespace: biological_process +def: "Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained." [GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0032536 ! regulation of cell projection size +is_a: GO:0050770 ! regulation of axonogenesis + +[Term] +id: GO:0031134 +name: sister chromatid biorientation +namespace: biological_process +def: "The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles." [PMID:15309047] +synonym: "chromosome biorientation" EXACT [] +synonym: "sister kinetochore biorientation" EXACT [] +is_a: GO:0008608 ! attachment of spindle microtubules to kinetochore +relationship: part_of GO:0000819 ! sister chromatid segregation + +[Term] +id: GO:0031135 +name: negative regulation of conjugation +namespace: biological_process +def: "Any process that decreases the rate of conjugation." [GOC:mah] +synonym: "down regulation of conjugation" EXACT [] +synonym: "down-regulation of conjugation" EXACT [] +synonym: "downregulation of conjugation" EXACT [] +synonym: "inhibition of conjugation" NARROW [] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0046999 ! regulation of conjugation +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000746 ! conjugation +relationship: negatively_regulates GO:0000746 ! conjugation + +[Term] +id: GO:0031136 +name: positive regulation of conjugation +namespace: biological_process +def: "Any process that increases the rate or frequency of conjugation." [GOC:mah] +synonym: "activation of conjugation" NARROW [] +synonym: "stimulation of conjugation" NARROW [] +synonym: "up regulation of conjugation" EXACT [] +synonym: "up-regulation of conjugation" EXACT [] +synonym: "upregulation of conjugation" EXACT [] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0046999 ! regulation of conjugation +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000746 ! conjugation +relationship: positively_regulates GO:0000746 ! conjugation + +[Term] +id: GO:0031137 +name: regulation of conjugation with cellular fusion +namespace: biological_process +def: "Any process that modulates the rate or frequency of conjugation with cellular fusion." [GOC:mah] +is_a: GO:0046999 ! regulation of conjugation +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000747 ! conjugation with cellular fusion +relationship: regulates GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0031138 +name: negative regulation of conjugation with cellular fusion +namespace: biological_process +def: "Any process that decreases the rate or frequency of conjugation with cellular fusion." [GOC:mah] +synonym: "down regulation of conjugation with cellular fusion" EXACT [] +synonym: "down-regulation of conjugation with cellular fusion" EXACT [] +synonym: "downregulation of conjugation with cellular fusion" EXACT [] +synonym: "inhibition of conjugation with cellular fusion" NARROW [] +is_a: GO:0031135 ! negative regulation of conjugation +is_a: GO:0031137 ! regulation of conjugation with cellular fusion +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000747 ! conjugation with cellular fusion +relationship: negatively_regulates GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0031139 +name: positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "Any process that increases the rate or frequency of conjugation with cellular fusion." [GOC:mah] +synonym: "activation of conjugation with cellular fusion" NARROW [] +synonym: "stimulation of conjugation with cellular fusion" NARROW [] +synonym: "up regulation of conjugation with cellular fusion" EXACT [] +synonym: "up-regulation of conjugation with cellular fusion" EXACT [] +synonym: "upregulation of conjugation with cellular fusion" EXACT [] +is_a: GO:0031136 ! positive regulation of conjugation +is_a: GO:0031137 ! regulation of conjugation with cellular fusion +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000747 ! conjugation with cellular fusion +relationship: positively_regulates GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0031140 +name: induction of conjugation upon nutrient starvation +namespace: biological_process +def: "The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients." [GOC:mah] +is_a: GO:0010514 ! induction of conjugation with cellular fusion + +[Term] +id: GO:0031141 +name: induction of conjugation upon carbon starvation +namespace: biological_process +def: "The process in which a cell initiates conjugation with cellular fusion upon carbon starvation." [GOC:mah] +is_a: GO:0031140 ! induction of conjugation upon nutrient starvation + +[Term] +id: GO:0031142 +name: induction of conjugation upon nitrogen starvation +namespace: biological_process +def: "The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation." [GOC:mah] +is_a: GO:0006995 ! cellular response to nitrogen starvation +is_a: GO:0031140 ! induction of conjugation upon nutrient starvation + +[Term] +id: GO:0031143 +name: pseudopodium +namespace: cellular_component +def: "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." [ISBN:0198506732] +subset: goslim_pir +synonym: "pseudopod" EXACT [] +xref: Wikipedia:Pseudopod +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0031144 +name: proteasome localization +namespace: biological_process +def: "Any process in which the proteasome is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of proteasome localization" EXACT [] +synonym: "proteasome localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization + +[Term] +id: GO:0031145 +name: anaphase-promoting complex-dependent catabolic process +namespace: biological_process +alt_id: GO:0008054 +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome." [GOC:mah, PMID:15380083, PMID:15840442] +synonym: "anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein breakdown" EXACT [] +synonym: "anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism" EXACT [] +synonym: "anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein degradation" EXACT [] +synonym: "APC-dependent proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "APC-dependent proteasomal ubiquitin-dependent protein catabolism" EXACT [] +synonym: "cyclin breakdown" NARROW [] +synonym: "cyclin catabolic process" NARROW [] +synonym: "cyclin catabolism" NARROW [] +synonym: "cyclin degradation" NARROW [] +synonym: "degradation of cyclin" NARROW [] +synonym: "negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation" NARROW [] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0031146 +name: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome." [PMID:15380083] +synonym: "SCF-dependent proteasomal ubiquitin-dependent protein breakdown" EXACT [] +synonym: "SCF-dependent proteasomal ubiquitin-dependent protein catabolism" EXACT [] +synonym: "SCF-dependent proteasomal ubiquitin-dependent protein degradation" EXACT [] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0031147 +name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells." [GOC:mah, PMID:10706822] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolism" EXACT [] +synonym: "DIF-1 metabolic process" EXACT [] +synonym: "DIF-1 metabolism" EXACT [] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0031148 +name: DIF-1 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells." [GOC:mah, PMID:10706822] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one anabolism" EXACT [] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthesis" EXACT [] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthetic process" EXACT [] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one formation" EXACT [] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one synthesis" EXACT [] +synonym: "DIF-1 biosynthesis" EXACT [] +is_a: GO:0031147 ! 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0031149 +name: sorocarp stalk cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640, PMID:4338436] +synonym: "stalk cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0031150 ! sorocarp stalk development + +[Term] +id: GO:0031150 +name: sorocarp stalk development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum." [GOC:mtg_sensu, ISBN:0521583640, PMID:4338436] +synonym: "sorophore development" EXACT [] +synonym: "stalk development" BROAD [] +synonym: "stalk formation" BROAD [] +is_a: GO:0099120 ! socially cooperative development +relationship: part_of GO:0031154 ! culmination involved in sorocarp development + +[Term] +id: GO:0031151 +name: histone methyltransferase activity (H3-K79 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein." [GOC:mah, PMID:15371351] +synonym: "histone lysine N-methyltransferase activity (H3-K79 specific)" EXACT [] +synonym: "histone methylase activity (H3-K79 specific)" EXACT [GOC:mah] +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0034729 ! histone H3-K79 methylation + +[Term] +id: GO:0031152 +name: aggregation involved in sorocarp development +namespace: biological_process +def: "The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640] +synonym: "aggregate development involved in sorocarp development" EXACT [] +synonym: "aggregation during fruiting body development" EXACT [] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0099120 ! socially cooperative development +relationship: part_of GO:0030587 ! sorocarp development + +[Term] +id: GO:0031153 +name: slug development involved in sorocarp development +namespace: biological_process +def: "The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640] +synonym: "migratory slug development during sorocarp development" NARROW [] +synonym: "pseudoplasmodium biosynthesis" EXACT [] +synonym: "pseudoplasmodium formation" EXACT [] +synonym: "slug development during fruiting body development" EXACT [] +synonym: "slug development during sorocarp development" RELATED [GOC:dph, GOC:tb] +synonym: "standing slug development during sorocarp development" NARROW [] +is_a: GO:0099120 ! socially cooperative development +relationship: part_of GO:0030587 ! sorocarp development + +[Term] +id: GO:0031154 +name: culmination involved in sorocarp development +namespace: biological_process +def: "The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development." [GOC:mah, GOC:mtg_sensu, ISBN:0521583640] +synonym: "culminant development" EXACT [] +synonym: "culmination during fruiting body development" EXACT [] +synonym: "culmination during sorocarp development" RELATED [] +is_a: GO:0099120 ! socially cooperative development +relationship: part_of GO:0030587 ! sorocarp development + +[Term] +id: GO:0031155 +name: regulation of reproductive fruiting body development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reproductive fruiting body development." [GOC:mah] +synonym: "regulation of fruiting body formation" EXACT [] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030582 ! reproductive fruiting body development +relationship: regulates GO:0030582 ! reproductive fruiting body development + +[Term] +id: GO:0031156 +name: regulation of sorocarp development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum." [GOC:mah, GOC:mtg_sensu, PMID:4332228] +synonym: "regulation of fruiting body development" BROAD [] +synonym: "regulation of fruiting body formation" BROAD [] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030587 ! sorocarp development +relationship: regulates GO:0030587 ! sorocarp development + +[Term] +id: GO:0031157 +name: regulation of aggregate size involved in sorocarp development +namespace: biological_process +def: "Any process that modulates the size of the aggregate formed during sorocarp formation." [GOC:mah, GOC:mtg_sensu, GOC:pg, PMID:4338436] +synonym: "regulation of aggregation during fruiting body biosynthesis" RELATED [] +synonym: "regulation of aggregation during fruiting body formation" RELATED [] +is_a: GO:0060176 ! regulation of aggregation involved in sorocarp development +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0031158 +name: negative regulation of aggregate size involved in sorocarp development +namespace: biological_process +def: "Any process that decreases the size of the aggregate formed during sorocarp formation." [GOC:mah, GOC:mtg_sensu, GOC:pg, PMID:5002049] +synonym: "down regulation of aggregate size" EXACT [] +synonym: "down-regulation of aggregate size" EXACT [] +synonym: "downregulation of aggregate size" EXACT [] +synonym: "inhibition of aggregate size" NARROW [] +is_a: GO:0031157 ! regulation of aggregate size involved in sorocarp development + +[Term] +id: GO:0031159 +name: positive regulation of aggregate size involved in sorocarp development +namespace: biological_process +def: "Any process that increases the size of the aggregate formed during sorocarp formation." [GOC:mah, GOC:pg, PMID:5002049] +synonym: "activation of aggregate size" NARROW [] +synonym: "stimulation of aggregate size" NARROW [] +synonym: "up regulation of aggregate size" EXACT [] +synonym: "up-regulation of aggregate size" EXACT [] +synonym: "upregulation of aggregate size" EXACT [] +is_a: GO:0031157 ! regulation of aggregate size involved in sorocarp development + +[Term] +id: GO:0031160 +name: spore wall +namespace: cellular_component +def: "The specialized envelope lying outside the cell membrane of a spore." [GOC:mah, GOC:pg] +synonym: "spore coat" EXACT [] +is_a: GO:0005618 ! cell wall + +[Term] +id: GO:0031161 +name: phosphatidylinositol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [GOC:mah] +synonym: "phosphatidylinositol breakdown" EXACT [] +synonym: "phosphatidylinositol catabolism" EXACT [] +synonym: "phosphatidylinositol degradation" EXACT [] +synonym: "PtdIns catabolic process" EXACT [] +synonym: "PtdIns catabolism" EXACT [] +is_a: GO:0046475 ! glycerophospholipid catabolic process +is_a: GO:0046488 ! phosphatidylinositol metabolic process + +[Term] +id: GO:0031162 +name: sulfur incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of exogenous sulfur into a metallo-sulfur cluster." [GOC:mah] +synonym: "sulphur incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0006790 ! sulfur compound metabolic process +relationship: part_of GO:0031163 ! metallo-sulfur cluster assembly + +[Term] +id: GO:0031163 +name: metallo-sulfur cluster assembly +namespace: biological_process +def: "The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster." [GOC:jl, GOC:mah, GOC:pde, GOC:vw] +synonym: "metal-sulfur cluster assembly" EXACT [GOC:pr] +synonym: "metallo-sulfur cluster biosynthesis" RELATED [] +synonym: "metallo-sulphur cluster assembly" EXACT [] +is_a: GO:0022607 ! cellular component assembly + +[Term] +id: GO:0031164 +name: contractile vacuolar membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the contractile vacuole." [GOC:pg] +synonym: "contractile vacuole membrane" EXACT [GOC:mah, GOC:pf] +is_a: GO:0005774 ! vacuolar membrane +relationship: part_of GO:0000331 ! contractile vacuole + +[Term] +id: GO:0031165 +name: integral component of contractile vacuolar membrane +namespace: cellular_component +def: "The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer." [GOC:dos, GOC:pg] +synonym: "integral to contractile vacuolar membrane" EXACT [] +is_a: GO:0031166 ! integral component of vacuolar membrane +is_a: GO:0031311 ! intrinsic component of contractile vacuolar membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0031164 ! contractile vacuolar membrane + +[Term] +id: GO:0031166 +name: integral component of vacuolar membrane +namespace: cellular_component +def: "The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:dos, GOC:mah] +synonym: "integral to vacuolar membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0031310 ! intrinsic component of vacuolar membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0031167 +name: rRNA methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule." [GOC:mah] +is_a: GO:0000154 ! rRNA modification +is_a: GO:0001510 ! RNA methylation + +[Term] +id: GO:0031168 +name: ferrichrome metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:mah, ISBN:0198506732] +synonym: "ferrichrome metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0009237 ! siderophore metabolic process + +[Term] +id: GO:0031169 +name: ferrichrome biosynthetic process +namespace: biological_process +alt_id: GO:0031199 +alt_id: GO:0031200 +def: "The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:mah, ISBN:0198506732] +synonym: "ferrichrome anabolism" EXACT [] +synonym: "ferrichrome biosynthesis" EXACT [] +synonym: "ferrichrome biosynthetic process, peptide formation" NARROW [] +synonym: "ferrichrome biosynthetic process, peptide modification" NARROW [] +synonym: "ferrichrome formation" EXACT [] +synonym: "ferrichrome synthesis" EXACT [] +is_a: GO:0019539 ! siderophore biosynthetic process from hydroxamic acid +is_a: GO:0031168 ! ferrichrome metabolic process + +[Term] +id: GO:0031170 +name: ferricrocin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3." [GOC:mah, PMID:12828635] +synonym: "ferricrocin metabolism" EXACT [] +is_a: GO:0031168 ! ferrichrome metabolic process + +[Term] +id: GO:0031171 +name: ferricrocin biosynthetic process +namespace: biological_process +alt_id: GO:0031185 +alt_id: GO:0031186 +def: "The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3." [GOC:mah, PMID:12828635] +synonym: "ferricrocin anabolism" EXACT [] +synonym: "ferricrocin biosynthesis" EXACT [] +synonym: "ferricrocin biosynthetic process, peptide formation" NARROW [] +synonym: "ferricrocin biosynthetic process, peptide modification" NARROW [] +synonym: "ferricrocin formation" EXACT [] +synonym: "ferricrocin synthesis" EXACT [] +is_a: GO:0031169 ! ferrichrome biosynthetic process +is_a: GO:0031170 ! ferricrocin metabolic process + +[Term] +id: GO:0031172 +name: ornithine N5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O." [MetaCyc:RXN-11128, PMID:12828635] +synonym: "L-ornithine 5-monooxygenase activity" EXACT [MetaCyc:RXN-11128] +xref: MetaCyc:RXN-11128 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0031173 +name: otolith mineralization completed early in development +namespace: biological_process +def: "The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear." [GOC:dsf, PMID:15581873] +synonym: "otoconia mineralization" EXACT [] +synonym: "otoconium mineralization" EXACT [] +is_a: GO:0045299 ! otolith mineralization + +[Term] +id: GO:0031174 +name: lifelong otolith mineralization +namespace: biological_process +def: "The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added." [GOC:dsf, PMID:15581873] +is_a: GO:0045299 ! otolith mineralization + +[Term] +id: GO:0031175 +name: neuron projection development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah] +synonym: "neurite biosynthesis" NARROW [] +synonym: "neurite development" NARROW [GOC:dph] +synonym: "neurite formation" NARROW [] +synonym: "neurite growth" NARROW [] +synonym: "neurite outgrowth" NARROW [] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization +intersection_of: part_of GO:0048666 ! neuron development +relationship: part_of GO:0048666 ! neuron development + +[Term] +id: GO:0031176 +name: endo-1,4-beta-xylanase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans." [EC:3.2.1.8] +synonym: "1,4-beta-D-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] +synonym: "1,4-beta-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] +synonym: "beta-1,4-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] +synonym: "beta-1,4-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "beta-D-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "beta-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity" EXACT [EC:3.2.1.8] +synonym: "endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity" EXACT [EC:3.2.1.8] +synonym: "endo-1,4-beta-D-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "endo-1,4-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "endo-beta-1,4-xylanase activity" EXACT [EC:3.2.1.8] +synonym: "xylanase" BROAD [EC:3.2.1.8] +xref: EC:3.2.1.8 +xref: MetaCyc:3.2.1.8-RXN +is_a: GO:0097599 ! xylanase activity + +[Term] +id: GO:0031177 +name: phosphopantetheine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate)." [GOC:mah, GOC:vw] +is_a: GO:0019842 ! vitamin binding +is_a: GO:0033218 ! amide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0048037 ! cofactor binding +is_a: GO:0072341 ! modified amino acid binding + +[Term] +id: GO:0031179 +name: peptide modification +namespace: biological_process +def: "The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide." [GOC:mah] +is_a: GO:0006518 ! peptide metabolic process + +[Term] +id: GO:0031201 +name: SNARE complex +namespace: cellular_component +def: "A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25." [GOC:bhm, GOC:pr, PMID:10872468, PMID:19450911] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031203 +name: posttranslational protein targeting to membrane, docking +namespace: biological_process +def: "The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex." [PMID:12518217, PMID:8707814] +synonym: "posttranslational protein membrane targeting, docking" EXACT [] +synonym: "protein docking during posttranslational protein targeting to membrane" EXACT [] +synonym: "Sec-translated protein complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0006620 ! posttranslational protein targeting to endoplasmic reticulum membrane + +[Term] +id: GO:0031204 +name: posttranslational protein targeting to membrane, translocation +namespace: biological_process +def: "The process in which a protein translocates through the ER membrane posttranslationally." [PMID:12518317, PMID:8707814] +synonym: "posttranslational protein membrane targeting, translocation" EXACT [] +synonym: "protein translocation during posttranslational protein targeting to membrane" EXACT [] +is_a: GO:0065002 ! intracellular protein transmembrane transport +relationship: part_of GO:0006620 ! posttranslational protein targeting to endoplasmic reticulum membrane + +[Term] +id: GO:0031205 +name: endoplasmic reticulum Sec complex +namespace: cellular_component +def: "An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex." [GOC:mtg_sensu, PMID:12158317, PMID:14617809] +subset: goslim_pir +is_a: GO:0098796 ! membrane protein complex +relationship: has_part GO:0005784 ! Sec61 translocon complex +relationship: part_of GO:0030867 ! rough endoplasmic reticulum membrane + +[Term] +id: GO:0031207 +name: Sec62/Sec63 complex +namespace: cellular_component +def: "A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p." [PMID:12518317, PMID:14617809] +synonym: "ER protein translocation subcomplex" EXACT [] +synonym: "Sec62/63 complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0031205 ! endoplasmic reticulum Sec complex + +[Term] +id: GO:0031208 +name: POZ domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors." [PMID:7958847] +synonym: "broad-complex, tramtrack, and bric-a-brac domain binding" EXACT [] +synonym: "BTB domain" EXACT [PMID:22621901] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0031209 +name: SCAR complex +namespace: cellular_component +def: "A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction." [GOC:hla, GOC:pg, PMID:12181570, PMID:24036345, PMID:24630101] +synonym: "WAVE complex" EXACT [] +synonym: "WAVE regulatory complex" EXACT [] +synonym: "WRC" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031210 +name: phosphatidylcholine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:mah, ISBN:0198506732] +is_a: GO:0005543 ! phospholipid binding +is_a: GO:0043169 ! cation binding +is_a: GO:0050997 ! quaternary ammonium group binding + +[Term] +id: GO:0031211 +name: endoplasmic reticulum palmitoyltransferase complex +namespace: cellular_component +def: "A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue." [GOC:jh] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1905961 ! protein-cysteine S-palmitoyltransferase complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0031213 +name: RSF complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters)." [GOC:krc, PMID:12972596, PMID:15284901, PMID:16568949, PMID:21810179] +synonym: "remodeling and spacing factor complex" EXACT [] +is_a: GO:0031010 ! ISWI-type complex + +[Term] +id: GO:0031214 +name: biomineral tissue development +namespace: biological_process +def: "Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation." [PMID:15132736] +xref: Wikipedia:Biomineralization +is_a: GO:0009888 ! tissue development +is_a: GO:0110148 ! biomineralization +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0031215 +name: shell calcification +namespace: biological_process +def: "The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell." [GOC:mah, PMID:15132736] +is_a: GO:0031214 ! biomineral tissue development + +[Term] +id: GO:0031216 +name: neopullulanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose)." [EC:3.2.1.135, GOC:mlg] +synonym: "pullulan 4-D-glucanohydrolase (panose-forming)" EXACT [EC:3.2.1.135] +synonym: "pullulanase II activity" EXACT [] +xref: EC:3.2.1.135 +xref: MetaCyc:3.2.1.135-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0031217 +name: glucan 1,4-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units." [EC:3.2.1.74, GOC:mlg] +synonym: "1,4-beta-D-glucan glucohydrolase activity" BROAD [EC:3.2.1.74] +synonym: "beta-1,4-beta-glucanase activity" BROAD [EC:3.2.1.74] +synonym: "beta-1,4-glucanase activity" BROAD [] +synonym: "exo-1,4-beta-D-glucosidase activity" EXACT [EC:3.2.1.74] +synonym: "exo-1,4-beta-glucanase activity" EXACT [] +synonym: "exo-1,4-beta-glucosidase activity" EXACT [] +synonym: "exo-beta-1,4-glucanase activity" EXACT [] +synonym: "exo-beta-1,4-glucosidase activity" EXACT [] +synonym: "exocellulase activity" EXACT [] +xref: EC:3.2.1.74 +xref: MetaCyc:3.2.1.74-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0031218 +name: arabinogalactan endo-1,4-beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans." [EC:3.2.1.89, GOC:mlg] +synonym: "arabinogalactan 4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.89] +synonym: "arabinogalactanase activity" EXACT [] +synonym: "endo-1,4-beta-galactanase activity" EXACT [] +synonym: "galactanase activity" EXACT [] +xref: EC:3.2.1.89 +xref: MetaCyc:3.2.1.89-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0031219 +name: levanase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units." [EC:3.2.1.65, GOC:mlg] +synonym: "2,6-beta-D-fructan fructanohydrolase activity" EXACT [EC:3.2.1.65] +synonym: "levan hydrolase activity" EXACT [] +xref: EC:3.2.1.65 +xref: MetaCyc:3.2.1.65-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0031220 +name: maltodextrin phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: maltodextrin = glucose-1-phosphate." [GOC:mlg, PMID:10348846] +xref: MetaCyc:RXN-9025 +xref: MetaCyc:RXN0-5182 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0031221 +name: arabinan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues." [GOC:mlg, ISBN:0198506732] +synonym: "arabinan metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0031222 +name: arabinan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues." [GOC:mlg, ISBN:0198506732] +synonym: "arabinan breakdown" EXACT [] +synonym: "arabinan catabolism" EXACT [] +synonym: "arabinan degradation" EXACT [] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0031221 ! arabinan metabolic process + +[Term] +id: GO:0031223 +name: auditory behavior +namespace: biological_process +def: "The behavior of an organism in response to a sound." [GOC:pr, GOC:rc] +synonym: "auditory behaviour" EXACT [] +synonym: "behavioral response to sound" EXACT [] +synonym: "behavioural response to sound" EXACT [] +is_a: GO:0007638 ! mechanosensory behavior +relationship: part_of GO:0010996 ! response to auditory stimulus + +[Term] +id: GO:0031224 +name: intrinsic component of membrane +namespace: cellular_component +def: "The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane." [GOC:mah] +comment: Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent. +subset: goslim_metagenomics +synonym: "intrinsic to membrane" NARROW [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016020 ! membrane + +[Term] +id: GO:0031225 +name: anchored component of membrane +namespace: cellular_component +def: "The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:mah] +synonym: "anchored to membrane" EXACT [] +is_a: GO:0031224 ! intrinsic component of membrane + +[Term] +id: GO:0031226 +name: intrinsic component of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to plasma membrane" NARROW [] +is_a: GO:0031224 ! intrinsic component of membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0031227 +name: intrinsic component of endoplasmic reticulum membrane +namespace: cellular_component +def: "The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to endoplasmic reticulum membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005789 ! endoplasmic reticulum membrane +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0031228 +name: intrinsic component of Golgi membrane +namespace: cellular_component +def: "The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to Golgi membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0000139 ! Golgi membrane +relationship: part_of GO:0000139 ! Golgi membrane + +[Term] +id: GO:0031229 +name: intrinsic component of nuclear inner membrane +namespace: cellular_component +def: "The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to nuclear inner membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005637 ! nuclear inner membrane +relationship: part_of GO:0005637 ! nuclear inner membrane + +[Term] +id: GO:0031230 +name: intrinsic component of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "intrinsic to cell outer membrane" NARROW [] +is_a: GO:0031224 ! intrinsic component of membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0009279 ! cell outer membrane +relationship: part_of GO:0009279 ! cell outer membrane + +[Term] +id: GO:0031231 +name: intrinsic component of peroxisomal membrane +namespace: cellular_component +def: "The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to peroxisomal membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005778 ! peroxisomal membrane +relationship: part_of GO:0005778 ! peroxisomal membrane + +[Term] +id: GO:0031232 +name: extrinsic component of external side of plasma membrane +namespace: cellular_component +def: "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to external leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "extrinsic to external side of plasma membrane" NARROW [] +is_a: GO:0019897 ! extrinsic component of plasma membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0009897 ! external side of plasma membrane +relationship: part_of GO:0009897 ! external side of plasma membrane + +[Term] +id: GO:0031233 +name: intrinsic component of external side of plasma membrane +namespace: cellular_component +def: "The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah] +synonym: "intrinsic to external leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "intrinsic to external side of plasma membrane" NARROW [] +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: part_of GO:0009897 ! external side of plasma membrane +relationship: part_of GO:0009897 ! external side of plasma membrane + +[Term] +id: GO:0031234 +name: extrinsic component of cytoplasmic side of plasma membrane +namespace: cellular_component +def: "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region." [GOC:mah] +comment: Consider also annotating to 'cell cortex ; GO:0005938'. +synonym: "extrinsic to cytoplasmic side of plasma membrane" NARROW [] +synonym: "extrinsic to internal leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "extrinsic to internal side of plasma membrane" EXACT [] +is_a: GO:0019897 ! extrinsic component of plasma membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0009898 ! cytoplasmic side of plasma membrane +relationship: part_of GO:0005622 ! intracellular +relationship: part_of GO:0009898 ! cytoplasmic side of plasma membrane + +[Term] +id: GO:0031235 +name: intrinsic component of the cytoplasmic side of the plasma membrane +namespace: cellular_component +def: "The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only." [GOC:dos, GOC:mah] +synonym: "intrinsic to cytoplasmic side of plasma membrane" NARROW [] +synonym: "intrinsic to internal leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "intrinsic to internal side of plasma membrane" EXACT [] +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0009898 ! cytoplasmic side of plasma membrane +relationship: part_of GO:0009898 ! cytoplasmic side of plasma membrane + +[Term] +id: GO:0031236 +name: extrinsic component of periplasmic side of plasma membrane +namespace: cellular_component +alt_id: GO:0031238 +def: "The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "extrinsic to external leaflet of plasma membrane, in periplasmic space" NARROW [GOC:ab] +synonym: "extrinsic to external side of plasma membrane, in periplasmic space" NARROW [] +is_a: GO:0031232 ! extrinsic component of external side of plasma membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098567 ! periplasmic side of plasma membrane +relationship: part_of GO:0098567 ! periplasmic side of plasma membrane + +[Term] +id: GO:0031237 +name: intrinsic component of periplasmic side of plasma membrane +namespace: cellular_component +alt_id: GO:0031239 +def: "The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:mah, GOC:mtg_sensu] +synonym: "intrinsic to external leaflet of plasma membrane, in periplasmic space" EXACT [GOC:ab] +synonym: "intrinsic to periplasmic side of plasma membrane" EXACT [] +is_a: GO:0031233 ! intrinsic component of external side of plasma membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098567 ! periplasmic side of plasma membrane +relationship: part_of GO:0098567 ! periplasmic side of plasma membrane + +[Term] +id: GO:0031240 +name: external side of cell outer membrane +namespace: cellular_component +def: "The side of the outer membrane that is opposite to the side that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu] +comment: In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane. +synonym: "external leaflet of cell outer membrane" EXACT [GOC:ab] +synonym: "external side of outer membrane" RELATED [] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0009279 ! cell outer membrane + +[Term] +id: GO:0031241 +name: periplasmic side of cell outer membrane +namespace: cellular_component +def: "The side (leaflet) of the outer membrane that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu] +comment: In GO, 'internal side' still refers to part of the membrane and does not refer to components beyond (inside of) the membrane. +synonym: "internal leaflet of cell outer membrane" EXACT [GOC:ab] +synonym: "internal side of cell outer membrane" EXACT [] +synonym: "internal side of outer membrane" EXACT [] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0009279 ! cell outer membrane + +[Term] +id: GO:0031242 +name: extrinsic component of external side of cell outer membrane +namespace: cellular_component +def: "The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "extrinsic to external leaflet of cell outer membrane" EXACT [GOC:ab] +synonym: "extrinsic to external side of cell outer membrane" NARROW [] +synonym: "extrinsic to external side of outer membrane" EXACT [] +is_a: GO:0031244 ! extrinsic component of cell outer membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0031240 ! external side of cell outer membrane +relationship: part_of GO:0031240 ! external side of cell outer membrane + +[Term] +id: GO:0031243 +name: intrinsic component of external side of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "intrinsic to external leaflet of cell outer membrane" EXACT [GOC:ab] +synonym: "intrinsic to external side of cell outer membrane" NARROW [] +synonym: "intrinsic to external side of outer membrane" EXACT [] +is_a: GO:0031230 ! intrinsic component of cell outer membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031240 ! external side of cell outer membrane +relationship: part_of GO:0031240 ! external side of cell outer membrane + +[Term] +id: GO:0031244 +name: extrinsic component of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "extrinsic to cell outer membrane" NARROW [] +is_a: GO:0019898 ! extrinsic component of membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0009279 ! cell outer membrane +relationship: part_of GO:0009279 ! cell outer membrane + +[Term] +id: GO:0031245 +name: extrinsic component of periplasmic side of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "extrinsic to internal leaflet of cell outer membrane" NARROW [GOC:ab] +synonym: "extrinsic to internal side of cell outer membrane" EXACT [] +synonym: "extrinsic to internal side of outer membrane" EXACT [] +synonym: "extrinsic to periplasmic side of cell outer membrane" EXACT [] +is_a: GO:0031244 ! extrinsic component of cell outer membrane +intersection_of: GO:0031244 ! extrinsic component of cell outer membrane +intersection_of: part_of GO:0031241 ! periplasmic side of cell outer membrane +relationship: part_of GO:0031241 ! periplasmic side of cell outer membrane + +[Term] +id: GO:0031246 +name: intrinsic component of periplasmic side of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor." [GOC:dos, GOC:mah, GOC:mtg_sensu] +synonym: "intrinsic to external side of cell outer membrane" NARROW [] +synonym: "intrinsic to internal leaflet of cell outer membrane" EXACT [GOC:ab] +synonym: "intrinsic to internal side of cell outer membrane" EXACT [] +synonym: "intrinsic to internal side of outer membrane" EXACT [] +is_a: GO:0031230 ! intrinsic component of cell outer membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031241 ! periplasmic side of cell outer membrane +relationship: part_of GO:0031241 ! periplasmic side of cell outer membrane + +[Term] +id: GO:0031247 +name: actin rod assembly +namespace: biological_process +def: "The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules." [GOC:pg, PMID:14706699] +synonym: "actin rod formation" RELATED [GOC:mah] +is_a: GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0031248 +name: protein acetyltransferase complex +namespace: cellular_component +def: "A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule." [GOC:bf] +subset: goslim_pir +is_a: GO:1902493 ! acetyltransferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031249 +name: denatured protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with denatured proteins." [GOC:mlg] +comment: Note that this term should not be confused with 'unfolded protein binding ; GO:0051082', which usually refers to proteins that have not yet folded into their active states. Denatured proteins once were in their correct functional conformations, but have become incorrectly folded, and often form aggregates. +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0031250 +name: anaerobic ribonucleoside-triphosphate reductase complex +namespace: cellular_component +def: "An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit." [GOC:mlg] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031251 +name: PAN complex +namespace: cellular_component +def: "A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces." [PMID:9774670] +synonym: "poly(A) nuclease complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031252 +name: cell leading edge +namespace: cellular_component +def: "The area of a motile cell closest to the direction of movement." [GOC:pg] +subset: goslim_pir +synonym: "front of cell" EXACT [] +synonym: "leading edge of cell" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0031253 +name: cell projection membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah] +synonym: "membrane extension" RELATED [] +synonym: "membrane projection" RELATED [] +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0031254 +name: cell trailing edge +namespace: cellular_component +def: "The area of a motile cell opposite to the direction of movement." [GOC:pg] +subset: goslim_pir +synonym: "back of cell" EXACT [] +synonym: "trailing edge" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0031255 +name: lateral part of motile cell +namespace: cellular_component +def: "The area of a motile cell perpendicular to the direction of movement." [GOC:pg, GOC:pr] +is_a: GO:0097574 ! lateral part of cell + +[Term] +id: GO:0031256 +name: leading edge membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0031257 +name: cell trailing edge membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding the trailing edge of a motile cell." [GOC:mah] +synonym: "trailing edge membrane" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0031254 ! cell trailing edge + +[Term] +id: GO:0031258 +name: lamellipodium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a lamellipodium." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +is_a: GO:0031256 ! leading edge membrane +relationship: part_of GO:0030027 ! lamellipodium + +[Term] +id: GO:0031259 +name: uropod membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a uropod." [GOC:mah] +synonym: "uropodium membrane" EXACT [] +is_a: GO:0031253 ! cell projection membrane +is_a: GO:0031257 ! cell trailing edge membrane +relationship: part_of GO:0001931 ! uropod + +[Term] +id: GO:0031260 +name: pseudopodium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a pseudopodium." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0031143 ! pseudopodium + +[Term] +id: GO:0031261 +name: DNA replication preinitiation complex +namespace: cellular_component +def: "A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present." [GOC:bf, GOC:hjd, GOC:jl, GOC:pr, GOC:rb, GOC:vw, PMID:12694535, PMID:15194812, PMID:17230184] +synonym: "pre-IC" EXACT [] +is_a: GO:0032993 ! protein-DNA complex +relationship: has_part GO:0005656 ! nuclear pre-replicative complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0031262 +name: Ndc80 complex +namespace: cellular_component +def: "An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25." [GOC:krc, GOC:vw, PMID:15509863, PMID:15661517, PMID:28502666] +synonym: "Nuf2-Ndc80 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0031617 ! NMS complex + +[Term] +id: GO:0031263 +name: ATPase-coupled amine transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in)." [GOC:mlg] +synonym: "amine ABC transporter" NARROW [] +synonym: "amine-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent amine transporter activity" EXACT [] +is_a: GO:0005275 ! amine transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0031264 +name: death-inducing signaling complex +namespace: cellular_component +def: "A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10." [GOC:mtg_apoptosis, PMID:12628743, PMID:12655293, PMID:8521815] +comment: Gene products that may be annotated to this term include: 1) ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 2) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. +subset: goslim_pir +synonym: "death receptor-induced signaling complex" EXACT [] +synonym: "death receptor-induced signalling complex" EXACT [] +synonym: "death-inducing signalling complex" EXACT [] +synonym: "DISC" EXACT [] +synonym: "DISC protein complex" EXACT [] +xref: Wikipedia:Death-inducing_signaling_complex +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0031265 +name: CD95 death-inducing signaling complex +namespace: cellular_component +def: "A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293] +synonym: "CD95 death-inducing signalling complex" EXACT [] +synonym: "CD95 DISC" EXACT [] +synonym: "Fas death-inducing signaling complex" EXACT [] +is_a: GO:0031264 ! death-inducing signaling complex + +[Term] +id: GO:0031266 +name: TRAIL death-inducing signaling complex +namespace: cellular_component +def: "A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293] +synonym: "TRAIL death-inducing signalling complex" EXACT [] +synonym: "TRAIL DISC" EXACT [] +is_a: GO:0031264 ! death-inducing signaling complex + +[Term] +id: GO:0031267 +name: small GTPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small monomeric GTPase." [GOC:mah] +is_a: GO:0051020 ! GTPase binding + +[Term] +id: GO:0031268 +name: pseudopodium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement." [GOC:pg] +synonym: "pseudopodium organisation" EXACT [] +synonym: "pseudopodium organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization + +[Term] +id: GO:0031269 +name: pseudopodium assembly +namespace: biological_process +def: "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane." [GOC:dph, GOC:mah, GOC:pg, GOC:tb] +synonym: "pseudopodium extension" EXACT [] +synonym: "pseudopodium formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0031268 ! pseudopodium organization +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0031270 +name: pseudopodium retraction +namespace: biological_process +def: "The myosin-based contraction and retraction of the pseudopodium." [GOC:pg] +is_a: GO:0031268 ! pseudopodium organization + +[Term] +id: GO:0031271 +name: lateral pseudopodium assembly +namespace: biological_process +def: "The extension of a pseudopodium from the lateral area of a cell." [GOC:dph, GOC:mah, GOC:pg, GOC:tb] +synonym: "lateral pseudopodium formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0031269 ! pseudopodium assembly + +[Term] +id: GO:0031272 +name: regulation of pseudopodium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] +synonym: "regulation of pseudopodium formation" RELATED [] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031269 ! pseudopodium assembly +relationship: regulates GO:0031269 ! pseudopodium assembly + +[Term] +id: GO:0031273 +name: negative regulation of pseudopodium assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] +synonym: "down regulation of pseudopodium formation" RELATED [] +synonym: "down-regulation of pseudopodium formation" RELATED [] +synonym: "downregulation of pseudopodium formation" RELATED [] +synonym: "inhibition of pseudopodium formation" NARROW [] +synonym: "negative regulation of pseudopodium formation" RELATED [] +is_a: GO:0031272 ! regulation of pseudopodium assembly +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031269 ! pseudopodium assembly +relationship: negatively_regulates GO:0031269 ! pseudopodium assembly + +[Term] +id: GO:0031274 +name: positive regulation of pseudopodium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] +synonym: "activation of pseudopodium formation" NARROW [] +synonym: "positive regulation of pseudopodium formation" RELATED [GOC:dph] +synonym: "stimulation of pseudopodium formation" NARROW [] +synonym: "up regulation of pseudopodium formation" RELATED [] +synonym: "up-regulation of pseudopodium formation" RELATED [] +synonym: "upregulation of pseudopodium formation" RELATED [] +is_a: GO:0031272 ! regulation of pseudopodium assembly +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031269 ! pseudopodium assembly +relationship: positively_regulates GO:0031269 ! pseudopodium assembly + +[Term] +id: GO:0031275 +name: regulation of lateral pseudopodium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb] +synonym: "regulation of lateral pseudopodium formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031272 ! regulation of pseudopodium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031271 ! lateral pseudopodium assembly +relationship: regulates GO:0031271 ! lateral pseudopodium assembly + +[Term] +id: GO:0031276 +name: negative regulation of lateral pseudopodium assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb] +synonym: "down regulation of lateral pseudopodium formation" RELATED [] +synonym: "down-regulation of lateral pseudopodium formation" RELATED [] +synonym: "downregulation of lateral pseudopodium formation" RELATED [] +synonym: "inhibition of lateral pseudopodium formation" NARROW [] +synonym: "negative regulation of lateral pseudopodium formation" RELATED [GOC:dph] +is_a: GO:0031273 ! negative regulation of pseudopodium assembly +is_a: GO:0031275 ! regulation of lateral pseudopodium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031271 ! lateral pseudopodium assembly +relationship: negatively_regulates GO:0031271 ! lateral pseudopodium assembly + +[Term] +id: GO:0031277 +name: positive regulation of lateral pseudopodium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:dph, GOC:pg, GOC:tb] +synonym: "activation of lateral pseudopodium formation" NARROW [] +synonym: "positive regulation of lateral pseudopodium formation" RELATED [] +synonym: "stimulation of lateral pseudopodium formation" NARROW [] +synonym: "up regulation of lateral pseudopodium formation" RELATED [] +synonym: "up-regulation of lateral pseudopodium formation" RELATED [] +synonym: "upregulation of lateral pseudopodium formation" RELATED [] +is_a: GO:0031274 ! positive regulation of pseudopodium assembly +is_a: GO:0031275 ! regulation of lateral pseudopodium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031271 ! lateral pseudopodium assembly +relationship: positively_regulates GO:0031271 ! lateral pseudopodium assembly + +[Term] +id: GO:0031278 +name: alpha-1,2-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage." [PMID:7522655] +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0031279 +name: regulation of cyclase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclase activity." [GOC:mah] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009975 ! cyclase activity +relationship: regulates GO:0009975 ! cyclase activity + +[Term] +id: GO:0031280 +name: negative regulation of cyclase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of a cyclase." [GOC:mah] +synonym: "down regulation of cyclase activity" EXACT [] +synonym: "down-regulation of cyclase activity" EXACT [] +synonym: "downregulation of cyclase activity" EXACT [] +synonym: "inhibition of cyclase activity" NARROW [] +is_a: GO:0031279 ! regulation of cyclase activity +is_a: GO:0043086 ! negative regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009975 ! cyclase activity +relationship: negatively_regulates GO:0009975 ! cyclase activity + +[Term] +id: GO:0031281 +name: positive regulation of cyclase activity +namespace: biological_process +def: "Any process that activates or increases the activity of a cyclase." [GOC:mah] +synonym: "activation of cyclase activity" NARROW [] +synonym: "stimulation of cyclase activity" NARROW [] +synonym: "up regulation of cyclase activity" EXACT [] +synonym: "up-regulation of cyclase activity" EXACT [] +synonym: "upregulation of cyclase activity" EXACT [] +is_a: GO:0031279 ! regulation of cyclase activity +is_a: GO:0043085 ! positive regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009975 ! cyclase activity +relationship: positively_regulates GO:0009975 ! cyclase activity + +[Term] +id: GO:0031282 +name: regulation of guanylate cyclase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] +is_a: GO:0031279 ! regulation of cyclase activity +is_a: GO:0051339 ! regulation of lyase activity +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004383 ! guanylate cyclase activity +relationship: regulates GO:0004383 ! guanylate cyclase activity + +[Term] +id: GO:0031283 +name: negative regulation of guanylate cyclase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] +synonym: "down regulation of guanylate cyclase activity" EXACT [] +synonym: "down-regulation of guanylate cyclase activity" EXACT [] +synonym: "downregulation of guanylate cyclase activity" EXACT [] +synonym: "inhibition of guanylate cyclase activity" NARROW [] +is_a: GO:0031280 ! negative regulation of cyclase activity +is_a: GO:0031282 ! regulation of guanylate cyclase activity +is_a: GO:0051350 ! negative regulation of lyase activity +is_a: GO:1900372 ! negative regulation of purine nucleotide biosynthetic process +intersection_of: GO:0043086 ! negative regulation of catalytic activity +intersection_of: negatively_regulates GO:0004383 ! guanylate cyclase activity +relationship: negatively_regulates GO:0004383 ! guanylate cyclase activity + +[Term] +id: GO:0031284 +name: positive regulation of guanylate cyclase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] +synonym: "activation of guanylate cyclase activity" NARROW [] +synonym: "stimulation of guanylate cyclase activity" NARROW [] +synonym: "up regulation of guanylate cyclase activity" EXACT [] +synonym: "up-regulation of guanylate cyclase activity" EXACT [] +synonym: "upregulation of guanylate cyclase activity" EXACT [] +is_a: GO:0031281 ! positive regulation of cyclase activity +is_a: GO:0031282 ! regulation of guanylate cyclase activity +is_a: GO:0051349 ! positive regulation of lyase activity +is_a: GO:1900373 ! positive regulation of purine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004383 ! guanylate cyclase activity +relationship: positively_regulates GO:0004383 ! guanylate cyclase activity + +[Term] +id: GO:0031285 +name: regulation of sorocarp stalk cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [GOC:kp, GOC:mtg_sensu, PMID:4338436] +synonym: "regulation of stalk cell differentiation" EXACT [] +is_a: GO:0031156 ! regulation of sorocarp development +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031149 ! sorocarp stalk cell differentiation +relationship: regulates GO:0031149 ! sorocarp stalk cell differentiation + +[Term] +id: GO:0031286 +name: negative regulation of sorocarp stalk cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [GOC:kp, GOC:mtg_sensu, PMID:4338436] +synonym: "down regulation of stalk cell differentiation" EXACT [] +synonym: "down-regulation of stalk cell differentiation" EXACT [] +synonym: "downregulation of stalk cell differentiation" EXACT [] +synonym: "inhibition of stalk cell differentiation" NARROW [] +synonym: "negative regulation of stalk cell differentiation" EXACT [] +is_a: GO:0031285 ! regulation of sorocarp stalk cell differentiation +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031149 ! sorocarp stalk cell differentiation +relationship: negatively_regulates GO:0031149 ! sorocarp stalk cell differentiation + +[Term] +id: GO:0031287 +name: positive regulation of sorocarp stalk cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum." [GOC:kp, GOC:mtg_sensu, PMID:4338436] +synonym: "activation of stalk cell differentiation" NARROW [] +synonym: "positive regulation of stalk cell differentiation" EXACT [] +synonym: "stimulation of stalk cell differentiation" NARROW [] +synonym: "up regulation of stalk cell differentiation" EXACT [] +synonym: "up-regulation of stalk cell differentiation" EXACT [] +synonym: "upregulation of stalk cell differentiation" EXACT [] +is_a: GO:0031285 ! regulation of sorocarp stalk cell differentiation +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031149 ! sorocarp stalk cell differentiation +relationship: positively_regulates GO:0031149 ! sorocarp stalk cell differentiation + +[Term] +id: GO:0031288 +name: sorocarp morphogenesis +namespace: biological_process +def: "The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum." [GOC:kp, GOC:mtg_sensu, PMID:4332228] +synonym: "fruiting body morphogenesis" BROAD [DDANAT:0000012] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0030587 ! sorocarp development + +[Term] +id: GO:0031289 +name: actin phosphorylation +namespace: biological_process +def: "The transfer of one or more phosphate groups to an actin molecule." [GOC:mah] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0030047 ! actin modification + +[Term] +id: GO:0031290 +name: retinal ganglion cell axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:ejs] +synonym: "retinal ganglion cell axon pathfinding" EXACT [] +is_a: GO:0007411 ! axon guidance + +[Term] +id: GO:0031291 +name: Ran protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state." [GOC:mah] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0031292 +name: gene conversion at mating-type locus, DNA double-strand break processing +namespace: biological_process +def: "The 5' to 3' exonucleolytic resection of the DNA at the site of the break at the mating-type locus to form a 3' single-strand DNA overhang." [GOC:mah] +is_a: GO:0000729 ! DNA double-strand break processing +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0000729 ! DNA double-strand break processing +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0031293 +name: membrane protein intracellular domain proteolysis +namespace: biological_process +def: "The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain." [PMID:12808018] +synonym: "membrane protein solubilization" RELATED [] +is_a: GO:0033619 ! membrane protein proteolysis + +[Term] +id: GO:0031294 +name: lymphocyte costimulation +namespace: biological_process +def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation." [ISBN:0781735149] +synonym: "lymphocyte co-stimulation" EXACT [] +is_a: GO:0002376 ! immune system process +is_a: GO:0051251 ! positive regulation of lymphocyte activation + +[Term] +id: GO:0031295 +name: T cell costimulation +namespace: biological_process +def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation." [ISBN:0781735149] +synonym: "T cell co-stimulation" EXACT [] +synonym: "T lymphocyte costimulation" EXACT [] +synonym: "T-cell co-stimulation" EXACT [] +synonym: "T-cell costimulation" EXACT [] +synonym: "T-lymphocyte costimulation" EXACT [] +is_a: GO:0031294 ! lymphocyte costimulation +is_a: GO:0050870 ! positive regulation of T cell activation + +[Term] +id: GO:0031296 +name: B cell costimulation +namespace: biological_process +def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation." [ISBN:0781735149] +synonym: "B cell co-stimulation" EXACT [] +synonym: "B lymphocyte co-stimulation" EXACT [] +synonym: "B lymphocyte costimulation" EXACT [] +synonym: "B-cell co-stimulation" EXACT [] +synonym: "B-cell costimulation" EXACT [] +synonym: "B-lymphocyte co-stimulation" EXACT [] +synonym: "B-lymphocyte costimulation" EXACT [] +is_a: GO:0031294 ! lymphocyte costimulation +is_a: GO:0050871 ! positive regulation of B cell activation + +[Term] +id: GO:0031297 +name: replication fork processing +namespace: biological_process +alt_id: GO:0034065 +def: "The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes." [GOC:vw, PMID:11459955, PMID:15367656, PMID:17660542] +synonym: "collapsed replication fork processing" EXACT [] +synonym: "recovery from replication fork arrest" EXACT [] +synonym: "recovery from replication fork arrest at rDNA locus" NARROW [] +synonym: "recovery from replication fork stalling" EXACT [] +synonym: "recovery from replication fork stalling at rDNA locus" NARROW [] +synonym: "replication fork processing at rDNA locus" NARROW [] +synonym: "replication fork processing at ribosomal DNA locus" NARROW [] +synonym: "replication fork restart" RELATED [PMID:20842177] +synonym: "replication restart" RELATED [GOC:bhm, PMID:15780929] +is_a: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity + +[Term] +id: GO:0031298 +name: replication fork protection complex +namespace: cellular_component +def: "A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling." [PMID:15367656] +synonym: "replisome progression complex" EXACT [GOC:vw] +synonym: "Swi1-Swi3 complex" NARROW [] +synonym: "TIMELESS-TIPIN complex" NARROW [GOC:mah, GOC:vw] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043596 ! nuclear replication fork + +[Term] +id: GO:0031299 +name: taurine-pyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde." [EC:2.6.1.77, RHEA:10420] +synonym: "taurine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.77] +synonym: "Tpa" RELATED [EC:2.6.1.77] +xref: EC:2.6.1.77 +xref: KEGG_REACTION:R05652 +xref: MetaCyc:TAURINE-AMINOTRANSFERASE-RXN +xref: RHEA:10420 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0031300 +name: intrinsic component of organelle membrane +namespace: cellular_component +def: "The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to organelle membrane" NARROW [] +is_a: GO:0031224 ! intrinsic component of membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031090 ! organelle membrane +relationship: part_of GO:0031090 ! organelle membrane + +[Term] +id: GO:0031301 +name: integral component of organelle membrane +namespace: cellular_component +def: "The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to organelle membrane" EXACT [] +is_a: GO:0016021 ! integral component of membrane +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0031090 ! organelle membrane + +[Term] +id: GO:0031302 +name: intrinsic component of endosome membrane +namespace: cellular_component +def: "The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to endosome membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0010008 ! endosome membrane +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0031303 +name: integral component of endosome membrane +namespace: cellular_component +def: "The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to endosome membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0031302 ! intrinsic component of endosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0031304 +name: intrinsic component of mitochondrial inner membrane +namespace: cellular_component +def: "The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to mitochondrial inner membrane" NARROW [] +is_a: GO:0098573 ! intrinsic component of mitochondrial membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005743 ! mitochondrial inner membrane +relationship: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0031305 +name: integral component of mitochondrial inner membrane +namespace: cellular_component +def: "The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to mitochondrial inner membrane" EXACT [] +is_a: GO:0031304 ! intrinsic component of mitochondrial inner membrane +is_a: GO:0032592 ! integral component of mitochondrial membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0031306 +name: intrinsic component of mitochondrial outer membrane +namespace: cellular_component +def: "The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to mitochondrial outer membrane" NARROW [] +is_a: GO:0098573 ! intrinsic component of mitochondrial membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005741 ! mitochondrial outer membrane +relationship: part_of GO:0005741 ! mitochondrial outer membrane + +[Term] +id: GO:0031307 +name: integral component of mitochondrial outer membrane +namespace: cellular_component +def: "The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to mitochondrial outer membrane" NARROW [] +is_a: GO:0031306 ! intrinsic component of mitochondrial outer membrane +is_a: GO:0032592 ! integral component of mitochondrial membrane +intersection_of: GO:0032592 ! integral component of mitochondrial membrane +intersection_of: part_of GO:0005741 ! mitochondrial outer membrane + +[Term] +id: GO:0031308 +name: intrinsic component of nuclear outer membrane +namespace: cellular_component +def: "The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to nuclear outer membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005640 ! nuclear outer membrane +relationship: part_of GO:0005640 ! nuclear outer membrane + +[Term] +id: GO:0031309 +name: integral component of nuclear outer membrane +namespace: cellular_component +def: "The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to nuclear outer membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0031308 ! intrinsic component of nuclear outer membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005640 ! nuclear outer membrane + +[Term] +id: GO:0031310 +name: intrinsic component of vacuolar membrane +namespace: cellular_component +def: "The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to vacuolar membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0005774 ! vacuolar membrane +relationship: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0031311 +name: intrinsic component of contractile vacuolar membrane +namespace: cellular_component +def: "The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to contractile vacuolar membrane" NARROW [] +is_a: GO:0031310 ! intrinsic component of vacuolar membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031164 ! contractile vacuolar membrane +relationship: part_of GO:0031164 ! contractile vacuolar membrane + +[Term] +id: GO:0031312 +name: extrinsic component of organelle membrane +namespace: cellular_component +def: "The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to organelle membrane" NARROW [] +is_a: GO:0019898 ! extrinsic component of membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0031090 ! organelle membrane +relationship: part_of GO:0031090 ! organelle membrane +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0031313 +name: extrinsic component of endosome membrane +namespace: cellular_component +def: "The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to endosome membrane" NARROW [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0010008 ! endosome membrane +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0031314 +name: extrinsic component of mitochondrial inner membrane +namespace: cellular_component +def: "The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to mitochondrial inner membrane" NARROW [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005743 ! mitochondrial inner membrane +relationship: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0031315 +name: extrinsic component of mitochondrial outer membrane +namespace: cellular_component +def: "The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to mitochondrial outer membrane" NARROW [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005741 ! mitochondrial outer membrane +relationship: part_of GO:0005741 ! mitochondrial outer membrane + +[Term] +id: GO:0031316 +name: extrinsic component of nuclear outer membrane +namespace: cellular_component +def: "The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to nuclear outer membrane" NARROW [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005640 ! nuclear outer membrane +relationship: part_of GO:0005640 ! nuclear outer membrane + +[Term] +id: GO:0031317 +name: tripartite ATP-independent periplasmic transporter complex +namespace: cellular_component +def: "A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients." [GOC:mlg] +synonym: "TRAP transporter complex" EXACT [] +synonym: "TRAP-T transporter complex" EXACT [] +is_a: GO:1990351 ! transporter complex + +[Term] +id: GO:0031318 +name: detection of folic acid +namespace: biological_process +def: "The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal." [GOC:pg] +synonym: "detection of folate" EXACT [] +synonym: "folate detection" EXACT [] +synonym: "folate sensing" EXACT [] +synonym: "folic acid detection" EXACT [] +synonym: "folic acid sensing" EXACT [] +is_a: GO:0009594 ! detection of nutrient +is_a: GO:0051593 ! response to folic acid + +[Term] +id: GO:0031319 +name: detection of cAMP +namespace: biological_process +def: "The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP." [GOC:pg] +synonym: "3',5'-cAMP detection" EXACT [] +synonym: "3',5'-cAMP sensing" EXACT [] +synonym: "cAMP detection" EXACT [] +synonym: "cAMP sensing" EXACT [] +synonym: "cyclic AMP detection" EXACT [] +synonym: "detection of 3',5' cAMP" EXACT [] +synonym: "detection of 3',5'-cAMP" EXACT [] +synonym: "detection of adenosine 3',5'-cyclophosphate" EXACT [] +synonym: "detection of cyclic AMP" EXACT [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0051591 ! response to cAMP + +[Term] +id: GO:0031320 +name: hexitol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor." [GOC:mah] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0031321 +name: ascospore-type prospore assembly +namespace: biological_process +def: "During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane." [GOC:mah, PMID:14702385] +synonym: "ascospore-type prospore formation" EXACT [] +synonym: "forespore formation" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0030437 ! ascospore formation + +[Term] +id: GO:0031322 +name: ascospore-type prospore-specific spindle pole body remodeling +namespace: biological_process +def: "A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)." [GOC:mah, PMID:14702385] +synonym: "ascospore-type prospore-specific spindle pole body modification" RELATED [GOC:vw] +synonym: "ascospore-type prospore-specific spindle pole body remodelling" EXACT [GOC:mah] +synonym: "forespore specific spindle pole body remodeling" EXACT [] +synonym: "forespore-specific spindle pole body remodeling" EXACT [] +synonym: "prospore-specific spindle pole body remodeling" EXACT [] +synonym: "sporulation-specific spindle pole body remodeling" EXACT [] +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0000226 ! microtubule cytoskeleton organization +relationship: part_of GO:0031321 ! ascospore-type prospore assembly + +[Term] +id: GO:0031323 +name: regulation of cellular metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] +synonym: "regulation of cellular metabolism" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044237 ! cellular metabolic process +relationship: regulates GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0031324 +name: negative regulation of cellular metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] +synonym: "down regulation of cellular metabolic process" EXACT [] +synonym: "down-regulation of cellular metabolic process" EXACT [] +synonym: "downregulation of cellular metabolic process" EXACT [] +synonym: "inhibition of cellular metabolic process" NARROW [] +synonym: "negative regulation of cellular metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044237 ! cellular metabolic process +relationship: negatively_regulates GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0031325 +name: positive regulation of cellular metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] +synonym: "activation of cellular metabolic process" NARROW [] +synonym: "positive regulation of cellular metabolism" EXACT [] +synonym: "stimulation of cellular metabolic process" NARROW [] +synonym: "up regulation of cellular metabolic process" EXACT [] +synonym: "up-regulation of cellular metabolic process" EXACT [] +synonym: "upregulation of cellular metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044237 ! cellular metabolic process +relationship: positively_regulates GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0031326 +name: regulation of cellular biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] +synonym: "regulation of cellular anabolism" EXACT [] +synonym: "regulation of cellular biosynthesis" EXACT [] +synonym: "regulation of cellular formation" EXACT [] +synonym: "regulation of cellular synthesis" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044249 ! cellular biosynthetic process +relationship: regulates GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0031327 +name: negative regulation of cellular biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] +synonym: "down regulation of cellular biosynthetic process" EXACT [] +synonym: "down-regulation of cellular biosynthetic process" EXACT [] +synonym: "downregulation of cellular biosynthetic process" EXACT [] +synonym: "inhibition of cellular biosynthetic process" NARROW [] +synonym: "negative regulation of cellular anabolism" EXACT [] +synonym: "negative regulation of cellular biosynthesis" EXACT [] +synonym: "negative regulation of cellular formation" EXACT [] +synonym: "negative regulation of cellular synthesis" EXACT [] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044249 ! cellular biosynthetic process +relationship: negatively_regulates GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0031328 +name: positive regulation of cellular biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] +synonym: "activation of cellular biosynthetic process" NARROW [] +synonym: "positive regulation of cellular anabolism" EXACT [] +synonym: "positive regulation of cellular biosynthesis" EXACT [] +synonym: "positive regulation of cellular formation" EXACT [] +synonym: "positive regulation of cellular synthesis" EXACT [] +synonym: "stimulation of cellular biosynthetic process" NARROW [] +synonym: "up regulation of cellular biosynthetic process" EXACT [] +synonym: "up-regulation of cellular biosynthetic process" EXACT [] +synonym: "upregulation of cellular biosynthetic process" EXACT [] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044249 ! cellular biosynthetic process +relationship: positively_regulates GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0031329 +name: regulation of cellular catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] +synonym: "regulation of cellular breakdown" EXACT [] +synonym: "regulation of cellular catabolism" EXACT [] +synonym: "regulation of cellular degradation" EXACT [] +is_a: GO:0009894 ! regulation of catabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044248 ! cellular catabolic process +relationship: regulates GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0031330 +name: negative regulation of cellular catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] +synonym: "down regulation of cellular catabolic process" EXACT [] +synonym: "down-regulation of cellular catabolic process" EXACT [] +synonym: "downregulation of cellular catabolic process" EXACT [] +synonym: "inhibition of cellular catabolic process" NARROW [] +synonym: "negative regulation of cellular breakdown" EXACT [] +synonym: "negative regulation of cellular catabolism" EXACT [] +synonym: "negative regulation of cellular degradation" EXACT [] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044248 ! cellular catabolic process +relationship: negatively_regulates GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0031331 +name: positive regulation of cellular catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] +synonym: "activation of cellular catabolic process" NARROW [] +synonym: "positive regulation of cellular breakdown" EXACT [] +synonym: "positive regulation of cellular catabolism" EXACT [] +synonym: "positive regulation of cellular degradation" EXACT [] +synonym: "stimulation of cellular catabolic process" NARROW [] +synonym: "up regulation of cellular catabolic process" EXACT [] +synonym: "up-regulation of cellular catabolic process" EXACT [] +synonym: "upregulation of cellular catabolic process" EXACT [] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044248 ! cellular catabolic process +relationship: positively_regulates GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0031332 +name: RNAi effector complex +namespace: cellular_component +def: "Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins." [GOC:mah, PMID:14704433] +subset: goslim_pir +is_a: GO:1990904 ! ribonucleoprotein complex + +[Term] +id: GO:0031333 +name: negative regulation of protein-containing complex assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] +synonym: "down regulation of protein complex assembly" EXACT [] +synonym: "down-regulation of protein complex assembly" EXACT [] +synonym: "downregulation of protein complex assembly" EXACT [] +synonym: "inhibition of protein complex assembly" NARROW [] +synonym: "negative regulation of protein complex assembly" RELATED [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0065003 ! protein-containing complex assembly +relationship: negatively_regulates GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0031334 +name: positive regulation of protein-containing complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] +synonym: "activation of protein complex assembly" NARROW [] +synonym: "positive regulation of protein complex assembly" RELATED [] +synonym: "stimulation of protein complex assembly" NARROW [] +synonym: "up regulation of protein complex assembly" EXACT [] +synonym: "up-regulation of protein complex assembly" EXACT [] +synonym: "upregulation of protein complex assembly" EXACT [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0065003 ! protein-containing complex assembly +relationship: positively_regulates GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0031335 +name: regulation of sulfur amino acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] +synonym: "regulation of sulfur amino acid metabolism" EXACT [] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000096 ! sulfur amino acid metabolic process +relationship: regulates GO:0000096 ! sulfur amino acid metabolic process + +[Term] +id: GO:0031336 +name: negative regulation of sulfur amino acid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] +synonym: "down regulation of sulfur amino acid metabolic process" EXACT [] +synonym: "down-regulation of sulfur amino acid metabolic process" EXACT [] +synonym: "downregulation of sulfur amino acid metabolic process" EXACT [] +synonym: "inhibition of sulfur amino acid metabolic process" NARROW [] +synonym: "negative regulation of sulfur amino acid metabolism" EXACT [] +is_a: GO:0031335 ! regulation of sulfur amino acid metabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000096 ! sulfur amino acid metabolic process +relationship: negatively_regulates GO:0000096 ! sulfur amino acid metabolic process + +[Term] +id: GO:0031337 +name: positive regulation of sulfur amino acid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] +synonym: "activation of sulfur amino acid metabolic process" NARROW [] +synonym: "positive regulation of sulfur amino acid metabolism" EXACT [] +synonym: "stimulation of sulfur amino acid metabolic process" NARROW [] +synonym: "up regulation of sulfur amino acid metabolic process" EXACT [] +synonym: "up-regulation of sulfur amino acid metabolic process" EXACT [] +synonym: "upregulation of sulfur amino acid metabolic process" EXACT [] +is_a: GO:0031335 ! regulation of sulfur amino acid metabolic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000096 ! sulfur amino acid metabolic process +relationship: positively_regulates GO:0000096 ! sulfur amino acid metabolic process + +[Term] +id: GO:0031338 +name: regulation of vesicle fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006906 ! vesicle fusion +relationship: regulates GO:0006906 ! vesicle fusion + +[Term] +id: GO:0031339 +name: negative regulation of vesicle fusion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] +synonym: "down regulation of vesicle fusion" EXACT [] +synonym: "down-regulation of vesicle fusion" EXACT [] +synonym: "downregulation of vesicle fusion" EXACT [] +synonym: "inhibition of vesicle fusion" NARROW [] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0031338 ! regulation of vesicle fusion +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006906 ! vesicle fusion +relationship: negatively_regulates GO:0006906 ! vesicle fusion + +[Term] +id: GO:0031340 +name: positive regulation of vesicle fusion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] +synonym: "activation of vesicle fusion" NARROW [] +synonym: "stimulation of vesicle fusion" NARROW [] +synonym: "up regulation of vesicle fusion" EXACT [] +synonym: "up-regulation of vesicle fusion" EXACT [] +synonym: "upregulation of vesicle fusion" EXACT [] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0031338 ! regulation of vesicle fusion +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006906 ! vesicle fusion +relationship: positively_regulates GO:0006906 ! vesicle fusion + +[Term] +id: GO:0031341 +name: regulation of cell killing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism." [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001906 ! cell killing +relationship: regulates GO:0001906 ! cell killing + +[Term] +id: GO:0031342 +name: negative regulation of cell killing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing." [GOC:mah] +synonym: "down regulation of cell killing" EXACT [] +synonym: "down-regulation of cell killing" EXACT [] +synonym: "downregulation of cell killing" EXACT [] +synonym: "inhibition of cell killing" NARROW [] +is_a: GO:0031341 ! regulation of cell killing +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001906 ! cell killing +relationship: negatively_regulates GO:0001906 ! cell killing + +[Term] +id: GO:0031343 +name: positive regulation of cell killing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell killing." [GOC:mah] +synonym: "activation of cell killing" NARROW [] +synonym: "stimulation of cell killing" NARROW [] +synonym: "up regulation of cell killing" EXACT [] +synonym: "up-regulation of cell killing" EXACT [] +synonym: "upregulation of cell killing" EXACT [] +is_a: GO:0031341 ! regulation of cell killing +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001906 ! cell killing +relationship: positively_regulates GO:0001906 ! cell killing + +[Term] +id: GO:0031344 +name: regulation of cell projection organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] +synonym: "regulation of cell projection organisation" EXACT [] +synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030030 ! cell projection organization +relationship: regulates GO:0030030 ! cell projection organization + +[Term] +id: GO:0031345 +name: negative regulation of cell projection organization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] +synonym: "down regulation of cell projection organization" EXACT [GOC:mah] +synonym: "down-regulation of cell projection organization" EXACT [] +synonym: "downregulation of cell projection organization" EXACT [] +synonym: "inhibition of cell projection organization" NARROW [] +synonym: "negative regulation of cell projection organisation" EXACT [] +synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0031344 ! regulation of cell projection organization +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030030 ! cell projection organization +relationship: negatively_regulates GO:0030030 ! cell projection organization + +[Term] +id: GO:0031346 +name: positive regulation of cell projection organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] +synonym: "activation of cell projection organization" NARROW [] +synonym: "positive regulation of cell projection organisation" EXACT [] +synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah] +synonym: "stimulation of cell projection organization" NARROW [] +synonym: "up regulation of cell projection organization" EXACT [] +synonym: "up-regulation of cell projection organization" EXACT [] +synonym: "upregulation of cell projection organization" EXACT [] +is_a: GO:0031344 ! regulation of cell projection organization +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030030 ! cell projection organization +relationship: positively_regulates GO:0030030 ! cell projection organization + +[Term] +id: GO:0031347 +name: regulation of defense response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006952 ! defense response +relationship: regulates GO:0006952 ! defense response + +[Term] +id: GO:0031348 +name: negative regulation of defense response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah] +synonym: "down regulation of defense response" EXACT [] +synonym: "down-regulation of defense response" EXACT [] +synonym: "downregulation of defense response" EXACT [] +synonym: "inhibition of defense response" NARROW [] +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006952 ! defense response +relationship: negatively_regulates GO:0006952 ! defense response + +[Term] +id: GO:0031349 +name: positive regulation of defense response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] +synonym: "activation of defense response" NARROW [] +synonym: "stimulation of defense response" NARROW [] +synonym: "up regulation of defense response" EXACT [] +synonym: "up-regulation of defense response" EXACT [] +synonym: "upregulation of defense response" EXACT [] +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006952 ! defense response +relationship: positively_regulates GO:0006952 ! defense response + +[Term] +id: GO:0031350 +name: intrinsic component of plastid membrane +namespace: cellular_component +def: "The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to plastid membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0042170 ! plastid membrane +relationship: part_of GO:0042170 ! plastid membrane + +[Term] +id: GO:0031351 +name: integral component of plastid membrane +namespace: cellular_component +def: "The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to plastid membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0031350 ! intrinsic component of plastid membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0042170 ! plastid membrane + +[Term] +id: GO:0031352 +name: intrinsic component of plastid inner membrane +namespace: cellular_component +def: "The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to plastid inner membrane" NARROW [] +is_a: GO:0031350 ! intrinsic component of plastid membrane +intersection_of: GO:0031350 ! intrinsic component of plastid membrane +intersection_of: part_of GO:0009528 ! plastid inner membrane +relationship: part_of GO:0009528 ! plastid inner membrane + +[Term] +id: GO:0031353 +name: integral component of plastid inner membrane +namespace: cellular_component +def: "The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to plastid inner membrane" NARROW [] +is_a: GO:0031351 ! integral component of plastid membrane +is_a: GO:0031352 ! intrinsic component of plastid inner membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009528 ! plastid inner membrane + +[Term] +id: GO:0031354 +name: intrinsic component of plastid outer membrane +namespace: cellular_component +def: "The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to plastid outer membrane" NARROW [] +is_a: GO:0031350 ! intrinsic component of plastid membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0009527 ! plastid outer membrane +relationship: part_of GO:0009527 ! plastid outer membrane + +[Term] +id: GO:0031355 +name: integral component of plastid outer membrane +namespace: cellular_component +def: "The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to plastid outer membrane" NARROW [] +is_a: GO:0031351 ! integral component of plastid membrane +is_a: GO:0031354 ! intrinsic component of plastid outer membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009527 ! plastid outer membrane + +[Term] +id: GO:0031356 +name: intrinsic component of chloroplast inner membrane +namespace: cellular_component +def: "The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to chloroplast inner membrane" NARROW [] +is_a: GO:0031352 ! intrinsic component of plastid inner membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0009706 ! chloroplast inner membrane +relationship: part_of GO:0009706 ! chloroplast inner membrane + +[Term] +id: GO:0031357 +name: integral component of chloroplast inner membrane +namespace: cellular_component +def: "The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to chloroplast inner membrane" NARROW [] +is_a: GO:0031353 ! integral component of plastid inner membrane +is_a: GO:0031356 ! intrinsic component of chloroplast inner membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009706 ! chloroplast inner membrane + +[Term] +id: GO:0031358 +name: intrinsic component of chloroplast outer membrane +namespace: cellular_component +def: "The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to chloroplast outer membrane" NARROW [] +is_a: GO:0031354 ! intrinsic component of plastid outer membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0009707 ! chloroplast outer membrane +relationship: part_of GO:0009707 ! chloroplast outer membrane + +[Term] +id: GO:0031359 +name: integral component of chloroplast outer membrane +namespace: cellular_component +def: "The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to chloroplast outer membrane" NARROW [] +is_a: GO:0031355 ! integral component of plastid outer membrane +is_a: GO:0031358 ! intrinsic component of chloroplast outer membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009707 ! chloroplast outer membrane + +[Term] +id: GO:0031360 +name: intrinsic component of thylakoid membrane +namespace: cellular_component +def: "The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to thylakoid membrane" NARROW [] +is_a: GO:0031224 ! intrinsic component of membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0042651 ! thylakoid membrane +relationship: part_of GO:0042651 ! thylakoid membrane + +[Term] +id: GO:0031361 +name: integral component of thylakoid membrane +namespace: cellular_component +def: "The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to thylakoid membrane" NARROW [] +is_a: GO:0016021 ! integral component of membrane +is_a: GO:0031360 ! intrinsic component of thylakoid membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0042651 ! thylakoid membrane + +[Term] +id: GO:0031362 +name: anchored component of external side of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:mah] +synonym: "anchored to external leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "anchored to external side of plasma membrane" EXACT [] +is_a: GO:0031233 ! intrinsic component of external side of plasma membrane +is_a: GO:0046658 ! anchored component of plasma membrane +intersection_of: GO:0046658 ! anchored component of plasma membrane +intersection_of: part_of GO:0009897 ! external side of plasma membrane + +[Term] +id: GO:0031363 +name: N-terminal protein amino acid deamination +namespace: biological_process +def: "The removal of an amino group from the N-terminal amino acid residue of a protein." [GOC:mah] +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0031364 +name: N-terminal protein amino acid deamination, from side chain +namespace: biological_process +def: "The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein." [GOC:mah] +is_a: GO:0031363 ! N-terminal protein amino acid deamination + +[Term] +id: GO:0031365 +name: N-terminal protein amino acid modification +namespace: biological_process +alt_id: GO:0018409 +def: "The alteration of the N-terminal amino acid residue in a protein." [GOC:mah] +synonym: "peptide or protein amino-terminal blocking" RELATED [] +synonym: "peptide/protein amino-terminal blocking" RELATED [] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0031366 +name: N-terminal peptidyl-asparagine deamination +namespace: biological_process +def: "The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein." [GOC:bf, GOC:mah] +is_a: GO:0031364 ! N-terminal protein amino acid deamination, from side chain + +[Term] +id: GO:0031367 +name: N-terminal peptidyl-glutamine deamination +namespace: biological_process +def: "The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein." [GOC:mah] +is_a: GO:0031364 ! N-terminal protein amino acid deamination, from side chain + +[Term] +id: GO:0031368 +name: obsolete Pro-X metallocarboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid." [EC:3.4.17.16, GOC:mah] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase P activity" NARROW [EC:3.4.17.16] +synonym: "membrane Pro-X carboxypeptidase activity" NARROW [EC:3.4.17.16] +synonym: "membrane Pro-Xaa carboxypeptidase" NARROW [] +synonym: "microsomal carboxypeptidase activity" NARROW [EC:3.4.17.16] +synonym: "Pro-X metallocarboxypeptidase activity" EXACT [] +xref: EC:3.4.17.16 +is_obsolete: true +consider: GO:0004181 +consider: GO:0008233 + +[Term] +id: GO:0031369 +name: translation initiation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0031370 +name: eukaryotic initiation factor 4G binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah] +synonym: "eIF4G binding" EXACT [] +is_a: GO:0031369 ! translation initiation factor binding + +[Term] +id: GO:0031371 +name: ubiquitin conjugating enzyme complex +namespace: cellular_component +def: "Any complex that possesses ubiquitin conjugating enzyme activity." [GOC:mah] +subset: goslim_pir +synonym: "E2 complex" RELATED [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031372 +name: UBC13-MMS2 complex +namespace: cellular_component +def: "A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p." [GOC:mah, PMID:15772086] +is_a: GO:0031371 ! ubiquitin conjugating enzyme complex + +[Term] +id: GO:0031375 +name: obsolete type II fatty acid synthase complex +namespace: cellular_component +def: "OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385] +comment: Type II refers to the type of fatty acid synthase. Type I is in a complex, type II is not. +synonym: "type II FAS" EXACT [] +synonym: "type II FAS complex" EXACT [] +synonym: "type II fatty acid synthase" EXACT [] +synonym: "type II fatty acid synthase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031376 +name: obsolete cytosolic type II fatty acid synthase complex +namespace: cellular_component +def: "OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385] +synonym: "cytosolic type II FAS complex" EXACT [] +synonym: "cytosolic type II fatty acid synthase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031377 +name: obsolete mitochondrial type II fatty acid synthase complex +namespace: cellular_component +def: "OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385] +comment: Obsoleted because type II fatty acid synthases are not complexes +synonym: "mitochondrial type II FAS complex" EXACT [] +synonym: "mitochondrial type II fatty acid synthase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031378 +name: obsolete plastid type II fatty acid synthase complex +namespace: cellular_component +def: "OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid." [GOC:mah, ISBN:0471331309, ISBN:0716720094, PMID:12957385] +comment: Obsoleted because type II fatty acid synthase is not a complex. +synonym: "plastid type II FAS complex" EXACT [] +synonym: "plastid type II fatty acid synthase complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031379 +name: RNA-directed RNA polymerase complex +namespace: cellular_component +def: "A protein complex that possesses RNA-directed RNA polymerase activity." [GOC:mah] +is_a: GO:0030880 ! RNA polymerase complex + +[Term] +id: GO:0031380 +name: nuclear RNA-directed RNA polymerase complex +namespace: cellular_component +def: "A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain." [GOC:vw, PMID:15607976] +synonym: "Rdr1 complex" NARROW [] +synonym: "RDRC" EXACT [] +is_a: GO:0031379 ! RNA-directed RNA polymerase complex +intersection_of: GO:0031379 ! RNA-directed RNA polymerase complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031381 +name: viral RNA-directed RNA polymerase complex +namespace: cellular_component +def: "A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus." [GOC:mah, PMID:15574411, PMID:15613301] +is_a: GO:0031379 ! RNA-directed RNA polymerase complex + +[Term] +id: GO:0031382 +name: mating projection formation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi." [GOC:mah, PMID:14734532] +synonym: "mating projection assembly" EXACT [] +synonym: "mating projection biogenesis" RELATED [GOC:mah] +synonym: "shmooing" NARROW [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: part_of GO:0000753 ! cell morphogenesis involved in conjugation with cellular fusion + +[Term] +id: GO:0031383 +name: regulation of mating projection assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi." [PMID:14734532] +synonym: "regulation of mating projection biogenesis" RELATED [GOC:mah] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +is_a: GO:1905708 ! regulation of cell morphogenesis involved in conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031382 ! mating projection formation +relationship: regulates GO:0031382 ! mating projection formation + +[Term] +id: GO:0031384 +name: regulation of initiation of mating projection growth +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi." [PMID:14734532] +is_a: GO:0031383 ! regulation of mating projection assembly + +[Term] +id: GO:0031385 +name: regulation of termination of mating projection growth +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi." [PMID:14734532] +is_a: GO:0031383 ! regulation of mating projection assembly + +[Term] +id: GO:0031386 +name: protein tag +namespace: molecular_function +def: "A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation." [GOC:dos, GOC:go_curators, PMID:19028679, PMID:20054389, PMID:6305978] +comment: Use this term to annotate conjugated tags, not for conjugating enzymes. At the time of writing, all known gene products with this activity are ubiquitin-like, either based on overall sequence similarity or the presence of common motifs and structures. +subset: goslim_pir +synonym: "covalent modifier" RELATED [GOC:vw] +synonym: "protein tagging activity" RELATED [] +synonym: "ubiquitin" RELATED [] +synonym: "ubiquitin-like protein modifier" EXACT [] +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0031387 +name: MPF complex +namespace: cellular_component +def: "A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC)." [PMID:12045216] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex + +[Term] +id: GO:0031388 +name: organic acid phosphorylation +namespace: biological_process +def: "The process of introducing one or more phosphate groups into an organic acid." [GOC:mah] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0016310 ! phosphorylation + +[Term] +id: GO:0031389 +name: Rad17 RFC-like complex +namespace: cellular_component +def: "A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842] +synonym: "Rad17-RFC" EXACT [] +synonym: "Rad17-RLC" EXACT [] +synonym: "Rad24p RFC-like complex" EXACT [] +synonym: "RFC (Rad17)" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0031390 +name: Ctf18 RFC-like complex +namespace: cellular_component +def: "A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p." [PMID:14614842] +synonym: "Ctf18-RFC" EXACT [] +synonym: "Ctf18-RLC" EXACT [] +synonym: "RFC (Ctf18)" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0031391 +name: Elg1 RFC-like complex +namespace: cellular_component +def: "A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842, PMID:23499004, PMID:27664980] +synonym: "Elg1-RFC" EXACT [] +synonym: "Elg1-RLC" EXACT [] +synonym: "RFC (Elg1)" EXACT [] +is_a: GO:1904949 ! ATPase complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0031392 +name: regulation of prostaglandin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] +synonym: "regulation of prostaglandin anabolism" EXACT [] +synonym: "regulation of prostaglandin biosynthesis" EXACT [] +synonym: "regulation of prostaglandin formation" EXACT [] +synonym: "regulation of prostaglandin synthesis" EXACT [] +is_a: GO:2001279 ! regulation of unsaturated fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001516 ! prostaglandin biosynthetic process +relationship: regulates GO:0001516 ! prostaglandin biosynthetic process + +[Term] +id: GO:0031393 +name: negative regulation of prostaglandin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] +synonym: "down regulation of prostaglandin biosynthetic process" EXACT [] +synonym: "down-regulation of prostaglandin biosynthetic process" EXACT [] +synonym: "downregulation of prostaglandin biosynthetic process" EXACT [] +synonym: "inhibition of prostaglandin biosynthetic process" NARROW [] +synonym: "negative regulation of prostaglandin anabolism" EXACT [] +synonym: "negative regulation of prostaglandin biosynthesis" EXACT [] +synonym: "negative regulation of prostaglandin formation" EXACT [] +synonym: "negative regulation of prostaglandin synthesis" EXACT [] +is_a: GO:0031392 ! regulation of prostaglandin biosynthetic process +is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001516 ! prostaglandin biosynthetic process +relationship: negatively_regulates GO:0001516 ! prostaglandin biosynthetic process + +[Term] +id: GO:0031394 +name: positive regulation of prostaglandin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] +synonym: "activation of prostaglandin biosynthetic process" NARROW [] +synonym: "positive regulation of prostaglandin anabolism" EXACT [] +synonym: "positive regulation of prostaglandin biosynthesis" EXACT [] +synonym: "positive regulation of prostaglandin formation" EXACT [] +synonym: "positive regulation of prostaglandin synthesis" EXACT [] +synonym: "stimulation of prostaglandin biosynthetic process" NARROW [] +synonym: "up regulation of prostaglandin biosynthetic process" EXACT [] +synonym: "up-regulation of prostaglandin biosynthetic process" EXACT [] +synonym: "upregulation of prostaglandin biosynthetic process" EXACT [] +is_a: GO:0031392 ! regulation of prostaglandin biosynthetic process +is_a: GO:2001280 ! positive regulation of unsaturated fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001516 ! prostaglandin biosynthetic process +relationship: positively_regulates GO:0001516 ! prostaglandin biosynthetic process + +[Term] +id: GO:0031395 +name: bursicon neuropeptide hormone complex +namespace: cellular_component +def: "A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits." [GOC:rc] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0031396 +name: regulation of protein ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah] +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016567 ! protein ubiquitination +relationship: regulates GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0031397 +name: negative regulation of protein ubiquitination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah] +synonym: "down regulation of protein ubiquitination" EXACT [] +synonym: "down-regulation of protein ubiquitination" EXACT [] +synonym: "downregulation of protein ubiquitination" EXACT [] +synonym: "inhibition of protein ubiquitination" NARROW [] +is_a: GO:0031396 ! regulation of protein ubiquitination +is_a: GO:1903321 ! negative regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016567 ! protein ubiquitination +relationship: negatively_regulates GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0031398 +name: positive regulation of protein ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein." [GOC:mah] +synonym: "activation of protein ubiquitination" NARROW [] +synonym: "stimulation of protein ubiquitination" NARROW [] +synonym: "up regulation of protein ubiquitination" EXACT [] +synonym: "up-regulation of protein ubiquitination" EXACT [] +synonym: "upregulation of protein ubiquitination" EXACT [] +is_a: GO:0031396 ! regulation of protein ubiquitination +is_a: GO:1903322 ! positive regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016567 ! protein ubiquitination +relationship: positively_regulates GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0031399 +name: regulation of protein modification process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] +subset: goslim_yeast +is_a: GO:0032268 ! regulation of cellular protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006464 ! cellular protein modification process +relationship: regulates GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0031400 +name: negative regulation of protein modification process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] +synonym: "down regulation of protein modification" EXACT [] +synonym: "down-regulation of protein modification" EXACT [] +synonym: "downregulation of protein modification" EXACT [] +synonym: "inhibition of protein modification" NARROW [] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:0032269 ! negative regulation of cellular protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006464 ! cellular protein modification process +relationship: negatively_regulates GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0031401 +name: positive regulation of protein modification process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] +synonym: "activation of protein modification" NARROW [] +synonym: "stimulation of protein modification" NARROW [] +synonym: "up regulation of protein modification" EXACT [] +synonym: "up-regulation of protein modification" EXACT [] +synonym: "upregulation of protein modification" EXACT [] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:0032270 ! positive regulation of cellular protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006464 ! cellular protein modification process +relationship: positively_regulates GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0031402 +name: sodium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sodium ions (Na+)." [GOC:mah] +is_a: GO:0031420 ! alkali metal ion binding + +[Term] +id: GO:0031403 +name: lithium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lithium ions (Li+)." [GOC:mah] +is_a: GO:0031420 ! alkali metal ion binding + +[Term] +id: GO:0031404 +name: chloride ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chloride ions (Cl-)." [GOC:mah] +synonym: "chloride binding" EXACT [] +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0031405 +name: lipoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid." [GOC:mah, ISBN:0198506732] +is_a: GO:0005504 ! fatty acid binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0031406 +name: carboxylic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:mah, ISBN:0198506732] +subset: goslim_pir +is_a: GO:0043168 ! anion binding +is_a: GO:0043177 ! organic acid binding + +[Term] +id: GO:0031407 +name: oxylipin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids." [GOC:mah, PMID:11960741] +synonym: "oxylipin metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0031408 +name: oxylipin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids." [GOC:mah, PMID:11960741] +synonym: "oxylipin anabolism" EXACT [] +synonym: "oxylipin biosynthesis" EXACT [] +synonym: "oxylipin formation" EXACT [] +synonym: "oxylipin synthesis" EXACT [] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0031407 ! oxylipin metabolic process + +[Term] +id: GO:0031409 +name: pigment binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin." [GOC:mah] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0031410 +name: cytoplasmic vesicle +namespace: cellular_component +alt_id: GO:0016023 +def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_mouse +subset: goslim_yeast +synonym: "cytoplasmic membrane bounded vesicle" RELATED [] +synonym: "cytoplasmic membrane-enclosed vesicle" RELATED [] +synonym: "cytoplasmic, membrane-bounded vesicle" RELATED [] +xref: NIF_Subcellular:sao180601769 +is_a: GO:0097708 ! intracellular vesicle +intersection_of: GO:0031982 ! vesicle +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031411 +name: gas vesicle +namespace: cellular_component +def: "An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations." [PMID:22147705, PMID:8177173] +comment: Note that although this organelle is commonly referred to as a 'vesicle' or 'vacuole' in the literature, it is not surrounded by a membrane. +synonym: "gas vacuole" RELATED [GOC:pr] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0031412 +name: gas vesicle organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps." [GOC:mah] +comment: Note that although gas vesicles are commonly referred to as 'vesicles' or 'vacuoles' in the literature, they are not surrounded by a membrane. +synonym: "gas vesicle biosynthesis" NARROW [GOC:mah] +synonym: "gas vesicle formation" NARROW [GOC:mah] +synonym: "gas vesicle organisation" EXACT [] +synonym: "gas vesicle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0031413 +name: regulation of buoyancy +namespace: biological_process +def: "Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases." [GOC:mah, PATO:0001420] +synonym: "buoyancy regulation" EXACT [] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0031414 +name: N-terminal protein acetyltransferase complex +namespace: cellular_component +def: "A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule." [GOC:mah] +synonym: "NAT complex" EXACT [] +is_a: GO:0031248 ! protein acetyltransferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031415 +name: NatA complex +namespace: cellular_component +def: "A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins." [PMID:12890471] +synonym: "N-terminal acetyltransferase A complex" EXACT [] +is_a: GO:0031414 ! N-terminal protein acetyltransferase complex + +[Term] +id: GO:0031416 +name: NatB complex +namespace: cellular_component +def: "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p." [PMID:12890471] +synonym: "N-terminal acetyltransferase B complex" EXACT [] +is_a: GO:0031414 ! N-terminal protein acetyltransferase complex + +[Term] +id: GO:0031417 +name: NatC complex +namespace: cellular_component +def: "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p." [PMID:12890471] +synonym: "N-terminal acetyltransferase C complex" EXACT [] +is_a: GO:0031414 ! N-terminal protein acetyltransferase complex + +[Term] +id: GO:0031418 +name: L-ascorbic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species." [GOC:mah] +synonym: "L-ascorbate binding" EXACT [] +synonym: "vitamin C binding" EXACT [] +is_a: GO:0019842 ! vitamin binding +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0048029 ! monosaccharide binding +is_a: GO:0050662 ! coenzyme binding + +[Term] +id: GO:0031419 +name: cobalamin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:mah] +synonym: "vitamin B12 binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0046906 ! tetrapyrrole binding +is_a: GO:0048037 ! cofactor binding + +[Term] +id: GO:0031420 +name: alkali metal ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen." [GOC:mah] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0031421 +name: invertasome +namespace: cellular_component +def: "A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts." [PMID:11114897, PMID:9732277] +is_a: GO:0032993 ! protein-DNA complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031422 +name: RecQ family helicase-topoisomerase III complex +namespace: cellular_component +def: "A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human." [GOC:bhm, GOC:krc, PMID:15889139] +synonym: "RecQ helicase-Topo III complex" EXACT [PMID:15889139] +synonym: "Sgs1-Top3 complex" NARROW [PMID:15889139] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0031423 +name: hexon binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a hexon, the major protein component of the icosahedral capsid of an adenovirus." [GOC:mah, PMID:12915569] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031424 +name: keratinization +namespace: biological_process +def: "The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns." [GOC:dph, GOC:ebc, GOC:sdb_2009, GOC:tb] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0030216 ! keratinocyte differentiation + +[Term] +id: GO:0031425 +name: chloroplast RNA processing +namespace: biological_process +def: "The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules." [GOC:mah] +is_a: GO:0006396 ! RNA processing +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0031426 +name: polycistronic mRNA processing +namespace: biological_process +def: "The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules." [GOC:mah] +is_a: GO:0006397 ! mRNA processing + +[Term] +id: GO:0031427 +name: response to methotrexate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase." [GOC:ef, GOC:mah, ISBN:0198506732] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0031428 +name: box C/D snoRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs." [ISBN:0879695897, PMID:17284456] +synonym: "box C/D small nucleolar ribonucleoprotein complex" EXACT [GOC:cjm] +synonym: "box C/D snoRNP ribose 2'-O methylase complex" EXACT [PMID:17284456] +synonym: "box C/D snoRNP ribose-2'-O-methyltransferase complex" EXACT [PMID:17284456] +is_a: GO:0005732 ! small nucleolar ribonucleoprotein complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0031429 +name: box H/ACA snoRNP complex +namespace: cellular_component +def: "A box H/ACA RNP complex that is located in the nucleolus." [GOC:vw, ISBN:0879695897, PMID:17284456, PMID:20227365] +synonym: "box H/ACA small nucleolar ribonucleoprotein complex" EXACT [GOC:cjm] +synonym: "box H/ACA snoRNP pseudouridylase complex" EXACT [GOC:mah, GOC:vw, PMID:17284456] +is_a: GO:0072588 ! box H/ACA RNP complex +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0031430 +name: M band +namespace: cellular_component +def: "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." [GOC:mtg_muscle, ISBN:0198506732, ISBN:0815316194] +synonym: "M disc" EXACT [] +synonym: "M line" NARROW [] +synonym: "mesophragma" EXACT [] +synonym: "midline" BROAD [] +xref: Wikipedia:Sarcomere#bands +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031672 ! A band + +[Term] +id: GO:0031431 +name: Dbf4-dependent protein kinase complex +namespace: cellular_component +def: "A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins." [PMID:12045100] +synonym: "Cdc7-Dbf4 complex" NARROW [] +synonym: "DDK" EXACT [] +synonym: "Hsk1-Dfp1 kinase complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031432 +name: titin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively." [GOC:mah, PMID:10481174] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0031433 +name: telethonin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase." [GOC:mah, PMID:10481174] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0031434 +name: mitogen-activated protein kinase kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase." [GOC:mah] +synonym: "MAPKK binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0031435 +name: mitogen-activated protein kinase kinase kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase." [GOC:bf] +synonym: "MAPKKK binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0031436 +name: BRCA1-BARD1 complex +namespace: cellular_component +def: "A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage." [PMID:12787778] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex + +[Term] +id: GO:0031437 +name: regulation of mRNA cleavage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner." [GOC:mah] +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006379 ! mRNA cleavage +relationship: regulates GO:0006379 ! mRNA cleavage + +[Term] +id: GO:0031438 +name: negative regulation of mRNA cleavage +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage." [GOC:mah] +synonym: "down regulation of mRNA cleavage" EXACT [] +synonym: "down-regulation of mRNA cleavage" EXACT [] +synonym: "downregulation of mRNA cleavage" EXACT [] +synonym: "inhibition of mRNA cleavage" NARROW [] +is_a: GO:0031437 ! regulation of mRNA cleavage +is_a: GO:1903312 ! negative regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006379 ! mRNA cleavage +relationship: negatively_regulates GO:0006379 ! mRNA cleavage + +[Term] +id: GO:0031439 +name: positive regulation of mRNA cleavage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA cleavage." [GOC:mah] +synonym: "activation of mRNA cleavage" NARROW [] +synonym: "stimulation of mRNA cleavage" NARROW [] +synonym: "up regulation of mRNA cleavage" EXACT [] +synonym: "up-regulation of mRNA cleavage" EXACT [] +synonym: "upregulation of mRNA cleavage" EXACT [] +is_a: GO:0031437 ! regulation of mRNA cleavage +is_a: GO:1903313 ! positive regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006379 ! mRNA cleavage +relationship: positively_regulates GO:0006379 ! mRNA cleavage + +[Term] +id: GO:0031440 +name: regulation of mRNA 3'-end processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule." [GOC:mah] +is_a: GO:0050684 ! regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031124 ! mRNA 3'-end processing +relationship: regulates GO:0031124 ! mRNA 3'-end processing + +[Term] +id: GO:0031441 +name: negative regulation of mRNA 3'-end processing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah] +synonym: "down regulation of mRNA 3'-end processing" EXACT [] +synonym: "down-regulation of mRNA 3'-end processing" EXACT [] +synonym: "downregulation of mRNA 3'-end processing" EXACT [] +synonym: "inhibition of mRNA 3'-end processing" NARROW [] +is_a: GO:0031440 ! regulation of mRNA 3'-end processing +is_a: GO:0050686 ! negative regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031124 ! mRNA 3'-end processing +relationship: negatively_regulates GO:0031124 ! mRNA 3'-end processing + +[Term] +id: GO:0031442 +name: positive regulation of mRNA 3'-end processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah] +synonym: "activation of mRNA 3'-end processing" NARROW [] +synonym: "stimulation of mRNA 3'-end processing" NARROW [] +synonym: "up regulation of mRNA 3'-end processing" EXACT [] +synonym: "up-regulation of mRNA 3'-end processing" EXACT [] +synonym: "upregulation of mRNA 3'-end processing" EXACT [] +is_a: GO:0031440 ! regulation of mRNA 3'-end processing +is_a: GO:0050685 ! positive regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031124 ! mRNA 3'-end processing +relationship: positively_regulates GO:0031124 ! mRNA 3'-end processing + +[Term] +id: GO:0031443 +name: fast-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability." [GOC:ef, GOC:mah, GOC:mtg_muscle] +synonym: "fast-twitch skeletal fiber contraction" EXACT [] +synonym: "fast-twitch skeletal fibre contraction" EXACT [] +synonym: "fast-twitch skeletal muscle fibre contraction" EXACT [] +synonym: "fast-twitch skeletal myofiber contraction" EXACT [] +synonym: "fast-twitch skeletal myofibre contraction" EXACT [] +is_a: GO:0014721 ! twitch skeletal muscle contraction + +[Term] +id: GO:0031444 +name: slow-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue." [GOC:ef, GOC:mah, GOC:mtg_muscle] +synonym: "slow-twitch skeletal muscle fibre contraction" EXACT [] +is_a: GO:0014721 ! twitch skeletal muscle contraction + +[Term] +id: GO:0031445 +name: regulation of heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate, extent or location of heterochromatin formation." [GOC:mah] +synonym: "regulation of heterochromatin formation" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0010847 ! regulation of chromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031507 ! heterochromatin assembly +relationship: regulates GO:0031507 ! heterochromatin assembly + +[Term] +id: GO:0031446 +name: regulation of fast-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "regulation of fast-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0014724 ! regulation of twitch skeletal muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction +relationship: regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031447 +name: negative regulation of fast-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "down regulation of fast-twitch skeletal muscle contraction" EXACT [] +synonym: "down-regulation of fast-twitch skeletal muscle contraction" EXACT [] +synonym: "downregulation of fast-twitch skeletal muscle contraction" EXACT [] +synonym: "inhibition of fast-twitch skeletal muscle contraction" NARROW [] +synonym: "negative regulation of fast-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031446 ! regulation of fast-twitch skeletal muscle fiber contraction +is_a: GO:0045988 ! negative regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction +relationship: negatively_regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031448 +name: positive regulation of fast-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "activation of fast-twitch skeletal muscle contraction" NARROW [] +synonym: "positive regulation of fast-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of fast-twitch skeletal muscle contraction" NARROW [] +synonym: "up regulation of fast-twitch skeletal muscle contraction" EXACT [] +synonym: "up-regulation of fast-twitch skeletal muscle contraction" EXACT [] +synonym: "upregulation of fast-twitch skeletal muscle contraction" EXACT [] +is_a: GO:0031446 ! regulation of fast-twitch skeletal muscle fiber contraction +is_a: GO:0045989 ! positive regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction +relationship: positively_regulates GO:0031443 ! fast-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031449 +name: regulation of slow-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "regulation of slow-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0014724 ! regulation of twitch skeletal muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction +relationship: regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031450 +name: negative regulation of slow-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "down regulation of slow-twitch skeletal muscle contraction" EXACT [] +synonym: "down-regulation of slow-twitch skeletal muscle contraction" EXACT [] +synonym: "downregulation of slow-twitch skeletal muscle contraction" EXACT [] +synonym: "inhibition of slow-twitch skeletal muscle contraction" NARROW [] +synonym: "negative regulation of slow-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031449 ! regulation of slow-twitch skeletal muscle fiber contraction +is_a: GO:0045988 ! negative regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction +relationship: negatively_regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031451 +name: positive regulation of slow-twitch skeletal muscle fiber contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction." [GOC:dph, GOC:ef, GOC:mah, GOC:mtg_muscle, GOC:tb] +synonym: "activation of slow-twitch skeletal muscle contraction" NARROW [] +synonym: "positive regulation of slow-twitch skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of slow-twitch skeletal muscle contraction" NARROW [] +synonym: "up regulation of slow-twitch skeletal muscle contraction" EXACT [] +synonym: "up-regulation of slow-twitch skeletal muscle contraction" EXACT [] +synonym: "upregulation of slow-twitch skeletal muscle contraction" EXACT [] +is_a: GO:0031449 ! regulation of slow-twitch skeletal muscle fiber contraction +is_a: GO:0045989 ! positive regulation of striated muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction +relationship: positively_regulates GO:0031444 ! slow-twitch skeletal muscle fiber contraction + +[Term] +id: GO:0031452 +name: negative regulation of heterochromatin assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation." [GOC:mah] +synonym: "down regulation of heterochromatin formation" EXACT [] +synonym: "down-regulation of heterochromatin formation" EXACT [] +synonym: "downregulation of heterochromatin formation" EXACT [] +synonym: "inhibition of heterochromatin formation" NARROW [] +synonym: "negative regulation of heterochromatin formation" EXACT [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +is_a: GO:0045798 ! negative regulation of chromatin assembly or disassembly +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031507 ! heterochromatin assembly +relationship: negatively_regulates GO:0031507 ! heterochromatin assembly + +[Term] +id: GO:0031453 +name: positive regulation of heterochromatin assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heterochromatin formation." [GOC:mah] +synonym: "activation of heterochromatin formation" NARROW [] +synonym: "positive regulation of heterochromatin formation" EXACT [] +synonym: "stimulation of heterochromatin formation" NARROW [] +synonym: "up regulation of heterochromatin formation" EXACT [] +synonym: "up-regulation of heterochromatin formation" EXACT [] +synonym: "upregulation of heterochromatin formation" EXACT [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0045799 ! positive regulation of chromatin assembly or disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031507 ! heterochromatin assembly +relationship: positively_regulates GO:0031507 ! heterochromatin assembly + +[Term] +id: GO:0031454 +name: regulation of extent of heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the extent or location of heterochromatin formation." [GOC:mah] +synonym: "regulation of extent of heterochromatin formation" EXACT [] +synonym: "regulation of heterochromatin spreading" RELATED [] +is_a: GO:0031445 ! regulation of heterochromatin assembly + +[Term] +id: GO:0031455 +name: glycine betaine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycine betaine, N-trimethylglycine." [GOC:mah] +synonym: "glycine betaine metabolism" EXACT [] +synonym: "N-trimethylglycine metabolic process" EXACT [] +synonym: "N-trimethylglycine metabolism" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process + +[Term] +id: GO:0031456 +name: glycine betaine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine." [GOC:mah] +synonym: "glycine betaine anabolism" EXACT [] +synonym: "glycine betaine biosynthesis" EXACT [] +synonym: "glycine betaine formation" EXACT [] +synonym: "glycine betaine synthesis" EXACT [] +synonym: "N-trimethylglycine biosynthesis" EXACT [] +synonym: "N-trimethylglycine biosynthetic process" EXACT [] +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0031455 ! glycine betaine metabolic process + +[Term] +id: GO:0031457 +name: glycine betaine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine." [GOC:mah] +synonym: "glycine betaine breakdown" EXACT [] +synonym: "glycine betaine catabolism" EXACT [] +synonym: "glycine betaine degradation" EXACT [] +synonym: "N-trimethylglycine catabolic process" EXACT [] +synonym: "N-trimethylglycine catabolism" EXACT [] +is_a: GO:0006579 ! amino-acid betaine catabolic process +is_a: GO:0031455 ! glycine betaine metabolic process + +[Term] +id: GO:0031458 +name: ATPase-coupled betaine transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in)." [GOC:mlg] +synonym: "ATP-dependent betaine transporter activity" EXACT [] +synonym: "betaine ABC transporter" NARROW [] +synonym: "betaine-transporting ATPase activity" EXACT [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0031459 +name: ATPase-coupled glycine betaine transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in)." [GOC:mlg] +synonym: "ATP-dependent glycine betaine transporter activity" EXACT [] +synonym: "glycine betaine ABC transporter" NARROW [] +synonym: "glycine betaine-transporting ATPase activity" EXACT [] +synonym: "N-trimethylglycine-transporting ATPase activity" EXACT [] +xref: RHEA:32783 +is_a: GO:0015199 ! amino-acid betaine transmembrane transporter activity +is_a: GO:0015418 ! ATPase-coupled quaternary ammonium compound transmembrane transporting activity +relationship: part_of GO:0031460 ! glycine betaine transport + +[Term] +id: GO:0031460 +name: glycine betaine transport +namespace: biological_process +def: "The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "N-trimethylglycine transport" EXACT [] +is_a: GO:0015838 ! amino-acid betaine transport + +[Term] +id: GO:0031461 +name: cullin-RING ubiquitin ligase complex +namespace: cellular_component +def: "Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity." [PMID:15571813, PMID:15688063] +synonym: "CRL complex" EXACT [] +synonym: "cullin complex" EXACT [] +synonym: "cullin-RING ligase" RELATED [] +is_a: GO:0000151 ! ubiquitin ligase complex + +[Term] +id: GO:0031462 +name: Cul2-RING ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063] +synonym: "CBC complex" BROAD [] +synonym: "CDL2 complex" EXACT [] +synonym: "CRL2 complex" EXACT [] +synonym: "cullin-RING ligase 2" EXACT [] +synonym: "EC2S complex" BROAD [] +synonym: "ECS complex" BROAD [] +synonym: "SCF2 complex" RELATED [] +synonym: "VBC complex" NARROW [] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0031463 +name: Cul3-RING ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein." [PMID:15571813, PMID:15688063] +synonym: "BC3B complex" EXACT [] +synonym: "BCR3 complex" EXACT [] +synonym: "CDL3 complex" EXACT [] +synonym: "CRL3 complex" EXACT [] +synonym: "cullin-RING ligase 3" EXACT [] +synonym: "SCF3 complex" RELATED [] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0031464 +name: Cul4A-RING E3 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein." [PMID:15571813, PMID:15688063] +synonym: "CDL4 complex" EXACT [] +synonym: "CRL4 complex" EXACT [] +synonym: "cullin-RING ligase 4A" EXACT [] +synonym: "DCX complex" EXACT [] +synonym: "SCF4 complex" RELATED [] +synonym: "VDC complex" NARROW [] +is_a: GO:0080008 ! Cul4-RING E3 ubiquitin ligase complex + +[Term] +id: GO:0031465 +name: Cul4B-RING E3 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits." [PMID:15571813, PMID:15688063] +synonym: "cullin-RING ligase 4B" EXACT [] +is_a: GO:0080008 ! Cul4-RING E3 ubiquitin ligase complex + +[Term] +id: GO:0031466 +name: Cul5-RING ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063] +synonym: "CDL5 complex" EXACT [] +synonym: "CRL5 complex" EXACT [] +synonym: "cullin-RING ligase 5" EXACT [] +synonym: "EC2S complex" BROAD [] +synonym: "SCF5 complex" RELATED [] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0031467 +name: Cul7-RING ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein." [PMID:15571813, PMID:15688063] +synonym: "CDL7 complex" EXACT [] +synonym: "CRL7 complex" EXACT [] +synonym: "cullin-RING ligase 7" EXACT [] +synonym: "SCF7 complex" EXACT [] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0031468 +name: nuclear envelope reassembly +namespace: biological_process +def: "The reformation of the nuclear envelope following its breakdown in the context of a normal process." [GOC:mah] +is_a: GO:0006998 ! nuclear envelope organization + +[Term] +id: GO:0031469 +name: polyhedral organelle +namespace: cellular_component +def: "An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081] +subset: goslim_pir +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0031470 +name: carboxysome +namespace: cellular_component +def: "An organelle consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide including mechanisms for the concentration of carbonate to increase the efficiency of fixation under low-carbon dioxide conditions." [GOC:js, PMID:8157606, PMID:8491708] +xref: Wikipedia:Carboxysome +is_a: GO:0031469 ! polyhedral organelle + +[Term] +id: GO:0031471 +name: ethanolamine degradation polyhedral organelle +namespace: cellular_component +def: "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase." [GOC:js, PMID:11844753] +synonym: "ethanolamine metabolosome" RELATED [] +is_a: GO:0031469 ! polyhedral organelle + +[Term] +id: GO:0031472 +name: propanediol degradation polyhedral organelle +namespace: cellular_component +def: "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081] +is_a: GO:0031469 ! polyhedral organelle + +[Term] +id: GO:0031473 +name: myosin III binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class III myosin; myosin III is monomeric and has an N terminal kinase domain." [GOC:mah] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0031474 +name: myosin IV complex +namespace: cellular_component +def: "A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV." [Wikipedia:Myosin] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031475 +name: myosin V complex +namespace: cellular_component +def: "A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region." [Wikipedia:Myosin] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031476 +name: myosin VI complex +namespace: cellular_component +def: "A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031477 +name: myosin VII complex +namespace: cellular_component +def: "A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031478 +name: myosin VIII complex +namespace: cellular_component +def: "A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031479 +name: myosin IX complex +namespace: cellular_component +def: "A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031480 +name: myosin X complex +namespace: cellular_component +def: "A myosin complex containing one or more class X myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031481 +name: myosin XI complex +namespace: cellular_component +def: "A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031482 +name: myosin XII complex +namespace: cellular_component +def: "A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031483 +name: myosin XIII complex +namespace: cellular_component +def: "A myosin complex containing one or more class XIII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031484 +name: myosin XIV complex +namespace: cellular_component +def: "A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031485 +name: myosin XV complex +namespace: cellular_component +def: "A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031486 +name: myosin XVI complex +namespace: cellular_component +def: "A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:11294886] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031487 +name: myosin XVII complex +namespace: cellular_component +def: "A myosin complex containing one or more class XVII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031488 +name: myosin XVIII complex +namespace: cellular_component +def: "A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain." [PMID:11294886] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0031489 +name: myosin V binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0031490 +name: chromatin DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA that is assembled into chromatin." [GOC:mah] +is_a: GO:0003677 ! DNA binding +is_a: GO:0003682 ! chromatin binding + +[Term] +id: GO:0031491 +name: nucleosome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures." [GOC:mah] +is_a: GO:0003682 ! chromatin binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0031492 +name: nucleosomal DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the DNA portion of a nucleosome." [GOC:mah] +is_a: GO:0031490 ! chromatin DNA binding +is_a: GO:0031491 ! nucleosome binding + +[Term] +id: GO:0031493 +name: nucleosomal histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone that is assembled into a nucleosome." [GOC:mah] +is_a: GO:0031491 ! nucleosome binding +is_a: GO:0042393 ! histone binding + +[Term] +id: GO:0031494 +name: regulation of mating type switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [GOC:mah] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007533 ! mating type switching +relationship: regulates GO:0007533 ! mating type switching + +[Term] +id: GO:0031495 +name: negative regulation of mating type switching +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching." [GOC:mah] +synonym: "down regulation of mating type switching" EXACT [] +synonym: "down-regulation of mating type switching" EXACT [] +synonym: "downregulation of mating type switching" EXACT [] +synonym: "inhibition of mating type switching" NARROW [] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0031494 ! regulation of mating type switching +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007533 ! mating type switching +relationship: negatively_regulates GO:0007533 ! mating type switching + +[Term] +id: GO:0031496 +name: positive regulation of mating type switching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mating type switching." [GOC:mah] +synonym: "activation of mating type switching" NARROW [] +synonym: "stimulation of mating type switching" NARROW [] +synonym: "up regulation of mating type switching" EXACT [] +synonym: "up-regulation of mating type switching" EXACT [] +synonym: "upregulation of mating type switching" EXACT [] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:0031494 ! regulation of mating type switching +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007533 ! mating type switching +relationship: positively_regulates GO:0007533 ! mating type switching + +[Term] +id: GO:0031497 +name: chromatin assembly +namespace: biological_process +def: "The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus." [http://www.infobiogen.fr/services/chromcancer/IntroItems/ChromatinEducEng.html, PMID:20404130] +synonym: "establishment of chromatin architecture" EXACT [GOC:mah] +is_a: GO:0006333 ! chromatin assembly or disassembly +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0006323 ! DNA packaging + +[Term] +id: GO:0031498 +name: chromatin disassembly +namespace: biological_process +def: "The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA." [http://www.infobiogen.fr/services/chromcancer/IntroItems/ChromatinEducEng.html, PMID:20404130] +is_a: GO:0006333 ! chromatin assembly or disassembly +is_a: GO:0022411 ! cellular component disassembly + +[Term] +id: GO:0031499 +name: TRAMP complex +namespace: cellular_component +def: "A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control." [PMID:15173578, PMID:15828860, PMID:15935758, PMID:15935759, PMID:16373491, PMID:16374505, PMID:16431988, PMID:16973437, PMID:17410208, PMID:17652137] +synonym: "TRAMP4 complex" NARROW [] +synonym: "TRAMP5 complex" NARROW [] +synonym: "Trf4 complex" NARROW [] +synonym: "Trf4 poly(A) polymerase complex" NARROW [] +synonym: "Trf4p-Air2p-Mtr4p polyadenylation complex" NARROW [] +xref: Wikipedia:TRAMP_complex +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031500 +name: Tea1 cell-end complex +namespace: cellular_component +def: "A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity." [PMID:15936270] +is_a: GO:0005875 ! microtubule associated complex +relationship: part_of GO:0000133 ! polarisome + +[Term] +id: GO:0031501 +name: mannosyltransferase complex +namespace: cellular_component +def: "A complex that posseses mannosyltransferase activity." [GOC:mah] +subset: goslim_pir +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031502 +name: dolichyl-phosphate-mannose-protein mannosyltransferase complex +namespace: cellular_component +def: "A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies." [GOC:mah, GOC:pr, PMID:15948957] +comment: Note that GO:0004169 'dolichyl-phosphate-mannose-protein mannosyltransferase activity' (part of protein O-linked mannosylation) has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543. +synonym: "PMT family mannosyltransferase complex" RELATED [] +synonym: "protein O-mannosyltransferase complex" EXACT [] +is_a: GO:0031501 ! mannosyltransferase complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +property_value: RO:0002161 NCBITaxon:33090 + +[Term] +id: GO:0031503 +name: protein-containing complex localization +namespace: biological_process +def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of protein complex localization" EXACT [] +synonym: "protein complex localisation" EXACT [GOC:mah] +synonym: "protein complex localization" RELATED [] +is_a: GO:0008104 ! protein localization + +[Term] +id: GO:0031504 +name: peptidoglycan-based cell wall organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall." [GOC:dph, GOC:jl, GOC:mah, GOC:mtg_sensu] +synonym: "peptidoglycan-based cell wall organisation" EXACT [GOC:mah] +synonym: "peptidoglycan-based cell wall organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071555 ! cell wall organization + +[Term] +id: GO:0031505 +name: fungal-type cell wall organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GOC:dph, GOC:jl, GOC:mah, GOC:mtg_sensu] +synonym: "beta-glucan-containing cell wall organization and biogenesis" RELATED [] +synonym: "chitin- and beta-glucan-containing cell wall organisation" NARROW [] +synonym: "chitin- and beta-glucan-containing cell wall organization and biogenesis" NARROW [] +synonym: "chitin-containing cell wall organization and biogenesis" RELATED [] +synonym: "fungal-type cell wall organization and biogenesis" RELATED [] +is_a: GO:0071555 ! cell wall organization +is_a: GO:0071852 ! fungal-type cell wall organization or biogenesis + +[Term] +id: GO:0031506 +name: cell wall glycoprotein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues." [GOC:mah] +synonym: "cell wall glycoprotein anabolism" EXACT [] +synonym: "cell wall glycoprotein biosynthesis" EXACT [] +synonym: "cell wall glycoprotein formation" EXACT [] +synonym: "cell wall glycoprotein synthesis" EXACT [] +is_a: GO:0009101 ! glycoprotein biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process + +[Term] +id: GO:0031507 +name: heterochromatin assembly +namespace: biological_process +alt_id: GO:0006343 +alt_id: GO:0070869 +alt_id: GO:1904497 +def: "The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent." [GOC:mah] +synonym: "establishment of chromatin silencing" RELATED [] +synonym: "establishment of heterochromatic silencing" RELATED [] +synonym: "establishment of heterochromatin architecture" EXACT [GOC:mah] +synonym: "establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region" NARROW [GOC:TermGenie] +synonym: "establishment of heterochromatin architecture involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] +synonym: "heterochromatin assembly involved in chromatin silencing" RELATED [] +synonym: "heterochromatin assembly involved in chromatin silencing at centromere outer repeat region" NARROW [] +synonym: "heterochromatin assembly involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] +synonym: "heterochromatin formation" EXACT [] +synonym: "heterochromatin formation involved in chromatin silencing" RELATED [] +synonym: "heterochromatin formation involved in chromatin silencing at centromere outer repeat region" NARROW [GOC:TermGenie] +synonym: "heterochromatin formation involved in chromatin silencing at pericentric region" NARROW [GOC:TermGenie] +is_a: GO:0006338 ! chromatin remodeling +is_a: GO:0031497 ! chromatin assembly +is_a: GO:0051276 ! chromosome organization +is_a: GO:0070828 ! heterochromatin organization +is_a: GO:0097549 ! chromatin organization involved in negative regulation of transcription +relationship: part_of GO:0097549 ! chromatin organization involved in negative regulation of transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18954 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI + +[Term] +id: GO:0031508 +name: pericentric heterochromatin assembly +namespace: biological_process +alt_id: GO:0030702 +alt_id: GO:1990141 +def: "The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA." [GOC:mah, PMID:20206496, PMID:22729156] +synonym: "centric heterochromatin formation" RELATED [] +synonym: "centromere chromatin silencing" EXACT [GOC:mah] +synonym: "centromeric heterochromatin biosynthesis" EXACT [] +synonym: "centromeric heterochromatin formation" EXACT [] +synonym: "centromeric silencing" EXACT [GOC:vw] +synonym: "chromatin silencing at centromere" EXACT [] +synonym: "chromatin silencing at centromere outer repeat region" NARROW [] +synonym: "chromatin silencing at pericentric region" RELATED [GOC:mah] +synonym: "heterochromatic silencing at centromere" EXACT [] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0031055 ! chromatin remodeling at centromere +is_a: GO:0031507 ! heterochromatin assembly +relationship: part_of GO:0034508 ! centromere complex assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18954 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: mah +creation_date: 2013-07-17T15:21:38Z + +[Term] +id: GO:0031509 +name: subtelomeric heterochromatin assembly +namespace: biological_process +alt_id: GO:0035390 +alt_id: GO:0099114 +def: "The assembly of chromatin into heterochromatin at the subtelomeric region." [GOC:mah, PMID:26205977] +synonym: "chromatin silencing at subtelomere" RELATED [] +synonym: "establishment of chromatin silencing at telomere" RELATED [] +synonym: "heterochromatic silencing at subtelomere" RELATED [] +synonym: "subtelomere chromatin silencing" RELATED [GOC:mah] +synonym: "subtelomeric silencing" EXACT [GOC:mah] +synonym: "telomeric heterochromatin assembly" RELATED [] +synonym: "telomeric heterochromatin formation" RELATED [] +is_a: GO:0031507 ! heterochromatin assembly +relationship: part_of GO:0032200 ! telomere organization +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19188 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19308 xsd:anyURI + +[Term] +id: GO:0031510 +name: SUMO activating enzyme complex +namespace: cellular_component +def: "A conserved heterodimeric complex with SUMO activating enzyme activity." [PMID:15601841] +synonym: "SAE" EXACT [] +synonym: "SUMO E1 activator enzyme complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031511 +name: Mis6-Sim4 complex +namespace: cellular_component +def: "A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human." [GOC:vw, PMID:12719471, PMID:15897182] +synonym: "Mis6 centromere subcomplex" NARROW [] +synonym: "Mis6-Mal2-Sim4 centromere complex" EXACT [GOC:vw, PMID:21445296] +synonym: "Sim4 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000939 ! condensed chromosome inner kinetochore + +[Term] +id: GO:0031514 +name: motile cilium +namespace: cellular_component +alt_id: GO:0009434 +alt_id: GO:0031512 +def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] +synonym: "microtubule-based flagellum" RELATED [] +synonym: "motile cilia" EXACT [] +synonym: "motile primary cilia" RELATED [] +synonym: "motile primary cilium" RELATED [] +synonym: "motile secondary cilium" RELATED [] +synonym: "nodal cilium" RELATED [] +is_a: GO:0005929 ! cilium + +[Term] +id: GO:0031515 +name: tRNA (m1A) methyltransferase complex +namespace: cellular_component +def: "A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer." [PMID:10779558, PMID:14739239] +is_a: GO:0043527 ! tRNA methyltransferase complex + +[Term] +id: GO:0031516 +name: far-red light photoreceptor activity +namespace: molecular_function +def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation." [GOC:nln] +is_a: GO:0009883 ! red or far-red light photoreceptor activity +relationship: part_of GO:0010018 ! far-red light signaling pathway + +[Term] +id: GO:0031517 +name: red light photoreceptor activity +namespace: molecular_function +def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation." [GOC:nln] +is_a: GO:0009883 ! red or far-red light photoreceptor activity +relationship: part_of GO:0010161 ! red light signaling pathway + +[Term] +id: GO:0031518 +name: CBF3 complex +namespace: cellular_component +def: "A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p." [PMID:13679521, PMID:9407032] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0031519 +name: PcG protein complex +namespace: cellular_component +def: "A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure." [PMID:9372908] +subset: goslim_pir +synonym: "Polycomb Group protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031520 +name: plasma membrane of cell tip +namespace: cellular_component +def: "The portion of the plasma membrane surrounding the cell tip." [GOC:mah] +synonym: "'plasma membrane, cell tip'" EXACT [] +is_a: GO:0098590 ! plasma membrane region +intersection_of: GO:0098590 ! plasma membrane region +intersection_of: part_of GO:0051286 ! cell tip +relationship: part_of GO:0051286 ! cell tip + +[Term] +id: GO:0031521 +name: spitzenkorper +namespace: cellular_component +def: "Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments." [PMID:15701784, PMID:15976451] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0001411 ! hyphal tip +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0031522 +name: cell envelope Sec protein transport complex +namespace: cellular_component +def: "A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC." [GOC:mtg_sensu, PMID:15223057] +comment: Note that this term represents the protein complex involved in transport of proteins across the cytoplasmic membrane. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'type II protein secretion complex ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'endoplasmic reticulum Sec complex ; GO:0031205'. +synonym: "plasma membrane Sec complex" RELATED [] +synonym: "Sec complex" BROAD [] +synonym: "Sec secretion complex" NARROW [] +synonym: "Sec translocation complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0031523 +name: Myb complex +namespace: cellular_component +def: "A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression." [PMID:12490953, PMID:15545624] +synonym: "Myeloblastosis proto-oncogene protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0031524 +name: menthol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol." [GOC:mah] +synonym: "menthol metabolism" EXACT [] +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0031525 +name: menthol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol." [GOC:mah] +synonym: "menthol anabolism" EXACT [] +synonym: "menthol biosynthesis" EXACT [] +synonym: "menthol formation" EXACT [] +synonym: "menthol synthesis" EXACT [] +is_a: GO:0016099 ! monoterpenoid biosynthetic process +is_a: GO:0031524 ! menthol metabolic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0031526 +name: brush border membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding the brush border." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0005903 ! brush border + +[Term] +id: GO:0031527 +name: filopodium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a filopodium." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0030175 ! filopodium + +[Term] +id: GO:0031528 +name: microvillus membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a microvillus." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0005902 ! microvillus + +[Term] +id: GO:0031529 +name: ruffle organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell." [GOC:mah, PMID:10036235] +synonym: "ruffle organisation" EXACT [GOC:mah] +synonym: "ruffle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization + +[Term] +id: GO:0031530 +name: gonadotropin-releasing hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary." [GOC:pr, PMID:15196882] +synonym: "GnRH receptor binding" EXACT [] +synonym: "gonadotrophin-releasing hormone receptor binding" EXACT [GOC:dph] +is_a: GO:0051428 ! peptide hormone receptor binding + +[Term] +id: GO:0031531 +name: thyrotropin-releasing hormone receptor binding +namespace: molecular_function +alt_id: GO:0031888 +def: "Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary." [PMID:8592728] +synonym: "thyrotropin releasing hormone receptor binding" EXACT [] +synonym: "thyrotropin-releasing hormone receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding +is_a: GO:0051428 ! peptide hormone receptor binding + +[Term] +id: GO:0031532 +name: actin cytoskeleton reorganization +namespace: biological_process +alt_id: GO:0007012 +def: "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ecd, GOC:mah] +synonym: "actin cytoskeleton remodeling" EXACT [] +synonym: "actin cytoskeleton reorganisation" EXACT [] +is_a: GO:0030036 ! actin cytoskeleton organization + +[Term] +id: GO:0031533 +name: mRNA cap methyltransferase complex +namespace: cellular_component +def: "A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping." [GOC:vw, PMID:10347220] +synonym: "mRNA (guanine-N7) methyltransferase complex" EXACT [] +synonym: "mRNA capping enzyme complex" EXACT [GOC:vw] +is_a: GO:0034708 ! methyltransferase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031534 +name: minus-end directed microtubule sliding +namespace: biological_process +def: "The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules." [GOC:mah, GOC:vw] +is_a: GO:0051012 ! microtubule sliding + +[Term] +id: GO:0031535 +name: plus-end directed microtubule sliding +namespace: biological_process +def: "The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules." [GOC:mah, GOC:vw] +is_a: GO:0051012 ! microtubule sliding + +[Term] +id: GO:0031536 +name: positive regulation of exit from mitosis +namespace: biological_process +def: "Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:mah] +synonym: "activation of exit from mitosis" NARROW [] +synonym: "stimulation of exit from mitosis" NARROW [] +synonym: "up regulation of exit from mitosis" EXACT [] +synonym: "up-regulation of exit from mitosis" EXACT [] +synonym: "upregulation of exit from mitosis" EXACT [] +is_a: GO:0007096 ! regulation of exit from mitosis +is_a: GO:0045840 ! positive regulation of mitotic nuclear division +is_a: GO:1901992 ! positive regulation of mitotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010458 ! exit from mitosis +relationship: positively_regulates GO:0010458 ! exit from mitosis + +[Term] +id: GO:0031537 +name: regulation of anthocyanin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] +synonym: "regulation of anthocyanin metabolism" EXACT [] +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046283 ! anthocyanin-containing compound metabolic process +relationship: regulates GO:0046283 ! anthocyanin-containing compound metabolic process + +[Term] +id: GO:0031538 +name: negative regulation of anthocyanin metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] +synonym: "down regulation of anthocyanin metabolic process" EXACT [] +synonym: "down-regulation of anthocyanin metabolic process" EXACT [] +synonym: "downregulation of anthocyanin metabolic process" EXACT [] +synonym: "inhibition of anthocyanin metabolic process" NARROW [] +synonym: "negative regulation of anthocyanin metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0031537 ! regulation of anthocyanin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046283 ! anthocyanin-containing compound metabolic process +relationship: negatively_regulates GO:0046283 ! anthocyanin-containing compound metabolic process + +[Term] +id: GO:0031539 +name: positive regulation of anthocyanin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] +synonym: "activation of anthocyanin metabolic process" NARROW [] +synonym: "positive regulation of anthocyanin metabolism" EXACT [] +synonym: "stimulation of anthocyanin metabolic process" NARROW [] +synonym: "up regulation of anthocyanin metabolic process" EXACT [] +synonym: "up-regulation of anthocyanin metabolic process" EXACT [] +synonym: "upregulation of anthocyanin metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0031537 ! regulation of anthocyanin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046283 ! anthocyanin-containing compound metabolic process +relationship: positively_regulates GO:0046283 ! anthocyanin-containing compound metabolic process + +[Term] +id: GO:0031540 +name: regulation of anthocyanin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] +synonym: "regulation of anthocyanin anabolism" EXACT [] +synonym: "regulation of anthocyanin biosynthesis" EXACT [] +synonym: "regulation of anthocyanin formation" EXACT [] +synonym: "regulation of anthocyanin synthesis" EXACT [] +is_a: GO:0009962 ! regulation of flavonoid biosynthetic process +is_a: GO:0031537 ! regulation of anthocyanin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process +relationship: regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process + +[Term] +id: GO:0031541 +name: negative regulation of anthocyanin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] +synonym: "down regulation of anthocyanin biosynthetic process" EXACT [] +synonym: "down-regulation of anthocyanin biosynthetic process" EXACT [] +synonym: "downregulation of anthocyanin biosynthetic process" EXACT [] +synonym: "inhibition of anthocyanin biosynthetic process" NARROW [] +synonym: "negative regulation of anthocyanin anabolism" EXACT [] +synonym: "negative regulation of anthocyanin biosynthesis" EXACT [] +synonym: "negative regulation of anthocyanin formation" EXACT [] +synonym: "negative regulation of anthocyanin synthesis" EXACT [] +is_a: GO:0009964 ! negative regulation of flavonoid biosynthetic process +is_a: GO:0031538 ! negative regulation of anthocyanin metabolic process +is_a: GO:0031540 ! regulation of anthocyanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process +relationship: negatively_regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process + +[Term] +id: GO:0031542 +name: positive regulation of anthocyanin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] +synonym: "activation of anthocyanin biosynthetic process" NARROW [] +synonym: "positive regulation of anthocyanin anabolism" EXACT [] +synonym: "positive regulation of anthocyanin biosynthesis" EXACT [] +synonym: "positive regulation of anthocyanin formation" EXACT [] +synonym: "positive regulation of anthocyanin synthesis" EXACT [] +synonym: "stimulation of anthocyanin biosynthetic process" NARROW [] +synonym: "up regulation of anthocyanin biosynthetic process" EXACT [] +synonym: "up-regulation of anthocyanin biosynthetic process" EXACT [] +synonym: "upregulation of anthocyanin biosynthetic process" EXACT [] +is_a: GO:0009963 ! positive regulation of flavonoid biosynthetic process +is_a: GO:0031539 ! positive regulation of anthocyanin metabolic process +is_a: GO:0031540 ! regulation of anthocyanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process +relationship: positively_regulates GO:0009718 ! anthocyanin-containing compound biosynthetic process + +[Term] +id: GO:0031543 +name: peptidyl-proline dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2." [GOC:mah, GOC:vw, PMID:24550447, PMID:24550462] +synonym: "proline hydroxylase activity" BROAD [GOC:krc, GOC:pr] +synonym: "proline,2-oxoglutarate 4-dioxygenase activity" BROAD [GOC:krc, GOC:pr] +synonym: "prolyl 4-hydroxylase activity" BROAD [GOC:krc, GOC:pr] +synonym: "prolyl hydroxylase activity" BROAD [GOC:krc, GOC:pr] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0019511 ! peptidyl-proline hydroxylation + +[Term] +id: GO:0031544 +name: peptidyl-proline 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2." [GOC:mah] +is_a: GO:0031543 ! peptidyl-proline dioxygenase activity + +[Term] +id: GO:0031545 +name: peptidyl-proline 4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2." [GOC:mah] +synonym: "HIF-type prolyl 4-hydroxylase" NARROW [] +synonym: "prolyl 4-hydroxylase" BROAD [] +xref: Reactome:R-HSA-1234165 "Nuclear PHD1,3 hydroxylates proline residues on HIF3A" +xref: Reactome:R-HSA-1234166 "Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A)" +xref: Reactome:R-HSA-1234173 "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A" +xref: Reactome:R-HSA-1234177 "Cytosolic PHD2,3 hydroxylates proline residues on HIF1A" +xref: Reactome:R-HSA-1234179 "Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A)" +xref: Reactome:R-HSA-1234181 "Nuclear PHD1,3 hydroxylates proline residues on HIF1A" +is_a: GO:0031543 ! peptidyl-proline dioxygenase activity + +[Term] +id: GO:0031546 +name: brain-derived neurotrophic factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the brain-derived neurotrophic factor receptor." [GOC:mah] +synonym: "BDNF receptor binding" EXACT [] +synonym: "brain-derived neurotrophic factor ligand" NARROW [] +is_a: GO:0005165 ! neurotrophin receptor binding + +[Term] +id: GO:0031547 +name: brain-derived neurotrophic factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "BDNF receptor signaling pathway" EXACT [] +synonym: "BDNF signalling pathway" EXACT [] +synonym: "brain-derived neurotrophic factor receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031548 +name: regulation of brain-derived neurotrophic factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] +synonym: "regulation of BDNF receptor signaling pathway" EXACT [] +synonym: "regulation of BDNF receptor signalling pathway" EXACT [] +synonym: "regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +relationship: regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031549 +name: negative regulation of brain-derived neurotrophic factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] +synonym: "down regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +synonym: "downregulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +synonym: "inhibition of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of BDNF receptor signaling pathway" EXACT [] +synonym: "negative regulation of BDNF receptor signalling pathway" EXACT [] +synonym: "negative regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0031548 ! regulation of brain-derived neurotrophic factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +relationship: negatively_regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031550 +name: positive regulation of brain-derived neurotrophic factor receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] +synonym: "activation of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of BDNF receptor signaling pathway" EXACT [] +synonym: "positive regulation of BDNF receptor signalling pathway" EXACT [] +synonym: "positive regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] +synonym: "stimulation of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] +synonym: "up regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +synonym: "upregulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0031548 ! regulation of brain-derived neurotrophic factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +relationship: positively_regulates GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031551 +name: regulation of brain-derived neurotrophic factor-activated receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah] +synonym: "regulation of BDNF receptor activity" EXACT [] +synonym: "regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0031548 ! regulation of brain-derived neurotrophic factor receptor signaling pathway +is_a: GO:0061097 ! regulation of protein tyrosine kinase activity +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity +relationship: regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity + +[Term] +id: GO:0031552 +name: negative regulation of brain-derived neurotrophic factor-activated receptor activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah] +synonym: "down regulation of brain-derived neurotrophic factor receptor activity" EXACT [] +synonym: "down-regulation of brain-derived neurotrophic factor receptor activity" EXACT [] +synonym: "downregulation of brain-derived neurotrophic factor receptor activity" EXACT [] +synonym: "inhibition of brain-derived neurotrophic factor receptor activity" NARROW [] +synonym: "negative regulation of BDNF receptor activity" EXACT [] +synonym: "negative regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0031549 ! negative regulation of brain-derived neurotrophic factor receptor signaling pathway +is_a: GO:0031551 ! regulation of brain-derived neurotrophic factor-activated receptor activity +is_a: GO:0061099 ! negative regulation of protein tyrosine kinase activity +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity +relationship: negatively_regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity + +[Term] +id: GO:0031553 +name: positive regulation of brain-derived neurotrophic factor-activated receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity." [GOC:mah] +synonym: "activation of brain-derived neurotrophic factor receptor activity" NARROW [] +synonym: "positive regulation of BDNF receptor activity" EXACT [] +synonym: "positive regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "stimulation of brain-derived neurotrophic factor receptor activity" NARROW [] +synonym: "up regulation of brain-derived neurotrophic factor receptor activity" EXACT [] +synonym: "up-regulation of brain-derived neurotrophic factor receptor activity" EXACT [] +synonym: "upregulation of brain-derived neurotrophic factor receptor activity" EXACT [] +is_a: GO:0031550 ! positive regulation of brain-derived neurotrophic factor receptor signaling pathway +is_a: GO:0031551 ! regulation of brain-derived neurotrophic factor-activated receptor activity +is_a: GO:0061098 ! positive regulation of protein tyrosine kinase activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity +relationship: positively_regulates GO:0060175 ! brain-derived neurotrophic factor-activated receptor activity + +[Term] +id: GO:0031554 +name: regulation of DNA-templated transcription, termination +namespace: biological_process +def: "Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:mlg, GOC:txnOH] +synonym: "regulation of DNA-dependent transcription, termination" EXACT [GOC:txnOH] +synonym: "regulation of termination of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "regulation of transcription termination, DNA-dependent" EXACT [GOC:jh2] +synonym: "transcription antiterminator activity" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006353 ! DNA-templated transcription, termination +relationship: regulates GO:0006353 ! DNA-templated transcription, termination + +[Term] +id: GO:0031555 +name: transcriptional attenuation +namespace: biological_process +def: "Regulation of transcription through variation in where transcription termination occurs." [GOC:dh, GOC:mlg, ISBN:0198542682] +xref: Wikipedia:Attenuator_(genetics) +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0031556 +name: transcriptional attenuation by ribosome +namespace: biological_process +def: "A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch." [GOC:dh, GOC:mlg, ISBN:0198542682] +synonym: "ribosome-mediated transcriptional attenuation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031555 ! transcriptional attenuation +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0031557 +name: obsolete induction of programmed cell death in response to chemical stimulus +namespace: biological_process +def: "OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus." [GOC:mah, GOC:mtg_apoptosis] +comment: This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0012501 programmed cell death. +synonym: "induction of programmed cell death in response to chemical stimulus" EXACT [] +synonym: "induction of programmed cell death in response to chemical substance" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031558 +name: obsolete induction of apoptosis in response to chemical stimulus +namespace: biological_process +def: "OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus." [GOC:mah, GOC:mtg_apoptosis] +comment: This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0006915 apoptotic process. +synonym: "induction of apoptosis in response to chemical stimulus" EXACT [] +synonym: "induction of apoptosis in response to chemical substance" EXACT [] +is_obsolete: true + +[Term] +id: GO:0031559 +name: oxidosqualene cyclase activity +namespace: molecular_function +def: "Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene." [GOC:ct] +comment: Note that the phrase 'oxidosqualene cyclase' has been used to refer to enzymes that catalyze the reaction represented by 'lanosterol synthase activity ; GO:0000250'. +synonym: "2,3-oxidosqualene cyclase activity" EXACT [GOC:mah] +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0031560 +name: cellular bud neck polarisome +namespace: cellular_component +def: "Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis." [PMID:9632790] +is_a: GO:0000133 ! polarisome +intersection_of: GO:0000133 ! polarisome +intersection_of: part_of GO:0005935 ! cellular bud neck +relationship: part_of GO:0005935 ! cellular bud neck + +[Term] +id: GO:0031561 +name: cellular bud tip polarisome +namespace: cellular_component +def: "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud." [PMID:9632790] +is_a: GO:0000133 ! polarisome +intersection_of: GO:0000133 ! polarisome +intersection_of: part_of GO:0005934 ! cellular bud tip +relationship: part_of GO:0005934 ! cellular bud tip + +[Term] +id: GO:0031562 +name: hyphal tip polarisome +namespace: cellular_component +def: "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha." [PMID:15976451] +is_a: GO:0000133 ! polarisome +intersection_of: GO:0000133 ! polarisome +intersection_of: part_of GO:0001411 ! hyphal tip +relationship: part_of GO:0001411 ! hyphal tip + +[Term] +id: GO:0031563 +name: mating projection tip polarisome +namespace: cellular_component +def: "Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone." [PMID:14734532] +is_a: GO:0000133 ! polarisome +intersection_of: GO:0000133 ! polarisome +intersection_of: part_of GO:0043332 ! mating projection tip +relationship: part_of GO:0043332 ! mating projection tip + +[Term] +id: GO:0031564 +name: transcription antitermination +namespace: biological_process +def: "Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s)." [ISBN:0198577788, PMID:12456320] +synonym: "transcriptional readthrough" EXACT [] +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination + +[Term] +id: GO:0031565 +name: obsolete cytokinesis checkpoint +namespace: biological_process +alt_id: GO:0000135 +def: "OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition." [GOC:mtg_cell_cycle] +comment: The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning. +synonym: "contractile ring checkpoint" EXACT [] +synonym: "septin checkpoint" EXACT [] +is_obsolete: true +consider: GO:0044878 +consider: GO:0044879 + +[Term] +id: GO:0031566 +name: actomyosin contractile ring maintenance +namespace: biological_process +def: "The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle." [GOC:dph, GOC:mah, GOC:tb, GOC:vw] +synonym: "contractile ring maintenance involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0036212 ! contractile ring maintenance +is_a: GO:0044837 ! actomyosin contractile ring organization + +[Term] +id: GO:0031567 +name: mitotic cell size control checkpoint +namespace: biological_process +def: "The mitotic cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle cell size control checkpoint" EXACT [GOC:mah] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +intersection_of: GO:0007093 ! mitotic cell cycle checkpoint +intersection_of: part_of GO:0008361 ! regulation of cell size +relationship: part_of GO:0008361 ! regulation of cell size + +[Term] +id: GO:0031568 +name: G1 cell size control checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G1 and S phase until a critical size is reached." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G1/S transition size control checkpoint" EXACT [] +synonym: "mitotic G1 cell size control checkpoint" EXACT [] +is_a: GO:0031567 ! mitotic cell size control checkpoint +is_a: GO:2000134 ! negative regulation of G1/S transition of mitotic cell cycle +intersection_of: GO:0031567 ! mitotic cell size control checkpoint +intersection_of: negatively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle + +[Term] +id: GO:0031569 +name: mitotic G2 cell size control checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G2 and M phase until a critical size is reached." [GOC:mtg_cell_cycle] +synonym: "G2 cell size control checkpoint" EXACT [] +synonym: "G2/M transition size control checkpoint" EXACT [] +synonym: "mitotic cell cycle G2/M transition size control checkpoint" EXACT [GOC:mah] +is_a: GO:0010972 ! negative regulation of G2/M transition of mitotic cell cycle +is_a: GO:0031567 ! mitotic cell size control checkpoint +intersection_of: GO:0031567 ! mitotic cell size control checkpoint +intersection_of: happens_during GO:0051319 ! G2 phase +intersection_of: negatively_regulates GO:0000086 ! G2/M transition of mitotic cell cycle +relationship: happens_during GO:0051319 ! G2 phase + +[Term] +id: GO:0031570 +name: DNA integrity checkpoint +namespace: biological_process +def: "A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes." [GOC:mtg_cell_cycle] +is_a: GO:0000075 ! cell cycle checkpoint + +[Term] +id: GO:0031571 +name: mitotic G1 DNA damage checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S transition of the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [] +is_a: GO:0044773 ! mitotic DNA damage checkpoint +is_a: GO:0044783 ! G1 DNA damage checkpoint +is_a: GO:0044819 ! mitotic G1/S transition checkpoint +intersection_of: GO:0044783 ! G1 DNA damage checkpoint +intersection_of: negatively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle + +[Term] +id: GO:0031572 +name: G2 DNA damage checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] +comment: Note that this term should only be used as a grouping term for the mitotic and meiotic G2 DNA damage checkpoints, and should not be used for direct manual annotation. You should always be able to choose one of its child terms instead. +subset: gocheck_do_not_manually_annotate +synonym: "G2/M transition DNA damage checkpoint" EXACT [] +is_a: GO:0000077 ! DNA damage checkpoint + +[Term] +id: GO:0031573 +name: intra-S DNA damage checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression." [GOC:vw] +synonym: "mitotic intra-S DNA damage checkpoint" EXACT [] +synonym: "S-phase checkpoint" BROAD [] +is_a: GO:0044773 ! mitotic DNA damage checkpoint + +[Term] +id: GO:0031577 +name: spindle checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that originates from the mitotic or meiotic spindle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term. +subset: gocheck_do_not_manually_annotate +xref: Wikipedia:Spindle_checkpoint +is_a: GO:0000075 ! cell cycle checkpoint + +[Term] +id: GO:0031578 +name: mitotic spindle orientation checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected." [GOC:mtg_cell_cycle, PMID:14616062] +synonym: "mitotic cell cycle spindle orientation checkpoint" EXACT [] +synonym: "SOC" EXACT [] +synonym: "spindle position checkpoint" EXACT [] +synonym: "SPOC" EXACT [] +is_a: GO:0001100 ! negative regulation of exit from mitosis +is_a: GO:0071174 ! mitotic spindle checkpoint + +[Term] +id: GO:0031579 +name: membrane raft organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:dph, GOC:jl, GOC:mah] +synonym: "lipid raft organization" EXACT [GOC:mah] +synonym: "membrane raft organisation" EXACT [GOC:mah] +synonym: "membrane raft organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization + +[Term] +id: GO:0031580 +name: membrane raft distribution +namespace: biological_process +def: "The process that establishes the spatial arrangement of membrane rafts within a cellular membrane." [GOC:mah] +synonym: "lipid raft distribution" EXACT [] +is_a: GO:0031579 ! membrane raft organization +is_a: GO:0051665 ! membrane raft localization + +[Term] +id: GO:0031581 +name: hemidesmosome assembly +namespace: biological_process +def: "Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina." [GOC:dgh, PMID:15983403] +is_a: GO:0007044 ! cell-substrate junction assembly + +[Term] +id: GO:0031582 +name: replication fork arrest at rDNA repeats +namespace: biological_process +def: "A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer." [GOC:mah, GOC:vw] +synonym: "replication fork arrest at ribosomal DNA repeats" EXACT [] +synonym: "replication fork blocking at rDNA repeats" EXACT [] +is_a: GO:0043007 ! maintenance of rDNA +is_a: GO:0043111 ! replication fork arrest + +[Term] +id: GO:0031583 +name: phospholipase D-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA)." [GOC:mah, GOC:signaling, PMID:11812783, PMID:15924269] +comment: This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase D (PLD) activation. +synonym: "activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway" RELATED [GOC:signaling] +synonym: "G-protein signalling, phospholipase D activating pathway" EXACT [] +synonym: "phospholipase D-activating G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: has_part GO:0031584 ! activation of phospholipase D activity + +[Term] +id: GO:0031584 +name: activation of phospholipase D activity +namespace: biological_process +def: "Any process that initiates the activity of inactive phospholipase D." [GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0010518 ! positive regulation of phospholipase activity + +[Term] +id: GO:0031585 +name: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling] +synonym: "regulation of inositol-1,4,5-triphosphate receptor activity" EXACT [GOC:signaling] +synonym: "regulation of IP3 receptor activity" EXACT [GOC:dph] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +relationship: regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity + +[Term] +id: GO:0031586 +name: negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling] +synonym: "down regulation of IP3 receptor activity" EXACT [] +synonym: "down-regulation of IP3 receptor activity" EXACT [] +synonym: "downregulation of IP3 receptor activity" EXACT [] +synonym: "inhibition of IP3 receptor activity" NARROW [] +synonym: "negative regulation of inositol 1,4,5-trisphosphate receptor activity" EXACT [GOC:signaling] +synonym: "negative regulation of IP3 receptor activity" RELATED [GOC:dph] +is_a: GO:0031585 ! regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +is_a: GO:0050849 ! negative regulation of calcium-mediated signaling +is_a: GO:0051280 ! negative regulation of release of sequestered calcium ion into cytosol +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +relationship: negatively_regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity + +[Term] +id: GO:0031587 +name: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling] +synonym: "activation of IP3 receptor activity" NARROW [] +synonym: "positive regulation of inositol-1,4,5-trisphosphate receptor activity" EXACT [GOC:bf] +synonym: "positive regulation of IP3 receptor activity" EXACT [GOC:dph] +synonym: "stimulation of IP3 receptor activity" NARROW [] +synonym: "up regulation of IP3 receptor activity" EXACT [] +synonym: "up-regulation of IP3 receptor activity" EXACT [] +synonym: "upregulation of IP3 receptor activity" EXACT [] +is_a: GO:0031585 ! regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +is_a: GO:0051281 ! positive regulation of release of sequestered calcium ion into cytosol +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +relationship: positively_regulates GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity + +[Term] +id: GO:0031588 +name: nucleotide-activated protein kinase complex +namespace: cellular_component +def: "A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae)." [GOC:bhm, GOC:mah, GOC:vw] +synonym: "5'-AMP-activated protein kinase complex" NARROW [] +synonym: "ADP-activated protein kinase complex" NARROW [] +synonym: "AMP-activated protein kinase complex" NARROW [] +synonym: "AMPK complex" RELATED [] +synonym: "Snf1 kinase complex" NARROW [] +synonym: "Snf1 serine/threonine protein kinase complex" NARROW [] +synonym: "SNF1/AMPK protein kinase complex" NARROW [] +is_a: GO:1902911 ! protein kinase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0031589 +name: cell-substrate adhesion +namespace: biological_process +def: "The attachment of a cell to the underlying substrate via adhesion molecules." [GOC:mah, GOC:pf] +is_a: GO:0007155 ! cell adhesion + +[Term] +id: GO:0031590 +name: wybutosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules." [GOC:mah, RNAmods:037] +synonym: "wybutosine metabolism" EXACT [] +synonym: "yW metabolic process" EXACT [] +synonym: "yW metabolism" EXACT [] +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901657 ! glycosyl compound metabolic process + +[Term] +id: GO:0031591 +name: wybutosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules." [GOC:hjd, GOC:mah, RNAmods:037] +comment: Note that wybutosine is a hypermodified G-residue, formerly called the Y-base, and its derivatives are exclusively found at position 37 (anticodon loop) of tRNAPhe. +synonym: "yW biosynthesis" EXACT [] +synonym: "yW biosynthetic process" EXACT [] +is_a: GO:0006400 ! tRNA modification +is_a: GO:0031590 ! wybutosine metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901659 ! glycosyl compound biosynthetic process + +[Term] +id: GO:0031592 +name: centrosomal corona +namespace: cellular_component +def: "An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin." [GOC:kp, GOC:mah] +comment: Note that the centrosomal corona has been observed in Dictyostelium, and is the functional equivalent of pericentriolar material. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005813 ! centrosome + +[Term] +id: GO:0031593 +name: polyubiquitin modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon poly-ubiquitination of the target protein." [GOC:pg] +is_a: GO:0140030 ! modification-dependent protein binding + +[Term] +id: GO:0031594 +name: neuromuscular junction +namespace: cellular_component +def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln] +comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT. +synonym: "motor endplate" RELATED [NIF_Subcellular:nlx_subcell_20090512] +synonym: "NMJ" RELATED [GOC:ha] +xref: NIF_Subcellular:sao1124888485 +xref: Wikipedia:Neuromuscular_junction +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0031595 +name: nuclear proteasome complex +namespace: cellular_component +def: "A proteasome found in the nucleus of a cell." [GOC:mah] +is_a: GO:0000502 ! proteasome complex +intersection_of: GO:0000502 ! proteasome complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0031596 +name: obsolete ER proteasome complex +namespace: cellular_component +def: "OBSOLETE. A proteasome found in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031597 +name: cytosolic proteasome complex +namespace: cellular_component +def: "A proteasome complex found in the cytosol of a cell." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0000502 ! proteasome complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0031598 +name: nuclear proteasome regulatory particle +namespace: cellular_component +def: "The regulatory subcomplex of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0005838 ! proteasome regulatory particle +intersection_of: GO:0005838 ! proteasome regulatory particle +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031595 ! nuclear proteasome complex + +[Term] +id: GO:0031599 +name: obsolete ER proteasome regulatory particle +namespace: cellular_component +def: "OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031600 +name: cytosolic proteasome regulatory particle +namespace: cellular_component +def: "A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0005838 ! proteasome regulatory particle +relationship: part_of GO:0031597 ! cytosolic proteasome complex + +[Term] +id: GO:0031601 +name: nuclear proteasome core complex +namespace: cellular_component +def: "The core complex of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0005839 ! proteasome core complex +intersection_of: GO:0005839 ! proteasome core complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031595 ! nuclear proteasome complex + +[Term] +id: GO:0031602 +name: obsolete ER proteasome core complex +namespace: cellular_component +def: "OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031603 +name: cytosolic proteasome core complex +namespace: cellular_component +def: "The core complex of a proteasome located in the cytosol of a cell." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0005839 ! proteasome core complex +relationship: part_of GO:0031597 ! cytosolic proteasome complex + +[Term] +id: GO:0031604 +name: nuclear proteasome core complex, alpha-subunit complex +namespace: cellular_component +def: "The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0019773 ! proteasome core complex, alpha-subunit complex +intersection_of: GO:0019773 ! proteasome core complex, alpha-subunit complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031601 ! nuclear proteasome core complex + +[Term] +id: GO:0031605 +name: obsolete ER proteasome core complex, alpha-subunit complex +namespace: cellular_component +def: "OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031606 +name: cytosolic proteasome core complex, alpha-subunit complex +namespace: cellular_component +def: "The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0019773 ! proteasome core complex, alpha-subunit complex +relationship: part_of GO:0031603 ! cytosolic proteasome core complex + +[Term] +id: GO:0031607 +name: nuclear proteasome core complex, beta-subunit complex +namespace: cellular_component +def: "The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0019774 ! proteasome core complex, beta-subunit complex +intersection_of: GO:0019774 ! proteasome core complex, beta-subunit complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031601 ! nuclear proteasome core complex + +[Term] +id: GO:0031608 +name: obsolete ER proteasome core complex, beta-subunit complex +namespace: cellular_component +def: "OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031609 +name: cytosolic proteasome core complex, beta-subunit complex +namespace: cellular_component +def: "The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0019774 ! proteasome core complex, beta-subunit complex +relationship: part_of GO:0031603 ! cytosolic proteasome core complex + +[Term] +id: GO:0031610 +name: nuclear proteasome regulatory particle, base subcomplex +namespace: cellular_component +def: "The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0008540 ! proteasome regulatory particle, base subcomplex +intersection_of: GO:0008540 ! proteasome regulatory particle, base subcomplex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031598 ! nuclear proteasome regulatory particle + +[Term] +id: GO:0031611 +name: obsolete ER proteasome regulatory particle, base subcomplex +namespace: cellular_component +def: "OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031612 +name: cytosolic proteasome regulatory particle, base subcomplex +namespace: cellular_component +def: "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0008540 ! proteasome regulatory particle, base subcomplex +relationship: part_of GO:0031600 ! cytosolic proteasome regulatory particle + +[Term] +id: GO:0031613 +name: nuclear proteasome regulatory particle, lid subcomplex +namespace: cellular_component +def: "The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell." [GOC:mah] +is_a: GO:0008541 ! proteasome regulatory particle, lid subcomplex +intersection_of: GO:0008541 ! proteasome regulatory particle, lid subcomplex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0031598 ! nuclear proteasome regulatory particle + +[Term] +id: GO:0031614 +name: obsolete ER proteasome regulatory particle, lid subcomplex +namespace: cellular_component +def: "OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] +comment: This term was made obsolete because there is no evidence in the literature of its existence. +is_obsolete: true + +[Term] +id: GO:0031615 +name: cytosolic proteasome regulatory particle, lid subcomplex +namespace: cellular_component +def: "The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:mah, GOC:mtg_sensu] +is_a: GO:0008541 ! proteasome regulatory particle, lid subcomplex +relationship: part_of GO:0031600 ! cytosolic proteasome regulatory particle + +[Term] +id: GO:0031616 +name: spindle pole centrosome +namespace: cellular_component +def: "A centrosome from which one pole of a mitotic or meiotic spindle is organized." [GOC:mah] +is_a: GO:0005813 ! centrosome +intersection_of: GO:0005813 ! centrosome +intersection_of: part_of GO:0000922 ! spindle pole +relationship: part_of GO:0000922 ! spindle pole + +[Term] +id: GO:0031617 +name: NMS complex +namespace: cellular_component +def: "A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes." [PMID:16079914] +synonym: "KMN kinetochore network" EXACT [] +synonym: "KNL-1-Mis12-Ndc80" EXACT [] +synonym: "Ndc80-MIND-Spc7 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000776 ! kinetochore + +[Term] +id: GO:0031618 +name: nuclear pericentric heterochromatin +namespace: cellular_component +alt_id: GO:0002137 +def: "Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3." [GOC:mah, PMID:20206496, PMID:22729156, PMID:9413993] +synonym: "nuclear centric heterochromatin" EXACT [] +synonym: "nuclear cluster" NARROW [] +is_a: GO:0005720 ! nuclear heterochromatin +is_a: GO:0005721 ! pericentric heterochromatin +intersection_of: GO:0005721 ! pericentric heterochromatin +intersection_of: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031619 +name: homologous chromosome orientation involved in meiotic metaphase I plate congression +namespace: biological_process +def: "The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:15062096] +synonym: "homologous chromosome orientation during meiosis" RELATED [GOC:dph, GOC:tb] +synonym: "homologous chromosome orientation during meiosis I" RELATED [] +is_a: GO:0051455 ! monopolar spindle attachment to meiosis I kinetochore +relationship: part_of GO:0043060 ! meiotic metaphase I plate congression + +[Term] +id: GO:0031620 +name: regulation of fever generation +namespace: biological_process +def: "Any process that modulates the rate or extent of fever generation." [GOC:add, GOC:dph, GOC:tb] +synonym: "regulation of pyrexia" EXACT [] +is_a: GO:0002673 ! regulation of acute inflammatory response +is_a: GO:0031650 ! regulation of heat generation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001660 ! fever generation +relationship: regulates GO:0001660 ! fever generation + +[Term] +id: GO:0031621 +name: negative regulation of fever generation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of fever generation." [GOC:add, GOC:dph, GOC:tb] +synonym: "down regulation of fever" EXACT [] +synonym: "down-regulation of fever" EXACT [] +synonym: "downregulation of fever" EXACT [] +synonym: "inhibition of fever" NARROW [] +synonym: "negative regulation of pyrexia" EXACT [] +is_a: GO:0002674 ! negative regulation of acute inflammatory response +is_a: GO:0031620 ! regulation of fever generation +is_a: GO:0031651 ! negative regulation of heat generation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001660 ! fever generation +relationship: negatively_regulates GO:0001660 ! fever generation + +[Term] +id: GO:0031622 +name: positive regulation of fever generation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of fever generation." [GOC:add] +synonym: "activation of fever" NARROW [] +synonym: "positive regulation of pyrexia" EXACT [] +synonym: "stimulation of fever" NARROW [] +synonym: "up regulation of fever" EXACT [] +synonym: "up-regulation of fever" EXACT [] +synonym: "upregulation of fever" EXACT [] +is_a: GO:0002675 ! positive regulation of acute inflammatory response +is_a: GO:0031620 ! regulation of fever generation +is_a: GO:0031652 ! positive regulation of heat generation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001660 ! fever generation +relationship: positively_regulates GO:0001660 ! fever generation + +[Term] +id: GO:0031623 +name: receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane." [GOC:bf, GOC:mah, GOC:signaling, PMID:15006537, PMID:19643732] +is_a: GO:0006898 ! receptor-mediated endocytosis +is_a: GO:0043112 ! receptor metabolic process + +[Term] +id: GO:0031624 +name: ubiquitin conjugating enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins." [GOC:vp] +is_a: GO:0044390 ! ubiquitin-like protein conjugating enzyme binding + +[Term] +id: GO:0031625 +name: ubiquitin protein ligase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins." [GOC:vp] +synonym: "ubiquitin ligase binding" EXACT [] +is_a: GO:0044389 ! ubiquitin-like protein ligase binding + +[Term] +id: GO:0031626 +name: beta-endorphin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin." [GOC:nln, PMID:6267560] +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0031627 +name: telomeric loop formation +namespace: biological_process +def: "The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region." [GOC:vw, PMID:10338214] +synonym: "T loop biosynthesis" EXACT [] +synonym: "T loop formation" EXACT [] +synonym: "t-loop biosynthesis" EXACT [] +synonym: "t-loop formation" EXACT [] +is_a: GO:0000723 ! telomere maintenance + +[Term] +id: GO:0031628 +name: opioid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an opioid receptor." [GOC:nln] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031629 +name: synaptic vesicle fusion to presynaptic active zone membrane +namespace: biological_process +def: "Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] +subset: goslim_synapse +synonym: "synaptic vesicle fusion" BROAD [] +synonym: "synaptic vesicle fusion to pre-synaptic membrane" EXACT [] +synonym: "synaptic vesicle fusion to presynaptic membrane" EXACT [] +is_a: GO:0099500 ! vesicle fusion to plasma membrane +relationship: part_of GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0031630 +name: regulation of synaptic vesicle fusion to presynaptic active zone membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] +subset: goslim_synapse +synonym: "regulation of synaptic vesicle fusion to pre-synaptic membrane" EXACT [] +synonym: "regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] +is_a: GO:0031338 ! regulation of vesicle fusion +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane +relationship: regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane + +[Term] +id: GO:0031631 +name: negative regulation of synaptic vesicle fusion to presynaptic active zone membrane +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] +synonym: "down regulation of synaptic vesicle fusion to presynaptic active zone membrane" EXACT [] +synonym: "down regulation of synaptic vesicle fusion to presynaptic membrane" BROAD [] +synonym: "down-regulation of synaptic vesicle fusion to presynaptic active zone membrane" EXACT [] +synonym: "down-regulation of synaptic vesicle fusion to presynaptic membrane" BROAD [] +synonym: "downregulation of synaptic vesicle fusion to presynaptic active zone membrane" EXACT [] +synonym: "downregulation of synaptic vesicle fusion to presynaptic membrane" BROAD [] +synonym: "inhibition of synaptic vesicle fusion to presynaptic membrane" BROAD [] +synonym: "negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane" EXACT [] +synonym: "negative regulation of synaptic vesicle fusion to pre-synaptic membrane" BROAD [] +synonym: "negative regulation of synaptic vesicle fusion to presynaptic membrane" BROAD [] +is_a: GO:0031339 ! negative regulation of vesicle fusion +is_a: GO:0031630 ! regulation of synaptic vesicle fusion to presynaptic active zone membrane +is_a: GO:2000301 ! negative regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane +relationship: negatively_regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane + +[Term] +id: GO:0031632 +name: positive regulation of synaptic vesicle fusion to presynaptic active zone membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] +synonym: "activation of synaptic vesicle fusion to presynaptic membrane" NARROW [] +synonym: "negative regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] +synonym: "positive regulation of synaptic vesicle fusion to pre-synaptic membrane" EXACT [] +synonym: "stimulation of synaptic vesicle fusion to presynaptic membrane" NARROW [] +synonym: "up regulation of synaptic vesicle fusion to presynaptic active zone membrane" EXACT [] +synonym: "up regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] +synonym: "up-regulation of synaptic vesicle fusion to presynaptic active zone membrane" EXACT [] +synonym: "up-regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] +synonym: "upregulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] +is_a: GO:0031340 ! positive regulation of vesicle fusion +is_a: GO:0031630 ! regulation of synaptic vesicle fusion to presynaptic active zone membrane +is_a: GO:2000302 ! positive regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane +relationship: positively_regulates GO:0031629 ! synaptic vesicle fusion to presynaptic active zone membrane + +[Term] +id: GO:0031633 +name: xanthophore +namespace: cellular_component +def: "A chromatophore containing yellow pigment." [ISBN:0395825172] +comment: Note that this term refers to a subcellular structure, and should not be confused with the specialized cells known as xanthophores, which produce yellow pigment and are found in fish and amphibian skin. Note that several terms in the biological process ontology ('xanthophore differentiation ; GO:0050936' and its children) refer to xanthophores in the sense of pigment-producing cells. +is_a: GO:0042716 ! plasma membrane-derived chromatophore + +[Term] +id: GO:0031634 +name: replication fork barrier binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks." [GOC:mah] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding + +[Term] +id: GO:0031635 +name: adenylate cyclase-inhibiting opioid receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:dph, GOC:mah, GOC:signaling, GOC:tb] +synonym: "inhibition of adenylate cyclase activity by opioid receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by opioid receptor signalling pathway" RELATED [GOC:mah] +synonym: "opioid receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0038003 ! opioid receptor signaling pathway + +[Term] +id: GO:0031637 +name: regulation of neuronal synaptic plasticity in response to neurotrophin +namespace: biological_process +def: "The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah, PMID:8703078] +synonym: "neurotrophin-induced neuronal synaptic plasticity" EXACT [] +is_a: GO:0048168 ! regulation of neuronal synaptic plasticity + +[Term] +id: GO:0031638 +name: zymogen activation +namespace: biological_process +def: "The proteolytic processing of an inactive enzyme to an active form." [GOC:hjd] +subset: goslim_chembl +synonym: "zymogen activation by proteolytic cleavage" EXACT [] +is_a: GO:0016485 ! protein processing + +[Term] +id: GO:0031639 +name: plasminogen activation +namespace: biological_process +def: "The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide." [PMID:9548733] +subset: goslim_chembl +synonym: "cleavage of plasminogen to plasmin" EXACT [] +is_a: GO:0031638 ! zymogen activation + +[Term] +id: GO:0031640 +name: killing of cells of other organism +namespace: biological_process +alt_id: GO:0001908 +def: "Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions." [GOC:add] +subset: goslim_pir +synonym: "killing of cells of another organism" EXACT [GOC:bf] +synonym: "killing of cells of another, non-host, organism" NARROW [] +is_a: GO:0001906 ! cell killing + +[Term] +id: GO:0031641 +name: regulation of myelination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042552 ! myelination +relationship: regulates GO:0042552 ! myelination + +[Term] +id: GO:0031642 +name: negative regulation of myelination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] +synonym: "down regulation of myelination" EXACT [] +synonym: "down-regulation of myelination" EXACT [] +synonym: "downregulation of myelination" EXACT [] +synonym: "inhibition of myelination" NARROW [] +is_a: GO:0031641 ! regulation of myelination +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051961 ! negative regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042552 ! myelination +relationship: negatively_regulates GO:0042552 ! myelination + +[Term] +id: GO:0031643 +name: positive regulation of myelination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] +synonym: "activation of myelination" NARROW [] +synonym: "stimulation of myelination" NARROW [] +synonym: "up regulation of myelination" EXACT [] +synonym: "up-regulation of myelination" EXACT [] +synonym: "upregulation of myelination" EXACT [] +is_a: GO:0031641 ! regulation of myelination +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051962 ! positive regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042552 ! myelination +relationship: positively_regulates GO:0042552 ! myelination + +[Term] +id: GO:0031644 +name: regulation of nervous system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of neurological system process" EXACT [] +synonym: "regulation of neurophysiological process" EXACT [] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050877 ! nervous system process +relationship: regulates GO:0050877 ! nervous system process + +[Term] +id: GO:0031645 +name: negative regulation of nervous system process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of neurological process" EXACT [] +synonym: "down-regulation of neurological process" EXACT [] +synonym: "downregulation of neurological process" EXACT [] +synonym: "inhibition of neurological process" NARROW [] +synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of neurological system process" EXACT [] +synonym: "negative regulation of neurophysiological process" EXACT [] +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050877 ! nervous system process +relationship: negatively_regulates GO:0050877 ! nervous system process + +[Term] +id: GO:0031646 +name: positive regulation of nervous system process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] +synonym: "activation of neurological process" NARROW [] +synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of neurological system process" EXACT [] +synonym: "positive regulation of neurophysiological process" EXACT [] +synonym: "stimulation of neurological process" NARROW [] +synonym: "up regulation of neurological process" EXACT [] +synonym: "up-regulation of neurological process" EXACT [] +synonym: "upregulation of neurological process" EXACT [] +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050877 ! nervous system process +relationship: positively_regulates GO:0050877 ! nervous system process + +[Term] +id: GO:0031647 +name: regulation of protein stability +namespace: biological_process +def: "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." [GOC:dph, GOC:mah, GOC:tb] +subset: goslim_pir +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0031648 +name: protein destabilization +namespace: biological_process +def: "Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation." [GOC:mah] +synonym: "negative regulation of protein stability" EXACT [] +synonym: "protein destabilisation" EXACT [GOC:ah] +is_a: GO:0031647 ! regulation of protein stability + +[Term] +id: GO:0031649 +name: heat generation +namespace: biological_process +def: "Any homeostatic process in which an organism produces heat, thereby raising its internal temperature." [GOC:mah] +is_a: GO:0001659 ! temperature homeostasis + +[Term] +id: GO:0031650 +name: regulation of heat generation +namespace: biological_process +def: "Any process that modulates the rate or extent of heat generation." [GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031649 ! heat generation +relationship: regulates GO:0031649 ! heat generation + +[Term] +id: GO:0031651 +name: negative regulation of heat generation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of heat generation." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of heat generation" EXACT [] +synonym: "down-regulation of heat generation" EXACT [] +synonym: "downregulation of heat generation" EXACT [] +synonym: "inhibition of heat generation" NARROW [] +is_a: GO:0031650 ! regulation of heat generation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031649 ! heat generation +relationship: negatively_regulates GO:0031649 ! heat generation + +[Term] +id: GO:0031652 +name: positive regulation of heat generation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of heat generation." [GOC:dph, GOC:mah, GOC:tb] +synonym: "activation of heat generation" NARROW [] +synonym: "stimulation of heat generation" NARROW [] +synonym: "up regulation of heat generation" EXACT [] +synonym: "up-regulation of heat generation" EXACT [] +synonym: "upregulation of heat generation" EXACT [] +is_a: GO:0031650 ! regulation of heat generation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031649 ! heat generation +relationship: positively_regulates GO:0031649 ! heat generation + +[Term] +id: GO:0031653 +name: heat dissipation +namespace: biological_process +def: "Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature." [GOC:mah] +is_a: GO:0001659 ! temperature homeostasis + +[Term] +id: GO:0031654 +name: regulation of heat dissipation +namespace: biological_process +def: "Any process that modulates the rate or extent of heat dissipation." [GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031653 ! heat dissipation +relationship: regulates GO:0031653 ! heat dissipation + +[Term] +id: GO:0031655 +name: negative regulation of heat dissipation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate or extent of heat dissipation." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of heat dissipation" EXACT [] +synonym: "down-regulation of heat dissipation" EXACT [] +synonym: "downregulation of heat dissipation" EXACT [] +synonym: "inhibition of heat dissipation" NARROW [] +is_a: GO:0031654 ! regulation of heat dissipation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031653 ! heat dissipation +relationship: negatively_regulates GO:0031653 ! heat dissipation + +[Term] +id: GO:0031656 +name: positive regulation of heat dissipation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of heat dissipation." [GOC:dph, GOC:mah, GOC:tb] +synonym: "activation of heat dissipation" NARROW [] +synonym: "stimulation of heat dissipation" NARROW [] +synonym: "up regulation of heat dissipation" EXACT [] +synonym: "up-regulation of heat dissipation" EXACT [] +synonym: "upregulation of heat dissipation" EXACT [] +is_a: GO:0031654 ! regulation of heat dissipation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031653 ! heat dissipation +relationship: positively_regulates GO:0031653 ! heat dissipation + +[Term] +id: GO:0031657 +name: obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:mtg_cell_cycle, GOC:pr] +comment: The term has been obsoleted because it represents a GO-CAM model. +synonym: "G1/S-specific regulation of cyclin-dependent protein kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of cyclin-dependent protein kinase activity during G1/S" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of cyclin-dependent protein kinase activity involved in G1/S" BROAD [] +is_obsolete: true + +[Term] +id: GO:0031658 +name: obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb] +comment: The term has been obsoleted because it represents a GO-CAM model. +synonym: "G1/S-specific down regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G1/S-specific down-regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G1/S-specific downregulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G1/S-specific inhibition of cyclin-dependent protein kinase activity" NARROW [] +synonym: "G1/S-specific negative regulation of cyclin-dependent protein kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of cyclin-dependent protein kinase activity during G1/S" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of cyclin-dependent protein kinase activity involved in G1/S" BROAD [] +is_obsolete: true + +[Term] +id: GO:0031659 +name: obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb] +comment: The term has been obsoleted because it represents a GO-CAM model. +synonym: "G1/S-specific activation of cyclin-dependent protein kinase activity" NARROW [] +synonym: "G1/S-specific positive regulation of cyclin-dependent protein kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "G1/S-specific stimulation of cyclin-dependent protein kinase activity" NARROW [] +synonym: "G1/S-specific up regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G1/S-specific up-regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G1/S-specific upregulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "positive regulation of cyclin-dependent protein kinase activity during G1/S" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of cyclin-dependent protein kinase activity involved in G1/S" BROAD [] +is_obsolete: true + +[Term] +id: GO:0031660 +name: regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb] +synonym: "G2/M-specific regulation of cyclin-dependent protein kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of cyclin-dependent protein kinase activity during G2/M" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of cyclin-dependent protein kinase activity involved in G2/M" BROAD [] +is_a: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity +is_a: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle +intersection_of: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity +intersection_of: regulates GO:0000086 ! G2/M transition of mitotic cell cycle + +[Term] +id: GO:0031661 +name: negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle." [GOC:dph, GOC:mah, GOC:pr, GOC:tb] +synonym: "G2/M-specific down regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G2/M-specific down-regulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G2/M-specific downregulation of cyclin-dependent protein kinase activity" EXACT [] +synonym: "G2/M-specific inhibition of cyclin-dependent protein kinase activity" NARROW [] +synonym: "G2/M-specific negative regulation of cyclin-dependent protein kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of cyclin-dependent protein kinase activity during G2/M" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of cyclin-dependent protein kinase activity involved in G2/M" BROAD [] +is_a: GO:0031660 ! regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle +is_a: GO:0045736 ! negative regulation of cyclin-dependent protein serine/threonine kinase activity +intersection_of: GO:0045736 ! negative regulation of cyclin-dependent protein serine/threonine kinase activity +intersection_of: regulates GO:0000086 ! G2/M transition of mitotic cell cycle + +[Term] +id: GO:0031663 +name: lipopolysaccharide-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system." [GOC:mah, GOC:signaling, PMID:15379975] +synonym: "lipopolysaccharide-mediated signalling pathway" EXACT [] +synonym: "LPS-mediated signaling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway +relationship: part_of GO:0071222 ! cellular response to lipopolysaccharide + +[Term] +id: GO:0031664 +name: regulation of lipopolysaccharide-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] +synonym: "regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] +synonym: "regulation of LPS-mediated signaling pathway" EXACT [] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway +relationship: regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway + +[Term] +id: GO:0031665 +name: negative regulation of lipopolysaccharide-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] +synonym: "down regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +synonym: "down-regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +synonym: "downregulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +synonym: "inhibition of lipopolysaccharide-mediated signaling pathway" NARROW [] +synonym: "negative regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] +synonym: "negative regulation of LPS-mediated signaling pathway" EXACT [] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0031664 ! regulation of lipopolysaccharide-mediated signaling pathway +is_a: GO:0032102 ! negative regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway +relationship: negatively_regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway + +[Term] +id: GO:0031666 +name: positive regulation of lipopolysaccharide-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] +synonym: "activation of lipopolysaccharide-mediated signaling pathway" NARROW [] +synonym: "positive regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] +synonym: "positive regulation of LPS-mediated signaling pathway" EXACT [] +synonym: "stimulation of lipopolysaccharide-mediated signaling pathway" NARROW [] +synonym: "up regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +synonym: "up-regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +synonym: "upregulation of lipopolysaccharide-mediated signaling pathway" EXACT [] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0031664 ! regulation of lipopolysaccharide-mediated signaling pathway +is_a: GO:0032103 ! positive regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway +relationship: positively_regulates GO:0031663 ! lipopolysaccharide-mediated signaling pathway + +[Term] +id: GO:0031667 +name: response to nutrient levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." [GOC:mah] +is_a: GO:0009991 ! response to extracellular stimulus + +[Term] +id: GO:0031668 +name: cellular response to extracellular stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus." [GOC:mah] +is_a: GO:0007154 ! cell communication +is_a: GO:0009991 ! response to extracellular stimulus +is_a: GO:0051716 ! cellular response to stimulus +is_a: GO:0071496 ! cellular response to external stimulus + +[Term] +id: GO:0031669 +name: cellular response to nutrient levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." [GOC:mah] +is_a: GO:0031667 ! response to nutrient levels +is_a: GO:0031668 ! cellular response to extracellular stimulus + +[Term] +id: GO:0031670 +name: cellular response to nutrient +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus." [GOC:mah] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0031669 ! cellular response to nutrient levels +is_a: GO:0070887 ! cellular response to chemical stimulus + +[Term] +id: GO:0031671 +name: primary cell septum biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division." [GOC:jl] +is_a: GO:0044085 ! cellular component biogenesis +is_a: GO:1902410 ! mitotic cytokinetic process +relationship: part_of GO:0140278 ! mitotic division septum assembly + +[Term] +id: GO:0031672 +name: A band +namespace: cellular_component +def: "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." [ISBN:0321204131] +synonym: "A disc" EXACT [] +synonym: "anisotropic disc" EXACT [] +synonym: "Q disc" EXACT [] +synonym: "transverse disc" EXACT [] +xref: Wikipedia:Sarcomere#bands +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030017 ! sarcomere + +[Term] +id: GO:0031673 +name: H zone +namespace: cellular_component +def: "A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments." [GOC:mtg_muscle, ISBN:0321204131] +synonym: "H band" EXACT [] +synonym: "H disc" EXACT [] +xref: Wikipedia:Sarcomere#bands +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031672 ! A band + +[Term] +id: GO:0031674 +name: I band +namespace: cellular_component +def: "A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end." [ISBN:0321204131] +synonym: "I disc" EXACT [] +synonym: "isotropic disc" EXACT [] +synonym: "J disc" EXACT [] +xref: Wikipedia:Sarcomere#bands +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030017 ! sarcomere + +[Term] +id: GO:0031676 +name: plasma membrane-derived thylakoid membrane +namespace: cellular_component +def: "The pigmented membrane of a plasma membrane-derived thylakoid." [GOC:mah, GOC:mtg_sensu] +synonym: "plasma membrane thylakoid membrane" EXACT [] +is_a: GO:0042651 ! thylakoid membrane +is_a: GO:0042717 ! plasma membrane-derived chromatophore membrane +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0030075 ! bacterial thylakoid + +[Term] +id: GO:0031679 +name: NADH dehydrogenase (plastoquinone) activity +namespace: molecular_function +alt_id: GO:0030024 +def: "Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol." [EC:1.6.99.6, GOC:mah] +synonym: "NADH:plastoquinone reductase activity" EXACT [] +is_a: GO:0050136 ! NADH dehydrogenase (quinone) activity + +[Term] +id: GO:0031680 +name: G-protein beta/gamma-subunit complex +namespace: cellular_component +def: "The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange." [GOC:mah] +comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'. +synonym: "G-beta/G-gamma complex" EXACT [] +synonym: "heterotrimeric G-protein GTPase, beta-subunit" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0031681 +name: G-protein beta-subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G-protein beta subunit." [GOC:mah] +synonym: "G-beta protein subunit binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0031682 +name: G-protein gamma-subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G-protein gamma subunit." [GOC:mah] +synonym: "G-gamma protein subunit binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0031683 +name: G-protein beta/gamma-subunit complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits." [GOC:nln, GOC:vw] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0031684 +name: obsolete heterotrimeric G-protein complex cycle +namespace: biological_process +def: "OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits." [GOC:nln] +comment: The reason for obsoleting is that it is an arbitrary grouping term that groups the molecular functions required for the G-protein complex cycle, and this is not a bona fide biological process. +is_obsolete: true + +[Term] +id: GO:0031685 +name: adenosine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adenosine receptor." [GOC:mah, GOC:nln] +synonym: "adenosine receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031686 +name: A1 adenosine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an A1 adenosine receptor." [GOC:mah, GOC:nln] +synonym: "A1 adenosine receptor ligand" NARROW [] +is_a: GO:0031685 ! adenosine receptor binding + +[Term] +id: GO:0031687 +name: A2A adenosine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an A2A adenosine receptor." [GOC:mah, GOC:nln] +synonym: "A2A adenosine receptor ligand" NARROW [] +is_a: GO:0031685 ! adenosine receptor binding + +[Term] +id: GO:0031688 +name: A2B adenosine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an A2B adenosine receptor." [GOC:mah, GOC:nln] +synonym: "A2B adenosine receptor ligand" NARROW [] +is_a: GO:0031685 ! adenosine receptor binding + +[Term] +id: GO:0031689 +name: A3 adenosine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an A3 adenosine receptor." [GOC:mah, GOC:nln] +synonym: "A3 adenosine receptor ligand" NARROW [] +is_a: GO:0031685 ! adenosine receptor binding + +[Term] +id: GO:0031690 +name: adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "adrenergic receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031691 +name: alpha-1A adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-1A adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-1A adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031692 +name: alpha-1B adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-1B adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-1B adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031693 +name: alpha-1D adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-1D adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-1D adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031694 +name: alpha-2A adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-2A adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-2A adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031695 +name: alpha-2B adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-2B adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-2B adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031696 +name: alpha-2C adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-2C adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "alpha-2C adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031697 +name: beta-1 adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a beta-1 adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "beta-1 adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031698 +name: beta-2 adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a beta-2 adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "beta-2 adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031699 +name: beta-3 adrenergic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a beta-3 adrenergic receptor." [GOC:mah, GOC:nln] +synonym: "beta-3 adrenergic receptor ligand" NARROW [] +is_a: GO:0031690 ! adrenergic receptor binding + +[Term] +id: GO:0031700 +name: adrenomedullin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adrenomedullin receptor." [GOC:mah, GOC:nln] +synonym: "adrenomedullin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031701 +name: angiotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an angiotensin receptor." [GOC:mah, GOC:nln] +synonym: "angiotensin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031702 +name: type 1 angiotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 angiotensin receptor." [GOC:mah, GOC:nln] +synonym: "AT1 receptor binding" EXACT [] +synonym: "type 1 angiotensin receptor ligand" NARROW [] +is_a: GO:0031701 ! angiotensin receptor binding + +[Term] +id: GO:0031703 +name: type 2 angiotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 angiotensin receptor." [GOC:mah, GOC:nln] +synonym: "AT2 receptor binding" EXACT [] +synonym: "type 2 angiotensin receptor ligand" NARROW [] +is_a: GO:0031701 ! angiotensin receptor binding + +[Term] +id: GO:0031704 +name: apelin receptor binding +namespace: molecular_function +alt_id: GO:0042569 +def: "Interacting selectively and non-covalently with an apelin receptor." [GOC:mah, GOC:nln, GOC:vp, PMID:12787050] +synonym: "apelin receptor ligand" NARROW [] +synonym: "APJ receptor binding" EXACT [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031705 +name: bombesin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a bombesin receptor." [GOC:mah, GOC:nln] +synonym: "bombesin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031706 +name: subtype 3 bombesin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a subtype 3 bombesin receptor." [GOC:mah, GOC:nln] +synonym: "subtype 3 bombesin receptor ligand" NARROW [] +is_a: GO:0031705 ! bombesin receptor binding + +[Term] +id: GO:0031707 +name: endothelin A receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endothelin A receptor." [GOC:mah, GOC:nln] +synonym: "endothelin A receptor ligand" NARROW [] +synonym: "endothelin-1 receptor binding" EXACT [] +is_a: GO:0031705 ! bombesin receptor binding + +[Term] +id: GO:0031708 +name: endothelin B receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endothelin B receptor." [GOC:mah, GOC:nln] +synonym: "endothelin B receptor ligand" NARROW [] +is_a: GO:0031705 ! bombesin receptor binding + +[Term] +id: GO:0031709 +name: gastrin-releasing peptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a gastrin-releasing peptide receptor." [GOC:mah, GOC:nln] +synonym: "gastrin-releasing peptide receptor ligand" NARROW [] +synonym: "GRP receptor binding" EXACT [] +is_a: GO:0031705 ! bombesin receptor binding + +[Term] +id: GO:0031710 +name: neuromedin B receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuromedin B receptor." [GOC:mah, GOC:nln] +synonym: "neuromedin B receptor ligand" NARROW [] +is_a: GO:0031705 ! bombesin receptor binding + +[Term] +id: GO:0031711 +name: bradykinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a bradykinin receptor." [GOC:mah, GOC:nln] +synonym: "bradykinin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031712 +name: B1 bradykinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a B1 bradykinin receptor." [GOC:mah, GOC:nln] +synonym: "B1 bradykinin receptor ligand" NARROW [] +is_a: GO:0031711 ! bradykinin receptor binding + +[Term] +id: GO:0031713 +name: B2 bradykinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a B2 bradykinin receptor." [GOC:mah, GOC:nln] +synonym: "B2 bradykinin receptor ligand" NARROW [] +is_a: GO:0031711 ! bradykinin receptor binding + +[Term] +id: GO:0031714 +name: C5a anaphylatoxin chemotactic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C5a anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln] +synonym: "C5a anaphylatoxin chemotactic receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031715 +name: C5L2 anaphylatoxin chemotactic receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln] +synonym: "C5L2 anaphylatoxin chemotactic receptor ligand" NARROW [] +is_a: GO:0031714 ! C5a anaphylatoxin chemotactic receptor binding + +[Term] +id: GO:0031716 +name: calcitonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a calcitonin receptor." [GOC:mah, GOC:nln] +synonym: "calcitonin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031717 +name: cannabinoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cannabinoid receptor." [GOC:mah, GOC:nln] +synonym: "cannabinoid receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031718 +name: type 1 cannabinoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 cannabinoid receptor." [GOC:mah, GOC:nln] +synonym: "type 1 cannabinoid receptor ligand" NARROW [] +is_a: GO:0031717 ! cannabinoid receptor binding + +[Term] +id: GO:0031719 +name: type 2 cannabinoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 cannabinoid receptor." [GOC:mah, GOC:nln] +synonym: "type 2 cannabinoid receptor ligand" NARROW [] +is_a: GO:0031717 ! cannabinoid receptor binding + +[Term] +id: GO:0031720 +name: haptoglobin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex." [GOC:mah, ISBN:0198506732] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0031721 +name: hemoglobin alpha binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a hemoglobin alpha chain." [GOC:mah] +is_a: GO:0030492 ! hemoglobin binding + +[Term] +id: GO:0031722 +name: hemoglobin beta binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a hemoglobin beta chain." [GOC:mah] +is_a: GO:0030492 ! hemoglobin binding + +[Term] +id: GO:0031723 +name: CXCR4 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CXCR4 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CXCR4 chemokine receptor ligand" NARROW [] +synonym: "stromal cell-derived factor 1 receptor binding" EXACT [] +is_a: GO:0045236 ! CXCR chemokine receptor binding + +[Term] +id: GO:0031724 +name: CXCR5 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CXCR5 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CXCR5 chemokine receptor ligand" NARROW [] +synonym: "type 1 Burkitt's lymphoma receptor binding" EXACT [] +is_a: GO:0045236 ! CXCR chemokine receptor binding + +[Term] +id: GO:0031725 +name: CXCR6 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CXCR6 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "bonzo receptor binding" EXACT [] +synonym: "CXCR6 chemokine receptor ligand" NARROW [] +synonym: "STRL33 receptor binding" EXACT [] +is_a: GO:0045236 ! CXCR chemokine receptor binding + +[Term] +id: GO:0031726 +name: CCR1 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR1 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR1 chemokine receptor ligand" NARROW [] +synonym: "macrophage inflammatory protein-1 alpha receptor binding" EXACT [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031727 +name: CCR2 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR2 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR2 chemokine receptor ligand" NARROW [] +synonym: "monocyte chemoattractant protein 1 receptor binding" EXACT [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031728 +name: CCR3 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR3 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR3 chemokine receptor ligand" NARROW [] +synonym: "eosinophil eotaxin receptor binding" EXACT [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031729 +name: CCR4 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR4 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR4 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031730 +name: CCR5 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR5 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR5 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031731 +name: CCR6 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR6 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR6 chemokine receptor ligand" NARROW [] +synonym: "LARC receptor binding" EXACT [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031732 +name: CCR7 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR7 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR7 chemokine receptor ligand" NARROW [] +synonym: "MIP-3 beta receptor binding" EXACT [] +synonym: "type 1 EBV-induced G-protein coupled receptor binding" EXACT [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031733 +name: CCR8 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR8 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR8 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031734 +name: CCR9 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR9 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR9 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031735 +name: CCR10 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR10 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR10 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031736 +name: CCR11 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR11 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CCR11 chemokine receptor ligand" NARROW [] +is_a: GO:0048020 ! CCR chemokine receptor binding + +[Term] +id: GO:0031737 +name: CX3C chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CX3C chemokine receptor." [GOC:mah, GOC:nln] +synonym: "CX3C chemokine receptor ligand" NARROW [] +synonym: "fractalkine receptor binding" EXACT [] +is_a: GO:0042379 ! chemokine receptor binding + +[Term] +id: GO:0031738 +name: XCR1 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a XCR1 chemokine receptor." [GOC:mah, GOC:nln] +synonym: "lymphotactin receptor binding" EXACT [] +synonym: "XCR1 chemokine receptor ligand" NARROW [] +is_a: GO:0042379 ! chemokine receptor binding + +[Term] +id: GO:0031739 +name: cholecystokinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cholecystokinin receptor." [GOC:mah, GOC:nln] +synonym: "cholecystokinin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031740 +name: type A cholecystokinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type A cholecystokinin receptor." [GOC:mah, GOC:nln] +synonym: "type A cholecystokinin receptor ligand" NARROW [] +is_a: GO:0031739 ! cholecystokinin receptor binding + +[Term] +id: GO:0031741 +name: type B gastrin/cholecystokinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor." [GOC:mah, GOC:nln] +synonym: "type B gastrin/cholecystokinin receptor ligand" NARROW [] +is_a: GO:0031739 ! cholecystokinin receptor binding + +[Term] +id: GO:0031745 +name: cysteinyl leukotriene receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] +synonym: "cysteinyl leukotriene receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031746 +name: type 1 cysteinyl leukotriene receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] +synonym: "type 1 cysteinyl leukotriene receptor ligand" NARROW [] +is_a: GO:0031745 ! cysteinyl leukotriene receptor binding + +[Term] +id: GO:0031747 +name: type 2 cysteinyl leukotriene receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] +synonym: "type 2 cysteinyl leukotriene receptor ligand" NARROW [] +is_a: GO:0031745 ! cysteinyl leukotriene receptor binding + +[Term] +id: GO:0031748 +name: D1 dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a D1 dopamine receptor." [GOC:mah, GOC:nln] +synonym: "D1 dopamine receptor ligand" NARROW [] +synonym: "D1A dopamine receptor binding" EXACT [] +is_a: GO:0050780 ! dopamine receptor binding + +[Term] +id: GO:0031749 +name: D2 dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a D2 dopamine receptor." [GOC:mah, GOC:nln] +synonym: "D2 dopamine receptor ligand" NARROW [] +is_a: GO:0050780 ! dopamine receptor binding + +[Term] +id: GO:0031750 +name: D3 dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a D3 dopamine receptor." [GOC:mah, GOC:nln] +synonym: "D3 dopamine receptor ligand" NARROW [] +is_a: GO:0050780 ! dopamine receptor binding + +[Term] +id: GO:0031751 +name: D4 dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a D4 dopamine receptor." [GOC:mah, GOC:nln] +synonym: "D4 dopamine receptor ligand" NARROW [] +is_a: GO:0050780 ! dopamine receptor binding + +[Term] +id: GO:0031752 +name: D5 dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a D5 dopamine receptor." [GOC:mah, GOC:nln] +synonym: "D1B dopamine receptor binding" EXACT [] +synonym: "D5 dopamine receptor ligand" NARROW [] +is_a: GO:0050780 ! dopamine receptor binding + +[Term] +id: GO:0031753 +name: endothelial differentiation G protein-coupled receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endothelial differentiation G protein-coupled receptor." [GOC:mah, GOC:nln] +synonym: "endothelial differentiation G-protein coupled receptor binding" EXACT [] +synonym: "endothelial differentiation G-protein coupled receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031754 +name: Edg-1 sphingosine 1-phosphate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-1 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] +synonym: "Edg-1 sphingosine 1-phosphate receptor ligand" NARROW [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031755 +name: Edg-2 lysophosphatidic acid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-2 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] +synonym: "Edg-2 lysophosphatidic acid receptor ligand" NARROW [] +synonym: "LPA1 receptor binding" EXACT [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031756 +name: Edg-3 sphingosine 1-phosphate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-3 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] +synonym: "Edg-3 sphingosine 1-phosphate receptor ligand" NARROW [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031757 +name: Edg-4 lysophosphatidic acid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] +synonym: "Edg-4 lysophosphatidic acid receptor ligand" NARROW [] +synonym: "LPA2 receptor binding" EXACT [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031758 +name: Edg-5 sphingosine 1-phosphate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-5 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] +synonym: "Edg-5 sphingosine 1-phosphate receptor ligand" NARROW [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031759 +name: Edg-6 sphingosine 1-phosphate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-6 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] +synonym: "Edg-6 sphingosine 1-phosphate receptor ligand" NARROW [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031760 +name: Edg-7 lysophosphatidic acid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Edg-7 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] +synonym: "Edg-7 lysophosphatidic acid receptor ligand" NARROW [] +synonym: "LPA3 receptor binding" EXACT [] +is_a: GO:0031753 ! endothelial differentiation G protein-coupled receptor binding + +[Term] +id: GO:0031761 +name: fMet-Leu-Phe receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a fMet-Leu-Phe receptor." [GOC:mah, GOC:nln] +synonym: "fMet-Leu-Phe receptor ligand" NARROW [] +synonym: "N-formyl peptide receptor binding" EXACT [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031762 +name: follicle-stimulating hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a follicle-stimulating hormone receptor." [GOC:mah, GOC:nln] +synonym: "follicle stimulating hormone receptor binding" EXACT [] +synonym: "follicle stimulating hormone receptor ligand" NARROW [] +synonym: "FSH receptor binding" EXACT [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031763 +name: galanin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a galanin receptor." [GOC:mah, GOC:nln] +synonym: "galanin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031764 +name: type 1 galanin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 galanin receptor." [GOC:mah, GOC:nln] +synonym: "type 1 galanin receptor ligand" NARROW [] +is_a: GO:0031763 ! galanin receptor binding + +[Term] +id: GO:0031765 +name: type 2 galanin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 galanin receptor." [GOC:mah, GOC:nln] +synonym: "type 2 galanin receptor ligand" NARROW [] +is_a: GO:0031763 ! galanin receptor binding + +[Term] +id: GO:0031766 +name: type 3 galanin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 3 galanin receptor." [GOC:mah, GOC:nln] +synonym: "type 3 galanin receptor ligand" NARROW [] +is_a: GO:0031763 ! galanin receptor binding + +[Term] +id: GO:0031767 +name: gastric inhibitory polypeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a gastric inhibitory polypeptide receptor." [GOC:mah, GOC:nln] +synonym: "gastric inhibitory polypeptide receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031768 +name: ghrelin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ghrelin receptor." [GOC:mah, GOC:nln] +synonym: "ghrelin receptor ligand" NARROW [] +synonym: "type 1 growth hormone secretagogue GH-releasing peptide receptor binding" EXACT [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031769 +name: glucagon receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a glucagon receptor." [GOC:mah, GOC:nln] +synonym: "glucagon receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031770 +name: growth hormone-releasing hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a growth hormone-releasing hormone receptor." [GOC:mah, GOC:nln] +synonym: "growth hormone-releasing hormone receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031771 +name: type 1 hypocretin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 hypocretin receptor." [GOC:mah, GOC:nln] +synonym: "type 1 hypocretin receptor ligand" NARROW [] +synonym: "type 1 orexin receptor binding" EXACT [] +is_a: GO:0042324 ! hypocretin receptor binding + +[Term] +id: GO:0031772 +name: type 2 hypocretin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 hypocretin receptor." [GOC:mah, GOC:nln] +synonym: "type 2 hypocretin receptor ligand" NARROW [] +synonym: "type 2 orexin receptor binding" EXACT [] +is_a: GO:0042324 ! hypocretin receptor binding + +[Term] +id: GO:0031773 +name: kisspeptin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kisspeptin receptor." [GOC:mah, GOC:nln] +synonym: "G-protein coupled receptor 54 binding" EXACT [] +synonym: "hOT7T175 receptor binding" EXACT [] +synonym: "hypogonadotropin-1 receptor binding" EXACT [] +synonym: "KiSS-1 receptor binding" EXACT [] +synonym: "kisspeptin receptor ligand" NARROW [] +synonym: "metastin receptor binding" EXACT [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031774 +name: leukotriene receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a leukotriene receptor." [GOC:mah, GOC:nln] +synonym: "leukotriene receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031775 +name: lutropin-choriogonadotropic hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor." [GOC:mah, GOC:nln] +synonym: "lutropin-choriogonadotropic hormone receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031776 +name: melanin-concentrating hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] +synonym: "melanin-concentrating hormone receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031777 +name: type 1 melanin-concentrating hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] +synonym: "type 1 melanin-concentrating hormone receptor ligand" NARROW [] +is_a: GO:0031776 ! melanin-concentrating hormone receptor binding + +[Term] +id: GO:0031778 +name: type 2 melanin-concentrating hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] +synonym: "type 2 melanin-concentrating hormone receptor ligand" NARROW [] +is_a: GO:0031776 ! melanin-concentrating hormone receptor binding + +[Term] +id: GO:0031779 +name: melanocortin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a melanocortin receptor." [GOC:mah, GOC:nln] +synonym: "melanocortin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031780 +name: corticotropin hormone receptor binding +namespace: molecular_function +alt_id: GO:0071856 +def: "Interacting selectively and non-covalently with a corticotropin hormone receptor." [GOC:dph, GOC:mah, GOC:nln] +synonym: "ACTH receptor binding" EXACT [] +synonym: "adrenocorticotropic hormone receptor ligand" NARROW [] +synonym: "adrenocorticotropin hormone receptor binding" EXACT [GOC:dph, GOC:tb] +synonym: "adrenocorticotropin receptor binding" EXACT [GOC:dph] +synonym: "corticotropin receptor binding" EXACT [GOC:bf] +is_a: GO:0031779 ! melanocortin receptor binding + +[Term] +id: GO:0031781 +name: type 3 melanocortin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 3 melanocortin receptor." [GOC:mah, GOC:nln] +synonym: "type 3 melanocortin receptor ligand" NARROW [] +is_a: GO:0031779 ! melanocortin receptor binding + +[Term] +id: GO:0031782 +name: type 4 melanocortin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 melanocortin receptor." [GOC:mah, GOC:nln] +synonym: "type 4 melanocortin receptor ligand" NARROW [] +is_a: GO:0031779 ! melanocortin receptor binding + +[Term] +id: GO:0031783 +name: type 5 melanocortin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5 melanocortin receptor." [GOC:mah, GOC:nln] +synonym: "type 5 melanocortin receptor ligand" NARROW [] +is_a: GO:0031779 ! melanocortin receptor binding + +[Term] +id: GO:0031784 +name: melatonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a melatonin receptor." [GOC:mah, GOC:nln] +synonym: "melatonin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031785 +name: type 1A melatonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1A melatonin receptor." [GOC:mah, GOC:nln] +synonym: "type 1A melatonin receptor ligand" NARROW [] +is_a: GO:0031784 ! melatonin receptor binding + +[Term] +id: GO:0031786 +name: type 1B melatonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1B melatonin receptor." [GOC:mah, GOC:nln] +synonym: "type 1B melatonin receptor ligand" NARROW [] +is_a: GO:0031784 ! melatonin receptor binding + +[Term] +id: GO:0031787 +name: H9 melatonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a H9 melatonin receptor." [GOC:mah, GOC:nln] +synonym: "H9 melatonin receptor ligand" NARROW [] +is_a: GO:0031784 ! melatonin receptor binding + +[Term] +id: GO:0031788 +name: motilin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a motilin receptor." [GOC:mah, GOC:nln] +synonym: "motilin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031789 +name: G protein-coupled acetylcholine receptor binding +namespace: molecular_function +alt_id: GO:0031790 +alt_id: GO:0031791 +alt_id: GO:0031792 +alt_id: GO:0031793 +alt_id: GO:0031794 +def: "Interacting selectively and non-covalently with a G protein-coupled acetylcholine receptor." [GOC:bf, GOC:mah, GOC:nln] +synonym: "G-protein coupled acetylcholine receptor binding" EXACT [] +synonym: "M1 muscarinic acetylcholine receptor binding" NARROW [] +synonym: "M1 muscarinic acetylcholine receptor ligand" NARROW [] +synonym: "M2 muscarinic acetylcholine receptor binding" NARROW [] +synonym: "M2 muscarinic acetylcholine receptor ligand" NARROW [] +synonym: "M3 muscarinic acetylcholine receptor binding" NARROW [] +synonym: "M3 muscarinic acetylcholine receptor ligand" NARROW [] +synonym: "M4 muscarinic acetylcholine receptor binding" NARROW [] +synonym: "M4 muscarinic acetylcholine receptor ligand" NARROW [] +synonym: "M5 muscarinic acetylcholine receptor binding" NARROW [] +synonym: "M5 muscarinic acetylcholine receptor ligand" NARROW [] +synonym: "muscarinic acetylcholine receptor binding" EXACT [GOC:bf] +synonym: "muscarinic acetylcholine receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031795 +name: G protein-coupled GABA receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G protein-coupled (metabotropic) GABA receptor." [GOC:mah, GOC:nln] +synonym: "G-protein coupled GABA receptor binding" EXACT [] +synonym: "GABAB receptor binding" EXACT [] +synonym: "metabotropic GABA receptor binding" EXACT [GOC:bf] +synonym: "metabotropic GABA receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding +is_a: GO:0050811 ! GABA receptor binding + +[Term] +id: GO:0031796 +name: type 1 metabotropic GABA receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 metabotropic GABA receptor." [GOC:mah, GOC:nln] +synonym: "type 1 metabotropic GABA receptor ligand" NARROW [] +is_a: GO:0031795 ! G protein-coupled GABA receptor binding + +[Term] +id: GO:0031797 +name: type 2 metabotropic GABA receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 metabotropic GABA receptor." [GOC:mah, GOC:nln] +synonym: "type 2 metabotropic GABA receptor ligand" NARROW [] +is_a: GO:0031795 ! G protein-coupled GABA receptor binding + +[Term] +id: GO:0031798 +name: type 1 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 1 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031799 +name: type 2 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 2 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031800 +name: type 3 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 3 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 3 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031801 +name: type 4 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 4 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031802 +name: type 5 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 5 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031803 +name: type 6 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 6 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 6 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031804 +name: type 7 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 7 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031805 +name: type 8 metabotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 8 metabotropic glutamate receptor." [GOC:mah, GOC:nln] +synonym: "type 8 metabotropic glutamate receptor ligand" NARROW [] +is_a: GO:0035256 ! G protein-coupled glutamate receptor binding + +[Term] +id: GO:0031806 +name: G protein-coupled histamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G protein-coupled (metabotropic) histamine receptor." [GOC:mah, GOC:nln, PMID:12679144] +synonym: "G-protein coupled histamine receptor binding" EXACT [] +synonym: "metabotropic histamine receptor binding" EXACT [GOC:bf] +synonym: "metabotropic histamine receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031807 +name: H1 histamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a H1 histamine receptor." [GOC:mah, GOC:nln] +synonym: "H1 histamine receptor ligand" NARROW [] +is_a: GO:0031806 ! G protein-coupled histamine receptor binding + +[Term] +id: GO:0031808 +name: H2 histamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a H2 histamine receptor." [GOC:mah, GOC:nln] +synonym: "H2 histamine receptor ligand" NARROW [] +is_a: GO:0031806 ! G protein-coupled histamine receptor binding + +[Term] +id: GO:0031809 +name: H3 histamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a H3 histamine receptor." [GOC:mah, GOC:nln] +synonym: "H3 histamine receptor ligand" NARROW [] +is_a: GO:0031806 ! G protein-coupled histamine receptor binding + +[Term] +id: GO:0031810 +name: H4 histamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a H4 histamine receptor." [GOC:mah, GOC:nln] +synonym: "H4 histamine receptor ligand" NARROW [] +is_a: GO:0031806 ! G protein-coupled histamine receptor binding + +[Term] +id: GO:0031811 +name: G protein-coupled nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G protein-coupled (metabotropic) nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "G-protein coupled nucleotide receptor binding" EXACT [] +synonym: "metabotropic nucleotide receptor binding" EXACT [GOC:bf] +synonym: "metabotropic nucleotide receptor ligand" NARROW [] +synonym: "P2Y receptor binding" EXACT [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031812 +name: P2Y1 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y1 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y1 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031813 +name: P2Y2 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y2 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y2 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031814 +name: P2Y4 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y4 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y4 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031815 +name: P2Y5 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y5 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y5 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031816 +name: P2Y6 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y6 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y6 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031817 +name: P2Y8 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y8 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y8 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031818 +name: P2Y9 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y9 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y9 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031819 +name: P2Y10 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y10 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y10 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031820 +name: P2Y11 nucleotide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a P2Y11 nucleotide receptor." [GOC:mah, GOC:nln] +synonym: "P2Y11 nucleotide receptor ligand" NARROW [] +is_a: GO:0031811 ! G protein-coupled nucleotide receptor binding + +[Term] +id: GO:0031821 +name: G protein-coupled serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a metabotropic serotonin receptor." [GOC:mah, GOC:nln] +synonym: "G-protein coupled serotonin receptor binding" EXACT [] +synonym: "metabotropic 5-hydroxytryptamine receptor binding" EXACT [] +synonym: "metabotropic serotonin receptor binding" EXACT [GOC:bf] +synonym: "metabotropic serotonin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031822 +name: type 1B serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1B serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 1B receptor binding" EXACT [] +synonym: "type 1B serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031823 +name: type 1D serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1D serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 1D receptor binding" EXACT [] +synonym: "type 1D serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031824 +name: type 1E serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1E serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 1E receptor binding" EXACT [] +synonym: "type 1E serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031825 +name: type 1F serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1F serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 1F receptor binding" EXACT [] +synonym: "type 1F serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031826 +name: type 2A serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2A serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 2A receptor binding" EXACT [] +synonym: "type 2A serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031827 +name: type 2B serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2B serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 2B receptor binding" EXACT [] +synonym: "type 2B serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031828 +name: type 2C serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2C serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 2C receptor binding" EXACT [] +synonym: "type 2C serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031829 +name: type 4 serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 4 receptor binding" EXACT [] +synonym: "type 4 serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031830 +name: type 5A serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5A serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 5A receptor binding" EXACT [] +synonym: "type 5A serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031831 +name: type 5B serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5B serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 5B receptor binding" EXACT [] +synonym: "type 5B serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031832 +name: type 6 serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 6 serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 6 receptor binding" EXACT [] +synonym: "type 6 serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031833 +name: type 7 serotonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 7 serotonin receptor." [GOC:mah, GOC:nln] +synonym: "5-hydroxytryptamine 7 receptor binding" EXACT [] +synonym: "type 7 serotonin receptor ligand" NARROW [] +is_a: GO:0031821 ! G protein-coupled serotonin receptor binding + +[Term] +id: GO:0031834 +name: neurokinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neurokinin receptor." [GOC:mah, GOC:nln] +synonym: "neurokinin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031835 +name: substance P receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a substance P receptor." [GOC:mah, GOC:nln] +synonym: "neurokinin-1 receptor binding" EXACT [] +synonym: "substance P receptor ligand" NARROW [] +is_a: GO:0031834 ! neurokinin receptor binding + +[Term] +id: GO:0031836 +name: neuromedin K receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuromedin K receptor." [GOC:mah, GOC:nln] +synonym: "neurokinin-B receptor binding" EXACT [] +synonym: "neuromedin K receptor ligand" NARROW [] +is_a: GO:0031834 ! neurokinin receptor binding + +[Term] +id: GO:0031837 +name: substance K receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a substance K receptor." [GOC:mah, GOC:nln] +synonym: "neurokinin-A receptor binding" EXACT [] +synonym: "substance K receptor ligand" NARROW [] +is_a: GO:0031834 ! neurokinin receptor binding + +[Term] +id: GO:0031838 +name: haptoglobin-hemoglobin complex +namespace: cellular_component +def: "A protein complex formed by the stable binding of a haptoglobin to hemoglobin." [GOC:mah] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0031839 +name: type 1 neuromedin U receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 neuromedin U receptor." [GOC:mah, GOC:nln] +synonym: "type 1 neuromedin U receptor ligand" NARROW [] +is_a: GO:0042922 ! neuromedin U receptor binding + +[Term] +id: GO:0031840 +name: type 2 neuromedin U receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 neuromedin U receptor." [GOC:mah, GOC:nln] +synonym: "type 2 neuromedin U receptor ligand" NARROW [] +is_a: GO:0042922 ! neuromedin U receptor binding + +[Term] +id: GO:0031841 +name: neuropeptide Y receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuropeptide Y receptor." [GOC:mah, GOC:nln] +synonym: "neuropeptide Y receptor ligand" NARROW [] +synonym: "NPY receptor binding" EXACT [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031842 +name: type 1 neuropeptide Y receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 neuropeptide Y receptor." [GOC:mah, GOC:nln] +synonym: "type 1 neuropeptide Y receptor ligand" NARROW [] +is_a: GO:0031841 ! neuropeptide Y receptor binding + +[Term] +id: GO:0031843 +name: type 2 neuropeptide Y receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 neuropeptide Y receptor." [GOC:mah, GOC:nln] +synonym: "type 2 neuropeptide Y receptor ligand" NARROW [] +is_a: GO:0031841 ! neuropeptide Y receptor binding + +[Term] +id: GO:0031844 +name: type 4 neuropeptide Y receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 neuropeptide Y receptor." [GOC:mah, GOC:nln] +synonym: "pancreatic polypeptide receptor binding" EXACT [] +synonym: "type 4 neuropeptide Y receptor ligand" NARROW [] +is_a: GO:0031841 ! neuropeptide Y receptor binding + +[Term] +id: GO:0031845 +name: type 5 neuropeptide Y receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5 neuropeptide Y receptor." [GOC:mah, GOC:nln] +synonym: "type 5 neuropeptide Y receptor ligand" NARROW [] +is_a: GO:0031841 ! neuropeptide Y receptor binding + +[Term] +id: GO:0031846 +name: neurotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neurotensin receptor." [GOC:mah, GOC:nln] +synonym: "neurotensin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031847 +name: type 1 neurotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 neurotensin receptor." [GOC:mah, GOC:nln] +synonym: "type 1 neurotensin receptor ligand" NARROW [] +is_a: GO:0031846 ! neurotensin receptor binding + +[Term] +id: GO:0031848 +name: protection from non-homologous end joining at telomere +namespace: biological_process +def: "A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse." [GOC:mah] +synonym: "protection from NHEJ-mediated telomere fusion" EXACT [] +is_a: GO:0043247 ! telomere maintenance in response to DNA damage +relationship: part_of GO:0016233 ! telomere capping + +[Term] +id: GO:0031849 +name: olfactory receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an olfactory receptor." [GOC:mah, GOC:nln] +synonym: "olfactory receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031850 +name: delta-type opioid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a delta-type opioid receptor." [GOC:mah, GOC:nln] +synonym: "delta-type opioid receptor ligand" NARROW [] +synonym: "enkephalin receptor binding" RELATED [GOC:sl] +is_a: GO:0031628 ! opioid receptor binding + +[Term] +id: GO:0031851 +name: kappa-type opioid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kappa-type opioid receptor." [GOC:mah, GOC:nln] +synonym: "dynorphin receptor binding" RELATED [] +synonym: "kappa-type opioid receptor ligand" NARROW [GOC:sl] +is_a: GO:0031628 ! opioid receptor binding + +[Term] +id: GO:0031852 +name: mu-type opioid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mu-type opioid receptor." [GOC:mah, GOC:nln, GOC:sl] +synonym: "morphine receptor binding" RELATED [GOC:sl] +synonym: "mu-type opioid receptor ligand" NARROW [] +is_a: GO:0031628 ! opioid receptor binding + +[Term] +id: GO:0031853 +name: nociceptin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nociceptin receptor." [GOC:mah, GOC:nln] +synonym: "nociceptin receptor ligand" NARROW [] +is_a: GO:0031628 ! opioid receptor binding + +[Term] +id: GO:0031854 +name: orexigenic neuropeptide QRFP receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an orexigenic neuropeptide QRFP receptor." [GOC:mah, GOC:nln] +synonym: "orexigenic neuropeptide QRFP receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031855 +name: oxytocin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an oxytocin receptor." [GOC:mah, GOC:nln] +synonym: "oxytocin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031856 +name: parathyroid hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a parathyroid hormone receptor." [GOC:mah, GOC:nln] +synonym: "parathyroid hormone receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031857 +name: type 1 parathyroid hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 parathyroid hormone receptor." [GOC:mah, GOC:nln] +synonym: "type 1 parathyroid hormone receptor ligand" NARROW [] +is_a: GO:0031856 ! parathyroid hormone receptor binding + +[Term] +id: GO:0031858 +name: pituitary adenylate cyclase-activating polypeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor." [GOC:mah, GOC:nln] +synonym: "PACAP receptor binding" EXACT [] +synonym: "pituitary adenylate cyclase activating peptide receptor binding" EXACT [GOC:dph, GOC:tb] +synonym: "pituitary adenylate cyclase-activating peptide receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031859 +name: platelet activating factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a platelet activating factor receptor." [GOC:mah, GOC:nln] +synonym: "platelet activating factor receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031860 +name: telomeric 3' overhang formation +namespace: biological_process +def: "The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans." [PMID:16096639] +synonym: "telomere 3'-end processing" EXACT [GOC:mah, GOC:vw] +synonym: "telomere end processing" RELATED [GOC:mah, GOC:vw] +is_a: GO:0022616 ! DNA strand elongation +relationship: part_of GO:0016233 ! telomere capping + +[Term] +id: GO:0031861 +name: prolactin-releasing peptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prolactin-releasing peptide receptor." [GOC:mah, GOC:nln] +synonym: "prolactin-releasing peptide receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031862 +name: prostanoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prostanoid receptor." [GOC:mah, GOC:nln] +synonym: "prostanoid receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031863 +name: prostaglandin D2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prostaglandin D2 receptor." [GOC:mah, GOC:nln] +synonym: "prostaglandin D2 receptor ligand" NARROW [] +synonym: "prostanoid DP receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031864 +name: EP1 subtype prostaglandin E2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] +synonym: "EP1 subtype prostaglandin E2 receptor ligand" NARROW [] +synonym: "prostanoid EP1 receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031865 +name: EP2 subtype prostaglandin E2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an EP2 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] +synonym: "EP2 subtype prostaglandin E2 receptor ligand" NARROW [] +synonym: "prostanoid EP2 receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031866 +name: EP3 subtype prostaglandin E2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an EP3 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] +synonym: "EP3 subtype prostaglandin E2 receptor ligand" NARROW [] +synonym: "prostanoid EP3 receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031867 +name: EP4 subtype prostaglandin E2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an EP4 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] +synonym: "EP4 subtype prostaglandin E2 receptor ligand" NARROW [] +synonym: "prostanoid EP4 receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031868 +name: prostaglandin F2-alpha receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prostaglandin F2-alpha receptor." [GOC:mah, GOC:nln] +synonym: "prostaglandin F2-alpha receptor ligand" NARROW [] +synonym: "prostanoid FP receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031869 +name: prostacyclin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prostacyclin receptor." [GOC:mah, GOC:nln] +synonym: "prostacyclin receptor ligand" NARROW [] +synonym: "prostanoid IP receptor binding" EXACT [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031870 +name: thromboxane A2 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a thromboxane A2 receptor." [GOC:mah, GOC:nln] +synonym: "prostanoid TP receptor binding" EXACT [] +synonym: "thromboxane A2 receptor ligand" NARROW [] +is_a: GO:0031862 ! prostanoid receptor binding + +[Term] +id: GO:0031871 +name: proteinase activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proteinase activated receptor." [GOC:mah, GOC:nln] +synonym: "proteinase activated receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031872 +name: type 1 proteinase activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 proteinase activated receptor." [GOC:mah, GOC:nln] +synonym: "thrombin receptor binding" EXACT [] +synonym: "type 1 proteinase activated receptor ligand" NARROW [] +is_a: GO:0031871 ! proteinase activated receptor binding + +[Term] +id: GO:0031873 +name: type 2 proteinase activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 proteinase activated receptor." [GOC:mah, GOC:nln] +synonym: "type 2 proteinase activated receptor ligand" NARROW [] +is_a: GO:0031871 ! proteinase activated receptor binding + +[Term] +id: GO:0031874 +name: type 3 proteinase activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 3 proteinase activated receptor." [GOC:mah, GOC:nln] +synonym: "type 3 proteinase activated receptor ligand" NARROW [] +is_a: GO:0031871 ! proteinase activated receptor binding + +[Term] +id: GO:0031875 +name: type 4 proteinase activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 proteinase activated receptor." [GOC:mah, GOC:nln] +synonym: "type 4 proteinase activated receptor ligand" NARROW [] +is_a: GO:0031871 ! proteinase activated receptor binding + +[Term] +id: GO:0031876 +name: secretin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a secretin receptor." [GOC:mah, GOC:nln] +synonym: "secretin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031877 +name: somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "somatostatin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031878 +name: type 1 somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "type 1 somatostatin receptor ligand" NARROW [] +is_a: GO:0031877 ! somatostatin receptor binding + +[Term] +id: GO:0031879 +name: type 2 somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "type 2 somatostatin receptor ligand" NARROW [] +is_a: GO:0031877 ! somatostatin receptor binding + +[Term] +id: GO:0031880 +name: type 3 somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 3 somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "type 3 somatostatin receptor ligand" NARROW [] +is_a: GO:0031877 ! somatostatin receptor binding + +[Term] +id: GO:0031881 +name: type 4 somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 4 somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "type 4 somatostatin receptor ligand" NARROW [] +is_a: GO:0031877 ! somatostatin receptor binding + +[Term] +id: GO:0031882 +name: type 5 somatostatin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 5 somatostatin receptor." [GOC:mah, GOC:nln] +synonym: "type 5 somatostatin receptor ligand" NARROW [] +is_a: GO:0031877 ! somatostatin receptor binding + +[Term] +id: GO:0031883 +name: taste receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a taste receptor." [GOC:mah, GOC:nln] +synonym: "taste receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031884 +name: type 1 member 1 taste receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 member 1 taste receptor." [GOC:mah, GOC:nln] +synonym: "type 1 member 1 taste receptor ligand" NARROW [] +is_a: GO:0031883 ! taste receptor binding + +[Term] +id: GO:0031885 +name: type 1 member 2 taste receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 member 2 taste receptor." [GOC:mah, GOC:nln] +synonym: "type 1 member 2 taste receptor ligand" NARROW [] +is_a: GO:0031883 ! taste receptor binding + +[Term] +id: GO:0031886 +name: type 1 member 3 taste receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 member 3 taste receptor." [GOC:mah, GOC:nln] +synonym: "sweet taste receptor binding" EXACT [] +synonym: "type 1 member 3 taste receptor ligand" NARROW [] +is_a: GO:0031883 ! taste receptor binding + +[Term] +id: GO:0031887 +name: lipid droplet transport along microtubule +namespace: biological_process +def: "The directed movement of a lipid droplet along a microtubule, mediated by motor proteins." [PMID:9491895] +synonym: "adiposome transport along microtubule" EXACT [] +synonym: "lipid body transport along microtubule" EXACT [] +synonym: "lipid particle transport along microtubule" EXACT [] +is_a: GO:0072384 ! organelle transport along microtubule + +[Term] +id: GO:0031889 +name: urotensin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a urotensin receptor." [GOC:mah, GOC:nln] +synonym: "urotensin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031890 +name: vasoactive intestinal polypeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] +synonym: "vasoactive intestinal polypeptide receptor ligand" NARROW [] +synonym: "VIP receptor binding" EXACT [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0031891 +name: type 1 vasoactive intestinal polypeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] +synonym: "type 1 vasoactive intestinal polypeptide receptor ligand" NARROW [] +synonym: "type 2 PACAP receptor binding" EXACT [] +is_a: GO:0031890 ! vasoactive intestinal polypeptide receptor binding + +[Term] +id: GO:0031892 +name: type 2 vasoactive intestinal polypeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] +synonym: "type 2 vasoactive intestinal polypeptide receptor ligand" NARROW [] +synonym: "type 3 PACAP receptor binding" EXACT [] +is_a: GO:0031890 ! vasoactive intestinal polypeptide receptor binding + +[Term] +id: GO:0031893 +name: vasopressin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a vasopressin receptor." [GOC:mah, GOC:nln] +synonym: "vasopressin receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0031894 +name: V1A vasopressin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a V1A vasopressin receptor." [GOC:mah, GOC:nln] +synonym: "V1A vasopressin receptor ligand" NARROW [] +is_a: GO:0031893 ! vasopressin receptor binding + +[Term] +id: GO:0031895 +name: V1B vasopressin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a V1B vasopressin receptor." [GOC:mah, GOC:nln] +synonym: "V1B vasopressin receptor ligand" NARROW [] +is_a: GO:0031893 ! vasopressin receptor binding + +[Term] +id: GO:0031896 +name: V2 vasopressin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a V2 vasopressin receptor." [GOC:mah, GOC:nln] +synonym: "V2 vasopressin receptor ligand" NARROW [] +is_a: GO:0031893 ! vasopressin receptor binding + +[Term] +id: GO:0031897 +name: Tic complex +namespace: cellular_component +def: "The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane." [PMID:12180471, PMID:12393016] +synonym: "chloroplast inner membrane translocase complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009706 ! chloroplast inner membrane + +[Term] +id: GO:0031898 +name: chromoplast envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:pz] +is_a: GO:0009526 ! plastid envelope +relationship: part_of GO:0009509 ! chromoplast + +[Term] +id: GO:0031899 +name: chromoplast inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma." [GOC:pz] +is_a: GO:0009528 ! plastid inner membrane +is_a: GO:0046862 ! chromoplast membrane + +[Term] +id: GO:0031900 +name: chromoplast outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope." [GOC:pz] +is_a: GO:0009527 ! plastid outer membrane +is_a: GO:0046862 ! chromoplast membrane + +[Term] +id: GO:0031901 +name: early endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an early endosome." [GOC:pz] +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0005769 ! early endosome + +[Term] +id: GO:0031902 +name: late endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a late endosome." [GOC:pz] +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0005770 ! late endosome + +[Term] +id: GO:0031903 +name: microbody membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a microbody." [GOC:mah] +is_a: GO:0042579 ! microbody +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane + +[Term] +id: GO:0031904 +name: endosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an endosome." [GOC:mah] +xref: NIF_Subcellular:sao1547508851 +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0005768 ! endosome + +[Term] +id: GO:0031905 +name: early endosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an early endosome." [GOC:mah] +is_a: GO:0031904 ! endosome lumen +relationship: part_of GO:0005769 ! early endosome + +[Term] +id: GO:0031906 +name: late endosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a late endosome." [GOC:mah] +is_a: GO:0031904 ! endosome lumen +relationship: part_of GO:0005770 ! late endosome + +[Term] +id: GO:0031907 +name: microbody lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of a microbody." [GOC:mah] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0042579 ! microbody + +[Term] +id: GO:0031908 +name: glyoxysomal lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of a glyoxysome." [GOC:mah] +is_a: GO:0005782 ! peroxisomal matrix + +[Term] +id: GO:0031910 +name: cytostome +namespace: cellular_component +def: "Stable, specialized structure for the ingestion of food by the cell into phagosomes." [PMID:10503189] +xref: Wikipedia:Cytostome +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0031911 +name: cytoproct +namespace: cellular_component +def: "Stable, specialized structure for extrusion of waste by the cell into the surrounding medium." [PMID:10503189] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0031912 +name: oral apparatus +namespace: cellular_component +def: "Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems." [PMID:10503189] +comment: Note that this term refers to a subcellular structure characteristic of ciliate protozoans, and should not be confused with oral anatomical structures of multicellular animals. +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0031913 +name: contractile vacuole pore +namespace: cellular_component +def: "Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium." [PMID:10503189] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0031164 ! contractile vacuolar membrane + +[Term] +id: GO:0031914 +name: negative regulation of synaptic plasticity +namespace: biological_process +def: "A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah] +synonym: "down regulation of synaptic plasticity" EXACT [] +synonym: "down-regulation of synaptic plasticity" EXACT [] +synonym: "downregulation of synaptic plasticity" EXACT [] +synonym: "inhibition of synaptic plasticity" NARROW [] +is_a: GO:0048167 ! regulation of synaptic plasticity + +[Term] +id: GO:0031915 +name: positive regulation of synaptic plasticity +namespace: biological_process +def: "A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah] +synonym: "activation of synaptic plasticity" NARROW [] +synonym: "stimulation of synaptic plasticity" NARROW [] +synonym: "up regulation of synaptic plasticity" EXACT [] +synonym: "up-regulation of synaptic plasticity" EXACT [] +synonym: "upregulation of synaptic plasticity" EXACT [] +is_a: GO:0048167 ! regulation of synaptic plasticity + +[Term] +id: GO:0031916 +name: regulation of synaptic metaplasticity +namespace: biological_process +def: "A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] +is_a: GO:0048167 ! regulation of synaptic plasticity + +[Term] +id: GO:0031917 +name: negative regulation of synaptic metaplasticity +namespace: biological_process +def: "A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] +synonym: "down regulation of synaptic metaplasticity" EXACT [] +synonym: "down-regulation of synaptic metaplasticity" EXACT [] +synonym: "downregulation of synaptic metaplasticity" EXACT [] +synonym: "inhibition of synaptic metaplasticity" NARROW [] +is_a: GO:0031914 ! negative regulation of synaptic plasticity +is_a: GO:0031916 ! regulation of synaptic metaplasticity + +[Term] +id: GO:0031918 +name: positive regulation of synaptic metaplasticity +namespace: biological_process +def: "A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] +synonym: "activation of synaptic metaplasticity" NARROW [] +synonym: "stimulation of synaptic metaplasticity" NARROW [] +synonym: "up regulation of synaptic metaplasticity" EXACT [] +synonym: "up-regulation of synaptic metaplasticity" EXACT [] +synonym: "upregulation of synaptic metaplasticity" EXACT [] +is_a: GO:0031915 ! positive regulation of synaptic plasticity +is_a: GO:0031916 ! regulation of synaptic metaplasticity + +[Term] +id: GO:0031919 +name: vitamin B6 transport +namespace: biological_process +def: "The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0031920 +name: pyridoxal transport +namespace: biological_process +def: "The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0031919 ! vitamin B6 transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0031921 +name: pyridoxal phosphate transport +namespace: biological_process +def: "The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6." [GOC:mah] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0031919 ! vitamin B6 transport +is_a: GO:0051182 ! coenzyme transport + +[Term] +id: GO:0031922 +name: pyridoxamine transport +namespace: biological_process +def: "The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0031919 ! vitamin B6 transport + +[Term] +id: GO:0031923 +name: pyridoxine transport +namespace: biological_process +def: "The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0031919 ! vitamin B6 transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0031924 +name: vitamin B6 transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other." [GOC:mah] +synonym: "vitamin B6 transporter activity" RELATED [] +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0031919 ! vitamin B6 transport + +[Term] +id: GO:0031925 +name: pyridoxal transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +synonym: "pyridoxal transporter activity" BROAD [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0031924 ! vitamin B6 transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:1903090 ! pyridoxal transmembrane transport + +[Term] +id: GO:0031926 +name: pyridoxal phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6." [GOC:mah] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0031924 ! vitamin B6 transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity + +[Term] +id: GO:0031927 +name: pyridoxamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0031924 ! vitamin B6 transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:1903091 ! pyridoxamine transmembrane transport + +[Term] +id: GO:0031928 +name: pyridoxine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] +synonym: "pyridoxine transporter activity" BROAD [] +is_a: GO:0031924 ! vitamin B6 transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:1903092 ! pyridoxine transmembrane transport + +[Term] +id: GO:0031929 +name: TOR signaling +namespace: biological_process +def: "A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors." [PMID:12372295] +comment: Note that this term should not be confused with 'torso signaling pathway ; GO:0008293', although torso is abbreviated 'tor'. +synonym: "target of rapamycin signaling pathway" EXACT [] +synonym: "target of rapamycin signalling pathway" EXACT [] +synonym: "TOR signal transduction" EXACT [GOC:signaling] +synonym: "TOR signaling cascade" RELATED [GOC:signaling] +synonym: "TOR signaling pathway" EXACT [] +synonym: "TOR signalling pathway" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0031930 +name: mitochondria-nucleus signaling pathway +namespace: biological_process +def: "A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function." [GOC:jh, PMID:15068799] +synonym: "mitochondria-nucleus signal transduction" EXACT [GOC:signaling] +synonym: "mitochondrial signaling pathway" EXACT [] +synonym: "mitochondrial signalling pathway" EXACT [] +synonym: "retrograde response" EXACT [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0031931 +name: TORC1 complex +namespace: cellular_component +def: "A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p." [GOC:jh, PMID:15780592, PMID:16469695, PMID:21548787] +synonym: "dTOR/dRaptor complex" NARROW [PMID:17183368] +synonym: "dTORC1" NARROW [PMID:17183368] +synonym: "mTORC1" NARROW [PMID:18765678, PMID:21548787] +synonym: "nutrient sensitive complex" EXACT [] +synonym: "rapamycin and nutrient-sensitive TOR complex" EXACT [PMID:21548787] +synonym: "TOR complex 1" EXACT [] +synonym: "TORC 1 complex" EXACT [] +synonym: "TORC1" EXACT [PMID:21548787] +xref: Wikipedia:MTORC1 +is_a: GO:0038201 ! TOR complex + +[Term] +id: GO:0031932 +name: TORC2 complex +namespace: cellular_component +def: "A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p." [GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787] +synonym: "mTORC2" NARROW [PMID:20496258, PMID:21548787] +synonym: "rapamycin and nutrient-insensitive TOR complex" EXACT [PMID:21548787] +synonym: "TOR complex 2" EXACT [] +synonym: "TORC 2 complex" EXACT [] +synonym: "TORC2" EXACT [PMID:21548787] +xref: Wikipedia:MTORC1 +is_a: GO:0038201 ! TOR complex + +[Term] +id: GO:0031933 +name: obsolete telomeric heterochromatin +namespace: cellular_component +def: "OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres." [GOC:mah] +comment: This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently. +synonym: "telomeric chromatin" BROAD [GOC:pr] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19086 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0031934 +name: mating-type region heterochromatin +namespace: cellular_component +def: "Heterochromatic regions of the chromosome found at silenced mating-type loci." [GOC:mah] +is_a: GO:0000792 ! heterochromatin + +[Term] +id: GO:0031935 +name: regulation of chromatin silencing +namespace: biological_process +def: "Any process that affects the rate, extent or location of chromatin silencing." [GOC:mah] +synonym: "regulation of heterochromatic silencing" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0060968 ! regulation of gene silencing +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006342 ! chromatin silencing +relationship: regulates GO:0006342 ! chromatin silencing + +[Term] +id: GO:0031936 +name: negative regulation of chromatin silencing +namespace: biological_process +alt_id: GO:0006345 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing." [GOC:mah] +synonym: "down regulation of chromatin silencing" EXACT [] +synonym: "down-regulation of chromatin silencing" EXACT [] +synonym: "downregulation of chromatin silencing" EXACT [] +synonym: "inhibition of chromatin silencing" NARROW [] +synonym: "loss of chromatin silencing" EXACT [] +synonym: "negative regulation of heterochromatic silencing" EXACT [] +is_a: GO:0031935 ! regulation of chromatin silencing +is_a: GO:0045815 ! positive regulation of gene expression, epigenetic +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:0060969 ! negative regulation of gene silencing +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006342 ! chromatin silencing +relationship: negatively_regulates GO:0006342 ! chromatin silencing + +[Term] +id: GO:0031937 +name: positive regulation of chromatin silencing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromatin silencing." [GOC:mah] +synonym: "activation of chromatin silencing" NARROW [] +synonym: "positive regulation of heterochromatic silencing" EXACT [] +synonym: "stimulation of chromatin silencing" NARROW [] +synonym: "up regulation of chromatin silencing" EXACT [] +synonym: "up-regulation of chromatin silencing" EXACT [] +synonym: "upregulation of chromatin silencing" EXACT [] +is_a: GO:0031935 ! regulation of chromatin silencing +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006342 ! chromatin silencing +relationship: positively_regulates GO:0006342 ! chromatin silencing + +[Term] +id: GO:0031938 +name: regulation of chromatin silencing at telomere +namespace: biological_process +def: "Any process that affects the rate, extent or location of chromatin silencing at telomeres." [GOC:mah] +synonym: "regulation of heterochromatic silencing at telomere" EXACT [] +is_a: GO:0031935 ! regulation of chromatin silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006348 ! chromatin silencing at telomere +relationship: regulates GO:0006348 ! chromatin silencing at telomere + +[Term] +id: GO:0031939 +name: negative regulation of chromatin silencing at telomere +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah] +synonym: "down regulation of chromatin silencing at telomere" EXACT [] +synonym: "down-regulation of chromatin silencing at telomere" EXACT [] +synonym: "downregulation of chromatin silencing at telomere" EXACT [] +synonym: "inhibition of chromatin silencing at telomere" NARROW [] +synonym: "negative regulation of heterochromatic silencing at telomere" EXACT [] +is_a: GO:0031936 ! negative regulation of chromatin silencing +is_a: GO:0031938 ! regulation of chromatin silencing at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006348 ! chromatin silencing at telomere +relationship: negatively_regulates GO:0006348 ! chromatin silencing at telomere + +[Term] +id: GO:0031940 +name: positive regulation of chromatin silencing at telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah] +synonym: "activation of chromatin silencing at telomere" NARROW [] +synonym: "positive regulation of heterochromatic silencing at telomere" EXACT [] +synonym: "stimulation of chromatin silencing at telomere" NARROW [] +synonym: "up regulation of chromatin silencing at telomere" EXACT [] +synonym: "up-regulation of chromatin silencing at telomere" EXACT [] +synonym: "upregulation of chromatin silencing at telomere" EXACT [] +is_a: GO:0031937 ! positive regulation of chromatin silencing +is_a: GO:0031938 ! regulation of chromatin silencing at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006348 ! chromatin silencing at telomere +relationship: positively_regulates GO:0006348 ! chromatin silencing at telomere + +[Term] +id: GO:0031941 +name: filamentous actin +namespace: cellular_component +def: "A two-stranded helical polymer of the protein actin." [GOC:mah] +comment: Note that this term refers only to the actin portion of a microfilament, and does not encompass associated proteins. See also the cellular component term 'actin filament ; GO:0005884'. +synonym: "F-actin" EXACT [] +xref: Wikipedia:Actin +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005884 ! actin filament + +[Term] +id: GO:0031942 +name: i-AAA complex +namespace: cellular_component +def: "Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases." [PMID:16247555, PMID:16267274] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex + +[Term] +id: GO:0031943 +name: regulation of glucocorticoid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] +synonym: "regulation of glucocorticoid metabolism" EXACT [] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008211 ! glucocorticoid metabolic process +relationship: regulates GO:0008211 ! glucocorticoid metabolic process + +[Term] +id: GO:0031944 +name: negative regulation of glucocorticoid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] +synonym: "down regulation of glucocorticoid metabolic process" EXACT [] +synonym: "down-regulation of glucocorticoid metabolic process" EXACT [] +synonym: "downregulation of glucocorticoid metabolic process" EXACT [] +synonym: "inhibition of glucocorticoid metabolic process" NARROW [] +synonym: "negative regulation of glucocorticoid metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0031943 ! regulation of glucocorticoid metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045939 ! negative regulation of steroid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008211 ! glucocorticoid metabolic process +relationship: negatively_regulates GO:0008211 ! glucocorticoid metabolic process + +[Term] +id: GO:0031945 +name: positive regulation of glucocorticoid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] +synonym: "activation of glucocorticoid metabolic process" NARROW [] +synonym: "positive regulation of glucocorticoid metabolism" EXACT [] +synonym: "stimulation of glucocorticoid metabolic process" NARROW [] +synonym: "up regulation of glucocorticoid metabolic process" EXACT [] +synonym: "up-regulation of glucocorticoid metabolic process" EXACT [] +synonym: "upregulation of glucocorticoid metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0031943 ! regulation of glucocorticoid metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045940 ! positive regulation of steroid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008211 ! glucocorticoid metabolic process +relationship: positively_regulates GO:0008211 ! glucocorticoid metabolic process + +[Term] +id: GO:0031946 +name: regulation of glucocorticoid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] +is_a: GO:0031943 ! regulation of glucocorticoid metabolic process +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006704 ! glucocorticoid biosynthetic process +relationship: regulates GO:0006704 ! glucocorticoid biosynthetic process + +[Term] +id: GO:0031947 +name: negative regulation of glucocorticoid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] +synonym: "down regulation of glucocorticoid biosynthetic process" EXACT [] +synonym: "down-regulation of glucocorticoid biosynthetic process" EXACT [] +synonym: "downregulation of glucocorticoid biosynthetic process" EXACT [] +synonym: "inhibition of glucocorticoid biosynthetic process" NARROW [] +is_a: GO:0031944 ! negative regulation of glucocorticoid metabolic process +is_a: GO:0031946 ! regulation of glucocorticoid biosynthetic process +is_a: GO:0090032 ! negative regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006704 ! glucocorticoid biosynthetic process +relationship: negatively_regulates GO:0006704 ! glucocorticoid biosynthetic process + +[Term] +id: GO:0031948 +name: positive regulation of glucocorticoid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] +synonym: "activation of glucocorticoid biosynthetic process" NARROW [] +synonym: "stimulation of glucocorticoid biosynthetic process" NARROW [] +synonym: "up regulation of glucocorticoid biosynthetic process" EXACT [] +synonym: "up-regulation of glucocorticoid biosynthetic process" EXACT [] +synonym: "upregulation of glucocorticoid biosynthetic process" EXACT [] +is_a: GO:0031945 ! positive regulation of glucocorticoid metabolic process +is_a: GO:0031946 ! regulation of glucocorticoid biosynthetic process +is_a: GO:0090031 ! positive regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006704 ! glucocorticoid biosynthetic process +relationship: positively_regulates GO:0006704 ! glucocorticoid biosynthetic process + +[Term] +id: GO:0031949 +name: regulation of glucocorticoid catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0031943 ! regulation of glucocorticoid metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006713 ! glucocorticoid catabolic process +relationship: regulates GO:0006713 ! glucocorticoid catabolic process + +[Term] +id: GO:0031950 +name: negative regulation of glucocorticoid catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] +synonym: "down regulation of glucocorticoid catabolic process" EXACT [] +synonym: "down-regulation of glucocorticoid catabolic process" EXACT [] +synonym: "downregulation of glucocorticoid catabolic process" EXACT [] +synonym: "inhibition of glucocorticoid catabolic process" NARROW [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0031944 ! negative regulation of glucocorticoid metabolic process +is_a: GO:0031949 ! regulation of glucocorticoid catabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006713 ! glucocorticoid catabolic process +relationship: negatively_regulates GO:0006713 ! glucocorticoid catabolic process + +[Term] +id: GO:0031951 +name: positive regulation of glucocorticoid catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] +synonym: "activation of glucocorticoid catabolic process" NARROW [] +synonym: "stimulation of glucocorticoid catabolic process" NARROW [] +synonym: "up regulation of glucocorticoid catabolic process" EXACT [] +synonym: "up-regulation of glucocorticoid catabolic process" EXACT [] +synonym: "upregulation of glucocorticoid catabolic process" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0031945 ! positive regulation of glucocorticoid metabolic process +is_a: GO:0031949 ! regulation of glucocorticoid catabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006713 ! glucocorticoid catabolic process +relationship: positively_regulates GO:0006713 ! glucocorticoid catabolic process + +[Term] +id: GO:0031952 +name: regulation of protein autophosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] +synonym: "regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] +is_a: GO:0001932 ! regulation of protein phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046777 ! protein autophosphorylation +relationship: has_part GO:0045859 ! regulation of protein kinase activity +relationship: regulates GO:0046777 ! protein autophosphorylation + +[Term] +id: GO:0031953 +name: negative regulation of protein autophosphorylation +namespace: biological_process +def: "Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] +synonym: "down regulation of protein amino acid autophosphorylation" EXACT [] +synonym: "down-regulation of protein amino acid autophosphorylation" EXACT [] +synonym: "downregulation of protein amino acid autophosphorylation" EXACT [] +synonym: "inhibition of protein amino acid autophosphorylation" NARROW [] +synonym: "negative regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0031952 ! regulation of protein autophosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046777 ! protein autophosphorylation +relationship: has_part GO:0006469 ! negative regulation of protein kinase activity +relationship: negatively_regulates GO:0046777 ! protein autophosphorylation + +[Term] +id: GO:0031954 +name: positive regulation of protein autophosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] +synonym: "activation of protein amino acid autophosphorylation" NARROW [] +synonym: "positive regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] +synonym: "stimulation of protein amino acid autophosphorylation" NARROW [] +synonym: "up regulation of protein amino acid autophosphorylation" EXACT [] +synonym: "up-regulation of protein amino acid autophosphorylation" EXACT [] +synonym: "upregulation of protein amino acid autophosphorylation" EXACT [] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0031952 ! regulation of protein autophosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046777 ! protein autophosphorylation +relationship: has_part GO:0045860 ! positive regulation of protein kinase activity +relationship: positively_regulates GO:0046777 ! protein autophosphorylation + +[Term] +id: GO:0031955 +name: short-chain fatty acid-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6." [EC:6.2.1.3, GOC:mah] +synonym: "short-chain fatty acid activation" RELATED [] +synonym: "short-chain fatty-acid-CoA ligase activity" EXACT [GOC:bf] +synonym: "short-chain-fatty-acid-CoA ligase activity" EXACT [] +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0031956 +name: medium-chain fatty acid-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12." [EC:6.2.1.3, GOC:mah] +synonym: "medium-chain fatty acid activation" RELATED [] +synonym: "medium-chain fatty-acid-CoA ligase activity" EXACT [GOC:bf] +synonym: "medium-chain-fatty-acid-CoA ligase activity" EXACT [] +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0031957 +name: very long-chain fatty acid-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [EC:6.2.1.3, GOC:mah] +synonym: "very-long-chain fatty acid activation" RELATED [] +synonym: "very-long-chain fatty acid-CoA ligase activity" EXACT [] +synonym: "very-long-chain-fatty-acid-CoA ligase activity" EXACT [] +xref: Reactome:R-HSA-5695957 "ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA" +xref: Reactome:R-HSA-5696007 "ACSF3 ligates CoA-SH to VLCFA" +xref: Reactome:R-HSA-8875077 "SLC27A3 ligates CoA-SH to VLCFA" +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0031958 +name: corticosteroid receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724] +synonym: "corticosteroid receptor signalling pathway" EXACT [] +is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0031959 +name: mineralocorticoid receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724] +synonym: "mineralocorticoid receptor signalling pathway" EXACT [] +is_a: GO:0031958 ! corticosteroid receptor signaling pathway + +[Term] +id: GO:0031960 +name: response to corticosteroid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." [GOC:mah, PMID:11027914] +synonym: "response to corticosteroid stimulus" EXACT [GOC:dos] +is_a: GO:0048545 ! response to steroid hormone + +[Term] +id: GO:0031961 +name: cortisol receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cortisol receptor." [GOC:mah, PMID:12511169] +is_a: GO:0035259 ! glucocorticoid receptor binding + +[Term] +id: GO:0031962 +name: mineralocorticoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mineralocorticoid receptor." [GOC:mah, PMID:12511169] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0035258 ! steroid hormone receptor binding + +[Term] +id: GO:0031963 +name: cortisol receptor activity +namespace: molecular_function +def: "Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function." [GOC:mah, PMID:12511169] +comment: For cortisol receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038049' or ligand-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038049'. +is_a: GO:0004883 ! glucocorticoid receptor activity + +[Term] +id: GO:0031964 +name: beta-alanyl-histamine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine." [GOC:rc, PMID:16299587] +synonym: "carcinine hydrolase activity" EXACT [] +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0031965 +name: nuclear membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] +xref: NIF_Subcellular:sao1687101204 +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0005635 ! nuclear envelope + +[Term] +id: GO:0031966 +name: mitochondrial membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:mah, NIF_Subcellular:sao1045389829] +xref: NIF_Subcellular:sao1045389829 +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0005740 ! mitochondrial envelope + +[Term] +id: GO:0031967 +name: organelle envelope +namespace: cellular_component +def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] +subset: goslim_mouse +is_a: GO:0031975 ! envelope +relationship: part_of GO:0043227 ! membrane-bounded organelle +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0031968 +name: organelle outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah] +is_a: GO:0019867 ! outer membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0031967 ! organelle envelope + +[Term] +id: GO:0031969 +name: chloroplast membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope." [GOC:mah, GOC:pz] +xref: Wikipedia:Chloroplast_membrane +is_a: GO:0042170 ! plastid membrane +relationship: part_of GO:0009941 ! chloroplast envelope + +[Term] +id: GO:0031970 +name: organelle envelope lumen +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of an organelle envelope." [GOC:mah] +synonym: "organelle intermembrane space" EXACT [] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0031967 ! organelle envelope + +[Term] +id: GO:0031972 +name: chloroplast intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of a chloroplast envelope." [GOC:mah] +synonym: "chloroplast envelope lumen" EXACT [] +is_a: GO:0009529 ! plastid intermembrane space +relationship: part_of GO:0009941 ! chloroplast envelope + +[Term] +id: GO:0031973 +name: chromoplast intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of a chromoplast envelope." [GOC:mah] +synonym: "chromoplast envelope lumen" EXACT [] +is_a: GO:0009529 ! plastid intermembrane space +relationship: part_of GO:0031898 ! chromoplast envelope + +[Term] +id: GO:0031974 +name: membrane-enclosed lumen +namespace: cellular_component +def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0031975 +name: envelope +namespace: cellular_component +def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0031976 +name: plastid thylakoid +namespace: cellular_component +def: "Any thylakoid within a plastid." [GOC:pz] +is_a: GO:0009579 ! thylakoid +is_a: GO:0031984 ! organelle subcompartment +intersection_of: GO:0009579 ! thylakoid +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0031977 +name: thylakoid lumen +namespace: cellular_component +def: "The volume enclosed by a thylakoid membrane." [GOC:mah, GOC:pz] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009579 ! thylakoid + +[Term] +id: GO:0031978 +name: plastid thylakoid lumen +namespace: cellular_component +def: "The volume enclosed by a plastid thylakoid membrane." [GOC:mah] +is_a: GO:0031977 ! thylakoid lumen +relationship: part_of GO:0031976 ! plastid thylakoid + +[Term] +id: GO:0031979 +name: plasma membrane-derived thylakoid lumen +namespace: cellular_component +def: "The volume enclosed by a plasma membrane-derived thylakoid." [GOC:mah, GOC:mtg_sensu] +synonym: "plasma membrane thylakoid lumen" EXACT [] +is_a: GO:0031977 ! thylakoid lumen +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0030075 ! bacterial thylakoid + +[Term] +id: GO:0031981 +name: nuclear lumen +namespace: cellular_component +def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0031982 +name: vesicle +namespace: cellular_component +alt_id: GO:0031988 +def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles] +subset: goslim_pir +synonym: "membrane-bounded vesicle" RELATED [] +synonym: "membrane-enclosed vesicle" RELATED [] +xref: NIF_Subcellular:sao221389602 +xref: Wikipedia:Vesicle_(biology) +is_a: GO:0043227 ! membrane-bounded organelle + +[Term] +id: GO:0031983 +name: vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane or protein that forms a vesicle." [GOC:mah, GOC:vesicles] +xref: NIF_Subcellular:sao797538226 +is_a: GO:0043233 ! organelle lumen +relationship: part_of GO:0031982 ! vesicle + +[Term] +id: GO:0031984 +name: organelle subcompartment +namespace: cellular_component +def: "A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle." [GOC:mah, GOC:pz] +comment: Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles. +synonym: "suborganelle compartment" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043227 ! membrane-bounded organelle +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0031985 +name: Golgi cisterna +namespace: cellular_component +def: "Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex." [GOC:mah] +synonym: "Golgi lamellae" RELATED [NIF_Subcellular:sao561419532] +xref: NIF_Subcellular:sao561419532 +is_a: GO:0098791 ! Golgi apparatus subcompartment +relationship: part_of GO:0005795 ! Golgi stack + +[Term] +id: GO:0031986 +name: proteinoplast +namespace: cellular_component +def: "A leucoplast in which protein is stored." [GOC:pz] +xref: Wikipedia:Proteinoplast +is_a: GO:0009516 ! leucoplast + +[Term] +id: GO:0031987 +name: locomotion involved in locomotory behavior +namespace: biological_process +def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah] +synonym: "locomotion during locomotory behaviour" EXACT [] +is_a: GO:0040011 ! locomotion +intersection_of: GO:0040011 ! locomotion +intersection_of: part_of GO:0007626 ! locomotory behavior +relationship: part_of GO:0007626 ! locomotory behavior + +[Term] +id: GO:0031989 +name: bombesin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "bombesin receptor signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0031990 +name: mRNA export from nucleus in response to heat stress +namespace: biological_process +def: "The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export." [GOC:mah, GOC:vw] +synonym: "mRNA export from cell nucleus during heat stress" EXACT [] +synonym: "mRNA export from nucleus during heat stress" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006406 ! mRNA export from nucleus +is_a: GO:0034605 ! cellular response to heat + +[Term] +id: GO:0031991 +name: regulation of actomyosin contractile ring contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of contractile ring contraction involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "regulation of contractile ring contraction involved in cytokinesis during cell cycle" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0032954 ! regulation of cytokinetic process +is_a: GO:0110020 ! regulation of actomyosin structure organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000916 ! actomyosin contractile ring contraction +relationship: regulates GO:0000916 ! actomyosin contractile ring contraction + +[Term] +id: GO:0031992 +name: energy transducer activity +namespace: molecular_function +def: "The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell." [GOC:go_curators] +subset: goslim_pir +synonym: "light harvesting activity" RELATED [] +synonym: "photon capture" RELATED [] +is_a: GO:0060089 ! molecular transducer activity + +[Term] +id: GO:0031993 +name: light transducer activity +namespace: molecular_function +def: "Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell." [GOC:mah, GOC:mlg] +is_a: GO:0031992 ! energy transducer activity +relationship: part_of GO:0009583 ! detection of light stimulus + +[Term] +id: GO:0031994 +name: insulin-like growth factor I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with insulin-like growth factor I." [GOC:mah] +subset: goslim_chembl +synonym: "IGF-I binding" EXACT [] +is_a: GO:0005520 ! insulin-like growth factor binding + +[Term] +id: GO:0031995 +name: insulin-like growth factor II binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with insulin-like growth factor II." [GOC:mah] +subset: goslim_chembl +synonym: "IGF-II binding" EXACT [] +is_a: GO:0005520 ! insulin-like growth factor binding + +[Term] +id: GO:0031996 +name: thioesterase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any thioesterase enzyme." [GOC:dl] +synonym: "thiolesterase binding" EXACT [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0031997 +name: N-terminal myristoylation domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin." [GOC:dl, GOC:jsg, PMID:15632291] +is_a: GO:0047485 ! protein N-terminus binding + +[Term] +id: GO:0031998 +name: regulation of fatty acid beta-oxidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation." [GOC:mah] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0046320 ! regulation of fatty acid oxidation +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006635 ! fatty acid beta-oxidation +relationship: regulates GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0031999 +name: negative regulation of fatty acid beta-oxidation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah] +synonym: "down regulation of fatty acid beta-oxidation" EXACT [] +synonym: "down-regulation of fatty acid beta-oxidation" EXACT [] +synonym: "downregulation of fatty acid beta-oxidation" EXACT [] +synonym: "inhibition of fatty acid beta-oxidation" NARROW [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0031998 ! regulation of fatty acid beta-oxidation +is_a: GO:0046322 ! negative regulation of fatty acid oxidation +is_a: GO:0050995 ! negative regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006635 ! fatty acid beta-oxidation +relationship: negatively_regulates GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0032000 +name: positive regulation of fatty acid beta-oxidation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah] +synonym: "activation of fatty acid beta-oxidation" NARROW [] +synonym: "stimulation of fatty acid beta-oxidation" NARROW [] +synonym: "up regulation of fatty acid beta-oxidation" EXACT [] +synonym: "up-regulation of fatty acid beta-oxidation" EXACT [] +synonym: "upregulation of fatty acid beta-oxidation" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0031998 ! regulation of fatty acid beta-oxidation +is_a: GO:0046321 ! positive regulation of fatty acid oxidation +is_a: GO:0050996 ! positive regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006635 ! fatty acid beta-oxidation +relationship: positively_regulates GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0032001 +name: 1,4-alpha-glucan 6-alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan." [EC:2.4.1.24] +synonym: "1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [] +synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity" EXACT [] +synonym: "D-glucosyltransferase" BROAD [] +synonym: "oligoglucan-branching glycosyltransferase activity" RELATED [EC:2.4.1.24] +synonym: "T-enzyme" NARROW [] +xref: EC:2.4.1.24 +xref: MetaCyc:2.4.1.24-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0032002 +name: interleukin-28 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1)." [GOC:rph] +synonym: "IL-28 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0032003 +name: interleukin-28 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-28 receptor." [GOC:rph] +synonym: "IL-28" NARROW [] +synonym: "interleukin-28 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0032005 +name: signal transduction involved in positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:mah] +is_a: GO:0007165 ! signal transduction +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +intersection_of: GO:0007165 ! signal transduction +intersection_of: positively_regulates GO:0000747 ! conjugation with cellular fusion + +[Term] +id: GO:0032006 +name: regulation of TOR signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of TOR signaling." [GOC:mah] +synonym: "regulation of target of rapamycin signaling pathway" EXACT [] +synonym: "regulation of target of rapamycin signalling pathway" EXACT [] +synonym: "regulation of TOR signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of TOR signaling pathway" EXACT [] +synonym: "regulation of TOR signalling pathway" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031929 ! TOR signaling +relationship: regulates GO:0031929 ! TOR signaling + +[Term] +id: GO:0032007 +name: negative regulation of TOR signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling." [GOC:mah] +synonym: "down regulation of TOR signaling pathway" EXACT [] +synonym: "down-regulation of TOR signaling pathway" EXACT [] +synonym: "downregulation of TOR signaling pathway" EXACT [] +synonym: "inhibition of TOR signaling pathway" NARROW [] +synonym: "negative regulation of target of rapamycin signaling pathway" EXACT [] +synonym: "negative regulation of target of rapamycin signalling pathway" EXACT [] +synonym: "negative regulation of TOR signaling cascade" RELATED [GOC:signaling] +synonym: "negative regulation of TOR signaling pathway" EXACT [] +synonym: "negative regulation of TOR signalling pathway" EXACT [] +is_a: GO:0032006 ! regulation of TOR signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031929 ! TOR signaling +relationship: negatively_regulates GO:0031929 ! TOR signaling + +[Term] +id: GO:0032008 +name: positive regulation of TOR signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of TOR signaling." [GOC:mah] +synonym: "activation of TOR signaling pathway" NARROW [] +synonym: "positive regulation of target of rapamycin signaling pathway" EXACT [] +synonym: "positive regulation of target of rapamycin signalling pathway" EXACT [] +synonym: "positive regulation of TOR signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of TOR signaling pathway" EXACT [] +synonym: "positive regulation of TOR signalling pathway" EXACT [] +synonym: "stimulation of TOR signaling pathway" NARROW [] +synonym: "up regulation of TOR signaling pathway" EXACT [] +synonym: "up-regulation of TOR signaling pathway" EXACT [] +synonym: "upregulation of TOR signaling pathway" EXACT [] +is_a: GO:0032006 ! regulation of TOR signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031929 ! TOR signaling +relationship: positively_regulates GO:0031929 ! TOR signaling + +[Term] +id: GO:0032009 +name: early phagosome +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis." [GOC:mah, PMID:12388753] +synonym: "early phagocytic vesicle" EXACT [] +is_a: GO:0045335 ! phagocytic vesicle + +[Term] +id: GO:0032010 +name: phagolysosome +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes." [GOC:mah, PMID:12388753] +synonym: "late phagocytic vesicle" RELATED [] +synonym: "late phagosome" RELATED [] +xref: Wikipedia:Phagolysosome +is_a: GO:0005767 ! secondary lysosome +is_a: GO:0045335 ! phagocytic vesicle + +[Term] +id: GO:0032011 +name: ARF protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state." [GOC:mah] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0032012 +name: regulation of ARF protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032011 ! ARF protein signal transduction +relationship: regulates GO:0032011 ! ARF protein signal transduction + +[Term] +id: GO:0032013 +name: negative regulation of ARF protein signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] +synonym: "down regulation of ARF protein signal transduction" EXACT [] +synonym: "down-regulation of ARF protein signal transduction" EXACT [] +synonym: "downregulation of ARF protein signal transduction" EXACT [] +synonym: "inhibition of ARF protein signal transduction" NARROW [] +is_a: GO:0032012 ! regulation of ARF protein signal transduction +is_a: GO:0046580 ! negative regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032011 ! ARF protein signal transduction +relationship: negatively_regulates GO:0032011 ! ARF protein signal transduction + +[Term] +id: GO:0032014 +name: positive regulation of ARF protein signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] +synonym: "activation of ARF protein signal transduction" NARROW [] +synonym: "stimulation of ARF protein signal transduction" NARROW [] +synonym: "up regulation of ARF protein signal transduction" EXACT [] +synonym: "up-regulation of ARF protein signal transduction" EXACT [] +synonym: "upregulation of ARF protein signal transduction" EXACT [] +is_a: GO:0032012 ! regulation of ARF protein signal transduction +is_a: GO:0046579 ! positive regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032011 ! ARF protein signal transduction +relationship: positively_regulates GO:0032011 ! ARF protein signal transduction + +[Term] +id: GO:0032015 +name: regulation of Ran protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031291 ! Ran protein signal transduction +relationship: regulates GO:0031291 ! Ran protein signal transduction + +[Term] +id: GO:0032016 +name: negative regulation of Ran protein signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] +synonym: "down regulation of Ran protein signal transduction" EXACT [] +synonym: "down-regulation of Ran protein signal transduction" EXACT [] +synonym: "downregulation of Ran protein signal transduction" EXACT [] +synonym: "inhibition of Ran protein signal transduction" NARROW [] +is_a: GO:0032015 ! regulation of Ran protein signal transduction +is_a: GO:0046580 ! negative regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031291 ! Ran protein signal transduction +relationship: negatively_regulates GO:0031291 ! Ran protein signal transduction + +[Term] +id: GO:0032017 +name: positive regulation of Ran protein signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] +synonym: "activation of Ran protein signal transduction" NARROW [] +synonym: "stimulation of Ran protein signal transduction" NARROW [] +synonym: "up regulation of Ran protein signal transduction" EXACT [] +synonym: "up-regulation of Ran protein signal transduction" EXACT [] +synonym: "upregulation of Ran protein signal transduction" EXACT [] +is_a: GO:0032015 ! regulation of Ran protein signal transduction +is_a: GO:0046579 ! positive regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031291 ! Ran protein signal transduction +relationship: positively_regulates GO:0031291 ! Ran protein signal transduction + +[Term] +id: GO:0032018 +name: 2-methylbutanol:NADP oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+." [GOC:mah, PMID:12210903] +synonym: "2-methylbutanal reductase (NADP) activity" EXACT [] +synonym: "2-methylbutyraldehyde reductase (NADP) activity" EXACT [] +is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity + +[Term] +id: GO:0032019 +name: mitochondrial cloud +namespace: cellular_component +def: "A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material." [PMID:6541166] +synonym: "Balbiani body" EXACT [] +synonym: "mitochondrial aggregate" RELATED [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032020 +name: ISG15-protein conjugation +namespace: biological_process +def: "The covalent addition to a protein of ISG15, a ubiquitin-like protein." [GOC:mah] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0032021 +name: NELF complex +namespace: cellular_component +def: "A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing." [PMID:12612062] +synonym: "negative elongation factor complex" EXACT [] +is_a: GO:0008023 ! transcription elongation factor complex + +[Term] +id: GO:0032023 +name: trypsinogen activation +namespace: biological_process +def: "The proteolytic processing of trypsinogen to the active form, trypsin." [GOC:mah] +synonym: "cleavage of trypsinogen to trypsin" EXACT [] +is_a: GO:0031638 ! zymogen activation + +[Term] +id: GO:0032024 +name: positive regulation of insulin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] +synonym: "activation of insulin secretion" NARROW [] +synonym: "stimulation of insulin secretion" NARROW [] +synonym: "up regulation of insulin secretion" EXACT [] +synonym: "up-regulation of insulin secretion" EXACT [] +synonym: "upregulation of insulin secretion" EXACT [] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0050796 ! regulation of insulin secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030073 ! insulin secretion +relationship: positively_regulates GO:0030073 ! insulin secretion + +[Term] +id: GO:0032025 +name: response to cobalt ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus." [GOC:mah] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0032026 +name: response to magnesium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus." [GOC:mah] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0032027 +name: myosin light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light chain of a myosin complex." [GOC:mah] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0032028 +name: myosin head/neck binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain." [GOC:mah] +is_a: GO:0032036 ! myosin heavy chain binding + +[Term] +id: GO:0032029 +name: myosin tail binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the tail region of a myosin heavy chain." [GOC:mah] +is_a: GO:0032036 ! myosin heavy chain binding + +[Term] +id: GO:0032030 +name: myosin I light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light chain of a myosin I complex." [GOC:mah] +is_a: GO:0017024 ! myosin I binding +is_a: GO:0032027 ! myosin light chain binding + +[Term] +id: GO:0032031 +name: myosin I head/neck binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the head/neck region of a myosin I heavy chain." [GOC:mah] +is_a: GO:0032028 ! myosin head/neck binding +is_a: GO:0032037 ! myosin I heavy chain binding + +[Term] +id: GO:0032032 +name: myosin I tail binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the tail region of a myosin I heavy chain." [GOC:mah] +is_a: GO:0032029 ! myosin tail binding +is_a: GO:0032037 ! myosin I heavy chain binding + +[Term] +id: GO:0032033 +name: myosin II light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light chain of a myosin II complex." [GOC:mah] +is_a: GO:0032027 ! myosin light chain binding +is_a: GO:0045159 ! myosin II binding + +[Term] +id: GO:0032034 +name: myosin II head/neck binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the head/neck region of a myosin II heavy chain." [GOC:mah] +is_a: GO:0032028 ! myosin head/neck binding +is_a: GO:0032038 ! myosin II heavy chain binding + +[Term] +id: GO:0032035 +name: myosin II tail binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the tail region of a myosin II heavy chain." [GOC:mah] +is_a: GO:0032029 ! myosin tail binding +is_a: GO:0032038 ! myosin II heavy chain binding + +[Term] +id: GO:0032036 +name: myosin heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heavy chain of a myosin complex." [GOC:mah] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0032037 +name: myosin I heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heavy chain of a myosin I complex." [GOC:mah] +is_a: GO:0017024 ! myosin I binding +is_a: GO:0032036 ! myosin heavy chain binding + +[Term] +id: GO:0032038 +name: myosin II heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heavy chain of a myosin II complex." [GOC:mah] +is_a: GO:0032036 ! myosin heavy chain binding +is_a: GO:0045159 ! myosin II binding + +[Term] +id: GO:0032039 +name: integrator complex +namespace: cellular_component +def: "A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II." [PMID:16239144] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15979 xsd:anyURI + +[Term] +id: GO:0032040 +name: small-subunit processome +namespace: cellular_component +def: "A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins." [GOC:krc, GOC:vw, PMID:12068309, PMID:12957375, PMID:15120992, PMID:15590835] +synonym: "small subunit processome" EXACT [] +synonym: "SSU processome" EXACT [] +is_a: GO:0030684 ! preribosome +relationship: has_part GO:0034455 ! t-UTP complex + +[Term] +id: GO:0032041 +name: NAD-dependent histone deacetylase activity (H3-K14 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein." [EC:3.5.1.17, RHEA:24548] +xref: EC:3.5.1.98 +is_a: GO:0017136 ! NAD-dependent histone deacetylase activity +is_a: GO:0031078 ! histone deacetylase activity (H3-K14 specific) + +[Term] +id: GO:0032042 +name: mitochondrial DNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mitochondrial DNA." [GOC:mah] +synonym: "mitochondrial DNA metabolism" EXACT [] +synonym: "mtDNA metabolic process" EXACT [] +synonym: "mtDNA metabolism" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +intersection_of: GO:0006259 ! DNA metabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0000002 ! mitochondrial genome maintenance + +[Term] +id: GO:0032043 +name: mitochondrial DNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA." [GOC:mah] +synonym: "mitochondrial DNA breakdown" EXACT [] +synonym: "mitochondrial DNA catabolism" EXACT [] +synonym: "mitochondrial DNA degradation" EXACT [] +synonym: "mtDNA breakdown" EXACT [] +synonym: "mtDNA catabolic process" EXACT [] +synonym: "mtDNA catabolism" EXACT [] +synonym: "mtDNA degradation" EXACT [] +is_a: GO:0006308 ! DNA catabolic process +is_a: GO:0032042 ! mitochondrial DNA metabolic process +intersection_of: GO:0006308 ! DNA catabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0032044 +name: DSIF complex +namespace: cellular_component +def: "A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes." [PMID:12242279, PMID:12653964, PMID:12676794, PMID:16581788, PMID:19460865] +synonym: "5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex" EXACT [] +synonym: "DRB sensitivity inducing factor complex" EXACT [] +synonym: "Spt4-Spt5 complex" EXACT [] +synonym: "Spt5-Spt4 complex" EXACT [GOC:vw] +is_a: GO:0008023 ! transcription elongation factor complex + +[Term] +id: GO:0032045 +name: guanyl-nucleotide exchange factor complex +namespace: cellular_component +def: "A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase." [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032046 +name: micropexophagy-specific membrane apparatus +namespace: cellular_component +def: "A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole." [PMID:15563611] +synonym: "micropexophagic apparatus" EXACT [] +synonym: "MIPA" EXACT [] +is_a: GO:0031984 ! organelle subcompartment +relationship: part_of GO:0005773 ! vacuole + +[Term] +id: GO:0032047 +name: mitosome +namespace: cellular_component +def: "A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria." [GOC:giardia, PMID:10361303, PMID:14614504, PMID:24316280] +comment: In Giardia species, mitosomes are sometimes present between the two nuclei. +synonym: "crypton" EXACT [] +xref: Wikipedia:Mitosome +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032048 +name: cardiolipin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol." [GOC:mah] +synonym: "cardiolipin metabolism" EXACT [] +synonym: "diphosphatidylglycerol metabolic process" RELATED [] +synonym: "diphosphatidylglycerol metabolism" RELATED [] +is_a: GO:0046471 ! phosphatidylglycerol metabolic process + +[Term] +id: GO:0032049 +name: cardiolipin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol." [GOC:mah] +synonym: "diphosphatidylglycerol biosynthesis" RELATED [] +synonym: "diphosphatidylglycerol biosynthetic process" RELATED [] +xref: MetaCyc:PWY-5269 +is_a: GO:0006655 ! phosphatidylglycerol biosynthetic process +is_a: GO:0032048 ! cardiolipin metabolic process + +[Term] +id: GO:0032050 +name: clathrin heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a clathrin heavy chain." [GOC:mah] +is_a: GO:0030276 ! clathrin binding + +[Term] +id: GO:0032051 +name: clathrin light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a clathrin light chain." [GOC:mah] +is_a: GO:0030276 ! clathrin binding + +[Term] +id: GO:0032052 +name: bile acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:rph] +is_a: GO:0033293 ! monocarboxylic acid binding + +[Term] +id: GO:0032053 +name: ciliary basal body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum)." [GOC:cilia, GOC:dph, GOC:jl, GOC:krc, GOC:mah, PMID:9889124] +synonym: "microtubule basal body organisation" BROAD [GOC:mah] +synonym: "microtubule basal body organization" BROAD [] +synonym: "microtubule basal body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0031023 ! microtubule organizing center organization +is_a: GO:0044782 ! cilium organization + +[Term] +id: GO:0032055 +name: negative regulation of translation in response to stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] +synonym: "down regulation of translation in response to stress" EXACT [] +synonym: "down-regulation of translation in response to stress" EXACT [] +synonym: "downregulation of translation in response to stress" EXACT [] +synonym: "inhibition of translation in response to stress" NARROW [] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0043555 ! regulation of translation in response to stress + +[Term] +id: GO:0032056 +name: positive regulation of translation in response to stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] +synonym: "activation of translation in response to stress" NARROW [] +synonym: "stimulation of translation in response to stress" NARROW [] +synonym: "up regulation of translation in response to stress" EXACT [] +synonym: "up-regulation of translation in response to stress" EXACT [] +synonym: "upregulation of translation in response to stress" EXACT [] +is_a: GO:0043555 ! regulation of translation in response to stress +is_a: GO:0045727 ! positive regulation of translation + +[Term] +id: GO:0032057 +name: negative regulation of translational initiation in response to stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] +synonym: "down regulation of translation initiation in response to stress" EXACT [] +synonym: "down-regulation of translation initiation in response to stress" EXACT [] +synonym: "downregulation of translation initiation in response to stress" EXACT [] +synonym: "inhibition of translation initiation in response to stress" NARROW [] +is_a: GO:0032055 ! negative regulation of translation in response to stress +is_a: GO:0043558 ! regulation of translational initiation in response to stress +is_a: GO:0045947 ! negative regulation of translational initiation + +[Term] +id: GO:0032058 +name: positive regulation of translational initiation in response to stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] +synonym: "activation of translation initiation in response to stress" NARROW [] +synonym: "stimulation of translation initiation in response to stress" NARROW [] +synonym: "up regulation of translation initiation in response to stress" EXACT [] +synonym: "up-regulation of translation initiation in response to stress" EXACT [] +synonym: "upregulation of translation initiation in response to stress" EXACT [] +is_a: GO:0032056 ! positive regulation of translation in response to stress +is_a: GO:0043558 ! regulation of translational initiation in response to stress +is_a: GO:0045948 ! positive regulation of translational initiation + +[Term] +id: GO:0032059 +name: bleb +namespace: cellular_component +def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] +subset: goslim_pir +synonym: "plasma membrane bleb" EXACT [GOC:pr] +xref: Wikipedia:Bleb_(cell_biology) +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0032060 +name: bleb assembly +namespace: biological_process +def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] +synonym: "blebbing" BROAD [GOC:pr] +synonym: "cell blebbing" EXACT [] +synonym: "membrane blebbing" BROAD [GOC:pr] +synonym: "plasma membrane bleb assembly" EXACT [GOC:pr] +synonym: "plasma membrane blebbing" EXACT [GOC:pr] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0032061 +name: negative regulation of translation in response to osmotic stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] +synonym: "down regulation of translation in response to osmotic stress" EXACT [] +synonym: "down-regulation of translation in response to osmotic stress" EXACT [] +synonym: "downregulation of translation in response to osmotic stress" EXACT [] +synonym: "inhibition of translation in response to osmotic stress" NARROW [] +is_a: GO:0032055 ! negative regulation of translation in response to stress +is_a: GO:0043557 ! regulation of translation in response to osmotic stress + +[Term] +id: GO:0032062 +name: positive regulation of translation in response to osmotic stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] +synonym: "activation of translation in response to osmotic stress" NARROW [] +synonym: "stimulation of translation in response to osmotic stress" NARROW [] +synonym: "up regulation of translation in response to osmotic stress" EXACT [] +synonym: "up-regulation of translation in response to osmotic stress" EXACT [] +synonym: "upregulation of translation in response to osmotic stress" EXACT [] +is_a: GO:0032056 ! positive regulation of translation in response to stress +is_a: GO:0043557 ! regulation of translation in response to osmotic stress + +[Term] +id: GO:0032063 +name: negative regulation of translational initiation in response to osmotic stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] +synonym: "down regulation of translation initiation in response to osmotic stress" EXACT [] +synonym: "down-regulation of translation initiation in response to osmotic stress" EXACT [] +synonym: "downregulation of translation initiation in response to osmotic stress" EXACT [] +synonym: "inhibition of translation initiation in response to osmotic stress" NARROW [] +is_a: GO:0032057 ! negative regulation of translational initiation in response to stress +is_a: GO:0032061 ! negative regulation of translation in response to osmotic stress +is_a: GO:0043561 ! regulation of translational initiation in response to osmotic stress + +[Term] +id: GO:0032064 +name: positive regulation of translational initiation in response to osmotic stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] +synonym: "activation of translation initiation in response to osmotic stress" NARROW [] +synonym: "stimulation of translation initiation in response to osmotic stress" NARROW [] +synonym: "up regulation of translation initiation in response to osmotic stress" EXACT [] +synonym: "up-regulation of translation initiation in response to osmotic stress" EXACT [] +synonym: "upregulation of translation initiation in response to osmotic stress" EXACT [] +is_a: GO:0032058 ! positive regulation of translational initiation in response to stress +is_a: GO:0032062 ! positive regulation of translation in response to osmotic stress +is_a: GO:0043561 ! regulation of translational initiation in response to osmotic stress + +[Term] +id: GO:0032065 +name: maintenance of protein location in cell cortex +namespace: biological_process +def: "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." [GOC:vw] +synonym: "cortical protein anchoring" RELATED [] +synonym: "maintenance of protein location in cell cortex" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032507 ! maintenance of protein location in cell +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005938 ! cell cortex +relationship: occurs_in GO:0005938 ! cell cortex + +[Term] +id: GO:0032067 +name: type IV site-specific deoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated)." [PMID:12654995] +synonym: "type IV restriction enzyme activity" EXACT [] +is_a: GO:0015666 ! restriction endodeoxyribonuclease activity + +[Term] +id: GO:0032068 +name: type IV site-specific deoxyribonuclease complex +namespace: cellular_component +def: "A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation." [PMID:12654995] +synonym: "type IV restriction enzyme complex" EXACT [] +is_a: GO:1905347 ! endodeoxyribonuclease complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032069 +name: regulation of nuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] +synonym: "nuclease regulator activity" RELATED [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0051336 ! regulation of hydrolase activity +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004518 ! nuclease activity +relationship: regulates GO:0004518 ! nuclease activity + +[Term] +id: GO:0032070 +name: regulation of deoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] +synonym: "deoxyribonuclease regulator" RELATED [] +synonym: "DNase regulator" RELATED [] +is_a: GO:0032069 ! regulation of nuclease activity +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004536 ! deoxyribonuclease activity +relationship: regulates GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0032071 +name: regulation of endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] +synonym: "endodeoxyribonuclease regulator" RELATED [] +is_a: GO:0032070 ! regulation of deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004520 ! endodeoxyribonuclease activity +relationship: regulates GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0032072 +name: regulation of restriction endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mah] +is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015666 ! restriction endodeoxyribonuclease activity +relationship: regulates GO:0015666 ! restriction endodeoxyribonuclease activity + +[Term] +id: GO:0032073 +name: negative regulation of restriction endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mah] +synonym: "down regulation of restriction endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of restriction endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of restriction endodeoxyribonuclease activity" EXACT [] +synonym: "inhibition of restriction endodeoxyribonuclease activity" NARROW [] +synonym: "restriction alleviation" NARROW [] +synonym: "restriction endodeoxyribonuclease inhibitor" RELATED [] +synonym: "restriction enzyme inhibitor" RELATED [] +is_a: GO:0032072 ! regulation of restriction endodeoxyribonuclease activity +is_a: GO:0032078 ! negative regulation of endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015666 ! restriction endodeoxyribonuclease activity +relationship: negatively_regulates GO:0015666 ! restriction endodeoxyribonuclease activity + +[Term] +id: GO:0032074 +name: negative regulation of nuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] +synonym: "down regulation of nuclease activity" EXACT [] +synonym: "down-regulation of nuclease activity" EXACT [] +synonym: "downregulation of nuclease activity" EXACT [] +synonym: "inhibition of nuclease activity" NARROW [] +synonym: "nuclease inhibitor" RELATED [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0032069 ! regulation of nuclease activity +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004518 ! nuclease activity +relationship: negatively_regulates GO:0004518 ! nuclease activity + +[Term] +id: GO:0032075 +name: positive regulation of nuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] +synonym: "activation of nuclease activity" NARROW [] +synonym: "nuclease activator" RELATED [] +synonym: "stimulation of nuclease activity" NARROW [] +synonym: "up regulation of nuclease activity" EXACT [] +synonym: "up-regulation of nuclease activity" EXACT [] +synonym: "upregulation of nuclease activity" EXACT [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0032069 ! regulation of nuclease activity +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004518 ! nuclease activity +relationship: positively_regulates GO:0004518 ! nuclease activity + +[Term] +id: GO:0032076 +name: negative regulation of deoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] +synonym: "deoxyribonuclease inhibitor" RELATED [] +synonym: "DNase inhibitor" RELATED [] +synonym: "down regulation of deoxyribonuclease activity" EXACT [] +synonym: "down-regulation of deoxyribonuclease activity" EXACT [] +synonym: "downregulation of deoxyribonuclease activity" EXACT [] +synonym: "inhibition of deoxyribonuclease activity" NARROW [] +is_a: GO:0032070 ! regulation of deoxyribonuclease activity +is_a: GO:0032074 ! negative regulation of nuclease activity +is_a: GO:0051053 ! negative regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004536 ! deoxyribonuclease activity +relationship: negatively_regulates GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0032077 +name: positive regulation of deoxyribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] +synonym: "activation of deoxyribonuclease activity" NARROW [] +synonym: "deoxyribonuclease activator" RELATED [] +synonym: "DNase activator" RELATED [] +synonym: "stimulation of deoxyribonuclease activity" NARROW [] +synonym: "up regulation of deoxyribonuclease activity" EXACT [] +synonym: "up-regulation of deoxyribonuclease activity" EXACT [] +synonym: "upregulation of deoxyribonuclease activity" EXACT [] +is_a: GO:0032070 ! regulation of deoxyribonuclease activity +is_a: GO:0032075 ! positive regulation of nuclease activity +is_a: GO:0051054 ! positive regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004536 ! deoxyribonuclease activity +relationship: positively_regulates GO:0004536 ! deoxyribonuclease activity + +[Term] +id: GO:0032078 +name: negative regulation of endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] +synonym: "down regulation of endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of endodeoxyribonuclease activity" EXACT [] +synonym: "endodeoxyribonuclease inhibitor" RELATED [] +synonym: "inhibition of endodeoxyribonuclease activity" NARROW [] +is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity +is_a: GO:0032076 ! negative regulation of deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004520 ! endodeoxyribonuclease activity +relationship: negatively_regulates GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0032079 +name: positive regulation of endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] +synonym: "activation of endodeoxyribonuclease activity" NARROW [] +synonym: "endodeoxyribonuclease activator" RELATED [] +synonym: "stimulation of endodeoxyribonuclease activity" NARROW [] +synonym: "up regulation of endodeoxyribonuclease activity" EXACT [] +synonym: "up-regulation of endodeoxyribonuclease activity" EXACT [] +synonym: "upregulation of endodeoxyribonuclease activity" EXACT [] +is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity +is_a: GO:0032077 ! positive regulation of deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004520 ! endodeoxyribonuclease activity +relationship: positively_regulates GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0032080 +name: negative regulation of type I site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of type I restriction endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of type I restriction endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of type I restriction endodeoxyribonuclease activity" EXACT [] +synonym: "inhibition of type I restriction endodeoxyribonuclease activity" NARROW [] +synonym: "negative regulation of type I restriction endodeoxyribonuclease activity" EXACT [GOC:dph, GOC:tb] +synonym: "type I restriction endodeoxyribonuclease inhibitor" RELATED [] +synonym: "type I restriction enzyme inhibitor" RELATED [] +is_a: GO:0032073 ! negative regulation of restriction endodeoxyribonuclease activity +is_a: GO:0032084 ! regulation of type I site-specific deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009035 ! type I site-specific deoxyribonuclease activity +relationship: negatively_regulates GO:0009035 ! type I site-specific deoxyribonuclease activity + +[Term] +id: GO:0032081 +name: negative regulation of type II site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of type II restriction endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of type II restriction endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of type II restriction endodeoxyribonuclease activity" EXACT [] +synonym: "inhibition of type II restriction endodeoxyribonuclease activity" NARROW [] +synonym: "negative regulation of type II restriction endodeoxyribonuclease activity" EXACT [GOC:dph, GOC:tb] +synonym: "type II restriction endodeoxyribonuclease inhibitor" RELATED [] +synonym: "type II restriction enzyme inhibitor" RELATED [] +is_a: GO:0032073 ! negative regulation of restriction endodeoxyribonuclease activity +is_a: GO:0032085 ! regulation of type II site-specific deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009036 ! type II site-specific deoxyribonuclease activity +relationship: negatively_regulates GO:0009036 ! type II site-specific deoxyribonuclease activity + +[Term] +id: GO:0032082 +name: negative regulation of type III site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of type III restriction endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of type III restriction endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of type III restriction endodeoxyribonuclease activity" EXACT [] +synonym: "inhibition of type III restriction endodeoxyribonuclease activity" NARROW [] +synonym: "negative regulation of type III restriction endodeoxyribonuclease activity" EXACT [GOC:dph, GOC:tb] +synonym: "type III restriction endodeoxyribonuclease inhibitor" RELATED [] +synonym: "type III restriction enzyme inhibitor" RELATED [] +is_a: GO:0032073 ! negative regulation of restriction endodeoxyribonuclease activity +is_a: GO:0032086 ! regulation of type III site-specific deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015668 ! type III site-specific deoxyribonuclease activity +relationship: negatively_regulates GO:0015668 ! type III site-specific deoxyribonuclease activity + +[Term] +id: GO:0032083 +name: negative regulation of type IV site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of type IV restriction endodeoxyribonuclease activity" EXACT [] +synonym: "down-regulation of type IV restriction endodeoxyribonuclease activity" EXACT [] +synonym: "downregulation of type IV restriction endodeoxyribonuclease activity" EXACT [] +synonym: "inhibition of type IV restriction endodeoxyribonuclease activity" NARROW [] +synonym: "negative regulation of type IV restriction endodeoxyribonuclease activity" EXACT [GOC:dph, GOC:tb] +synonym: "type IV restriction endodeoxyribonuclease inhibitor" RELATED [] +synonym: "type IV restriction enzyme inhibitor" RELATED [] +is_a: GO:0032073 ! negative regulation of restriction endodeoxyribonuclease activity +is_a: GO:0032087 ! regulation of type IV site-specific deoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032067 ! type IV site-specific deoxyribonuclease activity +relationship: negatively_regulates GO:0032067 ! type IV site-specific deoxyribonuclease activity + +[Term] +id: GO:0032084 +name: regulation of type I site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah] +synonym: "regulation of type I restriction endodeoxyribonuclease activity" EXACT [GOC:dph] +synonym: "type I restriction endodeoxyribonuclease regulator" RELATED [] +synonym: "type I restriction enzyme regulator" RELATED [] +is_a: GO:0032072 ! regulation of restriction endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009035 ! type I site-specific deoxyribonuclease activity +relationship: regulates GO:0009035 ! type I site-specific deoxyribonuclease activity + +[Term] +id: GO:0032085 +name: regulation of type II site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah] +synonym: "regulation of type II restriction endodeoxyribonuclease activity" EXACT [GOC:dph] +synonym: "type II restriction endodeoxyribonuclease regulator" RELATED [] +synonym: "type II restriction enzyme regulator" RELATED [] +is_a: GO:0032072 ! regulation of restriction endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009036 ! type II site-specific deoxyribonuclease activity +relationship: regulates GO:0009036 ! type II site-specific deoxyribonuclease activity + +[Term] +id: GO:0032086 +name: regulation of type III site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity." [GOC:dph, GOC:mah] +synonym: "regulation of type III restriction endoribonuclease activity" EXACT [GOC:dph] +synonym: "type III restriction endodeoxyribonuclease regulator" RELATED [] +synonym: "type III restriction enzyme regulator" RELATED [] +is_a: GO:0032072 ! regulation of restriction endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015668 ! type III site-specific deoxyribonuclease activity +relationship: regulates GO:0015668 ! type III site-specific deoxyribonuclease activity + +[Term] +id: GO:0032087 +name: regulation of type IV site-specific deoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity." [GOC:mah] +synonym: "regulation of type IV restriction endodeoxyribonuclease activity" EXACT [GOC:dph] +synonym: "type IV restriction endodeoxyribonuclease regulator" RELATED [] +synonym: "type IV restriction enzyme regulator" RELATED [] +is_a: GO:0032072 ! regulation of restriction endodeoxyribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032067 ! type IV site-specific deoxyribonuclease activity +relationship: regulates GO:0032067 ! type IV site-specific deoxyribonuclease activity + +[Term] +id: GO:0032088 +name: negative regulation of NF-kappaB transcription factor activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb] +synonym: "inhibition of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] +synonym: "NF-kappaB inhibitor" RELATED [] +is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity + +[Term] +id: GO:0032089 +name: NACHT domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs." [GOC:rl] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0032090 +name: Pyrin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain." [GOC:rl] +synonym: "DAPIN domain binding" EXACT [] +synonym: "PAAD domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0032091 +name: negative regulation of protein binding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." [GOC:mah] +synonym: "down regulation of protein binding" EXACT [] +synonym: "down-regulation of protein binding" EXACT [] +synonym: "downregulation of protein binding" EXACT [] +synonym: "inhibition of protein binding" NARROW [] +is_a: GO:0043393 ! regulation of protein binding +is_a: GO:0051100 ! negative regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005515 ! protein binding +relationship: negatively_regulates GO:0005515 ! protein binding + +[Term] +id: GO:0032092 +name: positive regulation of protein binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein binding." [GOC:mah] +synonym: "activation of protein binding" NARROW [] +synonym: "stimulation of protein binding" NARROW [] +synonym: "up regulation of protein binding" EXACT [] +synonym: "up-regulation of protein binding" EXACT [] +synonym: "upregulation of protein binding" EXACT [] +is_a: GO:0043393 ! regulation of protein binding +is_a: GO:0051099 ! positive regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005515 ! protein binding +relationship: positively_regulates GO:0005515 ! protein binding + +[Term] +id: GO:0032093 +name: SAM domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes." [GOC:mcc, PMID:16337230] +synonym: "Sterile Alpha Motif domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0032094 +name: response to food +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." [GOC:add, ISBN:0721601464] +is_a: GO:0031667 ! response to nutrient levels +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0032095 +name: regulation of response to food +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to a food stimulus." [GOC:add] +is_a: GO:0032107 ! regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032094 ! response to food +relationship: regulates GO:0032094 ! response to food + +[Term] +id: GO:0032096 +name: negative regulation of response to food +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus." [GOC:add] +synonym: "down regulation of response to food" EXACT [] +synonym: "down-regulation of response to food" EXACT [] +synonym: "downregulation of response to food" EXACT [] +synonym: "inhibition of response to food" NARROW [] +is_a: GO:0032095 ! regulation of response to food +is_a: GO:0032108 ! negative regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032094 ! response to food +relationship: negatively_regulates GO:0032094 ! response to food + +[Term] +id: GO:0032097 +name: positive regulation of response to food +namespace: biological_process +def: "Any process that activates, maintains, or increases the rate of a response to a food stimulus." [GOC:add] +synonym: "activation of response to food" NARROW [] +synonym: "stimulation of response to food" NARROW [] +synonym: "up regulation of response to food" EXACT [] +synonym: "up-regulation of response to food" EXACT [] +synonym: "upregulation of response to food" EXACT [] +is_a: GO:0032095 ! regulation of response to food +is_a: GO:0032109 ! positive regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032094 ! response to food +relationship: positively_regulates GO:0032094 ! response to food + +[Term] +id: GO:0032098 +name: regulation of appetite +namespace: biological_process +def: "Any process which modulates appetite, the desire or physical craving for food." [GOC:add] +synonym: "regulation of hunger" RELATED [] +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0031667 ! response to nutrient levels + +[Term] +id: GO:0032099 +name: negative regulation of appetite +namespace: biological_process +def: "Any process that reduces appetite." [GOC:add] +synonym: "appetite suppression" RELATED [] +synonym: "down regulation of appetite" EXACT [] +synonym: "down-regulation of appetite" EXACT [] +synonym: "downregulation of appetite" EXACT [] +synonym: "inhibition of appetite" NARROW [] +synonym: "negative regulation of hunger" RELATED [] +is_a: GO:0032096 ! negative regulation of response to food +is_a: GO:0032098 ! regulation of appetite + +[Term] +id: GO:0032100 +name: positive regulation of appetite +namespace: biological_process +def: "Any process that increases appetite." [GOC:add] +synonym: "activation of appetite" NARROW [] +synonym: "appetite stimulation" RELATED [] +synonym: "positive regulation of hunger" RELATED [] +synonym: "stimulation of appetite" NARROW [] +synonym: "up regulation of appetite" EXACT [] +synonym: "up-regulation of appetite" EXACT [] +synonym: "upregulation of appetite" EXACT [] +is_a: GO:0032097 ! positive regulation of response to food +is_a: GO:0032098 ! regulation of appetite + +[Term] +id: GO:0032101 +name: regulation of response to external stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009605 ! response to external stimulus +relationship: regulates GO:0009605 ! response to external stimulus + +[Term] +id: GO:0032102 +name: negative regulation of response to external stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "down regulation of response to external stimulus" EXACT [] +synonym: "down-regulation of response to external stimulus" EXACT [] +synonym: "downregulation of response to external stimulus" EXACT [] +synonym: "inhibition of response to external stimulus" NARROW [] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0048585 ! negative regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009605 ! response to external stimulus +relationship: negatively_regulates GO:0009605 ! response to external stimulus + +[Term] +id: GO:0032103 +name: positive regulation of response to external stimulus +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "activation of response to external stimulus" NARROW [] +synonym: "stimulation of response to external stimulus" NARROW [] +synonym: "up regulation of response to external stimulus" EXACT [] +synonym: "up-regulation of response to external stimulus" EXACT [] +synonym: "upregulation of response to external stimulus" EXACT [] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009605 ! response to external stimulus +relationship: positively_regulates GO:0009605 ! response to external stimulus + +[Term] +id: GO:0032104 +name: regulation of response to extracellular stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus." [GOC:mah] +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009991 ! response to extracellular stimulus +relationship: regulates GO:0009991 ! response to extracellular stimulus + +[Term] +id: GO:0032105 +name: negative regulation of response to extracellular stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus." [GOC:mah] +synonym: "down regulation of response to extracellular stimulus" EXACT [] +synonym: "down-regulation of response to extracellular stimulus" EXACT [] +synonym: "downregulation of response to extracellular stimulus" EXACT [] +synonym: "inhibition of response to extracellular stimulus" NARROW [] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0032104 ! regulation of response to extracellular stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009991 ! response to extracellular stimulus +relationship: negatively_regulates GO:0009991 ! response to extracellular stimulus + +[Term] +id: GO:0032106 +name: positive regulation of response to extracellular stimulus +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of a response to an extracellular stimulus." [GOC:mah] +synonym: "activation of response to extracellular stimulus" NARROW [] +synonym: "stimulation of response to extracellular stimulus" NARROW [] +synonym: "up regulation of response to extracellular stimulus" EXACT [] +synonym: "up-regulation of response to extracellular stimulus" EXACT [] +synonym: "upregulation of response to extracellular stimulus" EXACT [] +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0032104 ! regulation of response to extracellular stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009991 ! response to extracellular stimulus +relationship: positively_regulates GO:0009991 ! response to extracellular stimulus + +[Term] +id: GO:0032107 +name: regulation of response to nutrient levels +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to nutrient levels." [GOC:mah] +is_a: GO:0032104 ! regulation of response to extracellular stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031667 ! response to nutrient levels +relationship: regulates GO:0031667 ! response to nutrient levels + +[Term] +id: GO:0032108 +name: negative regulation of response to nutrient levels +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels." [GOC:mah] +synonym: "down regulation of response to nutrient levels" EXACT [] +synonym: "down-regulation of response to nutrient levels" EXACT [] +synonym: "downregulation of response to nutrient levels" EXACT [] +synonym: "inhibition of response to nutrient levels" NARROW [] +is_a: GO:0032105 ! negative regulation of response to extracellular stimulus +is_a: GO:0032107 ! regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031667 ! response to nutrient levels +relationship: negatively_regulates GO:0031667 ! response to nutrient levels + +[Term] +id: GO:0032109 +name: positive regulation of response to nutrient levels +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a response to nutrient levels." [GOC:mah] +synonym: "activation of response to nutrient levels" NARROW [] +synonym: "stimulation of response to nutrient levels" NARROW [] +synonym: "up regulation of response to nutrient levels" EXACT [] +synonym: "up-regulation of response to nutrient levels" EXACT [] +synonym: "upregulation of response to nutrient levels" EXACT [] +is_a: GO:0032106 ! positive regulation of response to extracellular stimulus +is_a: GO:0032107 ! regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031667 ! response to nutrient levels +relationship: positively_regulates GO:0031667 ! response to nutrient levels + +[Term] +id: GO:0032110 +name: regulation of protein histidine kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein histidine kinase activity." [GOC:mah] +is_a: GO:0045859 ! regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004673 ! protein histidine kinase activity +relationship: regulates GO:0004673 ! protein histidine kinase activity + +[Term] +id: GO:0032111 +name: activation of protein histidine kinase activity +namespace: biological_process +def: "Any process that initiates the activity of an inactive protein histidine kinase." [GOC:mah] +synonym: "protein histidine kinase activator" RELATED [] +is_a: GO:0010864 ! positive regulation of protein histidine kinase activity +is_a: GO:0032147 ! activation of protein kinase activity + +[Term] +id: GO:0032112 +name: negative regulation of protein histidine kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity." [GOC:mah] +synonym: "down regulation of protein histidine kinase activity" EXACT [] +synonym: "down-regulation of protein histidine kinase activity" EXACT [] +synonym: "downregulation of protein histidine kinase activity" EXACT [] +synonym: "inhibition of protein histidine kinase activity" NARROW [] +synonym: "protein histidine kinase inhibitor" RELATED [] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:0032110 ! regulation of protein histidine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004673 ! protein histidine kinase activity +relationship: negatively_regulates GO:0004673 ! protein histidine kinase activity + +[Term] +id: GO:0032113 +name: regulation of carbohydrate phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate." [GOC:mah] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019203 ! carbohydrate phosphatase activity +relationship: regulates GO:0019203 ! carbohydrate phosphatase activity + +[Term] +id: GO:0032114 +name: regulation of glucose-6-phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate." [GOC:kp] +is_a: GO:0032113 ! regulation of carbohydrate phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004346 ! glucose-6-phosphatase activity +relationship: regulates GO:0004346 ! glucose-6-phosphatase activity + +[Term] +id: GO:0032115 +name: sorbose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction." [EC:1.1.1.289, RHEA:14609] +synonym: "D-glucitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.289] +synonym: "Sou1p" RELATED [EC:1.1.1.289] +xref: EC:1.1.1.289 +xref: KEGG_REACTION:R07346 +xref: MetaCyc:1.1.1.289-RXN +xref: RHEA:14609 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0032116 +name: SMC loading complex +namespace: cellular_component +def: "A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved." [GOC:curators, GOC:vw, PMID:10882066] +synonym: "chromatin loading complex" RELATED [] +synonym: "cohesin loading complex" NARROW [] +synonym: "SCC2/SCC4 loading complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032117 +name: horsetail-astral microtubule array +namespace: cellular_component +def: "An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement." [GOC:mah, PMID:16111942] +synonym: "HAA" EXACT [] +is_a: GO:0005818 ! aster +relationship: part_of GO:0030981 ! cortical microtubule cytoskeleton + +[Term] +id: GO:0032118 +name: horsetail-astral microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis." [GOC:mah] +synonym: "horsetail-astral microtubule array organization" EXACT [] +synonym: "horsetail-astral microtubule organisation" EXACT [GOC:mah] +synonym: "horsetail-astral microtubule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0030989 ! dynein-driven meiotic oscillatory nuclear movement + +[Term] +id: GO:0032119 +name: sequestering of zinc ion +namespace: biological_process +def: "The process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:mah] +is_a: GO:0051238 ! sequestering of metal ion +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0006882 ! cellular zinc ion homeostasis + +[Term] +id: GO:0032120 +name: ascospore-type prospore membrane formation +namespace: biological_process +alt_id: GO:0099097 +def: "The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed." [GOC:clt, PMID:27630265] +synonym: "ascospore-type prospore membrane assembly" RELATED [] +synonym: "forespore membrane biosynthesis" EXACT [] +synonym: "forespore membrane formation" EXACT [] +synonym: "FSM assembly" EXACT [] +synonym: "FSM biosynthesis" EXACT [] +synonym: "FSM formation" EXACT [] +synonym: "prospore membrane biogenesis" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0071709 ! membrane assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0031321 ! ascospore-type prospore assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14712 xsd:anyURI + +[Term] +id: GO:0032121 +name: meiotic attachment of telomeric heterochromatin to spindle pole body +namespace: biological_process +def: "The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation." [GOC:pr, PMID:16615890] +synonym: "attachment of telomeres to spindle pole body" BROAD [] +synonym: "attachment of telomeric chromatin to spindle pole body" BROAD [] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0045141 ! meiotic telomere clustering + +[Term] +id: GO:0032122 +name: oral apparatus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans." [PMID:10503189, PMID:6414830] +synonym: "oral apparatus morphogenesis" RELATED [] +synonym: "oral apparatus organisation" EXACT [GOC:mah] +synonym: "oral apparatus organization and biogenesis" RELATED [GOC:mah] +synonym: "stomatogenesis" RELATED [] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0032123 +name: deep fiber +namespace: cellular_component +def: "Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm." [PMID:10503189] +synonym: "deep fibre" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0031912 ! oral apparatus + +[Term] +id: GO:0032124 +name: macronucleus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus." [GOC:dph, GOC:jl, GOC:mah, PMID:10503190] +synonym: "macronuclear organization" EXACT [] +synonym: "macronuclear organization and biogenesis" RELATED [GOC:mah] +synonym: "macronucleus organisation" EXACT [GOC:mah] +is_a: GO:0006997 ! nucleus organization + +[Term] +id: GO:0032125 +name: micronucleus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus." [GOC:dph, GOC:jl, GOC:mah, PMID:10503190] +synonym: "micronuclear organization" EXACT [] +synonym: "micronuclear organization and biogenesis" RELATED [GOC:mah] +synonym: "micronucleus organisation" EXACT [GOC:mah] +is_a: GO:0006997 ! nucleus organization + +[Term] +id: GO:0032126 +name: eisosome +namespace: cellular_component +def: "A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization." [GOC:al, GOC:vw, PMID:16496001, PMID:22368779] +xref: Wikipedia:Eisosome +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0032127 +name: dense core granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a dense core granule." [GOC:mah] +synonym: "dense core vesicle membrane" EXACT [GOC:kmv] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0031045 ! dense core granule + +[Term] +id: GO:0032129 +name: histone deacetylase activity (H3-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein." [EC:3.5.1.17, RHEA:24548] +is_a: GO:0004407 ! histone deacetylase activity +relationship: part_of GO:0061647 ! histone H3-K9 modification +relationship: part_of GO:1990619 ! histone H3-K9 deacetylation + +[Term] +id: GO:0032130 +name: medial membrane band assembly +namespace: biological_process +def: "The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring." [PMID:15517003] +synonym: "medial membrane band formation" RELATED [gOC:dph] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:1902410 ! mitotic cytokinetic process + +[Term] +id: GO:0032131 +name: alkylated DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with alkylated residues in DNA." [GOC:mah] +is_a: GO:0003684 ! damaged DNA binding + +[Term] +id: GO:0032132 +name: O6-alkylguanine-DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with O6-alkylguanine adducts in DNA." [GOC:mah, PMID:16679453] +is_a: GO:0032131 ! alkylated DNA binding + +[Term] +id: GO:0032133 +name: chromosome passenger complex +namespace: cellular_component +def: "A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin." [GOC:vw, PMID:16824200, PMID:19570910] +synonym: "chromosomal passenger complex" EXACT [GOC:mcc] +synonym: "CPC" BROAD [GOC:mah] +synonym: "CPC complex" EXACT [GOC:vw] +is_a: GO:0005875 ! microtubule associated complex + +[Term] +id: GO:0032135 +name: DNA insertion or deletion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions." [GOC:vk] +synonym: "DNA insertion binding" NARROW [] +synonym: "insertion binding" EXACT [] +is_a: GO:0030983 ! mismatched DNA binding + +[Term] +id: GO:0032136 +name: adenine/cytosine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair." [GOC:vk] +synonym: "A/C mispair binding" EXACT [GOC:bf] +synonym: "C/A mispair binding" EXACT [GOC:bf] +synonym: "cytosine/adenine mispair binding" RELATED [GOC:bf] +is_a: GO:0030983 ! mismatched DNA binding + +[Term] +id: GO:0032137 +name: guanine/thymine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair." [GOC:vk] +synonym: "G/T mispair binding" EXACT [GOC:bf] +synonym: "T/G mispair binding" EXACT [GOC:bf] +synonym: "thymine/guanine mispair binding" EXACT [GOC:bf] +is_a: GO:0030983 ! mismatched DNA binding + +[Term] +id: GO:0032138 +name: single base insertion or deletion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion." [GOC:vk] +synonym: "single base insertion binding" NARROW [] +is_a: GO:0032135 ! DNA insertion or deletion binding + +[Term] +id: GO:0032139 +name: dinucleotide insertion or deletion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion." [GOC:vk] +synonym: "dinucleotide insertion binding" NARROW [] +is_a: GO:0032135 ! DNA insertion or deletion binding + +[Term] +id: GO:0032140 +name: single adenine insertion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine." [GOC:mah, GOC:vk] +is_a: GO:0032138 ! single base insertion or deletion binding + +[Term] +id: GO:0032141 +name: single cytosine insertion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine." [GOC:mah, GOC:vk] +is_a: GO:0032138 ! single base insertion or deletion binding + +[Term] +id: GO:0032142 +name: single guanine insertion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine." [GOC:mah, GOC:vk] +is_a: GO:0032138 ! single base insertion or deletion binding + +[Term] +id: GO:0032143 +name: single thymine insertion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine." [GOC:mah, GOC:vk] +is_a: GO:0032138 ! single base insertion or deletion binding + +[Term] +id: GO:0032144 +name: 4-aminobutyrate transaminase complex +namespace: cellular_component +def: "A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity." [GOC:mah, PMID:15528998] +synonym: "ABAT complex" EXACT [] +synonym: "GABA transaminase complex" EXACT [] +synonym: "GABA-T complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032145 +name: succinate-semialdehyde dehydrogenase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with succinate-semialdehyde dehydrogenase." [GOC:mah] +synonym: "succinic semialdehyde dehydrogenase binding" EXACT [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0032147 +name: activation of protein kinase activity +namespace: biological_process +def: "Any process that initiates the activity of an inactive protein kinase." [GOC:mah] +synonym: "protein kinase activation" RELATED [] +is_a: GO:0045860 ! positive regulation of protein kinase activity + +[Term] +id: GO:0032148 +name: activation of protein kinase B activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme protein kinase B." [GOC:pg] +synonym: "protein kinase B activation" EXACT [] +is_a: GO:0032147 ! activation of protein kinase activity + +[Term] +id: GO:0032149 +name: response to rhamnose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus." [GOC:mlg] +synonym: "response to L-rhamnose stimulus" NARROW [] +synonym: "response to rhamnose stimulus" EXACT [GOC:dos] +is_a: GO:0009746 ! response to hexose + +[Term] +id: GO:0032150 +name: ubiquinone biosynthetic process from chorismate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate." [GOC:mah, PMID:11583838] +is_a: GO:0006744 ! ubiquinone biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0032151 +name: mitotic septin complex +namespace: cellular_component +def: "A heterooligomeric septin complex that acts during mitotic cell division." [GOC:krc, PMID:16009555] +is_a: GO:0031105 ! septin complex + +[Term] +id: GO:0032152 +name: meiotic septin complex +namespace: cellular_component +def: "A heterooligomeric septin complex that acts during meiotic cell division." [GOC:krc, PMID:16009555] +is_a: GO:0031105 ! septin complex + +[Term] +id: GO:0032153 +name: cell division site +namespace: cellular_component +def: "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles." [GOC:bf, GOC:imk, GOC:krc, GOC:ns, PMID:12101122, PMID:15380095, PMID:16983191, PMID:18165305] +comment: Note that this term refers to the future site of division in a cell that has not yet divided. +subset: goslim_pir +synonym: "cell division plane" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0032154 +name: cleavage furrow +namespace: cellular_component +def: "The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm." [GOC:vw, ISBN:0805319409] +comment: While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists. +xref: Wikipedia:Cleavage_furrow +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0032155 +name: obsolete cell division site part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "cell division plane part" EXACT [] +is_obsolete: true +consider: GO:0032153 + +[Term] +id: GO:0032156 +name: septin cytoskeleton +namespace: cellular_component +def: "The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes." [GOC:mah] +is_a: GO:0005856 ! cytoskeleton + +[Term] +id: GO:0032157 +name: prospore contractile ring +namespace: cellular_component +def: "A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis." [GOC:krc, PMID:16009555] +synonym: "actomyosin ring" RELATED [] +synonym: "cytokinetic ring" RELATED [] +synonym: "meiotic contractile ring" RELATED [] +is_a: GO:0110086 ! meiotic actomyosin contractile ring +intersection_of: GO:0005826 ! actomyosin contractile ring +intersection_of: part_of GO:0042764 ! ascospore-type prospore +relationship: part_of GO:0042764 ! ascospore-type prospore + +[Term] +id: GO:0032158 +name: septin band +namespace: cellular_component +def: "A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:krc, PMID:16151244] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032156 ! septin cytoskeleton + +[Term] +id: GO:0032159 +name: septin cap +namespace: cellular_component +def: "A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] +is_a: GO:0032156 ! septin cytoskeleton +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0032160 +name: septin filament array +namespace: cellular_component +def: "Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans." [GOC:krc, PMID:16151244] +synonym: "septin bar" RELATED [] +is_a: GO:0032156 ! septin cytoskeleton +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0032161 +name: cleavage apparatus septin structure +namespace: cellular_component +def: "Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis." [GOC:krc, PMID:12101122, PMID:15774761, PMID:16009555] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005938 ! cell cortex +relationship: part_of GO:0032153 ! cell division site +relationship: part_of GO:0032156 ! septin cytoskeleton + +[Term] +id: GO:0032162 +name: mating projection septin band +namespace: cellular_component +def: "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection)." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0032158 ! septin band +intersection_of: GO:0032158 ! septin band +intersection_of: part_of GO:0005937 ! mating projection +relationship: part_of GO:0005937 ! mating projection + +[Term] +id: GO:0032163 +name: hyphal septin band +namespace: cellular_component +def: "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0032158 ! septin band + +[Term] +id: GO:0032164 +name: hyphal septin cap +namespace: cellular_component +def: "A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] +is_a: GO:0032159 ! septin cap + +[Term] +id: GO:0032165 +name: prospore septin filament array +namespace: cellular_component +def: "Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation." [GOC:krc, PMID:16151244] +is_a: GO:0032160 ! septin filament array + +[Term] +id: GO:0032166 +name: chlamydospore septin filament array +namespace: cellular_component +def: "Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation." [GOC:krc, PMID:16151244] +is_a: GO:0032160 ! septin filament array + +[Term] +id: GO:0032167 +name: obsolete septin patch +namespace: cellular_component +def: "OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis." [PMID:16009555] +comment: This term was made obsolete because it was added in error; it does not refer to a normal subcellular structure. +synonym: "septin patch" EXACT [] +is_obsolete: true + +[Term] +id: GO:0032168 +name: hyphal septin ring +namespace: cellular_component +def: "A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0005940 ! septin ring + +[Term] +id: GO:0032169 +name: prospore septin ring +namespace: cellular_component +def: "A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0005940 ! septin ring +is_a: GO:0032161 ! cleavage apparatus septin structure +intersection_of: GO:0005940 ! septin ring +intersection_of: part_of GO:0042764 ! ascospore-type prospore +relationship: part_of GO:0042764 ! ascospore-type prospore + +[Term] +id: GO:0032170 +name: pseudohyphal septin ring +namespace: cellular_component +def: "A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0005940 ! septin ring + +[Term] +id: GO:0032171 +name: germ tube septin cap +namespace: cellular_component +def: "A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] +is_a: GO:0032159 ! septin cap +intersection_of: GO:0032159 ! septin cap +intersection_of: part_of GO:0032179 ! germ tube +relationship: part_of GO:0032179 ! germ tube + +[Term] +id: GO:0032172 +name: germ tube septin ring +namespace: cellular_component +def: "A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, PMID:16151244] +is_a: GO:0005940 ! septin ring +intersection_of: GO:0005940 ! septin ring +intersection_of: part_of GO:0032179 ! germ tube +relationship: part_of GO:0032179 ! germ tube + +[Term] +id: GO:0032173 +name: septin collar +namespace: cellular_component +def: "A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell." [GOC:krc, PMID:16009555, PMID:16151244] +is_a: GO:0032156 ! septin cytoskeleton +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0032174 +name: cellular bud neck septin collar +namespace: cellular_component +def: "A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck." [GOC:krc, PMID:16009555] +is_a: GO:0000399 ! cellular bud neck septin structure +is_a: GO:0032161 ! cleavage apparatus septin structure +is_a: GO:0032173 ! septin collar +intersection_of: GO:0032173 ! septin collar +intersection_of: part_of GO:0005935 ! cellular bud neck + +[Term] +id: GO:0032175 +name: mating projection septin ring +namespace: cellular_component +def: "A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip." [GOC:krc, GOC:mah, PMID:16151244] +is_a: GO:0005940 ! septin ring +intersection_of: GO:0005940 ! septin ring +intersection_of: part_of GO:0005937 ! mating projection +relationship: part_of GO:0005937 ! mating projection + +[Term] +id: GO:0032176 +name: split septin rings +namespace: cellular_component +def: "A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well." [GOC:krc, PMID:16009555, PMID:16151244] +is_a: GO:0032156 ! septin cytoskeleton +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0032177 +name: cellular bud neck split septin rings +namespace: cellular_component +def: "Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated." [GOC:krc, PMID:16009555] +is_a: GO:0000399 ! cellular bud neck septin structure +is_a: GO:0032161 ! cleavage apparatus septin structure +is_a: GO:0032176 ! split septin rings +intersection_of: GO:0032176 ! split septin rings +intersection_of: part_of GO:0005935 ! cellular bud neck + +[Term] +id: GO:0032178 +name: medial membrane band +namespace: cellular_component +def: "A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum." [PMID:15517003] +synonym: "sterol-rich membrane band" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0032153 ! cell division site + +[Term] +id: GO:0032179 +name: germ tube +namespace: cellular_component +def: "The slender tubular outgrowth first produced by most spores in germination." [ISBN:0877799148] +subset: goslim_pir +xref: Wikipedia:Germ_tube +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0032180 +name: ubiquinone biosynthetic process from tyrosine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate." [GOC:mah, PMID:11583838] +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0006744 ! ubiquinone biosynthetic process + +[Term] +id: GO:0032181 +name: dinucleotide repeat insertion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats." [GOC:mah, GOC:vk] +is_a: GO:0032139 ! dinucleotide insertion or deletion binding + +[Term] +id: GO:0032182 +name: ubiquitin-like protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_yeast +synonym: "small conjugating protein binding" EXACT [GOC:dph] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0032183 +name: SUMO binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO." [GOC:mah] +synonym: "Smt3 binding" RELATED [] +synonym: "Smt3 monomer binding" NARROW [] +is_a: GO:0032182 ! ubiquitin-like protein binding + +[Term] +id: GO:0032184 +name: SUMO polymer binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO." [GOC:mah] +synonym: "Smt3 polymer binding" EXACT [] +is_a: GO:0032183 ! SUMO binding + +[Term] +id: GO:0032185 +name: septin cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] +synonym: "septin cytoskeleton organisation" EXACT [GOC:mah] +synonym: "septin cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0032186 +name: cellular bud neck septin ring organization +namespace: biological_process +def: "Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck." [GOC:mah] +synonym: "cellular bud neck septin ring organisation" EXACT [GOC:mah] +is_a: GO:0031106 ! septin ring organization +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0000281 ! mitotic cytokinesis +relationship: part_of GO:0007105 ! cytokinesis, site selection + +[Term] +id: GO:0032187 +name: actomyosin contractile ring localization +namespace: biological_process +def: "The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle." [GOC:mah] +synonym: "contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:mah] +synonym: "contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +is_a: GO:0036214 ! contractile ring localization + +[Term] +id: GO:0032188 +name: establishment of actomyosin contractile ring localization +namespace: biological_process +def: "The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis." [GOC:mah] +synonym: "actomyosin ring positioning" RELATED [GOC:mah] +synonym: "contractile ring positioning" BROAD [GOC:mah] +synonym: "cytokinesis site selection by contractile ring positioning" EXACT [GOC:mah, GOC:vw] +synonym: "establishment of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:mah] +synonym: "establishment of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "establishment of contractile ring localization involved in cytokinesis during cell cycle" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032187 ! actomyosin contractile ring localization +relationship: part_of GO:0007105 ! cytokinesis, site selection + +[Term] +id: GO:0032189 +name: maintenance of actomyosin contractile ring localization +namespace: biological_process +def: "Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere." [GOC:mah] +synonym: "cytokinetic ring anchoring" RELATED [] +synonym: "maintenance of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:mah] +synonym: "maintenance of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "maintenance of contractile ring localization involved in cytokinesis during cell cycle" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032187 ! actomyosin contractile ring localization +relationship: part_of GO:0031566 ! actomyosin contractile ring maintenance + +[Term] +id: GO:0032190 +name: acrosin binding +namespace: molecular_function +alt_id: GO:0032191 +alt_id: GO:0032192 +def: "Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities." [GOC:mah, PMID:12398221] +synonym: "acrosin heavy chain binding" NARROW [] +synonym: "acrosin light chain binding" NARROW [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0032193 +name: ubiquinone biosynthetic process via 2-polyprenylphenol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol." [GOC:mah, PMID:11583838] +is_a: GO:0006744 ! ubiquinone biosynthetic process + +[Term] +id: GO:0032194 +name: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate." [GOC:mah, PMID:11583838] +is_a: GO:0006744 ! ubiquinone biosynthetic process + +[Term] +id: GO:0032195 +name: post-lysosomal vacuole +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis." [GOC:pf, PMID:9276759, PMID:9394012] +synonym: "post-lysosome" EXACT [GOC:dph] +is_a: GO:0005773 ! vacuole +is_a: GO:0030139 ! endocytic vesicle + +[Term] +id: GO:0032196 +name: transposition +namespace: biological_process +def: "Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites." [GOC:jp, ISBN:1555812090] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_yeast +xref: Wikipedia:Transposon +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0032197 +name: transposition, RNA-mediated +namespace: biological_process +alt_id: GO:0006319 +alt_id: GO:0006320 +alt_id: GO:0006321 +alt_id: GO:0006322 +def: "Any process involved in a type of transpositional recombination which occurs via an RNA intermediate." [GOC:jp, ISBN:1555812090] +synonym: "Class I transposition" EXACT [] +synonym: "retrotransposition" EXACT [] +synonym: "retrotransposon transposition" EXACT [] +synonym: "RNA-mediated transposition" EXACT [GOC:dph, GOC:tb] +synonym: "Tf transposition" NARROW [] +synonym: "Ty element transposition" NARROW [] +synonym: "Ty1 element transposition" NARROW [] +synonym: "Ty2 element transposition" NARROW [] +synonym: "Ty3 element transposition" NARROW [] +xref: Wikipedia:Transposon##Class_I\:_Retrotransposons +is_a: GO:0032196 ! transposition + +[Term] +id: GO:0032198 +name: MITE transposition +namespace: biological_process +def: "Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs)." [GOC:jp, ISBN:1555812090] +synonym: "Class III transposition" EXACT [] +is_a: GO:0032196 ! transposition + +[Term] +id: GO:0032199 +name: reverse transcription involved in RNA-mediated transposition +namespace: biological_process +def: "The synthesis of DNA from an RNA transposon intermediate." [GOC:jp, GOC:txnOH, ISBN:1555812090] +synonym: "reverse transcription during retrotransposition" EXACT [] +is_a: GO:0001171 ! reverse transcription +intersection_of: GO:0001171 ! reverse transcription +intersection_of: part_of GO:0032197 ! transposition, RNA-mediated +relationship: part_of GO:0032197 ! transposition, RNA-mediated + +[Term] +id: GO:0032200 +name: telomere organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pombe +subset: goslim_yeast +synonym: "chromosome organization, telomeric" EXACT [] +synonym: "organization of chromosome, telomeric region" EXACT [] +synonym: "telomere organisation" EXACT [GOC:mah] +synonym: "telomere organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0032201 +name: telomere maintenance via semi-conservative replication +namespace: biological_process +def: "The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication." [GOC:BHF, GOC:BHF_telomere, GOC:rl, GOC:vw, PMID:16598261] +synonym: "equal telomere replication" RELATED [] +synonym: "telomeric fork progression" NARROW [] +synonym: "telomeric replication fork progression" NARROW [] +is_a: GO:0000723 ! telomere maintenance +is_a: GO:0019725 ! cellular homeostasis +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0033260 ! nuclear DNA replication + +[Term] +id: GO:0032202 +name: telomere assembly +namespace: biological_process +def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins." [GOC:mah, GOC:ns, PMID:11902675, PMID:8622671] +synonym: "telomere formation" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0032200 ! telomere organization + +[Term] +id: GO:0032203 +name: telomere formation via telomerase +namespace: biological_process +def: "A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme." [GOC:cjm, GOC:ns, PMID:11902675, PMID:8622671] +is_a: GO:0032202 ! telomere assembly +relationship: has_part GO:0003720 ! telomerase activity +relationship: has_part GO:1905324 ! telomere-telomerase complex assembly + +[Term] +id: GO:0032204 +name: regulation of telomere maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000723 ! telomere maintenance +relationship: regulates GO:0000723 ! telomere maintenance + +[Term] +id: GO:0032205 +name: negative regulation of telomere maintenance +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] +synonym: "down regulation of telomere maintenance" EXACT [] +synonym: "down-regulation of telomere maintenance" EXACT [] +synonym: "downregulation of telomere maintenance" EXACT [] +synonym: "inhibition of telomere maintenance" NARROW [] +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000723 ! telomere maintenance +relationship: negatively_regulates GO:0000723 ! telomere maintenance + +[Term] +id: GO:0032206 +name: positive regulation of telomere maintenance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] +synonym: "activation of telomere maintenance" NARROW [] +synonym: "stimulation of telomere maintenance" NARROW [] +synonym: "up regulation of telomere maintenance" EXACT [] +synonym: "up-regulation of telomere maintenance" EXACT [] +synonym: "upregulation of telomere maintenance" EXACT [] +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000723 ! telomere maintenance +relationship: positively_regulates GO:0000723 ! telomere maintenance + +[Term] +id: GO:0032207 +name: regulation of telomere maintenance via recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] +is_a: GO:0000019 ! regulation of mitotic recombination +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:0072695 ! regulation of DNA recombination at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000722 ! telomere maintenance via recombination +relationship: regulates GO:0000722 ! telomere maintenance via recombination + +[Term] +id: GO:0032208 +name: negative regulation of telomere maintenance via recombination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] +synonym: "down regulation of telomere maintenance via recombination" EXACT [] +synonym: "down-regulation of telomere maintenance via recombination" EXACT [] +synonym: "downregulation of telomere maintenance via recombination" EXACT [] +synonym: "inhibition of telomere maintenance via recombination" NARROW [] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:0032207 ! regulation of telomere maintenance via recombination +is_a: GO:0045950 ! negative regulation of mitotic recombination +is_a: GO:0048239 ! negative regulation of DNA recombination at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000722 ! telomere maintenance via recombination +relationship: negatively_regulates GO:0000722 ! telomere maintenance via recombination + +[Term] +id: GO:0032209 +name: positive regulation of telomere maintenance via recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] +synonym: "activation of telomere maintenance via recombination" NARROW [] +synonym: "stimulation of telomere maintenance via recombination" NARROW [] +synonym: "up regulation of telomere maintenance via recombination" EXACT [] +synonym: "up-regulation of telomere maintenance via recombination" EXACT [] +synonym: "upregulation of telomere maintenance via recombination" EXACT [] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:0032207 ! regulation of telomere maintenance via recombination +is_a: GO:0045951 ! positive regulation of mitotic recombination +is_a: GO:0072696 ! positive regulation of DNA recombination at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000722 ! telomere maintenance via recombination +relationship: positively_regulates GO:0000722 ! telomere maintenance via recombination + +[Term] +id: GO:0032210 +name: regulation of telomere maintenance via telomerase +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] +is_a: GO:1904356 ! regulation of telomere maintenance via telomere lengthening +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007004 ! telomere maintenance via telomerase +relationship: regulates GO:0007004 ! telomere maintenance via telomerase + +[Term] +id: GO:0032211 +name: negative regulation of telomere maintenance via telomerase +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] +synonym: "down regulation of telomere maintenance via telomerase activity" EXACT [] +synonym: "down-regulation of telomere maintenance via telomerase activity" EXACT [] +synonym: "downregulation of telomere maintenance via telomerase activity" EXACT [] +synonym: "inhibition of telomere maintenance via telomerase" NARROW [] +is_a: GO:0032210 ! regulation of telomere maintenance via telomerase +is_a: GO:1904357 ! negative regulation of telomere maintenance via telomere lengthening +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007004 ! telomere maintenance via telomerase +relationship: negatively_regulates GO:0007004 ! telomere maintenance via telomerase + +[Term] +id: GO:0032212 +name: positive regulation of telomere maintenance via telomerase +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] +synonym: "activation of telomere maintenance via telomerase" NARROW [] +synonym: "stimulation of telomere maintenance via telomerase" NARROW [] +synonym: "up regulation of telomere maintenance via telomerase activity" EXACT [] +synonym: "up-regulation of telomere maintenance via telomerase activity" EXACT [] +synonym: "upregulation of telomere maintenance via telomerase activity" EXACT [] +is_a: GO:0032210 ! regulation of telomere maintenance via telomerase +is_a: GO:1904358 ! positive regulation of telomere maintenance via telomere lengthening +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007004 ! telomere maintenance via telomerase +relationship: positively_regulates GO:0007004 ! telomere maintenance via telomerase + +[Term] +id: GO:0032213 +name: regulation of telomere maintenance via semi-conservative replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:0033262 ! regulation of nuclear cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032201 ! telomere maintenance via semi-conservative replication +relationship: regulates GO:0032201 ! telomere maintenance via semi-conservative replication + +[Term] +id: GO:0032214 +name: negative regulation of telomere maintenance via semi-conservative replication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] +synonym: "down regulation of telomere maintenance via semi-conservative replication" EXACT [] +synonym: "down-regulation of telomere maintenance via semi-conservative replication" EXACT [] +synonym: "downregulation of telomere maintenance via semi-conservative replication" EXACT [] +synonym: "inhibition of telomere maintenance via semi-conservative replication" NARROW [] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:0032213 ! regulation of telomere maintenance via semi-conservative replication +is_a: GO:1902576 ! negative regulation of nuclear cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032201 ! telomere maintenance via semi-conservative replication +relationship: negatively_regulates GO:0032201 ! telomere maintenance via semi-conservative replication + +[Term] +id: GO:0032215 +name: positive regulation of telomere maintenance via semi-conservative replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] +synonym: "activation of telomere maintenance via semi-conservative replication" NARROW [] +synonym: "stimulation of telomere maintenance via semi-conservative replication" NARROW [] +synonym: "up regulation of telomere maintenance via semi-conservative replication" EXACT [] +synonym: "up-regulation of telomere maintenance via semi-conservative replication" EXACT [] +synonym: "upregulation of telomere maintenance via semi-conservative replication" EXACT [] +is_a: GO:0010571 ! positive regulation of nuclear cell cycle DNA replication +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:0032213 ! regulation of telomere maintenance via semi-conservative replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032201 ! telomere maintenance via semi-conservative replication +relationship: positively_regulates GO:0032201 ! telomere maintenance via semi-conservative replication + +[Term] +id: GO:0032216 +name: glucosaminyl-phosphatidylinositol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA." [Reactome:R-HSA-162683] +synonym: "glucosaminyl-phosphotidylinositol O-acyltransferase activity" EXACT [] +synonym: "GPI-inositol acyltransferase" RELATED [] +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0032217 +name: riboflavin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239] +synonym: "riboflavin transporter activity" RELATED [] +xref: Reactome:R-HSA-3165230 "SLC52A1,2,3 transport RIB from extracellular region to cytosol" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0032218 ! riboflavin transport + +[Term] +id: GO:0032218 +name: riboflavin transport +namespace: biological_process +def: "The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0032219 +name: cell wall macromolecule catabolic process involved in cytogamy +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy." [GOC:mah] +synonym: "cell wall macromolecule catabolic process during cytogamy" RELATED [GOC:dph, GOC:tb] +is_a: GO:0016998 ! cell wall macromolecule catabolic process +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0016998 ! cell wall macromolecule catabolic process +intersection_of: part_of GO:0000755 ! cytogamy +relationship: part_of GO:0000755 ! cytogamy + +[Term] +id: GO:0032220 +name: plasma membrane fusion involved in cytogamy +namespace: biological_process +alt_id: GO:0070872 +def: "The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy." [GOC:mah, PMID:29134248] +synonym: "plasma membrane fusion during cytogamy" RELATED [GOC:dph, GOC:tb] +synonym: "plasma membrane organization involved in conjugation with cellular fusion" EXACT [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0045026 ! plasma membrane fusion +intersection_of: GO:0045026 ! plasma membrane fusion +intersection_of: part_of GO:0000755 ! cytogamy +relationship: part_of GO:0000755 ! cytogamy +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16258 xsd:anyURI +created_by: mah +creation_date: 2009-08-20T02:24:56Z + +[Term] +id: GO:0032221 +name: Rpd3S complex +namespace: cellular_component +alt_id: GO:0000509 +def: "A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species)." [GOC:vw, PMID:12773392, PMID:17450151] +synonym: "Clr6 histone deacetylase complex II'" EXACT [GOC:vw] +synonym: "Clr6S complex" EXACT [PMID:19040720] +synonym: "Rpd3C(S)" EXACT [] +is_a: GO:0070822 ! Sin3-type complex + +[Term] +id: GO:0032222 +name: regulation of synaptic transmission, cholinergic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007271 ! synaptic transmission, cholinergic +relationship: regulates GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0032223 +name: negative regulation of synaptic transmission, cholinergic +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] +synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] +synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] +synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] +synonym: "inhibition of synaptic transmission, cholinergic" NARROW [] +is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic +is_a: GO:0050805 ! negative regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic +relationship: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0032224 +name: positive regulation of synaptic transmission, cholinergic +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] +synonym: "activation of synaptic transmission, cholinergic" NARROW [] +synonym: "stimulation of synaptic transmission, cholinergic" NARROW [] +synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] +synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] +synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] +is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic +is_a: GO:0050806 ! positive regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007271 ! synaptic transmission, cholinergic +relationship: positively_regulates GO:0007271 ! synaptic transmission, cholinergic + +[Term] +id: GO:0032225 +name: regulation of synaptic transmission, dopaminergic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001963 ! synaptic transmission, dopaminergic +relationship: regulates GO:0001963 ! synaptic transmission, dopaminergic + +[Term] +id: GO:0032226 +name: positive regulation of synaptic transmission, dopaminergic +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] +synonym: "activation of synaptic transmission, dopaminergic" NARROW [] +synonym: "stimulation of synaptic transmission, dopaminergic" NARROW [] +synonym: "up regulation of synaptic transmission, dopaminergic" EXACT [] +synonym: "up-regulation of synaptic transmission, dopaminergic" EXACT [] +synonym: "upregulation of synaptic transmission, dopaminergic" EXACT [] +is_a: GO:0032225 ! regulation of synaptic transmission, dopaminergic +is_a: GO:0050806 ! positive regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001963 ! synaptic transmission, dopaminergic +relationship: positively_regulates GO:0001963 ! synaptic transmission, dopaminergic + +[Term] +id: GO:0032227 +name: negative regulation of synaptic transmission, dopaminergic +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] +synonym: "down regulation of synaptic transmission, dopaminergic" EXACT [] +synonym: "down-regulation of synaptic transmission, dopaminergic" EXACT [] +synonym: "downregulation of synaptic transmission, dopaminergic" EXACT [] +synonym: "inhibition of synaptic transmission, dopaminergic" NARROW [] +is_a: GO:0032225 ! regulation of synaptic transmission, dopaminergic +is_a: GO:0050805 ! negative regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001963 ! synaptic transmission, dopaminergic +relationship: negatively_regulates GO:0001963 ! synaptic transmission, dopaminergic + +[Term] +id: GO:0032228 +name: regulation of synaptic transmission, GABAergic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051932 ! synaptic transmission, GABAergic +relationship: regulates GO:0051932 ! synaptic transmission, GABAergic + +[Term] +id: GO:0032229 +name: negative regulation of synaptic transmission, GABAergic +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] +synonym: "down regulation of synaptic transmission, GABAergic" EXACT [] +synonym: "down-regulation of synaptic transmission, GABAergic" EXACT [] +synonym: "downregulation of synaptic transmission, GABAergic" EXACT [] +synonym: "inhibition of synaptic transmission, GABAergic" NARROW [] +is_a: GO:0032228 ! regulation of synaptic transmission, GABAergic +is_a: GO:0050805 ! negative regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051932 ! synaptic transmission, GABAergic +relationship: negatively_regulates GO:0051932 ! synaptic transmission, GABAergic + +[Term] +id: GO:0032230 +name: positive regulation of synaptic transmission, GABAergic +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] +synonym: "activation of synaptic transmission, GABAergic" NARROW [] +synonym: "stimulation of synaptic transmission, GABAergic" NARROW [] +synonym: "up regulation of synaptic transmission, GABAergic" EXACT [] +synonym: "up-regulation of synaptic transmission, GABAergic" EXACT [] +synonym: "upregulation of synaptic transmission, GABAergic" EXACT [] +is_a: GO:0032228 ! regulation of synaptic transmission, GABAergic +is_a: GO:0050806 ! positive regulation of synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051932 ! synaptic transmission, GABAergic +relationship: positively_regulates GO:0051932 ! synaptic transmission, GABAergic + +[Term] +id: GO:0032231 +name: regulation of actin filament bundle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] +synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of actin filament bundle formation" RELATED [GOC:dph] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0110053 ! regulation of actin filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051017 ! actin filament bundle assembly +relationship: regulates GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0032232 +name: negative regulation of actin filament bundle assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] +synonym: "down regulation of actin filament bundle formation" EXACT [] +synonym: "down-regulation of actin filament bundle formation" EXACT [] +synonym: "downregulation of actin filament bundle formation" EXACT [] +synonym: "inhibition of actin filament bundle formation" NARROW [] +is_a: GO:0032231 ! regulation of actin filament bundle assembly +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051017 ! actin filament bundle assembly +relationship: negatively_regulates GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0032233 +name: positive regulation of actin filament bundle assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] +synonym: "activation of actin filament bundle formation" NARROW [] +synonym: "stimulation of actin filament bundle formation" NARROW [] +synonym: "up regulation of actin filament bundle formation" EXACT [] +synonym: "up-regulation of actin filament bundle formation" EXACT [] +synonym: "upregulation of actin filament bundle formation" EXACT [] +is_a: GO:0032231 ! regulation of actin filament bundle assembly +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051017 ! actin filament bundle assembly +relationship: positively_regulates GO:0051017 ! actin filament bundle assembly + +[Term] +id: GO:0032234 +name: obsolete regulation of calcium ion transport via store-operated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "regulation of calcium ion transport via store-operated calcium channel activity" EXACT [] +synonym: "regulation of calcium transport via store-operated calcium channel" EXACT [] +synonym: "regulation of store-operated calcium channel activity" EXACT [] +is_obsolete: true +consider: GO:0015279 + +[Term] +id: GO:0032235 +name: obsolete negative regulation of calcium ion transport via store-operated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "down regulation of calcium ion transport via store-operated calcium channel" EXACT [] +synonym: "down-regulation of calcium ion transport via store-operated calcium channel" EXACT [] +synonym: "downregulation of calcium ion transport via store-operated calcium channel" EXACT [] +synonym: "inhibition of calcium ion transport via store-operated calcium channel" NARROW [] +synonym: "negative regulation of calcium ion transport via store-operated calcium channel activity" EXACT [] +synonym: "negative regulation of calcium transport via store-operated calcium channel" EXACT [] +synonym: "negative regulation of store-operated calcium channel activity" EXACT [] +is_obsolete: true +consider: GO:0015279 + +[Term] +id: GO:0032236 +name: obsolete positive regulation of calcium ion transport via store-operated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel." [GOC:bf, PMID:16582901] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "activation of calcium ion transport via store-operated calcium channel" NARROW [] +synonym: "positive regulation of calcium ion transport via store-operated calcium channel activity" EXACT [] +synonym: "positive regulation of calcium transport via store-operated calcium channel" EXACT [] +synonym: "positive regulation of store-operated calcium channel activity" EXACT [] +synonym: "stimulation of calcium ion transport via store-operated calcium channel" NARROW [] +synonym: "up regulation of calcium ion transport via store-operated calcium channel" EXACT [] +synonym: "up-regulation of calcium ion transport via store-operated calcium channel" EXACT [] +synonym: "upregulation of calcium ion transport via store-operated calcium channel" EXACT [] +is_obsolete: true +consider: GO:0015279 + +[Term] +id: GO:0032237 +name: activation of store-operated calcium channel activity +namespace: biological_process +def: "A process that initiates the activity of an inactive store-operated calcium channel." [GOC:mah] +is_a: GO:1901341 ! positive regulation of store-operated calcium channel activity + +[Term] +id: GO:0032238 +name: adenosine transport +namespace: biological_process +def: "The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0015858 ! nucleoside transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0032239 +name: regulation of nucleobase-containing compound transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015931 ! nucleobase-containing compound transport +relationship: regulates GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0032240 +name: negative regulation of nucleobase-containing compound transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] +synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015931 ! nucleobase-containing compound transport +relationship: negatively_regulates GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0032241 +name: positive regulation of nucleobase-containing compound transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] +synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] +synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] +synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015931 ! nucleobase-containing compound transport +relationship: positively_regulates GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0032242 +name: regulation of nucleoside transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015858 ! nucleoside transport +relationship: regulates GO:0015858 ! nucleoside transport + +[Term] +id: GO:0032243 +name: negative regulation of nucleoside transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of nucleoside transport" EXACT [] +synonym: "down-regulation of nucleoside transport" EXACT [] +synonym: "downregulation of nucleoside transport" EXACT [] +synonym: "inhibition of nucleoside transport" NARROW [] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0032242 ! regulation of nucleoside transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015858 ! nucleoside transport +relationship: negatively_regulates GO:0015858 ! nucleoside transport + +[Term] +id: GO:0032244 +name: positive regulation of nucleoside transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of nucleoside transport" NARROW [] +synonym: "stimulation of nucleoside transport" NARROW [] +synonym: "up regulation of nucleoside transport" EXACT [] +synonym: "up-regulation of nucleoside transport" EXACT [] +synonym: "upregulation of nucleoside transport" EXACT [] +is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport +is_a: GO:0032242 ! regulation of nucleoside transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015858 ! nucleoside transport +relationship: positively_regulates GO:0015858 ! nucleoside transport + +[Term] +id: GO:0032245 +name: regulation of purine nucleoside transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032242 ! regulation of nucleoside transport + +[Term] +id: GO:0032246 +name: regulation of pyrimidine nucleoside transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032242 ! regulation of nucleoside transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015864 ! pyrimidine nucleoside transport +relationship: regulates GO:0015864 ! pyrimidine nucleoside transport + +[Term] +id: GO:0032247 +name: negative regulation of purine nucleoside transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of purine nucleoside transport" EXACT [] +synonym: "down-regulation of purine nucleoside transport" EXACT [] +synonym: "downregulation of purine nucleoside transport" EXACT [] +synonym: "inhibition of purine nucleoside transport" NARROW [] +is_a: GO:0032243 ! negative regulation of nucleoside transport +is_a: GO:0032245 ! regulation of purine nucleoside transport + +[Term] +id: GO:0032248 +name: positive regulation of purine nucleoside transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of purine nucleoside transport" NARROW [] +synonym: "stimulation of purine nucleoside transport" NARROW [] +synonym: "up regulation of purine nucleoside transport" EXACT [] +synonym: "up-regulation of purine nucleoside transport" EXACT [] +synonym: "upregulation of purine nucleoside transport" EXACT [] +is_a: GO:0032244 ! positive regulation of nucleoside transport +is_a: GO:0032245 ! regulation of purine nucleoside transport + +[Term] +id: GO:0032249 +name: regulation of adenosine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032245 ! regulation of purine nucleoside transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032238 ! adenosine transport +relationship: regulates GO:0032238 ! adenosine transport + +[Term] +id: GO:0032250 +name: negative regulation of adenosine transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of adenosine transport" EXACT [] +synonym: "down-regulation of adenosine transport" EXACT [] +synonym: "downregulation of adenosine transport" EXACT [] +synonym: "inhibition of adenosine transport" NARROW [] +is_a: GO:0032247 ! negative regulation of purine nucleoside transport +is_a: GO:0032249 ! regulation of adenosine transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032238 ! adenosine transport +relationship: negatively_regulates GO:0032238 ! adenosine transport + +[Term] +id: GO:0032251 +name: positive regulation of adenosine transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of adenosine transport" NARROW [] +synonym: "stimulation of adenosine transport" NARROW [] +synonym: "up regulation of adenosine transport" EXACT [] +synonym: "up-regulation of adenosine transport" EXACT [] +synonym: "upregulation of adenosine transport" EXACT [] +is_a: GO:0032248 ! positive regulation of purine nucleoside transport +is_a: GO:0032249 ! regulation of adenosine transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032238 ! adenosine transport +relationship: positively_regulates GO:0032238 ! adenosine transport + +[Term] +id: GO:0032252 +name: secretory granule localization +namespace: biological_process +def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] +synonym: "secretory granule clustering" RELATED [] +synonym: "secretory granule localisation" EXACT [GOC:mah] +is_a: GO:0051648 ! vesicle localization + +[Term] +id: GO:0032253 +name: dense core granule localization +namespace: biological_process +def: "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] +synonym: "dense core granule clustering" RELATED [] +synonym: "dense core granule localisation" EXACT [GOC:mah] +synonym: "dense core vesicle localization" EXACT [GOC:kmv] +is_a: GO:0032252 ! secretory granule localization + +[Term] +id: GO:0032254 +name: establishment of secretory granule localization +namespace: biological_process +def: "The directed movement of a secretory granule to a specific location." [GOC:mah] +synonym: "establishment of secretory granule localisation" EXACT [GOC:mah] +is_a: GO:0051650 ! establishment of vesicle localization +relationship: part_of GO:0032252 ! secretory granule localization + +[Term] +id: GO:0032255 +name: maintenance of secretory granule location +namespace: biological_process +def: "Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of secretory granule localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051655 ! maintenance of vesicle location +relationship: part_of GO:0032252 ! secretory granule localization + +[Term] +id: GO:0032256 +name: establishment of dense core granule localization +namespace: biological_process +def: "The directed movement of a dense core granule to a specific location." [GOC:mah] +synonym: "establishment of dense core granule localisation" EXACT [GOC:mah] +synonym: "establishment of dense core vesicle localization" EXACT [GOC:kmv] +is_a: GO:0032254 ! establishment of secretory granule localization +relationship: part_of GO:0032253 ! dense core granule localization + +[Term] +id: GO:0032257 +name: maintenance of dense core granule location +namespace: biological_process +def: "Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of dense core granule localization" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of dense core vesicle location" EXACT [GOC:kmv] +is_a: GO:0032255 ! maintenance of secretory granule location +relationship: part_of GO:0032253 ! dense core granule localization + +[Term] +id: GO:0032258 +name: cytoplasm to vacuole transport by the Cvt pathway +namespace: biological_process +def: "A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast." [PMID:12865942, PMID:15659643] +synonym: "cytoplasm to vacuole targeting" BROAD [] +synonym: "cytoplasm-to-vacuole targeting" BROAD [] +synonym: "protein localization by the Cvt pathway" EXACT [] +is_a: GO:0006623 ! protein targeting to vacuole +is_a: GO:0061919 ! process utilizing autophagic mechanism +relationship: has_part GO:0006624 ! vacuolar protein processing + +[Term] +id: GO:0032259 +name: methylation +namespace: biological_process +def: "The process in which a methyl group is covalently attached to a molecule." [GOC:mah] +subset: goslim_chembl +xref: Wikipedia:Methylation +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0032260 +name: response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen." [GOC:mah] +synonym: "response to jasmonic acid stimulus during jasmonic acid and ethylene-dependent systemic resistance" RELATED [GOC:dph, GOC:tb] +is_a: GO:0009753 ! response to jasmonic acid +intersection_of: GO:0009753 ! response to jasmonic acid +intersection_of: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance +relationship: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance + +[Term] +id: GO:0032261 +name: purine nucleotide salvage +namespace: biological_process +def: "Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis." [GOC:jp] +is_a: GO:0006164 ! purine nucleotide biosynthetic process +is_a: GO:0043101 ! purine-containing compound salvage +is_a: GO:0043173 ! nucleotide salvage + +[Term] +id: GO:0032262 +name: pyrimidine nucleotide salvage +namespace: biological_process +def: "Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis." [GOC:mah] +is_a: GO:0006221 ! pyrimidine nucleotide biosynthetic process +is_a: GO:0008655 ! pyrimidine-containing compound salvage +is_a: GO:0043173 ! nucleotide salvage + +[Term] +id: GO:0032263 +name: GMP salvage +namespace: biological_process +def: "Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah] +is_a: GO:0006166 ! purine ribonucleoside salvage +is_a: GO:0006177 ! GMP biosynthetic process +is_a: GO:0032261 ! purine nucleotide salvage + +[Term] +id: GO:0032264 +name: IMP salvage +namespace: biological_process +def: "Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah] +is_a: GO:0006188 ! IMP biosynthetic process +is_a: GO:0032261 ! purine nucleotide salvage + +[Term] +id: GO:0032265 +name: XMP salvage +namespace: biological_process +def: "Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis." [GOC:mah] +is_a: GO:0032261 ! purine nucleotide salvage +is_a: GO:0097293 ! XMP biosynthetic process + +[Term] +id: GO:0032266 +name: phosphatidylinositol-3-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position." [GOC:bf, PMID:10209156, PMID:11395417, PMID:11557775] +synonym: "phosphatidylinositol 3-phosphate binding" EXACT [] +synonym: "PtdIns-3-P binding" EXACT [] +is_a: GO:1901981 ! phosphatidylinositol phosphate binding + +[Term] +id: GO:0032267 +name: tRNA(Ile)-lysidine synthase activity +namespace: molecular_function +def: "Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine." [PMID:14527414] +synonym: "tRNA(Ile)-2-lysyl-cytidine synthase activity" EXACT [] +synonym: "tRNA(Ile)-lysidine synthetase activity" EXACT [] +xref: EC:6.3.4 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0032268 +name: regulation of cellular protein metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] +synonym: "regulation of cellular protein metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044267 ! cellular protein metabolic process +relationship: regulates GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0032269 +name: negative regulation of cellular protein metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] +synonym: "down regulation of cellular protein metabolic process" EXACT [] +synonym: "down-regulation of cellular protein metabolic process" EXACT [] +synonym: "downregulation of cellular protein metabolic process" EXACT [] +synonym: "inhibition of cellular protein metabolic process" NARROW [] +synonym: "negative regulation of cellular protein metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044267 ! cellular protein metabolic process +relationship: negatively_regulates GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0032270 +name: positive regulation of cellular protein metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] +synonym: "activation of cellular protein metabolic process" NARROW [] +synonym: "positive regulation of cellular protein metabolism" EXACT [] +synonym: "stimulation of cellular protein metabolic process" NARROW [] +synonym: "up regulation of cellular protein metabolic process" EXACT [] +synonym: "up-regulation of cellular protein metabolic process" EXACT [] +synonym: "upregulation of cellular protein metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044267 ! cellular protein metabolic process +relationship: positively_regulates GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0032271 +name: regulation of protein polymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] +synonym: "regulation of protein polymerisation" EXACT [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051258 ! protein polymerization +relationship: regulates GO:0051258 ! protein polymerization + +[Term] +id: GO:0032272 +name: negative regulation of protein polymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] +synonym: "down regulation of protein polymerization" EXACT [] +synonym: "down-regulation of protein polymerization" EXACT [] +synonym: "downregulation of protein polymerization" EXACT [] +synonym: "inhibition of protein polymerization" NARROW [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0032271 ! regulation of protein polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051258 ! protein polymerization +relationship: negatively_regulates GO:0051258 ! protein polymerization + +[Term] +id: GO:0032273 +name: positive regulation of protein polymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] +synonym: "activation of protein polymerization" NARROW [] +synonym: "stimulation of protein polymerization" NARROW [] +synonym: "up regulation of protein polymerization" EXACT [] +synonym: "up-regulation of protein polymerization" EXACT [] +synonym: "upregulation of protein polymerization" EXACT [] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0032271 ! regulation of protein polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051258 ! protein polymerization +relationship: positively_regulates GO:0051258 ! protein polymerization + +[Term] +id: GO:0032274 +name: gonadotropin secretion +namespace: biological_process +def: "The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone." [GOC:mah, ISBN:0721662544] +synonym: "gonadotrophin secretion" EXACT [] +is_a: GO:0060986 ! endocrine hormone secretion + +[Term] +id: GO:0032275 +name: luteinizing hormone secretion +namespace: biological_process +def: "The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary." [ISBN:0198506732] +is_a: GO:0032274 ! gonadotropin secretion + +[Term] +id: GO:0032276 +name: regulation of gonadotropin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] +synonym: "regulation of gonadotrophin secretion" EXACT [] +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032274 ! gonadotropin secretion +relationship: regulates GO:0032274 ! gonadotropin secretion + +[Term] +id: GO:0032277 +name: negative regulation of gonadotropin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] +synonym: "down regulation of gonadotropin secretion" EXACT [] +synonym: "down-regulation of gonadotropin secretion" EXACT [] +synonym: "downregulation of gonadotropin secretion" EXACT [] +synonym: "inhibition of gonadotropin secretion" NARROW [] +synonym: "negative regulation of gonadotrophin secretion" EXACT [GOC:dph] +is_a: GO:0032276 ! regulation of gonadotropin secretion +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032274 ! gonadotropin secretion +relationship: negatively_regulates GO:0032274 ! gonadotropin secretion + +[Term] +id: GO:0032278 +name: positive regulation of gonadotropin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] +synonym: "activation of gonadotropin secretion" NARROW [] +synonym: "positive regulation of gonadotrophin secretion" EXACT [GOC:dph] +synonym: "stimulation of gonadotropin secretion" NARROW [] +synonym: "up regulation of gonadotropin secretion" EXACT [] +synonym: "up-regulation of gonadotropin secretion" EXACT [] +synonym: "upregulation of gonadotropin secretion" EXACT [] +is_a: GO:0032276 ! regulation of gonadotropin secretion +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032274 ! gonadotropin secretion +relationship: positively_regulates GO:0032274 ! gonadotropin secretion + +[Term] +id: GO:0032279 +name: asymmetric synapse +namespace: cellular_component +def: "A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory." [GOC:dgh, GOC:ef] +synonym: "Gray's type I synapse" EXACT [] +is_a: GO:0098984 ! neuron to neuron synapse +intersection_of: GO:0098984 ! neuron to neuron synapse +intersection_of: has_part GO:0014069 ! postsynaptic density +disjoint_from: GO:0032280 ! symmetric synapse +relationship: has_part GO:0014069 ! postsynaptic density + +[Term] +id: GO:0032280 +name: symmetric synapse +namespace: cellular_component +def: "A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory." [GOC:dgh, GOC:ef] +comment: The term 'symmetric' in this name refers only to gross morphology. There is no implication of functional symmetry. +synonym: "Gray's type II synapse" EXACT [] +is_a: GO:0098984 ! neuron to neuron synapse + +[Term] +id: GO:0032281 +name: AMPA glutamate receptor complex +namespace: cellular_component +def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus." [GOC:ef] +synonym: "alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex" EXACT [] +synonym: "AMPA receptor" RELATED [] +synonym: "AMPA-selective glutamate receptor complex" EXACT [] +is_a: GO:0008328 ! ionotropic glutamate receptor complex +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0032282 +name: plastid acetyl-CoA carboxylase complex +namespace: cellular_component +def: "An acetyl-CoA carboxylase complex located in the stroma of a plastid." [GOC:mah] +synonym: "plastid ACCase complex" EXACT [] +is_a: GO:0009317 ! acetyl-CoA carboxylase complex +relationship: part_of GO:0009532 ! plastid stroma + +[Term] +id: GO:0032283 +name: plastid acetate CoA-transferase complex +namespace: cellular_component +def: "An acetate CoA-transferase complex located in the stroma of a plastid." [GOC:mah] +is_a: GO:0009329 ! acetate CoA-transferase complex +relationship: part_of GO:0032282 ! plastid acetyl-CoA carboxylase complex + +[Term] +id: GO:0032284 +name: plastid biotin carboxylase complex +namespace: cellular_component +def: "A biotin carboxylase complex located in the stroma of a plastid." [GOC:mah] +is_a: GO:0009343 ! biotin carboxylase complex +intersection_of: GO:0009343 ! biotin carboxylase complex +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0032282 ! plastid acetyl-CoA carboxylase complex + +[Term] +id: GO:0032285 +name: non-myelinated axon ensheathment +namespace: biological_process +def: "The process in which a non-myelinating glial cell membrane closes around an axon." [GOC:dgh] +synonym: "ensheathment of non-myelinated axons" EXACT [] +is_a: GO:0008366 ! axon ensheathment + +[Term] +id: GO:0032286 +name: central nervous system myelin maintenance +namespace: biological_process +def: "The process in which the structure and material content of mature central nervous system myelin is kept in a functional state." [GOC:dgh] +synonym: "myelin maintenance in central nervous system" EXACT [] +is_a: GO:0043217 ! myelin maintenance +relationship: part_of GO:0022010 ! central nervous system myelination + +[Term] +id: GO:0032287 +name: peripheral nervous system myelin maintenance +namespace: biological_process +def: "The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state." [GOC:dgh] +synonym: "myelin maintenance in peripheral nervous system" EXACT [] +is_a: GO:0043217 ! myelin maintenance +relationship: part_of GO:0022011 ! myelination in peripheral nervous system + +[Term] +id: GO:0032288 +name: myelin assembly +namespace: biological_process +def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system." [GOC:dgh, GOC:dph, GOC:tb] +synonym: "myelin formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +relationship: part_of GO:0042552 ! myelination + +[Term] +id: GO:0032289 +name: central nervous system myelin formation +namespace: biological_process +def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system." [GOC:dgh] +synonym: "myelin formation in central nervous system" EXACT [] +is_a: GO:0032288 ! myelin assembly +relationship: part_of GO:0022010 ! central nervous system myelination + +[Term] +id: GO:0032290 +name: peripheral nervous system myelin formation +namespace: biological_process +def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system." [GOC:dgh] +synonym: "myelin formation in peripheral nervous system" EXACT [] +is_a: GO:0032288 ! myelin assembly +relationship: part_of GO:0022011 ! myelination in peripheral nervous system + +[Term] +id: GO:0032291 +name: axon ensheathment in central nervous system +namespace: biological_process +def: "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] +synonym: "ensheathment of axons in central nervous system" EXACT [] +is_a: GO:0008366 ! axon ensheathment + +[Term] +id: GO:0032292 +name: peripheral nervous system axon ensheathment +namespace: biological_process +def: "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] +synonym: "ensheathment of axons in peripheral nervous system" EXACT [] +is_a: GO:0008366 ! axon ensheathment + +[Term] +id: GO:0032293 +name: non-myelinated axon ensheathment in central nervous system +namespace: biological_process +def: "The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system." [GOC:dgh] +synonym: "ensheathment of non-myelinated axons in central nervous system" EXACT [] +is_a: GO:0032285 ! non-myelinated axon ensheathment +is_a: GO:0032291 ! axon ensheathment in central nervous system + +[Term] +id: GO:0032294 +name: peripheral nervous system non-myelinated axon ensheathment +namespace: biological_process +def: "The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons." [GOC:dgh] +synonym: "ensheathment of non-myelinated axons in peripheral nervous system" EXACT [] +is_a: GO:0032285 ! non-myelinated axon ensheathment +is_a: GO:0032292 ! peripheral nervous system axon ensheathment + +[Term] +id: GO:0032295 +name: ensheathment of neuronal cell bodies +namespace: biological_process +def: "The process in which satellite glial cells isolate neuronal cell bodies." [GOC:dgh] +is_a: GO:0007272 ! ensheathment of neurons + +[Term] +id: GO:0032296 +name: double-stranded RNA-specific ribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules." [GOC:mah] +synonym: "double-stranded RNA-specific RNase activity" EXACT [] +synonym: "dsRNA-specific ribonuclease activity" EXACT [] +synonym: "dsRNA-specific RNase activity" EXACT [] +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0032297 +name: negative regulation of DNA-dependent DNA replication initiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication." [GOC:mah] +synonym: "down regulation of DNA replication initiation" EXACT [] +synonym: "down-regulation of DNA replication initiation" EXACT [] +synonym: "downregulation of DNA replication initiation" EXACT [] +synonym: "inhibition of DNA replication initiation" NARROW [] +synonym: "negative regulation of DNA replication initiation" BROAD [GOC:vw] +is_a: GO:0030174 ! regulation of DNA-dependent DNA replication initiation +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006270 ! DNA replication initiation +relationship: negatively_regulates GO:0006270 ! DNA replication initiation + +[Term] +id: GO:0032298 +name: positive regulation of DNA-dependent DNA replication initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication." [GOC:mah] +synonym: "activation of DNA replication initiation" NARROW [] +synonym: "negative regulation of DNA replication initiation" BROAD [GOC:vw] +synonym: "stimulation of DNA replication initiation" NARROW [] +synonym: "up regulation of DNA replication initiation" EXACT [] +synonym: "up-regulation of DNA replication initiation" EXACT [] +synonym: "upregulation of DNA replication initiation" EXACT [] +is_a: GO:0030174 ! regulation of DNA-dependent DNA replication initiation +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006270 ! DNA replication initiation +relationship: positively_regulates GO:0006270 ! DNA replication initiation + +[Term] +id: GO:0032299 +name: ribonuclease H2 complex +namespace: cellular_component +def: "A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p." [GOC:mah, PMID:14734815] +synonym: "RNase H2 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032300 +name: mismatch repair complex +namespace: cellular_component +def: "Any complex formed of proteins that act in mismatch repair." [GOC:mah] +subset: goslim_pir +is_a: GO:1990391 ! DNA repair complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032301 +name: MutSalpha complex +namespace: cellular_component +def: "A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6." [PMID:11005803] +synonym: "MMR complex" BROAD [] +synonym: "MSH2/MSH6 complex" EXACT [] +is_a: GO:0032300 ! mismatch repair complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032302 +name: MutSbeta complex +namespace: cellular_component +def: "A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3." [PMID:11005803] +synonym: "MMR complex" BROAD [] +synonym: "MSH2/MSH3 complex" EXACT [] +is_a: GO:0032300 ! mismatch repair complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032303 +name: regulation of icosanoid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah] +synonym: "regulation of eicosanoid secretion" EXACT [] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:2000191 ! regulation of fatty acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032309 ! icosanoid secretion +relationship: regulates GO:0032309 ! icosanoid secretion + +[Term] +id: GO:0032304 +name: negative regulation of icosanoid secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah] +synonym: "down regulation of icosanoid secretion" EXACT [] +synonym: "down-regulation of icosanoid secretion" EXACT [] +synonym: "downregulation of icosanoid secretion" EXACT [] +synonym: "inhibition of icosanoid secretion" NARROW [] +synonym: "negative regulation of eicosanoid secretion" EXACT [] +is_a: GO:0032303 ! regulation of icosanoid secretion +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:2000192 ! negative regulation of fatty acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032309 ! icosanoid secretion +relationship: negatively_regulates GO:0032309 ! icosanoid secretion + +[Term] +id: GO:0032305 +name: positive regulation of icosanoid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell." [GOC:mah] +synonym: "activation of icosanoid secretion" NARROW [] +synonym: "positive regulation of eicosanoid secretion" EXACT [] +synonym: "stimulation of icosanoid secretion" NARROW [] +synonym: "up regulation of icosanoid secretion" EXACT [] +synonym: "up-regulation of icosanoid secretion" EXACT [] +synonym: "upregulation of icosanoid secretion" EXACT [] +is_a: GO:0032303 ! regulation of icosanoid secretion +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:2000193 ! positive regulation of fatty acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032309 ! icosanoid secretion +relationship: positively_regulates GO:0032309 ! icosanoid secretion + +[Term] +id: GO:0032306 +name: regulation of prostaglandin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah] +synonym: "regulation of prostacyclin secretion" NARROW [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0032303 ! regulation of icosanoid secretion +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032310 ! prostaglandin secretion +relationship: regulates GO:0032310 ! prostaglandin secretion + +[Term] +id: GO:0032307 +name: negative regulation of prostaglandin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah] +synonym: "down regulation of prostaglandin secretion" EXACT [] +synonym: "down-regulation of prostaglandin secretion" EXACT [] +synonym: "downregulation of prostaglandin secretion" EXACT [] +synonym: "inhibition of prostaglandin secretion" NARROW [] +synonym: "negative regulation of prostacyclin secretion" NARROW [] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0032304 ! negative regulation of icosanoid secretion +is_a: GO:0032306 ! regulation of prostaglandin secretion +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032310 ! prostaglandin secretion +relationship: negatively_regulates GO:0032310 ! prostaglandin secretion + +[Term] +id: GO:0032308 +name: positive regulation of prostaglandin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:mah] +synonym: "activation of prostaglandin secretion" NARROW [] +synonym: "positive regulation of prostacyclin secretion" NARROW [] +synonym: "stimulation of prostaglandin secretion" NARROW [] +synonym: "up regulation of prostaglandin secretion" EXACT [] +synonym: "up-regulation of prostaglandin secretion" EXACT [] +synonym: "upregulation of prostaglandin secretion" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0032305 ! positive regulation of icosanoid secretion +is_a: GO:0032306 ! regulation of prostaglandin secretion +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032310 ! prostaglandin secretion +relationship: positively_regulates GO:0032310 ! prostaglandin secretion + +[Term] +id: GO:0032309 +name: icosanoid secretion +namespace: biological_process +def: "The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue." [GOC:mah] +synonym: "eicosanoid secretion" EXACT [] +is_a: GO:0046717 ! acid secretion +is_a: GO:0071715 ! icosanoid transport + +[Term] +id: GO:0032310 +name: prostaglandin secretion +namespace: biological_process +def: "The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue." [GOC:mah] +synonym: "prostacyclin secretion" NARROW [] +is_a: GO:0015732 ! prostaglandin transport +is_a: GO:0023061 ! signal release +is_a: GO:0032309 ! icosanoid secretion +is_a: GO:0140353 ! lipid export from cell + +[Term] +id: GO:0032311 +name: angiogenin-PRI complex +namespace: cellular_component +def: "A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis." [PMID:2706246, PMID:3470787] +synonym: "angiogenin-placental ribonuclease inhibitor complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0032322 +name: ubiquinone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme." [GOC:mah] +synonym: "ubiquinone breakdown" EXACT [] +synonym: "ubiquinone catabolism" EXACT [] +synonym: "ubiquinone degradation" EXACT [] +is_a: GO:0006743 ! ubiquinone metabolic process +is_a: GO:1901662 ! quinone catabolic process + +[Term] +id: GO:0032323 +name: lipoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipoate." [GOC:mah] +synonym: "lipoic acid breakdown" EXACT [] +synonym: "lipoic acid catabolism" EXACT [] +synonym: "lipoic acid degradation" EXACT [] +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0009106 ! lipoate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0032324 +name: molybdopterin cofactor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [GOC:mah] +synonym: "molybdopterin cofactor anabolism" EXACT [] +synonym: "molybdopterin cofactor biosynthesis" RELATED [] +synonym: "molybdopterin cofactor formation" RELATED [] +synonym: "molybdopterin cofactor synthesis" EXACT [] +xref: MetaCyc:Molybdenum-Cofactor-Biosynthesis +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043545 ! molybdopterin cofactor metabolic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: has_part GO:0030366 ! molybdopterin synthase activity +relationship: has_part GO:0031071 ! cysteine desulfurase activity +relationship: has_part GO:0061598 ! molybdopterin adenylyltransferase activity +relationship: has_part GO:0061604 ! molybdopterin-synthase sulfurtransferase activity +relationship: has_part GO:0061605 ! molybdopterin-synthase adenylyltransferase activity + +[Term] +id: GO:0032325 +name: molybdopterin cofactor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [GOC:mah] +is_a: GO:0043545 ! molybdopterin cofactor metabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0032326 +name: Mo-molybdopterin cofactor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands." [GOC:mah] +synonym: "Mo-molybdopterin cofactor breakdown" EXACT [] +synonym: "Mo-molybdopterin cofactor catabolism" EXACT [] +synonym: "Mo-molybdopterin cofactor degradation" EXACT [] +synonym: "Moco catabolic process" BROAD [] +synonym: "Moco catabolism" BROAD [] +is_a: GO:0019720 ! Mo-molybdopterin cofactor metabolic process +is_a: GO:0032325 ! molybdopterin cofactor catabolic process + +[Term] +id: GO:0032327 +name: W-molybdopterin cofactor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands." [GOC:mah] +synonym: "Moco catabolic process" BROAD [] +synonym: "Moco catabolism" BROAD [] +synonym: "W-molybdopterin cofactor breakdown" EXACT [] +synonym: "W-molybdopterin cofactor catabolism" EXACT [] +synonym: "W-molybdopterin cofactor degradation" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0032325 ! molybdopterin cofactor catabolic process +is_a: GO:0042046 ! W-molybdopterin cofactor metabolic process + +[Term] +id: GO:0032328 +name: alanine transport +namespace: biological_process +def: "The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0032329 +name: serine transport +namespace: biological_process +alt_id: GO:0090478 +def: "The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "serine import" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport +created_by: tb +creation_date: 2012-10-01T11:10:51Z + +[Term] +id: GO:0032330 +name: regulation of chondrocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0061035 ! regulation of cartilage development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002062 ! chondrocyte differentiation +relationship: regulates GO:0002062 ! chondrocyte differentiation + +[Term] +id: GO:0032331 +name: negative regulation of chondrocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] +synonym: "down regulation of chondrocyte differentiation" EXACT [] +synonym: "down-regulation of chondrocyte differentiation" EXACT [] +synonym: "downregulation of chondrocyte differentiation" EXACT [] +synonym: "inhibition of chondrocyte differentiation" NARROW [] +is_a: GO:0032330 ! regulation of chondrocyte differentiation +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0061037 ! negative regulation of cartilage development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002062 ! chondrocyte differentiation +relationship: negatively_regulates GO:0002062 ! chondrocyte differentiation + +[Term] +id: GO:0032332 +name: positive regulation of chondrocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] +synonym: "activation of chondrocyte differentiation" NARROW [] +synonym: "stimulation of chondrocyte differentiation" NARROW [] +synonym: "up regulation of chondrocyte differentiation" EXACT [] +synonym: "up-regulation of chondrocyte differentiation" EXACT [] +synonym: "upregulation of chondrocyte differentiation" EXACT [] +is_a: GO:0032330 ! regulation of chondrocyte differentiation +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0061036 ! positive regulation of cartilage development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002062 ! chondrocyte differentiation +relationship: positively_regulates GO:0002062 ! chondrocyte differentiation + +[Term] +id: GO:0032333 +name: activin secretion +namespace: biological_process +def: "The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone." [GOC:mah] +is_a: GO:0046879 ! hormone secretion + +[Term] +id: GO:0032334 +name: inhibin secretion +namespace: biological_process +def: "The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone." [GOC:mah] +is_a: GO:0060986 ! endocrine hormone secretion + +[Term] +id: GO:0032335 +name: regulation of activin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah] +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032333 ! activin secretion +relationship: regulates GO:0032333 ! activin secretion + +[Term] +id: GO:0032336 +name: negative regulation of activin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah] +synonym: "down regulation of activin secretion" EXACT [] +synonym: "down-regulation of activin secretion" EXACT [] +synonym: "downregulation of activin secretion" EXACT [] +synonym: "inhibition of activin secretion" NARROW [] +is_a: GO:0032335 ! regulation of activin secretion +is_a: GO:0046888 ! negative regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032333 ! activin secretion +relationship: negatively_regulates GO:0032333 ! activin secretion + +[Term] +id: GO:0032337 +name: positive regulation of activin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell." [GOC:mah] +synonym: "activation of activin secretion" NARROW [] +synonym: "stimulation of activin secretion" NARROW [] +synonym: "up regulation of activin secretion" EXACT [] +synonym: "up-regulation of activin secretion" EXACT [] +synonym: "upregulation of activin secretion" EXACT [] +is_a: GO:0032335 ! regulation of activin secretion +is_a: GO:0046887 ! positive regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032333 ! activin secretion +relationship: positively_regulates GO:0032333 ! activin secretion + +[Term] +id: GO:0032338 +name: regulation of inhibin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah] +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032334 ! inhibin secretion +relationship: regulates GO:0032334 ! inhibin secretion + +[Term] +id: GO:0032339 +name: negative regulation of inhibin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah] +synonym: "down regulation of inhibin secretion" EXACT [] +synonym: "down-regulation of inhibin secretion" EXACT [] +synonym: "downregulation of inhibin secretion" EXACT [] +synonym: "inhibition of inhibin secretion" NARROW [] +is_a: GO:0032338 ! regulation of inhibin secretion +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032334 ! inhibin secretion +relationship: negatively_regulates GO:0032334 ! inhibin secretion + +[Term] +id: GO:0032340 +name: positive regulation of inhibin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell." [GOC:mah] +synonym: "activation of inhibin secretion" NARROW [] +synonym: "stimulation of inhibin secretion" NARROW [] +synonym: "up regulation of inhibin secretion" EXACT [] +synonym: "up-regulation of inhibin secretion" EXACT [] +synonym: "upregulation of inhibin secretion" EXACT [] +is_a: GO:0032338 ! regulation of inhibin secretion +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032334 ! inhibin secretion +relationship: positively_regulates GO:0032334 ! inhibin secretion + +[Term] +id: GO:0032341 +name: aldosterone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843] +synonym: "aldosterone metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0008207 ! C21-steroid hormone metabolic process +is_a: GO:0008212 ! mineralocorticoid metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0032342 +name: aldosterone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843] +is_a: GO:0006700 ! C21-steroid hormone biosynthetic process +is_a: GO:0006705 ! mineralocorticoid biosynthetic process +is_a: GO:0032341 ! aldosterone metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process + +[Term] +id: GO:0032343 +name: aldosterone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance." [PMID:16527843] +is_a: GO:0006712 ! mineralocorticoid catabolic process +is_a: GO:0008208 ! C21-steroid hormone catabolic process +is_a: GO:0032341 ! aldosterone metabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046185 ! aldehyde catabolic process + +[Term] +id: GO:0032344 +name: regulation of aldosterone metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] +synonym: "regulation of aldosterone metabolism" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032341 ! aldosterone metabolic process +relationship: regulates GO:0032341 ! aldosterone metabolic process + +[Term] +id: GO:0032345 +name: negative regulation of aldosterone metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] +synonym: "down regulation of aldosterone metabolic process" EXACT [] +synonym: "down-regulation of aldosterone metabolic process" EXACT [] +synonym: "downregulation of aldosterone metabolic process" EXACT [] +synonym: "inhibition of aldosterone metabolic process" NARROW [] +synonym: "negative regulation of aldosterone metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0032344 ! regulation of aldosterone metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045939 ! negative regulation of steroid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032341 ! aldosterone metabolic process +relationship: negatively_regulates GO:0032341 ! aldosterone metabolic process + +[Term] +id: GO:0032346 +name: positive regulation of aldosterone metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] +synonym: "activation of aldosterone metabolic process" NARROW [] +synonym: "positive regulation of aldosterone metabolism" EXACT [] +synonym: "stimulation of aldosterone metabolic process" NARROW [] +synonym: "up regulation of aldosterone metabolic process" EXACT [] +synonym: "up-regulation of aldosterone metabolic process" EXACT [] +synonym: "upregulation of aldosterone metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0032344 ! regulation of aldosterone metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045940 ! positive regulation of steroid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032341 ! aldosterone metabolic process +relationship: positively_regulates GO:0032341 ! aldosterone metabolic process + +[Term] +id: GO:0032347 +name: regulation of aldosterone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0032344 ! regulation of aldosterone metabolic process +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032342 ! aldosterone biosynthetic process +relationship: regulates GO:0032342 ! aldosterone biosynthetic process + +[Term] +id: GO:0032348 +name: negative regulation of aldosterone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] +synonym: "down regulation of aldosterone biosynthetic process" EXACT [] +synonym: "down-regulation of aldosterone biosynthetic process" EXACT [] +synonym: "downregulation of aldosterone biosynthetic process" EXACT [] +synonym: "inhibition of aldosterone biosynthetic process" NARROW [] +is_a: GO:0032345 ! negative regulation of aldosterone metabolic process +is_a: GO:0032347 ! regulation of aldosterone biosynthetic process +is_a: GO:0090032 ! negative regulation of steroid hormone biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032342 ! aldosterone biosynthetic process +relationship: negatively_regulates GO:0032342 ! aldosterone biosynthetic process + +[Term] +id: GO:0032349 +name: positive regulation of aldosterone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] +synonym: "activation of aldosterone biosynthetic process" NARROW [] +synonym: "stimulation of aldosterone biosynthetic process" NARROW [] +synonym: "up regulation of aldosterone biosynthetic process" EXACT [] +synonym: "up-regulation of aldosterone biosynthetic process" EXACT [] +synonym: "upregulation of aldosterone biosynthetic process" EXACT [] +is_a: GO:0032346 ! positive regulation of aldosterone metabolic process +is_a: GO:0032347 ! regulation of aldosterone biosynthetic process +is_a: GO:0090031 ! positive regulation of steroid hormone biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032342 ! aldosterone biosynthetic process +relationship: positively_regulates GO:0032342 ! aldosterone biosynthetic process + +[Term] +id: GO:0032350 +name: regulation of hormone metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] +synonym: "regulation of hormone metabolism" EXACT [] +is_a: GO:0010817 ! regulation of hormone levels +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042445 ! hormone metabolic process +relationship: regulates GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0032351 +name: negative regulation of hormone metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] +synonym: "down regulation of hormone metabolic process" EXACT [] +synonym: "down-regulation of hormone metabolic process" EXACT [] +synonym: "downregulation of hormone metabolic process" EXACT [] +synonym: "inhibition of hormone metabolic process" NARROW [] +synonym: "negative regulation of hormone metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042445 ! hormone metabolic process +relationship: negatively_regulates GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0032352 +name: positive regulation of hormone metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] +synonym: "activation of hormone metabolic process" NARROW [] +synonym: "positive regulation of hormone metabolism" EXACT [] +synonym: "stimulation of hormone metabolic process" NARROW [] +synonym: "up regulation of hormone metabolic process" EXACT [] +synonym: "up-regulation of hormone metabolic process" EXACT [] +synonym: "upregulation of hormone metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042445 ! hormone metabolic process +relationship: positively_regulates GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0032353 +name: negative regulation of hormone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] +synonym: "down regulation of hormone biosynthetic process" EXACT [] +synonym: "down-regulation of hormone biosynthetic process" EXACT [] +synonym: "downregulation of hormone biosynthetic process" EXACT [] +synonym: "inhibition of hormone biosynthetic process" NARROW [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042446 ! hormone biosynthetic process +relationship: negatively_regulates GO:0042446 ! hormone biosynthetic process + +[Term] +id: GO:0032354 +name: response to follicle-stimulating hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus." [GOC:mah] +synonym: "response to follicle stimulating hormone stimulus" EXACT [] +synonym: "response to follicle-stimulating hormone stimulus" EXACT [GOC:dos] +synonym: "response to FSH stimulus" EXACT [] +is_a: GO:0034698 ! response to gonadotropin + +[Term] +id: GO:0032355 +name: response to estradiol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." [GOC:mah, ISBN:0911910123] +synonym: "response to E2 stimulus" EXACT [] +synonym: "response to estradiol stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0032356 +name: oxidized DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oxidized residues in DNA." [GOC:vk] +synonym: "oxidised DNA binding" EXACT [] +is_a: GO:0003684 ! damaged DNA binding + +[Term] +id: GO:0032357 +name: oxidized purine DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oxidized purine residues in DNA." [GOC:vk] +synonym: "oxidised purine DNA binding" EXACT [] +synonym: "oxidized purine base DNA binding" EXACT [] +synonym: "oxidized purine nucleobase DNA binding" EXACT [] +is_a: GO:0032356 ! oxidized DNA binding + +[Term] +id: GO:0032358 +name: oxidized pyrimidine DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oxidized pyrimidine residues in DNA." [GOC:vk] +synonym: "oxidised pyrimidine DNA binding" EXACT [] +synonym: "oxidized pyrimidine base DNA binding" EXACT [] +synonym: "oxidized pyrimidine nucleobase DNA binding" EXACT [] +is_a: GO:0032356 ! oxidized DNA binding + +[Term] +id: GO:0032359 +name: provirus excision +namespace: biological_process +def: "The molecular events that lead to the excision of a viral genome from the host genome." [GOC:mlg] +synonym: "prophage excision" EXACT [] +is_a: GO:0019046 ! release from viral latency + +[Term] +id: GO:0032361 +name: pyridoxal phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6." [GOC:mah] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042820 ! vitamin B6 catabolic process +is_a: GO:0042822 ! pyridoxal phosphate metabolic process +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0032362 +name: obsolete FAD catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide." [GOC:mah] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "FAD breakdown" EXACT [GOC:mah] +synonym: "FAD catabolism" EXACT [GOC:mah] +synonym: "FAD degradation" EXACT [GOC:mah] +synonym: "oxidized flavin adenine dinucleotide catabolic process" EXACT [GOC:mah] +is_obsolete: true + +[Term] +id: GO:0032363 +name: FMN catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase." [GOC:mah] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009158 ! ribonucleoside monophosphate catabolic process +is_a: GO:0009261 ! ribonucleotide catabolic process +is_a: GO:0042728 ! flavin-containing compound catabolic process +is_a: GO:0046444 ! FMN metabolic process + +[Term] +id: GO:0032364 +name: oxygen homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell." [GOC:rph] +is_a: GO:0033483 ! gas homeostasis + +[Term] +id: GO:0032365 +name: intracellular lipid transport +namespace: biological_process +def: "The directed movement of lipids within cells." [GOC:mah] +is_a: GO:0006869 ! lipid transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0032366 +name: intracellular sterol transport +namespace: biological_process +def: "The directed movement of sterols within cells." [GOC:mah] +is_a: GO:0015918 ! sterol transport +is_a: GO:0032365 ! intracellular lipid transport +intersection_of: GO:0015918 ! sterol transport +intersection_of: occurs_in GO:0005622 ! intracellular + +[Term] +id: GO:0032367 +name: intracellular cholesterol transport +namespace: biological_process +def: "The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells." [GOC:mah] +is_a: GO:0030301 ! cholesterol transport +is_a: GO:0032366 ! intracellular sterol transport +intersection_of: GO:0030301 ! cholesterol transport +intersection_of: occurs_in GO:0005622 ! intracellular + +[Term] +id: GO:0032368 +name: regulation of lipid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0051049 ! regulation of transport +is_a: GO:1905952 ! regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006869 ! lipid transport +relationship: regulates GO:0006869 ! lipid transport + +[Term] +id: GO:0032369 +name: negative regulation of lipid transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of lipid transport" EXACT [] +synonym: "down-regulation of lipid transport" EXACT [] +synonym: "downregulation of lipid transport" EXACT [] +synonym: "inhibition of lipid transport" NARROW [] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1905953 ! negative regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006869 ! lipid transport +relationship: negatively_regulates GO:0006869 ! lipid transport + +[Term] +id: GO:0032370 +name: positive regulation of lipid transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of lipid transport" NARROW [] +synonym: "stimulation of lipid transport" NARROW [] +synonym: "up regulation of lipid transport" EXACT [] +synonym: "up-regulation of lipid transport" EXACT [] +synonym: "upregulation of lipid transport" EXACT [] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1905954 ! positive regulation of lipid localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006869 ! lipid transport +relationship: positively_regulates GO:0006869 ! lipid transport + +[Term] +id: GO:0032371 +name: regulation of sterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032368 ! regulation of lipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015918 ! sterol transport +relationship: regulates GO:0015918 ! sterol transport + +[Term] +id: GO:0032372 +name: negative regulation of sterol transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of sterol transport" EXACT [] +synonym: "down-regulation of sterol transport" EXACT [] +synonym: "downregulation of sterol transport" EXACT [] +synonym: "inhibition of sterol transport" NARROW [] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0032371 ! regulation of sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015918 ! sterol transport +relationship: negatively_regulates GO:0015918 ! sterol transport + +[Term] +id: GO:0032373 +name: positive regulation of sterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of sterol transport" NARROW [] +synonym: "stimulation of sterol transport" NARROW [] +synonym: "up regulation of sterol transport" EXACT [] +synonym: "up-regulation of sterol transport" EXACT [] +synonym: "upregulation of sterol transport" EXACT [] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0032371 ! regulation of sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015918 ! sterol transport +relationship: positively_regulates GO:0015918 ! sterol transport + +[Term] +id: GO:0032374 +name: regulation of cholesterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0032371 ! regulation of sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030301 ! cholesterol transport +relationship: regulates GO:0030301 ! cholesterol transport + +[Term] +id: GO:0032375 +name: negative regulation of cholesterol transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of cholesterol transport" EXACT [] +synonym: "down-regulation of cholesterol transport" EXACT [] +synonym: "downregulation of cholesterol transport" EXACT [] +synonym: "inhibition of cholesterol transport" NARROW [] +is_a: GO:0032372 ! negative regulation of sterol transport +is_a: GO:0032374 ! regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030301 ! cholesterol transport +relationship: negatively_regulates GO:0030301 ! cholesterol transport + +[Term] +id: GO:0032376 +name: positive regulation of cholesterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of cholesterol transport" NARROW [] +synonym: "stimulation of cholesterol transport" NARROW [] +synonym: "up regulation of cholesterol transport" EXACT [] +synonym: "up-regulation of cholesterol transport" EXACT [] +synonym: "upregulation of cholesterol transport" EXACT [] +is_a: GO:0032373 ! positive regulation of sterol transport +is_a: GO:0032374 ! regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030301 ! cholesterol transport +relationship: positively_regulates GO:0030301 ! cholesterol transport + +[Term] +id: GO:0032377 +name: regulation of intracellular lipid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0032386 ! regulation of intracellular transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032365 ! intracellular lipid transport +relationship: regulates GO:0032365 ! intracellular lipid transport + +[Term] +id: GO:0032378 +name: negative regulation of intracellular lipid transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] +synonym: "down regulation of intracellular lipid transport" EXACT [] +synonym: "down-regulation of intracellular lipid transport" EXACT [] +synonym: "downregulation of intracellular lipid transport" EXACT [] +synonym: "inhibition of intracellular lipid transport" NARROW [] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0032377 ! regulation of intracellular lipid transport +is_a: GO:0032387 ! negative regulation of intracellular transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032365 ! intracellular lipid transport +relationship: negatively_regulates GO:0032365 ! intracellular lipid transport + +[Term] +id: GO:0032379 +name: positive regulation of intracellular lipid transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] +synonym: "activation of intracellular lipid transport" NARROW [] +synonym: "stimulation of intracellular lipid transport" NARROW [] +synonym: "up regulation of intracellular lipid transport" EXACT [] +synonym: "up-regulation of intracellular lipid transport" EXACT [] +synonym: "upregulation of intracellular lipid transport" EXACT [] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0032377 ! regulation of intracellular lipid transport +is_a: GO:0032388 ! positive regulation of intracellular transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032365 ! intracellular lipid transport +relationship: positively_regulates GO:0032365 ! intracellular lipid transport + +[Term] +id: GO:0032380 +name: regulation of intracellular sterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah] +is_a: GO:0032371 ! regulation of sterol transport +is_a: GO:0032377 ! regulation of intracellular lipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032366 ! intracellular sterol transport +relationship: regulates GO:0032366 ! intracellular sterol transport + +[Term] +id: GO:0032381 +name: negative regulation of intracellular sterol transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah] +synonym: "down regulation of intracellular sterol transport" EXACT [] +synonym: "down-regulation of intracellular sterol transport" EXACT [] +synonym: "downregulation of intracellular sterol transport" EXACT [] +synonym: "inhibition of intracellular sterol transport" NARROW [] +is_a: GO:0032372 ! negative regulation of sterol transport +is_a: GO:0032378 ! negative regulation of intracellular lipid transport +is_a: GO:0032380 ! regulation of intracellular sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032366 ! intracellular sterol transport +relationship: negatively_regulates GO:0032366 ! intracellular sterol transport + +[Term] +id: GO:0032382 +name: positive regulation of intracellular sterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells." [GOC:mah] +synonym: "activation of intracellular sterol transport" NARROW [] +synonym: "stimulation of intracellular sterol transport" NARROW [] +synonym: "up regulation of intracellular sterol transport" EXACT [] +synonym: "up-regulation of intracellular sterol transport" EXACT [] +synonym: "upregulation of intracellular sterol transport" EXACT [] +is_a: GO:0032373 ! positive regulation of sterol transport +is_a: GO:0032379 ! positive regulation of intracellular lipid transport +is_a: GO:0032380 ! regulation of intracellular sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032366 ! intracellular sterol transport +relationship: positively_regulates GO:0032366 ! intracellular sterol transport + +[Term] +id: GO:0032383 +name: regulation of intracellular cholesterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah] +is_a: GO:0032374 ! regulation of cholesterol transport +is_a: GO:0032380 ! regulation of intracellular sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032367 ! intracellular cholesterol transport +relationship: regulates GO:0032367 ! intracellular cholesterol transport + +[Term] +id: GO:0032384 +name: negative regulation of intracellular cholesterol transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah] +synonym: "down regulation of intracellular cholesterol transport" EXACT [] +synonym: "down-regulation of intracellular cholesterol transport" EXACT [] +synonym: "downregulation of intracellular cholesterol transport" EXACT [] +synonym: "inhibition of intracellular cholesterol transport" NARROW [] +is_a: GO:0032375 ! negative regulation of cholesterol transport +is_a: GO:0032381 ! negative regulation of intracellular sterol transport +is_a: GO:0032383 ! regulation of intracellular cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032367 ! intracellular cholesterol transport +relationship: negatively_regulates GO:0032367 ! intracellular cholesterol transport + +[Term] +id: GO:0032385 +name: positive regulation of intracellular cholesterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells." [GOC:mah] +synonym: "activation of intracellular cholesterol transport" NARROW [] +synonym: "stimulation of intracellular cholesterol transport" NARROW [] +synonym: "up regulation of intracellular cholesterol transport" EXACT [] +synonym: "up-regulation of intracellular cholesterol transport" EXACT [] +synonym: "upregulation of intracellular cholesterol transport" EXACT [] +is_a: GO:0032376 ! positive regulation of cholesterol transport +is_a: GO:0032382 ! positive regulation of intracellular sterol transport +is_a: GO:0032383 ! regulation of intracellular cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032367 ! intracellular cholesterol transport +relationship: positively_regulates GO:0032367 ! intracellular cholesterol transport + +[Term] +id: GO:0032386 +name: regulation of intracellular transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] +is_a: GO:0051049 ! regulation of transport +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046907 ! intracellular transport +relationship: regulates GO:0046907 ! intracellular transport + +[Term] +id: GO:0032387 +name: negative regulation of intracellular transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] +synonym: "down regulation of intracellular transport" EXACT [] +synonym: "down-regulation of intracellular transport" EXACT [] +synonym: "downregulation of intracellular transport" EXACT [] +synonym: "inhibition of intracellular transport" NARROW [] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046907 ! intracellular transport +relationship: negatively_regulates GO:0046907 ! intracellular transport + +[Term] +id: GO:0032388 +name: positive regulation of intracellular transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] +synonym: "activation of intracellular transport" NARROW [] +synonym: "stimulation of intracellular transport" NARROW [] +synonym: "up regulation of intracellular transport" EXACT [] +synonym: "up-regulation of intracellular transport" EXACT [] +synonym: "upregulation of intracellular transport" EXACT [] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046907 ! intracellular transport +relationship: positively_regulates GO:0046907 ! intracellular transport + +[Term] +id: GO:0032389 +name: MutLalpha complex +namespace: cellular_component +def: "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2." [GOC:vk] +synonym: "MLH1/PMS2 complex" EXACT [] +synonym: "MMR complex" BROAD [] +synonym: "MutL-alpha complex" EXACT [CORUM:292] +is_a: GO:0032300 ! mismatch repair complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032390 +name: MutLbeta complex +namespace: cellular_component +def: "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1." [GOC:vk] +synonym: "MLH1/PMS1 complex" EXACT [] +synonym: "MMR complex" BROAD [] +is_a: GO:0032300 ! mismatch repair complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032391 +name: photoreceptor connecting cilium +namespace: cellular_component +def: "The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone." [GOC:cilia, PMID:15917207, PMID:22653444, PMID:8718680] +synonym: "photoreceptor cilium" RELATED [] +is_a: GO:0035869 ! ciliary transition zone +relationship: part_of GO:0097733 ! photoreceptor cell cilium + +[Term] +id: GO:0032392 +name: DNA geometric change +namespace: biological_process +def: "The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases." [GOC:mah] +comment: Note that DNA geometric change and DNA topological change (GO:0006265) are distinct, but are usually coupled in vivo. +subset: goslim_pir +is_a: GO:0071103 ! DNA conformation change + +[Term] +id: GO:0032393 +name: MHC class I receptor activity +namespace: molecular_function +def: "Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149] +comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class I protein complexes, not for components of the MHC class I protein complexes themselves. +synonym: "alpha-beta T cell receptor activity" RELATED [] +synonym: "gamma-delta T cell receptor activity" RELATED [] +synonym: "T cell receptor activity" RELATED [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0042288 ! MHC class I protein binding + +[Term] +id: GO:0032394 +name: MHC class Ib receptor activity +namespace: molecular_function +def: "Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, GOC:signaling, ISBN:0781735149] +comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class Ib protein complexes, not for components of the MHC class Ib protein complexes themselves. +synonym: "alpha-beta T cell receptor activity" RELATED [] +synonym: "gamma-delta T cell receptor activity" RELATED [] +synonym: "T cell receptor activity" RELATED [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0023029 ! MHC class Ib protein binding + +[Term] +id: GO:0032395 +name: MHC class II receptor activity +namespace: molecular_function +def: "Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, ISBN:0781735149] +comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class II protein complexes, not for components of the MHC class II protein complexes themselves. +synonym: "alpha-beta T cell receptor activity" RELATED [] +synonym: "gamma-delta T cell receptor activity" RELATED [] +synonym: "T cell receptor activity" RELATED [] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0140375 ! immune receptor activity +relationship: has_part GO:0042289 ! MHC class II protein binding + +[Term] +id: GO:0032396 +name: inhibitory MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, PMID:11858820, PMID:9368779, PMID:9597134] +is_a: GO:0032393 ! MHC class I receptor activity + +[Term] +id: GO:0032397 +name: activating MHC class I receptor activity +namespace: molecular_function +def: "Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte." [GOC:add, PMID:11858820, PMID:9597134] +is_a: GO:0032393 ! MHC class I receptor activity + +[Term] +id: GO:0032398 +name: MHC class Ib protein complex +namespace: cellular_component +def: "A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, ISBN:0781735149, PMID:15928678] +is_a: GO:0042611 ! MHC protein complex + +[Term] +id: GO:0032399 +name: HECT domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein." [GOC:mah, Pfam:PF00632] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0032400 +name: melanosome localization +namespace: biological_process +def: "Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell." [GOC:ln] +synonym: "melanosome localisation" EXACT [GOC:mah] +is_a: GO:0051875 ! pigment granule localization + +[Term] +id: GO:0032401 +name: establishment of melanosome localization +namespace: biological_process +def: "The directed movement of a melanosome to a specific location." [GOC:mah] +synonym: "establishment of melanosome localisation" EXACT [GOC:mah] +is_a: GO:0051905 ! establishment of pigment granule localization +relationship: part_of GO:0032400 ! melanosome localization + +[Term] +id: GO:0032402 +name: melanosome transport +namespace: biological_process +def: "The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ln] +is_a: GO:0032400 ! melanosome localization +is_a: GO:0032401 ! establishment of melanosome localization +is_a: GO:0051904 ! pigment granule transport + +[Term] +id: GO:0032404 +name: mismatch repair complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mismatch repair complex." [GOC:vk] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0032405 +name: MutLalpha complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the mismatch repair complex MutLalpha." [GOC:vk] +is_a: GO:0032404 ! mismatch repair complex binding + +[Term] +id: GO:0032406 +name: MutLbeta complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the mismatch repair complex MutLbeta." [GOC:vk] +is_a: GO:0032404 ! mismatch repair complex binding + +[Term] +id: GO:0032407 +name: MutSalpha complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the mismatch repair complex MutSalpha." [GOC:vk] +is_a: GO:0032404 ! mismatch repair complex binding + +[Term] +id: GO:0032408 +name: MutSbeta complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the mismatch repair complex MutSbeta." [GOC:vk] +is_a: GO:0032404 ! mismatch repair complex binding + +[Term] +id: GO:0032409 +name: regulation of transporter activity +namespace: biological_process +def: "Any process that modulates the activity of a transporter." [GOC:mah] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005215 ! transporter activity +relationship: regulates GO:0005215 ! transporter activity + +[Term] +id: GO:0032410 +name: negative regulation of transporter activity +namespace: biological_process +def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] +synonym: "down regulation of transporter activity" EXACT [] +synonym: "down-regulation of transporter activity" EXACT [] +synonym: "downregulation of transporter activity" EXACT [] +synonym: "inhibition of transporter activity" NARROW [] +is_a: GO:0032409 ! regulation of transporter activity +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005215 ! transporter activity +relationship: negatively_regulates GO:0005215 ! transporter activity + +[Term] +id: GO:0032411 +name: positive regulation of transporter activity +namespace: biological_process +def: "Any process that activates or increases the activity of a transporter." [GOC:mah] +synonym: "activation of transporter activity" NARROW [] +synonym: "stimulation of transporter activity" NARROW [] +synonym: "up regulation of transporter activity" EXACT [] +synonym: "up-regulation of transporter activity" EXACT [] +synonym: "upregulation of transporter activity" EXACT [] +is_a: GO:0032409 ! regulation of transporter activity +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005215 ! transporter activity +relationship: positively_regulates GO:0005215 ! transporter activity + +[Term] +id: GO:0032412 +name: regulation of ion transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb] +synonym: "regulation of ion transporter activity" EXACT [GOC:tb] +is_a: GO:0022898 ! regulation of transmembrane transporter activity +is_a: GO:0034765 ! regulation of ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015075 ! ion transmembrane transporter activity +relationship: regulates GO:0015075 ! ion transmembrane transporter activity + +[Term] +id: GO:0032413 +name: negative regulation of ion transmembrane transporter activity +namespace: biological_process +def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] +synonym: "down regulation of ion transporter activity" EXACT [] +synonym: "down-regulation of ion transporter activity" EXACT [] +synonym: "downregulation of ion transporter activity" EXACT [] +synonym: "inhibition of ion transporter activity" NARROW [] +synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] +is_a: GO:0032410 ! negative regulation of transporter activity +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:0034766 ! negative regulation of ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015075 ! ion transmembrane transporter activity +relationship: negatively_regulates GO:0015075 ! ion transmembrane transporter activity + +[Term] +id: GO:0032414 +name: positive regulation of ion transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] +synonym: "activation of ion transporter activity" NARROW [] +synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] +synonym: "stimulation of ion transporter activity" NARROW [] +synonym: "up regulation of ion transporter activity" EXACT [] +synonym: "up-regulation of ion transporter activity" EXACT [] +synonym: "upregulation of ion transporter activity" EXACT [] +is_a: GO:0032411 ! positive regulation of transporter activity +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:0034767 ! positive regulation of ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015075 ! ion transmembrane transporter activity +relationship: positively_regulates GO:0015075 ! ion transmembrane transporter activity + +[Term] +id: GO:0032415 +name: regulation of sodium:proton antiporter activity +namespace: biological_process +def: "Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah, GOC:mtg_transport] +synonym: "regulation of sodium:hydrogen antiporter activity" EXACT [] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015385 ! sodium:proton antiporter activity +relationship: regulates GO:0015385 ! sodium:proton antiporter activity + +[Term] +id: GO:0032416 +name: negative regulation of sodium:proton antiporter activity +namespace: biological_process +def: "Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah] +synonym: "down regulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "down-regulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "downregulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "inhibition of sodium:hydrogen antiporter activity" NARROW [] +synonym: "negative regulation of sodium:hydrogen antiporter activity" EXACT [] +is_a: GO:0032415 ! regulation of sodium:proton antiporter activity +is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015385 ! sodium:proton antiporter activity +relationship: negatively_regulates GO:0015385 ! sodium:proton antiporter activity + +[Term] +id: GO:0032417 +name: positive regulation of sodium:proton antiporter activity +namespace: biological_process +def: "Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah] +synonym: "activation of sodium:hydrogen antiporter activity" NARROW [] +synonym: "positive regulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "stimulation of sodium:hydrogen antiporter activity" NARROW [] +synonym: "up regulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "up-regulation of sodium:hydrogen antiporter activity" EXACT [] +synonym: "upregulation of sodium:hydrogen antiporter activity" EXACT [] +is_a: GO:0032415 ! regulation of sodium:proton antiporter activity +is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015385 ! sodium:proton antiporter activity +relationship: positively_regulates GO:0015385 ! sodium:proton antiporter activity + +[Term] +id: GO:0032418 +name: lysosome localization +namespace: biological_process +def: "Any process in which a lysosome is transported to, and/or maintained in, a specific location." [GOC:mah] +synonym: "lysosome localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0032419 +name: extrinsic component of lysosome membrane +namespace: cellular_component +def: "The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:mah] +synonym: "extrinsic to lysosomal membrane" EXACT [] +synonym: "extrinsic to lysosome membrane" EXACT [] +is_a: GO:0000306 ! extrinsic component of vacuolar membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005765 ! lysosomal membrane +relationship: part_of GO:0005765 ! lysosomal membrane + +[Term] +id: GO:0032420 +name: stereocilium +namespace: cellular_component +def: "An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles." [GOC:ecd, PMID:15661519, PMID:7840137] +is_a: GO:0043005 ! neuron projection +is_a: GO:0098858 ! actin-based cell projection +relationship: part_of GO:0032421 ! stereocilium bundle +relationship: part_of GO:0043226 ! organelle + +[Term] +id: GO:0032421 +name: stereocilium bundle +namespace: cellular_component +def: "A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes." [GOC:ecd, PMID:15661519, PMID:7840137] +subset: goslim_pir +synonym: "stereocilia bundle" EXACT [] +is_a: GO:0098862 ! cluster of actin-based cell projections +relationship: has_part GO:0032420 ! stereocilium + +[Term] +id: GO:0032422 +name: purine-rich negative regulatory element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes." [GOC:mah, PMID:9819411] +synonym: "PNR element binding" BROAD [] +is_a: GO:0000976 ! transcription regulatory region sequence-specific DNA binding + +[Term] +id: GO:0032423 +name: regulation of mismatch repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mismatch repair." [GOC:vk] +is_a: GO:0006282 ! regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006298 ! mismatch repair +relationship: regulates GO:0006298 ! mismatch repair + +[Term] +id: GO:0032424 +name: negative regulation of mismatch repair +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair." [GOC:vk] +synonym: "down regulation of mismatch repair" EXACT [] +synonym: "down-regulation of mismatch repair" EXACT [] +synonym: "downregulation of mismatch repair" EXACT [] +synonym: "inhibition of mismatch repair" NARROW [] +is_a: GO:0032423 ! regulation of mismatch repair +is_a: GO:0045738 ! negative regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006298 ! mismatch repair +relationship: negatively_regulates GO:0006298 ! mismatch repair + +[Term] +id: GO:0032425 +name: positive regulation of mismatch repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mismatch repair." [GOC:vk] +synonym: "activation of mismatch repair" NARROW [] +synonym: "stimulation of mismatch repair" NARROW [] +synonym: "up regulation of mismatch repair" EXACT [] +synonym: "up-regulation of mismatch repair" EXACT [] +synonym: "upregulation of mismatch repair" EXACT [] +is_a: GO:0032423 ! regulation of mismatch repair +is_a: GO:0045739 ! positive regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006298 ! mismatch repair +relationship: positively_regulates GO:0006298 ! mismatch repair + +[Term] +id: GO:0032426 +name: stereocilium tip +namespace: cellular_component +def: "A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation." [GOC:ecd, GOC:krc, PMID:17021180, PMID:27565685] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032420 ! stereocilium + +[Term] +id: GO:0032427 +name: GBD domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac." [GOC:mah, GOC:pg, PMID:9119069] +synonym: "Cdc42/Rac interactive binding motif binding" EXACT [PMID:9119069] +synonym: "CRIB motif binding" EXACT [PMID:9119069] +synonym: "P21-Rho-binding domain binding" EXACT [GOC:rl] +synonym: "PMD binding" EXACT [GOC:rl] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0032428 +name: beta-N-acetylgalactosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides." [EC:3.2.1.53] +xref: EC:3.2.1.53 +xref: MetaCyc:3.2.1.53-RXN +is_a: GO:0004563 ! beta-N-acetylhexosaminidase activity + +[Term] +id: GO:0032429 +name: regulation of phospholipase A2 activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme phospholipase A2." [GOC:mah] +is_a: GO:0010517 ! regulation of phospholipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004623 ! phospholipase A2 activity +relationship: regulates GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0032430 +name: positive regulation of phospholipase A2 activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme phospholipase A2." [GOC:mah] +synonym: "activation of phospholipase A2 activity" NARROW [] +synonym: "stimulation of phospholipase A2 activity" NARROW [] +synonym: "up regulation of phospholipase A2 activity" EXACT [] +synonym: "up-regulation of phospholipase A2 activity" EXACT [] +synonym: "upregulation of phospholipase A2 activity" EXACT [] +is_a: GO:0010518 ! positive regulation of phospholipase activity +is_a: GO:0032429 ! regulation of phospholipase A2 activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004623 ! phospholipase A2 activity +relationship: positively_regulates GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0032431 +name: activation of phospholipase A2 activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme phospholipase A2." [GOC:mah] +synonym: "phospholipase A2 activation" EXACT [] +is_a: GO:0032430 ! positive regulation of phospholipase A2 activity + +[Term] +id: GO:0032432 +name: actin filament bundle +namespace: cellular_component +alt_id: GO:0000141 +alt_id: GO:0030482 +def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] +synonym: "actin cable" RELATED [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005884 ! actin filament +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0032433 +name: filopodium tip +namespace: cellular_component +def: "The end of a filopodium distal to the body of the cell." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030175 ! filopodium + +[Term] +id: GO:0032434 +name: regulation of proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] +is_a: GO:0061136 ! regulation of proteasomal protein catabolic process +is_a: GO:2000058 ! regulation of ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +relationship: regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0032435 +name: negative regulation of proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] +synonym: "down regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "down-regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "downregulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "inhibition of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1901799 ! negative regulation of proteasomal protein catabolic process +is_a: GO:2000059 ! negative regulation of ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +relationship: negatively_regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0032436 +name: positive regulation of proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] +synonym: "activation of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "stimulation of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "up regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "up-regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "upregulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1901800 ! positive regulation of proteasomal protein catabolic process +is_a: GO:2000060 ! positive regulation of ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +relationship: positively_regulates GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process + +[Term] +id: GO:0032437 +name: cuticular plate +namespace: cellular_component +def: "A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted." [PMID:12485990, PMID:2592408, PMID:8071151] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030864 ! cortical actin cytoskeleton + +[Term] +id: GO:0032438 +name: melanosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored." [GOC:vk] +synonym: "melanosome organisation" EXACT [GOC:mah] +synonym: "melanosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0048753 ! pigment granule organization + +[Term] +id: GO:0032440 +name: 2-alkenal reductase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+." [EC:1.3.1.74, PMID:16299173] +synonym: "n-alkanal:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.3.1.74] +synonym: "NAD(P)H-dependent alkenal/one oxidoreductase activity" EXACT [EC:1.3.1.74] +xref: EC:1.3.1.74 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0032441 +name: pheophorbide a oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O." [PMID:14657372, PMID:16448336] +xref: EC:1.14.15.17 +xref: MetaCyc:RXN-7740 +xref: RHEA:48140 +is_a: GO:0016730 ! oxidoreductase activity, acting on iron-sulfur proteins as donors + +[Term] +id: GO:0032442 +name: phenylcoumaran benzylic ether reductase activity +namespace: molecular_function +def: "Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+." [PMID:11030549, PMID:13129921] +synonym: "PCBER activity" EXACT [] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0032443 +name: regulation of ergosterol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol." [GOC:mah] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0106118 ! regulation of sterol biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006696 ! ergosterol biosynthetic process +relationship: regulates GO:0006696 ! ergosterol biosynthetic process + +[Term] +id: GO:0032444 +name: activin responsive factor complex +namespace: cellular_component +def: "A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor." [PMID:12374795, PMID:9288972] +comment: Note that this term should not be confused with any of the molecular function and biological process terms that refer to the small GTPase ARF (ADP-ribosylation factor). +synonym: "ARF complex" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0032445 +name: fructose import +namespace: biological_process +def: "The directed movement of the hexose monosaccharide fructose into a cell or organelle." [GOC:mah] +synonym: "fructose uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015755 ! fructose transmembrane transport + +[Term] +id: GO:0032446 +name: protein modification by small protein conjugation +namespace: biological_process +def: "A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein." [GOC:mah] +is_a: GO:0070647 ! protein modification by small protein conjugation or removal + +[Term] +id: GO:0032447 +name: protein urmylation +namespace: biological_process +def: "Covalent attachment of the ubiquitin-like protein URM1 to another protein." [GOC:vw] +is_a: GO:0032446 ! protein modification by small protein conjugation + +[Term] +id: GO:0032448 +name: DNA hairpin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences." [GOC:mah, ISBN:0198506732] +is_a: GO:0000217 ! DNA secondary structure binding + +[Term] +id: GO:0032449 +name: CBM complex +namespace: cellular_component +def: "A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation." [PMID:12909454] +synonym: "CARMA1-BCL10-Malt1 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032450 +name: maltose alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose." [MetaCyc:RXN-2141] +synonym: "maltase activity" EXACT [] +xref: EC:3.2.1.20 +xref: MetaCyc:RXN-2141 +is_a: GO:0004558 ! alpha-1,4-glucosidase activity +relationship: part_of GO:0000023 ! maltose metabolic process + +[Term] +id: GO:0032451 +name: demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from a substrate." [GOC:mah] +subset: goslim_pir +is_a: GO:0003824 ! catalytic activity +relationship: part_of GO:0070988 ! demethylation + +[Term] +id: GO:0032452 +name: histone demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from a histone." [GOC:mah] +xref: Reactome:R-HSA-3214912 "KDM1A, KDM1B demethylate MeK5-histone H3" +xref: Reactome:R-HSA-4722133 "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3" +xref: Reactome:R-HSA-4724279 "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3" +xref: Reactome:R-HSA-4724284 "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3" +xref: Reactome:R-HSA-4754176 "JMJD6 demethylates MeR3-histone H3" +xref: Reactome:R-HSA-4754181 "KDM5A-D demethylate Me2K5-histone H3" +xref: Reactome:R-HSA-4754187 "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3" +xref: Reactome:R-HSA-5423117 "PHF8 demethylates MeK21-histone H4" +xref: Reactome:R-HSA-5625797 "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters" +xref: Reactome:R-HSA-5625848 "KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters" +xref: Reactome:R-HSA-5625870 "KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters" +xref: Reactome:R-HSA-5661114 "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3" +xref: Reactome:R-HSA-5661115 "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3" +xref: Reactome:R-HSA-5661116 "KDM5A-D demethylate Me3K5-histone H3" +xref: Reactome:R-HSA-5661120 "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3" +xref: Reactome:R-HSA-5661121 "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3" +xref: Reactome:R-HSA-5661122 "JMJD6 demethylates Me2R3-histone H3" +xref: Reactome:R-HSA-5661123 "KDM1A, KDM1B demethylate Me2K5-histone H3" +xref: Reactome:R-HSA-5661124 "JMJD6 demethylates MeR4-HIST1H4" +xref: Reactome:R-HSA-5661125 "JMJD6 demethylates Me2sR4-HIST1H4" +is_a: GO:0140457 ! protein demethylase activity +relationship: part_of GO:0016577 ! histone demethylation + +[Term] +id: GO:0032453 +name: histone demethylase activity (H3-K4 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein." [GOC:mah] +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0034720 ! histone H3-K4 demethylation + +[Term] +id: GO:0032454 +name: histone demethylase activity (H3-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein." [PMID:16362057] +xref: EC:1.14.11.65 +xref: EC:1.14.11.66 +xref: Reactome:R-HSA-9011949 "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers" +xref: Reactome:R-HSA-9011985 "KDM1A demethylates H3 on MYC and BCL genes in response to estrogen" +xref: Reactome:R-HSA-997263 "JMJD1C demethylates H3K9 mono- and di-methylation" +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0033169 ! histone H3-K9 demethylation + +[Term] +id: GO:0032455 +name: nerve growth factor processing +namespace: biological_process +def: "The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor." [GOC:mah, PMID:8615794] +synonym: "beta-nerve growth factor processing" EXACT [PR:000011194] +synonym: "NGF processing" EXACT [PR:000011194] +is_a: GO:0016486 ! peptide hormone processing + +[Term] +id: GO:0032456 +name: endocytic recycling +namespace: biological_process +def: "The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635] +synonym: "retrograde transport of endocytic vesicles" RELATED [] +is_a: GO:0016197 ! endosomal transport + +[Term] +id: GO:0032457 +name: fast endocytic recycling +namespace: biological_process +def: "The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635] +synonym: "direct endocytic recycling" EXACT [] +is_a: GO:0032456 ! endocytic recycling + +[Term] +id: GO:0032458 +name: slow endocytic recycling +namespace: biological_process +def: "The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport." [GOC:ecd, PMID:16473635] +is_a: GO:0032456 ! endocytic recycling + +[Term] +id: GO:0032459 +name: regulation of protein oligomerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein oligomerization." [GOC:mah] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051259 ! protein complex oligomerization +relationship: regulates GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0032460 +name: negative regulation of protein oligomerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization." [GOC:mah] +synonym: "down regulation of protein oligomerization" EXACT [] +synonym: "down-regulation of protein oligomerization" EXACT [] +synonym: "downregulation of protein oligomerization" EXACT [] +synonym: "inhibition of protein oligomerization" NARROW [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0032459 ! regulation of protein oligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051259 ! protein complex oligomerization +relationship: negatively_regulates GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0032461 +name: positive regulation of protein oligomerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein oligomerization." [GOC:mah] +synonym: "activation of protein oligomerization" NARROW [] +synonym: "induction of protein oligomerization" RELATED [] +synonym: "stimulation of protein oligomerization" NARROW [] +synonym: "up regulation of protein oligomerization" EXACT [] +synonym: "up-regulation of protein oligomerization" EXACT [] +synonym: "upregulation of protein oligomerization" EXACT [] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0032459 ! regulation of protein oligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051259 ! protein complex oligomerization +relationship: positively_regulates GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0032462 +name: regulation of protein homooligomerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein homooligomerization." [GOC:mah] +is_a: GO:0032459 ! regulation of protein oligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051260 ! protein homooligomerization +relationship: regulates GO:0051260 ! protein homooligomerization + +[Term] +id: GO:0032463 +name: negative regulation of protein homooligomerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization." [GOC:mah] +synonym: "down regulation of protein homooligomerization" EXACT [] +synonym: "down-regulation of protein homooligomerization" EXACT [] +synonym: "downregulation of protein homooligomerization" EXACT [] +synonym: "inhibition of protein homooligomerization" NARROW [] +is_a: GO:0032460 ! negative regulation of protein oligomerization +is_a: GO:0032462 ! regulation of protein homooligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051260 ! protein homooligomerization +relationship: negatively_regulates GO:0051260 ! protein homooligomerization + +[Term] +id: GO:0032464 +name: positive regulation of protein homooligomerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein homooligomerization." [GOC:mah] +synonym: "activation of protein homooligomerization" NARROW [] +synonym: "induction of protein homooligomerization" RELATED [] +synonym: "stimulation of protein homooligomerization" NARROW [] +synonym: "up regulation of protein homooligomerization" EXACT [] +synonym: "up-regulation of protein homooligomerization" EXACT [] +synonym: "upregulation of protein homooligomerization" EXACT [] +is_a: GO:0032461 ! positive regulation of protein oligomerization +is_a: GO:0032462 ! regulation of protein homooligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051260 ! protein homooligomerization +relationship: positively_regulates GO:0051260 ! protein homooligomerization + +[Term] +id: GO:0032465 +name: regulation of cytokinesis +namespace: biological_process +alt_id: GO:0071775 +def: "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:mah] +synonym: "regulation of cell cycle cytokinesis" EXACT [] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000910 ! cytokinesis +relationship: regulates GO:0000910 ! cytokinesis + +[Term] +id: GO:0032466 +name: negative regulation of cytokinesis +namespace: biological_process +alt_id: GO:0071776 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah] +synonym: "down regulation of cytokinesis" EXACT [] +synonym: "down-regulation of cytokinesis" EXACT [] +synonym: "downregulation of cytokinesis" EXACT [] +synonym: "inhibition of cytokinesis" NARROW [] +synonym: "negative regulation of cell cycle cytokinesis" RELATED [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0032465 ! regulation of cytokinesis +is_a: GO:0051782 ! negative regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000910 ! cytokinesis +relationship: negatively_regulates GO:0000910 ! cytokinesis + +[Term] +id: GO:0032467 +name: positive regulation of cytokinesis +namespace: biological_process +alt_id: GO:0071777 +def: "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." [GOC:mah] +synonym: "activation of cytokinesis" NARROW [] +synonym: "positive regulation of cell cycle cytokinesis" RELATED [] +synonym: "stimulation of cytokinesis" NARROW [] +synonym: "up regulation of cytokinesis" EXACT [] +synonym: "up-regulation of cytokinesis" EXACT [] +synonym: "upregulation of cytokinesis" EXACT [] +is_a: GO:0032465 ! regulation of cytokinesis +is_a: GO:0051781 ! positive regulation of cell division +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000910 ! cytokinesis +relationship: positively_regulates GO:0000910 ! cytokinesis + +[Term] +id: GO:0032468 +name: Golgi calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings." [GOC:mah] +synonym: "calcium ion homeostasis in Golgi" EXACT [] +synonym: "Golgi calcium ion concentration regulation" EXACT [] +synonym: "regulation of calcium ion concentration in Golgi" EXACT [] +synonym: "regulation of Golgi calcium ion concentration" EXACT [] +is_a: GO:0006874 ! cellular calcium ion homeostasis +intersection_of: GO:0055074 ! calcium ion homeostasis +intersection_of: occurs_in GO:0005794 ! Golgi apparatus +relationship: occurs_in GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0032469 +name: endoplasmic reticulum calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings." [GOC:mah] +synonym: "calcium ion homeostasis in endoplasmic reticulum" EXACT [] +synonym: "calcium ion homeostasis in ER" EXACT [] +synonym: "endoplasmic reticulum calcium ion concentration regulation" EXACT [] +synonym: "ER calcium ion concentration regulation" EXACT [] +synonym: "ER calcium ion homeostasis" EXACT [] +synonym: "regulation of calcium ion concentration in endoplasmic reticulum" EXACT [] +synonym: "regulation of calcium ion concentration in ER" EXACT [] +synonym: "regulation of endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "regulation of ER calcium ion concentration" EXACT [] +is_a: GO:0006874 ! cellular calcium ion homeostasis +intersection_of: GO:0055074 ! calcium ion homeostasis +intersection_of: occurs_in GO:0005783 ! endoplasmic reticulum +relationship: occurs_in GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0032470 +name: positive regulation of endoplasmic reticulum calcium ion concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the endoplasmic reticulum." [GOC:mah] +synonym: "elevation of calcium ion concentration in endoplasmic reticulum" EXACT [] +synonym: "elevation of endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "elevation of ER calcium ion concentration" EXACT [] +synonym: "endoplasmic reticulum calcium ion concentration elevation" EXACT [] +is_a: GO:0032469 ! endoplasmic reticulum calcium ion homeostasis + +[Term] +id: GO:0032471 +name: negative regulation of endoplasmic reticulum calcium ion concentration +namespace: biological_process +def: "Any process that decreases the concentration of calcium ions in the endoplasmic reticulum." [GOC:mah] +synonym: "endoplasmic reticulum calcium ion concentration reduction" EXACT [] +synonym: "ER calcium ion concentration reduction" EXACT [] +synonym: "reduction of calcium ion concentration in endoplasmic reticulum" EXACT [] +synonym: "reduction of calcium ion concentration in ER" EXACT [] +synonym: "reduction of endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "reduction of ER calcium ion concentration" EXACT [] +is_a: GO:0032469 ! endoplasmic reticulum calcium ion homeostasis + +[Term] +id: GO:0032472 +name: Golgi calcium ion transport +namespace: biological_process +def: "The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus." [GOC:mah] +synonym: "Golgi calcium transport" EXACT [] +is_a: GO:0006816 ! calcium ion transport + +[Term] +id: GO:0032473 +name: cytoplasmic side of mitochondrial outer membrane +namespace: cellular_component +def: "The external (cytoplasmic) face of the mitochondrial outer membrane." [GOC:mah] +comment: In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane. +synonym: "cytosolic side of mitochondrial outer membrane" EXACT [] +synonym: "external leaflet of mitochondrial outer membrane" EXACT [GOC:ab] +synonym: "external side of mitochondrial envelope" RELATED [] +synonym: "external side of mitochondrial outer membrane" EXACT [] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0005741 ! mitochondrial outer membrane + +[Term] +id: GO:0032474 +name: otolith morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of an otolith are generated and organized." [GOC:dgh] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042472 ! inner ear morphogenesis +relationship: part_of GO:0048840 ! otolith development + +[Term] +id: GO:0032475 +name: otolith formation +namespace: biological_process +def: "The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dgh] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0032474 ! otolith morphogenesis + +[Term] +id: GO:0032476 +name: decaprenyl diphosphate synthase complex +namespace: cellular_component +def: "A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [GOC:mah, PMID:14519123] +subset: goslim_pir +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0032477 +name: homodimeric decaprenyl diphosphate synthase complex +namespace: cellular_component +def: "A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [PMID:14519123] +is_a: GO:0032476 ! decaprenyl diphosphate synthase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032478 +name: heterotetrameric decaprenyl diphosphate synthase complex +namespace: cellular_component +def: "A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1." [PMID:14519123] +is_a: GO:0032476 ! decaprenyl diphosphate synthase complex +is_a: GO:0098800 ! inner mitochondrial membrane protein complex + +[Term] +id: GO:0032479 +name: regulation of type I interferon production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah] +synonym: "regulation of type I IFN production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032606 ! type I interferon production +relationship: regulates GO:0032606 ! type I interferon production + +[Term] +id: GO:0032480 +name: negative regulation of type I interferon production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah] +synonym: "down regulation of type I interferon production" EXACT [] +synonym: "down-regulation of type I interferon production" EXACT [] +synonym: "downregulation of type I interferon production" EXACT [] +synonym: "inhibition of type I interferon production" NARROW [] +synonym: "negative regulation of type I IFN production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032479 ! regulation of type I interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032606 ! type I interferon production +relationship: negatively_regulates GO:0032606 ! type I interferon production + +[Term] +id: GO:0032481 +name: positive regulation of type I interferon production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:mah] +synonym: "activation of type I interferon production" NARROW [] +synonym: "positive regulation of type I IFN production" EXACT [] +synonym: "stimulation of type I interferon production" NARROW [] +synonym: "up regulation of type I interferon production" EXACT [] +synonym: "up-regulation of type I interferon production" EXACT [] +synonym: "upregulation of type I interferon production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032479 ! regulation of type I interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032606 ! type I interferon production +relationship: positively_regulates GO:0032606 ! type I interferon production + +[Term] +id: GO:0032482 +name: Rab protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state." [GOC:mah] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0032483 +name: regulation of Rab protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rab protein signal transduction." [GOC:mah] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032482 ! Rab protein signal transduction +relationship: regulates GO:0032482 ! Rab protein signal transduction + +[Term] +id: GO:0032484 +name: Ral protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state." [GOC:mah] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0032485 +name: regulation of Ral protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Ral protein signal transduction." [GOC:mah] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032484 ! Ral protein signal transduction +relationship: regulates GO:0032484 ! Ral protein signal transduction + +[Term] +id: GO:0032486 +name: Rap protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state." [GOC:mah] +is_a: GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0032487 +name: regulation of Rap protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rap protein signal transduction." [GOC:mah] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032486 ! Rap protein signal transduction +relationship: regulates GO:0032486 ! Rap protein signal transduction + +[Term] +id: GO:0032488 +name: Cdc42 protein signal transduction +namespace: biological_process +def: "A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state." [GOC:mah, PMID:18558478] +synonym: "Cdc42 signaling" RELATED [GOC:vw] +synonym: "Cdc42 signaling pathway" RELATED [GOC:vw] +synonym: "cdc42 signalling pathway" RELATED [GOC:vw] +is_a: GO:0007266 ! Rho protein signal transduction + +[Term] +id: GO:0032489 +name: regulation of Cdc42 protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction." [GOC:mah] +is_a: GO:0035023 ! regulation of Rho protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032488 ! Cdc42 protein signal transduction +relationship: regulates GO:0032488 ! Cdc42 protein signal transduction + +[Term] +id: GO:0032490 +name: detection of molecule of bacterial origin +namespace: biological_process +def: "The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal." [GOC:add, GOC:rl] +synonym: "detection of bacteria associated molecule" EXACT [] +synonym: "detection of bacterial associated molecule" EXACT [] +synonym: "detection of bacterium associated molecule" EXACT [] +is_a: GO:0002237 ! response to molecule of bacterial origin +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0098581 ! detection of external biotic stimulus + +[Term] +id: GO:0032491 +name: detection of molecule of fungal origin +namespace: biological_process +def: "The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal." [GOC:mah, GOC:rl] +synonym: "detection of fungal associated molecule" EXACT [] +synonym: "detection of fungus associated molecule" EXACT [] +is_a: GO:0002238 ! response to molecule of fungal origin +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0098581 ! detection of external biotic stimulus + +[Term] +id: GO:0032492 +name: detection of molecule of oomycetes origin +namespace: biological_process +def: "The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal." [GOC:mah, GOC:rl] +synonym: "detection of oomycetes associated molecule" EXACT [] +is_a: GO:0002240 ! response to molecule of oomycetes origin +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0098581 ! detection of external biotic stimulus + +[Term] +id: GO:0032493 +name: response to bacterial lipoprotein +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus." [GOC:add, PMID:12077222] +is_a: GO:0002237 ! response to molecule of bacterial origin + +[Term] +id: GO:0032494 +name: response to peptidoglycan +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule." [GOC:add, ISBN:0721601464] +is_a: GO:0002237 ! response to molecule of bacterial origin +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0032495 +name: response to muramyl dipeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan." [GOC:add] +is_a: GO:0042493 ! response to drug +is_a: GO:1901652 ! response to peptide + +[Term] +id: GO:0032496 +name: response to lipopolysaccharide +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." [GOC:add, ISBN:0721601464] +synonym: "response to endotoxin" BROAD [GOC:sl] +synonym: "response to LPS" EXACT [] +is_a: GO:0002237 ! response to molecule of bacterial origin +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0032497 +name: detection of lipopolysaccharide +namespace: biological_process +def: "The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." [GOC:add, PMID:15998797] +synonym: "detection of LPS" EXACT [] +is_a: GO:0032490 ! detection of molecule of bacterial origin +is_a: GO:0032496 ! response to lipopolysaccharide + +[Term] +id: GO:0032498 +name: detection of muramyl dipeptide +namespace: biological_process +def: "The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan." [GOC:rl, PMID:15998797] +is_a: GO:0032495 ! response to muramyl dipeptide +is_a: GO:0032499 ! detection of peptidoglycan + +[Term] +id: GO:0032499 +name: detection of peptidoglycan +namespace: biological_process +def: "The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule." [GOC:add, ISBN:0721601464] +is_a: GO:0032490 ! detection of molecule of bacterial origin +is_a: GO:0032494 ! response to peptidoglycan + +[Term] +id: GO:0032500 +name: muramyl dipeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan." [GOC:rl] +is_a: GO:0008144 ! drug binding +is_a: GO:0042277 ! peptide binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0032501 +name: multicellular organismal process +namespace: biological_process +alt_id: GO:0044707 +alt_id: GO:0050874 +def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] +subset: goslim_pir +synonym: "organismal physiological process" EXACT [] +synonym: "single-multicellular organism process" RELATED [] +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 +created_by: jl +creation_date: 2012-09-19T16:07:47Z + +[Term] +id: GO:0032502 +name: developmental process +namespace: biological_process +alt_id: GO:0044767 +def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] +subset: goslim_agr +subset: goslim_aspergillus +subset: goslim_flybase_ribbon +subset: goslim_pir +synonym: "development" NARROW [] +synonym: "single-organism developmental process" RELATED [] +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +created_by: jl +creation_date: 2012-12-19T12:21:31Z + +[Term] +id: GO:0032504 +name: multicellular organism reproduction +namespace: biological_process +def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] +is_a: GO:0000003 ! reproduction +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0032505 +name: reproduction of a single-celled organism +namespace: biological_process +def: "The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete] +is_a: GO:0000003 ! reproduction + +[Term] +id: GO:0032506 +name: cytokinetic process +namespace: biological_process +def: "A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells)." [GOC:bf, GOC:isa_complete, GOC:mah] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0000910 ! cytokinesis + +[Term] +id: GO:0032507 +name: maintenance of protein location in cell +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." [GOC:isa_complete, GOC:mah] +synonym: "maintenance of protein localization in cell" RELATED [GOC:dph, GOC:tb] +is_a: GO:0045185 ! maintenance of protein location +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0034613 ! cellular protein localization + +[Term] +id: GO:0032508 +name: DNA duplex unwinding +namespace: biological_process +def: "The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands." [GOC:isa_complete, GOC:mah] +comment: Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'. +synonym: "DNA unwinding" EXACT [] +synonym: "duplex DNA melting" EXACT [] +is_a: GO:0032392 ! DNA geometric change + +[Term] +id: GO:0032509 +name: endosome transport via multivesicular body sorting pathway +namespace: biological_process +def: "The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment." [GOC:mah, PMID:12461556, PMID:16689637] +synonym: "endosome transport via MVB sorting pathway" EXACT [] +is_a: GO:0016197 ! endosomal transport +is_a: GO:0071985 ! multivesicular body sorting pathway + +[Term] +id: GO:0032510 +name: endosome to lysosome transport via multivesicular body sorting pathway +namespace: biological_process +def: "The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome." [GOC:mah, PMID:12461556, PMID:16689637] +synonym: "endosome to lysosome transport via MVB sorting pathway" EXACT [] +is_a: GO:0008333 ! endosome to lysosome transport +is_a: GO:0032509 ! endosome transport via multivesicular body sorting pathway + +[Term] +id: GO:0032511 +name: late endosome to vacuole transport via multivesicular body sorting pathway +namespace: biological_process +def: "The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole." [GOC:mah, PMID:12461556, PMID:16689637] +synonym: "endosome to vacuole transport via MVB sorting pathway" EXACT [] +is_a: GO:0032509 ! endosome transport via multivesicular body sorting pathway +is_a: GO:0045324 ! late endosome to vacuole transport + +[Term] +id: GO:0032515 +name: negative regulation of phosphoprotein phosphatase activity +namespace: biological_process +alt_id: GO:0032513 +alt_id: GO:0034048 +def: "Any process that stops or reduces the activity of a phosphoprotein phosphatase." [GOC:mah] +synonym: "down regulation of calcineurin activity" NARROW [GOC:dph, GOC:rl] +synonym: "down regulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "down regulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "down regulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "down regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "down regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "down-regulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "down-regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "down-regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "downregulation of calcineurin activity" NARROW [GOC:dph, GOC:rl] +synonym: "downregulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "downregulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "downregulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "downregulation of protein phosphatase type 2A activity" NARROW [] +synonym: "downregulation of protein phosphatase type 2B activity" NARROW [] +synonym: "inhibition of calcineurin activity" NARROW [GOC:dph, GOC:rl] +synonym: "inhibition of phosphoprotein phosphatase activity" NARROW [] +synonym: "inhibition of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "inhibition of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "inhibition of protein phosphatase type 2A activity" NARROW [] +synonym: "inhibition of protein phosphatase type 2B activity" NARROW [] +synonym: "negative regulation of calcineurin activity" NARROW [] +synonym: "negative regulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "negative regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "negative regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "regulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +is_a: GO:0010923 ! negative regulation of phosphatase activity +is_a: GO:0035308 ! negative regulation of protein dephosphorylation +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004721 ! phosphoprotein phosphatase activity +relationship: negatively_regulates GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0032516 +name: positive regulation of phosphoprotein phosphatase activity +namespace: biological_process +alt_id: GO:0032514 +alt_id: GO:0034049 +def: "Any process that activates or increases the activity of a phosphoprotein phosphatase." [GOC:mah] +synonym: "activation of calcineurin activity" NARROW [GOC:dph, GOC:rl] +synonym: "activation of phosphoprotein phosphatase activity" NARROW [] +synonym: "activation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "activation of protein phosphatase type 2A activity" NARROW [] +synonym: "activation of protein phosphatase type 2B activity" NARROW [] +synonym: "calcineurin activation" NARROW [] +synonym: "positive regulation of calcineurin activity" NARROW [] +synonym: "positive regulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "positive regulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "positive regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "positive regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "stimulation of phosphoprotein phosphatase activity" NARROW [] +synonym: "stimulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "stimulation of protein phosphatase type 2A activity" NARROW [] +synonym: "stimulation of protein phosphatase type 2B activity" NARROW [] +synonym: "up regulation of calcineurin activity" NARROW [GOC:dph, GOC:rl] +synonym: "up regulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "up regulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "up regulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "up regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "up regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "up-regulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "up-regulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "up-regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "up-regulation of protein phosphatase type 2B activity" NARROW [] +synonym: "upregulation of phosphoprotein phosphatase activity" EXACT [] +synonym: "upregulation of protein phosphatase 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "upregulation of protein phosphatase type 2A activity" NARROW [] +synonym: "upregulation of protein phosphatase type 2B activity" NARROW [] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:0035307 ! positive regulation of protein dephosphorylation +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004721 ! phosphoprotein phosphatase activity +relationship: positively_regulates GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0032517 +name: SOD1-calcineurin complex +namespace: cellular_component +def: "A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1." [GOC:mah, PMID:17324120] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032523 +name: silicon efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane." [GOC:mah, PMID:17625566] +synonym: "silicon efflux transporter activity" EXACT [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity + +[Term] +id: GO:0032524 +name: obsolete nutrient export +namespace: biological_process +def: "OBSOLETE. The directed movement of nutrients out of a cell or organelle." [GOC:mah] +comment: This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning. +synonym: "nutrient export" EXACT [] +is_obsolete: true +consider: GO:0006810 + +[Term] +id: GO:0032525 +name: somite rostral/caudal axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary." [GOC:bf, PMID:16326386, PMID:17360776] +synonym: "somite rostrocaudal axis specification" EXACT [] +synonym: "somite rostrocaudal polarity" RELATED [] +is_a: GO:0000578 ! embryonic axis specification +is_a: GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0001756 ! somitogenesis + +[Term] +id: GO:0032526 +name: response to retinoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus." [GOC:sl] +synonym: "response to vitamin A acid" EXACT [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0032527 +name: protein exit from endoplasmic reticulum +namespace: biological_process +def: "The directed movement of proteins from the endoplasmic reticulum." [GOC:rb] +synonym: "protein exit from ER" EXACT [] +synonym: "protein export from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "protein export from ER" EXACT [GOC:mah] +is_a: GO:0006886 ! intracellular protein transport +relationship: occurs_in GO:0005737 ! cytoplasm + +[Term] +id: GO:0032528 +name: microvillus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah] +synonym: "microvillus organisation" EXACT [GOC:mah] +synonym: "microvillus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization + +[Term] +id: GO:0032529 +name: follicle cell microvillus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments." [GOC:sart, PMID:16507588] +synonym: "follicle cell microvillus organisation" EXACT [GOC:mah] +synonym: "follicle cell microvillus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0032528 ! microvillus organization + +[Term] +id: GO:0032530 +name: regulation of microvillus organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] +synonym: "regulation of microvillus organisation" EXACT [GOC:mah] +synonym: "regulation of microvillus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032528 ! microvillus organization +relationship: regulates GO:0032528 ! microvillus organization + +[Term] +id: GO:0032531 +name: regulation of follicle cell microvillus organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell." [GOC:mah] +synonym: "regulation of follicle cell microvillus organisation" EXACT [GOC:mah] +synonym: "regulation of follicle cell microvillus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0032530 ! regulation of microvillus organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032529 ! follicle cell microvillus organization +relationship: regulates GO:0032529 ! follicle cell microvillus organization + +[Term] +id: GO:0032532 +name: regulation of microvillus length +namespace: biological_process +def: "A process that modulates the length of a microvillus." [GOC:mah] +is_a: GO:0032530 ! regulation of microvillus organization +is_a: GO:0032536 ! regulation of cell projection size + +[Term] +id: GO:0032533 +name: regulation of follicle cell microvillus length +namespace: biological_process +def: "A process that modulates the length of a microvillus on a follicle cell." [GOC:sart, PMID:16260500] +is_a: GO:0008361 ! regulation of cell size +is_a: GO:0032531 ! regulation of follicle cell microvillus organization +is_a: GO:0032532 ! regulation of microvillus length + +[Term] +id: GO:0032534 +name: regulation of microvillus assembly +namespace: biological_process +def: "A process that modulates the formation of a microvillus." [GOC:mah] +synonym: "regulation of microvillus biogenesis" RELATED [GOC:mah] +is_a: GO:0032530 ! regulation of microvillus organization +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030033 ! microvillus assembly +relationship: regulates GO:0030033 ! microvillus assembly + +[Term] +id: GO:0032535 +name: regulation of cellular component size +namespace: biological_process +def: "A process that modulates the size of a cellular component." [GOC:mah] +is_a: GO:0016043 ! cellular component organization +is_a: GO:0090066 ! regulation of anatomical structure size + +[Term] +id: GO:0032536 +name: regulation of cell projection size +namespace: biological_process +def: "A process that modulates the size of a cell projection." [GOC:mah] +is_a: GO:0032535 ! regulation of cellular component size + +[Term] +id: GO:0032537 +name: host-seeking behavior +namespace: biological_process +def: "The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host." [GOC:mah, GOC:pr, PMID:11931033] +synonym: "host-seeking behaviour" EXACT [] +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0032538 +name: regulation of host-seeking behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah] +synonym: "regulation of host-seeking behaviour" EXACT [] +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032537 ! host-seeking behavior +relationship: regulates GO:0032537 ! host-seeking behavior + +[Term] +id: GO:0032539 +name: negative regulation of host-seeking behavior +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah] +synonym: "down regulation of host-seeking behavior" EXACT [] +synonym: "down-regulation of host-seeking behavior" EXACT [] +synonym: "downregulation of host-seeking behavior" EXACT [] +synonym: "inhibition of host-seeking behavior" NARROW [] +synonym: "negative regulation of host-seeking behaviour" EXACT [] +is_a: GO:0032538 ! regulation of host-seeking behavior +is_a: GO:0048521 ! negative regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032537 ! host-seeking behavior +relationship: negatively_regulates GO:0032537 ! host-seeking behavior + +[Term] +id: GO:0032540 +name: positive regulation of host-seeking behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism." [GOC:mah] +synonym: "activation of host-seeking behavior" NARROW [] +synonym: "positive regulation of host-seeking behaviour" EXACT [] +synonym: "stimulation of host-seeking behavior" NARROW [] +synonym: "up regulation of host-seeking behavior" EXACT [] +synonym: "up-regulation of host-seeking behavior" EXACT [] +synonym: "upregulation of host-seeking behavior" EXACT [] +is_a: GO:0032538 ! regulation of host-seeking behavior +is_a: GO:0048520 ! positive regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032537 ! host-seeking behavior +relationship: positively_regulates GO:0032537 ! host-seeking behavior + +[Term] +id: GO:0032541 +name: cortical endoplasmic reticulum +namespace: cellular_component +def: "A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements." [GOC:se, PMID:10931860, PMID:17686782] +comment: The dynamic nature of the cortical ER and the movements it undergoes (branching and ring closure) has been shown in both yeast and mammalian cells, so appears highly conserved. (PMID:10931860) +synonym: "cortical ER" EXACT [] +synonym: "ER-PM peripheral junction" BROAD [GOC:ans, PMID:21062895] +synonym: "peripheral endoplasmic reticulum" RELATED [] +synonym: "peripheral ER" RELATED [] +is_a: GO:0071782 ! endoplasmic reticulum tubular network +intersection_of: GO:0071782 ! endoplasmic reticulum tubular network +intersection_of: part_of GO:0005938 ! cell cortex +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0032542 +name: sulfiredoxin activity +namespace: molecular_function +def: "Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R." [EC:1.8.98.2, PMID:16102934] +synonym: "peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity" EXACT [] +synonym: "peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]" RELATED [EC:1.8.98.2] +synonym: "Srx1" RELATED [EC:1.8.98.2] +synonym: "sulphiredoxin activity" EXACT [] +xref: EC:1.8.98.2 +xref: MetaCyc:1.8.98.2-RXN +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0032543 +name: mitochondrial translation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." [GOC:go_curators] +subset: goslim_drosophila +subset: goslim_yeast +synonym: "mitochondrial protein anabolism" EXACT [] +synonym: "mitochondrial protein biosynthesis" EXACT [] +synonym: "mitochondrial protein formation" EXACT [] +synonym: "mitochondrial protein synthesis" EXACT [] +synonym: "mitochondrial protein translation" EXACT [] +is_a: GO:0006412 ! translation +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0005739 ! mitochondrion +intersection_of: part_of GO:0140053 ! mitochondrial gene expression +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0140053 ! mitochondrial gene expression + +[Term] +id: GO:0032544 +name: plastid translation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." [GOC:go_curators] +synonym: "plastid protein anabolism" EXACT [] +synonym: "plastid protein biosynthesis" EXACT [] +synonym: "plastid protein formation" EXACT [] +synonym: "plastid protein synthesis" EXACT [] +synonym: "plastid protein translation" EXACT [] +is_a: GO:0006412 ! translation +is_a: GO:0009657 ! plastid organization +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0009536 ! plastid +relationship: occurs_in GO:0009536 ! plastid +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0032545 +name: CURI complex +namespace: cellular_component +def: "A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p." [PMID:17452446] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032546 +name: deoxyribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose." [GOC:mah] +is_a: GO:0001882 ! nucleoside binding + +[Term] +id: GO:0032547 +name: purine deoxyribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose." [GOC:mah] +is_a: GO:0001883 ! purine nucleoside binding +is_a: GO:0032546 ! deoxyribonucleoside binding + +[Term] +id: GO:0032548 +name: pyrimidine deoxyribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose." [GOC:mah] +is_a: GO:0001884 ! pyrimidine nucleoside binding +is_a: GO:0032546 ! deoxyribonucleoside binding + +[Term] +id: GO:0032549 +name: ribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] +is_a: GO:0001882 ! nucleoside binding + +[Term] +id: GO:0032550 +name: purine ribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] +is_a: GO:0001883 ! purine nucleoside binding +is_a: GO:0032549 ! ribonucleoside binding + +[Term] +id: GO:0032551 +name: pyrimidine ribonucleoside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose." [GOC:mah] +is_a: GO:0001884 ! pyrimidine nucleoside binding +is_a: GO:0032549 ! ribonucleoside binding + +[Term] +id: GO:0032552 +name: deoxyribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0032553 +name: ribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0032554 +name: purine deoxyribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] +is_a: GO:0017076 ! purine nucleotide binding +is_a: GO:0032552 ! deoxyribonucleotide binding + +[Term] +id: GO:0032555 +name: purine ribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] +is_a: GO:0017076 ! purine nucleotide binding +is_a: GO:0032553 ! ribonucleotide binding + +[Term] +id: GO:0032556 +name: pyrimidine deoxyribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] +is_a: GO:0019103 ! pyrimidine nucleotide binding +is_a: GO:0032552 ! deoxyribonucleotide binding + +[Term] +id: GO:0032557 +name: pyrimidine ribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] +is_a: GO:0019103 ! pyrimidine nucleotide binding +is_a: GO:0032553 ! ribonucleotide binding + +[Term] +id: GO:0032558 +name: adenyl deoxyribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] +is_a: GO:0030554 ! adenyl nucleotide binding +is_a: GO:0032554 ! purine deoxyribonucleotide binding + +[Term] +id: GO:0032559 +name: adenyl ribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] +is_a: GO:0030554 ! adenyl nucleotide binding +is_a: GO:0032555 ! purine ribonucleotide binding + +[Term] +id: GO:0032560 +name: guanyl deoxyribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] +is_a: GO:0019001 ! guanyl nucleotide binding +is_a: GO:0032554 ! purine deoxyribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0032561 +name: guanyl ribonucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] +is_a: GO:0019001 ! guanyl nucleotide binding +is_a: GO:0032555 ! purine ribonucleotide binding + +[Term] +id: GO:0032562 +name: dAMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dAMP, deoxyadenosine monophosphate." [GOC:mah] +is_a: GO:0032558 ! adenyl deoxyribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0032563 +name: dADP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dADP, deoxyadenosine diphosphate." [GOC:mah] +is_a: GO:0032558 ! adenyl deoxyribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0032564 +name: dATP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate." [GOC:mah] +is_a: GO:0032558 ! adenyl deoxyribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0032565 +name: dGMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dGMP, deoxyguanosine monophosphate." [GOC:mah] +is_a: GO:0032560 ! guanyl deoxyribonucleotide binding + +[Term] +id: GO:0032566 +name: dGDP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dGDP, deoxyguanosine diphosphate." [GOC:mah] +is_a: GO:0032560 ! guanyl deoxyribonucleotide binding + +[Term] +id: GO:0032567 +name: dGTP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate." [GOC:mah] +is_a: GO:0032560 ! guanyl deoxyribonucleotide binding + +[Term] +id: GO:0032570 +name: response to progesterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus." [GOC:sl] +synonym: "response to progesterone stimulus" EXACT [GOC:dos] +is_a: GO:0042493 ! response to drug +is_a: GO:0048545 ! response to steroid hormone +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0032571 +name: response to vitamin K +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus." [GOC:sl] +is_a: GO:0033273 ! response to vitamin + +[Term] +id: GO:0032572 +name: response to menaquinone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus." [GOC:sl] +synonym: "response to menatetrenone" EXACT [] +synonym: "response to vitamin K2" EXACT [] +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0032573 +name: response to phylloquinone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus." [GOC:sl] +synonym: "response to vitamin K1" EXACT [] +is_a: GO:0033273 ! response to vitamin +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0032574 +name: 5'-3' RNA helicase activity +namespace: molecular_function +alt_id: GO:0032575 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'." [GOC:jp] +synonym: "5' to 3' RNA helicase activity" EXACT [] +synonym: "ATP-dependent 5' to 3' RNA helicase activity" EXACT [] +synonym: "ATP-dependent 5'-3' RNA helicase activity" EXACT [] +is_a: GO:0003724 ! RNA helicase activity + +[Term] +id: GO:0032576 +name: O-linoleoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule." [GOC:cb] +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0032577 +name: phosphatidylcholine:cardiolipin O-linoleoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule." [GOC:cb, GOC:mah] +synonym: "phosphatidylcholine:cardiolipin linoleoyltransferase" EXACT [] +is_a: GO:0032576 ! O-linoleoyltransferase activity + +[Term] +id: GO:0032578 +name: aleurone grain membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an aleurone grain." [GOC:ecd] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0033095 ! aleurone grain + +[Term] +id: GO:0032579 +name: apical lamina of hyaline layer +namespace: cellular_component +def: "A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms." [GOC:ecd, PMID:2060714, PMID:7608987, PMID:9638331] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0033166 ! hyaline layer + +[Term] +id: GO:0032580 +name: Golgi cisterna membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex." [GOC:ecd, GOC:mah] +synonym: "Golgi stack membrane" EXACT [] +is_a: GO:0000139 ! Golgi membrane +relationship: part_of GO:0031985 ! Golgi cisterna + +[Term] +id: GO:0032581 +name: ER-dependent peroxisome organization +namespace: biological_process +def: "A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum." [GOC:mah, PMID:16717127, PMID:17646399] +synonym: "endoplasmic reticulum-dependent peroxisome organization" EXACT [GOC:mah] +synonym: "ER-dependent peroxisome biogenesis" RELATED [GOC:mah] +synonym: "ER-dependent peroxisome organisation" EXACT [GOC:mah] +is_a: GO:0007031 ! peroxisome organization + +[Term] +id: GO:0032584 +name: growth cone membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a growth cone." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0030426 ! growth cone + +[Term] +id: GO:0032585 +name: multivesicular body membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a multivesicular body." [GOC:mah] +synonym: "multivesicular endosome membrane" EXACT [] +synonym: "MVB membrane" EXACT [] +synonym: "MVE membrane" EXACT [] +is_a: GO:0031902 ! late endosome membrane +relationship: part_of GO:0005771 ! multivesicular body + +[Term] +id: GO:0032586 +name: protein storage vacuole membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a protein storage vacuole." [GOC:mah] +is_a: GO:0009705 ! plant-type vacuole membrane + +[Term] +id: GO:0032587 +name: ruffle membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a ruffle." [GOC:mah] +synonym: "membrane ruffle" RELATED [] +is_a: GO:0031253 ! cell projection membrane +is_a: GO:0031256 ! leading edge membrane +relationship: part_of GO:0001726 ! ruffle + +[Term] +id: GO:0032588 +name: trans-Golgi network membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network." [GOC:mah] +synonym: "Golgi trans face membrane" RELATED [] +synonym: "trans Golgi network membrane" EXACT [] +is_a: GO:0000139 ! Golgi membrane +relationship: part_of GO:0005802 ! trans-Golgi network + +[Term] +id: GO:0032589 +name: neuron projection membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +is_a: GO:0031256 ! leading edge membrane +relationship: part_of GO:0043005 ! neuron projection + +[Term] +id: GO:0032590 +name: dendrite membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a dendrite." [GOC:mah] +is_a: GO:0032589 ! neuron projection membrane + +[Term] +id: GO:0032591 +name: dendritic spine membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a dendritic spine." [GOC:mah] +is_a: GO:0032589 ! neuron projection membrane +is_a: GO:0097060 ! synaptic membrane +relationship: part_of GO:0032590 ! dendrite membrane + +[Term] +id: GO:0032592 +name: integral component of mitochondrial membrane +namespace: cellular_component +def: "The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to mitochondrial membrane" NARROW [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0098573 ! intrinsic component of mitochondrial membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0031966 ! mitochondrial membrane + +[Term] +id: GO:0032593 +name: insulin-responsive compartment +namespace: cellular_component +def: "A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2." [PMID:17644329] +synonym: "GLUT4 storage compartment" EXACT [] +synonym: "GSC" RELATED [] +synonym: "IRC" RELATED [] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0032594 +name: protein transport within lipid bilayer +namespace: biological_process +def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah] +synonym: "protein translocation within membrane" EXACT [] +synonym: "receptor translocation within membrane" NARROW [] +synonym: "receptor transport within lipid bilayer" NARROW [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0051668 ! localization within membrane +is_a: GO:0061024 ! membrane organization +intersection_of: GO:0015031 ! protein transport +intersection_of: occurs_in GO:0016020 ! membrane + +[Term] +id: GO:0032595 +name: B cell receptor transport within lipid bilayer +namespace: biological_process +def: "The directed movement of a B cell receptor within a lipid bilayer." [GOC:mah] +synonym: "B cell receptor translocation within membrane" EXACT [] +synonym: "BCR translocation within membrane" EXACT [] +synonym: "BCR transport within lipid bilayer" EXACT [] +is_a: GO:0032594 ! protein transport within lipid bilayer + +[Term] +id: GO:0032596 +name: protein transport into membrane raft +namespace: biological_process +def: "The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:mah] +synonym: "protein translocation into membrane raft" EXACT [] +synonym: "protein transport into lipid raft" EXACT [] +synonym: "receptor translocation into membrane raft" NARROW [] +synonym: "receptor transport into membrane raft" NARROW [] +is_a: GO:0032594 ! protein transport within lipid bilayer +is_a: GO:0090150 ! establishment of protein localization to membrane +is_a: GO:1903044 ! protein localization to membrane raft + +[Term] +id: GO:0032597 +name: B cell receptor transport into membrane raft +namespace: biological_process +def: "The directed movement of a B cell receptor into a membrane raft." [GOC:mah] +synonym: "B cell receptor translocation into membrane raft" EXACT [] +synonym: "B cell receptor transport into lipid raft" EXACT [] +synonym: "BCR translocation into membrane raft" EXACT [] +synonym: "BCR transport into membrane raft" EXACT [] +is_a: GO:0032595 ! B cell receptor transport within lipid bilayer +is_a: GO:0032596 ! protein transport into membrane raft + +[Term] +id: GO:0032598 +name: B cell receptor transport into immunological synapse +namespace: biological_process +def: "The directed movement of a B cell receptor into an immunological synapse." [GOC:mah] +synonym: "B cell receptor translocation into immunological synapse" EXACT [] +synonym: "BCR translocation into immunological synapse" EXACT [] +synonym: "BCR transport into immunological synapse" EXACT [] +is_a: GO:0032597 ! B cell receptor transport into membrane raft + +[Term] +id: GO:0032599 +name: protein transport out of membrane raft +namespace: biological_process +def: "The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:mah] +synonym: "protein translocation out of membrane raft" EXACT [] +synonym: "protein transport out of lipid raft" EXACT [] +synonym: "receptor translocation out of membrane raft" NARROW [] +synonym: "receptor transport out of membrane raft" NARROW [] +is_a: GO:0032594 ! protein transport within lipid bilayer + +[Term] +id: GO:0032600 +name: chemokine receptor transport out of membrane raft +namespace: biological_process +def: "The directed movement of a chemokine receptor out of a membrane raft." [GOC:mah] +synonym: "chemokine receptor translocation out of membrane raft" EXACT [] +synonym: "chemokine receptor transport out of lipid raft" EXACT [] +is_a: GO:0032599 ! protein transport out of membrane raft +is_a: GO:0033606 ! chemokine receptor transport within lipid bilayer + +[Term] +id: GO:0032601 +name: connective tissue growth factor production +namespace: biological_process +def: "The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "CCN2 production" EXACT [] +synonym: "CTGF production" EXACT [] +synonym: "Fisp12 production" EXACT [] +synonym: "Hcs24 production" EXACT [] +synonym: "hypertrophic chondrocyte-specific gene product 24 production" EXACT [] +synonym: "IGFBP8 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032602 +name: chemokine production +namespace: biological_process +def: "The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032603 +name: fractalkine production +namespace: biological_process +def: "The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +is_a: GO:0032602 ! chemokine production + +[Term] +id: GO:0032604 +name: granulocyte macrophage colony-stimulating factor production +namespace: biological_process +def: "The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "GM-CSF production" EXACT [GOC:vk] +synonym: "granulocyte macrophage colony stimulating factor production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032605 +name: hepatocyte growth factor production +namespace: biological_process +def: "The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032606 +name: type I interferon production +namespace: biological_process +def: "The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834] +synonym: "interferon type I production" EXACT [] +synonym: "type I IFN production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032607 +name: interferon-alpha production +namespace: biological_process +def: "The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IFN-alpha production" EXACT [GOC:mah] +synonym: "IFNA production" EXACT [GOC:mah] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0032608 +name: interferon-beta production +namespace: biological_process +def: "The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IFN-beta production" EXACT [] +synonym: "IFNB production" EXACT [GOC:mah] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0032609 +name: interferon-gamma production +namespace: biological_process +def: "The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah] +synonym: "IFNG production" EXACT [GOC:mah] +synonym: "type II IFN production" BROAD [GOC:mah] +synonym: "type II interferon production" BROAD [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032610 +name: interleukin-1 alpha production +namespace: biological_process +def: "The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-1 alpha production" EXACT [] +is_a: GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0032611 +name: interleukin-1 beta production +namespace: biological_process +def: "The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-1 beta production" EXACT [] +is_a: GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0032612 +name: interleukin-1 production +namespace: biological_process +def: "The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-1 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032613 +name: interleukin-10 production +namespace: biological_process +def: "The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-10 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032614 +name: interleukin-11 production +namespace: biological_process +def: "The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-11 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032615 +name: interleukin-12 production +namespace: biological_process +def: "The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-12 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032616 +name: interleukin-13 production +namespace: biological_process +def: "The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-13 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032617 +name: interleukin-14 production +namespace: biological_process +def: "The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-14 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032618 +name: interleukin-15 production +namespace: biological_process +def: "The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-15 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032619 +name: interleukin-16 production +namespace: biological_process +def: "The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-16 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032620 +name: interleukin-17 production +namespace: biological_process +def: "The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah, GOC:rv, PR:000001092, Wikipedia:Interleukin_17] +synonym: "IL-17 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032621 +name: interleukin-18 production +namespace: biological_process +def: "The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-18 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032622 +name: interleukin-19 production +namespace: biological_process +def: "The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-19 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032623 +name: interleukin-2 production +namespace: biological_process +def: "The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-2 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032624 +name: interleukin-20 production +namespace: biological_process +def: "The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-20 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032625 +name: interleukin-21 production +namespace: biological_process +def: "The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-21 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032626 +name: interleukin-22 production +namespace: biological_process +def: "The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-22 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032627 +name: interleukin-23 production +namespace: biological_process +def: "The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-23 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032628 +name: interleukin-24 production +namespace: biological_process +def: "The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-24 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032629 +name: interleukin-25 production +namespace: biological_process +def: "The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-25 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032630 +name: interleukin-26 production +namespace: biological_process +def: "The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-26 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032631 +name: interleukin-27 production +namespace: biological_process +def: "The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-27 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032632 +name: interleukin-3 production +namespace: biological_process +def: "The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-3 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032633 +name: interleukin-4 production +namespace: biological_process +def: "The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-4 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032634 +name: interleukin-5 production +namespace: biological_process +def: "The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-5 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032635 +name: interleukin-6 production +namespace: biological_process +def: "The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-6 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032636 +name: interleukin-7 production +namespace: biological_process +def: "The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-7 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032637 +name: interleukin-8 production +namespace: biological_process +def: "The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-8 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032638 +name: interleukin-9 production +namespace: biological_process +def: "The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-9 production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0032639 +name: TRAIL production +namespace: biological_process +def: "The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +is_a: GO:0071706 ! tumor necrosis factor superfamily cytokine production + +[Term] +id: GO:0032640 +name: tumor necrosis factor production +namespace: biological_process +def: "The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "TNF production" EXACT [] +synonym: "TNF-alpha production" EXACT [] +synonym: "tumor necrosis factor-alpha production" EXACT [] +is_a: GO:0071706 ! tumor necrosis factor superfamily cytokine production + +[Term] +id: GO:0032641 +name: lymphotoxin A production +namespace: biological_process +def: "The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "LTA production" EXACT [] +synonym: "lymphotoxin-alpha production" EXACT [] +synonym: "TNF-beta production" EXACT [] +synonym: "tumor necrosis factor-beta production" EXACT [] +is_a: GO:0071706 ! tumor necrosis factor superfamily cytokine production + +[Term] +id: GO:0032642 +name: regulation of chemokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of chemokine production." [GOC:mah] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032602 ! chemokine production +relationship: regulates GO:0032602 ! chemokine production + +[Term] +id: GO:0032643 +name: regulation of connective tissue growth factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah] +synonym: "regulation of CCN2 production" EXACT [] +synonym: "regulation of CTGF production" EXACT [] +synonym: "regulation of Fisp12 production" EXACT [] +synonym: "regulation of Hcs24 production" EXACT [] +synonym: "regulation of hypertrophic chondrocyte-specific gene product 24 production" EXACT [] +synonym: "regulation of IGFBP8 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032601 ! connective tissue growth factor production +relationship: regulates GO:0032601 ! connective tissue growth factor production + +[Term] +id: GO:0032644 +name: regulation of fractalkine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of fractalkine production." [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032603 ! fractalkine production +relationship: regulates GO:0032603 ! fractalkine production + +[Term] +id: GO:0032645 +name: regulation of granulocyte macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah] +synonym: "regulation of GM-CSF production" EXACT [GOC:vk] +synonym: "regulation of granulocyte macrophage colony stimulating factor production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production +relationship: regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production + +[Term] +id: GO:0032646 +name: regulation of hepatocyte growth factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032605 ! hepatocyte growth factor production +relationship: regulates GO:0032605 ! hepatocyte growth factor production + +[Term] +id: GO:0032647 +name: regulation of interferon-alpha production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interferon-alpha production." [GOC:mah] +is_a: GO:0032479 ! regulation of type I interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032607 ! interferon-alpha production +relationship: regulates GO:0032607 ! interferon-alpha production + +[Term] +id: GO:0032648 +name: regulation of interferon-beta production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interferon-beta production." [GOC:mah] +synonym: "regulation of IFN-beta production" EXACT [] +is_a: GO:0032479 ! regulation of type I interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032608 ! interferon-beta production +relationship: regulates GO:0032608 ! interferon-beta production + +[Term] +id: GO:0032649 +name: regulation of interferon-gamma production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah] +synonym: "regulation of type II interferon production" BROAD [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032609 ! interferon-gamma production +relationship: regulates GO:0032609 ! interferon-gamma production + +[Term] +id: GO:0032650 +name: regulation of interleukin-1 alpha production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah] +synonym: "regulation of IL-1 alpha production" EXACT [] +is_a: GO:0032652 ! regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032610 ! interleukin-1 alpha production +relationship: regulates GO:0032610 ! interleukin-1 alpha production + +[Term] +id: GO:0032651 +name: regulation of interleukin-1 beta production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah] +synonym: "regulation of IL-1 beta production" EXACT [] +is_a: GO:0032652 ! regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032611 ! interleukin-1 beta production +relationship: regulates GO:0032611 ! interleukin-1 beta production + +[Term] +id: GO:0032652 +name: regulation of interleukin-1 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-1 production." [GOC:mah] +synonym: "regulation of IL-1 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032612 ! interleukin-1 production +relationship: regulates GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0032653 +name: regulation of interleukin-10 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-10 production." [GOC:mah] +synonym: "regulation of IL-10 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032613 ! interleukin-10 production +relationship: regulates GO:0032613 ! interleukin-10 production + +[Term] +id: GO:0032654 +name: regulation of interleukin-11 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-11 production." [GOC:mah] +synonym: "regulation of IL-11 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032614 ! interleukin-11 production +relationship: regulates GO:0032614 ! interleukin-11 production + +[Term] +id: GO:0032655 +name: regulation of interleukin-12 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-12 production." [GOC:mah] +synonym: "regulation of IL-12 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032615 ! interleukin-12 production +relationship: regulates GO:0032615 ! interleukin-12 production + +[Term] +id: GO:0032656 +name: regulation of interleukin-13 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-13 production." [GOC:mah] +synonym: "regulation of IL-13 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032616 ! interleukin-13 production +relationship: regulates GO:0032616 ! interleukin-13 production + +[Term] +id: GO:0032657 +name: regulation of interleukin-14 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-14 production." [GOC:mah] +synonym: "regulation of IL-14 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032617 ! interleukin-14 production +relationship: regulates GO:0032617 ! interleukin-14 production + +[Term] +id: GO:0032658 +name: regulation of interleukin-15 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-15 production." [GOC:mah] +synonym: "regulation of IL-15 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032618 ! interleukin-15 production +relationship: regulates GO:0032618 ! interleukin-15 production + +[Term] +id: GO:0032659 +name: regulation of interleukin-16 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-16 production." [GOC:mah] +synonym: "regulation of IL-16 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032619 ! interleukin-16 production +relationship: regulates GO:0032619 ! interleukin-16 production + +[Term] +id: GO:0032660 +name: regulation of interleukin-17 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah] +synonym: "regulation of IL-17 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032620 ! interleukin-17 production +relationship: regulates GO:0032620 ! interleukin-17 production + +[Term] +id: GO:0032661 +name: regulation of interleukin-18 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-18 production." [GOC:mah] +synonym: "regulation of IL-18 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032621 ! interleukin-18 production +relationship: regulates GO:0032621 ! interleukin-18 production + +[Term] +id: GO:0032662 +name: regulation of interleukin-19 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-19 production." [GOC:mah] +synonym: "regulation of IL-19 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032622 ! interleukin-19 production +relationship: regulates GO:0032622 ! interleukin-19 production + +[Term] +id: GO:0032663 +name: regulation of interleukin-2 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-2 production." [GOC:mah] +synonym: "regulation of IL-2 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032623 ! interleukin-2 production +relationship: regulates GO:0032623 ! interleukin-2 production + +[Term] +id: GO:0032664 +name: regulation of interleukin-20 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-20 production." [GOC:mah] +synonym: "regulation of IL-20 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032624 ! interleukin-20 production +relationship: regulates GO:0032624 ! interleukin-20 production + +[Term] +id: GO:0032665 +name: regulation of interleukin-21 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-21 production." [GOC:mah] +synonym: "regulation of IL-21 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032625 ! interleukin-21 production +relationship: regulates GO:0032625 ! interleukin-21 production + +[Term] +id: GO:0032666 +name: regulation of interleukin-22 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-22 production." [GOC:mah] +synonym: "regulation of IL-22 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032626 ! interleukin-22 production +relationship: regulates GO:0032626 ! interleukin-22 production + +[Term] +id: GO:0032667 +name: regulation of interleukin-23 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-23 production." [GOC:mah] +synonym: "regulation of IL-23 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032627 ! interleukin-23 production +relationship: regulates GO:0032627 ! interleukin-23 production + +[Term] +id: GO:0032668 +name: regulation of interleukin-24 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-24 production." [GOC:mah] +synonym: "regulation of IL-24 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032628 ! interleukin-24 production +relationship: regulates GO:0032628 ! interleukin-24 production + +[Term] +id: GO:0032669 +name: regulation of interleukin-25 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-25 production." [GOC:mah] +synonym: "regulation of IL-25 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032629 ! interleukin-25 production +relationship: regulates GO:0032629 ! interleukin-25 production + +[Term] +id: GO:0032670 +name: regulation of interleukin-26 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-26 production." [GOC:mah] +synonym: "regulation of IL-26 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032630 ! interleukin-26 production +relationship: regulates GO:0032630 ! interleukin-26 production + +[Term] +id: GO:0032671 +name: regulation of interleukin-27 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-27 production." [GOC:mah] +synonym: "regulation of IL-27 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032631 ! interleukin-27 production +relationship: regulates GO:0032631 ! interleukin-27 production + +[Term] +id: GO:0032672 +name: regulation of interleukin-3 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-3 production." [GOC:mah] +synonym: "regulation of IL-3 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032632 ! interleukin-3 production +relationship: regulates GO:0032632 ! interleukin-3 production + +[Term] +id: GO:0032673 +name: regulation of interleukin-4 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-4 production." [GOC:mah] +synonym: "regulation of IL-4 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032633 ! interleukin-4 production +relationship: regulates GO:0032633 ! interleukin-4 production + +[Term] +id: GO:0032674 +name: regulation of interleukin-5 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-5 production." [GOC:mah] +synonym: "regulation of IL-5 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032634 ! interleukin-5 production +relationship: regulates GO:0032634 ! interleukin-5 production + +[Term] +id: GO:0032675 +name: regulation of interleukin-6 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-6 production." [GOC:mah] +synonym: "regulation of IL-6 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032635 ! interleukin-6 production +relationship: regulates GO:0032635 ! interleukin-6 production + +[Term] +id: GO:0032676 +name: regulation of interleukin-7 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-7 production." [GOC:mah] +synonym: "regulation of IL-7 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032636 ! interleukin-7 production +relationship: regulates GO:0032636 ! interleukin-7 production + +[Term] +id: GO:0032677 +name: regulation of interleukin-8 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-8 production." [GOC:mah] +synonym: "regulation of IL-8 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032637 ! interleukin-8 production +relationship: regulates GO:0032637 ! interleukin-8 production + +[Term] +id: GO:0032678 +name: regulation of interleukin-9 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-9 production." [GOC:mah] +synonym: "regulation of IL-9 production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032638 ! interleukin-9 production +relationship: regulates GO:0032638 ! interleukin-9 production + +[Term] +id: GO:0032679 +name: regulation of TRAIL production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of TRAIL production." [GOC:mah] +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032639 ! TRAIL production +relationship: regulates GO:0032639 ! TRAIL production + +[Term] +id: GO:0032680 +name: regulation of tumor necrosis factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "regulation of TNF production" EXACT [] +synonym: "regulation of TNF-alpha production" EXACT [] +synonym: "regulation of tumor necrosis factor-alpha production" EXACT [] +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032640 ! tumor necrosis factor production +relationship: regulates GO:0032640 ! tumor necrosis factor production + +[Term] +id: GO:0032681 +name: regulation of lymphotoxin A production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of lymphotoxin A production." [GOC:mah] +synonym: "regulation of LTA production" EXACT [] +synonym: "regulation of lymphotoxin-alpha production" EXACT [] +synonym: "regulation of TNF-beta production" EXACT [] +synonym: "regulation of tumor necrosis factor-beta production" EXACT [] +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032641 ! lymphotoxin A production +relationship: regulates GO:0032641 ! lymphotoxin A production + +[Term] +id: GO:0032682 +name: negative regulation of chemokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production." [GOC:mah] +synonym: "down regulation of chemokine production" EXACT [] +synonym: "down-regulation of chemokine production" EXACT [] +synonym: "downregulation of chemokine production" EXACT [] +synonym: "inhibition of chemokine production" NARROW [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032602 ! chemokine production +relationship: negatively_regulates GO:0032602 ! chemokine production + +[Term] +id: GO:0032683 +name: negative regulation of connective tissue growth factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah] +synonym: "down regulation of connective tissue growth factor production" EXACT [] +synonym: "down-regulation of connective tissue growth factor production" EXACT [] +synonym: "downregulation of connective tissue growth factor production" EXACT [] +synonym: "inhibition of connective tissue growth factor production" NARROW [] +synonym: "negative regulation of CCN2 production" EXACT [] +synonym: "negative regulation of CTGF production" EXACT [] +synonym: "negative regulation of Fisp12 production" EXACT [] +synonym: "negative regulation of Hcs24 production" EXACT [] +synonym: "negative regulation of hypertrophic chondrocyte-specific gene product 24 production" EXACT [] +synonym: "negative regulation of IGFBP8 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032643 ! regulation of connective tissue growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032601 ! connective tissue growth factor production +relationship: negatively_regulates GO:0032601 ! connective tissue growth factor production + +[Term] +id: GO:0032684 +name: negative regulation of fractalkine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production." [GOC:mah] +synonym: "down regulation of fractalkine production" EXACT [] +synonym: "down-regulation of fractalkine production" EXACT [] +synonym: "downregulation of fractalkine production" EXACT [] +synonym: "inhibition of fractalkine production" NARROW [] +is_a: GO:0032644 ! regulation of fractalkine production +is_a: GO:0032682 ! negative regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032603 ! fractalkine production +relationship: negatively_regulates GO:0032603 ! fractalkine production + +[Term] +id: GO:0032685 +name: negative regulation of granulocyte macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah] +synonym: "down regulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +synonym: "down-regulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +synonym: "downregulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +synonym: "inhibition of granulocyte macrophage colony-stimulating factor production" NARROW [] +synonym: "negative regulation of GM-CSF production" EXACT [GOC:vk] +synonym: "negative regulation of granulocyte macrophage colony stimulating factor production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032645 ! regulation of granulocyte macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production +relationship: negatively_regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production + +[Term] +id: GO:0032686 +name: negative regulation of hepatocyte growth factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah] +synonym: "down regulation of hepatocyte growth factor production" EXACT [] +synonym: "down-regulation of hepatocyte growth factor production" EXACT [] +synonym: "downregulation of hepatocyte growth factor production" EXACT [] +synonym: "inhibition of hepatocyte growth factor production" NARROW [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032646 ! regulation of hepatocyte growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032605 ! hepatocyte growth factor production +relationship: negatively_regulates GO:0032605 ! hepatocyte growth factor production + +[Term] +id: GO:0032687 +name: negative regulation of interferon-alpha production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production." [GOC:mah] +synonym: "down regulation of interferon-alpha production" EXACT [] +synonym: "down-regulation of interferon-alpha production" EXACT [] +synonym: "downregulation of interferon-alpha production" EXACT [] +synonym: "inhibition of interferon-alpha production" NARROW [] +is_a: GO:0032480 ! negative regulation of type I interferon production +is_a: GO:0032647 ! regulation of interferon-alpha production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032607 ! interferon-alpha production +relationship: negatively_regulates GO:0032607 ! interferon-alpha production + +[Term] +id: GO:0032688 +name: negative regulation of interferon-beta production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production." [GOC:mah] +synonym: "down regulation of interferon-beta production" EXACT [] +synonym: "down-regulation of interferon-beta production" EXACT [] +synonym: "downregulation of interferon-beta production" EXACT [] +synonym: "inhibition of interferon-beta production" NARROW [] +synonym: "negative regulation of IFN-beta production" EXACT [] +is_a: GO:0032480 ! negative regulation of type I interferon production +is_a: GO:0032648 ! regulation of interferon-beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032608 ! interferon-beta production +relationship: negatively_regulates GO:0032608 ! interferon-beta production + +[Term] +id: GO:0032689 +name: negative regulation of interferon-gamma production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah] +synonym: "down regulation of interferon-gamma production" EXACT [] +synonym: "down-regulation of interferon-gamma production" EXACT [] +synonym: "downregulation of interferon-gamma production" EXACT [] +synonym: "inhibition of interferon-gamma production" NARROW [] +synonym: "negative regulation of type II interferon production" BROAD [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032649 ! regulation of interferon-gamma production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032609 ! interferon-gamma production +relationship: negatively_regulates GO:0032609 ! interferon-gamma production + +[Term] +id: GO:0032690 +name: negative regulation of interleukin-1 alpha production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah] +synonym: "down regulation of interleukin-1 alpha production" EXACT [] +synonym: "down-regulation of interleukin-1 alpha production" EXACT [] +synonym: "downregulation of interleukin-1 alpha production" EXACT [] +synonym: "inhibition of interleukin-1 alpha production" NARROW [] +synonym: "negative regulation of IL-1 alpha production" EXACT [] +is_a: GO:0032650 ! regulation of interleukin-1 alpha production +is_a: GO:0032692 ! negative regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032610 ! interleukin-1 alpha production +relationship: negatively_regulates GO:0032610 ! interleukin-1 alpha production + +[Term] +id: GO:0032691 +name: negative regulation of interleukin-1 beta production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah] +synonym: "down regulation of interleukin-1 beta production" EXACT [] +synonym: "down-regulation of interleukin-1 beta production" EXACT [] +synonym: "downregulation of interleukin-1 beta production" EXACT [] +synonym: "inhibition of interleukin-1 beta production" NARROW [] +synonym: "negative regulation of IL-1 beta production" EXACT [] +is_a: GO:0032651 ! regulation of interleukin-1 beta production +is_a: GO:0032692 ! negative regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032611 ! interleukin-1 beta production +relationship: negatively_regulates GO:0032611 ! interleukin-1 beta production + +[Term] +id: GO:0032692 +name: negative regulation of interleukin-1 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production." [GOC:mah] +synonym: "down regulation of interleukin-1 production" EXACT [] +synonym: "down-regulation of interleukin-1 production" EXACT [] +synonym: "downregulation of interleukin-1 production" EXACT [] +synonym: "inhibition of interleukin-1 production" NARROW [] +synonym: "negative regulation of IL-1 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032652 ! regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032612 ! interleukin-1 production +relationship: negatively_regulates GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0032693 +name: negative regulation of interleukin-10 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production." [GOC:mah] +synonym: "down regulation of interleukin-10 production" EXACT [] +synonym: "down-regulation of interleukin-10 production" EXACT [] +synonym: "downregulation of interleukin-10 production" EXACT [] +synonym: "inhibition of interleukin-10 production" NARROW [] +synonym: "negative regulation of IL-10 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032653 ! regulation of interleukin-10 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032613 ! interleukin-10 production +relationship: negatively_regulates GO:0032613 ! interleukin-10 production + +[Term] +id: GO:0032694 +name: negative regulation of interleukin-11 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production." [GOC:mah] +synonym: "down regulation of interleukin-11 production" EXACT [] +synonym: "down-regulation of interleukin-11 production" EXACT [] +synonym: "downregulation of interleukin-11 production" EXACT [] +synonym: "inhibition of interleukin-11 production" NARROW [] +synonym: "negative regulation of IL-11 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032654 ! regulation of interleukin-11 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032614 ! interleukin-11 production +relationship: negatively_regulates GO:0032614 ! interleukin-11 production + +[Term] +id: GO:0032695 +name: negative regulation of interleukin-12 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production." [GOC:mah] +synonym: "down regulation of interleukin-12 production" EXACT [] +synonym: "down-regulation of interleukin-12 production" EXACT [] +synonym: "downregulation of interleukin-12 production" EXACT [] +synonym: "inhibition of interleukin-12 production" NARROW [] +synonym: "negative regulation of IL-12 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032655 ! regulation of interleukin-12 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032615 ! interleukin-12 production +relationship: negatively_regulates GO:0032615 ! interleukin-12 production + +[Term] +id: GO:0032696 +name: negative regulation of interleukin-13 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production." [GOC:mah] +synonym: "down regulation of interleukin-13 production" EXACT [] +synonym: "down-regulation of interleukin-13 production" EXACT [] +synonym: "downregulation of interleukin-13 production" EXACT [] +synonym: "inhibition of interleukin-13 production" NARROW [] +synonym: "negative regulation of IL-13 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032656 ! regulation of interleukin-13 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032616 ! interleukin-13 production +relationship: negatively_regulates GO:0032616 ! interleukin-13 production + +[Term] +id: GO:0032697 +name: negative regulation of interleukin-14 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production." [GOC:mah] +synonym: "down regulation of interleukin-14 production" EXACT [] +synonym: "down-regulation of interleukin-14 production" EXACT [] +synonym: "downregulation of interleukin-14 production" EXACT [] +synonym: "inhibition of interleukin-14 production" NARROW [] +synonym: "negative regulation of IL-14 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032657 ! regulation of interleukin-14 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032617 ! interleukin-14 production +relationship: negatively_regulates GO:0032617 ! interleukin-14 production + +[Term] +id: GO:0032698 +name: negative regulation of interleukin-15 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production." [GOC:mah] +synonym: "down regulation of interleukin-15 production" EXACT [] +synonym: "down-regulation of interleukin-15 production" EXACT [] +synonym: "downregulation of interleukin-15 production" EXACT [] +synonym: "inhibition of interleukin-15 production" NARROW [] +synonym: "negative regulation of IL-15 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032658 ! regulation of interleukin-15 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032618 ! interleukin-15 production +relationship: negatively_regulates GO:0032618 ! interleukin-15 production + +[Term] +id: GO:0032699 +name: negative regulation of interleukin-16 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production." [GOC:mah] +synonym: "down regulation of interleukin-16 production" EXACT [] +synonym: "down-regulation of interleukin-16 production" EXACT [] +synonym: "downregulation of interleukin-16 production" EXACT [] +synonym: "inhibition of interleukin-16 production" NARROW [] +synonym: "negative regulation of IL-16 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032659 ! regulation of interleukin-16 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032619 ! interleukin-16 production +relationship: negatively_regulates GO:0032619 ! interleukin-16 production + +[Term] +id: GO:0032700 +name: negative regulation of interleukin-17 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah] +synonym: "down regulation of interleukin-17 production" EXACT [] +synonym: "down-regulation of interleukin-17 production" EXACT [] +synonym: "downregulation of interleukin-17 production" EXACT [] +synonym: "inhibition of interleukin-17 production" NARROW [] +synonym: "negative regulation of IL-17 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032660 ! regulation of interleukin-17 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032620 ! interleukin-17 production +relationship: negatively_regulates GO:0032620 ! interleukin-17 production + +[Term] +id: GO:0032701 +name: negative regulation of interleukin-18 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production." [GOC:mah] +synonym: "down regulation of interleukin-18 production" EXACT [] +synonym: "down-regulation of interleukin-18 production" EXACT [] +synonym: "downregulation of interleukin-18 production" EXACT [] +synonym: "inhibition of interleukin-18 production" NARROW [] +synonym: "negative regulation of IL-18 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032661 ! regulation of interleukin-18 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032621 ! interleukin-18 production +relationship: negatively_regulates GO:0032621 ! interleukin-18 production + +[Term] +id: GO:0032702 +name: negative regulation of interleukin-19 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production." [GOC:mah] +synonym: "down regulation of interleukin-19 production" EXACT [] +synonym: "down-regulation of interleukin-19 production" EXACT [] +synonym: "downregulation of interleukin-19 production" EXACT [] +synonym: "inhibition of interleukin-19 production" NARROW [] +synonym: "negative regulation of IL-19 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032662 ! regulation of interleukin-19 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032622 ! interleukin-19 production +relationship: negatively_regulates GO:0032622 ! interleukin-19 production + +[Term] +id: GO:0032703 +name: negative regulation of interleukin-2 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production." [GOC:mah] +synonym: "down regulation of interleukin-2 production" EXACT [] +synonym: "down-regulation of interleukin-2 production" EXACT [] +synonym: "downregulation of interleukin-2 production" EXACT [] +synonym: "inhibition of interleukin-2 production" NARROW [] +synonym: "negative regulation of IL-2 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032663 ! regulation of interleukin-2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032623 ! interleukin-2 production +relationship: negatively_regulates GO:0032623 ! interleukin-2 production + +[Term] +id: GO:0032704 +name: negative regulation of interleukin-20 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production." [GOC:mah] +synonym: "down regulation of interleukin-20 production" EXACT [] +synonym: "down-regulation of interleukin-20 production" EXACT [] +synonym: "downregulation of interleukin-20 production" EXACT [] +synonym: "inhibition of interleukin-20 production" NARROW [] +synonym: "negative regulation of IL-20 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032664 ! regulation of interleukin-20 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032624 ! interleukin-20 production +relationship: negatively_regulates GO:0032624 ! interleukin-20 production + +[Term] +id: GO:0032705 +name: negative regulation of interleukin-21 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production." [GOC:mah] +synonym: "down regulation of interleukin-21 production" EXACT [] +synonym: "down-regulation of interleukin-21 production" EXACT [] +synonym: "downregulation of interleukin-21 production" EXACT [] +synonym: "inhibition of interleukin-21 production" NARROW [] +synonym: "negative regulation of IL-21 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032665 ! regulation of interleukin-21 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032625 ! interleukin-21 production +relationship: negatively_regulates GO:0032625 ! interleukin-21 production + +[Term] +id: GO:0032706 +name: negative regulation of interleukin-22 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production." [GOC:mah] +synonym: "down regulation of interleukin-22 production" EXACT [] +synonym: "down-regulation of interleukin-22 production" EXACT [] +synonym: "downregulation of interleukin-22 production" EXACT [] +synonym: "inhibition of interleukin-22 production" NARROW [] +synonym: "negative regulation of IL-22 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032666 ! regulation of interleukin-22 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032626 ! interleukin-22 production +relationship: negatively_regulates GO:0032626 ! interleukin-22 production + +[Term] +id: GO:0032707 +name: negative regulation of interleukin-23 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production." [GOC:mah] +synonym: "down regulation of interleukin-23 production" EXACT [] +synonym: "down-regulation of interleukin-23 production" EXACT [] +synonym: "downregulation of interleukin-23 production" EXACT [] +synonym: "inhibition of interleukin-23 production" NARROW [] +synonym: "negative regulation of IL-23 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032667 ! regulation of interleukin-23 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032627 ! interleukin-23 production +relationship: negatively_regulates GO:0032627 ! interleukin-23 production + +[Term] +id: GO:0032708 +name: negative regulation of interleukin-24 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production." [GOC:mah] +synonym: "down regulation of interleukin-24 production" EXACT [] +synonym: "down-regulation of interleukin-24 production" EXACT [] +synonym: "downregulation of interleukin-24 production" EXACT [] +synonym: "inhibition of interleukin-24 production" NARROW [] +synonym: "negative regulation of IL-24 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032668 ! regulation of interleukin-24 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032628 ! interleukin-24 production +relationship: negatively_regulates GO:0032628 ! interleukin-24 production + +[Term] +id: GO:0032709 +name: negative regulation of interleukin-25 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production." [GOC:mah] +synonym: "down regulation of interleukin-25 production" EXACT [] +synonym: "down-regulation of interleukin-25 production" EXACT [] +synonym: "downregulation of interleukin-25 production" EXACT [] +synonym: "inhibition of interleukin-25 production" NARROW [] +synonym: "negative regulation of IL-25 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032669 ! regulation of interleukin-25 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032629 ! interleukin-25 production +relationship: negatively_regulates GO:0032629 ! interleukin-25 production + +[Term] +id: GO:0032710 +name: negative regulation of interleukin-26 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production." [GOC:mah] +synonym: "down regulation of interleukin-26 production" EXACT [] +synonym: "down-regulation of interleukin-26 production" EXACT [] +synonym: "downregulation of interleukin-26 production" EXACT [] +synonym: "inhibition of interleukin-26 production" NARROW [] +synonym: "negative regulation of IL-26 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032670 ! regulation of interleukin-26 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032630 ! interleukin-26 production +relationship: negatively_regulates GO:0032630 ! interleukin-26 production + +[Term] +id: GO:0032711 +name: negative regulation of interleukin-27 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production." [GOC:mah] +synonym: "down regulation of interleukin-27 production" EXACT [] +synonym: "down-regulation of interleukin-27 production" EXACT [] +synonym: "downregulation of interleukin-27 production" EXACT [] +synonym: "inhibition of interleukin-27 production" NARROW [] +synonym: "negative regulation of IL-27 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032671 ! regulation of interleukin-27 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032631 ! interleukin-27 production +relationship: negatively_regulates GO:0032631 ! interleukin-27 production + +[Term] +id: GO:0032712 +name: negative regulation of interleukin-3 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production." [GOC:mah] +synonym: "down regulation of interleukin-3 production" EXACT [] +synonym: "down-regulation of interleukin-3 production" EXACT [] +synonym: "downregulation of interleukin-3 production" EXACT [] +synonym: "inhibition of interleukin-3 production" NARROW [] +synonym: "negative regulation of IL-3 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032672 ! regulation of interleukin-3 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032632 ! interleukin-3 production +relationship: negatively_regulates GO:0032632 ! interleukin-3 production + +[Term] +id: GO:0032713 +name: negative regulation of interleukin-4 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production." [GOC:mah] +synonym: "down regulation of interleukin-4 production" EXACT [] +synonym: "down-regulation of interleukin-4 production" EXACT [] +synonym: "downregulation of interleukin-4 production" EXACT [] +synonym: "inhibition of interleukin-4 production" NARROW [] +synonym: "negative regulation of IL-4 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032673 ! regulation of interleukin-4 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032633 ! interleukin-4 production +relationship: negatively_regulates GO:0032633 ! interleukin-4 production + +[Term] +id: GO:0032714 +name: negative regulation of interleukin-5 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production." [GOC:mah] +synonym: "down regulation of interleukin-5 production" EXACT [] +synonym: "down-regulation of interleukin-5 production" EXACT [] +synonym: "downregulation of interleukin-5 production" EXACT [] +synonym: "inhibition of interleukin-5 production" NARROW [] +synonym: "negative regulation of IL-5 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032674 ! regulation of interleukin-5 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032634 ! interleukin-5 production +relationship: negatively_regulates GO:0032634 ! interleukin-5 production + +[Term] +id: GO:0032715 +name: negative regulation of interleukin-6 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production." [GOC:mah] +synonym: "down regulation of interleukin-6 production" EXACT [] +synonym: "down-regulation of interleukin-6 production" EXACT [] +synonym: "downregulation of interleukin-6 production" EXACT [] +synonym: "inhibition of interleukin-6 production" NARROW [] +synonym: "negative regulation of IL-6 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032675 ! regulation of interleukin-6 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032635 ! interleukin-6 production +relationship: negatively_regulates GO:0032635 ! interleukin-6 production + +[Term] +id: GO:0032716 +name: negative regulation of interleukin-7 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production." [GOC:mah] +synonym: "down regulation of interleukin-7 production" EXACT [] +synonym: "down-regulation of interleukin-7 production" EXACT [] +synonym: "downregulation of interleukin-7 production" EXACT [] +synonym: "inhibition of interleukin-7 production" NARROW [] +synonym: "negative regulation of IL-7 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032676 ! regulation of interleukin-7 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032636 ! interleukin-7 production +relationship: negatively_regulates GO:0032636 ! interleukin-7 production + +[Term] +id: GO:0032717 +name: negative regulation of interleukin-8 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production." [GOC:mah] +synonym: "down regulation of interleukin-8 production" EXACT [] +synonym: "down-regulation of interleukin-8 production" EXACT [] +synonym: "downregulation of interleukin-8 production" EXACT [] +synonym: "inhibition of interleukin-8 production" NARROW [] +synonym: "negative regulation of IL-8 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032677 ! regulation of interleukin-8 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032637 ! interleukin-8 production +relationship: negatively_regulates GO:0032637 ! interleukin-8 production + +[Term] +id: GO:0032718 +name: negative regulation of interleukin-9 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production." [GOC:mah] +synonym: "down regulation of interleukin-9 production" EXACT [] +synonym: "down-regulation of interleukin-9 production" EXACT [] +synonym: "downregulation of interleukin-9 production" EXACT [] +synonym: "inhibition of interleukin-9 production" NARROW [] +synonym: "negative regulation of IL-9 production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0032678 ! regulation of interleukin-9 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032638 ! interleukin-9 production +relationship: negatively_regulates GO:0032638 ! interleukin-9 production + +[Term] +id: GO:0032719 +name: negative regulation of TRAIL production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production." [GOC:mah] +synonym: "down regulation of TRAIL production" EXACT [] +synonym: "down-regulation of TRAIL production" EXACT [] +synonym: "downregulation of TRAIL production" EXACT [] +synonym: "inhibition of TRAIL production" NARROW [] +is_a: GO:0032679 ! regulation of TRAIL production +is_a: GO:1903556 ! negative regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032639 ! TRAIL production +relationship: negatively_regulates GO:0032639 ! TRAIL production + +[Term] +id: GO:0032720 +name: negative regulation of tumor necrosis factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "down regulation of tumor necrosis factor production" EXACT [] +synonym: "down-regulation of tumor necrosis factor production" EXACT [] +synonym: "downregulation of tumor necrosis factor production" EXACT [] +synonym: "inhibition of tumor necrosis factor production" NARROW [] +synonym: "negative regulation TNF production" EXACT [] +synonym: "negative regulation TNF-alpha production" EXACT [] +synonym: "negative regulation tumor necrosis factor-alpha production" EXACT [] +is_a: GO:0032680 ! regulation of tumor necrosis factor production +is_a: GO:1903556 ! negative regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032640 ! tumor necrosis factor production +relationship: negatively_regulates GO:0032640 ! tumor necrosis factor production + +[Term] +id: GO:0032721 +name: negative regulation of lymphotoxin A production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production." [GOC:mah] +synonym: "down regulation of lymphotoxin A production" EXACT [] +synonym: "down-regulation of lymphotoxin A production" EXACT [] +synonym: "downregulation of lymphotoxin A production" EXACT [] +synonym: "inhibition of lymphotoxin A production" NARROW [] +synonym: "negative regulation of LTA production" EXACT [] +synonym: "negative regulation of lymphotoxin-alpha production" EXACT [] +synonym: "negative regulation of TNF-beta production" EXACT [] +synonym: "negative regulation of tumor necrosis factor-beta production" EXACT [] +is_a: GO:0032681 ! regulation of lymphotoxin A production +is_a: GO:1903556 ! negative regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032641 ! lymphotoxin A production +relationship: negatively_regulates GO:0032641 ! lymphotoxin A production + +[Term] +id: GO:0032722 +name: positive regulation of chemokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of chemokine production." [GOC:mah] +synonym: "activation of chemokine production" NARROW [] +synonym: "stimulation of chemokine production" NARROW [] +synonym: "up regulation of chemokine production" EXACT [] +synonym: "up-regulation of chemokine production" EXACT [] +synonym: "upregulation of chemokine production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032602 ! chemokine production +relationship: positively_regulates GO:0032602 ! chemokine production + +[Term] +id: GO:0032723 +name: positive regulation of connective tissue growth factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production." [GOC:mah] +synonym: "activation of connective tissue growth factor production" NARROW [] +synonym: "positive regulation of CCN2 production" EXACT [] +synonym: "positive regulation of CTGF production" EXACT [] +synonym: "positive regulation of Fisp12 production" EXACT [] +synonym: "positive regulation of Hcs24 production" EXACT [] +synonym: "positive regulation of hypertrophic chondrocyte-specific gene product 24 production" EXACT [] +synonym: "positive regulation of IGFBP8 production" EXACT [] +synonym: "stimulation of connective tissue growth factor production" NARROW [] +synonym: "up regulation of connective tissue growth factor production" EXACT [] +synonym: "up-regulation of connective tissue growth factor production" EXACT [] +synonym: "upregulation of connective tissue growth factor production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032643 ! regulation of connective tissue growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032601 ! connective tissue growth factor production +relationship: positively_regulates GO:0032601 ! connective tissue growth factor production + +[Term] +id: GO:0032724 +name: positive regulation of fractalkine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of fractalkine production." [GOC:mah] +synonym: "activation of fractalkine production" NARROW [] +synonym: "stimulation of fractalkine production" NARROW [] +synonym: "up regulation of fractalkine production" EXACT [] +synonym: "up-regulation of fractalkine production" EXACT [] +synonym: "upregulation of fractalkine production" EXACT [] +is_a: GO:0032644 ! regulation of fractalkine production +is_a: GO:0032722 ! positive regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032603 ! fractalkine production +relationship: positively_regulates GO:0032603 ! fractalkine production + +[Term] +id: GO:0032725 +name: positive regulation of granulocyte macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production." [GOC:mah] +synonym: "activation of granulocyte macrophage colony-stimulating factor production" NARROW [] +synonym: "positive regulation of GM-CSF production" EXACT [GOC:vk] +synonym: "positive regulation of granulocyte macrophage colony stimulating factor production" EXACT [] +synonym: "stimulation of granulocyte macrophage colony-stimulating factor production" NARROW [] +synonym: "up regulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +synonym: "up-regulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +synonym: "upregulation of granulocyte macrophage colony-stimulating factor production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032645 ! regulation of granulocyte macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production +relationship: positively_regulates GO:0032604 ! granulocyte macrophage colony-stimulating factor production + +[Term] +id: GO:0032726 +name: positive regulation of hepatocyte growth factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production." [GOC:mah] +synonym: "activation of hepatocyte growth factor production" NARROW [] +synonym: "stimulation of hepatocyte growth factor production" NARROW [] +synonym: "up regulation of hepatocyte growth factor production" EXACT [] +synonym: "up-regulation of hepatocyte growth factor production" EXACT [] +synonym: "upregulation of hepatocyte growth factor production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032646 ! regulation of hepatocyte growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032605 ! hepatocyte growth factor production +relationship: positively_regulates GO:0032605 ! hepatocyte growth factor production + +[Term] +id: GO:0032727 +name: positive regulation of interferon-alpha production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interferon-alpha production." [GOC:mah] +synonym: "activation of interferon-alpha production" NARROW [] +synonym: "stimulation of interferon-alpha production" NARROW [] +synonym: "up regulation of interferon-alpha production" EXACT [] +synonym: "up-regulation of interferon-alpha production" EXACT [] +synonym: "upregulation of interferon-alpha production" EXACT [] +is_a: GO:0032481 ! positive regulation of type I interferon production +is_a: GO:0032647 ! regulation of interferon-alpha production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032607 ! interferon-alpha production +relationship: positively_regulates GO:0032607 ! interferon-alpha production + +[Term] +id: GO:0032728 +name: positive regulation of interferon-beta production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interferon-beta production." [GOC:mah] +synonym: "activation of interferon-beta production" NARROW [] +synonym: "positive regulation of IFN-beta production" EXACT [] +synonym: "stimulation of interferon-beta production" NARROW [] +synonym: "up regulation of interferon-beta production" EXACT [] +synonym: "up-regulation of interferon-beta production" EXACT [] +synonym: "upregulation of interferon-beta production" EXACT [] +is_a: GO:0032481 ! positive regulation of type I interferon production +is_a: GO:0032648 ! regulation of interferon-beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032608 ! interferon-beta production +relationship: positively_regulates GO:0032608 ! interferon-beta production + +[Term] +id: GO:0032729 +name: positive regulation of interferon-gamma production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:mah] +synonym: "activation of interferon-gamma production" NARROW [] +synonym: "positive regulation of type II interferon production" BROAD [] +synonym: "stimulation of interferon-gamma production" NARROW [] +synonym: "up regulation of interferon-gamma production" EXACT [] +synonym: "up-regulation of interferon-gamma production" EXACT [] +synonym: "upregulation of interferon-gamma production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032649 ! regulation of interferon-gamma production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032609 ! interferon-gamma production +relationship: positively_regulates GO:0032609 ! interferon-gamma production + +[Term] +id: GO:0032730 +name: positive regulation of interleukin-1 alpha production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production." [GOC:mah] +synonym: "activation of interleukin-1 alpha production" NARROW [] +synonym: "positive regulation of IL-1 alpha production" EXACT [] +synonym: "stimulation of interleukin-1 alpha production" NARROW [] +synonym: "up regulation of interleukin-1 alpha production" EXACT [] +synonym: "up-regulation of interleukin-1 alpha production" EXACT [] +synonym: "upregulation of interleukin-1 alpha production" EXACT [] +is_a: GO:0032650 ! regulation of interleukin-1 alpha production +is_a: GO:0032732 ! positive regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032610 ! interleukin-1 alpha production +relationship: positively_regulates GO:0032610 ! interleukin-1 alpha production + +[Term] +id: GO:0032731 +name: positive regulation of interleukin-1 beta production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production." [GOC:mah] +synonym: "activation of interleukin-1 beta production" NARROW [] +synonym: "positive regulation of IL-1 beta production" EXACT [] +synonym: "stimulation of interleukin-1 beta production" NARROW [] +synonym: "up regulation of interleukin-1 beta production" EXACT [] +synonym: "up-regulation of interleukin-1 beta production" EXACT [] +synonym: "upregulation of interleukin-1 beta production" EXACT [] +is_a: GO:0032651 ! regulation of interleukin-1 beta production +is_a: GO:0032732 ! positive regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032611 ! interleukin-1 beta production +relationship: positively_regulates GO:0032611 ! interleukin-1 beta production + +[Term] +id: GO:0032732 +name: positive regulation of interleukin-1 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-1 production." [GOC:mah] +synonym: "activation of interleukin-1 production" NARROW [] +synonym: "positive regulation of IL-1 production" EXACT [] +synonym: "stimulation of interleukin-1 production" NARROW [] +synonym: "up regulation of interleukin-1 production" EXACT [] +synonym: "up-regulation of interleukin-1 production" EXACT [] +synonym: "upregulation of interleukin-1 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032652 ! regulation of interleukin-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032612 ! interleukin-1 production +relationship: positively_regulates GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0032733 +name: positive regulation of interleukin-10 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-10 production." [GOC:mah] +synonym: "activation of interleukin-10 production" NARROW [] +synonym: "positive regulation of IL-10 production" EXACT [] +synonym: "stimulation of interleukin-10 production" NARROW [] +synonym: "up regulation of interleukin-10 production" EXACT [] +synonym: "up-regulation of interleukin-10 production" EXACT [] +synonym: "upregulation of interleukin-10 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032653 ! regulation of interleukin-10 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032613 ! interleukin-10 production +relationship: positively_regulates GO:0032613 ! interleukin-10 production + +[Term] +id: GO:0032734 +name: positive regulation of interleukin-11 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-11 production." [GOC:mah] +synonym: "activation of interleukin-11 production" NARROW [] +synonym: "positive regulation of IL-11 production" EXACT [] +synonym: "stimulation of interleukin-11 production" NARROW [] +synonym: "up regulation of interleukin-11 production" EXACT [] +synonym: "up-regulation of interleukin-11 production" EXACT [] +synonym: "upregulation of interleukin-11 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032654 ! regulation of interleukin-11 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032614 ! interleukin-11 production +relationship: positively_regulates GO:0032614 ! interleukin-11 production + +[Term] +id: GO:0032735 +name: positive regulation of interleukin-12 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-12 production." [GOC:mah] +synonym: "activation of interleukin-12 production" NARROW [] +synonym: "positive regulation of IL-12 production" EXACT [] +synonym: "stimulation of interleukin-12 production" NARROW [] +synonym: "up regulation of interleukin-12 production" EXACT [] +synonym: "up-regulation of interleukin-12 production" EXACT [] +synonym: "upregulation of interleukin-12 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032655 ! regulation of interleukin-12 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032615 ! interleukin-12 production +relationship: positively_regulates GO:0032615 ! interleukin-12 production + +[Term] +id: GO:0032736 +name: positive regulation of interleukin-13 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-13 production." [GOC:mah] +synonym: "activation of interleukin-13 production" NARROW [] +synonym: "positive regulation of IL-13 production" EXACT [] +synonym: "stimulation of interleukin-13 production" NARROW [] +synonym: "up regulation of interleukin-13 production" EXACT [] +synonym: "up-regulation of interleukin-13 production" EXACT [] +synonym: "upregulation of interleukin-13 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032656 ! regulation of interleukin-13 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032616 ! interleukin-13 production +relationship: positively_regulates GO:0032616 ! interleukin-13 production + +[Term] +id: GO:0032737 +name: positive regulation of interleukin-14 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-14 production." [GOC:mah] +synonym: "activation of interleukin-14 production" NARROW [] +synonym: "positive regulation of IL-14 production" EXACT [] +synonym: "stimulation of interleukin-14 production" NARROW [] +synonym: "up regulation of interleukin-14 production" EXACT [] +synonym: "up-regulation of interleukin-14 production" EXACT [] +synonym: "upregulation of interleukin-14 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032657 ! regulation of interleukin-14 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032617 ! interleukin-14 production +relationship: positively_regulates GO:0032617 ! interleukin-14 production + +[Term] +id: GO:0032738 +name: positive regulation of interleukin-15 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-15 production." [GOC:mah] +synonym: "activation of interleukin-15 production" NARROW [] +synonym: "positive regulation of IL-15 production" EXACT [] +synonym: "stimulation of interleukin-15 production" NARROW [] +synonym: "up regulation of interleukin-15 production" EXACT [] +synonym: "up-regulation of interleukin-15 production" EXACT [] +synonym: "upregulation of interleukin-15 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032658 ! regulation of interleukin-15 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032618 ! interleukin-15 production +relationship: positively_regulates GO:0032618 ! interleukin-15 production + +[Term] +id: GO:0032739 +name: positive regulation of interleukin-16 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-16 production." [GOC:mah] +synonym: "activation of interleukin-16 production" NARROW [] +synonym: "positive regulation of IL-16 production" EXACT [] +synonym: "stimulation of interleukin-16 production" NARROW [] +synonym: "up regulation of interleukin-16 production" EXACT [] +synonym: "up-regulation of interleukin-16 production" EXACT [] +synonym: "upregulation of interleukin-16 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032659 ! regulation of interleukin-16 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032619 ! interleukin-16 production +relationship: positively_regulates GO:0032619 ! interleukin-16 production + +[Term] +id: GO:0032740 +name: positive regulation of interleukin-17 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:mah] +synonym: "activation of interleukin-17 production" NARROW [] +synonym: "positive regulation of IL-17 production" EXACT [] +synonym: "stimulation of interleukin-17 production" NARROW [] +synonym: "up regulation of interleukin-17 production" EXACT [] +synonym: "up-regulation of interleukin-17 production" EXACT [] +synonym: "upregulation of interleukin-17 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032660 ! regulation of interleukin-17 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032620 ! interleukin-17 production +relationship: positively_regulates GO:0032620 ! interleukin-17 production + +[Term] +id: GO:0032741 +name: positive regulation of interleukin-18 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-18 production." [GOC:mah] +synonym: "activation of interleukin-18 production" NARROW [] +synonym: "positive regulation of IL-18 production" EXACT [] +synonym: "stimulation of interleukin-18 production" NARROW [] +synonym: "up regulation of interleukin-18 production" EXACT [] +synonym: "up-regulation of interleukin-18 production" EXACT [] +synonym: "upregulation of interleukin-18 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032661 ! regulation of interleukin-18 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032621 ! interleukin-18 production +relationship: positively_regulates GO:0032621 ! interleukin-18 production + +[Term] +id: GO:0032742 +name: positive regulation of interleukin-19 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-19 production." [GOC:mah] +synonym: "activation of interleukin-19 production" NARROW [] +synonym: "positive regulation of IL-19 production" EXACT [] +synonym: "stimulation of interleukin-19 production" NARROW [] +synonym: "up regulation of interleukin-19 production" EXACT [] +synonym: "up-regulation of interleukin-19 production" EXACT [] +synonym: "upregulation of interleukin-19 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032662 ! regulation of interleukin-19 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032622 ! interleukin-19 production +relationship: positively_regulates GO:0032622 ! interleukin-19 production + +[Term] +id: GO:0032743 +name: positive regulation of interleukin-2 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-2 production." [GOC:mah] +synonym: "activation of interleukin-2 production" NARROW [] +synonym: "positive regulation of IL-2 production" EXACT [] +synonym: "stimulation of interleukin-2 production" NARROW [] +synonym: "up regulation of interleukin-2 production" EXACT [] +synonym: "up-regulation of interleukin-2 production" EXACT [] +synonym: "upregulation of interleukin-2 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032663 ! regulation of interleukin-2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032623 ! interleukin-2 production +relationship: positively_regulates GO:0032623 ! interleukin-2 production + +[Term] +id: GO:0032744 +name: positive regulation of interleukin-20 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-20 production." [GOC:mah] +synonym: "activation of interleukin-20 production" NARROW [] +synonym: "positive regulation of IL-20 production" EXACT [] +synonym: "stimulation of interleukin-20 production" NARROW [] +synonym: "up regulation of interleukin-20 production" EXACT [] +synonym: "up-regulation of interleukin-20 production" EXACT [] +synonym: "upregulation of interleukin-20 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032664 ! regulation of interleukin-20 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032624 ! interleukin-20 production +relationship: positively_regulates GO:0032624 ! interleukin-20 production + +[Term] +id: GO:0032745 +name: positive regulation of interleukin-21 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-21 production." [GOC:mah] +synonym: "activation of interleukin-21 production" NARROW [] +synonym: "positive regulation of IL-21 production" EXACT [] +synonym: "stimulation of interleukin-21 production" NARROW [] +synonym: "up regulation of interleukin-21 production" EXACT [] +synonym: "up-regulation of interleukin-21 production" EXACT [] +synonym: "upregulation of interleukin-21 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032665 ! regulation of interleukin-21 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032625 ! interleukin-21 production +relationship: positively_regulates GO:0032625 ! interleukin-21 production + +[Term] +id: GO:0032746 +name: positive regulation of interleukin-22 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-22 production." [GOC:mah] +synonym: "activation of interleukin-22 production" NARROW [] +synonym: "positive regulation of IL-22 production" EXACT [] +synonym: "stimulation of interleukin-22 production" NARROW [] +synonym: "up regulation of interleukin-22 production" EXACT [] +synonym: "up-regulation of interleukin-22 production" EXACT [] +synonym: "upregulation of interleukin-22 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032666 ! regulation of interleukin-22 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032626 ! interleukin-22 production +relationship: positively_regulates GO:0032626 ! interleukin-22 production + +[Term] +id: GO:0032747 +name: positive regulation of interleukin-23 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-23 production." [GOC:mah] +synonym: "activation of interleukin-23 production" NARROW [] +synonym: "positive regulation of IL-23 production" EXACT [] +synonym: "stimulation of interleukin-23 production" NARROW [] +synonym: "up regulation of interleukin-23 production" EXACT [] +synonym: "up-regulation of interleukin-23 production" EXACT [] +synonym: "upregulation of interleukin-23 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032667 ! regulation of interleukin-23 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032627 ! interleukin-23 production +relationship: positively_regulates GO:0032627 ! interleukin-23 production + +[Term] +id: GO:0032748 +name: positive regulation of interleukin-24 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-24 production." [GOC:mah] +synonym: "activation of interleukin-24 production" NARROW [] +synonym: "positive regulation of IL-24 production" EXACT [] +synonym: "stimulation of interleukin-24 production" NARROW [] +synonym: "up regulation of interleukin-24 production" EXACT [] +synonym: "up-regulation of interleukin-24 production" EXACT [] +synonym: "upregulation of interleukin-24 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032668 ! regulation of interleukin-24 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032628 ! interleukin-24 production +relationship: positively_regulates GO:0032628 ! interleukin-24 production + +[Term] +id: GO:0032749 +name: positive regulation of interleukin-25 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-25 production." [GOC:mah] +synonym: "activation of interleukin-25 production" NARROW [] +synonym: "positive regulation of IL-25 production" EXACT [] +synonym: "stimulation of interleukin-25 production" NARROW [] +synonym: "up regulation of interleukin-25 production" EXACT [] +synonym: "up-regulation of interleukin-25 production" EXACT [] +synonym: "upregulation of interleukin-25 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032669 ! regulation of interleukin-25 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032629 ! interleukin-25 production +relationship: positively_regulates GO:0032629 ! interleukin-25 production + +[Term] +id: GO:0032750 +name: positive regulation of interleukin-26 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-26 production." [GOC:mah] +synonym: "activation of interleukin-26 production" NARROW [] +synonym: "positive regulation of IL-26 production" EXACT [] +synonym: "stimulation of interleukin-26 production" NARROW [] +synonym: "up regulation of interleukin-26 production" EXACT [] +synonym: "up-regulation of interleukin-26 production" EXACT [] +synonym: "upregulation of interleukin-26 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032670 ! regulation of interleukin-26 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032630 ! interleukin-26 production +relationship: positively_regulates GO:0032630 ! interleukin-26 production + +[Term] +id: GO:0032751 +name: positive regulation of interleukin-27 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-27 production." [GOC:mah] +synonym: "activation of interleukin-27 production" NARROW [] +synonym: "positive regulation of IL-27 production" EXACT [] +synonym: "stimulation of interleukin-27 production" NARROW [] +synonym: "up regulation of interleukin-27 production" EXACT [] +synonym: "up-regulation of interleukin-27 production" EXACT [] +synonym: "upregulation of interleukin-27 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032671 ! regulation of interleukin-27 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032631 ! interleukin-27 production +relationship: positively_regulates GO:0032631 ! interleukin-27 production + +[Term] +id: GO:0032752 +name: positive regulation of interleukin-3 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-3 production." [GOC:mah] +synonym: "activation of interleukin-3 production" NARROW [] +synonym: "positive regulation of IL-3 production" EXACT [] +synonym: "stimulation of interleukin-3 production" NARROW [] +synonym: "up regulation of interleukin-3 production" EXACT [] +synonym: "up-regulation of interleukin-3 production" EXACT [] +synonym: "upregulation of interleukin-3 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032672 ! regulation of interleukin-3 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032632 ! interleukin-3 production +relationship: positively_regulates GO:0032632 ! interleukin-3 production + +[Term] +id: GO:0032753 +name: positive regulation of interleukin-4 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-4 production." [GOC:mah] +synonym: "activation of interleukin-4 production" NARROW [] +synonym: "positive regulation of IL-4 production" EXACT [] +synonym: "stimulation of interleukin-4 production" NARROW [] +synonym: "up regulation of interleukin-4 production" EXACT [] +synonym: "up-regulation of interleukin-4 production" EXACT [] +synonym: "upregulation of interleukin-4 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032673 ! regulation of interleukin-4 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032633 ! interleukin-4 production +relationship: positively_regulates GO:0032633 ! interleukin-4 production + +[Term] +id: GO:0032754 +name: positive regulation of interleukin-5 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-5 production." [GOC:mah] +synonym: "activation of interleukin-5 production" NARROW [] +synonym: "positive regulation of IL-5 production" EXACT [] +synonym: "stimulation of interleukin-5 production" NARROW [] +synonym: "up regulation of interleukin-5 production" EXACT [] +synonym: "up-regulation of interleukin-5 production" EXACT [] +synonym: "upregulation of interleukin-5 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032674 ! regulation of interleukin-5 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032634 ! interleukin-5 production +relationship: positively_regulates GO:0032634 ! interleukin-5 production + +[Term] +id: GO:0032755 +name: positive regulation of interleukin-6 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-6 production." [GOC:mah] +synonym: "activation of interleukin-6 production" NARROW [] +synonym: "positive regulation of IL-6 production" EXACT [] +synonym: "stimulation of interleukin-6 production" NARROW [] +synonym: "up regulation of interleukin-6 production" EXACT [] +synonym: "up-regulation of interleukin-6 production" EXACT [] +synonym: "upregulation of interleukin-6 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032675 ! regulation of interleukin-6 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032635 ! interleukin-6 production +relationship: positively_regulates GO:0032635 ! interleukin-6 production + +[Term] +id: GO:0032756 +name: positive regulation of interleukin-7 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-7 production." [GOC:mah] +synonym: "activation of interleukin-7 production" NARROW [] +synonym: "positive regulation of IL-7 production" EXACT [] +synonym: "stimulation of interleukin-7 production" NARROW [] +synonym: "up regulation of interleukin-7 production" EXACT [] +synonym: "up-regulation of interleukin-7 production" EXACT [] +synonym: "upregulation of interleukin-7 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032676 ! regulation of interleukin-7 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032636 ! interleukin-7 production +relationship: positively_regulates GO:0032636 ! interleukin-7 production + +[Term] +id: GO:0032757 +name: positive regulation of interleukin-8 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-8 production." [GOC:mah] +synonym: "activation of interleukin-8 production" NARROW [] +synonym: "positive regulation of IL-8 production" EXACT [] +synonym: "stimulation of interleukin-8 production" NARROW [] +synonym: "up regulation of interleukin-8 production" EXACT [] +synonym: "up-regulation of interleukin-8 production" EXACT [] +synonym: "upregulation of interleukin-8 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032677 ! regulation of interleukin-8 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032637 ! interleukin-8 production +relationship: positively_regulates GO:0032637 ! interleukin-8 production + +[Term] +id: GO:0032758 +name: positive regulation of interleukin-9 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-9 production." [GOC:mah] +synonym: "activation of interleukin-9 production" NARROW [] +synonym: "positive regulation of IL-9 production" EXACT [] +synonym: "stimulation of interleukin-9 production" NARROW [] +synonym: "up regulation of interleukin-9 production" EXACT [] +synonym: "up-regulation of interleukin-9 production" EXACT [] +synonym: "upregulation of interleukin-9 production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0032678 ! regulation of interleukin-9 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032638 ! interleukin-9 production +relationship: positively_regulates GO:0032638 ! interleukin-9 production + +[Term] +id: GO:0032759 +name: positive regulation of TRAIL production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of TRAIL production." [GOC:mah] +synonym: "activation of TRAIL production" NARROW [] +synonym: "stimulation of TRAIL production" NARROW [] +synonym: "up regulation of TRAIL production" EXACT [] +synonym: "up-regulation of TRAIL production" EXACT [] +synonym: "upregulation of TRAIL production" EXACT [] +is_a: GO:0032679 ! regulation of TRAIL production +is_a: GO:1903557 ! positive regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032639 ! TRAIL production +relationship: positively_regulates GO:0032639 ! TRAIL production + +[Term] +id: GO:0032760 +name: positive regulation of tumor necrosis factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production." [GOC:mah] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "activation of tumor necrosis factor production" NARROW [] +synonym: "positive regulation of TNF production" EXACT [] +synonym: "positive regulation of TNF-alpha production" EXACT [] +synonym: "positive regulation of tumor necrosis factor-alpha production" EXACT [] +synonym: "stimulation of tumor necrosis factor production" NARROW [] +synonym: "up regulation of tumor necrosis factor production" EXACT [] +synonym: "up-regulation of tumor necrosis factor production" EXACT [] +synonym: "upregulation of tumor necrosis factor production" EXACT [] +is_a: GO:0032680 ! regulation of tumor necrosis factor production +is_a: GO:1903557 ! positive regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032640 ! tumor necrosis factor production +relationship: positively_regulates GO:0032640 ! tumor necrosis factor production + +[Term] +id: GO:0032761 +name: positive regulation of lymphotoxin A production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production." [GOC:mah] +synonym: "activation of lymphotoxin A production" NARROW [] +synonym: "positive regulation of LTA production" EXACT [] +synonym: "positive regulation of lymphotoxin-alpha production" EXACT [] +synonym: "positive regulation of TNF-beta production" EXACT [] +synonym: "positive regulation of tumor necrosis factor-beta production" EXACT [] +synonym: "stimulation of lymphotoxin A production" NARROW [] +synonym: "up regulation of lymphotoxin A production" EXACT [] +synonym: "up-regulation of lymphotoxin A production" EXACT [] +synonym: "upregulation of lymphotoxin A production" EXACT [] +is_a: GO:0032681 ! regulation of lymphotoxin A production +is_a: GO:1903557 ! positive regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032641 ! lymphotoxin A production +relationship: positively_regulates GO:0032641 ! lymphotoxin A production + +[Term] +id: GO:0032762 +name: mast cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a mast cell." [GOC:mah] +is_a: GO:0061082 ! myeloid leukocyte cytokine production + +[Term] +id: GO:0032763 +name: regulation of mast cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mast cell cytokine production." [GOC:mah] +is_a: GO:0002718 ! regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032762 ! mast cell cytokine production +relationship: regulates GO:0032762 ! mast cell cytokine production + +[Term] +id: GO:0032764 +name: negative regulation of mast cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production." [GOC:mah] +synonym: "down regulation of mast cell cytokine production" EXACT [] +synonym: "down-regulation of mast cell cytokine production" EXACT [] +synonym: "downregulation of mast cell cytokine production" EXACT [] +synonym: "inhibition of mast cell cytokine production" NARROW [] +is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response +is_a: GO:0032763 ! regulation of mast cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032762 ! mast cell cytokine production +relationship: negatively_regulates GO:0032762 ! mast cell cytokine production + +[Term] +id: GO:0032765 +name: positive regulation of mast cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production." [GOC:mah] +synonym: "activation of mast cell cytokine production" NARROW [] +synonym: "stimulation of mast cell cytokine production" NARROW [] +synonym: "up regulation of mast cell cytokine production" EXACT [] +synonym: "up-regulation of mast cell cytokine production" EXACT [] +synonym: "upregulation of mast cell cytokine production" EXACT [] +is_a: GO:0032763 ! regulation of mast cell cytokine production +is_a: GO:0061081 ! positive regulation of myeloid leukocyte cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032762 ! mast cell cytokine production +relationship: positively_regulates GO:0032762 ! mast cell cytokine production + +[Term] +id: GO:0032766 +name: NHE3/E3KARP/ACTN4 complex +namespace: cellular_component +def: "A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments." [PMID:11948184] +synonym: "NHE3/E3KARP/alpha-actinin complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0032767 +name: copper-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper." [GOC:ecd, PMID:16884690] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0032768 +name: regulation of monooxygenase activity +namespace: biological_process +def: "Any process that modulates the activity of a monooxygenase." [GOC:mah] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004497 ! monooxygenase activity +relationship: regulates GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0032769 +name: negative regulation of monooxygenase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of a monooxygenase." [GOC:mah] +synonym: "down regulation of monooxygenase activity" EXACT [] +synonym: "down-regulation of monooxygenase activity" EXACT [] +synonym: "downregulation of monooxygenase activity" EXACT [] +synonym: "inhibition of monooxygenase activity" NARROW [] +is_a: GO:0032768 ! regulation of monooxygenase activity +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004497 ! monooxygenase activity +relationship: negatively_regulates GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0032770 +name: positive regulation of monooxygenase activity +namespace: biological_process +def: "Any process that activates or increases the activity of a monooxygenase." [GOC:mah] +synonym: "activation of monooxygenase activity" NARROW [] +synonym: "stimulation of monooxygenase activity" NARROW [] +synonym: "up regulation of monooxygenase activity" EXACT [] +synonym: "up-regulation of monooxygenase activity" EXACT [] +synonym: "upregulation of monooxygenase activity" EXACT [] +is_a: GO:0032768 ! regulation of monooxygenase activity +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004497 ! monooxygenase activity +relationship: positively_regulates GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0032771 +name: regulation of monophenol monooxygenase activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb, PMID:2494997] +synonym: "regulation of monophenol oxygenase activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032768 ! regulation of monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004503 ! monophenol monooxygenase activity +relationship: regulates GO:0004503 ! monophenol monooxygenase activity + +[Term] +id: GO:0032772 +name: negative regulation of monophenol monooxygenase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb] +synonym: "down regulation of monophenol oxygenase activity" EXACT [] +synonym: "down-regulation of monophenol oxygenase activity" EXACT [] +synonym: "downregulation of monophenol oxygenase activity" EXACT [] +synonym: "inhibition of monophenol oxygenase activity" NARROW [] +synonym: "negative regulation of monophenol oxygenase activity" EXACT [GOC:dph, GOC:tb, PMID:2494997] +is_a: GO:0032769 ! negative regulation of monooxygenase activity +is_a: GO:0032771 ! regulation of monophenol monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004503 ! monophenol monooxygenase activity +relationship: negatively_regulates GO:0004503 ! monophenol monooxygenase activity + +[Term] +id: GO:0032773 +name: positive regulation of monophenol monooxygenase activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme monophenol oxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [GOC:dph, GOC:mah, GOC:tb, PMID:2494997] +synonym: "activation of monophenol oxygenase activity" NARROW [] +synonym: "positive regulation of monophenol oxygenase activity" EXACT [GOC:dph, GOC:tb, PMID:2494997] +synonym: "stimulation of monophenol oxygenase activity" NARROW [] +synonym: "up regulation of monophenol oxygenase activity" EXACT [] +synonym: "up-regulation of monophenol oxygenase activity" EXACT [] +synonym: "upregulation of monophenol oxygenase activity" EXACT [] +is_a: GO:0032770 ! positive regulation of monooxygenase activity +is_a: GO:0032771 ! regulation of monophenol monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004503 ! monophenol monooxygenase activity +relationship: positively_regulates GO:0004503 ! monophenol monooxygenase activity + +[Term] +id: GO:0032774 +name: RNA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] +comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. +synonym: "RNA anabolism" EXACT [] +synonym: "RNA biosynthesis" EXACT [] +synonym: "RNA formation" EXACT [] +synonym: "RNA synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0016070 ! RNA metabolic process +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process + +[Term] +id: GO:0032775 +name: DNA methylation on adenine +namespace: biological_process +def: "The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule." [GOC:pf] +synonym: "adenine methylation" RELATED [] +is_a: GO:0006306 ! DNA methylation + +[Term] +id: GO:0032776 +name: DNA methylation on cytosine +namespace: biological_process +def: "The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule." [GOC:pf] +synonym: "cytosine methylation" BROAD [] +is_a: GO:0006306 ! DNA methylation + +[Term] +id: GO:0032777 +name: Piccolo NuA4 histone acetyltransferase complex +namespace: cellular_component +def: "A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p." [GOC:rb, PMID:12782659, PMID:15964809] +is_a: GO:0035267 ! NuA4 histone acetyltransferase complex + +[Term] +id: GO:0032778 +name: ATPase-coupled cobalt transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015632 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in)." [GOC:mlg, GOC:mtg_transport, ISBN:0815340729] +synonym: "ATP-dependent cobalt transmembrane transporter activity" EXACT [] +synonym: "cobalt ABC transporter" RELATED [] +synonym: "cobalt porter activity" RELATED [] +synonym: "cobalt transporting ATPase activity" EXACT [] +synonym: "cobalt-transporting ATPase activity" EXACT [] +xref: RHEA:32779 +is_a: GO:0015087 ! cobalt ion transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity + +[Term] +id: GO:0032780 +name: negative regulation of ATPase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of ATP hydrolysis by an ATPase." [GOC:mah] +synonym: "down regulation of ATPase activity" EXACT [] +synonym: "down-regulation of ATPase activity" EXACT [] +synonym: "downregulation of ATPase activity" EXACT [] +synonym: "inhibition of ATPase activity" NARROW [] +synonym: "negative regulation of adenosinetriphosphatase activity" EXACT [] +is_a: GO:0043462 ! regulation of ATPase activity +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016887 ! ATPase activity +relationship: negatively_regulates GO:0016887 ! ATPase activity + +[Term] +id: GO:0032781 +name: positive regulation of ATPase activity +namespace: biological_process +def: "Any process that activates or increases the rate of ATP hydrolysis by an ATPase." [GOC:mah] +synonym: "activation of ATPase activity" NARROW [] +synonym: "positive regulation of adenosinetriphosphatase activity" EXACT [] +synonym: "stimulation of ATPase activity" NARROW [] +synonym: "up regulation of ATPase activity" EXACT [] +synonym: "up-regulation of ATPase activity" EXACT [] +synonym: "upregulation of ATPase activity" EXACT [] +is_a: GO:0043462 ! regulation of ATPase activity +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016887 ! ATPase activity +relationship: positively_regulates GO:0016887 ! ATPase activity + +[Term] +id: GO:0032782 +name: bile acid secretion +namespace: biological_process +def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0032783 +name: super elongation complex +namespace: cellular_component +def: "A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae." [PMID:17150956, PMID:30102332] +synonym: "ELL-EAF complex" NARROW [] +synonym: "ELL-EAF-EBP complex" NARROW [] +is_a: GO:0008023 ! transcription elongation factor complex +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17203 xsd:anyURI + +[Term] +id: GO:0032784 +name: regulation of DNA-templated transcription, elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH] +synonym: "regulation of DNA-dependent transcription, elongation" EXACT [GOC:txnOH] +synonym: "regulation of RNA elongation" BROAD [] +synonym: "regulation of transcription elongation, DNA-dependent" EXACT [GOC:jh2] +synonym: "regulation of transcriptional elongation" BROAD [] +synonym: "transcription elongation regulator activity" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006354 ! DNA-templated transcription, elongation +relationship: regulates GO:0006354 ! DNA-templated transcription, elongation + +[Term] +id: GO:0032785 +name: negative regulation of DNA-templated transcription, elongation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH] +synonym: "down regulation of RNA elongation" BROAD [] +synonym: "down-regulation of RNA elongation" BROAD [] +synonym: "downregulation of RNA elongation" BROAD [] +synonym: "inhibition of RNA elongation" BROAD [] +synonym: "negative regulation of DNA-dependent transcription, elongation" EXACT [GOC:txnOH] +synonym: "negative regulation of transcription elongation" BROAD [] +synonym: "negative regulation of transcription elongation, DNA-dependent" EXACT [GOC:jh2] +synonym: "negative regulation of transcriptional elongation" BROAD [] +synonym: "negative transcription elongation regulator activity" RELATED [] +is_a: GO:0032784 ! regulation of DNA-templated transcription, elongation +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006354 ! DNA-templated transcription, elongation +relationship: negatively_regulates GO:0006354 ! DNA-templated transcription, elongation + +[Term] +id: GO:0032786 +name: positive regulation of DNA-templated transcription, elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase." [GOC:mah, GOC:txnOH] +synonym: "activation of RNA elongation" BROAD [] +synonym: "positive regulation of DNA-dependent transcription, elongation" EXACT [GOC:txnOH] +synonym: "positive regulation of transcription elongation" BROAD [] +synonym: "positive regulation of transcription elongation, DNA-dependent" EXACT [GOC:jh2] +synonym: "positive regulation of transcriptional elongation" BROAD [] +synonym: "positive transcription elongation regulator activity" RELATED [] +synonym: "stimulation of RNA elongation" BROAD [] +synonym: "up regulation of RNA elongation" BROAD [] +synonym: "up-regulation of RNA elongation" BROAD [] +synonym: "upregulation of RNA elongation" BROAD [] +is_a: GO:0032784 ! regulation of DNA-templated transcription, elongation +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006354 ! DNA-templated transcription, elongation +relationship: positively_regulates GO:0006354 ! DNA-templated transcription, elongation + +[Term] +id: GO:0032787 +name: monocarboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk] +subset: goslim_yeast +synonym: "monocarboxylate metabolic process" EXACT [] +synonym: "monocarboxylic acid metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0032788 +name: saturated monocarboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds." [GOC:mah, GOC:vk] +synonym: "saturated monocarboxylate metabolic process" EXACT [] +synonym: "saturated monocarboxylic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0032789 +name: unsaturated monocarboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds." [GOC:mah, GOC:vk] +synonym: "unsaturated monocarboxylate metabolic process" EXACT [] +synonym: "unsaturated monocarboxylic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0032790 +name: ribosome disassembly +namespace: biological_process +def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk] +synonym: "ribosome dissociation factor" RELATED [] +synonym: "ribosome recycling" NARROW [GOC:db, PMID:9463391] +is_a: GO:1903008 ! organelle disassembly + +[Term] +id: GO:0032791 +name: lead ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lead (Pb) ions." [GOC:mah] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0032792 +name: negative regulation of CREB transcription factor activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] +synonym: "CREB inhibitor" RELATED [] +synonym: "inhibition of CREB transcription factor" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity + +[Term] +id: GO:0032793 +name: positive regulation of CREB transcription factor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] +synonym: "activation of CREB" EXACT [] +synonym: "activation of CREB transcription factor" EXACT [GOC:dph, GOC:tb] +synonym: "CREB activator" RELATED [] +is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity + +[Term] +id: GO:0032794 +name: GTPase activating protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a GTPase activating protein." [GOC:nln] +synonym: "GAP binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0032795 +name: heterotrimeric G-protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heterotrimeric G-protein." [GOC:nln] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0032796 +name: uropod organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated." [GOC:add, ISBN:0781735149, PMID:12714569, PMID:12787750] +synonym: "uropod organisation" EXACT [GOC:mah] +synonym: "uropod organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization + +[Term] +id: GO:0032797 +name: SMN complex +namespace: cellular_component +def: "A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus." [PMID:16434402, PMID:17023415] +comment: Note that a larger complex containing Sm proteins and other subunits is also sometimes referred to as the 'SMN complex'. The larger complex is represented by 'SMN-Sm protein complex ; GO:0034719'. +synonym: "SMN core complex" EXACT [] +synonym: "survival motor neuron complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032798 +name: Swi5-Sfr1 complex +namespace: cellular_component +def: "A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces)." [PMID:15620352, PMID:16921379] +comment: Note that this term refers to Schizosaccharomyces pombe Swi5, which should not be confused with the unrelated Saccharomyces Swi5p. +synonym: "Sae3-Mei5 complex" EXACT [GOC:elh, GOC:vw] +synonym: "Swi5 complex" BROAD [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0032799 +name: low-density lipoprotein receptor particle metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving low-density lipoprotein receptors." [GOC:vk] +synonym: "LDL receptor metabolic process" EXACT [] +synonym: "low-density lipoprotein receptor metabolic process" EXACT [GOC:bf, GOC:dph] +synonym: "low-density lipoprotein receptor metabolism" EXACT [] +is_a: GO:0043112 ! receptor metabolic process + +[Term] +id: GO:0032800 +name: receptor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah] +synonym: "receptor anabolism" EXACT [] +synonym: "receptor biosynthesis" EXACT [] +synonym: "receptor formation" EXACT [] +synonym: "receptor synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0043112 ! receptor metabolic process + +[Term] +id: GO:0032801 +name: receptor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah] +synonym: "receptor breakdown" EXACT [] +synonym: "receptor catabolism" EXACT [] +synonym: "receptor degradation" EXACT [] +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0043112 ! receptor metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0032802 +name: low-density lipoprotein particle receptor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:mah] +synonym: "LDL receptor breakdown" EXACT [] +synonym: "LDL receptor catabolic process" EXACT [] +synonym: "LDL receptor catabolism" RELATED [] +synonym: "LDL receptor degradation" EXACT [] +synonym: "low-density lipoprotein receptor breakdown" EXACT [] +synonym: "low-density lipoprotein receptor catabolic process" EXACT [GOC:dph] +synonym: "low-density lipoprotein receptor catabolism" EXACT [] +synonym: "low-density lipoprotein receptor degradation" EXACT [] +is_a: GO:0032799 ! low-density lipoprotein receptor particle metabolic process +is_a: GO:0032801 ! receptor catabolic process +is_a: GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0032803 +name: regulation of low-density lipoprotein particle receptor catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors." [GOC:mah] +synonym: "regulation of LDLr catabolic process" EXACT [] +synonym: "regulation of LDLr catabolism" EXACT [] +synonym: "regulation of low-density lipoprotein receptor breakdown" EXACT [] +synonym: "regulation of low-density lipoprotein receptor catabolic process" EXACT [GOC:bf, GOC:dph] +synonym: "regulation of low-density lipoprotein receptor catabolism" EXACT [] +synonym: "regulation of low-density lipoprotein receptor degradation" EXACT [] +is_a: GO:1903362 ! regulation of cellular protein catabolic process +is_a: GO:2000644 ! regulation of receptor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process +relationship: regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process + +[Term] +id: GO:0032804 +name: negative regulation of low-density lipoprotein particle receptor catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors." [GOC:mah] +synonym: "down regulation of low-density lipoprotein receptor catabolic process" EXACT [] +synonym: "down-regulation of low-density lipoprotein receptor catabolic process" EXACT [] +synonym: "downregulation of low-density lipoprotein receptor catabolic process" EXACT [] +synonym: "inhibition of low-density lipoprotein receptor catabolic process" NARROW [] +synonym: "negative regulation of low-density lipoprotein receptor breakdown" EXACT [] +synonym: "negative regulation of low-density lipoprotein receptor catabolic process" EXACT [GOC:dph] +synonym: "negative regulation of low-density lipoprotein receptor catabolism" EXACT [] +synonym: "negative regulation of low-density lipoprotein receptor degradation" EXACT [] +is_a: GO:0032803 ! regulation of low-density lipoprotein particle receptor catabolic process +is_a: GO:1903363 ! negative regulation of cellular protein catabolic process +is_a: GO:2000645 ! negative regulation of receptor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process +relationship: negatively_regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process + +[Term] +id: GO:0032805 +name: positive regulation of low-density lipoprotein particle receptor catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors." [GOC:mah] +synonym: "activation of low-density lipoprotein receptor catabolic process" NARROW [] +synonym: "positive regulation of low-density lipoprotein receptor breakdown" EXACT [] +synonym: "positive regulation of low-density lipoprotein receptor catabolic process" EXACT [GOC:bf, GOC:dph] +synonym: "positive regulation of low-density lipoprotein receptor catabolism" EXACT [] +synonym: "positive regulation of low-density lipoprotein receptor degradation" EXACT [] +synonym: "stimulation of low-density lipoprotein receptor catabolic process" NARROW [] +synonym: "up regulation of low-density lipoprotein receptor catabolic process" EXACT [] +synonym: "up-regulation of low-density lipoprotein receptor catabolic process" EXACT [] +synonym: "upregulation of low-density lipoprotein receptor catabolic process" EXACT [] +is_a: GO:0032803 ! regulation of low-density lipoprotein particle receptor catabolic process +is_a: GO:1903364 ! positive regulation of cellular protein catabolic process +is_a: GO:2000646 ! positive regulation of receptor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process +relationship: positively_regulates GO:0032802 ! low-density lipoprotein particle receptor catabolic process + +[Term] +id: GO:0032806 +name: carboxy-terminal domain protein kinase complex +namespace: cellular_component +def: "A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5." [PMID:15047695, PMID:16721054, PMID:17079683] +synonym: "CTDK complex" EXACT [] +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032807 +name: DNA ligase IV complex +namespace: cellular_component +def: "A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p." [PMID:16314503] +synonym: "DNA ligase IV-XRCC4 complex" EXACT [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0032808 +name: lacrimal gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye." [GOC:ln] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035272 ! exocrine system development + +[Term] +id: GO:0032809 +name: neuronal cell body membrane +namespace: cellular_component +def: "The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites." [GOC:jl] +synonym: "neuron cell body membrane" EXACT [] +synonym: "neuronal cell soma membrane" EXACT [] +is_a: GO:0044298 ! cell body membrane +relationship: part_of GO:0043025 ! neuronal cell body + +[Term] +id: GO:0032810 +name: sterol response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism." [GOC:vk, PMID:11994399] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "SRE binding" EXACT [] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding + +[Term] +id: GO:0032811 +name: negative regulation of epinephrine secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk] +synonym: "down regulation of epinephrine secretion" EXACT [] +synonym: "down-regulation of epinephrine secretion" EXACT [] +synonym: "downregulation of epinephrine secretion" EXACT [] +synonym: "inhibition of epinephrine secretion" NARROW [] +synonym: "negative regulation of adrenaline secretion" EXACT [] +is_a: GO:0014060 ! regulation of epinephrine secretion +is_a: GO:0033604 ! negative regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048242 ! epinephrine secretion +relationship: negatively_regulates GO:0048242 ! epinephrine secretion + +[Term] +id: GO:0032812 +name: positive regulation of epinephrine secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk] +synonym: "activation of epinephrine secretion" NARROW [] +synonym: "positive regulation of adrenaline secretion" EXACT [] +synonym: "stimulation of epinephrine secretion" NARROW [] +synonym: "up regulation of epinephrine secretion" EXACT [] +synonym: "up-regulation of epinephrine secretion" EXACT [] +synonym: "upregulation of epinephrine secretion" EXACT [] +is_a: GO:0014060 ! regulation of epinephrine secretion +is_a: GO:0033605 ! positive regulation of catecholamine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048242 ! epinephrine secretion +relationship: positively_regulates GO:0048242 ! epinephrine secretion + +[Term] +id: GO:0032813 +name: tumor necrosis factor receptor superfamily binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily." [GOC:add] +synonym: "TNF receptor superfamily binding" EXACT [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0032814 +name: regulation of natural killer cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell activation." [GOC:mah] +synonym: "regulation of NK cell activation" EXACT [] +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030101 ! natural killer cell activation +relationship: regulates GO:0030101 ! natural killer cell activation + +[Term] +id: GO:0032815 +name: negative regulation of natural killer cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation." [GOC:mah] +synonym: "down regulation of natural killer cell activation" EXACT [] +synonym: "down-regulation of natural killer cell activation" EXACT [] +synonym: "downregulation of natural killer cell activation" EXACT [] +synonym: "inhibition of natural killer cell activation" NARROW [] +synonym: "negative regulation of NK cell activation" EXACT [] +is_a: GO:0032814 ! regulation of natural killer cell activation +is_a: GO:0051250 ! negative regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030101 ! natural killer cell activation +relationship: negatively_regulates GO:0030101 ! natural killer cell activation + +[Term] +id: GO:0032816 +name: positive regulation of natural killer cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell activation." [GOC:mah] +synonym: "activation of natural killer cell activation" NARROW [] +synonym: "positive regulation of NK cell activation" EXACT [] +synonym: "stimulation of natural killer cell activation" NARROW [] +synonym: "up regulation of natural killer cell activation" EXACT [] +synonym: "up-regulation of natural killer cell activation" EXACT [] +synonym: "upregulation of natural killer cell activation" EXACT [] +is_a: GO:0032814 ! regulation of natural killer cell activation +is_a: GO:0051251 ! positive regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030101 ! natural killer cell activation +relationship: positively_regulates GO:0030101 ! natural killer cell activation + +[Term] +id: GO:0032817 +name: regulation of natural killer cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] +synonym: "regulation of NK cell proliferation" EXACT [] +is_a: GO:0032814 ! regulation of natural killer cell activation +is_a: GO:0050670 ! regulation of lymphocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001787 ! natural killer cell proliferation +relationship: regulates GO:0001787 ! natural killer cell proliferation + +[Term] +id: GO:0032818 +name: negative regulation of natural killer cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] +synonym: "down regulation of natural killer cell proliferation" EXACT [] +synonym: "down-regulation of natural killer cell proliferation" EXACT [] +synonym: "downregulation of natural killer cell proliferation" EXACT [] +synonym: "inhibition of natural killer cell proliferation" NARROW [] +synonym: "negative regulation of NK cell proliferation" EXACT [] +is_a: GO:0032815 ! negative regulation of natural killer cell activation +is_a: GO:0032817 ! regulation of natural killer cell proliferation +is_a: GO:0050672 ! negative regulation of lymphocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001787 ! natural killer cell proliferation +relationship: negatively_regulates GO:0001787 ! natural killer cell proliferation + +[Term] +id: GO:0032819 +name: positive regulation of natural killer cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] +synonym: "activation of natural killer cell proliferation" NARROW [] +synonym: "positive regulation of NK cell proliferation" EXACT [] +synonym: "stimulation of natural killer cell proliferation" NARROW [] +synonym: "up regulation of natural killer cell proliferation" EXACT [] +synonym: "up-regulation of natural killer cell proliferation" EXACT [] +synonym: "upregulation of natural killer cell proliferation" EXACT [] +is_a: GO:0032816 ! positive regulation of natural killer cell activation +is_a: GO:0032817 ! regulation of natural killer cell proliferation +is_a: GO:0050671 ! positive regulation of lymphocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001787 ! natural killer cell proliferation +relationship: positively_regulates GO:0001787 ! natural killer cell proliferation + +[Term] +id: GO:0032820 +name: regulation of natural killer cell proliferation involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah] +synonym: "regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb] +synonym: "regulation of NK cell proliferation during immune response" RELATED [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0032817 ! regulation of natural killer cell proliferation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002324 ! natural killer cell proliferation involved in immune response +relationship: regulates GO:0002324 ! natural killer cell proliferation involved in immune response + +[Term] +id: GO:0032821 +name: negative regulation of natural killer cell proliferation involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah] +synonym: "down regulation of natural killer cell proliferation during immune response" RELATED [] +synonym: "down-regulation of natural killer cell proliferation during immune response" RELATED [] +synonym: "downregulation of natural killer cell proliferation during immune response" RELATED [] +synonym: "inhibition of natural killer cell proliferation during immune response" NARROW [] +synonym: "negative regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb] +synonym: "negative regulation of NK cell proliferation during immune response" RELATED [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0032818 ! negative regulation of natural killer cell proliferation +is_a: GO:0032820 ! regulation of natural killer cell proliferation involved in immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response +relationship: negatively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response + +[Term] +id: GO:0032822 +name: positive regulation of natural killer cell proliferation involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response." [GOC:mah] +synonym: "activation of natural killer cell proliferation during immune response" NARROW [] +synonym: "positive regulation of natural killer cell proliferation during immune response" RELATED [GOC:tb] +synonym: "positive regulation of NK cell proliferation during immune response" RELATED [] +synonym: "stimulation of natural killer cell proliferation during immune response" NARROW [] +synonym: "up regulation of natural killer cell proliferation during immune response" RELATED [] +synonym: "up-regulation of natural killer cell proliferation during immune response" RELATED [] +synonym: "upregulation of natural killer cell proliferation during immune response" RELATED [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0032819 ! positive regulation of natural killer cell proliferation +is_a: GO:0032820 ! regulation of natural killer cell proliferation involved in immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response +relationship: positively_regulates GO:0002324 ! natural killer cell proliferation involved in immune response + +[Term] +id: GO:0032823 +name: regulation of natural killer cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of natural killer cell development" RELATED [GOC:add] +synonym: "regulation of NK cell differentiation" EXACT [] +is_a: GO:0032814 ! regulation of natural killer cell activation +is_a: GO:0045619 ! regulation of lymphocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001779 ! natural killer cell differentiation +relationship: regulates GO:0001779 ! natural killer cell differentiation + +[Term] +id: GO:0032824 +name: negative regulation of natural killer cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of natural killer cell differentiation" EXACT [] +synonym: "down-regulation of natural killer cell differentiation" EXACT [] +synonym: "downregulation of natural killer cell differentiation" EXACT [] +synonym: "inhibition of natural killer cell differentiation" NARROW [] +synonym: "negative regulation of natural killer cell development" RELATED [GOC:add] +synonym: "negative regulation of NK cell differentiation" EXACT [] +is_a: GO:0032815 ! negative regulation of natural killer cell activation +is_a: GO:0032823 ! regulation of natural killer cell differentiation +is_a: GO:0045620 ! negative regulation of lymphocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001779 ! natural killer cell differentiation +relationship: negatively_regulates GO:0001779 ! natural killer cell differentiation + +[Term] +id: GO:0032825 +name: positive regulation of natural killer cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of natural killer cell differentiation" NARROW [] +synonym: "positive regulation of natural killer cell development" RELATED [GOC:add] +synonym: "positive regulation of NK cell differentiation" EXACT [] +synonym: "stimulation of natural killer cell differentiation" NARROW [] +synonym: "up regulation of natural killer cell differentiation" EXACT [] +synonym: "up-regulation of natural killer cell differentiation" EXACT [] +synonym: "upregulation of natural killer cell differentiation" EXACT [] +is_a: GO:0032816 ! positive regulation of natural killer cell activation +is_a: GO:0032823 ! regulation of natural killer cell differentiation +is_a: GO:0045621 ! positive regulation of lymphocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001779 ! natural killer cell differentiation +relationship: positively_regulates GO:0001779 ! natural killer cell differentiation + +[Term] +id: GO:0032826 +name: regulation of natural killer cell differentiation involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of natural killer cell development involved in immune response" RELATED [GOC:add] +synonym: "regulation of natural killer cell differentiation during immune response" RELATED [GOC:tb] +synonym: "regulation of NK cell differentiation during immune response" RELATED [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0032823 ! regulation of natural killer cell differentiation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002325 ! natural killer cell differentiation involved in immune response +relationship: regulates GO:0002325 ! natural killer cell differentiation involved in immune response + +[Term] +id: GO:0032827 +name: negative regulation of natural killer cell differentiation involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of natural killer cell differentiation during immune response" RELATED [] +synonym: "down-regulation of natural killer cell differentiation during immune response" RELATED [] +synonym: "downregulation of natural killer cell differentiation during immune response" RELATED [] +synonym: "inhibition of natural killer cell differentiation during immune response" NARROW [] +synonym: "negative regulation of natural killer cell development involved in immune response" RELATED [GOC:add] +synonym: "negative regulation of natural killer cell differentiation during immune response" RELATED [GOC:tb] +synonym: "negative regulation of NK cell differentiation during immune response" RELATED [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0032824 ! negative regulation of natural killer cell differentiation +is_a: GO:0032826 ! regulation of natural killer cell differentiation involved in immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response +relationship: negatively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response + +[Term] +id: GO:0032828 +name: positive regulation of natural killer cell differentiation involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of natural killer cell differentiation during immune response" NARROW [] +synonym: "positive regulation of natural killer cell development involved in immune response" RELATED [GOC:add] +synonym: "positive regulation of natural killer cell differentiation during immune response" RELATED [GOC:tb] +synonym: "positive regulation of NK cell differentiation during immune response" RELATED [] +synonym: "stimulation of natural killer cell differentiation during immune response" NARROW [] +synonym: "up regulation of natural killer cell differentiation during immune response" RELATED [] +synonym: "up-regulation of natural killer cell differentiation during immune response" RELATED [] +synonym: "upregulation of natural killer cell differentiation during immune response" RELATED [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0032825 ! positive regulation of natural killer cell differentiation +is_a: GO:0032826 ! regulation of natural killer cell differentiation involved in immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response +relationship: positively_regulates GO:0002325 ! natural killer cell differentiation involved in immune response + +[Term] +id: GO:0032829 +name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development" RELATED [GOC:add] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] +is_a: GO:0043370 ! regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045589 ! regulation of regulatory T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +relationship: regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + +[Term] +id: GO:0032830 +name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +synonym: "down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +synonym: "downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +synonym: "inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development" RELATED [GOC:add] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] +is_a: GO:0032829 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +is_a: GO:0043371 ! negative regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045590 ! negative regulation of regulatory T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +relationship: negatively_regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + +[Term] +id: GO:0032831 +name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development" RELATED [GOC:add] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] +synonym: "up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +synonym: "up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +synonym: "upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] +is_a: GO:0032829 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +is_a: GO:0043372 ! positive regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045591 ! positive regulation of regulatory T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +relationship: positively_regulates GO:0002361 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + +[Term] +id: GO:0032832 +name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response" RELATED [GOC:add] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" RELATED [] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" RELATED [] +synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0032829 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +relationship: regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response + +[Term] +id: GO:0032833 +name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +synonym: "down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +synonym: "downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +synonym: "inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response" RELATED [GOC:add] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" RELATED [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" RELATED [] +synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" RELATED [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0032830 ! negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +is_a: GO:0032832 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +relationship: negatively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response + +[Term] +id: GO:0032834 +name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response." [GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response" RELATED [GOC:add] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [GOC:tb] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" RELATED [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" RELATED [] +synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" RELATED [] +synonym: "stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] +synonym: "up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +synonym: "up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +synonym: "upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" RELATED [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0032831 ! positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation +is_a: GO:0032832 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response +relationship: positively_regulates GO:0002298 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response + +[Term] +id: GO:0032835 +name: glomerulus development +namespace: biological_process +def: "The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment." [GOC:mah, GOC:mtg_kidney_jan10] +synonym: "glomerular development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0072006 ! nephron development + +[Term] +id: GO:0032836 +name: glomerular basement membrane development +namespace: biological_process +def: "The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration." [GOC:sr] +is_a: GO:0030198 ! extracellular matrix organization +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0032835 ! glomerulus development + +[Term] +id: GO:0032837 +name: distributive segregation +namespace: biological_process +def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally." [GOC:expert_rsh, GOC:ma, GOC:sart] +is_a: GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0032838 +name: plasma membrane bounded cell projection cytoplasm +namespace: cellular_component +def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah] +is_a: GO:0099568 ! cytoplasmic region +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0120025 ! plasma membrane bounded cell projection +relationship: part_of GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0032839 +name: dendrite cytoplasm +namespace: cellular_component +def: "All of the contents of a dendrite, excluding the surrounding plasma membrane." [GOC:mah] +synonym: "dendritic cytoplasm" EXACT [] +is_a: GO:0120111 ! neuron projection cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0030425 ! dendrite +relationship: part_of GO:0030425 ! dendrite + +[Term] +id: GO:0032840 +name: intramolecular proline-rich ligand binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proline-rich region within the same polypeptide." [GOC:pf] +synonym: "intramolecular proline-rich region binding" EXACT [] +is_a: GO:0043621 ! protein self-association +is_a: GO:0070064 ! proline-rich region binding + +[Term] +id: GO:0032841 +name: calcitonin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid." [GOC:ecd] +is_a: GO:0008144 ! drug binding +is_a: GO:0097644 ! calcitonin family binding + +[Term] +id: GO:0032843 +name: hydroperoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol." [GOC:mlg, PMID:12540833] +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0032847 +name: regulation of cellular pH reduction +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah] +synonym: "regulation of cell pH reduction" EXACT [] +synonym: "regulation of cellular acidification" EXACT [] +synonym: "regulation of intracellular acidification" RELATED [] +synonym: "regulation of intracellular pH reduction" EXACT [] +synonym: "regulation of reduction of cellular pH" EXACT [] +synonym: "regulation of reduction of pH in cell" EXACT [] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051453 ! regulation of intracellular pH +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051452 ! intracellular pH reduction +relationship: regulates GO:0051452 ! intracellular pH reduction + +[Term] +id: GO:0032848 +name: negative regulation of cellular pH reduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah] +synonym: "down regulation of cellular pH reduction" EXACT [] +synonym: "down-regulation of cellular pH reduction" EXACT [] +synonym: "downregulation of cellular pH reduction" EXACT [] +synonym: "inhibition of cellular pH reduction" NARROW [] +synonym: "negative regulation of cell pH reduction" EXACT [] +synonym: "negative regulation of cellular acidification" EXACT [] +synonym: "negative regulation of intracellular acidification" RELATED [] +synonym: "negative regulation of intracellular pH reduction" EXACT [] +synonym: "negative regulation of reduction of cellular pH" EXACT [] +synonym: "negative regulation of reduction of pH in cell" EXACT [] +is_a: GO:0032847 ! regulation of cellular pH reduction +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051454 ! intracellular pH elevation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051452 ! intracellular pH reduction +relationship: negatively_regulates GO:0051452 ! intracellular pH reduction + +[Term] +id: GO:0032849 +name: positive regulation of cellular pH reduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell." [GOC:mah] +synonym: "activation of cellular pH reduction" NARROW [] +synonym: "positive regulation of cell pH reduction" EXACT [] +synonym: "positive regulation of cellular acidification" EXACT [] +synonym: "positive regulation of intracellular acidification" RELATED [] +synonym: "positive regulation of intracellular pH reduction" EXACT [] +synonym: "positive regulation of reduction of cellular pH" EXACT [] +synonym: "positive regulation of reduction of pH in cell" EXACT [] +synonym: "stimulation of cellular pH reduction" NARROW [] +synonym: "up regulation of cellular pH reduction" EXACT [] +synonym: "up-regulation of cellular pH reduction" EXACT [] +synonym: "upregulation of cellular pH reduction" EXACT [] +is_a: GO:0032847 ! regulation of cellular pH reduction +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051452 ! intracellular pH reduction +relationship: positively_regulates GO:0051452 ! intracellular pH reduction + +[Term] +id: GO:0032865 +name: ERMES complex +namespace: cellular_component +def: "A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth." [GOC:mcc, PMID:19556461] +synonym: "ER-mitochondria encounter structure" EXACT [] +synonym: "Mdm10/Mdm12/Mmm1 complex" EXACT [] +synonym: "mitochore" EXACT [GOC:mcc] +synonym: "MMM1 complex" EXACT [GOC:mcc] +is_a: GO:0098799 ! outer mitochondrial membrane protein complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0044233 ! mitochondria-associated endoplasmic reticulum membrane + +[Term] +id: GO:0032866 +name: D-xylose:NADP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+." [PMID:12724380, PMID:15184173, RHEA:27445] +synonym: "D-xylose reductase activity" BROAD [] +synonym: "xylose reductase activity" BROAD [] +xref: MetaCyc:RXN-8773 +xref: RHEA:27445 +is_a: GO:0004032 ! alditol:NADP+ 1-oxidoreductase activity + +[Term] +id: GO:0032867 +name: L-arabinose:NADP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+." [PMID:12724380, PMID:15184173, RHEA:25229] +synonym: "arabinose reductase activity" BROAD [] +synonym: "arabinose:NADP reductase activity" BROAD [] +xref: KEGG_REACTION:R01759 +xref: MetaCyc:RXN-8772 +xref: RHEA:25229 +xref: SABIO-RK:1858 +is_a: GO:0004032 ! alditol:NADP+ 1-oxidoreductase activity + +[Term] +id: GO:0032868 +name: response to insulin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] +synonym: "response to insulin stimulus" EXACT [GOC:dos] +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0032869 +name: cellular response to insulin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] +is_a: GO:0032868 ! response to insulin +is_a: GO:0071375 ! cellular response to peptide hormone stimulus + +[Term] +id: GO:0032870 +name: cellular response to hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:mah] +is_a: GO:0009725 ! response to hormone +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0071495 ! cellular response to endogenous stimulus + +[Term] +id: GO:0032871 +name: regulation of karyogamy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] +is_a: GO:1903353 ! regulation of nucleus organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000741 ! karyogamy +relationship: regulates GO:0000741 ! karyogamy + +[Term] +id: GO:0032872 +name: regulation of stress-activated MAPK cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] +synonym: "regulation of p38 MAPK signaling" EXACT [] +synonym: "regulation of p38 MAPK signalling" EXACT [] +synonym: "regulation of stress-activated MAPK signaling pathway" EXACT [] +synonym: "regulation of stress-activated MAPK signalling pathway" EXACT [] +synonym: "regulation of stress-activated MAPKKK cascade" EXACT [] +synonym: "regulation of stress-activated MAPKKK signaling pathway" EXACT [] +synonym: "regulation of stress-activated MAPKKK signalling pathway" EXACT [] +is_a: GO:0043408 ! regulation of MAPK cascade +is_a: GO:0070302 ! regulation of stress-activated protein kinase signaling cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051403 ! stress-activated MAPK cascade +relationship: regulates GO:0051403 ! stress-activated MAPK cascade + +[Term] +id: GO:0032873 +name: negative regulation of stress-activated MAPK cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] +synonym: "down regulation of stress-activated MAPK cascade" EXACT [] +synonym: "down-regulation of stress-activated MAPK cascade" EXACT [] +synonym: "downregulation of stress-activated MAPK cascade" EXACT [] +synonym: "inhibition of stress-activated MAPK cascade" NARROW [] +synonym: "negative regulation of p38 MAPK signaling" EXACT [] +synonym: "negative regulation of p38 MAPK signalling" EXACT [] +synonym: "negative regulation of stress-activated MAPK signaling pathway" EXACT [] +synonym: "negative regulation of stress-activated MAPK signalling pathway" EXACT [] +synonym: "negative regulation of stress-activated MAPKKK cascade" EXACT [] +synonym: "negative regulation of stress-activated MAPKKK signaling pathway" EXACT [] +synonym: "negative regulation of stress-activated MAPKKK signalling pathway" EXACT [] +is_a: GO:0032872 ! regulation of stress-activated MAPK cascade +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0070303 ! negative regulation of stress-activated protein kinase signaling cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051403 ! stress-activated MAPK cascade +relationship: negatively_regulates GO:0051403 ! stress-activated MAPK cascade + +[Term] +id: GO:0032874 +name: positive regulation of stress-activated MAPK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] +synonym: "activation of stress-activated MAPK cascade" NARROW [] +synonym: "positive regulation of p38 MAPK signaling" EXACT [] +synonym: "positive regulation of p38 MAPK signalling" EXACT [] +synonym: "positive regulation of stress-activated MAPK signaling pathway" EXACT [] +synonym: "positive regulation of stress-activated MAPK signalling pathway" EXACT [] +synonym: "positive regulation of stress-activated MAPKKK cascade" EXACT [] +synonym: "positive regulation of stress-activated MAPKKK signaling pathway" EXACT [] +synonym: "positive regulation of stress-activated MAPKKK signalling pathway" EXACT [] +synonym: "stimulation of stress-activated MAPK cascade" NARROW [] +synonym: "up regulation of stress-activated MAPK cascade" EXACT [] +synonym: "up-regulation of stress-activated MAPK cascade" EXACT [] +synonym: "upregulation of stress-activated MAPK cascade" EXACT [] +is_a: GO:0032872 ! regulation of stress-activated MAPK cascade +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0070304 ! positive regulation of stress-activated protein kinase signaling cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051403 ! stress-activated MAPK cascade +relationship: positively_regulates GO:0051403 ! stress-activated MAPK cascade + +[Term] +id: GO:0032875 +name: regulation of DNA endoreduplication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA endoreduplication." [GOC:mah] +synonym: "regulation of DNA endoreplication" EXACT [] +synonym: "regulation of DNA re-duplication" EXACT [] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042023 ! DNA endoreduplication +relationship: regulates GO:0042023 ! DNA endoreduplication + +[Term] +id: GO:0032876 +name: negative regulation of DNA endoreduplication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." [GOC:mah] +synonym: "down regulation of DNA endoreduplication" EXACT [] +synonym: "down-regulation of DNA endoreduplication" EXACT [] +synonym: "downregulation of DNA endoreduplication" EXACT [] +synonym: "inhibition of DNA endoreduplication" NARROW [] +synonym: "negative regulation of DNA endoreplication" EXACT [] +synonym: "negative regulation of DNA re-duplication" EXACT [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0032875 ! regulation of DNA endoreduplication +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042023 ! DNA endoreduplication +relationship: negatively_regulates GO:0042023 ! DNA endoreduplication + +[Term] +id: GO:0032877 +name: positive regulation of DNA endoreduplication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." [GOC:mah] +synonym: "activation of DNA endoreduplication" NARROW [] +synonym: "positive regulation of DNA endoreplication" EXACT [] +synonym: "positive regulation of DNA re-duplication" EXACT [] +synonym: "stimulation of DNA endoreduplication" NARROW [] +synonym: "up regulation of DNA endoreduplication" EXACT [] +synonym: "up-regulation of DNA endoreduplication" EXACT [] +synonym: "upregulation of DNA endoreduplication" EXACT [] +is_a: GO:0032875 ! regulation of DNA endoreduplication +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042023 ! DNA endoreduplication +relationship: positively_regulates GO:0042023 ! DNA endoreduplication + +[Term] +id: GO:0032878 +name: regulation of establishment or maintenance of cell polarity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007163 ! establishment or maintenance of cell polarity +relationship: regulates GO:0007163 ! establishment or maintenance of cell polarity + +[Term] +id: GO:0032879 +name: regulation of localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "regulation of localisation" EXACT [GOC:mah] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051179 ! localization +relationship: regulates GO:0051179 ! localization + +[Term] +id: GO:0032880 +name: regulation of protein localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] +subset: goslim_chembl +synonym: "regulation of protein localisation" EXACT [GOC:mah] +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008104 ! protein localization +relationship: regulates GO:0008104 ! protein localization + +[Term] +id: GO:0032881 +name: regulation of polysaccharide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005976 ! polysaccharide metabolic process +relationship: regulates GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0032882 +name: regulation of chitin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah] +synonym: "regulation of chitin metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006030 ! chitin metabolic process +relationship: regulates GO:0006030 ! chitin metabolic process + +[Term] +id: GO:0032883 +name: regulation of chitin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah] +synonym: "regulation of chitin anabolism" EXACT [] +synonym: "regulation of chitin biosynthesis" RELATED [] +synonym: "regulation of chitin formation" EXACT [] +synonym: "regulation of chitin synthesis" EXACT [] +is_a: GO:0032882 ! regulation of chitin metabolic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006031 ! chitin biosynthetic process +relationship: regulates GO:0006031 ! chitin biosynthetic process + +[Term] +id: GO:0032884 +name: regulation of cell wall chitin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin." [GOC:mah] +synonym: "regulation of cell wall chitin anabolism" EXACT [] +synonym: "regulation of cell wall chitin biosynthesis" EXACT [] +synonym: "regulation of cell wall chitin formation" EXACT [] +synonym: "regulation of cell wall chitin synthesis" EXACT [] +is_a: GO:0032883 ! regulation of chitin biosynthetic process +is_a: GO:0034222 ! regulation of cell wall chitin metabolic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006038 ! cell wall chitin biosynthetic process +relationship: regulates GO:0006038 ! cell wall chitin biosynthetic process + +[Term] +id: GO:0032885 +name: regulation of polysaccharide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000271 ! polysaccharide biosynthetic process +relationship: regulates GO:0000271 ! polysaccharide biosynthetic process + +[Term] +id: GO:0032886 +name: regulation of microtubule-based process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007017 ! microtubule-based process +relationship: regulates GO:0007017 ! microtubule-based process + +[Term] +id: GO:0032887 +name: regulation of spindle elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle." [GOC:mah] +is_a: GO:0051983 ! regulation of chromosome segregation +is_a: GO:0090224 ! regulation of spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051231 ! spindle elongation +relationship: regulates GO:0051231 ! spindle elongation + +[Term] +id: GO:0032888 +name: regulation of mitotic spindle elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle." [GOC:mah] +is_a: GO:0032887 ! regulation of spindle elongation +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0060236 ! regulation of mitotic spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000022 ! mitotic spindle elongation +relationship: regulates GO:0000022 ! mitotic spindle elongation + +[Term] +id: GO:0032889 +name: regulation of vacuole fusion, non-autophagic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:mah] +is_a: GO:0044088 ! regulation of vacuole organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042144 ! vacuole fusion, non-autophagic +relationship: regulates GO:0042144 ! vacuole fusion, non-autophagic + +[Term] +id: GO:0032890 +name: regulation of organic acid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015849 ! organic acid transport +relationship: regulates GO:0015849 ! organic acid transport + +[Term] +id: GO:0032891 +name: negative regulation of organic acid transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of organic acid transport" EXACT [] +synonym: "down-regulation of organic acid transport" EXACT [] +synonym: "downregulation of organic acid transport" EXACT [] +synonym: "inhibition of organic acid transport" NARROW [] +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015849 ! organic acid transport +relationship: negatively_regulates GO:0015849 ! organic acid transport + +[Term] +id: GO:0032892 +name: positive regulation of organic acid transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of organic acid transport" NARROW [] +synonym: "stimulation of organic acid transport" NARROW [] +synonym: "up regulation of organic acid transport" EXACT [] +synonym: "up-regulation of organic acid transport" EXACT [] +synonym: "upregulation of organic acid transport" EXACT [] +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015849 ! organic acid transport +relationship: positively_regulates GO:0015849 ! organic acid transport + +[Term] +id: GO:0032896 +name: palmitoyl-CoA 9-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O." [GOC:kmv] +synonym: "palmitoyl-CoA delta9-desaturase acitivity" EXACT [] +is_a: GO:0016215 ! acyl-CoA desaturase activity + +[Term] +id: GO:0032897 +name: negative regulation of viral transcription +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription." [GOC:mah] +synonym: "down regulation of viral transcription" EXACT [] +synonym: "down-regulation of viral transcription" EXACT [] +synonym: "downregulation of viral transcription" EXACT [] +synonym: "inhibition of viral transcription" NARROW [] +is_a: GO:0046782 ! regulation of viral transcription +is_a: GO:0048525 ! negative regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019083 ! viral transcription +relationship: negatively_regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0032898 +name: neurotrophin production +namespace: biological_process +def: "The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth." [GOC:ecd, GOC:mah, GOC:mtg_MIT_16mar07] +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0032899 +name: regulation of neurotrophin production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032898 ! neurotrophin production +relationship: regulates GO:0032898 ! neurotrophin production + +[Term] +id: GO:0032900 +name: negative regulation of neurotrophin production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] +synonym: "down regulation of neurotrophin production" EXACT [] +synonym: "down-regulation of neurotrophin production" EXACT [] +synonym: "downregulation of neurotrophin production" EXACT [] +synonym: "inhibition of neurotrophin production" NARROW [] +is_a: GO:0032899 ! regulation of neurotrophin production +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032898 ! neurotrophin production +relationship: negatively_regulates GO:0032898 ! neurotrophin production + +[Term] +id: GO:0032901 +name: positive regulation of neurotrophin production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] +synonym: "activation of neurotrophin production" NARROW [] +synonym: "stimulation of neurotrophin production" NARROW [] +synonym: "up regulation of neurotrophin production" EXACT [] +synonym: "up-regulation of neurotrophin production" EXACT [] +synonym: "upregulation of neurotrophin production" EXACT [] +is_a: GO:0032899 ! regulation of neurotrophin production +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032898 ! neurotrophin production +relationship: positively_regulates GO:0032898 ! neurotrophin production + +[Term] +id: GO:0032902 +name: nerve growth factor production +namespace: biological_process +def: "The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels." [GOC:ecd, GOC:mah] +synonym: "beta-nerve growth factor production" EXACT [PR:000011194] +synonym: "NGF production" EXACT [] +is_a: GO:0032898 ! neurotrophin production + +[Term] +id: GO:0032903 +name: regulation of nerve growth factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF)." [GOC:mah] +synonym: "regulation of beta-nerve growth factor production" EXACT [PR:000011194] +synonym: "regulation of NGF production" EXACT [] +is_a: GO:0032899 ! regulation of neurotrophin production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032902 ! nerve growth factor production +relationship: regulates GO:0032902 ! nerve growth factor production + +[Term] +id: GO:0032904 +name: negative regulation of nerve growth factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF)." [GOC:mah] +synonym: "down regulation of nerve growth factor production" EXACT [] +synonym: "down-regulation of nerve growth factor production" EXACT [] +synonym: "downregulation of nerve growth factor production" EXACT [] +synonym: "inhibition of nerve growth factor production" NARROW [] +synonym: "negative regulation of NGF production" EXACT [] +is_a: GO:0032900 ! negative regulation of neurotrophin production +is_a: GO:0032903 ! regulation of nerve growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032902 ! nerve growth factor production +relationship: negatively_regulates GO:0032902 ! nerve growth factor production + +[Term] +id: GO:0032905 +name: transforming growth factor beta1 production +namespace: biological_process +def: "The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "TGF-B1 production" EXACT [] +synonym: "TGFB1 production" EXACT [] +synonym: "transforming growth factor-beta1 production" EXACT [GOC:bf] +is_a: GO:0071604 ! transforming growth factor beta production + +[Term] +id: GO:0032906 +name: transforming growth factor beta2 production +namespace: biological_process +def: "The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "TGF-B2 production" EXACT [] +synonym: "TGFB2 production" EXACT [] +synonym: "transforming growth factor-beta2 production" EXACT [GOC:bf] +is_a: GO:0071604 ! transforming growth factor beta production + +[Term] +id: GO:0032907 +name: transforming growth factor beta3 production +namespace: biological_process +def: "The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "TGF-B3 production" EXACT [] +synonym: "TGFB3 production" EXACT [] +synonym: "transforming growth factor-beta3 production" EXACT [GOC:bf] +is_a: GO:0071604 ! transforming growth factor beta production + +[Term] +id: GO:0032908 +name: regulation of transforming growth factor beta1 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah] +synonym: "regulation of TGF-B1 production" EXACT [] +synonym: "regulation of TGFB1 production" EXACT [] +synonym: "regulation of transforming growth factor-beta1 production" EXACT [GOC:bf] +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032905 ! transforming growth factor beta1 production +relationship: regulates GO:0032905 ! transforming growth factor beta1 production + +[Term] +id: GO:0032909 +name: regulation of transforming growth factor beta2 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah] +synonym: "regulation of TGF-B2 production" EXACT [] +synonym: "regulation of TGFB2 production" EXACT [] +synonym: "regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032906 ! transforming growth factor beta2 production +relationship: regulates GO:0032906 ! transforming growth factor beta2 production + +[Term] +id: GO:0032910 +name: regulation of transforming growth factor beta3 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah] +synonym: "regulation of TGF-B3 production" EXACT [] +synonym: "regulation of TGFB3 production" EXACT [] +synonym: "regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032907 ! transforming growth factor beta3 production +relationship: regulates GO:0032907 ! transforming growth factor beta3 production + +[Term] +id: GO:0032911 +name: negative regulation of transforming growth factor beta1 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah] +synonym: "down regulation of transforming growth factor-beta1 production" EXACT [] +synonym: "down-regulation of transforming growth factor-beta1 production" EXACT [] +synonym: "downregulation of transforming growth factor-beta1 production" EXACT [] +synonym: "inhibition of transforming growth factor-beta1 production" NARROW [] +synonym: "negative regulation of TGF-B1 production" EXACT [] +synonym: "negative regulation of TGFB1 production" EXACT [] +synonym: "negative regulation of transforming growth factor-beta1 production" EXACT [GOC:bf] +is_a: GO:0032908 ! regulation of transforming growth factor beta1 production +is_a: GO:0071635 ! negative regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032905 ! transforming growth factor beta1 production +relationship: negatively_regulates GO:0032905 ! transforming growth factor beta1 production + +[Term] +id: GO:0032912 +name: negative regulation of transforming growth factor beta2 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah] +synonym: "down regulation of transforming growth factor-beta2 production" EXACT [] +synonym: "down-regulation of transforming growth factor-beta2 production" EXACT [] +synonym: "downregulation of transforming growth factor-beta2 production" EXACT [] +synonym: "inhibition of transforming growth factor-beta2 production" NARROW [] +synonym: "negative regulation of TGF-B2 production" EXACT [] +synonym: "negative regulation of TGFB2 production" EXACT [] +synonym: "negative regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] +is_a: GO:0032909 ! regulation of transforming growth factor beta2 production +is_a: GO:0071635 ! negative regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032906 ! transforming growth factor beta2 production +relationship: negatively_regulates GO:0032906 ! transforming growth factor beta2 production + +[Term] +id: GO:0032913 +name: negative regulation of transforming growth factor beta3 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah] +synonym: "down regulation of transforming growth factor-beta3 production" EXACT [] +synonym: "down-regulation of transforming growth factor-beta3 production" EXACT [] +synonym: "downregulation of transforming growth factor-beta3 production" EXACT [] +synonym: "inhibition of transforming growth factor-beta3 production" NARROW [] +synonym: "negative regulation of TGF-B3 production" EXACT [] +synonym: "negative regulation of TGFB3 production" EXACT [] +synonym: "negative regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] +is_a: GO:0032910 ! regulation of transforming growth factor beta3 production +is_a: GO:0071635 ! negative regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032907 ! transforming growth factor beta3 production +relationship: negatively_regulates GO:0032907 ! transforming growth factor beta3 production + +[Term] +id: GO:0032914 +name: positive regulation of transforming growth factor beta1 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1." [GOC:mah] +synonym: "activation of transforming growth factor-beta1 production" NARROW [GOC:bf] +synonym: "positive regulation of TGF-B1 production" EXACT [] +synonym: "positive regulation of TGFB1 production" EXACT [] +synonym: "stimulation of transforming growth factor-beta1 production" NARROW [] +synonym: "up regulation of transforming growth factor-beta1 production" EXACT [] +synonym: "up-regulation of transforming growth factor-beta1 production" EXACT [] +synonym: "upregulation of transforming growth factor-beta1 production" EXACT [] +is_a: GO:0032908 ! regulation of transforming growth factor beta1 production +is_a: GO:0071636 ! positive regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032905 ! transforming growth factor beta1 production +relationship: positively_regulates GO:0032905 ! transforming growth factor beta1 production + +[Term] +id: GO:0032915 +name: positive regulation of transforming growth factor beta2 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2." [GOC:mah] +synonym: "activation of transforming growth factor-beta2 production" NARROW [] +synonym: "positive regulation of TGF-B2 production" EXACT [] +synonym: "positive regulation of TGFB2 production" EXACT [] +synonym: "positive regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] +synonym: "stimulation of transforming growth factor-beta2 production" NARROW [] +synonym: "up regulation of transforming growth factor-beta2 production" EXACT [] +synonym: "up-regulation of transforming growth factor-beta2 production" EXACT [] +synonym: "upregulation of transforming growth factor-beta2 production" EXACT [] +is_a: GO:0032909 ! regulation of transforming growth factor beta2 production +is_a: GO:0071636 ! positive regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032906 ! transforming growth factor beta2 production +relationship: positively_regulates GO:0032906 ! transforming growth factor beta2 production + +[Term] +id: GO:0032916 +name: positive regulation of transforming growth factor beta3 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3." [GOC:mah] +synonym: "activation of transforming growth factor-beta3 production" NARROW [] +synonym: "positive regulation of TGF-B3 production" EXACT [] +synonym: "positive regulation of TGFB3 production" EXACT [] +synonym: "positive regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] +synonym: "stimulation of transforming growth factor-beta3 production" NARROW [] +synonym: "up regulation of transforming growth factor-beta3 production" EXACT [] +synonym: "up-regulation of transforming growth factor-beta3 production" EXACT [] +synonym: "upregulation of transforming growth factor-beta3 production" EXACT [] +is_a: GO:0032910 ! regulation of transforming growth factor beta3 production +is_a: GO:0071636 ! positive regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032907 ! transforming growth factor beta3 production +relationship: positively_regulates GO:0032907 ! transforming growth factor beta3 production + +[Term] +id: GO:0032917 +name: polyamine acetylation +namespace: biological_process +def: "The modification of polyamines by addition of acetyl groups." [GOC:mlg] +is_a: GO:0006595 ! polyamine metabolic process + +[Term] +id: GO:0032918 +name: spermidine acetylation +namespace: biological_process +def: "The modification of spermidine by addition of acetyl groups." [GOC:mlg] +is_a: GO:0008216 ! spermidine metabolic process +is_a: GO:0032917 ! polyamine acetylation + +[Term] +id: GO:0032919 +name: spermine acetylation +namespace: biological_process +def: "The modification of spermine by addition of acetyl groups." [GOC:mlg] +is_a: GO:0008215 ! spermine metabolic process +is_a: GO:0032917 ! polyamine acetylation + +[Term] +id: GO:0032920 +name: putrescine acetylation +namespace: biological_process +def: "The modification of putrescine by addition of acetyl groups." [GOC:mlg] +is_a: GO:0009445 ! putrescine metabolic process +is_a: GO:0032917 ! polyamine acetylation + +[Term] +id: GO:0032921 +name: sarcosine oxidase complex +namespace: cellular_component +def: "A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity." [GOC:mah, GOC:mlg] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0032922 +name: circadian regulation of gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours." [GOC:mah] +synonym: "circadian regulation of protein expression" RELATED [] +synonym: "diurnal variation of gene expression" RELATED [] +synonym: "diurnal variation of protein expression" RELATED [] +is_a: GO:0007623 ! circadian rhythm +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0032923 +name: organic phosphonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included." [GOC:js] +synonym: "organophosphonate biosynthetic process" RELATED [] +is_a: GO:0019634 ! organic phosphonate metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0032924 +name: activin receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:rl, GOC:signaling] +synonym: "activin receptor signalling pathway" EXACT [] +is_a: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway + +[Term] +id: GO:0032925 +name: regulation of activin receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl] +synonym: "regulation of activin receptor signalling pathway" EXACT [] +synonym: "regulation of activin signaling pathway" RELATED [] +synonym: "regulation of activin signalling pathway" RELATED [] +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032924 ! activin receptor signaling pathway +relationship: regulates GO:0032924 ! activin receptor signaling pathway + +[Term] +id: GO:0032926 +name: negative regulation of activin receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl] +synonym: "down regulation of activin receptor signaling pathway" EXACT [] +synonym: "down-regulation of activin receptor signaling pathway" EXACT [] +synonym: "downregulation of activin receptor signaling pathway" EXACT [] +synonym: "inhibition of activin receptor signaling pathway" NARROW [] +synonym: "negative regulation of activin receptor signalling pathway" EXACT [] +synonym: "negative regulation of activin signaling pathway" RELATED [] +synonym: "negative regulation of activin signalling pathway" RELATED [] +is_a: GO:0032925 ! regulation of activin receptor signaling pathway +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032924 ! activin receptor signaling pathway +relationship: negatively_regulates GO:0032924 ! activin receptor signaling pathway + +[Term] +id: GO:0032927 +name: positive regulation of activin receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:BHF, GOC:rl] +synonym: "activation of activin receptor signaling pathway" NARROW [] +synonym: "positive regulation of activin receptor signalling pathway" EXACT [] +synonym: "positive regulation of activin signaling pathway" RELATED [] +synonym: "positive regulation of activin signalling pathway" RELATED [] +synonym: "stimulation of activin receptor signaling pathway" NARROW [] +synonym: "up regulation of activin receptor signaling pathway" EXACT [] +synonym: "up-regulation of activin receptor signaling pathway" EXACT [] +synonym: "upregulation of activin receptor signaling pathway" EXACT [] +is_a: GO:0032925 ! regulation of activin receptor signaling pathway +is_a: GO:0090100 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032924 ! activin receptor signaling pathway +relationship: positively_regulates GO:0032924 ! activin receptor signaling pathway + +[Term] +id: GO:0032928 +name: regulation of superoxide anion generation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] +synonym: "regulation of superoxide release" EXACT [GOC:dph, GOC:tb] +is_a: GO:0090322 ! regulation of superoxide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042554 ! superoxide anion generation +relationship: regulates GO:0042554 ! superoxide anion generation + +[Term] +id: GO:0032929 +name: negative regulation of superoxide anion generation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] +synonym: "down regulation of superoxide release" EXACT [] +synonym: "down-regulation of superoxide release" EXACT [] +synonym: "downregulation of superoxide release" EXACT [] +synonym: "inhibition of superoxide release" NARROW [] +synonym: "negative regulation of superoxide release" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032928 ! regulation of superoxide anion generation +is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042554 ! superoxide anion generation +relationship: negatively_regulates GO:0042554 ! superoxide anion generation + +[Term] +id: GO:0032930 +name: positive regulation of superoxide anion generation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] +synonym: "activation of superoxide release" NARROW [] +synonym: "positive regulation of superoxide release" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of superoxide release" NARROW [] +synonym: "up regulation of superoxide release" EXACT [] +synonym: "up-regulation of superoxide release" EXACT [] +synonym: "upregulation of superoxide release" EXACT [] +is_a: GO:0032928 ! regulation of superoxide anion generation +is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042554 ! superoxide anion generation +relationship: positively_regulates GO:0042554 ! superoxide anion generation + +[Term] +id: GO:0032931 +name: histone acetyltransferase activity (H3-K56 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K56 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0097043 ! histone H3-K56 acetylation + +[Term] +id: GO:0032932 +name: negative regulation of astral microtubule depolymerization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules." [GOC:mah] +synonym: "astral microtubule stabilization" EXACT [] +is_a: GO:0007026 ! negative regulation of microtubule depolymerization +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0090224 ! regulation of spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060172 ! astral microtubule depolymerization +relationship: negatively_regulates GO:0060172 ! astral microtubule depolymerization + +[Term] +id: GO:0032933 +name: SREBP signaling pathway +namespace: biological_process +alt_id: GO:0006994 +alt_id: GO:0030967 +alt_id: GO:0035104 +def: "A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription." [GOC:bf, GOC:mah, GOC:signaling, GOC:vw, PMID:12923525, PMID:22017871] +synonym: "activation of sterol regulatory element binding protein target gene transcription" NARROW [] +synonym: "endoplasmic reticulum to nucleus sterol response pathway" EXACT [] +synonym: "endoplasmic reticulum-nuclear sterol response pathway" EXACT [] +synonym: "ER to nucleus sterol response pathway" EXACT [] +synonym: "ER-nuclear sterol response pathway" EXACT [] +synonym: "positive regulation of sterol regulatory element binding protein target gene transcription" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of transcription via sterol regulatory element binding" NARROW [GOC:vw] +synonym: "positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway" NARROW [GOC:vw] +synonym: "SREBP signalling" EXACT [GOC:bf] +synonym: "SREBP target gene transcriptional activation" EXACT [] +synonym: "SREBP-mediated signaling pathway" RELATED [] +synonym: "SREBP-mediated signalling pathway" EXACT [] +synonym: "sterol depletion response, SREBP target gene transcriptional activation" EXACT [GOC:dph, GOC:mtg_lung] +synonym: "sterol regulatory element binding protein target gene transcriptional activation" BROAD [] +synonym: "sterol response element binding protein signaling pathway" EXACT [GOC:bf] +synonym: "stimulation of sterol regulatory element binding protein target gene transcription" NARROW [] +synonym: "up regulation of sterol regulatory element binding protein target gene transcription" EXACT [] +synonym: "up-regulation of sterol regulatory element binding protein target gene transcription" EXACT [] +synonym: "upregulation of sterol regulatory element binding protein target gene transcription" EXACT [] +is_a: GO:0006984 ! ER-nucleus signaling pathway +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0071501 ! cellular response to sterol depletion + +[Term] +id: GO:0032934 +name: sterol binding +namespace: molecular_function +alt_id: GO:0005498 +def: "Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [GOC:mah] +synonym: "sterol carrier activity" RELATED [GOC:mah] +is_a: GO:0005496 ! steroid binding + +[Term] +id: GO:0032935 +name: sterol sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol." [GOC:mah] +synonym: "sterol-sensing domain" NARROW [] +is_a: GO:0032934 ! sterol binding +is_a: GO:0106254 ! lipid sensor activity + +[Term] +id: GO:0032936 +name: SREBP-SCAP complex +namespace: cellular_component +def: "A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed." [PMID:12923525] +synonym: "Sre1-Scp1 complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex + +[Term] +id: GO:0032937 +name: SREBP-SCAP-Insig complex +namespace: cellular_component +def: "A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane." [PMID:12923525] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0030176 ! integral component of endoplasmic reticulum membrane + +[Term] +id: GO:0032938 +name: negative regulation of translation in response to oxidative stress +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] +is_a: GO:0032055 ! negative regulation of translation in response to stress +is_a: GO:0043556 ! regulation of translation in response to oxidative stress + +[Term] +id: GO:0032939 +name: positive regulation of translation in response to oxidative stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] +synonym: "activation of translation in response to oxidative stress" NARROW [] +synonym: "stimulation of translation in response to oxidative stress" NARROW [] +synonym: "up regulation of translation in response to oxidative stress" EXACT [] +synonym: "up-regulation of translation in response to oxidative stress" EXACT [] +synonym: "upregulation of translation in response to oxidative stress" EXACT [] +is_a: GO:0032056 ! positive regulation of translation in response to stress +is_a: GO:0043556 ! regulation of translation in response to oxidative stress + +[Term] +id: GO:0032940 +name: secretion by cell +namespace: biological_process +def: "The controlled release of a substance by a cell." [GOC:mah] +synonym: "cellular secretion" EXACT [] +xref: Wikipedia:Secretion +is_a: GO:0046903 ! secretion +is_a: GO:0140352 ! export from cell + +[Term] +id: GO:0032941 +name: secretion by tissue +namespace: biological_process +def: "The controlled release of a substance by a tissue." [GOC:mah] +synonym: "expulsion of gland contents" RELATED [GOC:mah] +synonym: "tissue secretion" EXACT [] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0046903 ! secretion + +[Term] +id: GO:0032942 +name: inositol tetrakisphosphate 2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP." [GOC:hf] +synonym: "1D-myo-inositol-tetrakisphosphate 2-kinase activity" EXACT [] +synonym: "inositol 1,3,4,6-tetrakisphosphate 2-kinase activity" EXACT [] +synonym: "inositol-tetrakisphosphate 2-kinase activity" EXACT [] +xref: EC:2.7.1 +is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity + +[Term] +id: GO:0032943 +name: mononuclear cell proliferation +namespace: biological_process +def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] +synonym: "PBMC proliferation" NARROW [] +synonym: "peripheral blood mononuclear cell proliferation" NARROW [] +is_a: GO:0070661 ! leukocyte proliferation + +[Term] +id: GO:0032944 +name: regulation of mononuclear cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] +synonym: "regulation of PBMC proliferation" NARROW [] +synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW [] +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032943 ! mononuclear cell proliferation +relationship: regulates GO:0032943 ! mononuclear cell proliferation + +[Term] +id: GO:0032945 +name: negative regulation of mononuclear cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] +synonym: "negative regulation of PBMC proliferation" NARROW [] +synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW [] +is_a: GO:0032944 ! regulation of mononuclear cell proliferation +is_a: GO:0070664 ! negative regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032943 ! mononuclear cell proliferation +relationship: negatively_regulates GO:0032943 ! mononuclear cell proliferation + +[Term] +id: GO:0032946 +name: positive regulation of mononuclear cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] +synonym: "activation of mononuclear cell proliferation" NARROW [] +synonym: "positive regulation of PBMC proliferation" NARROW [] +synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW [] +synonym: "stimulation of mononuclear cell proliferation" NARROW [] +synonym: "up regulation of mononuclear cell proliferation" EXACT [] +synonym: "up-regulation of mononuclear cell proliferation" EXACT [] +synonym: "upregulation of mononuclear cell proliferation" EXACT [] +is_a: GO:0032944 ! regulation of mononuclear cell proliferation +is_a: GO:0070665 ! positive regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032943 ! mononuclear cell proliferation +relationship: positively_regulates GO:0032943 ! mononuclear cell proliferation + +[Term] +id: GO:0032948 +name: regulation of alpha-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans." [GOC:mah] +synonym: "regulation of alpha-glucan metabolism" EXACT [] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030978 ! alpha-glucan metabolic process +relationship: regulates GO:0030978 ! alpha-glucan metabolic process + +[Term] +id: GO:0032949 +name: regulation of alpha-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans." [GOC:mah] +synonym: "regulation of alpha-glucan anabolism" EXACT [] +synonym: "regulation of alpha-glucan biosynthesis" EXACT [] +synonym: "regulation of alpha-glucan formation" EXACT [] +synonym: "regulation of alpha-glucan synthesis" EXACT [] +is_a: GO:0010962 ! regulation of glucan biosynthetic process +is_a: GO:0032948 ! regulation of alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030979 ! alpha-glucan biosynthetic process +relationship: regulates GO:0030979 ! alpha-glucan biosynthetic process + +[Term] +id: GO:0032950 +name: regulation of beta-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans." [GOC:mah] +synonym: "regulation of beta-glucan metabolism" EXACT [] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051273 ! beta-glucan metabolic process +relationship: regulates GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0032951 +name: regulation of beta-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans." [GOC:mah] +synonym: "regulation of beta-glucan anabolism" EXACT [] +synonym: "regulation of beta-glucan biosynthesis" EXACT [] +synonym: "regulation of beta-glucan formation" EXACT [] +synonym: "regulation of beta-glucan synthesis" EXACT [] +is_a: GO:0010962 ! regulation of glucan biosynthetic process +is_a: GO:0032950 ! regulation of beta-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051274 ! beta-glucan biosynthetic process +relationship: regulates GO:0051274 ! beta-glucan biosynthetic process + +[Term] +id: GO:0032952 +name: regulation of (1->3)-beta-D-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans." [GOC:mah] +synonym: "regulation of (1->3)-beta-D-glucan metabolism" EXACT [] +synonym: "regulation of 1,3-beta-D-glucan metabolic process" EXACT [] +synonym: "regulation of 1,3-beta-glucan metabolic process" BROAD [] +synonym: "regulation of 1,3-beta-glucan metabolism" EXACT [] +is_a: GO:0032950 ! regulation of beta-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006074 ! (1->3)-beta-D-glucan metabolic process +relationship: regulates GO:0006074 ! (1->3)-beta-D-glucan metabolic process + +[Term] +id: GO:0032953 +name: regulation of (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans." [GOC:mah] +synonym: "regulation of 1,3-beta-glucan anabolism" EXACT [] +synonym: "regulation of 1,3-beta-glucan biosynthesis" EXACT [] +synonym: "regulation of 1,3-beta-glucan biosynthetic process" BROAD [] +synonym: "regulation of 1,3-beta-glucan formation" EXACT [] +synonym: "regulation of 1,3-beta-glucan synthesis" EXACT [] +is_a: GO:0032951 ! regulation of beta-glucan biosynthetic process +is_a: GO:0032952 ! regulation of (1->3)-beta-D-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +relationship: regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process + +[Term] +id: GO:0032954 +name: regulation of cytokinetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a cytokinetic process." [GOC:mah] +is_a: GO:0032465 ! regulation of cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032506 ! cytokinetic process +relationship: regulates GO:0032506 ! cytokinetic process + +[Term] +id: GO:0032955 +name: regulation of division septum assembly +namespace: biological_process +alt_id: GO:1901138 +alt_id: GO:1902468 +def: "Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [GOC:mtg_cell_cycle, PMID:19959363, PMID:21246752, PMID:22786806] +synonym: "regulation of division septum formation" EXACT [] +is_a: GO:1901891 ! regulation of cell septum assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0000917 ! division septum assembly +relationship: regulates GO:0000917 ! division septum assembly + +[Term] +id: GO:0032956 +name: regulation of actin cytoskeleton organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] +synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah] +synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0032970 ! regulation of actin filament-based process +is_a: GO:0051493 ! regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030036 ! actin cytoskeleton organization +relationship: regulates GO:0030036 ! actin cytoskeleton organization + +[Term] +id: GO:0032957 +name: inositol trisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached." [GOC:mah] +synonym: "inositol trisphosphate metabolism" EXACT [] +synonym: "IP3 metabolic process" EXACT [] +synonym: "IP3 metabolism" EXACT [] +synonym: "myo-inositol trisphosphate metabolic process" NARROW [] +is_a: GO:0043647 ! inositol phosphate metabolic process + +[Term] +id: GO:0032958 +name: inositol phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:mah] +synonym: "inositol phosphate anabolism" EXACT [] +synonym: "inositol phosphate biosynthesis" EXACT [] +synonym: "inositol phosphate formation" EXACT [] +synonym: "inositol phosphate synthesis" EXACT [] +synonym: "myo-inositol phosphate biosynthetic process" NARROW [] +is_a: GO:0043647 ! inositol phosphate metabolic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0032959 +name: inositol trisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached." [GOC:mah] +synonym: "inositol trisphosphate anabolism" EXACT [] +synonym: "inositol trisphosphate biosynthesis" EXACT [] +synonym: "inositol trisphosphate formation" EXACT [] +synonym: "inositol trisphosphate synthesis" EXACT [] +synonym: "IP3 biosynthesis" EXACT [] +synonym: "IP3 biosynthetic process" EXACT [] +synonym: "myo-inositol trisphosphate biosynthetic process" NARROW [] +is_a: GO:0032957 ! inositol trisphosphate metabolic process +is_a: GO:0032958 ! inositol phosphate biosynthetic process + +[Term] +id: GO:0032960 +name: regulation of inositol trisphosphate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] +synonym: "regulation of inositol trisphosphate anabolism" EXACT [] +synonym: "regulation of inositol trisphosphate biosynthesis" EXACT [] +synonym: "regulation of inositol trisphosphate formation" EXACT [] +synonym: "regulation of inositol trisphosphate synthesis" EXACT [] +synonym: "regulation of IP3 biosynthesis" EXACT [] +synonym: "regulation of IP3 biosynthetic process" EXACT [] +synonym: "regulation of myo-inositol trisphosphate biosynthesis" NARROW [] +synonym: "regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] +is_a: GO:0010919 ! regulation of inositol phosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032959 ! inositol trisphosphate biosynthetic process +relationship: regulates GO:0032959 ! inositol trisphosphate biosynthetic process + +[Term] +id: GO:0032961 +name: negative regulation of inositol trisphosphate biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] +synonym: "negative regulation of inositol trisphosphate anabolism" EXACT [] +synonym: "negative regulation of inositol trisphosphate biosynthesis" EXACT [] +synonym: "negative regulation of inositol trisphosphate formation" EXACT [] +synonym: "negative regulation of inositol trisphosphate synthesis" EXACT [] +synonym: "negative regulation of IP3 biosynthesis" EXACT [] +synonym: "negative regulation of IP3 biosynthetic process" EXACT [] +synonym: "negative regulation of myo-inositol trisphosphate biosynthesis" NARROW [] +synonym: "negative regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] +is_a: GO:0010920 ! negative regulation of inositol phosphate biosynthetic process +is_a: GO:0032960 ! regulation of inositol trisphosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032959 ! inositol trisphosphate biosynthetic process +relationship: negatively_regulates GO:0032959 ! inositol trisphosphate biosynthetic process + +[Term] +id: GO:0032962 +name: positive regulation of inositol trisphosphate biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] +synonym: "positive regulation of inositol trisphosphate anabolism" EXACT [] +synonym: "positive regulation of inositol trisphosphate biosynthesis" EXACT [] +synonym: "positive regulation of inositol trisphosphate formation" EXACT [] +synonym: "positive regulation of inositol trisphosphate synthesis" EXACT [] +synonym: "positive regulation of IP3 biosynthesis" EXACT [] +synonym: "positive regulation of IP3 biosynthetic process" EXACT [] +synonym: "positive regulation of myo-inositol trisphosphate biosynthesis" NARROW [] +synonym: "positive regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] +is_a: GO:0032960 ! regulation of inositol trisphosphate biosynthetic process +is_a: GO:0060732 ! positive regulation of inositol phosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032959 ! inositol trisphosphate biosynthetic process +relationship: positively_regulates GO:0032959 ! inositol trisphosphate biosynthetic process + +[Term] +id: GO:0032963 +name: collagen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] +synonym: "collagen metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0032964 +name: collagen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] +synonym: "collagen anabolism" EXACT [] +synonym: "collagen biosynthesis" EXACT [] +synonym: "collagen formation" EXACT [] +synonym: "collagen synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0032963 ! collagen metabolic process + +[Term] +id: GO:0032965 +name: regulation of collagen biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] +synonym: "regulation of collagen anabolism" EXACT [] +synonym: "regulation of collagen biosynthesis" EXACT [] +synonym: "regulation of collagen formation" EXACT [] +synonym: "regulation of collagen synthesis" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0010712 ! regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032964 ! collagen biosynthetic process +relationship: regulates GO:0032964 ! collagen biosynthetic process + +[Term] +id: GO:0032966 +name: negative regulation of collagen biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] +synonym: "negative regulation of collagen anabolism" EXACT [] +synonym: "negative regulation of collagen biosynthesis" EXACT [] +synonym: "negative regulation of collagen formation" EXACT [] +synonym: "negative regulation of collagen synthesis" EXACT [] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0010713 ! negative regulation of collagen metabolic process +is_a: GO:0032965 ! regulation of collagen biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032964 ! collagen biosynthetic process +relationship: negatively_regulates GO:0032964 ! collagen biosynthetic process + +[Term] +id: GO:0032967 +name: positive regulation of collagen biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] +synonym: "positive regulation of collagen anabolism" EXACT [] +synonym: "positive regulation of collagen biosynthesis" EXACT [] +synonym: "positive regulation of collagen formation" EXACT [] +synonym: "positive regulation of collagen synthesis" EXACT [] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0010714 ! positive regulation of collagen metabolic process +is_a: GO:0032965 ! regulation of collagen biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032964 ! collagen biosynthetic process +relationship: positively_regulates GO:0032964 ! collagen biosynthetic process + +[Term] +id: GO:0032968 +name: positive regulation of transcription elongation from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:0090040 +def: "Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah, GOC:txnOH] +synonym: "positive regulation of gene-specific transcription elongation from RNA polymerase II promoter" RELATED [] +synonym: "positive regulation of RNA elongation from RNA polymerase II promoter" EXACT [] +is_a: GO:0032786 ! positive regulation of DNA-templated transcription, elongation +is_a: GO:0034243 ! regulation of transcription elongation from RNA polymerase II promoter +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter +relationship: positively_regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter + +[Term] +id: GO:0032969 +name: endosomal scaffold complex +namespace: cellular_component +def: "A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling." [PMID:15263099, PMID:16227978, PMID:17496910] +synonym: "endosomal adaptor complex" EXACT [GOC:hjd] +synonym: "MP1-p14 scaffolding complex" EXACT [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0031902 ! late endosome membrane + +[Term] +id: GO:0032970 +name: regulation of actin filament-based process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030029 ! actin filament-based process +relationship: regulates GO:0030029 ! actin filament-based process + +[Term] +id: GO:0032971 +name: regulation of muscle filament sliding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle filament sliding." [GOC:ecd] +is_a: GO:0006937 ! regulation of muscle contraction +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030049 ! muscle filament sliding +relationship: regulates GO:0030049 ! muscle filament sliding + +[Term] +id: GO:0032972 +name: regulation of muscle filament sliding speed +namespace: biological_process +def: "Any process that modulates the velocity of muscle filament sliding." [GOC:dph, GOC:ecd, GOC:tb] +is_a: GO:0032971 ! regulation of muscle filament sliding +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0032973 +name: amino acid export across plasma membrane +namespace: biological_process +alt_id: GO:0044746 +def: "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:jl] +synonym: "amino acid efflux" EXACT [] +synonym: "amino acid export" BROAD [] +synonym: "amino acid transmembrane export" BROAD [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +created_by: jl +creation_date: 2012-11-14T14:27:40Z + +[Term] +id: GO:0032974 +name: amino acid transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of amino acids out of the vacuole, across the vacuolar membrane." [GOC:mah] +synonym: "amino acid efflux from vacuole" EXACT [] +synonym: "vacuolar amino acid export" EXACT [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0034486 ! vacuolar transmembrane transport + +[Term] +id: GO:0032975 +name: amino acid transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of amino acids into the vacuole across the vacuolar membrane." [GOC:mah] +synonym: "vacuolar amino acid import" EXACT [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0043090 ! amino acid import + +[Term] +id: GO:0032976 +name: release of matrix enzymes from mitochondria +namespace: biological_process +def: "The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process." [GOC:mah, GOC:mtg_apoptosis, PMID:9843949] +comment: Annotation to this term should be done with caution, particularly if the mechanism is not well clarified. +synonym: "mAST release from mitochondria" NARROW [] +synonym: "release of aspartate aminotransferase from mitochondria" NARROW [] +is_a: GO:0008637 ! apoptotic mitochondrial changes + +[Term] +id: GO:0032977 +name: membrane insertase activity +namespace: molecular_function +def: "Mediates the integration of proteins into a membrane from the inner side of the membrane. Membrane insertases are highly conserved and include the bacterial YidC family, the plant chloroplast Alb3 family, and the fungal and animal mitochondrial Oxa1/Cox18 family." [PMID:14739936] +xref: Reactome:R-HSA-1268025 "SAM50 complex inserts proteins into mitochondrial outer membrane" +xref: Reactome:R-HSA-1299482 "TIMM23 SORT inserts proteins into inner membrane" +xref: Reactome:R-HSA-1307803 "TIMM22 inserts proteins into inner membrane" +is_a: GO:0140104 ! molecular carrier activity +relationship: part_of GO:0090150 ! establishment of protein localization to membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16976 xsd:anyURI + +[Term] +id: GO:0032978 +name: protein insertion into membrane from inner side +namespace: biological_process +def: "The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side." [PMID:14739936, PMID:15473843] +synonym: "insertion of proteins into membrane from the inner side" EXACT [] +is_a: GO:0051205 ! protein insertion into membrane + +[Term] +id: GO:0032979 +name: protein insertion into mitochondrial inner membrane from matrix +namespace: biological_process +def: "The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix." [GOC:vw, PMID:12880202, PMID:15473843] +synonym: "insertion of proteins into the mitochondrial membrane from the inner side" EXACT [] +synonym: "protein insertion into mitochondrial inner membrane from matrix side" EXACT [] +synonym: "protein insertion into mitochondrial membrane from inner side" EXACT [] +is_a: GO:0006839 ! mitochondrial transport +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0032978 ! protein insertion into membrane from inner side +is_a: GO:0090151 ! establishment of protein localization to mitochondrial membrane + +[Term] +id: GO:0032980 +name: keratinocyte activation +namespace: biological_process +def: "A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines." [GOC:mah, PMID:15737202] +is_a: GO:0001775 ! cell activation + +[Term] +id: GO:0032981 +name: mitochondrial respiratory chain complex I assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I." [GOC:rph] +synonym: "mitochondrial complex I assembly" EXACT [] +synonym: "mitochondrial NADH dehydrogenase complex (ubiquinone) assembly" EXACT [] +is_a: GO:0010257 ! NADH dehydrogenase complex assembly +is_a: GO:0033108 ! mitochondrial respiratory chain complex assembly + +[Term] +id: GO:0032982 +name: myosin filament +namespace: cellular_component +def: "A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament." [GOC:mah] +synonym: "myosin thick filament" RELATED [] +synonym: "thick filament" RELATED [] +is_a: GO:0099512 ! supramolecular fiber +relationship: has_part GO:0016459 ! myosin complex + +[Term] +id: GO:0032983 +name: kainate selective glutamate receptor complex +namespace: cellular_component +def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits." [GOC:bf, http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html, PMID:18655795] +is_a: GO:0008328 ! ionotropic glutamate receptor complex +is_a: GO:0034705 ! potassium channel complex +is_a: GO:0034706 ! sodium channel complex + +[Term] +id: GO:0032984 +name: protein-containing complex disassembly +namespace: biological_process +alt_id: GO:0034623 +alt_id: GO:0043241 +def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah] +synonym: "cellular macromolecule complex disassembly" RELATED [] +synonym: "macromolecule complex disassembly" RELATED [] +synonym: "protein complex disassembly" EXACT [] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0043933 ! protein-containing complex subunit organization + +[Term] +id: GO:0032985 +name: protein-carbohydrate complex disassembly +namespace: biological_process +def: "The disaggregation of a protein-carbohydrate complex into its constituent components." [GOC:mah] +is_a: GO:0032984 ! protein-containing complex disassembly +is_a: GO:0071823 ! protein-carbohydrate complex subunit organization + +[Term] +id: GO:0032986 +name: protein-DNA complex disassembly +namespace: biological_process +def: "The disaggregation of a protein-DNA complex into its constituent components." [GOC:mah] +synonym: "DNA-protein complex disassembly" EXACT [GOC:mah] +is_a: GO:0032984 ! protein-containing complex disassembly +is_a: GO:0071824 ! protein-DNA complex subunit organization + +[Term] +id: GO:0032987 +name: protein-lipid complex disassembly +namespace: biological_process +def: "The disaggregation of a protein-lipid complex into its constituent components." [GOC:mah] +is_a: GO:0032984 ! protein-containing complex disassembly +is_a: GO:0071825 ! protein-lipid complex subunit organization + +[Term] +id: GO:0032988 +name: ribonucleoprotein complex disassembly +namespace: biological_process +def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah] +synonym: "protein-RNA complex disassembly" EXACT [] +synonym: "RNA-protein complex disassembly" EXACT [] +synonym: "RNP complex disassembly" EXACT [] +is_a: GO:0032984 ! protein-containing complex disassembly +is_a: GO:0071826 ! ribonucleoprotein complex subunit organization + +[Term] +id: GO:0032989 +name: cellular component morphogenesis +namespace: biological_process +def: "The process in which cellular structures, including whole cells or cell parts, are generated and organized." [GOC:dph, GOC:mah, GOC:tb] +subset: goslim_pir +synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0016043 ! cellular component organization +is_a: GO:0048869 ! cellular developmental process + +[Term] +id: GO:0032990 +name: cell part morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a cell part are generated and organized." [GOC:mah] +is_a: GO:0032989 ! cellular component morphogenesis + +[Term] +id: GO:0032991 +name: protein-containing complex +namespace: cellular_component +alt_id: GO:0043234 +def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah] +comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_pir +synonym: "macromolecular complex" EXACT [] +synonym: "macromolecule complex" EXACT [] +synonym: "protein complex" NARROW [] +synonym: "protein containing complex" EXACT [] +synonym: "protein-protein complex" NARROW [] +is_a: GO:0005575 ! cellular_component + +[Term] +id: GO:0032992 +name: protein-carbohydrate complex +namespace: cellular_component +def: "A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other." [GOC:mah] +comment: Macromolecular complexes in which the carbohydrate component is all covalently bound to protein are not considered protein carbohydrate complexes. +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0032993 +name: protein-DNA complex +namespace: cellular_component +def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah] +comment: Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here. +subset: goslim_pir +synonym: "DNA-protein complex" EXACT [GOC:mah] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0032994 +name: protein-lipid complex +namespace: cellular_component +def: "A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other." [GOC:mah] +comment: Macromolecular complexes in which the lipid component is all covalently bound to protein are not considered protein-lipid complexes. +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0032995 +name: regulation of fungal-type cell wall biogenesis +namespace: biological_process +def: "Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of chitin- and beta-glucan-containing cell wall biogenesis" RELATED [GOC:mah] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009272 ! fungal-type cell wall biogenesis +relationship: regulates GO:0009272 ! fungal-type cell wall biogenesis + +[Term] +id: GO:0032996 +name: Bcl3-Bcl10 complex +namespace: cellular_component +def: "A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus." [PMID:16280327] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0032997 +name: Fc receptor complex +namespace: cellular_component +def: "A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin." [GOC:add, ISBN:0781735149] +subset: goslim_pir +synonym: "Fc-receptor complex" EXACT [] +synonym: "FcR complex" EXACT [] +synonym: "immunoglobulin receptor complex" BROAD [] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0032998 +name: Fc-epsilon receptor I complex +namespace: cellular_component +def: "A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE." [GOC:add, ISBN:0781735149] +synonym: "FceRI complex" EXACT [] +synonym: "IgE receptor complex" BROAD [] +synonym: "immunoglobulin E receptor complex" BROAD [] +is_a: GO:0032997 ! Fc receptor complex + +[Term] +id: GO:0032999 +name: Fc-alpha receptor I complex +namespace: cellular_component +def: "A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA." [GOC:add, ISBN:0781735149, PMID:12524384] +synonym: "FcaRI complex" EXACT [] +synonym: "IgA receptor complex" BROAD [] +synonym: "immunoglobulin A receptor complex" BROAD [] +is_a: GO:0032997 ! Fc receptor complex + +[Term] +id: GO:0033000 +name: Fc-gamma receptor I complex +namespace: cellular_component +def: "A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG." [GOC:add, ISBN:0781735149, PMID:11244038, PMID:12413532] +synonym: "FcgRI complex" EXACT [] +synonym: "IgG receptor complex" BROAD [] +synonym: "immunoglobulin G receptor complex" BROAD [] +is_a: GO:0032997 ! Fc receptor complex + +[Term] +id: GO:0033001 +name: Fc-gamma receptor III complex +namespace: cellular_component +def: "A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG." [GOC:add, ISBN:0781735149, PMID:11244038, PMID:12413532] +synonym: "FcgRIII complex" EXACT [] +synonym: "IgG receptor complex" BROAD [] +synonym: "immunoglobulin G receptor complex" BROAD [] +is_a: GO:0032997 ! Fc receptor complex + +[Term] +id: GO:0033002 +name: muscle cell proliferation +namespace: biological_process +def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] +synonym: "myocyte proliferation" EXACT [] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0033003 +name: regulation of mast cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mast cell activation." [GOC:mah] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045576 ! mast cell activation +relationship: regulates GO:0045576 ! mast cell activation + +[Term] +id: GO:0033004 +name: negative regulation of mast cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation." [GOC:mah] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:0033003 ! regulation of mast cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045576 ! mast cell activation +relationship: negatively_regulates GO:0045576 ! mast cell activation + +[Term] +id: GO:0033005 +name: positive regulation of mast cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of mast cell activation." [GOC:mah] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:0033003 ! regulation of mast cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045576 ! mast cell activation +relationship: positively_regulates GO:0045576 ! mast cell activation + +[Term] +id: GO:0033006 +name: regulation of mast cell activation involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response." [GOC:mah] +synonym: "regulation of mast cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0033003 ! regulation of mast cell activation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002279 ! mast cell activation involved in immune response +relationship: regulates GO:0002279 ! mast cell activation involved in immune response + +[Term] +id: GO:0033007 +name: negative regulation of mast cell activation involved in immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response." [GOC:mah] +synonym: "negative regulation of mast cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0033004 ! negative regulation of mast cell activation +is_a: GO:0033006 ! regulation of mast cell activation involved in immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002279 ! mast cell activation involved in immune response +relationship: negatively_regulates GO:0002279 ! mast cell activation involved in immune response + +[Term] +id: GO:0033008 +name: positive regulation of mast cell activation involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response." [GOC:mah] +synonym: "positive regulation of mast cell activation during immune response" RELATED [GOC:tb] +is_a: GO:0033005 ! positive regulation of mast cell activation +is_a: GO:0033006 ! regulation of mast cell activation involved in immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002279 ! mast cell activation involved in immune response +relationship: positively_regulates GO:0002279 ! mast cell activation involved in immune response + +[Term] +id: GO:0033009 +name: nucleomorph +namespace: cellular_component +def: "A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively." [PMID:16760254] +xref: Wikipedia:Nucleomorph +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0033010 +name: paranodal junction +namespace: cellular_component +def: "A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath." [PMID:11395001, PMID:14630217] +synonym: "axoglial septate junction" EXACT [MP:0010735] +synonym: "paranodal axoglial junction" EXACT [PMID:18803321] +synonym: "paranodal septate junction" EXACT [MP:0010735] +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0033011 +name: perinuclear theca +namespace: cellular_component +def: "A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins." [PMID:17289678, PMID:8025156] +is_a: GO:0005856 ! cytoskeleton +relationship: part_of GO:0048471 ! perinuclear region of cytoplasm + +[Term] +id: GO:0033012 +name: porosome +namespace: cellular_component +def: "A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles." [PMID:15090256, PMID:16563225] +xref: Wikipedia:Porosome +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0033013 +name: tetrapyrrole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] +synonym: "tetrapyrrole metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0033014 +name: tetrapyrrole biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] +synonym: "tetrapyrrole anabolism" EXACT [] +synonym: "tetrapyrrole biosynthesis" EXACT [] +synonym: "tetrapyrrole formation" EXACT [] +synonym: "tetrapyrrole synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0033015 +name: tetrapyrrole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] +synonym: "tetrapyrrole breakdown" EXACT [] +synonym: "tetrapyrrole catabolism" EXACT [] +synonym: "tetrapyrrole degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0033016 +name: rhoptry membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a rhoptry." [GOC:mah] +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0020008 ! rhoptry + +[Term] +id: GO:0033017 +name: sarcoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the sarcoplasmic reticulum." [GOC:rph] +is_a: GO:0005789 ! endoplasmic reticulum membrane +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0016529 ! sarcoplasmic reticulum + +[Term] +id: GO:0033018 +name: sarcoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the sarcoplasmic reticulum." [GOC:rph] +is_a: GO:0005788 ! endoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0016529 ! sarcoplasmic reticulum +relationship: part_of GO:0016529 ! sarcoplasmic reticulum + +[Term] +id: GO:0033019 +name: 5-hydroxyvalerate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH." [GOC:mlg, PMID:12406764] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033020 +name: cyclopentanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyclopentanol." [GOC:mlg, PMID:12406764] +synonym: "cyclopentanol metabolism" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0033021 +name: cyclopentanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyclopentanol." [GOC:mah, PMID:12406764] +synonym: "cyclopentanol anabolism" EXACT [] +synonym: "cyclopentanol biosynthesis" EXACT [] +synonym: "cyclopentanol formation" EXACT [] +synonym: "cyclopentanol synthesis" EXACT [] +is_a: GO:0033020 ! cyclopentanol metabolic process +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0033022 +name: cyclopentanol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyclopentanol." [GOC:mah, PMID:12406764] +synonym: "cyclopentanol breakdown" EXACT [] +synonym: "cyclopentanol catabolism" EXACT [] +synonym: "cyclopentanol degradation" EXACT [] +is_a: GO:0033020 ! cyclopentanol metabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0033023 +name: mast cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:11292031] +comment: Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus. +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis + +[Term] +id: GO:0033024 +name: mast cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [CL:0000097, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:12360215, PMID:16605130] +synonym: "apoptosis of mast cells" EXACT [] +synonym: "mast cell apoptosis" NARROW [] +is_a: GO:0033028 ! myeloid cell apoptotic process +is_a: GO:0071887 ! leukocyte apoptotic process +relationship: part_of GO:0033023 ! mast cell homeostasis + +[Term] +id: GO:0033025 +name: regulation of mast cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mast cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "regulation of mast cell apoptosis" NARROW [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033024 ! mast cell apoptotic process +relationship: regulates GO:0033024 ! mast cell apoptotic process + +[Term] +id: GO:0033026 +name: negative regulation of mast cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "down regulation of mast cell apoptosis" EXACT [] +synonym: "down-regulation of mast cell apoptosis" EXACT [] +synonym: "downregulation of mast cell apoptosis" EXACT [] +synonym: "inhibition of mast cell apoptosis" NARROW [] +synonym: "negative regulation of mast cell apoptosis" NARROW [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0033025 ! regulation of mast cell apoptotic process +is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process +is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033024 ! mast cell apoptotic process +relationship: negatively_regulates GO:0033024 ! mast cell apoptotic process + +[Term] +id: GO:0033027 +name: positive regulation of mast cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "activation of mast cell apoptosis" NARROW [] +synonym: "positive regulation of mast cell apoptosis" NARROW [] +synonym: "stimulation of mast cell apoptosis" NARROW [] +synonym: "up regulation of mast cell apoptosis" EXACT [] +synonym: "up-regulation of mast cell apoptosis" EXACT [] +synonym: "upregulation of mast cell apoptosis" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0033025 ! regulation of mast cell apoptotic process +is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process +is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033024 ! mast cell apoptotic process +relationship: positively_regulates GO:0033024 ! mast cell apoptotic process + +[Term] +id: GO:0033028 +name: myeloid cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093] +synonym: "apoptosis of myeloid cells" EXACT [] +synonym: "myeloid cell apoptosis" NARROW [] +is_a: GO:0006915 ! apoptotic process + +[Term] +id: GO:0033029 +name: regulation of neutrophil apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "regulation of neutrophil apoptosis" NARROW [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001781 ! neutrophil apoptotic process +relationship: regulates GO:0001781 ! neutrophil apoptotic process + +[Term] +id: GO:0033030 +name: negative regulation of neutrophil apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "down regulation of neutrophil apoptosis" EXACT [] +synonym: "down-regulation of neutrophil apoptosis" EXACT [] +synonym: "downregulation of neutrophil apoptosis" EXACT [] +synonym: "inhibition of neutrophil apoptosis" NARROW [] +synonym: "negative regulation of neutrophil apoptosis" NARROW [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0033029 ! regulation of neutrophil apoptotic process +is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process +is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001781 ! neutrophil apoptotic process +relationship: negatively_regulates GO:0001781 ! neutrophil apoptotic process + +[Term] +id: GO:0033031 +name: positive regulation of neutrophil apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "activation of neutrophil apoptosis" NARROW [] +synonym: "positive regulation of neutrophil apoptosis" NARROW [] +synonym: "stimulation of neutrophil apoptosis" NARROW [] +synonym: "up regulation of neutrophil apoptosis" EXACT [] +synonym: "up-regulation of neutrophil apoptosis" EXACT [] +synonym: "upregulation of neutrophil apoptosis" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0033029 ! regulation of neutrophil apoptotic process +is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process +is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001781 ! neutrophil apoptotic process +relationship: positively_regulates GO:0001781 ! neutrophil apoptotic process + +[Term] +id: GO:0033032 +name: regulation of myeloid cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "regulation of myeloid cell apoptosis" NARROW [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033028 ! myeloid cell apoptotic process +relationship: regulates GO:0033028 ! myeloid cell apoptotic process + +[Term] +id: GO:0033033 +name: negative regulation of myeloid cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "down regulation of myeloid cell apoptosis" EXACT [] +synonym: "down-regulation of myeloid cell apoptosis" EXACT [] +synonym: "downregulation of myeloid cell apoptosis" EXACT [] +synonym: "inhibition of myeloid cell apoptosis" NARROW [] +synonym: "negative regulation of myeloid cell apoptosis" NARROW [] +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +is_a: GO:0043066 ! negative regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033028 ! myeloid cell apoptotic process +relationship: negatively_regulates GO:0033028 ! myeloid cell apoptotic process + +[Term] +id: GO:0033034 +name: positive regulation of myeloid cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] +synonym: "activation of myeloid cell apoptosis" NARROW [] +synonym: "positive regulation of myeloid cell apoptosis" NARROW [] +synonym: "stimulation of myeloid cell apoptosis" NARROW [] +synonym: "up regulation of myeloid cell apoptosis" EXACT [] +synonym: "up-regulation of myeloid cell apoptosis" EXACT [] +synonym: "upregulation of myeloid cell apoptosis" EXACT [] +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +is_a: GO:0043065 ! positive regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033028 ! myeloid cell apoptotic process +relationship: positively_regulates GO:0033028 ! myeloid cell apoptotic process + +[Term] +id: GO:0033036 +name: macromolecule localization +namespace: biological_process +def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah] +subset: goslim_flybase_ribbon +synonym: "macromolecule localisation" EXACT [GOC:mah] +is_a: GO:0051179 ! localization + +[Term] +id: GO:0033037 +name: polysaccharide localization +namespace: biological_process +def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "polysaccharide localisation" EXACT [GOC:mah] +is_a: GO:0033036 ! macromolecule localization + +[Term] +id: GO:0033038 +name: bitter taste receptor activity +namespace: molecular_function +def: "Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste." [GOC:mah] +is_a: GO:0008527 ! taste receptor activity +relationship: part_of GO:0001580 ! detection of chemical stimulus involved in sensory perception of bitter taste + +[Term] +id: GO:0033039 +name: salty taste receptor activity +namespace: molecular_function +def: "Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste." [GOC:mah] +is_a: GO:0008527 ! taste receptor activity +relationship: part_of GO:0001583 ! detection of chemical stimulus involved in sensory perception of salty taste + +[Term] +id: GO:0033040 +name: sour taste receptor activity +namespace: molecular_function +def: "Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste." [GOC:mah] +is_a: GO:0008527 ! taste receptor activity +relationship: part_of GO:0001581 ! detection of chemical stimulus involved in sensory perception of sour taste + +[Term] +id: GO:0033041 +name: sweet taste receptor activity +namespace: molecular_function +def: "Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste." [GOC:mah] +is_a: GO:0008527 ! taste receptor activity +relationship: part_of GO:0001582 ! detection of chemical stimulus involved in sensory perception of sweet taste + +[Term] +id: GO:0033042 +name: umami taste receptor activity +namespace: molecular_function +def: "Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates." [GOC:mah] +is_a: GO:0090681 ! GPCR taste receptor activity +relationship: part_of GO:0046535 ! detection of chemical stimulus involved in sensory perception of umami taste + +[Term] +id: GO:0033043 +name: regulation of organelle organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] +subset: goslim_yeast +synonym: "regulation of organelle organisation" EXACT [GOC:mah] +synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006996 ! organelle organization +relationship: regulates GO:0006996 ! organelle organization + +[Term] +id: GO:0033044 +name: regulation of chromosome organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] +synonym: "regulation of chromosome organisation" EXACT [GOC:mah] +synonym: "regulation of chromosome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051276 ! chromosome organization +relationship: regulates GO:0051276 ! chromosome organization + +[Term] +id: GO:0033045 +name: regulation of sister chromatid segregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0051983 ! regulation of chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000819 ! sister chromatid segregation +relationship: regulates GO:0000819 ! sister chromatid segregation + +[Term] +id: GO:0033046 +name: negative regulation of sister chromatid segregation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0033045 ! regulation of sister chromatid segregation +is_a: GO:0051985 ! negative regulation of chromosome segregation +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000819 ! sister chromatid segregation +relationship: negatively_regulates GO:0000819 ! sister chromatid segregation + +[Term] +id: GO:0033047 +name: regulation of mitotic sister chromatid segregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:0033045 ! regulation of sister chromatid segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000070 ! mitotic sister chromatid segregation +relationship: regulates GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0033048 +name: negative regulation of mitotic sister chromatid segregation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] +is_a: GO:0033046 ! negative regulation of sister chromatid segregation +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0045839 ! negative regulation of mitotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation +relationship: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0033049 +name: clavulanic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid." [GOC:mah] +synonym: "clavulanic acid metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0033050 +name: clavulanic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid." [GOC:mah] +synonym: "clavulanic acid anabolism" EXACT [] +synonym: "clavulanic acid biosynthesis" EXACT [] +synonym: "clavulanic acid formation" EXACT [] +synonym: "clavulanic acid synthesis" EXACT [] +xref: Wikipedia:Clavulanic_acid +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0033049 ! clavulanic acid metabolic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0033051 +name: aminophosphonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group." [GOC:mah, http://pages.unibas.ch/mdpi/ecsoc/a0045/a0045.htm, KEGG:map00440] +synonym: "aminophosphonate metabolism" EXACT [] +is_a: GO:0019634 ! organic phosphonate metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0033052 +name: cyanoamino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group." [GOC:mah, PMID:11575729] +synonym: "cyanoamino acid metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0033053 +name: D-glutamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid." [GOC:jsg, GOC:mah] +synonym: "D-glutamine metabolism" EXACT [] +is_a: GO:0006541 ! glutamine metabolic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0033054 +name: D-glutamate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid." [GOC:jsg, GOC:mah] +synonym: "D-glutamate metabolism" EXACT [] +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0033055 +name: D-arginine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid." [GOC:jsg, GOC:mah] +synonym: "D-arginine metabolism" EXACT [] +is_a: GO:0006525 ! arginine metabolic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0033056 +name: D-ornithine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid." [GOC:jsg, GOC:mah] +synonym: "D-ornithine metabolism" EXACT [] +is_a: GO:0006591 ! ornithine metabolic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0033058 +name: directional locomotion +namespace: biological_process +def: "Self-propelled movement of a cell or organism from one location to another along an axis." [GOC:mtg_MIT_16mar07] +is_a: GO:0040011 ! locomotion + +[Term] +id: GO:0033059 +name: cellular pigmentation +namespace: biological_process +def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07] +is_a: GO:0009987 ! cellular process +is_a: GO:0043473 ! pigmentation + +[Term] +id: GO:0033060 +name: ocellus pigmentation +namespace: biological_process +def: "The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates." [GOC:mtg_MIT_16mar07] +is_a: GO:0043473 ! pigmentation + +[Term] +id: GO:0033061 +name: DNA recombinase mediator complex +namespace: cellular_component +def: "A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA." [GOC:elh, GOC:mah, GOC:vw, InterPro:IPR003488, PMID:12912992] +comment: Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly. +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0033062 +name: Rhp55-Rhp57 complex +namespace: cellular_component +def: "A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces)." [GOC:mah, GOC:vw] +synonym: "Rad55-Rad57 complex" EXACT [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033063 +name: Rad51B-Rad51C-Rad51D-XRCC2 complex +namespace: cellular_component +def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] +synonym: "BCDX2 complex" EXACT [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033064 +name: XRCC2-RAD51D complex +namespace: cellular_component +def: "A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast." [GOC:mah, GOC:vw, PMID:16093548] +synonym: "DX2 complex" EXACT [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033065 +name: Rad51C-XRCC3 complex +namespace: cellular_component +def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] +synonym: "CX3 complex" EXACT [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033066 +name: Rad51B-Rad51C complex +namespace: cellular_component +def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] +synonym: "BC complex" EXACT [] +is_a: GO:0033061 ! DNA recombinase mediator complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033067 +name: macrolide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria." [ISBN:0198506732, PMID:17298179] +synonym: "macrolide metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:1901334 ! lactone metabolic process + +[Term] +id: GO:0033068 +name: macrolide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria." [ISBN:0198506732, PMID:17298179] +synonym: "macrolide anabolism" EXACT [] +synonym: "macrolide biosynthesis" EXACT [] +synonym: "macrolide formation" EXACT [] +synonym: "macrolide synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0033067 ! macrolide metabolic process +is_a: GO:1901336 ! lactone biosynthetic process + +[Term] +id: GO:0033069 +name: ansamycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity." [GOC:mah, http://ww2.icho.edu.pl/cednets/rydzyna/meyer.htm] +synonym: "ansamycin metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0033070 +name: ansamycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity." [GOC:mah, http://ww2.icho.edu.pl/cednets/rydzyna/meyer.htm] +synonym: "ansamycin anabolism" EXACT [] +synonym: "ansamycin biosynthesis" EXACT [] +synonym: "ansamycin formation" EXACT [] +synonym: "ansamycin synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0033069 ! ansamycin metabolic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0033071 +name: vancomycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria." [GOC:mah] +synonym: "vancomycin metabolism" EXACT [] +is_a: GO:0030650 ! peptide antibiotic metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0033072 +name: vancomycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria." [GOC:mah] +synonym: "vancomycin anabolism" EXACT [] +synonym: "vancomycin biosynthesis" EXACT [] +synonym: "vancomycin formation" EXACT [] +synonym: "vancomycin synthesis" EXACT [] +is_a: GO:0019184 ! nonribosomal peptide biosynthetic process +is_a: GO:0030651 ! peptide antibiotic biosynthetic process +is_a: GO:0033071 ! vancomycin metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0033073 +name: pinene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane." [GOC:mah, PMID:12623076] +synonym: "pinene metabolism" EXACT [] +is_a: GO:0043692 ! monoterpene metabolic process + +[Term] +id: GO:0033074 +name: pinene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane." [GOC:mah, PMID:11452597] +synonym: "pinene breakdown" EXACT [] +synonym: "pinene catabolism" EXACT [] +synonym: "pinene degradation" EXACT [] +is_a: GO:0033073 ! pinene metabolic process +is_a: GO:0043694 ! monoterpene catabolic process + +[Term] +id: GO:0033075 +name: isoquinoline alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin." [GOC:mah, http://www.life.uiuc.edu/ib/425/lecture32.html] +synonym: "ipecac alkaloid biosynthesis" RELATED [] +synonym: "isoquinoline alkaloid anabolism" EXACT [] +synonym: "isoquinoline alkaloid biosynthesis" EXACT [] +synonym: "isoquinoline alkaloid formation" EXACT [] +synonym: "isoquinoline alkaloid synthesis" EXACT [] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0033076 +name: isoquinoline alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin." [GOC:mah, http://www.life.uiuc.edu/ib/425/lecture32.html] +synonym: "ipecac alkaloid metabolism" RELATED [] +synonym: "isoquinoline alkaloid metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0033077 +name: T cell differentiation in thymus +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T cell development in thymus" RELATED [GOC:add] +synonym: "thymic T cell differentiation" EXACT [] +synonym: "thymocyte cell differentiation" EXACT [] +synonym: "thymocyte differentiation" EXACT [] +is_a: GO:0030217 ! T cell differentiation + +[Term] +id: GO:0033078 +name: extrathymic T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "extrathymic T cell development" RELATED [GOC:add] +is_a: GO:0030217 ! T cell differentiation + +[Term] +id: GO:0033079 +name: immature T cell proliferation +namespace: biological_process +def: "The expansion of an immature T cell population by cell division." [GOC:add, ISBN:0781735149] +is_a: GO:0042098 ! T cell proliferation + +[Term] +id: GO:0033080 +name: immature T cell proliferation in thymus +namespace: biological_process +def: "The expansion of an immature T cell population by cell division in the thymus." [GOC:add, ISBN:0781735149] +synonym: "thymic T cell proliferation" EXACT [] +synonym: "thymocyte cell proliferation" EXACT [] +synonym: "thymocyte proliferation" EXACT [] +is_a: GO:0033079 ! immature T cell proliferation +relationship: part_of GO:0033077 ! T cell differentiation in thymus + +[Term] +id: GO:0033081 +name: regulation of T cell differentiation in thymus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of T cell development in thymus" RELATED [GOC:add] +synonym: "regulation of thymic T cell differentiation" EXACT [] +synonym: "regulation of thymocyte cell differentiation" EXACT [] +synonym: "regulation of thymocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033077 ! T cell differentiation in thymus +relationship: regulates GO:0033077 ! T cell differentiation in thymus + +[Term] +id: GO:0033082 +name: regulation of extrathymic T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of extrathymic T cell development" RELATED [GOC:add] +is_a: GO:0045580 ! regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033078 ! extrathymic T cell differentiation +relationship: regulates GO:0033078 ! extrathymic T cell differentiation + +[Term] +id: GO:0033083 +name: regulation of immature T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] +is_a: GO:0042129 ! regulation of T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033079 ! immature T cell proliferation +relationship: regulates GO:0033079 ! immature T cell proliferation + +[Term] +id: GO:0033084 +name: regulation of immature T cell proliferation in thymus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of thymic T cell proliferation" EXACT [] +synonym: "regulation of thymocyte cell proliferation" EXACT [] +synonym: "regulation of thymocyte proliferation" EXACT [] +is_a: GO:0033081 ! regulation of T cell differentiation in thymus +is_a: GO:0033083 ! regulation of immature T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033080 ! immature T cell proliferation in thymus +relationship: regulates GO:0033080 ! immature T cell proliferation in thymus + +[Term] +id: GO:0033085 +name: negative regulation of T cell differentiation in thymus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "negative regulation of T cell development in thymus" RELATED [GOC:add] +synonym: "negative regulation of thymic T cell differentiation" EXACT [] +synonym: "negative regulation of thymocyte cell differentiation" EXACT [] +synonym: "negative regulation of thymocyte differentiation" EXACT [] +is_a: GO:0033081 ! regulation of T cell differentiation in thymus +is_a: GO:0045581 ! negative regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033077 ! T cell differentiation in thymus +relationship: negatively_regulates GO:0033077 ! T cell differentiation in thymus + +[Term] +id: GO:0033086 +name: negative regulation of extrathymic T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "negative regulation of extrathymic T cell development" RELATED [GOC:add] +is_a: GO:0033082 ! regulation of extrathymic T cell differentiation +is_a: GO:0045581 ! negative regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033078 ! extrathymic T cell differentiation +relationship: negatively_regulates GO:0033078 ! extrathymic T cell differentiation + +[Term] +id: GO:0033087 +name: negative regulation of immature T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] +is_a: GO:0033083 ! regulation of immature T cell proliferation +is_a: GO:0042130 ! negative regulation of T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033079 ! immature T cell proliferation +relationship: negatively_regulates GO:0033079 ! immature T cell proliferation + +[Term] +id: GO:0033088 +name: negative regulation of immature T cell proliferation in thymus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] +synonym: "negative regulation of thymic T cell proliferation" EXACT [] +synonym: "negative regulation of thymocyte cell proliferation" EXACT [] +synonym: "negative regulation of thymocyte proliferation" EXACT [] +is_a: GO:0033084 ! regulation of immature T cell proliferation in thymus +is_a: GO:0033085 ! negative regulation of T cell differentiation in thymus +is_a: GO:0033087 ! negative regulation of immature T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033080 ! immature T cell proliferation in thymus +relationship: negatively_regulates GO:0033080 ! immature T cell proliferation in thymus + +[Term] +id: GO:0033089 +name: positive regulation of T cell differentiation in thymus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "positive regulation of T cell development in thymus" RELATED [GOC:add] +synonym: "positive regulation of thymic T cell differentiation" EXACT [] +synonym: "positive regulation of thymocyte cell differentiation" EXACT [] +synonym: "positive regulation of thymocyte differentiation" EXACT [] +is_a: GO:0033081 ! regulation of T cell differentiation in thymus +is_a: GO:0045582 ! positive regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033077 ! T cell differentiation in thymus +relationship: positively_regulates GO:0033077 ! T cell differentiation in thymus + +[Term] +id: GO:0033090 +name: positive regulation of extrathymic T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "positive regulation of extrathymic T cell development" RELATED [GOC:add] +is_a: GO:0033082 ! regulation of extrathymic T cell differentiation +is_a: GO:0045582 ! positive regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033078 ! extrathymic T cell differentiation +relationship: positively_regulates GO:0033078 ! extrathymic T cell differentiation + +[Term] +id: GO:0033091 +name: positive regulation of immature T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] +is_a: GO:0033083 ! regulation of immature T cell proliferation +is_a: GO:0042102 ! positive regulation of T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033079 ! immature T cell proliferation +relationship: positively_regulates GO:0033079 ! immature T cell proliferation + +[Term] +id: GO:0033092 +name: positive regulation of immature T cell proliferation in thymus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] +synonym: "positive regulation of thymic T cell proliferation" EXACT [] +synonym: "positive regulation of thymocyte cell proliferation" EXACT [] +synonym: "positive regulation of thymocyte proliferation" EXACT [] +is_a: GO:0033084 ! regulation of immature T cell proliferation in thymus +is_a: GO:0033089 ! positive regulation of T cell differentiation in thymus +is_a: GO:0033091 ! positive regulation of immature T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033080 ! immature T cell proliferation in thymus +relationship: positively_regulates GO:0033080 ! immature T cell proliferation in thymus + +[Term] +id: GO:0033093 +name: Weibel-Palade body +namespace: cellular_component +def: "A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses." [PMID:11935287, PMID:16087708] +xref: Wikipedia:Weibel-Palade_body +is_a: GO:0030136 ! clathrin-coated vesicle +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0033094 +name: butane-1,4-diamine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O." [EC:2.6.1.82, GOC:mlg, RHEA:12268] +synonym: "PAT activity" RELATED [] +synonym: "putrescine aminotransferase activity" BROAD [EC:2.6.1.82] +synonym: "putrescine transaminase activity" BROAD [] +synonym: "putrescine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.82] +synonym: "putrescine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.82] +synonym: "putrescine:alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.82] +synonym: "YgjG" RELATED [EC:2.6.1.82] +xref: EC:2.6.1.82 +xref: MetaCyc:2.6.1.82-RXN +xref: RHEA:12268 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0033095 +name: aleurone grain +namespace: cellular_component +def: "A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes." [PMID:22452734, Wikipedia:Aleurone] +synonym: "aleurone body" EXACT [] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0033096 +name: amyloplast envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] +is_a: GO:0009526 ! plastid envelope +relationship: part_of GO:0009501 ! amyloplast + +[Term] +id: GO:0033097 +name: amyloplast membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope." [GOC:ecd] +is_a: GO:0042170 ! plastid membrane +relationship: part_of GO:0033096 ! amyloplast envelope + +[Term] +id: GO:0033098 +name: amyloplast inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma." [GOC:ecd] +is_a: GO:0009528 ! plastid inner membrane +is_a: GO:0033097 ! amyloplast membrane + +[Term] +id: GO:0033099 +name: attachment organelle +namespace: cellular_component +def: "A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division." [PMID:11325545, PMID:12003948] +subset: goslim_pir +is_a: GO:0043231 ! intracellular membrane-bounded organelle + +[Term] +id: GO:0033100 +name: NuA3 histone acetyltransferase complex +namespace: cellular_component +def: "A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p." [PMID:10817755, PMID:17157260] +is_a: GO:0070775 ! H3 histone acetyltransferase complex + +[Term] +id: GO:0033101 +name: cellular bud membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a cellular bud." [GOC:mah] +synonym: "cellular bud plasma membrane" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005933 ! cellular bud + +[Term] +id: GO:0033102 +name: acidocalcisome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an acidocalcisome." [GOC:ecd, PMID:11378195] +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0020022 ! acidocalcisome + +[Term] +id: GO:0033103 +name: protein secretion by the type VI secretion system +namespace: biological_process +def: "The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence." [GOC:mlg, PMID:16432199, PMID:16763151] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type VI protein secretion system complex ; GO:0033104'. +synonym: "protein secretion by the T6SS" EXACT [] +synonym: "protein secretion by the type VI protein secretion system" EXACT [] +synonym: "type VI protein secretion system" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0033104 +name: type VI protein secretion system complex +namespace: cellular_component +def: "A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence." [GOC:mlg, PMID:16432199, PMID:16763151] +synonym: "T6SS complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0033105 +name: chlorosome envelope +namespace: cellular_component +def: "The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome." [PMID:14507718, PMID:14729689, PMID:17303128] +comment: Note that the chlorosome envelope is not a single or double lipid bilayer, so this term is not a child of 'organelle membrane ; GO:0031090' or 'organelle envelope ; GO:0031967'. +synonym: "chlorosome membrane" EXACT [] +is_a: GO:0034646 ! organelle-enclosing lipid monolayer +relationship: part_of GO:0046858 ! chlorosome + +[Term] +id: GO:0033106 +name: cis-Golgi network membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network." [GOC:mah] +synonym: "cis Golgi network membrane" EXACT [] +synonym: "Golgi cis face membrane" RELATED [] +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005801 ! cis-Golgi network + +[Term] +id: GO:0033107 +name: Cvt vesicle +namespace: cellular_component +def: "A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p)." [GOC:rb, PMID:15138258] +synonym: "cytoplasm to vacuole targeting vesicle" EXACT [] +synonym: "cytoplasm-to-vacuole targeting vesicle" EXACT [] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0033108 +name: mitochondrial respiratory chain complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex." [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0033110 +name: Cvt vesicle membrane +namespace: cellular_component +def: "Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway." [GOC:ecd, PMID:20065092] +synonym: "cytoplasm to vacuole targeting vesicle membrane" EXACT [] +synonym: "cytoplasm-to-vacuole targeting vesicle membrane" EXACT [] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +relationship: part_of GO:0033107 ! Cvt vesicle + +[Term] +id: GO:0033111 +name: attachment organelle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane." [GOC:ecd] +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098589 ! membrane region +relationship: part_of GO:0033099 ! attachment organelle + +[Term] +id: GO:0033112 +name: cyanelle envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] +is_a: GO:0009526 ! plastid envelope +relationship: part_of GO:0009842 ! cyanelle + +[Term] +id: GO:0033113 +name: cyanelle membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope." [GOC:ecd] +is_a: GO:0042170 ! plastid membrane +relationship: part_of GO:0033112 ! cyanelle envelope + +[Term] +id: GO:0033114 +name: cyanelle thylakoid lumen +namespace: cellular_component +def: "The volume enclosed by a cyanelle thylakoid membrane." [GOC:mah] +is_a: GO:0031978 ! plastid thylakoid lumen +relationship: part_of GO:0009843 ! cyanelle thylakoid + +[Term] +id: GO:0033115 +name: cyanelle thylakoid membrane +namespace: cellular_component +def: "The lipid bilayer membrane of any thylakoid within a cyanelle." [GOC:mah] +is_a: GO:0055035 ! plastid thylakoid membrane +relationship: part_of GO:0009843 ! cyanelle thylakoid + +[Term] +id: GO:0033116 +name: endoplasmic reticulum-Golgi intermediate compartment membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system." [GOC:mah, GOC:pr, PMID:16723730] +synonym: "ER-Golgi intermediate compartment membrane" EXACT [] +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005793 ! endoplasmic reticulum-Golgi intermediate compartment + +[Term] +id: GO:0033117 +name: esterosome +namespace: cellular_component +def: "A vesicle filled with crystalline protein that shows sequence similarities with various esterases." [GOC:ecd, PMID:2307702] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0033118 +name: esterosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes." [GOC:ecd, PMID:2307702] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0033117 ! esterosome + +[Term] +id: GO:0033119 +name: negative regulation of RNA splicing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing." [GOC:mah] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0043484 ! regulation of RNA splicing +is_a: GO:0051253 ! negative regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008380 ! RNA splicing +relationship: negatively_regulates GO:0008380 ! RNA splicing + +[Term] +id: GO:0033120 +name: positive regulation of RNA splicing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA splicing." [GOC:mah] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0043484 ! regulation of RNA splicing +is_a: GO:0051254 ! positive regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008380 ! RNA splicing +relationship: positively_regulates GO:0008380 ! RNA splicing + +[Term] +id: GO:0033121 +name: regulation of purine nucleotide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] +synonym: "regulation of purine nucleotide breakdown" EXACT [] +synonym: "regulation of purine nucleotide catabolism" EXACT [] +synonym: "regulation of purine nucleotide degradation" EXACT [] +is_a: GO:0030811 ! regulation of nucleotide catabolic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006195 ! purine nucleotide catabolic process +relationship: regulates GO:0006195 ! purine nucleotide catabolic process + +[Term] +id: GO:0033122 +name: negative regulation of purine nucleotide catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] +synonym: "negative regulation of purine nucleotide breakdown" EXACT [] +synonym: "negative regulation of purine nucleotide catabolism" EXACT [] +synonym: "negative regulation of purine nucleotide degradation" EXACT [] +is_a: GO:0030812 ! negative regulation of nucleotide catabolic process +is_a: GO:0033121 ! regulation of purine nucleotide catabolic process +is_a: GO:1900543 ! negative regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006195 ! purine nucleotide catabolic process +relationship: negatively_regulates GO:0006195 ! purine nucleotide catabolic process + +[Term] +id: GO:0033123 +name: positive regulation of purine nucleotide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] +synonym: "positive regulation of purine nucleotide breakdown" EXACT [] +synonym: "positive regulation of purine nucleotide catabolism" EXACT [] +synonym: "positive regulation of purine nucleotide degradation" EXACT [] +is_a: GO:0030813 ! positive regulation of nucleotide catabolic process +is_a: GO:0033121 ! regulation of purine nucleotide catabolic process +is_a: GO:1900544 ! positive regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006195 ! purine nucleotide catabolic process +relationship: positively_regulates GO:0006195 ! purine nucleotide catabolic process + +[Term] +id: GO:0033124 +name: obsolete regulation of GTP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "regulation of GTP breakdown" EXACT [] +synonym: "regulation of GTP catabolism" EXACT [] +synonym: "regulation of GTP degradation" EXACT [] +is_obsolete: true +consider: GO:0043087 + +[Term] +id: GO:0033125 +name: obsolete negative regulation of GTP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "negative regulation of GTP breakdown" EXACT [] +synonym: "negative regulation of GTP catabolism" EXACT [] +synonym: "negative regulation of GTP degradation" EXACT [] +is_obsolete: true +consider: GO:0034260 + +[Term] +id: GO:0033126 +name: obsolete positive regulation of GTP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "positive regulation of GTP breakdown" EXACT [] +synonym: "positive regulation of GTP catabolism" EXACT [] +synonym: "positive regulation of GTP degradation" EXACT [] +is_obsolete: true +consider: GO:0043547 + +[Term] +id: GO:0033127 +name: regulation of histone phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0031056 ! regulation of histone modification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016572 ! histone phosphorylation +relationship: regulates GO:0016572 ! histone phosphorylation + +[Term] +id: GO:0033128 +name: negative regulation of histone phosphorylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0033127 ! regulation of histone phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016572 ! histone phosphorylation +relationship: negatively_regulates GO:0016572 ! histone phosphorylation + +[Term] +id: GO:0033129 +name: positive regulation of histone phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0033127 ! regulation of histone phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016572 ! histone phosphorylation +relationship: positively_regulates GO:0016572 ! histone phosphorylation + +[Term] +id: GO:0033130 +name: acetylcholine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an acetylcholine receptor." [GOC:mah] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0033131 +name: regulation of glucokinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule." [GOC:mah] +synonym: "glucokinase regulator" NARROW [] +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:1903299 ! regulation of hexokinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004340 ! glucokinase activity +relationship: regulates GO:0004340 ! glucokinase activity + +[Term] +id: GO:0033132 +name: negative regulation of glucokinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule." [GOC:mah] +synonym: "down regulation of glucokinase activity" EXACT [] +synonym: "down-regulation of glucokinase activity" EXACT [] +synonym: "downregulation of glucokinase activity" EXACT [] +synonym: "glucokinase inhibitor" NARROW [] +synonym: "inhibition of glucokinase activity" NARROW [] +is_a: GO:0033131 ! regulation of glucokinase activity +is_a: GO:1903300 ! negative regulation of hexokinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004340 ! glucokinase activity +relationship: negatively_regulates GO:0004340 ! glucokinase activity + +[Term] +id: GO:0033133 +name: positive regulation of glucokinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule." [GOC:mah] +synonym: "glucokinase activator" NARROW [] +synonym: "stimulation of glucokinase activity" NARROW [] +synonym: "up regulation of glucokinase activity" EXACT [] +synonym: "up-regulation of glucokinase activity" EXACT [] +synonym: "upregulation of glucokinase activity" EXACT [] +is_a: GO:0033131 ! regulation of glucokinase activity +is_a: GO:1903301 ! positive regulation of hexokinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004340 ! glucokinase activity +relationship: positively_regulates GO:0004340 ! glucokinase activity + +[Term] +id: GO:0033134 +name: ubiquitin activating enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin activating enzyme, any of the E1 proteins." [GOC:mah] +is_a: GO:0044388 ! small protein activating enzyme binding + +[Term] +id: GO:0033135 +name: regulation of peptidyl-serine phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] +is_a: GO:0001932 ! regulation of protein phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018105 ! peptidyl-serine phosphorylation +relationship: regulates GO:0018105 ! peptidyl-serine phosphorylation + +[Term] +id: GO:0033137 +name: negative regulation of peptidyl-serine phosphorylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018105 ! peptidyl-serine phosphorylation +relationship: negatively_regulates GO:0018105 ! peptidyl-serine phosphorylation + +[Term] +id: GO:0033138 +name: positive regulation of peptidyl-serine phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018105 ! peptidyl-serine phosphorylation +relationship: positively_regulates GO:0018105 ! peptidyl-serine phosphorylation + +[Term] +id: GO:0033139 +name: regulation of peptidyl-serine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:1903261 +def: "Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] +synonym: "regulation of serine phosphorylation of STAT3 protein" NARROW [] +is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation +is_a: GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042501 ! serine phosphorylation of STAT protein +relationship: regulates GO:0042501 ! serine phosphorylation of STAT protein +created_by: mr +creation_date: 2014-08-06T21:22:57Z + +[Term] +id: GO:0033140 +name: negative regulation of peptidyl-serine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:1903262 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] +synonym: "down regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "down-regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "downregulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "inhibition of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "negative regulation of serine phosphorylation of STAT3 protein" NARROW [] +is_a: GO:0033137 ! negative regulation of peptidyl-serine phosphorylation +is_a: GO:0033139 ! regulation of peptidyl-serine phosphorylation of STAT protein +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042501 ! serine phosphorylation of STAT protein +relationship: negatively_regulates GO:0042501 ! serine phosphorylation of STAT protein + +[Term] +id: GO:0033141 +name: positive regulation of peptidyl-serine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:1903263 +def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] +synonym: "activation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "positive regulation of serine phosphorylation of STAT3 protein" NARROW [] +synonym: "up regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "up-regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +synonym: "upregulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] +is_a: GO:0033138 ! positive regulation of peptidyl-serine phosphorylation +is_a: GO:0033139 ! regulation of peptidyl-serine phosphorylation of STAT protein +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042501 ! serine phosphorylation of STAT protein +relationship: positively_regulates GO:0042501 ! serine phosphorylation of STAT protein + +[Term] +id: GO:0033142 +name: progesterone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a progesterone receptor." [GOC:mah] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0035258 ! steroid hormone receptor binding + +[Term] +id: GO:0033143 +name: regulation of intracellular steroid hormone receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway." [GOC:mah] +synonym: "regulation of steroid hormone receptor signaling pathway" BROAD [GOC:bf] +synonym: "regulation of steroid hormone receptor signalling pathway" BROAD [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway +relationship: regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0033144 +name: negative regulation of intracellular steroid hormone receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway." [GOC:mah] +synonym: "negative regulation of steroid hormone receptor signaling pathway" BROAD [GOC:bf] +synonym: "negative regulation of steroid hormone receptor signalling pathway" BROAD [GOC:bf] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway +relationship: negatively_regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0033145 +name: positive regulation of intracellular steroid hormone receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway." [GOC:mah] +synonym: "positive regulation of steroid hormone receptor signaling pathway" BROAD [GOC:bf] +synonym: "positive regulation of steroid hormone receptor signalling pathway" BROAD [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway +relationship: positively_regulates GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0033146 +name: regulation of intracellular estrogen receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway." [GOC:mah] +synonym: "regulation of estrogen receptor signaling pathway" BROAD [GOC:bf] +synonym: "regulation of estrogen receptor signalling pathway" EXACT [] +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030520 ! intracellular estrogen receptor signaling pathway +relationship: regulates GO:0030520 ! intracellular estrogen receptor signaling pathway + +[Term] +id: GO:0033147 +name: negative regulation of intracellular estrogen receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway." [GOC:mah] +synonym: "negative regulation of estrogen receptor signaling pathway" BROAD [GOC:bf] +synonym: "negative regulation of estrogen receptor signalling pathway" EXACT [] +is_a: GO:0033144 ! negative regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:0033146 ! regulation of intracellular estrogen receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030520 ! intracellular estrogen receptor signaling pathway +relationship: negatively_regulates GO:0030520 ! intracellular estrogen receptor signaling pathway + +[Term] +id: GO:0033148 +name: positive regulation of intracellular estrogen receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway." [GOC:mah] +synonym: "positive regulation of estrogen receptor signaling pathway" BROAD [GOC:bf] +synonym: "positive regulation of estrogen receptor signalling pathway" BROAD [] +is_a: GO:0033145 ! positive regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:0033146 ! regulation of intracellular estrogen receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030520 ! intracellular estrogen receptor signaling pathway +relationship: positively_regulates GO:0030520 ! intracellular estrogen receptor signaling pathway + +[Term] +id: GO:0033149 +name: FFAT motif binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family." [PMID:12727870, PMID:15455074, PMID:16004875] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0033150 +name: cytoskeletal calyx +namespace: cellular_component +def: "A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins." [PMID:12243744, PMID:9184090] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0033011 ! perinuclear theca + +[Term] +id: GO:0033151 +name: V(D)J recombination +namespace: biological_process +def: "The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)." [GOC:add, ISBN:0781700221, ISBN:0781735149] +synonym: "V(D)J joining" EXACT [] +synonym: "V-D-J joining" EXACT [] +synonym: "V-D-J recombination" EXACT [] +synonym: "V-J joining" EXACT [] +synonym: "V-J recombination" EXACT [] +xref: Wikipedia:V(D)J_recombination +is_a: GO:0002562 ! somatic diversification of immune receptors via germline recombination within a single locus + +[Term] +id: GO:0033152 +name: immunoglobulin V(D)J recombination +namespace: biological_process +def: "The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined." [GOC:add, ISBN:0781735149] +synonym: "immunoglobulin V(D)J joining" EXACT [GOC:add] +synonym: "immunoglobulin V-D-J joining" NARROW [GOC:add] +synonym: "immunoglobulin V-D-J recombination" NARROW [GOC:add] +synonym: "immunoglobulin V-J joining" NARROW [GOC:add] +synonym: "immunoglobulin V-J recombination" NARROW [GOC:add] +is_a: GO:0016447 ! somatic recombination of immunoglobulin gene segments +is_a: GO:0033151 ! V(D)J recombination + +[Term] +id: GO:0033153 +name: T cell receptor V(D)J recombination +namespace: biological_process +def: "The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)." [GOC:add, ISBN:0781700221] +synonym: "T cell receptor V(D)J joining" EXACT [GOC:add] +synonym: "T cell receptor V-D-J joining" NARROW [GOC:add] +synonym: "T cell receptor V-D-J recombination" NARROW [GOC:add] +synonym: "T cell receptor V-J joining" NARROW [GOC:add] +synonym: "T cell receptor V-J recombination" NARROW [GOC:add] +synonym: "T-cell receptor V(D)J recombination" EXACT [GOC:add] +synonym: "TCR V(D)J recombination" EXACT [GOC:add] +is_a: GO:0002681 ! somatic recombination of T cell receptor gene segments +is_a: GO:0033151 ! V(D)J recombination + +[Term] +id: GO:0033154 +name: ATPase-coupled oligogalacturonide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in)." [GOC:mlg] +synonym: "ATP-dependent oligogalacturonide transmembrane transporter activity" EXACT [] +synonym: "oligogalacturonide transporting ATPase activity" RELATED [] +synonym: "oligogalacturonide-transporting ATPase activity" EXACT [] +is_a: GO:0015422 ! ATPase-coupled oligosaccharide transmembrane transporter activity +is_a: GO:0033155 ! oligogalacturonide transmembrane transporter activity + +[Term] +id: GO:0033155 +name: oligogalacturonide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oligogalacturonide from one side of a membrane to the other." [GOC:mlg] +is_a: GO:0015157 ! oligosaccharide transmembrane transporter activity +relationship: part_of GO:0033156 ! oligogalacturonide transport + +[Term] +id: GO:0033156 +name: oligogalacturonide transport +namespace: biological_process +def: "The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mlg] +is_a: GO:0015772 ! oligosaccharide transport + +[Term] +id: GO:0033157 +name: regulation of intracellular protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006886 ! intracellular protein transport +relationship: regulates GO:0006886 ! intracellular protein transport + +[Term] +id: GO:0033158 +name: obsolete regulation of protein import into nucleus, translocation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:mah] +comment: This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used. +synonym: "regulation of protein import into cell nucleus, translocation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0033159 +name: obsolete negative regulation of protein import into nucleus, translocation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:mah] +comment: This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used. +synonym: "negative regulation of protein import into cell nucleus, translocation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0033160 +name: obsolete positive regulation of protein import into nucleus, translocation +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:mah] +comment: This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used. +synonym: "positive regulation of protein import into cell nucleus, translocation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0033161 +name: mitogen-activated protein kinase kinase kinase kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase." [GOC:mah] +synonym: "MAPKKKK binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0033162 +name: melanosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a melanosome." [GOC:mah] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0090741 ! pigment granule membrane +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0042470 ! melanosome +relationship: part_of GO:0045009 ! chitosome + +[Term] +id: GO:0033163 +name: microneme membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a microneme." [GOC:mah] +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0020009 ! microneme + +[Term] +id: GO:0033164 +name: glycolipid 6-alpha-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage." [EC:2.4.1.232, GOC:mcc, PMID:16878994] +synonym: "GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] +synonym: "GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] +synonym: "GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] +synonym: "initiation-specific alpha-1,6-mannosyltransferase activity" EXACT [EC:2.4.1.232] +xref: EC:2.4.1.232 +xref: MetaCyc:2.4.1.232-RXN +is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity +is_a: GO:0004376 ! glycolipid mannosyltransferase activity + +[Term] +id: GO:0033165 +name: interphotoreceptor matrix +namespace: cellular_component +def: "A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance." [http://www.glycoforum.gr.jp/science/hyaluronan/HA17/HA17E.html, PMID:1862095, PMID:2194288] +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0033166 +name: hyaline layer +namespace: cellular_component +def: "A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms." [http://worms.zoology.wisc.edu/urchins/SUgast_ECM3.html, PMID:1721506, PMID:9473317] +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0033167 +name: ARC complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA." [GOC:vw, PMID:17310250] +synonym: "argonaute siRNA chaperone complex" EXACT [] +is_a: GO:0031332 ! RNAi effector complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033168 +name: conversion of ds siRNA to ss siRNA involved in RNA interference +namespace: biological_process +def: "The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference." [GOC:mah, PMID:17310250] +synonym: "RNA interference, conversion of ds siRNA to ss siRNA" EXACT [GOC:mah] +is_a: GO:0036404 ! conversion of ds siRNA to ss siRNA +intersection_of: GO:0036404 ! conversion of ds siRNA to ss siRNA +intersection_of: part_of GO:0016246 ! RNA interference +relationship: part_of GO:0030422 ! production of siRNA involved in RNA interference + +[Term] +id: GO:0033169 +name: histone H3-K9 demethylation +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone." [GOC:mah] +is_a: GO:0070076 ! histone lysine demethylation + +[Term] +id: GO:0033170 +name: protein-DNA loading ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protein complex onto a DNA molecule." [GOC:mah, GOC:vw] +synonym: "DNA-protein loading ATPase activity" EXACT [GOC:mah] +is_a: GO:0008094 ! DNA-dependent ATPase activity + +[Term] +id: GO:0033171 +name: obsolete nucleoprotein filament-forming ATPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament." [GOC:mah, GOC:vw] +comment: This term was made obsolete because nucleoprotein filament formation does not require ATP hydrolysis, so the term is misleading. +synonym: "nucleoprotein filament-forming ATPase activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0033172 +name: gas vesicle shell +namespace: cellular_component +def: "The proteinaceous structure surrounding a gas vesicle." [GOC:ecd] +synonym: "gas vesicle membrane" RELATED [] +synonym: "gas vesicle wall" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031411 ! gas vesicle + +[Term] +id: GO:0033173 +name: calcineurin-NFAT signaling cascade +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+)." [GOC:lm, GOC:mah, PMID:12975316, PMID:15928679] +synonym: "calcineurin-NFAT signaling pathway" RELATED [GOC:bf] +synonym: "calcineurin-NFAT signalling pathway" RELATED [] +is_a: GO:0048016 ! inositol phosphate-mediated signaling +is_a: GO:0097720 ! calcineurin-mediated signaling + +[Term] +id: GO:0033174 +name: chloroplast proton-transporting ATP synthase complex, catalytic core CF(1) +namespace: cellular_component +def: "The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits." [GOC:mah, GOC:pj, PMID:11032839] +synonym: "chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1)" EXACT [] +is_a: GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +relationship: part_of GO:0045320 ! chloroplast proton-transporting ATP synthase complex + +[Term] +id: GO:0033175 +name: chloroplast proton-transporting ATP synthase complex, coupling factor CF(o) +namespace: cellular_component +def: "All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins." [GOC:mah] +synonym: "chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)" EXACT [] +synonym: "chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o)" EXACT [] +is_a: GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +relationship: part_of GO:0045320 ! chloroplast proton-transporting ATP synthase complex + +[Term] +id: GO:0033176 +name: proton-transporting V-type ATPase complex +namespace: cellular_component +def: "A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane." [GOC:mah, ISBN:0716743663, PMID:16449553] +synonym: "hydrogen-translocating V-type ATPase complex" EXACT [] +is_a: GO:0016469 ! proton-transporting two-sector ATPase complex + +[Term] +id: GO:0033177 +name: proton-transporting two-sector ATPase complex, proton-transporting domain +namespace: cellular_component +def: "A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins." [GOC:mah, PMID:10838056] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016469 ! proton-transporting two-sector ATPase complex + +[Term] +id: GO:0033178 +name: proton-transporting two-sector ATPase complex, catalytic domain +namespace: cellular_component +def: "A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled." [GOC:mah, PMID:10838056] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016469 ! proton-transporting two-sector ATPase complex + +[Term] +id: GO:0033179 +name: proton-transporting V-type ATPase, V0 domain +namespace: cellular_component +def: "A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring." [GOC:mah, ISBN:0716743663, PMID:16449553] +is_a: GO:0033177 ! proton-transporting two-sector ATPase complex, proton-transporting domain +relationship: part_of GO:0033176 ! proton-transporting V-type ATPase complex + +[Term] +id: GO:0033180 +name: proton-transporting V-type ATPase, V1 domain +namespace: cellular_component +def: "A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A." [GOC:mah, ISBN:0716743663, PMID:16449553] +is_a: GO:0033178 ! proton-transporting two-sector ATPase complex, catalytic domain +relationship: part_of GO:0033176 ! proton-transporting V-type ATPase complex + +[Term] +id: GO:0033181 +name: plasma membrane proton-transporting V-type ATPase complex +namespace: cellular_component +def: "A proton-transporting two-sector ATPase complex found in the plasma membrane." [GOC:mah] +synonym: "plasma membrane hydrogen ion-transporting ATPase" EXACT [] +is_a: GO:0033176 ! proton-transporting V-type ATPase complex +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0033176 ! proton-transporting V-type ATPase complex +intersection_of: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0033182 +name: regulation of histone ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein." [GOC:mah] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0031396 ! regulation of protein ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016574 ! histone ubiquitination +relationship: regulates GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0033183 +name: negative regulation of histone ubiquitination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein." [GOC:mah] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0031397 ! negative regulation of protein ubiquitination +is_a: GO:0033182 ! regulation of histone ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016574 ! histone ubiquitination +relationship: negatively_regulates GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0033184 +name: positive regulation of histone ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein." [GOC:mah] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0031398 ! positive regulation of protein ubiquitination +is_a: GO:0033182 ! regulation of histone ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016574 ! histone ubiquitination +relationship: positively_regulates GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0033185 +name: dolichol-phosphate-mannose synthase complex +namespace: cellular_component +def: "A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively." [PMID:10835346] +synonym: "dolichyl-phosphate beta-D-mannosyltransferase complex" EXACT [] +synonym: "DPM synthase complex" EXACT [] +is_a: GO:0031501 ! mannosyltransferase complex + +[Term] +id: GO:0033186 +name: CAF-1 complex +namespace: cellular_component +def: "A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48." [PMID:17065558, PMID:17083276] +comment: In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90. +synonym: "chromatin assembly factor 1 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0033187 +name: obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate." [PMID:17412958, PMID:17412959] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "inositol hexakisphosphate 4-kinase or 6-kinase activity" EXACT [] +is_obsolete: true +consider: GO:0000830 +consider: GO:0000831 + +[Term] +id: GO:0033188 +name: sphingomyelin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin." [EC:2.7.8.27, RHEA:18765] +synonym: "ceramide:phosphatidylcholine cholinephosphotransferase activity" EXACT [EC:2.7.8.27] +synonym: "phosphatidylcholine:ceramide cholinephosphotransferase activity" EXACT [EC:2.7.8.27] +synonym: "SM synthase activity" EXACT [EC:2.7.8.27] +synonym: "SMS1" RELATED [EC:2.7.8.27] +synonym: "SMS2" RELATED [EC:2.7.8.27] +xref: EC:2.7.8.27 +xref: KEGG_REACTION:R08969 +xref: MetaCyc:2.7.8.27-RXN +xref: Reactome:R-HSA-429786 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]" +xref: Reactome:R-HSA-429798 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]" +xref: RHEA:18765 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0033189 +name: response to vitamin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus." [GOC:sl] +synonym: "response to retinol" NARROW [] +is_a: GO:0033273 ! response to vitamin +is_a: GO:0033993 ! response to lipid + +[Term] +id: GO:0033190 +name: solanapyrone synthase activity +namespace: molecular_function +def: "Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A." [GOC:cb, PMID:9659400] +is_a: GO:0009975 ! cyclase activity + +[Term] +id: GO:0033191 +name: macrophomate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate." [GOC:cb, PMID:10984474] +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0033192 +name: calmodulin-dependent protein phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin." [GOC:mah, PMID:15359118] +synonym: "Ca2+/CaM-dependent protein phosphatase activity" RELATED [] +synonym: "calcineurin activity" NARROW [] +synonym: "calcium- and calmodulin-dependent protein phosphatase activity" EXACT [] +synonym: "calcium/calmodulin-dependent protein phosphatase activity" EXACT [] +xref: Reactome:R-HSA-2730849 "Calcineurin binds and dephosphorylates NFAT" +xref: Reactome:R-HSA-4551451 "Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling" +is_a: GO:0004723 ! calcium-dependent protein serine/threonine phosphatase activity + +[Term] +id: GO:0033193 +name: Lsd1/2 complex +namespace: cellular_component +def: "A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast." [GOC:vw, PMID:17371846, PMID:17434129, PMID:17440621] +synonym: "SAPHIRE complex" EXACT [PMID:17371846] +synonym: "Swm complex" EXACT [PMID:17440621] +synonym: "Swm1/2 complex" RELATED [PMID:17440621] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0033194 +name: response to hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH." [GOC:mah] +is_a: GO:0006979 ! response to oxidative stress +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0033195 +name: response to alkyl hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group." [GOC:mah] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0033194 ! response to hydroperoxide + +[Term] +id: GO:0033196 +name: tryparedoxin peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O." [GOC:mah] +synonym: "TXNPx activity" EXACT [] +xref: MetaCyc:1.11.1.15-RXN +is_a: GO:0004601 ! peroxidase activity +is_a: GO:0051920 ! peroxiredoxin activity + +[Term] +id: GO:0033197 +name: response to vitamin E +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus." [GOC:sl] +synonym: "response to DL-alpha-tocopherol acetate" NARROW [] +synonym: "response to DL-alpha-tocopheryl acetate" NARROW [] +synonym: "response to O-Acetyl-alpha-tocopherol" NARROW [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0033198 +name: response to ATP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus." [GOC:sl] +synonym: "response to adenosine 5'-triphosphate" EXACT [] +synonym: "response to adenosine triphosphate" EXACT [] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0042493 ! response to drug +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0033199 +name: obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [PMID:17412958] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "inositol heptakisphosphate 4-kinase or 6-kinase activity" EXACT [] +is_obsolete: true +consider: GO:0000833 +consider: GO:0000834 + +[Term] +id: GO:0033200 +name: inositol heptakisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [PMID:17412958] +synonym: "diphosphoinositol-pentakisphosphate 5-kinase activity" EXACT [] +synonym: "IP7 5-kinase activity" EXACT [] +is_a: GO:0000829 ! inositol heptakisphosphate kinase activity + +[Term] +id: GO:0033201 +name: alpha-1,4-glucan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP." [PMID:17472966] +synonym: "1,4-alpha-glucan synthase activity" EXACT [] +xref: EC:2.4.1.21 +xref: RHEA:18189 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0033202 +name: DNA helicase complex +namespace: cellular_component +def: "A protein complex that possesses DNA helicase activity." [GOC:mah] +subset: goslim_metagenomics +subset: goslim_pir +is_a: GO:1904949 ! ATPase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0033203 +name: DNA helicase A complex +namespace: cellular_component +def: "A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction." [PMID:9341218] +is_a: GO:0033202 ! DNA helicase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033204 +name: ribonuclease P RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the RNA subunit of ribonuclease P." [GOC:pg, PMID:11455963] +synonym: "RNase P RNA binding" EXACT [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0033206 +name: meiotic cytokinesis +namespace: biological_process +def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells." [GOC:mtg_cell_cycle] +synonym: "cytokinesis after meiosis" EXACT [] +is_a: GO:0061640 ! cytoskeleton-dependent cytokinesis +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0061640 ! cytoskeleton-dependent cytokinesis +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0033207 +name: beta-1,4-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage." [GOC:mah] +synonym: "beta-1,4-GalNAc transferase activity" EXACT [] +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0033208 +name: UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide." [GOC:mah, PMID:12678917, PMID:16024623] +synonym: "Sda beta 1,4GalNAc transferase" RELATED [] +synonym: "UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] +is_a: GO:0033207 ! beta-1,4-N-acetylgalactosaminyltransferase activity + +[Term] +id: GO:0033209 +name: tumor necrosis factor-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] +synonym: "adipocytokine signaling pathway" RELATED [] +synonym: "TNF-alpha-mediated signaling pathway" NARROW [] +synonym: "tumor necrosis factor alpha-mediated signaling pathway" NARROW [] +synonym: "tumor necrosis factor-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071356 ! cellular response to tumor necrosis factor + +[Term] +id: GO:0033210 +name: leptin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body." [GOC:mah, GOC:signaling, GOC:yaf] +synonym: "adipocytokine signaling pathway" RELATED [] +synonym: "leptin-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0044320 ! cellular response to leptin stimulus + +[Term] +id: GO:0033211 +name: adiponectin-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:20536390] +synonym: "adipocytokine signaling pathway" RELATED [] +synonym: "adiponectin-mediated signaling pathway" RELATED [] +synonym: "adiponectin-mediated signalling pathway" EXACT [] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0033212 +name: iron import into cell +namespace: biological_process +alt_id: GO:0070627 +def: "The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis." [PMID:18622392, PMID:23192658, Wikipedia:Human_iron_metabolism] +synonym: "ferrous ion import" NARROW [] +synonym: "ferrous iron import" NARROW [] +synonym: "ferrous iron uptake" NARROW [] +synonym: "iron assimilation" RELATED [] +is_a: GO:0006826 ! iron ion transport +is_a: GO:0006879 ! cellular iron ion homeostasis +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0098657 ! import into cell +created_by: mah +creation_date: 2009-05-01T04:19:14Z + +[Term] +id: GO:0033214 +name: siderophore-dependent iron import into cell +namespace: biological_process +alt_id: GO:0015688 +alt_id: GO:0033213 +def: "A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors." [GOC:mah, PMID:16963626] +synonym: "iron assimilation by capture and transport" RELATED [] +synonym: "iron assimilation by chelation and transport" EXACT [] +synonym: "iron chelate transport" BROAD [] +is_a: GO:0033212 ! iron import into cell +is_a: GO:1901678 ! iron coordination entity transport +relationship: has_part GO:0098711 ! iron ion import across plasma membrane + +[Term] +id: GO:0033215 +name: reductive iron assimilation +namespace: biological_process +def: "A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins." [GOC:cjm, GOC:mah, PMID:16963626] +synonym: "iron assimilation by reduction and transport" EXACT [] +is_a: GO:0033212 ! iron import into cell +relationship: has_part GO:0000293 ! ferric-chelate reductase activity +relationship: has_part GO:0034755 ! iron ion transmembrane transport + +[Term] +id: GO:0033217 +name: regulation of transcription from RNA polymerase II promoter in response to iron ion starvation +namespace: biological_process +def: "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions." [GOC:mah] +synonym: "regulation of transcription from RNA polymerase II promoter in response to iron deficiency" EXACT [] +is_a: GO:0010106 ! cellular response to iron ion starvation +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress + +[Term] +id: GO:0033218 +name: amide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:mah] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0033219 +name: urea binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2." [GOC:mah, ISBN:0198506732] +is_a: GO:0033218 ! amide binding +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0033220 +name: ATPase-coupled amide-transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in)." [GOC:mah] +synonym: "amide-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent amide-transporter activity" EXACT [] +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity + +[Term] +id: GO:0033221 +name: ATPase-coupled urea transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in)." [GOC:mlg] +synonym: "ATP-dependent urea transmembrane transporter activity" EXACT [] +synonym: "carbamide-transporting ATPase activity" EXACT [] +synonym: "urea-transporting ATPase activity" EXACT [] +xref: RHEA:32803 +is_a: GO:0015204 ! urea transmembrane transporter activity +is_a: GO:0033220 ! ATPase-coupled amide-transporter activity + +[Term] +id: GO:0033222 +name: xylose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the D- or L-enantiomer of xylose." [GOC:mah] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0033223 +name: 2-aminoethylphosphonate transport +namespace: biological_process +def: "The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mlg] +synonym: "2-phosphonoethylamine transport" EXACT [] +synonym: "ciliatine transport" EXACT [] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0033224 +name: 2-aminoethylphosphonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other." [GOC:mlg] +synonym: "2-phosphonoethylamine transmembrane transporter activity" EXACT [] +synonym: "ciliatine transporter activity" EXACT [] +is_a: GO:0022804 ! active transmembrane transporter activity +relationship: part_of GO:0033223 ! 2-aminoethylphosphonate transport + +[Term] +id: GO:0033225 +name: ATPase-coupled 2-aminoethylphosphonate transporter activity +namespace: molecular_function +def: "Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in)." [GOC:mlg] +synonym: "2-aminoethylphosphonate transporting ATPase activity" RELATED [] +synonym: "2-aminoethylphosphonate-transporting ATPase activity" EXACT [] +synonym: "2-phosphonoethylamine transporting ATPase activity" EXACT [] +synonym: "ATP-dependent 2-aminoethylphosphonate transporter activity" EXACT [] +synonym: "ciliatine transportingATPase activity" EXACT [] +xref: RHEA:32775 +is_a: GO:0033224 ! 2-aminoethylphosphonate transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0033226 +name: 2-aminoethylphosphonate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 2-aminoethylphosphonate." [GOC:mlg] +synonym: "2-phosphonoethylamine binding" EXACT [] +synonym: "ciliatine binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0033227 +name: dsRNA transport +namespace: biological_process +def: "The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0050658 ! RNA transport + +[Term] +id: GO:0033228 +name: cysteine export across plasma membrane +namespace: biological_process +def: "The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:mlg] +synonym: "cysteine export" BROAD [] +is_a: GO:0032973 ! amino acid export across plasma membrane +is_a: GO:1903712 ! cysteine transmembrane transport + +[Term] +id: GO:0033229 +name: cysteine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cysteine from one side of a membrane to the other." [GOC:mah] +is_a: GO:0000099 ! sulfur amino acid transmembrane transporter activity +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +relationship: part_of GO:1903712 ! cysteine transmembrane transport + +[Term] +id: GO:0033230 +name: ATPase-coupled cysteine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0032519 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out)." [GOC:mlg] +synonym: "ATP-dependent cysteine transporter activity" EXACT [] +synonym: "ATPase-coupled cysteine transporter activity" RELATED [] +synonym: "cysteine exporter" RELATED [] +synonym: "cysteine-exporting ATPase activity" RELATED [] +synonym: "cysteine-transporting ATPase activity" EXACT [] +xref: RHEA:32795 +is_a: GO:0015424 ! ATPase-coupled amino acid transmembrane transporter activity +is_a: GO:0033229 ! cysteine transmembrane transporter activity + +[Term] +id: GO:0033231 +name: carbohydrate export +namespace: biological_process +def: "The directed movement of carbohydrates out of a cell or organelle." [GOC:mlg] +is_a: GO:0008643 ! carbohydrate transport + +[Term] +id: GO:0033232 +name: ATPase-coupled D-methionine transporter activity +namespace: molecular_function +alt_id: GO:0032521 +alt_id: GO:0032522 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out)." [GOC:mlg, PMID:18621668] +synonym: "ATP-dependent D-methionine transporter activity" EXACT [] +synonym: "D-methionine exporter" RELATED [] +synonym: "D-methionine importer" RELATED [] +synonym: "D-methionine-exporting ATPase activity" RELATED [] +synonym: "D-methionine-importing ATPase activity" RELATED [] +synonym: "D-methionine-transporting ATPase activity" EXACT [] +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0033233 +name: regulation of protein sumoylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein." [GOC:mah] +synonym: "regulation of sumoylation" EXACT [] +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016925 ! protein sumoylation +relationship: regulates GO:0016925 ! protein sumoylation + +[Term] +id: GO:0033234 +name: negative regulation of protein sumoylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein." [GOC:mah] +synonym: "negative regulation of sumoylation" EXACT [] +is_a: GO:0033233 ! regulation of protein sumoylation +is_a: GO:1903321 ! negative regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016925 ! protein sumoylation +relationship: negatively_regulates GO:0016925 ! protein sumoylation + +[Term] +id: GO:0033235 +name: positive regulation of protein sumoylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein." [GOC:mah] +synonym: "positive regulation of sumoylation" EXACT [] +is_a: GO:0033233 ! regulation of protein sumoylation +is_a: GO:1903322 ! positive regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016925 ! protein sumoylation +relationship: positively_regulates GO:0016925 ! protein sumoylation + +[Term] +id: GO:0033236 +name: obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+." [PMID:15761036] +synonym: "11-beta-hydroxysteroid dehydrogenase (NAD+) activity" EXACT [] +is_obsolete: true +replaced_by: GO:0070523 + +[Term] +id: GO:0033237 +name: obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+." [EC:1.1.1.146] +synonym: "11-beta-hydroxysteroid dehydrogenase (NADP+) activity" EXACT [] +synonym: "11beta-hydroxysteroid:NADP+ 11-oxidoreductase" EXACT [EC:1.1.1.146] +synonym: "beta-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.146] +synonym: "corticosteroid 11-beta-dehydrogenase activity" EXACT [EC:1.1.1.146] +xref: EC:1.1.1.146 +xref: MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN +is_obsolete: true +replaced_by: GO:0070524 + +[Term] +id: GO:0033238 +name: regulation of cellular amine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] +synonym: "regulation of amine metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044106 ! cellular amine metabolic process +relationship: regulates GO:0044106 ! cellular amine metabolic process + +[Term] +id: GO:0033239 +name: negative regulation of cellular amine metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] +synonym: "negative regulation of amine metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044106 ! cellular amine metabolic process +relationship: negatively_regulates GO:0044106 ! cellular amine metabolic process + +[Term] +id: GO:0033240 +name: positive regulation of cellular amine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] +synonym: "positive regulation of amine metabolism" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044106 ! cellular amine metabolic process +relationship: positively_regulates GO:0044106 ! cellular amine metabolic process + +[Term] +id: GO:0033241 +name: regulation of cellular amine catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] +synonym: "regulation of amine breakdown" EXACT [] +synonym: "regulation of amine catabolism" EXACT [] +synonym: "regulation of amine degradation" EXACT [] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009310 ! amine catabolic process +relationship: regulates GO:0009310 ! amine catabolic process + +[Term] +id: GO:0033242 +name: negative regulation of cellular amine catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] +synonym: "negative regulation of amine breakdown" EXACT [] +synonym: "negative regulation of amine catabolism" EXACT [] +synonym: "negative regulation of amine degradation" EXACT [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:0033241 ! regulation of cellular amine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009310 ! amine catabolic process +relationship: negatively_regulates GO:0009310 ! amine catabolic process + +[Term] +id: GO:0033243 +name: positive regulation of cellular amine catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] +synonym: "positive regulation of amine breakdown" EXACT [] +synonym: "positive regulation of amine catabolism" EXACT [] +synonym: "positive regulation of amine degradation" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:0033241 ! regulation of cellular amine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009310 ! amine catabolic process +relationship: positively_regulates GO:0009310 ! amine catabolic process + +[Term] +id: GO:0033244 +name: regulation of penicillin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "regulation of penicillin metabolism" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042316 ! penicillin metabolic process +relationship: regulates GO:0042316 ! penicillin metabolic process + +[Term] +id: GO:0033245 +name: negative regulation of penicillin metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "negative regulation of penicillin metabolism" EXACT [] +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:0033244 ! regulation of penicillin metabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042316 ! penicillin metabolic process +relationship: negatively_regulates GO:0042316 ! penicillin metabolic process + +[Term] +id: GO:0033246 +name: positive regulation of penicillin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "positive regulation of penicillin metabolism" EXACT [] +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:0033244 ! regulation of penicillin metabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042316 ! penicillin metabolic process +relationship: positively_regulates GO:0042316 ! penicillin metabolic process + +[Term] +id: GO:0033247 +name: regulation of penicillin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "regulation of penicillin breakdown" EXACT [] +synonym: "regulation of penicillin catabolism" EXACT [] +synonym: "regulation of penicillin degradation" EXACT [] +is_a: GO:0033244 ! regulation of penicillin metabolic process +is_a: GO:0034251 ! regulation of cellular amide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042317 ! penicillin catabolic process +relationship: regulates GO:0042317 ! penicillin catabolic process + +[Term] +id: GO:0033248 +name: negative regulation of penicillin catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "negative regulation of penicillin breakdown" EXACT [] +synonym: "negative regulation of penicillin catabolism" EXACT [] +synonym: "negative regulation of penicillin degradation" EXACT [] +is_a: GO:0033245 ! negative regulation of penicillin metabolic process +is_a: GO:0033247 ! regulation of penicillin catabolic process +is_a: GO:0034252 ! negative regulation of cellular amide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042317 ! penicillin catabolic process +relationship: negatively_regulates GO:0042317 ! penicillin catabolic process + +[Term] +id: GO:0033249 +name: positive regulation of penicillin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] +synonym: "positive regulation of penicillin breakdown" EXACT [] +synonym: "positive regulation of penicillin catabolism" EXACT [] +synonym: "positive regulation of penicillin degradation" EXACT [] +is_a: GO:0033246 ! positive regulation of penicillin metabolic process +is_a: GO:0033247 ! regulation of penicillin catabolic process +is_a: GO:0034253 ! positive regulation of cellular amide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042317 ! penicillin catabolic process +relationship: positively_regulates GO:0042317 ! penicillin catabolic process + +[Term] +id: GO:0033250 +name: penicillinase activity +namespace: molecular_function +def: "Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin." [GOC:mlg] +xref: MetaCyc:BETA-LACTAMASE-RXN +is_a: GO:0008800 ! beta-lactamase activity + +[Term] +id: GO:0033251 +name: cephalosporinase activity +namespace: molecular_function +def: "Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin." [GOC:mlg] +xref: MetaCyc:BETA-LACTAMASE-RXN +is_a: GO:0008800 ! beta-lactamase activity + +[Term] +id: GO:0033252 +name: regulation of beta-lactamase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid." [GOC:mah] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008800 ! beta-lactamase activity +relationship: regulates GO:0008800 ! beta-lactamase activity + +[Term] +id: GO:0033253 +name: regulation of penicillinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative." [GOC:mah] +is_a: GO:0033252 ! regulation of beta-lactamase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033250 ! penicillinase activity +relationship: regulates GO:0033250 ! penicillinase activity + +[Term] +id: GO:0033254 +name: vacuolar transporter chaperone complex +namespace: cellular_component +def: "A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p." [PMID:11823419, PMID:17079729] +synonym: "VTC complex" EXACT [] +is_a: GO:0101031 ! chaperone complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0033255 +name: SAS acetyltransferase complex +namespace: cellular_component +def: "A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p." [PMID:11731480, PMID:12626510, PMID:15788653] +synonym: "SAS-I complex" EXACT [] +is_a: GO:0032777 ! Piccolo NuA4 histone acetyltransferase complex + +[Term] +id: GO:0033256 +name: I-kappaB/NF-kappaB complex +namespace: cellular_component +def: "A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm." [GOC:bf, GOC:mah, PMID:9407099] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0033257 +name: Bcl3/NF-kappaB2 complex +namespace: cellular_component +def: "A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription." [GOC:mah, PMID:9407099] +synonym: "Bcl3-NFKB2 complex" RELATED [] +synonym: "Bcl3-p52 complex" EXACT [] +is_a: GO:0033256 ! I-kappaB/NF-kappaB complex + +[Term] +id: GO:0033258 +name: plastid DNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving plastid DNA." [GOC:mah] +synonym: "plastid DNA metabolism" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0009657 ! plastid organization + +[Term] +id: GO:0033259 +name: plastid DNA replication +namespace: biological_process +def: "The process in which new strands of DNA are synthesized in a plastid." [GOC:mah] +synonym: "plastid DNA synthesis" RELATED [] +synonym: "replication of plastid DNA" EXACT [] +is_a: GO:0006261 ! DNA-dependent DNA replication +is_a: GO:0033258 ! plastid DNA metabolic process +intersection_of: GO:0006261 ! DNA-dependent DNA replication +intersection_of: occurs_in GO:0009536 ! plastid +relationship: occurs_in GO:0009536 ! plastid +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0033260 +name: nuclear DNA replication +namespace: biological_process +def: "The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." [GOC:mtg_cell_cycle] +synonym: "DNA replication during S phase" RELATED [GOC:dph, GOC:tb] +synonym: "DNA replication involved in S phase" EXACT [] +synonym: "DNA replication involved in S-phase" EXACT [] +synonym: "nuclear cell cycle DNA replication" EXACT [] +is_a: GO:0044786 ! cell cycle DNA replication +intersection_of: GO:0006260 ! DNA replication +intersection_of: occurs_in GO:0005634 ! nucleus +intersection_of: part_of GO:0007049 ! cell cycle +relationship: occurs_in GO:0005634 ! nucleus + +[Term] +id: GO:0033261 +name: obsolete regulation of S phase +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle." [GOC:dph, GOC:mah, GOC:tb] +comment: This term was made obsolete because cell cycle phases are intervals and so cannot be regulated as such, rather it is the transitions between the phases that are regulated. This term was often also used to annotate genes which should have been annotated to 'regulation of DNA replication', or one of its children. +synonym: "regulation of progression through S phase" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of S phase" EXACT [] +synonym: "regulation of S-phase" EXACT [] +xref: MetaCyc:PWY-5043 +xref: MetaCyc:SALVADEHYPOX-PWY +xref: MetaCyc:SALVPURINE2-PWY +is_obsolete: true +consider: GO:0044770 + +[Term] +id: GO:0033262 +name: regulation of nuclear cell cycle DNA replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." [GOC:mtg_cell_cycle] +synonym: "regulation of DNA replication during S phase" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of DNA replication involved in S phase" EXACT [] +synonym: "regulation of DNA replication involved in S-phase" EXACT [] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033260 ! nuclear DNA replication +relationship: regulates GO:0033260 ! nuclear DNA replication + +[Term] +id: GO:0033263 +name: CORVET complex +namespace: cellular_component +def: "A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p." [PMID:17488625] +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005768 ! endosome + +[Term] +id: GO:0033264 +name: obsolete bontoxilysin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates." [EC:3.4.24.69] +comment: This term was made obsolete because it represents a gene product. +synonym: "BoNT" RELATED [EC:3.4.24.69] +synonym: "bontoxilysin activity" EXACT [] +synonym: "botulinum neurotoxin activity" EXACT [] +xref: EC:3.4.24.69 +xref: MetaCyc:3.4.24.69-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0033265 +name: choline binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium." [GOC:mlg] +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0033266 +name: ATPase-coupled choline transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane." [GOC:mlg] +synonym: "ATP-dependent choline transmembrane transporter activity" EXACT [] +synonym: "choline-transporting ATPase activity" EXACT [] +is_a: GO:0015220 ! choline transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0033267 +name: obsolete axon part +namespace: cellular_component +def: "OBSOLETE. A part of an axon, a cell projection of a neuron." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +xref: NIF_Subcellular:sao280355188 +is_obsolete: true +consider: GO:0030424 + +[Term] +id: GO:0033268 +name: node of Ranvier +namespace: cellular_component +def: "An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed." [GOC:mh] +synonym: "node of Ranvier axon" RELATED [NIF_Subcellular:sao188049490] +xref: NIF_Subcellular:birnlex_1152_2 +xref: Wikipedia:Nodes_of_Ranvier +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0033269 +name: internode region of axon +namespace: cellular_component +def: "An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath." [GOC:mah, GOC:mh] +synonym: "internode" EXACT [] +xref: NIF_Subcellular:sao206157942 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0033270 +name: paranode region of axon +namespace: cellular_component +def: "An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath." [GOC:mah, GOC:mh, NIF_Subcellular:sao936144858] +synonym: "paranode" EXACT [] +xref: NIF_Subcellular:sao234066064 +xref: NIF_Subcellular:sao936144858 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0033271 +name: myo-inositol phosphate transport +namespace: biological_process +def: "The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0033272 +name: myo-inositol hexakisphosphate transport +namespace: biological_process +def: "The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "phytate transport" EXACT [] +is_a: GO:0015893 ! drug transport +is_a: GO:0033271 ! myo-inositol phosphate transport + +[Term] +id: GO:0033273 +name: response to vitamin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus." [GOC:sl] +is_a: GO:0007584 ! response to nutrient + +[Term] +id: GO:0033274 +name: response to vitamin B2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus." [GOC:sl] +synonym: "response to riboflavin" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0033275 +name: actin-myosin filament sliding +namespace: biological_process +def: "The sliding movement of actin thin filaments and myosin thick filaments past each other." [GOC:pf] +synonym: "actin filament sliding" RELATED [] +is_a: GO:0070252 ! actin-mediated cell contraction + +[Term] +id: GO:0033276 +name: transcription factor TFTC complex +namespace: cellular_component +def: "A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity." [PMID:10373431, PMID:9603525] +is_a: GO:0070461 ! SAGA-type complex +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0016591 ! RNA polymerase II, holoenzyme + +[Term] +id: GO:0033277 +name: abortive mitotic cell cycle +namespace: biological_process +def: "A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy." [GOC:mah, PMID:9573008] +comment: Note that this term should be used only for abortive mitotic events that occur normally, e.g. during megakaryocyte differentiation; it should not be used for incomplete mitosis resulting from mutation or other abnormal occurrences. Note that this term should not be confused with 'endomitotic cell cycle ; GO:0007113', which describes a process in which no mitotic spindle forms. +synonym: "abortive mitosis" RELATED [] +is_a: GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0033278 +name: cell proliferation in midbrain +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf] +synonym: "cell proliferation in mesencephalon" EXACT [] +synonym: "mesencepahalic cell proliferation" RELATED [] +is_a: GO:0061351 ! neural precursor cell proliferation +relationship: part_of GO:0030901 ! midbrain development + +[Term] +id: GO:0033280 +name: response to vitamin D +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus." [GOC:sl] +synonym: "response to calciferol" EXACT [] +synonym: "response to cholecalciferol" NARROW [] +synonym: "response to ergocalciferol" NARROW [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0033281 +name: TAT protein transport complex +namespace: cellular_component +def: "A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins." [GOC:pamgo_curators] +synonym: "TAT protein secretion complex" NARROW [] +synonym: "TAT protein translocation system complex" NARROW [] +synonym: "Twin-arginine translocation complex" NARROW [] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0033282 +name: protein C inhibitor-acrosin complex +namespace: cellular_component +def: "A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin." [GOC:pr, PMID:11120760, PMID:7521127] +synonym: "PCI-ACR complex" EXACT [PR:000003652, PR:000014685] +synonym: "PCI-acrosin complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-acrosin complex" EXACT [PR:000014685] +synonym: "serpin A5-acrosin complex" EXACT [PR:000014685] +synonym: "SERPINA5-acrosin complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0002080 ! acrosomal membrane + +[Term] +id: GO:0033283 +name: ATPase-coupled organic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out)." [GOC:mlg] +synonym: "ATP-dependent organic acid transmembrane transporter activity" EXACT [] +synonym: "organic acid-transporting ATPase activity" EXACT [] +is_a: GO:0005342 ! organic acid transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0033284 +name: ATPase-coupled carboxylic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out)." [GOC:mlg] +synonym: "ATP-dependent carboxylic acid transporter activity" EXACT [] +synonym: "carboxylic acid-transporting ATPase activity" EXACT [] +is_a: GO:0033283 ! ATPase-coupled organic acid transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity + +[Term] +id: GO:0033285 +name: ATPase-coupled monocarboxylic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out)." [GOC:mlg] +synonym: "ATP-dependent monocarboxylic acid transmembrane transporter activity" EXACT [] +synonym: "monocarboxylic acid-transporting ATPase activity" EXACT [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0033284 ! ATPase-coupled carboxylic acid transmembrane transporter activity + +[Term] +id: GO:0033286 +name: ATPase-coupled ectoine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0051471 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out)." [GOC:mlg] +synonym: "ATP-dependent ectoine transmembrane transporter activity" EXACT [] +synonym: "ectoine transmembrane transporter activity" BROAD [] +synonym: "ectoine-transporting ATPase activity" EXACT [] +xref: RHEA:32787 +xref: RHEA:32791 +is_a: GO:0033285 ! ATPase-coupled monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0051470 ! ectoine transport + +[Term] +id: GO:0033288 +name: ATPase-coupled hydroxyectoine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0033287 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out)." [GOC:mlg] +synonym: "ATP-dependent hydroxyectoine transmembrane transporter activity" EXACT [] +synonym: "hydroxyectoine transmembrane transporter activity" BROAD [] +synonym: "hydroxyectoine-transporting ATPase activity" EXACT [] +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0033285 ! ATPase-coupled monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0033308 ! hydroxyectoine transport + +[Term] +id: GO:0033289 +name: intraconoid microtubule +namespace: cellular_component +def: "A microtubule located such that it threads through the conoid and projects through the polar ring." [GOC:mah, PMID:11901169, PMID:16518471] +is_a: GO:0005874 ! microtubule +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0033290 +name: eukaryotic 48S preinitiation complex +namespace: cellular_component +alt_id: GO:0016283 +def: "A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA." [GOC:hjd, PMID:15145049] +synonym: "eukaryotic 48S initiation complex" RELATED [] +synonym: "eukaryotic 48S pre-initiation complex" EXACT [] +is_a: GO:0070993 ! translation preinitiation complex +relationship: has_part GO:0022627 ! cytosolic small ribosomal subunit + +[Term] +id: GO:0033291 +name: eukaryotic 80S initiation complex +namespace: cellular_component +def: "A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region." [GOC:hjd, PMID:15145049] +is_a: GO:0070992 ! translation initiation complex + +[Term] +id: GO:0033292 +name: T-tubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril." [GOC:dph, GOC:jl, GOC:mah] +synonym: "T-tubule organisation" EXACT [GOC:mah] +synonym: "T-tubule organization and biogenesis" RELATED [GOC:mah] +synonym: "transverse tubule organization" EXACT [GOC:rl] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0007009 ! plasma membrane organization +relationship: part_of GO:0055001 ! muscle cell development + +[Term] +id: GO:0033293 +name: monocarboxylic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:mah] +is_a: GO:0031406 ! carboxylic acid binding + +[Term] +id: GO:0033294 +name: ectoine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid." [GOC:mah] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0033295 +name: hydroxyectoine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hydroxyectoine." [GOC:mlg] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0043178 ! alcohol binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0033296 +name: rhamnose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose." [GOC:mah] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0033297 +name: ATPase-coupled rhamnose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out)." [GOC:mlg] +synonym: "ATP-dependent rhamnose transmembrane transporter activity" EXACT [] +synonym: "rhamnose-transporting ATPase activity" EXACT [] +is_a: GO:0015153 ! rhamnose transmembrane transporter activity +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity + +[Term] +id: GO:0033298 +name: contractile vacuole organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores." [GOC:mah] +synonym: "contractile vacuole organisation" EXACT [GOC:mah] +synonym: "contractile vacuole organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007033 ! vacuole organization +is_a: GO:0016050 ! vesicle organization + +[Term] +id: GO:0033299 +name: secretion of lysosomal enzymes +namespace: biological_process +def: "The controlled release of lysosomal enzymes by a cell." [GOC:mah] +is_a: GO:0009306 ! protein secretion + +[Term] +id: GO:0033300 +name: dehydroascorbic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other." [GOC:go_curators] +synonym: "dehydroascorbate transporter activity" EXACT [] +synonym: "dehydroascorbic acid transporter activity" RELATED [] +xref: Reactome:R-HSA-198818 "GLUT1/3 transports extracellular DHvitC to cytosol" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0070837 ! dehydroascorbic acid transport + +[Term] +id: GO:0033301 +name: cell cycle comprising mitosis without cytokinesis +namespace: biological_process +def: "A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N)." [GOC:expert_vm, GOC:mah] +comment: Note that this term should be used for naturally occurring instances of mitosis without cytokinesis, e.g. in the tapetum of flowers and in a number of lower eukaryotes; it should not be used for abnormal events such as may occur in cancers. +is_a: GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0033302 +name: quercetin O-glucoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving O-glucosylated derivatives of quercetin." [GOC:mah, MetaCyc:PWY-5321] +synonym: "quercetin O-glucoside metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0051552 ! flavone metabolic process + +[Term] +id: GO:0033303 +name: quercetin O-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin." [GOC:mah, MetaCyc:PWY-5321] +synonym: "quercetin O-glucoside anabolism" EXACT [] +synonym: "quercetin O-glucoside biosynthesis" EXACT [] +synonym: "quercetin O-glucoside formation" EXACT [] +synonym: "quercetin O-glucoside synthesit" EXACT [] +xref: MetaCyc:PWY-5321 +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0033302 ! quercetin O-glucoside metabolic process +is_a: GO:0051553 ! flavone biosynthetic process + +[Term] +id: GO:0033304 +name: chlorophyll a metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorophyll a." [GOC:mah] +synonym: "chlorophyll a metabolism" EXACT [] +is_a: GO:0015994 ! chlorophyll metabolic process + +[Term] +id: GO:0033305 +name: chlorophyll a biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of chlorophyll a." [GOC:mah] +synonym: "chlorophyll a anabolism" EXACT [] +synonym: "chlorophyll a biosynthesis" EXACT [] +synonym: "chlorophyll a formation" EXACT [] +synonym: "chlorophyll a synthesis" EXACT [] +is_a: GO:0015995 ! chlorophyll biosynthetic process +is_a: GO:0033304 ! chlorophyll a metabolic process + +[Term] +id: GO:0033306 +name: phytol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol." [GOC:mah] +synonym: "phytol metabolism" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:1903173 ! fatty alcohol metabolic process + +[Term] +id: GO:0033307 +name: phytol salvage +namespace: biological_process +def: "A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis." [GOC:mah, MetaCyc:PWY-5107] +synonym: "phytol salvage pathway" EXACT [] +xref: MetaCyc:PWY-5107 +is_a: GO:0033520 ! phytol biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0033308 +name: hydroxyectoine transport +namespace: biological_process +def: "The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mlg] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0033309 +name: SBF transcription complex +namespace: cellular_component +def: "A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p." [GOC:mah, PMID:11206552, PMID:15838511, PMID:18160399, PMID:19150335, PMID:7917338] +synonym: "SBF complex" EXACT [GOC:mah] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0033310 +name: chlorophyll a catabolic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the breakdown of chlorophyll a." [GOC:mah] +synonym: "chlorophyll a breakdown" EXACT [] +synonym: "chlorophyll a catabolism" EXACT [] +synonym: "chlorophyll a degradation" EXACT [] +xref: MetaCyc:PWY-5086 +xref: MetaCyc:PWY-5098 +is_a: GO:0015996 ! chlorophyll catabolic process +is_a: GO:0033304 ! chlorophyll a metabolic process + +[Term] +id: GO:0033311 +name: chlorophyll a biosynthetic process via phytyl diphosphate +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate." [GOC:mah, MetaCyc:PWY-5086] +synonym: "chlorophyll a anabolism via phytyl diphosphate" EXACT [] +synonym: "chlorophyll a biosynthesis via phytyl diphosphate" EXACT [] +synonym: "chlorophyll a biosynthetic process via phytyl-PP" EXACT [] +synonym: "chlorophyll a formation via phytyl chlorophyll a formation via phytyl-PP" EXACT [] +synonym: "chlorophyll a synthesis via phytyl diphosphate" EXACT [] +xref: MetaCyc:PWY-5086 +is_a: GO:0033305 ! chlorophyll a biosynthetic process + +[Term] +id: GO:0033312 +name: chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a." [GOC:mah, MetaCyc:PWY-5064] +synonym: "chlorophyll a anabolism via geranylgeranyl-chlorophyll a" EXACT [] +synonym: "chlorophyll a biosynthesis via geranylgeranyl-chlorophyll a" EXACT [] +synonym: "chlorophyll a formation via geranylgeranyl-chlorophyll a" EXACT [] +synonym: "chlorophyll a synthesis via geranylgeranyl-chlorophyll a" EXACT [] +xref: MetaCyc:PWY-5064 +is_a: GO:0033305 ! chlorophyll a biosynthetic process + +[Term] +id: GO:0033313 +name: meiotic cell cycle checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage." [GOC:mtg_cell_cycle] +is_a: GO:0000075 ! cell cycle checkpoint +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0000075 ! cell cycle checkpoint +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0033314 +name: mitotic DNA replication checkpoint +namespace: biological_process +alt_id: GO:0031574 +def: "A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle DNA replication checkpoint" EXACT [] +synonym: "S-M checkpoint" EXACT [] +synonym: "S-M DNA replication checkpoint" EXACT [] +synonym: "S-phase checkpoint" BROAD [] +is_a: GO:0000076 ! DNA replication checkpoint +is_a: GO:0044774 ! mitotic DNA integrity checkpoint +is_a: GO:0044818 ! mitotic G2/M transition checkpoint +intersection_of: GO:0000076 ! DNA replication checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0033315 +name: meiotic G2/MI DNA replication checkpoint +namespace: biological_process +def: "A DNA integrity checkpoint that acts to inhibit the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete." [GOC:mtg_cell_cycle] +synonym: "meiotic cell cycle DNA replication checkpoint" EXACT [] +is_a: GO:0000076 ! DNA replication checkpoint +is_a: GO:0044778 ! meiotic DNA integrity checkpoint +is_a: GO:1901994 ! negative regulation of meiotic cell cycle phase transition +intersection_of: GO:0000076 ! DNA replication checkpoint +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0110031 ! negative regulation of G2/MI transition of meiotic cell cycle + +[Term] +id: GO:0033316 +name: meiotic spindle assembly checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mah] +is_a: GO:0044779 ! meiotic spindle checkpoint +is_a: GO:0071173 ! spindle assembly checkpoint +intersection_of: GO:0071173 ! spindle assembly checkpoint +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0033319 +name: UDP-D-xylose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate." [GOC:mah] +synonym: "UDP-D-xylose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033320 +name: UDP-D-xylose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate." [GOC:mah, MetaCyc:PWY-4821] +synonym: "UDP-D-xylose anabolism" EXACT [] +synonym: "UDP-D-xylose biosynthesis" EXACT [] +synonym: "UDP-D-xylose formation" EXACT [] +synonym: "UDP-D-xylose synthesis" EXACT [] +xref: MetaCyc:PWY-4821 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033319 ! UDP-D-xylose metabolic process + +[Term] +id: GO:0033321 +name: homomethionine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation." [GOC:mah, MetaCyc:PWY-1186] +synonym: "homomethionine metabolism" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0033322 +name: homomethionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation." [GOC:mah, MetaCyc:PWY-1186] +synonym: "homomethionine anabolism" EXACT [] +synonym: "homomethionine biosynthesis" EXACT [] +synonym: "homomethionine formation" EXACT [] +synonym: "homomethionine synthesis" EXACT [] +xref: MetaCyc:PWY-1186 +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0033321 ! homomethionine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0033323 +name: choline biosynthetic process via CDP-choline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline." [GOC:mah, MetaCyc:PWY-3561] +synonym: "choline anabolism via CDP-choline" EXACT [] +synonym: "choline biosynthesis via CDP-choline" EXACT [] +synonym: "choline formation via CDP-choline" EXACT [] +synonym: "choline synthesis via CDP-choline" EXACT [] +xref: MetaCyc:PWY-3561 +xref: MetaCyc:PWY-4762 +is_a: GO:0042425 ! choline biosynthetic process + +[Term] +id: GO:0033324 +name: choline biosynthetic process via N-monomethylethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine." [GOC:mah, MetaCyc:PWY-3542] +synonym: "choline anabolism via N-monomethylethanolamine" EXACT [] +synonym: "choline biosynthesis via N-monomethylethanolamine" EXACT [] +synonym: "choline formation via N-monomethylethanolamine" EXACT [] +synonym: "choline synthesis via N-monomethylethanolamine" EXACT [] +xref: MetaCyc:PWY-3542 +xref: MetaCyc:PWY-4762 +is_a: GO:0042425 ! choline biosynthetic process + +[Term] +id: GO:0033325 +name: choline biosynthetic process via phosphoryl-ethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine." [GOC:mah, MetaCyc:PWY-3385] +synonym: "choline anabolism via phosphoryl-ethanolamine" EXACT [] +synonym: "choline biosynthesis via phosphoryl-ethanolamine" EXACT [] +synonym: "choline formation via phosphoryl-ethanolamine" EXACT [] +synonym: "choline synthesis via phosphoryl-ethanolamine" EXACT [] +xref: MetaCyc:PWY-3385 +xref: MetaCyc:PWY-4762 +is_a: GO:0042425 ! choline biosynthetic process + +[Term] +id: GO:0033326 +name: cerebrospinal fluid secretion +namespace: biological_process +def: "The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces." [GOC:ln, http://users.ahsc.arizona.edu/davis/csf.htm, PMID:10716451] +synonym: "CSF secretion" EXACT [] +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0032941 ! secretion by tissue + +[Term] +id: GO:0033327 +name: Leydig cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis." [GOC:ln, PMID:12050120] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0008584 ! male gonad development + +[Term] +id: GO:0033328 +name: peroxisome membrane targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane." [GOC:rb, PMID:15133130, PMID:17020786] +synonym: "mPTS binding" EXACT [] +synonym: "peroxisomal membrane protein (PMP) targeting signal (mPTS) binding" EXACT [PMID:14709540] +synonym: "PMP targeting signal (mPTS) binding" EXACT [PMID:14709540] +synonym: "PMP targeting signal binding" EXACT [PMID:14709540] +is_a: GO:0000268 ! peroxisome targeting sequence binding + +[Term] +id: GO:0033329 +name: kaempferol O-glucoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol." [GOC:mah, MetaCyc:PWY-5320] +synonym: "kaempferol O-glucoside metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0051552 ! flavone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process + +[Term] +id: GO:0033330 +name: kaempferol O-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol." [GOC:mah, MetaCyc:PWY-5320] +synonym: "kaempferol O-glucoside anabolism" EXACT [] +synonym: "kaempferol O-glucoside biosynthesis" EXACT [] +synonym: "kaempferol O-glucoside formation" EXACT [] +synonym: "kaempferol O-glucoside synthesit" EXACT [] +xref: MetaCyc:PWY-5320 +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0033329 ! kaempferol O-glucoside metabolic process +is_a: GO:0051553 ! flavone biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process + +[Term] +id: GO:0033331 +name: ent-kaurene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins." [GOC:mah, MetaCyc:PWY-5032, PMID:17064690] +synonym: "ent-kaurene metabolism" EXACT [] +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0033332 +name: ent-kaurene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins." [GOC:mah, MetaCyc:PWY-5032, PMID:17064690] +synonym: "ent-kaurene anabolism" EXACT [] +synonym: "ent-kaurene biosynthesis" EXACT [] +synonym: "ent-kaurene formation" EXACT [] +synonym: "ent-kaurene synthesis" EXACT [] +xref: MetaCyc:PWY-5032 +xref: MetaCyc:PWY-5035 +is_a: GO:0033331 ! ent-kaurene metabolic process +is_a: GO:0046246 ! terpene biosynthetic process + +[Term] +id: GO:0033333 +name: fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0048736 ! appendage development + +[Term] +id: GO:0033334 +name: fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a fin are generated and organized." [GOC:dgh] +is_a: GO:0035107 ! appendage morphogenesis +relationship: part_of GO:0033333 ! fin development + +[Term] +id: GO:0033335 +name: anal fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0033338 ! medial fin development + +[Term] +id: GO:0033336 +name: caudal fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0033338 ! medial fin development + +[Term] +id: GO:0033337 +name: dorsal fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0033338 ! medial fin development + +[Term] +id: GO:0033338 +name: medial fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure." [GOC:dgh] +synonym: "median fin development" EXACT [] +is_a: GO:0033333 ! fin development + +[Term] +id: GO:0033339 +name: pectoral fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0033333 ! fin development +is_a: GO:0060173 ! limb development + +[Term] +id: GO:0033340 +name: pelvic fin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0033333 ! fin development +is_a: GO:0060173 ! limb development + +[Term] +id: GO:0033341 +name: regulation of collagen binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collagen binding." [GOC:mah] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005518 ! collagen binding +relationship: regulates GO:0005518 ! collagen binding + +[Term] +id: GO:0033342 +name: negative regulation of collagen binding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding." [GOC:mah] +synonym: "down regulation of collagen binding" EXACT [] +synonym: "down-regulation of collagen binding" EXACT [] +synonym: "downregulation of collagen binding" EXACT [] +synonym: "inhibition of collagen binding" NARROW [] +is_a: GO:0033341 ! regulation of collagen binding +is_a: GO:0051100 ! negative regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005518 ! collagen binding +relationship: negatively_regulates GO:0005518 ! collagen binding + +[Term] +id: GO:0033343 +name: positive regulation of collagen binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collagen binding." [GOC:mah] +synonym: "activation of collagen binding" NARROW [] +synonym: "stimulation of collagen binding" NARROW [] +synonym: "up regulation of collagen binding" EXACT [] +synonym: "up-regulation of collagen binding" EXACT [] +synonym: "upregulation of collagen binding" EXACT [] +is_a: GO:0033341 ! regulation of collagen binding +is_a: GO:0051099 ! positive regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005518 ! collagen binding +relationship: positively_regulates GO:0005518 ! collagen binding + +[Term] +id: GO:0033344 +name: cholesterol efflux +namespace: biological_process +def: "The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle." [GOC:sart] +synonym: "cholesterol export" EXACT [] +is_a: GO:0030301 ! cholesterol transport + +[Term] +id: GO:0033345 +name: asparagine catabolic process via L-aspartate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate." [GOC:mah] +xref: MetaCyc:ASPARAGINE-DEG1-PWY +is_a: GO:0006530 ! asparagine catabolic process + +[Term] +id: GO:0033346 +name: asparagine catabolic process via 2-oxosuccinamate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate." [GOC:mah, MetaCyc:PWY-4002] +xref: MetaCyc:PWY-4002 +is_a: GO:0006530 ! asparagine catabolic process + +[Term] +id: GO:0033347 +name: tetrose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule." [GOC:mah] +synonym: "tetrose metabolism" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process + +[Term] +id: GO:0033348 +name: tetrose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule." [GOC:mah] +synonym: "tetrose anabolism" EXACT [] +synonym: "tetrose biosynthesis" EXACT [] +synonym: "tetrose formation" EXACT [] +synonym: "tetrose synthesis" EXACT [] +is_a: GO:0033347 ! tetrose metabolic process +is_a: GO:0046364 ! monosaccharide biosynthetic process + +[Term] +id: GO:0033349 +name: apiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose." [GOC:mah] +synonym: "apiose metabolism" EXACT [] +is_a: GO:0033347 ! tetrose metabolic process + +[Term] +id: GO:0033350 +name: apiose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose." [GOC:mah] +synonym: "apiose anabolism" EXACT [] +synonym: "apiose biosynthesis" EXACT [] +synonym: "apiose formation" EXACT [] +synonym: "apiose synthesis" EXACT [] +is_a: GO:0033348 ! tetrose biosynthetic process +is_a: GO:0033349 ! apiose metabolic process + +[Term] +id: GO:0033351 +name: UDP-D-apiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate." [GOC:mah] +synonym: "UDP-D-apiose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033352 +name: UDP-D-apiose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate." [GOC:mah, MetaCyc:PWY-5113] +synonym: "UDP-D-apiose anabolism" EXACT [] +synonym: "UDP-D-apiose biosynthesis" EXACT [] +synonym: "UDP-D-apiose formation" EXACT [] +synonym: "UDP-D-apiose synthesis" EXACT [] +xref: MetaCyc:PWY-4821 +xref: MetaCyc:PWY-5113 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033351 ! UDP-D-apiose metabolic process + +[Term] +id: GO:0033353 +name: S-adenosylmethionine cycle +namespace: biological_process +def: "A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine." [GOC:mah, MetaCyc:PWY-5041] +synonym: "activated methyl cycle" EXACT [] +synonym: "SAM cycle" EXACT [] +xref: MetaCyc:PWY-5041 +is_a: GO:0046500 ! S-adenosylmethionine metabolic process +relationship: has_part GO:0008898 ! S-adenosylmethionine-homocysteine S-methyltransferase activity + +[Term] +id: GO:0033354 +name: chlorophyll cycle +namespace: biological_process +def: "A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates." [GOC:mah, MetaCyc:PWY-5068] +xref: MetaCyc:PWY-5068 +is_a: GO:0015994 ! chlorophyll metabolic process + +[Term] +id: GO:0033355 +name: ascorbate glutathione cycle +namespace: biological_process +def: "A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH." [GOC:mah, MetaCyc:PWY-2261] +synonym: "hydrogen peroxide detoxification" RELATED [] +xref: MetaCyc:PWY-2261 +is_a: GO:0006749 ! glutathione metabolic process +is_a: GO:0019852 ! L-ascorbic acid metabolic process +is_a: GO:0042744 ! hydrogen peroxide catabolic process + +[Term] +id: GO:0033356 +name: UDP-L-arabinose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate." [GOC:mah] +synonym: "UDP-L-arabinose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033357 +name: L-arabinose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose." [GOC:mah] +synonym: "L-arabinose anabolism" EXACT [] +synonym: "L-arabinose biosynthesis" EXACT [] +synonym: "L-arabinose formation" EXACT [] +synonym: "L-arabinose synthesis" EXACT [] +is_a: GO:0019567 ! arabinose biosynthetic process +is_a: GO:0046373 ! L-arabinose metabolic process + +[Term] +id: GO:0033358 +name: UDP-L-arabinose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate." [GOC:mah, MetaCyc:PWY-82] +synonym: "UDP-L-arabinose anabolism" EXACT [] +synonym: "UDP-L-arabinose biosynthesis" EXACT [] +synonym: "UDP-L-arabinose formation" EXACT [] +synonym: "UDP-L-arabinose synthesis" EXACT [] +xref: MetaCyc:PWY-63 +xref: MetaCyc:PWY-82 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033356 ! UDP-L-arabinose metabolic process + +[Term] +id: GO:0033359 +name: lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:DAPLYSINESYN-PWY-] +synonym: "lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT [] +synonym: "lysine biosynthesis via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate" EXACT [] +synonym: "lysine biosynthetic process via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate" EXACT [] +synonym: "lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT [] +synonym: "lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate" EXACT [] +xref: MetaCyc:DAPLYSINESYN-PWY +is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate + +[Term] +id: GO:0033360 +name: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:PWY-2941] +synonym: "lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT [] +synonym: "lysine biosynthesis via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate" EXACT [] +synonym: "lysine biosynthetic process via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate" EXACT [] +synonym: "lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT [] +synonym: "lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate" EXACT [] +xref: MetaCyc:PWY-2941 +is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate + +[Term] +id: GO:0033361 +name: lysine biosynthetic process via diaminopimelate, dehydrogenase pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step." [GOC:mah, GOC:pr, MetaCyc:PWY-2942] +synonym: "lysine anabolism via diaminopimelate, dehydrogenase pathway" EXACT [] +synonym: "lysine biosynthesis via diaminopimelic acid, dehydrogenase pathway" EXACT [] +synonym: "lysine formation via diaminopimelate, dehydrogenase pathway" EXACT [] +synonym: "lysine synthesis via diaminopimelate, dehydrogenase pathway" EXACT [] +xref: MetaCyc:PWY-2942 +is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate +relationship: has_part GO:0047850 ! diaminopimelate dehydrogenase activity + +[Term] +id: GO:0033362 +name: lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps." [GOC:mah, GOC:pr, MetaCyc:PWY-5097] +synonym: "lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT [] +synonym: "lysine biosynthesis via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT [] +synonym: "lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT [] +synonym: "lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway" EXACT [] +xref: MetaCyc:PWY-5097 +is_a: GO:0009089 ! lysine biosynthetic process via diaminopimelate +relationship: has_part GO:0008837 ! diaminopimelate epimerase activity +relationship: has_part GO:0010285 ! L,L-diaminopimelate aminotransferase activity + +[Term] +id: GO:0033363 +name: secretory granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] +synonym: "secretory granule organisation" EXACT [GOC:mah] +synonym: "secretory granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016050 ! vesicle organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0033364 +name: mast cell secretory granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] +synonym: "mast cell secretory granule maturation" RELATED [] +synonym: "mast cell secretory granule organisation" EXACT [GOC:mah] +synonym: "mast cell secretory granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033363 ! secretory granule organization + +[Term] +id: GO:0033365 +name: protein localization to organelle +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah] +synonym: "protein localisation to organelle" EXACT [GOC:mah] +synonym: "protein localization in organelle" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization + +[Term] +id: GO:0033366 +name: protein localization to secretory granule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah] +synonym: "protein localisation in secretory granule" EXACT [GOC:mah] +synonym: "protein localization in secretory granule" EXACT [] +is_a: GO:0033365 ! protein localization to organelle + +[Term] +id: GO:0033367 +name: protein localization to mast cell secretory granule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell." [GOC:mah] +synonym: "protein localisation in mast cell secretory granule" EXACT [GOC:mah] +synonym: "protein localization in mast cell secretory granule" EXACT [] +is_a: GO:0033366 ! protein localization to secretory granule +relationship: part_of GO:0033364 ! mast cell secretory granule organization + +[Term] +id: GO:0033368 +name: protease localization to mast cell secretory granule +namespace: biological_process +def: "Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell." [GOC:mah] +synonym: "protease localisation in mast cell secretory granule" EXACT [GOC:mah] +synonym: "protease localization in mast cell secretory granule" EXACT [] +is_a: GO:0033367 ! protein localization to mast cell secretory granule + +[Term] +id: GO:0033369 +name: establishment of protein localization to mast cell secretory granule +namespace: biological_process +def: "The directed movement of a protein to a location within a secretory granule in a mast cell." [GOC:mah] +synonym: "establishment of protein localisation in mast cell secretory granule" EXACT [GOC:mah] +synonym: "establishment of protein localization in mast cell secretory granule" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +relationship: part_of GO:0033367 ! protein localization to mast cell secretory granule + +[Term] +id: GO:0033370 +name: maintenance of protein location in mast cell secretory granule +namespace: biological_process +def: "A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of protein localization in mast cell secretory granule" RELATED [GOC:dph, GOC:tb] +synonym: "mast cell protein retention" EXACT [] +is_a: GO:0032507 ! maintenance of protein location in cell +relationship: part_of GO:0033367 ! protein localization to mast cell secretory granule + +[Term] +id: GO:0033371 +name: T cell secretory granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] +synonym: "T cell secretory granule organisation" EXACT [GOC:mah] +synonym: "T cell secretory granule organization and biogenesis" RELATED [GOC:mah] +synonym: "T lymphocyte secretory granule organization" EXACT [] +synonym: "T-cell secretory granule organization" EXACT [] +synonym: "T-lymphocyte secretory granule maturation" RELATED [] +synonym: "T-lymphocyte secretory granule organization" EXACT [] +is_a: GO:0033363 ! secretory granule organization + +[Term] +id: GO:0033372 +name: establishment of protease localization to mast cell secretory granule +namespace: biological_process +def: "The directed movement of a protease to a location within a secretory granule in a mast cell." [GOC:mah] +synonym: "establishment of protease localisation in mast cell secretory granule" EXACT [GOC:mah] +synonym: "establishment of protease localization in mast cell secretory granule" EXACT [] +is_a: GO:0033369 ! establishment of protein localization to mast cell secretory granule +relationship: part_of GO:0033368 ! protease localization to mast cell secretory granule + +[Term] +id: GO:0033373 +name: maintenance of protease location in mast cell secretory granule +namespace: biological_process +def: "A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of protease localization in mast cell secretory granule" RELATED [GOC:dph, GOC:tb] +synonym: "mast cell protease retention" EXACT [] +is_a: GO:0033370 ! maintenance of protein location in mast cell secretory granule +relationship: part_of GO:0033368 ! protease localization to mast cell secretory granule + +[Term] +id: GO:0033374 +name: protein localization to T cell secretory granule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell." [GOC:mah] +synonym: "protein localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "protein localization in T cell secretory granule" EXACT [] +synonym: "protein localization in T lymphocyte secretory granule" EXACT [] +synonym: "protein localization in T-cell secretory granule" EXACT [] +synonym: "protein localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033366 ! protein localization to secretory granule +relationship: part_of GO:0033371 ! T cell secretory granule organization + +[Term] +id: GO:0033375 +name: protease localization to T cell secretory granule +namespace: biological_process +def: "Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell." [GOC:mah] +synonym: "protease localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "protease localization in T cell secretory granule" EXACT [] +synonym: "protease localization in T lymphocyte secretory granule" EXACT [] +synonym: "protease localization in T-cell secretory granule" EXACT [] +synonym: "protease localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033374 ! protein localization to T cell secretory granule + +[Term] +id: GO:0033376 +name: establishment of protein localization to T cell secretory granule +namespace: biological_process +def: "The directed movement of a protein to a location within a secretory granule in a T cell." [GOC:mah] +synonym: "establishment of protein localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "establishment of protein localization in T cell secretory granule" EXACT [] +synonym: "establishment of protein localization in T lymphocyte secretory granule" EXACT [] +synonym: "establishment of protein localization in T-cell secretory granule" EXACT [] +synonym: "establishment of protein localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +relationship: part_of GO:0033374 ! protein localization to T cell secretory granule + +[Term] +id: GO:0033377 +name: maintenance of protein location in T cell secretory granule +namespace: biological_process +def: "A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of protein localization in T cell secretory granule" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of protein localization in T lymphocyte secretory granule" EXACT [] +synonym: "maintenance of protein localization in T-cell secretory granule" EXACT [] +synonym: "maintenance of protein localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0032507 ! maintenance of protein location in cell +relationship: part_of GO:0033374 ! protein localization to T cell secretory granule + +[Term] +id: GO:0033378 +name: establishment of protease localization to T cell secretory granule +namespace: biological_process +def: "The directed movement of a protease to a location within a secretory granule in a T cell." [GOC:mah] +synonym: "establishment of protease localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "establishment of protease localization in T cell secretory granule" EXACT [] +synonym: "establishment of protease localization in T lymphocyte secretory granule" EXACT [] +synonym: "establishment of protease localization in T-cell secretory granule" EXACT [] +synonym: "establishment of protease localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033376 ! establishment of protein localization to T cell secretory granule +relationship: part_of GO:0033375 ! protease localization to T cell secretory granule + +[Term] +id: GO:0033379 +name: maintenance of protease location in T cell secretory granule +namespace: biological_process +def: "A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere." [GOC:dph, GOC:mah, GOC:tb] +synonym: "maintenance of protease localization in T cell secretory granule" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of protease localization in T lymphocyte secretory granule" EXACT [] +synonym: "maintenance of protease localization in T-cell secretory granule" EXACT [] +synonym: "maintenance of protease localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033377 ! maintenance of protein location in T cell secretory granule +relationship: part_of GO:0033375 ! protease localization to T cell secretory granule + +[Term] +id: GO:0033380 +name: granzyme B localization to T cell secretory granule +namespace: biological_process +def: "Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell." [GOC:mah] +synonym: "granzyme B localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "granzyme B localization in T cell secretory granule" EXACT [] +synonym: "granzyme B localization in T lymphocyte secretory granule" EXACT [] +synonym: "granzyme B localization in T-cell secretory granule" EXACT [] +synonym: "granzyme B localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033375 ! protease localization to T cell secretory granule + +[Term] +id: GO:0033381 +name: establishment of granzyme B localization to T cell secretory granule +namespace: biological_process +def: "The directed movement of the protease granzyme B to a location within a secretory granule in a T cell." [GOC:mah] +synonym: "establishment of granzyme B localisation in T cell secretory granule" EXACT [GOC:mah] +synonym: "establishment of granzyme B localization in T cell secretory granule" EXACT [] +synonym: "establishment of granzyme B localization in T lymphocyte secretory granule" EXACT [] +synonym: "establishment of granzyme B localization in T-cell secretory granule" EXACT [] +synonym: "establishment of granzyme B localization in T-lymphocyte secretory granule" EXACT [] +synonym: "T-lymphocyte secretory granule storage of granzyme B" RELATED [] +is_a: GO:0033378 ! establishment of protease localization to T cell secretory granule +relationship: part_of GO:0033380 ! granzyme B localization to T cell secretory granule + +[Term] +id: GO:0033382 +name: maintenance of granzyme B location in T cell secretory granule +namespace: biological_process +def: "A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere." [GOC:mah] +synonym: "maintenance of granzyme B localization in T cell secretory granule" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of granzyme B localization in T lymphocyte secretory granule" EXACT [] +synonym: "maintenance of granzyme B localization in T-cell secretory granule" EXACT [] +synonym: "maintenance of granzyme B localization in T-lymphocyte secretory granule" EXACT [] +is_a: GO:0033379 ! maintenance of protease location in T cell secretory granule +relationship: part_of GO:0033380 ! granzyme B localization to T cell secretory granule + +[Term] +id: GO:0033383 +name: geranyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes." [GOC:mah, MetaCyc:PWY-5122] +synonym: "geranyl diphosphate metabolism" EXACT [] +synonym: "geranyldiphosphate metabolic process" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0033384 +name: geranyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of geranyl diphosphate." [GOC:mah, MetaCyc:PWY-5122] +synonym: "geranyl diphosphate anabolism" EXACT [] +synonym: "geranyl diphosphate biosynthesis" EXACT [] +synonym: "geranyl diphosphate formation" EXACT [] +synonym: "geranyl diphosphate synthesis" EXACT [] +synonym: "geranyldiphosphate biosynthetic process" EXACT [] +xref: MetaCyc:PWY-5122 +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0033383 ! geranyl diphosphate metabolic process + +[Term] +id: GO:0033385 +name: geranylgeranyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins." [GOC:mah, MetaCyc:PWY-5120] +synonym: "geranylgeranyl diphosphate metabolism" EXACT [] +synonym: "geranylgeranyldiphosphate metabolic process" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0033386 +name: geranylgeranyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate." [GOC:mah, MetaCyc:PWY-5120] +synonym: "geranylgeranyl diphosphate anabolism" EXACT [] +synonym: "geranylgeranyl diphosphate biosynthesis" EXACT [] +synonym: "geranylgeranyl diphosphate formation" EXACT [] +synonym: "geranylgeranyl diphosphate synthesis" EXACT [] +xref: MetaCyc:PWY-5120 +xref: MetaCyc:PWY-5121 +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0033385 ! geranylgeranyl diphosphate metabolic process + +[Term] +id: GO:0033387 +name: putrescine biosynthetic process from ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine." [GOC:mah, MetaCyc:PWY-46] +synonym: "putrescine anabolism from ornithine" EXACT [] +synonym: "putrescine biosynthesis from ornithine" EXACT [] +synonym: "putrescine formation from ornithine" EXACT [] +synonym: "putrescine synthesis from ornithine" EXACT [] +is_a: GO:0006591 ! ornithine metabolic process +is_a: GO:0009446 ! putrescine biosynthetic process + +[Term] +id: GO:0033388 +name: putrescine biosynthetic process from arginine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine." [GOC:mah, MetaCyc:PWY-46] +synonym: "putrescine anabolism from arginine" EXACT [] +synonym: "putrescine biosynthesis from arginine" EXACT [] +synonym: "putrescine formation from arginine" EXACT [] +synonym: "putrescine synthesis from arginine" EXACT [] +is_a: GO:0006525 ! arginine metabolic process +is_a: GO:0009446 ! putrescine biosynthetic process + +[Term] +id: GO:0033389 +name: putrescine biosynthetic process from arginine, using agmatinase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step." [GOC:mah, MetaCyc:PWY-40] +synonym: "putrescine anabolism from arginine, using agmatinase" EXACT [] +synonym: "putrescine biosynthesis from arginine, using agmatinase" EXACT [] +synonym: "putrescine formation from arginine, using agmatinase" EXACT [] +synonym: "putrescine synthesis from arginine, using agmatinase" EXACT [] +is_a: GO:0033388 ! putrescine biosynthetic process from arginine + +[Term] +id: GO:0033390 +name: putrescine biosynthetic process from arginine via N-carbamoylputrescine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps." [GOC:mah, MetaCyc:PWY-43] +synonym: "putrescine anabolism from arginine via N-carbamoylputrescine" EXACT [] +synonym: "putrescine biosynthesis from arginine via N-carbamoylputrescine" EXACT [] +synonym: "putrescine formation from arginine via N-carbamoylputrescine" EXACT [] +synonym: "putrescine synthesis from arginine via N-carbamoylputrescine" EXACT [] +is_a: GO:0033388 ! putrescine biosynthetic process from arginine + +[Term] +id: GO:0033391 +name: chromatoid body +namespace: cellular_component +def: "A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182)." [PMID:17183363] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule + +[Term] +id: GO:0033392 +name: obsolete actin homodimerization activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an identical actin monomer to form a homodimer." [GOC:mah] +comment: This term was made obsolete because it was added in error; formation of an actin dimer is simply a transient step in the polymerization of actin. Also, this term may not represent a real molecular function in GO, but rather that a gene product (actin itself) is part of an actin homodimer transient protein complex. +synonym: "actin dimerization activity" BROAD [] +synonym: "actin homodimerization activity" EXACT [] +synonym: "actin polymerizing activity" RELATED [] +is_obsolete: true + +[Term] +id: GO:0033393 +name: homogalacturonan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3." [GOC:mah] +synonym: "homogalacturonan breakdown" EXACT [] +synonym: "homogalacturonan catabolism" EXACT [] +synonym: "homogalacturonan degradation" EXACT [] +xref: MetaCyc:PWY-1081 +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0010394 ! homogalacturonan metabolic process + +[Term] +id: GO:0033394 +name: beta-alanine biosynthetic process via 1,3 diaminopropane +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane." [GOC:mah, MetaCyc:PWY-3981] +synonym: "beta-alanine anabolism via 1,3 diaminopropane" EXACT [] +synonym: "beta-alanine biosynthesis via 1,3 diaminopropane" EXACT [] +synonym: "beta-alanine formation via 1,3 diaminopropane" EXACT [] +synonym: "beta-alanine synthesis via 1,3 diaminopropane" EXACT [] +xref: MetaCyc:PWY-3981 +is_a: GO:0019483 ! beta-alanine biosynthetic process + +[Term] +id: GO:0033395 +name: beta-alanine biosynthetic process via 3-hydroxypropionate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate." [GOC:mah, MetaCyc:PWY-3941] +synonym: "beta-alanine anabolism via 3-hydroxypropionate" EXACT [] +synonym: "beta-alanine biosynthesis via 3-hydroxypropionate" EXACT [] +synonym: "beta-alanine formation via 3-hydroxypropionate" EXACT [] +synonym: "beta-alanine synthesis via 3-hydroxypropionate" EXACT [] +xref: MetaCyc:PWY-3941 +is_a: GO:0019483 ! beta-alanine biosynthetic process + +[Term] +id: GO:0033396 +name: beta-alanine biosynthetic process via 3-ureidopropionate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate." [GOC:mah, MetaCyc:PWY-3982] +synonym: "beta-alanine anabolism via 3-ureidopropionate" EXACT [] +synonym: "beta-alanine formation via 3-ureidopropionate" EXACT [] +synonym: "beta-alanine synthesis via 3-ureidopropionate" EXACT [] +xref: MetaCyc:PWY-3982 +is_a: GO:0019483 ! beta-alanine biosynthetic process + +[Term] +id: GO:0033397 +name: zeatin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "zeatin metabolism" EXACT [] +is_a: GO:0009690 ! cytokinin metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0033398 +name: zeatin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "zeatin anabolism" EXACT [] +synonym: "zeatin biosynthesis" EXACT [] +synonym: "zeatin formation" EXACT [] +synonym: "zeatin synthesis" EXACT [] +is_a: GO:0009691 ! cytokinin biosynthetic process +is_a: GO:0033397 ! zeatin metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0033399 +name: cis-zeatin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "cis-zeatin metabolism" EXACT [] +is_a: GO:0033397 ! zeatin metabolic process + +[Term] +id: GO:0033400 +name: trans-zeatin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "trans-zeatin metabolism" EXACT [] +is_a: GO:0033397 ! zeatin metabolic process + +[Term] +id: GO:0033401 +name: UUU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UUU codon." [GOC:mah] +comment: Note that in the standard genetic code, TTT codes for phenylalanine. +synonym: "phenylalanine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TTT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033402 +name: UUC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UUC codon." [GOC:mah] +comment: Note that in the standard genetic code, TTC codes for phenylalanine. +synonym: "phenylalanine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TTC codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033403 +name: UUA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UUA codon." [GOC:mah] +comment: Note that in the standard genetic code, TTA codes for leucine. +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TTA codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033404 +name: UUG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UUG codon." [GOC:mah] +comment: Note that in the standard genetic code, TTG codes for leucine. +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TTG codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033405 +name: UCU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UCU codon." [GOC:mah] +comment: Note that in the standard genetic code, TCT codes for serine. +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TCT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033406 +name: UCC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UCC codon." [GOC:mah] +comment: Note that in the standard genetic code, TCC codes for serine. +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TCC codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033407 +name: UCA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UCA codon." [GOC:mah] +comment: Note that in the standard genetic code, TCA codes for serine. +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TCA codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033408 +name: UCG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UCG codon." [GOC:mah] +comment: Note that in the standard genetic code, TCG codes for serine. +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TCG codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033409 +name: UAU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UAU codon." [GOC:mah] +comment: Note that in the standard genetic code, TAT codes for tyrosine. +synonym: "TAT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "tyrosine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033410 +name: UAC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UAC codon." [GOC:mah] +comment: Note that in the standard genetic code, TAC codes for tyrosine. +synonym: "TAC codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "tyrosine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033411 +name: UAA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UAA codon." [GOC:mah] +comment: Note that in the standard genetic code, TAA is a stop codon (ochre) and is not normally read by a tRNA. +synonym: "TAA codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033412 +name: UAG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UAG codon." [GOC:mah] +comment: Note that in the standard genetic code, TAG is a stop codon (amber) and is not normally read by a tRNA. +synonym: "TAG codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033413 +name: UGU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UGU codon." [GOC:mah] +comment: Note that in the standard genetic code, TGT codes for cysteine. +synonym: "cysteine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TGT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033414 +name: UGC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UGC codon." [GOC:mah] +comment: Note that in the standard genetic code, TGC codes for cysteine. +synonym: "cysteine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "TGC codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033415 +name: UGA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UGA codon." [GOC:mah] +comment: Note that in the standard genetic code, TGA is a stop codon (opal) and is not normally read by a tRNA. +synonym: "TGA codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033416 +name: UGG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a UGG codon." [GOC:mah] +comment: Note that in the standard genetic code, TGG codes for tryptophan. +synonym: "TGG codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "tryptophan tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033417 +name: CUU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CUU codon." [GOC:mah] +comment: Note that in the standard genetic code, CTT codes for leucine. +synonym: "CTT codon-amino acid adaptor activity" EXACT [GOC:mah] +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033418 +name: CUC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CUC codon." [GOC:mah] +comment: Note that in the standard genetic code, CTC codes for leucine. +synonym: "CTC codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033419 +name: CUA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CUA codon." [GOC:mah] +comment: Note that in the standard genetic code, CTA codes for leucine. +synonym: "CTA codon-amino acid adaptor activity" EXACT [GOC:mah] +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033420 +name: CUG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CUG codon." [GOC:mah] +comment: Note that in the standard genetic code, CTG codes for leucine. +synonym: "CTG codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "leucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033421 +name: CCU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CCU codon." [GOC:mah] +comment: Note that in the standard genetic code, CCT codes for proline. +synonym: "CCT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "proline tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033422 +name: CCC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CCC codon." [GOC:mah] +comment: Note that in the standard genetic code, CCC codes for proline. +synonym: "proline tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033423 +name: CCA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CCA codon." [GOC:mah] +comment: Note that in the standard genetic code, CCA codes for proline. +synonym: "proline tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033424 +name: CCG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CCG codon." [GOC:mah] +comment: Note that in the standard genetic code, CCG codes for proline. +synonym: "proline tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033425 +name: CAU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CAU codon." [GOC:mah] +comment: Note that in the standard genetic code, CAT codes for histidine. +synonym: "CAT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "histidine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033426 +name: CAC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CAC codon." [GOC:mah] +comment: Note that in the standard genetic code, CAC codes for histidine. +synonym: "histidine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033427 +name: CAA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CAA codon." [GOC:mah] +comment: Note that in the standard genetic code, CAA codes for glutamine. +synonym: "glutamine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033428 +name: CAG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CAG codon." [GOC:mah] +comment: Note that in the standard genetic code, CAG codes for glutamine. +synonym: "glutamine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033429 +name: CGU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CGU codon." [GOC:mah] +comment: Note that in the standard genetic code, CGT codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "CGT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033430 +name: CGC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CGC codon." [GOC:mah] +comment: Note that in the standard genetic code, CGC codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033431 +name: CGA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CGA codon." [GOC:mah] +comment: Note that in the standard genetic code, CGA codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033432 +name: CGG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a CGG codon." [GOC:mah] +comment: Note that in the standard genetic code, CGG codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033433 +name: AUU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AUU codon." [GOC:mah] +comment: Note that in the standard genetic code, ATT codes for isoleucine. +synonym: "ATT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "isoleucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033434 +name: AUC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AUC codon." [GOC:mah] +comment: Note that in the standard genetic code, ATC codes for isoleucine. +synonym: "ATC codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "isoleucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033435 +name: AUA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AUA codon." [GOC:mah] +comment: Note that in the standard genetic code, ATA codes for isoleucine. +synonym: "ATA codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "isoleucine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033436 +name: AUG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AUG codon." [GOC:mah] +comment: Note that in the standard genetic code, ATG codes for methionine, and is the initiator codon. +synonym: "ATG codon-amino acid adaptor activity" EXACT [GOC:mah] +synonym: "initiator methionine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "methionine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033437 +name: ACU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an ACU codon." [GOC:mah] +comment: Note that in the standard genetic code, ACT codes for threonine. +synonym: "ACT codon-amino acid adaptor activity" EXACT [GOC:mah] +synonym: "threonine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033438 +name: ACC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an ACC codon." [GOC:mah] +comment: Note that in the standard genetic code, ACC codes for threonine. +synonym: "threonine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033439 +name: ACA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an ACA codon." [GOC:mah] +comment: Note that in the standard genetic code, ACA codes for threonine. +synonym: "threonine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033440 +name: ACG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an ACG codon." [GOC:mah] +comment: Note that in the standard genetic code, ACG codes for threonine. +synonym: "threonine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033441 +name: AAU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AAU codon." [GOC:mah] +comment: Note that in the standard genetic code, AAT codes for asparagine. +synonym: "AAT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "asparagine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033442 +name: AAC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AAC codon." [GOC:mah] +comment: Note that in the standard genetic code, AAC codes for asparagine. +synonym: "asparagine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033443 +name: AAA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AAA codon." [GOC:mah] +comment: Note that in the standard genetic code, AAA codes for lysine. +synonym: "lysine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033444 +name: AAG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AAG codon." [GOC:mah] +comment: Note that in the standard genetic code, AAG codes for lysine. +synonym: "lysine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033445 +name: AGU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AGU codon." [GOC:mah] +comment: Note that in the standard genetic code, AGT codes for serine. +synonym: "AGT codon-amino acid adaptor activity" EXACT [GOC:mah] +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033446 +name: AGC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AGC codon." [GOC:mah] +comment: Note that in the standard genetic code, AGC codes for serine. +synonym: "serine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033447 +name: AGA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AGA codon." [GOC:mah] +comment: Note that in the standard genetic code, AGA codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033448 +name: AGG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes an AGG codon." [GOC:mah] +comment: Note that in the standard genetic code, AGG codes for arginine. +synonym: "arginine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033449 +name: GUU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GUU codon." [GOC:mah] +comment: Note that in the standard genetic code, GTT codes for valine. +synonym: "GTT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "valine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033450 +name: GUC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GUC codon." [GOC:mah] +comment: Note that in the standard genetic code, GTC codes for valine. +synonym: "GTC codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "valine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033451 +name: GUA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GUA codon." [GOC:mah] +comment: Note that in the standard genetic code, GTA codes for valine. +synonym: "GTA codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "valine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033452 +name: GUG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GUG codon." [GOC:mah] +comment: Note that in the standard genetic code, GTG codes for valine. +synonym: "GTG codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "valine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033453 +name: GCU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GCU codon." [GOC:mah] +comment: Note that in the standard genetic code, GCT codes for alanine. +synonym: "alanine tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "GCT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033454 +name: GCC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GCC codon." [GOC:mah] +comment: Note that in the standard genetic code, GCC codes for alanine. +synonym: "alanine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033455 +name: GCA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GCA codon." [GOC:mah] +comment: Note that in the standard genetic code, GCA codes for alanine. +synonym: "alanine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033456 +name: GCG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GCG codon." [GOC:mah] +comment: Note that in the standard genetic code, GCG codes for alanine. +synonym: "alanine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033457 +name: GAU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GAU codon." [GOC:mah] +comment: Note that in the standard genetic code, GAT codes for aspartic acid. +synonym: "aspartic acid tRNA" RELATED [GOC:hjd, GOC:mah] +synonym: "GAT codon-amino acid adaptor activity" EXACT [GOC:hjd] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033458 +name: GAC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GAC codon." [GOC:mah] +comment: Note that in the standard genetic code, GAC codes for aspartic acid. +synonym: "aspartic acid tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033459 +name: GAA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GAA codon." [GOC:mah] +comment: Note that in the standard genetic code, GAA codes for glutamic acid. +synonym: "glutamic acid tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033460 +name: GAG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GAG codon." [GOC:mah] +comment: Note that in the standard genetic code, GAG codes for glutamic acid. +synonym: "glutamic acid tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033461 +name: GGU codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GGU codon." [GOC:mah] +comment: Note that in the standard genetic code, GGT codes for glycine. +synonym: "GGT codon-amino acid adaptor activity" EXACT [GOC:hjd] +synonym: "glycine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033462 +name: GGC codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GGC codon." [GOC:mah] +comment: Note that in the standard genetic code, GGC codes for glycine. +synonym: "glycine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033463 +name: GGA codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GGA codon." [GOC:mah] +comment: Note that in the standard genetic code, GGA codes for glycine. +synonym: "glycine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033464 +name: GGG codon-amino acid adaptor activity +namespace: molecular_function +def: "A triplet codon-amino acid adaptor activity that recognizes a GGG codon." [GOC:mah] +comment: Note that in the standard genetic code, GGG codes for glycine. +synonym: "glycine tRNA" RELATED [GOC:hjd, GOC:mah] +is_a: GO:0030533 ! triplet codon-amino acid adaptor activity + +[Term] +id: GO:0033465 +name: cis-zeatin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "cis-zeatin anabolism" EXACT [] +synonym: "cis-zeatin biosynthesis" EXACT [] +synonym: "cis-zeatin formation" EXACT [] +synonym: "cis-zeatin synthesis" EXACT [] +xref: MetaCyc:PWY-2781 +is_a: GO:0033398 ! zeatin biosynthetic process +is_a: GO:0033399 ! cis-zeatin metabolic process + +[Term] +id: GO:0033466 +name: trans-zeatin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol." [GOC:mah] +synonym: "trans-zeatin anabolism" EXACT [] +synonym: "trans-zeatin biosynthesis" EXACT [] +synonym: "trans-zeatin formation" EXACT [] +synonym: "trans-zeatin synthesis" EXACT [] +xref: MetaCyc:PWY-2681 +is_a: GO:0033398 ! zeatin biosynthetic process +is_a: GO:0033400 ! trans-zeatin metabolic process + +[Term] +id: GO:0033467 +name: CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate." [GOC:mah, MetaCyc:PWY-5111] +synonym: "CMP-KDO metabolic process" EXACT [] +synonym: "CMP-keto-3-deoxy-D-manno-octulosonic acid metabolism" EXACT [] +synonym: "CMP-ketodeoxyoctanoate metabolic process" RELATED [ISBN:0198506732] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033468 +name: CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate." [GOC:mah, MetaCyc:PWY-5111] +synonym: "CMP-KDO biosynthesis" EXACT [] +synonym: "CMP-KDO biosynthetic process" EXACT [] +synonym: "CMP-keto-3-deoxy-D-manno-octulosonic acid anabolism" EXACT [] +synonym: "CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthesis" EXACT [] +synonym: "CMP-keto-3-deoxy-D-manno-octulosonic acid formation" EXACT [] +synonym: "CMP-keto-3-deoxy-D-manno-octulosonic acid synthesis" EXACT [] +synonym: "CMP-ketodeoxyoctanoate biosynthetic process" RELATED [ISBN:0198506732] +xref: MetaCyc:KDOSYN-PWY +xref: MetaCyc:PWY-1269 +xref: MetaCyc:PWY-5111 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033467 ! CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process + +[Term] +id: GO:0033469 +name: gibberellin 12 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid." [GOC:mah] +synonym: "GA12 metabolic process" EXACT [] +synonym: "gibberellin 12 metabolism" EXACT [] +synonym: "gibberellin A12 metabolic process" EXACT [] +is_a: GO:0009685 ! gibberellin metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0033470 +name: gibberellin 12 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid." [GOC:mah] +synonym: "GA12 biosynthetic process" EXACT [] +synonym: "gibberellin 12 anabolism" EXACT [] +synonym: "gibberellin 12 biosynthesis" EXACT [] +synonym: "gibberellin 12 formation" EXACT [] +synonym: "gibberellin 12 synthesis" EXACT [] +synonym: "gibberellin A12 biosynthetic process" EXACT [] +xref: MetaCyc:PWY-5034 +is_a: GO:0009686 ! gibberellin biosynthetic process +is_a: GO:0033469 ! gibberellin 12 metabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0033471 +name: GDP-L-galactose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate." [GOC:mah] +synonym: "GDP-L-galactose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033472 +name: GDP-L-galactose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate." [GOC:mah] +synonym: "GDP-L-galactose anabolism" EXACT [] +synonym: "GDP-L-galactose biosynthesis" EXACT [] +synonym: "GDP-L-galactose formation" EXACT [] +synonym: "GDP-L-galactose synthesis" EXACT [] +xref: MetaCyc:PWY-5115 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033471 ! GDP-L-galactose metabolic process + +[Term] +id: GO:0033473 +name: indoleacetic acid conjugate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule." [GOC:mah] +synonym: "IAA conjugate metabolic process" EXACT [] +synonym: "indole acetic acid conjugate metabolic process" EXACT [] +synonym: "indole acetic acid conjugate metabolism" EXACT [] +synonym: "indoleacetic acid conjugate metabolism" EXACT [] +is_a: GO:0009683 ! indoleacetic acid metabolic process + +[Term] +id: GO:0033474 +name: indoleacetic acid conjugate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule." [GOC:mah] +synonym: "IAA conjugate biosynthetic process" EXACT [] +synonym: "indole acetic acid conjugate biosynthesis" EXACT [] +synonym: "indole acetic acid conjugate biosynthetic process" EXACT [] +synonym: "indoleacetic acid conjugate anabolism" EXACT [] +synonym: "indoleacetic acid conjugate biosynthesis" EXACT [] +synonym: "indoleacetic acid conjugate formation" EXACT [] +synonym: "indoleacetic acid conjugate synthesis" EXACT [] +is_a: GO:0009851 ! auxin biosynthetic process +is_a: GO:0033473 ! indoleacetic acid conjugate metabolic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process + +[Term] +id: GO:0033475 +name: indoleacetic acid amide conjugate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond." [GOC:mah, MetaCyc:PWY-1782] +synonym: "IAA amide conjugate biosynthetic process" EXACT [] +synonym: "indole acetic acid amide conjugate biosynthesis" EXACT [] +synonym: "indole acetic acid amide conjugate biosynthetic process" EXACT [] +synonym: "indoleacetic acid amide conjugate anabolism" EXACT [] +synonym: "indoleacetic acid amide conjugate biosynthesis" EXACT [] +synonym: "indoleacetic acid amide conjugate formation" EXACT [] +synonym: "indoleacetic acid amide conjugate synthesis" EXACT [] +xref: MetaCyc:PWY-1782 +is_a: GO:0033474 ! indoleacetic acid conjugate biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process + +[Term] +id: GO:0033476 +name: indoleacetic acid ester conjugate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond." [GOC:mah, MetaCyc:PWY-1741] +synonym: "IAA ester conjugate biosynthetic process" EXACT [] +synonym: "indole acetic acid ester conjugate biosynthesis" EXACT [] +synonym: "indole acetic acid ester conjugate biosynthetic process" EXACT [] +synonym: "indoleacetic acid ester conjugate anabolism" EXACT [] +synonym: "indoleacetic acid ester conjugate biosynthesis" EXACT [] +synonym: "indoleacetic acid ester conjugate formation" EXACT [] +synonym: "indoleacetic acid ester conjugate synthesis" EXACT [] +xref: MetaCyc:PWY-1741 +is_a: GO:0033474 ! indoleacetic acid conjugate biosynthetic process + +[Term] +id: GO:0033477 +name: S-methylmethionine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle." [GOC:mah, PMID:12692340] +synonym: "S-methylmethionine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0033478 +name: UDP-rhamnose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate." [GOC:mah, PMID:15134748] +synonym: "UDP-rhamnose metabolism" EXACT [] +xref: MetaCyc:PWY-3261 +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033479 +name: UDP-D-galacturonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate." [GOC:mah] +synonym: "UDP-D-galacturonate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0033480 +name: UDP-D-galacturonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate." [GOC:mah] +synonym: "UDP-D-galacturonate anabolism" EXACT [] +synonym: "UDP-D-galacturonate biosynthesis" EXACT [] +synonym: "UDP-D-galacturonate formation" EXACT [] +synonym: "UDP-D-galacturonate synthesis" EXACT [] +xref: MetaCyc:PWY-4 +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0033479 ! UDP-D-galacturonate metabolic process + +[Term] +id: GO:0033481 +name: galacturonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid." [GOC:mah] +synonym: "galacturonate anabolism" EXACT [] +synonym: "galacturonate biosynthesis" EXACT [] +synonym: "galacturonate formation" EXACT [] +synonym: "galacturonate synthesis" EXACT [] +is_a: GO:0019586 ! galacturonate metabolic process +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0033482 +name: D-galacturonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid." [GOC:jsg, GOC:mah] +synonym: "D-galacturonate anabolism" EXACT [] +synonym: "D-galacturonate biosynthesis" EXACT [] +synonym: "D-galacturonate formation" EXACT [] +synonym: "D-galacturonate synthesis" EXACT [] +is_a: GO:0033481 ! galacturonate biosynthetic process +is_a: GO:0046396 ! D-galacturonate metabolic process + +[Term] +id: GO:0033483 +name: gas homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell." [GOC:mah] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0033484 +name: nitric oxide homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell." [GOC:mah] +synonym: "NO homeostasis" EXACT [] +is_a: GO:0033483 ! gas homeostasis + +[Term] +id: GO:0033485 +name: cyanidin 3-O-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits." [GOC:mah, MetaCyc:PWY-5125] +synonym: "cyanidin 3-O-glucoside anabolism" EXACT [] +synonym: "cyanidin 3-O-glucoside biosynthesis" EXACT [] +synonym: "cyanidin 3-O-glucoside formation" EXACT [] +synonym: "cyanidin 3-O-glucoside synthesis" EXACT [] +xref: MetaCyc:PWY-5125 +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:1901038 ! cyanidin 3-O-glucoside metabolic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process + +[Term] +id: GO:0033486 +name: delphinidin 3-O-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits." [GOC:mah, MetaCyc:PWY-5153] +synonym: "delphinidin 3-O-glucoside anabolism" EXACT [] +synonym: "delphinidin 3-O-glucoside biosynthesis" EXACT [] +synonym: "delphinidin 3-O-glucoside formation" EXACT [] +synonym: "delphinidin 3-O-glucoside synthesis" EXACT [] +xref: MetaCyc:PWY-5153 +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process + +[Term] +id: GO:0033487 +name: pelargonidin 3-O-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits." [GOC:mah, MetaCyc:PWY-5125] +synonym: "pelargonidin 3-O-glucoside anabolism" EXACT [] +synonym: "pelargonidin 3-O-glucoside biosynthesis" EXACT [] +synonym: "pelargonidin 3-O-glucoside formation" EXACT [] +synonym: "pelargonidin 3-O-glucoside synthesis" EXACT [] +xref: MetaCyc:PWY-5125 +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process + +[Term] +id: GO:0033488 +name: cholesterol biosynthetic process via 24,25-dihydrolanosterol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol." [GOC:mah, MetaCyc:PWY66-3] +synonym: "cholesterol anabolism via 24,25-dihydrolanosterol" EXACT [] +synonym: "cholesterol biosynthesis via 24,25-dihydrolanosterol" EXACT [] +synonym: "cholesterol formation via 24,25-dihydrolanosterol" EXACT [] +synonym: "cholesterol synthesis via 24,25-dihydrolanosterol" EXACT [] +xref: MetaCyc:PWY66-3 +is_a: GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0033489 +name: cholesterol biosynthetic process via desmosterol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol." [GOC:mah, MetaCyc:PWY66-4] +synonym: "cholesterol anabolism via desmosterol" EXACT [] +synonym: "cholesterol biosynthesis via desmosterol" EXACT [] +synonym: "cholesterol formation via desmosterol" EXACT [] +synonym: "cholesterol synthesis via desmosterol" EXACT [] +xref: MetaCyc:PWY66-4 +is_a: GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0033490 +name: cholesterol biosynthetic process via lathosterol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol." [GOC:mah, MetaCyc:PWY66-341] +synonym: "cholesterol anabolism via lathosterol" EXACT [] +synonym: "cholesterol biosynthesis via lathosterol" EXACT [] +synonym: "cholesterol formation via lathosterol" EXACT [] +synonym: "cholesterol synthesis via lathosterol" EXACT [] +xref: MetaCyc:PWY66-341 +is_a: GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0033491 +name: coniferin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside." [GOC:mah, MetaCyc:PWY-116] +synonym: "coniferin metabolism" EXACT [] +xref: MetaCyc:PWY-116 +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process + +[Term] +id: GO:0033492 +name: esculetin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin." [GOC:mah] +synonym: "esculetin metabolism" EXACT [] +is_a: GO:0009804 ! coumarin metabolic process + +[Term] +id: GO:0033493 +name: esculetin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin." [GOC:mah] +synonym: "esculetin anabolism" EXACT [] +synonym: "esculetin biosynthesis" EXACT [] +synonym: "esculetin formation" EXACT [] +synonym: "esculetin synthesis" EXACT [] +xref: MetaCyc:PWY-5349 +is_a: GO:0009805 ! coumarin biosynthetic process +is_a: GO:0033492 ! esculetin metabolic process + +[Term] +id: GO:0033494 +name: ferulate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "ferulate metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0033495 +name: ferulate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "ferulate anabolism" EXACT [] +synonym: "ferulate biosynthesis" EXACT [] +synonym: "ferulate formation" EXACT [] +synonym: "ferulate synthesis" EXACT [] +xref: MetaCyc:PWY-5168 +is_a: GO:0033494 ! ferulate metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0033496 +name: sinapate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "sinapate metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0033497 +name: sinapate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "sinapate anabolism" EXACT [] +synonym: "sinapate biosynthesis" EXACT [] +synonym: "sinapate formation" EXACT [] +synonym: "sinapate synthesis" EXACT [] +xref: MetaCyc:PWY-5168 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0033496 ! sinapate metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0033498 +name: galactose catabolic process via D-galactonate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate." [GOC:mah, MetaCyc:GALDEG-PWY] +synonym: "galactose breakdown via D-galactonate" EXACT [] +synonym: "galactose catabolism via D-galactonate" EXACT [] +synonym: "galactose degradation via D-galactonate" EXACT [] +xref: MetaCyc:GALDEG-PWY +is_a: GO:0019388 ! galactose catabolic process + +[Term] +id: GO:0033499 +name: galactose catabolic process via UDP-galactose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose." [GOC:mah, MetaCyc:PWY-3821] +synonym: "galactose breakdown via UDP-galactose" EXACT [] +synonym: "galactose catabolism via UDP-galactose" EXACT [] +synonym: "galactose degradation via UDP-galactose" EXACT [] +synonym: "Leloir Pathway" RELATED [PMID:14741191] +xref: MetaCyc:PWY-3821 +is_a: GO:0019388 ! galactose catabolic process +property_value: RO:0002161 NCBITaxon:147554 + +[Term] +id: GO:0033500 +name: carbohydrate homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell." [GOC:mah] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0033501 +name: galactose homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell." [GOC:mah] +is_a: GO:0033500 ! carbohydrate homeostasis + +[Term] +id: GO:0033502 +name: cellular galactose homeostasis +namespace: biological_process +def: "A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment." [GOC:dph, GOC:mah, GOC:tb] +synonym: "cell galactose homeostasis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0033501 ! galactose homeostasis +is_a: GO:0055082 ! cellular chemical homeostasis + +[Term] +id: GO:0033503 +name: HULC complex +namespace: cellular_component +def: "A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2." [GOC:mah, PMID:17363370, PMID:17374714] +is_a: GO:0000151 ! ubiquitin ligase complex +is_a: GO:0031371 ! ubiquitin conjugating enzyme complex +relationship: part_of GO:0000792 ! heterochromatin + +[Term] +id: GO:0033504 +name: floor plate development +namespace: biological_process +def: "The progression of the floor plate over time from its initial formation until its mature state." [GOC:dh] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021915 ! neural tube development + +[Term] +id: GO:0033505 +name: floor plate morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the floor plate is generated and organized." [GOC:dh] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0033504 ! floor plate development + +[Term] +id: GO:0033506 +name: glucosinolate biosynthetic process from homomethionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine." [GOC:mah, MetaCyc:PWY-1187] +synonym: "glucosinolate anabolism from homomethionine" EXACT [] +synonym: "glucosinolate biosynthesis from homomethionine" EXACT [] +synonym: "glucosinolate formation from homomethionine" EXACT [] +synonym: "glucosinolate synthesis from homomethionine" EXACT [] +xref: MetaCyc:PWY-1187 +is_a: GO:0019761 ! glucosinolate biosynthetic process +is_a: GO:0033321 ! homomethionine metabolic process + +[Term] +id: GO:0033507 +name: glucosinolate biosynthetic process from phenylalanine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine." [GOC:mah, MetaCyc:PWY-2821] +synonym: "glucosinolate anabolism from phenylalanine" EXACT [] +synonym: "glucosinolate biosynthesis from phenylalanine" EXACT [] +synonym: "glucosinolate formation from phenylalanine" EXACT [] +synonym: "glucosinolate synthesis from phenylalanine" EXACT [] +xref: MetaCyc:PWY-2821 +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0019761 ! glucosinolate biosynthetic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0033508 +name: glutamate catabolic process to butyrate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate." [GOC:mah, MetaCyc:PWY-5087] +synonym: "glutamate breakdown to butyrate" EXACT [] +synonym: "glutamate degradation to butyrate" EXACT [] +xref: MetaCyc:PWY-5087 +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0019605 ! butyrate metabolic process + +[Term] +id: GO:0033509 +name: glutamate catabolic process to propionate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate." [GOC:mah, MetaCyc:PWY-5088] +synonym: "glutamate breakdown to propionate" EXACT [] +synonym: "glutamate degradation to propionate" EXACT [] +xref: MetaCyc:PWY-5088 +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0019541 ! propionate metabolic process + +[Term] +id: GO:0033510 +name: luteolin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one." [GOC:mah] +synonym: "luteolin metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0051552 ! flavone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0033511 +name: luteolin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one." [GOC:mah] +synonym: "luteolin anabolism" EXACT [] +synonym: "luteolin biosynthesis" EXACT [] +synonym: "luteolin formation" EXACT [] +synonym: "luteolin synthesis" EXACT [] +xref: MetaCyc:PWY-5060 +is_a: GO:0033510 ! luteolin metabolic process +is_a: GO:0051553 ! flavone biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0033512 +name: L-lysine catabolic process to acetyl-CoA via saccharopine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine." [GOC:mah, MetaCyc:LYSINE-DEG1-PWY] +synonym: "L-lysine breakdown to acetyl-CoA via saccharopine" EXACT [] +synonym: "L-lysine degradation to acetyl-CoA via saccharopine" EXACT [] +xref: MetaCyc:LYSINE-DEG1-PWY +is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA + +[Term] +id: GO:0033513 +name: L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide." [GOC:mah, MetaCyc:PWY-5280] +synonym: "L-lysine breakdown to acetyl-CoA via 5-aminopentanamide" EXACT [] +synonym: "L-lysine degradation to acetyl-CoA via 5-aminopentanamide" EXACT [] +xref: MetaCyc:PWY-5280 +is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA + +[Term] +id: GO:0033514 +name: L-lysine catabolic process to acetyl-CoA via L-pipecolate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate." [GOC:mah, MetaCyc:PWY-5283] +synonym: "L-lysine breakdown to acetyl-CoA via L-pipecolate" EXACT [] +synonym: "L-lysine degradation to acetyl-CoA via L-pipecolate" EXACT [] +xref: MetaCyc:PWY-5283 +is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA + +[Term] +id: GO:0033515 +name: L-lysine catabolic process using lysine 6-aminotransferase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase." [GOC:mah, MetaCyc:PWY-5298] +synonym: "L-lysine breakdown using lysine 6-aminotransferase" EXACT [GOC:mah] +synonym: "L-lysine degradation using lysine 6-aminotransferase" EXACT [GOC:mah] +xref: MetaCyc:PWY-5298 +is_a: GO:0019474 ! L-lysine catabolic process to acetyl-CoA + +[Term] +id: GO:0033516 +name: L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine." [GOC:mah, MetaCyc:PWY-702] +synonym: "L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +synonym: "methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine" EXACT [GOC:mah] +xref: MetaCyc:PWY-702 +is_a: GO:0019279 ! L-methionine biosynthetic process from L-homoserine via cystathionine + +[Term] +id: GO:0033517 +name: myo-inositol hexakisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds." [PMID:16107538] +synonym: "myo-inositol hexakisphosphate metabolism" EXACT [] +synonym: "phytate metabolic process" EXACT [] +synonym: "phytate metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043647 ! inositol phosphate metabolic process + +[Term] +id: GO:0033518 +name: myo-inositol hexakisphosphate dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate group from myo-inositol hexakisphosphate." [GOC:mah] +synonym: "phytate dephosphorylation" EXACT [] +xref: MetaCyc:PWY-4702 +xref: MetaCyc:PWY-4781 +is_a: GO:0033517 ! myo-inositol hexakisphosphate metabolic process +is_a: GO:0046855 ! inositol phosphate dephosphorylation + +[Term] +id: GO:0033519 +name: phytyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate." [GOC:mah] +synonym: "phytyl diphosphate metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0033520 +name: phytol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol." [GOC:mah] +synonym: "phytol anabolism" EXACT [] +synonym: "phytol biosynthesis" EXACT [] +synonym: "phytol formation" EXACT [] +synonym: "phytol synthesis" EXACT [] +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0033306 ! phytol metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:1903175 ! fatty alcohol biosynthetic process + +[Term] +id: GO:0033521 +name: phytyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate." [GOC:mah] +synonym: "phytyl diphosphate anabolism" EXACT [] +synonym: "phytyl diphosphate biosynthesis" EXACT [] +synonym: "phytyl diphosphate formation" EXACT [] +synonym: "phytyl diphosphate synthesis" EXACT [] +xref: MetaCyc:PWY-5063 +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0033519 ! phytyl diphosphate metabolic process + +[Term] +id: GO:0033522 +name: histone H2A ubiquitination +namespace: biological_process +def: "The modification of histone H2A by addition of one or more ubiquitin groups." [GOC:bf, GOC:mah, PMID:15509584, PMID:16473935, PMID:18430235] +is_a: GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0033523 +name: histone H2B ubiquitination +namespace: biological_process +def: "The modification of histone H2B by addition of ubiquitin groups." [GOC:mah] +is_a: GO:0016574 ! histone ubiquitination + +[Term] +id: GO:0033524 +name: sinapate ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "sinapate ester metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0033525 +name: sinapate ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate." [GOC:mah] +synonym: "sinapate ester anabolism" EXACT [] +synonym: "sinapate ester biosynthesis" EXACT [] +synonym: "sinapate ester formation" EXACT [] +synonym: "sinapate ester synthesis" EXACT [] +xref: MetaCyc:PWY-3301 +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0033524 ! sinapate ester metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0033526 +name: tetrapyrrole biosynthetic process from glutamate +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate." [GOC:mah, MetaCyc:PWY-5188] +synonym: "tetrapyrrole anabolism from glutamate" EXACT [] +synonym: "tetrapyrrole biosynthesis from glutamate" EXACT [] +synonym: "tetrapyrrole formation from glutamate" EXACT [] +synonym: "tetrapyrrole synthesis from glutamate" EXACT [] +xref: MetaCyc:PWY-5188 +is_a: GO:0006536 ! glutamate metabolic process +is_a: GO:0033014 ! tetrapyrrole biosynthetic process + +[Term] +id: GO:0033527 +name: tetrapyrrole biosynthetic process from glycine and succinyl-CoA +namespace: biological_process +def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA." [GOC:mah, MetaCyc:PWY-5189] +synonym: "tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [] +synonym: "tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [] +synonym: "tetrapyrrole formation from glycine and succinyl-CoA" EXACT [] +synonym: "tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [] +xref: MetaCyc:PWY-5189 +is_a: GO:0006104 ! succinyl-CoA metabolic process +is_a: GO:0006544 ! glycine metabolic process +is_a: GO:0033014 ! tetrapyrrole biosynthetic process + +[Term] +id: GO:0033528 +name: S-methylmethionine cycle +namespace: biological_process +def: "A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level." [GOC:mah, MetaCyc:PWY-5441] +xref: MetaCyc:PWY-5441 +is_a: GO:0033477 ! S-methylmethionine metabolic process + +[Term] +id: GO:0033529 +name: raffinose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah] +synonym: "raffinose anabolism" EXACT [] +synonym: "raffinose biosynthesis" EXACT [] +synonym: "raffinose formation" EXACT [] +synonym: "raffinose synthesis" EXACT [] +is_a: GO:0010325 ! raffinose family oligosaccharide biosynthetic process +is_a: GO:0033530 ! raffinose metabolic process + +[Term] +id: GO:0033530 +name: raffinose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah] +synonym: "raffinose metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process + +[Term] +id: GO:0033531 +name: stachyose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah] +synonym: "stachyose metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process + +[Term] +id: GO:0033532 +name: stachyose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah] +synonym: "stachyose anabolism" EXACT [] +synonym: "stachyose biosynthesis" EXACT [] +synonym: "stachyose formation" EXACT [] +synonym: "stachyose synthesis" EXACT [] +xref: MetaCyc:PWY-5337 +is_a: GO:0010325 ! raffinose family oligosaccharide biosynthetic process +is_a: GO:0033531 ! stachyose metabolic process + +[Term] +id: GO:0033533 +name: verbascose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah, MetaCyc:CPD-8065] +synonym: "verbascose metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process + +[Term] +id: GO:0033534 +name: verbascose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah, MetaCyc:CPD-8065] +synonym: "verbascose anabolism" EXACT [] +synonym: "verbascose biosynthesis" EXACT [] +synonym: "verbascose formation" EXACT [] +synonym: "verbascose synthesis" EXACT [] +is_a: GO:0010325 ! raffinose family oligosaccharide biosynthetic process +is_a: GO:0033533 ! verbascose metabolic process + +[Term] +id: GO:0033535 +name: ajugose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah, MetaCyc:CPD-8066] +synonym: "ajugose metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process + +[Term] +id: GO:0033536 +name: ajugose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah, MetaCyc:CPD-8066] +synonym: "ajugose anabolism" EXACT [] +synonym: "ajugose biosynthesis" EXACT [] +synonym: "ajugose formation" EXACT [] +synonym: "ajugose synthesis" EXACT [] +is_a: GO:0010325 ! raffinose family oligosaccharide biosynthetic process +is_a: GO:0033535 ! ajugose metabolic process + +[Term] +id: GO:0033537 +name: ajugose biosynthetic process using galactinol:raffinose galactosyltransferase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide." [GOC:mah, MetaCyc:PWY-5342] +synonym: "ajugose anabolism using galactinol:raffinose galactosyltransferase" EXACT [] +synonym: "ajugose biosynthesis using galactinol:raffinose galactosyltransferase" EXACT [] +synonym: "ajugose formation using galactinol:raffinose galactosyltransferase" EXACT [] +synonym: "ajugose synthesis using galactinol:raffinose galactosyltransferase" EXACT [] +xref: MetaCyc:PWY-5342 +is_a: GO:0033536 ! ajugose biosynthetic process + +[Term] +id: GO:0033538 +name: ajugose biosynthetic process using galactan:galactan galactosyltransferase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another." [GOC:mah, MetaCyc:PWY-5343] +synonym: "ajugose anabolism using galactan:galactan galactosyltransferase" EXACT [] +synonym: "ajugose biosynthesis using galactan:galactan galactosyltransferase" EXACT [] +synonym: "ajugose formation using galactan:galactan galactosyltransferase" EXACT [] +synonym: "ajugose synthesis using galactan:galactan galactosyltransferase" EXACT [] +xref: MetaCyc:PWY-5343 +is_a: GO:0033536 ! ajugose biosynthetic process + +[Term] +id: GO:0033539 +name: fatty acid beta-oxidation using acyl-CoA dehydrogenase +namespace: biological_process +def: "A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:FAO-PWY, MetaCyc:PWY-5136] +xref: MetaCyc:FAO-PWY +is_a: GO:0006635 ! fatty acid beta-oxidation +relationship: has_part GO:0003995 ! acyl-CoA dehydrogenase activity + +[Term] +id: GO:0033540 +name: fatty acid beta-oxidation using acyl-CoA oxidase +namespace: biological_process +def: "A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:PWY-5136] +xref: MetaCyc:PWY-5136 +is_a: GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0033541 +name: fatty acid beta-oxidation, unsaturated, odd number +namespace: biological_process +def: "A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:PWY-5137] +xref: MetaCyc:PWY-5137 +is_a: GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0033542 +name: fatty acid beta-oxidation, unsaturated, even number +namespace: biological_process +def: "A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:PWY-5138] +xref: MetaCyc:PWY-5138 +is_a: GO:0006635 ! fatty acid beta-oxidation + +[Term] +id: GO:0033543 +name: fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway +namespace: biological_process +def: "A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:PWY-5138] +is_a: GO:0033542 ! fatty acid beta-oxidation, unsaturated, even number + +[Term] +id: GO:0033544 +name: fatty acid beta-oxidation, unsaturated, even number, epimerase pathway +namespace: biological_process +def: "A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:mah, MetaCyc:PWY-5138] +is_a: GO:0033542 ! fatty acid beta-oxidation, unsaturated, even number + +[Term] +id: GO:0033545 +name: myo-inositol hexakisphosphate biosynthetic process, lipid-dependent +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C." [GOC:mah, MetaCyc:PWY-6555] +synonym: "myo-inositol hexakisphosphate anabolism, lipid-dependent" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthesis, lipid-dependent" EXACT [] +synonym: "myo-inositol hexakisphosphate formation, lipid-dependent" EXACT [] +synonym: "myo-inositol hexakisphosphate synthesis, lipid-dependent" EXACT [] +synonym: "phytate biosynthesis, lipid-dependent" EXACT [] +synonym: "phytate biosynthetic process, lipid-dependent" EXACT [] +xref: MetaCyc:PWY-6555 +is_a: GO:0010264 ! myo-inositol hexakisphosphate biosynthetic process + +[Term] +id: GO:0033546 +name: myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further." [GOC:mah, MetaCyc:PWY-6554] +synonym: "myo-inositol hexakisphosphate anabolism, via inositol 1,3,4-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthesis, via inositol 1,3,4-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate formation, via inositol 1,3,4-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate synthesis, via inositol 1,3,4-trisphosphate" EXACT [] +synonym: "phytate biosynthesis, via inositol 1,3,4-trisphosphate" EXACT [] +synonym: "phytate biosynthetic process, via inositol 1,3,4-trisphosphate" EXACT [] +xref: MetaCyc:PWY-6554 +is_a: GO:0033545 ! myo-inositol hexakisphosphate biosynthetic process, lipid-dependent + +[Term] +id: GO:0033547 +name: obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate." [GOC:mah, MetaCyc:PWY-4541] +comment: This term was made obsolete because its only cross-reference points to a MetaCyc entry (PWY-4541) that was deleted from the MetaCyc database. +synonym: "myo-inositol hexakisphosphate anabolism, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate formation, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "myo-inositol hexakisphosphate synthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "phytate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +synonym: "phytate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate" EXACT [] +xref: MetaCyc:PWY-4541 +is_obsolete: true + +[Term] +id: GO:0033548 +name: myo-inositol hexakisphosphate biosynthetic process, lipid-independent +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate." [GOC:mah, MetaCyc:PWY-4661] +synonym: "myo-inositol hexakisphosphate anabolism, lipid-independent" EXACT [] +synonym: "myo-inositol hexakisphosphate biosynthesis, lipid-independent" EXACT [] +synonym: "myo-inositol hexakisphosphate formation, lipid-independent" EXACT [] +synonym: "myo-inositol hexakisphosphate synthesis, lipid-independent" EXACT [] +synonym: "phytate biosynthesis, lipid-independent" EXACT [] +synonym: "phytate biosynthetic process, lipid-independent" EXACT [] +xref: MetaCyc:PWY-4661 +is_a: GO:0010264 ! myo-inositol hexakisphosphate biosynthetic process + +[Term] +id: GO:0033549 +name: MAP kinase phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate." [GOC:mah, PMID:12184814, PMID:17208316] +synonym: "MAPK phosphatase activity" EXACT [PMID:12184814] +is_a: GO:0004721 ! phosphoprotein phosphatase activity +relationship: part_of GO:0000188 ! inactivation of MAPK activity + +[Term] +id: GO:0033550 +name: MAP kinase tyrosine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate." [GOC:mah] +synonym: "tyrosine-specific MAP kinase phosphatase activity" EXACT [] +is_a: GO:0004725 ! protein tyrosine phosphatase activity +is_a: GO:0033549 ! MAP kinase phosphatase activity +relationship: part_of GO:1990264 ! peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity + +[Term] +id: GO:0033551 +name: monopolin complex +namespace: cellular_component +def: "A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits." [GOC:mah, GOC:rb, PMID:17627824] +synonym: "monopolin subcomplex Csm1/Lrs4" NARROW [] +synonym: "Pcs1/Mde4 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000777 ! condensed chromosome kinetochore + +[Term] +id: GO:0033552 +name: response to vitamin B3 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus." [GOC:sl] +synonym: "response to niacin" NARROW [] +synonym: "response to nicotinamide" NARROW [] +is_a: GO:0033273 ! response to vitamin + +[Term] +id: GO:0033553 +name: rDNA heterochromatin +namespace: cellular_component +def: "A region of heterochromatin located at the rDNA repeats in a chromosome." [GOC:mah] +synonym: "ribosomal DNA heterochromatin" EXACT [] +is_a: GO:0000792 ! heterochromatin + +[Term] +id: GO:0033554 +name: cellular response to stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0006950 ! response to stress +is_a: GO:0051716 ! cellular response to stimulus + +[Term] +id: GO:0033555 +name: multicellular organismal response to stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] +is_a: GO:0006950 ! response to stress +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0033556 +name: dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol." [GOC:mah, PMID:10336995] +synonym: "dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033557 +name: Slx1-Slx4 complex +namespace: cellular_component +def: "A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes." [PMID:14528010, PMID:16467377] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0033558 +name: protein deacetylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate." [GOC:mah] +xref: Reactome:R-HSA-5693092 "Unknown deacetylase deacetylates 7K-BACE1(46-501)" +xref: Reactome:R-HSA-8952069 "HDAC4 deacetylates RUNX3" +xref: Reactome:R-HSA-9626962 "SIRT1 deacetylates FOXO1" +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006476 ! protein deacetylation + +[Term] +id: GO:0033559 +name: unsaturated fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms." [GOC:mah] +synonym: "unsaturated fatty acid metabolism" EXACT [] +xref: MetaCyc:PWY-762 +xref: MetaCyc:PWY-782 +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0033560 +name: folate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+." [GOC:pde] +xref: Reactome:R-HSA-197963 "Folate is reduced to dihydrofolate (DHF)" +xref: Reactome:R-HSA-197972 "DHF is reduced to tetrahydrofolate (THF)" +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033561 +name: regulation of water loss via skin +namespace: biological_process +def: "A process that modulates the rate or extent of water loss from an organism via the skin." [GOC:mah] +synonym: "skin barrier function" RELATED [] +is_a: GO:0050891 ! multicellular organismal water homeostasis + +[Term] +id: GO:0033562 +name: co-transcriptional gene silencing by RNA interference machinery +namespace: biological_process +def: "A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin." [GOC:mah, GOC:vw, PMID:17512405, PMID:21151114, PMID:22431512] +synonym: "co-transcriptional gene silencing by small RNA" EXACT [GOC:vw] +synonym: "cotranscriptional gene silencing by RNA interference machinery" RELATED [] +synonym: "cotranscriptional gene silencing by small RNA" RELATED [] +synonym: "RNAi-mediated CTGS" EXACT [GOC:vw] +synonym: "small RNA-mediated cotranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031047 ! gene silencing by RNA + +[Term] +id: GO:0033563 +name: dorsal/ventral axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:kmv, GOC:tb] +synonym: "dorsal-ventral axon guidance" EXACT [GOC:mah] +synonym: "dorsal/ventral axon pathfinding" EXACT [GOC:mah] +synonym: "dorsoventral axon guidance" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance + +[Term] +id: GO:0033564 +name: anterior/posterior axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:kmv, GOC:tb] +synonym: "anterior-posterior axon guidance" EXACT [] +synonym: "anterior/posterior axon pathfinding" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance + +[Term] +id: GO:0033565 +name: ESCRT-0 complex +namespace: cellular_component +def: "A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals." [GOC:rb, PMID:12055639, PMID:17543868] +synonym: "Hrs/STAM complex" EXACT [] +synonym: "Vps27p-Hse1p complex" EXACT [] +is_a: GO:0036452 ! ESCRT complex + +[Term] +id: GO:0033566 +name: gamma-tubulin complex localization +namespace: biological_process +def: "Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of gamma-tubulin complex localization" EXACT [] +synonym: "gamma-tubulin complex localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization + +[Term] +id: GO:0033567 +name: DNA replication, Okazaki fragment processing +namespace: biological_process +def: "The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand." [GOC:mah, ISBN:0716720094] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006273 ! lagging strand elongation + +[Term] +id: GO:0033568 +name: lactoferrin receptor activity +namespace: molecular_function +def: "Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH." [GOC:bf, GOC:mlg, PMID:16261254] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0033569 +name: lactoferrin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lactoferrin from one side of a membrane to the other." [GOC:mlg] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0033571 ! lactoferrin transport + +[Term] +id: GO:0033570 +name: obsolete transferrin transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of transferrin from one side of a membrane to the other." [GOC:mlg] +comment: This term was obsoleted because there is no evidence that this function exists. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17157 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0033571 +name: lactoferrin transport +namespace: biological_process +def: "The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mlg] +is_a: GO:0006826 ! iron ion transport +is_a: GO:0015031 ! protein transport + +[Term] +id: GO:0033572 +name: transferrin transport +namespace: biological_process +def: "The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mlg] +synonym: "melanotransferrin transport" EXACT [PR:000001887] +is_a: GO:0006826 ! iron ion transport +is_a: GO:0015031 ! protein transport + +[Term] +id: GO:0033573 +name: high-affinity iron permease complex +namespace: cellular_component +def: "A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:jp, PMID:16522632, PMID:8599111] +synonym: "high affinity iron permease complex" EXACT [] +xref: IntAct:EBI-12592666 +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1902495 ! transmembrane transporter complex +is_a: GO:1905862 ! ferroxidase complex + +[Term] +id: GO:0033574 +name: response to testosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus." [GOC:sl] +synonym: "response to testosterone stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0033575 +name: protein glycosylation at cell surface +namespace: biological_process +def: "The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell." [GOC:mah, GOC:pr, PMID:12042244] +synonym: "protein amino acid glycosylation at cell surface" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0033576 +name: protein glycosylation in cytosol +namespace: biological_process +def: "The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol." [GOC:mah, GOC:pr, PMID:12042244] +synonym: "protein amino acid glycosylation in cytosol" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation +intersection_of: GO:0006486 ! protein glycosylation +intersection_of: occurs_in GO:0005829 ! cytosol +relationship: occurs_in GO:0005829 ! cytosol + +[Term] +id: GO:0033577 +name: protein glycosylation in endoplasmic reticulum +namespace: biological_process +def: "The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum." [GOC:mah, GOC:pr, PMID:12042244] +synonym: "core glycosylation" RELATED [PMID:6345657] +synonym: "protein amino acid glycosylation in endoplasmic reticulum" EXACT [GOC:bf] +synonym: "protein amino acid glycosylation in ER" EXACT [] +is_a: GO:0006486 ! protein glycosylation +intersection_of: GO:0006486 ! protein glycosylation +intersection_of: occurs_in GO:0005783 ! endoplasmic reticulum +relationship: occurs_in GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0033578 +name: protein glycosylation in Golgi +namespace: biological_process +def: "The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus." [GOC:mah, GOC:pr, PMID:12042244] +synonym: "protein amino acid glycosylation in Golgi" EXACT [GOC:bf] +synonym: "terminal glycosylation" NARROW [PMID:6345657] +is_a: GO:0006486 ! protein glycosylation +intersection_of: GO:0006486 ! protein glycosylation +intersection_of: occurs_in GO:0005794 ! Golgi apparatus +relationship: occurs_in GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0033579 +name: protein galactosylation in endoplasmic reticulum +namespace: biological_process +def: "The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum." [GOC:mah] +synonym: "protein amino acid galactosylation in endoplasmic reticulum" EXACT [GOC:bf] +synonym: "protein amino acid galactosylation in ER" EXACT [] +is_a: GO:0033577 ! protein glycosylation in endoplasmic reticulum +is_a: GO:0042125 ! protein galactosylation +intersection_of: GO:0042125 ! protein galactosylation +intersection_of: occurs_in GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0033580 +name: protein galactosylation at cell surface +namespace: biological_process +def: "The addition of a galactose unit to a protein amino acid at the surface of a cell." [GOC:mah] +synonym: "protein amino acid galactosylation at cell surface" EXACT [GOC:bf] +is_a: GO:0033575 ! protein glycosylation at cell surface +is_a: GO:0042125 ! protein galactosylation + +[Term] +id: GO:0033581 +name: protein galactosylation in Golgi +namespace: biological_process +def: "The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus." [GOC:mah] +synonym: "protein amino acid galactosylation in Golgi" EXACT [GOC:bf] +is_a: GO:0033578 ! protein glycosylation in Golgi +is_a: GO:0042125 ! protein galactosylation +intersection_of: GO:0042125 ! protein galactosylation +intersection_of: occurs_in GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0033582 +name: protein galactosylation in cytosol +namespace: biological_process +def: "The addition of a galactose unit to a protein amino acid in the cytosol." [GOC:mah] +synonym: "protein amino acid galactosylation in cytosol" EXACT [GOC:bf] +is_a: GO:0033576 ! protein glycosylation in cytosol +is_a: GO:0042125 ! protein galactosylation +intersection_of: GO:0042125 ! protein galactosylation +intersection_of: occurs_in GO:0005829 ! cytosol + +[Term] +id: GO:0033583 +name: rhabdomere membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding the rhabdomere." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0016028 ! rhabdomere + +[Term] +id: GO:0033584 +name: tyrosine biosynthetic process from chorismate via L-arogenate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate." [GOC:mah, MetaCyc:PWY-3461] +synonym: "tyrosine anabolism from chorismate via L-arogenate" EXACT [] +synonym: "tyrosine formation from chorismate via L-arogenate" EXACT [] +synonym: "tyrosine synthesis from chorismate via L-arogenate" EXACT [] +xref: MetaCyc:PWY-3461 +is_a: GO:0006571 ! tyrosine biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0033585 +name: L-phenylalanine biosynthetic process from chorismate via phenylpyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate." [GOC:go_curators] +synonym: "L-phenylalanine anabolism from chorismate via phenylpyruvate" EXACT [] +synonym: "L-phenylalanine biosynthesis from chorismate via phenylpyruvate" EXACT [] +synonym: "L-phenylalanine formation from chorismate via phenylpyruvate" EXACT [] +synonym: "L-phenylalanine synthesis from chorismate via phenylpyruvate" EXACT [] +xref: MetaCyc:PHESYN +is_a: GO:0009094 ! L-phenylalanine biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0033586 +name: L-phenylalanine biosynthetic process from chorismate via L-arogenate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate." [GOC:go_curators] +synonym: "L-phenylalanine anabolism from chorismate via L-arogenate" EXACT [] +synonym: "L-phenylalanine biosynthesis from chorismate via L-arogenate" EXACT [] +synonym: "L-phenylalanine formation from chorismate via L-arogenate" EXACT [] +synonym: "L-phenylalanine synthesis from chorismate via L-arogenate" EXACT [] +xref: MetaCyc:PWY-3462 +is_a: GO:0009094 ! L-phenylalanine biosynthetic process +is_a: GO:0046417 ! chorismate metabolic process + +[Term] +id: GO:0033587 +name: shikimate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid." [GOC:mah] +synonym: "shikimate anabolism" EXACT [] +synonym: "shikimate biosynthesis" EXACT [] +synonym: "shikimate formation" EXACT [] +synonym: "shikimate synthesis" EXACT [] +is_a: GO:0019632 ! shikimate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0033588 +name: Elongator holoenzyme complex +namespace: cellular_component +alt_id: GO:0033589 +def: "A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes." [GOC:bhm, GOC:jh, GOC:mah, GOC:vw, PMID:11435442, PMID:11689709, PMID:15769872, PMID:17018299, PMID:18755837, PMID:23165209] +comment: Despite its name, this complex is no longer thought to be directly involved in transcriptional elongation (PMID:23165209). +synonym: "Elongator core complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0033590 +name: response to cobalamin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus." [GOC:sl] +synonym: "response to vitamin B12" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0033591 +name: response to L-ascorbic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus." [GOC:sl] +synonym: "response to ascorbic acid" BROAD [] +synonym: "response to L-ascorbate" EXACT [] +synonym: "response to vitamin C" EXACT [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0033273 ! response to vitamin +is_a: GO:0034284 ! response to monosaccharide + +[Term] +id: GO:0033592 +name: RNA strand annealing activity +namespace: molecular_function +def: "Facilitates the base-pairing of complementary single-stranded RNA." [GOC:mah] +is_a: GO:0003725 ! double-stranded RNA binding +is_a: GO:0003727 ! single-stranded RNA binding +is_a: GO:0097617 ! annealing activity + +[Term] +id: GO:0033593 +name: BRCA2-MAGE-D1 complex +namespace: cellular_component +def: "A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth." [PMID:15930293] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0033594 +name: response to hydroxyisoflavone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus." [GOC:mah] +is_a: GO:0080184 ! response to phenylpropanoid +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0033595 +name: response to genistein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus." [GOC:mah] +is_a: GO:0009725 ! response to hormone +is_a: GO:0033594 ! response to hydroxyisoflavone +is_a: GO:0097327 ! response to antineoplastic agent + +[Term] +id: GO:0033596 +name: TSC1-TSC2 complex +namespace: cellular_component +def: "A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway." [PMID:10585443, PMID:17121544, PMID:9580671] +synonym: "tuberin-hamartin complex" EXACT [] +synonym: "tuberous sclerosis complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0033597 +name: mitotic checkpoint complex +namespace: cellular_component +def: "A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20." [PMID:10704439, PMID:11535616, PMID:11726501, PMID:17650307] +synonym: "MCC" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990298 ! bub1-bub3 complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033598 +name: mammary gland epithelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, GOC:mah] +is_a: GO:0050673 ! epithelial cell proliferation +relationship: part_of GO:0061180 ! mammary gland epithelium development + +[Term] +id: GO:0033599 +name: regulation of mammary gland epithelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033598 ! mammary gland epithelial cell proliferation +relationship: regulates GO:0033598 ! mammary gland epithelial cell proliferation + +[Term] +id: GO:0033600 +name: negative regulation of mammary gland epithelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] +synonym: "down regulation of mammary gland epithelial cell proliferation" EXACT [] +synonym: "down-regulation of mammary gland epithelial cell proliferation" EXACT [] +synonym: "downregulation of mammary gland epithelial cell proliferation" EXACT [] +synonym: "inhibition of mammary gland epithelial cell proliferation" NARROW [] +is_a: GO:0033599 ! regulation of mammary gland epithelial cell proliferation +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033598 ! mammary gland epithelial cell proliferation +relationship: negatively_regulates GO:0033598 ! mammary gland epithelial cell proliferation + +[Term] +id: GO:0033601 +name: positive regulation of mammary gland epithelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] +synonym: "activation of mammary gland epithelial cell proliferation" NARROW [] +synonym: "stimulation of mammary gland epithelial cell proliferation" NARROW [] +synonym: "up regulation of mammary gland epithelial cell proliferation" EXACT [] +synonym: "up-regulation of mammary gland epithelial cell proliferation" EXACT [] +synonym: "upregulation of mammary gland epithelial cell proliferation" EXACT [] +is_a: GO:0033599 ! regulation of mammary gland epithelial cell proliferation +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033598 ! mammary gland epithelial cell proliferation +relationship: positively_regulates GO:0033598 ! mammary gland epithelial cell proliferation + +[Term] +id: GO:0033602 +name: negative regulation of dopamine secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine." [GOC:sl] +synonym: "down regulation of dopamine secretion" EXACT [] +synonym: "down-regulation of dopamine secretion" EXACT [] +synonym: "downregulation of dopamine secretion" EXACT [] +synonym: "inhibition of dopamine secretion" NARROW [] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0014059 ! regulation of dopamine secretion +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0033604 ! negative regulation of catecholamine secretion +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014046 ! dopamine secretion +relationship: negatively_regulates GO:0014046 ! dopamine secretion + +[Term] +id: GO:0033603 +name: positive regulation of dopamine secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine." [GOC:sl] +synonym: "activation of dopamine secretion" NARROW [] +synonym: "stimulation of dopamine secretion" NARROW [] +synonym: "up regulation of dopamine secretion" EXACT [] +synonym: "up-regulation of dopamine secretion" EXACT [] +synonym: "upregulation of dopamine secretion" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0014059 ! regulation of dopamine secretion +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0033605 ! positive regulation of catecholamine secretion +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014046 ! dopamine secretion +relationship: positively_regulates GO:0014046 ! dopamine secretion + +[Term] +id: GO:0033604 +name: negative regulation of catecholamine secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] +synonym: "down regulation of catecholamine secretion" EXACT [] +synonym: "down-regulation of catecholamine secretion" EXACT [] +synonym: "downregulation of catecholamine secretion" EXACT [] +synonym: "inhibition of catecholamine secretion" NARROW [] +is_a: GO:0050433 ! regulation of catecholamine secretion +is_a: GO:0051953 ! negative regulation of amine transport +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050432 ! catecholamine secretion +relationship: negatively_regulates GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0033605 +name: positive regulation of catecholamine secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] +synonym: "activation of catecholamine secretion" NARROW [] +synonym: "stimulation of catecholamine secretion" NARROW [] +synonym: "up regulation of catecholamine secretion" EXACT [] +synonym: "up-regulation of catecholamine secretion" EXACT [] +synonym: "upregulation of catecholamine secretion" EXACT [] +is_a: GO:0050433 ! regulation of catecholamine secretion +is_a: GO:0051954 ! positive regulation of amine transport +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050432 ! catecholamine secretion +relationship: positively_regulates GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0033606 +name: chemokine receptor transport within lipid bilayer +namespace: biological_process +def: "The directed movement of a chemokine receptor within a lipid bilayer." [GOC:mah] +synonym: "chemokine receptor translocation within membrane" EXACT [] +is_a: GO:0032594 ! protein transport within lipid bilayer + +[Term] +id: GO:0033607 +name: SOD1-Bcl-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway." [PMID:15233914, PMID:16790527] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0033608 +name: formyl-CoA transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA." [EC:2.8.3.16, RHEA:16545] +synonym: "formyl-CoA oxalate CoA-transferase activity" EXACT [EC:2.8.3.16] +synonym: "formyl-CoA:oxalate CoA-transferase activity" EXACT [EC:2.8.3.16] +synonym: "formyl-coenzyme A transferase activity" EXACT [EC:2.8.3.16] +xref: EC:2.8.3.16 +xref: KEGG_REACTION:R07290 +xref: MetaCyc:RXN0-1382 +xref: RHEA:16545 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0033609 +name: oxalate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oxalate, the organic acid ethanedioate." [GOC:mlg] +synonym: "ethanedioate metabolic process" EXACT [] +synonym: "ethanedioic acid metabolic process" EXACT [] +synonym: "oxalate metabolism" EXACT [] +synonym: "oxalic acid metabolic process" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0033610 +name: oxalate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate." [GOC:mlg] +synonym: "ethanedioate biosynthetic process" EXACT [] +synonym: "ethanedioic acid biosynthetic process" EXACT [] +synonym: "oxalate anabolism" EXACT [] +synonym: "oxalate biosynthesis" EXACT [] +synonym: "oxalate formation" EXACT [] +synonym: "oxalate synthesis" EXACT [] +synonym: "oxalic acid biosynthetic process" EXACT [] +is_a: GO:0033609 ! oxalate metabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process + +[Term] +id: GO:0033611 +name: oxalate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate." [GOC:mlg] +synonym: "ethanedioate catabolic process" EXACT [] +synonym: "ethanedioic acid catabolic process" EXACT [] +synonym: "oxalate breakdown" EXACT [] +synonym: "oxalate catabolism" EXACT [] +synonym: "oxalate degradation" EXACT [] +synonym: "oxalic acid catabolic process" EXACT [] +is_a: GO:0033609 ! oxalate metabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process + +[Term] +id: GO:0033612 +name: receptor serine/threonine kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity." [GOC:mah] +synonym: "transmembrane receptor protein serine/threonine kinase ligand binding" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0033613 +name: activating transcription factor binding +namespace: molecular_function +alt_id: GO:0001107 +def: "Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription." [GOC:mah, GOC:txnOH] +synonym: "transcription activator binding" EXACT [] +is_a: GO:0140297 ! DNA-binding transcription factor binding + +[Term] +id: GO:0033614 +name: chloroplast proton-transporting ATP synthase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane." [GOC:mah] +is_a: GO:0043461 ! proton-transporting ATP synthase complex assembly +relationship: part_of GO:0009658 ! chloroplast organization + +[Term] +id: GO:0033615 +name: mitochondrial proton-transporting ATP synthase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane." [GOC:mah] +is_a: GO:0043461 ! proton-transporting ATP synthase complex assembly +intersection_of: GO:0043461 ! proton-transporting ATP synthase complex assembly +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0007005 ! mitochondrion organization + +[Term] +id: GO:0033616 +name: plasma membrane proton-transporting ATP synthase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane." [GOC:mah] +is_a: GO:0043461 ! proton-transporting ATP synthase complex assembly +relationship: part_of GO:0007009 ! plasma membrane organization + +[Term] +id: GO:0033617 +name: mitochondrial cytochrome c oxidase assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane." [GOC:mah] +synonym: "mitochondrial cytochrome c oxidase biogenesis" BROAD [] +synonym: "mitochondrial cytochrome c oxidase complex assembly" EXACT [] +synonym: "mitochondrial respiratory chain complex IV assembly" EXACT [] +is_a: GO:0008535 ! respiratory chain complex IV assembly +is_a: GO:0033108 ! mitochondrial respiratory chain complex assembly +intersection_of: GO:0008535 ! respiratory chain complex IV assembly +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0033618 +name: plasma membrane respiratory chain complex IV assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane." [GOC:mah] +synonym: "plasma membrane cytochrome c oxidase biogenesis" BROAD [] +synonym: "plasma membrane cytochrome c oxidase complex assembly" EXACT [] +is_a: GO:0008535 ! respiratory chain complex IV assembly +relationship: part_of GO:0007009 ! plasma membrane organization + +[Term] +id: GO:0033619 +name: membrane protein proteolysis +namespace: biological_process +def: "The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains." [GOC:pde] +is_a: GO:0006508 ! proteolysis + +[Term] +id: GO:0033620 +name: Mei2 nuclear dot complex +namespace: cellular_component +def: "A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I." [GOC:vw, PMID:12808043] +synonym: "Mei2 dot" EXACT [] +synonym: "Mei2 nuclear dot" BROAD [] +synonym: "nuclear body" RELATED [] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0033621 +name: nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts +namespace: biological_process +def: "The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein." [PMID:16823445] +comment: Note that it is speculated that higher eukaryotic YTH-family protein may be involved in similar mechanisms to supress gene regulation during gametogenesis or general silencing. +synonym: "degradation of meiosis-specific transcripts" EXACT [] +synonym: "mRNA breakdown, meiosis-specific transcripts" EXACT [] +synonym: "mRNA catabolism, meiosis-specific transcripts" EXACT [] +synonym: "mRNA degradation, meiosis-specific transcripts" EXACT [] +synonym: "nuclear mRNA catabolic process, meiosis-specific transcripts" EXACT [] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0033622 +name: integrin activation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands." [GOC:add, PMID:12213832, PMID:14754902] +synonym: "integrin complex activation" EXACT [] +synonym: "integrin complex assembly" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0033623 +name: regulation of integrin activation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of integrin activation." [GOC:add] +synonym: "regulation of integrin complex activation" EXACT [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033622 ! integrin activation +relationship: regulates GO:0033622 ! integrin activation + +[Term] +id: GO:0033624 +name: negative regulation of integrin activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation." [GOC:add] +synonym: "negative regulation of integrin complex activation" EXACT [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0033623 ! regulation of integrin activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033622 ! integrin activation +relationship: negatively_regulates GO:0033622 ! integrin activation + +[Term] +id: GO:0033625 +name: positive regulation of integrin activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of integrin activation." [GOC:add] +synonym: "positive regulation of integrin complex activation" EXACT [] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0033623 ! regulation of integrin activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033622 ! integrin activation +relationship: positively_regulates GO:0033622 ! integrin activation + +[Term] +id: GO:0033626 +name: positive regulation of integrin activation by cell surface receptor linked signal transduction +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands." [GOC:add, PMID:12213832, PMID:14754902] +synonym: "cell surface receptor linked signal transduction leading to integrin activation" EXACT [GOC:bf, GOC:signaling] +synonym: "cell surface receptor linked signal transduction leading to integrin complex activation" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway +is_a: GO:0033625 ! positive regulation of integrin activation +intersection_of: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: positively_regulates GO:0033622 ! integrin activation + +[Term] +id: GO:0033627 +name: cell adhesion mediated by integrin +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits." [GOC:add, PMID:12213832, PMID:14754902] +synonym: "cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0007155 ! cell adhesion + +[Term] +id: GO:0033628 +name: regulation of cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] +synonym: "regulation of cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0030155 ! regulation of cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033627 ! cell adhesion mediated by integrin +relationship: regulates GO:0033627 ! cell adhesion mediated by integrin + +[Term] +id: GO:0033629 +name: negative regulation of cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] +synonym: "negative regulation of cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0007162 ! negative regulation of cell adhesion +is_a: GO:0033628 ! regulation of cell adhesion mediated by integrin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033627 ! cell adhesion mediated by integrin +relationship: negatively_regulates GO:0033627 ! cell adhesion mediated by integrin + +[Term] +id: GO:0033630 +name: positive regulation of cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] +synonym: "positive regulation of cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0033628 ! regulation of cell adhesion mediated by integrin +is_a: GO:0045785 ! positive regulation of cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033627 ! cell adhesion mediated by integrin +relationship: positively_regulates GO:0033627 ! cell adhesion mediated by integrin + +[Term] +id: GO:0033631 +name: cell-cell adhesion mediated by integrin +namespace: biological_process +def: "The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits." [GOC:add, PMID:12213832, PMID:14754902] +synonym: "cell-cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0033627 ! cell adhesion mediated by integrin +is_a: GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0033632 +name: regulation of cell-cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] +synonym: "regulation of cell-cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0033628 ! regulation of cell adhesion mediated by integrin +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033631 ! cell-cell adhesion mediated by integrin +relationship: regulates GO:0033631 ! cell-cell adhesion mediated by integrin + +[Term] +id: GO:0033633 +name: negative regulation of cell-cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] +synonym: "negative regulation of cell-cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0033629 ! negative regulation of cell adhesion mediated by integrin +is_a: GO:0033632 ! regulation of cell-cell adhesion mediated by integrin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033631 ! cell-cell adhesion mediated by integrin +relationship: negatively_regulates GO:0033631 ! cell-cell adhesion mediated by integrin + +[Term] +id: GO:0033634 +name: positive regulation of cell-cell adhesion mediated by integrin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] +synonym: "positive regulation of cell-cell adhesion mediated by integrin complex" EXACT [] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0033630 ! positive regulation of cell adhesion mediated by integrin +is_a: GO:0033632 ! regulation of cell-cell adhesion mediated by integrin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033631 ! cell-cell adhesion mediated by integrin +relationship: positively_regulates GO:0033631 ! cell-cell adhesion mediated by integrin + +[Term] +id: GO:0033635 +name: modulation by symbiont of host response to abiotic stimulus +namespace: biological_process +def: "Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0009628 ! response to abiotic stimulus +relationship: regulates GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0033636 +name: modulation by symbiont of host response to temperature stimulus +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "modulation by symbiont of host response to thermal stimulus" EXACT [] +is_a: GO:0033635 ! modulation by symbiont of host response to abiotic stimulus +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0009266 ! response to temperature stimulus +relationship: regulates GO:0009266 ! response to temperature stimulus + +[Term] +id: GO:0033637 +name: modulation by symbiont of host response to cold +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "freezing tolerance" RELATED [] +is_a: GO:0033636 ! modulation by symbiont of host response to temperature stimulus + +[Term] +id: GO:0033638 +name: modulation by symbiont of host response to heat +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "response to heat shock" RELATED [] +is_a: GO:0033636 ! modulation by symbiont of host response to temperature stimulus + +[Term] +id: GO:0033639 +name: modulation by symbiont of host response to water +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033635 ! modulation by symbiont of host response to abiotic stimulus + +[Term] +id: GO:0033640 +name: modulation by symbiont of host response to osmotic stress +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033635 ! modulation by symbiont of host response to abiotic stimulus +is_a: GO:0047484 ! regulation of response to osmotic stress +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0033641 +name: modulation by symbiont of host response to pH +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033635 ! modulation by symbiont of host response to abiotic stimulus +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0009268 ! response to pH +relationship: regulates GO:0009268 ! response to pH + +[Term] +id: GO:0033642 +name: modulation by symbiont of host response to gravitational stimulus +namespace: biological_process +def: "Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "response to gravitational stimulus" BROAD [] +is_a: GO:0033635 ! modulation by symbiont of host response to abiotic stimulus +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0009629 ! response to gravity +relationship: regulates GO:0009629 ! response to gravity + +[Term] +id: GO:0033643 +name: host cell part +namespace: cellular_component +def: "Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_a: GO:0018995 ! host cellular component +intersection_of: GO:0018995 ! host cellular component +intersection_of: part_of GO:0043657 ! host cell +relationship: part_of GO:0043657 ! host cell + +[Term] +id: GO:0033644 +name: host cell membrane +namespace: cellular_component +def: "Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033643 ! host cell part + +[Term] +id: GO:0033645 +name: host cell endomembrane system +namespace: cellular_component +def: "A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033644 ! host cell membrane + +[Term] +id: GO:0033646 +name: host intracellular part +namespace: cellular_component +def: "Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "host cell intracellular part" EXACT [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0043656 ! host intracellular region + +[Term] +id: GO:0033647 +name: host intracellular organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033646 ! host intracellular part + +[Term] +id: GO:0033648 +name: host intracellular membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "host intracellular membrane-enclosed organelle" EXACT [] +is_a: GO:0033647 ! host intracellular organelle + +[Term] +id: GO:0033650 +name: host cell mitochondrion +namespace: cellular_component +def: "A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "host mitochondria" EXACT [] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part + +[Term] +id: GO:0033651 +name: host cell plastid +namespace: cellular_component +def: "Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0033652 +name: host cell chloroplast +namespace: cellular_component +def: "A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033651 ! host cell plastid + +[Term] +id: GO:0033653 +name: host cell chloroplast part +namespace: cellular_component +def: "Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "host chloroplast component" EXACT [] +is_a: GO:0033652 ! host cell chloroplast + +[Term] +id: GO:0033654 +name: host cell chloroplast thylakoid membrane +namespace: cellular_component +def: "Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033653 ! host cell chloroplast part +is_a: GO:0044160 ! host thylakoid membrane + +[Term] +id: GO:0033655 +name: host cell cytoplasm part +namespace: cellular_component +def: "Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "cytoplasm component" BROAD [] +is_a: GO:0033646 ! host intracellular part +relationship: part_of GO:0030430 ! host cell cytoplasm + +[Term] +id: GO:0033656 +name: modification by symbiont of host chloroplast +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0052043 ! modification by symbiont of host cellular component + +[Term] +id: GO:0033657 +name: modification by symbiont of host chloroplast part +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033656 ! modification by symbiont of host chloroplast + +[Term] +id: GO:0033658 +name: modification by symbiont of host chloroplast thylakoid +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033657 ! modification by symbiont of host chloroplast part + +[Term] +id: GO:0033659 +name: modification by symbiont of host mitochondrion +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0052043 ! modification by symbiont of host cellular component + +[Term] +id: GO:0033660 +name: suppression by symbiont of host resistance gene-dependent defense response +namespace: biological_process +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "down regulation by symbiont of defense response in host by specific elicitors" EXACT [] +synonym: "down-regulation by symbiont of host gene-for-gene resistance" EXACT [] +synonym: "downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "inhibition by symbiont of host resistance gene-dependent defense response" NARROW [] +synonym: "negative regulation by symbiont of host resistance gene-dependent defense response" EXACT [] +synonym: "suppression by symbiont of host resistance gene-dependent defense response" EXACT [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052158 ! modulation by symbiont of host resistance gene-dependent defense response + +[Term] +id: GO:0033661 +name: effector-mediated defense to host-produced reactive oxygen species +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "down regulation by organism of defense-related host metabolic burst" EXACT [] +synonym: "down-regulation by organism of defense-related host oxidative burst" EXACT [] +synonym: "downregulation by organism of defense-related host AOS production" EXACT [] +synonym: "inhibition by organism of defense-related host active oxygen species production" NARROW [] +synonym: "negative regulation by organism of defense-related host reactive oxidative species production" EXACT [] +synonym: "negative regulation by organism of defense-related host reactive oxygen intermediate production" EXACT [] +synonym: "negative regulation by organism of defense-related host respiratory burst" EXACT [] +synonym: "negative regulation by organism of defense-related host ROI production" EXACT [] +synonym: "negative regulation by organism of defense-related host ROS production" EXACT [] +synonym: "negative regulation by symbiont of defense-related host reactive oxygen species production" EXACT [] +synonym: "suppression by symbiont of defense-related host reactive oxygen species production" RELATED [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052164 ! symbiont defense to host-produced reactive oxygen species +is_a: GO:0140415 ! effector-mediated modulation of host defenses by symbiont +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18697 xsd:anyURI + +[Term] +id: GO:0033662 +name: obsolete modulation by symbiont of host defense-related protein level +namespace: biological_process +def: "OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true + +[Term] +id: GO:0033663 +name: obsolete negative regulation by symbiont of host defense-related protein level +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true + +[Term] +id: GO:0033664 +name: obsolete positive regulation by symbiont of host defense-related protein level +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true + +[Term] +id: GO:0033665 +name: obsolete regulation of growth or development of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:dph, GOC:pamgo_curators, GOC:tb] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'regulation of development of symbiont in host ; GO:0044127' and 'regulation of growth of symbiont in host ; GO:0044126'. +synonym: "modulation of growth or development of organism within host" EXACT [] +synonym: "modulation of growth or development of symbiont within host" EXACT [GOC:dph, GOC:tb] +synonym: "modulation of invasive growth" BROAD [] +synonym: "regulation of growth or development of symbiont in host" EXACT [] +synonym: "regulation of growth or development of symbiont within host" EXACT [] +is_obsolete: true +consider: GO:0044127 + +[Term] +id: GO:0033666 +name: obsolete positive regulation of growth or development of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'positive regulation of development of symbiont in host ; GO:0044129' and 'positive regulation of growth of symbiont in host ; GO:0044128'. +synonym: "positive regulation of growth or development of symbiont in host" EXACT [] +synonym: "positive regulation of growth or development of symbiont within host" EXACT [] +synonym: "positive regulation of invasive growth" BROAD [] +synonym: "up regulation of growth or development of organism within host" EXACT [] +synonym: "up-regulation of growth or development of organism within host" EXACT [] +synonym: "upregulation of growth or development of organism within host" EXACT [] +is_obsolete: true +consider: GO:0044129 + +[Term] +id: GO:0033667 +name: obsolete negative regulation of growth or development of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'negative regulation of development of symbiont in host ; GO:0044131' and 'negative regulation of growth of symbiont in host ; GO:0044130'. +synonym: "down regulation of growth or development of organism within host" EXACT [] +synonym: "down-regulation of growth or development of organism within host" EXACT [] +synonym: "downregulation of growth or development of organism within host" EXACT [] +synonym: "inhibition of growth of development of organism within host" NARROW [] +synonym: "negative regulation of growth or development of symbiont in host" EXACT [] +synonym: "negative regulation of growth or development of symbiont within host" EXACT [] +synonym: "negative regulation of invasive growth" BROAD [] +is_obsolete: true +consider: GO:0044131 + +[Term] +id: GO:0033668 +name: negative regulation by symbiont of host apoptotic process +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'. +synonym: "down regulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "down-regulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "downregulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "inhibition by organism of host apoptotic programmed cell death" NARROW [] +synonym: "negative regulation by symbiont of host apoptosis" NARROW [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:0052041 ! negative regulation by symbiont of host programmed cell death +is_a: GO:0052150 ! modulation by symbiont of host apoptotic process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: negatively_regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0033670 +name: regulation of NAD+ kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule." [GOC:mah] +synonym: "NAD kinase regulator" NARROW [] +synonym: "regulation of NAD kinase activity" EXACT [] +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003951 ! NAD+ kinase activity +relationship: regulates GO:0003951 ! NAD+ kinase activity + +[Term] +id: GO:0033671 +name: negative regulation of NAD+ kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule." [GOC:mah] +synonym: "down regulation of NAD+ kinase activity" EXACT [] +synonym: "down-regulation of NAD+ kinase activity" EXACT [] +synonym: "downregulation of NAD+ kinase activity" EXACT [] +synonym: "inhibition of NAD+ kinase activity" NARROW [] +synonym: "NAD+ kinase inhibitor" NARROW [] +is_a: GO:0033670 ! regulation of NAD+ kinase activity +is_a: GO:0033673 ! negative regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003951 ! NAD+ kinase activity +relationship: negatively_regulates GO:0003951 ! NAD+ kinase activity + +[Term] +id: GO:0033672 +name: positive regulation of NAD+ kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule." [GOC:mah] +synonym: "NAD+ kinase activator" NARROW [] +synonym: "stimulation of NAD+ kinase activity" NARROW [] +synonym: "up regulation of NAD+ kinase activity" EXACT [] +synonym: "up-regulation of NAD+ kinase activity" EXACT [] +synonym: "upregulation of NAD+ kinase activity" EXACT [] +is_a: GO:0033670 ! regulation of NAD+ kinase activity +is_a: GO:0033674 ! positive regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003951 ! NAD+ kinase activity +relationship: positively_regulates GO:0003951 ! NAD+ kinase activity + +[Term] +id: GO:0033673 +name: negative regulation of kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] +synonym: "down regulation of kinase activity" EXACT [] +synonym: "down-regulation of kinase activity" EXACT [] +synonym: "downregulation of kinase activity" EXACT [] +synonym: "inhibition of kinase activity" NARROW [] +synonym: "kinase inhibitor" NARROW [] +is_a: GO:0042326 ! negative regulation of phosphorylation +is_a: GO:0043549 ! regulation of kinase activity +is_a: GO:0051348 ! negative regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016301 ! kinase activity +relationship: negatively_regulates GO:0016301 ! kinase activity + +[Term] +id: GO:0033674 +name: positive regulation of kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] +synonym: "kinase activator" NARROW [] +synonym: "stimulation of kinase activity" NARROW [] +synonym: "up regulation of kinase activity" EXACT [] +synonym: "up-regulation of kinase activity" EXACT [] +synonym: "upregulation of kinase activity" EXACT [] +is_a: GO:0042327 ! positive regulation of phosphorylation +is_a: GO:0043549 ! regulation of kinase activity +is_a: GO:0051347 ! positive regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016301 ! kinase activity +relationship: positively_regulates GO:0016301 ! kinase activity + +[Term] +id: GO:0033675 +name: pericanalicular vesicle +namespace: cellular_component +def: "A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes." [PMID:15763347, PMID:9790571] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0033677 +name: DNA/RNA helicase activity +namespace: molecular_function +alt_id: GO:0033680 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA." [GOC:mah] +synonym: "ATP-dependent DNA/RNA helicase activity" EXACT [] +is_a: GO:0004386 ! helicase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0033678 +name: 5'-3' DNA/RNA helicase activity +namespace: molecular_function +alt_id: GO:0033682 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'." [GOC:mah] +synonym: "5' to 3' DNA/RNA helicase activity" EXACT [] +synonym: "ATP-dependent 5' to 3' DNA/RNA helicase activity" EXACT [] +synonym: "ATP-dependent 5'-3' DNA/RNA helicase activity" EXACT [] +is_a: GO:0033677 ! DNA/RNA helicase activity + +[Term] +id: GO:0033679 +name: 3'-5' DNA/RNA helicase activity +namespace: molecular_function +alt_id: GO:0033681 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'." [GOC:mah] +synonym: "3' to 5' DNA/RNA helicase activity" EXACT [] +synonym: "ATP-dependent 3' to 5' DNA/RNA helicase activity" EXACT [] +synonym: "ATP-dependent 3'-5' DNA/RNA helicase activity" EXACT [] +is_a: GO:0033677 ! DNA/RNA helicase activity + +[Term] +id: GO:0033683 +name: nucleotide-excision repair, DNA incision +namespace: biological_process +def: "A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound." [GOC:elh, PMID:8631896] +synonym: "DNA incision involved in nucleotide-excision repair" EXACT [GOC:dph, GOC:tb] +synonym: "nucleic acid cleavage involved in nucleotide-excision repair" EXACT [GOC:dph, GOC:tb] +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +intersection_of: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +intersection_of: part_of GO:0006289 ! nucleotide-excision repair +relationship: part_of GO:0006289 ! nucleotide-excision repair + +[Term] +id: GO:0033684 +name: regulation of luteinizing hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] +is_a: GO:0032276 ! regulation of gonadotropin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032275 ! luteinizing hormone secretion +relationship: regulates GO:0032275 ! luteinizing hormone secretion + +[Term] +id: GO:0033685 +name: negative regulation of luteinizing hormone secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] +synonym: "down regulation of luteinizing hormone secretion" EXACT [] +synonym: "down-regulation of luteinizing hormone secretion" EXACT [] +synonym: "downregulation of luteinizing hormone secretion" EXACT [] +synonym: "inhibition of luteinizing hormone secretion" NARROW [] +is_a: GO:0032277 ! negative regulation of gonadotropin secretion +is_a: GO:0033684 ! regulation of luteinizing hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032275 ! luteinizing hormone secretion +relationship: negatively_regulates GO:0032275 ! luteinizing hormone secretion + +[Term] +id: GO:0033686 +name: positive regulation of luteinizing hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] +synonym: "activation of luteinizing hormone secretion" NARROW [] +synonym: "stimulation of luteinizing hormone secretion" NARROW [] +synonym: "up regulation of luteinizing hormone secretion" EXACT [] +synonym: "up-regulation of luteinizing hormone secretion" EXACT [] +synonym: "upregulation of luteinizing hormone secretion" EXACT [] +is_a: GO:0032278 ! positive regulation of gonadotropin secretion +is_a: GO:0033684 ! regulation of luteinizing hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032275 ! luteinizing hormone secretion +relationship: positively_regulates GO:0032275 ! luteinizing hormone secretion + +[Term] +id: GO:0033687 +name: osteoblast proliferation +namespace: biological_process +def: "The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone." [GOC:mah] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0033688 +name: regulation of osteoblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osteoblast proliferation." [GOC:mah] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033687 ! osteoblast proliferation +relationship: regulates GO:0033687 ! osteoblast proliferation + +[Term] +id: GO:0033689 +name: negative regulation of osteoblast proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation." [GOC:mah] +synonym: "down regulation of osteoblast proliferation" EXACT [] +synonym: "down-regulation of osteoblast proliferation" EXACT [] +synonym: "downregulation of osteoblast proliferation" EXACT [] +synonym: "inhibition of osteoblast proliferation" NARROW [] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0033688 ! regulation of osteoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033687 ! osteoblast proliferation +relationship: negatively_regulates GO:0033687 ! osteoblast proliferation + +[Term] +id: GO:0033690 +name: positive regulation of osteoblast proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of osteoblast proliferation." [GOC:mah] +synonym: "activation of osteoblast proliferation" NARROW [] +synonym: "stimulation of osteoblast proliferation" NARROW [] +synonym: "up regulation of osteoblast proliferation" EXACT [] +synonym: "up-regulation of osteoblast proliferation" EXACT [] +synonym: "upregulation of osteoblast proliferation" EXACT [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0033688 ! regulation of osteoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033687 ! osteoblast proliferation +relationship: positively_regulates GO:0033687 ! osteoblast proliferation + +[Term] +id: GO:0033691 +name: sialic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria." [GOC:add, ISBN:9780721601465] +synonym: "N-acetylneuraminic acid binding" NARROW [] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0033692 +name: cellular polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell." [GOC:go_curators] +synonym: "cellular glycan biosynthesis" EXACT [] +synonym: "cellular glycan biosynthetic process" EXACT [] +synonym: "cellular polysaccharide anabolism" EXACT [] +synonym: "cellular polysaccharide biosynthesis" EXACT [] +synonym: "cellular polysaccharide formation" EXACT [] +synonym: "cellular polysaccharide synthesis" EXACT [] +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0033693 +name: neurofilament bundle assembly +namespace: biological_process +def: "The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules." [PMID:11034913, PMID:11264295] +synonym: "NF bundle assembly" EXACT [] +is_a: GO:0045110 ! intermediate filament bundle assembly + +[Term] +id: GO:0033694 +name: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] +xref: EC:1.5.7 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0033695 +name: oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule." [EC:1.17.5, GOC:mah] +xref: EC:1.17.5 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0033696 +name: negative regulation of extent of heterochromatin assembly +namespace: biological_process +def: "Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin." [GOC:mah] +synonym: "maintenance of heterochromatin boundaries" RELATED [] +synonym: "negative regulation of extent of heterochromatin formation" EXACT [] +synonym: "negative regulation of heterochromatin spreading" RELATED [] +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +is_a: GO:0031454 ! regulation of extent of heterochromatin assembly + +[Term] +id: GO:0033697 +name: positive regulation of extent of heterochromatin assembly +namespace: biological_process +def: "Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin." [GOC:mah] +synonym: "positive regulation of extent of heterochromatin formation" EXACT [] +synonym: "positive regulation of heterochromatin spreading" RELATED [] +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:0031454 ! regulation of extent of heterochromatin assembly + +[Term] +id: GO:0033698 +name: Rpd3L complex +namespace: cellular_component +alt_id: GO:0000508 +def: "A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae)." [GOC:vw, PMID:17450151] +synonym: "Clr6 histone deacetylase complex I/I'" EXACT [GOC:rb, GOC:vw] +synonym: "Clr6L complex" EXACT [PMID:19040720] +synonym: "Rpd3C(L)" EXACT [] +is_a: GO:0070822 ! Sin3-type complex + +[Term] +id: GO:0033699 +name: DNA 5'-adenosine monophosphate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus." [GOC:mah, PMID:16547001, PMID:17276982] +synonym: "AMP-removal activity" RELATED [] +synonym: "DNA 5'-adenylate hydrolase activity" EXACT [] +synonym: "DNA adenylate hydrolysis activity" BROAD [] +synonym: "DNA de-adenylation" RELATED [] +synonym: "DNA deadenylation" RELATED [] +is_a: GO:0035312 ! 5'-3' exodeoxyribonuclease activity + +[Term] +id: GO:0033700 +name: phospholipid efflux +namespace: biological_process +def: "The directed movement of a phospholipid out of a cell or organelle." [GOC:mah] +synonym: "phospholipid export" EXACT [] +is_a: GO:0015914 ! phospholipid transport + +[Term] +id: GO:0033701 +name: dTDP-galactose 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+." [EC:1.1.1.186] +synonym: "dTDP-D-galactose:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.186] +synonym: "dTDPgalactose 6-dehydrogenase activity" EXACT [EC:1.1.1.186] +synonym: "thymidine-diphosphate-galactose dehydrogenase activity" EXACT [EC:1.1.1.186] +xref: EC:1.1.1.186 +xref: MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN +xref: RHEA:12396 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033702 +name: (+)-trans-carveol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH." [EC:1.1.1.275, RHEA:14825] +synonym: "(+)-trans-carveol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.275] +xref: EC:1.1.1.275 +xref: KEGG_REACTION:R06117 +xref: MetaCyc:RXN-9397 +xref: RHEA:14825 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033703 +name: 3beta-hydroxy-5beta-steroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH." [EC:1.1.1.277, RHEA:22944] +synonym: "3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.277] +synonym: "3beta-hydroxysteroid 5beta-oxidoreductase activity" EXACT [EC:1.1.1.277] +synonym: "3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity" EXACT [EC:1.1.1.277] +xref: EC:1.1.1.277 +xref: KEGG_REACTION:R06166 +xref: MetaCyc:1.1.1.277-RXN +xref: RHEA:22944 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033704 +name: 3beta-hydroxy-5alpha-steroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH." [EC:1.1.1.278, RHEA:18137] +synonym: "3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.278] +xref: EC:1.1.1.278 +xref: KEGG_REACTION:R07138 +xref: MetaCyc:1.1.1.278-RXN +xref: RHEA:18137 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033705 +name: GDP-4-dehydro-6-deoxy-D-mannose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+." [EC:1.1.1.281] +comment: Note that this enzyme differs from EC:1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-D-rhamnose (GDP-6-deoxy-D-mannose). +synonym: "GDP-4-keto-6-deoxy-D-mannose reductase activity" BROAD [EC:1.1.1.281] +synonym: "GDP-6-deoxy-D-lyxo-4-hexulose reductase activity" EXACT [EC:1.1.1.281] +synonym: "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity" EXACT [EC:1.1.1.281] +synonym: "Rmd" RELATED [EC:1.1.1.281] +xref: EC:1.1.1.281 +xref: MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033706 +name: obsolete quinate/shikimate dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+." [EC:1.1.1.282] +comment: This term was made obsolete because it represents four reactions, and should be four separate terms. +synonym: "L-quinate:NAD(P)+ 3-oxidoreductase activity" EXACT [EC:1.1.1.282] +synonym: "quinate/shikimate dehydrogenase activity" EXACT [] +synonym: "YdiB" RELATED [EC:1.1.1.282] +is_obsolete: true +consider: GO:0004764 +consider: GO:0030266 +consider: GO:0052733 +consider: GO:0052734 + +[Term] +id: GO:0033707 +name: 3''-deamino-3''-oxonicotianamine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+." [EC:1.1.1.285] +synonym: "2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity" EXACT [EC:1.1.1.285] +xref: EC:1.1.1.285 +xref: MetaCyc:1.1.1.285-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033708 +name: isocitrate-homoisocitrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+." [EC:1.1.1.286] +synonym: "homoisocitrate-isocitrate dehydrogenase activity" EXACT [EC:1.1.1.286] +synonym: "isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.286] +synonym: "PH1722" RELATED [EC:1.1.1.286] +xref: EC:1.1.1.286 +xref: MetaCyc:RXN-7969 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033709 +name: D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+." [EC:1.1.1.287] +synonym: "ARD1p" RELATED [EC:1.1.1.287] +synonym: "D-arabinitol dehydrogenase 1 activity" BROAD [EC:1.1.1.287] +synonym: "D-arabinitol:NADP+ dehydrogenase activity" BROAD [EC:1.1.1.287] +synonym: "NADP+-dependent D-arabinitol dehydrogenase activity" BROAD [EC:1.1.1.287] +xref: KEGG_REACTION:R07144 +xref: MetaCyc:RXN-7972 +xref: RHEA:11868 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033711 +name: 4-phosphoerythronate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH." [EC:1.1.1.290, RHEA:18829] +synonym: "4-O-phosphoerythronate dehydrogenase activity" EXACT [EC:1.1.1.290] +synonym: "4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.290] +synonym: "4PE dehydrogenase activity" EXACT [EC:1.1.1.290] +synonym: "erythronate-4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.290] +synonym: "PdxB" RELATED [EC:1.1.1.290] +synonym: "PdxB 4PE dehydrogenase activity" EXACT [EC:1.1.1.290] +xref: EC:1.1.1.290 +xref: KEGG_REACTION:R04210 +xref: MetaCyc:ERYTHRON4PDEHYDROG-RXN +xref: RHEA:18829 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033712 +name: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH." [EC:1.1.1.292, RHEA:24208] +synonym: "1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.292] +synonym: "AFR" RELATED [EC:1.1.1.292] +xref: EC:1.1.1.292 +xref: KEGG_REACTION:R08194 +xref: MetaCyc:1.1.1.292-RXN +xref: RHEA:24208 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033713 +name: choline:oxygen 1-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide." [EC:1.1.3.17, RHEA:13505] +synonym: "choline oxidase activity" BROAD [EC:1.1.3.17] +xref: EC:1.1.3.17 +xref: MetaCyc:CHOLINE-OXIDASE-RXN +xref: RHEA:13505 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0033714 +name: secondary-alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone." [EC:1.1.3.18, RHEA:23180] +synonym: "polyvinyl alcohol oxidase activity" EXACT [EC:1.1.3.18] +synonym: "secondary alcohol oxidase activity" EXACT [EC:1.1.3.18] +synonym: "secondary-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.18] +xref: EC:1.1.3.18 +xref: KEGG_REACTION:R02277 +xref: MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN +xref: RHEA:23180 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0033715 +name: nucleoside oxidase activity +namespace: molecular_function +def: "Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O." [EC:1.1.3.28, RHEA:28651] +synonym: "nucleoside:oxygen 5'-oxidoreductase activity" EXACT [EC:1.1.3.28] +xref: EC:1.1.3.28 +xref: MetaCyc:NUCLEOSIDE-OXIDASE-RXN +xref: RHEA:28651 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0033716 +name: nucleoside oxidase (hydrogen peroxide-forming) activity +namespace: molecular_function +def: "Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide." [EC:1.1.3.39, RHEA:15489] +comment: Two other reactions might be associated with this activity: (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide. +synonym: "nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity" EXACT [EC:1.1.3.39] +xref: EC:1.1.3.39 +xref: MetaCyc:1.1.3.39-RXN +xref: RHEA:15489 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0033717 +name: gluconate 2-dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor." [EC:1.1.99.3] +synonym: "2-ketogluconate reductase activity" BROAD [EC:1.1.99.3] +synonym: "D-gluconate dehydrogenase activity" EXACT [EC:1.1.99.3] +synonym: "D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity" EXACT [EC:1.1.99.3] +synonym: "D-gluconate:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.3] +synonym: "D-gluconate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.3] +synonym: "gluconate oxidase activity" EXACT [EC:1.1.99.3] +synonym: "gluconic acid dehydrogenase activity" EXACT [EC:1.1.99.3] +synonym: "gluconic dehydrogenase activity" EXACT [EC:1.1.99.3] +xref: EC:1.1.99.3 +xref: MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN +xref: RHEA:12769 +is_a: GO:0008875 ! gluconate dehydrogenase activity + +[Term] +id: GO:0033718 +name: pyranose dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor." [EC:1.1.99.29] +synonym: "PDH" RELATED [EC:1.1.99.29] +synonym: "pyranose dehydrogenase activity" EXACT [EC:1.1.99.29] +synonym: "pyranose-quinone oxidoreductase activity" EXACT [EC:1.1.99.29] +synonym: "pyranose:acceptor oxidoreductase activity" EXACT [EC:1.1.99.29] +synonym: "quinone-dependent pyranose dehydrogenase activity" EXACT [EC:1.1.99.29] +xref: EC:1.1.99.29 +xref: MetaCyc:RXN-7961 +xref: MetaCyc:RXN-7962 +xref: MetaCyc:RXN-7963 +xref: MetaCyc:RXN-7965 +xref: MetaCyc:RXN-7966 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0033719 +name: 2-oxo-acid reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor." [EC:1.1.99.30] +synonym: "(2R)-hydroxy-carboxylate:acceptor oxidoreductase activity" EXACT [EC:1.1.99.30] +synonym: "(2R)-hydroxycarboxylate-viologen-oxidoreductase activity" EXACT [EC:1.1.99.30] +synonym: "2-oxoacid reductase activity" EXACT [EC:1.1.99.30] +synonym: "HVOR" RELATED [EC:1.1.99.30] +xref: EC:1.1.99.30 +xref: MetaCyc:1.1.99.30-RXN +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0033720 +name: (S)-mandelate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor." [EC:1.1.99.31] +synonym: "(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.31] +synonym: "L(+)-mandelate dehydrogenase activity" EXACT [EC:1.1.99.31] +synonym: "MDH" RELATED [EC:1.1.99.31] +xref: EC:1.1.99.31 +xref: MetaCyc:MANDELATE-DEHYDROGENASE-RXN +xref: MetaCyc:MANDELATE-OXY-RXN +xref: RHEA:15749 +xref: UM-BBD_reactionID:r1048 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0033721 +name: aldehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+." [EC:1.2.1.4] +synonym: "aldehyde:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.4] +synonym: "NADP-acetaldehyde dehydrogenase activity" EXACT [EC:1.2.1.4] +synonym: "NADP-dependent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.4] +xref: EC:1.2.1.4 +xref: MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:11888 +is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0033722 +name: malonate-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+." [EC:1.2.1.15] +synonym: "3-oxopropanoate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.15] +synonym: "malonic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.15] +xref: EC:1.2.1.15 +xref: MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033723 +name: fluoroacetaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+." [EC:1.2.1.69] +synonym: "fluoroacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.69] +xref: EC:1.2.1.69 +xref: RHEA:16677 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0033726 +name: aldehyde ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin." [EC:1.2.7.5] +synonym: "aldehyde:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.5] +synonym: "AOR" RELATED [EC:1.2.7.5] +synonym: "tungsten-containing aldehyde ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.5] +xref: EC:1.2.7.5 +xref: MetaCyc:1.2.7.5-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0033727 +name: aldehyde dehydrogenase (FAD-independent) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor." [EC:1.2.99.7] +synonym: "aldehyde oxidoreductase activity" EXACT [EC:1.2.99.7] +synonym: "aldehyde:acceptor oxidoreductase (FAD-independent) activity" EXACT [EC:1.2.99.7] +synonym: "AORDd" RELATED [EC:1.2.99.7] +synonym: "Mop" RELATED [EC:1.2.99.7] +xref: EC:1.2.99.7 +xref: MetaCyc:1.2.99.3-RXN +xref: MetaCyc:1.2.99.7-RXN +xref: MetaCyc:CARBOXYLATE-REDUCTASE-RXN +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0033728 +name: divinyl chlorophyllide a 8-vinyl-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+." [EC:1.3.1.75] +synonym: "4VCR" RELATED [EC:1.3.1.75] +synonym: "[4-vinyl]chlorophyllide a reductase activity" EXACT [EC:1.3.1.75] +synonym: "chlorophyllide-a:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.75] +xref: EC:1.3.1.75 +xref: MetaCyc:RXN-5286 +xref: RHEA:14449 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033729 +name: anthocyanidin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+." [EC:1.3.1.77] +synonym: "ANR" RELATED [EC:1.3.1.77] +synonym: "AtANR" RELATED [EC:1.3.1.77] +synonym: "flavan-3-ol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.77] +synonym: "MtANR" RELATED [EC:1.3.1.77] +xref: EC:1.3.1.77 +xref: MetaCyc:1.3.1.77-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033730 +name: arogenate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2." [EC:1.3.1.78] +synonym: "arogenic dehydrogenase activity" BROAD [EC:1.3.1.78] +synonym: "L-arogenate:NADP+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.3.1.78] +synonym: "pretyrosine dehydrogenase activity" BROAD [EC:1.3.1.78] +synonym: "TyrAa" RELATED [EC:1.3.1.78] +synonym: "TyrAAT1" RELATED [EC:1.3.1.78] +synonym: "TyrAAT2" RELATED [EC:1.3.1.78] +xref: EC:1.3.1.78 +xref: MetaCyc:1.3.1.78-RXN +xref: RHEA:15417 +is_a: GO:0033731 ! arogenate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0033731 +name: arogenate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2." [EC:1.3.1.79] +synonym: "arogenic dehydrogenase activity" BROAD [EC:1.3.1.79] +synonym: "L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.3.1.79] +synonym: "pretyrosine dehydrogenase activity" BROAD [EC:1.3.1.79] +xref: EC:1.3.1.79 +xref: MetaCyc:1.3.1.79-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033732 +name: pyrroloquinoline-quinone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone." [EC:1.3.3.11, RHEA:10692] +synonym: "6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity" EXACT [EC:1.3.3.11] +synonym: "PqqC" RELATED [EC:1.3.3.11] +xref: EC:1.3.3.11 +xref: KEGG_REACTION:R07353 +xref: MetaCyc:1.3.3.11-RXN +xref: RHEA:10692 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0033734 +name: (R)-benzylsuccinyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein." [EC:1.3.8.3] +synonym: "(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.8.3] +synonym: "(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.8.3] +synonym: "BbsG" RELATED [EC:1.3.8.3] +xref: EC:1.3.8.3 +xref: RHEA:20876 +xref: UM-BBD_reactionID:r0330 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0033735 +name: aspartate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+." [EC:1.4.1.21] +synonym: "L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity" EXACT [EC:1.4.1.21] +synonym: "NAD-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] +synonym: "NADH2-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] +synonym: "NADP+-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] +xref: EC:1.4.1.21 +xref: KEGG_REACTION:R07164 +xref: KEGG_REACTION:R07165 +xref: MetaCyc:1.4.1.21-RXN +xref: RHEA:11784 +xref: RHEA:11788 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0033736 +name: L-lysine 6-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+)." [EC:1.4.3.20, RHEA:22548] +synonym: "L-lysine-epsilon-oxidase activity" EXACT [EC:1.4.3.20] +synonym: "L-lysine:oxygen 6-oxidoreductase (deaminating) activity" EXACT [EC:1.4.3.20] +synonym: "Lod" RELATED [EC:1.4.3.20] +synonym: "LodA" RELATED [EC:1.4.3.20] +synonym: "marinocine" RELATED [EC:1.4.3.20] +xref: EC:1.4.3.20 +xref: KEGG_REACTION:R07598 +xref: MetaCyc:1.4.3.20-RXN +xref: RHEA:22548 +is_a: GO:0001716 ! L-amino-acid oxidase activity + +[Term] +id: GO:0033737 +name: 1-pyrroline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+." [MetaCyc:1.5.1.35-RXN] +synonym: "1-pyrroline:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.35] +synonym: "ABALDH" RELATED [EC:1.5.1.35] +synonym: "gamma-aminobutyraldehyde dehydrogenase activity" EXACT [EC:1.5.1.35] +synonym: "YdcW" RELATED [EC:1.5.1.35] +xref: EC:1.2.1.19 +xref: MetaCyc:1.5.1.35-RXN +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0033738 +name: methylenetetrahydrofolate reductase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin." [EC:1.5.7.1] +synonym: "5,10-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.7.1] +synonym: "5-methyltetrahydrofolate:ferredoxin oxidoreductase activity" EXACT [EC:1.5.7.1] +xref: EC:1.5.7.1 +xref: MetaCyc:RXN-5061 +is_a: GO:0033694 ! oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0033739 +name: preQ1 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH." [EC:1.7.1.13, RHEA:13409] +synonym: "7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity" EXACT systematic_synonym [EC:1.7.1.13] +synonym: "7-cyano-7-deazaguanine reductase activity" EXACT [EC:1.7.1.13] +synonym: "preQ0 oxidoreductase activity" EXACT [EC:1.7.1.13] +synonym: "preQ0 reductase activity" EXACT [EC:1.7.1.13] +synonym: "QueF" RELATED [EC:1.7.1.13] +synonym: "queuine synthase activity" RELATED [] +synonym: "queuine:NADP+ oxidoreductase activity" RELATED [] +synonym: "YkvM" RELATED [EC:1.7.1.13] +xref: EC:1.7.1.13 +xref: KEGG_REACTION:R07605 +xref: MetaCyc:RXN0-4022 +xref: RHEA:13409 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0033740 +name: hydroxylamine oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor." [EC:1.7.2.8] +synonym: "hydroxylamine:acceptor oxidoreductase activity" EXACT [EC:1.7.2.8] +xref: EC:1.7.2.8 +xref: MetaCyc:1.7.99.8-RXN +xref: RHEA:23232 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033741 +name: adenylyl-sulfate reductase (glutathione) activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione." [EC:1.8.4.9, RHEA:14141] +synonym: "5'-adenylylsulfate reductase activity" EXACT [EC:1.8.4.9] +synonym: "AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity" EXACT [EC:1.8.4.9] +synonym: "AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity" EXACT [EC:1.8.4.9] +synonym: "plant-type 5'-adenylylsulfate reductase activity" NARROW [EC:1.8.4.9] +xref: EC:1.8.4.9 +xref: KEGG_REACTION:R05717 +xref: MetaCyc:1.8.4.9-RXN +xref: RHEA:14141 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0033743 +name: peptide-methionine (R)-S-oxide reductase activity +namespace: molecular_function +alt_id: GO:0000318 +def: "Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.8.4.12, GOC:mah, GOC:vw, RHEA:24164] +synonym: "methionine S-oxide reductase (R-form oxidizing) activity" EXACT [EC:1.8.4.12] +synonym: "methionine S-oxide reductase activity" BROAD [EC:1.8.4.12] +synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.12] +synonym: "methionine sulfoxide reductase B activity" NARROW [EC:1.8.4.12] +synonym: "MsrB" RELATED [EC:1.8.4.12] +synonym: "peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity" EXACT [EC:1.8.4.12] +synonym: "PilB" RELATED [EC:1.8.4.12] +synonym: "pMRsr" RELATED [EC:1.8.4.12] +synonym: "pMSR" RELATED [EC:1.8.4.12] +synonym: "protein-methionine-R-oxide reductase activity" EXACT [] +synonym: "selenoprotein R" RELATED [EC:1.8.4.12] +synonym: "SelR" RELATED [EC:1.8.4.12] +synonym: "SelX" RELATED [EC:1.8.4.12] +xref: EC:1.8.4.12 +xref: KEGG_REACTION:R07607 +xref: MetaCyc:1.8.4.12-RXN +xref: Reactome:R-HSA-5676917 "MRSBs reduce L-methyl-(R)-S-oxide to L-methionine" +xref: RHEA:24164 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0033744 +name: L-methionine:thioredoxin-disulfide S-oxidoreductase activity +namespace: molecular_function +alt_id: GO:0000317 +def: "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin." [EC:1.8.4.13] +synonym: "acetylmethionine sulfoxide reductase activity" EXACT [EC:1.8.4.13] +synonym: "free-methionine (S)-S-oxide reductase activity" EXACT [EC:1.8.4.13] +synonym: "fSMsr" RELATED [EC:1.8.4.13] +synonym: "L-methionine-(S)-S-oxide reductase activity" NARROW [GOC:bf, GOC:vw] +synonym: "L-methionine:oxidized-thioredoxin S-oxidoreductase activity" EXACT [EC:1.8.4.13] +synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.13] +synonym: "methionine-S-oxide reductase activity" EXACT [PMID:11169920] +synonym: "methyl sulfoxide reductase I and II activity" EXACT [EC:1.8.4.13] +xref: EC:1.8.4.13 +xref: KEGG_REACTION:R07606 +xref: MetaCyc:1.8.4.13-RXN +xref: RHEA:19993 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0033745 +name: L-methionine-(R)-S-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin." [EC:1.8.4.14] +synonym: "free met-R-(o) reductase activity" EXACT [EC:1.8.4.14] +synonym: "free-methionine (R)-S-oxide reductase activity" EXACT [EC:1.8.4.14] +synonym: "FRMsr" RELATED [EC:1.8.4.14] +synonym: "L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity" EXACT [EC:1.8.4.14] +xref: EC:1.8.4.14 +xref: MetaCyc:1.8.4.14-RXN +xref: RHEA:21260 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0033746 +name: histone demethylase activity (H3-R2 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein." [GOC:mah] +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0070078 ! histone H3-R2 demethylation + +[Term] +id: GO:0033747 +name: obsolete versatile peroxidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O." [EC:1.11.1.16] +synonym: "hybrid peroxidase activity" EXACT [EC:1.11.1.16] +synonym: "polyvalent peroxidase activity" EXACT [EC:1.11.1.16] +synonym: "reactive-black-5:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.16] +synonym: "versatile peroxidase activity" EXACT [] +synonym: "VP" RELATED [EC:1.11.1.16] +is_obsolete: true +replaced_by: GO:0004601 +consider: GO:0052750 + +[Term] +id: GO:0033748 +name: hydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: H2 + A = AH2." [EC:1.12.99.6] +synonym: "H2 producing hydrogenase activity" BROAD [EC:1.12.99.6] +synonym: "hydrogen-lyase activity" BROAD [EC:1.12.99.6] +synonym: "hydrogen:(acceptor) oxidoreductase activity" EXACT [EC:1.12.99.6] +synonym: "hydrogen:acceptor oxidoreductase activity" EXACT [EC:1.12.99.6] +synonym: "hydrogenlyase activity" BROAD [EC:1.12.99.6] +synonym: "uptake hydrogenase activity" BROAD [EC:1.12.99.6] +xref: EC:1.12.99.6 +xref: MetaCyc:RXN0-4141 +xref: MetaCyc:RXN0-5256 +xref: RHEA:12116 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0033749 +name: histone demethylase activity (H4-R3 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein." [GOC:mah] +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0070079 ! histone H4-R3 demethylation + +[Term] +id: GO:0033750 +name: ribosome localization +namespace: biological_process +alt_id: GO:0033753 +def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah] +synonym: "establishment of ribosome localisation" RELATED [] +synonym: "establishment of ribosome localization" RELATED [] +synonym: "ribosome localisation" RELATED [] +is_a: GO:0008104 ! protein localization +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0033751 +name: linoleate 8R-lipoxygenase +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate." [RHEA:22392] +synonym: "5,8-linoleate diol synthase (bifunctional enzyme)" RELATED [EC:1.13.11.60] +synonym: "7,8-linoleate diol synthase (bifunctional enzyme)" RELATED [EC:1.13.11.60] +synonym: "linoleate diol synthase activity" RELATED [] +xref: RHEA:22392 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0033752 +name: acetylacetone-cleaving enzyme activity +namespace: molecular_function +def: "Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal." [EC:1.13.11.50] +synonym: "acetylacetone dioxygenase activity" EXACT [EC:1.13.11.50] +synonym: "acetylacetone-cleaving enzyme" RELATED [EC:1.13.11.50] +synonym: "acetylacetone:oxygen oxidoreductase activity" EXACT [EC:1.13.11.50] +synonym: "diketone cleaving dioxygenase activity" EXACT [EC:1.13.11.50] +synonym: "diketone cleaving enzyme" RELATED [EC:1.13.11.50] +synonym: "Dke1" RELATED [EC:1.13.11.50] +xref: EC:1.13.11.50 +xref: RHEA:12877 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0033754 +name: indoleamine 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine." [EC:1.13.11.52] +synonym: "D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity" NARROW [EC:1.13.11.52] +synonym: "IDO" RELATED [EC:1.13.11.52] +synonym: "tryptophan pyrrolase activity" BROAD [EC:1.13.11.52] +xref: EC:1.13.11.52 +xref: MetaCyc:RXN-8664 +xref: MetaCyc:RXN-8665 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0033755 +name: sulfur oxygenase/reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+." [EC:1.13.11.55] +synonym: "SOR" RELATED [EC:1.13.11.55] +synonym: "sulfur oxygenase activity" BROAD [EC:1.13.11.55] +synonym: "sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity" EXACT [EC:1.13.11.55] +synonym: "sulphur oxygenase/reductase activity" EXACT [] +xref: EC:1.13.11.55 +xref: MetaCyc:1.13.11.55-RXN +xref: RHEA:13957 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0033756 +name: Oplophorus-luciferin 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu." [EC:1.13.12.13] +synonym: "Oplophorus luciferase activity" EXACT [EC:1.13.12.13] +synonym: "Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity" EXACT [EC:1.13.12.13] +xref: EC:1.13.12.13 +xref: MetaCyc:RXN-3361 +xref: RHEA:20417 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0033757 +name: glucoside 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor." [EC:1.1.99.13] +synonym: "D-aldohexopyranoside dehydrogenase" EXACT [EC:1.1.99.13] +synonym: "D-aldohexoside:(acceptor) 3-oxidoreductase" EXACT [EC:1.1.99.13] +synonym: "D-aldohexoside:acceptor 3-oxidoreductase" EXACT [EC:1.1.99.13] +synonym: "D-aldohexoside:cytochrome c oxidoreductase" EXACT [EC:1.1.99.13] +synonym: "hexopyranoside-cytochrome c oxidoreductase" EXACT [EC:1.1.99.13] +xref: EC:1.1.99.13 +xref: MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN +xref: RHEA:16589 +xref: Wikipedia:Glucoside_3-dehydrogenase +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0033758 +name: clavaminate synthase activity +namespace: molecular_function +def: "Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O." [EC:1.14.11.21] +synonym: "clavaminate synthase 2 activity" NARROW [EC:1.14.11.21] +synonym: "clavaminic acid synthase activity" EXACT [EC:1.14.11.21] +synonym: "deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.21] +xref: EC:1.14.11.21 +xref: MetaCyc:1.14.11.21-RXN +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0033759 +name: flavone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O." [EC:1.14.20.5] +synonym: "flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity" EXACT [EC:1.14.20.5] +synonym: "flavone synthase I activity" EXACT [EC:1.14.20.5] +synonym: "FNS I" RELATED [EC:1.14.20.5] +xref: EC:1.14.20.5 +xref: MetaCyc:RXN-8000 +xref: RHEA:10448 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +relationship: part_of GO:0051553 ! flavone biosynthetic process + +[Term] +id: GO:0033760 +name: 2'-deoxymugineic-acid 2'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate." [EC:1.14.11.24, RHEA:12200] +synonym: "2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity" EXACT [EC:1.14.11.24] +synonym: "IDS3" RELATED [EC:1.14.11.24] +xref: EC:1.14.11.24 +xref: KEGG_REACTION:R07185 +xref: MetaCyc:1.14.11.24-RXN +xref: RHEA:12200 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0033761 +name: mugineic-acid 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2." [EC:1.14.11.25] +synonym: "IDS2" RELATED [EC:1.14.11.25] +synonym: "mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.25] +xref: EC:1.14.11.25 +xref: KEGG_REACTION:R07186 +xref: MetaCyc:RXN-7982 +xref: RHEA:14509 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0033762 +name: response to glucagon +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] +synonym: "response to glucagon stimulus" EXACT [GOC:dos] +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0033763 +name: proline 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.28] +synonym: "L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.28] +synonym: "P-3-H" RELATED [EC:1.14.11.28] +xref: EC:1.14.11.28 +xref: MetaCyc:1.14.11.28-RXN +xref: RHEA:20265 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0033764 +name: steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative." [GOC:mah] +is_a: GO:0016229 ! steroid dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033765 +name: steroid dehydrogenase activity, acting on the CH-CH group of donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative." [GOC:mah] +is_a: GO:0016229 ! steroid dehydrogenase activity +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0033766 +name: 2-hydroxyquinoline 8-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol." [EC:1.14.13.61, RHEA:22080] +synonym: "2-oxo-1,2-dihydroquinoline 8-monooxygenase activity" EXACT [EC:1.14.13.61] +synonym: "quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity" EXACT [EC:1.14.13.61] +xref: EC:1.14.13.61 +xref: KEGG_REACTION:R05158 +xref: MetaCyc:1.14.13.61-RXN +xref: RHEA:22080 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033767 +name: 4-hydroxyacetophenone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+)." [EC:1.14.13.84, RHEA:22916] +synonym: "(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity" EXACT systematic_synonym [EC:1.14.13.84] +synonym: "HAPMO" RELATED [EC:1.14.13.84] +xref: EC:1.14.13.84 +xref: KEGG_REACTION:R06892 +xref: MetaCyc:1.14.13.84-RXN +xref: RHEA:22916 +xref: UM-BBD_reactionID:r0756 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033768 +name: SUMO-targeted ubiquitin ligase complex +namespace: cellular_component +def: "A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes." [GOC:vw, PMID:17762864, PMID:17762865] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex + +[Term] +id: GO:0033769 +name: glyceollin synthase activity +namespace: molecular_function +def: "Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O." [EC:1.14.13.85] +synonym: "2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity" EXACT [EC:1.14.13.85] +synonym: "dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity" EXACT [EC:1.14.13.85] +xref: EC:1.14.13.85 +xref: MetaCyc:2.5.1.36-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033770 +name: 2-hydroxyisoflavanone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O." [EC:1.14.13.86] +synonym: "2-HIS" RELATED [EC:1.14.13.86] +synonym: "apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity" EXACT [EC:1.14.13.86] +xref: EC:1.14.13.86 +xref: MetaCyc:RXN-7750 +xref: RHEA:14897 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033771 +name: licodione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+)." [EC:1.14.14.140, RHEA:15697] +synonym: "(2S)-flavanone 2-hydroxylase activity" EXACT [EC:1.14.14.140] +synonym: "liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity" EXACT [EC:1.14.14.140] +xref: EC:1.14.14.140 +xref: KEGG_REACTION:R07198 +xref: MetaCyc:1.14.13.87-RXN +xref: RHEA:15697 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033772 +name: flavonoid 3',5'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O." [EC:1.14.14.81] +synonym: "F3',5'H" RELATED [EC:1.14.14.81] +synonym: "F3'5'H" RELATED [EC:1.14.14.81] +synonym: "flavanone,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.14.81] +xref: EC:1.14.14.81 +xref: MetaCyc:RXN-7783 +xref: MetaCyc:RXN-8671 +xref: RHEA:55448 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033773 +name: isoflavone 2'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: an isoflavone + NADPH + H+ + O2 = a 2'-hydroxyisoflavone + NADP+ + H2O." [EC:1.14.13.89] +synonym: "CYP Ge-3" RELATED [EC:1.14.13.89] +synonym: "CYP81E1" RELATED [EC:1.14.13.89] +synonym: "isoflavone 2'-monooxygenase activity" BROAD [EC:1.14.13.89] +synonym: "isoflavone,NADPH:oxygen oxidoreductase (2'-hydroxylating) activity" EXACT [EC:1.14.13.89] +xref: EC:1.14.13.89 +xref: MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033774 +name: basal labyrinth +namespace: cellular_component +def: "A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane." [GOC:mah, GOC:sart, PMID:11640882] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045178 ! basal part of cell + +[Term] +id: GO:0033775 +name: deoxysarpagine hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine." [EC:1.14.14.136, RHEA:14237] +synonym: "10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity" EXACT [EC:1.14.14.136] +synonym: "DOSH" RELATED [EC:1.14.14.136] +xref: EC:1.14.14.136 +xref: KEGG_REACTION:R05828 +xref: MetaCyc:1.14.13.91-RXN +xref: RHEA:14237 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033776 +name: phenylacetone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+)." [EC:1.14.13.92, RHEA:10124] +synonym: "PAMO" RELATED [EC:1.14.13.92] +synonym: "phenylacetone,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.92] +xref: EC:1.14.13.92 +xref: KEGG_REACTION:R07201 +xref: MetaCyc:1.14.13.92-RXN +xref: RHEA:10124 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033777 +name: lithocholate 6beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+)." [EC:1.14.14.138, RHEA:18857] +synonym: "6beta-hydroxylase activity" BROAD [EC:1.14.14.138] +synonym: "CYP3A10" RELATED [EC:1.14.14.138] +synonym: "cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity" EXACT [EC:1.14.14.138] +synonym: "lithocholate 6beta-monooxygenase activity" EXACT [EC:1.14.14.138] +synonym: "lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity" EXACT [EC:1.14.14.138] +xref: EC:1.14.14.138 +xref: KEGG_REACTION:R07203 +xref: MetaCyc:1.14.13.94-RXN +xref: RHEA:18857 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033778 +name: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+)." [EC:1.14.13.95, RHEA:10504] +synonym: "7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity" EXACT [EC:1.14.13.95] +synonym: "7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity" EXACT [EC:1.14.13.95] +synonym: "CYP12" RELATED [EC:1.14.13.95] +synonym: "HCO 12alpha-hydroxylase activity" EXACT [EC:1.14.13.95] +synonym: "sterol 12alpha-hydroxylase activity" BROAD [EC:1.14.13.95] +xref: EC:1.14.13.95 +xref: KEGG_REACTION:R04826 +xref: MetaCyc:1.14.13.95-RXN +xref: Reactome:R-HSA-192157 "CYP8B1 12-hydroxylates 4CHOL7aOLONE" +xref: Reactome:R-HSA-193709 "CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL" +xref: Reactome:R-HSA-193845 "CYP8B1 12-hydroxylates 4CHOL7a,27DONE" +xref: RHEA:10504 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033779 +name: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+)." [EC:1.14.14.139, RHEA:15261] +synonym: "5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity" EXACT [EC:1.14.14.139] +synonym: "5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity" EXACT [EC:1.14.14.139] +synonym: "CYP8B1" RELATED [EC:1.14.14.139] +synonym: "cytochrome P450 8B1" RELATED [EC:1.14.14.139] +synonym: "sterol 12alpha-hydroxylase activity" BROAD [EC:1.14.14.139] +xref: EC:1.14.14.139 +xref: KEGG_REACTION:R07204 +xref: MetaCyc:1.14.13.96-RXN +xref: RHEA:15261 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033780 +name: taurochenodeoxycholate 6alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O." [EC:1.14.13.97] +synonym: "CYP3A4" RELATED [EC:1.14.13.97] +synonym: "CYP4A21" RELATED [EC:1.14.13.97] +synonym: "taurochenodeoxycholate 6alpha-monooxygenase activity" EXACT [EC:1.14.13.97] +synonym: "taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity" EXACT [EC:1.14.13.97] +xref: EC:1.14.13.97 +xref: MetaCyc:RXN-7977 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033781 +name: cholesterol 24-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+)." [EC:1.14.14.25, RHEA:22716] +synonym: "cholesterol 24-monooxygenase activity" EXACT [EC:1.14.14.25] +synonym: "cholesterol 24S-hydroxylase activity" EXACT [EC:1.14.14.25] +synonym: "cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity" EXACT [EC:1.14.14.25] +synonym: "CYP46" RELATED [EC:1.14.14.25] +synonym: "CYP46A1" RELATED [EC:1.14.14.25] +synonym: "cytochrome P450 46A1" RELATED [EC:1.14.14.25] +xref: EC:1.14.14.25 +xref: KEGG_REACTION:R07207 +xref: MetaCyc:1.14.13.98-RXN +xref: Reactome:R-HSA-192061 "CYP46A1 24-hydroxylates CHOL" +xref: RHEA:22716 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033782 +name: 24-hydroxycholesterol 7alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+)." [EC:1.14.13.99, RHEA:16093] +synonym: "(24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" EXACT [EC:1.14.13.99] +synonym: "24-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.99] +synonym: "CYP39A1" RELATED [EC:1.14.13.99] +synonym: "CYP39A1 oxysterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.99] +xref: EC:1.14.13.99 +xref: KEGG_REACTION:R07208 +xref: MetaCyc:1.14.13.99-RXN +xref: RHEA:16093 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033783 +name: 25-hydroxycholesterol 7alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O." [EC:1.14.14.29] +synonym: "25-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.14.29] +synonym: "cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" EXACT [EC:1.14.14.29] +synonym: "CYP7B1" RELATED [EC:1.14.14.29] +synonym: "CYP7B1 oxysterol 7alpha-hydroxylase activity" EXACT [EC:1.14.14.29] +xref: EC:1.14.14.29 +xref: MetaCyc:RXN-7980 +xref: MetaCyc:RXN-7981 +xref: RHEA:19041 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033784 +name: senecionine N-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide." [EC:1.14.13.101, RHEA:11420] +synonym: "senecionine monooxygenase (N-oxide-forming) activity" EXACT [EC:1.14.13.101] +synonym: "senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity" EXACT [EC:1.14.13.101] +synonym: "SNO" RELATED [EC:1.14.13.101] +xref: EC:1.14.13.101 +xref: KEGG_REACTION:R07373 +xref: MetaCyc:1.14.13.101-RXN +xref: RHEA:11420 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0033785 +name: heptose 7-phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP." [MetaCyc:RXN0-4341] +synonym: "D-alpha,beta-D-heptose 7-phosphate 1-kinase activity" EXACT [] +xref: EC:2.7.1 +xref: MetaCyc:RXN0-4341 +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0033786 +name: heptose-1-phosphate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose." [MetaCyc:RXN0-4342] +synonym: "D-beta-D-heptose 1-phosphate adenylyltransferase activity" EXACT [] +synonym: "heptose 1-phosphate adenyltransferase activity" EXACT [] +xref: MetaCyc:RXN0-4342 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0033787 +name: cyanocobalamin reductase (cyanide-eliminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH." [EC:1.16.1.6, RHEA:16113] +synonym: "cob(I)alamin, cyanide:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.6] +synonym: "cyanocobalamin reductase (NADPH, cyanide-eliminating) activity" EXACT [EC:1.16.1.6] +synonym: "cyanocobalamin reductase (NADPH; CN-eliminating) activity" EXACT [EC:1.16.1.6] +synonym: "cyanocobalamin reductase activity" EXACT [EC:1.16.1.6] +synonym: "NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity" EXACT [EC:1.16.1.6] +synonym: "NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity" EXACT [EC:1.16.1.6] +xref: EC:1.16.1.6 +xref: KEGG_REACTION:R02999 +xref: MetaCyc:1.6.99.12-RXN +xref: Reactome:R-HSA-3149519 "MMACHC decyanates CNCbl" +xref: RHEA:16113 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0033788 +name: leucoanthocyanidin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+." [EC:1.17.1.3] +synonym: "(2R,3S)-catechin:NADP+ 4-oxidoreductase activity" EXACT [EC:1.17.1.3] +synonym: "leucocyanidin reductase activity" EXACT [EC:1.17.1.3] +xref: EC:1.17.1.3 +xref: MetaCyc:RXN-1484 +xref: RHEA:10616 +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0033789 +name: phenylacetyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA." [EC:1.17.5.1, RHEA:15705] +synonym: "phenylacetyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.17.5.1] +synonym: "phenylacetyl-CoA:quinone oxidoreductase activity" EXACT [EC:1.17.5.1] +xref: EC:1.17.5.1 +xref: KEGG_REACTION:R07222 +xref: MetaCyc:1.17.5.1-RXN +xref: RHEA:15705 +is_a: GO:0033695 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor + +[Term] +id: GO:0033790 +name: hydroxymethylfurfural reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033791 +name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor." [EC:1.17.99.3] +synonym: "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity" EXACT [EC:1.17.99.3] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity" EXACT [EC:1.17.99.3] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity" EXACT [EC:1.17.99.3] +synonym: "THC-CoA oxidase activity" EXACT [EC:1.17.99.3] +synonym: "THCA-CoA oxidase activity" EXACT [EC:1.17.99.3] +synonym: "trihydroxycoprostanoyl-CoA oxidase activity" EXACT [EC:1.17.99.3] +xref: EC:1.17.99.3 +xref: MetaCyc:1.17.99.3-RXN +xref: RHEA:15733 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0033792 +name: bile-acid 7alpha-dehydroxylase activity +namespace: molecular_function +def: "Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2." [EC:1.17.99.5] +synonym: "7alpha-dehydroxylase activity" EXACT [EC:1.17.99.5] +synonym: "bile acid 7-dehydroxylase activity" EXACT [EC:1.17.99.5] +synonym: "cholate 7alpha-dehydroxylase activity" EXACT [EC:1.17.99.5] +synonym: "deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity" EXACT [EC:1.17.99.5] +synonym: "deoxycholate:NAD+ oxidoreductase activity" EXACT [EC:1.17.99.5] +xref: EC:1.17.99.5 +xref: MetaCyc:RXN-8658 +xref: MetaCyc:RXN-8659 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0033793 +name: aureusidin synthase activity +namespace: molecular_function +def: "Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O." [EC:1.21.3.6] +synonym: "2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity" EXACT [EC:1.21.3.6] +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0033794 +name: sarcosine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin." [EC:1.21.4.3] +synonym: "acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity" EXACT [EC:1.21.4.3] +xref: EC:1.21.4.3 +xref: RHEA:12825 +is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor + +[Term] +id: GO:0033795 +name: betaine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin." [EC:1.21.4.4] +synonym: "acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity" EXACT [EC:1.21.4.4] +xref: EC:1.21.4.4 +xref: RHEA:11848 +is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor + +[Term] +id: GO:0033796 +name: sulfur reductase activity +namespace: molecular_function +def: "Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide." [EC:1.12.98.4] +synonym: "(donor):sulfur oxidoreductase activity" EXACT [EC:1.12.98.4] +synonym: "sulphur reductase activity" EXACT [] +xref: EC:1.12.98.4 +xref: MetaCyc:1.97.1.3-RXN +xref: MetaCyc:RXN-8269 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0033797 +name: selenate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite." [EC:1.97.1.9, RHEA:14031] +synonym: "selenite:reduced acceptor oxidoreductase activity" EXACT [EC:1.97.1.9] +xref: EC:1.97.1.9 +xref: KEGG_REACTION:R07229 +xref: MetaCyc:RXN0-2101 +xref: RHEA:14031 +xref: UM-BBD_reactionID:r0828 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0033798 +name: thyroxine 5-deiodinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2." [EC:1.21.99.3] +synonym: "acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity" EXACT [EC:1.21.99.3] +synonym: "diiodothyronine 5'-deiodinase activity" BROAD [EC:1.21.99.3] +synonym: "inner ring-deiodinating pathway" EXACT [PMID:20403357] +synonym: "iodothyronine 5-deiodinase activity" EXACT [EC:1.21.99.3] +synonym: "iodothyronine inner ring monodeiodinase activity" EXACT [EC:1.21.99.3] +synonym: "type III iodothyronine deiodinase activity" NARROW [EC:1.21.99.3] +xref: EC:1.21.99.3 +xref: MetaCyc:1.97.1.11-RXN +xref: RHEA:18897 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0033799 +name: myricetin 3'-O-methyltransferase activity +namespace: molecular_function +alt_id: GO:0102437 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin." [MetaCyc:RXN-8451, RHEA:25629] +comment: Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267 +synonym: "CrCOMT2" RELATED [] +synonym: "flavonoid 3',5'-O-dimethyltransferase activity" RELATED [] +synonym: "myricetin 3-O-methyltransferase activity" RELATED [] +synonym: "S-adenosyl-L-methionine:myricetin O-methyltransferase activity" RELATED [] +xref: EC:2.1.1.267; +xref: KEGG_REACTION:R06815 +xref: MetaCyc:RXN-13912 +xref: MetaCyc:RXN-8451 +xref: RHEA:25629 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0033800 +name: isoflavone 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone." [EC:2.1.1.150] +synonym: "S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.150] +xref: EC:2.1.1.150 +xref: MetaCyc:RXN-6241 +xref: RHEA:17933 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0033801 +name: vitexin 2''-O-rhamnoside 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside." [EC:2.1.1.153] +synonym: "S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity" EXACT [EC:2.1.1.153] +xref: EC:2.1.1.153 +xref: MetaCyc:RXN-4981 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0033802 +name: isoliquiritigenin 2'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.154, RHEA:21608] +synonym: "chalcone OMT" RELATED [EC:2.1.1.154] +synonym: "CHMT" RELATED [EC:2.1.1.154] +synonym: "S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity" EXACT [EC:2.1.1.154] +xref: EC:2.1.1.154 +xref: KEGG_REACTION:R07242 +xref: MetaCyc:RXN-3501 +xref: RHEA:21608 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0033803 +name: kaempferol 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide." [EC:2.1.1.155, RHEA:15105] +synonym: "F 4'-OMT" RELATED [EC:2.1.1.155] +synonym: "S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity" EXACT [EC:2.1.1.155] +synonym: "S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity" EXACT [EC:2.1.1.155] +xref: EC:2.1.1.155 +xref: KEGG_REACTION:R06807 +xref: MetaCyc:2.1.1.155-RXN +xref: RHEA:15105 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0033804 +name: obsolete glycine/sarcosine N-methyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine." [EC:2.1.1.156] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "ApGSMT" RELATED [EC:2.1.1.156] +synonym: "glycine sarcosine N-methyltransferase activity" EXACT [EC:2.1.1.156] +synonym: "glycine-sarcosine methyltransferase activity" EXACT [EC:2.1.1.156] +synonym: "glycine/sarcosine N-methyltransferase activity" EXACT [] +synonym: "GMT" RELATED [EC:2.1.1.156] +synonym: "GSMT" RELATED [EC:2.1.1.156] +synonym: "S-adenosyl-L-methionine:sarcosine N-methyltransferase activity" EXACT [EC:2.1.1.156] +is_obsolete: true +consider: GO:0017174 +consider: GO:0052730 + +[Term] +id: GO:0033805 +name: obsolete sarcosine/dimethylglycine N-methyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine." [EC:2.1.1.157] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "ApDMT" RELATED [EC:2.1.1.157] +synonym: "S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity" NARROW [EC:2.1.1.157] +synonym: "sarcosine dimethylglycine methyltransferase activity" NARROW [EC:2.1.1.157] +synonym: "sarcosine dimethylglycine N-methyltransferase activity" NARROW [EC:2.1.1.157] +synonym: "sarcosine/dimethylglycine N-methyltransferase activity" EXACT [] +synonym: "SDMT" RELATED [EC:2.1.1.157] +is_obsolete: true +consider: GO:0052729 +consider: GO:0052730 + +[Term] +id: GO:0033806 +name: fluorothreonine transaldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine." [EC:2.2.1.8] +synonym: "fluoroacetaldehyde:L-threonine aldehydetransferase activity" EXACT [EC:2.2.1.8] +xref: EC:2.2.1.8 +xref: RHEA:11748 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0033807 +name: icosanoyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+." [EC:2.3.1.119] +synonym: "acyl-CoA elongase activity" EXACT [EC:2.3.1.119] +synonym: "C18-CoA elongase activity" EXACT [EC:2.3.1.119] +synonym: "stearoyl-CoA elongase activity" EXACT [EC:2.3.1.119] +synonym: "stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity" EXACT [EC:2.3.1.119] +xref: EC:2.3.1.119 +xref: MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033808 +name: 6'-deoxychalcone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O." [EC:2.3.1.170] +synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity" EXACT [EC:2.3.1.170] +xref: EC:2.3.1.170 +xref: MetaCyc:RXN-3142 +xref: RHEA:10584 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033809 +name: anthocyanin 6''-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside)." [EC:2.3.1.171] +synonym: "3MaT" RELATED [EC:2.3.1.171] +synonym: "Dv3MaT" RELATED [EC:2.3.1.171] +synonym: "malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.171] +synonym: "malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.171] +xref: EC:2.3.1.171 +xref: MetaCyc:2.3.1.171-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033810 +name: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin." [EC:2.3.1.172] +synonym: "malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity" EXACT [EC:2.3.1.172] +synonym: "Ss5MaT1" RELATED [EC:2.3.1.172] +xref: EC:2.3.1.172 +xref: MetaCyc:2.3.1.172-RXN +xref: RHEA:21988 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033811 +name: flavonol-3-O-triglucoside O-coumaroyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]." [EC:2.3.1.173] +synonym: "4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity" EXACT [EC:2.3.1.173] +xref: EC:2.3.1.173 +xref: MetaCyc:2.3.1.173-RXN +xref: RHEA:22160 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033812 +name: 3-oxoadipyl-CoA thiolase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA." [EC:2.3.1.174] +synonym: "succinyl-CoA:acetyl-CoA C-succinyltransferase activity" EXACT [EC:2.3.1.174] +xref: EC:2.3.1.174 +xref: MetaCyc:RXN-3641 +xref: RHEA:19481 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033813 +name: deacetylcephalosporin-C acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA." [EC:2.3.1.175, RHEA:23860] +synonym: "acetyl coenzyme A:DAC acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "acetyl-CoA:DAC acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "acetyl-CoA:DAC O-acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "cefG" RELATED [EC:2.3.1.175] +synonym: "CPC acetylhydrolase activity" EXACT [EC:2.3.1.175] +synonym: "DAC acetyltransferase activity" EXACT [EC:2.3.1.175] +synonym: "DAC-AT" RELATED [EC:2.3.1.175] +synonym: "deacetylcephalosporin C acetyltransferase activity" EXACT [EC:2.3.1.175] +xref: EC:2.3.1.175 +xref: KEGG_REACTION:R03064 +xref: MetaCyc:2.3.1.175-RXN +xref: RHEA:23860 +is_a: GO:0016408 ! C-acyltransferase activity + +[Term] +id: GO:0033814 +name: propanoyl-CoA C-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA." [EC:2.3.1.176] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity" EXACT [EC:2.3.1.176] +synonym: "peroxisomal thiolase 2 activity" NARROW [EC:2.3.1.176] +synonym: "PTE-2" RELATED [EC:2.3.1.176] +synonym: "SCP-X" RELATED [EC:2.3.1.176] +synonym: "SCPchi" RELATED [EC:2.3.1.176] +synonym: "sterol carrier protein-chi" RELATED [EC:2.3.1.176] +synonym: "sterol carrier protein-X" RELATED [EC:2.3.1.176] +xref: EC:2.3.1.176 +xref: MetaCyc:2.3.1.176-RXN +xref: RHEA:16865 +is_a: GO:0016408 ! C-acyltransferase activity + +[Term] +id: GO:0033815 +name: biphenyl synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2." [EC:2.3.1.177] +synonym: "BIS" RELATED [EC:2.3.1.177] +synonym: "malonyl-CoA:benzoyl-CoA malonyltransferase activity" EXACT [EC:2.3.1.177] +xref: EC:2.3.1.177 +xref: MetaCyc:2.3.1.177-RXN +xref: RHEA:22292 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033816 +name: diaminobutyrate acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+)." [EC:2.3.1.178, RHEA:16901] +synonym: "2,4-diaminobutanoate acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "DAB acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "DABA acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "DABAcT" RELATED [EC:2.3.1.178] +synonym: "diaminobutyric acid acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "EctA" RELATED [EC:2.3.1.178] +synonym: "L-2,4-diaminobutanoate acetyltransferase activity" EXACT [EC:2.3.1.178] +synonym: "L-2,4-diaminobutyrate acetyltransferase activity" EXACT [EC:2.3.1.178] +xref: EC:2.3.1.178 +xref: KEGG_REACTION:R06978 +xref: MetaCyc:R102-RXN +xref: RHEA:16901 +is_a: GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0033817 +name: beta-ketoacyl-acyl-carrier-protein synthase II activity +namespace: molecular_function +def: "Catalysis of the reaction: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]." [EC:2.3.1.179] +synonym: "(Z)-hexadec-11-enoyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating) activity" EXACT [EC:2.3.1.179] +synonym: "3-oxoacyl-acyl carrier protein synthase I activity" EXACT [EC:2.3.1.179] +synonym: "beta-ketoacyl-ACP synthase II activity" EXACT [EC:2.3.1.179] +synonym: "FabF" RELATED [EC:2.3.1.179] +synonym: "KAS II" RELATED [EC:2.3.1.179] +synonym: "KASII" RELATED [EC:2.3.1.179] +xref: EC:2.3.1.179 +xref: MetaCyc:2.3.1.179-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033818 +name: beta-ketoacyl-acyl-carrier-protein synthase III activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2." [EC:2.3.1.180] +synonym: "3-ketoacyl-acyl carrier protein synthase III activity" EXACT [EC:2.3.1.180] +synonym: "3-oxoacyl:ACP synthase III activity" EXACT [EC:2.3.1.180] +synonym: "acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity" EXACT [EC:2.3.1.180] +synonym: "beta-ketoacyl (acyl carrier protein) synthase III activity" EXACT [EC:2.3.1.180] +synonym: "beta-ketoacyl-ACP synthase III activity" EXACT [EC:2.3.1.180] +synonym: "beta-ketoacyl-acyl carrier protein synthase III activity" EXACT [EC:2.3.1.180] +synonym: "FabH" RELATED [EC:2.3.1.180] +synonym: "KAS III" RELATED [EC:2.3.1.180] +synonym: "KASIII" RELATED [EC:2.3.1.180] +xref: EC:2.3.1.180 +xref: MetaCyc:2.3.1.180-RXN +xref: RHEA:12080 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033819 +name: lipoyl(octanoyl) transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein." [EC:2.3.1.181] +synonym: "LipB" RELATED [EC:2.3.1.181] +synonym: "lipoate/octanoate transferase activity" EXACT [EC:2.3.1.181] +synonym: "lipoyl (octanoyl)-acyl carrier protein:protein transferase activity" EXACT [EC:2.3.1.181] +synonym: "lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity" EXACT [EC:2.3.1.181] +synonym: "octanoyl-acyl carrier protein-protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] +synonym: "octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] +synonym: "octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] +xref: EC:2.3.1.181 +xref: MetaCyc:RXN0-947 +xref: Reactome:R-HSA-6793590 "LIPT2 transfers octanoyl group to GCSH" +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0033820 +name: DNA alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA." [EC:2.4.1.26] +synonym: "T2-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] +synonym: "T4-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] +synonym: "T6-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] +synonym: "UDP-glucose:DNA alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.26] +synonym: "UDPglucose-DNA alpha-glucosyltransferase activity" EXACT [EC:2.4.1.26] +synonym: "uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity" EXACT [EC:2.4.1.26] +xref: EC:2.4.1.26 +xref: MetaCyc:2.4.1.26-RXN +is_a: GO:0046527 ! glucosyltransferase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0033821 +name: DNA beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA." [EC:2.4.1.27] +synonym: "T4 phage beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] +synonym: "T4-beta-glucosyl transferase activity" EXACT [EC:2.4.1.27] +synonym: "T4-HMC-beta-glucosyl transferase activity" EXACT [EC:2.4.1.27] +synonym: "UDP glucose-DNA beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] +synonym: "UDP-glucose:DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.27] +synonym: "UDPglucose:DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.27] +synonym: "uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] +xref: EC:2.4.1.27 +xref: MetaCyc:2.4.1.27-RXN +is_a: GO:0046527 ! glucosyltransferase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0033822 +name: glucosyl-DNA beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA." [EC:2.4.1.28] +synonym: "T6-beta-glucosyl transferase activity" EXACT [EC:2.4.1.28] +synonym: "T6-glucosyl-HMC-beta-glucosyl transferase activity" EXACT [EC:2.4.1.28] +synonym: "UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.28] +synonym: "UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.28] +synonym: "uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity" EXACT [EC:2.4.1.28] +xref: EC:2.4.1.28 +xref: MetaCyc:2.4.1.28-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033823 +name: procollagen glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen." [EC:2.4.1.66] +synonym: "collagen glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "collagen hydroxylysyl glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "galactosylhydroxylysine glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "galactosylhydroxylysine-glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "galactosylhydroxylysyl glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "UDP-glucose-collagenglucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity" EXACT [EC:2.4.1.66] +synonym: "uridine diphosphoglucose-collagen glucosyltransferase activity" EXACT [EC:2.4.1.66] +xref: EC:2.4.1.66 +xref: MetaCyc:PROCOLLAGEN-GLUCOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-1981157 "Glucosylation of collagen propeptide hydroxylysines" +is_a: GO:0046527 ! glucosyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0033824 +name: alternansucrase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages." [EC:2.4.1.140] +synonym: "sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.140] +synonym: "sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.140] +synonym: "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity" BROAD [EC:2.4.1.140] +xref: EC:2.4.1.140 +xref: MetaCyc:2.4.1.140-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033825 +name: oligosaccharide 4-alpha-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides." [EC:2.4.1.161] +synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.161] +synonym: "1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.161] +synonym: "amylase III activity" EXACT [EC:2.4.1.161] +xref: EC:2.4.1.161 +xref: MetaCyc:2.4.1.161-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033826 +name: xyloglucan 4-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage." [EC:2.4.1.168] +synonym: "UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] +synonym: "UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] +synonym: "uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity" EXACT [EC:2.4.1.168] +synonym: "xyloglucan 4beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] +synonym: "xyloglucan glucosyltransferase activity" EXACT [EC:2.4.1.168] +xref: EC:2.4.1.168 +xref: MetaCyc:2.4.1.168-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033827 +name: high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum." [EC:2.4.1.197] +synonym: "acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] +synonym: "UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] +synonym: "UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] +synonym: "uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] +xref: EC:2.4.1.197 +xref: MetaCyc:2.4.1.197-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0033828 +name: glucosylglycerol-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+)." [EC:2.4.1.213, RHEA:12881] +synonym: "ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.213] +synonym: "ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.213] +synonym: "GG-phosphate synthase activity" EXACT [EC:2.4.1.213] +synonym: "GGPS" RELATED [EC:2.4.1.213] +synonym: "glucosyl-glycerol-phosphate synthase activity" EXACT [EC:2.4.1.213] +xref: EC:2.4.1.213 +xref: KEGG_REACTION:R05328 +xref: MetaCyc:2.4.1.213-RXN +xref: RHEA:12881 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033829 +name: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor." [EC:2.4.1.222] +synonym: "O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.222] +synonym: "UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.222] +xref: EC:2.4.1.222 +xref: MetaCyc:2.4.1.222-RXN +xref: Reactome:R-HSA-1912355 "Glycosylation of Pre-NOTCH by FRINGE" +xref: Reactome:R-HSA-5096538 "Defective LFNG does not transfer GlcNAc to Pre-NOTCH" +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0033830 +name: Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline." [EC:2.4.1.229] +synonym: "Skp1-HyPro GlcNAc-transferase activity" EXACT [EC:2.4.1.229] +synonym: "UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity" EXACT [EC:2.4.1.229] +synonym: "UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity" EXACT [EC:2.4.1.229] +synonym: "UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity" EXACT [EC:2.4.1.229] +synonym: "UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity" EXACT [EC:2.4.1.229] +xref: EC:2.4.1.229 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0033831 +name: kojibiose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose." [EC:2.4.1.230, RHEA:11176] +synonym: "2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.230] +xref: EC:2.4.1.230 +xref: KEGG_REACTION:R07264 +xref: MetaCyc:2.4.1.230-RXN +xref: RHEA:11176 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033832 +name: alpha,alpha-trehalose phosphorylase (configuration-retaining) activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate." [EC:2.4.1.231] +synonym: "alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.231] +synonym: "trehalose phosphorylase activity" BROAD [EC:2.4.1.231] +xref: MetaCyc:RXN-4441 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033833 +name: hydroxymethylfurfural reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] +xref: MetaCyc:RXN-10738 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033834 +name: kaempferol 3-O-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside." [EC:2.4.1.234] +synonym: "F3GalTase activity" EXACT [EC:2.4.1.234] +synonym: "UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.234] +xref: EC:2.4.1.234 +xref: MetaCyc:2.4.1.234-RXN +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0033835 +name: flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]." [EC:2.4.1.236] +synonym: "1->2 UDP-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] +synonym: "UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] +synonym: "UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] +xref: EC:2.4.1.236 +xref: MetaCyc:RXN-5001 +xref: MetaCyc:RXN-5002 +xref: MetaCyc:RXN-5004 +xref: MetaCyc:RXN-7759 +xref: MetaCyc:RXN-9699 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0033836 +name: flavonol 7-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside." [EC:2.4.1.237] +synonym: "UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.237] +synonym: "UDP-glucose:flavonol 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.237] +xref: EC:2.4.1.237 +xref: MetaCyc:2.4.1.237-RXN +xref: RHEA:23164 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033837 +name: anthocyanin 3'-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside." [EC:2.4.1.238] +synonym: "3'GT" RELATED [EC:2.4.1.238] +synonym: "UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.238] +synonym: "UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity" EXACT [EC:2.4.1.238] +xref: EC:2.4.1.238 +xref: MetaCyc:2.4.1.238-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033838 +name: flavonol-3-O-glucoside glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside." [EC:2.4.1.239] +synonym: "UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.239] +xref: EC:2.4.1.239 +xref: MetaCyc:2.4.1.239-RXN +xref: RHEA:18893 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033839 +name: flavonol-3-O-glycoside glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside." [EC:2.4.1.240] +synonym: "UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.240] +xref: EC:2.4.1.240 +xref: MetaCyc:2.4.1.240-RXN +xref: RHEA:23544 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033840 +name: NDP-glucose-starch glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1." [EC:2.4.1.242] +synonym: "GBSS" RELATED [EC:2.4.1.242] +synonym: "GBSSI" RELATED [EC:2.4.1.242] +synonym: "GBSSII" RELATED [EC:2.4.1.242] +synonym: "granule-bound starch synthase activity" EXACT [EC:2.4.1.242] +synonym: "granule-bound starch synthase I activity" EXACT [EC:2.4.1.242] +synonym: "granule-bound starch synthase II activity" EXACT [EC:2.4.1.242] +synonym: "NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.242] +synonym: "NDPglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.242] +synonym: "starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.242] +synonym: "starch synthase II activity" EXACT [EC:2.4.1.242] +synonym: "waxy protein" RELATED [EC:2.4.1.242] +xref: EC:2.4.1.242 +xref: MetaCyc:2.4.1.242-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0033841 +name: 6G-fructosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0)." [EC:2.4.1.243] +synonym: "1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity" EXACT [EC:2.4.1.243] +synonym: "6G-FFT" RELATED [EC:2.4.1.243] +synonym: "6G-fructotransferase activity" EXACT [EC:2.4.1.243] +synonym: "6G-FT" RELATED [EC:2.4.1.243] +synonym: "fructan:fructan 6G-fructosyltransferase activity" EXACT [EC:2.4.1.243] +xref: EC:2.4.1.243 +xref: MetaCyc:2.4.1.243-RXN +is_a: GO:0050738 ! fructosyltransferase activity + +[Term] +id: GO:0033842 +name: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group." [EC:2.4.1.244] +synonym: "beta1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.244] +synonym: "beta1,4-N-acetylgalactosaminyltransferase III activity" EXACT [EC:2.4.1.244] +synonym: "beta1,4-N-acetylgalactosaminyltransferase IV activity" EXACT [EC:2.4.1.244] +synonym: "beta4GalNAc-T3" RELATED [EC:2.4.1.244] +synonym: "beta4GalNAc-T4" RELATED [EC:2.4.1.244] +synonym: "UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.244] +xref: EC:2.4.1.244 +xref: MetaCyc:2.4.1.244-RXN +xref: RHEA:20493 +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0033843 +name: xyloglucan 6-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage." [EC:2.4.2.39] +synonym: "UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity" EXACT [EC:2.4.2.39] +synonym: "uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity" EXACT [EC:2.4.2.39] +synonym: "xyloglucan 6-alpha-D-xylosyltransferase activity" EXACT [EC:2.4.2.39] +xref: EC:2.4.2.39 +xref: MetaCyc:2.4.2.39-RXN +is_a: GO:0042285 ! xylosyltransferase activity + +[Term] +id: GO:0033844 +name: galactose-6-sulfurylase activity +namespace: molecular_function +def: "Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues." [EC:2.5.1.5] +synonym: "D-galactose-6-sulfate:alkyltransferase (cyclizing) activity" EXACT [EC:2.5.1.5] +synonym: "galactose 6-sulfatase activity" EXACT [EC:2.5.1.5] +synonym: "galactose-6-sulfatase activity" EXACT [EC:2.5.1.5] +synonym: "porphyran sulfatase activity" EXACT [EC:2.5.1.5] +xref: EC:2.5.1.5 +xref: MetaCyc:2.5.1.5-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033845 +name: hydroxymethylfurfural reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0033846 +name: adenosyl-fluoride synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine." [EC:2.5.1.63] +synonym: "fluorinase activity" EXACT [EC:2.5.1.63] +synonym: "S-adenosyl-L-methionine:fluoride adenosyltransferase activity" EXACT [EC:2.5.1.63] +xref: EC:2.5.1.63 +xref: MetaCyc:2.5.1.63-RXN +xref: RHEA:16661 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033847 +name: O-phosphoserine sulfhydrylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate." [EC:2.5.1.65] +synonym: "O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.65] +synonym: "O-phosphoserine(thiol)-lyase activity" EXACT [EC:2.5.1.65] +xref: EC:2.5.1.65 +xref: MetaCyc:2.5.1.65-RXN +xref: RHEA:10252 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033848 +name: N2-(2-carboxyethyl)arginine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate." [EC:2.5.1.66, RHEA:10556] +synonym: "CEA synthetase activity" EXACT [EC:2.5.1.66] +synonym: "CEAS" RELATED [EC:2.5.1.66] +synonym: "glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity" EXACT [EC:2.5.1.66] +synonym: "glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity" EXACT [EC:2.5.1.66] +synonym: "N2-(2-carboxyethyl)arginine synthetase activity" EXACT [EC:2.5.1.66] +xref: EC:2.5.1.66 +xref: KEGG_REACTION:R05465 +xref: MetaCyc:2.5.1.66-RXN +xref: RHEA:10556 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033849 +name: chrysanthemyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate." [EC:2.5.1.67, RHEA:14009] +synonym: "CPPase activity" EXACT [EC:2.5.1.67] +synonym: "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity" EXACT [EC:2.5.1.67] +xref: EC:2.5.1.67 +xref: KEGG_REACTION:R08948 +xref: MetaCyc:2.5.1.67-RXN +xref: RHEA:14009 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033850 +name: Z-farnesyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate." [EC:2.5.1.68, RHEA:23300] +synonym: "(Z)-farnesyl diphosphate synthase activity" EXACT [EC:2.5.1.68] +synonym: "geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity" EXACT [EC:2.5.1.68] +xref: EC:2.5.1.68 +xref: KEGG_REACTION:R08528 +xref: MetaCyc:2.5.1.68-RXN +xref: RHEA:23300 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033851 +name: lavandulyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate." [EC:2.5.1.69, RHEA:21676] +synonym: "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity" EXACT [EC:2.5.1.69] +synonym: "FDS-5" RELATED [EC:2.5.1.69] +xref: EC:2.5.1.69 +xref: KEGG_REACTION:R08950 +xref: MetaCyc:2.5.1.69-RXN +xref: RHEA:21676 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0033852 +name: thyroid-hormone transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate." [EC:2.6.1.26, RHEA:19133] +synonym: "3,5-dinitrotyrosine aminotransferase activity" EXACT [EC:2.6.1.26] +synonym: "3,5-dinitrotyrosine transaminase activity" EXACT [EC:2.6.1.26] +synonym: "L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.26] +synonym: "thyroid hormone aminotransferase activity" EXACT [EC:2.6.1.26] +synonym: "thyroid-hormone aminotransferase activity" EXACT [EC:2.6.1.26] +xref: EC:2.6.1.26 +xref: KEGG_REACTION:R03952 +xref: MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN +xref: RHEA:19133 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0033853 +name: aspartate-prephenate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate." [EC:2.6.1.78] +synonym: "L-arogenate:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.78] +synonym: "L-aspartate:prephenate aminotransferase activity" EXACT [EC:2.6.1.78] +synonym: "PAT" RELATED [EC:2.6.1.78] +synonym: "prephenate aspartate aminotransferase activity" EXACT [EC:2.6.1.78] +synonym: "prephenate transaminase activity" BROAD [EC:2.6.1.78] +xref: EC:2.6.1.78 +xref: MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN +xref: RHEA:20445 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0033854 +name: glutamate-prephenate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate." [EC:2.6.1.79, RHEA:22880] +synonym: "L-arogenate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.79] +synonym: "L-glutamate:prephenate aminotransferase activity" EXACT [EC:2.6.1.79] +synonym: "PAT" RELATED [EC:2.6.1.79] +synonym: "prephenate transaminase activity" BROAD [EC:2.6.1.79] +xref: EC:2.6.1.79 +xref: KEGG_REACTION:R07276 +xref: MetaCyc:PREPHENATE-TRANSAMINE-RXN +xref: RHEA:22880 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0033855 +name: nicotianamine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate." [EC:2.6.1.80, RHEA:22104] +synonym: "NAAT" RELATED [EC:2.6.1.80] +synonym: "NAAT-I" RELATED [EC:2.6.1.80] +synonym: "NAAT-II" RELATED [EC:2.6.1.80] +synonym: "NAAT-III" RELATED [EC:2.6.1.80] +synonym: "nicotianamine transaminase activity" EXACT [EC:2.6.1.80] +synonym: "nicotianamine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.80] +xref: EC:2.6.1.80 +xref: KEGG_REACTION:R07277 +xref: MetaCyc:2.6.1.80-RXN +xref: RHEA:22104 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0033856 +name: pyridoxine 5'-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate." [EC:2.6.99.2, RHEA:15265] +synonym: "1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity" EXACT [EC:2.6.99.2] +synonym: "PdxJ" RELATED [EC:2.6.99.2] +synonym: "PNP synthase activity" EXACT [EC:2.6.99.2] +synonym: "pyridoxine 5-phosphate phospho lyase activity" EXACT [EC:2.6.99.2] +xref: EC:2.6.99.2 +xref: KEGG_REACTION:R05838 +xref: MetaCyc:PDXJ-RXN +xref: RHEA:15265 +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups + +[Term] +id: GO:0033857 +name: diphosphoinositol-pentakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate." [EC:2.7.4.24] +synonym: "ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity" EXACT [EC:2.7.4.24] +synonym: "PP-InsP5 kinase activity" EXACT [EC:2.7.4.24] +synonym: "PP-IP5 kinase activity" EXACT [EC:2.7.4.24] +synonym: "PPIP5K" RELATED [EC:2.7.4.24] +synonym: "PPIP5K1" RELATED [EC:2.7.4.24] +synonym: "PPIP5K2" RELATED [EC:2.7.4.24] +synonym: "VIP1" NARROW [EC:2.7.4.24] +synonym: "VIP2" NARROW [EC:2.7.4.24] +xref: EC:2.7.4.24 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0033858 +name: N-acetylgalactosamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate." [EC:2.7.1.157] +synonym: "ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity" EXACT [EC:2.7.1.157] +synonym: "GALK2" RELATED [EC:2.7.1.157] +synonym: "GalNAc kinase activity" EXACT [EC:2.7.1.157] +synonym: "GK2" RELATED [EC:2.7.1.157] +synonym: "N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity" EXACT [EC:2.7.1.157] +xref: EC:2.7.1.157 +xref: MetaCyc:2.7.1.157-RXN +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0033859 +name: furaldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass." [GOC:jp, PMID:15338422, PMID:16652391] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0033860 +name: regulation of NAD(P)H oxidase activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme NAD(P)H oxidase." [GOC:mah] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity +relationship: regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity + +[Term] +id: GO:0033861 +name: negative regulation of NAD(P)H oxidase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase." [GOC:mah] +synonym: "down regulation of NAD(P)H oxidase activity" EXACT [] +synonym: "down-regulation of NAD(P)H oxidase activity" EXACT [] +synonym: "downregulation of NAD(P)H oxidase activity" EXACT [] +synonym: "inhibition of NAD(P)H oxidase activity" NARROW [] +is_a: GO:0033860 ! regulation of NAD(P)H oxidase activity +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity +relationship: negatively_regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity + +[Term] +id: GO:0033862 +name: UMP kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + UMP = ADP + UDP." [EC:2.7.4.22] +synonym: "ATP:UMP phosphotransferase activity" EXACT [EC:2.7.4.22] +synonym: "PyrH" RELATED [EC:2.7.4.22] +synonym: "SmbA" RELATED [EC:2.7.4.22] +synonym: "UMP-kinase activity" EXACT [EC:2.7.4.22] +synonym: "UMPK" RELATED [EC:2.7.4.22] +synonym: "uridine monophosphate kinase activity" EXACT [EC:2.7.4.22] +xref: EC:2.7.4.22 +xref: MetaCyc:2.7.4.22-RXN +xref: RHEA:24400 +is_a: GO:0009041 ! uridylate kinase activity + +[Term] +id: GO:0033863 +name: ribose 1,5-bisphosphate phosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+)." [EC:2.7.4.23, RHEA:20109] +synonym: "ATP:ribose-1,5-bisphosphate phosphotransferase activity" EXACT [EC:2.7.4.23] +synonym: "PhnN" RELATED [EC:2.7.4.23] +synonym: "ribose 1,5-bisphosphokinase activity" EXACT [EC:2.7.4.23] +xref: EC:2.7.4.23 +xref: KEGG_REACTION:R06836 +xref: MetaCyc:2.7.4.23-RXN +xref: RHEA:20109 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0033864 +name: positive regulation of NAD(P)H oxidase activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme NAD(P)H oxidase." [GOC:mah] +synonym: "activation of NAD(P)H oxidase activity" NARROW [] +synonym: "stimulation of NAD(P)H oxidase activity" NARROW [] +synonym: "up regulation of NAD(P)H oxidase activity" EXACT [] +synonym: "up-regulation of NAD(P)H oxidase activity" EXACT [] +synonym: "upregulation of NAD(P)H oxidase activity" EXACT [] +is_a: GO:0033860 ! regulation of NAD(P)H oxidase activity +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity +relationship: positively_regulates GO:0016174 ! NAD(P)H oxidase (H(2)O(2)-forming activity + +[Term] +id: GO:0033865 +name: nucleoside bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "nucleoside bisphosphate metabolism" EXACT [] +is_a: GO:0006753 ! nucleoside phosphate metabolic process + +[Term] +id: GO:0033866 +name: nucleoside bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "nucleoside bisphosphate anabolism" EXACT [] +synonym: "nucleoside bisphosphate biosynthesis" EXACT [] +synonym: "nucleoside bisphosphate formation" EXACT [] +synonym: "nucleoside bisphosphatehate synthesis" EXACT [] +is_a: GO:0033865 ! nucleoside bisphosphate metabolic process +is_a: GO:1901293 ! nucleoside phosphate biosynthetic process + +[Term] +id: GO:0033867 +name: Fas-activated serine/threonine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein." [EC:2.7.11.8] +synonym: "ATP:Fas-activated serine/threonine protein phosphotransferase activity" EXACT [EC:2.7.11.8] +synonym: "FAST" RELATED [EC:2.7.11.8] +synonym: "FASTK" RELATED [EC:2.7.11.8] +synonym: "STK10" RELATED [EC:2.7.11.8] +xref: EC:2.7.11.8 +xref: MetaCyc:2.7.11.8-RXN +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0033868 +name: obsolete Goodpasture-antigen-binding protein kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein." [EC:2.7.11.9] +comment: This term was made obsolete because it represents a specific gene product. +synonym: "ATP:Goodpasture antigen-binding protein phosphotransferase activity" EXACT [EC:2.7.11.9] +synonym: "Goodpasture antigen-binding protein kinase activity" EXACT [EC:2.7.11.9] +synonym: "GPBP kinase activity" EXACT [EC:2.7.11.9] +synonym: "GPBPK" RELATED [EC:2.7.11.9] +synonym: "STK11" RELATED [EC:2.7.11.9] +xref: EC:2.7.11.9 +xref: MetaCyc:2.7.11.9-RXN +is_obsolete: true + +[Term] +id: GO:0033869 +name: nucleoside bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "nucleoside bisphosphate breakdown" EXACT [] +synonym: "nucleoside bisphosphate catabolism" EXACT [] +synonym: "nucleoside bisphosphate degradation" EXACT [] +is_a: GO:0033865 ! nucleoside bisphosphate metabolic process +is_a: GO:1901292 ! nucleoside phosphate catabolic process + +[Term] +id: GO:0033870 +name: thiol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate." [EC:2.8.2.16] +synonym: "3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity" EXACT [EC:2.8.2.16] +synonym: "adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity" EXACT [EC:2.8.2.16] +synonym: "PAPS sulfotransferase activity" BROAD [EC:2.8.2.16] +xref: EC:2.8.2.16 +xref: MetaCyc:THIOL-SULFOTRANSFERASE-RXN +xref: RHEA:14637 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0033871 +name: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S." [EC:2.8.2.29] +synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity" BROAD [EC:2.8.2.29] +synonym: "3-OST-2" RELATED [EC:2.8.2.29] +synonym: "glucosaminyl 3-O-sulfotransferase 2 activity" EXACT [EC:2.8.2.29] +synonym: "glucosaminyl 3-O-sulfotransferase activity" BROAD [EC:2.8.2.29] +synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity" EXACT [EC:2.8.2.29] +synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" BROAD [EC:2.8.2.29] +synonym: "heparin-glucosamine 3-sulfotransferase 2 activity" RELATED [] +synonym: "isoform/isozyme 2 (3-OST-2, HS3ST2)" RELATED [EC:2.8.2.29] +xref: EC:2.8.2.29 +xref: MetaCyc:2.8.2.29-RXN +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0033872 +name: [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate." [EC:2.8.2.30] +synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity" BROAD [EC:2.8.2.30] +synonym: "3-OST-3" RELATED [EC:2.8.2.30] +synonym: "glucosaminyl 3-O-sulfotransferase 3 activity" EXACT [EC:2.8.2.30] +synonym: "glucosaminyl 3-O-sulfotransferase 3a, 3b activity" EXACT [EC:2.8.2.30] +synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity" EXACT [EC:2.8.2.30] +synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity" EXACT [EC:2.8.2.30] +synonym: "heparin-glucosamine 3-sulfotransferase 3 activity" RELATED [] +synonym: "isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B)" RELATED [EC:2.8.2.30] +xref: EC:2.8.2.30 +xref: MetaCyc:2.8.2.30-RXN +is_a: GO:0034483 ! heparan sulfate sulfotransferase activity + +[Term] +id: GO:0033873 +name: petromyzonol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+)." [EC:2.8.2.31, RHEA:16997] +synonym: "3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity" EXACT [EC:2.8.2.31] +synonym: "PZ-SULT" RELATED [EC:2.8.2.31] +xref: EC:2.8.2.31 +xref: KEGG_REACTION:R07797 +xref: MetaCyc:2.8.2.31-RXN +xref: RHEA:16997 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0033874 +name: scymnol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+)." [EC:2.8.2.32, RHEA:15477] +xref: EC:2.8.2.32 +xref: KEGG_REACTION:R07798 +xref: MetaCyc:2.8.2.32-RXN +xref: RHEA:15477 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0033875 +name: ribonucleoside bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "ribonucleoside bisphosphate metabolism" EXACT [] +is_a: GO:0033865 ! nucleoside bisphosphate metabolic process + +[Term] +id: GO:0033876 +name: glycochenodeoxycholate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+)." [EC:2.8.2.34, RHEA:17689] +synonym: "3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity" EXACT [EC:2.8.2.34] +synonym: "BAST" RELATED [EC:2.8.2.34] +synonym: "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity" BROAD [EC:2.8.2.34] +synonym: "bile acid:PAPS:sulfotransferase activity" EXACT [EC:2.8.2.34] +xref: EC:2.8.2.34 +xref: KEGG_REACTION:R07289 +xref: MetaCyc:2.8.2.34-RXN +xref: RHEA:17689 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0033877 +name: succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity +namespace: molecular_function +alt_id: GO:0018728 +def: "Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate." [EC:2.8.3.15, RHEA:16469] +synonym: "benzylsuccinate CoA-transferase activity" EXACT [EC:2.8.3.15] +synonym: "succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity" EXACT [EC:2.8.3.15] +synonym: "succinyl-CoA:benzylsuccinate CoA-transferase activity" EXACT [] +xref: EC:2.8.3.15 +xref: KEGG_REACTION:R05588 +xref: MetaCyc:RXN-864 +xref: RHEA:16469 +xref: UM-BBD_reactionID:r0329 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0033878 +name: hormone-sensitive lipase activity +namespace: molecular_function +def: "Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate." [EC:3.1.1.79] +synonym: "diacylglycerol acylhydrolase activity" EXACT [EC:3.1.1.79] +synonym: "HSL" RELATED [EC:3.1.1.79] +xref: EC:3.1.1.79 +xref: MetaCyc:STEROL-ESTERASE-RXN +xref: MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0033879 +name: acetylajmaline esterase activity +namespace: molecular_function +def: "Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate." [EC:3.1.1.80] +synonym: "17-O-acetylajmaline O-acetylhydrolase activity" EXACT [EC:3.1.1.80] +synonym: "2beta(R)-17-O-acetylajmalan:acetylesterase activity" EXACT [EC:3.1.1.80] +synonym: "AAE" RELATED [EC:3.1.1.80] +synonym: "acetylajmalan esterase activity" EXACT [EC:3.1.1.80] +xref: EC:3.1.1.80 +xref: MetaCyc:RXN-8652 +xref: MetaCyc:RXN-8653 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0033880 +name: phenylacetyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate." [EC:3.1.2.25, RHEA:15337] +synonym: "phenylglyoxylyl-CoA hydrolase activity" EXACT [EC:3.1.2.25] +xref: EC:3.1.2.25 +xref: KEGG_REACTION:R07294 +xref: MetaCyc:3.1.2.25-RXN +xref: RHEA:15337 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0033881 +name: bile-acid-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+)." [EC:3.1.2.26, RHEA:17693] +synonym: "bile acid-coenzyme A hydrolase activity" EXACT [EC:3.1.2.26] +synonym: "deoxycholoyl-CoA hydrolase activity" EXACT [EC:3.1.2.26] +xref: EC:3.1.2.26 +xref: KEGG_REACTION:R07295 +xref: MetaCyc:BACOAHYDRO-RXN +xref: RHEA:17693 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0033882 +name: choloyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA." [EC:3.1.2.27] +synonym: "chenodeoxycholoyl-coenzyme A thioesterase activity" EXACT [EC:3.1.2.27] +synonym: "choloyl-coenzyme A thioesterase activity" EXACT [EC:3.1.2.27] +synonym: "peroxisomal acyl-CoA thioesterase 2 activity" NARROW [EC:3.1.2.27] +synonym: "PTE-2" RELATED [EC:3.1.2.27] +xref: EC:3.1.2.27 +xref: MetaCyc:3.1.2.27-RXN +xref: RHEA:14541 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0033883 +name: pyridoxal phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate." [EC:3.1.3.74] +synonym: "PLP phosphatase activity" EXACT [EC:3.1.3.74] +synonym: "PNP phosphatase activity" EXACT [EC:3.1.3.74] +synonym: "pyridoxal-5'-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.74] +synonym: "vitamin B6 (pyridoxine) phosphatase activity" BROAD [EC:3.1.3.74] +synonym: "vitamin B6-phosphate phosphatase activity" BROAD [EC:3.1.3.74] +xref: EC:3.1.3.74 +xref: MetaCyc:3.1.3.74-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0033884 +name: obsolete phosphoethanolamine/phosphocholine phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate." [EC:3.1.3.75] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "3X11A" RELATED [EC:3.1.3.75] +synonym: "PHOSPHO1" RELATED [EC:3.1.3.75] +synonym: "phosphoethanolamine phosphohydrolase activity" NARROW [EC:3.1.3.75] +synonym: "phosphoethanolamine/phosphocholine phosphatase activity" EXACT [] +is_obsolete: true +consider: GO:0052731 +consider: GO:0052732 + +[Term] +id: GO:0033885 +name: 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate." [EC:3.1.3.76, RHEA:16537] +synonym: "(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity" EXACT [EC:3.1.3.76] +synonym: "(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.76] +synonym: "dihydroxy fatty acid phosphatase activity" BROAD [EC:3.1.3.76] +synonym: "hydroxy fatty acid phosphatase activity" BROAD [EC:3.1.3.76] +synonym: "hydroxy lipid phosphatase activity" BROAD [EC:3.1.3.76] +synonym: "lipid-phosphate phosphatase activity" BROAD [EC:3.1.3.76] +synonym: "sEH" RELATED [EC:3.1.3.76] +synonym: "soluble epoxide hydrolase activity" RELATED [EC:3.1.3.76] +xref: EC:3.1.3.76 +xref: KEGG_REACTION:R07582 +xref: MetaCyc:3.1.3.76-RXN +xref: RHEA:16537 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0033886 +name: cellulose-polysulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin." [EC:3.1.6.7] +synonym: "cellulose-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.7] +xref: EC:3.1.6.7 +xref: MetaCyc:3.1.6.7-RXN +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0033887 +name: chondro-4-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate." [EC:3.1.6.9, RHEA:11444] +synonym: "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity" EXACT [EC:3.1.6.9] +xref: EC:3.1.6.9 +xref: KEGG_REACTION:R03517 +xref: MetaCyc:CHONDRO-4-SULFATASE-RXN +xref: RHEA:11444 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0033888 +name: chondro-6-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate." [EC:3.1.6.10, RHEA:10536] +synonym: "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity" EXACT [EC:3.1.6.10] +xref: EC:3.1.6.10 +xref: KEGG_REACTION:R03518 +xref: MetaCyc:CHONDRO-6-SULFATASE-RXN +xref: RHEA:10536 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0033889 +name: N-sulfoglucosamine-3-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin." [EC:3.1.6.15] +synonym: "chondroitinsulfatase activity" BROAD [EC:3.1.6.15] +synonym: "N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity" EXACT [EC:3.1.6.15] +xref: EC:3.1.6.15 +xref: MetaCyc:3.1.6.15-RXN +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0033890 +name: ribonuclease D activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides." [EC:3.1.13.5] +synonym: "RNase D activity" EXACT [EC:3.1.13.5] +xref: EC:3.1.13.5 +xref: MetaCyc:3.1.13.5-RXN +is_a: GO:0016896 ! exoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033891 +name: CC-preferring endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC." [EC:3.1.21.6] +synonym: "5'-CC-3'-preferring endodeoxyribonuclease activity" EXACT [EC:3.1.21.6] +synonym: "Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity" EXACT [EC:3.1.21.6] +synonym: "Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity" EXACT [EC:3.1.21.6] +synonym: "Streptomyces glaucescens exocytoplasmic endonuclease activity" EXACT [EC:3.1.21.6] +xref: EC:3.1.21.6 +xref: MetaCyc:3.1.21.6-RXN +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033892 +name: deoxyribonuclease (pyrimidine dimer) activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate." [EC:3.1.25.1] +synonym: "bacteriophage T4 endodeoxyribonuclease V activity" EXACT [EC:3.1.25.1] +synonym: "endodeoxyribonuclease (pyrimidine dimer) activity" EXACT [EC:3.1.25.1] +synonym: "T4 endonuclease V activity" EXACT [EC:3.1.25.1] +xref: EC:3.1.25.1 +xref: MetaCyc:3.1.25.1-RXN +is_a: GO:0016890 ! site-specific endodeoxyribonuclease activity, specific for altered base + +[Term] +id: GO:0033893 +name: ribonuclease IV activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.6] +synonym: "endoribonuclease IV activity" EXACT [EC:3.1.26.6] +xref: EC:3.1.26.6 +xref: MetaCyc:3.1.26.6-RXN +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033894 +name: ribonuclease P4 activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor." [EC:3.1.26.7] +xref: EC:3.1.26.7 +xref: MetaCyc:3.1.26.7-RXN +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033895 +name: ribonuclease [poly-(U)-specific] activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.9] +synonym: "ribonuclease (uracil-specific) activity" EXACT [EC:3.1.26.9] +synonym: "uracil-specific endoribonuclease activity" EXACT [EC:3.1.26.9] +synonym: "uracil-specific RNase activity" EXACT [EC:3.1.26.9] +xref: EC:3.1.26.9 +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033896 +name: ribonuclease IX activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.10] +synonym: "poly(U)- and poly(C)-specific endoribonuclease activity" EXACT [EC:3.1.26.10] +xref: EC:3.1.26.10 +xref: MetaCyc:3.1.26.10-RXN +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0033897 +name: ribonuclease T2 activity +namespace: molecular_function +def: "Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:4.6.1.19] +synonym: "acid ribonuclease activity" EXACT [] +synonym: "acid RNase activity" EXACT [] +synonym: "base-non-specific ribonuclease activity" EXACT [] +synonym: "Escherichia coli ribonuclease I' ribonuclease PP2 activity" EXACT [] +synonym: "Escherichia coli ribonuclease II activity" EXACT [EC:4.6.1.19] +synonym: "non-base specific ribonuclease activity" EXACT [] +synonym: "nonbase-specific RNase activity" EXACT [] +synonym: "nonspecific RNase activity" EXACT [] +synonym: "ribonnuclease (non-base specific) activity" EXACT [] +synonym: "ribonuclease (non-base specific) activity" EXACT [EC:3.1.27.1] +synonym: "ribonuclease II activity" BROAD [EC:4.6.1.19] +synonym: "ribonuclease M activity" EXACT [] +synonym: "ribonuclease N2 activity" EXACT [] +synonym: "ribonuclease PP3 activity" EXACT [EC:3.1.27.1] +synonym: "ribonuclease U4 activity" EXACT [] +synonym: "ribonucleate 3'-oligonucleotide hydrolase activity" EXACT [] +synonym: "ribonucleate nucleotido-2'-transferase (cyclizing) activity" BROAD [] +synonym: "RNAase CL activity" EXACT [] +synonym: "RNase (non-base specific) activity" EXACT [] +synonym: "RNase II activity" BROAD [EC:4.6.1.19] +synonym: "RNase M activity" EXACT [EC:3.1.27.1] +synonym: "RNase Ms activity" EXACT [] +synonym: "RNase T2 activity" EXACT [EC:4.6.1.19] +xref: EC:4.6.1.19 +xref: MetaCyc:3.1.27.1-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033898 +name: Bacillus subtilis ribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides." [EC:4.6.1.22] +synonym: "proteus mirabilis RNase activity" EXACT [] +synonym: "ribonucleate nucleotido-2'-transferase (cyclizing) activity" BROAD [] +xref: EC:4.6.1.22 +xref: MetaCyc:3.1.27.2-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033899 +name: ribonuclease U2 activity +namespace: molecular_function +def: "Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates." [EC:4.6.1.20] +synonym: "pleospora RNase activity" EXACT [] +synonym: "purine specific endoribonuclease activity" EXACT [] +synonym: "purine-specific ribonuclease activity" EXACT [] +synonym: "purine-specific RNase activity" EXACT [] +synonym: "ribonuclease (purine) activity" EXACT [] +synonym: "ribonuclease U2 activity" EXACT [EC:4.6.1.20] +synonym: "RNase U2 activity" EXACT [EC:4.6.1.20] +synonym: "trichoderma koningi RNase III activity" EXACT [] +xref: EC:4.6.1.20 +xref: MetaCyc:3.1.27.4-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033900 +name: ribonuclease F activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups." [EC:3.1.27.7] +synonym: "ribonuclease F (E. coli) activity" EXACT [EC:3.1.27.7] +synonym: "RNase F activity" EXACT [EC:3.1.27.7] +xref: EC:3.1.27.7 +xref: MetaCyc:3.1.27.7-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033901 +name: ribonuclease V activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP." [EC:3.1.27.8] +synonym: "endoribonuclease V activity" EXACT [EC:3.1.27.8] +xref: EC:3.1.27.8 +xref: MetaCyc:3.1.27.8-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033902 +name: rRNA endonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes." [EC:3.1.27.10] +synonym: "alpha-sarcin" RELATED [EC:3.1.27.10] +xref: EC:3.1.27.10 +xref: MetaCyc:3.1.27.10-RXN +is_a: GO:0016892 ! endoribonuclease activity, producing 3'-phosphomonoesters + +[Term] +id: GO:0033903 +name: obsolete endo-1,3(4)-beta-glucanase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6] +comment: This term was made obsolete because it was representing two different activities, for which new GO terms have now been created: GO:0052861 glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group and GO:0052862 glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group. +synonym: "1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity" EXACT [EC:3.2.1.6] +synonym: "beta-1,3-1,4-glucanase activity" EXACT [EC:3.2.1.6] +synonym: "beta-1,3-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-1,3(4)-beta-glucanase activity" EXACT [] +synonym: "endo-1,3-1,4-beta-D-glucanase activity" EXACT [EC:3.2.1.6] +synonym: "endo-1,3-beta-D-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-1,3-beta-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-1,4-beta-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-beta-(1,3)-D-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-beta-(1->3)-D-glucanase activity" BROAD [EC:3.2.1.6] +synonym: "endo-beta-1,3(4)-glucanase activity" EXACT [EC:3.2.1.6] +synonym: "endo-beta-1,3-1,4-glucanase activity" EXACT [EC:3.2.1.6] +synonym: "endo-beta-1,3-glucanase IV activity" EXACT [EC:3.2.1.6] +synonym: "laminaranase activity" BROAD [EC:3.2.1.6] +synonym: "laminarinase activity" BROAD [EC:3.2.1.6] +xref: EC:3.2.1.6 +xref: MetaCyc:3.2.1.6-RXN +is_obsolete: true +consider: GO:0052861 +consider: GO:0052862 + +[Term] +id: GO:0033904 +name: dextranase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran." [EC:3.2.1.11] +synonym: "1,6-alpha-D-glucan 6-glucanohydrolase activity" EXACT [EC:3.2.1.11] +synonym: "alpha-1,6-glucan-6-glucanohydrolase activity" EXACT [EC:3.2.1.11] +synonym: "alpha-D-1,6-glucan-6-glucanohydrolase activity" EXACT [EC:3.2.1.11] +synonym: "dextran hydrolase activity" EXACT [EC:3.2.1.11] +synonym: "dextranase DL 2 activity" NARROW [EC:3.2.1.11] +synonym: "DL 2" RELATED [EC:3.2.1.11] +synonym: "endo-dextranase activity" EXACT [EC:3.2.1.11] +synonym: "endodextranase activity" EXACT [EC:3.2.1.11] +xref: EC:3.2.1.11 +xref: MetaCyc:3.2.1.11-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033905 +name: xylan endo-1,3-beta-xylosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans." [EC:3.2.1.32] +synonym: "1,3-beta-D-xylan xylanohydrolase activity" EXACT [EC:3.2.1.32] +synonym: "1,3-beta-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "1,3-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "beta-1,3-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "endo-1,3-beta-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "endo-1,3-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "endo-beta-1,3-xylanase activity" EXACT [EC:3.2.1.32] +synonym: "xylanase activity" BROAD [EC:3.2.1.32] +xref: EC:3.2.1.32 +xref: MetaCyc:3.2.1.32-RXN +is_a: GO:0097599 ! xylanase activity + +[Term] +id: GO:0033906 +name: hyaluronoglucuronidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate." [EC:3.2.1.36] +synonym: "glucuronoglucosaminoglycan hyaluronate lyase activity" EXACT [EC:3.2.1.36] +synonym: "hyaluronate 3-glycanohydrolase activity" EXACT [EC:3.2.1.36] +synonym: "hyaluronidase activity" BROAD [EC:3.2.1.36] +synonym: "orgelase activity" EXACT [EC:3.2.1.36] +xref: EC:3.2.1.36 +xref: MetaCyc:3.2.1.36-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033907 +name: beta-D-fucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides." [EC:3.2.1.38] +synonym: "beta-D-fucoside fucohydrolase activity" EXACT [EC:3.2.1.38] +synonym: "beta-fucosidase activity" EXACT [EC:3.2.1.38] +xref: EC:3.2.1.38 +xref: MetaCyc:3.2.1.38-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033908 +name: beta-L-rhamnosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides." [EC:3.2.1.43] +synonym: "beta-L-rhamnoside rhamnohydrolase activity" EXACT [EC:3.2.1.43] +xref: EC:3.2.1.43 +xref: MetaCyc:3.2.1.43-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033909 +name: fucoidanase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate." [EC:3.2.1.44] +synonym: "poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity" EXACT [EC:3.2.1.44] +xref: EC:3.2.1.44 +xref: MetaCyc:3.2.1.44-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033910 +name: glucan 1,4-alpha-maltotetraohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends." [EC:3.2.1.60] +synonym: "1,4-alpha-D-glucan maltotetraohydrolase activity" EXACT [EC:3.2.1.60] +synonym: "exo-maltotetraohydrolase activity" EXACT [EC:3.2.1.60] +synonym: "G4-amylase activity" EXACT [EC:3.2.1.60] +synonym: "glucan 1,4-alpha-maltotetrahydrolase activity" EXACT [EC:3.2.1.60] +synonym: "maltotetraose-forming amylase activity" EXACT [EC:3.2.1.60] +xref: EC:3.2.1.60 +xref: MetaCyc:3.2.1.60-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033911 +name: mycodextranase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds." [EC:3.2.1.61] +synonym: "1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.61] +xref: EC:3.2.1.61 +xref: MetaCyc:3.2.1.61-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033912 +name: 2,6-beta-fructan 6-levanbiohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain." [EC:3.2.1.64] +synonym: "2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity" EXACT [EC:3.2.1.64] +synonym: "2,6-beta-D-fructan 6-levanbiohydrolase activity" EXACT [EC:3.2.1.64] +synonym: "2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity" EXACT [EC:3.2.1.64] +synonym: "beta-2,6-fructan-6-levanbiohydrolase activity" EXACT [EC:3.2.1.64] +synonym: "levanbiose-producing levanase activity" EXACT [EC:3.2.1.64] +xref: EC:3.2.1.64 +xref: MetaCyc:3.2.1.64-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033913 +name: glucan endo-1,2-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans." [EC:3.2.1.71] +synonym: "1,2-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.71] +synonym: "beta-D-1,2-glucanase activity" EXACT [EC:3.2.1.71] +synonym: "endo-(1->2)-beta-D-glucanase activity" EXACT [EC:3.2.1.71] +synonym: "endo-1,2-beta-glucanase activity" EXACT [EC:3.2.1.71] +xref: EC:3.2.1.71 +xref: MetaCyc:3.2.1.71-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0033914 +name: xylan 1,3-beta-xylosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans." [EC:3.2.1.72] +synonym: "1,3-beta-D-xylan xylohydrolase activity" EXACT [EC:3.2.1.72] +synonym: "1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity" EXACT [EC:3.2.1.72] +synonym: "beta-1,3'-xylanase activity" EXACT [EC:3.2.1.72] +synonym: "exo-1,3-beta-xylosidase activity" EXACT [EC:3.2.1.72] +synonym: "exo-beta-1,3'-xylanase activity" EXACT [EC:3.2.1.72] +xref: EC:3.2.1.72 +xref: MetaCyc:3.2.1.72-RXN +is_a: GO:0097599 ! xylanase activity + +[Term] +id: GO:0033915 +name: mannan 1,2-(1,3)-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose." [EC:3.2.1.77] +synonym: "1,2-1,3-alpha-D-mannan mannohydrolase activity" EXACT [EC:3.2.1.77] +synonym: "exo-1,2-1,3-alpha-mannosidase activity" EXACT [EC:3.2.1.77] +xref: EC:3.2.1.77 +xref: MetaCyc:3.2.1.77-RXN +is_a: GO:0004559 ! alpha-mannosidase activity + +[Term] +id: GO:0033916 +name: beta-agarase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product." [EC:3.2.1.81] +synonym: "AgaA" RELATED [EC:3.2.1.81] +synonym: "AgaB" RELATED [EC:3.2.1.81] +synonym: "agarase activity" BROAD [EC:3.2.1.81] +synonym: "agarose 3-glycanohydrolase activity" BROAD [EC:3.2.1.81] +synonym: "agarose 4-glycanohydrolase activity" EXACT [EC:3.2.1.81] +xref: EC:3.2.1.81 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033917 +name: exo-poly-alpha-galacturonosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate." [EC:3.2.1.82] +synonym: "exopolygalacturanosidase activity" EXACT [EC:3.2.1.82] +synonym: "exopolygalacturonosidase activity" EXACT [EC:3.2.1.82] +xref: EC:3.2.1.82 +xref: MetaCyc:3.2.1.82-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033918 +name: kappa-carrageenase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans." [EC:3.2.1.83] +synonym: "kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity" EXACT [EC:3.2.1.83] +synonym: "kappa-carrageenan 4-beta-D-glycanohydrolase activity" EXACT [EC:3.2.1.83] +xref: EC:3.2.1.83 +xref: MetaCyc:3.2.1.83-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033919 +name: glucan 1,3-alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans." [EC:3.2.1.84] +synonym: "1,3-alpha-D-glucan 3-glucohydrolase activity" EXACT [EC:3.2.1.84] +synonym: "exo-1,3-alpha-glucanase activity" EXACT [EC:3.2.1.84] +synonym: "glucosidase II activity" RELATED [EC:3.2.1.84, GOC:vw] +xref: EC:3.2.1.84 +xref: MetaCyc:3.2.1.84-RXN +xref: Reactome:R-HSA-532667 "Removal of the second glucose by glucosidase II" +xref: Reactome:R-HSA-548890 "Removal of the third glucose by glucosidase II and release from the chaperone" +is_a: GO:0090600 ! alpha-1,3-glucosidase activity + +[Term] +id: GO:0033920 +name: 6-phospho-beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol." [EC:3.2.1.85] +synonym: "6-phospho-beta-D-galactosidase activity" EXACT [EC:3.2.1.85] +synonym: "6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity" EXACT [EC:3.2.1.85] +synonym: "beta-D-phosphogalactoside galactohydrolase activity" EXACT [EC:3.2.1.85] +synonym: "phospho-beta-D-galactosidase activity" EXACT [EC:3.2.1.85] +synonym: "phospho-beta-galactosidase activity" EXACT [EC:3.2.1.85] +xref: EC:3.2.1.85 +xref: MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0033921 +name: capsular-polysaccharide endo-1,3-alpha-galactosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide." [EC:3.2.1.87] +synonym: "aerobacter-capsular-polysaccharide galactohydrolase activity" EXACT [EC:3.2.1.87] +synonym: "capsular polysaccharide galactohydrolase activity" EXACT [EC:3.2.1.87] +synonym: "polysaccharide depolymerase activity" EXACT [EC:3.2.1.87] +xref: EC:3.2.1.87 +xref: MetaCyc:3.2.1.87-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0033922 +name: peptidoglycan beta-N-acetylmuramidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues." [EC:3.2.1.92] +synonym: "beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity" EXACT [EC:3.2.1.92] +synonym: "exo-beta-acetylmuramidase activity" EXACT [EC:3.2.1.92] +synonym: "exo-beta-N-acetylmuramidase activity" EXACT [EC:3.2.1.92] +synonym: "peptidoglycan beta-N-acetylmuramoylexohydrolase activity" EXACT [EC:3.2.1.92] +xref: EC:3.2.1.92 +xref: MetaCyc:3.2.1.92-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033923 +name: glucan 1,6-alpha-isomaltosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains." [EC:3.2.1.94] +synonym: "1,6-alpha-D-glucan isomaltohydrolase activity" EXACT [EC:3.2.1.94] +synonym: "exo-isomaltohydrolase activity" EXACT [EC:3.2.1.94] +synonym: "G2-dextranase activity" EXACT [EC:3.2.1.94] +synonym: "isomalto-dextranase activity" EXACT [EC:3.2.1.94] +synonym: "isomaltodextranase activity" EXACT [EC:3.2.1.94] +xref: EC:3.2.1.94 +xref: MetaCyc:3.2.1.94-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033924 +name: dextran 1,6-alpha-isomaltotriosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains." [EC:3.2.1.95] +synonym: "1,6-alpha-D-glucan isomaltotriohydrolase activity" EXACT [EC:3.2.1.95] +synonym: "exo-isomaltotriohydrolase activity" EXACT [EC:3.2.1.95] +xref: EC:3.2.1.95 +xref: MetaCyc:3.2.1.95-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033925 +name: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact." [EC:3.2.1.96] +synonym: "di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-(1->4)-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-N-acetylglucosaminidase D activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-N-acetylglucosaminidase F activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-N-acetylglucosaminidase H activity" EXACT [EC:3.2.1.96] +synonym: "endo-beta-N-acetylglucosaminidase L activity" EXACT [EC:3.2.1.96] +synonym: "endo-N-acetyl-beta-D-glucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endo-N-acetyl-beta-glucosaminidase activity" EXACT [EC:3.2.1.96] +synonym: "endoglycosidase H activity" EXACT [EC:3.2.1.96] +synonym: "endoglycosidase S activity" EXACT [EC:3.2.1.96] +synonym: "glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" EXACT [EC:3.2.1.96] +synonym: "glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" EXACT [EC:3.2.1.96] +synonym: "mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity" EXACT [EC:3.2.1.96] +synonym: "mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity" EXACT [EC:3.2.1.96] +synonym: "N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] +xref: EC:3.2.1.96 +xref: MetaCyc:3.2.1.96-RXN +xref: Reactome:R-HSA-8853379 "ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5)" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033926 +name: glycopeptide alpha-N-acetylgalactosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins." [EC:3.2.1.97, MetaCyc:3.2.1.97-RXN] +synonym: "D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity" EXACT [EC:3.2.1.97] +synonym: "endo-alpha-acetylgalactosaminidase activity" BROAD [EC:3.2.1.97] +synonym: "endo-alpha-N-acetylgalactosaminidase activity" BROAD [EC:3.2.1.97] +xref: EC:3.2.1.97 +xref: MetaCyc:3.2.1.97-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0033927 +name: glucan 1,4-alpha-maltohexaosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends." [EC:3.2.1.98] +synonym: "1,4-alpha-D-glucan maltohexaohydrolase activity" EXACT [EC:3.2.1.98] +synonym: "exo-maltohexaohydrolase activity" EXACT [EC:3.2.1.98] +synonym: "G6-amylase activity" EXACT [EC:3.2.1.98] +synonym: "maltohexaose-producing amylase activity" EXACT [EC:3.2.1.98] +xref: EC:3.2.1.98 +xref: MetaCyc:3.2.1.98-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033928 +name: mannan 1,4-mannobiosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends." [EC:3.2.1.100] +synonym: "1,4-beta-D-mannan mannobiohydrolase activity" BROAD [EC:3.2.1.100] +synonym: "exo-1,4-beta-mannobiohydrolase activity" EXACT [EC:3.2.1.100] +synonym: "exo-beta-mannanase activity" EXACT [EC:3.2.1.100] +synonym: "mannan 1,4-beta-mannobiosidase activity" EXACT [EC:3.2.1.100] +xref: EC:3.2.1.100 +xref: MetaCyc:3.2.1.100-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033929 +name: blood-group-substance endo-1,4-beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances." [EC:3.2.1.102] +synonym: "blood-group-substance 1,4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.102] +synonym: "endo-beta-galactosidase activity" BROAD [EC:3.2.1.102] +xref: EC:3.2.1.102 +xref: MetaCyc:3.2.1.102-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0033930 +name: keratan-sulfate endo-1,4-beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate." [EC:3.2.1.103] +synonym: "endo-beta-galactosidase activity" BROAD [EC:3.2.1.103] +synonym: "keratan sulfate endogalactosidase activity" EXACT [EC:3.2.1.103] +synonym: "keratan-sulfate 1,4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.103] +synonym: "keratanase activity" EXACT [EC:3.2.1.103] +xref: EC:3.2.1.103 +xref: MetaCyc:3.2.1.103-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0033931 +name: endogalactosaminidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine)." [EC:3.2.1.109] +synonym: "galactosaminoglycan glycanohydrolase activity" EXACT [EC:3.2.1.109] +xref: EC:3.2.1.109 +xref: MetaCyc:3.2.1.109-RXN +is_a: GO:0015929 ! hexosaminidase activity + +[Term] +id: GO:0033932 +name: 1,3-alpha-L-fucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins." [EC:3.2.1.111] +synonym: "3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity" EXACT [EC:3.2.1.111] +synonym: "almond emulsin fucosidase I activity" EXACT [EC:3.2.1.111] +xref: EC:3.2.1.111 +xref: MetaCyc:3.2.1.111-RXN +is_a: GO:0004560 ! alpha-L-fucosidase activity + +[Term] +id: GO:0033933 +name: branched-dextran exo-1,2-alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose." [EC:3.2.1.115] +synonym: "1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity" EXACT [EC:3.2.1.115] +synonym: "dextran 1,2-alpha-glucosidase activity" EXACT [EC:3.2.1.115] +synonym: "dextran alpha-1,2 debranching enzyme" RELATED [EC:3.2.1.115] +xref: EC:3.2.1.115 +xref: MetaCyc:3.2.1.115-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0033934 +name: glucan 1,4-alpha-maltotriohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends." [EC:3.2.1.116] +synonym: "1,4-alpha-D-glucan maltotriohydrolase activity" EXACT [EC:3.2.1.116] +synonym: "exo-maltotriohydrolase activity" EXACT [EC:3.2.1.116] +synonym: "maltotriohydrolase activity" EXACT [EC:3.2.1.116] +xref: EC:3.2.1.116 +xref: MetaCyc:3.2.1.116-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033935 +name: oligoxyloglucan beta-glycosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends." [EC:3.2.1.120] +synonym: "isoprimeverose-producing oligoxyloglucan hydrolase activity" EXACT [EC:3.2.1.120] +synonym: "oligoxyloglucan hydrolase activity" EXACT [EC:3.2.1.120] +synonym: "oligoxyloglucan xyloglucohydrolase activity" EXACT [EC:3.2.1.120] +xref: EC:3.2.1.120 +xref: MetaCyc:3.2.1.120-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0033936 +name: polymannuronate hydrolase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate." [EC:3.2.1.121] +synonym: "poly(mannuronide) mannuronohydrolase activity" EXACT [EC:3.2.1.121] +synonym: "polymannuronic acid polymerase activity" EXACT [EC:3.2.1.121] +xref: EC:3.2.1.121 +xref: MetaCyc:3.2.1.121-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033937 +name: 3-deoxy-2-octulosonidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides." [EC:3.2.1.124] +synonym: "2-keto-3-deoxyoctonate hydrolase activity" EXACT [EC:3.2.1.124] +synonym: "capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity" EXACT [EC:3.2.1.124] +synonym: "octulofuranosylono hydrolase activity" EXACT [EC:3.2.1.124] +synonym: "octulopyranosylonohydrolase activity" EXACT [EC:3.2.1.124] +synonym: "octulosylono hydrolase activity" EXACT [EC:3.2.1.124] +xref: EC:3.2.1.124 +xref: MetaCyc:3.2.1.124-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033938 +name: 1,6-alpha-L-fucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin." [EC:3.2.1.127] +synonym: "1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity" EXACT [EC:3.2.1.127] +xref: EC:3.2.1.127 +xref: MetaCyc:3.2.1.127-RXN +is_a: GO:0004560 ! alpha-L-fucosidase activity + +[Term] +id: GO:0033939 +name: xylan alpha-1,2-glucuronosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans." [EC:3.2.1.131] +synonym: "1,2-alpha-glucuronidase activity" EXACT [EC:3.2.1.131] +synonym: "alpha-(1->2)-glucuronidase activity" EXACT [EC:3.2.1.131] +synonym: "xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity" EXACT [EC:3.2.1.131] +xref: EC:3.2.1.131 +xref: MetaCyc:3.2.1.131-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033940 +name: glucuronoarabinoxylan endo-1,4-beta-xylanase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans." [EC:3.2.1.136] +synonym: "endoarabinoxylanase activity" EXACT [EC:3.2.1.136] +synonym: "feraxan endoxylanase activity" EXACT [EC:3.2.1.136] +synonym: "feraxanase activity" EXACT [EC:3.2.1.136] +synonym: "glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity" EXACT [EC:3.2.1.136] +synonym: "glucuronoxylan xylanohydrolase activity" EXACT [EC:3.2.1.136] +synonym: "glucuronoxylan xylohydrolase activity" EXACT [EC:3.2.1.136] +synonym: "glucuronoxylanase activity" EXACT [EC:3.2.1.136] +xref: EC:3.2.1.136 +xref: MetaCyc:3.2.1.136-RXN +is_a: GO:0097599 ! xylanase activity + +[Term] +id: GO:0033941 +name: mannan exo-1,2-1,6-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose." [EC:3.2.1.137] +synonym: "1,2-1,6-alpha-D-mannan D-mannohydrolase activity" EXACT [EC:3.2.1.137] +synonym: "exo-1,2-1,6-alpha-mannosidase activity" EXACT [EC:3.2.1.137] +xref: EC:3.2.1.137 +xref: MetaCyc:3.2.1.137-RXN +is_a: GO:0004559 ! alpha-mannosidase activity + +[Term] +id: GO:0033942 +name: 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan." [EC:3.2.1.141] +synonym: "4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity" EXACT [EC:3.2.1.141] +synonym: "4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity" EXACT [EC:3.2.1.141] +synonym: "malto-oligosyltrehalose trehalohydrolase activity" EXACT [EC:3.2.1.141] +synonym: "maltooligosyl trehalose trehalohydrolase activity" EXACT [EC:3.2.1.141] +xref: EC:3.2.1.141 +xref: MetaCyc:3.2.1.141-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033943 +name: galactan 1,3-beta-galactosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans." [EC:3.2.1.145] +synonym: "galactan (1,3)-beta-D-galactosidase activity" EXACT [EC:3.2.1.145] +synonym: "galactan (1->3)-beta-D-galactosidase activity" EXACT [EC:3.2.1.145] +xref: EC:3.2.1.145 +xref: MetaCyc:3.2.1.145-RXN +is_a: GO:0015925 ! galactosidase activity + +[Term] +id: GO:0033944 +name: beta-galactofuranosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose." [EC:3.2.1.146] +synonym: "beta-D-galactofuranosidase activity" EXACT [EC:3.2.1.146] +synonym: "beta-D-galactofuranoside hydrolase activity" EXACT [EC:3.2.1.146] +synonym: "exo-beta-D-galactofuranosidase activity" EXACT [EC:3.2.1.146] +synonym: "exo-beta-galactofuranosidase activity" EXACT [EC:3.2.1.146] +xref: EC:3.2.1.146 +xref: MetaCyc:3.2.1.146-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033945 +name: oligoxyloglucan reducing-end-specific cellobiohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted." [EC:3.2.1.150] +synonym: "oligoxyloglucan reducing end-specific cellobiohydrolase activity" EXACT [EC:3.2.1.150] +synonym: "oligoxyloglucan reducing-end cellobiohydrolase activity" EXACT [EC:3.2.1.150] +xref: EC:3.2.1.150 +xref: MetaCyc:3.2.1.150-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033946 +name: xyloglucan-specific endo-beta-1,4-glucanase activity +namespace: molecular_function +def: "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan." [EC:3.2.1.151] +synonym: "1,4-beta-D-glucan glucanohydrolase activity" BROAD [EC:3.2.1.151] +synonym: "[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.151] +synonym: "XEG" RELATED [EC:3.2.1.151] +synonym: "XH" RELATED [EC:3.2.1.151] +synonym: "xyloglucan endo-beta-1,4-glucanase activity" EXACT [EC:3.2.1.151] +synonym: "xyloglucanase activity" EXACT [EC:3.2.1.151] +synonym: "xyloglucanendohydrolase activity" EXACT [EC:3.2.1.151] +xref: EC:3.2.1.151 +xref: MetaCyc:3.2.1.151-RXN +is_a: GO:0052736 ! beta-glucanase activity + +[Term] +id: GO:0033947 +name: mannosylglycoprotein endo-beta-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences." [EC:3.2.1.152] +synonym: "endo-beta-mannosidase activity" EXACT [EC:3.2.1.152] +xref: EC:3.2.1.152 +xref: MetaCyc:3.2.1.152-RXN +is_a: GO:0004567 ! beta-mannosidase activity + +[Term] +id: GO:0033948 +name: fructan beta-(2,1)-fructosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.153] +synonym: "1-FEH II" RELATED [EC:3.2.1.153] +synonym: "1-FEH w1" RELATED [EC:3.2.1.153] +synonym: "1-FEH w2" RELATED [EC:3.2.1.153] +synonym: "1-fructan exohydrolase activity" EXACT [EC:3.2.1.153] +synonym: "beta-(2,1)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.153] +synonym: "beta-(2,1)-fructan exohydrolase activity" EXACT [EC:3.2.1.153] +synonym: "beta-(2,1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153] +xref: EC:3.2.1.153 +xref: MetaCyc:3.2.1.153-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033949 +name: fructan beta-(2,6)-fructosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.154] +synonym: "6-FEH" RELATED [EC:3.2.1.154] +synonym: "beta-(2,6)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.154] +synonym: "beta-(2,6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154] +xref: EC:3.2.1.154 +xref: MetaCyc:3.2.1.154-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033950 +name: xyloglucan-specific exo-beta-1,4-glucanase activity +namespace: molecular_function +def: "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan." [EC:3.2.1.155] +synonym: "[(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity" EXACT [EC:3.2.1.155] +synonym: "Cel74A" RELATED [EC:3.2.1.155] +xref: EC:3.2.1.155 +xref: MetaCyc:3.2.1.155-RXN +is_a: GO:0052736 ! beta-glucanase activity + +[Term] +id: GO:0033951 +name: oligosaccharide reducing-end xylanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides." [EC:3.2.1.156] +synonym: "beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity" EXACT [EC:3.2.1.156] +synonym: "reducing end xylose-releasing exo-oligoxylanase activity" EXACT [EC:3.2.1.156] +synonym: "Rex" RELATED [EC:3.2.1.156] +xref: EC:3.2.1.156 +xref: MetaCyc:3.2.1.156-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033952 +name: iota-carrageenase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans." [EC:3.2.1.157] +synonym: "iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity" EXACT [EC:3.2.1.157] +xref: EC:3.2.1.157 +xref: MetaCyc:3.2.1.157-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033953 +name: alpha-agarase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product." [EC:3.2.1.158] +synonym: "agarase A33 activity" NARROW [EC:3.2.1.158] +synonym: "agarase activity" BROAD [EC:3.2.1.158] +synonym: "agarose 3-glycanohydrolase activity" BROAD [EC:3.2.1.158] +xref: EC:3.2.1.158 +xref: MetaCyc:3.2.1.158-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033954 +name: alpha-neoagaro-oligosaccharide hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose." [EC:3.2.1.159] +synonym: "alpha-NAOS hydrolase activity" EXACT [EC:3.2.1.159] +synonym: "alpha-neoagaro-oligosaccharide 3-glycohydrolase activity" EXACT [EC:3.2.1.159] +synonym: "alpha-neoagarooligosaccharide hydrolase activity" EXACT [EC:3.2.1.159] +xref: EC:3.2.1.159 +xref: MetaCyc:3.2.1.159-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033955 +name: mitochondrial DNA inheritance +namespace: biological_process +alt_id: GO:0090142 +def: "The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission." [GOC:mah] +synonym: "mitochondrial chromosome segregation" RELATED [] +synonym: "mitochondrial DNA segregation" RELATED [] +is_a: GO:0000002 ! mitochondrial genome maintenance +relationship: part_of GO:0000266 ! mitochondrial fission + +[Term] +id: GO:0033956 +name: beta-apiosyl-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose." [EC:3.2.1.161] +synonym: "7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity" EXACT [EC:3.2.1.161] +synonym: "furcatin hydrolase activity" EXACT [EC:3.2.1.161] +synonym: "isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity" EXACT [EC:3.2.1.161] +synonym: "isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity" EXACT [EC:3.2.1.161] +xref: EC:3.2.1.161 +xref: MetaCyc:3.2.1.161-RXN +xref: MetaCyc:RXN-9156 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0033957 +name: lambda-carrageenase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S." [EC:3.2.1.162] +synonym: "endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity" EXACT [EC:3.2.1.162] +xref: EC:3.2.1.162 +xref: MetaCyc:3.2.1.162-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0033958 +name: DNA-deoxyinosine glycosylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine." [EC:3.2.2.15] +synonym: "deoxyribonucleic acid glycosylase activity" EXACT [EC:3.2.2.15] +synonym: "DNA(hypoxanthine) glycohydrolase activity" EXACT [EC:3.2.2.15] +synonym: "DNA-deoxyinosine deoxyribohydrolase activity" EXACT [EC:3.2.2.15] +synonym: "DNA-deoxyinosine glycosidase activity" EXACT [EC:3.2.2.15] +synonym: "hypoxanthine-DNA glycosylase activity" EXACT [EC:3.2.2.15] +xref: EC:3.2.2.15 +xref: MetaCyc:3.2.2.15-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0033959 +name: deoxyribodipyrimidine endonucleosidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue." [EC:3.2.2.17] +synonym: "deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity" EXACT [EC:3.2.2.17] +synonym: "deoxyribonucleate pyrimidine dimer glycosidase activity" EXACT [EC:3.2.2.17] +synonym: "endonuclease V activity" BROAD [EC:3.2.2.17] +synonym: "PD-DNA glycosylase activity" EXACT [EC:3.2.2.17] +synonym: "pyrimidine dimer DNA glycosylase activity" EXACT [EC:3.2.2.17] +synonym: "pyrimidine dimer DNA-glycosylase activity" EXACT [EC:3.2.2.17] +synonym: "T4-induced UV endonuclease activity" EXACT [EC:3.2.2.17] +xref: EC:3.2.2.17 +xref: MetaCyc:3.2.2.17-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0033960 +name: N-methyl nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose." [EC:3.2.2.25, RHEA:10880] +synonym: "7-methylxanthosine nucleosidase activity" EXACT [EC:3.2.2.25] +synonym: "7-methylxanthosine ribohydrolase activity" EXACT [EC:3.2.2.25] +synonym: "methylpurine nucleosidase activity" EXACT [EC:3.2.2.25] +synonym: "N-MeNase activity" EXACT [EC:3.2.2.25] +synonym: "N-methyl nucleoside hydrolase activity" EXACT [EC:3.2.2.25] +xref: EC:3.2.2.25 +xref: KEGG_REACTION:R07918 +xref: MetaCyc:RXN-7597 +xref: RHEA:10880 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0033961 +name: cis-stilbene-oxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol." [EC:3.3.2.9] +subset: goslim_chembl +synonym: "arene-oxide hydratase activity" BROAD [EC:3.3.2.9] +synonym: "aryl epoxide hydrase activity" BROAD [EC:3.3.2.9] +synonym: "benzo(a)pyrene-4,5-epoxide hydratase activity" NARROW [EC:3.3.2.9] +synonym: "benzo[a]pyrene-4,5-oxide hydratase activity" NARROW [EC:3.3.2.9] +synonym: "cis-epoxide hydrolase activity" EXACT [EC:3.3.2.9] +synonym: "epoxide hydrase activity" BROAD [EC:3.3.2.9] +synonym: "epoxide hydratase activity" BROAD [EC:3.3.2.9] +synonym: "mEH" RELATED [EC:3.3.2.9] +synonym: "microsomal epoxide hydrase activity" NARROW [EC:3.3.2.9] +synonym: "microsomal epoxide hydratase activity" NARROW [EC:3.3.2.9] +synonym: "microsomal epoxide hydrolase activity" NARROW [EC:3.3.2.9] +xref: EC:3.3.2.9 +xref: MetaCyc:3.3.2.9-RXN +xref: Reactome:R-HSA-5694077 "EPHX1 hydrates BaP4,5O to BaP4,5-DHD" +xref: RHEA:23900 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0033962 +name: cytoplasmic mRNA processing body assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body." [GOC:mah, PMID:17429074] +synonym: "P body assembly" EXACT [] +synonym: "P body biogenesis" RELATED [] +synonym: "P-body assembly" EXACT [] +is_a: GO:0070925 ! organelle assembly + +[Term] +id: GO:0033963 +name: cholesterol-5,6-oxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol." [EC:3.3.2.11] +synonym: "5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity" EXACT [EC:3.3.2.11] +synonym: "ChEH" RELATED [EC:3.3.2.11] +synonym: "cholesterol-epoxide hydrolase activity" EXACT [EC:3.3.2.11] +xref: EC:3.3.2.11 +xref: MetaCyc:RXN-8650 +xref: MetaCyc:RXN-8651 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0033964 +name: glycosphingolipid deacylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives." [EC:3.5.1.69] +synonym: "glycosphingolipid amidohydrolase activity" EXACT [EC:3.5.1.69] +synonym: "glycosphingolipid ceramide deacylase activity" BROAD [EC:3.5.1.69] +xref: EC:3.5.1.69 +xref: MetaCyc:3.5.1.69-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033965 +name: aculeacin-A deacylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain." [EC:3.5.1.70] +synonym: "aculeacin A acylase activity" EXACT [EC:3.5.1.70] +synonym: "aculeacin-A amidohydrolase activity" EXACT [EC:3.5.1.70] +xref: EC:3.5.1.70 +xref: MetaCyc:3.5.1.70-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033966 +name: N-substituted formamide deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine." [EC:3.5.1.91] +synonym: "N-benzylformamide amidohydrolase activity" EXACT [EC:3.5.1.91] +synonym: "NfdA" RELATED [EC:3.5.1.91] +xref: MetaCyc:3.5.1.91-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033967 +name: box C/D snoRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving box C/D type small nucleolar RNA." [GOC:mah] +is_a: GO:0016074 ! snoRNA metabolic process + +[Term] +id: GO:0033968 +name: glutaryl-7-aminocephalosporanic-acid acylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate." [EC:3.5.1.93] +synonym: "(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity" EXACT [EC:3.5.1.93] +synonym: "7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity" EXACT [EC:3.5.1.93] +synonym: "CA" RELATED [EC:3.5.1.93] +synonym: "cephalosporin acylase activity" EXACT [EC:3.5.1.93] +synonym: "cephalosporin C acylase activity" EXACT [EC:3.5.1.93] +synonym: "GA" RELATED [EC:3.5.1.93] +synonym: "GCA" RELATED [EC:3.5.1.93] +synonym: "GL-7-ACA acylase activity" EXACT [EC:3.5.1.93] +synonym: "glutaryl-7-ACA acylase activity" EXACT [EC:3.5.1.93] +synonym: "glutaryl-7-aminocephalosporanic acid acylase activity" EXACT [EC:3.5.1.93] +xref: EC:3.5.1.93 +xref: MetaCyc:3.5.1.93-RXN +xref: RHEA:23508 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033969 +name: gamma-glutamyl-gamma-aminobutyrate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate." [EC:3.5.1.94, RHEA:19737] +synonym: "4-(glutamylamino)butanoate amidohydrolase activity" EXACT [EC:3.5.1.94] +synonym: "gamma-glutamyl-GABA hydrolase activity" EXACT [EC:3.5.1.94] +synonym: "PuuD" RELATED [EC:3.5.1.94] +synonym: "YcjL" RELATED [EC:3.5.1.94] +xref: EC:3.5.1.94 +xref: KEGG_REACTION:R07419 +xref: MetaCyc:RXN0-3942 +xref: RHEA:19737 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033970 +name: N-malonylurea hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea." [EC:3.5.1.95, RHEA:17361] +synonym: "3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity" EXACT [EC:3.5.1.95] +synonym: "ureidomalonase activity" EXACT [EC:3.5.1.95] +xref: EC:3.5.1.95 +xref: KEGG_REACTION:R07629 +xref: MetaCyc:3.5.1.95-RXN +xref: RHEA:17361 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0033971 +name: hydroxyisourate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)." [EC:3.5.2.17, RHEA:23736] +synonym: "5-hydroxyisourate amidohydrolase activity" EXACT [EC:3.5.2.17] +synonym: "5-hydroxyisourate hydrolase activity" EXACT [EC:3.5.2.17] +synonym: "HIUHase activity" EXACT [EC:3.5.2.17] +xref: EC:3.5.2.17 +xref: KEGG_REACTION:R06601 +xref: MetaCyc:3.5.2.17-RXN +xref: RHEA:23736 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0033972 +name: proclavaminate amidinohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea." [EC:3.5.3.22, RHEA:17001] +synonym: "PAH" RELATED [EC:3.5.3.22] +synonym: "proclavaminate amidino hydrolase activity" EXACT [EC:3.5.3.22] +synonym: "proclavaminic acid amidino hydrolase activity" EXACT [EC:3.5.3.22] +xref: EC:3.5.3.22 +xref: KEGG_REACTION:R05357 +xref: MetaCyc:3.5.3.22-RXN +xref: RHEA:17001 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0033973 +name: dCTP deaminase (dUMP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+)." [EC:3.5.4.30, RHEA:19205] +synonym: "dCTP aminohydrolase (dUMP-forming) activity" EXACT [EC:3.5.4.30] +xref: EC:3.5.4.30 +xref: KEGG_REACTION:R07307 +xref: MetaCyc:3.5.4.30-RXN +xref: RHEA:19205 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0033974 +name: nucleoside phosphoacylhydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of mixed phospho-anhydride bonds." [EC:3.6.1.24] +synonym: "nucleoside-5'-phosphoacylate acylhydrolase activity" EXACT [EC:3.6.1.24] +xref: EC:3.6.1.24 +xref: MetaCyc:3.6.1.24-RXN +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0033975 +name: (R)-2-haloacid dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide." [EC:3.8.1.9] +synonym: "(R)-2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.9] +synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.9] +synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.9] +synonym: "D-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.9] +synonym: "D-DEX" RELATED [EC:3.8.1.9] +xref: EC:3.8.1.9 +xref: MetaCyc:3.8.1.9-RXN +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0033976 +name: 2-haloacid dehalogenase (configuration-inverting) activity +namespace: molecular_function +def: "Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide." [EC:3.8.1.10] +synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.10] +synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.10] +synonym: "DL-2-haloacid dehalogenase (inversion of configuration) activity" EXACT [EC:3.8.1.10] +synonym: "DL-2-haloacid dehalogenase activity" BROAD [EC:3.8.1.10] +synonym: "DL-2-haloacid halidohydrolase (inversion of configuration) activity" EXACT [EC:3.8.1.10] +synonym: "DL-DEXi" RELATED [EC:3.8.1.10] +xref: EC:3.8.1.10 +xref: MetaCyc:3.8.1.10-RXN +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0033977 +name: 2-haloacid dehalogenase (configuration-retaining) activity +namespace: molecular_function +def: "Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide." [EC:3.8.1.11] +synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.11] +synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.11] +synonym: "DL-2-haloacid dehalogenase activity" BROAD [EC:3.8.1.11] +synonym: "DL-DEXr" RELATED [EC:3.8.1.11] +xref: EC:3.8.1.11 +xref: MetaCyc:3.8.1.11-RXN +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0033978 +name: phosphonopyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate." [EC:3.11.1.3, RHEA:16673] +synonym: "PPH" RELATED [EC:3.11.1.3] +xref: EC:3.11.1.3 +xref: KEGG_REACTION:R08200 +xref: MetaCyc:3.11.1.3-RXN +xref: RHEA:16673 +is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds + +[Term] +id: GO:0033979 +name: box H/ACA snoRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving box H/ACA type small nucleolar RNA." [GOC:mah] +is_a: GO:0016074 ! snoRNA metabolic process + +[Term] +id: GO:0033980 +name: phosphonopyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde." [EC:4.1.1.82, RHEA:20768] +synonym: "3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity" EXACT [EC:4.1.1.82] +synonym: "3-phosphonopyruvate carboxy-lyase activity" EXACT [EC:4.1.1.82] +xref: EC:4.1.1.82 +xref: KEGG_REACTION:R04053 +xref: MetaCyc:4.1.1.82-RXN +xref: RHEA:20768 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0033981 +name: D-dopachrome decarboxylase activity +namespace: molecular_function +alt_id: GO:0030928 +def: "Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2)." [EC:4.1.1.84, RHEA:18441] +synonym: "D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity" EXACT [EC:4.1.1.84] +synonym: "D-dopachrome carboxy-lyase activity" EXACT [EC:4.1.1.84] +synonym: "D-dopachrome tautomerase activity" EXACT [EC:4.1.1.84] +synonym: "D-tautomerase activity" EXACT [EC:4.1.1.84] +synonym: "dopachrome conversion activity" BROAD [] +synonym: "dopachrome decarboxylase activity" EXACT [] +synonym: "phenylpyruvate tautomerase II activity" EXACT [EC:4.1.1.84] +xref: EC:4.1.1.84 +xref: KEGG_REACTION:R07313 +xref: MetaCyc:4.1.1.84-RXN +xref: RHEA:18441 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0033982 +name: 3-dehydro-L-gulonate-6-phosphate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2)." [EC:4.1.1.85, RHEA:14353] +synonym: "3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity" EXACT [EC:4.1.1.85] +synonym: "3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.85] +synonym: "3-keto-L-gulonate 6-phosphate decarboxylase activity" EXACT [EC:4.1.1.85] +synonym: "KGPDC" RELATED [EC:4.1.1.85] +synonym: "SgaH" RELATED [EC:4.1.1.85] +synonym: "SgbH" RELATED [EC:4.1.1.85] +synonym: "UlaD" RELATED [EC:4.1.1.85] +xref: EC:4.1.1.85 +xref: KEGG_REACTION:R07125 +xref: MetaCyc:RXN0-705 +xref: RHEA:14353 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0033983 +name: diaminobutyrate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2)." [EC:4.1.1.86, RHEA:15689] +synonym: "DABA DC" RELATED [EC:4.1.1.86] +synonym: "L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity" EXACT [EC:4.1.1.86] +synonym: "L-2,4-diaminobutanoate carboxy-lyase activity" EXACT [EC:4.1.1.86] +synonym: "L-2,4-diaminobutyrate decarboxylase activity" EXACT [EC:4.1.1.86] +xref: EC:4.1.1.86 +xref: KEGG_REACTION:R07650 +xref: MetaCyc:4.1.1.86-RXN +xref: RHEA:15689 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0033984 +name: indole-3-glycerol-phosphate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate." [EC:4.1.2.8] +synonym: "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity" EXACT [EC:4.1.2.8] +synonym: "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.8] +synonym: "BX1" RELATED [EC:4.1.2.8] +synonym: "IGL" RELATED [EC:4.1.2.8] +synonym: "indole glycerol phosphate hydrolase activity" EXACT [EC:4.1.2.8] +synonym: "indole synthase activity" EXACT [EC:4.1.2.8] +synonym: "indole-3-glycerol phosphate lyase activity" EXACT [EC:4.1.2.8] +synonym: "indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.8] +synonym: "indoleglycerolphosphate aldolase activity" EXACT [EC:4.1.2.8] +synonym: "tryptophan synthase alpha activity" NARROW [EC:4.1.2.8] +synonym: "tryptophan synthase alpha subunit activity" NARROW [EC:4.1.2.8] +synonym: "TSA" RELATED [EC:4.1.2.8] +xref: EC:4.1.2.8 +xref: KEGG_REACTION:R02340 +xref: MetaCyc:4.1.2.8-RXN +xref: MetaCyc:RXN0-2381 +xref: RHEA:14081 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0033985 +name: acidocalcisome lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of an acidocalcisome." [GOC:mah] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0020022 ! acidocalcisome + +[Term] +id: GO:0033986 +name: response to methanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus." [GOC:sl] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0097305 ! response to alcohol + +[Term] +id: GO:0033987 +name: 2-hydroxyisoflavanone dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O." [EC:4.2.1.105] +synonym: "2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity" EXACT [EC:4.2.1.105] +synonym: "2,7,4'-trihydroxyisoflavanone hydro-lyase activity" EXACT [EC:4.2.1.105] +xref: EC:4.2.1.105 +xref: MetaCyc:RXN-3284 +xref: RHEA:16445 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033988 +name: bile-acid 7alpha-dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O." [EC:4.2.1.106, RHEA:10436] +synonym: "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity" EXACT [EC:4.2.1.106] +synonym: "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity" EXACT [EC:4.2.1.106] +synonym: "BA7 alpha dehydratase activity" EXACT [EC:4.2.1.106] +xref: EC:4.2.1.106 +xref: KEGG_REACTION:R07318 +xref: MetaCyc:4.2.1.106-RXN +xref: RHEA:10436 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033989 +name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O." [EC:4.2.1.107] +synonym: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity" EXACT [EC:4.2.1.107] +synonym: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.107] +synonym: "46 kDa hydratase 2 activity" EXACT [EC:4.2.1.107] +synonym: "D-3-hydroxyacyl-CoA dehydratase activity" BROAD [EC:4.2.1.107] +xref: EC:4.2.1.107 +xref: MetaCyc:4.2.1.107-RXN +xref: Reactome:R-HSA-192331 "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA" +xref: Reactome:R-HSA-193535 "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA" +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033990 +name: ectoine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O." [EC:4.2.1.108, RHEA:17281] +synonym: "4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity" EXACT [EC:4.2.1.108] +synonym: "EctC" RELATED [EC:4.2.1.108] +synonym: "L-ectoine synthase activity" EXACT [EC:4.2.1.108] +synonym: "N-acetyldiaminobutanoate dehydratase activity" EXACT [EC:4.2.1.108] +synonym: "N-acetyldiaminobutyrate dehydratase activity" EXACT [EC:4.2.1.108] +synonym: "N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity" EXACT [EC:4.2.1.108] +xref: EC:4.2.1.108 +xref: KEGG_REACTION:R06979 +xref: MetaCyc:R103-RXN +xref: RHEA:17281 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033991 +name: aldos-2-ulose dehydratase activity +namespace: molecular_function +def: "Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one." [EC:4.2.1.110] +synonym: "1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity" EXACT [EC:4.2.1.110] +synonym: "1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity" EXACT [EC:4.2.1.110] +synonym: "AUDH" RELATED [EC:4.2.1.110] +synonym: "pyranosone dehydratase activity" EXACT [EC:4.2.1.110] +xref: EC:4.2.1.110 +xref: MetaCyc:4.2.1.110-RXN +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033992 +name: 1,5-anhydro-D-fructose dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O." [EC:4.2.1.111] +synonym: "1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity" EXACT [EC:4.2.1.111] +synonym: "1,5-anhydro-D-fructose 4-dehydratase activity" EXACT [EC:4.2.1.111] +synonym: "1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity" EXACT [EC:4.2.1.111] +synonym: "1,5-anhydro-D-fructose hydro-lyase activity" EXACT [EC:4.2.1.111] +synonym: "1,5-anhydro-D-fructose hydrolyase activity" EXACT [EC:4.2.1.111] +synonym: "AF dehydratase activity" EXACT [EC:4.2.1.111] +synonym: "AFDH" RELATED [EC:4.2.1.111] +xref: EC:4.2.1.111 +xref: MetaCyc:4.2.1.111-RXN +xref: RHEA:15725 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0033993 +name: response to lipid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0033994 +name: glucuronan lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides." [EC:4.2.2.14] +synonym: "(1,4)-beta-D-glucuronan lyase activity" EXACT [EC:4.2.2.14] +xref: EC:4.2.2.14 +xref: MetaCyc:4.2.2.14-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0033995 +name: anhydrosialidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate." [EC:4.2.2.15] +synonym: "anhydroneuraminidase activity" EXACT [EC:4.2.2.15] +synonym: "glycoconjugate sialyl-lyase (2,7-cyclizing) activity" EXACT [EC:4.2.2.15] +synonym: "sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity" EXACT [EC:4.2.2.15] +synonym: "sialidase L activity" EXACT [EC:4.2.2.15] +xref: EC:4.2.2.15 +xref: MetaCyc:4.2.2.15-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0033996 +name: levan fructotransferase (DFA-IV-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.16] +synonym: "2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity" EXACT [EC:4.2.2.16] +synonym: "2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity" EXACT [EC:4.2.2.16] +synonym: "levan fructotransferase activity" EXACT [EC:4.2.2.16] +xref: EC:4.2.2.16 +xref: MetaCyc:4.2.2.16-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0033997 +name: inulin fructotransferase (DFA-I-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.17] +synonym: "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity" EXACT [EC:4.2.2.17] +synonym: "inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity" EXACT [EC:4.2.2.17] +synonym: "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity" EXACT [EC:4.2.2.17] +synonym: "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity" EXACT [EC:4.2.2.17] +synonym: "inulin fructotransferase (DFA-I-producing) activity" EXACT [EC:4.2.2.17] +xref: EC:4.2.2.17 +xref: MetaCyc:4.2.2.17-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0033998 +name: inulin fructotransferase (DFA-III-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.18] +synonym: "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] +synonym: "inulase II activity" EXACT [EC:4.2.2.18] +synonym: "inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] +synonym: "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity" EXACT [EC:4.2.2.18] +synonym: "inulin fructotransferase (depolymerizing) activity" EXACT [EC:4.2.2.18] +synonym: "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] +synonym: "inulin fructotransferase (DFA-III-producing) activity" EXACT [EC:4.2.2.18] +synonym: "inulinase II activity" EXACT [EC:4.2.2.18] +xref: EC:4.2.2.18 +xref: MetaCyc:4.2.2.18-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0033999 +name: chondroitin B lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate." [EC:4.2.2.19] +synonym: "ChnB" RELATED [EC:4.2.2.19] +synonym: "chonB" RELATED [EC:4.2.2.19] +synonym: "chondroitinase B activity" EXACT [EC:4.2.2.19] +synonym: "dermatan sulfate lyase activity" EXACT [] +xref: EC:4.2.2.19 +xref: MetaCyc:4.2.2.19-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0034000 +name: chondroitin-sulfate-ABC endolyase activity +namespace: molecular_function +def: "Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides." [EC:4.2.2.20] +synonym: "chondroitin ABC eliminase activity" BROAD [EC:4.2.2.20] +synonym: "chondroitin sulfate ABC endoeliminase activity" EXACT [EC:4.2.2.20] +synonym: "chondroitin sulfate ABC endolyase activity" EXACT [EC:4.2.2.20] +synonym: "chondroitin sulfate ABC lyase activity" BROAD [EC:4.2.2.20] +synonym: "chondroitinase ABC activity" BROAD [EC:4.2.2.20] +synonym: "chondroitinase activity" BROAD [EC:4.2.2.20] +synonym: "ChS ABC lyase activity" BROAD [EC:4.2.2.20] +synonym: "ChS ABC lyase I activity" EXACT [EC:4.2.2.20] +xref: EC:4.2.2.20 +xref: MetaCyc:4.2.2.20-RXN +is_a: GO:0047486 ! chondroitin ABC lyase activity + +[Term] +id: GO:0034001 +name: chondroitin-sulfate-ABC exolyase activity +namespace: molecular_function +def: "Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments." [EC:4.2.2.21] +synonym: "chondroitin ABC eliminase activity" BROAD [EC:4.2.2.21] +synonym: "chondroitin sulfate ABC exoeliminase activity" EXACT [EC:4.2.2.21] +synonym: "chondroitin sulfate ABC exolyase activity" EXACT [EC:4.2.2.21] +synonym: "chondroitin sulfate ABC lyase activity" BROAD [EC:4.2.2.21] +synonym: "chondroitinase ABC activity" BROAD [EC:4.2.2.21] +synonym: "chondroitinase activity" BROAD [EC:4.2.2.21] +synonym: "ChS ABC lyase activity" BROAD [EC:4.2.2.21] +synonym: "ChS ABC lyase II activity" EXACT [EC:4.2.2.21] +xref: EC:4.2.2.21 +xref: MetaCyc:4.2.2.21-RXN +is_a: GO:0047486 ! chondroitin ABC lyase activity + +[Term] +id: GO:0034002 +name: (R)-limonene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate." [EC:4.2.3.20, RHEA:10940] +synonym: "(+)-limonene synthase activity" EXACT [EC:4.2.3.20] +synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity" EXACT [EC:4.2.3.20] +synonym: "geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity" EXACT [EC:4.2.3.20] +xref: EC:4.2.3.20 +xref: KEGG_REACTION:R06120 +xref: MetaCyc:4.2.3.20-RXN +xref: RHEA:10940 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0034003 +name: vetispiradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene." [EC:4.2.3.21, RHEA:10340] +synonym: "HVS" RELATED [EC:4.2.3.21] +synonym: "pemnaspirodiene synthase activity" EXACT [EC:4.2.3.21] +synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity" EXACT [EC:4.2.3.21] +synonym: "vetispiradiene cyclase activity" EXACT [EC:4.2.3.21] +synonym: "vetispiradiene-forming farnesyl pyrophosphate cyclase activity" EXACT [EC:4.2.3.21] +xref: EC:4.2.3.21 +xref: KEGG_REACTION:R06523 +xref: MetaCyc:RXN-4823 +xref: RHEA:10340 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0034004 +name: germacradienol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate." [EC:4.2.3.22] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity" EXACT [EC:4.2.3.22] +xref: EC:4.2.3.22 +xref: KEGG_REACTION:R07647 +xref: MetaCyc:RXN-8648 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034005 +name: germacrene-A synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate." [EC:4.2.3.23, RHEA:12516] +synonym: "(+)-(10R)-germacrene A synthase activity" EXACT [EC:4.2.3.23] +synonym: "(+)-germacrene A synthase activity" EXACT [EC:4.2.3.23] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity" EXACT [EC:4.2.3.23] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity" EXACT [EC:4.2.3.23] +synonym: "GAS" RELATED [EC:4.2.3.23] +synonym: "germacrene A synthase activity" EXACT [EC:4.2.3.23] +xref: EC:4.2.3.23 +xref: KEGG_REACTION:R07649 +xref: MetaCyc:4.2.3.23-RXN +xref: RHEA:12516 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0034006 +name: amorpha-4,11-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate." [EC:4.2.3.24, RHEA:18325] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity" EXACT [EC:4.2.3.24] +synonym: "amorphadiene synthase activity" EXACT [EC:4.2.3.24] +xref: EC:4.2.3.24 +xref: KEGG_REACTION:R07630 +xref: MetaCyc:4.2.3.24-RXN +xref: MetaCyc:RXN-8046 +xref: RHEA:18325 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0034007 +name: S-linalool synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate." [EC:4.2.3.25, RHEA:24116] +synonym: "3S-linalool synthase activity" EXACT [EC:4.2.3.25] +synonym: "geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity" EXACT [EC:4.2.3.25] +synonym: "LIS" RELATED [EC:4.2.3.25] +xref: EC:4.2.3.25 +xref: KEGG_REACTION:R07631 +xref: MetaCyc:4.2.3.25-RXN +xref: RHEA:24116 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034008 +name: R-linalool synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate." [EC:4.2.3.26, RHEA:15809] +synonym: "(-)-3R-linalool synthase activity" EXACT [EC:4.2.3.26] +synonym: "(3R)-linalool synthase activity" EXACT [EC:4.2.3.26] +synonym: "geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity" EXACT [EC:4.2.3.26] +xref: EC:4.2.3.26 +xref: KEGG_REACTION:R07632 +xref: MetaCyc:4.2.3.26-RXN +xref: RHEA:15809 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034009 +name: isoprene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene." [EC:4.2.3.27, RHEA:13369] +synonym: "dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity" EXACT [EC:4.2.3.27] +synonym: "ISPC" RELATED [EC:4.2.3.27] +synonym: "ISPS" RELATED [EC:4.2.3.27] +xref: EC:4.2.3.27 +xref: KEGG_REACTION:R08199 +xref: MetaCyc:4.2.3.27-RXN +xref: RHEA:13369 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0034010 +name: sulfolactate sulfo-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite." [EC:4.4.1.24, RHEA:21428] +synonym: "3-sulfolactate bisulfite-lyase (pyruvate-forming) activity" EXACT [EC:4.4.1.24] +synonym: "3-sulfolactate bisulfite-lyase activity" EXACT [EC:4.4.1.24] +synonym: "Suy" RELATED [EC:4.4.1.24] +synonym: "SuyAB" RELATED [EC:4.4.1.24] +xref: EC:4.4.1.24 +xref: KEGG_REACTION:R07633 +xref: MetaCyc:4.4.1.24-RXN +xref: RHEA:21428 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0034011 +name: L-cysteate sulfo-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite." [EC:4.4.1.25, RHEA:13441] +synonym: "CuyA" RELATED [EC:4.4.1.25] +synonym: "L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity" EXACT [EC:4.4.1.25] +synonym: "L-cysteate sulfo-lyase (deaminating) activity" EXACT [EC:4.4.1.25] +xref: EC:4.4.1.25 +xref: KEGG_REACTION:R07634 +xref: MetaCyc:4.4.1.25-RXN +xref: RHEA:13441 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0034012 +name: FAD-AMP lyase (cyclizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate." [EC:4.6.1.15] +synonym: "FAD AMP-lyase (cyclic-FMN-forming) activity" EXACT [EC:4.6.1.15] +synonym: "FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity" EXACT [EC:4.6.1.15] +synonym: "FMN cyclase activity" EXACT [EC:4.6.1.15] +xref: EC:4.6.1.15 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016849 ! phosphorus-oxygen lyase activity + +[Term] +id: GO:0034013 +name: aliphatic aldoxime dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O." [EC:4.99.1.5] +synonym: "aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity" EXACT [EC:4.99.1.5] +synonym: "aliphatic aldoxime hydro-lyase activity" EXACT [EC:4.99.1.5] +synonym: "OxdA" RELATED [EC:4.99.1.5] +xref: EC:4.99.1.5 +xref: MetaCyc:4.99.1.5-RXN +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0034014 +name: response to triglyceride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus." [GOC:sl] +synonym: "response to triacylglyceride" EXACT [] +synonym: "response to triacylglycerol" EXACT [] +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0034015 +name: L-ribulose-5-phosphate 3-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate." [EC:5.1.3.22] +synonym: "L-xylulose 5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.22] +synonym: "SgaU" RELATED [EC:5.1.3.22] +synonym: "UlaE" RELATED [EC:5.1.3.22] +xref: EC:5.1.3.22 +xref: MetaCyc:LXULRU5P-RXN +xref: RHEA:18497 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0034016 +name: polyenoic fatty acid isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate." [EC:5.3.3.13, RHEA:14889] +synonym: "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity" EXACT [EC:5.3.3.13] +synonym: "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity" EXACT [EC:5.3.3.13] +synonym: "(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity" EXACT [EC:5.3.3.13] +synonym: "eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity" EXACT [EC:5.3.3.13] +synonym: "PFI" RELATED [EC:5.3.3.13] +xref: EC:5.3.3.13 +xref: KEGG_REACTION:R06502 +xref: MetaCyc:5.3.3.13-RXN +xref: RHEA:14889 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0034017 +name: trans-2-decenoyl-acyl-carrier-protein isomerase activity +namespace: molecular_function +alt_id: GO:0043832 +def: "Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein]." [EC:5.3.3.14] +synonym: "beta-hydroxydecanoyl thioester dehydrase activity" BROAD [EC:5.3.3.14] +synonym: "decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity" EXACT [EC:5.3.3.14] +synonym: "FabM" RELATED [EC:5.3.3.14] +synonym: "trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity" EXACT [] +synonym: "trans-2, cis-3 decenoyl-ACP isomerase activity" EXACT [] +synonym: "trans-2,cis-3-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] +synonym: "trans-2-cis-3-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] +synonym: "trans-2-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] +xref: EC:5.3.3.14 +xref: MetaCyc:5.3.3.14-RXN +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0034018 +name: ascopyrone tautomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose." [EC:5.3.2.7] +synonym: "1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity" EXACT [EC:5.3.2.7] +synonym: "1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity" EXACT [EC:5.3.2.7] +synonym: "APM tautomerase activity" EXACT [EC:5.3.2.7] +synonym: "APTM" RELATED [EC:5.3.2.7] +synonym: "ascopyrone intramolecular oxidoreductase activity" EXACT [EC:5.3.2.7] +synonym: "ascopyrone isomerase activity" EXACT [EC:5.3.2.7] +synonym: "ascopyrone P tautomerase activity" EXACT [EC:5.3.2.7] +xref: EC:5.3.2.7 +xref: MetaCyc:5.3.3.15-RXN +xref: RHEA:22568 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0034019 +name: obsolete capsanthin/capsorubin synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: violaxanthin = capsorubin, and antheraxanthin = capsanthin." [EC:5.3.99.8] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "capsanthin-capsorubin synthase activity" EXACT [EC:5.3.99.8] +synonym: "capsanthin/capsorubin synthase activity" EXACT [] +synonym: "CCS" RELATED [EC:5.3.99.8] +synonym: "ketoxanthophyll synthase activity" BROAD [EC:5.3.99.8] +synonym: "violaxanthin-capsorubin isomerase (ketone-forming) activity" NARROW [EC:5.3.99.8] +is_obsolete: true +consider: GO:0052727 +consider: GO:0052728 + +[Term] +id: GO:0034020 +name: neoxanthin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin." [EC:5.3.99.9, RHEA:10128] +synonym: "NSY" RELATED [EC:5.3.99.9] +synonym: "violaxanthin-neoxanthin isomerase (epoxide-opening) activity" EXACT [EC:5.3.99.9] +xref: EC:5.3.99.9 +xref: KEGG_REACTION:R06948 +xref: MetaCyc:RXN1F-155 +xref: RHEA:10128 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0034021 +name: response to silicon dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus." [GOC:sl] +synonym: "response to silica" EXACT [] +synonym: "response to silox" EXACT [] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0034022 +name: 3-(hydroxyamino)phenol mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone." [EC:5.4.4.3, RHEA:20577] +synonym: "3-(hydroxyamino)phenol hydroxymutase activity" EXACT [EC:5.4.4.3] +synonym: "3-hydroxylaminophenol mutase activity" EXACT [EC:5.4.4.3] +synonym: "3HAP mutase activity" EXACT [EC:5.4.4.3] +xref: EC:5.4.4.3 +xref: KEGG_REACTION:R06988 +xref: MetaCyc:5.4.4.3-RXN +xref: RHEA:20577 +xref: UM-BBD_enzymeID:e0953 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0034023 +name: 5-(carboxyamino)imidazole ribonucleotide mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate." [EC:5.4.99.18] +synonym: "5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity" EXACT [EC:5.4.99.18] +synonym: "class I PurE" RELATED [EC:5.4.99.18] +synonym: "N5-CAIR mutase activity" EXACT [EC:5.4.99.18] +synonym: "N5-carboxyaminoimidazole ribonucleotide mutase activity" EXACT [EC:5.4.99.18] +synonym: "PurE" RELATED [EC:5.4.99.18] +xref: EC:5.4.99.18 +xref: MetaCyc:5.4.99.18-RXN +xref: RHEA:13193 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0034024 +name: glutamate-putrescine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate." [EC:6.3.1.11, RHEA:13633] +synonym: "gamma-glutamylputrescine synthetase activity" EXACT [EC:6.3.1.11] +synonym: "L-glutamate:putrescine ligase (ADP-forming) activity" EXACT [EC:6.3.1.11] +synonym: "YcjK" RELATED [EC:6.3.1.11] +xref: EC:6.3.1.11 +xref: KEGG_REACTION:R07414 +xref: MetaCyc:RXN0-3901 +xref: RHEA:13633 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0034025 +name: D-aspartate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate." [EC:6.3.1.12] +synonym: "aslfm" RELATED [EC:6.3.1.12] +synonym: "D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity" EXACT [EC:6.3.1.12] +synonym: "D-aspartic acid-activating enzyme" RELATED [EC:6.3.1.12] +synonym: "UDP-MurNAc-pentapeptide:D-aspartate ligase activity" EXACT [EC:6.3.1.12] +xref: EC:6.3.1.12 +xref: MetaCyc:6.3.1.12-RXN +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0034026 +name: L-amino-acid alpha-ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid." [EC:6.3.2.49] +synonym: "bacilysin synthetase activity" EXACT [] +synonym: "L-amino acid alpha-ligase activity" EXACT [] +synonym: "L-amino acid ligase activity" EXACT [] +synonym: "YwfE" RELATED [] +xref: EC:6.3.2.49 +xref: MetaCyc:6.3.2.28-RXN +xref: RHEA:44332 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0034027 +name: (carboxyethyl)arginine beta-lactam-synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+)." [EC:6.3.3.4, RHEA:23620] +synonym: "beta-lactam synthetase activity" EXACT [EC:6.3.3.4] +synonym: "L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity" EXACT [EC:6.3.3.4] +synonym: "L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity" EXACT [EC:6.3.3.4] +xref: EC:6.3.3.4 +xref: KEGG_REACTION:R05467 +xref: MetaCyc:6.3.3.4-RXN +xref: RHEA:23620 +is_a: GO:0016882 ! cyclo-ligase activity + +[Term] +id: GO:0034028 +name: 5-(carboxyamino)imidazole ribonucleotide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate." [EC:6.3.4.18, RHEA:19317] +synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity" EXACT [EC:6.3.4.18] +synonym: "N5-CAIR synthetase activity" EXACT [EC:6.3.4.18] +synonym: "N5-carboxyaminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.4.18] +synonym: "PurK" RELATED [EC:6.3.4.18] +xref: EC:6.3.4.18 +xref: KEGG_REACTION:R07404 +xref: MetaCyc:RXN0-742 +xref: RHEA:19317 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0034029 +name: 2-oxoglutarate carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate." [EC:6.4.1.7, RHEA:20425] +synonym: "carboxylating factor for ICDH" RELATED [EC:6.4.1.7] +synonym: "CFI" RELATED [EC:6.4.1.7] +synonym: "OGC" RELATED [EC:6.4.1.7] +synonym: "oxalosuccinate synthetase activity" EXACT [EC:6.4.1.7] +xref: EC:6.4.1.7 +xref: KEGG_REACTION:R08201 +xref: MetaCyc:RXN-8457 +xref: RHEA:20425 +is_a: GO:0016885 ! ligase activity, forming carbon-carbon bonds + +[Term] +id: GO:0034030 +name: ribonucleoside bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "ribonucleoside bisphosphate anabolism" EXACT [] +synonym: "ribonucleoside bisphosphate biosynthesis" EXACT [] +synonym: "ribonucleoside bisphosphate formation" EXACT [] +synonym: "ribonucleoside bisphosphate synthesis" EXACT [] +is_a: GO:0033866 ! nucleoside bisphosphate biosynthetic process +is_a: GO:0033875 ! ribonucleoside bisphosphate metabolic process + +[Term] +id: GO:0034031 +name: ribonucleoside bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "ribonucleoside bisphosphate breakdown" EXACT [] +synonym: "ribonucleoside bisphosphate catabolism" EXACT [] +synonym: "ribonucleoside bisphosphate degradation" EXACT [] +is_a: GO:0033869 ! nucleoside bisphosphate catabolic process +is_a: GO:0033875 ! ribonucleoside bisphosphate metabolic process + +[Term] +id: GO:0034032 +name: purine nucleoside bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine nucleoside bisphosphate metabolism" EXACT [] +is_a: GO:0033865 ! nucleoside bisphosphate metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0034033 +name: purine nucleoside bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine nucleoside bisphosphate anabolism" EXACT [] +synonym: "purine nucleoside bisphosphate biosynthesis" EXACT [] +synonym: "purine nucleoside bisphosphate formation" EXACT [] +synonym: "purine nucleoside bisphosphate synthesis" EXACT [] +is_a: GO:0033866 ! nucleoside bisphosphate biosynthetic process +is_a: GO:0034032 ! purine nucleoside bisphosphate metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0034034 +name: purine nucleoside bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine nucleoside bisphosphate breakdown" EXACT [] +synonym: "purine nucleoside bisphosphate catabolism" EXACT [] +synonym: "purine nucleoside bisphosphate degradation" EXACT [] +is_a: GO:0033869 ! nucleoside bisphosphate catabolic process +is_a: GO:0034032 ! purine nucleoside bisphosphate metabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0034035 +name: purine ribonucleoside bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine ribonucleoside bisphosphate metabolism" EXACT [] +is_a: GO:0033875 ! ribonucleoside bisphosphate metabolic process +is_a: GO:0034032 ! purine nucleoside bisphosphate metabolic process + +[Term] +id: GO:0034036 +name: purine ribonucleoside bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine ribonucleoside bisphosphate anabolism" EXACT [] +synonym: "purine ribonucleoside bisphosphate biosynthesis" EXACT [] +synonym: "purine ribonucleoside bisphosphate formation" EXACT [] +synonym: "purine ribonucleoside bisphosphate synthesis" EXACT [] +is_a: GO:0034030 ! ribonucleoside bisphosphate biosynthetic process +is_a: GO:0034033 ! purine nucleoside bisphosphate biosynthetic process +is_a: GO:0034035 ! purine ribonucleoside bisphosphate metabolic process + +[Term] +id: GO:0034037 +name: purine ribonucleoside bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar." [GOC:mah, GOC:pde] +synonym: "purine ribonucleoside bisphosphate breakdown" EXACT [] +synonym: "purine ribonucleoside bisphosphate catabolism" EXACT [] +synonym: "purine ribonucleoside bisphosphate degradation" EXACT [] +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0034035 ! purine ribonucleoside bisphosphate metabolic process + +[Term] +id: GO:0034038 +name: deoxyhypusine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+." [EC:2.5.1.46, GOC:pde, MetaCyc:2.5.1.46-RXN] +comment: Note that this term is equivalent to the obsolete molecular function term 'deoxyhypusine synthase activity ; GO:0004171' and corresponds closely to the biological process term 'deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase ; GO:0050983'. +synonym: "eIF-5A-deoxyhypusine synthase activity" EXACT [EC:2.5.1.46] +synonym: "eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity" EXACT [EC:2.5.1.46] +synonym: "spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity" EXACT [EC:2.5.1.46] +xref: EC:2.5.1.46 +xref: MetaCyc:2.5.1.46-RXN +xref: Reactome:R-HSA-204617 "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A" +xref: Reactome:R-HSA-204647 "DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0034039 +name: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar." [GOC:mah, PMID:17641464] +synonym: "8-oxoG DNA N-glycosylase activity" EXACT [] +is_a: GO:0008534 ! oxidized purine nucleobase lesion DNA N-glycosylase activity + +[Term] +id: GO:0034040 +name: ATPase-coupled lipid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out)." [GOC:BHF, GOC:rl] +synonym: "ATP-dependent lipid transmembrane transporter activity" EXACT [] +synonym: "lipid-transporting ATPase activity" BROAD [] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0034041 +name: ATPase-coupled sterol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out)." [GOC:BHF, GOC:rl] +synonym: "ATP-coupled sterol transmembrane transporter activity" EXACT [] +synonym: "ATP-dependent sterol transmembrane transporter activity" RELATED [] +synonym: "sterol-transporting ATPase activity" RELATED [] +is_a: GO:0015248 ! sterol transporter activity +is_a: GO:0034040 ! ATPase-coupled lipid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity + +[Term] +id: GO:0034042 +name: 5-formyluracil DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar." [GOC:mah, PMID:17641464] +synonym: "5-foU DNA N-glycosylase activity" EXACT [] +is_a: GO:0000703 ! oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity + +[Term] +id: GO:0034043 +name: 5-hydroxymethyluracil DNA N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar." [GOC:mah, PMID:17641464] +synonym: "5-hmU DNA N-glycosylase activity" EXACT [] +is_a: GO:0000703 ! oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity + +[Term] +id: GO:0034044 +name: exomer complex +namespace: cellular_component +def: "A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues." [PMID:16498409, PMID:17000877] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0030140 ! trans-Golgi network transport vesicle + +[Term] +id: GO:0034045 +name: phagophore assembly site membrane +namespace: cellular_component +def: "A cellular membrane associated with the phagophore assembly site." [GOC:mah, GOC:rph, PMID:16874040, PMID:17382324] +synonym: "isolation membrane" RELATED [] +synonym: "PAS membrane" EXACT [] +synonym: "phagophore" RELATED [PMID:20811355] +synonym: "pre-autophagosomal structure membrane" NARROW [] +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0000407 ! phagophore assembly site + +[Term] +id: GO:0034046 +name: poly(G) binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule." [GOC:mah] +synonym: "poly(G) binding, within an RNA molecule" EXACT [] +synonym: "poly(rG) binding" EXACT [GOC:mah] +is_a: GO:0070717 ! poly-purine tract binding + +[Term] +id: GO:0034050 +name: host programmed cell death induced by symbiont +namespace: biological_process +def: "Cell death in a host resulting from activation of host endogenous cellular processes after direct or indirect interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). An example of direct interaction is contact with penetrating hyphae of a fungus; an example of indirect interaction is encountering symbiont-secreted molecules." [GOC:pamgo_curators] +comment: Note that this term is to be used to annotate gene products in the host, not the symbiont. To annotate gene products in the symbiont that induce programmed cell death in the host, consider the biological process term 'induction by symbiont of host programmed cell death ; GO:0052044'. +is_a: GO:0012501 ! programmed cell death + +[Term] +id: GO:0034051 +name: negative regulation of plant-type hypersensitive response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant." [GOC:pamgo_curators] +synonym: "down regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "down-regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "downregulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "inhibition of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "negative regulation of HR" EXACT [GOC:pamgo_curators] +synonym: "negative regulation of HR-PCD" EXACT [GOC:pamgo_curators] +synonym: "negative regulation of plant hypersensitive response" EXACT [GOC:pamgo_curators] +is_a: GO:0010363 ! regulation of plant-type hypersensitive response +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0045824 ! negative regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009626 ! plant-type hypersensitive response +relationship: negatively_regulates GO:0009626 ! plant-type hypersensitive response + +[Term] +id: GO:0034052 +name: positive regulation of plant-type hypersensitive response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant." [GOC:pamgo_curators] +synonym: "activation of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "positive regulation of HR" EXACT [GOC:pamgo_curators] +synonym: "positive regulation of HR-PCD" RELATED [GOC:pamgo_curators] +synonym: "positive regulation of plant hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "stimulation of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "up regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "up-regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +synonym: "upregulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] +is_a: GO:0010363 ! regulation of plant-type hypersensitive response +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:0045089 ! positive regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009626 ! plant-type hypersensitive response +relationship: positively_regulates GO:0009626 ! plant-type hypersensitive response + +[Term] +id: GO:0034053 +name: modulation by symbiont of host defense-related programmed cell death +namespace: biological_process +def: "Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'plant-type hypersensitive response ; GO:0009626'. +synonym: "modulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] +synonym: "modulation by symbiont of host HR" NARROW [GOC:pamgo_curators] +synonym: "modulation by symbiont of host hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "modulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] +synonym: "modulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] +is_a: GO:0052031 ! modulation by symbiont of host defense response +is_a: GO:0052040 ! modulation by symbiont of host programmed cell death + +[Term] +id: GO:0034054 +name: suppression by symbiont of host defense-related programmed cell death +namespace: biological_process +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of plant-type hypersensitive response ; GO:0034051'. +synonym: "down regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +synonym: "down-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +synonym: "downregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +synonym: "inhibition by symbiont of host defense-related PCD" NARROW [GOC:pamgo_curators] +synonym: "inhibition by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] +synonym: "inhibition of host defense-related PCD" NARROW [GOC:pamgo_curators] +synonym: "inhibition of HR" NARROW [GOC:pamgo_curators] +synonym: "inhibition of hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "negative regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] +synonym: "negative regulation by symbiont of host defense-related programmed cell death" EXACT [] +synonym: "negative regulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] +synonym: "negative regulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "suppression by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] +synonym: "suppression of HR" NARROW [GOC:pamgo_curators] +is_a: GO:0034053 ! modulation by symbiont of host defense-related programmed cell death +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052041 ! negative regulation by symbiont of host programmed cell death + +[Term] +id: GO:0034055 +name: positive regulation by symbiont of host defense-related programmed cell death +namespace: biological_process +def: "Any process in which a symbiont activates or increases the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of plant-type hypersensitive response ; GO:0034052'. +synonym: "activation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] +synonym: "activation of HR" NARROW [GOC:pamgo_curators] +synonym: "activation of hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "enhancement by symbiont of host defense-related PCDprogrammed cell death" NARROW [GOC:pamgo_curators] +synonym: "positive regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] +synonym: "positive regulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] +synonym: "positive regulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] +synonym: "stimulation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] +synonym: "up regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +synonym: "up-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +synonym: "upregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] +is_a: GO:0034053 ! modulation by symbiont of host defense-related programmed cell death +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052042 ! positive regulation by symbiont of host programmed cell death + +[Term] +id: GO:0034056 +name: estrogen response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen." [GOC:ecd, PMID:15036253, PMID:17975005] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "ERE binding" EXACT [] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding + +[Term] +id: GO:0034057 +name: RNA strand-exchange activity +namespace: molecular_function +def: "Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity." [GOC:mcc, PMID:9769100] +is_a: GO:0003725 ! double-stranded RNA binding +is_a: GO:0003727 ! single-stranded RNA binding + +[Term] +id: GO:0034058 +name: endosomal vesicle fusion +namespace: biological_process +def: "The homotypic fusion of endocytic vesicles to form or add to an early endosome." [PMID:11964142, PMID:9422733] +synonym: "endosome vesicle fusion" EXACT [] +is_a: GO:0006906 ! vesicle fusion + +[Term] +id: GO:0034059 +name: response to anoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." [GOC:kmv] +comment: Note that this term should not be confused with 'response to hypoxia ; GO:0001666'. +synonym: "response to anoxic stress" EXACT [] +is_a: GO:0006950 ! response to stress +is_a: GO:0036293 ! response to decreased oxygen levels + +[Term] +id: GO:0034060 +name: cyanelle stroma +namespace: cellular_component +def: "The space enclosed by the double membrane of a cyanelle." [GOC:rph] +is_a: GO:0009532 ! plastid stroma +relationship: part_of GO:0009842 ! cyanelle + +[Term] +id: GO:0034061 +name: DNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group." [EC:2.7.7.7, GOC:mah] +synonym: "deoxynucleate polymerase activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleic acid polymerase activity" EXACT [EC:2.7.7.7] +synonym: "deoxyribonucleic polymerase activity" EXACT [EC:2.7.7.7] +synonym: "DNA nucleotidyltransferase activity" EXACT [EC:2.7.7.7] +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0071897 ! DNA biosynthetic process + +[Term] +id: GO:0034062 +name: 5'-3' RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end." [EC:2.7.7.6, GOC:mah, GOC:pf] +synonym: "C ribonucleic acid formation factors" RELATED [EC:2.7.7.6] +synonym: "C RNA formation factors" RELATED [EC:2.7.7.6] +synonym: "ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.6] +synonym: "ribonucleate polymerase activity" EXACT [EC:2.7.7.6] +synonym: "ribonucleic acid nucleotidyltransferase" BROAD [EC:2.7.7.6] +synonym: "ribonucleic acid polymerase activity" EXACT [EC:2.7.7.6] +synonym: "ribonucleic acid transcriptase activity" EXACT [EC:2.7.7.6] +synonym: "ribonucleic polymerase activity" EXACT [EC:2.7.7.6] +synonym: "ribonucleic transcriptase activity" EXACT [EC:2.7.7.6] +synonym: "RNA nucleotidyltransferase activity" EXACT [EC:2.7.7.6] +synonym: "RNA polymerase activity" BROAD [] +synonym: "RNA transcriptase activity" EXACT [EC:2.7.7.6] +synonym: "transcriptase" BROAD [EC:2.7.7.6] +xref: Reactome:R-HSA-5696807 "TRNT1 polymerizes CCA at the 3' end of pre-tRNA" +xref: Reactome:R-HSA-6786881 "TRNT1 polymerizes CCA at the 3' end of pre-tRNA" +is_a: GO:0097747 ! RNA polymerase activity + +[Term] +id: GO:0034063 +name: stress granule assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule." [GOC:mah, PMID:17392519] +synonym: "SG assembly" EXACT [PMID:19825938] +is_a: GO:0070925 ! organelle assembly + +[Term] +id: GO:0034064 +name: Tor2-Mei2-Ste11 complex +namespace: cellular_component +def: "A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast." [GOC:vw, PMID:17046992] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034066 +name: RIC1-RGP1 guanyl-nucleotide exchange factor complex +namespace: cellular_component +def: "A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi." [GOC:jh, GOC:mah, PMID:10990452] +synonym: "Ric1p-Rgp1p complex" RELATED [] +xref: IntAct:EBI-9517136 +is_a: GO:0032045 ! guanyl-nucleotide exchange factor complex +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0034067 +name: protein localization to Golgi apparatus +namespace: biological_process +alt_id: GO:0000042 +alt_id: GO:0072600 +def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah] +synonym: "establishment of protein localisation to Golgi" NARROW [GOC:mah] +synonym: "establishment of protein localization in Golgi" NARROW [] +synonym: "establishment of protein localization to Golgi" NARROW [] +synonym: "establishment of protein localization to Golgi apparatus" NARROW [GOC:mah] +synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah] +synonym: "protein localization in Golgi apparatus" EXACT [] +synonym: "protein targeting to Golgi" RELATED [] +synonym: "protein-Golgi targeting" RELATED [] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:26:36Z + +[Term] +id: GO:0034068 +name: aminoglycoside nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside." [GOC:cb] +synonym: "aminoglycoside adenylyltransferase activity" NARROW [] +synonym: "streptomycin adenylate synthetase activity" NARROW [EC:2.7.7.47] +synonym: "streptomycin adenyltransferase activity" NARROW [EC:2.7.7.47] +synonym: "streptomycin adenylylase activity" NARROW [EC:2.7.7.47] +synonym: "streptomycin adenylyltransferase activity" NARROW [EC:2.7.7.47] +synonym: "streptomycin-spectinomycin adenylyltransferase activity" NARROW [EC:2.7.7.47] +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0034069 +name: aminoglycoside N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside." [GOC:cb] +synonym: "kanamycin acetyltransferase activity" NARROW [] +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0034070 +name: aminoglycoside 1-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring." [GOC:cb] +is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity + +[Term] +id: GO:0034071 +name: aminoglycoside phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside." [GOC:cb, GOC:mah] +synonym: "aminoglycoside kinase activity" EXACT [] +xref: EC:2.7.1 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0034072 +name: squalene cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: squalene = triterpene." [GOC:cb, PMID:18033581] +is_a: GO:0009975 ! cyclase activity + +[Term] +id: GO:0034073 +name: tetrahymanol cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: squalene = tetrahymanol." [GOC:cb, PMID:18033581] +is_a: GO:0034072 ! squalene cyclase activity + +[Term] +id: GO:0034074 +name: marneral synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidosqualene = marneral." [GOC:cb, http://www.wiley-vch.de/contents/jc_2002/2006/z503420_s.pdf, PMID:16425307, PMID:18033581] +xref: MetaCyc:RXN-9664 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0034075 +name: arabidiol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol)." [GOC:cb, PMID:16774269, PMID:17474751] +xref: EC:4.2.1.124 +xref: MetaCyc:RXN-9684 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0034076 +name: cucurbitadienol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidosqualene = cucurbitadienol." [GOC:cb, PMID:18033581] +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0034077 +name: butanediol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [ISBN:0911910123, MetaCyc:BUTANEDIOL, MetaCyc:P125-PWY] +synonym: "butanediol metabolism" EXACT [] +synonym: "butylene glycol metabolic process" EXACT [] +synonym: "butylene glycol metabolism" EXACT [] +is_a: GO:0042844 ! glycol metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0034078 +name: butanediol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:125-PWY, MetaCyc:BUTANEDIOL] +synonym: "butanediol breakdown" EXACT [] +synonym: "butanediol catabolism" EXACT [] +synonym: "butanediol degradation" EXACT [] +synonym: "butanediol utilization" RELATED [] +synonym: "butylene glycol catabolic process" EXACT [] +synonym: "butylene glycol catabolism" EXACT [] +is_a: GO:0034077 ! butanediol metabolic process +is_a: GO:0042846 ! glycol catabolic process + +[Term] +id: GO:0034079 +name: butanediol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:125-PWY, MetaCyc:BUTANEDIOL] +synonym: "butanediol anabolism" EXACT [] +synonym: "butanediol biosynthesis" EXACT [] +synonym: "butanediol formation" EXACT [] +synonym: "butanediol synthesis" EXACT [] +synonym: "butylene glycol biosynthesis" EXACT [] +synonym: "butylene glycol biosynthetic process" EXACT [] +xref: MetaCyc:P125-PWY +is_a: GO:0034077 ! butanediol metabolic process +is_a: GO:0042845 ! glycol biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0034080 +name: CENP-A containing nucleosome assembly +namespace: biological_process +alt_id: GO:0034509 +def: "The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres." [GOC:mah, GOC:vw, PMID:18158900, PMID:19217403] +synonym: "CenH3-containing nucleosome assembly at centromere" RELATED [] +synonym: "CENP-A containing nucleosome assembly at centromere" EXACT [GOC:vw] +synonym: "CENP-A deposition" RELATED [GOC:vw] +synonym: "CENP-A loading" RELATED [GOC:vw] +synonym: "centromere specific nucleosome exchange" RELATED [GOC:mah] +synonym: "centromere-specific histone exchange" EXACT [GOC:mah, GOC:vw] +synonym: "centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:mah] +synonym: "DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:mah] +is_a: GO:0006336 ! DNA replication-independent nucleosome assembly +is_a: GO:0031055 ! chromatin remodeling at centromere +is_a: GO:0043486 ! histone exchange +relationship: has_part GO:0061644 ! protein localization to CENP-A containing chromatin +relationship: part_of GO:0034508 ! centromere complex assembly +relationship: part_of GO:0061641 ! CENP-A containing chromatin organization + +[Term] +id: GO:0034081 +name: polyketide synthase complex +namespace: cellular_component +def: "A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones." [GOC:mah, PMID:12636085] +synonym: "PKS" RELATED [] +synonym: "PKS complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034082 +name: type II polyketide synthase complex +namespace: cellular_component +def: "A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction." [GOC:cb, GOC:mah, PMID:12636085] +synonym: "type II PKS" EXACT [] +synonym: "type II PKS complex" EXACT [] +synonym: "type II polyketide synthase" EXACT [] +is_a: GO:0034081 ! polyketide synthase complex + +[Term] +id: GO:0034083 +name: type III polyketide synthase complex +namespace: cellular_component +def: "A polyketide synthase complex that consists of two identical ketosynthase polypeptides." [GOC:cb, PMID:12636085] +synonym: "type III PKS" EXACT [] +synonym: "type III PKS complex" EXACT [] +synonym: "type III polyketide synthase" EXACT [] +is_a: GO:0034081 ! polyketide synthase complex + +[Term] +id: GO:0034084 +name: steryl deacetylase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol." [GOC:rb, PMID:18034159] +synonym: "sterol deacetylase activity" EXACT [] +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0034085 +name: establishment of sister chromatid cohesion +namespace: biological_process +def: "The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase." [GOC:jh, GOC:mah, PMID:14623866] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007062 ! sister chromatid cohesion + +[Term] +id: GO:0034086 +name: maintenance of sister chromatid cohesion +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate." [GOC:mah, PMID:14623866] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007062 ! sister chromatid cohesion + +[Term] +id: GO:0034087 +name: establishment of mitotic sister chromatid cohesion +namespace: biological_process +def: "The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle." [GOC:mah] +is_a: GO:0034085 ! establishment of sister chromatid cohesion +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0034085 ! establishment of sister chromatid cohesion +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0007064 ! mitotic sister chromatid cohesion + +[Term] +id: GO:0034088 +name: maintenance of mitotic sister chromatid cohesion +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle." [GOC:mah] +synonym: "mitotic cohesion stability" RELATED [] +is_a: GO:0034086 ! maintenance of sister chromatid cohesion +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007064 ! mitotic sister chromatid cohesion + +[Term] +id: GO:0034089 +name: establishment of meiotic sister chromatid cohesion +namespace: biological_process +def: "The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle." [GOC:mah] +is_a: GO:0034085 ! establishment of sister chromatid cohesion +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0051177 ! meiotic sister chromatid cohesion + +[Term] +id: GO:0034090 +name: maintenance of meiotic sister chromatid cohesion +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:mah] +is_a: GO:0034086 ! maintenance of sister chromatid cohesion +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0051177 ! meiotic sister chromatid cohesion + +[Term] +id: GO:0034091 +name: regulation of maintenance of sister chromatid cohesion +namespace: biological_process +def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034086 ! maintenance of sister chromatid cohesion +relationship: regulates GO:0034086 ! maintenance of sister chromatid cohesion + +[Term] +id: GO:0034092 +name: negative regulation of maintenance of sister chromatid cohesion +namespace: biological_process +def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] +is_a: GO:0034091 ! regulation of maintenance of sister chromatid cohesion +is_a: GO:0045875 ! negative regulation of sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034086 ! maintenance of sister chromatid cohesion +relationship: negatively_regulates GO:0034086 ! maintenance of sister chromatid cohesion + +[Term] +id: GO:0034093 +name: positive regulation of maintenance of sister chromatid cohesion +namespace: biological_process +def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] +is_a: GO:0034091 ! regulation of maintenance of sister chromatid cohesion +is_a: GO:0045876 ! positive regulation of sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034086 ! maintenance of sister chromatid cohesion +relationship: positively_regulates GO:0034086 ! maintenance of sister chromatid cohesion + +[Term] +id: GO:0034094 +name: regulation of maintenance of meiotic sister chromatid cohesion +namespace: biological_process +def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0034091 ! regulation of maintenance of sister chromatid cohesion +is_a: GO:0040020 ! regulation of meiotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion +relationship: regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion + +[Term] +id: GO:0034095 +name: negative regulation of maintenance of meiotic sister chromatid cohesion +namespace: biological_process +def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0034092 ! negative regulation of maintenance of sister chromatid cohesion +is_a: GO:0034094 ! regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:0045835 ! negative regulation of meiotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion +relationship: negatively_regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion + +[Term] +id: GO:0034096 +name: positive regulation of maintenance of meiotic sister chromatid cohesion +namespace: biological_process +def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0034093 ! positive regulation of maintenance of sister chromatid cohesion +is_a: GO:0034094 ! regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:0045836 ! positive regulation of meiotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion +relationship: positively_regulates GO:0034090 ! maintenance of meiotic sister chromatid cohesion + +[Term] +id: GO:0034097 +name: response to cytokine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus." [GOC:sl] +synonym: "response to cytokine stimulus" EXACT [GOC:dos] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0034098 +name: VCP-NPL4-UFD1 AAA ATPase complex +namespace: cellular_component +def: "A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry)." [PMID:11813000, PMID:16179952] +synonym: "Cdc48p-Npl4p-Ufd1p AAA ATPase complex" NARROW [] +synonym: "p97-Ufd1-Npl4 complex" EXACT [PMID:12847084] +is_a: GO:0098796 ! membrane protein complex +relationship: has_part GO:0036501 ! UFD1-NPL4 complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0034099 +name: luminal surveillance complex +namespace: cellular_component +def: "A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins." [PMID:16873065] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005788 ! endoplasmic reticulum lumen + +[Term] +id: GO:0034101 +name: erythrocyte homeostasis +namespace: biological_process +def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397] +synonym: "RBC homeostasis" EXACT [CL:0000232] +synonym: "red blood cell homeostasis" EXACT [CL:0000232] +is_a: GO:0002262 ! myeloid cell homeostasis + +[Term] +id: GO:0034102 +name: erythrocyte clearance +namespace: biological_process +def: "The selective elimination of erythrocytes from the body by autoregulatory mechanisms." [GOC:add, PMID:12905029, PMID:14754397] +comment: Note that this term is intended for annotation of self-gene products that lead to elimination of erythrocytes without the involvement of a symbiont. +synonym: "neocytolysis" NARROW [PMID:14754397] +synonym: "RBC clearance" EXACT [CL:0000232] +synonym: "red blood cell clearance" EXACT [CL:0000232] +is_a: GO:0048771 ! tissue remodeling +relationship: part_of GO:0034101 ! erythrocyte homeostasis + +[Term] +id: GO:0034103 +name: regulation of tissue remodeling +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of tissue remodeling." [GOC:add] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048771 ! tissue remodeling +relationship: regulates GO:0048771 ! tissue remodeling + +[Term] +id: GO:0034104 +name: negative regulation of tissue remodeling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling." [GOC:add] +is_a: GO:0034103 ! regulation of tissue remodeling +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048771 ! tissue remodeling +relationship: negatively_regulates GO:0048771 ! tissue remodeling + +[Term] +id: GO:0034105 +name: positive regulation of tissue remodeling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of tissue remodeling." [GOC:add] +is_a: GO:0034103 ! regulation of tissue remodeling +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048771 ! tissue remodeling +relationship: positively_regulates GO:0048771 ! tissue remodeling + +[Term] +id: GO:0034106 +name: regulation of erythrocyte clearance +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of erythrocyte clearance." [GOC:add, PMID:12905029, PMID:14754397] +synonym: "regulation of neocytolysis" NARROW [PMID:14754397] +synonym: "regulation of RBC clearance" EXACT [CL:0000232] +synonym: "regulation of red blood cell clearance" EXACT [CL:0000232] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0034103 ! regulation of tissue remodeling +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034102 ! erythrocyte clearance +relationship: regulates GO:0034102 ! erythrocyte clearance + +[Term] +id: GO:0034107 +name: negative regulation of erythrocyte clearance +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance." [GOC:add, PMID:12905029, PMID:14754397] +synonym: "negative regulation of neocytolysis" NARROW [PMID:14754397] +synonym: "negative regulation of RBC clearance" EXACT [CL:0000232] +synonym: "negative regulation of red blood cell clearance" EXACT [CL:0000232] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0034104 ! negative regulation of tissue remodeling +is_a: GO:0034106 ! regulation of erythrocyte clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034102 ! erythrocyte clearance +relationship: negatively_regulates GO:0034102 ! erythrocyte clearance + +[Term] +id: GO:0034108 +name: positive regulation of erythrocyte clearance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance." [GOC:add, PMID:12905029, PMID:14754397] +synonym: "positive regulation of neocytolysis" NARROW [PMID:14754397] +synonym: "positive regulation of RBC clearance" EXACT [CL:0000232] +synonym: "positive regulation of red blood cell clearance" EXACT [CL:0000232] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0034105 ! positive regulation of tissue remodeling +is_a: GO:0034106 ! regulation of erythrocyte clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034102 ! erythrocyte clearance +relationship: positively_regulates GO:0034102 ! erythrocyte clearance + +[Term] +id: GO:0034109 +name: homotypic cell-cell adhesion +namespace: biological_process +def: "The attachment of a cell to a second cell of the identical type via adhesion molecules." [GOC:add] +comment: Note that this term is not synonymous with 'homophilic cell adhesion ; GO:0007156'; the process may occur by homophilic or heterophilic mechanisms. +is_a: GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0034110 +name: regulation of homotypic cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034109 ! homotypic cell-cell adhesion +relationship: regulates GO:0034109 ! homotypic cell-cell adhesion + +[Term] +id: GO:0034111 +name: negative regulation of homotypic cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0034110 ! regulation of homotypic cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034109 ! homotypic cell-cell adhesion +relationship: negatively_regulates GO:0034109 ! homotypic cell-cell adhesion + +[Term] +id: GO:0034112 +name: positive regulation of homotypic cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0034110 ! regulation of homotypic cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034109 ! homotypic cell-cell adhesion +relationship: positively_regulates GO:0034109 ! homotypic cell-cell adhesion + +[Term] +id: GO:0034113 +name: heterotypic cell-cell adhesion +namespace: biological_process +def: "The attachment of a cell to a cell of a different type via adhesion molecules." [GOC:add] +comment: Note that this term is not synonymous with 'heterophilic cell adhesion ; GO:0007157'; the process may occur by homophilic or heterophilic mechanisms. +is_a: GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0034114 +name: regulation of heterotypic cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034113 ! heterotypic cell-cell adhesion +relationship: regulates GO:0034113 ! heterotypic cell-cell adhesion + +[Term] +id: GO:0034115 +name: negative regulation of heterotypic cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0034114 ! regulation of heterotypic cell-cell adhesion +is_a: GO:0070587 ! regulation of cell-cell adhesion involved in gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034113 ! heterotypic cell-cell adhesion +relationship: negatively_regulates GO:0034113 ! heterotypic cell-cell adhesion + +[Term] +id: GO:0034116 +name: positive regulation of heterotypic cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0034114 ! regulation of heterotypic cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034113 ! heterotypic cell-cell adhesion +relationship: positively_regulates GO:0034113 ! heterotypic cell-cell adhesion + +[Term] +id: GO:0034117 +name: erythrocyte aggregation +namespace: biological_process +def: "The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules." [GOC:add, PMID:14631543] +synonym: "RBC aggregation" EXACT [CL:0000232] +synonym: "red blood cell aggregation" EXACT [CL:0000232] +is_a: GO:0034109 ! homotypic cell-cell adhesion + +[Term] +id: GO:0034118 +name: regulation of erythrocyte aggregation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] +synonym: "regulation of RBC aggregation" EXACT [CL:0000232] +synonym: "regulation of red blood cell aggregation" EXACT [CL:0000232] +is_a: GO:0034110 ! regulation of homotypic cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034117 ! erythrocyte aggregation +relationship: regulates GO:0034117 ! erythrocyte aggregation + +[Term] +id: GO:0034119 +name: negative regulation of erythrocyte aggregation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] +synonym: "negative regulation of RBC aggregation" EXACT [CL:0000232] +synonym: "negative regulation of red blood cell aggregation" EXACT [CL:0000232] +is_a: GO:0034111 ! negative regulation of homotypic cell-cell adhesion +is_a: GO:0034118 ! regulation of erythrocyte aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034117 ! erythrocyte aggregation +relationship: negatively_regulates GO:0034117 ! erythrocyte aggregation + +[Term] +id: GO:0034120 +name: positive regulation of erythrocyte aggregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] +synonym: "positive regulation of RBC aggregation" EXACT [CL:0000232] +synonym: "positive regulation of red blood cell aggregation" EXACT [CL:0000232] +is_a: GO:0034112 ! positive regulation of homotypic cell-cell adhesion +is_a: GO:0034118 ! regulation of erythrocyte aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034117 ! erythrocyte aggregation +relationship: positively_regulates GO:0034117 ! erythrocyte aggregation + +[Term] +id: GO:0034121 +name: regulation of toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor signalling pathway" EXACT [] +is_a: GO:0062207 ! regulation of pattern recognition receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002224 ! toll-like receptor signaling pathway +relationship: regulates GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034122 +name: negative regulation of toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002224 ! toll-like receptor signaling pathway +relationship: negatively_regulates GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034123 +name: positive regulation of toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +is_a: GO:0062208 ! positive regulation of pattern recognition receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002224 ! toll-like receptor signaling pathway +relationship: positively_regulates GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034124 +name: regulation of MyD88-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation ofMyD88-dependent TLR signaling pathway" EXACT [] +synonym: "regulation ofMyD88-dependent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway +relationship: regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway + +[Term] +id: GO:0034125 +name: negative regulation of MyD88-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of MyD88-dependent TLR signaling pathway" EXACT [] +synonym: "negative regulation of MyD88-dependent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034124 ! regulation of MyD88-dependent toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway +relationship: negatively_regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway + +[Term] +id: GO:0034126 +name: positive regulation of MyD88-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of MyD88-dependent TLR signaling pathway" EXACT [] +synonym: "positive regulation of MyD88-dependent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034124 ! regulation of MyD88-dependent toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway +relationship: positively_regulates GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway + +[Term] +id: GO:0034127 +name: regulation of MyD88-independent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation ofMyD88-independent TLR signaling pathway" EXACT [] +synonym: "regulation ofMyD88-independent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway +relationship: regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway + +[Term] +id: GO:0034128 +name: negative regulation of MyD88-independent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of MyD88-independent TLR signaling pathway" EXACT [] +synonym: "negative regulation of MyD88-independent toll-like receptor signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034127 ! regulation of MyD88-independent toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway +relationship: negatively_regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway + +[Term] +id: GO:0034129 +name: positive regulation of MyD88-independent toll-like receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of MyD88-independent TLR signaling pathway" EXACT [] +synonym: "positive regulation of MyD88-independent toll-like receptor" EXACT [] +synonym: "positive regulation of MyD88-independent toll-like receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034127 ! regulation of MyD88-independent toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway +relationship: positively_regulates GO:0002756 ! MyD88-independent toll-like receptor signaling pathway + +[Term] +id: GO:0034130 +name: toll-like receptor 1 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 1." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR1 signaling pathway" EXACT [] +synonym: "toll-like receptor 1 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034131 +name: regulation of toll-like receptor 1 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR1 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 1 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034130 ! toll-like receptor 1 signaling pathway +relationship: regulates GO:0034130 ! toll-like receptor 1 signaling pathway + +[Term] +id: GO:0034132 +name: negative regulation of toll-like receptor 1 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR1 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 1 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034131 ! regulation of toll-like receptor 1 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034130 ! toll-like receptor 1 signaling pathway +relationship: negatively_regulates GO:0034130 ! toll-like receptor 1 signaling pathway + +[Term] +id: GO:0034133 +name: positive regulation of toll-like receptor 1 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR1 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 1 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034131 ! regulation of toll-like receptor 1 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034130 ! toll-like receptor 1 signaling pathway +relationship: positively_regulates GO:0034130 ! toll-like receptor 1 signaling pathway + +[Term] +id: GO:0034134 +name: toll-like receptor 2 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 2." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR2 signaling pathway" EXACT [] +synonym: "toll-like receptor 2 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034135 +name: regulation of toll-like receptor 2 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR2 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 2 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034134 ! toll-like receptor 2 signaling pathway +relationship: regulates GO:0034134 ! toll-like receptor 2 signaling pathway + +[Term] +id: GO:0034136 +name: negative regulation of toll-like receptor 2 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR2 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 2 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034135 ! regulation of toll-like receptor 2 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034134 ! toll-like receptor 2 signaling pathway +relationship: negatively_regulates GO:0034134 ! toll-like receptor 2 signaling pathway + +[Term] +id: GO:0034137 +name: positive regulation of toll-like receptor 2 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR2 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 2 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034135 ! regulation of toll-like receptor 2 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034134 ! toll-like receptor 2 signaling pathway +relationship: positively_regulates GO:0034134 ! toll-like receptor 2 signaling pathway + +[Term] +id: GO:0034138 +name: toll-like receptor 3 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 3." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR3 signaling pathway" EXACT [] +synonym: "toll-like receptor 3 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034139 +name: regulation of toll-like receptor 3 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR3 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 3 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034138 ! toll-like receptor 3 signaling pathway +relationship: regulates GO:0034138 ! toll-like receptor 3 signaling pathway + +[Term] +id: GO:0034140 +name: negative regulation of toll-like receptor 3 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR3 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 3 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034139 ! regulation of toll-like receptor 3 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034138 ! toll-like receptor 3 signaling pathway +relationship: negatively_regulates GO:0034138 ! toll-like receptor 3 signaling pathway + +[Term] +id: GO:0034141 +name: positive regulation of toll-like receptor 3 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR3 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 3 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034139 ! regulation of toll-like receptor 3 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034138 ! toll-like receptor 3 signaling pathway +relationship: positively_regulates GO:0034138 ! toll-like receptor 3 signaling pathway + +[Term] +id: GO:0034142 +name: toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 4." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR4 signaling pathway" EXACT [] +synonym: "toll-like receptor 4 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034143 +name: regulation of toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR4 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 4 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034142 ! toll-like receptor 4 signaling pathway +relationship: regulates GO:0034142 ! toll-like receptor 4 signaling pathway + +[Term] +id: GO:0034144 +name: negative regulation of toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR4 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 4 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034143 ! regulation of toll-like receptor 4 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034142 ! toll-like receptor 4 signaling pathway +relationship: negatively_regulates GO:0034142 ! toll-like receptor 4 signaling pathway + +[Term] +id: GO:0034145 +name: positive regulation of toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR4 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 4 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034143 ! regulation of toll-like receptor 4 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034142 ! toll-like receptor 4 signaling pathway +relationship: positively_regulates GO:0034142 ! toll-like receptor 4 signaling pathway + +[Term] +id: GO:0034146 +name: toll-like receptor 5 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 5." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR5 signaling pathway" EXACT [] +synonym: "toll-like receptor 5 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034147 +name: regulation of toll-like receptor 5 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR5 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 5 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034146 ! toll-like receptor 5 signaling pathway +relationship: regulates GO:0034146 ! toll-like receptor 5 signaling pathway + +[Term] +id: GO:0034148 +name: negative regulation of toll-like receptor 5 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR5 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 5 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034147 ! regulation of toll-like receptor 5 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034146 ! toll-like receptor 5 signaling pathway +relationship: negatively_regulates GO:0034146 ! toll-like receptor 5 signaling pathway + +[Term] +id: GO:0034149 +name: positive regulation of toll-like receptor 5 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR5 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 5 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034147 ! regulation of toll-like receptor 5 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034146 ! toll-like receptor 5 signaling pathway +relationship: positively_regulates GO:0034146 ! toll-like receptor 5 signaling pathway + +[Term] +id: GO:0034150 +name: toll-like receptor 6 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 6." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR6 signaling pathway" EXACT [] +synonym: "toll-like receptor 6 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034151 +name: regulation of toll-like receptor 6 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR6 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 6 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034150 ! toll-like receptor 6 signaling pathway +relationship: regulates GO:0034150 ! toll-like receptor 6 signaling pathway + +[Term] +id: GO:0034152 +name: negative regulation of toll-like receptor 6 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR6 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 6 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034151 ! regulation of toll-like receptor 6 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034150 ! toll-like receptor 6 signaling pathway +relationship: negatively_regulates GO:0034150 ! toll-like receptor 6 signaling pathway + +[Term] +id: GO:0034153 +name: positive regulation of toll-like receptor 6 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR6 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 6 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034151 ! regulation of toll-like receptor 6 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034150 ! toll-like receptor 6 signaling pathway +relationship: positively_regulates GO:0034150 ! toll-like receptor 6 signaling pathway + +[Term] +id: GO:0034154 +name: toll-like receptor 7 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 7." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR7 signaling pathway" EXACT [] +synonym: "toll-like receptor 7 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034155 +name: regulation of toll-like receptor 7 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR7 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 7 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034154 ! toll-like receptor 7 signaling pathway +relationship: regulates GO:0034154 ! toll-like receptor 7 signaling pathway + +[Term] +id: GO:0034156 +name: negative regulation of toll-like receptor 7 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR7 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 7 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034155 ! regulation of toll-like receptor 7 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034154 ! toll-like receptor 7 signaling pathway +relationship: negatively_regulates GO:0034154 ! toll-like receptor 7 signaling pathway + +[Term] +id: GO:0034157 +name: positive regulation of toll-like receptor 7 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR7 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 7 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034155 ! regulation of toll-like receptor 7 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034154 ! toll-like receptor 7 signaling pathway +relationship: positively_regulates GO:0034154 ! toll-like receptor 7 signaling pathway + +[Term] +id: GO:0034158 +name: toll-like receptor 8 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 8." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR8 signaling pathway" EXACT [] +synonym: "toll-like receptor 8 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034159 +name: regulation of toll-like receptor 8 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR8 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 8 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034158 ! toll-like receptor 8 signaling pathway +relationship: regulates GO:0034158 ! toll-like receptor 8 signaling pathway + +[Term] +id: GO:0034160 +name: negative regulation of toll-like receptor 8 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR8 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 8 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034159 ! regulation of toll-like receptor 8 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034158 ! toll-like receptor 8 signaling pathway +relationship: negatively_regulates GO:0034158 ! toll-like receptor 8 signaling pathway + +[Term] +id: GO:0034161 +name: positive regulation of toll-like receptor 8 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR8 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 8 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034159 ! regulation of toll-like receptor 8 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034158 ! toll-like receptor 8 signaling pathway +relationship: positively_regulates GO:0034158 ! toll-like receptor 8 signaling pathway + +[Term] +id: GO:0034162 +name: toll-like receptor 9 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 9." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR9 signaling pathway" EXACT [] +synonym: "toll-like receptor 9 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034163 +name: regulation of toll-like receptor 9 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR9 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 9 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034162 ! toll-like receptor 9 signaling pathway +relationship: regulates GO:0034162 ! toll-like receptor 9 signaling pathway + +[Term] +id: GO:0034164 +name: negative regulation of toll-like receptor 9 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR9 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 9 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034163 ! regulation of toll-like receptor 9 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034162 ! toll-like receptor 9 signaling pathway +relationship: negatively_regulates GO:0034162 ! toll-like receptor 9 signaling pathway + +[Term] +id: GO:0034165 +name: positive regulation of toll-like receptor 9 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR9 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 9 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034163 ! regulation of toll-like receptor 9 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034162 ! toll-like receptor 9 signaling pathway +relationship: positively_regulates GO:0034162 ! toll-like receptor 9 signaling pathway + +[Term] +id: GO:0034166 +name: toll-like receptor 10 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 10." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR10 signaling pathway" EXACT [] +synonym: "toll-like receptor 10 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034167 +name: regulation of toll-like receptor 10 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR10 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 10 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034166 ! toll-like receptor 10 signaling pathway +relationship: regulates GO:0034166 ! toll-like receptor 10 signaling pathway + +[Term] +id: GO:0034168 +name: negative regulation of toll-like receptor 10 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR10 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 10 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034167 ! regulation of toll-like receptor 10 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034166 ! toll-like receptor 10 signaling pathway +relationship: negatively_regulates GO:0034166 ! toll-like receptor 10 signaling pathway + +[Term] +id: GO:0034169 +name: positive regulation of toll-like receptor 10 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR10 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 10 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034167 ! regulation of toll-like receptor 10 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034166 ! toll-like receptor 10 signaling pathway +relationship: positively_regulates GO:0034166 ! toll-like receptor 10 signaling pathway + +[Term] +id: GO:0034170 +name: toll-like receptor 11 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 11." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR11 signaling pathway" EXACT [] +synonym: "toll-like receptor 11 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034171 +name: regulation of toll-like receptor 11 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR11 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 11 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034170 ! toll-like receptor 11 signaling pathway +relationship: regulates GO:0034170 ! toll-like receptor 11 signaling pathway + +[Term] +id: GO:0034172 +name: negative regulation of toll-like receptor 11 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR11 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 11 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034171 ! regulation of toll-like receptor 11 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034170 ! toll-like receptor 11 signaling pathway +relationship: negatively_regulates GO:0034170 ! toll-like receptor 11 signaling pathway + +[Term] +id: GO:0034173 +name: positive regulation of toll-like receptor 11 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR11 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 11 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034171 ! regulation of toll-like receptor 11 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034170 ! toll-like receptor 11 signaling pathway +relationship: positively_regulates GO:0034170 ! toll-like receptor 11 signaling pathway + +[Term] +id: GO:0034174 +name: toll-like receptor 12 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 12." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR12 signaling pathway" EXACT [] +synonym: "toll-like receptor 12 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034175 +name: regulation of toll-like receptor 12 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR12 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 12 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034174 ! toll-like receptor 12 signaling pathway +relationship: regulates GO:0034174 ! toll-like receptor 12 signaling pathway + +[Term] +id: GO:0034176 +name: negative regulation of toll-like receptor 12 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR12 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 12 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034175 ! regulation of toll-like receptor 12 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034174 ! toll-like receptor 12 signaling pathway +relationship: negatively_regulates GO:0034174 ! toll-like receptor 12 signaling pathway + +[Term] +id: GO:0034177 +name: positive regulation of toll-like receptor 12 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR12 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 12 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034175 ! regulation of toll-like receptor 12 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034174 ! toll-like receptor 12 signaling pathway +relationship: positively_regulates GO:0034174 ! toll-like receptor 12 signaling pathway + +[Term] +id: GO:0034178 +name: toll-like receptor 13 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 13." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "TLR13 signaling pathway" EXACT [] +synonym: "toll-like receptor 13 signalling pathway" EXACT [] +is_a: GO:0002224 ! toll-like receptor signaling pathway + +[Term] +id: GO:0034179 +name: regulation of toll-like receptor 13 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "regulation of TLR13 signaling pathway" EXACT [] +synonym: "regulation of toll-like receptor 13 signalling pathway" EXACT [] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034178 ! toll-like receptor 13 signaling pathway +relationship: regulates GO:0034178 ! toll-like receptor 13 signaling pathway + +[Term] +id: GO:0034180 +name: negative regulation of toll-like receptor 13 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "negative regulation of TLR13 signaling pathway" EXACT [] +synonym: "negative regulation of toll-like receptor 13 signalling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0034179 ! regulation of toll-like receptor 13 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034178 ! toll-like receptor 13 signaling pathway +relationship: negatively_regulates GO:0034178 ! toll-like receptor 13 signaling pathway + +[Term] +id: GO:0034181 +name: positive regulation of toll-like receptor 13 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] +synonym: "positive regulation of TLR13 signaling pathway" EXACT [] +synonym: "positive regulation of toll-like receptor 13 signalling pathway" EXACT [] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:0034179 ! regulation of toll-like receptor 13 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034178 ! toll-like receptor 13 signaling pathway +relationship: positively_regulates GO:0034178 ! toll-like receptor 13 signaling pathway + +[Term] +id: GO:0034182 +name: regulation of maintenance of mitotic sister chromatid cohesion +namespace: biological_process +def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0034091 ! regulation of maintenance of sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion + +[Term] +id: GO:0034183 +name: negative regulation of maintenance of mitotic sister chromatid cohesion +namespace: biological_process +def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:0034092 ! negative regulation of maintenance of sister chromatid cohesion +is_a: GO:0034182 ! regulation of maintenance of mitotic sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: negatively_regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion + +[Term] +id: GO:0034184 +name: positive regulation of maintenance of mitotic sister chromatid cohesion +namespace: biological_process +def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] +is_a: GO:0034093 ! positive regulation of maintenance of sister chromatid cohesion +is_a: GO:0034182 ! regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: positively_regulates GO:0034088 ! maintenance of mitotic sister chromatid cohesion + +[Term] +id: GO:0034185 +name: apolipoprotein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex." [GOC:BHF, GOC:rl] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0034186 +name: apolipoprotein A-I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with apolipoprotein A-I." [GOC:BHF, GOC:rl] +is_a: GO:0034185 ! apolipoprotein binding + +[Term] +id: GO:0034187 +name: obsolete apolipoprotein E binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with apolipoprotein E." [GOC:BHF, GOC:rl] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "apolipoprotein E binding" EXACT [] +is_obsolete: true +replaced_by: GO:0034185 + +[Term] +id: GO:0034188 +name: apolipoprotein A-I receptor activity +namespace: molecular_function +def: "Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:BHF, GOC:rl, GOC:signaling, PMID:16443932] +is_a: GO:0004888 ! transmembrane signaling receptor activity +is_a: GO:0030226 ! apolipoprotein receptor activity +relationship: has_part GO:0034186 ! apolipoprotein A-I binding +relationship: part_of GO:0038027 ! apolipoprotein A-I-mediated signaling pathway + +[Term] +id: GO:0034189 +name: very-low-density lipoprotein particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm." [GOC:BHF, GOC:mah] +synonym: "very-low-density lipoprotein binding" EXACT [GOC:bf, GOC:dph] +synonym: "VLDL binding" EXACT [] +is_a: GO:0005515 ! protein binding +is_a: GO:0071813 ! lipoprotein particle binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0034190 +name: apolipoprotein receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an apolipoprotein receptor." [GOC:BHF, GOC:rl] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0034191 +name: apolipoprotein A-I receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an apolipoprotein A-I receptor." [GOC:BHF, GOC:rl] +comment: Note that this term is to be used only to annotate gene products that bind to lipid-free APOA1. For receptors that bind lipid-associated apolipoproteins (plasma lipoprotein particles), consider annotating to 'lipoprotein receptor activity ; GO:0030228' or its child terms. +is_a: GO:0034190 ! apolipoprotein receptor binding + +[Term] +id: GO:0034192 +name: D-galactonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid." [GOC:mah] +synonym: "D-galactonate metabolism" EXACT [] +is_a: GO:0019583 ! galactonate metabolic process + +[Term] +id: GO:0034193 +name: L-galactonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid." [GOC:mah] +synonym: "L-galactonate metabolism" EXACT [] +is_a: GO:0019583 ! galactonate metabolic process + +[Term] +id: GO:0034194 +name: D-galactonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid." [GOC:ai, GOC:mah] +synonym: "D-galactonate breakdown" EXACT [] +synonym: "D-galactonate catabolism" EXACT [] +synonym: "D-galactonate degradation" EXACT [] +xref: MetaCyc:GALACTCAT-PWY +is_a: GO:0019584 ! galactonate catabolic process +is_a: GO:0034192 ! D-galactonate metabolic process + +[Term] +id: GO:0034195 +name: L-galactonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid." [GOC:ai, GOC:mah] +synonym: "L-galactonate breakdown" EXACT [] +synonym: "L-galactonate catabolism" EXACT [] +synonym: "L-galactonate degradation" EXACT [] +xref: MetaCyc:GALACTCAT-PWY +is_a: GO:0019584 ! galactonate catabolic process +is_a: GO:0034193 ! L-galactonate metabolic process + +[Term] +id: GO:0034196 +name: acylglycerol transport +namespace: biological_process +def: "The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids." [GOC:BHF, GOC:rl] +synonym: "glyceride transport" EXACT [] +is_a: GO:0006869 ! lipid transport + +[Term] +id: GO:0034197 +name: triglyceride transport +namespace: biological_process +def: "The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins." [GOC:BHF, GOC:rl] +synonym: "triacylglycerol transport" EXACT [] +is_a: GO:0034196 ! acylglycerol transport + +[Term] +id: GO:0034198 +name: cellular response to amino acid starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids." [GOC:ecd] +synonym: "GAAC response" NARROW [PMID:29596413] +synonym: "general amino acid control response" NARROW [PMID:29596413] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:1990928 ! response to amino acid starvation + +[Term] +id: GO:0034199 +name: activation of protein kinase A activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme protein kinase A." [GOC:pde] +synonym: "protein kinase A activation" EXACT [] +is_a: GO:0032147 ! activation of protein kinase activity + +[Term] +id: GO:0034200 +name: D,D-heptose 1,7-bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate." [MetaCyc:RXN0-4361, PMID:11279237] +xref: MetaCyc:RXN0-4361 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0034201 +name: response to oleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus." [GOC:lp] +synonym: "response to oleate" EXACT [GOC:mah] +is_a: GO:0070542 ! response to fatty acid + +[Term] +id: GO:0034202 +name: glycolipid floppase activity +namespace: molecular_function +def: "Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:krc, PMID:11807558] +synonym: "ATP-dependent intramembrane glycolipid transporter activity" BROAD [] +synonym: "ATPase-coupled intramembrane glycolipid transporter activity" BROAD [] +synonym: "glycolipid floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "glycolipid-translocating activity" BROAD [] +xref: Reactome:R-HSA-446212 "Flipping of the N-glycan precursor to inside the ER" +xref: Reactome:R-HSA-4570573 "Defective RFT1 does not flip the N-glycan precursor" +is_a: GO:0140328 ! floppase activity +relationship: part_of GO:0034203 ! glycolipid translocation + +[Term] +id: GO:0034203 +name: glycolipid translocation +namespace: biological_process +def: "The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:go_curators, PMID:11807558] +is_a: GO:0034204 ! lipid translocation +is_a: GO:0046836 ! glycolipid transport + +[Term] +id: GO:0034204 +name: lipid translocation +namespace: biological_process +def: "The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:mah] +synonym: "intramembrane lipid transfer" EXACT [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0097035 ! regulation of membrane lipid distribution + +[Term] +id: GO:0034205 +name: amyloid-beta formation +namespace: biological_process +def: "The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP)." [GOC:mah] +comment: Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because amyloid-beta can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the amyloid-beta polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form amyloid-beta. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000). +synonym: "beta-amyloid formation" EXACT [] +synonym: "beta-amyloid polypeptide formation from amyloid precursor protein" EXACT [] +synonym: "beta-amyloid polypeptide formation from APP" EXACT [] +is_a: GO:0042987 ! amyloid precursor protein catabolic process +is_a: GO:0050435 ! amyloid-beta metabolic process + +[Term] +id: GO:0034206 +name: enhanceosome +namespace: cellular_component +def: "A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation." [PMID:11250145, PMID:17574024] +xref: Wikipedia:Enhanceosome +is_a: GO:0032993 ! protein-DNA complex + +[Term] +id: GO:0034207 +name: steroid acetylation +namespace: biological_process +def: "The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:mah] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0030258 ! lipid modification + +[Term] +id: GO:0034208 +name: steroid deacetylation +namespace: biological_process +def: "The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:mah] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0030258 ! lipid modification + +[Term] +id: GO:0034209 +name: sterol acetylation +namespace: biological_process +def: "The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:rb, PMID:18034159] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:0034207 ! steroid acetylation + +[Term] +id: GO:0034210 +name: sterol deacetylation +namespace: biological_process +def: "The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:rb, PMID:18034159] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:0034208 ! steroid deacetylation + +[Term] +id: GO:0034211 +name: GTP-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP." [GOC:ecd, PMID:17200152] +is_a: GO:0004674 ! protein serine/threonine kinase activity + +[Term] +id: GO:0034212 +name: peptide N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide." [GOC:mah] +xref: Reactome:R-HSA-3371554 "HSF1 acetylation at Lys80" +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0034213 +name: quinolinate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid." [GOC:mah] +synonym: "quinolinate breakdown" EXACT [] +synonym: "quinolinate catabolism" EXACT [] +synonym: "quinolinate degradation" EXACT [] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:0046874 ! quinolinate metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process + +[Term] +id: GO:0034214 +name: protein hexamerization +namespace: biological_process +def: "The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits." [GOC:ecd] +synonym: "protein hexamer assembly" EXACT [] +synonym: "protein hexamer biosynthesis" EXACT [] +synonym: "protein hexamer biosynthetic process" EXACT [] +synonym: "protein hexamer formation" EXACT [] +is_a: GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0034215 +name: thiamine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in)." [GOC:mah] +synonym: "thiamin:hydrogen symporter activity" EXACT [] +synonym: "thiamin:proton symporter activity" EXACT [] +synonym: "thiamine:hydrogen symporter activity" EXACT [] +is_a: GO:0015234 ! thiamine transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity + +[Term] +id: GO:0034216 +name: high-affinity thiamine:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mah] +synonym: "high affinity thiamin:hydrogen symporter activity" EXACT [] +synonym: "high-affinity thiamin:hydrogen symporter activity" EXACT [] +synonym: "high-affinity thiamin:proton symporter activity" EXACT [] +synonym: "high-affinity thiamine:hydrogen symporter activity" EXACT [] +is_a: GO:0034215 ! thiamine:proton symporter activity + +[Term] +id: GO:0034217 +name: ascospore wall chitin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores." [GOC:mah, GOC:vw] +synonym: "ascospore wall chitin anabolism" EXACT [] +synonym: "ascospore wall chitin biosynthesis" EXACT [] +synonym: "ascospore wall chitin formation" EXACT [] +synonym: "ascospore wall chitin synthesis" EXACT [] +is_a: GO:0034218 ! ascospore wall chitin metabolic process +is_a: GO:0034221 ! fungal-type cell wall chitin biosynthetic process +is_a: GO:0044106 ! cellular amine metabolic process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0070591 ! ascospore wall biogenesis + +[Term] +id: GO:0034218 +name: ascospore wall chitin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores." [GOC:mah, GOC:vw] +synonym: "ascospore wall chitin metabolism" EXACT [] +is_a: GO:0006037 ! cell wall chitin metabolic process +is_a: GO:0071966 ! fungal-type cell wall polysaccharide metabolic process + +[Term] +id: GO:0034219 +name: carbohydrate transmembrane transport +namespace: biological_process +def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "carbohydrate membrane transport" EXACT [] +synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034220 +name: ion transmembrane transport +namespace: biological_process +alt_id: GO:0099131 +def: "A process in which an ion is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "ATP hydrolysis coupled ion transmembrane transport" NARROW [] +synonym: "ion membrane transport" EXACT [] +synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006811 ! ion transport +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034221 +name: fungal-type cell wall chitin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells." [GOC:mah] +synonym: "fungal-type cell wall chitin anabolism" EXACT [] +synonym: "fungal-type cell wall chitin biosynthesis" EXACT [] +synonym: "fungal-type cell wall chitin formation" EXACT [] +synonym: "fungal-type cell wall chitin synthesis" EXACT [] +is_a: GO:0006038 ! cell wall chitin biosynthetic process +relationship: part_of GO:0009272 ! fungal-type cell wall biogenesis + +[Term] +id: GO:0034222 +name: regulation of cell wall chitin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall." [GOC:mah] +synonym: "regulation of cell wall chitin metabolism" EXACT [] +is_a: GO:0032882 ! regulation of chitin metabolic process +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006037 ! cell wall chitin metabolic process +relationship: regulates GO:0006037 ! cell wall chitin metabolic process + +[Term] +id: GO:0034223 +name: regulation of ascospore wall chitin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin." [GOC:mah] +synonym: "regulation of ascospore wall chitin anabolism" EXACT [] +synonym: "regulation of ascospore wall chitin biosynthesis" EXACT [] +synonym: "regulation of ascospore wall chitin formation" EXACT [] +synonym: "regulation of ascospore wall chitin synthesis" EXACT [] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0032884 ! regulation of cell wall chitin biosynthetic process +is_a: GO:0032995 ! regulation of fungal-type cell wall biogenesis +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0034307 ! regulation of ascospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034217 ! ascospore wall chitin biosynthetic process +relationship: regulates GO:0034217 ! ascospore wall chitin biosynthetic process + +[Term] +id: GO:0034224 +name: cellular response to zinc ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions." [GOC:mah] +synonym: "cellular response to zinc ion limitation" EXACT [] +synonym: "cellular response to zinc starvation" EXACT [] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0120127 ! response to zinc ion starvation + +[Term] +id: GO:0034225 +name: obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation +namespace: biological_process +def: "OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions." [GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of transcription from RNA polymerase II promoter in response to zinc deficiency" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0034227 +name: tRNA thio-modification +namespace: biological_process +def: "The addition a sulfur atom to a nucleotide in a tRNA molecule." [GOC:mcc, PMID:12549933, PMID:14722066] +synonym: "tRNA sulfurtransferase activity" RELATED [GOC:mah] +synonym: "tRNA thiolation" EXACT [PMID:24774365] +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0034228 +name: ethanolamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine." [GOC:rn, PMID:3514579] +synonym: "2-aminoethanol transmembrane transporter activity" EXACT [] +synonym: "ethanolamine permease activity" EXACT [] +synonym: "monoethanolamine transmembrane transporter activity" EXACT [] +xref: RHEA:32747 +is_a: GO:0005275 ! amine transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +relationship: part_of GO:0034229 ! ethanolamine transport + +[Term] +id: GO:0034229 +name: ethanolamine transport +namespace: biological_process +def: "The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine." [GOC:rn, PMID:3514579] +synonym: "2-aminoethanol transport" EXACT [] +synonym: "monoethanolamine transport" EXACT [] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015837 ! amine transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0034230 +name: enkephalin processing +namespace: biological_process +def: "The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide." [GOC:BHF, GOC:mah, GOC:rl, PMID:8262946] +synonym: "enkephalin formation" EXACT [] +synonym: "peptide enkephalin formation" EXACT [] +synonym: "peptide enkephalin processing" EXACT [] +is_a: GO:0016486 ! peptide hormone processing + +[Term] +id: GO:0034231 +name: islet amyloid polypeptide processing +namespace: biological_process +def: "The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP)." [GOC:BHF, GOC:rl, PMID:15983213, PMID:8262946] +synonym: "IAPP formation" EXACT [] +synonym: "IAPP processing" EXACT [] +synonym: "islet amyloid peptide formation" EXACT [] +synonym: "islet amyloid peptide processing" EXACT [] +synonym: "islet amyloid polypeptide formation" RELATED [] +is_a: GO:0016486 ! peptide hormone processing + +[Term] +id: GO:0034232 +name: ascospore wall chitin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall chitin breakdown" EXACT [] +synonym: "ascospore wall chitin catabolism" EXACT [] +synonym: "ascospore wall chitin degradation" EXACT [] +is_a: GO:0006039 ! cell wall chitin catabolic process +is_a: GO:0034218 ! ascospore wall chitin metabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +is_a: GO:0071854 ! cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly + +[Term] +id: GO:0034233 +name: regulation of cell wall chitin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin." [GOC:mah] +synonym: "regulation of cell wall chitin breakdown" EXACT [] +synonym: "regulation of cell wall chitin catabolism" EXACT [] +synonym: "regulation of cell wall chitin degradation" EXACT [] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0034222 ! regulation of cell wall chitin metabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006039 ! cell wall chitin catabolic process +relationship: regulates GO:0006039 ! cell wall chitin catabolic process + +[Term] +id: GO:0034234 +name: regulation of ascospore wall chitin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin." [GOC:mah] +synonym: "regulation of ascospore wall chitin breakdown" EXACT [] +synonym: "regulation of ascospore wall chitin catabolism" EXACT [] +synonym: "regulation of ascospore wall chitin degradation" EXACT [] +is_a: GO:0034233 ! regulation of cell wall chitin catabolic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0060237 ! regulation of fungal-type cell wall organization +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034232 ! ascospore wall chitin catabolic process +relationship: regulates GO:0034232 ! ascospore wall chitin catabolic process + +[Term] +id: GO:0034235 +name: GPI anchor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes." [GOC:vw] +comment: Note that this term should be used to annotate gene products that interact non-covalently with GPI anchors, and not proteins that have GPI anchors covalently attached. +synonym: "glycosylphosphatidylinositol binding" EXACT [] +is_a: GO:0035091 ! phosphatidylinositol binding +is_a: GO:0051861 ! glycolipid binding + +[Term] +id: GO:0034236 +name: protein kinase A catalytic subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A." [GOC:mah] +synonym: "PKA catalytic subunit binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding +is_a: GO:0051018 ! protein kinase A binding + +[Term] +id: GO:0034237 +name: protein kinase A regulatory subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A." [GOC:mah] +synonym: "PKA regulatory subunit binding" EXACT [] +synonym: "protein kinase A anchoring activity" RELATED [] +is_a: GO:0051018 ! protein kinase A binding + +[Term] +id: GO:0034238 +name: macrophage fusion +namespace: biological_process +def: "The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell." [GOC:sl] +is_a: GO:0000768 ! syncytium formation by plasma membrane fusion + +[Term] +id: GO:0034239 +name: regulation of macrophage fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage fusion." [GOC:mah] +is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034238 ! macrophage fusion +relationship: regulates GO:0034238 ! macrophage fusion + +[Term] +id: GO:0034240 +name: negative regulation of macrophage fusion +namespace: biological_process +def: "Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion." [GOC:mah] +is_a: GO:0034239 ! regulation of macrophage fusion +is_a: GO:0034242 ! negative regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034238 ! macrophage fusion +relationship: negatively_regulates GO:0034238 ! macrophage fusion + +[Term] +id: GO:0034241 +name: positive regulation of macrophage fusion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage fusion." [GOC:mah] +is_a: GO:0034239 ! regulation of macrophage fusion +is_a: GO:0060143 ! positive regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034238 ! macrophage fusion +relationship: positively_regulates GO:0034238 ! macrophage fusion + +[Term] +id: GO:0034242 +name: negative regulation of syncytium formation by plasma membrane fusion +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion +relationship: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion + +[Term] +id: GO:0034243 +name: regulation of transcription elongation from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:0090039 +def: "Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah, GOC:txnOH] +synonym: "regulation of gene-specific transcription elongation from RNA polymerase II promoter" RELATED [] +synonym: "regulation of RNA elongation from RNA polymerase II promoter" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0032784 ! regulation of DNA-templated transcription, elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter +relationship: regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter + +[Term] +id: GO:0034244 +name: negative regulation of transcription elongation from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:0090041 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah, GOC:txnOH] +synonym: "negative regulation of gene-specific transcription elongation from RNA polymerase II promoter" RELATED [] +synonym: "negative regulation of RNA elongation from RNA polymerase II promoter" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0032785 ! negative regulation of DNA-templated transcription, elongation +is_a: GO:0034243 ! regulation of transcription elongation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter +relationship: negatively_regulates GO:0006368 ! transcription elongation from RNA polymerase II promoter + +[Term] +id: GO:0034245 +name: mitochondrial DNA-directed RNA polymerase complex +namespace: cellular_component +def: "A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form." [GOC:krc, GOC:mah, PMID:7929382] +synonym: "mitochondrial RNA polymerase complex" BROAD [] +synonym: "mitochondrial RNA polymerase holoenzyme complex" EXACT [] +is_a: GO:0000428 ! DNA-directed RNA polymerase complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0034246 +name: mitochondrial sequence-specific DNA-binding transcription factor activity +namespace: molecular_function +alt_id: GO:0000998 +alt_id: GO:0001142 +alt_id: GO:0001143 +alt_id: GO:0001144 +def: "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by mitochondrial RNA polymerase." [GOC:txnOH-2018, PMID:18391175] +synonym: "mitochondrial polymerase transcription factor activity" EXACT [] +synonym: "mitochondrial RNA polymerase binding promoter specificity activity" EXACT [] +synonym: "mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "mitochondrial RNA polymerase promoter specificity activity" RELATED [] +synonym: "mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding" EXACT [] +synonym: "mitochondrial sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "mitochondrial transcription factor activity" RELATED [] +synonym: "mitochondrial transcription initiation factor activity" EXACT [] +synonym: "sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity" EXACT [] +synonym: "transcription factor activity, mitochondrial proximal promoter sequence-specific binding" EXACT [] +synonym: "transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding" EXACT [] +synonym: "transcription factor activity, mitochondrial RNA polymerase core promoter sequence-specific DNA binding" EXACT [] +is_a: GO:0003700 ! DNA-binding transcription factor activity +intersection_of: GO:0003700 ! DNA-binding transcription factor activity +intersection_of: has_part GO:0001001 ! mitochondrial single-subunit type RNA polymerase binding +intersection_of: has_part GO:0001018 ! mitochondrial promoter sequence-specific DNA binding +relationship: has_part GO:0001001 ! mitochondrial single-subunit type RNA polymerase binding +relationship: has_part GO:0001018 ! mitochondrial promoter sequence-specific DNA binding +relationship: part_of GO:0006390 ! mitochondrial transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14908 xsd:anyURI +created_by: krc +creation_date: 2011-01-27T01:55:21Z + +[Term] +id: GO:0034247 +name: snoRNA splicing +namespace: biological_process +def: "The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA." [GOC:mah] +is_a: GO:0008380 ! RNA splicing +is_a: GO:0043144 ! snoRNA processing + +[Term] +id: GO:0034248 +name: regulation of cellular amide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] +synonym: "regulation of amide metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043603 ! cellular amide metabolic process +relationship: regulates GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0034249 +name: negative regulation of cellular amide metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] +synonym: "negative regulation of amide metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043603 ! cellular amide metabolic process +relationship: negatively_regulates GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0034250 +name: positive regulation of cellular amide metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] +synonym: "positive regulation of amide metabolism" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043603 ! cellular amide metabolic process +relationship: positively_regulates GO:0043603 ! cellular amide metabolic process + +[Term] +id: GO:0034251 +name: regulation of cellular amide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] +synonym: "regulation of amide breakdown" EXACT [] +synonym: "regulation of amide catabolism" EXACT [] +synonym: "regulation of amide degradation" EXACT [] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043605 ! cellular amide catabolic process +relationship: regulates GO:0043605 ! cellular amide catabolic process + +[Term] +id: GO:0034252 +name: negative regulation of cellular amide catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] +synonym: "negative regulation of amide breakdown" EXACT [] +synonym: "negative regulation of amide catabolism" EXACT [] +synonym: "negative regulation of amide degradation" RELATED [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0034251 ! regulation of cellular amide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043605 ! cellular amide catabolic process +relationship: negatively_regulates GO:0043605 ! cellular amide catabolic process + +[Term] +id: GO:0034253 +name: positive regulation of cellular amide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] +synonym: "positive regulation of amide breakdown" EXACT [] +synonym: "positive regulation of amide catabolism" EXACT [] +synonym: "positive regulation of amide degradation" RELATED [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0034251 ! regulation of cellular amide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043605 ! cellular amide catabolic process +relationship: positively_regulates GO:0043605 ! cellular amide catabolic process + +[Term] +id: GO:0034254 +name: regulation of urea catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea." [GOC:mah] +synonym: "regulation of urea breakdown" EXACT [] +synonym: "regulation of urea catabolism" EXACT [] +synonym: "regulation of urea degradation" EXACT [] +is_a: GO:0034251 ! regulation of cellular amide catabolic process +is_a: GO:0034255 ! regulation of urea metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043419 ! urea catabolic process +relationship: regulates GO:0043419 ! urea catabolic process + +[Term] +id: GO:0034255 +name: regulation of urea metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea." [GOC:mah] +synonym: "regulation of urea metabolism" EXACT [] +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1903314 ! regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019627 ! urea metabolic process +relationship: regulates GO:0019627 ! urea metabolic process + +[Term] +id: GO:0034256 +name: chlorophyll(ide) b reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+." [EC:1.1.1.294, MetaCyc:RXN-7678] +synonym: "Chl b reductase activity" EXACT [] +synonym: "chlorophyll b reductase activity" EXACT [] +synonym: "chlorophyllide b reductase activity" EXACT [] +xref: EC:1.1.1.294 +xref: MetaCyc:RXN-7678 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034257 +name: nicotinamide riboside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other." [GOC:se] +xref: RHEA:33163 +is_a: GO:0005337 ! nucleoside transmembrane transporter activity +relationship: part_of GO:0034258 ! nicotinamide riboside transport + +[Term] +id: GO:0034258 +name: nicotinamide riboside transport +namespace: biological_process +def: "The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:se] +is_a: GO:0015858 ! nucleoside transport + +[Term] +id: GO:0034260 +name: negative regulation of GTPase activity +namespace: biological_process +alt_id: GO:0034259 +alt_id: GO:0034261 +alt_id: GO:1902264 +alt_id: GO:1902881 +def: "Any process that stops or reduces the rate of GTP hydrolysis by a GTPase." [GO_REF:0000058, GOC:mah, GOC:rb, GOC:TermGenie, PMID:16143306, PMID:24335649] +comment: An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649. +synonym: "down regulation of GTPase activity" EXACT [] +synonym: "down regulation of Rab GTPase activity" NARROW [GOC:pf] +synonym: "down regulation of Ras GTPase activity" NARROW [] +synonym: "down regulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of Rho GTPase activity" NARROW [] +synonym: "down-regulation of GTPase activity" EXACT [] +synonym: "down-regulation of Rab GTPase activity" NARROW [GOC:pf] +synonym: "down-regulation of Ras GTPase activity" NARROW [] +synonym: "down-regulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of Rho GTPase activity" NARROW [] +synonym: "downregulation of GTPase activity" EXACT [] +synonym: "downregulation of Rab GTPase activity" NARROW [GOC:pf] +synonym: "downregulation of Ras GTPase activity" NARROW [] +synonym: "downregulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of Rho GTPase activity" NARROW [] +synonym: "inhibition of GTPase activity" NARROW [] +synonym: "inhibition of Rab GTPase activity" NARROW [GOC:pf] +synonym: "inhibition of Ras GTPase activity" NARROW [] +synonym: "inhibition of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Rho GTPase activity" NARROW [] +synonym: "negative regulation of guanosinetriphosphatase activity" EXACT [] +synonym: "negative regulation of Rab GTPase activity" NARROW [] +synonym: "negative regulation of Ran GTPase activity" NARROW [] +synonym: "negative regulation of Ras GTPase activity" NARROW [] +synonym: "negative regulation of Rho GTPase activity" NARROW [] +is_a: GO:0043087 ! regulation of GTPase activity +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003924 ! GTPase activity +relationship: negatively_regulates GO:0003924 ! GTPase activity + +[Term] +id: GO:0034263 +name: positive regulation of autophagy in response to ER overload +namespace: biological_process +def: "The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy." [GOC:mah] +synonym: "autophagy in response to endoplasmic reticulum overload" EXACT [] +synonym: "autophagy in response to ER stress" EXACT [] +is_a: GO:0006983 ! ER overload response +is_a: GO:0010508 ! positive regulation of autophagy +intersection_of: GO:0006983 ! ER overload response +intersection_of: positively_regulates GO:0006914 ! autophagy + +[Term] +id: GO:0034264 +name: isopentenyl adenine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine." [GOC:mah, PMID:18216168] +synonym: "isopentenyl adenine metabolism" EXACT [] +synonym: "isopentenyladenine metabolic process" EXACT [] +is_a: GO:0009690 ! cytokinin metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0034265 +name: isopentenyl adenine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine." [GOC:mah, PMID:18216168] +synonym: "isopentenyl adenine anabolism" EXACT [] +synonym: "isopentenyl adenine biosynthesis" EXACT [] +synonym: "isopentenyl adenine formation" EXACT [] +synonym: "isopentenyl adenine synthesis" EXACT [] +synonym: "isopentenyladenine biosynthetic process" EXACT [] +is_a: GO:0009691 ! cytokinin biosynthetic process +is_a: GO:0034264 ! isopentenyl adenine metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0034266 +name: isopentenyl adenine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine." [GOC:mah, PMID:18216168] +synonym: "isopentenyl adenine breakdown" EXACT [] +synonym: "isopentenyl adenine catabolism" EXACT [] +synonym: "isopentenyl adenine degradation" EXACT [] +synonym: "isopentenyladenine catabolic process" EXACT [] +is_a: GO:0009823 ! cytokinin catabolic process +is_a: GO:0034264 ! isopentenyl adenine metabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process + +[Term] +id: GO:0034267 +name: discadenine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid." [GOC:mah] +synonym: "discadenine metabolism" EXACT [] +is_a: GO:0009690 ! cytokinin metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0034268 +name: discadenine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid." [GOC:mah] +synonym: "discadenine anabolism" EXACT [] +synonym: "discadenine biosynthesis" EXACT [] +synonym: "discadenine formation" EXACT [] +synonym: "discadenine synthesis" EXACT [] +is_a: GO:0009691 ! cytokinin biosynthetic process +is_a: GO:0034267 ! discadenine metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0034269 +name: discadenine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid." [GOC:mah] +synonym: "discadenine breakdown" EXACT [] +synonym: "discadenine catabolism" EXACT [] +synonym: "discadenine degradation" EXACT [] +is_a: GO:0009823 ! cytokinin catabolic process +is_a: GO:0034267 ! discadenine metabolic process +is_a: GO:0072523 ! purine-containing compound catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0034270 +name: Cvt complex +namespace: cellular_component +def: "A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p." [GOC:rb, PMID:15659643] +synonym: "cytoplasm to vacuole targeting complex" EXACT [] +synonym: "cytoplasm-to-vacuole targeting complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034271 +name: phosphatidylinositol 3-kinase complex, class III, type I +namespace: cellular_component +def: "A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p." [GOC:ha, GOC:rb, PMID:11157979, PMID:16421251] +comment: Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'. +synonym: "autophagy-specific phosphatidylinositol 3-kinase (PtdIns3K) complex" EXACT [] +synonym: "phosphatidylinositol 3-kinase complex I" RELATED [] +synonym: "PtdIns-3-kinase complex I" RELATED [] +is_a: GO:0035032 ! phosphatidylinositol 3-kinase complex, class III + +[Term] +id: GO:0034272 +name: phosphatidylinositol 3-kinase complex, class III, type II +namespace: cellular_component +def: "A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p." [GOC:ha, GOC:rb, PMID:11157979, PMID:16421251] +comment: Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'. +synonym: "phosphatidylinositol 3-kinase complex II" RELATED [] +synonym: "PtdIns-3-kinase complex II" RELATED [] +is_a: GO:0035032 ! phosphatidylinositol 3-kinase complex, class III + +[Term] +id: GO:0034274 +name: Atg12-Atg5-Atg16 complex +namespace: cellular_component +def: "A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p." [GOC:rb, PMID:17986448] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034275 +name: kynurenic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid." [GOC:mah] +synonym: "4-hydroxyquinoline-2-carboxylic acid metabolic process" EXACT [] +synonym: "kynurenic acid metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0034276 +name: kynurenic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid." [GOC:mah] +synonym: "4-hydroxyquinoline-2-carboxylic acid biosynthetic process" EXACT [] +synonym: "kynurenic acid anabolism" EXACT [] +synonym: "kynurenic acid biosynthesis" EXACT [] +synonym: "kynurenic acid formation" RELATED [] +synonym: "kynurenic acid synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0034275 ! kynurenic acid metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0034277 +name: ent-cassa-12,15-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate." [EC:4.2.3.28, RHEA:25532] +synonym: "ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity" EXACT systematic_synonym [EC:4.2.3.28, KEGG_REACTION:R09119] +xref: EC:4.2.3.28 +xref: KEGG_REACTION:R09119 +xref: MetaCyc:RXN-4881 +xref: RHEA:25532 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034278 +name: stemar-13-ene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate." [MetaCyc:RXN-4882, RHEA:25552] +synonym: "9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity" EXACT systematic_synonym [KEGG_REACTION:R09115] +xref: EC:4.2.3.33 +xref: KEGG_REACTION:R09115 +xref: MetaCyc:RXN-4882 +xref: RHEA:25552 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034279 +name: syn-pimara-7,15-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate." [MetaCyc:RXN-4883, RHEA:25560] +synonym: "9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity" EXACT systematic_synonym [KEGG_REACTION:R09117] +xref: EC:4.2.3.35 +xref: KEGG_REACTION:R09117 +xref: MetaCyc:RXN-4883 +xref: RHEA:25560 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034280 +name: ent-sandaracopimaradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate." [MetaCyc:RXN-4884, RHEA:25536] +synonym: "ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity" EXACT systematic_synonym [KEGG_REACTION:R09120] +synonym: "ent-pimaradiene synthase activity" BROAD [] +xref: EC:4.2.3.29 +xref: KEGG_REACTION:R09120 +xref: MetaCyc:RXN-4884 +xref: RHEA:25536 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034281 +name: ent-isokaurene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate." [PMID:17141283] +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0034282 +name: ent-pimara-8(14),15-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate." [RHEA:25540] +synonym: "ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity" EXACT systematic_synonym [KEGG_REACTION:R09121] +synonym: "ent-pimaradiene synthase activity" BROAD [] +xref: EC:4.2.3.30 +xref: KEGG_REACTION:R09121 +xref: MetaCyc:RXN-7788 +xref: RHEA:25540 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034283 +name: syn-stemod-13(17)-ene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate." [RHEA:25556] +synonym: "9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity" EXACT systematic_synonym [KEGG_REACTION:R09116] +synonym: "exo-stemodene synthase activity" EXACT [] +synonym: "stemod-13(17)-ene synthase activity" EXACT [] +synonym: "stemodene synthase activity" EXACT [] +synonym: "syn-stemodene synthase activity" EXACT [] +xref: EC:4.2.3.34 +xref: KEGG_REACTION:R09116 +xref: MetaCyc:RXN-9291 +xref: RHEA:25556 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034284 +name: response to monosaccharide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] +synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] +is_a: GO:0009743 ! response to carbohydrate + +[Term] +id: GO:0034285 +name: response to disaccharide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus." [GOC:sart] +synonym: "response to disaccharide stimulus" EXACT [GOC:dos] +is_a: GO:0009743 ! response to carbohydrate + +[Term] +id: GO:0034286 +name: response to maltose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus." [GOC:sart] +synonym: "response to maltose stimulus" EXACT [GOC:dos] +is_a: GO:0034285 ! response to disaccharide + +[Term] +id: GO:0034287 +name: detection of monosaccharide stimulus +namespace: biological_process +def: "The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal." [GOC:mah] +synonym: "perception of monosaccharide stimulus" RELATED [] +is_a: GO:0009730 ! detection of carbohydrate stimulus +is_a: GO:0034284 ! response to monosaccharide + +[Term] +id: GO:0034288 +name: detection of disaccharide stimulus +namespace: biological_process +def: "The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal." [GOC:sart] +synonym: "perception of disaccharide stimulus" RELATED [] +is_a: GO:0009730 ! detection of carbohydrate stimulus +is_a: GO:0034285 ! response to disaccharide + +[Term] +id: GO:0034289 +name: detection of maltose stimulus +namespace: biological_process +def: "The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal." [GOC:sart] +synonym: "perception of maltose stimulus" RELATED [] +is_a: GO:0034286 ! response to maltose +is_a: GO:0034288 ! detection of disaccharide stimulus + +[Term] +id: GO:0034290 +name: holin activity +namespace: molecular_function +def: "A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate." [GOC:jh2, PMID:1406491, PMID:25157079] +is_a: GO:0015267 ! channel activity +relationship: part_of GO:0044660 ! viral release by cytolysis via pore formation in host cell membrane + +[Term] +id: GO:0034291 +name: canonical holin activity +namespace: molecular_function +def: "A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell." [GOC:jh2, GOC:mah, PMID:1406491, PMID:25157079] +is_a: GO:0034290 ! holin activity + +[Term] +id: GO:0034292 +name: pinholin activity +namespace: molecular_function +def: "A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall." [GOC:jh2, GOC:mah, PMID:1406491, PMID:25157079] +is_a: GO:0005216 ! ion channel activity +is_a: GO:0034290 ! holin activity + +[Term] +id: GO:0034293 +name: sexual sporulation +namespace: biological_process +def: "The formation of spores derived from the products of meiosis." [GOC:mah] +subset: goslim_aspergillus +synonym: "meiotic spore formation" EXACT [] +synonym: "meiotic sporulation" EXACT [] +synonym: "sexual spore formation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0043934 ! sporulation +intersection_of: GO:0043934 ! sporulation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0019953 ! sexual reproduction +relationship: part_of GO:0051321 ! meiotic cell cycle +property_value: RO:0002161 NCBITaxon:33083 + +[Term] +id: GO:0034294 +name: sexual spore wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis." [GOC:mah] +synonym: "sexual spore wall formation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0042244 ! spore wall assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0034293 ! sexual sporulation + +[Term] +id: GO:0034295 +name: basidiospore formation +namespace: biological_process +def: "The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium." [GOC:di, GOC:ds, GOC:mah, GOC:mcc, http://www.gsbs.utmb.edu/microbook/ch073.htm, http://www.ilmyco.gen.chicago.il.us/Terms/basid133.html] +comment: Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked. +is_a: GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034296 +name: zygospore formation +namespace: biological_process +def: "The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away." [GOC:ds, GOC:mah, http://www.ilmyco.gen.chicago.il.us/Terms/zygos581.html] +is_a: GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034297 +name: oidium formation +namespace: biological_process +def: "The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus." [GOC:mah, http://www.ilmyco.gen.chicago.il.us/Terms/oidiu163.html] +is_a: GO:0030436 ! asexual sporulation + +[Term] +id: GO:0034298 +name: arthrospore formation +namespace: biological_process +def: "The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation." [GOC:mah] +synonym: "arthroconidium formation" EXACT [] +is_a: GO:0048315 ! conidium formation +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0034299 +name: reproductive blastospore formation +namespace: biological_process +def: "The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota." [GOC:mah, http://bugs.bio.usyd.edu.au/Mycology/Glossary/glossary_a_b.shtml#blastospore, http://bugs.bio.usyd.edu.au/Mycology/Taxonomy/glomeromycota.shtml] +comment: Note that this term should not be confused with the usage of 'blastospore' to mean any yeast-form fungal cell, as in Candida species. +synonym: "blastoconidium formation" EXACT [http://cancerweb.ncl.ac.uk/cgi-bin/omd?Blastoconidium] +is_a: GO:0048315 ! conidium formation +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0034300 +name: sporangiospore formation +namespace: biological_process +def: "The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm." [GOC:ds, GOC:mah, http://bugs.bio.usyd.edu.au/Mycology/Glossary/glossary_n_z.shtml] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034301 +name: endospore formation +namespace: biological_process +def: "The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions." [GOC:ds, GOC:mah, ISBN:0470090278] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034302 +name: akinete formation +namespace: biological_process +def: "The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria." [GOC:ds, GOC:mah, http://www.msu.edu/course/bot/423/algalglossary.htm#Reproductive, PMID:11948167] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034303 +name: myxospore formation +namespace: biological_process +def: "The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria." [GOC:ds, ISBN:0122268008] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034304 +name: actinomycete-type spore formation +namespace: biological_process +def: "The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales." [GOC:ds, ISBN:0122268008] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022413 ! reproductive process in single-celled organism +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0034305 +name: regulation of asexual sporulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis." [GOC:mah] +synonym: "regulation of asexual spore formation" EXACT [] +synonym: "regulation of mitotic spore formation" EXACT [] +synonym: "regulation of mitotic sporulation" EXACT [] +is_a: GO:0043937 ! regulation of sporulation +is_a: GO:1903664 ! regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030436 ! asexual sporulation +relationship: regulates GO:0030436 ! asexual sporulation + +[Term] +id: GO:0034306 +name: regulation of sexual sporulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae." [GOC:mah] +synonym: "MAPKKK cascade during sporulation" RELATED [] +synonym: "regulation of meiotic spore formation" EXACT [] +synonym: "regulation of meiotic sporulation" EXACT [] +synonym: "regulation of sexual spore formation" EXACT [] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0043937 ! regulation of sporulation +is_a: GO:0051445 ! regulation of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034293 ! sexual sporulation +relationship: regulates GO:0034293 ! sexual sporulation + +[Term] +id: GO:0034307 +name: regulation of ascospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae." [GOC:mah] +synonym: "MAPKKK cascade during sporulation" RELATED [] +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030437 ! ascospore formation +relationship: regulates GO:0030437 ! ascospore formation + +[Term] +id: GO:0034308 +name: primary alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] +synonym: "monohydric alcohol metabolic process" EXACT [] +synonym: "primary alcohol metabolism" EXACT [GOC:mah] +is_a: GO:0006066 ! alcohol metabolic process + +[Term] +id: GO:0034309 +name: primary alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] +synonym: "monohydric alcohol biosynthetic process" EXACT [] +synonym: "primary alcohol anabolism" EXACT [GOC:mah] +synonym: "primary alcohol biosynthesis" EXACT [GOC:mah] +synonym: "primary alcohol formation" EXACT [GOC:mah] +synonym: "primary alcohol synthesis" EXACT [GOC:mah] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0046165 ! alcohol biosynthetic process + +[Term] +id: GO:0034310 +name: primary alcohol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." [GOC:mah] +synonym: "monohydric alcohol catabolic process" EXACT [] +synonym: "primary alcohol breakdown" EXACT [GOC:mah] +synonym: "primary alcohol catabolism" EXACT [GOC:mah] +synonym: "primary alcohol degradation" EXACT [GOC:mah] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0034311 +name: diol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic." [GOC:curators] +synonym: "dihydric alcohol metabolic process" RELATED [] +synonym: "diol metabolism" EXACT [] +is_a: GO:0019751 ! polyol metabolic process + +[Term] +id: GO:0034312 +name: diol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms." [GOC:mah] +synonym: "dihydric alcohol biosynthetic process" EXACT [] +synonym: "diol anabolism" EXACT [] +synonym: "diol biosynthesis" EXACT [] +synonym: "diol formation" EXACT [] +synonym: "diol synthesis" EXACT [] +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0046173 ! polyol biosynthetic process + +[Term] +id: GO:0034313 +name: diol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms." [GOC:mah] +synonym: "dihydric alcohol catabolic process" EXACT [] +synonym: "diol breakdown" EXACT [] +synonym: "diol catabolism" EXACT [] +synonym: "diol degradation" EXACT [] +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0046174 ! polyol catabolic process + +[Term] +id: GO:0034314 +name: Arp2/3 complex-mediated actin nucleation +namespace: biological_process +def: "The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins." [GOC:mah, PMID:16959963, PMID:18640983] +synonym: "actin filament branch nucleation" EXACT [] +synonym: "branched actin filament nucleation" EXACT [] +is_a: GO:0045010 ! actin nucleation + +[Term] +id: GO:0034315 +name: regulation of Arp2/3 complex-mediated actin nucleation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins." [GOC:mah] +is_a: GO:0051125 ! regulation of actin nucleation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation +relationship: regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation + +[Term] +id: GO:0034316 +name: negative regulation of Arp2/3 complex-mediated actin nucleation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins." [GOC:mah, PMID:16959963] +is_a: GO:0034315 ! regulation of Arp2/3 complex-mediated actin nucleation +is_a: GO:0051126 ! negative regulation of actin nucleation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation +relationship: negatively_regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation + +[Term] +id: GO:0034317 +name: nicotinic acid riboside kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide." [PMID:17914902] +xref: MetaCyc:RXN-8443 +is_a: GO:0019206 ! nucleoside kinase activity + +[Term] +id: GO:0034318 +name: alcohol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule." [GOC:mah] +synonym: "acyl-CoA:alcohol O-acyltransferase activity" EXACT [] +synonym: "acyl-CoA:ethanol O-acyltransferase" NARROW [] +synonym: "acyl-coenzymeA:alcohol O-acyltransferase activity" EXACT [] +synonym: "acyl-coenzymeA:ethanol O-acyltransferase activity" NARROW [] +synonym: "AEATase activity" NARROW [] +synonym: "alcohol acyltransferase activity" EXACT [] +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0034319 +name: alcohol O-butanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester." [GOC:mah, PMID:16361250] +is_a: GO:0016413 ! O-acetyltransferase activity +is_a: GO:0034318 ! alcohol O-acyltransferase activity +is_a: GO:0034323 ! O-butanoyltransferase activity + +[Term] +id: GO:0034320 +name: alcohol O-hexanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester." [GOC:mah, PMID:16361250] +is_a: GO:0016413 ! O-acetyltransferase activity +is_a: GO:0034318 ! alcohol O-acyltransferase activity +is_a: GO:0034324 ! O-hexanoyltransferase activity + +[Term] +id: GO:0034321 +name: alcohol O-octanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester." [GOC:mah, PMID:16361250] +is_a: GO:0016413 ! O-acetyltransferase activity +is_a: GO:0016414 ! O-octanoyltransferase activity +is_a: GO:0034318 ! alcohol O-acyltransferase activity + +[Term] +id: GO:0034322 +name: alcohol O-decanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester." [GOC:mah, PMID:16361250] +is_a: GO:0016413 ! O-acetyltransferase activity +is_a: GO:0034318 ! alcohol O-acyltransferase activity +is_a: GO:0034325 ! O-decanoyltransferase activity + +[Term] +id: GO:0034323 +name: O-butanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule." [GOC:mah] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0034326 ! butanoyltransferase activity + +[Term] +id: GO:0034324 +name: O-hexanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule." [GOC:mah] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0034327 ! hexanoyltransferase activity + +[Term] +id: GO:0034325 +name: O-decanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule." [GOC:mah] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0034328 ! decanoyltransferase activity + +[Term] +id: GO:0034326 +name: butanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule." [GOC:mah] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034327 +name: hexanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule." [GOC:mah] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034328 +name: decanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule." [GOC:mah] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034329 +name: cell junction assembly +namespace: biological_process +def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0034330 ! cell junction organization + +[Term] +id: GO:0034330 +name: cell junction organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "cell junction assembly and maintenance" EXACT [] +synonym: "cell junction biogenesis" RELATED [] +synonym: "cell junction organisation" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0034331 +name: cell junction maintenance +namespace: biological_process +def: "The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] +is_a: GO:0034330 ! cell junction organization +is_a: GO:0043954 ! cellular component maintenance + +[Term] +id: GO:0034332 +name: adherens junction organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GOC:aruk, GOC:bc, GOC:dph, GOC:jl, GOC:mah] +synonym: "adherens junction organisation" EXACT [] +is_a: GO:0045216 ! cell-cell junction organization +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0034333 +name: adherens junction assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GOC:aruk, GOC:bc, GOC:mah] +synonym: "adherens junction formation" EXACT [] +is_a: GO:0007043 ! cell-cell junction assembly +is_a: GO:0034332 ! adherens junction organization + +[Term] +id: GO:0034334 +name: adherens junction maintenance +namespace: biological_process +def: "The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GOC:aruk, GOC:bc, GOC:mah] +is_a: GO:0034332 ! adherens junction organization +is_a: GO:0045217 ! cell-cell junction maintenance + +[Term] +id: GO:0034335 +name: DNA negative supercoiling activity +namespace: molecular_function +def: "Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria." [GOC:bhm, GOC:krc, GOC:mah, WikiPedia:DNA_gyrase] +comment: Note that this term was reinstated from obsolete. +synonym: "DNA gyrase activity" RELATED [] +synonym: "DNA-gyrase activity" RELATED [] +is_a: GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity + +[Term] +id: GO:0034336 +name: misfolded RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation." [GOC:mah, PMID:10393192] +synonym: "RNA chaperone" RELATED [] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0034337 +name: RNA folding +namespace: biological_process +def: "The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure." [GOC:mah, PMID:10393192] +synonym: "RNA chaperone" RELATED [] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0034338 +name: short-chain carboxylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms." [GOC:jp] +synonym: "butyrate esterase activity" NARROW [] +synonym: "butyryl esterase activity" NARROW [] +synonym: "methylbutyrase activity" NARROW [] +synonym: "methylbutyrate esterase activity" NARROW [] +synonym: "monobutyrase activity" NARROW [] +synonym: "propionyl esterase activity" NARROW [] +synonym: "short-chain esterase activity" BROAD [] +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0034339 +name: obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor +namespace: biological_process +def: "OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GO_REF:0000021, GOC:mah, GOC:mh] +comment: This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand. +synonym: "regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor" EXACT [] +is_obsolete: true +consider: GO:0004879 +consider: GO:0006357 +consider: GO:0030374 +consider: GO:0030522 + +[Term] +id: GO:0034340 +name: response to type I interferon +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834] +synonym: "response to type I IFN" EXACT [] +is_a: GO:0034097 ! response to cytokine +relationship: part_of GO:0045087 ! innate immune response + +[Term] +id: GO:0034341 +name: response to interferon-gamma +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon." [GOC:add, ISBN:0126896631, PMID:15546383] +synonym: "response to gamma-interferon" RELATED [] +synonym: "response to immune interferon" EXACT [] +synonym: "response to type II IFN" BROAD [] +synonym: "response to type II interferon" BROAD [] +is_a: GO:0034097 ! response to cytokine +relationship: part_of GO:0045087 ! innate immune response + +[Term] +id: GO:0034342 +name: response to type III interferon +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +synonym: "response to interferon-lambda" NARROW [] +synonym: "response to type III IFN" EXACT [] +is_a: GO:0034097 ! response to cytokine +relationship: part_of GO:0045087 ! innate immune response + +[Term] +id: GO:0034343 +name: type III interferon production +namespace: biological_process +def: "The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "type III IFN production" EXACT [] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0034344 +name: regulation of type III interferon production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "regulation of type III IFN production" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034343 ! type III interferon production +relationship: regulates GO:0034343 ! type III interferon production + +[Term] +id: GO:0034345 +name: negative regulation of type III interferon production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "down regulation of type III interferon production" EXACT [] +synonym: "down-regulation of type III interferon production" EXACT [] +synonym: "downregulation of type III interferon production" EXACT [] +synonym: "inhibition of type III interferon production" NARROW [] +synonym: "negative regulation of type III IFN production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0034344 ! regulation of type III interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034343 ! type III interferon production +relationship: negatively_regulates GO:0034343 ! type III interferon production + +[Term] +id: GO:0034346 +name: positive regulation of type III interferon production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "activation of type III interferon production" NARROW [] +synonym: "positive regulation of type III IFN production" EXACT [] +synonym: "stimulation of type III interferon production" NARROW [] +synonym: "up regulation of type III interferon production" EXACT [] +synonym: "up-regulation of type III interferon production" EXACT [] +synonym: "upregulation of type III interferon production" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0034344 ! regulation of type III interferon production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034343 ! type III interferon production +relationship: positively_regulates GO:0034343 ! type III interferon production + +[Term] +id: GO:0034347 +name: type III interferon binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type III interferon. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "interferon-lambda binding" NARROW [] +is_a: GO:0019961 ! interferon binding + +[Term] +id: GO:0034348 +name: type III interferon receptor activity +namespace: molecular_function +def: "Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far." [GOC:add, GOC:signaling, ISBN:0126896631, PMID:15546383, PMID:16734557] +comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. +synonym: "interferon-lambda receptor activity" NARROW [PR:000001362] +is_a: GO:0004904 ! interferon receptor activity +relationship: has_part GO:0034347 ! type III interferon binding +relationship: part_of GO:0038196 ! type III interferon signaling pathway + +[Term] +id: GO:0034349 +name: glial cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart] +synonym: "apoptosis of glia" EXACT [] +synonym: "apoptosis of glial cells" EXACT [] +synonym: "glia apoptosis" EXACT [] +synonym: "glia programmed cell death by apoptosis" EXACT [] +synonym: "glial cell apoptosis" NARROW [] +synonym: "glial cell programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of glia by apoptosis" EXACT [] +synonym: "programmed cell death of glial cells by apoptosis" EXACT [] +synonym: "programmed cell death, glia" EXACT [] +synonym: "programmed cell death, glial cells" EXACT [] +is_a: GO:0006915 ! apoptotic process + +[Term] +id: GO:0034350 +name: regulation of glial cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] +synonym: "regulation of glial cell apoptosis" RELATED [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034349 ! glial cell apoptotic process +relationship: regulates GO:0034349 ! glial cell apoptotic process + +[Term] +id: GO:0034351 +name: negative regulation of glial cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] +synonym: "down regulation of glial cell apoptosis" EXACT [] +synonym: "down-regulation of glial cell apoptosis" EXACT [] +synonym: "downregulation of glial cell apoptosis" EXACT [] +synonym: "inhibition of glial cell apoptosis" NARROW [] +synonym: "negative regulation of glial cell apoptosis" NARROW [] +is_a: GO:0034350 ! regulation of glial cell apoptotic process +is_a: GO:0043066 ! negative regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034349 ! glial cell apoptotic process +relationship: negatively_regulates GO:0034349 ! glial cell apoptotic process + +[Term] +id: GO:0034352 +name: positive regulation of glial cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] +synonym: "activation of glial cell apoptosis" NARROW [] +synonym: "positive regulation of glial cell apoptosis" NARROW [] +synonym: "stimulation of glial cell apoptosis" NARROW [] +synonym: "up regulation of glial cell apoptosis" EXACT [] +synonym: "up-regulation of glial cell apoptosis" EXACT [] +synonym: "upregulation of glial cell apoptosis" EXACT [] +is_a: GO:0034350 ! regulation of glial cell apoptotic process +is_a: GO:0043065 ! positive regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034349 ! glial cell apoptotic process +relationship: positively_regulates GO:0034349 ! glial cell apoptotic process + +[Term] +id: GO:0034353 +name: RNA pyrophosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end." [GOC:jh2, PMID:17612492, PMID:18202662] +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0034354 +name: 'de novo' NAD biosynthetic process from tryptophan +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [PMID:17161604] +synonym: "de novo NAD biosynthetic process from tryptophan" RELATED [] +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0034627 ! 'de novo' NAD biosynthetic process + +[Term] +id: GO:0034355 +name: NAD salvage +namespace: biological_process +def: "Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam)." [GOC:mah, PMID:12648681] +synonym: "NAD salvage pathway" EXACT [] +is_a: GO:0009435 ! NAD biosynthetic process +is_a: GO:0019365 ! pyridine nucleotide salvage + +[Term] +id: GO:0034356 +name: NAD biosynthesis via nicotinamide riboside salvage pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside." [PMID:17482543] +synonym: "nicotinamide riboside salvage pathway" EXACT [] +synonym: "NR salvage pathway" EXACT [] +is_a: GO:0009435 ! NAD biosynthetic process + +[Term] +id: GO:0034357 +name: photosynthetic membrane +namespace: cellular_component +def: "A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place." [GOC:ds, GOC:mah] +is_a: GO:0016020 ! membrane +relationship: part_of GO:0009579 ! thylakoid +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0034358 +name: plasma lipoprotein particle +namespace: cellular_component +def: "A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph." [GOC:BHF, GOC:expert_pt, GOC:rl] +is_a: GO:1990777 ! lipoprotein particle +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0034359 +name: mature chylomicron +namespace: cellular_component +def: "A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +is_a: GO:0042627 ! chylomicron + +[Term] +id: GO:0034360 +name: chylomicron remnant +namespace: cellular_component +def: "A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +is_a: GO:0042627 ! chylomicron + +[Term] +id: GO:0034361 +name: very-low-density lipoprotein particle +namespace: cellular_component +def: "A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "very-low-density lipoprotein complex" EXACT [] +synonym: "VLDL complex" EXACT [] +synonym: "VLDL particle" EXACT [] +is_a: GO:0034385 ! triglyceride-rich plasma lipoprotein particle + +[Term] +id: GO:0034362 +name: low-density lipoprotein particle +namespace: cellular_component +def: "A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "LDL complex" EXACT [] +synonym: "LDL particle" EXACT [] +synonym: "low-density lipoprotein complex" EXACT [] +is_a: GO:0034358 ! plasma lipoprotein particle + +[Term] +id: GO:0034363 +name: intermediate-density lipoprotein particle +namespace: cellular_component +def: "A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL)." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "IDL complex" EXACT [] +synonym: "IDL particle" EXACT [] +synonym: "intermediate-density lipoprotein complex" EXACT [] +is_a: GO:0034385 ! triglyceride-rich plasma lipoprotein particle + +[Term] +id: GO:0034364 +name: high-density lipoprotein particle +namespace: cellular_component +def: "A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:pde, GOC:rl] +synonym: "HDL complex" EXACT [] +synonym: "HDL particle" EXACT [] +synonym: "HDL2" RELATED [] +synonym: "HDL3" RELATED [] +synonym: "high-density lipoprotein class complex" EXACT [] +is_a: GO:0034358 ! plasma lipoprotein particle + +[Term] +id: GO:0034365 +name: discoidal high-density lipoprotein particle +namespace: cellular_component +def: "A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase)." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "discoidal HDL" EXACT [] +synonym: "nascent HDL" EXACT [] +synonym: "nascent high-density lipoprotein particle" EXACT [] +is_a: GO:0034364 ! high-density lipoprotein particle + +[Term] +id: GO:0034366 +name: spherical high-density lipoprotein particle +namespace: cellular_component +def: "A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT)." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "mature HDL" EXACT [] +synonym: "mature high-density lipoprotein particle" EXACT [] +synonym: "spherical HDL" EXACT [] +is_a: GO:0034364 ! high-density lipoprotein particle + +[Term] +id: GO:0034367 +name: protein-containing complex remodeling +namespace: biological_process +def: "The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex." [GOC:BHF, GOC:mah, GOC:mtg_mpo, GOC:rl] +synonym: "macromolecular complex remodeling" RELATED [] +is_a: GO:0043933 ! protein-containing complex subunit organization + +[Term] +id: GO:0034368 +name: protein-lipid complex remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a protein-lipid complex." [GOC:BHF, GOC:mah, GOC:rl] +is_a: GO:0034367 ! protein-containing complex remodeling +is_a: GO:0071825 ! protein-lipid complex subunit organization + +[Term] +id: GO:0034369 +name: plasma lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT)." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +is_a: GO:0034368 ! protein-lipid complex remodeling +is_a: GO:0071827 ! plasma lipoprotein particle organization +relationship: part_of GO:0097006 ! regulation of plasma lipoprotein particle levels + +[Term] +id: GO:0034370 +name: triglyceride-rich lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "triacylglycerol-rich lipoprotein particle remodeling" EXACT [GOC:mah] +is_a: GO:0034369 ! plasma lipoprotein particle remodeling + +[Term] +id: GO:0034371 +name: chylomicron remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "chylomicron remnant formation" RELATED [] +is_a: GO:0034370 ! triglyceride-rich lipoprotein particle remodeling + +[Term] +id: GO:0034372 +name: very-low-density lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "IDL formation" RELATED [] +synonym: "intermediate-density lipoprotein particle formation" RELATED [] +synonym: "VLDL remodeling" EXACT [] +is_a: GO:0034370 ! triglyceride-rich lipoprotein particle remodeling + +[Term] +id: GO:0034373 +name: intermediate-density lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "IDL remodeling" EXACT [] +synonym: "LDL formation" RELATED [] +synonym: "low-density lipoprotein particle formation" RELATED [] +is_a: GO:0034370 ! triglyceride-rich lipoprotein particle remodeling + +[Term] +id: GO:0034374 +name: low-density lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "LDL remodeling" EXACT [] +synonym: "small dense LDL formation" RELATED [GOC:BHF] +synonym: "small dense low-density lipoprotein particle formation" RELATED [GOC:BHF] +is_a: GO:0034369 ! plasma lipoprotein particle remodeling + +[Term] +id: GO:0034375 +name: high-density lipoprotein particle remodeling +namespace: biological_process +def: "The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL." [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl] +synonym: "HDL remodeling" EXACT [] +is_a: GO:0034369 ! plasma lipoprotein particle remodeling + +[Term] +id: GO:0034376 +name: conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle +namespace: biological_process +def: "The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle." [GOC:BHF, GOC:mah, GOC:pde] +synonym: "conversion of discoidal HDL to spherical HDL" EXACT [] +synonym: "discoidal HDL remodeling" RELATED [] +synonym: "discoidal high-density lipoprotein remodeling" RELATED [] +is_a: GO:0034375 ! high-density lipoprotein particle remodeling + +[Term] +id: GO:0034377 +name: plasma lipoprotein particle assembly +namespace: biological_process +def: "The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle." [GOC:BHF, GOC:mah] +is_a: GO:0065005 ! protein-lipid complex assembly +is_a: GO:0071827 ! plasma lipoprotein particle organization +relationship: part_of GO:0097006 ! regulation of plasma lipoprotein particle levels + +[Term] +id: GO:0034378 +name: chylomicron assembly +namespace: biological_process +def: "The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron." [GOC:BHF, GOC:mah] +is_a: GO:0034377 ! plasma lipoprotein particle assembly + +[Term] +id: GO:0034379 +name: very-low-density lipoprotein particle assembly +namespace: biological_process +def: "The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle." [GOC:BHF, GOC:mah] +synonym: "VLDL assembly" EXACT [] +is_a: GO:0034377 ! plasma lipoprotein particle assembly + +[Term] +id: GO:0034380 +name: high-density lipoprotein particle assembly +namespace: biological_process +def: "The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle." [GOC:BHF, GOC:mah] +synonym: "HDL assembly" EXACT [] +is_a: GO:0034377 ! plasma lipoprotein particle assembly + +[Term] +id: GO:0034381 +name: plasma lipoprotein particle clearance +namespace: biological_process +def: "The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:mah, GOC:tb] +synonym: "lipoprotein particle clearance" EXACT [GOC:mah] +is_a: GO:0032501 ! multicellular organismal process +relationship: has_part GO:0006898 ! receptor-mediated endocytosis +relationship: has_part GO:0071829 ! plasma lipoprotein particle disassembly +relationship: part_of GO:0097006 ! regulation of plasma lipoprotein particle levels + +[Term] +id: GO:0034382 +name: chylomicron remnant clearance +namespace: biological_process +def: "The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded." [GOC:BHF, GOC:mah, GOC:pde] +is_a: GO:0071830 ! triglyceride-rich lipoprotein particle clearance + +[Term] +id: GO:0034383 +name: low-density lipoprotein particle clearance +namespace: biological_process +def: "The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:mah] +synonym: "LDL clearance" EXACT [] +is_a: GO:0034381 ! plasma lipoprotein particle clearance +relationship: has_part GO:0090495 ! low-density lipoprotein particle disassembly + +[Term] +id: GO:0034384 +name: high-density lipoprotein particle clearance +namespace: biological_process +def: "The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:mah] +synonym: "HDL clearance" EXACT [] +is_a: GO:0034381 ! plasma lipoprotein particle clearance + +[Term] +id: GO:0034385 +name: triglyceride-rich plasma lipoprotein particle +namespace: cellular_component +def: "A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood." [GOC:BHF, GOC:mah, GOC:rl] +synonym: "triacylglycerol-rich lipoprotein particle" NARROW [GOC:mah] +synonym: "triglyceride-rich lipoprotein particle" BROAD [GOC:mah] +is_a: GO:0034358 ! plasma lipoprotein particle + +[Term] +id: GO:0034386 +name: 4-aminobutyrate:2-oxoglutarate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate." [EC:2.6.1.19, GOC:mah] +synonym: "4-aminobutanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "4-aminobutyrate-2-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "4-aminobutyrate-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "4-aminobutyrate-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-alpha-ketoglutaric acid transaminase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-alpha-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "GABA-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyrate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyric acid-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] +synonym: "gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity" EXACT [EC:2.6.1.19] +xref: EC:2.6.1.19 +xref: MetaCyc:GABATRANSAM-RXN +is_a: GO:0003867 ! 4-aminobutyrate transaminase activity + +[Term] +id: GO:0034387 +name: 4-aminobutyrate:pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine." [EC:2.6.1.96, GOC:mah] +synonym: "gamma-aminobutyric acid pyruvate transaminase activity" EXACT [EC:2.6.1.96] +xref: EC:2.6.1.96 +xref: MetaCyc:RXN-6902 +is_a: GO:0003867 ! 4-aminobutyrate transaminase activity + +[Term] +id: GO:0034388 +name: Pwp2p-containing subcomplex of 90S preribosome +namespace: cellular_component +def: "A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p." [GOC:krc, PMID:15231838] +comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +synonym: "25-30 S subcomplex of 90S preribosome" EXACT [] +synonym: "UTP-B complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0030686 ! 90S preribosome + +[Term] +id: GO:0034389 +name: lipid droplet organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle." [GOC:dph, GOC:jl, GOC:mah, PMID:18093937, PMID:18250201] +synonym: "adiposome organization" EXACT [] +synonym: "lipid body organization" EXACT [] +synonym: "lipid particle organisation" EXACT [] +synonym: "lipid particle organization" EXACT [] +synonym: "lipid particle organization and biogenesis" BROAD [GOC:mah] +is_a: GO:0006996 ! organelle organization +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13534 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15963 xsd:anyURI + +[Term] +id: GO:0034390 +name: smooth muscle cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] +synonym: "apoptosis of smooth muscle cells" EXACT [] +synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT [] +synonym: "programmed cell death, smooth muscle cells" EXACT [] +synonym: "SMC apoptosis" EXACT [] +synonym: "smooth muscle cell apoptosis" NARROW [] +synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT [] +is_a: GO:0010657 ! muscle cell apoptotic process + +[Term] +id: GO:0034391 +name: regulation of smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] +synonym: "regulation of SMC apoptosis" EXACT [] +synonym: "regulation of smooth muscle cell apoptosis" NARROW [] +is_a: GO:0010660 ! regulation of muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034390 ! smooth muscle cell apoptotic process +relationship: regulates GO:0034390 ! smooth muscle cell apoptotic process + +[Term] +id: GO:0034392 +name: negative regulation of smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] +synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] +synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] +synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] +synonym: "inhibition of smooth muscle cell apoptosis" NARROW [] +synonym: "negative regulation of SMC apoptosis" EXACT [] +synonym: "negative regulation of smooth muscle cell apoptosis" NARROW [] +is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process +is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process +relationship: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process + +[Term] +id: GO:0034393 +name: positive regulation of smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] +synonym: "activation of smooth muscle cell apoptosis" NARROW [] +synonym: "positive regulation of SMC apoptosis" EXACT [] +synonym: "positive regulation of smooth muscle cell apoptosis" NARROW [] +synonym: "stimulation of smooth muscle cell apoptosis" NARROW [] +synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] +synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] +synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] +is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process +is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process +relationship: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process + +[Term] +id: GO:0034394 +name: protein localization to cell surface +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane." [GOC:mah] +synonym: "protein localisation at cell surface" EXACT [GOC:mah] +synonym: "protein localization at cell surface" EXACT [] +is_a: GO:0034613 ! cellular protein localization + +[Term] +id: GO:0034395 +name: regulation of transcription from RNA polymerase II promoter in response to iron +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus." [GO_REF:0000021, GOC:mah] +synonym: "regulation of specific transcription from RNA polymerase II promoter in response to iron" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +relationship: part_of GO:0071281 ! cellular response to iron ion + +[Term] +id: GO:0034396 +name: negative regulation of transcription from RNA polymerase II promoter in response to iron +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus." [GOC:mah] +synonym: "down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] +synonym: "downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] +synonym: "inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [] +synonym: "negative regulation of transcription from Pol II promoter in response to iron" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0034395 ! regulation of transcription from RNA polymerase II promoter in response to iron + +[Term] +id: GO:0034397 +name: telomere localization +namespace: biological_process +def: "Any process in which a telomere is transported to, and/or maintained in, a specific location." [GOC:mah, GOC:vw] +synonym: "telomere localisation" EXACT [GOC:mah] +is_a: GO:0050000 ! chromosome localization + +[Term] +id: GO:0034398 +name: telomere tethering at nuclear periphery +namespace: biological_process +def: "The process in which a telomere is maintained in a specific location at the nuclear periphery." [GOC:mah] +is_a: GO:0034397 ! telomere localization + +[Term] +id: GO:0034399 +name: nuclear periphery +namespace: cellular_component +def: "The portion of the nuclear lumen proximal to the inner nuclear membrane." [GOC:krc, GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031981 ! nuclear lumen + +[Term] +id: GO:0034400 +name: gerontoplast +namespace: cellular_component +def: "A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence." [PMID:12654863, PMID:16151876] +is_a: GO:0009536 ! plastid + +[Term] +id: GO:0034401 +name: chromatin organization involved in regulation of transcription +namespace: biological_process +alt_id: GO:1903756 +alt_id: GO:1903757 +def: "Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription." [GOC:curators, PMID:21102443] +synonym: "activation of global transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "establishment or maintenance of chromatin architecture during transcription" EXACT [GOC:mah] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter by histone modification" NARROW [] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global by histone modification" NARROW [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "regulation of transcription by chromatin organisation" EXACT [GOC:mah] +synonym: "regulation of transcription by chromatin organization" EXACT [] +synonym: "regulation of transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter by histone modification" NARROW [] +synonym: "regulation of transcription from RNA polymerase II promoter, global by histone modification" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +is_a: GO:0006325 ! chromatin organization +intersection_of: GO:0006325 ! chromatin organization +intersection_of: part_of GO:0006355 ! regulation of transcription, DNA-templated +relationship: part_of GO:0006355 ! regulation of transcription, DNA-templated +created_by: rl +creation_date: 2014-12-18T14:56:16Z + +[Term] +id: GO:0034402 +name: recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex +namespace: biological_process +def: "The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript." [PMID:18195044] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0031124 ! mRNA 3'-end processing + +[Term] +id: GO:0034403 +name: alignment of 3' and 5' splice sites of mRNA +namespace: biological_process +def: "Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur." [GOC:krc, PMID:9430647] +synonym: "alignment of 3' and 5' splice sites of nuclear mRNA" EXACT [GOC:vw] +is_a: GO:0000389 ! mRNA 3'-splice site recognition +is_a: GO:0000395 ! mRNA 5'-splice site recognition +relationship: part_of GO:0000350 ! generation of catalytic spliceosome for second transesterification step + +[Term] +id: GO:0034404 +name: nucleobase-containing small molecule biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:mah] +synonym: "nucleobase, nucleoside and nucleotide anabolism" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide biosynthesis" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide formation" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide synthesis" EXACT [] +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process + +[Term] +id: GO:0034405 +name: response to fluid shear stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface." [GOC:sl] +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0034406 +name: cell wall beta-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall beta-glucan metabolism" EXACT [] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0034407 +name: cell wall (1->3)-beta-D-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall 1,3-beta-D-glucan metabolic process" EXACT [] +synonym: "cell wall 1,3-beta-glucan metabolic process" BROAD [] +synonym: "cell wall 1,3-beta-glucan metabolism" EXACT [] +synonym: "cell wall beta-1,3 glucan metabolic process" EXACT [] +synonym: "cell wall beta-1,3 glucan metabolism" EXACT [] +is_a: GO:0006074 ! (1->3)-beta-D-glucan metabolic process +is_a: GO:0034406 ! cell wall beta-glucan metabolic process + +[Term] +id: GO:0034408 +name: ascospore wall beta-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall beta-glucan metabolism" EXACT [] +is_a: GO:0070879 ! fungal-type cell wall beta-glucan metabolic process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0070591 ! ascospore wall biogenesis + +[Term] +id: GO:0034409 +name: ascospore wall (1->3)-beta-D-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall 1,3-beta-D-glucan metabolic process" EXACT [] +synonym: "ascospore wall 1,3-beta-glucan metabolic process" BROAD [] +synonym: "ascospore wall 1,3-beta-glucan metabolism" EXACT [GOC:mah] +synonym: "ascospore wall beta-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "ascospore wall beta-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0034408 ! ascospore wall beta-glucan metabolic process +is_a: GO:0071969 ! fungal-type cell wall (1->3)-beta-D-glucan metabolic process + +[Term] +id: GO:0034410 +name: cell wall beta-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall beta-glucan anabolism" EXACT [] +synonym: "cell wall beta-glucan biosynthesis" EXACT [] +synonym: "cell wall beta-glucan formation" EXACT [] +synonym: "cell wall beta-glucan synthesis" EXACT [] +is_a: GO:0034406 ! cell wall beta-glucan metabolic process +is_a: GO:0051274 ! beta-glucan biosynthetic process +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process + +[Term] +id: GO:0034411 +name: cell wall (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall 1,3-beta-D-glucan biosynthetic process" BROAD [] +synonym: "cell wall 1,3-beta-glucan anabolism" EXACT [] +synonym: "cell wall 1,3-beta-glucan biosynthesis" EXACT [] +synonym: "cell wall 1,3-beta-glucan biosynthetic process" BROAD [] +synonym: "cell wall 1,3-beta-glucan formation" EXACT [] +synonym: "cell wall 1,3-beta-glucan synthesis" EXACT [] +synonym: "cell wall beta-1,3-glucan anabolism" EXACT [] +synonym: "cell wall beta-1,3-glucan biosynthesis" EXACT [] +synonym: "cell wall beta-1,3-glucan biosynthetic process" EXACT [] +synonym: "cell wall beta-1,3-glucan formation" EXACT [] +synonym: "cell wall beta-1,3-glucan synthesis" EXACT [] +is_a: GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +is_a: GO:0034407 ! cell wall (1->3)-beta-D-glucan metabolic process +is_a: GO:0034410 ! cell wall beta-glucan biosynthetic process + +[Term] +id: GO:0034412 +name: ascospore wall beta-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall beta-glucan anabolism" EXACT [] +synonym: "ascospore wall beta-glucan biosynthesis" EXACT [] +synonym: "ascospore wall beta-glucan formation" EXACT [] +synonym: "ascospore wall beta-glucan synthesis" EXACT [] +is_a: GO:0034408 ! ascospore wall beta-glucan metabolic process +is_a: GO:0070880 ! fungal-type cell wall beta-glucan biosynthetic process + +[Term] +id: GO:0034413 +name: ascospore wall (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD [] +synonym: "ascospore wall 1,3-beta-glucan anabolism" EXACT [] +synonym: "ascospore wall 1,3-beta-glucan biosynthesis" EXACT [] +synonym: "ascospore wall 1,3-beta-glucan biosynthetic process" BROAD [] +synonym: "ascospore wall 1,3-beta-glucan formation" EXACT [] +synonym: "ascospore wall 1,3-beta-glucan synthesis" EXACT [] +synonym: "ascospore wall beta-1,3-glucan anabolism" EXACT [] +synonym: "ascospore wall beta-1,3-glucan biosynthesis" EXACT [] +synonym: "ascospore wall beta-1,3-glucan biosynthetic process" EXACT [] +synonym: "ascospore wall beta-1,3-glucan formation" EXACT [] +synonym: "ascospore wall beta-1,3-glucan synthesis" EXACT [] +is_a: GO:0034409 ! ascospore wall (1->3)-beta-D-glucan metabolic process +is_a: GO:0034412 ! ascospore wall beta-glucan biosynthetic process +is_a: GO:0071970 ! fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process + +[Term] +id: GO:0034414 +name: tRNA 3'-trailer cleavage, endonucleolytic +namespace: biological_process +def: "Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA." [GOC:mah] +synonym: "endonucleolytic tRNA 3'-end cleavage" EXACT [] +synonym: "endonucleolytic tRNA 3'-trailer cleavage" RELATED [] +synonym: "tRNA 3'-end cleavage, endonucleolytic" EXACT [] +is_a: GO:0042779 ! tRNA 3'-trailer cleavage +is_a: GO:1905267 ! endonucleolytic cleavage involved in tRNA processing + +[Term] +id: GO:0034415 +name: tRNA 3'-trailer cleavage, exonucleolytic +namespace: biological_process +def: "Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA." [GOC:mah] +synonym: "exonucleolytic tRNA 3'-end cleavage" EXACT [] +synonym: "exonucleolytic tRNA 3'-trailer cleavage" EXACT [] +synonym: "tRNA 3'-end cleavage, exonucleolytic" EXACT [] +is_a: GO:0042779 ! tRNA 3'-trailer cleavage +is_a: GO:0090503 ! RNA phosphodiester bond hydrolysis, exonucleolytic + +[Term] +id: GO:0034416 +name: bisphosphoglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate." [EC:3.1.3.80, GOC:mah, PMID:18413611] +synonym: "2,3-bisphosphoglycerate phosphatase activity" EXACT [] +synonym: "2,3-diphosphoglycerate phosphatase activity" EXACT [] +synonym: "2,3-diphosphoglyceric acid phosphatase activity" EXACT [] +synonym: "diphosphoglycerate phosphatase activity" EXACT [] +synonym: "glycerate-2,3-diphosphate phosphatase activity" EXACT [] +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0034417 +name: bisphosphoglycerate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate." [EC:3.1.3.80, GOC:mah, PMID:18413611] +synonym: "2,3-bisphospho-D-glycerate 3-phosphohydrolase activity" EXACT [EC:3.1.3.80] +xref: EC:3.1.3.80 +xref: KEGG_REACTION:R09532 +xref: MetaCyc:RXN-11102 +xref: RHEA:27381 +is_a: GO:0034416 ! bisphosphoglycerate phosphatase activity + +[Term] +id: GO:0034418 +name: urate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine." [GOC:mah] +synonym: "urate anabolism" RELATED [] +synonym: "urate biosynthesis" EXACT [] +synonym: "urate formation" EXACT [] +synonym: "urate synthesis" EXACT [] +synonym: "uric acid biosynthetic process" EXACT [] +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:0046415 ! urate metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0034419 +name: L-2-hydroxyglutarate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide." [PMID:18390652] +is_a: GO:0003973 ! (S)-2-hydroxy-acid oxidase activity + +[Term] +id: GO:0034420 +name: co-translational protein acetylation +namespace: biological_process +def: "The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome." [GOC:mah] +synonym: "co-translational protein amino acid acetylation" EXACT [GOC:bf] +synonym: "cotranslational protein amino acid acetylation" EXACT [] +is_a: GO:0006473 ! protein acetylation +is_a: GO:0043686 ! co-translational protein modification + +[Term] +id: GO:0034421 +name: post-translational protein acetylation +namespace: biological_process +def: "The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome." [GOC:mah] +synonym: "post-translational protein amino acid acetylation" EXACT [GOC:bf] +synonym: "posttranslational protein amino acid acetylation" EXACT [] +is_a: GO:0006473 ! protein acetylation +is_a: GO:0043687 ! post-translational protein modification + +[Term] +id: GO:0034422 +name: aleurone grain lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an aleurone grain." [GOC:rph] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0033095 ! aleurone grain + +[Term] +id: GO:0034423 +name: autophagosome lumen +namespace: cellular_component +def: "The volume enclosed within the autophagosome double-membrane." [GOC:autophagy, GOC:rph] +comment: Note that this term should be used for annotating gene products with caution: it should be used only to annotate gene products demonstrated to reside and function normally in the autophagic vacuole lumen, not for molecules that are temporarily found in the lumen prior to degradation. +synonym: "autophagic vacuole lumen" EXACT [GOC:autophagy] +is_a: GO:0005775 ! vacuolar lumen +relationship: part_of GO:0005776 ! autophagosome + +[Term] +id: GO:0034424 +name: Vps55/Vps68 complex +namespace: cellular_component +def: "A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins." [PMID:18216282] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0034425 +name: etioplast envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] +is_a: GO:0009526 ! plastid envelope +relationship: part_of GO:0009513 ! etioplast + +[Term] +id: GO:0034426 +name: etioplast membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround a etioplast and form the etioplast envelope." [GOC:rph] +is_a: GO:0042170 ! plastid membrane +relationship: part_of GO:0034425 ! etioplast envelope + +[Term] +id: GO:0034427 +name: nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction." [GOC:krc, GOC:mah] +synonym: "3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process" EXACT [] +is_a: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic + +[Term] +id: GO:0034428 +name: nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction." [GOC:krc, GOC:mah] +synonym: "5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process" EXACT [] +is_a: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic + +[Term] +id: GO:0034429 +name: tectobulbar tract morphogenesis +namespace: biological_process +def: "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain." [GOC:dsf, PMID:15065115, PMID:17507550, PMID:8038988] +is_a: GO:0021952 ! central nervous system projection neuron axonogenesis + +[Term] +id: GO:0034430 +name: monolayer-surrounded lipid storage body outer lipid monolayer +namespace: cellular_component +def: "The single layer of phopholipids surrounding a lipid storage body." [GOC:rph] +synonym: "lipid droplet outer lipid monolayer" RELATED [] +synonym: "lipid storage body surface lipid monolayer" EXACT [] +synonym: "oil body outer lipid monolayer" EXACT [] +synonym: "oleosome outer lipid monolayer" EXACT [] +synonym: "spherosome outer lipid monolayer" EXACT [] +is_a: GO:0034646 ! organelle-enclosing lipid monolayer +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0012511 ! monolayer-surrounded lipid storage body + +[Term] +id: GO:0034431 +name: bis(5'-adenosyl)-hexaphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate." [PMID:10085096, PMID:9450008] +synonym: "AP(6)A hydrolase activity" EXACT [] +synonym: "AP-6-A hydrolase activity" EXACT [] +synonym: "AP6A hydrolase activity" EXACT [] +synonym: "diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity" EXACT [] +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0034432 +name: bis(5'-adenosyl)-pentaphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate." [PMID:10085096, PMID:9450008] +synonym: "AP(5)A hydrolase activity" EXACT [] +synonym: "AP-5-A hydrolase activity" EXACT [] +synonym: "AP5A hydrolase activity" EXACT [] +synonym: "Ap5a pyrophosphohydrolase activity" EXACT [GOC:tb] +synonym: "diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity" EXACT [] +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0034433 +name: steroid esterification +namespace: biological_process +def: "A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol)." [GOC:BHF, GOC:mah, GOC:pde, GOC:rl] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0030258 ! lipid modification + +[Term] +id: GO:0034434 +name: sterol esterification +namespace: biological_process +def: "A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol)." [GOC:BHF, GOC:mah, GOC:pde, GOC:rl] +is_a: GO:0034433 ! steroid esterification + +[Term] +id: GO:0034435 +name: cholesterol esterification +namespace: biological_process +def: "A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle." [GOC:BHF, GOC:mah, GOC:pde, GOC:rl] +is_a: GO:0034434 ! sterol esterification + +[Term] +id: GO:0034436 +name: glycoprotein transport +namespace: biological_process +def: "The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] +is_a: GO:0015031 ! protein transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0034437 +name: obsolete glycoprotein transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a glycoprotein from one side of a membrane to the other." [GOC:BHF, GOC:mah, GOC:rl] +comment: This term was obsoleted because there is no transmembrane transporter specific for glycoproteins. +synonym: "glycoprotein transporter activity" RELATED [] +xref: Reactome:R-HSA-1022127 "OS9:SEL1:ERAD E3 ligase:DERL2 transports Ub-unfolded protein:(GlcNAc)2 (Man)9-5 from ERQC to cytosol" +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17130 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0034438 +name: lipoprotein amino acid oxidation +namespace: biological_process +def: "The modification of a lipoprotein by oxidation of one or more amino acids in the protein." [GOC:BHF, GOC:mah] +is_a: GO:0018158 ! protein oxidation +is_a: GO:0042161 ! lipoprotein oxidation + +[Term] +id: GO:0034439 +name: lipoprotein lipid oxidation +namespace: biological_process +def: "The modification of a lipoprotein by oxidation of the lipid group." [GOC:BHF, GOC:mah] +is_a: GO:0034440 ! lipid oxidation +is_a: GO:0042161 ! lipoprotein oxidation + +[Term] +id: GO:0034440 +name: lipid oxidation +namespace: biological_process +def: "The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen." [GOC:BHF, GOC:mah] +is_a: GO:0030258 ! lipid modification +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0034441 +name: plasma lipoprotein particle oxidation +namespace: biological_process +def: "The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids." [GOC:BHF, GOC:mah] +synonym: "plasma lipoprotein oxidation" RELATED [GOC:dph] +is_a: GO:0034369 ! plasma lipoprotein particle remodeling + +[Term] +id: GO:0034442 +name: regulation of lipoprotein oxidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipoprotein oxidation." [GOC:BHF, GOC:mah] +is_a: GO:0050746 ! regulation of lipoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042161 ! lipoprotein oxidation +relationship: regulates GO:0042161 ! lipoprotein oxidation + +[Term] +id: GO:0034443 +name: negative regulation of lipoprotein oxidation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation." [GOC:BHF, GOC:mah] +synonym: "inhibition of lipoprotein oxidation" NARROW [] +is_a: GO:0034442 ! regulation of lipoprotein oxidation +is_a: GO:0050748 ! negative regulation of lipoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042161 ! lipoprotein oxidation +relationship: negatively_regulates GO:0042161 ! lipoprotein oxidation + +[Term] +id: GO:0034444 +name: regulation of plasma lipoprotein oxidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma." [GOC:BHF, GOC:mah] +synonym: "regulation of plasma lipoprotein particle oxidation" RELATED [GOC:dph] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034441 ! plasma lipoprotein particle oxidation +relationship: regulates GO:0034441 ! plasma lipoprotein particle oxidation + +[Term] +id: GO:0034445 +name: negative regulation of plasma lipoprotein oxidation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma." [GOC:BHF, GOC:mah] +synonym: "inhibition of plasma lipoprotein oxidation" NARROW [] +synonym: "negative regulation of plasma lipoprotein particle oxidation" RELATED [GOC:dph] +is_a: GO:0034444 ! regulation of plasma lipoprotein oxidation +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034441 ! plasma lipoprotein particle oxidation +relationship: negatively_regulates GO:0034441 ! plasma lipoprotein particle oxidation + +[Term] +id: GO:0034446 +name: substrate adhesion-dependent cell spreading +namespace: biological_process +def: "The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate." [GOC:mah, GOC:pf, PMID:17050732] +synonym: "cell spreading during cell substrate adhesion" EXACT [] +synonym: "substrate adhesion dependent cell spreading" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0031589 ! cell-substrate adhesion + +[Term] +id: GO:0034447 +name: very-low-density lipoprotein particle clearance +namespace: biological_process +def: "The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF, GOC:rl] +synonym: "VLDL clearance" EXACT [] +is_a: GO:0034381 ! plasma lipoprotein particle clearance + +[Term] +id: GO:0034448 +name: EGO complex +namespace: cellular_component +alt_id: GO:0034449 +def: "A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p." [GOC:dgf, GOC:rb, PMID:15989961, PMID:16732272, PMID:19748353] +synonym: "EGO-GSE complex" EXACT [] +synonym: "GSE complex" EXACT [] +synonym: "GTPase-containing complex for Gap1p sorting in the endosome" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005768 ! endosome +relationship: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0034450 +name: ubiquitin-ubiquitin ligase activity +namespace: molecular_function +def: "Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue." [GOC:mah, GOC:mcc, PMID:10089879, PMID:17190603] +synonym: "E4" EXACT [] +xref: Reactome:R-HSA-937050 "Pellino ubiquitinates hp-IRAK1" +xref: Reactome:R-HSA-975122 "Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
" +is_a: GO:0061630 ! ubiquitin protein ligase activity + +[Term] +id: GO:0034451 +name: centriolar satellite +namespace: cellular_component +def: "A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome." [GOC:BHF, PMID:10579718, PMID:12403812] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005813 ! centrosome + +[Term] +id: GO:0034452 +name: dynactin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity." [GOC:BHF, GOC:mah] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0034453 +name: microtubule anchoring +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location in a cell." [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0034454 +name: microtubule anchoring at centrosome +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome." [GOC:BHF, GOC:mah] +is_a: GO:0072393 ! microtubule anchoring at microtubule organizing center + +[Term] +id: GO:0034455 +name: t-UTP complex +namespace: cellular_component +def: "A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p." [GOC:krc, GOC:mah, GOC:vw, PMID:17515605] +comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +synonym: "Nan1p-containing subcomplex of 90S preribosome" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005730 ! nucleolus + +[Term] +id: GO:0034456 +name: UTP-C complex +namespace: cellular_component +def: "A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p." [GOC:mah, PMID:17515605] +comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +synonym: "Rrp7p-containing subcomplex of 90S preribosome" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0030686 ! 90S preribosome + +[Term] +id: GO:0034457 +name: Mpp10 complex +namespace: cellular_component +def: "A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p." [GOC:mah, PMID:17515605] +comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0030686 ! 90S preribosome + +[Term] +id: GO:0034458 +name: 3'-5' RNA helicase activity +namespace: molecular_function +alt_id: GO:0034459 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'." [GOC:jp] +synonym: "3' to 5' RNA helicase activity" EXACT [] +synonym: "ATP-dependent 3' to 5' RNA helicase activity" EXACT [] +synonym: "ATP-dependent 3'-5' RNA helicase activity" EXACT [] +is_a: GO:0003724 ! RNA helicase activity + +[Term] +id: GO:0034460 +name: uropod assembly +namespace: biological_process +def: "The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane." [GOC:mah] +synonym: "uropod formation" EXACT [GOC:mah] +is_a: GO:0032796 ! uropod organization +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0034461 +name: uropod retraction +namespace: biological_process +def: "The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell." [GOC:mah, PMID:10704379] +is_a: GO:0032796 ! uropod organization + +[Term] +id: GO:0034462 +name: small-subunit processome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome." [GOC:mah] +synonym: "small subunit processome assembly" EXACT [] +synonym: "SSU processome assembly" EXACT [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000028 ! ribosomal small subunit assembly + +[Term] +id: GO:0034463 +name: 90S preribosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions." [GOC:krc, GOC:mah, GOC:tb] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0000027 ! ribosomal large subunit assembly +relationship: part_of GO:0000028 ! ribosomal small subunit assembly + +[Term] +id: GO:0034464 +name: BBSome +namespace: cellular_component +def: "A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B." [GOC:BHF, GOC:cilia, PMID:15231740, PMID:17574030, PMID:26498262] +synonym: "Bardet-Biedl syndrome complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005929 ! cilium + +[Term] +id: GO:0034465 +name: response to carbon monoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus." [GOC:ecd] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010033 ! response to organic substance +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0034466 +name: chromaffin granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a chromaffin granule." [GOC:rph] +is_a: GO:0034774 ! secretory granule lumen +relationship: part_of GO:0042583 ! chromaffin granule + +[Term] +id: GO:0034467 +name: esterosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an esterosome." [GOC:rph] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0033117 ! esterosome + +[Term] +id: GO:0034468 +name: glycosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a glycosome." [GOC:rph] +is_a: GO:0005782 ! peroxisomal matrix +relationship: part_of GO:0020015 ! glycosome + +[Term] +id: GO:0034469 +name: Golgi stack lumen +namespace: cellular_component +def: "The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex." [GOC:mah] +is_a: GO:0005796 ! Golgi lumen +relationship: part_of GO:0005795 ! Golgi stack + +[Term] +id: GO:0034470 +name: ncRNA processing +namespace: biological_process +def: "Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules." [GOC:mah] +is_a: GO:0006396 ! RNA processing +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0034471 +name: ncRNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of a non-coding RNA molecule." [GOC:mah] +synonym: "ncRNA 5' end processing" EXACT [] +is_a: GO:0000966 ! RNA 5'-end processing +is_a: GO:0034470 ! ncRNA processing + +[Term] +id: GO:0034472 +name: snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an snRNA molecule." [GOC:mah] +synonym: "snRNA 3' end processing" EXACT [] +is_a: GO:0016180 ! snRNA processing +is_a: GO:0043628 ! ncRNA 3'-end processing + +[Term] +id: GO:0034473 +name: U1 snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a U1 snRNA molecule." [GOC:mah] +synonym: "U1 snRNA 3' end processing" EXACT [] +is_a: GO:0034472 ! snRNA 3'-end processing + +[Term] +id: GO:0034474 +name: U2 snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a U2 snRNA molecule." [GOC:mah] +synonym: "U2 snRNA 3' end processing" EXACT [] +is_a: GO:0034472 ! snRNA 3'-end processing + +[Term] +id: GO:0034475 +name: U4 snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a U4 snRNA molecule." [GOC:mah] +synonym: "U4 snRNA 3' end processing" EXACT [] +is_a: GO:0034472 ! snRNA 3'-end processing + +[Term] +id: GO:0034476 +name: U5 snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a U5 snRNA molecule." [GOC:mah] +synonym: "U5 snRNA 3' end processing" EXACT [] +is_a: GO:0034472 ! snRNA 3'-end processing + +[Term] +id: GO:0034477 +name: U6 snRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a U6 snRNA molecule." [GOC:mah] +synonym: "U6 snRNA 3' end processing" EXACT [] +is_a: GO:0034472 ! snRNA 3'-end processing + +[Term] +id: GO:0034478 +name: phosphatidylglycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol." [GOC:mah] +synonym: "phosphatidylglycerol breakdown" EXACT [] +synonym: "phosphatidylglycerol catabolism" EXACT [] +synonym: "phosphatidylglycerol degradation" EXACT [] +is_a: GO:0046471 ! phosphatidylglycerol metabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process + +[Term] +id: GO:0034479 +name: phosphatidylglycerol phospholipase C activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate." [GOC:mah, PMID:18434318] +is_a: GO:0004629 ! phospholipase C activity + +[Term] +id: GO:0034480 +name: phosphatidylcholine phospholipase C activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate." [EC:3.1.4.3, GOC:mah] +synonym: "alpha-toxin" NARROW [EC:3.1.4.3] +synonym: "Clostridium oedematiens beta- and gamma-toxins activity" NARROW [EC:3.1.4.3] +synonym: "Clostridium welchii alpha-toxin activity" NARROW [EC:3.1.4.3] +synonym: "heat-labile hemolysin" NARROW [EC:3.1.4.3] +synonym: "lipophosphodiesterase I activity" EXACT [EC:3.1.4.3] +synonym: "phosphatidylcholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.3] +synonym: "phospholipase C, acting on phosphatidylcholine" EXACT [] +xref: EC:3.1.4.3 +xref: MetaCyc:PHOSPHOLIPASE-C-RXN +xref: RHEA:10604 +is_a: GO:0004629 ! phospholipase C activity + +[Term] +id: GO:0034481 +name: chondroitin sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate." [EC:2.8.2.17, EC:2.8.2.5, GOC:mah] +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0034482 +name: chondroitin 2-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues." [PMID:17227754] +synonym: "chondroitin 2-O-sulphotransferase activity" EXACT [] +synonym: "chondroitin 2-sulfotransferase activity" EXACT [] +is_a: GO:0034481 ! chondroitin sulfotransferase activity + +[Term] +id: GO:0034483 +name: heparan sulfate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate." [GOC:mah] +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0034484 +name: raffinose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside." [GOC:mah] +synonym: "raffinose breakdown" EXACT [] +synonym: "raffinose catabolism" EXACT [] +synonym: "raffinose degradation" EXACT [] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:0033530 ! raffinose metabolic process + +[Term] +id: GO:0034485 +name: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate." [GOC:pf] +xref: MetaCyc:RXN-10036 +xref: Reactome:R-HSA-1675949 "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane" +is_a: GO:0034594 ! phosphatidylinositol trisphosphate phosphatase activity +is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity + +[Term] +id: GO:0034486 +name: vacuolar transmembrane transport +namespace: biological_process +def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "vacuolar membrane transport" EXACT [] +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034487 +name: vacuolar amino acid transmembrane transport +namespace: biological_process +def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "vacuolar amino acid membrane transport" EXACT [] +is_a: GO:0003333 ! amino acid transmembrane transport + +[Term] +id: GO:0034488 +name: basic amino acid transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane." [GOC:mah] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0034487 ! vacuolar amino acid transmembrane transport +is_a: GO:1990822 ! basic amino acid transmembrane transport + +[Term] +id: GO:0034489 +name: neutral amino acid transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane." [GOC:mah] +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0032974 ! amino acid transmembrane export from vacuole + +[Term] +id: GO:0034490 +name: basic amino acid transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of basic amino acids into the vacuole across the vacuolar membrane." [GOC:mah] +is_a: GO:0032975 ! amino acid transmembrane import into vacuole +is_a: GO:1990822 ! basic amino acid transmembrane transport + +[Term] +id: GO:0034491 +name: neutral amino acid transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of neutral amino acids into the vacuole across the vacuolar membrane." [GOC:mah] +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0032975 ! amino acid transmembrane import into vacuole + +[Term] +id: GO:0034492 +name: hydrogenosome lumen +namespace: cellular_component +def: "The volume enclosed by the hydrogenosome membrane." [GOC:rph] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0042566 ! hydrogenosome + +[Term] +id: GO:0034493 +name: melanosome lumen +namespace: cellular_component +def: "The volume enclosed by the melanosome membrane." [GOC:rph] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0042470 ! melanosome + +[Term] +id: GO:0034494 +name: microneme lumen +namespace: cellular_component +def: "The volume enclosed by the microneme membrane." [GOC:rph] +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0020009 ! microneme + +[Term] +id: GO:0034495 +name: protein storage vacuole lumen +namespace: cellular_component +def: "The volume enclosed by the protein storage vacuole membrane." [GOC:rph] +is_a: GO:0000330 ! plant-type vacuole lumen +relationship: part_of GO:0000326 ! protein storage vacuole + +[Term] +id: GO:0034496 +name: multivesicular body membrane disassembly +namespace: biological_process +def: "The controlled breakdown of the membranes of multivesicular bodies." [GOC:rb] +synonym: "MVB membrane disassembly" EXACT [] +is_a: GO:0030397 ! membrane disassembly +relationship: part_of GO:0036257 ! multivesicular body organization + +[Term] +id: GO:0034497 +name: protein localization to phagophore assembly site +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS)." [GOC:rb] +synonym: "protein localisation to phagophore assembly site" EXACT [GOC:mah] +synonym: "protein localization to PAS" EXACT [] +synonym: "protein localization to pre-autophagosomal structure" NARROW [] +is_a: GO:0034613 ! cellular protein localization +relationship: part_of GO:0000045 ! autophagosome assembly + +[Term] +id: GO:0034498 +name: early endosome to Golgi transport +namespace: biological_process +def: "The directed movement of substances from early endosomes to the Golgi." [GOC:rb] +synonym: "PGE to Golgi transport" EXACT [] +synonym: "post-Golgi endosome to Golgi transport" EXACT [] +is_a: GO:0042147 ! retrograde transport, endosome to Golgi +is_a: GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0034499 +name: late endosome to Golgi transport +namespace: biological_process +def: "The directed movement of substances from late endosomes to the Golgi." [GOC:rb] +synonym: "prevacuolar endosome to Golgi transport" EXACT [] +synonym: "PVE to Golgi transport" EXACT [] +is_a: GO:0042147 ! retrograde transport, endosome to Golgi +is_a: GO:0048193 ! Golgi vesicle transport +relationship: occurs_in GO:0005737 ! cytoplasm + +[Term] +id: GO:0034501 +name: protein localization to kinetochore +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the kinetochore." [GOC:mah] +synonym: "condensin localization to kinetochore" NARROW [] +synonym: "protein localisation to kinetochore" EXACT [GOC:mah] +is_a: GO:0071459 ! protein localization to chromosome, centromeric region + +[Term] +id: GO:0034502 +name: protein localization to chromosome +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah] +synonym: "condensin localization to chromosome" NARROW [] +synonym: "protein localisation to chromosome" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle + +[Term] +id: GO:0034503 +name: protein localization to nucleolar rDNA repeats +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus." [GOC:mah] +synonym: "condensin localization to nucleolar rDNA repeats" NARROW [] +synonym: "protein localisation to nucleolar rDNA repeats" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome +relationship: part_of GO:0007000 ! nucleolus organization + +[Term] +id: GO:0034504 +name: protein localization to nucleus +namespace: biological_process +alt_id: GO:0044744 +def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd] +synonym: "protein localisation to nucleus" EXACT [GOC:mah] +synonym: "protein localization in cell nucleus" EXACT [] +synonym: "protein localization in nucleus" EXACT [GOC:mah] +synonym: "protein targeting to nucleus" RELATED [] +is_a: GO:0033365 ! protein localization to organelle +creation_date: 2012-11-07T15:45:54Z + +[Term] +id: GO:0034505 +name: tooth mineralization +namespace: biological_process +def: "The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum." [GOC:mah, MP:0002817, MSH:D014074] +synonym: "tooth calcification" EXACT [] +is_a: GO:0031214 ! biomineral tissue development +relationship: part_of GO:0042476 ! odontogenesis + +[Term] +id: GO:0034506 +name: chromosome, centromeric core domain +namespace: cellular_component +def: "The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it." [GOC:mah, GOC:vw] +synonym: "chromosome, centric core region" RELATED [] +synonym: "chromosome, centromeric core region" EXACT [GOC:vw] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0034507 +name: chromosome, centromeric outer repeat region +namespace: cellular_component +def: "The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it." [GOC:mah, GOC:vw] +synonym: "chromosome, centric outer repeat region" RELATED [] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0034508 +name: centromere complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere." [GOC:mah, GOC:vw] +synonym: "centromere assembly" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "centromere organization" EXACT [GOC:dph, PMID:18923422] +synonym: "chromosome, centromeric region assembly" EXACT [GOC:pr] +is_a: GO:0051276 ! chromosome organization +is_a: GO:0065004 ! protein-DNA complex assembly + +[Term] +id: GO:0034510 +name: centromere separation +namespace: biological_process +def: "The cell cycle process in which centromeres are physically detached from each other during chromosome separation." [GOC:mah] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0051304 ! chromosome separation +relationship: part_of GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0034511 +name: U3 snoRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with U3 small nucleolar RNA." [GOC:mah] +is_a: GO:0030515 ! snoRNA binding + +[Term] +id: GO:0034512 +name: box C/D snoRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with box C/D small nucleolar RNA." [GOC:mah] +is_a: GO:0030515 ! snoRNA binding + +[Term] +id: GO:0034513 +name: box H/ACA snoRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with box H/ACA small nucleolar RNA." [GOC:mah] +is_a: GO:0030515 ! snoRNA binding + +[Term] +id: GO:0034514 +name: mitochondrial unfolded protein response +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins." [GOC:mah, PMID:17849004] +synonym: "mtUPR" EXACT [] +is_a: GO:0034620 ! cellular response to unfolded protein + +[Term] +id: GO:0034515 +name: proteasome storage granule +namespace: cellular_component +def: "A multisubunit proteasome complex that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state." [GOC:rb, PMID:18504300] +synonym: "PSG" EXACT [] +is_a: GO:0031597 ! cytosolic proteasome complex + +[Term] +id: GO:0034516 +name: response to vitamin B6 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:mah, GOC:rph] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0034517 +name: ribophagy +namespace: biological_process +def: "The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation." [GOC:autophagy, PMID:18391941] +is_a: GO:0061912 ! selective autophagy +relationship: has_part GO:0032790 ! ribosome disassembly + +[Term] +id: GO:0034518 +name: RNA cap binding complex +namespace: cellular_component +def: "Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA." [GOC:mah] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0034519 +name: cytoplasmic RNA cap binding complex +namespace: cellular_component +def: "A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA." [PMID:16405910] +is_a: GO:0005845 ! mRNA cap binding complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0034520 +name: 2-naphthaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+." [UM-BBD_reactionID:r0772] +xref: EC:1.2.1 +xref: UM-BBD_reactionID:r0772 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0034521 +name: 1-naphthoic acid dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+." [UM-BBD_reactionID:r0773] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0773 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034522 +name: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-." [UM-BBD_reactionID:r0774] +xref: UM-BBD_reactionID:r0774 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034523 +name: 3-formylsalicylate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide." [UM-BBD_reactionID:r0777] +xref: UM-BBD_reactionID:r0777 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0034524 +name: 2-hydroxyisophthalate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2." [UM-BBD_reactionID:r0776] +xref: UM-BBD_reactionID:r0776 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034525 +name: 1-naphthaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+." [UM-BBD_reactionID:r0787] +xref: UM-BBD_reactionID:r0787 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034526 +name: 2-methylnaphthalene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O." [UM-BBD_reactionID:r0788] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0788 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034527 +name: 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene." [UM-BBD_reactionID:r0790] +xref: UM-BBD_reactionID:r0790 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0034528 +name: 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate." [UM-BBD_reactionID:r0791] +xref: EC:5.3.99 +xref: UM-BBD_reactionID:r0791 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0034529 +name: 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate." [UM-BBD_reactionID:r0792] +xref: EC:4.1.2 +xref: UM-BBD_reactionID:r0792 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0034530 +name: 4-hydroxymethylsalicyaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+." [UM-BBD_reactionID:r0767] +xref: EC:1.2.1 +xref: UM-BBD_reactionID:r0767 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0034531 +name: 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde." [UM-BBD_reactionID:r0766] +xref: EC:4.1.2 +xref: UM-BBD_reactionID:r0766 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0034532 +name: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate." [UM-BBD_reactionID:r0765] +xref: EC:5.3.99 +xref: UM-BBD_reactionID:r0765 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0034533 +name: 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate." [UM-BBD_reactionID:r0764] +xref: UM-BBD_reactionID:r0764 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0034534 +name: 1-methylnaphthalene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O." [UM-BBD_reactionID:r0795] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0795 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034535 +name: 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+." [UM-BBD_reactionID:r0781] +xref: UM-BBD_reactionID:r0781 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0034536 +name: 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate." [UM-BBD_reactionID:r0782] +xref: EC:5.3.99 +xref: UM-BBD_reactionID:r0782 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0034537 +name: 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde." [UM-BBD_reactionID:r0783] +xref: EC:4.1.2 +xref: UM-BBD_reactionID:r0783 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0034538 +name: 3-methylsalicylaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+." [UM-BBD_reactionID:r0784] +xref: UM-BBD_reactionID:r0784 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034539 +name: 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr." [UM-BBD_reactionID:r0821] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0821 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034540 +name: 3-monobromobisphenol A reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr." [UM-BBD_reactionID:r0824] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0824 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034541 +name: dimethylarsinite methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH." [UM-BBD_reactionID:r0806] +xref: UM-BBD_reactionID:r0806 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0034542 +name: trimethylarsine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O." [UM-BBD_reactionID:r0807] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0807 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034543 +name: 5-aminosalicylate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate." [UM-BBD_reactionID:r0809] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0809 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034544 +name: trans-ACOHDA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3." [UM-BBD_reactionID:r0810] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r0810 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034545 +name: fumarylpyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+." [UM-BBD_reactionID:r0811] +xref: EC:3.7.1.20 +xref: UM-BBD_reactionID:r0811 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034546 +name: 2,4-dichloroaniline reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl." [UM-BBD_reactionID:r0819] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0819 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034547 +name: N-cyclopropylmelamine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3." [UM-BBD_reactionID:r0825] +xref: MetaCyc:RXN-8018 +xref: UM-BBD_reactionID:r0825 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0034548 +name: N-cyclopropylammeline deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3." [UM-BBD_reactionID:r0826] +xref: MetaCyc:RXN-8019 +xref: UM-BBD_reactionID:r0826 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0034549 +name: N-cyclopropylammelide alkylamino hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid." [UM-BBD_reactionID:r0827] +xref: KEGG_REACTION:R06972 +xref: MetaCyc:RXN-8020 +xref: UM-BBD_reactionID:r0827 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0034550 +name: dimethylarsinate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O." [UM-BBD_reactionID:r0838] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0838 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034551 +name: mitochondrial respiratory chain complex III assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane." [GOC:dgf, GOC:mcc] +synonym: "mitochondrial cytochrome bc(1) complex assembly" EXACT [GOC:mcc] +is_a: GO:0017062 ! respiratory chain complex III assembly +is_a: GO:0033108 ! mitochondrial respiratory chain complex assembly +intersection_of: GO:0017062 ! respiratory chain complex III assembly +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0034552 +name: respiratory chain complex II assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II." [GOC:dgf] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0034553 +name: mitochondrial respiratory chain complex II assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane." [GOC:dgf] +is_a: GO:0033108 ! mitochondrial respiratory chain complex assembly +is_a: GO:0034552 ! respiratory chain complex II assembly +intersection_of: GO:0034552 ! respiratory chain complex II assembly +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0034554 +name: 3,3',5-tribromobisphenol A reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr." [UM-BBD_reactionID:r0842] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0842 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034555 +name: 3,3'-dibromobisphenol A reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr." [UM-BBD_reactionID:r0844] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0844 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034556 +name: nitrobenzoate nitroreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+." [UM-BBD_reactionID:r0849] +xref: EC:1.7.1 +xref: UM-BBD_reactionID:r0849 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0034557 +name: 2-hydroxylaminobenzoate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O." [MetaCyc:RXN-8848] +synonym: "o-hydroxylaminobenzoate nitroreductase activity" RELATED [UM-BBD_reactionID:r0850] +xref: MetaCyc:RXN-8848 +xref: UM-BBD_reactionID:r0850 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0034558 +name: technetium (VII) reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-." [UM-BBD_reactionID:r0859] +xref: UM-BBD_reactionID:r0859 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0034559 +name: bisphenol A hydroxylase B activity +namespace: molecular_function +def: "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0860] +xref: UM-BBD_reactionID:r0860 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034560 +name: bisphenol A hydroxylase A activity +namespace: molecular_function +def: "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0861] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r0861 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034561 +name: 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O." [UM-BBD_reactionID:r0862] +xref: UM-BBD_reactionID:r0862 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034562 +name: 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O." [UM-BBD_reactionID:r0864] +xref: UM-BBD_reactionID:r0864 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034563 +name: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-." [UM-BBD_reactionID:r0867] +xref: UM-BBD_reactionID:r0867 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034564 +name: 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-." [UM-BBD_reactionID:r0866] +xref: UM-BBD_reactionID:r0866 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034565 +name: 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol." [UM-BBD_reactionID:r0872] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r0872 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034567 +name: chromate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: chromate = chromium (III)." [UM-BBD_reactionID:r0884] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0884 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034568 +name: isoproturon dimethylaminedehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-." [UM-BBD_reactionID:r0892] +xref: EC:1.5.99 +xref: UM-BBD_reactionID:r0892 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0034569 +name: monodemethylisoproturon dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-." [UM-BBD_reactionID:r0893] +xref: EC:1.17.99 +xref: UM-BBD_reactionID:r0893 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0034570 +name: hydroxymonomethylisoproturon dimethylaminedehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0894] +xref: EC:1.5.99 +xref: UM-BBD_reactionID:r0894 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0034571 +name: 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid." [UM-BBD_reactionID:r0895] +xref: UM-BBD_reactionID:r0895 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034572 +name: monodemethylisoproturon dimethylaminedehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-." [UM-BBD_reactionID:r0897] +xref: EC:1.5.99 +xref: UM-BBD_reactionID:r0897 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0034573 +name: didemethylisoproturon amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline." [UM-BBD_reactionID:r0898] +xref: UM-BBD_reactionID:r0898 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034574 +name: didemethylisoproturon dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0899] +xref: EC:1.17.99 +xref: UM-BBD_reactionID:r0899 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0034575 +name: 4-isopropylaniline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-." [UM-BBD_reactionID:r0901] +xref: EC:1.17.99 +xref: UM-BBD_reactionID:r0901 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0034576 +name: N-isopropylacetanilide amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate." [UM-BBD_reactionID:r0913] +xref: UM-BBD_reactionID:r0913 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034577 +name: N-isopropylacetaniline monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone." [UM-BBD_reactionID:r0914] +xref: EC:1.14.15 +xref: UM-BBD_reactionID:r0914 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034578 +name: limonene 8-hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: limonene + H2O = alpha-terpineol." [UM-BBD_reactionID:r0916] +xref: UM-BBD_reactionID:r0916 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034579 +name: (1-methylpentyl)succinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate." [UM-BBD_reactionID:r0920] +xref: UM-BBD_reactionID:r0920 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0034580 +name: 4-methyloctanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0924] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r0924 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034581 +name: 4-methyloct-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA." [UM-BBD_reactionID:r0925] +xref: UM-BBD_reactionID:r0925 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034582 +name: 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0926] +xref: UM-BBD_reactionID:r0926 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034583 +name: 21U-RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0034584 +name: piRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv] +synonym: "Piwi-associated RNA binding" EXACT [] +is_a: GO:0061980 ! regulatory RNA binding + +[Term] +id: GO:0034585 +name: 21U-RNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv] +synonym: "21U-RNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0034586 +name: 21U-RNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv] +synonym: "21U-RNA breakdown" EXACT [] +synonym: "21U-RNA catabolism" EXACT [] +synonym: "21U-RNA degradation" EXACT [] +is_a: GO:0034585 ! 21U-RNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0034587 +name: piRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv] +subset: goslim_drosophila +synonym: "piRNA metabolism" EXACT [] +synonym: "Piwi-associated RNA metabolic process" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0034588 +name: piRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv] +synonym: "piRNA breakdown" EXACT [] +synonym: "piRNA catabolism" EXACT [] +synonym: "piRNA degradation" EXACT [] +synonym: "Piwi-associated RNA catabolic process" EXACT [] +is_a: GO:0034587 ! piRNA metabolic process +is_a: GO:0034661 ! ncRNA catabolic process + +[Term] +id: GO:0034589 +name: hydroxyproline transport +namespace: biological_process +def: "The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah, PMID:14502423] +synonym: "4-hydroxyproline transport" EXACT [] +synonym: "L-hydroxyproline transport" NARROW [] +is_a: GO:0006865 ! amino acid transport +is_a: GO:0072337 ! modified amino acid transport + +[Term] +id: GO:0034590 +name: L-hydroxyproline transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-hydroxyproline from one side of a membrane to the other." [GOC:mah, PMID:14502423] +synonym: "4-hydroxyproline transmembrane transporter activity" BROAD [] +xref: Reactome:R-HSA-6784213 "Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix" +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +relationship: part_of GO:0034589 ! hydroxyproline transport + +[Term] +id: GO:0034591 +name: rhoptry lumen +namespace: cellular_component +def: "The volume enclosed by the rhoptry membrane." [GOC:rph, PMID:17997128] +is_a: GO:0043233 ! organelle lumen +relationship: part_of GO:0020008 ! rhoptry + +[Term] +id: GO:0034592 +name: synaptic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the synaptic vesicle membrane." [GOC:rph] +subset: goslim_synapse +is_a: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0008021 ! synaptic vesicle +relationship: part_of GO:0008021 ! synaptic vesicle + +[Term] +id: GO:0034593 +name: phosphatidylinositol bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate." [GOC:mah] +synonym: "diphosphoinositide phosphatase activity" RELATED [] +synonym: "phosphatidyl-inositol-bisphosphate phosphatase activity" EXACT [] +synonym: "phosphatidylinositol-bisphosphatase activity" RELATED [] +synonym: "triphosphoinositide phosphatase activity" RELATED [] +synonym: "triphosphoinositide phosphomonoesterase activity" RELATED [] +is_a: GO:0052866 ! phosphatidylinositol phosphate phosphatase activity + +[Term] +id: GO:0034594 +name: phosphatidylinositol trisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate." [GOC:mah] +is_a: GO:0052866 ! phosphatidylinositol phosphate phosphatase activity + +[Term] +id: GO:0034595 +name: phosphatidylinositol phosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate." [GOC:elh] +synonym: "phosphoinositide 5-phosphatase activity" EXACT [] +synonym: "polyphosphoinositol lipid 5-phosphatase activity" EXACT [] +is_a: GO:0052866 ! phosphatidylinositol phosphate phosphatase activity + +[Term] +id: GO:0034596 +name: phosphatidylinositol phosphate 4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate." [GOC:mah] +synonym: "inositol 4-phosphatase" NARROW [GOC:rl] +synonym: "phosphoinositide 4-phosphatase activity" EXACT [] +synonym: "PI(4)P-phosphatase activity" EXACT [GOC:rl] +synonym: "PI4P-phosphatase activity" EXACT [GOC:rl] +synonym: "PtdIns4P-phosphatase activity" EXACT [GOC:rl] +xref: Reactome:R-HSA-1675988 "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane" +xref: Reactome:R-HSA-1676124 "PI4P is dephosphorylated to PI by SACM1L at the ER membrane" +xref: Reactome:R-HSA-1676133 "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane" +xref: Reactome:R-HSA-8849969 "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane" +is_a: GO:0052866 ! phosphatidylinositol phosphate phosphatase activity + +[Term] +id: GO:0034597 +name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate." [GOC:mah] +synonym: "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity" EXACT [] +synonym: "inositol polyphosphate 4-phosphatase type II activity" RELATED [EC:3.1.3.66] +synonym: "phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity" EXACT [] +xref: EC:3.1.3.66 +xref: MetaCyc:3.1.3.66-RXN +xref: Reactome:R-HSA-6810410 "PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus" +is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity +is_a: GO:0106019 ! phosphatidylinositol-4,5-bisphosphate phosphatase activity + +[Term] +id: GO:0034598 +name: phosphothreonine lyase activity +namespace: molecular_function +def: "Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product." [PMID:17303758, PMID:18084305] +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034599 +name: cellular response to oxidative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] +synonym: "adaptive response to oxidative stress" NARROW [GOC:add, GOC:vk] +is_a: GO:0006979 ! response to oxidative stress +is_a: GO:0062197 ! cellular response to chemical stress + +[Term] +id: GO:0034601 +name: oxoglutarate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H." [EC:1.2.1.52, GOC:mah] +xref: EC:1.2.1.52 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034602 +name: oxoglutarate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH." [GOC:mah] +xref: EC:1.2.1 +xref: KEGG_REACTION:R08549 +xref: MetaCyc:2OXOGLUTARATEDEH-RXN +xref: Reactome:R-HSA-71037 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+" +xref: Reactome:R-HSA-71401 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+" +is_a: GO:0034601 ! oxoglutarate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0034603 +name: pyruvate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H." [GOC:mah] +is_a: GO:0004738 ! pyruvate dehydrogenase activity +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034604 +name: pyruvate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH." [GOC:mah, ISBN:0201090910] +xref: KEGG_REACTION:R00209 +xref: MetaCyc:PYRUVDEH-RXN +xref: RHEA:28042 +is_a: GO:0034603 ! pyruvate dehydrogenase [NAD(P)+] activity +relationship: has_part GO:0004148 ! dihydrolipoyl dehydrogenase activity +relationship: has_part GO:0004739 ! pyruvate dehydrogenase (acetyl-transferring) activity +relationship: has_part GO:0004742 ! dihydrolipoyllysine-residue acetyltransferase activity +relationship: part_of GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate + +[Term] +id: GO:0034605 +name: cellular response to heat +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:mah] +synonym: "cellular response to heat stress" EXACT [] +is_a: GO:0009408 ! response to heat +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0034606 +name: response to hermaphrodite contact +namespace: biological_process +def: "The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." [PMID:18050467, WB_REF:WBPaper00002109] +is_a: GO:0060179 ! male mating behavior + +[Term] +id: GO:0034607 +name: turning behavior involved in mating +namespace: biological_process +def: "The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [PMID:18050467, WB_REF:WBPaper00002109] +synonym: "turning behavior during mating" EXACT [] +is_a: GO:0035178 ! turning behavior +is_a: GO:0060179 ! male mating behavior +intersection_of: GO:0035178 ! turning behavior +intersection_of: part_of GO:0007618 ! mating + +[Term] +id: GO:0034608 +name: vulval location +namespace: biological_process +def: "Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." [PMID:18050467] +is_a: GO:0060179 ! male mating behavior + +[Term] +id: GO:0034609 +name: spicule insertion +namespace: biological_process +def: "Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." [PMID:18050467] +is_a: GO:0060179 ! male mating behavior + +[Term] +id: GO:0034610 +name: oligodeoxyribonucleotidase activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates." [GOC:mah] +synonym: "DNA oligonucleotidase activity" EXACT [] +is_a: GO:0004536 ! deoxyribonuclease activity +is_a: GO:0008946 ! oligonucleotidase activity + +[Term] +id: GO:0034611 +name: oligoribonucleotidase activity +namespace: molecular_function +def: "Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates." [GOC:mah] +synonym: "RNA oligonucleotidase activity" EXACT [] +xref: Reactome:R-HSA-9009950 "PDE12 cleaves 2'-5' oligoadenylates" +xref: Reactome:R-HSA-9615042 "Viral 2',5'-PDE cleaves 2'-5' oligoadenylates" +is_a: GO:0004540 ! ribonuclease activity +is_a: GO:0008946 ! oligonucleotidase activity + +[Term] +id: GO:0034612 +name: response to tumor necrosis factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus." [GOC:mah] +synonym: "response to TNF" EXACT [] +is_a: GO:0034097 ! response to cytokine + +[Term] +id: GO:0034613 +name: cellular protein localization +namespace: biological_process +alt_id: GO:0016249 +def: "Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah] +subset: goslim_drosophila +synonym: "cellular protein localisation" EXACT [GOC:mah] +synonym: "channel localizer activity" NARROW [GOC:mah] +is_a: GO:0008104 ! protein localization +is_a: GO:0070727 ! cellular macromolecule localization + +[Term] +id: GO:0034614 +name: cellular response to reactive oxygen species +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:mah] +synonym: "cellular response to active oxygen species" EXACT [] +synonym: "cellular response to AOS" EXACT [] +synonym: "cellular response to reactive oxidative species" EXACT [] +synonym: "cellular response to reactive oxygen intermediate" EXACT [] +synonym: "cellular response to ROI" EXACT [] +synonym: "cellular response to ROS" EXACT [] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0034599 ! cellular response to oxidative stress +is_a: GO:1901701 ! cellular response to oxygen-containing compound + +[Term] +id: GO:0034615 +name: GCH1 complex +namespace: cellular_component +def: "A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive." [PMID:16696853] +synonym: "GTP cyclohydrolase I complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034616 +name: response to laminar fluid shear stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls." [GOC:ecd] +is_a: GO:0034405 ! response to fluid shear stress + +[Term] +id: GO:0034617 +name: tetrahydrobiopterin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions." [GOC:BHF, GOC:mah, GOC:rl] +synonym: "BH4 binding" EXACT [] +synonym: "H4biopterin binding" EXACT [] +synonym: "sapropterin binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0034618 +name: arginine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid." [GOC:BHF, GOC:rl] +synonym: "aminopentanoic acid binding" RELATED [] +synonym: "Arg binding" EXACT [] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0034620 +name: cellular response to unfolded protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." [GOC:mah] +comment: Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER. +synonym: "heat shock protein activity" RELATED [] +is_a: GO:0006986 ! response to unfolded protein +is_a: GO:0035967 ! cellular response to topologically incorrect protein + +[Term] +id: GO:0034622 +name: cellular protein-containing complex assembly +namespace: biological_process +alt_id: GO:0043623 +def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell." [GOC:jl] +synonym: "cellular macromolecule complex assembly" RELATED [] +synonym: "cellular protein complex assembly" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0034624 +name: DNA recombinase assembly involved in gene conversion at mating-type locus +namespace: biological_process +def: "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another." [GOC:mah] +is_a: GO:0000730 ! DNA recombinase assembly +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0000730 ! DNA recombinase assembly +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0034625 +name: fatty acid elongation, monounsaturated fatty acid +namespace: biological_process +def: "Elongation of a fatty acid chain into which one C-C double bond has been introduced." [GOC:mah] +is_a: GO:0019368 ! fatty acid elongation, unsaturated fatty acid + +[Term] +id: GO:0034626 +name: fatty acid elongation, polyunsaturated fatty acid +namespace: biological_process +def: "Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced." [GOC:mah] +is_a: GO:0019368 ! fatty acid elongation, unsaturated fatty acid + +[Term] +id: GO:0034627 +name: 'de novo' NAD biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:imk, PMID:17161604] +synonym: "de novo NAD biosynthetic process" RELATED [] +is_a: GO:0009435 ! NAD biosynthetic process + +[Term] +id: GO:0034628 +name: 'de novo' NAD biosynthetic process from aspartate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:imk] +synonym: "de novo NAD biosynthetic process from aspartate" RELATED [] +is_a: GO:0019355 ! nicotinamide nucleotide biosynthetic process from aspartate +is_a: GO:0034627 ! 'de novo' NAD biosynthetic process + +[Term] +id: GO:0034629 +name: cellular protein-containing complex localization +namespace: biological_process +def: "A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell." [GOC:mah] +synonym: "cellular protein complex localisation" EXACT [GOC:mah] +synonym: "cellular protein complex localization" RELATED [] +synonym: "establishment and maintenance of cellular protein complex localization" EXACT [] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0034613 ! cellular protein localization + +[Term] +id: GO:0034630 +name: RITS complex localization +namespace: biological_process +def: "Any process in which a RITS complex is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of RITS complex localization" EXACT [] +synonym: "RITS complex localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization + +[Term] +id: GO:0034631 +name: microtubule anchoring at spindle pole body +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end." [GOC:mah, PMID:17486116] +synonym: "attachment of spindle microtubules to SPB" EXACT [] +synonym: "attachment of spindle microtubules to spindle pole body" EXACT [] +synonym: "microtubule anchoring at SPB" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0072393 ! microtubule anchoring at microtubule organizing center +relationship: part_of GO:0007051 ! spindle organization + +[Term] +id: GO:0034632 +name: retinol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah, GOC:vk] +synonym: "retinol transporter activity" RELATED [] +synonym: "vitamin A1 transporter activity" EXACT [] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:0034633 ! retinol transport + +[Term] +id: GO:0034633 +name: retinol transport +namespace: biological_process +def: "The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah, GOC:vk] +synonym: "vitamin A1 transport" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0046865 ! terpenoid transport + +[Term] +id: GO:0034634 +name: glutathione transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other." [GOC:mah] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0042937 ! tripeptide transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0034775 ! glutathione transmembrane transport + +[Term] +id: GO:0034635 +name: glutathione transport +namespace: biological_process +def: "The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0042939 ! tripeptide transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0034636 +name: strand invasion involved in gene conversion at mating-type locus +namespace: biological_process +def: "The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA at the mating-type locus. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This process occurs as part of gene conversion at the mating-type locus." [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0042148 ! strand invasion +intersection_of: GO:0042148 ! strand invasion +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus + +[Term] +id: GO:0034637 +name: cellular carbohydrate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells." [GOC:mah] +is_a: GO:0016051 ! carbohydrate biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0034638 +name: phosphatidylcholine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:jp] +synonym: "phosphatidylcholine breakdown" EXACT [] +synonym: "phosphatidylcholine catabolism" EXACT [] +synonym: "phosphatidylcholine degradation" EXACT [] +is_a: GO:0046470 ! phosphatidylcholine metabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0034639 +name: L-amino acid efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane." [GOC:mah] +synonym: "L-amino acid efflux permease activity" EXACT [] +synonym: "L-amino acid export transporter activity" EXACT [] +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity + +[Term] +id: GO:0034640 +name: establishment of mitochondrion localization by microtubule attachment +namespace: biological_process +def: "The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization." [GOC:mah, PMID:12972644] +synonym: "establishment of mitochondrion localisation by microtubule attachment" EXACT [GOC:mah] +synonym: "mitochondrial localization by microtubule attachment" EXACT [] +synonym: "mitochondrial migration by microtubule attachment" EXACT [] +synonym: "mitochondrion migration by microtubule attachment" EXACT [] +is_a: GO:0034643 ! establishment of mitochondrion localization, microtubule-mediated +is_a: GO:0099098 ! microtubule polymerization based movement + +[Term] +id: GO:0034641 +name: cellular nitrogen compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "cellular nitrogen compound metabolism" EXACT [] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0034642 +name: mitochondrion migration along actin filament +namespace: biological_process +def: "The directed movement of a mitochondrion along a microfilament, mediated by motor proteins." [GOC:mah, PMID:15979253, PMID:16306220] +synonym: "mitochondrial migration along actin filament" EXACT [GOC:dph, GOC:tb] +synonym: "mitochondrial migration along microfilament" EXACT [] +synonym: "mitochondrial migration, actin-mediated" EXACT [] +synonym: "mitochondrion migration along microfilament" EXACT [] +synonym: "mitochondrion transport along actin filament" EXACT [] +is_a: GO:0030048 ! actin filament-based movement +is_a: GO:0051654 ! establishment of mitochondrion localization +is_a: GO:0099515 ! actin filament-based transport + +[Term] +id: GO:0034643 +name: establishment of mitochondrion localization, microtubule-mediated +namespace: biological_process +def: "The directed movement of the mitochondrion to a specific location, by a process involving microtubules." [GOC:mah, PMID:12972644, PMID:15979253, PMID:16306220] +synonym: "establishment of mitochondrion localisation, microtubule-mediated" EXACT [GOC:mah] +synonym: "microtubule-mediated mitochondrion localization" EXACT [] +synonym: "mitochondrial localization, microtubule-mediated" EXACT [] +is_a: GO:0007018 ! microtubule-based movement +is_a: GO:0051654 ! establishment of mitochondrion localization + +[Term] +id: GO:0034644 +name: cellular response to UV +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:mah] +synonym: "cellular response to ultraviolet light stimulus" EXACT [] +synonym: "cellular response to ultraviolet radiation stimulus" EXACT [] +synonym: "cellular response to UV light stimulus" EXACT [] +synonym: "cellular response to UV radiation stimulus" EXACT [] +is_a: GO:0009411 ! response to UV +is_a: GO:0071482 ! cellular response to light stimulus + +[Term] +id: GO:0034645 +name: cellular macromolecule biosynthetic process +namespace: biological_process +alt_id: GO:0034961 +def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." [GOC:mah] +synonym: "cellular biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "cellular macromolecule anabolism" EXACT [GOC:mah] +synonym: "cellular macromolecule biosynthesis" EXACT [GOC:mah] +synonym: "cellular macromolecule formation" EXACT [GOC:mah] +synonym: "cellular macromolecule synthesis" EXACT [GOC:mah] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0034646 +name: organelle-enclosing lipid monolayer +namespace: cellular_component +def: "A lipid monolayer that surrounds and encloses an organelle." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0034647 +name: histone demethylase activity (H3-trimethyl-K4 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896] +synonym: "histone demethylase activity (H3-K4-me3 specific)" EXACT [] +xref: EC:1.14.11.67 +is_a: GO:0032453 ! histone demethylase activity (H3-K4 specific) +relationship: part_of GO:0034721 ! histone H3-K4 demethylation, trimethyl-H3-K4-specific + +[Term] +id: GO:0034648 +name: histone demethylase activity (H3-dimethyl-K4 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896] +synonym: "histone demethylase activity (H3-K4-me2 specific)" EXACT [] +is_a: GO:0032453 ! histone demethylase activity (H3-K4 specific) + +[Term] +id: GO:0034649 +name: histone demethylase activity (H3-monomethyl-K4 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:16223729] +synonym: "histone demethylase activity (H3-K4-me1 specific)" EXACT [] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0032453 ! histone demethylase activity (H3-K4 specific) + +[Term] +id: GO:0034650 +name: cortisol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties." [GOC:BHF, GOC:mah, GOC:rl] +synonym: "cortisol metabolism" EXACT [] +is_a: GO:0008211 ! glucocorticoid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process + +[Term] +id: GO:0034651 +name: cortisol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties." [GOC:BHF, GOC:mah, GOC:rl] +synonym: "cortisol anabolism" NARROW [] +synonym: "cortisol biosynthesis" EXACT [] +synonym: "cortisol formation" EXACT [] +synonym: "cortisol synthesis" EXACT [] +is_a: GO:0006704 ! glucocorticoid biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0034650 ! cortisol metabolic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process + +[Term] +id: GO:0034652 +name: extrachromosomal circular DNA localization involved in cell aging +namespace: biological_process +def: "A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging." [GOC:dph, GOC:jp, GOC:tb, PMID:18660802] +comment: Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy. +synonym: "extrachromosomal circular DNA localisation involved in cell aging" EXACT [GOC:mah] +synonym: "extrachromosomal circular DNA localization during cell ageing" EXACT [] +synonym: "extrachromosomal circular DNA localization during cell aging" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001301 ! progressive alteration of chromatin involved in cell aging + +[Term] +id: GO:0034653 +name: retinoic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A." [GOC:BHF, GOC:mah] +synonym: "retinoic acid breakdown" EXACT [] +synonym: "retinoic acid catabolism" EXACT [] +synonym: "retinoic acid degradation" EXACT [] +synonym: "vitamin A1 acid catabolic process" EXACT [] +is_a: GO:0016103 ! diterpenoid catabolic process +is_a: GO:0042363 ! fat-soluble vitamin catabolic process +is_a: GO:0042573 ! retinoic acid metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0034654 +name: nucleobase-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW [] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0034655 +name: nucleobase-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] +synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0034656 +name: nucleobase-containing small molecule catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:mah] +synonym: "nucleobase, nucleoside and nucleotide breakdown" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide catabolism" EXACT [] +synonym: "nucleobase, nucleoside and nucleotide degradation" EXACT [] +is_a: GO:0034655 ! nucleobase-containing compound catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process + +[Term] +id: GO:0034657 +name: GID complex +namespace: cellular_component +def: "A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p." [PMID:12686616, PMID:18508925] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034658 +name: isopropylmalate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of isopropylmalate from one side of a membrane to the other." [GOC:mah] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:0034659 ! isopropylmalate transport + +[Term] +id: GO:0034659 +name: isopropylmalate transport +namespace: biological_process +def: "The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0034660 +name: ncRNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)." [GOC:mah] +synonym: "ncRNA metabolism" EXACT [] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0034661 +name: ncRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs)." [GOC:rb, PMID:18591258] +synonym: "ncRNA breakdown" EXACT [] +synonym: "ncRNA catabolism" EXACT [] +synonym: "ncRNA degradation" EXACT [] +is_a: GO:0006401 ! RNA catabolic process +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0034662 +name: CFTR-NHERF-ezrin complex +namespace: cellular_component +def: "A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity." [PMID:16129695, PMID:16798722, PMID:16926444] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0034663 +name: endoplasmic reticulum chaperone complex +namespace: cellular_component +def: "A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1." [PMID:12475965] +synonym: "endoplasmic reticulum network complex" RELATED [] +synonym: "ER chaperone complex" EXACT [] +synonym: "ER network complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0034664 +name: Ig heavy chain-bound endoplasmic reticulum chaperone complex +namespace: cellular_component +def: "A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1." [PMID:12475965] +synonym: "Ig heavy chain-bound ER chaperone complex" EXACT [] +synonym: "immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex" EXACT [] +is_a: GO:0101031 ! chaperone complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0034665 +name: integrin alpha1-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha1 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha1-beta1 integrin complex" EXACT [] +synonym: "ITGA1-ITGB1 complex" NARROW [] +synonym: "VLA-1 complex" EXACT [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034666 +name: integrin alpha2-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha2 subunit and one beta1 subunit." [PMID:12297042] +synonym: "ITGA2-ITGB1 complex" NARROW [CORUM:2432] +synonym: "VLA-2 complex" EXACT [PMID:3546305] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034667 +name: integrin alpha3-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha3 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha3-beta1 integrin complex" EXACT [] +synonym: "ITGA3-ITGB1 complex" NARROW [CORUM:2406] +synonym: "VLA-3 complex" EXACT [PMID:3546305] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034668 +name: integrin alpha4-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha4 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha4-beta1 integrin complex" EXACT [] +synonym: "ITGA4-ITGB1 complex" NARROW [] +synonym: "VLA-4 complex" EXACT [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034669 +name: integrin alpha4-beta7 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha4 subunit and one beta7 subunit." [PMID:12297042] +synonym: "alpha4-beta7 integrin complex" EXACT [] +synonym: "ITGA4-ITGB7 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034670 +name: chemotaxis to arachidonic acid +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to the presence of arachidonic acid." [GOC:go_curators, PMID:18202452] +is_a: GO:0006935 ! chemotaxis + +[Term] +id: GO:0034671 +name: retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros." [GOC:mh] +synonym: "retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] +synonym: "retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0034672 ! anterior/posterior pattern specification involved in pronephros development +relationship: part_of GO:0034672 ! anterior/posterior pattern specification involved in pronephros development + +[Term] +id: GO:0034672 +name: anterior/posterior pattern specification involved in pronephros development +namespace: biological_process +def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah] +synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0039017 ! pattern specification involved in pronephros development +is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development +intersection_of: GO:0009952 ! anterior/posterior pattern specification +intersection_of: part_of GO:0048793 ! pronephros development + +[Term] +id: GO:0034673 +name: inhibin-betaglycan-ActRII complex +namespace: cellular_component +def: "A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B." [GOC:BHF, PMID:10746731] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0034674 +name: integrin alpha5-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha5 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha5-beta1 integrin complex" EXACT [] +synonym: "ITGA5-ITGB1 complex" NARROW [] +synonym: "VLA-5 complex" EXACT [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034675 +name: integrin alpha6-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha6 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha6-beta1 integrin complex" EXACT [] +synonym: "ITGA6-ITGB1 complex" NARROW [CORUM:2413] +synonym: "VLA-6 complex" EXACT [PMID:2649503] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034676 +name: integrin alpha6-beta4 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha6 subunit and one beta4 subunit." [PMID:12297042] +synonym: "alpha6-beta4 integrin complex" EXACT [] +synonym: "ITGA6-ITGB4 complex" NARROW [CORUM:2323] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034677 +name: integrin alpha7-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha7 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha7-beta1 integrin complex" EXACT [] +synonym: "ITGA7-ITGB1 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034678 +name: integrin alpha8-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha8 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha8-beta1 integrin complex" EXACT [] +synonym: "ITGA8-ITGB1 complex" NARROW [CORUM:2439] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034679 +name: integrin alpha9-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha9 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha9-beta1 integrin complex" EXACT [] +synonym: "ITGA9-ITGB1 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034680 +name: integrin alpha10-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha10 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha10-beta1 integrin complex" EXACT [] +synonym: "ITGA10-ITGB1 complex" NARROW [CORUM:3057] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034681 +name: integrin alpha11-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alpha11 subunit and one beta1 subunit." [PMID:12297042] +synonym: "alpha11-beta1 integrin complex" EXACT [] +synonym: "ITGA11-ITGB1 complex" NARROW [CORUM:3058] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034682 +name: integrin alphav-beta1 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphav subunit and one beta1 subunit." [PMID:12297042] +synonym: "alphav-beta1 integrin complex" EXACT [] +synonym: "ITGAV-ITGB1 complex" NARROW [CORUM:2436] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034683 +name: integrin alphav-beta3 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphav subunit and one beta3 subunit." [PMID:12297042] +synonym: "alphav-beta3 integrin complex" EXACT [] +synonym: "ITGAV-ITGB3 complex" NARROW [CORUM:2816] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034684 +name: integrin alphav-beta5 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphav subunit and one beta5 subunit." [PMID:12297042] +synonym: "alphav-beta5 integrin complex" EXACT [] +synonym: "ITGAV-ITGB5 complex" NARROW [CORUM:2350] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034685 +name: integrin alphav-beta6 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphav subunit and one beta6 subunit." [PMID:12297042] +synonym: "alphav-beta6 integrin complex" EXACT [] +synonym: "ITGAV-ITGB6 complex" NARROW [CORUM:2354] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034686 +name: integrin alphav-beta8 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphav subunit and one beta8 subunit." [PMID:12297042] +synonym: "alphav-beta8 integrin complex" EXACT [] +synonym: "ITGAV-ITGB8 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034687 +name: integrin alphaL-beta2 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaL subunit and one beta2 subunit." [PMID:12297042] +synonym: "alphaL-beta2 integrin complex" EXACT [] +synonym: "Itgal-Itgb2 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034688 +name: integrin alphaM-beta2 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaM subunit and one beta2 subunit." [PMID:12297042] +synonym: "alphaM-beta2 integrin complex" EXACT [] +synonym: "Itgam-Itgb2 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034689 +name: integrin alphaX-beta2 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaX subunit and one beta2 subunit." [PMID:12297042] +synonym: "alphaX-beta2 integrin complex" EXACT [] +synonym: "Itgax-Itgb2 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034690 +name: integrin alphaD-beta2 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaD subunit and one beta2 subunit." [PMID:12297042] +synonym: "alphaD-beta2 integrin complex" EXACT [] +synonym: "Itgad-Itgb2 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034691 +name: integrin alphaE-beta7 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaE subunit and one beta7 subunit." [PMID:12297042] +synonym: "Itgae-Itgb7 complex" NARROW [] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0034692 +name: E.F.G complex +namespace: cellular_component +def: "A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex." [PMID:8641291] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034693 +name: U11/U12 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex formed by the association of the U11 and U12 small nuclear ribonucleoproteins." [GOC:mah, PMID:15146077] +synonym: "18S U11/U12 snRNP" NARROW [] +synonym: "snRNP U11/U12" EXACT [GOC:mah] +is_a: GO:0097525 ! spliceosomal snRNP complex + +[Term] +id: GO:0034694 +name: response to prostaglandin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus." [GOC:BHF, GOC:vk] +synonym: "response to prostaglandin stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +is_a: GO:0070542 ! response to fatty acid + +[Term] +id: GO:0034695 +name: response to prostaglandin E +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus." [GOC:BHF, GOC:vk] +synonym: "response to prostaglandin E stimulus" EXACT [GOC:dos] +is_a: GO:0034694 ! response to prostaglandin +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0034696 +name: response to prostaglandin F +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus." [GOC:BHF, GOC:vk] +synonym: "response to prostaglandin F stimulus" EXACT [GOC:dos] +is_a: GO:0034694 ! response to prostaglandin + +[Term] +id: GO:0034697 +name: response to prostaglandin I +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus." [GOC:BHF, GOC:vk] +synonym: "response to prostaglandin I stimulus" EXACT [GOC:dos] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0034694 ! response to prostaglandin + +[Term] +id: GO:0034698 +name: response to gonadotropin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus." [GOC:BHF, GOC:vk] +synonym: "response to gonadotropin stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone + +[Term] +id: GO:0034699 +name: response to luteinizing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus." [GOC:BHF, GOC:vk] +synonym: "response to luteinizing hormone stimulus" EXACT [GOC:dos] +is_a: GO:0034698 ! response to gonadotropin +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0034700 +name: allulose 6-phosphate 3-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate." [GOC:imk] +xref: MetaCyc:RXN0-304 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0034701 +name: tripeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a tripeptide." [GOC:mah] +xref: EC:3.4.13 +xref: MetaCyc:3.4.11.4-RXN +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0034702 +name: ion channel complex +namespace: cellular_component +def: "A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient." [GOC:mah, ISBN:071673706X] +is_a: GO:1902495 ! transmembrane transporter complex + +[Term] +id: GO:0034703 +name: cation channel complex +namespace: cellular_component +def: "An ion channel complex through which cations pass." [GOC:mah] +is_a: GO:0034702 ! ion channel complex + +[Term] +id: GO:0034704 +name: calcium channel complex +namespace: cellular_component +def: "An ion channel complex through which calcium ions pass." [GOC:mah] +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0034705 +name: potassium channel complex +namespace: cellular_component +def: "An ion channel complex through which potassium ions pass." [GOC:mah] +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0034706 +name: sodium channel complex +namespace: cellular_component +def: "An ion channel complex through which sodium ions pass." [GOC:mah] +is_a: GO:0034703 ! cation channel complex + +[Term] +id: GO:0034707 +name: chloride channel complex +namespace: cellular_component +def: "An ion channel complex through which chloride ions pass." [GOC:mah] +is_a: GO:0034702 ! ion channel complex + +[Term] +id: GO:0034708 +name: methyltransferase complex +namespace: cellular_component +def: "A protein complex that possesses methyltransferase activity." [GOC:mah] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034709 +name: methylosome +namespace: cellular_component +def: "A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains." [PMID:11713266, PMID:11756452] +synonym: "20S methylosome" EXACT [] +synonym: "20S methyltransferase complex" EXACT [] +is_a: GO:0034708 ! methyltransferase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034710 +name: inhibin complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit." [GOC:BHF, GOC:mah] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0034711 +name: inhibin binding +namespace: molecular_function +alt_id: GO:0034712 +alt_id: GO:0048186 +alt_id: GO:0048187 +def: "Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers." [GOC:BHF, GOC:mah] +synonym: "inhibin alpha binding" NARROW [] +synonym: "inhibin beta-A binding" NARROW [] +synonym: "inhibin beta-B binding" NARROW [] +synonym: "inhibin monomer binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0034713 +name: type I transforming growth factor beta receptor binding +namespace: molecular_function +alt_id: GO:0005103 +alt_id: GO:0005116 +alt_id: GO:0005120 +def: "Interacting selectively and non-covalently with a type I transforming growth factor beta receptor." [GOC:BHF, GOC:mah] +synonym: "babo binding" NARROW [] +synonym: "babo ligand" NARROW [] +synonym: "baboon binding" NARROW [] +synonym: "baboon ligand" NARROW [] +synonym: "baboon receptor ligand" NARROW [] +synonym: "sax binding" NARROW [] +synonym: "sax ligand" NARROW [] +synonym: "saxophone binding" NARROW [] +synonym: "saxophone ligand" NARROW [] +synonym: "TGF-beta type I binding" EXACT [] +synonym: "thickveins binding" NARROW [] +synonym: "thickveins ligand" NARROW [] +synonym: "tkv binding" NARROW [] +synonym: "tkv ligand" NARROW [] +synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] +synonym: "transforming growth factor beta receptor type I binding" EXACT [] +synonym: "type I TGF-beta binding" EXACT [] +is_a: GO:0005160 ! transforming growth factor beta receptor binding + +[Term] +id: GO:0034714 +name: type III transforming growth factor beta receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type III transforming growth factor beta receptor." [GOC:BHF, GOC:mah] +synonym: "betaglycan binding" RELATED [] +synonym: "TGF-beta type III binding" EXACT [] +synonym: "transforming growth factor beta ligand binding to type III receptor" RELATED [] +synonym: "transforming growth factor beta receptor type III binding" EXACT [] +synonym: "type IIII TGF-beta binding" EXACT [] +is_a: GO:0005160 ! transforming growth factor beta receptor binding + +[Term] +id: GO:0034715 +name: pICln-Sm protein complex +namespace: cellular_component +def: "A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG." [GOC:mah, PMID:11713266] +synonym: "6S pICln complex" EXACT [] +is_a: GO:0120114 ! Sm-like protein family complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034716 +name: Gemin3-Gemin4-Gemin5 complex +namespace: cellular_component +def: "A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly." [GOC:mah, PMID:17640873] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034717 +name: Gemin6-Gemin7-unrip complex +namespace: cellular_component +def: "A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly." [GOC:mah, PMID:17640873] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034718 +name: SMN-Gemin2 complex +namespace: cellular_component +def: "A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex." [GOC:mah, PMID:17640873] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +is_a: GO:0120114 ! Sm-like protein family complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034719 +name: SMN-Sm protein complex +namespace: cellular_component +def: "A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm." [GOC:vw, PMID:11522829, PMID:17401408] +comment: Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797. +synonym: "SMN-containing protein complex" BROAD [] +is_a: GO:0120114 ! Sm-like protein family complex +relationship: has_part GO:0032797 ! SMN complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034720 +name: histone H3-K4 demethylation +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone." [GOC:mah] +synonym: "H3K4 demethylation (me1 me2 and me3)" RELATED [] +is_a: GO:0070076 ! histone lysine demethylation + +[Term] +id: GO:0034721 +name: histone H3-K4 demethylation, trimethyl-H3-K4-specific +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone." [GOC:mah] +synonym: "H3K4 demethylation (me3)" EXACT [] +synonym: "histone H3-K4 tridemethylation" RELATED [] +is_a: GO:0034720 ! histone H3-K4 demethylation + +[Term] +id: GO:0034722 +name: gamma-glutamyl-peptidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a gamma-linked glutamate bond." [EC:3.4.19.9, MEROPS_fam:C26] +synonym: "gamma-glutamyl hydrolase activity" EXACT [EC:3.4.19.9] +xref: EC:3.4.19.9 +xref: MetaCyc:3.4.19.9-RXN +is_a: GO:0008242 ! omega peptidase activity + +[Term] +id: GO:0034723 +name: DNA replication-dependent nucleosome organization +namespace: biological_process +def: "The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation." [GOC:mah, PMID:17510629] +synonym: "DNA replication-dependent nucleosome organisation" EXACT [] +is_a: GO:0006333 ! chromatin assembly or disassembly +is_a: GO:0034728 ! nucleosome organization + +[Term] +id: GO:0034724 +name: DNA replication-independent nucleosome organization +namespace: biological_process +def: "The formation or destruction of chromatin structures, occurring outside the context of DNA replication." [GOC:mah, PMID:17510629] +synonym: "DNA replication-independent nucleosome organisation" EXACT [] +is_a: GO:0006333 ! chromatin assembly or disassembly +is_a: GO:0034728 ! nucleosome organization + +[Term] +id: GO:0034725 +name: DNA replication-dependent nucleosome disassembly +namespace: biological_process +def: "The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation." [GOC:mah, PMID:17510629] +is_a: GO:0006337 ! nucleosome disassembly +is_a: GO:0034723 ! DNA replication-dependent nucleosome organization + +[Term] +id: GO:0034726 +name: DNA replication-independent nucleosome disassembly +namespace: biological_process +def: "The controlled breakdown of nucleosomes outside the context of DNA replication." [GOC:mah, PMID:17510629] +is_a: GO:0006337 ! nucleosome disassembly +is_a: GO:0034724 ! DNA replication-independent nucleosome organization + +[Term] +id: GO:0034727 +name: piecemeal microautophagy of the nucleus +namespace: biological_process +def: "Degradation of a cell nucleus by lysosomal microautophagy." [GOC:autophagy, GOC:jp, PMID:18701704] +synonym: "PMN" EXACT [] +is_a: GO:0016237 ! lysosomal microautophagy +is_a: GO:0044804 ! autophagy of nucleus +relationship: has_part GO:1905690 ! nucleus disassembly + +[Term] +id: GO:0034728 +name: nucleosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes." [GOC:mah] +synonym: "nucleosome organisation" EXACT [] +is_a: GO:0006325 ! chromatin organization +is_a: GO:0071824 ! protein-DNA complex subunit organization + +[Term] +id: GO:0034729 +name: histone H3-K79 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone." [GOC:se] +synonym: "histone H3 K79 methylation" EXACT [] +synonym: "histone H3K79me" EXACT [] +synonym: "histone lysine H3 K79 methylation" EXACT [] +is_a: GO:0034968 ! histone lysine methylation + +[Term] +id: GO:0034730 +name: SmD-containing SMN-Sm protein complex +namespace: cellular_component +def: "An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex." [PMID:12975319, PMID:17401408] +synonym: "SMN-containing protein complex" BROAD [] +is_a: GO:0034719 ! SMN-Sm protein complex + +[Term] +id: GO:0034731 +name: Lsm-containing SMN-Sm protein complex +namespace: cellular_component +def: "An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA." [PMID:12975319, PMID:17401408] +synonym: "SMN-containing protein complex" BROAD [] +is_a: GO:0034719 ! SMN-Sm protein complex + +[Term] +id: GO:0034732 +name: transcription factor TFIIIB-alpha complex +namespace: cellular_component +def: "A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters." [PMID:11433012] +is_a: GO:0000126 ! transcription factor TFIIIB complex + +[Term] +id: GO:0034733 +name: transcription factor TFIIIB-beta complex +namespace: cellular_component +def: "A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters." [PMID:11433012] +comment: Note that the subunits of TFIIIB-beta are conserved between human and yeast; however, in yeast a single TFIIIB complex regulates transcription of tRNA, 5S rRNA and U6 snRNA genes, whereas two different TBP-dependent TFIIIB activities exist in humans. +is_a: GO:0000126 ! transcription factor TFIIIB complex + +[Term] +id: GO:0034734 +name: transcription factor TFIIIC1 complex +namespace: cellular_component +def: "A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity." [GOC:mah, PMID:11433012, PMID:15096501] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex +relationship: part_of GO:0000127 ! transcription factor TFIIIC complex + +[Term] +id: GO:0034735 +name: transcription factor TFIIIC2 complex +namespace: cellular_component +def: "A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter." [GOC:mah, PMID:11433012] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex +relationship: part_of GO:0000127 ! transcription factor TFIIIC complex + +[Term] +id: GO:0034736 +name: cholesterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA." [EC:2.3.1.26, RHEA:17729] +synonym: "ACAT activity" BROAD [EC:2.3.1.26] +synonym: "acyl coenzyme A-cholesterol-O-acyltransferase activity" EXACT [EC:2.3.1.26] +synonym: "acyl-CoA:cholesterol acyltransferase activity" EXACT [EC:2.3.1.26] +synonym: "acyl-CoA:cholesterol O-acyltransferase activity" EXACT [EC:2.3.1.26] +synonym: "acylcoenzyme A:cholesterol O-acyltransferase activity" EXACT [] +synonym: "cholesterol acyltransferase activity" BROAD [EC:2.3.1.26] +synonym: "cholesterol ester synthetase activity" EXACT [EC:2.3.1.26] +synonym: "cholesteryl ester synthetase activity" EXACT [EC:2.3.1.26] +xref: EC:2.3.1.26 +xref: KEGG_REACTION:R01461 +xref: MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-8876696 "SOAT1,2 transfer acyl group to CHOL forming CHEST" +xref: RHEA:17729 +is_a: GO:0004772 ! sterol O-acyltransferase activity +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4930 + +[Term] +id: GO:0034737 +name: ergosterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester." [GOC:mah] +is_a: GO:0004772 ! sterol O-acyltransferase activity + +[Term] +id: GO:0034738 +name: lanosterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester." [GOC:mah] +is_a: GO:0004772 ! sterol O-acyltransferase activity + +[Term] +id: GO:0034739 +name: histone deacetylase activity (H4-K16 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein." [EC:3.5.1.17, GOC:vw, RHEA:24548] +is_a: GO:0004407 ! histone deacetylase activity +relationship: part_of GO:0070933 ! histone H4 deacetylation + +[Term] +id: GO:0034740 +name: TFIIIC-TOP1-SUB1 complex +namespace: cellular_component +def: "A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III." [PMID:9660958] +synonym: "TFIIIC-Topoisomerase 1-PC4 complex" EXACT [] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex + +[Term] +id: GO:0034741 +name: APC-tubulin-IQGAP1 complex +namespace: cellular_component +def: "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization." [PMID:17126424] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +synonym: "60S APC complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034743 +name: APC-IQGAP complex +namespace: cellular_component +def: "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0034744 +name: APC-IQGAP1-Cdc42 complex +namespace: cellular_component +def: "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0034745 +name: APC-IQGAP1-Rac1 complex +namespace: cellular_component +def: "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration." [PMID:15572129] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0034746 +name: APC-IQGAP1-CLIP-170 complex +namespace: cellular_component +def: "A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration." [PMID:15572129] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0034748 +name: Par3-APC-KIF3A complex +namespace: cellular_component +def: "A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity." [PMID:15556865] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034749 +name: Scrib-APC complex +namespace: cellular_component +def: "A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation." [PMID:16611247] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +synonym: "hScrib-APC complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034750 +name: Scrib-APC-beta-catenin complex +namespace: cellular_component +def: "A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation." [PMID:16611247] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +synonym: "hScrib-APC-beta-catenin complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034751 +name: aryl hydrocarbon receptor complex +namespace: cellular_component +def: "A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR." [GOC:mah, PMID:7598497] +synonym: "AhR complex" EXACT [] +synonym: "AHRC" EXACT [] +is_a: GO:0043235 ! receptor complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034752 +name: cytosolic aryl hydrocarbon receptor complex +namespace: cellular_component +def: "An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP." [PMID:7598497, PMID:8937476, PMID:9447995] +synonym: "9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex" RELATED [] +synonym: "cytosolic AhR complex" EXACT [] +synonym: "cytosolic AHRC" EXACT [] +is_a: GO:0034751 ! aryl hydrocarbon receptor complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0034753 +name: nuclear aryl hydrocarbon receptor complex +namespace: cellular_component +def: "An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT)." [PMID:7598497] +synonym: "6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex" RELATED [] +synonym: "nuclear AhR complex" EXACT [] +synonym: "nuclear AHRC" EXACT [] +is_a: GO:0034751 ! aryl hydrocarbon receptor complex +intersection_of: GO:0034751 ! aryl hydrocarbon receptor complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034754 +name: cellular hormone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells." [GOC:mah] +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0034755 +name: iron ion transmembrane transport +namespace: biological_process +alt_id: GO:0000040 +alt_id: GO:0006827 +alt_id: GO:0061839 +alt_id: GO:1903874 +def: "A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah, PMID:11390404] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "ferrous ion transmembrane transport" NARROW [] +synonym: "ferrous iron transmembrane transport" NARROW [] +synonym: "high affinity ferrous ion transmembrane transport" NARROW [] +synonym: "high affinity iron ion transport" NARROW [] +synonym: "high-affinity ferrous ion transmembrane transport" NARROW [] +synonym: "high-affinity iron ion transmembrane transport" NARROW [] +synonym: "high-affinity iron ion transport" NARROW [] +synonym: "iron ion membrane transport" EXACT [] +synonym: "iron(2+) transmembrane transport" NARROW [] +synonym: "low affinity iron ion transport" NARROW [] +synonym: "low-affinity iron ion transmembrane transport" NARROW [] +synonym: "low-affinity iron ion transport" NARROW [] +synonym: "transmembrane iron transport" EXACT [] +is_a: GO:0006826 ! iron ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: vw +creation_date: 2015-02-06T11:29:22Z + +[Term] +id: GO:0034756 +name: regulation of iron ion transport +namespace: biological_process +alt_id: GO:1900390 +def: "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "regulation of Fe transport" EXACT [] +synonym: "regulation of iron import" NARROW [GOC:TermGenie] +synonym: "regulation of iron ion import" NARROW [] +synonym: "regulation of iron transport" EXACT [] +is_a: GO:0010959 ! regulation of metal ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006826 ! iron ion transport +relationship: regulates GO:0006826 ! iron ion transport +created_by: mah +creation_date: 2012-04-18T04:00:14Z + +[Term] +id: GO:0034757 +name: negative regulation of iron ion transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of iron ion transport" EXACT [] +synonym: "down-regulation of iron ion transport" EXACT [] +synonym: "downregulation of iron ion transport" EXACT [] +synonym: "inhibition of iron ion transport" NARROW [] +synonym: "negative regulation of iron transport" EXACT [] +is_a: GO:0034756 ! regulation of iron ion transport +is_a: GO:0043271 ! negative regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006826 ! iron ion transport +relationship: negatively_regulates GO:0006826 ! iron ion transport + +[Term] +id: GO:0034758 +name: positive regulation of iron ion transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of iron ion transport" NARROW [] +synonym: "positive regulation of iron transport" EXACT [] +synonym: "stimulation of iron ion transport" NARROW [] +synonym: "up regulation of iron ion transport" EXACT [] +synonym: "up-regulation of iron ion transport" EXACT [] +synonym: "upregulation of iron ion transport" EXACT [] +is_a: GO:0034756 ! regulation of iron ion transport +is_a: GO:0043270 ! positive regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006826 ! iron ion transport +relationship: positively_regulates GO:0006826 ! iron ion transport + +[Term] +id: GO:0034759 +name: regulation of iron ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "regulation of iron ion membrane transport" EXACT [] +synonym: "regulation of transmembrane Fe transport" EXACT [] +synonym: "regulation of transmembrane iron ion transport" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of transmembrane iron transport" EXACT [] +is_a: GO:0034756 ! regulation of iron ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034755 ! iron ion transmembrane transport +relationship: regulates GO:0034755 ! iron ion transmembrane transport + +[Term] +id: GO:0034760 +name: negative regulation of iron ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "down regulation of transmembrane iron ion transport" EXACT [] +synonym: "down-regulation of transmembrane iron ion transport" EXACT [] +synonym: "downregulation of transmembrane iron ion transport" EXACT [] +synonym: "inhibition of transmembrane iron ion transport" NARROW [] +synonym: "negative regulation of iron ion membrane transport" EXACT [] +synonym: "negative regulation of transmembrane iron ion transport" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of transmembrane iron transport" EXACT [] +is_a: GO:0034757 ! negative regulation of iron ion transport +is_a: GO:0034759 ! regulation of iron ion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034755 ! iron ion transmembrane transport +relationship: negatively_regulates GO:0034755 ! iron ion transmembrane transport + +[Term] +id: GO:0034761 +name: positive regulation of iron ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "activation of transmembrane iron ion transport" NARROW [] +synonym: "positive regulation of iron ion membrane transport" EXACT [] +synonym: "positive regulation of transmembrane iron ion transport" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of transmembrane iron transport" EXACT [] +synonym: "stimulation of transmembrane iron ion transport" NARROW [] +synonym: "up regulation of transmembrane iron ion transport" EXACT [] +synonym: "up-regulation of transmembrane iron ion transport" EXACT [] +synonym: "upregulation of transmembrane iron ion transport" EXACT [] +is_a: GO:0034758 ! positive regulation of iron ion transport +is_a: GO:0034759 ! regulation of iron ion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034755 ! iron ion transmembrane transport +relationship: positively_regulates GO:0034755 ! iron ion transmembrane transport + +[Term] +id: GO:0034762 +name: regulation of transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] +synonym: "regulation of membrane transport" EXACT [] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055085 ! transmembrane transport +relationship: regulates GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034763 +name: negative regulation of transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] +synonym: "down regulation of transmembrane transport" EXACT [] +synonym: "down-regulation of transmembrane transport" EXACT [] +synonym: "downregulation of transmembrane transport" EXACT [] +synonym: "inhibition of transmembrane transport" NARROW [] +synonym: "negative regulation of membrane transport" EXACT [] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055085 ! transmembrane transport +relationship: negatively_regulates GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034764 +name: positive regulation of transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] +synonym: "activation of transmembrane transport" NARROW [] +synonym: "positive regulation of membrane transport" EXACT [] +synonym: "stimulation of transmembrane transport" NARROW [] +synonym: "up regulation of transmembrane transport" EXACT [] +synonym: "up-regulation of transmembrane transport" EXACT [] +synonym: "upregulation of transmembrane transport" EXACT [] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055085 ! transmembrane transport +relationship: positively_regulates GO:0055085 ! transmembrane transport + +[Term] +id: GO:0034765 +name: regulation of ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] +synonym: "regulation of ion membrane transport" EXACT [] +synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:0043269 ! regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034220 ! ion transmembrane transport +relationship: regulates GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0034766 +name: negative regulation of ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] +synonym: "down regulation of transmembrane ion transport" EXACT [] +synonym: "down-regulation of transmembrane ion transport" EXACT [] +synonym: "downregulation of transmembrane ion transport" EXACT [] +synonym: "inhibition of transmembrane ion transport" NARROW [] +synonym: "negative regulation of ion membrane transport" EXACT [] +synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:0034765 ! regulation of ion transmembrane transport +is_a: GO:0043271 ! negative regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034220 ! ion transmembrane transport +relationship: negatively_regulates GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0034767 +name: positive regulation of ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] +synonym: "activation of transmembrane ion transport" NARROW [] +synonym: "positive regulation of ion membrane transport" EXACT [] +synonym: "positive regulation of transmembrane ion transport" EXACT [] +synonym: "stimulation of transmembrane ion transport" NARROW [] +synonym: "up regulation of transmembrane ion transport" EXACT [] +synonym: "up-regulation of transmembrane ion transport" EXACT [] +synonym: "upregulation of transmembrane ion transport" EXACT [] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:0034765 ! regulation of ion transmembrane transport +is_a: GO:0043270 ! positive regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034220 ! ion transmembrane transport +relationship: positively_regulates GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0034768 +name: (E)-beta-ocimene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate." [EC:4.2.3.106, PMID:12624761] +xref: EC:4.2.3.106 +xref: MetaCyc:RXN-5109 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0034769 +name: basement membrane disassembly +namespace: biological_process +alt_id: GO:0060881 +def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221] +comment: Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer. +synonym: "basal lamina disassembly" RELATED [] +is_a: GO:0022617 ! extracellular matrix disassembly +is_a: GO:0071711 ! basement membrane organization +created_by: dph +creation_date: 2009-08-13T11:27:24Z + +[Term] +id: GO:0034770 +name: histone H4-K20 methylation +namespace: biological_process +def: "The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone." [GOC:mah] +synonym: "histone H4 K20 methylation" EXACT [] +synonym: "histone H4K20me" EXACT [] +synonym: "histone lysine H4 K20 methylation" EXACT [] +is_a: GO:0034968 ! histone lysine methylation + +[Term] +id: GO:0034771 +name: histone H4-K20 monomethylation +namespace: biological_process +def: "The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone." [GOC:mah] +synonym: "histone H4 K20 monomethylation" EXACT [] +synonym: "histone lysine H4 K20 monomethylation" EXACT [] +is_a: GO:0018026 ! peptidyl-lysine monomethylation +is_a: GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0034772 +name: histone H4-K20 dimethylation +namespace: biological_process +def: "The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone." [GOC:mah] +synonym: "histone H4 K20 dimethylation" EXACT [] +synonym: "histone lysine H4 K20 dimethylation" EXACT [] +is_a: GO:0018027 ! peptidyl-lysine dimethylation +is_a: GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0034773 +name: histone H4-K20 trimethylation +namespace: biological_process +def: "The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone." [GOC:mah] +synonym: "histone H4 K20 trimethylation" EXACT [] +synonym: "histone lysine H4 K20 trimethylation" EXACT [] +is_a: GO:0018023 ! peptidyl-lysine trimethylation +is_a: GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0034774 +name: secretory granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a secretory granule." [GOC:rph] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0030141 ! secretory granule +relationship: part_of GO:0030141 ! secretory granule + +[Term] +id: GO:0034775 +name: glutathione transmembrane transport +namespace: biological_process +def: "A process in which glutathione is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "glutathione membrane transport" EXACT [] +synonym: "transmembrane glutathione transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0034635 ! glutathione transport +is_a: GO:0035443 ! tripeptide transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport + +[Term] +id: GO:0034776 +name: response to histamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." [GOC:BHF, GOC:mah, GOC:vk] +synonym: "response to histamine stimulus" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound + +[Term] +id: GO:0034777 +name: recycling endosome lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of a recycling endosome." [GOC:rph] +is_a: GO:0031904 ! endosome lumen +relationship: part_of GO:0055037 ! recycling endosome + +[Term] +id: GO:0034778 +name: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1003] +xref: UM-BBD_reactionID:r1003 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034779 +name: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA." [UM-BBD_reactionID:r1004] +xref: UM-BBD_reactionID:r1004 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034780 +name: glyphosate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-." [UM-BBD_reactionID:r0073] +xref: UM-BBD_reactionID:r0073 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0034781 +name: N-cyclohexylformamide amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate." [UM-BBD_reactionID:r1030] +xref: UM-BBD_reactionID:r1030 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034782 +name: dimethylmalonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2." [UM-BBD_reactionID:r1031] +xref: UM-BBD_reactionID:r1031 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034783 +name: pivalate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP." [UM-BBD_reactionID:r1032] +xref: UM-BBD_reactionID:r1032 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034784 +name: pivalyl-CoA mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA." [UM-BBD_reactionID:r1033] +xref: EC:5.4.99 +xref: UM-BBD_reactionID:r1033 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0034785 +name: salicylate 5-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+." [UM-BBD_reactionID:r1034] +xref: EC:1.14.13 +xref: MetaCyc:RXN-10446 +xref: UM-BBD_reactionID:r1034 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034786 +name: 9-fluorenone-3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone." [UM-BBD_reactionID:r1039] +xref: UM-BBD_reactionID:r1039 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034787 +name: 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-." [UM-BBD_reactionID:r1040] +xref: UM-BBD_reactionID:r1040 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034788 +name: 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+." [UM-BBD_reactionID:r1041] +xref: UM-BBD_reactionID:r1041 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0034789 +name: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+." [UM-BBD_reactionID:r1042] +xref: UM-BBD_reactionID:r1042 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034790 +name: 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-." [UM-BBD_reactionID:r1043] +xref: UM-BBD_reactionID:r1043 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034791 +name: isobutylamine N-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O." [UM-BBD_reactionID:r1053] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r1053 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034792 +name: hypophosphite dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2." [UM-BBD_reactionID:r1058] +xref: UM-BBD_reactionID:r1058 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0034793 +name: cyclopropanecarboxylate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-." [UM-BBD_reactionID:r1056] +xref: UM-BBD_reactionID:r1056 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034794 +name: cyclopropanecarboxyl-CoA decyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA." [UM-BBD_reactionID:r1057] +xref: EC:5.5.1 +xref: UM-BBD_reactionID:r1057 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0034795 +name: cyclohexane monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O." [UM-BBD_reactionID:r1059] +synonym: "butane monooxygenase activity" RELATED [] +synonym: "cyclohexane hydroxylase activity" EXACT [MetaCyc:RXN-8697] +xref: EC:1.14.15 +xref: KEGG_REACTION:R06945 +xref: MetaCyc:RXN-8697 +xref: UM-BBD_reactionID:r1059 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034796 +name: adipate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-." [UM-BBD_reactionID:r1060] +xref: UM-BBD_reactionID:r1060 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034797 +name: fosfomycin 2-glutathione ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid." [UM-BBD_reactionID:r1073] +xref: UM-BBD_reactionID:r1073 +is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds + +[Term] +id: GO:0034798 +name: fosfomycin 2-L-cysteine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid." [UM-BBD_reactionID:r1074] +xref: UM-BBD_reactionID:r1074 +is_a: GO:0016877 ! ligase activity, forming carbon-sulfur bonds + +[Term] +id: GO:0034799 +name: dihydride TNP tautomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form)." [UM-BBD_reactionID:r1070] +xref: UM-BBD_reactionID:r1070 +is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups + +[Term] +id: GO:0034800 +name: trinitrophenol dihydride denitratase activity +namespace: molecular_function +def: "Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP." [UM-BBD_reactionID:r1067] +synonym: "2,4,6-trinitrophenol dihydride denitratase activity" EXACT [] +synonym: "TNP dihydride denitratase activity" EXACT [] +xref: EC:1.7.99 +xref: UM-BBD_reactionID:r1067 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0034801 +name: 2,4-dinitrocyclohexanone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate." [UM-BBD_reactionID:r1069] +xref: UM-BBD_reactionID:r1069 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034802 +name: branched-chain dodecylbenzene sulfonate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite." [UM-BBD_reactionID:r1079] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r1079 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034803 +name: 3-hydroxy-2-naphthoate 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate." [UM-BBD_reactionID:r1104] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1104 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034804 +name: benzo(a)pyrene 11,12-epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide." [UM-BBD_reactionID:r1119] +xref: EC:1.14.99 +xref: UM-BBD_reactionID:r1119 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034805 +name: benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-." [UM-BBD_reactionID:r1121] +xref: UM-BBD_reactionID:r1121 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034806 +name: benzo(a)pyrene 11,12-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol." [UM-BBD_reactionID:r1124] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1124 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034807 +name: 4,5-dihydroxybenzo(a)pyrene methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene." [UM-BBD_reactionID:r1131] +xref: UM-BBD_reactionID:r1131 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0034808 +name: benzo(a)pyrene 4,5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol." [UM-BBD_reactionID:r1126] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1126 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034809 +name: benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2." [UM-BBD_reactionID:r1127] +xref: UM-BBD_reactionID:r1127 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034810 +name: 4,5-dihydroxybenzo(a)pyrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate." [UM-BBD_reactionID:r1128] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1128 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034811 +name: benzo(a)pyrene 9,10-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol." [UM-BBD_reactionID:r1132] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1132 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034812 +name: 9,10-dihydroxybenzo(a)pyrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate." [UM-BBD_reactionID:r1134] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1134 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034813 +name: benzo(a)pyrene 7,8-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol." [UM-BBD_reactionID:1137] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1137 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034814 +name: 7,8-dihydroxy benzo(a)pyrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate." [UM-BBD_reactionID:r1138] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1138 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034815 +name: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+." [UM-BBD_reactionID:r1135] +xref: EC:4.1.3 +xref: UM-BBD_reactionID:r1135 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0034816 +name: anthracene 9,10-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol." [UM-BBD_reactionID:r1141] +xref: UM-BBD_reactionID:r1141 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034817 +name: cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-." [UM-BBD_reactionID:r1144] +xref: UM-BBD_reactionID:r1144 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034818 +name: ADD 9alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin." [UM-BBD_reactionID:r1149] +xref: EC:1.14.15 +xref: UM-BBD_reactionID:r1149 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034819 +name: 3-HSA hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O." [UM-BBD_reactionID:r1150] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r1150 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034820 +name: 4,9-DSHA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+." [UM-BBD_reactionID:r1152] +xref: UM-BBD_reactionID:r1152 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034821 +name: citronellol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+." [UM-BBD_reactionID:r1155] +xref: UM-BBD_reactionID:r1155 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034822 +name: citronellal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+." [UM-BBD_reactionID:r1156] +xref: UM-BBD_reactionID:r1156 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034823 +name: citronellyl-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi." [UM-BBD_reactionID:r1157] +xref: KEGG_REACTION:R08088 +xref: UM-BBD_reactionID:r1157 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034824 +name: citronellyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+." [UM-BBD_reactionID:r1159] +xref: UM-BBD_reactionID:r1159 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034825 +name: tetralin ring-hydroxylating dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+." [UM-BBD_reactionID:r1169] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r1169 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034826 +name: 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+." [UM-BBD_reactionID:r1170] +xref: UM-BBD_reactionID:r1170 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034827 +name: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+." [UM-BBD_reactionID:r1171] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1171 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034828 +name: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+." [UM-BBD_reactionID:r1172] +xref: UM-BBD_reactionID:r1172 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034829 +name: 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate." [UM-BBD_reactionID:r1172] +xref: UM-BBD_reactionID:r1172 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034830 +name: (2Z)-2,4-dihydroxydec-2-enedioate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate." [UM-BBD_reactionID:r1174] +xref: EC:4.1.3 +xref: UM-BBD_reactionID:r1174 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0034831 +name: (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-." [UM-BBD_reactionID:r1176] +xref: UM-BBD_reactionID:r1176 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034832 +name: geranial dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+." [UM-BBD_reactionID:r1164] +xref: UM-BBD_reactionID:r1164 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034833 +name: geranylate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-." [UM-BBD_reactionID:r1165] +xref: UM-BBD_reactionID:r1165 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0034834 +name: 2-mercaptobenzothiazole dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol." [UM-BBD_reactionID:r1177] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1177 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034835 +name: 2-mercaptobenzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole." [UM-BBD_reactionID:r1178] +xref: EC:1.13.12 +xref: UM-BBD_reactionID:r1178 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0034836 +name: 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole." [UM-BBD_reactionID:r1181] +xref: EC:1.13.12 +xref: UM-BBD_reactionID:r1181 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0034837 +name: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-." [UM-BBD_reactionID:r1179] +xref: UM-BBD_reactionID:r1179 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034838 +name: menthone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+." [UM-BBD_reactionID:r1183] +xref: UM-BBD_reactionID:r1183 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034839 +name: menth-2-enone hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone." [UM-BBD_reactionID:r1184] +xref: UM-BBD_reactionID:r1184 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034840 +name: 3-hydroxymenthone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+." [UM-BBD_reactionID:r1185] +xref: UM-BBD_reactionID:r1185 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034841 +name: mentha-1,3-dione-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA." [UM-BBD_reactionID:r1186] +xref: UM-BBD_reactionID:r1186 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034842 +name: thiophene-2-carboxylate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi." [UM-BBD_reactionID:r1234] +xref: UM-BBD_reactionID:r1234 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034843 +name: 2-oxoglutaryl-CoA thioesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH." [UM-BBD_reactionID:r1238] +xref: UM-BBD_reactionID:r1238 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0034844 +name: naphthyl-2-methyl-succinate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate." [UM-BBD_reactionID:r1256] +xref: UM-BBD_reactionID:r1256 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0034845 +name: naphthyl-2-methyl-succinyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1258] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r1258 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034846 +name: naphthyl-2-methylene-succinyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA." [UM-BBD_reactionID:r1259] +xref: UM-BBD_reactionID:r1259 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034847 +name: naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1260] +xref: UM-BBD_reactionID:r1260 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034848 +name: naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA." [UM-BBD_reactionID:r1261] +xref: UM-BBD_reactionID:r1261 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034849 +name: 2-naphthoate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH." [UM-BBD_reactionID:r1262] +xref: UM-BBD_reactionID:r1262 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0034850 +name: isooctane monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol." [UM-BBD_reactionID:r1269] +xref: EC:1.13.12 +xref: UM-BBD_reactionID:r1269 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0034851 +name: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA." [UM-BBD_reactionID:r1274] +xref: UM-BBD_reactionID:r1274 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034852 +name: 4,4-dimethyl-3-oxopentanal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-." [UM-BBD_reactionID:r1309] +xref: UM-BBD_reactionID:r1309 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0034853 +name: 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2." [UM-BBD_reactionID:r1278] +xref: UM-BBD_reactionID:r1278 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034854 +name: 4,4-dimethyl-3-oxopentanoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2." [UM-BBD_reactionID:r1280] +xref: UM-BBD_reactionID:r1280 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034855 +name: 4-AD 9alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O." [UM-BBD_reactionID:r1153] +xref: EC:1.14.15 +xref: UM-BBD_reactionID:r1153 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034856 +name: 2-hydroxyhexa-2,4-dienoate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate." [UM-BBD_reactionID:r1281] +xref: EC:4.2.1.132 +xref: RHEA:32535 +xref: UM-BBD_reactionID:r1281 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034857 +name: 2-(methylthio)benzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole." [UM-BBD_reactionID:r1287] +xref: UM-BBD_reactionID:r1287 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034858 +name: 2-hydroxybenzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole." [UM-BBD_reactionID:r1291] +xref: UM-BBD_reactionID:r1291 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034859 +name: benzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole." [UM-BBD_reactionID:r1292] +xref: UM-BBD_reactionID:r1292 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034860 +name: 2-mercaptobenzothiazole desulfurase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor." [UM-BBD_reactionID:r1288] +xref: EC:4.4.1 +xref: UM-BBD_reactionID:r1288 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0034861 +name: benzothiazole-2-sulfonate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-." [UM-BBD_reactionID:r1290] +xref: EC:3.13.1 +xref: UM-BBD_reactionID:r1290 +is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds + +[Term] +id: GO:0034862 +name: 2,6-dihydroxybenzothiazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole." [UM-BBD_reactionID:r1294] +xref: UM-BBD_reactionID:r1294 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034863 +name: 2,4,4-trimethyl-1-pentanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-." [UM-BBD_reactionID:r1270] +xref: UM-BBD_reactionID:r1270 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034864 +name: 2,4,4-trimethylpentanal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-." [UM-BBD_reactionID:r1275] +xref: UM-BBD_reactionID:r1275 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0034865 +name: 2,4,4-trimethylpentanoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-." [UM-BBD_reactionID:r1271] +xref: UM-BBD_reactionID:r1271 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034866 +name: 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1276] +xref: UM-BBD_reactionID:r1276 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034867 +name: 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA." [UM-BBD_reactionID:r1277] +xref: UM-BBD_reactionID:r1277 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034868 +name: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r1273] +xref: UM-BBD_reactionID:r1273 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034869 +name: 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH." [UM-BBD_reactionID:r1307] +xref: UM-BBD_reactionID:r1307 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0034870 +name: pinacolone 5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one." [UM-BBD_reactionID:r12979] +xref: UM-BBD_reactionID:r12979 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034871 +name: 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-." [UM-BBD_reactionID:r1308] +xref: UM-BBD_reactionID:r1308 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034872 +name: trans-geranyl-CoA isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA." [UM-BBD_reactionID:r1310] +xref: EC:5.2.1 +xref: UM-BBD_reactionID:r1310 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0034873 +name: thioacetamide S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O." [UM-BBD_reactionID:r1312] +xref: UM-BBD_reactionID:r1312 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034874 +name: thioacetamide S-oxide S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O." [UM-BBD_reactionID:r1313] +xref: UM-BBD_reactionID:r1313 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034875 +name: caffeine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O." [UM-BBD_reactionID:r1321] +xref: EC:1.17.5 +xref: UM-BBD_reactionID:r1321 +is_a: GO:0033695 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor + +[Term] +id: GO:0034876 +name: isonicotinic acid hydrazide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine." [UM-BBD_reactionID:r1336] +xref: UM-BBD_reactionID:r1336 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034877 +name: isonicotinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor." [UM-BBD_reactionID:r1337] +xref: UM-BBD_reactionID:r1337 +is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor + +[Term] +id: GO:0034878 +name: 2-hydroxyisonicotinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor." [UM-BBD_reactionID:r1338] +xref: UM-BBD_reactionID:r1338 +is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor + +[Term] +id: GO:0034879 +name: 2,3,6-trihydroxyisonicotinate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2." [UM-BBD_reactionID:r1340] +xref: UM-BBD_reactionID:r1340 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034880 +name: citrazinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-." [UM-BBD_reactionID:r1339] +xref: UM-BBD_reactionID:r1339 +is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor + +[Term] +id: GO:0034881 +name: citrazinate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: citrazinate + H2O = cis-aconitamide." [UM-BBD_reactionID:r1343] +xref: UM-BBD_reactionID:r1343 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0034882 +name: cis-aconitamide amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3." [UM-BBD_reactionID:r1344] +xref: UM-BBD_reactionID:r1344 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034883 +name: obsolete isonicotinate reductase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate." [UM-BBD_reactionID:r1347] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "isonicotinate reductase activity" EXACT [] +is_obsolete: true +consider: GO:0016627 + +[Term] +id: GO:0034884 +name: obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-." [UM-BBD_reactionID:r1349] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "gamma-N-formylaminovinylacetaldehyde dehydrogenase activity" EXACT [] +is_obsolete: true +consider: GO:0016903 + +[Term] +id: GO:0034885 +name: gamma-N-formylaminovinylacetate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH." [UM-BBD_reactionID:r1350] +xref: UM-BBD_reactionID:r1350 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0034886 +name: gamma-aminovinylacetate deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3." [UM-BBD_reactionID:r1351] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r1351 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034887 +name: obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2." [UM-BBD_reactionID:r1348] +comment: This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity. +synonym: "1,4-dihydroisonicotinate 2,3-dioxygenase activity" EXACT [] +is_obsolete: true +consider: GO:0016702 + +[Term] +id: GO:0034888 +name: endosulfan monooxygenase I activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O." [UM-BBD_reactionID:r1382] +xref: UM-BBD_reactionID:r1382 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034889 +name: endosulfan hemisulfate sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate." [UM-BBD_reactionID:r1384] +xref: UM-BBD_reactionID:r1384 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0034890 +name: endosulfan diol hydrolyase (cyclizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O." [UM-BBD_reactionID:r1386] +xref: UM-BBD_reactionID:r1386 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034891 +name: endosulfan diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-." [UM-BBD_reactionID:r1388] +xref: UM-BBD_reactionID:r1388 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034892 +name: endosulfan lactone lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+." [UM-BBD_reactionID:r1389] +xref: UM-BBD_reactionID:r1389 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0034893 +name: N-nitrodimethylamine hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O." [UM-BBD_reactionID:r1395] +xref: UM-BBD_reactionID:r1395 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034894 +name: 4-hydroxypyridine-3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+." [UM-BBD_reactionID:r1397] +xref: EC:1.14.13 +xref: UM-BBD_reactionID:r1397 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034895 +name: pyridine-3,4-diol dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate." [UM-BBD_reactionID:r1398] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1398 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034896 +name: 3-formiminopyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3." [UM-BBD_reactionID:r1400] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r1400 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034897 +name: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol." [UM-BBD_reactionID:r1358] +xref: UM-BBD_reactionID:r1358 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034898 +name: hexadecyltrimethylammonium chloride monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O." [UM-BBD_reactionID:r1373] +xref: EC:1.13.12 +xref: UM-BBD_reactionID:r1373 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0034899 +name: trimethylamine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O." [EC:1.14.13.148, UM-BBD_reactionID:r1407] +xref: EC:1.14.13.148 +xref: KEGG_REACTION:R05623 +xref: RHEA:31979 +xref: UM-BBD_reactionID:r1407 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034900 +name: 3-(N-formyl)-formiminopyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate." [UM-BBD_reactionID:r1399] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r1399 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034901 +name: endosulfan hydroxyether dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-." [UM-BBD_reactionID:r1411] +xref: UM-BBD_reactionID:r1411 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034902 +name: endosulfan sulfate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite." [UM-BBD_reactionID:r1387] +xref: UM-BBD_reactionID:r1387 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0034903 +name: endosulfan ether monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O." [UM-BBD_reactionID:r1413] +xref: UM-BBD_reactionID:r1413 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034904 +name: 5-chloro-2-oxopent-4-enoate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate." [UM-BBD_reactionID:r1436] +xref: UM-BBD_reactionID:r1436 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034905 +name: 5-chloro-4-hydroxy-2-oxopentanate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde." [UM-BBD_reactionID:r1437] +xref: EC:4.1.3 +xref: UM-BBD_reactionID:r1437 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0034906 +name: N-isopropylaniline 1,2-dixoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine." [UM-BBD_reactionID:r0721] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0721 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034907 +name: acetanilide 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide." [UM-BBD_reactionID:r0723] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0723 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034908 +name: 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+." [UM-BBD_reactionID:r0724] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r0724 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034909 +name: 6-hydroxypseudooxynicotine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine." [UM-BBD_reactionID:r1441] +xref: EC:1.5.99.14 +xref: UM-BBD_reactionID:r1441 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0034910 +name: 6-hydroxy-3-succinoylpyridine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine." [UM-BBD_reactionID:r1442] +xref: UM-BBD_reactionID:r1442 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034911 +name: phthalate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+." [UM-BBD_reactionID:r1444] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r1444 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034912 +name: phthalate 3,4-cis-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+." [UM-BBD_reactionID:r1445] +xref: MetaCyc:RXN5F9-56 +xref: UM-BBD_reactionID:r1445 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0034914 +name: trinitrophenol hydride denitratase activity +namespace: molecular_function +def: "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP." [UM-BBD_reactionID:r1448] +synonym: "2,4,6-trinitrophenol hydride denitratase activity" EXACT [] +synonym: "TNP hydride denitratase activity" EXACT [] +xref: EC:1.7.99 +xref: UM-BBD_reactionID:r1448 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0034915 +name: 2-methylhexanoyl-CoA C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA." [UM-BBD_reactionID:r0927] +xref: EC:2.3.1 +xref: UM-BBD_reactionID:r0927 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034916 +name: 2-methylhexanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-." [UM-BBD_reactionID:r0928] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r0928 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034917 +name: 2-methylhex-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA." [UM-BBD_reactionID:r0929] +xref: UM-BBD_reactionID:r0929 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034918 +name: 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0930] +xref: UM-BBD_reactionID:r0930 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034919 +name: butyryl-CoA 2-C-propionyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA." [UM-BBD_reactionID:r0931] +xref: UM-BBD_reactionID:r0931 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034920 +name: pyrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene." [UM-BBD_reactionID:r0934] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0934 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034921 +name: cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-." [UM-BBD_reactionID:r0935] +xref: UM-BBD_reactionID:r0935 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034922 +name: 4,5-dihydroxypyrene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+." [UM-BBD_reactionID:r0936] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0936 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034923 +name: phenanthrene-4,5-dicarboxylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2." [UM-BBD_reactionID:r0937] +xref: UM-BBD_reactionID:r0937 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034924 +name: cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2." [UM-BBD_reactionID:r0940] +xref: UM-BBD_reactionID:r0940 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0034925 +name: pyrene 4,5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O." [UM-BBD_reactionID:r0941] +xref: UM-BBD_reactionID:r0941 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034926 +name: pyrene-4,5-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene." [UM-BBD_reactionID:r0942] +xref: UM-BBD_reactionID:r0942 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0034927 +name: pyrene 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O." [UM-BBD_reactionID:r0943] +xref: UM-BBD_reactionID:r0943 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034928 +name: 1-hydroxypyrene 6,7-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O." [UM-BBD_reactionID:r0946] +xref: UM-BBD_reactionID:r0946 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034929 +name: 1-hydroxypyrene 7,8-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O." [UM-BBD_reactionID:r0949] +xref: UM-BBD_reactionID:r0949 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034930 +name: 1-hydroxypyrene sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX." [UM-BBD_reactionID:r0952] +xref: UM-BBD_reactionID:r0952 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0034931 +name: 1-hydroxypyrene methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX." [UM-BBD_reactionID:r0953] +xref: UM-BBD_reactionID:r0953 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0034932 +name: 1-methoxypyrene 6,7-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O." [UM-BBD_reactionID:r0954] +xref: UM-BBD_reactionID:r0954 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034933 +name: 1-hydroxy-6-methoxypyrene methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX." [UM-BBD_reactionID:r0956] +xref: UM-BBD_reactionID:r0956 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0034934 +name: phenanthrene-4-carboxylate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate." [UM-BBD_reactionID:r0939] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0939 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034935 +name: tetrachlorobenzene dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+." [UM-BBD_reactionID:r0957] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0957 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034936 +name: 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+." [UM-BBD_reactionID:r0959] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r0959 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034937 +name: perchlorate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O." [UM-BBD_reactionID:r0980] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r0980 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034938 +name: pyrrole-2-carboxylate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O." [UM-BBD_reactionID:r0968] +xref: EC:1.14.14 +xref: UM-BBD_reactionID:r0968 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0034939 +name: 5-hydroxypyrrole-2-carboxylate tautomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate." [UM-BBD_reactionID:r0969] +xref: UM-BBD_reactionID:r0969 +is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups + +[Term] +id: GO:0034940 +name: 5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3." [UM-BBD_reactionID:r0984] +xref: UM-BBD_reactionID:r0984 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0034941 +name: pyrrole-2-carboxylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2." [UM-BBD_reactionID:r0970] +xref: EC:4.1.1.93 +xref: UM-BBD_reactionID:r0970 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034942 +name: cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi." [UM-BBD_reactionID:r0988] +xref: UM-BBD_reactionID:r0988 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034943 +name: trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi." [UM-BBD_reactionID:r0989] +xref: UM-BBD_reactionID:r0989 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0034944 +name: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+." [UM-BBD_reactionID:r0986] +xref: UM-BBD_reactionID:r0986 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0034945 +name: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA." [UM-BBD_reactionID:r0987] +xref: EC:2.3.1 +xref: UM-BBD_reactionID:r0987 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0034946 +name: 3-isopropylbut-3-enoyl-CoA thioesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH." [UM-BBD_reactionID:r0994] +xref: UM-BBD_reactionID:r0994 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0034947 +name: terephthalate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-." [UM-BBD_reactionID:r0321] +xref: UM-BBD_reactionID:r0321 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034948 +name: 2,6-dihydroxypseudooxynicotine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate." [UM-BBD_reactionID:r0482] +xref: EC:3.7.1 +xref: UM-BBD_reactionID:r0482 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0034949 +name: 1,1-dichloroethane reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl." [UM-BBD_reactionID:r1008] +xref: EC:1.97.1 +xref: UM-BBD_reactionID:r1008 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0034950 +name: phenylboronic acid monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3." [UM-BBD_reactionID:r1020] +xref: UM-BBD_reactionID:r1020 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0034951 +name: o-hydroxylaminobenzoate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate." [UM-BBD_reactionID:r1026] +xref: EC:5.4.99 +xref: MetaCyc:RXN-8846 +xref: UM-BBD_reactionID:r1026 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0034952 +name: malonate semialdehyde decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2." [UM-BBD_reactionID:r0266] +xref: UM-BBD_reactionID:r0266 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0034953 +name: perillyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA." [UM-BBD_reactionID:r1002] +xref: UM-BBD_reactionID:r1002 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0034954 +name: diphenyl ether 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether." [UM-BBD_reactionID:r1450] +xref: EC:1.14.12 +xref: UM-BBD_reactionID:r1450 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0034955 +name: 2,3-dihydroxydiphenyl ether dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol." [UM-BBD_reactionID:r1451] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1451 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034956 +name: diphenyl ether 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+." [UM-BBD_reactionID:r1453] +xref: EC:1.13.11 +xref: UM-BBD_reactionID:r1453 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0034957 +name: 3-nitrophenol nitroreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O." [UM-BBD_reactionID:r1495] +xref: UM-BBD_reactionID:r1495 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0034958 +name: aminohydroquinone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3." [UM-BBD_reactionID:r1497] +xref: EC:3.5.99 +xref: UM-BBD_reactionID:r1497 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0034959 +name: endothelin maturation +namespace: biological_process +def: "The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin." [GOC:BHF, GOC:rl] +is_a: GO:0016486 ! peptide hormone processing +relationship: part_of GO:0003100 ! regulation of systemic arterial blood pressure by endothelin +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15384 xsd:anyURI + +[Term] +id: GO:0034963 +name: box C/D snoRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript into a mature box C/D snoRNA." [GOC:mah] +is_a: GO:0033967 ! box C/D snoRNA metabolic process +is_a: GO:0043144 ! snoRNA processing + +[Term] +id: GO:0034964 +name: box H/ACA snoRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript into a mature box H/ACA snoRNA." [GOC:mah] +is_a: GO:0033979 ! box H/ACA snoRNA metabolic process +is_a: GO:0043144 ! snoRNA processing + +[Term] +id: GO:0034965 +name: intronic box C/D snoRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA." [GOC:mah] +is_a: GO:0031070 ! intronic snoRNA processing +is_a: GO:0034963 ! box C/D snoRNA processing + +[Term] +id: GO:0034966 +name: intronic box H/ACA snoRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA." [GOC:mah] +is_a: GO:0031070 ! intronic snoRNA processing +is_a: GO:0034964 ! box H/ACA snoRNA processing + +[Term] +id: GO:0034967 +name: Set3 complex +namespace: cellular_component +def: "A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p." [GOC:ds, PMID:11711434] +synonym: "HDAC3 complex" EXACT [] +synonym: "SET3C" EXACT [] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0034968 +name: histone lysine methylation +namespace: biological_process +def: "The modification of a histone by addition of one or more methyl groups to a lysine residue." [GOC:mah, GOC:pr] +is_a: GO:0016571 ! histone methylation +is_a: GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0034969 +name: histone arginine methylation +namespace: biological_process +def: "The modification of a histone by addition of a methyl group to an arginine residue." [GOC:mah] +is_a: GO:0016571 ! histone methylation +is_a: GO:0018216 ! peptidyl-arginine methylation + +[Term] +id: GO:0034970 +name: histone H3-R2 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone." [GOC:mah] +synonym: "histone H3 R2 methylation" EXACT [] +synonym: "histone H3R2me" EXACT [] +synonym: "histone lysine H3 R2 methylation" EXACT [] +is_a: GO:0034969 ! histone arginine methylation + +[Term] +id: GO:0034971 +name: histone H3-R17 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone." [GOC:mah] +synonym: "histone H3 R17 methylation" EXACT [] +synonym: "histone H3R17me" EXACT [] +synonym: "histone lysine H3 R17 methylation" EXACT [] +is_a: GO:0034969 ! histone arginine methylation + +[Term] +id: GO:0034972 +name: histone H3-R26 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone." [GOC:mah] +synonym: "histone H3 R26 methylation" EXACT [] +synonym: "histone H3R26me" EXACT [] +synonym: "histone lysine H3 R26 methylation" EXACT [] +is_a: GO:0034969 ! histone arginine methylation + +[Term] +id: GO:0034973 +name: Sid2-Mob1 complex +namespace: cellular_component +def: "A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex." [GOC:vw, PMID:10837231, PMID:15060149] +synonym: "Dbf2p-Mob1p complex" EXACT [] +synonym: "Sid2-Mob1 kinase complex" EXACT [] +synonym: "Sid2p-Mob1p complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034974 +name: Swi5-Swi2 complex +namespace: cellular_component +def: "A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching." [PMID:14663140] +comment: Note that this term refers to Schizosaccharomyces pombe Swi5 and Swi2, which should not be confused with the unrelated Saccharomyces Swi5p and Swi2p. +synonym: "Swi5 complex" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0034975 +name: protein folding in endoplasmic reticulum +namespace: biological_process +def: "A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)." [GOC:mah, GOC:vw] +synonym: "oxidative protein folding" EXACT [PMID:25091901] +synonym: "protein folding in ER" EXACT [] +is_a: GO:0006457 ! protein folding + +[Term] +id: GO:0034976 +name: response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:cjm, GOC:mah] +synonym: "cellular response to endoplasmic reticulum stress" EXACT [] +synonym: "ER stress response" EXACT [] +synonym: "response to ER stress" EXACT [] +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0034977 +name: ABIN2-NFKB1-MAP3K8 complex +namespace: cellular_component +def: "A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages." [PMID:15169888] +synonym: "ABIN2-NFKB1-TPL-1 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0034978 +name: PDX1-PBX1b-MRG1 complex +namespace: cellular_component +def: "A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes." [PMID:11279116, PMID:9710595] +synonym: "acinar cell-specific C complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034979 +name: NAD-dependent protein deacetylase activity +namespace: molecular_function +def: "Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD." [GOC:BHF, GOC:mah] +xref: Reactome:R-HSA-3371467 "SIRT1 deacetylates HSF1" +xref: Reactome:R-HSA-5211239 "SIRT1 deacetylates TAF1B in SL1 complex" +xref: Reactome:R-HSA-5685953 "SIRT6 deacetylates RBBP8" +xref: Reactome:R-HSA-5688289 "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2" +xref: Reactome:R-HSA-5688294 "SIRT5 deacetylates Cytochrome C" +xref: Reactome:R-HSA-9620532 "SIRT1,SIRT3 deacetylate FOXO3" +is_a: GO:0033558 ! protein deacetylase activity + +[Term] +id: GO:0034980 +name: FHL2-CREB complex +namespace: cellular_component +def: "A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation." [PMID:11046156] +is_a: GO:0033202 ! DNA helicase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034981 +name: FHL3-CREB complex +namespace: cellular_component +def: "A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation." [PMID:11046156] +is_a: GO:0033202 ! DNA helicase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0034982 +name: mitochondrial protein processing +namespace: biological_process +def: "The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import." [GOC:curators] +synonym: "mitochondrial protein modification" RELATED [] +is_a: GO:0016485 ! protein processing +is_a: GO:0044267 ! cellular protein metabolic process +intersection_of: GO:0016485 ! protein processing +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0034983 +name: peptidyl-lysine deacetylation +namespace: biological_process +def: "The removal of an acetyl group from an acetylated lysine residue in a peptide or protein." [GOC:BHF, GOC:mah] +synonym: "protein lysine acetylation" RELATED [] +is_a: GO:0006476 ! protein deacetylation +is_a: GO:0018205 ! peptidyl-lysine modification + +[Term] +id: GO:0034985 +name: Ecsit-NDUFAF1 complex +namespace: cellular_component +def: "Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed." [PMID:17344420] +is_a: GO:0098798 ! mitochondrial protein complex +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0034986 +name: iron chaperone activity +namespace: molecular_function +def: "Directly binding to and delivering iron ions to a target protein." [GOC:BHF, GOC:vk] +is_a: GO:0005506 ! iron ion binding +is_a: GO:0016530 ! metallochaperone activity + +[Term] +id: GO:0034987 +name: immunoglobulin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule." [GOC:BHF, GOC:vk] +synonym: "Fc receptor binding" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0034988 +name: Fc-gamma receptor I complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG." [GOC:BHF, GOC:vk] +is_a: GO:0034987 ! immunoglobulin receptor binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0034990 +name: nuclear mitotic cohesin complex +namespace: cellular_component +def: "A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex." [GOC:mah] +comment: Note that this term should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i. e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used. +is_a: GO:0000798 ! nuclear cohesin complex +is_a: GO:0030892 ! mitotic cohesin complex + +[Term] +id: GO:0034991 +name: nuclear meiotic cohesin complex +namespace: cellular_component +def: "A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex." [GOC:mah] +is_a: GO:0000798 ! nuclear cohesin complex +is_a: GO:0030893 ! meiotic cohesin complex + +[Term] +id: GO:0034992 +name: microtubule organizing center attachment site +namespace: cellular_component +def: "A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope." [GOC:mah, PMID:18692466] +comment: Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'. +synonym: "MAS" EXACT [] +synonym: "microtubule organising centre attachment site" EXACT [] +synonym: "MTOC attachment site" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005635 ! nuclear envelope + +[Term] +id: GO:0034993 +name: meiotic nuclear membrane microtubule tethering complex +namespace: cellular_component +def: "A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis." [GOC:mah, PMID:18692466] +synonym: "LINC complex" EXACT [] +synonym: "LInker of Nucleoskeleton and Cytoskeleton complex" EXACT [] +synonym: "SUN-KASH complex" EXACT [] +is_a: GO:0106094 ! nuclear membrane microtubule tethering complex +relationship: part_of GO:0034992 ! microtubule organizing center attachment site + +[Term] +id: GO:0034994 +name: microtubule organizing center attachment site organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches." [GOC:mah, PMID:18692466] +synonym: "MAS organization" EXACT [] +synonym: "microtubule organising centre attachment site organisation" RELATED [] +synonym: "MTOC attachment site organization" EXACT [] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0006998 ! nuclear envelope organization + +[Term] +id: GO:0034995 +name: SC5b-7 complex +namespace: cellular_component +def: "A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly." [PMID:10090939] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0034996 +name: RasGAP-Fyn-Lyn-Yes complex +namespace: cellular_component +def: "A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation." [PMID:1544885] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +synonym: "p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0034997 +name: alphav-beta5 integrin-vitronectin complex +namespace: cellular_component +def: "A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin." [PMID:1694173] +synonym: "ITGAV-ITGB5-VTN complex" NARROW [CORUM:3117] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0034998 +name: oligosaccharyltransferase I complex +namespace: cellular_component +def: "An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes." [PMID:15835887] +synonym: "OSTCI" EXACT [] +is_a: GO:0008250 ! oligosaccharyltransferase complex + +[Term] +id: GO:0034999 +name: oligosaccharyltransferase II complex +namespace: cellular_component +def: "An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes." [GOC:BHF, PMID:15835887] +synonym: "OSTCII" EXACT [] +is_a: GO:0008250 ! oligosaccharyltransferase complex + +[Term] +id: GO:0035000 +name: oligosaccharyltransferase III complex +namespace: cellular_component +def: "An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes." [PMID:15835887] +synonym: "OSTCIII" EXACT [] +is_a: GO:0008250 ! oligosaccharyltransferase complex + +[Term] +id: GO:0035001 +name: dorsal trunk growth, open tracheal system +namespace: biological_process +def: "Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system." [GOC:mtg_sensu, ISBN:0879694238] +synonym: "dorsal trunk growth" RELATED [] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035002 +name: liquid clearance, open tracheal system +namespace: biological_process +def: "The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system." [GOC:mtg_sensu, PMID:12571352] +synonym: "tracheal liquid clearance" EXACT [] +is_a: GO:0042045 ! epithelial fluid transport +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035003 +name: subapical complex +namespace: cellular_component +def: "The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells." [PMID:11752566, PMID:12500938] +synonym: "SAC" BROAD [] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0043296 ! apical junction complex + +[Term] +id: GO:0035004 +name: phosphatidylinositol 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring." [GOC:bf, PMID:10209156, PMID:9255069] +synonym: "phosphoinositide 3-kinase activity" EXACT [] +xref: Reactome:R-HSA-1433514 "Synthesis of PIP3 from PIP2 by PI3K" +xref: Reactome:R-HSA-2045911 "BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3" +xref: Reactome:R-HSA-9028519 "NTRK2-activated PI3K generates PIP3" +xref: Wikipedia:Phosphoinositide_3-kinase +is_a: GO:0016301 ! kinase activity +relationship: part_of GO:0046854 ! phosphatidylinositol phosphorylation + +[Term] +id: GO:0035005 +name: 1-phosphatidylinositol-4-phosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.154, RHEA:18373] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.154] +synonym: "C2-domain-containing phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.154] +synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] +synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] +synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] +synonym: "phosphatidylinositol-4-phosphate 3-kinase activity" EXACT [] +synonym: "type II phosphoinositide 3-kinase activity" RELATED [EC:2.7.1.154] +xref: EC:2.7.1.154 +xref: KEGG_REACTION:R05795 +xref: MetaCyc:2.7.1.154-RXN +xref: Reactome:R-HSA-1675928 "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane" +xref: Reactome:R-HSA-1676109 "PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane" +xref: Reactome:R-HSA-1676206 "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane" +xref: Reactome:R-HSA-8868072 "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2" +xref: RHEA:18373 +is_a: GO:0016307 ! phosphatidylinositol phosphate kinase activity +is_a: GO:0035004 ! phosphatidylinositol 3-kinase activity + +[Term] +id: GO:0035006 +name: melanization defense response +namespace: biological_process +def: "The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin." [GOC:bf, PMID:12408809] +synonym: "melanization defence response" EXACT [] +is_a: GO:0006582 ! melanin metabolic process +is_a: GO:0045087 ! innate immune response + +[Term] +id: GO:0035007 +name: regulation of melanization defense response +namespace: biological_process +def: "Any process that affects the rate, extent or location of the melanization defense response during injury or invasion." [GOC:bf] +synonym: "regulation of melanization defence response" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035006 ! melanization defense response +relationship: regulates GO:0035006 ! melanization defense response + +[Term] +id: GO:0035008 +name: positive regulation of melanization defense response +namespace: biological_process +def: "Any process that increases the rate or extent of the melanization defense response during injury or invasion." [GOC:bf] +synonym: "activation of melanization defense response" NARROW [] +synonym: "positive regulation of melanization defence response" EXACT [] +synonym: "stimulation of melanization defense response" NARROW [] +synonym: "up regulation of melanization defense response" EXACT [] +synonym: "up-regulation of melanization defense response" EXACT [] +synonym: "upregulation of melanization defense response" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0035007 ! regulation of melanization defense response +is_a: GO:0045089 ! positive regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035006 ! melanization defense response +relationship: positively_regulates GO:0035006 ! melanization defense response + +[Term] +id: GO:0035009 +name: negative regulation of melanization defense response +namespace: biological_process +def: "Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection." [GOC:bf, PMID:12408809] +synonym: "down regulation of melanization defense response" EXACT [] +synonym: "down-regulation of melanization defense response" EXACT [] +synonym: "downregulation of melanization defense response" EXACT [] +synonym: "inhibition of melanization defense response" NARROW [] +synonym: "negative regulation of melanization defence response" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0035007 ! regulation of melanization defense response +is_a: GO:0045824 ! negative regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035006 ! melanization defense response +relationship: negatively_regulates GO:0035006 ! melanization defense response + +[Term] +id: GO:0035010 +name: encapsulation of foreign target +namespace: biological_process +def: "Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization." [GO_REF:0000022, GOC:bf, PMID:11846478, PMID:12225920] +is_a: GO:0002252 ! immune effector process + +[Term] +id: GO:0035011 +name: melanotic encapsulation of foreign target +namespace: biological_process +def: "Formation of a multilayered, melanized sheath of cells around a foreign invader." [GOC:bf] +is_a: GO:0035006 ! melanization defense response +is_a: GO:0035010 ! encapsulation of foreign target + +[Term] +id: GO:0035012 +name: obsolete polytene chromosome, telomeric region +namespace: cellular_component +def: "OBSOLETE. The terminal region of a polytene chromosome." [GOC:bf] +comment: This term was obsoleted because it likely represents an assay for GO:1990707 nuclear subtelomeric heterochromatin. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19177 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0035013 +name: myosuppressin receptor activity +namespace: molecular_function +def: "Combining with the peptide myosuppressin to initiate a change in cell activity." [GOC:bf] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity + +[Term] +id: GO:0035014 +name: phosphatidylinositol 3-kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates." [GOC:bf, PMID:9255069] +comment: See also the molecular function term 'phosphoinositide 3-kinase activity ; GO:0035004'. +synonym: "phosphoinositide 3-kinase regulator activity" EXACT [] +synonym: "PI3K regulator activity" EXACT [] +is_a: GO:0019207 ! kinase regulator activity +relationship: has_part GO:0036313 ! phosphatidylinositol 3-kinase catalytic subunit binding +relationship: part_of GO:0043551 ! regulation of phosphatidylinositol 3-kinase activity +relationship: regulates GO:0035004 ! phosphatidylinositol 3-kinase activity + +[Term] +id: GO:0035015 +name: elongation of arista core +namespace: biological_process +def: "The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions." [GOC:bf, PMID:11404081] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0048800 ! antennal morphogenesis + +[Term] +id: GO:0035016 +name: elongation of arista lateral +namespace: biological_process +def: "The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions." [GOC:bf, PMID:11404081] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0048800 ! antennal morphogenesis + +[Term] +id: GO:0035017 +name: cuticle pattern formation +namespace: biological_process +def: "The regionalization process that gives rise to the patterns of cell differentiation in the cuticle." [GOC:bf] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0042335 ! cuticle development + +[Term] +id: GO:0035018 +name: adult chitin-based cuticle pattern formation +namespace: biological_process +def: "The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "adult cuticle pattern formation" BROAD [] +is_a: GO:0035017 ! cuticle pattern formation +relationship: part_of GO:0008365 ! adult chitin-based cuticle development + +[Term] +id: GO:0035019 +name: somatic stem cell population maintenance +namespace: biological_process +def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] +is_a: GO:0019827 ! stem cell population maintenance + +[Term] +id: GO:0035020 +name: regulation of Rac protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016601 ! Rac protein signal transduction +relationship: regulates GO:0016601 ! Rac protein signal transduction + +[Term] +id: GO:0035021 +name: negative regulation of Rac protein signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] +synonym: "down regulation of Rac protein signal transduction" EXACT [] +synonym: "down-regulation of Rac protein signal transduction" EXACT [] +synonym: "downregulation of Rac protein signal transduction" EXACT [] +synonym: "inhibition of Rac protein signal transduction" NARROW [] +is_a: GO:0035020 ! regulation of Rac protein signal transduction +is_a: GO:0046580 ! negative regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016601 ! Rac protein signal transduction +relationship: negatively_regulates GO:0016601 ! Rac protein signal transduction + +[Term] +id: GO:0035022 +name: positive regulation of Rac protein signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] +synonym: "activation of Rac protein signal transduction" NARROW [] +synonym: "stimulation of Rac protein signal transduction" NARROW [] +synonym: "up regulation of Rac protein signal transduction" EXACT [] +synonym: "up-regulation of Rac protein signal transduction" EXACT [] +synonym: "upregulation of Rac protein signal transduction" EXACT [] +is_a: GO:0035020 ! regulation of Rac protein signal transduction +is_a: GO:0046579 ! positive regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016601 ! Rac protein signal transduction +relationship: positively_regulates GO:0016601 ! Rac protein signal transduction + +[Term] +id: GO:0035023 +name: regulation of Rho protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007266 ! Rho protein signal transduction +relationship: regulates GO:0007266 ! Rho protein signal transduction + +[Term] +id: GO:0035024 +name: negative regulation of Rho protein signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] +synonym: "down regulation of Rho protein signal transduction" EXACT [] +synonym: "down-regulation of Rho protein signal transduction" EXACT [] +synonym: "downregulation of Rho protein signal transduction" EXACT [] +synonym: "inhibition of Rho protein signal transduction" NARROW [] +is_a: GO:0035023 ! regulation of Rho protein signal transduction +is_a: GO:0046580 ! negative regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007266 ! Rho protein signal transduction +relationship: negatively_regulates GO:0007266 ! Rho protein signal transduction + +[Term] +id: GO:0035025 +name: positive regulation of Rho protein signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] +synonym: "activation of Rho protein signal transduction" NARROW [] +synonym: "stimulation of Rho protein signal transduction" NARROW [] +synonym: "up regulation of Rho protein signal transduction" EXACT [] +synonym: "up-regulation of Rho protein signal transduction" EXACT [] +synonym: "upregulation of Rho protein signal transduction" EXACT [] +is_a: GO:0035023 ! regulation of Rho protein signal transduction +is_a: GO:0046579 ! positive regulation of Ras protein signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007266 ! Rho protein signal transduction +relationship: positively_regulates GO:0007266 ! Rho protein signal transduction + +[Term] +id: GO:0035026 +name: leading edge cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet." [GOC:bf] +is_a: GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0035027 +name: leading edge cell fate commitment +namespace: biological_process +def: "The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet." [GOC:bf] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0035026 ! leading edge cell differentiation + +[Term] +id: GO:0035028 +name: leading edge cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:bf] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0035027 ! leading edge cell fate commitment + +[Term] +id: GO:0035029 +name: dorsal closure, leading edge cell fate commitment +namespace: biological_process +def: "The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis." [GOC:bf] +is_a: GO:0035027 ! leading edge cell fate commitment +intersection_of: GO:0035027 ! leading edge cell fate commitment +intersection_of: part_of GO:0007391 ! dorsal closure +relationship: part_of GO:0046663 ! dorsal closure, leading edge cell differentiation + +[Term] +id: GO:0035032 +name: phosphatidylinositol 3-kinase complex, class III +namespace: cellular_component +def: "A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI)." [GOC:bf, PMID:9255069] +synonym: "class III PI3K complex" EXACT [] +synonym: "phosphoinositide 3-kinase complex, class III" EXACT [] +is_a: GO:0005942 ! phosphatidylinositol 3-kinase complex + +[Term] +id: GO:0035033 +name: histone deacetylase regulator activity +namespace: molecular_function +def: "Modulates the activity of histone deacetylase." [GOC:bf] +comment: See also the molecular function term 'histone deacetylase activity ; GO:0004407'. +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0042826 ! histone deacetylase binding +relationship: part_of GO:0031063 ! regulation of histone deacetylation +relationship: regulates GO:0004407 ! histone deacetylase activity + +[Term] +id: GO:0035034 +name: histone acetyltransferase regulator activity +namespace: molecular_function +def: "Modulates the activity of histone acetyltransferase." [GOC:bf] +comment: See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'. +synonym: "histone acetylase regulator activity" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0035035 ! histone acetyltransferase binding +relationship: part_of GO:0035065 ! regulation of histone acetylation +relationship: regulates GO:0004402 ! histone acetyltransferase activity + +[Term] +id: GO:0035035 +name: histone acetyltransferase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme histone acetyltransferase." [GOC:bf] +synonym: "histone acetylase binding" EXACT [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0035036 +name: sperm-egg recognition +namespace: biological_process +def: "The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization." [GOC:bf] +is_a: GO:0009988 ! cell-cell recognition +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035037 +name: sperm entry +namespace: biological_process +def: "An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur." [GOC:bf, PMID:9630751] +is_a: GO:0006897 ! endocytosis +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035038 +name: female pronucleus assembly +namespace: biological_process +def: "Assembly of the haploid nucleus of the unfertilized egg." [GOC:bf, ISBN:0582227089] +synonym: "female pronucleus assembly" RELATED [GOC:dph] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0022414 ! reproductive process +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035039 +name: male pronucleus assembly +namespace: biological_process +def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001] +synonym: "male pronucleus formation" RELATED [GOC:dph] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0022414 ! reproductive process +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035040 +name: sperm nuclear envelope removal +namespace: biological_process +def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051081 ! nuclear envelope disassembly +relationship: part_of GO:0035039 ! male pronucleus assembly + +[Term] +id: GO:0035041 +name: sperm chromatin decondensation +namespace: biological_process +def: "Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus." [GOC:bf, PMID:11735001] +is_a: GO:0006325 ! chromatin organization +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0035039 ! male pronucleus assembly + +[Term] +id: GO:0035042 +name: fertilization, exchange of chromosomal proteins +namespace: biological_process +def: "Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity." [GOC:bf, PMID:11735001] +synonym: "sperm-specific histone exchange" EXACT [] +synonym: "sperm-specific histone replacement" EXACT [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0043486 ! histone exchange +relationship: part_of GO:0035041 ! sperm chromatin decondensation + +[Term] +id: GO:0035043 +name: male pronuclear envelope synthesis +namespace: biological_process +def: "Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation." [GOC:bf, PMID:11735001] +is_a: GO:0018985 ! pronuclear envelope synthesis +relationship: part_of GO:0035039 ! male pronucleus assembly + +[Term] +id: GO:0035044 +name: sperm aster formation +namespace: biological_process +def: "Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei." [GOC:bf, ISBN:0879694238] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035045 +name: sperm plasma membrane disassembly +namespace: biological_process +def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238] +synonym: "sperm plasma membrane breakdown" EXACT [] +synonym: "sperm plasma membrane catabolism" EXACT [] +synonym: "sperm plasma membrane degradation" EXACT [] +is_a: GO:0007009 ! plasma membrane organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030397 ! membrane disassembly +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035046 +name: pronuclear migration +namespace: biological_process +def: "The directed movement of the male and female pronuclei towards each other prior to their fusion." [GOC:bf, PMID:9199363] +is_a: GO:0007097 ! nuclear migration +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035047 +name: centrosomal and pronuclear rotation +namespace: biological_process +def: "The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion." [GOC:bf, ISBN:087969307X, PMID:10085292] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0035048 +name: obsolete splicing factor protein import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane." [GOC:bf] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "splicing factor protein transport from cytoplasm to nucleus" EXACT [] +synonym: "splicing factor protein-nucleus import" EXACT [] +is_obsolete: true +consider: GO:0006606 + +[Term] +id: GO:0035049 +name: juvenile hormone acid methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to juvenile hormone acid." [GOC:bf] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0035050 +name: embryonic heart tube development +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators] +is_a: GO:0035295 ! tube development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0007507 ! heart development +relationship: part_of GO:0048568 ! embryonic organ development + +[Term] +id: GO:0035051 +name: cardiocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf] +synonym: "cardiac cell differentiation" EXACT [] +synonym: "heart cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0035052 +name: dorsal vessel aortic cell fate commitment +namespace: biological_process +def: "The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12397110] +is_a: GO:0060581 ! cell fate commitment involved in pattern specification +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0035054 ! embryonic heart tube anterior/posterior pattern specification + +[Term] +id: GO:0035053 +name: dorsal vessel heart proper cell fate commitment +namespace: biological_process +def: "The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12397110] +is_a: GO:0060581 ! cell fate commitment involved in pattern specification +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0035054 ! embryonic heart tube anterior/posterior pattern specification + +[Term] +id: GO:0035054 +name: embryonic heart tube anterior/posterior pattern specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta." [GOC:bf, PMID:12435360] +is_a: GO:0009952 ! anterior/posterior pattern specification +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0035059 +name: RCAF complex +namespace: cellular_component +def: "A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4." [GOC:bf, PMID:10591219] +synonym: "replication-coupling assembly factor complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0035060 +name: brahma complex +namespace: cellular_component +def: "A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof." [GOC:bhm, PMID:10809665, PMID:12482982] +synonym: "BRM complex" EXACT [] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex + +[Term] +id: GO:0035061 +name: interchromatin granule +namespace: cellular_component +def: "A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439] +synonym: "ICG" EXACT [] +xref: NIF_Subcellular:sao1049471211 +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0035062 +name: omega speckle +namespace: cellular_component +def: "A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439] +is_a: GO:0016607 ! nuclear speck + +[Term] +id: GO:0035063 +name: nuclear speck organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized." [GOC:bf, GOC:curators] +comment: See also the cellular component term 'nuclear speck ; GO:0016607'. +synonym: "nuclear speck organisation" EXACT [] +synonym: "nuclear speck organization and biogenesis" RELATED [GOC:mah] +synonym: "nuclear speckle assembly" NARROW [GOC:mah] +synonym: "nuclear speckle organization" EXACT [] +is_a: GO:0030575 ! nuclear body organization + +[Term] +id: GO:0035064 +name: methylated histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:bf, PMID:14585615] +is_a: GO:0042393 ! histone binding +is_a: GO:0140034 ! methylation-dependent protein binding + +[Term] +id: GO:0035065 +name: regulation of histone acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016573 ! histone acetylation +relationship: regulates GO:0016573 ! histone acetylation + +[Term] +id: GO:0035066 +name: positive regulation of histone acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] +synonym: "activation of histone acetylation" NARROW [] +synonym: "stimulation of histone acetylation" NARROW [] +synonym: "up regulation of histone acetylation" EXACT [] +synonym: "up-regulation of histone acetylation" EXACT [] +synonym: "upregulation of histone acetylation" EXACT [] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0035065 ! regulation of histone acetylation +is_a: GO:2000758 ! positive regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016573 ! histone acetylation +relationship: positively_regulates GO:0016573 ! histone acetylation + +[Term] +id: GO:0035067 +name: negative regulation of histone acetylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] +synonym: "down regulation of histone acetylation" EXACT [] +synonym: "down-regulation of histone acetylation" EXACT [] +synonym: "downregulation of histone acetylation" EXACT [] +synonym: "inhibition of histone acetylation" NARROW [] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0035065 ! regulation of histone acetylation +is_a: GO:2000757 ! negative regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016573 ! histone acetylation +relationship: negatively_regulates GO:0016573 ! histone acetylation + +[Term] +id: GO:0035069 +name: larval midgut histolysis +namespace: biological_process +def: "The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly." [GOC:bf, GOC:dph, GOC:mtg_apoptosis, PMID:9409683] +synonym: "larval midgut regression" EXACT [] +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0007552 ! metamorphosis +relationship: part_of GO:0048707 ! instar larval or pupal morphogenesis + +[Term] +id: GO:0035070 +name: salivary gland histolysis +namespace: biological_process +def: "The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly." [GOC:bf, GOC:dph, GOC:mtg_apoptosis, PMID:9409683] +synonym: "salivary gland regression" EXACT [] +is_a: GO:0007435 ! salivary gland morphogenesis +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0007552 ! metamorphosis +relationship: part_of GO:0048707 ! instar larval or pupal morphogenesis + +[Term] +id: GO:0035071 +name: salivary gland cell autophagic cell death +namespace: biological_process +def: "The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis." [GOC:bf, GOC:mtg_apoptosis, PMID:10882130] +synonym: "autophagic cell death of salivary gland cells" EXACT [] +synonym: "programmed cell death of salivary gland cells by autophagy" EXACT [] +synonym: "salivary gland cell death" EXACT [] +synonym: "salivary gland cell programmed cell death by autophagy" EXACT [] +is_a: GO:0010623 ! programmed cell death involved in cell development +is_a: GO:0048102 ! autophagic cell death +relationship: part_of GO:0035070 ! salivary gland histolysis + +[Term] +id: GO:0035072 +name: ecdysone-mediated induction of salivary gland cell autophagic cell death +namespace: biological_process +def: "Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis." [GOC:bf] +synonym: "ecdysone-mediated induction of autophagic cell death of salivary gland cells" EXACT [] +synonym: "ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy" EXACT [] +synonym: "ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy" EXACT [] +is_a: GO:0035078 ! induction of programmed cell death by ecdysone +relationship: part_of GO:0035071 ! salivary gland cell autophagic cell death + +[Term] +id: GO:0035073 +name: pupariation +namespace: biological_process +def: "The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis." [GOC:bf, ISBN:0879694238, PMID:9409683] +synonym: "puparium biosynthesis" EXACT [] +synonym: "puparium formation" EXACT [] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0035210 ! prepupal development + +[Term] +id: GO:0035074 +name: pupation +namespace: biological_process +def: "The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period." [GOC:bf, ISBN:0582227089, ISBN:0879694238] +synonym: "head eversion" EXACT [] +synonym: "prepupal-pupal transition" EXACT [] +xref: Wikipedia:Pupa +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0035209 ! pupal development + +[Term] +id: GO:0035075 +name: response to ecdysone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus." [GOC:bf] +is_a: GO:0009725 ! response to hormone +is_a: GO:0036314 ! response to sterol +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0035076 +name: ecdysone receptor-mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex." [GOC:bf] +synonym: "ecdysone receptor-mediated signalling pathway" EXACT [] +is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway +relationship: part_of GO:0071390 ! cellular response to ecdysone + +[Term] +id: GO:0035077 +name: ecdysone-mediated polytene chromosome puffing +namespace: biological_process +def: "The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation." [GOC:bf, PMID:12543962] +is_a: GO:0035079 ! polytene chromosome puffing +relationship: part_of GO:0071390 ! cellular response to ecdysone + +[Term] +id: GO:0035078 +name: induction of programmed cell death by ecdysone +namespace: biological_process +def: "Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death." [GOC:bf] +is_a: GO:0035081 ! induction of programmed cell death by hormones +relationship: part_of GO:0035075 ! response to ecdysone + +[Term] +id: GO:0035079 +name: polytene chromosome puffing +namespace: biological_process +def: "The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals." [GOC:bf, PMID:12543962] +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0035080 +name: heat shock-mediated polytene chromosome puffing +namespace: biological_process +def: "The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus." [GOC:bf, PMID:12543962] +is_a: GO:0034605 ! cellular response to heat +is_a: GO:0035079 ! polytene chromosome puffing + +[Term] +id: GO:0035081 +name: induction of programmed cell death by hormones +namespace: biological_process +def: "Any process induced by hormones that directly activates any of the steps required for programmed cell death." [GOC:bf] +is_a: GO:0012502 ! induction of programmed cell death + +[Term] +id: GO:0035082 +name: axoneme assembly +namespace: biological_process +alt_id: GO:0035083 +alt_id: GO:0035084 +def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "axoneme biogenesis" RELATED [GOC:mah] +synonym: "ciliary axoneme assembly" EXACT [] +synonym: "cilium axoneme assembly" EXACT [] +synonym: "cilium axoneme biogenesis" RELATED [GOC:mah] +synonym: "flagellar axoneme assembly" EXACT [] +synonym: "flagellum axoneme assembly" EXACT [] +is_a: GO:0001578 ! microtubule bundle formation +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0060271 ! cilium assembly + +[Term] +id: GO:0035087 +name: siRNA loading onto RISC involved in RNA interference +namespace: biological_process +def: "The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference." [GOC:bf, GOC:mah, PMID:14512631] +synonym: "RNA interference, siRNA loading onto RISC" EXACT [GOC:mah] +is_a: GO:0070922 ! small RNA loading onto RISC +relationship: part_of GO:0016246 ! RNA interference + +[Term] +id: GO:0035088 +name: establishment or maintenance of apical/basal cell polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components." [GOC:bf, GOC:mah, PMID:10934483] +is_a: GO:0061245 ! establishment or maintenance of bipolar cell polarity + +[Term] +id: GO:0035089 +name: establishment of apical/basal cell polarity +namespace: biological_process +def: "The specification and formation of the polarity of a cell along its apical/basal axis." [GOC:bf] +is_a: GO:0035088 ! establishment or maintenance of apical/basal cell polarity +is_a: GO:0061162 ! establishment of monopolar cell polarity + +[Term] +id: GO:0035090 +name: maintenance of apical/basal cell polarity +namespace: biological_process +def: "Retaining the established polarization of a cell along its apical/basal axis." [GOC:bf] +is_a: GO:0030011 ! maintenance of cell polarity +is_a: GO:0035088 ! establishment or maintenance of apical/basal cell polarity + +[Term] +id: GO:0035091 +name: phosphatidylinositol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, ISBN:0198506732, PMID:11395417] +synonym: "phosphoinositide binding" EXACT [] +is_a: GO:0005543 ! phospholipid binding + +[Term] +id: GO:0035092 +name: sperm chromatin condensation +namespace: biological_process +def: "The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication." [GOC:bf, PMID:11735001] +is_a: GO:0006323 ! DNA packaging +is_a: GO:0006325 ! chromatin organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007289 ! spermatid nucleus differentiation + +[Term] +id: GO:0035093 +name: spermatogenesis, exchange of chromosomal proteins +namespace: biological_process +def: "The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin." [GOC:bf, PMID:11735001] +synonym: "somatic histone exchange" EXACT [] +synonym: "somatic histone replacement" RELATED [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0043486 ! histone exchange +relationship: part_of GO:0035092 ! sperm chromatin condensation + +[Term] +id: GO:0035094 +name: response to nicotine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus." [GOC:bf, GOC:ef, ISBN:0198506732, ISBN:0582227089] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0035095 +name: behavioral response to nicotine +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus." [GOC:bf, ISBN:0198506732] +synonym: "behavioural response to nicotine" EXACT [] +is_a: GO:0030534 ! adult behavior +relationship: part_of GO:0035094 ! response to nicotine + +[Term] +id: GO:0035096 +name: larval midgut cell programmed cell death +namespace: biological_process +def: "The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ." [GOC:bf, GOC:mtg_apoptosis] +synonym: "larval midgut cell death" EXACT [] +synonym: "programmed cell death of larval midgut cells" EXACT [] +is_a: GO:0010623 ! programmed cell death involved in cell development +relationship: part_of GO:0035069 ! larval midgut histolysis + +[Term] +id: GO:0035097 +name: histone methyltransferase complex +namespace: cellular_component +def: "A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins." [GOC:bf] +subset: goslim_pir +is_a: GO:0034708 ! methyltransferase complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0035098 +name: ESC/E(Z) complex +namespace: cellular_component +def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375] +synonym: "Extra Sex Combs/Enhancer of Zeste complex" EXACT [] +synonym: "PRC2 complex" EXACT [GOC:sp, PMID:20064375] +is_a: GO:0031519 ! PcG protein complex +is_a: GO:0035097 ! histone methyltransferase complex + +[Term] +id: GO:0035099 +name: hemocyte migration +namespace: biological_process +def: "The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo." [GOC:bf, GOC:mtg_sensu, PMID:12885551] +synonym: "arthropod blood cell migration" EXACT [] +synonym: "hemocyte cell migration" EXACT [] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0035162 ! embryonic hemopoiesis + +[Term] +id: GO:0035100 +name: ecdysone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting." [GOC:bf, ISBN:0198506732, ISBN:0582227089] +is_a: GO:0032934 ! sterol binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0035101 +name: FACT complex +namespace: cellular_component +def: "An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer." [GOC:bf, GOC:expert_ks, GOC:expert_ras, GOC:expert_tf, GOC:krc, PMID:12934006, PMID:12934007, PMID:16678108] +synonym: "Facilitates chromatin transcription complex" EXACT [] +is_a: GO:0008023 ! transcription elongation factor complex + +[Term] +id: GO:0035102 +name: PRC1 complex +namespace: cellular_component +def: "A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling." [GOC:bf, PMID:10412979] +comment: In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner. +synonym: "Polycomb repressive complex 1" EXACT [] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +is_a: GO:0031519 ! PcG protein complex + +[Term] +id: GO:0035103 +name: sterol regulatory element binding protein cleavage +namespace: biological_process +alt_id: GO:0006992 +def: "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids." [GOC:bf, GOC:vw, PMID:12923525] +synonym: "SREBP cleavage" EXACT [] +synonym: "sterol depletion response, SREBP cleavage" EXACT [] +synonym: "sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway" NARROW [GOC:vw] +is_a: GO:0016485 ! protein processing +is_a: GO:0044267 ! cellular protein metabolic process +relationship: part_of GO:0032933 ! SREBP signaling pathway + +[Term] +id: GO:0035105 +name: obsolete sterol regulatory element binding protein import into nucleus +namespace: biological_process +alt_id: GO:0006993 +def: "OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, GOC:vw, PMID:12923525] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "SREBP import into nucleus" EXACT [GOC:mah] +synonym: "SREBP import into nucleus involved in sterol depletion response" EXACT [GOC:mah] +synonym: "SREBP nuclear translocation" NARROW [GOC:mah] +synonym: "sterol depletion response, SREBP import into nucleus" EXACT [GOC:mah] +synonym: "sterol depletion response, SREBP nuclear translocation" NARROW [GOC:mah] +synonym: "sterol depletion response, sterol regulatory element binding protein import into nucleus" EXACT [] +synonym: "sterol depletion response, sterol regulatory element binding protein nuclear translocation" NARROW [GOC:dph, GOC:mah, GOC:tb] +synonym: "sterol regulatory element binding protein import into nucleus involved in sterol depletion response" NARROW [GOC:vw] +synonym: "sterol regulatory element binding protein nuclear translocation" NARROW [GOC:mah] +synonym: "sterol regulatory element binding protein nuclear translocation involved in sterol depletion response" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0006606 +consider: GO:0042306 + +[Term] +id: GO:0035106 +name: operant conditioning +namespace: biological_process +def: "Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior." [PMID:14662373] +synonym: "instrumental conditioning" EXACT [] +xref: Wikipedia:Operant_conditioning +is_a: GO:0007612 ! learning + +[Term] +id: GO:0035107 +name: appendage morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048736 ! appendage development + +[Term] +id: GO:0035108 +name: limb morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping." [UBERON:0002101] +synonym: "limb bud morphogenesis" NARROW [GOC:dph] +is_a: GO:0035107 ! appendage morphogenesis +relationship: part_of GO:0060173 ! limb development + +[Term] +id: GO:0035109 +name: obsolete imaginal disc-derived limb morphogenesis +namespace: biological_process +def: "OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +comment: This term was made obsolete because the term 'limb' is not widely used in the insect community. In GO, 'limb' is used to describe the vertebrate hindlimbs and forelimbs. +synonym: "imaginal disc-derived limb morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0035114 + +[Term] +id: GO:0035110 +name: obsolete leg morphogenesis +namespace: biological_process +def: "OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands." [GOC:bf, ISBN:0198612001] +comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. +synonym: "leg morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0007480 +consider: GO:0035108 +consider: GO:0035137 + +[Term] +id: GO:0035111 +name: obsolete leg joint morphogenesis +namespace: biological_process +def: "OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur." [GOC:bf, ISBN:0582227089, PMID:12051824] +comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. +synonym: "leg joint morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0016348 +consider: GO:0036023 + +[Term] +id: GO:0035112 +name: genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf] +synonym: "genital morphogenesis" RELATED [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048806 ! genitalia development + +[Term] +id: GO:0035113 +name: embryonic appendage morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] +is_a: GO:0035107 ! appendage morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis + +[Term] +id: GO:0035114 +name: imaginal disc-derived appendage morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism." [GOC:mtg_sensu, ISBN:0582227089] +is_a: GO:0035107 ! appendage morphogenesis +relationship: part_of GO:0048737 ! imaginal disc-derived appendage development + +[Term] +id: GO:0035115 +name: embryonic forelimb morphogenesis +namespace: biological_process +alt_id: GO:0035117 +def: "The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [ISBN:0198612001] +synonym: "embryonic arm morphogenesis" NARROW [GOC:bf, GOC:cjm] +is_a: GO:0030326 ! embryonic limb morphogenesis +is_a: GO:0035136 ! forelimb morphogenesis + +[Term] +id: GO:0035116 +name: embryonic hindlimb morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal." [ISBN:0198612001] +is_a: GO:0030326 ! embryonic limb morphogenesis +is_a: GO:0035137 ! hindlimb morphogenesis + +[Term] +id: GO:0035118 +name: embryonic pectoral fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0035113 ! embryonic appendage morphogenesis +is_a: GO:0035138 ! pectoral fin morphogenesis + +[Term] +id: GO:0035119 +name: embryonic pelvic fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0035113 ! embryonic appendage morphogenesis +is_a: GO:0035139 ! pelvic fin morphogenesis + +[Term] +id: GO:0035120 +name: post-embryonic appendage morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0035107 ! appendage morphogenesis + +[Term] +id: GO:0035121 +name: obsolete tail morphogenesis +namespace: biological_process +def: "OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals." [ISBN:0198612001] +comment: This term was made obsolete because 'tail' has different meanings in different organisms, and is therefore not a useful grouping term. +synonym: "tail morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0003002 +consider: GO:0036342 +consider: GO:0048809 + +[Term] +id: GO:0035122 +name: embryonic medial fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh] +synonym: "embryonic unpaired fin morphogenesis" EXACT [] +is_a: GO:0035113 ! embryonic appendage morphogenesis +is_a: GO:0035141 ! medial fin morphogenesis + +[Term] +id: GO:0035123 +name: embryonic dorsal fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh] +is_a: GO:0035122 ! embryonic medial fin morphogenesis +is_a: GO:0035142 ! dorsal fin morphogenesis + +[Term] +id: GO:0035124 +name: embryonic caudal fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion." [GOC:dgh] +is_a: GO:0035122 ! embryonic medial fin morphogenesis +is_a: GO:0035143 ! caudal fin morphogenesis + +[Term] +id: GO:0035125 +name: embryonic anal fin morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh] +is_a: GO:0035122 ! embryonic medial fin morphogenesis +is_a: GO:0035144 ! anal fin morphogenesis + +[Term] +id: GO:0035126 +name: post-embryonic genitalia morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized." [GOC:bf] +synonym: "post-embryonic genital morphogenesis" RELATED [] +is_a: GO:0035112 ! genitalia morphogenesis +is_a: GO:0048563 ! post-embryonic animal organ morphogenesis + +[Term] +id: GO:0035127 +name: post-embryonic limb morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping." [ISBN:0395825172] +is_a: GO:0035108 ! limb morphogenesis +is_a: GO:0035120 ! post-embryonic appendage morphogenesis + +[Term] +id: GO:0035128 +name: post-embryonic forelimb morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism." [GOC:bf] +is_a: GO:0035127 ! post-embryonic limb morphogenesis +is_a: GO:0035136 ! forelimb morphogenesis + +[Term] +id: GO:0035129 +name: post-embryonic hindlimb morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized." [GOC:bf] +is_a: GO:0035127 ! post-embryonic limb morphogenesis +is_a: GO:0035137 ! hindlimb morphogenesis + +[Term] +id: GO:0035130 +name: post-embryonic pectoral fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +is_a: GO:0035138 ! pectoral fin morphogenesis + +[Term] +id: GO:0035131 +name: post-embryonic pelvic fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +is_a: GO:0035139 ! pelvic fin morphogenesis + +[Term] +id: GO:0035132 +name: post-embryonic medial fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh] +synonym: "post-embryonic unpaired fin morphogenesis" EXACT [] +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +is_a: GO:0035141 ! medial fin morphogenesis + +[Term] +id: GO:0035133 +name: post-embryonic caudal fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion." [GOC:dgh] +is_a: GO:0035132 ! post-embryonic medial fin morphogenesis +is_a: GO:0035143 ! caudal fin morphogenesis + +[Term] +id: GO:0035134 +name: post-embryonic dorsal fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh] +is_a: GO:0035132 ! post-embryonic medial fin morphogenesis +is_a: GO:0035142 ! dorsal fin morphogenesis + +[Term] +id: GO:0035135 +name: post-embryonic anal fin morphogenesis +namespace: biological_process +def: "The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh] +is_a: GO:0035132 ! post-embryonic medial fin morphogenesis +is_a: GO:0035144 ! anal fin morphogenesis + +[Term] +id: GO:0035136 +name: forelimb morphogenesis +namespace: biological_process +alt_id: GO:0035140 +def: "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [GOC:go_curators] +synonym: "arm morphogenesis" NARROW [GOC:bf, GOC:cjm] +is_a: GO:0035108 ! limb morphogenesis + +[Term] +id: GO:0035137 +name: hindlimb morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hindlimb are generated and organized." [GOC:go_curators] +is_a: GO:0035108 ! limb morphogenesis + +[Term] +id: GO:0035138 +name: pectoral fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0033334 ! fin morphogenesis +relationship: part_of GO:0033339 ! pectoral fin development + +[Term] +id: GO:0035139 +name: pelvic fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion." [GOC:dgh] +is_a: GO:0033334 ! fin morphogenesis +relationship: part_of GO:0033340 ! pelvic fin development + +[Term] +id: GO:0035141 +name: medial fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming." [GOC:dgh] +synonym: "median fin morphogenesis" EXACT [] +synonym: "unpaired fin morphogenesis" EXACT [] +is_a: GO:0033334 ! fin morphogenesis +relationship: part_of GO:0033338 ! medial fin development + +[Term] +id: GO:0035142 +name: dorsal fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins." [GOC:dgh] +is_a: GO:0035141 ! medial fin morphogenesis +relationship: part_of GO:0033337 ! dorsal fin development + +[Term] +id: GO:0035143 +name: caudal fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion." [GOC:dgh] +is_a: GO:0035141 ! medial fin morphogenesis +relationship: part_of GO:0033336 ! caudal fin development + +[Term] +id: GO:0035144 +name: anal fin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming." [GOC:dgh] +is_a: GO:0035141 ! medial fin morphogenesis +relationship: part_of GO:0033335 ! anal fin development + +[Term] +id: GO:0035145 +name: exon-exon junction complex +namespace: cellular_component +def: "A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay." [PMID:11532962, PMID:11743026] +synonym: "EJC" EXACT [] +synonym: "exon junction complex" EXACT [GOC:dph] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0035146 +name: tube fusion +namespace: biological_process +def: "The joining of specific branches of a tubular system to form a continuous network." [GOC:bf] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0048754 ! branching morphogenesis of an epithelial tube + +[Term] +id: GO:0035147 +name: branch fusion, open tracheal system +namespace: biological_process +def: "Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint." [GOC:mtg_sensu, PMID:14570584] +synonym: "tracheal branch fusion" EXACT [] +is_a: GO:0035146 ! tube fusion +relationship: part_of GO:0060446 ! branching involved in open tracheal system development + +[Term] +id: GO:0035148 +name: tube formation +namespace: biological_process +def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf] +synonym: "lumen formation in an anatomical structure" RELATED [GOC:dph, GOC:mah] +synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035239 ! tube morphogenesis + +[Term] +id: GO:0035149 +name: lumen formation, open tracheal system +namespace: biological_process +def: "Creation of the central hole of a tube in an open tracheal system through which gases flow." [GOC:bf, GOC:mtg_sensu] +synonym: "tracheal lumen formation" EXACT [] +is_a: GO:0035148 ! tube formation +is_a: GO:0035152 ! regulation of tube architecture, open tracheal system + +[Term] +id: GO:0035150 +name: regulation of tube size +namespace: biological_process +def: "Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes." [PMID:10887083] +is_a: GO:0090066 ! regulation of anatomical structure size + +[Term] +id: GO:0035151 +name: regulation of tube size, open tracheal system +namespace: biological_process +def: "Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape." [GOC:mtg_sensu, PMID:10887083, PMID:12930776, PMID:12973360] +synonym: "regulation of tracheal tube size" EXACT [] +is_a: GO:0035150 ! regulation of tube size +is_a: GO:0035152 ! regulation of tube architecture, open tracheal system +intersection_of: GO:0035150 ! regulation of tube size +intersection_of: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035152 +name: regulation of tube architecture, open tracheal system +namespace: biological_process +def: "Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network." [GOC:mtg_sensu, PMID:14570584] +synonym: "regulation of tracheal tube architecture" EXACT [] +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035153 +name: epithelial cell type specification, open tracheal system +namespace: biological_process +def: "Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions." [GOC:mtg_sensu, PMID:10684581, PMID:11063940] +synonym: "tracheal cell type specification" BROAD [] +synonym: "tracheal epithelial cell type specification" EXACT [] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035154 +name: terminal cell fate specification, open tracheal system +namespace: biological_process +def: "The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange." [GOC:mtg_sensu, PMID:10684581, PMID:11063940] +synonym: "terminal cell fate specification" EXACT [] +is_a: GO:0035153 ! epithelial cell type specification, open tracheal system + +[Term] +id: GO:0035155 +name: negative regulation of terminal cell fate specification, open tracheal system +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [GOC:mtg_sensu, PMID:10684581] +synonym: "down regulation of terminal cell fate specification" EXACT [] +synonym: "down-regulation of terminal cell fate specification" EXACT [] +synonym: "downregulation of terminal cell fate specification" EXACT [] +synonym: "inhibition of terminal cell fate specification" NARROW [] +synonym: "negative regulation of terminal cell fate specification" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035154 ! terminal cell fate specification, open tracheal system +relationship: negatively_regulates GO:0035154 ! terminal cell fate specification, open tracheal system + +[Term] +id: GO:0035156 +name: fusion cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion." [PMID:11063940] +is_a: GO:0035153 ! epithelial cell type specification, open tracheal system + +[Term] +id: GO:0035157 +name: negative regulation of fusion cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [PMID:10684581] +synonym: "down regulation of fusion cell fate specification" EXACT [] +synonym: "down-regulation of fusion cell fate specification" EXACT [] +synonym: "downregulation of fusion cell fate specification" EXACT [] +synonym: "inhibition of fusion cell fate specification" NARROW [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035156 ! fusion cell fate specification +relationship: negatively_regulates GO:0035156 ! fusion cell fate specification + +[Term] +id: GO:0035158 +name: regulation of tube diameter, open tracheal system +namespace: biological_process +def: "Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size." [GOC:mtg_sensu, PMID:14570584] +synonym: "regulation of tracheal tube diameter" EXACT [] +synonym: "tracheal tube dilation" NARROW [] +synonym: "tracheal tube expansion" NARROW [] +is_a: GO:0035159 ! regulation of tube length, open tracheal system +is_a: GO:0035296 ! regulation of tube diameter + +[Term] +id: GO:0035159 +name: regulation of tube length, open tracheal system +namespace: biological_process +def: "Ensuring that a tube in an open tracheal system is of the correct length." [GOC:bf, GOC:mtg_sensu] +synonym: "regulation of tracheal tube length" EXACT [] +synonym: "tracheal tube elongation" NARROW [] +is_a: GO:0035151 ! regulation of tube size, open tracheal system + +[Term] +id: GO:0035160 +name: maintenance of epithelial integrity, open tracheal system +namespace: biological_process +def: "Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process." [GOC:mtg_sensu, PMID:10694415, PMID:14681183] +synonym: "maintenance of tracheal epithelial integrity" EXACT [] +is_a: GO:0010669 ! epithelial structure maintenance +is_a: GO:0035152 ! regulation of tube architecture, open tracheal system + +[Term] +id: GO:0035161 +name: imaginal disc lineage restriction +namespace: biological_process +def: "Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf, PMID:10625531, PMID:9374402] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0007447 ! imaginal disc pattern formation + +[Term] +id: GO:0035162 +name: embryonic hemopoiesis +namespace: biological_process +def: "The stages of blood cell formation that take place within the embryo." [GOC:bf] +synonym: "embryonic haematopoiesis" EXACT [] +synonym: "embryonic haemopoiesis" EXACT [] +synonym: "embryonic hematopoiesis" EXACT [] +is_a: GO:0030097 ! hemopoiesis +is_a: GO:0048568 ! embryonic organ development + +[Term] +id: GO:0035163 +name: embryonic hemocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu, PMID:14602069] +synonym: "embryonic arthropod blood cell differentiation" EXACT [] +synonym: "embryonic hemocyte cell differentiation" EXACT [] +is_a: GO:0042386 ! hemocyte differentiation +relationship: part_of GO:0035162 ! embryonic hemopoiesis + +[Term] +id: GO:0035164 +name: embryonic plasmatocyte differentiation +namespace: biological_process +def: "The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte." [GOC:bf, PMID:11921077, PMID:8174791] +synonym: "embryonic plasmatocyte cell differentiation" EXACT [] +is_a: GO:0035163 ! embryonic hemocyte differentiation +is_a: GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0035165 +name: embryonic crystal cell differentiation +namespace: biological_process +def: "The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm] +is_a: GO:0035163 ! embryonic hemocyte differentiation +is_a: GO:0042688 ! crystal cell differentiation + +[Term] +id: GO:0035166 +name: post-embryonic hemopoiesis +namespace: biological_process +def: "The stages of blood cell formation that take place after completion of embryonic development." [GOC:bf] +synonym: "post-embryonic haemopoiesis" EXACT [] +is_a: GO:0030097 ! hemopoiesis +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0009791 ! post-embryonic development + +[Term] +id: GO:0035167 +name: larval lymph gland hemopoiesis +namespace: biological_process +def: "The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages." [GOC:bf, GOC:mtg_sensu, PMID:12445385] +synonym: "larval lymph gland haematopoiesis" EXACT [] +synonym: "larval lymph gland haemopoiesis" EXACT [] +synonym: "larval lymph gland hematopoiesis" EXACT [] +is_a: GO:0035166 ! post-embryonic hemopoiesis +relationship: part_of GO:0002164 ! larval development +relationship: part_of GO:0048542 ! lymph gland development + +[Term] +id: GO:0035168 +name: larval lymph gland hemocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:14602069] +synonym: "larval lymph gland arthropod blood cell differentiation" EXACT [] +is_a: GO:0042386 ! hemocyte differentiation +relationship: part_of GO:0035167 ! larval lymph gland hemopoiesis + +[Term] +id: GO:0035169 +name: lymph gland plasmatocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte." [GOC:bf, PMID:11921077, PMID:8174791] +synonym: "lymph gland plasmatocyte cell differentiation" EXACT [] +is_a: GO:0035168 ! larval lymph gland hemocyte differentiation +is_a: GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0035170 +name: lymph gland crystal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm] +is_a: GO:0035168 ! larval lymph gland hemocyte differentiation +is_a: GO:0042688 ! crystal cell differentiation + +[Term] +id: GO:0035171 +name: lamellocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [GOC:bf, PMID:14734104] +synonym: "lamellocyte cell differentiation" EXACT [] +is_a: GO:0035168 ! larval lymph gland hemocyte differentiation +is_a: GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0035172 +name: hemocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] +synonym: "arthropod blood cell proliferation" EXACT [] +is_a: GO:0002376 ! immune system process +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0035173 +name: histone kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:bf] +is_a: GO:0004672 ! protein kinase activity +relationship: part_of GO:0016572 ! histone phosphorylation + +[Term] +id: GO:0035174 +name: histone serine kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:bf] +synonym: "histone-serine kinase activity" EXACT [] +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0035173 ! histone kinase activity +relationship: part_of GO:0035404 ! histone-serine phosphorylation + +[Term] +id: GO:0035175 +name: histone kinase activity (H3-S10 specific) +namespace: molecular_function +alt_id: GO:0044021 +def: "Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3." [GOC:bf, PMID:15041176] +synonym: "histone kinase activity (H3-S3 specific)" EXACT [] +synonym: "histone serine kinase activity (H3-S10 specific)" EXACT [] +synonym: "histone-serine kinase activity (H3-S10 specific)" EXACT [] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0043987 ! histone H3-S10 phosphorylation + +[Term] +id: GO:0035176 +name: social behavior +namespace: biological_process +def: "Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group." [GOC:jh2, PMID:12848939, Wikipedia:Social_behavior] +comment: Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior. +synonym: "cooperative behavior" RELATED [] +synonym: "social behaviour" EXACT [] +xref: Wikipedia:Social_behavior +is_a: GO:0007610 ! behavior +is_a: GO:0051703 ! intraspecies interaction between organisms + +[Term] +id: GO:0035177 +name: larval foraging behavior +namespace: biological_process +def: "The movement of a larva through a feeding substrate whilst feeding on food." [PMID:12848927] +synonym: "larval foraging behaviour" EXACT [] +is_a: GO:0030537 ! larval behavior +is_a: GO:0060756 ! foraging behavior + +[Term] +id: GO:0035178 +name: turning behavior +namespace: biological_process +def: "Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source." [PMID:10880478] +synonym: "turning behaviour" EXACT [] +is_a: GO:0007626 ! locomotory behavior + +[Term] +id: GO:0035179 +name: larval turning behavior +namespace: biological_process +def: "Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source." [PMID:10880478] +synonym: "larval turning behaviour" EXACT [] +is_a: GO:0008345 ! larval locomotory behavior +is_a: GO:0035178 ! turning behavior + +[Term] +id: GO:0035180 +name: larval wandering behavior +namespace: biological_process +def: "The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction." [PMID:12848927, PMID:12956960] +synonym: "larval wandering behaviour" EXACT [] +is_a: GO:0008345 ! larval locomotory behavior + +[Term] +id: GO:0035181 +name: larval burrowing behavior +namespace: biological_process +def: "Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation." [PMID:12848927, PMID:12848939] +synonym: "larval burrowing behaviour" EXACT [] +is_a: GO:0008345 ! larval locomotory behavior + +[Term] +id: GO:0035182 +name: female germline ring canal outer rim +namespace: cellular_component +def: "An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues." [PMID:12435357, PMID:7925006] +comment: See also the fly_anatomy.ontology term 'outer nurse cell ring canal rim ; FBbt:00004882'. +synonym: "germline ring canal outer rim" BROAD [] +synonym: "nurse cell ring canal outer rim" NARROW [] +synonym: "ovarian ring canal outer rim" NARROW [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0035324 ! female germline ring canal + +[Term] +id: GO:0035183 +name: female germline ring canal inner rim +namespace: cellular_component +def: "A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins." [PMID:10556087, PMID:7925006, PMID:9093858] +comment: See also the fly_anatomy.ontology term 'inner nurse cell ring canal rim ; FBbt:00004881'. +synonym: "germline ring canal inner rim" BROAD [] +synonym: "nurse cell ring canal inner rim" NARROW [] +synonym: "ovarian ring canal inner rim" NARROW [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0035324 ! female germline ring canal + +[Term] +id: GO:0035184 +name: histone threonine kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:bf] +synonym: "histone-threonine kinase activity" EXACT [] +is_a: GO:0004674 ! protein serine/threonine kinase activity +is_a: GO:0035173 ! histone kinase activity +relationship: part_of GO:0035405 ! histone-threonine phosphorylation + +[Term] +id: GO:0035185 +name: preblastoderm mitotic cell cycle +namespace: biological_process +def: "The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis." [ISBN:0879694238] +is_a: GO:0033301 ! cell cycle comprising mitosis without cytokinesis +is_a: GO:0045448 ! mitotic cell cycle, embryonic + +[Term] +id: GO:0035186 +name: syncytial blastoderm mitotic cell cycle +namespace: biological_process +def: "Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively." [ISBN:0879694238] +is_a: GO:0033301 ! cell cycle comprising mitosis without cytokinesis +is_a: GO:0045448 ! mitotic cell cycle, embryonic + +[Term] +id: GO:0035187 +name: hatching behavior +namespace: biological_process +def: "The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell." [GOC:pr, PMID:10436051] +synonym: "hatching behaviour" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0035188 ! hatching + +[Term] +id: GO:0035188 +name: hatching +namespace: biological_process +def: "The emergence of an immature organism from a protective structure." [GOC:dgh, GOC:isa_complete, ISBN:0198612001] +is_a: GO:0071684 ! organism emergence from protective structure +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0035189 +name: Rb-E2F complex +namespace: cellular_component +def: "A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression." [PMID:14616073] +synonym: "retinoblastoma-E2F complex" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0035190 +name: syncytial nuclear migration +namespace: biological_process +def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839] +is_a: GO:0007097 ! nuclear migration +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0035191 +name: nuclear axial expansion +namespace: biological_process +def: "The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex." [PMID:8314839] +synonym: "nuclear distribution along anterior-posterior axis" EXACT [] +synonym: "nucleus distribution along anterior-posterior axis" EXACT [] +is_a: GO:0035190 ! syncytial nuclear migration + +[Term] +id: GO:0035192 +name: nuclear cortical migration +namespace: biological_process +def: "The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo." [PMID:8314839] +is_a: GO:0035190 ! syncytial nuclear migration + +[Term] +id: GO:0035193 +name: larval central nervous system remodeling +namespace: biological_process +def: "Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster." [GOC:sensu, PMID:9647692] +synonym: "central nervous system metamorphosis" EXACT [] +synonym: "CNS metamorphosis" EXACT [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0002165 ! instar larval or pupal development +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0035194 +name: post-transcriptional gene silencing by RNA +namespace: biological_process +def: "Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation." [GOC:aruk, GOC:bc, GOC:mah, GOC:rl, PMID:15020054, PMID:15066275, PMID:15066283, PMID:23985560, PMID:28379604] +synonym: "posttranscriptional gene silencing by RNA" EXACT [] +synonym: "RNA-mediated posttranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] +synonym: "sense-PTGS" RELATED [] +is_a: GO:0016441 ! posttranscriptional gene silencing +is_a: GO:0031047 ! gene silencing by RNA + +[Term] +id: GO:0035195 +name: gene silencing by miRNA +namespace: biological_process +def: "Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA." [GOC:aruk, GOC:bc, GOC:rl, PMID:14744438, PMID:15066275, PMID:15066283, PMID:23209154, PMID:23985560, PMID:28379604] +synonym: "gene silencing by microRNA" EXACT [GOC:pr] +synonym: "microRNA-mediated gene silencing" EXACT [] +synonym: "miRNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb] +is_a: GO:0035194 ! post-transcriptional gene silencing by RNA + +[Term] +id: GO:0035196 +name: production of miRNAs involved in gene silencing by miRNA +namespace: biological_process +alt_id: GO:0030918 +def: "Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts." [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:15066275, PMID:15066283, PMID:23985560, PMID:28379604] +synonym: "gene silencing by miRNA, production of miRNAs" EXACT [GOC:mah] +synonym: "microRNA biogenesis" RELATED [GOC:tb] +synonym: "microRNA biosynthesis" RELATED [] +synonym: "microRNA biosynthetic process" RELATED [] +synonym: "microRNA metabolic process" RELATED [] +synonym: "microRNA metabolism" RELATED [] +synonym: "microRNA processing" BROAD [] +synonym: "microRNA-mediated gene silencing, production of microRNAs" EXACT [] +synonym: "miRNA biogenesis" RELATED [GOC:tb] +synonym: "miRNA processing" EXACT [] +synonym: "miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:dph, GOC:tb] +synonym: "production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:pr] +is_a: GO:0070918 ! production of small RNA involved in gene silencing by RNA +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0035197 +name: siRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme." [PMID:15066275, PMID:15066283] +synonym: "small interfering RNA binding" EXACT [] +is_a: GO:0061980 ! regulatory RNA binding + +[Term] +id: GO:0035198 +name: miRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes." [PMID:15066283] +synonym: "microRNA binding" EXACT [] +is_a: GO:0061980 ! regulatory RNA binding + +[Term] +id: GO:0035199 +name: salt aversion +namespace: biological_process +def: "The specific avoidance actions or reactions of an organism in response to the perception of salt." [GOC:bf] +synonym: "behavioral response to salt" BROAD [] +is_a: GO:0007631 ! feeding behavior +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0035200 +name: leg disc anterior/posterior pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc." [GOC:bf] +is_a: GO:0007448 ! anterior/posterior pattern specification, imaginal disc +is_a: GO:0035223 ! leg disc pattern formation + +[Term] +id: GO:0035201 +name: leg disc anterior/posterior lineage restriction +namespace: biological_process +def: "Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:bf] +is_a: GO:0048099 ! anterior/posterior lineage restriction, imaginal disc +relationship: part_of GO:0035200 ! leg disc anterior/posterior pattern formation + +[Term] +id: GO:0035202 +name: tracheal pit formation in open tracheal system +namespace: biological_process +def: "Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11063940, PMID:11992723, PMID:14570584] +synonym: "tracheal placode invagination" RELATED [] +synonym: "tracheal sac formation" BROAD [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035203 +name: regulation of lamellocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] +is_a: GO:0045613 ! regulation of plasmatocyte differentiation +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035171 ! lamellocyte differentiation +relationship: regulates GO:0035171 ! lamellocyte differentiation + +[Term] +id: GO:0035204 +name: negative regulation of lamellocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] +synonym: "down regulation of lamellocyte differentiation" EXACT [] +synonym: "down-regulation of lamellocyte differentiation" EXACT [] +synonym: "downregulation of lamellocyte differentiation" EXACT [] +synonym: "inhibition of lamellocyte differentiation" NARROW [] +is_a: GO:0035203 ! regulation of lamellocyte differentiation +is_a: GO:0045614 ! negative regulation of plasmatocyte differentiation +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:1903707 ! negative regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035171 ! lamellocyte differentiation +relationship: negatively_regulates GO:0035171 ! lamellocyte differentiation + +[Term] +id: GO:0035205 +name: positive regulation of lamellocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] +synonym: "activation of lamellocyte differentiation" NARROW [] +synonym: "stimulation of lamellocyte differentiation" NARROW [] +synonym: "up regulation of lamellocyte differentiation" EXACT [] +synonym: "up-regulation of lamellocyte differentiation" EXACT [] +synonym: "upregulation of lamellocyte differentiation" EXACT [] +is_a: GO:0035203 ! regulation of lamellocyte differentiation +is_a: GO:0045615 ! positive regulation of plasmatocyte differentiation +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:1903708 ! positive regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035171 ! lamellocyte differentiation +relationship: positively_regulates GO:0035171 ! lamellocyte differentiation + +[Term] +id: GO:0035206 +name: regulation of hemocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "regulation of arthropod blood cell proliferation" EXACT [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035172 ! hemocyte proliferation +relationship: regulates GO:0035172 ! hemocyte proliferation + +[Term] +id: GO:0035207 +name: negative regulation of hemocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "down regulation of hemocyte proliferation" EXACT [] +synonym: "down-regulation of hemocyte proliferation" EXACT [] +synonym: "downregulation of hemocyte proliferation" EXACT [] +synonym: "inhibition of hemocyte proliferation" NARROW [] +synonym: "negative regulation of arthropod blood cell proliferation" EXACT [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0035206 ! regulation of hemocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035172 ! hemocyte proliferation +relationship: negatively_regulates GO:0035172 ! hemocyte proliferation + +[Term] +id: GO:0035208 +name: positive regulation of hemocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "activation of hemocyte proliferation" NARROW [] +synonym: "positive regulation of arthropod blood cell proliferation" EXACT [] +synonym: "stimulation of hemocyte proliferation" NARROW [] +synonym: "up regulation of hemocyte proliferation" EXACT [] +synonym: "up-regulation of hemocyte proliferation" EXACT [] +synonym: "upregulation of hemocyte proliferation" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0035206 ! regulation of hemocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035172 ! hemocyte proliferation +relationship: positively_regulates GO:0035172 ! hemocyte proliferation + +[Term] +id: GO:0035209 +name: pupal development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0002165 ! instar larval or pupal development + +[Term] +id: GO:0035210 +name: prepupal development +namespace: biological_process +def: "The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation." [GOC:mtg_sensu, http://sdb.bio.purdue.edu/fly/aimain/1adult.htm] +comment: See also the fly_anatomy.ontology term 'prepupa ; FBbt:00002952'. +is_a: GO:0002165 ! instar larval or pupal development + +[Term] +id: GO:0035211 +name: spermathecum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk." [PMID:12679097] +comment: See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'. +is_a: GO:0009887 ! animal organ morphogenesis + +[Term] +id: GO:0035212 +name: cell competition in a multicellular organism +namespace: biological_process +def: "Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells." [GOC:bf, PMID:1116643, PMID:15066286] +is_a: GO:0009987 ! cellular process +is_a: GO:0040008 ! regulation of growth +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0035213 +name: clypeo-labral disc development +namespace: biological_process +def: "The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite." [GOC:bf, ISBN:0879694238] +synonym: "development of structures derived from the clypeo-labral disc" EXACT [] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035214 +name: eye-antennal disc development +namespace: biological_process +def: "Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035215 +name: genital disc development +namespace: biological_process +def: "Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia." [GOC:bf, ISBN:0879694238, PMID:11494318] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035216 +name: haltere disc development +namespace: biological_process +def: "Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035217 +name: labial disc development +namespace: biological_process +def: "Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035218 +name: leg disc development +namespace: biological_process +def: "Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035219 +name: prothoracic disc development +namespace: biological_process +def: "Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035220 +name: wing disc development +namespace: biological_process +def: "Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura." [GOC:bf, ISBN:0879694238] +is_a: GO:0007444 ! imaginal disc development + +[Term] +id: GO:0035221 +name: genital disc pattern formation +namespace: biological_process +def: "The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc." [GOC:bf] +is_a: GO:0007447 ! imaginal disc pattern formation +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0035222 +name: wing disc pattern formation +namespace: biological_process +def: "The process giving rise to the pattern of cell differentiation in the wing imaginal disc." [GOC:bf] +is_a: GO:0007447 ! imaginal disc pattern formation +relationship: part_of GO:0035220 ! wing disc development + +[Term] +id: GO:0035223 +name: leg disc pattern formation +namespace: biological_process +def: "The process that gives rise to the patterns of cell differentiation in the leg imaginal disc." [GOC:bf] +is_a: GO:0007447 ! imaginal disc pattern formation +relationship: part_of GO:0035218 ! leg disc development + +[Term] +id: GO:0035224 +name: genital disc anterior/posterior pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium)." [PMID:11494318] +is_a: GO:0007448 ! anterior/posterior pattern specification, imaginal disc +is_a: GO:0035221 ! genital disc pattern formation + +[Term] +id: GO:0035225 +name: determination of genital disc primordium +namespace: biological_process +def: "Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two." [GOC:bf, PMID:11494318] +is_a: GO:0007445 ! determination of imaginal disc primordium +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0035226 +name: glutamate-cysteine ligase catalytic subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase." [PMID:12954617] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0035227 +name: regulation of glutamate-cysteine ligase activity +namespace: biological_process +def: "Any process that modulates the activity of glutamate-cysteine ligase." [GOC:bf] +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004357 ! glutamate-cysteine ligase activity +relationship: regulates GO:0004357 ! glutamate-cysteine ligase activity + +[Term] +id: GO:0035228 +name: negative regulation of glutamate-cysteine ligase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase." [GOC:bf] +synonym: "down regulation of glutamate-cysteine ligase activity" EXACT [] +synonym: "down-regulation of glutamate-cysteine ligase activity" EXACT [] +synonym: "downregulation of glutamate-cysteine ligase activity" EXACT [] +synonym: "inhibition of glutamate-cysteine ligase activity" NARROW [] +is_a: GO:0035227 ! regulation of glutamate-cysteine ligase activity +is_a: GO:0051352 ! negative regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004357 ! glutamate-cysteine ligase activity +relationship: negatively_regulates GO:0004357 ! glutamate-cysteine ligase activity + +[Term] +id: GO:0035229 +name: positive regulation of glutamate-cysteine ligase activity +namespace: biological_process +def: "Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate." [PMID:12954617] +synonym: "activation of glutamate-cysteine ligase activity" NARROW [] +synonym: "stimulation of glutamate-cysteine ligase activity" NARROW [] +synonym: "up regulation of glutamate-cysteine ligase activity" EXACT [] +synonym: "up-regulation of glutamate-cysteine ligase activity" EXACT [] +synonym: "upregulation of glutamate-cysteine ligase activity" EXACT [] +is_a: GO:0035227 ! regulation of glutamate-cysteine ligase activity +is_a: GO:0051351 ! positive regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004357 ! glutamate-cysteine ligase activity +relationship: positively_regulates GO:0004357 ! glutamate-cysteine ligase activity + +[Term] +id: GO:0035230 +name: cytoneme +namespace: cellular_component +def: "A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um." [PMID:10367889, PMID:10675901] +subset: goslim_pir +synonym: "membrane nanotube" EXACT [Wikipedia:Membrane_nanotube] +xref: Wikipedia:Membrane_nanotube +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0035231 +name: cytoneme assembly +namespace: biological_process +def: "Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell." [PMID:10367889, PMID:10675901] +synonym: "cytoneme biogenesis" RELATED [GOC:mah] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: part_of GO:0003399 ! cytoneme morphogenesis + +[Term] +id: GO:0035232 +name: germ cell attraction +namespace: biological_process +def: "The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target." [PMID:12885551] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0050918 ! positive chemotaxis +is_a: GO:0060326 ! cell chemotaxis +relationship: part_of GO:0008354 ! germ cell migration + +[Term] +id: GO:0035233 +name: germ cell repulsion +namespace: biological_process +def: "The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue." [PMID:12885551] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0050919 ! negative chemotaxis +is_a: GO:0060326 ! cell chemotaxis +relationship: part_of GO:0008354 ! germ cell migration + +[Term] +id: GO:0035234 +name: ectopic germ cell programmed cell death +namespace: biological_process +def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944] +synonym: "programmed cell death of ectopic germ cells" EXACT [] +synonym: "programmed cell death, ectopic germ cells" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010623 ! programmed cell death involved in cell development + +[Term] +id: GO:0035235 +name: ionotropic glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:0198506732] +synonym: "ionotropic glutamate receptor signalling pathway" EXACT [] +is_a: GO:0007215 ! glutamate receptor signaling pathway + +[Term] +id: GO:0035236 +name: proctolin receptor activity +namespace: molecular_function +def: "Combining with the neuropeptide proctolin, to initiate a change in cell activity." [GOC:bf] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0035237 +name: corazonin receptor activity +namespace: molecular_function +def: "Combining with the neuropeptide corazonin to initiate a change in cell activity." [GOC:bf] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0035238 +name: vitamin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids." [PMID:11158606] +synonym: "vitamin A anabolism" EXACT [] +synonym: "vitamin A biosynthesis" EXACT [] +synonym: "vitamin A formation" EXACT [] +synonym: "vitamin A synthesis" EXACT [] +is_a: GO:0006776 ! vitamin A metabolic process +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0042362 ! fat-soluble vitamin biosynthetic process + +[Term] +id: GO:0035239 +name: tube morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0035295 ! tube development + +[Term] +id: GO:0035240 +name: dopamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." [ISBN:0198506732] +is_a: GO:0008144 ! drug binding +is_a: GO:0043169 ! cation binding +is_a: GO:1901338 ! catecholamine binding + +[Term] +id: GO:0035241 +name: protein-arginine omega-N monomethyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine." [EC:2.1.1.321, PMID:14705965, RESID:AA0069] +comment: Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further. +synonym: "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)" RELATED [EC:2.1.1.321] +synonym: "type III protein arginine methyltransferase activity" RELATED [EC:2.1.1.321] +xref: EC:2.1.1.321 +xref: RESID:AA0069 +xref: RHEA:48100 +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity +relationship: part_of GO:0035247 ! peptidyl-arginine omega-N-methylation + +[Term] +id: GO:0035242 +name: protein-arginine omega-N asymmetric methyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues." [PMID:14705965, RESID:AA0068, RESID:AA0069, RHEA:48096] +comment: Note that type I protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242'. +synonym: "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming)" RELATED [EC:2.1.1.319] +synonym: "type I PRMT activity" RELATED [] +synonym: "type I protein arginine methyltransferase activity" RELATED [2.1.1.319] +xref: EC:2.1.1.319 +xref: RESID:AA0068 +xref: RESID:AA0069 +xref: RHEA:48096 +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity +relationship: part_of GO:0019919 ! peptidyl-arginine methylation, to asymmetrical-dimethyl arginine + +[Term] +id: GO:0035243 +name: protein-arginine omega-N symmetric methyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues." [EC:2.1.1.320, PMID:14705965, RESID:AA0067, RESID:AA0069] +comment: Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'. +synonym: "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming)" RELATED [EC:2.1.1.320] +synonym: "type II PRMT activity" RELATED [] +synonym: "type II protein arginine methyltransferase activity" RELATED [] +xref: EC:2.1.1.320 +xref: Reactome:R-HSA-6804383 "PRMT5 methylates TP53" +xref: RESID:AA0067 +xref: RESID:AA0069 +xref: RHEA:48108 +is_a: GO:0016274 ! protein-arginine N-methyltransferase activity +relationship: part_of GO:0019918 ! peptidyl-arginine methylation, to symmetrical-dimethyl arginine + +[Term] +id: GO:0035244 +name: peptidyl-arginine C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein." [GOC:bf] +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0008276 ! protein methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +relationship: part_of GO:0035245 ! peptidyl-arginine C-methylation + +[Term] +id: GO:0035245 +name: peptidyl-arginine C-methylation +namespace: biological_process +def: "The addition of a methyl group onto a carbon atom of an arginine residue in a protein." [GOC:bf] +is_a: GO:0018216 ! peptidyl-arginine methylation + +[Term] +id: GO:0035246 +name: peptidyl-arginine N-methylation +namespace: biological_process +def: "The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein." [GOC:bf] +is_a: GO:0018216 ! peptidyl-arginine methylation + +[Term] +id: GO:0035247 +name: peptidyl-arginine omega-N-methylation +namespace: biological_process +def: "The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein." [PMID:14705965, RESID:AA0067, RESID:AA0068, RESID:AA0069] +xref: RESID:AA0067 +xref: RESID:AA0068 +xref: RESID:AA0069 +is_a: GO:0035246 ! peptidyl-arginine N-methylation + +[Term] +id: GO:0035248 +name: alpha-1,4-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage." [PMID:15130086] +synonym: "alpha-1,4-GalNAc transferase activity" EXACT [] +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0035249 +name: synaptic transmission, glutamatergic +namespace: biological_process +def: "The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos] +synonym: "glutamatergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0035250 +name: UDP-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule." [PMID:19858195] +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0035251 +name: UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule." [PMID:19858195] +xref: MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-1912353 "Glucosylation of Pre-NOTCH by POGLUT1" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0035252 +name: UDP-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule." [PMID:30127001] +xref: Reactome:R-HSA-5617138 "B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA" +xref: Reactome:R-HSA-6785668 "Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA" +xref: Reactome:R-HSA-9638090 "B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0042285 ! xylosyltransferase activity + +[Term] +id: GO:0035253 +name: ciliary rootlet +namespace: cellular_component +def: "A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm." [GOC:cilia, PMID:12427867] +synonym: "cilial rootlet" EXACT [] +synonym: "cilium rootlet" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0005929 ! cilium + +[Term] +id: GO:0035254 +name: glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a glutamate receptor." [GOC:bf] +subset: goslim_chembl +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0035255 +name: ionotropic glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels." [GOC:bf, ISBN:0198506732] +is_a: GO:0035254 ! glutamate receptor binding + +[Term] +id: GO:0035256 +name: G protein-coupled glutamate receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a G protein-coupled glutamate receptor (a metabotropic glutamate receptor)." [GOC:bf, ISBN:0198506732, PMID:9069287] +synonym: "G-protein coupled glutamate receptor binding" EXACT [] +synonym: "metabotropic glutamate receptor binding" EXACT [GOC:bf] +is_a: GO:0001664 ! G protein-coupled receptor binding +is_a: GO:0035254 ! glutamate receptor binding + +[Term] +id: GO:0035257 +name: nuclear hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell." [GOC:bf] +is_a: GO:0051427 ! hormone receptor binding +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding + +[Term] +id: GO:0035258 +name: steroid hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a steroid hormone receptor." [GOC:bf] +is_a: GO:0035257 ! nuclear hormone receptor binding + +[Term] +id: GO:0035259 +name: glucocorticoid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a glucocorticoid receptor." [GOC:bf] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0035258 ! steroid hormone receptor binding + +[Term] +id: GO:0035260 +name: internal genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html] +is_a: GO:0035112 ! genitalia morphogenesis + +[Term] +id: GO:0035261 +name: external genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html] +is_a: GO:0035112 ! genitalia morphogenesis + +[Term] +id: GO:0035262 +name: gonad morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0008406 ! gonad development + +[Term] +id: GO:0035263 +name: genital disc sexually dimorphic development +namespace: biological_process +def: "The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed." [PMID:11290302, PMID:11494318, PMID:11702781] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007548 ! sex differentiation +relationship: part_of GO:0035215 ! genital disc development + +[Term] +id: GO:0035264 +name: multicellular organism growth +namespace: biological_process +def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb] +synonym: "body growth" RELATED [] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0048589 ! developmental growth + +[Term] +id: GO:0035265 +name: organ growth +namespace: biological_process +def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0048589 ! developmental growth + +[Term] +id: GO:0035266 +name: meristem growth +namespace: biological_process +def: "The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation." [GOC:bf, ISBN:0198547684] +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0048507 ! meristem development + +[Term] +id: GO:0035267 +name: NuA4 histone acetyltransferase complex +namespace: cellular_component +def: "A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60)." [GOC:ecd, PMID:10966108, PMID:14966270] +synonym: "TIP60 histone acetylase complex" EXACT [] +synonym: "TIP60 histone acetyltransferase complex" EXACT [] +is_a: GO:0043189 ! H4/H2A histone acetyltransferase complex + +[Term] +id: GO:0035268 +name: protein mannosylation +namespace: biological_process +def: "The addition of a mannose residue to a protein acceptor molecule." [GOC:bf, GOC:pr] +synonym: "protein amino acid mannosylation" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation +is_a: GO:0097502 ! mannosylation + +[Term] +id: GO:0035269 +name: protein O-linked mannosylation +namespace: biological_process +def: "The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage." [GOC:bf, PMID:9878797] +synonym: "protein amino acid O-linked mannosylation" EXACT [GOC:bf] +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0035268 ! protein mannosylation + +[Term] +id: GO:0035270 +name: endocrine system development +namespace: biological_process +def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0035271 +name: ring gland development +namespace: biological_process +def: "Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones." [GOC:bf, PMID:11223816, PMID:9584098] +comment: See also the fly_anatomy.ontology terms 'ring gland ; FBbt:00001722, 'prothoracic gland ; FBbt:00001724', 'corpus allatum ; FBbt:00005800' and 'corpus cardiacum ; FBbt:00005799. +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0035272 +name: exocrine system development +namespace: biological_process +def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0035273 +name: phthalate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phthalate, any ester or salt of phthalic acid." [http://umbbd.ahc.umn.edu/pth/pth_map.html] +subset: goslim_pir +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding + +[Term] +id: GO:0035274 +name: diphenyl phthalate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with diphenyl phthalate, C(20)H(14)O(4)." [http://www.sigmaaldrich.com] +synonym: "DPP binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding + +[Term] +id: GO:0035275 +name: dibutyl phthalate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dibutyl phthalate, C(16)H(22)O(4)." [http://www.sigmaaldrich.com] +synonym: "DBP binding" EXACT [] +synonym: "phthalic acid dibutyl ester binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding + +[Term] +id: GO:0035276 +name: ethanol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH." [ISBN:0198506732] +is_a: GO:0008144 ! drug binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0035277 +name: spiracle morphogenesis, open tracheal system +namespace: biological_process +def: "The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk." [GOC:mtg_sensu, PMID:10491268] +synonym: "spiracle morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0035278 +name: miRNA mediated inhibition of translation +namespace: biological_process +def: "The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs." [PMID:14744438, PMID:15196554] +synonym: "down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:mah] +synonym: "down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:mah] +synonym: "downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:mah] +synonym: "gene silencing by miRNA, negative regulation of translation" EXACT [GOC:mah] +synonym: "inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:mah] +synonym: "miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:pr] +is_a: GO:0040033 ! negative regulation of translation, ncRNA-mediated +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0035279 +name: mRNA cleavage involved in gene silencing by miRNA +namespace: biological_process +def: "The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism." [GOC:dph, GOC:mtg_lung, PMID:14744438, PMID:15196554] +synonym: "gene silencing by miRNA, mRNA cleavage" EXACT [GOC:mah] +synonym: "miRNA-mediated gene silencing, mRNA cleavage" EXACT [GOC:dph, GOC:tb] +synonym: "mRNA cleavage involved in gene silencing by microRNA" EXACT [GOC:pr] +is_a: GO:0098795 ! mRNA cleavage involved in gene silencing +intersection_of: GO:0006379 ! mRNA cleavage +intersection_of: part_of GO:0035195 ! gene silencing by miRNA +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0035280 +name: miRNA loading onto RISC involved in gene silencing by miRNA +namespace: biological_process +def: "The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC)." [PMID:14744438] +synonym: "gene silencing by miRNA, miRNA loading onto RISC" EXACT [GOC:mah] +synonym: "microRNA loading onto RISC involved in gene silencing by microRNA" EXACT [GOC:pr] +synonym: "miRISC assembly" BROAD [] +synonym: "miRNA-mediated gene silencing, miRNA loading onto RISC" EXACT [GOC:dph, GOC:tb] +is_a: GO:0070922 ! small RNA loading onto RISC +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0035281 +name: pre-miRNA export from nucleus +namespace: biological_process +def: "Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product." [GOC:sl, PMID:14744438] +synonym: "pre-microRNA export from cell nucleus" EXACT [] +synonym: "pre-microRNA export from nucleus" RELATED [] +synonym: "pre-microRNA export out of nucleus" EXACT [] +synonym: "pre-microRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "pre-microRNA-nucleus export" EXACT [] +is_a: GO:0006405 ! RNA export from nucleus +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0035282 +name: segmentation +namespace: biological_process +def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689] +xref: Wikipedia:Segmentation_(biology) +is_a: GO:0003002 ! regionalization + +[Term] +id: GO:0035283 +name: central nervous system segmentation +namespace: biological_process +def: "Division of the central nervous system into a series of semi-repetitive parts or segments." [GOC:bf] +is_a: GO:0035282 ! segmentation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0035284 +name: brain segmentation +namespace: biological_process +def: "Division of the brain into a series of semi-repetitive parts or segments." [GOC:bf] +is_a: GO:0035282 ! segmentation +relationship: part_of GO:0007420 ! brain development +relationship: part_of GO:0035283 ! central nervous system segmentation + +[Term] +id: GO:0035285 +name: appendage segmentation +namespace: biological_process +def: "Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented." [PMID:10357895] +is_a: GO:0035282 ! segmentation +relationship: part_of GO:0035107 ! appendage morphogenesis + +[Term] +id: GO:0035286 +name: obsolete leg segmentation +namespace: biological_process +def: "OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint." [PMID:10357895] +comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. +synonym: "leg segmentation" EXACT [] +is_obsolete: true +consider: GO:0035285 +consider: GO:0036011 + +[Term] +id: GO:0035287 +name: head segmentation +namespace: biological_process +def: "Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial)." [PMID:10477305, PMID:7915837] +comment: See also the fly_anatomy.ontology term 'head segment ; FBbt:00000006' and its children. +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0007350 ! blastoderm segmentation +relationship: part_of GO:0060322 ! head development +property_value: RO:0002161 NCBITaxon:7742 + +[Term] +id: GO:0035288 +name: anterior head segmentation +namespace: biological_process +def: "Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments." [PMID:15382136] +comment: See also the fly_anatomy.ontology term 'procephalic segment ; FBbt:00000007' and its children. +synonym: "procephalic segmentation" RELATED [] +is_a: GO:0035287 ! head segmentation +relationship: part_of GO:0097065 ! anterior head development + +[Term] +id: GO:0035289 +name: posterior head segmentation +namespace: biological_process +def: "Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains." [PMID:15382136] +comment: See also the fly_anatomy.ontology term 'gnathal segment ; FBbt:00000011' and its children. +synonym: "gnathal segmentation" RELATED [] +is_a: GO:0035287 ! head segmentation + +[Term] +id: GO:0035290 +name: trunk segmentation +namespace: biological_process +def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402] +is_a: GO:0035282 ! segmentation +relationship: part_of GO:0007350 ! blastoderm segmentation + +[Term] +id: GO:0035291 +name: specification of segmental identity, intercalary segment +namespace: biological_process +def: "The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437, PMID:10477305] +comment: See also the fly_anatomy.ontology term 'intercalary segment ; FBbt:00000010'. +is_a: GO:0007380 ! specification of segmental identity, head +relationship: part_of GO:0035288 ! anterior head segmentation + +[Term] +id: GO:0035292 +name: specification of segmental identity, trunk +namespace: biological_process +def: "The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [PMID:1360402] +is_a: GO:0007379 ! segment specification +relationship: part_of GO:0035290 ! trunk segmentation + +[Term] +id: GO:0035293 +name: chitin-based larval cuticle pattern formation +namespace: biological_process +def: "The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +is_a: GO:0035017 ! cuticle pattern formation +relationship: part_of GO:0008363 ! larval chitin-based cuticle development + +[Term] +id: GO:0035294 +name: determination of wing disc primordium +namespace: biological_process +def: "Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc." [ISBN:0879694238] +is_a: GO:0007445 ! determination of imaginal disc primordium +is_a: GO:0035220 ! wing disc development + +[Term] +id: GO:0035295 +name: tube development +namespace: biological_process +def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0035296 +name: regulation of tube diameter +namespace: biological_process +def: "Any process that modulates the diameter of a tube." [GOC:bf] +is_a: GO:0035150 ! regulation of tube size + +[Term] +id: GO:0035297 +name: regulation of Malpighian tubule diameter +namespace: biological_process +def: "Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells." [PMID:9286684] +is_a: GO:0035296 ! regulation of tube diameter +is_a: GO:0035298 ! regulation of Malpighian tubule size + +[Term] +id: GO:0035298 +name: regulation of Malpighian tubule size +namespace: biological_process +def: "Ensuring that a Malpighian tubule is the correct length and diameter." [GOC:bf] +is_a: GO:0035150 ! regulation of tube size +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis + +[Term] +id: GO:0035299 +name: inositol pentakisphosphate 2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+)." [EC:2.7.1.158, RHEA:20313] +synonym: "ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.158] +synonym: "Gsl1p" RELATED [EC:2.7.1.158] +synonym: "inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity" EXACT [EC:2.7.1.158] +synonym: "inositol polyphosphate kinase activity" EXACT [EC:2.7.1.158] +synonym: "inositol-pentakisphosphate 2-kinase activity" EXACT [EC:2.7.1.158] +synonym: "Ins(1,3,4,5,6)P5 2-kinase activity" EXACT [EC:2.7.1.158] +synonym: "IP5 2-kinase activity" EXACT [EC:2.7.1.158] +synonym: "Ipk1p" RELATED [EC:2.7.1.158] +xref: EC:2.7.1.158 +xref: KEGG_REACTION:R05202 +xref: MetaCyc:RXN-7163 +xref: Reactome:R-HSA-1855176 "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus" +xref: Reactome:R-HSA-1855179 "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol" +xref: RHEA:20313 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0035300 +name: obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate." [EC:2.7.1.159, PMID:9126335] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.159] +synonym: "inositol 1,3,4-trisphosphate 5-kinase activity" NARROW [] +synonym: "inositol 1,3,4-trisphosphate 6-kinase activity" NARROW [] +synonym: "inositol trisphosphate 5/6-kinase activity" EXACT [EC:2.7.1.159] +synonym: "inositol-1,3,4-trisphosphate 5/6-kinase activity" EXACT [] +synonym: "Ins(1,3,4)P3 5/6-kinase activity" EXACT [EC:2.7.1.159] +synonym: "IP56K" RELATED [EC:2.7.1.159] +is_obsolete: true +consider: GO:0052725 +consider: GO:0052726 + +[Term] +id: GO:0035301 +name: Hedgehog signaling complex +namespace: cellular_component +def: "A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila)." [PMID:10825151, PMID:15057936] +synonym: "Hedgehog signalling complex" EXACT [] +synonym: "HSC" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0035302 +name: ecdysteroid 25-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods." [ISBN:0198506732, PMID:15350618] +comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol). +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0035303 +name: regulation of dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016311 ! dephosphorylation +relationship: regulates GO:0016311 ! dephosphorylation + +[Term] +id: GO:0035304 +name: regulation of protein dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] +synonym: "regulation of protein amino acid dephosphorylation" EXACT [GOC:bf] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:0035303 ! regulation of dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006470 ! protein dephosphorylation +relationship: regulates GO:0006470 ! protein dephosphorylation + +[Term] +id: GO:0035305 +name: negative regulation of dephosphorylation +namespace: biological_process +def: "Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] +synonym: "down regulation of dephosphorylation" EXACT [] +synonym: "down-regulation of dephosphorylation" EXACT [] +synonym: "downregulation of dephosphorylation" EXACT [] +synonym: "inhibition of dephosphorylation" NARROW [] +is_a: GO:0035303 ! regulation of dephosphorylation +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016311 ! dephosphorylation +relationship: negatively_regulates GO:0016311 ! dephosphorylation + +[Term] +id: GO:0035306 +name: positive regulation of dephosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] +synonym: "activation of dephosphorylation" NARROW [] +synonym: "stimulation of dephosphorylation" NARROW [] +synonym: "up regulation of dephosphorylation" EXACT [] +synonym: "up-regulation of dephosphorylation" EXACT [] +synonym: "upregulation of dephosphorylation" EXACT [] +is_a: GO:0035303 ! regulation of dephosphorylation +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016311 ! dephosphorylation +relationship: positively_regulates GO:0016311 ! dephosphorylation + +[Term] +id: GO:0035307 +name: positive regulation of protein dephosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] +synonym: "activation of protein amino acid dephosphorylation" NARROW [] +synonym: "positive regulation of protein amino acid dephosphorylation" EXACT [GOC:bf] +synonym: "stimulation of protein amino acid dephosphorylation" NARROW [] +synonym: "up regulation of protein amino acid dephosphorylation" EXACT [] +synonym: "up-regulation of protein amino acid dephosphorylation" EXACT [] +synonym: "upregulation of protein amino acid dephosphorylation" EXACT [] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:0035304 ! regulation of protein dephosphorylation +is_a: GO:0035306 ! positive regulation of dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006470 ! protein dephosphorylation +relationship: positively_regulates GO:0006470 ! protein dephosphorylation + +[Term] +id: GO:0035308 +name: negative regulation of protein dephosphorylation +namespace: biological_process +def: "Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] +synonym: "down regulation of protein amino acid dephosphorylation" EXACT [] +synonym: "down-regulation of protein amino acid dephosphorylation" EXACT [] +synonym: "downregulation of protein amino acid dephosphorylation" EXACT [] +synonym: "inhibition of protein amino acid dephosphorylation" NARROW [] +synonym: "negative regulation of protein amino acid dephosphorylation" EXACT [GOC:bf] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0035304 ! regulation of protein dephosphorylation +is_a: GO:0035305 ! negative regulation of dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006470 ! protein dephosphorylation +relationship: negatively_regulates GO:0006470 ! protein dephosphorylation + +[Term] +id: GO:0035309 +name: wing and notum subfield formation +namespace: biological_process +def: "The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures." [PMID:10860999] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0035220 ! wing disc development + +[Term] +id: GO:0035310 +name: notum cell fate specification +namespace: biological_process +def: "The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment." [PMID:10860999] +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0035309 ! wing and notum subfield formation + +[Term] +id: GO:0035311 +name: wing cell fate specification +namespace: biological_process +def: "The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment." [PMID:10860999] +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0035309 ! wing and notum subfield formation + +[Term] +id: GO:0035312 +name: 5'-3' exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule." [ISBN:0198547684] +is_a: GO:0008409 ! 5'-3' exonuclease activity +is_a: GO:0016895 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0035313 +name: wound healing, spreading of epidermal cells +namespace: biological_process +def: "The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis." [GOC:bf, PMID:15269788] +is_a: GO:0044319 ! wound healing, spreading of cells + +[Term] +id: GO:0035314 +name: scab formation +namespace: biological_process +def: "Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection." [GOC:bf, PMID:15269788] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0035315 +name: hair cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a hair cell." [GOC:bf] +is_a: GO:0009913 ! epidermal cell differentiation +is_a: GO:0030182 ! neuron differentiation + +[Term] +id: GO:0035316 +name: non-sensory hair organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis." [GOC:mtg_sensu, PMID:11064425] +comment: See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'. +synonym: "non-sensory hair organization and biogenesis" RELATED [GOC:mah] +synonym: "trichome organisation" BROAD [] +synonym: "trichome organization and biogenesis" BROAD [] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +relationship: part_of GO:0035315 ! hair cell differentiation + +[Term] +id: GO:0035317 +name: imaginal disc-derived wing hair organization +namespace: biological_process +def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11064425, PMID:12540853] +comment: See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'. +synonym: "imaginal disc-derived wing hair organization and biogenesis" RELATED [GOC:mah] +synonym: "wing hair organisation" EXACT [] +synonym: "wing hair organization and biogenesis" RELATED [GOC:mah] +synonym: "wing trichome organization and biogenesis" EXACT [] +is_a: GO:0035316 ! non-sensory hair organization +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis + +[Term] +id: GO:0035318 +name: imaginal disc-derived wing hair outgrowth +namespace: biological_process +def: "Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair." [GOC:mtg_sensu, PMID:11064425, PMID:8947551] +synonym: "wing hair outgrowth" EXACT [] +synonym: "wing prehair outgrowth" RELATED [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0048858 ! cell projection morphogenesis +relationship: part_of GO:0035317 ! imaginal disc-derived wing hair organization + +[Term] +id: GO:0035319 +name: imaginal disc-derived wing hair elongation +namespace: biological_process +def: "Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles." [GOC:mtg_sensu, PMID:11832234] +synonym: "wing hair elongation" EXACT [] +synonym: "wing prehair extension" RELATED [] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0048858 ! cell projection morphogenesis +relationship: part_of GO:0035317 ! imaginal disc-derived wing hair organization + +[Term] +id: GO:0035320 +name: imaginal disc-derived wing hair site selection +namespace: biological_process +def: "Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally." [GOC:mtg_transport, ISBN:0815340729, PMID:8947551] +synonym: "prehair localization" RELATED [] +synonym: "wing hair site selection" EXACT [] +is_a: GO:0022606 ! establishment of proximal/distal cell polarity +relationship: part_of GO:0001737 ! establishment of imaginal disc-derived wing hair orientation + +[Term] +id: GO:0035321 +name: maintenance of imaginal disc-derived wing hair orientation +namespace: biological_process +def: "Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity." [GOC:mtg_sensu, PMID:15501220] +synonym: "maintenance of wing hair orientation" EXACT [] +is_a: GO:0009954 ! proximal/distal pattern formation +relationship: part_of GO:0035317 ! imaginal disc-derived wing hair organization + +[Term] +id: GO:0035322 +name: mesenchymal cell migration involved in limb bud formation +namespace: biological_process +def: "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh] +is_a: GO:0090497 ! mesenchymal cell migration +intersection_of: GO:0090497 ! mesenchymal cell migration +intersection_of: part_of GO:0060174 ! limb bud formation +relationship: part_of GO:0090496 ! mesenchyme migration involved in limb bud formation +created_by: bf +creation_date: 2010-02-24T02:05:14Z + +[Term] +id: GO:0035323 +name: male germline ring canal +namespace: cellular_component +def: "An intercellular bridge that connects the germline cells of a male cyst." [PMID:9635420] +synonym: "spermatocyte ring canal" NARROW [] +synonym: "testicular ring canal" NARROW [] +is_a: GO:0045172 ! germline ring canal +created_by: bf +creation_date: 2010-02-25T11:05:14Z + +[Term] +id: GO:0035324 +name: female germline ring canal +namespace: cellular_component +def: "An intercellular bridge that connects the germline cells of a female cyst." [PMID:9635420] +synonym: "nurse cell ring canal" NARROW [] +synonym: "ovarian ring canal" NARROW [] +is_a: GO:0045172 ! germline ring canal +created_by: bf +creation_date: 2010-02-25T11:06:41Z + +[Term] +id: GO:0035325 +name: Toll-like receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response." [PMID:19076341] +synonym: "TLR binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2010-02-26T10:11:55Z + +[Term] +id: GO:0035327 +name: transcriptionally active chromatin +namespace: cellular_component +def: "The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed." [GOC:sart, PMID:17965872] +is_a: GO:0000785 ! chromatin +created_by: bf +creation_date: 2010-02-26T10:23:02Z + +[Term] +id: GO:0035328 +name: transcriptionally silent chromatin +namespace: cellular_component +def: "The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed." [GOC:sart, PMID:17965872] +synonym: "transcriptionally inactive chromatin" EXACT [] +is_a: GO:0000785 ! chromatin +created_by: bf +creation_date: 2010-02-26T10:24:13Z + +[Term] +id: GO:0035329 +name: hippo signaling +namespace: biological_process +def: "The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1." [PMID:17318211, PMID:18328423] +synonym: "hippo signal transduction" EXACT [GOC:signaling] +synonym: "hippo signaling cascade" RELATED [GOC:signaling] +synonym: "hippo signaling pathway" EXACT [] +synonym: "hippo signalling cascade" RELATED [GOC:mah] +synonym: "Salvador-Warts-Hippo signaling pathway" NARROW [] +synonym: "SWH pathway" NARROW [] +is_a: GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2010-02-26T10:43:33Z + +[Term] +id: GO:0035330 +name: regulation of hippo signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hippo signaling." [GOC:bf] +synonym: "regulation of hippo signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of hippo signaling pathway" EXACT [] +synonym: "regulation of hippo signalling cascade" RELATED [GOC:mah] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035329 ! hippo signaling +relationship: regulates GO:0035329 ! hippo signaling +created_by: bf +creation_date: 2010-02-26T10:53:05Z + +[Term] +id: GO:0035331 +name: negative regulation of hippo signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling." [GOC:bf] +synonym: "negative regulation of hippo signaling cascade" RELATED [GOC:signaling] +synonym: "negative regulation of hippo signaling pathway" EXACT [] +synonym: "negative regulation of hippo signalling cascade" RELATED [GOC:mah] +is_a: GO:0035330 ! regulation of hippo signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035329 ! hippo signaling +relationship: negatively_regulates GO:0035329 ! hippo signaling +created_by: bf +creation_date: 2010-02-26T10:54:19Z + +[Term] +id: GO:0035332 +name: positive regulation of hippo signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hippo signaling." [GOC:bf] +synonym: "positive regulation of hippo signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of hippo signaling pathway" EXACT [] +synonym: "positive regulation of hippo signalling cascade" RELATED [GOC:mah] +is_a: GO:0035330 ! regulation of hippo signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035329 ! hippo signaling +relationship: positively_regulates GO:0035329 ! hippo signaling +created_by: bf +creation_date: 2010-02-26T10:54:59Z + +[Term] +id: GO:0035333 +name: Notch receptor processing, ligand-dependent +namespace: biological_process +def: "The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD)." [GOC:bf, PMID:12651094] +synonym: "Notch S2 cleavage" NARROW [PMID:12651094] +synonym: "Notch S3 cleavage" NARROW [PMID:12651094] +is_a: GO:0031293 ! membrane protein intracellular domain proteolysis +relationship: part_of GO:0007219 ! Notch signaling pathway +relationship: part_of GO:0007220 ! Notch receptor processing +created_by: bf +creation_date: 2010-02-26T02:31:31Z + +[Term] +id: GO:0035334 +name: Notch receptor processing, ligand-independent +namespace: biological_process +def: "The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface." [GOC:bf, PMID:12651094] +synonym: "Notch S1 cleavage" NARROW [PMID:12651094] +is_a: GO:0016485 ! protein processing +relationship: part_of GO:0007220 ! Notch receptor processing +created_by: bf +creation_date: 2010-02-26T02:32:46Z + +[Term] +id: GO:0035335 +name: peptidyl-tyrosine dephosphorylation +namespace: biological_process +def: "The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine." [GOC:bf] +is_a: GO:0006470 ! protein dephosphorylation +created_by: bf +creation_date: 2010-03-01T01:09:14Z + +[Term] +id: GO:0035336 +name: long-chain fatty-acyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more." [ISBN:0198506732] +synonym: "long-chain fatty acyl CoA metabolic process" EXACT [] +synonym: "long-chain fatty acyl-CoA metabolism" EXACT [] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: bf +creation_date: 2010-03-02T11:01:43Z + +[Term] +id: GO:0035337 +name: fatty-acyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group." [ISBN:0198506732] +synonym: "fatty acyl CoA metabolic process" EXACT [] +synonym: "fatty-acyl-CoA metabolism" EXACT [] +is_a: GO:0006637 ! acyl-CoA metabolic process +is_a: GO:1901568 ! fatty acid derivative metabolic process +created_by: bf +creation_date: 2010-03-02T11:05:48Z + +[Term] +id: GO:0035338 +name: long-chain fatty-acyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more." [ISBN:0198506732] +synonym: "long-chain fatty acyl CoA biosynthetic process" EXACT [] +synonym: "long-chain fatty-acyl-CoA anabolism" EXACT [] +synonym: "long-chain fatty-acyl-CoA biosynthesis" EXACT [] +synonym: "long-chain fatty-acyl-CoA formation" EXACT [] +synonym: "long-chain fatty-acyl-CoA synthesis" EXACT [] +is_a: GO:0035336 ! long-chain fatty-acyl-CoA metabolic process +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +created_by: bf +creation_date: 2010-03-02T11:07:15Z + +[Term] +id: GO:0035339 +name: SPOTS complex +namespace: cellular_component +def: "A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis." [PMID:20182505] +synonym: "serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex" NARROW [] +is_a: GO:0017059 ! serine C-palmitoyltransferase complex +created_by: bf +creation_date: 2010-03-03T10:28:42Z + +[Term] +id: GO:0035340 +name: inosine transport +namespace: biological_process +def: "The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [PMID:19135251] +synonym: "hypoxanthine riboside transport" EXACT [] +is_a: GO:0015858 ! nucleoside transport +created_by: bf +creation_date: 2010-03-04T10:00:58Z + +[Term] +id: GO:0035341 +name: regulation of inosine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "regulation of hypoxanthine riboside transport" EXACT [] +is_a: GO:0032245 ! regulation of purine nucleoside transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035340 ! inosine transport +relationship: regulates GO:0035340 ! inosine transport +created_by: bf +creation_date: 2010-03-04T10:03:51Z + +[Term] +id: GO:0035342 +name: positive regulation of inosine transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "positive regulation of hypoxanthine riboside transport" EXACT [] +is_a: GO:0032248 ! positive regulation of purine nucleoside transport +is_a: GO:0035341 ! regulation of inosine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035340 ! inosine transport +relationship: positively_regulates GO:0035340 ! inosine transport +created_by: bf +creation_date: 2010-03-04T10:05:03Z + +[Term] +id: GO:0035343 +name: negative regulation of inosine transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "negative regulation of hypoxanthine riboside transport" EXACT [] +is_a: GO:0032247 ! negative regulation of purine nucleoside transport +is_a: GO:0035341 ! regulation of inosine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035340 ! inosine transport +relationship: negatively_regulates GO:0035340 ! inosine transport +created_by: bf +creation_date: 2010-03-04T10:06:07Z + +[Term] +id: GO:0035344 +name: hypoxanthine transport +namespace: biological_process +def: "The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:sl] +synonym: "6-hydroxypurine transport" EXACT [] +synonym: "hypoxanthine transmembrane transport" EXACT [GOC:mah] +is_a: GO:0006863 ! purine nucleobase transport +created_by: bf +creation_date: 2010-03-04T10:39:55Z + +[Term] +id: GO:0035345 +name: regulation of hypoxanthine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "regulation of 6-hydroxypurine transport" EXACT [] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035344 ! hypoxanthine transport +relationship: regulates GO:0035344 ! hypoxanthine transport +created_by: bf +creation_date: 2010-03-04T10:42:04Z + +[Term] +id: GO:0035346 +name: positive regulation of hypoxanthine transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "positive regulation of 6-hydroxypurine transport" EXACT [] +is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport +is_a: GO:0035345 ! regulation of hypoxanthine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035344 ! hypoxanthine transport +relationship: positively_regulates GO:0035344 ! hypoxanthine transport +created_by: bf +creation_date: 2010-03-04T10:42:48Z + +[Term] +id: GO:0035347 +name: negative regulation of hypoxanthine transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf] +synonym: "negative regulation of 6-hydroxypurine transport" EXACT [] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0035345 ! regulation of hypoxanthine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035344 ! hypoxanthine transport +relationship: negatively_regulates GO:0035344 ! hypoxanthine transport +created_by: bf +creation_date: 2010-03-04T10:43:53Z + +[Term] +id: GO:0035348 +name: acetyl-CoA transmembrane transport +namespace: biological_process +def: "The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GO:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "acetyl-CoA membrane transport" EXACT [] +is_a: GO:0015876 ! acetyl-CoA transport +is_a: GO:0071106 ! adenosine 3',5'-bisphosphate transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:42:23Z + +[Term] +id: GO:0035349 +name: coenzyme A transmembrane transport +namespace: biological_process +def: "The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "coenzyme A membrane transport" EXACT [] +is_a: GO:0015880 ! coenzyme A transport +is_a: GO:0071106 ! adenosine 3',5'-bisphosphate transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:44:33Z + +[Term] +id: GO:0035350 +name: FAD transmembrane transport +namespace: biological_process +def: "The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form." [GOC:bf, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "FAD membrane transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:45:11Z + +[Term] +id: GO:0035351 +name: heme transmembrane transport +namespace: biological_process +def: "The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "heme membrane transport" EXACT [] +is_a: GO:0015886 ! heme transport +is_a: GO:0034755 ! iron ion transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:45:46Z + +[Term] +id: GO:0035352 +name: NAD transmembrane transport +namespace: biological_process +def: "The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "NAD membrane transport" EXACT [] +is_a: GO:0043132 ! NAD transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:46:20Z + +[Term] +id: GO:0035353 +name: nicotinamide mononucleotide transmembrane transport +namespace: biological_process +def: "The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP." [GOC:bf, ISBN:0721662544] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "nicotinamide mononucleotide membrane transport" EXACT [] +is_a: GO:0015890 ! nicotinamide mononucleotide transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: bf +creation_date: 2010-03-04T03:46:55Z + +[Term] +id: GO:0035354 +name: Toll-like receptor 1-Toll-like receptor 2 protein complex +namespace: cellular_component +alt_id: GO:0038125 +def: "A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2)." [GOC:add, GOC:signaling, PMID:17889651, PMID:21481769] +synonym: "TLR1-TLR2 protein complex" EXACT [] +synonym: "TLR1:TLR2 complex" EXACT [] +synonym: "TLR2:TLR1 heterodimer" EXACT [GOC:bf] +synonym: "toll-like receptor TLR1:TLR2 heterodimeric complex" EXACT [GOC:bf] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2010-03-04T04:35:44Z + +[Term] +id: GO:0035355 +name: Toll-like receptor 2-Toll-like receptor 6 protein complex +namespace: cellular_component +alt_id: GO:0038126 +def: "A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6)." [GOC:add, GOC:signaling, PMID:19931471, PMID:21481769] +synonym: "TLR2-TLR6 protein complex" EXACT [] +synonym: "TLR2:TLR6 heterodimer" EXACT [GOC:bf] +synonym: "TLR6:TLR2 complex" EXACT [] +synonym: "toll-like receptor TLR6:TLR2 heterodimeric complex" EXACT [GOC:bf] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2010-03-04T04:37:00Z + +[Term] +id: GO:0035356 +name: cellular triglyceride homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment." [GOC:BHF] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:0070328 ! triglyceride homeostasis +created_by: bf +creation_date: 2010-03-05T10:28:11Z + +[Term] +id: GO:0035357 +name: peroxisome proliferator activated receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes." [GOC:BHF, PMID:18221086] +synonym: "peroxisome proliferator activated receptor signalling pathway" EXACT [GOC:mah] +synonym: "peroxisome proliferator-activated receptor signaling pathway" EXACT [] +synonym: "PPAR signaling pathway" EXACT [] +is_a: GO:0030522 ! intracellular receptor signaling pathway +created_by: bf +creation_date: 2010-03-05T10:30:10Z + +[Term] +id: GO:0035358 +name: regulation of peroxisome proliferator activated receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf] +synonym: "regulation of peroxisome proliferator activated receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of peroxisome proliferator-activated receptor signaling pathway" EXACT [] +synonym: "regulation of PPAR signaling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +relationship: regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +created_by: bf +creation_date: 2010-03-05T10:39:37Z + +[Term] +id: GO:0035359 +name: negative regulation of peroxisome proliferator activated receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf] +synonym: "negative regulation of peroxisome proliferator activated receptor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of peroxisome proliferator-activated receptor signaling pathway" EXACT [] +synonym: "negative regulation of PPAR signaling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0035358 ! regulation of peroxisome proliferator activated receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +relationship: negatively_regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +created_by: bf +creation_date: 2010-03-05T10:41:35Z + +[Term] +id: GO:0035360 +name: positive regulation of peroxisome proliferator activated receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway." [GOC:bf] +synonym: "positive regulation of peroxisome proliferator activated receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of peroxisome proliferator-activated receptor signaling pathway" EXACT [] +synonym: "positive regulation of PPAR signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0035358 ! regulation of peroxisome proliferator activated receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +relationship: positively_regulates GO:0035357 ! peroxisome proliferator activated receptor signaling pathway +created_by: bf +creation_date: 2010-03-05T10:43:10Z + +[Term] +id: GO:0035361 +name: Cul8-RING ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins." [GOC:krc, PMID:20139071] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex +created_by: bf +creation_date: 2010-03-05T02:41:12Z + +[Term] +id: GO:0035362 +name: protein-DNA ISRE complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA." [GOC:amm, PMID:11747630] +synonym: "protein-DNA interferon-stimulated response element complex assembly" EXACT [] +is_a: GO:0065004 ! protein-DNA complex assembly +created_by: bf +creation_date: 2010-03-10T10:40:09Z + +[Term] +id: GO:0035363 +name: histone locus body +namespace: cellular_component +def: "A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body." [GOC:sart, PMID:16533947, PMID:18927579, PMID:19620235] +synonym: "HLB" EXACT [PMID:16533947, PMID:18927579, PMID:19620235] +is_a: GO:0016604 ! nuclear body +created_by: bf +creation_date: 2010-03-10T10:44:01Z + +[Term] +id: GO:0035364 +name: thymine transport +namespace: biological_process +def: "The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO:sl] +synonym: "5-methyluracil transport" EXACT [] +synonym: "thymine transmembrane transport" EXACT [GOC:mah] +is_a: GO:0015855 ! pyrimidine nucleobase transport +created_by: bf +creation_date: 2010-03-11T10:20:24Z + +[Term] +id: GO:0035365 +name: regulation of thymine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl] +synonym: "regulation of 5-methyluracil transport" EXACT [] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035364 ! thymine transport +relationship: regulates GO:0035364 ! thymine transport +created_by: bf +creation_date: 2010-03-11T10:22:54Z + +[Term] +id: GO:0035366 +name: negative regulation of thymine transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl] +synonym: "negative regulation of 5-methyluracil transport" EXACT [] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0035365 ! regulation of thymine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035364 ! thymine transport +relationship: negatively_regulates GO:0035364 ! thymine transport +created_by: bf +creation_date: 2010-03-11T10:23:42Z + +[Term] +id: GO:0035367 +name: positive regulation of thymine transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:sl] +synonym: "positive regulation of 5-methyluracil transport" EXACT [] +is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport +is_a: GO:0035365 ! regulation of thymine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035364 ! thymine transport +relationship: positively_regulates GO:0035364 ! thymine transport +created_by: bf +creation_date: 2010-03-11T10:24:25Z + +[Term] +id: GO:0035368 +name: selenocysteine insertion sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation." [GOC:imk, PMID:10760958] +synonym: "SECIS binding" EXACT [] +is_a: GO:0003729 ! mRNA binding +created_by: bf +creation_date: 2010-03-11T10:42:28Z + +[Term] +id: GO:0035369 +name: pre-B cell receptor complex +namespace: cellular_component +def: "An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:16464608, PMID:17306522] +comment: Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome. +synonym: "pre-BCR" EXACT [] +is_a: GO:0098796 ! membrane protein complex +created_by: bf +creation_date: 2010-03-11T10:46:10Z + +[Term] +id: GO:0035370 +name: UBC13-UEV1A complex +namespace: cellular_component +def: "A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A)." [GOC:amm, PMID:16129784] +is_a: GO:0031371 ! ubiquitin conjugating enzyme complex +created_by: bf +creation_date: 2010-03-11T10:53:09Z + +[Term] +id: GO:0035371 +name: microtubule plus-end +namespace: cellular_component +def: "The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability." [GOC:bf, GOC:lb, PMID:12700769, PMID:16643273] +synonym: "growing microtubule plus end" EXACT [] +synonym: "microtubule plus end" EXACT [] +is_a: GO:1990752 ! microtubule end +created_by: bf +creation_date: 2010-03-11T10:55:00Z + +[Term] +id: GO:0035372 +name: protein localization to microtubule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb] +synonym: "protein localisation to microtubule" EXACT [GOC:mah] +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +created_by: bf +creation_date: 2010-03-11T11:00:56Z + +[Term] +id: GO:0035373 +name: chondroitin sulfate proteoglycan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit." [GOC:kmv, ISBN:0198506732] +is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043394 ! proteoglycan binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bf +creation_date: 2010-03-12T10:23:55Z + +[Term] +id: GO:0035374 +name: chondroitin sulfate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc)." [GOC:kmv, ISBN:0198506732] +is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bf +creation_date: 2010-03-12T10:25:34Z + +[Term] +id: GO:0035375 +name: zymogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis." [ISBN:0198506732] +synonym: "proenzyme binding" NARROW [ISBN:0198506732] +is_a: GO:0019899 ! enzyme binding +created_by: bf +creation_date: 2010-03-18T10:50:35Z + +[Term] +id: GO:0035376 +name: sterol import +namespace: biological_process +def: "The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:bf, PMID:19793923] +synonym: "sterol influx" EXACT [PMID:12077145] +synonym: "sterol uptake" EXACT [PMID:12077145] +is_a: GO:0015918 ! sterol transport +created_by: bf +creation_date: 2010-03-18T10:53:01Z + +[Term] +id: GO:0035377 +name: transepithelial water transport +namespace: biological_process +def: "The directed movement of water (H2O) from one side of an epithelium to the other." [GOC:yaf] +is_a: GO:0006833 ! water transport +is_a: GO:0042045 ! epithelial fluid transport +created_by: bf +creation_date: 2010-03-18T10:55:38Z + +[Term] +id: GO:0035378 +name: carbon dioxide transmembrane transport +namespace: biological_process +def: "The process in which carbon dioxide (CO2) is transported across a membrane." [GOC:yaf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "carbon dioxide membrane transport" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015670 ! carbon dioxide transport +created_by: bf +creation_date: 2010-03-18T11:17:54Z + +[Term] +id: GO:0035379 +name: carbon dioxide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other." [GOC:yaf] +xref: Reactome:R-HSA-1237042 "AQP1 passively tranlocates carbon dioxide from the extracellular region to the cytosol" +xref: Reactome:R-HSA-1237069 "RhAG passively translocates carbon dioxide from the extracellular region to the cytosol" +xref: Reactome:R-HSA-1247645 "RhAG passively translocates carbon dioxide from the cytosol to the extracellular region" +xref: Reactome:R-HSA-1247649 "AQP1 passively translocates carbon dioxide from the cytosol to the extracellular region" +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0035378 ! carbon dioxide transmembrane transport +created_by: bf +creation_date: 2010-03-18T11:19:38Z + +[Term] +id: GO:0035380 +name: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [GOC:pde] +synonym: "very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity" EXACT [] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2010-03-18T11:23:05Z + +[Term] +id: GO:0035381 +name: ATP-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts." [GOC:bf] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0022834 ! ligand-gated channel activity +created_by: bf +creation_date: 2010-03-18T01:21:45Z + +[Term] +id: GO:0035382 +name: sterol transmembrane transport +namespace: biological_process +def: "The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "sterol membrane transport" EXACT [] +is_a: GO:0015918 ! sterol transport +is_a: GO:0055085 ! transmembrane transport +created_by: bf +creation_date: 2010-03-18T01:24:39Z + +[Term] +id: GO:0035383 +name: thioester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol." [GOC:bf, Wikipedia:Thioester] +synonym: "thioester metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: bf +creation_date: 2010-03-18T01:48:12Z + +[Term] +id: GO:0035384 +name: thioester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol." [GOC:bf, http://encyclopedia.thefreedictionary.com/Thioester] +synonym: "thioester anabolism" EXACT [] +synonym: "thioester biosynthesis" EXACT [] +synonym: "thioester formation" EXACT [] +synonym: "thioester synthesis" EXACT [] +is_a: GO:0035383 ! thioester metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: bf +creation_date: 2010-03-18T01:52:11Z + +[Term] +id: GO:0035385 +name: Roundabout signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling] +synonym: "ROBO signaling pathway" EXACT [] +synonym: "ROBO/SLIT signaling pathway" EXACT [] +synonym: "Roundabout signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2010-03-18T02:38:31Z + +[Term] +id: GO:0035386 +name: regulation of Roundabout signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF] +synonym: "regulation of Roundabout signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035385 ! Roundabout signaling pathway +relationship: regulates GO:0035385 ! Roundabout signaling pathway +created_by: bf +creation_date: 2010-03-18T02:39:24Z + +[Term] +id: GO:0035387 +name: negative regulation of Roundabout signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF] +synonym: "negative regulation of Roundabout signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0035386 ! regulation of Roundabout signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035385 ! Roundabout signaling pathway +relationship: negatively_regulates GO:0035385 ! Roundabout signaling pathway +created_by: bf +creation_date: 2010-03-18T02:40:00Z + +[Term] +id: GO:0035388 +name: positive regulation of Roundabout signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway." [GOC:BHF] +synonym: "positive regulation of Roundabout signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0035386 ! regulation of Roundabout signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035385 ! Roundabout signaling pathway +relationship: positively_regulates GO:0035385 ! Roundabout signaling pathway +created_by: bf +creation_date: 2010-03-18T02:41:16Z + +[Term] +id: GO:0035391 +name: obsolete maintenance of chromatin silencing at silent mating-type cassette +namespace: biological_process +def: "OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci." [GOC:vw] +comment: This term was obsoleted because it represents a phenotype. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19301 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-03-22T10:25:14Z + +[Term] +id: GO:0035392 +name: obsolete maintenance of chromatin silencing at telomere +namespace: biological_process +def: "OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere." [GOC:vw] +comment: This term was obsoleted because it represented a phenotype. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19301 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-03-22T10:25:57Z + +[Term] +id: GO:0035393 +name: chemokine (C-X-C motif) ligand 9 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add] +synonym: "CXCL9 production" EXACT [] +synonym: "MIG production" EXACT [] +synonym: "Monokine induced by gamma interferon production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: bf +creation_date: 2010-03-23T10:03:20Z + +[Term] +id: GO:0035394 +name: regulation of chemokine (C-X-C motif) ligand 9 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf] +synonym: "regulation of CXCL9 production" EXACT [] +synonym: "regulation of MIG production" EXACT [] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +relationship: regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +created_by: bf +creation_date: 2010-03-23T10:06:19Z + +[Term] +id: GO:0035395 +name: negative regulation of chemokine (C-X-C motif) ligand 9 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf] +synonym: "negative regulation of CXCL9 production" EXACT [] +synonym: "negative regulation of MIG production" EXACT [] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0035394 ! regulation of chemokine (C-X-C motif) ligand 9 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +relationship: negatively_regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +created_by: bf +creation_date: 2010-03-23T10:06:44Z + +[Term] +id: GO:0035396 +name: positive regulation of chemokine (C-X-C motif) ligand 9 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9." [GOC:bf] +synonym: "positive regulation of CXCL9 production" EXACT [] +synonym: "positive regulation of MIG production" EXACT [] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0035394 ! regulation of chemokine (C-X-C motif) ligand 9 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +relationship: positively_regulates GO:0035393 ! chemokine (C-X-C motif) ligand 9 production +created_by: bf +creation_date: 2010-03-23T10:07:17Z + +[Term] +id: GO:0035397 +name: helper T cell enhancement of adaptive immune response +namespace: biological_process +def: "Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell." [GOC:add] +synonym: "provision of T cell help" EXACT [] +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +created_by: bf +creation_date: 2010-03-23T10:38:31Z + +[Term] +id: GO:0035398 +name: helper T cell enhancement of T cell mediated immune response +namespace: biological_process +def: "Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell." [GOC:add] +synonym: "helper T cell enhancement of T cell mediated immunity" EXACT [] +synonym: "provision of T cell help to T cell" EXACT [] +is_a: GO:0002711 ! positive regulation of T cell mediated immunity +is_a: GO:0035397 ! helper T cell enhancement of adaptive immune response +created_by: bf +creation_date: 2010-03-23T10:40:00Z + +[Term] +id: GO:0035399 +name: helper T cell enhancement of B cell mediated immune response +namespace: biological_process +def: "Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell." [GOC:add] +synonym: "helper T cell enhancement of B cell mediated immunity" EXACT [] +synonym: "provision of T cell help to B cell" EXACT [] +is_a: GO:0002714 ! positive regulation of B cell mediated immunity +is_a: GO:0035397 ! helper T cell enhancement of adaptive immune response +created_by: bf +creation_date: 2010-03-23T10:41:46Z + +[Term] +id: GO:0035400 +name: histone tyrosine kinase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:bf] +synonym: "histone-tyrosine kinase activity" EXACT [] +is_a: GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +is_a: GO:0035173 ! histone kinase activity +relationship: part_of GO:0035406 ! histone-tyrosine phosphorylation +created_by: bf +creation_date: 2010-03-24T09:59:15Z + +[Term] +id: GO:0035401 +name: histone kinase activity (H3-Y41 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3." [GOC:bf] +synonym: "histone tyrosine kinase activity (H3-Y41 specific)" EXACT [] +synonym: "histone-tyrosine kinase activity (H3-Y41 specific)" EXACT [] +is_a: GO:0035400 ! histone tyrosine kinase activity +relationship: part_of GO:0035409 ! histone H3-Y41 phosphorylation +created_by: bf +creation_date: 2010-03-24T10:01:14Z + +[Term] +id: GO:0035402 +name: histone kinase activity (H3-T11 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3." [GOC:bf] +synonym: "histone threonine kinase activity (H3-T11 specific)" EXACT [] +synonym: "histone-threonine kinase activity (H3-T11 specific)" EXACT [] +is_a: GO:0035184 ! histone threonine kinase activity +relationship: part_of GO:0035407 ! histone H3-T11 phosphorylation +created_by: bf +creation_date: 2010-03-24T10:04:40Z + +[Term] +id: GO:0035403 +name: histone kinase activity (H3-T6 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3." [GOC:bf] +synonym: "histone threonine kinase activity (H3-T6 specific)" EXACT [] +synonym: "histone-threonine kinase activity (H3-T6 specific)" EXACT [] +is_a: GO:0035184 ! histone threonine kinase activity +relationship: part_of GO:0035408 ! histone H3-T6 phosphorylation +created_by: bf +creation_date: 2010-03-24T10:05:39Z + +[Term] +id: GO:0035404 +name: histone-serine phosphorylation +namespace: biological_process +def: "The modification of histones by addition of a phosphate group to a serine residue." [GOC:bf] +synonym: "histone serine phosphorylation" EXACT [] +is_a: GO:0016572 ! histone phosphorylation +is_a: GO:0018105 ! peptidyl-serine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:08:25Z + +[Term] +id: GO:0035405 +name: histone-threonine phosphorylation +namespace: biological_process +def: "The modification of histones by addition of a phosphate group to a threonine residue." [GOC:bf] +synonym: "histone threonine phosphorylation" EXACT [] +is_a: GO:0016572 ! histone phosphorylation +is_a: GO:0018107 ! peptidyl-threonine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:09:21Z + +[Term] +id: GO:0035406 +name: histone-tyrosine phosphorylation +namespace: biological_process +def: "The modification of histones by addition of a phosphate group to a tyrosine residue." [GOC:bf] +synonym: "histone tyrosine phosphorylation" EXACT [] +is_a: GO:0016572 ! histone phosphorylation +is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:10:16Z + +[Term] +id: GO:0035407 +name: histone H3-T11 phosphorylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone." [GOC:bf] +is_a: GO:0035405 ! histone-threonine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:12:01Z + +[Term] +id: GO:0035408 +name: histone H3-T6 phosphorylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone." [GOC:bf] +is_a: GO:0035405 ! histone-threonine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:12:51Z + +[Term] +id: GO:0035409 +name: histone H3-Y41 phosphorylation +namespace: biological_process +def: "The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone." [GOC:bf] +is_a: GO:0035406 ! histone-tyrosine phosphorylation +created_by: bf +creation_date: 2010-03-24T10:13:13Z + +[Term] +id: GO:0035410 +name: dihydrotestosterone 17-beta-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH." [GOC:ecd, http://www.brenda-enzymes.org/php/result_flat.php4?ecno=1.1.1.63, PMID:4152755] +xref: EC:1.1.1.51 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2010-03-24T10:48:41Z + +[Term] +id: GO:0035415 +name: obsolete regulation of mitotic prometaphase +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "regulation of mitotic prometaphase" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T10:52:08Z + +[Term] +id: GO:0035416 +name: obsolete positive regulation of mitotic prometaphase +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "positive regulation of mitotic prometaphase" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T10:52:55Z + +[Term] +id: GO:0035417 +name: obsolete negative regulation of mitotic prometaphase +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region." [GOC:bf] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "negative regulation of mitotic prometaphase" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T10:53:42Z + +[Term] +id: GO:0035418 +name: protein localization to synapse +namespace: biological_process +def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf] +synonym: "protein localisation to synapse" EXACT [GOC:mah] +is_a: GO:1902414 ! protein localization to cell junction +created_by: bf +creation_date: 2010-03-29T10:58:53Z + +[Term] +id: GO:0035419 +name: obsolete activation of MAPK activity involved in innate immune response +namespace: biological_process +def: "OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +comment: This term was obsoleted because it should be represented as a GO-CAM model. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18000 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T01:25:24Z + +[Term] +id: GO:0035420 +name: MAPK cascade involved in innate immune response +namespace: biological_process +def: "A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +synonym: "MAPKKK cascade involved in innate immune response" EXACT [GOC:signaling] +is_a: GO:0000165 ! MAPK cascade +intersection_of: GO:0000165 ! MAPK cascade +intersection_of: part_of GO:0045087 ! innate immune response +relationship: part_of GO:0045087 ! innate immune response +created_by: bf +creation_date: 2010-03-29T01:25:59Z + +[Term] +id: GO:0035421 +name: obsolete activation of MAPKK activity involved in innate immune response +namespace: biological_process +def: "OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18000 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T01:26:44Z + +[Term] +id: GO:0035422 +name: obsolete activation of MAPKKK activity involved in innate immune response +namespace: biological_process +def: "OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +comment: This term was obsoleted because it should be represented as a GO-CAM model. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18000 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-03-29T01:27:38Z + +[Term] +id: GO:0035423 +name: inactivation of MAPK activity involved in innate immune response +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +is_a: GO:0000188 ! inactivation of MAPK activity +is_a: GO:0002766 ! innate immune response-inhibiting signal transduction +created_by: bf +creation_date: 2010-03-29T01:28:59Z + +[Term] +id: GO:0035424 +name: obsolete MAPK import into nucleus involved in innate immune response +namespace: biological_process +def: "OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:bf] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "nuclear translocation of MAPK involved in innate immune response" NARROW [GOC:mah] +is_obsolete: true +consider: GO:0006606 +created_by: bf +creation_date: 2010-03-29T01:29:36Z + +[Term] +id: GO:0035425 +name: autocrine signaling +namespace: biological_process +def: "Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type." [GOC:bf, ISBN:3527303782] +synonym: "autocrine signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +created_by: bf +creation_date: 2010-03-29T02:15:52Z + +[Term] +id: GO:0035426 +name: extracellular matrix-cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information between the extracellular matrix and a cell." [GOC:bf] +synonym: "cell-extracellular matrix signalling" EXACT [] +synonym: "extracellular matrix-cell signalling" EXACT [] +is_a: GO:0007154 ! cell communication +is_a: GO:0023052 ! signaling +created_by: bf +creation_date: 2010-03-29T02:26:54Z + +[Term] +id: GO:0035429 +name: gluconate transmembrane transport +namespace: biological_process +alt_id: GO:0015725 +def: "The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose." [GOC:vw, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "gluconate membrane transport" EXACT [] +synonym: "gluconate transport" RELATED [] +is_a: GO:0042873 ! aldonate transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:33:46Z + +[Term] +id: GO:0035430 +name: regulation of gluconate transmembrane transport +namespace: biological_process +alt_id: GO:0032893 +def: "Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw] +synonym: "regulation of gluconate membrane transport" EXACT [] +synonym: "regulation of gluconate transport" RELATED [] +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035429 ! gluconate transmembrane transport +relationship: regulates GO:0035429 ! gluconate transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:37:18Z + +[Term] +id: GO:0035431 +name: negative regulation of gluconate transmembrane transport +namespace: biological_process +alt_id: GO:0032894 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw] +synonym: "down regulation of gluconate transport" EXACT [] +synonym: "down-regulation of gluconate transport" EXACT [] +synonym: "downregulation of gluconate transport" EXACT [] +synonym: "inhibition of gluconate transport" NARROW [] +synonym: "negative regulation of gluconate membrane transport" EXACT [] +synonym: "negative regulation of gluconate transport" RELATED [] +is_a: GO:0032891 ! negative regulation of organic acid transport +is_a: GO:0035430 ! regulation of gluconate transmembrane transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035429 ! gluconate transmembrane transport +relationship: negatively_regulates GO:0035429 ! gluconate transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:39:08Z + +[Term] +id: GO:0035432 +name: positive regulation of gluconate transmembrane transport +namespace: biological_process +alt_id: GO:0032895 +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore." [GOC:vw] +synonym: "activation of gluconate transport" NARROW [] +synonym: "induction of gluconate transport" NARROW [] +synonym: "positive regulation of gluconate membrane transport" EXACT [] +synonym: "positive regulation of gluconate transport" RELATED [] +synonym: "stimulation of gluconate transport" NARROW [] +synonym: "up regulation of gluconate transport" EXACT [] +synonym: "up-regulation of gluconate transport" EXACT [] +synonym: "upregulation of gluconate transport" EXACT [] +is_a: GO:0032892 ! positive regulation of organic acid transport +is_a: GO:0035430 ! regulation of gluconate transmembrane transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035429 ! gluconate transmembrane transport +relationship: positively_regulates GO:0035429 ! gluconate transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:39:58Z + +[Term] +id: GO:0035433 +name: acetate transmembrane transport +namespace: biological_process +def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "acetate membrane transport" EXACT [] +is_a: GO:0006846 ! acetate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: bf +creation_date: 2010-04-08T10:59:01Z + +[Term] +id: GO:0035434 +name: copper ion transmembrane transport +namespace: biological_process +alt_id: GO:1901473 +def: "The directed movement of copper cation across a membrane." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "copper cation transmembrane transport" EXACT [] +synonym: "copper ion membrane transport" EXACT [] +is_a: GO:0006825 ! copper ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: bf +creation_date: 2010-04-08T11:03:23Z + +[Term] +id: GO:0035435 +name: phosphate ion transmembrane transport +namespace: biological_process +def: "The process in which a phosphate is transported across a membrane." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "phosphate ion membrane transport" EXACT [] +is_a: GO:0006817 ! phosphate ion transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: bf +creation_date: 2010-04-08T11:24:06Z + +[Term] +id: GO:0035436 +name: triose phosphate transmembrane transport +namespace: biological_process +def: "The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester." [GOC:bf, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "triose phosphate membrane transport" EXACT [] +synonym: "triose phosphate transmembrane transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015717 ! triose phosphate transport +is_a: GO:0098656 ! anion transmembrane transport +created_by: bf +creation_date: 2010-04-08T02:54:07Z + +[Term] +id: GO:0035437 +name: maintenance of protein localization in endoplasmic reticulum +namespace: biological_process +def: "Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum." [GOC:bf, GOC:vw] +synonym: "maintenance of protein localisation in endoplasmic reticulum" EXACT [GOC:mah] +synonym: "maintenance of protein localization in ER" EXACT [] +synonym: "maintenance of protein location in endoplasmic reticulum" EXACT [] +synonym: "maintenance of protein location in ER" EXACT [] +synonym: "protein-endoplasmic reticulum retention" EXACT [] +synonym: "protein-ER retention" EXACT [] +synonym: "retention of protein in endoplasmic reticulum" EXACT [] +synonym: "retention of protein in ER" EXACT [] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005783 ! endoplasmic reticulum +relationship: occurs_in GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0070972 ! protein localization to endoplasmic reticulum +created_by: bf +creation_date: 2010-04-09T10:39:49Z + +[Term] +id: GO:0035438 +name: cyclic-di-GMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate." [GOC:bf] +synonym: "3',5'-cyclic di-GMP binding" EXACT [] +synonym: "c-di-GMP binding" EXACT [] +synonym: "cyclic dinucleotide di-GMP binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0030551 ! cyclic nucleotide binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +created_by: bf +creation_date: 2010-04-09T02:40:17Z + +[Term] +id: GO:0035439 +name: halimadienyl-diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate." [EC:5.5.1.16] +synonym: "halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)" EXACT [EC:5.5.1.16] +synonym: "halimadienyl diphosphate synthase activity" EXACT [EC:5.5.1.16] +xref: EC:5.5.1.16 +xref: RHEA:25621 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016872 ! intramolecular lyase activity +created_by: bf +creation_date: 2010-04-09T02:59:35Z + +[Term] +id: GO:0035440 +name: tuberculosinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria." [MetaCyc:PWY-5935] +synonym: "halima-5,6,dien-15-ol biosynthesis" EXACT [] +synonym: "halima-5,6,dien-15-ol biosynthetic process" EXACT [] +synonym: "tuberculosinol biosynthesis" EXACT [] +xref: MetaCyc:PWY-5935 +is_a: GO:0016102 ! diterpenoid biosynthetic process +created_by: bf +creation_date: 2010-04-09T03:36:19Z + +[Term] +id: GO:0035441 +name: cell migration involved in vasculogenesis +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh] +is_a: GO:0016477 ! cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0001570 ! vasculogenesis +relationship: part_of GO:0001570 ! vasculogenesis +created_by: bf +creation_date: 2010-04-09T03:53:01Z + +[Term] +id: GO:0035442 +name: dipeptide transmembrane transport +namespace: biological_process +def: "The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "dipeptide membrane transport" EXACT [] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0042938 ! dipeptide transport +created_by: bf +creation_date: 2010-04-13T09:18:33Z + +[Term] +id: GO:0035443 +name: tripeptide transmembrane transport +namespace: biological_process +def: "The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "tripeptide membrane transport" EXACT [] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0042939 ! tripeptide transport +created_by: bf +creation_date: 2010-04-13T09:20:25Z + +[Term] +id: GO:0035444 +name: nickel cation transmembrane transport +namespace: biological_process +def: "The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "nickel cation membrane transport" EXACT [] +is_a: GO:0015675 ! nickel cation transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: bf +creation_date: 2010-04-13T09:22:51Z + +[Term] +id: GO:0035445 +name: borate transmembrane transport +namespace: biological_process +def: "The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals." [GOC:curators] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "borate membrane transport" EXACT [] +synonym: "boron transmembrane transport" RELATED [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0046713 ! borate transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: bf +creation_date: 2010-04-13T09:24:23Z + +[Term] +id: GO:0035446 +name: cysteine-glucosaminylinositol ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins." [EC:6.3.1.13, MetaCyc:RXN1G-4, PMID:12033919] +synonym: "desacetylmycothiol synthase" RELATED [PMID:12033919] +synonym: "L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase" EXACT [EC:6.3.1.13] +synonym: "MshC ligase" EXACT [EC:6.3.1.13] +xref: EC:6.3.1.13 +xref: MetaCyc:RXN1G-4 +xref: RHEA:26176 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity +created_by: bf +creation_date: 2010-04-14T11:33:06Z + +[Term] +id: GO:0035447 +name: mycothiol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol." [MetaCyc:MONOMER-9684, PMID:12033919] +synonym: "acetyl-CoA:Cys-GlcN-Ins acetyltransferase" EXACT [] +xref: MetaCyc:MONOMER-9684 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: bf +creation_date: 2010-04-14T11:40:26Z + +[Term] +id: GO:0035448 +name: extrinsic component of thylakoid membrane +namespace: cellular_component +def: "The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to thylakoid membrane" NARROW [] +synonym: "peripheral to thylakoid membrane" EXACT [] +is_a: GO:0019898 ! extrinsic component of membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0042651 ! thylakoid membrane +relationship: part_of GO:0042651 ! thylakoid membrane +created_by: bf +creation_date: 2010-04-16T10:11:32Z + +[Term] +id: GO:0035449 +name: extrinsic component of plastid thylakoid membrane +namespace: cellular_component +def: "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to plastid thylakoid membrane" NARROW [] +synonym: "peripheral to plastid thylakoid membrane" EXACT [] +is_a: GO:0035448 ! extrinsic component of thylakoid membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0055035 ! plastid thylakoid membrane +relationship: part_of GO:0055035 ! plastid thylakoid membrane +created_by: bf +creation_date: 2010-04-16T10:14:24Z + +[Term] +id: GO:0035450 +name: extrinsic component of lumenal side of plastid thylakoid membrane +namespace: cellular_component +def: "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to lumenal leaflet of plastid thylakoid membrane" EXACT [GOC:ab] +synonym: "extrinsic to lumenal side of plastid thylakoid membrane" NARROW [] +synonym: "peripheral to lumenal side of plastid thylakoid membrane" EXACT [] +is_a: GO:0035449 ! extrinsic component of plastid thylakoid membrane +is_a: GO:0035453 ! extrinsic component of plastid inner membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098570 ! stromal side of plastid inner membrane +relationship: part_of GO:0098570 ! stromal side of plastid inner membrane +created_by: bf +creation_date: 2010-04-16T10:17:25Z + +[Term] +id: GO:0035451 +name: extrinsic component of stromal side of plastid thylakoid membrane +namespace: cellular_component +def: "The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to stromal leaflet of plastid thylakoid membrane" EXACT [GOC:ab] +synonym: "extrinsic to stromal side of plastid thylakoid membrane" NARROW [] +synonym: "peripheral to stromal side of plastid thylakoid membrane" EXACT [] +is_a: GO:0035449 ! extrinsic component of plastid thylakoid membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098572 ! stromal side of plastid thylakoid membrane +relationship: part_of GO:0098572 ! stromal side of plastid thylakoid membrane +created_by: bf +creation_date: 2010-04-16T10:18:01Z + +[Term] +id: GO:0035452 +name: extrinsic component of plastid membrane +namespace: cellular_component +def: "The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to plastid membrane" NARROW [] +synonym: "peripheral to plastid membrane" EXACT [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0042170 ! plastid membrane +relationship: part_of GO:0042170 ! plastid membrane +created_by: bf +creation_date: 2010-04-16T10:19:33Z + +[Term] +id: GO:0035453 +name: extrinsic component of plastid inner membrane +namespace: cellular_component +def: "The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to plastid inner membrane" NARROW [] +synonym: "peripheral to plastid inner membrane" EXACT [] +is_a: GO:0035452 ! extrinsic component of plastid membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0009528 ! plastid inner membrane +relationship: part_of GO:0009528 ! plastid inner membrane +created_by: bf +creation_date: 2010-04-16T10:21:14Z + +[Term] +id: GO:0035454 +name: extrinsic component of stromal side of plastid inner membrane +namespace: cellular_component +def: "The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region." [GOC:bf, GOC:dos] +synonym: "extrinsic to stromal leaflet of plastid inner membrane" EXACT [GOC:ab] +synonym: "extrinsic to stromal side of plastid inner membrane" NARROW [] +synonym: "peripheral to stromal side of plastid inner membrane" EXACT [] +is_a: GO:0035450 ! extrinsic component of lumenal side of plastid thylakoid membrane +created_by: bf +creation_date: 2010-04-16T10:23:12Z + +[Term] +id: GO:0035455 +name: response to interferon-alpha +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon." [GOC:sl, PMID:11356686] +synonym: "response to interferon alfa-n1" RELATED [GOC:sl] +synonym: "response to interferon alfa-n3" RELATED [GOC:sl] +synonym: "response to leukocyte interferon" EXACT [GOC:sl] +synonym: "response to lymphoblast interferon" EXACT [GOC:sl] +synonym: "response to lymphoblastoid interferon" EXACT [GOC:sl] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2010-04-16T10:57:16Z + +[Term] +id: GO:0035456 +name: response to interferon-beta +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon." [GOC:sl, PMID:9561374, PR:000008924] +synonym: "response to beta-1 interferon" RELATED [GOC:sl] +synonym: "response to fiblaferon" EXACT [GOC:sl] +synonym: "response to fibroblast interferon" EXACT [GOC:sl] +synonym: "response to interferon beta" EXACT [GOC:hp, PR:000008924] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2010-04-16T11:06:12Z + +[Term] +id: GO:0035457 +name: cellular response to interferon-alpha +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon." [GOC:sl, PR:000024938] +synonym: "cellular response to interferon alfa-n1" RELATED [GOC:sl] +synonym: "cellular response to interferon alfa-n3" RELATED [GOC:sl] +synonym: "cellular response to leukocyte interferon" EXACT [GOC:sl] +synonym: "cellular response to lymphoblast interferon" EXACT [GOC:sl] +synonym: "cellular response to lymphoblastoid interferon" EXACT [GOC:sl] +is_a: GO:0035455 ! response to interferon-alpha +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2010-04-16T11:08:29Z + +[Term] +id: GO:0035458 +name: cellular response to interferon-beta +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon." [GOC:sl, PR:000024939] +synonym: "cellular response to beta-1 interferon" RELATED [GOC:sl] +synonym: "cellular response to fiblaferon" EXACT [GOC:sl] +synonym: "cellular response to fibroblast interferon" EXACT [GOC:sl] +is_a: GO:0035456 ! response to interferon-beta +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2010-04-16T11:10:40Z + +[Term] +id: GO:0035459 +name: vesicle cargo loading +namespace: biological_process +def: "The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle." [GOC:bf, GOC:lb] +synonym: "cargo loading into vesicle" EXACT [] +synonym: "cargo selection" EXACT [GOC:vw] +is_a: GO:0006810 ! transport +relationship: part_of GO:0016192 ! vesicle-mediated transport +created_by: bf +creation_date: 2010-04-16T01:14:06Z + +[Term] +id: GO:0035460 +name: L-ascorbate 6-phosphate lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate." [PMID:18097099, PMID:20359483] +xref: RHEA:28803 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: bf +creation_date: 2010-04-16T02:05:41Z + +[Term] +id: GO:0035461 +name: vitamin transmembrane transport +namespace: biological_process +def: "The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:bf] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "vitamin membrane transport" EXACT [] +is_a: GO:0051180 ! vitamin transport +is_a: GO:0055085 ! transmembrane transport +created_by: bf +creation_date: 2010-04-19T10:21:41Z + +[Term] +id: GO:0035462 +name: determination of left/right asymmetry in diencephalon +namespace: biological_process +def: "The establishment of the diencephalon with respect to the left and right halves." [GOC:dgh, PMID:15084459] +is_a: GO:0035545 ! determination of left/right asymmetry in nervous system +relationship: part_of GO:0021536 ! diencephalon development +created_by: bf +creation_date: 2010-04-19T11:50:11Z + +[Term] +id: GO:0035463 +name: transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves." [GOC:dgh, GOC:signaling] +synonym: "TGF-beta receptor signaling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "TGF-beta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "TGFbeta receptor signaling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "TGFbeta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007368 ! determination of left/right symmetry +created_by: bf +creation_date: 2010-04-19T01:19:20Z + +[Term] +id: GO:0035464 +name: regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves." [GOC:dgh] +synonym: "regulation of TGF-beta receptor signaling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "regulation of TGF-beta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "regulation of TGFbeta receptor signaling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "regulation of TGFbeta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +synonym: "regulation of transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry" EXACT [] +is_a: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035463 ! transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry +relationship: regulates GO:0035463 ! transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry +created_by: bf +creation_date: 2010-04-19T01:31:56Z + +[Term] +id: GO:0035465 +name: obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves." [GOC:dgh, PMID:15084459] +comment: This term was made obsolete because it describes regulation of the nodal signaling pathway. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm. +synonym: "regulation of TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "regulation of TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "regulation of TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "regulation of TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +synonym: "regulation of transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [] +is_obsolete: true +replaced_by: GO:1900175 +created_by: bf +creation_date: 2010-04-19T01:36:23Z + +[Term] +id: GO:0035469 +name: determination of pancreatic left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism." [GOC:dgh, PMID:12702646] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0031016 ! pancreas development +created_by: bf +creation_date: 2010-04-22T10:47:15Z + +[Term] +id: GO:0035470 +name: positive regulation of vascular wound healing +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:rph] +is_a: GO:0045766 ! positive regulation of angiogenesis +is_a: GO:0061043 ! regulation of vascular wound healing +is_a: GO:0090303 ! positive regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061042 ! vascular wound healing +relationship: positively_regulates GO:0061042 ! vascular wound healing +created_by: bf +creation_date: 2010-04-22T10:49:09Z + +[Term] +id: GO:0035471 +name: luteinizing hormone signaling pathway involved in ovarian follicle development +namespace: biological_process +def: "The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure." [GOC:bf] +synonym: "luteinizing hormone signalling pathway involved in ovarian follicle development" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0042700 ! luteinizing hormone signaling pathway +intersection_of: GO:0042700 ! luteinizing hormone signaling pathway +intersection_of: part_of GO:0001541 ! ovarian follicle development +relationship: part_of GO:0001541 ! ovarian follicle development +created_by: bf +creation_date: 2010-04-22T04:43:20Z + +[Term] +id: GO:0035472 +name: choriogonadotropin hormone receptor activity +namespace: molecular_function +def: "Combining with the choriogonadotropin hormone to initiate a change in cell activity." [GOC:bf, ISBN:0198506732, PMID:1922095] +synonym: "CG receptor activity" EXACT [ISBN:0198506732] +synonym: "chorio-gonadotrophin receptor activity" EXACT [ISBN:0198506732] +synonym: "chorionic gonadotropin hormone receptor" EXACT [ISBN:0198506732] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: has_part GO:0038106 ! choriogonadotropin hormone binding +created_by: bf +creation_date: 2010-04-22T04:49:57Z + +[Term] +id: GO:0035473 +name: lipase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any lipase." [GOC:BHF] +is_a: GO:0019899 ! enzyme binding +created_by: bf +creation_date: 2010-04-22T05:28:52Z + +[Term] +id: GO:0035474 +name: selective angioblast sprouting +namespace: biological_process +def: "The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel." [GOC:dgh, PMID:19815777] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048514 ! blood vessel morphogenesis +created_by: bf +creation_date: 2010-04-23T10:03:55Z + +[Term] +id: GO:0035475 +name: angioblast cell migration involved in selective angioblast sprouting +namespace: biological_process +def: "The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations." [GOC:dgh, PMID:19815777] +is_a: GO:0035476 ! angioblast cell migration +intersection_of: GO:0035476 ! angioblast cell migration +intersection_of: part_of GO:0035474 ! selective angioblast sprouting +relationship: part_of GO:0035474 ! selective angioblast sprouting +created_by: bf +creation_date: 2010-04-23T10:04:30Z + +[Term] +id: GO:0035476 +name: angioblast cell migration +namespace: biological_process +def: "The orderly movement of angioblasts, cells involved in blood vessel morphogenesis." [GOC:dgh, PMID:19815777] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0048514 ! blood vessel morphogenesis +created_by: bf +creation_date: 2010-04-23T10:06:32Z + +[Term] +id: GO:0035477 +name: regulation of angioblast cell migration involved in selective angioblast sprouting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting." [GOC:dgh, PMID:19815777] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:1901342 ! regulation of vasculature development +relationship: regulates GO:0035475 ! angioblast cell migration involved in selective angioblast sprouting +created_by: bf +creation_date: 2010-04-23T10:08:28Z + +[Term] +id: GO:0035478 +name: chylomicron binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE." [GOC:BHF, http://www.britannica.com/EBchecked/topic/117461/chylomicron] +is_a: GO:0071813 ! lipoprotein particle binding +created_by: bf +creation_date: 2010-04-23T10:18:52Z + +[Term] +id: GO:0035479 +name: angioblast cell migration from lateral mesoderm to midline +namespace: biological_process +def: "The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature." [GOC:dgh, PMID:11861480] +is_a: GO:0035476 ! angioblast cell migration +created_by: bf +creation_date: 2010-04-23T10:38:05Z + +[Term] +id: GO:0035480 +name: regulation of Notch signaling pathway involved in heart induction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction." [GOC:BHF] +synonym: "regulation of Notch signalling pathway involved in heart induction" EXACT [GOC:mah] +is_a: GO:0008593 ! regulation of Notch signaling pathway +is_a: GO:0090381 ! regulation of heart induction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003137 ! Notch signaling pathway involved in heart induction +relationship: regulates GO:0003137 ! Notch signaling pathway involved in heart induction +created_by: bf +creation_date: 2010-04-23T10:40:48Z + +[Term] +id: GO:0035481 +name: positive regulation of Notch signaling pathway involved in heart induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction." [GOC:BHF] +synonym: "positive regulation of Notch signalling pathway involved in heart induction" EXACT [GOC:mah] +is_a: GO:0035480 ! regulation of Notch signaling pathway involved in heart induction +is_a: GO:0045747 ! positive regulation of Notch signaling pathway +is_a: GO:1901321 ! positive regulation of heart induction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003137 ! Notch signaling pathway involved in heart induction +relationship: positively_regulates GO:0003137 ! Notch signaling pathway involved in heart induction +created_by: bf +creation_date: 2010-04-23T10:41:04Z + +[Term] +id: GO:0035482 +name: gastric motility +namespace: biological_process +def: "The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum." [GOC:cy, ISBN:9781416032458, PMID:16139031] +is_a: GO:0022600 ! digestive system process +created_by: bf +creation_date: 2010-04-23T10:44:59Z + +[Term] +id: GO:0035483 +name: gastric emptying +namespace: biological_process +def: "The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum." [GOC:cy, ISBN:9781416032458] +is_a: GO:0035482 ! gastric motility +created_by: bf +creation_date: 2010-04-23T10:51:33Z + +[Term] +id: GO:0035484 +name: adenine/adenine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing an A/A mispair." [GOC:bf, GOC:jh] +synonym: "A/A mispair binding" EXACT [GOC:jh] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T10:54:52Z + +[Term] +id: GO:0035485 +name: adenine/guanine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing an A/G mispair." [GOC:bf, GOC:jh] +synonym: "A/G mispair binding" EXACT [GOC:jh] +synonym: "G/A mispair binding" RELATED [GOC:bf] +synonym: "guanine-adenine mispair binding" EXACT [GOC:bf] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T10:55:43Z + +[Term] +id: GO:0035486 +name: cytosine/cytosine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a C/C mispair." [GOC:bf, GOC:jh] +synonym: "C/C mispair binding" EXACT [GOC:jh] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T10:56:10Z + +[Term] +id: GO:0035487 +name: thymine/thymine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a T/T mispair." [GOC:bf, GOC:jh] +synonym: "T/T mispair binding" EXACT [] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T10:56:37Z + +[Term] +id: GO:0035488 +name: cytosine/thymine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a C/T mispair." [GOC:bf, GOC:jh] +synonym: "C/T mispair binding" EXACT [GOC:jh] +synonym: "T/C mispair binding" EXACT [GOC:bf] +synonym: "thymine/cytosine mispair binding" EXACT [GOC:bf] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T10:57:13Z + +[Term] +id: GO:0035489 +name: guanine/guanine mispair binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA containing a G/G mispair." [GOC:bf, GOC:jh] +synonym: "G/G mispair binding" EXACT [GOC:jh] +is_a: GO:0030983 ! mismatched DNA binding +created_by: bf +creation_date: 2010-04-23T11:16:55Z + +[Term] +id: GO:0035490 +name: regulation of leukotriene production involved in inflammatory response +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf] +is_a: GO:0050727 ! regulation of inflammatory response +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002540 ! leukotriene production involved in inflammatory response +relationship: regulates GO:0002540 ! leukotriene production involved in inflammatory response +created_by: bf +creation_date: 2010-04-26T10:49:22Z + +[Term] +id: GO:0035491 +name: positive regulation of leukotriene production involved in inflammatory response +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf] +is_a: GO:0035490 ! regulation of leukotriene production involved in inflammatory response +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002540 ! leukotriene production involved in inflammatory response +relationship: positively_regulates GO:0002540 ! leukotriene production involved in inflammatory response +created_by: bf +creation_date: 2010-04-26T10:50:14Z + +[Term] +id: GO:0035492 +name: negative regulation of leukotriene production involved in inflammatory response +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response." [GOC:bf] +is_a: GO:0035490 ! regulation of leukotriene production involved in inflammatory response +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002540 ! leukotriene production involved in inflammatory response +relationship: negatively_regulates GO:0002540 ! leukotriene production involved in inflammatory response +created_by: bf +creation_date: 2010-04-26T10:50:55Z + +[Term] +id: GO:0035493 +name: SNARE complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb, PMID:10872468] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0006906 ! vesicle fusion +created_by: bf +creation_date: 2010-04-26T02:50:52Z + +[Term] +id: GO:0035494 +name: SNARE complex disassembly +namespace: biological_process +def: "The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb, PMID:11697877] +is_a: GO:0043624 ! cellular protein complex disassembly +relationship: part_of GO:0016192 ! vesicle-mediated transport +created_by: bf +creation_date: 2010-04-26T02:54:17Z + +[Term] +id: GO:0035495 +name: regulation of SNARE complex disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035494 ! SNARE complex disassembly +relationship: regulates GO:0035494 ! SNARE complex disassembly +created_by: bf +creation_date: 2010-04-26T02:56:53Z + +[Term] +id: GO:0035496 +name: lipopolysaccharide-1,5-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide." [PMID:11304545] +synonym: "LPS-1,5-galactosyltransferase activity" EXACT [PMID:11304545] +synonym: "UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase" EXACT [PMID:11304545] +is_a: GO:0035250 ! UDP-galactosyltransferase activity +created_by: bf +creation_date: 2010-04-26T03:00:21Z + +[Term] +id: GO:0035497 +name: cAMP response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP." [PMID:2875459, PMID:2900470] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "cAMP-responsive element binding" EXACT [PMID:2875459] +synonym: "CRE binding" EXACT [PMID:2900470] +synonym: "cyclic AMP response element binding" EXACT [PMID:2900470] +synonym: "cyclic-AMP response element binding" EXACT [PMID:2900470] +synonym: "cyclic-AMP-responsive element binding" EXACT [PMID:2875459] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: bf +creation_date: 2010-04-29T09:26:47Z + +[Term] +id: GO:0035498 +name: carnosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine)." [PMID:20097752] +synonym: "carnosine metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +created_by: bf +creation_date: 2010-04-29T01:19:52Z + +[Term] +id: GO:0035499 +name: carnosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine)." [EC:6.3.2.11, PMID:20097752] +synonym: "carnosine anabolism" EXACT [] +synonym: "carnosine biosynthesis" EXACT [] +synonym: "carnosine formation" EXACT [] +synonym: "carnosine synthesis" EXACT [] +is_a: GO:0035498 ! carnosine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +created_by: bf +creation_date: 2010-04-29T01:20:56Z + +[Term] +id: GO:0035500 +name: MH2 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers." [GOC:curators] +synonym: "MAD homology 2 domain binding" EXACT [Pfam:PF03166] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2010-04-29T03:14:32Z + +[Term] +id: GO:0035501 +name: MH1 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors." [Pfam:PF03165] +synonym: "MAD homology 1 domain binding" EXACT [Pfam:PF03165] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2010-04-29T03:17:27Z + +[Term] +id: GO:0035502 +name: metanephric part of ureteric bud development +namespace: biological_process +def: "The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0001657 ! ureteric bud development +relationship: part_of GO:0003338 ! metanephros morphogenesis +created_by: bf +creation_date: 2010-04-29T03:22:21Z + +[Term] +id: GO:0035503 +name: ureter part of ureteric bud development +namespace: biological_process +def: "The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0001657 ! ureteric bud development +relationship: part_of GO:0072197 ! ureter morphogenesis +created_by: bf +creation_date: 2010-04-29T03:23:42Z + +[Term] +id: GO:0035504 +name: regulation of myosin light chain kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004687 ! myosin light chain kinase activity +relationship: regulates GO:0004687 ! myosin light chain kinase activity +created_by: bf +creation_date: 2010-04-30T10:47:11Z + +[Term] +id: GO:0035505 +name: positive regulation of myosin light chain kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0035504 ! regulation of myosin light chain kinase activity +is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004687 ! myosin light chain kinase activity +relationship: positively_regulates GO:0004687 ! myosin light chain kinase activity +created_by: bf +creation_date: 2010-04-30T10:48:09Z + +[Term] +id: GO:0035506 +name: negative regulation of myosin light chain kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0035504 ! regulation of myosin light chain kinase activity +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004687 ! myosin light chain kinase activity +relationship: negatively_regulates GO:0004687 ! myosin light chain kinase activity +created_by: bf +creation_date: 2010-04-30T10:49:21Z + +[Term] +id: GO:0035507 +name: regulation of myosin-light-chain-phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050115 ! myosin-light-chain-phosphatase activity +relationship: regulates GO:0050115 ! myosin-light-chain-phosphatase activity +created_by: bf +creation_date: 2010-04-30T10:53:38Z + +[Term] +id: GO:0035508 +name: positive regulation of myosin-light-chain-phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0032516 ! positive regulation of phosphoprotein phosphatase activity +is_a: GO:0035507 ! regulation of myosin-light-chain-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050115 ! myosin-light-chain-phosphatase activity +relationship: positively_regulates GO:0050115 ! myosin-light-chain-phosphatase activity +created_by: bf +creation_date: 2010-04-30T10:55:05Z + +[Term] +id: GO:0035509 +name: negative regulation of myosin-light-chain-phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity." [GOC:bf, GOC:go_curators] +is_a: GO:0032515 ! negative regulation of phosphoprotein phosphatase activity +is_a: GO:0035507 ! regulation of myosin-light-chain-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050115 ! myosin-light-chain-phosphatase activity +relationship: negatively_regulates GO:0050115 ! myosin-light-chain-phosphatase activity +created_by: bf +creation_date: 2010-04-30T10:56:34Z + +[Term] +id: GO:0035510 +name: DNA dealkylation +namespace: biological_process +def: "The removal of an alkyl group from one or more nucleotides within an DNA molecule." [GOC:bf] +is_a: GO:0006304 ! DNA modification +created_by: bf +creation_date: 2010-04-30T02:20:08Z + +[Term] +id: GO:0035511 +name: oxidative DNA demethylation +namespace: biological_process +def: "Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698] +is_a: GO:0070989 ! oxidative demethylation +is_a: GO:0080111 ! DNA demethylation +created_by: bf +creation_date: 2010-04-30T02:22:44Z + +[Term] +id: GO:0035512 +name: hydrolytic DNA demethylation +namespace: biological_process +def: "The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule." [GOC:bf] +is_a: GO:0080111 ! DNA demethylation +created_by: bf +creation_date: 2010-04-30T02:24:21Z + +[Term] +id: GO:0035513 +name: oxidative RNA demethylation +namespace: biological_process +def: "The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698] +is_a: GO:0009451 ! RNA modification +is_a: GO:0070989 ! oxidative demethylation +created_by: bf +creation_date: 2010-04-30T02:25:35Z + +[Term] +id: GO:0035514 +name: DNA demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule." [GOC:bf] +is_a: GO:0032451 ! demethylase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0080111 ! DNA demethylation +created_by: bf +creation_date: 2010-04-30T02:36:43Z + +[Term] +id: GO:0035515 +name: oxidative RNA demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698] +synonym: "2-oxoglutarate-dependent RNA demethylase" EXACT [PMID:17991826] +xref: Reactome:R-HSA-8857692 "RNA demethylases demethylate N6-methyladenosine RNA" +is_a: GO:0016491 ! oxidoreductase activity +is_a: GO:0032451 ! demethylase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +relationship: part_of GO:0035513 ! oxidative RNA demethylation +created_by: bf +creation_date: 2010-04-30T02:37:08Z + +[Term] +id: GO:0035516 +name: oxidative DNA demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [PMID:12594517, PMID:16482161, PMID:18775698] +synonym: "2-oxoglutarate-dependent DNA demethylase" EXACT [PMID:17991826] +is_a: GO:0016491 ! oxidoreductase activity +is_a: GO:0035514 ! DNA demethylase activity +relationship: part_of GO:0035511 ! oxidative DNA demethylation +created_by: bf +creation_date: 2010-04-30T02:38:16Z + +[Term] +id: GO:0035517 +name: PR-DUB complex +namespace: cellular_component +def: "A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively." [PMID:20436459] +synonym: "Polycomb repressive deubiquitinase complex" EXACT [PMID:20436459] +is_a: GO:0031519 ! PcG protein complex +created_by: bf +creation_date: 2010-05-04T04:19:02Z + +[Term] +id: GO:0035518 +name: histone H2A monoubiquitination +namespace: biological_process +def: "The modification of histone H2A by addition of a single ubiquitin group." [PMID:18206970] +is_a: GO:0010390 ! histone monoubiquitination +is_a: GO:0033522 ! histone H2A ubiquitination +created_by: bf +creation_date: 2010-05-04T04:22:09Z + +[Term] +id: GO:0035519 +name: protein K29-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation." [PMID:17028573] +synonym: "protein K29-linked polyubiquitination" EXACT [GOC:mah] +is_a: GO:0000209 ! protein polyubiquitination +created_by: bf +creation_date: 2010-05-04T04:25:48Z + +[Term] +id: GO:0035520 +name: monoubiquitinated protein deubiquitination +namespace: biological_process +def: "The removal of the ubiquitin group from a monoubiquitinated protein." [GOC:bf] +synonym: "monoubiquitinated protein deubiquitinylation" EXACT [] +synonym: "monoubiquitinated protein deubiquitylation" EXACT [] +is_a: GO:0016579 ! protein deubiquitination +created_by: bf +creation_date: 2010-05-04T04:28:38Z + +[Term] +id: GO:0035521 +name: monoubiquitinated histone deubiquitination +namespace: biological_process +def: "The removal of the ubiquitin group from a monoubiquitinated histone protein." [GOC:bf, PMID:20436459] +synonym: "monoubiquitinated histone deubiquitinylation" EXACT [] +synonym: "monoubiquitinated histone deubiquitylation" EXACT [] +is_a: GO:0016578 ! histone deubiquitination +is_a: GO:0035520 ! monoubiquitinated protein deubiquitination +created_by: bf +creation_date: 2010-05-04T04:32:04Z + +[Term] +id: GO:0035522 +name: monoubiquitinated histone H2A deubiquitination +namespace: biological_process +def: "The removal of the ubiquitin group from a monoubiquitinated histone H2A protein." [GOC:bf, PMID:18226187, PMID:20436459] +synonym: "monoubiquitinated histone H2A deubiquitinylation" EXACT [] +synonym: "monoubiquitinated histone H2A deubiquitylation" EXACT [] +is_a: GO:0035521 ! monoubiquitinated histone deubiquitination +created_by: bf +creation_date: 2010-05-04T04:32:53Z + +[Term] +id: GO:0035523 +name: protein K29-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein." [GOC:bf] +synonym: "protein K29-linked deubiquitinylation" EXACT [] +synonym: "protein K29-linked deubiquitylation" EXACT [] +is_a: GO:0016579 ! protein deubiquitination +created_by: bf +creation_date: 2010-05-04T04:33:27Z + +[Term] +id: GO:0035524 +name: proline transmembrane transport +namespace: biological_process +def: "The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "proline membrane transport" EXACT [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015824 ! proline transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: bf +creation_date: 2010-05-04T04:52:46Z + +[Term] +id: GO:0035525 +name: NF-kappaB p50/p65 complex +namespace: cellular_component +def: "A heterodimer of NF-kappa B p50 and p65 subunits." [GO:add, PMID:20393192, PMID:9299584] +comment: Note that the p50 subunit is encoded by NFKB1 gene in human and the p65 subunit is encoded by the RELA gene in human. Similar nomenclature is used in other vertebrate species. The p50 subunit has a precursor form p105 in some publications. +synonym: "NF-kappa B1/p65 complex" EXACT [PMID:9299584] +synonym: "NF-kappa B1/RelA complex" EXACT [PMID:9299584] +synonym: "NF-kappa p105/p65 complex" RELATED [PMID:9299584] +synonym: "NF-kappa p105/RelA complex" RELATED [PMID:9299584] +synonym: "NF-kappa p50/RelA complex" EXACT [PMID:9299584] +is_a: GO:0071159 ! NF-kappaB complex +created_by: bf +creation_date: 2010-05-05T10:45:13Z + +[Term] +id: GO:0035526 +name: retrograde transport, plasma membrane to Golgi +namespace: biological_process +def: "The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles." [GOC:lb, PMID:17488291] +is_a: GO:0016192 ! vesicle-mediated transport +created_by: bf +creation_date: 2010-05-05T10:52:49Z + +[Term] +id: GO:0035527 +name: 3-hydroxypropionate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH." [RHEA:26438] +synonym: "3-hydroxypropanoate dehydrogenase (NADP+) activity" EXACT [] +synonym: "3-hydroxypropanoate:NADP+ oxidoreductase" EXACT [EC:1.1.1.298] +synonym: "3-hydroxypropionate:NADP+ oxidoreductase" EXACT [EC:1.1.1.298] +xref: EC:1.1.1.298 +xref: KEGG_REACTION:R09289 +xref: MetaCyc:RXN-8974 +xref: RHEA:26438 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2010-05-05T10:55:07Z + +[Term] +id: GO:0035528 +name: UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin." [GOC:bf] +synonym: "UDP-GlcNAc biosynthesis involved in chitin biosynthesis" EXACT [] +synonym: "UDP-GlcNAc biosynthetic process involved in chitin biosynthesis" EXACT [] +synonym: "UDP-GlcNAc biosynthetic process involved in chitin biosynthetic process" EXACT [] +synonym: "UDP-N-acetylglucosamine anabolism involved in chitin biosynthesis" EXACT [] +synonym: "UDP-N-acetylglucosamine biosynthetic process involved in chitin biosynthetic process" EXACT [] +synonym: "UDP-N-acetylglucosamine formation involved in chitin biosynthesis" EXACT [] +synonym: "UDP-N-acetylglucosamine synthesis involved in chitin biosynthesis" EXACT [] +is_a: GO:0006048 ! UDP-N-acetylglucosamine biosynthetic process +intersection_of: GO:0006048 ! UDP-N-acetylglucosamine biosynthetic process +intersection_of: part_of GO:0006031 ! chitin biosynthetic process +relationship: part_of GO:0006031 ! chitin biosynthetic process +created_by: bf +creation_date: 2010-05-05T04:49:49Z + +[Term] +id: GO:0035529 +name: NADH pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+." [MetaCyc:RXN0-4401, PMID:12399474, PMID:20181750] +synonym: "NADH diphosphatase activity" EXACT [] +synonym: "NADH pyrophosphohydrolase activity" EXACT [] +xref: EC:3.6.1.9 +xref: KEGG_REACTION:R00103 +xref: MetaCyc:RXN0-4401 +xref: Reactome:R-HSA-6809287 "NUDT12 hydrolyses NADH to NMNH" +is_a: GO:0004551 ! nucleotide diphosphatase activity +created_by: bf +creation_date: 2010-05-05T04:55:10Z + +[Term] +id: GO:0035530 +name: chemokine (C-C motif) ligand 6 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, PMID:19812544] +synonym: "CCL6 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: bf +creation_date: 2010-05-07T10:21:15Z + +[Term] +id: GO:0035531 +name: regulation of chemokine (C-C motif) ligand 6 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf] +synonym: "regulation of CCL6 production" EXACT [] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +relationship: regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +created_by: bf +creation_date: 2010-05-07T10:22:51Z + +[Term] +id: GO:0035532 +name: negative regulation of chemokine (C-C motif) ligand 6 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf] +synonym: "negative regulation of CCL6 production" EXACT [] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0035531 ! regulation of chemokine (C-C motif) ligand 6 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +relationship: negatively_regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +created_by: bf +creation_date: 2010-05-07T10:23:40Z + +[Term] +id: GO:0035533 +name: positive regulation of chemokine (C-C motif) ligand 6 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)." [GOC:add, GOC:bf] +synonym: "positive regulation of CCL6 production" EXACT [] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0035531 ! regulation of chemokine (C-C motif) ligand 6 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +relationship: positively_regulates GO:0035530 ! chemokine (C-C motif) ligand 6 production +created_by: bf +creation_date: 2010-05-07T10:24:21Z + +[Term] +id: GO:0035534 +name: chemokine (C-C motif) ligand 6 secretion +namespace: biological_process +def: "The regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:amm] +synonym: "CCL6 secretion" EXACT [] +is_a: GO:0090195 ! chemokine secretion +relationship: part_of GO:0035530 ! chemokine (C-C motif) ligand 6 production +created_by: bf +creation_date: 2010-05-07T10:28:11Z + +[Term] +id: GO:0035535 +name: regulation of chemokine (C-C motif) ligand 6 secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf] +synonym: "regulation of CCL6 secretion" EXACT [] +is_a: GO:0035531 ! regulation of chemokine (C-C motif) ligand 6 production +is_a: GO:0090196 ! regulation of chemokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +relationship: regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +created_by: bf +creation_date: 2010-05-07T10:29:40Z + +[Term] +id: GO:0035536 +name: negative regulation of chemokine (C-C motif) ligand 6 secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf] +synonym: "negative regulation of CCL6 secretion" EXACT [] +is_a: GO:0035532 ! negative regulation of chemokine (C-C motif) ligand 6 production +is_a: GO:0035535 ! regulation of chemokine (C-C motif) ligand 6 secretion +is_a: GO:0090198 ! negative regulation of chemokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +relationship: negatively_regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +created_by: bf +creation_date: 2010-05-07T10:30:14Z + +[Term] +id: GO:0035537 +name: positive regulation of chemokine (C-C motif) ligand 6 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell." [GOC:add, GOC:bf] +synonym: "positive regulation of CCL6 secretion" EXACT [] +is_a: GO:0035533 ! positive regulation of chemokine (C-C motif) ligand 6 production +is_a: GO:0035535 ! regulation of chemokine (C-C motif) ligand 6 secretion +is_a: GO:0090197 ! positive regulation of chemokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +relationship: positively_regulates GO:0035534 ! chemokine (C-C motif) ligand 6 secretion +created_by: bf +creation_date: 2010-05-07T10:31:19Z + +[Term] +id: GO:0035538 +name: carbohydrate response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes." [GOC:BHF, PMID:20001964] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "ChoRE binding" EXACT [PMID:20001964] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: bf +creation_date: 2010-05-07T10:48:30Z + +[Term] +id: GO:0035539 +name: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA." [PMID:17804481, PMID:7782328, PMID:7859359] +synonym: "8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity" EXACT [PMID:17804481] +synonym: "8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity" EXACT [PMID:17804481] +synonym: "8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity" EXACT [PMID:7782328] +synonym: "8-oxo-dGTP pyrophosphohydrolase activity" EXACT [PMID:17804481] +synonym: "8-oxo-dGTPase activity" EXACT [PMID:7782328] +xref: Reactome:R-HSA-2395849 "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP" +xref: Reactome:R-HSA-2395869 "NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP" +xref: RHEA:31575 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2010-05-07T10:54:19Z + +[Term] +id: GO:0035540 +name: positive regulation of SNARE complex disassembly +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0035495 ! regulation of SNARE complex disassembly +is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035494 ! SNARE complex disassembly +relationship: positively_regulates GO:0035494 ! SNARE complex disassembly +created_by: bf +creation_date: 2010-05-10T01:42:21Z + +[Term] +id: GO:0035541 +name: negative regulation of SNARE complex disassembly +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0035495 ! regulation of SNARE complex disassembly +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035494 ! SNARE complex disassembly +relationship: negatively_regulates GO:0035494 ! SNARE complex disassembly +created_by: bf +creation_date: 2010-05-10T01:42:47Z + +[Term] +id: GO:0035542 +name: regulation of SNARE complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0031338 ! regulation of vesicle fusion +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035493 ! SNARE complex assembly +relationship: regulates GO:0035493 ! SNARE complex assembly +created_by: bf +creation_date: 2010-05-10T01:49:35Z + +[Term] +id: GO:0035543 +name: positive regulation of SNARE complex assembly +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0031340 ! positive regulation of vesicle fusion +is_a: GO:0035542 ! regulation of SNARE complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035493 ! SNARE complex assembly +relationship: positively_regulates GO:0035493 ! SNARE complex assembly +created_by: bf +creation_date: 2010-05-10T01:50:02Z + +[Term] +id: GO:0035544 +name: negative regulation of SNARE complex assembly +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers." [GOC:rb] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0031339 ! negative regulation of vesicle fusion +is_a: GO:0035542 ! regulation of SNARE complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035493 ! SNARE complex assembly +relationship: negatively_regulates GO:0035493 ! SNARE complex assembly +created_by: bf +creation_date: 2010-05-10T01:51:10Z + +[Term] +id: GO:0035545 +name: determination of left/right asymmetry in nervous system +namespace: biological_process +def: "The establishment of the nervous system with respect to the left and right halves." [GOC:kmv, PMID:17717195, PMID:19641012] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007399 ! nervous system development +created_by: bf +creation_date: 2010-05-11T01:53:33Z + +[Term] +id: GO:0035546 +name: interferon-beta secretion +namespace: biological_process +def: "The regulated release of interferon-beta from a cell." [GOC:add, GOC:bf] +synonym: "IFN-beta secretion" EXACT [] +synonym: "IFNB secretion" EXACT [GOC:mah] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0032608 ! interferon-beta production +created_by: bf +creation_date: 2010-05-12T10:04:11Z + +[Term] +id: GO:0035547 +name: regulation of interferon-beta secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf] +synonym: "regulation of IFN-beta secretion" EXACT [] +is_a: GO:0032648 ! regulation of interferon-beta production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035546 ! interferon-beta secretion +relationship: regulates GO:0035546 ! interferon-beta secretion +created_by: bf +creation_date: 2010-05-12T10:06:03Z + +[Term] +id: GO:0035548 +name: negative regulation of interferon-beta secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf] +synonym: "down regulation of interferon-beta secretion" EXACT [] +synonym: "down-regulation of interferon-beta secretion" EXACT [] +synonym: "downregulation of interferon-beta secretion" EXACT [] +synonym: "inhibition of interferon-beta secretion" NARROW [] +synonym: "negative regulation of IFN-beta secretion" EXACT [] +is_a: GO:0032688 ! negative regulation of interferon-beta production +is_a: GO:0035547 ! regulation of interferon-beta secretion +is_a: GO:0050710 ! negative regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035546 ! interferon-beta secretion +relationship: negatively_regulates GO:0035546 ! interferon-beta secretion +created_by: bf +creation_date: 2010-05-12T10:06:28Z + +[Term] +id: GO:0035549 +name: positive regulation of interferon-beta secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interferon-beta secretion." [GOC:add, GOC:bf] +synonym: "activation of interferon-beta secretion" NARROW [] +synonym: "positive regulation of IFN-beta secretion" EXACT [] +synonym: "stimulation of interferon-beta secretion" NARROW [] +synonym: "up regulation of interferon-beta secretion" EXACT [] +synonym: "up-regulation of interferon-beta secretion" EXACT [] +synonym: "upregulation of interferon-beta secretion" EXACT [] +is_a: GO:0032728 ! positive regulation of interferon-beta production +is_a: GO:0035547 ! regulation of interferon-beta secretion +is_a: GO:0050715 ! positive regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035546 ! interferon-beta secretion +relationship: positively_regulates GO:0035546 ! interferon-beta secretion +created_by: bf +creation_date: 2010-05-12T10:06:50Z + +[Term] +id: GO:0035550 +name: urease complex +namespace: cellular_component +def: "A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide)." [InterPro:IPR008221, PMID:2651866] +comment: Eukaryotic microorganisms, plants, and probably Gram-positive bacteria, possess a homopolymeric urease. In contrast, urease complexes from gram-negative bacteria studied thus far clearly possess three distinct subunits (alpha, beta and gamma). Tightly bound nickel is present in all urease complexes. +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2010-05-12T01:00:27Z + +[Term] +id: GO:0035551 +name: protein initiator methionine removal involved in protein maturation +namespace: biological_process +def: "Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein." [GOC:bf, GOC:hjd, GOC:vw] +is_a: GO:0016485 ! protein processing +is_a: GO:0070084 ! protein initiator methionine removal +intersection_of: GO:0070084 ! protein initiator methionine removal +intersection_of: part_of GO:0051604 ! protein maturation +relationship: part_of GO:0051604 ! protein maturation +created_by: bf +creation_date: 2010-05-13T04:29:05Z + +[Term] +id: GO:0035552 +name: oxidative single-stranded DNA demethylation +namespace: biological_process +def: "Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [GOC:BHF, GOC:rl, PMID:18775698] +synonym: "oxidative ssDNA demethylation" EXACT [] +is_a: GO:0035511 ! oxidative DNA demethylation +created_by: bf +creation_date: 2010-05-14T11:03:55Z + +[Term] +id: GO:0035553 +name: oxidative single-stranded RNA demethylation +namespace: biological_process +def: "Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms." [GOC:BHF, GOC:rl, PMID:18775698] +synonym: "oxidative ssRNA demethylation" EXACT [] +is_a: GO:0035513 ! oxidative RNA demethylation +created_by: bf +creation_date: 2010-05-14T11:05:17Z + +[Term] +id: GO:0035554 +name: termination of Roundabout signal transduction +namespace: biological_process +def: "The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated." [GOC:BHF, GOC:vk] +is_a: GO:0023021 ! termination of signal transduction +is_a: GO:0035387 ! negative regulation of Roundabout signaling pathway +relationship: part_of GO:0035385 ! Roundabout signaling pathway +created_by: bf +creation_date: 2010-05-14T11:08:12Z + +[Term] +id: GO:0035555 +name: obsolete initiation of Roundabout signal transduction +namespace: biological_process +def: "OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO)." [GOC:vk] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "initiation of Roundabout signal transduction" EXACT [] +is_obsolete: true +consider: GO:0035385 +consider: GO:0038023 +consider: GO:0048495 +created_by: bf +creation_date: 2010-05-14T11:10:20Z + +[Term] +id: GO:0035556 +name: intracellular signal transduction +namespace: biological_process +alt_id: GO:0007242 +alt_id: GO:0007243 +alt_id: GO:0023013 +alt_id: GO:0023034 +def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] +subset: goslim_drosophila +synonym: "intracellular protein kinase cascade" NARROW [GOC:signaling] +synonym: "intracellular signal transduction pathway" NARROW [] +synonym: "intracellular signaling cascade" RELATED [GOC:signaling] +synonym: "intracellular signaling chain" EXACT [ISBN:3527303782] +synonym: "intracellular signaling pathway" RELATED [] +synonym: "protein kinase cascade" NARROW [GOC:signaling] +synonym: "signal transduction via intracellular signaling cascade" RELATED [] +synonym: "signal transmission via intracellular cascade" NARROW [] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: occurs_in GO:0005622 ! intracellular +relationship: occurs_in GO:0005622 ! intracellular +created_by: bf +creation_date: 2010-05-14T01:14:37Z + +[Term] +id: GO:0035557 +name: obsolete intracellular signal transduction involved in cell surface receptor linked signaling +namespace: biological_process +def: "OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling, ISBN:3527303782] +comment: This term was made obsolete because the syntax of the term is incorrect. +synonym: "intracellular signal transduction involved in cell surface receptor linked signaling" EXACT [] +synonym: "intracellular signal transduction involved in cell surface receptor linked signalling" EXACT [GOC:mah] +synonym: "intracellular signaling cascade involved in cell surface receptor linked signaling" EXACT [] +synonym: "intracellular signaling chain involved in cell surface receptor signaling" EXACT [ISBN:3527303782] +is_obsolete: true +created_by: bf +creation_date: 2010-05-14T01:31:05Z + +[Term] +id: GO:0035558 +name: obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling +namespace: biological_process +def: "OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:signaling] +comment: This term was made obsolete because the syntax of the term is incorrect. +synonym: "phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling" EXACT [] +synonym: "phosphatidylinositol 3-kinase cascade involved in insulin receptor signalling" EXACT [] +synonym: "phosphoinositide 3-kinase cascade involved in insulin receptor signaling" EXACT [] +synonym: "phosphoinositide 3-kinase cascade involved in insulin receptor signalling" EXACT [GOC:mah] +synonym: "PI3K cascade involved in signaling from the insulin receptor" EXACT [] +is_obsolete: true +consider: GO:0038028 +created_by: bf +creation_date: 2010-05-14T01:34:38Z + +[Term] +id: GO:0035559 +name: obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling +namespace: biological_process +def: "OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:signaling] +comment: This term was made obsolete because the syntax of the term is incorrect. +synonym: "MAPKKK cascade involved in epidermal growth factor receptor signaling" EXACT [] +synonym: "MAPKKK cascade involved in epidermal growth factor receptor signalling" EXACT [GOC:mah] +synonym: "MAPKKK cascade involved in signaling from the EGFR" EXACT [] +is_obsolete: true +consider: GO:0038029 +created_by: bf +creation_date: 2010-05-14T01:53:15Z + +[Term] +id: GO:0035560 +name: pheophoridase activity +namespace: molecular_function +def: "Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a." [EC:3.1.1.82, PMID:16228561, RHEA:32483] +synonym: "phedase activity" EXACT [EC:3.1.1.82] +synonym: "PPD activity" EXACT [EC:3.1.1.82] +xref: EC:3.1.1.82 +xref: RHEA:32483 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: bf +creation_date: 2010-05-14T02:39:58Z + +[Term] +id: GO:0035561 +name: regulation of chromatin binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003682 ! chromatin binding +relationship: regulates GO:0003682 ! chromatin binding +created_by: bf +creation_date: 2010-05-19T10:28:36Z + +[Term] +id: GO:0035562 +name: negative regulation of chromatin binding +namespace: biological_process +def: "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130] +is_a: GO:0035561 ! regulation of chromatin binding +is_a: GO:0051100 ! negative regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003682 ! chromatin binding +relationship: negatively_regulates GO:0003682 ! chromatin binding +created_by: bf +creation_date: 2010-05-19T10:29:06Z + +[Term] +id: GO:0035563 +name: positive regulation of chromatin binding +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:bf, PMID:20404130] +is_a: GO:0035561 ! regulation of chromatin binding +is_a: GO:0051099 ! positive regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003682 ! chromatin binding +relationship: positively_regulates GO:0003682 ! chromatin binding +created_by: bf +creation_date: 2010-05-19T10:29:41Z + +[Term] +id: GO:0035564 +name: regulation of kidney size +namespace: biological_process +def: "Any process that modulates the size of a kidney." [GOC:bf] +is_a: GO:0090066 ! regulation of anatomical structure size +relationship: part_of GO:0060993 ! kidney morphogenesis +created_by: bf +creation_date: 2010-07-23T11:28:22Z + +[Term] +id: GO:0035565 +name: regulation of pronephros size +namespace: biological_process +def: "Any process that modulates the size of a pronephric kidney." [GOC:bf] +synonym: "regulation of pronephric kidney size" EXACT [GOC:bf] +is_a: GO:0035564 ! regulation of kidney size +relationship: part_of GO:0072114 ! pronephros morphogenesis +created_by: bf +creation_date: 2010-07-23T11:28:57Z + +[Term] +id: GO:0035566 +name: regulation of metanephros size +namespace: biological_process +def: "Any process that modulates the size of a metanephric kidney." [GOC:bf] +synonym: "regulation of metanephric kidney size" EXACT [GOC:bf] +is_a: GO:0035564 ! regulation of kidney size +relationship: part_of GO:0003338 ! metanephros morphogenesis +created_by: bf +creation_date: 2010-07-23T11:34:06Z + +[Term] +id: GO:0035567 +name: non-canonical Wnt signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin." [GOC:signaling] +comment: This term should only be used when Wnt receptor signaling occurs via a beta-catenin-independent route but the downstream effectors are unknown. If the downstream effectors are known, consider instead annotating to one of the children, or requesting a new term. +synonym: "beta-catenin-independent Wnt receptor signaling pathway" EXACT [GOC:signaling] +synonym: "non-canonical Wnt receptor signaling pathway" EXACT [] +synonym: "non-canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "non-canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +created_by: bf +creation_date: 2010-07-23T02:26:01Z + +[Term] +id: GO:0035568 +name: N-terminal peptidyl-proline methylation +namespace: biological_process +def: "The methylation of the N-terminal proline of proteins." [PMID:20668449, RESID:AA0419] +xref: RESID:AA0419 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018208 ! peptidyl-proline modification +created_by: bf +creation_date: 2010-08-06T01:52:43Z + +[Term] +id: GO:0035569 +name: obsolete N-terminal peptidyl-proline trimethylation +namespace: biological_process +def: "OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline." [PMID:20668449] +comment: This term was made obsolete because N-terminal proline residues cannot be trimethylated. +synonym: "N-terminal peptidyl-proline trimethylation" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2010-08-06T01:55:19Z + +[Term] +id: GO:0035570 +name: N-terminal peptidyl-serine methylation +namespace: biological_process +def: "The methylation of the N-terminal serine of proteins." [PMID:20668449] +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018209 ! peptidyl-serine modification +created_by: bf +creation_date: 2010-08-06T01:58:11Z + +[Term] +id: GO:0035571 +name: N-terminal peptidyl-serine monomethylation +namespace: biological_process +def: "The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine." [PMID:20668449] +is_a: GO:0035570 ! N-terminal peptidyl-serine methylation +created_by: bf +creation_date: 2010-08-06T01:58:56Z + +[Term] +id: GO:0035572 +name: N-terminal peptidyl-serine dimethylation +namespace: biological_process +def: "The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine." [PMID:20668449] +is_a: GO:0035570 ! N-terminal peptidyl-serine methylation +created_by: bf +creation_date: 2010-08-06T02:00:17Z + +[Term] +id: GO:0035573 +name: N-terminal peptidyl-serine trimethylation +namespace: biological_process +def: "The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine." [PMID:20668449] +is_a: GO:0035570 ! N-terminal peptidyl-serine methylation +created_by: bf +creation_date: 2010-08-06T02:00:42Z + +[Term] +id: GO:0035574 +name: histone H4-K20 demethylation +namespace: biological_process +def: "The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone." [GOC:sp, PMID:20622853] +is_a: GO:0070076 ! histone lysine demethylation +created_by: bf +creation_date: 2010-08-13T10:50:06Z + +[Term] +id: GO:0035575 +name: histone demethylase activity (H4-K20 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein." [PMID:20622853] +xref: Reactome:R-HSA-2172678 "PHF8 demethylates histone H4K20me1" +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0035574 ! histone H4-K20 demethylation +created_by: bf +creation_date: 2010-08-13T10:51:13Z + +[Term] +id: GO:0035576 +name: retinoic acid receptor signaling pathway involved in pronephric field specification +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop." [GOC:bf, PMID:16979153, PMID:19909807] +synonym: "retinoic acid receptor signalling pathway involved in pronephric field specification" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0039003 ! pronephric field specification +relationship: part_of GO:0039003 ! pronephric field specification +created_by: bf +creation_date: 2010-10-05T01:19:35Z + +[Term] +id: GO:0035577 +name: azurophil granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:bf, PMID:17152095] +synonym: "primary granule membrane" EXACT [] +is_a: GO:0005765 ! lysosomal membrane +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042582 ! azurophil granule +created_by: bf +creation_date: 2010-10-05T01:29:10Z + +[Term] +id: GO:0035578 +name: azurophil granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:bf, PMID:17152095] +synonym: "primary granule lumen" EXACT [] +is_a: GO:0005775 ! vacuolar lumen +is_a: GO:0034774 ! secretory granule lumen +relationship: part_of GO:0042582 ! azurophil granule +created_by: bf +creation_date: 2010-10-05T01:30:33Z + +[Term] +id: GO:0035579 +name: specific granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:bf, PMID:7334549] +synonym: "secondary granule membrane" EXACT [] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042581 ! specific granule +created_by: bf +creation_date: 2010-10-05T01:32:47Z + +[Term] +id: GO:0035580 +name: specific granule lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:bf, PMID:7334549] +synonym: "secondary granule lumen" EXACT [] +is_a: GO:0034774 ! secretory granule lumen +relationship: part_of GO:0042581 ! specific granule +created_by: bf +creation_date: 2010-10-05T01:33:53Z + +[Term] +id: GO:0035581 +name: sequestering of extracellular ligand from receptor +namespace: biological_process +def: "The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor." [GOC:BHF, GOC:signaling] +comment: Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex. +synonym: "extracellular sequestering of receptor ligand" EXACT [GOC:bf] +synonym: "negative regulation of protein bioavailability" RELATED [GOC:BHF] +is_a: GO:1900116 ! extracellular negative regulation of signal transduction +created_by: bf +creation_date: 2010-10-12T03:12:11Z + +[Term] +id: GO:0035582 +name: sequestering of BMP in extracellular matrix +namespace: biological_process +def: "Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins." [GOC:BHF, PMID:20855508] +comment: Confining BMP in the extracellular matrix may be achieved by binding BMP directly, or by binding to members of a BMP-containing complex. +synonym: "BMP sequestration in the ECM" EXACT [PMID:20855508] +synonym: "negative regulation of BMP signaling pathway by extracellular sequestering of BMP" EXACT [GOC:bf] +synonym: "negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP" EXACT [GOC:mah] +synonym: "negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein" EXACT [] +is_a: GO:0030514 ! negative regulation of BMP signaling pathway +is_a: GO:0035581 ! sequestering of extracellular ligand from receptor +is_a: GO:0071694 ! maintenance of protein location in extracellular region +created_by: bf +creation_date: 2010-10-12T03:12:45Z + +[Term] +id: GO:0035583 +name: sequestering of TGFbeta in extracellular matrix +namespace: biological_process +def: "Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins." [GOC:bf, GOC:BHF, GOC:signaling, PMID:12482908, PMID:20855508] +synonym: "negative regulation of transforming growth factor beta receptor signaling pathway by extracellular matrix sequestering of TGFbeta" EXACT [GOC:bf] +synonym: "negative regulation of transforming growth factor beta receptor signalling pathway by extracellular matrix sequestering of TGFbeta" EXACT [GOC:mah] +synonym: "sequestering of TGFbeta large latency complex in extracellular matrix" EXACT [PMID:12482908] +synonym: "sequestering of TGFbeta LLC in extracellular matrix" EXACT [PMID:12482908] +is_a: GO:0030512 ! negative regulation of transforming growth factor beta receptor signaling pathway +is_a: GO:0035581 ! sequestering of extracellular ligand from receptor +is_a: GO:0071694 ! maintenance of protein location in extracellular region +created_by: bf +creation_date: 2010-10-12T03:13:29Z + +[Term] +id: GO:0035584 +name: calcium-mediated signaling using intracellular calcium source +namespace: biological_process +def: "A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response." [GOC:bf, GOC:BHF, PMID:20192754] +synonym: "calcium signaling using intracellular calcium source" EXACT [] +synonym: "calcium signalling using intracellular calcium source" EXACT [] +synonym: "calcium-mediated signalling using intracellular calcium source" EXACT [] +is_a: GO:0019722 ! calcium-mediated signaling +created_by: bf +creation_date: 2010-10-18T11:01:08Z + +[Term] +id: GO:0035585 +name: calcium-mediated signaling using extracellular calcium source +namespace: biological_process +def: "A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response." [GOC:bf, GOC:BHF, PMID:20192754] +synonym: "calcium signaling using extracellular calcium source" EXACT [] +synonym: "calcium signalling using extracellular calcium source" EXACT [] +synonym: "calcium-mediated signalling using extracellular calcium source" EXACT [] +synonym: "extracellular calcium influx" NARROW [GOC:BHF] +is_a: GO:0019722 ! calcium-mediated signaling +created_by: bf +creation_date: 2010-10-18T11:04:27Z + +[Term] +id: GO:0035588 +name: G protein-coupled purinergic receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:BHF, PMID:9755289] +synonym: "G-protein coupled purinergic receptor signaling pathway" EXACT [] +synonym: "G-protein coupled purinergic receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0035590 ! purinergic nucleotide receptor signaling pathway +created_by: bf +creation_date: 2010-10-22T11:11:53Z + +[Term] +id: GO:0035589 +name: G protein-coupled purinergic nucleotide receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:BHF, PMID:9755289] +synonym: "G-protein coupled purinergic nucleotide receptor signaling pathway" EXACT [] +synonym: "G-protein coupled purinergic nucleotide receptor signalling pathway" EXACT [GOC:mah] +synonym: "P2Y receptor signaling pathway" EXACT [PMID:9755289] +is_a: GO:0035590 ! purinergic nucleotide receptor signaling pathway +created_by: bf +creation_date: 2010-10-22T11:18:59Z + +[Term] +id: GO:0035590 +name: purinergic nucleotide receptor signaling pathway +namespace: biological_process +alt_id: GO:0035587 +def: "The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity." [GOC:BHF, PMID:9755289] +synonym: "P2 receptor signaling pathway" RELATED [PMID:9755289] +synonym: "purinergic nucleotide receptor signalling pathway" EXACT [GOC:mah] +synonym: "purinergic receptor signaling pathway" RELATED [] +synonym: "purinergic receptor signalling pathway" RELATED [GOC:mah] +synonym: "purinoceptor signaling pathway" RELATED [PMID:9755289] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2010-10-22T11:09:40Z + +[Term] +id: GO:0035591 +name: signaling adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity." [GOC:bf, PMID:19104498] +comment: A signaling adaptor can bring together both protein and non-protein molecules within a signaling pathway. Scaffold proteins act in at least four ways: tethering signaling components, localizing these components to specific areas of the cell, regulating signal transduction by coordinating positive and negative feedback signals, and insulating correct signaling proteins from competing proteins (PMID:19104498). +synonym: "signaling scaffold activity" RELATED [] +synonym: "signalling adaptor activity" EXACT [GOC:mah] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19050 xsd:anyURI +created_by: bf +creation_date: 2010-11-05T11:22:01Z + +[Term] +id: GO:0035592 +name: establishment of protein localization to extracellular region +namespace: biological_process +def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF] +synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah] +synonym: "establishment of protein localization in extracellular region" EXACT [] +is_a: GO:0045184 ! establishment of protein localization +is_a: GO:0071692 ! protein localization to extracellular region +created_by: bf +creation_date: 2010-11-09T10:25:08Z + +[Term] +id: GO:0035593 +name: positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region." [GOC:BHF, PMID:19906850] +synonym: "positive regulation of Wnt diffusion" NARROW [PMID:19906850] +synonym: "positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localisation in extracellular region" EXACT [GOC:mah] +synonym: "positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization in extracellular region" EXACT [] +synonym: "positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization to extracellular region" EXACT [] +synonym: "positive regulation of Wnt receptor signalling pathway by establishment of Wnt protein localization in extracellular region" EXACT [GOC:mah] +synonym: "positive regulation of Wnt signaling range" RELATED [PMID:19906850] +synonym: "positive regulation of Wnt-activated signaling pathway by establishment of Wnt protein localization to extracellular region" EXACT [GOC:signaling] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:0035592 ! establishment of protein localization to extracellular region +created_by: bf +creation_date: 2010-11-09T10:29:44Z + +[Term] +id: GO:0035594 +name: ganglioside binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues." [GOC:yaf] +is_a: GO:0043208 ! glycosphingolipid binding +is_a: GO:0097001 ! ceramide binding +created_by: bf +creation_date: 2010-11-11T02:11:38Z + +[Term] +id: GO:0035595 +name: N-acetylglucosaminylinositol deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol." [EC:3.5.1.103, GOC:rs] +synonym: "1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity" EXACT [EC:3.5.1.103] +synonym: "1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity" EXACT [EC:3.5.1.103] +synonym: "GlcNAc-Ins deacetylase activity" EXACT [GOC:rs] +synonym: "N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity" EXACT [EC:3.5.1.103] +xref: EC:3.5.1.103 +xref: KEGG_REACTION:R09651 +xref: MetaCyc:RXN1G-2 +xref: RHEA:26180 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity +created_by: bf +creation_date: 2010-11-11T02:12:48Z + +[Term] +id: GO:0035596 +name: methylthiotransferase activity +namespace: molecular_function +def: "Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor." [GOC:jh2, PMID:20472640] +synonym: "MTTase" EXACT [PMID:20472640] +is_a: GO:0050497 ! transferase activity, transferring alkylthio groups +created_by: bf +creation_date: 2010-11-12T01:24:38Z + +[Term] +id: GO:0035597 +name: N6-isopentenyladenosine methylthiotransferase activity +namespace: molecular_function +def: "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A)." [PMID:20472640] +synonym: "i6A methylthiotransferase activity" EXACT [PMID:20472640] +is_a: GO:0035596 ! methylthiotransferase activity +relationship: part_of GO:0035600 ! tRNA methylthiolation +created_by: bf +creation_date: 2010-11-12T01:26:58Z + +[Term] +id: GO:0035598 +name: N6-threonylcarbomyladenosine methylthiotransferase activity +namespace: molecular_function +def: "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A)." [PMID:20472640, PMID:20584901] +synonym: "t6A methylthiotransferase activity" EXACT [PMID:20472640] +xref: Reactome:R-HSA-6786571 "CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37" +is_a: GO:0035596 ! methylthiotransferase activity +relationship: part_of GO:0035600 ! tRNA methylthiolation +created_by: bf +creation_date: 2010-11-12T01:28:32Z + +[Term] +id: GO:0035599 +name: aspartic acid methylthiotransferase activity +namespace: molecular_function +def: "Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid." [PMID:18252828, PMID:8844851, RESID:AA0232] +comment: Note that peptidyl-L-beta-methylthioaspartic acid is typical of bacterial ribosomal protein S12. +xref: RESID:AA0232 +is_a: GO:0035596 ! methylthiotransferase activity +relationship: part_of GO:0018339 ! peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid +created_by: bf +creation_date: 2010-11-12T01:31:23Z + +[Term] +id: GO:0035600 +name: tRNA methylthiolation +namespace: biological_process +def: "The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule." [PMID:20472640] +is_a: GO:0006400 ! tRNA modification +created_by: bf +creation_date: 2010-11-12T01:34:02Z + +[Term] +id: GO:0035601 +name: protein deacylation +namespace: biological_process +def: "The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid." [GOC:se, PMID:12080046] +synonym: "protein amino acid deacylation" EXACT [GOC:se] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0098732 ! macromolecule deacylation +created_by: bf +creation_date: 2010-11-15T11:06:15Z + +[Term] +id: GO:0035602 +name: fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow." [GOC:mtg_apoptosis, GOC:yaf] +synonym: "FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow" EXACT [GOC:bf] +synonym: "FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow" EXACT [GOC:bf] +synonym: "fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow" NARROW [] +synonym: "fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow" EXACT [] +synonym: "fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0071866 ! negative regulation of apoptotic process in bone marrow cell +relationship: part_of GO:0071866 ! negative regulation of apoptotic process in bone marrow cell +created_by: bf +creation_date: 2010-11-15T11:09:20Z + +[Term] +id: GO:0035603 +name: fibroblast growth factor receptor signaling pathway involved in hemopoiesis +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis." [GOC:yaf] +synonym: "FGF receptor signaling pathway involved in hematopoiesis" EXACT [GOC:bf] +synonym: "FGFR signaling pathway involved in hematopoiesis" EXACT [GOC:bf] +synonym: "fibroblast growth factor receptor signaling pathway involved in hematopoiesis" EXACT [GOC:yaf] +synonym: "fibroblast growth factor receptor signalling pathway involved in hemopoiesis" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0030097 ! hemopoiesis +relationship: part_of GO:0030097 ! hemopoiesis +created_by: bf +creation_date: 2010-11-15T11:09:46Z + +[Term] +id: GO:0035604 +name: fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow." [GOC:yaf] +synonym: "FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow" EXACT [GOC:bf] +synonym: "FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow" EXACT [GOC:bf] +synonym: "fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0071864 ! positive regulation of cell proliferation in bone marrow +relationship: part_of GO:0071864 ! positive regulation of cell proliferation in bone marrow +created_by: bf +creation_date: 2010-11-15T11:10:14Z + +[Term] +id: GO:0035605 +name: peptidyl-cysteine S-nitrosylase activity +namespace: molecular_function +def: "Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein." [EC:2.6.99.-, GOC:sp, PMID:20972425, PMID:20972426] +comment: This term should not be used to annotate the nitrosylating action of nitric oxide synthase (NOS) if the nitroso group is synthesized directly on the substrate. +synonym: "protein nitrosylase activity" RELATED [GOC:sp] +synonym: "S-nitrosylase activity" EXACT [PMID:20972426] +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0018119 ! peptidyl-cysteine S-nitrosylation +created_by: bf +creation_date: 2010-11-16T09:49:26Z + +[Term] +id: GO:0035606 +name: peptidyl-cysteine S-trans-nitrosylation +namespace: biological_process +def: "Transfer of a nitric oxide (NO) group from one cysteine residue to another." [PMID:19854201, PMID:20972425, PMID:20972426] +synonym: "cysteine to cysteine nitrosylation" EXACT [PMID:20972426] +synonym: "cysteine-to-cysteine transnitrosylation" EXACT [PMID:20972426] +synonym: "protein-to-protein transnitrosylation" BROAD [PMID:20972426] +synonym: "S-transnitrosylation" EXACT [PMID:20972426] +is_a: GO:0018119 ! peptidyl-cysteine S-nitrosylation +created_by: bf +creation_date: 2010-11-16T09:54:46Z + +[Term] +id: GO:0035607 +name: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state." [GOC:yaf] +synonym: "FGF receptor signaling pathway involved in orbitofrontal cortex development" EXACT [GOC:bf] +synonym: "FGFR signaling pathway involved in orbitofrontal cortex development" EXACT [GOC:bf] +synonym: "fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development" EXACT [GOC:bf] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0021769 ! orbitofrontal cortex development +relationship: part_of GO:0021769 ! orbitofrontal cortex development +created_by: bf +creation_date: 2010-11-16T11:30:19Z + +[Term] +id: GO:0035608 +name: protein deglutamylation +namespace: biological_process +def: "The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation." [GOC:sp, PMID:21074048] +synonym: "protein amino acid deglutamylation" EXACT [GOC:bf] +is_a: GO:0018200 ! peptidyl-glutamic acid modification +created_by: bf +creation_date: 2010-11-18T01:04:38Z + +[Term] +id: GO:0035609 +name: C-terminal protein deglutamylation +namespace: biological_process +def: "The removal of a C-terminal, gene-encoded glutamate residue from a protein." [GOC:sp, PMID:21074048] +synonym: "protein primary sequence deglutamylation" EXACT [PMID:21074048] +is_a: GO:0018410 ! C-terminal protein amino acid modification +is_a: GO:0035608 ! protein deglutamylation +created_by: bf +creation_date: 2010-11-18T01:06:00Z + +[Term] +id: GO:0035610 +name: protein side chain deglutamylation +namespace: biological_process +def: "The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation." [GOC:sp, PMID:21074048] +synonym: "removal of posttranslational polyglutamylation" EXACT [PMID:21074048] +synonym: "shortening of glutamate side chain" RELATED [PMID:21074048] +is_a: GO:0035608 ! protein deglutamylation +created_by: bf +creation_date: 2010-11-18T01:09:03Z + +[Term] +id: GO:0035611 +name: protein branching point deglutamylation +namespace: biological_process +def: "The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue." [GOC:sp, PMID:21074048] +is_a: GO:0035608 ! protein deglutamylation +created_by: bf +creation_date: 2010-11-18T01:11:21Z + +[Term] +id: GO:0035612 +name: AP-2 adaptor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)." [GOC:BHF, PMID:12221107, PMID:15728179, PMID:21097499] +synonym: "AP-2 clathrin adaptor complex binding" RELATED [GOC:bf] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2010-11-25T03:51:17Z + +[Term] +id: GO:0035613 +name: RNA stem-loop binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop." [GOC:sart, PMID:16568238, PMID:20455544] +synonym: "RNA hairpin binding" EXACT [PMID:16568238] +synonym: "RNA hairpin loop binding" EXACT [PMID:16568238] +is_a: GO:0003723 ! RNA binding +created_by: bf +creation_date: 2010-11-26T10:41:49Z + +[Term] +id: GO:0035614 +name: snRNA stem-loop binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop." [GOC:sart, PMID:16568238, PMID:20455544] +synonym: "small nuclear RNA stem-loop binding" EXACT [] +synonym: "snRNA hairpin binding" EXACT [PMID:16568238] +synonym: "snRNA hairpin loop binding" EXACT [PMID:16568238] +is_a: GO:0017069 ! snRNA binding +is_a: GO:0035613 ! RNA stem-loop binding +created_by: bf +creation_date: 2010-11-26T10:43:17Z + +[Term] +id: GO:0035615 +name: clathrin adaptor activity +namespace: molecular_function +def: "Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles." [GOC:BHF, PMID:15728179] +synonym: "clathrin-associated adaptor activity" EXACT [PMID:15728179] +is_a: GO:0030276 ! clathrin binding +is_a: GO:0140312 ! cargo adaptor activity +created_by: bf +creation_date: 2010-12-01T11:17:57Z + +[Term] +id: GO:0035616 +name: histone H2B conserved C-terminal lysine deubiquitination +namespace: biological_process +def: "A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals." [GOC:bf, GOC:vw, PMID:15657442] +synonym: "budding yeast H2B K123 deubiquitination" NARROW [GOC:vw] +synonym: "fission yeast H2B K119 deubiquitination" NARROW [GOC:vw] +synonym: "mammalian H2B K120 deubiquitination" NARROW [GOC:vw] +is_a: GO:0016578 ! histone deubiquitination +created_by: bf +creation_date: 2010-12-03T10:36:44Z + +[Term] +id: GO:0035617 +name: stress granule disassembly +namespace: biological_process +def: "The disaggregation of a stress granule into its constituent protein and RNA parts." [GOC:BHF, PMID:19825938] +synonym: "SG disassembly" EXACT [PMID:19825938] +is_a: GO:0032988 ! ribonucleoprotein complex disassembly +is_a: GO:1903008 ! organelle disassembly +created_by: bf +creation_date: 2010-12-03T10:38:57Z + +[Term] +id: GO:0035618 +name: root hair +namespace: cellular_component +def: "A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall." [http://www.jstor.org/stable/4354264, PO:0000256] +comment: This term is a child of 'cell projection' and not 'cell hair' to distinguish it from animal cell hairs, which are morphologically distinct. +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: bf +creation_date: 2010-12-03T01:42:40Z + +[Term] +id: GO:0035619 +name: root hair tip +namespace: cellular_component +def: "The tip portion of an outgrowth of a root epidermal cell." [PMID:16567499] +synonym: "root hair cell tip" EXACT [] +is_a: GO:0051286 ! cell tip +intersection_of: GO:0051286 ! cell tip +intersection_of: part_of GO:0035618 ! root hair +relationship: part_of GO:0035618 ! root hair +created_by: bf +creation_date: 2010-12-03T01:43:55Z + +[Term] +id: GO:0035621 +name: ER to Golgi ceramide transport +namespace: biological_process +def: "The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:sart, PMID:14685229] +synonym: "endoplasmic reticulum to Golgi ceramide transport" EXACT [GOC:bf] +synonym: "ER to Golgi ceramide translocation" EXACT [PMID:14685229] +synonym: "non-vesicular ceramide trafficking" EXACT [PMID:14685229] +is_a: GO:0032365 ! intracellular lipid transport +is_a: GO:0035627 ! ceramide transport +created_by: bf +creation_date: 2010-12-08T12:36:35Z + +[Term] +id: GO:0035622 +name: intrahepatic bile duct development +namespace: biological_process +def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624] +synonym: "IHBD development" EXACT [PMID:20614624] +synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624] +is_a: GO:0061009 ! common bile duct development +relationship: part_of GO:0001889 ! liver development +created_by: bf +creation_date: 2010-12-08T04:10:50Z + +[Term] +id: GO:0035623 +name: renal glucose absorption +namespace: biological_process +def: "A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:yaf, PMID:11269503] +synonym: "glucose reabsorption" EXACT [GOC:yaf] +synonym: "nephron glucose absorption" EXACT [GOC:yaf] +is_a: GO:0070293 ! renal absorption +is_a: GO:1904659 ! glucose transmembrane transport +created_by: bf +creation_date: 2010-12-08T04:14:23Z + +[Term] +id: GO:0035624 +name: receptor transactivation +namespace: biological_process +def: "The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer." [GOC:al, GOC:bf, GOC:BHF, PMID:16870826, PMID:21063387] +is_a: GO:2000273 ! positive regulation of signaling receptor activity +created_by: bf +creation_date: 2010-12-08T04:18:18Z + +[Term] +id: GO:0035625 +name: obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway +namespace: biological_process +def: "OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways." [GOC:bf, GOC:BHF, PMID:10622253, PMID:17655843] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "EGFR transactivation by GPCR" EXACT [GOC:bf] +synonym: "EGFR transactivation upon GPCR stimulation" EXACT [PMID:10622253] +synonym: "epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway" EXACT [GOC:bf, GOC:signaling] +synonym: "epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signalling pathway" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15823 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2010-12-08T04:19:12Z + +[Term] +id: GO:0035626 +name: juvenile hormone mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity." [GOC:bf, GOC:sart] +synonym: "juvenile hormone mediated signalling pathway" EXACT [GOC:bf] +synonym: "juvenile hormone-mediated signaling pathway" EXACT [GOC:bf] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0030522 ! intracellular receptor signaling pathway +created_by: bf +creation_date: 2010-12-08T04:45:25Z + +[Term] +id: GO:0035627 +name: ceramide transport +namespace: biological_process +def: "The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid." [GOC:bf, GOC:sart] +is_a: GO:0006869 ! lipid transport +is_a: GO:0042886 ! amide transport +created_by: bf +creation_date: 2010-12-10T10:02:16Z + +[Term] +id: GO:0035628 +name: cystic duct development +namespace: biological_process +def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct." [PMID:20614624] +is_a: GO:0061009 ! common bile duct development +created_by: bf +creation_date: 2010-12-10T01:24:28Z + +[Term] +id: GO:0035629 +name: N-terminal protein amino acid N-linked glycosylation +namespace: biological_process +def: "Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein." [GOC:bf, GOC:pr] +comment: Note that the only known alpha amino glycosylation is on an asparagine; see UniProtKB:P58522. However, this feature is not differentiated from normal N-glycosylation of asparagine. +is_a: GO:0006487 ! protein N-linked glycosylation +is_a: GO:0031365 ! N-terminal protein amino acid modification +created_by: bf +creation_date: 2010-12-17T10:45:48Z + +[Term] +id: GO:0035630 +name: bone mineralization involved in bone maturation +namespace: biological_process +def: "The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state." [GOC:bf, GOC:BHF] +comment: Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'. +is_a: GO:0030282 ! bone mineralization +intersection_of: GO:0030282 ! bone mineralization +intersection_of: part_of GO:0043931 ! ossification involved in bone maturation +relationship: part_of GO:0043931 ! ossification involved in bone maturation +created_by: bf +creation_date: 2010-12-20T01:57:31Z + +[Term] +id: GO:0035631 +name: CD40 receptor complex +namespace: cellular_component +def: "A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules." [GOC:BHF, PMID:20614026, PMID:9221764] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bf +creation_date: 2010-12-21T10:35:05Z + +[Term] +id: GO:0035632 +name: mitochondrial prohibitin complex +namespace: cellular_component +def: "A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death." [GOC:kmv, PMID:12237468, PMID:21164222] +synonym: "mitochondrial inner membrane prohibitin complex" EXACT [GOC:bf] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +created_by: bf +creation_date: 2010-12-21T10:38:59Z + +[Term] +id: GO:0035633 +name: maintenance of blood-brain barrier +namespace: biological_process +def: "Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation." [GOC:aruk, GOC:bc, GOC:bf, GOC:sl, PMID:20080302, PMID:30280653] +comment: Homeostasis and maintenance processes are regulatory processes, therefore, regulation child terms, such as: regulation of maintenance of blood-brain barrier, should not exist for these terms. \nInstead, for capturing regulation at the blood-brain barrier, consider using the part_of child term: regulation of blood-brain barrier permeability. +synonym: "maintenance of BBB" EXACT [] +synonym: "maintenance of blood/brain barrier" EXACT [] +is_a: GO:0001894 ! tissue homeostasis +created_by: bf +creation_date: 2011-01-07T10:33:11Z + +[Term] +id: GO:0035634 +name: response to stilbenoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones." [GOC:yaf, Wikipedia:Stilbenoid] +subset: goslim_chembl +is_a: GO:0014070 ! response to organic cyclic compound +created_by: bf +creation_date: 2011-01-12T10:37:33Z + +[Term] +id: GO:0035635 +name: entry of bacterium into host cell +namespace: biological_process +def: "The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, PMID:21187937] +synonym: "bacterial entry into host cell" EXACT [GOC:bf] +synonym: "invasion of bacteria into host cell" EXACT [GOC:bf] +is_a: GO:0044409 ! entry into host +created_by: bf +creation_date: 2011-01-13T02:26:54Z + +[Term] +id: GO:0035636 +name: obsolete multi-organism signaling +namespace: biological_process +def: "OBSOLETE. The transfer of information between living organisms." [GOC:go_curators] +comment: This term was obsoleted because it was a grouping term but had no subclasses. +synonym: "multi-organism signalling" EXACT [GOC:bf] +synonym: "pheromone signaling" NARROW [GOC:bf] +synonym: "signaling between organisms" EXACT [GOC:bf] +synonym: "signaling with other organism" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2011-01-14T10:11:25Z + +[Term] +id: GO:0035637 +name: multicellular organismal signaling +namespace: biological_process +def: "The transfer of information occurring at the level of a multicellular organism." [GOC:go_curators] +synonym: "multicellular organismal signalling" EXACT [GOC:bf] +is_a: GO:0023052 ! signaling +is_a: GO:0032501 ! multicellular organismal process +created_by: bf +creation_date: 2011-01-14T10:13:50Z + +[Term] +id: GO:0035639 +name: purine ribonucleoside triphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar." [GOC:BHF, GOC:ebc, ISBN:0198506732] +synonym: "purine NTP binding" BROAD [GOC:ebc] +is_a: GO:0043168 ! anion binding +is_a: GO:1901265 ! nucleoside phosphate binding +created_by: bf +creation_date: 2011-01-14T02:46:42Z + +[Term] +id: GO:0035640 +name: exploration behavior +namespace: biological_process +def: "The specific behavior of an organism in response to a novel environment or stimulus." [GOC:BHF, GOC:pr, PMID:11682103, PMID:9767169] +comment: For changes in locomotory behavior upon introduction to a novel environment, consider instead the child term: locomotory exploration behavior ; GO:0035641. +synonym: "exploration behaviour" EXACT [GOC:bf] +synonym: "exploratory behavior" EXACT [PMID:20869398] +synonym: "exploratory behaviour" EXACT [PMID:11682103] +synonym: "open-field behavior" NARROW [PMID:11682103] +is_a: GO:0007610 ! behavior +created_by: bf +creation_date: 2011-01-19T10:35:45Z + +[Term] +id: GO:0035641 +name: locomotory exploration behavior +namespace: biological_process +def: "The specific movement from place to place of an organism in response to a novel environment." [GOC:sart, PMID:17151232] +is_a: GO:0007626 ! locomotory behavior +is_a: GO:0035640 ! exploration behavior +created_by: bf +creation_date: 2011-01-19T10:40:04Z + +[Term] +id: GO:0035642 +name: histone methyltransferase activity (H3-R17 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3." [GOC:sp, PMID:11341840] +synonym: "histone methylase activity (H3-R17 specific)" EXACT [GOC:bf] +synonym: "histone-arginine N-methyltransferase activity (H3-R17 specific)" EXACT [GOC:bf] +is_a: GO:0008469 ! histone-arginine N-methyltransferase activity +relationship: part_of GO:0034971 ! histone H3-R17 methylation +created_by: bf +creation_date: 2011-01-19T10:41:43Z + +[Term] +id: GO:0035643 +name: L-DOPA receptor activity +namespace: molecular_function +def: "Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine." [PMID:18828673, Wikipedia:L-DOPA] +synonym: "L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity" EXACT [] +synonym: "L-dopa receptor activity" EXACT [] +is_a: GO:0008188 ! neuropeptide receptor activity +relationship: has_part GO:0072544 ! L-DOPA binding +created_by: bf +creation_date: 2011-01-20T10:34:23Z + +[Term] +id: GO:0035644 +name: phosphoanandamide dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from a phosphorylated anandamide." [GOC:BHF, PMID:16938887] +is_a: GO:0016311 ! dephosphorylation +created_by: bf +creation_date: 2011-01-21T02:14:04Z + +[Term] +id: GO:0035645 +name: enteric smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF] +synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504] +is_a: GO:0051145 ! smooth muscle cell differentiation +relationship: part_of GO:0048565 ! digestive tract development +created_by: bf +creation_date: 2011-01-21T02:58:58Z + +[Term] +id: GO:0035646 +name: endosome to melanosome transport +namespace: biological_process +def: "The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle." [PMID:16162817] +is_a: GO:0043485 ! endosome to pigment granule transport +created_by: bf +creation_date: 2011-01-24T01:30:07Z + +[Term] +id: GO:0035647 +name: 3-oxo-delta(4,5)-steroid 5-beta-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+)." [GOC:kad, MetaCyc:RXN-9726, PMID:19166903] +synonym: "3-oxo-delta4,5-steroid 5beta-reductase" EXACT [GOC:kad] +is_a: GO:0035671 ! enone reductase activity +created_by: bf +creation_date: 2011-01-24T01:31:30Z + +[Term] +id: GO:0035648 +name: circadian mating behavior +namespace: biological_process +def: "The fluctuation in mating behavior that occurs over an approximately 24 hour cycle." [GOC:bf, GOC:dos, PMID:11470898, PMID:17276917] +synonym: "circadian mating behaviour" EXACT [GOC:bf] +synonym: "circadian mating rhythm" EXACT [GOC:dos] +is_a: GO:0007617 ! mating behavior +is_a: GO:0048512 ! circadian behavior +created_by: bf +creation_date: 2011-01-25T10:20:05Z + +[Term] +id: GO:0035649 +name: Nrd1 complex +namespace: cellular_component +def: "A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p." [GOC:jh, PMID:10655211, PMID:16427013, PMID:21084293] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2011-01-25T10:23:25Z + +[Term] +id: GO:0035650 +name: AP-1 adaptor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C)." [PMID:21097499] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2011-01-25T10:58:52Z + +[Term] +id: GO:0035651 +name: AP-3 adaptor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B)." [PMID:21097499] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2011-01-25T10:59:36Z + +[Term] +id: GO:0035652 +name: clathrin-coated vesicle cargo loading +namespace: biological_process +def: "Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle." [GOC:lb, PMID:16162817] +synonym: "cargo loading into clathrin-coated vesicle" EXACT [] +is_a: GO:0035459 ! vesicle cargo loading +created_by: bf +creation_date: 2011-01-25T11:00:43Z + +[Term] +id: GO:0035653 +name: clathrin-coated vesicle cargo loading, AP-1-mediated +namespace: biological_process +def: "Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking." [GOC:lb, PMID:12802059, PMID:16162817] +synonym: "cargo loading into clathrin-coated vesicle, AP-1-mediated" EXACT [] +is_a: GO:0035652 ! clathrin-coated vesicle cargo loading +created_by: bf +creation_date: 2011-01-25T11:01:38Z + +[Term] +id: GO:0035654 +name: clathrin-coated vesicle cargo loading, AP-3-mediated +namespace: biological_process +def: "Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle." [GOC:lb, PMID:12802059, PMID:16162817] +synonym: "cargo loading into clathrin-coated vesicle, AP-3-mediated" EXACT [] +is_a: GO:0035652 ! clathrin-coated vesicle cargo loading +created_by: bf +creation_date: 2011-01-25T11:02:30Z + +[Term] +id: GO:0035655 +name: interleukin-18-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:BHF, GOC:signaling] +synonym: "interleukin-18-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071351 ! cellular response to interleukin-18 +created_by: bf +creation_date: 2011-01-26T09:55:57Z + +[Term] +id: GO:0035656 +name: obsolete kinesin-associated melanosomal adaptor activity +namespace: molecular_function +def: "OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes." [PMID:19841138] +comment: This term was obsoleted because it represents the function of a specific protein. +synonym: "kinesin-melanosome adaptor activity" EXACT [GOC:bf] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17668 xsd:anyURI +is_obsolete: true +consider: GO:0008093 +consider: GO:0030674 +created_by: bf +creation_date: 2011-01-27T01:32:51Z + +[Term] +id: GO:0035657 +name: eRF1 methyltransferase complex +namespace: cellular_component +def: "A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p." [GOC:rb, PMID:17008308, PMID:20400505] +synonym: "eRF1 MTase complex" EXACT [PMID:17008308] +is_a: GO:0034708 ! methyltransferase complex +created_by: bf +creation_date: 2011-01-28T11:29:40Z + +[Term] +id: GO:0035658 +name: Mon1-Ccz1 complex +namespace: cellular_component +def: "A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p." [GOC:rb, PMID:20797862] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005770 ! late endosome +created_by: bf +creation_date: 2011-01-28T11:31:20Z + +[Term] +id: GO:0035659 +name: Wnt signaling pathway involved in wound healing, spreading of epidermal cells +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis." [GOC:BHF] +synonym: "Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells" EXACT [] +synonym: "Wnt receptor signalling pathway involved in wound healing, spreading of epidermal cells" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in wound healing, spreading of epidermal cells" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0035313 ! wound healing, spreading of epidermal cells +relationship: part_of GO:0035313 ! wound healing, spreading of epidermal cells +created_by: bf +creation_date: 2011-01-28T11:34:02Z + +[Term] +id: GO:0035660 +name: MyD88-dependent toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18304834, PMID:20385024] +synonym: "MyD88-dependent TLR4 signaling pathway" EXACT [GOC:bf] +synonym: "MyD88-dependent toll-like receptor 4 signalling pathway" EXACT [GOC:bf] +is_a: GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway +is_a: GO:0034142 ! toll-like receptor 4 signaling pathway +created_by: bf +creation_date: 2011-02-01T10:10:04Z + +[Term] +id: GO:0035661 +name: MyD88-dependent toll-like receptor 2 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response." [GOC:BHF, PMID:20385024] +synonym: "MyD88-dependent TLR2 signaling pathway" EXACT [GOC:bf] +synonym: "MyD88-dependent toll-like receptor 2 signalling pathway" EXACT [GOC:bf] +is_a: GO:0002755 ! MyD88-dependent toll-like receptor signaling pathway +is_a: GO:0034134 ! toll-like receptor 2 signaling pathway +created_by: bf +creation_date: 2011-02-01T10:11:01Z + +[Term] +id: GO:0035662 +name: Toll-like receptor 4 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18304834] +synonym: "TLR4 binding" EXACT [GOC:bf] +is_a: GO:0035325 ! Toll-like receptor binding +created_by: bf +creation_date: 2011-02-01T10:20:59Z + +[Term] +id: GO:0035663 +name: Toll-like receptor 2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response." [GOC:BHF] +synonym: "TLR2 binding" EXACT [GOC:bf] +is_a: GO:0035325 ! Toll-like receptor binding +created_by: bf +creation_date: 2011-02-01T10:21:51Z + +[Term] +id: GO:0035664 +name: TIRAP-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:11526399, PMID:11544529, PMID:12447442] +synonym: "MAL-dependent toll-like receptor signaling pathway" EXACT [PMID:11544529] +synonym: "MyD88 adapter-like dependent toll-like receptor signaling pathway" EXACT [PMID:11544529] +synonym: "TIRAP-dependent TLR signaling pathway" EXACT [GOC:bf] +synonym: "TIRAP-dependent toll-like receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0002224 ! toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:31:37Z + +[Term] +id: GO:0035665 +name: TIRAP-dependent toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:12447441] +synonym: "MAL-dependent toll-like receptor 4 signaling pathway" EXACT [PMID:11544529] +synonym: "MyD88 adapter-like dependent toll-like receptor 4 signaling pathway" EXACT [GOC:11544529] +synonym: "TIRAP-dependent TLR4 signaling pathway" EXACT [GOC:bf] +synonym: "TIRAP-dependent toll-like receptor 4 signalling pathway" EXACT [GOC:bf] +is_a: GO:0034142 ! toll-like receptor 4 signaling pathway +is_a: GO:0035664 ! TIRAP-dependent toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:33:48Z + +[Term] +id: GO:0035666 +name: TRIF-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:12855817] +synonym: "Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway" EXACT [PMID:12855817] +synonym: "TRIF-dependent TLR signaling pathway" EXACT [GOC:bf] +synonym: "TRIF-dependent toll-like receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0002756 ! MyD88-independent toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:35:35Z + +[Term] +id: GO:0035667 +name: TRIF-dependent toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:18641322, PMID:20511708] +synonym: "Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway" EXACT [PMID:12855817] +synonym: "TRIF-dependent TLR4 signaling pathway" EXACT [GOC:bf] +synonym: "TRIF-dependent toll-like receptor 4 signalling pathway" EXACT [GOC:bf] +is_a: GO:0034142 ! toll-like receptor 4 signaling pathway +is_a: GO:0035666 ! TRIF-dependent toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:37:25Z + +[Term] +id: GO:0035668 +name: TRAM-dependent toll-like receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:BHF, PMID:14556004] +synonym: "TRAM-dependent TLR signaling pathway" EXACT [GOC:bf] +synonym: "TRAM-dependent toll-like receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0002756 ! MyD88-independent toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:39:34Z + +[Term] +id: GO:0035669 +name: TRAM-dependent toll-like receptor 4 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response." [GOC:BHF, PMID:14556004, PMID:18297073] +synonym: "TRAM-dependent TLR4 signaling pathway" EXACT [GOC:bf] +synonym: "TRAM-dependent toll-like receptor 4 signalling pathway" EXACT [GOC:bf] +is_a: GO:0034142 ! toll-like receptor 4 signaling pathway +is_a: GO:0035668 ! TRAM-dependent toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-01T02:41:09Z + +[Term] +id: GO:0035670 +name: plant-type ovary development +namespace: biological_process +def: "The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed." [GOC:bf, GOC:tb, ISBN:0879015322] +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0048440 ! carpel development +created_by: bf +creation_date: 2011-02-04T09:35:05Z + +[Term] +id: GO:0035671 +name: enone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+." [EC:1.3.1.-, GOC:kad, PMID:17945329, PMID:19166903] +xref: MetaCyc:RXN-12267 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2011-02-04T10:59:15Z + +[Term] +id: GO:0035672 +name: oligopeptide transmembrane transport +namespace: biological_process +def: "The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:vw, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "oligopeptide membrane transport" EXACT [] +is_a: GO:0006857 ! oligopeptide transport +is_a: GO:0055085 ! transmembrane transport +created_by: bf +creation_date: 2011-02-08T02:18:07Z + +[Term] +id: GO:0035673 +name: oligopeptide transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015198 +def: "Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:vw, ISBN:0198506732] +synonym: "oligopeptide transporter activity" RELATED [] +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0035672 ! oligopeptide transmembrane transport +created_by: bf +creation_date: 2011-02-08T02:20:14Z + +[Term] +id: GO:0035674 +name: tricarboxylic acid transmembrane transport +namespace: biological_process +def: "The process in which a tricarboxylic acid is transported across a membrane." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "tricarboxylic acid membrane transport" EXACT [] +is_a: GO:0006842 ! tricarboxylic acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: bf +creation_date: 2011-02-08T02:37:31Z + +[Term] +id: GO:0035675 +name: neuromast hair cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0000856] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0048886 ! neuromast hair cell differentiation +created_by: bf +creation_date: 2011-02-14T11:01:42Z + +[Term] +id: GO:0035676 +name: anterior lateral line neuromast hair cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [ISBN:0125296509, ISBN:0387968377] +is_a: GO:0035675 ! neuromast hair cell development +relationship: part_of GO:0048903 ! anterior lateral line neuromast hair cell differentiation +created_by: bf +creation_date: 2011-02-14T11:03:57Z + +[Term] +id: GO:0035677 +name: posterior lateral line neuromast hair cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate." [ISBN:0125296509] +is_a: GO:0035675 ! neuromast hair cell development +relationship: part_of GO:0048923 ! posterior lateral line neuromast hair cell differentiation +created_by: bf +creation_date: 2011-02-14T11:04:57Z + +[Term] +id: GO:0035678 +name: neuromast hair cell morphogenesis +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [CL:0000856] +is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation +relationship: part_of GO:0035675 ! neuromast hair cell development +created_by: bf +creation_date: 2011-02-14T11:06:15Z + +[Term] +id: GO:0035679 +name: anterior lateral line neuromast hair cell morphogenesis +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [ISBN:0125296509, ISBN:0387968377] +is_a: GO:0035678 ! neuromast hair cell morphogenesis +relationship: part_of GO:0035676 ! anterior lateral line neuromast hair cell development +created_by: bf +creation_date: 2011-02-14T11:06:54Z + +[Term] +id: GO:0035680 +name: posterior lateral line neuromast hair cell morphogenesis +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface." [ISBN:0125296509] +is_a: GO:0035678 ! neuromast hair cell morphogenesis +relationship: part_of GO:0035677 ! posterior lateral line neuromast hair cell development +created_by: bf +creation_date: 2011-02-14T11:08:14Z + +[Term] +id: GO:0035681 +name: toll-like receptor 15 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 15." [GOC:pde] +synonym: "TLR15 signaling pathway" EXACT [GOC:bf] +synonym: "toll-like receptor 15 signalling pathway" EXACT [GOC:mah] +is_a: GO:0002224 ! toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-21T02:38:47Z + +[Term] +id: GO:0035682 +name: toll-like receptor 21 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 21." [GOC:pde] +synonym: "TLR21 signaling pathway" EXACT [GOC:bf] +synonym: "toll-like receptor 21 signalling pathway" EXACT [GOC:mah] +is_a: GO:0002224 ! toll-like receptor signaling pathway +created_by: bf +creation_date: 2011-02-21T02:39:39Z + +[Term] +id: GO:0035683 +name: memory T cell extravasation +namespace: biological_process +def: "The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive." [CL:0000813, GOC:BHF] +synonym: "memory T-cell extravasation" EXACT [GOC:ebc] +is_a: GO:0072683 ! T cell extravasation +created_by: bf +creation_date: 2011-02-23T01:10:02Z + +[Term] +id: GO:0035684 +name: helper T cell extravasation +namespace: biological_process +def: "The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells." [CL:0000912, GOC:BHF] +synonym: "helper T-cell extravasation" EXACT [GOC:ebc] +synonym: "T-helper cell extravasation" EXACT [CL:0000912] +is_a: GO:0072683 ! T cell extravasation +created_by: bf +creation_date: 2011-02-23T01:11:05Z + +[Term] +id: GO:0035685 +name: helper T cell diapedesis +namespace: biological_process +def: "The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation." [CL:0000912, GOC:BHF] +synonym: "helper T-cell diapedesis" EXACT [CL:0000912] +synonym: "T-helper cell diapedesis" EXACT [CL:0000912] +is_a: GO:0050904 ! diapedesis +is_a: GO:0072678 ! T cell migration +relationship: part_of GO:0035684 ! helper T cell extravasation +created_by: bf +creation_date: 2011-02-23T01:11:52Z + +[Term] +id: GO:0035686 +name: sperm fibrous sheath +namespace: cellular_component +def: "A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat." [GOC:BHF, GOC:cilia, GOC:krc, PMID:20731842, PMID:3282552] +synonym: "flagellar fibrous sheath" EXACT [] +synonym: "flagellum fibrous sheath" EXACT [GOC:bf] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: bf +creation_date: 2011-02-24T09:10:58Z + +[Term] +id: GO:0035687 +name: T-helper 1 cell extravasation +namespace: biological_process +def: "The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:BHF] +synonym: "Th1 cell extravasation" EXACT [CL:0000545] +is_a: GO:0035684 ! helper T cell extravasation +is_a: GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-02-24T10:10:00Z + +[Term] +id: GO:0035688 +name: T-helper 1 cell diapedesis +namespace: biological_process +def: "The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:BHF, PMID:10477596] +synonym: "Th1 cell diapedesis" EXACT [CL:0000545] +is_a: GO:0035685 ! helper T cell diapedesis +relationship: part_of GO:0035687 ! T-helper 1 cell extravasation +created_by: bf +creation_date: 2011-02-24T10:12:11Z + +[Term] +id: GO:0035689 +name: chemokine (C-C motif) ligand 5 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, PMID:18337562] +synonym: "CCL5-mediated signaling pathway" EXACT [PMID:18337562] +synonym: "chemokine (C-C motif) ligand 5 signalling pathway" EXACT [GOC:mah] +synonym: "RANTES-mediated signaling pathway" EXACT [PMID:19122644] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2011-02-24T12:56:13Z + +[Term] +id: GO:0035690 +name: cellular response to drug +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease." [GOC:sl] +subset: goslim_chembl +is_a: GO:0042493 ! response to drug +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: bf +creation_date: 2011-02-24T03:37:26Z + +[Term] +id: GO:0035691 +name: macrophage migration inhibitory factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling, PMID:12782713, PMID:19413900] +synonym: "macrophage migration inhibitory factor signalling pathway" EXACT [GOC:mah] +synonym: "MIF signaling pathway" EXACT [GOC:ebc] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2011-02-25T11:31:21Z + +[Term] +id: GO:0035692 +name: macrophage migration inhibitory factor receptor complex +namespace: cellular_component +def: "A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins." [GOC:BHF, PMID:12782713, PMID:17045821] +is_a: GO:0043235 ! receptor complex +created_by: bf +creation_date: 2011-02-25T11:33:15Z + +[Term] +id: GO:0035693 +name: NOS2-CD74 complex +namespace: cellular_component +def: "A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases." [GOC:BHF, PMID:18003616] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2011-02-25T11:35:38Z + +[Term] +id: GO:0035694 +name: mitochondrial protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." [GOC:sp, PMID:21264221, PMID:21264228] +synonym: "catabolism of mitochondrial protein" EXACT [GOC:bf] +synonym: "degradation of damaged mitochondrial protein" EXACT [GOC:bf] +is_a: GO:0044257 ! cellular protein catabolic process +intersection_of: GO:0030163 ! protein catabolic process +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0007005 ! mitochondrion organization +created_by: bf +creation_date: 2011-02-28T11:06:40Z + +[Term] +id: GO:0035695 +name: mitophagy by induced vacuole formation +namespace: biological_process +def: "The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes." [GOC:autophagy, GOC:bf, GOC:sp, PMID:21264228] +comment: In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome. +synonym: "MIV-mediated mitophagy" NARROW [PMID:21264228] +is_a: GO:0000422 ! autophagy of mitochondrion +created_by: bf +creation_date: 2011-02-28T03:01:04Z + +[Term] +id: GO:0035696 +name: monocyte extravasation +namespace: biological_process +def: "The migration of a monocyte from the blood vessels into the surrounding tissue." [CL:0000576, GOC:BHF, PMID:10657654] +is_a: GO:0045123 ! cellular extravasation +is_a: GO:0071674 ! mononuclear cell migration +is_a: GO:0097529 ! myeloid leukocyte migration +created_by: bf +creation_date: 2011-02-28T03:05:52Z + +[Term] +id: GO:0035697 +name: CD8-positive, alpha-beta T cell extravasation +namespace: biological_process +def: "The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue." [CL:0000625, GOC:BHF] +is_a: GO:0072683 ! T cell extravasation +created_by: bf +creation_date: 2011-02-28T03:08:49Z + +[Term] +id: GO:0035698 +name: CD8-positive, alpha-beta cytotoxic T cell extravasation +namespace: biological_process +def: "The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue." [CL:0000794, GOC:BHF] +is_a: GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-02-28T03:09:53Z + +[Term] +id: GO:0035699 +name: T-helper 17 cell extravasation +namespace: biological_process +def: "The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue." [CL:0000899, GOC:BHF] +is_a: GO:0035684 ! helper T cell extravasation +is_a: GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-02-28T03:13:27Z + +[Term] +id: GO:0035700 +name: astrocyte chemotaxis +namespace: biological_process +def: "The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000127, GOC:BHF, PMID:12271471] +is_a: GO:0043615 ! astrocyte cell migration +is_a: GO:0060326 ! cell chemotaxis +created_by: bf +creation_date: 2011-02-28T03:17:52Z + +[Term] +id: GO:0035701 +name: hematopoietic stem cell migration +namespace: biological_process +def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092] +synonym: "hemopoietic stem cell migration" EXACT [CL:0000037] +is_a: GO:0016477 ! cell migration +created_by: bf +creation_date: 2011-02-28T03:20:36Z + +[Term] +id: GO:0035702 +name: monocyte homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000576, GOC:BHF, PMID:18832716] +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis +created_by: bf +creation_date: 2011-03-02T11:32:57Z + +[Term] +id: GO:0035703 +name: monocyte migration into blood stream +namespace: biological_process +def: "The movement of a monocyte from the bone marrow to the blood stream." [CL:0000576, GOC:BHF] +synonym: "release of monocytes into circulation" EXACT [GOC:bf] +is_a: GO:0071674 ! mononuclear cell migration +is_a: GO:0097529 ! myeloid leukocyte migration +relationship: part_of GO:0008015 ! blood circulation +created_by: bf +creation_date: 2011-03-02T11:37:54Z + +[Term] +id: GO:0035704 +name: helper T cell chemotaxis +namespace: biological_process +def: "The directed movement of a helper T cell in response to an external stimulus." [CL:0000912, GOC:BHF] +synonym: "T-helper cell chemotaxis" EXACT [CL:0000912] +is_a: GO:0010818 ! T cell chemotaxis +created_by: bf +creation_date: 2011-03-02T02:31:48Z + +[Term] +id: GO:0035705 +name: T-helper 17 cell chemotaxis +namespace: biological_process +def: "The directed movement of a T-helper 17 cell in response to an external stimulus." [CL:0000899, GOC:BHF] +synonym: "Th17 cell chemotaxis" EXACT [CL:0000899] +is_a: GO:0035704 ! helper T cell chemotaxis +created_by: bf +creation_date: 2011-03-02T02:35:16Z + +[Term] +id: GO:0035706 +name: T-helper 1 cell chemotaxis +namespace: biological_process +def: "The directed movement of a T-helper 1 cell in response to an external stimulus." [CL:0000545, GOC:BHF] +synonym: "Th1 cell chemotaxis" EXACT [CL:0000545] +is_a: GO:0035704 ! helper T cell chemotaxis +created_by: bf +creation_date: 2011-03-02T02:36:49Z + +[Term] +id: GO:0035707 +name: T-helper 2 cell chemotaxis +namespace: biological_process +def: "The directed movement of a T-helper 2 cell in response to an external stimulus." [CL:0000546, GOC:BHF] +synonym: "Th2 cell chemotaxis" EXACT [CL:0000546] +is_a: GO:0035704 ! helper T cell chemotaxis +created_by: bf +creation_date: 2011-03-02T02:37:44Z + +[Term] +id: GO:0035708 +name: interleukin-4-dependent isotype switching to IgE isotypes +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4)." [GOC:BHF, PMID:12496423] +synonym: "IL-4-dependent isotype switching to IgE isotypes" EXACT [GOC:add, GOC:bf] +is_a: GO:0048289 ! isotype switching to IgE isotypes +created_by: bf +creation_date: 2011-03-02T02:40:35Z + +[Term] +id: GO:0035709 +name: memory T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000813, GOC:BHF] +is_a: GO:0042110 ! T cell activation +created_by: bf +creation_date: 2011-03-02T03:03:02Z + +[Term] +id: GO:0035710 +name: CD4-positive, alpha-beta T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000624, GOC:BHF] +is_a: GO:0046631 ! alpha-beta T cell activation +created_by: bf +creation_date: 2011-03-02T03:04:11Z + +[Term] +id: GO:0035711 +name: T-helper 1 cell activation +namespace: biological_process +def: "The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000545, GOC:BHF] +synonym: "Th1 cell activation" EXACT [CL:0000545] +is_a: GO:0035710 ! CD4-positive, alpha-beta T cell activation +created_by: bf +creation_date: 2011-03-02T03:05:08Z + +[Term] +id: GO:0035712 +name: T-helper 2 cell activation +namespace: biological_process +def: "The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000546, GOC:BHF] +synonym: "Th2 cell activation" EXACT [CL:0000546] +is_a: GO:0035710 ! CD4-positive, alpha-beta T cell activation +created_by: bf +creation_date: 2011-03-02T03:05:59Z + +[Term] +id: GO:0035713 +name: response to nitrogen dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus." [GOC:BHF] +synonym: "response to NO2" EXACT [] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2011-03-02T03:14:51Z + +[Term] +id: GO:0035714 +name: cellular response to nitrogen dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus." [GOC:BHF] +synonym: "cellular response to NO2" EXACT [] +is_a: GO:0035713 ! response to nitrogen dioxide +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: bf +creation_date: 2011-03-02T03:16:37Z + +[Term] +id: GO:0035715 +name: chemokine (C-C motif) ligand 2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 2." [GOC:BHF] +synonym: "CCL2 binding" EXACT [GOC:ebc] +is_a: GO:0019957 ! C-C chemokine binding +created_by: bf +creation_date: 2011-03-03T04:24:24Z + +[Term] +id: GO:0035716 +name: chemokine (C-C motif) ligand 12 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 12." [GOC:BHF] +synonym: "CCL12 binding" EXACT [GOC:ebc] +is_a: GO:0019957 ! C-C chemokine binding +created_by: bf +creation_date: 2011-03-03T04:25:01Z + +[Term] +id: GO:0035717 +name: chemokine (C-C motif) ligand 7 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 7." [GOC:BHF] +synonym: "CCL7 binding" EXACT [GOC:ebc] +is_a: GO:0019957 ! C-C chemokine binding +created_by: bf +creation_date: 2011-03-03T04:25:41Z + +[Term] +id: GO:0035718 +name: macrophage migration inhibitory factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor." [GOC:BHF, PMID:19601712] +synonym: "MIF binding" EXACT [PMID:19601712] +is_a: GO:0019955 ! cytokine binding +created_by: bf +creation_date: 2011-03-03T04:27:16Z + +[Term] +id: GO:0035719 +name: tRNA import into nucleus +namespace: biological_process +def: "The directed movement of tRNA from the cytoplasm to the nucleus." [GOC:vw, PMID:20032305] +synonym: "retrograde tRNA transport into nucleus" EXACT [GOC:vw, PMID:20032305] +synonym: "tRNA nuclear import" EXACT [GOC:vw] +is_a: GO:0006404 ! RNA import into nucleus +is_a: GO:0051031 ! tRNA transport +created_by: bf +creation_date: 2011-03-03T04:32:35Z + +[Term] +id: GO:0035720 +name: intraciliary anterograde transport +namespace: biological_process +def: "The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins." [GOC:BHF, GOC:cilia, PMID:17895364] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "intraflagellar anterograde transport" EXACT [] +is_a: GO:0042073 ! intraciliary transport +created_by: bf +creation_date: 2011-03-07T11:24:53Z + +[Term] +id: GO:0035721 +name: intraciliary retrograde transport +namespace: biological_process +def: "The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins." [GOC:BHF, GOC:cilia] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "intraflagellar retrograde transport" EXACT [] +is_a: GO:0042073 ! intraciliary transport +created_by: bf +creation_date: 2011-03-07T11:25:32Z + +[Term] +id: GO:0035722 +name: interleukin-12-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling] +synonym: "IL-12-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-12-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071349 ! cellular response to interleukin-12 +created_by: bf +creation_date: 2011-03-07T11:27:58Z + +[Term] +id: GO:0035723 +name: interleukin-15-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling] +synonym: "IL-15-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-15-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071350 ! cellular response to interleukin-15 +created_by: bf +creation_date: 2011-03-07T11:28:29Z + +[Term] +id: GO:0035724 +name: CD24 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation." [GOC:BHF] +synonym: "CD24 anabolism" EXACT [GOC:bf] +synonym: "CD24 biosynthesis" EXACT [GOC:bf] +synonym: "CD24 formation" EXACT [GOC:bf] +synonym: "CD24 synthesis" EXACT [GOC:bf] +is_a: GO:0009101 ! glycoprotein biosynthetic process +created_by: bf +creation_date: 2011-03-07T11:32:54Z + +[Term] +id: GO:0035725 +name: sodium ion transmembrane transport +namespace: biological_process +def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "sodium ion membrane transport" EXACT [] +is_a: GO:0006814 ! sodium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: bf +creation_date: 2011-03-10T02:52:36Z + +[Term] +id: GO:0035726 +name: common myeloid progenitor cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage." [CL:0000049, GOC:BHF] +is_a: GO:0008283 ! cell population proliferation +created_by: bf +creation_date: 2011-03-10T02:57:19Z + +[Term] +id: GO:0035727 +name: lysophosphatidic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors." [GOC:curators] +synonym: "LPA binding" EXACT [] +is_a: GO:0005543 ! phospholipid binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: bf +creation_date: 2011-03-10T03:00:05Z + +[Term] +id: GO:0035728 +name: response to hepatocyte growth factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus." [GOC:bf] +synonym: "response to hepatocyte growth factor stimulus" EXACT [GOC:dos] +synonym: "response to HGF stimulus" EXACT [GOC:bf] +is_a: GO:0070848 ! response to growth factor +created_by: bf +creation_date: 2011-03-10T03:02:47Z + +[Term] +id: GO:0035729 +name: cellular response to hepatocyte growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus." [GOC:bf] +synonym: "cellular response to HGF stimulus" EXACT [GOC:bf] +is_a: GO:0035728 ! response to hepatocyte growth factor +is_a: GO:0071363 ! cellular response to growth factor stimulus +created_by: bf +creation_date: 2011-03-10T03:04:19Z + +[Term] +id: GO:0035730 +name: S-nitrosoglutathione binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems." [GOC:BHF] +synonym: "GSNO binding" EXACT [] +is_a: GO:1901681 ! sulfur compound binding +created_by: bf +creation_date: 2011-03-11T09:57:19Z + +[Term] +id: GO:0035731 +name: dinitrosyl-iron complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO." [GOC:BHF, PMID:10534443] +synonym: "dinitrosyl-diglutathionyl-iron complex binding" EXACT [PMID:12871931] +synonym: "DNDGIC binding" EXACT [PMID:12871931] +synonym: "DNIC binding" EXACT [PMID:10534443] +is_a: GO:0005488 ! binding +created_by: bf +creation_date: 2011-03-11T09:58:31Z + +[Term] +id: GO:0035732 +name: nitric oxide storage +namespace: biological_process +def: "The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins." [GOC:BHF, PMID:12871945] +synonym: "NO storage" EXACT [GOC:bf] +is_a: GO:0051179 ! localization +relationship: part_of GO:0033484 ! nitric oxide homeostasis +created_by: bf +creation_date: 2011-03-11T10:00:31Z + +[Term] +id: GO:0035733 +name: hepatic stellate cell activation +namespace: biological_process +def: "A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor." [CL:0000632, GOC:bf] +is_a: GO:0072537 ! fibroblast activation +created_by: bf +creation_date: 2011-03-11T10:04:12Z + +[Term] +id: GO:0035735 +name: intraciliary transport involved in cilium assembly +namespace: biological_process +def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2] +synonym: "intraciliary transport involved in cilium morphogenesis" RELATED [] +synonym: "intraflagellar transport" BROAD [] +synonym: "intraflagellar transport involved in cilium morphogenesis" RELATED [] +xref: Reactome:R-HSA-5620924.2 +is_a: GO:0042073 ! intraciliary transport +intersection_of: GO:0042073 ! intraciliary transport +intersection_of: part_of GO:0060271 ! cilium assembly +relationship: part_of GO:0060271 ! cilium assembly +created_by: bf +creation_date: 2011-03-17T10:55:42Z + +[Term] +id: GO:0035736 +name: cell proliferation involved in compound eye morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart] +is_a: GO:0008283 ! cell population proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0001745 ! compound eye morphogenesis +relationship: part_of GO:0001745 ! compound eye morphogenesis +created_by: bf +creation_date: 2011-03-17T10:57:03Z + +[Term] +id: GO:0035737 +name: injection of substance in to other organism +namespace: biological_process +def: "The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes." [GOC:pamgo_curators] +is_a: GO:0051704 ! multi-organism process +created_by: bf +creation_date: 2011-03-17T10:58:57Z + +[Term] +id: GO:0035738 +name: envenomation resulting in modulation of process in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism." [GOC:pamgo_curators] +synonym: "envenomation resulting in modification of morphology or physiology of other organism" EXACT [] +is_a: GO:0035737 ! injection of substance in to other organism +intersection_of: GO:0035737 ! injection of substance in to other organism +intersection_of: has_part GO:0035821 ! modulation of process of other organism +relationship: has_part GO:0035821 ! modulation of process of other organism +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI +created_by: bf +creation_date: 2011-03-17T10:59:27Z + +[Term] +id: GO:0035739 +name: CD4-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "The expansion of a CD4-positive, alpha-beta T cell population by cell division." [CL:0000624, GOC:BHF] +is_a: GO:0035710 ! CD4-positive, alpha-beta T cell activation +is_a: GO:0046633 ! alpha-beta T cell proliferation +created_by: bf +creation_date: 2011-03-17T02:12:48Z + +[Term] +id: GO:0035740 +name: CD8-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "The expansion of a CD8-positive, alpha-beta T cell population by cell division." [CL:0000625, GOC:BHF] +is_a: GO:0036037 ! CD8-positive, alpha-beta T cell activation +is_a: GO:0046633 ! alpha-beta T cell proliferation +created_by: bf +creation_date: 2011-03-17T02:13:54Z + +[Term] +id: GO:0035741 +name: activated CD4-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "The expansion of an activated CD4-positive, alpha-beta T cell population by cell division." [CL:0000896, GOC:BHF] +is_a: GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +created_by: bf +creation_date: 2011-03-17T02:18:39Z + +[Term] +id: GO:0035742 +name: activated CD8-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "The expansion of an activated CD8-positive, alpha-beta T cell population by cell division." [CL:0000906, GOC:BHF] +is_a: GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +created_by: bf +creation_date: 2011-03-17T02:19:58Z + +[Term] +id: GO:0035743 +name: CD4-positive, alpha-beta T cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell." [CL:0000624, GOC:BHF] +is_a: GO:0002369 ! T cell cytokine production +created_by: bf +creation_date: 2011-03-17T02:21:51Z + +[Term] +id: GO:0035744 +name: T-helper 1 cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a T-helper 1 cell." [CL:0000545, GOC:BHF] +synonym: "Th1 cell cytokine production" EXACT [CL:0000545] +is_a: GO:0035743 ! CD4-positive, alpha-beta T cell cytokine production +relationship: part_of GO:0042088 ! T-helper 1 type immune response +created_by: bf +creation_date: 2011-03-17T02:22:54Z + +[Term] +id: GO:0035745 +name: T-helper 2 cell cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a T-helper 2 cell." [CL:0000546, GOC:BHF] +synonym: "Th2 cell cytokine production" EXACT [CL:0000546] +is_a: GO:0035743 ! CD4-positive, alpha-beta T cell cytokine production +relationship: part_of GO:0042092 ! type 2 immune response +created_by: bf +creation_date: 2011-03-17T02:23:32Z + +[Term] +id: GO:0035746 +name: granzyme A production +namespace: biological_process +def: "The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0002440 ! production of molecular mediator of immune response +created_by: bf +creation_date: 2011-03-17T02:39:11Z + +[Term] +id: GO:0035747 +name: natural killer cell chemotaxis +namespace: biological_process +def: "The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000623, GOC:BHF] +is_a: GO:0048247 ! lymphocyte chemotaxis +created_by: bf +creation_date: 2011-03-17T02:40:10Z + +[Term] +id: GO:0035748 +name: myelin sheath abaxonal region +namespace: cellular_component +def: "The region of the myelin sheath furthest from the axon." [GOC:BHF, PMID:20237282] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043209 ! myelin sheath +created_by: bf +creation_date: 2011-03-23T10:16:14Z + +[Term] +id: GO:0035749 +name: myelin sheath adaxonal region +namespace: cellular_component +def: "The region of the myelin sheath nearest to the axon." [GOC:BHF, PMID:20237282] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043209 ! myelin sheath +created_by: bf +creation_date: 2011-03-23T10:17:42Z + +[Term] +id: GO:0035750 +name: protein localization to myelin sheath abaxonal region +namespace: biological_process +def: "Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon." [GOC:BHF, PMID:20237282] +synonym: "protein localisation to myelin sheath abaxonal region" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +created_by: bf +creation_date: 2011-03-23T10:20:06Z + +[Term] +id: GO:0035751 +name: regulation of lysosomal lumen pH +namespace: biological_process +def: "Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion." [GOC:rph] +is_a: GO:0051453 ! regulation of intracellular pH +relationship: part_of GO:0007040 ! lysosome organization +created_by: bf +creation_date: 2011-03-23T10:23:41Z + +[Term] +id: GO:0035752 +name: lysosomal lumen pH elevation +namespace: biological_process +def: "Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion." [GOC:bf, GOC:rph] +synonym: "lysosome pH elevation" EXACT [GOC:bf, GOC:rph] +is_a: GO:0035751 ! regulation of lysosomal lumen pH +is_a: GO:0051454 ! intracellular pH elevation +created_by: bf +creation_date: 2011-03-23T10:24:24Z + +[Term] +id: GO:0035753 +name: maintenance of DNA trinucleotide repeats +namespace: biological_process +def: "Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs." [GOC:rb, PMID:21347277, SO:0000291] +is_a: GO:0043570 ! maintenance of DNA repeat elements +created_by: bf +creation_date: 2011-03-23T10:29:02Z + +[Term] +id: GO:0035754 +name: B cell chemotaxis +namespace: biological_process +def: "The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000236, GOC:BHF] +is_a: GO:0048247 ! lymphocyte chemotaxis +created_by: bf +creation_date: 2011-03-23T10:30:33Z + +[Term] +id: GO:0035755 +name: cardiolipin hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA)." [GOC:sp, PMID:17028579, PMID:21397848] +xref: Reactome:R-HSA-8954398 "PLD6 dimer hydrolyses cardiolipin to PA and PG" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity +created_by: bf +creation_date: 2011-03-24T10:14:05Z + +[Term] +id: GO:0035756 +name: transepithelial migration of symbiont in host +namespace: biological_process +def: "The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, PMID:10639460] +synonym: "migration in host through an epithelial cell layer" EXACT [GOC:bf] +synonym: "migration of symbiont within host by transepithelial trafficking" EXACT [GOC:bf] +is_a: GO:0044001 ! migration in host +created_by: bf +creation_date: 2011-03-24T10:20:03Z + +[Term] +id: GO:0035757 +name: chemokine (C-C motif) ligand 19 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19." [GOC:BHF] +synonym: "CCL19 binding" EXACT [GOC:bf] +is_a: GO:0019957 ! C-C chemokine binding +created_by: bf +creation_date: 2011-03-25T02:02:36Z + +[Term] +id: GO:0035758 +name: chemokine (C-C motif) ligand 21 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21." [GOC:BHF] +synonym: "CCL21 binding" EXACT [GOC:bf] +is_a: GO:0019957 ! C-C chemokine binding +created_by: bf +creation_date: 2011-03-25T02:03:53Z + +[Term] +id: GO:0035759 +name: mesangial cell-matrix adhesion +namespace: biological_process +def: "The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney." [CL:0000650, GOC:BHF, PMID:15569314] +is_a: GO:0007160 ! cell-matrix adhesion +created_by: bf +creation_date: 2011-03-25T02:06:21Z + +[Term] +id: GO:0035760 +name: cytoplasmic polyadenylation-dependent rRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate." [PMID:20368444] +synonym: "cytoplasmic poly(A)-dependent rRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0016075 ! rRNA catabolic process +is_a: GO:0043634 ! polyadenylation-dependent ncRNA catabolic process +created_by: bf +creation_date: 2011-03-25T02:14:50Z + +[Term] +id: GO:0035761 +name: dorsal motor nucleus of vagus nerve maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state." [GOC:dgh] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0021744 ! dorsal motor nucleus of vagus nerve development +created_by: bf +creation_date: 2011-03-29T02:45:50Z + +[Term] +id: GO:0035762 +name: dorsal motor nucleus of vagus nerve morphogenesis +namespace: biological_process +def: "The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dgh] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021744 ! dorsal motor nucleus of vagus nerve development +created_by: bf +creation_date: 2011-03-29T02:47:18Z + +[Term] +id: GO:0035763 +name: dorsal motor nucleus of vagus nerve structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh] +synonym: "dorsal motor nucleus of vagus nerve structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0035762 ! dorsal motor nucleus of vagus nerve morphogenesis +created_by: bf +creation_date: 2011-03-29T02:47:56Z + +[Term] +id: GO:0035764 +name: dorsal motor nucleus of vagus nerve formation +namespace: biological_process +def: "The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dgh] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035762 ! dorsal motor nucleus of vagus nerve morphogenesis +created_by: bf +creation_date: 2011-03-29T02:48:26Z + +[Term] +id: GO:0035765 +name: motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation +namespace: biological_process +def: "The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve." [GOC:dgh, PMID:21262462] +is_a: GO:0021535 ! cell migration in hindbrain +intersection_of: GO:0021535 ! cell migration in hindbrain +intersection_of: part_of GO:0035764 ! dorsal motor nucleus of vagus nerve formation +relationship: part_of GO:0035764 ! dorsal motor nucleus of vagus nerve formation +created_by: bf +creation_date: 2011-03-29T02:52:09Z + +[Term] +id: GO:0035766 +name: cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF)." [GOC:BHF] +is_a: GO:0060326 ! cell chemotaxis +relationship: part_of GO:0044344 ! cellular response to fibroblast growth factor stimulus +created_by: bf +creation_date: 2011-03-31T04:30:16Z + +[Term] +id: GO:0035767 +name: endothelial cell chemotaxis +namespace: biological_process +def: "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [CL:0000115, GOC:BHF] +is_a: GO:0043542 ! endothelial cell migration +is_a: GO:0060326 ! cell chemotaxis +created_by: bf +creation_date: 2011-03-31T04:31:37Z + +[Term] +id: GO:0035768 +name: endothelial cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF)." [CL:0000115, GOC:BHF] +is_a: GO:0035766 ! cell chemotaxis to fibroblast growth factor +is_a: GO:0035767 ! endothelial cell chemotaxis +created_by: bf +creation_date: 2011-03-31T04:32:17Z + +[Term] +id: GO:0035769 +name: B cell chemotaxis across high endothelial venule +namespace: biological_process +def: "The movement of a B cell to cross a high endothelial venule in response to an external stimulus." [CL:0000236, GOC:BHF] +synonym: "B-cell chemotaxis across high endothelial venule" EXACT [GOC:ebc] +is_a: GO:0002518 ! lymphocyte chemotaxis across high endothelial venule +is_a: GO:0035754 ! B cell chemotaxis +created_by: bf +creation_date: 2011-04-01T10:48:59Z + +[Term] +id: GO:0035770 +name: ribonucleoprotein granule +namespace: cellular_component +def: "A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions." [GOC:go_curators, GOC:sp, PMID:16520386, PMID:20368989, PMID:21436445] +synonym: "mRNP granule" EXACT [] +synonym: "RNA granule" NARROW [] +synonym: "RNP granule" EXACT [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +is_a: GO:0099080 ! supramolecular complex +created_by: bf +creation_date: 2011-04-01T10:50:47Z + +[Term] +id: GO:0035771 +name: interleukin-4-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling] +synonym: "IL-4-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-4-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071353 ! cellular response to interleukin-4 +created_by: bf +creation_date: 2011-04-01T10:56:46Z + +[Term] +id: GO:0035772 +name: interleukin-13-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling] +synonym: "IL-13-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-13-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0035963 ! cellular response to interleukin-13 +created_by: bf +creation_date: 2011-04-01T11:00:11Z + +[Term] +id: GO:0035773 +name: insulin secretion involved in cellular response to glucose stimulus +namespace: biological_process +def: "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus." [GOC:bf, GOC:yaf, PMID:8492079] +synonym: "insulin secretion involved in cellular response to glucose" EXACT [GOC:bf] +is_a: GO:0030073 ! insulin secretion +is_a: GO:0051649 ! establishment of localization in cell +intersection_of: GO:0030073 ! insulin secretion +intersection_of: part_of GO:0071333 ! cellular response to glucose stimulus +relationship: part_of GO:0071333 ! cellular response to glucose stimulus +created_by: bf +creation_date: 2011-04-01T01:14:40Z + +[Term] +id: GO:0035774 +name: positive regulation of insulin secretion involved in cellular response to glucose stimulus +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:bf, GOC:yaf] +synonym: "positive regulation of insulin secretion in response to glucose" EXACT [GOC:bf] +is_a: GO:0032024 ! positive regulation of insulin secretion +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0061178 ! regulation of insulin secretion involved in cellular response to glucose stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +relationship: positively_regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +created_by: bf +creation_date: 2011-04-01T01:49:09Z + +[Term] +id: GO:0035775 +name: pronephric glomerulus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] +comment: This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus. +is_a: GO:0072102 ! glomerulus morphogenesis +relationship: part_of GO:0039021 ! pronephric glomerulus development +created_by: bf +creation_date: 2011-04-04T10:59:28Z + +[Term] +id: GO:0035776 +name: pronephric proximal tubule development +namespace: biological_process +def: "The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] +is_a: GO:0039020 ! pronephric nephron tubule development +is_a: GO:0072014 ! proximal tubule development +created_by: bf +creation_date: 2011-04-04T11:02:54Z + +[Term] +id: GO:0035777 +name: pronephric distal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] +is_a: GO:0039020 ! pronephric nephron tubule development +is_a: GO:0072017 ! distal tubule development +created_by: bf +creation_date: 2011-04-04T11:06:01Z + +[Term] +id: GO:0035778 +name: pronephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] +is_a: GO:0039014 ! cell differentiation involved in pronephros development +is_a: GO:0072160 ! nephron tubule epithelial cell differentiation +relationship: part_of GO:0039020 ! pronephric nephron tubule development +created_by: bf +creation_date: 2011-04-04T11:07:47Z + +[Term] +id: GO:0035779 +name: angioblast cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf] +synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566] +is_a: GO:0048863 ! stem cell differentiation +relationship: part_of GO:0001568 ! blood vessel development +created_by: bf +creation_date: 2011-04-04T11:10:38Z + +[Term] +id: GO:0035780 +name: CD80 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival." [GOC:BHF, GOC:ebc] +synonym: "CD80 anabolism" EXACT [GOC:bf] +synonym: "CD80 biosynthesis" EXACT [GOC:bf] +synonym: "CD80 formation" EXACT [GOC:bf] +synonym: "CD80 synthesis" EXACT [GOC:bf] +is_a: GO:0009101 ! glycoprotein biosynthetic process +created_by: bf +creation_date: 2011-04-04T11:18:41Z + +[Term] +id: GO:0035781 +name: CD86 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival." [GOC:BHF, GOC:ebc] +synonym: "CD86 anabolism" EXACT [GOC:bf] +synonym: "CD86 biosynthesis" EXACT [GOC:bf] +synonym: "CD86 formation" EXACT [GOC:bf] +synonym: "CD86 synthesis" EXACT [GOC:bf] +is_a: GO:0009101 ! glycoprotein biosynthetic process +created_by: bf +creation_date: 2011-04-04T11:20:40Z + +[Term] +id: GO:0035782 +name: mature natural killer cell chemotaxis +namespace: biological_process +def: "The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules." [CL:0000824, GOC:BHF] +synonym: "activated natural killer cell chemotaxis" EXACT [GOC:ebc] +is_a: GO:0035747 ! natural killer cell chemotaxis +created_by: bf +creation_date: 2011-04-04T11:23:13Z + +[Term] +id: GO:0035783 +name: CD4-positive, alpha-beta T cell costimulation +namespace: biological_process +def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation." [CL:0000624, GOC:BHF, GOC:pr] +synonym: "CD4-positive, alpha beta T cell costimulation" EXACT [] +is_a: GO:0031295 ! T cell costimulation +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +created_by: bf +creation_date: 2011-04-04T11:28:52Z + +[Term] +id: GO:0035784 +name: nickel cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell." [GOC:kmv] +synonym: "nickel homeostasis" EXACT [GOC:bf] +is_a: GO:0055076 ! transition metal ion homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis +created_by: bf +creation_date: 2011-04-05T09:55:14Z + +[Term] +id: GO:0035785 +name: cellular nickel ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell." [GOC:kmv] +synonym: "cellular nickel homeostasis" EXACT [GOC:bf] +is_a: GO:0035784 ! nickel cation homeostasis +is_a: GO:0046916 ! cellular transition metal ion homeostasis +is_a: GO:0072503 ! cellular divalent inorganic cation homeostasis +created_by: bf +creation_date: 2011-04-05T09:55:56Z + +[Term] +id: GO:0035787 +name: cell migration involved in kidney development +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] +is_a: GO:0016477 ! cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +created_by: bf +creation_date: 2011-04-06T10:39:52Z + +[Term] +id: GO:0035788 +name: cell migration involved in metanephros development +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] +synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf] +is_a: GO:0035787 ! cell migration involved in kidney development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: bf +creation_date: 2011-04-06T10:42:21Z + +[Term] +id: GO:0035789 +name: metanephric mesenchymal cell migration +namespace: biological_process +def: "The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:10734101, PMID:19019919] +synonym: "metanephric mesenchyme chemotaxis" NARROW [PMID:19019919] +is_a: GO:0035788 ! cell migration involved in metanephros development +created_by: bf +creation_date: 2011-04-06T10:45:15Z + +[Term] +id: GO:0035790 +name: platelet-derived growth factor receptor-alpha signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:yaf, PMID:10372961, PR:000002030] +synonym: "alphaPDGF receptor signaling pathway" EXACT [PMID:10372961] +synonym: "PDGF receptor-alpha signaling pathway" EXACT [GOC:bf] +synonym: "PDGFR-alpha signaling pathway" RELATED [GOC:bf] +synonym: "platelet-derived growth factor receptor-alpha signalling pathway" EXACT [GOC:mah] +is_a: GO:0048008 ! platelet-derived growth factor receptor signaling pathway +created_by: bf +creation_date: 2011-04-06T10:55:16Z + +[Term] +id: GO:0035791 +name: platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:signaling, GOC:yaf, PMID:10372961, PR:000002035] +synonym: "betaPDGF receptor signaling pathway" EXACT [PMID:10372961] +synonym: "PDGF receptor-beta signaling pathway" EXACT [GOC:bf] +synonym: "PDGFR-beta signaling pathway" EXACT [GOC:bf] +synonym: "platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +is_a: GO:0048008 ! platelet-derived growth factor receptor signaling pathway +created_by: bf +creation_date: 2011-04-06T10:57:04Z + +[Term] +id: GO:0035792 +name: host cell postsynaptic membrane +namespace: cellular_component +def: "A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane." [GOC:ecd] +synonym: "other organism post-synaptic membrane" EXACT [] +synonym: "other organism postsynaptic membrane" RELATED [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0033644 ! host cell membrane +created_by: bf +creation_date: 2011-04-08T01:21:20Z + +[Term] +id: GO:0035793 +name: positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:10734101] +synonym: "positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway" EXACT [PMID:10734101] +synonym: "positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway" EXACT [GOC:bf] +synonym: "positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway" EXACT [GOC:bf] +synonym: "positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +is_a: GO:1900238 ! regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway +is_a: GO:2000591 ! positive regulation of metanephric mesenchymal cell migration +intersection_of: GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +intersection_of: positively_regulates GO:0035789 ! metanephric mesenchymal cell migration +created_by: bf +creation_date: 2011-04-11T01:30:03Z + +[Term] +id: GO:0035794 +name: positive regulation of mitochondrial membrane permeability +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane." [GOC:bf, PMID:12546810] +synonym: "mitochondrial membrane permeability transition" NARROW [PMID:17136322] +synonym: "mitochondrial membrane permeabilization" NARROW [PMID:12546810] +synonym: "mitochondrial permeability transition" NARROW [PMID:21424245] +synonym: "MPT" NARROW [] +synonym: "positive regulation of transport across mitochondrial membrane" EXACT [GOC:bf] +is_a: GO:0046902 ! regulation of mitochondrial membrane permeability +is_a: GO:1905710 ! positive regulation of membrane permeability +created_by: bf +creation_date: 2011-04-11T01:44:06Z + +[Term] +id: GO:0035795 +name: negative regulation of mitochondrial membrane permeability +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane." [PMID:10781072] +synonym: "mitochondrial membrane impermeability" RELATED [PMID:10781072] +synonym: "mitochondrial membrane impermeabilization" NARROW [GOC:bf] +synonym: "negative regulation of transport across mitochondrial membrane" EXACT [GOC:bf] +is_a: GO:0046902 ! regulation of mitochondrial membrane permeability +is_a: GO:1905709 ! negative regulation of membrane permeability +created_by: bf +creation_date: 2011-04-11T01:45:26Z + +[Term] +id: GO:0035796 +name: ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing +namespace: cellular_component +def: "A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [PMID:18931129, PMID:20972419, PMID:21135102] +comment: The ECF-type transporters differs from other types of ABC transporters because the substrate-binding subunit lies integral to the membrane. +synonym: "ATP-binding cassette (ABC) transporter complex, ECF-type" EXACT [GOC:bf] +synonym: "energy coupling factor (ECF)-type ABC transporter" EXACT [PMID:21135102] +synonym: "energy-coupling factor transporter" EXACT [PMID:18931129] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +created_by: bf +creation_date: 2011-04-11T02:02:41Z + +[Term] +id: GO:0035797 +name: tellurite methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride)." [GOC:bf, GOC:kad, PMID:11053398, PMID:21244361] +synonym: "S-adenosyl-L-methionine-dependent tellurite methyltransferase activity" EXACT [GOC:bf] +synonym: "SAM-dependent tellurite methyltransferase activity" EXACT [GOC:bf] +synonym: "tellurite methylase activity" BROAD [GOC:bf] +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: bf +creation_date: 2011-04-14T01:06:19Z + +[Term] +id: GO:0035798 +name: 2-alkenal reductase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+." [GOC:bf, GOC:kad, PMID:16299173] +synonym: "NADPH:2-alkenal alpha,beta-hydrogenase activity" EXACT [GOC:bf, GOC:kad] +is_a: GO:0032440 ! 2-alkenal reductase [NAD(P)+] activity +created_by: bf +creation_date: 2011-04-14T01:11:07Z + +[Term] +id: GO:0035799 +name: ureter maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463] +is_a: GO:0048799 ! animal organ maturation +relationship: part_of GO:0072189 ! ureter development +created_by: bf +creation_date: 2011-04-14T01:13:39Z + +[Term] +id: GO:0035800 +name: deubiquitinase activator activity +namespace: molecular_function +def: "Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences." [GOC:sart, ISBN:0120793709] +is_a: GO:0016504 ! peptidase activator activity +relationship: part_of GO:2000158 ! positive regulation of ubiquitin-specific protease activity +creation_date: 2011-04-18T10:20:15Z + +[Term] +id: GO:0035801 +name: adrenal cortex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens)." [PMID:12185666, PMID:21115154, Wikipedia:Adrenal_cortex] +synonym: "adrenal gland cortex development" EXACT [MA:0000118] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030325 ! adrenal gland development +created_by: bf +creation_date: 2011-04-18T10:25:39Z + +[Term] +id: GO:0035802 +name: adrenal cortex formation +namespace: biological_process +def: "The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate)." [PMID:12185666, PMID:21115154] +synonym: "adrenal gland cortex formation" EXACT [MA:0000118] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035801 ! adrenal cortex development +created_by: bf +creation_date: 2011-04-18T10:26:49Z + +[Term] +id: GO:0035803 +name: egg coat formation +namespace: biological_process +def: "Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [GOC:bf, GOC:sart, GOC:yaf, PMID:16944418, PMID:17163408] +synonym: "VE formation" NARROW [PMID:16944418, PMID:17163408] +synonym: "vitelline envelope formation" NARROW [PMID:16944418] +synonym: "zona pellucida assembly" NARROW [GOC:yaf, PMID:18420282] +synonym: "ZP assembly" NARROW [PMID:18420282] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0048477 ! oogenesis +created_by: bf +creation_date: 2011-04-19T01:48:43Z + +[Term] +id: GO:0035804 +name: structural constituent of egg coat +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408] +synonym: "structural constituent of vitelline envelope" NARROW [PMID:16944418, PMID:17163408] +synonym: "structural constituent of zona pellucida" NARROW [PMID:16944418, PMID:17163408] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0035805 ! egg coat +relationship: occurs_in GO:0035805 ! egg coat +created_by: bf +creation_date: 2011-04-19T01:56:06Z + +[Term] +id: GO:0035805 +name: egg coat +namespace: cellular_component +def: "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408] +synonym: "vitelline membrane" NARROW [PMID:16944418, PMID:17163408] +synonym: "zona pellucida" NARROW [PMID:16944418, PMID:17163408] +is_a: GO:0030312 ! external encapsulating structure +created_by: bf +creation_date: 2011-04-19T02:07:23Z + +[Term] +id: GO:0035806 +name: modulation of blood coagulation in other organism +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:bf, GOC:fj] +synonym: "modulation by organism of blood clotting in other organism" EXACT [GOC:bf] +synonym: "modulation by organism of blood coagulation in other organism" EXACT [GOC:bf] +synonym: "regulation by organism of blood clotting in other organism" EXACT [GOC:bf] +synonym: "regulation of blood clotting in other organism" EXACT [GOC:bf] +synonym: "regulation of blood coagulation in other organism" EXACT [GOC:bf] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:0035821 ! modulation of process of other organism +created_by: bf +creation_date: 2011-04-20T11:38:49Z + +[Term] +id: GO:0035807 +name: positive regulation of blood coagulation in other organism +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:bf, GOC:fj, PMID:12362232] +synonym: "positive regulation by organism of blood clotting in other organism" EXACT [GOC:bf] +synonym: "positive regulation by organism of blood coagulation in other organism" EXACT [GOC:bf] +synonym: "positive regulation of blood clotting in other organism" EXACT [GOC:bf] +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:0035806 ! modulation of blood coagulation in other organism +created_by: bf +creation_date: 2011-04-20T11:43:37Z + +[Term] +id: GO:0035808 +name: meiotic recombination initiation complex +namespace: cellular_component +def: "A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins." [GOC:vw, PMID:12897161, PMID:20364342, PMID:21429938] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000794 ! condensed nuclear chromosome +created_by: bf +creation_date: 2011-04-20T11:52:50Z + +[Term] +id: GO:0035809 +name: regulation of urine volume +namespace: biological_process +def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] +synonym: "regulation of urinary volume" EXACT [] +synonym: "regulation of urine flow" EXACT [] +is_a: GO:0003014 ! renal system process +is_a: GO:0050878 ! regulation of body fluid levels +created_by: bf +creation_date: 2011-04-20T01:17:38Z + +[Term] +id: GO:0035810 +name: positive regulation of urine volume +namespace: biological_process +def: "Any process that increases the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] +synonym: "diuresis" BROAD [GOC:mtg_25march11] +synonym: "elevation of urinary volume" EXACT [GOC:mtg_25march11] +synonym: "increase in urine flow" EXACT [GOC:mtg_25march11] +is_a: GO:0035809 ! regulation of urine volume +created_by: bf +creation_date: 2011-04-20T01:19:38Z + +[Term] +id: GO:0035811 +name: negative regulation of urine volume +namespace: biological_process +def: "Any process that decreases the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] +synonym: "antidiuresis" BROAD [GOC:mtg_25march11] +synonym: "decrease in urine flow" EXACT [GOC:mtg_25march11] +synonym: "reduction of urinary volume" EXACT [GOC:mtg_25march11] +is_a: GO:0035809 ! regulation of urine volume +created_by: bf +creation_date: 2011-04-20T01:21:01Z + +[Term] +id: GO:0035812 +name: renal sodium excretion +namespace: biological_process +def: "The elimination by an organism of sodium in the urine." [GOC:mtg_25march11, GOC:yaf] +is_a: GO:0003014 ! renal system process +is_a: GO:0007588 ! excretion +relationship: part_of GO:0055078 ! sodium ion homeostasis +created_by: bf +creation_date: 2011-04-20T01:24:16Z + +[Term] +id: GO:0035813 +name: regulation of renal sodium excretion +namespace: biological_process +def: "Any process that modulates the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf] +is_a: GO:0044062 ! regulation of excretion +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035812 ! renal sodium excretion +relationship: regulates GO:0035812 ! renal sodium excretion +created_by: bf +creation_date: 2011-04-20T01:26:30Z + +[Term] +id: GO:0035814 +name: negative regulation of renal sodium excretion +namespace: biological_process +def: "Any process that decreases the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf] +comment: The amount of sodium excreted in urine over a unit of time can be decreased by decreasing the volume of urine produced (antidiuresis) and/or by decreasing the concentration of sodium in the urine. +is_a: GO:0035813 ! regulation of renal sodium excretion +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035812 ! renal sodium excretion +relationship: negatively_regulates GO:0035812 ! renal sodium excretion +created_by: bf +creation_date: 2011-04-20T01:27:39Z + +[Term] +id: GO:0035815 +name: positive regulation of renal sodium excretion +namespace: biological_process +def: "Any process that increases the amount of sodium excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf] +comment: The amount of sodium excreted in urine over a unit of time can be increased by increasing the volume of urine produced (diuresis) and/or by increasing the concentration of sodium in the urine. +synonym: "natriuresis" BROAD [GOC:mtg_25march11] +is_a: GO:0035813 ! regulation of renal sodium excretion +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035812 ! renal sodium excretion +relationship: positively_regulates GO:0035812 ! renal sodium excretion +created_by: bf +creation_date: 2011-04-20T01:29:26Z + +[Term] +id: GO:0035816 +name: renal water absorption involved in negative regulation of urine volume +namespace: biological_process +def: "Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time." [GOC:mtg_25march11, GOC:yaf] +is_a: GO:0070295 ! renal water absorption +intersection_of: GO:0070295 ! renal water absorption +intersection_of: part_of GO:0035811 ! negative regulation of urine volume +relationship: part_of GO:0035811 ! negative regulation of urine volume +created_by: bf +creation_date: 2011-04-20T01:37:34Z + +[Term] +id: GO:0035817 +name: renal sodium ion absorption involved in negative regulation of renal sodium excretion +namespace: biological_process +def: "Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time." [GOC:mtg_25march11, GOC:yaf] +is_a: GO:0070294 ! renal sodium ion absorption +intersection_of: GO:0070294 ! renal sodium ion absorption +intersection_of: part_of GO:0035814 ! negative regulation of renal sodium excretion +relationship: part_of GO:0035814 ! negative regulation of renal sodium excretion +created_by: bf +creation_date: 2011-04-20T01:40:11Z + +[Term] +id: GO:0035818 +name: positive regulation of urine volume by pressure natriuresis +namespace: biological_process +def: "An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis." [GOC:mtg_25march11, GOC:yaf] +synonym: "diuresis resulting from pressure natriuresis" RELATED [GOC:mtg_25march11] +is_a: GO:0003095 ! pressure natriuresis +is_a: GO:0035810 ! positive regulation of urine volume +created_by: bf +creation_date: 2011-04-20T01:55:42Z + +[Term] +id: GO:0035819 +name: positive regulation of renal sodium excretion by pressure natriuresis +namespace: biological_process +def: "An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis." [GOC:mtg_25march11, GOC:yaf] +synonym: "natriuresis resulting from pressure natriuresis" RELATED [] +is_a: GO:0003095 ! pressure natriuresis +is_a: GO:0035815 ! positive regulation of renal sodium excretion +intersection_of: GO:0003095 ! pressure natriuresis +intersection_of: positively_regulates GO:0035812 ! renal sodium excretion +created_by: bf +creation_date: 2011-04-20T01:57:20Z + +[Term] +id: GO:0035820 +name: negative regulation of renal sodium excretion by angiotensin +namespace: biological_process +def: "The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time." [GOC:mtg_25march11, GOC:yaf] +is_a: GO:0003083 ! negative regulation of renal output by angiotensin +is_a: GO:0035814 ! negative regulation of renal sodium excretion +created_by: bf +creation_date: 2011-04-20T02:10:50Z + +[Term] +id: GO:0035821 +name: modulation of process of other organism +namespace: biological_process +def: "The process in which an organism effects a change in the structure or processes of another organism." [GOC:bf] +synonym: "modification of morphology or physiology of other organism" EXACT [] +synonym: "regulation of morphology of other organism" NARROW [GOC:bf] +synonym: "regulation of morphology or physiology of other organism" RELATED [GOC:bf] +synonym: "regulation of physiological process of other organism" NARROW [GOC:bf] +synonym: "regulation of physiology of other organism" NARROW [GOC:bf] +is_a: GO:0044419 ! interspecies interaction between organisms +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI +created_by: bf +creation_date: 2011-04-21T01:31:51Z + +[Term] +id: GO:0035822 +name: gene conversion +namespace: biological_process +def: "A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor." [GOC:mah, PMID:17846636] +is_a: GO:0006310 ! DNA recombination +created_by: bf +creation_date: 2011-05-04T01:04:39Z + +[Term] +id: GO:0035823 +name: short tract gene conversion +namespace: biological_process +def: "A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor." [GOC:mah, PMID:16954385] +is_a: GO:0035822 ! gene conversion +created_by: bf +creation_date: 2011-05-04T01:05:35Z + +[Term] +id: GO:0035824 +name: long tract gene conversion +namespace: biological_process +def: "A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor." [GOC:mah, PMID:16954385] +is_a: GO:0035822 ! gene conversion +created_by: bf +creation_date: 2011-05-04T01:06:18Z + +[Term] +id: GO:0035825 +name: homologous recombination +namespace: biological_process +def: "A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules." [GOC:mah, PMID:11139492, PMID:17304215] +synonym: "chromosomal crossover" RELATED [GOC:mah, Wikipedia:Chromosomal_crossover] +synonym: "interchromosomal DNA recombination" EXACT [] +synonym: "interstrand DNA recombination" EXACT [] +synonym: "reciprocal DNA recombination" NARROW [] +xref: Wikipedia:Chromosomal_crossover +is_a: GO:0006310 ! DNA recombination +created_by: bf +creation_date: 2011-05-04T01:23:31Z + +[Term] +id: GO:0035826 +name: obsolete rubidium ion transport +namespace: biological_process +def: "OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "Rb+ transport" EXACT [] +synonym: "rubidium cation transport" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2011-05-04T02:53:27Z + +[Term] +id: GO:0035827 +name: obsolete rubidium ion transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "Rb+ transmembrane transporter activity" EXACT [] +synonym: "rubidium cation transmembrane transporter activity" EXACT [] +synonym: "rubidium transmembrane transporter activity" RELATED [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2011-05-04T02:55:30Z + +[Term] +id: GO:0035828 +name: obsolete renal rubidium ion transport +namespace: biological_process +def: "OBSOLETE. The directed movement of rubidium ions (Rb+) by the kidney." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "renal Rb+ transport" EXACT [] +synonym: "renal rubidium cation transport" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2011-05-04T02:58:50Z + +[Term] +id: GO:0035829 +name: obsolete renal rubidium ion absorption +namespace: biological_process +def: "OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "renal Rb+ absorption" EXACT [] +synonym: "renal rubidium cation absorption" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2011-05-04T03:01:05Z + +[Term] +id: GO:0035830 +name: palmatine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants." [GOC:yaf] +synonym: "palmatine metabolism" EXACT [GOC:bf] +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +created_by: bf +creation_date: 2011-05-04T03:04:38Z + +[Term] +id: GO:0035831 +name: palmatine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants." [GOC:yaf] +synonym: "palmatine anabolism" EXACT [GOC:bf] +synonym: "palmatine biosynthesis" EXACT [GOC:bf] +synonym: "palmatine formation" EXACT [GOC:bf] +synonym: "palmatine synthesis" EXACT [GOC:bf] +is_a: GO:0033075 ! isoquinoline alkaloid biosynthetic process +is_a: GO:0035830 ! palmatine metabolic process +created_by: bf +creation_date: 2011-05-04T03:06:06Z + +[Term] +id: GO:0035832 +name: berbamunine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid." [GOC:yaf] +synonym: "berbamunine metabolism" EXACT [GOC:bf] +is_a: GO:0046445 ! benzyl isoquinoline alkaloid metabolic process +created_by: bf +creation_date: 2011-05-04T03:11:18Z + +[Term] +id: GO:0035833 +name: berbamunine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid." [GOC:yaf] +synonym: "berbamunine anabolism" EXACT [GOC:bf] +synonym: "berbamunine biosynthesis" EXACT [GOC:bf] +synonym: "berbamunine formation" EXACT [GOC:bf] +synonym: "berbamunine synthesis" EXACT [GOC:bf] +is_a: GO:0009708 ! benzyl isoquinoline alkaloid biosynthetic process +is_a: GO:0035832 ! berbamunine metabolic process +created_by: bf +creation_date: 2011-05-04T03:12:03Z + +[Term] +id: GO:0035834 +name: indole alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] +synonym: "indole alkaloid metabolism" EXACT [GOC:bf] +is_a: GO:0009820 ! alkaloid metabolic process +created_by: bf +creation_date: 2011-05-04T03:17:44Z + +[Term] +id: GO:0035835 +name: indole alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] +synonym: "indole alkaloid anabolism" EXACT [GOC:bf] +synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] +synonym: "indole alkaloid formation" EXACT [GOC:bf] +synonym: "indole alkaloid synthesis" EXACT [GOC:bf] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0035834 ! indole alkaloid metabolic process +created_by: bf +creation_date: 2011-05-04T03:18:31Z + +[Term] +id: GO:0035836 +name: ergot alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid." [GOC:yaf] +synonym: "ergot alkaloid metabolism" EXACT [GOC:bf] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046447 ! terpenoid indole alkaloid metabolic process +created_by: bf +creation_date: 2011-05-04T03:23:13Z + +[Term] +id: GO:0035837 +name: ergot alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an ergot alkaloid." [GOC:yaf] +synonym: "ergot alkaloid anabolism" EXACT [GOC:bf] +synonym: "ergot alkaloid biosynthesis" EXACT [GOC:bf] +synonym: "ergot alkaloid formation" EXACT [GOC:bf] +synonym: "ergot alkaloid synthesis" EXACT [GOC:bf] +is_a: GO:0009709 ! terpenoid indole alkaloid biosynthetic process +is_a: GO:0035836 ! ergot alkaloid metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +created_by: bf +creation_date: 2011-05-04T03:23:57Z + +[Term] +id: GO:0035838 +name: growing cell tip +namespace: cellular_component +def: "The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs." [GOC:mah] +synonym: "growing cell end" EXACT [GOC:mah] +is_a: GO:0030427 ! site of polarized growth +is_a: GO:0051286 ! cell tip +created_by: bf +creation_date: 2011-05-06T01:28:44Z + +[Term] +id: GO:0035839 +name: non-growing cell tip +namespace: cellular_component +def: "A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures." [GOC:expert_jd, GOC:mah] +synonym: "new cell end" RELATED [GOC:mah] +synonym: "non-growing cell end" EXACT [GOC:mah] +is_a: GO:0051286 ! cell tip +created_by: bf +creation_date: 2011-05-06T01:32:21Z + +[Term] +id: GO:0035840 +name: old growing cell tip +namespace: cellular_component +def: "A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures." [GOC:expert_jd, GOC:mah] +synonym: "old growing cell end" EXACT [GOC:mah] +is_a: GO:0035838 ! growing cell tip +created_by: bf +creation_date: 2011-05-06T01:33:54Z + +[Term] +id: GO:0035841 +name: new growing cell tip +namespace: cellular_component +def: "A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth." [GOC:expert_jd, GOC:mah, PMID:19431238] +synonym: "new cell tip after activation of bipolar cell growth" EXACT [GOC:bf] +synonym: "post-NETO new cell end" EXACT [GOC:mah] +synonym: "post-NETO new cell tip" EXACT [GOC:mah] +synonym: "post-new end take-off new cell tip" EXACT [GOC:mah] +is_a: GO:0035838 ! growing cell tip +created_by: bf +creation_date: 2011-05-06T01:35:07Z + +[Term] +id: GO:0035842 +name: old cell tip after activation of bipolar cell growth +namespace: cellular_component +def: "A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures." [GOC:expert_jd, GOC:mah] +synonym: "post-NETO old cell end" EXACT [GOC:mah] +synonym: "post-NETO old cell tip" EXACT [GOC:mah] +synonym: "post-new end take-off old cell tip" EXACT [GOC:mah] +is_a: GO:0035840 ! old growing cell tip +created_by: bf +creation_date: 2011-05-06T01:37:23Z + +[Term] +id: GO:0035843 +name: endonuclear canal +namespace: cellular_component +def: "A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope." [GOC:bf, PMID:18359585] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0001673 ! male germ cell nucleus +created_by: bf +creation_date: 2011-05-06T01:45:03Z + +[Term] +id: GO:0035844 +name: cloaca development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089] +synonym: "cloacal development" EXACT [GOC:bf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001655 ! urogenital system development +relationship: part_of GO:0048546 ! digestive tract morphogenesis +created_by: bf +creation_date: 2011-05-06T01:54:35Z + +[Term] +id: GO:0035845 +name: photoreceptor cell outer segment organization +namespace: biological_process +def: "A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials." [ISBN:0824072820, PMID:14507858] +synonym: "photoreceptor cell outer segment organisation" EXACT [GOC:mah] +synonym: "photoreceptor outer segment organization" EXACT [GOC:bf] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0042461 ! photoreceptor cell development +created_by: bf +creation_date: 2011-05-10T10:44:09Z + +[Term] +id: GO:0035846 +name: oviduct epithelium development +namespace: biological_process +def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct] +synonym: "fallopian tube epithelium development" NARROW [GOC:yaf] +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0060066 ! oviduct development +created_by: bf +creation_date: 2011-05-10T10:53:05Z + +[Term] +id: GO:0035847 +name: uterine epithelium development +namespace: biological_process +def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf] +synonym: "uterus epithelial development" EXACT [GOC:yaf] +is_a: GO:0035846 ! oviduct epithelium development +relationship: part_of GO:0060065 ! uterus development +created_by: bf +creation_date: 2011-05-10T10:57:45Z + +[Term] +id: GO:0035848 +name: oviduct morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct] +synonym: "fallopian tube morphogenesis" NARROW [GOC:yaf] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0060066 ! oviduct development +created_by: bf +creation_date: 2011-05-10T11:01:20Z + +[Term] +id: GO:0035849 +name: nephric duct elongation +namespace: biological_process +def: "The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0072178 ! nephric duct morphogenesis +created_by: bf +creation_date: 2011-05-11T11:31:39Z + +[Term] +id: GO:0035850 +name: epithelial cell differentiation involved in kidney development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0061005 ! cell differentiation involved in kidney development +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0001822 ! kidney development +created_by: bf +creation_date: 2011-05-11T11:34:21Z + +[Term] +id: GO:0035851 +name: Krueppel-associated box domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors." [InterPro:IPR001909] +synonym: "KRAB domain binding" EXACT [InterPro:IPR001909] +synonym: "Krueppel-associated box binding" EXACT [InterPro:IPR001909] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2011-05-11T11:41:16Z + +[Term] +id: GO:0035852 +name: horizontal cell localization +namespace: biological_process +def: "Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina." [CL:0000745, GOC:bf, GOC:yaf, PMID:18094249] +synonym: "horizontal cell localisation" EXACT [GOC:mah] +synonym: "horizontal cell positioning" EXACT [PMID:18094249] +synonym: "laminar positioning of retinal horizontal cell" EXACT [PMID:18094249] +synonym: "retinal horizontal cell positioning" EXACT [PMID:18094249] +is_a: GO:0051674 ! localization of cell +relationship: part_of GO:0010842 ! retina layer formation +created_by: bf +creation_date: 2011-05-11T01:56:40Z + +[Term] +id: GO:0035853 +name: chromosome passenger complex localization to spindle midzone +namespace: biological_process +def: "A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:mah, GOC:vw, PMID:15296749] +synonym: "chromosomal passenger complex localization to spindle midzone" EXACT [GOC:bf] +synonym: "chromosome passenger complex localisation to spindle midzone" EXACT [GOC:bf] +synonym: "chromosome passenger complex localization to central spindle" EXACT [PMID:14528012] +synonym: "chromosome passenger complex localization to spindle equator" EXACT [GOC:bf] +synonym: "CPC complex localization to spindle midzone" EXACT [GOC:bf] +synonym: "CPC localization to spindle midzone" EXACT [GOC:bf] +is_a: GO:0034629 ! cellular protein-containing complex localization +is_a: GO:0044380 ! protein localization to cytoskeleton +created_by: bf +creation_date: 2011-05-13T01:19:51Z + +[Term] +id: GO:0035854 +name: eosinophil fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin." [CL:0000771, GOC:BHF, GOC:vk] +synonym: "eosinophil cell fate commitment" EXACT [GOC:bf] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0030222 ! eosinophil differentiation +created_by: bf +creation_date: 2011-05-13T01:23:28Z + +[Term] +id: GO:0035855 +name: megakaryocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] +synonym: "megakaryocyte cell development" EXACT [GOC:bf] +is_a: GO:0061515 ! myeloid cell development +is_a: GO:0098751 ! bone cell development +relationship: part_of GO:0030219 ! megakaryocyte differentiation +created_by: bf +creation_date: 2011-05-13T01:28:06Z + +[Term] +id: GO:0035857 +name: eosinophil fate specification +namespace: biological_process +def: "The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [CL:0000771, GOC:BHF, GOC:vk] +synonym: "eosinophil cell fate specification" EXACT [GOC:bf] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0035854 ! eosinophil fate commitment +created_by: bf +creation_date: 2011-05-17T10:42:54Z + +[Term] +id: GO:0035858 +name: eosinophil fate determination +namespace: biological_process +def: "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed." [CL:0000771, GOC:BHF, GOC:vk] +synonym: "eosinophil cell fate determination" EXACT [GOC:bf] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0035854 ! eosinophil fate commitment +created_by: bf +creation_date: 2011-05-17T10:43:35Z + +[Term] +id: GO:0035859 +name: Seh1-associated complex +namespace: cellular_component +def: "A protein complex that associates dynamically with the vacuolar membrane, and is proposed to have a role in membrane-associated trafficking or regulatory processes. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p." [GOC:jh, PMID:21454883, PMID:23974112] +synonym: "GATOR complex" EXACT [GOC:rb, PMID:23723238] +synonym: "SEA complex" EXACT [GOC:jh, PMID:21454883] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2011-05-17T10:59:50Z + +[Term] +id: GO:0035860 +name: glial cell-derived neurotrophic factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands." [GOC:yaf, PMID:12953054] +synonym: "GDNF receptor signaling pathway" EXACT [GOC:yaf] +synonym: "glial cell derived neurotrophic factor receptor signaling pathway" EXACT [GOC:bf] +synonym: "glial cell line-derived neurotrophic factor receptor signalling pathway" EXACT [GOC:yaf] +synonym: "glial cell-derived neurotrophic factor receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +created_by: bf +creation_date: 2011-05-17T11:01:33Z + +[Term] +id: GO:0035861 +name: site of double-strand break +namespace: cellular_component +def: "A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix." [GOC:bf, GOC:mah, GOC:vw, PMID:20096808, PMID:21035408] +synonym: "DNA damage foci" RELATED [GOC:vw] +synonym: "DNA damage focus" RELATED [GOC:mah, PMID:20096808, PMID:21035408] +synonym: "ionizing radiation-induced foci" RELATED [PMID:20096808, PMID:21035408] +synonym: "IRIF" RELATED [PMID:20096808, PMID:21035408] +synonym: "site of DSB" EXACT [PMID:21035408] +is_a: GO:0090734 ! site of DNA damage +created_by: bf +creation_date: 2011-05-17T03:04:42Z + +[Term] +id: GO:0035862 +name: dITP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position." [GOC:bf] +synonym: "2'-Deoxyinosine 5'-triphosphate metabolic process" EXACT [] +synonym: "2'-Deoxyinosine-5'-triphosphate metabolic process" EXACT [] +synonym: "deoxyinosine 5'-triphosphate metabolic process" EXACT [] +synonym: "deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) metabolic process" EXACT [GOC:dgf] +synonym: "dITP metabolism" EXACT [GOC:bf] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009215 ! purine deoxyribonucleoside triphosphate metabolic process +created_by: bf +creation_date: 2011-05-25T02:52:58Z + +[Term] +id: GO:0035863 +name: dITP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position." [GOC:dgf] +synonym: "2'-Deoxyinosine 5'-triphosphate catabolic process" EXACT [] +synonym: "2'-Deoxyinosine-5'-triphosphate catabolic process" EXACT [] +synonym: "deoxyinosine 5'-triphosphate catabolic process" EXACT [] +synonym: "deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process" EXACT [GOC:dgf] +synonym: "dITP breakdown" EXACT [GOC:bf] +synonym: "dITP catabolism" EXACT [GOC:bf] +synonym: "dITP degradation" EXACT [GOC:bf] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009217 ! purine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0035862 ! dITP metabolic process +created_by: bf +creation_date: 2011-05-25T02:55:21Z + +[Term] +id: GO:0035864 +name: response to potassium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus." [GOC:yaf] +synonym: "response to K+ ion" EXACT [GOC:bf] +synonym: "response to potassium" EXACT [GOC:bf] +is_a: GO:0010038 ! response to metal ion +created_by: bf +creation_date: 2011-05-25T02:58:45Z + +[Term] +id: GO:0035865 +name: cellular response to potassium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus." [GOC:yaf] +synonym: "cellular response to K+ ion" EXACT [GOC:bf] +synonym: "cellular response to potassium" EXACT [GOC:bf] +is_a: GO:0035864 ! response to potassium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: bf +creation_date: 2011-05-25T02:59:11Z + +[Term] +id: GO:0035866 +name: alphav-beta3 integrin-PKCalpha complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha." [GOC:BHF, GOC:ebc, PMID:16014375] +synonym: "alphav-beta3 integrin-PKCa complex" EXACT [GOC:ebc] +synonym: "alphav-beta3 integrin-protein kinase C alpha complex" EXACT [GOC:bf] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: bf +creation_date: 2011-05-25T03:03:59Z + +[Term] +id: GO:0035867 +name: alphav-beta3 integrin-IGF-1-IGF1R complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits." [GOC:BHF, GOC:ebc, PMID:19578119] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: bf +creation_date: 2011-05-25T03:06:30Z + +[Term] +id: GO:0035868 +name: alphav-beta3 integrin-HMGB1 complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein." [GOC:BHF, GOC:ebc, PMID:20826760] +synonym: "alphav-beta3 integrin-high mobility group box 1 complex" EXACT [GOC:bf] +synonym: "alphaV-beta3 integrin-HMGB1 complex" EXACT [GOC:ebc] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: bf +creation_date: 2011-05-25T03:07:24Z + +[Term] +id: GO:0035869 +name: ciliary transition zone +namespace: cellular_component +def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230] +comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone. +synonym: "cilial transition zone" EXACT [] +synonym: "cilium transition zone" EXACT [] +synonym: "connecting cilium" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium +created_by: bf +creation_date: 2011-05-25T03:09:58Z + +[Term] +id: GO:0035870 +name: dITP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dITP + H2O = dIMP + diphosphate." [GOC:dgf, PMID:21548881, RHEA:28342] +synonym: "2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity" EXACT [KEGG_REACTION:R03531] +synonym: "deoxyinosine triphosphate pyrophosphatase activity" EXACT [GOC:bf] +synonym: "dITP pyrophosphatase activity" EXACT [GOC:bf] +xref: EC:3.6.1.66 +xref: KEGG_REACTION:R03531 +xref: MetaCyc:RXN0-1602 +xref: Reactome:R-HSA-2509838 "ITPA hydrolyses dITP to dIMP" +xref: RHEA:28342 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2011-05-26T11:32:26Z + +[Term] +id: GO:0035871 +name: protein K11-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein." [GOC:sp, PMID:21596315] +synonym: "protein K11-linked deubiquitinylation" EXACT [GOC:bf] +synonym: "protein K11-linked deubiquitylation" EXACT [GOC:bf] +is_a: GO:0016579 ! protein deubiquitination +created_by: bf +creation_date: 2011-05-26T11:44:13Z + +[Term] +id: GO:0035872 +name: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process." [GOC:sj, PMID:18280719, Reactome:168643] +synonym: "NLR signaling pathway" EXACT [PMID:18280719] +synonym: "NOD-like receptor signaling pathway" RELATED [Wikipedia:NOD-like_receptor] +synonym: "nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway" EXACT [PMID:18280719] +synonym: "nucleotide-binding domain, leucine rich repeat containing receptor signal transduction" EXACT [GOC:bf] +synonym: "nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway" EXACT [GOC:bf] +synonym: "nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0030522 ! intracellular receptor signaling pathway +created_by: bf +creation_date: 2011-05-26T03:30:36Z + +[Term] +id: GO:0035873 +name: lactate transmembrane transport +namespace: biological_process +def: "The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:mcc, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "lactate membrane transport" EXACT [] +is_a: GO:0015727 ! lactate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: bf +creation_date: 2011-05-31T09:26:59Z + +[Term] +id: GO:0035874 +name: cellular response to copper ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions." [GOC:vw, PMID:16467469] +synonym: "cellular response to copper starvation" EXACT [GOC:bf] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0120126 ! response to copper ion starvation +created_by: bf +creation_date: 2011-05-31T09:28:47Z + +[Term] +id: GO:0035875 +name: maintenance of meiotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:vw, PMID:1708436] +synonym: "maintenance of centromeric meiotic sister chromatin cohesion" EXACT [GOC:bf] +synonym: "maintenance of meiotic sister chromatin cohesion at centromere" EXACT [GOC:bf] +synonym: "maintenance of sister chromatin cohesion at centromere at meiosis I" EXACT [GOC:bf] +is_a: GO:0034090 ! maintenance of meiotic sister chromatid cohesion +relationship: part_of GO:0051754 ! meiotic sister chromatid cohesion, centromeric +created_by: bf +creation_date: 2011-05-31T09:35:51Z + +[Term] +id: GO:0035876 +name: maintenance of meiotic sister chromatid cohesion, arms +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:vw, PMID:1708436] +synonym: "maintenance of meiotic sister chromatin cohesion along arms" EXACT [GOC:bf] +synonym: "maintenance of sister chromatin cohesion along arms at meiosis I" EXACT [GOC:bf] +is_a: GO:0034090 ! maintenance of meiotic sister chromatid cohesion +relationship: part_of GO:0051760 ! meiotic sister chromatid cohesion, arms +created_by: bf +creation_date: 2011-05-31T09:37:53Z + +[Term] +id: GO:0035877 +name: death effector domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD)." [GOC:ecd, InterPro:IPR001875] +comment: For binding to the death domain, consider instead the term 'death domain binding ; GO:0070513'. +synonym: "DED binding" EXACT [InterPro:IPR001875] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2011-05-31T09:40:46Z + +[Term] +id: GO:0035878 +name: nail development +namespace: biological_process +def: "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it." [GOC:bf, ISBN:0323025781, UBERON:0001705, Wikipedia:Nail_(anatomy)] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060173 ! limb development +created_by: bf +creation_date: 2011-05-31T02:30:34Z + +[Term] +id: GO:0035879 +name: plasma membrane lactate transport +namespace: biological_process +def: "The directed movement of lactate across a plasma membrane." [GOC:mcc] +synonym: "lactate plasma membrane transport" EXACT [GOC:bf] +is_a: GO:0035873 ! lactate transmembrane transport +created_by: bf +creation_date: 2011-05-31T02:54:32Z + +[Term] +id: GO:0035880 +name: embryonic nail plate morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits." [GOC:BHF, GOC:vk, ISBN:0323025781, PMID:11369996, UBERON:0008198, Wikipedia:Nail_(anatomy)] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0035878 ! nail development +relationship: part_of GO:0042733 ! embryonic digit morphogenesis +created_by: bf +creation_date: 2011-05-31T02:38:57Z + +[Term] +id: GO:0035881 +name: amacrine cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons." [CL:0000561, GOC:bf] +synonym: "amacrine neuron differentiation" EXACT [CL:0000561] +is_a: GO:0030182 ! neuron differentiation +relationship: part_of GO:0003407 ! neural retina development +created_by: bf +creation_date: 2011-06-06T11:32:50Z + +[Term] +id: GO:0035882 +name: defecation rhythm +namespace: biological_process +def: "The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated." [GOC:bf, GOC:kmv, PMID:7479775, PMID:8158250, PMID:9066270] +synonym: "defecation behavior" RELATED [PMID:7479775, PMID:9066270] +synonym: "defecation cycle" EXACT [PMID:8158250] +synonym: "defecation motor program" EXACT [GOC:kmv, PMID:9066270] +synonym: "DMP" EXACT [PMID:9066270] +is_a: GO:0007624 ! ultradian rhythm +relationship: part_of GO:0030421 ! defecation +created_by: bf +creation_date: 2011-06-06T11:36:35Z + +[Term] +id: GO:0035883 +name: enteroendocrine cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf] +is_a: GO:0002067 ! glandular epithelial cell differentiation +created_by: bf +creation_date: 2011-06-06T11:48:51Z + +[Term] +id: GO:0035884 +name: arabinan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues." [GOC:rs, ISBN:0198506732] +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0031221 ! arabinan metabolic process +created_by: bf +creation_date: 2011-06-08T11:01:14Z + +[Term] +id: GO:0035885 +name: exochitinase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain." [EC:3.2.1.-, GOC:bf, GOC:kah, GOC:pde, PMID:11468293, PMID:16298970, PMID:21390509] +xref: MetaCyc:RXN-12309 +is_a: GO:0004568 ! chitinase activity +created_by: bf +creation_date: 2011-06-08T11:13:58Z + +[Term] +id: GO:0035886 +name: vascular smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954] +synonym: "vascular associated smooth muscle cell differentiation" EXACT [CL:0000359] +synonym: "VSMC differentiation" EXACT [PMID:16151017] +is_a: GO:0051145 ! smooth muscle cell differentiation +relationship: part_of GO:0001944 ! vasculature development +created_by: bf +creation_date: 2011-06-08T11:23:52Z + +[Term] +id: GO:0035887 +name: aortic smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl] +is_a: GO:0035886 ! vascular smooth muscle cell differentiation +created_by: bf +creation_date: 2011-06-08T11:34:26Z + +[Term] +id: GO:0035888 +name: isoguanine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: isoguanine + H2O = xanthine + NH3." [EC:3.5.4.-, GOC:imk, PMID:21604715] +synonym: "2-hydroxyadenine deaminase activity" EXACT [PMID:14709079, PMID:8841637] +synonym: "2-oxoadenine deaminase activity" EXACT [PMID:14709079] +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity +created_by: bf +creation_date: 2011-06-14T02:15:53Z + +[Term] +id: GO:0035889 +name: otolith tethering +namespace: biological_process +def: "The attachment of a developing otolith to the kinocilia of tether cells in the inner ear." [GOC:dgh, PMID:14499652] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0048840 ! otolith development +created_by: bf +creation_date: 2011-06-14T02:28:14Z + +[Term] +id: GO:0035890 +name: exit from host +namespace: biological_process +def: "The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf] +synonym: "ejection from host" RELATED [GOC:bf] +is_a: GO:0052126 ! movement in host environment +created_by: bf +creation_date: 2011-06-15T02:08:03Z + +[Term] +id: GO:0035891 +name: exit from host cell +namespace: biological_process +def: "The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:rs, PMID:19325115] +synonym: "ejection from host cell" RELATED [PMID:19325115] +synonym: "host cell exit" EXACT [PMID:19325115] +is_a: GO:0035890 ! exit from host +created_by: bf +creation_date: 2011-06-15T02:09:28Z + +[Term] +id: GO:0035892 +name: modulation of platelet aggregation in other organism +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:bf, GOC:fj, PMID:15922770] +synonym: "modulation by organism of platelet aggregation in other organism" EXACT [GOC:bf] +synonym: "regulation of platelet aggregation in other organism" RELATED [GOC:bf] +is_a: GO:0035806 ! modulation of blood coagulation in other organism +is_a: GO:0044364 ! disruption of cells of other organism +is_a: GO:0090330 ! regulation of platelet aggregation +created_by: bf +creation_date: 2011-06-15T02:21:10Z + +[Term] +id: GO:0035893 +name: negative regulation of platelet aggregation in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism." [GOC:bf, GOC:fj, PMID:15922770] +synonym: "down-regulation of platelet aggregation in other organism" EXACT [GOC:bf] +synonym: "downregulation of platelet aggregation in other organism" EXACT [GOC:bf] +synonym: "inhibition of platelet aggregation in other organism" EXACT [GOC:bf] +synonym: "suppression of platelet aggregation in other organism" EXACT [GOC:bf] +is_a: GO:0035892 ! modulation of platelet aggregation in other organism +is_a: GO:0035899 ! negative regulation of blood coagulation in other organism +is_a: GO:0090331 ! negative regulation of platelet aggregation +created_by: bf +creation_date: 2011-06-15T02:24:43Z + +[Term] +id: GO:0035894 +name: positive regulation of platelet aggregation in other organism +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism." [GOC:bf, GOC:fj, PMID:11453648, PMID:18804547] +synonym: "up-regulation of platelet aggregation in other organism" RELATED [GOC:bf] +synonym: "upregulation of platelet aggregation in other organism" EXACT [GOC:bf] +is_a: GO:0035807 ! positive regulation of blood coagulation in other organism +is_a: GO:0035892 ! modulation of platelet aggregation in other organism +is_a: GO:1901731 ! positive regulation of platelet aggregation +created_by: bf +creation_date: 2011-06-15T02:28:46Z + +[Term] +id: GO:0035895 +name: modulation of mast cell degranulation in other organism +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell." [GOC:bf, GOC:fj, PMID:21549739] +synonym: "regulation of mast cell degranulation in other organism" EXACT [GOC:bf] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:0043304 ! regulation of mast cell degranulation +created_by: bf +creation_date: 2011-06-15T02:46:50Z + +[Term] +id: GO:0035896 +name: positive regulation of mast cell degranulation in other organism +namespace: biological_process +def: "Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism." [GOC:bf, GOC:fj] +synonym: "up-regulation of mast cell degranulation in other organism" RELATED [GOC:bf] +synonym: "upregulation of mast cell degranulation in other organism" EXACT [GOC:bf] +is_a: GO:0035895 ! modulation of mast cell degranulation in other organism +is_a: GO:0043306 ! positive regulation of mast cell degranulation +created_by: bf +creation_date: 2011-06-15T02:49:03Z + +[Term] +id: GO:0035897 +name: proteolysis in other organism +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds." [GOC:bf, GOC:fj, PMID:15922779] +is_a: GO:0006508 ! proteolysis +is_a: GO:0044033 ! multi-organism metabolic process +created_by: bf +creation_date: 2011-06-15T03:00:27Z + +[Term] +id: GO:0035898 +name: parathyroid hormone secretion +namespace: biological_process +def: "The regulated release of parathyroid hormone into the circulatory system." [GOC:cjm, PMID:12171519, PMID:21164021, PR:000013429] +synonym: "parathormone secretion" EXACT [PR:000013429] +synonym: "parathyrin secretion" EXACT [PR:000013429] +synonym: "PTH secretion" EXACT [PMID:12171519, PR:000013429] +is_a: GO:0060986 ! endocrine hormone secretion +created_by: bf +creation_date: 2011-06-22T09:28:54Z + +[Term] +id: GO:0035899 +name: negative regulation of blood coagulation in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot." [GOC:fj] +synonym: "down-regulation of blood coagulation in other organism" EXACT [GOC:bf] +synonym: "downregulation of blood coagulation in other organism" EXACT [GOC:bf] +synonym: "inhibition of blood coagulation in other organism" NARROW [GOC:bf] +synonym: "negative regulation of blood clotting in other organism" EXACT [GOC:bf] +synonym: "suppression of blood coagulation in other organism" EXACT [GOC:bf] +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:0035806 ! modulation of blood coagulation in other organism +created_by: bf +creation_date: 2011-06-22T09:17:54Z + +[Term] +id: GO:0035900 +name: response to isolation stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species." [GOC:bf, PMID:20203532] +synonym: "response to social isolation" EXACT [PMID:20203532] +is_a: GO:0006950 ! response to stress +created_by: bf +creation_date: 2011-06-22T09:39:57Z + +[Term] +id: GO:0035901 +name: cellular response to isolation stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species." [GOC:bf, PMID:20203532] +synonym: "cellular response to social isolation" EXACT [PMID:20203532] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0035900 ! response to isolation stress +created_by: bf +creation_date: 2011-06-22T09:43:34Z + +[Term] +id: GO:0035902 +name: response to immobilization stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile." [GOC:bf, PMID:17683801, PMID:19893991] +synonym: "response to immobilisation stress" EXACT [GOC:bf] +synonym: "response to restraint stress" RELATED [GOC:sl] +is_a: GO:0006950 ! response to stress +created_by: bf +creation_date: 2011-06-22T09:45:50Z + +[Term] +id: GO:0035903 +name: cellular response to immobilization stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile." [GOC:bf, PMID:17683801, PMID:19893991] +synonym: "cellular response to immobilisation stress" EXACT [GOC:bf] +synonym: "cellular response to restraint stress" RELATED [GOC:sl] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0035902 ! response to immobilization stress +created_by: bf +creation_date: 2011-06-22T09:47:44Z + +[Term] +id: GO:0035904 +name: aorta development +namespace: biological_process +def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] +is_a: GO:0060840 ! artery development +created_by: bf +creation_date: 2011-06-24T11:00:07Z + +[Term] +id: GO:0035905 +name: ascending aorta development +namespace: biological_process +def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035904 ! aorta development +created_by: bf +creation_date: 2011-06-24T11:02:01Z + +[Term] +id: GO:0035906 +name: descending aorta development +namespace: biological_process +def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035904 ! aorta development +created_by: bf +creation_date: 2011-06-24T11:05:22Z + +[Term] +id: GO:0035907 +name: dorsal aorta development +namespace: biological_process +def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] +is_a: GO:0035904 ! aorta development +created_by: bf +creation_date: 2011-06-24T11:07:01Z + +[Term] +id: GO:0035908 +name: ventral aorta development +namespace: biological_process +def: "The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0003085, Wikipedia:Aorta, ZFA:0000604] +is_a: GO:0035904 ! aorta development +created_by: bf +creation_date: 2011-06-24T11:08:49Z + +[Term] +id: GO:0035909 +name: aorta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] +is_a: GO:0048844 ! artery morphogenesis +relationship: part_of GO:0035904 ! aorta development +created_by: bf +creation_date: 2011-06-24T11:11:11Z + +[Term] +id: GO:0035910 +name: ascending aorta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0035905 ! ascending aorta development +relationship: part_of GO:0035909 ! aorta morphogenesis +created_by: bf +creation_date: 2011-06-24T11:14:52Z + +[Term] +id: GO:0035911 +name: descending aorta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0035906 ! descending aorta development +relationship: part_of GO:0035909 ! aorta morphogenesis +created_by: bf +creation_date: 2011-06-24T11:19:24Z + +[Term] +id: GO:0035912 +name: dorsal aorta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] +is_a: GO:0035909 ! aorta morphogenesis +relationship: part_of GO:0035907 ! dorsal aorta development +created_by: bf +creation_date: 2011-06-24T11:22:14Z + +[Term] +id: GO:0035913 +name: ventral aorta morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0003085, Wikipedia:Aorta, ZFA:0000604] +is_a: GO:0035909 ! aorta morphogenesis +relationship: part_of GO:0035908 ! ventral aorta development +created_by: bf +creation_date: 2011-06-24T11:24:36Z + +[Term] +id: GO:0035914 +name: skeletal muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007519 ! skeletal muscle tissue development +created_by: bf +creation_date: 2011-06-24T02:36:19Z + +[Term] +id: GO:0035915 +name: pore formation in membrane of other organism +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism." [GOC:bf, GOC:fj, PMID:21549739] +synonym: "pore biosynthesis in other organism" EXACT [GOC:bf] +synonym: "pore complex assembly in other organism" EXACT [] +synonym: "pore complex biogenesis in other organism" EXACT [GOC:bf] +synonym: "pore formation in other organism" EXACT [GOC:bf] +synonym: "pore-forming toxin activity" RELATED [GOC:bf] +is_a: GO:0051673 ! membrane disruption in other organism +created_by: bf +creation_date: 2011-07-01T11:45:01Z + +[Term] +id: GO:0035916 +name: modulation of calcium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism." [GOC:bf, GOC:fj, PMID:20920515] +is_a: GO:0044561 ! modulation of ion channel activity in other organism +created_by: bf +creation_date: 2011-07-01T11:51:38Z + +[Term] +id: GO:0035917 +name: negative regulation of calcium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism." [GOC:bf, GOC:fj, PMID:20920515] +synonym: "down-regulation of calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "downregulation of calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "inhibition of calcium channel activity in other organism" NARROW [GOC:bf] +is_a: GO:0035916 ! modulation of calcium channel activity in other organism +is_a: GO:0052204 ! negative regulation of molecular function in other organism involved in symbiotic interaction +created_by: bf +creation_date: 2011-07-01T11:52:55Z + +[Term] +id: GO:0035918 +name: negative regulation of voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515] +synonym: "down-regulation of voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "downregulation of voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "inhibition of voltage-gated calcium channel activity in other organism" NARROW [GOC:bf] +synonym: "negative regulation of voltage gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "negative regulation of voltage-dependent calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "negative regulation of voltage-sensitive calcium channel activity in other organism" EXACT [GOC:bf] +is_a: GO:0035917 ! negative regulation of calcium channel activity in other organism +created_by: bf +creation_date: 2011-07-01T11:54:43Z + +[Term] +id: GO:0035919 +name: negative regulation of low voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515] +synonym: "down-regulation of low voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "downregulation of low voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "inhibition of low voltage-gated calcium channel activity in other organism" NARROW [GOC:bf] +synonym: "negative regulation of low voltage gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "negative regulation of low voltage-dependent calcium channel activity in other organism" EXACT [GOC:bf] +is_a: GO:0035918 ! negative regulation of voltage-gated calcium channel activity in other organism +created_by: bf +creation_date: 2011-07-01T11:56:21Z + +[Term] +id: GO:0035920 +name: negative regulation of high voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded." [GOC:bf, GOC:fj, ISBN:0815340729, PMID:20920515] +synonym: "down-regulation of high voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "downregulation of high voltage-gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "inhibition of high voltage-gated calcium channel activity in other organism" NARROW [GOC:bf] +synonym: "negative regulation of high voltage gated calcium channel activity in other organism" EXACT [GOC:bf] +synonym: "negative regulation of high voltage-dependent calcium channel activity in other organism" EXACT [GOC:bf] +is_a: GO:0035918 ! negative regulation of voltage-gated calcium channel activity in other organism +created_by: bf +creation_date: 2011-07-01T12:00:23Z + +[Term] +id: GO:0035921 +name: desmosome disassembly +namespace: biological_process +def: "The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm." [GOC:BHF, GOC:vk, ISBN:0198506732, PMID:9182671] +synonym: "desmosome dissociation" EXACT [PMID:9182671] +is_a: GO:0002934 ! desmosome organization +is_a: GO:0150147 ! cell-cell junction disassembly +created_by: bf +creation_date: 2011-07-05T01:33:25Z + +[Term] +id: GO:0035922 +name: foramen ovale closure +namespace: biological_process +def: "The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow." [GOC:BHF, GOC:vk, PMID:19762328, UBERON:0004754, Wikipedia:Foramen_ovale_(heart)] +synonym: "foramen ovale of heart closure" EXACT [UBERON:0004754] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060411 ! cardiac septum morphogenesis +created_by: bf +creation_date: 2011-07-05T01:39:54Z + +[Term] +id: GO:0035923 +name: flurbiprofen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with flurbiprofen." [GOC:BHF, GOC:rl] +synonym: "2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: bf +creation_date: 2011-07-15T03:53:53Z + +[Term] +id: GO:0035924 +name: cellular response to vascular endothelial growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus." [GOC:BHF, GOC:rl, PMID:18440775] +synonym: "cellular response to vascular endothelial growth factor" EXACT [GOC:rl] +synonym: "cellular response to VEGF" EXACT [GOC:rl] +synonym: "cellular response to VEGFA" NARROW [GOC:rl] +synonym: "cellular response to VEGFB" NARROW [GOC:rl] +is_a: GO:0071363 ! cellular response to growth factor stimulus +created_by: bf +creation_date: 2011-07-15T04:03:29Z + +[Term] +id: GO:0035925 +name: mRNA 3'-UTR AU-rich region binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule." [GOC:vw] +synonym: "mRNA 3'-UTR adenylate/uridylate-rich element binding" EXACT [PMID:8578590] +is_a: GO:0003730 ! mRNA 3'-UTR binding +is_a: GO:0017091 ! AU-rich element binding +created_by: bf +creation_date: 2011-07-19T09:30:18Z + +[Term] +id: GO:0035926 +name: chemokine (C-C motif) ligand 2 secretion +namespace: biological_process +def: "The regulated release of chemokine (C-C motif) ligand 2 (CCL2) from a cell." [PMID:21501162] +synonym: "CCL2 secretion" EXACT [GOC:bf] +is_a: GO:0090195 ! chemokine secretion +relationship: part_of GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +created_by: bf +creation_date: 2011-07-19T09:33:54Z + +[Term] +id: GO:0035927 +name: RNA import into mitochondrion +namespace: biological_process +def: "The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol, into the mitochondrial matrix." [GOC:ans, PMID:20691904] +synonym: "cytoplasmic RNA import into mitochondrion" NARROW [GOC:ans] +synonym: "nuclear-encoded RNA import into mitochondrion" NARROW [GOC:bf] +is_a: GO:0050658 ! RNA transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: bf +creation_date: 2011-07-19T09:39:37Z + +[Term] +id: GO:0035928 +name: rRNA import into mitochondrion +namespace: biological_process +def: "The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol, into the mitochondrial matrix." [GOC:ans, PMID:20691904] +synonym: "cytoplasmic rRNA import into mitochondrion" NARROW [GOC:ans] +synonym: "nuclear-encoded rRNA import into mitochondrion" NARROW [GOC:bf] +is_a: GO:0035927 ! RNA import into mitochondrion +is_a: GO:0051029 ! rRNA transport +created_by: bf +creation_date: 2011-07-19T09:41:42Z + +[Term] +id: GO:0035929 +name: steroid hormone secretion +namespace: biological_process +def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl] +is_a: GO:0060986 ! endocrine hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-20T01:01:00Z + +[Term] +id: GO:0035930 +name: corticosteroid hormone secretion +namespace: biological_process +def: "The regulated release of any corticosteroid hormone into the circulatory system." [GOC:sl] +synonym: "corticosteroid secretion" BROAD [GOC:bf] +is_a: GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-20T01:03:22Z + +[Term] +id: GO:0035931 +name: mineralocorticoid secretion +namespace: biological_process +def: "The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." [GOC:sl] +is_a: GO:0035930 ! corticosteroid hormone secretion +created_by: bf +creation_date: 2011-07-20T01:04:59Z + +[Term] +id: GO:0035932 +name: aldosterone secretion +namespace: biological_process +def: "The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney." [GOC:sl] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0035931 ! mineralocorticoid secretion +created_by: bf +creation_date: 2011-07-20T01:06:24Z + +[Term] +id: GO:0035933 +name: glucocorticoid secretion +namespace: biological_process +def: "The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." [GOC:sl] +is_a: GO:0035930 ! corticosteroid hormone secretion +created_by: bf +creation_date: 2011-07-20T01:08:37Z + +[Term] +id: GO:0035934 +name: corticosterone secretion +namespace: biological_process +def: "The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands." [GOC:sl] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0035933 ! glucocorticoid secretion +created_by: bf +creation_date: 2011-07-20T01:09:31Z + +[Term] +id: GO:0035935 +name: androgen secretion +namespace: biological_process +def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl] +is_a: GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-20T01:11:31Z + +[Term] +id: GO:0035936 +name: testosterone secretion +namespace: biological_process +def: "The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5." [GOC:sl, PMID:12606499] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0046879 ! hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-20T01:13:13Z + +[Term] +id: GO:0035937 +name: estrogen secretion +namespace: biological_process +def: "The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals." [GOC:sl] +synonym: "oestrogen secretion" RELATED [] +is_a: GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-20T01:14:44Z + +[Term] +id: GO:0035938 +name: estradiol secretion +namespace: biological_process +def: "The regulated release of estradiol into the circulatory system." [GOC:sl, PMID:21632818] +synonym: "oestradiol secretion" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0046879 ! hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-20T01:16:45Z + +[Term] +id: GO:0035939 +name: microsatellite binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem." [GOC:yaf, PMID:21290414, SO:0000289] +synonym: "microsatellite DNA binding" EXACT [GOC:bf] +synonym: "variable number tandem repeat binding" EXACT [PMID:21290414] +synonym: "VNTR binding" EXACT [SO:0000289] +is_a: GO:0003696 ! satellite DNA binding +created_by: bf +creation_date: 2011-07-20T01:26:26Z + +[Term] +id: GO:0035940 +name: negative regulation of peptidase activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism." [GOC:klp, PMID:10595640] +synonym: "down regulation of peptidase activity in other organism" EXACT [GOC:bf] +synonym: "down-regulation of protease activity in other organism" NARROW [GOC:bf] +synonym: "downregulation of peptidase activity in other organism" EXACT [GOC:bf] +synonym: "inhibition of protease activity in other organism" NARROW [GOC:bf] +synonym: "negative regulation of protease activity in other organism" NARROW [GOC:bf] +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:0044362 ! negative regulation of molecular function in other organism +created_by: bf +creation_date: 2011-07-22T02:59:40Z + +[Term] +id: GO:0035941 +name: androstenedione secretion +namespace: biological_process +def: "The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system." [GOC:sl] +synonym: "androst-4-ene-3,17-dione secretion" EXACT [] +is_a: GO:0046879 ! hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-25T02:11:47Z + +[Term] +id: GO:0035942 +name: dehydroepiandrosterone secretion +namespace: biological_process +def: "The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system." [GOC:sl] +synonym: "3beta-hydroxyandrost-5-en-17-one secretion" EXACT [] +synonym: "dehydroisoandrosterone secretion" EXACT [] +synonym: "DHEA secretion" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0046879 ! hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-25T02:13:54Z + +[Term] +id: GO:0035943 +name: estrone secretion +namespace: biological_process +def: "The regulated release of estrone into the circulatory system." [GOC:sl, PMID:8395854] +synonym: "3-hydroxy-1,3,5(10)-estratrien-17-one secretion" EXACT [] +synonym: "folliculin secretion" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport +is_a: GO:0046879 ! hormone secretion +is_a: GO:0140353 ! lipid export from cell +created_by: bf +creation_date: 2011-07-25T02:18:40Z + +[Term] +id: GO:0035944 +name: perforin production +namespace: biological_process +def: "The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv, PR:000003466] +is_a: GO:0002440 ! production of molecular mediator of immune response +created_by: bf +creation_date: 2011-07-27T11:44:21Z + +[Term] +id: GO:0035945 +name: mitochondrial ncRNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion." [GOC:ans, PMID:19864255] +synonym: "mitochondrial aberrant ncRNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "mitochondrial ncRNA quality control" EXACT [GOC:dgf, GOC:krc] +synonym: "mitochondrial non-coding RNA surveillance" EXACT [GOC:bf] +is_a: GO:2000827 ! mitochondrial RNA surveillance +created_by: bf +creation_date: 2011-07-28T10:34:59Z + +[Term] +id: GO:0035946 +name: mitochondrial mRNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion." [GOC:ans, PMID:19864255] +synonym: "mitochondrial aberrant RNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "mitochondrial messenger RNA surveillance" EXACT [GOC:bf] +synonym: "mitochondrial mRNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:2000827 ! mitochondrial RNA surveillance +created_by: bf +creation_date: 2011-07-28T10:37:07Z + +[Term] +id: GO:0035947 +name: obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of gluconeogenesis by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035948 +name: obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17875938] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035949 +name: obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17875938] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of gluconeogenesis by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of gluconeogenesis by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of gluconeogenesis by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of gluconeogenesis by inhibition of transcription from RNA polymerase II promoter" NARROW [GOC:obol] +synonym: "positive regulation of gluconeogenesis by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthesis by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthesis by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthesis by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthesis by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthesis by negative regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of glucose biosynthetic process by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthetic process by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthetic process by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthetic process by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glucose biosynthetic process by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035950 +name: obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of oligopeptide transport by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035951 +name: obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035952 +name: obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter" NARROW [GOC:obol] +synonym: "negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035953 +name: obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:17005992] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of dipeptide transport by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035954 +name: obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of dipeptide transport by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of dipeptide transport by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of dipeptide transport by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of dipeptide transport by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of dipeptide transport by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of dipeptide transport by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035955 +name: obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:10850718, PMID:17005992, PMID:9427760] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of dipeptide transport by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of dipeptide transport by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of dipeptide transport by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of dipeptide transport by inhibition of transcription from RNA polymerase II promoter" NARROW [GOC:obol] +synonym: "negative regulation of dipeptide transport by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035956 +name: obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:9342405] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of starch breakdown by regulation of transcription from Pol II promoter" EXACT [GGOC:obol] +synonym: "regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of starch catabolic process by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of starch catabolism by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of starch degradation by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of starch degradation by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035957 +name: obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of starch breakdown by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch catabolic process by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch catabolism by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch degradation by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of starch degradation by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035958 +name: obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of glyoxylate bypass by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of glyoxylate bypass by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "regulation of glyoxylate cycle by regulation of transcription from Pol II promoter" RELATED [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035959 +name: obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11024040, PMID:17875938, PMID:19686338] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of glyoxylate bypass by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate bypass by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate bypass by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate bypass by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate bypass by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of glyoxylate cycle by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035960 +name: obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229, PMID:16055745] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of ergosterol anabolism by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of ergosterol anabolism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "regulation of ergosterol biosynthesis by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of ergosterol biosynthesis by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "regulation of ergosterol biosynthetic process by regulation of transcription from Pol II promoter" RELATED [GOC:obol] +synonym: "regulation of ergosterol formation by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of ergosterol formation by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "regulation of ergosterol synthesis by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of ergosterol synthesis by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035961 +name: obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:obol] +synonym: "positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035962 +name: response to interleukin-13 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus." [GOC:sjw, PMID:20100461] +synonym: "response to IL-13" EXACT [GOC:bf] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2011-08-01T11:29:02Z + +[Term] +id: GO:0035963 +name: cellular response to interleukin-13 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus." [GOC:sjw, PMID:20100461] +synonym: "cellular response to IL-13" EXACT [GOC:bf] +is_a: GO:0035962 ! response to interleukin-13 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2011-08-01T11:29:42Z + +[Term] +id: GO:0035964 +name: COPI-coated vesicle budding +namespace: biological_process +def: "The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle." [GOC:br, PMID:10052452, PMID:17041781] +synonym: "COPI vesicle budding" EXACT [PMID:17041781] +is_a: GO:0048194 ! Golgi vesicle budding +relationship: part_of GO:0048199 ! vesicle targeting, to, from or within Golgi +created_by: bf +creation_date: 2011-08-01T11:32:23Z + +[Term] +id: GO:0035965 +name: cardiolipin acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids." [GOC:bf, GOC:rb, PMID:19244244] +synonym: "cardiolipin acyl-chain remodelling" EXACT [GOC:bf] +synonym: "cardiolipin maturation" BROAD [GOC:rb] +synonym: "diphosphatidylglycerol remodeling" RELATED [] +is_a: GO:0032048 ! cardiolipin metabolic process +created_by: bf +creation_date: 2011-08-03T11:17:49Z + +[Term] +id: GO:0035966 +name: response to topologically incorrect protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." [GOC:bf] +synonym: "response to misfolded or unfolded protein" RELATED [GOC:bf] +is_a: GO:0006950 ! response to stress +is_a: GO:0010033 ! response to organic substance +created_by: bf +creation_date: 2011-08-03T11:43:12Z + +[Term] +id: GO:0035967 +name: cellular response to topologically incorrect protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." [GOC:bf] +synonym: "cellular response to misfolded or unfolded protein" RELATED [GOC:bf] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0035966 ! response to topologically incorrect protein +is_a: GO:0071310 ! cellular response to organic substance +created_by: bf +creation_date: 2011-08-03T11:44:50Z + +[Term] +id: GO:0035968 +name: obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:12077145] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of sterol import by regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "regulation of sterol influx by regulation of transcription from Pol II promoter" EXACT [GOC:bf] +synonym: "regulation of sterol influx by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:bf] +synonym: "regulation of sterol uptake by regulation of transcription from Pol II promoter" EXACT [GOC:bf] +synonym: "regulation of sterol uptake by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035969 +name: obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:11533229] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of sterol import by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol import by positive regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol import by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol import by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol import by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0035970 +name: peptidyl-threonine dephosphorylation +namespace: biological_process +def: "The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine." [GOC:bf] +is_a: GO:0006470 ! protein dephosphorylation +created_by: bf +creation_date: 2011-08-08T02:57:11Z + +[Term] +id: GO:0035971 +name: peptidyl-histidine dephosphorylation +namespace: biological_process +def: "The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine." [GOC:BHF, GOC:vk, PMID:12383260] +is_a: GO:0006470 ! protein dephosphorylation +created_by: bf +creation_date: 2011-08-08T03:26:02Z + +[Term] +id: GO:0035973 +name: aggrephagy +namespace: biological_process +alt_id: GO:0035972 +def: "Selective degradation of protein aggregates by macroautophagy." [GOC:autophagy, GOC:kmv, PMID:18508269, PMID:25062811] +is_a: GO:0061912 ! selective autophagy +created_by: bf +creation_date: 2011-08-09T09:53:40Z + +[Term] +id: GO:0035974 +name: meiotic spindle pole body +namespace: cellular_component +def: "The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome." [GOC:vw, PMID:21775631] +is_a: GO:0005816 ! spindle pole body +created_by: bf +creation_date: 2011-08-16T11:37:59Z + +[Term] +id: GO:0035975 +name: carbamoyl phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [GOC:yaf, UniPathway:UPA00996] +synonym: "carbamoyl phosphate breakdown" EXACT [GOC:bf] +synonym: "carbamoyl phosphate catabolism" EXACT [GOC:bf] +synonym: "carbamoyl phosphate degradation" EXACT [GOC:bf] +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0070408 ! carbamoyl phosphate metabolic process +created_by: bf +creation_date: 2011-08-16T11:41:13Z + +[Term] +id: GO:0035976 +name: transcription factor AP-1 complex +namespace: cellular_component +def: "A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes." [GOC:bf, GOC:BHF, GOC:rl, PMID:20060892, PMID:9069263, Wikipedia:AP-1_transcription_factor] +synonym: "Activating protein 1 complex" EXACT [GOC:rl] +synonym: "AP-1 complex" EXACT [GOC:rl] +synonym: "AP1 complex" EXACT [GOC:rl] +synonym: "transcription factor AP1 complex" EXACT [GOC:rl] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: bf +creation_date: 2011-08-17T10:57:51Z + +[Term] +id: GO:0035977 +name: protein deglycosylation involved in glycoprotein catabolic process +namespace: biological_process +def: "The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein." [GOC:bf, GOC:vw] +is_a: GO:0006517 ! protein deglycosylation +intersection_of: GO:0006517 ! protein deglycosylation +intersection_of: part_of GO:0006516 ! glycoprotein catabolic process +relationship: part_of GO:0006516 ! glycoprotein catabolic process +created_by: bf +creation_date: 2011-08-18T10:31:23Z + +[Term] +id: GO:0035978 +name: histone H2A-S139 phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone." [GOC:yaf, PMID:16061642] +comment: Residue 1 of histone H2AX is taken as the first residue following removal of the initiating Methionine (Met). +synonym: "histone H2A.x phosphorylation at S139" NARROW [GOC:bf, PMID:16061642] +is_a: GO:0035404 ! histone-serine phosphorylation +is_a: GO:1990164 ! histone H2A phosphorylation +created_by: bf +creation_date: 2011-08-22T11:34:09Z + +[Term] +id: GO:0035979 +name: histone kinase activity (H2A-S139 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A." [GOC:yaf, PMID:16061642] +comment: Residue 1 of histone H2A is taken as the first residue following removal of the initiating Methionine (Met). +synonym: "histone kinase activity (H2A.x-S139 specific)" NARROW [GOC:bf, PMID:16061642] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0035978 ! histone H2A-S139 phosphorylation +created_by: bf +creation_date: 2011-08-22T01:13:34Z + +[Term] +id: GO:0035980 +name: obsolete invasive growth in response to nitrogen limitation +namespace: biological_process +def: "OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen." [GOC:vw] +comment: This term was made obsolete because the GO term 'pseudohyphal growth ; GO:0007124' describes growth under nitrogen-limiting conditions. +synonym: "invasive growth in response to nitrogen limitation" EXACT [] +is_obsolete: true +consider: GO:0007124 +created_by: bf +creation_date: 2011-08-22T01:20:39Z + +[Term] +id: GO:0035981 +name: tongue muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell." [CL:0002673, GOC:yaf, PMID:3393851] +is_a: GO:0098528 ! skeletal muscle fiber differentiation +created_by: bf +creation_date: 2011-08-22T01:35:16Z + +[Term] +id: GO:0035982 +name: obsolete age-dependent behavioral decline +namespace: biological_process +def: "OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory." [GOC:kmv, PMID:20523893] +comment: This term was made obsolete because it describes a phenotype. +synonym: "age-dependent behavioural decline" EXACT [GOC:bf] +synonym: "age-related behavioral decline" EXACT [GOC:kmv] +synonym: "behavioral aging" EXACT [GOC:kmv] +is_obsolete: true +replaced_by: GO:0090647 +created_by: bf +creation_date: 2011-08-23T01:30:55Z + +[Term] +id: GO:0035983 +name: response to trichostatin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus." [GOC:yaf, PMID:20181743] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2011-08-23T01:48:01Z + +[Term] +id: GO:0035984 +name: cellular response to trichostatin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus." [GOC:yaf, PMID:20181743] +is_a: GO:0035983 ! response to trichostatin A +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: bf +creation_date: 2011-08-23T01:48:43Z + +[Term] +id: GO:0035985 +name: senescence-associated heterochromatin focus +namespace: cellular_component +def: "A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes." [GOC:yaf, PMID:15621527, PMID:21248468] +synonym: "SAHF" EXACT [GOC:yaf] +synonym: "senescence-associated heterochromatin foci" EXACT [PMID:15621527, PMID:21248468] +is_a: GO:0000792 ! heterochromatin +created_by: bf +creation_date: 2011-08-25T04:36:40Z + +[Term] +id: GO:0035986 +name: senescence-associated heterochromatin focus assembly +namespace: biological_process +def: "The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes." [GOC:yaf, PMID:15621527, PMID:21248468] +synonym: "SAHF formation" EXACT [GOC:yaf] +synonym: "senescence-associated heterochromatin foci formation" EXACT [GOC:yaf] +synonym: "senescence-associated heterochromatin focus formation" EXACT [] +is_a: GO:0031507 ! heterochromatin assembly +created_by: bf +creation_date: 2011-08-25T04:43:56Z + +[Term] +id: GO:0035987 +name: endodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332] +synonym: "endoderm cell differentiation" EXACT [CL:0000223] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001706 ! endoderm formation +created_by: bf +creation_date: 2011-08-25T04:50:36Z + +[Term] +id: GO:0035988 +name: chondrocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:yaf, PMID:21484705] +synonym: "cartilage cell proliferation" EXACT [CL:0000138] +synonym: "chondrocyte cell proliferation" EXACT [GOC:bf] +is_a: GO:0008283 ! cell population proliferation +created_by: bf +creation_date: 2011-08-25T04:53:40Z + +[Term] +id: GO:0035989 +name: tendon development +namespace: biological_process +def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043] +synonym: "sinew development" RELATED [UBERON:0000043] +is_a: GO:0061448 ! connective tissue development +created_by: bf +creation_date: 2011-08-26T04:14:30Z + +[Term] +id: GO:0035990 +name: tendon cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance." [CL:0000388, GOC:yaf, PMID:21412429] +synonym: "muscle attachment cell differentiation" EXACT [CL:0000388] +synonym: "tenocyte differentiation" RELATED [CL:0000388] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0035992 ! tendon formation +created_by: bf +creation_date: 2011-08-26T04:16:06Z + +[Term] +id: GO:0035991 +name: nitric oxide sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO)." [GOC:kmv, PMID:21491957] +synonym: "NO sensor activity" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0070026 ! nitric oxide binding +is_a: GO:0140299 ! small molecule sensor activity +relationship: part_of GO:0071731 ! response to nitric oxide +created_by: bf +creation_date: 2011-08-26T04:32:16Z + +[Term] +id: GO:0035992 +name: tendon formation +namespace: biological_process +def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035989 ! tendon development +created_by: bf +creation_date: 2011-08-30T01:35:10Z + +[Term] +id: GO:0035993 +name: deltoid tuberosity development +namespace: biological_process +def: "The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase." [GOC:yaf, PMID:17567668, UBERON:0002498, Wikipedia:Deltoid_tuberosity] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060173 ! limb development +relationship: part_of GO:0060348 ! bone development +created_by: bf +creation_date: 2011-08-30T01:46:53Z + +[Term] +id: GO:0035994 +name: response to muscle stretch +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length." [GOC:BHF, GOC:vk, PMID:14583192] +is_a: GO:0009612 ! response to mechanical stimulus +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2011-08-30T01:52:31Z + +[Term] +id: GO:0035995 +name: detection of muscle stretch +namespace: biological_process +def: "The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal." [PMID:14583192] +is_a: GO:0035994 ! response to muscle stretch +is_a: GO:0050982 ! detection of mechanical stimulus +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2011-08-30T01:53:35Z + +[Term] +id: GO:0035996 +name: rhabdomere microvillus +namespace: cellular_component +def: "Thin cylindrical membrane-covered projection on the surface of a rhabdomere." [GOC:bf, GOC:sart, PMID:14744998] +is_a: GO:0005902 ! microvillus +relationship: part_of GO:0016028 ! rhabdomere +created_by: bf +creation_date: 2011-09-01T02:18:30Z + +[Term] +id: GO:0035997 +name: rhabdomere microvillus membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a microvillus of a rhabdomere." [GOC:bf, GOC:sart, PMID:14744998] +is_a: GO:0031528 ! microvillus membrane +relationship: part_of GO:0033583 ! rhabdomere membrane +relationship: part_of GO:0035996 ! rhabdomere microvillus +created_by: bf +creation_date: 2011-09-01T02:24:20Z + +[Term] +id: GO:0035998 +name: 7,8-dihydroneopterin 3'-triphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate." [GOC:yaf, UniPathway:UPA00848] +synonym: "7,8-dihydroneopterin 3'-triphosphate anabolism" EXACT [GOC:bf] +synonym: "7,8-dihydroneopterin 3'-triphosphate biosynthesis" EXACT [GOC:bf] +synonym: "7,8-dihydroneopterin 3'-triphosphate formation" EXACT [GOC:bf] +synonym: "7,8-dihydroneopterin 3'-triphosphate synthesis" EXACT [GOC:bf] +xref: UniPathway:UPA00848 +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0051066 ! dihydrobiopterin metabolic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +created_by: bf +creation_date: 2011-09-02T01:15:35Z + +[Term] +id: GO:0035999 +name: tetrahydrofolate interconversion +namespace: biological_process +def: "The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules." [GOC:yaf, PMID:1825999, UniPathway:UPA00193] +xref: MetaCyc:PWY-2201 +xref: UniPathway:UPA00193 +is_a: GO:0006730 ! one-carbon metabolic process +is_a: GO:0046653 ! tetrahydrofolate metabolic process +created_by: bf +creation_date: 2011-09-02T01:35:49Z + +[Term] +id: GO:0036000 +name: mucocyst +namespace: cellular_component +def: "A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion." [GOC:mag, PMID:10723937, PMID:4629881] +is_a: GO:0030141 ! secretory granule +created_by: bf +creation_date: 2011-09-06T01:32:17Z + +[Term] +id: GO:0036001 +name: 'de novo' pyridoxal 5'-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components." [GOC:bf, GOC:yaf, MetaCyc:PYRIDOXSYN-PWY] +synonym: "'de novo' PLP biosynthesis" EXACT [MetaCyc:PYRIDOXSYN-PWY] +synonym: "'de novo' pyridoxal 5'-phosphate anabolism" EXACT [GOC:bf] +synonym: "'de novo' pyridoxal 5'-phosphate biosynthesis" EXACT [GOC:bf] +synonym: "'de novo' pyridoxal 5'-phosphate formation" EXACT [GOC:bf] +synonym: "'de novo' pyridoxal 5'-phosphate synthesis" EXACT [GOC:bf] +synonym: "'de novo' pyridoxal phosphate biosynthetic process" BROAD [GOC:bf] +xref: MetaCyc:PYRIDOXSYN-PWY +is_a: GO:0042823 ! pyridoxal phosphate biosynthetic process +created_by: bf +creation_date: 2011-09-06T02:04:53Z + +[Term] +id: GO:0036002 +name: pre-mRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule." [GOC:bf, GOC:kmv, PMID:21901112, SO:0000120] +synonym: "protein-coding primary transcript binding" RELATED [SO:0000120] +is_a: GO:0003723 ! RNA binding +created_by: bf +creation_date: 2011-09-16T10:23:37Z + +[Term] +id: GO:0036003 +name: positive regulation of transcription from RNA polymerase II promoter in response to stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mcc] +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +created_by: bf +creation_date: 2011-09-19T03:00:18Z + +[Term] +id: GO:0036004 +name: GAF domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the GAF domain of a protein." [GOC:yaf, InterPro:IPR003018] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2011-09-20T04:20:42Z + +[Term] +id: GO:0036005 +name: response to macrophage colony-stimulating factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus." [GOC:yaf, PMID:14687666] +synonym: "response to M-CSF" EXACT [GOC:bf, PMID:14687666] +synonym: "response to macrophage colony-stimulating factor" EXACT [GOC:bf] +synonym: "response to macrophage colony-stimulating factor stimulus" EXACT [GOC:dos] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2011-09-20T04:22:03Z + +[Term] +id: GO:0036006 +name: cellular response to macrophage colony-stimulating factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus." [GOC:yaf, PMID:14687666] +synonym: "cellular response to M-CSF stimulus" EXACT [GOC:bf, PMID:14687666] +synonym: "cellular response to macrophage colony-stimulating factor" EXACT [GOC:bf] +is_a: GO:0036005 ! response to macrophage colony-stimulating factor +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2011-09-20T04:23:19Z + +[Term] +id: GO:0036007 +name: scintillon +namespace: cellular_component +def: "A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen." [GOC:mag, GOC:pr, PMID:4501583, PMID:5642469] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2011-09-21T03:04:02Z + +[Term] +id: GO:0036008 +name: sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate." [GOC:bf, GOC:dgf, MetaCyc:SUCUTIL-PWY] +xref: MetaCyc:SUCUTIL-PWY +is_a: GO:0005987 ! sucrose catabolic process +is_a: GO:0006002 ! fructose 6-phosphate metabolic process +is_a: GO:0051156 ! glucose 6-phosphate metabolic process +relationship: has_part GO:0008865 ! fructokinase activity +relationship: has_part GO:0050307 ! sucrose-phosphate phosphatase activity +created_by: bf +creation_date: 2011-09-23T10:34:08Z + +[Term] +id: GO:0036009 +name: protein-glutamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine." [GOC:imk, PMID:11847124] +xref: Reactome:R-HSA-6800138 "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008276 ! protein methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: bf +creation_date: 2011-10-03T02:27:05Z + +[Term] +id: GO:0036010 +name: protein localization to endosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an endosome." [GOC:yaf] +synonym: "protein localisation in endosome" EXACT [GOC:bf] +synonym: "protein localization in endosome" EXACT [] +is_a: GO:0033365 ! protein localization to organelle +created_by: bf +creation_date: 2011-10-06T02:42:18Z + +[Term] +id: GO:0036011 +name: imaginal disc-derived leg segmentation +namespace: biological_process +def: "Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint." [GOC:bf] +is_a: GO:0035285 ! appendage segmentation +relationship: part_of GO:0007480 ! imaginal disc-derived leg morphogenesis +created_by: bf +creation_date: 2011-10-07T04:37:17Z + +[Term] +id: GO:0036012 +name: cyanelle inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma." [GOC:aa, PMID:18976493] +synonym: "cyanelle inner envelope membrane" EXACT [PMID:18976493] +is_a: GO:0009528 ! plastid inner membrane +is_a: GO:0033113 ! cyanelle membrane +created_by: bf +creation_date: 2011-10-10T01:48:56Z + +[Term] +id: GO:0036013 +name: cyanelle outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope." [GOC:aa] +is_a: GO:0009527 ! plastid outer membrane +is_a: GO:0033113 ! cyanelle membrane +created_by: bf +creation_date: 2011-10-10T01:50:56Z + +[Term] +id: GO:0036014 +name: cyanelle intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer." [GOC:aa] +synonym: "cyanelle envelope lumen" EXACT [GOC:bf] +synonym: "cyanelle periplasm" EXACT [PMID:18976493] +is_a: GO:0009529 ! plastid intermembrane space +relationship: part_of GO:0033112 ! cyanelle envelope +created_by: bf +creation_date: 2011-10-10T02:12:28Z + +[Term] +id: GO:0036015 +name: response to interleukin-3 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus." [GOC:yaf, PR:000001387] +synonym: "response to IL-3" EXACT [GOC:bf] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2011-10-12T10:08:26Z + +[Term] +id: GO:0036016 +name: cellular response to interleukin-3 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus." [GOC:yaf, PR:000001387] +synonym: "cellular response to IL-3" EXACT [GOC:bf] +is_a: GO:0036015 ! response to interleukin-3 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2011-10-12T10:09:10Z + +[Term] +id: GO:0036017 +name: response to erythropoietin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis." [GOC:yaf, PR:000007141] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2011-10-12T10:11:04Z + +[Term] +id: GO:0036018 +name: cellular response to erythropoietin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus." [GOC:yaf, PR:000007141] +is_a: GO:0036017 ! response to erythropoietin +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2011-10-12T10:12:18Z + +[Term] +id: GO:0036019 +name: endolysosome +namespace: cellular_component +def: "An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place." [GOC:pde, PMID:21878991] +is_a: GO:0005764 ! lysosome +is_a: GO:0005768 ! endosome +created_by: bf +creation_date: 2011-10-13T02:35:13Z + +[Term] +id: GO:0036020 +name: endolysosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome." [GOC:pde] +synonym: "endolysosomal membrane" EXACT [GOC:bf] +is_a: GO:0005765 ! lysosomal membrane +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0036019 ! endolysosome +created_by: bf +creation_date: 2011-10-13T04:32:00Z + +[Term] +id: GO:0036021 +name: endolysosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome." [GOC:pde] +synonym: "endolysosomal lumen" EXACT [GOC:bf] +is_a: GO:0031904 ! endosome lumen +is_a: GO:0043202 ! lysosomal lumen +relationship: part_of GO:0036019 ! endolysosome +created_by: bf +creation_date: 2011-10-13T04:32:31Z + +[Term] +id: GO:0036022 +name: limb joint morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner." [GOC:bf] +synonym: "knee morphogenesis" NARROW [GOC:bf] +synonym: "leg joint morphogenesis" NARROW [GOC:bf] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0035108 ! limb morphogenesis +created_by: bf +creation_date: 2011-10-13T04:52:59Z + +[Term] +id: GO:0036023 +name: embryonic skeletal limb joint morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb." [GOC:bf, Wikipedia:Joint] +is_a: GO:0036022 ! limb joint morphogenesis +is_a: GO:0060272 ! embryonic skeletal joint morphogenesis +relationship: part_of GO:0030326 ! embryonic limb morphogenesis +created_by: bf +creation_date: 2011-10-13T04:57:39Z + +[Term] +id: GO:0036024 +name: protein C inhibitor-TMPRSS7 complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7." [GOC:ans, PMID:15853774] +synonym: "PCI-TMPRSS7 complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-TMPRSS7 complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-matriptase-3 complex" EXACT [PMID:15853774, PR:000016461] +synonym: "protein C inhibitor-transmembrane protease serine 7 complex" EXACT [PR:000016461] +synonym: "serpin A5-TMPRSS7 complex" EXACT [PR:000014685] +synonym: "SERPINA5-TMPRSS7 complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T01:25:06Z + +[Term] +id: GO:0036025 +name: protein C inhibitor-TMPRSS11E complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E." [GOC:ans, PMID:15328353] +synonym: "PCI-TMPRSS11E complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-TMPRSS11E complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-transmembrane protease serine 11E complex" EXACT [PR:000016451] +synonym: "serpin A5-TMPRSS11E complex" EXACT [PR:000014685] +synonym: "SERPINA5-TMPRSS11E complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T01:29:08Z + +[Term] +id: GO:0036026 +name: protein C inhibitor-PLAT complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator." [GOC:ans, PMID:10340997] +synonym: "PCI-PLAT complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-PLAT complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-tissue-type plasminogen activator complex" EXACT [PMID:10340997, PR:000012825] +synonym: "protein C inhibitor-tPA complex" EXACT [PMID:10340997, PR:000012825] +synonym: "serpin A5-PLAT complex" EXACT [PR:000014685] +synonym: "SERPINA5-PLAT complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T01:30:56Z + +[Term] +id: GO:0036027 +name: protein C inhibitor-PLAU complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator." [GOC:ans, PMID:10340997, PMID:3501295, PMID:8536714] +synonym: "PCI-PLAU complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-PLAU complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-U-plasminogen activator complex" EXACT [PR:000012826] +synonym: "protein C inhibitor-uPA complex" EXACT [PR:000012826] +synonym: "protein C inhibitor-urokinase-type plasminogen activator complex" EXACT [PR:000012826] +synonym: "serpin A5-PLAU complex" EXACT [PR:000014685] +synonym: "SERPINA5-PLAU complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T01:37:03Z + +[Term] +id: GO:0036028 +name: protein C inhibitor-thrombin complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin." [GOC:ans, PMID:6323392] +synonym: "PCI-thrombin complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-thrombin complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-coagulation factor II complex" EXACT [PR:000007299] +synonym: "protein C inhibitor-F2 complex" EXACT [PR:000007299] +synonym: "serpin A5-thrombin complex" EXACT [PR:000014685] +synonym: "SERPINA5-thrombin complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T01:40:18Z + +[Term] +id: GO:0036029 +name: protein C inhibitor-KLK3 complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen." [GOC:ans, PMID:1725227] +synonym: "PCI-KLK3 complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-KLK3 complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-kallikrein-3 complex" EXACT [PR:000003015] +synonym: "protein C inhibitor-prostate-specific antigen complex" EXACT [PR:000003015] +synonym: "serpin A5-KLK3 complex" EXACT [PR:000014685] +synonym: "SERPINA5-KLK3 complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T02:01:33Z + +[Term] +id: GO:0036030 +name: protein C inhibitor-plasma kallikrein complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein." [GOC:ans, PMID:2844223, PMID:8536714] +synonym: "PCI-plasma kallikrein complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-plasma kallikrein complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-KLKB1 complex" EXACT [PR:000009420] +synonym: "serpin A5-plasma kallikrein complex" EXACT [PR:000014685] +synonym: "SERPINA5-plasma kallikrein complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: bf +creation_date: 2011-10-19T02:05:46Z + +[Term] +id: GO:0036031 +name: recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex +namespace: biological_process +def: "The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript." [GOC:bf, GOC:rb, PMID:10594013] +synonym: "capping enzyme targeting to RNA polymerase II" EXACT [PMID:10594013] +synonym: "recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex" EXACT [GOC:bf] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0006370 ! 7-methylguanosine mRNA capping +created_by: bf +creation_date: 2011-10-24T10:56:46Z + +[Term] +id: GO:0036032 +name: neural crest cell delamination +namespace: biological_process +def: "The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube." [CL:0000333, PMID:17076275] +synonym: "neural crest cell emigration" EXACT [PMID:17076275] +synonym: "neural crest cell individualization" EXACT [PMID:17076275] +synonym: "neural crest cell segregation" RELATED [PMID:17076275] +is_a: GO:0060232 ! delamination +created_by: bf +creation_date: 2011-10-31T03:50:30Z + +[Term] +id: GO:0036033 +name: mediator complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins." [GOC:yaf, PMID:18391015] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2011-10-31T05:09:12Z + +[Term] +id: GO:0036034 +name: mediator complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins." [GOC:yaf, PMID:17641689] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: bf +creation_date: 2011-10-31T05:18:11Z + +[Term] +id: GO:0036035 +name: osteoclast development +namespace: biological_process +def: "The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." [CL:0000092, GOC:bf, GOC:yaf] +synonym: "osteoclast cell development" EXACT [GOC:bf] +is_a: GO:0061515 ! myeloid cell development +is_a: GO:0098751 ! bone cell development +relationship: part_of GO:0030316 ! osteoclast differentiation +created_by: bf +creation_date: 2011-11-02T05:20:35Z + +[Term] +id: GO:0036036 +name: cardiac neural crest cell delamination +namespace: biological_process +def: "The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube." [GOC:hjd, PMID:17076275, PMID:18539270, PMID:20490374] +is_a: GO:0036032 ! neural crest cell delamination +created_by: bf +creation_date: 2011-11-02T05:23:29Z + +[Term] +id: GO:0036037 +name: CD8-positive, alpha-beta T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [CL:0000625, GOC:yaf] +is_a: GO:0046631 ! alpha-beta T cell activation +created_by: bf +creation_date: 2011-11-03T10:34:12Z + +[Term] +id: GO:0036038 +name: MKS complex +namespace: cellular_component +def: "A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane." [GOC:cilia, GOC:sp, PMID:21422230, PMID:21565611, PMID:21725307, PMID:22179047, PMID:25869670, PMID:26595381, PMID:26982032] +comment: Although there is some evidence, it is still unclear if the MKS and NPHP complexes are constituents parts of the Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the membrane and axoneme. +synonym: "B9 complex" NARROW [] +synonym: "MKS module" EXACT [] +synonym: "TCTN-B9D complex" BROAD [] +synonym: "tectonic complex" NARROW [] +synonym: "tectonic-like complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0035869 ! ciliary transition zone +created_by: bf +creation_date: 2011-11-22T11:21:28Z + +[Term] +id: GO:0036039 +name: curcumin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the polyphenol, curcumin." [PMID:21467222] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process" EXACT [GOC:obol] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism" EXACT [GOC:obol] +synonym: "curcumin metabolism" EXACT [GOC:obol] +synonym: "diferuloylmethane metabolic process" EXACT [GOC:obol] +synonym: "diferuloylmethane metabolism" EXACT [GOC:obol] +synonym: "turmeric yellow metabolic process" EXACT [GOC:obol] +synonym: "turmeric yellow metabolism" EXACT [GOC:obol] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +created_by: bf +creation_date: 2011-11-22T01:58:57Z + +[Term] +id: GO:0036040 +name: curcumin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin." [PMID:21467222] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown" EXACT [GOC:obol] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process" EXACT [GOC:obol] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism" EXACT [GOC:obol] +synonym: "(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation" EXACT [GOC:obol] +synonym: "curcumin breakdown" EXACT [GOC:obol] +synonym: "curcumin catabolism" EXACT [GOC:obol] +synonym: "curcumin degradation" EXACT [GOC:obol] +synonym: "diferuloylmethane breakdown" EXACT [GOC:obol] +synonym: "diferuloylmethane catabolic process" EXACT [GOC:obol] +synonym: "diferuloylmethane catabolism" EXACT [GOC:obol] +synonym: "diferuloylmethane degradation" EXACT [GOC:obol] +synonym: "turmeric yellow breakdown" EXACT [GOC:obol] +synonym: "turmeric yellow catabolic process" EXACT [GOC:obol] +synonym: "turmeric yellow catabolism" EXACT [GOC:obol] +synonym: "turmeric yellow degradation" EXACT [GOC:obol] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0036039 ! curcumin metabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: bf +creation_date: 2011-11-22T02:01:05Z + +[Term] +id: GO:0036041 +name: long-chain fatty acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:pm, PMID:12641450] +synonym: "long chain fatty acid binding" EXACT [PMID:12641450] +is_a: GO:0005504 ! fatty acid binding +created_by: bf +creation_date: 2011-11-24T02:54:39Z + +[Term] +id: GO:0036042 +name: long-chain fatty acyl-CoA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a long-chain fatty acyl-CoA. A long-chain fatty acyl-CoA is any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more." [GOC:pm] +is_a: GO:0000062 ! fatty-acyl-CoA binding +created_by: bf +creation_date: 2011-11-24T04:31:09Z + +[Term] +id: GO:0036043 +name: obsolete microspike +namespace: cellular_component +def: "OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell." [PMID:11429692, PMID:12153987, PMID:19095735] +comment: This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044393. +synonym: "microspike" EXACT [] +is_obsolete: true +replaced_by: GO:0044393 +created_by: bf +creation_date: 2011-12-06T01:31:16Z + +[Term] +id: GO:0036044 +name: obsolete protein malonylation +namespace: biological_process +def: "OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group." [GOC:sp] +comment: This term was made obsolete because it accidentally shared the same ID as negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway by negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity. New id is GO:0044394. +synonym: "protein malonylation" EXACT [] +is_obsolete: true +replaced_by: GO:0044394 + +[Term] +id: GO:0036045 +name: obsolete peptidyl-lysine malonylation +namespace: biological_process +def: "OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine." [GOC:jsg, GOC:sp, PMID:21908771, PMID:22076378, RESID:AA0568] +comment: This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044392. +synonym: "lysine malonylation" EXACT [PMID:21908771] +synonym: "peptidyl-lysine malonylation" EXACT [] +xref: RESID:AA0568 +is_obsolete: true +replaced_by: GO:0044392 +created_by: bf +creation_date: 2011-12-12T09:31:42Z + +[Term] +id: GO:0036046 +name: protein demalonylation +namespace: biological_process +def: "The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide." [GOC:sp, PMID:22076378] +is_a: GO:0035601 ! protein deacylation +created_by: bf +creation_date: 2011-12-12T09:38:26Z + +[Term] +id: GO:0036047 +name: peptidyl-lysine demalonylation +namespace: biological_process +def: "The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein." [GOC:sp, PMID:22076378] +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0036046 ! protein demalonylation +created_by: bf +creation_date: 2011-12-12T09:39:17Z + +[Term] +id: GO:0036048 +name: protein desuccinylation +namespace: biological_process +def: "The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein." [GOC:sp, PMID:22076378] +is_a: GO:0035601 ! protein deacylation +created_by: bf +creation_date: 2011-12-12T09:42:35Z + +[Term] +id: GO:0036049 +name: peptidyl-lysine desuccinylation +namespace: biological_process +def: "The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein." [GOC:sp, PMID:22076378] +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0036048 ! protein desuccinylation +created_by: bf +creation_date: 2011-12-12T09:44:54Z + +[Term] +id: GO:0036050 +name: peptidyl-lysine succinylation +namespace: biological_process +def: "The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine." [GOC:jsg, GOC:sp, PMID:21151122, RESID:AA0545] +xref: RESID:AA0545 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018335 ! protein succinylation +created_by: bf +creation_date: 2011-12-12T09:51:27Z + +[Term] +id: GO:0036051 +name: protein localization to trailing edge +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement." [GOC:pf, GOC:pg] +synonym: "protein localisation to trailing edge" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +created_by: bf +creation_date: 2011-12-12T10:44:04Z + +[Term] +id: GO:0036052 +name: protein localization to uropod +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell." [GOC:add, GOC:pf, ISBN:0781735149, PMID:12714569, PMID:12787750] +synonym: "protein localisation to uropod" EXACT [GOC:mah] +is_a: GO:0036051 ! protein localization to trailing edge +created_by: bf +creation_date: 2011-12-12T10:45:26Z + +[Term] +id: GO:0036053 +name: glomerular endothelium fenestra +namespace: cellular_component +def: "A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes." [GOC:cjm, MP:0011454, PMID:19129259] +synonym: "GEnC fenestration" EXACT [PMID:19129259] +synonym: "glomerular endothelial cell fenestration" EXACT [PMID:19129259] +is_a: GO:0046930 ! pore complex +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: bf +creation_date: 2011-12-12T10:53:24Z + +[Term] +id: GO:0036054 +name: protein-malonyllysine demalonylase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide." [GOC:sp, PMID:21908771, PMID:22076378] +synonym: "peptidyl-malonyllysine demalonylase activity" EXACT [] +synonym: "protein lysine demalonylation activity" EXACT [PMID:21908771] +synonym: "protein malonyl lysine demalonylation activity" EXACT [GOC:bf] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +relationship: part_of GO:0036047 ! peptidyl-lysine demalonylation +created_by: bf +creation_date: 2011-12-12T01:29:21Z + +[Term] +id: GO:0036055 +name: protein-succinyllysine desuccinylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [GOC:sp, PMID:22076378] +comment: This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide. +synonym: "peptidyl-succinyllysine desuccinylase activity" EXACT [] +synonym: "succinyl lysine desuccinylase activity" BROAD [GOC:bf] +synonym: "succinyllysine desuccinylase activity" BROAD [] +xref: RHEA:47668 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +relationship: part_of GO:0036049 ! peptidyl-lysine desuccinylation +created_by: bf +creation_date: 2011-12-12T01:33:51Z + +[Term] +id: GO:0036056 +name: filtration diaphragm +namespace: cellular_component +def: "A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph." [GOC:mtg_kidney_jan10, GOC:sart, PMID:18971929] +is_a: GO:0005911 ! cell-cell junction +created_by: bf +creation_date: 2011-12-12T04:36:05Z + +[Term] +id: GO:0036057 +name: slit diaphragm +namespace: cellular_component +def: "A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration." [GOC:mtg_kidney_jan10, GOC:rph, PMID:12386277, PMID:15994232, PMID:18971929, PMID:19478094] +is_a: GO:0036056 ! filtration diaphragm +created_by: bf +creation_date: 2011-12-12T04:36:42Z + +[Term] +id: GO:0036058 +name: filtration diaphragm assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph." [GOC:mtg_kidney_jan10, PMID:18971929] +is_a: GO:0007043 ! cell-cell junction assembly +created_by: bf +creation_date: 2011-12-12T04:38:40Z + +[Term] +id: GO:0036059 +name: nephrocyte diaphragm assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney." [GOC:mtg_kidney_jan10, GOC:sart, PMID:18971929] +is_a: GO:0034333 ! adherens junction assembly +is_a: GO:0036058 ! filtration diaphragm assembly +created_by: bf +creation_date: 2011-12-12T04:38:40Z + +[Term] +id: GO:0036060 +name: slit diaphragm assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration." [GOC:mtg_kidney_jan10, GOC:rph, PMID:20633639] +is_a: GO:0036058 ! filtration diaphragm assembly +created_by: bf +creation_date: 2011-12-12T04:38:40Z + +[Term] +id: GO:0036061 +name: muscle cell chemotaxis toward tendon cell +namespace: biological_process +def: "The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells." [GOC:sart, PMID:19793885] +synonym: "muscle cell attraction" RELATED [GOC:bf] +synonym: "muscle cell chemotaxis towards tendon cell" EXACT [GOC:bf, GOC:sart] +is_a: GO:0014812 ! muscle cell migration +is_a: GO:0060326 ! cell chemotaxis +created_by: bf +creation_date: 2011-12-14T11:13:40Z + +[Term] +id: GO:0036062 +name: presynaptic periactive zone +namespace: cellular_component +def: "A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development." [GOC:sart, PMID:10976048, PMID:18439406] +synonym: "periactive zone" EXACT [PMID:10976048, PMID:18439406] +synonym: "pre-synaptic periactive zone" EXACT [] +is_a: GO:0097060 ! synaptic membrane +relationship: part_of GO:0042734 ! presynaptic membrane +created_by: bf +creation_date: 2011-12-14T02:25:29Z + +[Term] +id: GO:0036063 +name: acroblast +namespace: cellular_component +def: "A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle." [GOC:sart, PMID:19934220] +comment: See also the fly_anatomy.ontology term 'acroblast ; FBbt:00004947'. +synonym: "spermatid acroblast" EXACT [GOC:bf] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005794 ! Golgi apparatus +created_by: bf +creation_date: 2011-12-14T02:29:05Z + +[Term] +id: GO:0036064 +name: ciliary basal body +namespace: cellular_component +alt_id: GO:0005932 +def: "A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport." [GOC:cilia, GOC:clt, PMID:21750193] +comment: In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. +synonym: "basal body" BROAD [] +synonym: "cilial basal body" EXACT [] +synonym: "cilium basal body" EXACT [GOC:bf] +synonym: "microtubule basal body" EXACT [] +xref: NIF_Subcellular:sao11978067 +is_a: GO:0005815 ! microtubule organizing center +intersection_of: GO:0005815 ! microtubule organizing center +intersection_of: part_of GO:0005929 ! cilium +relationship: part_of GO:0005929 ! cilium +created_by: bf +creation_date: 2011-12-15T10:40:20Z + +[Term] +id: GO:0036065 +name: fucosylation +namespace: biological_process +def: "The covalent attachment of a fucosyl group to an acceptor molecule." [GOC:sart, PMID:19948734] +is_a: GO:0070085 ! glycosylation +created_by: bf +creation_date: 2011-12-15T11:16:19Z + +[Term] +id: GO:0036066 +name: protein O-linked fucosylation +namespace: biological_process +def: "The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage." [GOC:sart, PMID:19948734] +is_a: GO:0006493 ! protein O-linked glycosylation +is_a: GO:0036065 ! fucosylation +created_by: bf +creation_date: 2011-12-15T11:17:20Z + +[Term] +id: GO:0036067 +name: light-dependent chlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light." [GOC:yaf, PMID:12242396] +synonym: "light dependent chlorophyll biosynthetic process" EXACT [GOC:yaf] +synonym: "light-dependent chlorophyll anabolism" EXACT [GOC:bf] +synonym: "light-dependent chlorophyll biosynthesis" EXACT [GOC:bf] +synonym: "light-dependent chlorophyll formation" EXACT [GOC:bf] +synonym: "light-dependent chlorophyll synthesis" EXACT [GOC:bf] +is_a: GO:0015995 ! chlorophyll biosynthetic process +created_by: bf +creation_date: 2011-12-15T04:42:47Z + +[Term] +id: GO:0036068 +name: light-independent chlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light." [GOC:yaf, PMID:12242396, UniPathway:UPA00670] +synonym: "light independent chlorophyll biosynthetic process" EXACT [GOC:yaf] +synonym: "light-independent chlorophyll anabolism" EXACT [GOC:bf] +synonym: "light-independent chlorophyll biosynthesis" EXACT [GOC:bf] +synonym: "light-independent chlorophyll formation" EXACT [GOC:bf] +synonym: "light-independent chlorophyll synthesis" EXACT [GOC:bf] +is_a: GO:0015995 ! chlorophyll biosynthetic process +created_by: bf +creation_date: 2011-12-15T04:44:18Z + +[Term] +id: GO:0036069 +name: light-dependent bacteriochlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants." [GOC:yaf, PMID:12242396] +synonym: "light dependent bacteriochlorophyll biosynthetic process" EXACT [GOC:bf] +synonym: "light-dependent bacteriochlorophyll anabolism" EXACT [GOC:bf] +synonym: "light-dependent bacteriochlorophyll biosynthesis" EXACT [GOC:bf] +synonym: "light-dependent bacteriochlorophyll formation" EXACT [GOC:bf] +synonym: "light-dependent bacteriochlorophyll synthesis" EXACT [GOC:bf] +is_a: GO:0030494 ! bacteriochlorophyll biosynthetic process +is_a: GO:0036067 ! light-dependent chlorophyll biosynthetic process +created_by: bf +creation_date: 2011-12-15T04:45:16Z + +[Term] +id: GO:0036070 +name: light-independent bacteriochlorophyll biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants." [GOC:yaf, PMID:12242396, UniPathway:UPA00671] +synonym: "light independent bacteriochlorophyll biosynthetic process" EXACT [GOC:bf] +synonym: "light-independent bacteriochlorophyll anabolism" EXACT [GOC:bf] +synonym: "light-independent bacteriochlorophyll biosynthesis" EXACT [GOC:bf] +synonym: "light-independent bacteriochlorophyll formation" EXACT [GOC:bf] +synonym: "light-independent bacteriochlorophyll synthesis" EXACT [GOC:bf] +is_a: GO:0030494 ! bacteriochlorophyll biosynthetic process +is_a: GO:0036068 ! light-independent chlorophyll biosynthetic process +created_by: bf +creation_date: 2011-12-15T04:46:25Z + +[Term] +id: GO:0036071 +name: N-glycan fucosylation +namespace: biological_process +def: "The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains." [GOC:sart, PMID:19948734] +synonym: "glycoprotein fucosylation" RELATED [GOC:bf] +is_a: GO:0036065 ! fucosylation +created_by: bf +creation_date: 2011-12-15T04:54:24Z + +[Term] +id: GO:0036072 +name: direct ossification +namespace: biological_process +def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034] +is_a: GO:0001503 ! ossification +created_by: bf +creation_date: 2011-12-19T01:47:22Z + +[Term] +id: GO:0036073 +name: perichondral ossification +namespace: biological_process +def: "Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage." [GO_REF:0000034] +is_a: GO:0001957 ! intramembranous ossification +created_by: bf +creation_date: 2011-12-19T01:49:38Z + +[Term] +id: GO:0036074 +name: metaplastic ossification +namespace: biological_process +def: "Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division." [GO_REF:0000034] +comment: Some intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. +synonym: "metaplasia" RELATED [GO_REF:0000034] +is_a: GO:0036072 ! direct ossification +created_by: bf +creation_date: 2011-12-19T01:50:35Z + +[Term] +id: GO:0036075 +name: replacement ossification +namespace: biological_process +def: "Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation." [GO_REF:0000034] +synonym: "indirect ossification" EXACT [GO_REF:0000034] +is_a: GO:0001503 ! ossification +created_by: bf +creation_date: 2011-12-19T01:53:16Z + +[Term] +id: GO:0036076 +name: ligamentous ossification +namespace: biological_process +def: "Ossification wherein bone tissue forms within ligamentous tissue." [GO_REF:0000034] +comment: Ligamentous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance. +is_a: GO:0001503 ! ossification +created_by: bf +creation_date: 2011-12-19T01:57:08Z + +[Term] +id: GO:0036077 +name: intratendonous ossification +namespace: biological_process +def: "Ossification wherein bone tissue forms within tendonous tissue." [GO_REF:0000034] +comment: Tendonous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance. +is_a: GO:0001503 ! ossification +created_by: bf +creation_date: 2011-12-19T01:57:48Z + +[Term] +id: GO:0036078 +name: minus-end specific microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from the minus end of a microtubule." [GOC:sart, PMID:17452528] +is_a: GO:0007019 ! microtubule depolymerization +created_by: bf +creation_date: 2011-12-19T03:20:25Z + +[Term] +id: GO:0036080 +name: purine nucleotide-sugar transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:sart, PMID:19948734] +is_a: GO:0005338 ! nucleotide-sugar transmembrane transporter activity +relationship: part_of GO:0090480 ! purine nucleotide-sugar transmembrane transport +created_by: bf +creation_date: 2011-12-19T03:29:06Z + +[Term] +id: GO:0036081 +name: extracellular ammonia-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts." [GOC:sart, PMID:19135896] +synonym: "ionotropic ammonia receptor activity" RELATED [PMID:19135896] +is_a: GO:0005230 ! extracellular ligand-gated ion channel activity +created_by: bf +creation_date: 2011-12-20T04:47:48Z + +[Term] +id: GO:0036082 +name: extracellular phenylacetaldehyde-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts." [GOC:sart, PMID:19135896] +synonym: "ionotropic phenylacetaldehyde receptor activity" RELATED [PMID:19135896] +is_a: GO:0005230 ! extracellular ligand-gated ion channel activity +created_by: bf +creation_date: 2011-12-20T04:49:31Z + +[Term] +id: GO:0036083 +name: obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:9927444] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: bf +creation_date: 2011-12-20T04:52:36Z + +[Term] +id: GO:0036084 +name: GDP-fucose import into endoplasmic reticulum lumen +namespace: biological_process +def: "The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate." [GOC:sart, PMID:3458237] +synonym: "GDP-fucose import into endoplasmic reticulum" EXACT [GOC:bf] +synonym: "GDP-fucose transport across endoplasmic reticulum membrane" EXACT [GOC:bf] +synonym: "GDP-fucose transport into endoplasmic reticulum lumen" EXACT [GOC:sart] +is_a: GO:0015783 ! GDP-fucose transmembrane transport +is_a: GO:0046967 ! cytosol to endoplasmic reticulum transport +created_by: bf +creation_date: 2011-12-21T01:45:11Z + +[Term] +id: GO:0036085 +name: GDP-fucose import into Golgi lumen +namespace: biological_process +def: "The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate." [GOC:sart, PMID:3458237] +synonym: "GDP-fucose import into Golgi" EXACT [GOC:bf] +synonym: "GDP-fucose transport across Golgi membrane" EXACT [GOC:bf] +synonym: "GDP-fucose transport into Golgi lumen" EXACT [GOC:sart] +is_a: GO:0015783 ! GDP-fucose transmembrane transport +created_by: bf +creation_date: 2011-12-21T01:52:10Z + +[Term] +id: GO:0036086 +name: positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions." [GOC:cjk] +synonym: "positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency" EXACT [GOC:bf] +is_a: GO:0033217 ! regulation of transcription from RNA polymerase II promoter in response to iron ion starvation +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +created_by: bf +creation_date: 2012-01-05T01:45:26Z + +[Term] +id: GO:0036087 +name: glutathione synthase complex +namespace: cellular_component +def: "A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer." [GOC:al, PMID:12734194, PMID:14990577, PMID:1958212] +synonym: "glutathione synthetase complex" EXACT [PMID:12734194, PMID:14990577, PMID:1958212] +is_a: GO:1902494 ! catalytic complex +created_by: bf +creation_date: 2012-01-05T04:29:20Z + +[Term] +id: GO:0036088 +name: D-serine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid." [GOC:imk] +synonym: "D-serine breakdown" EXACT [GOC:bf] +synonym: "D-serine catabolism" EXACT [GOC:bf] +synonym: "D-serine degradation" EXACT [GOC:bf] +is_a: GO:0009071 ! serine family amino acid catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0070178 ! D-serine metabolic process +created_by: bf +creation_date: 2012-01-06T10:58:51Z + +[Term] +id: GO:0036089 +name: cleavage furrow formation +namespace: biological_process +def: "Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell." [GOC:ans, PMID:15811947, PMID:20687468, PMID:2192590] +comment: Consider also annotating to 'establishment of contractile ring localization involved in cell cycle cytokinesis ; GO:0032188'. +synonym: "cleavage furrow positioning" NARROW [PMID:14757750] +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0099024 ! plasma membrane invagination +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: bf +creation_date: 2012-01-10T02:41:03Z + +[Term] +id: GO:0036090 +name: cleavage furrow ingression +namespace: biological_process +def: "Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed." [PMID:15811947, PMID:20687468] +comment: Consider also annotating to 'contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916'. +synonym: "cleavage furrow contraction" EXACT [PMID:3413069] +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0099024 ! plasma membrane invagination +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: bf +creation_date: 2012-01-10T02:46:05Z + +[Term] +id: GO:0036091 +name: positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:rn, PMID:14978214, PMID:18439143] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0043619 ! regulation of transcription from RNA polymerase II promoter in response to oxidative stress +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +created_by: bf +creation_date: 2012-01-10T02:54:43Z + +[Term] +id: GO:0036092 +name: phosphatidylinositol-3-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position." [GOC:al, GOC:vw] +synonym: "phosphatidylinositol-3-phosphate anabolism" EXACT [GOC:bf] +synonym: "phosphatidylinositol-3-phosphate biosynthesis" EXACT [GOC:bf] +synonym: "phosphatidylinositol-3-phosphate formation" EXACT [GOC:bf] +synonym: "phosphatidylinositol-3-phosphate synthesis" EXACT [GOC:bf] +synonym: "PI(3)P biosynthesis" EXACT [] +synonym: "PtdIns3P biosynthesis" EXACT [] +is_a: GO:0006661 ! phosphatidylinositol biosynthetic process +created_by: bf +creation_date: 2012-01-13T02:13:57Z + +[Term] +id: GO:0036093 +name: germ cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv] +is_a: GO:0008283 ! cell population proliferation +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007276 ! gamete generation +created_by: bf +creation_date: 2012-01-17T04:06:27Z + +[Term] +id: GO:0036094 +name: small molecule binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:pm] +comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. +subset: goslim_agr +subset: goslim_flybase_ribbon +is_a: GO:0005488 ! binding +created_by: bf +creation_date: 2012-01-17T04:20:34Z + +[Term] +id: GO:0036095 +name: obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:jh, PMID:14668363] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "transcriptional activation of genes involved in invasive growth" RELATED [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-24T10:53:28Z + +[Term] +id: GO:0036096 +name: obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing +namespace: molecular_function +def: "OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA." [GOC:sart, PMID:22055292] +comment: This term was made obsolete because it is not real a process, and was created accidentally. +synonym: "3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing" EXACT [] +synonym: "exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA" RELATED [GOC:sart] +is_obsolete: true +created_by: bf +creation_date: 2012-01-24T02:29:03Z + +[Term] +id: GO:0036097 +name: obsolete pre-miRNA 3'-end processing +namespace: biological_process +def: "OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA." [GOC:sart, PMID:22055292] +comment: This term was made obsolete because it is not real a process, and was created accidentally. +synonym: "microRNA 3'-end processing" BROAD [PMID:22055292] +synonym: "miRNA 3'-end processing" BROAD [PMID:22055292] +synonym: "pre-miRNA 3'-end processing" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2012-01-24T02:31:37Z + +[Term] +id: GO:0036098 +name: male germ-line stem cell population maintenance +namespace: biological_process +def: "The process by which an organism or tissue maintains a population of male germ-line stem cells." [GOC:sart, PMID:21752937] +is_a: GO:0030718 ! germ-line stem cell population maintenance +created_by: bf +creation_date: 2012-01-26T01:58:10Z + +[Term] +id: GO:0036099 +name: female germ-line stem cell population maintenance +namespace: biological_process +def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart] +is_a: GO:0030718 ! germ-line stem cell population maintenance +created_by: bf +creation_date: 2012-01-26T01:58:10Z + +[Term] +id: GO:0036100 +name: leukotriene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid." [GOC:yaf] +synonym: "leukotriene breakdown" EXACT [GOC:bf] +synonym: "leukotriene catabolism" EXACT [GOC:bf] +synonym: "leukotriene degradation" EXACT [GOC:bf] +is_a: GO:0006691 ! leukotriene metabolic process +is_a: GO:1901523 ! icosanoid catabolic process +created_by: bf +creation_date: 2012-01-27T01:26:24Z + +[Term] +id: GO:0036101 +name: leukotriene B4 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents." [GOC:yaf, PMID:9799565, UniPathway:UPA00883] +synonym: "leukotriene B4 breakdown" EXACT [GOC:bf] +synonym: "leukotriene B4 catabolism" EXACT [GOC:bf] +synonym: "leukotriene B4 degradation" EXACT [GOC:bf] +synonym: "LTB4 catabolism" EXACT [] +is_a: GO:0036100 ! leukotriene catabolic process +is_a: GO:0036102 ! leukotriene B4 metabolic process +is_a: GO:0042758 ! long-chain fatty acid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +created_by: bf +creation_date: 2012-01-27T01:26:24Z + +[Term] +id: GO:0036102 +name: leukotriene B4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents." [GOC:bf] +synonym: "LTB4 metabolism" EXACT [] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0006691 ! leukotriene metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: bf +creation_date: 2012-01-27T01:39:43Z + +[Term] +id: GO:0036103 +name: Kdo2-lipid A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component." [GOC:bf] +synonym: "Kdo2-lipid A metabolism" EXACT [GOC:bf] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:1901269 ! lipooligosaccharide metabolic process +created_by: bf +creation_date: 2012-01-27T01:49:16Z + +[Term] +id: GO:0036104 +name: Kdo2-lipid A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component." [GOC:yaf, UniPathway:UPA00360] +synonym: "di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis" EXACT [UniPathway:UPA00360] +synonym: "KDO(2)-lipid A biosynthesis" EXACT [UniPathway:UPA00360] +synonym: "Kdo2-lipid A anabolism" EXACT [GOC:bf] +synonym: "Kdo2-lipid A biosynthesis" EXACT [GOC:bf] +synonym: "Kdo2-lipid A formation" EXACT [GOC:bf] +synonym: "Kdo2-lipid A synthesis" EXACT [GOC:bf] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0036103 ! Kdo2-lipid A metabolic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:1901271 ! lipooligosaccharide biosynthetic process +created_by: bf +creation_date: 2012-01-27T01:49:23Z + +[Term] +id: GO:0036105 +name: peroxisome membrane class-1 targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner." [GOC:pm, PMID:14709540, PMID:17020786] +comment: Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence. +synonym: "class 1 mPTS binding" EXACT [PMID:14709540] +synonym: "PEX19-dependent mPTS binding" RELATED [PMID:14709540] +is_a: GO:0033328 ! peroxisome membrane targeting sequence binding +created_by: bf +creation_date: 2012-01-27T02:02:22Z + +[Term] +id: GO:0036106 +name: peroxisome membrane class-2 targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner." [GOC:pm, PMID:14709540, PMID:17020786] +comment: Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence. +synonym: "class 2 mPTS binding" EXACT [PMID:14709540] +synonym: "PEX19-independent mPTS binding" RELATED [PMID:14709540] +is_a: GO:0033328 ! peroxisome membrane targeting sequence binding +created_by: bf +creation_date: 2012-01-27T02:02:22Z + +[Term] +id: GO:0036107 +name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)." [PMID:15695810] +synonym: "4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process" EXACT [] +synonym: "undecaprenyl phosphate alpha-L-Ara4N metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process +created_by: bf +creation_date: 2012-02-06T02:55:42Z + +[Term] +id: GO:0036108 +name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)." [GOC:yaf, PMID:15695810, UniPathway:UPA00036] +synonym: "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism" EXACT [GOC:bf] +synonym: "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis" EXACT [GOC:bf] +synonym: "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation" EXACT [GOC:bf] +synonym: "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis" EXACT [GOC:bf] +synonym: "undecaprenyl phosphate alpha-L-Ara4N biosynthesis" EXACT [] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0036107 ! 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process +created_by: bf +creation_date: 2012-02-06T02:58:03Z + +[Term] +id: GO:0036109 +name: alpha-linolenic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2." [PMID:15538555] +synonym: "ALA metabolism" EXACT [CHEBI:27432] +synonym: "alpha-linolenic acid metabolism" EXACT [GOC:bf] +xref: Wikipedia:Linoleic_acid +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process +created_by: bf +creation_date: 2012-02-15T10:16:42Z + +[Term] +id: GO:0036110 +name: cellular response to inositol starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol." [GOC:al, PMID:19606215] +is_a: GO:0009267 ! cellular response to starvation +created_by: bf +creation_date: 2012-02-15T10:46:07Z + +[Term] +id: GO:0036111 +name: very long-chain fatty-acyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [GOC:pm] +synonym: "very long-chain fatty acyl CoA metabolic process" EXACT [GOC:bf] +synonym: "very long-chain fatty acyl-CoA metabolism" EXACT [GOC:bf] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: bf +creation_date: 2012-02-15T11:09:22Z + +[Term] +id: GO:0036112 +name: medium-chain fatty-acyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12." [GOC:pm] +synonym: "medium-chain fatty acyl CoA metabolic process" EXACT [GOC:bf] +synonym: "medium-chain fatty acyl-CoA metabolism" EXACT [GOC:bf] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: bf +creation_date: 2012-02-15T11:12:19Z + +[Term] +id: GO:0036113 +name: very long-chain fatty-acyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22." [GOC:pm] +synonym: "very long-chain fatty-acyl-CoA breakdown" EXACT [GOC:bf] +synonym: "very long-chain fatty-acyl-CoA catabolism" EXACT [GOC:bf] +synonym: "very long-chain fatty-acyl-CoA degradation" EXACT [GOC:bf] +is_a: GO:0036111 ! very long-chain fatty-acyl-CoA metabolic process +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +created_by: bf +creation_date: 2012-02-15T11:16:11Z + +[Term] +id: GO:0036114 +name: medium-chain fatty-acyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12." [GOC:pm] +synonym: "medium-chain fatty-acyl-CoA breakdown" EXACT [GOC:bf] +synonym: "medium-chain fatty-acyl-CoA catabolism" EXACT [GOC:bf] +synonym: "medium-chain fatty-acyl-CoA degradation" EXACT [GOC:bf] +is_a: GO:0036112 ! medium-chain fatty-acyl-CoA metabolic process +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +created_by: bf +creation_date: 2012-02-15T11:23:16Z + +[Term] +id: GO:0036115 +name: fatty-acyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group." [PMID:10578051] +synonym: "fatty-acyl-CoA breakdown" EXACT [GOC:bf] +synonym: "fatty-acyl-CoA catabolism" EXACT [GOC:bf] +synonym: "fatty-acyl-CoA degradation" EXACT [GOC:bf] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901569 ! fatty acid derivative catabolic process +created_by: bf +creation_date: 2012-02-15T11:26:25Z + +[Term] +id: GO:0036116 +name: long-chain fatty-acyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:pm] +synonym: "long-chain fatty-acyl-CoA breakdown" EXACT [GOC:bf] +synonym: "long-chain fatty-acyl-CoA catabolism" EXACT [GOC:bf] +synonym: "long-chain fatty-acyl-CoA degradation" EXACT [GOC:bf] +is_a: GO:0035336 ! long-chain fatty-acyl-CoA metabolic process +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +created_by: bf +creation_date: 2012-02-15T11:30:24Z + +[Term] +id: GO:0036117 +name: hyaluranon cable +namespace: cellular_component +def: "A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan." [GOC:yaf, PMID:16900089] +synonym: "HA cable" EXACT [PMID:16900089] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region +created_by: bf +creation_date: 2012-02-16T10:53:37Z + +[Term] +id: GO:0036118 +name: hyaluranon cable assembly +namespace: biological_process +def: "A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan." [GOC:yaf, PMID:16900089] +synonym: "HA cable assembly" EXACT [PMID:16900089] +is_a: GO:0022607 ! cellular component assembly +created_by: bf +creation_date: 2012-02-16T11:06:58Z + +[Term] +id: GO:0036119 +name: response to platelet-derived growth factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus." [GOC:yaf] +synonym: "response to PDGF stimulus" EXACT [GOC:bf] +synonym: "response to platelet-derived growth factor stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: bf +creation_date: 2012-02-20T02:48:00Z + +[Term] +id: GO:0036120 +name: cellular response to platelet-derived growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus." [GOC:yaf] +synonym: "cellular response to PDGF stimulus" EXACT [GOC:bf] +is_a: GO:0036119 ! response to platelet-derived growth factor +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +created_by: bf +creation_date: 2012-02-20T02:49:02Z + +[Term] +id: GO:0036121 +name: double-stranded DNA helicase activity +namespace: molecular_function +alt_id: GO:0033676 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix." [GOC:kmv] +synonym: "double-stranded DNA-dependent ATP-dependent DNA helicase activity" EXACT [] +synonym: "double-stranded DNA-dependent ATPase activity" EXACT [] +synonym: "dsDNA-dependent ATP-dependent DNA helicase activity" EXACT [GOC:kmv] +synonym: "dsDNA-dependent ATPase activity" EXACT [] +is_a: GO:0003678 ! DNA helicase activity +created_by: bf +creation_date: 2012-02-20T02:53:51Z + +[Term] +id: GO:0036122 +name: BMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family." [GOC:BHF, PMID:9660951, PR:000000034] +synonym: "bone morphogenetic protein binding" EXACT [GOC:bf] +is_a: GO:0019955 ! cytokine binding +created_by: bf +creation_date: 2012-02-20T02:59:34Z + +[Term] +id: GO:0036123 +name: histone H3-K9 dimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone." [GOC:vw] +synonym: "histone H3 K9 dimethylation" EXACT [] +synonym: "histone lysine H3 K9 dimethylation" EXACT [] +is_a: GO:0018027 ! peptidyl-lysine dimethylation +is_a: GO:0051567 ! histone H3-K9 methylation +created_by: bf +creation_date: 2012-02-20T03:06:15Z + +[Term] +id: GO:0036124 +name: histone H3-K9 trimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone." [GOC:vw] +is_a: GO:0018023 ! peptidyl-lysine trimethylation +is_a: GO:0051567 ! histone H3-K9 methylation +created_by: bf +creation_date: 2012-02-20T03:08:06Z + +[Term] +id: GO:0036125 +name: fatty acid beta-oxidation multienzyme complex +namespace: cellular_component +def: "A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT)." [GOC:imk, PMID:12115060, PMID:16472743] +comment: For fatty acid beta-oxidation multienzyme complexes located in the mitochondrial matrix, consider instead the term 'mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507'. +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2012-02-28T02:10:39Z + +[Term] +id: GO:0036126 +name: sperm flagellum +namespace: cellular_component +def: "A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid." [GOC:cilia, GOC:sart, PMID:8441407] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is always 'flagellum', hence the primary term name, but the cilium parentage is deliberate. +synonym: "sperm cilium" EXACT [] +synonym: "sperm tail" EXACT [GOC:sart] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: bf +creation_date: 2012-02-28T02:39:00Z + +[Term] +id: GO:0036127 +name: 3-sulfino-L-alanine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 3-sulfino-L-alanine (cysteine sulfinate)." [GOC:al, PMID:8346915] +synonym: "cysteine sulfinate binding" EXACT [GOC:al] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0072341 ! modified amino acid binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bf +creation_date: 2012-02-28T03:15:40Z + +[Term] +id: GO:0036128 +name: CatSper complex +namespace: cellular_component +def: "A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits." [GOC:sp, PMID:17478420, PMID:21224844, PMID:22354039] +synonym: "CATSPER channel" EXACT [PMID:21224844] +synonym: "CatSper channel complex" EXACT [PMID:17478420] +is_a: GO:0005891 ! voltage-gated calcium channel complex +created_by: bf +creation_date: 2012-03-02T10:26:48Z + +[Term] +id: GO:0036129 +name: obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus." [GOC:al] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: bf +creation_date: 2012-03-02T10:36:39Z + +[Term] +id: GO:0036130 +name: prostaglandin H2 endoperoxidase reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate)." [GOC:mw, KEGG_REACTION:R02264, PMID:10622721, PMID:14979715, PMID:16475787] +synonym: "PGH2 9,11-endoperoxidase" EXACT [PMID:12664595] +synonym: "PGH2 9-,11-endoperoxide reductase" EXACT [PMID:12432932] +xref: KEGG_REACTION:R02264 +xref: Reactome:R-HSA-2161549 "PGH2 is reduced to PGF2a by AKR1C3" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +relationship: part_of GO:0006693 ! prostaglandin metabolic process +created_by: bf +creation_date: 2012-03-05T09:25:03Z + +[Term] +id: GO:0036131 +name: prostaglandin D2 11-ketoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+." [EC:1.1.1.188, GOC:mw, KEGG_REACTION:R02799, PMID:1504718, PMID:3862115] +synonym: "PGD2 11-ketoreductase" EXACT [PMID:14996743] +synonym: "prostaglandin 11-keto reductase" EXACT [PMID:7248318] +xref: EC:1.1.1.188 +xref: KEGG_REACTION:R02799 +xref: Reactome:R-HSA-2161614 "PGD2 is reduced to 11-epi-PGF2a by AKRIC3" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +relationship: part_of GO:0006693 ! prostaglandin metabolic process +created_by: bf +creation_date: 2012-03-05T10:27:29Z + +[Term] +id: GO:0036132 +name: 13-prostaglandin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin." [EC:1.3.1.48, GOC:mw, KEGG_REACTION:R04556, KEGG_REACTION:R04557, PMID:17449869] +comment: Note that this is the reverse of the reaction described in '15-oxoprostaglandin 13-oxidase activity ; GO:0047522'. +synonym: "15-ketoprostaglandin delta13-reductase activity" EXACT [EC:1.3.1.48] +synonym: "15-oxo-delta13-prostaglandin reductase activity" EXACT [EC:1.3.1.48] +synonym: "15-oxoprostaglandin 13-reductase activity" EXACT [] +synonym: "delta13-15-ketoprostaglandin reductase activity" EXACT [EC:1.3.1.48] +synonym: "prostaglandin 13-reductase activity" EXACT [EC:1.3.1.48] +synonym: "prostaglandin delta13-reductase activity" EXACT [EC:1.3.1.48] +xref: EC:1.3.1.48 +xref: KEGG_REACTION:R04556 +xref: KEGG_REACTION:R04557 +xref: Reactome:R-HSA-2161692 "15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +relationship: part_of GO:0006693 ! prostaglandin metabolic process +created_by: bf +creation_date: 2012-03-05T10:42:22Z + +[Term] +id: GO:0036133 +name: 11-hydroxythromboxane B2 dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+." [GOC:mw, KEGG_REACTION:R05060, PMID:3461463, PMID:3823488, PMID:8200461] +comment: Note that the KEGG_REACTION:R05060 reaction does not stipulate the acceptor group, and is therefore slightly more general than the activity described by GO:0036133. +synonym: "NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity" EXACT [PMID:1632314] +xref: KEGG_REACTION:R05060 +xref: Reactome:R-HSA-2161732 "TXB2 is converted to 11dh-TXB2 by TXDH" +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2012-03-05T11:05:09Z + +[Term] +id: GO:0036134 +name: 12-hydroxyheptadecatrienoic acid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA)." [GOC:mw, PMID:11297515] +synonym: "prostaglandin H2 degradation activity" RELATED [GOC:mw] +xref: Reactome:R-HSA-2161613 "PGH2 is degraded to 12S-HHT and MDA by TBXAS1" +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2012-03-05T11:17:34Z + +[Term] +id: GO:0036135 +name: Schwann cell migration +namespace: biological_process +def: "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function." [CL:0002573, PMID:20335460] +is_a: GO:0008347 ! glial cell migration +created_by: bf +creation_date: 2012-03-06T10:44:39Z + +[Term] +id: GO:0036136 +name: kynurenine-oxaloacetate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate." [EC:2.6.1.-, GOC:pde, PMID:15606768, PMID:4149765] +synonym: "L-kynurenine-oxaloacetate transaminase activity" EXACT [GOC:bf] +is_a: GO:0036137 ! kynurenine aminotransferase activity +created_by: bf +creation_date: 2012-03-06T02:14:11Z + +[Term] +id: GO:0036137 +name: kynurenine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid." [EC:2.6.1.-, GOC:pde] +synonym: "kynurenine-oxo-acid transaminase activity" NARROW [GOC:bf] +synonym: "L-kynurenine transaminase activity" EXACT [GOC:bf] +is_a: GO:0008483 ! transaminase activity +relationship: part_of GO:0097052 ! L-kynurenine metabolic process +created_by: bf +creation_date: 2012-03-06T02:16:48Z + +[Term] +id: GO:0036138 +name: peptidyl-histidine hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine." [GOC:reh, PMID:21251231] +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0018202 ! peptidyl-histidine modification +created_by: bf +creation_date: 2012-03-07T09:25:25Z + +[Term] +id: GO:0036139 +name: peptidyl-histidine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2." [GOC:reh, PMID:21251231] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: bf +creation_date: 2012-03-07T09:26:54Z + +[Term] +id: GO:0036140 +name: peptidyl-asparagine 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2." [GOC:reh, PMID:12215170] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: bf +creation_date: 2012-03-07T09:27:44Z + +[Term] +id: GO:0036141 +name: L-phenylalanine-oxaloacetate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate." [GOC:pde, PMID:15606768] +synonym: "L-phenylalanine:oxaloacetate transaminase activity" EXACT [GOC:bf] +is_a: GO:0070546 ! L-phenylalanine aminotransferase activity +created_by: bf +creation_date: 2012-03-08T10:35:44Z + +[Term] +id: GO:0036143 +name: kringle domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors." [GOC:yaf, Wikipedia:Kringle_domain] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2012-03-09T09:49:43Z + +[Term] +id: GO:0036145 +name: dendritic cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316] +synonym: "DC homeostasis" RELATED [PMID:19176316] +is_a: GO:0001776 ! leukocyte homeostasis +created_by: bf +creation_date: 2012-03-12T11:05:36Z + +[Term] +id: GO:0036146 +name: cellular response to mycotoxin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi." [GOC:di, PMID:20548963] +is_a: GO:0010046 ! response to mycotoxin +is_a: GO:0097237 ! cellular response to toxic substance +created_by: bf +creation_date: 2012-03-12T11:08:22Z + +[Term] +id: GO:0036147 +name: rumination +namespace: biological_process +def: "A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again." [GOC:maf, Wikipedia:Rumination] +synonym: "digestive rumination" EXACT [Wikipedia:Rumination] +is_a: GO:0022600 ! digestive system process +created_by: bf +creation_date: 2012-03-13T04:35:19Z + +[Term] +id: GO:0036148 +name: phosphatidylglycerol acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains." [GOC:mw, PMID:15485873, PMID:18458083] +is_a: GO:0046471 ! phosphatidylglycerol metabolic process +created_by: bf +creation_date: 2012-03-14T01:14:23Z + +[Term] +id: GO:0036149 +name: phosphatidylinositol acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains." [GOC:mw, PMID:18094042, PMID:18772128] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +created_by: bf +creation_date: 2012-03-14T01:27:02Z + +[Term] +id: GO:0036150 +name: phosphatidylserine acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains." [GOC:mw, PMID:18287005, PMID:18458083] +synonym: "phosphatidyl-L-serine acyl-chain remodeling" NARROW [] +is_a: GO:0006658 ! phosphatidylserine metabolic process +created_by: bf +creation_date: 2012-03-14T01:35:44Z + +[Term] +id: GO:0036151 +name: phosphatidylcholine acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains." [GOC:mw, PMID:18195019, PMID:18458083] +is_a: GO:0046470 ! phosphatidylcholine metabolic process +created_by: bf +creation_date: 2012-03-14T01:54:13Z + +[Term] +id: GO:0036152 +name: phosphatidylethanolamine acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains." [GOC:mw, PMID:18287005, PMID:18458083] +is_a: GO:0046470 ! phosphatidylcholine metabolic process +created_by: bf +creation_date: 2012-03-14T02:09:00Z + +[Term] +id: GO:0036153 +name: triglyceride acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains." [GOC:mw, PMID:15364929] +synonym: "triacylglycerol acyl-chain remodeling" EXACT [GOC:mw, KEGG:C00422] +is_a: GO:0006641 ! triglyceride metabolic process +is_a: GO:0036155 ! acylglycerol acyl-chain remodeling +created_by: bf +creation_date: 2012-03-14T02:49:05Z + +[Term] +id: GO:0036154 +name: diacylglycerol acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains." [GOC:mw, PMID:15364929] +synonym: "diglyceride acyl-chain remodeling" EXACT [GOC:mw, KEGG:C00165] +is_a: GO:0036155 ! acylglycerol acyl-chain remodeling +is_a: GO:0046339 ! diacylglycerol metabolic process +created_by: bf +creation_date: 2012-03-14T02:53:14Z + +[Term] +id: GO:0036155 +name: acylglycerol acyl-chain remodeling +namespace: biological_process +def: "Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains." [GOC:mw, PMID:15364929] +synonym: "glyceride acyl-chain remodeling" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process +created_by: bf +creation_date: 2012-03-14T02:55:00Z + +[Term] +id: GO:0036156 +name: inner dynein arm +namespace: cellular_component +def: "Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility." [GOC:BHF, GOC:vk, PMID:19347929, PMID:2557057, PMID:7962092] +synonym: "inner dynein arm complex" EXACT [] +is_a: GO:0005858 ! axonemal dynein complex +created_by: bf +creation_date: 2012-03-21T01:24:54Z + +[Term] +id: GO:0036157 +name: outer dynein arm +namespace: cellular_component +def: "Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility." [GOC:BHF, GOC:vk, PMID:2557057, PMID:6218174] +synonym: "outer dynein arm complex" EXACT [] +is_a: GO:0005858 ! axonemal dynein complex +created_by: bf +creation_date: 2012-03-21T01:25:03Z + +[Term] +id: GO:0036158 +name: outer dynein arm assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes." [GOC:BHF, GOC:vk, PMID:19944400] +synonym: "ODA assembly" EXACT [PMID:19944400] +is_a: GO:0070286 ! axonemal dynein complex assembly +created_by: bf +creation_date: 2012-03-21T02:25:01Z + +[Term] +id: GO:0036159 +name: inner dynein arm assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes." [GOC:BHF, GOC:vk, PMID:19944400] +synonym: "IDA assembly" EXACT [PMID:19944400] +is_a: GO:0070286 ! axonemal dynein complex assembly +created_by: bf +creation_date: 2012-03-21T02:25:01Z + +[Term] +id: GO:0036160 +name: melanocyte-stimulating hormone secretion +namespace: biological_process +def: "The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation." [GOC:cjm, Wikipedia:Melanocyte-stimulating_hormone] +synonym: "MSH secretion" EXACT [GOC:cjm] +is_a: GO:0030072 ! peptide hormone secretion +created_by: bf +creation_date: 2012-03-26T01:16:55Z + +[Term] +id: GO:0036161 +name: calcitonin secretion +namespace: biological_process +def: "The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell." [GOC:cjm, PR:000027222] +is_a: GO:0015893 ! drug transport +is_a: GO:0030072 ! peptide hormone secretion +created_by: bf +creation_date: 2012-03-26T01:30:32Z + +[Term] +id: GO:0036162 +name: oxytocin secretion +namespace: biological_process +def: "The regulated release of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain, from a cell. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior." [GOC:cjm, Wikipedia:Oxytocin] +is_a: GO:0015893 ! drug transport +is_a: GO:0030072 ! peptide hormone secretion +created_by: bf +creation_date: 2012-03-26T01:43:46Z + +[Term] +id: GO:0036163 +name: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2." [GOC:mw, KEGG_REACTION:R06866, PMID:620805, PMID:7028108] +xref: KEGG_REACTION:R06866 +is_a: GO:0016831 ! carboxy-lyase activity +created_by: bf +creation_date: 2012-03-26T01:49:54Z + +[Term] +id: GO:0036164 +name: cell-abiotic substrate adhesion +namespace: biological_process +def: "The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules." [GOC:di] +synonym: "cell-abiotic surface adhesion" RELATED [GOC:di] +is_a: GO:0031589 ! cell-substrate adhesion +created_by: bf +creation_date: 2012-03-27T11:18:33Z + +[Term] +id: GO:0036165 +name: invasive growth in response to heat +namespace: biological_process +def: "The growth of colonies in filamentous chains of cells as a result of an increase in temperature." [GOC:di, PMID:22365851] +synonym: "invasive growth in response to elevated temperature" EXACT [PMID:22365851] +synonym: "invasive growth in response to high temperature" EXACT [PMID:22365851] +synonym: "invasive growth in response to temperature stimulus" BROAD [GOC:di] +is_a: GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +is_a: GO:0036267 ! invasive filamentous growth +created_by: bf +creation_date: 2012-03-27T11:23:03Z + +[Term] +id: GO:0036166 +name: phenotypic switching +namespace: biological_process +def: "A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues." [GOC:bf, GOC:di, PMID:12443899, PMID:22406749, PMID:8456504, Wikipedia:Phenotypic_switching] +comment: Mating type switching is not considered a type of phenotypic switching: for mating type switching, consider instead annotating to 'mating type switching ; GO:0007533'. +synonym: "phenotypic dimorphism" RELATED [Wikipedia:Phenotypic_switching] +is_a: GO:0009987 ! cellular process +created_by: bf +creation_date: 2012-03-27T01:31:28Z + +[Term] +id: GO:0036167 +name: phenotypic switching in response to host +namespace: biological_process +def: "A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns." [GOC:di, PMID:16696644, Wikipedia:Phenotypic_switching] +is_a: GO:0036166 ! phenotypic switching +is_a: GO:0075136 ! response to host +created_by: bf +creation_date: 2012-03-27T01:44:24Z + +[Term] +id: GO:0036168 +name: filamentous growth of a population of unicellular organisms in response to heat +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature." [GOC:di, PMID:17554048] +is_a: GO:0009408 ! response to heat +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: bf +creation_date: 2012-03-27T03:53:28Z + +[Term] +id: GO:0036169 +name: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2." [GOC:mw, PMID:620805, PMID:7028108] +xref: Reactome:R-HSA-2162195 "MHDB is decarboxylated to DMPhOH by MHDB decarboxylase" +is_a: GO:0016831 ! carboxy-lyase activity +created_by: bf +creation_date: 2012-03-27T04:47:47Z + +[Term] +id: GO:0036170 +name: filamentous growth of a population of unicellular organisms in response to starvation +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment." [GOC:di, PMID:17554048] +is_a: GO:0042594 ! response to starvation +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: bf +creation_date: 2012-03-27T03:53:28Z + +[Term] +id: GO:0036171 +name: filamentous growth of a population of unicellular organisms in response to chemical stimulus +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus." [GOC:di, PMID:17554048] +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +relationship: part_of GO:0042221 ! response to chemical +created_by: bf +creation_date: 2012-03-27T03:53:28Z + +[Term] +id: GO:0036172 +name: thiamine salvage +namespace: biological_process +def: "A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis." [PMID:15150256, PMID:16952958] +xref: MetaCyc:PWY-6896 +xref: MetaCyc:PWY-6897 +xref: MetaCyc:PWY-6898 +is_a: GO:0008655 ! pyrimidine-containing compound salvage +is_a: GO:0009228 ! thiamine biosynthetic process +created_by: bf +creation_date: 2012-03-29T10:31:05Z + +[Term] +id: GO:0036173 +name: thiosulfate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the inorganic anion thiosulfate, a sulfur oxide that has formula O3S2." [GOC:db, PMID:2188959] +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bf +creation_date: 2012-03-29T10:38:15Z + +[Term] +id: GO:0036174 +name: butane monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O." [GOC:dh, PMID:17526838, PMID:19383682] +synonym: "sBMO" RELATED [PMID:19383682] +synonym: "soluble butane monooxygenase" RELATED [PMID:19383682] +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-03-29T10:42:07Z + +[Term] +id: GO:0036175 +name: ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin." [EC:1.17.4.1, GOC:bf, GOC:pde, PMID:7476363] +xref: Reactome:R-HSA-111742 "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)" +xref: Reactome:R-HSA-8866405 "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)" +is_a: GO:0061731 ! ribonucleoside-diphosphate reductase activity +created_by: bf +creation_date: 2012-03-29T11:12:42Z + +[Term] +id: GO:0036176 +name: response to neutral pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:di, Wikipedia:PH] +is_a: GO:0009268 ! response to pH +created_by: bf +creation_date: 2012-03-29T01:38:00Z + +[Term] +id: GO:0036177 +name: filamentous growth of a population of unicellular organisms in response to pH +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:di, Wikipedia:PH] +is_a: GO:0009268 ! response to pH +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: bf +creation_date: 2012-03-29T01:43:04Z + +[Term] +id: GO:0036178 +name: filamentous growth of a population of unicellular organisms in response to neutral pH +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus." [GOC:di, PMID:6374461] +is_a: GO:0036176 ! response to neutral pH +is_a: GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +created_by: bf +creation_date: 2012-03-29T01:43:47Z + +[Term] +id: GO:0036179 +name: osteoclast maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes." [CL:0000092, GOC:pg] +synonym: "chondroclast maturation" RELATED [CL:0000092] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0036035 ! osteoclast development +created_by: bf +creation_date: 2012-03-29T02:04:00Z + +[Term] +id: GO:0036180 +name: filamentous growth of a population of unicellular organisms in response to biotic stimulus +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus." [GOC:di] +is_a: GO:0009607 ! response to biotic stimulus +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: bf +creation_date: 2012-03-30T04:12:40Z + +[Term] +id: GO:0036181 +name: protein localization to linear element +namespace: biological_process +def: "A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase." [GOC:mah, PMID:19756689] +synonym: "protein localisation to linear element" EXACT [GOC:mah] +is_a: GO:1903084 ! protein localization to condensed nuclear chromosome +created_by: bf +creation_date: 2012-03-30T04:14:17Z + +[Term] +id: GO:0036182 +name: asperthecin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans." [GOC:di] +synonym: "asperthecin metabolism" EXACT [GOC:bf] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: bf +creation_date: 2012-04-16T11:35:24Z + +[Term] +id: GO:0036183 +name: asperthecin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans." [GOC:di] +synonym: "asperthecin breakdown" EXACT [GOC:bf] +synonym: "asperthecin catabolism" EXACT [GOC:bf] +synonym: "asperthecin degradation" EXACT [GOC:bf] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0036182 ! asperthecin metabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: bf +creation_date: 2012-04-16T11:36:38Z + +[Term] +id: GO:0036184 +name: asperthecin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans." [GOC:di] +synonym: "asperthecin biosynthesis" EXACT [GOC:bf] +synonym: "asperthecin formation" EXACT [GOC:bf] +synonym: "asperthecin synthesis" EXACT [GOC:bf] +is_a: GO:0036182 ! asperthecin metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: bf +creation_date: 2012-04-16T11:36:56Z + +[Term] +id: GO:0036185 +name: 13-lipoxin reductase activity +namespace: molecular_function +def: "Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+." [GOC:mw, PMID:10837478] +xref: Reactome:R-HSA-2161844 "15k-LXA4 is reduced to dhk-LXA4 by PTGR1" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2012-04-16T02:28:19Z + +[Term] +id: GO:0036186 +name: early phagosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an early phagosome." [GOC:phg] +synonym: "early phagocytic vesicle membrane" EXACT [GOC:bf] +is_a: GO:0030670 ! phagocytic vesicle membrane +relationship: part_of GO:0032009 ! early phagosome +created_by: bf +creation_date: 2012-04-16T02:37:30Z + +[Term] +id: GO:0036187 +name: cell growth mode switching, budding to filamentous +namespace: biological_process +def: "The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans." [GOC:di] +synonym: "yeast to hyphal transition" RELATED [GOC:di] +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +created_by: bf +creation_date: 2012-04-18T11:32:57Z + +[Term] +id: GO:0036188 +name: abieta-7,13-dien-18-al dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+." [EC:1.2.1.74] +synonym: "abietadienal dehydrogenase" BROAD [EC:1.2.1.74] +xref: EC:1.2.1.74 +xref: KEGG_REACTION:R06357 +xref: MetaCyc:1.2.1.74-RXN +xref: RHEA:26225 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2012-04-18T01:46:19Z + +[Term] +id: GO:0036189 +name: abieta-7,13-diene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O." [EC:1.14.14.144] +synonym: "abietadiene hydroxylase" BROAD [EC:1.14.14.144] +xref: EC:1.14.14.144 +xref: KEGG_REACTION:R06351 +xref: MetaCyc:RXN-8507 +xref: RHEA:26217 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-19T10:57:05Z + +[Term] +id: GO:0036190 +name: indole-2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O." [EC:1.14.13.137, RHEA:31899] +xref: EC:1.14.14.153 +xref: KEGG_REACTION:R07403 +xref: RHEA:31899 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-19T11:24:48Z + +[Term] +id: GO:0036191 +name: indolin-2-one monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O." [EC:1.14.14.157, RHEA:31919] +synonym: "indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.14.157] +xref: EC:1.14.14.157 +xref: KEGG_REACTION:R07421 +xref: RHEA:31919 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-19T11:38:01Z + +[Term] +id: GO:0036192 +name: 3-hydroxyindolin-2-one monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O." [EC:1.14.13.139, RHEA:31927] +synonym: "3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)" EXACT [EC:1.14.14.109] +xref: EC:1.14.14.109 +xref: KEGG_REACTION:R07422 +xref: RHEA:31927 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-19T11:45:33Z + +[Term] +id: GO:0036193 +name: 2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O." [EC:1.14.13.140] +xref: EC:1.14.14.110 +xref: KEGG_REACTION:R07423 +xref: RHEA:31939 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-19T11:54:34Z + +[Term] +id: GO:0036194 +name: muscle cell projection +namespace: cellular_component +def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] +synonym: "muscle arm" NARROW [GOC:kmv] +synonym: "myocyte projection" EXACT [CL:0000187] +synonym: "myopodia" NARROW [GOC:kmv] +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: bf +creation_date: 2012-04-20T10:20:47Z + +[Term] +id: GO:0036195 +name: muscle cell projection membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] +is_a: GO:0031253 ! cell projection membrane +intersection_of: GO:0031253 ! cell projection membrane +intersection_of: part_of GO:0036194 ! muscle cell projection +relationship: part_of GO:0036194 ! muscle cell projection +created_by: bf +creation_date: 2012-04-20T10:21:51Z + +[Term] +id: GO:0036196 +name: zymosterol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol)." [GOC:yaf] +is_a: GO:0016125 ! sterol metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: bf +creation_date: 2012-04-20T10:27:06Z + +[Term] +id: GO:0036197 +name: zymosterol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol)." [GOC:yaf, MetaCyc:PWY-6074] +synonym: "zymosterol anabolism" EXACT [GOC:bf] +synonym: "zymosterol biosynthesis" EXACT [GOC:bf] +synonym: "zymosterol formation" EXACT [GOC:bf] +synonym: "zymosterol synthesis" EXACT [GOC:bf] +xref: MetaCyc:PWY-6074 +xref: UniPathway:UPA00770 +is_a: GO:0016126 ! sterol biosynthetic process +is_a: GO:0036196 ! zymosterol metabolic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process +created_by: bf +creation_date: 2012-04-20T10:28:46Z + +[Term] +id: GO:0036198 +name: dTMP salvage +namespace: biological_process +def: "Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis." [GOC:yaf, UniPathway:UPA00578] +synonym: "deoxythymidine monophosphate biosynthesis via salvage pathway" RELATED [GOC:yaf, PMID:5387459, UniPathway:UPA00578] +synonym: "dTMP biosynthesis via salvage pathway" RELATED [GOC:yaf, PMID:5387459, UniPathway:UPA00578] +xref: UniPathway:UPA00578 +is_a: GO:0006231 ! dTMP biosynthetic process +is_a: GO:0010139 ! pyrimidine deoxyribonucleotide salvage +created_by: bf +creation_date: 2012-04-20T10:33:28Z + +[Term] +id: GO:0036199 +name: cholest-4-en-3-one 26-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate." [EC:1.14.15.29] +xref: EC:1.14.15.29 +xref: KEGG_REACTION:R09859 +xref: RHEA:51564 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-20T02:03:05Z + +[Term] +id: GO:0036200 +name: 3-ketosteroid 9-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O." [EC:1.14.15.30] +synonym: "3-ketosteroid 9alpha-hydroxylase activity" EXACT [EC:1.14.13.142] +synonym: "KshAB activity" EXACT [EC:1.14.13.142] +xref: EC:1.14.15.30 +xref: KEGG_REACTION:R09860 +xref: RHEA:32199 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-20T02:09:47Z + +[Term] +id: GO:0036201 +name: ent-isokaurene C2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+." [EC:1.14.14.76] +xref: EC:1.14.14.76 +xref: KEGG_REACTION:R09861 +xref: RHEA:56336 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-20T02:21:33Z + +[Term] +id: GO:0036202 +name: ent-cassa-12,15-diene 11-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O." [EC:1.14.14.112] +synonym: "ent-cassadiene C11alpha-hydroxylase activity" EXACT [EC:1.14.14.112] +xref: EC:1.14.14.112 +xref: KEGG_REACTION:R09866 +xref: RHEA:31967 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-20T02:34:13Z + +[Term] +id: GO:0036203 +name: taxoid 14-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O." [EC:1.14.13.146] +xref: EC:1.14.13.146 +xref: KEGG_REACTION:R09867 +xref: RHEA:31971 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-20T02:40:54Z + +[Term] +id: GO:0036204 +name: abieta-7,13-dien-18-ol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O." [EC:1.14.14.145] +xref: EC:1.14.14.145 +xref: KEGG_REACTION:R06354 +xref: MetaCyc:RXN-12799 +xref: RHEA:26221 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-24T02:37:15Z + +[Term] +id: GO:0036205 +name: histone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells." [GOC:krc] +comment: This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells. +synonym: "histone protein catabolic process" EXACT [GOC:bf, GOC:jl] +is_a: GO:0044257 ! cellular protein catabolic process +created_by: bf +creation_date: 2012-04-24T04:48:48Z + +[Term] +id: GO:0036206 +name: regulation of histone gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein." [GOC:bf, GOC:krc] +comment: This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells. +synonym: "regulation of expression of histone-encoding gene" EXACT [GOC:bf] +is_a: GO:0010468 ! regulation of gene expression +created_by: bf +creation_date: 2012-04-24T05:01:28Z + +[Term] +id: GO:0036207 +name: positive regulation of histone gene expression +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein." [GOC:bf, GOC:krc] +comment: This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells. +synonym: "activation of histone gene expression" NARROW [GOC:bf] +synonym: "positive regulation of expression of histone-encoding gene" EXACT [GOC:bf] +synonym: "up-regulation of histone gene expression" EXACT [GOC:bf] +synonym: "upregulation of histone gene expression" EXACT [GOC:bf] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0036206 ! regulation of histone gene expression +created_by: bf +creation_date: 2012-04-25T09:27:42Z + +[Term] +id: GO:0036208 +name: negative regulation of histone gene expression +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein." [GOC:bf, GOC:krc] +comment: This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells. +synonym: "down-regulation of histone gene expression" EXACT [GOC:bf] +synonym: "downregulation of histone gene expression" EXACT [GOC:bf] +synonym: "inhibition of histone gene expression" NARROW [GOC:bf] +synonym: "negative regulation of expression of histone-encoding gene" EXACT [GOC:bf] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0036206 ! regulation of histone gene expression +created_by: bf +creation_date: 2012-04-25T09:29:43Z + +[Term] +id: GO:0036209 +name: 9beta-pimara-7,15-diene oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 NADPH + 3 H+ = 9beta-pimara-7,15-dien-19-oate + 3 NADP+ + 4 H2O. This is a three-step reaction: (a) 9beta-pimara-7,15-diene + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-ol + NADP+ + H2O, (b) 9beta-pimara-7,15-dien-19-ol + O2 + NADPH + H+ = 9neta-pimara-7,15-dien-19-al + NADP+ + 2 H2O, (c) 9beta-pimara-7,15-dien-19-al + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-oate + NADP+ + H2O." [EC:1.14.14.111] +xref: EC:1.14.14.111 +xref: KEGG_REACTION:R09865 +xref: RHEA:31951 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-04-25T11:11:55Z + +[Term] +id: GO:0036210 +name: protein modification process in other organism +namespace: biological_process +def: "The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] +synonym: "protein modification in other organism" EXACT [GOC:bf] +is_a: GO:0036211 ! protein modification process +is_a: GO:0044033 ! multi-organism metabolic process +created_by: bf +creation_date: 2012-04-26T01:29:29Z + +[Term] +id: GO:0036211 +name: protein modification process +namespace: biological_process +def: "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." [GOC:bf, GOC:jl] +synonym: "protein modification" EXACT [GOC:bf] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0043412 ! macromolecule modification +created_by: bf +creation_date: 2012-04-26T01:47:12Z + +[Term] +id: GO:0036212 +name: contractile ring maintenance +namespace: biological_process +def: "The process in which the contractile ring is maintained, typically in response to an internal or external cue." [GOC:mah, GOC:vw] +comment: This term can be used to annotate maintenance of either bacterial or fungal contractile rings. +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0043954 ! cellular component maintenance +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: bf +creation_date: 2012-04-26T02:57:39Z + +[Term] +id: GO:0036213 +name: contractile ring contraction +namespace: biological_process +def: "The process of an actomyosin ring getting smaller in diameter." [GOC:mah, GOC:vw] +comment: This term can be used to annotate contraction of either bacterial or fungal contractile rings. +is_a: GO:0032506 ! cytokinetic process +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: bf +creation_date: 2012-04-26T02:58:18Z + +[Term] +id: GO:0036214 +name: contractile ring localization +namespace: biological_process +def: "The process in which a contractile ring is assembled and/or maintained in a specific location." [GOC:mah, GOC:vw] +comment: This term can be used to annotate localization of either bacterial or fungal contractile rings. +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0051179 ! localization +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: bf +creation_date: 2012-04-26T02:58:50Z + +[Term] +id: GO:0036215 +name: response to stem cell factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus." [GOC:uh, PR:000009345] +synonym: "response to hematopoietic growth factor KL" EXACT [PR:000009345] +synonym: "response to KIT ligand" EXACT [PR:000009345] +synonym: "response to SCF" EXACT [PR:000009345] +synonym: "response to stem cell factor stimulus" EXACT [GOC:dos] +is_a: GO:0034097 ! response to cytokine +created_by: bf +creation_date: 2012-04-27T10:26:37Z + +[Term] +id: GO:0036216 +name: cellular response to stem cell factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus." [GOC:uh, PMID:18787413, PMID:7520444, PR:000009345] +synonym: "cellular response to hematopoietic growth factor KL" EXACT [PR:000009345] +synonym: "cellular response to KIT ligand" EXACT [PR:000009345] +synonym: "cellular response to KITLG" EXACT [PMID:18787413] +synonym: "cellular response to SCF" EXACT [PR:000009345] +is_a: GO:0036215 ! response to stem cell factor +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: bf +creation_date: 2012-04-27T10:30:53Z + +[Term] +id: GO:0036217 +name: dGTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate." [GOC:dgf, PMID:17090528, PMID:22531138, RHEA:28362] +synonym: "2'-deoxyguanosine 5'-triphosphate diphosphohydrolase" EXACT [KEGG_REACTION:R01855] +xref: KEGG_REACTION:R01855 +xref: RHEA:28362 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036218 +name: dTTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate." [GOC:dgf, PMID:22531138, RHEA:28534] +xref: EC:3.6.1.9 +xref: MetaCyc:RXN0-5107 +xref: RHEA:28534 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036219 +name: GTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + H2O = GMP + diphosphate." [GOC:dgf, PMID:22531138, RHEA:29391] +synonym: "GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase" EXACT [KEGG_REACTION:R00426] +synonym: "GTP diphosphohydrolase activity" EXACT [GOC:bf] +xref: KEGG_REACTION:R00426 +xref: RHEA:29391 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036220 +name: ITP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ITP + H2O = IMP + diphosphate." [GOC:dgf, PMID:17899088, PMID:22531138] +synonym: "inosine-5'-triphosphate pyrophosphohydrolase activity" EXACT [KEGG_REACTION:R00720] +xref: KEGG_REACTION:R00720 +xref: MetaCyc:RXN0-6382 +xref: Reactome:R-HSA-2509827 "ITPA hydrolyses ITP to IMP" +xref: RHEA:29399 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036221 +name: UTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: UTP + H2O = UMP + diphosphate." [GOC:dgf, PMID:17899088] +synonym: "uridine triphosphate pyrophosphohydrolase activity" EXACT [KEGG_REACTION:R00662] +xref: KEGG_REACTION:R00662 +xref: RHEA:29395 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036222 +name: XTP diphosphatase activity +namespace: molecular_function +alt_id: GO:0103024 +def: "Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate." [GOC:pz, PMID:16216582, PMID:22531138, RHEA:28610] +comment: While XTP is not produced by cells, deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP. XTPase contributes to the removal of these abnormal bases from the cellular pool of nucleotide triphosphates. +synonym: "hypoxanthine/xanthine dNTP pyrophosphatase" RELATED [EC:3.6.1.66] +synonym: "XTP pyrophosphohydrolase activity" EXACT [KEGG_REACTION:R02720] +synonym: "XTP/dITP diphosphatase" RELATED [EC:3.6.1.66] +synonym: "XTPase activity" EXACT [] +xref: EC:3.6.1.66 +xref: KEGG_REACTION:R02720 +xref: MetaCyc:RXN0-1603 +xref: MetaCyc:RXN0-5074 +xref: Reactome:R-HSA-2509831 "ITPA hydrolyses XTP to XMP" +xref: RHEA:28610 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19078 xsd:anyURI +created_by: bf +creation_date: 2012-05-08T01:47:59Z + +[Term] +id: GO:0036223 +name: cellular response to adenine starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine." [GOC:ai] +synonym: "cellular response to adenine deprivation" EXACT [GOC:bf] +is_a: GO:0009267 ! cellular response to starvation +created_by: bf +creation_date: 2012-05-09T02:26:52Z + +[Term] +id: GO:0036224 +name: pairing center +namespace: cellular_component +def: "A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment." [GOC:kmv, PMID:18597662] +synonym: "homolog recognition region" EXACT [GOC:kmv] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000794 ! condensed nuclear chromosome +created_by: bf +creation_date: 2012-05-09T02:28:53Z + +[Term] +id: GO:0036225 +name: cellular response to vitamin B1 starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine)." [GOC:al, Wikipedia:Thiamine] +synonym: "cellular response to thiamin starvation" EXACT [] +synonym: "cellular response to vitamin B1 deprivation" EXACT [GOC:bf] +is_a: GO:0009267 ! cellular response to starvation +created_by: bf +creation_date: 2012-05-09T02:35:55Z + +[Term] +id: GO:0036226 +name: obsolete mitotic cell cycle arrest in response to glucose starvation +namespace: biological_process +def: "OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose." [GOC:al, GOC:mah, PMID:958201] +comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G2 cell cycle arrest in response to glucose starvation' has been observed. +synonym: "cell cycle arrest in response to glucose starvation" BROAD [] +is_obsolete: true +created_by: bf +creation_date: 2012-05-09T02:43:22Z + +[Term] +id: GO:0036227 +name: mitotic G2 cell cycle arrest in response to glucose starvation +namespace: biological_process +def: "The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose." [GOC:al, GOC:mah, GOC:mtg_cell_cycle, PMID:958201] +is_a: GO:0071850 ! mitotic cell cycle arrest +created_by: bf +creation_date: 2012-05-09T02:45:49Z + +[Term] +id: GO:0036228 +name: protein localization to nuclear inner membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane." [GOC:dgf, PMID:16929305] +synonym: "protein targeting to INM" RELATED [PMID:16929305] +synonym: "protein targeting to nuclear inner membrane" RELATED [] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:0090435 ! protein localization to nuclear envelope +created_by: bf +creation_date: 2012-05-11T10:42:34Z + +[Term] +id: GO:0036230 +name: granulocyte activation +namespace: biological_process +def: "The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [CL:0000094, GOC:nhn] +is_a: GO:0002274 ! myeloid leukocyte activation +created_by: bf +creation_date: 2012-05-11T10:57:48Z + +[Term] +id: GO:0036234 +name: deglucuronidation +namespace: biological_process +def: "The removal of glucuronic acid from a conjugated substrate." [GOC:BHF, GOC:vk, PMID:22294686, PMID:8560473] +is_a: GO:0019585 ! glucuronate metabolic process +created_by: bf +creation_date: 2012-05-18T04:23:04Z + +[Term] +id: GO:0036235 +name: acyl deglucuronidation +namespace: biological_process +def: "The removal of glucuronic acid from an acyl-glucuronide." [GOC:BHF, GOC:vk, PMID:22294686] +is_a: GO:0036234 ! deglucuronidation +created_by: bf +creation_date: 2012-05-18T04:24:11Z + +[Term] +id: GO:0036236 +name: acyl glucuronidation +namespace: biological_process +def: "The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside)." [GOC:BHF, GOC:vk, PMID:12485951, PMID:22294686] +is_a: GO:0052695 ! cellular glucuronidation +created_by: bf +creation_date: 2012-05-18T04:26:25Z + +[Term] +id: GO:0036237 +name: acyl-glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate." [GOC:BHF, GOC:vk, PMID:22294686] +synonym: "acyl-glucuronide deglucuronidation activity" NARROW [PMID:22294686] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: bf +creation_date: 2012-05-18T04:32:25Z + +[Term] +id: GO:0036238 +name: gallate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate." [EC:1.13.11.57, PMID:16030014] +xref: EC:1.13.11.57 +xref: KEGG_REACTION:R09565 +xref: MetaCyc:GALLATE-DIOXYGENASE-RXN +xref: RHEA:28927 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +created_by: bf +creation_date: 2012-05-22T01:54:09Z + +[Term] +id: GO:0036239 +name: taxoid 7beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O." [EC:1.14.13.147] +xref: EC:1.14.13.147 +xref: KEGG_REACTION:R09868 +xref: MetaCyc:RXN-12885 +xref: RHEA:31975 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2012-05-22T02:13:21Z + +[Term] +id: GO:0036240 +name: septal periplasm +namespace: cellular_component +def: "The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi." [GOC:di, PMID:21564341] +synonym: "cell wall-enclosed septal periplasm" EXACT [GOC:di] +is_a: GO:0042597 ! periplasmic space +created_by: bf +creation_date: 2012-05-23T10:18:09Z + +[Term] +id: GO:0036241 +name: glutamate catabolic process to 4-hydroxybutyrate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate." [GOC:bf, MetaCyc:PWY-4321] +comment: In the catabolism of glutamate in mammals, succinate semialdehyde is converted to succinate (see GO:0006540). Plants can utilize an alternative route, converting succinic semialdehyde to 4-hydroxybutyrate using gamma-hydroxybutyrate dehydrogenase. +synonym: "glutamate degradation to 4-hydroxybutyrate" EXACT [MetaCyc:PWY-4321] +is_a: GO:0006538 ! glutamate catabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046459 ! short-chain fatty acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +relationship: has_part GO:0047577 ! 4-hydroxybutyrate dehydrogenase activity +created_by: bf +creation_date: 2012-05-23T02:17:05Z + +[Term] +id: GO:0036242 +name: glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase." [GOC:bf, MetaCyc:PWY-4321] +comment: While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants. +synonym: "glutamate degradation via gamma aminobutyrate transaminase activity" EXACT [MetaCyc:PWY-4321] +xref: MetaCyc:PWY-4321 +xref: MetaCyc:PWY3O-210 +is_a: GO:0006540 ! glutamate decarboxylation to succinate +relationship: has_part GO:0034386 ! 4-aminobutyrate:2-oxoglutarate transaminase activity +created_by: bf +creation_date: 2012-05-23T02:28:33Z + +[Term] +id: GO:0036243 +name: succinate-semialdehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+." [EC:1.2.1.79, GOC:bf] +comment: This function is similar to EC:1.2.1.24 [succinate-semialdehyde dehydrogenase (NAD+)], and EC:1.2.1.16 [succinate-semialdehyde dehydrogenase (NAD(P)+)], but is specific for NADP+. +synonym: "NADP-dependent succinate-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.79] +synonym: "succinate semialdehyde:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.79] +synonym: "succinic semialdehyde dehydrogenase (NADP+) activity" EXACT [EC:1.2.1.79] +synonym: "succinyl semialdehyde dehydrogenase (NADP+) activity" EXACT [EC:1.2.1.79] +is_a: GO:0009013 ! succinate-semialdehyde dehydrogenase [NAD(P)+] activity +created_by: bf +creation_date: 2012-05-23T02:47:52Z + +[Term] +id: GO:0036244 +name: cellular response to neutral pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:di, Wikipedia:PH] +is_a: GO:0036176 ! response to neutral pH +is_a: GO:0071467 ! cellular response to pH +created_by: bf +creation_date: 2012-05-28T10:21:03Z + +[Term] +id: GO:0036245 +name: cellular response to menadione +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position." [GOC:al, Wikipedia:Menadione] +synonym: "cellular response to vitamin K3" EXACT [GOC:al] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:1901655 ! cellular response to ketone +created_by: bf +creation_date: 2012-05-28T10:23:02Z + +[Term] +id: GO:0036246 +name: phytochelatin 2 import into vacuole +namespace: biological_process +def: "The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond." [GOC:al, PMID:19001374] +synonym: "PC2 import into vacuole" EXACT [GOC:al] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0071995 ! phytochelatin import into vacuole +created_by: bf +creation_date: 2012-05-31T11:09:20Z + +[Term] +id: GO:0036247 +name: phytochelatin 3 import into vacuole +namespace: biological_process +def: "The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond." [GOC:al, PMID:19001374] +synonym: "PC3 import into vacuole" EXACT [GOC:al] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0071995 ! phytochelatin import into vacuole +created_by: bf +creation_date: 2012-05-31T11:11:03Z + +[Term] +id: GO:0036248 +name: phytochelatin 4 import into vacuole +namespace: biological_process +def: "The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond." [GOC:al, PMID:19001374] +synonym: "PC4 import into vacuole" EXACT [GOC:al] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0071995 ! phytochelatin import into vacuole +created_by: bf +creation_date: 2012-05-31T11:12:08Z + +[Term] +id: GO:0036249 +name: cadmium ion import into vacuole +namespace: biological_process +def: "The directed movement of cadmium ions into the vacuole." [GOC:al] +synonym: "vacuolar cadmium import" RELATED [GOC:bf] +is_a: GO:0000041 ! transition metal ion transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: bf +creation_date: 2012-05-31T11:13:44Z + +[Term] +id: GO:0036250 +name: peroxisome transport along microtubule +namespace: biological_process +def: "The directed movement of a peroxisome along a microtubule, mediated by motor proteins." [GOC:pm, PMID:21525035] +is_a: GO:0072384 ! organelle transport along microtubule +created_by: bf +creation_date: 2012-05-31T03:09:09Z + +[Term] +id: GO:0036251 +name: positive regulation of transcription from RNA polymerase II promoter in response to salt stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:al] +is_a: GO:0061393 ! positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress +is_a: GO:0061416 ! regulation of transcription from RNA polymerase II promoter in response to salt stress +created_by: bf +creation_date: 2012-06-12T11:38:22Z + +[Term] +id: GO:0036252 +name: positive regulation of transcription from RNA polymerase II promoter in response to menadione +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position." [GOC:al] +synonym: "positive regulation of transcription from RNA polymerase II promoter in response to menadione stress" NARROW [GOC:al] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0036245 ! cellular response to menadione +created_by: bf +creation_date: 2012-06-12T11:40:58Z + +[Term] +id: GO:0036253 +name: response to amiloride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus." [GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0036270 ! response to diuretic +created_by: bf +creation_date: 2012-06-15T01:05:35Z + +[Term] +id: GO:0036254 +name: cellular response to amiloride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0036253 ! response to amiloride +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: bf +creation_date: 2012-06-15T01:06:16Z + +[Term] +id: GO:0036255 +name: response to methylamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus." [GOC:mah] +is_a: GO:0014075 ! response to amine +created_by: bf +creation_date: 2012-06-15T01:07:27Z + +[Term] +id: GO:0036256 +name: cellular response to methylamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus." [GOC:mah] +is_a: GO:0036255 ! response to methylamine +is_a: GO:0071418 ! cellular response to amine stimulus +created_by: bf +creation_date: 2012-06-15T01:08:00Z + +[Term] +id: GO:0036257 +name: multivesicular body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm." [GOC:sart, PMID:11566881] +synonym: "MVB organization" EXACT [GOC:bf] +is_a: GO:0007032 ! endosome organization +created_by: bf +creation_date: 2012-06-15T01:09:53Z + +[Term] +id: GO:0036258 +name: multivesicular body assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm." [GOC:sart, PMID:11566881, PMID:19571114] +synonym: "multivesicular body biogenesis" EXACT [PMID:19571114] +synonym: "MVB biogenesis" EXACT [PMID:19571114] +synonym: "MVB formation" EXACT [PMID:19571114] +is_a: GO:0036257 ! multivesicular body organization +is_a: GO:0070925 ! organelle assembly +created_by: bf +creation_date: 2012-06-15T01:12:24Z + +[Term] +id: GO:0036259 +name: aerobic raffinose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen." [GOC:al, PMID:10082789] +synonym: "aerobic raffinose breakdown" EXACT [GOC:bf] +synonym: "aerobic raffinose catabolism" EXACT [GOC:bf] +synonym: "aerobic raffinose degradation" EXACT [GOC:bf] +is_a: GO:0034484 ! raffinose catabolic process +created_by: bf +creation_date: 2012-06-15T01:14:51Z + +[Term] +id: GO:0036260 +name: RNA capping +namespace: biological_process +def: "The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts." [GOC:bf, GOC:krc, GOC:mah, PMID:18775984, PMID:27383794, PMID:29681497, PMID:30353673] +is_a: GO:0006396 ! RNA processing +created_by: bf +creation_date: 2012-06-15T02:10:23Z + +[Term] +id: GO:0036261 +name: 7-methylguanosine cap hypermethylation +namespace: biological_process +def: "Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation." [GOC:bf, GOC:BHF, GOC:krc, GOC:mah, GOC:rl, PMID:11983179, PMID:18775984] +synonym: "2,2,7-trimethylguanosine cap formation" EXACT [PMID:11983179] +synonym: "conversion of m(7)G to m(3)G" EXACT [PMID:11983179] +synonym: "hypermethylation of snoRNA cap" NARROW [GOC:bf, GOC:krc, GOC:mah] +synonym: "hypermethylation of snRNA cap" NARROW [GOC:bf, GOC:krc, GOC:mah] +synonym: "m(7)G cap hypermethylation" EXACT [GOC:bf] +synonym: "snoRNA capping" NARROW [GOC:rl] +synonym: "snRNA capping" NARROW [GOC:rl] +synonym: "TMG cap formation" EXACT [PMID:11983179] +is_a: GO:0001510 ! RNA methylation +is_a: GO:0036260 ! RNA capping +created_by: bf +creation_date: 2012-06-15T02:21:39Z + +[Term] +id: GO:0036262 +name: granulysin production +namespace: biological_process +def: "The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv, PR:000008119] +is_a: GO:0002440 ! production of molecular mediator of immune response +created_by: bf +creation_date: 2012-06-18T02:11:15Z + +[Term] +id: GO:0036263 +name: L-DOPA monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone." [GOC:sart, PMID:22120533] +is_a: GO:0004097 ! catechol oxidase activity +created_by: bf +creation_date: 2012-06-21T03:57:13Z + +[Term] +id: GO:0036264 +name: dopamine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone." [GOC:sart, PMID:22120533] +is_a: GO:0004097 ! catechol oxidase activity +created_by: bf +creation_date: 2012-06-21T04:11:30Z + +[Term] +id: GO:0036265 +name: RNA (guanine-N7)-methylation +namespace: biological_process +def: "The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule." [GOC:BHF, GOC:rl] +is_a: GO:0001510 ! RNA methylation +created_by: bf +creation_date: 2012-06-25T10:28:25Z + +[Term] +id: GO:0036266 +name: Cdc48p-Npl4p-Vms1p AAA ATPase complex +namespace: cellular_component +def: "A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p." [GOC:rn, PMID:21070972, PMID:21936843] +synonym: "Cdc48p-Npl4p-Vms1p complex" EXACT [GOC:rn] +synonym: "Vms1-Cdc48-Npl4 complex" EXACT [GOC:rn] +synonym: "Vms1p-Cdc48p-Npl4p complex" EXACT [GOC:rn] +is_a: GO:0098799 ! outer mitochondrial membrane protein complex +created_by: bf +creation_date: 2012-06-29T10:57:48Z + +[Term] +id: GO:0036267 +name: invasive filamentous growth +namespace: biological_process +def: "The growth of colonies in filamentous chains of cells into a substrate." [GOC:di, PMID:22276126] +synonym: "invasive growth" EXACT [GOC:di] +is_a: GO:0070783 ! growth of unicellular organism as a thread of attached cells +created_by: bf +creation_date: 2012-07-02T01:42:24Z + +[Term] +id: GO:0036268 +name: swimming +namespace: biological_process +def: "Self-propelled movement of an organism from one location to another through water, often by means of active fin movement." [GOC:cvs, PMID:22459995] +comment: For behavioral aspects of swimming, consider instead annotating to 'swimming behavior ; GO:0036269'. +is_a: GO:0040011 ! locomotion +created_by: bf +creation_date: 2012-07-04T10:12:24Z + +[Term] +id: GO:0036269 +name: swimming behavior +namespace: biological_process +def: "The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water." [GOC:cvs, PMID:16764679] +synonym: "swimming behaviour" EXACT [PMID:16764679] +is_a: GO:0007626 ! locomotory behavior +created_by: bf +creation_date: 2012-07-04T10:14:49Z + +[Term] +id: GO:0036270 +name: response to diuretic +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0042493 ! response to drug +created_by: bf +creation_date: 2012-07-09T01:26:24Z + +[Term] +id: GO:0036271 +name: response to methylphenidate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus." [GOC:hp, Wikipedia:Methylphenidate] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to MPD" EXACT [CHEBI:6887] +synonym: "response to MPH" EXACT [CHEBI:6887] +synonym: "response to ritalin" EXACT [CHEBI:6887] +is_a: GO:0042493 ! response to drug +is_a: GO:1901698 ! response to nitrogen compound +created_by: bf +creation_date: 2012-07-09T01:30:57Z + +[Term] +id: GO:0036272 +name: response to gemcitabine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas." [GOC:hp, Wikipedia:Gemcitabine] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to 2',2'-difluorodeoxycytidine" EXACT [CHEBI:175901] +synonym: "response to 2'-deoxy-2',2'-difluorocytidine" EXACT [CHEBI:175901] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2012-07-09T01:36:03Z + +[Term] +id: GO:0036273 +name: response to statin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to HMG-CoA reductase inhibitor" RELATED [CHEBI:35664] +synonym: "response to hydroxymethylglutaryl-CoA reductase inhibitor" RELATED [CHEBI:35664] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2012-07-09T01:54:01Z + +[Term] +id: GO:0036274 +name: response to lapatinib +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2012-07-09T02:02:26Z + +[Term] +id: GO:0036275 +name: response to 5-fluorouracil +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to 5-fluoropyrimidine-2,4(1H,3H)-dione" EXACT [CHEBI:46345] +synonym: "response to fluorouracil" EXACT [GOC:hp] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +created_by: bf +creation_date: 2012-07-09T02:08:23Z + +[Term] +id: GO:0036276 +name: response to antidepressant +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0042493 ! response to drug +created_by: bf +creation_date: 2012-07-09T02:12:44Z + +[Term] +id: GO:0036277 +name: response to anticonvulsant +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0042493 ! response to drug +created_by: bf +creation_date: 2012-07-09T02:40:12Z + +[Term] +id: GO:0036278 +name: positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen." [GOC:al, PMID:21118960] +is_a: GO:0006995 ! cellular response to nitrogen starvation +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0006995 ! cellular response to nitrogen starvation +intersection_of: positively_regulates GO:0006366 ! transcription by RNA polymerase II +created_by: bf +creation_date: 2012-07-11T11:02:55Z + +[Term] +id: GO:0036279 +name: positive regulation of protein export from nucleus in response to glucose starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose." [GOC:al, PMID:3541942] +is_a: GO:0042149 ! cellular response to glucose starvation +is_a: GO:0046827 ! positive regulation of protein export from nucleus +created_by: bf +creation_date: 2012-07-11T11:05:20Z + +[Term] +id: GO:0036280 +name: cellular response to L-canavanine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group." [GOC:al] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901354 ! response to L-canavanine +created_by: bf +creation_date: 2012-07-11T11:09:37Z + +[Term] +id: GO:0036281 +name: coflocculation +namespace: biological_process +alt_id: GO:0036282 +def: "The non-sexual aggregation between single-celled organisms of different species." [GOC:al, PMID:11472912, PMID:11693916] +synonym: "co-flocculation" EXACT [PMID:10689163] +synonym: "coflocculation via lectin-mannose interaction" NARROW [PMID:11693916] +synonym: "coflocculation via protein-carbohydrate interaction" NARROW [] +is_a: GO:0044419 ! interspecies interaction between organisms +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18785 xsd:anyURI +created_by: bf +creation_date: 2012-07-11T01:30:40Z + +[Term] +id: GO:0036283 +name: obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress." [GOC:al, PMID:9585505] +comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus. +synonym: "positive regulation of transcription factor import into nucleus in response to hydrogen peroxide" RELATED [GOC:al] +is_obsolete: true +created_by: bf +creation_date: 2012-07-11T01:46:10Z + +[Term] +id: GO:0036284 +name: tubulobulbar complex +namespace: cellular_component +def: "Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes." [GOC:sl, PMID:22510523] +synonym: "TBC" EXACT [GOC:sl, PMID:22510523] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2012-07-16T10:26:35Z + +[Term] +id: GO:0036285 +name: SAGA complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof." [GOC:mah, PMID:10637607, PMID:22456315] +synonym: "SAGA complex formation" EXACT [GOC:bf] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: bf +creation_date: 2012-07-16T10:30:00Z + +[Term] +id: GO:0036286 +name: eisosome filament +namespace: cellular_component +def: "A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1." [GOC:vw, PMID:21900489, PMID:23722945] +synonym: "linear eisosome" EXACT [GOC:vw] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030863 ! cortical cytoskeleton +relationship: part_of GO:0032126 ! eisosome +created_by: bf +creation_date: 2012-07-16T10:52:24Z + +[Term] +id: GO:0036287 +name: response to iloperidone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:0071867 ! response to monoamine +is_a: GO:0097332 ! response to antipsychotic drug +is_a: GO:1901654 ! response to ketone +created_by: bf +creation_date: 2012-07-16T05:01:29Z + +[Term] +id: GO:0036288 +name: response to ximelagatran +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061476 ! response to anticoagulant +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2012-07-16T05:03:56Z + +[Term] +id: GO:0036289 +name: peptidyl-serine autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein." [GOC:pm] +synonym: "serine autophosphorylation" EXACT [GOC:bf] +is_a: GO:0018105 ! peptidyl-serine phosphorylation +is_a: GO:0046777 ! protein autophosphorylation +created_by: bf +creation_date: 2012-07-18T10:24:32Z + +[Term] +id: GO:0036290 +name: protein trans-autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer." [GOC:jsg, PMID:20516151] +synonym: "trans-autophosphorylation" EXACT [GOC:jsg] +is_a: GO:0046777 ! protein autophosphorylation +created_by: bf +creation_date: 2012-07-18T10:27:06Z + +[Term] +id: GO:0036291 +name: protein cis-autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own amino acid residues." [GOC:jsg, PMID:9201908] +synonym: "cis-autophosphorylation" EXACT [GOC:jsg] +is_a: GO:0046777 ! protein autophosphorylation +created_by: bf +creation_date: 2012-07-18T10:27:06Z + +[Term] +id: GO:0036292 +name: DNA rewinding +namespace: biological_process +def: "The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA." [PMID:21078962, PMID:22704558, PMID:22705370, PMID:22759634] +synonym: "DNA annealing" RELATED [GOC:sp] +synonym: "RPA-dependent DNA rewinding" NARROW [PMID:21078962] +synonym: "single-stranded DNA bubble rewinding" NARROW [PMID:18974355] +is_a: GO:0032392 ! DNA geometric change +relationship: has_part GO:0000733 ! DNA strand renaturation +created_by: bf +creation_date: 2012-07-18T10:43:41Z + +[Term] +id: GO:0036293 +name: response to decreased oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al] +comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'. +synonym: "response to lowered oxygen levels" EXACT [GOC:bf] +is_a: GO:0070482 ! response to oxygen levels +created_by: bf +creation_date: 2012-07-20T01:05:46Z + +[Term] +id: GO:0036294 +name: cellular response to decreased oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al] +comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'cellular response to hypoxia ; GO:0071456'. +synonym: "cellular response to lowered oxygen levels" EXACT [GOC:bf] +is_a: GO:0036293 ! response to decreased oxygen levels +is_a: GO:0071453 ! cellular response to oxygen levels +created_by: bf +creation_date: 2012-07-20T01:08:40Z + +[Term] +id: GO:0036295 +name: cellular response to increased oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen." [GOC:al] +comment: This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'cellular response to hyperoxia ; GO:0071455'. +synonym: "cellular response to raised oxygen levels" EXACT [GOC:bf] +is_a: GO:0036296 ! response to increased oxygen levels +is_a: GO:0071453 ! cellular response to oxygen levels +created_by: bf +creation_date: 2012-07-20T01:09:39Z + +[Term] +id: GO:0036296 +name: response to increased oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen." [GOC:al] +comment: This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'response to hyperoxia ; GO:0055093. +synonym: "response to raised oxygen levels" EXACT [GOC:bf] +is_a: GO:0070482 ! response to oxygen levels +created_by: bf +creation_date: 2012-07-20T01:10:48Z + +[Term] +id: GO:0036297 +name: interstrand cross-link repair +namespace: biological_process +def: "Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication." [GOC:vw, PMID:16464006, PMID:22064477] +synonym: "ICL repair" EXACT [PMID:20658649] +is_a: GO:0006281 ! DNA repair +created_by: bf +creation_date: 2012-08-07T11:05:19Z + +[Term] +id: GO:0036298 +name: recombinational interstrand cross-link repair +namespace: biological_process +def: "Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA." [GOC:vw, PMID:20658649] +synonym: "recombination-dependent interstrand cross-link repair" EXACT [GOC:vw] +is_a: GO:0000725 ! recombinational repair +is_a: GO:0036297 ! interstrand cross-link repair +created_by: bf +creation_date: 2012-08-07T11:11:59Z + +[Term] +id: GO:0036299 +name: non-recombinational interstrand cross-link repair +namespace: biological_process +def: "Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination." [GOC:vw, PMID:11154259, PMID:22064477] +synonym: "recombination-independent ICL repair" EXACT [GOC:vw] +synonym: "recombination-independent interstrand cross-link repair" EXACT [GOC:vw] +is_a: GO:0000726 ! non-recombinational repair +is_a: GO:0036297 ! interstrand cross-link repair +created_by: bf +creation_date: 2012-08-07T11:11:59Z + +[Term] +id: GO:0036300 +name: B cell receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell." [GOC:add, GOC:amm] +synonym: "B cell receptor uptake of antigen" NARROW [PMID:10996020] +synonym: "BCR endocytosis" EXACT [GOC:bf] +synonym: "BCR receptor internalization" EXACT [GOC:amm] +is_a: GO:0031623 ! receptor internalization +created_by: bf +creation_date: 2012-08-07T11:24:20Z + +[Term] +id: GO:0036301 +name: macrophage colony-stimulating factor production +namespace: biological_process +def: "The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:vk] +synonym: "M-CSF production" EXACT [GOC:vk] +is_a: GO:0001816 ! cytokine production +created_by: bf +creation_date: 2012-08-07T14:07:13Z + +[Term] +id: GO:0036302 +name: atrioventricular canal development +namespace: biological_process +def: "The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle." [GOC:BHF, GOC:gr, PMID:14701881, UBERON:0002087, ZFA:0001315] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007507 ! heart development +created_by: bf +creation_date: 2012-08-08T09:55:37Z + +[Term] +id: GO:0036303 +name: lymph vessel morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph." [GOC:BHF, GOC:gr, PMID:18093989] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0001945 ! lymph vessel development +created_by: bf +creation_date: 2012-08-08T10:08:47Z + +[Term] +id: GO:0036304 +name: umbilical cord morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0061027 ! umbilical cord development +created_by: bf +creation_date: 2012-08-08T10:12:11Z + +[Term] +id: GO:0036305 +name: ameloblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ." [CL:0000059] +is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation +created_by: bf +creation_date: 2012-08-08T13:49:15Z + +[Term] +id: GO:0036306 +name: embryonic heart tube elongation +namespace: biological_process +def: "The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:BHF, GOC:gr, PMID:15901664] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035050 ! embryonic heart tube development +created_by: bf +creation_date: 2012-08-08T13:54:37Z + +[Term] +id: GO:0036307 +name: 23S rRNA (adenine(2030)-N(6))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA." [GOC:imk, PMID:22847818] +is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity +created_by: bf +creation_date: 2012-08-08T14:15:48Z + +[Term] +id: GO:0036308 +name: 16S rRNA (guanine(1516)-N(2))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine." [GOC:imk, PMID:22079366] +is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity +created_by: bf +creation_date: 2012-08-08T14:17:44Z + +[Term] +id: GO:0036309 +name: protein localization to M-band +namespace: biological_process +def: "Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere." [GOC:BHF, GOC:rl, PMID:18782775] +synonym: "cellular protein localization to M-band" EXACT [GOC:rl] +synonym: "protein localization to M disc" EXACT [GOC:rl] +synonym: "protein localization to M line" NARROW [GOC:rl] +synonym: "protein localization to mesophragma" EXACT [GOC:rl] +is_a: GO:0033365 ! protein localization to organelle +created_by: bf +creation_date: 2012-08-14T14:02:58Z + +[Term] +id: GO:0036310 +name: annealing helicase activity +namespace: molecular_function +def: "Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA)." [GOC:bf, GOC:sp, PMID:21078962, PMID:22704558, PMID:22705370, PMID:22759634] +synonym: "annealing activity" BROAD [GOC:bf] +synonym: "ATP-dependent DNA annealing activity" RELATED [GOC:sp] +synonym: "nucleoside-triphosphatase activity involved in DNA annealing" EXACT [GOC:bf] +is_a: GO:0017111 ! nucleoside-triphosphatase activity +is_a: GO:0097617 ! annealing activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +intersection_of: GO:0017111 ! nucleoside-triphosphatase activity +intersection_of: part_of GO:0000733 ! DNA strand renaturation +relationship: part_of GO:0000733 ! DNA strand renaturation +created_by: bf +creation_date: 2012-08-14T15:24:29Z + +[Term] +id: GO:0036311 +name: chitin disaccharide deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate." [EC:3.5.1.105, GOC:imk] +comment: In contrast to EC:3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide. +synonym: "chitin oligosaccharide amidohydrolase activity" EXACT [EC:3.5.1.105] +synonym: "chitin oligosaccharide deacetylase activity" EXACT [EC:3.5.1.105] +synonym: "chitobiose amidohydrolase activity" EXACT [EC:3.5.1.105] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: bf +creation_date: 2012-08-15T15:18:09Z + +[Term] +id: GO:0036312 +name: phosphatidylinositol 3-kinase regulatory subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location." [GOC:bf, PMID:20505341] +synonym: "p85 binding" RELATED [PMID:10627473, PMID:20505341] +synonym: "PI3K regulatory subunit binding" EXACT [GOC:bf] +is_a: GO:0043548 ! phosphatidylinositol 3-kinase binding +created_by: bf +creation_date: 2012-08-16T10:58:45Z + +[Term] +id: GO:0036313 +name: phosphatidylinositol 3-kinase catalytic subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring." [GOC:bf, PMID:17475214] +synonym: "p110 binding" RELATED [PMID:17475214] +synonym: "PI3K catalytic subunit binding" EXACT [GOC:bf] +is_a: GO:0019900 ! kinase binding +is_a: GO:0043548 ! phosphatidylinositol 3-kinase binding +created_by: bf +creation_date: 2012-08-16T10:58:45Z + +[Term] +id: GO:0036314 +name: response to sterol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus." [GOC:bf] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: bf +creation_date: 2012-08-21T14:50:14Z + +[Term] +id: GO:0036315 +name: cellular response to sterol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus." [GOC:bf] +is_a: GO:0036314 ! response to sterol +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: bf +creation_date: 2012-08-21T14:51:21Z + +[Term] +id: GO:0036316 +name: SREBP-SCAP complex retention in endoplasmic reticulum +namespace: biological_process +def: "Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER." [GOC:bf, PMID:16525117] +comment: Consider also annotating to the cellular component term: SREBP-SCAP-Insig complex ; GO:0032937. +is_a: GO:0035437 ! maintenance of protein localization in endoplasmic reticulum +is_a: GO:2000639 ! negative regulation of SREBP signaling pathway +relationship: part_of GO:0036315 ! cellular response to sterol +created_by: bf +creation_date: 2012-08-21T14:53:08Z + +[Term] +id: GO:0036317 +name: tyrosyl-RNA phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis." [GOC:bf, GOC:sp, PMID:21408223, PMID:22908287] +synonym: "unlinkase activity" EXACT [PMID:21408223] +synonym: "uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity" EXACT [PMID:21408223] +synonym: "VPg unlinkase activity" EXACT [GOC:sp, PMID:21408223, PMID:22908287] +synonym: "Y-pUpN PDE activity" EXACT [PMID:21408223] +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: bf +creation_date: 2012-08-30T11:08:04Z + +[Term] +id: GO:0036318 +name: peptide pheromone receptor activity +namespace: molecular_function +def: "Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity." [GOC:al] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +is_a: GO:0016503 ! pheromone receptor activity +created_by: bf +creation_date: 2012-08-30T16:45:14Z + +[Term] +id: GO:0036319 +name: mating-type M-factor pheromone receptor activity +namespace: molecular_function +def: "Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus." [GOC:al, PMID:7941744] +synonym: "M-factor mating pheromone receptor activity" EXACT [] +synonym: "M-factor receptor activity" EXACT [] +is_a: GO:0004932 ! mating-type factor pheromone receptor activity +is_a: GO:0036318 ! peptide pheromone receptor activity +created_by: bf +creation_date: 2012-08-30T16:51:12Z + +[Term] +id: GO:0036320 +name: mating-type P-factor pheromone receptor activity +namespace: molecular_function +def: "Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus." [GOC:al, PMID:8314086, PMID:886120] +synonym: "P-factor mating pheromone receptor activity" EXACT [2] +synonym: "P-factor receptor activity" EXACT [] +is_a: GO:0004932 ! mating-type factor pheromone receptor activity +is_a: GO:0036318 ! peptide pheromone receptor activity +created_by: bf +creation_date: 2012-08-30T16:55:30Z + +[Term] +id: GO:0036321 +name: ghrelin secretion +namespace: biological_process +def: "The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone." [GOC:cjm, PMID:14610293, Wikipedia:Ghrelin] +synonym: "pancreatic ghrelin secretion" NARROW [GOC:cjm] +is_a: GO:0015893 ! drug transport +is_a: GO:0030072 ! peptide hormone secretion +created_by: bf +creation_date: 2012-09-04T14:16:43Z + +[Term] +id: GO:0036322 +name: pancreatic polypeptide secretion +namespace: biological_process +def: "The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas." [GOC:cjm, PMID:12730894, Wikipedia:Pancreatic_polypeptide] +synonym: "PP secretion" NARROW [GOC:cjm] +is_a: GO:0030072 ! peptide hormone secretion +created_by: bf +creation_date: 2012-09-04T14:39:03Z + +[Term] +id: GO:0036323 +name: vascular endothelial growth factor receptor-1 signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:uh, PR:000007563, Wikipedia:FLT1, Wikipedia:VEGF_receptors] +synonym: "FLT1 signaling pathway" EXACT [GOC:uh, PR:000007563] +synonym: "VEGFR-1 signaling pathway" EXACT [PR:000007563, Reactome:R-HSA-194311, Wikipedia:VEGF_receptors] +synonym: "VEGFR1 signaling pathway" EXACT [Reactome:R-HSA-194311] +is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +created_by: bf +creation_date: 2012-09-04T15:11:21Z + +[Term] +id: GO:0036324 +name: vascular endothelial growth factor receptor-2 signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:uh, PMID:12967471, PR:000002112, Wikipedia:Kinase_insert_domain_receptor, Wikipedia:VEGF_receptors] +synonym: "FLK-1 signaling pathway" EXACT [PR:000002112] +synonym: "KDR signaling pathway" EXACT [GOC:uh, PR:000002112, Wikipedia:Kinase_insert_domain_receptor] +synonym: "VEGFR-2 signaling pathway" EXACT [PR:000002112, Reactome:R-HSA-194310, Wikipedia:Kinase_insert_domain_receptor, Wikipedia:VEGF_receptors] +synonym: "VEGFR2 signaling pathway" EXACT [Reactome:R-HSA-194310] +is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +created_by: bf +creation_date: 2012-09-04T15:15:40Z + +[Term] +id: GO:0036325 +name: vascular endothelial growth factor receptor-3 signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:uh, PR:000007565, Wikipedia:VEGF_receptors, Wikipedia:VEGFR3] +synonym: "FLT4 signaling pathway" EXACT [GOC:uh, PR:000007565] +synonym: "VEGFR-3 signaling pathway" EXACT [Reactome:R-HSA-194308, Wikipedia:VEGF_receptors] +synonym: "VEGFR3 signaling pathway" EXACT [Reactome:R-HSA-194310, Wikipedia:VEGFR3] +is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +created_by: bf +creation_date: 2012-09-04T15:25:13Z + +[Term] +id: GO:0036326 +name: VEGF-A-activated receptor activity +namespace: molecular_function +def: "Combining with vascular endothelial growth factor A (VEGF-A) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:signaling, PR:000017284, Wikipedia:VEGF-A] +synonym: "vascular endothelial growth factor A-activated receptor activity" EXACT [GOC:bf, PR:000017284] +is_a: GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2012-09-04T15:33:19Z + +[Term] +id: GO:0036327 +name: VEGF-B-activated receptor activity +namespace: molecular_function +def: "Combining with vascular endothelial growth factor B (VEGF-B) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:signaling, PR:000003096, Wikipedia:VEGF-B] +synonym: "vascular endothelial growth factor B-activated receptor activity" EXACT [GOC:bf, PR:000003096] +is_a: GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2012-09-04T15:36:05Z + +[Term] +id: GO:0036328 +name: VEGF-C-activated receptor activity +namespace: molecular_function +def: "Combining with vascular endothelial growth factor C (VEGF-C) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:signaling, PR:000017285, Wikipedia:VEGF-C] +synonym: "vascular endothelial growth factor C-activated receptor activity" EXACT [GOC:bf, PR:000017285] +synonym: "VEGFC-activated receptor activity" EXACT [PR:000017285] +is_a: GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2012-09-04T15:37:17Z + +[Term] +id: GO:0036329 +name: VEGF-D-activated receptor activity +namespace: molecular_function +def: "Combining with vascular endothelial growth factor D (VEGF-D) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:signaling, PR:000007520, Wikipedia:VEGF-D] +synonym: "C-fos induced growth factor receptor activity" EXACT [PR:000007520, Wikipedia:VEGF-D] +synonym: "vascular endothelial growth factor D-activated receptor activity" EXACT [GOC:bf, PR:000007520] +synonym: "VEGFD-activated receptor activity" EXACT [PR:000017285] +is_a: GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2012-09-04T15:38:31Z + +[Term] +id: GO:0036330 +name: VEGF-E-activated receptor activity +namespace: molecular_function +def: "Combining with vascular endothelial growth factor E (VEGF-E) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:signaling, PMID:19909239] +synonym: "vascular endothelial growth factor E-activated receptor activity" EXACT [PMID:19909239] +is_a: GO:0005021 ! vascular endothelial growth factor-activated receptor activity +relationship: part_of GO:0036324 ! vascular endothelial growth factor receptor-2 signaling pathway +created_by: bf +creation_date: 2012-09-04T15:41:31Z + +[Term] +id: GO:0036331 +name: avascular cornea development in camera-type eye +namespace: biological_process +def: "The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees." [GOC:uh, PMID:16849433, PMID:17051153] +synonym: "avascular cornea development" EXACT [GOC:bf] +is_a: GO:0061303 ! cornea development in camera-type eye +created_by: bf +creation_date: 2012-09-05T09:07:14Z + +[Term] +id: GO:0036332 +name: placental growth factor-activated receptor activity +namespace: molecular_function +def: "Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:uh, PMID:12871269, PMID:7929268, PR:000012605, Wikipedia:Placental_growth_factor] +synonym: "placental growth factor receptor activity" EXACT [GOC:bf] +synonym: "PlGF receptor activity" RELATED [PMID:12871269] +synonym: "PlGF-activated receptor activity" EXACT [GOC:uh, PMID:12871269] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +relationship: part_of GO:0036323 ! vascular endothelial growth factor receptor-1 signaling pathway +created_by: bf +creation_date: 2012-09-05T09:34:37Z + +[Term] +id: GO:0036333 +name: hepatocyte homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874] +is_a: GO:0048872 ! homeostasis of number of cells +created_by: bf +creation_date: 2012-09-05T10:17:07Z + +[Term] +id: GO:0036334 +name: epidermal stem cell homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529] +is_a: GO:0048872 ! homeostasis of number of cells +created_by: bf +creation_date: 2012-09-05T10:21:23Z + +[Term] +id: GO:0036335 +name: intestinal stem cell homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells." [GOC:nhn, PMID:22042863] +is_a: GO:0048872 ! homeostasis of number of cells +created_by: bf +creation_date: 2012-09-05T10:23:41Z + +[Term] +id: GO:0036336 +name: dendritic cell migration +namespace: biological_process +def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990] +is_a: GO:0050900 ! leukocyte migration +created_by: bf +creation_date: 2012-09-05T10:24:46Z + +[Term] +id: GO:0036337 +name: Fas signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily." [GOC:nhn, PMID:12040174, Wikipedia:Fas_receptor] +synonym: "Apo-1 signaling pathway" EXACT [PMID:12040174] +synonym: "CD95 signaling pathway" EXACT [PMID:12040174] +synonym: "FAS ligand-Fas signaling pathway" NARROW [PMID:12040174] +synonym: "Fas receptor signaling pathway" EXACT [Wikipedia:Fas_receptor] +synonym: "Fas-FasL signaling pathway" NARROW [GOC:bf] +synonym: "FasL signaling pathway" RELATED [Wikipedia:Fas_ligand] +synonym: "FasR signaling pathway" EXACT [Wikipedia:Fas_receptor] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2012-09-05T10:28:11Z + +[Term] +id: GO:0036338 +name: viral membrane +namespace: cellular_component +def: "The lipid bilayer of a virion, a complete fully infectious extracellular virus particle." [GOC:bm] +is_a: GO:0044423 ! virion part +created_by: bf +creation_date: 2012-09-07T13:28:21Z + +[Term] +id: GO:0036339 +name: lymphocyte adhesion to endothelial cell of high endothelial venule +namespace: biological_process +def: "The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream." [CL:0000542, CL:0002652, GOC:nhn, PMID:19339990, PMID:7679710, Wikipedia:High_endothelial_venules] +comment: For the transition of leukocytes from rolling to adhered, consider instead annotating to 'leukocyte adhesive activation ; GO:0050902'. +synonym: "lymphocyte adhesion to HEV cell" EXACT [PMID:7679710, Wikipedia:High_endothelial_venules] +synonym: "lymphocyte adhesion to high endothelial venule" EXACT [GOC:nhn] +is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell +created_by: bf +creation_date: 2012-09-10T16:00:23Z + +[Term] +id: GO:0036340 +name: chitin-based cuticle sclerotization by biomineralization +namespace: biological_process +def: "The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate." [GOC:sart] +synonym: "chitin-based cuticle hardening by biomineralisation" EXACT [GOC:bf] +is_a: GO:0007593 ! chitin-based cuticle sclerotization +is_a: GO:0031214 ! biomineral tissue development +created_by: bf +creation_date: 2012-09-11T13:50:04Z + +[Term] +id: GO:0036341 +name: chitin-based cuticle sclerotization by protein cross-linking +namespace: biological_process +def: "The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle." [GOC:bf, GOC:sart] +synonym: "chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning" NARROW [GOC:bf, GOC:dos, GOC:sart] +is_a: GO:0007593 ! chitin-based cuticle sclerotization +created_by: bf +creation_date: 2012-09-11T13:51:46Z + +[Term] +id: GO:0036342 +name: post-anal tail morphogenesis +namespace: biological_process +def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: bf +creation_date: 2012-09-11T13:54:49Z + +[Term] +id: GO:0036343 +name: psychomotor behavior +namespace: biological_process +def: "The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument." [GOC:nhn, GOC:pr, PMID:17159989, Wikipedia:Psychomotor_learning] +is_a: GO:0061744 ! motor behavior +created_by: bf +creation_date: 2012-09-11T14:32:06Z + +[Term] +id: GO:0036344 +name: platelet morphogenesis +namespace: biological_process +def: "Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation." [CL:0000233, GOC:BHF, GOC:vk] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +created_by: bf +creation_date: 2012-09-11T15:15:35Z + +[Term] +id: GO:0036345 +name: platelet maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation." [CL:0000233, GOC:BHF, GOC:vk] +is_a: GO:0048469 ! cell maturation +created_by: bf +creation_date: 2012-09-11T15:23:11Z + +[Term] +id: GO:0036346 +name: cellular response to L-cysteine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration." [GOC:al] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1901367 ! response to L-cysteine +created_by: bf +creation_date: 2012-09-18T14:21:54Z + +[Term] +id: GO:0036348 +name: hydantoin racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin." [EC:5.1.99.5, InterPro:IPR015942] +xref: EC:5.1.99.5 +xref: KEGG_REACTION:R09704 +xref: MetaCyc:RXN-9781 +is_a: GO:0016854 ! racemase and epimerase activity +created_by: bf +creation_date: 2012-09-19T10:47:56Z + +[Term] +id: GO:0036349 +name: galactose-specific flocculation +namespace: biological_process +alt_id: GO:0098611 +def: "The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other." [GOC:vw, PMID:22098069] +synonym: "cell-cell adhesion involved in galactose-specific flocculation" EXACT [] +is_a: GO:0000128 ! flocculation +relationship: has_part GO:0005534 ! galactose binding +created_by: bf +creation_date: 2012-09-19T10:56:16Z + +[Term] +id: GO:0036350 +name: mannose-specific flocculation +namespace: biological_process +alt_id: GO:0098612 +def: "The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other." [GOC:vw, PMID:9851992] +synonym: "cell-cell adhesion involved in mannose-specific flocculation" EXACT [] +is_a: GO:0000128 ! flocculation +relationship: has_part GO:0005537 ! mannose binding +created_by: bf +creation_date: 2012-09-19T10:57:34Z + +[Term] +id: GO:0036351 +name: histone H2A-K13 ubiquitination +namespace: biological_process +def: "The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin." [GOC:sp, PMID:22713238, PMID:22980979] +synonym: "histone H2A ubiquitination (H2A-K13)" EXACT [GOC:sp] +is_a: GO:0033522 ! histone H2A ubiquitination +created_by: bf +creation_date: 2012-09-19T11:48:05Z + +[Term] +id: GO:0036352 +name: histone H2A-K15 ubiquitination +namespace: biological_process +def: "The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin." [GOC:sp, PMID:22713238, PMID:22980979] +synonym: "histone H2A ubiquitination (H2A-K15)" EXACT [GOC:sp] +is_a: GO:0033522 ! histone H2A ubiquitination +created_by: bf +creation_date: 2012-09-19T11:49:03Z + +[Term] +id: GO:0036353 +name: histone H2A-K119 monoubiquitination +namespace: biological_process +def: "The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms." [GOC:sp, PMID:15386022] +synonym: "histone H2A monoubiquitination (H2A-K119)" EXACT [GOC:sp] +is_a: GO:0035518 ! histone H2A monoubiquitination +created_by: bf +creation_date: 2012-09-19T11:52:25Z + +[Term] +id: GO:0036354 +name: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+." [GOC:crds, InterPro:IPR005903, MetaCyc:RXN-8787, PMID:8437569] +xref: MetaCyc:RXN-8787 +is_a: GO:0016491 ! oxidoreductase activity +relationship: part_of GO:0030494 ! bacteriochlorophyll biosynthetic process +created_by: bf +creation_date: 2012-09-19T14:46:31Z + +[Term] +id: GO:0036355 +name: 2-iminoacetate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+." [EC:4.1.99.19, GOC:crds, MetaCyc:RXN-11319, PMID:17403671] +xref: EC:4.1.99.19 +xref: MetaCyc:RXN-11319 +xref: RHEA:26361 +is_a: GO:0016830 ! carbon-carbon lyase activity +relationship: part_of GO:0009228 ! thiamine biosynthetic process +created_by: bf +creation_date: 2012-09-19T14:52:51Z + +[Term] +id: GO:0036356 +name: cyclic 2,3-diphosphoglycerate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate." [GOC:crds, PMID:2226838, PMID:8320225, PMID:9811660] +comment: This reaction is the intramolecular cyclization of 2,3-diphosphoglycerate to cyclic 2,3-diphosphoglycerate and is the second step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG). +synonym: "cDPGS activity" EXACT [PMID:9811660] +synonym: "CPGS activity" EXACT [GOC:bf] +xref: EC:4.6.1 +is_a: GO:0009975 ! cyclase activity +relationship: part_of GO:1901369 ! cyclic 2,3-bisphospho-D-glycerate biosynthetic process +created_by: bf +creation_date: 2012-09-19T14:59:19Z + +[Term] +id: GO:0036357 +name: 2-phosphoglycerate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP." [GOC:bf, InterPro:IPR020872, PMID:2226838, PMID:8159166] +comment: This reaction is the first step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG). +synonym: "2PGK activity" EXACT [GOC:bf] +xref: EC:2.7.2 +is_a: GO:0016301 ! kinase activity +relationship: part_of GO:1901369 ! cyclic 2,3-bisphospho-D-glycerate biosynthetic process +created_by: bf +creation_date: 2012-09-19T15:06:25Z + +[Term] +id: GO:0036358 +name: lipoteichoic acid D-alanylation +namespace: biological_process +def: "The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA)." [GOC:crds, PMID:22750871, PMID:8682792] +synonym: "D-alanyl lipoteichoic acid formation" EXACT [PMID:8682792] +synonym: "D-alanyl LTA formation" EXACT [PMID:8682792] +synonym: "LTA D-alanylation" EXACT [PMID:22750871] +is_a: GO:0070400 ! teichoic acid D-alanylation +created_by: bf +creation_date: 2012-09-19T15:09:05Z + +[Term] +id: GO:0036359 +name: renal potassium excretion +namespace: biological_process +def: "The elimination by an organism of potassium in the urine." [GOC:gap, PMID:15034090, PMID:16014448] +synonym: "renal K(+) excretion" EXACT [PMID:16014448] +synonym: "renal K+ elimination" EXACT [PMID:15034090] +synonym: "renal potassium ion excretion" EXACT [GOC:bf] +is_a: GO:0003014 ! renal system process +is_a: GO:0007588 ! excretion +created_by: bf +creation_date: 2012-09-20T11:10:47Z + +[Term] +id: GO:0036360 +name: sorocarp stalk morphogenesis +namespace: biological_process +def: "The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum." [DDANAT:0000068, GOC:pf, PMID:22902739] +synonym: "fruiting body stalk morphogenesis" BROAD [DDANAT:0000068] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0031150 ! sorocarp stalk development +relationship: part_of GO:0031288 ! sorocarp morphogenesis +created_by: bf +creation_date: 2012-09-20T11:21:30Z + +[Term] +id: GO:0036361 +name: racemase activity, acting on amino acids and derivatives +namespace: molecular_function +def: "Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative." [GOC:crds] +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives +created_by: bf +creation_date: 2012-09-21T11:13:47Z + +[Term] +id: GO:0036362 +name: ascus membrane +namespace: cellular_component +def: "A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi." [GOC:mcc, GOC:vw, PMID:21900489] +is_a: GO:0016020 ! membrane +created_by: bf +creation_date: 2012-09-21T11:21:41Z + +[Term] +id: GO:0036363 +name: transforming growth factor beta activation +namespace: biological_process +def: "The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms." [GOC:bf, GOC:sl, PMID:12482908, PMID:9170210] +synonym: "L-TGF-beta activation" EXACT [PMID:2070685] +synonym: "latent TGF-beta activation" EXACT [PMID:2070685] +synonym: "TGF-B activation" EXACT [GOC:sl] +synonym: "TGF-beta activation" EXACT [PR:000000046] +synonym: "TGFB activation" EXACT [GOC:sl] +synonym: "TGFbeta activation" EXACT [GOC:bf] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0071604 ! transforming growth factor beta production +created_by: bf +creation_date: 2012-09-24T10:06:56Z + +[Term] +id: GO:0036364 +name: transforming growth factor beta1 activation +namespace: biological_process +def: "The release of transforming growth factor beta1 (TGF-beta1) from its latent state." [GOC:sl, PMID:12482908, PMID:9170210] +synonym: "L-TGF-beta 1 activation" EXACT [PMID:2070685] +synonym: "latent-TGF-beta1 activation" EXACT [PMID:19439069] +synonym: "TGF-beta 1 activation" EXACT [PR:000000182] +synonym: "TGFB1 activation" EXACT [PR:000000182] +synonym: "TGFbeta 1 activation" EXACT [GOC:bf] +synonym: "transforming growth factor-beta1 activation" EXACT [PMID:19513812] +is_a: GO:0036363 ! transforming growth factor beta activation +relationship: part_of GO:0032905 ! transforming growth factor beta1 production +created_by: bf +creation_date: 2012-09-24T10:09:02Z + +[Term] +id: GO:0036365 +name: transforming growth factor beta2 activation +namespace: biological_process +def: "The release of transforming growth factor beta 2 (TGF-beta2) from its latent state." [GOC:sl, PMID:12482908, PMID:9170210] +synonym: "TGF-beta 2 activation" EXACT [PR:000000183] +synonym: "TGFB2 activation" EXACT [PR:000000183] +synonym: "TGFbeta 2 activation" EXACT [GOC:bf] +is_a: GO:0036363 ! transforming growth factor beta activation +relationship: part_of GO:0032906 ! transforming growth factor beta2 production +created_by: bf +creation_date: 2012-09-24T10:15:11Z + +[Term] +id: GO:0036366 +name: transforming growth factor beta3 activation +namespace: biological_process +def: "The release of transforming growth factor beta 3 (TGF-beta3) from its latent state." [GOC:sl, PMID:12482908, PMID:9170210] +synonym: "TGF-beta 3 activation" EXACT [PR:000000184] +synonym: "TGFB3 activation" EXACT [PR:000000184] +synonym: "TGFbeta 3 activation" EXACT [GOC:bf] +is_a: GO:0036363 ! transforming growth factor beta activation +relationship: part_of GO:0032907 ! transforming growth factor beta3 production +created_by: bf +creation_date: 2012-09-24T10:16:05Z + +[Term] +id: GO:0036367 +name: light adaption +namespace: biological_process +def: "The ability of a photoreceptor to adjust to varying levels of light." [GOC:gap, PMID:16039565] +comment: Light adaptation is usually a combination of cell desensitization and response acceleration. +is_a: GO:0009642 ! response to light intensity +created_by: bf +creation_date: 2012-09-26T13:28:14Z + +[Term] +id: GO:0036368 +name: cone photoresponse recovery +namespace: biological_process +def: "The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers." [GOC:gap, PMID:16039565, PMID:22802362] +synonym: "cone phototransduction termination" RELATED [GOC:bf] +synonym: "cone response recovery" EXACT [PMID:12732716] +is_a: GO:0009416 ! response to light stimulus +created_by: bf +creation_date: 2012-09-26T14:35:20Z + +[Term] +id: GO:0036369 +name: transcription factor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:al, GOC:vw, PMID:22833559] +synonym: "proteasome-mediated transcription factor catabolism" EXACT [GOC:bf] +synonym: "sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:bf] +synonym: "transcription factor breakdown" EXACT [GOC:bf] +synonym: "transcription factor catabolism" EXACT [GOC:bf] +synonym: "transcription factor degradation" EXACT [PMID:22833559] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +created_by: bf +creation_date: 2012-10-05T10:53:55Z + +[Term] +id: GO:0036370 +name: D-alanyl carrier activity +namespace: molecular_function +def: "Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG)." [GOC:crds, PMID:11222605, PMID:22750871, PMID:8682792] +synonym: "D-alanyl carrier protein" RELATED [GOC:crds, PMID:11222605] +is_a: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: part_of GO:0070400 ! teichoic acid D-alanylation +relationship: part_of GO:0070400 ! teichoic acid D-alanylation +created_by: bf +creation_date: 2012-10-08T10:30:33Z + +[Term] +id: GO:0036371 +name: protein localization to T-tubule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril." [GOC:BHF, GOC:rl, PMID:16292983] +synonym: "protein localisation to T-tubule" EXACT [GOC:rl] +synonym: "protein localization to T tubule" EXACT [GOC:rl] +synonym: "protein localization to transverse tubule" EXACT [GOC:rl] +is_a: GO:0072659 ! protein localization to plasma membrane +created_by: bf +creation_date: 2012-10-08T17:10:29Z + +[Term] +id: GO:0036372 +name: opsin transport +namespace: biological_process +def: "The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore." [GOC:atm, PMID:20238016, PMID:22855808] +synonym: "ciliary transport of opsin" NARROW [GOC:20238016] +is_a: GO:0015031 ! protein transport +created_by: bf +creation_date: 2013-04-23T09:26:29Z + +[Term] +id: GO:0036373 +name: L-fucose mutarotase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-L-fucose = beta-L-fucose." [GOC:crds, PMID:15060078, RHEA:25580] +synonym: "alpha-L-fucose 1-epimerase activity" EXACT [EC:5.1.3.29] +synonym: "fucose 1-epimerase activity" EXACT [EC:5.1.3.29] +synonym: "type-2 mutarotase activity" EXACT [EC:5.1.3.29] +xref: EC:5.1.3.29 +xref: MetaCyc:RXN0-5298 +xref: RHEA:25580 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives +created_by: bf +creation_date: 2013-05-07T09:51:06Z + +[Term] +id: GO:0036374 +name: glutathione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate." [EC:3.4.19.13, GOC:imk] +synonym: "gamma-glutamyltranspeptidase activity" EXACT [EC:3.4.19.13] +synonym: "glutathionase activity" EXACT [EC:3.4.19.13] +xref: EC:3.4.19.13 +xref: KEGG_REACTION:R00494 +xref: MetaCyc:RXN-12618 +xref: Reactome:R-HSA-1222712 "Nitrosoglutathione gets cleaved to Cys(NO)-Gly" +xref: Reactome:R-HSA-266046 "GGT1, 5 dimers hydrolyse LTC4 to LTD4" +xref: Reactome:R-HSA-5433072 "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG" +xref: Reactome:R-HSA-5602984 "Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG" +xref: Reactome:R-HSA-8943279 "GGT dimers hydrolyse GSH" +xref: Reactome:R-HSA-9026757 "GGT hydrolyses MCTR1 to MCTR2" +xref: Reactome:R-HSA-9026907 "GGT hydrolyses PCTR2 to PCTR3" +xref: Reactome:R-HSA-9026912 "GGT hydrolyses PCTR1 to PCTR2" +xref: Reactome:R-HSA-9026916 "GGT hydrolyses RCTR2 to RCTR3" +xref: Reactome:R-HSA-9026927 "GGT hydrolyses RCTR1 to RCTR2" +xref: Reactome:R-HSA-9035966 "Defective GGT1 does not hydrolyse GSH" +xref: RHEA:28807 +is_a: GO:0008242 ! omega peptidase activity +created_by: bf +creation_date: 2013-05-07T09:58:07Z + +[Term] +id: GO:0036375 +name: Kibra-Ex-Mer complex +namespace: cellular_component +def: "An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2." [PMID:20159598] +synonym: "Kbr, Ex and Mer complex" EXACT [PMID:20159598] +synonym: "KEM complex" EXACT [PMID:20159598] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0045177 ! apical part of cell +created_by: bf +creation_date: 2013-05-07T10:05:15Z + +[Term] +id: GO:0036376 +name: sodium ion export across plasma membrane +namespace: biological_process +alt_id: GO:0071436 +alt_id: GO:0098667 +def: "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:vw, PMID:14674689] +synonym: "sodium export" RELATED [GOC:mah] +synonym: "sodium ion export" RELATED [] +synonym: "sodium ion export from cell" EXACT [] +is_a: GO:0035725 ! sodium ion transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +created_by: mah +creation_date: 2009-12-16T11:13:55Z + +[Term] +id: GO:0036377 +name: arbuscular mycorrhizal association +namespace: biological_process +def: "A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil." [GOC:sk, Wikipedia:Arbuscular_mycorrhiza] +synonym: "arbuscular mycorrhizae formation" EXACT [Wikipedia:Arbuscular_mycorrhiza] +synonym: "arbuscular mycorrhizal symbiosis" RELATED [Wikipedia:Arbuscular_mycorrhiza] +synonym: "arbuscular mycorrhizas formation" EXACT [Wikipedia:Arbuscular_mycorrhiza] +is_a: GO:0044403 ! symbiotic process +created_by: bf +creation_date: 2013-05-07T15:07:32Z + +[Term] +id: GO:0036378 +name: calcitriol biosynthetic process from calciol +namespace: biological_process +def: "Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol." [GOC:BHF, GOC:rl, PMID:17426122, PMID:20511049] +synonym: "1alpha,25(OH)2D3 biosynthesis" BROAD [CHEBI:17823] +synonym: "1alpha,25-dihydroxycholecalciferol biosynthesis" BROAD [CHEBI:17823] +synonym: "1alpha,25-dihydroxyvitamin D3 biosynthesis" BROAD [CHEBI:17823] +synonym: "calcitriol biosynthesis from calciol" EXACT [GOC:bf] +synonym: "vitamin D3 activation" EXACT [GOC:bf, PMID:20506379] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042368 ! vitamin D biosynthetic process +is_a: GO:0044108 ! cellular alcohol biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0070640 ! vitamin D3 metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process +created_by: bf +creation_date: 2013-05-15T11:46:08Z + +[Term] +id: GO:0036379 +name: myofilament +namespace: cellular_component +def: "Any of the smallest contractile units of a myofibril (striated muscle fiber)." [Wikipedia:Myofilament] +synonym: "striated muscle filament" EXACT [GOC:bf] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030016 ! myofibril +created_by: bf +creation_date: 2013-05-22T14:39:06Z + +[Term] +id: GO:0036380 +name: UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol." [EC:2.7.8.33, GOC:rs] +synonym: "GlcNAc-P-P-Und synthase activity" EXACT [EC:2.7.8.33] +synonym: "UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity" EXACT [EC:2.7.8.33] +synonym: "UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity" EXACT [EC:2.7.8.33] +synonym: "UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity" EXACT [EC:2.7.8.33] +synonym: "UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity" EXACT [EC:2.7.8.33] +xref: EC:2.7.8.33 +xref: KEGG_REACTION:R08856 +xref: MetaCyc:GLCNACPTRANS-RXN +xref: RHEA:28090 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: bf +creation_date: 2013-05-23T10:51:26Z + +[Term] +id: GO:0036381 +name: pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate." [EC:4.3.3.6, GOC:rs] +synonym: "PdxST activity" EXACT [EC:4.3.3.6] +synonym: "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity" EXACT [EC:4.3.3.6] +xref: EC:4.3.3.6 +xref: KEGG_REACTION:R10089 +xref: MetaCyc:RXN-11322 +xref: RHEA:31507 +is_a: GO:0016843 ! amine-lyase activity +created_by: bf +creation_date: 2013-05-23T11:15:37Z + +[Term] +id: GO:0036382 +name: flavin reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+." [EC:1.5.1.36, GOC:rs] +synonym: "flavin:NADH oxidoreductase activity" EXACT [EC:1.5.1.36] +synonym: "NADH-dependent flavin reductase activity" EXACT [EC:1.5.1.36] +xref: EC:1.5.1.36 +xref: KEGG_REACTION:R09662 +xref: MetaCyc:1.5.1.36-RXN +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2013-05-23T11:23:09Z + +[Term] +id: GO:0036383 +name: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O." [EC:1.14.14.12, GOC:rs] +xref: EC:1.14.14.12 +xref: KEGG_REACTION:R09819 +xref: MetaCyc:1.14.14.12-RXN +xref: RHEA:31731 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen +created_by: bf +creation_date: 2013-05-23T11:31:09Z + +[Term] +id: GO:0036384 +name: cytidine diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP + H2O = CMP + phosphate." [GOC:al] +synonym: "CDPase activity" EXACT [GOC:al] +is_a: GO:0017110 ! nucleoside-diphosphatase activity +created_by: bf +creation_date: 2013-05-23T13:33:01Z + +[Term] +id: GO:0036385 +name: nucleoid DNA packaging +namespace: biological_process +def: "Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid." [GOC:bf, GOC:bhm] +is_a: GO:0006323 ! DNA packaging +intersection_of: GO:0006323 ! DNA packaging +intersection_of: occurs_in GO:0009295 ! nucleoid +relationship: occurs_in GO:0009295 ! nucleoid +created_by: bf +creation_date: 2013-05-30T10:36:05Z + +[Term] +id: GO:0036386 +name: bacterial nucleoid DNA packaging +namespace: biological_process +def: "Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling." [GOC:bf, GOC:bhm, PMID:17097674, PMID:17360520] +synonym: "chromosomal compaction" BROAD [PMID:17097674] +synonym: "nucleoid compaction" BROAD [PMID:17097674] +synonym: "prokaryotic DNA condensation" BROAD [Wikipedia:DNA_condensation] +is_a: GO:0036385 ! nucleoid DNA packaging +intersection_of: GO:0006323 ! DNA packaging +intersection_of: occurs_in GO:0043590 ! bacterial nucleoid +relationship: occurs_in GO:0043590 ! bacterial nucleoid +created_by: bf +creation_date: 2013-05-30T10:41:08Z + +[Term] +id: GO:0036387 +name: pre-replicative complex +namespace: cellular_component +def: "A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication." [GOC:bf, GOC:bhm, GOC:jh2, Wikipedia:Pre-replication_complex] +comment: This term describes pre-replicative complexes across organisms. +synonym: "pre-RC" EXACT [Wikipedia:Pre-replication_complex] +synonym: "pre-replication complex" EXACT [Wikipedia:Pre-replication_complex] +is_a: GO:0032993 ! protein-DNA complex +created_by: bf +creation_date: 2013-06-05T16:14:52Z + +[Term] +id: GO:0036388 +name: pre-replicative complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication." [GOC:bf, GOC:bhm, GOC:jh2] +synonym: "pre-RC assembly" EXACT [Wikipedia:Pre-replication_complex] +synonym: "pre-replication complex assembly" RELATED [Wikipedia:Pre-replication_complex] +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0006261 ! DNA-dependent DNA replication +created_by: bf +creation_date: 2013-06-05T16:29:13Z + +[Term] +id: GO:0036389 +name: bacterial pre-replicative complex +namespace: cellular_component +def: "A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication." [GOC:bf, GOC:bhm, GOC:jh2, PMID:19833870, PMID:21035377, Wikipedia:Pre-replication_complex] +synonym: "bacterial pre-RC" EXACT [GOC:bf, GOC:bhm, GOC:jh2] +is_a: GO:0036387 ! pre-replicative complex +relationship: has_part GO:1990101 ! DnaA-oriC complex +created_by: bf +creation_date: 2013-06-05T16:41:47Z + +[Term] +id: GO:0036390 +name: pre-replicative complex assembly involved in bacterial-type DNA replication +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication." [GOC:bf, GOC:bhm, GOC:jh2, PMID:19833870, PMID:21035377, PMID:21895796] +synonym: "bacterial pre-RC assembly" EXACT [GOC:bf, GOC:bhm, GOC:jh2] +synonym: "bacterial pre-replicative complex assembly" EXACT [] +is_a: GO:1902299 ! pre-replicative complex assembly involved in cell cycle DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: bf +creation_date: 2013-06-05T16:45:21Z + +[Term] +id: GO:0036391 +name: medial cortex septin ring +namespace: cellular_component +def: "A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins." [GOC:vw, PMID:16009555] +is_a: GO:0005940 ! septin ring +is_a: GO:0032161 ! cleavage apparatus septin structure +intersection_of: GO:0005940 ! septin ring +intersection_of: part_of GO:0031097 ! medial cortex +relationship: part_of GO:0031097 ! medial cortex +created_by: bf +creation_date: 2013-06-06T16:12:06Z + +[Term] +id: GO:0036392 +name: chemokine (C-C motif) ligand 20 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:jc] +synonym: "C-C motif chemokine 20 production" EXACT [] +synonym: "CCL-20 production" EXACT [] +synonym: "CCL20 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: bf +creation_date: 2013-06-17T14:42:07Z + +[Term] +id: GO:0036393 +name: thiocyanate peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate." [GOC:pm, PMID:12626341] +synonym: "lactoperoxidase activity" BROAD [PMID:12626341, Wikipedia:Lactoperoxidase] +is_a: GO:0004601 ! peroxidase activity +relationship: part_of GO:0018969 ! thiocyanate metabolic process +created_by: bf +creation_date: 2013-06-20T16:03:57Z + +[Term] +id: GO:0036394 +name: amylase secretion +namespace: biological_process +def: "The controlled release of amylase from a cell." [GOC:jc, PMID:19028687] +synonym: "amylase release" EXACT [PMID:19028687] +is_a: GO:0009306 ! protein secretion +created_by: bf +creation_date: 2013-07-01T13:03:19Z + +[Term] +id: GO:0036395 +name: pancreatic amylase secretion +namespace: biological_process +def: "The controlled release of amylase from a cell of the pancreas." [GOC:jc, PMID:19028687] +is_a: GO:0036394 ! amylase secretion +relationship: part_of GO:0030157 ! pancreatic juice secretion +created_by: bf +creation_date: 2013-07-01T13:42:34Z + +[Term] +id: GO:0036396 +name: RNA N6-methyladenosine methyltransferase complex +namespace: cellular_component +def: "A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B)." [GOC:dgf, GOC:sp, PMID:22685417, PMID:24316715, PMID:24407421, PMID:29507755, PMID:29535189, PMID:29547716] +synonym: "m(6)A writer complex" RELATED [] +synonym: "m6A methyltransferase complex" RELATED [] +synonym: "METTL3-METTL14-WTAP methyltransferase complex" RELATED [] +synonym: "MIS complex" RELATED [] +synonym: "Mum2, Ime4, and Slz1 complex" EXACT [PMID:22685417] +synonym: "WMM complex" EXACT [] +is_a: GO:0034708 ! methyltransferase complex +is_a: GO:0045293 ! mRNA editing complex +created_by: bf +creation_date: 2013-07-15T10:17:50Z + +[Term] +id: GO:0036397 +name: formate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: formate + a quinone = CO2 + a quinol." [EC:1.1.5.6, GOC:bhm] +synonym: "Fdh-N activity" RELATED [EC:1.1.5.6] +synonym: "formate dehydrogenase-N activity" RELATED [EC:1.1.5.6] +synonym: "formate:quinone oxidoreductase activity" EXACT [EC:1.1.5.6] +xref: EC:1.1.5.6 +xref: KEGG_REACTION:R09494 +xref: MetaCyc:FORMATEDEHYDROG-RXN +is_a: GO:0052738 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor +created_by: bf +creation_date: 2013-07-18T13:11:41Z + +[Term] +id: GO:0036398 +name: TCR signalosome +namespace: cellular_component +def: "A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology." [GOC:krc, PMID:17534068, PMID:20107804, PMID:22426112] +synonym: "LAT signalosome" EXACT [GOC:krc, PMID:17534068] +synonym: "linker for activation of T cells signalosome" EXACT [PMID:17534068] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0042101 ! T cell receptor complex +created_by: bf +creation_date: 2013-07-18T13:52:24Z + +[Term] +id: GO:0036399 +name: TCR signalosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome." [GOC:krc, PMID:22426112] +synonym: "LAT signalosome assembly" EXACT [GOC:krc, PMID:17534068] +synonym: "linker for activation of T cells signalosome assembly" EXACT [PMID:17534068] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2013-07-18T14:02:53Z + +[Term] +id: GO:0036400 +name: short neuropeptide F receptor activity +namespace: molecular_function +def: "Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide." [GOC:ha, PMID:16330127, PMID:21440021] +comment: Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related. +synonym: "sNPF receptor activity" EXACT [PMID:12372405, PMID:21440021] +is_a: GO:0008188 ! neuropeptide receptor activity +created_by: bf +creation_date: 2013-07-18T14:46:40Z + +[Term] +id: GO:0036401 +name: pyrokinin receptor activity +namespace: molecular_function +def: "Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation." [GOC:ha, PMID:12951076, PMID:19186060] +synonym: "PK receptor activity" EXACT [PMID:17065249] +is_a: GO:0008188 ! neuropeptide receptor activity +created_by: bf +creation_date: 2013-07-18T15:10:55Z + +[Term] +id: GO:0036402 +name: proteasome-activating ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome." [GOC:rb, PMID:11430818] +synonym: "ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:bf] +synonym: "proteasomal ATPase activity" EXACT [GOC:bf] +synonym: "proteasome channel gating activity" NARROW [GOC:rb] +synonym: "proteasome channel opening activity" NARROW [GOC:rb] +is_a: GO:0016887 ! ATPase activity +intersection_of: GO:0016887 ! ATPase activity +intersection_of: part_of GO:1901800 ! positive regulation of proteasomal protein catabolic process +relationship: part_of GO:1901800 ! positive regulation of proteasomal protein catabolic process +created_by: bf +creation_date: 2013-08-12T11:38:20Z + +[Term] +id: GO:0036403 +name: arachidonate 8(S)-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate." [EC:1.13.11.-, GOC:lb, PMID:10625675] +comment: This activity produces the S-enantiomer of HPETE, 8(S)-HPETE. For the reaction producing the S-enantiomer, see GO:0047677. +synonym: "8(S)-lipoxygenase activity" BROAD [GOC:bf] +synonym: "8-lipoxygenase (S-type)" BROAD [KEGG_REACTION:R07053] +xref: EC:1.13.11 +xref: KEGG_REACTION:R07053 +xref: RHEA:38675 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +created_by: bf +creation_date: 2013-08-14T11:48:46Z + +[Term] +id: GO:0036404 +name: conversion of ds siRNA to ss siRNA +namespace: biological_process +def: "The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA)." [GOC:vw] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA" RELATED [GOC:bf] +is_a: GO:0006396 ! RNA processing +relationship: part_of GO:0031050 ! dsRNA processing +created_by: bf +creation_date: 2013-08-14T14:24:19Z + +[Term] +id: GO:0036405 +name: anchored component of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:md] +synonym: "anchored to cell outer membrane" NARROW [] +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0031230 ! intrinsic component of cell outer membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0009279 ! cell outer membrane +created_by: bf +creation_date: 2013-08-15T11:40:41Z + +[Term] +id: GO:0036406 +name: anchored component of periplasmic side of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only." [GOC:dos, GOC:md] +synonym: "anchored to internal side of cell outer membrane" EXACT [] +synonym: "anchored to periplasmic side of cell outer membrane" NARROW [] +is_a: GO:0031246 ! intrinsic component of periplasmic side of cell outer membrane +is_a: GO:0036405 ! anchored component of cell outer membrane +intersection_of: GO:0036405 ! anchored component of cell outer membrane +intersection_of: part_of GO:0031241 ! periplasmic side of cell outer membrane +created_by: bf +creation_date: 2013-08-15T11:45:39Z + +[Term] +id: GO:0036407 +name: mycolate outer membrane +namespace: cellular_component +def: "A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria)." [GOC:bf, GOC:das, GOC:md, PMID:18316738, PMID:18567661] +synonym: "MOM" EXACT [GOC:md] +synonym: "mycobacterial outer membrane" EXACT [GOC:md] +synonym: "mycolate outer membrane" NARROW [GOC:md] +synonym: "mycomembrane" EXACT [GOC:das, GOC:md] +is_a: GO:0009279 ! cell outer membrane +created_by: bf +creation_date: 2013-08-15T13:33:46Z + +[Term] +id: GO:0036408 +name: histone acetyltransferase activity (H3-K14 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14)." [GOC:vw, PMID:21289066] +synonym: "histone lysine N-acetyltransferase activity (H3-K14 specific)" EXACT [GOC:bf] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0044154 ! histone H3-K14 acetylation +created_by: bf +creation_date: 2013-08-21T10:03:10Z + +[Term] +id: GO:0036409 +name: histone H3-K14 acetyltransferase complex +namespace: cellular_component +def: "A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3." [GOC:vw, PMID:21289066] +synonym: "H3-K14 histone acetyltransferase complex" EXACT [GOC:bf] +synonym: "histone acetyltransferase complex (H3-K14 specific)" EXACT [GOC:bf] +synonym: "histone H3 Lys 14 (H3K14) acetyltransferase complex" EXACT [PMID:21289066] +synonym: "histone H3K14 acetyltransferase complex" EXACT [PMID:21289066] +is_a: GO:0070775 ! H3 histone acetyltransferase complex +created_by: bf +creation_date: 2013-08-21T10:06:34Z + +[Term] +id: GO:0036410 +name: Mst2 histone acetyltransferase complex +namespace: cellular_component +def: "A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6." [GOC:vw, PMID:21289066] +synonym: "Mst2 complex" EXACT [PMID:21289066] +synonym: "Mst2 H3K14 acetyltransferase complex" EXACT [PMID:21289066] +synonym: "Mst2 histone H3K14 acetyltransferase complex" EXACT [PMID:21289066] +is_a: GO:0036409 ! histone H3-K14 acetyltransferase complex +created_by: bf +creation_date: 2013-08-21T10:11:32Z + +[Term] +id: GO:0036411 +name: H-NS-Cnu complex +namespace: cellular_component +def: "A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes." [GOC:bhm, PMID:18189420, PMID:22358512] +is_a: GO:0017053 ! transcription repressor complex +relationship: has_part GO:1990121 ! H-NS complex +created_by: bf +creation_date: 2013-08-22T10:19:24Z + +[Term] +id: GO:0036412 +name: acetyl-CoA:oxalate CoA-transferase +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA." [GOC:imk, PMID:23935849] +xref: RHEA:37883 +is_a: GO:0008410 ! CoA-transferase activity +created_by: bf +creation_date: 2013-08-22T13:43:25Z + +[Term] +id: GO:0036413 +name: histone H3-R26 citrullination +namespace: biological_process +def: "The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3." [GOC:als, PMID:22853951] +synonym: "histone H3 arginine 26 citrullination" EXACT [GOC:als] +is_a: GO:0036414 ! histone citrullination +created_by: bf +creation_date: 2013-08-22T13:59:15Z + +[Term] +id: GO:0036414 +name: histone citrullination +namespace: biological_process +def: "The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein." [GOC:als, PMID:22853951, PMID:23175390] +synonym: "histone deimination" EXACT [Wikipedia:Citrullination] +is_a: GO:0016570 ! histone modification +is_a: GO:0018101 ! protein citrullination +created_by: bf +creation_date: 2013-08-22T14:04:26Z + +[Term] +id: GO:0036415 +name: regulation of tRNA stability +namespace: biological_process +def: "Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs." [GOC:aa, PMID:21502523, PMID:23572593] +is_a: GO:0043487 ! regulation of RNA stability +is_a: GO:1902370 ! regulation of tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:22:13Z + +[Term] +id: GO:0036416 +name: tRNA stabilization +namespace: biological_process +def: "Prevention of degradation of tRNA molecules." [GOC:aa, GOC:bf, PMID:20459084] +is_a: GO:0036415 ! regulation of tRNA stability +is_a: GO:0043489 ! RNA stabilization +is_a: GO:1902371 ! negative regulation of tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:41:26Z + +[Term] +id: GO:0036417 +name: tRNA destabilization +namespace: biological_process +def: "Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes." [GOC:aa, GOC:bf] +is_a: GO:0036415 ! regulation of tRNA stability +is_a: GO:0050779 ! RNA destabilization +is_a: GO:1902372 ! positive regulation of tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:43:13Z + +[Term] +id: GO:0036418 +name: intrinsic component of mycolate outer membrane +namespace: cellular_component +def: "The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:md] +synonym: "intrinsic to MOM" EXACT [GOC:md] +synonym: "intrinsic to mycolate outer membrane" NARROW [] +synonym: "intrinsic to mycomembrane" EXACT [GOC:das, GOC:md] +is_a: GO:0031230 ! intrinsic component of cell outer membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0036407 ! mycolate outer membrane +relationship: part_of GO:0036407 ! mycolate outer membrane +created_by: bf +creation_date: 2013-09-05T20:19:04Z + +[Term] +id: GO:0036419 +name: integral component of mycolate outer membrane +namespace: cellular_component +def: "The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:md] +synonym: "integral to MOM" EXACT [GOC:md] +synonym: "integral to mycolate outer membrane" NARROW [] +synonym: "integral to mycomembrane" EXACT [GOC:das, GOC:md] +is_a: GO:0036418 ! intrinsic component of mycolate outer membrane +is_a: GO:0045203 ! integral component of cell outer membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0036407 ! mycolate outer membrane +created_by: bf +creation_date: 2013-09-05T20:20:04Z + +[Term] +id: GO:0036420 +name: extrinsic component of mycolate outer membrane +namespace: cellular_component +def: "The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, GOC:md] +synonym: "extrinsic to MOM" EXACT [GOC:md] +synonym: "extrinsic to mycolate outer membrane" NARROW [] +synonym: "extrinsic to mycomembrane" EXACT [GOC:das, GOC:md] +is_a: GO:0031244 ! extrinsic component of cell outer membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0036407 ! mycolate outer membrane +relationship: part_of GO:0036407 ! mycolate outer membrane +created_by: bf +creation_date: 2013-09-05T20:22:02Z + +[Term] +id: GO:0036421 +name: extrinsic component of external side of mycolate outer membrane +namespace: cellular_component +def: "The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region." [GOC:md] +synonym: "extrinsic to external side of MOM" EXACT [GOC:md] +synonym: "extrinsic to external side of mycolate outer membrane" NARROW [] +synonym: "extrinsic to external side of mycomembrane" EXACT [GOC:das, GOC:md] +is_a: GO:0031242 ! extrinsic component of external side of cell outer membrane +is_a: GO:0036420 ! extrinsic component of mycolate outer membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098568 ! external side of mycolate outer membrane +relationship: part_of GO:0098568 ! external side of mycolate outer membrane +created_by: bf +creation_date: 2013-09-05T20:23:45Z + +[Term] +id: GO:0036422 +name: heptaprenyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate." [EC:2.5.1.30, RHEA:27794] +synonym: "all-trans-heptaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.30] +synonym: "HepPP synthase activity" EXACT [EC:2.5.1.30] +synonym: "heptaprenyl pyrophosphate synthase activity" EXACT [EC:2.5.1.30] +synonym: "heptaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.30] +xref: EC:2.5.1.30 +xref: MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN +xref: RHEA:27794 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: bf +creation_date: 2013-09-16T11:50:41Z + +[Term] +id: GO:0036423 +name: hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate." [EC:2.5.1.83, RHEA:27559] +synonym: "hexaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.83] +synonym: "hexaprenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.83] +xref: EC:2.5.1.83 +xref: KEGG_REACTION:R09245 +xref: MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN +xref: RHEA:27559 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: bf +creation_date: 2013-09-16T12:22:10Z + +[Term] +id: GO:0036424 +name: L-phosphoserine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-serine + H2O <=> L-serine + phosphate." [RHEA:21208] +xref: KEGG_REACTION:R00582 +xref: MetaCyc:RXN0-5114 +xref: RHEA:21208 +is_a: GO:0004647 ! phosphoserine phosphatase activity +created_by: bf +creation_date: 2013-09-16T13:01:03Z + +[Term] +id: GO:0036425 +name: D-phosphoserine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-D-serine + H2O <=> L-serine + phosphate." [RHEA:24873] +xref: KEGG_REACTION:R02853 +xref: RHEA:24873 +is_a: GO:0004647 ! phosphoserine phosphatase activity +created_by: bf +creation_date: 2013-09-16T13:02:43Z + +[Term] +id: GO:0036426 +name: ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP." [RHEA:28118] +xref: KEGG_REACTION:R07257 +xref: MetaCyc:2.4.1.54-RXN +xref: RHEA:28118 +is_a: GO:0047267 ! undecaprenyl-phosphate mannosyltransferase activity +created_by: bf +creation_date: 2013-09-16T13:21:01Z + +[Term] +id: GO:0036427 +name: all-trans-undecaprenyl-phosphate mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP." [RHEA:12784] +xref: RHEA:12784 +is_a: GO:0047267 ! undecaprenyl-phosphate mannosyltransferase activity +created_by: bf +creation_date: 2013-09-16T13:23:06Z + +[Term] +id: GO:0036428 +name: adenosylcobinamide kinase (GTP-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+." [RHEA:15765] +xref: KEGG_REACTION:R06558 +xref: MetaCyc:RXN-14063 +xref: RHEA:15765 +is_a: GO:0043752 ! adenosylcobinamide kinase activity +created_by: bf +creation_date: 2013-09-16T14:05:39Z + +[Term] +id: GO:0036429 +name: adenosylcobinamide kinase (ATP-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+." [RHEA:15769] +xref: KEGG_REACTION:R05221 +xref: MetaCyc:COBINAMIDEKIN-RXN +xref: RHEA:15769 +is_a: GO:0043752 ! adenosylcobinamide kinase activity +created_by: bf +creation_date: 2013-09-16T14:05:56Z + +[Term] +id: GO:0036430 +name: CMP kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CMP = ADP + CDP." [RHEA:11600] +xref: KEGG_REACTION:R00512 +xref: MetaCyc:RXN-11832 +xref: RHEA:11600 +is_a: GO:0004127 ! cytidylate kinase activity +created_by: bf +creation_date: 2013-09-16T14:11:48Z + +[Term] +id: GO:0036431 +name: dCMP kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dCMP = ADP + dCDP." [RHEA:25094] +synonym: "ATP:dCMP phosphotransferase activity" EXACT [KEGG_REACTION:R01665] +xref: KEGG_REACTION:R01665 +xref: MetaCyc:RXN-11831 +xref: MetaCyc:RXN-7913 +xref: RHEA:25094 +is_a: GO:0004127 ! cytidylate kinase activity +created_by: bf +creation_date: 2013-09-16T14:11:56Z + +[Term] +id: GO:0036432 +name: all-trans undecaprenol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+." [RHEA:23752] +xref: RHEA:23752 +is_a: GO:0009038 ! undecaprenol kinase activity +created_by: bf +creation_date: 2013-09-16T14:21:04Z + +[Term] +id: GO:0036433 +name: di-trans, poly-cis-undecaprenol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+." [RHEA:28122] +synonym: "ditrans,polycis-undecaprenol kinase activity" RELATED [] +xref: KEGG_REACTION:R05626 +xref: MetaCyc:UNDECAPRENOL-KINASE-RXN +xref: RHEA:28122 +is_a: GO:0009038 ! undecaprenol kinase activity +created_by: bf +creation_date: 2013-09-16T14:21:12Z + +[Term] +id: GO:0036434 +name: nitronate monooxygenase (FMN-linked) activity +namespace: molecular_function +def: "Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite." [RHEA:26458] +xref: KEGG_REACTION:R00025 +xref: RHEA:26458 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +created_by: bf +creation_date: 2013-09-16T16:20:13Z + +[Term] +id: GO:0036435 +name: K48-linked polyubiquitin modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein." [GOC:al, PMID:20739285] +xref: Reactome:R-HSA-5683077 "RNF8 and RNF168 ubiquitinate KDM4A,B" +is_a: GO:0031593 ! polyubiquitin modification-dependent protein binding +created_by: bf +creation_date: 2013-09-18T14:51:06Z + +[Term] +id: GO:0036436 +name: Isw1a complex +namespace: cellular_component +def: "An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p." [GOC:jd, PMID:12482963] +is_a: GO:0016587 ! Isw1 complex +created_by: bf +creation_date: 2013-09-18T16:45:41Z + +[Term] +id: GO:0036437 +name: Isw1b complex +namespace: cellular_component +def: "An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p." [GOC:jd, PMID:12482963] +is_a: GO:0016587 ! Isw1 complex +created_by: bf +creation_date: 2013-09-18T16:53:07Z + +[Term] +id: GO:0036438 +name: maintenance of lens transparency +namespace: biological_process +def: "A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina." [GOC:nhn, PMID:22095752] +synonym: "maintenance of ocular lens transparency" EXACT [PMID:22095752] +synonym: "preservation of lens transparency" EXACT [PMID:22095752] +is_a: GO:0001894 ! tissue homeostasis +created_by: bf +creation_date: 2013-09-23T13:51:09Z + +[Term] +id: GO:0036440 +name: citrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA." [RHEA:16845] +xref: KEGG_REACTION:R00351 +xref: RHEA:16845 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer +created_by: bf +creation_date: 2013-09-30T16:21:50Z + +[Term] +id: GO:0036441 +name: 2-dehydropantolactone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+." [RHEA:18981] +xref: KEGG_REACTION:R03155 +xref: RHEA:18981 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2013-09-30T16:26:27Z + +[Term] +id: GO:0036443 +name: dermatan 6-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate." [EC:2.8.2.33, GOC:bf, KEGG_REACTION:R07288] +xref: KEGG_REACTION:R07288 +is_a: GO:0008146 ! sulfotransferase activity +created_by: bf +creation_date: 2013-10-17T10:41:48Z + +[Term] +id: GO:0036444 +name: calcium import into the mitochondrion +namespace: biological_process +def: "A process in which a calcium ion (Ca2+) is transported from the cytosol, into the mitochondrial matrix." [GOC:vw] +synonym: "calcium ion import into mitochondrion" BROAD [] +synonym: "calcium ion transmembrane import into mitochondrion" EXACT [] +synonym: "mitochondrial calcium ion import" BROAD [GOC:vw] +synonym: "mitochondrial calcium uptake" EXACT [] +is_a: GO:0006851 ! mitochondrial calcium ion transmembrane transport +is_a: GO:0060401 ! cytosolic calcium ion transport +is_a: GO:0070509 ! calcium ion import +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: bf +creation_date: 2013-10-28T09:32:39Z + +[Term] +id: GO:0036445 +name: neuronal stem cell division +namespace: biological_process +def: "The self-renewing division of a neuronal stem cell." [CL:0000047, GOC:nhn] +synonym: "NSC division" EXACT [CL:0000047] +is_a: GO:0048103 ! somatic stem cell division +created_by: bf +creation_date: 2013-10-30T10:03:27Z + +[Term] +id: GO:0036446 +name: myofibroblast differentiation +namespace: biological_process +def: "The process in which an undifferentiated cell acquires the features of a myofibroblast cell." [CL:0000186, GOC:nhn] +synonym: "myofibroblast cell differentiation" EXACT [CL:0000186] +is_a: GO:0030154 ! cell differentiation +created_by: bf +creation_date: 2013-10-30T10:06:51Z + +[Term] +id: GO:0036447 +name: cellular response to sugar-phosphate stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate." [GOC:am, PMID:17383224] +synonym: "cellular response to presence of non-metabolizable sugars" RELATED [GOC:am] +is_a: GO:0062197 ! cellular response to chemical stress +created_by: bf +creation_date: 2013-10-31T11:18:09Z + +[Term] +id: GO:0036448 +name: cellular response to glucose-phosphate stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate." [GOC:am, PMID:17383224] +is_a: GO:0036447 ! cellular response to sugar-phosphate stress +created_by: bf +creation_date: 2013-10-31T11:20:08Z + +[Term] +id: GO:0036449 +name: microtubule minus-end +namespace: cellular_component +def: "The end of a microtubule that does not preferentially grow (polymerize)." [GOC:lb, PMID:23169647] +synonym: "microtubule minus end" EXACT [GOC:lb] +is_a: GO:1990752 ! microtubule end +created_by: bf +creation_date: 2013-10-31T13:26:51Z + +[Term] +id: GO:0036450 +name: polyuridylation-dependent decapping of nuclear-transcribed mRNA +namespace: biological_process +def: "Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end." [GOC:vw, PMID:19430462] +synonym: "uridylation-dependent decapping of nuclear-transcribed mRNA" BROAD [GOC:vw] +is_a: GO:0031087 ! deadenylation-independent decapping of nuclear-transcribed mRNA +relationship: part_of GO:1990074 ! polyuridylation-dependent mRNA catabolic process +created_by: bf +creation_date: 2013-11-04T11:37:28Z + +[Term] +id: GO:0036451 +name: cap mRNA methylation +namespace: biological_process +def: "Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA." [GOC:bf, PMID:20713356] +is_a: GO:0080009 ! mRNA methylation +created_by: bf +creation_date: 2013-11-06T14:36:00Z + +[Term] +id: GO:0036452 +name: ESCRT complex +namespace: cellular_component +def: "An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes." [PMID:16689637, VZ:1536] +synonym: "endosomal sorting complex required for transport" EXACT [PMID:22718754] +xref: Wikipedia:ESCRT +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005768 ! endosome +created_by: bf +creation_date: 2013-11-06T16:25:52Z + +[Term] +id: GO:0036453 +name: transitive RNA interference +namespace: biological_process +def: "An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence." [GOC:pf, PMID:11719187, PMID:12554873, PMID:23724097, PMID:24369430] +synonym: "transitive RNAi" EXACT [PMID:12554873] +is_a: GO:0016246 ! RNA interference +created_by: bf +creation_date: 2013-11-07T11:14:03Z + +[Term] +id: GO:0036454 +name: growth factor complex +namespace: cellular_component +def: "A protein complex that has growth factor activity." [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2013-11-07T11:27:16Z + +[Term] +id: GO:0036455 +name: iron-sulfur transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor)." [GOC:bhm] +synonym: "Fe-S transferase activity" EXACT [GOC:bf] +xref: Reactome:R-HSA-2564828 "CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins" +is_a: GO:0016782 ! transferase activity, transferring sulfur-containing groups +created_by: bf +creation_date: 2013-11-14T11:17:37Z + +[Term] +id: GO:0036456 +name: L-methionine-(S)-S-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O." [GOC:vw, RHEA:19995] +xref: RHEA:19995 +is_a: GO:0033744 ! L-methionine:thioredoxin-disulfide S-oxidoreductase activity +created_by: bf +creation_date: 2013-11-27T11:07:19Z + +[Term] +id: GO:0036457 +name: keratohyalin granule +namespace: cellular_component +def: "A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope." [GOC:krc, PMID:15854042] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2013-12-09T13:04:09Z + +[Term] +id: GO:0036458 +name: hepatocyte growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a hepatocyte growth factor." [PR:000008534] +synonym: "HGF binding" EXACT [PR:000008534] +is_a: GO:0019838 ! growth factor binding +created_by: bf +creation_date: 2013-12-09T14:07:20Z + +[Term] +id: GO:0036459 +name: thiol-dependent ubiquitinyl hydrolase activity +namespace: molecular_function +def: "Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin." [EC:3.4.19.12, GOC:bf, GOC:ka] +comment: 20160208: Renamed to thiol-dependent ubiquitinyl hydrolase activity +synonym: "ubiquitin C-terminal hydrolase" EXACT [EC:3.4.19.12] +synonym: "ubiquitinyl hydrolase 1 activity" EXACT [EC:3.4.19.12] +synonym: "ubiquitinyl hydrolase activity" BROAD [] +xref: EC:3.4.19.12 +xref: Reactome:R-HSA-3640872 "USP34 deubiquitinates AXIN1,AXIN2" +xref: Reactome:R-HSA-5688797 "ATXN3 family cleave Ub chains" +xref: Reactome:R-HSA-5688837 "ATXN3 deubiquitinates polyUb-PARK2" +xref: Reactome:R-HSA-5689950 "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN" +xref: Reactome:R-HSA-5689972 "USP2 deubiquitinates MDM2,MDM4" +xref: Reactome:R-HSA-5689973 "USP10,USP24,USP42 deubiquitinate TP53" +xref: Reactome:R-HSA-5690080 "USP3,SAGA deubiquitinate Histone H2A,H2B" +xref: Reactome:R-HSA-5690152 "USP5 cleaves polyubiquitin" +xref: Reactome:R-HSA-5690157 "USP16,USP21 deubiquitinate Histone H2A" +xref: Reactome:R-HSA-5690159 "USP21 deubiquitinates RIPK1,DDX58" +xref: Reactome:R-HSA-5690196 "USP8 deubiquitinates RNF128" +xref: Reactome:R-HSA-5690319 "UCHL1, UCHL3 cleave ubiquitin adducts" +xref: Reactome:R-HSA-5690759 "BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1" +xref: Reactome:R-HSA-5690790 "Histone H2A is dubiquitinated by the PR-DUB complex" +xref: Reactome:R-HSA-5691381 "MYSM1 deubiquitinates Histone H2A" +xref: Reactome:R-HSA-5696534 "USP18 deubiquitinates TAK1:TAB1" +xref: Reactome:R-HSA-5696564 "USP25 deubiquitinates DDX58" +xref: Reactome:R-HSA-5696600 "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1" +xref: Reactome:R-HSA-5696605 "USP12, USP26 deubiquitinate AR" +xref: Reactome:R-HSA-5696627 "CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG" +xref: Reactome:R-HSA-5696872 "USP30 deubiquitinates Ub-MOM proteins" +xref: Reactome:R-HSA-5696914 "USP28 deubiquitinates CLSPN and MYC" +xref: Reactome:R-HSA-5696945 "USP33 deubiquitinates CCP110,ARRB" +xref: Reactome:R-HSA-5696947 "USP47 deubiquitinates POLB" +xref: Reactome:R-HSA-5696958 "USP44 deubiquitinates CDC20" +xref: Reactome:R-HSA-5696960 "USP49 deubiquitinates H2B" +xref: Reactome:R-HSA-5696968 "USP20, USP33 deubiquitinate ADRB2" +xref: Reactome:R-HSA-5696997 "USP24 deubiquitinates DDB2" +xref: Reactome:R-HSA-5697009 "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2" +xref: Reactome:R-HSA-6781764 "USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1" +xref: Reactome:R-HSA-6781779 "USP13 deubiquitinates BECN1,USP10" +xref: Reactome:R-HSA-6781814 "USP19 deubiquitinates RNF123" +xref: Reactome:R-HSA-6781897 "USP11 deubiquitinates NFKBIA" +xref: Reactome:R-HSA-6782106 "USP10 deubiquitinates SNX3, CFTR" +xref: Reactome:R-HSA-6782628 "USP8 deubiquitinates STAM2:HGS" +xref: Reactome:R-HSA-6782820 "USP17 deubiquitinates SUDS3" +xref: Reactome:R-HSA-6783177 "USP21 deubiquitinates GATA3,IL33" +xref: Reactome:R-HSA-870437 "USP9X (FAM) deubiquitinates SMAD4" +xref: Reactome:R-HSA-8862184 "USP48 cleaves polyubiquitin" +xref: Reactome:R-HSA-8865182 "OTUD7A hydrolyses K11diUb" +xref: Reactome:R-HSA-8869456 "USP4 deubiquitinate TRAF2,TRAF6" +xref: Reactome:R-HSA-8873946 "OTUD3 deubiquitinates PTEN" +xref: Reactome:R-HSA-9033478 "USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin" +xref: Reactome:R-HSA-9033491 "USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin" +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity +is_a: GO:0101005 ! ubiquitinyl hydrolase activity +created_by: bf +creation_date: 2013-12-19T09:39:38Z + +[Term] +id: GO:0036460 +name: cellular response to cell envelope stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope." [GOC:imk, PMID:15101969, PMID:15882407] +synonym: "envelope stress response" EXACT [PMID:15882407] +is_a: GO:0033554 ! cellular response to stress +created_by: bf +creation_date: 2014-01-08T15:15:50Z + +[Term] +id: GO:0036461 +name: BLOC-2 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules." [GOC:bf, GOC:PARL, PMID:22511774] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2014-06-11T09:14:55Z + +[Term] +id: GO:0036462 +name: TRAIL-activated apoptotic signaling pathway +namespace: biological_process +def: "An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface." [GOC:bf, GOC:PARL, PMID:21785459] +synonym: "TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "TRAIL-induced apoptotic signaling pathway" EXACT [PMID:21785459] +synonym: "tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [PMID:21785459] +is_a: GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +created_by: bf +creation_date: 2014-06-11T09:18:41Z + +[Term] +id: GO:0036463 +name: TRAIL receptor activity +namespace: molecular_function +def: "Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death." [GOC:bf, GOC:PARL] +synonym: "tumor necrosis factor-related apoptosis-inducing ligand receptor" EXACT [PMID:21785459] +is_a: GO:0005035 ! death receptor activity +relationship: has_part GO:0045569 ! TRAIL binding +relationship: part_of GO:0036462 ! TRAIL-activated apoptotic signaling pathway +created_by: bf +creation_date: 2014-06-11T09:20:30Z + +[Term] +id: GO:0036464 +name: cytoplasmic ribonucleoprotein granule +namespace: cellular_component +def: "A ribonucleoprotein granule located in the cytoplasm." [GOC:bf, GOC:PARL, PMID:15121898] +synonym: "Staufen granule" NARROW [PMID:15121898] +is_a: GO:0035770 ! ribonucleoprotein granule +intersection_of: GO:0035770 ! ribonucleoprotein granule +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2014-06-18T09:44:44Z + +[Term] +id: GO:0036465 +name: synaptic vesicle recycling +namespace: biological_process +def: "The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane." [GOC:bf, GOC:pad, GOC:PARL, PMID:15217342, PMID:22026965, PMID:23245563] +synonym: "kiss-and-run synaptic vesicle recycling" NARROW [PMID:15217342] +synonym: "kiss-and-stay synaptic vesicle recycling" NARROW [PMID:152127342] +is_a: GO:0006810 ! transport +is_a: GO:0051649 ! establishment of localization in cell +relationship: part_of GO:0099504 ! synaptic vesicle cycle +created_by: bf +creation_date: 2014-06-26T11:03:08Z + +[Term] +id: GO:0036466 +name: synaptic vesicle recycling via endosome +namespace: biological_process +alt_id: GO:0099090 +def: "Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate." [GOC:aruk, GOC:bc, GOC:bf, GOC:dos, GOC:pad, GOC:PARL, PMID:15217342] +subset: goslim_synapse +synonym: "recycling endosome localization within postsynapse" EXACT [] +is_a: GO:0036465 ! synaptic vesicle recycling +is_a: GO:0046907 ! intracellular transport +relationship: part_of GO:0099532 ! synaptic vesicle endosomal processing +created_by: bf +creation_date: 2014-06-26T11:07:46Z + +[Term] +id: GO:0036467 +name: 5-hydroxy-L-tryptophan decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin." [GOC:bf, GOC:PARL, RHEA:18533] +synonym: "5-hydroxytryptophan decarboxylase activity" BROAD [EC:4.1.1.28] +xref: RHEA:18533 +is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:22:24Z + +[Term] +id: GO:0036468 +name: L-dopa decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine." [GOC:bf, GOC:PARL, RHEA:12272] +synonym: "4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [PMID:19703902] +synonym: "DDC activity" EXACT [PMID:19703902] +synonym: "DOPA decarboxylase activity" EXACT [EC:4.1.1.28] +xref: RHEA:12272 +is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:22:24Z + +[Term] +id: GO:0036469 +name: L-tryptophan decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine." [GOC:bf, GOC:PARL, RHEA:30339] +synonym: "L-tryptophan decarboxylase activity" EXACT [EC:4.1.1.105] +xref: EC:4.1.1.105 +xref: RHEA:30339 +is_a: GO:0004058 ! aromatic-L-amino-acid decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:22:24Z + +[Term] +id: GO:0036470 +name: tyrosine 3-monooxygenase activator activity +namespace: molecular_function +def: "Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity." [GOC:bf, GOC:PARL, PMID:19703902] +synonym: "TH activator activity" EXACT [PMID:19703902] +synonym: "tyrosine hydroxylase activator activity" EXACT [PMID:19703902] +is_a: GO:0008047 ! enzyme activator activity +relationship: part_of GO:1903178 ! positive regulation of tyrosine 3-monooxygenase activity +relationship: positively_regulates GO:0004511 ! tyrosine 3-monooxygenase activity +created_by: bf +creation_date: 2014-07-21T11:06:49Z + +[Term] +id: GO:0036471 +name: cellular response to glyoxal +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus." [GOC:bf, GOC:PARL] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0110096 ! cellular response to aldehyde +created_by: bf +creation_date: 2014-07-21T11:14:33Z + +[Term] +id: GO:0036472 +name: suppression by virus of host protein-protein interaction +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins." [GOC:bf, GOC:PARL, PMID:17297443] +synonym: "suppression by virus of host protein binding" EXACT [GOC:bf] +synonym: "suppression by virus of host protein interaction" EXACT [GOC:bf] +synonym: "suppression by virus of host protein:protein binding" EXACT [GOC:bf] +synonym: "suppression by virus of host protein:protein interaction" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: bf +creation_date: 2014-07-21T11:18:51Z + +[Term] +id: GO:0036473 +name: cell death in response to oxidative stress +namespace: biological_process +def: "Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus." [GOC:bf, GOC:PARL] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred in response to an oxidative stress stimulus, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0097468 'programmed cell death in response to reactive oxygen species'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. +is_a: GO:0008219 ! cell death +relationship: part_of GO:0034599 ! cellular response to oxidative stress +created_by: bf +creation_date: 2014-07-21T11:37:03Z + +[Term] +id: GO:0036474 +name: cell death in response to hydrogen peroxide +namespace: biological_process +def: "Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2)." [GOC:bf, GOC:PARL] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0010421 'hydrogen peroxide-mediated programmed cell death'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. +synonym: "cell death in response to H2O2" EXACT [GOC:bf] +synonym: "hydrogen peroxide-mediated cell death" RELATED [GOC:bf] +is_a: GO:0036473 ! cell death in response to oxidative stress +relationship: part_of GO:0070301 ! cellular response to hydrogen peroxide +created_by: bf +creation_date: 2014-07-21T11:42:28Z + +[Term] +id: GO:0036475 +name: neuron death in response to oxidative stress +namespace: biological_process +def: "Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus." [GOC:bf, GOC:PARL] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate. +synonym: "neuronal cell death in response to oxidative stress" EXACT [GOC:bf] +synonym: "oxidative stress-induced neuron death" EXACT [GOC:bf] +is_a: GO:0036473 ! cell death in response to oxidative stress +is_a: GO:0070997 ! neuron death +created_by: bf +creation_date: 2014-07-21T11:44:40Z + +[Term] +id: GO:0036476 +name: neuron death in response to hydrogen peroxide +namespace: biological_process +def: "Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2)." [GOC:bf, GOC:PARL] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate. +synonym: "hydrogen peroxide-induced neuron death" EXACT [GOC:bf] +synonym: "neuron death in response to H2O2" EXACT [GOC:bf] +synonym: "neuronal cell death in response to hydrogen peroxide" EXACT [GOC:bf] +is_a: GO:0036474 ! cell death in response to hydrogen peroxide +is_a: GO:0036475 ! neuron death in response to oxidative stress +created_by: bf +creation_date: 2014-07-21T11:46:31Z + +[Term] +id: GO:0036477 +name: somatodendritic compartment +namespace: cellular_component +def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL] +is_a: GO:0110165 ! cellular anatomical entity +created_by: bf +creation_date: 2014-07-24T10:06:19Z + +[Term] +id: GO:0036478 +name: L-dopa decarboxylase activator activity +namespace: molecular_function +def: "Interacts with and increases L-dopa decarboxylase activity." [GOC:bf, GOC:PARL] +comment: GO:0036478 is reserved for cases when the activator directly interacts with L-dopa decarboxylase. When activation of L-dopa decarboxylase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'positive regulation of L-dopa decarboxylase activity ; GO:1903200'. +synonym: "DDC activator activity" EXACT [GOC:bf] +is_a: GO:0008047 ! enzyme activator activity +relationship: part_of GO:1903200 ! positive regulation of L-dopa decarboxylase activity +relationship: positively_regulates GO:0036468 ! L-dopa decarboxylase activity +created_by: bf +creation_date: 2014-07-24T10:10:51Z + +[Term] +id: GO:0036479 +name: peroxidase inhibitor activity +namespace: molecular_function +def: "Interacts with, and stops, prevents or reduces the activity of a peroxidase." [GOC:bf, GOC:PARL] +comment: GO:0036479 is reserved for cases when the inhibitor directly interacts with the peroxidase. When inhibition of peroxidase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'negative regulation of peroxidase activity ; GO:2000469'. +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004601 ! peroxidase activity +relationship: part_of GO:2000469 ! negative regulation of peroxidase activity +created_by: bf +creation_date: 2014-07-24T10:14:45Z + +[Term] +id: GO:0036480 +name: neuron intrinsic apoptotic signaling pathway in response to oxidative stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered." [GOC:bf, GOC:PARL, PMID:23858059] +synonym: "neuron apoptosis in response to oxidative stress" RELATED [GOC:bf] +synonym: "oxidative stress-induced neuron apoptosis" BROAD [GOC:bf] +synonym: "oxidative stress-induced neuronal apoptosis" BROAD [GOC:bf] +is_a: GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: part_of GO:0036475 ! neuron death in response to oxidative stress +relationship: part_of GO:0051402 ! neuron apoptotic process +created_by: bf +creation_date: 2014-08-14T13:13:44Z + +[Term] +id: GO:0036481 +name: intrinsic apoptotic signaling pathway in response to hydrogen peroxide +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2)." [GOC:bf, GOC:PARL] +synonym: "H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:bf] +synonym: "hydrogen peroxide-induced apoptosis" BROAD [GOC:bf] +synonym: "hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:bf] +is_a: GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: part_of GO:0010421 ! hydrogen peroxide-mediated programmed cell death +created_by: bf +creation_date: 2014-08-14T13:19:21Z + +[Term] +id: GO:0036482 +name: neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide." [GOC:bf, GOC:PARL] +synonym: "H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "hydrogen peroxide-induced neuron apoptosis" BROAD [GOC:bf] +synonym: "hydrogen peroxide-induced neuronal apoptosis" BROAD [GOC:bf] +synonym: "neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:bf] +synonym: "neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:bf] +is_a: GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +is_a: GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: part_of GO:0036476 ! neuron death in response to hydrogen peroxide +created_by: bf +creation_date: 2014-08-14T13:23:32Z + +[Term] +id: GO:0036483 +name: neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:bf, GOC:PARL, PMID:21113145] +synonym: "endoplasmic reticulum stress-induced neuron apoptosis" BROAD [GOC:bf] +synonym: "endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "ER stress-induced neuron apoptosis" BROAD [GOC:bf] +synonym: "ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +is_a: GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: part_of GO:0051402 ! neuron apoptotic process +created_by: bf +creation_date: 2014-08-14T13:33:23Z + +[Term] +id: GO:0036484 +name: trunk neural crest cell migration +namespace: biological_process +def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] +synonym: "trunk NCC migration" EXACT [PMID:2387238] +is_a: GO:0001755 ! neural crest cell migration +relationship: part_of GO:0035290 ! trunk segmentation +created_by: bf +creation_date: 2014-08-26T15:27:44Z + +[Term] +id: GO:0036485 +name: dorsolateral trunk neural crest cell migration +namespace: biological_process +def: "The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] +synonym: "dorsolateral trunk NCC migration" EXACT [PMID:2387238] +is_a: GO:0036484 ! trunk neural crest cell migration +created_by: bf +creation_date: 2014-08-26T15:29:04Z + +[Term] +id: GO:0036486 +name: ventral trunk neural crest cell migration +namespace: biological_process +def: "The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta." [GOC:bf, GOC:mat, GOC:PARL, PMID:16319111, PMID:19386662] +synonym: "trunk NCC migration through anterior sclerotome" EXACT [PMID:19386662] +synonym: "trunk NCC migration within somite" EXACT [GOC:mat] +synonym: "ventral trunk NCC migration" EXACT [GOC:bf] +is_a: GO:0036484 ! trunk neural crest cell migration +created_by: bf +creation_date: 2014-08-26T15:30:16Z + +[Term] +id: GO:0036487 +name: nitric-oxide synthase inhibitor activity +namespace: molecular_function +def: "Interacts with, and stops, prevents or reduces the activity of nitric oxide synthase." [GOC:BHF, GOC:rl, PMID:17242280] +synonym: "nitric oxide synthase inhibitor activity" EXACT [GOC:bf] +synonym: "NOS inhibitor activity" EXACT [GOC:bf] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0030235 ! nitric-oxide synthase regulator activity +relationship: negatively_regulates GO:0004517 ! nitric-oxide synthase activity +created_by: bf +creation_date: 2014-09-09T15:07:20Z + +[Term] +id: GO:0036488 +name: CHOP-C/EBP complex +namespace: cellular_component +def: "A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors." [GOC:bf, GOC:PARL, PMID:1547942] +synonym: "CHOP-C/EBP dimer" EXACT [PMID:8657121] +synonym: "CHOP-C/EBP heterodimer" EXACT [PMID:8657121] +synonym: "GADD153-C/EBP complex" EXACT [PMID:8657121] +synonym: "GADD153-C/EBP-alpha complex" NARROW [PMID:8657121] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: bf +creation_date: 2014-11-06T13:18:49Z + +[Term] +id: GO:0036489 +name: neuromelanin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers." [GOC:bf, GOC:PARL, Wiki:Neuromelanin] +synonym: "neuromelanin anabolism" EXACT [GOC:bf] +synonym: "neuromelanin biosynthesis" EXACT [GOC:bf] +synonym: "neuromelanin formation" EXACT [GOC:bf] +synonym: "neuromelanin synthesis" EXACT [GOC:bf] +is_a: GO:0009059 ! macromolecule biosynthetic process +created_by: bf +creation_date: 2014-11-06T13:21:46Z + +[Term] +id: GO:0036490 +name: regulation of translation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242] +synonym: "regulation of translation in response to ER stress" EXACT [GOC:bf] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0043555 ! regulation of translation in response to stress +created_by: bf +creation_date: 2015-02-05T09:50:11Z + +[Term] +id: GO:0036491 +name: regulation of translation initiation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242] +synonym: "regulation of translation initiation in response to ER stress" EXACT [GOC:bf] +is_a: GO:0036490 ! regulation of translation in response to endoplasmic reticulum stress +is_a: GO:0043558 ! regulation of translational initiation in response to stress +created_by: bf +creation_date: 2015-02-05T09:52:13Z + +[Term] +id: GO:0036492 +name: eiF2alpha phosphorylation in response to endoplasmic reticulum stress +namespace: biological_process +def: "The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242] +synonym: "eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:bf] +synonym: "regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:bf] +is_a: GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation +is_a: GO:0036491 ! regulation of translation initiation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-05T09:53:21Z + +[Term] +id: GO:0036493 +name: positive regulation of translation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL] +synonym: "positive regulation of translation in response to ER stress" EXACT [GOC:bf] +is_a: GO:0032056 ! positive regulation of translation in response to stress +is_a: GO:0036490 ! regulation of translation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-05T10:09:51Z + +[Term] +id: GO:0036494 +name: positive regulation of translation initiation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL] +synonym: "positive regulation of translation initiation in response to ER stress" EXACT [GOC:bf] +is_a: GO:0032058 ! positive regulation of translational initiation in response to stress +is_a: GO:0036491 ! regulation of translation initiation in response to endoplasmic reticulum stress +is_a: GO:0036493 ! positive regulation of translation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-05T10:11:32Z + +[Term] +id: GO:0036495 +name: negative regulation of translation initiation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL] +synonym: "negative regulation of translation initiation in response to ER stress" RELATED [GOC:bf] +is_a: GO:0032057 ! negative regulation of translational initiation in response to stress +is_a: GO:0036491 ! regulation of translation initiation in response to endoplasmic reticulum stress +is_a: GO:1902010 ! negative regulation of translation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-05T10:13:38Z + +[Term] +id: GO:0036496 +name: regulation of translational initiation by eIF2 alpha dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha." [GOC:bf, GOC:PARL] +is_a: GO:0006470 ! protein dephosphorylation +is_a: GO:0032535 ! regulation of cellular component size +is_a: GO:0043558 ! regulation of translational initiation in response to stress +created_by: bf +creation_date: 2015-02-05T10:21:31Z + +[Term] +id: GO:0036497 +name: eIF2alpha dephosphorylation in response to endoplasmic reticulum stress +namespace: biological_process +def: "The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:16835242] +synonym: "eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:bf] +synonym: "regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:bf] +is_a: GO:0036491 ! regulation of translation initiation in response to endoplasmic reticulum stress +is_a: GO:0036496 ! regulation of translational initiation by eIF2 alpha dephosphorylation +created_by: bf +creation_date: 2015-02-05T10:24:18Z + +[Term] +id: GO:0036498 +name: IRE1-mediated unfolded protein response +namespace: biological_process +def: "A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB." [GOC:bf, GOC:PARL, PMID:22013210] +comment: Consider also annotating to 'eiF2alpha phosphorylation in response to endoplasmic reticulum stress ; GO:0036492' or its descendants. +synonym: "endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:bf] +synonym: "ERN1-mediated unfolded protein response" RELATED [HGNC:3449] +synonym: "inositol-requiring enzyme 1-mediated unfolded protein response" RELATED [HGNC:3449] +synonym: "inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [PMID:22013210] +synonym: "IRE1 branch of UPR" EXACT [GOC:bf] +synonym: "IRE1 signal transduction pathway" BROAD [GOC:bf] +synonym: "IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:bf] +synonym: "IRE1alpha unfolded protein response" NARROW [PMID:22013210] +synonym: "IRE1p unfolded protein response" NARROW [PMID:22013210] +synonym: "UPR signaling by IRE1 stress sensor" EXACT [GOC:bf] +is_a: GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: bf +creation_date: 2015-02-05T13:12:12Z + +[Term] +id: GO:0036499 +name: PERK-mediated unfolded protein response +namespace: biological_process +def: "A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity." [GOC:bf, GOC:PARL, PMID:22013210] +synonym: "EIF2AK3-mediated unfolded protein response" RELATED [HGNC:3255] +synonym: "endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:bf] +synonym: "eukaryotic translation initiation factor 2-alpha kinase 3-mediated unfolded protein response" RELATED [HGNC:3255] +synonym: "PERK branch of UPR" EXACT [GOC:bf] +synonym: "PERK signal transduction pathway" BROAD [GOC:bf] +synonym: "PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:bf] +synonym: "PKR-like ER kinase signal transduction" EXACT [PMID:22013210] +synonym: "UPR signaling by PERK stress sensor" EXACT [GOC:bf] +is_a: GO:0006984 ! ER-nucleus signaling pathway +is_a: GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: bf +creation_date: 2015-02-05T13:17:43Z + +[Term] +id: GO:0036500 +name: ATF6-mediated unfolded protein response +namespace: biological_process +def: "A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity." [GOC:bf, GOC:PARL, PMID:22013210] +synonym: "activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:bf] +synonym: "ATF6 branch of UPR" EXACT [GOC:bf] +synonym: "ATF6 signal transduction pathway" BROAD [GOC:bf] +synonym: "ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:bf] +synonym: "ATF6-alpha UPR branch" NARROW [GOC:bf] +synonym: "ATF6-beta UPR branch" NARROW [GOC:bf] +synonym: "endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:bf] +synonym: "UPR signaling by ATF6 stress sensor" EXACT [GOC:bf] +is_a: GO:0006984 ! ER-nucleus signaling pathway +is_a: GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: bf +creation_date: 2015-02-05T13:18:58Z + +[Term] +id: GO:0036501 +name: UFD1-NPL4 complex +namespace: cellular_component +def: "A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p." [GOC:bf, GOC:PARL, PMID:10811609, PMID:17289586] +synonym: "Npl4p-Ufd1p complex" EXACT [PMID:17289586] +synonym: "Ufd1-Npl4 binary complex" EXACT [PMID:10811609] +synonym: "Ufd1-Npl4 cofactor complex" EXACT [PMID:10811609] +synonym: "Ufd1/Npl4 complex" EXACT [PMID:10811609] +synonym: "UFD1L-NPLOC4 complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2015-05-14T10:59:43Z + +[Term] +id: GO:0036502 +name: Derlin-1-VIMP complex +namespace: cellular_component +def: "A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome." [GOC:bf, GOC:PARL, PMID:15215856, PMID:16186510] +synonym: "Derlin-1/VIMP complex" EXACT [PMID:15215856] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: bf +creation_date: 2015-05-14T11:40:45Z + +[Term] +id: GO:0036503 +name: ERAD pathway +namespace: biological_process +def: "The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome." [GOC:bf, GOC:PARL, PMID:20940304, PMID:21969857] +comment: ER-associated protein degradation (ERAD) pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M), and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by substrate ubiquitination and proteosomal-mediated degradation. In contrast the stress-induced homeostatically regulated protein degradation (SHRED) pathway (GO:0120174), although inducible by stress, targets diverse ER membrane, and cytosolic proteins as well as numerous other native proteins in the absence of stress. Stress results in the protease-mediated (Nma111p) generation of a Roq1p cleavage product that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. Although the SHRED pathway may contain some components in common with ERAD pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10, do not appear to be involved, and as such these pathways are currently considered to be distinct. +synonym: "endoplasmic reticulum-associated degradation" EXACT [PMID:22535891] +synonym: "endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:bf] +synonym: "ER-associated degradation pathway" RELATED [PMID:24699081] +synonym: "protein degradation by ERAD" EXACT [GOC:bf] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0010498 ! proteasomal protein catabolic process +is_a: GO:0034976 ! response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-05-14T11:43:06Z + +[Term] +id: GO:0036504 +name: Golgi membrane fusion +namespace: biological_process +def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691] +synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf] +synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609] +is_a: GO:0090174 ! organelle membrane fusion +relationship: part_of GO:0090168 ! Golgi reassembly +created_by: bf +creation_date: 2015-05-21T10:05:06Z + +[Term] +id: GO:0036505 +name: prosaposin receptor activity +namespace: molecular_function +def: "Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D)." [GOC:bf, GOC:PARL, PMID:23690594, PMID:9388493, PR:000031300] +synonym: "prosaposin-activated receptor activity" EXACT [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity +created_by: bf +creation_date: 2015-06-11T10:13:10Z + +[Term] +id: GO:0036506 +name: maintenance of unfolded protein +namespace: biological_process +def: "Maintaining a protein in an unfolded, soluble state." [GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, PMID:21636303] +is_a: GO:0031647 ! regulation of protein stability +created_by: bf +creation_date: 2015-06-11T10:17:36Z + +[Term] +id: GO:0036507 +name: protein demannosylation +namespace: biological_process +def: "The removal of one or more mannose residues from a mannosylated protein." [GOC:bf, GOC:PARL, PMID:25092655] +comment: Consider also annotating to the term 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "protein de-mannosylation" EXACT [GOC:bf] +is_a: GO:0006517 ! protein deglycosylation +relationship: has_part GO:0015923 ! mannosidase activity +created_by: bf +creation_date: 2015-06-11T13:57:01Z + +[Term] +id: GO:0036508 +name: protein alpha-1,2-demannosylation +namespace: biological_process +def: "The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein." [GOC:bf, GOC:PARL, PMID:21062743, PMID:25092655] +comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "glycoprotein mannose trimming" RELATED [GOC:bf] +synonym: "mannose trimming" BROAD [PMID:21062743] +is_a: GO:0036507 ! protein demannosylation +relationship: has_part GO:0004571 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity +created_by: bf +creation_date: 2015-06-11T13:58:50Z + +[Term] +id: GO:0036509 +name: trimming of terminal mannose on B branch +namespace: biological_process +def: "The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum." [GOC:bf, GOC:PARL, KEGG_REACTION:R06722, PMID:22160784] +comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "conversion of (Man)9(GlcNAc)2 to (Man)8B(GlcNAc)2" RELATED [PMID:22160784] +synonym: "conversion of M9 to M8B" RELATED [PMID:25092655] +synonym: "glycoprotein mannose trimming on B branch" EXACT [GOC:bf] +xref: KEGG_REACTION:R06722 +is_a: GO:1904380 ! endoplasmic reticulum mannose trimming +created_by: bf +creation_date: 2015-06-11T14:02:44Z + +[Term] +id: GO:0036510 +name: trimming of terminal mannose on C branch +namespace: biological_process +def: "The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum." [GOC:bf, GOC:PARL, PMID:20065073] +comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2" RELATED [PMID:20065073] +synonym: "conversion of M9 to M8C" RELATED [GOC:bf] +synonym: "glycoprotein mannose trimming on C branch" EXACT [GOC:bf] +is_a: GO:1904380 ! endoplasmic reticulum mannose trimming +created_by: bf +creation_date: 2015-06-11T14:10:52Z + +[Term] +id: GO:0036511 +name: trimming of first mannose on A branch +namespace: biological_process +def: "The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum." [GOC:bf, GOC:PARL, PMID:12829701] +comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2" RELATED [GOC:bf] +synonym: "conversion of M9 to M8A" RELATED [GOC:bf] +synonym: "glycoprotein mannose trimming on A branch" BROAD [GOC:bf] +is_a: GO:1904380 ! endoplasmic reticulum mannose trimming +created_by: bf +creation_date: 2015-06-11T14:14:03Z + +[Term] +id: GO:0036512 +name: trimming of second mannose on A branch +namespace: biological_process +def: "The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum." [GOC:bf, GOC:PARL, PMID:12829701] +comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. +synonym: "conversion of (Man)8A(GlcNAc)2 to (Man)7AA(GlcNAc)2" RELATED [GOC:bf] +synonym: "conversion of M8A to M7AA" RELATED [GOC:bf] +synonym: "glycoprotein mannose trimming on A branch" BROAD [GOC:bf] +is_a: GO:1904380 ! endoplasmic reticulum mannose trimming +created_by: bf +creation_date: 2015-06-11T14:16:40Z + +[Term] +id: GO:0036513 +name: Derlin-1 retrotranslocation complex +namespace: cellular_component +def: "A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel." [GOC:bf, GOC:PARL, PMID:15215856, PMID:16186510] +comment: The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process. +synonym: "Derlin-1 complex" EXACT [PMID:18555783] +synonym: "Derlin-1 protein dislocation complex" EXACT [PMID:18555783] +synonym: "Derlin-1 retro-translocation complex" EXACT [GOC:bf] +synonym: "Derlin-1 retrotranslocon" EXACT [GOC:bf] +synonym: "ERAD protein dislocation complex" EXACT [PMID:18555783] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: bf +creation_date: 2015-07-01T10:17:30Z + +[Term] +id: GO:0036514 +name: dopaminergic neuron axon guidance +namespace: biological_process +def: "The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues." [GOC:bf, GOC:PARL, PMID:21106844, PMID:23517308] +synonym: "DA axon guidance" EXACT [PMID:23517308] +synonym: "dopaminergic axon guidance" EXACT [GOC:bf] +synonym: "mdDA axon guidance" EXACT [PMID:21106844] +is_a: GO:0007411 ! axon guidance +created_by: bf +creation_date: 2015-12-17T11:14:20Z + +[Term] +id: GO:0036515 +name: serotonergic neuron axon guidance +namespace: biological_process +def: "The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues." [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844] +synonym: "5-HT axon guidance" EXACT [GOC:bf, PMID:21106844] +synonym: "serotonergic axon guidance" EXACT [GOC:bf] +is_a: GO:0007411 ! axon guidance +created_by: bf +creation_date: 2015-12-17T11:15:54Z + +[Term] +id: GO:0036516 +name: chemoattraction of dopaminergic neuron axon +namespace: biological_process +def: "The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal." [GOC:bf, GOC:PARL, PMID:21106844] +synonym: "chemoattraction of DA axon" EXACT [GOC:bf] +synonym: "chemoattraction of dopaminergic axon" EXACT [GOC:bf] +is_a: GO:0061642 ! chemoattraction of axon +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0036514 ! dopaminergic neuron axon guidance +relationship: part_of GO:0036514 ! dopaminergic neuron axon guidance +created_by: bf +creation_date: 2015-12-17T11:23:11Z + +[Term] +id: GO:0036517 +name: chemoattraction of serotonergic neuron axon +namespace: biological_process +def: "The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal." [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844] +synonym: "chemoattraction of 5-HT axon" EXACT [GOC:bf, PMID:21106844] +synonym: "chemoattraction of serotonergic axon" EXACT [GOC:bf] +is_a: GO:0061642 ! chemoattraction of axon +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0036515 ! serotonergic neuron axon guidance +relationship: part_of GO:0036515 ! serotonergic neuron axon guidance +created_by: bf +creation_date: 2015-12-17T11:26:03Z + +[Term] +id: GO:0036518 +name: chemorepulsion of dopaminergic neuron axon +namespace: biological_process +def: "The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." [GOC:bf, GOC:PARL, PMID:21106844, PMID:23517308] +synonym: "chemorepulsion of DA axon" EXACT [GOC:bf, PMID:23517308] +synonym: "chemorepulsion of dopaminergic axon" RELATED [GOC:bf] +is_a: GO:0061643 ! chemorepulsion of axon +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0036514 ! dopaminergic neuron axon guidance +relationship: part_of GO:0036514 ! dopaminergic neuron axon guidance +created_by: bf +creation_date: 2015-12-17T11:29:09Z + +[Term] +id: GO:0036519 +name: chemorepulsion of serotonergic neuron axon +namespace: biological_process +def: "The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844] +synonym: "chemorepulsion of 5-HT axon" EXACT [GOC:bf, PMID:21106844] +synonym: "chemorepulsion of serotonergic axon" RELATED [GOC:bf] +is_a: GO:0061643 ! chemorepulsion of axon +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0036515 ! serotonergic neuron axon guidance +relationship: part_of GO:0036515 ! serotonergic neuron axon guidance +created_by: bf +creation_date: 2015-12-17T11:31:16Z + +[Term] +id: GO:0036520 +name: astrocyte-dopaminergic neuron signaling +namespace: biological_process +def: "Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron." [GOC:bf, GOC:PARL, PMID:12794311, PMID:21752258] +synonym: "astrocyte-dopaminergic neuron cell signaling" EXACT [GOC:bf] +synonym: "dopaminergic neuron-astrocyte crosstalk" RELATED [PMID:21752258] +synonym: "mesencephalic dopaminergic neuron-astrocyte crosstalk" NARROW [PMID:21752258] +synonym: "midbrain dopaminergic neuron-astrocyte crosstalk" NARROW [PMID:21752258] +is_a: GO:0150098 ! glial cell-neuron signaling +created_by: bf +creation_date: 2016-02-29T14:05:47Z + +[Term] +id: GO:0036521 +name: modulation by symbiont of host protein localization to phagocytic vesicle +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:PARL, PMID:25063865] +synonym: "modulation by symbiont of host protein localisation to phagosome" RELATED [GOC:bf] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:1905169 ! regulation of protein localization to phagocytic vesicle +created_by: bf +creation_date: 2016-06-06T14:47:10Z + +[Term] +id: GO:0036522 +name: negative regulation by symbiont of host protein localization to phagocytic vesicle +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:PARL, PMID:25063865] +synonym: "disruption of host protein localisation to phagosome" EXACT [GOC:bf] +synonym: "inhibition of host protein localisation to phagosome" EXACT [GOC:bf] +synonym: "suppression of host protein localisation to phagosome" EXACT [GOC:bf] +is_a: GO:0036521 ! modulation by symbiont of host protein localization to phagocytic vesicle +is_a: GO:1905170 ! negative regulation of protein localization to phagocytic vesicle +created_by: bf +creation_date: 2016-06-06T14:49:51Z + +[Term] +id: GO:0036523 +name: induction by symbiont of host cytokine secretion +namespace: biological_process +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine secretion in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:PARL, PMID:25063865] +synonym: "induction by symbiont of host cytokine secretion" RELATED [PMID:25063865] +synonym: "positive regulation by symbiont of host cytokine secretion" EXACT [] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0052390 ! induction by symbiont of host innate immune response +created_by: bf +creation_date: 2016-06-06T14:53:54Z + +[Term] +id: GO:0036524 +name: protein deglycase activity +namespace: molecular_function +def: "Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein." [GOC:bf, GOC:PARL, MetaCyc:RXN-17630, MetaCyc:RXN-17632, MetaCyc:RXN-17634, PMID:14568004, PMID:25416785, PMID:26873906, RHEA:49548, RHEA:49552, RHEA:49556] +synonym: "protein deglycating enzyme" RELATED [PMID:26873906] +is_a: GO:0016836 ! hydro-lyase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0036525 ! protein deglycation +created_by: bf +creation_date: 2016-08-04T10:23:33Z + +[Term] +id: GO:0036525 +name: protein deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] +comment: Glycation is a non enzymatic covalent addition of a sugar or dicarbonyl (methylglyoxal, glyoxal) to a protein. Deglycation repairs the glycated amino acids. +synonym: "glycated protein repair" RELATED [PMID:25416785] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0030091 ! protein repair +created_by: bf +creation_date: 2016-08-04T10:28:54Z + +[Term] +id: GO:0036526 +name: peptidyl-cysteine deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] +synonym: "deglycation of N-acetylcysteine" RELATED [PMID:25416785] +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0036525 ! protein deglycation +created_by: bf +creation_date: 2016-08-04T10:35:25Z + +[Term] +id: GO:0036527 +name: peptidyl-arginine deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] +synonym: "deglycation of N-acetylarginine" RELATED [PMID:25416785] +is_a: GO:0018195 ! peptidyl-arginine modification +is_a: GO:0036525 ! protein deglycation +created_by: bf +creation_date: 2016-08-04T10:36:30Z + +[Term] +id: GO:0036528 +name: peptidyl-lysine deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] +synonym: "deglycation of N-acetyllysine" RELATED [PMID:25416785] +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0036525 ! protein deglycation +created_by: bf +creation_date: 2016-08-04T10:37:12Z + +[Term] +id: GO:0036529 +name: protein deglycation, glyoxal removal +namespace: biological_process +def: "The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein." [GOC:bf, GOC:PARL, PMID:25416785] +synonym: "protein deglycation of glyoxal-glycated protein" RELATED [PMID:25416785] +is_a: GO:0036525 ! protein deglycation +is_a: GO:0046295 ! glycolate biosynthetic process +is_a: GO:1903189 ! glyoxal metabolic process +created_by: bf +creation_date: 2016-08-04T10:41:25Z + +[Term] +id: GO:0036530 +name: protein deglycation, methylglyoxal removal +namespace: biological_process +def: "The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein." [GOC:bf, GOC:PARL, PMID:25416785] +synonym: "protein deglycation of methylglyoxal-glycated protein" RELATED [PMID:25416785] +is_a: GO:0009438 ! methylglyoxal metabolic process +is_a: GO:0019249 ! lactate biosynthetic process +is_a: GO:0036525 ! protein deglycation +created_by: bf +creation_date: 2016-08-04T10:42:26Z + +[Term] +id: GO:0036531 +name: glutathione deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine." [GOC:bf, GOC:PARL, PMID:25416785] +is_a: GO:0006749 ! glutathione metabolic process +created_by: bf +creation_date: 2016-08-04T10:45:27Z + +[Term] +id: GO:0038001 +name: paracrine signaling +namespace: biological_process +def: "The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other." [GOC:mtg_signaling_feb11, ISBN:3527303782] +comment: This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from endocrine signaling. +synonym: "paracrine signalling" EXACT [GOC:bf] +is_a: GO:0007267 ! cell-cell signaling +created_by: bf +creation_date: 2011-02-25T02:11:00Z + +[Term] +id: GO:0038002 +name: endocrine signaling +namespace: biological_process +def: "The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other." [GOC:mtg_signaling_feb11, ISBN:0199264678, ISBN:3527303782] +comment: This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from paracrine signaling. +synonym: "endocrine signalling" EXACT [GOC:bf] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0050886 ! endocrine process +created_by: bf +creation_date: 2011-02-25T02:12:19Z + +[Term] +id: GO:0038003 +name: opioid receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands." [GOC:bf, PMID:20494127] +synonym: "opioid receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2011-03-03T02:00:02Z + +[Term] +id: GO:0038004 +name: epidermal growth factor receptor ligand maturation +namespace: biological_process +alt_id: GO:0038005 +def: "Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor." [GOC:signaling, PMID:11672524, PMID:11672525] +synonym: "EGFR ligand maturation" EXACT [GOC:bf] +synonym: "EGFR ligand maturation by peptide bond cleavage" NARROW [GOC:bf] +synonym: "EGFR ligand processing" NARROW [GOC:bf] +synonym: "epidermal growth factor receptor ligand processing" RELATED [GOC:bf] +synonym: "peptide bond cleavage involved in EGFR ligand maturation" NARROW [GOC:bf] +synonym: "peptide bond cleavage involved in epidermal growth factor receptor ligand maturation" RELATED [] +is_a: GO:0016486 ! peptide hormone processing +relationship: has_part GO:0006509 ! membrane protein ectodomain proteolysis +created_by: bf +creation_date: 2011-06-07T03:08:41Z + +[Term] +id: GO:0038006 +name: netrin receptor activity involved in chemoattraction +namespace: molecular_function +def: "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin." [GOC:signaling] +synonym: "attractive netrin receptor activity" EXACT [GOC:bf] +synonym: "netrin receptor activity involved in positive chemotaxis" EXACT [GOC:bf] +is_a: GO:0005042 ! netrin receptor activity +intersection_of: GO:0005042 ! netrin receptor activity +intersection_of: part_of GO:0050918 ! positive chemotaxis +relationship: part_of GO:0050918 ! positive chemotaxis +created_by: bf +creation_date: 2011-06-10T02:22:29Z + +[Term] +id: GO:0038007 +name: netrin-activated signaling pathway +namespace: biological_process +def: "A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance." [GOC:signaling, PMID:10399919, PMID:15960985, PMID:19785719, PMID:20108323] +synonym: "netrin signaling pathway" EXACT [GOC:bf] +synonym: "netrin-activated signal transduction pathway" EXACT [GOC:bf] +synonym: "netrin-activated signalling pathway" EXACT [GOC:bf] +synonym: "netrin-mediated signaling pathway" EXACT [GOC:bf] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2011-06-10T02:24:59Z + +[Term] +id: GO:0038008 +name: TRAF-mediated signal transduction +namespace: biological_process +def: "The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components." [GOC:bf, PMID:19918944, PMID:20596822] +synonym: "TRAF signaling" EXACT [GOC:bf] +synonym: "TRAF-mediated intracellular signaling" EXACT [GOC:bf] +synonym: "TRAF-mediated signaling" EXACT [GOC:bf] +synonym: "TRAF-mediated signalling" EXACT [GOC:bf] +synonym: "tumor necrosis factor receptor-associated factor signal transduction" EXACT [GOC:bf] +synonym: "tumor necrosis factor receptor-associated factor signaling" EXACT [GOC:bf] +is_a: GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2011-06-22T04:01:54Z + +[Term] +id: GO:0038009 +name: regulation of signal transduction by receptor internalization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway." [GOC:bf, GOC:signaling, PMID:17011816, PMID:19696798] +synonym: "regulation of signaling pathway by receptor endocytosis" EXACT [GOC:bf] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0031623 ! receptor internalization +intersection_of: GO:0031623 ! receptor internalization +intersection_of: regulates GO:0007165 ! signal transduction +created_by: bf +creation_date: 2011-06-23T03:28:47Z + +[Term] +id: GO:0038010 +name: positive regulation of signal transduction by receptor internalization +namespace: biological_process +def: "Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms." [GOC:bf, GOC:signaling, PMID:17908284, PMID:19696798] +synonym: "positive regulation of signaling pathway by receptor endocytosis" EXACT [GOC:bf] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0038009 ! regulation of signal transduction by receptor internalization +intersection_of: GO:0031623 ! receptor internalization +intersection_of: positively_regulates GO:0007165 ! signal transduction +created_by: bf +creation_date: 2011-06-23T03:37:10Z + +[Term] +id: GO:0038011 +name: negative regulation of signal transduction by receptor internalization +namespace: biological_process +def: "Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands." [GOC:bf, GOC:signaling, PMID:17908284, PMID:19696798] +synonym: "negative regulation of signaling pathway by receptor endocytosis" EXACT [GOC:bf] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0038009 ! regulation of signal transduction by receptor internalization +intersection_of: GO:0031623 ! receptor internalization +intersection_of: negatively_regulates GO:0007165 ! signal transduction +created_by: bf +creation_date: 2011-06-23T03:39:06Z + +[Term] +id: GO:0038012 +name: negative regulation of Wnt signaling pathway by Wnt receptor internalization +namespace: biological_process +def: "Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction." [GOC:bf, GOC:BHF, GOC:rl, PMID:17908284, PMID:19643732] +synonym: "ligand-dependent internalization of Frizzled" NARROW [PMID:19643732] +synonym: "negative regulation of Wnt receptor signaling pathway by Wnt receptor endocytosis" NARROW [GOC:bf] +synonym: "negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization" EXACT [] +synonym: "negative regulation of Wnt receptor signalling pathway by Wnt receptor internalization" EXACT [GOC:mah] +synonym: "negative regulation of Wnt-activated signaling pathway by Wnt receptor internalization" EXACT [GOC:signaling] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:0038011 ! negative regulation of signal transduction by receptor internalization +is_a: GO:0038017 ! Wnt receptor internalization +intersection_of: GO:0038017 ! Wnt receptor internalization +intersection_of: negatively_regulates GO:0016055 ! Wnt signaling pathway +created_by: bf +creation_date: 2011-06-23T03:57:59Z + +[Term] +id: GO:0038013 +name: positive regulation of Wnt signaling pathway by Wnt receptor internalization +namespace: biological_process +def: "Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway." [GOC:bf, GOC:signaling, PMID:17908284] +synonym: "positive regulation of Wnt receptor signaling pathway by Frizzled internalization" RELATED [] +synonym: "positive regulation of Wnt receptor signaling pathway by LRP6 internalization" NARROW [GOC:bf] +synonym: "positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization" EXACT [] +synonym: "positive regulation of Wnt receptor signalling pathway by Wnt receptor endocytosis" EXACT [GOC:bf] +synonym: "positive regulation of Wnt-activated signaling pathway by Wnt receptor internalization" RELATED [GOC:signaling] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:0038010 ! positive regulation of signal transduction by receptor internalization +is_a: GO:0038017 ! Wnt receptor internalization +intersection_of: GO:0038017 ! Wnt receptor internalization +intersection_of: positively_regulates GO:0016055 ! Wnt signaling pathway +created_by: bf +creation_date: 2011-06-23T04:02:21Z + +[Term] +id: GO:0038014 +name: negative regulation of insulin receptor signaling pathway by insulin receptor internalization +namespace: biological_process +def: "Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation." [GOC:bf, GOC:signaling, PMID:18492485, PMID:7821727, PMID:7978876, PMID:9609114] +synonym: "agonist-stimulated insulin receptor internalization" BROAD [PMID:18492485] +synonym: "negative regulation of insulin receptor signalling pathway by insulin receptor internalization" EXACT [GOC:mah] +is_a: GO:0038011 ! negative regulation of signal transduction by receptor internalization +is_a: GO:0038016 ! insulin receptor internalization +is_a: GO:0046627 ! negative regulation of insulin receptor signaling pathway +intersection_of: GO:0038016 ! insulin receptor internalization +intersection_of: negatively_regulates GO:0008286 ! insulin receptor signaling pathway +created_by: bf +creation_date: 2011-06-23T04:08:31Z + +[Term] +id: GO:0038015 +name: positive regulation of insulin receptor signaling pathway by insulin receptor internalization +namespace: biological_process +def: "Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane." [GOC:bf, GOC:signaling, PMID:9609114] +synonym: "positive regulation of insulin receptor signalling pathway by insulin receptor internalization" EXACT [GOC:mah] +is_a: GO:0038010 ! positive regulation of signal transduction by receptor internalization +is_a: GO:0038016 ! insulin receptor internalization +is_a: GO:0046628 ! positive regulation of insulin receptor signaling pathway +intersection_of: GO:0038016 ! insulin receptor internalization +intersection_of: positively_regulates GO:0008286 ! insulin receptor signaling pathway +created_by: bf +creation_date: 2011-06-23T04:20:11Z + +[Term] +id: GO:0038016 +name: insulin receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell." [GOC:bf, PMID:3907718, PMID:9609114] +synonym: "insulin receptor endocytosis" BROAD [GOC:bf] +is_a: GO:0031623 ! receptor internalization +created_by: bf +creation_date: 2011-06-23T04:24:52Z + +[Term] +id: GO:0038017 +name: Wnt receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell." [GOC:bf, PMID:17908284] +synonym: "Wnt receptor endocytosis" BROAD [GOC:bf] +is_a: GO:0031623 ! receptor internalization +created_by: bf +creation_date: 2011-06-23T04:25:47Z + +[Term] +id: GO:0038018 +name: Wnt receptor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation." [GOC:BHF, GOC:rl, GOC:signaling, PMID:19643732] +synonym: "Frizzled degradation" NARROW [PMID:19643732] +synonym: "negative regulation of Wnt receptor signaling pathway by Wnt receptor degradation" EXACT [GOC:bf] +synonym: "Wnt receptor breakdown" EXACT [GOC:bf] +synonym: "Wnt receptor catabolism" EXACT [GOC:bf] +synonym: "Wnt receptor degradation" RELATED [GOC:bf] +is_a: GO:0032801 ! receptor catabolic process +relationship: part_of GO:0030178 ! negative regulation of Wnt signaling pathway +created_by: bf +creation_date: 2011-06-23T04:38:12Z + +[Term] +id: GO:0038019 +name: Wnt receptor recycling +namespace: biological_process +def: "The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation." [GOC:bf, GOC:signaling, PMID:19643732] +synonym: "Frizzled recycling" NARROW [PMID:19643732] +is_a: GO:0001881 ! receptor recycling +relationship: part_of GO:0030177 ! positive regulation of Wnt signaling pathway +created_by: bf +creation_date: 2011-06-23T04:46:11Z + +[Term] +id: GO:0038020 +name: insulin receptor recycling +namespace: biological_process +def: "The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation." [GOC:bf, GOC:signaling, PMID:3907718] +is_a: GO:0001881 ! receptor recycling +relationship: part_of GO:0046628 ! positive regulation of insulin receptor signaling pathway +created_by: bf +creation_date: 2011-06-23T04:52:05Z + +[Term] +id: GO:0038021 +name: leptin receptor activity +namespace: molecular_function +def: "Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:signaling, PMID:9102398, Wikipedia:Leptin_receptor] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0033210 ! leptin-mediated signaling pathway +created_by: bf +creation_date: 2011-06-27T01:36:45Z + +[Term] +id: GO:0038022 +name: G protein-coupled olfactory receptor activity +namespace: molecular_function +def: "Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:sart, PMID:21041441] +synonym: "G-protein coupled odorant receptor activity" EXACT [GOC:bf, PMID:21041441] +synonym: "G-protein coupled olfactory receptor activity" EXACT [] +synonym: "odorant receptor activity, G-protein coupled" NARROW [GOC:bf, PMID:21041441] +synonym: "olfactory receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0004984 ! olfactory receptor activity +created_by: bf +creation_date: 2011-07-01T11:23:51Z + +[Term] +id: GO:0038023 +name: signaling receptor activity +namespace: molecular_function +alt_id: GO:0004872 +alt_id: GO:0019041 +def: "Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:bf, GOC:signaling] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +subset: goslim_mouse +subset: goslim_pir +subset: goslim_plant +synonym: "receptor activity" BROAD [] +synonym: "receptor activity involved in signal transduction" EXACT [GOC:bf] +is_a: GO:0060089 ! molecular transducer activity +created_by: bf +creation_date: 2011-08-01T02:45:27Z + +[Term] +id: GO:0038024 +name: cargo receptor activity +namespace: molecular_function +def: "Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles." [PMID:15239958, PMID:27903609] +comment: Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857. +synonym: "endocytic receptor activity" NARROW [GOC:signaling, ISBN:0123645387, PMID:12671190] +synonym: "receptor activity" BROAD [] +synonym: "receptor activity involved in receptor-mediated endocytosis" NARROW [GOC:bf] +synonym: "transport receptor activity" BROAD [GOC:signaling] +is_a: GO:0003674 ! molecular_function +relationship: has_part GO:0060090 ! molecular adaptor activity +relationship: part_of GO:0006897 ! endocytosis +created_by: bf +creation_date: 2011-08-01T02:50:45Z + +[Term] +id: GO:0038025 +name: reelin receptor activity +namespace: molecular_function +def: "Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, PMID:12827279, PMID:20223215, PR:000013879] +synonym: "reeler receptor activity" EXACT [PR:000013879] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: part_of GO:0038026 ! reelin-mediated signaling pathway +created_by: bf +creation_date: 2011-08-02T12:01:25Z + +[Term] +id: GO:0038026 +name: reelin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, PMID:12827279, PMID:20223215, PR:000013879] +synonym: "reeler-mediated signaling pathway" EXACT [GOC:bf, PR:000013879] +synonym: "reelin-mediated signal transduction pathway" EXACT [GOC:bf] +synonym: "reelin-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2011-08-02T02:06:18Z + +[Term] +id: GO:0038027 +name: apolipoprotein A-I-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:signaling, PMID:16443932] +synonym: "apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2011-08-02T02:13:41Z + +[Term] +id: GO:0038028 +name: insulin receptor signaling pathway via phosphatidylinositol 3-kinase +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade." [GOC:bf, GOC:signaling, PMID:19322168, PMID:20696212] +synonym: "insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade" RELATED [] +synonym: "insulin receptor signaling pathway via PI3K cascade" EXACT [GOC:bf] +synonym: "insulin receptor signaling via PI3K" EXACT [GOC:bf] +synonym: "insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade" EXACT [GOC:mah] +is_a: GO:0008286 ! insulin receptor signaling pathway +relationship: has_part GO:0014065 ! phosphatidylinositol 3-kinase signaling +created_by: bf +creation_date: 2011-09-08T10:35:14Z + +[Term] +id: GO:0038029 +name: epidermal growth factor receptor signaling pathway via MAPK cascade +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade." [GOC:bf, GOC:signaling, PMID:21167805] +synonym: "EGFR signaling pathway via MAPKKK cascade" EXACT [GOC:bf] +synonym: "EGFR signaling via MAPKKK cascade" EXACT [GOC:bf] +synonym: "EGFR/MAPK signaling" EXACT [GOC:bf] +synonym: "epidermal growth factor receptor signaling pathway via MAPKKK cascade" EXACT [GOC:signaling] +synonym: "epidermal growth factor receptor signalling pathway via MAPKKK cascade" EXACT [GOC:bf] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: has_part GO:0000165 ! MAPK cascade +created_by: bf +creation_date: 2011-09-08T10:53:01Z + +[Term] +id: GO:0038030 +name: non-canonical Wnt signaling pathway via MAPK cascade +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade." [GOC:BHF, GOC:signaling, GOC:vk, PMID:17720811] +synonym: "non-canonical Wnt receptor signaling pathway via MAPK cascade" EXACT [] +synonym: "non-canonical Wnt receptor signaling pathway via MAPK signaling" EXACT [GOC:bf] +synonym: "non-canonical Wnt receptor signaling pathway via MAPKKK cascade" EXACT [GOC:signaling] +synonym: "non-canonical Wnt receptor signalling pathway via MAPKKK cascade" EXACT [GOC:bf] +synonym: "non-canonical Wnt-activated signaling pathway via MAPK cascade" EXACT [GOC:signaling] +is_a: GO:0035567 ! non-canonical Wnt signaling pathway +relationship: has_part GO:0000165 ! MAPK cascade +created_by: bf +creation_date: 2011-09-08T01:46:07Z + +[Term] +id: GO:0038031 +name: non-canonical Wnt signaling pathway via JNK cascade +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade." [GOC:BHF, GPC:rl, PMID:19137009, PMID:20032469] +synonym: "non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [] +synonym: "non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:bf] +synonym: "non-canonical Wnt-activated signaling pathway via JNK cascade" EXACT [GOC:signaling] +is_a: GO:0038030 ! non-canonical Wnt signaling pathway via MAPK cascade +relationship: has_part GO:0007254 ! JNK cascade +created_by: bf +creation_date: 2011-09-08T01:57:10Z + +[Term] +id: GO:0038032 +name: termination of G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal." [GOC:bf, GOC:signaling] +synonym: "termination of G-protein coupled receptor signaling pathway" EXACT [] +synonym: "termination of G-protein coupled receptor signalling pathway" EXACT [GOC:mah] +synonym: "termination of GPCR signaling pathway" EXACT [GOC:bf] +is_a: GO:0023021 ! termination of signal transduction +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2011-09-16T10:31:21Z + +[Term] +id: GO:0038033 +name: positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis." [GOC:bf, GOC:BHF, GOC:rl, PMID:21245381] +synonym: "positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of endothelial cell chemotaxis by VEGF/VEGFR signaling pathway" EXACT [GOC:bf] +synonym: "vascular endothelial growth factor receptor signaling pathway involved in endothelial cell chemotaxis" RELATED [GOC:bf] +synonym: "VEGF-mediated chemotactic endothelial cell migration" BROAD [GOC:bf, PMID:21245381] +synonym: "VEGF-VEGFR-induced endothelial cell chemotaxis" EXACT [GOC:bf] +is_a: GO:0038089 ! positive regulation of cell migration by vascular endothelial growth factor signaling pathway +is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +is_a: GO:2001028 ! positive regulation of endothelial cell chemotaxis +created_by: bf +creation_date: 2011-09-19T02:36:37Z + +[Term] +id: GO:0038034 +name: signal transduction in absence of ligand +namespace: biological_process +def: "A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor." [GOC:al, GOC:ppm, GOC:pr, PMID:15044679] +synonym: "addiction receptor signaling pathway" BROAD [PMID:15044679] +synonym: "basal signaling" NARROW [GOC:al] +synonym: "dependence receptor signaling pathway" BROAD [PMID:15044679] +synonym: "negative signal transduction" RELATED [PMID:15044679] +synonym: "non-classical signal transduction" BROAD [PMID:15044679] +synonym: "signal transduction in absence of agonist" EXACT [GOC:bf] +is_a: GO:0007165 ! signal transduction +created_by: bf +creation_date: 2011-10-26T02:21:03Z + +[Term] +id: GO:0038035 +name: G protein-coupled receptor signaling in absence of ligand +namespace: biological_process +def: "A series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist." [GOC:al, PMID:12402500, PMID:17629961] +comment: This term is intended for use by G protein-coupled receptors which signal at a low-level in the absence of agonist binding. +synonym: "basal G-protein coupled receptor signaling" NARROW [GOC:al] +synonym: "G-protein coupled receptor signaling in absence of agonist" EXACT [GOC:bf] +synonym: "G-protein coupled receptor signaling in absence of ligand" EXACT [] +synonym: "G-protein coupled receptor signalling in absence of ligand" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0038034 ! signal transduction in absence of ligand +created_by: bf +creation_date: 2011-10-26T02:31:37Z + +[Term] +id: GO:0038036 +name: sphingosine-1-phosphate receptor activity +namespace: molecular_function +def: "Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein." [GOC:bf, PMID:12728273, Wikipedia:S1PR1] +synonym: "S1P receptor activity" EXACT [Wikipedia:Sphingosine_1-phosphate] +is_a: GO:0045125 ! bioactive lipid receptor activity +relationship: part_of GO:0003376 ! sphingosine-1-phosphate receptor signaling pathway +created_by: bf +creation_date: 2011-10-28T03:46:54Z + +[Term] +id: GO:0038037 +name: G protein-coupled receptor dimeric complex +namespace: cellular_component +def: "A protein complex that contains two G protein-coupled receptors." [GOC:al, GOC:bf, PMID:10713101] +synonym: "G-protein coupled receptor dimer" EXACT [GOC:bf] +synonym: "G-protein coupled receptor dimeric complex" EXACT [] +synonym: "GPCR dimer" EXACT [GOC:bf] +is_a: GO:0097648 ! G protein-coupled receptor complex +created_by: bf +creation_date: 2011-11-02T04:42:44Z + +[Term] +id: GO:0038038 +name: G protein-coupled receptor homodimeric complex +namespace: cellular_component +def: "A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor." [GOC:al, GOC:bf, PMID:10713101, PMID:16670762] +synonym: "G-protein coupled receptor homodimer" EXACT [GOC:bf] +synonym: "G-protein coupled receptor homodimeric complex" EXACT [] +synonym: "GPCR homodimer" EXACT [GOC:bf] +is_a: GO:0038037 ! G protein-coupled receptor dimeric complex +created_by: bf +creation_date: 2011-11-02T04:43:53Z + +[Term] +id: GO:0038039 +name: G protein-coupled receptor heterodimeric complex +namespace: cellular_component +def: "A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR." [GOC:al, GOC:bf, PMID:16109836, PMID:20150590] +synonym: "G-protein coupled receptor heterodimer" EXACT [GOC:bf] +synonym: "G-protein coupled receptor heterodimeric complex" EXACT [] +synonym: "GPCR heterodimer" EXACT [PMID:20150590] +is_a: GO:0038037 ! G protein-coupled receptor dimeric complex +created_by: bf +creation_date: 2011-11-02T04:44:20Z + +[Term] +id: GO:0038040 +name: obsolete cross-receptor activation within G-protein coupled receptor heterodimer +namespace: biological_process +def: "OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter." [GOC:al, GOC:bf, PMID:21063387] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15823 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2011-11-02T04:50:22Z + +[Term] +id: GO:0038041 +name: cross-receptor inhibition within G protein-coupled receptor heterodimer +namespace: biological_process +def: "Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit." [GOC:al, GOC:bf, PMID:15979374] +synonym: "cross-receptor inhibition within G-protein coupled receptor heterodimer" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:2000272 ! negative regulation of signaling receptor activity +created_by: bf +creation_date: 2011-11-02T04:52:24Z + +[Term] +id: GO:0038043 +name: interleukin-5-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:pg, GOC:signaling, PR:000001392] +synonym: "IL-5-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-5-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2011-11-03T04:18:21Z + +[Term] +id: GO:0038044 +name: transforming growth factor-beta secretion +namespace: biological_process +def: "The regulated release of transforming growth factor-beta (TGF-beta) from a cell into the extracellular region. TGF-beta is mostly secreted as a large latent TGF-beta complex (LLC) containing latency-associated proteins (LAPs) derived from the N-terminal region of the TGF-beta gene product, dimeric TGF-beta and latent TGF-beta binding proteins (LTBPs)." [GOC:bf, GOC:yaf, PMID:2350783, Reactome:R-HSA-177107] +synonym: "TGF-beta secretion" EXACT [PMID:2022183] +synonym: "TGFbeta secretion" EXACT [PMID:16891311] +is_a: GO:0050663 ! cytokine secretion +created_by: bf +creation_date: 2011-11-03T04:23:35Z + +[Term] +id: GO:0038045 +name: large latent transforming growth factor-beta complex +namespace: cellular_component +def: "A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors." [GOC:bf, PMID:2350783, PMID:8680476, PMID:9805445, Reactome:R-HSA-177107] +synonym: "large latent complex" EXACT [Reactome:R-HSA-177107] +synonym: "LLC" EXACT [Reactome:R-HSA-177107] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2011-11-03T04:29:49Z + +[Term] +id: GO:0038046 +name: enkephalin receptor activity +namespace: molecular_function +def: "Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body." [GOC:bf, Wikipedia:Enkephalin] +synonym: "delta-opioid receptor activity" RELATED [GOC:bf] +is_a: GO:0004985 ! opioid receptor activity +created_by: bf +creation_date: 2011-11-14T01:30:14Z + +[Term] +id: GO:0038047 +name: morphine receptor activity +namespace: molecular_function +def: "Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein." [GOC:bf] +synonym: "mu-opioid receptor activity" RELATED [GOC:bf] +is_a: GO:0004985 ! opioid receptor activity +relationship: part_of GO:0071315 ! cellular response to morphine +created_by: bf +creation_date: 2011-11-14T01:35:18Z + +[Term] +id: GO:0038048 +name: dynorphin receptor activity +namespace: molecular_function +def: "Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin." [GOC:bf, Wikipedia:Dynorphin] +synonym: "kappa-opioid receptor activity" RELATED [GOC:bf] +is_a: GO:0004985 ! opioid receptor activity +created_by: bf +creation_date: 2011-11-14T01:48:02Z + +[Term] +id: GO:0038053 +name: obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements." [GOC:signaling, PMID:17615392] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "estrogen nuclear receptor activity" BROAD [GOC:bf] +synonym: "estrogen-activated RNA polymerase II transcription factor binding transcription factor activity" EXACT [] +is_obsolete: true +created_by: bf +creation_date: 2011-11-29T02:42:22Z + +[Term] +id: GO:0038054 +name: G protein-coupled estrogen receptor activity +namespace: molecular_function +def: "Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:signaling, PMID:17379646, PMID:20960099] +synonym: "G-protein coupled estrogen receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0030284 ! estrogen receptor activity +created_by: bf +creation_date: 2011-11-29T04:29:42Z + +[Term] +id: GO:0038055 +name: BMP secretion +namespace: biological_process +def: "The controlled release of a member of the BMP family of proteins from a cell." [GOC:sart, PR:000000034] +synonym: "BMP protein secretion" EXACT [GOC:bf] +synonym: "bone morphogenetic protein secretion" EXACT [GOC:bf] +is_a: GO:0009306 ! protein secretion +is_a: GO:0023061 ! signal release +created_by: bf +creation_date: 2011-12-14T02:31:39Z + +[Term] +id: GO:0038056 +name: negative regulation of BMP signaling pathway by negative regulation of BMP secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell." [GOC:bf, GOC:sart, PMID:21750037] +synonym: "negative regulation of BMP signaling pathway by negative regulation of bone morphogenetic protein secretion" EXACT [GOC:bf] +synonym: "negative regulation of BMP signalling pathway by negative regulation of BMP secretion" EXACT [GOC:bf] +is_a: GO:0030514 ! negative regulation of BMP signaling pathway +is_a: GO:2001285 ! negative regulation of BMP secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030509 ! BMP signaling pathway +intersection_of: negatively_regulates GO:0038055 ! BMP secretion +created_by: bf +creation_date: 2011-12-19T10:55:47Z + +[Term] +id: GO:0038057 +name: TNFSF11 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family." [GOC:cjm, PR:000002107] +synonym: "CD254 binding" EXACT [GOC:sl, PR:000002107] +synonym: "ODF binding" EXACT [GOC:sl, PR:000002107] +synonym: "OPGL binding" EXACT [GOC:sl, PR:000002107] +synonym: "osteoclast differentiation factor binding" EXACT [GOC:sl, PR:000002107] +synonym: "osteoprotegerin ligand binding" EXACT [GOC:sl, PR:000002107] +synonym: "RANKL binding" EXACT [GOC:sl, PR:000002107] +synonym: "receptor activator of nuclear factor kappa-B ligand binding" EXACT [GOC:sl, PR:000002107] +synonym: "TNF-related activation-induced cytokine binding" EXACT [GOC:sl, PR:000002107] +synonym: "TRANCE binding" EXACT [GOC:sl, PR:000002107] +synonym: "tumor necrosis factor (ligand) superfamily member 11 binding" EXACT [GOC:bf] +synonym: "tumor necrosis factor ligand superfamily member 11 binding" EXACT [PR:000002107] +synonym: "tumor necrosis factor superfamily member 11 binding" EXACT [GOC:bf] +is_a: GO:0043120 ! tumor necrosis factor binding +created_by: bf +creation_date: 2012-01-04T03:25:59Z + +[Term] +id: GO:0038058 +name: TNFSF11 receptor activity +namespace: molecular_function +def: "Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function." [GOC:bf, GOC:cjm, PR:000002107] +synonym: "RANKL receptor activity" EXACT [PR:000002107, Wikipedia:RANKL] +synonym: "tumor necrosis factor ligand superfamily member 11 receptor activity" EXACT [PR:000002107, Wikipedia:RANKL] +is_a: GO:0005031 ! tumor necrosis factor-activated receptor activity +relationship: has_part GO:0038057 ! TNFSF11 binding +relationship: part_of GO:0071847 ! TNFSF11-mediated signaling pathway +created_by: bf +creation_date: 2012-01-04T03:31:54Z + +[Term] +id: GO:0038059 +name: IKKalpha-IKKalpha complex +namespace: cellular_component +def: "A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits." [GOC:bf, PMID:18626576, PMID:21173796] +synonym: "IkappaB kinase alpha homodimer" EXACT [GOC:bf] +synonym: "IkappaB kinase-alpha homodimer" EXACT [PMID:21173796] +synonym: "IKKalpha homodimer" EXACT [GOC:bf] +synonym: "IKKalpha homodimeric complex" EXACT [GOC:bf] +synonym: "IKKalpha-IKKalpha protein complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2012-01-10T09:29:53Z + +[Term] +id: GO:0038060 +name: nitric oxide-cGMP-mediated signaling pathway +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP." [GOC:signaling, PMID:21549190, PMID:22019632] +synonym: "canonical nitric oxide signaling" EXACT [GOC:bf] +synonym: "classical nitric oxide signaling" EXACT [PMID:21549190] +synonym: "nitric oxide-cGMP-mediated signalling pathway" EXACT [GOC:mah] +synonym: "NO-cGMP signaling pathway" EXACT [PMID:22019632] +is_a: GO:0007263 ! nitric oxide mediated signal transduction +is_a: GO:0019934 ! cGMP-mediated signaling +created_by: bf +creation_date: 2012-01-10T05:32:39Z + +[Term] +id: GO:0038061 +name: NIK/NF-kappaB signaling +namespace: biological_process +def: "The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52)." [GOC:bf, GOC:mg2, GOC:signaling, GOC:vs, PMID:11239468, PMID:15140882] +synonym: "NIK/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "NIK/NF-kappaB signal transduction" EXACT [GOC:signaling] +synonym: "non-canonical NF-KB signaling" BROAD [PMID:21173796] +synonym: "noncanonical NF-kappaB signaling" BROAD [PMID:20501935] +synonym: "noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [PMID:20501935] +synonym: "p52-dependent NF-kappaB signaling" NARROW [PMID:18292232] +is_a: GO:0035556 ! intracellular signal transduction +relationship: has_part GO:0051092 ! positive regulation of NF-kappaB transcription factor activity +created_by: bf +creation_date: 2012-01-16T05:44:46Z + +[Term] +id: GO:0038062 +name: protein tyrosine kinase collagen receptor activity +namespace: molecular_function +def: "Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [GOC:bf, GOC:uh, PMID:16626936, PMID:21568710] +synonym: "collagen RTK activity" EXACT [PMID:21568710] +synonym: "discoidin domain receptor" RELATED [PMID:16626936] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +is_a: GO:0038064 ! collagen receptor activity +relationship: part_of GO:0038063 ! collagen-activated tyrosine kinase receptor signaling pathway +created_by: bf +creation_date: 2012-01-18T01:38:40Z + +[Term] +id: GO:0038063 +name: collagen-activated tyrosine kinase receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:uh, PMID:15888913, PMID:16626936] +synonym: "collagen-activated RTK signaling pathway" EXACT [PMID:21568710] +synonym: "collagen-activated tyrosine kinase receptor signalling pathway" EXACT [GOC:mah] +synonym: "DDR signaling pathway" NARROW [PMID:16626936] +synonym: "discoidin domain receptor signaling pathway" NARROW [PMID:16626936] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +is_a: GO:0038065 ! collagen-activated signaling pathway +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-01-18T01:43:20Z + +[Term] +id: GO:0038064 +name: collagen receptor activity +namespace: molecular_function +def: "Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:uh, PMID:21568710] +synonym: "transmembrane collagen receptor activity" EXACT [PMID:21568710] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0005518 ! collagen binding +relationship: part_of GO:0038065 ! collagen-activated signaling pathway +created_by: bf +creation_date: 2012-01-18T01:52:42Z + +[Term] +id: GO:0038065 +name: collagen-activated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:uh, PMID:21568710] +synonym: "collagen-activated signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-01-18T01:57:37Z + +[Term] +id: GO:0038066 +name: p38MAPK cascade +namespace: biological_process +def: "An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:signaling, PMID:20811974] +synonym: "p38 cascade" EXACT [PMID:20811974] +synonym: "p38 MAPK cascade" EXACT [GOC:bf] +is_a: GO:0051403 ! stress-activated MAPK cascade +created_by: bf +creation_date: 2012-01-25T11:51:24Z + +[Term] +id: GO:0038067 +name: obsolete MAP kinase activity involved in cell wall organization or biogenesis +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase activity involved in cell wall biogenesis" NARROW [] +synonym: "MAP kinase activity involved in cell wall integrity" RELATED [GOC:vw] +synonym: "MAPK activity involved in cell wall biogenesis" NARROW [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-25T03:29:04Z + +[Term] +id: GO:0038068 +name: obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis +namespace: molecular_function +def: "OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase kinase activity involved in cell wall biogenesis" NARROW [GOC:vw] +synonym: "MAP2K activity involved in cell wall integrity" EXACT [GOC:bf] +synonym: "MAPKK activity involved in cell wall integrity" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-25T03:34:10Z + +[Term] +id: GO:0038069 +name: obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "Mpk1 phosphatase activity" NARROW [PMID:10523653] +synonym: "Slt2 phosphatase activity" NARROW [PMID:10523653] +is_obsolete: true +created_by: bf +creation_date: 2012-01-25T03:38:58Z + +[Term] +id: GO:0038070 +name: obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase kinase kinase activity involved in cell wall biogenesis" EXACT [GOC:vw] +synonym: "MAP3K activity involved in cell wall integrity" EXACT [GOC:bf] +synonym: "MAPKKK activity involved in cell wall integrity" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-25T03:43:46Z + +[Term] +id: GO:0038071 +name: obsolete MAP kinase activity involved in conjugation with cellular fusion +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAPK activity involved in conjugation with cellular fusion" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:31:57Z + +[Term] +id: GO:0038072 +name: obsolete MAP kinase kinase activity involved in conjugation with cellular fusion +namespace: molecular_function +def: "OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP2K activity involved in conjugation with cellular fusion" EXACT [GOC:signaling] +synonym: "MAPKK activity involved in conjugation with cellular fusion" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:31:57Z + +[Term] +id: GO:0038073 +name: obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP3K activity involved in conjugation with cellular fusion" EXACT [GOC:signaling] +synonym: "MAPKKK activity involved in conjugation with cellular fusion" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:31:57Z + +[Term] +id: GO:0038074 +name: obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAPK phosphatase activity involved in regulation of conjugation with cellular fusion" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:31:57Z + +[Term] +id: GO:0038075 +name: obsolete MAP kinase activity involved in innate immune response +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response." [GOC:signaling] +comment: This term was obsoleted because it should be represented as a GO-CAM model. +synonym: "MAPK activity involved in innate immune response" EXACT [GOC:signaling] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18000 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:35:52Z + +[Term] +id: GO:0038076 +name: obsolete MAP kinase kinase activity involved in innate immune response +namespace: molecular_function +def: "OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP2K activity involved in innate immune response" EXACT [GOC:signaling] +synonym: "MAPKK activity involved in innate immune response" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:35:52Z + +[Term] +id: GO:0038077 +name: obsolete MAP kinase kinase kinase activity involved in innate immune response +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP3K activity involved in innate immune response" EXACT [GOC:signaling] +synonym: "MAPKKK activity involved in innate immune response" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:35:52Z + +[Term] +id: GO:0038078 +name: MAP kinase phosphatase activity involved in regulation of innate immune response +namespace: molecular_function +def: "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response." [GOC:signaling] +synonym: "MAPK phosphatase activity involved in regulation of innate immune response" EXACT [GOC:bf] +is_a: GO:0033549 ! MAP kinase phosphatase activity +intersection_of: GO:0033549 ! MAP kinase phosphatase activity +intersection_of: part_of GO:0045088 ! regulation of innate immune response +relationship: part_of GO:0035423 ! inactivation of MAPK activity involved in innate immune response +relationship: part_of GO:0045088 ! regulation of innate immune response +created_by: bf +creation_date: 2012-01-26T02:35:52Z + +[Term] +id: GO:0038079 +name: obsolete MAP kinase activity involved in osmosensory signaling pathway +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "MAPK activity involved in osmosensory signaling pathway" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:41:31Z + +[Term] +id: GO:0038080 +name: obsolete MAP kinase kinase activity involved in osmosensory signaling pathway +namespace: molecular_function +def: "OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase kinase activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "MAP2K activity involved in osmosensory signaling pathway" EXACT [GOC:signaling] +synonym: "MAPKK activity involved in osmosensory signaling pathway" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:41:31Z + +[Term] +id: GO:0038081 +name: obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "MAP kinase kinase kinase activity involved in osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "MAP3K activity involved in osmosensory signaling pathway" EXACT [GOC:signaling] +synonym: "MAPKKK activity involved in osmosensory signaling pathway" EXACT [GOC:signaling] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:41:31Z + +[Term] +id: GO:0038082 +name: obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway." [GOC:signaling] +comment: This term has been obsoleted because it represents a GO-CAM model rather than a single GO term. +synonym: "Hog1 phosphatase activity" NARROW [PMID:20880736] +synonym: "MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway" EXACT [GOC:mah] +synonym: "MAPK phosphatase activity involved in regulation of osmosensory signaling pathway" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-26T02:41:31Z + +[Term] +id: GO:0038083 +name: peptidyl-tyrosine autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein." [PMID:10037737, PMID:10068444, PMID:10940390] +synonym: "receptor tyrosine kinase autophosphorylation" NARROW [PMID:20432069] +synonym: "RTK autophosphorylation" NARROW [PMID:20432069] +synonym: "tyrosine autophosphorylation" EXACT [PMID:16431914] +is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation +is_a: GO:0046777 ! protein autophosphorylation +created_by: bf +creation_date: 2012-02-01T02:14:18Z + +[Term] +id: GO:0038084 +name: vascular endothelial growth factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:17470632, PR:000003096, PR:000007520, PR:000017284, PR:000017285] +comment: In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'. +synonym: "vascular endothelial growth factor signalling pathway" EXACT [GOC:bf] +synonym: "VEGF signaling" EXACT [GOC:bf] +synonym: "VEGF-activated signaling pathway" EXACT [GOC:bf] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +relationship: part_of GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +created_by: bf +creation_date: 2012-02-01T02:27:32Z + +[Term] +id: GO:0038085 +name: vascular endothelial growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a vascular endothelial growth factor." [PMID:17470632, PR:000003096, PR:000007520, PR:000017284, PR:000017285] +synonym: "VEGF binding" EXACT [GOC:bf] +is_a: GO:0019838 ! growth factor binding +created_by: bf +creation_date: 2012-02-01T02:36:36Z + +[Term] +id: GO:0038086 +name: VEGF-activated platelet-derived growth factor receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:17470632] +synonym: "vascular endothelial growth factor-activated platelet-derived growth factor receptor signaling pathway" EXACT [GOC:bf] +synonym: "VEGF-A/PDGFR signaling" NARROW [PMID:17470632] +synonym: "VEGF-activated PDGFR signalling pathway" EXACT [GOC:bf] +synonym: "VEGF-activated platelet-derived growth factor receptor signalling pathway" EXACT [GOC:bf] +synonym: "VEGF/PDGFR signaling pathway" EXACT [PMID:17470632] +is_a: GO:0038084 ! vascular endothelial growth factor signaling pathway +is_a: GO:0048008 ! platelet-derived growth factor receptor signaling pathway +relationship: has_part GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2012-02-01T03:05:43Z + +[Term] +id: GO:0038087 +name: VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:17470632] +synonym: "vascular endothelial growth factor-activated platelet-derived growth factor receptor-alpha signaling pathway" EXACT [GOC:bf] +synonym: "VEGF-A/PDGFRalpha signaling" NARROW [PMID:17470632] +synonym: "VEGF-activated PDGFRalpha signalling pathway" EXACT [GOC:bf] +synonym: "VEGF-activated platelet-derived growth factor receptor-alpha signalling pathway" EXACT [GOC:bf] +synonym: "VEGF/PDGFRalpha signaling pathway" EXACT [PMID:17470632] +is_a: GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +is_a: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +created_by: bf +creation_date: 2012-02-01T03:08:13Z + +[Term] +id: GO:0038088 +name: VEGF-activated platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:17470632] +synonym: "vascular endothelial growth factor-activated platelet-derived growth factor receptor-beta signaling pathway" EXACT [GOC:bf] +synonym: "VEGF-A/PDGFRbeta signaling" NARROW [PMID:17470632] +synonym: "VEGF-activated PDGFRbeta signalling pathway" EXACT [GOC:bf] +synonym: "VEGF-activated platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:bf] +synonym: "VEGF/PDGFRbeta signaling pathway" EXACT [PMID:17470632] +is_a: GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +is_a: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +created_by: bf +creation_date: 2012-02-01T03:10:16Z + +[Term] +id: GO:0038089 +name: positive regulation of cell migration by vascular endothelial growth factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another." [GOC:bf, GOC:signaling, PR:000003096, PR:000017284, PR:000017285] +synonym: "positive regulation of cell migration by vascular endothelial growth factor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of cell migration by VEGF signaling pathway" EXACT [GOC:bf] +synonym: "VEGF-A-induced cell migration" NARROW [PMID:17470632] +synonym: "VEGF-induced cell migration" EXACT [GOC:bf] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0038084 ! vascular endothelial growth factor signaling pathway +intersection_of: GO:0038084 ! vascular endothelial growth factor signaling pathway +intersection_of: positively_regulates GO:0016477 ! cell migration +created_by: bf +creation_date: 2012-02-02T03:40:13Z + +[Term] +id: GO:0038090 +name: positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another." [GOC:bf, GOC:signaling, PMID:17470632] +synonym: "positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of cell migration by VEGF/PDGFR signaling pathway" EXACT [PMID:17470632] +synonym: "VEGF/PDGFR-induced cell migration" EXACT [PMID:17470632] +is_a: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +is_a: GO:0038089 ! positive regulation of cell migration by vascular endothelial growth factor signaling pathway +intersection_of: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +intersection_of: positively_regulates GO:0016477 ! cell migration +created_by: bf +creation_date: 2012-02-02T03:41:23Z + +[Term] +id: GO:0038091 +name: positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation." [GOC:signaling, PMID:17470632] +synonym: "positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of cell proliferation by VEGF/PDGFR signaling pathway" EXACT [GOC:bf] +synonym: "VEGF-A-induced cell proliferation" NARROW [PMID:17470632] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +intersection_of: GO:0038086 ! VEGF-activated platelet-derived growth factor receptor signaling pathway +intersection_of: positively_regulates GO:0008283 ! cell population proliferation +created_by: bf +creation_date: 2012-02-02T03:45:49Z + +[Term] +id: GO:0038092 +name: nodal signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:vk, PMID:17287255] +synonym: "nodal signaling" EXACT [GOC:bf] +synonym: "nodal signalling pathway" EXACT [GOC:mah] +is_a: GO:0032924 ! activin receptor signaling pathway +created_by: bf +creation_date: 2012-02-16T02:44:02Z + +[Term] +id: GO:0038093 +name: Fc receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:phg, Wikipedia:Fc_receptor] +synonym: "Fc receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0002768 ! immune response-regulating cell surface receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-02-16T05:11:30Z + +[Term] +id: GO:0038094 +name: Fc-gamma receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:phg, PMID:11244038] +synonym: "Fc-gamma receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0038093 ! Fc receptor signaling pathway +created_by: bf +creation_date: 2012-02-16T05:22:46Z + +[Term] +id: GO:0038095 +name: Fc-epsilon receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:phg, PMID:12413516, PMID:15048725] +synonym: "Fc-epsilon receptor signalling pathway" EXACT [GOC:bf] +is_a: GO:0038093 ! Fc receptor signaling pathway +created_by: bf +creation_date: 2012-02-16T05:23:51Z + +[Term] +id: GO:0038096 +name: Fc-gamma receptor signaling pathway involved in phagocytosis +namespace: biological_process +def: "An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes." [GOC:phg, PMID:12488490, PMID:15466916] +synonym: "Fc gamma receptor-dependent phagocytosis" EXACT [PMID:18832707] +synonym: "Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:bf] +synonym: "Fcgamma receptor-mediated phagocytosis" EXACT [PMID:15466916] +synonym: "IgG-mediated phagocytosis" EXACT [PMID:1248849] +is_a: GO:0002431 ! Fc receptor mediated stimulatory signaling pathway +is_a: GO:0002433 ! immune response-regulating cell surface receptor signaling pathway involved in phagocytosis +is_a: GO:0038094 ! Fc-gamma receptor signaling pathway +intersection_of: GO:0038094 ! Fc-gamma receptor signaling pathway +intersection_of: part_of GO:0006909 ! phagocytosis +created_by: bf +creation_date: 2012-02-16T05:26:25Z + +[Term] +id: GO:0038097 +name: positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway +namespace: biological_process +def: "An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors." [GOC:phg, PMID:12413516] +synonym: "Fc epsilon RI-dependent mast cell activation" EXACT [PMID:18377769] +synonym: "Fc epsilon RI-mediated mast cell activation" EXACT [PMID:17336609] +synonym: "positive regulation of mast cell activation by Fc-epsilon receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0002431 ! Fc receptor mediated stimulatory signaling pathway +is_a: GO:0033005 ! positive regulation of mast cell activation +is_a: GO:0038095 ! Fc-epsilon receptor signaling pathway +intersection_of: GO:0038095 ! Fc-epsilon receptor signaling pathway +intersection_of: positively_regulates GO:0045576 ! mast cell activation +created_by: bf +creation_date: 2012-02-16T05:30:09Z + +[Term] +id: GO:0038098 +name: sequestering of BMP from receptor via BMP binding +namespace: biological_process +def: "Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor." [GOC:bf, GOC:signaling, PMID:19855014] +synonym: "extracellular sequestering of BMP" BROAD [GOC:bf] +synonym: "extracellular sequestering of bone morphogenetic protein" BROAD [GOC:bf] +is_a: GO:0030514 ! negative regulation of BMP signaling pathway +is_a: GO:0035581 ! sequestering of extracellular ligand from receptor +created_by: bf +creation_date: 2012-02-22T11:28:54Z + +[Term] +id: GO:0038099 +name: nodal receptor complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals)." [GOC:bf, GOC:signaling, PMID:15062104] +synonym: "ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:bf] +synonym: "nodal receptor complex formation" EXACT [GOC:bf] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0038092 ! nodal signaling pathway +created_by: bf +creation_date: 2012-02-17T11:16:40Z + +[Term] +id: GO:0038100 +name: nodal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nodal protein, a member of the transforming growth factor-beta superfamily." [GOC:bf, PMID:20629020, PR:000000105] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-02-17T11:19:08Z + +[Term] +id: GO:0038101 +name: sequestering of nodal from receptor via nodal binding +namespace: biological_process +def: "Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor." [GOC:signaling, PMID:14570583, PMID:15062104] +synonym: "binding to and sequestering nodal" EXACT [GOC:bf] +synonym: "extracellular regulation of nodal" BROAD [GOC:bf] +synonym: "nodal antagonist activity" BROAD [PMID:14570583] +is_a: GO:0035581 ! sequestering of extracellular ligand from receptor +relationship: has_part GO:0038100 ! nodal binding +relationship: part_of GO:1900108 ! negative regulation of nodal signaling pathway +created_by: bf +creation_date: 2012-02-17T11:21:22Z + +[Term] +id: GO:0038102 +name: activin receptor antagonist activity +namespace: molecular_function +def: "Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor." [GOC:signaling, PMID:15062104] +comment: This term refers to inhibition of a member of the activin receptor family; activin receptors bind to multiple ligands including activin and nodal. +is_a: GO:0048019 ! receptor antagonist activity +relationship: part_of GO:0032926 ! negative regulation of activin receptor signaling pathway +created_by: bf +creation_date: 2012-02-17T11:28:59Z + +[Term] +id: GO:0038103 +name: activin receptor antagonist activity involved in negative regulation of nodal signaling pathway +namespace: molecular_function +def: "Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor." [GOC:signaling, PMID:15062104] +synonym: "activin receptor antagonist activity involved in negative regulation of nodal signalling pathway" EXACT [GOC:mah] +synonym: "nodal antagonist activity" EXACT [GOC:bf] +is_a: GO:0038102 ! activin receptor antagonist activity +intersection_of: GO:0038102 ! activin receptor antagonist activity +intersection_of: part_of GO:1900108 ! negative regulation of nodal signaling pathway +relationship: part_of GO:1900108 ! negative regulation of nodal signaling pathway +created_by: bf +creation_date: 2012-02-17T11:30:21Z + +[Term] +id: GO:0038104 +name: nodal receptor complex +namespace: cellular_component +def: "A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell." [GOC:bf, GOC:signaling, PMID:11024047, PMID:15062104] +comment: Nodal signals through activin receptors but (unlike activin) also requires EGF-CFC coreceptors (such as Cripto or Cryptic in mammals) to signal. This term is intended for receptor/co-receptor components and not a nodal-receptor complex. +synonym: "ActRIIB.ALK4.EGF-CFC complex" NARROW [GOC:bf] +is_a: GO:0043235 ! receptor complex +created_by: bf +creation_date: 2012-02-17T11:12:21Z + +[Term] +id: GO:0038105 +name: sequestering of TGFbeta from receptor via TGFbeta binding +namespace: biological_process +def: "Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor." [GOC:bf, GOC:signaling, PMID:19855014] +comment: This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'. +synonym: "extracellular sequestering of TGFbeta" BROAD [GOC:bf] +synonym: "extracellular sequestering of transforming growth factor-beta" BROAD [GOC:bf] +is_a: GO:0035581 ! sequestering of extracellular ligand from receptor +created_by: bf +creation_date: 2012-02-22T11:35:58Z + +[Term] +id: GO:0038106 +name: choriogonadotropin hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit." [GOC:BHF, GOC:rl, Wikipedia:Human_chorionic_gonadotropin] +synonym: "chorionic gonadotrophin binding" EXACT [Wikilpedia:Human_chorionic_gonadotropin] +synonym: "chorionic gonadotropin binding" EXACT [Wikipedia:Human_chorionic_gonadotropin] +is_a: GO:0042562 ! hormone binding +created_by: bf +creation_date: 2012-03-08T03:58:40Z + +[Term] +id: GO:0038107 +name: nodal signaling pathway involved in determination of left/right asymmetry +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves." [GOC:BHF, GOC:vk, PMID:12857784, PMID:17287255, PMID:20413706] +synonym: "nodal signalling pathway involved in determination of left/right asymmetry" EXACT [GOC:mah] +synonym: "regulation of transcription from RNA polymerase II promoter by nodal signaling pathway, involved in determination of left/right symmetry" EXACT [GOC:bf] +is_a: GO:0038092 ! nodal signaling pathway +is_a: GO:1900094 ! regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry +intersection_of: GO:0038092 ! nodal signaling pathway +intersection_of: part_of GO:0007368 ! determination of left/right symmetry +created_by: bf +creation_date: 2012-02-29T10:18:59Z + +[Term] +id: GO:0038108 +name: negative regulation of appetite by leptin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food." [GOC:BHF, GOC:vk, PMID:19150989] +synonym: "inhibition of appetite by leptin signaling" EXACT [GOC:bf] +synonym: "negative regulation of appetite by leptin-mediated signalling pathway" EXACT [GOC:mah] +synonym: "reduction of appetite by leptin-mediated signaling" EXACT [GOC:bf] +synonym: "suppression of appetite by leptin-mediated signaling pathway" EXACT [GOC:bf] +is_a: GO:0032099 ! negative regulation of appetite +is_a: GO:0033210 ! leptin-mediated signaling pathway +created_by: bf +creation_date: 2012-03-09T11:14:36Z + +[Term] +id: GO:0038109 +name: Kit signaling pathway +namespace: biological_process +def: "A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell." [GOC:nhn, GOC:signaling, PMID:16129412] +synonym: "Kit signalling pathway" EXACT [GOC:mah] +synonym: "SCF signaling pathway" EXACT [PMID:18787413] +synonym: "stem cell factor receptor signaling pathway" EXACT [PMID:16129412] +synonym: "stem cell factor signaling pathway" EXACT [PMID:16129412] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0036216 ! cellular response to stem cell factor stimulus +created_by: bf +creation_date: 2012-03-22T10:09:48Z + +[Term] +id: GO:0038110 +name: interleukin-2-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-2-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-2-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071352 ! cellular response to interleukin-2 +created_by: bf +creation_date: 2012-03-22T10:18:29Z + +[Term] +id: GO:0038111 +name: interleukin-7-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-7-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-7-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0098761 ! cellular response to interleukin-7 +created_by: bf +creation_date: 2012-03-22T10:19:27Z + +[Term] +id: GO:0038112 +name: interleukin-8-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-8-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-8-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0098759 ! cellular response to interleukin-8 +created_by: bf +creation_date: 2012-03-22T10:19:59Z + +[Term] +id: GO:0038113 +name: interleukin-9-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-9-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-9-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071355 ! cellular response to interleukin-9 +created_by: bf +creation_date: 2012-03-22T10:20:33Z + +[Term] +id: GO:0038114 +name: interleukin-21-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-21-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-21-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0098757 ! cellular response to interleukin-21 +created_by: bf +creation_date: 2012-03-22T10:21:01Z + +[Term] +id: GO:0038115 +name: chemokine (C-C motif) ligand 19 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:15059845, PR:000001991] +comment: The C-C chemokine CCL19 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL19-activated CCR7 signaling pathway ; GO:0038119'. +synonym: "C-C chemokine receptor type 7 signaling pathway" RELATED [PMID:15059845, PR:000001203] +synonym: "CCL19-mediated signaling pathway" EXACT [PMID:15059845] +synonym: "chemokine (C-C motif) ligand 19 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-03-22T11:28:32Z + +[Term] +id: GO:0038116 +name: chemokine (C-C motif) ligand 21 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:15059845, PR:000001993] +comment: The C-C chemokine CCL21 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL21-activated CCR7 signaling pathway ; GO:0038120'. +synonym: "C-C chemokine receptor type 7 signaling pathway" RELATED [PMID:15059845, PR:000001203] +synonym: "CCL21-mediated signaling pathway" EXACT [PMID:15059845] +synonym: "chemokine (C-C motif) ligand 21 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-03-22T11:30:47Z + +[Term] +id: GO:0038117 +name: C-C motif chemokine 19 receptor activity +namespace: molecular_function +def: "Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:signaling, PMID:15059845, PR:000001991] +synonym: "CCL19 receptor activity" RELATED [PMID:15059845] +is_a: GO:0016493 ! C-C chemokine receptor activity +relationship: has_part GO:0035757 ! chemokine (C-C motif) ligand 19 binding +relationship: part_of GO:0038115 ! chemokine (C-C motif) ligand 19 signaling pathway +created_by: bf +creation_date: 2012-03-22T11:59:10Z + +[Term] +id: GO:0038118 +name: C-C chemokine receptor CCR7 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:15059845, PMID:15778365, PR:000001203] +comment: This term was created to show the binding of cytokines to multiple receptor types, and vice-versa. Known agonists of chemokine receptor type 7 (CCR7) are C-C chemokines CCL19 and CCL21. Consider instead annotating to one of the child terms 'CCL19-activated CCR7 signaling pathway ; GO:0038119' and/or 'CCL21-activated CCR7 signaling pathway ; GO:0038120'. +synonym: "C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:mah] +synonym: "CCR7 signaling pathway" RELATED [PR:000001203] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-03-22T11:43:57Z + +[Term] +id: GO:0038119 +name: CCL19-activated CCR7 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:15059845, PR:000001203] +synonym: "CCL19-activated CCR7 signalling pathway" EXACT [GOC:mah] +is_a: GO:0038115 ! chemokine (C-C motif) ligand 19 signaling pathway +is_a: GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +created_by: bf +creation_date: 2012-03-22T11:47:24Z + +[Term] +id: GO:0038120 +name: CCL21-activated CCR7 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:15059845, PR:000001203] +synonym: "CCL21-activated CCR7 signalling pathway" EXACT [GOC:mah] +is_a: GO:0038116 ! chemokine (C-C motif) ligand 21 signaling pathway +is_a: GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +created_by: bf +creation_date: 2012-03-22T11:47:24Z + +[Term] +id: GO:0038121 +name: C-C motif chemokine 21 receptor activity +namespace: molecular_function +def: "Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:signaling, PMID:15059845, PR:000001993] +synonym: "CCL21 receptor activity" RELATED [PMID:15059845, PR:000001993] +is_a: GO:0016493 ! C-C chemokine receptor activity +relationship: has_part GO:0035758 ! chemokine (C-C motif) ligand 21 binding +relationship: part_of GO:0038116 ! chemokine (C-C motif) ligand 21 signaling pathway +created_by: bf +creation_date: 2012-03-22T01:28:06Z + +[Term] +id: GO:0038122 +name: C-C motif chemokine 5 receptor activity +namespace: molecular_function +def: "Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:signaling, PR:000002094] +synonym: "CCL5 receptor activity" EXACT [PR:000002094] +synonym: "RANTES receptor activity" EXACT [GOC:bf] +synonym: "small inducible cytokine A5 receptor activity" EXACT [PR:000002094] +is_a: GO:0016493 ! C-C chemokine receptor activity +relationship: has_part GO:0071791 ! chemokine (C-C motif) ligand 5 binding +relationship: part_of GO:0035689 ! chemokine (C-C motif) ligand 5 signaling pathway +created_by: bf +creation_date: 2012-03-22T01:36:00Z + +[Term] +id: GO:0038123 +name: toll-like receptor TLR1:TLR2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:17318230] +synonym: "TLR2:TLR1 signaling pathway" EXACT [GOC:bf] +synonym: "toll-like receptor TLR1:TLR2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0002224 ! toll-like receptor signaling pathway +created_by: bf +creation_date: 2012-03-23T10:20:13Z + +[Term] +id: GO:0038124 +name: toll-like receptor TLR6:TLR2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:17318230] +synonym: "TLR2:TLR6 signaling pathway" EXACT [GOC:bf] +synonym: "toll-like receptor TLR6:TLR2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0002224 ! toll-like receptor signaling pathway +created_by: bf +creation_date: 2012-03-23T10:29:09Z + +[Term] +id: GO:0038127 +name: ERBB signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, PMID:16460914, PR:000001812, Wikipedia:ErbB] +synonym: "EGF receptor family signaling pathway" EXACT [PMID:11597398] +synonym: "EGFR family signaling pathway" RELATED [PMID:11597398] +synonym: "ErbB signaling" EXACT [PMID:20933094, Wikipedia:ErbB] +synonym: "ERBB signalling pathway" EXACT [GOC:mah] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +created_by: bf +creation_date: 2012-03-30T09:23:01Z + +[Term] +id: GO:0038128 +name: ERBB2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair." [GOC:jc, PMID:16460914, PR:000002082, Reactome:R-HSA-1227986] +synonym: "ERBB2 signalling pathway" EXACT [GOC:mah] +synonym: "HER2 signaling pathway" EXACT [PR:000002082] +synonym: "NEU signaling" EXACT [Reactome:R-HSA-1227986] +synonym: "receptor tyrosine-protein kinase erbB-2 signaling pathway" EXACT [PR:000002082] +is_a: GO:0038127 ! ERBB signaling pathway +created_by: bf +creation_date: 2012-03-30T10:05:12Z + +[Term] +id: GO:0038129 +name: ERBB3 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission." [GOC:jc, PMID:16460914, PR:000007159, Reactome:R-HSA-1247497] +synonym: "ERBB3 signalling pathway" EXACT [GOC:mah] +synonym: "HER3 signaling pathway" EXACT [PR:000007159] +synonym: "receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [PR:000007159] +is_a: GO:0038127 ! ERBB signaling pathway +created_by: bf +creation_date: 2012-03-30T10:42:28Z + +[Term] +id: GO:0038130 +name: ERBB4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, PMID:16460914, PR:000007160, Reactome:R-HSA-1236394] +synonym: "ERBB4 signalling pathway" EXACT [GOC:mah] +synonym: "HER4 signaling pathway" EXACT [PR:000007160] +synonym: "receptor tyrosine-protein kinase erbB-4 signaling pathway" EXACT [PR:000007160] +is_a: GO:0038127 ! ERBB signaling pathway +created_by: bf +creation_date: 2012-03-30T10:44:08Z + +[Term] +id: GO:0038131 +name: neuregulin receptor activity +namespace: molecular_function +def: "Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:signaling, PMID:16460914, PMID:20672328] +comment: Consider also annotating to 'ERBB3 signaling pathway ; GO:0038129' and/or 'ERBB4 signaling pathway ; GO:0038130'. +synonym: "NRG receptor activity" EXACT [PMID:16460914] +synonym: "NRG1 receptor activity" NARROW [PMID:16460914] +synonym: "NRG2 receptor activity" NARROW [PMID:16460914] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0038132 ! neuregulin binding +created_by: bf +creation_date: 2012-03-30T10:47:11Z + +[Term] +id: GO:0038132 +name: neuregulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuregulin, a member of the EGF family of growth factors." [GOC:bf, GOC:signaling] +is_a: GO:0019838 ! growth factor binding +created_by: bf +creation_date: 2012-03-30T10:59:56Z + +[Term] +id: GO:0038133 +name: ERBB2-ERBB3 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589] +synonym: "ERBB2-ERBB3 signalling pathway" EXACT [GOC:mah] +synonym: "HER2-HER3 signaling pathway" EXACT [PR:000002082, PR:000007159] +is_a: GO:0038128 ! ERBB2 signaling pathway +is_a: GO:0038129 ! ERBB3 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:10:44Z + +[Term] +id: GO:0038134 +name: ERBB2-EGFR signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589] +synonym: "EGFR-HER2 signaling pathway" EXACT [PR:000002082, PR:000006933] +synonym: "ERBB2-EGFR signalling pathway" EXACT [GOC:mah] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +is_a: GO:0038128 ! ERBB2 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:16:28Z + +[Term] +id: GO:0038135 +name: ERBB2-ERBB4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589] +synonym: "ERBB2-ERBB4 signalling pathway" EXACT [GOC:mah] +synonym: "HER2-HER4 signaling pathway" EXACT [PR:000002082, PR:000007160] +is_a: GO:0038128 ! ERBB2 signaling pathway +is_a: GO:0038130 ! ERBB4 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:19:52Z + +[Term] +id: GO:0038136 +name: ERBB3-ERBB4 signaling pathway +namespace: biological_process +def: "A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1977958] +synonym: "ERBB3-ERBB4 signalling pathway" EXACT [GOC:mah] +synonym: "HER3-HER4 signaling pathway" EXACT [PR:000007159, PR:000007160] +is_a: GO:0038129 ! ERBB3 signaling pathway +is_a: GO:0038130 ! ERBB4 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:21:19Z + +[Term] +id: GO:0038137 +name: ERBB4-EGFR signaling pathway +namespace: biological_process +def: "A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1977959] +synonym: "ERBB1-ERBB4 signaling pathway" EXACT [PR:000006933, PR:000007160] +synonym: "ERBB4-EGFR signalling pathway" EXACT [GOC:mah] +synonym: "HER1-HER4 signaling pathway" EXACT [PR:000006933, PR:000007160] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +is_a: GO:0038130 ! ERBB4 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:30:30Z + +[Term] +id: GO:0038138 +name: ERBB4-ERBB4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1250220] +synonym: "ERBB4 homodimeric signaling pathway" EXACT [PMID:16460914] +synonym: "ERBB4-ERBB4 signalling pathway" EXACT [GOC:mah] +synonym: "HER4-HER4 signaling pathway" EXACT [PR:000007160] +is_a: GO:0038130 ! ERBB4 signaling pathway +created_by: bf +creation_date: 2012-03-30T11:41:05Z + +[Term] +id: GO:0038139 +name: ERBB4-EGFR complex +namespace: cellular_component +def: "A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1)." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1977956] +synonym: "EGFR-ERBB4 complex" EXACT [GOC:bf] +synonym: "ERBB4:EGFR heterodimer" EXACT [Reactome:R-HSA-1977956] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T01:59:41Z + +[Term] +id: GO:0038140 +name: ERBB4-ERBB3 complex +namespace: cellular_component +def: "A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1977955] +synonym: "ERBB3-ERBB4 complex" EXACT [GOC:bf] +synonym: "ERBB4:ERBB3 heterodimer" EXACT [Reactome:117805.1] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T02:04:16Z + +[Term] +id: GO:0038141 +name: ERBB4-ERBB4 complex +namespace: cellular_component +def: "A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4)." [GOC:signaling, PMID:16460914, Reactome:R-HSA-1250221] +synonym: "ERBB4 homodimer" EXACT [Reactome:R-HSA-1977955] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T02:06:20Z + +[Term] +id: GO:0038142 +name: EGFR:ERBB2 complex +namespace: cellular_component +def: "A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR." [GOC:signaling, PMID:16460914, PMID:1973074, Reactome:R-HSA-1227939, Reactome:R-HSA-1963573, Reactome:R-HSA-1963589] +synonym: "EGF:EGFR:ERBB2 complex" NARROW [Reactome:R-HSA-1963573] +synonym: "EGFR:ERBB2 heterodimer" RELATED [Reactome:R-HSA-1963573] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T02:10:38Z + +[Term] +id: GO:0038143 +name: ERBB3:ERBB2 complex +namespace: cellular_component +def: "A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3." [GOC:signaling, PMID:16460914, PMID:8665853, Reactome:R-HSA-1247502, Reactome:R-HSA-1963573, Reactome:R-HSA-1963589] +synonym: "EGFR:ERBB2 heterodimer" NARROW [Reactome:R-HSA-1963573] +synonym: "NRG1/2:ERBB3:ERBB2" NARROW [Reactome:R-HSA-1247502] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T02:16:56Z + +[Term] +id: GO:0038144 +name: ERBB4:ERBB2 complex +namespace: cellular_component +def: "A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4." [GOC:signaling, PMID:16460914, PMID:16978839, Reactome:R-HSA-1250224, Reactome:R-HSA-1963573, Reactome:R-HSA-1963589] +synonym: "ERBB4:ERBB2 heterodimer" NARROW [Reactome:R-HSA-1250224] +synonym: "NRGs/EGFLs:ERBB4:ERBB2" NARROW [Reactome:R-HSA-1250224] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: bf +creation_date: 2012-03-30T02:24:01Z + +[Term] +id: GO:0038145 +name: macrophage colony-stimulating factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, GOC:uh, PMID:12138890, PR:000005930, Wikipedia:Macrophage_colony-stimulating_factor] +synonym: "M-CSF signaling pathway" EXACT [PMID:12138890] +synonym: "macrophage colony-stimulating factor signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +created_by: bf +creation_date: 2012-04-27T11:04:18Z + +[Term] +id: GO:0038146 +name: chemokine (C-X-C motif) ligand 12 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PR:000006066, Wikipedia:Stromal_cell-derived_factor-1] +synonym: "CXCL12 signaling pathway" EXACT [GOC:bf] +synonym: "CXCL12-activated CXCR7 signaling pathway" NARROW [GOC:bf] +synonym: "SDF1 signaling pathway" EXACT [HGNC:10672, PMID:22204316, PR:000006066] +synonym: "stromal cell-derived factor-1 signaling pathway" EXACT [HGNC:10672, PMID:22204316, PR:000006066] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:26:17Z + +[Term] +id: GO:0038147 +name: C-X-C motif chemokine 12 receptor activity +namespace: molecular_function +def: "Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, PMID:22204316] +synonym: "CXCL12 receptor activity" EXACT [GOC:bf] +synonym: "CXCR4" NARROW [PMID:22204316] +synonym: "CXCR7" NARROW [PMID:22204316] +synonym: "SDF-1 receptor activity" RELATED [HGNC:10672, PR:000006066] +synonym: "stromal cell-derived factor-1 receptor activity" EXACT [HGNC:10672, PR:000006066] +is_a: GO:0016494 ! C-X-C chemokine receptor activity +relationship: part_of GO:0038146 ! chemokine (C-X-C motif) ligand 12 signaling pathway +created_by: bf +creation_date: 2012-05-11T11:32:53Z + +[Term] +id: GO:0038148 +name: chemokine (C-C motif) ligand 2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PR:000002122, Wikipedia:CCL2] +synonym: "CCL2 signaling pathway" EXACT [GOC:bf] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:36:08Z + +[Term] +id: GO:0038149 +name: C-C motif chemokine 2 receptor activity +namespace: molecular_function +def: "Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:signaling] +synonym: "CCL2 receptor activity" EXACT [GOC:bf] +is_a: GO:0016493 ! C-C chemokine receptor activity +relationship: part_of GO:0038148 ! chemokine (C-C motif) ligand 2 signaling pathway +created_by: bf +creation_date: 2012-05-11T11:37:16Z + +[Term] +id: GO:0038150 +name: C-C chemokine receptor CCR2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PR:000001199] +synonym: "C-C chemokine receptor type 2 signaling pathway" EXACT [PR:000001199] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:41:02Z + +[Term] +id: GO:0038151 +name: CCL2-activated CCR2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "CCL2/CCR2 signaling pathway" EXACT [GOC:bf] +is_a: GO:0038148 ! chemokine (C-C motif) ligand 2 signaling pathway +is_a: GO:0038150 ! C-C chemokine receptor CCR2 signaling pathway +created_by: bf +creation_date: 2012-05-11T11:41:58Z + +[Term] +id: GO:0038152 +name: C-C chemokine receptor CCR4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PR:000001200] +synonym: "C-C chemokine receptor type 4 signaling pathway" EXACT [PR:000001200] +synonym: "chemokine receptor CCR4 signaling pathway" EXACT [GOC:bf] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:43:34Z + +[Term] +id: GO:0038153 +name: CCL2-activated CCR4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "CCL2/CCR4 signaling pathway" RELATED [GOC:bf] +is_a: GO:0038148 ! chemokine (C-C motif) ligand 2 signaling pathway +is_a: GO:0038152 ! C-C chemokine receptor CCR4 signaling pathway +created_by: bf +creation_date: 2012-05-11T11:44:48Z + +[Term] +id: GO:0038154 +name: interleukin-11-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-11-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-11-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:48:37Z + +[Term] +id: GO:0038155 +name: interleukin-23-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-23-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-23-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:49:56Z + +[Term] +id: GO:0038156 +name: interleukin-3-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "IL-3-mediated signaling pathway" EXACT [GOC:bf] +synonym: "interleukin-3-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-11T11:50:42Z + +[Term] +id: GO:0038157 +name: granulocyte-macrophage colony-stimulating factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors." [GOC:nhn, GOC:signaling, PMID:17027509] +synonym: "CSF2 signaling pathway" EXACT [PR:000005931] +synonym: "GM-CSF receptor signaling pathway" EXACT [GOC:nhn] +synonym: "GM-CSF signaling pathway" EXACT [PR:000005931] +synonym: "granulocyte-macrophage colony-stimulating factor receptor signaling pathway" EXACT [GOC:nhn] +synonym: "granulocyte-macrophage colony-stimulating factor signalling pathway" RELATED [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T01:22:15Z + +[Term] +id: GO:0038158 +name: granulocyte colony-stimulating factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R)." [GOC:nhn, GOC:signaling] +synonym: "CSF3 signaling pathway" EXACT [PR:000005932] +synonym: "G-CSF receptor signaling pathway" EXACT [GOC:nhn] +synonym: "G-CSF signaling pathway" EXACT [PR:000005932] +synonym: "granulocyte colony-stimulating factor receptor signaling pathway" EXACT [GOC:nhn] +synonym: "granulocyte colony-stimulating factor signalling pathway" RELATED [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T01:30:28Z + +[Term] +id: GO:0038159 +name: C-X-C chemokine receptor CXCR4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling] +synonym: "CXCR4 signaling pathway" EXACT [PR:000001208] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T01:33:17Z + +[Term] +id: GO:0038160 +name: CXCL12-activated CXCR4 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn] +synonym: "CXCL12-activated CXCR4 signalling pathway" EXACT [GOC:bf] +is_a: GO:0038146 ! chemokine (C-X-C motif) ligand 12 signaling pathway +is_a: GO:0038159 ! C-X-C chemokine receptor CXCR4 signaling pathway +created_by: bf +creation_date: 2012-05-14T01:33:17Z + +[Term] +id: GO:0038161 +name: prolactin signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:21664429] +synonym: "PRL signaling pathway" EXACT [PMID:21664429, PR:000013246] +synonym: "prolactin-mediated signaling pathway" EXACT [GOC:bf] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0019221 ! cytokine-mediated signaling pathway +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-05-14T01:52:59Z + +[Term] +id: GO:0038162 +name: erythropoietin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, PMID:12489509] +synonym: "EPO-R signaling pathway" EXACT [PMID:12489509] +synonym: "erythropoietin receptor signaling pathway" EXACT [PMID:12489509] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0036018 ! cellular response to erythropoietin +created_by: bf +creation_date: 2012-05-14T02:28:38Z + +[Term] +id: GO:0038163 +name: thrombopoietin-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, GOC:signaling, PMID:19630807] +synonym: "THPO signaling pathway" EXACT [PR:000016318] +synonym: "THPO/MPL signaling pathway" EXACT [PMID:18371409] +synonym: "thrombopoietin receptor signaling pathway" EXACT [GOC:nhn, PR:000001939] +is_a: GO:0070098 ! chemokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T02:45:53Z + +[Term] +id: GO:0038164 +name: thrombopoietin receptor activity +namespace: molecular_function +def: "Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:signaling, PMID:19630807] +is_a: GO:0004896 ! cytokine receptor activity +relationship: part_of GO:0038163 ! thrombopoietin-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T02:46:58Z + +[Term] +id: GO:0038165 +name: oncostatin-M-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways." [GOC:nhn, GOC:signaling, PMID:10579456, PMID:12811586] +synonym: "oncostatin-M signaling pathway" EXACT [GOC:bf] +synonym: "OSM signaling pathway" EXACT [PMID:10579456, PR:000012059] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-05-14T02:54:30Z + +[Term] +id: GO:0038166 +name: angiotensin-activated signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nhn, GOC:signaling, PMID:10977869] +synonym: "angiotensin II-mediated signaling pathway" EXACT [GOC:bf] +synonym: "angiotensin receptor signaling pathway" EXACT [GOC:bf, GOC:mtg_cardiac_conduct_nov11] +synonym: "angiotensin-mediated signaling pathway" RELATED [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: part_of GO:1904385 ! cellular response to angiotensin +created_by: bf +creation_date: 2012-05-14T03:09:03Z + +[Term] +id: GO:0038167 +name: epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB." [GOC:signaling, GOC:uh, PMID:21229383, PMID:21518868, PMID:22132240] +synonym: "EGFR signaling pathway via activation of NF-kappaB" EXACT [GOC:bf] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: has_part GO:0051092 ! positive regulation of NF-kappaB transcription factor activity +created_by: bf +creation_date: 2012-05-15T11:49:30Z + +[Term] +id: GO:0038168 +name: epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB." [GOC:bf, PMID:22132240] +synonym: "EGFR signaling pathway via IKK-dependent activation of NF-kappaB" EXACT [GOC:bf] +synonym: "EGFR signaling pathway via IKK/NF-kappaB cascade" EXACT [GOC:bf] +is_a: GO:0038167 ! epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity +relationship: has_part GO:0007249 ! I-kappaB kinase/NF-kappaB signaling +created_by: bf +creation_date: 2012-05-15T12:01:09Z + +[Term] +id: GO:0038169 +name: somatostatin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, PMID:18006219, PMID:8769369, PR:000001555] +comment: In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'. +synonym: "SST receptor signaling pathway" EXACT [GOC:bf] +synonym: "SSTR signaling pathway" RELATED [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2012-06-12T10:30:01Z + +[Term] +id: GO:0038170 +name: somatostatin signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:nhn, GOC:signaling, PMID:18006219, Wikipedia:Somatostatin] +synonym: "somatostatin signalling pathway" EXACT [GOC:bf] +synonym: "somatostatin-activated somatostatin receptor signaling pathway" EXACT [GOC:bf] +synonym: "somatostatin-mediated signaling pathway" EXACT [GOC:bf] +synonym: "somatotrophin release inhibiting factor signaling pathway" EXACT [Wikipedia:Somatostatin] +synonym: "SRIF signaling pathway" EXACT [Wikipeda:Somatostatin] +synonym: "SST signaling pathway" EXACT [Wikipedia:Somatostatin] +is_a: GO:0009755 ! hormone-mediated signaling pathway +is_a: GO:0038169 ! somatostatin receptor signaling pathway +created_by: bf +creation_date: 2012-06-12T10:33:21Z + +[Term] +id: GO:0038171 +name: cannabinoid signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids." [GOC:bf, GOC:jc, GOC:signaling, Wikipedia:Cannabinoid] +synonym: "cannabinoid receptor signaling pathway" EXACT [GOC:bf] +synonym: "cannabinoid-activated signaling pathway" EXACT [GOC:bf] +synonym: "cannabinoid-mediated signaling pathway" EXACT [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2012-06-12T10:47:53Z + +[Term] +id: GO:0038172 +name: interleukin-33-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, GOC:signaling, PR:000001389] +synonym: "IL-33-mediated signaling pathway" EXACT [GOC:bf] +synonym: "IL33 signaling pathway" EXACT [PR:000001389] +synonym: "interleukin-33 signaling pathway" RELATED [GOC:jc] +synonym: "interleukin-33-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-06-12T10:57:35Z + +[Term] +id: GO:0038173 +name: interleukin-17A-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, GOC:signaling, PR:000001138] +synonym: "IL-17A-mediated signaling pathway" EXACT [GOC:bf] +synonym: "IL17A signaling pathway" EXACT [PR:000001138, Wikipedia:IL17A] +synonym: "IL17a signaling pathway" EXACT [GOC:jc] +synonym: "interleukin-17A signaling pathway" RELATED [GOC:jc] +synonym: "interleukin-17A-mediated signalling pathway" EXACT [GOC:bf] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: bf +creation_date: 2012-06-12T10:59:01Z + +[Term] +id: GO:0038174 +name: interleukin-17A receptor activity +namespace: molecular_function +def: "Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:bf, GOC:jc, GOC:signaling, PR:000001138] +is_a: GO:0030368 ! interleukin-17 receptor activity +relationship: part_of GO:0038173 ! interleukin-17A-mediated signaling pathway +created_by: bf +creation_date: 2012-06-12T11:01:25Z + +[Term] +id: GO:0038175 +name: negative regulation of SREBP signaling pathway in response to increased oxygen levels +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels." [GOC:al, PMID:22017871] +synonym: "negative regulation of SREBP-mediated signaling pathway in presence of oxygen" RELATED [PMID:22017871] +synonym: "negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels" EXACT [GOC:bf, GOC:vw] +is_a: GO:2000639 ! negative regulation of SREBP signaling pathway +relationship: part_of GO:0036295 ! cellular response to increased oxygen levels +created_by: bf +creation_date: 2012-07-20T01:28:59Z + +[Term] +id: GO:0038176 +name: positive regulation of SREBP signaling pathway in response to decreased oxygen levels +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels." [GOC:al, PMID:22017871] +synonym: "positive regulation of SREBP-mediated signaling pathway in absence of oxygen" RELATED [PMID:22017871] +synonym: "positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels" EXACT [GOC:bf, GOC:vw] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +is_a: GO:2000640 ! positive regulation of SREBP signaling pathway +relationship: part_of GO:0036294 ! cellular response to decreased oxygen levels +created_by: bf +creation_date: 2012-07-20T01:30:25Z + +[Term] +id: GO:0038177 +name: death receptor agonist activity +namespace: molecular_function +def: "Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor." [GOC:mtg_apoptosis, GOC:pr] +synonym: "death receptor activator activity" EXACT [GOC:pr] +is_a: GO:0048018 ! receptor ligand activity +relationship: has_part GO:0005123 ! death receptor binding +created_by: bf +creation_date: 2012-09-20T12:52:00Z + +[Term] +id: GO:0038178 +name: complement component C5a signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor." [GOC:jc, PMID:15313431, Wikipedia:Complement_component_5a] +synonym: "complement component C5a-induced signaling pathway" EXACT [GOC:jc] +is_a: GO:0002430 ! complement receptor mediated signaling pathway +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2012-09-21T10:55:00Z + +[Term] +id: GO:0038179 +name: neurotrophin signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons." [GOC:bf, GOC:jc, GOC:signaling, PMID:17466268, PR:000021998, Wikipedia:Neurotrophin] +comment: There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors. +synonym: "neurotrophin receptor signaling pathway" EXACT [PMID:22333586] +is_a: GO:0007166 ! cell surface receptor signaling pathway +relationship: part_of GO:0071363 ! cellular response to growth factor stimulus +created_by: bf +creation_date: 2013-03-27T17:22:44Z + +[Term] +id: GO:0038180 +name: nerve growth factor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, PMID:11520933, PR:000011194, Wikipedia:Nerve_growth_factor] +comment: Nerve growth factor (NGF) binds at least two classes of receptors: the p75 LNGFR (low-affinity nerve growth factor receptor) and TrkA, a transmembrane tyrosine kinase. +synonym: "nerve growth factor signalling pathway" EXACT [GOC:bf] +synonym: "NGF signaling pathway" EXACT [PR:000011194, Wikipedia:Nerve_growth_factor] +is_a: GO:0038179 ! neurotrophin signaling pathway +relationship: part_of GO:1990090 ! cellular response to nerve growth factor stimulus +created_by: bf +creation_date: 2013-05-15T11:04:05Z + +[Term] +id: GO:0038181 +name: bile acid receptor activity +namespace: molecular_function +def: "Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile." [GOC:bf, PMID:10334992, PMID:12718893] +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0032052 ! bile acid binding +relationship: part_of GO:0038183 ! bile acid signaling pathway +created_by: bf +creation_date: 2013-05-16T10:27:02Z + +[Term] +id: GO:0038182 +name: G protein-coupled bile acid receptor activity +namespace: molecular_function +def: "Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, PMID:12524422, Wikipedia:G_protein-coupled_bile_acid_receptor] +synonym: "cell surface bile acid receptor" BROAD [GOC:bf] +synonym: "G-protein coupled bile acid receptor activity" EXACT [] +synonym: "membrane bile acid receptor activity" BROAD [PMID:12419312] +xref: Wikipedia:G_protein-coupled_bile_acid_receptor +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0038181 ! bile acid receptor activity +relationship: part_of GO:0038184 ! cell surface bile acid receptor signaling pathway +created_by: bf +creation_date: 2013-05-16T10:29:42Z + +[Term] +id: GO:0038183 +name: bile acid signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:signaling, PMID:12016314] +is_a: GO:0007165 ! signal transduction +created_by: bf +creation_date: 2013-05-16T10:35:10Z + +[Term] +id: GO:0038184 +name: cell surface bile acid receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, PMID:12419312, PMID:19442546] +synonym: "membrane bile acid receptor signaling pathway" RELATED [GOC:bf] +is_a: GO:0007166 ! cell surface receptor signaling pathway +is_a: GO:0038183 ! bile acid signaling pathway +created_by: bf +creation_date: 2013-05-16T11:00:42Z + +[Term] +id: GO:0038185 +name: intracellular bile acid receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, PMID:10334992] +synonym: "nuclear bile acid receptor signaling pathway" RELATED [] +is_a: GO:0030522 ! intracellular receptor signaling pathway +is_a: GO:0038183 ! bile acid signaling pathway +created_by: bf +creation_date: 2013-05-16T11:08:02Z + +[Term] +id: GO:0038186 +name: lithocholic acid receptor activity +namespace: molecular_function +def: "Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity." [GOC:bf, PMID:12016314, PMID:12419312] +synonym: "LCA receptor activity" EXACT [PMID:10334992] +is_a: GO:0038181 ! bile acid receptor activity +relationship: has_part GO:1902121 ! lithocholic acid binding +created_by: bf +creation_date: 2013-05-16T11:13:38Z + +[Term] +id: GO:0038187 +name: pattern recognition receptor activity +namespace: molecular_function +alt_id: GO:0008329 +def: "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response." [GOC:ar, GOC:bf, Wikipedia:Pattern_recognition_receptor] +synonym: "macrophage receptor activity" RELATED [] +synonym: "MAMP receptor activity" NARROW [] +synonym: "microbe-associated molecular pattern receptor activity" NARROW [] +synonym: "PAMP receptor activity" NARROW [] +synonym: "pathogen associated molecular pattern receptor activity" NARROW [] +synonym: "PRR" EXACT [] +synonym: "PRR activity" EXACT [Wikipedia:Pattern_recognition_receptor] +synonym: "signaling pattern recognition receptor activity" RELATED [] +is_a: GO:0038023 ! signaling receptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17995 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18588 xsd:anyURI +created_by: bf +creation_date: 2013-05-29T15:24:44Z + +[Term] +id: GO:0038188 +name: cholecystokinin signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:jc, PMID:11181948] +synonym: "CCK signaling" EXACT [PMID:11181948, Wikipedia:Cholecystokinin] +synonym: "cholecystokinin receptor signaling pathway" RELATED [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2013-07-01T13:05:46Z + +[Term] +id: GO:0038189 +name: neuropilin signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, PMID:12852851] +synonym: "Npn signaling" EXACT [PMID:12852851] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2013-08-01T16:02:10Z + +[Term] +id: GO:0038190 +name: VEGF-activated neuropilin signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:rl, PMID:12852851] +synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway" RELATED [GOC:bf] +synonym: "VEGF-Npn-1 signaling" NARROW [PMID:12852851] +is_a: GO:0038084 ! vascular endothelial growth factor signaling pathway +is_a: GO:0038189 ! neuropilin signaling pathway +relationship: has_part GO:0005021 ! vascular endothelial growth factor-activated receptor activity +created_by: bf +creation_date: 2013-08-01T16:06:49Z + +[Term] +id: GO:0038191 +name: neuropilin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a member of the neuropilin family." [GOC:bf, PMID:23871893] +synonym: "neuropilin-binding" EXACT [PMID:12852851] +synonym: "Nrp binding" EXACT [PMID:23871893] +synonym: "Nrp ligand" NARROW [PMID:23871893] +is_a: GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2013-08-01T16:11:33Z + +[Term] +id: GO:0038192 +name: gastric inhibitory peptide signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, PMID:15955806] +synonym: "gastric inhibitory polypeptide receptor signaling pathway" EXACT [GOC:nhn] +synonym: "GIP signaling" EXACT [PMID:19251046] +synonym: "glucose-dependent insulinotropic polypeptide signaling" EXACT [PMID:19251046] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2013-09-02T15:57:49Z + +[Term] +id: GO:0038193 +name: thromboxane A2 signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:nhn, PMID:15893915] +synonym: "TXA(2) receptor signaling" EXACT [PMID:15893915] +synonym: "TXA2 signaling" EXACT [PMID:15242977] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2013-09-02T16:07:01Z + +[Term] +id: GO:0038194 +name: thyroid-stimulating hormone signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:gap, PMID:10809230] +synonym: "thyrotropin signaling pathway" EXACT [GOC:gap, PMID:10809230] +synonym: "TSH signaling pathway" EXACT [PMID:10809230] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf +creation_date: 2013-10-28T09:03:48Z + +[Term] +id: GO:0038195 +name: urokinase plasminogen activator signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:gap, PMID:9417082] +synonym: "uPA signaling pathway" EXACT [PMID:9417082] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: bf +creation_date: 2013-10-28T09:14:13Z + +[Term] +id: GO:0038196 +name: type III interferon signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far." [GOC:pg, GOC:signaling] +synonym: "interferon lambda signaling pathway" NARROW [PR:000001362] +synonym: "type III interferon-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071358 ! cellular response to type III interferon +created_by: bf +creation_date: 2013-11-27T14:25:49Z + +[Term] +id: GO:0038197 +name: type I interferon receptor complex +namespace: cellular_component +def: "A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2)." [GOC:cjm, GOC:signaling, PMID:17502368] +synonym: "interferon-alpha/beta receptor complex" NARROW [GOC:bf] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bf +creation_date: 2013-11-27T14:53:50Z + +[Term] +id: GO:0038198 +name: auxin receptor activity +namespace: molecular_function +def: "Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone)." [GOC:signaling, PMID:15917797] +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0010011 ! auxin binding +relationship: part_of GO:0009734 ! auxin-activated signaling pathway +created_by: bf +creation_date: 2013-12-05T15:47:42Z + +[Term] +id: GO:0038199 +name: ethylene receptor activity +namespace: molecular_function +def: "Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity." [GOC:signaling, PMID:22467798, PMID:24012247] +synonym: "C2H4 receptor activity" EXACT [PMID:24012247] +synonym: "ethylene response sensor" RELATED [PMID:22467798] +is_a: GO:0038023 ! signaling receptor activity +relationship: has_part GO:0051740 ! ethylene binding +relationship: part_of GO:0009873 ! ethylene-activated signaling pathway +created_by: bf +creation_date: 2013-12-05T16:06:13Z + +[Term] +id: GO:0038200 +name: ethylene receptor histidine kinase activity +namespace: molecular_function +def: "Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate." [GOC:signaling, PMID:22467798] +is_a: GO:0038199 ! ethylene receptor activity +relationship: has_part GO:0004673 ! protein histidine kinase activity +created_by: bf +creation_date: 2013-12-05T16:25:15Z + +[Term] +id: GO:0038201 +name: TOR complex +namespace: cellular_component +def: "A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K." [Wikipedia:MTORC1, Wikipedia:MTORC2] +synonym: "mTOR complex" NARROW [Wikipedia:MTORC1] +synonym: "target of rapamycin complex" EXACT [GOC:bf] +synonym: "TOR signaling complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: bf +creation_date: 2013-12-09T14:38:09Z + +[Term] +id: GO:0038202 +name: TORC1 signaling +namespace: biological_process +def: "A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components." [GOC:lb] +synonym: "TORC1 signal transduction" EXACT [GOC:signaling] +is_a: GO:0031929 ! TOR signaling +created_by: bf +creation_date: 2013-12-09T14:43:29Z + +[Term] +id: GO:0038203 +name: TORC2 signaling +namespace: biological_process +def: "A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components." [GOC:lb] +synonym: "TORC2 signal transduction" EXACT [GOC:signaling] +is_a: GO:0031929 ! TOR signaling +created_by: bf +creation_date: 2013-12-09T14:43:29Z + +[Term] +id: GO:0039003 +name: pronephric field specification +namespace: biological_process +def: "The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop." [GOC:mtg_kidney_jan10] +synonym: "pronephric kidney field specification" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0039017 ! pattern specification involved in pronephros development +is_a: GO:0072004 ! kidney field specification +created_by: bf +creation_date: 2010-07-02T09:28:16Z + +[Term] +id: GO:0039004 +name: specification of pronephric proximal tubule identity +namespace: biological_process +def: "The process in which the proximal tubule of the pronephric nephron acquires its identity." [GOC:mtg_kidney_jan10] +is_a: GO:0039005 ! specification of pronephric tubule identity +is_a: GO:0072082 ! specification of proximal tubule identity +is_a: GO:0072196 ! proximal/distal pattern formation involved in pronephric nephron development +relationship: part_of GO:0039011 ! pronephric proximal tubule morphogenesis +created_by: bf +creation_date: 2010-07-02T09:30:30Z + +[Term] +id: GO:0039005 +name: specification of pronephric tubule identity +namespace: biological_process +def: "The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity." [GOC:mtg_kidney_jan10] +is_a: GO:0039017 ! pattern specification involved in pronephros development +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis +created_by: bf +creation_date: 2010-07-02T09:33:56Z + +[Term] +id: GO:0039006 +name: pronephric nephron tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10] +synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10] +synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072079 ! nephron tubule formation +relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis +relationship: part_of GO:0072116 ! pronephros formation +created_by: bf +creation_date: 2010-07-02T09:37:27Z + +[Term] +id: GO:0039007 +name: pronephric nephron morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0039019 ! pronephric nephron development +relationship: part_of GO:0072114 ! pronephros morphogenesis +created_by: bf +creation_date: 2010-07-02T09:38:53Z + +[Term] +id: GO:0039008 +name: pronephric nephron tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558] +is_a: GO:0072078 ! nephron tubule morphogenesis +relationship: part_of GO:0039007 ! pronephric nephron morphogenesis +relationship: part_of GO:0039020 ! pronephric nephron tubule development +created_by: bf +creation_date: 2010-07-02T09:45:55Z + +[Term] +id: GO:0039009 +name: rectal diverticulum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior." [GOC:mtg_kidney_jan10, PMID:10535314, PMID:18226983, XAO:0001015] +synonym: "pronephric rectal diverticulum development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T09:48:58Z + +[Term] +id: GO:0039010 +name: specification of pronephric distal tubule identity +namespace: biological_process +def: "The process in which the distal tubule of the pronephric nephron acquires its identity." [GOC:mtg_kidney_jan10] +is_a: GO:0039005 ! specification of pronephric tubule identity +is_a: GO:0072084 ! specification of distal tubule identity +is_a: GO:0072196 ! proximal/distal pattern formation involved in pronephric nephron development +relationship: part_of GO:0039013 ! pronephric distal tubule morphogenesis +created_by: bf +creation_date: 2010-07-02T09:51:28Z + +[Term] +id: GO:0039011 +name: pronephric proximal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10] +synonym: "pronephros proximal tubule morphogenesis" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0039008 ! pronephric nephron tubule morphogenesis +is_a: GO:0072158 ! proximal tubule morphogenesis +relationship: part_of GO:0035776 ! pronephric proximal tubule development +created_by: bf +creation_date: 2010-07-02T09:53:12Z + +[Term] +id: GO:0039012 +name: pronephric sinus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules." [GOC:mtg_kidney_jan10, PMID:10535314, XAO:0000385] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T09:55:23Z + +[Term] +id: GO:0039013 +name: pronephric distal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros." [GOC:mtg_kidney_jan10] +is_a: GO:0039008 ! pronephric nephron tubule morphogenesis +is_a: GO:0072156 ! distal tubule morphogenesis +relationship: part_of GO:0035777 ! pronephric distal tubule development +created_by: bf +creation_date: 2010-07-02T09:58:03Z + +[Term] +id: GO:0039014 +name: cell differentiation involved in pronephros development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0048793 ! pronephros development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T09:59:25Z + +[Term] +id: GO:0039015 +name: cell proliferation involved in pronephros development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10] +synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072111 ! cell proliferation involved in kidney development +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0048793 ! pronephros development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:01:49Z + +[Term] +id: GO:0039016 +name: cell-cell signaling involved in pronephros development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] +synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah] +is_a: GO:0060995 ! cell-cell signaling involved in kidney development +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0048793 ! pronephros development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:03:16Z + +[Term] +id: GO:0039017 +name: pattern specification involved in pronephros development +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] +synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061004 ! pattern specification involved in kidney development +intersection_of: GO:0007389 ! pattern specification process +intersection_of: part_of GO:0048793 ! pronephros development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:04:39Z + +[Term] +id: GO:0039018 +name: nephrostome development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity." [GOC:mtg_kidney_jan10, PMID:14686690, PMID:15647339, XAO:0000062] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:08:16Z + +[Term] +id: GO:0039019 +name: pronephric nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785] +is_a: GO:0072006 ! nephron development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:10:20Z + +[Term] +id: GO:0039020 +name: pronephric nephron tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0039019 ! pronephric nephron development +created_by: bf +creation_date: 2010-07-02T10:11:36Z + +[Term] +id: GO:0039021 +name: pronephric glomerulus development +namespace: biological_process +def: "The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment." [GOC:dgh, GOC:mtg_kidney_jan10, ZFA:00001557] +comment: This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus. +is_a: GO:0032835 ! glomerulus development +relationship: part_of GO:0039019 ! pronephric nephron development +created_by: bf +creation_date: 2010-07-02T10:13:38Z + +[Term] +id: GO:0039022 +name: pronephric duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] +is_a: GO:0072176 ! nephric duct development +relationship: part_of GO:0048793 ! pronephros development +created_by: bf +creation_date: 2010-07-02T10:15:03Z + +[Term] +id: GO:0039023 +name: pronephric duct morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150] +is_a: GO:0072178 ! nephric duct morphogenesis +relationship: part_of GO:0039022 ! pronephric duct development +relationship: part_of GO:0072114 ! pronephros morphogenesis +created_by: bf +creation_date: 2010-07-02T10:18:09Z + +[Term] +id: GO:0039501 +name: suppression by virus of host type I interferon production +namespace: biological_process +def: "Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:bf, GOC:sp, UniProtKB-KW:KW-1113, VZ:875] +synonym: "negative regulation by virus of host type I interferon production" EXACT [GOC:bf] +synonym: "suppression by virus of host interferon type I production" EXACT [GOC:bf] +synonym: "suppression by virus of host type I IFN production" EXACT [GOC:bf] +xref: VZ:875 "Inhibition of host IFN-mediated response initiation by virus" +is_a: GO:0032480 ! negative regulation of type I interferon production +is_a: GO:0046775 ! suppression by virus of host cytokine production +created_by: bf +creation_date: 2011-05-11T03:53:20Z + +[Term] +id: GO:0039502 +name: suppression by virus of host type I interferon-mediated signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:bf, GOC:sp, UniProtKB-KW:KW-1114, VZ:883] +synonym: "inhibition of host interferon signaling pathway by virus" RELATED [UniProtKB-KW:KW-1114] +synonym: "negative regulation by virus of host type I interferon-mediated signaling pathway" EXACT [GOC:bf] +synonym: "suppression by virus of host type I IFN-mediated signaling pathway" EXACT [GOC:bf] +synonym: "suppression by virus of host type I interferon-mediated signalling pathway" EXACT [GOC:bf] +xref: VZ:883 "Inhibition of host IFN-mediated response initiation by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0060339 ! negative regulation of type I interferon-mediated signaling pathway +is_a: GO:0075114 ! suppression by symbiont of host transmembrane receptor-mediated signal transduction +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0060337 ! type I interferon signaling pathway +created_by: bf +creation_date: 2011-05-11T04:06:28Z + +[Term] +id: GO:0039503 +name: suppression by virus of host innate immune response +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense." [GOC:add, GOC:bf, GOC:sp, UniProtKB-KW:KW-1090] +synonym: "inhibition of host innate immune response by virus" EXACT [UniProtKB-KW:KW-1090] +synonym: "negative regulation by virus of host innate immune response" EXACT [GOC:bf] +synonym: "negative regulation by virus of host innate immunity" EXACT [GOC:bf] +synonym: "suppression by virus of host innate immunity" EXACT [GOC:pg] +is_a: GO:0030683 ! mitigation of host immune response by virus +is_a: GO:0052170 ! suppression by symbiont of host innate immune response +is_a: GO:0075528 ! modulation by virus of host immune response +created_by: bf +creation_date: 2011-05-11T04:31:17Z + +[Term] +id: GO:0039504 +name: suppression by virus of host adaptive immune response +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)." [GOC:add, GOC:bf, GOC:sp, UniProtKB-KW:KW-1080] +synonym: "inhibition of host adaptive immune response by virus" EXACT [UniProtKB-KW:KW-1080] +synonym: "negative regulation by virus of host adaptive immune response" EXACT [GOC:bf] +synonym: "negative regulation by virus of host adaptive immunity" EXACT [GOC:bf] +synonym: "suppression by virus of host acquired immune response" EXACT [ISBN:068340007X] +is_a: GO:0002820 ! negative regulation of adaptive immune response +is_a: GO:0030683 ! mitigation of host immune response by virus +is_a: GO:0052562 ! suppression by symbiont of host immune response +is_a: GO:0075528 ! modulation by virus of host immune response +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0002250 ! adaptive immune response +created_by: bf +creation_date: 2011-05-11T04:41:54Z + +[Term] +id: GO:0039505 +name: suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II +namespace: biological_process +def: "Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex." [GOC:add, GOC:bf, UniProtKB-KW:KW-1116, VZ:820] +synonym: "inhibition of host MHC class II molecule presentation by virus" RELATED [UniProtKB-KW:KW-1116] +xref: VZ:820 "Inhibition of host MHC class II molecule presentation by virus" +is_a: GO:0002587 ! negative regulation of antigen processing and presentation of peptide antigen via MHC class II +is_a: GO:0039588 ! suppression by virus of host antigen processing and presentation +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0002495 ! antigen processing and presentation of peptide antigen via MHC class II +created_by: bf +creation_date: 2011-06-02T02:34:51Z + +[Term] +id: GO:0039506 +name: modulation by virus of host molecular function +namespace: biological_process +def: "The process in which a virus effects a change in the function of a host protein via a direct interaction." [GOC:bf, GOC:sp] +synonym: "modification by virus of host protein function" EXACT [GOC:bf] +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0003674 ! molecular_function +created_by: bf +creation_date: 2011-06-02T02:38:42Z + +[Term] +id: GO:0039507 +name: suppression by virus of host molecular function +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein." [GOC:bf, GOC:sp] +synonym: "down regulation by virus of host protein function" EXACT [GOC:bf] +synonym: "down-regulation by virus of host protein function" EXACT [GOC:bf] +synonym: "inhibition by virus of host protein function" NARROW [GOC:bf] +synonym: "inhibition of host protein function" NARROW [GOC:bf] +synonym: "negative regulation by virus of host molecular function" EXACT [GOC:bf] +synonym: "negative regulation by virus of host protein function" EXACT [GOC:bf] +is_a: GO:0039506 ! modulation by virus of host molecular function +is_a: GO:0052056 ! negative regulation by symbiont of host molecular function +created_by: bf +creation_date: 2011-06-02T02:47:03Z + +[Term] +id: GO:0039508 +name: suppression by virus of host receptor activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor." [GOC:bf, GOC:sp] +synonym: "down-regulation by virus of host receptor activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host receptor activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host receptor activity" NARROW [GOC:bf] +synonym: "negative regulation by virus of host receptor activity" EXACT [GOC:bf] +synonym: "suppression by virus of host receptor function" EXACT [GOC:bf] +synonym: "viral inhibition of host receptor" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: bf +creation_date: 2011-06-02T03:09:37Z + +[Term] +id: GO:0039509 +name: suppression by virus of host pattern recognition receptor activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity." [GOC:bf, GOC:sp] +synonym: "down regulation by virus of host pattern recognition receptor activity" EXACT [GOC:bf] +synonym: "down-regulation by virus of host pattern recognition receptor activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host pattern recognition receptor activity" NARROW [GOC:rf] +synonym: "negative regulation by virus of host pattern recognition receptor activity" EXACT [GOC:bf] +synonym: "suppression by virus of host pattern recognition receptor function" EXACT [GOC:bf] +synonym: "viral inhibition of host pattern recognition receptor activity" NARROW [GOC:bf] +is_a: GO:0039508 ! suppression by virus of host receptor activity +created_by: bf +creation_date: 2011-06-02T03:11:23Z + +[Term] +id: GO:0039510 +name: suppression by virus of host ATP-dependent RNA helicase activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity." [GOC:bf, GOC:sp] +synonym: "down-regulation by virus of host ATP-dependent RNA helicase activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host ATP-dependent RNA helicase activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host ATP-dependent RNA helicase activity" NARROW [GOC:bf] +synonym: "negative regulation by virus of host ATP-dependent RNA helicase activity" EXACT [GOC:bf] +is_a: GO:0039513 ! suppression by virus of host catalytic activity +created_by: bf +creation_date: 2011-06-16T02:11:00Z + +[Term] +id: GO:0039511 +name: suppression by virus of host interferon receptor activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1091, VZ:843] +synonym: "down-regulation by virus of host interferon receptor activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host interferon receptor activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host interferon receptor activity" NARROW [GOC:bf] +synonym: "inhibition of host interferon receptors by virus" EXACT [UniProtKB-KW:KW-1091] +synonym: "negative regulation by virus of host interferon receptor activity" EXACT [GOC:bf] +xref: VZ:843 "Inhibition of host interferon receptors by virus" +is_a: GO:0039508 ! suppression by virus of host receptor activity +created_by: bf +creation_date: 2011-06-16T02:24:05Z + +[Term] +id: GO:0039512 +name: suppression by virus of host protein tyrosine kinase activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity." [GOC:bf, GOC:sp] +synonym: "down-regulation by virus of host protein tyrosine kinase activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host protein tyrosine kinase activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host protein tyrosine kinase activity" NARROW [GOC:bf] +synonym: "negative regulation by virus of host protein tyrosine kinase activity" EXACT [GOC:bf] +is_a: GO:0039584 ! suppression by virus of host protein kinase activity +created_by: bf +creation_date: 2011-06-16T02:27:26Z + +[Term] +id: GO:0039513 +name: suppression by virus of host catalytic activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity." [GOC:bf] +synonym: "down-regulation by virus of host enzyme activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host catalytic activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host catalytic activity" NARROW [GOC:bf] +synonym: "negative regulation by virus of host catalytic activity" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039516 ! modulation by virus of host catalytic activity +is_a: GO:0052053 ! negative regulation by symbiont of host catalytic activity +created_by: bf +creation_date: 2011-06-16T02:32:49Z + +[Term] +id: GO:0039514 +name: suppression by virus of host JAK-STAT cascade +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism." [GOC:bf, GOC:sp] +synonym: "down-regulation by virus of host JAK-STAT cascade" EXACT [GOC:bf] +synonym: "downregulation by virus of host JAK-STAT cascade" EXACT [GOC:bf] +synonym: "inhibition by virus of host JAK-STAT cascade" NARROW [GOC:bf] +synonym: "negative regulation by virus of host JAK-STAT cascade" EXACT [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +created_by: bf +creation_date: 2011-06-16T02:48:03Z + +[Term] +id: GO:0039516 +name: modulation by virus of host catalytic activity +namespace: biological_process +def: "The process in which a virus effects a change in host enzyme activity." [GOC:bf, GOC:sp] +synonym: "modulation of catalytic activity of host by virus" EXACT [GOC:bf] +synonym: "regulation by virus of host catalytic activity" EXACT [GOC:bf] +synonym: "regulation of host catalytic activity by virus" EXACT [GOC:bf] +is_a: GO:0039506 ! modulation by virus of host molecular function +is_a: GO:0052148 ! modulation by symbiont of host catalytic activity +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0003824 ! catalytic activity +created_by: bf +creation_date: 2011-06-16T02:59:35Z + +[Term] +id: GO:0039517 +name: modulation by virus of host protein serine/threonine phosphatase activity +namespace: biological_process +def: "The process in which a virus effects a change in host protein serine/threonine phosphatase activity." [GOC:bf, GOC:sp] +synonym: "modulation by virus of protein serine/threonine phosphatase activity in host" EXACT [GOC:bf] +synonym: "regulation by virus of host protein serine/threonine phosphatase activity" EXACT [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0039516 ! modulation by virus of host catalytic activity +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0004722 ! protein serine/threonine phosphatase activity +relationship: regulates GO:0004722 ! protein serine/threonine phosphatase activity +created_by: bf +creation_date: 2011-06-16T03:04:14Z + +[Term] +id: GO:0039518 +name: suppression by virus of host cytokine activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity." [GOC:bf, GOC:sp] +synonym: "down-regulation by virus of host cytokine activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host cytokine activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host cytokine activity" NARROW [GOC:bf] +synonym: "negative regulation by virus of host cytokine activity" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: bf +creation_date: 2011-06-22T04:09:41Z + +[Term] +id: GO:0039519 +name: modulation by virus of host autophagy +namespace: biological_process +def: "Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host." [GOC:bf, GOC:sp] +synonym: "regulation by virus of host autophagy" EXACT [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052040 ! modulation by symbiont of host programmed cell death +is_a: GO:0075071 ! modulation by symbiont of host autophagy +is_a: GO:1904092 ! regulation of autophagic cell death +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0048102 ! autophagic cell death +created_by: bf +creation_date: 2011-06-22T04:19:19Z + +[Term] +id: GO:0039520 +name: induction by virus of host autophagy +namespace: biological_process +def: "Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1072, VZ:846] +synonym: "activation of host autophagy by virus" EXACT [UniProtKB-KW:KW-1072] +synonym: "positive regulation by virus of host autophagy" BROAD [GOC:bf] +xref: VZ:846 "Activation of host autophagy by virus" +is_a: GO:0039519 ! modulation by virus of host autophagy +is_a: GO:0075044 ! positive regulation by symbiont of host autophagy +created_by: bf +creation_date: 2011-06-22T04:24:47Z + +[Term] +id: GO:0039521 +name: suppression by virus of host autophagy +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1083, VZ:845] +synonym: "inhibition by virus of host autophagy" EXACT [GOC:bf] +synonym: "inhibition of host autophagy by virus" EXACT [UniProtKB-KW:KW-1083] +synonym: "negative regulation by virus of host autophagy" BROAD [GOC:bf] +xref: VZ:845 "Inhibition of host autophagy by virus" +is_a: GO:0039519 ! modulation by virus of host autophagy +is_a: GO:0140321 ! negative regulation by symbiont of host autophagy +created_by: bf +creation_date: 2011-06-22T04:30:11Z + +[Term] +id: GO:0039522 +name: suppression by virus of host mRNA export from nucleus +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1099, VZ:902] +synonym: "inhibition by virus of host mRNA nuclear export" EXACT [GOC:bf] +synonym: "inhibition of host mRNA nuclear export by virus" EXACT [UniProtKB-KW:KW-1099] +synonym: "negative regulation by virus of host mRNA nuclear export" BROAD [GOC:bf] +synonym: "suppression of host mRNA nuclear export by virus" EXACT [GOC:bf] +xref: VZ:902 "Inhibition of host mRNA nuclear export by virus" +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052038 ! modulation by symbiont of host intracellular transport +created_by: bf +creation_date: 2011-06-22T04:34:14Z + +[Term] +id: GO:0039523 +name: suppression by virus of host RNA polymerase II activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host RNA polymerase II activity." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1104, VZ:905] +synonym: "inhibition of host RNA polymerase II activity by virus" EXACT [GOC:bf] +synonym: "inhibition of host RNA polymerase II by virus" EXACT [UniProtKB-KW:KW-1104] +synonym: "negative regulation by virus of host RNA polymerase II activity" BROAD [GOC:bf] +xref: VZ:905 "Inhibition of host RNA polymerase II by virus" +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2011-06-22T04:38:59Z + +[Term] +id: GO:0039524 +name: suppression by virus of host mRNA processing +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1103, VZ:903] +synonym: "inhibition by virus of host mRNA processing" EXACT [GOC:bf] +synonym: "inhibition of host mRNA processing by virus" EXACT [GOC:bf] +synonym: "inhibition of host pre-mRNA processing by virus" EXACT [UniProtKB-KW:KW-1103, VZ:903] +synonym: "negative regulation by virus of host mRNA processing" BROAD [GOC:bf] +xref: VZ:903 "Inhibition of host pre-mRNA processing by virus" +is_a: GO:0039657 ! suppression by virus of host gene expression +is_a: GO:0046778 ! modification by virus of host mRNA processing +is_a: GO:0050686 ! negative regulation of mRNA processing +created_by: bf +creation_date: 2011-06-22T04:51:55Z + +[Term] +id: GO:0039525 +name: modulation by virus of host chromatin organization +namespace: biological_process +def: "Any process in which a virus effects a change in the organization of chromatin in the host." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1122] +synonym: "modulation by virus of host chromatin organisation" EXACT [GOC:mah] +synonym: "modulation of host chromatin by virus" EXACT [UniProtKB-KW:KW-1122] +synonym: "modulation of host chromatin structure by virus" EXACT [GOC:bf] +synonym: "regulation by virus of host chromatin organization" RELATED [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0006325 ! chromatin organization +created_by: bf +creation_date: 2011-06-22T05:11:13Z + +[Term] +id: GO:0039526 +name: modulation by virus of host apoptotic process +namespace: biological_process +def: "Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells." [GOC:bf, GOC:mtg_apoptosis, GOC:sp, UniProtKB-KW:KW-1119] +synonym: "modulation by virus of host apoptosis" EXACT [] +synonym: "modulation of host cell apoptosis by virus" EXACT [UniProtKB-KW:KW-1119] +synonym: "regulation by virus of host apoptosis" EXACT [GOC:bf] +xref: VZ:1581 "Apoptosis modulation" +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052150 ! modulation by symbiont of host apoptotic process +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0006915 ! apoptotic process +created_by: bf +creation_date: 2011-06-22T05:22:53Z + +[Term] +id: GO:0039527 +name: suppression by virus of host TRAF-mediated signal transduction +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host." [GOC:bf, GOC:sp] +synonym: "inhibition of host TRAF-mediated signal transduction by virus" EXACT [GOC:bf] +synonym: "negative regulation by virus of host TRAF-mediated signal transduction" BROAD [GOC:bf] +synonym: "suppression by virus of host tumor necrosis factor receptor-associated factor signaling" EXACT [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +created_by: bf +creation_date: 2011-06-22T05:30:41Z + +[Term] +id: GO:0039528 +name: cytoplasmic pattern recognition receptor signaling pathway in response to virus +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." [GOC:bf, PMID:17328678, PMID:18272355, PMID:19531363] +comment: This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has detected the viral RNA. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2. +synonym: "cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway" NARROW [PMID:17328678] +synonym: "cytoplasmic pattern recognition receptor signalling pathway in response to virus" EXACT [GOC:mah] +synonym: "RIG-I-like receptor (RLR) signaling pathway" NARROW [PMID:21626883] +synonym: "RIG-I/MDA5 signaling pathway" NARROW [PMID:21187438] +synonym: "RIG-like helicase signaling pathway" NARROW [PMID:18272355] +synonym: "RIG-like receptor signaling pathway" NARROW [PMID:19531363] +synonym: "RLH signaling pathway" NARROW [PMID:18272355] +synonym: "RLR signaling pathway" NARROW [PMID:19531363] +synonym: "virus-induced cytoplasmic pattern recognition receptor signaling pathway" EXACT [GOC:bf] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0002753 ! cytoplasmic pattern recognition receptor signaling pathway +is_a: GO:0098586 ! cellular response to virus +intersection_of: GO:0002753 ! cytoplasmic pattern recognition receptor signaling pathway +intersection_of: part_of GO:0051607 ! defense response to virus +relationship: part_of GO:0051607 ! defense response to virus +created_by: bf +creation_date: 2011-12-20T02:43:15Z + +[Term] +id: GO:0039529 +name: RIG-I signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." [GOC:bf, PMID:17328678, PMID:19620789, PMID:21435580] +comment: The apoptosis effect triggered by the RIG-I signaling pathway is inconclusive and may represent an in-vitro phenomenon. Therefore, in GO the term 'RIG-I signaling pathway ; GO:0039529' is positioned under 'regulation of cytokine production' as this is its primary effect. +synonym: "DDX58 signaling pathway" EXACT [HGNC:19102] +synonym: "retinoic acid inducible gene I signaling pathway" EXACT [HGNC:19102] +synonym: "RIG-I signalling pathway" EXACT [GOC:mah] +is_a: GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +created_by: bf +creation_date: 2011-12-20T03:11:06Z + +[Term] +id: GO:0039530 +name: MDA-5 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." [GOC:bf, PMID:19620789] +synonym: "IFIH1 signaling pathway" EXACT [HGNC:18873] +synonym: "MDA-5 signalling pathway" EXACT [GOC:mah] +synonym: "MDA5 signaling pathway" NARROW [PMID:17328678] +synonym: "melanoma differentiation-associated gene 5 signaling pathway" EXACT [HGNC:18873] +is_a: GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +created_by: bf +creation_date: 2011-12-20T03:14:52Z + +[Term] +id: GO:0039531 +name: regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm." [GOC:bf, GOC:jl] +synonym: "regulation of MAV signaling" RELATED [GOC:bf, GOC:sp] +synonym: "regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0050688 ! regulation of defense response to virus +is_a: GO:0062207 ! regulation of pattern recognition receptor signaling pathway +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +relationship: regulates GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +created_by: bf +creation_date: 2012-01-03T11:06:56Z + +[Term] +id: GO:0039532 +name: negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm." [GOC:bf, GOC:jl] +synonym: "negative regulation of cytoplasmic pattern recognition receptor signaling pathway in response to virus" EXACT [GOC:bf] +synonym: "negative regulation of MAVS signaling" RELATED [GOC:bf] +synonym: "negative regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0039531 ! regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +is_a: GO:0050687 ! negative regulation of defense response to virus +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +relationship: negatively_regulates GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus +created_by: bf +creation_date: 2012-01-03T11:14:48Z + +[Term] +id: GO:0039533 +name: regulation of MDA-5 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA." [GOC:bf, GOC:jl] +synonym: "regulation of IFIH1 signaling pathway" EXACT [HGNC:18873] +synonym: "regulation of MDA-5 signalling pathway" EXACT [GOC:mah] +synonym: "regulation of MDA5 signaling pathway" EXACT [PMID:17328678] +synonym: "regulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [HGNC:18873] +is_a: GO:0039531 ! regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039530 ! MDA-5 signaling pathway +relationship: regulates GO:0039530 ! MDA-5 signaling pathway +created_by: bf +creation_date: 2012-01-03T11:17:31Z + +[Term] +id: GO:0039534 +name: negative regulation of MDA-5 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA." [GOC:bf, GOC:jl] +synonym: "negative regulation of IFIH1 signaling pathway" EXACT [HGNC:18873] +synonym: "negative regulation of MDA-5 signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of MDA5 signaling pathway" EXACT [PMID:17328678] +synonym: "negative regulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [HGNC:18873] +is_a: GO:0039532 ! negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +is_a: GO:0039533 ! regulation of MDA-5 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039530 ! MDA-5 signaling pathway +relationship: negatively_regulates GO:0039530 ! MDA-5 signaling pathway +created_by: bf +creation_date: 2012-01-03T11:21:20Z + +[Term] +id: GO:0039535 +name: regulation of RIG-I signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA." [GOC:bf, GOC:jl] +synonym: "regulation of DDX58 signaling pathway" EXACT [HGNC:19102] +synonym: "regulation of retinoic acid inducible gene I signaling pathway" EXACT [HGNC:19102] +synonym: "regulation of RIG-I signalling pathway" EXACT [GOC:mah] +is_a: GO:0039531 ! regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039529 ! RIG-I signaling pathway +relationship: regulates GO:0039529 ! RIG-I signaling pathway +created_by: bf +creation_date: 2012-01-03T11:24:29Z + +[Term] +id: GO:0039536 +name: negative regulation of RIG-I signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA." [GOC:bf, GOC:jl] +synonym: "negative regulation of DDX58 signaling pathway" EXACT [HGNC:19102] +synonym: "negative regulation of retinoic acid inducible gene I signaling pathway" EXACT [HGNC:19102] +synonym: "negative regulation of RIG-I signalling pathway" EXACT [GOC:mah] +is_a: GO:0039532 ! negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +is_a: GO:0039535 ! regulation of RIG-I signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039529 ! RIG-I signaling pathway +relationship: negatively_regulates GO:0039529 ! RIG-I signaling pathway +created_by: bf +creation_date: 2012-01-03T11:27:51Z + +[Term] +id: GO:0039537 +name: suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response." [GOC:bf, GOC:jl] +synonym: "suppression by virus of host cytoplasmic pattern recognition receptor signaling pathway in response to virus" EXACT [GOC:bf] +synonym: "suppression by virus of host RIG-I-like receptor (RLR) signaling pathway" RELATED [GOC:bf] +synonym: "suppression by virus of host RIG-I/MDA5 signaling pathway" RELATED [GOC:bf] +synonym: "suppression by virus of host RIG-like helicase signaling pathway" RELATED [GOC:bf] +synonym: "suppression by virus of host RIG-like receptor signaling pathway" RELATED [GOC:bf] +synonym: "suppression by virus of host RLR signaling pathway" RELATED [GOC:bf] +synonym: "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0075111 ! suppression by symbiont of host receptor-mediated signal transduction +created_by: bf +creation_date: 2012-01-03T11:47:05Z + +[Term] +id: GO:0039538 +name: suppression by virus of host RIG-I signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response." [GOC:bf, GOC:jl] +synonym: "inhibition by virus of host RIG-I signaling" EXACT [GOC:bf] +synonym: "suppression by virus of host DDX58 signaling pathway" EXACT [GOC:bf] +synonym: "suppression by virus of host RIG-I signalling pathway" EXACT [GOC:mah] +is_a: GO:0039537 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway +created_by: bf +creation_date: 2012-01-03T11:50:17Z + +[Term] +id: GO:0039539 +name: suppression by virus of host MDA-5 signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response." [GOC:bf, GOC:jl] +synonym: "inhibition by virus of host MDA-5 signaling" EXACT [GOC:bf] +synonym: "suppression by virus of host IFIH1 signaling pathway" EXACT [GOC:bf] +synonym: "suppression by virus of host MDA-5 signalling pathway" EXACT [GOC:mah] +is_a: GO:0039537 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway +created_by: bf +creation_date: 2012-01-03T11:51:36Z + +[Term] +id: GO:0039540 +name: suppression by virus of host RIG-I activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1088, VZ:856] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response initiated by host RIG-I, either by binding and inhibiting host RIG-I directly, or by interfering with other processes so that RIG-I is unable to carry out its normal function (e.g. by processing viral RNA so it cannot be recognized by RIG-I, or by promoting the degradation of RIG-I). +synonym: "inhibition by virus of host DDX58 activity" EXACT [GOC:sp] +synonym: "inhibition by virus of host RIG-I" RELATED [GOC:bf] +synonym: "inhibition of host DDX58/RIG-I by virus" EXACT [UniProtKB-KW:KW-1088] +xref: VZ:856 "Inhibition of host RIG-I by virus" +is_a: GO:0039509 ! suppression by virus of host pattern recognition receptor activity +is_a: GO:0039538 ! suppression by virus of host RIG-I signaling pathway +created_by: bf +creation_date: 2012-01-18T02:24:20Z + +[Term] +id: GO:0039541 +name: obsolete suppression by virus of host RIG-I via RIG-I binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by interacting selectively and non-covalently with RIG-I itself." [PMID:19193793, PMID:20007272, VZ:856] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of host DDX58:MAVS binding" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-19T02:14:20Z + +[Term] +id: GO:0039542 +name: obsolete suppression by virus of host RIG-I K63-linked ubiquitination +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity." [PMID:19454348, PMID:21890623] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of host DDX58 K63-linked ubiquitination" EXACT [GOC:bf] +synonym: "inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination" BROAD [GOC:bf] +synonym: "inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I" EXACT [PMID:19454348] +is_obsolete: true +created_by: bf +creation_date: 2012-01-18T02:30:29Z + +[Term] +id: GO:0039543 +name: obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing +namespace: biological_process +def: "OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition." [PMID:18446221, VZ:856] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host RIG-I activity by inhibition of RNA binding" NARROW [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-18T02:30:29Z + +[Term] +id: GO:0039544 +name: obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction." [PMID:19628239] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "cleavage of RIG-I by viral proteinase" EXACT [PMID:19628239] +synonym: "inhibition by virus of host RIG-I activity by RIG-I proteolysis" RELATED [VZ:856] +is_obsolete: true +created_by: bf +creation_date: 2012-01-18T02:30:29Z + +[Term] +id: GO:0039545 +name: suppression by virus of host MAVS activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of MAVS (mitochondrial antiviral signaling protein), a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses." [UniProtKB-KW:KW-1097, VZ:704] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition of host MAVS by virus" EXACT [UniProtKB-KW:KW-1097, VZ:704] +synonym: "suppression by virus of host mitochondrial antiviral-signaling protein" EXACT [PR:000010210] +xref: VZ:704 "Inhibition of host MAVS by virus" +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039537 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway +created_by: bf +creation_date: 2012-01-19T02:37:20Z + +[Term] +id: GO:0039546 +name: obsolete suppression by virus of host MAVS activity by MAVS proteolysis +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling." [PMID:21436888, PMID:22238314] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "viral protease cleavage of MAVS" EXACT [PMID:22238314] +is_obsolete: true +created_by: bf +creation_date: 2012-01-19T02:49:44Z + +[Term] +id: GO:0039547 +name: suppression by virus of host TRAF activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components." [GOC:bf, UniProtKB-KW:KW-1110, VZ:715] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition of host TRAFs by virus" EXACT [UniProtKB-KW:KW-1110] +is_a: GO:0039507 ! suppression by virus of host molecular function +relationship: part_of GO:0039527 ! suppression by virus of host TRAF-mediated signal transduction +created_by: bf +creation_date: 2012-01-19T03:12:15Z + +[Term] +id: GO:0039548 +name: suppression by virus of host IRF3 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes." [PMID:21632562, UniProtKB-KW:KW-1092, VZ:757] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition of host IRF3 by virus" EXACT [UniProtKB-KW:KW-1092] +synonym: "Inhibition of IRF3-dependent antiviral response" BROAD [PMID:19125153] +synonym: "suppression by virus of host interferon regulatory factor 3" EXACT [PR:000002045] +xref: VZ:757 "Inhibition of host IRF3 by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2012-01-19T04:04:26Z + +[Term] +id: GO:0039549 +name: obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes." [PMID:11124948, PMID:12829834, PMID:20631144, PMID:9566918] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition of phosphorylation-induced activation of host IRF3" RELATED [PMID:11124948] +synonym: "inhibition of virus-induced IRF-3 phosphorylation" BROAD [PMID:12829834] +is_obsolete: true +created_by: bf +creation_date: 2012-01-19T04:27:06Z + +[Term] +id: GO:0039550 +name: obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites." [PMID:21632562] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of host IRF3-DNA binding" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-01-19T04:27:25Z + +[Term] +id: GO:0039551 +name: obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome." [VZ:757] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "promotion by virus of proteosome-dependent IRF3 degradation" EXACT [VZ:757] +is_obsolete: true +created_by: bf +creation_date: 2012-01-20T11:35:33Z + +[Term] +id: GO:0039552 +name: RIG-I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA." [GOC:bf, PMID:21233210] +synonym: "DDX58 binding" EXACT [GOC:sp] +synonym: "DDX58/RIG-I binding" EXACT [GOC:sp] +is_a: GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2012-01-19T02:14:20Z + +[Term] +id: GO:0039553 +name: suppression by virus of host chemokine activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1086, VZ:813] +synonym: "down-regulation by virus of host chemokine activity" EXACT [GOC:bf] +synonym: "downregulation by virus of host chemokine activity" EXACT [GOC:bf] +synonym: "inhibition by virus of host chemokine activity" NARROW [GOC:bf] +synonym: "inhibition of host chemokines by virus" NARROW [UniProtKB-KW:KW-1086] +synonym: "negative regulation by virus of host chemokine activity" EXACT [GOC:bf] +xref: VZ:813 "Inhibition of host chemokines by virus" +is_a: GO:0039518 ! suppression by virus of host cytokine activity +created_by: bf +creation_date: 2012-02-28T01:29:55Z + +[Term] +id: GO:0039554 +name: suppression by virus of host MDA-5 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." [UniProtKB-KW:KW-1089, VZ:603] +synonym: "inhibition of host IFIH1/MDA5 by virus" RELATED [UniProtKB-KW:KW-1089] +synonym: "Inhibition of host MDA5 by virus" EXACT [VZ:603] +xref: VZ:603 "Inhibition of host MDA5 by virus" +is_a: GO:0039509 ! suppression by virus of host pattern recognition receptor activity +is_a: GO:0039539 ! suppression by virus of host MDA-5 signaling pathway +created_by: bf +creation_date: 2012-03-09T03:03:49Z + +[Term] +id: GO:0039555 +name: obsolete suppression by virus of host MDA-5 activity via MDA-5 binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by interacting selectively and non-covalently with MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector." [PMID:19019954, VZ:603] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host MDA5 activity by MDA-5 binding" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-03-09T04:06:46Z + +[Term] +id: GO:0039556 +name: MDA-5 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA." [PMID:19019954] +synonym: "MDA5 binding" EXACT [GOC:bf] +is_a: GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2012-03-09T04:12:33Z + +[Term] +id: GO:0039557 +name: suppression by virus of host IRF7 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes." [UniProtKB-KW:KW-1093, VZ:653] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition of host interferon regulatory factor-7 by virus" EXACT [VZ:653] +synonym: "inhibition of host IRF7 by virus" EXACT [UniProtKB-KW:KW-1093] +synonym: "suppression by virus of host interferon regulatory factor 7 activity" EXACT [PR:000002049] +xref: VZ:653 "Inhibition of host IRF7 by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2012-03-09T04:17:46Z + +[Term] +id: GO:0039558 +name: obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity." [PMID:18635538, PMID:19694547, VZ:653] +comment: The reason for obsoleting is that the term is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "promotion of IRF-7 SUMOylation" EXACT [PMID:19694547] +synonym: "suppression by virus of host interferon regulatory factor-7 activity by positive regulation of IRF7 sumoylation" RELATED [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-03-09T04:27:57Z + +[Term] +id: GO:0039559 +name: obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome." [PMID:17301153, VZ:653] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "promotion by virus of proteosome-dependent IRF7 degradation" EXACT [VZ:653] +is_obsolete: true +created_by: bf +creation_date: 2012-03-09T04:38:58Z + +[Term] +id: GO:0039560 +name: suppression by virus of host IRF9 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes." [UniProtKB-KW:KW-1094, VZ:683] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition of host interferon regulatory factor-9 by virus" EXACT [GOC:bf] +synonym: "inhibition of host IRF9 by virus" EXACT [UniProtKB-KW:KW-1094] +synonym: "suppression by virus of host interferon regulatory factor 9 activity" EXACT [PR:000002051] +xref: VZ:683 "Inhibition of host IRF9 by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2012-03-09T04:42:08Z + +[Term] +id: GO:0039561 +name: obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism." [PMID:19109390] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host IRF9 activity by nuclear localization of IRF9" RELATED [PMID:19109390] +synonym: "suppression of interferon signaling by nuclear accumulation of IRF9" RELATED [PMID:19109390] +is_obsolete: true +created_by: bf +creation_date: 2012-03-09T04:53:44Z + +[Term] +id: GO:0039562 +name: suppression by virus of host STAT activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT (signal transducer and activator of transcription) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes." [GOC:bf] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition by virus of host STAT activity" NARROW [GOC:bf] +synonym: "suppression by virus of host signal transducer and activator of transcription activity" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039514 ! suppression by virus of host JAK-STAT cascade +created_by: bf +creation_date: 2012-03-12T02:28:39Z + +[Term] +id: GO:0039563 +name: suppression by virus of host STAT1 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes." [UniProtKB-KW:KW-1105, VZ:282] +comment: This term is for annotation of viral proteins that counteract the host anti-viral innate immune response. +synonym: "inhibition by virus of host STAT1 activity" NARROW [GOC:bf] +synonym: "Inhibition of host STAT1 by virus" NARROW [VZ:282] +xref: VZ:282 "Inhibition of host STAT1 by virus" +is_a: GO:0039562 ! suppression by virus of host STAT activity +created_by: bf +creation_date: 2012-03-12T02:35:39Z + +[Term] +id: GO:0039564 +name: suppression by virus of host STAT2 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes." [UniProtKB-KW:KW-1106, VZ:257] +synonym: "inhibition by virus of host STAT2 activity" NARROW [GOC:bf] +synonym: "Inhibition of host STAT2 by virus" EXACT [VZ:257] +xref: VZ:257 "Inhibition of host STAT2 by virus" +is_a: GO:0039562 ! suppression by virus of host STAT activity +created_by: bf +creation_date: 2012-03-12T02:52:34Z + +[Term] +id: GO:0039565 +name: obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome." [PMID:15280488, PMID:16227264, VZ:282] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "promotion by virus of proteosome-dependent STAT1 degradation" EXACT [] +synonym: "suppression by virus of host STAT1 activity by positive promotion of STAT1 proteasome-mediated degradation" EXACT [GOC:bf] +synonym: "targeting STAT1 for proteasome-mediated degradation" EXACT [VZ:282] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T02:57:36Z + +[Term] +id: GO:0039566 +name: obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1 +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation." [PMID:11238845, PMID:21362620, VZ:282] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1" EXACT [GOC:bf] +synonym: "viral tyrosine phosphatase activity involved in suppression of host STAT1" RELATED [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:08:32Z + +[Term] +id: GO:0039567 +name: obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes." [PMID:14557668, PMID:16254375, PMID:17287281] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "cytoplasmic sequestration of STAT1" BROAD [PMID:14557668] +synonym: "suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1" EXACT [PMID:14557668] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:24:36Z + +[Term] +id: GO:0039568 +name: obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus." [PMID:17287281] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition of DNA binding of STAT1" EXACT [PMID:17287281] +synonym: "suppression by virus of host STAT1 activity by negative regulation of DNA binding" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:31:58Z + +[Term] +id: GO:0039569 +name: obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome." [PMID:11336548, PMID:17251292, PMID:19279106, VZ:257] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "promotion by virus of proteosome-dependent STAT2 degradation" EXACT [] +synonym: "suppression by virus of host STAT2 activity by positive promotion of STAT2 proteasome-mediated degradation" EXACT [GOC:bf] +synonym: "targeting STAT2 for proteasome-mediated degradation" EXACT [VZ:257] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:43:44Z + +[Term] +id: GO:0039570 +name: obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes." [PMID:14557668] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "cytoplasmic sequestering of STAT2" EXACT [GOC:bf] +synonym: "cytoplasmic sequestration of STAT2" EXACT [PMID:14557668] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:46:49Z + +[Term] +id: GO:0039571 +name: obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation." [PMID:12804771] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of tyrosine phosphorylation of STAT1" RELATED [PMID:12804771] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:50:38Z + +[Term] +id: GO:0039572 +name: obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation." [PMID:12804771] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of tyrosine phosphorylation of STAT2" EXACT [PMID:12804771] +is_obsolete: true +created_by: bf +creation_date: 2012-03-12T04:53:50Z + +[Term] +id: GO:0039573 +name: suppression by virus of host complement activation +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase." [PMID:21191012, PMID:7745740, UniProtKB-KW:KW-1087, VZ:811] +synonym: "inhibition of host complement activation by virus" EXACT [GOC:bf] +synonym: "inhibition of host complement cascade by virus" EXACT [GOC:bf] +synonym: "inhibition of host complement factors by virus" BROAD [UniProtKB-KW:KW-1087] +xref: VZ:811 "Inhibition of host complement factors by virus" +is_a: GO:0030683 ! mitigation of host immune response by virus +is_a: GO:0045916 ! negative regulation of complement activation +is_a: GO:0075528 ! modulation by virus of host immune response +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0006956 ! complement activation +created_by: bf + +[Term] +id: GO:0039574 +name: suppression by virus of host TYK2 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity. TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits." [UniProtKB-KW:KW-1112, VZ:720] +synonym: "suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity" EXACT [PR:000016874] +xref: VZ:720 "Inhibition of host TYK2 by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039512 ! suppression by virus of host protein tyrosine kinase activity +created_by: bf + +[Term] +id: GO:0039575 +name: obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2." [PMID:10523853, PMID:16987978, PMID:19254804] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "inhibition by virus of host TYK2 activation" BROAD [GOC:bf, PMID:19254804] +synonym: "inhibition by virus of host TYK2 phosphorylation" EXACT [GOC:bf] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0039576 +name: suppression by virus of host JAK1 activity +namespace: biological_process +alt_id: GO:0039515 +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity. In the host, binding of a ligand to a receptor triggers activation of JAK proteins, which phosphorylate tyrosine residues on the receptor creating sites for STAT proteins to bind, which are in turn phosphorylated and activated by JAK proteins. By blocking JAK1 activity, many viruses block the host signal transduction pathway." [UniProtKB-KW:KW-1096, VZ:784] +synonym: "inhibition of host JAK activity by virus" NARROW [GOC:bf] +synonym: "negative regulation by virus of host JAK" EXACT [GOC:bf] +synonym: "negative regulation by virus of tyrosine phosphorylation of host STAT protein" NARROW [GOC:bf] +synonym: "suppression by virus of host janus kinase 1 activity" EXACT [PR:000009196] +synonym: "suppression by virus of tyrosine phosphorylation of host STAT protein" NARROW [] +synonym: "viral inhibition of tyrosine phosphorylation of host STAT protein" NARROW [GOC:bf] +xref: VZ:784 "Inhibition of host JAK1 by virus" +is_a: GO:0039512 ! suppression by virus of host protein tyrosine kinase activity +is_a: GO:0039514 ! suppression by virus of host JAK-STAT cascade +created_by: bf + +[Term] +id: GO:0039577 +name: obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1." [PMID:12620806] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +is_obsolete: true +created_by: bf + +[Term] +id: GO:0039578 +name: obsolete suppression by virus of host JAK1 activity via JAK1 binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive." [PMID:9448289] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +is_obsolete: true +created_by: bf + +[Term] +id: GO:0039579 +name: suppression by virus of host ISG15 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 activity. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives." [PMID:11157743, PMID:18604270, UniProtKB-KW:KW-1095, VZ:723] +xref: VZ:723 "Inhibition of host ISG15 by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: bf + +[Term] +id: GO:0039580 +name: suppression by virus of host PKR activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity. Activation of PKR involves dsRNA binding followed by autophosphorylation. Phosphorylated PKR can then phosphorylate downstream targets such as the translation initiation factor eIF2 to inhibit protein synthesis. Viruses encode a number of mechanisms to inhibit the host antiviral response via PKR, including direct interaction with PKR, promoting degradation of PKR or altering the subcellular location of PKR." [PMID:15207627, UniProtKB-KW:KW-1102, VZ:554] +synonym: "suppression by virus of host EIF2AK2 activity" EXACT [PR:000006959, UniProtKB-KW:KW-1102] +xref: VZ:554 "Inhibition of host PKR by virus" +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039584 ! suppression by virus of host protein kinase activity +created_by: bf + +[Term] +id: GO:0039581 +name: obsolete suppression by virus of host PKR activity via double-stranded RNA binding +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by interacting selectively and non-covalently with double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding." [PMID:7514679] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host PKR activity by binding to dsRNA" EXACT [GOC:bf] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0039582 +name: obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha)." [PMID:16987971] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "suppression by virus of host PKR activity by nuclear sequestration of PKR" EXACT [GOC:bf] +synonym: "suppression by virus of host PKR activity by positive regulation of PKR localization to nucleus" EXACT [GOC:bf] +synonym: "suppression by virus of host PKR activity by sequestering of PKR in nucleus" EXACT [PMID:16987971] +is_obsolete: true +created_by: bf + +[Term] +id: GO:0039583 +name: obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes." [PMID:19751406] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "downregulation of PKR by degradation through proteosome" EXACT [PMID:19751406] +synonym: "promotion by virus of proteosome-dependent PKR degradation" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-05-02T02:49:30Z + +[Term] +id: GO:0039584 +name: suppression by virus of host protein kinase activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity." [GOC:bf] +is_a: GO:0039513 ! suppression by virus of host catalytic activity +is_a: GO:0039613 ! suppression by virus of host protein phosphorylation +created_by: bf +creation_date: 2012-05-02T03:04:55Z + +[Term] +id: GO:0039585 +name: PKR signal transduction +namespace: biological_process +def: "A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR, an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation." [PMID:21204021, PMID:22102852, PMID:9843495, VZ:1576] +synonym: "PKR signaling pathway" EXACT [PMID:22102852] +synonym: "signaling through PKR" EXACT [GOC:bf] +is_a: GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2012-05-02T04:15:10Z + +[Term] +id: GO:0039586 +name: modulation by virus of host PP1 activity +namespace: biological_process +def: "The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response." [UniProtKB-KW:KW-1126, VZ:803] +synonym: "modulation of host PP1 activity by virus" EXACT [UniProtKB-KW:KW-1126] +synonym: "regulation by virus of host PP1 activity" EXACT [GOC:bf] +xref: VZ:803 "Modulation of host PP1 activity by virus" +is_a: GO:0039517 ! modulation by virus of host protein serine/threonine phosphatase activity +created_by: bf +creation_date: 2012-05-04T02:11:05Z + +[Term] +id: GO:0039587 +name: suppression by virus of host tetherin activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects." [PMID:22493439, UniProtKB-KW:KW-1084, VZ:665] +synonym: "inhibition of host BST2/Tetherin by virus" EXACT [UniProtKB-KW:KW-1084] +synonym: "suppression by virus of host BST-2 activity" EXACT [PMID:22493439] +xref: VZ:665 "Inhibition of host tetherin by virus" +is_a: GO:0039506 ! modulation by virus of host molecular function +created_by: bf +creation_date: 2012-05-04T02:33:29Z + +[Term] +id: GO:0039588 +name: suppression by virus of host antigen processing and presentation +namespace: biological_process +def: "Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex." [UniProtKB-KW:KW-1117, VZ:815] +synonym: "inhibition of host proteasome antigen processing by virus" EXACT [UniProtKB-KW:KW-1117] +xref: VZ:815 "Inhibition of host proteasome antigen processing by virus" +is_a: GO:0002578 ! negative regulation of antigen processing and presentation +is_a: GO:0030683 ! mitigation of host immune response by virus +is_a: GO:0075528 ! modulation by virus of host immune response +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0019882 ! antigen processing and presentation +created_by: bf +creation_date: 2012-05-04T04:34:52Z + +[Term] +id: GO:0039589 +name: obsolete suppression by virus of host TAP complex +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response." [PMID:16691491, UniProtKB-KW:KW-1107, VZ:817] +comment: This term was obsoleted because this type of process is now represented by the actual function inhibited. +synonym: "inhibition of host TAP by virus" EXACT [UniProtKB-KW:KW-1107] +xref: VZ:817 "Inhibition of host TAP by virus" +is_obsolete: true +consider: GO:0039588 +created_by: bf +creation_date: 2012-06-22T14:42:06Z + +[Term] +id: GO:0039591 +name: suppression by virus of host tapasin activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response." [UniProtKB-KW:KW-1108, VZ:818] +comment: Consider also annotating to 'tapasin binding ; GO:0046980'. +synonym: "inhibition of host tapasin by virus" EXACT [UniProtKB-KW:KW-1108] +synonym: "inhibition of host TAPBP by virus" EXACT [UniProtKB-KW:KW-1108] +synonym: "suppression by virus of host TAP binding protein" EXACT [HGNC:11566] +xref: VZ:818 "Inhibition of host tapasin by virus" +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0046776 ! suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I +created_by: bf +creation_date: 2012-06-25T01:27:48Z + +[Term] +id: GO:0039592 +name: suppression by virus of G2/M transition of host mitotic cell cycle +namespace: biological_process +def: "Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle." [UniProtKB-KW:KW-1079, VZ:876] +synonym: "host G2/M cell cycle arrest by virus" EXACT [UniProtKB-KW:KW-1079] +xref: VZ:876 "Host G2/M cell cycle arrest by virus" +is_a: GO:0060153 ! modulation by virus of host cell cycle +created_by: bf +creation_date: 2012-06-25T02:07:18Z + +[Term] +id: GO:0039593 +name: suppression by virus of host exit from mitosis +namespace: biological_process +def: "Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [UniProtKB-KW:KW-1098, VZ:877] +synonym: "inhibition of host mitotic exit by virus" EXACT [UniProtKB-KW:KW-1098, VZ:877] +xref: VZ:877 "Inhibition of host mitotic exit by virus" +is_a: GO:0060153 ! modulation by virus of host cell cycle +created_by: bf +creation_date: 2012-06-25T02:21:20Z + +[Term] +id: GO:0039594 +name: endoribonuclease activity involved in viral induction of host mRNA catabolic process +namespace: molecular_function +def: "Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA." [GOC:bf, PMID:22046136] +comment: GO:0039594 can be used to annotate a host or viral endoribonuclease activity that cleaves host mRNA in response to a viral infection. +is_a: GO:0004521 ! endoribonuclease activity +relationship: part_of GO:0039599 ! cleavage by virus of host mRNA +relationship: part_of GO:0039600 ! induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process +created_by: bf +creation_date: 2012-07-05T11:21:26Z + +[Term] +id: GO:0039595 +name: induction by virus of catabolism of host mRNA +namespace: biological_process +def: "The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA)." [GOC:bf, UniProtKB-KW:KW-1132] +synonym: "induction by virus of host mRNA catabolic process" EXACT [GOC:bf] +synonym: "induction of host mRNA decay" EXACT [VZ:901] +synonym: "promotion of host mRNA degradation" EXACT [] +synonym: "viral induction of host mRNA decay" EXACT [GOC:bf] +synonym: "virus-mediated mRNA decay" EXACT [VZ:901] +xref: VZ:901 "Virus-mediated host mRNA decay" +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0039656 ! modulation by virus of host gene expression +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +created_by: bf +creation_date: 2012-07-04T03:14:04Z + +[Term] +id: GO:0039596 +name: modulation by virus of host protein dephosphorylation +namespace: biological_process +def: "Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein." [GOC:bf] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0035304 ! regulation of protein dephosphorylation +created_by: bf +creation_date: 2012-07-19T11:46:23Z + +[Term] +id: GO:0039597 +name: induction by virus of host endoribonuclease activity +namespace: biological_process +def: "Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity." [PMID:22174690] +comment: GO:0039597 should be used to annotate viral proteins which utilize a host RNase to induce endonucleolytic cleavage of mRNAs (e.g. the NSP1 protein of SARS coronavirus). For viral proteins that have endoribonuclease activity themselves, consider instead annotating to: 'endoribonuclease activity involved in viral induction of host mRNA catabolic process ; GO:0039594'. +synonym: "viral induction of host RNAse activity" EXACT [GOC:bf] +is_a: GO:0039600 ! induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process +is_a: GO:0039712 ! induction by virus of host catalytic activity +created_by: bf +creation_date: 2012-07-04T04:36:49Z + +[Term] +id: GO:0039598 +name: obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process +namespace: biological_process +def: "OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA." [GOC:sp] +comment: This term was made obsolete because it is unclear what role the viral protein is playing in this process. and there is insufficient evidence to use this term for annotation. +synonym: "induction by virus of host nuclear poly(A)-dependent mRNA catabolic process" RELATED [GOC:vw] +synonym: "induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process" EXACT [] +synonym: "virus-mediated host mRNA decay by hyperadenylation" NARROW [GOC:sp] +is_obsolete: true +created_by: bf +creation_date: 2012-07-04T04:44:16Z + +[Term] +id: GO:0039599 +name: cleavage by virus of host mRNA +namespace: biological_process +def: "Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease." [PMID:22046136] +synonym: "host mRNA cleavage by viral endoribonuclease" EXACT [GOC:bf] +synonym: "viral endoribonuclease activity involved in degradation of host mRNA" RELATED [GOC:bf] +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0044033 ! multi-organism metabolic process +created_by: bf +creation_date: 2012-07-04T05:09:08Z + +[Term] +id: GO:0039600 +name: induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process +namespace: biological_process +def: "The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends." [GOC:bf, PMID:22174690] +comment: Some viruses utilize a host RNase to induce endonucleolytic cleavage of template mRNAs (e.g. the NSP1 protein of SARS coronavirus); for these consider instead annotating to the child term 'induction by virus of host endoribonuclease activity ; GO:0039597'. Other viral proteins act as endonucleases themselves to cleave mRNA and then rely on the host degradation machinery to clear the resulting fragments (e.g. gamma herpesvirus SOX protein); for these cases consider instead annotating to the child term 'endoribonuclease activity involved in viral induction of host mRNA catabolic process ; GO:0039594'. +synonym: "induction by virus of host endonucleolytic cleavage-dependent mRNA decay" EXACT [GOC:bf] +synonym: "induction by virus of host nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay" EXACT [GOC:bf] +is_a: GO:0039595 ! induction by virus of catabolism of host mRNA +created_by: bf +creation_date: 2012-07-04T05:23:43Z + +[Term] +id: GO:0039602 +name: suppression by virus of host transcription initiation from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:0039601 +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template." [UniProtKB-KW:KW-1111, VZ:904] +synonym: "inhibition of host transcription initiation by virus" EXACT [GOC:bf] +synonym: "suppression by virus of host DNA-dependent transcription, initiation" EXACT [] +xref: VZ:904 "Inhibition of host transcription initiation by virus" +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2012-07-05T03:29:34Z + +[Term] +id: GO:0039603 +name: obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter +namespace: molecular_function +def: "OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template." [GOC:vw, PMID:11968006] +comment: The reason for obsoletion is that the term is too specific, and the paper referenced in the term should instead be annotated to GO:0039602 ; suppression by virus of host transcription initiation from RNA polymerase II promoter. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14640 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2012-07-05T04:00:15Z + +[Term] +id: GO:0039604 +name: suppression by virus of host translation +namespace: biological_process +def: "Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA." [UniProtKB-KW:KW-1193, VZ:1579] +synonym: "host translation shutoff by virus" EXACT [UniProtKB-KW:KW-1193, VZ:1579] +synonym: "viral inhibition of cellular protein synthesis" EXACT [VZ:1579] +synonym: "viral shutoff of host protein synthesis" EXACT [PMID:8643618] +xref: VZ:1579 "Translation shutoff" +is_a: GO:0019057 ! modulation by virus of host translation +is_a: GO:0039657 ! suppression by virus of host gene expression +created_by: bf +creation_date: 2012-07-05T04:25:22Z + +[Term] +id: GO:0039605 +name: obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter +namespace: molecular_function +def: "OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template." [GOC:vw, PMID:18768974] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +is_obsolete: true +created_by: bf +creation_date: 2012-07-05T04:16:45Z + +[Term] +id: GO:0039606 +name: suppression by virus of host translation initiation +namespace: biological_process +def: "Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein." [GOC:bf] +is_a: GO:0039604 ! suppression by virus of host translation +created_by: bf +creation_date: 2012-07-05T04:44:10Z + +[Term] +id: GO:0039607 +name: obsolete proteolysis by virus of host translation initiation factor +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds." [PMID:18572216] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +synonym: "cleavage of host translation initiation factor by viral protease" EXACT [GOC:bf] +synonym: "cleavage of host translation initiation factor by virus" RELATED [GOC:sp] +synonym: "proteolytic cleavage by virus of host translation initiation factor" EXACT [GOC:bf] +synonym: "suppression by virus of host translation initiation factor activity by proteolysis" EXACT [GOC:bf] +is_obsolete: true +created_by: bf +creation_date: 2012-07-05T04:46:21Z + +[Term] +id: GO:0039608 +name: obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation +namespace: biological_process +def: "OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein." [PMID:12239292, PMID:8643618] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. +is_obsolete: true +created_by: bf +creation_date: 2012-07-06T10:30:57Z + +[Term] +id: GO:0039611 +name: suppression by virus of host translation initiation factor activity +namespace: biological_process +def: "Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor." [GOC:bf, UniProtKB-KW:KW-1075] +synonym: "inactivation of eIF2 activity" NARROW [PMID:12239292] +synonym: "inhibition of activity of host translation initiation factor" EXACT [PMID:12239292] +synonym: "Inhibition of host translation factors by virus" BROAD [UniProtKB-KW:KW-1075] +synonym: "suppression by virus of host EIF-4E activity" EXACT [GOC:bf] +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039606 ! suppression by virus of host translation initiation +created_by: bf +creation_date: 2012-07-06T10:27:16Z + +[Term] +id: GO:0039612 +name: modulation by virus of host protein phosphorylation +namespace: biological_process +def: "Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host." [GOC:bf] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0019054 ! modulation by virus of host cellular process +created_by: bf +creation_date: 2012-07-06T11:13:59Z + +[Term] +id: GO:0039613 +name: suppression by virus of host protein phosphorylation +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host." [GOC:bf] +synonym: "viral inhibition of host protein phosphorylation" EXACT [GOC:bf] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0039612 ! modulation by virus of host protein phosphorylation +created_by: bf +creation_date: 2012-07-06T11:15:56Z + +[Term] +id: GO:0039614 +name: induction by virus of host protein phosphorylation +namespace: biological_process +def: "Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host." [GOC:bf] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0039612 ! modulation by virus of host protein phosphorylation +created_by: bf +creation_date: 2012-07-06T11:15:56Z + +[Term] +id: GO:0039615 +name: T=1 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres." [UniProtKB-KW:KW-1140, VZ:1057] +xref: VZ:1057 "T=1 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T01:46:17Z + +[Term] +id: GO:0039616 +name: T=2 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers." [UniProtKB-KW:KW-1141, VZ:838] +comment: The T=2 symmetry is an non-official appellation; strictly speaking the capsid has a T=1 symmetry with each unit composed of a homodimer. +xref: VZ:838 "T=2 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:01:55Z + +[Term] +id: GO:0039617 +name: T=3 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres." [UniProtKB-KW:KW-1142, VZ:806] +xref: VZ:806 "T=3 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:07:40Z + +[Term] +id: GO:0039618 +name: T=pseudo3 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres." [UniProtKB-KW:KW-1143, VZ:809] +comment: T=pseudo3 capsids are not T=3 symmetry as described by Caspar and Klug (PMID:14019094) because the basic unit is composed of three different proteins. Since the three subunits are morphologically very similar, the structure is therefore a pseudo T=3. +xref: VZ:809 "T=pseudo3 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:10:02Z + +[Term] +id: GO:0039619 +name: T=4 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres." [UniProtKB-KW:KW-1144, VZ:808] +xref: VZ:808 "T=4 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:15:14Z + +[Term] +id: GO:0039620 +name: T=7 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres." [UniProtKB-KW:KW-1145, VZ:804] +comment: Spherical viruses with T numbers greater than or equal to 7 are skewed. They are therefore described as either right-handed (dextro) or left-handed (laevo). +xref: VZ:804 "T=7 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:16:40Z + +[Term] +id: GO:0039621 +name: T=13 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres." [UniProtKB-KW:KW-1146, VZ:260] +xref: VZ:260 "T=13 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:18:59Z + +[Term] +id: GO:0039622 +name: T=16 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres." [UniProtKB-KW:KW-1147, VZ:807] +xref: VZ:807 "T=16 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:20:23Z + +[Term] +id: GO:0039623 +name: T=25 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres." [UniProtKB-KW:KW-1148, VZ:810] +xref: VZ:810 "T=25 icosahedral capsid protein" +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T02:21:43Z + +[Term] +id: GO:0039624 +name: viral outer capsid +namespace: cellular_component +def: "The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions." [UniProtKB-KW:KW-1152] +synonym: "outer capsid" EXACT [GOC:bf] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T04:03:16Z + +[Term] +id: GO:0039625 +name: viral inner capsid +namespace: cellular_component +def: "The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions." [UniProtKB-KW:KW-1153] +synonym: "inner capsid" EXACT [GOC:bf] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T04:05:35Z + +[Term] +id: GO:0039626 +name: viral intermediate capsid +namespace: cellular_component +def: "The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions." [UniProtKB-KW:KW-1154] +synonym: "intermediate capsid" EXACT [GOC:bf] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-07-18T04:06:25Z + +[Term] +id: GO:0039627 +name: T=147 icosahedral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins." [GOC:plm, UniProtKB-KW:KW-0167] +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-08-03T16:18:49Z + +[Term] +id: GO:0039628 +name: T=169 icosahedral viral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins." [GOC:plm, UniProtKB-KW:KW-1150] +synonym: "T=169 icosahedral capsid" EXACT [GOC:bf] +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-08-03T16:27:55Z + +[Term] +id: GO:0039629 +name: T=219 icosahedral capsid +namespace: cellular_component +def: "The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins." [GOC:plm, UniProtKB-KW:KW-1151] +is_a: GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2012-08-03T16:29:00Z + +[Term] +id: GO:0039630 +name: RNA translocase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule." [GOC:bm, PMID:22713318] +comment: Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane. +is_a: GO:0008186 ! RNA-dependent ATPase activity +created_by: bf +creation_date: 2012-08-06T13:24:51Z + +[Term] +id: GO:0039631 +name: DNA translocase activity involved in viral DNA genome packaging +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid." [GOC:bm, PMID:17501915] +synonym: "viral DNA packaging activity" RELATED [GOC:bm] +synonym: "viral DNA packaging motor activity" RELATED [PMID:17501915] +is_a: GO:0015616 ! DNA translocase activity +intersection_of: GO:0015616 ! DNA translocase activity +intersection_of: part_of GO:0019073 ! viral DNA genome packaging +relationship: part_of GO:0019073 ! viral DNA genome packaging +created_by: bf +creation_date: 2012-08-07T11:17:07Z + +[Term] +id: GO:0039632 +name: RNA translocase activity involved in viral RNA genome packaging +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid." [GOC:bm, PMID:22297533] +synonym: "RNA packaging ATPase activity" EXACT [PMID:22297533] +synonym: "viral RNA packaging activity" RELATED [GOC:bm] +is_a: GO:0039630 ! RNA translocase activity +intersection_of: GO:0039630 ! RNA translocase activity +intersection_of: part_of GO:0019074 ! viral RNA genome packaging +relationship: part_of GO:0019074 ! viral RNA genome packaging +created_by: bf +creation_date: 2012-08-07T11:20:53Z + +[Term] +id: GO:0039633 +name: killing by virus of host cell +namespace: biological_process +def: "Any process mediated by a virus that results in the death of a cell in the host organism." [GOC:bf, GOC:bm, GOC:jl] +synonym: "killing by phage of host cells" NARROW [GOC:bm] +synonym: "killing by virus of host cells" EXACT [] +is_a: GO:0001907 ! killing by symbiont of host cells +created_by: bf +creation_date: 2012-08-10T14:44:40Z + +[Term] +id: GO:0039634 +name: killing by virus of host cell during superinfection exclusion +namespace: biological_process +def: "The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus." [GOC:bf, GOC:bm, GOC:jl, PMID:22398285] +synonym: "killing by virus of host cells during superinfection exclusion" EXACT [] +synonym: "killing by virus of host cells involved in superinfection exclusion" EXACT [GOC:bf] +synonym: "Rex exclusion" NARROW [] +is_a: GO:0009615 ! response to virus +is_a: GO:0039633 ! killing by virus of host cell +created_by: bf +creation_date: 2012-08-10T14:46:03Z + +[Term] +id: GO:0039635 +name: suppression by virus of host peptidoglycan biosynthetic process +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls." [GOC:bf, GOC:bm, GOC:jl] +synonym: "viral inhibition of host peptidoglycan biosynthesis" RELATED [GOC:bf] +is_a: GO:0039636 ! suppression by virus of host cell wall biogenesis +created_by: bf +creation_date: 2012-08-10T14:58:12Z + +[Term] +id: GO:0039636 +name: suppression by virus of host cell wall biogenesis +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts." [GOC:bf, GOC:bm, GOC:jl] +is_a: GO:0019054 ! modulation by virus of host cellular process +created_by: bf +creation_date: 2012-08-10T15:04:12Z + +[Term] +id: GO:0039637 +name: catabolism by virus of host DNA +namespace: biological_process +def: "The breakdown of host DNA, deoxyribonucleic acid, by a virus." [GOC:bf, GOC:bm, GOC:jl] +is_a: GO:0019048 ! modulation by virus of host process +created_by: bf +creation_date: 2012-08-10T15:59:22Z + +[Term] +id: GO:0039638 +name: lipopolysaccharide-mediated virion attachment to host cell +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface." [GOC:bf, GOC:bm, PMID:12837775] +synonym: "lipopolysaccharide binding involved in viral attachment to host cell" EXACT [GOC:bf, GOC:bm] +synonym: "LPS binding involved in viral attachment to host cell" EXACT [GOC:bf] +synonym: "virion attachment, binding to host lipopolysaccharide" EXACT [GOC:bf, GOC:jl] +is_a: GO:0019062 ! virion attachment to host cell +relationship: has_part GO:0001530 ! lipopolysaccharide binding +created_by: bf +creation_date: 2012-08-17T10:13:06Z + +[Term] +id: GO:0039639 +name: suppression by virus of host cell lysis in response to superinfection +namespace: biological_process +def: "The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus." [GOC:bm, GOC:jl, PMID:22389108, PMID:9560373] +synonym: "lysis inhibition" BROAD [GOC:bm, PMID:22389108] +synonym: "suppression by virus of host cell lysis in response to superinfecting virus" EXACT [GOC:bf] +is_a: GO:0001899 ! negative regulation of cytolysis by symbiont of host cells +is_a: GO:0098586 ! cellular response to virus +created_by: bf +creation_date: 2012-08-17T10:42:27Z + +[Term] +id: GO:0039640 +name: viral release by cytolysis via suppression of host peptidoglycan biosynthetic process +namespace: biological_process +def: "The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls." [GOC:bf, GOC:bm, PMID:28894177] +synonym: "cytolysis by virus via suppression of host peptidoglycan biosynthetic process" RELATED [] +synonym: "viral exit by cytolysis via suppression of host peptidoglycan biosynthetic process" EXACT [] +is_a: GO:0044659 ! viral release from host cell by cytolysis +relationship: has_part GO:0039635 ! suppression by virus of host peptidoglycan biosynthetic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18852 xsd:anyURI +created_by: bf +creation_date: 2012-08-17T10:54:55Z + +[Term] +id: GO:0039641 +name: viral inner membrane +namespace: cellular_component +def: "The lipid bilayer of a virion contained inside the protein capsid." [GOC:bm, PMID:15331712] +synonym: "virion inner membrane" EXACT [GOC:bf, GOC:bm, GOC:jl] +is_a: GO:0036338 ! viral membrane +created_by: bf +creation_date: 2012-09-07T13:29:48Z + +[Term] +id: GO:0039642 +name: virion nucleoid +namespace: cellular_component +def: "The region of a virion in which the nucleic acid is confined." [GOC:bm, PMID:14291596] +is_a: GO:0009295 ! nucleoid +is_a: GO:0044423 ! virion part +intersection_of: GO:0009295 ! nucleoid +intersection_of: part_of GO:0019012 ! virion +created_by: bf +creation_date: 2012-09-07T14:14:52Z + +[Term] +id: GO:0039643 +name: host cell viral nucleoid +namespace: cellular_component +def: "The region of a host cell that contains the viral genome." [GOC:bf, GOC:bm, GOC:jl] +comment: To annotate the region of the complete virus particle in which the viral genome is contained, instead use 'virion nucleoid ; GO:0039642'. +is_a: GO:0033646 ! host intracellular part +created_by: bf +creation_date: 2012-09-07T15:41:18Z + +[Term] +id: GO:0039644 +name: suppression by virus of host NF-kappaB transcription factor activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity." [UniProtKB-KW:KW-1100, VZ:695] +synonym: "inhibition of host NF-kappa-B by virus" EXACT [UniProtKB-KW:KW-1100, VZ:695] +xref: VZ:695 "Inhibition of host NF-kappa-B by virus" +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039653 ! suppression by virus of host transcription +created_by: bf +creation_date: 2012-10-09T15:04:27Z + +[Term] +id: GO:0039645 +name: modulation by virus of host G1/S transition checkpoint +namespace: biological_process +def: "Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint." [UniProtKB-KW:KW-1078] +synonym: "G1/S host cell cycle checkpoint dysregulation by virus" EXACT [UniProtKB-KW:KW-1078, VZ:880] +xref: VZ:880 "G1/S host cell cycle checkpoint dysregulation by virus" +is_a: GO:0060153 ! modulation by virus of host cell cycle +created_by: bf +creation_date: 2012-10-09T15:08:57Z + +[Term] +id: GO:0039646 +name: modulation by virus of host G0/G1 transition checkpoint +namespace: biological_process +def: "Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint." [UniProtKB-KW:KW-1077] +synonym: "G0/G1 host cell cycle checkpoint dysregulation by virus" EXACT [UniProtKB-KW:KW-1077, VZ:881] +xref: VZ:881 "G0/G1 host cell cycle checkpoint dysregulation by virus" +is_a: GO:0060153 ! modulation by virus of host cell cycle +created_by: bf +creation_date: 2012-10-09T15:11:22Z + +[Term] +id: GO:0039647 +name: suppression by virus of host poly(A)-binding protein activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation." [UniProtKB-KW:KW-1101] +synonym: "inhibition of host poly(A)-binding protein by virus" EXACT [UniProtKB-KW:KW-1101] +synonym: "suppression by virus of host PABP activity" EXACT [Wikipedia:Poly(A)-binding_protein] +is_a: GO:0039507 ! suppression by virus of host molecular function +is_a: GO:0039604 ! suppression by virus of host translation +created_by: bf +creation_date: 2012-10-09T15:14:07Z + +[Term] +id: GO:0039648 +name: modulation by virus of host protein ubiquitination +namespace: biological_process +def: "Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein." [UniProtKB-KW:KW-1130] +synonym: "modulation of host ubiquitin pathway by virus" RELATED [UniProtKB-KW:KW-1130] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0031396 ! regulation of protein ubiquitination +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0016567 ! protein ubiquitination +created_by: bf +creation_date: 2012-10-09T15:20:47Z + +[Term] +id: GO:0039649 +name: modulation by virus of host ubiquitin-protein ligase activity +namespace: biological_process +def: "The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine." [UniProtKB-KW:KW-1123] +synonym: "modulation of host E3 ubiquitin ligases by virus" NARROW [UniProtKB-KW:KW-1123] +is_a: GO:0039516 ! modulation by virus of host catalytic activity +is_a: GO:0039648 ! modulation by virus of host protein ubiquitination +is_a: GO:1904666 ! regulation of ubiquitin protein ligase activity +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0061630 ! ubiquitin protein ligase activity +created_by: bf +creation_date: 2012-10-09T15:26:56Z + +[Term] +id: GO:0039650 +name: suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process." [UniProtKB-KW:KW-1085, VZ:912] +synonym: "inhibition of host caspases by virus" NARROW [UniProtKB-KW:KW-1085, VZ:912] +is_a: GO:0019050 ! suppression by virus of host apoptotic process +is_a: GO:0039513 ! suppression by virus of host catalytic activity +created_by: bf +creation_date: 2012-10-09T15:30:48Z + +[Term] +id: GO:0039651 +name: induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +def: "Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process." [GOC:mtg_apoptosis, UniProtKB-KW:KW-1073] +synonym: "activation of host caspases by virus" NARROW [UniProtKB-KW:KW-1073] +synonym: "induction by virus of host caspase activity" NARROW [GOC:bf, GOC:jl] +is_a: GO:0019051 ! induction by virus of host apoptotic process +is_a: GO:0039712 ! induction by virus of host catalytic activity +created_by: bf +creation_date: 2012-10-09T15:44:29Z + +[Term] +id: GO:0039652 +name: activation by virus of host NF-kappaB transcription factor activity +namespace: biological_process +def: "Any process in which a virus starts, promotes, or enhances the activity of the host transcription factor NF-kappaB." [UniProtKB-KW:KW-1074] +synonym: "activation of host NF-kappa-B by virus" EXACT [UniProtKB-KW:KW-1074] +xref: VZ:841 "Activation of host NF-kappa-B by virus" +is_a: GO:0019056 ! modulation by virus of host transcription +is_a: GO:0039506 ! modulation by virus of host molecular function +created_by: bf +creation_date: 2012-10-11T16:04:31Z + +[Term] +id: GO:0039653 +name: suppression by virus of host transcription +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors." [UniProtKB-KW:KW-1191, VZ:1577] +synonym: "host transcription shutoff by virus" NARROW [UniProtKB-KW:KW-1191, VZ:1577] +synonym: "suppression by virus of host DNA-dependent transcription" EXACT [GOC:bf] +xref: VZ:1577 "Host transcription shutoff by virus" +is_a: GO:0019056 ! modulation by virus of host transcription +is_a: GO:0039657 ! suppression by virus of host gene expression +created_by: bf +creation_date: 2012-10-11T16:11:17Z + +[Term] +id: GO:0039654 +name: fusion of virus membrane with host endosome membrane +namespace: biological_process +alt_id: GO:0075501 +alt_id: GO:0075517 +def: "Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell." [GOC:bf, UniProtKB-KW:KW-1170, VZ:992] +synonym: "fusion of virus membrane with host endosomal membrane" EXACT [UniProtKB-KW:KW-1170, VZ:992] +synonym: "viral entry into host cell via caveolae-mediated endocytosis followed by membrane fusion with the endosome membrane" NARROW [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via caveolin-mediated endocytosis followed by membrane fusion with the endosome membrane" NARROW [] +synonym: "viral entry into host cell via clathrin-mediated endocytosis followed by membrane fusion with the endosome membrane" NARROW [] +synonym: "viral entry into host cell via endocytosis followed by membrane fusion with host endosome" RELATED [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via endocytosis followed by membrane fusion with the endosome membrane" RELATED [GOC:bf, GOC:jl] +synonym: "viral penetration via endocytosis followed by caveolae-mediated membrane fusion with the endosome membrane" NARROW [] +synonym: "viral penetration via endocytosis followed by clathrin-mediated membrane fusion with the endosome membrane" NARROW [] +xref: VZ:992 "Fusion of virus membrane with host endosomal membrane" +is_a: GO:0039663 ! membrane fusion involved in viral entry into host cell +created_by: bf +creation_date: 2013-06-20T14:24:05Z + +[Term] +id: GO:0039655 +name: obsolete transport of virus in host, cell to cell via plasmodesmata +namespace: biological_process +def: "OBSOLETE. The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell." [UniProtKB-KW:KW-0916, VZ:1018] +synonym: "spread of virus in host, cell to cell via plasmodesmata" RELATED [GOC:bf, GOC:jl] +synonym: "viral movement protein" RELATED [VZ:1018] +xref: VZ:1018 "Viral movement protein" +is_obsolete: true +created_by: bf +creation_date: 2013-06-20T14:47:50Z + +[Term] +id: GO:0039656 +name: modulation by virus of host gene expression +namespace: biological_process +def: "The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:bf] +synonym: "regulation by virus of host gene expression" RELATED [GOC:bf] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0019048 ! modulation by virus of host process +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: regulates GO:0010467 ! gene expression +created_by: bf +creation_date: 2013-06-20T15:28:26Z + +[Term] +id: GO:0039657 +name: suppression by virus of host gene expression +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [UniProtKB-KW:KW-1190, VZ:1582] +synonym: "host gene expression shutoff by virus" EXACT [UniProtKB-KW:KW-1190, VZ:1582] +xref: VZ:1582 "Host gene expression shutoff by virus" +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0039656 ! modulation by virus of host gene expression +created_by: bf +creation_date: 2013-06-20T15:29:55Z + +[Term] +id: GO:0039658 +name: TBK1-IKKE-DDX3 complex +namespace: cellular_component +def: "A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3." [PMID:18636090, VZ:719] +synonym: "TBK1-IKBKE-DDX3 complex" EXACT [VZ:719] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2013-07-03T16:59:27Z + +[Term] +id: GO:0039659 +name: obsolete suppression by virus of host TBK1-IKBKE-DDX3 complex activity +namespace: biological_process +def: "OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex." [VZ:719] +comment: The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. See also: suppression by virus of host TBK1 activity; GO:0039723, and suppression by virus of host IKBKE activity; GO:0039724. +synonym: "inhibition of host TBK1-IKBKE-DDX3 complex by virus" EXACT [VZ:719] +synonym: "suppression by virus of host TBK1-IKKE-DDX3 complex activity" EXACT [] +xref: VZ:719 "Inhibition of host TBK1-IKBKE-DDX3 complex by virus" +is_obsolete: true +created_by: bf +creation_date: 2013-07-15T15:10:39Z + +[Term] +id: GO:0039660 +name: structural constituent of virion +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a virion." [GOC:bf, GOC:jl] +synonym: "viral matrix protein" NARROW [UniProtKB-KW:KW-0468] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0019012 ! virion +relationship: occurs_in GO:0019012 ! virion +property_value: RO:0002161 NCBITaxon:131567 +created_by: bf +creation_date: 2013-07-22T16:43:41Z + +[Term] +id: GO:0039661 +name: host organelle outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell." [GOC:bf, GOC:ch] +is_a: GO:0044384 ! host outer membrane +created_by: bf +creation_date: 2013-08-25T10:44:43Z + +[Term] +id: GO:0039662 +name: host cell outer membrane +namespace: cellular_component +def: "A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell." [GOC:bf, GOC:ch] +synonym: "host cell envelope outer membrane" EXACT [GOC:bf, GOC:ch] +synonym: "outer membrane of host cell" EXACT [GOC:bf, GOC:ch] +is_a: GO:0044384 ! host outer membrane +relationship: part_of GO:0044230 ! host cell envelope +created_by: bf +creation_date: 2013-08-25T10:48:41Z + +[Term] +id: GO:0039663 +name: membrane fusion involved in viral entry into host cell +namespace: biological_process +def: "Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1168] +synonym: "fusion of virus membrane with host membrane" RELATED [UniProtKB-KW:KW-1168] +synonym: "fusion of virus membrane with host membrane during viral entry" RELATED [UniProtKB-KW:KW-1168] +synonym: "viral entry into host cell via membrane fusion" RELATED [GOC:bf, GOC:jl] +is_a: GO:0044800 ! multi-organism membrane fusion +intersection_of: GO:0061025 ! membrane fusion +intersection_of: part_of GO:0046718 ! viral entry into host cell +relationship: part_of GO:0046718 ! viral entry into host cell +created_by: bf +creation_date: 2013-08-29T10:15:11Z + +[Term] +id: GO:0039664 +name: lysis of host organelle involved in viral entry into host cell +namespace: biological_process +def: "The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1174, VZ:984] +synonym: "viral entry into host cell via endosome membrane lysis" NARROW [VZ:984] +synonym: "viral entry into host cell via lysis of host organelle membrane" RELATED [GOC:bf, GOC:jl] +synonym: "viral membrane-lytic protein" RELATED [UniProtKB-KW:KW-1174] +synonym: "viral penetration via lysis of host organellar membrane" EXACT [UniProtKB-KW:KW-984] +xref: VZ:984 "Viral penetration via lysis of host organellar membrane" +is_a: GO:0016032 ! viral process +relationship: has_part GO:0044662 ! disruption by virus of host cell membrane +relationship: part_of GO:0046718 ! viral entry into host cell +created_by: bf +creation_date: 2013-08-29T11:30:18Z + +[Term] +id: GO:0039665 +name: permeabilization of host organelle membrane involved in viral entry into host cell +namespace: biological_process +def: "Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1173, VZ:985] +synonym: "viral entry into host cell via permeabilization of host organelle membrane" RELATED [GOC:bf, GOC:jl] +synonym: "viral membrane-penetration protein" RELATED [UniProtKB-KW:KW-1173] +synonym: "viral penetration via host endosomal membrane disruption by virus" EXACT [UniProtKB-KW:KW-1173] +synonym: "viral penetration via perforation of host organellar membrane by virus" EXACT [UniProtKB-KW:KW-1173] +synonym: "viral penetration via permeabilization of host organellar membrane" EXACT [UniProtKB-KW:KW-1173, VZ:985] +xref: VZ:985 "Viral penetration via permeabilization of host organellar membrane" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0140267 ! viral entry via permeabilization of host membrane +created_by: bf +creation_date: 2013-08-29T11:57:21Z + +[Term] +id: GO:0039666 +name: virion attachment to host cell pilus +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side." [UniProtKB-KW:KW-1175, VZ:981] +synonym: "pilus-adsorption protein" EXACT [PMID:16298408] +synonym: "pilus-mediated viral adsorption onto host cell" RELATED [UniProtKB-KW:KW-1175, VZ:981] +synonym: "pilus-mediated viral attachment to host cell" RELATED [GOC:bf, GOC:jl] +synonym: "viral attachment to host cell pilus" RELATED [GOC:bf, GOC:jl] +xref: VZ:981 "Pilus-mediated viral adsorption onto host cell" +is_a: GO:0019062 ! virion attachment to host cell +created_by: bf +creation_date: 2013-08-29T13:31:10Z + +[Term] +id: GO:0039667 +name: viral entry into host cell via pilus retraction +namespace: biological_process +def: "The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus." [GOC:bf, GOC:jl, VZ:981] +comment: This method of entry into the cell differs between viruses; filamentous bacteriophages have rod-shaped virions which attach to the tip of the pilus; after retraction of the pilus with the virion attached, the genome can enter the host cell through the pilus basal pore. For icosahedral viruses, retraction of the pilus brings the virus in contact with the cell membrane and the genome can enter the cell via membrane fusion or genome injection. In GO, viral entry begins after viral attachment; for pilus-attachment proteins see instead: viral attachment to host cell pilus ; GO:0039666. +is_a: GO:0046718 ! viral entry into host cell +relationship: has_part GO:0043108 ! pilus retraction +relationship: has_part GO:0046794 ! transport of virus +created_by: bf +creation_date: 2013-09-04T14:32:19Z + +[Term] +id: GO:0039668 +name: viral entry into host cell via pilus basal pore +namespace: biological_process +def: "The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way." [GOC:bf, GOC:jl] +synonym: "filamentous viral entry into host cell via pilus retraction" NARROW [GOC:bf, GOC:jl, VZ:981] +is_a: GO:0039667 ! viral entry into host cell via pilus retraction +created_by: bf +creation_date: 2013-09-04T14:33:18Z + +[Term] +id: GO:0039669 +name: viral entry into host cell via pilus retraction and membrane fusion +namespace: biological_process +def: "The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane." [GOC:bf, GOC:jl, PMID:20427561, VZ:981] +comment: For annotation of viral pilus-binding proteins, see also 'viral attachment to host cell pilus ; GO:0039666'. +is_a: GO:0039667 ! viral entry into host cell via pilus retraction +relationship: has_part GO:0019064 ! fusion of virus membrane with host plasma membrane +created_by: bf +creation_date: 2013-09-04T14:35:44Z + +[Term] +id: GO:0039670 +name: viral capsid, turret +namespace: cellular_component +def: "A turret-like appendage formed at the vertices of an icosahedral capsid." [GOC:jh2, PMID:20592081] +is_a: GO:0098021 ! viral capsid, decoration +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bf +creation_date: 2013-09-25T10:08:14Z + +[Term] +id: GO:0039671 +name: evasion by virus of host natural killer cell activity +namespace: biological_process +def: "Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells." [GOC:bf, GOC:jl, PMID:15640804, PMID:18688275, UniProtKB-KW:KW-1131] +synonym: "evasion by virus of host natural killer cell response" EXACT [] +synonym: "evasion by virus of host NK cell killing" EXACT [GOC:bf] +synonym: "modulation of host NK-cell activity by virus" RELATED [UniProtKB-KW:KW-1131] +synonym: "protection by virus against host NK cell cytotoxicity" EXACT [PMID:12782710] +synonym: "suppression by virus of host natural killer cell function" EXACT [PMID:15640804] +synonym: "viral immunoevasion of host NK cell" EXACT [GOC:bf] +is_a: GO:0030683 ! mitigation of host immune response by virus +created_by: bf +creation_date: 2013-09-25T11:04:53Z + +[Term] +id: GO:0039672 +name: suppression by virus of host natural killer cell activation +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host." [GOC:bf, GOC:jl] +synonym: "suppression by virus of host NK-cell activation" EXACT [GOC:bf, GOC:jl] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0032815 ! negative regulation of natural killer cell activation +is_a: GO:0039671 ! evasion by virus of host natural killer cell activity +created_by: bf +creation_date: 2013-09-25T11:08:19Z + +[Term] +id: GO:0039673 +name: evasion by virus of host dendritic cell activity +namespace: biological_process +def: "Any process by which a virus avoids the effects mediated by the host organism's dendritic cells." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1118] +synonym: "evasion by virus of host dendritic cell response" EXACT [] +synonym: "impairing dendritic cell function by virus" EXACT [UniProtKB-KW:KW-1118] +synonym: "modulation of host dendritic cell activity by virus" BROAD [UniProtKB-KW:KW-1118] +is_a: GO:0030683 ! mitigation of host immune response by virus +created_by: bf +creation_date: 2013-09-25T11:18:51Z + +[Term] +id: GO:0039674 +name: exit of virus from host cell nucleus +namespace: biological_process +def: "The directed movement of the viral genome or a viral particle out of the host cell nucleus." [VZ:2177] +xref: VZ:2177 "Nuclear exit of viral genome" +is_a: GO:0075733 ! intracellular transport of virus +created_by: bf +creation_date: 2013-09-25T13:59:41Z + +[Term] +id: GO:0039675 +name: exit of virus from host cell nucleus through nuclear pore +namespace: biological_process +def: "The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore." [PMID:12921991, VZ:1953] +synonym: "exit of virus from host cell nucleus through nuclear pore complex" EXACT [] +synonym: "nuclear pore exit of virus" EXACT [VZ:1953] +synonym: "viral enome export through nuclear pore" EXACT [VZ:1953] +xref: VZ:1953 "Genome export through nuclear pore" +is_a: GO:0039674 ! exit of virus from host cell nucleus +created_by: bf +creation_date: 2013-09-25T14:10:03Z + +[Term] +id: GO:0039677 +name: exit of virus from host cell nucleus via nuclear envelope disassembly +namespace: biological_process +def: "The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus." [VZ:2176] +synonym: "exit of virus from host cell nucleus via nuclear envelope breakdown" EXACT [VZ:2176] +xref: VZ:2176 "Nuclear envelope breakdown" +is_a: GO:0039674 ! exit of virus from host cell nucleus +relationship: has_part GO:0051081 ! nuclear envelope disassembly +created_by: bf +creation_date: 2013-09-25T14:10:03Z + +[Term] +id: GO:0039678 +name: viral genome ejection through host cell envelope +namespace: biological_process +def: "Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm." [GOC:ch, PMID:23385786, UniProtKB-KW:KW-1171] +comment: When a pore-forming protein is involved, see also 'pore-mediated entry of viral genome into host cell ; GO:0044694'. +synonym: "phage genome ejection" NARROW [PMID:23385786] +synonym: "viral genome injection through bacterial membranes" NARROW [UniProtKB-KW:KW-1171] +is_a: GO:0046718 ! viral entry into host cell +created_by: bf +creation_date: 2013-09-26T11:56:48Z + +[Term] +id: GO:0039679 +name: viral occlusion body +namespace: cellular_component +def: "A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host." [UniProtKB-KW:KW-0842, VZ:1949] +xref: VZ:1949 "Occlusion bodies" +is_a: GO:0140220 ! pathogen-containing vacuole +relationship: has_part GO:0019012 ! virion +property_value: RO:0002161 NCBITaxon:131567 +created_by: bf +creation_date: 2013-09-26T14:17:10Z + +[Term] +id: GO:0039680 +name: actin-dependent intracellular transport of virus towards nucleus +namespace: biological_process +def: "The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments." [UniProtKB-KW:KW-1178, VZ:991] +synonym: "actin-dependent intracellular transport of viral material towards nucleus" EXACT [] +synonym: "actin-dependent inwards viral transport" EXACT [VZ:991] +xref: VZ:991 "Actin-dependent inwards viral transport" +is_a: GO:0075520 ! actin-dependent intracellular transport of virus +is_a: GO:0075606 ! transport of viral material towards nucleus +created_by: bf +creation_date: 2013-10-10T11:24:56Z + +[Term] +id: GO:0039682 +name: rolling circle viral DNA replication +namespace: biological_process +def: "A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA." [GOC:bf, GOC:jl, VZ:915, Wikipedia:Rolling_circle_replication] +is_a: GO:0039687 ! viral DNA strand displacement replication +created_by: bf +creation_date: 2013-10-17T14:13:51Z + +[Term] +id: GO:0039683 +name: rolling circle double-stranded viral DNA replication +namespace: biological_process +def: "A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome." [GOC:bf, GOC:jl, VZ:2676] +synonym: "dsDNA rolling circle replication" EXACT [VZ:2676] +xref: VZ:2676 "dsDNA rolling circle replication" +is_a: GO:0039682 ! rolling circle viral DNA replication +created_by: bf +creation_date: 2013-10-17T14:15:04Z + +[Term] +id: GO:0039684 +name: rolling circle single-stranded viral DNA replication +namespace: biological_process +def: "A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome." [GOC:bf, GOC:jl, VZ:1941] +synonym: "ssDNA rolling circle replication" EXACT [VZ:1941] +xref: VZ:1941 "ssDNA Rolling circle" +is_a: GO:0039682 ! rolling circle viral DNA replication +created_by: bf +creation_date: 2013-10-17T14:15:48Z + +[Term] +id: GO:0039685 +name: rolling hairpin viral DNA replication +namespace: biological_process +def: "A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA." [GOC:bf, GOC:jl, VZ:2656] +synonym: "ssDNA rolling hairpin viral DNA replication" EXACT [VZ:2656] +xref: VZ:2656 "Rolling hairpin replication" +is_a: GO:0039693 ! viral DNA genome replication +created_by: bf +creation_date: 2013-10-17T14:33:55Z + +[Term] +id: GO:0039686 +name: bidirectional double-stranded viral DNA replication +namespace: biological_process +def: "A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions." [GOC:bf, GOC:jl, VZ:1939] +synonym: "viral bidirectional dsDNA replication" EXACT [VZ:1939] +xref: VZ:1939 "dsDNA bidirectional replication" +is_a: GO:0039693 ! viral DNA genome replication +created_by: bf +creation_date: 2013-10-17T14:42:09Z + +[Term] +id: GO:0039687 +name: viral DNA strand displacement replication +namespace: biological_process +def: "A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA)." [GOC:bf, GOC:jl, VZ:1940] +xref: VZ:1940 "DNA strand displacement replication" +is_a: GO:0039693 ! viral DNA genome replication +created_by: bf +creation_date: 2013-10-17T14:48:40Z + +[Term] +id: GO:0039688 +name: viral double stranded DNA replication via reverse transcription +namespace: biological_process +def: "A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands." [GOC:bf, GOC:jl, VZ:1938] +synonym: "dsDNA replication via RNA intermediate" EXACT [GOC:bf, GOC:jl] +synonym: "RNA-dependent viral DNA replication" RELATED [GOC:bf, GOC:jl] +synonym: "viral RNA-dependent DNA replication" EXACT [GOC:bf, GOC:jl] +xref: VZ:1938 "dsDNA(RT) replication/transcription" +is_a: GO:0039693 ! viral DNA genome replication +relationship: has_part GO:0001171 ! reverse transcription +relationship: has_part GO:0039695 ! DNA-templated viral transcription +created_by: bf +creation_date: 2013-10-17T15:00:08Z + +[Term] +id: GO:0039689 +name: negative stranded viral RNA replication +namespace: biological_process +def: "A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA)." [GOC:bf, GOC:jl, VZ:1096] +synonym: "(-)ss viral RNA replication" EXACT [VZ:1096] +xref: VZ:1096 "Negative stranded RNA virus replication" +is_a: GO:0039694 ! viral RNA genome replication +relationship: has_part GO:0039696 ! RNA-templated viral transcription +created_by: bf +creation_date: 2013-10-17T15:40:27Z + +[Term] +id: GO:0039690 +name: positive stranded viral RNA replication +namespace: biological_process +def: "A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA." [GOC:bf, GOC:jl, VZ:1116] +synonym: "ss(+) viral RNA replication" RELATED [VZ:1116] +xref: VZ:1116 "Positive stranded RNA virus replication" +is_a: GO:0039694 ! viral RNA genome replication +created_by: bf +creation_date: 2013-10-17T15:45:40Z + +[Term] +id: GO:0039691 +name: double stranded viral RNA replication +namespace: biological_process +def: "A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA." [GOC:bf, GOC:jl, VZ:1936] +xref: VZ:1936 "Double-stranded RNA virus replication" +is_a: GO:0039694 ! viral RNA genome replication +relationship: has_part GO:0039696 ! RNA-templated viral transcription +created_by: bf +creation_date: 2013-10-17T15:52:19Z + +[Term] +id: GO:0039692 +name: single stranded viral RNA replication via double stranded DNA intermediate +namespace: biological_process +alt_id: GO:0045090 +def: "A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II." [GOC:bf, GOC:jl, ISBN:0198506732, VZ:1937] +synonym: "retroviral genome replication" EXACT [] +synonym: "viral ssRNA replication via dsDNA intermediate" RELATED [GOC:bf] +xref: VZ:1937 "ssRNA(RT) replication/transcription" +is_a: GO:0039694 ! viral RNA genome replication +relationship: has_part GO:0001171 ! reverse transcription +relationship: has_part GO:0039695 ! DNA-templated viral transcription +relationship: has_part GO:0044826 ! viral genome integration into host DNA +created_by: bf +creation_date: 2013-10-17T15:59:43Z + +[Term] +id: GO:0039693 +name: viral DNA genome replication +namespace: biological_process +alt_id: GO:0039681 +def: "The replication of a viral DNA genome." [GOC:bf, GOC:jl, VZ:915] +synonym: "DNA-dependent viral DNA replication" EXACT [GOC:bf, GOC:jl] +synonym: "viral DNA replication" EXACT [GOC:bf, GOC:jl] +synonym: "viral DNA-dependent DNA replication" EXACT [] +is_a: GO:0019079 ! viral genome replication +created_by: bf +creation_date: 2013-10-23T15:22:31Z + +[Term] +id: GO:0039694 +name: viral RNA genome replication +namespace: biological_process +def: "The replication of a viral RNA genome." [GOC:bf, GOC:jl] +is_a: GO:0019079 ! viral genome replication +created_by: bf +creation_date: 2013-10-23T15:24:36Z + +[Term] +id: GO:0039695 +name: DNA-templated viral transcription +namespace: biological_process +def: "A transcription process that uses a viral DNA as a template." [GOC:bf, GOC:jl] +xref: VZ:1942 "dsDNA templated transcription" +is_a: GO:0019083 ! viral transcription +created_by: bf +creation_date: 2013-10-28T13:25:20Z + +[Term] +id: GO:0039696 +name: RNA-templated viral transcription +namespace: biological_process +def: "A transcription process that uses viral RNA as a template." [GOC:bf, GOC:jl] +is_a: GO:0019083 ! viral transcription +created_by: bf +creation_date: 2013-10-28T13:28:01Z + +[Term] +id: GO:0039697 +name: negative stranded viral RNA transcription +namespace: biological_process +def: "A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template." [VZ:1096] +xref: VZ:1096 "Negative stranded RNA virus replication" +is_a: GO:0039696 ! RNA-templated viral transcription +created_by: bf +creation_date: 2013-10-28T14:41:41Z + +[Term] +id: GO:0039698 +name: polyadenylation of viral mRNA by polymerase stuttering +namespace: biological_process +def: "Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail." [VZ:1916] +synonym: "polyA stuttering" EXACT [VZ:1916] +xref: VZ:1916 "Negative-stranded RNA virus Polymerase stuttering" +is_a: GO:0043631 ! RNA polyadenylation +created_by: bf +creation_date: 2013-10-28T14:54:07Z + +[Term] +id: GO:0039699 +name: viral mRNA cap methylation +namespace: biological_process +def: "Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs." [UniProtKB-KW:KW-1196] +synonym: "IFIT mRNA restriction evasion by virus" EXACT [UniProtKB-KW:KW-1196] +is_a: GO:0039503 ! suppression by virus of host innate immune response +created_by: bf +creation_date: 2013-11-06T14:39:17Z + +[Term] +id: GO:0039700 +name: fusion of viral membrane with host outer nuclear membrane +namespace: biological_process +def: "Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit." [PMID:23057731, UniProtKB-KW:KW-1181] +synonym: "fusion of viral membrane with host outer nuclear membrane involved in nuclear egress" EXACT [GOC:bf] +synonym: "viral primary envelope fusion with host outer nuclear membrane" EXACT [UniProtKB-KW:KW-1181] +is_a: GO:0044800 ! multi-organism membrane fusion +relationship: part_of GO:0046802 ! exit of virus from host cell nucleus by nuclear egress +created_by: bf +creation_date: 2013-11-06T15:07:46Z + +[Term] +id: GO:0039701 +name: microtubule-dependent intracellular transport of viral material towards cell periphery +namespace: biological_process +def: "The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane." [UniProtKB-KW:KW-1189, VZ:1816] +xref: VZ:1816 "Microtubular outwards viral transport" +is_a: GO:0075519 ! microtubule-dependent intracellular transport of viral material +created_by: bf +creation_date: 2013-11-06T16:09:57Z + +[Term] +id: GO:0039702 +name: viral budding via host ESCRT complex +namespace: biological_process +def: "Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process." [UniProtKB-KW:KW-1187, VZ:1536] +synonym: "host-assisted viral budding" BROAD [VZ:1536] +synonym: "viral budding through the ESCRT machinery" RELATED [VZ:1536] +xref: VZ:1536 "Viral budding via the host ESCRT complexes" +is_a: GO:0046755 ! viral budding +created_by: bf +creation_date: 2013-11-06T16:51:53Z + +[Term] +id: GO:0039703 +name: RNA replication +namespace: biological_process +def: "The cellular metabolic process in which a cell duplicates one or more molecules of RNA." [GOC:bf, GOC:jl] +is_a: GO:0016070 ! RNA metabolic process +relationship: has_part GO:0032774 ! RNA biosynthetic process +created_by: bf +creation_date: 2013-11-21T16:53:29Z + +[Term] +id: GO:0039704 +name: viral translational shunt +namespace: biological_process +def: "A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site." [PMID:15827182, PMID:18195037, VZ:608] +comment: This term is intended to annotate gene products involved in the process of viral translational shunt, not viral proteins produced by this translation process. +synonym: "ribosomal shunt initiation pathway" EXACT [PMID:18195037] +xref: VZ:608 "Ribosomal shunt" +is_a: GO:0019081 ! viral translation +created_by: bf +creation_date: 2013-11-21T17:08:40Z + +[Term] +id: GO:0039705 +name: viral translational readthrough +namespace: biological_process +def: "The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons." [GOC:bf, GOC:ch, GOC:jl, PMID:10839817, VZ:859] +comment: This term is intended to annotate gene products involved in the process of viral translational readthrough, not viral proteins produced by this translation process. +synonym: "viral RNA suppression of termination" RELATED [VZ:859] +synonym: "viral stop codon readthrough" EXACT [VZ:859] +xref: VZ:859 "RNA suppression of termination" +is_a: GO:0006451 ! translational readthrough +relationship: part_of GO:0019081 ! viral translation +created_by: bf +creation_date: 2013-11-25T13:20:37Z + +[Term] +id: GO:0039706 +name: co-receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell." [GOC:bf, GOC:jl] +is_a: GO:0005515 ! protein binding +created_by: bf +creation_date: 2013-11-25T14:41:42Z + +[Term] +id: GO:0039707 +name: pore formation by virus in membrane of host cell +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism." [GOC:bf, GOC:jl, PMID:12972148, UniProtKB-KW:KW-1182] +synonym: "pore formation in membrane of host cell by virus" EXACT [GOC:bf] +synonym: "viroporin" RELATED [PMID:12972148, UniProtKB-KW:KW-1182] +is_a: GO:0016032 ! viral process +is_a: GO:0044658 ! pore formation in membrane of host by symbiont +created_by: bf +creation_date: 2013-11-25T15:33:33Z + +[Term] +id: GO:0039708 +name: nuclear capsid assembly +namespace: biological_process +def: "The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly." [VZ:1516] +xref: VZ:1516 "Nuclear capsid assembly" +is_a: GO:0019069 ! viral capsid assembly +intersection_of: GO:0019069 ! viral capsid assembly +intersection_of: occurs_in GO:0042025 ! host cell nucleus +relationship: occurs_in GO:0042025 ! host cell nucleus +created_by: bf +creation_date: 2013-11-28T15:08:41Z + +[Term] +id: GO:0039709 +name: cytoplasmic capsid assembly +namespace: biological_process +def: "The assembly of a virus capsid that occurs in the cytoplasm." [VZ:1950] +xref: VZ:1950 "Cytoplasmic capsid assembly/packaging" +is_a: GO:0019069 ! viral capsid assembly +intersection_of: GO:0019069 ! viral capsid assembly +intersection_of: occurs_in GO:0030430 ! host cell cytoplasm +relationship: occurs_in GO:0030430 ! host cell cytoplasm +created_by: bf +creation_date: 2013-11-28T15:12:30Z + +[Term] +id: GO:0039710 +name: cytoplasmic icosahedral capsid assembly +namespace: biological_process +def: "The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome." [VZ:1950] +is_a: GO:0039709 ! cytoplasmic capsid assembly +created_by: bf +creation_date: 2013-11-28T15:20:50Z + +[Term] +id: GO:0039711 +name: cytoplasmic helical capsid assembly +namespace: biological_process +def: "The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome." [VZ:1950] +is_a: GO:0039709 ! cytoplasmic capsid assembly +created_by: bf +creation_date: 2013-11-28T15:23:39Z + +[Term] +id: GO:0039712 +name: induction by virus of host catalytic activity +namespace: biological_process +def: "Any viral process that activates or increases the frequency, rate or extent of host catalytic activity." [GOC:bf, GOC:jl] +synonym: "induction by virus of host enzyme activity" EXACT [GOC:bf, GOC:jl] +is_a: GO:0039516 ! modulation by virus of host catalytic activity +is_a: GO:0043948 ! induction by symbiont of host catalytic activity +created_by: bf +creation_date: 2013-12-19T13:21:45Z + +[Term] +id: GO:0039713 +name: viral factory +namespace: cellular_component +def: "An intracellular compartment in a host cell which increases the efficiency of viral replication and/or assembly, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments." [PMID:22440839, VZ:1951] +synonym: "virus factory" EXACT [PMID:22440839] +xref: VZ:1951 "Viral factories" +is_a: GO:0033643 ! host cell part +created_by: bf +creation_date: 2013-12-19T14:53:47Z + +[Term] +id: GO:0039714 +name: cytoplasmic viral factory +namespace: cellular_component +def: "A viral factory located in the cytoplasm of a host cell." [VZ:1951] +is_a: GO:0033655 ! host cell cytoplasm part +is_a: GO:0039713 ! viral factory +intersection_of: GO:0039713 ! viral factory +intersection_of: part_of GO:0030430 ! host cell cytoplasm +created_by: bf +creation_date: 2013-12-19T15:16:15Z + +[Term] +id: GO:0039715 +name: nuclear viral factory +namespace: cellular_component +def: "A viral factory located in the nucleus of a host cell." [VZ:1951] +is_a: GO:0039713 ! viral factory +intersection_of: GO:0039713 ! viral factory +intersection_of: part_of GO:0042025 ! host cell nucleus +relationship: part_of GO:0042025 ! host cell nucleus +created_by: bf +creation_date: 2013-12-19T15:18:07Z + +[Term] +id: GO:0039716 +name: viroplasm viral factory +namespace: cellular_component +def: "A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae." [VZ:1951, Wikipedia:Viroplasm] +xref: Wikipedia:Viroplasm +is_a: GO:0039714 ! cytoplasmic viral factory +created_by: bf +creation_date: 2013-12-19T15:22:29Z + +[Term] +id: GO:0039717 +name: spherule viral factory +namespace: cellular_component +def: "A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus." [VZ:1951] +xref: Wikipedia:Viroplasm +is_a: GO:0039714 ! cytoplasmic viral factory +created_by: bf +creation_date: 2013-12-19T15:25:57Z + +[Term] +id: GO:0039718 +name: double membrane vesicle viral factory +namespace: cellular_component +def: "A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae." [PMID:22440839, VZ:1951] +synonym: "DMV viral factory" EXACT [VZ:1951] +is_a: GO:0039714 ! cytoplasmic viral factory +created_by: bf +creation_date: 2013-12-19T15:31:22Z + +[Term] +id: GO:0039719 +name: tube viral factory +namespace: cellular_component +def: "A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories." [VZ:1951] +is_a: GO:0039714 ! cytoplasmic viral factory +created_by: bf +creation_date: 2013-12-19T15:34:56Z + +[Term] +id: GO:0039720 +name: virogenic stroma +namespace: cellular_component +def: "A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled." [PMID:13358757, PMID:1433508, VZ:1951] +synonym: "VS" EXACT [VZ:1951] +is_a: GO:0039715 ! nuclear viral factory +created_by: bf +creation_date: 2013-12-19T15:45:32Z + +[Term] +id: GO:0039721 +name: peristromal region viral factory +namespace: cellular_component +def: "A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses." [PMID:18434402, VZ:1951] +synonym: "PR" RELATED [PMID:18434402, VZ:1951] +is_a: GO:0039715 ! nuclear viral factory +created_by: bf +creation_date: 2013-12-19T15:54:00Z + +[Term] +id: GO:0039722 +name: suppression by virus of host toll-like receptor signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism." [UniProtKB-KW:KW-1225] +synonym: "inhibition of host TLR pathway by virus" EXACT [UniProtKB-KW:KW-1125] +synonym: "suppression by virus of host TLR signaling pathway" EXACT [] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:0039503 ! suppression by virus of host innate immune response +created_by: bf +creation_date: 2014-01-06T11:39:58Z + +[Term] +id: GO:0039723 +name: suppression by virus of host TBK1 activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of the host serine/threonine kinase TBK1." [PR:000001779, UniProtKB-KW:KW-1223] +comment: When TBK1 acts as part of a TBK1-IKBKE-DDX3 complex, consider also annotating to: suppression by virus of host TBK1-IKBKE-DDX3 complex activity ; GO:0039659. +synonym: "inhibition of host TBK1 by virus" EXACT [UniProtKB-KW:KW-1223] +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039584 ! suppression by virus of host protein kinase activity +created_by: bf +creation_date: 2014-01-06T12:04:44Z + +[Term] +id: GO:0039724 +name: suppression by virus of host IKBKE activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the activity of the host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E)." [PR:000001778, UniProtKB-KW:KW-1224] +comment: When IKBKE acts as part of a TBK1-IKBKE-DDX3 complex, consider also annotating to: suppression by virus of host TBK1-IKBKE-DDX3 complex activity ; GO:0039659. +synonym: "inhibition of host IKBKE by virus" EXACT [UniProtKB-KW:KW-1224] +is_a: GO:0039503 ! suppression by virus of host innate immune response +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: bf +creation_date: 2014-01-06T12:15:03Z + +[Term] +id: GO:0040001 +name: establishment of mitotic spindle localization +namespace: biological_process +alt_id: GO:0018986 +alt_id: GO:0030605 +alt_id: GO:0030606 +alt_id: GO:0030608 +alt_id: GO:0030610 +def: "The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs." [GOC:ai] +synonym: "establishment of mitotic spindle localisation" EXACT [GOC:mah] +synonym: "mitotic spindle positioning" EXACT [] +synonym: "mitotic spindle positioning and orientation" NARROW [] +synonym: "mitotic spindle positioning or orientation" EXACT [] +synonym: "spindle positioning during mitosis" RELATED [] +synonym: "spindle positioning involved in mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051293 ! establishment of spindle localization +is_a: GO:1902850 ! microtubule cytoskeleton organization involved in mitosis +intersection_of: GO:0051293 ! establishment of spindle localization +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0040002 +name: collagen and cuticulin-based cuticle development +namespace: biological_process +def: "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans." [GOC:mtg_sensu] +synonym: "collagen and cuticulin-based cuticle anabolism" EXACT [] +synonym: "collagen and cuticulin-based cuticle biosynthetic process" EXACT [] +synonym: "collagen and cuticulin-based cuticle formation" EXACT [] +synonym: "collagen and cuticulin-based cuticle synthesis" EXACT [] +is_a: GO:0042335 ! cuticle development + +[Term] +id: GO:0040003 +name: chitin-based cuticle development +namespace: biological_process +def: "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu] +synonym: "chitin-based cuticle anabolism" EXACT [] +synonym: "chitin-based cuticle biosynthetic process" EXACT [] +synonym: "chitin-based cuticle formation" EXACT [] +synonym: "chitin-based cuticle synthesis" EXACT [] +is_a: GO:0042335 ! cuticle development + +[Term] +id: GO:0040004 +name: collagen and cuticulin-based cuticle attachment to epithelium +namespace: biological_process +def: "Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans." [GOC:ems, GOC:mtg_sensu] +synonym: "cuticular attachment to epithelium" BROAD [] +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0018996 ! molting cycle, collagen and cuticulin-based cuticle + +[Term] +id: GO:0040005 +name: chitin-based cuticle attachment to epithelium +namespace: biological_process +def: "Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] +synonym: "cuticular attachment to epithelium" BROAD [] +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle + +[Term] +id: GO:0040006 +name: obsolete protein-based cuticle attachment to epithelium +namespace: biological_process +def: "OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it." [GOC:jl, GOC:mtg_sensu] +comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term. +synonym: "cuticular attachment to epithelium" BROAD [] +synonym: "protein-based cuticle attachment to epithelium" EXACT [] +is_obsolete: true +consider: GO:0040004 +consider: GO:0040005 + +[Term] +id: GO:0040007 +name: growth +namespace: biological_process +alt_id: GO:0048590 +def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] +comment: See also the biological process term 'cell growth ; GO:0016049'. +subset: gocheck_do_not_annotate +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +subset: goslim_plant +synonym: "growth pattern" RELATED [] +synonym: "non-developmental growth" RELATED [GOC:mah] +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase + +[Term] +id: GO:0040008 +name: regulation of growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0040007 ! growth +relationship: regulates GO:0040007 ! growth + +[Term] +id: GO:0040009 +name: regulation of growth rate +namespace: biological_process +def: "Any process that modulates the rate of growth of all or part of an organism." [GOC:mah] +comment: Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation. +is_a: GO:0040008 ! regulation of growth + +[Term] +id: GO:0040010 +name: positive regulation of growth rate +namespace: biological_process +def: "Any process that increases the rate of growth of all or part of an organism." [GOC:mah] +comment: Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation. +synonym: "activation of growth rate" NARROW [] +synonym: "stimulation of growth rate" NARROW [] +synonym: "up regulation of growth rate" EXACT [] +synonym: "up-regulation of growth rate" EXACT [] +synonym: "upregulation of growth rate" EXACT [] +is_a: GO:0040009 ! regulation of growth rate +is_a: GO:0045927 ! positive regulation of growth + +[Term] +id: GO:0040011 +name: locomotion +namespace: biological_process +def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0044848 ! biological phase +property_value: RO:0002161 NCBITaxon:451864 + +[Term] +id: GO:0040012 +name: regulation of locomotion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0040011 ! locomotion +relationship: regulates GO:0040011 ! locomotion + +[Term] +id: GO:0040013 +name: negative regulation of locomotion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] +synonym: "down regulation of locomotion" EXACT [] +synonym: "down-regulation of locomotion" EXACT [] +synonym: "downregulation of locomotion" EXACT [] +synonym: "inhibition of locomotion" NARROW [] +is_a: GO:0040012 ! regulation of locomotion +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0040011 ! locomotion +relationship: negatively_regulates GO:0040011 ! locomotion + +[Term] +id: GO:0040014 +name: regulation of multicellular organism growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] +synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035264 ! multicellular organism growth +relationship: regulates GO:0035264 ! multicellular organism growth + +[Term] +id: GO:0040015 +name: negative regulation of multicellular organism growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb] +synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb] +is_a: GO:0040014 ! regulation of multicellular organism growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035264 ! multicellular organism growth +relationship: negatively_regulates GO:0035264 ! multicellular organism growth + +[Term] +id: GO:0040016 +name: embryonic cleavage +namespace: biological_process +def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] +is_a: GO:0051301 ! cell division +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0040017 +name: positive regulation of locomotion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] +synonym: "activation of locomotion" NARROW [] +synonym: "stimulation of locomotion" NARROW [] +synonym: "up regulation of locomotion" EXACT [] +synonym: "up-regulation of locomotion" EXACT [] +synonym: "upregulation of locomotion" EXACT [] +is_a: GO:0040012 ! regulation of locomotion +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0040011 ! locomotion +relationship: positively_regulates GO:0040011 ! locomotion + +[Term] +id: GO:0040018 +name: positive regulation of multicellular organism growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb] +is_a: GO:0040014 ! regulation of multicellular organism growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035264 ! multicellular organism growth +relationship: positively_regulates GO:0035264 ! multicellular organism growth + +[Term] +id: GO:0040019 +name: positive regulation of embryonic development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators] +synonym: "activation of embryonic development" NARROW [] +synonym: "stimulation of embryonic development" NARROW [] +synonym: "up regulation of embryonic development" EXACT [] +synonym: "up-regulation of embryonic development" EXACT [] +synonym: "upregulation of embryonic development" EXACT [] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009790 ! embryo development +relationship: positively_regulates GO:0009790 ! embryo development + +[Term] +id: GO:0040020 +name: regulation of meiotic nuclear division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] +synonym: "regulation of meiosis" BROAD [GOC:vw] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:0051783 ! regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0140013 ! meiotic nuclear division +relationship: regulates GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0040021 +name: hermaphrodite germ-line sex determination +namespace: biological_process +alt_id: GO:0042005 +def: "The determination of sex and sexual phenotype in the germ line of a hermaphrodite." [GOC:ems] +is_a: GO:0018992 ! germ-line sex determination + +[Term] +id: GO:0040022 +name: feminization of hermaphroditic germ-line +namespace: biological_process +def: "The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite." [GOC:ems] +is_a: GO:0040021 ! hermaphrodite germ-line sex determination + +[Term] +id: GO:0040024 +name: dauer larval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:ems, ISBN:087969307X] +is_a: GO:0002119 ! nematode larval development + +[Term] +id: GO:0040025 +name: vulval development +namespace: biological_process +def: "The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." [GOC:ems, GOC:kmv, ISBN:087969307X] +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0002119 ! nematode larval development + +[Term] +id: GO:0040026 +name: positive regulation of vulval development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." [GOC:ems, GOC:kmv] +synonym: "activation of vulval development" RELATED [] +synonym: "stimulation of vulval development" RELATED [] +synonym: "up regulation of vulval development" RELATED [] +synonym: "up-regulation of vulval development" RELATED [] +synonym: "upregulation of vulval development" RELATED [] +is_a: GO:0040028 ! regulation of vulval development +is_a: GO:0061063 ! positive regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0040025 ! vulval development +relationship: positively_regulates GO:0040025 ! vulval development + +[Term] +id: GO:0040027 +name: negative regulation of vulval development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." [GOC:ems, GOC:kmv] +synonym: "down regulation of vulval development" EXACT [] +synonym: "down-regulation of vulval development" EXACT [] +synonym: "downregulation of vulval development" EXACT [] +synonym: "inhibition of vulval development" NARROW [] +is_a: GO:0040028 ! regulation of vulval development +is_a: GO:0061064 ! negative regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0040025 ! vulval development +relationship: negatively_regulates GO:0040025 ! vulval development + +[Term] +id: GO:0040028 +name: regulation of vulval development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." [GOC:kmv, GOC:ma] +is_a: GO:0061062 ! regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0040025 ! vulval development +relationship: regulates GO:0040025 ! vulval development + +[Term] +id: GO:0040029 +name: regulation of gene expression, epigenetic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence." [PMID:10521337, PMID:11498582] +subset: goslim_plant +is_a: GO:0010468 ! regulation of gene expression + +[Term] +id: GO:0040030 +name: regulation of molecular function, epigenetic +namespace: biological_process +def: "Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:ems, GOC:tb, PMID:10611975, PMID:11050225, PMID:11447696, PMID:11685242, PMID:11782551] +synonym: "regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] +is_a: GO:0065009 ! regulation of molecular function + +[Term] +id: GO:0040031 +name: snRNA modification +namespace: biological_process +def: "The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA." [GOC:jl] +is_a: GO:0009451 ! RNA modification +is_a: GO:0016073 ! snRNA metabolic process + +[Term] +id: GO:0040032 +name: post-embryonic body morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the post-embryonic soma are generated and organized." [GOC:ems, ISBN:0140512888] +comment: Note that this term was 'body morphogenesis (sensu Nematoda)'. +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0010171 ! body morphogenesis + +[Term] +id: GO:0040033 +name: negative regulation of translation, ncRNA-mediated +namespace: biological_process +def: "Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein." [GOC:dph, GOC:ems, GOC:tb] +synonym: "down regulation of mRNA translation, ncRNA-mediated" EXACT [] +synonym: "down-regulation of mRNA translation, ncRNA-mediated" EXACT [] +synonym: "downregulation of mRNA translation, ncRNA-mediated" EXACT [] +synonym: "inhibition of mRNA translation, ncRNA-mediated" NARROW [] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0045974 ! regulation of translation, ncRNA-mediated + +[Term] +id: GO:0040034 +name: regulation of development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909] +synonym: "developmental timing" RELATED [] +synonym: "heterochronic regulation of development" EXACT [] +synonym: "temporal regulation of development" EXACT [] +is_a: GO:0050793 ! regulation of developmental process + +[Term] +id: GO:0040035 +name: hermaphrodite genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures." [GOC:ems, ISBN:0140512888] +is_a: GO:0008406 ! gonad development +is_a: GO:0048806 ! genitalia development + +[Term] +id: GO:0040036 +name: regulation of fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "regulation of FGF receptor signaling pathway" EXACT [] +synonym: "regulation of FGF receptor signalling pathway" EXACT [] +synonym: "regulation of FGFR signaling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway +relationship: regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway + +[Term] +id: GO:0040037 +name: negative regulation of fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "down regulation of fibroblast growth factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of fibroblast growth factor receptor signaling pathway" EXACT [] +synonym: "downregulation of fibroblast growth factor receptor signaling pathway" EXACT [] +synonym: "inhibition of fibroblast growth factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of FGF receptor signaling pathway" EXACT [] +synonym: "negative regulation of FGF receptor signalling pathway" EXACT [] +synonym: "negative regulation of FGFR signaling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway +relationship: negatively_regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway + +[Term] +id: GO:0040038 +name: polar body extrusion after meiotic divisions +namespace: biological_process +def: "The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." [GOC:ems, ISBN:0198506732] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0033206 ! meiotic cytokinesis +relationship: part_of GO:0007143 ! female meiotic nuclear division + +[Term] +id: GO:0040039 +name: inductive cell migration +namespace: biological_process +def: "Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans." [ISBN:087969307X, ISBN:0879694882] +is_a: GO:0016477 ! cell migration + +[Term] +id: GO:0040040 +name: thermosensory behavior +namespace: biological_process +def: "Behavior that is dependent upon the sensation of temperature." [GOC:ems] +synonym: "behavioral response to temperature stimulus" EXACT [] +synonym: "behavioural response to temperature stimulus" EXACT [] +synonym: "thermosensory behaviour" EXACT [] +is_a: GO:0007610 ! behavior +is_a: GO:0009266 ! response to temperature stimulus + +[Term] +id: GO:0042000 +name: translocation of peptides or proteins into host +namespace: biological_process +alt_id: GO:0051808 +def: "The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "translocation of peptides or proteins into other organism during symbiotic interaction" BROAD [GOC:tb] +synonym: "translocation of peptides or proteins into other organism involved in symbiotic interaction" BROAD [] +synonym: "transport of peptides or proteins into host" EXACT [] +synonym: "transport of peptides or proteins into other organism during symbiotic interaction" BROAD [] +is_a: GO:0015031 ! protein transport +is_a: GO:0044417 ! translocation of molecules into host + +[Term] +id: GO:0042001 +name: hermaphrodite somatic sex determination +namespace: biological_process +alt_id: GO:0042002 +def: "The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans." [GOC:ems] +is_a: GO:0018993 ! somatic sex determination + +[Term] +id: GO:0042003 +name: masculinization of hermaphrodite soma +namespace: biological_process +def: "Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans." [GOC:ems] +is_a: GO:0042001 ! hermaphrodite somatic sex determination + +[Term] +id: GO:0042004 +name: feminization of hermaphrodite soma +namespace: biological_process +def: "Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans." [GOC:ems] +is_a: GO:0042001 ! hermaphrodite somatic sex determination + +[Term] +id: GO:0042006 +name: masculinization of hermaphroditic germ-line +namespace: biological_process +def: "The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans." [GOC:ems] +is_a: GO:0040021 ! hermaphrodite germ-line sex determination + +[Term] +id: GO:0042007 +name: interleukin-18 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-18." [GOC:jl] +synonym: "IL-18 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042008 +name: interleukin-18 receptor activity +namespace: molecular_function +def: "Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-18 receptor activity" EXACT [GOC:mah] +synonym: "IL-18R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042007 ! interleukin-18 binding +relationship: part_of GO:0035655 ! interleukin-18-mediated signaling pathway + +[Term] +id: GO:0042009 +name: interleukin-15 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-15." [GOC:jl] +synonym: "IL-15 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042010 +name: interleukin-15 receptor activity +namespace: molecular_function +def: "Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-15 receptor activity" EXACT [GOC:mah] +synonym: "IL-15R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042009 ! interleukin-15 binding +relationship: part_of GO:0035723 ! interleukin-15-mediated signaling pathway + +[Term] +id: GO:0042011 +name: interleukin-16 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-16." [GOC:jl] +synonym: "IL-16 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042012 +name: interleukin-16 receptor activity +namespace: molecular_function +def: "Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-16 receptor activity" EXACT [GOC:mah] +synonym: "IL-16R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042011 ! interleukin-16 binding + +[Term] +id: GO:0042013 +name: interleukin-19 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-19." [GOC:jl] +synonym: "IL-19 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042014 +name: interleukin-19 receptor activity +namespace: molecular_function +def: "Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-19 receptor activity" EXACT [GOC:mah] +synonym: "IL-19R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042013 ! interleukin-19 binding + +[Term] +id: GO:0042015 +name: interleukin-20 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-20." [GOC:jl] +synonym: "IL-20 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042016 +name: interleukin-20 receptor activity +namespace: molecular_function +def: "Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-20 receptor activity" EXACT [GOC:mah] +synonym: "IL-20R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042015 ! interleukin-20 binding + +[Term] +id: GO:0042017 +name: interleukin-22 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-22." [GOC:jl] +synonym: "IL-22 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042018 +name: interleukin-22 receptor activity +namespace: molecular_function +def: "Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-22 receptor activity" EXACT [GOC:mah] +synonym: "IL-22R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042017 ! interleukin-22 binding + +[Term] +id: GO:0042019 +name: interleukin-23 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-23." [GOC:jl] +synonym: "IL-23 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042020 +name: interleukin-23 receptor activity +namespace: molecular_function +def: "Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-23 receptor activity" EXACT [GOC:mah] +synonym: "IL-23R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0042019 ! interleukin-23 binding +relationship: part_of GO:0038155 ! interleukin-23-mediated signaling pathway + +[Term] +id: GO:0042021 +name: granulocyte macrophage colony-stimulating factor complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor complex." [GOC:ai] +synonym: "GM-CSF complex binding" EXACT [] +synonym: "GMC-SF complex binding" EXACT [] +synonym: "granulocyte macrophage colony stimulating factor complex binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0042022 +name: interleukin-12 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits." [GOC:ebc, GOC:mah, PMID:10971505] +synonym: "IL-12 receptor complex" EXACT [GOC:add] +synonym: "IL12RB1-IL12RB2 complex" NARROW [CORUM:2026] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0042023 +name: DNA endoreduplication +namespace: biological_process +def: "Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes." [GOC:jl, GOC:vw] +comment: Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states. +synonym: "DNA endoreplication" EXACT [] +synonym: "DNA re-duplication" EXACT [] +is_a: GO:0044786 ! cell cycle DNA replication +relationship: has_part GO:0006270 ! DNA replication initiation +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0042025 +name: host cell nucleus +namespace: cellular_component +alt_id: GO:0033649 +def: "A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle + +[Term] +id: GO:0042026 +name: protein refolding +namespace: biological_process +def: "The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones." [GOC:mb] +synonym: "heat shock protein activity" RELATED [] +is_a: GO:0006457 ! protein folding + +[Term] +id: GO:0042027 +name: obsolete cyclophilin-type peptidyl-prolyl cis-trans isomerase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: peptidylproline (omega=180) = peptidylproline (omega=0)." [EC:5.2.1.8] +comment: This term was made obsolete because it is contains gene product specific characteristics. +synonym: "cyclophilin-type peptidyl-prolyl cis-trans isomerase activity" EXACT [] +is_obsolete: true +consider: GO:0003755 + +[Term] +id: GO:0042029 +name: obsolete fibrolase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen." [EC:3.4.24.72, PMID:7725320] +comment: This term was made obsolete because it represents a gene product. +synonym: "Agkistrodon contortrix contortrix metalloproteinase activity" NARROW [EC:3.4.24.72] +synonym: "Agkistrodon contortrix contortrix venom metalloproteinase activity" NARROW [EC:3.4.24.72] +synonym: "fibrinolytic proteinase activity" EXACT [EC:3.4.24.72] +synonym: "fibrolase activity" EXACT [] +xref: EC:3.4.24.72 +xref: MetaCyc:3.4.24.72-RXN +is_obsolete: true +replaced_by: GO:0004222 + +[Term] +id: GO:0042030 +name: ATPase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate." [GOC:jl] +synonym: "adenosinetriphosphatase inhibitor" EXACT [] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0060590 ! ATPase regulator activity +relationship: negatively_regulates GO:0016887 ! ATPase activity + +[Term] +id: GO:0042031 +name: obsolete angiotensin-converting enzyme inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I." [GOC:jl] +comment: This term was made obsolete because it represents a regulator of a non-existent molecular function term. +synonym: "ACE inhibitor" EXACT [] +synonym: "angiotensin-converting enzyme inhibitor activity" EXACT [] +synonym: "peptidyl dipeptidase A inhibitor" EXACT [] +xref: Wikipedia:ACE_inhibitor +is_obsolete: true +replaced_by: GO:0060422 + +[Term] +id: GO:0042033 +name: chemokine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, ISBN:0198506732, PMID:12183377, Wikipedia:Chemokine] +synonym: "chemokine anabolism" EXACT [] +synonym: "chemokine biosynthesis" EXACT [] +synonym: "chemokine formation" EXACT [] +synonym: "chemokine synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:0050755 ! chemokine metabolic process +relationship: part_of GO:0032602 ! chemokine production + +[Term] +id: GO:0042034 +name: peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine +namespace: biological_process +def: "The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester." [RESID:AA0318] +synonym: "peptidyl-lysine esterification" EXACT [] +xref: RESID:AA0318 +is_a: GO:0006481 ! C-terminal protein methylation +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0042035 +name: regulation of cytokine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] +synonym: "regulation of cytokine anabolism" EXACT [] +synonym: "regulation of cytokine biosynthesis" EXACT [] +synonym: "regulation of cytokine formation" EXACT [] +synonym: "regulation of cytokine synthesis" EXACT [] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042089 ! cytokine biosynthetic process +relationship: regulates GO:0042089 ! cytokine biosynthetic process + +[Term] +id: GO:0042036 +name: negative regulation of cytokine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] +synonym: "down regulation of cytokine biosynthetic process" EXACT [] +synonym: "down-regulation of cytokine biosynthetic process" EXACT [] +synonym: "downregulation of cytokine biosynthetic process" EXACT [] +synonym: "inhibition of cytokine biosynthetic process" NARROW [] +synonym: "negative regulation of cytokine anabolism" EXACT [] +synonym: "negative regulation of cytokine biosynthesis" EXACT [] +synonym: "negative regulation of cytokine formation" EXACT [] +synonym: "negative regulation of cytokine synthesis" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042089 ! cytokine biosynthetic process +relationship: negatively_regulates GO:0042089 ! cytokine biosynthetic process + +[Term] +id: GO:0042037 +name: peptidyl-histidine methylation, to form pros-methylhistidine +namespace: biological_process +alt_id: GO:0042260 +def: "The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)." [RESID:AA0073] +synonym: "peptidyl-histidine pros-methylation" EXACT [] +xref: RESID:AA0073 +is_a: GO:0018021 ! peptidyl-histidine methylation + +[Term] +id: GO:0042038 +name: peptidyl-histidine methylation, to form tele-methylhistidine +namespace: biological_process +alt_id: GO:0042261 +def: "The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine)." [RESID:AA0317] +synonym: "peptidyl-histidine tele-methylation" EXACT [] +xref: RESID:AA0317 +is_a: GO:0018021 ! peptidyl-histidine methylation + +[Term] +id: GO:0042039 +name: vanadium incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n)." [PMID:11053414] +synonym: "vanadium incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0042040 +name: metal incorporation into metallo-molybdopterin complex +namespace: biological_process +def: "The incorporation of a metal into a metallo-molybdopterin complex." [GOC:ai] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0042042 +name: tungsten incorporation into tungsten-molybdopterin complex +namespace: biological_process +def: "The incorporation of tungsten into a tungsten-molybdopterin complex." [GOC:ai] +is_a: GO:0042040 ! metal incorporation into metallo-molybdopterin complex + +[Term] +id: GO:0042043 +name: neurexin family protein binding +namespace: molecular_function +alt_id: GO:0019963 +def: "Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals." [GOC:curators, GOC:pr, PMID:18923512] +synonym: "neuroligin" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042044 +name: fluid transport +namespace: biological_process +def: "The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_pir +is_a: GO:0006810 ! transport + +[Term] +id: GO:0042045 +name: epithelial fluid transport +namespace: biological_process +def: "The directed movement of fluid across epithelia." [GOC:jl, PMID:11390830] +is_a: GO:0042044 ! fluid transport +is_a: GO:0070633 ! transepithelial transport + +[Term] +id: GO:0042046 +name: W-molybdopterin cofactor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands." [ISSN:09498257] +synonym: "Moco metabolic process" BROAD [] +synonym: "Moco metabolism" BROAD [] +synonym: "W-molybdopterin cofactor metabolism" EXACT [] +is_a: GO:0043545 ! molybdopterin cofactor metabolic process + +[Term] +id: GO:0042047 +name: W-molybdopterin cofactor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands." [ISSN:09498257] +synonym: "Moco biosynthesis" BROAD [] +synonym: "Moco biosynthetic process" BROAD [] +synonym: "W-molybdopterin cofactor anabolism" EXACT [] +synonym: "W-molybdopterin cofactor biosynthesis" EXACT [] +synonym: "W-molybdopterin cofactor formation" EXACT [] +synonym: "W-molybdopterin cofactor synthesis" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042046 ! W-molybdopterin cofactor metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: has_part GO:0042042 ! tungsten incorporation into tungsten-molybdopterin complex + +[Term] +id: GO:0042048 +name: olfactory behavior +namespace: biological_process +def: "The behavior of an organism in response to an odor." [GOC:jid, GOC:pr] +synonym: "behavioral response to scent" EXACT [] +synonym: "behavioral response to smell" EXACT [] +synonym: "behavioural response to odour" EXACT [] +synonym: "behavioural response to scent" EXACT [] +synonym: "behavioural response to smell" EXACT [] +synonym: "olfactory behaviour" EXACT [] +is_a: GO:0007635 ! chemosensory behavior + +[Term] +id: GO:0042049 +name: cellular acyl-CoA homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment." [GOC:ai, GOC:dph, GOC:tb] +synonym: "cell acyl-CoA homeostasis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030002 ! cellular anion homeostasis + +[Term] +id: GO:0042051 +name: compound eye photoreceptor development +namespace: biological_process +def: "The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure." [GOC:bf] +synonym: "adult eye photoreceptor development" NARROW [] +is_a: GO:0042462 ! eye photoreceptor cell development +relationship: part_of GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0042052 +name: rhabdomere development +namespace: biological_process +def: "The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments." [PMID:3076112, PMID:3937883] +synonym: "rhabdomere organization" EXACT [GOC:mah] +is_a: GO:0006996 ! organelle organization +relationship: part_of GO:0042051 ! compound eye photoreceptor development + +[Term] +id: GO:0042053 +name: regulation of dopamine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] +synonym: "regulation of dopamine metabolism" EXACT [] +is_a: GO:0042069 ! regulation of catecholamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042417 ! dopamine metabolic process +relationship: regulates GO:0042417 ! dopamine metabolic process + +[Term] +id: GO:0042054 +name: histone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue." [EC:2.1.1.43] +synonym: "histone methylase activity" EXACT [GOC:mah] +is_a: GO:0008276 ! protein methyltransferase activity +relationship: part_of GO:0016571 ! histone methylation + +[Term] +id: GO:0042056 +name: chemoattractant activity +namespace: molecular_function +def: "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal." [GOC:go_curators, ISBN:0198506732] +subset: goslim_chembl +subset: goslim_pir +synonym: "attractant" BROAD [] +is_a: GO:0048018 ! receptor ligand activity +relationship: part_of GO:0050918 ! positive chemotaxis + +[Term] +id: GO:0042057 +name: obsolete transforming growth factor beta receptor anchoring activity +namespace: molecular_function +def: "OBSOLETE. Binds to transforming growth factor beta receptor and anchors it to a particular subcellular location." [GOC:ai] +comment: This term was made obsolete because it represents a combination of process and function information. +synonym: "TGF-beta receptor anchoring activity" EXACT [] +synonym: "TGFbeta receptor anchoring activity" EXACT [] +synonym: "transforming growth factor beta receptor anchor activity" EXACT [] +synonym: "transforming growth factor beta receptor anchoring activity" EXACT [] +is_obsolete: true +consider: GO:0005160 +consider: GO:0008104 + +[Term] +id: GO:0042058 +name: regulation of epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "regulation of EGF receptor signaling pathway" EXACT [] +synonym: "regulation of EGF receptor signalling pathway" EXACT [] +synonym: "regulation of EGFR signaling pathway" EXACT [] +is_a: GO:1901184 ! regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: regulates GO:0007173 ! epidermal growth factor receptor signaling pathway + +[Term] +id: GO:0042059 +name: negative regulation of epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "down regulation of epidermal growth factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of epidermal growth factor receptor signaling pathway" EXACT [] +synonym: "downregulation of epidermal growth factor receptor signaling pathway" EXACT [] +synonym: "inhibition of epidermal growth factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of EGF receptor signaling pathway" EXACT [] +synonym: "negative regulation of EGF receptor signalling pathway" EXACT [] +synonym: "negative regulation of EGFR signaling pathway" EXACT [] +is_a: GO:0042058 ! regulation of epidermal growth factor receptor signaling pathway +is_a: GO:1901185 ! negative regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: negatively_regulates GO:0007173 ! epidermal growth factor receptor signaling pathway + +[Term] +id: GO:0042060 +name: wound healing +namespace: biological_process +def: "The series of events that restore integrity to a damaged tissue, following an injury." [GOC:bf, PMID:15269788] +xref: Wikipedia:Wound_healing +is_a: GO:0009611 ! response to wounding + +[Term] +id: GO:0042062 +name: long-term strengthening of neuromuscular junction +namespace: biological_process +def: "Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse." [GO_REF:0000021] +is_a: GO:0050806 ! positive regulation of synaptic transmission +relationship: part_of GO:0008582 ! regulation of synaptic growth at neuromuscular junction + +[Term] +id: GO:0042063 +name: gliogenesis +namespace: biological_process +def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid] +synonym: "glial cell generation" EXACT systematic_synonym [] +is_a: GO:0022008 ! neurogenesis + +[Term] +id: GO:0042064 +name: obsolete cell adhesion receptor regulator activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cell adhesion receptor regulator activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0030155 + +[Term] +id: GO:0042065 +name: glial cell growth +namespace: biological_process +def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid] +is_a: GO:0048588 ! developmental cell growth +relationship: part_of GO:0042063 ! gliogenesis + +[Term] +id: GO:0042066 +name: perineurial glial growth +namespace: biological_process +def: "Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons." [GOC:mah, PMID:11517334, PMID:18176560] +is_a: GO:0042065 ! glial cell growth + +[Term] +id: GO:0042067 +name: establishment of ommatidial planar polarity +namespace: biological_process +def: "The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:3076112, PMID:3937883] +synonym: "establishment of ommatidial polarity" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0001736 ! establishment of planar polarity +is_a: GO:0007163 ! establishment or maintenance of cell polarity +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0042068 +name: regulation of pteridine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] +synonym: "regulation of pteridine metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019889 ! pteridine metabolic process +relationship: regulates GO:0019889 ! pteridine metabolic process + +[Term] +id: GO:0042069 +name: regulation of catecholamine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] +synonym: "regulation of catecholamine metabolism" EXACT [] +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006584 ! catecholamine metabolic process +relationship: regulates GO:0006584 ! catecholamine metabolic process + +[Term] +id: GO:0042070 +name: maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification +namespace: biological_process +alt_id: GO:0048127 +def: "Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster." [GOC:dph, GOC:mah, GOC:mtg_sensu, GOC:tb] +synonym: "maintenance of oocyte nucleus localization during oocyte axis determination" BROAD [GOC:dph, GOC:tb] +synonym: "maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification" EXACT [GOC:mah] +synonym: "maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination" EXACT [GOC:dph, GOC:tb] +synonym: "maintenance of oocyte nucleus location involved in oocyte dorsoventral axis specification" EXACT [GOC:mah] +synonym: "maintenance of oocyte nucleus position during oocyte axis determination" BROAD [] +synonym: "oocyte axis determination, maintenance of oocyte nucleus localization" BROAD [] +synonym: "oocyte axis determination, maintenance of oocyte nucleus position" BROAD [] +synonym: "oocyte axis determination, oocyte nucleus anchoring" BROAD [] +synonym: "oocyte nucleus anchoring during oocyte axis determination" BROAD [] +is_a: GO:0051658 ! maintenance of nucleus location +is_a: GO:0051663 ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification +intersection_of: GO:0051658 ! maintenance of nucleus location +intersection_of: part_of GO:0007310 ! oocyte dorsal/ventral axis specification + +[Term] +id: GO:0042071 +name: leucokinin receptor activity +namespace: molecular_function +def: "Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity." [GOC:mah, GOC:signaling, PMID:2716741] +is_a: GO:0038023 ! signaling receptor activity +relationship: part_of GO:0009755 ! hormone-mediated signaling pathway + +[Term] +id: GO:0042072 +name: obsolete cell adhesion receptor inhibitor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "cell adhesion receptor inhibitor activity" EXACT [] +is_obsolete: true +consider: GO:0005102 +consider: GO:0007162 + +[Term] +id: GO:0042073 +name: intraciliary transport +namespace: biological_process +alt_id: GO:0035734 +def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "IFT" RELATED [] +synonym: "intraflagellar transport" EXACT [] +synonym: "intraflagellar transport involved in cilium organization" EXACT [] +synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT [] +xref: Wikipedia:Intraflagellar_transport +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0098840 ! protein transport along microtubule +relationship: occurs_in GO:0005929 ! cilium +relationship: part_of GO:0044782 ! cilium organization +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +property_value: RO:0002161 NCBITaxon:4890 +property_value: RO:0002161 NCBITaxon:5782 + +[Term] +id: GO:0042074 +name: cell migration involved in gastrulation +namespace: biological_process +def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437] +is_a: GO:0001667 ! ameboidal-type cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0007369 ! gastrulation + +[Term] +id: GO:0042075 +name: nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide +namespace: biological_process +def: "The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase." [RESID:AA0310] +synonym: "nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide" EXACT [] +xref: RESID:AA0310 +is_a: GO:0016226 ! iron-sulfur cluster assembly +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018202 ! peptidyl-histidine modification +is_a: GO:0018414 ! nickel incorporation into metallo-sulfur cluster + +[Term] +id: GO:0042076 +name: protein phosphate-linked glycosylation +namespace: biological_process +def: "The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues." [PMID:7499424] +synonym: "phosphoglycosylation" EXACT [] +synonym: "protein amino acid phosphate-linked glycosylation" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0042077 +name: protein phosphate-linked glycosylation via serine +namespace: biological_process +def: "The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues." [GOC:mah] +synonym: "protein amino acid phosphate-linked glycosylation via serine" EXACT [GOC:bf] +is_a: GO:0042076 ! protein phosphate-linked glycosylation + +[Term] +id: GO:0042078 +name: germ-line stem cell division +namespace: biological_process +alt_id: GO:0048131 +def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] +synonym: "germ-line stem cell renewal" EXACT [] +is_a: GO:0017145 ! stem cell division +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007281 ! germ cell development + +[Term] +id: GO:0042079 +name: obsolete GPI/GSI anchor metabolic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it is a composite term that represents two individual processes. +synonym: "GPI/GSI anchor metabolic process" EXACT [] +is_obsolete: true +consider: GO:0006505 +consider: GO:0042081 + +[Term] +id: GO:0042080 +name: obsolete GPI/GSI anchor biosynthetic process +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:ai] +comment: This term was made obsolete because it is a composite term that represents two individual processes. +synonym: "GPI/GSI anchor anabolism" EXACT [] +synonym: "GPI/GSI anchor biosynthesis" EXACT [] +synonym: "GPI/GSI anchor biosynthetic process" EXACT [] +synonym: "GPI/GSI anchor formation" EXACT [] +synonym: "GPI/GSI anchor synthesis" EXACT [] +is_obsolete: true +consider: GO:0006506 +consider: GO:0042082 + +[Term] +id: GO:0042081 +name: GSI anchor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane." [GOC:go_curators] +synonym: "GPI/GSI anchor metabolic process" BROAD [] +synonym: "GPI/GSI anchor metabolism" BROAD [] +synonym: "GSI anchor metabolism" EXACT [] +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0042082 +name: GSI anchor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage." [GOC:go_curators, GOC:jsg] +synonym: "GPI/GSI anchor biosynthesis" BROAD [] +synonym: "GPI/GSI anchor biosynthetic process" BROAD [] +synonym: "GSI anchor anabolism" EXACT [] +synonym: "GSI anchor biosynthesis" EXACT [] +synonym: "GSI anchor formation" EXACT [] +synonym: "GSI anchor synthesis" EXACT [] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +is_a: GO:0042081 ! GSI anchor metabolic process + +[Term] +id: GO:0042083 +name: 5,10-methylenetetrahydrofolate-dependent methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate." [GOC:ai] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0042084 +name: 5-methyltetrahydrofolate-dependent methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate." [GOC:ai] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0042085 +name: 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate." [GOC:ai] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0042086 +name: 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin." [GOC:ai] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0042088 +name: T-helper 1 type immune response +namespace: biological_process +def: "An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin." [GOC:add, ISBN:0781735149] +synonym: "Th1 immune response" EXACT [] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + +[Term] +id: GO:0042089 +name: cytokine biosynthetic process +namespace: biological_process +alt_id: GO:0042032 +def: "The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." [GOC:bf, ISBN:0198506732, ISBN:0198599471] +synonym: "cytokine anabolism" EXACT [] +synonym: "cytokine biosynthesis" EXACT [] +synonym: "cytokine formation" EXACT [] +synonym: "cytokine synthesis" EXACT [] +synonym: "induction of cytokines" NARROW [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0042107 ! cytokine metabolic process +relationship: part_of GO:0001816 ! cytokine production + +[Term] +id: GO:0042090 +name: interleukin-12 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] +synonym: "IL-12 biosynthesis" EXACT [] +synonym: "IL-12 biosynthetic process" EXACT [] +synonym: "interleukin-12 anabolism" EXACT [] +synonym: "interleukin-12 biosynthesis" EXACT [] +synonym: "interleukin-12 formation" EXACT [] +synonym: "interleukin-12 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032615 ! interleukin-12 production + +[Term] +id: GO:0042091 +name: interleukin-10 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] +synonym: "IL-10 biosynthesis" EXACT [] +synonym: "IL-10 biosynthetic process" EXACT [] +synonym: "interleukin-10 anabolism" EXACT [] +synonym: "interleukin-10 biosynthesis" EXACT [] +synonym: "interleukin-10 formation" EXACT [] +synonym: "interleukin-10 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032613 ! interleukin-10 production + +[Term] +id: GO:0042092 +name: type 2 immune response +namespace: biological_process +def: "An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects." [GOC:add, ISBN:0781735149, PMID:18000958, PMID:18007680, PMID:20065995, PMID:20200518] +synonym: "T-helper 2 type immune response" NARROW [GOC:add] +synonym: "Th2 immune response" NARROW [GOC:add] +is_a: GO:0006955 ! immune response + +[Term] +id: GO:0042093 +name: T-helper cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell." [GOC:ebc] +synonym: "helper T cell differentiation" EXACT [CL:0000912] +synonym: "T-helper cell development" RELATED [GOC:add] +is_a: GO:0002294 ! CD4-positive, alpha-beta T cell differentiation involved in immune response + +[Term] +id: GO:0042094 +name: interleukin-2 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] +synonym: "IL-2 biosynthesis" EXACT [] +synonym: "IL-2 biosynthetic process" EXACT [] +synonym: "interleukin-2 anabolism" EXACT [] +synonym: "interleukin-2 biosynthesis" EXACT [] +synonym: "interleukin-2 formation" EXACT [] +synonym: "interleukin-2 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032623 ! interleukin-2 production + +[Term] +id: GO:0042095 +name: interferon-gamma biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon found so far." [GOC:go_curators, PR:000000017] +synonym: "IFN-gamma biosynthesis" EXACT [] +synonym: "IFN-gamma biosynthetic process" EXACT [] +synonym: "interferon type II biosynthesis" BROAD [] +synonym: "interferon type II biosynthetic process" BROAD [] +synonym: "interferon-gamma anabolism" EXACT [] +synonym: "interferon-gamma biosynthesis" EXACT [] +synonym: "interferon-gamma formation" EXACT [] +synonym: "interferon-gamma synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032609 ! interferon-gamma production + +[Term] +id: GO:0042096 +name: obsolete alpha-beta T cell receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes a receptor type, and not an activity. +synonym: "alpha-beta T cell receptor activity" EXACT [] +is_obsolete: true +consider: GO:0032394 +consider: GO:0032395 +consider: GO:0042605 + +[Term] +id: GO:0042097 +name: interleukin-4 biosynthetic process +namespace: biological_process +alt_id: GO:0042224 +def: "The chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] +synonym: "IL-4 biosynthesis" EXACT [] +synonym: "IL-4 biosynthetic process" EXACT [] +synonym: "interleukin-4 anabolism" EXACT [] +synonym: "interleukin-4 biosynthesis" EXACT [] +synonym: "interleukin-4 formation" EXACT [] +synonym: "interleukin-4 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032633 ! interleukin-4 production + +[Term] +id: GO:0042098 +name: T cell proliferation +namespace: biological_process +alt_id: GO:0042111 +def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] +synonym: "T lymphocyte proliferation" EXACT [] +synonym: "T-cell proliferation" EXACT [] +synonym: "T-lymphocyte proliferation" EXACT [] +is_a: GO:0042110 ! T cell activation +is_a: GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0042099 +name: obsolete gamma-delta T cell receptor activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:jl] +comment: This term was made obsolete because it describes a receptor type, and not an activity. +synonym: "gamma-delta T cell receptor activity" EXACT [] +is_obsolete: true +consider: GO:0032394 +consider: GO:0032395 +consider: GO:0042605 + +[Term] +id: GO:0042100 +name: B cell proliferation +namespace: biological_process +alt_id: GO:0042114 +def: "The expansion of a B cell population by cell division. Follows B cell activation." [GOC:jl] +synonym: "B lymphocyte proliferation" EXACT [] +synonym: "B-cell proliferation" EXACT [] +synonym: "B-lymphocyte proliferation" EXACT [] +is_a: GO:0042113 ! B cell activation +is_a: GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0042101 +name: T cell receptor complex +namespace: cellular_component +def: "A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains." [GOC:mah, ISBN:0781735149] +synonym: "T lymphocyte receptor complex" EXACT [] +synonym: "T-cell receptor complex" EXACT [] +synonym: "T-lymphocyte receptor complex" EXACT [] +synonym: "TCR" RELATED [] +synonym: "TCR complex" EXACT [GOC:bf] +xref: Wikipedia:T_cell_receptor +is_a: GO:0098802 ! plasma membrane signaling receptor complex + +[Term] +id: GO:0042102 +name: positive regulation of T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] +synonym: "activation of T cell proliferation" NARROW [] +synonym: "positive regulation of T lymphocyte proliferation" EXACT [] +synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] +synonym: "stimulation of T cell proliferation" NARROW [] +synonym: "up regulation of T cell proliferation" EXACT [] +synonym: "up-regulation of T cell proliferation" EXACT [] +synonym: "upregulation of T cell proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +is_a: GO:0050671 ! positive regulation of lymphocyte proliferation +is_a: GO:0050870 ! positive regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042098 ! T cell proliferation +relationship: positively_regulates GO:0042098 ! T cell proliferation + +[Term] +id: GO:0042103 +name: positive regulation of T cell homeostatic proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] +synonym: "activation of T cell homeostatic proliferation" NARROW [] +synonym: "positive regulation of resting T cell proliferation" EXACT [] +synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] +synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] +synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] +synonym: "stimulation of T cell homeostatic proliferation" NARROW [] +synonym: "up regulation of T cell homeostatic proliferation" EXACT [] +synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] +synonym: "upregulation of T cell homeostatic proliferation" EXACT [] +is_a: GO:0042102 ! positive regulation of T cell proliferation +is_a: GO:0046013 ! regulation of T cell homeostatic proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001777 ! T cell homeostatic proliferation +relationship: positively_regulates GO:0001777 ! T cell homeostatic proliferation + +[Term] +id: GO:0042104 +name: positive regulation of activated T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of activated T cell proliferation." [GOC:jl] +synonym: "activation of activated T cell proliferation" NARROW [] +synonym: "positive regulation of activated T lymphocyte proliferation" EXACT [] +synonym: "positive regulation of activated T-cell proliferation" EXACT [] +synonym: "positive regulation of activated T-lymphocyte proliferation" EXACT [] +synonym: "stimulation of activated T cell proliferation" NARROW [] +synonym: "up regulation of activated T cell proliferation" EXACT [] +synonym: "up-regulation of activated T cell proliferation" EXACT [] +synonym: "upregulation of activated T cell proliferation" EXACT [] +is_a: GO:0042102 ! positive regulation of T cell proliferation +is_a: GO:0046006 ! regulation of activated T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050798 ! activated T cell proliferation +relationship: positively_regulates GO:0050798 ! activated T cell proliferation + +[Term] +id: GO:0042105 +name: alpha-beta T cell receptor complex +namespace: cellular_component +def: "A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein." [GOC:mah, ISBN:0781735149] +synonym: "alpha-beta T lymphocyte receptor complex" EXACT [] +synonym: "alpha-beta T-cell receptor complex" EXACT [] +synonym: "alpha-beta T-lymphocyte receptor complex" EXACT [] +synonym: "alpha-beta TCR complex" EXACT [] +is_a: GO:0042101 ! T cell receptor complex + +[Term] +id: GO:0042106 +name: gamma-delta T cell receptor complex +namespace: cellular_component +def: "A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein." [GOC:mah, ISBN:0781735149] +synonym: "gamma-delta T lymphocyte receptor complex" EXACT [] +synonym: "gamma-delta T-cell receptor complex" EXACT [] +synonym: "gamma-delta T-lymphocyte receptor complex" EXACT [] +synonym: "gamma-delta TCR complex" EXACT [] +is_a: GO:0042101 ! T cell receptor complex + +[Term] +id: GO:0042107 +name: cytokine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." [GO_REF:0000022, GOC:bf, GOC:BHF, ISBN:0198599471] +synonym: "cytokine metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process + +[Term] +id: GO:0042108 +name: positive regulation of cytokine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] +synonym: "activation of cytokine biosynthetic process" NARROW [] +synonym: "positive regulation of cytokine anabolism" EXACT [] +synonym: "positive regulation of cytokine biosynthesis" EXACT [] +synonym: "positive regulation of cytokine formation" EXACT [] +synonym: "positive regulation of cytokine synthesis" EXACT [] +synonym: "stimulation of cytokine biosynthetic process" NARROW [] +synonym: "up regulation of cytokine biosynthetic process" EXACT [] +synonym: "up-regulation of cytokine biosynthetic process" EXACT [] +synonym: "upregulation of cytokine biosynthetic process" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042089 ! cytokine biosynthetic process +relationship: positively_regulates GO:0042089 ! cytokine biosynthetic process + +[Term] +id: GO:0042109 +name: lymphotoxin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] +synonym: "LTA biosynthesis" BROAD [] +synonym: "LTA biosynthetic process" BROAD [] +synonym: "lymphotoxin A anabolism" EXACT [] +synonym: "lymphotoxin A biosynthesis" EXACT [] +synonym: "lymphotoxin A formation" EXACT [] +synonym: "lymphotoxin A synthesis" EXACT [] +synonym: "lymphotoxin-alpha biosynthesis" EXACT [] +synonym: "lymphotoxin-alpha biosynthetic process" EXACT [] +synonym: "TNF-B biosynthesis" EXACT [] +synonym: "TNF-B biosynthetic process" EXACT [] +synonym: "TNF-beta biosynthesis" EXACT [] +synonym: "TNF-beta biosynthetic process" EXACT [] +synonym: "tumor necrosis factor-beta biosynthesis" EXACT [] +synonym: "tumor necrosis factor-beta biosynthetic process" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032641 ! lymphotoxin A production + +[Term] +id: GO:0042110 +name: T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] +synonym: "T lymphocyte activation" EXACT [] +synonym: "T-cell activation" EXACT [] +synonym: "T-lymphocyte activation" EXACT [] +is_a: GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0042113 +name: B cell activation +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] +synonym: "B lymphocyte activation" EXACT [] +synonym: "B-cell activation" EXACT [] +synonym: "B-lymphocyte activation" EXACT [] +is_a: GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0042116 +name: macrophage activation +namespace: biological_process +def: "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:14506301] +synonym: "macrophage polarization" EXACT [] +is_a: GO:0002274 ! myeloid leukocyte activation + +[Term] +id: GO:0042117 +name: monocyte activation +namespace: biological_process +def: "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] +is_a: GO:0002274 ! myeloid leukocyte activation + +[Term] +id: GO:0042118 +name: endothelial cell activation +namespace: biological_process +def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484] +is_a: GO:0001775 ! cell activation + +[Term] +id: GO:0042119 +name: neutrophil activation +namespace: biological_process +def: "The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] +is_a: GO:0036230 ! granulocyte activation + +[Term] +id: GO:0042120 +name: alginic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)." [ISBN:0198506732] +synonym: "alginate metabolic process" EXACT [] +synonym: "alginate metabolism" EXACT [] +synonym: "alginic acid metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0042121 +name: alginic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)." [ISBN:0198506732] +synonym: "alginate biosynthesis" EXACT [] +synonym: "alginate biosynthetic process" EXACT [] +synonym: "alginic acid anabolism" EXACT [] +synonym: "alginic acid biosynthesis" EXACT [] +synonym: "alginic acid formation" EXACT [] +synonym: "alginic acid synthesis" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0042120 ! alginic acid metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0042122 +name: alginic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)." [ISBN:0198506732] +synonym: "alginate catabolic process" EXACT [] +synonym: "alginate catabolism" EXACT [] +synonym: "alginic acid breakdown" EXACT [] +synonym: "alginic acid catabolism" EXACT [] +synonym: "alginic acid degradation" EXACT [] +is_a: GO:0042120 ! alginic acid metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0042123 +name: glucanosyltransferase activity +namespace: molecular_function +def: "Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation." [GOC:jl] +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0042124 +name: 1,3-beta-glucanosyltransferase activity +namespace: molecular_function +def: "Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation." [GOC:jl, PMID:10809732] +is_a: GO:0042123 ! glucanosyltransferase activity + +[Term] +id: GO:0042125 +name: protein galactosylation +namespace: biological_process +def: "The addition of a galactose molecule to a protein amino acid." [GOC:jl, GOC:pr] +synonym: "protein amino acid galactosylation" EXACT [GOC:bf] +is_a: GO:0006486 ! protein glycosylation + +[Term] +id: GO:0042126 +name: nitrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid." [GOC:jl] +synonym: "nitrate metabolism" EXACT [] +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:2001057 ! reactive nitrogen species metabolic process + +[Term] +id: GO:0042127 +name: regulation of cell population proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] +synonym: "regulation of cell proliferation" RELATED [] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008283 ! cell population proliferation +relationship: regulates GO:0008283 ! cell population proliferation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0042128 +name: nitrate assimilation +namespace: biological_process +def: "The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances." [GOC:das, GOC:mah, PMID:10542156, PMID:8122899] +synonym: "assimilatory nitrate reduction" EXACT [] +xref: MetaCyc:PWY-381 +is_a: GO:0042126 ! nitrate metabolic process +is_a: GO:0071941 ! nitrogen cycle metabolic process + +[Term] +id: GO:0042129 +name: regulation of T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] +synonym: "regulation of T lymphocyte proliferation" EXACT [] +synonym: "regulation of T-cell proliferation" EXACT [] +synonym: "regulation of T-lymphocyte proliferation" EXACT [] +is_a: GO:0050670 ! regulation of lymphocyte proliferation +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042098 ! T cell proliferation +relationship: regulates GO:0042098 ! T cell proliferation + +[Term] +id: GO:0042130 +name: negative regulation of T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] +synonym: "down regulation of T cell proliferation" EXACT [] +synonym: "down-regulation of T cell proliferation" EXACT [] +synonym: "downregulation of T cell proliferation" EXACT [] +synonym: "inhibition of T cell proliferation" NARROW [] +synonym: "negative regulation of T lymphocyte proliferation" EXACT [] +synonym: "negative regulation of T-cell proliferation" EXACT [] +synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +is_a: GO:0050672 ! negative regulation of lymphocyte proliferation +is_a: GO:0050868 ! negative regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042098 ! T cell proliferation +relationship: negatively_regulates GO:0042098 ! T cell proliferation + +[Term] +id: GO:0042131 +name: thiamine phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate." [PMID:197075] +synonym: "thiamin monophosphate phosphatase" EXACT [] +synonym: "thiamin phosphate phosphatase activity" EXACT [] +synonym: "ThMPase" EXACT [] +is_a: GO:0003993 ! acid phosphatase activity + +[Term] +id: GO:0042132 +name: fructose 1,6-bisphosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [EC:3.1.3.11] +synonym: "D-fructose 1,6-diphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "D-fructose-1,6-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.11] +synonym: "D-fructose-1,6-bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] +synonym: "FBPase activity" EXACT [EC:3.1.3.11] +synonym: "fructose 1,6-bisphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose 1,6-bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose 1,6-diphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose 1,6-diphosphate phosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose diphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose diphosphate phosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose-1,6-bisphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "fructose-bisphosphatase activity" BROAD [EC:3.1.3.00] +synonym: "hexose bisphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "hexose diphosphatase activity" EXACT [EC:3.1.3.11] +synonym: "hexosediphosphatase activity" BROAD [EC:3.1.3.11] +xref: EC:3.1.3.11 +xref: MetaCyc:F16BDEPHOS-RXN +xref: Reactome:R-HSA-70479 "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate" +xref: RHEA:11064 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0042133 +name: neurotransmitter metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] +subset: goslim_pir +synonym: "neurotransmitter metabolism" EXACT [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0044237 ! cellular metabolic process +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0042134 +name: rRNA primary transcript binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript." [GOC:jl] +synonym: "pre-rRNA binding" EXACT [PMID:3327689] +is_a: GO:0019843 ! rRNA binding + +[Term] +id: GO:0042135 +name: neurotransmitter catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] +subset: goslim_synapse +synonym: "neurotransmitter breakdown" EXACT [] +synonym: "neurotransmitter catabolism" EXACT [] +synonym: "neurotransmitter degradation" EXACT [] +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0042136 +name: neurotransmitter biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] +subset: goslim_synapse +synonym: "neurotransmitter anabolism" EXACT [] +synonym: "neurotransmitter biosynthesis" EXACT [] +synonym: "neurotransmitter biosynthesis and storage" BROAD [] +synonym: "neurotransmitter biosynthetic process and storage" BROAD [] +synonym: "neurotransmitter formation" EXACT [] +synonym: "neurotransmitter synthesis" EXACT [] +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0042137 +name: sequestering of neurotransmitter +namespace: biological_process +def: "The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system." [GOC:ai] +synonym: "neurotransmitter biosynthesis and storage" RELATED [] +synonym: "neurotransmitter biosynthetic process and storage" RELATED [] +synonym: "neurotransmitter retention" EXACT [] +synonym: "neurotransmitter sequestration" EXACT [] +synonym: "neurotransmitter storage" EXACT [] +synonym: "retention of neurotransmitter" EXACT [] +synonym: "sequestration of neurotransmitter" EXACT [] +synonym: "storage of neurotransmitter" EXACT [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0051235 ! maintenance of location + +[Term] +id: GO:0042138 +name: meiotic DNA double-strand break formation +namespace: biological_process +def: "The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination." [GOC:elh, GOC:jl, PMID:11529427] +is_a: GO:0061982 ! meiosis I cell cycle process +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis + +[Term] +id: GO:0042139 +name: early meiotic recombination nodule assembly +namespace: biological_process +def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene." [GOC:jl, PMID:9334324] +is_a: GO:0007146 ! meiotic recombination nodule assembly + +[Term] +id: GO:0042140 +name: late meiotic recombination nodule assembly +namespace: biological_process +def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over." [GOC:jl, PMID:9334324] +is_a: GO:0007146 ! meiotic recombination nodule assembly + +[Term] +id: GO:0042141 +name: obsolete mating pheromone exporter +namespace: molecular_function +def: "OBSOLETE. Exports diffusible peptide signals that are responsible for binding to other cells and triggering a series of responses to facilitate mating." [GOC:jl] +comment: This term was made obsolete because it is too gene product specific. +synonym: "mating pheromone exporter" EXACT [] +is_obsolete: true +consider: GO:0042626 +consider: GO:0043190 + +[Term] +id: GO:0042142 +name: obsolete heavy metal chelation +namespace: biological_process +def: "OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein." [GOC:jl, ISBN:0124325653] +comment: This term was made obsolete because it represents a molecular function and not a biological process. +synonym: "heavy metal chelation" EXACT [] +is_obsolete: true +replaced_by: GO:0046911 + +[Term] +id: GO:0042144 +name: vacuole fusion, non-autophagic +namespace: biological_process +alt_id: GO:0042145 +def: "The fusion of two vacuole membranes to form a single vacuole." [GOC:jl] +synonym: "homotypic vacuole fusion" EXACT [] +synonym: "homotypic vacuole fusion (non-autophagic)" EXACT [] +synonym: "homotypic vacuole fusion, non-autophagic" EXACT [] +synonym: "vacuole fusion (non-autophagic)" EXACT [] +is_a: GO:0097576 ! vacuole fusion + +[Term] +id: GO:0042147 +name: retrograde transport, endosome to Golgi +namespace: biological_process +def: "The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport." [GOC:jl, PMID:10873832, PMID:16936697] +synonym: "retrograde (endosome to Golgi) transport" EXACT [] +is_a: GO:0016197 ! endosomal transport +is_a: GO:0016482 ! cytosolic transport + +[Term] +id: GO:0042148 +name: strand invasion +namespace: biological_process +def: "The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:elh, PMID:10357855] +synonym: "D-loop biosynthesis" RELATED [] +synonym: "D-loop formation" RELATED [] +synonym: "displacement loop biosynthesis" RELATED [GOC:mah, GOC:vw] +synonym: "displacement loop formation" RELATED [GOC:mah, GOC:vw] +synonym: "Rad51-mediated strand invasion" EXACT [GOC:elh] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006310 ! DNA recombination + +[Term] +id: GO:0042149 +name: cellular response to glucose starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose." [GOC:jl] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0042150 +name: plasmid recombination +namespace: biological_process +def: "A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules." [GOC:mlg] +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0042151 +name: nematocyst +namespace: cellular_component +def: "An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus." [DOI:10.1139/z02-135, GOC:jl] +synonym: "cnidocyst" EXACT [] +xref: Wikipedia:Cnidocyte +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0042152 +name: RNA-mediated DNA recombination +namespace: biological_process +def: "The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele." [GOC:jl, PMID:8380627] +is_a: GO:0006310 ! DNA recombination + +[Term] +id: GO:0042153 +name: obsolete RPTP-like protein binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with proteins with similar structure/function to receptor protein tyrosine phosphatases." [GOC:jl] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "receptor protein tyrosine phosphatase-like protein binding" EXACT [] +synonym: "RPTP-like protein binding" EXACT [] +is_obsolete: true +replaced_by: GO:0005515 + +[Term] +id: GO:0042156 +name: obsolete zinc-mediated transcriptional activator activity +namespace: molecular_function +def: "OBSOLETE. Initiates or upregulates transcription in the presence of zinc." [GOC:jl] +comment: This term was obsoleted because it is defined as a Process term, i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. +synonym: "zinc-mediated transcriptional activator activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042157 +name: lipoprotein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids." [ISBN:0198506732] +synonym: "lipoprotein metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process + +[Term] +id: GO:0042158 +name: lipoprotein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids." [ISBN:0198506732] +synonym: "lipoprotein anabolism" EXACT [] +synonym: "lipoprotein biosynthesis" EXACT [] +synonym: "lipoprotein formation" EXACT [] +synonym: "lipoprotein synthesis" EXACT [] +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0042157 ! lipoprotein metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042159 +name: lipoprotein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids." [ISBN:0198506732] +synonym: "lipoprotein breakdown" EXACT [] +synonym: "lipoprotein catabolism" EXACT [] +synonym: "lipoprotein degradation" EXACT [] +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0042157 ! lipoprotein metabolic process + +[Term] +id: GO:0042160 +name: lipoprotein modification +namespace: biological_process +def: "The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:mah] +is_a: GO:0042157 ! lipoprotein metabolic process + +[Term] +id: GO:0042161 +name: lipoprotein oxidation +namespace: biological_process +def: "The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group." [GOC:mah] +is_a: GO:0042160 ! lipoprotein modification +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0042162 +name: telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end." [GOC:jl, SO:0000624] +synonym: "telomere binding" EXACT [] +synonym: "telomeric repeat binding" EXACT [] +is_a: GO:0043565 ! sequence-specific DNA binding + +[Term] +id: GO:0042163 +name: interleukin-12 beta subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the beta subunit of interleukin-12." [GOC:mah] +synonym: "CLMFp40 binding" EXACT [] +synonym: "IL-12B binding" EXACT [] +synonym: "IL-12p40 binding" EXACT [] +synonym: "NKSFp40 binding" EXACT [] +is_a: GO:0019972 ! interleukin-12 binding + +[Term] +id: GO:0042164 +name: interleukin-12 alpha subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the alpha subunit of interleukin-12." [GOC:mah] +synonym: "CLMFp35 binding" EXACT [] +synonym: "IL-12A binding" EXACT [] +synonym: "IL-12p35 binding" EXACT [] +synonym: "NKSFp35 binding" EXACT [] +is_a: GO:0019972 ! interleukin-12 binding + +[Term] +id: GO:0042165 +name: neurotransmitter binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [ISBN:0198506732] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0042166 +name: acetylcholine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] +is_a: GO:0008144 ! drug binding +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0042167 +name: heme catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring." [GOC:jl] +synonym: "haem catabolic process" EXACT [] +synonym: "haem catabolism" EXACT [] +synonym: "heme breakdown" EXACT [] +synonym: "heme catabolism" EXACT [] +synonym: "heme degradation" EXACT [] +is_a: GO:0006787 ! porphyrin-containing compound catabolic process +is_a: GO:0042168 ! heme metabolic process +is_a: GO:0046149 ! pigment catabolic process + +[Term] +id: GO:0042168 +name: heme metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring." [GOC:jl, ISBN:0124325653] +synonym: "haem metabolic process" EXACT [] +synonym: "haem metabolism" EXACT [] +synonym: "heme metabolism" EXACT [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0042169 +name: SH2 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class." [GOC:go_curators, Pfam:PF00017] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0042170 +name: plastid membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround a plastid and form the plastid envelope." [GOC:mah] +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0009526 ! plastid envelope + +[Term] +id: GO:0042171 +name: lysophosphatidic acid acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid." [GOC:ab, PMID:16369050] +synonym: "LPAAT activity" EXACT [PMID:16369050] +is_a: GO:0071617 ! lysophospholipid acyltransferase activity + +[Term] +id: GO:0042173 +name: regulation of sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore formation." [GOC:jl] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0043937 ! regulation of sporulation +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030435 ! sporulation resulting in formation of a cellular spore +relationship: regulates GO:0030435 ! sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0042174 +name: negative regulation of sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation." [GOC:go_curators] +synonym: "down regulation of sporulation" EXACT [] +synonym: "down-regulation of sporulation" EXACT [] +synonym: "downregulation of sporulation" EXACT [] +synonym: "inhibition of sporulation" NARROW [] +is_a: GO:0042173 ! regulation of sporulation resulting in formation of a cellular spore +is_a: GO:0043939 ! negative regulation of sporulation +is_a: GO:0045596 ! negative regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030435 ! sporulation resulting in formation of a cellular spore +relationship: negatively_regulates GO:0030435 ! sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0042175 +name: nuclear outer membrane-endoplasmic reticulum membrane network +namespace: cellular_component +def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] +synonym: "NE-ER continuum" RELATED [] +synonym: "NE-ER network" RELATED [] +synonym: "nuclear envelope-endoplasmic reticulum continuum" RELATED [] +synonym: "nuclear envelope-endoplasmic reticulum network" RELATED [GOC:mah] +synonym: "nuclear envelope-ER network" RELATED [] +synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah] +synonym: "nuclear membrane-ER network" EXACT [GOC:mah] +is_a: GO:0016020 ! membrane +relationship: part_of GO:0012505 ! endomembrane system + +[Term] +id: GO:0042176 +name: regulation of protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl] +synonym: "regulation of protein breakdown" EXACT [] +synonym: "regulation of protein catabolism" EXACT [] +synonym: "regulation of protein degradation" EXACT [] +is_a: GO:0009894 ! regulation of catabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030163 ! protein catabolic process +relationship: regulates GO:0030163 ! protein catabolic process + +[Term] +id: GO:0042177 +name: negative regulation of protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl, PMID:10207076] +synonym: "down regulation of protein catabolic process" EXACT [] +synonym: "down-regulation of protein catabolic process" EXACT [] +synonym: "downregulation of protein catabolic process" EXACT [] +synonym: "inhibition of protein catabolic process" NARROW [] +synonym: "negative regulation of protein breakdown" EXACT [] +synonym: "negative regulation of protein catabolism" EXACT [] +synonym: "negative regulation of protein degradation" EXACT [] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0042176 ! regulation of protein catabolic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030163 ! protein catabolic process +relationship: negatively_regulates GO:0030163 ! protein catabolic process + +[Term] +id: GO:0042178 +name: xenobiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide." [GOC:jl] +synonym: "xenobiotic breakdown" EXACT [] +synonym: "xenobiotic catabolism" EXACT [] +synonym: "xenobiotic degradation" EXACT [] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0042179 +name: nicotine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine." [GOC:sm, ISBN:0198547684] +synonym: "nicotine anabolism" EXACT [] +synonym: "nicotine biosynthesis" EXACT [] +synonym: "nicotine formation" EXACT [] +synonym: "nicotine synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0018933 ! nicotine metabolic process + +[Term] +id: GO:0042180 +name: cellular ketone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153] +subset: goslim_pir +synonym: "ketone metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0042181 +name: ketone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] +synonym: "ketone anabolism" EXACT [] +synonym: "ketone biosynthesis" EXACT [] +synonym: "ketone formation" EXACT [] +synonym: "ketone synthesis" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0042182 +name: ketone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] +synonym: "ketone breakdown" EXACT [] +synonym: "ketone catabolism" EXACT [] +synonym: "ketone degradation" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0042183 +name: formate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [ISBN:0198506732] +synonym: "formate breakdown" EXACT [] +synonym: "formate catabolism" EXACT [] +synonym: "formate degradation" EXACT [] +synonym: "formic acid catabolic process" EXACT [] +synonym: "formic acid catabolism" EXACT [] +is_a: GO:0015942 ! formate metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0042184 +name: xylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene." [GOC:go_curators] +synonym: "xylene breakdown" EXACT [] +synonym: "xylene catabolism" EXACT [] +synonym: "xylene degradation" EXACT [] +is_a: GO:0018948 ! xylene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0042185 +name: m-xylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon." [GOC:go_curators, GOC:jl] +synonym: "m-xylene breakdown" EXACT [] +synonym: "m-xylene catabolism" EXACT [] +synonym: "m-xylene degradation" EXACT [] +synonym: "meta-xylene catabolic process" EXACT [] +synonym: "meta-xylene catabolism" EXACT [] +xref: MetaCyc:PWY-142 +is_a: GO:0018949 ! m-xylene metabolic process +is_a: GO:0042184 ! xylene catabolic process + +[Term] +id: GO:0042186 +name: o-xylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon." [GOC:jl] +synonym: "o-xylene breakdown" EXACT [] +synonym: "o-xylene catabolism" EXACT [] +synonym: "o-xylene degradation" EXACT [] +synonym: "ortho-xylene catabolic process" EXACT [] +synonym: "ortho-xylene catabolism" EXACT [] +is_a: GO:0018950 ! o-xylene metabolic process +is_a: GO:0042184 ! xylene catabolic process + +[Term] +id: GO:0042187 +name: p-xylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon." [GOC:jl] +synonym: "p-xylene breakdown" EXACT [] +synonym: "p-xylene catabolism" EXACT [] +synonym: "p-xylene degradation" EXACT [] +synonym: "para-xylene catabolic process" EXACT [] +synonym: "para-xylene catabolism" EXACT [] +is_a: GO:0018951 ! p-xylene metabolic process +is_a: GO:0042184 ! xylene catabolic process + +[Term] +id: GO:0042188 +name: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide." [GOC:jl] +synonym: "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane breakdown" EXACT [] +synonym: "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolism" EXACT [] +synonym: "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane degradation" EXACT [] +synonym: "DDT catabolic process" EXACT [] +synonym: "DDT catabolism" EXACT [] +is_a: GO:0018977 ! 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042205 ! chlorinated hydrocarbon catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046701 ! insecticide catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0042189 +name: vanillin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods." [GOC:jl] +synonym: "vanillic aldehyde biosynthesis" EXACT [] +synonym: "vanillic aldehyde biosynthetic process" EXACT [] +synonym: "vanillin anabolism" EXACT [] +synonym: "vanillin biosynthesis" EXACT [] +synonym: "vanillin formation" EXACT [] +synonym: "vanillin synthesis" EXACT [] +is_a: GO:0018982 ! vanillin metabolic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0042190 +name: vanillin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods." [GOC:jl] +synonym: "vanillic aldehyde catabolic process" EXACT [] +synonym: "vanillic aldehyde catabolism" EXACT [] +synonym: "vanillin breakdown" EXACT [] +synonym: "vanillin catabolism" EXACT [] +synonym: "vanillin degradation" EXACT [] +is_a: GO:0018982 ! vanillin metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0042191 +name: methylmercury metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species." [GOC:ai] +synonym: "methylmercury metabolism" EXACT [] +is_a: GO:0018941 ! organomercury metabolic process + +[Term] +id: GO:0042192 +name: methylmercury biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal." [GOC:ai] +synonym: "methylmercury anabolism" EXACT [] +synonym: "methylmercury biosynthesis" EXACT [] +synonym: "methylmercury formation" EXACT [] +synonym: "methylmercury synthesis" EXACT [] +is_a: GO:0042191 ! methylmercury metabolic process +is_a: GO:0046414 ! organomercury biosynthetic process + +[Term] +id: GO:0042193 +name: methylmercury catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal." [GOC:ai] +synonym: "methylmercury breakdown" EXACT [] +synonym: "methylmercury catabolism" EXACT [] +synonym: "methylmercury degradation" EXACT [] +is_a: GO:0042191 ! methylmercury metabolic process +is_a: GO:0046413 ! organomercury catabolic process + +[Term] +id: GO:0042194 +name: quinate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid." [GOC:go_curators] +synonym: "quinate anabolism" EXACT [] +synonym: "quinate biosynthesis" EXACT [] +synonym: "quinate formation" EXACT [] +synonym: "quinate synthesis" EXACT [] +synonym: "quinic acid biosynthesis" EXACT [] +synonym: "quinic acid biosynthetic process" EXACT [] +is_a: GO:0019630 ! quinate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0042195 +name: aerobic gallate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen." [GOC:jl] +synonym: "aerobic gallate breakdown" EXACT [] +synonym: "aerobic gallate catabolism" EXACT [] +synonym: "aerobic gallate degradation" EXACT [] +synonym: "aerobic gallic acid catabolic process" EXACT [] +synonym: "aerobic gallic acid catabolism" EXACT [] +is_a: GO:0019396 ! gallate catabolic process + +[Term] +id: GO:0042196 +name: chlorinated hydrocarbon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorinated hydrocarbons, any hydrocarbon with one or more chlorine atoms attached to it." [GOC:ai] +synonym: "chlorinated hydrocarbon metabolism" EXACT [] +is_a: GO:0042197 ! halogenated hydrocarbon metabolic process + +[Term] +id: GO:0042197 +name: halogenated hydrocarbon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it. Halogens include fluorine, chlorine, bromine and iodine." [GOC:ai] +synonym: "halogenated hydrocarbon metabolism" EXACT [] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0042198 +name: nylon metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids." [UniProtKB-KW:KW-0549] +synonym: "nylon metabolism" EXACT [] +is_a: GO:0006805 ! xenobiotic metabolic process + +[Term] +id: GO:0042199 +name: cyanuric acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives." [UM-BBD_pathwayID:cya] +synonym: "cyanuric acid metabolism" EXACT [] +is_a: GO:0018965 ! s-triazine compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042200 +name: cyanuric acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides." [UM-BBD_pathwayID:cya] +synonym: "cyanuric acid breakdown" EXACT [] +synonym: "cyanuric acid catabolism" EXACT [] +synonym: "cyanuric acid degradation" EXACT [] +xref: UM-BBD_pathwayID:cya +is_a: GO:0042199 ! cyanuric acid metabolic process +is_a: GO:0042204 ! s-triazine compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0042201 +name: N-cyclopropylmelamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide." [UM-BBD_pathwayID:cpm] +synonym: "cyromazine metabolic process" EXACT [] +synonym: "cyromazine metabolism" EXACT [] +synonym: "N-cyclopropylmelamine metabolism" EXACT [] +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0018965 ! s-triazine compound metabolic process + +[Term] +id: GO:0042202 +name: N-cyclopropylmelamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide." [UM-BBD_pathwayID:cpm] +synonym: "cyromazine catabolic process" EXACT [] +synonym: "cyromazine catabolism" EXACT [] +synonym: "N-cyclopropylmelamine breakdown" EXACT [] +synonym: "N-cyclopropylmelamine catabolism" EXACT [] +synonym: "N-cyclopropylmelamine degradation" EXACT [] +xref: UM-BBD_pathwayID:cpm +is_a: GO:0042201 ! N-cyclopropylmelamine metabolic process +is_a: GO:0042204 ! s-triazine compound catabolic process +is_a: GO:0046701 ! insecticide catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound + +[Term] +id: GO:0042203 +name: toluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products." [GOC:go_curators] +synonym: "toluene breakdown" EXACT [] +synonym: "toluene catabolism" EXACT [] +synonym: "toluene degradation" EXACT [] +is_a: GO:0018970 ! toluene metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0042204 +name: s-triazine compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms." [UM-BBD_pathwayID:tria] +synonym: "s-triazine compound breakdown" EXACT [] +synonym: "s-triazine compound catabolism" EXACT [] +synonym: "s-triazine compound degradation" EXACT [] +xref: UM-BBD_pathwayID:tria +is_a: GO:0018965 ! s-triazine compound metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042205 +name: chlorinated hydrocarbon catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, any hydrocarbon with one or more chlorine atoms attached to it." [GOC:ai] +synonym: "chlorinated hydrocarbon breakdown" EXACT [] +synonym: "chlorinated hydrocarbon catabolism" EXACT [] +synonym: "chlorinated hydrocarbon degradation" EXACT [] +is_a: GO:0042196 ! chlorinated hydrocarbon metabolic process +is_a: GO:0042206 ! halogenated hydrocarbon catabolic process + +[Term] +id: GO:0042206 +name: halogenated hydrocarbon catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it." [GOC:ai] +synonym: "halogenated hydrocarbon breakdown" EXACT [] +synonym: "halogenated hydrocarbon catabolism" EXACT [] +synonym: "halogenated hydrocarbon degradation" EXACT [] +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042197 ! halogenated hydrocarbon metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0042207 +name: styrene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene." [GOC:jl] +synonym: "styrene breakdown" EXACT [] +synonym: "styrene catabolism" EXACT [] +synonym: "styrene degradation" EXACT [] +xref: UM-BBD_pathwayID:sty +is_a: GO:0018966 ! styrene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0042208 +name: propylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining." [GOC:jl] +synonym: "propylene breakdown" EXACT [] +synonym: "propylene catabolism" EXACT [] +synonym: "propylene degradation" EXACT [] +xref: UM-BBD_pathwayID:pro +is_a: GO:0018964 ! propylene metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0043451 ! alkene catabolic process + +[Term] +id: GO:0042209 +name: orcinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants." [GOC:jl] +synonym: "orcin catabolic process" EXACT [] +synonym: "orcin catabolism" EXACT [] +synonym: "orcinol breakdown" EXACT [] +synonym: "orcinol catabolism" EXACT [] +synonym: "orcinol degradation" EXACT [] +xref: UM-BBD_pathwayID:orc +is_a: GO:0018940 ! orcinol metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process + +[Term] +id: GO:0042210 +name: octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter." [GOC:jl] +synonym: "catabolic process of octamethylcyclotetrasiloxane to DMSD" EXACT [] +synonym: "catabolism of octamethylcyclotetrasiloxane to DMSD" EXACT [] +synonym: "octamethylcyclotetrasiloxane breakdown to dimethylsilanediol" EXACT [] +synonym: "octamethylcyclotetrasiloxane degradation to dimethylsilanediol" EXACT [] +xref: UM-BBD_pathwayID:osi +is_a: GO:0018947 ! anaerobic organosilicon metabolic process +is_a: GO:0046454 ! dimethylsilanediol metabolic process +is_a: GO:0046517 ! octamethylcyclotetrasiloxane catabolic process + +[Term] +id: GO:0042211 +name: dimethylsilanediol catabolic process +namespace: biological_process +def: "The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products." [GOC:jl] +synonym: "catabolic process of DMSD" EXACT [] +synonym: "catabolism of DMSD" EXACT [] +synonym: "degradation of dimethylsilanediol" EXACT [] +synonym: "dimethylsilanediol breakdown" EXACT [] +synonym: "dimethylsilanediol catabolism" EXACT [] +synonym: "dimethylsilanediol degradation" EXACT [] +is_a: GO:0018946 ! aerobic organosilicon metabolic process +is_a: GO:0046454 ! dimethylsilanediol metabolic process +is_a: GO:0046455 ! organosilicon catabolic process + +[Term] +id: GO:0042212 +name: cresol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote." [UM-BBD_pathwayID:mcr] +synonym: "cresol metabolism" EXACT [] +synonym: "hydroxytoluene metabolic process" EXACT [] +synonym: "hydroxytoluene metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process + +[Term] +id: GO:0042213 +name: m-cresol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol." [GOC:jl] +synonym: "3-hydroxytoluene catabolic process" EXACT [] +synonym: "3-hydroxytoluene catabolism" EXACT [] +synonym: "m-cresol breakdown" EXACT [] +synonym: "m-cresol catabolism" EXACT [] +synonym: "m-cresol degradation" EXACT [] +synonym: "meta-cresol catabolic process" EXACT [] +synonym: "meta-cresol catabolism" EXACT [] +xref: MetaCyc:M-CRESOL-DEGRADATION-PWY +xref: UM-BBD_pathwayID:mcr +is_a: GO:0018925 ! m-cresol metabolic process +is_a: GO:0046199 ! cresol catabolic process + +[Term] +id: GO:0042214 +name: terpene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups." [GOC:curators] +synonym: "terpene metabolism" EXACT [] +is_a: GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0042215 +name: anaerobic phenol-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen." [PMID:12697029] +synonym: "anaerobic phenol-containing compound metabolism" EXACT [] +xref: UM-BBD_pathwayID:phe +is_a: GO:0018958 ! phenol-containing compound metabolic process + +[Term] +id: GO:0042216 +name: phenanthrene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon." [GOC:jl] +synonym: "phenanthrene breakdown" EXACT [] +synonym: "phenanthrene catabolism" EXACT [] +synonym: "phenanthrene degradation" EXACT [] +xref: UM-BBD_pathwayID:phe +is_a: GO:0018955 ! phenanthrene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0042217 +name: 1-aminocyclopropane-1-carboxylate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants." [GOC:go_curators] +synonym: "1-aminocyclopropane-1-carboxylate breakdown" EXACT [] +synonym: "1-aminocyclopropane-1-carboxylate catabolism" EXACT [] +synonym: "1-aminocyclopropane-1-carboxylate degradation" EXACT [] +is_a: GO:0018871 ! 1-aminocyclopropane-1-carboxylate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0042218 +name: 1-aminocyclopropane-1-carboxylate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants." [GOC:go_curators] +synonym: "1-aminocyclopropane-1-carboxylate anabolism" EXACT [] +synonym: "1-aminocyclopropane-1-carboxylate biosynthesis" EXACT [] +synonym: "1-aminocyclopropane-1-carboxylate formation" EXACT [] +synonym: "1-aminocyclopropane-1-carboxylate synthesis" EXACT [] +is_a: GO:0018871 ! 1-aminocyclopropane-1-carboxylate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0042219 +name: cellular modified amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents." [GOC:ai] +synonym: "amino acid derivative catabolic process" EXACT [] +synonym: "cellular amino acid derivative breakdown" EXACT [] +synonym: "cellular amino acid derivative catabolic process" EXACT [] +synonym: "cellular amino acid derivative catabolism" EXACT [] +synonym: "cellular amino acid derivative degradation" EXACT [] +synonym: "cellular modified amino acid breakdown" EXACT [GOC:mah] +synonym: "cellular modified amino acid catabolism" EXACT [GOC:mah] +synonym: "cellular modified amino acid degradation" EXACT [GOC:mah] +synonym: "modified amino acid catabolic process" EXACT [GOC:mah] +synonym: "modified amino acid catabolism" EXACT [GOC:mah] +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042220 +name: response to cocaine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant." [GOC:ef, GOC:jl] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043279 ! response to alkaloid +is_a: GO:0072347 ! response to anesthetic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0042221 +name: response to chemical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_drosophila +subset: goslim_metagenomics +subset: goslim_plant +subset: goslim_yeast +synonym: "response to chemical stimulus" EXACT [GOC:dos] +synonym: "response to chemical substance" EXACT [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0042222 +name: interleukin-1 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-1, an interleukin produced mainly by activated macrophages. It is involved in the inflammatory response, and is identified as an endogenous pyrogen." [GOC:jl, ISBN:0198506732] +synonym: "IL-1 biosynthesis" EXACT [] +synonym: "IL-1 biosynthetic process" EXACT [] +synonym: "interleukin-1 anabolism" EXACT [] +synonym: "interleukin-1 biosynthesis" EXACT [] +synonym: "interleukin-1 formation" EXACT [] +synonym: "interleukin-1 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0042223 +name: interleukin-3 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] +synonym: "IL-3 biosynthesis" EXACT [] +synonym: "IL-3 biosynthetic process" EXACT [] +synonym: "interleukin-3 anabolism" EXACT [] +synonym: "interleukin-3 biosynthesis" EXACT [] +synonym: "interleukin-3 formation" EXACT [] +synonym: "interleukin-3 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032632 ! interleukin-3 production + +[Term] +id: GO:0042225 +name: interleukin-5 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] +synonym: "IL-5 biosynthesis" EXACT [] +synonym: "IL-5 biosynthetic process" EXACT [] +synonym: "interleukin-5 anabolism" EXACT [] +synonym: "interleukin-5 biosynthesis" EXACT [] +synonym: "interleukin-5 formation" EXACT [] +synonym: "interleukin-5 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032634 ! interleukin-5 production + +[Term] +id: GO:0042226 +name: interleukin-6 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] +synonym: "IL-6 biosynthesis" EXACT [] +synonym: "IL-6 biosynthetic process" EXACT [] +synonym: "interleukin-6 anabolism" EXACT [] +synonym: "interleukin-6 biosynthesis" EXACT [] +synonym: "interleukin-6 formation" EXACT [] +synonym: "interleukin-6 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032635 ! interleukin-6 production + +[Term] +id: GO:0042227 +name: interleukin-7 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] +synonym: "IL-7 biosynthesis" EXACT [] +synonym: "IL-7 biosynthetic process" EXACT [] +synonym: "interleukin-7 anabolism" EXACT [] +synonym: "interleukin-7 biosynthesis" EXACT [] +synonym: "interleukin-7 formation" EXACT [] +synonym: "interleukin-7 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032636 ! interleukin-7 production + +[Term] +id: GO:0042228 +name: interleukin-8 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] +synonym: "IL-8 biosynthesis" EXACT [] +synonym: "IL-8 biosynthetic process" EXACT [] +synonym: "interleukin-8 anabolism" EXACT [] +synonym: "interleukin-8 biosynthesis" EXACT [] +synonym: "interleukin-8 formation" EXACT [] +synonym: "interleukin-8 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032637 ! interleukin-8 production + +[Term] +id: GO:0042229 +name: interleukin-9 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] +synonym: "IL-9 biosynthesis" EXACT [] +synonym: "IL-9 biosynthetic process" EXACT [] +synonym: "interleukin-9 anabolism" EXACT [] +synonym: "interleukin-9 biosynthesis" EXACT [] +synonym: "interleukin-9 formation" EXACT [] +synonym: "interleukin-9 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032638 ! interleukin-9 production + +[Term] +id: GO:0042230 +name: interleukin-11 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] +synonym: "IL-11 biosynthesis" EXACT [] +synonym: "IL-11 biosynthetic process" EXACT [] +synonym: "interleukin-11 anabolism" EXACT [] +synonym: "interleukin-11 biosynthesis" EXACT [] +synonym: "interleukin-11 formation" EXACT [] +synonym: "interleukin-11 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032614 ! interleukin-11 production + +[Term] +id: GO:0042231 +name: interleukin-13 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] +synonym: "IL-13 biosynthesis" EXACT [] +synonym: "IL-13 biosynthetic process" EXACT [] +synonym: "interleukin-13 anabolism" EXACT [] +synonym: "interleukin-13 biosynthesis" EXACT [] +synonym: "interleukin-13 formation" EXACT [] +synonym: "interleukin-13 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032616 ! interleukin-13 production + +[Term] +id: GO:0042232 +name: interleukin-14 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] +synonym: "IL-14 biosynthesis" EXACT [] +synonym: "IL-14 biosynthetic process" EXACT [] +synonym: "interleukin-14 anabolism" EXACT [] +synonym: "interleukin-14 biosynthesis" EXACT [] +synonym: "interleukin-14 formation" EXACT [] +synonym: "interleukin-14 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032617 ! interleukin-14 production + +[Term] +id: GO:0042233 +name: interleukin-15 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] +synonym: "IL-15 biosynthesis" EXACT [] +synonym: "IL-15 biosynthetic process" EXACT [] +synonym: "interleukin-15 anabolism" EXACT [] +synonym: "interleukin-15 biosynthesis" EXACT [] +synonym: "interleukin-15 formation" EXACT [] +synonym: "interleukin-15 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032618 ! interleukin-15 production + +[Term] +id: GO:0042234 +name: interleukin-16 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] +synonym: "IL-16 biosynthesis" EXACT [] +synonym: "IL-16 biosynthetic process" EXACT [] +synonym: "interleukin-16 anabolism" EXACT [] +synonym: "interleukin-16 biosynthesis" EXACT [] +synonym: "interleukin-16 formation" EXACT [] +synonym: "interleukin-16 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032619 ! interleukin-16 production + +[Term] +id: GO:0042235 +name: interleukin-17 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:go_curators] +synonym: "IL-17 biosynthesis" EXACT [] +synonym: "IL-17 biosynthetic process" EXACT [] +synonym: "interleukin-17 anabolism" EXACT [] +synonym: "interleukin-17 biosynthesis" EXACT [] +synonym: "interleukin-17 formation" EXACT [] +synonym: "interleukin-17 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032620 ! interleukin-17 production + +[Term] +id: GO:0042236 +name: interleukin-19 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] +synonym: "IL-19 biosynthesis" EXACT [] +synonym: "IL-19 biosynthetic process" EXACT [] +synonym: "interleukin-19 anabolism" EXACT [] +synonym: "interleukin-19 biosynthesis" EXACT [] +synonym: "interleukin-19 formation" EXACT [] +synonym: "interleukin-19 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032622 ! interleukin-19 production + +[Term] +id: GO:0042237 +name: interleukin-20 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] +synonym: "IL-20 biosynthesis" EXACT [] +synonym: "IL-20 biosynthetic process" EXACT [] +synonym: "interleukin-20 anabolism" EXACT [] +synonym: "interleukin-20 biosynthesis" EXACT [] +synonym: "interleukin-20 formation" EXACT [] +synonym: "interleukin-20 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032624 ! interleukin-20 production + +[Term] +id: GO:0042238 +name: interleukin-21 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] +synonym: "IL-21 biosynthesis" EXACT [] +synonym: "IL-21 biosynthetic process" EXACT [] +synonym: "interleukin-21 anabolism" EXACT [] +synonym: "interleukin-21 biosynthesis" EXACT [] +synonym: "interleukin-21 formation" EXACT [] +synonym: "interleukin-21 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032625 ! interleukin-21 production + +[Term] +id: GO:0042239 +name: interleukin-22 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] +synonym: "IL-22 biosynthesis" EXACT [] +synonym: "IL-22 biosynthetic process" EXACT [] +synonym: "interleukin-22 anabolism" EXACT [] +synonym: "interleukin-22 biosynthesis" EXACT [] +synonym: "interleukin-22 formation" EXACT [] +synonym: "interleukin-22 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032626 ! interleukin-22 production + +[Term] +id: GO:0042240 +name: interleukin-23 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] +synonym: "IL-23 biosynthesis" EXACT [] +synonym: "IL-23 biosynthetic process" EXACT [] +synonym: "interleukin-23 anabolism" EXACT [] +synonym: "interleukin-23 biosynthesis" EXACT [] +synonym: "interleukin-23 formation" EXACT [] +synonym: "interleukin-23 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032627 ! interleukin-23 production + +[Term] +id: GO:0042241 +name: interleukin-18 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] +synonym: "IL-18 biosynthesis" EXACT [] +synonym: "IL-18 biosynthetic process" EXACT [] +synonym: "interleukin-18 anabolism" EXACT [] +synonym: "interleukin-18 biosynthesis" EXACT [] +synonym: "interleukin-18 formation" EXACT [] +synonym: "interleukin-18 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032621 ! interleukin-18 production + +[Term] +id: GO:0042242 +name: cobyrinic acid a,c-diamide synthase activity +namespace: molecular_function +alt_id: GO:0043775 +def: "Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide." [PMID:2172209, RHEA:26289] +synonym: "CobB" NARROW [] +synonym: "cobyrinate a c diamide synthase activity" EXACT [] +synonym: "cobyrinate a c-diamide synthase activity" EXACT [] +synonym: "cobyrinate a,c diamide synthase activity" EXACT [] +synonym: "cobyrinate a,c-diamide synthase activity" EXACT [] +xref: EC:6.3.5.11 +xref: RHEA:26289 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0042243 +name: asexual spore wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species." [GOC:mah] +synonym: "asexual spore wall formation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0042244 ! spore wall assembly +relationship: part_of GO:0030436 ! asexual sporulation + +[Term] +id: GO:0042244 +name: spore wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore." [GOC:mah, GOC:pg] +synonym: "spore coat biosynthesis" EXACT [] +synonym: "spore coat biosynthetic process" EXACT [] +synonym: "spore wall formation" EXACT [] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0070726 ! cell wall assembly +relationship: part_of GO:0070590 ! spore wall biogenesis + +[Term] +id: GO:0042245 +name: RNA repair +namespace: biological_process +def: "Any process that results in the repair of damaged RNA." [PMID:11000254, PMID:11070075, UniProtKB-KW:KW-0692] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0042246 +name: tissue regeneration +namespace: biological_process +def: "The regrowth of lost or destroyed tissues." [GOC:curators] +is_a: GO:0009888 ! tissue development +is_a: GO:0031099 ! regeneration +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0042247 +name: establishment of planar polarity of follicular epithelium +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates." [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb] +is_a: GO:0001736 ! establishment of planar polarity +is_a: GO:0016334 ! establishment or maintenance of polarity of follicular epithelium + +[Term] +id: GO:0042248 +name: maintenance of polarity of follicular epithelium +namespace: biological_process +def: "The maintenance of an established polarized follicular epithelial sheet." [GOC:bf] +is_a: GO:0016334 ! establishment or maintenance of polarity of follicular epithelium + +[Term] +id: GO:0042249 +name: establishment of planar polarity of embryonic epithelium +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates." [GOC:ascb_2009, GOC:dph, GOC:jl, GOC:tb] +is_a: GO:0001736 ! establishment of planar polarity + +[Term] +id: GO:0042250 +name: maintenance of polarity of embryonic epithelium +namespace: biological_process +def: "The maintenance of an established polarized embryonic epithelial sheet." [GOC:jl] +is_a: GO:0016332 ! establishment or maintenance of polarity of embryonic epithelium + +[Term] +id: GO:0042251 +name: maintenance of polarity of larval imaginal disc epithelium +namespace: biological_process +def: "The maintenance of an established polarized larval imaginal disc epithelium." [GOC:jl] +is_a: GO:0016336 ! establishment or maintenance of polarity of larval imaginal disc epithelium + +[Term] +id: GO:0042252 +name: establishment of planar polarity of larval imaginal disc epithelium +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates." [GOC:jl] +is_a: GO:0001736 ! establishment of planar polarity + +[Term] +id: GO:0042253 +name: granulocyte macrophage colony-stimulating factor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor, cytokines that act in hemopoiesis by controlling the production, differentiation, and function of two related white cell populations, granulocytes and monocytes-macrophages." [GOC:jl, ISBN:0198506732] +synonym: "GM-CSF biosynthesis" EXACT [] +synonym: "GM-CSF biosynthetic process" EXACT [] +synonym: "GMC-SF biosynthesis" EXACT [] +synonym: "GMC-SF biosynthetic process" EXACT [] +synonym: "granulocyte macrophage colony stimulating factor biosynthetic process" EXACT [] +synonym: "granulocyte macrophage colony-stimulating factor anabolism" EXACT [] +synonym: "granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] +synonym: "granulocyte macrophage colony-stimulating factor formation" EXACT [] +synonym: "granulocyte macrophage colony-stimulating factor synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032604 ! granulocyte macrophage colony-stimulating factor production + +[Term] +id: GO:0042254 +name: ribosome biogenesis +namespace: biological_process +alt_id: GO:0007046 +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +synonym: "ribosome biogenesis and assembly" EXACT [] +is_a: GO:0022613 ! ribonucleoprotein complex biogenesis + +[Term] +id: GO:0042255 +name: ribosome assembly +namespace: biological_process +alt_id: GO:0042257 +def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma] +subset: goslim_yeast +synonym: "ribosomal subunit assembly" NARROW [GOC:mah, GOC:vw] +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0042254 ! ribosome biogenesis + +[Term] +id: GO:0042256 +name: mature ribosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome." [GOC:ma] +is_a: GO:0042255 ! ribosome assembly + +[Term] +id: GO:0042258 +name: molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide +namespace: biological_process +def: "The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide." [PDB:1EU1, PMID:8658132, RESID:AA0319] +xref: RESID:AA0319 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex + +[Term] +id: GO:0042259 +name: peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine +namespace: biological_process +def: "The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12." [GOC:jsg, RESID:AA0320] +synonym: "peptidyl-L-beta-methylthioasparagine anabolism from peptidyl-asparagine" EXACT [] +synonym: "peptidyl-L-beta-methylthioasparagine formation from peptidyl-asparagine" EXACT [] +synonym: "peptidyl-L-beta-methylthioasparagine synthesis from peptidyl-asparagine" EXACT [] +xref: RESID:AA0320 +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0042262 +name: DNA protection +namespace: biological_process +def: "Any process in which DNA is protected from damage by, for example, oxidative stress." [GOC:jl] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0031668 ! cellular response to extracellular stimulus +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0042263 +name: neuropeptide F receptor activity +namespace: molecular_function +def: "Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa." [GOC:bf, GOC:ma, PMID:21440021] +comment: Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related. +synonym: "NPF receptor activity" EXACT [PMID:21440021] +is_a: GO:0008188 ! neuropeptide receptor activity + +[Term] +id: GO:0042264 +name: peptidyl-aspartic acid hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid." [GOC:mah] +synonym: "peptidyl-aspartic acid/asparagine hydroxylation" BROAD [] +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0042265 +name: peptidyl-asparagine hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine." [GOC:mah] +synonym: "peptidyl-aspartic acid/asparagine hydroxylation" BROAD [] +is_a: GO:0018126 ! protein hydroxylation +is_a: GO:0018196 ! peptidyl-asparagine modification + +[Term] +id: GO:0042267 +name: natural killer cell mediated cytotoxicity +namespace: biological_process +def: "The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, GOC:pr] +comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. +synonym: "killer activity" RELATED [] +synonym: "natural killer cell mediated cell death" EXACT [] +synonym: "natural killer cell mediated cell killing" EXACT [] +synonym: "natural killer cell mediated cytolysis" RELATED [] +synonym: "natural killer-cell mediated cytolysis" RELATED [] +synonym: "NK cell mediated cell death" EXACT [] +synonym: "NK cell mediated cell killing" EXACT [] +synonym: "NK cell mediated cytolysis" RELATED [] +synonym: "NK cell mediated cytotoxicity" EXACT [] +is_a: GO:0001909 ! leukocyte mediated cytotoxicity +is_a: GO:0002228 ! natural killer cell mediated immunity + +[Term] +id: GO:0042268 +name: regulation of cytolysis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm." [GOC:jl, GOC:mtg_apoptosis] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019835 ! cytolysis +relationship: regulates GO:0019835 ! cytolysis + +[Term] +id: GO:0042269 +name: regulation of natural killer cell mediated cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "regulation of natural killer cell mediated cell death" EXACT [] +synonym: "regulation of natural killer cell mediated cell killing" EXACT [] +synonym: "regulation of natural killer cell mediated cytolysis" RELATED [] +synonym: "regulation of natural killer-cell mediated cytolysis" RELATED [] +synonym: "regulation of NK cell mediated cell death" EXACT [] +synonym: "regulation of NK cell mediated cell killing" EXACT [] +synonym: "regulation of NK cell mediated cytolysis" RELATED [] +synonym: "regulation of NK cell mediated cytotoxicity" RELATED [] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002715 ! regulation of natural killer cell mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042267 ! natural killer cell mediated cytotoxicity +relationship: regulates GO:0042267 ! natural killer cell mediated cytotoxicity + +[Term] +id: GO:0042270 +name: protection from natural killer cell mediated cytotoxicity +namespace: biological_process +def: "The process of protecting a cell from natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "protection from natural killer cell mediated cell death" EXACT [] +synonym: "protection from natural killer cell mediated cell killing" EXACT [] +synonym: "protection from natural killer cell mediated cytolysis" RELATED [] +synonym: "protection from NK cell mediated cell death" EXACT [] +synonym: "protection from NK cell mediated cell killing" EXACT [] +synonym: "protection from NK cell mediated cytolysis" RELATED [] +synonym: "protection from NK cell mediated cytotoxicity" EXACT [] +is_a: GO:0045953 ! negative regulation of natural killer cell mediated cytotoxicity + +[Term] +id: GO:0042271 +name: susceptibility to natural killer cell mediated cytotoxicity +namespace: biological_process +def: "The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +comment: Note that this term is intended for cell-surface molecules on a target cell which interact with activating receptors on a natural killer cell to promote natural killer cell mediated cytotoxicity. +synonym: "susceptibility to natural killer cell mediated cell death" EXACT [] +synonym: "susceptibility to natural killer cell mediated cell killing" EXACT [] +synonym: "susceptibility to natural killer cell mediated cytolysis" RELATED [] +synonym: "susceptibility to NK cell mediated cell death" EXACT [] +synonym: "susceptibility to NK cell mediated cell killing" EXACT [] +synonym: "susceptibility to NK cell mediated cytolysis" EXACT [] +synonym: "susceptibility to NK cell mediated cytotoxicity" EXACT [] +is_a: GO:0045954 ! positive regulation of natural killer cell mediated cytotoxicity + +[Term] +id: GO:0042272 +name: nuclear RNA export factor complex +namespace: cellular_component +def: "A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm." [PMID:11780633] +synonym: "Mex67-Mtr2 complex" EXACT [] +synonym: "NXF1-NXT1 complex" EXACT [] +synonym: "TAP-p15 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0042273 +name: ribosomal large subunit biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis." [GOC:jl] +subset: goslim_yeast +synonym: "ribosomal large subunit biogenesis and assembly" EXACT [] +is_a: GO:0022613 ! ribonucleoprotein complex biogenesis +relationship: part_of GO:0042254 ! ribosome biogenesis + +[Term] +id: GO:0042274 +name: ribosomal small subunit biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis." [GOC:jl] +subset: goslim_yeast +synonym: "ribosomal small subunit biogenesis and assembly" EXACT [] +is_a: GO:0022613 ! ribonucleoprotein complex biogenesis +relationship: part_of GO:0042254 ! ribosome biogenesis + +[Term] +id: GO:0042275 +name: error-free postreplication DNA repair +namespace: biological_process +def: "The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate." [GOC:elh, GOC:jl, PMID:11459630] +comment: Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication. +synonym: "error-free PRR" EXACT [] +synonym: "error-free replication restart" RELATED [] +is_a: GO:0006301 ! postreplication repair + +[Term] +id: GO:0042276 +name: error-prone translesion synthesis +namespace: biological_process +def: "The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites." [GOC:elh, GOC:jl, PMID:11485998] +synonym: "error-prone postreplication DNA repair" RELATED [GOC:elh] +synonym: "mutagenic postreplication DNA repair" RELATED [GOC:elh] +synonym: "mutagenic PRR" EXACT [] +is_a: GO:0019985 ! translesion synthesis + +[Term] +id: GO:0042277 +name: peptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds." [GOC:jl] +subset: goslim_chembl +subset: goslim_pir +is_a: GO:0033218 ! amide binding + +[Term] +id: GO:0042278 +name: purine nucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:jl, ISBN:0140512713] +synonym: "purine metabolic process" BROAD [] +synonym: "purine metabolism" BROAD [] +synonym: "purine nucleoside metabolism" EXACT [] +is_a: GO:0009116 ! nucleoside metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0042279 +name: nitrite reductase (cytochrome, ammonia-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+." [EC:1.7.2.2] +synonym: "ammonia:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.7.2.2] +synonym: "cytochrome c nitrite reductase activity" EXACT [] +synonym: "cytochrome c552 activity" NARROW [EC:1.7.2.2] +synonym: "multiheme nitrite reductase activity" EXACT [] +synonym: "nitrite reductase (cytochrome; ammonia-forming)" EXACT [EC:1.7.2.2] +xref: EC:1.7.2.2 +xref: MetaCyc:1.7.2.2-RXN +xref: Wikipedia:Cytochrome_c_nitrite_reductase +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor +is_a: GO:0098809 ! nitrite reductase activity + +[Term] +id: GO:0042280 +name: obsolete cell surface antigen activity, host-interacting +namespace: molecular_function +def: "OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition." [GOC:mb] +comment: This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. +synonym: "cell surface antigen activity, host-interacting" EXACT [] +is_obsolete: true +consider: GO:0044403 +consider: GO:0046789 + +[Term] +id: GO:0042281 +name: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol." [GOC:al, MetaCyc:RXN-5470] +synonym: "dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] +xref: EC:2.4.1.267 +xref: MetaCyc:RXN-5470 +is_a: GO:0046527 ! glucosyltransferase activity +relationship: part_of GO:0006490 ! oligosaccharide-lipid intermediate biosynthetic process + +[Term] +id: GO:0042282 +name: hydroxymethylglutaryl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH." [EC:1.1.1.88, RHEA:14833] +synonym: "(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)" EXACT [EC:1.1.1.88] +synonym: "3-hydroxy-3-methylglutaryl coenzyme A reductase activity" EXACT [EC:1.1.1.88] +synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.88] +synonym: "beta-hydroxy-beta-methylglutaryl CoA-reductase activity" BROAD [EC:1.1.1.88] +synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity" BROAD [EC:1.1.1.88] +synonym: "HMG-CoA reductase activity" BROAD [EC:1.1.1.88] +synonym: "hydroxymethylglutaryl coenzyme A reductase activity" BROAD [EC:1.1.1.88] +synonym: "hydroxymethylglutaryl-CoA reductase (NADH) activity" EXACT [EC:1.1.1.88] +xref: EC:1.1.1.88 +xref: KEGG_REACTION:R02081 +xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN +xref: RHEA:14833 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0042283 +name: dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol." [MetaCyc:RXN-5471, PMID:12480927] +synonym: "dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] +xref: EC:2.4.1.265 +xref: MetaCyc:RXN-5471 +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0042284 +name: sphingolipid delta-4 desaturase activity +namespace: molecular_function +def: "Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid." [PMID:12417141] +synonym: "delta-4 sphingolipid desaturase activity" EXACT [] +xref: Reactome:R-HSA-428259 "dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O" +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0042285 +name: xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0042286 +name: glutamate-1-semialdehyde 2,1-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate." [EC:5.4.3.8, RHEA:14265] +synonym: "(S)-4-amino-5-oxopentanoate 4,5-aminomutase activity" EXACT [EC:5.4.3.8] +synonym: "glutamate-1-semialdehyde aminotransferase activity" EXACT [EC:5.4.3.8] +xref: EC:5.4.3.8 +xref: KEGG_REACTION:R02272 +xref: MetaCyc:GSAAMINOTRANS-RXN +xref: RHEA:14265 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0042287 +name: MHC protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] +comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein, for this also annotate to 'peptide antigen binding ; GO:0042605' or one of its children. +synonym: "major histocompatibility complex binding" EXACT [] +synonym: "major histocompatibility complex ligand" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042288 +name: MHC class I protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] +comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children. +synonym: "alpha-beta T cell receptor activity" RELATED [] +synonym: "gamma-delta T cell receptor activity" RELATED [] +synonym: "major histocompatibility complex class I binding" EXACT [] +synonym: "major histocompatibility complex class I ligand" NARROW [] +synonym: "T cell receptor activity" RELATED [] +is_a: GO:0042287 ! MHC protein binding + +[Term] +id: GO:0042289 +name: MHC class II protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] +comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children. +synonym: "major histocompatibility complex class II binding" EXACT [] +synonym: "major histocompatibility complex class II ligand" NARROW [] +is_a: GO:0042287 ! MHC protein binding + +[Term] +id: GO:0042290 +name: obsolete URM1 hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. +synonym: "URM1 hydrolase activity" EXACT [] +is_obsolete: true +consider: GO:0019783 + +[Term] +id: GO:0042291 +name: obsolete Hub1 hydrolase activity +namespace: molecular_function +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:mah] +comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. +synonym: "Hub1 hydrolase activity" EXACT [] +is_obsolete: true +consider: GO:0019783 + +[Term] +id: GO:0042292 +name: URM1 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0042293 +name: Hub1 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity + +[Term] +id: GO:0042294 +name: URM1 transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages." [GOC:mah, PMID:12826404] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity + +[Term] +id: GO:0042296 +name: ISG15 transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages." [GOC:mah, PMID:12826404] +synonym: "ISG15 conjugating enzyme activity" NARROW [] +xref: Reactome:R-HSA-5653754 "UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA" +is_a: GO:0019787 ! ubiquitin-like protein transferase activity + +[Term] +id: GO:0042297 +name: vocal learning +namespace: biological_process +def: "A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others." [GOC:BHF, GOC:dos, GOC:rl, PMID:16418265, PMID:17035521] +comment: Examples include language learning by human infants and song learning in zebra finches. +xref: Wikipedia:Vocal_learning +is_a: GO:0031223 ! auditory behavior +is_a: GO:0098596 ! imitative learning +is_a: GO:0098598 ! learned vocalization behavior or vocal learning + +[Term] +id: GO:0042299 +name: lupeol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol." [MetaCyc:RXN-111, PMID:9883589] +synonym: "oxidosqualene:lupeol cyclase activity" EXACT [PMID:18033581] +xref: EC:5.4.99 +xref: MetaCyc:RXN-111 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0042300 +name: beta-amyrin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin." [PMID:9746369] +synonym: "oxidosqualene:beta-amyrin cyclase activity" EXACT [PMID:18033581] +xref: EC:5.4.99 +xref: MetaCyc:RXN-7570 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0042301 +name: phosphate ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphate." [GOC:jl] +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0042302 +name: structural constituent of cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a cuticle." [GOC:jl] +subset: goslim_drosophila +is_a: GO:0005198 ! structural molecule activity + +[Term] +id: GO:0042303 +name: molting cycle +namespace: biological_process +def: "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." [GOC:jl, ISBN:0198506732] +subset: goslim_drosophila +subset: goslim_pir +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0042304 +name: regulation of fatty acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils." [GOC:go_curators, GOC:jl] +synonym: "regulation of fatty acid anabolism" EXACT [] +synonym: "regulation of fatty acid biosynthesis" EXACT [] +synonym: "regulation of fatty acid formation" EXACT [] +synonym: "regulation of fatty acid synthesis" EXACT [] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006633 ! fatty acid biosynthetic process +relationship: regulates GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0042305 +name: specification of segmental identity, mandibular segment +namespace: biological_process +def: "The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [ISBN:0878932437] +comment: See also the fly_anatomy.ontology term 'mandibular segment ; FBbt:00000012'. +is_a: GO:0007380 ! specification of segmental identity, head +relationship: part_of GO:0035289 ! posterior head segmentation + +[Term] +id: GO:0042306 +name: regulation of protein import into nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus." [GOC:jl] +synonym: "regulation of protein import into cell nucleus" EXACT [] +synonym: "regulation of protein transport from cytoplasm to nucleus" EXACT [] +synonym: "regulation of protein-nucleus import" EXACT [] +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +is_a: GO:1900180 ! regulation of protein localization to nucleus +is_a: GO:1904589 ! regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006606 ! protein import into nucleus +relationship: regulates GO:0006606 ! protein import into nucleus + +[Term] +id: GO:0042307 +name: positive regulation of protein import into nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus." [GOC:jl] +synonym: "activation of protein import into nucleus" NARROW [] +synonym: "positive regulation of protein import into cell nucleus" EXACT [] +synonym: "positive regulation of protein transport from cytoplasm to nucleus" EXACT [] +synonym: "positive regulation of protein-nucleus import" EXACT [] +synonym: "stimulation of protein import into nucleus" NARROW [] +synonym: "up regulation of protein import into nucleus" EXACT [] +synonym: "up-regulation of protein import into nucleus" EXACT [] +synonym: "upregulation of protein import into nucleus" EXACT [] +is_a: GO:0042306 ! regulation of protein import into nucleus +is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1900182 ! positive regulation of protein localization to nucleus +is_a: GO:1904591 ! positive regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006606 ! protein import into nucleus +relationship: positively_regulates GO:0006606 ! protein import into nucleus + +[Term] +id: GO:0042308 +name: negative regulation of protein import into nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus." [GOC:jl] +synonym: "down regulation of protein import into nucleus" EXACT [] +synonym: "down-regulation of protein import into nucleus" EXACT [] +synonym: "downregulation of protein import into nucleus" EXACT [] +synonym: "inhibition of protein import into nucleus" NARROW [] +synonym: "negative regulation of protein import into cell nucleus" EXACT [] +synonym: "negative regulation of protein transport from cytoplasm to nucleus" EXACT [] +synonym: "negative regulation of protein-nucleus import" EXACT [] +is_a: GO:0042306 ! regulation of protein import into nucleus +is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1900181 ! negative regulation of protein localization to nucleus +is_a: GO:1904590 ! negative regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006606 ! protein import into nucleus +relationship: negatively_regulates GO:0006606 ! protein import into nucleus + +[Term] +id: GO:0042309 +name: homoiothermy +namespace: biological_process +def: "Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment." [ISBN:0192801023] +synonym: "antifreeze activity" RELATED [] +synonym: "ice nucleation activity" RELATED [] +synonym: "ice nucleation inhibitor activity" RELATED [] +is_a: GO:0001659 ! temperature homeostasis + +[Term] +id: GO:0042310 +name: vasoconstriction +namespace: biological_process +def: "A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure." [GOC:pr, ISBN:0192800752] +synonym: "negative regulation of blood vessel size" EXACT [] +xref: Wikipedia:Vasoconstriction +is_a: GO:0097756 ! negative regulation of blood vessel diameter + +[Term] +id: GO:0042311 +name: vasodilation +namespace: biological_process +def: "An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure." [GOC:pr, ISBN:0192800981] +synonym: "positive regulation of blood vessel size" EXACT [] +synonym: "vasodilatation" EXACT [] +xref: Wikipedia:Vasodilation +is_a: GO:0097755 ! positive regulation of blood vessel diameter + +[Term] +id: GO:0042313 +name: protein kinase C deactivation +namespace: biological_process +def: "Any process resulting in the inhibition or termination of the activity of protein kinase C." [GOC:bf] +synonym: "PKC deactivation" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway + +[Term] +id: GO:0042314 +name: bacteriochlorophyll binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants." [ISBN:0192800981] +is_a: GO:0016168 ! chlorophyll binding + +[Term] +id: GO:0042315 +name: obsolete cytosol nonspecific dipeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids." [EC:3.4.13.18] +comment: This term was made obsolete because it represents a gene product. +synonym: "cytosol non-specific dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "cytosol nonspecific dipeptidase activity" EXACT [] +synonym: "diglycinase activity" EXACT [EC:3.4.13.18] +synonym: "Gly-Leu hydrolase activity" EXACT [EC:3.4.13.18] +synonym: "glycyl-glycine dipeptidase activity" NARROW [EC:3.4.13.18] +synonym: "glycyl-L-leucine dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "glycyl-L-leucine hydrolase activity" EXACT [EC:3.4.13.18] +synonym: "glycyl-L-leucine peptidase activity" EXACT [EC:3.4.13.18] +synonym: "glycyl-leucine dipeptidase activity" NARROW [EC:3.4.13.18] +synonym: "glycylleucine dipeptide hydrolase activity" EXACT [EC:3.4.13.18] +synonym: "glycylleucine hydrolase activity" EXACT [EC:3.4.13.18] +synonym: "glycylleucine peptidase activity" EXACT [EC:3.4.13.18] +synonym: "human cytosolic non-specific dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "iminodipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "L-amino-acyl-L-amino-acid hydrolase activity" EXACT [EC:3.4.13.18] +synonym: "L-prolylglycine dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "N(2)-beta-alanylarginine dipeptidase activity" NARROW [EC:3.4.13.18] +synonym: "N2-beta-alanylarginine dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "non-specific dipeptidase activity" EXACT [EC:3.4.13.18] +synonym: "peptidase A activity" BROAD [EC:3.4.13.18] +synonym: "Pro-X dipeptidase activity" NARROW [EC:3.4.13.18] +synonym: "prolinase activity" NARROW [EC:3.4.13.18] +synonym: "prolyl dipeptidase activity" NARROW [EC:3.4.13.18] +synonym: "prolylglycine dipeptidase activity" NARROW [EC:3.4.13.18] +xref: EC:3.4.13.18 +xref: MetaCyc:3.4.13.18-RXN +is_obsolete: true +replaced_by: GO:0016805 + +[Term] +id: GO:0042316 +name: penicillin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus." [GOC:jl, ISBN:0198506732] +synonym: "penicillin metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0042317 +name: penicillin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:jl, ISBN:0198506732] +synonym: "penicillin breakdown" EXACT [] +synonym: "penicillin catabolism" EXACT [] +synonym: "penicillin degradation" EXACT [] +is_a: GO:0030655 ! beta-lactam antibiotic catabolic process +is_a: GO:0042316 ! penicillin metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process + +[Term] +id: GO:0042318 +name: penicillin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:jl, ISBN:0198506732] +synonym: "penicillin anabolism" EXACT [] +synonym: "penicillin biosynthesis" EXACT [] +synonym: "penicillin formation" EXACT [] +synonym: "penicillin synthesis" EXACT [] +is_a: GO:0030654 ! beta-lactam antibiotic biosynthetic process +is_a: GO:0042316 ! penicillin metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0042320 +name: regulation of circadian sleep/wake cycle, REM sleep +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep." [GOC:jl, PMID:11506998] +synonym: "regulation of REM sleep" EXACT [] +is_a: GO:0045187 ! regulation of circadian sleep/wake cycle, sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep +relationship: regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep + +[Term] +id: GO:0042321 +name: negative regulation of circadian sleep/wake cycle, sleep +namespace: biological_process +def: "Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals." [GOC:go_curators, GOC:jl, ISBN:0192800981] +synonym: "down regulation of circadian sleep/wake cycle, sleep" EXACT [] +synonym: "down-regulation of circadian sleep/wake cycle, sleep" EXACT [] +synonym: "downregulation of circadian sleep/wake cycle, sleep" EXACT [] +synonym: "inhibition of circadian sleep/wake cycle, sleep" NARROW [] +synonym: "negative regulation of sleep" EXACT [] +is_a: GO:0042754 ! negative regulation of circadian rhythm +is_a: GO:0045187 ! regulation of circadian sleep/wake cycle, sleep +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050802 ! circadian sleep/wake cycle, sleep +relationship: negatively_regulates GO:0050802 ! circadian sleep/wake cycle, sleep + +[Term] +id: GO:0042322 +name: negative regulation of circadian sleep/wake cycle, REM sleep +namespace: biological_process +def: "Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep." [GOC:go_curators, GOC:jl] +synonym: "down regulation of circadian sleep/wake cycle, REM sleep" EXACT [] +synonym: "down-regulation of circadian sleep/wake cycle, REM sleep" EXACT [] +synonym: "downregulation of circadian sleep/wake cycle, REM sleep" EXACT [] +synonym: "inhibition of circadian sleep/wake cycle, REM sleep" NARROW [] +synonym: "negative regulation of REM sleep" EXACT [] +is_a: GO:0042320 ! regulation of circadian sleep/wake cycle, REM sleep +is_a: GO:0042321 ! negative regulation of circadian sleep/wake cycle, sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep +relationship: negatively_regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep + +[Term] +id: GO:0042323 +name: negative regulation of circadian sleep/wake cycle, non-REM sleep +namespace: biological_process +def: "Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep." [GOC:jl] +synonym: "down regulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +synonym: "down-regulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +synonym: "downregulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +synonym: "inhibition of circadian sleep/wake cycle, non-REM sleep" NARROW [] +synonym: "negative regulation of non-REM sleep" EXACT [] +is_a: GO:0042321 ! negative regulation of circadian sleep/wake cycle, sleep +is_a: GO:0045188 ! regulation of circadian sleep/wake cycle, non-REM sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep +relationship: negatively_regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep + +[Term] +id: GO:0042324 +name: hypocretin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the hypocretin receptor." [GOC:ceb, PMID:11988773] +synonym: "hypocretin receptor ligand" NARROW [] +synonym: "orexin receptor binding" EXACT [] +synonym: "orexin receptor ligand" NARROW [] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0042325 +name: regulation of phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016310 ! phosphorylation +relationship: regulates GO:0016310 ! phosphorylation + +[Term] +id: GO:0042326 +name: negative regulation of phosphorylation +namespace: biological_process +def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] +synonym: "down regulation of phosphorylation" EXACT [] +synonym: "down-regulation of phosphorylation" EXACT [] +synonym: "downregulation of phosphorylation" EXACT [] +synonym: "inhibition of phosphorylation" NARROW [] +is_a: GO:0042325 ! regulation of phosphorylation +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016310 ! phosphorylation +relationship: negatively_regulates GO:0016310 ! phosphorylation + +[Term] +id: GO:0042327 +name: positive regulation of phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl] +synonym: "activation of phosphorylation" NARROW [] +synonym: "stimulation of phosphorylation" NARROW [] +synonym: "up regulation of phosphorylation" EXACT [] +synonym: "up-regulation of phosphorylation" EXACT [] +synonym: "upregulation of phosphorylation" EXACT [] +is_a: GO:0042325 ! regulation of phosphorylation +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016310 ! phosphorylation +relationship: positively_regulates GO:0016310 ! phosphorylation + +[Term] +id: GO:0042328 +name: heparan sulfate N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate." [GOC:ma] +synonym: "heparan sulphate N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "heparin N-acetylglucosaminyltransferase activity" RELATED [] +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0042329 +name: structural constituent of collagen and cuticulin-based cuticle +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans." [GOC:jl, GOC:mtg_sensu] +synonym: "structural constituent of cuticle" BROAD [] +is_a: GO:0042302 ! structural constituent of cuticle + +[Term] +id: GO:0042330 +name: taxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to an external stimulus." [GOC:jl, ISBN:0192801023] +synonym: "directed movement in response to stimulus" EXACT [] +xref: Wikipedia:Taxis +is_a: GO:0040011 ! locomotion +relationship: part_of GO:0009605 ! response to external stimulus + +[Term] +id: GO:0042331 +name: phototaxis +namespace: biological_process +alt_id: GO:0046953 +def: "The directed movement of a motile cell or organism in response to light." [GOC:jl, ISBN:0192800981] +synonym: "phototactic behavior" EXACT [] +synonym: "phototactic behaviour" EXACT [] +synonym: "taxis in response to light" EXACT [] +xref: Wikipedia:Phototaxis +is_a: GO:0009416 ! response to light stimulus +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0042332 +name: gravitaxis +namespace: biological_process +alt_id: GO:0048062 +def: "The directed movement of a motile cell or organism in response to gravity." [GOC:jid, GOC:jl] +synonym: "geotactic behavior" EXACT [] +synonym: "geotactic behaviour" EXACT [] +synonym: "geotaxis" EXACT [] +synonym: "gravitactic behavior" EXACT [] +synonym: "gravitactic behaviour" EXACT [] +synonym: "taxis in response to gravitational stimulus" EXACT [] +synonym: "taxis in response to gravity" EXACT [] +is_a: GO:0009629 ! response to gravity +is_a: GO:0042330 ! taxis + +[Term] +id: GO:0042333 +name: chemotaxis to oxidizable substrate +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose." [GOC:jl, PMID:11029423] +synonym: "taxis in response to oxidizable substrate" EXACT [] +is_a: GO:0006935 ! chemotaxis +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0042334 +name: taxis to electron acceptor +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate." [GOC:jl, PMID:11029423] +synonym: "taxis in response to electron acceptor" EXACT [] +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0042335 +name: cuticle development +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." [ISBN:0192800825] +subset: goslim_drosophila +synonym: "cuticle anabolism" EXACT [] +synonym: "cuticle biosynthesis" EXACT [] +synonym: "cuticle biosynthetic process" EXACT [] +synonym: "cuticle formation" EXACT [] +synonym: "cuticle synthesis" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0042336 +name: obsolete cuticle development involved in protein-based cuticle molting cycle +namespace: biological_process +def: "OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. Examples of this process are found in invertebrate species." [GOC:dph, GOC:mtg_sensu, GOC:tb] +comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term. +synonym: "cuticle anabolism during molting" BROAD [] +synonym: "cuticle biosynthetic process during molting" BROAD [] +synonym: "cuticle development involved in protein-based cuticle molting cycle" EXACT [] +synonym: "cuticle formation during molting" BROAD [] +synonym: "cuticle synthesis during molting" BROAD [] +is_obsolete: true +consider: GO:0042337 +consider: GO:0042338 + +[Term] +id: GO:0042337 +name: cuticle development involved in chitin-based cuticle molting cycle +namespace: biological_process +def: "The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:jl, GOC:mtg_sensu, GOC:tb] +synonym: "chitin-based cuticle development during molting" RELATED [GOC:dph, GOC:tb] +synonym: "cuticle anabolism during molting" BROAD [] +synonym: "cuticle biosynthetic process during molting" BROAD [] +synonym: "cuticle formation during molting" BROAD [] +synonym: "cuticle synthesis during molting" BROAD [] +is_a: GO:0040003 ! chitin-based cuticle development +intersection_of: GO:0042335 ! cuticle development +intersection_of: part_of GO:0007591 ! molting cycle, chitin-based cuticle +relationship: part_of GO:0007591 ! molting cycle, chitin-based cuticle + +[Term] +id: GO:0042338 +name: cuticle development involved in collagen and cuticulin-based cuticle molting cycle +namespace: biological_process +def: "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans." [GOC:mtg_sensu] +synonym: "collagen and cuticulin-based cuticle development during molting" RELATED [GOC:dph, GOC:tb] +synonym: "cuticle anabolism during molting" BROAD [] +synonym: "cuticle biosynthetic process during molting" BROAD [] +synonym: "cuticle formation during molting" BROAD [] +synonym: "cuticle synthesis during molting" BROAD [] +is_a: GO:0040002 ! collagen and cuticulin-based cuticle development +intersection_of: GO:0042335 ! cuticle development +intersection_of: part_of GO:0018996 ! molting cycle, collagen and cuticulin-based cuticle +relationship: part_of GO:0018996 ! molting cycle, collagen and cuticulin-based cuticle + +[Term] +id: GO:0042339 +name: keratan sulfate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues." [GOC:go_curators] +synonym: "keratan sulfate metabolism" EXACT [] +synonym: "keratan sulphate metabolic process" EXACT [] +synonym: "keratan sulphate metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:1903510 ! mucopolysaccharide metabolic process + +[Term] +id: GO:0042340 +name: keratan sulfate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues." [GOC:go_curators] +synonym: "keratan sulfate breakdown" EXACT [] +synonym: "keratan sulfate catabolism" EXACT [] +synonym: "keratan sulfate degradation" EXACT [] +synonym: "keratan sulphate catabolic process" EXACT [] +synonym: "keratan sulphate catabolism" EXACT [] +is_a: GO:0006027 ! glycosaminoglycan catabolic process +is_a: GO:0042339 ! keratan sulfate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0042341 +name: cyanogenic glycoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits." [ISBN:0198506732] +synonym: "cyanogenic glycoside metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0050898 ! nitrile metabolic process + +[Term] +id: GO:0042342 +name: cyanogenic glycoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits." [ISBN:0198506732] +synonym: "cyanogenic glycoside breakdown" EXACT [] +synonym: "cyanogenic glycoside catabolism" EXACT [] +synonym: "cyanogenic glycoside degradation" EXACT [] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0042341 ! cyanogenic glycoside metabolic process +is_a: GO:0050899 ! nitrile catabolic process + +[Term] +id: GO:0042343 +name: indole glucosinolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan." [GOC:curators] +synonym: "indole glucosinolate metabolism" EXACT [] +is_a: GO:0019760 ! glucosinolate metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process + +[Term] +id: GO:0042344 +name: indole glucosinolate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan." [PMID:29122987] +synonym: "indole glucosinolate breakdown" EXACT [] +synonym: "indole glucosinolate catabolism" EXACT [] +synonym: "indole glucosinolate degradation" EXACT [] +is_a: GO:0019762 ! glucosinolate catabolic process +is_a: GO:0042343 ! indole glucosinolate metabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process + +[Term] +id: GO:0042349 +name: guiding stereospecific synthesis activity +namespace: molecular_function +def: "The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis." [GOC:ma] +synonym: "dirigent protein" NARROW [] +is_a: GO:0030234 ! enzyme regulator activity + +[Term] +id: GO:0042350 +name: GDP-L-fucose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate." [GOC:jl] +synonym: "GDP-L-fucose anabolism" EXACT [] +synonym: "GDP-L-fucose biosynthesis" EXACT [] +synonym: "GDP-L-fucose formation" EXACT [] +synonym: "GDP-L-fucose synthesis" EXACT [] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046368 ! GDP-L-fucose metabolic process + +[Term] +id: GO:0042351 +name: 'de novo' GDP-L-fucose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271)." [EC:1.1.1.271, PMID:11030750] +synonym: "'de novo' GDP-L-fucose anabolism" EXACT [] +synonym: "'de novo' GDP-L-fucose biosynthesis" EXACT [] +synonym: "'de novo' GDP-L-fucose formation" EXACT [] +synonym: "'de novo' GDP-L-fucose synthesis" EXACT [] +synonym: "GDP-L-fucose biosynthesis, de novo pathway" EXACT [] +synonym: "GDP-L-fucose biosynthetic process, de novo pathway" EXACT [] +xref: MetaCyc:PWY-66 +is_a: GO:0042350 ! GDP-L-fucose biosynthetic process + +[Term] +id: GO:0042352 +name: GDP-L-fucose salvage +namespace: biological_process +def: "The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30)." [GOC:ma] +synonym: "GDP-L-fucose biosynthesis, salvage pathway" EXACT [] +synonym: "GDP-L-fucose biosynthetic process, salvage pathway" EXACT [] +xref: MetaCyc:PWY-6 +is_a: GO:0042350 ! GDP-L-fucose biosynthetic process +is_a: GO:0043173 ! nucleotide salvage + +[Term] +id: GO:0042353 +name: fucose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose)." [GOC:jl] +synonym: "fucose anabolism" EXACT [] +synonym: "fucose biosynthesis" EXACT [] +synonym: "fucose formation" EXACT [] +synonym: "fucose synthesis" EXACT [] +is_a: GO:0006004 ! fucose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0042354 +name: L-fucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants." [GOC:jl, ISBN:0198506732] +synonym: "L-fucose metabolism" EXACT [] +is_a: GO:0006004 ! fucose metabolic process + +[Term] +id: GO:0042355 +name: L-fucose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose)." [GOC:jl] +synonym: "L-fucose breakdown" EXACT [] +synonym: "L-fucose catabolism" EXACT [] +synonym: "L-fucose degradation" EXACT [] +is_a: GO:0019317 ! fucose catabolic process +is_a: GO:0042354 ! L-fucose metabolic process + +[Term] +id: GO:0042356 +name: GDP-4-dehydro-D-rhamnose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed." [BRENDA:1.1.1.187, EC:1.1.1.187] +synonym: "GDP-4-keto-6-deoxy-D-mannose reductase activity" EXACT [EC:1.1.1.187] +synonym: "GDP-4-keto-D-rhamnose reductase activity" EXACT [EC:1.1.1.187] +synonym: "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity" EXACT [EC:1.1.1.187] +synonym: "guanosine diphosphate-4-keto-D-rhamnose reductase activity" EXACT [EC:1.1.1.187] +xref: EC:1.1.1.187 +xref: MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0042357 +name: thiamine diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle." [GOC:jl, ISBN:0198506732] +synonym: "thiamin diphosphate metabolic process" EXACT [] +synonym: "thiamin diphosphate metabolism" EXACT [] +synonym: "thiamin pyrophosphate metabolic process" EXACT [] +synonym: "thiamin pyrophosphate metabolism" EXACT [] +synonym: "thiamine diphosphate metabolism" EXACT [] +synonym: "thiamine pyrophosphate metabolic process" EXACT [] +synonym: "thiamine pyrophosphate metabolism" EXACT [] +synonym: "TPP metabolic process" EXACT [] +synonym: "TPP metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0042358 +name: thiamine diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle." [GOC:jl, ISBN:0198506732] +synonym: "thiamin diphosphate breakdown" EXACT [] +synonym: "thiamin diphosphate catabolic process" EXACT [] +synonym: "thiamin diphosphate catabolism" EXACT [] +synonym: "thiamin diphosphate degradation" EXACT [] +synonym: "thiamin pyrophosphate catabolic process" EXACT [] +synonym: "thiamin pyrophosphate catabolism" EXACT [] +synonym: "thiamine diphosphate catabolism" EXACT [] +synonym: "thiamine pyrophosphate catabolic process" EXACT [] +synonym: "thiamine pyrophosphate catabolism" EXACT [] +synonym: "TPP catabolic process" EXACT [] +synonym: "TPP catabolism" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042357 ! thiamine diphosphate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0042359 +name: vitamin D metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [GOC:mah, ISBN:0471331309] +synonym: "calciferol metabolic process" NARROW [] +synonym: "calciferol metabolism" NARROW [] +synonym: "cholecalciferol metabolic process" NARROW [] +synonym: "cholecalciferol metabolism" NARROW [] +synonym: "ergocalciferol metabolic process" NARROW [] +synonym: "ergocalciferol metabolism" NARROW [] +synonym: "vitamin D metabolism" EXACT [] +is_a: GO:0006775 ! fat-soluble vitamin metabolic process +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042360 +name: vitamin E metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant." [GOC:jl, ISBN:0198506732] +synonym: "alpha-tocopherol metabolic process" NARROW [] +synonym: "alpha-tocopherol metabolism" NARROW [] +synonym: "tocopherol metabolic process" EXACT [] +synonym: "tocopherol metabolism" EXACT [] +synonym: "vitamin E metabolism" EXACT [] +is_a: GO:0006775 ! fat-soluble vitamin metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042361 +name: menaquinone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "menaquinone breakdown" EXACT [] +synonym: "menaquinone catabolism" EXACT [] +synonym: "menaquinone degradation" EXACT [] +synonym: "menatetrenone catabolic process" EXACT [] +synonym: "menatetrenone catabolism" EXACT [] +synonym: "multiprenylmenaquinone catabolic process" EXACT [] +synonym: "multiprenylmenaquinone catabolism" EXACT [] +synonym: "vitamin K2 catabolic process" EXACT [] +synonym: "vitamin K2 catabolism" EXACT [] +is_a: GO:0009233 ! menaquinone metabolic process +is_a: GO:1901662 ! quinone catabolic process + +[Term] +id: GO:0042362 +name: fat-soluble vitamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water." [GOC:jl, ISBN:0198506732] +synonym: "fat-soluble vitamin anabolism" EXACT [] +synonym: "fat-soluble vitamin biosynthesis" EXACT [] +synonym: "fat-soluble vitamin formation" EXACT [] +synonym: "fat-soluble vitamin synthesis" EXACT [] +is_a: GO:0006775 ! fat-soluble vitamin metabolic process +is_a: GO:0009110 ! vitamin biosynthetic process + +[Term] +id: GO:0042363 +name: fat-soluble vitamin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water." [GOC:jl, ISBN:0198506732] +synonym: "fat-soluble vitamin breakdown" EXACT [] +synonym: "fat-soluble vitamin catabolism" EXACT [] +synonym: "fat-soluble vitamin degradation" EXACT [] +is_a: GO:0006775 ! fat-soluble vitamin metabolic process +is_a: GO:0009111 ! vitamin catabolic process + +[Term] +id: GO:0042364 +name: water-soluble vitamin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water." [GOC:jl] +synonym: "water-soluble vitamin anabolism" EXACT [] +synonym: "water-soluble vitamin biosynthesis" EXACT [] +synonym: "water-soluble vitamin formation" EXACT [] +synonym: "water-soluble vitamin synthesis" EXACT [] +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0009110 ! vitamin biosynthetic process + +[Term] +id: GO:0042365 +name: water-soluble vitamin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "water-soluble vitamin breakdown" EXACT [] +synonym: "water-soluble vitamin catabolism" EXACT [] +synonym: "water-soluble vitamin degradation" EXACT [] +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0009111 ! vitamin catabolic process + +[Term] +id: GO:0042366 +name: cobalamin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:go_curators] +synonym: "cobalamin breakdown" EXACT [] +synonym: "cobalamin catabolism" EXACT [] +synonym: "cobalamin degradation" EXACT [] +synonym: "vitamin B12 catabolic process" EXACT [] +synonym: "vitamin B12 catabolism" EXACT [] +is_a: GO:0009235 ! cobalamin metabolic process +is_a: GO:0033015 ! tetrapyrrole catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0042367 +name: biotin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid." [ISBN:0198506732] +synonym: "biotin breakdown" EXACT [] +synonym: "biotin catabolism" EXACT [] +synonym: "biotin degradation" EXACT [] +synonym: "vitamin B7 catabolic process" EXACT [] +synonym: "vitamin B7 catabolism" EXACT [] +synonym: "vitamin H catabolic process" EXACT [] +synonym: "vitamin H catabolism" EXACT [] +is_a: GO:0006768 ! biotin metabolic process +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043605 ! cellular amide catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042368 +name: vitamin D biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [GOC:mah, ISBN:0471331309] +synonym: "calciferol biosynthesis" NARROW [] +synonym: "calciferol biosynthetic process" NARROW [] +synonym: "cholecalciferol biosynthesis" NARROW [] +synonym: "cholecalciferol biosynthetic process" NARROW [] +synonym: "ergocalciferol biosynthesis" NARROW [] +synonym: "ergocalciferol biosynthetic process" NARROW [] +synonym: "vitamin D anabolism" EXACT [] +synonym: "vitamin D biosynthesis" EXACT [] +synonym: "vitamin D formation" EXACT [] +synonym: "vitamin D synthesis" EXACT [] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0042359 ! vitamin D metabolic process +is_a: GO:0042362 ! fat-soluble vitamin biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0042369 +name: vitamin D catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [GOC:mah, ISBN:0471331309] +synonym: "calciferol catabolic process" NARROW [] +synonym: "calciferol catabolism" NARROW [] +synonym: "cholecalciferol biosynthesis" NARROW [] +synonym: "cholecalciferol biosynthetic process" NARROW [] +synonym: "ergocalciferol biosynthesis" NARROW [] +synonym: "ergocalciferol biosynthetic process" NARROW [] +synonym: "vitamin D breakdown" EXACT [] +synonym: "vitamin D catabolism" EXACT [] +synonym: "vitamin D degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0042359 ! vitamin D metabolic process +is_a: GO:0042363 ! fat-soluble vitamin catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0042370 +name: thiamine diphosphate dephosphorylation +namespace: biological_process +def: "The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle." [GOC:jl, ISBN:0198506732] +synonym: "thiamin diphosphate dephosphorylation" EXACT [] +synonym: "TPP dephosphorylation" EXACT [] +is_a: GO:0042357 ! thiamine diphosphate metabolic process + +[Term] +id: GO:0042371 +name: vitamin K biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "naphthoquinone metabolic process" BROAD [] +synonym: "naphthoquinone metabolism" BROAD [] +synonym: "vitamin K anabolism" EXACT [] +synonym: "vitamin K biosynthesis" EXACT [] +synonym: "vitamin K formation" EXACT [] +synonym: "vitamin K synthesis" EXACT [] +is_a: GO:0042362 ! fat-soluble vitamin biosynthetic process +is_a: GO:0042373 ! vitamin K metabolic process + +[Term] +id: GO:0042372 +name: phylloquinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "phylloquinone anabolism" EXACT [] +synonym: "phylloquinone biosynthesis" EXACT [] +synonym: "phylloquinone formation" EXACT [] +synonym: "phylloquinone synthesis" EXACT [] +synonym: "phytomenadione biosynthesis" EXACT [] +synonym: "phytomenadione biosynthetic process" EXACT [] +synonym: "phytonadione biosynthesis" EXACT [] +synonym: "phytonadione biosynthetic process" EXACT [] +synonym: "phytylmenaquinone biosynthesis" EXACT [] +synonym: "phytylmenaquinone biosynthetic process" EXACT [] +synonym: "vitamin K1 biosynthesis" EXACT [] +synonym: "vitamin K1 biosynthetic process" EXACT [] +xref: MetaCyc:PWY-5027 +is_a: GO:0009110 ! vitamin biosynthetic process +is_a: GO:0042374 ! phylloquinone metabolic process +is_a: GO:1901663 ! quinone biosynthetic process + +[Term] +id: GO:0042373 +name: vitamin K metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "naphthoquinone metabolic process" BROAD [] +synonym: "naphthoquinone metabolism" BROAD [] +synonym: "vitamin K metabolism" EXACT [] +is_a: GO:0006775 ! fat-soluble vitamin metabolic process + +[Term] +id: GO:0042374 +name: phylloquinone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "phylloquinone metabolism" EXACT [] +synonym: "phytomenadione metabolic process" EXACT [] +synonym: "phytomenadione metabolism" EXACT [] +synonym: "phytonadione metabolic process" EXACT [] +synonym: "phytonadione metabolism" EXACT [] +synonym: "phytylmenaquinone metabolic process" EXACT [] +synonym: "phytylmenaquinone metabolism" EXACT [] +synonym: "vitamin K1 metabolic process" EXACT [] +synonym: "vitamin K1 metabolism" EXACT [] +is_a: GO:0006766 ! vitamin metabolic process +is_a: GO:1901661 ! quinone metabolic process + +[Term] +id: GO:0042376 +name: phylloquinone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "phylloquinone breakdown" EXACT [] +synonym: "phylloquinone catabolism" EXACT [] +synonym: "phylloquinone degradation" EXACT [] +synonym: "phytomenadione catabolic process" EXACT [] +synonym: "phytomenadione catabolism" EXACT [] +synonym: "phytonadione catabolic process" EXACT [] +synonym: "phytonadione catabolism" EXACT [] +synonym: "phytylmenaquinone catabolic process" EXACT [] +synonym: "phytylmenaquinone catabolism" EXACT [] +synonym: "vitamin K1 catabolic process" EXACT [] +synonym: "vitamin K1 catabolism" EXACT [] +is_a: GO:0009111 ! vitamin catabolic process +is_a: GO:0042374 ! phylloquinone metabolic process +is_a: GO:1901662 ! quinone catabolic process + +[Term] +id: GO:0042377 +name: vitamin K catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals." [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k] +synonym: "naphthoquinone catabolic process" EXACT [] +synonym: "naphthoquinone catabolism" EXACT [] +synonym: "vitamin K breakdown" EXACT [] +synonym: "vitamin K catabolism" EXACT [] +synonym: "vitamin K degradation" EXACT [] +is_a: GO:0042363 ! fat-soluble vitamin catabolic process +is_a: GO:0042373 ! vitamin K metabolic process + +[Term] +id: GO:0042379 +name: chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any chemokine receptor." [GOC:ai] +synonym: "chemokine receptor ligand" NARROW [] +is_a: GO:0001664 ! G protein-coupled receptor binding +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0042380 +name: hydroxymethylbutenyl pyrophosphate reductase activity +namespace: molecular_function +def: "Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate." [GOC:js, PMID:11818558] +synonym: "(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0042381 +name: hemolymph coagulation +namespace: biological_process +def: "Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response." [GOC:jl, ISBN:0198506732, PMID:10561606, PMID:11915949] +synonym: "hemolymph clotting" EXACT [] +is_a: GO:0006959 ! humoral immune response +is_a: GO:0007599 ! hemostasis +is_a: GO:0045087 ! innate immune response +is_a: GO:0050817 ! coagulation +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0042382 +name: paraspeckles +namespace: cellular_component +def: "Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei." [GOC:jl, PMID:11790299] +xref: Wikipedia:Paraspeckle +is_a: GO:0016604 ! nuclear body + +[Term] +id: GO:0042383 +name: sarcolemma +namespace: cellular_component +def: "The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers." [ISBN:0198506732] +xref: Wikipedia:Sarcolemma +is_a: GO:0005886 ! plasma membrane + +[Term] +id: GO:0042385 +name: myosin III complex +namespace: cellular_component +def: "A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain." [GOC:jl, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0042386 +name: hemocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [CL:0000387, GOC:jl, GOC:mtg_sensu, PMID:9550723] +synonym: "arthropod blood cell differentiation" EXACT [] +is_a: GO:0002376 ! immune system process +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0042387 +name: plasmatocyte differentiation +namespace: biological_process +def: "The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response." [PMID:11921077, PMID:8174791] +is_a: GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0042388 +name: gibberellic acid mediated signaling pathway, G-alpha-dependent +namespace: biological_process +def: "A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors." [GOC:pj, PMID:11027362] +synonym: "gibberellic acid mediated signalling, G-alpha-dependent" EXACT [] +is_a: GO:0009740 ! gibberellic acid mediated signaling pathway + +[Term] +id: GO:0042389 +name: omega-3 fatty acid desaturase activity +namespace: molecular_function +def: "Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain." [GOC:jl, PMID:9037020] +xref: EC:1.14.99 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0042390 +name: gibberellic acid mediated signaling pathway, G-alpha-independent +namespace: biological_process +def: "A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors." [GOC:pj, PMID:11027362] +synonym: "gibberellic acid mediated signalling, G-alpha-independent" EXACT [] +is_a: GO:0009740 ! gibberellic acid mediated signaling pathway + +[Term] +id: GO:0042391 +name: regulation of membrane potential +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0042392 +name: sphingosine-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate." [GOC:jl, PMID:11331102] +synonym: "sphingosine-1-phosphate phosphohydrolase activity" EXACT [] +synonym: "SPP phosphatase activity" EXACT [] +synonym: "SPPase activity" EXACT [] +xref: MetaCyc:RXN3DJ-25 +xref: Reactome:R-HSA-428690 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]" +xref: Reactome:R-HSA-428696 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]" +xref: Reactome:R-HSA-428701 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]" +is_a: GO:0042577 ! lipid phosphatase activity + +[Term] +id: GO:0042393 +name: histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity." [GOC:jl] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "histone-specific chaperone activity" RELATED [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0042394 +name: obsolete ecdysis, protein-based cuticle +namespace: biological_process +def: "OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates." [GOC:jl, GOC:mtg_sensu] +comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term. +synonym: "ecdysis, protein-based cuticle" EXACT [] +is_obsolete: true +consider: GO:0018990 +consider: GO:0042395 + +[Term] +id: GO:0042395 +name: ecdysis, collagen and cuticulin-based cuticle +namespace: biological_process +def: "The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates." [GOC:jl, GOC:mtg_sensu] +is_a: GO:0022404 ! molting cycle process +relationship: part_of GO:0018996 ! molting cycle, collagen and cuticulin-based cuticle + +[Term] +id: GO:0042396 +name: phosphagen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction." [GOC:jl, ISBN:0198506732] +synonym: "phosphagen anabolism" EXACT [] +synonym: "phosphagen biosynthesis" EXACT [] +synonym: "phosphagen formation" EXACT [] +synonym: "phosphagen synthesis" EXACT [] +is_a: GO:0006599 ! phosphagen metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0042397 +name: phosphagen catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction." [GOC:jl, ISBN:0198506732] +synonym: "phosphagen breakdown" EXACT [] +synonym: "phosphagen catabolism" EXACT [] +synonym: "phosphagen degradation" EXACT [] +is_a: GO:0006599 ! phosphagen metabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046434 ! organophosphate catabolic process + +[Term] +id: GO:0042398 +name: cellular modified amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents." [GOC:ai] +synonym: "amino acid derivative biosynthetic process" EXACT [] +synonym: "cellular amino acid derivative anabolism" EXACT [] +synonym: "cellular amino acid derivative biosynthesis" EXACT [] +synonym: "cellular amino acid derivative biosynthetic process" EXACT [] +synonym: "cellular amino acid derivative formation" EXACT [] +synonym: "cellular amino acid derivative synthesis" EXACT [] +synonym: "cellular modified amino acid anabolism" EXACT [GOC:mah] +synonym: "cellular modified amino acid biosynthesis" EXACT [GOC:mah] +synonym: "cellular modified amino acid formation" EXACT [GOC:mah] +synonym: "cellular modified amino acid synthesis" EXACT [GOC:mah] +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042399 +name: ectoine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria." [GOC:jl, PMID:11823218] +synonym: "ectoine metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0042400 +name: ectoine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria." [GOC:jl, PMID:11823218] +synonym: "ectoine breakdown" EXACT [] +synonym: "ectoine catabolism" EXACT [] +synonym: "ectoine degradation" EXACT [] +is_a: GO:0042399 ! ectoine metabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042401 +name: cellular biogenic amine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] +synonym: "biogenic amine anabolism" EXACT [] +synonym: "biogenic amine biosynthesis" EXACT [] +synonym: "biogenic amine formation" EXACT [] +synonym: "biogenic amine synthesis" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:0009309 ! amine biosynthetic process + +[Term] +id: GO:0042402 +name: cellular biogenic amine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732] +synonym: "biogenic amine breakdown" EXACT [] +synonym: "biogenic amine catabolism" EXACT [] +synonym: "biogenic amine degradation" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:0009310 ! amine catabolic process + +[Term] +id: GO:0042403 +name: thyroid hormone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine." [GOC:jl, ISBN:0198506732] +synonym: "thyroid hormone metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0042404 +name: thyroid hormone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine." [GOC:jl, ISBN:0198506732] +synonym: "thyroid hormone breakdown" EXACT [] +synonym: "thyroid hormone catabolism" EXACT [] +synonym: "thyroid hormone degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0042403 ! thyroid hormone metabolic process +is_a: GO:0042447 ! hormone catabolic process + +[Term] +id: GO:0042405 +name: nuclear inclusion body +namespace: cellular_component +def: "An intranuclear focus at which aggregated proteins have been sequestered." [GOC:jl] +is_a: GO:0016234 ! inclusion body +intersection_of: GO:0016234 ! inclusion body +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0042406 +name: extrinsic component of endoplasmic reticulum membrane +namespace: cellular_component +def: "The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:curators, GOC:dos] +synonym: "extrinsic to endoplasmic reticulum membrane" NARROW [] +synonym: "extrinsic to ER membrane" EXACT [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0005789 ! endoplasmic reticulum membrane +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0042407 +name: cristae formation +namespace: biological_process +def: "The assembly of cristae, the inwards folds of the inner mitochondrial membrane." [GOC:jl, ISBN:0198506732] +is_a: GO:0007007 ! inner mitochondrial membrane organization + +[Term] +id: GO:0042408 +name: obsolete myrcene/(E)-beta-ocimene synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes." [GOC:cr, PMID:10700382] +comment: This term was made obsolete because it represents two activities. +synonym: "myrcene/(E)-beta-ocimene synthase activity" EXACT [] +synonym: "myrcene/ocimene synthase activity" EXACT [] +xref: EC:4.6 +is_obsolete: true + +[Term] +id: GO:0042409 +name: caffeoyl-CoA O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA." [EC:2.1.1.104] +synonym: "caffeoyl coenzyme A methyltransferase activity" EXACT [] +synonym: "caffeoyl-CoA 3-O-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity" EXACT [EC:2.1.1.104] +synonym: "trans-caffeoyl-CoA 3-O-methyltransferase activity" EXACT [EC:2.1.1.104] +xref: EC:2.1.1.104 +xref: MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN +xref: RHEA:16925 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0042410 +name: 6-carboxyhexanoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA." [EC:6.2.1.14, RHEA:14781] +synonym: "6-carboxyhexanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.14] +synonym: "6-carboxyhexanoyl-CoA synthetase activity" EXACT [EC:6.2.1.14] +synonym: "pimeloyl-CoA synthetase activity" EXACT [EC:6.2.1.14] +synonym: "pimelyl-CoA synthetase activity" EXACT [EC:6.2.1.14] +xref: EC:6.2.1.14 +xref: KEGG_REACTION:R03209 +xref: MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN +xref: RHEA:14781 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0042412 +name: taurine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats." [GOC:jl, ISBN:0198600461] +synonym: "taurine anabolism" EXACT [] +synonym: "taurine biosynthesis" EXACT [] +synonym: "taurine formation" EXACT [] +synonym: "taurine synthesis" EXACT [] +is_a: GO:0019530 ! taurine metabolic process +is_a: GO:0046305 ! alkanesulfonate biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042413 +name: carnitine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:jl, ISBN:0198506732] +synonym: "carnitine breakdown" EXACT [] +synonym: "carnitine catabolism" EXACT [] +synonym: "carnitine degradation" EXACT [] +synonym: "vitamin Bt catabolic process" EXACT [] +synonym: "vitamin Bt catabolism" EXACT [] +is_a: GO:0006579 ! amino-acid betaine catabolic process +is_a: GO:0009437 ! carnitine metabolic process + +[Term] +id: GO:0042414 +name: epinephrine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:jl, ISBN:0192801023, ISBN:0198506732] +synonym: "adrenaline metabolic process" EXACT [] +synonym: "adrenaline metabolism" EXACT [] +synonym: "epinephrine metabolism" EXACT [] +is_a: GO:0006584 ! catecholamine metabolic process + +[Term] +id: GO:0042415 +name: norepinephrine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] +synonym: "levarterenol metabolic process" EXACT [] +synonym: "levarterenol metabolism" EXACT [] +synonym: "noradrenaline metabolic process" EXACT [] +synonym: "noradrenaline metabolism" EXACT [] +synonym: "norepinephrine metabolism" EXACT [] +is_a: GO:0006584 ! catecholamine metabolic process + +[Term] +id: GO:0042416 +name: dopamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:jl, ISBN:0198506732] +synonym: "dopamine anabolism" EXACT [] +synonym: "dopamine biosynthesis" EXACT [] +synonym: "dopamine formation" EXACT [] +synonym: "dopamine synthesis" EXACT [] +is_a: GO:0042417 ! dopamine metabolic process +is_a: GO:0042423 ! catecholamine biosynthetic process + +[Term] +id: GO:0042417 +name: dopamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:jl, ISBN:0198506732] +synonym: "dopamine metabolism" EXACT [] +is_a: GO:0006584 ! catecholamine metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0042418 +name: epinephrine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:jl, ISBN:0192801023, ISBN:0198506732] +synonym: "adrenaline biosynthesis" EXACT [] +synonym: "adrenaline biosynthetic process" EXACT [] +synonym: "epinephrine anabolism" EXACT [] +synonym: "epinephrine biosynthesis" EXACT [] +synonym: "epinephrine formation" EXACT [] +synonym: "epinephrine synthesis" EXACT [] +is_a: GO:0042414 ! epinephrine metabolic process +is_a: GO:0042423 ! catecholamine biosynthetic process + +[Term] +id: GO:0042419 +name: epinephrine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:jl, ISBN:0192801023, ISBN:0198506732] +synonym: "adrenaline catabolic process" EXACT [] +synonym: "adrenaline catabolism" EXACT [] +synonym: "epinephrine breakdown" EXACT [] +synonym: "epinephrine catabolism" EXACT [] +synonym: "epinephrine degradation" EXACT [] +is_a: GO:0042414 ! epinephrine metabolic process +is_a: GO:0042424 ! catecholamine catabolic process + +[Term] +id: GO:0042420 +name: dopamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:jl, ISBN:0198506732] +synonym: "dopamine breakdown" EXACT [] +synonym: "dopamine catabolism" EXACT [] +synonym: "dopamine degradation" EXACT [] +is_a: GO:0042417 ! dopamine metabolic process +is_a: GO:0042424 ! catecholamine catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0042421 +name: norepinephrine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] +synonym: "levarterenol biosynthesis" EXACT [] +synonym: "levarterenol biosynthetic process" EXACT [] +synonym: "noradrenaline biosynthesis" EXACT [] +synonym: "noradrenaline biosynthetic process" EXACT [] +synonym: "norepinephrine anabolism" EXACT [] +synonym: "norepinephrine biosynthesis" EXACT [] +synonym: "norepinephrine formation" EXACT [] +synonym: "norepinephrine synthesis" EXACT [] +is_a: GO:0042415 ! norepinephrine metabolic process +is_a: GO:0042423 ! catecholamine biosynthetic process + +[Term] +id: GO:0042422 +name: norepinephrine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] +synonym: "levarterenol catabolic process" EXACT [] +synonym: "levarterenol catabolism" EXACT [] +synonym: "noradrenaline catabolic process" EXACT [] +synonym: "noradrenaline catabolism" EXACT [] +synonym: "norepinephrine breakdown" EXACT [] +synonym: "norepinephrine catabolism" EXACT [] +synonym: "norepinephrine degradation" EXACT [] +xref: Wikipedia:Norepinephrine#Degradation +is_a: GO:0042415 ! norepinephrine metabolic process +is_a: GO:0042424 ! catecholamine catabolic process + +[Term] +id: GO:0042423 +name: catecholamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] +synonym: "catecholamine anabolism" EXACT [] +synonym: "catecholamine biosynthesis" EXACT [] +synonym: "catecholamine formation" EXACT [] +synonym: "catecholamine synthesis" EXACT [] +xref: Wikipedia:Catecholamines +is_a: GO:0006584 ! catecholamine metabolic process +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042424 +name: catecholamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] +synonym: "catecholamine breakdown" EXACT [] +synonym: "catecholamine catabolism" EXACT [] +synonym: "catecholamine degradation" EXACT [] +is_a: GO:0006584 ! catecholamine metabolic process +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042425 +name: choline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:jl, ISBN:0192801023] +synonym: "choline anabolism" EXACT [] +synonym: "choline biosynthesis" EXACT [] +synonym: "choline formation" EXACT [] +synonym: "choline synthesis" EXACT [] +xref: MetaCyc:PWY-4762 +is_a: GO:0019695 ! choline metabolic process +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process + +[Term] +id: GO:0042426 +name: choline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:jl, ISBN:0192801023] +synonym: "choline breakdown" EXACT [] +synonym: "choline catabolism" EXACT [] +synonym: "choline degradation" EXACT [] +is_a: GO:0019695 ! choline metabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process + +[Term] +id: GO:0042427 +name: serotonin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] +synonym: "serotonin anabolism" EXACT [] +synonym: "serotonin biosynthesis" EXACT [] +synonym: "serotonin formation" EXACT [] +synonym: "serotonin synthesis" EXACT [] +xref: Wikipedia:Serotonin +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042428 ! serotonin metabolic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901162 ! primary amino compound biosynthetic process + +[Term] +id: GO:0042428 +name: serotonin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] +synonym: "serotonin metabolism" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:0097164 ! ammonium ion metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0042429 +name: serotonin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] +synonym: "serotonin breakdown" EXACT [] +synonym: "serotonin catabolism" EXACT [] +synonym: "serotonin degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042428 ! serotonin metabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:1901161 ! primary amino compound catabolic process + +[Term] +id: GO:0042430 +name: indole-containing compound metabolic process +namespace: biological_process +alt_id: GO:0042434 +def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah] +synonym: "indole and derivative metabolic process" EXACT [] +synonym: "indole and derivative metabolism" EXACT [] +synonym: "indole derivative metabolic process" NARROW [] +synonym: "indole derivative metabolism" NARROW [] +synonym: "indole-containing compound metabolism" EXACT [] +synonym: "ketole metabolic process" EXACT [] +synonym: "ketole metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0042431 +name: indole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)." [GOC:jl] +synonym: "indole metabolism" EXACT [] +is_a: GO:0042430 ! indole-containing compound metabolic process + +[Term] +id: GO:0042432 +name: indole biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)." [GOC:jl] +synonym: "indole anabolism" EXACT [] +synonym: "indole biosynthesis" EXACT [] +synonym: "indole formation" EXACT [] +synonym: "indole synthesis" EXACT [] +is_a: GO:0042431 ! indole metabolic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process + +[Term] +id: GO:0042433 +name: indole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)." [GOC:jl] +synonym: "indole breakdown" EXACT [] +synonym: "indole catabolism" EXACT [] +synonym: "indole degradation" EXACT [] +is_a: GO:0042431 ! indole metabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process + +[Term] +id: GO:0042435 +name: indole-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] +synonym: "indole derivative biosynthesis" EXACT [] +synonym: "indole derivative biosynthetic process" EXACT [] +synonym: "indole-containing compound anabolism" EXACT [] +synonym: "indole-containing compound biosynthesis" EXACT [] +synonym: "indole-containing compound formation" EXACT [] +synonym: "indole-containing compound synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042436 +name: indole-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] +synonym: "indole derivative catabolic process" EXACT [] +synonym: "indole derivative catabolism" EXACT [] +synonym: "indole-containing compound breakdown" EXACT [] +synonym: "indole-containing compound catabolism" EXACT [] +synonym: "indole-containing compound degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042437 +name: indoleacetic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants." [GOC:jl] +synonym: "IAA catabolic process" EXACT [] +synonym: "indole acetic acid catabolic process" EXACT [] +synonym: "indole acetic acid catabolism" EXACT [] +synonym: "indoleacetic acid breakdown" EXACT [] +synonym: "indoleacetic acid catabolism" EXACT [] +synonym: "indoleacetic acid degradation" EXACT [] +is_a: GO:0009683 ! indoleacetic acid metabolic process +is_a: GO:0009852 ! auxin catabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0042438 +name: melanin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." [GOC:curators] +synonym: "melanin anabolism" EXACT [] +synonym: "melanin biosynthesis" EXACT [] +synonym: "melanin formation" EXACT [] +synonym: "melanin synthesis" EXACT [] +is_a: GO:0006582 ! melanin metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0042439 +name: ethanolamine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it." [GOC:mah] +synonym: "ethanolamine and derivative metabolic process" EXACT [] +synonym: "ethanolamine and derivative metabolism" EXACT [] +synonym: "ethanolamine-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0006576 ! cellular biogenic amine metabolic process + +[Term] +id: GO:0042440 +name: pigment metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin." [GOC:jl, ISBN:0198506732] +subset: goslim_pir +synonym: "pigment metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0042441 +name: eye pigment metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye." [GOC:ai] +synonym: "eye pigment metabolism" EXACT [] +is_a: GO:0043324 ! pigment metabolic process involved in developmental pigmentation +relationship: part_of GO:0048069 ! eye pigmentation + +[Term] +id: GO:0042442 +name: melatonin catabolic process +namespace: biological_process +alt_id: GO:0042449 +def: "The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine)." [GOC:jl] +synonym: "melatonin breakdown" EXACT [] +synonym: "melatonin catabolism" EXACT [] +synonym: "melatonin degradation" EXACT [] +is_a: GO:0030186 ! melatonin metabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0042443 +name: phenylethylamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds." [GOC:jl, ISBN:0395825172] +synonym: "phenylethylamine metabolism" EXACT [] +is_a: GO:0006576 ! cellular biogenic amine metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0042444 +name: phenylethylamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds." [GOC:jl, ISBN:0395825172] +synonym: "phenylethylamine anabolism" EXACT [] +synonym: "phenylethylamine biosynthesis" EXACT [] +synonym: "phenylethylamine formation" EXACT [] +synonym: "phenylethylamine synthesis" EXACT [] +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:0042443 ! phenylethylamine metabolic process +is_a: GO:1901162 ! primary amino compound biosynthetic process + +[Term] +id: GO:0042445 +name: hormone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:jl] +subset: goslim_pir +synonym: "hormone metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process +is_a: GO:0010817 ! regulation of hormone levels +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0042446 +name: hormone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:jl] +synonym: "hormone anabolism" EXACT [] +synonym: "hormone biosynthesis" EXACT [] +synonym: "hormone formation" EXACT [] +synonym: "hormone synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0042447 +name: hormone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:jl] +synonym: "hormone breakdown" EXACT [] +synonym: "hormone catabolism" EXACT [] +synonym: "hormone degradation" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0042445 ! hormone metabolic process + +[Term] +id: GO:0042448 +name: progesterone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants." [GOC:jl, http://www.cogsci.princeton.edu/] +synonym: "progesterone metabolism" EXACT [] +is_a: GO:0008207 ! C21-steroid hormone metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process + +[Term] +id: GO:0042450 +name: arginine biosynthetic process via ornithine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine." [GOC:jl] +synonym: "arginine anabolism via ornithine" EXACT [] +synonym: "arginine formation via ornithine" EXACT [] +synonym: "arginine synthesis via ornithine" EXACT [] +is_a: GO:0006526 ! arginine biosynthetic process +is_a: GO:0006591 ! ornithine metabolic process + +[Term] +id: GO:0042451 +name: purine nucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:go_curators] +synonym: "purine nucleoside anabolism" EXACT [] +synonym: "purine nucleoside biosynthesis" EXACT [] +synonym: "purine nucleoside formation" EXACT [] +synonym: "purine nucleoside synthesis" EXACT [] +is_a: GO:0009163 ! nucleoside biosynthetic process +is_a: GO:0042278 ! purine nucleoside metabolic process +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0042452 +name: deoxyguanosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose." [GOC:jl] +synonym: "deoxyguanosine anabolism" EXACT [] +synonym: "deoxyguanosine biosynthesis" EXACT [] +synonym: "deoxyguanosine formation" EXACT [] +synonym: "deoxyguanosine synthesis" EXACT [] +is_a: GO:0042453 ! deoxyguanosine metabolic process +is_a: GO:0046123 ! purine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0042453 +name: deoxyguanosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose." [GOC:jl] +synonym: "deoxyguanosine metabolism" EXACT [] +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0042454 +name: ribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:jl] +synonym: "ribonucleoside breakdown" EXACT [] +synonym: "ribonucleoside catabolism" EXACT [] +synonym: "ribonucleoside degradation" EXACT [] +is_a: GO:0009119 ! ribonucleoside metabolic process +is_a: GO:0009164 ! nucleoside catabolic process + +[Term] +id: GO:0042455 +name: ribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:jl] +synonym: "ribonucleoside anabolism" EXACT [] +synonym: "ribonucleoside biosynthesis" EXACT [] +synonym: "ribonucleoside formation" EXACT [] +synonym: "ribonucleoside synthesis" EXACT [] +is_a: GO:0009119 ! ribonucleoside metabolic process +is_a: GO:0009163 ! nucleoside biosynthetic process + +[Term] +id: GO:0042457 +name: ethylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator." [GOC:jl, ISBN:0387969845] +synonym: "ethene catabolic process" EXACT [] +synonym: "ethene catabolism" EXACT [] +synonym: "ethylene breakdown" EXACT [] +synonym: "ethylene catabolism" EXACT [] +synonym: "ethylene degradation" EXACT [] +is_a: GO:0009692 ! ethylene metabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0043451 ! alkene catabolic process + +[Term] +id: GO:0042458 +name: nopaline catabolic process to proline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline." [GOC:go_curators] +synonym: "nopaline breakdown to proline" EXACT [] +synonym: "nopaline degradation to proline" EXACT [] +xref: MetaCyc:NOPALINEDEG-PWY +is_a: GO:0006560 ! proline metabolic process +is_a: GO:0019468 ! nopaline catabolic process + +[Term] +id: GO:0042459 +name: octopine catabolic process to proline +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline." [GOC:go_curators] +synonym: "octopine breakdown to proline" EXACT [] +synonym: "octopine degradation to proline" EXACT [] +xref: MetaCyc:OCTOPINEDEG-PWY +is_a: GO:0006560 ! proline metabolic process +is_a: GO:0019469 ! octopine catabolic process + +[Term] +id: GO:0042461 +name: photoreceptor cell development +namespace: biological_process +alt_id: GO:0046531 +def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators] +synonym: "photoreceptor morphogenesis" EXACT [] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0042462 +name: eye photoreceptor cell development +namespace: biological_process +def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981] +is_a: GO:0042461 ! photoreceptor cell development +relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation + +[Term] +id: GO:0042463 +name: ocellus photoreceptor cell development +namespace: biological_process +alt_id: GO:0001749 +def: "Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus." [GOC:jl, ISBN:0192800981, PMID:11542766] +synonym: "non-eye photoreceptor development" BROAD [] +is_a: GO:0042461 ! photoreceptor cell development +relationship: part_of GO:0042705 ! ocellus photoreceptor cell differentiation + +[Term] +id: GO:0042464 +name: dosage compensation by hypoactivation of X chromosome +namespace: biological_process +def: "Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans." [GOC:jl, GOC:mr, PMID:11102361, PMID:20622855, Wikipedia:XY_sex-determination_system] +is_a: GO:0007549 ! dosage compensation +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0042465 +name: kinesis +namespace: biological_process +def: "The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus." [GOC:jl, ISBN:0192801023] +xref: Wikipedia:Kinesis +is_a: GO:0009605 ! response to external stimulus + +[Term] +id: GO:0042466 +name: chemokinesis +namespace: biological_process +def: "A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis)." [GOC:jl, PMID:2073411] +xref: Wikipedia:Chemokinesis +is_a: GO:0042465 ! kinesis + +[Term] +id: GO:0042467 +name: orthokinesis +namespace: biological_process +def: "The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased." [GOC:jl, PMID:8207088] +is_a: GO:0042465 ! kinesis + +[Term] +id: GO:0042468 +name: klinokinesis +namespace: biological_process +def: "The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered." [GOC:jl, PMID:2790068] +is_a: GO:0042465 ! kinesis + +[Term] +id: GO:0042469 +name: versicolorin reductase activity +namespace: molecular_function +def: "Catalysis of the reduction of versicolorin A to sterigmatocystin." [PMID:1339261] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0042470 +name: melanosome +namespace: cellular_component +def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells." [GOC:jl, PMID:11584301] +xref: Wikipedia:Melanosome +is_a: GO:0048770 ! pigment granule +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:6237 + +[Term] +id: GO:0042471 +name: ear morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] +synonym: "hearing organ morphogenesis" EXACT [] +is_a: GO:0048562 ! embryonic organ morphogenesis +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0043583 ! ear development + +[Term] +id: GO:0042472 +name: inner ear morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively." [GOC:jl, ISBN:0192801023] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042471 ! ear morphogenesis +relationship: part_of GO:0048839 ! inner ear development + +[Term] +id: GO:0042473 +name: outer ear morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull." [GOC:jl, ISBN:0192801023] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042471 ! ear morphogenesis + +[Term] +id: GO:0042474 +name: middle ear morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)." [GOC:jl, ISBN:0192801023] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042471 ! ear morphogenesis + +[Term] +id: GO:0042475 +name: odontogenesis of dentin-containing tooth +namespace: biological_process +def: "The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel." [GOC:cjm, GOC:mah, GOC:mtg_sensu, PMID:10333884, PMID:15355794] +comment: Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales. +synonym: "odontogenesis of dentine-containing teeth" EXACT [] +synonym: "odontogenesis of dentine-containing tooth" EXACT [GOC:mah] +synonym: "odontogeny" BROAD [] +synonym: "odontosis" BROAD [] +synonym: "tooth development" BROAD [] +is_a: GO:0042476 ! odontogenesis + +[Term] +id: GO:0042476 +name: odontogenesis +namespace: biological_process +alt_id: GO:0042477 +def: "The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food." [GOC:jl, GOC:mah] +synonym: "odontogenesis of calcareous or chitinous tooth" NARROW [] +synonym: "odontogeny" EXACT [] +synonym: "odontosis" EXACT [] +synonym: "tooth development" RELATED [] +synonym: "tooth morphogenesis" EXACT [] +xref: Wikipedia:Odontogenesis +is_a: GO:0009887 ! animal organ morphogenesis +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0042478 +name: regulation of eye photoreceptor cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] +synonym: "regulation of eye photoreceptor development" EXACT [] +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042462 ! eye photoreceptor cell development +relationship: regulates GO:0042462 ! eye photoreceptor cell development + +[Term] +id: GO:0042479 +name: positive regulation of eye photoreceptor cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] +synonym: "activation of eye photoreceptor cell development" NARROW [] +synonym: "positive regulation of eye photoreceptor development" EXACT [] +synonym: "stimulation of eye photoreceptor cell development" NARROW [] +synonym: "up regulation of eye photoreceptor cell development" EXACT [] +synonym: "up-regulation of eye photoreceptor cell development" EXACT [] +synonym: "upregulation of eye photoreceptor cell development" EXACT [] +is_a: GO:0042478 ! regulation of eye photoreceptor cell development +is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042462 ! eye photoreceptor cell development +relationship: positively_regulates GO:0042462 ! eye photoreceptor cell development + +[Term] +id: GO:0042480 +name: negative regulation of eye photoreceptor cell development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] +synonym: "down regulation of eye photoreceptor cell development" EXACT [] +synonym: "down-regulation of eye photoreceptor cell development" EXACT [] +synonym: "downregulation of eye photoreceptor cell development" EXACT [] +synonym: "inhibition of eye photoreceptor cell development" NARROW [] +synonym: "negative regulation of eye photoreceptor development" EXACT [] +is_a: GO:0042478 ! regulation of eye photoreceptor cell development +is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042462 ! eye photoreceptor cell development +relationship: negatively_regulates GO:0042462 ! eye photoreceptor cell development + +[Term] +id: GO:0042481 +name: regulation of odontogenesis +namespace: biological_process +alt_id: GO:0042484 +def: "Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] +synonym: "regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] +synonym: "regulation of tooth development" EXACT [] +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042476 ! odontogenesis +relationship: regulates GO:0042476 ! odontogenesis + +[Term] +id: GO:0042482 +name: positive regulation of odontogenesis +namespace: biological_process +alt_id: GO:0042485 +def: "Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] +synonym: "activation of odontogenesis" NARROW [] +synonym: "positive regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] +synonym: "positive regulation of tooth development" EXACT [] +synonym: "stimulation of odontogenesis" NARROW [] +synonym: "up regulation of odontogenesis" EXACT [] +synonym: "up-regulation of odontogenesis" EXACT [] +synonym: "upregulation of odontogenesis" EXACT [] +is_a: GO:0042481 ! regulation of odontogenesis +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042476 ! odontogenesis +relationship: positively_regulates GO:0042476 ! odontogenesis + +[Term] +id: GO:0042483 +name: negative regulation of odontogenesis +namespace: biological_process +alt_id: GO:0042486 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] +synonym: "down regulation of odontogenesis" EXACT [] +synonym: "down-regulation of odontogenesis" EXACT [] +synonym: "downregulation of odontogenesis" EXACT [] +synonym: "inhibition of odontogenesis" NARROW [] +synonym: "negative regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] +synonym: "negative regulation of tooth development" EXACT [] +is_a: GO:0042481 ! regulation of odontogenesis +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042476 ! odontogenesis +relationship: negatively_regulates GO:0042476 ! odontogenesis + +[Term] +id: GO:0042487 +name: regulation of odontogenesis of dentin-containing tooth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, GOC:mtg_sensu, PMID:15355794] +synonym: "regulation of odontogenesis of dentine-containing teeth" EXACT [] +synonym: "regulation of odontogenesis of dentine-containing tooth" EXACT [GOC:mah] +is_a: GO:0042481 ! regulation of odontogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042475 ! odontogenesis of dentin-containing tooth +relationship: regulates GO:0042475 ! odontogenesis of dentin-containing tooth + +[Term] +id: GO:0042488 +name: positive regulation of odontogenesis of dentin-containing tooth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, PMID:15355794] +synonym: "activation of odontogenesis" BROAD [] +synonym: "positive regulation of odontogenesis of dentine-containing teeth" EXACT [] +synonym: "positive regulation of odontogenesis of dentine-containing tooth" RELATED [] +synonym: "stimulation of odontogenesis" BROAD [] +synonym: "up regulation of odontogenesis" BROAD [] +synonym: "up-regulation of odontogenesis" BROAD [] +synonym: "upregulation of odontogenesis" BROAD [] +is_a: GO:0042482 ! positive regulation of odontogenesis +is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth +relationship: positively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth + +[Term] +id: GO:0042489 +name: negative regulation of odontogenesis of dentin-containing tooth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx." [GOC:jl, GOC:mtg_sensu, PMID:15355794] +synonym: "down regulation of odontogenesis" BROAD [] +synonym: "down-regulation of odontogenesis" BROAD [] +synonym: "downregulation of odontogenesis" BROAD [] +synonym: "inhibition of odontogenesis" BROAD [] +synonym: "negative regulation of odontogenesis" BROAD [] +synonym: "negative regulation of odontogenesis of dentine-containing teeth" EXACT [] +synonym: "negative regulation of odontogenesis of dentine-containing tooth" RELATED [] +is_a: GO:0042483 ! negative regulation of odontogenesis +is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth +relationship: negatively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth + +[Term] +id: GO:0042490 +name: mechanoreceptor differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system." [CL:0000199, GOC:jl] +is_a: GO:0030182 ! neuron differentiation + +[Term] +id: GO:0042491 +name: inner ear auditory receptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell." [CL:0000201, GOC:jl] +comment: Note that this term refers to the mechanosensory hair cells of the inner ear. +synonym: "auditory hair cell differentiation" EXACT [] +synonym: "auditory receptor cell differentiation" RELATED [] +is_a: GO:0035315 ! hair cell differentiation +is_a: GO:0060113 ! inner ear receptor cell differentiation +is_a: GO:0060563 ! neuroepithelial cell differentiation + +[Term] +id: GO:0042492 +name: gamma-delta T cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex." [CL:0000798, GOC:jl] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "gamma-delta T cell development" RELATED [GOC:add] +synonym: "gamma-delta T lymphocyte differentiation" EXACT [] +synonym: "gamma-delta T-cell differentiation" EXACT [] +synonym: "gamma-delta T-lymphocyte differentiation" EXACT [] +is_a: GO:0030217 ! T cell differentiation +is_a: GO:0046629 ! gamma-delta T cell activation + +[Term] +id: GO:0042493 +name: response to drug +namespace: biological_process +alt_id: GO:0017035 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease." [GOC:jl] +subset: goslim_candida +synonym: "drug resistance" RELATED [] +synonym: "drug susceptibility/resistance" RELATED [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0042494 +name: detection of bacterial lipoprotein +namespace: biological_process +def: "The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs)." [GOC:jl, PMID:12077222] +synonym: "detection of BLP" RELATED [] +synonym: "detection of Lpp" RELATED [] +synonym: "perception of bacterial lipoprotein" RELATED [] +synonym: "perception of BLP" RELATED [] +synonym: "perception of Lpp" RELATED [] +is_a: GO:0032490 ! detection of molecule of bacterial origin +is_a: GO:0032493 ! response to bacterial lipoprotein +relationship: part_of GO:0016045 ! detection of bacterium + +[Term] +id: GO:0042495 +name: detection of triacyl bacterial lipopeptide +namespace: biological_process +def: "The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "detection of triacylated bacterial lipoprotein" EXACT [GOC:add] +synonym: "perception of triacylated bacterial lipopeptide" RELATED [GOC:add] +synonym: "perception of triacylated bacterial lipoprotein" RELATED [] +is_a: GO:0070340 ! detection of bacterial lipopeptide +is_a: GO:0071725 ! response to triacyl bacterial lipopeptide + +[Term] +id: GO:0042496 +name: detection of diacyl bacterial lipopeptide +namespace: biological_process +def: "The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "detection of diacylated bacterial lipoprotein" EXACT [GOC:add] +synonym: "perception of diacylated bacterial lipopeptide" RELATED [GOC:add] +synonym: "perception of diacylated bacterial lipoprotein" RELATED [] +is_a: GO:0070340 ! detection of bacterial lipopeptide +is_a: GO:0071724 ! response to diacyl bacterial lipopeptide + +[Term] +id: GO:0042497 +name: triacyl lipopeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of three acyl groups." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "bacterial triacyl lipopeptide binding" NARROW [GOC:add] +synonym: "bacterial triacyl lipoprotein binding" RELATED [GOC:add] +synonym: "triacylated lipopeptide binding" EXACT [] +is_a: GO:0071723 ! lipopeptide binding + +[Term] +id: GO:0042498 +name: diacyl lipopeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of two acyl groups." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "bacterial diacyl lipopeptide binding" NARROW [GOC:add] +synonym: "bacterial diacyl lipoprotein binding" RELATED [GOC:add] +synonym: "diacylated lipopeptide binding" EXACT [] +is_a: GO:0071723 ! lipopeptide binding + +[Term] +id: GO:0042499 +name: obsolete signal peptide peptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein." [PMID:12077416] +comment: This term was made obsolete because it represents a gene product. +synonym: "signal peptide peptidase activity" EXACT [] +synonym: "SPP" EXACT [] +xref: EC:3.4.23 +is_obsolete: true +replaced_by: GO:0042500 + +[Term] +id: GO:0042500 +name: aspartic endopeptidase activity, intramembrane cleaving +namespace: molecular_function +def: "Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane." [GOC:jl, ISBN:0198506732] +comment: Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases. +xref: EC:3.4.23 +xref: Reactome:R-HSA-8863101 "SPPL2a/b cleaves TNF(1-76)" +is_a: GO:0004190 ! aspartic-type endopeptidase activity + +[Term] +id: GO:0042501 +name: serine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:0033136 +def: "The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] +synonym: "serine phosphorylation of STAT3 protein" NARROW [] +is_a: GO:0018105 ! peptidyl-serine phosphorylation +relationship: part_of GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0042509 +name: regulation of tyrosine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:0042510 +alt_id: GO:0042513 +alt_id: GO:0042516 +alt_id: GO:0042519 +alt_id: GO:0042522 +alt_id: GO:0042525 +alt_id: GO:0042528 +def: "Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] +synonym: "regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +is_a: GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007260 ! tyrosine phosphorylation of STAT protein +relationship: regulates GO:0007260 ! tyrosine phosphorylation of STAT protein + +[Term] +id: GO:0042531 +name: positive regulation of tyrosine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:0042511 +alt_id: GO:0042515 +alt_id: GO:0042517 +alt_id: GO:0042520 +alt_id: GO:0042523 +alt_id: GO:0042526 +alt_id: GO:0042529 +def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] +synonym: "activation of tyrosine phosphorylation of STAT protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "activation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "positive regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of STAT protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "stimulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "up regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "up regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "up-regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "up-regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "upregulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "upregulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +is_a: GO:0042509 ! regulation of tyrosine phosphorylation of STAT protein +is_a: GO:0046427 ! positive regulation of receptor signaling pathway via JAK-STAT +is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein +relationship: positively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein + +[Term] +id: GO:0042532 +name: negative regulation of tyrosine phosphorylation of STAT protein +namespace: biological_process +alt_id: GO:0042512 +alt_id: GO:0042514 +alt_id: GO:0042518 +alt_id: GO:0042521 +alt_id: GO:0042524 +alt_id: GO:0042527 +alt_id: GO:0042530 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] +synonym: "down regulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "down regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "down-regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of STAT protein" EXACT [] +synonym: "downregulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of STAT protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of Stat7 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] +is_a: GO:0042509 ! regulation of tyrosine phosphorylation of STAT protein +is_a: GO:0046426 ! negative regulation of receptor signaling pathway via JAK-STAT +is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein +relationship: negatively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein + +[Term] +id: GO:0042533 +name: tumor necrosis factor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "TNF alpha biosynthesis" EXACT [] +synonym: "TNF alpha biosynthetic process" EXACT [] +synonym: "TNF biosynthesis" EXACT [] +synonym: "TNF biosynthetic process" EXACT [] +synonym: "TNF-alpha biosynthesis" EXACT [] +synonym: "TNF-alpha biosynthetic process" EXACT [] +synonym: "Tumor Necrosis Factor alpha biosynthesis" EXACT [] +synonym: "Tumor Necrosis Factor alpha biosynthetic process" EXACT [] +synonym: "tumor necrosis factor anabolism" EXACT [] +synonym: "tumor necrosis factor biosynthesis" EXACT [] +synonym: "tumor necrosis factor formation" EXACT [] +synonym: "tumor necrosis factor synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032640 ! tumor necrosis factor production + +[Term] +id: GO:0042534 +name: regulation of tumor necrosis factor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "regulation of TNF alpha biosynthesis" EXACT [] +synonym: "regulation of TNF alpha biosynthetic process" EXACT [] +synonym: "regulation of TNF biosynthesis" EXACT [] +synonym: "regulation of TNF biosynthetic process" EXACT [] +synonym: "regulation of TNF-alpha biosynthesis" EXACT [] +synonym: "regulation of TNF-alpha biosynthetic process" EXACT [] +synonym: "regulation of tumor necrosis factor anabolism" EXACT [] +synonym: "regulation of tumor necrosis factor biosynthesis" EXACT [] +synonym: "regulation of tumor necrosis factor formation" EXACT [] +synonym: "regulation of tumor necrosis factor synthesis" EXACT [] +synonym: "regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] +synonym: "regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] +is_a: GO:0032680 ! regulation of tumor necrosis factor production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042533 ! tumor necrosis factor biosynthetic process +relationship: regulates GO:0042533 ! tumor necrosis factor biosynthetic process + +[Term] +id: GO:0042535 +name: positive regulation of tumor necrosis factor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "activation of tumor necrosis factor biosynthetic process" NARROW [] +synonym: "positive regulation of TNF alpha biosynthesis" EXACT [] +synonym: "positive regulation of TNF alpha biosynthetic process" EXACT [] +synonym: "positive regulation of TNF biosynthesis" EXACT [] +synonym: "positive regulation of TNF biosynthetic process" EXACT [] +synonym: "positive regulation of TNF-alpha biosynthesis" EXACT [] +synonym: "positive regulation of TNF-alpha biosynthetic process" EXACT [] +synonym: "positive regulation of tumor necrosis factor anabolism" EXACT [] +synonym: "positive regulation of tumor necrosis factor biosynthesis" EXACT [] +synonym: "positive regulation of tumor necrosis factor formation" EXACT [] +synonym: "positive regulation of tumor necrosis factor synthesis" EXACT [] +synonym: "positive regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] +synonym: "positive regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] +synonym: "stimulation of tumor necrosis factor biosynthetic process" NARROW [] +synonym: "up regulation of tumor necrosis factor biosynthetic process" EXACT [] +synonym: "up-regulation of tumor necrosis factor biosynthetic process" EXACT [] +synonym: "upregulation of tumor necrosis factor biosynthetic process" EXACT [] +is_a: GO:0032760 ! positive regulation of tumor necrosis factor production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0042534 ! regulation of tumor necrosis factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042533 ! tumor necrosis factor biosynthetic process +relationship: positively_regulates GO:0042533 ! tumor necrosis factor biosynthetic process + +[Term] +id: GO:0042536 +name: negative regulation of tumor necrosis factor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] +comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). +synonym: "down regulation of tumor necrosis factor biosynthetic process" EXACT [] +synonym: "down-regulation of tumor necrosis factor biosynthetic process" EXACT [] +synonym: "downregulation of tumor necrosis factor biosynthetic process" EXACT [] +synonym: "inhibition of tumor necrosis factor biosynthetic process" NARROW [] +synonym: "negative regulation of TNF alpha biosynthesis" EXACT [] +synonym: "negative regulation of TNF alpha biosynthetic process" EXACT [] +synonym: "negative regulation of TNF biosynthesis" EXACT [] +synonym: "negative regulation of TNF biosynthetic process" EXACT [] +synonym: "negative regulation of TNF-alpha biosynthesis" EXACT [] +synonym: "negative regulation of TNF-alpha biosynthetic process" EXACT [] +synonym: "negative regulation of tumor necrosis factor anabolism" EXACT [] +synonym: "negative regulation of tumor necrosis factor biosynthesis" EXACT [] +synonym: "negative regulation of tumor necrosis factor formation" EXACT [] +synonym: "negative regulation of tumor necrosis factor synthesis" EXACT [] +synonym: "negative regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] +synonym: "negative regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] +is_a: GO:0032720 ! negative regulation of tumor necrosis factor production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0042534 ! regulation of tumor necrosis factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042533 ! tumor necrosis factor biosynthetic process +relationship: negatively_regulates GO:0042533 ! tumor necrosis factor biosynthetic process + +[Term] +id: GO:0042537 +name: benzene-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives." [GOC:jl] +synonym: "benzene and derivative metabolic process" EXACT [] +synonym: "benzene and derivative metabolism" EXACT [] +synonym: "benzene-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0042538 +name: hyperosmotic salinity response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:jl] +synonym: "response to hyperosmotic salt stress" EXACT [] +synonym: "salt tolerance" RELATED [] +is_a: GO:0006972 ! hyperosmotic response +is_a: GO:0009651 ! response to salt stress + +[Term] +id: GO:0042539 +name: hypotonic salinity response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:jl] +synonym: "response to hypotonic salt stress" EXACT [] +is_a: GO:0006971 ! hypotonic response +is_a: GO:0009651 ! response to salt stress + +[Term] +id: GO:0042540 +name: hemoglobin catabolic process +namespace: biological_process +alt_id: GO:0020029 +def: "The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids." [GOC:jl, GOC:mb] +comment: Note that 'hydrolysis' is actually a reaction rather than a process. The synonym 'hemoglobin hydrolysis' was the text string associated with the secondary ID GO:0020029, which was retained because its definition did describe a process. +synonym: "haemoglobin catabolic process" EXACT [] +synonym: "haemoglobin catabolism" EXACT [] +synonym: "haemoglobin hydrolysis" NARROW [] +synonym: "hemoglobin breakdown" EXACT [] +synonym: "hemoglobin catabolism" EXACT [] +synonym: "hemoglobin degradation" EXACT [] +synonym: "hemoglobin hydrolysis" NARROW [] +is_a: GO:0020027 ! hemoglobin metabolic process +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process + +[Term] +id: GO:0042541 +name: hemoglobin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:jl] +synonym: "haemoglobin biosynthesis" EXACT [] +synonym: "haemoglobin biosynthetic process" EXACT [] +synonym: "hemoglobin anabolism" EXACT [] +synonym: "hemoglobin biosynthesis" EXACT [] +synonym: "hemoglobin formation" EXACT [] +synonym: "hemoglobin synthesis" EXACT [] +is_a: GO:0020027 ! hemoglobin metabolic process +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042542 +name: response to hydrogen peroxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus." [GOC:jl] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic + +[Term] +id: GO:0042543 +name: protein N-linked glycosylation via arginine +namespace: biological_process +def: "The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine." [RESID:AA0327] +synonym: "protein amino acid N-linked glycosylation via arginine" EXACT [GOC:bf] +xref: RESID:AA0327 +is_a: GO:0006487 ! protein N-linked glycosylation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0042544 +name: melibiose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose." [GOC:jl, ISBN:0198506732] +synonym: "melibiose anabolism" EXACT [] +synonym: "melibiose biosynthesis" EXACT [] +synonym: "melibiose formation" EXACT [] +synonym: "melibiose synthesis" EXACT [] +is_a: GO:0005994 ! melibiose metabolic process +is_a: GO:0046351 ! disaccharide biosynthetic process + +[Term] +id: GO:0042545 +name: cell wall modification +namespace: biological_process +def: "The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly." [GOC:jl] +is_a: GO:0071555 ! cell wall organization + +[Term] +id: GO:0042546 +name: cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:jl, GOC:mah, GOC:mtg_sensu, ISBN:0198506732] +synonym: "cell wall assembly" NARROW [] +is_a: GO:0044085 ! cellular component biogenesis +is_a: GO:0071554 ! cell wall organization or biogenesis +property_value: RO:0002161 NCBITaxon:7742 + +[Term] +id: GO:0042547 +name: cell wall modification involved in multidimensional cell growth +namespace: biological_process +def: "The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth." [GOC:dph, GOC:jl, GOC:tb] +synonym: "cell wall modification during cell expansion" EXACT [] +synonym: "cell wall modification during multidimensional cell growth" RELATED [GOC:dph, GOC:tb] +is_a: GO:0042545 ! cell wall modification +intersection_of: GO:0042545 ! cell wall modification +intersection_of: part_of GO:0009825 ! multidimensional cell growth +relationship: part_of GO:0009825 ! multidimensional cell growth + +[Term] +id: GO:0042548 +name: regulation of photosynthesis, light reaction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis." [GOC:jl] +is_a: GO:0010109 ! regulation of photosynthesis +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019684 ! photosynthesis, light reaction +relationship: regulates GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0042549 +name: photosystem II stabilization +namespace: biological_process +def: "The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis." [GOC:go_curators] +is_a: GO:0042548 ! regulation of photosynthesis, light reaction + +[Term] +id: GO:0042550 +name: photosystem I stabilization +namespace: biological_process +def: "The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis." [GOC:go_curators] +is_a: GO:0042548 ! regulation of photosynthesis, light reaction + +[Term] +id: GO:0042551 +name: neuron maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0048666 ! neuron development + +[Term] +id: GO:0042552 +name: myelination +namespace: biological_process +def: "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GOC:dgh, GOC:mah] +synonym: "myelinogenesis" RELATED [GOC:cjm, HP:0003429] +xref: Wikipedia:Myelin +is_a: GO:0008366 ! axon ensheathment + +[Term] +id: GO:0042554 +name: superoxide anion generation +namespace: biological_process +def: "The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways." [GOC:jl, PMID:12359750] +synonym: "superoxide release" EXACT [GOC:hjd, GOC:mah] +is_a: GO:0006801 ! superoxide metabolic process + +[Term] +id: GO:0042555 +name: MCM complex +namespace: cellular_component +def: "A hexameric protein complex required for the initiation and regulation of DNA replication." [GOC:jl, PMID:11282021] +synonym: "mini-chromosome maintenance complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0097373 ! MCM core complex + +[Term] +id: GO:0042556 +name: eukaryotic elongation factor-2 kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase." [GOC:jl, PMID:11904175] +synonym: "eEF-2 kinase regulator" EXACT [] +is_a: GO:0019887 ! protein kinase regulator activity + +[Term] +id: GO:0042557 +name: eukaryotic elongation factor-2 kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase." [GOC:jl, PMID:11904175] +synonym: "eEF-2 kinase activator" EXACT [] +is_a: GO:0042556 ! eukaryotic elongation factor-2 kinase regulator activity +is_a: GO:0043539 ! protein serine/threonine kinase activator activity + +[Term] +id: GO:0042558 +name: pteridine-containing compound metabolic process +namespace: biological_process +alt_id: GO:0019721 +def: "The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid." [GOC:jl, ISBN:0198506732] +synonym: "pteridine and derivative metabolic process" EXACT [] +synonym: "pteridine and derivative metabolism" EXACT [] +synonym: "pteridine-containing compound metabolism" EXACT [] +synonym: "pterin metabolic process" NARROW [] +synonym: "pterin metabolism" NARROW [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0042559 +name: pteridine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid." [GOC:jl, ISBN:0198506732] +synonym: "pteridine and derivative biosynthesis" EXACT [] +synonym: "pteridine and derivative biosynthetic process" EXACT [] +synonym: "pteridine-containing compound anabolism" EXACT [] +synonym: "pteridine-containing compound biosynthesis" EXACT [] +synonym: "pteridine-containing compound formation" EXACT [] +synonym: "pteridine-containing compound synthesis" EXACT [] +synonym: "pterin biosynthesis" NARROW [] +synonym: "pterin biosynthetic process" NARROW [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042560 +name: pteridine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid." [GOC:jl, ISBN:0198506732] +synonym: "pteridine and derivative catabolic process" EXACT [] +synonym: "pteridine and derivative catabolism" EXACT [] +synonym: "pteridine-containing compound breakdown" EXACT [] +synonym: "pteridine-containing compound catabolism" EXACT [] +synonym: "pteridine-containing compound degradation" EXACT [] +synonym: "pterin catabolic process" NARROW [] +synonym: "pterin catabolism" NARROW [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042561 +name: alpha-amyrin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin." [GOC:jl, MetaCyc:RXN-8434, PMID:10848960] +xref: MetaCyc:RXN-8434 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0042562 +name: hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:jl] +subset: goslim_chembl +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0042563 +name: obsolete importin alpha-subunit nuclear export complex +namespace: cellular_component +def: "OBSOLETE. A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to transport the importin alpha-subunit out of the nucleus through the nuclear pore." [GOC:jl, PMID:9323123, PMID:9323134] +comment: The reason for obsoletion is that these terms include the substrate of the reaction. +is_obsolete: true + +[Term] +id: GO:0042564 +name: NLS-dependent protein nuclear import complex +namespace: cellular_component +def: "A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore." [GOC:jl, PMID:9323123, PMID:9323134, Wikipedia:Importin] +is_a: GO:0031074 ! nucleocytoplasmic transport complex + +[Term] +id: GO:0042565 +name: RNA nuclear export complex +namespace: cellular_component +def: "A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore." [GOC:jl, PMID:9323123] +is_a: GO:0031074 ! nucleocytoplasmic transport complex + +[Term] +id: GO:0042566 +name: hydrogenosome +namespace: cellular_component +def: "A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation." [GOC:jl, PMID:11197234, PMID:11293569] +subset: goslim_pir +xref: Wikipedia:Hydrogenosome +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0042567 +name: insulin-like growth factor ternary complex +namespace: cellular_component +def: "A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development." [GOC:jl, PMID:12239079] +synonym: "IGF ternary complex" EXACT [] +is_a: GO:0016942 ! insulin-like growth factor binding protein complex + +[Term] +id: GO:0042568 +name: insulin-like growth factor binary complex +namespace: cellular_component +def: "A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development." [GOC:jl, PMID:12239079] +synonym: "IGF binary complex" EXACT [] +is_a: GO:0016942 ! insulin-like growth factor binding protein complex + +[Term] +id: GO:0042571 +name: immunoglobulin complex, circulating +namespace: cellular_component +def: "An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component." [GOC:add, ISBN:0781735149] +comment: Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "antibody" EXACT [GOC:add] +xref: Wikipedia:Antibody +is_a: GO:0019814 ! immunoglobulin complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0042572 +name: retinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html, PMID:1924551] +synonym: "retinol metabolism" EXACT [] +synonym: "vitamin A1 alcohol metabolic process" EXACT [] +synonym: "vitamin A1 alcohol metabolism" EXACT [] +synonym: "vitamin A1 metabolic process" EXACT [] +synonym: "vitamin A1 metabolism" EXACT [] +xref: Wikipedia:Retinol +is_a: GO:0001523 ! retinoid metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0042573 +name: retinoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "retinoic acid metabolism" EXACT [] +synonym: "vitamin A1 acid metabolic process" EXACT [] +synonym: "vitamin A1 acid metabolism" EXACT [] +is_a: GO:0001523 ! retinoid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process + +[Term] +id: GO:0042574 +name: retinal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A." [ISBN:0198506732] +synonym: "retinal metabolism" EXACT [] +synonym: "retinaldehyde metabolic process" EXACT [] +synonym: "retinaldehyde metabolism" EXACT [] +is_a: GO:0001523 ! retinoid metabolic process +is_a: GO:0006081 ! cellular aldehyde metabolic process + +[Term] +id: GO:0042575 +name: DNA polymerase complex +namespace: cellular_component +def: "A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA." [GOC:jl, PMID:12045093] +subset: goslim_metagenomics +subset: goslim_pir +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0042576 +name: obsolete aspartyl aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate." [EC:3.4.11.21] +comment: This term was made obsolete because it represents a gene product. +synonym: "aspartyl aminopeptidase activity" EXACT [] +xref: EC:3.4.11.21 +xref: MetaCyc:3.4.11.21-RXN +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0042577 +name: lipid phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate." [GOC:jl] +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0042578 +name: phosphoric ester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3." [GOC:jl] +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0042579 +name: microbody +namespace: cellular_component +def: "Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." [ISBN:0198506732] +subset: goslim_pir +xref: Wikipedia:Microbody +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0042580 +name: mannosome +namespace: cellular_component +def: "A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction." [GOC:jl, PMID:11912051, PMID:9799531] +is_a: GO:0005777 ! peroxisome + +[Term] +id: GO:0042581 +name: specific granule +namespace: cellular_component +def: "Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:jl, ISBN:0721662544, PMID:7334549] +synonym: "secondary granule" EXACT [] +xref: Wikipedia:Specific_granule +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042582 +name: azurophil granule +namespace: cellular_component +def: "Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:jl, PMID:17152095] +synonym: "primary granule" EXACT [] +is_a: GO:0005766 ! primary lysosome +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042583 +name: chromaffin granule +namespace: cellular_component +def: "Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine." [GOC:jl, PMID:19158310, PMID:1961743] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042584 +name: chromaffin granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine." [GOC:jl] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042583 ! chromaffin granule + +[Term] +id: GO:0042585 +name: germinal vesicle +namespace: cellular_component +def: "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity." [GOC:jl, GOC:mtg_sensu, PMID:19019837] +synonym: "primary oocyte nucleus" EXACT [] +is_a: GO:0001674 ! female germ cell nucleus + +[Term] +id: GO:0042586 +name: peptide deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide." [EC:3.5.1.88, GOC:jl] +synonym: "formyl-L-methionyl peptide amidohydrolase activity" EXACT [EC:3.5.1.88] +synonym: "PDF activity" EXACT [EC:3.5.1.88] +synonym: "polypeptide deformylase activity" EXACT [EC:3.5.1.88] +xref: EC:3.5.1.88 +xref: MetaCyc:3.5.1.88-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0042587 +name: glycogen granule +namespace: cellular_component +def: "Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface." [GOC:jl, PMID:12179957] +synonym: "glycogen particle" EXACT [] +xref: NIF_Subcellular:sao1081228141 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0042588 +name: zymogen granule +namespace: cellular_component +def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042589 +name: zymogen granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042588 ! zymogen granule + +[Term] +id: GO:0042590 +name: antigen processing and presentation of exogenous peptide antigen via MHC class I +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "antigen presentation, exogenous antigen via major histocompatibility complex class I" EXACT [] +synonym: "antigen presentation, exogenous antigen via MHC class I" EXACT [] +synonym: "cross presentation" BROAD [] +synonym: "cross priming" BROAD [] +synonym: "cross-presentation" BROAD [] +synonym: "cross-priming" BROAD [] +synonym: "exogenous peptide antigen processing and presentation via MHC class I" EXACT [] +is_a: GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I +is_a: GO:0002478 ! antigen processing and presentation of exogenous peptide antigen + +[Term] +id: GO:0042592 +name: homeostatic process +namespace: biological_process +alt_id: GO:0032844 +alt_id: GO:0032845 +alt_id: GO:0032846 +def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_generic +subset: goslim_mouse +synonym: "activation of homeostatic process" NARROW [] +synonym: "homeostasis" EXACT [] +synonym: "inhibition of homeostatic process" NARROW [] +synonym: "negative regulation of homeostatic process" RELATED [] +synonym: "positive regulation of homeostatic process" RELATED [] +synonym: "regulation of homeostatic process" RELATED [] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0042593 +name: glucose homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell." [GOC:go_curators] +is_a: GO:0033500 ! carbohydrate homeostasis + +[Term] +id: GO:0042594 +name: response to starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment." [GOC:go_curators] +subset: goslim_yeast +is_a: GO:0006950 ! response to stress +is_a: GO:0031667 ! response to nutrient levels + +[Term] +id: GO:0042595 +name: behavioral response to starvation +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment." [GOC:go_curators] +synonym: "behavioural response to starvation" EXACT [] +is_a: GO:0042594 ! response to starvation + +[Term] +id: GO:0042596 +name: fear response +namespace: biological_process +alt_id: GO:0001663 +def: "The response of an organism to a perceived external threat." [GOC:go_curators] +synonym: "physiological fear response" EXACT [] +is_a: GO:0033555 ! multicellular organismal response to stress + +[Term] +id: GO:0042597 +name: periplasmic space +namespace: cellular_component +alt_id: GO:0005620 +def: "The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria)." [GOC:go_curators, GOC:md] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "periplasm" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0042598 +name: obsolete vesicular fraction +namespace: cellular_component +def: "OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized." [GOC:jl] +comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "vesicular fraction" EXACT [] +is_obsolete: true +consider: GO:0031982 + +[Term] +id: GO:0042599 +name: lamellar body +namespace: cellular_component +def: "A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome." [GOC:cjm, GOC:jl, PMID:12243725, Wikipedia:Lamellar_granule] +synonym: "keratinosome" NARROW [] +synonym: "lamellar granule" EXACT [] +synonym: "membrane-coating granule" EXACT [] +synonym: "Odland body" NARROW [] +xref: NIF_Subcellular:sao1379604862 +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042600 +name: egg chorion +namespace: cellular_component +def: "A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish." [GOC:jl, ISBN:0721662544] +comment: Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO. +subset: goslim_pir +is_a: GO:0030312 ! external encapsulating structure + +[Term] +id: GO:0042601 +name: endospore-forming forespore +namespace: cellular_component +def: "Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions." [GOC:jl, GOC:mtg_sensu, ISBN:0697286029] +is_a: GO:0042763 ! intracellular immature spore + +[Term] +id: GO:0042602 +name: riboflavin reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+." [EC:1.5.1.30] +synonym: "flavin reductase activity" RELATED [EC:1.5.1.30] +synonym: "FMN reductase (NADPH) activity" RELATED [EC:1.5.1.30] +synonym: "NADPH dehydrogenase (riboflavin) activity" EXACT [EC:1.5.1.30] +synonym: "NADPH-dependent FMN reductase activity" RELATED [EC:1.5.1.30] +synonym: "NADPH-FMN reductase activity" RELATED [EC:1.5.1.30] +synonym: "NADPH-riboflavin oxidoreductase activity" EXACT [] +synonym: "NADPH-riboflavin reductase activity" EXACT [EC:1.5.1.30] +synonym: "NADPH-specific FMN reductase activity" RELATED [EC:1.5.1.30] +synonym: "NADPH2 dehydrogenase (riboflavin)" EXACT [EC:1.5.1.30] +synonym: "NADPH2:riboflavin oxidoreductase activity" EXACT [EC:1.5.1.30] +synonym: "NADPH:riboflavin oxidoreductase activity" EXACT [EC:1.5.1.30] +synonym: "reduced-riboflavin:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.30] +synonym: "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.5.1.30] +synonym: "riboflavin mononucleotide reductase activity" BROAD [EC:1.5.1.30] +synonym: "riboflavine mononucleotide reductase activity" BROAD [EC:1.5.1.30] +xref: EC:1.5.1.30 +xref: EC:1.5.1.41 +xref: KEGG_REACTION:R05707 +xref: MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN +xref: RHEA:19377 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0042603 +name: capsule +namespace: cellular_component +alt_id: GO:0030113 +alt_id: GO:0042604 +def: "A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication." [GOC:mlg] +xref: Wikipedia:Capsule_(microbiology) +is_a: GO:0030112 ! glycocalyx + +[Term] +id: GO:0042605 +name: peptide antigen binding +namespace: molecular_function +alt_id: GO:0042606 +alt_id: GO:0042607 +def: "Interacting selectively and non-covalently with an antigen peptide." [GOC:add, GOC:jl, GOC:rv] +comment: Note that this term can be used to describe the binding of a peptide to an MHC molecule. +subset: goslim_chembl +synonym: "endogenous peptide antigen binding" NARROW [] +synonym: "exogenous peptide antigen binding" NARROW [] +is_a: GO:0003823 ! antigen binding +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0042608 +name: T cell receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a T cell receptor, the antigen-recognizing receptor on the surface of T cells." [GOC:jl] +synonym: "T lymphocyte receptor binding" EXACT [] +synonym: "T-cell receptor binding" EXACT [] +synonym: "T-lymphocyte receptor binding" EXACT [] +synonym: "TCR binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0042609 +name: CD4 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CD4, a receptor found on the surface of T cells, monocytes and macrophages." [GOC:jl, MSH:D015704] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042610 +name: CD8 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes." [GOC:jl, MSH:D016827] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042611 +name: MHC protein complex +namespace: cellular_component +def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240] +subset: goslim_pir +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0042612 +name: MHC class I protein complex +namespace: cellular_component +def: "A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules." [GOC:add, GOC:jl, ISBN:0120781859, ISBN:0781735149] +comment: See also the cellular component term 'MHC class I peptide loading complex ; GO:0042824'. +is_a: GO:0042611 ! MHC protein complex + +[Term] +id: GO:0042613 +name: MHC class II protein complex +namespace: cellular_component +def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] +is_a: GO:0042611 ! MHC protein complex + +[Term] +id: GO:0042614 +name: CD70 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CD70, a receptor found on the surface of most activated B cells and some activated T cells." [GOC:jl, ISBN:0120781859] +synonym: "CD27 receptor activity" RELATED [] +synonym: "CD27L binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042615 +name: CD154 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with CD154, a receptor found on the surface of some activated lymphocytes." [GOC:jl, ISBN:0120781859] +synonym: "CD40 receptor activity" RELATED [] +synonym: "CD40L binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042616 +name: paclitaxel metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving paclitaxel, an alkaloid compound used as an anticancer treatment." [GOC:jl] +synonym: "paclitaxel metabolism" EXACT [] +synonym: "taxol metabolic process" NARROW [] +synonym: "taxol metabolism" NARROW [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0042617 +name: paclitaxel biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of paclitaxel, an alkaloid compound used as an anticancer treatment." [GOC:jl] +synonym: "paclitaxel anabolism" EXACT [] +synonym: "paclitaxel biosynthesis" EXACT [] +synonym: "paclitaxel formation" EXACT [] +synonym: "paclitaxel synthesis" EXACT [] +synonym: "taxol biosynthesis" NARROW [] +synonym: "taxol biosynthetic process" NARROW [] +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0042616 ! paclitaxel metabolic process + +[Term] +id: GO:0042618 +name: poly-hydroxybutyrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells." [GOC:jl\,PMID\:18640095] +synonym: "PHB metabolic process" EXACT [] +synonym: "PHB metabolism" EXACT [] +synonym: "poly-hydroxybutyrate metabolism" EXACT [] +is_a: GO:1901440 ! poly(hydroxyalkanoate) metabolic process + +[Term] +id: GO:0042619 +name: poly-hydroxybutyrate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells." [GOC:jl, PMID:18640095] +synonym: "PHB biosynthesis" EXACT [] +synonym: "PHB biosynthetic process" EXACT [] +synonym: "poly-hydroxybutyrate anabolism" EXACT [] +synonym: "poly-hydroxybutyrate biosynthesis" EXACT [] +synonym: "poly-hydroxybutyrate formation" EXACT [] +synonym: "poly-hydroxybutyrate synthesis" EXACT [] +is_a: GO:0042618 ! poly-hydroxybutyrate metabolic process +is_a: GO:1901441 ! poly(hydroxyalkanoate) biosynthetic process + +[Term] +id: GO:0042620 +name: poly(3-hydroxyalkanoate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria." [GOC:jl, PMID:9925580] +subset: goslim_pir +synonym: "PHA metabolic process" BROAD [] +synonym: "PHA metabolism" BROAD [] +synonym: "poly(3-hydroxyalkanoate) metabolism" EXACT [] +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0042621 +name: poly(3-hydroxyalkanoate) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria." [GOC:jl, PMID:9925580] +synonym: "PHA biosynthesis" BROAD [] +synonym: "PHA biosynthetic process" BROAD [] +synonym: "poly(3-hydroxyalkanoate) anabolism" EXACT [] +synonym: "poly(3-hydroxyalkanoate) biosynthesis" EXACT [] +synonym: "poly(3-hydroxyalkanoate) formation" EXACT [] +synonym: "poly(3-hydroxyalkanoate) synthesis" EXACT [] +is_a: GO:0042620 ! poly(3-hydroxyalkanoate) metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0042622 +name: photoreceptor outer segment membrane +namespace: cellular_component +def: "The membrane surrounding the outer segment of a vertebrate photoreceptor." [GOC:jl] +is_a: GO:0060170 ! ciliary membrane +relationship: part_of GO:0001750 ! photoreceptor outer segment + +[Term] +id: GO:0042624 +name: obsolete ATPase activity, uncoupled +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction." [PMID:12912988] +comment: The reason for obsoletion is that the there is no convincing example of a protein with this function. +is_obsolete: true + +[Term] +id: GO:0042625 +name: ATPase-coupled ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +synonym: "ATP-dependent ion transmembrane transporter activity" EXACT [] +synonym: "ATPase activity, coupled to transmembrane movement of ions" EXACT [] +synonym: "ATPase coupled ion transmembrane transporter activity" EXACT [] +is_a: GO:0022853 ! active ion transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0042626 +name: ATPase-coupled transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015405 +alt_id: GO:0016820 +def: "Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729] +synonym: "ATP-coupled transmembrane transporter activity" EXACT [] +synonym: "ATP-dependent transmembrane transporter activity" EXACT [] +synonym: "ATPase activity, coupled to transmembrane movement of substances" EXACT [] +synonym: "hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances" NARROW [] +synonym: "P-P-bond-hydrolysis-driven transmembrane transporter activity" BROAD [] +synonym: "P-P-bond-hydrolysis-driven transporter" BROAD [] +xref: EC:7.2.2 +xref: Reactome:R-HSA-266070 "LTC4 is exported from the cytosol by ABCC1" +xref: Reactome:R-HSA-5223313 "ABCD4 may transport Cbl from lysosomal lumen to cytosol" +xref: Reactome:R-HSA-5362459 "VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol" +xref: Reactome:R-HSA-5387389 "Hh processing variants are translocated to the cytosol in a VCP-dependent manner" +xref: Reactome:R-HSA-5683325 "Defective ABCD4 does not transport Cbl from lysosomal lumen to cytosol" +is_a: GO:0015399 ! primary active transmembrane transporter activity +relationship: has_part GO:0016887 ! ATPase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14642 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17373 xsd:anyURI + +[Term] +id: GO:0042627 +name: chylomicron +namespace: cellular_component +def: "A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues." [GOC:jl, GOC:rl, PMID:10580165] +xref: Wikipedia:Chylomicron +is_a: GO:0034358 ! plasma lipoprotein particle + +[Term] +id: GO:0042628 +name: mating plug formation +namespace: biological_process +def: "The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males." [GOC:jl, PMID:11267893] +synonym: "copulatory plug biosynthesis" EXACT [] +synonym: "copulatory plug deposition" EXACT [] +synonym: "copulatory plug formation" EXACT [] +synonym: "mating plug deposition" EXACT [] +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007320 ! insemination + +[Term] +id: GO:0042629 +name: mast cell granule +namespace: cellular_component +def: "Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase." [GOC:jl, http://www.ijp-online.com/archives/1969/001/02/r0000-0000tc.htm, PMID:12360215] +is_a: GO:0005764 ! lysosome + +[Term] +id: GO:0042630 +name: behavioral response to water deprivation +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of deprivation of water." [GOC:jl] +synonym: "behavioral response to drought" EXACT [] +synonym: "behavioral response to thirst" EXACT [] +synonym: "behavioural response to water deprivation" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0009414 ! response to water deprivation + +[Term] +id: GO:0042631 +name: cellular response to water deprivation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water." [GOC:go_curators] +synonym: "cellular response to drought" EXACT [] +is_a: GO:0009414 ! response to water deprivation +is_a: GO:0031668 ! cellular response to extracellular stimulus +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0071462 ! cellular response to water stimulus + +[Term] +id: GO:0042632 +name: cholesterol homeostasis +namespace: biological_process +alt_id: GO:2000188 +alt_id: GO:2000189 +def: "Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell." [GOC:go_curators] +synonym: "positive regulation of cholesterol homeostasis" RELATED [] +synonym: "regulation of cholesterol homeostasis" RELATED [] +is_a: GO:0055092 ! sterol homeostasis + +[Term] +id: GO:0042633 +name: hair cycle +namespace: biological_process +def: "The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:go_curators, PMID:12230507] +is_a: GO:0042303 ! molting cycle +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0042634 +name: regulation of hair cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair." [GOC:go_curators, PMID:12230507] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042633 ! hair cycle +relationship: regulates GO:0042633 ! hair cycle + +[Term] +id: GO:0042635 +name: positive regulation of hair cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair." [GOC:go_curators, PMID:12230507] +synonym: "activation of hair cycle" NARROW [] +synonym: "stimulation of hair cycle" NARROW [] +synonym: "up regulation of hair cycle" EXACT [] +synonym: "up-regulation of hair cycle" EXACT [] +synonym: "upregulation of hair cycle" EXACT [] +is_a: GO:0042634 ! regulation of hair cycle +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042633 ! hair cycle +relationship: positively_regulates GO:0042633 ! hair cycle + +[Term] +id: GO:0042636 +name: negative regulation of hair cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair." [GOC:go_curators, PMID:12230507] +synonym: "down regulation of hair cycle" EXACT [] +synonym: "down-regulation of hair cycle" EXACT [] +synonym: "downregulation of hair cycle" EXACT [] +synonym: "inhibition of hair cycle" NARROW [] +is_a: GO:0042634 ! regulation of hair cycle +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042633 ! hair cycle +relationship: negatively_regulates GO:0042633 ! hair cycle + +[Term] +id: GO:0042637 +name: catagen +namespace: biological_process +def: "The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced." [PMID:12535193] +subset: gocheck_do_not_annotate +synonym: "hair regression" NARROW [] +is_a: GO:0044851 ! hair cycle phase +relationship: part_of GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0042638 +name: exogen +namespace: biological_process +def: "The shedding phase of the hair cycle." [PMID:12230507] +subset: gocheck_do_not_annotate +synonym: "hair shedding" NARROW [] +is_a: GO:0044851 ! hair cycle phase +relationship: part_of GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0042639 +name: telogen +namespace: biological_process +def: "The resting phase of hair cycle." [PMID:12230507] +subset: gocheck_do_not_annotate +synonym: "hair resting phase" NARROW [] +is_a: GO:0044851 ! hair cycle phase + +[Term] +id: GO:0042640 +name: anagen +namespace: biological_process +def: "The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair." [PMID:12230507] +subset: gocheck_do_not_annotate +synonym: "hair growth" RELATED [] +is_a: GO:0044851 ! hair cycle phase +relationship: part_of GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0042641 +name: actomyosin +namespace: cellular_component +def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] +synonym: "actomyosin complex" EXACT [] +synonym: "actomyosin structure" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0042642 +name: actomyosin, myosin complex part +namespace: cellular_component +def: "The myosin part of any complex of actin, myosin, and accessory proteins." [GOC:go_curators] +is_a: GO:0016459 ! myosin complex +intersection_of: GO:0016459 ! myosin complex +intersection_of: part_of GO:0042641 ! actomyosin +relationship: part_of GO:0042641 ! actomyosin + +[Term] +id: GO:0042643 +name: actomyosin, actin portion +namespace: cellular_component +def: "The actin part of any complex of actin, myosin, and accessory proteins." [GOC:go_curators] +is_a: GO:0005884 ! actin filament +intersection_of: GO:0005884 ! actin filament +intersection_of: part_of GO:0042641 ! actomyosin +relationship: part_of GO:0042641 ! actomyosin + +[Term] +id: GO:0042644 +name: chloroplast nucleoid +namespace: cellular_component +def: "The region of a chloroplast to which the DNA is confined." [GOC:jl] +is_a: GO:0042646 ! plastid nucleoid +intersection_of: GO:0009295 ! nucleoid +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0042645 +name: mitochondrial nucleoid +namespace: cellular_component +def: "The region of a mitochondrion to which the DNA is confined." [GOC:jl] +is_a: GO:0009295 ! nucleoid +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +intersection_of: GO:0009295 ! nucleoid +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0042646 +name: plastid nucleoid +namespace: cellular_component +def: "The region of a plastid to which the DNA is confined." [GOC:jl] +is_a: GO:0009295 ! nucleoid +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +intersection_of: GO:0009295 ! nucleoid +intersection_of: part_of GO:0009536 ! plastid +relationship: part_of GO:0009532 ! plastid stroma + +[Term] +id: GO:0042647 +name: proplastid nucleoid +namespace: cellular_component +def: "The region of a proplastid to which the DNA is confined." [GOC:jl] +is_a: GO:0042646 ! plastid nucleoid +intersection_of: GO:0009295 ! nucleoid +intersection_of: part_of GO:0009537 ! proplastid +relationship: part_of GO:0009571 ! proplastid stroma + +[Term] +id: GO:0042648 +name: chloroplast chromosome +namespace: cellular_component +def: "A circular DNA molecule containing chloroplast encoded genes." [GOC:jl] +is_a: GO:0009508 ! plastid chromosome +intersection_of: GO:0005694 ! chromosome +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0042644 ! chloroplast nucleoid + +[Term] +id: GO:0042649 +name: prothylakoid +namespace: cellular_component +def: "Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light." [GOC:jl, PMID:11532175] +is_a: GO:0031976 ! plastid thylakoid +relationship: part_of GO:0009513 ! etioplast + +[Term] +id: GO:0042650 +name: prothylakoid membrane +namespace: cellular_component +def: "The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes." [GOC:jl, PMID:11532175] +is_a: GO:0055035 ! plastid thylakoid membrane +relationship: part_of GO:0042649 ! prothylakoid + +[Term] +id: GO:0042651 +name: thylakoid membrane +namespace: cellular_component +def: "The pigmented membrane of any thylakoid." [GOC:jl, GOC:pr] +is_a: GO:0034357 ! photosynthetic membrane + +[Term] +id: GO:0042652 +name: mitochondrial respiratory chain complex I, peripheral segment +namespace: cellular_component +def: "The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix." [GOC:jid, GOC:mtg_sensu, ISBN:0716749556] +synonym: "NADH dehydrogenase (ubiquinone) complex, peripheral segment" BROAD [] +synonym: "NADH-Q oxidoreductase complex, peripheral segment" BROAD [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0005747 ! mitochondrial respiratory chain complex I + +[Term] +id: GO:0042653 +name: mitochondrial respiratory chain complex I, membrane segment +namespace: cellular_component +def: "The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix." [GOC:jid, GOC:mtg_sensu, ISBN:0716749556] +synonym: "NADH-Q oxidoreductase complex, membrane segment" BROAD [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0005747 ! mitochondrial respiratory chain complex I + +[Term] +id: GO:0042654 +name: ecdysis-triggering hormone receptor activity +namespace: molecular_function +def: "Combining with ecdysis-triggering hormone to initiate a change in cell activity." [GOC:ma] +synonym: "ecdysis-triggering hormone binding" NARROW [] +synonym: "ETH receptor" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: has_part GO:0042562 ! hormone binding + +[Term] +id: GO:0042655 +name: activation of JNKKK activity +namespace: biological_process +def: "The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity." [GOC:bf] +synonym: "activation of JUN kinase kinase kinase activity" EXACT [] +synonym: "positive regulation of JUNKKK activity" BROAD [] +is_a: GO:0000185 ! activation of MAPKKK activity +is_a: GO:0043507 ! positive regulation of JUN kinase activity +relationship: part_of GO:0007254 ! JNK cascade +relationship: positively_regulates GO:0004706 ! JUN kinase kinase kinase activity + +[Term] +id: GO:0042656 +name: JUN kinase kinase kinase kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs)." [GOC:bf] +synonym: "JUNKKKK activity" EXACT [] +is_a: GO:0008349 ! MAP kinase kinase kinase kinase activity +relationship: part_of GO:0042655 ! activation of JNKKK activity + +[Term] +id: GO:0042657 +name: MHC class II protein binding, via lateral surface +namespace: molecular_function +def: "Interacting selectively and non-covalently with the lateral surface of major histocompatibility complex class II molecules." [GOC:jl] +synonym: "major histocompatibility complex class II protein binding, via lateral surface" EXACT [] +is_a: GO:0042289 ! MHC class II protein binding + +[Term] +id: GO:0042658 +name: MHC class II protein binding, via antigen binding groove +namespace: molecular_function +def: "Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules." [GOC:jl] +synonym: "major histocompatibility complex class II protein binding, via antigen binding groove" EXACT [] +is_a: GO:0042289 ! MHC class II protein binding +relationship: part_of GO:0023026 ! MHC class II protein complex binding + +[Term] +id: GO:0042659 +name: regulation of cell fate specification +namespace: biological_process +def: "Any process that mediates the adoption of a specific fate by a cell." [GOC:go_curators] +is_a: GO:0010453 ! regulation of cell fate commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001708 ! cell fate specification +relationship: regulates GO:0001708 ! cell fate specification + +[Term] +id: GO:0042660 +name: positive regulation of cell fate specification +namespace: biological_process +def: "Any process that activates or enables a cell to adopt a specific fate." [GOC:go_curators] +synonym: "activation of cell fate specification" NARROW [] +synonym: "stimulation of cell fate specification" NARROW [] +synonym: "up regulation of cell fate specification" EXACT [] +synonym: "up-regulation of cell fate specification" EXACT [] +synonym: "upregulation of cell fate specification" EXACT [] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:0042659 ! regulation of cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001708 ! cell fate specification +relationship: positively_regulates GO:0001708 ! cell fate specification + +[Term] +id: GO:0042661 +name: regulation of mesodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesoderm cell fate specification." [GOC:go_curators] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:1905770 ! regulation of mesodermal cell differentiation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007501 ! mesodermal cell fate specification +relationship: regulates GO:0007501 ! mesodermal cell fate specification + +[Term] +id: GO:0042662 +name: negative regulation of mesodermal cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification." [GOC:go_curators] +synonym: "down regulation of mesodermal cell fate specification" EXACT [] +synonym: "down-regulation of mesodermal cell fate specification" EXACT [] +synonym: "downregulation of mesodermal cell fate specification" EXACT [] +synonym: "inhibition of mesodermal cell fate specification" NARROW [] +synonym: "suppression of mesodermal cell fate" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +is_a: GO:1905771 ! negative regulation of mesodermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007501 ! mesodermal cell fate specification +relationship: negatively_regulates GO:0007501 ! mesodermal cell fate specification + +[Term] +id: GO:0042663 +name: regulation of endodermal cell fate specification +namespace: biological_process +def: "Any process that mediates the specification of a cell into an endoderm cell." [GOC:go_curators] +synonym: "regulation of endoderm cell fate specification" EXACT [] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:1903224 ! regulation of endodermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001714 ! endodermal cell fate specification +relationship: regulates GO:0001714 ! endodermal cell fate specification + +[Term] +id: GO:0042664 +name: negative regulation of endodermal cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from specifying into an endoderm cell." [GOC:go_curators] +synonym: "down regulation of endodermal cell fate specification" EXACT [] +synonym: "down-regulation of endodermal cell fate specification" EXACT [] +synonym: "downregulation of endodermal cell fate specification" EXACT [] +synonym: "inhibition of endodermal cell fate specification" NARROW [] +synonym: "negative regulation of endoderm cell fate specification" EXACT [] +synonym: "suppression of endoderm cell fate" EXACT [] +synonym: "suppression of endodermal cell fate" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042663 ! regulation of endodermal cell fate specification +is_a: GO:1903225 ! negative regulation of endodermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001714 ! endodermal cell fate specification +relationship: negatively_regulates GO:0001714 ! endodermal cell fate specification + +[Term] +id: GO:0042665 +name: regulation of ectodermal cell fate specification +namespace: biological_process +def: "Any process that mediates the specification of a cell into an ectoderm cell." [GOC:go_curators] +synonym: "regulation of ectoderm cell fate specification" EXACT [] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:2000383 ! regulation of ectoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001715 ! ectodermal cell fate specification +relationship: regulates GO:0001715 ! ectodermal cell fate specification + +[Term] +id: GO:0042666 +name: negative regulation of ectodermal cell fate specification +namespace: biological_process +def: "Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell." [GOC:go_curators] +synonym: "down regulation of ectodermal cell fate specification" EXACT [] +synonym: "down-regulation of ectodermal cell fate specification" EXACT [] +synonym: "downregulation of ectodermal cell fate specification" EXACT [] +synonym: "inhibition of ectodermal cell fate specification" NARROW [] +synonym: "negative regulation of ectoderm cell fate specification" EXACT [] +synonym: "suppression of ectoderm cell fate" EXACT [] +synonym: "suppression of ectodermal cell fate" EXACT [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042665 ! regulation of ectodermal cell fate specification +is_a: GO:2000384 ! negative regulation of ectoderm development +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001715 ! ectodermal cell fate specification +relationship: negatively_regulates GO:0001715 ! ectodermal cell fate specification + +[Term] +id: GO:0042667 +name: auditory receptor cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] +synonym: "auditory hair cell fate specification" EXACT [] +is_a: GO:0048665 ! neuron fate specification +relationship: part_of GO:0009912 ! auditory receptor cell fate commitment + +[Term] +id: GO:0042668 +name: auditory receptor cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +synonym: "auditory hair cell fate determination" EXACT [] +is_a: GO:0048664 ! neuron fate determination +relationship: part_of GO:0009912 ! auditory receptor cell fate commitment + +[Term] +id: GO:0042669 +name: regulation of inner ear auditory receptor cell fate specification +namespace: biological_process +def: "Any process that mediates the specification of a cell into an auditory hair cell." [GOC:go_curators] +synonym: "regulation of auditory hair cell fate specification" EXACT [] +synonym: "regulation of inner ear auditory receptor cell fate specification" RELATED [] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:0045607 ! regulation of inner ear auditory receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042667 ! auditory receptor cell fate specification +relationship: regulates GO:0042667 ! auditory receptor cell fate specification + +[Term] +id: GO:0042670 +name: retinal cone cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators] +is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation + +[Term] +id: GO:0042671 +name: retinal cone cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] +is_a: GO:0043703 ! photoreceptor cell fate determination +relationship: part_of GO:0046551 ! retinal cone cell fate commitment + +[Term] +id: GO:0042672 +name: retinal cone cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] +is_a: GO:0043704 ! photoreceptor cell fate specification +relationship: part_of GO:0046551 ! retinal cone cell fate commitment + +[Term] +id: GO:0042673 +name: regulation of retinal cone cell fate specification +namespace: biological_process +def: "Any process that mediates the specification of a cell into a retinal cone cell." [GOC:go_curators] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:0060222 ! regulation of retinal cone cell fate commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042672 ! retinal cone cell fate specification +relationship: regulates GO:0042672 ! retinal cone cell fate specification + +[Term] +id: GO:0042675 +name: compound eye cone cell differentiation +namespace: biological_process +alt_id: GO:0042674 +def: "The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye." [GOC:mtg_sensu] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0042676 +name: compound eye cone cell fate commitment +namespace: biological_process +alt_id: GO:0007466 +def: "The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type." [GOC:mtg_sensu] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0042675 ! compound eye cone cell differentiation + +[Term] +id: GO:0042679 +name: compound eye cone cell fate specification +namespace: biological_process +alt_id: GO:0042678 +def: "The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:mtg_sensu] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0042676 ! compound eye cone cell fate commitment + +[Term] +id: GO:0042680 +name: compound eye cone cell fate determination +namespace: biological_process +alt_id: GO:0042677 +def: "The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:mtg_sensu] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0042676 ! compound eye cone cell fate commitment + +[Term] +id: GO:0042682 +name: regulation of compound eye cone cell fate specification +namespace: biological_process +alt_id: GO:0042681 +def: "Any process that mediates the specification of a cell into a compound eye cone cell." [GOC:mtg_sensu] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042679 ! compound eye cone cell fate specification +relationship: regulates GO:0042679 ! compound eye cone cell fate specification + +[Term] +id: GO:0042683 +name: negative regulation of compound eye cone cell fate specification +namespace: biological_process +alt_id: GO:0010000 +def: "Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell." [GOC:mtg_sensu] +synonym: "down regulation of cone cell fate specification" BROAD [] +synonym: "down-regulation of cone cell fate specification" BROAD [] +synonym: "downregulation of cone cell fate specification" BROAD [] +synonym: "inhibition of cone cell fate specification" BROAD [] +synonym: "suppression of cone cell fate" BROAD [] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0042682 ! regulation of compound eye cone cell fate specification +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042679 ! compound eye cone cell fate specification +relationship: negatively_regulates GO:0042679 ! compound eye cone cell fate specification + +[Term] +id: GO:0042684 +name: cardioblast cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0010002 ! cardioblast differentiation + +[Term] +id: GO:0042685 +name: cardioblast cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +is_a: GO:0060912 ! cardiac cell fate specification +relationship: part_of GO:0042684 ! cardioblast cell fate commitment + +[Term] +id: GO:0042686 +name: regulation of cardioblast cell fate specification +namespace: biological_process +def: "Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] +is_a: GO:0051890 ! regulation of cardioblast differentiation +is_a: GO:2000043 ! regulation of cardiac cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042685 ! cardioblast cell fate specification +relationship: regulates GO:0042685 ! cardioblast cell fate specification + +[Term] +id: GO:0042688 +name: crystal cell differentiation +namespace: biological_process +def: "The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm] +is_a: GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0042689 +name: regulation of crystal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] +is_a: GO:0045610 ! regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042688 ! crystal cell differentiation +relationship: regulates GO:0042688 ! crystal cell differentiation + +[Term] +id: GO:0042690 +name: negative regulation of crystal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] +synonym: "down regulation of crystal cell differentiation" EXACT [] +synonym: "down-regulation of crystal cell differentiation" EXACT [] +synonym: "downregulation of crystal cell differentiation" EXACT [] +synonym: "inhibition of crystal cell differentiation" NARROW [] +is_a: GO:0042689 ! regulation of crystal cell differentiation +is_a: GO:0045611 ! negative regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042688 ! crystal cell differentiation +relationship: negatively_regulates GO:0042688 ! crystal cell differentiation + +[Term] +id: GO:0042691 +name: positive regulation of crystal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] +synonym: "activation of crystal cell differentiation" NARROW [] +synonym: "stimulation of crystal cell differentiation" NARROW [] +synonym: "up regulation of crystal cell differentiation" EXACT [] +synonym: "up-regulation of crystal cell differentiation" EXACT [] +synonym: "upregulation of crystal cell differentiation" EXACT [] +is_a: GO:0042689 ! regulation of crystal cell differentiation +is_a: GO:0045612 ! positive regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042688 ! crystal cell differentiation +relationship: positively_regulates GO:0042688 ! crystal cell differentiation + +[Term] +id: GO:0042692 +name: muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators] +synonym: "myogenesis" RELATED [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0061061 ! muscle structure development + +[Term] +id: GO:0042693 +name: muscle cell fate commitment +namespace: biological_process +def: "The process in which the cellular identity of muscle cells is acquired and determined." [CL:0000187, GOC:go_curators] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0042694 +name: muscle cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [CL:0000187, GOC:go_curators] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0042693 ! muscle cell fate commitment + +[Term] +id: GO:0042695 +name: thelarche +namespace: biological_process +def: "The beginning of development of the breasts in the female." [GOC:curators, PMID:19117864] +xref: Wikipedia:Thelarche +is_a: GO:0046543 ! development of secondary female sexual characteristics +relationship: part_of GO:0030879 ! mammary gland development + +[Term] +id: GO:0042696 +name: menarche +namespace: biological_process +def: "The beginning of the menstrual cycle; the first menstrual cycle in an individual." [GOC:curators, PMID:16311040] +subset: gocheck_do_not_annotate +xref: Wikipedia:Menarche +is_a: GO:0022601 ! menstrual cycle phase + +[Term] +id: GO:0042697 +name: menopause +namespace: biological_process +def: "Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50." [GOC:curators, PMID:18495681] +subset: gocheck_do_not_annotate +xref: Wikipedia:Menopause +is_a: GO:0022601 ! menstrual cycle phase +relationship: part_of GO:0010259 ! multicellular organism aging + +[Term] +id: GO:0042698 +name: ovulation cycle +namespace: biological_process +def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544] +is_a: GO:0048511 ! rhythmic process +is_a: GO:0048609 ! multicellular organismal reproductive process + +[Term] +id: GO:0042699 +name: follicle-stimulating hormone signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by follicle-stimulating hormone." [GOC:dph] +synonym: "follicle stimulating hormone signaling pathway" EXACT [] +synonym: "follicle stimulating hormone signalling pathway" EXACT [] +synonym: "follicle-stimulating hormone signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022602 ! ovulation cycle process +relationship: part_of GO:0001541 ! ovarian follicle development + +[Term] +id: GO:0042700 +name: luteinizing hormone signaling pathway +namespace: biological_process +def: "The series of molecular signals mediated by luteinizing hormone." [GOC:dph] +synonym: "luteinizing hormone signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0042701 +name: progesterone secretion +namespace: biological_process +def: "The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta." [GOC:jl, ISBN:0395825172] +is_a: GO:0015893 ! drug transport +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0035929 ! steroid hormone secretion +relationship: part_of GO:0001553 ! luteinization + +[Term] +id: GO:0042702 +name: uterine wall growth +namespace: biological_process +def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:0040007 ! growth +relationship: part_of GO:0001553 ! luteinization + +[Term] +id: GO:0042703 +name: menstruation +namespace: biological_process +def: "The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus." [GOC:curators, PMID:8693059] +subset: gocheck_do_not_annotate +xref: Wikipedia:Menstruation +is_a: GO:0022601 ! menstrual cycle phase + +[Term] +id: GO:0042704 +name: uterine wall breakdown +namespace: biological_process +def: "The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels." [GOC:dph] +is_a: GO:0022602 ! ovulation cycle process +relationship: happens_during GO:0042703 ! menstruation + +[Term] +id: GO:0042705 +name: ocellus photoreceptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus." [GOC:go_curators] +is_a: GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0042706 +name: eye photoreceptor cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments." [GOC:mtg_sensu] +is_a: GO:0046552 ! photoreceptor cell fate commitment +relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation + +[Term] +id: GO:0042707 +name: ocellus photoreceptor cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments." [GOC:mtg_sensu] +is_a: GO:0046552 ! photoreceptor cell fate commitment +relationship: part_of GO:0042705 ! ocellus photoreceptor cell differentiation + +[Term] +id: GO:0042708 +name: obsolete elastase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of elastin." [ISBN:0198506732] +comment: This term was made obsolete because it represents a gene product. +synonym: "elastase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004175 + +[Term] +id: GO:0042709 +name: succinate-CoA ligase complex +namespace: cellular_component +def: "A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP." [EC:6.2.1.4, EC:6.2.1.5, GOC:jl] +is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0042710 +name: biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, PMID:11932229] +subset: gocheck_do_not_annotate +subset: gocheck_do_not_manually_annotate +subset: goslim_candida +subset: goslim_pir +is_a: GO:0098630 ! aggregation of unicellular organisms +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17727 xsd:anyURI + +[Term] +id: GO:0042711 +name: maternal behavior +namespace: biological_process +def: "Female behaviors associated with the care and rearing of offspring." [GOC:curators] +synonym: "maternal behaviour" EXACT [] +is_a: GO:0060746 ! parental behavior + +[Term] +id: GO:0042712 +name: paternal behavior +namespace: biological_process +def: "Male behaviors associated with the care and rearing offspring." [GOC:go_curators] +synonym: "paternal behaviour" EXACT [] +is_a: GO:0060746 ! parental behavior + +[Term] +id: GO:0042713 +name: sperm ejaculation +namespace: biological_process +def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007320 ! insemination + +[Term] +id: GO:0042714 +name: dosage compensation complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes." [GOC:jl, PMID:11102361, PMID:12672493] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007549 ! dosage compensation + +[Term] +id: GO:0042715 +name: dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans." [GOC:jl, PMID:11102361, PMID:12672493] +synonym: "dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome" RELATED [GOC:dph, GOC:tb] +is_a: GO:0042714 ! dosage compensation complex assembly +is_a: GO:0065004 ! protein-DNA complex assembly +intersection_of: GO:0042714 ! dosage compensation complex assembly +intersection_of: part_of GO:0042464 ! dosage compensation by hypoactivation of X chromosome +relationship: part_of GO:0042464 ! dosage compensation by hypoactivation of X chromosome + +[Term] +id: GO:0042716 +name: plasma membrane-derived chromatophore +namespace: cellular_component +def: "A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria." [GOC:jl, ISBN:0395825172, PMID:11867431] +comment: Note that this structure is distinct from the chromoplast of plants, which is also sometimes called a chromatophore; it also should not be confused with the specialized pigment-producing cells known as chromatophores, found in fish and amphibian skin. +synonym: "chromatophore vesicle" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0042717 +name: plasma membrane-derived chromatophore membrane +namespace: cellular_component +def: "The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles." [GOC:jl, GOC:mah, ISBN:0395825172, PMID:11867431] +is_a: GO:0034357 ! photosynthetic membrane +relationship: part_of GO:0042716 ! plasma membrane-derived chromatophore + +[Term] +id: GO:0042718 +name: yolk granule +namespace: cellular_component +def: "Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed." [GOC:jl, PMID:18046696, PMID:6337890] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060417 ! yolk + +[Term] +id: GO:0042719 +name: mitochondrial intermembrane space protein transporter complex +namespace: cellular_component +def: "Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane." [PMID:12581629] +synonym: "Tim9-Tim10 complex" NARROW [] +is_a: GO:0098798 ! mitochondrial protein complex +is_a: GO:1990351 ! transporter complex +relationship: part_of GO:0005758 ! mitochondrial intermembrane space + +[Term] +id: GO:0042720 +name: mitochondrial inner membrane peptidase complex +namespace: cellular_component +def: "Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space." [PMID:10821182, PMID:12191769] +synonym: "IMP" NARROW [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex + +[Term] +id: GO:0042721 +name: TIM22 mitochondrial import inner membrane insertion complex +namespace: cellular_component +def: "A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12." [PMID:12191765, PMID:27554484] +synonym: "mitochondrial inner membrane protein insertion complex" EXACT [] +synonym: "mitochondrial protein translocase complex" BROAD [] +synonym: "Tim22 complex" EXACT [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex + +[Term] +id: GO:0042722 +name: alpha-beta T cell activation by superantigen +namespace: biological_process +def: "The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region." [GOC:jl] +synonym: "alpha-beta T lymphocyte activation by superantigen" EXACT [] +synonym: "alpha-beta T-cell activation by superantigen" EXACT [] +synonym: "alpha-beta T-lymphocyte activation by superantigen" EXACT [] +is_a: GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0042723 +name: thiamine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it." [GOC:jl] +synonym: "thiamin and derivative metabolic process" EXACT [] +synonym: "thiamin and derivative metabolism" EXACT [] +synonym: "thiamin-containing compound metabolic process" EXACT [] +synonym: "thiamine and derivative metabolic process" EXACT [] +synonym: "thiamine and derivative metabolism" EXACT [] +synonym: "thiamine-containing compound metabolism" EXACT [] +synonym: "vitamin B1 and derivative metabolic process" EXACT [] +synonym: "vitamin B1 and derivative metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process + +[Term] +id: GO:0042724 +name: thiamine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds." [GOC:jl] +synonym: "thiamin and derivative biosynthesis" EXACT [] +synonym: "thiamin and derivative biosynthetic process" EXACT [] +synonym: "thiamin-containing compound biosynthetic process" EXACT [] +synonym: "thiamine and derivative biosynthesis" EXACT [] +synonym: "thiamine and derivative biosynthetic process" EXACT [] +synonym: "thiamine-containing compound anabolism" EXACT [] +synonym: "thiamine-containing compound biosynthesis" EXACT [] +synonym: "thiamine-containing compound formation" EXACT [] +synonym: "thiamine-containing compound synthesis" EXACT [] +synonym: "vitamin B1 and derivative biosynthesis" EXACT [] +synonym: "vitamin B1 and derivative biosynthetic process" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0042723 ! thiamine-containing compound metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process + +[Term] +id: GO:0042725 +name: thiamine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it." [GOC:jl] +synonym: "thiamin and derivative catabolic process" EXACT [] +synonym: "thiamin and derivative catabolism" EXACT [] +synonym: "thiamin-containing compound catabolic process" EXACT [] +synonym: "thiamine and derivative catabolic process" EXACT [] +synonym: "thiamine and derivative catabolism" EXACT [] +synonym: "thiamine-containing compound breakdown" EXACT [] +synonym: "thiamine-containing compound catabolism" EXACT [] +synonym: "thiamine-containing compound degradation" EXACT [] +synonym: "vitamin B1 and derivative catabolic process" EXACT [] +synonym: "vitamin B1 and derivative catabolism" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042723 ! thiamine-containing compound metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0042726 +name: flavin-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position." [GOC:jl, GOC:mah] +synonym: "flavin-containing compound metabolism" EXACT [] +synonym: "riboflavin and derivative metabolic process" RELATED [] +synonym: "riboflavin and derivative metabolism" RELATED [] +synonym: "vitamin B2 and derivative metabolic process" RELATED [] +synonym: "vitamin B2 and derivative metabolism" RELATED [] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0042727 +name: flavin-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position." [GOC:jl, GOC:mah] +synonym: "flavin-containing compound anabolism" EXACT [] +synonym: "flavin-containing compound biosynthesis" EXACT [] +synonym: "flavin-containing compound formation" EXACT [] +synonym: "flavin-containing compound synthesis" EXACT [] +synonym: "riboflavin and derivative biosynthesis" RELATED [] +synonym: "riboflavin and derivative biosynthetic process" RELATED [] +synonym: "vitamin B2 and derivative biosynthesis" RELATED [] +synonym: "vitamin B2 and derivative biosynthetic process" RELATED [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042726 ! flavin-containing compound metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042728 +name: flavin-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position." [GOC:jl, GOC:mah] +synonym: "flavin-containing compound catabolic process breakdown" EXACT [] +synonym: "flavin-containing compound catabolic process degradation" EXACT [] +synonym: "flavin-containing compound catabolism" EXACT [] +synonym: "riboflavin and derivative catabolic process" RELATED [] +synonym: "riboflavin and derivative catabolism" RELATED [] +synonym: "vitamin B2 and derivative catabolic process" RELATED [] +synonym: "vitamin B2 and derivative catabolism" RELATED [] +is_a: GO:0042726 ! flavin-containing compound metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042729 +name: DASH complex +namespace: cellular_component +alt_id: GO:0043925 +alt_id: GO:0043926 +def: "A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability." [GOC:jl, GOC:vw, http://www.wikigenes.org/e/gene/e/853090.html, PMID:11782438, PMID:11799062, PMID:15632076, PMID:15640796] +comment: Note that this complex is conserved in fungi but has not been observed in metazoans. +synonym: "condensed nuclear chromosome kinetochore-associated DASH complex" EXACT [] +synonym: "Dam1 complex" EXACT [] +synonym: "DDD complex" EXACT [] +synonym: "Duo1p-Dam1p-Dad1p complex" EXACT [] +is_a: GO:0000942 ! condensed nuclear chromosome outer kinetochore + +[Term] +id: GO:0042730 +name: fibrinolysis +namespace: biological_process +def: "A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin." [GOC:jl, PMID:15842654] +xref: Wikipedia:Fibrinolysis +is_a: GO:0030195 ! negative regulation of blood coagulation + +[Term] +id: GO:0042731 +name: PH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton." [GOC:jl, Pfam:PF00169] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0042732 +name: D-xylose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide." [ISBN:0198506732] +synonym: "D-xylose metabolism" EXACT [] +is_a: GO:0019321 ! pentose metabolic process + +[Term] +id: GO:0042733 +name: embryonic digit morphogenesis +namespace: biological_process +def: "The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe." [GOC:bf, GOC:jl, UBERON:0002544] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0030326 ! embryonic limb morphogenesis + +[Term] +id: GO:0042734 +name: presynaptic membrane +namespace: cellular_component +def: "A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane." [GOC:jl, ISBN:0815316194] +subset: goslim_synapse +synonym: "pre-synaptic membrane" EXACT [] +synonym: "presynaptic plasma membrane" EXACT [] +is_a: GO:0097060 ! synaptic membrane +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0042735 +name: protein body +namespace: cellular_component +def: "A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins." [GOC:jl, PMID:7704047] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0042736 +name: NADH kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH." [EC:2.7.1.86, RHEA:12260] +synonym: "ATP:NADH 2'-phosphotransferase activity" EXACT [EC:2.7.1.86] +synonym: "DPNH kinase activity" EXACT [EC:2.7.1.86] +synonym: "reduced diphosphopyridine nucleotide kinase activity" EXACT [EC:2.7.1.86] +synonym: "reduced nicotinamide adenine dinucleotide kinase (phosphorylating)" EXACT [EC:2.7.1.86] +xref: EC:2.7.1.86 +xref: KEGG_REACTION:R00105 +xref: MetaCyc:NADH-KINASE-RXN +xref: RHEA:12260 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0042737 +name: drug catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease." [GOC:go_curators] +synonym: "drug breakdown" EXACT [] +synonym: "drug catabolism" EXACT [] +synonym: "drug degradation" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0042738 +name: exogenous drug catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism." [GOC:jl] +synonym: "exogenous drug breakdown" EXACT [] +synonym: "exogenous drug catabolism" EXACT [] +synonym: "exogenous drug degradation" EXACT [] +is_a: GO:0042737 ! drug catabolic process +relationship: part_of GO:0042493 ! response to drug + +[Term] +id: GO:0042739 +name: endogenous drug catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism." [GOC:jl] +synonym: "endogenous drug breakdown" EXACT [] +synonym: "endogenous drug catabolism" EXACT [] +synonym: "endogenous drug degradation" EXACT [] +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0042740 +name: exogenous antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism." [GOC:jl] +synonym: "exogenous antibiotic breakdown" EXACT [] +synonym: "exogenous antibiotic catabolism" EXACT [] +synonym: "exogenous antibiotic degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042738 ! exogenous drug catabolic process +relationship: part_of GO:0046677 ! response to antibiotic + +[Term] +id: GO:0042741 +name: endogenous antibiotic catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism." [GOC:jl] +synonym: "endogenous antibiotic breakdown" EXACT [] +synonym: "endogenous antibiotic catabolism" EXACT [] +synonym: "endogenous antibiotic degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042739 ! endogenous drug catabolic process + +[Term] +id: GO:0042742 +name: defense response to bacterium +namespace: biological_process +alt_id: GO:0042830 +def: "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl] +synonym: "antibacterial peptide activity" RELATED [] +synonym: "defence response to bacteria" EXACT [] +synonym: "defence response to bacterium" EXACT [] +synonym: "defense response to bacteria" EXACT [] +is_a: GO:0009617 ! response to bacterium +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0042743 +name: hydrogen peroxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA." [GOC:jl, PMID:21734470] +synonym: "H2O2 metabolic process" EXACT [GOC:mah] +synonym: "hydrogen peroxide metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:0072593 ! reactive oxygen species metabolic process + +[Term] +id: GO:0042744 +name: hydrogen peroxide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2)." [GOC:jl] +synonym: "detoxification of H2O2" RELATED [GOC:vw] +synonym: "detoxification of hydrogen peroxide" RELATED [GOC:vw] +synonym: "H2O2 catabolic process" EXACT [GOC:mah] +synonym: "H2O2 scavenging" RELATED [GOC:vw] +synonym: "hydrogen peroxide breakdown" EXACT [] +synonym: "hydrogen peroxide catabolism" EXACT [] +synonym: "hydrogen peroxide degradation" EXACT [] +synonym: "hydrogen peroxide removal" RELATED [] +synonym: "hydrogen peroxide scavenging" RELATED [GOC:vw] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0042743 ! hydrogen peroxide metabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0042745 +name: circadian sleep/wake cycle +namespace: biological_process +def: "The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm." [GOC:jl, http://www.sleepquest.com] +is_a: GO:0048512 ! circadian behavior + +[Term] +id: GO:0042746 +name: circadian sleep/wake cycle, wakefulness +namespace: biological_process +def: "The part of the circadian sleep/wake cycle where the organism is not asleep." [GOC:jl, PMID:12575468] +is_a: GO:0022410 ! circadian sleep/wake cycle process + +[Term] +id: GO:0042747 +name: circadian sleep/wake cycle, REM sleep +namespace: biological_process +def: "A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity." [GOC:jl, ISBN:0395825172] +is_a: GO:0022410 ! circadian sleep/wake cycle process +relationship: part_of GO:0050802 ! circadian sleep/wake cycle, sleep + +[Term] +id: GO:0042748 +name: circadian sleep/wake cycle, non-REM sleep +namespace: biological_process +def: "All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions." [GOC:jl, http://www.sleepquest.com] +is_a: GO:0022410 ! circadian sleep/wake cycle process +relationship: part_of GO:0050802 ! circadian sleep/wake cycle, sleep + +[Term] +id: GO:0042749 +name: regulation of circadian sleep/wake cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle." [GOC:jl] +is_a: GO:0042752 ! regulation of circadian rhythm +is_a: GO:0050795 ! regulation of behavior +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042745 ! circadian sleep/wake cycle +relationship: regulates GO:0042745 ! circadian sleep/wake cycle + +[Term] +id: GO:0042750 +name: hibernation +namespace: biological_process +def: "Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs." [GOC:jl, PMID:1945046] +xref: Wikipedia:Hibernation +is_a: GO:0022611 ! dormancy process +is_a: GO:0030431 ! sleep + +[Term] +id: GO:0042751 +name: estivation +namespace: biological_process +def: "Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season." [GOC:jl, PMID:12443930, Wikipedia:Estivation] +synonym: "aestivation" EXACT [GOC:pr] +xref: Wikipedia:Estivation +is_a: GO:0022611 ! dormancy process +is_a: GO:0030431 ! sleep + +[Term] +id: GO:0042752 +name: regulation of circadian rhythm +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours." [GOC:dph, GOC:jl, GOC:tb] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007623 ! circadian rhythm +relationship: regulates GO:0007623 ! circadian rhythm + +[Term] +id: GO:0042753 +name: positive regulation of circadian rhythm +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior." [GOC:go_curators] +synonym: "activation of circadian rhythm" NARROW [] +synonym: "stimulation of circadian rhythm" NARROW [] +synonym: "up regulation of circadian rhythm" EXACT [] +synonym: "up-regulation of circadian rhythm" EXACT [] +synonym: "upregulation of circadian rhythm" EXACT [] +is_a: GO:0042752 ! regulation of circadian rhythm +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007623 ! circadian rhythm +relationship: positively_regulates GO:0007623 ! circadian rhythm + +[Term] +id: GO:0042754 +name: negative regulation of circadian rhythm +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior." [GOC:go_curators] +synonym: "down regulation of circadian rhythm" EXACT [] +synonym: "down-regulation of circadian rhythm" EXACT [] +synonym: "downregulation of circadian rhythm" EXACT [] +synonym: "inhibition of circadian rhythm" NARROW [] +is_a: GO:0042752 ! regulation of circadian rhythm +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007623 ! circadian rhythm +relationship: negatively_regulates GO:0007623 ! circadian rhythm + +[Term] +id: GO:0042755 +name: eating behavior +namespace: biological_process +def: "The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue." [GOC:jl, GOC:pr, PMID:19361967] +synonym: "eating behaviour" EXACT [] +is_a: GO:0007631 ! feeding behavior + +[Term] +id: GO:0042756 +name: drinking behavior +namespace: biological_process +def: "The specific behavior of an organism relating to the intake of liquids, especially water." [GOC:curators, GOC:pr] +synonym: "drinking behaviour" EXACT [] +is_a: GO:0007631 ! feeding behavior + +[Term] +id: GO:0042757 +name: giant axon +namespace: cellular_component +def: "Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses." [GOC:jl, PMID:9705477] +is_a: GO:0030424 ! axon + +[Term] +id: GO:0042758 +name: long-chain fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22." [PMID:20043225] +synonym: "long-chain fatty acid breakdown" EXACT [] +synonym: "long-chain fatty acid catabolism" EXACT [] +synonym: "long-chain fatty acid degradation" EXACT [] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0009062 ! fatty acid catabolic process + +[Term] +id: GO:0042759 +name: long-chain fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22." [PMID:18390550] +synonym: "long-chain fatty acid anabolism" EXACT [] +synonym: "long-chain fatty acid biosynthesis" EXACT [] +synonym: "long-chain fatty acid formation" EXACT [] +synonym: "long-chain fatty acid synthesis" EXACT [] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0042760 +name: very long-chain fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22." [PMID:7744868] +synonym: "very-long-chain fatty acid breakdown" EXACT [] +synonym: "very-long-chain fatty acid catabolic process" EXACT [] +synonym: "very-long-chain fatty acid catabolism" EXACT [] +synonym: "very-long-chain fatty acid degradation" EXACT [] +is_a: GO:0000038 ! very long-chain fatty acid metabolic process +is_a: GO:0009062 ! fatty acid catabolic process + +[Term] +id: GO:0042761 +name: very long-chain fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22." [PMID:7744868] +synonym: "very-long-chain fatty acid anabolism" EXACT [] +synonym: "very-long-chain fatty acid biosynthesis" EXACT [] +synonym: "very-long-chain fatty acid biosynthetic process" EXACT [] +synonym: "very-long-chain fatty acid formation" EXACT [] +synonym: "very-long-chain fatty acid synthesis" EXACT [] +xref: MetaCyc:PWY-5080 +is_a: GO:0000038 ! very long-chain fatty acid metabolic process +is_a: GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0042762 +name: regulation of sulfur metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] +synonym: "regulation of sulfur metabolism" EXACT [] +synonym: "regulation of sulphur metabolic process" EXACT [] +synonym: "regulation of sulphur metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006790 ! sulfur compound metabolic process +relationship: regulates GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0042763 +name: intracellular immature spore +namespace: cellular_component +def: "A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants." [GOC:jl, ISBN:0395825172] +synonym: "forespore" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0042764 +name: ascospore-type prospore +namespace: cellular_component +def: "An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi." [GOC:go_curators] +is_a: GO:0042763 ! intracellular immature spore + +[Term] +id: GO:0042765 +name: GPI-anchor transamidase complex +namespace: cellular_component +def: "An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor." [GOC:jl, GOC:rb, PMID:12802054] +comment: Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity. +synonym: "GPIT complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0030176 ! integral component of endoplasmic reticulum membrane + +[Term] +id: GO:0042766 +name: nucleosome mobilization +namespace: biological_process +def: "The movement of nucleosomes along a DNA fragment." [PMID:12006495] +synonym: "nucleosome sliding" EXACT [GOC:dph] +is_a: GO:0006338 ! chromatin remodeling +is_a: GO:0034728 ! nucleosome organization + +[Term] +id: GO:0042767 +name: ecdysteroid 22-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 22." [PMID:12177427] +comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22-dideoxyecdysone (ketotriol) to 2-deoxyecdysone. +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0042768 +name: ecdysteroid 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 2." [PMID:12177427] +comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2-deoxyecdysone to ecdysone. It can also catalyze the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone. +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0042769 +name: DNA damage response, detection of DNA damage +namespace: biological_process +def: "The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal." [GOC:go_curators] +synonym: "detection of DNA damage during DNA damage response" EXACT [] +synonym: "DNA damage response, perception of DNA damage" RELATED [] +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0051606 ! detection of stimulus + +[Term] +id: GO:0042770 +name: signal transduction in response to DNA damage +namespace: biological_process +def: "A cascade of processes induced by the detection of DNA damage within a cell." [GOC:go_curators] +synonym: "DNA damage response, signal transduction" EXACT [] +synonym: "response to DNA damage stimulus by intracellular signaling cascade" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0042771 +name: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [] +is_a: GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator + +[Term] +id: GO:0042772 +name: DNA damage response, signal transduction resulting in transcription +namespace: biological_process +def: "A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription." [GOC:go_curators] +is_a: GO:0042770 ! signal transduction in response to DNA damage + +[Term] +id: GO:0042773 +name: ATP synthesis coupled electron transport +namespace: biological_process +def: "The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP." [ISBN:0716731363] +is_a: GO:0022904 ! respiratory electron transport chain +relationship: part_of GO:0006119 ! oxidative phosphorylation + +[Term] +id: GO:0042774 +name: plasma membrane ATP synthesis coupled electron transport +namespace: biological_process +def: "The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane." [GOC:mtg_sensu, ISBN:0716731363] +is_a: GO:0042773 ! ATP synthesis coupled electron transport +intersection_of: GO:0042773 ! ATP synthesis coupled electron transport +intersection_of: occurs_in GO:0005886 ! plasma membrane +relationship: occurs_in GO:0005886 ! plasma membrane + +[Term] +id: GO:0042775 +name: mitochondrial ATP synthesis coupled electron transport +namespace: biological_process +def: "The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane." [GOC:mtg_sensu, ISBN:0716731363] +synonym: "mitochondrial electron transport" BROAD [] +synonym: "organelle ATP synthesis coupled electron transport" BROAD [] +is_a: GO:0042773 ! ATP synthesis coupled electron transport +intersection_of: GO:0042773 ! ATP synthesis coupled electron transport +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0042776 +name: mitochondrial ATP synthesis coupled proton transport +namespace: biological_process +def: "The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis." [GOC:mtg_sensu, ISBN:0716731363] +synonym: "mitochondrial proton transport" BROAD [] +is_a: GO:0006119 ! oxidative phosphorylation +is_a: GO:0015986 ! ATP synthesis coupled proton transport +is_a: GO:0046907 ! intracellular transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +intersection_of: GO:0015986 ! ATP synthesis coupled proton transport +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0042777 +name: plasma membrane ATP synthesis coupled proton transport +namespace: biological_process +def: "The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis." [GOC:mtg_sensu, ISBN:0716731363] +synonym: "ATP synthesis coupled proton transport" BROAD [] +is_a: GO:0015986 ! ATP synthesis coupled proton transport + +[Term] +id: GO:0042778 +name: tRNA end turnover +namespace: biological_process +def: "The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA." [GOC:go_curators] +is_a: GO:0006399 ! tRNA metabolic process + +[Term] +id: GO:0042779 +name: tRNA 3'-trailer cleavage +namespace: biological_process +def: "Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both." [GOC:go_curators] +synonym: "removal of tRNA 3'-trailer sequence" EXACT [] +synonym: "tRNA 3'-end cleavage" EXACT [] +is_a: GO:0090501 ! RNA phosphodiester bond hydrolysis +relationship: part_of GO:0042780 ! tRNA 3'-end processing + +[Term] +id: GO:0042780 +name: tRNA 3'-end processing +namespace: biological_process +def: "The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA." [GOC:go_curators] +synonym: "tRNA 3' processing" EXACT [] +is_a: GO:0008033 ! tRNA processing +is_a: GO:0043628 ! ncRNA 3'-end processing + +[Term] +id: GO:0042781 +name: 3'-tRNA processing endoribonuclease activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule." [EC:3.1.26.11] +synonym: "3 tRNase activity" EXACT [EC:3.1.26.11] +synonym: "3' tRNA processing endoribonuclease activity" EXACT [] +synonym: "3' tRNase activity" EXACT [] +synonym: "ribonuclease Z activity" BROAD [] +synonym: "RNase Z activity" BROAD [] +synonym: "tRNA 3 endonuclease activity" EXACT [EC:3.1.26.11] +synonym: "tRNA 3' endonuclease activity" EXACT [] +synonym: "tRNAse Z" RELATED [EC:3.1.26.11] +xref: MetaCyc:3.1.26.11-RXN +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters +relationship: part_of GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic + +[Term] +id: GO:0042783 +name: evasion of host immune response +namespace: biological_process +alt_id: GO:0020012 +alt_id: GO:0042782 +alt_id: GO:0051805 +alt_id: GO:0051809 +alt_id: GO:0051810 +def: "A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mb, PMID:12439615] +synonym: "active evasion of host immune response" RELATED [] +synonym: "active evasion of immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "active immune evasion" BROAD [] +synonym: "evasion or tolerance of host immune response" BROAD [] +synonym: "immune evasion" EXACT [] +synonym: "mitigation of host immune response" RELATED [] +synonym: "passive evasion of host immune response" RELATED [] +synonym: "passive evasion of immune response of other organism involved in symbiotic interaction" RELATED [] +synonym: "passive immune evasion" RELATED [] +is_a: GO:0052572 ! response to host immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17894 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18357 xsd:anyURI + +[Term] +id: GO:0042784 +name: evasion of host immune response via regulation of host complement system +namespace: biological_process +alt_id: GO:0051811 +def: "Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction." [http://www.brown.edu/Courses/Bio_160/Projects1999/ies/ces.html] +synonym: "active evasion of host immune response via regulation of host complement system" RELATED [] +synonym: "active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction" BROAD [] +synonym: "active immune evasion via modulation of host complement system" EXACT [] +synonym: "active immune evasion via regulation of host complement system" EXACT [] +is_a: GO:0042783 ! evasion of host immune response + +[Term] +id: GO:0042785 +name: evasion of host immune response via regulation of host cytokine network +namespace: biological_process +alt_id: GO:0051812 +def: "Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction." [http://www.brown.edu/Courses/Bio_160/Projects1999/ies/cytok.html#Manipulation] +synonym: "active evasion of host immune response via regulation of host cytokine network" RELATED [] +synonym: "active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction" BROAD [] +synonym: "active immune evasion via modulation of host cytokine network" EXACT [] +synonym: "active immune evasion via regulation of host cytokine network" EXACT [] +is_a: GO:0042783 ! evasion of host immune response + +[Term] +id: GO:0042786 +name: evasion of host immune response via regulation of host antigen processing and presentation +namespace: biological_process +alt_id: GO:0051813 +def: "Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:12439615] +synonym: "active evasion of host immune response via regulation of host antigen processing and presentation" RELATED [] +synonym: "active evasion of host immune response via regulation of host antigen processing and presentation pathway" EXACT [] +synonym: "active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction" BROAD [] +synonym: "active immune evasion via modulation of antigen processing and presentation" EXACT [] +synonym: "active immune evasion via modulation of antigen processing/presentation" EXACT [] +synonym: "active immune evasion via regulation of antigen processing and presentation" EXACT [] +is_a: GO:0042783 ! evasion of host immune response + +[Term] +id: GO:0042788 +name: polysomal ribosome +namespace: cellular_component +def: "A ribosome bound to mRNA that forms part of a polysome." [GOC:jl] +synonym: "active ribosome" BROAD [] +is_a: GO:0005840 ! ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0005844 ! polysome +relationship: part_of GO:0005844 ! polysome + +[Term] +id: GO:0042789 +name: mRNA transcription by RNA polymerase II +namespace: biological_process +def: "The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter." [GOC:jl, ISBN:0321000382] +synonym: "mRNA transcription from Pol II promoter" EXACT [] +synonym: "mRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:0009299 ! mRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042790 +name: nucleolar large rRNA transcription by RNA polymerase I +namespace: biological_process +def: "The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I." [GOC:jl, GOC:txnOH, ISBN:0321000382] +synonym: "transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [] +synonym: "transcription of nuclear rRNA large Pol I transcript" EXACT [] +synonym: "transcription of nucleolar large rRNA by RNA polymerase I" EXACT [] +is_a: GO:0006360 ! transcription by RNA polymerase I +is_a: GO:0009303 ! rRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042791 +name: 5S class rRNA transcription by RNA polymerase III +namespace: biological_process +def: "The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter." [GOC:jl, GOC:txnOH, ISBN:0321000382, PMID:12381659] +synonym: "5S class rRNA transcription from RNA polymerase III type 1 promoter" RELATED [] +synonym: "5S rRNA transcription" EXACT [] +is_a: GO:0006383 ! transcription by RNA polymerase III +is_a: GO:0009303 ! rRNA transcription + +[Term] +id: GO:0042792 +name: mitochondrial rRNA transcription +namespace: biological_process +def: "The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template." [GOC:jl, ISBN:0321000382] +synonym: "rRNA transcription from mitochondrial promoter" EXACT [] +is_a: GO:0006390 ! mitochondrial transcription +is_a: GO:0009303 ! rRNA transcription + +[Term] +id: GO:0042793 +name: plastid transcription +namespace: biological_process +def: "The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase." [GOC:jl, ISBN:0321000382] +synonym: "transcription from plastid promoter" EXACT [] +is_a: GO:0006351 ! transcription, DNA-templated +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042794 +name: plastid rRNA transcription +namespace: biological_process +def: "The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase." [GOC:jl, ISBN:0321000382] +synonym: "rRNA transcription from plastid promoter" EXACT [] +is_a: GO:0009303 ! rRNA transcription +is_a: GO:0042793 ! plastid transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042795 +name: snRNA transcription by RNA polymerase II +namespace: biological_process +def: "The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter." [GOC:jl, ISBN:0321000382] +synonym: "snRNA transcription from Pol II promoter" EXACT [] +synonym: "snRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:0009301 ! snRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042796 +name: snRNA transcription by RNA polymerase III +namespace: biological_process +def: "The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter." [GOC:jl, ISBN:0321000382] +synonym: "snRNA transcription from Pol III promoter" EXACT [] +synonym: "snRNA transcription from RNA polymerase III promoter" EXACT [] +is_a: GO:0006383 ! transcription by RNA polymerase III +is_a: GO:0009301 ! snRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042797 +name: tRNA transcription by RNA polymerase III +namespace: biological_process +def: "The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter." [GOC:jl, ISBN:0321000382] +synonym: "tRNA transcription from Pol III promoter" EXACT [] +synonym: "tRNA transcription from RNA polymerase III promoter" EXACT [] +is_a: GO:0006383 ! transcription by RNA polymerase III +is_a: GO:0009304 ! tRNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI + +[Term] +id: GO:0042798 +name: obsolete protein neddylation during NEDD8 class-dependent protein catabolic process +namespace: biological_process +def: "OBSOLETE. Covalent attachment of the ubiquitin-like protein NEDD8 (or equivalent protein) to another protein, as a part of NEDD8-dependant protein catabolism." [GOC:jl] +comment: This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction. +synonym: "protein neddylation during NEDD8 class-dependent protein breakdown" EXACT [] +synonym: "protein neddylation during NEDD8 class-dependent protein catabolic process" EXACT [] +synonym: "protein neddylation during NEDD8 class-dependent protein catabolism" EXACT [] +synonym: "protein neddylation during NEDD8 class-dependent protein degradation" EXACT [] +synonym: "protein neddylation during RUB1-dependent protein catabolic process" EXACT [] +synonym: "protein neddylation during RUB1-dependent protein catabolism" EXACT [] +is_obsolete: true +consider: GO:0045116 + +[Term] +id: GO:0042799 +name: histone methyltransferase activity (H4-K20 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein." [PMID:12086618] +comment: Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies. +synonym: "histone H4 lysine 20-specific methyltransferase activity" EXACT [] +synonym: "histone lysine N-methyltransferase activity (H4-K20 specific)" EXACT [] +synonym: "histone methylase activity (H4-K20 specific)" EXACT [GOC:mah] +xref: Reactome:R-HSA-2301205 "SETD8 monomethylates histone H4" +xref: Reactome:R-HSA-5682965 "WHSC1 dimethylates histone H4 on lysine K21 at DSBs" +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0042800 +name: histone methyltransferase activity (H3-K4 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein." [PMID:12086618] +comment: Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies. +synonym: "histone H3 lysine 4-specific methyltransferase activity" EXACT [] +synonym: "histone lysine N-methyltransferase activity (H3-K4 specific)" EXACT [] +synonym: "histone methylase activity (H3-K4 specific)" EXACT [GOC:mah] +xref: Reactome:R-HSA-1214188 "PRDM9 trimethylates histone H3" +xref: Reactome:R-HSA-3364026 "SET1 complex trimethylates H3K4 at the MYC gene" +xref: Reactome:R-HSA-8865498 "KMT2A trimethylates nucleosomes at the SPI1 gene locus producing H3K4Me3 mark" +xref: Reactome:R-HSA-8936481 "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter" +xref: Reactome:R-HSA-8936621 "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter" +xref: Reactome:R-HSA-8937016 "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter" +xref: Reactome:R-HSA-8937050 "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter" +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0051568 ! histone H3-K4 methylation + +[Term] +id: GO:0042801 +name: obsolete polo kinase kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins." [GOC:ma] +comment: This term was made obsolete because it represents a gene product and also refers to a non-existent activity (polo kinase). +is_obsolete: true + +[Term] +id: GO:0042802 +name: identical protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an identical protein or proteins." [GOC:jl] +subset: goslim_chembl +synonym: "isoform-specific homophilic binding" EXACT [PMID:17889655] +synonym: "protein homopolymerization" RELATED [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0042803 +name: protein homodimerization activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with an identical protein to form a homodimer." [GOC:jl] +subset: goslim_chembl +synonym: "dimerization activity" BROAD [] +is_a: GO:0042802 ! identical protein binding +is_a: GO:0046983 ! protein dimerization activity + +[Term] +id: GO:0042804 +name: obsolete protein homooligomerization activity +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with identical proteins to form a homooligomer." [GOC:jl] +comment: This term was made obsolete because it represents a biological process. +synonym: "oligomerization activity" BROAD [] +synonym: "protein homooligomerization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051260 + +[Term] +id: GO:0042805 +name: actinin binding +namespace: molecular_function +alt_id: GO:0051406 +def: "Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin." [GOC:jl, ISBN:0198506732] +synonym: "beta-actinin binding" NARROW [] +synonym: "capZ binding" EXACT [] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0042806 +name: fucose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with fucose, the pentose 6-deoxygalactose." [ISBN:0582227089] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0042807 +name: central vacuole +namespace: cellular_component +def: "A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination." [ISBN:9780815341116, Wikipedia:Vacuole] +is_a: GO:0000325 ! plant-type vacuole + +[Term] +id: GO:0042808 +name: obsolete neuronal Cdc2-like kinase binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics." [GOC:jl, PMID:10721722] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "neuronal Cdc2-like kinase binding" EXACT [] +is_obsolete: true +replaced_by: GO:0019901 + +[Term] +id: GO:0042809 +name: vitamin D receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes." [GOC:jl, PMID:12637589] +synonym: "calciferol receptor binding" NARROW [] +synonym: "VDR binding" EXACT [] +is_a: GO:0035257 ! nuclear hormone receptor binding + +[Term] +id: GO:0042810 +name: pheromone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." [ISBN:0198506732] +subset: goslim_pir +synonym: "pheromone metabolism" EXACT [] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0042811 +name: pheromone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." [ISBN:0198506732] +synonym: "pheromone anabolism" EXACT [] +synonym: "pheromone biosynthesis" EXACT [] +synonym: "pheromone formation" EXACT [] +synonym: "pheromone synthesis" EXACT [] +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0042810 ! pheromone metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process + +[Term] +id: GO:0042812 +name: pheromone catabolic process +namespace: biological_process +alt_id: GO:0007327 +alt_id: GO:0046614 +def: "The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." [ISBN:0198506732] +synonym: "pheromone breakdown" EXACT [] +synonym: "pheromone catabolism" EXACT [] +synonym: "pheromone degradation" EXACT [] +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042810 ! pheromone metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0042813 +name: Wnt-activated receptor activity +namespace: molecular_function +def: "Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:go_curators] +subset: goslim_chembl +synonym: "frizzled receptor activity" RELATED [] +synonym: "frizzled-2 receptor activity" RELATED [] +synonym: "Wnt receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004888 ! transmembrane signaling receptor activity +relationship: has_part GO:0017147 ! Wnt-protein binding +relationship: part_of GO:0016055 ! Wnt signaling pathway + +[Term] +id: GO:0042814 +name: monopolar cell growth +namespace: biological_process +def: "Polarized growth from one end of a cell." [GOC:vw] +synonym: "monopolar cell elongation" NARROW [] +synonym: "monopolar growth" BROAD [] +synonym: "polar cell elongation" NARROW [] +is_a: GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0042815 +name: bipolar cell growth +namespace: biological_process +def: "The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell." [GOC:vw] +comment: Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term 'establishment or maintenance of bipolar cell polarity resulting in cell shape ; GO:0061246' and its children. +synonym: "bipolar cell elongation" NARROW [] +synonym: "bipolar growth" BROAD [] +synonym: "polar cell elongation" RELATED [] +is_a: GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0042816 +name: vitamin B6 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "vitamin B6 metabolism" EXACT [] +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process + +[Term] +id: GO:0042817 +name: pyridoxal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:jl, http://www.mblab.gla.ac.uk/] +synonym: "pyridoxal metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042818 +name: pyridoxamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:jl] +synonym: "pyridoxamine metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042819 +name: vitamin B6 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "pyridoxine-5'-phosphate biosynthesis" RELATED [GOC:yaf, UniPathway:UPA00244] +synonym: "vitamin B6 anabolism" EXACT [] +synonym: "vitamin B6 biosynthesis" EXACT [] +synonym: "vitamin B6 formation" EXACT [] +synonym: "vitamin B6 synthesis" EXACT [] +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process + +[Term] +id: GO:0042820 +name: vitamin B6 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html] +synonym: "vitamin B6 breakdown" EXACT [] +synonym: "vitamin B6 catabolism" EXACT [] +synonym: "vitamin B6 degradation" EXACT [] +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process + +[Term] +id: GO:0042821 +name: pyridoxal biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds." [GOC:jl, http://www.mblab.gla.ac.uk/] +synonym: "pyridoxal anabolism" EXACT [] +synonym: "pyridoxal biosynthesis" EXACT [] +synonym: "pyridoxal formation" EXACT [] +synonym: "pyridoxal synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042817 ! pyridoxal metabolic process +is_a: GO:0042819 ! vitamin B6 biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0042822 +name: pyridoxal phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6." [GOC:jl, http://www.mercksource.com/] +synonym: "active vitamin B6 metabolic process" EXACT [] +synonym: "active vitamin B6 metabolism" EXACT [] +synonym: "pyridoxal phosphate metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0042816 ! vitamin B6 metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042823 +name: pyridoxal phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6." [GOC:jl, http://www.mercksource.com/] +synonym: "active vitamin B6 biosynthesis" EXACT [] +synonym: "active vitamin B6 biosynthetic process" EXACT [] +synonym: "pyridoxal phosphate anabolism" EXACT [] +synonym: "pyridoxal phosphate biosynthesis" EXACT [] +synonym: "pyridoxal phosphate formation" EXACT [] +synonym: "pyridoxal phosphate synthesis" EXACT [] +xref: MetaCyc:PWY0-845 +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042819 ! vitamin B6 biosynthetic process +is_a: GO:0042822 ! pyridoxal phosphate metabolic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0042824 +name: MHC class I peptide loading complex +namespace: cellular_component +def: "A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules." [GOC:jl, PMID:10631934] +comment: Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi. +subset: goslim_pir +synonym: "peptide-loading complex" EXACT [GOC:bhm] +synonym: "PLC" RELATED [GOC:bhm] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0030176 ! integral component of endoplasmic reticulum membrane + +[Term] +id: GO:0042825 +name: TAP complex +namespace: cellular_component +def: "A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum." [GOC:jl, PMID:10618487, PMID:10631934] +synonym: "transporter associated with antigen presentation" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0042824 ! MHC class I peptide loading complex + +[Term] +id: GO:0042826 +name: histone deacetylase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme histone deacetylase." [GOC:jl] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0042827 +name: platelet dense granule +namespace: cellular_component +def: "Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins." [GOC:jl, http://www.mercksource.com/, PMID:10403682, PMID:11487378] +synonym: "bull's eye body" EXACT [] +synonym: "platelet dense body" EXACT [] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0042832 +name: defense response to protozoan +namespace: biological_process +def: "Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism." [GOC:jl] +synonym: "defence response to pathogenic protozoa" EXACT [] +synonym: "defence response to protozoa" EXACT [] +synonym: "defence response to protozoon" EXACT [] +synonym: "defense response to pathogenic protozoa" EXACT [] +synonym: "defense response to protozoa" EXACT [] +synonym: "defense response to protozoon" EXACT [] +is_a: GO:0001562 ! response to protozoan +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0042834 +name: peptidoglycan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls." [GOC:go_curators, PMID:14698226] +is_a: GO:0005539 ! glycosaminoglycan binding + +[Term] +id: GO:0042835 +name: BRE binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the RNA element BRE (Bruno response element)." [PMID:10893231] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0042836 +name: D-glucarate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-glucarate metabolism" EXACT [] +synonym: "saccharate metabolic process" EXACT [] +synonym: "saccharate metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019392 ! glucarate metabolic process + +[Term] +id: GO:0042837 +name: D-glucarate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-glucarate anabolism" EXACT [] +synonym: "D-glucarate biosynthesis" EXACT [] +synonym: "D-glucarate formation" EXACT [] +synonym: "D-glucarate synthesis" EXACT [] +synonym: "saccharate biosynthesis" EXACT [] +synonym: "saccharate biosynthetic process" EXACT [] +is_a: GO:0019393 ! glucarate biosynthetic process +is_a: GO:0042836 ! D-glucarate metabolic process + +[Term] +id: GO:0042838 +name: D-glucarate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-glucarate breakdown" EXACT [] +synonym: "D-glucarate catabolism" EXACT [] +synonym: "D-glucarate degradation" EXACT [] +synonym: "saccharate catabolic process" EXACT [] +synonym: "saccharate catabolism" EXACT [] +is_a: GO:0019394 ! glucarate catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0042836 ! D-glucarate metabolic process + +[Term] +id: GO:0042839 +name: D-glucuronate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "D-glucuronate metabolism" EXACT [] +is_a: GO:0019585 ! glucuronate metabolic process + +[Term] +id: GO:0042840 +name: D-glucuronate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "D-glucuronate breakdown" EXACT [] +synonym: "D-glucuronate catabolism" EXACT [] +synonym: "D-glucuronate degradation" EXACT [] +is_a: GO:0006064 ! glucuronate catabolic process +is_a: GO:0042839 ! D-glucuronate metabolic process + +[Term] +id: GO:0042841 +name: D-glucuronate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "D-glucuronate anabolism" EXACT [] +synonym: "D-glucuronate biosynthesis" EXACT [] +synonym: "D-glucuronate formation" EXACT [] +synonym: "D-glucuronate synthesis" EXACT [] +is_a: GO:0042839 ! D-glucuronate metabolic process +is_a: GO:0046399 ! glucuronate biosynthetic process + +[Term] +id: GO:0042842 +name: D-xylose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide." [ISBN:0198506732] +synonym: "D-xylose anabolism" EXACT [] +synonym: "D-xylose biosynthesis" EXACT [] +synonym: "D-xylose formation" EXACT [] +synonym: "D-xylose synthesis" EXACT [] +is_a: GO:0019322 ! pentose biosynthetic process +is_a: GO:0042732 ! D-xylose metabolic process + +[Term] +id: GO:0042843 +name: D-xylose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide." [ISBN:0198506732] +synonym: "D-xylose breakdown" EXACT [] +synonym: "D-xylose catabolism" EXACT [] +synonym: "D-xylose degradation" EXACT [] +is_a: GO:0019323 ! pentose catabolic process +is_a: GO:0042732 ! D-xylose metabolic process + +[Term] +id: GO:0042844 +name: glycol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." [PMID:9851711] +synonym: "dihydric alcohol metabolic process" BROAD [] +synonym: "dihydric alcohol metabolism" BROAD [] +synonym: "glycol metabolism" EXACT [] +is_a: GO:0034311 ! diol metabolic process + +[Term] +id: GO:0042845 +name: glycol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." [GOC:curators] +synonym: "dihydric alcohol biosynthesis" BROAD [] +synonym: "dihydric alcohol biosynthetic process" BROAD [] +synonym: "glycol anabolism" EXACT [] +synonym: "glycol biosynthesis" EXACT [] +synonym: "glycol formation" EXACT [] +synonym: "glycol synthesis" EXACT [] +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0042844 ! glycol metabolic process + +[Term] +id: GO:0042846 +name: glycol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." [Wikipedia:Ethylene_glycol] +synonym: "dihydric alcohol catabolic process" BROAD [] +synonym: "dihydric alcohol catabolism" BROAD [] +synonym: "glycol breakdown" EXACT [] +synonym: "glycol catabolism" EXACT [] +synonym: "glycol degradation" EXACT [] +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0042844 ! glycol metabolic process + +[Term] +id: GO:0042847 +name: sorbose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid." [ISBN:0198506732] +synonym: "sorbose anabolism" EXACT [] +synonym: "sorbose biosynthesis" EXACT [] +synonym: "sorbose formation" EXACT [] +synonym: "sorbose synthesis" EXACT [] +is_a: GO:0019311 ! sorbose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0042848 +name: sorbose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid." [ISBN:0198506732] +synonym: "sorbose breakdown" EXACT [] +synonym: "sorbose catabolism" EXACT [] +synonym: "sorbose degradation" EXACT [] +is_a: GO:0019311 ! sorbose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0042849 +name: L-sorbose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol." [ISBN:0198506732] +synonym: "L-sorbose anabolism" EXACT [] +synonym: "L-sorbose biosynthesis" EXACT [] +synonym: "L-sorbose formation" EXACT [] +synonym: "L-sorbose synthesis" EXACT [] +is_a: GO:0019312 ! L-sorbose metabolic process +is_a: GO:0042847 ! sorbose biosynthetic process + +[Term] +id: GO:0042850 +name: L-sorbose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-sorbose breakdown" EXACT [] +synonym: "L-sorbose catabolism" EXACT [] +synonym: "L-sorbose degradation" EXACT [] +is_a: GO:0019312 ! L-sorbose metabolic process +is_a: GO:0042848 ! sorbose catabolic process + +[Term] +id: GO:0042851 +name: L-alanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "L-alanine metabolism" EXACT [] +is_a: GO:0006522 ! alanine metabolic process + +[Term] +id: GO:0042852 +name: L-alanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "L-alanine anabolism" EXACT [] +synonym: "L-alanine biosynthesis" EXACT [] +synonym: "L-alanine formation" EXACT [] +synonym: "L-alanine synthesis" EXACT [] +is_a: GO:0006523 ! alanine biosynthetic process +is_a: GO:0042851 ! L-alanine metabolic process + +[Term] +id: GO:0042853 +name: L-alanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "L-alanine breakdown" EXACT [] +synonym: "L-alanine catabolism" EXACT [] +synonym: "L-alanine degradation" EXACT [] +is_a: GO:0006524 ! alanine catabolic process +is_a: GO:0042851 ! L-alanine metabolic process + +[Term] +id: GO:0042854 +name: eugenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil." [GOC:jl] +synonym: "4-allyl-2-methoxyphenol metabolic process" EXACT [] +synonym: "4-allyl-2-methoxyphenol metabolism" EXACT [] +synonym: "eugenic acid metabolic process" EXACT [] +synonym: "eugenic acid metabolism" EXACT [] +synonym: "eugenol metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0042855 +name: eugenol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil." [GOC:jl] +synonym: "4-allyl-2-methoxyphenol biosynthesis" EXACT [] +synonym: "4-allyl-2-methoxyphenol biosynthetic process" EXACT [] +synonym: "eugenic acid biosynthesis" EXACT [] +synonym: "eugenic acid biosynthetic process" EXACT [] +synonym: "eugenol anabolism" EXACT [] +synonym: "eugenol biosynthesis" EXACT [] +synonym: "eugenol formation" EXACT [] +synonym: "eugenol synthesis" EXACT [] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0042854 ! eugenol metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0042856 +name: eugenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil." [GOC:jl] +synonym: "4-allyl-2-methoxyphenol catabolic process" EXACT [] +synonym: "4-allyl-2-methoxyphenol catabolism" EXACT [] +synonym: "eugenic acid catabolic process" EXACT [] +synonym: "eugenic acid catabolism" EXACT [] +synonym: "eugenol breakdown" EXACT [] +synonym: "eugenol catabolism" EXACT [] +synonym: "eugenol degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042854 ! eugenol metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0042857 +name: chrysobactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)." [GOC:jl, PMID:8837459] +synonym: "chrysobactin metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0042858 +name: chrysobactin biosynthetic process +namespace: biological_process +alt_id: GO:0031183 +alt_id: GO:0031184 +def: "The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)." [GOC:jl, PMID:8837459] +synonym: "chrysobactin anabolism" EXACT [] +synonym: "chrysobactin biosynthesis" EXACT [] +synonym: "chrysobactin biosynthetic process, peptide formation" NARROW [] +synonym: "chrysobactin biosynthetic process, peptide modification" NARROW [] +synonym: "chrysobactin formation" EXACT [] +synonym: "chrysobactin synthesis" EXACT [] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0019290 ! siderophore biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0042857 ! chrysobactin metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901162 ! primary amino compound biosynthetic process + +[Term] +id: GO:0042859 +name: chrysobactin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)." [GOC:jl, PMID:8837459] +synonym: "chrysobactin breakdown" EXACT [] +synonym: "chrysobactin catabolism" EXACT [] +synonym: "chrysobactin degradation" EXACT [] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0042857 ! chrysobactin metabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0046215 ! siderophore catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901161 ! primary amino compound catabolic process + +[Term] +id: GO:0042860 +name: achromobactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving achromobactin, a citrate siderophore." [GOC:jl, PMID:10928541] +synonym: "achromobactin metabolism" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0042861 +name: achromobactin biosynthetic process +namespace: biological_process +alt_id: GO:0031181 +alt_id: GO:0031182 +def: "The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore." [GOC:jl, PMID:10928541] +synonym: "achromobactin anabolism" EXACT [] +synonym: "achromobactin biosynthesis" EXACT [] +synonym: "achromobactin biosynthetic process, peptide formation" NARROW [] +synonym: "achromobactin biosynthetic process, peptide modification" NARROW [] +synonym: "achromobactin formation" EXACT [] +synonym: "achromobactin synthesis" EXACT [] +is_a: GO:0019290 ! siderophore biosynthetic process +is_a: GO:0042860 ! achromobactin metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0042862 +name: achromobactin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore." [GOC:jl, PMID:10928541] +synonym: "achromobactin breakdown" EXACT [] +synonym: "achromobactin catabolism" EXACT [] +synonym: "achromobactin degradation" EXACT [] +is_a: GO:0042860 ! achromobactin metabolic process +is_a: GO:0046215 ! siderophore catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0042863 +name: pyochelin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)." [GOC:jl, PMID:6794030] +synonym: "pyochelin metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0042864 +name: pyochelin biosynthetic process +namespace: biological_process +alt_id: GO:0031187 +alt_id: GO:0031188 +def: "The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)." [GOC:jl, PMID:6794030] +synonym: "pyochelin anabolism" EXACT [] +synonym: "pyochelin biosynthesis" EXACT [] +synonym: "pyochelin biosynthetic process, peptide formation" NARROW [] +synonym: "pyochelin biosynthetic process, peptide modification" NARROW [] +synonym: "pyochelin formation" EXACT [] +synonym: "pyochelin synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019290 ! siderophore biosynthetic process +is_a: GO:0042863 ! pyochelin metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0042865 +name: pyochelin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)." [GOC:jl, PMID:6794030] +synonym: "pyochelin breakdown" EXACT [] +synonym: "pyochelin catabolism" EXACT [] +synonym: "pyochelin degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042863 ! pyochelin metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046215 ! siderophore catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0042866 +name: pyruvate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate." [GOC:go_curators] +synonym: "pyruvate anabolism" EXACT [] +synonym: "pyruvate biosynthesis" EXACT [] +synonym: "pyruvate formation" EXACT [] +synonym: "pyruvate synthesis" EXACT [] +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0042867 +name: pyruvate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate." [GOC:go_curators] +synonym: "pyruvate breakdown" EXACT [] +synonym: "pyruvate catabolism" EXACT [] +synonym: "pyruvate degradation" EXACT [] +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0042868 +name: antisense RNA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis." [GOC:jl] +synonym: "antisense RNA metabolism" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process + +[Term] +id: GO:0042869 +name: aldarate transmembrane transport +namespace: biological_process +def: "The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:go_curators] +synonym: "aldarate transport" RELATED [] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0034219 ! carbohydrate transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0042870 +name: D-glucarate transmembrane transport +namespace: biological_process +def: "The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-glucarate transport" RELATED [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0042869 ! aldarate transmembrane transport + +[Term] +id: GO:0042873 +name: aldonate transmembrane transport +namespace: biological_process +def: "The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl] +synonym: "aldonate transport" RELATED [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0034219 ! carbohydrate transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0042874 +name: D-glucuronate transmembrane transport +namespace: biological_process +def: "The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "D-glucuronate transport" RELATED [] +is_a: GO:0015738 ! glucuronate transmembrane transport + +[Term] +id: GO:0042875 +name: D-galactonate transmembrane transport +namespace: biological_process +def: "The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah] +synonym: "D-galactonate transport" RELATED [] +is_a: GO:0042873 ! aldonate transmembrane transport + +[Term] +id: GO:0042876 +name: aldarate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of aldarate from one side of a membrane to the other." [GOC:go_curators, PMID:15034926] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +relationship: part_of GO:0042869 ! aldarate transmembrane transport + +[Term] +id: GO:0042878 +name: D-glucarate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0042876 ! aldarate transmembrane transporter activity +relationship: part_of GO:0042870 ! D-glucarate transmembrane transport + +[Term] +id: GO:0042879 +name: aldonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of aldonate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +relationship: part_of GO:0042873 ! aldonate transmembrane transport + +[Term] +id: GO:0042880 +name: D-glucuronate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0015135 ! glucuronate transmembrane transporter activity +relationship: part_of GO:0042874 ! D-glucuronate transmembrane transport + +[Term] +id: GO:0042881 +name: D-galactonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] +is_a: GO:0042879 ! aldonate transmembrane transporter activity +relationship: part_of GO:0042875 ! D-galactonate transmembrane transport + +[Term] +id: GO:0042882 +name: L-arabinose transmembrane transport +namespace: biological_process +def: "The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl, GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-arabinose transport" RELATED [] +is_a: GO:0015751 ! arabinose transmembrane transport + +[Term] +id: GO:0042883 +name: cysteine transport +namespace: biological_process +def: "The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] +synonym: "L-cysteine transport" NARROW [] +is_a: GO:0000101 ! sulfur amino acid transport +is_a: GO:0006812 ! cation transport +is_a: GO:0015804 ! neutral amino acid transport + +[Term] +id: GO:0042884 +name: microcin transport +namespace: biological_process +def: "The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:11292337] +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0042885 +name: microcin B17 transport +namespace: biological_process +def: "The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:11292337] +is_a: GO:0042884 ! microcin transport + +[Term] +id: GO:0042886 +name: amide transport +namespace: biological_process +def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] +subset: goslim_pir +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0042887 +name: amide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] +synonym: "amine/amide/polyamine channel activity" NARROW [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0042886 ! amide transport + +[Term] +id: GO:0042888 +name: molybdenum ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity + +[Term] +id: GO:0042889 +name: 3-phenylpropionic acid transport +namespace: biological_process +def: "The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "3-phenylpropionate transport" EXACT [] +synonym: "HCA transport" EXACT [] +synonym: "hydrocinnamic acid transport" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport + +[Term] +id: GO:0042890 +name: 3-phenylpropionic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other." [GOC:jl] +synonym: "3-phenylpropionate acid transporter activity" EXACT [] +synonym: "HCA transporter activity" EXACT [] +synonym: "hydrocinnamic acid transporter activity" EXACT [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:0042889 ! 3-phenylpropionic acid transport + +[Term] +id: GO:0042891 +name: obsolete antibiotic transport +namespace: biological_process +def: "OBSOLETE. The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +comment: The reason for obsoletion is that this term has been inconsistently used. For export of an antibiotic by the organism that synthesizes it, consider 'GO:0140115 ; export across plasma membrane'. For export of an antibiotic by the target organism, consider 'GO:1990961 ; xenobiotic detoxification by transmembrane export across the plasma membrane'. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17082 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0042892 +name: chloramphenicol transmembrane transport +namespace: biological_process +def: "The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other." [PMID:29150447] +synonym: "chloramphenicol transport" BROAD [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015791 ! polyol transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0042893 +name: polymyxin transport +namespace: biological_process +def: "The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0042894 +name: fosmidomycin transport +namespace: biological_process +def: "The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:12543685] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0042895 +name: obsolete antibiotic transmembrane transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, from one side of a membrane to the other." [GOC:jl] +comment: The reason for obsoletion is that this term has been inconsistently used. Consider annotating to 'GO:0042910 ; xenobiotic transmembrane transporter activity' and the specific solute being transported as an annotation extension. +synonym: "antibiotic transporter activity" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17082 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0042896 +name: chloramphenicol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other." [GOC:jl] +synonym: "chloramphenicol transporter activity" RELATED [] +is_a: GO:0015166 ! polyol transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0042892 ! chloramphenicol transmembrane transport + +[Term] +id: GO:0042897 +name: polymyxin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] +synonym: "polymyxin transporter activity" RELATED [] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0042893 ! polymyxin transport + +[Term] +id: GO:0042898 +name: fosmidomycin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other." [GOC:jl, PMID:12543685] +synonym: "fosmidomycin transporter activity" RELATED [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +relationship: part_of GO:0042894 ! fosmidomycin transport + +[Term] +id: GO:0042899 +name: arabinan transmembrane transport +namespace: biological_process +def: "The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:jl] +synonym: "arabinan transport" RELATED [] +is_a: GO:0015774 ! polysaccharide transport +is_a: GO:0034219 ! carbohydrate transmembrane transport + +[Term] +id: GO:0042900 +name: arabinose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015146 ! pentose transmembrane transporter activity +relationship: part_of GO:0015751 ! arabinose transmembrane transport + +[Term] +id: GO:0042901 +name: arabinan transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015159 ! polysaccharide transmembrane transporter activity + +[Term] +id: GO:0042902 +name: peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein +namespace: biological_process +def: "The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan." [RESID:AA0345] +xref: RESID:AA0345 +is_a: GO:0018104 ! peptidoglycan-protein cross-linking +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0042903 +name: tubulin deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate." [PMID:12024216, PMID:12486003] +xref: Reactome:R-HSA-5618331 "HDAC6 deacetylates microtubules" +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0033558 ! protein deacetylase activity +relationship: part_of GO:0090042 ! tubulin deacetylation + +[Term] +id: GO:0042904 +name: 9-cis-retinoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative." [GOC:jl, PMID:11279029] +synonym: "9-cis-retinoic acid anabolism" EXACT [] +synonym: "9-cis-retinoic acid biosynthesis" EXACT [] +synonym: "9-cis-retinoic acid formation" EXACT [] +synonym: "9-cis-retinoic acid synthesis" EXACT [] +is_a: GO:0002138 ! retinoic acid biosynthetic process +is_a: GO:0042905 ! 9-cis-retinoic acid metabolic process + +[Term] +id: GO:0042905 +name: 9-cis-retinoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative." [GOC:jl, PMID:11279029] +synonym: "9-cis-retinoic acid metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042573 ! retinoic acid metabolic process + +[Term] +id: GO:0042906 +name: xanthine transport +namespace: biological_process +def: "The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids." [GOC:jl] +synonym: "xanthine transmembrane transport" EXACT [GOC:mah] +is_a: GO:0006863 ! purine nucleobase transport + +[Term] +id: GO:0042907 +name: xanthine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids." [GOC:jl] +is_a: GO:0005345 ! purine nucleobase transmembrane transporter activity +relationship: part_of GO:0042906 ! xanthine transport + +[Term] +id: GO:0042908 +name: xenobiotic transport +namespace: biological_process +def: "The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +subset: goslim_pir +is_a: GO:0006810 ! transport + +[Term] +id: GO:0042909 +name: acridine transport +namespace: biological_process +def: "The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, Wikipedia:Acridine] +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0042910 +name: xenobiotic transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015238 +alt_id: GO:0015239 +alt_id: GO:0015559 +alt_id: GO:0015564 +alt_id: GO:0090484 +def: "Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical." [GOC:go_curators] +subset: goslim_metagenomics +synonym: "drug transmembrane transporter activity" RELATED [] +synonym: "drug transporter activity" RELATED [] +synonym: "multidrug efflux pump activity" RELATED [] +synonym: "multidrug transporter activity" RELATED [] +synonym: "multidrug, alkane resistant pump activity" RELATED [] +synonym: "xenobiotic transporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0042908 ! xenobiotic transport + +[Term] +id: GO:0042911 +name: acridine transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene from one side of a membrane to the other." [GOC:jl] +synonym: "acridine transporter activity" RELATED [] +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0042909 ! acridine transport + +[Term] +id: GO:0042912 +name: colicin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1." [GOC:jl, GOC:mtg_transport, ISBN:0815340729, PMID:17347522] +is_a: GO:0022885 ! bacteriocin transmembrane transporter activity + +[Term] +id: GO:0042913 +name: group A colicin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729, PMID:9171417] +is_a: GO:0042912 ! colicin transmembrane transporter activity + +[Term] +id: GO:0042914 +name: colicin transport +namespace: biological_process +def: "The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1." [GOC:jl, PMID:17347522] +is_a: GO:0043213 ! bacteriocin transport + +[Term] +id: GO:0042915 +name: group A colicin transport +namespace: biological_process +def: "The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:9171417] +is_a: GO:0042914 ! colicin transport + +[Term] +id: GO:0042916 +name: alkylphosphonate transport +namespace: biological_process +def: "The directed movement of an alkylphosphonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015716 ! organic phosphonate transport + +[Term] +id: GO:0042917 +name: alkylphosphonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an alkylphosphonate from one side of a membrane to the other." [GOC:go_curators] +is_a: GO:0015604 ! organic phosphonate transmembrane transporter activity +relationship: part_of GO:0042916 ! alkylphosphonate transport + +[Term] +id: GO:0042918 +name: alkanesulfonate transport +namespace: biological_process +def: "The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical." [GOC:jl] +synonym: "alkanesulphonate transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015849 ! organic acid transport +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0042919 +name: benzoate transport +namespace: biological_process +def: "The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0721662544] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042908 ! xenobiotic transport + +[Term] +id: GO:0042920 +name: 3-hydroxyphenylpropionic acid transmembrane transport +namespace: biological_process +def: "The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other." [GOC:go_curators] +synonym: "3-(3-hydroxyphenyl)propionic acid transport" EXACT [] +synonym: "3-hydroxyphenylpropionic acid transport" BROAD [] +synonym: "m-hydroxyphenylpropionic acid transport" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0042908 ! xenobiotic transport + +[Term] +id: GO:0042921 +name: glucocorticoid receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor." [GOC:mah] +synonym: "glucocorticoid receptor signalling pathway" EXACT [] +is_a: GO:0031958 ! corticosteroid receptor signaling pathway + +[Term] +id: GO:0042922 +name: neuromedin U receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor." [GOC:jl, PMID:10899166] +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0042923 +name: neuropeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators)." [http://www.wormbook.org/chapters/www_neuropeptides/neuropeptides.html] +is_a: GO:0042277 ! peptide binding + +[Term] +id: GO:0042924 +name: neuromedin U binding +namespace: molecular_function +def: "Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses." [GOC:jl, PMID:12584108] +synonym: "NMU binding" EXACT [] +is_a: GO:0042923 ! neuropeptide binding + +[Term] +id: GO:0042925 +name: benzoate transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other." [GOC:jl, ISBN:0721662544] +synonym: "benzoate transporter activity" RELATED [] +xref: RHEA:32811 +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0042919 ! benzoate transport + +[Term] +id: GO:0042926 +name: 3-hydroxyphenylpropionic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other." [GOC:jl] +synonym: "3-(3-hydroxyphenyl)propionic acid transporter activity" EXACT [] +synonym: "3-hydroxyphenylpropionic acid transporter activity" RELATED [] +synonym: "m-hydroxyphenylpropionic acid transporter activity" EXACT [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:0042920 ! 3-hydroxyphenylpropionic acid transmembrane transport + +[Term] +id: GO:0042928 +name: ferrichrome import into cell +namespace: biological_process +def: "A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:jl, ISBN:0198506732, PMID:23192658] +synonym: "ferrichrome transport" BROAD [] +is_a: GO:0015687 ! ferric-hydroxamate import into cell +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0042929 +name: ferrichrome transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:jl, ISBN:0198506732] +synonym: "ferrichrome transporter activity" RELATED [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015343 ! siderophore transmembrane transporter activity +is_a: GO:0015603 ! iron chelate transmembrane transporter activity +is_a: GO:1904680 ! peptide transmembrane transporter activity +relationship: part_of GO:0042928 ! ferrichrome import into cell + +[Term] +id: GO:0042930 +name: enterobactin transport +namespace: biological_process +def: "The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "enterochelin transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015891 ! siderophore transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0042931 +name: enterobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other." [GOC:jl] +synonym: "enterobactin transporter activity" RELATED [] +synonym: "enterochelin transporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015343 ! siderophore transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0042930 ! enterobactin transport + +[Term] +id: GO:0042932 +name: chrysobactin transport +namespace: biological_process +def: "The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:8837459] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015891 ! siderophore transport +is_a: GO:0042938 ! dipeptide transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0042933 +name: chrysobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other." [GOC:jl, PMID:8837459] +synonym: "chrysobactin transporter activity" RELATED [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015343 ! siderophore transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:0071916 ! dipeptide transmembrane transporter activity +relationship: part_of GO:0042932 ! chrysobactin transport + +[Term] +id: GO:0042934 +name: achromobactin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other." [GOC:jl] +synonym: "achromobactin transporter activity" RELATED [] +is_a: GO:0015343 ! siderophore transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +is_a: GO:0051184 ! cofactor transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +relationship: part_of GO:0042935 ! achromobactin transport + +[Term] +id: GO:0042935 +name: achromobactin transport +namespace: biological_process +def: "The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:10928541] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015891 ! siderophore transport +is_a: GO:0042886 ! amide transport +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0042937 +name: tripeptide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other." [GOC:jl] +synonym: "tripeptide transporter activity" RELATED [] +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity +relationship: part_of GO:0042939 ! tripeptide transport + +[Term] +id: GO:0042938 +name: dipeptide transport +namespace: biological_process +def: "The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0006857 ! oligopeptide transport + +[Term] +id: GO:0042939 +name: tripeptide transport +namespace: biological_process +def: "The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0006857 ! oligopeptide transport + +[Term] +id: GO:0042940 +name: D-amino acid transport +namespace: biological_process +def: "The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, GOC:jsg, GOC:mah] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0042941 +name: D-alanine transport +namespace: biological_process +def: "The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, GOC:jsg, GOC:mah] +is_a: GO:0032328 ! alanine transport +is_a: GO:0042940 ! D-amino acid transport + +[Term] +id: GO:0042942 +name: D-serine transport +namespace: biological_process +def: "The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, GOC:jsg, GOC:mah] +is_a: GO:0015893 ! drug transport +is_a: GO:0032329 ! serine transport +is_a: GO:0042940 ! D-amino acid transport + +[Term] +id: GO:0042943 +name: D-amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids." [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729] +synonym: "D-amino acid transporter activity" BROAD [] +is_a: GO:0015171 ! amino acid transmembrane transporter activity +relationship: part_of GO:0042940 ! D-amino acid transport + +[Term] +id: GO:0042944 +name: D-alanine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +synonym: "D-alanine transporter activity" BROAD [] +is_a: GO:0022858 ! alanine transmembrane transporter activity +is_a: GO:0042943 ! D-amino acid transmembrane transporter activity +relationship: part_of GO:0042941 ! D-alanine transport + +[Term] +id: GO:0042945 +name: D-serine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid." [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0815340729] +synonym: "D-serine permease activity" EXACT [] +synonym: "D-serine transporter activity" BROAD [] +is_a: GO:0022889 ! serine transmembrane transporter activity +is_a: GO:0042943 ! D-amino acid transmembrane transporter activity +relationship: part_of GO:0042942 ! D-serine transport + +[Term] +id: GO:0042946 +name: glucoside transport +namespace: biological_process +def: "The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue." [GOC:jl, ISBN:0198506732] +is_a: GO:1901656 ! glycoside transport + +[Term] +id: GO:0042947 +name: glucoside transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0042946 ! glucoside transport + +[Term] +id: GO:0042948 +name: salicin transport +namespace: biological_process +def: "The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0015759 ! beta-glucoside transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0042949 +name: arbutin transport +namespace: biological_process +def: "The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, PMID:19965875] +is_a: GO:0015759 ! beta-glucoside transport + +[Term] +id: GO:0042950 +name: salicin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015573 ! beta-glucoside transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +relationship: part_of GO:0042948 ! salicin transport + +[Term] +id: GO:0042951 +name: arbutin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, PMID:19965875] +is_a: GO:0015573 ! beta-glucoside transmembrane transporter activity +relationship: part_of GO:0042949 ! arbutin transport + +[Term] +id: GO:0042952 +name: beta-ketoadipate pathway +namespace: biological_process +def: "A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates." [GOC:jl, PMID:8905091] +synonym: "ortho-cleavage pathway" BROAD [] +is_a: GO:0019439 ! aromatic compound catabolic process + +[Term] +id: GO:0042953 +name: lipoprotein transport +namespace: biological_process +def: "The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] +is_a: GO:0015031 ! protein transport +is_a: GO:0044872 ! lipoprotein localization + +[Term] +id: GO:0042954 +name: obsolete lipoprotein transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells." [GOC:jl, ISBN:0198506732] +comment: The reason for obsoletion is this term has been incorrectly used. +xref: Reactome:R-HSA-350168 "LRP2 transports CUBN:GC:25(OH)D from extracellular region to cytosol" +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17004 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0042955 +name: dextrin transport +namespace: biological_process +def: "The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, http://www.mercksource.com/] +is_a: GO:0015774 ! polysaccharide transport + +[Term] +id: GO:0042956 +name: maltodextrin transport +namespace: biological_process +def: "The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, http://www.mercksource.com/] +is_a: GO:0015774 ! polysaccharide transport + +[Term] +id: GO:0042957 +name: dextrin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other." [GOC:jl, GOC:vk, http://www.mercksource.com/] +is_a: GO:0015159 ! polysaccharide transmembrane transporter activity +relationship: part_of GO:0042955 ! dextrin transport + +[Term] +id: GO:0042958 +name: maltodextrin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other." [GOC:jl, http://www.mercksource.com/, PMID:15034926] +is_a: GO:0015159 ! polysaccharide transmembrane transporter activity +relationship: part_of GO:0042956 ! maltodextrin transport + +[Term] +id: GO:0042959 +name: alkanesulfonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of alkanesulfonate from one side of a membrane to the other." [GOC:jl] +synonym: "alkanesulfonate transporter activity" RELATED [] +synonym: "alkanesulphonate transporter activity" EXACT [] +is_a: GO:0005342 ! organic acid transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0042918 ! alkanesulfonate transport + +[Term] +id: GO:0042960 +name: antimonite secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:jl] +synonym: "antimonite porter activity" RELATED [] +is_a: GO:0015104 ! antimonite transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity + +[Term] +id: GO:0042961 +name: ATPase-coupled antimonite transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out)." [EC:7.3.2.7] +synonym: "antimonite ABC transporter" NARROW [] +synonym: "antimonite-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent antimonite transporter activity" EXACT [] +is_a: GO:0015104 ! antimonite transmembrane transporter activity +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity + +[Term] +id: GO:0042962 +name: acridine:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out)." [PMID:10735876] +synonym: "acridine efflux pump activity" RELATED [] +synonym: "acridine:hydrogen antiporter activity" EXACT [] +is_a: GO:0015299 ! solute:proton antiporter activity + +[Term] +id: GO:0042964 +name: thioredoxin reduction +namespace: biological_process +def: "The chemical reactions and pathways resulting in the reduction of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase." [GOC:go_curators] +synonym: "thioredoxin anabolism" EXACT [] +synonym: "thioredoxin biosynthesis" EXACT [] +synonym: "thioredoxin formation" EXACT [] +synonym: "thioredoxin synthesis" EXACT [] +is_a: GO:0055114 ! oxidation-reduction process + +[Term] +id: GO:0042965 +name: obsolete glutaredoxin biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase." [GOC:go_curators] +comment: This term was made obsolete because it refers to the biosynthesis of a protein. +synonym: "glutaredoxin anabolism" EXACT [] +synonym: "glutaredoxin biosynthesis" EXACT [] +synonym: "glutaredoxin formation" EXACT [] +synonym: "glutaredoxin synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042966 +name: biotin carboxyl carrier protein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase." [GOC:go_curators, PMID:8102363] +synonym: "BCCP biosynthesis" EXACT [] +synonym: "BCCP biosynthetic process" EXACT [] +synonym: "biotin carboxyl carrier protein anabolism" EXACT [] +synonym: "biotin carboxyl carrier protein biosynthesis" EXACT [] +synonym: "biotin carboxyl carrier protein formation" EXACT [] +synonym: "biotin carboxyl carrier protein synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0042967 +name: obsolete acyl-carrier-protein biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of acyl-carrier protein." [GOC:go_curators] +comment: The reason for obsoletion is that acyl-carrier-protein is synthesized by the ribosome like any other protein. +synonym: "ACP biosynthesis" EXACT [] +synonym: "ACP biosynthetic process" EXACT [] +synonym: "acyl carrier protein biosynthesis" EXACT [] +synonym: "acyl carrier protein biosynthetic process" EXACT [] +synonym: "acyl-carrier protein biosynthesis" EXACT [] +synonym: "acyl-carrier-protein anabolism" EXACT [] +synonym: "acyl-carrier-protein biosynthesis" EXACT [] +synonym: "acyl-carrier-protein formation" EXACT [] +synonym: "acyl-carrier-protein synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042968 +name: homoserine transport +namespace: biological_process +def: "The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators, ISBN:0198506732] +is_a: GO:0015804 ! neutral amino acid transport +is_a: GO:0015807 ! L-amino acid transport + +[Term] +id: GO:0042969 +name: lactone transport +namespace: biological_process +def: "The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:go_curators] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0042970 +name: homoserine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine." [GOC:go_curators, ISBN:0198506732] +synonym: "homoserine transporter activity" BROAD [] +is_a: GO:0015175 ! neutral amino acid transmembrane transporter activity +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +relationship: part_of GO:0042968 ! homoserine transport + +[Term] +id: GO:0042971 +name: lactone transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:go_curators] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0042969 ! lactone transport + +[Term] +id: GO:0042972 +name: licheninase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds." [EC:3.2.1.73] +synonym: "1,3-1,4-beta-D-glucan 4-glucanohydrolase activity" EXACT [] +synonym: "1,3-1,4-beta-glucan 4-glucanohydrolase activity" EXACT [] +synonym: "1,3;1,4-beta-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.73] +synonym: "1,3;1,4-beta-glucan endohydrolase activity" EXACT [EC:3.2.1.73] +synonym: "beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.73] +synonym: "beta-glucanase activity" BROAD [EC:3.2.1.73] +synonym: "endo-beta-1,3-1,4 glucanase activity" EXACT [EC:3.2.1.73] +synonym: "lichenase activity" EXACT [] +synonym: "mixed linkage beta-glucanase activity" RELATED [EC:3.2.1.73] +xref: EC:3.2.1.73 +xref: MetaCyc:3.2.1.73-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0042973 +name: glucan endo-1,3-beta-D-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans." [EC:3.2.1.39] +synonym: "(1->3)-beta-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.39] +synonym: "(1->3)-beta-glucan endohydrolase activity" EXACT [EC:3.2.1.39] +synonym: "1,3-beta-D-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.39] +synonym: "1,3-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.39] +synonym: "beta-1,3-glucanase" BROAD [EC:3.2.1.39] +synonym: "callase activity" EXACT [EC:3.2.1.39] +synonym: "endo-(1,3)-beta-D-glucanase activity" BROAD [EC:3.2.1.39] +synonym: "endo-(1->3)-beta-D-glucanase activity" BROAD [EC:3.2.1.39] +synonym: "endo-1,3-beta-D-glucanase" BROAD [EC:3.2.1.39] +synonym: "endo-1,3-beta-glucanase activity" BROAD [] +synonym: "endo-1,3-beta-glucosidase activity" BROAD [EC:3.2.1.39] +synonym: "kitalase activity" EXACT [EC:3.2.1.39] +synonym: "laminaranase activity" BROAD [] +synonym: "laminarinase activity" BROAD [] +synonym: "oligo-1,3-glucosidase activity" RELATED [EC:3.2.1.39] +xref: EC:3.2.1.39 +xref: MetaCyc:3.2.1.39-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0042974 +name: retinoic acid receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily." [GOC:jl, PMID:12476796] +synonym: "RAR binding" EXACT [] +is_a: GO:0035257 ! nuclear hormone receptor binding + +[Term] +id: GO:0042975 +name: peroxisome proliferator activated receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma." [GOC:jl, PMID:12769781] +synonym: "PPAR binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0042976 +name: activation of Janus kinase activity +namespace: biological_process +alt_id: GO:0010531 +alt_id: GO:0042977 +def: "The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:jl, PMID:12479803] +synonym: "activation of JAK protein" EXACT [GOC:dph, GOC:tb] +synonym: "activation of JAK protein by tyrosine phosphorylation" EXACT [] +synonym: "activation of JAK1 kinase activity" NARROW [] +synonym: "activation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "activation of JAK2 kinase activity" NARROW [] +synonym: "activation of JAK2 protein" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of JAK protein activity by tyrosine phosphorylation" EXACT [] +synonym: "tyrosine phosphorylation of JAK protein" EXACT [] +synonym: "tyrosine phosphorylation of JAK1 protein" NARROW [GOC:dph, GOC:tb] +synonym: "tyrosine phosphorylation of JAK2 protein" NARROW [] +is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation +is_a: GO:0032147 ! activation of protein kinase activity +relationship: part_of GO:0046427 ! positive regulation of receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0042978 +name: ornithine decarboxylase activator activity +namespace: molecular_function +def: "Upregulation of the activity of the enzyme ornithine decarboxylase." [GOC:jl] +synonym: "L-ornithine carboxy-lyase activator activity" NARROW [] +is_a: GO:0008047 ! enzyme activator activity +is_a: GO:0042979 ! ornithine decarboxylase regulator activity +relationship: positively_regulates GO:0004586 ! ornithine decarboxylase activity + +[Term] +id: GO:0042979 +name: ornithine decarboxylase regulator activity +namespace: molecular_function +def: "Modulation of the activity of the enzyme ornithine decarboxylase." [GOC:jl] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0004586 ! ornithine decarboxylase activity + +[Term] +id: GO:0042980 +name: obsolete cystic fibrosis transmembrane conductance regulator binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein." [GOC:jl] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "CFTR binding" EXACT [] +synonym: "cystic fibrosis transmembrane conductance regulator binding" EXACT [] +is_obsolete: true +replaced_by: GO:0044325 + +[Term] +id: GO:0042981 +name: regulation of apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] +comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. +synonym: "apoptosis regulator activity" RELATED [] +synonym: "regulation of apoptosis" NARROW [] +is_a: GO:0043067 ! regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006915 ! apoptotic process +relationship: regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0042982 +name: amyloid precursor protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease." [GOC:go_curators] +synonym: "amyloid precursor protein metabolism" EXACT [] +synonym: "APP metabolic process" EXACT [] +synonym: "APP metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process + +[Term] +id: GO:0042983 +name: amyloid precursor protein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease." [GOC:go_curators] +synonym: "amyloid precursor protein anabolism" EXACT [] +synonym: "amyloid precursor protein biosynthesis" EXACT [] +synonym: "amyloid precursor protein formation" EXACT [] +synonym: "amyloid precursor protein synthesis" EXACT [] +synonym: "APP biosynthesis" EXACT [] +synonym: "APP biosynthetic process" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0042982 ! amyloid precursor protein metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0042984 +name: regulation of amyloid precursor protein biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta." [GOC:go_curators] +synonym: "regulation of amyloid precursor protein anabolism" EXACT [] +synonym: "regulation of amyloid precursor protein biosynthesis" EXACT [] +synonym: "regulation of amyloid precursor protein formation" EXACT [] +synonym: "regulation of amyloid precursor protein synthesis" EXACT [] +synonym: "regulation of APP biosynthesis" EXACT [] +synonym: "regulation of APP biosynthetic process" EXACT [] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042983 ! amyloid precursor protein biosynthetic process +relationship: regulates GO:0042983 ! amyloid precursor protein biosynthetic process + +[Term] +id: GO:0042985 +name: negative regulation of amyloid precursor protein biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta." [GOC:go_curators] +synonym: "down regulation of amyloid precursor protein biosynthetic process" EXACT [] +synonym: "down-regulation of amyloid precursor protein biosynthetic process" EXACT [] +synonym: "downregulation of amyloid precursor protein biosynthetic process" EXACT [] +synonym: "inhibition of amyloid precursor protein biosynthetic process" NARROW [] +synonym: "negative regulation of amyloid precursor protein anabolism" EXACT [] +synonym: "negative regulation of amyloid precursor protein biosynthesis" EXACT [] +synonym: "negative regulation of amyloid precursor protein formation" EXACT [] +synonym: "negative regulation of amyloid precursor protein synthesis" EXACT [] +synonym: "negative regulation of APP biosynthesis" EXACT [] +synonym: "negative regulation of APP biosynthetic process" EXACT [] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0042984 ! regulation of amyloid precursor protein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042983 ! amyloid precursor protein biosynthetic process +relationship: negatively_regulates GO:0042983 ! amyloid precursor protein biosynthetic process + +[Term] +id: GO:0042986 +name: positive regulation of amyloid precursor protein biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta." [GOC:go_curators] +synonym: "activation of amyloid precursor protein biosynthetic process" NARROW [] +synonym: "positive regulation of amyloid precursor protein anabolism" EXACT [] +synonym: "positive regulation of amyloid precursor protein biosynthesis" EXACT [] +synonym: "positive regulation of amyloid precursor protein formation" EXACT [] +synonym: "positive regulation of amyloid precursor protein synthesis" EXACT [] +synonym: "positive regulation of APP biosynthesis" EXACT [] +synonym: "positive regulation of APP biosynthetic process" EXACT [] +synonym: "stimulation of amyloid precursor protein biosynthetic process" NARROW [] +synonym: "up regulation of amyloid precursor protein biosynthetic process" EXACT [] +synonym: "up-regulation of amyloid precursor protein biosynthetic process" EXACT [] +synonym: "upregulation of amyloid precursor protein biosynthetic process" EXACT [] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0042984 ! regulation of amyloid precursor protein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042983 ! amyloid precursor protein biosynthetic process +relationship: positively_regulates GO:0042983 ! amyloid precursor protein biosynthetic process + +[Term] +id: GO:0042987 +name: amyloid precursor protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease." [GOC:go_curators] +synonym: "amyloid precursor protein breakdown" EXACT [] +synonym: "amyloid precursor protein catabolism" EXACT [] +synonym: "amyloid precursor protein degradation" EXACT [] +synonym: "APP catabolic process" EXACT [] +synonym: "APP catabolism" EXACT [] +is_a: GO:0042982 ! amyloid precursor protein metabolic process + +[Term] +id: GO:0042988 +name: X11-like protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein." [GOC:jl, PMID:12780348] +synonym: "X11L binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0042989 +name: sequestering of actin monomers +namespace: biological_process +def: "The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers." [GOC:go_curators] +synonym: "actin monomer retention" EXACT [] +synonym: "actin monomer sequestering" EXACT [] +synonym: "actin monomer sequestering activity" RELATED [] +synonym: "actin monomer sequestration" EXACT [] +synonym: "actin monomer storage" EXACT [] +synonym: "retention of actin monomers" EXACT [] +synonym: "sequestration of actin monomers" EXACT [] +synonym: "storage of actin monomers" EXACT [] +is_a: GO:0030837 ! negative regulation of actin filament polymerization +is_a: GO:0032507 ! maintenance of protein location in cell + +[Term] +id: GO:0042990 +name: obsolete regulation of transcription factor import into nucleus +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus." [GOC:jl] +comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus. +synonym: "regulation of transcription factor import into cell nucleus" EXACT [] +synonym: "regulation of transcription factor transport from cytoplasm to nucleus" EXACT [] +synonym: "regulation of transcription factor-nucleus import" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042991 +name: obsolete transcription factor import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a transcription factor from the cytoplasm to the nucleus." [GOC:jl] +comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus. +synonym: "transcription factor import into cell nucleus" EXACT [] +synonym: "transcription factor transport from cytoplasm to nucleus" EXACT [] +synonym: "transcription factor-nucleus import" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042992 +name: obsolete negative regulation of transcription factor import into nucleus +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus." [GOC:jl] +comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus. +synonym: "down regulation of transcription factor import into nucleus" EXACT [] +synonym: "down-regulation of transcription factor import into nucleus" EXACT [] +synonym: "downregulation of transcription factor import into nucleus" EXACT [] +synonym: "inhibition of transcription factor import into nucleus" NARROW [] +synonym: "negative regulation of transcription factor import into cell nucleus" EXACT [] +synonym: "negative regulation of transcription factor transport from cytoplasm to nucleus" EXACT [] +synonym: "negative regulation of transcription factor-nucleus import" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042993 +name: obsolete positive regulation of transcription factor import into nucleus +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus." [GOC:jl] +comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus. +synonym: "activation of transcription factor import into nucleus" NARROW [] +synonym: "positive regulation of transcription factor import into cell nucleus" EXACT [] +synonym: "positive regulation of transcription factor transport from cytoplasm to nucleus" EXACT [] +synonym: "positive regulation of transcription factor-nucleus import" EXACT [] +synonym: "stimulation of transcription factor import into nucleus" NARROW [] +synonym: "up regulation of transcription factor import into nucleus" EXACT [] +synonym: "up-regulation of transcription factor import into nucleus" EXACT [] +synonym: "upregulation of transcription factor import into nucleus" EXACT [] +is_obsolete: true + +[Term] +id: GO:0042994 +name: cytoplasmic sequestering of transcription factor +namespace: biological_process +def: "The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus." [GOC:jl] +synonym: "cytoplasmic retention of transcription factor" EXACT [] +synonym: "cytoplasmic sequestration of transcription factor" EXACT [] +synonym: "cytoplasmic storage of transcription factor" EXACT [] +synonym: "maintenance of transcription factor protein location in cytoplasm" EXACT [GOC:dph, GOC:tb] +synonym: "retention of transcription factor in cytoplasm" EXACT [] +synonym: "sequestering of transcription factor in cytoplasm" EXACT [] +synonym: "sequestration of transcription factor in cytoplasm" EXACT [] +synonym: "storage of transcription factor in cytoplasm" EXACT [] +synonym: "transcription factor binding, cytoplasmic sequestering" EXACT [] +is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity +is_a: GO:0051220 ! cytoplasmic sequestering of protein + +[Term] +id: GO:0042995 +name: cell projection +namespace: cellular_component +def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] +subset: goslim_agr +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pir +synonym: "cell process" BROAD [] +synonym: "cellular process" BROAD [] +synonym: "cellular projection" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0042996 +name: regulation of Golgi to plasma membrane protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903076 ! regulation of protein localization to plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043001 ! Golgi to plasma membrane protein transport +relationship: regulates GO:0043001 ! Golgi to plasma membrane protein transport + +[Term] +id: GO:0042997 +name: negative regulation of Golgi to plasma membrane protein transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] +synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT [] +synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT [] +synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT [] +synonym: "inhibition of Golgi to plasma membrane protein transport" NARROW [] +is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport +relationship: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport + +[Term] +id: GO:0042998 +name: positive regulation of Golgi to plasma membrane protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] +synonym: "activation of Golgi to plasma membrane protein transport" NARROW [] +synonym: "stimulation of Golgi to plasma membrane protein transport" NARROW [] +synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT [] +synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT [] +synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT [] +is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport +relationship: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport + +[Term] +id: GO:0042999 +name: regulation of Golgi to plasma membrane CFTR protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane." [GOC:jl] +is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport +relationship: regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport + +[Term] +id: GO:0043000 +name: Golgi to plasma membrane CFTR protein transport +namespace: biological_process +def: "The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane." [GOC:jl] +synonym: "Golgi to plasma membrane cystic fibrosis transmembrane conductance regulator protein transport" EXACT [] +is_a: GO:0043001 ! Golgi to plasma membrane protein transport + +[Term] +id: GO:0043001 +name: Golgi to plasma membrane protein transport +namespace: biological_process +def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363] +is_a: GO:0006893 ! Golgi to plasma membrane transport +is_a: GO:0015031 ! protein transport +is_a: GO:0061951 ! establishment of protein localization to plasma membrane + +[Term] +id: GO:0043002 +name: negative regulation of Golgi to plasma membrane CFTR protein transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane." [GOC:jl] +synonym: "down regulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +synonym: "down-regulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +synonym: "downregulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +synonym: "inhibition of Golgi to plasma membrane CFTR protein transport" NARROW [] +is_a: GO:0042997 ! negative regulation of Golgi to plasma membrane protein transport +is_a: GO:0042999 ! regulation of Golgi to plasma membrane CFTR protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport +relationship: negatively_regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport + +[Term] +id: GO:0043003 +name: positive regulation of Golgi to plasma membrane CFTR protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane." [GOC:jl] +synonym: "activation of Golgi to plasma membrane CFTR protein transport" NARROW [] +synonym: "stimulation of Golgi to plasma membrane CFTR protein transport" NARROW [] +synonym: "up regulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +synonym: "up-regulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +synonym: "upregulation of Golgi to plasma membrane CFTR protein transport" EXACT [] +is_a: GO:0042998 ! positive regulation of Golgi to plasma membrane protein transport +is_a: GO:0042999 ! regulation of Golgi to plasma membrane CFTR protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport +relationship: positively_regulates GO:0043000 ! Golgi to plasma membrane CFTR protein transport + +[Term] +id: GO:0043004 +name: cytoplasmic sequestering of CFTR protein +namespace: biological_process +def: "The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane." [GOC:jl] +synonym: "cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein" EXACT [] +synonym: "cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein" EXACT [] +synonym: "cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)" EXACT [] +synonym: "cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein" EXACT [] +synonym: "maintenance of CFTR protein location in cytoplasm" EXACT [GOC:dph, GOC:tb] +synonym: "retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm" EXACT [] +synonym: "sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm" EXACT [] +synonym: "sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm" EXACT [] +synonym: "storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm" EXACT [] +is_a: GO:0043002 ! negative regulation of Golgi to plasma membrane CFTR protein transport +is_a: GO:0051220 ! cytoplasmic sequestering of protein + +[Term] +id: GO:0043005 +name: neuron projection +namespace: cellular_component +def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] +subset: goslim_pir +synonym: "nerve fiber" RELATED [GOC:dph] +synonym: "neurite" NARROW [] +synonym: "neuron process" EXACT [] +synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889] +synonym: "neuronal cell projection" EXACT [] +xref: NIF_Subcellular:sao867568886 +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0043006 +name: activation of phospholipase A2 activity by calcium-mediated signaling +namespace: biological_process +def: "A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal." [GOC:dph, GOC:jl, GOC:tb] +synonym: "activation of phospholipase A2 activity by calcium-mediated signalling" EXACT [GOC:mah] +synonym: "calcium-dependent activation of phospholipase A2" EXACT [GOC:dph, GOC:tb] +synonym: "calcium-dependent phospholipase A2 activation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0019722 ! calcium-mediated signaling +is_a: GO:0032431 ! activation of phospholipase A2 activity + +[Term] +id: GO:0043007 +name: maintenance of rDNA +namespace: biological_process +def: "Any process involved in sustaining the fidelity and copy number of rDNA repeats." [GOC:vw, PMID:14528010] +synonym: "rDNA maintenance" EXACT [] +synonym: "ribosomal DNA maintenance" EXACT [] +is_a: GO:0043570 ! maintenance of DNA repeat elements + +[Term] +id: GO:0043008 +name: ATP-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP." [GOC:jl] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0043009 +name: chordate embryonic development +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu] +is_a: GO:0009792 ! embryo development ending in birth or egg hatching + +[Term] +id: GO:0043010 +name: camera-type eye development +namespace: biological_process +alt_id: GO:0001747 +alt_id: GO:0031075 +def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu] +is_a: GO:0001654 ! eye development + +[Term] +id: GO:0043011 +name: myeloid dendritic cell differentiation +namespace: biological_process +def: "The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin." [CL:0000782, GOC:jl] +xref: Wikipedia:Dendritic_cell +is_a: GO:0001773 ! myeloid dendritic cell activation +is_a: GO:0002573 ! myeloid leukocyte differentiation +is_a: GO:0097028 ! dendritic cell differentiation + +[Term] +id: GO:0043012 +name: regulation of fusion of sperm to egg plasma membrane +namespace: biological_process +def: "Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane." [GOC:jl, PMID:11483596] +synonym: "regulation of sperm-oocyte fusion" NARROW [] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0080154 ! regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007342 ! fusion of sperm to egg plasma membrane involved in single fertilization +relationship: regulates GO:0007342 ! fusion of sperm to egg plasma membrane involved in single fertilization + +[Term] +id: GO:0043013 +name: negative regulation of fusion of sperm to egg plasma membrane +namespace: biological_process +def: "Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane." [GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html] +synonym: "down regulation of fusion of sperm to egg plasma membrane" EXACT [] +synonym: "down-regulation of fusion of sperm to egg plasma membrane" EXACT [] +synonym: "downregulation of fusion of sperm to egg plasma membrane" EXACT [] +synonym: "inhibition of fusion of sperm to egg plasma membrane" NARROW [] +synonym: "inhibition of sperm-oocyte fusion" NARROW [] +synonym: "negative regulation of sperm-oocyte fusion" NARROW [] +is_a: GO:0043012 ! regulation of fusion of sperm to egg plasma membrane +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060467 ! negative regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007342 ! fusion of sperm to egg plasma membrane involved in single fertilization +relationship: negatively_regulates GO:0007342 ! fusion of sperm to egg plasma membrane involved in single fertilization + +[Term] +id: GO:0043014 +name: alpha-tubulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin." [GOC:jl] +synonym: "alpha tubulin binding" EXACT [] +is_a: GO:0015631 ! tubulin binding + +[Term] +id: GO:0043015 +name: gamma-tubulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin." [GOC:jl] +synonym: "gamma tubulin binding" EXACT [] +is_a: GO:0015631 ! tubulin binding + +[Term] +id: GO:0043016 +name: regulation of lymphotoxin A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] +synonym: "regulation of LTA biosynthesis" EXACT [] +synonym: "regulation of LTA biosynthetic process" EXACT [] +synonym: "regulation of lymphotoxin A anabolism" EXACT [] +synonym: "regulation of lymphotoxin A biosynthesis" EXACT [] +synonym: "regulation of lymphotoxin A formation" EXACT [] +synonym: "regulation of lymphotoxin A synthesis" EXACT [] +synonym: "regulation of lymphotoxin-alpha biosynthesis" EXACT [] +synonym: "regulation of lymphotoxin-alpha biosynthetic process" EXACT [] +synonym: "regulation of TNF-B biosynthesis" EXACT [] +synonym: "regulation of TNF-B biosynthetic process" EXACT [] +synonym: "regulation of TNF-beta biosynthesis" EXACT [] +synonym: "regulation of TNF-beta biosynthetic process" EXACT [] +synonym: "regulation of tumor necrosis factor-beta biosynthesis" EXACT [] +synonym: "regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] +is_a: GO:0032681 ! regulation of lymphotoxin A production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042109 ! lymphotoxin A biosynthetic process +relationship: regulates GO:0042109 ! lymphotoxin A biosynthetic process + +[Term] +id: GO:0043017 +name: positive regulation of lymphotoxin A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] +synonym: "activation of lymphotoxin A biosynthetic process" NARROW [] +synonym: "positive regulation of LTA biosynthesis" EXACT [] +synonym: "positive regulation of LTA biosynthetic process" EXACT [] +synonym: "positive regulation of lymphotoxin A anabolism" EXACT [] +synonym: "positive regulation of lymphotoxin A biosynthesis" EXACT [] +synonym: "positive regulation of lymphotoxin A formation" EXACT [] +synonym: "positive regulation of lymphotoxin A synthesis" EXACT [] +synonym: "positive regulation of lymphotoxin-alpha biosynthesis" EXACT [] +synonym: "positive regulation of lymphotoxin-alpha biosynthetic process" EXACT [] +synonym: "positive regulation of TNF-B biosynthesis" EXACT [] +synonym: "positive regulation of TNF-B biosynthetic process" EXACT [] +synonym: "positive regulation of TNF-beta biosynthesis" EXACT [] +synonym: "positive regulation of TNF-beta biosynthetic process" EXACT [] +synonym: "positive regulation of tumor necrosis factor-beta biosynthesis" EXACT [] +synonym: "positive regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] +synonym: "stimulation of lymphotoxin A biosynthetic process" NARROW [] +synonym: "up regulation of lymphotoxin A biosynthetic process" EXACT [] +synonym: "up-regulation of lymphotoxin A biosynthetic process" EXACT [] +synonym: "upregulation of lymphotoxin A biosynthetic process" EXACT [] +is_a: GO:0032761 ! positive regulation of lymphotoxin A production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0043016 ! regulation of lymphotoxin A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042109 ! lymphotoxin A biosynthetic process +relationship: positively_regulates GO:0042109 ! lymphotoxin A biosynthetic process + +[Term] +id: GO:0043018 +name: negative regulation of lymphotoxin A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] +synonym: "down regulation of lymphotoxin A biosynthetic process" EXACT [] +synonym: "down-regulation of lymphotoxin A biosynthetic process" EXACT [] +synonym: "downregulation of lymphotoxin A biosynthetic process" EXACT [] +synonym: "inhibition of lymphotoxin A biosynthetic process" NARROW [] +synonym: "negative regulation of LTA biosynthesis" EXACT [] +synonym: "negative regulation of LTA biosynthetic process" EXACT [] +synonym: "negative regulation of lymphotoxin A anabolism" EXACT [] +synonym: "negative regulation of lymphotoxin A biosynthesis" EXACT [] +synonym: "negative regulation of lymphotoxin A formation" EXACT [] +synonym: "negative regulation of lymphotoxin A synthesis" EXACT [] +synonym: "negative regulation of lymphotoxin-alpha biosynthesis" EXACT [] +synonym: "negative regulation of lymphotoxin-alpha biosynthetic process" EXACT [] +synonym: "negative regulation of TNF-B biosynthesis" EXACT [] +synonym: "negative regulation of TNF-B biosynthetic process" EXACT [] +synonym: "negative regulation of TNF-beta biosynthesis" EXACT [] +synonym: "negative regulation of TNF-beta biosynthetic process" EXACT [] +synonym: "negative regulation of tumor necrosis factor-beta biosynthesis" EXACT [] +synonym: "negative regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] +is_a: GO:0032721 ! negative regulation of lymphotoxin A production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0043016 ! regulation of lymphotoxin A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042109 ! lymphotoxin A biosynthetic process +relationship: negatively_regulates GO:0042109 ! lymphotoxin A biosynthetic process + +[Term] +id: GO:0043020 +name: NADPH oxidase complex +namespace: cellular_component +def: "A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2." [GOC:jl, PMID:11483596, PMID:12440767] +synonym: "flavocytochrome b558" NARROW [] +synonym: "respiratory-burst oxidase" RELATED [] +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0043021 +name: ribonucleoprotein complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any complex of RNA and protein." [GOC:bf, GOC:go_curators, GOC:vk] +subset: goslim_pir +synonym: "protein-RNA complex binding" EXACT [GOC:bf, GOC:vk] +synonym: "ribonucleoprotein binding" EXACT [GOC:bf, GOC:vk] +synonym: "RNP binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0043022 +name: ribosome binding +namespace: molecular_function +alt_id: GO:0030376 +def: "Interacting selectively and non-covalently with any part of a ribosome." [GOC:go_curators] +synonym: "ribosome receptor activity" NARROW [] +is_a: GO:0043021 ! ribonucleoprotein complex binding + +[Term] +id: GO:0043023 +name: ribosomal large subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of the larger ribosomal subunit." [GOC:go_curators] +is_a: GO:0043021 ! ribonucleoprotein complex binding + +[Term] +id: GO:0043024 +name: ribosomal small subunit binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of the small ribosomal subunit." [GOC:go_curators] +is_a: GO:0043021 ! ribonucleoprotein complex binding + +[Term] +id: GO:0043025 +name: neuronal cell body +namespace: cellular_component +def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators] +comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. +subset: goslim_pir +synonym: "neuron cell body" EXACT [] +synonym: "neuronal cell soma" EXACT [] +xref: NIF_Subcellular:sao1044911821 +xref: Wikipedia:Soma_(biology) +is_a: GO:0044297 ! cell body +relationship: part_of GO:0036477 ! somatodendritic compartment + +[Term] +id: GO:0043027 +name: cysteine-type endopeptidase inhibitor activity involved in apoptotic process +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process." [GOC:jl, GOC:mtg_apoptosis, PMID:14744432, Wikipedia:Caspase] +synonym: "caspase inhibitor activity" BROAD [] +is_a: GO:0004869 ! cysteine-type endopeptidase inhibitor activity +is_a: GO:0043028 ! cysteine-type endopeptidase regulator activity involved in apoptotic process +intersection_of: GO:0004869 ! cysteine-type endopeptidase inhibitor activity +intersection_of: part_of GO:0006915 ! apoptotic process +relationship: part_of GO:0006915 ! apoptotic process +relationship: part_of GO:0043154 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0043028 +name: cysteine-type endopeptidase regulator activity involved in apoptotic process +namespace: molecular_function +def: "Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process." [GOC:jl, GOC:mtg_apoptosis, PMID:14744432, Wikipedia:Caspase] +synonym: "caspase regulator activity" BROAD [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: part_of GO:0043281 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0043029 +name: T cell homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149] +comment: Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus. +synonym: "T lymphocyte homeostasis" EXACT [] +synonym: "T-cell homeostasis" EXACT [] +synonym: "T-lymphocyte homeostasis" EXACT [] +is_a: GO:0002260 ! lymphocyte homeostasis + +[Term] +id: GO:0043030 +name: regulation of macrophage activation +namespace: biological_process +def: "Any process that modulates the frequency or rate of macrophage activation." [GOC:jl] +synonym: "regulation of macrophage polarization" EXACT [] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042116 ! macrophage activation +relationship: regulates GO:0042116 ! macrophage activation + +[Term] +id: GO:0043031 +name: negative regulation of macrophage activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation." [GOC:jl] +synonym: "down regulation of macrophage activation" EXACT [] +synonym: "down-regulation of macrophage activation" EXACT [] +synonym: "downregulation of macrophage activation" EXACT [] +synonym: "inhibition of macrophage activation" NARROW [] +synonym: "negative regulation of macrophage polarization" EXACT [] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:0043030 ! regulation of macrophage activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042116 ! macrophage activation +relationship: negatively_regulates GO:0042116 ! macrophage activation + +[Term] +id: GO:0043032 +name: positive regulation of macrophage activation +namespace: biological_process +def: "Any process that stimulates, induces or increases the rate of macrophage activation." [GOC:jl] +synonym: "activation of macrophage activation" NARROW [] +synonym: "positive regulation of macrophage polarization" EXACT [] +synonym: "stimulation of macrophage activation" NARROW [] +synonym: "up regulation of macrophage activation" EXACT [] +synonym: "up-regulation of macrophage activation" EXACT [] +synonym: "upregulation of macrophage activation" EXACT [] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:0043030 ! regulation of macrophage activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042116 ! macrophage activation +relationship: positively_regulates GO:0042116 ! macrophage activation + +[Term] +id: GO:0043033 +name: isoamylase complex +namespace: cellular_component +def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages." [GOC:jl, PMID:10333591] +subset: goslim_pir +synonym: "debranching enzyme complex" BROAD [] +is_a: GO:1902494 ! catalytic complex + +[Term] +id: GO:0043034 +name: costamere +namespace: cellular_component +def: "Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732, PMID:6405378] +xref: Wikipedia:Costamere +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030016 ! myofibril + +[Term] +id: GO:0043035 +name: chromatin insulator sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription." [GOC:jl, PMID:12783795] +is_a: GO:0031490 ! chromatin DNA binding + +[Term] +id: GO:0043036 +name: starch grain +namespace: cellular_component +def: "Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, PMID:11217978] +synonym: "starch granule" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009536 ! plastid + +[Term] +id: GO:0043038 +name: amino acid activation +namespace: biological_process +def: "The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule." [GOC:jl] +is_a: GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0043039 +name: tRNA aminoacylation +namespace: biological_process +def: "The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." [GOC:ma, GOC:mah, MetaCyc:Aminoacyl-tRNAs] +synonym: "aminoacyl-tRNA biosynthesis" EXACT [GOC:mah] +synonym: "aminoacyl-tRNA biosynthetic process" EXACT [GOC:mah] +synonym: "tRNA charging" EXACT [] +is_a: GO:0006399 ! tRNA metabolic process +is_a: GO:0043038 ! amino acid activation + +[Term] +id: GO:0043040 +name: tRNA aminoacylation for nonribosomal peptide biosynthetic process +namespace: biological_process +def: "The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis." [GOC:jl] +synonym: "tRNA aminoacylation for nonribosomal peptide anabolism" EXACT [] +synonym: "tRNA aminoacylation for nonribosomal peptide biosynthesis" EXACT [] +synonym: "tRNA aminoacylation for nonribosomal peptide formation" EXACT [] +synonym: "tRNA aminoacylation for nonribosomal peptide synthesis" EXACT [] +is_a: GO:0043039 ! tRNA aminoacylation +is_a: GO:0043041 ! amino acid activation for nonribosomal peptide biosynthetic process + +[Term] +id: GO:0043041 +name: amino acid activation for nonribosomal peptide biosynthetic process +namespace: biological_process +def: "Activation of an amino acid for incorporation into a peptide by a nonribosomal process." [GOC:jl] +synonym: "nonribosomal amino acid activation" RELATED [] +is_a: GO:0043038 ! amino acid activation +relationship: part_of GO:0019184 ! nonribosomal peptide biosynthetic process + +[Term] +id: GO:0043042 +name: amino acid adenylylation by nonribosomal peptide synthase +namespace: biological_process +def: "Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor." [GOC:jl, PMID:9250661, PMID:9712910] +synonym: "amino acid adenylation by nonribosomal peptide synthase" EXACT [] +synonym: "amino acid adenylation by NRPS" EXACT [] +is_a: GO:0043041 ! amino acid activation for nonribosomal peptide biosynthetic process + +[Term] +id: GO:0043043 +name: peptide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl] +synonym: "peptide anabolism" EXACT [] +synonym: "peptide biosynthesis" EXACT [] +synonym: "peptide formation" EXACT [] +synonym: "peptide synthesis" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0043044 +name: ATP-dependent chromatin remodeling +namespace: biological_process +def: "Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors." [GOC:jl, PMID:12042764] +synonym: "ATP-dependent chromatin remodelling" EXACT [] +is_a: GO:0006338 ! chromatin remodeling + +[Term] +id: GO:0043045 +name: DNA methylation involved in embryo development +namespace: biological_process +def: "The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression." [GOC:go_curators, PMID:12138111] +synonym: "de novo DNA methylation" RELATED [] +is_a: GO:0006306 ! DNA methylation +is_a: GO:1901538 ! changes to DNA methylation involved in embryo development +intersection_of: GO:0006306 ! DNA methylation +intersection_of: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0043046 +name: DNA methylation involved in gamete generation +namespace: biological_process +def: "The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete." [GOC:go_curators, PMID:12138111] +synonym: "de novo DNA methylation" RELATED [] +is_a: GO:0006306 ! DNA methylation +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +intersection_of: GO:0006306 ! DNA methylation +intersection_of: part_of GO:0007276 ! gamete generation +relationship: part_of GO:0007276 ! gamete generation + +[Term] +id: GO:0043047 +name: single-stranded telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with single-stranded telomere-associated DNA." [GOC:jl, ISBN:0321000382] +synonym: "telomeric ssDNA binding" EXACT [GOC:mah] +is_a: GO:0042162 ! telomeric DNA binding +is_a: GO:0098847 ! sequence-specific single stranded DNA binding + +[Term] +id: GO:0043048 +name: dolichyl monophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative." [GOC:jl] +synonym: "dolichyl monophosphate anabolism" EXACT [] +synonym: "dolichyl monophosphate biosynthesis" EXACT [] +synonym: "dolichyl monophosphate formation" EXACT [] +synonym: "dolichyl monophosphate synthesis" EXACT [] +is_a: GO:0008654 ! phospholipid biosynthetic process + +[Term] +id: GO:0043049 +name: otic placode formation +namespace: biological_process +def: "The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain." [GOC:go_curators, PMID:12668634] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0030916 ! otic vesicle formation + +[Term] +id: GO:0043050 +name: pharyngeal pumping +namespace: biological_process +def: "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes." [GOC:cab1, PMID:2181052] +synonym: "pumping behavior" RELATED [] +is_a: GO:0042755 ! eating behavior + +[Term] +id: GO:0043051 +name: regulation of pharyngeal pumping +namespace: biological_process +def: "Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes." [GOC:cab1, PMID:2181052] +is_a: GO:1903998 ! regulation of eating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043050 ! pharyngeal pumping +relationship: regulates GO:0043050 ! pharyngeal pumping + +[Term] +id: GO:0043052 +name: thermotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature." [GOC:cab1, WB_REF:cgc467] +synonym: "taxis in response to temperature stimulus" EXACT [] +xref: Wikipedia:Thermotaxis +is_a: GO:0009266 ! response to temperature stimulus +is_a: GO:0042330 ! taxis + +[Term] +id: GO:0043053 +name: dauer entry +namespace: biological_process +def: "Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development." [GOC:cab1, GOC:kmv, PMID:10077613] +synonym: "nematode entry into dormancy" EXACT [] +is_a: GO:0055115 ! entry into diapause +relationship: part_of GO:0040024 ! dauer larval development + +[Term] +id: GO:0043054 +name: dauer exit +namespace: biological_process +def: "Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development." [GOC:cab1, PMID:12620986] +synonym: "exit from nematode dormancy" EXACT [] +is_a: GO:0071981 ! exit from diapause +relationship: part_of GO:0040024 ! dauer larval development + +[Term] +id: GO:0043055 +name: maintenance of dauer +namespace: biological_process +def: "Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development." [GOC:cab1, WB_REF:wm2003ab740] +synonym: "maintenance of dormancy in the nematode" EXACT [] +is_a: GO:0071982 ! maintenance of diapause +relationship: part_of GO:0040024 ! dauer larval development + +[Term] +id: GO:0043056 +name: forward locomotion +namespace: biological_process +def: "Anterior movement of an organism, following the direction of the head of the animal." [GOC:go_curators] +is_a: GO:0033058 ! directional locomotion + +[Term] +id: GO:0043057 +name: backward locomotion +namespace: biological_process +def: "Posterior movement of an organism, e.g. following the direction of the tail of an animal." [GOC:go_curators] +is_a: GO:0033058 ! directional locomotion + +[Term] +id: GO:0043058 +name: regulation of backward locomotion +namespace: biological_process +def: "Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism." [GOC:go_curators] +is_a: GO:0040012 ! regulation of locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043057 ! backward locomotion +relationship: regulates GO:0043057 ! backward locomotion + +[Term] +id: GO:0043059 +name: regulation of forward locomotion +namespace: biological_process +def: "Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism." [GOC:go_curators] +is_a: GO:0040012 ! regulation of locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043056 ! forward locomotion +relationship: regulates GO:0043056 ! forward locomotion + +[Term] +id: GO:0043060 +name: meiotic metaphase I plate congression +namespace: biological_process +def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I." [GOC:cab1, PMID:10809666] +is_a: GO:0051311 ! meiotic metaphase plate congression +relationship: part_of GO:0045143 ! homologous chromosome segregation + +[Term] +id: GO:0043061 +name: meiotic metaphase II plate congression +namespace: biological_process +def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II." [GOC:cab1, PMID:10809666] +is_a: GO:0051311 ! meiotic metaphase plate congression +relationship: part_of GO:0045144 ! meiotic sister chromatid segregation + +[Term] +id: GO:0043062 +name: extracellular structure organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "extracellular structure organisation" EXACT [] +synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0043063 +name: intercellular bridge organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another." [GOC:jid] +synonym: "intercellular bridge organisation" EXACT [] +synonym: "intercellular bridge organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0043062 ! extracellular structure organization + +[Term] +id: GO:0043064 +name: obsolete flagellum organization +namespace: biological_process +def: "OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement." [GOC:curators, ISBN:0815316194] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "flagellum organisation" EXACT [] +synonym: "flagellum organization" EXACT [] +synonym: "flagellum organization and biogenesis" RELATED [GOC:mah] +is_obsolete: true +consider: GO:0044781 +consider: GO:0044782 + +[Term] +id: GO:0043065 +name: positive regulation of apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] +comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. +subset: goslim_chembl +synonym: "activation of apoptosis" NARROW [] +synonym: "positive regulation of apoptosis" NARROW [] +synonym: "pro-apoptosis" RELATED [] +synonym: "stimulation of apoptosis" NARROW [] +synonym: "up regulation of apoptosis" EXACT [] +synonym: "up-regulation of apoptosis" EXACT [] +synonym: "upregulation of apoptosis" EXACT [] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:0043068 ! positive regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006915 ! apoptotic process +relationship: positively_regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0043066 +name: negative regulation of apoptotic process +namespace: biological_process +alt_id: GO:0006916 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] +comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. +synonym: "anti-apoptosis" EXACT [] +synonym: "apoptosis inhibitor activity" RELATED [] +synonym: "down regulation of apoptosis" EXACT [] +synonym: "down-regulation of apoptosis" EXACT [] +synonym: "downregulation of apoptosis" EXACT [] +synonym: "inhibition of apoptosis" NARROW [] +synonym: "negative regulation of apoptosis" NARROW [] +synonym: "pro-survival" RELATED [] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:0043069 ! negative regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006915 ! apoptotic process +relationship: negatively_regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0043067 +name: regulation of programmed cell death +namespace: biological_process +alt_id: GO:0043070 +def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] +synonym: "regulation of non-apoptotic programmed cell death" NARROW [] +is_a: GO:0010941 ! regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0012501 ! programmed cell death +relationship: regulates GO:0012501 ! programmed cell death + +[Term] +id: GO:0043068 +name: positive regulation of programmed cell death +namespace: biological_process +alt_id: GO:0043071 +def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] +synonym: "activation of programmed cell death" NARROW [] +synonym: "positive regulation of non-apoptotic programmed cell death" NARROW [] +synonym: "stimulation of programmed cell death" NARROW [] +synonym: "up regulation of programmed cell death" EXACT [] +synonym: "up-regulation of programmed cell death" EXACT [] +synonym: "upregulation of programmed cell death" EXACT [] +is_a: GO:0010942 ! positive regulation of cell death +is_a: GO:0043067 ! regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0012501 ! programmed cell death +relationship: positively_regulates GO:0012501 ! programmed cell death + +[Term] +id: GO:0043069 +name: negative regulation of programmed cell death +namespace: biological_process +alt_id: GO:0043072 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] +synonym: "down regulation of programmed cell death" EXACT [] +synonym: "down-regulation of programmed cell death" EXACT [] +synonym: "downregulation of programmed cell death" EXACT [] +synonym: "inhibition of programmed cell death" NARROW [] +synonym: "negative regulation of non-apoptotic programmed cell death" NARROW [] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:0060548 ! negative regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0012501 ! programmed cell death +relationship: negatively_regulates GO:0012501 ! programmed cell death + +[Term] +id: GO:0043073 +name: germ cell nucleus +namespace: cellular_component +def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators] +synonym: "germ-cell nucleus" EXACT [] +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0043075 +name: obsolete sperm cell nucleus (sensu Magnoliophyta) +namespace: cellular_component +def: "OBSOLETE. The nucleus of a plant pollen cell, the male gamete, and its descendents." [GOC:jl] +comment: This term was made obsolete because the definition was incorrect. +synonym: "pollen germ cell nucleus" EXACT [] +synonym: "pollen germ-cell nucleus" EXACT [] +synonym: "sperm cell nucleus (sensu Magnoliophyta)" EXACT [] +is_obsolete: true +consider: GO:0048555 + +[Term] +id: GO:0043076 +name: megasporocyte nucleus +namespace: cellular_component +def: "The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents." [GOC:jl, ISBN:0618254153] +synonym: "megaspore mother cell nucleus" EXACT [] +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0043077 +name: initiation of acetate catabolic process +namespace: biological_process +def: "The activation of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:jl] +synonym: "initiation of acetate breakdown" EXACT [] +synonym: "initiation of acetate catabolism" EXACT [] +synonym: "initiation of acetate degradation" EXACT [] +is_a: GO:0045754 ! positive regulation of acetate catabolic process + +[Term] +id: GO:0043078 +name: polar nucleus +namespace: cellular_component +def: "Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus." [ISBN:0618254153] +is_a: GO:0043076 ! megasporocyte nucleus + +[Term] +id: GO:0043079 +name: antipodal cell nucleus +namespace: cellular_component +def: "The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents." [CL:0000537, GOC:jl] +is_a: GO:0043076 ! megasporocyte nucleus + +[Term] +id: GO:0043082 +name: megagametophyte egg cell nucleus +namespace: cellular_component +def: "The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo." [GOC:jl, GOC:mtg_sensu] +is_a: GO:0043076 ! megasporocyte nucleus + +[Term] +id: GO:0043083 +name: synaptic cleft +namespace: cellular_component +def: "The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released." [GOC:jl, http://synapses.mcg.edu/anatomy/chemical/synapse.stm] +subset: goslim_synapse +xref: NIF_Subcellular:sao243541954 +is_a: GO:0005576 ! extracellular region +relationship: part_of GO:0045202 ! synapse + +[Term] +id: GO:0043084 +name: penile erection +namespace: biological_process +def: "The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:jl, Wikipedia:Penile_erection] +xref: Wikipedia:Erection#Penile_erection +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007620 ! copulation + +[Term] +id: GO:0043085 +name: positive regulation of catalytic activity +namespace: biological_process +alt_id: GO:0048554 +def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] +subset: goslim_chembl +synonym: "activation of enzyme activity" NARROW [] +synonym: "activation of metalloenzyme activity" NARROW [] +synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] +synonym: "positive regulation of metalloenzyme activity" NARROW [] +synonym: "stimulation of enzyme activity" NARROW [] +synonym: "stimulation of metalloenzyme activity" NARROW [] +synonym: "up regulation of enzyme activity" EXACT [] +synonym: "up regulation of metalloenzyme activity" NARROW [] +synonym: "up-regulation of enzyme activity" EXACT [] +synonym: "up-regulation of metalloenzyme activity" NARROW [] +synonym: "upregulation of enzyme activity" EXACT [] +synonym: "upregulation of metalloenzyme activity" NARROW [] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003824 ! catalytic activity +relationship: positively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0043086 +name: negative regulation of catalytic activity +namespace: biological_process +alt_id: GO:0048553 +def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] +synonym: "down regulation of enzyme activity" EXACT [] +synonym: "down regulation of metalloenzyme activity" NARROW [] +synonym: "down-regulation of enzyme activity" EXACT [] +synonym: "down-regulation of metalloenzyme activity" EXACT [] +synonym: "downregulation of enzyme activity" EXACT [] +synonym: "downregulation of metalloenzyme activity" NARROW [] +synonym: "inhibition of enzyme activity" NARROW [] +synonym: "inhibition of metalloenzyme activity" NARROW [] +synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] +synonym: "negative regulation of metalloenzyme activity" NARROW [] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003824 ! catalytic activity +relationship: negatively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0043087 +name: regulation of GTPase activity +namespace: biological_process +alt_id: GO:0032312 +alt_id: GO:0032313 +alt_id: GO:0032314 +alt_id: GO:0032315 +alt_id: GO:0032316 +alt_id: GO:0032317 +alt_id: GO:0032318 +alt_id: GO:0032319 +alt_id: GO:0043088 +def: "Any process that modulates the rate of GTP hydrolysis by a GTPase." [GOC:jl, GOC:mah] +synonym: "regulation of ARF GTPase activity" NARROW [] +synonym: "regulation of Cdc42 GTPase activity" NARROW [] +synonym: "regulation of Rab GTPase activity" NARROW [] +synonym: "regulation of Rac GTPase activity" NARROW [] +synonym: "regulation of Ral GTPase activity" NARROW [] +synonym: "regulation of Ran GTPase activity" NARROW [] +synonym: "regulation of Rap GTPase activity" NARROW [] +synonym: "regulation of Ras GTPase activity" NARROW [] +synonym: "regulation of Rho GTPase activity" NARROW [] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003924 ! GTPase activity +relationship: regulates GO:0003924 ! GTPase activity + +[Term] +id: GO:0043090 +name: amino acid import +namespace: biological_process +def: "The directed movement of amino acids into a cell or organelle." [GOC:jl] +synonym: "amino acid uptake" EXACT [] +is_a: GO:0006865 ! amino acid transport + +[Term] +id: GO:0043093 +name: FtsZ-dependent cytokinesis +namespace: biological_process +def: "A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells." [GOC:mah, ISBN:0815108893, PMID:12626683] +comment: Note that this term is intended for the annotation of prokaryotic gene products. +synonym: "cytokinesis by binary fission" RELATED [GOC:dph] +synonym: "prokaryote-type cytokinesis" RELATED [GOC:mah] +synonym: "prokaryotic fission" RELATED [Wikipedia:Binary_fission] +xref: Wikipedia:Binary_fission +is_a: GO:0000910 ! cytokinesis +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0019954 ! asexual reproduction +relationship: part_of GO:0032505 ! reproduction of a single-celled organism +property_value: RO:0002161 NCBITaxon:2759 + +[Term] +id: GO:0043094 +name: cellular metabolic compound salvage +namespace: biological_process +def: "Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells." [GOC:mlg] +subset: goslim_pir +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0043095 +name: regulation of GTP cyclohydrolase I activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme GTP cyclohydrolase I." [GOC:jl] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003934 ! GTP cyclohydrolase I activity +relationship: regulates GO:0003934 ! GTP cyclohydrolase I activity + +[Term] +id: GO:0043096 +name: purine nucleobase salvage +namespace: biological_process +def: "Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis." [GOC:jl] +synonym: "purine base salvage" EXACT [GOC:go_curators] +is_a: GO:0009113 ! purine nucleobase biosynthetic process +is_a: GO:0043101 ! purine-containing compound salvage + +[Term] +id: GO:0043097 +name: pyrimidine nucleoside salvage +namespace: biological_process +def: "Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0008655 ! pyrimidine-containing compound salvage +is_a: GO:0043174 ! nucleoside salvage +is_a: GO:0046134 ! pyrimidine nucleoside biosynthetic process + +[Term] +id: GO:0043098 +name: purine deoxyribonucleoside salvage +namespace: biological_process +def: "Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0043101 ! purine-containing compound salvage +is_a: GO:0043174 ! nucleoside salvage +is_a: GO:0046123 ! purine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0043099 +name: pyrimidine deoxyribonucleoside salvage +namespace: biological_process +def: "Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0043097 ! pyrimidine nucleoside salvage +is_a: GO:0046126 ! pyrimidine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0043100 +name: pyrimidine nucleobase salvage +namespace: biological_process +def: "Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis." [GOC:jl] +synonym: "pyrimidine base salvage" EXACT [GOC:go_curators] +is_a: GO:0008655 ! pyrimidine-containing compound salvage + +[Term] +id: GO:0043101 +name: purine-containing compound salvage +namespace: biological_process +def: "Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis." [GOC:jl] +subset: goslim_pir +synonym: "purine salvage" RELATED [] +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage +is_a: GO:0072522 ! purine-containing compound biosynthetic process + +[Term] +id: GO:0043102 +name: amino acid salvage +namespace: biological_process +def: "Any process which produces an amino acid from derivatives of it, without de novo synthesis." [GOC:jl] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0043103 +name: hypoxanthine salvage +namespace: biological_process +def: "Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis." [GOC:jl, ISBN:0198506732] +synonym: "adenine, hypoxanthine and their nucleoside salvage" NARROW [] +synonym: "guanine, xanthine and their nucleoside salvage" NARROW [] +is_a: GO:0043096 ! purine nucleobase salvage +is_a: GO:0046101 ! hypoxanthine biosynthetic process + +[Term] +id: GO:0043104 +name: positive regulation of GTP cyclohydrolase I activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I." [GOC:jl] +synonym: "activation of GTP cyclohydrolase I activity" NARROW [] +synonym: "stimulation of GTP cyclohydrolase I activity" NARROW [] +synonym: "up regulation of GTP cyclohydrolase I activity" EXACT [] +synonym: "up-regulation of GTP cyclohydrolase I activity" EXACT [] +synonym: "upregulation of GTP cyclohydrolase I activity" EXACT [] +is_a: GO:0043095 ! regulation of GTP cyclohydrolase I activity +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003934 ! GTP cyclohydrolase I activity +relationship: positively_regulates GO:0003934 ! GTP cyclohydrolase I activity + +[Term] +id: GO:0043105 +name: negative regulation of GTP cyclohydrolase I activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I." [GOC:jl] +synonym: "down regulation of GTP cyclohydrolase I activity" EXACT [] +synonym: "down-regulation of GTP cyclohydrolase I activity" EXACT [] +synonym: "downregulation of GTP cyclohydrolase I activity" EXACT [] +synonym: "inhibition of GTP cyclohydrolase I activity" NARROW [] +is_a: GO:0043095 ! regulation of GTP cyclohydrolase I activity +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003934 ! GTP cyclohydrolase I activity +relationship: negatively_regulates GO:0003934 ! GTP cyclohydrolase I activity + +[Term] +id: GO:0043107 +name: type IV pilus-dependent motility +namespace: biological_process +def: "Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility." [GOC:go_curators, PMID:12704238] +synonym: "social gliding motility" NARROW [] +synonym: "TFP-dependent motility" EXACT [] +synonym: "TFP-dependent movement" EXACT [] +synonym: "twitching motility" NARROW [] +synonym: "type 4 pilus-dependent motility" EXACT [] +synonym: "type four pilus-dependent motility" EXACT [] +is_a: GO:0048870 ! cell motility + +[Term] +id: GO:0043108 +name: pilus retraction +namespace: biological_process +def: "The process of withdrawing a pilus back into a cell." [GOC:go_curators, PMID:17355871] +is_a: GO:0043711 ! pilus organization + +[Term] +id: GO:0043110 +name: rDNA spacer replication fork barrier binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription." [GOC:jl, GOC:mah, PMID:14645529] +synonym: "RFB binding" EXACT [] +is_a: GO:0000182 ! rDNA binding +is_a: GO:0031634 ! replication fork barrier binding + +[Term] +id: GO:0043111 +name: replication fork arrest +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected." [GOC:jl, GOC:pr, PMID:14645529] +comment: See also the biological process term 'site-specific replication termination ; GO:0071170' and its children. +synonym: "negative regulation of DNA replication at replication fork barrier" EXACT [GOC:dph, GOC:tb] +synonym: "replication fork blocking" EXACT [] +synonym: "replication fork stalling" EXACT [] +is_a: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication + +[Term] +id: GO:0043112 +name: receptor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:jl] +synonym: "receptor metabolism" EXACT [] +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0043113 +name: receptor clustering +namespace: biological_process +def: "The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response." [GOC:bf, GOC:jl, GOC:pr, PMID:19747931, PMID:21453460] +is_a: GO:0051668 ! localization within membrane +is_a: GO:0072657 ! protein localization to membrane +relationship: occurs_in GO:0005886 ! plasma membrane + +[Term] +id: GO:0043114 +name: regulation of vascular permeability +namespace: biological_process +def: "Any process that modulates the extent to which blood vessels can be pervaded by fluid." [GOC:jl] +is_a: GO:0003018 ! vascular process in circulatory system +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0008015 ! blood circulation + +[Term] +id: GO:0043115 +name: precorrin-2 dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin." [EC:1.3.1.76, RHEA:15613] +synonym: "1,3-dimethyluroporphyrinogen III dehydrogenase activity" EXACT [] +synonym: "CysG" RELATED [EC:1.3.1.76] +synonym: "dihydrosirohydrochlorin dehydrogenase activity" EXACT [] +synonym: "Met8p" RELATED [EC:1.3.1.76] +synonym: "precorrin-2 oxidase activity" EXACT [EC:1.3.1.76] +synonym: "precorrin-2:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.76] +synonym: "SirC" RELATED [EC:1.3.1.76] +synonym: "siroheme synthase activity" BROAD [] +xref: EC:1.3.1.76 +xref: KEGG_REACTION:R03947 +xref: MetaCyc:DIMETHUROPORDEHYDROG-RXN +xref: RHEA:15613 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043116 +name: negative regulation of vascular permeability +namespace: biological_process +def: "Any process that reduces the extent to which blood vessels can be pervaded by fluid." [GOC:jl] +synonym: "down regulation of vascular permeability" EXACT [] +synonym: "down-regulation of vascular permeability" EXACT [] +synonym: "downregulation of vascular permeability" EXACT [] +synonym: "inhibition of vascular permeability" NARROW [] +is_a: GO:0043114 ! regulation of vascular permeability + +[Term] +id: GO:0043117 +name: positive regulation of vascular permeability +namespace: biological_process +def: "Any process that increases the extent to which blood vessels can be pervaded by fluid." [GOC:jl] +synonym: "activation of vascular permeability" NARROW [] +synonym: "stimulation of vascular permeability" NARROW [] +synonym: "up regulation of vascular permeability" EXACT [] +synonym: "up-regulation of vascular permeability" EXACT [] +synonym: "upregulation of vascular permeability" EXACT [] +is_a: GO:0043114 ! regulation of vascular permeability + +[Term] +id: GO:0043120 +name: tumor necrosis factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages." [GOC:jl, http://lookwayup.com/] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0043121 +name: neurotrophin binding +namespace: molecular_function +alt_id: GO:0048404 +alt_id: GO:0048405 +def: "Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth." [GOC:jl, http://www.mercksource.com/, PR:000021998] +comment: Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858]. +synonym: "neurotrophic factor binding" EXACT [GOC:aruk, GOC:bc] +synonym: "neurotrophin 3 binding" NARROW [] +synonym: "neurotrophin 4/5 binding" NARROW [] +synonym: "neurotrophin TRK receptor activity" RELATED [] +synonym: "neurotrophin TRKA receptor activity" RELATED [] +synonym: "neurotrophin TRKB receptor activity" RELATED [] +synonym: "neurotrophin TRKC receptor activity" RELATED [] +synonym: "neurotrophin-3 binding" NARROW [] +synonym: "neurotrophin-4/5 binding" NARROW [] +synonym: "NT 4/5 binding" NARROW [] +synonym: "NT-3 binding" NARROW [] +synonym: "NT-4 binding" NARROW [] +synonym: "NT-4/5 binding" NARROW [] +synonym: "NT-5 binding" NARROW [] +synonym: "NT3 binding" NARROW [] +synonym: "NT4 binding" NARROW [] +synonym: "NT5 binding" NARROW [] +is_a: GO:0019838 ! growth factor binding + +[Term] +id: GO:0043122 +name: regulation of I-kappaB kinase/NF-kappaB signaling +namespace: biological_process +def: "Any process that modulates I-kappaB kinase/NF-kappaB signaling." [GOC:jl, PMID:12773372] +synonym: "regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [GOC:signaling] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling +relationship: regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling + +[Term] +id: GO:0043123 +name: positive regulation of I-kappaB kinase/NF-kappaB signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling." [GOC:jl] +synonym: "activation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "positive regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "stimulation of I-kappaB kinase/NF-kappaB cascade" NARROW [] +synonym: "up regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "up-regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "upregulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +is_a: GO:0043122 ! regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling +relationship: positively_regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling + +[Term] +id: GO:0043124 +name: negative regulation of I-kappaB kinase/NF-kappaB signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling." [GOC:jl] +synonym: "down regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "down-regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "downregulation of I-kappaB kinase/NF-kappaB cascade" RELATED [] +synonym: "inhibition of I-kappaB kinase/NF-kappaB cascade" NARROW [] +synonym: "negative regulation of I-kappaB kinase/NF-kappaB cascade" RELATED [GOC:signaling] +is_a: GO:0043122 ! regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling +relationship: negatively_regulates GO:0007249 ! I-kappaB kinase/NF-kappaB signaling + +[Term] +id: GO:0043125 +name: ErbB-3 class receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-3/HER3." [GOC:jl] +synonym: "HER3 receptor binding" EXACT [] +synonym: "Neu/ErbB-2 receptor activity" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0043126 +name: regulation of 1-phosphatidylinositol 4-kinase activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase." [GOC:jl] +synonym: "regulation of PI4K activity" EXACT [] +is_a: GO:0043550 ! regulation of lipid kinase activity +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity +relationship: regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity + +[Term] +id: GO:0043127 +name: negative regulation of 1-phosphatidylinositol 4-kinase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase." [GOC:jl] +synonym: "down regulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +synonym: "down-regulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +synonym: "downregulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +synonym: "inhibition of 1-phosphatidylinositol 4-kinase activity" NARROW [] +synonym: "negative regulation of PI4K activity" EXACT [] +is_a: GO:0043126 ! regulation of 1-phosphatidylinositol 4-kinase activity +is_a: GO:0090219 ! negative regulation of lipid kinase activity +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity +relationship: negatively_regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity + +[Term] +id: GO:0043128 +name: positive regulation of 1-phosphatidylinositol 4-kinase activity +namespace: biological_process +def: "Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase." [GOC:jl] +synonym: "activation of 1-phosphatidylinositol 4-kinase activity" NARROW [] +synonym: "positive regulation of PI4K activity" EXACT [] +synonym: "stimulation of 1-phosphatidylinositol 4-kinase activity" NARROW [] +synonym: "up regulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +synonym: "up-regulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +synonym: "upregulation of 1-phosphatidylinositol 4-kinase activity" EXACT [] +is_a: GO:0043126 ! regulation of 1-phosphatidylinositol 4-kinase activity +is_a: GO:0090218 ! positive regulation of lipid kinase activity +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity +relationship: positively_regulates GO:0004430 ! 1-phosphatidylinositol 4-kinase activity + +[Term] +id: GO:0043129 +name: surfactant homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli." [PMID:9751757] +is_a: GO:0048875 ! chemical homeostasis within a tissue + +[Term] +id: GO:0043130 +name: ubiquitin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation." [GOC:ecd] +xref: Reactome:R-HSA-1169404 "Transfer of ISG15 from E1 to E2 (UBCH8)" +xref: Reactome:R-HSA-205008 "Polyubiquitinated NRIF binds to p62 (Sequestosome)" +xref: Reactome:R-HSA-983152 "Transfer of ubiquitin from E1 to E2" +is_a: GO:0032182 ! ubiquitin-like protein binding + +[Term] +id: GO:0043131 +name: erythrocyte enucleation +namespace: biological_process +def: "The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation." [GOC:hjd] +is_a: GO:0090601 ! enucleation +relationship: part_of GO:0043354 ! enucleate erythrocyte maturation + +[Term] +id: GO:0043132 +name: NAD transport +namespace: biological_process +def: "The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:jl] +synonym: "NAD (oxidized) transport" EXACT [] +synonym: "NAD (reduced) transport" EXACT [] +synonym: "NADH transport" EXACT [] +synonym: "nicotinamide adenine dinucleotide transport" EXACT [] +synonym: "oxidized NAD transport" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide transport" EXACT [] +synonym: "reduced NAD transport" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide transport" EXACT [] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:0051182 ! coenzyme transport + +[Term] +id: GO:0043133 +name: hindgut contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046] +is_a: GO:0006939 ! smooth muscle contraction +is_a: GO:0022600 ! digestive system process + +[Term] +id: GO:0043134 +name: regulation of hindgut contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046] +is_a: GO:0006940 ! regulation of smooth muscle contraction +is_a: GO:0044058 ! regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043133 ! hindgut contraction +relationship: regulates GO:0043133 ! hindgut contraction + +[Term] +id: GO:0043135 +name: 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+." [MetaCyc:RXN-10969, PMID:12370170] +synonym: "PRPP pyrophosphatase activity" EXACT [] +xref: MetaCyc:RXN-10969 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0043136 +name: glycerol-3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate." [GOC:jl] +xref: MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN +xref: Reactome:R-HSA-8955794 "PGP:Mg2+ dimer hydrolyses 3PG to glycerol" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0043137 +name: DNA replication, removal of RNA primer +namespace: biological_process +def: "Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease." [GOC:jl, PMID:12424238] +synonym: "Okazaki initiator RNA removal" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0006401 ! RNA catabolic process + +[Term] +id: GO:0043138 +name: 3'-5' DNA helicase activity +namespace: molecular_function +alt_id: GO:0043140 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'." [GOC:jl] +synonym: "3' to 5' DNA helicase activity" EXACT [] +synonym: "ATP-dependent 3' to 5' DNA helicase activity" EXACT [] +synonym: "ATP-dependent 3'-5' DNA helicase activity" EXACT [] +is_a: GO:0003678 ! DNA helicase activity + +[Term] +id: GO:0043139 +name: 5'-3' DNA helicase activity +namespace: molecular_function +alt_id: GO:0008722 +alt_id: GO:0043141 +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'." [GOC:jl] +synonym: "5' to 3' DNA helicase activity" EXACT [] +synonym: "ATP-dependent 5' to 3' DNA helicase activity" EXACT [] +synonym: "ATP-dependent 5'-3' DNA helicase activity" EXACT [] +synonym: "DNA helicase IV activity" NARROW [] +is_a: GO:0003678 ! DNA helicase activity + +[Term] +id: GO:0043143 +name: regulation of translation by machinery localization +namespace: biological_process +def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] +synonym: "establishment and maintenance of translational machinery localization" EXACT [] +synonym: "establishment and maintenance of translational protein localization" EXACT [] +synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah] +synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb] +synonym: "translational protein localization" EXACT [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0034613 ! cellular protein localization +intersection_of: GO:0008104 ! protein localization +intersection_of: part_of GO:0006412 ! translation +relationship: part_of GO:0006412 ! translation + +[Term] +id: GO:0043144 +name: snoRNA processing +namespace: biological_process +def: "Any process involved in the conversion of a primary small nucleolar RNA (snoRNA) transcript into a mature snoRNA." [GOC:go_curators, PMID:12773397] +subset: goslim_yeast +is_a: GO:0016074 ! snoRNA metabolic process +is_a: GO:0034470 ! ncRNA processing + +[Term] +id: GO:0043145 +name: snoRNA 3'-end cleavage +namespace: biological_process +def: "The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional." [GOC:go_curators, PMID:12773397] +synonym: "snoRNA 3' end cleavage" EXACT [] +is_a: GO:0031126 ! snoRNA 3'-end processing +is_a: GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic + +[Term] +id: GO:0043149 +name: stress fiber assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity." [GOC:go_curators, GOC:mah, PMID:16651381] +synonym: "actin cable assembly" RELATED [GOC:mah] +synonym: "actin cable formation" RELATED [GOC:mah] +synonym: "stress fibre biosynthesis" RELATED [] +synonym: "stress fibre formation" RELATED [] +is_a: GO:0030038 ! contractile actin filament bundle assembly +is_a: GO:0031032 ! actomyosin structure organization + +[Term] +id: GO:0043150 +name: DNA synthesis involved in double-strand break repair via homologous recombination +namespace: biological_process +def: "The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination." [GOC:go_curators] +synonym: "DNA synthesis during double-strand break repair via homologous recombination" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:0000724 ! double-strand break repair via homologous recombination +relationship: part_of GO:0000724 ! double-strand break repair via homologous recombination + +[Term] +id: GO:0043151 +name: DNA synthesis involved in double-strand break repair via single-strand annealing +namespace: biological_process +def: "The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing." [GOC:go_curators] +synonym: "DNA synthesis during double-strand break repair via single-strand annealing" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:0045002 ! double-strand break repair via single-strand annealing +relationship: part_of GO:0045002 ! double-strand break repair via single-strand annealing + +[Term] +id: GO:0043152 +name: induction of bacterial agglutination +namespace: biological_process +def: "Any process in which infecting bacteria are clumped together by a host organism." [GOC:jl] +is_a: GO:0019731 ! antibacterial humoral response + +[Term] +id: GO:0043153 +name: entrainment of circadian clock by photoperiod +namespace: biological_process +def: "The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night)." [GOC:jl] +synonym: "photoentrainment of circadian clock" EXACT [PMID:10217146] +is_a: GO:0009648 ! photoperiodism +is_a: GO:0009649 ! entrainment of circadian clock + +[Term] +id: GO:0043154 +name: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +alt_id: GO:0001719 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process." [GOC:jl, GOC:mtg_apoptosis] +synonym: "down regulation of caspase activity" EXACT [] +synonym: "down-regulation of caspase activity" EXACT [] +synonym: "downregulation of caspase activity" EXACT [] +synonym: "inhibition of caspase activation" NARROW [] +synonym: "inhibition of caspase activity" NARROW [] +synonym: "negative regulation of caspase activation" EXACT [] +synonym: "negative regulation of caspase activity" BROAD [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:0043281 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:2000117 ! negative regulation of cysteine-type endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process +relationship: negatively_regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0043155 +name: negative regulation of photosynthesis, light reaction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis." [GOC:jl] +synonym: "down regulation of photosynthesis, light reaction" EXACT [] +synonym: "down-regulation of photosynthesis, light reaction" EXACT [] +synonym: "downregulation of photosynthesis, light reaction" EXACT [] +synonym: "inhibition of photosynthesis, light reaction" NARROW [] +is_a: GO:0042548 ! regulation of photosynthesis, light reaction +is_a: GO:1905156 ! negative regulation of photosynthesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019684 ! photosynthesis, light reaction +relationship: negatively_regulates GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0043156 +name: chromatin remodeling in response to cation stress +namespace: biological_process +def: "Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment." [GOC:jl, GOC:vw, PMID:14762213] +is_a: GO:0006338 ! chromatin remodeling +is_a: GO:0071473 ! cellular response to cation stress + +[Term] +id: GO:0043157 +name: response to cation stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment." [GOC:jl, PMID:14762213] +is_a: GO:0009651 ! response to salt stress + +[Term] +id: GO:0043158 +name: heterocyst differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen." [GOC:jl] +synonym: "heterocyst biosynthesis" EXACT [] +synonym: "heterocyst cell differentiation" EXACT [] +synonym: "heterocyst formation" EXACT [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0043159 +name: acrosomal matrix +namespace: cellular_component +def: "A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction." [GOC:jl, PMID:8949900, PMID:9139729] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0001669 ! acrosomal vesicle +relationship: part_of GO:0005773 ! vacuole + +[Term] +id: GO:0043160 +name: acrosomal lumen +namespace: cellular_component +def: "The volume enclosed within the acrosome membrane." [GOC:go_curators] +is_a: GO:0034774 ! secretory granule lumen +is_a: GO:0043202 ! lysosomal lumen +relationship: part_of GO:0001669 ! acrosomal vesicle + +[Term] +id: GO:0043161 +name: proteasome-mediated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:go_curators] +synonym: "proteasomal pathway" EXACT [] +synonym: "proteasomal processing" RELATED [] +synonym: "proteasomal ubiquitin-dependent protein breakdown" EXACT [] +synonym: "proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +synonym: "proteasomal ubiquitin-dependent protein catabolism" EXACT [] +synonym: "proteasomal ubiquitin-dependent protein degradation" EXACT [] +synonym: "proteasome pathway" RELATED [] +is_a: GO:0006511 ! ubiquitin-dependent protein catabolic process +is_a: GO:0010498 ! proteasomal protein catabolic process + +[Term] +id: GO:0043162 +name: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation." [GOC:jl, PMID:11511343] +synonym: "ubiquitin-dependent protein breakdown via the multivesicular body pathway" EXACT [] +synonym: "ubiquitin-dependent protein catabolic process via the MVB pathway" EXACT [] +synonym: "ubiquitin-dependent protein catabolism via the MVB pathway" EXACT [] +synonym: "ubiquitin-dependent protein degradation via the multivesicular body pathway" EXACT [] +is_a: GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: has_part GO:0007039 ! protein catabolic process in the vacuole +relationship: has_part GO:0071985 ! multivesicular body sorting pathway + +[Term] +id: GO:0043163 +name: cell envelope organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present." [GOC:jl] +subset: goslim_pir +synonym: "cell envelope organisation" EXACT [] +synonym: "cell envelope organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045229 ! external encapsulating structure organization + +[Term] +id: GO:0043164 +name: Gram-negative-bacterium-type cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane." [GOC:jl, GOC:mtg_sensu, ISBN:0815108893] +synonym: "1-2nm peptidoglycan-based cell wall biogenesis" EXACT [] +synonym: "cell wall anabolism" BROAD [] +synonym: "cell wall assembly" BROAD [] +synonym: "cell wall biosynthetic process" BROAD [] +synonym: "cell wall formation" BROAD [] +synonym: "cell wall synthesis" BROAD [] +is_a: GO:0009273 ! peptidoglycan-based cell wall biogenesis + +[Term] +id: GO:0043165 +name: Gram-negative-bacterium-type cell outer membrane assembly +namespace: biological_process +def: "The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures." [GOC:jl, ISBN:0135712254] +synonym: "cell outer membrane biogenesis" RELATED [GOC:mah] +is_a: GO:0071709 ! membrane assembly +relationship: part_of GO:0043163 ! cell envelope organization + +[Term] +id: GO:0043167 +name: ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms." [GOC:jl] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_yeast +synonym: "atom binding" RELATED [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0043168 +name: anion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] +is_a: GO:0043167 ! ion binding + +[Term] +id: GO:0043169 +name: cation binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge." [GOC:jl] +is_a: GO:0043167 ! ion binding + +[Term] +id: GO:0043170 +name: macromolecule metabolic process +namespace: biological_process +alt_id: GO:0043283 +alt_id: GO:0044259 +def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: goslim_pir +synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "macromolecule metabolism" EXACT [] +synonym: "multicellular organismal macromolecule metabolic process" NARROW [] +synonym: "organismal macromolecule metabolism" EXACT [] +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0043171 +name: peptide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl] +synonym: "peptide breakdown" EXACT [] +synonym: "peptide catabolism" EXACT [] +synonym: "peptide degradation" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0043172 +name: obsolete ferredoxin biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each." [GOC:jl, ISBN:0198506732] +comment: This term was made obsolete because it refers to biosynthesis of a protein. +synonym: "ferredoxin anabolism" EXACT [] +synonym: "ferredoxin biosynthesis" EXACT [] +synonym: "ferredoxin formation" EXACT [] +synonym: "ferredoxin synthesis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0043173 +name: nucleotide salvage +namespace: biological_process +def: "Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis." [GOC:jl] +xref: Wikipedia:Nucleotide_salvage +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0043174 +name: nucleoside salvage +namespace: biological_process +def: "Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis." [GOC:jl] +is_a: GO:0009163 ! nucleoside biosynthetic process +is_a: GO:0043094 ! cellular metabolic compound salvage + +[Term] +id: GO:0043175 +name: RNA polymerase core enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme." [GOC:jl, GOC:txnOH] +is_a: GO:0070063 ! RNA polymerase binding + +[Term] +id: GO:0043176 +name: amine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group." [GOC:jl] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0043177 +name: organic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage." [GOC:jl, ISBN:0198506732] +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0043178 +name: alcohol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group." [GOC:jl, ISBN:0198506732] +subset: goslim_pir +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0043179 +name: rhythmic excitation +namespace: biological_process +def: "Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit." [GOC:go_curators, ISBN:0195088433] +is_a: GO:0060024 ! rhythmic synaptic transmission + +[Term] +id: GO:0043180 +name: rhythmic inhibition +namespace: biological_process +def: "Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit." [GOC:go_curators] +is_a: GO:0060024 ! rhythmic synaptic transmission + +[Term] +id: GO:0043181 +name: vacuolar sequestering +namespace: biological_process +def: "The process of transporting a substance into, and confining within, a vacuole." [GOC:jl] +synonym: "retention in vacuole" EXACT [] +synonym: "sequestering in vacuole" EXACT [] +synonym: "sequestration in vacuole" EXACT [] +synonym: "storage in vacuole" EXACT [] +synonym: "vacuolar retention" EXACT [] +synonym: "vacuolar sequestration" EXACT [] +synonym: "vacuolar storage" EXACT [] +is_a: GO:0051651 ! maintenance of location in cell + +[Term] +id: GO:0043182 +name: vacuolar sequestering of sodium ion +namespace: biological_process +def: "The process of transporting sodium ions into, and confining within, a vacuole." [GOC:jl] +synonym: "sequestering of sodium ion (Na+) in vacuole" EXACT [] +synonym: "sequestration of sodium ion (Na+) in vacuole" EXACT [] +synonym: "sodium ion (Na+) retention in vacuole" EXACT [] +synonym: "sodium ion (Na+) storage in vacuole" EXACT [] +synonym: "vacuolar sequestering of sodium ion (Na+)" EXACT [] +synonym: "vacuolar sequestration of sodium ion (Na+)" EXACT [] +synonym: "vacuolar sodium ion (Na+) retention" EXACT [] +synonym: "vacuolar sodium ion (Na+) storage" EXACT [] +is_a: GO:0043181 ! vacuolar sequestering +relationship: part_of GO:0006883 ! cellular sodium ion homeostasis + +[Term] +id: GO:0043183 +name: vascular endothelial growth factor receptor 1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 1." [GOC:st] +synonym: "Flt-1 binding" EXACT [] +synonym: "VEGF receptor 1 binding" EXACT [] +synonym: "VEGFR 1 binding" EXACT [] +is_a: GO:0005172 ! vascular endothelial growth factor receptor binding + +[Term] +id: GO:0043184 +name: vascular endothelial growth factor receptor 2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2." [GOC:st] +synonym: "Flk-1 binding" EXACT [] +synonym: "KDR binding" BROAD [] +synonym: "kinase domain region binding" EXACT [] +synonym: "VEGF receptor 2 binding" EXACT [] +synonym: "VEGFR 2 binding" EXACT [] +is_a: GO:0005172 ! vascular endothelial growth factor receptor binding + +[Term] +id: GO:0043185 +name: vascular endothelial growth factor receptor 3 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 3." [GOC:st] +synonym: "fms-like-tyrosine kinase (Flt)-4 binding" EXACT [] +synonym: "VEGF receptor 3 binding" EXACT [] +synonym: "VEGFR 3 binding" EXACT [] +is_a: GO:0005172 ! vascular endothelial growth factor receptor binding + +[Term] +id: GO:0043186 +name: P granule +namespace: cellular_component +alt_id: GO:0018994 +def: "A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes." [GOC:dph, GOC:kmv, PMID:11262230] +synonym: "germline granule" EXACT [] +synonym: "nuage" BROAD [] +synonym: "polar granule" EXACT [] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +relationship: part_of GO:0060293 ! germ plasm + +[Term] +id: GO:0043187 +name: cell septum surface +namespace: cellular_component +def: "The extracellular (rather than the intracellular) exterior of a dividing septum; this surface is usually composed of cell wall material, for example, lineal (1,3)-beta-D-glucan in S. pombe." [GOC:go_curators] +synonym: "septum surface" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030428 ! cell septum + +[Term] +id: GO:0043188 +name: cell septum edging +namespace: cellular_component +def: "The cell wall material that surrounds the septum in fungal cells." [GOC:vw] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009277 ! fungal-type cell wall + +[Term] +id: GO:0043189 +name: H4/H2A histone acetyltransferase complex +namespace: cellular_component +def: "A multisubunit complex that catalyzes the acetylation of histones H4 and H2A." [GOC:mah, GOC:rb] +synonym: "H4/H2A HAT complex" EXACT [] +is_a: GO:1902562 ! H4 histone acetyltransferase complex + +[Term] +id: GO:0043190 +name: ATP-binding cassette (ABC) transporter complex +namespace: cellular_component +alt_id: GO:0043191 +alt_id: GO:0043192 +def: "A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter." [GOC:jl, GOC:mtg_sensu, PMID:11421269, PMID:15111107] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "ABC-type efflux permease complex" NARROW [] +synonym: "ABC-type efflux porter complex" NARROW [] +synonym: "ABC-type uptake permease complex" NARROW [] +synonym: "mating pheromone exporter" NARROW [] +is_a: GO:0098533 ! ATPase dependent transmembrane transport complex +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0043194 +name: axon initial segment +namespace: cellular_component +def: "Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment." [GOC:nln, GOC:sl, PMID:1754851, PMID:21551097] +synonym: "initial segment" EXACT [] +xref: NIF_Subcellular:sao256000789 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0043195 +name: terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc, GOC:nln, PMID:10218156, PMID:8409967] +synonym: "bouton" EXACT [] +synonym: "presynaptic bouton" EXACT [] +synonym: "synaptic bouton" EXACT [NIF_Subcellular:sao187426937] +synonym: "terminal button" EXACT [] +xref: NIF_Subcellular:sao187426937 +is_a: GO:0098793 ! presynapse +relationship: part_of GO:0043679 ! axon terminus + +[Term] +id: GO:0043196 +name: varicosity +namespace: cellular_component +def: "Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters." [GOC:nln] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon + +[Term] +id: GO:0043197 +name: dendritic spine +namespace: cellular_component +def: "A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity." [GOC:nln] +subset: goslim_synapse +synonym: "branched dendritic spine" NARROW [NIF_Subcellular:sao965204139] +synonym: "dendrite spine" EXACT [] +synonym: "mushroom dendritic spine" NARROW [NIF_Subcellular:sao876577163] +synonym: "sessile dendritic spine" NARROW [NIF_Subcellular:sao1536532595] +synonym: "stubby dendritic spine" NARROW [NIF_Subcellular:sao317384566] +synonym: "thin dendritic spine" NARROW [NIF_Subcellular:sao1232858786] +xref: NIF_Subcellular:sao1799103720 +xref: Wikipedia:Dendritic_spine +is_a: GO:0044309 ! neuron spine +is_a: GO:0098794 ! postsynapse +relationship: part_of GO:0030425 ! dendrite + +[Term] +id: GO:0043198 +name: dendritic shaft +namespace: cellular_component +def: "Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines." [GOC:nln] +synonym: "trunk" RELATED [NIF_Subcellular:sao1078172392] +xref: NIF_Subcellular:sao2034472720 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030425 ! dendrite + +[Term] +id: GO:0043199 +name: sulfate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sulfate, SO4(2-), a negatively charged small molecule." [GOC:mlg] +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043200 +name: response to amino acid +namespace: biological_process +alt_id: GO:0010237 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] +synonym: "response to amino acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0043201 +name: response to leucine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus." [GOC:mlg] +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0043202 +name: lysosomal lumen +namespace: cellular_component +def: "The volume enclosed within the lysosomal membrane." [GOC:jl, PMID:15213228] +is_a: GO:0005775 ! vacuolar lumen +relationship: part_of GO:0005764 ! lysosome + +[Term] +id: GO:0043203 +name: axon hillock +namespace: cellular_component +def: "Portion of the neuronal cell soma from which the axon originates." [GOC:nln] +xref: NIF_Subcellular:sao627227260 +xref: Wikipedia:Axon_hillock +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +relationship: part_of GO:0043025 ! neuronal cell body + +[Term] +id: GO:0043204 +name: perikaryon +namespace: cellular_component +def: "The portion of the cell soma (neuronal cell body) that excludes the nucleus." [GOC:jl] +synonym: "cell soma cytoplasm" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043025 ! neuronal cell body + +[Term] +id: GO:0043207 +name: response to external biotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0009607 ! response to biotic stimulus + +[Term] +id: GO:0043208 +name: glycosphingolipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide." [GOC:jl] +is_a: GO:0046625 ! sphingolipid binding +is_a: GO:0051861 ! glycolipid binding + +[Term] +id: GO:0043209 +name: myelin sheath +namespace: cellular_component +def: "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system." [GOC:cjm, GOC:jl, NIF_Subcellular:sao593830697, Wikipedia:Myelin] +synonym: "astrocyte sheath" NARROW [NIF_Subcellular:nlx_subcell_20090204] +synonym: "oligodendrocyte myelin sheath" NARROW [NIF_Subcellular:sao1279474730] +synonym: "Schwann cell myelin sheath" NARROW [] +xref: FMA:62983 +xref: NIF_Subcellular:sao593830697 +xref: Wikipedia:Myelin +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0043210 +name: alkanesulfonate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group." [GOC:mlg] +is_a: GO:0043168 ! anion binding +is_a: GO:0043177 ! organic acid binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043211 +name: ATPase-coupled carbohydrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane." [GOC:mlg] +synonym: "ATP-dependent carbohydrate transmembrane transporter activity" EXACT [] +synonym: "carbohydrate ABC transporter" NARROW [] +synonym: "carbohydrate-transporting ATPase activity" EXACT [] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0043212 +name: carbohydrate-exporting ATPase activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out)." [GOC:mlg] +is_a: GO:0043211 ! ATPase-coupled carbohydrate transmembrane transporter activity + +[Term] +id: GO:0043213 +name: bacteriocin transport +namespace: biological_process +def: "The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain." [GOC:mlg] +is_a: GO:0015833 ! peptide transport + +[Term] +id: GO:0043214 +name: ATPase-coupled bacteriocin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate." [GOC:mlg] +synonym: "bacteriocin ABC transporter" NARROW [] +is_a: GO:0015440 ! ATPase-coupled peptide transmembrane transporter activity +is_a: GO:0022885 ! bacteriocin transmembrane transporter activity + +[Term] +id: GO:0043215 +name: daunorubicin transport +namespace: biological_process +def: "The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, GOC:mlg, http://www.mercksource.com/] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015893 ! drug transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901656 ! glycoside transport + +[Term] +id: GO:0043216 +name: ATPase-coupled daunorubicin transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out)." [GOC:mlg] +synonym: "ATP-dependent daunorubicin transmembrane transporter activity" EXACT [] +synonym: "daunorubicin ABC transporter" NARROW [] +synonym: "daunorubicin-transporting ATPase activity" EXACT [] +xref: RHEA:33147 +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0043215 ! daunorubicin transport + +[Term] +id: GO:0043217 +name: myelin maintenance +namespace: biological_process +def: "The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath." [GOC:dgh] +is_a: GO:0007009 ! plasma membrane organization +relationship: part_of GO:0042552 ! myelination + +[Term] +id: GO:0043218 +name: compact myelin +namespace: cellular_component +def: "The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs." [GOC:dgh, NIF_Subcellular:sao1123256993] +synonym: "oligodendrocyte compact myelin" NARROW [NIF_Subcellular:sao1186642361] +synonym: "Schwann cell compact myelin" NARROW [] +xref: NIF_Subcellular:sao1123256993 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043209 ! myelin sheath + +[Term] +id: GO:0043219 +name: lateral loop +namespace: cellular_component +def: "Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode." [GOC:dgh] +synonym: "oligodendrocyte paranodal termination" RELATED [NIF_Subcellular:sao1354781919] +synonym: "paranodal loop" RELATED [NIF_Subcellular:sao1354781919] +synonym: "Schwann cell paranodal termination" RELATED [NIF_Subcellular:sao1067215520] +xref: NIF_Subcellular:sao1067215520 +xref: NIF_Subcellular:sao1354781919 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043209 ! myelin sheath + +[Term] +id: GO:0043220 +name: Schmidt-Lanterman incisure +namespace: cellular_component +alt_id: GO:0044287 +def: "Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier." [GOC:dgh] +synonym: "Schmidt-Lanterman cleft" EXACT [] +xref: NIF_Subcellular:sao254777664 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043218 ! compact myelin + +[Term] +id: GO:0043221 +name: SMC family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization." [GOC:jl, GOC:vw, InterPro:IPR024704, PMID:9640531] +synonym: "structural maintenance of chromosomes family protein binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0043223 +name: cytoplasmic SCF ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] +synonym: "cytoplasmic cullin complex" EXACT [] +synonym: "cytoplasmic SCF complex" EXACT [] +synonym: "cytoplasmic Skp1/Cul1/F-box protein complex" EXACT [] +is_a: GO:0000153 ! cytoplasmic ubiquitin ligase complex +is_a: GO:0019005 ! SCF ubiquitin ligase complex +intersection_of: GO:0019005 ! SCF ubiquitin ligase complex +intersection_of: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0043224 +name: nuclear SCF ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] +synonym: "nuclear cullin complex" EXACT [] +synonym: "nuclear SCF complex" EXACT [] +synonym: "nuclear Skp1/Cul1/F-box protein complex" EXACT [] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +is_a: GO:0019005 ! SCF ubiquitin ligase complex +intersection_of: GO:0019005 ! SCF ubiquitin ligase complex +intersection_of: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0043225 +name: ATPase-coupled inorganic anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in)." [GOC:mlg] +synonym: "anion ABC transporter" NARROW [] +synonym: "anion transmembrane-transporting ATPase activity" RELATED [] +synonym: "anion-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent anion transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled anion transmembrane transporter activity" EXACT [] +xref: Reactome:R-HSA-1454916 "The ABCC family mediates organic anion transport" +xref: Reactome:R-HSA-5690340 "Defective ABCC6 does not transport organic anion from cytosol to extracellular region" +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity + +[Term] +id: GO:0043226 +name: organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +xref: NIF_Subcellular:sao1539965131 +xref: Wikipedia:Organelle +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0043227 +name: membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] +synonym: "membrane-enclosed organelle" EXACT [] +xref: NIF_Subcellular:sao414196390 +is_a: GO:0043226 ! organelle + +[Term] +id: GO:0043228 +name: non-membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] +synonym: "non-membrane-enclosed organelle" EXACT [] +xref: NIF_Subcellular:sao1456184038 +is_a: GO:0043226 ! organelle + +[Term] +id: GO:0043229 +name: intracellular organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] +subset: goslim_pir +is_a: GO:0043226 ! organelle +intersection_of: GO:0043226 ! organelle +intersection_of: part_of GO:0005622 ! intracellular +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0043230 +name: extracellular organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] +subset: goslim_pir +is_a: GO:0043226 ! organelle +intersection_of: GO:0043226 ! organelle +intersection_of: part_of GO:0005576 ! extracellular region +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0043231 +name: intracellular membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] +subset: goslim_pir +synonym: "intracellular membrane-enclosed organelle" EXACT [] +is_a: GO:0043227 ! membrane-bounded organelle +is_a: GO:0043229 ! intracellular organelle + +[Term] +id: GO:0043232 +name: intracellular non-membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] +subset: goslim_mouse +subset: goslim_pir +synonym: "intracellular non-membrane-enclosed organelle" EXACT [] +is_a: GO:0043228 ! non-membrane-bounded organelle +is_a: GO:0043229 ! intracellular organelle +intersection_of: GO:0043228 ! non-membrane-bounded organelle +intersection_of: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0043233 +name: organelle lumen +namespace: cellular_component +def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah] +is_a: GO:0031974 ! membrane-enclosed lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0043226 ! organelle +relationship: part_of GO:0043226 ! organelle + +[Term] +id: GO:0043235 +name: receptor complex +namespace: cellular_component +def: "Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:go_curators] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0043236 +name: laminin binding +namespace: molecular_function +alt_id: GO:0043238 +alt_id: GO:0043239 +def: "Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells." [GOC:ecd] +synonym: "laminin-2 binding" NARROW [] +synonym: "laminin-4 binding" NARROW [] +is_a: GO:0005515 ! protein binding +is_a: GO:0050840 ! extracellular matrix binding +property_value: RO:0002161 NCBITaxon:4895 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0043237 +name: laminin-1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1." [GOC:go_curators] +synonym: "laminin-111 binding" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043236 ! laminin binding + +[Term] +id: GO:0043240 +name: Fanconi anaemia nuclear complex +namespace: cellular_component +def: "A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage." [GOC:jl, PMID:12093742] +synonym: "FA complex" EXACT [] +synonym: "FA core complex" EXACT [] +synonym: "FA nuclear complex" EXACT [] +synonym: "Fanconi anaemia complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm + +[Term] +id: GO:0043242 +name: negative regulation of protein-containing complex disassembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] +synonym: "down regulation of protein complex disassembly" EXACT [] +synonym: "down-regulation of protein complex disassembly" EXACT [] +synonym: "downregulation of protein complex disassembly" EXACT [] +synonym: "inhibition of protein complex disassembly" NARROW [] +synonym: "negative regulation of protein complex disassembly" RELATED [] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032984 ! protein-containing complex disassembly +relationship: negatively_regulates GO:0032984 ! protein-containing complex disassembly + +[Term] +id: GO:0043243 +name: positive regulation of protein-containing complex disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] +synonym: "activation of protein complex disassembly" NARROW [] +synonym: "positive regulation of protein complex disassembly" RELATED [] +synonym: "stimulation of protein complex disassembly" NARROW [] +synonym: "up regulation of protein complex disassembly" EXACT [] +synonym: "up-regulation of protein complex disassembly" EXACT [] +synonym: "upregulation of protein complex disassembly" EXACT [] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032984 ! protein-containing complex disassembly +relationship: positively_regulates GO:0032984 ! protein-containing complex disassembly + +[Term] +id: GO:0043244 +name: regulation of protein-containing complex disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] +synonym: "regulation of protein complex disassembly" RELATED [] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032984 ! protein-containing complex disassembly +relationship: regulates GO:0032984 ! protein-containing complex disassembly + +[Term] +id: GO:0043245 +name: extraorganismal space +namespace: cellular_component +def: "The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms." [GOC:jl] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0043246 +name: megasome +namespace: cellular_component +def: "Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex." [PMID:11206117, PMID:1999020] +is_a: GO:0005764 ! lysosome + +[Term] +id: GO:0043247 +name: telomere maintenance in response to DNA damage +namespace: biological_process +def: "Any process that occur in response to the presence of critically short or damaged telomeres." [GOC:BHF, GOC:BHF_telomere, GOC:jbu, PMID:15279784] +synonym: "DNA damage response, telomere maintenance" EXACT [] +is_a: GO:0000723 ! telomere maintenance +is_a: GO:0006974 ! cellular response to DNA damage stimulus + +[Term] +id: GO:0043248 +name: proteasome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a mature, active proteasome complex." [GOC:go_curators, PMID:10872471] +synonym: "26S proteasome assembly" NARROW [] +synonym: "proteasome complex assembly" EXACT [] +synonym: "proteasome maturation" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0043249 +name: erythrocyte maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl] +synonym: "RBC maturation" EXACT [CL:0000232] +synonym: "red blood cell maturation" EXACT [CL:0000232] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0048821 ! erythrocyte development + +[Term] +id: GO:0043250 +name: sodium-dependent organic anion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner." [GOC:go_curators] +is_a: GO:0008514 ! organic anion transmembrane transporter activity + +[Term] +id: GO:0043251 +name: sodium-dependent organic anion transport +namespace: biological_process +def: "The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015711 ! organic anion transport + +[Term] +id: GO:0043252 +name: sodium-independent organic anion transport +namespace: biological_process +def: "The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:go_curators] +is_a: GO:0015711 ! organic anion transport + +[Term] +id: GO:0043253 +name: chloroplast ribosome +namespace: cellular_component +def: "A ribosome contained within a chloroplast." [GOC:ecd] +is_a: GO:0009547 ! plastid ribosome +intersection_of: GO:0005840 ! ribosome +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009570 ! chloroplast stroma + +[Term] +id: GO:0043254 +name: regulation of protein-containing complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] +synonym: "regulation of protein complex assembly" RELATED [] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0065003 ! protein-containing complex assembly +relationship: regulates GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0043255 +name: regulation of carbohydrate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl] +synonym: "regulation of carbohydrate anabolism" EXACT [] +synonym: "regulation of carbohydrate biosynthesis" EXACT [] +synonym: "regulation of carbohydrate formation" EXACT [] +synonym: "regulation of carbohydrate synthesis" EXACT [] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0009889 ! regulation of biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016051 ! carbohydrate biosynthetic process +relationship: regulates GO:0016051 ! carbohydrate biosynthetic process + +[Term] +id: GO:0043256 +name: laminin complex +namespace: cellular_component +def: "A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes." [GOC:jl, http://www.sdbonline.org/fly/newgene/laminna1.htm, PMID:10842354] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005604 ! basement membrane +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0043257 +name: laminin-8 complex +namespace: cellular_component +def: "A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-411 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0043258 +name: laminin-9 complex +namespace: cellular_component +def: "A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-421 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0043259 +name: laminin-10 complex +namespace: cellular_component +def: "A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-511 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0043260 +name: laminin-11 complex +namespace: cellular_component +def: "A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-521 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0043261 +name: laminin-12 complex +namespace: cellular_component +def: "A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains." [GOC:jl, PMID:10842354] +synonym: "laminin-213 complex" EXACT [GOC:dph, PMID:15979864] +is_a: GO:0043256 ! laminin complex + +[Term] +id: GO:0043262 +name: adenosine-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + H2O = AMP + phosphate." [EC:3.6.1.5, PMID:1470606] +synonym: "adenosine diphosphatase activity" EXACT [] +synonym: "ADPase" BROAD [EC:3.6.1.5] +synonym: "ADPase activity" EXACT [EC:3.6.1.5] +synonym: "ATP diphosphohydrolase activity" EXACT [EC:3.6.1.5] +synonym: "ATP-diphosphatase activity" EXACT [EC:3.6.1.5] +xref: MetaCyc:APYRASE-RXN +is_a: GO:0017110 ! nucleoside-diphosphatase activity + +[Term] +id: GO:0043263 +name: cellulosome +namespace: cellular_component +alt_id: GO:1990296 +def: "An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose." [GOC:jl, PMID:11601609, PMID:15197390, PMID:20373916] +synonym: "scaffoldin complex" NARROW [] +xref: Wikipedia:Cellulosome +is_a: GO:0043264 ! extracellular non-membrane-bounded organelle +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0043264 +name: extracellular non-membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] +synonym: "extracellular non-membrane-enclosed organelle" EXACT [] +is_a: GO:0043228 ! non-membrane-bounded organelle +is_a: GO:0043230 ! extracellular organelle + +[Term] +id: GO:0043265 +name: ectoplasm +namespace: cellular_component +def: "Granule free cytoplasm, lying immediately below the plasma membrane." [GOC:curators, PMID:12211103] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0043266 +name: regulation of potassium ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "regulation of K+ conductance" NARROW [] +synonym: "regulation of K+ transport" EXACT [] +synonym: "regulation of potassium conductance" NARROW [] +synonym: "regulation of potassium ion conductance" NARROW [] +synonym: "regulation of potassium transport" EXACT [] +is_a: GO:0010959 ! regulation of metal ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006813 ! potassium ion transport +relationship: regulates GO:0006813 ! potassium ion transport + +[Term] +id: GO:0043267 +name: negative regulation of potassium ion transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "down regulation of potassium ion transport" EXACT [] +synonym: "down-regulation of potassium ion transport" EXACT [] +synonym: "downregulation of potassium ion transport" EXACT [] +synonym: "inhibition of potassium ion transport" NARROW [] +synonym: "negative regulation of K+ transport" EXACT [] +synonym: "negative regulation of potassium ion conductance" NARROW [] +synonym: "negative regulation of potassium transport" EXACT [] +synonym: "regulation of K+ conductance" NARROW [] +synonym: "regulation of potassium conductance" NARROW [] +synonym: "transmembrane conductance regulator activity" RELATED [] +is_a: GO:0043266 ! regulation of potassium ion transport +is_a: GO:0043271 ! negative regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006813 ! potassium ion transport +relationship: negatively_regulates GO:0006813 ! potassium ion transport + +[Term] +id: GO:0043268 +name: positive regulation of potassium ion transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "activation of potassium ion transport" NARROW [] +synonym: "positive regulation of K+ conductance" NARROW [] +synonym: "positive regulation of K+ transport" EXACT [] +synonym: "positive regulation of potassium conductance" NARROW [] +synonym: "positive regulation of potassium ion conductance" NARROW [] +synonym: "positive regulation of potassium transport" EXACT [] +synonym: "stimulation of potassium ion transport" NARROW [] +synonym: "up regulation of potassium ion transport" EXACT [] +synonym: "up-regulation of potassium ion transport" EXACT [] +synonym: "upregulation of potassium ion transport" EXACT [] +is_a: GO:0043266 ! regulation of potassium ion transport +is_a: GO:0043270 ! positive regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006813 ! potassium ion transport +relationship: positively_regulates GO:0006813 ! potassium ion transport + +[Term] +id: GO:0043269 +name: regulation of ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006811 ! ion transport +relationship: regulates GO:0006811 ! ion transport + +[Term] +id: GO:0043270 +name: positive regulation of ion transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "activation of ion transport" NARROW [] +synonym: "stimulation of ion transport" NARROW [] +synonym: "up regulation of ion transport" EXACT [] +synonym: "up-regulation of ion transport" EXACT [] +synonym: "upregulation of ion transport" EXACT [] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006811 ! ion transport +relationship: positively_regulates GO:0006811 ! ion transport + +[Term] +id: GO:0043271 +name: negative regulation of ion transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +synonym: "down regulation of ion transport" EXACT [] +synonym: "down-regulation of ion transport" EXACT [] +synonym: "downregulation of ion transport" EXACT [] +synonym: "inhibition of ion transport" NARROW [] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006811 ! ion transport +relationship: negatively_regulates GO:0006811 ! ion transport + +[Term] +id: GO:0043272 +name: ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance." [GOC:jl] +synonym: "ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance" RELATED [] +synonym: "ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance" RELATED [GOC:dph, GOC:tb] +synonym: "ethylene formation during jasmonic acid and ethylene-dependent systemic resistance" RELATED [] +synonym: "ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance" RELATED [] +is_a: GO:0009693 ! ethylene biosynthetic process +intersection_of: GO:0009693 ! ethylene biosynthetic process +intersection_of: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance +relationship: part_of GO:0009861 ! jasmonic acid and ethylene-dependent systemic resistance + +[Term] +id: GO:0043273 +name: CTPase activity +namespace: molecular_function +alt_id: GO:0061747 +alt_id: GO:0061748 +def: "Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction." [GOC:go_curators] +synonym: "CTPase activity, coupled" RELATED [] +synonym: "cytidine triphosphatase activity" EXACT [] +synonym: "single-stranded DNA-dependent CTPase activity" NARROW [] +is_a: GO:0017111 ! nucleoside-triphosphatase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19078 xsd:anyURI +created_by: dph +creation_date: 2015-11-11T13:05:32Z + +[Term] +id: GO:0043274 +name: phospholipase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid." [GOC:jl] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0043275 +name: obsolete glutamate carboxypeptidase II activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu." [BRENDA:3.4.17.21, GOC:jl] +comment: This term was made obsolete because it represents a gene product. +synonym: "acetylaspartylglutamate dipeptidase activity" EXACT [] +synonym: "folate hydrolase activity" RELATED [EC:3.4.17.21] +synonym: "folylpolyglutamate hydrolase activity" EXACT [EC:3.4.17.21] +synonym: "glutamate carboxypeptidase II activity" EXACT [] +synonym: "membrane glutamate carboxypeptidase" NARROW [EC:3.4.17.21] +synonym: "mGCP" RELATED [EC:3.4.17.21] +synonym: "microsomal gamma-glutamyl carboxypeptidase" NARROW [EC:3.4.17.21] +synonym: "N-acetylated alpha-linked acidic dipeptidase activity" EXACT [EC:3.4.17.21] +synonym: "N-acetylated-alpha-linked-amino dipeptidase activity" EXACT [EC:3.4.17.21] +synonym: "N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)" EXACT [EC:3.4.17.21] +synonym: "N-acetylated-gamma-linked-acidic dipeptidase activity" EXACT [EC:3.4.17.21] +synonym: "NAALA dipeptidase activity" EXACT [EC:3.4.17.21] +synonym: "NAALADase activity" EXACT [EC:3.4.17.21] +synonym: "prostate-specific membrane antigen" RELATED [EC:3.4.17.21] +synonym: "prostrate-specific membrane antigen" RELATED [EC:3.4.17.21] +synonym: "PSM antigen" RELATED [EC:3.4.17.21] +synonym: "PSMA" RELATED [EC:3.4.17.21] +synonym: "pteroylpoly-gamma-glutamate carboxypeptidase activity" EXACT [EC:3.4.17.21] +synonym: "pteroylpoly-gamma-glutamate hydrolase activity" EXACT [EC:3.4.17.21] +synonym: "pteroylpolygammaglutamyl hydrolase activity" EXACT [EC:3.4.17.21] +synonym: "pteroylpolyglutamate hydrolase activity" EXACT [EC:3.4.17.21] +synonym: "pteroylpolyglutamic acid hydrolase activity" EXACT [EC:3.4.17.21] +synonym: "rat NAAG peptidase" NARROW [EC:3.4.17.21] +xref: EC:3.4.17.21 +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0043276 +name: anoikis +namespace: biological_process +def: "Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix." [GOC:jl, http://www.copewithcytokines.de/] +synonym: "detachment induced cell death" EXACT [] +synonym: "suspension induced apoptosis" EXACT [] +xref: Wikipedia:Anoikis +is_a: GO:0006915 ! apoptotic process + +[Term] +id: GO:0043277 +name: apoptotic cell clearance +namespace: biological_process +def: "The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte." [GOC:rk, PMID:14685684] +comment: Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells. +synonym: "apoptotic cell removal" EXACT [] +synonym: "efferocytosis" EXACT [PMID:17548650] +synonym: "programmed cell clearance" EXACT [] +is_a: GO:0006909 ! phagocytosis + +[Term] +id: GO:0043278 +name: response to morphine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure." [GOC:ef, GOC:jl] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014072 ! response to isoquinoline alkaloid +is_a: GO:0072347 ! response to anesthetic + +[Term] +id: GO:0043279 +name: response to alkaloid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] +is_a: GO:0010243 ! response to organonitrogen compound + +[Term] +id: GO:0043280 +name: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +def: "Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process." [GOC:jl, GOC:mtg_apoptosis] +synonym: "activation of caspase activity" NARROW [] +synonym: "positive regulation of caspase activity" BROAD [] +synonym: "stimulation of caspase activity" NARROW [] +synonym: "up regulation of caspase activity" EXACT [] +synonym: "up-regulation of caspase activity" EXACT [] +synonym: "upregulation of caspase activity" EXACT [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0043281 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:2001056 ! positive regulation of cysteine-type endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process +relationship: positively_regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0043281 +name: regulation of cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +alt_id: GO:0043026 +def: "Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis." [GOC:jl, GOC:mtg_apoptosis] +synonym: "regulation of caspase activation" NARROW [] +synonym: "regulation of caspase activity" BROAD [] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:2000116 ! regulation of cysteine-type endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process +relationship: regulates GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process + +[Term] +id: GO:0043282 +name: pharyngeal muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx." [GOC:go_curators] +is_a: GO:0007517 ! muscle organ development +relationship: part_of GO:0060465 ! pharynx development + +[Term] +id: GO:0043286 +name: regulation of poly(3-hydroxyalkanoate) biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria." [GOC:jl] +synonym: "regulation of PHA" EXACT [] +synonym: "regulation of poly(3-hydroxyalkanoate) anabolism" EXACT [] +synonym: "regulation of poly(3-hydroxyalkanoate) biosynthesis" EXACT [] +synonym: "regulation of poly(3-hydroxyalkanoate) formation" EXACT [] +synonym: "regulation of poly(3-hydroxyalkanoate) synthesis" EXACT [] +is_a: GO:0009889 ! regulation of biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042621 ! poly(3-hydroxyalkanoate) biosynthetic process +relationship: regulates GO:0042621 ! poly(3-hydroxyalkanoate) biosynthetic process + +[Term] +id: GO:0043287 +name: poly(3-hydroxyalkanoate) binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria." [GOC:jl] +synonym: "PHA binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0043288 +name: apocarotenoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid." [GOC:jl] +synonym: "apo carotenoid metabolic process" EXACT [] +synonym: "apocarotenoid metabolism" EXACT [] +is_a: GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0043289 +name: apocarotenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid." [GOC:jl, PMID:27485225] +synonym: "apo carotenoid biosynthetic process" EXACT [] +synonym: "apocarotenoid anabolism" EXACT [] +synonym: "apocarotenoid biosynthesis" EXACT [] +synonym: "apocarotenoid formation" EXACT [] +synonym: "apocarotenoid synthesis" EXACT [] +is_a: GO:0008299 ! isoprenoid biosynthetic process +is_a: GO:0043288 ! apocarotenoid metabolic process + +[Term] +id: GO:0043290 +name: apocarotenoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid." [GOC:jl, http://www.msu.edu/~schwart1/apocarotenoids.htm] +synonym: "apo carotenoid catabolic process" EXACT [] +synonym: "apocarotenoid breakdown" EXACT [] +synonym: "apocarotenoid catabolism" EXACT [] +synonym: "apocarotenoid degradation" EXACT [] +is_a: GO:0008300 ! isoprenoid catabolic process +is_a: GO:0043288 ! apocarotenoid metabolic process + +[Term] +id: GO:0043291 +name: RAVE complex +namespace: cellular_component +def: "A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme." [PMID:11283612, PMID:11844802] +synonym: "regulator of the (H+)-ATPase of the vacuolar and endosomal membranes" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0043292 +name: contractile fiber +namespace: cellular_component +def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] +synonym: "contractile fibre" EXACT [] +synonym: "muscle fiber" BROAD [] +synonym: "muscle fibre" BROAD [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +is_a: GO:0099512 ! supramolecular fiber +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0043293 +name: apoptosome +namespace: cellular_component +def: "A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms." [GOC:mtg_apoptosis, PMID:10428850, PMID:11406413, PMID:12176339, PMID:15189137] +xref: Wikipedia:Apoptosome +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0043294 +name: mitochondrial glutamate synthase complex (NADH) +namespace: cellular_component +def: "A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity." [GOC:jl, PMID:7047525] +is_a: GO:0031027 ! glutamate synthase complex (NADH) +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0031027 ! glutamate synthase complex (NADH) +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005759 ! mitochondrial matrix + +[Term] +id: GO:0043295 +name: glutathione binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine." [GOC:bf, ISBN:0198506732] +is_a: GO:0043168 ! anion binding +is_a: GO:0048037 ! cofactor binding +is_a: GO:0072341 ! modified amino acid binding +is_a: GO:1900750 ! oligopeptide binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043296 +name: apical junction complex +namespace: cellular_component +def: "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." [GOC:go_curators, GOC:kmv, PMID:12525486, PMID:15196556] +synonym: "apical cell junction complex" EXACT [GOC:mah] +synonym: "apical junction" EXACT [] +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0043297 +name: apical junction assembly +namespace: biological_process +def: "The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents." [GOC:go_curators, PMID:10854689, PMID:14729475, PMID:15196556] +synonym: "apical junction complex assembly" EXACT [GOC:mah] +is_a: GO:0007043 ! cell-cell junction assembly + +[Term] +id: GO:0043299 +name: leukocyte degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] +synonym: "immune cell degranulation" EXACT [] +synonym: "immune cell granule exocytosis" EXACT [] +synonym: "leucocyte degranulation" EXACT [] +synonym: "leukocyte granule exocytosis" EXACT [] +is_a: GO:0002252 ! immune effector process +is_a: GO:0045055 ! regulated exocytosis +is_a: GO:0051649 ! establishment of localization in cell + +[Term] +id: GO:0043300 +name: regulation of leukocyte degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of leukocyte degranulation." [GOC:add, ISBN:0781735149] +synonym: "regulation of immune cell degranulation" EXACT [] +synonym: "regulation of immune cell granule exocytosis" EXACT [] +synonym: "regulation of leucocyte degranulation" EXACT [] +synonym: "regulation of leukocyte granule exocytosis" EXACT [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:1903305 ! regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043299 ! leukocyte degranulation +relationship: regulates GO:0043299 ! leukocyte degranulation + +[Term] +id: GO:0043301 +name: negative regulation of leukocyte degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of leukocyte degranulation." [GOC:add, ISBN:0781735149] +synonym: "down regulation of leukocyte degranulation" EXACT [] +synonym: "down-regulation of leukocyte degranulation" EXACT [] +synonym: "downregulation of leukocyte degranulation" EXACT [] +synonym: "inhibition of leukocyte degranulation" NARROW [] +synonym: "negative regulation of immune cell degranulation" EXACT [] +synonym: "negative regulation of leucocyte degranulation" EXACT [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:1903306 ! negative regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043299 ! leukocyte degranulation +relationship: negatively_regulates GO:0043299 ! leukocyte degranulation + +[Term] +id: GO:0043302 +name: positive regulation of leukocyte degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte degranulation." [GOC:add, ISBN:0781735149] +synonym: "activation of leukocyte degranulation" NARROW [] +synonym: "positive regulation of immune cell degranulation" EXACT [] +synonym: "positive regulation of leucocyte degranulation" EXACT [] +synonym: "stimulation of leukocyte degranulation" NARROW [] +synonym: "up regulation of leukocyte degranulation" EXACT [] +synonym: "up-regulation of leukocyte degranulation" EXACT [] +synonym: "upregulation of leukocyte degranulation" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:1903307 ! positive regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043299 ! leukocyte degranulation +relationship: positively_regulates GO:0043299 ! leukocyte degranulation + +[Term] +id: GO:0043303 +name: mast cell degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell." [ISBN:0781735149] +synonym: "mast cell granule exocytosis" EXACT [] +is_a: GO:0002279 ! mast cell activation involved in immune response +is_a: GO:0032418 ! lysosome localization +is_a: GO:0043299 ! leukocyte degranulation +is_a: GO:0046907 ! intracellular transport +is_a: GO:0051656 ! establishment of organelle localization +relationship: occurs_in GO:0042629 ! mast cell granule +relationship: part_of GO:0002448 ! mast cell mediated immunity + +[Term] +id: GO:0043304 +name: regulation of mast cell degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mast cell degranulation." [ISBN:0781735149] +synonym: "regulation of mast cell granule exocytosis" EXACT [] +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0033006 ! regulation of mast cell activation involved in immune response +is_a: GO:0043300 ! regulation of leukocyte degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043303 ! mast cell degranulation +relationship: regulates GO:0043303 ! mast cell degranulation + +[Term] +id: GO:0043305 +name: negative regulation of mast cell degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of mast cell degranulation." [ISBN:0781735149] +synonym: "down regulation of mast cell degranulation" EXACT [] +synonym: "down-regulation of mast cell degranulation" EXACT [] +synonym: "downregulation of mast cell degranulation" EXACT [] +synonym: "inhibition of mast cell degranulation" NARROW [] +synonym: "negative regulation of mast cell granule exocytosis" EXACT [] +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0033007 ! negative regulation of mast cell activation involved in immune response +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0043304 ! regulation of mast cell degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043303 ! mast cell degranulation +relationship: negatively_regulates GO:0043303 ! mast cell degranulation + +[Term] +id: GO:0043306 +name: positive regulation of mast cell degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mast cell degranulation." [ISBN:0781735149] +synonym: "activation of mast cell degranulation" NARROW [] +synonym: "positive regulation of mast cell granule exocytosis" EXACT [] +synonym: "stimulation of mast cell degranulation" NARROW [] +synonym: "up regulation of mast cell degranulation" EXACT [] +synonym: "up-regulation of mast cell degranulation" EXACT [] +synonym: "upregulation of mast cell degranulation" EXACT [] +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0033008 ! positive regulation of mast cell activation involved in immune response +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0043304 ! regulation of mast cell degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043303 ! mast cell degranulation +relationship: positively_regulates GO:0043303 ! mast cell degranulation + +[Term] +id: GO:0043307 +name: eosinophil activation +namespace: biological_process +def: "The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:add, ISBN:0781735149] +is_a: GO:0036230 ! granulocyte activation + +[Term] +id: GO:0043308 +name: eosinophil degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil." [ISBN:0781735149] +synonym: "eosinophil granule exocytosis" EXACT [] +is_a: GO:0002278 ! eosinophil activation involved in immune response +is_a: GO:0043299 ! leukocyte degranulation +relationship: part_of GO:0002447 ! eosinophil mediated immunity + +[Term] +id: GO:0043309 +name: regulation of eosinophil degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of eosinophil degranulation." [ISBN:0781735149] +synonym: "regulation of eosinophil granule exocytosis" EXACT [] +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:0050776 ! regulation of immune response +is_a: GO:1902566 ! regulation of eosinophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043308 ! eosinophil degranulation +relationship: regulates GO:0043308 ! eosinophil degranulation + +[Term] +id: GO:0043310 +name: negative regulation of eosinophil degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of eosinophil degranulation." [ISBN:0781735149] +synonym: "down regulation of eosinophil degranulation" EXACT [] +synonym: "down-regulation of eosinophil degranulation" EXACT [] +synonym: "downregulation of eosinophil degranulation" EXACT [] +synonym: "inhibition of eosinophil degranulation" NARROW [] +synonym: "negative regulation of eosinophil granule exocytosis" EXACT [] +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0043309 ! regulation of eosinophil degranulation +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:1902567 ! negative regulation of eosinophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043308 ! eosinophil degranulation +relationship: negatively_regulates GO:0043308 ! eosinophil degranulation + +[Term] +id: GO:0043311 +name: positive regulation of eosinophil degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil degranulation." [ISBN:0781735149] +synonym: "activation of eosinophil degranulation" NARROW [] +synonym: "positive regulation of eosinophil granule exocytosis" EXACT [] +synonym: "stimulation of eosinophil degranulation" NARROW [] +synonym: "up regulation of eosinophil degranulation" EXACT [] +synonym: "up-regulation of eosinophil degranulation" EXACT [] +synonym: "upregulation of eosinophil degranulation" EXACT [] +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0043309 ! regulation of eosinophil degranulation +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:1902568 ! positive regulation of eosinophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043308 ! eosinophil degranulation +relationship: positively_regulates GO:0043308 ! eosinophil degranulation + +[Term] +id: GO:0043312 +name: neutrophil degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil." [ISBN:0781735149] +synonym: "heterophil degranulation" RELATED [] +synonym: "neutrophil granule exocytosis" EXACT [] +is_a: GO:0002283 ! neutrophil activation involved in immune response +is_a: GO:0043299 ! leukocyte degranulation +relationship: part_of GO:0002446 ! neutrophil mediated immunity + +[Term] +id: GO:0043313 +name: regulation of neutrophil degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of neutrophil degranulation." [ISBN:0781735149] +synonym: "regulation of neutrophil granule exocytosis" EXACT [] +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:0050776 ! regulation of immune response +is_a: GO:1902563 ! regulation of neutrophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043312 ! neutrophil degranulation +relationship: regulates GO:0043312 ! neutrophil degranulation + +[Term] +id: GO:0043314 +name: negative regulation of neutrophil degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of neutrophil degranulation." [ISBN:0781735149] +synonym: "down regulation of neutrophil degranulation" EXACT [] +synonym: "down-regulation of neutrophil degranulation" EXACT [] +synonym: "downregulation of neutrophil degranulation" EXACT [] +synonym: "inhibition of neutrophil degranulation" NARROW [] +synonym: "negative regulation of neutrophil granule exocytosis" EXACT [] +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0043313 ! regulation of neutrophil degranulation +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:1902564 ! negative regulation of neutrophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043312 ! neutrophil degranulation +relationship: negatively_regulates GO:0043312 ! neutrophil degranulation + +[Term] +id: GO:0043315 +name: positive regulation of neutrophil degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil degranulation." [ISBN:0781735149] +synonym: "activation of neutrophil degranulation" NARROW [] +synonym: "positive regulation of neutrophil granule exocytosis" EXACT [] +synonym: "stimulation of neutrophil degranulation" NARROW [] +synonym: "up regulation of neutrophil degranulation" EXACT [] +synonym: "up-regulation of neutrophil degranulation" EXACT [] +synonym: "upregulation of neutrophil degranulation" EXACT [] +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0043313 ! regulation of neutrophil degranulation +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:1902565 ! positive regulation of neutrophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043312 ! neutrophil degranulation +relationship: positively_regulates GO:0043312 ! neutrophil degranulation + +[Term] +id: GO:0043316 +name: cytotoxic T cell degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell." [ISBN:0781735149] +synonym: "cytotoxic T cell granule exocytosis" EXACT [] +synonym: "cytotoxic T lymphocyte degranulation" EXACT [] +synonym: "cytotoxic T lymphocyte granule exocytosis" EXACT [] +synonym: "cytotoxic T-cell degranulation" EXACT [] +synonym: "cytotoxic T-cell granule exocytosis" EXACT [] +synonym: "cytotoxic T-lymphocyte degranulation" EXACT [] +synonym: "cytotoxic T-lymphocyte granule exocytosis" EXACT [] +is_a: GO:0002286 ! T cell activation involved in immune response +is_a: GO:0043299 ! leukocyte degranulation +relationship: part_of GO:0001913 ! T cell mediated cytotoxicity + +[Term] +id: GO:0043317 +name: regulation of cytotoxic T cell degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation." [ISBN:0781735149] +synonym: "regulation of cytotoxic T cell granule exocytosis" EXACT [] +synonym: "regulation of cytotoxic T lymphocyte degranulation" EXACT [] +synonym: "regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] +synonym: "regulation of cytotoxic T-cell degranulation" EXACT [] +synonym: "regulation of cytotoxic T-cell granule exocytosis" EXACT [] +synonym: "regulation of cytotoxic T-lymphocyte degranulation" EXACT [] +synonym: "regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] +is_a: GO:0001914 ! regulation of T cell mediated cytotoxicity +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043316 ! cytotoxic T cell degranulation +relationship: regulates GO:0043316 ! cytotoxic T cell degranulation + +[Term] +id: GO:0043318 +name: negative regulation of cytotoxic T cell degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation." [ISBN:0781735149] +synonym: "down regulation of cytotoxic T cell degranulation" EXACT [] +synonym: "down-regulation of cytotoxic T cell degranulation" EXACT [] +synonym: "downregulation of cytotoxic T cell degranulation" EXACT [] +synonym: "inhibition of cytotoxic T cell degranulation" NARROW [] +synonym: "negative regulation of cytotoxic T cell granule exocytosis" EXACT [] +synonym: "negative regulation of cytotoxic T lymphocyte degranulation" EXACT [] +synonym: "negative regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] +synonym: "negative regulation of cytotoxic T-cell degranulation" EXACT [] +synonym: "negative regulation of cytotoxic T-cell granule exocytosis" EXACT [] +synonym: "negative regulation of cytotoxic T-lymphocyte degranulation" EXACT [] +synonym: "negative regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] +is_a: GO:0001915 ! negative regulation of T cell mediated cytotoxicity +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0043317 ! regulation of cytotoxic T cell degranulation +is_a: GO:0050868 ! negative regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043316 ! cytotoxic T cell degranulation +relationship: negatively_regulates GO:0043316 ! cytotoxic T cell degranulation + +[Term] +id: GO:0043319 +name: positive regulation of cytotoxic T cell degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation." [ISBN:0781735149] +synonym: "activation of cytotoxic T cell degranulation" NARROW [] +synonym: "positive regulation of cytotoxic T cell granule exocytosis" EXACT [] +synonym: "positive regulation of cytotoxic T lymphocyte degranulation" EXACT [] +synonym: "positive regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] +synonym: "positive regulation of cytotoxic T-cell degranulation" EXACT [] +synonym: "positive regulation of cytotoxic T-cell granule exocytosis" EXACT [] +synonym: "positive regulation of cytotoxic T-lymphocyte degranulation" EXACT [] +synonym: "positive regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] +synonym: "stimulation of cytotoxic T cell degranulation" NARROW [] +synonym: "up regulation of cytotoxic T cell degranulation" EXACT [] +synonym: "up-regulation of cytotoxic T cell degranulation" EXACT [] +synonym: "upregulation of cytotoxic T cell degranulation" EXACT [] +is_a: GO:0001916 ! positive regulation of T cell mediated cytotoxicity +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0043317 ! regulation of cytotoxic T cell degranulation +is_a: GO:0050870 ! positive regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043316 ! cytotoxic T cell degranulation +relationship: positively_regulates GO:0043316 ! cytotoxic T cell degranulation + +[Term] +id: GO:0043320 +name: natural killer cell degranulation +namespace: biological_process +def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell." [ISBN:0781735149] +synonym: "natural killer cell granule exocytosis" EXACT [] +synonym: "NK cell degranulation" EXACT [] +synonym: "NK cell granule exocytosis" EXACT [] +is_a: GO:0002323 ! natural killer cell activation involved in immune response +is_a: GO:0043299 ! leukocyte degranulation +relationship: part_of GO:0042267 ! natural killer cell mediated cytotoxicity + +[Term] +id: GO:0043321 +name: regulation of natural killer cell degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of natural killer cell degranulation." [ISBN:0781735149] +synonym: "regulation of natural killer cell granule exocytosis" EXACT [] +synonym: "regulation of NK cell degranulation" EXACT [] +synonym: "regulation of NK cell granule exocytosis" EXACT [] +is_a: GO:0032814 ! regulation of natural killer cell activation +is_a: GO:0042269 ! regulation of natural killer cell mediated cytotoxicity +is_a: GO:0043300 ! regulation of leukocyte degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043320 ! natural killer cell degranulation +relationship: regulates GO:0043320 ! natural killer cell degranulation + +[Term] +id: GO:0043322 +name: negative regulation of natural killer cell degranulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of natural killer cell degranulation." [ISBN:0781735149] +synonym: "down regulation of natural killer cell degranulation" EXACT [] +synonym: "down-regulation of natural killer cell degranulation" EXACT [] +synonym: "downregulation of natural killer cell degranulation" EXACT [] +synonym: "inhibition of natural killer cell degranulation" NARROW [] +synonym: "negative regulation of natural killer cell granule exocytosis" EXACT [] +synonym: "negative regulation of NK cell degranulation" EXACT [] +synonym: "negative regulation of NK cell granule exocytosis" EXACT [] +is_a: GO:0032815 ! negative regulation of natural killer cell activation +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0043321 ! regulation of natural killer cell degranulation +is_a: GO:0045953 ! negative regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043320 ! natural killer cell degranulation +relationship: negatively_regulates GO:0043320 ! natural killer cell degranulation + +[Term] +id: GO:0043323 +name: positive regulation of natural killer cell degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation." [ISBN:0781735149] +synonym: "activation of natural killer cell degranulation" NARROW [] +synonym: "positive regulation of natural killer cell granule exocytosis" EXACT [] +synonym: "positive regulation of NK cell degranulation" EXACT [] +synonym: "positive regulation of NK cell granule exocytosis" EXACT [] +synonym: "stimulation of natural killer cell degranulation" NARROW [] +synonym: "up regulation of natural killer cell degranulation" EXACT [] +synonym: "up-regulation of natural killer cell degranulation" EXACT [] +synonym: "upregulation of natural killer cell degranulation" EXACT [] +is_a: GO:0032816 ! positive regulation of natural killer cell activation +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0043321 ! regulation of natural killer cell degranulation +is_a: GO:0045954 ! positive regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043320 ! natural killer cell degranulation +relationship: positively_regulates GO:0043320 ! natural killer cell degranulation + +[Term] +id: GO:0043324 +name: pigment metabolic process involved in developmental pigmentation +namespace: biological_process +def: "The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism." [GOC:jl, ISBN:0198506732] +synonym: "pigment metabolic process during developmental pigmentation" RELATED [GOC:dph, GOC:tb] +synonym: "pigment metabolism during developmental pigmentation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043474 ! pigment metabolic process involved in pigmentation +intersection_of: GO:0042440 ! pigment metabolic process +intersection_of: part_of GO:0048066 ! developmental pigmentation +relationship: part_of GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0043325 +name: phosphatidylinositol-3,4-bisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions." [GOC:bf, GOC:go_curators] +is_a: GO:1902936 ! phosphatidylinositol bisphosphate binding + +[Term] +id: GO:0043326 +name: chemotaxis to folate +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to the presence of folate." [GOC:go_curators] +is_a: GO:0006935 ! chemotaxis +is_a: GO:0051593 ! response to folic acid + +[Term] +id: GO:0043327 +name: chemotaxis to cAMP +namespace: biological_process +def: "The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP." [GOC:go_curators] +synonym: "chemotaxis to 3',5' cAMP" EXACT [] +synonym: "chemotaxis to 3',5'-cAMP" EXACT [] +synonym: "chemotaxis to adenosine 3',5'-cyclophosphate" EXACT [] +synonym: "chemotaxis to cyclic AMP" EXACT [] +is_a: GO:0006935 ! chemotaxis + +[Term] +id: GO:0043328 +name: protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway +namespace: biological_process +def: "The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway." [GOC:jl, PMID:11511343] +synonym: "protein targeting to vacuole during ubiquitin-dependent protein breakdown via the MVB pathway" EXACT [] +synonym: "protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway" RELATED [GOC:dph, GOC:tb] +synonym: "protein targeting to vacuole during ubiquitin-dependent protein degradation via the MVB pathway" EXACT [] +synonym: "protein vacuolar targeting during ubiquitin-dependent protein catabolic process via the MVB pathway" EXACT [] +synonym: "protein vacuolar targeting during ubiquitin-dependent protein catabolism via the MVB pathway" EXACT [] +synonym: "protein-vacuolar targeting during ubiquitin-dependent protein breakdown via the MVB pathway" EXACT [] +synonym: "protein-vacuolar targeting during ubiquitin-dependent protein degradation via the MVB pathway" EXACT [] +synonym: "protein-vacuole targeting during ubiquitin-dependent protein catabolic process via the MVB pathway" EXACT [] +synonym: "protein-vacuole targeting during ubiquitin-dependent protein catabolism via the MVB pathway" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0032511 ! late endosome to vacuole transport via multivesicular body sorting pathway +is_a: GO:0072666 ! establishment of protein localization to vacuole +intersection_of: GO:0072666 ! establishment of protein localization to vacuole +intersection_of: part_of GO:0043162 ! ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway +relationship: part_of GO:0043162 ! ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway + +[Term] +id: GO:0043329 +name: obsolete protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway +namespace: biological_process +def: "OBSOLETE. The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway." [GOC:jl] +comment: The reason for obsoleting is that the term is not cleary defined, ie the membrane to which proteins are being targeted is not specified. +synonym: "protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway" EXACT [] +synonym: "protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway" EXACT [] +synonym: "protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway" EXACT [] +synonym: "protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway" RELATED [GOC:dph, GOC:tb] +synonym: "protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway" EXACT [] +synonym: "protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway" EXACT [] +synonym: "protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway" EXACT [] +synonym: "protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway" EXACT [] +synonym: "protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0043330 +name: response to exogenous dsRNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus." [GOC:go_curators] +comment: Note that the presence of exogenous double-stranded RNA is usually indicative of a viral infection. Consider also annotating to 'response to virus ; GO:0009615'. +synonym: "response to exogenous double-stranded RNA" EXACT [] +synonym: "response to viral dsRNA" NARROW [] +is_a: GO:0043331 ! response to dsRNA + +[Term] +id: GO:0043331 +name: response to dsRNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus." [GOC:jl] +synonym: "response to double-stranded RNA" EXACT [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901698 ! response to nitrogen compound + +[Term] +id: GO:0043332 +name: mating projection tip +namespace: cellular_component +def: "The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth." [GOC:mcc] +synonym: "conjugation tube tip" NARROW [] +synonym: "shmoo tip" NARROW [] +is_a: GO:0030427 ! site of polarized growth +is_a: GO:0051286 ! cell tip +intersection_of: GO:0030427 ! site of polarized growth +intersection_of: part_of GO:0005937 ! mating projection +relationship: part_of GO:0005937 ! mating projection + +[Term] +id: GO:0043333 +name: 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity +namespace: molecular_function +alt_id: GO:0102005 +def: "Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9045837] +comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. +synonym: "2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity" EXACT [] +xref: EC:2.1.1.201 +xref: MetaCyc:2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN +is_a: GO:0008425 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + +[Term] +id: GO:0043334 +name: 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9083048] +comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. +synonym: "2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] +is_a: GO:0008425 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + +[Term] +id: GO:0043335 +name: protein unfolding +namespace: biological_process +def: "The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state." [GOC:mlg] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0043336 +name: site-specific telomere resolvase activity +namespace: molecular_function +def: "Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases." [GOC:jl, PMID:11804598] +comment: Note that while this enzyme uses a similar reaction chemistry to topoisomerases and site-specific recombinases, it performs a unique reaction. Topoisomerases promote breakage and reunion of either one or two DNA strands to alter the topological state of a DNA molecule. Site-specific recombinases perform a more complex reaction in which four strands are broken and subsequently joined to a different DNA duplex, resulting in the production of a recombinant product. The telomere resolvases on the other hand, must break two phosphodiester bonds in a single DNA duplex (one on each strand) and join each end with the opposite DNA strand to form covalently closed hairpin telomeres. +synonym: "ResT" NARROW [] +synonym: "TelN" NARROW [] +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0000723 ! telomere maintenance + +[Term] +id: GO:0043337 +name: CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol." [GOC:jl] +synonym: "cardiolipin synthase" BROAD [] +synonym: "cardiolipin synthetase" BROAD [] +xref: MetaCyc:RXN-8141 +xref: Reactome:R-HSA-1483063 "PG and CDP-DAG are converted to CL by CRLS1" +is_a: GO:0030572 ! phosphatidyltransferase activity + +[Term] +id: GO:0043338 +name: CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol." [GOC:jl, PMID:10960477, RHEA:25690] +synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase" BROAD [] +xref: EC:2.7.7.67 +xref: RHEA:25690 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0043353 +name: enucleate erythrocyte differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." [GOC:go_curators] +synonym: "enucleate RBC differentiation" EXACT [CL:0000232] +synonym: "enucleate red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0043354 +name: enucleate erythrocyte maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." [GOC:go_curators] +synonym: "enucleate RBC maturation" EXACT [CL:0000232] +synonym: "enucleate red blood cell maturation" EXACT [CL:0000232] +is_a: GO:0043249 ! erythrocyte maturation +relationship: part_of GO:0048822 ! enucleate erythrocyte development + +[Term] +id: GO:0043362 +name: nucleate erythrocyte maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl] +synonym: "nucleate RBC maturation" EXACT [CL:0000232] +synonym: "nucleate red blood cell maturation" EXACT [CL:0000232] +is_a: GO:0043249 ! erythrocyte maturation +relationship: part_of GO:0048823 ! nucleate erythrocyte development + +[Term] +id: GO:0043363 +name: nucleate erythrocyte differentiation +namespace: biological_process +def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl] +synonym: "nucleate RBC differentiation" EXACT [CL:0000232] +synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0043364 +name: glycyl-radical enzyme activating activity +namespace: molecular_function +def: "Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM)." [GOC:jl, PMID:24486374] +subset: goslim_pir +synonym: "catalysis of free radical formation" BROAD [] +xref: EC:1.97.1 +is_a: GO:0016491 ! oxidoreductase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14190 xsd:anyURI + +[Term] +id: GO:0043365 +name: [formate-C-acetyltransferase]-activating enzyme activity +namespace: molecular_function +alt_id: GO:0008862 +def: "Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical." [EC:1.97.1.4, GOC:jl, PMID:18307109] +synonym: "[pyruvate formate-lyase]-activating enzyme activity" EXACT [EC:1.97.1.4] +synonym: "formate acetyltransferase activating enzyme activity" EXACT [EC:1.97.1.4] +synonym: "formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity" EXACT [EC:1.97.1.4] +synonym: "formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)" EXACT [EC:1.97.1.4] +synonym: "formate-C-acetyltransferase-activating enzyme" RELATED [EC:1.97.1.4] +synonym: "PFL activase activity" EXACT [EC:1.97.1.4] +synonym: "PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity" EXACT [EC:1.97.1.4] +synonym: "pyruvate formate-lyase-activating enzyme" RELATED [EC:1.97.1.4] +xref: EC:1.97.1.4 +xref: MetaCyc:TDCEACT-RXN +is_a: GO:0043364 ! glycyl-radical enzyme activating activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14190 xsd:anyURI + +[Term] +id: GO:0043366 +name: beta selection +namespace: biological_process +def: "The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell." [ISBN:0781735149, PMID:12220932] +is_a: GO:0045058 ! T cell selection +relationship: part_of GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0043367 +name: CD4-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell." [CL:0000624, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD4-positive, alpha beta T cell development" RELATED [GOC:add] +synonym: "CD4-positive, alpha beta T cell differentiation" EXACT [GOC:bf] +synonym: "CD4-positive, alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "CD4-positive, alpha-beta T-cell differentiation" EXACT [] +synonym: "CD4-positive, alpha-beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0035710 ! CD4-positive, alpha-beta T cell activation +is_a: GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0043368 +name: positive T cell selection +namespace: biological_process +def: "The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death." [ISBN:0781735149, PMID:12414722] +synonym: "positive T lymphocyte selection" EXACT [] +synonym: "positive T-cell selection" EXACT [] +synonym: "positive T-lymphocyte selection" EXACT [] +is_a: GO:0045058 ! T cell selection + +[Term] +id: GO:0043369 +name: CD4-positive or CD8-positive, alpha-beta T cell lineage commitment +namespace: biological_process +def: "The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells." [ISBN:0781735149] +synonym: "CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment" EXACT [] +synonym: "CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment" EXACT [] +synonym: "CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment" EXACT [] +synonym: "CD4-positive/CD8-positive, alpha-beta T cell lineage commitment" EXACT [] +is_a: GO:0002360 ! T cell lineage commitment +relationship: part_of GO:0043368 ! positive T cell selection + +[Term] +id: GO:0043370 +name: regulation of CD4-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation." [GOC:add, GOC:pr, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of CD4-positive T lymphocyte differentiation" EXACT [] +synonym: "regulation of CD4-positive T-cell differentiation" EXACT [] +synonym: "regulation of CD4-positive T-lymphocyte differentiation" EXACT [] +synonym: "regulation of CD4-positive, alpha beta T cell development" RELATED [GOC:add] +synonym: "regulation of CD4-positive, alpha beta T cell differentiation" EXACT [GOC:bf] +synonym: "regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0046637 ! regulation of alpha-beta T cell differentiation +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +relationship: regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043371 +name: negative regulation of CD4-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation." [GOC:add, GOC:pr, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +synonym: "down-regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +synonym: "downregulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +synonym: "inhibition of CD4-positive, alpha beta T cell differentiation" NARROW [] +synonym: "negative regulation of CD4-positive T-cell differentiation" EXACT [] +synonym: "negative regulation of CD4-positive T-lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD4-positive, alpha beta T cell development" RELATED [GOC:add] +synonym: "negative regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0043370 ! regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0046639 ! negative regulation of alpha-beta T cell differentiation +is_a: GO:2000515 ! negative regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +relationship: negatively_regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043372 +name: positive regulation of CD4-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation." [GOC:add, GOC:pr, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of CD4-positive, alpha beta T cell differentiation" NARROW [] +synonym: "positive regulation of CD4-positive T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD4-positive T-cell differentiation" EXACT [] +synonym: "positive regulation of CD4-positive T-lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD4-positive, alpha beta T cell development" RELATED [GOC:add] +synonym: "positive regulation of CD4-positive, alpha beta T cell differentiation" EXACT [GOC:bf] +synonym: "positive regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of CD4-positive, alpha beta T cell differentiation" NARROW [] +synonym: "up regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +synonym: "up-regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +synonym: "upregulation of CD4-positive, alpha beta T cell differentiation" EXACT [] +is_a: GO:0043370 ! regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0046638 ! positive regulation of alpha-beta T cell differentiation +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation +relationship: positively_regulates GO:0043367 ! CD4-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043373 +name: CD4-positive, alpha-beta T cell lineage commitment +namespace: biological_process +def: "The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell." [ISBN:0781735149] +synonym: "CD4-positive, alpha-beta T lymphocyte lineage commitment" EXACT [] +synonym: "CD4-positive, alpha-beta T-cell lineage commitment" EXACT [] +synonym: "CD4-positive, alpha-beta T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002363 ! alpha-beta T cell lineage commitment +is_a: GO:0043369 ! CD4-positive or CD8-positive, alpha-beta T cell lineage commitment +relationship: part_of GO:0043367 ! CD4-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043374 +name: CD8-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "CD8-positive, alpha-beta T cell development" RELATED [GOC:add] +synonym: "CD8-positive, alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta T-cell differentiation" EXACT [] +synonym: "CD8-positive, alpha-beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0036037 ! CD8-positive, alpha-beta T cell activation +is_a: GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0043375 +name: CD8-positive, alpha-beta T cell lineage commitment +namespace: biological_process +def: "The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell." [ISBN:0781735149] +synonym: "CD8-positive, alpha-beta T cell fate commitment" EXACT [] +synonym: "CD8-positive, alpha-beta T lymphocyte lineage commitment" EXACT [] +synonym: "CD8-positive, alpha-beta T-cell lineage commitment" EXACT [] +synonym: "CD8-positive, alpha-beta T-lymphocyte lineage commitment" EXACT [] +is_a: GO:0002363 ! alpha-beta T cell lineage commitment +is_a: GO:0043369 ! CD4-positive or CD8-positive, alpha-beta T cell lineage commitment +relationship: part_of GO:0043374 ! CD8-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043376 +name: regulation of CD8-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of CD8-positive T lymphocyte differentiation" EXACT [] +synonym: "regulation of CD8-positive T-cell differentiation" EXACT [] +synonym: "regulation of CD8-positive T-lymphocyte differentiation" EXACT [] +synonym: "regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] +synonym: "regulation of CD8-positive, alpha-beta T cell development" RELATED [GOC:add] +is_a: GO:0046637 ! regulation of alpha-beta T cell differentiation +is_a: GO:2001185 ! regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +relationship: regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043377 +name: negative regulation of CD8-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +synonym: "down-regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +synonym: "downregulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +synonym: "inhibition of CD8-positive, alpha-beta T cell differentiation" NARROW [] +synonym: "negative regulation of CD8-positive T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD8-positive T-cell differentiation" EXACT [] +synonym: "negative regulation of CD8-positive T-lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] +synonym: "negative regulation of CD8-positive, alpha-beta T cell development" RELATED [GOC:add] +is_a: GO:0043376 ! regulation of CD8-positive, alpha-beta T cell differentiation +is_a: GO:0046639 ! negative regulation of alpha-beta T cell differentiation +is_a: GO:2001186 ! negative regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +relationship: negatively_regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043378 +name: positive regulation of CD8-positive, alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of CD8-positive, alpha-beta T cell differentiation" NARROW [] +synonym: "positive regulation of CD8-positive T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD8-positive T-cell differentiation" EXACT [] +synonym: "positive regulation of CD8-positive T-lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] +synonym: "positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] +synonym: "positive regulation of CD8-positive, alpha-beta T cell development" RELATED [GOC:add] +synonym: "stimulation of CD8-positive, alpha-beta T cell differentiation" NARROW [] +synonym: "up regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +synonym: "up-regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +synonym: "upregulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] +is_a: GO:0043376 ! regulation of CD8-positive, alpha-beta T cell differentiation +is_a: GO:0046638 ! positive regulation of alpha-beta T cell differentiation +is_a: GO:2001187 ! positive regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation +relationship: positively_regulates GO:0043374 ! CD8-positive, alpha-beta T cell differentiation + +[Term] +id: GO:0043379 +name: memory T cell differentiation +namespace: biological_process +def: "The process in which a newly activated T cell acquires specialized features of a memory T cell." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "memory T cell development" RELATED [GOC:add] +synonym: "memory T lymphocyte differentiation" EXACT [] +synonym: "memory T-cell differentiation" EXACT [] +synonym: "memory T-lymphocyte differentiation" EXACT [] +is_a: GO:0002292 ! T cell differentiation involved in immune response +is_a: GO:0090715 ! immunological memory formation process + +[Term] +id: GO:0043380 +name: regulation of memory T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of memory T cell differentiation." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of memory T cell development" RELATED [GOC:add] +synonym: "regulation of memory T lymphocyte differentiation" EXACT [] +synonym: "regulation of memory T-cell differentiation" EXACT [] +synonym: "regulation of memory T-lymphocyte differentiation" EXACT [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043379 ! memory T cell differentiation +relationship: regulates GO:0043379 ! memory T cell differentiation + +[Term] +id: GO:0043381 +name: negative regulation of memory T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of memory T cell differentiation." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of memory T cell differentiation" EXACT [] +synonym: "down-regulation of memory T cell differentiation" EXACT [] +synonym: "downregulation of memory T cell differentiation" EXACT [] +synonym: "inhibition of memory T cell differentiation" NARROW [] +synonym: "negative regulation of memory T cell development" RELATED [GOC:add] +synonym: "negative regulation of memory T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of memory T-cell differentiation" EXACT [] +synonym: "negative regulation of memory T-lymphocyte differentiation" EXACT [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0043380 ! regulation of memory T cell differentiation +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043379 ! memory T cell differentiation +relationship: negatively_regulates GO:0043379 ! memory T cell differentiation + +[Term] +id: GO:0043382 +name: positive regulation of memory T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of memory T cell differentiation." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of memory T cell differentiation" NARROW [] +synonym: "positive regulation of memory T cell development" RELATED [GOC:add] +synonym: "positive regulation of memory T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of memory T-cell differentiation" EXACT [] +synonym: "positive regulation of memory T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of memory T cell differentiation" NARROW [] +synonym: "up regulation of memory T cell differentiation" EXACT [] +synonym: "up-regulation of memory T cell differentiation" EXACT [] +synonym: "upregulation of memory T cell differentiation" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0043380 ! regulation of memory T cell differentiation +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043379 ! memory T cell differentiation +relationship: positively_regulates GO:0043379 ! memory T cell differentiation + +[Term] +id: GO:0043383 +name: negative T cell selection +namespace: biological_process +def: "The process of elimination of immature T cells which react strongly with self-antigens." [ISBN:0781735149, PMID:12414722] +synonym: "negative T lymphocyte selection" EXACT [] +synonym: "negative T-cell selection" EXACT [] +synonym: "negative T-lymphocyte selection" EXACT [] +is_a: GO:0045058 ! T cell selection + +[Term] +id: GO:0043384 +name: pre-T cell receptor complex +namespace: cellular_component +def: "A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins." [ISBN:0781735149, PMID:12220932] +synonym: "pre-T lymphocyte receptor complex" EXACT [] +synonym: "pre-T-cell receptor complex" EXACT [] +synonym: "pre-T-lymphocyte receptor complex" EXACT [] +synonym: "pre-TCR complex" EXACT [] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0043385 +name: mycotoxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus." [GOC:jl] +synonym: "mycotoxin metabolism" EXACT [] +is_a: GO:0009404 ! toxin metabolic process + +[Term] +id: GO:0043386 +name: mycotoxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus." [GOC:jl] +synonym: "mycotoxin anabolism" EXACT [] +synonym: "mycotoxin biosynthesis" EXACT [] +synonym: "mycotoxin formation" EXACT [] +synonym: "mycotoxin synthesis" EXACT [] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0043385 ! mycotoxin metabolic process + +[Term] +id: GO:0043387 +name: mycotoxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus." [GOC:jl] +synonym: "mycotoxin breakdown" EXACT [] +synonym: "mycotoxin catabolism" EXACT [] +synonym: "mycotoxin degradation" EXACT [] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0043385 ! mycotoxin metabolic process + +[Term] +id: GO:0043388 +name: positive regulation of DNA binding +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb] +synonym: "activation of DNA binding" NARROW [] +synonym: "stimulation of DNA binding" NARROW [] +synonym: "up regulation of DNA binding" EXACT [] +synonym: "up-regulation of DNA binding" EXACT [] +synonym: "upregulation of DNA binding" EXACT [] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003677 ! DNA binding +relationship: positively_regulates GO:0003677 ! DNA binding + +[Term] +id: GO:0043392 +name: negative regulation of DNA binding +namespace: biological_process +def: "Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb] +synonym: "down regulation of DNA binding" EXACT [] +synonym: "down-regulation of DNA binding" EXACT [] +synonym: "downregulation of DNA binding" EXACT [] +synonym: "inhibition of DNA binding" NARROW [] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003677 ! DNA binding +relationship: negatively_regulates GO:0003677 ! DNA binding + +[Term] +id: GO:0043393 +name: regulation of protein binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein binding." [GOC:go_curators] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005515 ! protein binding +relationship: regulates GO:0005515 ! protein binding + +[Term] +id: GO:0043394 +name: proteoglycan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [ISBN:0198506732] +is_a: GO:0005515 ! protein binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0043395 +name: heparan sulfate proteoglycan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit." [ISBN:0198506732] +synonym: "heparin proteoglycan binding" RELATED [] +is_a: GO:0043168 ! anion binding +is_a: GO:0043394 ! proteoglycan binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043396 +name: corticotropin-releasing hormone secretion +namespace: biological_process +def: "The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle." [GOC:go_curators, PMID:11027914] +synonym: "corticotropin-releasing factor secretion" EXACT [] +synonym: "CRF secretion" EXACT [] +synonym: "CRH secretion" EXACT [] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0043397 +name: regulation of corticotropin-releasing hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion." [GOC:go_curators, PMID:11027914] +synonym: "regulation of corticotropin-releasing factor secretion" EXACT [] +synonym: "regulation of CRF secretion" EXACT [] +synonym: "regulation of CRH secretion" EXACT [] +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043396 ! corticotropin-releasing hormone secretion +relationship: regulates GO:0043396 ! corticotropin-releasing hormone secretion + +[Term] +id: GO:0043398 +name: HLH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Helix Loop Helix, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization." [GOC:go_curators, Prosite:PDOC0038] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0043399 +name: tRNA A64-2'-O-ribosylphosphate transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA." [GOC:jl, PMID:7954819] +synonym: "initiator tRNA phosphoribosyl-transferase activity" EXACT [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0043400 +name: cortisol secretion +namespace: biological_process +def: "The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland." [PMID:11027914] +synonym: "hydrocortisone secretion" EXACT [CHEBI:17650] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport +is_a: GO:0035933 ! glucocorticoid secretion + +[Term] +id: GO:0043401 +name: steroid hormone mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by a steroid hormone binding to a receptor." [PMID:12606724] +synonym: "steroid hormone mediated signalling" EXACT [] +is_a: GO:0009755 ! hormone-mediated signaling pathway +relationship: part_of GO:0071383 ! cellular response to steroid hormone stimulus + +[Term] +id: GO:0043402 +name: glucocorticoid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of a glucocorticoid hormone." [PMID:15240347] +synonym: "glucocorticoid mediated signalling" EXACT [] +is_a: GO:0043401 ! steroid hormone mediated signaling pathway +relationship: part_of GO:0071385 ! cellular response to glucocorticoid stimulus + +[Term] +id: GO:0043403 +name: skeletal muscle tissue regeneration +namespace: biological_process +def: "The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage." [GOC:ef, GOC:mtg_muscle, PMID:12021255, PMID:16607119] +synonym: "myofiber turnover" RELATED [] +is_a: GO:0042246 ! tissue regeneration + +[Term] +id: GO:0043404 +name: corticotropin-releasing hormone receptor activity +namespace: molecular_function +alt_id: GO:0031636 +def: "Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity." [GOC:signaling, ISBN:0838577016, PMID:11027914, PMID:15134857] +synonym: "adrenocorticotropin-releasing hormone receptor activity" EXACT [] +synonym: "corticotropin-releasing factor receptor activity" EXACT [GOC:bf] +synonym: "CRF receptor activity" EXACT [GOC:bf] +synonym: "CRH receptor activity" EXACT [GOC:bf] +is_a: GO:0001653 ! peptide receptor activity +relationship: has_part GO:0051424 ! corticotropin-releasing hormone binding +relationship: part_of GO:0009755 ! hormone-mediated signaling pathway + +[Term] +id: GO:0043405 +name: regulation of MAP kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] +synonym: "Regulation of MAPK activity" EXACT [GOC:dph] +synonym: "regulation of mitogen activated protein kinase activity" EXACT [] +synonym: "regulation of mitogen-activated protein kinase activity" EXACT [] +is_a: GO:0043408 ! regulation of MAPK cascade +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004707 ! MAP kinase activity +relationship: regulates GO:0004707 ! MAP kinase activity + +[Term] +id: GO:0043406 +name: positive regulation of MAP kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] +synonym: "positive regulation of mitogen activated protein kinase activity" EXACT [] +synonym: "positive regulation of mitogen-activated protein kinase activity" EXACT [] +synonym: "stimulation of MAPK activity" NARROW [] +synonym: "up regulation of MAPK activity" EXACT [] +synonym: "up-regulation of MAPK activity" EXACT [] +synonym: "upregulation of MAPK activity" EXACT [] +is_a: GO:0043405 ! regulation of MAP kinase activity +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004707 ! MAP kinase activity +relationship: positively_regulates GO:0004707 ! MAP kinase activity + +[Term] +id: GO:0043407 +name: negative regulation of MAP kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] +synonym: "down regulation of MAPK activity" EXACT [] +synonym: "down-regulation of MAPK activity" EXACT [] +synonym: "downregulation of MAPK activity" EXACT [] +synonym: "inhibition of MAPK activity" NARROW [] +synonym: "negative regulation of mitogen activated protein kinase activity" EXACT [] +synonym: "negative regulation of mitogen-activated protein kinase activity" EXACT [] +is_a: GO:0043405 ! regulation of MAP kinase activity +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004707 ! MAP kinase activity +relationship: negatively_regulates GO:0004707 ! MAP kinase activity + +[Term] +id: GO:0043408 +name: regulation of MAPK cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade." [GOC:go_curators] +synonym: "regulation of MAP kinase cascade" EXACT [GOC:signaling] +synonym: "regulation of MAP kinase kinase kinase cascade" EXACT [] +synonym: "regulation of MAPKKK cascade" EXACT [GOC:signaling] +synonym: "regulation of mitogen activated protein kinase cascade" EXACT [GOC:signaling] +synonym: "regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] +synonym: "regulation of mitogen-activated protein kinase cascade" EXACT [GOC:signaling] +synonym: "regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000165 ! MAPK cascade +relationship: regulates GO:0000165 ! MAPK cascade + +[Term] +id: GO:0043409 +name: negative regulation of MAPK cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade." [GOC:go_curators] +synonym: "down regulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "down regulation of MAPKKK cascade" EXACT [] +synonym: "down-regulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "down-regulation of MAPKKK cascade" EXACT [] +synonym: "downregulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "downregulation of MAPKKK cascade" EXACT [] +synonym: "inhibition of MAPK cascade" NARROW [GOC:signaling] +synonym: "inhibition of MAPKKK cascade" NARROW [] +synonym: "negative regulation of MAP kinase cascade" EXACT [GOC:signaling] +synonym: "negative regulation of MAP kinase kinase kinase cascade" EXACT [] +synonym: "negative regulation of MAPKKK cascade" EXACT [GOC:signaling] +synonym: "negative regulation of mitogen activated protein kinase cascade" EXACT [GOC:signaling] +synonym: "negative regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] +synonym: "negative regulation of mitogen-activated protein kinase cascade" EXACT [GOC:signaling] +synonym: "negative regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0043408 ! regulation of MAPK cascade +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000165 ! MAPK cascade +relationship: negatively_regulates GO:0000165 ! MAPK cascade + +[Term] +id: GO:0043410 +name: positive regulation of MAPK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade." [GOC:go_curators] +synonym: "activation of MAPK cascade" NARROW [GOC:signaling] +synonym: "activation of MAPKKK cascade" NARROW [] +synonym: "positive regulation of MAP kinase cascade" EXACT [GOC:signaling] +synonym: "positive regulation of MAP kinase kinase kinase cascade" EXACT [] +synonym: "positive regulation of MAPKKK cascade" EXACT [GOC:signaling] +synonym: "positive regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] +synonym: "positive regulation of mitogen-activated protein kinase cascade" EXACT [GOC:signaling] +synonym: "positive regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] +synonym: "stimulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "stimulation of MAPKKK cascade" NARROW [] +synonym: "up regulation of MAPKKK cascade" EXACT [] +synonym: "up-regulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "up-regulation of MAPKKK cascade" EXACT [] +synonym: "upregulation of MAPK cascade" EXACT [GOC:signaling] +synonym: "upregulation of MAPKKK cascade" EXACT [] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0043408 ! regulation of MAPK cascade +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000165 ! MAPK cascade +relationship: positively_regulates GO:0000165 ! MAPK cascade + +[Term] +id: GO:0043411 +name: obsolete myopalladin binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with myopalladin, a myofibrillar protein with titin-like Ig domains." [GOC:go_curators] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "myopalladin binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0043412 +name: macromolecule modification +namespace: biological_process +def: "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." [GOC:go_curators] +subset: goslim_pir +is_a: GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0043413 +name: macromolecule glycosylation +namespace: biological_process +def: "The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." [GOC:jl] +is_a: GO:0043412 ! macromolecule modification +is_a: GO:0070085 ! glycosylation + +[Term] +id: GO:0043414 +name: macromolecule methylation +namespace: biological_process +def: "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." [GOC:go_curators] +is_a: GO:0032259 ! methylation +is_a: GO:0043412 ! macromolecule modification +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0043415 +name: positive regulation of skeletal muscle tissue regeneration +namespace: biological_process +def: "Any process that activates or increase the rate of skeletal muscle regeneration." [GOC:jl] +synonym: "activation of skeletal muscle regeneration" NARROW [] +synonym: "stimulation of skeletal muscle regeneration" NARROW [] +synonym: "up regulation of skeletal muscle regeneration" EXACT [] +synonym: "up-regulation of skeletal muscle regeneration" EXACT [] +synonym: "upregulation of skeletal muscle regeneration" EXACT [] +is_a: GO:0043416 ! regulation of skeletal muscle tissue regeneration +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0090303 ! positive regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043403 ! skeletal muscle tissue regeneration +relationship: positively_regulates GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0043416 +name: regulation of skeletal muscle tissue regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle." [GOC:jl] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043403 ! skeletal muscle tissue regeneration +relationship: regulates GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0043417 +name: negative regulation of skeletal muscle tissue regeneration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration." [GOC:jl] +synonym: "down regulation of skeletal muscle regeneration" EXACT [] +synonym: "down-regulation of skeletal muscle regeneration" EXACT [] +synonym: "downregulation of skeletal muscle regeneration" EXACT [] +synonym: "inhibition of skeletal muscle regeneration" NARROW [] +is_a: GO:0043416 ! regulation of skeletal muscle tissue regeneration +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0061045 ! negative regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043403 ! skeletal muscle tissue regeneration +relationship: negatively_regulates GO:0043403 ! skeletal muscle tissue regeneration + +[Term] +id: GO:0043418 +name: homocysteine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid." [GOC:jl] +synonym: "homocysteine breakdown" EXACT [] +synonym: "homocysteine catabolism" EXACT [] +synonym: "homocysteine degradation" EXACT [] +is_a: GO:0000098 ! sulfur amino acid catabolic process +is_a: GO:0050667 ! homocysteine metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0043419 +name: urea catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2." [GOC:jl] +synonym: "urea breakdown" EXACT [] +synonym: "urea catabolism" EXACT [] +synonym: "urea decomposition" EXACT [] +synonym: "urea degradation" EXACT [] +is_a: GO:0019627 ! urea metabolic process +is_a: GO:0043605 ! cellular amide catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0043420 +name: anthranilate metabolic process +namespace: biological_process +alt_id: GO:0018869 +def: "The chemical reactions and pathways involving anthranilate (2-aminobenzoate)." [GOC:jl] +synonym: "2-aminobenzoate metabolic process" EXACT [] +synonym: "2-aminobenzoate metabolism" EXACT [] +synonym: "anthranilate metabolism" EXACT [] +synonym: "anthranilic acid metabolic process" NARROW [] +synonym: "anthranilic acid metabolism" NARROW [] +synonym: "ortho-aminobenzoic acid metabolic process" NARROW [] +synonym: "ortho-aminobenzoic acid metabolism" NARROW [] +xref: UM-BBD_pathwayID:abz2 +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0043421 +name: anthranilate catabolic process +namespace: biological_process +alt_id: GO:0019259 +def: "The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate)." [GOC:jl] +synonym: "2-aminobenzoate breakdown" EXACT [] +synonym: "2-aminobenzoate catabolic process" EXACT [] +synonym: "2-aminobenzoate catabolism" NARROW [] +synonym: "2-aminobenzoate degradation" EXACT [] +synonym: "anthranilate breakdown" EXACT [] +synonym: "anthranilate catabolism" EXACT [] +synonym: "anthranilate degradation" EXACT [] +synonym: "anthranilic acid catabolic process" NARROW [] +synonym: "anthranilic acid catabolism" NARROW [] +synonym: "ortho-aminobenzoic acid catabolic process" NARROW [] +synonym: "ortho-aminobenzoic acid catabolism" NARROW [] +xref: MetaCyc:2AMINOBENZDEG-PWY +is_a: GO:0009074 ! aromatic amino acid family catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0043420 ! anthranilate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0043422 +name: protein kinase B binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism." [GOC:jl, http://www.heartandmetabolism.org/] +synonym: "Akt binding" EXACT [] +synonym: "PKB binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0043423 +name: 3-phosphoinositide-dependent protein kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 3-phosphoinositide-dependent protein kinase." [GOC:jl] +synonym: "phosphatidylinositol-3-phosphate-dependent protein kinase binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0043424 +name: protein histidine kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with protein histidine kinase." [GOC:jl] +synonym: "histidine kinase binding" EXACT [] +synonym: "histidine-protein kinase binding" EXACT [] +synonym: "protein-histidine kinase binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0043425 +name: bHLH transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways." [PMID:9144210] +is_a: GO:0140297 ! DNA-binding transcription factor binding + +[Term] +id: GO:0043426 +name: MRF binding +namespace: molecular_function +alt_id: GO:0051576 +alt_id: GO:0051577 +alt_id: GO:0051578 +alt_id: GO:0051579 +def: "Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors." [PMID:10966875] +synonym: "Mrf4 binding" NARROW [] +synonym: "Myf5 binding" NARROW [] +synonym: "MyoD binding" NARROW [] +synonym: "myogenin binding" NARROW [] +is_a: GO:0043425 ! bHLH transcription factor binding + +[Term] +id: GO:0043427 +name: carbon fixation by 3-hydroxypropionate cycle +namespace: biological_process +def: "An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product." [GOC:jl, PMID:11418572, PMID:15838028] +synonym: "3-hydroxypropionate cycle" EXACT [] +synonym: "3-hydroxypropionate pathway" EXACT [] +synonym: "hydroxypropionate cycle" EXACT [] +synonym: "hydroxypropionate pathway" EXACT [] +is_a: GO:0015977 ! carbon fixation + +[Term] +id: GO:0043428 +name: 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] +comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. +synonym: "2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] +xref: MetaCyc:RXN-9227 +is_a: GO:0008425 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + +[Term] +id: GO:0043429 +name: 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] +comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. +synonym: "2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] +is_a: GO:0008425 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + +[Term] +id: GO:0043430 +name: 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] +comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. +synonym: "2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] +xref: Reactome:R-HSA-2162188 "MDMQ10H2 is methylated to DMQ10H2 by COQ5" +is_a: GO:0008425 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + +[Term] +id: GO:0043431 +name: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838, PMID:1479344] +synonym: "2-octaprenyl-6-hydroxy phenol methylase activity" EXACT [] +synonym: "3-demethylubiquinone-9 3-methyltransferase activity" EXACT [] +xref: MetaCyc:2.1.1.64-RXN +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0043433 +name: negative regulation of DNA-binding transcription factor activity +namespace: biological_process +alt_id: GO:1904168 +alt_id: GO:2000824 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl] +synonym: "down regulation of transcription factor activity" EXACT [] +synonym: "down-regulation of transcription factor activity" EXACT [] +synonym: "downregulation of transcription factor activity" EXACT [] +synonym: "inhibition of transcription factor activity" NARROW [] +synonym: "negative regulation of androgen receptor activity" NARROW [] +synonym: "negative regulation of DNA binding transcription factor activity" EXACT [] +synonym: "negative regulation of sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "negative regulation of thyroid hormone receptor activity" NARROW [] +synonym: "negative regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0003700 ! DNA-binding transcription factor activity +relationship: negatively_regulates GO:0003700 ! DNA-binding transcription factor activity +creation_date: 2011-07-15T10:56:12Z + +[Term] +id: GO:0043434 +name: response to peptide hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone] +synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] +synonym: "response to polypeptide hormone stimulus" EXACT [] +is_a: GO:0009725 ! response to hormone +is_a: GO:1901652 ! response to peptide + +[Term] +id: GO:0043435 +name: response to corticotropin-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response." [PMID:11027914, PMID:15134857, Wikipedia:Corticotropin-releasing_hormone] +synonym: "response to corticoliberin stimulus" EXACT [] +synonym: "response to corticotropin-releasing factor stimulus" EXACT [] +synonym: "response to corticotropin-releasing hormone stimulus" EXACT [GOC:dos] +synonym: "response to CRF stimulus" EXACT [] +synonym: "response to CRH stimulus" EXACT [] +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0043436 +name: oxoacid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid] +synonym: "keto acid metabolic process" EXACT [] +synonym: "keto acid metabolism" EXACT [] +synonym: "ketoacid metabolic process" EXACT [] +synonym: "ketoacid metabolism" EXACT [] +synonym: "oxo acid metabolic process" EXACT [] +synonym: "oxo acid metabolism" EXACT [] +synonym: "oxoacid metabolism" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process + +[Term] +id: GO:0043438 +name: acetoacetic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH." [Wikipedia:Acetoacetic_acid] +synonym: "3-oxobutanoate metabolic process" EXACT [] +synonym: "3-oxobutanoate metabolism" EXACT [] +synonym: "3-oxobutanoic acid metabolic process" EXACT [] +synonym: "3-oxobutanoic acid metabolism" EXACT [] +synonym: "acetoacetate metabolic process" EXACT [] +synonym: "acetoacetate metabolism" EXACT [] +synonym: "acetoacetic acid metabolism" EXACT [] +synonym: "beta ketobutyric acid metabolic process" EXACT [] +synonym: "beta ketobutyric acid metabolism" EXACT [] +synonym: "beta-ketobutyric acid metabolic process" EXACT [] +synonym: "beta-ketobutyric acid metabolism" EXACT [] +synonym: "diacetic acid metabolic process" EXACT [] +synonym: "diacetic acid metabolism" EXACT [] +is_a: GO:0046459 ! short-chain fatty acid metabolic process +is_a: GO:1902224 ! ketone body metabolic process + +[Term] +id: GO:0043441 +name: acetoacetic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH." [GOC:jl] +synonym: "acetoacetic acid anabolism" EXACT [] +synonym: "acetoacetic acid biosynthesis" EXACT [] +synonym: "acetoacetic acid formation" EXACT [] +synonym: "acetoacetic acid synthesis" EXACT [] +is_a: GO:0043438 ! acetoacetic acid metabolic process +is_a: GO:0046951 ! ketone body biosynthetic process +is_a: GO:0051790 ! short-chain fatty acid biosynthetic process + +[Term] +id: GO:0043442 +name: acetoacetic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH." [GOC:jl] +synonym: "acetoacetic acid breakdown" EXACT [] +synonym: "acetoacetic acid catabolism" EXACT [] +synonym: "acetoacetic acid degradation" EXACT [] +is_a: GO:0019626 ! short-chain fatty acid catabolic process +is_a: GO:0043438 ! acetoacetic acid metabolic process +is_a: GO:0046952 ! ketone body catabolic process + +[Term] +id: GO:0043443 +name: acetone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetone, propan-2-one." [GOC:jl] +synonym: "2-propanone metabolic process" EXACT [] +synonym: "2-propanone metabolism" EXACT [] +synonym: "acetone metabolism" EXACT [] +synonym: "dimethyl ketone metabolic process" EXACT [] +synonym: "dimethyl ketone metabolism" EXACT [] +synonym: "propan-2-one metabolic process" EXACT [] +synonym: "propan-2-one metabolism" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902224 ! ketone body metabolic process + +[Term] +id: GO:0043444 +name: acetone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one." [GOC:jl] +synonym: "2-propanone catabolic process" EXACT [] +synonym: "2-propanone catabolism" EXACT [] +synonym: "acetone breakdown" EXACT [] +synonym: "acetone catabolism" EXACT [] +synonym: "acetone degradation" EXACT [] +synonym: "dimethyl ketone catabolic process" EXACT [] +synonym: "dimethyl ketone catabolism" EXACT [] +synonym: "propan-2-one catabolic process" EXACT [] +synonym: "propan-2-one catabolism" EXACT [] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0043443 ! acetone metabolic process +is_a: GO:0046952 ! ketone body catabolic process + +[Term] +id: GO:0043445 +name: acetone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetone, propan-2-one." [GOC:jl] +synonym: "2-propanone biosynthesis" EXACT [] +synonym: "2-propanone biosynthetic process" EXACT [] +synonym: "acetone anabolism" EXACT [] +synonym: "acetone biosynthesis" EXACT [] +synonym: "acetone formation" EXACT [] +synonym: "acetone synthesis" EXACT [] +synonym: "dimethyl ketone biosynthesis" EXACT [] +synonym: "dimethyl ketone biosynthetic process" EXACT [] +synonym: "propan-2-one biosynthesis" EXACT [] +synonym: "propan-2-one biosynthetic process" EXACT [] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0043443 ! acetone metabolic process +is_a: GO:0046951 ! ketone body biosynthetic process + +[Term] +id: GO:0043446 +name: cellular alkane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells." [GOC:jl, Wikipedia:Alkane] +subset: goslim_pir +synonym: "alkane metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0043447 +name: alkane biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." [GOC:jl, Wikipedia:Alkane] +synonym: "alkane anabolism" EXACT [] +synonym: "alkane biosynthesis" EXACT [] +synonym: "alkane formation" EXACT [] +synonym: "alkane synthesis" EXACT [] +is_a: GO:0043446 ! cellular alkane metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0043448 +name: alkane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2." [GOC:jl, Wikipedia:Alkane] +synonym: "alkane breakdown" EXACT [] +synonym: "alkane catabolism" EXACT [] +synonym: "alkane degradation" EXACT [] +is_a: GO:0043446 ! cellular alkane metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0043449 +name: cellular alkene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells." [GOC:jl, Wikipedia:Alkene] +subset: goslim_pir +synonym: "alkene metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:1900673 ! olefin metabolic process + +[Term] +id: GO:0043450 +name: alkene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n." [GOC:jl, Wikipedia:Alkene] +synonym: "alkene anabolism" EXACT [] +synonym: "alkene biosynthesis" EXACT [] +synonym: "alkene formation" EXACT [] +synonym: "alkene synthesis" EXACT [] +is_a: GO:0043449 ! cellular alkene metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1900674 ! olefin biosynthetic process + +[Term] +id: GO:0043451 +name: alkene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n." [GOC:jl, Wikipedia:Alkene] +synonym: "alkene breakdown" EXACT [] +synonym: "alkene catabolism" EXACT [] +synonym: "alkene degradation" EXACT [] +is_a: GO:0043449 ! cellular alkene metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0043452 +name: cellular alkyne metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an alkyne, any cyclic branched or unbranched hydrocarbon having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells." [GOC:jl, Wikipedia:Alkyne] +subset: goslim_pir +synonym: "alkyne metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0043453 +name: alkyne biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an alkyne, any cyclic branched or unbranched hydrocarbon having a carbon-carbon triple bond and the general formula CnH2n-2." [GOC:jl, Wikipedia:Alkyne] +synonym: "alkyne anabolism" EXACT [] +synonym: "alkyne biosynthesis" EXACT [] +synonym: "alkyne formation" EXACT [] +synonym: "alkyne synthesis" EXACT [] +is_a: GO:0043452 ! cellular alkyne metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0043454 +name: alkyne catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an alkyne, any cyclic branched or unbranched hydrocarbons having a carbon-carbon triple bond and the general formula CnH2n-2." [GOC:jl, Wikipedia:Alkyne] +synonym: "alkyne breakdown" EXACT [] +synonym: "alkyne catabolism" EXACT [] +synonym: "alkyne degradation" EXACT [] +is_a: GO:0043452 ! cellular alkyne metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0043455 +name: regulation of secondary metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] +synonym: "regulation of secondary metabolism" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019748 ! secondary metabolic process +relationship: regulates GO:0019748 ! secondary metabolic process + +[Term] +id: GO:0043456 +name: regulation of pentose-phosphate shunt +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis." [GOC:jl] +synonym: "regulation of pentose phosphate pathway" EXACT [] +synonym: "regulation of pentose phosphate shunt" EXACT [] +synonym: "regulation of pentose-phosphate pathway" EXACT [] +is_a: GO:0019220 ! regulation of phosphate metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:1902031 ! regulation of NADP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006098 ! pentose-phosphate shunt +relationship: regulates GO:0006098 ! pentose-phosphate shunt + +[Term] +id: GO:0043457 +name: regulation of cellular respiration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds." [GOC:jl] +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045333 ! cellular respiration +relationship: regulates GO:0045333 ! cellular respiration + +[Term] +id: GO:0043458 +name: ethanol biosynthetic process involved in glucose fermentation to ethanol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP." [GOC:dph, GOC:jl, GOC:tb] +synonym: "ethanol anabolism during fermentation" RELATED [] +synonym: "ethanol formation during fermentation" RELATED [] +synonym: "ethanol synthesis during fermentation" RELATED [] +is_a: GO:0006115 ! ethanol biosynthetic process +intersection_of: GO:0006115 ! ethanol biosynthetic process +intersection_of: part_of GO:0019655 ! glycolytic fermentation to ethanol +relationship: part_of GO:0019655 ! glycolytic fermentation to ethanol + +[Term] +id: GO:0043459 +name: obsolete response to short exposure to lithium ion +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus." [PMID:10208444] +comment: This term was made obsolete because 'short' is not a quantitative or meaningful measurement of time. +synonym: "response to short exposure to lithium ion" EXACT [] +is_obsolete: true + +[Term] +id: GO:0043460 +name: obsolete response to long exposure to lithium ion +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus." [PMID:10208444] +comment: This term was made obsolete because 'long' is not a quantitative or meaningful measurement of time. +synonym: "response to long exposure to lithium ion" EXACT [] +is_obsolete: true + +[Term] +id: GO:0043461 +name: proton-transporting ATP synthase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes." [GOC:jl, GOC:mah, http://www.mblab.gla.ac.uk/] +synonym: "F-type ATPase complex assembly" EXACT [] +is_a: GO:0070071 ! proton-transporting two-sector ATPase complex assembly + +[Term] +id: GO:0043462 +name: regulation of ATPase activity +namespace: biological_process +def: "Any process that modulates the rate of ATP hydrolysis by an ATPase." [GOC:jl] +synonym: "regulation of adenosinetriphosphatase activity" EXACT [] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016887 ! ATPase activity +relationship: regulates GO:0016887 ! ATPase activity + +[Term] +id: GO:0043463 +name: regulation of rhamnose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose." [GOC:jl] +synonym: "regulation of rhamnose breakdown" EXACT [] +synonym: "regulation of rhamnose catabolism" EXACT [] +synonym: "regulation of rhamnose degradation" EXACT [] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019301 ! rhamnose catabolic process +relationship: regulates GO:0019301 ! rhamnose catabolic process + +[Term] +id: GO:0043464 +name: malolactic fermentation +namespace: biological_process +def: "The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP." [PMID:10427020, PMID:8808948] +synonym: "L-malate fermentation" BROAD [] +synonym: "malate fermentation" BROAD [] +synonym: "malo-lactate fermentation" EXACT [] +synonym: "malolactate fermentation" EXACT [] +xref: Wikipedia:Malolactic_fermentation +is_a: GO:0006113 ! fermentation + +[Term] +id: GO:0043465 +name: regulation of fermentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)." [GOC:jl] +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006113 ! fermentation +relationship: regulates GO:0006113 ! fermentation + +[Term] +id: GO:0043466 +name: pyrimidine nucleobase fermentation +namespace: biological_process +def: "The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP." [GOC:jl] +synonym: "pyrimidine base fermentation" EXACT [GOC:go_curators] +synonym: "pyrimidine fermentation" RELATED [] +is_a: GO:0006208 ! pyrimidine nucleobase catabolic process +is_a: GO:0019666 ! nitrogenous compound fermentation + +[Term] +id: GO:0043467 +name: regulation of generation of precursor metabolites and energy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006091 ! generation of precursor metabolites and energy +relationship: regulates GO:0006091 ! generation of precursor metabolites and energy + +[Term] +id: GO:0043468 +name: regulation of fucose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose." [GOC:mlg] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019317 ! fucose catabolic process +relationship: regulates GO:0019317 ! fucose catabolic process + +[Term] +id: GO:0043469 +name: regulation of D-xylose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose." [GOC:mlg] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042843 ! D-xylose catabolic process +relationship: regulates GO:0042843 ! D-xylose catabolic process + +[Term] +id: GO:0043470 +name: regulation of carbohydrate catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0009894 ! regulation of catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016052 ! carbohydrate catabolic process +relationship: regulates GO:0016052 ! carbohydrate catabolic process + +[Term] +id: GO:0043471 +name: regulation of cellular carbohydrate catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells." [GOC:jl] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044275 ! cellular carbohydrate catabolic process +relationship: regulates GO:0044275 ! cellular carbohydrate catabolic process + +[Term] +id: GO:0043472 +name: IgD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an immunoglobulin of a D isotype." [PMID:12886015] +is_a: GO:0019865 ! immunoglobulin binding + +[Term] +id: GO:0043473 +name: pigmentation +namespace: biological_process +def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pir +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0043474 +name: pigment metabolic process involved in pigmentation +namespace: biological_process +def: "The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell." [GOC:dph, GOC:jl, GOC:tb] +synonym: "pigment metabolic process during pigmentation" RELATED [GOC:dph, GOC:tb] +synonym: "pigment metabolism during pigmentation" RELATED [] +is_a: GO:0042440 ! pigment metabolic process +intersection_of: GO:0042440 ! pigment metabolic process +intersection_of: part_of GO:0043473 ! pigmentation +relationship: part_of GO:0043473 ! pigmentation + +[Term] +id: GO:0043475 +name: pigment metabolic process involved in pigment accumulation +namespace: biological_process +def: "The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment." [GOC:jl] +synonym: "pigment metabolic process during pigment accumulation" RELATED [GOC:dph, GOC:tb] +synonym: "pigment metabolism during pigment accumulation" RELATED [] +is_a: GO:0043474 ! pigment metabolic process involved in pigmentation +intersection_of: GO:0042440 ! pigment metabolic process +intersection_of: part_of GO:0043476 ! pigment accumulation +relationship: part_of GO:0043476 ! pigment accumulation + +[Term] +id: GO:0043476 +name: pigment accumulation +namespace: biological_process +def: "The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus." [GOC:jl] +synonym: "pigment accumulation in response to external stimulus" EXACT [] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0043473 ! pigmentation + +[Term] +id: GO:0043477 +name: pigment biosynthetic process involved in pigment accumulation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation." [GOC:dph, GOC:jl, GOC:tb] +synonym: "pigment biosynthetic process during pigment accumulation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043475 ! pigment metabolic process involved in pigment accumulation +is_a: GO:0046148 ! pigment biosynthetic process +intersection_of: GO:0046148 ! pigment biosynthetic process +intersection_of: part_of GO:0043476 ! pigment accumulation + +[Term] +id: GO:0043478 +name: pigment accumulation in response to UV light +namespace: biological_process +def: "The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus." [GOC:jl] +is_a: GO:0009411 ! response to UV +is_a: GO:0043476 ! pigment accumulation + +[Term] +id: GO:0043479 +name: pigment accumulation in tissues in response to UV light +namespace: biological_process +def: "The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus." [GOC:jl] +is_a: GO:0043478 ! pigment accumulation in response to UV light +is_a: GO:0043480 ! pigment accumulation in tissues + +[Term] +id: GO:0043480 +name: pigment accumulation in tissues +namespace: biological_process +def: "The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus." [GOC:jl] +synonym: "organismal pigment accumulation" EXACT [] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0043476 ! pigment accumulation + +[Term] +id: GO:0043481 +name: anthocyanin accumulation in tissues in response to UV light +namespace: biological_process +def: "The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus." [GOC:jl] +is_a: GO:0043479 ! pigment accumulation in tissues in response to UV light + +[Term] +id: GO:0043482 +name: cellular pigment accumulation +namespace: biological_process +def: "The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus." [GOC:jl] +is_a: GO:0033059 ! cellular pigmentation +is_a: GO:0043476 ! pigment accumulation +is_a: GO:0051716 ! cellular response to stimulus + +[Term] +id: GO:0043483 +name: anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus." [GOC:dph, GOC:jl, GOC:tb] +synonym: "anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus" RELATED [] +synonym: "anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light" RELATED [GOC:dph, GOC:tb] +synonym: "anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus" RELATED [] +is_a: GO:0009718 ! anthocyanin-containing compound biosynthetic process +is_a: GO:0043477 ! pigment biosynthetic process involved in pigment accumulation +intersection_of: GO:0009718 ! anthocyanin-containing compound biosynthetic process +intersection_of: part_of GO:0043481 ! anthocyanin accumulation in tissues in response to UV light +relationship: part_of GO:0043481 ! anthocyanin accumulation in tissues in response to UV light + +[Term] +id: GO:0043484 +name: regulation of RNA splicing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." [GOC:jl] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008380 ! RNA splicing +relationship: regulates GO:0008380 ! RNA splicing + +[Term] +id: GO:0043485 +name: endosome to pigment granule transport +namespace: biological_process +def: "The directed movement of substances from endosomes to pigment granules." [GOC:jl] +is_a: GO:0046907 ! intracellular transport +relationship: part_of GO:0048757 ! pigment granule maturation + +[Term] +id: GO:0043486 +name: histone exchange +namespace: biological_process +def: "The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GOC:jl, PMID:11735001, PMID:15066277] +comment: Note that this term also includes the exchange of sperm-specific histones or protamines with histones, occurring during spermatogenesis and fertilization. +synonym: "histone chaperone" RELATED [GOC:vw] +synonym: "histone replacement" EXACT [] +is_a: GO:0034728 ! nucleosome organization +is_a: GO:0043044 ! ATP-dependent chromatin remodeling +relationship: has_part GO:0001207 ! histone displacement + +[Term] +id: GO:0043487 +name: regulation of RNA stability +namespace: biological_process +def: "Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs." [GOC:jl] +is_a: GO:0010608 ! posttranscriptional regulation of gene expression +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0051252 ! regulation of RNA metabolic process +is_a: GO:0065008 ! regulation of biological quality +relationship: regulates GO:0006401 ! RNA catabolic process + +[Term] +id: GO:0043488 +name: regulation of mRNA stability +namespace: biological_process +def: "Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs." [GOC:jl] +is_a: GO:0043487 ! regulation of RNA stability +is_a: GO:0061013 ! regulation of mRNA catabolic process + +[Term] +id: GO:0043489 +name: RNA stabilization +namespace: biological_process +def: "Prevention of degradation of RNA molecules." [GOC:go_curators] +is_a: GO:0043487 ! regulation of RNA stability +is_a: GO:1902369 ! negative regulation of RNA catabolic process + +[Term] +id: GO:0043490 +name: malate-aspartate shuttle +namespace: biological_process +def: "The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle." [GOC:jl, GOC:mtg_electron_transport, ISBN:0716743663] +synonym: "malate aspartate shuttle" EXACT [] +synonym: "malate/aspartate shuttle" EXACT [] +synonym: "malate:aspartate shuttle" EXACT [] +xref: Wikipedia:Malate-aspartate_shuttle +is_a: GO:1990542 ! mitochondrial transmembrane transport +relationship: part_of GO:0022904 ! respiratory electron transport chain + +[Term] +id: GO:0043491 +name: protein kinase B signaling +namespace: biological_process +def: "A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound." [GOC:bf, PMID:20517722] +synonym: "AKT signal transduction" EXACT [GOC:signaling] +synonym: "AKT signaling" EXACT [GOC:signaling] +synonym: "AKT signaling cascade" RELATED [] +synonym: "AKT signalling cascade" EXACT [] +synonym: "PKB signal transduction" EXACT [GOC:signaling] +synonym: "PKB signaling" EXACT [GOC:signaling] +synonym: "PKB signaling cascade" RELATED [] +synonym: "PKB signalling cascade" RELATED [] +synonym: "protein kinase B signal transduction" EXACT [GOC:signaling] +synonym: "protein kinase B signaling cascade" RELATED [GOC:signaling] +synonym: "protein kinase B signalling cascade" RELATED [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0043492 +name: ATPase activity, coupled to movement of substances +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance." [GOC:jl] +subset: gocheck_do_not_annotate +xref: Reactome:R-HSA-9033499 "PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol" +xref: Reactome:R-HSA-9033505 "PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12" +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0043493 +name: viral terminase complex +namespace: cellular_component +def: "A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides." [GOC:bf, GOC:bm, GOC:jl, GOC:mlg] +synonym: "phage terminase complex" NARROW [GOC:bm] +synonym: "virus terminase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0043494 +name: CLRC complex +namespace: cellular_component +def: "An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi." [GOC:vw, PMID:16127433, PMID:20211136] +synonym: "Clr4-Rik1-Cul4 complex" EXACT [] +synonym: "CLRC ubiquitin ligase complex" EXACT [] +synonym: "Rik1 E3 ubiquitin ligase complex" EXACT [] +synonym: "Rik1-E3 ubiquitin ligase complex" EXACT [] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +is_a: GO:0031465 ! Cul4B-RING E3 ubiquitin ligase complex +is_a: GO:0035097 ! histone methyltransferase complex + +[Term] +id: GO:0043495 +name: protein-membrane adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle." [GOC:go_curators] +synonym: "anchoring" RELATED [] +synonym: "protein membrane adaptor" EXACT [] +synonym: "protein membrane adaptor activity" EXACT [] +synonym: "protein membrane anchor" RELATED [] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19090 xsd:anyURI + +[Term] +id: GO:0043496 +name: regulation of protein homodimerization activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer." [GOC:jl, GOC:tb] +comment: Note that protein homodimerization is a molecular function: 'protein homodimerization activity ; GO:0042803'. +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042803 ! protein homodimerization activity +relationship: regulates GO:0042803 ! protein homodimerization activity + +[Term] +id: GO:0043497 +name: regulation of protein heterodimerization activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer." [GOC:jl, GOC:tb] +comment: Note that protein heterodimerization is a molecular function: 'protein heterodimerization activity ; GO:0046982'. +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046982 ! protein heterodimerization activity +relationship: regulates GO:0046982 ! protein heterodimerization activity + +[Term] +id: GO:0043498 +name: obsolete cell surface binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a cell." [GOC:jl] +comment: This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term. +synonym: "cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0003823 +consider: GO:0005102 +consider: GO:0007155 +consider: GO:0009986 +consider: GO:0046812 + +[Term] +id: GO:0043499 +name: obsolete eukaryotic cell surface binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a eukaryotic cell." [GOC:jl] +comment: This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term. +synonym: "eukaryotic cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0003823 +consider: GO:0005102 +consider: GO:0006952 +consider: GO:0009986 +consider: GO:0046812 + +[Term] +id: GO:0043500 +name: muscle adaptation +namespace: biological_process +def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] +subset: goslim_pir +synonym: "muscle plasticity" RELATED [] +is_a: GO:0003012 ! muscle system process +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0043501 +name: skeletal muscle adaptation +namespace: biological_process +def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] +synonym: "skeletal muscle plasticity" RELATED [] +is_a: GO:0014888 ! striated muscle adaptation + +[Term] +id: GO:0043502 +name: regulation of muscle adaptation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle] +synonym: "regulation of muscle plasticity" RELATED [] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0090257 ! regulation of muscle system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043500 ! muscle adaptation +relationship: regulates GO:0043500 ! muscle adaptation + +[Term] +id: GO:0043503 +name: skeletal muscle fiber adaptation +namespace: biological_process +def: "Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] +synonym: "skeletal muscle fiber plasticity" RELATED [] +synonym: "skeletal muscle fibre plasticity" EXACT [] +synonym: "skeletal myofiber plasticity" EXACT [] +synonym: "skeletal myofibre plasticity" EXACT [] +is_a: GO:0051716 ! cellular response to stimulus +relationship: part_of GO:0043501 ! skeletal muscle adaptation + +[Term] +id: GO:0043504 +name: mitochondrial DNA repair +namespace: biological_process +def: "The process of restoring mitochondrial DNA after damage." [PMID:12565799, PMID:15189144, PMID:16050976] +is_a: GO:0006281 ! DNA repair +is_a: GO:0032042 ! mitochondrial DNA metabolic process +intersection_of: GO:0006281 ! DNA repair +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0043505 +name: CENP-A containing nucleosome +namespace: cellular_component +def: "A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3)." [GOC:go_curators, PMID:15175412, PMID:16183641] +synonym: "CenH3 containing nucleosome" EXACT [] +synonym: "CENP-S-T-W-X" EXACT [GOC:vw, PMID:22304917] +synonym: "centromere specific nucleosome" RELATED [] +synonym: "centromere-specific nucleosome" RELATED [GOC:vw] +synonym: "centromeric nucleosome" RELATED [] +synonym: "CNP-T-W-S-X complex" EXACT [] +is_a: GO:0000786 ! nucleosome +relationship: part_of GO:0061638 ! CENP-A containing chromatin + +[Term] +id: GO:0043506 +name: regulation of JUN kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of JUN kinase activity." [GOC:jl] +synonym: "regulation of JUNK activity" EXACT [] +is_a: GO:0043405 ! regulation of MAP kinase activity +is_a: GO:0046328 ! regulation of JNK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004705 ! JUN kinase activity +relationship: regulates GO:0004705 ! JUN kinase activity +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0043507 +name: positive regulation of JUN kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of JUN kinase activity." [GOC:jl] +synonym: "positive regulation of JUNK activity" EXACT [] +synonym: "stimulation of JNK activity" NARROW [] +synonym: "up regulation of JNK activity" EXACT [] +synonym: "up-regulation of JNK activity" EXACT [] +synonym: "upregulation of JNK activity" EXACT [] +is_a: GO:0043406 ! positive regulation of MAP kinase activity +is_a: GO:0043506 ! regulation of JUN kinase activity +is_a: GO:0046330 ! positive regulation of JNK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004705 ! JUN kinase activity +relationship: positively_regulates GO:0004705 ! JUN kinase activity + +[Term] +id: GO:0043508 +name: negative regulation of JUN kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity." [GOC:jl] +synonym: "down regulation of JNK activity" EXACT [] +synonym: "down-regulation of JNK activity" EXACT [] +synonym: "downregulation of JNK activity" EXACT [] +synonym: "inhibition of JNK activity" NARROW [] +synonym: "negative regulation of JUNK activity" EXACT [] +is_a: GO:0043407 ! negative regulation of MAP kinase activity +is_a: GO:0043506 ! regulation of JUN kinase activity +is_a: GO:0046329 ! negative regulation of JNK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004705 ! JUN kinase activity +relationship: negatively_regulates GO:0004705 ! JUN kinase activity + +[Term] +id: GO:0043509 +name: activin A complex +namespace: cellular_component +alt_id: GO:0048181 +def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A)." [GOC:go_curators] +comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'. +is_a: GO:0048180 ! activin complex + +[Term] +id: GO:0043510 +name: activin B complex +namespace: cellular_component +alt_id: GO:0048182 +def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B)." [GOC:go_curators] +comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. +is_a: GO:0048180 ! activin complex + +[Term] +id: GO:0043511 +name: inhibin complex +namespace: cellular_component +def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B." [GOC:jl] +comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0043512 +name: inhibin A complex +namespace: cellular_component +def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit." [GOC:jl] +comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. +is_a: GO:0043511 ! inhibin complex + +[Term] +id: GO:0043513 +name: inhibin B complex +namespace: cellular_component +def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit." [GOC:jl] +comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. +is_a: GO:0043511 ! inhibin complex + +[Term] +id: GO:0043514 +name: interleukin-12 complex +namespace: cellular_component +def: "A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space." [GOC:add, GOC:ebc, GOC:mah, PMID:12948519, PMID:1381512] +comment: Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain. +synonym: "IL-12 complex" EXACT [GOC:mah] +synonym: "IL12A" NARROW [GOC:add] +synonym: "IL12B" NARROW [GOC:add] +synonym: "p35" NARROW [GOC:add] +synonym: "p40" NARROW [GOC:add] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0043515 +name: kinetochore binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached." [GOC:jl, http://www.mercksource.com/] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0043516 +name: regulation of DNA damage response, signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] +synonym: "regulation of p53 induced by DNA damage response" EXACT [] +is_a: GO:1901796 ! regulation of signal transduction by p53 class mediator +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator +relationship: regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator + +[Term] +id: GO:0043517 +name: positive regulation of DNA damage response, signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] +synonym: "activation of DNA damage response, signal transduction by p53 class mediator" NARROW [] +synonym: "positive regulation of p53 induced by DNA damage response" EXACT [] +synonym: "stimulation of DNA damage response, signal transduction by p53 class mediator" NARROW [] +synonym: "up regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +synonym: "up-regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +synonym: "upregulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +is_a: GO:0043516 ! regulation of DNA damage response, signal transduction by p53 class mediator +is_a: GO:1901798 ! positive regulation of signal transduction by p53 class mediator +is_a: GO:2001022 ! positive regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator +relationship: positively_regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator + +[Term] +id: GO:0043518 +name: negative regulation of DNA damage response, signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] +synonym: "down regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +synonym: "down-regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +synonym: "downregulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] +synonym: "inhibition of DNA damage response, signal transduction by p53 class mediator" NARROW [] +synonym: "negative regulation of p53 induced by DNA damage response" EXACT [] +is_a: GO:0043516 ! regulation of DNA damage response, signal transduction by p53 class mediator +is_a: GO:1901797 ! negative regulation of signal transduction by p53 class mediator +is_a: GO:2001021 ! negative regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator +relationship: negatively_regulates GO:0030330 ! DNA damage response, signal transduction by p53 class mediator + +[Term] +id: GO:0043519 +name: regulation of myosin II filament organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules." [GOC:jl] +synonym: "regulation of myosin II filament assembly or disassembly" RELATED [GOC:mah] +synonym: "regulation of myosin II filament organisation" EXACT [GOC:mah] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031038 ! myosin II filament organization +relationship: regulates GO:0031038 ! myosin II filament organization + +[Term] +id: GO:0043520 +name: regulation of myosin II filament assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules." [GOC:jl] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0043519 ! regulation of myosin II filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031036 ! myosin II filament assembly +relationship: regulates GO:0031036 ! myosin II filament assembly + +[Term] +id: GO:0043521 +name: regulation of myosin II filament disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules." [GOC:jl] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +is_a: GO:0043519 ! regulation of myosin II filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031037 ! myosin II filament disassembly +relationship: regulates GO:0031037 ! myosin II filament disassembly + +[Term] +id: GO:0043522 +name: leucine zipper domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns." [GOC:jl, InterPro:IPR002158] +synonym: "leucine zipper binding" EXACT [] +is_a: GO:0030275 ! LRR domain binding + +[Term] +id: GO:0043523 +name: regulation of neuron apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "regulation of apoptosis of neuronal cells" EXACT [] +synonym: "regulation of apoptosis of neurons" EXACT [] +synonym: "regulation of neuron apoptosis" NARROW [] +synonym: "regulation of neuron programmed cell death" EXACT [] +synonym: "regulation of neuronal cell programmed cell death" EXACT [] +synonym: "regulation of programmed cell death of neuronal cells" EXACT [] +synonym: "regulation of programmed cell death, neurons" EXACT [] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:1901214 ! regulation of neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051402 ! neuron apoptotic process +relationship: regulates GO:0051402 ! neuron apoptotic process + +[Term] +id: GO:0043524 +name: negative regulation of neuron apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "down regulation of neuron apoptosis" EXACT [] +synonym: "down-regulation of neuron apoptosis" EXACT [] +synonym: "downregulation of neuron apoptosis" EXACT [] +synonym: "inhibition of neuron apoptosis" NARROW [] +synonym: "negative regulation of neuron apoptosis" NARROW [] +synonym: "negative regulation of programmed cell death, neurons" EXACT [] +synonym: "neuron survival" NARROW [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:0043523 ! regulation of neuron apoptotic process +is_a: GO:1901215 ! negative regulation of neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051402 ! neuron apoptotic process +relationship: negatively_regulates GO:0051402 ! neuron apoptotic process + +[Term] +id: GO:0043525 +name: positive regulation of neuron apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "activation of neuron apoptosis" NARROW [] +synonym: "positive regulation of neuron apoptosis" NARROW [] +synonym: "positive regulation of programmed cell death, neurons" EXACT [] +synonym: "stimulation of neuron apoptosis" NARROW [] +synonym: "up regulation of neuron apoptosis" EXACT [] +synonym: "up-regulation of neuron apoptosis" EXACT [] +synonym: "upregulation of neuron apoptosis" EXACT [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0043523 ! regulation of neuron apoptotic process +is_a: GO:1901216 ! positive regulation of neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051402 ! neuron apoptotic process +relationship: positively_regulates GO:0051402 ! neuron apoptotic process + +[Term] +id: GO:0043526 +name: obsolete neuroprotection +namespace: biological_process +def: "OBSOLETE. Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss." [GOC:mtg_apoptosis, MSH:D017209, PMID:10208444, PMID:11909981, PMID:15905876] +comment: This term was made obsolete because it refers to assays rather than processes. If neuron death by apoptosis is assessed, consider using GO:0043523 regulation of neuron apoptotic process. If neuron death is assessed but the cell death modality isn't defined, refer to GO:0070997 neuron death. Where non-neuronal cells are involved, and/or processes other than cell death are described, please use other terms for annotation. +synonym: "neuroprotection" EXACT [] +xref: Wikipedia:Neuroprotection +is_obsolete: true + +[Term] +id: GO:0043527 +name: tRNA methyltransferase complex +namespace: cellular_component +def: "A multimeric protein complex involved in the methylation of specific nucleotides in tRNA." [GOC:jl, PMID:24904644, PMID:9851972] +subset: goslim_pir +is_a: GO:0034708 ! methyltransferase complex + +[Term] +id: GO:0043528 +name: tRNA (m2G10) methyltransferase complex +namespace: cellular_component +def: "A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p." [PMID:15899842] +is_a: GO:0043527 ! tRNA methyltransferase complex + +[Term] +id: GO:0043529 +name: GET complex +namespace: cellular_component +def: "A multisubunit complex involved in ER/Golgi trafficking (Golgi to ER Traffic). In yeast, includes Get1p, Get2p and Get3p proteins." [PMID:16269340] +synonym: "Golgi to ER Traffic complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0043530 +name: adenosine 5'-monophosphoramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine 5'-monophosphoramidate = AMP + NH2. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester." [PMID:11805111] +synonym: "adenosine 5' monophosphoramidase activity" EXACT [] +synonym: "adenosine 5'-monophosphoramidate hydrolase activity" EXACT [] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0043531 +name: ADP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate." [GOC:jl] +synonym: "adenosine 5'-diphosphate binding" EXACT [] +synonym: "adenosine diphosphate binding" EXACT [] +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0043532 +name: angiostatin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis." [PMID:16043488] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0043533 +name: inositol 1,3,4,5 tetrakisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with inositol 1,3,4,5 tetrakisphosphate." [GOC:go_curators] +synonym: "InsP4 binding" EXACT [] +synonym: "IP4 binding" EXACT [] +is_a: GO:0043168 ! anion binding +is_a: GO:0043178 ! alcohol binding + +[Term] +id: GO:0043534 +name: blood vessel endothelial cell migration +namespace: biological_process +def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264] +is_a: GO:0043542 ! endothelial cell migration + +[Term] +id: GO:0043535 +name: regulation of blood vessel endothelial cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] +is_a: GO:0010594 ! regulation of endothelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043534 ! blood vessel endothelial cell migration +relationship: regulates GO:0043534 ! blood vessel endothelial cell migration + +[Term] +id: GO:0043536 +name: positive regulation of blood vessel endothelial cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] +synonym: "activation of blood vessel endothelial cell migration" NARROW [] +synonym: "stimulation of blood vessel endothelial cell migration" NARROW [] +synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] +synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] +synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] +is_a: GO:0010595 ! positive regulation of endothelial cell migration +is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043534 ! blood vessel endothelial cell migration +relationship: positively_regulates GO:0043534 ! blood vessel endothelial cell migration + +[Term] +id: GO:0043537 +name: negative regulation of blood vessel endothelial cell migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] +synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] +synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] +synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] +synonym: "inhibition of blood vessel endothelial cell migration" NARROW [] +is_a: GO:0010596 ! negative regulation of endothelial cell migration +is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration +relationship: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration + +[Term] +id: GO:0043538 +name: regulation of actin phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule." [GOC:go_curators] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031289 ! actin phosphorylation +relationship: regulates GO:0031289 ! actin phosphorylation + +[Term] +id: GO:0043539 +name: protein serine/threonine kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a protein serine/threonine kinase." [GOC:go_curators] +synonym: "protein ser/thr kinase activator activity" EXACT [] +is_a: GO:0030295 ! protein kinase activator activity +relationship: part_of GO:0071902 ! positive regulation of protein serine/threonine kinase activity + +[Term] +id: GO:0043540 +name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex +namespace: cellular_component +def: "A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis." [GOC:jl, GOC:so] +comment: Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future. +synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex" NARROW [] +synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex" NARROW [] +synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex" NARROW [] +synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex" NARROW [] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0043541 +name: UDP-N-acetylglucosamine transferase complex +namespace: cellular_component +def: "A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis." [GOC:rn, PMID:19129246] +comment: See also the molecular function term 'N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ; GO:0004577'. +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane + +[Term] +id: GO:0043542 +name: endothelial cell migration +namespace: biological_process +def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators] +is_a: GO:0010631 ! epithelial cell migration + +[Term] +id: GO:0043543 +name: protein acylation +namespace: biological_process +def: "The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid." [GOC:jl] +subset: goslim_yeast +synonym: "protein amino acid acylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0043544 +name: lipoamide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group." [GOC:go_curators] +is_a: GO:0033218 ! amide binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043545 +name: molybdopterin cofactor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [ISSN:09498257] +synonym: "Moco metabolic process" EXACT [] +synonym: "Moco metabolism" EXACT [] +synonym: "molybdopterin cofactor metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0051189 ! prosthetic group metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0043546 +name: molybdopterin cofactor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [ISSN:09498257] +synonym: "Moco binding" EXACT [] +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0043547 +name: positive regulation of GTPase activity +namespace: biological_process +alt_id: GO:0032320 +alt_id: GO:0032321 +alt_id: GO:0032850 +alt_id: GO:0032851 +alt_id: GO:0032852 +alt_id: GO:0032853 +alt_id: GO:0032854 +alt_id: GO:0032855 +alt_id: GO:0043089 +def: "Any process that activates or increases the activity of a GTPase." [GOC:jl, GOC:mah] +synonym: "activation of GTPase activity" NARROW [] +synonym: "positive regulation of ARF GTPase activity" NARROW [] +synonym: "positive regulation of Cdc42 GTPase activity" NARROW [] +synonym: "positive regulation of Rab GTPase activity" NARROW [] +synonym: "positive regulation of Rac GTPase activity" NARROW [] +synonym: "positive regulation of Ral GTPase activity" NARROW [] +synonym: "positive regulation of Ran GTPase activity" NARROW [] +synonym: "positive regulation of Rap GTPase activity" NARROW [] +synonym: "positive regulation of Ras GTPase activity" NARROW [] +synonym: "positive regulation of Rho GTPase activity" NARROW [] +synonym: "stimulation of ARF GTPase activity" NARROW [] +synonym: "stimulation of Cdc42 GTPase activity" NARROW [] +synonym: "stimulation of GTPase activity" NARROW [] +synonym: "stimulation of Rab GTPase activity" NARROW [] +synonym: "stimulation of Rac GTPase activity" NARROW [] +synonym: "stimulation of Ral GTPase activity" NARROW [] +synonym: "stimulation of Ran GTPase activity" NARROW [] +synonym: "stimulation of Rap GTPase activity" NARROW [] +synonym: "stimulation of Ras GTPase activity" NARROW [] +synonym: "stimulation of Rho GTPase activity" NARROW [] +synonym: "up regulation of ARF GTPase activity" NARROW [] +synonym: "up regulation of Cdc42 GTPase activity" NARROW [] +synonym: "up regulation of GTPase activity" EXACT [] +synonym: "up regulation of Rab GTPase activity" NARROW [] +synonym: "up regulation of Rac GTPase activity" NARROW [] +synonym: "up regulation of Ral GTPase activity" NARROW [] +synonym: "up regulation of Ran GTPase activity" NARROW [] +synonym: "up regulation of Rap GTPase activity" NARROW [] +synonym: "up regulation of Ras GTPase activity" NARROW [] +synonym: "up regulation of Rho GTPase activity" NARROW [] +synonym: "up-regulation of ARF GTPase activity" NARROW [] +synonym: "up-regulation of Cdc42 GTPase activity" NARROW [] +synonym: "up-regulation of GTPase activity" EXACT [] +synonym: "up-regulation of Rab GTPase activity" NARROW [] +synonym: "up-regulation of Rac GTPase activity" NARROW [] +synonym: "up-regulation of Ral GTPase activity" NARROW [] +synonym: "up-regulation of Ran GTPase activity" NARROW [] +synonym: "up-regulation of Rap GTPase activity" NARROW [] +synonym: "up-regulation of Ras GTPase activity" NARROW [] +synonym: "up-regulation of Rho GTPase activity" NARROW [] +synonym: "upregulation of ARF GTPase activity" NARROW [] +synonym: "upregulation of Cdc42 GTPase activity" NARROW [] +synonym: "upregulation of GTPase activity" EXACT [] +synonym: "upregulation of Rab GTPase activity" NARROW [] +synonym: "upregulation of Rac GTPase activity" NARROW [] +synonym: "upregulation of Ral GTPase activity" NARROW [] +synonym: "upregulation of Ran GTPase activity" NARROW [] +synonym: "upregulation of Rap GTPase activity" NARROW [] +synonym: "upregulation of Ras GTPase activity" NARROW [] +synonym: "upregulation of Rho GTPase activity" NARROW [] +is_a: GO:0043087 ! regulation of GTPase activity +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003924 ! GTPase activity +relationship: positively_regulates GO:0003924 ! GTPase activity + +[Term] +id: GO:0043548 +name: phosphatidylinositol 3-kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring." [PMID:10209156, PMID:9255069] +synonym: "phosphoinositide 3-kinase binding" EXACT [] +synonym: "PI3K binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0043549 +name: regulation of kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf] +is_a: GO:0042325 ! regulation of phosphorylation +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016301 ! kinase activity +relationship: regulates GO:0016301 ! kinase activity + +[Term] +id: GO:0043550 +name: regulation of lipid kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." [GOC:bf] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001727 ! lipid kinase activity +relationship: regulates GO:0001727 ! lipid kinase activity + +[Term] +id: GO:0043551 +name: regulation of phosphatidylinositol 3-kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring." [GOC:bf] +synonym: "regulation of phosphoinositide 3-kinase activity" EXACT [] +is_a: GO:0043550 ! regulation of lipid kinase activity +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035004 ! phosphatidylinositol 3-kinase activity +relationship: regulates GO:0035004 ! phosphatidylinositol 3-kinase activity + +[Term] +id: GO:0043552 +name: positive regulation of phosphatidylinositol 3-kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity." [GOC:bf] +synonym: "activation of phosphatidylinositol 3-kinase activity" NARROW [] +synonym: "positive regulation of phosphoinositide 3-kinase activity" EXACT [] +synonym: "stimulation of phosphatidylinositol 3-kinase activity" NARROW [] +synonym: "up regulation of phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "up-regulation of phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "upregulation of phosphatidylinositol 3-kinase activity" EXACT [] +is_a: GO:0043551 ! regulation of phosphatidylinositol 3-kinase activity +is_a: GO:0090218 ! positive regulation of lipid kinase activity +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035004 ! phosphatidylinositol 3-kinase activity +relationship: positively_regulates GO:0035004 ! phosphatidylinositol 3-kinase activity + +[Term] +id: GO:0043553 +name: negative regulation of phosphatidylinositol 3-kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity." [GOC:bf] +synonym: "down regulation of phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "down-regulation of phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "downregulation of phosphatidylinositol 3-kinase activity" EXACT [] +synonym: "inhibition of phosphatidylinositol 3-kinase activity" NARROW [] +synonym: "negative regulation of phosphoinositide 3-kinase activity" EXACT [] +synonym: "negative regulation of PI3K activity" EXACT [GOC:bf] +is_a: GO:0043551 ! regulation of phosphatidylinositol 3-kinase activity +is_a: GO:0090219 ! negative regulation of lipid kinase activity +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035004 ! phosphatidylinositol 3-kinase activity +relationship: negatively_regulates GO:0035004 ! phosphatidylinositol 3-kinase activity + +[Term] +id: GO:0043554 +name: aerobic respiration, using arsenite as electron donor +namespace: biological_process +def: "The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems." [GOC:mlg] +is_a: GO:0009060 ! aerobic respiration +is_a: GO:0015975 ! energy derivation by oxidation of reduced inorganic compounds + +[Term] +id: GO:0043555 +name: regulation of translation in response to stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] +synonym: "translational stress response" EXACT [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0043556 +name: regulation of translation in response to oxidative stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl] +is_a: GO:0043555 ! regulation of translation in response to stress +relationship: part_of GO:0034599 ! cellular response to oxidative stress + +[Term] +id: GO:0043557 +name: regulation of translation in response to osmotic stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:jl] +is_a: GO:0006970 ! response to osmotic stress +is_a: GO:0043555 ! regulation of translation in response to stress + +[Term] +id: GO:0043558 +name: regulation of translational initiation in response to stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." [GOC:jl] +synonym: "regulation of translation initiation in response to stress" EXACT [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0043555 ! regulation of translation in response to stress + +[Term] +id: GO:0043559 +name: insulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [ISBN:0198506732] +is_a: GO:0005515 ! protein binding +is_a: GO:0017046 ! peptide hormone binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0043560 +name: insulin receptor substrate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex." [PMID:12829233] +synonym: "insulin receptor substrate [protein] binding" EXACT [] +synonym: "IRS [protein] binding" EXACT [] +synonym: "IRS binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0043561 +name: regulation of translational initiation in response to osmotic stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, GOC:jl, GOC:tb] +is_a: GO:0043557 ! regulation of translation in response to osmotic stress +is_a: GO:0043558 ! regulation of translational initiation in response to stress + +[Term] +id: GO:0043562 +name: cellular response to nitrogen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen." [GOC:jl] +is_a: GO:0031669 ! cellular response to nutrient levels + +[Term] +id: GO:0043563 +name: obsolete odorant transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells." [GOC:jl] +is_obsolete: true + +[Term] +id: GO:0043564 +name: Ku70:Ku80 complex +namespace: cellular_component +def: "Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK." [PMID:12518983] +synonym: "Ku70:Ku80 heterodimer" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0043565 +name: sequence-specific DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl] +synonym: "sequence specific DNA binding" EXACT [] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0043567 +name: regulation of insulin-like growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] +synonym: "regulation of IGF receptor signaling pathway" EXACT [] +synonym: "regulation of IGF receptor signalling pathway" EXACT [] +synonym: "regulation of insulin-like growth factor receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway +relationship: regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway + +[Term] +id: GO:0043568 +name: positive regulation of insulin-like growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] +synonym: "activation of insulin-like growth factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of IGF receptor signaling pathway" EXACT [] +synonym: "positive regulation of IGF receptor signalling pathway" EXACT [] +synonym: "positive regulation of insulin-like growth factor receptor signalling pathway" EXACT [] +synonym: "stimulation of insulin-like growth factor receptor signaling pathway" NARROW [] +synonym: "up regulation of insulin-like growth factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of insulin-like growth factor receptor signaling pathway" EXACT [] +synonym: "upregulation of insulin-like growth factor receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0043567 ! regulation of insulin-like growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway +relationship: positively_regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway + +[Term] +id: GO:0043569 +name: negative regulation of insulin-like growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] +synonym: "down regulation of insulin-like growth factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of insulin-like growth factor receptor signaling pathway" EXACT [] +synonym: "downregulation of insulin-like growth factor receptor signaling pathway" EXACT [] +synonym: "inhibition of insulin-like growth factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of IGF receptor signaling pathway" EXACT [] +synonym: "negative regulation of IGF receptor signalling pathway" EXACT [] +synonym: "negative regulation of insulin-like growth factor receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0043567 ! regulation of insulin-like growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway +relationship: negatively_regulates GO:0048009 ! insulin-like growth factor receptor signaling pathway + +[Term] +id: GO:0043570 +name: maintenance of DNA repeat elements +namespace: biological_process +def: "Any process involved in sustaining the fidelity and copy number of DNA repeat elements." [GOC:jl] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0043571 +name: maintenance of CRISPR repeat elements +namespace: biological_process +def: "Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences." [PMID:16292354] +synonym: "CRISPR element metabolic process" RELATED [] +synonym: "CRISPR element metabolism" RELATED [] +synonym: "maintenance of clustered regularly interspaced short palindromic repeat elements" EXACT [] +is_a: GO:0043570 ! maintenance of DNA repeat elements + +[Term] +id: GO:0043572 +name: plastid fission +namespace: biological_process +def: "The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA." [GOC:jl] +is_a: GO:0048285 ! organelle fission + +[Term] +id: GO:0043573 +name: leucoplast fission +namespace: biological_process +def: "The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes." [GOC:jl] +is_a: GO:0043572 ! plastid fission + +[Term] +id: GO:0043574 +name: peroxisomal transport +namespace: biological_process +def: "Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:jl] +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0043575 +name: detection of osmotic stimulus +namespace: biological_process +def: "The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal." [GOC:jl] +is_a: GO:0006970 ! response to osmotic stress +is_a: GO:0009582 ! detection of abiotic stimulus + +[Term] +id: GO:0043576 +name: regulation of respiratory gaseous exchange +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system +relationship: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system + +[Term] +id: GO:0043577 +name: chemotropism +namespace: biological_process +def: "The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it." [GOC:jl, PMID:10087613] +xref: Wikipedia:Chemotropism +is_a: GO:0009606 ! tropism +intersection_of: GO:0009606 ! tropism +intersection_of: part_of GO:0042221 ! response to chemical +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0043578 +name: nuclear matrix organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane." [GOC:dph, GOC:jl, GOC:mah] +synonym: "nuclear matrix organisation" EXACT [] +synonym: "nuclear matrix organization and biogenesis" RELATED [GOC:mah] +synonym: "nucleoskeleton organization" EXACT [GOC:tb] +is_a: GO:0006997 ! nucleus organization + +[Term] +id: GO:0043579 +name: elaioplast organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored." [GOC:jl] +synonym: "elaioplast organisation" EXACT [] +synonym: "elaioplast organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0009659 ! leucoplast organization + +[Term] +id: GO:0043580 +name: periplasmic space organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi." [GOC:dph, GOC:jl, GOC:mah] +synonym: "periplasmic space organisation" EXACT [GOC:mah] +synonym: "periplasmic space organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0043581 +name: obsolete mycelium development +namespace: biological_process +def: "OBSOLETE. The process whose specific outcome is the progression of the mycelium over time, from its formation to the mature structure. A mycelium consists of a mass of branching, thread-like hyphae." [GOC:jl, ISBN:1580085792, PMID:12832397] +comment: The reason for obsoletion is that the term is ambiguous. Three more clearly defined terms have been created that should be considered in its place. +is_obsolete: true +consider: GO:0097736 +consider: GO:0097737 +consider: GO:0097738 + +[Term] +id: GO:0043582 +name: sporangium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores." [GOC:jl, Wikipedia:Sporagium] +synonym: "sporangia development" EXACT [] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0043583 +name: ear development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] +synonym: "hearing organ development" EXACT [] +is_a: GO:0007423 ! sensory organ development + +[Term] +id: GO:0043584 +name: nose development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl, http://www.mercksource.com/] +synonym: "nasus development" EXACT [] +is_a: GO:0007423 ! sensory organ development +relationship: part_of GO:0060541 ! respiratory system development + +[Term] +id: GO:0043585 +name: nose morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl, http://www.mercksource.com/] +synonym: "nasus morphogenesis" EXACT [] +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0043584 ! nose development + +[Term] +id: GO:0043586 +name: tongue development +namespace: biological_process +def: "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] +synonym: "glossa development" NARROW [] +synonym: "lingua development" NARROW [] +is_a: GO:0007423 ! sensory organ development + +[Term] +id: GO:0043587 +name: tongue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] +synonym: "glossa morphogenesis" NARROW [] +synonym: "lingua morphogenesis" EXACT [] +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0043586 ! tongue development + +[Term] +id: GO:0043588 +name: skin development +namespace: biological_process +def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] +synonym: "animal skin development" EXACT [] +is_a: GO:0048513 ! animal organ development +property_value: RO:0002161 NCBITaxon:50557 + +[Term] +id: GO:0043589 +name: skin morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0043588 ! skin development + +[Term] +id: GO:0043590 +name: bacterial nucleoid +namespace: cellular_component +def: "The region of a bacterial cell to which the DNA is confined." [GOC:jl] +is_a: GO:0009295 ! nucleoid +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0043591 +name: endospore external encapsulating structure +namespace: cellular_component +alt_id: GO:0055030 +def: "The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer." [GOC:go_curators, PMID:15035041] +subset: goslim_pir +synonym: "endospore wall" EXACT [GOC:mah] +synonym: "peptidoglycan-based spore wall" EXACT [GOC:mtg_sensu] +synonym: "spore wall" BROAD [GOC:mtg_sensu] +is_a: GO:0031160 ! spore wall + +[Term] +id: GO:0043592 +name: exosporium +namespace: cellular_component +def: "The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid." [GOC:mlg] +synonym: "epispore" RELATED [] +synonym: "exospore" RELATED [] +synonym: "perispore" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043591 ! endospore external encapsulating structure + +[Term] +id: GO:0043593 +name: endospore coat +namespace: cellular_component +def: "The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination." [GOC:mlg] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043591 ! endospore external encapsulating structure + +[Term] +id: GO:0043594 +name: outer endospore membrane +namespace: cellular_component +def: "The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat." [GOC:mlg] +is_a: GO:0019867 ! outer membrane +intersection_of: GO:0019867 ! outer membrane +intersection_of: part_of GO:0043591 ! endospore external encapsulating structure +relationship: part_of GO:0043591 ! endospore external encapsulating structure + +[Term] +id: GO:0043595 +name: endospore cortex +namespace: cellular_component +def: "A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan." [GOC:mlg] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043591 ! endospore external encapsulating structure + +[Term] +id: GO:0043596 +name: nuclear replication fork +namespace: cellular_component +def: "The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:jl, GOC:mtg_sensu] +is_a: GO:0005657 ! replication fork +intersection_of: GO:0005657 ! replication fork +intersection_of: part_of GO:0005634 ! nucleus +relationship: has_part GO:0071162 ! CMG complex +relationship: part_of GO:0000228 ! nuclear chromosome + +[Term] +id: GO:0043597 +name: cytoplasmic replication fork +namespace: cellular_component +def: "The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:jl, GOC:mtg_sensu] +is_a: GO:0005657 ! replication fork +intersection_of: GO:0005657 ! replication fork +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0000229 ! cytoplasmic chromosome + +[Term] +id: GO:0043598 +name: cytoplasmic DNA replication factor C complex +namespace: cellular_component +def: "A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species." [GOC:mtg_sensu, PMID:14646196, PMID:16172520] +synonym: "cytoplasmic clamp loader" EXACT [] +synonym: "cytoplasmic RFC" EXACT [] +is_a: GO:0005663 ! DNA replication factor C complex +intersection_of: GO:0005663 ! DNA replication factor C complex +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0043600 ! cytoplasmic replisome + +[Term] +id: GO:0043599 +name: nuclear DNA replication factor C complex +namespace: cellular_component +def: "A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species." [GOC:mtg_sensu, PMID:14614842] +synonym: "nuclear RFC" EXACT [] +is_a: GO:0005663 ! DNA replication factor C complex +intersection_of: GO:0005663 ! DNA replication factor C complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0043601 ! nuclear replisome + +[Term] +id: GO:0043600 +name: cytoplasmic replisome +namespace: cellular_component +def: "A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins." [GOC:jl, GOC:mtg_sensu] +synonym: "prokaryotic replisome" EXACT [] +is_a: GO:0030894 ! replisome +intersection_of: GO:0030894 ! replisome +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: has_part GO:0009360 ! DNA polymerase III complex +relationship: has_part GO:0044777 ! single-stranded DNA-binding protein complex +relationship: part_of GO:0043597 ! cytoplasmic replication fork + +[Term] +id: GO:0043601 +name: nuclear replisome +namespace: cellular_component +def: "A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins." [GOC:jl, GOC:mtg_sensu] +is_a: GO:0030894 ! replisome +intersection_of: GO:0030894 ! replisome +intersection_of: part_of GO:0005634 ! nucleus +relationship: has_part GO:0008622 ! epsilon DNA polymerase complex +relationship: part_of GO:0043596 ! nuclear replication fork + +[Term] +id: GO:0043602 +name: nitrate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid." [GOC:jl] +synonym: "nitrate disassimilation" EXACT [] +synonym: "nitrate dissimilation" EXACT [] +is_a: GO:0042126 ! nitrate metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process + +[Term] +id: GO:0043603 +name: cellular amide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators] +subset: goslim_pir +synonym: "amide metabolism" EXACT [] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0043604 +name: amide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process + +[Term] +id: GO:0043605 +name: cellular amide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process + +[Term] +id: GO:0043606 +name: formamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid." [GOC:jl] +synonym: "formamide metabolism" EXACT [] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0043607 +name: formamide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid." [GOC:jl] +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0043606 ! formamide metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0043608 +name: formamide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid." [GOC:jl, http://www.mercksource.com/] +is_a: GO:0043605 ! cellular amide catabolic process +is_a: GO:0043606 ! formamide metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0043609 +name: regulation of carbon utilization +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of carbon utilization." [GOC:jl] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015976 ! carbon utilization +relationship: regulates GO:0015976 ! carbon utilization + +[Term] +id: GO:0043610 +name: regulation of carbohydrate utilization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of carbohydrate utilization." [GOC:jl] +synonym: "regulation of sugar utilization" NARROW [GOC:mcc2] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009758 ! carbohydrate utilization +relationship: regulates GO:0009758 ! carbohydrate utilization + +[Term] +id: GO:0043611 +name: isoprene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isoprene, C5H8." [GOC:jl] +synonym: "2-methyl-1,3-butadiene metabolic process" EXACT [] +synonym: "2-methyl-1,3-butadiene metabolism" EXACT [] +synonym: "hemiterpene metabolic process" EXACT [] +synonym: "hemiterpene metabolism" EXACT [] +synonym: "isoprene metabolism" EXACT [] +is_a: GO:0042214 ! terpene metabolic process +is_a: GO:1900673 ! olefin metabolic process + +[Term] +id: GO:0043612 +name: isoprene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoprene, C5H8." [GOC:jl] +synonym: "2-methyl-1,3-butadiene biosynthesis" EXACT [] +synonym: "2-methyl-1,3-butadiene biosynthetic process" EXACT [] +synonym: "hemiterpene biosynthesis" EXACT [] +synonym: "hemiterpene biosynthetic process" EXACT [] +is_a: GO:0043611 ! isoprene metabolic process +is_a: GO:0046246 ! terpene biosynthetic process +is_a: GO:1900674 ! olefin biosynthetic process + +[Term] +id: GO:0043613 +name: isoprene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8." [GOC:jl] +synonym: "2-methyl-1,3-butadiene catabolic process" EXACT [] +synonym: "2-methyl-1,3-butadiene catabolism" EXACT [] +synonym: "hemiterpene catabolic process" EXACT [] +synonym: "hemiterpene catabolism" EXACT [] +is_a: GO:0043611 ! isoprene metabolic process +is_a: GO:0046247 ! terpene catabolic process + +[Term] +id: GO:0043614 +name: multi-eIF complex +namespace: cellular_component +def: "A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5." [GOC:krc] +synonym: "multifactor translation initiation factor (eIF) complex" EXACT [] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0043615 +name: astrocyte cell migration +namespace: biological_process +def: "The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord." [CL:0000127, GOC:go_curators] +synonym: "astrocyte migration" EXACT [] +synonym: "astrocytic glial cell migration" EXACT [] +is_a: GO:0008347 ! glial cell migration + +[Term] +id: GO:0043616 +name: keratinocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin." [CL:0000311] +is_a: GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0043617 +name: cellular response to sucrose starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose." [GOC:jl] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0043618 +name: regulation of transcription from RNA polymerase II promoter in response to stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0043620 ! regulation of DNA-templated transcription in response to stress + +[Term] +id: GO:0043619 +name: regulation of transcription from RNA polymerase II promoter in response to oxidative stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl] +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +relationship: part_of GO:0034599 ! cellular response to oxidative stress + +[Term] +id: GO:0043620 +name: regulation of DNA-templated transcription in response to stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl, GOC:txnOH] +synonym: "regulation of DNA-dependent transcription in response to stress" EXACT [GOC:txnOH] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0043621 +name: protein self-association +namespace: molecular_function +def: "Interacting selectively and non-covalently with a domain within the same polypeptide." [GOC:jl] +subset: goslim_chembl +synonym: "intramolecular protein binding" EXACT [] +synonym: "protein self association" EXACT [] +synonym: "protein self binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0043622 +name: cortical microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] +synonym: "cortical microtubule cytoskeleton organization" EXACT [] +synonym: "cortical microtubule organisation" EXACT [] +synonym: "cortical microtubule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0030865 ! cortical cytoskeleton organization +is_a: GO:0031122 ! cytoplasmic microtubule organization + +[Term] +id: GO:0043624 +name: cellular protein complex disassembly +namespace: biological_process +def: "The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups." [GOC:jl] +is_a: GO:0032984 ! protein-containing complex disassembly + +[Term] +id: GO:0043625 +name: delta DNA polymerase complex +namespace: cellular_component +alt_id: GO:0005659 +def: "A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair." [GOC:jl, ISBN:0198547684, PMID:11205330, PMID:12403614] +synonym: "delta-DNA polymerase complex" EXACT [] +is_a: GO:0042575 ! DNA polymerase complex +relationship: part_of GO:0043601 ! nuclear replisome + +[Term] +id: GO:0043626 +name: PCNA complex +namespace: cellular_component +def: "A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation." [GOC:jl, PMID:12829735] +synonym: "PCNA homotrimer" EXACT [] +synonym: "proliferating cell nuclear antigen complex" EXACT [] +synonym: "sliding clamp" BROAD [] +is_a: GO:0044796 ! DNA polymerase processivity factor complex + +[Term] +id: GO:0043627 +name: response to estrogen +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics." [GOC:jl, ISBN:0198506732] +synonym: "response to estrogen stimulus" EXACT [GOC:dos] +synonym: "response to oestrogen stimulus" EXACT [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0043628 +name: ncRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a non-coding RNA molecule." [GOC:jl] +synonym: "ncRNA 3' end processing" EXACT [] +is_a: GO:0031123 ! RNA 3'-end processing +is_a: GO:0034470 ! ncRNA processing + +[Term] +id: GO:0043629 +name: ncRNA polyadenylation +namespace: biological_process +def: "The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation." [GOC:dgf, GOC:krc, GOC:rn, PMID:15828860, PMID:15935758, PMID:16374505, PMID:16431988, PMID:18951092] +synonym: "non-coding RNA polyadenylation" EXACT [] +is_a: GO:0034660 ! ncRNA metabolic process +is_a: GO:0043631 ! RNA polyadenylation + +[Term] +id: GO:0043630 +name: ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process +namespace: biological_process +def: "The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism." [GOC:dph, GOC:jl, GOC:tb] +synonym: "ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "ncRNA polyadenylation involved in poly(A)-dependent ncRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0043629 ! ncRNA polyadenylation +relationship: part_of GO:0043634 ! polyadenylation-dependent ncRNA catabolic process + +[Term] +id: GO:0043631 +name: RNA polyadenylation +namespace: biological_process +def: "The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule." [GOC:jl] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0043632 +name: modification-dependent macromolecule catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule." [GOC:jl] +is_a: GO:0044265 ! cellular macromolecule catabolic process + +[Term] +id: GO:0043633 +name: polyadenylation-dependent RNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA." [GOC:dgf, GOC:jl, GOC:krc] +synonym: "polyadenylation-dependent RNA catabolic process" RELATED [GOC:vw] +is_a: GO:0006401 ! RNA catabolic process +is_a: GO:0043632 ! modification-dependent macromolecule catabolic process + +[Term] +id: GO:0043634 +name: polyadenylation-dependent ncRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA." [GOC:dgf, GOC:jl, GOC:krc] +synonym: "poly(A)-dependent ncRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0034661 ! ncRNA catabolic process +is_a: GO:0043633 ! polyadenylation-dependent RNA catabolic process +relationship: has_part GO:0043629 ! ncRNA polyadenylation + +[Term] +id: GO:0043635 +name: methylnaphthalene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar." [GOC:jl, PMID:16535687] +synonym: "1-methylnaphthalene catabolic process" NARROW [] +synonym: "1-methylnaphthalene catabolism" NARROW [] +synonym: "1-MN catabolic process" RELATED [] +synonym: "1-MN catabolism" RELATED [] +synonym: "2-methylnaphthalene catabolic process" NARROW [] +synonym: "2-methylnaphthalene catabolism" NARROW [] +synonym: "2-MN catabolic process" RELATED [] +synonym: "2-MN catabolism" RELATED [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0090420 ! naphthalene-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0043636 +name: bisphenol A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins." [GOC:jl, Wikipedia:Bisphenol_A] +synonym: "bisphenol-A catabolic process" EXACT [] +synonym: "bisphenol-A catabolism" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0043637 +name: puromycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger." [GOC:jl, PMID:8226694, Wikipedia:Puromycin] +synonym: "puromycin metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0043638 +name: puromycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger." [GOC:jl, Wikipedia:Puromycin] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0043637 ! puromycin metabolic process +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process + +[Term] +id: GO:0043639 +name: benzoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid." [GOC:jl] +synonym: "benzoate breakdown" EXACT [] +synonym: "benzoate catabolism" EXACT [] +synonym: "benzoate degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018874 ! benzoate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0043640 +name: benzoate catabolic process via hydroxylation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol." [GOC:jl, MetaCyc:PWY-2503] +synonym: "benzoate breakdown via hydroxylation" EXACT [] +synonym: "benzoate degradation via hydroxylation" EXACT [] +xref: MetaCyc:PWY-2503 +is_a: GO:0043639 ! benzoate catabolic process + +[Term] +id: GO:0043641 +name: novobiocin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase." [GOC:jl] +synonym: "novobiocin metabolism" EXACT [] +xref: Wikipedia:Novobiocin +is_a: GO:0009804 ! coumarin metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0043642 +name: novobiocin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase." [GOC:jl] +xref: Wikipedia:Novobiocin +is_a: GO:0009805 ! coumarin biosynthetic process +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0043641 ! novobiocin metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0043643 +name: tetracycline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [GOC:jl, Wikipedia:Tetracycline] +synonym: "tetracyclin metabolic process" EXACT [] +synonym: "tetracyclin metabolism" EXACT [] +synonym: "tetracycline metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process + +[Term] +id: GO:0043644 +name: tetracycline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [GOC:jl, Wikipedia:Tetracycline] +synonym: "tetracyclin biosynthesis" EXACT [] +synonym: "tetracyclin biosynthetic process" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0043643 ! tetracycline metabolic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process + +[Term] +id: GO:0043645 +name: cephalosporin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria." [GOC:jl, Wikipedia:Cephalosporin] +synonym: "cephalosporin metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process + +[Term] +id: GO:0043646 +name: cephalosporin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria." [GOC:jl, Wikipedia:Cephalosporin] +is_a: GO:0030654 ! beta-lactam antibiotic biosynthetic process +is_a: GO:0043645 ! cephalosporin metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0043647 +name: inositol phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:jl] +synonym: "inositol phosphate metabolism" EXACT [] +synonym: "myo-inositol phosphate metabolic process" NARROW [] +synonym: "myo-inositol phosphate metabolism" NARROW [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0019751 ! polyol metabolic process + +[Term] +id: GO:0043648 +name: dicarboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] +synonym: "dicarboxylate metabolic process" EXACT [] +synonym: "dicarboxylate metabolism" EXACT [] +synonym: "dicarboxylic acid metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0043649 +name: dicarboxylic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] +synonym: "dicarboxylate catabolic process" EXACT [] +synonym: "dicarboxylate catabolism" EXACT [] +synonym: "dicarboxylic acid breakdown" EXACT [] +synonym: "dicarboxylic acid catabolism" EXACT [] +synonym: "dicarboxylic acid degradation" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0043650 +name: dicarboxylic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] +synonym: "dicarboxylate biosynthesis" EXACT [] +synonym: "dicarboxylate biosynthetic process" EXACT [] +synonym: "dicarboxylic acid anabolism" EXACT [] +synonym: "dicarboxylic acid biosynthesis" EXACT [] +synonym: "dicarboxylic acid formation" EXACT [] +synonym: "dicarboxylic acid synthesis" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0043651 +name: linoleic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2." [Wikipedia:Linoleic_Acid] +synonym: "linoleic acid metabolism" EXACT [] +xref: Wikipedia:Linoleic_acid +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process + +[Term] +id: GO:0043652 +name: engulfment of apoptotic cell +namespace: biological_process +def: "The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte." [GOC:rk, PMID:15536015] +comment: This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'. +synonym: "engulfment of apoptotic cell corpse" EXACT [] +synonym: "engulfment of cell corpse" EXACT [] +is_a: GO:0006911 ! phagocytosis, engulfment +relationship: part_of GO:0043277 ! apoptotic cell clearance + +[Term] +id: GO:0043653 +name: mitochondrial fragmentation involved in apoptotic process +namespace: biological_process +def: "The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form." [GOC:mtg_apoptosis, GOC:rk, PMID:12867994] +comment: Although most of the processes described under 'apoptotic mitochondrial changes' take place during the signaling phase of apoptosis, 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed there. It is still controversial whether this process is involved in the signaling phase of apoptosis or not, so it was placed under the more generic 'apoptotic mitochondrial changes' parent rather than linked to the signaling or the execution phase until further research clarifies the matter. +synonym: "mitochondrial fission during apoptosis" RELATED [GOC:dph, GOC:tb] +synonym: "mitochondrial fragmentation involved in apoptosis" NARROW [] +is_a: GO:0008637 ! apoptotic mitochondrial changes + +[Term] +id: GO:0043654 +name: recognition of apoptotic cell +namespace: biological_process +def: "The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis." [GOC:rk, PMID:15536015] +synonym: "detection of apoptotic cell" EXACT [] +synonym: "detection of apoptotic cell corpse" EXACT [] +synonym: "detection of cell corpse" EXACT [] +synonym: "recognition of apoptotic cell corpse" EXACT [] +synonym: "recognition of cell corpse" EXACT [] +is_a: GO:0006910 ! phagocytosis, recognition +relationship: part_of GO:0043277 ! apoptotic cell clearance + +[Term] +id: GO:0043655 +name: host extracellular space +namespace: cellular_component +def: "The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream." [GOC:cc] +synonym: "extracellular space of host" EXACT [] +synonym: "host extracellular space" EXACT [] +is_a: GO:0018995 ! host cellular component + +[Term] +id: GO:0043656 +name: host intracellular region +namespace: cellular_component +def: "That space within the plasma membrane of a host cell." [GOC:cc] +synonym: "host intracellular" EXACT [] +synonym: "intracellular region of host" EXACT [] +is_a: GO:0033643 ! host cell part + +[Term] +id: GO:0043657 +name: host cell +namespace: cellular_component +def: "A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope." [GOC:jl] +is_a: GO:0018995 ! host cellular component + +[Term] +id: GO:0043658 +name: host symbiosome +namespace: cellular_component +def: "A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell." [GOC:cc] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part + +[Term] +id: GO:0043659 +name: symbiosome +namespace: cellular_component +def: "A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane)." [GOC:cc] +is_a: GO:0030139 ! endocytic vesicle + +[Term] +id: GO:0043660 +name: bacteroid-containing symbiosome +namespace: cellular_component +def: "A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants." [GOC:cc] +is_a: GO:0043659 ! symbiosome + +[Term] +id: GO:0043661 +name: peribacteroid membrane +namespace: cellular_component +def: "A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells)." [GOC:cc] +is_a: GO:0030666 ! endocytic vesicle membrane +relationship: part_of GO:0043660 ! bacteroid-containing symbiosome + +[Term] +id: GO:0043662 +name: peribacteroid fluid +namespace: cellular_component +def: "The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome." [GOC:cc] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043660 ! bacteroid-containing symbiosome + +[Term] +id: GO:0043663 +name: host bacteroid-containing symbiosome +namespace: cellular_component +def: "A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell." [GOC:cc] +is_a: GO:0043658 ! host symbiosome + +[Term] +id: GO:0043664 +name: host peribacteroid membrane +namespace: cellular_component +def: "A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells)." [GOC:cc] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0043663 ! host bacteroid-containing symbiosome + +[Term] +id: GO:0043665 +name: host peribacteroid fluid +namespace: cellular_component +def: "The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell." [GOC:cc] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0043663 ! host bacteroid-containing symbiosome + +[Term] +id: GO:0043666 +name: regulation of phosphoprotein phosphatase activity +namespace: biological_process +alt_id: GO:0032512 +alt_id: GO:0034047 +def: "Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein." [GOC:jp, PMID:11724821] +synonym: "regulation of calcineurin activity" NARROW [] +synonym: "regulation of protein phosphatase 3 activity" RELATED [GOC:dph, GOC:rl] +synonym: "regulation of protein phosphatase type 2 activity" RELATED [GOC:dph, GOC:rl] +synonym: "regulation of protein phosphatase type 2A activity" NARROW [] +synonym: "regulation of protein phosphatase type 2B activity" NARROW [] +is_a: GO:0010921 ! regulation of phosphatase activity +is_a: GO:0035304 ! regulation of protein dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004721 ! phosphoprotein phosphatase activity +relationship: regulates GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0043667 +name: pollen wall +namespace: cellular_component +def: "The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine." [GOC:fz, PMID:15131249] +synonym: "microspore wall" EXACT [] +is_a: GO:0030312 ! external encapsulating structure + +[Term] +id: GO:0043668 +name: exine +namespace: cellular_component +def: "The outer layer of the pollen grain wall which is composed primarily of sporopollenin." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that the exine is highly resistant to strong acids and bases. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043667 ! pollen wall + +[Term] +id: GO:0043669 +name: ectexine +namespace: cellular_component +def: "The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that ectexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'endexine ; GO:0043671'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043668 ! exine + +[Term] +id: GO:0043670 +name: foot layer +namespace: cellular_component +def: "The inner layer of the ectexine." [http://www.mobot.org/MOBOT/research/APweb/] +synonym: "nexine 1" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043669 ! ectexine + +[Term] +id: GO:0043671 +name: endexine +namespace: cellular_component +def: "The inner part of the exine, which stains." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that endexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'ectexine ; GO:0043669'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043668 ! exine + +[Term] +id: GO:0043672 +name: nexine +namespace: cellular_component +def: "The inner, non-sculptured part of the exine which lies below the sexine." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that nexine is distinguished on purely morphological criteria; compare with 'endexine ; GO:0043671'. See also 'sexine ; GO:0043673'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043668 ! exine + +[Term] +id: GO:0043673 +name: sexine +namespace: cellular_component +def: "The outer, sculptured layer of the exine, which lies above the nexine." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that the sexine sometimes consists of 5 layers, but of those, 3 layers are the most common (sexine 1 = columellae; sexine 2 = tectum; sexine 3 = sculpture elements). Sexine is distinguished on purely morphological criteria; compare with 'ectexine ; GO:0043669'. See also 'nexine ; GO:0043672'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043668 ! exine + +[Term] +id: GO:0043674 +name: columella +namespace: cellular_component +def: "A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella)." [http://www.mobot.org/MOBOT/research/APweb/] +synonym: "sexine 1" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043673 ! sexine + +[Term] +id: GO:0043675 +name: sculpture element +namespace: cellular_component +def: "The third layer of the sexine." [http://www.mobot.org/MOBOT/research/APweb/] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043673 ! sexine + +[Term] +id: GO:0043676 +name: tectum +namespace: cellular_component +def: "The layer of sexine which forms a roof over the columella, granules or other infratectal elements." [http://www.mobot.org/MOBOT/research/APweb/] +synonym: "sexine 2" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043673 ! sexine + +[Term] +id: GO:0043677 +name: obsolete germination pore +namespace: cellular_component +def: "OBSOLETE. A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location." [Wikipedia:Germ_pore] +comment: This term was made obsolete because it was poorly named and poorly defined. +synonym: "germ pore" EXACT [] +xref: Wikipedia:Germ_pore +is_obsolete: true + +[Term] +id: GO:0043678 +name: intine +namespace: cellular_component +def: "The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm." [http://www.mobot.org/MOBOT/research/APweb/] +comment: Note that the intine is not acetolysis resistant and is therefore absent in conventionally prepared palynological material. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043667 ! pollen wall + +[Term] +id: GO:0043679 +name: axon terminus +namespace: cellular_component +def: "Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it." [GOC:dph, GOC:jl] +synonym: "axon terminal" EXACT [NIF_Subcellular:sao2007137787] +synonym: "axon terminal specialization" RELATED [] +synonym: "nerve ending" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090512 +is_a: GO:0044306 ! neuron projection terminus +is_a: GO:0098793 ! presynapse +relationship: part_of GO:0150034 ! distal axon + +[Term] +id: GO:0043680 +name: filiform apparatus +namespace: cellular_component +def: "A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells." [ISBN:0471245208] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005618 ! cell wall + +[Term] +id: GO:0043682 +name: copper transmembrane transporter activity, phosphorylative mechanism +namespace: molecular_function +alt_id: GO:0004008 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out)." [EC:7.2.2.9] +synonym: "copper exporting ATPase activity" EXACT [] +synonym: "copper-exporting ATPase activity" RELATED [] +synonym: "copper-translocating P-type ATPase activity" RELATED [] +synonym: "copper-transporting ATPase activity" EXACT [] +synonym: "Cu(2+)-exporting ATPase activity" EXACT [EC:7.2.2.9] +synonym: "Cu2+-exporting ATPase activity" EXACT [EC:7.2.2.9] +xref: EC:7.2.2.9 +xref: MetaCyc:3.6.3.4-RXN +xref: Reactome:R-HSA-3697838 "ATP7A transfers Cu from ATOX1 to SOD3" +xref: Reactome:R-HSA-6803545 "ATP7A transports cytosolic Cu2+ to phagosomal lumen" +xref: Reactome:R-HSA-936802 "ATP7A transports cytosolic Cu2+ to extracellular region" +xref: Reactome:R-HSA-936895 "ATP7B transports cytosolic Cu2+ to Golgi lumen" +xref: RHEA:10376 +is_a: GO:0005375 ! copper ion transmembrane transporter activity +is_a: GO:0015662 ! ion transmembrane transporter activity, phosphorylative mechanism +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity +is_a: GO:0072509 ! divalent inorganic cation transmembrane transporter activity + +[Term] +id: GO:0043683 +name: type IV pilus biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a type IV pilus. A type IV pilus is composed of a pilus fiber and approximately ten proteins at its base; type IV pili play a role in cell motility, adherence to substrates, and aggregation." [GOC:jl, GOC:ml] +synonym: "TFP biogenesis" EXACT [] +synonym: "type 4 pilus biogenesis" EXACT [] +synonym: "type IV fimbria assembly" EXACT [] +synonym: "type IV fimbria biogenesis" EXACT [] +synonym: "type IV fimbriae assembly" EXACT [] +synonym: "type IV fimbriae biogenesis" EXACT [] +synonym: "type IV fimbrial assembly" EXACT [] +synonym: "type IV fimbrial biogenesis" EXACT [] +synonym: "type IV fimbrium assembly" EXACT [] +synonym: "type IV fimbrium biogenesis" EXACT [] +synonym: "type IV pilus biosynthesis" EXACT [] +is_a: GO:0009297 ! pilus assembly +is_a: GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0043684 +name: type IV secretion system complex +namespace: cellular_component +def: "A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s)." [GOC:ml] +synonym: "T4SS complex" EXACT [] +synonym: "type IV protein secretion system complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0043685 +name: conversion of glutamyl-tRNA to glutaminyl-tRNA +namespace: biological_process +def: "The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA." [GOC:jsg, PMID:3340166, PMID:9342308] +comment: Note that this process has been observed in some archaeal and bacterial species. +is_a: GO:0019988 ! charged-tRNA amino acid modification + +[Term] +id: GO:0043686 +name: co-translational protein modification +namespace: biological_process +def: "The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome." [GOC:jsg] +comment: This term should only be used to annotate a protein modification process that occurs after the start of translation but while the protein is still on the ribosome. +synonym: "co-translational amino acid modification" EXACT [] +synonym: "co-translational modification" EXACT [] +synonym: "cotranslational amino acid modification" EXACT [] +synonym: "cotranslational modification" EXACT [] +synonym: "cotranslational protein modification" EXACT [] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0043687 +name: post-translational protein modification +namespace: biological_process +def: "The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome." [GOC:jsg] +comment: This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term. +synonym: "post-translational amino acid modification" EXACT [] +synonym: "post-translational modification" EXACT [] +synonym: "posttranslational amino acid modification" EXACT [] +synonym: "posttranslational modification" EXACT [] +synonym: "posttranslational protein modification" EXACT [] +synonym: "PTM" EXACT [] +xref: Wikipedia:Posttranslational_modification +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0043688 +name: conversion of aspartyl-tRNA to asparaginyl-tRNA +namespace: biological_process +def: "The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA." [GOC:jsg, PMID:9789001] +comment: Note that this process has been observed in some archaeal and bacterial species. +is_a: GO:0019988 ! charged-tRNA amino acid modification + +[Term] +id: GO:0043691 +name: reverse cholesterol transport +namespace: biological_process +def: "The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism." [GOC:ecd, PMID:7751809] +is_a: GO:0030301 ! cholesterol transport + +[Term] +id: GO:0043692 +name: monoterpene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure." [Wikipedia:Monoterpene] +synonym: "monoterpene metabolism" EXACT [] +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0043693 +name: monoterpene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure." [Wikipedia:Monoterpene] +synonym: "monoterpene biosynthesis" EXACT [] +is_a: GO:0043692 ! monoterpene metabolic process +is_a: GO:0046246 ! terpene biosynthetic process + +[Term] +id: GO:0043694 +name: monoterpene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure." [PMID:25076942] +synonym: "monoterpene catabolism" EXACT [] +is_a: GO:0043692 ! monoterpene metabolic process +is_a: GO:0046247 ! terpene catabolic process + +[Term] +id: GO:0043695 +name: detection of pheromone +namespace: biological_process +def: "The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal." [GOC:mah] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0019236 ! response to pheromone + +[Term] +id: GO:0043696 +name: dedifferentiation +namespace: biological_process +def: "The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors." [GOC:dph, GOC:pg] +xref: Wikipedia:Cellular_differentiation#Dedifferentiation +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0043697 +name: cell dedifferentiation +namespace: biological_process +def: "The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors." [GOC:dph, GOC:pg] +comment: Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer. +is_a: GO:0043696 ! dedifferentiation +is_a: GO:0048869 ! cellular developmental process + +[Term] +id: GO:0043698 +name: iridosome +namespace: cellular_component +def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance." [GOC:mh] +synonym: "reflecting platelet" EXACT [] +is_a: GO:0048770 ! pigment granule +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0043699 +name: leucosome +namespace: cellular_component +def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast." [GOC:mh] +synonym: "refractosome" EXACT [] +is_a: GO:0048770 ! pigment granule + +[Term] +id: GO:0043700 +name: pterinosome +namespace: cellular_component +def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance." [GOC:mh] +is_a: GO:0048770 ! pigment granule +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0043701 +name: cyanosome +namespace: cellular_component +def: "A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance." [GOC:mh] +is_a: GO:0048770 ! pigment granule +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0043702 +name: carotenoid vesicle +namespace: cellular_component +def: "A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance." [GOC:mh] +is_a: GO:0031410 ! cytoplasmic vesicle +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0043703 +name: photoreceptor cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:mtg_sensu] +is_a: GO:0048664 ! neuron fate determination +relationship: part_of GO:0046552 ! photoreceptor cell fate commitment + +[Term] +id: GO:0043704 +name: photoreceptor cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GOC:mtg_sensu] +is_a: GO:0048665 ! neuron fate specification +relationship: part_of GO:0046552 ! photoreceptor cell fate commitment + +[Term] +id: GO:0043705 +name: cyanophycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups." [GOC:jl] +synonym: "cyanophycin metabolism" EXACT [] +synonym: "multi-L-arginyl-poly(L-aspartic acid) metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0043707 +name: cell adhesion involved in single-species biofilm formation in or on host organism +namespace: biological_process +def: "The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species." [GOC:jl] +synonym: "cell adhesion during single-species biofilm formation in or on host organism" RELATED [GOC:dph] +is_a: GO:0043709 ! cell adhesion involved in single-species biofilm formation +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0044407 ! single-species biofilm formation in or on host organism +relationship: part_of GO:0044407 ! single-species biofilm formation in or on host organism + +[Term] +id: GO:0043708 +name: cell adhesion involved in biofilm formation +namespace: biological_process +def: "The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm." [GOC:dph, GOC:jl, GOC:tb] +synonym: "cell adhesion during biofilm formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0031589 ! cell-substrate adhesion +intersection_of: GO:0031589 ! cell-substrate adhesion +intersection_of: part_of GO:0042710 ! biofilm formation +relationship: part_of GO:0090605 ! submerged biofilm formation + +[Term] +id: GO:0043709 +name: cell adhesion involved in single-species biofilm formation +namespace: biological_process +def: "The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species." [GOC:dph, GOC:jl, GOC:tb] +synonym: "cell adhesion during single-species biofilm formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043708 ! cell adhesion involved in biofilm formation +intersection_of: GO:0031589 ! cell-substrate adhesion +intersection_of: part_of GO:0044010 ! single-species biofilm formation +relationship: part_of GO:0090609 ! single-species submerged biofilm formation + +[Term] +id: GO:0043710 +name: cell adhesion involved in multi-species biofilm formation +namespace: biological_process +def: "The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species." [GOC:dph, GOC:jl, GOC:tb] +synonym: "cell adhesion during multi-species biofilm formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043708 ! cell adhesion involved in biofilm formation +intersection_of: GO:0031589 ! cell-substrate adhesion +intersection_of: part_of GO:0044399 ! multi-species biofilm formation +relationship: part_of GO:0090608 ! multi-species submerged biofilm formation + +[Term] +id: GO:0043711 +name: pilus organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies." [GOC:jl] +synonym: "pilus organisation" EXACT [GOC:mah] +synonym: "pilus organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0030030 ! cell projection organization + +[Term] +id: GO:0043712 +name: 2-hydroxyisocaproate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate." [PMID:16957230] +synonym: "(R)-2-hydroxyisocaproate CoA transferase activity" EXACT [] +synonym: "(R)-2-hydroxyisocaproate CoA-transferase activity" EXACT [] +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0043713 +name: (R)-2-hydroxyisocaproate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+." [GOC:jl, PMID:16957230] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043714 +name: (R)-citramalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA." [GOC:jl, PMID:9864346] +synonym: "citramalate synthase" BROAD [] +xref: EC:2.3.1.182 +xref: MetaCyc:RXN-7743 +xref: RHEA:19045 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0043715 +name: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P." [MetaCyc:R82-RXN] +comment: This function is part of the process of methionine salvage. +synonym: "DK-MTP-1-P enolase activity" EXACT [] +synonym: "E-1" RELATED [] +synonym: "MasA" RELATED [] +synonym: "mtnW" RELATED [] +xref: EC:5.3.2.5 +xref: MetaCyc:R82-RXN +xref: RHEA:18769 +is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups + +[Term] +id: GO:0043716 +name: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene." [EC:3.1.3.77, MetaCyc:R83-RXN] +synonym: "2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity" EXACT [MetaCyc:R83-RXN] +synonym: "HK-MTPenyl-1-P phosphatase activity" EXACT [] +xref: KEGG_REACTION:R07394 +xref: MetaCyc:R83-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0043717 +name: 2-hydroxyglutaryl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA." [MetaCyc:RXN-1083] +synonym: "(R)-2-hydroxyglutaryl-CoA dehydratase activity" EXACT [] +xref: MetaCyc:RXN-1083 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043718 +name: 2-hydroxymethylglutarate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH." [EC:1.1.1.291, RHEA:15505] +synonym: "(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.291] +synonym: "HgD" EXACT [] +xref: EC:1.1.1.291 +xref: KEGG_REACTION:R07985 +xref: MetaCyc:1.1.1.291-RXN +xref: RHEA:15505 +xref: Wikipedia:2-hydroxymethylglutarate_dehydrogenase +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043719 +name: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O." [GOC:jl, MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN] +xref: EC:1.14.13 +xref: MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0043720 +name: 3-keto-5-aminohexanoate cleavage activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate." [MetaCyc:R125-RXN, PMID:13064] +synonym: "3-keto-5-aminohexanoate cleavage enzyme" EXACT [] +xref: MetaCyc:R125-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043721 +name: 4-hydroxybutanoyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O." [EC:4.2.1.120] +synonym: "4-hydroxybutanoyl-CoA hydro-lyase" EXACT [] +synonym: "4-hydroxybutyryl-CoA dehydratase activity" EXACT [] +synonym: "gamma-hydroxybutanoyl-CoA dehydratase activity" EXACT [] +synonym: "gamma-hydroxybutyryl-CoA dehydratase activity" EXACT [] +xref: EC:4.2.1.120 +xref: KEGG_REACTION:R05337 +xref: MetaCyc:RXN-8890 +xref: RHEA:26530 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043722 +name: 4-hydroxyphenylacetate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2)." [EC:4.1.1.83, RHEA:22732] +synonym: "4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)" EXACT [EC:4.1.1.83] +synonym: "4-Hpd activity" EXACT [EC:4.1.1.83] +synonym: "4-hydroxyphenylacetate carboxy-lyase activity" EXACT [EC:4.1.1.83] +synonym: "p-Hpd activity" EXACT [EC:4.1.1.83] +synonym: "p-hydroxyphenylacetate decarboxylase activity" EXACT [EC:4.1.1.83] +xref: EC:4.1.1.83 +xref: KEGG_REACTION:R07312 +xref: MetaCyc:4.1.1.83-RXN +xref: RHEA:22732 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0043723 +name: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity +namespace: molecular_function +alt_id: GO:0017173 +def: "Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia." [MetaCyc:RXN-10058, PMID:11889103] +synonym: "2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity" EXACT [MetaCyc:YOL066C-MONOMER] +synonym: "DRAP deaminase activity" EXACT [] +xref: MetaCyc:RXN-10058 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0043724 +name: 2-keto-3-deoxygalactonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate." [PMID:12824170] +synonym: "KDGal aldolase activity" EXACT [] +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043726 +name: 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity +namespace: molecular_function +alt_id: GO:0019173 +def: "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate." [GOC:jl] +synonym: "pyrimidine phosphatase activity" EXACT [GOC:mah] +xref: EC:3.1.3 +xref: MetaCyc:RIBOPHOSPHAT-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0043727 +name: 5-amino-4-imidazole carboxylate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate." [GOC:jl] +xref: EC:4.1.1.21 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0043728 +name: 2-keto-4-methylthiobutyrate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine." [GOC:jl] +xref: EC:4.1.1 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043729 +name: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate." [GOC:jl] +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0043730 +name: 5-ureido-4-imidazole carboxylate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2." [GOC:jl] +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0043731 +name: 6-hydroxynicotinate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD." [GOC:jl, PMID:10091591] +xref: EC:1.14.13.114 +xref: MetaCyc:RXN-7573 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0043732 +name: 6-hydroxynicotinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2)." [EC:1.17.3.3, RHEA:22808] +synonym: "6-hydroxynicotinate hydroxylase activity" EXACT [EC:1.17.3.3] +synonym: "6-hydroxynicotinate:O2 oxidoreductase activity" EXACT [EC:1.17.3.3] +synonym: "6-hydroxynicotinic acid dehydrogenase activity" EXACT [EC:1.17.3.3] +synonym: "6-hydroxynicotinic acid hydroxylase activity" EXACT [EC:1.17.3.3] +xref: EC:1.17.3.3 +xref: KEGG_REACTION:R07221 +xref: MetaCyc:RXN-7585 +xref: RHEA:22808 +is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor + +[Term] +id: GO:0043733 +name: DNA-3-methylbase glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site." [PMID:10777493, PMID:14517230] +synonym: "DNA-3-methyladenine glycosylase III" RELATED [] +synonym: "Mag III" NARROW [] +synonym: "MagIII" NARROW [] +xref: EC:3.2.2 +is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity + +[Term] +id: GO:0043734 +name: DNA-N1-methyladenine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde." [PMID:19786499] +synonym: "AlkB" NARROW [] +synonym: "alpha-ketoglutarate-dependent dioxygenase" NARROW [] +xref: Reactome:R-HSA-112118 "Oxidative demethylation of 1-meA damaged DNA by ALKBH2" +xref: Reactome:R-HSA-112123 "Oxidative demethylation of 1-meA damaged DNA By ALKBH3" +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0043736 +name: obsolete DNA-3-methyladenine glycosylase IV activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site." [PMID:10375529] +comment: This term was made obsolete because it represents an enzyme with four different activities. +synonym: "DNA-3-methyladenine glycosylase IV activity" EXACT [] +synonym: "Mpg II" NARROW [] +synonym: "MpgII" NARROW [] +is_obsolete: true +consider: GO:0008725 +consider: GO:0043916 +consider: GO:0052821 +consider: GO:0052822 + +[Term] +id: GO:0043737 +name: deoxyribonuclease V activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate." [EC:3.1.21.7] +synonym: "DNase V activity" EXACT [EC:3.1.21.7] +synonym: "endodeoxyribonuclease V" EXACT [] +synonym: "endonuclease V activity" BROAD [EC:3.1.21.7] +synonym: "Escherichia coli endodeoxyribonuclease V activity" NARROW [EC:3.1.21.7] +xref: EC:3.1.21.7 +xref: MetaCyc:3.1.21.7-RXN +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0043738 +name: reduced coenzyme F420 dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420." [MetaCyc:RXN-8106] +synonym: "1,5-dihydrocoenzyme F420 dehydrogenase activity" EXACT [CHEBI:15823] +synonym: "F420H2 dehydrogenase activity" EXACT [] +xref: EC:1.5.98.3 +xref: MetaCyc:RXN-8106 +xref: RHEA:54752 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043739 +name: G/U mismatch-specific uracil-DNA glycosylase activity +namespace: molecular_function +def: "Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site." [PMID:24739389] +synonym: "GU mismatch-specific uracil-DNA glycosylase activity" EXACT [] +synonym: "MUG" EXACT [] +synonym: "uracil mismatch repair protein" BROAD [] +is_a: GO:0004844 ! uracil DNA N-glycosylase activity +is_a: GO:0008263 ! pyrimidine-specific mismatch base pair DNA N-glycosylase activity + +[Term] +id: GO:0043740 +name: GTP cyclohydrolase IIa activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate." [EC:3.5.4.29, RHEA:22468] +synonym: "GTP 8,9-dihydrolase (phosphate-forming)" EXACT [EC:3.5.4.29] +synonym: "GTP 8,9-hydrolase (phosphate-forming)" EXACT [] +synonym: "GTP cyclohydrolase III activity" NARROW [EC:3.5.4.29] +xref: EC:3.5.4.29 +xref: KEGG_REACTION:R07306 +xref: MetaCyc:RXN-10055 +xref: RHEA:22468 +is_a: GO:0003933 ! GTP cyclohydrolase activity + +[Term] +id: GO:0043741 +name: alpha-aminoadipate acetyltransferase activity +namespace: molecular_function +alt_id: GO:0043869 +def: "Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A." [PMID:10613839, PMID:12925802, PMID:29053735] +synonym: "L-2-aminoadipate N-acetyltransferase activity" RELATED [] +xref: MetaCyc:RXN-5181 +is_a: GO:0008080 ! N-acetyltransferase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18958 xsd:anyURI + +[Term] +id: GO:0043743 +name: LPPG:FO 2-phospho-L-lactate transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP." [PMID:11888293] +xref: EC:2.7.8.28 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043744 +name: N2-acetyl-L-aminoadipate kinase activity +namespace: molecular_function +alt_id: GO:0043868 +def: "Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate." [PMID:25392000, PMID:26966182, RHEA:41944] +synonym: "[LysW]-aminoadipate kinase" RELATED [] +synonym: "acetylaminoadipate kinase activity" EXACT [] +synonym: "N-acetyl-L-aminoadipate 5-phosphotransferase activity" EXACT [] +synonym: "N-acetylaminoadipate kinase activity" EXACT [] +xref: MetaCyc:RXN-5182 +xref: RHEA:41944 +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0043745 +name: N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate." [IMG:01449] +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043746 +name: N2-acetyl-L-lysine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine." [IMG:01450] +synonym: "N-acetyl-lysine aminotransferase activity" EXACT [] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043747 +name: N2-acetyl-L-lysine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine." [IMG:01451] +synonym: "N-acetyl-lysine deacetylase activity" EXACT [] +xref: MetaCyc:RXN-5185 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0043748 +name: O-succinylbenzoate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate." [PMID:8335646] +xref: EC:4.2.1.113 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043749 +name: phenol, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate." [PMID:15547277] +synonym: "ATP:phenol:water phosphotransferase activity" EXACT [] +synonym: "phenol:water dikinase activity" EXACT [] +synonym: "phenylphosphate synthase activity" EXACT [] +xref: EC:2.7.9 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0043750 +name: phosphatidylinositol alpha-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol." [EC:2.4.1.345] +synonym: "GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity" EXACT [] +synonym: "GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity" EXACT [] +synonym: "GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity" EXACT [] +synonym: "GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity" EXACT [] +synonym: "guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity" EXACT [] +synonym: "phosphatidyl-myo-inositol alpha-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.345 +xref: MetaCyc:2.4.1.57-RXN +xref: RHEA:47368 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0043751 +name: polyphosphate:AMP phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP." [PMID:11237733] +synonym: "PAP" EXACT [] +synonym: "PPT" BROAD [] +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0043752 +name: adenosylcobinamide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP)." [EC:2.7.1.156] +synonym: "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase" BROAD [] +synonym: "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase" BROAD [] +synonym: "CobU" RELATED [] +synonym: "RTP:adenosylcobinamide phosphotransferase activity" EXACT [] +xref: EC:2.7.1.156 +xref: MetaCyc:2.7.1.156-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043754 +name: dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine." [EC:2.3.1.168] +synonym: "2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" EXACT [EC:2.3.1.168] +synonym: "2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" EXACT [EC:2.3.1.168] +synonym: "dihydrolipoyl transacylase activity" EXACT [EC:2.3.1.168] +synonym: "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity" EXACT [] +xref: EC:2.3.1.168 +xref: MetaCyc:2.3.1.168-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043755 +name: alpha-ribazole phosphatase activity +namespace: molecular_function +alt_id: GO:0019175 +def: "Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate." [EC:3.1.3.73, RHEA:24456] +synonym: "alpha-ribazole-5'-P phosphatase activity" EXACT [] +synonym: "alpha-ribazole-5'-phosphate phosphohydrolase activity" EXACT [] +synonym: "CobC" RELATED [] +xref: EC:3.1.3.73 +xref: KEGG_REACTION:R04594 +xref: MetaCyc:RIBAZOLEPHOSPHAT-RXN +xref: RHEA:24456 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0043756 +name: adenosylcobinamide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate." [EC:3.5.1.90, RHEA:23504] +synonym: "adenosylcobinamide amidohydrolase activity" EXACT [EC:3.5.1.90] +synonym: "AdoCbi amidohydrolase activity" EXACT [EC:3.5.1.90] +synonym: "AdoCbi hydrolase activity" EXACT [EC:3.5.1.90] +synonym: "CbiZ" RELATED [] +xref: EC:3.5.1.90 +xref: KEGG_REACTION:R05226 +xref: MetaCyc:R346-RXN +xref: RHEA:23504 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0043757 +name: adenosylcobinamide-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide." [EC:6.3.1.10] +synonym: "adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)" EXACT [] +synonym: "AdoCbi-P synthase activity" EXACT [EC:6.3.1.10] +synonym: "CbiB" RELATED [] +xref: EC:6.3.1.10 +xref: MetaCyc:RXN-6261 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0043758 +name: acetate-CoA ligase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA." [EC:6.2.1.13] +synonym: "acetate thiokinase activity" BROAD [EC:6.2.1.13] +synonym: "acetate--CoA ligase (ADP-forming) activity" EXACT [] +synonym: "acetate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.13] +synonym: "acetyl coenzyme A synthetase (adenosine diphosphate-forming)" EXACT [] +synonym: "acetyl-CoA synthetase (ADP-forming) activity" EXACT [EC:6.2.1.13] +xref: EC:6.2.1.13 +xref: MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN +xref: RHEA:15081 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0043759 +name: branched-chain acyl-CoA synthetase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = ADP + orthophosphate + 2-methylbutanoyl-CoA." [IMG:01425] +synonym: "branched chain acyl CoA synthetase (ADP-forming) activity" EXACT [] +synonym: "branched chain acyl-CoA synthetase (ADP-forming) activity" EXACT [] +synonym: "branched-chain acyl CoA synthetase (ADP-forming) activity" EXACT [] +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0043760 +name: acetyldiaminopimelate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate." [PMID:1906065] +synonym: "N-acetyl-diaminopimelate aminotransferase activity" EXACT [] +synonym: "N-acetyl-L,L-diaminopimelate aminotransferase activity" EXACT [] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043761 +name: archaetidylserine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP." [PMID:12562787] +synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity" EXACT [] +synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity" EXACT [] +xref: EC:2.7.8.38 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0043762 +name: aryl-CoA synthetase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + phenylacetate + CoA = ADP + orthophosphate + phenylacetyl-CoA." [IMG:01427] +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0043763 +name: UTP:glucose-1-phosphate uridylyltransferase regulator activity +namespace: molecular_function +def: "Modulates the activity of UTP:glucose-1-phosphate uridylyltransferase." [GOC:jl] +synonym: "glucose-1-phosphate uridylyltransferase regulator activity" EXACT [] +synonym: "UDP-glucose diphosphorylase regulator activity" EXACT [] +synonym: "UDP-glucose pyrophosphorylase regulator activity" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0003983 ! UTP:glucose-1-phosphate uridylyltransferase activity + +[Term] +id: GO:0043765 +name: T/G mismatch-specific endonuclease activity +namespace: molecular_function +def: "Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine." [PMID:17651368] +synonym: "DNA mismatch endonuclease" BROAD [] +synonym: "V.EcoKDcm" RELATED [] +synonym: "very short patch repair protein" RELATED [] +synonym: "Vsr mismatch endonuclease" RELATED [] +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0043766 +name: Sep-tRNA:Cys-tRNA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate." [PMID:15790858, PMID:16380427, PMID:17110438] +synonym: "O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity" EXACT [] +synonym: "Sep-tRNA:Cys-tRNA synthetase activity" EXACT [] +synonym: "SepCysS" RELATED [] +xref: EC:2.5.1.73 +xref: MetaCyc:RXN-10719 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0071952 ! conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA + +[Term] +id: GO:0043767 +name: pyrrolysyl-tRNA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)." [PMID:15314242, RHEA:19277] +synonym: "PylRS" EXACT [] +synonym: "pyrrolysine-tRNA ligase activity" EXACT [] +xref: EC:6.1.1.26 +xref: MetaCyc:6.1.1.26-RXN +xref: RHEA:19277 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0043768 +name: S-ribosylhomocysteine lyase activity +namespace: molecular_function +alt_id: GO:0019138 +def: "Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine." [RHEA:17753] +synonym: "LuxS" RELATED [] +synonym: "ribosylhomocysteinase activity" EXACT [] +synonym: "S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]" RELATED [EC:4.4.1.21] +synonym: "S-ribosylhomocysteinase activity" EXACT [] +xref: EC:4.4.1.21 +xref: KEGG_REACTION:R01291 +xref: MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN +xref: RHEA:17753 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0043769 +name: Tpg-containing telomere binding complex +namespace: cellular_component +def: "A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species." [PMID:15353591] +synonym: "telomere complex" BROAD [] +is_a: GO:0000782 ! telomere cap complex + +[Term] +id: GO:0043770 +name: demethylmenaquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine." [PMID:1444716, PMID:9045837, RHEA:26466] +xref: EC:2.1.1.163 +xref: RHEA:26466 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043771 +name: cytidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + cytidine = ADP + CMP." [PMID:211379] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019206 ! nucleoside kinase activity +relationship: part_of GO:0009224 ! CMP biosynthetic process + +[Term] +id: GO:0043772 +name: acyl-phosphate glycerol-3-phosphate acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate." [PMID:17308305] +synonym: "acyl-phosphate:glycerol-3-phosphate acyltransferase activity" EXACT [] +synonym: "acylphosphate glycerol-3-phosphate acyltransferase activity" EXACT [] +synonym: "acylphosphate:glycerol-3-phosphate acyltransferase activity" EXACT [] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043773 +name: coenzyme F420-0 gamma-glutamyl ligase activity +namespace: molecular_function +def: "Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates." [PMID:17669425] +synonym: "F420-0 gamma-glutamyl ligase activity" EXACT [] +xref: EC:6.3.2.34 +xref: RHEA:30523 +is_a: GO:0016881 ! acid-amino acid ligase activity +relationship: has_part GO:0052618 ! coenzyme F420-0:L-glutamate ligase activity +relationship: has_part GO:0052619 ! coenzyme F420-1:gamma-L-glutamate ligase activity + +[Term] +id: GO:0043774 +name: coenzyme F420-2 alpha-glutamyl ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate." [PMID:12909715] +synonym: "F420-2 alpha-glutamyl ligase activity" EXACT [] +xref: EC:6.3.2.32 +xref: RHEA:42332 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0043776 +name: cobalt-precorrin-6B C5-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7." [MetaCyc:RXN-8766] +synonym: "cobalt-precorrin 6B C5-methyltransferase activity" EXACT [] +synonym: "precorrin-6 methyltransferase activity" EXACT [] +synonym: "precorrin-6Y C5,15-methyltransferase (decarboxylating)" BROAD [] +synonym: "precorrin-6Y methylase" BROAD [] +xref: MetaCyc:RXN-8766 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043777 +name: cobalt-precorrin-7 C15-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2." [MetaCyc:RXN-8767] +synonym: "cobalt-precorrin 7 C15-methyltransferase activity" EXACT [] +synonym: "precorrin-6 methyltransferase" BROAD [] +synonym: "precorrin-6Y C5,15-methyltransferase (decarboxylating)" BROAD [] +synonym: "precorrin-6Y methylase" BROAD [] +xref: MetaCyc:RXN-8767 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043778 +name: cobalt-precorrin-8 methylmutase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate." [MetaCyc:RXN-8768] +synonym: "cobalt-precorrin 8 methylmutase activity" EXACT [] +synonym: "cobalt-precorrin 8X methylmutase activity" EXACT [] +synonym: "cobalt-precorrin-8X methylmutase activity" EXACT [] +xref: EC:5.4.99.60 +xref: MetaCyc:RXN-8768 +xref: RHEA:16209 +is_a: GO:0016867 ! intramolecular transferase activity, transferring acyl groups + +[Term] +id: GO:0043779 +name: cobalt-precorrin-5A acetaldehyde-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde." [MetaCyc:RXN-8763] +synonym: "cobalt-precorrin 5A acetaldehyde-lyase activity" EXACT [] +xref: MetaCyc:RXN-8763 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0043780 +name: cobalt-precorrin-5B C1-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A." [MetaCyc:RXN-8764] +synonym: "cobalt-precorrin 5B C1-methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-8764 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043781 +name: cobalt-factor II C20-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III." [EC:2.1.1.151] +synonym: "CbiL" NARROW [] +synonym: "cobalt-factor II C20 methyltransferase activity" EXACT [] +synonym: "cobalt-precorrin-2 C(20)-methyltransferase activity" EXACT [EC:2.1.1.151] +synonym: "S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity" EXACT [EC:2.1.1.151] +xref: EC:2.1.1.151 +xref: MetaCyc:RXN-8760 +xref: RHEA:17997 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043782 +name: cobalt-precorrin-3 C17-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine." [MetaCyc:RXN-8761] +synonym: "cobalt-precorrin 3 C17-methyltransferase activity" EXACT [] +synonym: "cobalt-precorrin-3 methylase" BROAD [] +synonym: "cobalt-precorrin-3 methyltransferase" BROAD [] +synonym: "cobalt-precorrin-3B C17-methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-8761 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043783 +name: oxidoreductase activity, oxidizing metal ions with flavin as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and flavin acts as an electron acceptor." [EC:1.16.8] +xref: EC:1.16.8 +is_a: GO:0016722 ! oxidoreductase activity, oxidizing metal ions + +[Term] +id: GO:0043784 +name: cob(II)yrinic acid a,c-diamide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2)." [EC:1.16.8.1, RHEA:24300] +synonym: "cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity" EXACT [] +xref: EC:1.16.8.1 +xref: KEGG_REACTION:R05218 +xref: MetaCyc:R343-RXN +xref: RHEA:24300 +is_a: GO:0043783 ! oxidoreductase activity, oxidizing metal ions with flavin as acceptor + +[Term] +id: GO:0043785 +name: cinnamoyl-CoA:phenyllactate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate." [EC:2.8.3.17, RHEA:15601] +synonym: "(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity" EXACT [] +synonym: "FldA" RELATED [] +xref: EC:2.8.3.17 +xref: KEGG_REACTION:R07796 +xref: MetaCyc:2.8.3.17-RXN +xref: RHEA:15601 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0043786 +name: cinnamate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+." [PMID:10849007] +xref: EC:1.3.1 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043791 +name: dimethylamine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine." [PMID:9874228] +comment: This function is the first step in the pathway of methanogenesis from dimethylamine. +synonym: "dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] +synonym: "dimethylamine:corrinoid methyltransferase activity" EXACT [] +synonym: "DMA methyltransferase 1" EXACT [] +synonym: "DMAMT 1" EXACT [] +synonym: "MT1" BROAD [] +synonym: "mtbB1" RELATED [] +xref: EC:2.1.1.249 +xref: MetaCyc:RXN-8100 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043792 +name: enamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+)." [EC:3.5.2.18, RHEA:17209] +synonym: "6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity" EXACT [] +xref: EC:3.5.2.18 +xref: KEGG_REACTION:R07984 +xref: MetaCyc:3.5.2.18-RXN +xref: RHEA:17209 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0043793 +name: beta-ribofuranosylaminobenzene 5'-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate." [GOC:jl, PMID:12142414] +synonym: "beta-RFAP synthase activity" EXACT [] +xref: MetaCyc:RXN-8124 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0043794 +name: formate dehydrogenase (coenzyme F420) activity +namespace: molecular_function +def: "Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420." [PMID:3801411] +synonym: "formate dehydrogenase (F420) activity" EXACT [] +xref: EC:1.2.99 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0043795 +name: glyceraldehyde oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+)." [PMID:10095793, RHEA:36047] +xref: EC:1.2.99.8 +xref: RHEA:36047 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0043796 +name: glyceraldehyde dehydrogenase (NADP) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+." [EC:1.2.1.89] +xref: EC:1.2.1.89 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043797 +name: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin." [PMID:11265456, PMID:7721730, RHEA:24148] +synonym: "D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity" EXACT [] +synonym: "GAPOR" RELATED [] +synonym: "glyceraldehyde-3-phosphate Fd oxidoreductase activity" EXACT [EC:1.2.7.6] +synonym: "glyceraldehyde-3-phosphate ferredoxin reductase activity" EXACT [EC:1.2.7.6] +xref: EC:1.2.7.6 +xref: MetaCyc:1.2.7.6-RXN +xref: RHEA:24148 +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0043798 +name: glycerate 2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP." [MetaCyc:GKI-RXN, PMID:14413719] +synonym: "D-glycerate 2-kinase activity" EXACT [] +synonym: "glycerate kinase" BROAD [] +xref: EC:2.7.1 +xref: MetaCyc:GKI-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor + +[Term] +id: GO:0043799 +name: glycine oxidase activity +namespace: molecular_function +def: "Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide." [EC:1.4.3.19] +synonym: "glycine:oxygen oxidoreductase (deaminating)" EXACT [] +xref: EC:1.4.3.19 +xref: MetaCyc:1.4.3.19-RXN +xref: MetaCyc:RXN-8672 +xref: MetaCyc:RXN-8673 +xref: MetaCyc:RXN-8674 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0043800 +name: hexulose-6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate." [MetaCyc:R12-RXN, PMID:11839305] +synonym: "HUMPI" EXACT [] +xref: EC:5.3.1.27 +xref: MetaCyc:R12-RXN +xref: RHEA:25900 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0043801 +name: hexulose-6-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate." [PMID:16075199] +xref: EC:4.1.2.43 +xref: MetaCyc:R10-RXN +xref: RHEA:25201 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0043802 +name: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate." [EC:6.3.5.9, RHEA:12544] +synonym: "CobB" RELATED [] +synonym: "hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity" EXACT [] +synonym: "hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)" EXACT [] +xref: EC:6.3.5.9 +xref: KEGG_REACTION:R05224 +xref: MetaCyc:R341-RXN +xref: RHEA:12544 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0043803 +name: hydroxyneurosporene-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + spheroidene." [PMID:12664193, PMID:12770713, PMID:7358679, RHEA:30903] +synonym: "1-HO-carotenoid methylase" RELATED [EC:2.1.1.210] +synonym: "1-hydroxycarotenoid methylase" RELATED [EC:2.1.1.210] +synonym: "1-hydroxycarotenoid O-methylase" RELATED [EC:2.1.1.210] +synonym: "demethylspheroidene O-methyltransferase" RELATED [EC:2.1.1.210] +xref: EC:2.1.1.210 +xref: RHEA:30903 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043804 +name: imidazolone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one." [PMID:27286964, RHEA:24937] +comment: Note that this reaction can occur spontaneously (see RHEA:24937). +xref: RHEA:24937 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0043805 +name: indolepyruvate ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.8] +synonym: "3-(indol-3-yl)pyruvate synthase (ferredoxin) activity" EXACT [EC:1.2.7.8] +synonym: "3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)" EXACT [EC:1.2.7.8] +synonym: "indolepyruvate oxidoreductase activity" EXACT [EC:1.2.7.8] +synonym: "IOR" RELATED [] +xref: EC:1.2.7.8 +xref: MetaCyc:1.2.7.8-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0043806 +name: keto acid formate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate." [MetaCyc:KETOBUTFORMLY-RXN] +synonym: "keto-acid formate acetyltransferase" BROAD [] +synonym: "keto-acid formate lyase activity" EXACT [] +synonym: "keto-acid formate-lyase activity" EXACT [] +xref: EC:2.3.1 +xref: MetaCyc:KETOBUTFORMLY-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043807 +name: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.7] +synonym: "2-ketoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] +synonym: "2-oxoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] +synonym: "3-methyl-2-oxobutanoate synthase (ferredoxin) activity" EXACT [EC:1.2.7.7] +synonym: "3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)" EXACT [] +synonym: "branched-chain ketoacid ferredoxin reductase activity" RELATED [EC:1.2.7.7] +synonym: "branched-chain oxo acid ferredoxin reductase activity" RELATED [EC:1.2.7.7] +synonym: "keto-valine-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.7] +synonym: "ketoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] +synonym: "ketoisovalerate oxidoreductase activity" EXACT [EC:1.2.7.7] +synonym: "VOR" RELATED [] +xref: EC:1.2.7.7 +xref: MetaCyc:1.2.7.7-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0043808 +name: lyso-ornithine lipid acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein]." [PMID:15341653] +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0043810 +name: ornithine-acyl [acyl carrier protein] N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids." [PMID:15341653, RHEA:20633] +synonym: "L-ornithine N(alpha)-acyltransferase" EXACT [] +synonym: "ornithine-acyl[acyl carrier protein] N-acyltransferase activity" EXACT [] +xref: EC:2.3.2.30 +xref: RHEA:20633 +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0043811 +name: phosphate:acyl-[acyl carrier protein] acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein]." [IMG:01871] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043812 +name: phosphatidylinositol-4-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate." [PMID:10224048] +synonym: "phosphatidylinositol 4-phosphate phosphatase activity" EXACT [] +xref: EC:3.1.3 +is_a: GO:0034596 ! phosphatidylinositol phosphate 4-phosphatase activity +is_a: GO:0052744 ! phosphatidylinositol monophosphate phosphatase activity + +[Term] +id: GO:0043813 +name: phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate." [PMID:10806194, PMID:16607019] +synonym: "phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity" EXACT [] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1675836 "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane" +xref: Reactome:R-HSA-1676005 "PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane" +xref: Reactome:R-HSA-1676020 "PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane" +xref: Reactome:R-HSA-1676174 "PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane" +is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity +is_a: GO:0106018 ! phosphatidylinositol-3,5-bisphosphate phosphatase activity +relationship: part_of GO:0036092 ! phosphatidylinositol-3-phosphate biosynthetic process + +[Term] +id: GO:0043814 +name: phospholactate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate." [PMID:18260642] +xref: EC:2.7.7.68 +xref: MetaCyc:RXN-8077 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0043815 +name: phosphoribosylglycinamide formyltransferase 2 activity +namespace: molecular_function +def: "Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate." [EC:2.1.2.2, PMID:8117714] +synonym: "5'-phosphoribosylglycinamide transformylase 2" EXACT [] +synonym: "formate-dependent GAR transformylase activity" EXACT [] +synonym: "GAR transformylase 2" RELATED [] +synonym: "GART 2" RELATED [] +xref: MetaCyc:GARTRANSFORMYL2-RXN +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0043816 +name: phosphoserine-tRNA(Cys) ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys)." [PMID:17110438, RHEA:25678] +synonym: "O-phosphoseryl-tRNA(Cys) synthetase activity" EXACT [] +synonym: "phosphoserine--tRNA(Cys) ligase activity" EXACT [] +synonym: "phosphoserine-tRNACys ligase activity" EXACT [] +synonym: "SepRS" RELATED [] +xref: EC:6.1.1.27 +xref: RHEA:25678 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0043817 +name: phosphosulfolactate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite." [EC:4.4.1.19, RHEA:22784] +synonym: "(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)" EXACT [EC:4.4.1.19] +synonym: "(2R)-O-phospho-3-sulfolactate sulfo-lyase activity" EXACT [] +synonym: "(2R)-phospho-3-sulfolactate synthase activity" EXACT [EC:4.4.1.19] +synonym: "PSL synthase activity" EXACT [EC:4.4.1.19] +xref: EC:4.4.1.19 +xref: KEGG_REACTION:R07476 +xref: MetaCyc:4.4.1.19-RXN +xref: MetaCyc:R228-RXN +xref: RHEA:22784 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0043818 +name: precorrin-3B synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B." [EC:1.14.13.83, RHEA:17293] +synonym: "CobG" RELATED [] +synonym: "precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)" EXACT [] +synonym: "precorrin-3X synthase activity" EXACT [EC:1.14.13.83] +xref: EC:1.14.13.83 +xref: KEGG_REACTION:R05217 +xref: MetaCyc:R321-RXN +xref: RHEA:17293 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0043819 +name: precorrin-6A synthase (deacetylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X." [EC:2.1.1.152, RHEA:18261] +synonym: "CobF" RELATED [] +synonym: "precorrin-6X synthase (deacetylating) activity" EXACT [EC:2.1.1.152] +synonym: "S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)" EXACT [] +xref: EC:2.1.1.152 +xref: KEGG_REACTION:R05219 +xref: MetaCyc:R322-RXN +xref: RHEA:18261 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043820 +name: propionyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA." [PMID:12603323] +xref: EC:1.3.99 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0043821 +name: propionyl-CoA:succinate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate." [PMID:10769117] +synonym: "propionyl-CoA succinate CoA-transferase activity" EXACT [] +synonym: "propionyl-CoA:succinate CoA transferase activity" EXACT [] +xref: MetaCyc:RXN0-268 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0043822 +name: ribonuclease M5 activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor." [PMID:402365] +synonym: "5S ribosomal maturation nuclease activity" EXACT [EC:3.1.26.8] +synonym: "5S ribosomal RNA maturation endonuclease activity" EXACT [] +synonym: "RNase M5 activity" EXACT [EC:3.1.26.8] +xref: EC:3.1.26.8 +xref: MetaCyc:3.1.26.8-RXN +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0043823 +name: spheroidene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O." [PMID:16086104, PMID:16158287] +xref: EC:1.14.15.9 +xref: MetaCyc:RXN-10670 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0043824 +name: succinylglutamate-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH." [EC:1.2.1.71, RHEA:10812] +synonym: "AruD" RELATED [] +synonym: "AstD" RELATED [] +synonym: "N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.71] +synonym: "N-succinylglutamate 5-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.71] +synonym: "SGSD" RELATED [] +synonym: "succinyl glutamate-semialdehyde dehydrogenase activity" EXACT [] +synonym: "succinylglutamic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.71] +xref: EC:1.2.1.71 +xref: KEGG_REACTION:R05049 +xref: MetaCyc:SUCCGLUALDDEHYD-RXN +xref: RHEA:10812 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043825 +name: succinylornithine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate." [EC:2.6.1.81, RHEA:16953] +synonym: "2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [EC:2.6.1.81] +synonym: "AstC" RELATED [] +synonym: "N(2)-succinylornithine 5-aminotransferase activity" EXACT [EC:2.6.1.81] +synonym: "N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [] +synonym: "N2-succinylornithine 5-aminotransferase activity" EXACT [] +synonym: "SOAT" RELATED [] +synonym: "succinyl ornithine transaminase activity" EXACT [] +synonym: "succinyl-ornithine transaminase activity" EXACT [EC:2.6.1.81] +synonym: "succinylornithine aminotransferase activity" BROAD [EC:2.6.1.81] +xref: EC:2.6.1.81 +xref: KEGG_REACTION:R04217 +xref: MetaCyc:SUCCORNTRANSAM-RXN +xref: RHEA:16953 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043826 +name: sulfur oxygenase reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+." [PMID:1522063] +synonym: "SOR" RELATED [] +synonym: "sulphur oxygenase reductase activity" EXACT [] +xref: EC:1.13.11.55 +xref: MetaCyc:RXN-8226 +xref: RHEA:13957 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043827 +name: tRNA (adenine-57, 58-N(1)-) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA." [PMID:14739239] +synonym: "TrmI" RELATED [] +synonym: "tRNA (adenine-57, 58 N1-) methyltransferase activity" EXACT [] +synonym: "tRNA (adenine-57, 58-N1-) methyltransferase activity" EXACT [] +synonym: "tRNA (m1A) MTase" BROAD [] +is_a: GO:0016429 ! tRNA (adenine-N1-)-methyltransferase activity + +[Term] +id: GO:0043828 +name: tRNA 2-selenouridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA)." [PMID:14594807] +synonym: "B0503" RELATED [] +synonym: "SelU" RELATED [] +synonym: "YbbB" RELATED [] +xref: MetaCyc:RXN0-2281 +is_a: GO:0016785 ! transferase activity, transferring selenium-containing groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0043829 +name: tRNA-specific adenosine-37 deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule." [PMID:8915538, PMID:9707437] +synonym: "TAD1" RELATED [] +synonym: "tRNA(Ala)-A37 deaminase activity" EXACT [] +synonym: "tRNA-specific adenosine deaminase 1" EXACT [] +is_a: GO:0008251 ! tRNA-specific adenosine deaminase activity + +[Term] +id: GO:0043830 +name: thiol-driven fumarate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide." [PMID:2509466] +xref: EC:1.3.99 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0043831 +name: thiosulfate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate." [EC:1.8.5.2, RHEA:10936] +synonym: "DoxA" RELATED [] +synonym: "DoxD" RELATED [] +synonym: "thiosulfate oxidoreductase, tetrathionate-forming activity" EXACT [EC:1.8.5.2] +synonym: "thiosulfate:6-decylubiquinone oxidoreductase activity" EXACT [EC:1.8.5.2] +synonym: "thiosulfate:quinone oxidoreductase activity" EXACT [EC:1.8.5.2] +synonym: "thiosulphate dehydrogenase (quinone) activity" EXACT [] +synonym: "thiosulphate:quinone oxidoreductase activity" EXACT [] +synonym: "TQO" RELATED [] +xref: EC:1.8.5.2 +xref: KEGG_REACTION:R07177 +xref: MetaCyc:1.8.5.2-RXN +xref: RHEA:10936 +is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0043833 +name: methylamine-specific methylcobalamin:coenzyme M methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M." [MetaCyc:RXN-8099] +comment: This function is the second step in the pathway of methanogenesis from monomethylamine, dimethylamine and trimethylamine. +synonym: "methylamine-specific methylcobalamin:CoM methyltransferase activity" EXACT [] +synonym: "methylcobamide:coenzyme M methyltransferase activity" EXACT [] +synonym: "methylcobamide:CoM methyltransferase activity" EXACT [] +synonym: "methylcobamide:CoM methyltransferase II isozyme A" RELATED [] +synonym: "monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] +xref: EC:2.1.1.247 +xref: MetaCyc:RXN-8099 +xref: MetaCyc:RXN-8101 +xref: MetaCyc:RXN-8103 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043834 +name: trimethylamine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine." [PMID:9006042] +comment: This function is the first step in the pathway of methanogenesis from trimethylamine. +synonym: "MT1" BROAD [] +synonym: "mttB1" RELATED [] +synonym: "TMA methyltransferase 1" EXACT [] +synonym: "trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] +synonym: "trimethylamine:corrinoid methyltransferase activity" EXACT [] +xref: EC:2.1.1.250 +xref: MetaCyc:RXN-8102 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043835 +name: obsolete uracil/thymine dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor." [GOC:curators] +comment: This term was made obsolete because it represents two separate molecular functions. +synonym: "uracil oxidase activity" RELATED [EC:1.17.99.4] +synonym: "uracil-thymine oxidase activity" EXACT [EC:1.17.99.4] +synonym: "uracil/thymine dehydrogenase activity" EXACT [] +synonym: "uracil:acceptor oxidoreductase activity" NARROW [] +xref: EC:1.17.99.4 +is_obsolete: true +consider: GO:0050383 +consider: GO:0052620 + +[Term] +id: GO:0043836 +name: xanthine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate." [MetaCyc:R127-RXN, PMID:13278326] +synonym: "xanthinase activity" EXACT [] +xref: MetaCyc:R127-RXN +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0043837 +name: valine dehydrogenase (NAD) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH." [PMID:10612726, PMID:2803248] +synonym: "ValDH" RELATED [] +xref: EC:1.4.1.23 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043838 +name: phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol." [PMID:15795227] +comment: Note that Kdo is an abbreviation for 3-deoxy-D-manno-oct-2-ulosonic acid. +synonym: "EptB" RELATED [] +synonym: "phosphoethanolamine transferase" BROAD [] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0043839 +name: lipid A phosphate methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A." [PMID:15994324] +synonym: "lipid A 1-phosphomethyltransferase activity" EXACT [] +synonym: "lipid A methyltransferase" BROAD [] +synonym: "lipid A phosphomethyltransferase activity" EXACT [] +synonym: "LmtA" RELATED [] +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0043840 +name: branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine." [PMID:12670965] +synonym: "BCAT" RELATED [] +synonym: "branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity" EXACT [] +synonym: "branched-chain amino acid aminotransferase" BROAD [] +synonym: "branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity" EXACT [] +xref: MetaCyc:RXN-7708 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043841 +name: (S)-lactate 2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP." [PMID:11535063] +synonym: "lactate 2-kinase activity" EXACT [] +xref: MetaCyc:RXN-8076 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043842 +name: Kdo transferase activity +namespace: molecular_function +def: "Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP." [PMID:1577828, PMID:2033061, PMID:9195966] +synonym: "3-deoxy-D-manno-octulosonic-acid transferase activity" EXACT [] +synonym: "kdtA" RELATED [] +synonym: "WaaA" RELATED [] +xref: EC:2.4.99.12 +xref: EC:2.4.99.13 +xref: EC:2.4.99.14 +xref: EC:2.4.99.15 +xref: MetaCyc:KDOTRANS-RXN +xref: MetaCyc:KDOTRANS2-RXN +is_a: GO:0016740 ! transferase activity + +[Term] +id: GO:0043843 +name: ADP-specific glucokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate." [EC:2.7.1.147] +synonym: "ADP-dependent glucokinase activity" EXACT [EC:2.7.1.147] +synonym: "ADP:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.147] +xref: EC:2.7.1.147 +xref: Reactome:R-HSA-5696021 "ADPGK:Mg2+ phosphorylates Glc to G6P" +xref: RHEA:11460 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043844 +name: ADP-specific phosphofructokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate." [EC:2.7.1.146] +synonym: "ADP-6-phosphofructokinase activity" EXACT [EC:2.7.1.146] +synonym: "ADP-dependent phosphofructokinase activity" EXACT [EC:2.7.1.146] +synonym: "ADP-Pfk activity" EXACT [EC:2.7.1.146] +synonym: "ADP:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.146] +xref: EC:2.7.1.146 +xref: RHEA:20105 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043845 +name: DNA polymerase III, proofreading complex +namespace: cellular_component +def: "A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity." [PMID:16973612, Wikipedia:Pol_III] +synonym: "DNA polymerase III, proof-reading complex" EXACT [] +synonym: "DNA polymerase III, proof-reading subcomplex" EXACT [] +synonym: "DNA polymerase III, proofreading subcomplex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0044776 ! DNA polymerase III, core complex + +[Term] +id: GO:0043846 +name: DNA polymerase III, clamp loader complex +namespace: cellular_component +def: "A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands." [PMID:12940977] +synonym: "clamp loader complex" BROAD [] +synonym: "DNA polymerase III, DnaX complex" EXACT [] +synonym: "DNA polymerase III, DnaX subcomplex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0009360 ! DNA polymerase III complex + +[Term] +id: GO:0043847 +name: DNA polymerase III, clamp loader chi/psi subcomplex +namespace: cellular_component +def: "A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB)." [PMID:12940977] +synonym: "DNA polymerase III, DnaX complex, chi/psi subcomplex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043846 ! DNA polymerase III, clamp loader complex + +[Term] +id: GO:0043848 +name: obsolete excinuclease cho activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage." [PMID:11818552] +comment: This term was obsoleted because it represented a gene product. +synonym: "cho" RELATED [] +synonym: "endonuclease cho" EXACT [] +synonym: "uvrc homolog protein" RELATED [] +is_obsolete: true + +[Term] +id: GO:0043849 +name: Ras palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins." [PMID:16000296] +synonym: "DHHC cysteine-rich domain-containing protein ERF2" RELATED [] +synonym: "ERF2" RELATED [] +synonym: "palmitoyltransferase ERF2" RELATED [] +synonym: "Ras protein acyltransferase activity" EXACT [] +is_a: GO:0019706 ! protein-cysteine S-palmitoyltransferase activity + +[Term] +id: GO:0043850 +name: RecFOR complex +namespace: cellular_component +def: "A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair." [PMID:12769856] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0043851 +name: methanol-specific methylcobalamin:coenzyme M methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M." [IMG:01315, MetaCyc:RXN-8096] +comment: This function is the second step in the pathway of methanogenesis from methanol. +synonym: "methanol-specific methylcobalamin: coenzyme M methyltransferase activity" EXACT [] +synonym: "methanol-specific methylcobalamin:CoM methyltransferase activity" EXACT [] +synonym: "methyltransferase 2" BROAD [] +synonym: "MT2" BROAD [] +synonym: "MtaA" RELATED [] +synonym: "MtaC protein: coenzyme M methyltransferase activity" EXACT [] +synonym: "MtaC protein:coenzyme M methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-8096 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043852 +name: monomethylamine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3." [PMID:9195968] +comment: This function is the first step in the pathway of methanogenesis from monomethylamine. +synonym: "MMAMT" RELATED [] +synonym: "monomethylamine:corrinoid methyltransferase activity" EXACT [] +synonym: "MtmB" RELATED [] +xref: EC:2.1.1.248 +xref: MetaCyc:RXN-8098 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0043853 +name: methanol-CoM methyltransferase complex +namespace: cellular_component +def: "A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol." [PMID:9363780] +synonym: "methanol-coenzyme M methyltransferase complex" EXACT [] +synonym: "methanol: coenzyme M methyltransferase complex" EXACT [] +synonym: "methanol: CoM methyltransferase complex" EXACT [] +synonym: "methanol:coenzyme M methyltransferase complex" EXACT [] +synonym: "methanol:CoM methyltransferase complex" EXACT [] +xref: MetaCyc:CPLX-421 +is_a: GO:0034708 ! methyltransferase complex + +[Term] +id: GO:0043854 +name: cyclic nucleotide-gated mechanosensitive ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:jl, PMID:22206667] +synonym: "cyclic nucleotide gated mechanosensitive ion channel activity" EXACT [] +synonym: "cyclic nucleotide regulated mechanosensitive ion channel" EXACT [] +synonym: "cyclic nucleotide-regulated mechanosensitive ion channel" EXACT [] +synonym: "cyclic nucleotide-regulated small mechanosensitive ion channel" RELATED [] +synonym: "MscS" RELATED [] +synonym: "small conductance mechanosensitive ion channel" EXACT [] +is_a: GO:0008381 ! mechanosensitive ion channel activity + +[Term] +id: GO:0043855 +name: cyclic nucleotide-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:jl] +synonym: "cyclic nucleotide activated ion channel activity" EXACT [] +synonym: "cyclic nucleotide gated ion channel activity" EXACT [] +synonym: "cyclic nucleotide-activated ion channel activity" EXACT [] +is_a: GO:0015276 ! ligand-gated ion channel activity + +[Term] +id: GO:0043856 +name: anti-sigma factor antagonist activity +namespace: molecular_function +def: "The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity." [GOC:jl, GOC:txnOH, PMID:15576799] +synonym: "anti-anti-sigma factor activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: part_of GO:0045893 ! positive regulation of transcription, DNA-templated + +[Term] +id: GO:0043857 +name: N-acetylornithine carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate." [EC:2.1.3.9, RHEA:18609] +synonym: "acetylornithine transcarbamylase activity" EXACT [] +synonym: "AOTC" RELATED [] +synonym: "carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.9] +synonym: "carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.9] +synonym: "N-acetylornithine transcarbamylase activity" EXACT [] +xref: EC:2.1.3.9 +xref: KEGG_REACTION:R07245 +xref: MetaCyc:2.1.3.9-RXN +xref: RHEA:18609 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0043858 +name: arginine:ornithine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out)." [GOC:jl, PMID:17110979] +synonym: "ArcD" RELATED [] +synonym: "arginine-ornithine antiporter activity" EXACT [] +synonym: "arginine/ornithine antiporter activity" EXACT [] +is_a: GO:0015181 ! arginine transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0043859 +name: obsolete cyanophycinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides." [PMID:10429200] +comment: This term was made obsolete because it represents a gene product. +synonym: "cyanophycinase activity" EXACT [] +xref: EC:3 +is_obsolete: true +replaced_by: GO:0008236 + +[Term] +id: GO:0043860 +name: cyanophycin synthetase activity +namespace: molecular_function +def: "Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer)." [EC:6.3.2.29, EC:6.3.2.30, GOC:jl] +synonym: "cphA" RELATED [] +xref: EC:6.3.1 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0043861 +name: agmatine:putrescine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out)." [GOC:jl, PMID:17028272] +synonym: "agmatine-putrescine antiporter activity" EXACT [] +synonym: "agmatine/putrescine antiporter activity" EXACT [] +is_a: GO:0015489 ! putrescine transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0043862 +name: arginine:agmatine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out)." [GOC:jl, PMID:17099215] +synonym: "AdiC" RELATED [] +synonym: "arginine-agmatine antiporter activity" EXACT [] +synonym: "arginine-agmatine exchange transporter activity" EXACT [] +synonym: "arginine/agmatine antiporter activity" EXACT [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015181 ! arginine transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0043863 +name: 4-hydroxy-2-ketopimelate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate." [MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN] +synonym: "2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity" EXACT [] +synonym: "HHED aldolase activity" EXACT [] +synonym: "HpaI" RELATED [] +synonym: "HpcH" RELATED [] +xref: MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0043864 +name: indoleacetamide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA." [GOC:jl, MetaCyc:RXNN-404] +synonym: "IaaH" RELATED [] +synonym: "IAH" EXACT [] +synonym: "indole acetamide hydrolase activity" EXACT [] +synonym: "indole-3-acetamide hydrolase activity" EXACT [] +synonym: "Tms2" RELATED [] +xref: EC:3.5.1.4 +xref: MetaCyc:G-5841 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0043865 +name: methionine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1990240 +def: "Enables the transfer of methionine from one side of a membrane to the other." [GOC:jl] +synonym: "methionine importer" RELATED [] +synonym: "methionine importer activity" NARROW [] +synonym: "methionine importing activity" NARROW [] +synonym: "methionine-importing activity" NARROW [] +is_a: GO:0000099 ! sulfur amino acid transmembrane transporter activity +is_a: GO:0008324 ! cation transmembrane transporter activity +relationship: part_of GO:0015821 ! methionine transport +created_by: pr +creation_date: 2013-11-15T10:35:04Z + +[Term] +id: GO:0043866 +name: adenylyl-sulfate reductase (thioredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin." [EC:1.8.4.10] +synonym: "AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [] +synonym: "AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.10] +synonym: "thioredoxin-dependent 5'-adenylylsulfate reductase activity" EXACT [] +xref: EC:1.8.4.10 +xref: RHEA:21976 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0043867 +name: 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine." [PMID:16407303, PMID:7748953] +synonym: "archaeal tRNA-guanine transglycosylase activity" EXACT [] +synonym: "archaeosine tRNA-ribosyltransferase activity" EXACT [] +synonym: "TgtA" RELATED [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0043870 +name: N-acetyl-gamma-aminoadipyl-phosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH." [MetaCyc:RXN-5183] +comment: This function is part of the prokaryotic alpha-aminoadipate lysine biosynthesis pathway. +synonym: "AGPR" RELATED [] +synonym: "ArgC" RELATED [] +synonym: "LysY" RELATED [] +synonym: "N-acetyl-alpha-glutamyl-phosphate reductase activity" EXACT [] +synonym: "N-acetyl-aminoadipate semialdehyde dehydrogenase activity" EXACT [] +synonym: "NAGSA dehydrogenase activity" BROAD [] +xref: MetaCyc:RXN-5183 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043871 +name: delta1-piperideine-6-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate." [MetaCyc:RXN-8162, PMID:16237033] +comment: This function is part of the pipecolate pathway of lysine catabolism. +synonym: "AmaB" RELATED [] +synonym: "PIPOX" RELATED [] +xref: MetaCyc:RXN-8162 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043872 +name: lysine:cadaverine antiporter activity +namespace: molecular_function +alt_id: GO:0015490 +alt_id: GO:0015497 +def: "Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out)." [GOC:jl, PMID:10986235, TC:2.A.3.2.2] +synonym: "cadaverine transmembrane transporter activity" NARROW [] +synonym: "cadaverine:lysine antiporter activity" EXACT [] +synonym: "lysine-cadaverine antiporter activity" EXACT [] +synonym: "lysine/cadaverine antiporter activity" EXACT [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015171 ! amino acid transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity + +[Term] +id: GO:0043873 +name: pyruvate-flavodoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin." [PMID:6352705] +synonym: "NifJ" RELATED [] +synonym: "pyruvate:flavodoxin oxidoreductase activity" EXACT [] +xref: MetaCyc:PYFLAVOXRE-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0043874 +name: acireductone synthase activity +namespace: molecular_function +def: "Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate." [EC:3.1.3.77, RHEA:21700] +comment: This function is involved in the process of methionine salvage. +synonym: "5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)" EXACT [EC:3.1.3.77] +synonym: "E-1" RELATED [] +synonym: "E-1 enolase-phosphatase" BROAD [] +xref: EC:3.1.3.77 +xref: MetaCyc:3.1.3.77-RXN +xref: Reactome:R-HSA-1237129 "Acireductone is created" +xref: RHEA:21700 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0043875 +name: 2-ketobutyrate formate-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate." [MetaCyc:KETOBUTFORMLY-RXN, PMID:9484901] +comment: This function is part of an anaerobic pathway for the catabolism of L-threonine. +synonym: "keto-acid formate acetyltransferase" BROAD [] +synonym: "KFL" EXACT [] +synonym: "TdcE" RELATED [] +xref: MetaCyc:KETOBUTFORMLY-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043876 +name: D-threonine aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde." [MetaCyc:4.1.2.42-RXN, PMID:9642221] +synonym: "D-allo-TA" EXACT [] +synonym: "D-allo-threonine aldolase activity" EXACT [] +synonym: "D-TA" EXACT [] +synonym: "DtaAS" RELATED [] +synonym: "low-specificity D-threonine aldolase" NARROW [] +xref: EC:4.1.2.42 +xref: MetaCyc:4.1.2.42-RXN +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0043877 +name: galactosamine-6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3." [PMID:10931310] +comment: This function is part of the pathway of N-acetyl-galactosamine and galactosamine utilization. +synonym: "AgaI" RELATED [] +synonym: "galactosamine-6-phosphate deaminase activity" EXACT [] +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0043878 +name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+." [PMID:9497334] +synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity" EXACT [] +synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD) activity" EXACT [] +synonym: "NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] +synonym: "non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)" EXACT [] +xref: EC:1.2.1.3 +xref: MetaCyc:RXN-3443 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043879 +name: glycolate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA)." [GOC:jl] +synonym: "glcA" RELATED [] +synonym: "glycolate permease" RELATED [] +synonym: "glycolic acid transmembrane transporter activity" EXACT [] +synonym: "hydroxyacetic acid transmembrane transporter activity" EXACT [] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +relationship: part_of GO:0097339 ! glycolate transmembrane transport + +[Term] +id: GO:0043880 +name: crotonyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reduction of crotonyl-CoA to butyryl-CoA." [InterPro:IPR010085, PMID:11162231] +synonym: "CCR" EXACT [] +synonym: "crotonyl-coenzyme A reductase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043881 +name: mesaconyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA." [PMID:16856935, PMID:16856937] +comment: This function is part of an alternate glyoxylate cycle for acetate assimilation. +synonym: "beta-methylmalyl-CoA dehydratase activity" EXACT [] +synonym: "mch" RELATED [] +synonym: "mesaconyl-coenzyme A hydratase activity" EXACT [] +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043882 +name: malate:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in)." [GOC:jl, PMID:10903309] +synonym: "malate Na(+) symporter activity" EXACT [] +synonym: "malate-sodium symporter activity" EXACT [] +synonym: "malate/sodium cotransporter activity" BROAD [] +synonym: "malate/sodium symporter activity" EXACT [] +synonym: "malate:Na+ symporter activity" EXACT [] +synonym: "malate:sodium cotransporter activity" BROAD [] +synonym: "Na(+)-malate symporter activity" EXACT [] +synonym: "Na+:malate symporter activity" EXACT [] +synonym: "sodium-dependent malate transporter" BROAD [] +synonym: "sodium/malate symporter activity" EXACT [] +synonym: "sodium:malate symporter activity" EXACT [] +is_a: GO:0015140 ! malate transmembrane transporter activity +is_a: GO:0017153 ! sodium:dicarboxylate symporter activity + +[Term] +id: GO:0043883 +name: malolactic enzyme activity +namespace: molecular_function +def: "Catalysis of the reaction: malate + H+ = L-lactate + CO2." [MetaCyc:RXN8E-5623, PMID:3139053] +comment: This function is part of the process of degradation of L-malic acid by lactic acid bacteria. +synonym: "MleS" RELATED [] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043884 +name: CO-methylating acetyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA." [EC:2.3.1.169, PMID:1748656] +synonym: "acetyl-CoA synthase activity" BROAD [] +synonym: "acetyl-CoA:corrinoid protein O-acetyltransferase activity" EXACT [] +synonym: "ACS" RELATED [EC:2.3.1.169] +synonym: "CO-methylating acetyl-coenzyme A synthase activity" EXACT [] +xref: EC:2.3.1.169 +xref: MetaCyc:ACETYLSYNCLTH-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0043885 +name: carbon-monoxide dehydrogenase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin." [EC:1.2.7.4] +synonym: "carbon monoxide dehydrogenase (ferredoxin) activity" EXACT [] +synonym: "carbon monoxide dehydrogenase activity" BROAD [] +synonym: "carbon-monoxide dehydrogenase activity" BROAD [EC:1.2.7.4] +synonym: "carbon-monoxide,water:ferredoxin oxidoreductase activity" EXACT [] +synonym: "carbon-monoxide:(acceptor) oxidoreductase activity" EXACT [] +synonym: "CO dehydrogenase activity" EXACT [] +synonym: "CO-dehydrogenase (ferredoxin) activity" EXACT [] +synonym: "CO-dehydrogenase activity" EXACT [] +synonym: "CODH" RELATED [] +xref: EC:1.2.7.4 +xref: MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0043886 +name: structural constituent of carboxysome +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide." [GOC:jl] +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0031470 ! carboxysome +relationship: occurs_in GO:0031470 ! carboxysome + +[Term] +id: GO:0043887 +name: melibiose:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in)." [PMID:1970646] +synonym: "MelB" RELATED [] +synonym: "melibiose carrier protein" RELATED [] +synonym: "melibiose permease" BROAD [] +synonym: "melibiose-Na+ symporter activity" EXACT [] +synonym: "melibiose-sodium symporter activity" EXACT [] +synonym: "melibiose/Na+ symporter activity" EXACT [] +synonym: "melibiose/sodium symporter activity" EXACT [] +synonym: "melibiose:Na+ symporter activity" EXACT [] +synonym: "Na+ (Li+)/melibiose symporter activity" EXACT [] +synonym: "Na+-melibiose symporter activity" EXACT [] +synonym: "Na+/melibiose symporter activity" EXACT [] +synonym: "Na+:melibiose symporter activity" EXACT [] +synonym: "sodium-melibiose symporter activity" EXACT [] +synonym: "sodium/melibiose symporter activity" EXACT [] +synonym: "sodium:melibiose symporter activity" EXACT [] +synonym: "thiomethylgalactoside permease II" RELATED [] +is_a: GO:0015370 ! solute:sodium symporter activity +is_a: GO:0015487 ! melibiose:cation symporter activity + +[Term] +id: GO:0043888 +name: (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate." [PMID:15356000, PMID:16494480] +comment: This function is involved in archaeal lipid synthesis. +synonym: "2,3-dGGGPS" EXACT [] +synonym: "DGGGP synthase activity" EXACT [] +synonym: "DGGGPS" EXACT [] +synonym: "UbiA" RELATED [] +xref: EC:2.5.1 +is_a: GO:0002094 ! polyprenyltransferase activity +is_a: GO:0004337 ! geranyltranstransferase activity + +[Term] +id: GO:0043889 +name: (S)-3-O-geranylgeranylglyceryl phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate." [PMID:12801917, PMID:17253090, PMID:8408023] +comment: This function is involved in archaeal lipid synthesis. +synonym: "(S)-3-O-geranylgeranylglycerylphosphate synthase activity" EXACT [] +synonym: "(S)-GGGP synthase activity" EXACT [] +synonym: "GGGP synthase activity" EXACT [] +synonym: "GGGPS" EXACT [] +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0043890 +name: N-acetylgalactosamine-6-sulfatase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate." [EC:3.1.6.4] +synonym: "acetylgalactosamine 6-sulfatase activity" EXACT [] +synonym: "chondroitin sulfatase" BROAD [] +synonym: "chondroitinase" BROAD [] +synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.4] +synonym: "galactose-6-sulfate sulfatase activity" EXACT [] +synonym: "N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity" EXACT [] +synonym: "N-acetylgalactosamine 6-sulfatase activity" EXACT [] +synonym: "N-acetylgalactosamine-6-sulfate sulfatase activity" EXACT [] +xref: EC:3.1.6.4 +xref: MetaCyc:3.1.6.4-RXN +xref: Reactome:R-HSA-1630304 "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate" +xref: Reactome:R-HSA-2263490 "Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate" +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0043891 +name: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+." [EC:1.2.1.59] +synonym: "D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)" EXACT [] +synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)" EXACT [] +synonym: "NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.59] +synonym: "triosephosphate dehydrogenase (NAD(P))" EXACT [] +synonym: "triosephosphate dehydrogenase (NAD(P)+)" EXACT [EC:1.2.1.59] +xref: EC:1.2.1.59 +xref: MetaCyc:GAPDHSYNEC-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043892 +name: methylglyoxal reductase (NADPH-dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+." [EC:1.1.1.283] +synonym: "Gre2" RELATED [] +synonym: "lactaldehyde dehydrogenase (NADP+)" EXACT [] +synonym: "lactaldehyde:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.283] +xref: EC:1.1.1.283 +xref: MetaCyc:1.1.1.283-RXN +xref: MetaCyc:RXN-8636 +xref: RHEA:21748 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043893 +name: acetate:cation symporter activity +namespace: molecular_function +def: "Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in)." [GOC:jl, PMID:14563880] +synonym: "acetate permease" BROAD [] +synonym: "acetate-cation symporter activity" EXACT [] +synonym: "acetate/cation symporter activity" EXACT [] +synonym: "ActP" RELATED [] +synonym: "cation-acetate symporter activity" EXACT [] +synonym: "cation/acetate symporter activity" EXACT [] +synonym: "cation:acetate symporter activity" EXACT [] +is_a: GO:0015123 ! acetate transmembrane transporter activity +is_a: GO:0015294 ! solute:cation symporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity + +[Term] +id: GO:0043894 +name: acetyl-CoA synthetase acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate." [PMID:15236963] +synonym: "Pat" RELATED [] +synonym: "Pat enzyme" EXACT [] +synonym: "protein acetyltransferase activity" BROAD [] +is_a: GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0043895 +name: cyclomaltodextrin glucanotransferase activity +namespace: molecular_function +def: "Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond." [EC:2.4.1.19] +synonym: "1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)" EXACT [] +synonym: "alpha-1,4-glucan 4-glycosyltransferase, cyclizing" RELATED [] +synonym: "alpha-cyclodextrin glucanotransferase" RELATED [] +synonym: "alpha-cyclodextrin glycosyltransferase" RELATED [] +synonym: "Bacillus macerans amylase" RELATED [] +synonym: "beta-cyclodextrin glucanotransferase" RELATED [] +synonym: "beta-cyclodextrin glycosyltransferase" RELATED [] +synonym: "BMA" RELATED [] +synonym: "CGTase" RELATED [] +synonym: "cyclodextrin glucanotransferase" BROAD [] +synonym: "cyclodextrin glycosyltransferase" RELATED [] +synonym: "cyclomaltodextrin glucotransferase" RELATED [] +synonym: "cyclomaltodextrin glycosyltransferase" RELATED [] +synonym: "gamma-cyclodextrin glycosyltransferase" RELATED [] +synonym: "konchizaimu" RELATED [] +synonym: "neutral-cyclodextrin glycosyltransferase" RELATED [] +xref: EC:2.4.1.19 +xref: MetaCyc:2.4.1.19-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0043896 +name: glucan 1,6-alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides." [EC:3.2.1.70] +synonym: "exo-1,6-alpha-glucosidase activity" EXACT [EC:3.2.1.70] +synonym: "exo-1,6-beta-glucosidase" RELATED [] +synonym: "glucan alpha-1,6-D-glucohydrolase activity" EXACT [EC:3.2.1.70] +synonym: "glucan-1,6-alpha-glucosidase activity" EXACT [] +synonym: "glucodextranase activity" EXACT [EC:3.2.1.70] +synonym: "glucodextrinase" BROAD [] +xref: EC:3.2.1.70 +xref: MetaCyc:3.2.1.70-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0043897 +name: glucan 1,4-alpha-maltohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains." [EC:3.2.1.133] +synonym: "1,4-alpha-D-glucan alpha-maltohydrolase activity" EXACT [] +synonym: "glucan-1,4-alpha-maltohydrolase activity" EXACT [] +synonym: "maltogenic alpha-amylase activity" EXACT [] +xref: EC:3.2.1.133 +xref: MetaCyc:3.2.1.133-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0043898 +name: 2,3-dihydroxybiphenyl 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid." [GOC:jl, PMID:15715866] +synonym: "2,3-dihydroxybiphenyl-1,2-dioxygenase activity" EXACT [] +synonym: "BphC" RELATED [] +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0043899 +name: phosphoserine:homoserine phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine." [GOC:jl, PMID:14699121] +synonym: "thrH" RELATED [] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0043900 +name: regulation of multi-organism process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species." [GOC:jl] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051704 ! multi-organism process +relationship: regulates GO:0051704 ! multi-organism process + +[Term] +id: GO:0043901 +name: negative regulation of multi-organism process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species." [GOC:jl] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051704 ! multi-organism process +relationship: negatively_regulates GO:0051704 ! multi-organism process + +[Term] +id: GO:0043902 +name: positive regulation of multi-organism process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species." [GOC:jl] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051704 ! multi-organism process +relationship: positively_regulates GO:0051704 ! multi-organism process + +[Term] +id: GO:0043903 +name: regulation of interspecies interactions between organisms +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association." [GOC:jl] +synonym: "regulation of symbiosis, encompassing mutualism through parasitism" RELATED [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044403 ! symbiotic process +relationship: regulates GO:0044403 ! symbiotic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19222 xsd:anyURI + +[Term] +id: GO:0043904 +name: isochorismate pyruvate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: isochorismate = salicylate + pyruvate." [GOC:jl, PMID:16248620] +synonym: "IPL" EXACT [] +synonym: "isochorismate-pyruvate lyase activity" EXACT [] +xref: EC:4.2.99.21 +xref: MetaCyc:RXN-1981 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0043905 +name: Ser-tRNA(Thr) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr)." [GOC:jl, PMID:15240874] +synonym: "Ser-tRNAThr hydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0043906 +name: Ala-tRNA(Pro) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro)." [GOC:jl, PMID:14663147] +synonym: "Ala-tRNAPro hydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0002161 ! aminoacyl-tRNA editing activity + +[Term] +id: GO:0043907 +name: Cys-tRNA(Pro) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro)." [GOC:jl, PMID:15886196] +synonym: "Cys-tRNA(Pro) deacetylase activity" EXACT [] +synonym: "Cys-tRNAPro hydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0002161 ! aminoacyl-tRNA editing activity + +[Term] +id: GO:0043908 +name: Ser(Gly)-tRNA(Ala) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala)." [GOC:jl, PMID:14663147] +synonym: "Ser(Gly)-tRNAAla hydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0043909 +name: N-acetylcitrulline deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate." [GOC:jl, PMID:16750290, RHEA:61092] +synonym: "acetylcitrulline deacetylase activity" EXACT [] +synonym: "N-acetyl-L-citrulline deacetylase activity" EXACT [] +xref: RHEA:61092 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0043910 +name: ATP:coenzyme F420 adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate." [GOC:jl, MetaCyc:RXN-9385, PMID:7957247, PMID:8550473] +synonym: "ATP:coenzyme F420 adenyltransferase activity" EXACT [] +synonym: "coenzyme F390-A synthetase activity" EXACT [] +xref: MetaCyc:RXN-9385 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0043911 +name: D-lysine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate." [GOC:jl, PMID:17259313] +synonym: "D-lysine aminotransferase activity" EXACT [] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0043912 +name: D-lysine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide." [GOC:jl, PMID:17259313] +xref: EC:1.4.3 +is_a: GO:0003884 ! D-amino-acid oxidase activity + +[Term] +id: GO:0043913 +name: chromosome segregation-directing complex +namespace: cellular_component +def: "A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology." [GOC:jl, PMID:15612918] +synonym: "chromosome segregation directing complex" EXACT [] +synonym: "longitudinal peptidoglycan synthesis-directing complex" EXACT [] +synonym: "MreBCD complex" NARROW [] +is_a: GO:0098796 ! membrane protein complex + +[Term] +id: GO:0043914 +name: NADPH:sulfur oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+." [GOC:jl, PMID:17449625] +synonym: "CoA-dependent NAD(P)H sulfur oxidoreductase activity" EXACT [] +synonym: "coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity" EXACT [] +synonym: "NAD(P)H elemental sulfur oxidoreductase activity" EXACT [] +synonym: "NAD(P)H sulfur oxidoreductase activity" EXACT [] +synonym: "NAD(P)H sulphur oxidoreductase activity" EXACT [] +synonym: "NAD(P)H:sulfur oxidoreductase activity" EXACT [] +synonym: "NADPH:sulphur oxidoreductase activity" EXACT [] +synonym: "NSR" EXACT [] +xref: EC:1.8.1.18 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0043915 +name: L-seryl-tRNA(Sec) kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec)." [GOC:jl, PMID:16201757, RHEA:25037] +synonym: "O-phosphoseryl-tRNA(Sec) kinase activity" EXACT [] +xref: EC:2.7.1.164 +xref: MetaCyc:RXN-10038 +xref: RHEA:25037 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0043916 +name: DNA-7-methylguanine glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site." [GOC:jl, PMID:16468998] +xref: EC:3.2.2.21 +xref: MetaCyc:3.2.2.21-RXN +is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity + +[Term] +id: GO:0043917 +name: ribose 1,5-bisphosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate." [GOC:jl] +synonym: "ribose-1,5-bisphosphate isomerase activity" EXACT [] +xref: EC:5.3.1.29 +xref: MetaCyc:RXN-8801 +xref: RHEA:32243 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0043918 +name: cadaverine aminopropyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine." [GOC:jl, PMID:17545282] +synonym: "cadaverine aminopropyl transferase activity" EXACT [] +xref: EC:2.5.1.104 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0043919 +name: agmatine aminopropyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine." [GOC:jl, PMID:15983049] +synonym: "agmatine aminopropyl transferase activity" EXACT [] +xref: EC:2.5.1.104 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0043920 +name: aminopropylagmatine ureohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea." [GOC:jl, PMID:15983049] +xref: RHEA:35828 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0043921 +name: modulation by host of viral transcription +namespace: biological_process +def: "Any process in which a host organism modulates the frequency, rate or extent of viral transcription." [GOC:jl] +synonym: "regulation by host of viral transcription" EXACT [] +synonym: "regulation of viral transcription by host" EXACT [] +is_a: GO:0043922 ! negative regulation by host of viral transcription +is_a: GO:0044793 ! negative regulation by host of viral process +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: negatively_regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0043922 +name: negative regulation by host of viral transcription +namespace: biological_process +def: "Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription." [GOC:jl] +synonym: "negative regulation of viral transcription by host" EXACT [] +is_a: GO:0032897 ! negative regulation of viral transcription +is_a: GO:0051851 ! modulation by host of symbiont process +intersection_of: GO:0051851 ! modulation by host of symbiont process +intersection_of: negatively_regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0043923 +name: positive regulation by host of viral transcription +namespace: biological_process +def: "Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA." [GOC:jl] +synonym: "positive regulation of viral transcription by host" EXACT [] +is_a: GO:0050434 ! positive regulation of viral transcription +is_a: GO:0051851 ! modulation by host of symbiont process +intersection_of: GO:0051851 ! modulation by host of symbiont process +intersection_of: positively_regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0043924 +name: suramin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms." [GOC:jl, Wikipedia:Suramin] +synonym: "Germanin binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0043168 ! anion binding +is_a: GO:0043177 ! organic acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0043927 +name: exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap." [GOC:mtg_mpo] +is_a: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: part_of GO:0000294 ! nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay +relationship: part_of GO:0000294 ! nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay + +[Term] +id: GO:0043928 +name: exonucleolytic catabolism of deadenylated mRNA +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail." [GOC:mtg_mpo] +is_a: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: part_of GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +relationship: part_of GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay + +[Term] +id: GO:0043929 +name: primary ovarian follicle growth involved in double layer follicle stage +namespace: biological_process +def: "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis." [GOC:mtg_mpo] +synonym: "primary ovarian follicle growth during double layer follicle stage" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001545 ! primary ovarian follicle growth +intersection_of: GO:0001545 ! primary ovarian follicle growth +intersection_of: part_of GO:0048161 ! double layer follicle stage +relationship: part_of GO:0048161 ! double layer follicle stage + +[Term] +id: GO:0043930 +name: primary ovarian follicle growth involved in primary follicle stage +namespace: biological_process +def: "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis." [GOC:mtg_mpo] +synonym: "primary ovarian follicle growth during primary follicle stage" RELATED [GOC:dph, GOC:tb] +is_a: GO:0001545 ! primary ovarian follicle growth +intersection_of: GO:0001545 ! primary ovarian follicle growth +intersection_of: part_of GO:0048160 ! primary follicle stage +relationship: part_of GO:0048160 ! primary follicle stage + +[Term] +id: GO:0043931 +name: ossification involved in bone maturation +namespace: biological_process +def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo] +synonym: "ossification involved in bone modeling" NARROW [GO_REF:0000034] +synonym: "ossification involved in skeletal development" EXACT [GOC:dph] +is_a: GO:0001503 ! ossification +intersection_of: GO:0001503 ! ossification +intersection_of: part_of GO:0070977 ! bone maturation +relationship: part_of GO:0070977 ! bone maturation + +[Term] +id: GO:0043932 +name: ossification involved in bone remodeling +namespace: biological_process +def: "The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli." [GO_REF:0000034, GOC:mtg_mpo] +synonym: "ossification involved in bone remodelling" RELATED [] +is_a: GO:0001503 ! ossification +intersection_of: GO:0001503 ! ossification +intersection_of: part_of GO:0046849 ! bone remodeling +relationship: part_of GO:0046849 ! bone remodeling + +[Term] +id: GO:0043933 +name: protein-containing complex subunit organization +namespace: biological_process +alt_id: GO:0034600 +alt_id: GO:0034621 +alt_id: GO:0071822 +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah] +synonym: "cellular macromolecular complex organization" RELATED [] +synonym: "cellular macromolecular complex subunit organisation" RELATED [] +synonym: "cellular macromolecular complex subunit organization" RELATED [] +synonym: "macromolecular complex organization" RELATED [] +synonym: "macromolecular complex subunit organisation" RELATED [] +synonym: "macromolecular complex subunit organization" RELATED [] +synonym: "protein complex subunit organisation" EXACT [GOC:mah] +synonym: "protein complex subunit organization" EXACT [] +is_a: GO:0016043 ! cellular component organization +created_by: mah +creation_date: 2010-09-08T10:01:42Z + +[Term] +id: GO:0043934 +name: sporulation +namespace: biological_process +def: "The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction." [GOC:pamgo_curators] +subset: goslim_metagenomics +subset: goslim_yeast +xref: Wikipedia:Spore +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0043935 +name: sexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction." [GOC:pamgo_curators] +is_a: GO:0030435 ! sporulation resulting in formation of a cellular spore +is_a: GO:0034293 ! sexual sporulation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0030435 ! sporulation resulting in formation of a cellular spore +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0043936 +name: asexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction." [GOC:pamgo_curators] +synonym: "asexual reproduction resulting in the formation of a cellular spore" EXACT [GOC:di] +synonym: "asexual sporulation resulting in the formation of a viable spore" BROAD [GOC:di] +is_a: GO:0030435 ! sporulation resulting in formation of a cellular spore +is_a: GO:0030436 ! asexual sporulation + +[Term] +id: GO:0043937 +name: regulation of sporulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." [GOC:pamgo_curators] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043934 ! sporulation +relationship: regulates GO:0043934 ! sporulation + +[Term] +id: GO:0043938 +name: positive regulation of sporulation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." [GOC:pamgo_curators] +is_a: GO:0043937 ! regulation of sporulation +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043934 ! sporulation +relationship: positively_regulates GO:0043934 ! sporulation + +[Term] +id: GO:0043939 +name: negative regulation of sporulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure." [GOC:pamgo_curators] +is_a: GO:0043937 ! regulation of sporulation +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043934 ! sporulation +relationship: negatively_regulates GO:0043934 ! sporulation + +[Term] +id: GO:0043940 +name: regulation of sexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis." [GOC:pamgo_curators] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0034306 ! regulation of sexual sporulation +is_a: GO:0042173 ! regulation of sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore +relationship: regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043941 +name: positive regulation of sexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis." [GOC:pamgo_curators] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0045881 ! positive regulation of sporulation resulting in formation of a cellular spore +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore +relationship: positively_regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043942 +name: negative regulation of sexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis." [GOC:pamgo_curators] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0042174 ! negative regulation of sporulation resulting in formation of a cellular spore +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore +relationship: negatively_regulates GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043943 +name: regulation of asexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis." [GOC:pamgo_curators] +is_a: GO:0034305 ! regulation of asexual sporulation +is_a: GO:0042173 ! regulation of sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore +relationship: regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043944 +name: negative regulation of asexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis." [GOC:pamgo_curators] +is_a: GO:0042174 ! negative regulation of sporulation resulting in formation of a cellular spore +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:1903665 ! negative regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore +relationship: negatively_regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043945 +name: positive regulation of asexual sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis." [GOC:pamgo_curators] +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0045881 ! positive regulation of sporulation resulting in formation of a cellular spore +is_a: GO:1903666 ! positive regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore +relationship: positively_regulates GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0043946 +name: positive regulation of catalytic activity in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "activation of enzyme activity in other organism" NARROW [] +synonym: "activation of enzyme activity in other organism during symbiotic interaction" NARROW [] +synonym: "positive regulation of catalytic activity in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "up regulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +synonym: "up-regulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +synonym: "upregulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +is_a: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction + +[Term] +id: GO:0043947 +name: positive regulation by host of symbiont catalytic activity +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "activation by host of symbiont enzyme activity" NARROW [] +synonym: "activation of symbiont enzyme activity" NARROW [] +synonym: "positive regulation by host of symbiont enzyme activity" EXACT [] +synonym: "up regulation by host of symbiont enzyme activity" EXACT [] +synonym: "up-regulation by host of symbiont enzyme activity" EXACT [] +synonym: "upregulation by host of symbiont enzyme activity" EXACT [] +is_a: GO:0043946 ! positive regulation of catalytic activity in other organism involved in symbiotic interaction +is_a: GO:0052422 ! modulation by host of symbiont catalytic activity + +[Term] +id: GO:0043948 +name: induction by symbiont of host catalytic activity +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host enzyme activity" NARROW [] +synonym: "activation of host enzyme activity" NARROW [] +synonym: "positive regulation by symbiont of host catalytic activity" EXACT [] +synonym: "positive regulation by symbiont of host enzyme activity" EXACT [] +synonym: "up regulation by symbiont of host enzyme activity" EXACT [] +synonym: "up-regulation by symbiont of host enzyme activity" EXACT [] +synonym: "upregulation by symbiont of host enzyme activity" EXACT [] +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0043946 ! positive regulation of catalytic activity in other organism involved in symbiotic interaction +is_a: GO:0052148 ! modulation by symbiont of host catalytic activity +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: positively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0043949 +name: regulation of cAMP-mediated signaling +namespace: biological_process +def: "Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response." [GOC:jl] +synonym: "regulation of cAMP-mediated signalling" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019933 ! cAMP-mediated signaling +relationship: regulates GO:0019933 ! cAMP-mediated signaling + +[Term] +id: GO:0043950 +name: positive regulation of cAMP-mediated signaling +namespace: biological_process +def: "Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response." [GOC:jl] +synonym: "positive regulation of cAMP-mediated signalling" EXACT [] +is_a: GO:0043949 ! regulation of cAMP-mediated signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019933 ! cAMP-mediated signaling +relationship: positively_regulates GO:0019933 ! cAMP-mediated signaling + +[Term] +id: GO:0043951 +name: negative regulation of cAMP-mediated signaling +namespace: biological_process +def: "Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response." [GOC:jl] +synonym: "negative regulation of cAMP-mediated signalling" EXACT [] +is_a: GO:0043949 ! regulation of cAMP-mediated signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019933 ! cAMP-mediated signaling +relationship: negatively_regulates GO:0019933 ! cAMP-mediated signaling + +[Term] +id: GO:0043952 +name: protein transport by the Sec complex +namespace: biological_process +def: "The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'protein secretion by the type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported. +synonym: "protein secretion by the Sec complex" NARROW [] +synonym: "protein translocation by the Sec complex" NARROW [] +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0043953 +name: protein transport by the Tat complex +namespace: biological_process +def: "The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex." [GOC:pamgo_curators] +comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'TAT protein translocation system complex ; GO:0033281'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported. +synonym: "protein secretion by the TAT complex" NARROW [] +synonym: "protein translocation by the TAT complex" NARROW [] +synonym: "protein translocation by the twin-arginine translocation complex" NARROW [] +synonym: "twin-arginine translocation pathway" EXACT [] +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0043954 +name: cellular component maintenance +namespace: biological_process +alt_id: GO:0071956 +def: "The organization process that preserves a cellular component in a stable functional or structural state." [GOC:dph, GOC:jl, GOC:mah] +synonym: "cellular component maintenance at cellular level" EXACT [] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0043955 +name: 3-hydroxypropionyl-CoA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate." [GOC:jl, PMID:11821399] +comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399. +synonym: "3-hydroxy propionyl-CoA synthetase activity" EXACT [] +synonym: "acetyl-coenzyme A synthetase" BROAD [] +synonym: "acetyl-coenzyme A synthetase/GroES-like domain" NARROW [] +synonym: "AMP-dependent synthetase and ligase" BROAD [] +synonym: "AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase" BROAD [] +synonym: "enoyl-CoA hydratase/isomerase" BROAD [] +xref: EC:6.2.1.36 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0043956 +name: 3-hydroxypropionyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O." [GOC:jl, PMID:11821399] +comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399. +synonym: "3-hydroxy propionyl-CoA dehydratase activity" EXACT [] +synonym: "acetyl-coenzyme A synthetase" BROAD [] +synonym: "acetyl-coenzyme A synthetase/GroES-like domain" BROAD [] +synonym: "AMP-dependent synthetase and ligase" BROAD [] +synonym: "AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase" BROAD [] +synonym: "enoyl-CoA hydratase/isomerase" BROAD [] +xref: EC:4.2.1.116 +xref: MetaCyc:RXN-6383 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043957 +name: acryloyl-CoA reductase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+." [GOC:jl, PMID:11821399] +comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399. +synonym: "acetyl-coenzyme A synthetase" BROAD [] +synonym: "acetyl-coenzyme A synthetase/GroES-like domain" BROAD [] +synonym: "acryloyl-CoA reductase (NADPH) activity" EXACT [] +synonym: "acrylyl-CoA reductase (NADPH) activity" EXACT [] +synonym: "AMP-dependent synthetase and ligase" BROAD [] +synonym: "AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase" BROAD [] +synonym: "enoyl-CoA hydratase/isomerase" BROAD [] +xref: EC:1.3.1.84 +xref: KEGG_REACTION:R00919 +xref: MetaCyc:RXN-9087 +xref: RHEA:26456 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043958 +name: acryloyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein." [GOC:jl, PMID:12603323] +comment: Note that this function is part of the process of L-alanine fermentation to propionate. +synonym: "acryloyl-coenzyme A reductase activity" EXACT [] +synonym: "acrylyl-CoA reductase (NADH)" EXACT [] +synonym: "propionyl-CoA dehydrogenase" EXACT [] +xref: EC:1.3.99.3 +xref: MetaCyc:RXN-8568 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0043959 +name: L-erythro-3-methylmalyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA." [GOC:jl] +synonym: "HpcH/HpaI aldolase" RELATED [] +xref: EC:4.1.3.24 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0043960 +name: L-erythro-3-methylmalyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O." [GOC:jl] +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0043961 +name: succinyl-CoA:(R)-citramalate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA." [GOC:jl, PMID:17259315] +synonym: "L-carnitine dehydratase/bile acid-inducible protein F" RELATED [] +synonym: "succinyl-CoA:(R)-citramalate CoA transferase activity" EXACT [] +synonym: "succinyl-CoA:R-citramalate CoA transferase" EXACT [] +xref: EC:2.8.3.20 +xref: MetaCyc:RXN-8966 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0043962 +name: obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0043963 +name: modulation by symbiont of host adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0043964 +name: induction by symbiont of host adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "positive regulation by symbiont of host adenylate cyclase-mediated signal transduction" EXACT [] +is_a: GO:0043963 ! modulation by symbiont of host adenylate cyclase-mediated signal transduction +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway + +[Term] +id: GO:0043965 +name: suppression by symbiont of host adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "negative regulation by symbiont of host adenylate cyclase-mediated signal transduction" EXACT [] +is_a: GO:0043963 ! modulation by symbiont of host adenylate cyclase-mediated signal transduction +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway + +[Term] +id: GO:0043966 +name: histone H3 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group." [GOC:jl] +is_a: GO:0016573 ! histone acetylation + +[Term] +id: GO:0043967 +name: histone H4 acetylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an acetyl group." [GOC:jl] +is_a: GO:0016573 ! histone acetylation + +[Term] +id: GO:0043968 +name: histone H2A acetylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an acetyl group." [GOC:jl] +is_a: GO:0016573 ! histone acetylation + +[Term] +id: GO:0043969 +name: histone H2B acetylation +namespace: biological_process +def: "The modification of histone H2B by the addition of an acetyl group." [GOC:jl] +is_a: GO:0016573 ! histone acetylation + +[Term] +id: GO:0043970 +name: histone H3-K9 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K9" EXACT [] +synonym: "histone H3K9 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation +is_a: GO:0061647 ! histone H3-K9 modification + +[Term] +id: GO:0043971 +name: histone H3-K18 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K18" EXACT [] +synonym: "histone H3K18 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043972 +name: histone H3-K23 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K23" EXACT [] +synonym: "histone H3K23 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043973 +name: histone H3-K4 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K4" EXACT [] +synonym: "histone H3K4 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043974 +name: histone H3-K27 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K27" EXACT [] +synonym: "histone H3K27 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043975 +name: histone H3-K36 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K36" EXACT [] +synonym: "histone H3K36 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043976 +name: histone H3-K79 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone." [GOC:jl] +synonym: "histone H3 acetylation at K79" EXACT [] +synonym: "histone H3K79 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation + +[Term] +id: GO:0043977 +name: histone H2A-K5 acetylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone." [GOC:jl] +synonym: "histone H2A acetylation at K5" EXACT [] +is_a: GO:0043968 ! histone H2A acetylation + +[Term] +id: GO:0043978 +name: histone H2A-K9 acetylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone." [GOC:jl] +synonym: "histone H2A acetylation at K9" EXACT [] +is_a: GO:0043968 ! histone H2A acetylation + +[Term] +id: GO:0043979 +name: histone H2B-K5 acetylation +namespace: biological_process +def: "The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone." [GOC:jl] +synonym: "histone H2B acetylation at K5" EXACT [] +is_a: GO:0043969 ! histone H2B acetylation + +[Term] +id: GO:0043980 +name: histone H2B-K12 acetylation +namespace: biological_process +def: "The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone." [GOC:jl] +synonym: "histone H2B acetylation at K12" EXACT [] +is_a: GO:0043969 ! histone H2B acetylation + +[Term] +id: GO:0043981 +name: histone H4-K5 acetylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone." [GOC:jl] +synonym: "histone H4 acetylation at K5" EXACT [] +is_a: GO:0043967 ! histone H4 acetylation + +[Term] +id: GO:0043982 +name: histone H4-K8 acetylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone." [GOC:jl] +synonym: "histone H4 acetylation at K8" EXACT [] +is_a: GO:0043967 ! histone H4 acetylation + +[Term] +id: GO:0043983 +name: histone H4-K12 acetylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone." [GOC:jl] +synonym: "histone H4 acetylation at K12" EXACT [] +is_a: GO:0043967 ! histone H4 acetylation + +[Term] +id: GO:0043984 +name: histone H4-K16 acetylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone." [GOC:jl] +synonym: "histone H4 acetylation at K16" EXACT [] +is_a: GO:0043967 ! histone H4 acetylation + +[Term] +id: GO:0043985 +name: histone H4-R3 methylation +namespace: biological_process +def: "The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone." [GOC:mah] +synonym: "histone H4 methylation at R3" EXACT [] +synonym: "histone H4 R3 methylation" EXACT [] +synonym: "histone H4R3me" EXACT [] +is_a: GO:0034969 ! histone arginine methylation + +[Term] +id: GO:0043987 +name: histone H3-S10 phosphorylation +namespace: biological_process +alt_id: GO:0043986 +def: "The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone." [GOC:jl] +synonym: "histone H3 phosphorylation at S10" EXACT [] +synonym: "histone H3S10 phosphorylation" EXACT [] +is_a: GO:0035404 ! histone-serine phosphorylation + +[Term] +id: GO:0043988 +name: histone H3-S28 phosphorylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone." [GOC:jl] +synonym: "histone H3 phosphorylation at S28" EXACT [] +synonym: "histone H3S28 phosphorylation" EXACT [] +is_a: GO:0035404 ! histone-serine phosphorylation + +[Term] +id: GO:0043989 +name: histone H4-S1 phosphorylation +namespace: biological_process +def: "The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone." [GOC:jl] +synonym: "histone H4 phosphorylation at S1" EXACT [] +synonym: "histone H4S1 phosphorylation" EXACT [] +is_a: GO:0035404 ! histone-serine phosphorylation + +[Term] +id: GO:0043990 +name: histone H2A-S1 phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone." [GOC:jl] +synonym: "histone H2A phosphorylation at S1" EXACT [] +synonym: "histone H2AS1 phosphorylation" EXACT [] +is_a: GO:0035404 ! histone-serine phosphorylation +is_a: GO:1990164 ! histone H2A phosphorylation + +[Term] +id: GO:0043991 +name: histone H2B-S14 phosphorylation +namespace: biological_process +def: "The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone." [GOC:jl] +synonym: "histone H2B phosphorylation at S14" EXACT [] +synonym: "histone H2BS14 phosphorylation" EXACT [] +is_a: GO:0035404 ! histone-serine phosphorylation + +[Term] +id: GO:0043992 +name: histone acetyltransferase activity (H3-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K9 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043970 ! histone H3-K9 acetylation + +[Term] +id: GO:0043993 +name: histone acetyltransferase activity (H3-K18 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K18 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043971 ! histone H3-K18 acetylation + +[Term] +id: GO:0043994 +name: histone acetyltransferase activity (H3-K23 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K23 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043972 ! histone H3-K23 acetylation + +[Term] +id: GO:0043995 +name: histone acetyltransferase activity (H4-K5 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H4-K5 specific)" EXACT [] +is_a: GO:0010485 ! H4 histone acetyltransferase activity +relationship: part_of GO:0043981 ! histone H4-K5 acetylation + +[Term] +id: GO:0043996 +name: histone acetyltransferase activity (H4-K8 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H4-K8 specific)" EXACT [] +is_a: GO:0010485 ! H4 histone acetyltransferase activity +relationship: part_of GO:0043982 ! histone H4-K8 acetylation + +[Term] +id: GO:0043997 +name: histone acetyltransferase activity (H4-K12 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H4-K12 specific)" EXACT [] +is_a: GO:0010485 ! H4 histone acetyltransferase activity +relationship: part_of GO:0043983 ! histone H4-K12 acetylation + +[Term] +id: GO:0043998 +name: H2A histone acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine." [EC:2.3.1.48] +synonym: "H2A histone lysine N-acetyltransferase activity" EXACT [] +is_a: GO:0004402 ! histone acetyltransferase activity +relationship: part_of GO:0043968 ! histone H2A acetylation + +[Term] +id: GO:0043999 +name: histone acetyltransferase activity (H2A-K5 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H2A-K5 specific)" EXACT [] +is_a: GO:0043998 ! H2A histone acetyltransferase activity +relationship: part_of GO:0043977 ! histone H2A-K5 acetylation + +[Term] +id: GO:0044000 +name: movement in host +namespace: biological_process +def: "The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "movement of symbiont in host" EXACT [] +synonym: "movement of symbiont within host" EXACT [] +synonym: "movement within host" EXACT [] +synonym: "symbiont movement in host" EXACT [] +synonym: "symbiont movement within host" RELATED [] +is_a: GO:0052126 ! movement in host environment + +[Term] +id: GO:0044001 +name: migration in host +namespace: biological_process +def: "The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "migration within host" EXACT [] +is_a: GO:0044000 ! movement in host + +[Term] +id: GO:0044002 +name: acquisition of nutrients from host +namespace: biological_process +def: "The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc, GOC:jl] +is_a: GO:0051701 ! interaction with host +is_a: GO:0051816 ! acquisition of nutrients from other organism during symbiotic interaction + +[Term] +id: GO:0044003 +name: modulation by symbiont of host process +namespace: biological_process +alt_id: GO:0044004 +alt_id: GO:0044055 +def: "The process in which a symbiont organism effects a change in the structure or processes of its host organism." [GOC:cc] +synonym: "disruption by symbiont of host cell" RELATED [] +synonym: "modification by symbiont of host biological process" RELATED [] +synonym: "modification by symbiont of host morphology or physiology" RELATED [] +synonym: "modulation by symbiont of host system process" NARROW [] +synonym: "regulation by symbiont of host system process" NARROW [] +is_a: GO:0051701 ! interaction with host +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18719 xsd:anyURI + +[Term] +id: GO:0044007 +name: obsolete dissemination or transmission of symbiont from host +namespace: biological_process +def: "OBSOLETE. The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont. +synonym: "dissemination or transmission of organism from host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044008 +name: obsolete dissemination or transmission of symbiont from host by vector +namespace: biological_process +def: "OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont. +synonym: "dissemination or transmission of organism from host by vector" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044009 +name: obsolete viral transmission by vector +namespace: biological_process +def: "OBSOLETE. The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection." [GOC:cc] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus. +is_obsolete: true + +[Term] +id: GO:0044010 +name: single-species biofilm formation +namespace: biological_process +alt_id: GO:0052000 +def: "A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:cc, GOC:di, GOC:tb] +synonym: "auto-aggregation" BROAD [] +synonym: "bfp-dependent aggregation" NARROW [] +synonym: "bundle-forming fimbriae-dependent aggregation" NARROW [] +synonym: "bundle-forming pili-dependent aggregation" NARROW [] +synonym: "tfp-dependent aggregation" NARROW [] +synonym: "type IV pili-dependent aggregation" NARROW [] +is_a: GO:0042710 ! biofilm formation +is_a: GO:0051703 ! intraspecies interaction between organisms +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18814 xsd:anyURI + +[Term] +id: GO:0044011 +name: single-species biofilm formation on inanimate substrate +namespace: biological_process +def: "A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription." [GOC:cc] +is_a: GO:0090609 ! single-species submerged biofilm formation + +[Term] +id: GO:0044012 +name: histone acetyltransferase activity (H2A-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H2A-K9 specific)" EXACT [] +is_a: GO:0043998 ! H2A histone acetyltransferase activity +relationship: part_of GO:0043978 ! histone H2A-K9 acetylation + +[Term] +id: GO:0044013 +name: H2B histone acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine." [EC:2.3.1.48] +synonym: "H2B histone lysine N-acetyltransferase activity" EXACT [] +is_a: GO:0004402 ! histone acetyltransferase activity +relationship: part_of GO:0043969 ! histone H2B acetylation + +[Term] +id: GO:0044014 +name: histone acetyltransferase activity (H2B-K5 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H2B-K5 specific)" EXACT [] +is_a: GO:0044013 ! H2B histone acetyltransferase activity +relationship: part_of GO:0043979 ! histone H2B-K5 acetylation + +[Term] +id: GO:0044015 +name: histone acetyltransferase activity (H2B-K12 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H2B-K12 specific)" EXACT [] +is_a: GO:0044013 ! H2B histone acetyltransferase activity +relationship: part_of GO:0043980 ! histone H2B-K12 acetylation + +[Term] +id: GO:0044016 +name: histone acetyltransferase activity (H3-K4 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K4 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043973 ! histone H3-K4 acetylation + +[Term] +id: GO:0044017 +name: histone acetyltransferase activity (H3-K27 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K27 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043974 ! histone H3-K27 acetylation + +[Term] +id: GO:0044018 +name: histone acetyltransferase activity (H3-K36 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K36 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity +relationship: part_of GO:0043975 ! histone H3-K36 acetylation + +[Term] +id: GO:0044019 +name: histone acetyltransferase activity (H3-K72 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72)." [EC:2.3.1.48] +synonym: "histone lysine N-acetyltransferase activity (H3-K72 specific)" EXACT [] +is_a: GO:0010484 ! H3 histone acetyltransferase activity + +[Term] +id: GO:0044020 +name: histone methyltransferase activity (H4-R3 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4." [GOC:mah, PMID:17898714] +synonym: "histone methylase activity (H4-R3 specific)" EXACT [GOC:mah] +synonym: "histone-arginine N-methyltransferase activity (H4-R3 specific)" EXACT [] +is_a: GO:0008469 ! histone-arginine N-methyltransferase activity +relationship: part_of GO:0043985 ! histone H4-R3 methylation + +[Term] +id: GO:0044022 +name: histone kinase activity (H3-S28 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3." [GOC:jl] +synonym: "histone serine kinase activity (H3-S28 specific)" EXACT [] +synonym: "histone-serine kinase activity (H3-S28 specific)" EXACT [] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0043988 ! histone H3-S28 phosphorylation + +[Term] +id: GO:0044023 +name: histone kinase activity (H4-S1 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4." [GOC:jl] +synonym: "histone serine kinase activity (H4-S1 specific)" EXACT [] +synonym: "histone-serine kinase activity (H4-S1 specific)" EXACT [] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0043989 ! histone H4-S1 phosphorylation + +[Term] +id: GO:0044024 +name: histone kinase activity (H2A-S1 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A." [GOC:jl] +synonym: "histone serine kinase activity (H2A-S1 specific)" EXACT [] +synonym: "histone-serine kinase activity (H2A-S1 specific)" EXACT [] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0043990 ! histone H2A-S1 phosphorylation + +[Term] +id: GO:0044025 +name: histone kinase activity (H2B-S14 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B." [GOC:jl] +synonym: "histone serine kinase activity (H2B-S14 specific)" EXACT [] +synonym: "histone-serine kinase activity (H2B-S14 specific)" EXACT [] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0043991 ! histone H2B-S14 phosphorylation + +[Term] +id: GO:0044026 +name: DNA hypermethylation +namespace: biological_process +def: "An increase in the epigenetic methylation of cytosine and adenosine residues in DNA." [GOC:jl, http://en.wiktionary.org/] +is_a: GO:0044030 ! regulation of DNA methylation + +[Term] +id: GO:0044027 +name: hypermethylation of CpG island +namespace: biological_process +def: "An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes." [GOC:jl, Wikipedia:Cpg_island] +synonym: "DNA hypermethylation of CpG island" EXACT [] +is_a: GO:0044026 ! DNA hypermethylation + +[Term] +id: GO:0044028 +name: DNA hypomethylation +namespace: biological_process +def: "An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA." [GOC:jl, http://en.wiktionary.org/hypomethylation] +is_a: GO:0044030 ! regulation of DNA methylation + +[Term] +id: GO:0044029 +name: hypomethylation of CpG island +namespace: biological_process +def: "An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes." [GOC:jl, Wikipedia:Cpg_island] +synonym: "DNA hypomethylation of CpG island" EXACT [] +is_a: GO:0044028 ! DNA hypomethylation + +[Term] +id: GO:0044030 +name: regulation of DNA methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine." [GOC:jl] +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006306 ! DNA methylation +relationship: regulates GO:0006306 ! DNA methylation + +[Term] +id: GO:0044031 +name: modification by symbiont of host protein by phosphorylation +namespace: biological_process +def: "The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is intended for use in annotation of symbiont gene products. For host gene products that phosphorylate host proteins, consider annotation to 'protein amino acid phosphorylation ; GO:0006468'. Consider also annotation to the molecular function term 'protein kinase activity ; GO:0004672'. +is_a: GO:0075345 ! modification by symbiont of host protein + +[Term] +id: GO:0044032 +name: modulation by symbiont of indole acetic acid levels in host +namespace: biological_process +def: "The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate indole acetic acid levels in the host, consider annotating to 'auxin homeostasis ; GO:0010252'. +synonym: "modulation by symbiont of auxin levels in host" BROAD [] +synonym: "modulation by symbiont of IAA levels in host" EXACT [] +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0044033 +name: multi-organism metabolic process +namespace: biological_process +def: "A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism." [GOC:jl] +synonym: "multi-organism metabolism" EXACT [] +synonym: "multi-organismal metabolic process" EXACT [] +synonym: "multi-organismal metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process +is_a: GO:0051704 ! multi-organism process + +[Term] +id: GO:0044034 +name: obsolete multi-organism biosynthetic process +namespace: biological_process +def: "OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism." [GOC:jl] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "multi-organism biosynthesis" EXACT [] +synonym: "multi-organismal biosynthesis" EXACT [] +synonym: "multi-organismal biosynthetic process" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18787 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0044035 +name: multi-organism catabolic process +namespace: biological_process +def: "A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism." [GOC:jl] +synonym: "multi-organism catabolism" EXACT [] +synonym: "multi-organismal catabolic process" EXACT [] +synonym: "multi-organismal catabolism" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0044033 ! multi-organism metabolic process + +[Term] +id: GO:0044036 +name: cell wall macromolecule metabolic process +namespace: biological_process +alt_id: GO:0010382 +def: "The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:jl, GOC:mah] +synonym: "cellular cell wall macromolecule metabolic process" EXACT [] +synonym: "cellular cell wall macromolecule metabolism" EXACT [] +is_a: GO:0044260 ! cellular macromolecule metabolic process +relationship: part_of GO:0071554 ! cell wall organization or biogenesis + +[Term] +id: GO:0044037 +name: multi-organism cell wall macromolecule metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:mah, GOC:tair_curators] +synonym: "multi-organism cell wall macromolecule metabolism" EXACT [GOC:mah] +is_a: GO:0044033 ! multi-organism metabolic process +is_a: GO:0044036 ! cell wall macromolecule metabolic process +is_a: GO:0044764 ! multi-organism cellular process + +[Term] +id: GO:0044038 +name: cell wall macromolecule biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall." [GOC:go_curators] +synonym: "cell wall macromolecule anabolism" EXACT [GOC:mah] +synonym: "cell wall macromolecule biosynthesis" EXACT [GOC:mah] +synonym: "cell wall macromolecule biosynthetic process at cellular level" EXACT [GOC:mah] +synonym: "cell wall macromolecule synthesis" EXACT [GOC:mah] +synonym: "cellular cell wall macromolecule biosynthetic process" EXACT [GOC:mah] +is_a: GO:0044036 ! cell wall macromolecule metabolic process +is_a: GO:0070589 ! cellular component macromolecule biosynthetic process +relationship: part_of GO:0042546 ! cell wall biogenesis + +[Term] +id: GO:0044040 +name: multi-organism carbohydrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism." [GOC:jl] +synonym: "main pathways of carbohydrate metabolic process" NARROW [] +synonym: "main pathways of carbohydrate metabolism" NARROW [] +synonym: "multi-organism carbohydrate metabolism" EXACT [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:0044033 ! multi-organism metabolic process + +[Term] +id: GO:0044041 +name: multi-organism carbohydrate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism." [GOC:jl] +synonym: "multi-organism carbohydrate breakdown" EXACT [] +synonym: "multi-organism carbohydrate catabolism" EXACT [] +synonym: "multi-organism carbohydrate degradation" EXACT [] +is_a: GO:0016052 ! carbohydrate catabolic process +is_a: GO:0044035 ! multi-organism catabolic process +is_a: GO:0044040 ! multi-organism carbohydrate metabolic process + +[Term] +id: GO:0044042 +name: glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] +synonym: "glucan metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process + +[Term] +id: GO:0044043 +name: multi-organism glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism." [ISBN:0198547684] +synonym: "multi-organism glucan metabolism" EXACT [] +is_a: GO:0044040 ! multi-organism carbohydrate metabolic process +is_a: GO:0044042 ! glucan metabolic process + +[Term] +id: GO:0044044 +name: obsolete interaction with host via substance in symbiont surface +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process. +is_obsolete: true + +[Term] +id: GO:0044045 +name: obsolete interaction with host via substance in symbiont cell outer membrane +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process. +is_obsolete: true + +[Term] +id: GO:0044046 +name: obsolete interaction with host via substance released outside of symbiont +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis." [MITRE:tk] +comment: This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process. +synonym: "interaction with host via substance released outside of symbiont cells" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044047 +name: obsolete interaction with host via protein secreted by type I secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0044048 +name: obsolete interaction with host via protein secreted by type V secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0044049 +name: obsolete interaction with host via protein secreted by type VI secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0044050 +name: obsolete interaction with host via substance released by sporangium lysis +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process. +synonym: "interaction with host via substance released by lysis of symbiont sporangium" RELATED [] +synonym: "interaction with host via substance released by sporangia lysis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044051 +name: obsolete interaction with host via substance released by symbiont cytolysis +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [MITRE:tk] +comment: This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process. +synonym: "interaction with host via substance released by cytolysis of symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044052 +name: obsolete interaction with host via substance released by membrane budding +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle." [MITRE:tk] +comment: This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process. +synonym: "interaction with host via substance released by symbiont membrane budding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044053 +name: translocation of peptides or proteins into host cell cytoplasm +namespace: biological_process +def: "The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm." [MITRE:tk] +synonym: "translocation of symbiont peptides or proteins into host cell cytoplasm" EXACT [] +synonym: "transport of peptides or proteins into host cell cytoplasm" EXACT [] +is_a: GO:0042000 ! translocation of peptides or proteins into host + +[Term] +id: GO:0044056 +name: modulation by symbiont of host digestive system process +namespace: biological_process +def: "The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [MITRE:tk] +synonym: "regulation by symbiont of host digestive system process" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0044058 ! regulation of digestive system process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0022600 ! digestive system process + +[Term] +id: GO:0044057 +name: regulation of system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003008 ! system process +relationship: regulates GO:0003008 ! system process + +[Term] +id: GO:0044058 +name: regulation of digestive system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022600 ! digestive system process +relationship: regulates GO:0022600 ! digestive system process + +[Term] +id: GO:0044059 +name: modulation by symbiont of host endocrine process +namespace: biological_process +def: "The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism." [MITRE:tk] +synonym: "regulation by symbiont of host endocrine process" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0044060 ! regulation of endocrine process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0050886 ! endocrine process + +[Term] +id: GO:0044060 +name: regulation of endocrine process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl] +synonym: "regulation of endocrine system process" EXACT [] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050886 ! endocrine process +relationship: regulates GO:0050886 ! endocrine process + +[Term] +id: GO:0044061 +name: modulation by symbiont of host excretion +namespace: biological_process +def: "The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity." [MITRE:tk] +synonym: "regulation by symbiont of host excretion" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0044062 ! regulation of excretion + +[Term] +id: GO:0044062 +name: regulation of excretion +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl] +is_a: GO:0044057 ! regulation of system process +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007588 ! excretion +relationship: regulates GO:0007588 ! excretion + +[Term] +id: GO:0044063 +name: modulation by symbiont of host nervous system process +namespace: biological_process +def: "The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system." [MITRE:tk] +synonym: "modulation by symbiont of host neurological system process" EXACT [] +synonym: "regulation by symbiont of host neurological system process" EXACT [] +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0044003 ! modulation by symbiont of host process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0050877 ! nervous system process + +[Term] +id: GO:0044064 +name: modulation by symbiont of host respiratory system process +namespace: biological_process +def: "The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [MITRE:tk] +synonym: "regulation by symbiont of host respiratory system process" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0044065 ! regulation of respiratory system process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0003016 ! respiratory system process + +[Term] +id: GO:0044065 +name: regulation of respiratory system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl] +is_a: GO:0043576 ! regulation of respiratory gaseous exchange +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003016 ! respiratory system process +relationship: regulates GO:0003016 ! respiratory system process + +[Term] +id: GO:0044066 +name: modification by symbiont of host cell nucleus +namespace: biological_process +def: "The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus." [MITRE:tk] +synonym: "modification by symbiont of host nucleus" EXACT [] +synonym: "modification of host cell nucleus by symbiont" EXACT [] +synonym: "modification of host nucleus by symbiont" EXACT [] +is_a: GO:0052043 ! modification by symbiont of host cellular component + +[Term] +id: GO:0044067 +name: modification by symbiont of host intercellular junctions +namespace: biological_process +def: "The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells." [MITRE:tk] +synonym: "modification of host intercellular junctions by symbiont" EXACT [] +is_a: GO:0052043 ! modification by symbiont of host cellular component + +[Term] +id: GO:0044068 +name: modulation by symbiont of host cellular process +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism." [MITRE:tk] +synonym: "modulation of host cellular process by symbiont" EXACT [] +synonym: "regulation by symbiont of host cellular process" EXACT [] +synonym: "regulation of host cellular process by symbiont" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0009987 ! cellular process + +[Term] +id: GO:0044069 +name: modulation by symbiont of host anion transport +namespace: biological_process +def: "The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism." [MITRE:tk] +synonym: "modification of host anion transport by symbiont" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: regulates GO:0006820 ! anion transport + +[Term] +id: GO:0044070 +name: regulation of anion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] +is_a: GO:0043269 ! regulation of ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006820 ! anion transport +relationship: regulates GO:0006820 ! anion transport + +[Term] +id: GO:0044071 +name: modulation by symbiont of host cell cycle +namespace: biological_process +def: "The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery." [MITRE:tk] +synonym: "modification by symbiont of host cell cycle" EXACT [] +synonym: "modulation of host cell cycle by symbiont" EXACT [] +synonym: "regulation by symbiont of host cell cycle" EXACT [] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0022402 ! cell cycle process + +[Term] +id: GO:0044072 +name: negative regulation by symbiont of host cell cycle +namespace: biological_process +def: "The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery." [MITRE:tk] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0044071 ! modulation by symbiont of host cell cycle +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: negatively_regulates GO:0022402 ! cell cycle process + +[Term] +id: GO:0044073 +name: modulation by symbiont of host translation +namespace: biological_process +def: "The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism." [MITRE:tk] +synonym: "modification by symbiont of host translation" EXACT [] +synonym: "modulation of host translation by symbiont" EXACT [] +synonym: "regulation by symbiont of host translation" EXACT [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0044068 ! modulation by symbiont of host cellular process + +[Term] +id: GO:0044074 +name: negative regulation by symbiont of host translation +namespace: biological_process +def: "The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism." [MITRE:tk] +synonym: "negative regulation of host translation by symbiont" EXACT [] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0044073 ! modulation by symbiont of host translation + +[Term] +id: GO:0044075 +name: modulation by symbiont of host vacuole organization +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism." [MITRE:tk] +synonym: "modulation by symbiont of host vacuole biogenesis" RELATED [GOC:mah] +synonym: "modulation by symbiont of host vacuole organisation" EXACT [GOC:mah] +synonym: "modulation of host vacuole organization by symbiont" EXACT [GOC:mah] +synonym: "regulation by symbiont of host vacuole organization" EXACT [GOC:mah] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0044088 ! regulation of vacuole organization + +[Term] +id: GO:0044076 +name: positive regulation by symbiont of host vacuole organization +namespace: biological_process +def: "The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism." [MITRE:tk] +synonym: "positive regulation by symbiont of host vacuole biogenesis" RELATED [GOC:mah] +synonym: "positive regulation by symbiont of host vacuole organisation" EXACT [GOC:mah] +synonym: "positive regulation of host vacuole organization by symbiont" EXACT [] +is_a: GO:0044075 ! modulation by symbiont of host vacuole organization +is_a: GO:0044090 ! positive regulation of vacuole organization + +[Term] +id: GO:0044077 +name: modulation by symbiont of host receptor-mediated endocytosis +namespace: biological_process +def: "The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism." [MITRE:tk] +synonym: "modulation of host receptor-mediated endocytosis by symbiont" EXACT [] +synonym: "regulation by symbiont of host receptor-mediated endocytosis" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis + +[Term] +id: GO:0044078 +name: positive regulation by symbiont of host receptor-mediated endocytosis +namespace: biological_process +def: "Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism." [MITRE:tk] +synonym: "positive regulation of host receptor-mediated endocytosis by symbiont" EXACT [] +is_a: GO:0044077 ! modulation by symbiont of host receptor-mediated endocytosis +is_a: GO:0048260 ! positive regulation of receptor-mediated endocytosis + +[Term] +id: GO:0044079 +name: modulation by symbiont of host neurotransmitter secretion +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism." [MITRE:tk] +synonym: "modification by symbiont of host neurotransmitter secretion" EXACT [] +synonym: "modulation of host neurotransmitter secretion by symbiont" EXACT [] +synonym: "regulation by symbiont of host neurotransmitter secretion" EXACT [] +is_a: GO:0044758 ! modulation by symbiont of host synaptic transmission +is_a: GO:0046928 ! regulation of neurotransmitter secretion +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0007269 ! neurotransmitter secretion + +[Term] +id: GO:0044080 +name: modulation by symbiont of host cGMP-mediated signal transduction +namespace: biological_process +def: "Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response." [MITRE:tk] +synonym: "modulation by symbiont of host cGMP-mediated signal transduction pathway" EXACT [] +synonym: "modulation by symbiont of host cGMP-mediated signaling" EXACT [] +synonym: "modulation by symbiont of host cGMP-mediated signalling" EXACT [] +synonym: "modulation of host cGMP-mediated signal transduction by symbiont" EXACT [] +synonym: "regulation by symbiont of host cGMP-mediated signal transduction" EXACT [] +is_a: GO:0010752 ! regulation of cGMP-mediated signaling +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0044081 +name: modulation by symbiont of host nitric oxide-mediated signal transduction +namespace: biological_process +def: "Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO)." [MITRE:tk] +synonym: "modulation by symbiont of host nitric oxide mediated signal transduction" EXACT [] +synonym: "modulation of host nitric oxide-mediated signal transduction by symbiont" EXACT [] +synonym: "modulation of host nitric oxide-mediated signaling by symbiont" EXACT [] +synonym: "modulation of host nitric oxide-mediated signalling by symbiont" EXACT [] +synonym: "regulation by symbiont of host nitric oxide-mediated signal transduction" EXACT [] +is_a: GO:0010749 ! regulation of nitric oxide mediated signal transduction +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0044082 +name: modulation by symbiont of host small GTPase mediated signal transduction +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism." [MITRE:tk] +synonym: "modulation of host small GTPase mediated signal transduction by symbiont" EXACT [] +synonym: "regulation by symbiont of host small GTPase mediated signal transduction" EXACT [] +is_a: GO:0051056 ! regulation of small GTPase mediated signal transduction +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0044083 +name: modulation by symbiont of host Rho protein signal transduction +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism." [MITRE:tk] +synonym: "modulation by symbiont of host Rho protein mediated signal transduction" EXACT [] +synonym: "modulation by symbiont of host Rho protein-mediated signal transduction" EXACT [] +synonym: "modulation of host Rho protein signal transduction by symbiont" EXACT [] +synonym: "modulation of host Rho protein signaling by symbiont" EXACT [] +synonym: "modulation of host Rho protein signalling by symbiont" EXACT [] +synonym: "regulation by symbiont of host Rho protein signal transduction" EXACT [] +is_a: GO:0035023 ! regulation of Rho protein signal transduction +is_a: GO:0044082 ! modulation by symbiont of host small GTPase mediated signal transduction + +[Term] +id: GO:0044084 +name: host cell membrane pore complex +namespace: cellular_component +def: "Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins." [MITRE:tk] +synonym: "pore complex in host cell membrane" EXACT [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0033644 ! host cell membrane + +[Term] +id: GO:0044085 +name: cellular component biogenesis +namespace: biological_process +alt_id: GO:0071843 +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "cellular component biogenesis at cellular level" EXACT [] +is_a: GO:0071840 ! cellular component organization or biogenesis + +[Term] +id: GO:0044087 +name: regulation of cellular component biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044085 ! cellular component biogenesis +relationship: regulates GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0044088 +name: regulation of vacuole organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] +synonym: "regulation of vacuole biogenesis" RELATED [GOC:mah] +synonym: "regulation of vacuole organisation" EXACT [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007033 ! vacuole organization +relationship: regulates GO:0007033 ! vacuole organization + +[Term] +id: GO:0044089 +name: positive regulation of cellular component biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044085 ! cellular component biogenesis +relationship: positively_regulates GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0044090 +name: positive regulation of vacuole organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] +synonym: "positive regulation of vacuole biogenesis" RELATED [GOC:mah] +synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0044088 ! regulation of vacuole organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007033 ! vacuole organization +relationship: positively_regulates GO:0007033 ! vacuole organization + +[Term] +id: GO:0044091 +name: membrane biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl] +is_a: GO:0044085 ! cellular component biogenesis + +[Term] +id: GO:0044092 +name: negative regulation of molecular function +namespace: biological_process +def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003674 ! molecular_function +relationship: negatively_regulates GO:0003674 ! molecular_function +created_by: jl +creation_date: 2009-04-21T04:07:27Z + +[Term] +id: GO:0044093 +name: positive regulation of molecular function +namespace: biological_process +def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003674 ! molecular_function +relationship: positively_regulates GO:0003674 ! molecular_function +created_by: jl +creation_date: 2009-04-21T04:11:06Z + +[Term] +id: GO:0044094 +name: host cell nuclear part +namespace: cellular_component +def: "Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction." [GOC:ecd] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_a: GO:0033646 ! host intracellular part +relationship: part_of GO:0042025 ! host cell nucleus +created_by: jl +creation_date: 2009-04-22T01:59:14Z + +[Term] +id: GO:0044095 +name: host cell nucleoplasm +namespace: cellular_component +def: "That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction." [GOC:ecd] +is_a: GO:0044094 ! host cell nuclear part +created_by: jl +creation_date: 2009-04-22T02:02:51Z + +[Term] +id: GO:0044096 +name: type IV pilus +namespace: cellular_component +def: "A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers." [GOC:pamgo_curators] +synonym: "TFP" EXACT [] +synonym: "type 4 pilus" EXACT [] +synonym: "type IV fimbriae" EXACT [] +is_a: GO:0009289 ! pilus +created_by: jl +creation_date: 2009-04-22T02:52:55Z + +[Term] +id: GO:0044097 +name: secretion by the type IV secretion system +namespace: biological_process +def: "The controlled release of proteins or DNA by a cell, via the type IV secretion system." [GOC:pamgo_curators] +synonym: "secretion via the type IV secretion system" EXACT [] +is_a: GO:0032940 ! secretion by cell +created_by: jl +creation_date: 2009-06-09T02:20:34Z + +[Term] +id: GO:0044098 +name: DNA secretion by the type IV secretion system +namespace: biological_process +def: "The controlled release of DNA by a cell, via the type IV secretion system." [GOC:pamgo_curators] +synonym: "DNA secretion via the type IV secretion system" EXACT [] +is_a: GO:0044097 ! secretion by the type IV secretion system +created_by: jl +creation_date: 2009-06-09T02:26:57Z + +[Term] +id: GO:0044099 +name: polar tube +namespace: cellular_component +def: "A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell." [GOC:mf, PMID:12076771, PMID:9723921] +is_a: GO:0110165 ! cellular anatomical entity +created_by: jl +creation_date: 2009-06-09T03:12:32Z + +[Term] +id: GO:0044100 +name: sporoplasm +namespace: cellular_component +def: "The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms." [GOC:mf, PMID:12076771, PMID:16004371, PMID:9723921] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular +created_by: jl +creation_date: 2009-06-09T03:27:03Z + +[Term] +id: GO:0044101 +name: (R)-citramalyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA." [GOC:jl] +synonym: "Ccl" RELATED [] +synonym: "R-citramalyl-CoA lyase activity" EXACT [] +xref: EC:4.1.3.46 +xref: MetaCyc:RXN-8967 +is_a: GO:0016833 ! oxo-acid-lyase activity +created_by: jl +creation_date: 2009-07-09T03:14:15Z + +[Term] +id: GO:0044102 +name: purine deoxyribosyltransferase activity +namespace: molecular_function +def: "Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor." [GOC:jl, PMID:11836245] +synonym: "PTD" RELATED [] +synonym: "purine 2'-deoxyribosyltransferase activity" EXACT [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +created_by: jl +creation_date: 2009-07-09T03:40:15Z + +[Term] +id: GO:0044103 +name: L-arabinose 1-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+." [GOC:jl, PMID:16326697] +xref: EC:1.1.1.376 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: jl +creation_date: 2009-07-09T04:00:30Z + +[Term] +id: GO:0044104 +name: 2,5-dioxovalerate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+." [PMID:16835232, PMID:17202142] +synonym: "2,5-dioxopentanoate dehydrogenase (NAD+) activity" EXACT [] +synonym: "2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity" EXACT [] +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor +created_by: jl +creation_date: 2009-07-09T04:15:14Z + +[Term] +id: GO:0044105 +name: L-xylulose reductase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+." [PMID:14736891] +xref: EC:1.1.1.10 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: jl +creation_date: 2009-07-09T04:25:43Z + +[Term] +id: GO:0044106 +name: cellular amine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +created_by: jl +creation_date: 2009-07-15T11:55:44Z + +[Term] +id: GO:0044107 +name: cellular alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells." [GOC:jl] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0044237 ! cellular metabolic process +created_by: jl +creation_date: 2009-07-15T01:36:19Z + +[Term] +id: GO:0044108 +name: cellular alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell." [GOC:jl] +is_a: GO:0044107 ! cellular alcohol metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0046165 ! alcohol biosynthetic process +created_by: jl +creation_date: 2009-07-15T01:38:25Z + +[Term] +id: GO:0044109 +name: cellular alcohol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell." [GOC:jl] +is_a: GO:0044107 ! cellular alcohol metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0046164 ! alcohol catabolic process +created_by: jl +creation_date: 2009-07-15T01:44:27Z + +[Term] +id: GO:0044110 +name: growth involved in symbiotic interaction +namespace: biological_process +alt_id: GO:0044153 +def: "The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction." [GO:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development during symbiotic interaction ; GO:0052171'. See also 'development during symbiotic interaction ; GO:0044111'. +synonym: "growth during symbiotic interaction" RELATED [GOC:dph] +synonym: "growth on or near surface of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "growth on or near surface of other organism involved in symbiotic interaction" RELATED [] +is_a: GO:0040007 ! growth +is_a: GO:0044419 ! interspecies interaction between organisms +created_by: jl +creation_date: 2009-07-30T02:22:33Z + +[Term] +id: GO:0044111 +name: development involved in symbiotic interaction +namespace: biological_process +alt_id: GO:0044152 +def: "The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction." [GO:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development during symbiotic interaction ; GO:0052171'. See also 'growth during symbiotic interaction ; GO:0044110'. +synonym: "development during symbiotic interaction" RELATED [gOC:dph] +synonym: "development on or near surface of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "development on or near surface of other organism involved in symbiotic interaction" NARROW [] +is_a: GO:0032502 ! developmental process +is_a: GO:0051704 ! multi-organism process +intersection_of: GO:0032502 ! developmental process +intersection_of: part_of GO:0044419 ! interspecies interaction between organisms +relationship: part_of GO:0044419 ! interspecies interaction between organisms +created_by: jl +creation_date: 2009-07-30T02:26:46Z + +[Term] +id: GO:0044113 +name: development in other organism involved in symbiotic interaction +namespace: biological_process +def: "The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism." [GO:jl, GOC:cc] +comment: This term partially replaces the obsolete term 'growth or development in other organism during symbiotic interaction ; GO:0051831'. See also 'growth in other organism during symbiotic interaction ; GO:0044112'. +synonym: "development in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044111 ! development involved in symbiotic interaction +created_by: jl +creation_date: 2009-07-30T02:32:38Z + +[Term] +id: GO:0044114 +name: development of symbiont in host +namespace: biological_process +alt_id: GO:0044122 +alt_id: GO:0044124 +def: "The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host ; GO:0044412'. See also 'growth of symbiont in host ; GO:0044117'. +synonym: "development of symbiont in host intercellular space" NARROW [] +synonym: "development of symbiont in host vascular tissue" NARROW [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +created_by: jl +creation_date: 2009-07-30T03:39:25Z + +[Term] +id: GO:0044115 +name: development of symbiont involved in interaction with host +namespace: biological_process +def: "The progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont during interaction with host ; GO:0052108'. See also 'growth of symbiont in host ; GO:0044117'. +synonym: "development of symbiont during interaction with host" RELATED [GOC:dph] +is_a: GO:0044111 ! development involved in symbiotic interaction +created_by: jl +creation_date: 2009-07-30T03:26:36Z + +[Term] +id: GO:0044117 +name: growth of symbiont in host +namespace: biological_process +alt_id: GO:0044112 +alt_id: GO:0044116 +alt_id: GO:0044123 +alt_id: GO:0044125 +def: "The increase in size or mass of an organism, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host ; GO:0044412'. See also 'development of symbiont in host ; GO:0044114'. +synonym: "growth in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "growth in other organism involved in symbiotic interaction" RELATED [] +synonym: "growth of symbiont during interaction with host" RELATED [GOC:tb] +synonym: "growth of symbiont in host intercellular space" BROAD [] +synonym: "growth of symbiont in host vascular tissue" NARROW [] +synonym: "growth of symbiont involved in interaction with host" RELATED [] +is_a: GO:0044110 ! growth involved in symbiotic interaction +is_a: GO:0044403 ! symbiotic process +created_by: jl +creation_date: 2009-07-30T02:32:14Z + +[Term] +id: GO:0044118 +name: development of symbiont in host cell +namespace: biological_process +def: "The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host cell ; GO:0075065'. See also 'growth of symbiont in host cell ; GO:0044119'. +is_a: GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2009-07-30T03:52:00Z + +[Term] +id: GO:0044119 +name: growth of symbiont in host cell +namespace: biological_process +def: "The increase in size or mass of symbiont, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host cell ; GO:0075065'. See also 'development of symbiont in host cell ; GO:0044118'. This term refers to an increase in mass of a symbiont in a host cell; it should not be used to annotate an increase in number of symbionts, e.g. viral replication in a host cell. +is_a: GO:0044117 ! growth of symbiont in host +created_by: jl +creation_date: 2009-07-30T03:52:30Z + +[Term] +id: GO:0044120 +name: development of symbiont in host vacuole +namespace: biological_process +def: "The progression of the symbiont from an initial condition to a later condition, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host organelle ; GO:0075066'. See also 'growth of symbiont in host organelle ; GO:0044121'. +synonym: "development of symbiont in host organelle" BROAD [] +is_a: GO:0044118 ! development of symbiont in host cell +created_by: jl +creation_date: 2009-07-30T03:59:54Z + +[Term] +id: GO:0044121 +name: growth of symbiont in host vacuole +namespace: biological_process +def: "The increase in size or mass of a symbiont, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont in host organelle ; GO:0075066'. See also 'development of symbiont in host organelle ; GO:0044120'. +synonym: "growth of symbiont in host organelle" BROAD [] +is_a: GO:0044119 ! growth of symbiont in host cell +created_by: jl +creation_date: 2009-07-30T04:00:25Z + +[Term] +id: GO:0044126 +name: obsolete regulation of growth of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T02:10:08Z + +[Term] +id: GO:0044127 +name: regulation of development of symbiont in host +namespace: biological_process +def: "Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'regulation of growth or development of symbiont in host ; GO:0033665'. See also 'regulation of growth of symbiont in host ; GO:0044126'. +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044114 ! development of symbiont in host +relationship: regulates GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2009-08-04T02:11:08Z + +[Term] +id: GO:0044128 +name: obsolete positive regulation of growth of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T02:20:57Z + +[Term] +id: GO:0044129 +name: positive regulation of development of symbiont in host +namespace: biological_process +def: "Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont in host ; GO:0033666'. See also 'positive regulation of growth of symbiont in host ; GO:0044128'. +is_a: GO:0044127 ! regulation of development of symbiont in host +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044114 ! development of symbiont in host +relationship: positively_regulates GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2009-08-04T02:25:41Z + +[Term] +id: GO:0044130 +name: obsolete negative regulation of growth of symbiont in host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T02:42:25Z + +[Term] +id: GO:0044131 +name: negative regulation of development of symbiont in host +namespace: biological_process +def: "Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont in host ; GO:0033667'. See also 'negative regulation of growth of symbiont in host ; GO:0044130'. +is_a: GO:0044127 ! regulation of development of symbiont in host +is_a: GO:0044147 ! negative regulation of development of symbiont involved in interaction with host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044114 ! development of symbiont in host +relationship: negatively_regulates GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2009-08-04T02:42:56Z + +[Term] +id: GO:0044132 +name: development of symbiont on or near host +namespace: biological_process +def: "The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism." [GOC:jl, GOC:pamgo_curators] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +created_by: jl +creation_date: 2009-08-04T03:36:02Z + +[Term] +id: GO:0044133 +name: growth of symbiont on or near host +namespace: biological_process +def: "The increase in size or mass of a symbiont within the cells or tissues of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'growth or development of symbiont on or near host ; GO:0044408'. See also 'development of symbiont on or near host ; GO:0044132'. +is_a: GO:0044110 ! growth involved in symbiotic interaction +created_by: jl +creation_date: 2009-08-04T03:36:49Z + +[Term] +id: GO:0044134 +name: development of symbiont on or near host phyllosphere +namespace: biological_process +def: "The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +is_a: GO:0044132 ! development of symbiont on or near host +created_by: jl +creation_date: 2009-08-04T04:10:58Z + +[Term] +id: GO:0044135 +name: obsolete growth of symbiont on or near host phyllosphere +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18786 xsd:anyURI +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T04:11:23Z + +[Term] +id: GO:0044136 +name: development of symbiont on or near host rhizosphere +namespace: biological_process +def: "The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +is_a: GO:0044132 ! development of symbiont on or near host +created_by: jl +creation_date: 2009-08-04T04:18:35Z + +[Term] +id: GO:0044137 +name: obsolete growth of symbiont on or near host rhizosphere +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18786 xsd:anyURI +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T04:19:07Z + +[Term] +id: GO:0044138 +name: modulation of development of symbiont on or near host +namespace: biological_process +def: "Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'modulation of growth or development of symbiont on or near host ; GO:0075305'. See also 'modulation of growth of symbiont on or near host ; GO:0044139'. +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +relationship: regulates GO:0044132 ! development of symbiont on or near host +created_by: jl +creation_date: 2009-08-04T04:24:25Z + +[Term] +id: GO:0044139 +name: obsolete modulation of growth of symbiont on or near host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T04:24:59Z + +[Term] +id: GO:0044140 +name: obsolete negative regulation of growth of symbiont on or near host surface +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-04T04:31:26Z + +[Term] +id: GO:0044141 +name: negative regulation of development of symbiont on or near host surface +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont on or near host surface ; GO:0075309'. See also 'negative regulation of growth of symbiont on or near host surface ; GO:0044140'. +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0044147 ! negative regulation of development of symbiont involved in interaction with host +relationship: negatively_regulates GO:0044132 ! development of symbiont on or near host +created_by: jl +creation_date: 2009-08-04T04:32:18Z + +[Term] +id: GO:0044142 +name: obsolete positive regulation of growth of symbiont on or near host surface +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +is_obsolete: true +created_by: jl +creation_date: 2009-08-06T01:35:18Z + +[Term] +id: GO:0044143 +name: positive regulation of development of symbiont on or near host surface +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont on or near host surface ; GO:0075337'. See also 'positive regulation of growth of symbiont on or near host surface ; GO:0044142'. +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +relationship: positively_regulates GO:0044132 ! development of symbiont on or near host +created_by: jl +creation_date: 2009-08-06T01:35:48Z + +[Term] +id: GO:0044144 +name: obsolete modulation of growth of symbiont involved in interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +synonym: "modulation of growth of symbiont during interaction with host" RELATED [GOC:tb] +is_obsolete: true +created_by: jl +creation_date: 2009-08-06T01:56:48Z + +[Term] +id: GO:0044145 +name: modulation of development of symbiont involved in interaction with host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'modulation of growth or development of symbiont during interaction with host ; GO:0075338'. See also 'modulation of growth of symbiont during interaction with host ; GO:0044144'. +synonym: "modulation of development of symbiont during interaction with host" RELATED [GOC:dph] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0050793 ! regulation of developmental process +relationship: regulates GO:0044115 ! development of symbiont involved in interaction with host +created_by: jl +creation_date: 2009-08-06T01:57:38Z + +[Term] +id: GO:0044146 +name: obsolete negative regulation of growth of symbiont involved in interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +synonym: "negative regulation of growth of symbiont during interaction with host" RELATED [GOC:tb] +is_obsolete: true +created_by: jl +creation_date: 2009-08-06T02:04:24Z + +[Term] +id: GO:0044147 +name: negative regulation of development of symbiont involved in interaction with host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont during interaction with host ; GO:0075340'. +synonym: "negative regulation of development of symbiont during interaction with host" RELATED [GOC:dph] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044115 ! development of symbiont involved in interaction with host +relationship: negatively_regulates GO:0044115 ! development of symbiont involved in interaction with host +created_by: jl +creation_date: 2009-08-06T02:04:59Z + +[Term] +id: GO:0044148 +name: obsolete positive regulation of growth of symbiont involved in interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent. +synonym: "positive regulation of growth of symbiont during interaction with host" RELATED [GOC:tb] +is_obsolete: true +created_by: jl +creation_date: 2009-08-06T02:20:27Z + +[Term] +id: GO:0044149 +name: positive regulation of development of symbiont involved in interaction with host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl, GOC:pamgo_curators] +comment: This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont during interaction with host ; GO:0075339'. See also 'positive regulation of growth of symbiont during interaction with host ; GO:0044148'. +synonym: "positive regulation of development of symbiont during interaction with host" RELATED [GOC:dph] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044115 ! development of symbiont involved in interaction with host +relationship: positively_regulates GO:0044115 ! development of symbiont involved in interaction with host +created_by: jl +creation_date: 2009-08-06T02:20:55Z + +[Term] +id: GO:0044150 +name: development of host on or near symbiont surface +namespace: biological_process +def: "The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc, GOC:jl] +synonym: "development of organism on or near symbiont surface" EXACT [] +is_a: GO:0044111 ! development involved in symbiotic interaction +created_by: jl +creation_date: 2009-08-06T03:15:52Z + +[Term] +id: GO:0044151 +name: obsolete growth of host on or near symbiont surface +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc, GOC:jl] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "growth of organism on or near symbiont surface" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18786 xsd:anyURI +is_obsolete: true +created_by: jl +creation_date: 2009-08-06T03:16:19Z + +[Term] +id: GO:0044154 +name: histone H3-K14 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone." [GOC:jl, GOC:lb, PMID:17194708] +synonym: "histone H3 acetylation at K14" EXACT [] +synonym: "histone H3K14 acetylation" EXACT [] +is_a: GO:0043966 ! histone H3 acetylation +created_by: jl +creation_date: 2009-08-11T03:40:43Z + +[Term] +id: GO:0044155 +name: host caveola +namespace: cellular_component +def: "A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:rph] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0033644 ! host cell membrane +created_by: jl +creation_date: 2009-08-11T04:00:55Z + +[Term] +id: GO:0044156 +name: host cell junction +namespace: cellular_component +def: "A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix." [GOC:rph] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0020002 ! host cell plasma membrane +created_by: jl +creation_date: 2009-08-11T04:04:50Z + +[Term] +id: GO:0044157 +name: host cell projection +namespace: cellular_component +def: "A prolongation or process extending from a host cell, e.g. a flagellum or axon." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-08-11T04:07:24Z + +[Term] +id: GO:0044158 +name: host cell wall +namespace: cellular_component +def: "The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-08-11T04:09:23Z + +[Term] +id: GO:0044159 +name: host thylakoid +namespace: cellular_component +def: "A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation." [GOC:rph] +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-08-11T04:15:34Z + +[Term] +id: GO:0044160 +name: host thylakoid membrane +namespace: cellular_component +def: "The pigmented membrane of any host thylakoid." [GOC:rph] +is_a: GO:0033644 ! host cell membrane +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0044159 ! host thylakoid +created_by: jl +creation_date: 2009-08-11T04:17:31Z + +[Term] +id: GO:0044161 +name: host cell cytoplasmic vesicle +namespace: cellular_component +def: "A vesicle formed of membrane or protein, found in the cytoplasm of a host cell." [GOC:rph] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-08-11T04:22:21Z + +[Term] +id: GO:0044162 +name: host cell cytoplasmic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a host cell cytoplasmic vesicle." [GOC:rph] +is_a: GO:0033644 ! host cell membrane +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0044161 ! host cell cytoplasmic vesicle +created_by: jl +creation_date: 2009-08-11T04:24:02Z + +[Term] +id: GO:0044163 +name: host cytoskeleton +namespace: cellular_component +def: "Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:rph] +is_a: GO:0033647 ! host intracellular organelle +created_by: jl +creation_date: 2009-08-11T04:27:04Z + +[Term] +id: GO:0044164 +name: host cell cytosol +namespace: cellular_component +def: "The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:jl] +synonym: "host cytosol" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-09-04T11:03:27Z + +[Term] +id: GO:0044165 +name: host cell endoplasmic reticulum +namespace: cellular_component +def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." [GOC:jl] +synonym: "host endoplasmic reticulum" EXACT [] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-09-04T11:08:09Z + +[Term] +id: GO:0044166 +name: host cell endoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the host cell endoplasmic reticulum." [GOC:jl] +synonym: "host endoplasmic reticulum lumen" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0044165 ! host cell endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:13:30Z + +[Term] +id: GO:0044167 +name: host cell endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the host cell endoplasmic reticulum." [GOC:jl] +synonym: "host endoplasmic reticulum membrane" EXACT [] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0033645 ! host cell endomembrane system +relationship: part_of GO:0044165 ! host cell endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:19:23Z + +[Term] +id: GO:0044168 +name: host cell rough endoplasmic reticulum +namespace: cellular_component +def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface." [GOC:jl] +synonym: "host rough endoplasmic reticulum" EXACT [] +is_a: GO:0044165 ! host cell endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:23:28Z + +[Term] +id: GO:0044169 +name: host cell rough endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the host cell rough endoplasmic reticulum." [GOC:jl] +synonym: "host rough endoplasmic reticulum membrane" EXACT [] +is_a: GO:0044167 ! host cell endoplasmic reticulum membrane +relationship: part_of GO:0044168 ! host cell rough endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:30:38Z + +[Term] +id: GO:0044170 +name: host cell smooth endoplasmic reticulum +namespace: cellular_component +def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface." [GOC:jl] +synonym: "host smooth endoplasmic reticulum" EXACT [] +is_a: GO:0044165 ! host cell endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:33:29Z + +[Term] +id: GO:0044171 +name: host cell smooth endoplasmic reticulum membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the host cell smooth endoplasmic reticulum." [GOC:jl] +synonym: "host smooth endoplasmic reticulum membrane" EXACT [] +is_a: GO:0044167 ! host cell endoplasmic reticulum membrane +relationship: part_of GO:0044170 ! host cell smooth endoplasmic reticulum +created_by: jl +creation_date: 2009-09-04T11:46:00Z + +[Term] +id: GO:0044172 +name: host cell endoplasmic reticulum-Golgi intermediate compartment +namespace: cellular_component +def: "A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport." [GOC:jl, GOC:pr] +synonym: "host cell ER-Golgi intermediate compartment" EXACT [] +synonym: "host ER-Golgi intermediate compartment" EXACT [] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-09-04T02:44:07Z + +[Term] +id: GO:0044173 +name: host cell endoplasmic reticulum-Golgi intermediate compartment membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system." [GOC:jl] +synonym: "host cell ER-Golgi intermediate compartment membrane" EXACT [] +synonym: "host endoplasmic reticulum-Golgi intermediate compartment membrane" EXACT [] +synonym: "host ER-Golgi intermediate compartment membrane" EXACT [] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0044172 ! host cell endoplasmic reticulum-Golgi intermediate compartment +created_by: jl +creation_date: 2009-09-04T02:46:13Z + +[Term] +id: GO:0044174 +name: host cell endosome +namespace: cellular_component +def: "A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation." [GOC:jl] +synonym: "host endosome" EXACT [] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-09-04T03:02:01Z + +[Term] +id: GO:0044175 +name: host cell endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a host cell endosome." [GOC:jl] +synonym: "host endosome membrane" EXACT [] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0044174 ! host cell endosome +created_by: jl +creation_date: 2009-09-04T03:04:04Z + +[Term] +id: GO:0044176 +name: host cell filopodium +namespace: cellular_component +def: "Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward." [GOC:jl] +synonym: "host filopodium" EXACT [] +is_a: GO:0044157 ! host cell projection +created_by: jl +creation_date: 2009-09-04T03:06:59Z + +[Term] +id: GO:0044177 +name: host cell Golgi apparatus +namespace: cellular_component +def: "A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack." [GOC:jl] +synonym: "host Golgi apparatus" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-09-04T03:14:38Z + +[Term] +id: GO:0044178 +name: host cell Golgi membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus." [GOC:jl] +synonym: "host Golgi membrane" EXACT [] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0033645 ! host cell endomembrane system +relationship: part_of GO:0044177 ! host cell Golgi apparatus +created_by: jl +creation_date: 2009-09-04T03:16:14Z + +[Term] +id: GO:0044179 +name: hemolysis in other organism +namespace: biological_process +def: "The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another." [GOC:jl] +subset: goslim_chembl +synonym: "hemolysis of cells in other organism" EXACT [GOC:bf] +synonym: "hemolysis of erythrocytes in other organism" EXACT [] +synonym: "hemolysis of RBCs in other organism" EXACT [] +synonym: "hemolysis of red blood cells in other organism" EXACT [] +is_a: GO:0051715 ! cytolysis in other organism +created_by: jl +creation_date: 2009-09-04T03:36:00Z + +[Term] +id: GO:0044180 +name: filamentous growth of a unicellular organism +namespace: biological_process +def: "The process in which a unicellular organism grows in a threadlike, filamentous shape." [GOC:mtg_cambridge_2009] +is_a: GO:0030447 ! filamentous growth +created_by: jl +creation_date: 2009-09-25T10:16:01Z + +[Term] +id: GO:0044181 +name: filamentous growth of a multicellular organism +namespace: biological_process +def: "The process in which a multicellular organism grows in a threadlike, filamentous shape." [GOC:mtg_cambridge_2009] +is_a: GO:0030447 ! filamentous growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +created_by: jl +creation_date: 2009-09-25T10:17:58Z + +[Term] +id: GO:0044182 +name: filamentous growth of a population of unicellular organisms +namespace: biological_process +def: "The process in which a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:mtg_cambridge_2009] +is_a: GO:0030447 ! filamentous growth +created_by: jl +creation_date: 2009-09-25T10:18:32Z + +[Term] +id: GO:0044183 +name: protein folding chaperone +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding." [GOC:mtg_cambridge_2009] +subset: goslim_chembl +synonym: "chaperone activity" BROAD [] +synonym: "protein binding involved in protein folding" EXACT [] +is_a: GO:0003674 ! molecular_function +intersection_of: GO:0003674 ! molecular_function +intersection_of: has_part GO:0005515 ! protein binding +intersection_of: part_of GO:0006457 ! protein folding +relationship: has_part GO:0005515 ! protein binding +relationship: part_of GO:0006457 ! protein folding +created_by: jl +creation_date: 2009-09-25T11:33:48Z + +[Term] +id: GO:0044184 +name: host cell late endosome +namespace: cellular_component +def: "A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." [GOC:jl] +is_a: GO:0044174 ! host cell endosome +created_by: jl +creation_date: 2009-10-15T02:58:34Z + +[Term] +id: GO:0044185 +name: host cell late endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a host cell late endosome." [GOC:jl] +is_a: GO:0044175 ! host cell endosome membrane +relationship: part_of GO:0044184 ! host cell late endosome +created_by: jl +creation_date: 2009-10-15T03:00:39Z + +[Term] +id: GO:0044186 +name: host cell lipid droplet +namespace: cellular_component +def: "Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins." [GOC:jl] +synonym: "host cell lipid adiposome" EXACT [] +synonym: "host cell lipid body" EXACT [] +synonym: "host cell lipid particle" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-10-15T03:05:06Z + +[Term] +id: GO:0044187 +name: host cell lysosome +namespace: cellular_component +def: "A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions." [GOC:jl] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-10-15T03:26:00Z + +[Term] +id: GO:0044188 +name: host cell lysosomal membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm." [GOC:jl] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0044187 ! host cell lysosome +created_by: jl +creation_date: 2009-10-15T03:27:54Z + +[Term] +id: GO:0044189 +name: obsolete host cell microsome +namespace: cellular_component +def: "OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic host cells are homogenized and that sediment on centrifugation at 100000 g." [GOC:jl] +comment: This term was obsoleted because it refers to a cell fractionation experimental result and not a bona fide cellular component. +synonym: "host cell microsomal membrane" EXACT [] +synonym: "host cell microsome" EXACT [] +is_obsolete: true +consider: GO:0033648 +created_by: jl +creation_date: 2009-10-15T04:04:24Z + +[Term] +id: GO:0044190 +name: host cell mitochondrial envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space." [GOC:jl] +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0033650 ! host cell mitochondrion +created_by: jl +creation_date: 2009-10-15T04:12:55Z + +[Term] +id: GO:0044191 +name: host cell mitochondrial membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope." [GOC:jl] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0044190 ! host cell mitochondrial envelope +created_by: jl +creation_date: 2009-10-15T04:14:35Z + +[Term] +id: GO:0044192 +name: host cell mitochondrial inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae." [GOC:jl] +is_a: GO:0044191 ! host cell mitochondrial membrane +created_by: jl +creation_date: 2009-10-15T04:17:29Z + +[Term] +id: GO:0044193 +name: host cell mitochondrial outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope." [GOC:jl] +is_a: GO:0039661 ! host organelle outer membrane +is_a: GO:0044191 ! host cell mitochondrial membrane +created_by: jl +creation_date: 2009-10-15T04:18:44Z + +[Term] +id: GO:0044194 +name: cytolytic granule +namespace: cellular_component +def: "A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells." [GOC:jl, PMID:11052265, PMID:12766758] +is_a: GO:0005764 ! lysosome +created_by: jl +creation_date: 2009-10-20T01:22:13Z + +[Term] +id: GO:0044195 +name: nucleoplasmic reticulum +namespace: cellular_component +def: "Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport." [GOC:jl, PMID:17959832, PMID:9024685] +synonym: "nuclear channels" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005635 ! nuclear envelope +created_by: jl +creation_date: 2009-10-20T02:24:09Z + +[Term] +id: GO:0044196 +name: host cell nucleolus +namespace: cellular_component +def: "A small, dense body one or more of which are present in the nucleus of eukaryotic host cells." [GOC:jl] +is_a: GO:0044094 ! host cell nuclear part +created_by: jl +creation_date: 2009-10-20T02:37:07Z + +[Term] +id: GO:0044197 +name: Rel homology domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT." [InterPro:IPR011539, Wikipedia:Rel_homology_domain] +synonym: "RHD binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding +created_by: jl +creation_date: 2009-10-20T03:57:48Z + +[Term] +id: GO:0044198 +name: zf-TRAF domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a TRAF-type zinc finger domain of a protein." [InterPro:IPR001293] +synonym: "TRAF-type zinc finger domain binding" EXACT [] +synonym: "zinc finger TRAF-type domain binding" EXACT [] +synonym: "zinc-finger-TRAF domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding +created_by: jl +creation_date: 2009-10-20T04:09:08Z + +[Term] +id: GO:0044199 +name: host cell nuclear envelope +namespace: cellular_component +def: "The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [GOC:jl] +is_a: GO:0044094 ! host cell nuclear part +relationship: part_of GO:0033645 ! host cell endomembrane system +created_by: jl +creation_date: 2009-10-21T10:56:11Z + +[Term] +id: GO:0044200 +name: host cell nuclear membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:jl] +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0044199 ! host cell nuclear envelope +created_by: jl +creation_date: 2009-10-21T10:59:08Z + +[Term] +id: GO:0044201 +name: host cell nuclear inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope." [GOC:jl] +is_a: GO:0044200 ! host cell nuclear membrane +created_by: jl +creation_date: 2009-10-21T11:08:33Z + +[Term] +id: GO:0044202 +name: host cell nuclear outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes." [GOC:jl] +is_a: GO:0039661 ! host organelle outer membrane +is_a: GO:0044200 ! host cell nuclear membrane +created_by: jl +creation_date: 2009-10-21T11:10:23Z + +[Term] +id: GO:0044203 +name: host cell nuclear lamina +namespace: cellular_component +def: "The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments." [GOC:jl] +is_a: GO:0044094 ! host cell nuclear part +relationship: part_of GO:0044201 ! host cell nuclear inner membrane +created_by: jl +creation_date: 2009-10-21T11:11:56Z + +[Term] +id: GO:0044204 +name: host cell nuclear matrix +namespace: cellular_component +def: "The dense fibrillar network lying on the inner side of the host nuclear membrane." [GOC:jl] +is_a: GO:0044094 ! host cell nuclear part +created_by: jl +creation_date: 2009-10-21T11:15:36Z + +[Term] +id: GO:0044205 +name: 'de novo' UMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen." [GOC:ecd, GOC:jl] +synonym: "'de novo' UMP biosynthesis" EXACT [] +is_a: GO:0006222 ! UMP biosynthetic process +created_by: jl +creation_date: 2009-10-21T11:27:31Z + +[Term] +id: GO:0044206 +name: UMP salvage +namespace: biological_process +def: "Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis." [GOC:ecd, PMID:15096496] +synonym: "UMP biosynthesis via nucleoside salvage pathway" EXACT [] +synonym: "UMP biosynthetic process via nucleoside salvage pathway" EXACT [] +is_a: GO:0006222 ! UMP biosynthetic process +is_a: GO:0010138 ! pyrimidine ribonucleotide salvage +created_by: jl +creation_date: 2009-10-21T11:32:33Z + +[Term] +id: GO:0044207 +name: translation initiation ternary complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl] +synonym: "Met-tRNA/eIF2.GTP ternary complex" NARROW [] +synonym: "translation initiation (ternary) complex" EXACT [] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: jl +creation_date: 2009-10-22T02:38:55Z + +[Term] +id: GO:0044208 +name: 'de novo' AMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP)." [GOC:ecd, PMID:10888601] +is_a: GO:0006167 ! AMP biosynthetic process +created_by: jl +creation_date: 2009-10-22T02:48:30Z + +[Term] +id: GO:0044209 +name: AMP salvage +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis." [GOC:ecd, GOC:jl, PMID:8917457, PMID:9864350] +synonym: "adenosine monophosphate salvage" EXACT [] +synonym: "AMP biosynthetic process via salvage pathway" EXACT [] +is_a: GO:0006167 ! AMP biosynthetic process +is_a: GO:0032261 ! purine nucleotide salvage +created_by: jl +creation_date: 2009-10-22T02:52:11Z + +[Term] +id: GO:0044210 +name: 'de novo' CTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components." [GOC:ecd, GOC:jl, PMID:11912132, PMID:18439916] +synonym: "'de novo' cytidine 5'-triphosphate biosynthetic process" EXACT [] +is_a: GO:0006241 ! CTP biosynthetic process +created_by: jl +creation_date: 2009-10-22T03:22:34Z + +[Term] +id: GO:0044211 +name: CTP salvage +namespace: biological_process +def: "Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis." [GOC:ecd, GOC:jl, PMID:10501935] +synonym: "CTP biosynthetic process via salvage pathway" EXACT [] +synonym: "cytidine 5'-triphosphate salvage" EXACT [] +is_a: GO:0006241 ! CTP biosynthetic process +is_a: GO:0010138 ! pyrimidine ribonucleotide salvage +created_by: jl +creation_date: 2009-10-22T03:24:04Z + +[Term] +id: GO:0044214 +name: spanning component of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane." [GOC:ecd] +comment: Proteins that span the membrane but have the bulk on one side of the membrane may be additionally annotated with a term of the form integral to X side of the plasma membrane. +synonym: "fully spanning plasma membrane" EXACT [] +synonym: "transmembrane" RELATED [GOC:mah] +is_a: GO:0005887 ! integral component of plasma membrane +is_a: GO:0089717 ! spanning component of membrane +intersection_of: GO:0089717 ! spanning component of membrane +intersection_of: part_of GO:0005886 ! plasma membrane +created_by: jl +creation_date: 2009-11-04T01:50:57Z + +[Term] +id: GO:0044215 +name: obsolete other organism +namespace: cellular_component +def: "OBSOLETE. A secondary organism with which the first organism is interacting." [GOC:jl] +comment: This term was obsoleted because it represents an organism, which is outside the scope of GO. +is_obsolete: true +created_by: jl +creation_date: 2009-11-12T01:04:58Z + +[Term] +id: GO:0044216 +name: other organism cell +namespace: cellular_component +def: "A cell of a secondary organism with which the first organism is interacting." [GOC:jl] +is_a: GO:0044217 ! other organism part +created_by: jl +creation_date: 2009-11-12T01:17:06Z + +[Term] +id: GO:0044217 +name: other organism part +namespace: cellular_component +def: "Any constituent part of a secondary organism with which the first organism is interacting." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_a: GO:0005575 ! cellular_component +created_by: jl +creation_date: 2009-11-12T01:18:21Z + +[Term] +id: GO:0044218 +name: other organism cell membrane +namespace: cellular_component +alt_id: GO:0044279 +def: "The cell membrane of a secondary organism with which the first organism is interacting." [GOC:jl] +synonym: "foreign membrane" RELATED [] +synonym: "other organism membrane" BROAD [] +is_a: GO:0044217 ! other organism part +relationship: part_of GO:0044216 ! other organism cell +created_by: jl +creation_date: 2009-11-12T02:37:44Z + +[Term] +id: GO:0044219 +name: host cell plasmodesma +namespace: cellular_component +def: "A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell." [GOC:rph, PMID:16903353] +is_a: GO:0044156 ! host cell junction +created_by: jl +creation_date: 2009-11-12T02:50:52Z + +[Term] +id: GO:0044220 +name: host cell perinuclear region of cytoplasm +namespace: cellular_component +def: "The host cell cytoplasm situated near, or occurring around, the host nucleus." [GOC:rph] +is_a: GO:0033655 ! host cell cytoplasm part +created_by: jl +creation_date: 2009-11-12T02:58:13Z + +[Term] +id: GO:0044221 +name: host cell synapse +namespace: cellular_component +def: "The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-11-12T03:03:59Z + +[Term] +id: GO:0044222 +name: anammoxosome +namespace: cellular_component +def: "An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism." [GOC:dh, PMID:17993524, PMID:19682260] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +created_by: jl +creation_date: 2009-11-12T04:03:24Z + +[Term] +id: GO:0044223 +name: pirellulosome +namespace: cellular_component +def: "A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm." [GOC:dh, PMID:19133117] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +created_by: jl +creation_date: 2009-11-12T04:08:07Z + +[Term] +id: GO:0044224 +name: juxtaparanode region of axon +namespace: cellular_component +def: "A region of an axon near a node of Ranvier that is between the paranode and internode regions." [GOC:BHF, GOC:jl, PMID:10624965, PMID:14682359] +synonym: "juxta paranode axon" RELATED [NIF_Subcellular:sao1191319089] +synonym: "juxtaparanodal region" EXACT [] +synonym: "juxtaparanode" EXACT [] +xref: NIF_Subcellular:sao758620702 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044304 ! main axon +created_by: jl +creation_date: 2009-11-13T12:57:36Z + +[Term] +id: GO:0044225 +name: apical pole of neuron +namespace: cellular_component +def: "Portion of a neuron cell soma closest to the point where the apical dendrite emerges." [NIF_Subcellular:sao1186862860] +xref: NIF_Subcellular:sao1186862860 +is_a: GO:0060187 ! cell pole +relationship: part_of GO:0043025 ! neuronal cell body +created_by: jl +creation_date: 2009-11-13T03:49:14Z + +[Term] +id: GO:0044226 +name: basal pole of neuron +namespace: cellular_component +def: "Portion of a neuron cell soma closest to the point where the basilar dendrite emerges." [NIF_Subcellular:sao1186862860] +xref: NIF_Subcellular:sao1186862860 +is_a: GO:0060187 ! cell pole +relationship: part_of GO:0043025 ! neuronal cell body +created_by: jl +creation_date: 2009-11-13T04:32:17Z + +[Term] +id: GO:0044227 +name: methane-oxidizing organelle +namespace: cellular_component +def: "A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms." [GOC:dh] +synonym: "methane-oxidizing compartment" EXACT [] +synonym: "methanotroph intracytoplasmic membrane-bound compartment" EXACT [] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +created_by: jl +creation_date: 2009-11-17T02:13:52Z + +[Term] +id: GO:0044228 +name: host cell surface +namespace: cellular_component +def: "The external part of the host cell wall and/or host plasma membrane." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-12-03T01:49:45Z + +[Term] +id: GO:0044229 +name: host cell periplasmic space +namespace: cellular_component +def: "The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi)." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-12-03T01:52:31Z + +[Term] +id: GO:0044230 +name: host cell envelope +namespace: cellular_component +def: "An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present." [GOC:rph] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2009-12-03T03:24:03Z + +[Term] +id: GO:0044231 +name: host cell presynaptic membrane +namespace: cellular_component +alt_id: GO:0072556 +def: "A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane." [GOC:rph] +synonym: "host cell pre-synaptic membrane" EXACT [] +synonym: "other organism pre-synaptic membrane" RELATED [] +synonym: "other organism presynaptic membrane" RELATED [] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0033644 ! host cell membrane +relationship: part_of GO:0044221 ! host cell synapse +created_by: jl +creation_date: 2009-12-08T02:11:18Z + +[Term] +id: GO:0044232 +name: organelle membrane contact site +namespace: cellular_component +def: "A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions." [GOC:jl, PMID:16806880] +synonym: "inter-organelle junction" NARROW [] +synonym: "interorganelle junction" NARROW [] +synonym: "MCS" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043226 ! organelle +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18994 xsd:anyURI +created_by: jl +creation_date: 2010-01-07T03:44:20Z + +[Term] +id: GO:0044233 +name: mitochondria-associated endoplasmic reticulum membrane +namespace: cellular_component +def: "A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange." [GOC:jl, PMID:19556461, PMID:22078959, PMID:29626751, PMID:29684109] +synonym: "endoplasmic reticulum-mitochondrion membrane contact site" EXACT [] +synonym: "ER-mitochondrion membrane contact site" EXACT [] +synonym: "MAM" RELATED [] +synonym: "mitochondria-associated ER membrane" EXACT [] +synonym: "Mitochondria-associated Membrane" RELATED [] +synonym: "mitochondria-associated membrane" EXACT [] +synonym: "mitochondria-endoplasmic reticulum (ER) contact" EXACT [PMID:29870872] +is_a: GO:0044232 ! organelle membrane contact site +created_by: jl +creation_date: 2010-01-07T04:07:24Z + +[Term] +id: GO:0044237 +name: cellular metabolic process +namespace: biological_process +def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] +synonym: "cellular metabolism" EXACT [] +synonym: "intermediary metabolism" RELATED [GOC:mah] +is_a: GO:0008152 ! metabolic process +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0044238 +name: primary metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: goslim_pir +synonym: "primary metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0044239 +name: obsolete salivary polysaccharide catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth." [GOC:jl, http://www.emc.maricopa.edu/] +comment: The reason for obsoletion is that this term represents the location of a process, which should be captured by the relation 'occurs in'. +synonym: "salivary polysaccharide breakdown" EXACT [] +synonym: "salivary polysaccharide catabolism" EXACT [] +synonym: "salivary polysaccharide degradation" EXACT [] +is_obsolete: true +consider: GO:0000272 + +[Term] +id: GO:0044241 +name: lipid digestion +namespace: biological_process +def: "The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism." [GOC:go_curators] +is_a: GO:0007586 ! digestion + +[Term] +id: GO:0044242 +name: cellular lipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells." [GOC:jl] +synonym: "cellular lipid breakdown" EXACT [] +synonym: "cellular lipid catabolism" EXACT [] +synonym: "cellular lipid degradation" EXACT [] +is_a: GO:0016042 ! lipid catabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0044245 +name: polysaccharide digestion +namespace: biological_process +def: "The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism." [GOC:go_curators] +is_a: GO:0007586 ! digestion + +[Term] +id: GO:0044247 +name: cellular polysaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells." [GOC:jl] +synonym: "cellular polysaccharide breakdown" EXACT [] +synonym: "cellular polysaccharide catabolism" EXACT [] +synonym: "cellular polysaccharide degradation" EXACT [] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process + +[Term] +id: GO:0044248 +name: cellular catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl] +synonym: "cellular breakdown" EXACT [] +synonym: "cellular catabolism" EXACT [] +synonym: "cellular degradation" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0044249 +name: cellular biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] +synonym: "cellular anabolism" EXACT [] +synonym: "cellular biosynthesis" EXACT [] +synonym: "cellular formation" EXACT [] +synonym: "cellular synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0044250 +name: negative regulation of metabolic activity involved in hibernation +namespace: biological_process +def: "The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation." [GOC:jl, Wikipedia:Hibernation] +synonym: "down regulation of metabolic activity during hibernation" RELATED [] +synonym: "down-regulation of metabolic activity during hibernation" RELATED [] +synonym: "downregulation of metabolic activity during hibernation" RELATED [] +synonym: "inhibition of metabolic activity during hibernation" NARROW [] +synonym: "negative regulation of metabolic activity during hibernation" RELATED [GOC:tb] +is_a: GO:0009892 ! negative regulation of metabolic process +relationship: part_of GO:0042750 ! hibernation + +[Term] +id: GO:0044251 +name: obsolete protein catabolic process by pepsin +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid)." [GOC:jl, http://www.emc.maricopa.edu/] +comment: The reason for obsoletion is that this term represents a specific gene product. +synonym: "protein breakdown by pepsin" EXACT [] +synonym: "protein degradation by pepsin" EXACT [] +is_obsolete: true +consider: GO:0030163 + +[Term] +id: GO:0044255 +name: cellular lipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipids, as carried out by individual cells." [GOC:jl] +subset: goslim_pir +synonym: "cellular lipid metabolism" EXACT [] +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0044256 +name: protein digestion +namespace: biological_process +def: "The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism." [GOC:go_curators] +is_a: GO:0007586 ! digestion + +[Term] +id: GO:0044257 +name: cellular protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:jl] +synonym: "cellular protein breakdown" EXACT [] +synonym: "cellular protein catabolism" EXACT [] +synonym: "cellular protein degradation" EXACT [] +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0044265 ! cellular macromolecule catabolic process +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0044258 +name: intestinal lipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, http://www.emc.maricopa.edu/] +synonym: "intestinal lipid breakdown" EXACT [] +synonym: "intestinal lipid catabolism" EXACT [] +synonym: "intestinal lipid degradation" EXACT [] +is_a: GO:0016042 ! lipid catabolic process + +[Term] +id: GO:0044260 +name: cellular macromolecule metabolic process +namespace: biological_process +alt_id: GO:0034960 +def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." [GOC:mah] +synonym: "cellular biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "cellular macromolecule metabolism" EXACT [] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0044262 +name: cellular carbohydrate metabolic process +namespace: biological_process +alt_id: GO:0006092 +def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:jl] +synonym: "cellular carbohydrate metabolism" EXACT [] +synonym: "main pathways of carbohydrate metabolic process" NARROW [] +synonym: "main pathways of carbohydrate metabolism" NARROW [] +is_a: GO:0005975 ! carbohydrate metabolic process +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0044264 +name: cellular polysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells." [GOC:jl] +synonym: "cellular glycan metabolic process" EXACT [] +synonym: "cellular glycan metabolism" EXACT [] +synonym: "cellular polysaccharide metabolism" EXACT [] +is_a: GO:0005976 ! polysaccharide metabolic process +is_a: GO:0044260 ! cellular macromolecule metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0044265 +name: cellular macromolecule catabolic process +namespace: biological_process +alt_id: GO:0034962 +def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." [GOC:jl] +synonym: "cellular biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] +synonym: "cellular macromolecule breakdown" EXACT [] +synonym: "cellular macromolecule catabolism" EXACT [] +synonym: "cellular macromolecule degradation" EXACT [] +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0044267 +name: cellular protein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification." [GOC:jl] +synonym: "cellular protein metabolism" EXACT [] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0044269 +name: glycerol ether catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol." [GOC:jl] +synonym: "glycerol ether breakdown" EXACT [] +synonym: "glycerol ether catabolism" EXACT [] +synonym: "glycerol ether degradation" EXACT [] +is_a: GO:0006662 ! glycerol ether metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0044270 +name: cellular nitrogen compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] +synonym: "nitrogen compound breakdown" BROAD [] +synonym: "nitrogen compound catabolism" BROAD [] +synonym: "nitrogen compound degradation" BROAD [] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0044271 +name: cellular nitrogen compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] +synonym: "nitrogen compound anabolism" BROAD [] +synonym: "nitrogen compound biosynthesis" BROAD [] +synonym: "nitrogen compound formation" BROAD [] +synonym: "nitrogen compound synthesis" BROAD [] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0044272 +name: sulfur compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] +synonym: "sulfur biosynthesis" NARROW [] +synonym: "sulfur biosynthetic process" NARROW [] +synonym: "sulfur compound anabolism" EXACT [] +synonym: "sulfur compound biosynthesis" EXACT [] +synonym: "sulfur compound formation" EXACT [] +synonym: "sulfur compound synthesis" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0044273 +name: sulfur compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] +synonym: "sulfur catabolic process" NARROW [] +synonym: "sulfur catabolism" NARROW [] +synonym: "sulfur compound breakdown" EXACT [] +synonym: "sulfur compound catabolism" EXACT [] +synonym: "sulfur compound degradation" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0044248 ! cellular catabolic process + +[Term] +id: GO:0044275 +name: cellular carbohydrate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells." [GOC:jl] +synonym: "cellular carbohydrate breakdown" EXACT [] +synonym: "cellular carbohydrate catabolism" EXACT [] +synonym: "cellular carbohydrate degradation" EXACT [] +is_a: GO:0016052 ! carbohydrate catabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0044277 +name: cell wall disassembly +namespace: biological_process +alt_id: GO:0060871 +def: "A process that results in the breakdown of the cell wall." [GOC:jl] +synonym: "cellular cell wall disassembly" EXACT [] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0071555 ! cell wall organization +created_by: jl +creation_date: 2010-01-14T02:00:34Z + +[Term] +id: GO:0044278 +name: cell wall disruption in other organism +namespace: biological_process +def: "A process carried out by an organism that results in the breakdown of the cell wall of a second organism." [GOC:jl] +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2010-01-14T02:01:48Z + +[Term] +id: GO:0044280 +name: subplasmalemmal coating +namespace: cellular_component +def: "Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier." [NIF_Subcellular:sao1938587839] +xref: NIF_Subcellular:sao1938587839 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031234 ! extrinsic component of cytoplasmic side of plasma membrane +created_by: jl +creation_date: 2010-01-14T03:58:38Z + +[Term] +id: GO:0044281 +name: small molecule metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] +comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_metagenomics +synonym: "small molecule metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process +created_by: jl +creation_date: 2010-01-26T12:05:20Z + +[Term] +id: GO:0044282 +name: small molecule catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw] +comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. +synonym: "small molecule catabolism" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0044281 ! small molecule metabolic process +created_by: jl +creation_date: 2010-01-26T12:06:10Z + +[Term] +id: GO:0044283 +name: small molecule biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] +comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. +synonym: "small molecule biosynthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0044281 ! small molecule metabolic process +created_by: jl +creation_date: 2010-01-26T12:06:49Z + +[Term] +id: GO:0044284 +name: mitochondrial crista junction +namespace: cellular_component +def: "A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane." [GOC:mcc, PMID:21944719, PMID:21987634, PMID:22009199] +synonym: "crista junction" EXACT [] +synonym: "cristae junction" EXACT [] +is_a: GO:0044232 ! organelle membrane contact site +relationship: part_of GO:0005743 ! mitochondrial inner membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18994 xsd:anyURI +created_by: jl +creation_date: 2010-02-02T10:07:39Z + +[Term] +id: GO:0044286 +name: peg and socket contact +namespace: cellular_component +def: "A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells." [GOC:tfm, NIF_Subcellular:sao1943947957, PMID:12883993, PMID:16166562, PMID:17591898] +synonym: "ball and socket contact" EXACT [GOC:tfm, PMID:17591898] +xref: NIF_Subcellular:sao1943947957 +is_a: GO:0044291 ! cell-cell contact zone +created_by: jl +creation_date: 2010-02-02T10:15:27Z + +[Term] +id: GO:0044288 +name: puncta adhaerentia +namespace: cellular_component +def: "A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells." [NIF_Subcellular:sao257629430] +xref: NIF_Subcellular:sao257629430 +is_a: GO:0005915 ! zonula adherens +created_by: jl +creation_date: 2010-02-04T02:19:38Z + +[Term] +id: GO:0044289 +name: mitochondrial inner-outer membrane contact site +namespace: cellular_component +alt_id: GO:0044285 +def: "Sites of close apposition of the inner and outer mitochondrial membrane." [PMID:22009199] +synonym: "bridge contact site" RELATED [] +synonym: "contact site" BROAD [] +is_a: GO:0044232 ! organelle membrane contact site +relationship: part_of GO:0031966 ! mitochondrial membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18994 xsd:anyURI +created_by: jl +creation_date: 2010-02-04T02:25:11Z + +[Term] +id: GO:0044290 +name: mitochondrial intracristal space +namespace: cellular_component +def: "The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space." [NIF_Subcellular:sao508958414] +xref: NIF_Subcellular:sao508958414 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005739 ! mitochondrion +created_by: jl +creation_date: 2010-02-04T02:32:10Z + +[Term] +id: GO:0044291 +name: cell-cell contact zone +namespace: cellular_component +def: "Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle." [NIF_Subcellular:sao1299635018] +synonym: "cell cell contact zone" EXACT [] +xref: NIF_Subcellular:sao1299635018 +is_a: GO:0005911 ! cell-cell junction +created_by: jl +creation_date: 2010-02-04T02:42:54Z + +[Term] +id: GO:0044292 +name: dendrite terminus +namespace: cellular_component +def: "A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole." [GOC:jl, NIF_Subcellular:sao28175134] +synonym: "dendrite terminal" EXACT [] +synonym: "dendrite terminal specialization" RELATED [] +synonym: "terminal specialization" RELATED [NIF_Subcellular:sao28175134] +synonym: "terminal specialization of a dendrite" EXACT [] +xref: NIF_Subcellular:sao28175134 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030425 ! dendrite +created_by: jl +creation_date: 2010-02-04T03:14:37Z + +[Term] +id: GO:0044293 +name: dendriole +namespace: cellular_component +def: "Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC)." [GOC:jl, NIF_Subcellular:sao28175134, NIF_Subcellular:sao295057932, PMID:8300904] +xref: NIF_Subcellular:sao28175134 +xref: NIF_Subcellular:sao295057932 +is_a: GO:0044292 ! dendrite terminus +created_by: jl +creation_date: 2010-02-04T03:32:02Z + +[Term] +id: GO:0044294 +name: dendritic growth cone +namespace: cellular_component +def: "The migrating motile tip of a growing nerve cell dendrite." [GOC:jl] +synonym: "dendrite growth cone" EXACT [] +xref: NIF_Subcellular:sao1594955670 +is_a: GO:0030426 ! growth cone +is_a: GO:0044292 ! dendrite terminus +created_by: jl +creation_date: 2010-02-04T03:45:27Z + +[Term] +id: GO:0044295 +name: axonal growth cone +namespace: cellular_component +def: "The migrating motile tip of a growing nerve cell axon." [GOC:jl, NIF_Subcellular:sao203987954] +synonym: "axon growth cone" EXACT [] +xref: NIF_Subcellular:sao1594955670 +xref: NIF_Subcellular:sao203987954 +is_a: GO:0030426 ! growth cone +created_by: jl +creation_date: 2010-02-04T03:57:16Z + +[Term] +id: GO:0044296 +name: dendritic tuft +namespace: cellular_component +def: "The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance." [NIF_Subcellular:sao1340260079] +synonym: "dendrite tuft" EXACT [] +xref: NIF_Subcellular:sao1340260079 +is_a: GO:0044292 ! dendrite terminus +created_by: jl +creation_date: 2010-02-04T04:03:29Z + +[Term] +id: GO:0044297 +name: cell body +namespace: cellular_component +def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] +comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. +synonym: "cell soma" EXACT [] +xref: FBbt:00005107 +xref: FMA:67301 +xref: Wikipedia:Cell_body +is_a: GO:0110165 ! cellular anatomical entity +created_by: jl +creation_date: 2010-02-05T10:37:16Z + +[Term] +id: GO:0044298 +name: cell body membrane +namespace: cellular_component +def: "The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections." [GOC:ecd] +synonym: "cell soma membrane" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0044297 ! cell body +created_by: jl +creation_date: 2010-02-05T10:39:23Z + +[Term] +id: GO:0044299 +name: C-fiber +namespace: cellular_component +def: "The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated." [NIF_Subcellular:nlx_subcell_20090210] +synonym: "C-fibre" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090210 +is_a: GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T11:14:51Z + +[Term] +id: GO:0044300 +name: cerebellar mossy fiber +namespace: cellular_component +def: "An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations." [NIF_Subcellular:nlx_subcell_20090209] +synonym: "cerebellar mossy fibre" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090209 +is_a: GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T11:16:40Z + +[Term] +id: GO:0044301 +name: climbing fiber +namespace: cellular_component +def: "The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber." [NIF_Subcellular:nlx_subcell_20090203] +synonym: "climbing fibre" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090203 +is_a: GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T11:20:56Z + +[Term] +id: GO:0044302 +name: dentate gyrus mossy fiber +namespace: cellular_component +def: "Distinctive, unmyelinated axons produced by granule cells." [NIF_Subcellular:nlx_subcell_20090601, PMID:17765709] +synonym: "dentate gyrus mossy fibre" EXACT [] +synonym: "granule cell axon" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090601 +is_a: GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T11:23:55Z + +[Term] +id: GO:0044303 +name: axon collateral +namespace: cellular_component +def: "Any of the smaller branches of an axon that emanate from the main axon cylinder." [NIF_Subcellular:sao1470140754] +xref: NIF_Subcellular:sao1470140754 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T11:29:04Z + +[Term] +id: GO:0044304 +name: main axon +namespace: cellular_component +def: "The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites." [NIF_Subcellular:sao1596975044] +synonym: "axon shaft" RELATED [PMID:11264310, PMID:24312009] +synonym: "axon trunk" EXACT [] +synonym: "axonal shaft" RELATED [PMID:11264310, PMID:24312009] +xref: NIF_Subcellular:sao1596975044 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T03:48:17Z + +[Term] +id: GO:0044305 +name: calyx of Held +namespace: cellular_component +def: "The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system." [NIF_Subcellular:sao1684283879, PMID:11823805] +xref: NIF_Subcellular:sao1684283879 +is_a: GO:0043679 ! axon terminus +property_value: RO:0002161 NCBITaxon:8782 +created_by: jl +creation_date: 2010-02-05T02:33:20Z + +[Term] +id: GO:0044306 +name: neuron projection terminus +namespace: cellular_component +def: "The specialized, terminal region of a neuron projection such as an axon or a dendrite." [GOC:jl] +synonym: "nerve terminal" RELATED [PMID:25972809, PMID:9650842] +synonym: "neuron projection terminal" EXACT [] +synonym: "neuron terminal specialization" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043005 ! neuron projection +created_by: jl +creation_date: 2010-02-05T02:44:04Z + +[Term] +id: GO:0044307 +name: dendritic branch +namespace: cellular_component +def: "A dendrite arising from another dendrite." [GOC:aruk, GOC:bc, NIF_Subcellular:sao884265541] +synonym: "dendrite branch" EXACT [] +synonym: "secondary dendrite" NARROW [PMID:25431552] +xref: NIF_Subcellular:sao884265541 +is_a: GO:0030425 ! dendrite +created_by: jl +creation_date: 2010-02-05T04:18:53Z + +[Term] +id: GO:0044308 +name: axonal spine +namespace: cellular_component +def: "A spine that originates from the axon, usually from the initial segment." [NIF_Subcellular:sao18239917] +synonym: "axon spine" EXACT [] +xref: NIF_Subcellular:sao18239917 +is_a: GO:0044309 ! neuron spine +relationship: part_of GO:0030424 ! axon +created_by: jl +creation_date: 2010-02-05T04:22:13Z + +[Term] +id: GO:0044309 +name: neuron spine +namespace: cellular_component +def: "A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck." [ISBN:0198504888, NIF_Subcellular:sao1145756102] +synonym: "spine" BROAD [] +xref: NIF_Subcellular:sao1145756102 +is_a: GO:0043005 ! neuron projection +created_by: jl +creation_date: 2010-02-05T04:25:10Z + +[Term] +id: GO:0044310 +name: osmiophilic body +namespace: cellular_component +def: "A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito." [GOC:jl, PMID:18086189] +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: jl +creation_date: 2010-02-18T03:18:32Z + +[Term] +id: GO:0044311 +name: exoneme +namespace: cellular_component +def: "A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte." [GOC:jl, PMID:18083092, PMID:18083098] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0020007 ! apical complex +created_by: jl +creation_date: 2010-02-18T03:29:56Z + +[Term] +id: GO:0044312 +name: crystalloid +namespace: cellular_component +def: "A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation." [GOC:jl, PMID:19932717] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +created_by: jl +creation_date: 2010-02-18T03:58:55Z + +[Term] +id: GO:0044313 +name: protein K6-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein." [GOC:sp] +is_a: GO:0016579 ! protein deubiquitination +created_by: jl +creation_date: 2010-06-01T03:10:11Z + +[Term] +id: GO:0044314 +name: protein K27-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein." [PMID:19345326] +synonym: "protein K27-linked polyubiquitination" EXACT [GOC:mah] +is_a: GO:0000209 ! protein polyubiquitination +created_by: jl +creation_date: 2010-06-02T11:48:08Z + +[Term] +id: GO:0044315 +name: protein secretion by the type VII secretion system +namespace: biological_process +def: "The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system." [PMID:17922044, PMID:19876390] +is_a: GO:0009306 ! protein secretion +is_a: GO:0071806 ! protein transmembrane transport +created_by: jl +creation_date: 2010-06-02T11:57:05Z + +[Term] +id: GO:0044316 +name: cone cell pedicle +namespace: cellular_component +def: "A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL)." [PMID:10939333] +synonym: "cone pedicle" EXACT [] +is_a: GO:0043679 ! axon terminus +created_by: jl +creation_date: 2010-07-14T01:30:02Z + +[Term] +id: GO:0044317 +name: rod spherule +namespace: cellular_component +def: "A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body." [PMID:26930660] +synonym: "rod cell spherule" EXACT [] +synonym: "rod photoreceptor spherule" EXACT [] +is_a: GO:0043005 ! neuron projection +created_by: jl +creation_date: 2010-07-14T01:38:07Z + +[Term] +id: GO:0044318 +name: L-aspartate:fumarate oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate." [PMID:20149100] +comment: This is based on the finding that L-aspartate oxidase (NadB) of E. coli preferentially uses fumarate as the electron acceptor and does so under anaerobic conditions. The same enzyme uses oxygen as the electron acceptor under aerobic conditions. The EC conflates the two reactions in EC:1.4.3.16 (as they are catalyzed by the same enzyme). +xref: EC:1.4.3.16 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors +created_by: jl +creation_date: 2010-07-14T01:50:01Z + +[Term] +id: GO:0044319 +name: wound healing, spreading of cells +namespace: biological_process +def: "The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface." [GOC:jl] +synonym: "cell migration involved in wound healing epiboly" EXACT [] +is_a: GO:0016477 ! cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0090505 ! epiboly involved in wound healing +relationship: part_of GO:0090505 ! epiboly involved in wound healing +created_by: jl +creation_date: 2010-07-14T02:10:01Z + +[Term] +id: GO:0044320 +name: cellular response to leptin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism." [GOC:yaf] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0044321 ! response to leptin +created_by: jl +creation_date: 2010-07-14T02:21:32Z + +[Term] +id: GO:0044321 +name: response to leptin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]." [GOC:yaf] +synonym: "response to leptin stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +created_by: jl +creation_date: 2010-07-14T02:31:20Z + +[Term] +id: GO:0044322 +name: endoplasmic reticulum quality control compartment +namespace: cellular_component +def: "A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins." [PMID:11408579] +synonym: "ER quality control compartment" EXACT [] +synonym: "ER-derived quality control compartment" RELATED [] +synonym: "ERQC" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005783 ! endoplasmic reticulum +created_by: jl +creation_date: 2010-08-03T01:12:59Z + +[Term] +id: GO:0044323 +name: retinoic acid-responsive element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind." [GOC:jl, GOC:vw, GOC:yaf, PMID:11327309, PMID:19917671] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "RARE binding" EXACT [] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: jl +creation_date: 2010-08-03T03:19:05Z + +[Term] +id: GO:0044324 +name: regulation of transcription involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis." [GOC:jl] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0009948 ! anterior/posterior axis specification +created_by: jl +creation_date: 2010-08-04T12:35:41Z + +[Term] +id: GO:0044325 +name: ion channel binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient." [GOC:BHF, GOC:jl] +subset: goslim_chembl +is_a: GO:0005515 ! protein binding +created_by: jl +creation_date: 2010-08-04T12:52:59Z + +[Term] +id: GO:0044326 +name: dendritic spine neck +namespace: cellular_component +def: "Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine." [GOC:nln] +synonym: "neck" BROAD [NIF_Subcellular:sao1642908940] +synonym: "pedicle" RELATED [NIF_Subcellular:sao1642908940] +synonym: "spine neck" BROAD [NIF_Subcellular:sao1642908940] +xref: NIF_Subcellular:sao1642908940 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043197 ! dendritic spine +created_by: jl +creation_date: 2010-08-18T02:31:15Z + +[Term] +id: GO:0044327 +name: dendritic spine head +namespace: cellular_component +def: "Distal part of the dendritic spine, that carries the post-synaptic density." [GOC:BHF, GOC:nln, GOC:rl] +synonym: "spine head" BROAD [NIF_Subcellular:sao952643730] +xref: NIF_Subcellular:sao952643730 +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0014069 ! postsynaptic density +relationship: part_of GO:0043197 ! dendritic spine +created_by: jl +creation_date: 2010-08-18T02:33:12Z + +[Term] +id: GO:0044328 +name: canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of endothelial cell migration" EXACT [GOC:mah] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0010595 ! positive regulation of endothelial cell migration +relationship: part_of GO:0010595 ! positive regulation of endothelial cell migration +created_by: jl +creation_date: 2010-08-18T04:01:05Z + +[Term] +id: GO:0044329 +name: canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of cell-cell adhesion" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of cell-cell adhesion" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0022409 ! positive regulation of cell-cell adhesion +relationship: part_of GO:0022409 ! positive regulation of cell-cell adhesion +created_by: jl +creation_date: 2010-08-18T04:16:50Z + +[Term] +id: GO:0044330 +name: canonical Wnt signaling pathway involved in positive regulation of wound healing +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of wound healing" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of wound healing" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of wound healing" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0090303 ! positive regulation of wound healing +relationship: part_of GO:0090303 ! positive regulation of wound healing +created_by: jl +creation_date: 2010-08-18T04:21:21Z + +[Term] +id: GO:0044331 +name: cell-cell adhesion mediated by cadherin +namespace: biological_process +def: "The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains." [GOC:ha, GOC:hjd, GOC:jl, PMID:10923970] +is_a: GO:0098609 ! cell-cell adhesion +created_by: jl +creation_date: 2010-08-20T10:24:54Z + +[Term] +id: GO:0044332 +name: Wnt signaling pathway involved in dorsal/ventral axis specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis." [GOC:jl, GOC:yaf] +synonym: "Wnt receptor signaling pathway involved in dorsal/ventral axis specification" EXACT [] +synonym: "Wnt receptor signalling pathway involved in dorsal/ventral axis specification" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in dorsal/ventral axis specification" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0009950 ! dorsal/ventral axis specification +relationship: part_of GO:0009950 ! dorsal/ventral axis specification +created_by: jl +creation_date: 2010-08-20T11:30:30Z + +[Term] +id: GO:0044333 +name: Wnt signaling pathway involved in digestive tract morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract." [GOC:BHF, GOC:jl] +synonym: "Wnt receptor signaling pathway involved in digestive tract morphogenesis" EXACT [] +synonym: "Wnt receptor signalling pathway involved in digestive tract morphogenesis" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in digestive tract morphogenesis" RELATED [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0048546 ! digestive tract morphogenesis +relationship: part_of GO:0048546 ! digestive tract morphogenesis +created_by: jl +creation_date: 2010-08-20T11:36:23Z + +[Term] +id: GO:0044334 +name: canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of epithelial to mesenchymal transition" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of epithelial to mesenchymal transition" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0010718 ! positive regulation of epithelial to mesenchymal transition +relationship: part_of GO:0010718 ! positive regulation of epithelial to mesenchymal transition +created_by: jl +creation_date: 2010-08-20T02:35:17Z + +[Term] +id: GO:0044335 +name: canonical Wnt signaling pathway involved in neural crest cell differentiation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in neural crest cell differentiation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in neural crest cell differentiation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in neural crest cell differentiation" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0014033 ! neural crest cell differentiation +relationship: part_of GO:0014033 ! neural crest cell differentiation +created_by: jl +creation_date: 2010-08-20T03:02:34Z + +[Term] +id: GO:0044336 +name: canonical Wnt signaling pathway involved in negative regulation of apoptotic process +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process." [GOC:BHF, GOC:jl, GOC:mtg_apoptosis] +synonym: "canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis" NARROW [] +synonym: "canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in negative regulation of apoptosis" EXACT [GOC:mah] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0043066 ! negative regulation of apoptotic process +relationship: part_of GO:0043066 ! negative regulation of apoptotic process +created_by: jl +creation_date: 2010-08-20T03:07:53Z + +[Term] +id: GO:0044337 +name: canonical Wnt signaling pathway involved in positive regulation of apoptotic process +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process." [GOC:BHF, GOC:jl, GOC:mtg_apoptosis] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis" NARROW [] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of apoptosis" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of apoptotic process" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0043065 ! positive regulation of apoptotic process +relationship: part_of GO:0043065 ! positive regulation of apoptotic process +created_by: jl +creation_date: 2010-08-20T03:08:24Z + +[Term] +id: GO:0044338 +name: canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0072497 ! mesenchymal stem cell differentiation +relationship: part_of GO:0072497 ! mesenchymal stem cell differentiation +created_by: jl +creation_date: 2010-08-20T03:43:36Z + +[Term] +id: GO:0044339 +name: canonical Wnt signaling pathway involved in osteoblast differentiation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0001649 ! osteoblast differentiation +relationship: part_of GO:0001649 ! osteoblast differentiation +created_by: jl +creation_date: 2010-08-20T03:52:11Z + +[Term] +id: GO:0044340 +name: canonical Wnt signaling pathway involved in regulation of cell proliferation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation." [GOC:BHF, GOC:jl] +synonym: "canonical Wnt receptor signaling pathway involved in regulation of cell proliferation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in regulation of cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in regulation of cell proliferation" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0008283 ! cell population proliferation +relationship: part_of GO:0008283 ! cell population proliferation +relationship: part_of GO:0042127 ! regulation of cell population proliferation +created_by: jl +creation_date: 2010-08-20T03:57:25Z + +[Term] +id: GO:0044341 +name: sodium-dependent phosphate transport +namespace: biological_process +def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions." [GOC:BHF, GOC:jl] +is_a: GO:0006817 ! phosphate ion transport +created_by: jl +creation_date: 2010-08-20T04:16:15Z + +[Term] +id: GO:0044342 +name: type B pancreatic cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] +synonym: "pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "pancreatic beta cell proliferation" EXACT [] +is_a: GO:0050673 ! epithelial cell proliferation +created_by: jl +creation_date: 2010-08-25T01:44:51Z + +[Term] +id: GO:0044343 +name: canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] +synonym: "canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation" RELATED [] +synonym: "canonical Wnt receptor signaling pathway involved in regulation of pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt receptor signaling pathway involved in regulation of type B pancreatic cell proliferation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in regulation of pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt receptor signalling pathway involved in regulation of type B pancreatic cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in regulation of type B pancreatic cell proliferation" EXACT [GOC:signaling] +is_a: GO:0044340 ! canonical Wnt signaling pathway involved in regulation of cell proliferation +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0061469 ! regulation of type B pancreatic cell proliferation +relationship: part_of GO:0061469 ! regulation of type B pancreatic cell proliferation +created_by: jl +creation_date: 2010-08-25T01:53:22Z + +[Term] +id: GO:0044344 +name: cellular response to fibroblast growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus." [GOC:jl, GOC:yaf] +synonym: "cellular response to FGF stimulus" EXACT [] +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:0071774 ! response to fibroblast growth factor +created_by: jl +creation_date: 2010-08-25T02:00:51Z + +[Term] +id: GO:0044345 +name: stromal-epithelial cell signaling involved in prostate gland development +namespace: biological_process +def: "The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development." [GOC:jl, GOC:yaf] +synonym: "stromal-epithelial cell signalling involved in prostate gland development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0030850 ! prostate gland development +created_by: jl +creation_date: 2010-08-25T02:06:34Z + +[Term] +id: GO:0044346 +name: fibroblast apoptotic process +namespace: biological_process +def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf] +synonym: "fibroblast apoptosis" NARROW [] +is_a: GO:0006915 ! apoptotic process +created_by: jl +creation_date: 2010-09-23T11:33:38Z + +[Term] +id: GO:0044347 +name: cell wall polysaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides." [GOC:mengo_curators] +synonym: "cell wall polysaccharide breakdown" EXACT [GOC:mah] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0016998 ! cell wall macromolecule catabolic process +created_by: jl +creation_date: 2011-07-28T01:24:57Z + +[Term] +id: GO:0044348 +name: plant-type cell wall cellulose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall." [GOC:mengo_curators] +synonym: "plant-type cell wall polysaccharide breakdown" EXACT [GOC:mah] +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +is_a: GO:0052541 ! plant-type cell wall cellulose metabolic process +created_by: jl +creation_date: 2011-07-28T01:48:23Z + +[Term] +id: GO:0044349 +name: DNA excision +namespace: biological_process +def: "The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised." [GOC:jl] +is_a: GO:0006259 ! DNA metabolic process +created_by: jl +creation_date: 2011-08-03T10:56:37Z + +[Term] +id: GO:0044350 +name: micropinocytosis +namespace: biological_process +alt_id: GO:1902540 +def: "An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm." [PMID:14731589, PMID:14732047] +synonym: "clathrin-independent pinocytosis" BROAD [] +synonym: "single-organism micropinocytosis" RELATED [] +is_a: GO:0006907 ! pinocytosis +created_by: jl +creation_date: 2013-12-02T14:26:30Z + +[Term] +id: GO:0044351 +name: macropinocytosis +namespace: biological_process +alt_id: GO:1902538 +def: "An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size." [PMID:14732047] +synonym: "clathrin-independent pinocytosis" BROAD [] +synonym: "single-organism macropinocytosis" RELATED [] +is_a: GO:0006907 ! pinocytosis +created_by: jl +creation_date: 2011-08-11T10:26:42Z + +[Term] +id: GO:0044352 +name: pinosome +namespace: cellular_component +def: "A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis." [PMID:14731589, PMID:14732047] +synonym: "pinocytic vesicle" EXACT [NIF_Subcellular:sao1925368674] +xref: NIF_Subcellular:sao1925368674 +is_a: GO:0005768 ! endosome +created_by: jl +creation_date: 2011-08-11T10:51:13Z + +[Term] +id: GO:0044353 +name: micropinosome +namespace: cellular_component +def: "A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis." [PMID:14731589, PMID:14732047] +is_a: GO:0044352 ! pinosome +created_by: jl +creation_date: 2011-08-11T10:51:27Z + +[Term] +id: GO:0044354 +name: macropinosome +namespace: cellular_component +def: "A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis." [PMID:14732047] +is_a: GO:0044352 ! pinosome +created_by: jl +creation_date: 2011-08-11T10:51:42Z + +[Term] +id: GO:0044355 +name: clearance of foreign intracellular DNA +namespace: biological_process +alt_id: GO:0044356 +def: "A defense process that protects an organism from invading foreign DNA." [GO:jl, PMID:20062055] +synonym: "clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine" NARROW [] +is_a: GO:0099046 ! clearance of foreign intracellular nucleic acids +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18727 xsd:anyURI +created_by: jl +creation_date: 2011-08-11T11:25:43Z + +[Term] +id: GO:0044357 +name: regulation of rRNA stability +namespace: biological_process +def: "Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs." [GOC:jl] +synonym: "regulation of ribosomal RNA stability" EXACT [] +is_a: GO:0043487 ! regulation of RNA stability +is_a: GO:1902374 ! regulation of rRNA catabolic process +created_by: jl +creation_date: 2011-08-31T09:57:54Z + +[Term] +id: GO:0044358 +name: envenomation resulting in hemorrhagic damage to other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism." [PMID:10441379, PMID:20614020] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +created_by: jl +creation_date: 2011-10-26T04:24:59Z + +[Term] +id: GO:0044359 +name: modulation of molecular function in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the function of proteins in a second organism." [GOC:jl] +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2011-10-27T01:28:16Z + +[Term] +id: GO:0044360 +name: modulation of voltage-gated potassium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism." [GOC:jl] +is_a: GO:0044363 ! modulation of potassium channel activity in other organism +created_by: jl +creation_date: 2011-10-27T02:09:28Z + +[Term] +id: GO:0044361 +name: negative regulation of voltage-gated potassium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism." [GOC:jl] +is_a: GO:0044360 ! modulation of voltage-gated potassium channel activity in other organism +is_a: GO:0044362 ! negative regulation of molecular function in other organism +created_by: jl +creation_date: 2011-10-27T02:11:52Z + +[Term] +id: GO:0044362 +name: negative regulation of molecular function in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism." [GOC:jl] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0044359 ! modulation of molecular function in other organism +created_by: jl +creation_date: 2011-10-27T02:12:49Z + +[Term] +id: GO:0044363 +name: modulation of potassium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism." [GOC:jl] +is_a: GO:0044561 ! modulation of ion channel activity in other organism +created_by: jl +creation_date: 2011-10-27T02:19:32Z + +[Term] +id: GO:0044364 +name: disruption of cells of other organism +namespace: biological_process +def: "A process in which an organism has a negative effect on the functioning of the second organism's cells." [GOC:jl] +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2011-10-27T02:27:48Z + +[Term] +id: GO:0044365 +name: envenomation resulting in modulation of platelet aggregation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in regulation of platelet aggregation in other organism" EXACT [] +is_a: GO:0044468 ! envenomation resulting in modulation of blood coagulation in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0035892 ! modulation of platelet aggregation in other organism +relationship: has_part GO:0035892 ! modulation of platelet aggregation in other organism +created_by: jl +creation_date: 2011-10-27T02:36:43Z + +[Term] +id: GO:0044373 +name: cytokinin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators." [GOC:jl] +is_a: GO:0042562 ! hormone binding +created_by: jl +creation_date: 2011-12-01T03:42:10Z + +[Term] +id: GO:0044374 +name: sequence-specific DNA binding, bending +namespace: molecular_function +def: "The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:jl, GOC:vw] +synonym: "DNA bending involving sequence-specific DNA binding" EXACT [] +is_a: GO:0008301 ! DNA binding, bending +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding +created_by: jl +creation_date: 2011-12-01T04:05:59Z + +[Term] +id: GO:0044375 +name: regulation of peroxisome size +namespace: biological_process +def: "Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:jl] +is_a: GO:0032535 ! regulation of cellular component size +created_by: jl +creation_date: 2011-12-01T04:37:59Z + +[Term] +id: GO:0044376 +name: obsolete RNA polymerase II complex import to nucleus +namespace: biological_process +alt_id: GO:0098738 +def: "OBSOLETE. The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus." [GOC:dos, GOC:jl] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "DNA-directed RNA polymerase II core complex import into nucleus" EXACT [GO:0098738] +synonym: "DNA-directed RNA polymerase II core complex localization to nucleus" EXACT [] +synonym: "RNA polymerase II complex import into nucleus" EXACT [] +synonym: "RNA polymerase II complex localisation to nucleus" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0006606 +created_by: jl +creation_date: 2011-12-01T04:43:03Z + +[Term] +id: GO:0044377 +name: RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending +namespace: molecular_function +def: "Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:jl, GOC:pg] +synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending" RELATED [] +synonym: "RNA polymerase II promoter proximal region sequence-specific DNA binding, bending" RELATED [] +synonym: "RNA polymerase II proximal promoter region sequence-specific DNA binding, bending" RELATED [] +synonym: "RNA polymerase II proximal promoter sequence-specific DNA binding, bending" RELATED [] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +is_a: GO:0044374 ! sequence-specific DNA binding, bending +created_by: jl +creation_date: 2011-12-08T01:38:21Z + +[Term] +id: GO:0044378 +name: non-sequence-specific DNA binding, bending +namespace: molecular_function +def: "The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:jl, GOC:vw, PMID:20123079] +synonym: "DNA bending involving non-sequence-specific DNA binding" EXACT [] +is_a: GO:0008301 ! DNA binding, bending +created_by: jl +creation_date: 2011-12-08T02:02:13Z + +[Term] +id: GO:0044379 +name: protein localization to actin cortical patch +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, an actin cortical patch." [GOC:mah, PMID:21620704] +synonym: "protein localisation to actin cortical patch" EXACT [GOC:mah] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:1903119 ! protein localization to actin cytoskeleton +created_by: jl +creation_date: 2011-12-08T02:28:42Z + +[Term] +id: GO:0044380 +name: protein localization to cytoskeleton +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl] +synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle +created_by: jl +creation_date: 2011-12-13T11:43:24Z + +[Term] +id: GO:0044381 +name: glucose import in response to insulin stimulus +namespace: biological_process +def: "The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus." [GOC:BHF, PMID:19079291] +synonym: "cellular glucose import in response to insulin stimulus" EXACT [] +is_a: GO:0046323 ! glucose import +relationship: part_of GO:0032869 ! cellular response to insulin stimulus +created_by: jl +creation_date: 2011-12-08T02:44:01Z + +[Term] +id: GO:0044382 +name: CLRC complex localization to heterochromatin +namespace: biological_process +def: "The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation." [GOC:jl] +synonym: "CLRC ubiquitin ligase complex localisation to heterochromatin" EXACT [GOC:mah] +synonym: "CLRC ubiquitin ligase complex localization to heterochromatin" EXACT [] +is_a: GO:0034629 ! cellular protein-containing complex localization +is_a: GO:0097355 ! protein localization to heterochromatin +created_by: jl +creation_date: 2011-12-13T03:37:18Z + +[Term] +id: GO:0044383 +name: host chromosome +namespace: cellular_component +def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell." [GOC:jl] +is_a: GO:0033647 ! host intracellular organelle +created_by: jl +creation_date: 2011-12-13T03:58:38Z + +[Term] +id: GO:0044384 +name: host outer membrane +namespace: cellular_component +def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell." [GOC:jl] +comment: This term covers the outer membrane of the host cell envelope or the outer membrane of a host organelle. For the outer layer of the host cell envelope specifically, see host cell outer membrane ; GO:0039662. +synonym: "host cell outer membrane" RELATED [GOC:bf] +is_a: GO:0033644 ! host cell membrane +created_by: jl +creation_date: 2011-12-13T04:02:07Z + +[Term] +id: GO:0044385 +name: integral to membrane of host cell +namespace: cellular_component +def: "Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell." [GOC:jl] +is_a: GO:0033643 ! host cell part +relationship: part_of GO:0033644 ! host cell membrane +created_by: jl +creation_date: 2011-12-13T04:08:03Z + +[Term] +id: GO:0044386 +name: integral to host endoplasmic reticulum membrane +namespace: cellular_component +def: "Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell." [GOC:jl] +is_a: GO:0044385 ! integral to membrane of host cell +relationship: part_of GO:0044167 ! host cell endoplasmic reticulum membrane +created_by: jl +creation_date: 2011-12-13T04:11:30Z + +[Term] +id: GO:0044387 +name: negative regulation of protein kinase activity by regulation of protein phosphorylation +namespace: biological_process +def: "The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase." [GOC:jl] +is_a: GO:0006469 ! negative regulation of protein kinase activity +created_by: jl +creation_date: 2011-12-13T04:49:36Z + +[Term] +id: GO:0044388 +name: small protein activating enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme." [GOC:jl] +is_a: GO:0019899 ! enzyme binding +created_by: jl +creation_date: 2011-12-15T04:28:17Z + +[Term] +id: GO:0044389 +name: ubiquitin-like protein ligase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-ligase." [GOC:jl] +synonym: "E3 protein ligase binding" EXACT [] +synonym: "small conjugating protein ligase binding" EXACT [GOC:dph] +is_a: GO:0019899 ! enzyme binding +created_by: jl +creation_date: 2011-12-15T04:33:20Z + +[Term] +id: GO:0044390 +name: ubiquitin-like protein conjugating enzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme." [GOC:jl] +synonym: "E2 protein ligase binding" EXACT [] +synonym: "small protein conjugating enzyme binding" EXACT [GOC:dph] +is_a: GO:0019899 ! enzyme binding +created_by: jl +creation_date: 2011-12-15T04:38:44Z + +[Term] +id: GO:0044391 +name: ribosomal subunit +namespace: cellular_component +def: "Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit." [GOC:jl] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005840 ! ribosome +created_by: jl +creation_date: 2011-12-15T04:47:59Z + +[Term] +id: GO:0044392 +name: peptidyl-lysine malonylation +namespace: biological_process +def: "The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine." [GOC:jsg, GOC:sp, PMID:21908771, PMID:22076378, RESID:AA0568] +synonym: "lysine malonylation" EXACT [PMID:21908771] +xref: RESID:AA0568 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0044394 ! protein malonylation +created_by: bf +creation_date: 2011-12-12T09:31:42Z + +[Term] +id: GO:0044393 +name: microspike +namespace: cellular_component +def: "A dynamic, actin-rich projection extending from the surface of a migrating animal cell." [PMID:11429692, PMID:12153987, PMID:19095735] +comment: Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'. +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: bf +creation_date: 2011-12-06T01:31:16Z + +[Term] +id: GO:0044394 +name: protein malonylation +namespace: biological_process +def: "The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group." [GOC:sp] +is_a: GO:0043543 ! protein acylation +created_by: bf +creation_date: 2011-12-12T09:26:37Z + +[Term] +id: GO:0044395 +name: protein targeting to vacuolar membrane +namespace: biological_process +def: "The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein." [GOC:jl] +is_a: GO:0006612 ! protein targeting to membrane +is_a: GO:0006623 ! protein targeting to vacuole +is_a: GO:1903778 ! protein localization to vacuolar membrane +created_by: jl +creation_date: 2011-12-21T02:54:44Z + +[Term] +id: GO:0044396 +name: actin cortical patch organization +namespace: biological_process +def: "A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis." [GOC:jl] +synonym: "actin cortical patch organisation" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization +created_by: jl +creation_date: 2011-12-21T03:33:25Z + +[Term] +id: GO:0044397 +name: actin cortical patch internalization +namespace: biological_process +def: "A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell." [GOC:mah] +is_a: GO:0044396 ! actin cortical patch organization +is_a: GO:0051666 ! actin cortical patch localization +relationship: has_part GO:0030041 ! actin filament polymerization +created_by: jl +creation_date: 2011-12-21T03:37:11Z + +[Term] +id: GO:0044398 +name: envenomation resulting in induction of edema in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation." [GOC:jl, PMID:20562011] +synonym: "envenomation resulting in induction of oedema in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +created_by: jl +creation_date: 2011-12-21T03:57:27Z + +[Term] +id: GO:0044399 +name: multi-species biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:cc, GOC:di, GOC:tb] +is_a: GO:0042710 ! biofilm formation +is_a: GO:0044403 ! symbiotic process + +[Term] +id: GO:0044400 +name: multi-species biofilm formation on inanimate substrate +namespace: biological_process +def: "A process in which microorganisms of different species attach to and grow on an inanimate surface such as a rock or pipe and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:cc] +is_a: GO:0090608 ! multi-species submerged biofilm formation + +[Term] +id: GO:0044401 +name: multi-species biofilm formation in or on host organism +namespace: biological_process +def: "A process in which microorganisms of different species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +is_a: GO:0044406 ! adhesion of symbiont to host +is_a: GO:0090608 ! multi-species submerged biofilm formation + +[Term] +id: GO:0044402 +name: obsolete competition with other organism +namespace: biological_process +def: "OBSOLETE. Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community." [GOC:cc] +comment: This term was obsoleted because it is outside the scope of GO. +synonym: "competition with another organism" EXACT [GOC:bf] +synonym: "interspecies competition" BROAD [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18568 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0044403 +name: symbiotic process +namespace: biological_process +alt_id: GO:0043298 +alt_id: GO:0044404 +alt_id: GO:0072519 +alt_id: GO:0085031 +def: "A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts." [GOC:cc, https://study.com/academy/lesson/symbiont-definition-lesson-quiz.html] +subset: goslim_chembl +subset: goslim_generic +synonym: "commensalism" NARROW [] +synonym: "host-pathogen interaction" NARROW [] +synonym: "parasitism" NARROW [] +synonym: "symbiosis" RELATED [] +synonym: "symbiosis, encompassing mutualism through parasitism" RELATED [] +synonym: "symbiotic interaction" RELATED [] +synonym: "symbiotic interaction between host and organism" RELATED [] +synonym: "symbiotic interaction between organisms" RELATED [] +synonym: "symbiotic interaction between species" RELATED [] +is_a: GO:0044419 ! interspecies interaction between organisms +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14807 xsd:anyURI + +[Term] +id: GO:0044405 +name: detection of host +namespace: biological_process +def: "The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "recognition of host" EXACT [] +is_a: GO:0075136 ! response to host +is_a: GO:0098543 ! detection of other organism + +[Term] +id: GO:0044406 +name: adhesion of symbiont to host +namespace: biological_process +alt_id: GO:0051825 +alt_id: GO:0051856 +def: "The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:cc, GOC:dos, GOC:jl] +comment: This term can be used to annotate both symbiont and host organisms. Consider also annotating to interaction with host ; GO:0051702, or interaction with symbiont ; GO:0051702. +synonym: "adhesion to host" NARROW [] +synonym: "adhesion to other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "adhesion to other organism involved in symbiotic interaction" EXACT [] +synonym: "adhesion to symbiont" NARROW [] +synonym: "host adhesion" NARROW [] +is_a: GO:0022610 ! biological adhesion +is_a: GO:0044403 ! symbiotic process + +[Term] +id: GO:0044407 +name: single-species biofilm formation in or on host organism +namespace: biological_process +def: "A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +is_a: GO:0044010 ! single-species biofilm formation +is_a: GO:0044406 ! adhesion of symbiont to host + +[Term] +id: GO:0044408 +name: obsolete growth or development of symbiont on or near host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism." [GOC:cc] +synonym: "growth or development of organism on or near host surface" EXACT [] +synonym: "growth or development of symbiont on or near host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044409 +name: entry into host +namespace: biological_process +alt_id: GO:0030260 +alt_id: GO:0044411 +alt_id: GO:0051806 +alt_id: GO:0051828 +alt_id: GO:0051830 +alt_id: GO:0075052 +alt_id: GO:0085027 +alt_id: GO:0085028 +def: "Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:vw] +synonym: "entry into cell of other organism during symbiotic interaction" NARROW [GOC:tb] +synonym: "entry into cell of other organism involved in symbiotic interaction" RELATED [] +synonym: "entry into host cell" NARROW [] +synonym: "entry into host cell via penetration peg" NARROW [] +synonym: "entry into host through host barriers" RELATED [] +synonym: "entry into host via a specialized structure during symbiotic interaction" NARROW [] +synonym: "entry into host via enzymatic degradation of host anatomical structure" NARROW [] +synonym: "entry into host via enzymatic degradation of host cuticle" NARROW [] +synonym: "entry into other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "entry into other organism involved in symbiotic interaction" RELATED [] +synonym: "host cell invasion" NARROW [] +synonym: "host invasion" EXACT [] +synonym: "host penetration" EXACT [GOC:vw] +synonym: "invasion into host" EXACT [] +synonym: "invasion into other organism" RELATED [] +synonym: "invasion of host" EXACT [] +synonym: "invasion of other organism" RELATED [] +synonym: "invasive growth" RELATED [] +synonym: "other organism cell invasion" NARROW [] +synonym: "other organism invasion" RELATED [] +synonym: "penetration into host" EXACT [GOC:vw] +synonym: "penetration into host via a specialized structure" NARROW [GOC:vw] +synonym: "penetration into host via a specialized structure during symbiotic interaction" NARROW [GOC:vw] +is_a: GO:0052126 ! movement in host environment +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18563 xsd:anyURI + +[Term] +id: GO:0044410 +name: entry into host through natural portals +namespace: biological_process +alt_id: GO:0051829 +def: "Penetration by a symbiont into a host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "entry into other organism through natural portals during symbiotic interaction" RELATED [GOC:tb] +synonym: "entry into other organism through natural portals involved in symbiotic interaction" RELATED [] +is_a: GO:0044409 ! entry into host + +[Term] +id: GO:0044412 +name: obsolete growth or development of symbiont in host +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host ; GO:0044114' and 'growth of symbiont in host ; GO:0044117'. +synonym: "growth or development of organism within host" EXACT [] +synonym: "growth or development of symbiont in host" EXACT [] +synonym: "growth or development of symbiont within host" EXACT [] +synonym: "invasive growth" BROAD [] +is_obsolete: true +consider: GO:0044114 +consider: GO:0044117 + +[Term] +id: GO:0044414 +name: suppression of host defenses by symbiont +namespace: biological_process +alt_id: GO:0051833 +alt_id: GO:0052037 +alt_id: GO:0052261 +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "down regulation by organism of defense response of other organism during symbiotic interaction" RELATED [] +synonym: "down regulation by symbiont of host defense response" EXACT [] +synonym: "down-regulation by organism of defense response of other organism during symbiotic interaction" RELATED [] +synonym: "down-regulation by symbiont of host defense response" EXACT [] +synonym: "downregulation by organism of defense response of other organism during symbiotic interaction" RELATED [] +synonym: "downregulation by symbiont of host defense response" EXACT [] +synonym: "inhibition by organism of defense response of other organism during symbiotic interaction" NARROW [] +synonym: "inhibition by symbiont of host defense response" NARROW [] +synonym: "negative regulation by organism of defense response of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "negative regulation by organism of defense response of other organism involved in symbiotic interaction" EXACT [] +synonym: "negative regulation by symbiont of host defense response" EXACT [] +synonym: "negative regulation of host defenses" EXACT [] +synonym: "suppression of defense response of other organism" EXACT [] +synonym: "suppression of defense response of other organism involved in symbiotic interaction" RELATED [] +synonym: "suppression of defenses of other organism involved in symbiotic interaction" BROAD [] +synonym: "suppression of host defense response" EXACT [] +is_a: GO:0030682 ! mitigation of host defenses by symbiont +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0044416 +name: induction by symbiont of host defense response +namespace: biological_process +alt_id: GO:0052251 +alt_id: GO:0052509 +alt_id: GO:0052510 +def: "The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "activation by symbiont of host defense response" EXACT [] +synonym: "activation of host defense response" EXACT [] +synonym: "induction by organism of defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of host defense response" RELATED [] +synonym: "stimulation by symbiont of host defense response" RELATED [] +synonym: "up regulation by symbiont of host defense response" RELATED [] +synonym: "up-regulation by symbiont of host defense response" RELATED [] +synonym: "upregulation by symbiont of host defense response" RELATED [] +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0044417 +name: translocation of molecules into host +namespace: biological_process +alt_id: GO:0051836 +def: "The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "translocation of molecules into other organism during symbiotic interaction" BROAD [GOC:dph] +synonym: "translocation of molecules into other organism involved in symbiotic interaction" BROAD [] +synonym: "transport of molecules into host" EXACT [] +synonym: "transport of molecules into other organism during symbiotic interaction" BROAD [] +is_a: GO:0051701 ! interaction with host + +[Term] +id: GO:0044418 +name: translocation of DNA into host +namespace: biological_process +alt_id: GO:0051837 +def: "The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "translocation of DNA into other organism during symbiotic interaction" BROAD [GOC:tb] +synonym: "translocation of DNA into other organism involved in symbiotic interaction" BROAD [] +synonym: "transport of DNA into host" EXACT [] +synonym: "transport of DNA into other organism during symbiotic interaction" BROAD [] +is_a: GO:0044417 ! translocation of molecules into host + +[Term] +id: GO:0044419 +name: interspecies interaction between organisms +namespace: biological_process +def: "Any process in which an organism has an effect on an organism of a different species." [GOC:cc] +subset: goslim_candida +subset: goslim_pir +synonym: "interaction with another species" EXACT [] +synonym: "interspecies interaction" EXACT [] +synonym: "interspecies interaction with other organisms" EXACT [] +is_a: GO:0008150 ! biological_process +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0044420 +name: obsolete extracellular matrix component +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants)." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "extracellular matrix part" EXACT [] +is_obsolete: true +consider: GO:0031012 + +[Term] +id: GO:0044421 +name: obsolete extracellular region part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "extracellular structure" RELATED [NIF_Subcellular:sao9117790637] +xref: NIF_Subcellular:sao9117790637 +is_obsolete: true +consider: GO:0005576 + +[Term] +id: GO:0044422 +name: obsolete organelle part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0043226 + +[Term] +id: GO:0044423 +name: virion part +namespace: cellular_component +def: "Any constituent part of a virion, a complete fully infectious extracellular virus particle." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_a: GO:0005575 ! cellular_component +intersection_of: GO:0005575 ! cellular_component +intersection_of: part_of GO:0019012 ! virion +relationship: part_of GO:0019012 ! virion +property_value: RO:0002161 NCBITaxon:131567 + +[Term] +id: GO:0044424 +name: obsolete intracellular part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0005622 + +[Term] +id: GO:0044425 +name: obsolete membrane part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0016020 + +[Term] +id: GO:0044426 +name: obsolete cell wall part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0005618 + +[Term] +id: GO:0044427 +name: obsolete chromosomal part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "chromosomal component" EXACT [] +synonym: "chromosome component" EXACT [] +synonym: "chromosome part" EXACT [] +is_obsolete: true +consider: GO:0005694 + +[Term] +id: GO:0044428 +name: obsolete nuclear part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "nuclear subcomponent" EXACT [NIF_Subcellular:sao1499850686] +synonym: "nucleus component" EXACT [] +xref: NIF_Subcellular:sao1499850686 +is_obsolete: true +consider: GO:0005634 + +[Term] +id: GO:0044429 +name: obsolete mitochondrial part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "mitochondrial subcomponent" EXACT [NIF_Subcellular:sao666410040] +synonym: "mitochondrion component" EXACT [] +xref: NIF_Subcellular:sao666410040 +is_obsolete: true +consider: GO:0005739 + +[Term] +id: GO:0044430 +name: obsolete cytoskeletal part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "cytoskeletal element" EXACT [NIF_Subcellular:sao1635329413] +synonym: "cytoskeleton component" EXACT [] +xref: NIF_Subcellular:sao1635329413 +is_obsolete: true +consider: GO:0005856 + +[Term] +id: GO:0044431 +name: obsolete Golgi apparatus part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "Golgi component" EXACT [] +synonym: "Golgi subcomponent" EXACT [NIF_Subcellular:sao624292949] +xref: NIF_Subcellular:sao624292949 +is_obsolete: true +consider: GO:0005794 + +[Term] +id: GO:0044432 +name: obsolete endoplasmic reticulum part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "ER component" EXACT [] +is_obsolete: true +consider: GO:0005783 + +[Term] +id: GO:0044433 +name: obsolete cytoplasmic vesicle part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0031410 + +[Term] +id: GO:0044434 +name: obsolete chloroplast part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0009507 + +[Term] +id: GO:0044435 +name: obsolete plastid part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0009536 + +[Term] +id: GO:0044436 +name: obsolete thylakoid part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0009579 + +[Term] +id: GO:0044437 +name: obsolete vacuolar part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "vacuole component" EXACT [] +is_obsolete: true +consider: GO:0005773 + +[Term] +id: GO:0044438 +name: obsolete microbody part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0042579 + +[Term] +id: GO:0044439 +name: obsolete peroxisomal part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2)." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "peroxisome component" EXACT [] +is_obsolete: true +consider: GO:0005777 + +[Term] +id: GO:0044440 +name: obsolete endosomal part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered." [GOC:mah, PMID:19696797] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "endosomal subcomponent" EXACT [NIF_Subcellular:sao1683772610] +synonym: "endosome component" EXACT [] +xref: NIF_Subcellular:sao1683772610 +is_obsolete: true +consider: GO:0005768 + +[Term] +id: GO:0044441 +name: obsolete ciliary part +namespace: cellular_component +alt_id: GO:0044442 +def: "OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent. +subset: gocheck_do_not_annotate +synonym: "cilial part" EXACT [] +synonym: "cilium part" EXACT [] +synonym: "flagellar part" NARROW [] +synonym: "flagellum component" NARROW [] +synonym: "flagellum part" NARROW [] +synonym: "microtubule-based flagellum part" EXACT [] +is_obsolete: true +consider: GO:0005929 + +[Term] +id: GO:0044443 +name: obsolete pilus part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter." [GOC:pamgo_curators] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "fimbrial part" EXACT [] +synonym: "fimbrium component" EXACT [] +synonym: "pilus component" EXACT [] +is_obsolete: true +consider: GO:0009289 + +[Term] +id: GO:0044444 +name: obsolete cytoplasmic part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "cytoplasm component" EXACT [] +is_obsolete: true +consider: GO:0005737 + +[Term] +id: GO:0044445 +name: obsolete cytosolic part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "cytosol component" EXACT [] +is_obsolete: true +consider: GO:0005829 + +[Term] +id: GO:0044446 +name: obsolete intracellular organelle part +namespace: cellular_component +def: "OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0043229 + +[Term] +id: GO:0044447 +name: obsolete axoneme part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:cilia, GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent. +subset: gocheck_do_not_annotate +synonym: "axonemal part" EXACT [] +is_obsolete: true +consider: GO:0005930 + +[Term] +id: GO:0044448 +name: obsolete cell cortex part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0005938 + +[Term] +id: GO:0044449 +name: obsolete contractile fiber part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "contractile fibre component" EXACT [] +synonym: "muscle fiber component" BROAD [] +synonym: "muscle fibre component" BROAD [] +is_obsolete: true +consider: GO:0043292 + +[Term] +id: GO:0044450 +name: obsolete microtubule organizing center part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "microtubule organizing centre component" EXACT [] +synonym: "MTOC component" EXACT [] +is_obsolete: true +consider: GO:0005815 + +[Term] +id: GO:0044451 +name: obsolete nucleoplasm part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0005654 + +[Term] +id: GO:0044452 +name: obsolete nucleolar part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "nucleolus component" EXACT [] +is_obsolete: true +consider: GO:0005730 + +[Term] +id: GO:0044453 +name: obsolete nuclear membrane part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0031965 + +[Term] +id: GO:0044454 +name: obsolete nuclear chromosome part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0000228 + +[Term] +id: GO:0044455 +name: obsolete mitochondrial membrane part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0031966 + +[Term] +id: GO:0044456 +name: obsolete synapse part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "synaptic component" RELATED [NIF_Subcellular:sao1784069613] +xref: NIF_Subcellular:sao1784069613 +is_obsolete: true +consider: GO:0045202 + +[Term] +id: GO:0044457 +name: obsolete cell septum part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0030428 + +[Term] +id: GO:0044458 +name: motile cilium assembly +namespace: biological_process +alt_id: GO:1903887 +def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf] +synonym: "motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "motile primary cilium assembly" RELATED [] +synonym: "motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "nodal cilium formation" RELATED [GOC:TermGenie] +is_a: GO:0060271 ! cilium assembly +created_by: krc +creation_date: 2015-02-06T17:23:23Z + +[Term] +id: GO:0044459 +name: obsolete plasma membrane part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0005886 + +[Term] +id: GO:0044460 +name: obsolete flagellum part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium." [GOC:jl] +comment: This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum part ; GO:0044461'. +synonym: "flagellum component" EXACT [] +synonym: "flagellum part" EXACT [] +is_obsolete: true + +[Term] +id: GO:0044461 +name: obsolete bacterial-type flagellum part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential." [DOI:10.1002/9780470015902.a0000744.pub4, GOC:cilia, GOC:jl, GOC:mtg_sensu, PMID:10572114, PMID:12624192, PMID:25251856] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "flagellin-based flagellum part" EXACT [] +is_obsolete: true +consider: GO:0009288 + +[Term] +id: GO:0044462 +name: obsolete external encapsulating structure part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria)." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0030312 + +[Term] +id: GO:0044463 +name: obsolete cell projection part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0042995 + +[Term] +id: GO:0044464 +name: obsolete cell part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +subset: goslim_pir +synonym: "cellular subcomponent" EXACT [NIF_Subcellular:sao628508602] +synonym: "protoplast" RELATED [GOC:mah] +xref: NIF_Subcellular:sao628508602 +is_obsolete: true +consider: CL:0000000 + +[Term] +id: GO:0044465 +name: modulation of sensory perception of pain in other organism +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism." [GOC:ed, PMID:18579526] +synonym: "regulation of sensory perception of pain in another organism" EXACT [] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:0051930 ! regulation of sensory perception of pain +created_by: jl +creation_date: 2012-01-12T03:14:19Z + +[Term] +id: GO:0044466 +name: glutaryl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate." [GOC:pm, PMID:16141203, RHEA:13389] +synonym: "glutaryl-CoA thioesterase activity" EXACT [] +xref: EC:1.3.8.6 +xref: RHEA:13389 +is_a: GO:0047617 ! acyl-CoA hydrolase activity +created_by: jl +creation_date: 2012-01-17T04:16:43Z + +[Term] +id: GO:0044467 +name: glial cell-derived neurotrophic factor secretion +namespace: biological_process +def: "The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons." [GOC:yaf, PMID:17505307] +synonym: "GDNF secretion" EXACT [] +synonym: "glial cell line-derived neurotrophic factor secretion" RELATED [] +is_a: GO:0050663 ! cytokine secretion +created_by: jl +creation_date: 2012-01-17T04:26:05Z + +[Term] +id: GO:0044468 +name: envenomation resulting in modulation of blood coagulation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism." [GOC:jl] +synonym: "envenomation resulting in regulation of blood coagulation in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0035806 ! modulation of blood coagulation in other organism +relationship: has_part GO:0035806 ! modulation of blood coagulation in other organism +created_by: jl +creation_date: 2012-01-19T01:24:10Z + +[Term] +id: GO:0044469 +name: envenomation resulting in positive regulation of blood coagulation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism." [GOC:jl] +is_a: GO:0044468 ! envenomation resulting in modulation of blood coagulation in other organism +is_a: GO:0044483 ! envenomation resulting in impairment of hemostasis in other organism +relationship: has_part GO:0035807 ! positive regulation of blood coagulation in other organism +created_by: jl +creation_date: 2012-01-19T01:29:09Z + +[Term] +id: GO:0044470 +name: envenomation resulting in negative regulation of blood coagulation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism." [GOC:jl] +is_a: GO:0044468 ! envenomation resulting in modulation of blood coagulation in other organism +is_a: GO:0044483 ! envenomation resulting in impairment of hemostasis in other organism +relationship: has_part GO:0035899 ! negative regulation of blood coagulation in other organism +created_by: jl +creation_date: 2012-01-19T01:32:48Z + +[Term] +id: GO:0044471 +name: envenomation resulting in pore formation in membrane of other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism." [GOC:fj, GOC:jl, PMID:21549739] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0035915 ! pore formation in membrane of other organism +created_by: jl +creation_date: 2012-01-19T01:39:47Z + +[Term] +id: GO:0044472 +name: envenomation resulting in modulation of calcium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:20920515] +is_a: GO:0044560 ! envenomation resulting in modulation of ion channel activity in other organism +relationship: has_part GO:0035916 ! modulation of calcium channel activity in other organism +created_by: jl +creation_date: 2012-01-19T02:17:25Z + +[Term] +id: GO:0044473 +name: envenomation resulting in negative regulation of calcium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:20920515] +is_a: GO:0044472 ! envenomation resulting in modulation of calcium channel activity in other organism +relationship: has_part GO:0035917 ! negative regulation of calcium channel activity in other organism +created_by: jl +creation_date: 2012-01-19T02:19:46Z + +[Term] +id: GO:0044474 +name: envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:20920515] +is_a: GO:0044473 ! envenomation resulting in negative regulation of calcium channel activity in other organism +relationship: has_part GO:0035918 ! negative regulation of voltage-gated calcium channel activity in other organism +created_by: jl +creation_date: 2012-01-19T02:25:04Z + +[Term] +id: GO:0044475 +name: envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:20920515] +is_a: GO:0044474 ! envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism +relationship: has_part GO:0035920 ! negative regulation of high voltage-gated calcium channel activity in other organism +created_by: jl +creation_date: 2012-01-19T02:28:11Z + +[Term] +id: GO:0044476 +name: envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:20920515] +is_a: GO:0044474 ! envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism +relationship: has_part GO:0035919 ! negative regulation of low voltage-gated calcium channel activity in other organism +created_by: jl +creation_date: 2012-01-19T02:28:42Z + +[Term] +id: GO:0044477 +name: envenomation resulting in negative regulation of platelet aggregation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism." [GOC:fj, GOC:jl] +is_a: GO:0044365 ! envenomation resulting in modulation of platelet aggregation in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0035893 ! negative regulation of platelet aggregation in other organism +relationship: has_part GO:0035893 ! negative regulation of platelet aggregation in other organism +created_by: jl +creation_date: 2012-01-19T02:36:44Z + +[Term] +id: GO:0044478 +name: envenomation resulting in positive regulation of platelet aggregation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism." [GOC:fj, GOC:jl] +is_a: GO:0044365 ! envenomation resulting in modulation of platelet aggregation in other organism +is_a: GO:0044469 ! envenomation resulting in positive regulation of blood coagulation in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0035894 ! positive regulation of platelet aggregation in other organism +relationship: has_part GO:0035894 ! positive regulation of platelet aggregation in other organism +created_by: jl +creation_date: 2012-01-19T02:39:45Z + +[Term] +id: GO:0044479 +name: envenomation resulting in modulation of mast cell degranulation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism." [GOC:fj, GOC:jl, PMID:21549739] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0035895 ! modulation of mast cell degranulation in other organism +created_by: jl +creation_date: 2012-01-19T02:51:51Z + +[Term] +id: GO:0044480 +name: envenomation resulting in positive regulation of mast cell degranulation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism." [GOC:fj, GOC:jl, PMID:21549739] +is_a: GO:0044479 ! envenomation resulting in modulation of mast cell degranulation in other organism +relationship: has_part GO:0035896 ! positive regulation of mast cell degranulation in other organism +created_by: jl +creation_date: 2012-01-19T02:54:37Z + +[Term] +id: GO:0044481 +name: envenomation resulting in proteolysis in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism." [GOC:fj, GOC:jl, PMID:15922779] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0035897 ! proteolysis in other organism +created_by: jl +creation_date: 2012-01-19T03:01:16Z + +[Term] +id: GO:0044482 +name: envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism." [GOC:fj, GOC:jl, PMID:10441379, PMID:19485419] +synonym: "envenomation resulting in blood vessel ECM, causing hemorrhagic damage in other organism" EXACT [] +is_a: GO:0044358 ! envenomation resulting in hemorrhagic damage to other organism +created_by: jl +creation_date: 2012-01-19T03:12:04Z + +[Term] +id: GO:0044483 +name: envenomation resulting in impairment of hemostasis in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in negative regulation of hemostasis in other organism" EXACT [] +synonym: "envenomation, impairing hemostasis in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +created_by: jl +creation_date: 2012-01-19T03:15:56Z + +[Term] +id: GO:0044484 +name: envenomation resulting in fibrinolysis in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:17433397, PMID:17544404] +is_a: GO:0044483 ! envenomation resulting in impairment of hemostasis in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0042730 ! fibrinolysis +relationship: has_part GO:0042730 ! fibrinolysis +created_by: jl +creation_date: 2012-01-26T03:26:33Z + +[Term] +id: GO:0044485 +name: envenomation resulting in fibrinogenolysis in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:17433397, PMID:17544404] +is_a: GO:0044536 ! envenomation resulting in depletion of circulating fibrinogen in other organism +created_by: jl +creation_date: 2012-01-26T03:41:01Z + +[Term] +id: GO:0044486 +name: modulation of transmission of nerve impulse in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the transmission of a nerve impulse in another organism." [GOC:jl] +synonym: "modulation of conduction of nerve impulse in other organism" EXACT [GOC:dph] +synonym: "regulation of transmission of nerve impulse in other organism" EXACT [] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:0051969 ! regulation of transmission of nerve impulse +created_by: jl +creation_date: 2012-01-26T04:03:31Z + +[Term] +id: GO:0044487 +name: envenomation resulting in modulation of transmission of nerve impulse in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in modulation of conduction of nerve impulse in other organism" EXACT [GOC:dph] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044486 ! modulation of transmission of nerve impulse in other organism +created_by: jl +creation_date: 2012-01-26T05:01:54Z + +[Term] +id: GO:0044488 +name: modulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044561 ! modulation of ion channel activity in other organism +created_by: jl +creation_date: 2012-02-01T11:48:25Z + +[Term] +id: GO:0044489 +name: negative regulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044362 ! negative regulation of molecular function in other organism +is_a: GO:0044488 ! modulation of voltage-gated sodium channel activity in other organism +created_by: jl +creation_date: 2012-02-01T12:21:02Z + +[Term] +id: GO:0044490 +name: positive regulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044488 ! modulation of voltage-gated sodium channel activity in other organism +is_a: GO:0044491 ! positive regulation of molecular function in other organism +created_by: jl +creation_date: 2012-02-01T12:21:26Z + +[Term] +id: GO:0044491 +name: positive regulation of molecular function in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism." [GOC:jl] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0044359 ! modulation of molecular function in other organism +created_by: jl +creation_date: 2012-02-01T12:21:51Z + +[Term] +id: GO:0044492 +name: envenomation resulting in modulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044560 ! envenomation resulting in modulation of ion channel activity in other organism +relationship: has_part GO:0044488 ! modulation of voltage-gated sodium channel activity in other organism +created_by: jl +creation_date: 2012-02-01T01:23:04Z + +[Term] +id: GO:0044493 +name: envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044492 ! envenomation resulting in modulation of voltage-gated sodium channel activity in other organism +relationship: has_part GO:0044489 ! negative regulation of voltage-gated sodium channel activity in other organism +created_by: jl +creation_date: 2012-02-01T01:26:59Z + +[Term] +id: GO:0044494 +name: envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism." [GOC:fj, GOC:jl, PMID:21781281] +is_a: GO:0044492 ! envenomation resulting in modulation of voltage-gated sodium channel activity in other organism +relationship: has_part GO:0044490 ! positive regulation of voltage-gated sodium channel activity in other organism +created_by: jl +creation_date: 2012-02-01T01:29:25Z + +[Term] +id: GO:0044495 +name: modulation of blood pressure in other organism +namespace: biological_process +def: "A process by which one organism modulates the force with which blood travels through the circulatory system of another organism." [GOC:fj, GOC:jl, PMID:19837656] +synonym: "regulation of blood pressure in other organism" EXACT [] +is_a: GO:0008217 ! regulation of blood pressure +created_by: jl +creation_date: 2012-02-01T02:10:15Z + +[Term] +id: GO:0044496 +name: negative regulation of blood pressure in other organism +namespace: biological_process +def: "A process by which one organism decreases the force with which blood travels through the circulatory system of another organism." [GOC:fj, GOC:jl, PMID:19837656] +is_a: GO:0044495 ! modulation of blood pressure in other organism +is_a: GO:0045776 ! negative regulation of blood pressure +created_by: jl +creation_date: 2012-02-01T02:15:28Z + +[Term] +id: GO:0044497 +name: positive regulation of blood pressure in other organism +namespace: biological_process +def: "A process by which one organism increases the force with which blood travels through the circulatory system of another organism." [GOC:fj, GOC:jl, PMID:19837656] +is_a: GO:0044495 ! modulation of blood pressure in other organism +is_a: GO:0045777 ! positive regulation of blood pressure +created_by: jl +creation_date: 2012-02-01T02:17:21Z + +[Term] +id: GO:0044498 +name: envenomation resulting in modulation of blood pressure in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:19837656] +synonym: "envenomation resulting in regulation of blood pressure in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0044495 ! modulation of blood pressure in other organism +relationship: has_part GO:0044495 ! modulation of blood pressure in other organism +created_by: jl +creation_date: 2012-02-01T02:21:27Z + +[Term] +id: GO:0044499 +name: envenomation resulting in positive regulation of blood pressure in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:19837656] +is_a: GO:0044498 ! envenomation resulting in modulation of blood pressure in other organism +relationship: has_part GO:0044497 ! positive regulation of blood pressure in other organism +created_by: jl +creation_date: 2012-02-01T02:39:06Z + +[Term] +id: GO:0044500 +name: envenomation resulting in negative regulation of blood pressure in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:19837656] +synonym: "hypotensive activity in other organism" EXACT [] +is_a: GO:0044498 ! envenomation resulting in modulation of blood pressure in other organism +relationship: has_part GO:0044496 ! negative regulation of blood pressure in other organism +created_by: jl +creation_date: 2012-02-01T02:40:50Z + +[Term] +id: GO:0044501 +name: modulation of signal transduction in other organism +namespace: biological_process +def: "The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism." [GOC:fj, GOC:jl] +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2012-02-23T03:48:19Z + +[Term] +id: GO:0044503 +name: modulation of G protein-coupled receptor activity in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +synonym: "modulation of G-protein coupled receptor activity in other organism" EXACT [] +is_a: GO:0044504 ! modulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-23T04:20:07Z + +[Term] +id: GO:0044504 +name: modulation of receptor activity in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the activity of a receptor in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044359 ! modulation of molecular function in other organism +created_by: jl +creation_date: 2012-02-23T04:21:41Z + +[Term] +id: GO:0044505 +name: positive regulation of G protein-coupled receptor activity in other organism +namespace: biological_process +def: "A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +synonym: "positive regulation of G-protein coupled receptor activity in other organism" EXACT [] +synonym: "regulation of G-protein coupled receptor activity in other organism" EXACT [] +is_a: GO:0044503 ! modulation of G protein-coupled receptor activity in other organism +is_a: GO:0044507 ! positive regulation of receptor activity in other organism +is_a: GO:2000273 ! positive regulation of signaling receptor activity +created_by: jl +creation_date: 2012-02-23T04:24:17Z + +[Term] +id: GO:0044506 +name: modulation of glucagon-like peptide receptor 1 activity in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +synonym: "regulation of glucagon-like peptide receptor activity in other organism" EXACT [] +is_a: GO:0044504 ! modulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-23T04:29:14Z + +[Term] +id: GO:0044507 +name: positive regulation of receptor activity in other organism +namespace: biological_process +def: "A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044491 ! positive regulation of molecular function in other organism +is_a: GO:0044504 ! modulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-23T04:31:52Z + +[Term] +id: GO:0044508 +name: glucagon-like peptide 1 receptor activity +namespace: molecular_function +def: "Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein." [GOC:jl, PMID:12529935] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +created_by: jl +creation_date: 2012-02-23T04:50:25Z + +[Term] +id: GO:0044509 +name: envenomation resulting in modulation of signal transduction in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044501 ! modulation of signal transduction in other organism +created_by: jl +creation_date: 2012-02-23T04:58:10Z + +[Term] +id: GO:0044510 +name: envenomation resulting in positive regulation of signal transduction in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044509 ! envenomation resulting in modulation of signal transduction in other organism +relationship: has_part GO:0052028 ! induction by symbiont of host signal transduction pathway +created_by: jl +creation_date: 2012-02-23T05:03:22Z + +[Term] +id: GO:0044511 +name: envenomation resulting in modulation of receptor activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044504 ! modulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T10:12:24Z + +[Term] +id: GO:0044512 +name: envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044511 ! envenomation resulting in modulation of receptor activity in other organism +relationship: has_part GO:0044506 ! modulation of glucagon-like peptide receptor 1 activity in other organism +created_by: jl +creation_date: 2012-02-26T10:20:19Z + +[Term] +id: GO:0044513 +name: envenomation resulting in modulation of G protein-coupled receptor activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +synonym: "envenomation resulting in modulation of G-protein coupled receptor activity in other organism" EXACT [] +is_a: GO:0044511 ! envenomation resulting in modulation of receptor activity in other organism +relationship: has_part GO:0044503 ! modulation of G protein-coupled receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:02:17Z + +[Term] +id: GO:0044514 +name: envenomation resulting in positive regulation of G protein-coupled receptor activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +synonym: "envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism" EXACT [] +is_a: GO:0044513 ! envenomation resulting in modulation of G protein-coupled receptor activity in other organism +relationship: has_part GO:0044505 ! positive regulation of G protein-coupled receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:06:15Z + +[Term] +id: GO:0044515 +name: envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044512 ! envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism +relationship: has_part GO:0044516 ! positive regulation of glucagon-like peptide receptor 1 activity in other organism +created_by: jl +creation_date: 2012-02-26T11:08:08Z + +[Term] +id: GO:0044516 +name: positive regulation of glucagon-like peptide receptor 1 activity in other organism +namespace: biological_process +def: "A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism." [GOC:fj, GOC:jl, PMID:8405712] +is_a: GO:0044506 ! modulation of glucagon-like peptide receptor 1 activity in other organism +is_a: GO:0044507 ! positive regulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:09:44Z + +[Term] +id: GO:0044517 +name: modulation of vasoactive intestinal polypeptide receptor activity in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism." [GOC:fj, GOC:jl] +synonym: "modulation of VIP receptor activity in other organism" EXACT [] +synonym: "regulation of vasoactive intestinal polypeptide receptor activity in other organism" EXACT [] +is_a: GO:0044504 ! modulation of receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:48:32Z + +[Term] +id: GO:0044518 +name: positive regulation of vasoactive intestinal polypeptide receptor activity in other organism +namespace: biological_process +def: "A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism." [GOC:fj, GOC:jl] +synonym: "positive regulation of VIP receptor activity in other organism" EXACT [] +is_a: GO:0044507 ! positive regulation of receptor activity in other organism +is_a: GO:0044517 ! modulation of vasoactive intestinal polypeptide receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:50:34Z + +[Term] +id: GO:0044519 +name: envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in modulation of VIP receptor activity in other organism" EXACT [] +synonym: "envenomation resulting in regulation of vasoactive intestinal polypeptide receptor activity in other organism" EXACT [] +synonym: "envenomation resulting in regulation of VIP receptor activity in other organism" EXACT [] +is_a: GO:0044511 ! envenomation resulting in modulation of receptor activity in other organism +relationship: has_part GO:0044517 ! modulation of vasoactive intestinal polypeptide receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:53:33Z + +[Term] +id: GO:0044520 +name: envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in positive regulation of VIP receptor activity in other organism" EXACT [] +is_a: GO:0044519 ! envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism +relationship: has_part GO:0044518 ! positive regulation of vasoactive intestinal polypeptide receptor activity in other organism +created_by: jl +creation_date: 2012-02-26T11:55:46Z + +[Term] +id: GO:0044521 +name: envenomation resulting in muscle damage in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism." [GOC:fj, GOC:jl, PMID:10620318, PMID:21150580] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +created_by: jl +creation_date: 2012-02-27T12:31:08Z + +[Term] +id: GO:0044522 +name: envenomation resulting in myocyte killing in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism." [GOC:fj, GOC:jl, PMID:10620318, PMID:21150580] +synonym: "envenomation resulting in myocyte killing causing muscle damage in other organism" EXACT [] +is_a: GO:0044521 ! envenomation resulting in muscle damage in other organism +created_by: jl +creation_date: 2012-02-27T12:33:57Z + +[Term] +id: GO:0044523 +name: envenomation resulting in damage of muscle extracellular matrix in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism." [GOC:fj, GOC:jl, PMID:10620318, PMID:21150580] +synonym: "envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism" EXACT [] +is_a: GO:0044521 ! envenomation resulting in muscle damage in other organism +created_by: jl +creation_date: 2012-02-27T12:40:32Z + +[Term] +id: GO:0044524 +name: protein sulfhydration +namespace: biological_process +def: "The modification of a protein amino acid by the addition of sulfur." [GOC:jl, GOC:jsg, PMID:19903941, PMID:22169477, PMID:8161529] +is_a: GO:0006464 ! cellular protein modification process +created_by: jl +creation_date: 2012-03-15T09:39:33Z + +[Term] +id: GO:0044525 +name: peptidyl-cystine sulfhydration +namespace: biological_process +def: "The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide." [GOC:jl, GOC:jsg] +is_a: GO:0044524 ! protein sulfhydration +created_by: jl +creation_date: 2012-03-15T09:44:07Z + +[Term] +id: GO:0044526 +name: formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine +namespace: biological_process +def: "The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide." [GOC:jl, GOC:jsg] +is_a: GO:0044525 ! peptidyl-cystine sulfhydration +created_by: jl +creation_date: 2012-03-15T09:45:19Z + +[Term] +id: GO:0044527 +name: formation of peptidyl-cystine persulfide by sulphur transfer from H2S +namespace: biological_process +def: "The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide." [GOC:jl, GOC:jsg] +is_a: GO:0044525 ! peptidyl-cystine sulfhydration +created_by: jl +creation_date: 2012-03-15T09:46:23Z + +[Term] +id: GO:0044528 +name: regulation of mitochondrial mRNA stability +namespace: biological_process +def: "Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs." [GOC:al, GOC:jl] +is_a: GO:0043488 ! regulation of mRNA stability +created_by: jl +creation_date: 2012-03-15T03:20:10Z + +[Term] +id: GO:0044529 +name: regulation of mitochondrial rRNA stability +namespace: biological_process +def: "Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs." [GOC:al, GOC:jl] +is_a: GO:0044357 ! regulation of rRNA stability +created_by: jl +creation_date: 2012-03-15T03:22:19Z + +[Term] +id: GO:0044530 +name: supraspliceosomal complex +namespace: cellular_component +def: "Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing." [GOC:ans, GOC:jl, PMID:19282290] +synonym: "supraspliceosome complex" EXACT [] +is_a: GO:0005681 ! spliceosomal complex +created_by: jl +creation_date: 2012-03-15T03:33:08Z + +[Term] +id: GO:0044531 +name: modulation of programmed cell death in other organism +namespace: biological_process +def: "A process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism." [GOC:jl] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:0043067 ! regulation of programmed cell death +created_by: jl +creation_date: 2012-03-20T04:48:41Z + +[Term] +id: GO:0044532 +name: modulation of apoptotic process in other organism +namespace: biological_process +def: "A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism." [GOC:jl] +synonym: "regulation of apoptotic process in other organism" EXACT [] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:0044531 ! modulation of programmed cell death in other organism +created_by: jl +creation_date: 2012-03-21T11:17:18Z + +[Term] +id: GO:0044533 +name: positive regulation of apoptotic process in other organism +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism." [GOC:jl, PMID:17983639] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0044532 ! modulation of apoptotic process in other organism +created_by: jl +creation_date: 2012-03-21T11:25:24Z + +[Term] +id: GO:0044534 +name: envenomation resulting in modulation of apoptotic process in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism." [GOC:fj, GOC:jl, PMID:17983639] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0044532 ! modulation of apoptotic process in other organism +relationship: has_part GO:0044532 ! modulation of apoptotic process in other organism +created_by: jl +creation_date: 2012-03-21T11:39:44Z + +[Term] +id: GO:0044535 +name: very-long-chain fatty acyl-CoA oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide." [PMID:17458872] +synonym: "very long chain fatty-acyl-CoA oxidase activity" EXACT [] +synonym: "very-long-chain acyl-CoA oxidase activity" EXACT [] +synonym: "VLC fatty-acyl-CoA oxidase activity" EXACT [] +xref: EC:1.3.3 +is_a: GO:0003997 ! acyl-CoA oxidase activity +created_by: jl +creation_date: 2012-03-21T02:04:42Z + +[Term] +id: GO:0044536 +name: envenomation resulting in depletion of circulating fibrinogen in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in negative regulation of circulating fibrinogen in other organism" EXACT [] +is_a: GO:0044483 ! envenomation resulting in impairment of hemostasis in other organism +is_a: GO:0061754 ! negative regulation of circulating fibrinogen levels +created_by: jl +creation_date: 2012-03-21T02:56:49Z + +[Term] +id: GO:0044537 +name: regulation of circulating fibrinogen levels +namespace: biological_process +def: "Any process that modulates the quantity of fibrinogen circulating in the bloodstream." [GOC:jl] +is_a: GO:0065008 ! regulation of biological quality +created_by: jl +creation_date: 2012-03-21T03:15:09Z + +[Term] +id: GO:0044538 +name: host cell periphery +namespace: cellular_component +def: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell." [GOC:jl, PMID:20463076] +is_a: GO:0033643 ! host cell part +created_by: jl +creation_date: 2012-03-21T03:26:33Z + +[Term] +id: GO:0044539 +name: long-chain fatty acid import into cell +namespace: biological_process +def: "The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [GOC:jl, GOC:pm, PMID:22022213] +synonym: "long-chain fatty acid import" RELATED [] +synonym: "long-chain fatty acid uptake" EXACT [] +is_a: GO:0015909 ! long-chain fatty acid transport +is_a: GO:0140354 ! lipid import into cell +created_by: jl +creation_date: 2012-03-21T03:34:04Z + +[Term] +id: GO:0044540 +name: L-cystine L-cysteine-lyase (deaminating) +namespace: molecular_function +def: "Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide." [GOC:jl, RHEA:24927] +xref: EC:4.4.1.1 +xref: KEGG_REACTION:R02408 +xref: RHEA:24927 +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: jl +creation_date: 2012-03-22T11:33:32Z + +[Term] +id: GO:0044541 +name: zymogen activation in other organism +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism." [GOC:fj, GOC:jl] +is_a: GO:0031638 ! zymogen activation +is_a: GO:0044033 ! multi-organism metabolic process +created_by: jl +creation_date: 2012-03-22T11:39:41Z + +[Term] +id: GO:0044542 +name: plasminogen activation in other organism +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism." [GOC:fj, GOC:jl] +is_a: GO:0031639 ! plasminogen activation +is_a: GO:0044541 ! zymogen activation in other organism +created_by: jl +creation_date: 2012-03-22T11:40:03Z + +[Term] +id: GO:0044543 +name: envenomation resulting in zymogen activation in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form." [GOC:fj, GOC:jl] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044541 ! zymogen activation in other organism +created_by: jl +creation_date: 2012-03-22T11:52:56Z + +[Term] +id: GO:0044544 +name: envenomation resulting in plasminogen activation in other organism +namespace: biological_process +def: "The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide." [GOC:fj, GOC:jl] +is_a: GO:0044484 ! envenomation resulting in fibrinolysis in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0042730 ! fibrinolysis +intersection_of: has_part GO:0044542 ! plasminogen activation in other organism +relationship: has_part GO:0044542 ! plasminogen activation in other organism +created_by: jl +creation_date: 2012-03-22T11:54:49Z + +[Term] +id: GO:0044545 +name: NSL complex +namespace: cellular_component +def: "A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1." [GOC:lb, PMID:20018852] +synonym: "non-specific lethal complex" EXACT [] +is_a: GO:1902562 ! H4 histone acetyltransferase complex +created_by: jl +creation_date: 2012-03-22T12:49:18Z + +[Term] +id: GO:0044546 +name: NLRP3 inflammasome complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell." [GOC:jl, PMID:21048113] +synonym: "NALP3 inflammasome complex assembly" EXACT [] +synonym: "NLRP3 inflammasome activation" RELATED [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: jl +creation_date: 2012-03-22T01:27:21Z + +[Term] +id: GO:0044547 +name: DNA topoisomerase binding +namespace: molecular_function +alt_id: GO:0017033 +def: "Interacting selectively and non-covalently with a DNA topoisomerase." [GOC:jl] +synonym: "DNA topoisomerase I binding" NARROW [] +is_a: GO:0019899 ! enzyme binding +created_by: jl +creation_date: 2012-03-22T02:30:37Z + +[Term] +id: GO:0044548 +name: S100 protein binding +namespace: molecular_function +alt_id: GO:0048154 +alt_id: GO:0048155 +def: "Interacting selectively and non-covalently with a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jid] +synonym: "S100 alpha binding" NARROW [] +synonym: "S100 beta binding" NARROW [] +synonym: "S100 binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: jl +creation_date: 2012-03-22T03:23:51Z + +[Term] +id: GO:0044549 +name: GTP cyclohydrolase binding +namespace: molecular_function +alt_id: GO:0043106 +def: "Interacting selectively and non-covalently with a GTP cyclohydrolase." [GOC:jl] +synonym: "GTP cyclohydrolase I binding" NARROW [] +is_a: GO:0019899 ! enzyme binding +created_by: jl +creation_date: 2012-03-22T04:38:14Z + +[Term] +id: GO:0044550 +name: secondary metabolite biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] +synonym: "secondary metabolite biosynthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0019748 ! secondary metabolic process +created_by: jl +creation_date: 2012-03-29T01:55:18Z + +[Term] +id: GO:0044551 +name: envenomation resulting in vasodilation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism." [GOC:ecd, GOC:jl, PMID:21050868] +synonym: "envenomation resulting in modulation of vasodilation in other organism" RELATED [] +synonym: "envenomation resulting in regulation of vasodilation in other organism" RELATED [] +is_a: GO:0044500 ! envenomation resulting in negative regulation of blood pressure in other organism +relationship: has_part GO:0044552 ! vasodilation in other organism +created_by: jl +creation_date: 2012-03-29T02:07:45Z + +[Term] +id: GO:0044552 +name: vasodilation in other organism +namespace: biological_process +def: "A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism." [GOC:ecd, GOC:jl, PMID:21050868] +synonym: "modulation of vasodilation in other organism" RELATED [] +synonym: "regulation of vasodilation in other organism" RELATED [] +is_a: GO:0042311 ! vasodilation +is_a: GO:0044553 ! modulation of biological quality in other organism +created_by: jl +creation_date: 2012-03-29T02:14:42Z + +[Term] +id: GO:0044553 +name: modulation of biological quality in other organism +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:jl] +synonym: "regulation of biological quality in other organism" EXACT [] +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2012-03-29T02:35:03Z + +[Term] +id: GO:0044554 +name: modulation of heart rate in other organism +namespace: biological_process +def: "Any process that modulates the frequency or rate of heart contraction of another organism." [GOC:jl, PMID:20923766] +synonym: "regulation of heart rate in other organism" EXACT [] +is_a: GO:0002027 ! regulation of heart rate +is_a: GO:0044553 ! modulation of biological quality in other organism +created_by: jl +creation_date: 2012-03-29T02:59:43Z + +[Term] +id: GO:0044555 +name: negative regulation of heart rate in other organism +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency of heart contraction of another organism." [GOC:ecd, GOC:jl, PMID:20923766] +is_a: GO:0010459 ! negative regulation of heart rate +is_a: GO:0044554 ! modulation of heart rate in other organism +created_by: jl +creation_date: 2012-03-29T03:01:20Z + +[Term] +id: GO:0044556 +name: envenomation resulting in negative regulation of heart rate of other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism." [GOC:ecd, GOC:jl, PMID:20923766] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044555 ! negative regulation of heart rate in other organism +created_by: jl +creation_date: 2012-03-29T03:04:52Z + +[Term] +id: GO:0044557 +name: relaxation of smooth muscle +namespace: biological_process +def: "A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:jl] +synonym: "smooth muscle relaxation" EXACT [] +is_a: GO:0090075 ! relaxation of muscle +created_by: jl +creation_date: 2012-04-05T02:42:28Z + +[Term] +id: GO:0044558 +name: uterine smooth muscle relaxation +namespace: biological_process +def: "A process in which the extent of smooth muscle contraction is reduced in the uterus." [GOC:jl] +synonym: "smooth muscle relaxation of the uterus" EXACT [] +is_a: GO:0044557 ! relaxation of smooth muscle +created_by: jl +creation_date: 2012-04-05T02:57:11Z + +[Term] +id: GO:0044559 +name: envenomation resulting in modulation of voltage-gated potassium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism." [GOC:fj, GOC:jl] +is_a: GO:0044560 ! envenomation resulting in modulation of ion channel activity in other organism +relationship: has_part GO:0044360 ! modulation of voltage-gated potassium channel activity in other organism +created_by: jl +creation_date: 2012-04-05T03:35:20Z + +[Term] +id: GO:0044560 +name: envenomation resulting in modulation of ion channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism." [GOC:fj, GOC:jl] +synonym: "envenomation resulting in regulation of ion channel activity in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044561 ! modulation of ion channel activity in other organism +created_by: jl +creation_date: 2012-04-05T03:46:35Z + +[Term] +id: GO:0044561 +name: modulation of ion channel activity in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism." [GOC:jl] +synonym: "regulation of ion channel activity in other organism" EXACT [] +is_a: GO:0044359 ! modulation of molecular function in other organism +created_by: jl +creation_date: 2012-04-05T03:48:28Z + +[Term] +id: GO:0044562 +name: envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism." [GOC:fj, GOC:jl] +is_a: GO:0044559 ! envenomation resulting in modulation of voltage-gated potassium channel activity in other organism +relationship: has_part GO:0044361 ! negative regulation of voltage-gated potassium channel activity in other organism +created_by: jl +creation_date: 2012-04-05T04:01:49Z + +[Term] +id: GO:0044563 +name: envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism." [GOC:fj, GOC:jl] +synonym: "voltage-dependence of activation shift (to the left)" EXACT [] +is_a: GO:0044562 ! envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism +created_by: jl +creation_date: 2012-04-05T04:06:29Z + +[Term] +id: GO:0044564 +name: envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism." [GOC:fj, GOC:jl] +is_a: GO:0044562 ! envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism +created_by: jl +creation_date: 2012-04-05T04:14:24Z + +[Term] +id: GO:0044565 +name: dendritic cell proliferation +namespace: biological_process +def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816] +is_a: GO:0046651 ! lymphocyte proliferation +created_by: jl +creation_date: 2012-04-05T04:31:39Z + +[Term] +id: GO:0044566 +name: chondrocyte activation +namespace: biological_process +def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl] +is_a: GO:0001775 ! cell activation +created_by: jl +creation_date: 2012-04-05T04:45:38Z + +[Term] +id: GO:0044567 +name: primary cell wall cellulose synthase complex +namespace: cellular_component +def: "A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein." [GOC:mengo_curators, GOC:tt, PMID:17878302, PMID:21307367] +synonym: "primary cell wall CESA complex" EXACT [] +synonym: "primary cell-wall cellulose synthase complex" EXACT [] +is_a: GO:0010330 ! cellulose synthase complex +created_by: jl +creation_date: 2012-04-18T12:24:16Z + +[Term] +id: GO:0044568 +name: secondary cell wall cellulose synthase complex +namespace: cellular_component +def: "A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4." [GOC:mengo_curators, GOC:tt, PMID:21307367] +synonym: "secondary cell wall CESA complex" EXACT [] +synonym: "secondary cell wall CesA complex" EXACT [] +synonym: "secondary cell-wall cellulose synthase complex" EXACT [] +is_a: GO:0010330 ! cellulose synthase complex +created_by: jl +creation_date: 2012-04-18T12:55:04Z + +[Term] +id: GO:0044569 +name: [Ni-Fe] hydrogenase complex +namespace: cellular_component +def: "A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer." [GOC:mengo_curators, GOC:tt, PMID:8936309] +synonym: "Ni-Fe hydrogenase complex" EXACT [] +synonym: "nickel-iron hydrogenase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +created_by: jl +creation_date: 2012-04-18T01:26:35Z + +[Term] +id: GO:0044570 +name: starch utilization system complex +namespace: cellular_component +def: "A bacterial cell envelope-associated multiprotein system, which binds and degrades starch." [GOC:mengo_curators, GOC:tt, PMID:19553672] +synonym: "Sus complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0009279 ! cell outer membrane +created_by: jl +creation_date: 2012-04-18T02:46:24Z + +[Term] +id: GO:0044571 +name: [2Fe-2S] cluster assembly +namespace: biological_process +def: "The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster." [GOC:jl, GOC:mengo_curators, GOC:pde, GOC:tt, GOC:vw, PMID:15952888] +synonym: "2Fe-2S cluster assembly" EXACT [] +synonym: "[2Fe-2S] cluster biosynthetic process" RELATED [] +is_a: GO:0016226 ! iron-sulfur cluster assembly +created_by: jl +creation_date: 2012-04-18T03:06:30Z + +[Term] +id: GO:0044572 +name: [4Fe-4S] cluster assembly +namespace: biological_process +def: "The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster." [GOC:jl, GOC:mengo_curators, GOC:pde, GOC:tt, GOC:vw, PMID:15952888] +synonym: "4Fe-4S cluster assembly" EXACT [] +synonym: "[4Fe-4S] cluster biosynthetic process" RELATED [] +is_a: GO:0016226 ! iron-sulfur cluster assembly +created_by: jl +creation_date: 2012-04-18T03:19:23Z + +[Term] +id: GO:0044573 +name: nitrogenase P cluster assembly +namespace: biological_process +def: "The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide." [PMID:17563349] +synonym: "nitrogenase P cluster biosynthesis" EXACT [] +synonym: "nitrogenase P cluster maturation" EXACT [] +is_a: GO:0016226 ! iron-sulfur cluster assembly +created_by: jl +creation_date: 2012-04-18T03:29:04Z + +[Term] +id: GO:0044574 +name: starch utilization system complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan." [GOC:mengo_curators, GOC:tt, PMID:19553672, PMID:21219452] +synonym: "assembly of starch utilization system complex" EXACT [] +synonym: "SUS complex assembly" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: jl +creation_date: 2012-04-19T03:40:24Z + +[Term] +id: GO:0044575 +name: cellulosome assembly +namespace: biological_process +def: "The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall." [GOC:mengo_curators, GOC:tt, PMID:20373916] +is_a: GO:0070925 ! organelle assembly +created_by: jl +creation_date: 2012-04-19T03:42:36Z + +[Term] +id: GO:0044576 +name: pentose catabolic process to ethanol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol." [GOC:mengo_curators, GOC:tt] +synonym: "pentose catabolism to ethanol" EXACT [] +is_a: GO:0006115 ! ethanol biosynthetic process +is_a: GO:0019323 ! pentose catabolic process +created_by: jl +creation_date: 2012-04-19T03:46:37Z + +[Term] +id: GO:0044577 +name: xylose catabolic process to ethanol +namespace: biological_process +def: "The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol." [GOC:mengo_curators, GOC:tt] +synonym: "xylose catabolism to ethanol" EXACT [] +is_a: GO:0042843 ! D-xylose catabolic process +is_a: GO:0044576 ! pentose catabolic process to ethanol +created_by: jl +creation_date: 2012-04-19T03:50:46Z + +[Term] +id: GO:0044578 +name: butyryl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathway resulting in the formation of butyryl-CoA." [GOC:jl] +synonym: "butyryl-CoA biosynthesis" EXACT [] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +created_by: jl +creation_date: 2012-04-19T04:23:26Z + +[Term] +id: GO:0044579 +name: butyryl-CoA biosynthetic process from acetyl-CoA +namespace: biological_process +def: "The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA." [GOC:mengo_curators, GOC:tt, PMID:19539744] +synonym: "butyryl-CoA biosynthesis from acetyl-CoA" EXACT [] +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0044578 ! butyryl-CoA biosynthetic process +created_by: jl +creation_date: 2012-04-19T04:25:07Z + +[Term] +id: GO:0044580 +name: butyryl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA." [GOC:jl] +synonym: "butyryl-CoA catabolism" EXACT [] +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +created_by: jl +creation_date: 2012-04-19T04:28:46Z + +[Term] +id: GO:0044581 +name: butyryl-CoA catabolic process to butyrate +namespace: biological_process +def: "The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate." [GOC:mengo_curators, GOC:tt, PMID:19539744] +synonym: "butyryl-CoA catabolism to butyrate" EXACT [] +is_a: GO:0044580 ! butyryl-CoA catabolic process +is_a: GO:0046358 ! butyrate biosynthetic process +created_by: jl +creation_date: 2012-04-19T04:29:40Z + +[Term] +id: GO:0044582 +name: butyryl-CoA catabolic process to butanol +namespace: biological_process +def: "The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol." [GOC:mengo_curators, GOC:tt, PMID:19539744] +synonym: "butyryl-CoA catabolism to butanol" EXACT [] +is_a: GO:0044580 ! butyryl-CoA catabolic process +is_a: GO:0071271 ! 1-butanol biosynthetic process +created_by: jl +creation_date: 2012-04-19T04:40:06Z + +[Term] +id: GO:0044583 +name: cellotriose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellotriose." [GOC:mengo_curators, GOC:tt] +is_a: GO:0048031 ! trisaccharide binding +created_by: jl +creation_date: 2012-04-24T04:48:01Z + +[Term] +id: GO:0044584 +name: cellodextrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellodextrin, a glucose polymer of 2 or more glucose monomers." [GOC:mengo_curators, GOC:tt, PMID:18952792] +is_a: GO:0030247 ! polysaccharide binding +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2012-04-24T04:52:05Z + +[Term] +id: GO:0044585 +name: cellobiose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellobiose, a disaccharide that represents the basic repeating unit of cellulose." [GOC:mengo_curators, GOC:tt] +is_a: GO:0048030 ! disaccharide binding +created_by: jl +creation_date: 2012-04-24T04:55:10Z + +[Term] +id: GO:0044586 +name: cellotetraose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose." [GOC:mengo_curators, GOC:tt] +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2012-04-24T04:56:10Z + +[Term] +id: GO:0044587 +name: cellopentaose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose." [GOC:mengo_curators, GOC:tt] +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2012-04-24T04:57:01Z + +[Term] +id: GO:0044588 +name: laminaribiose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with laminaribiose, a disaccharide." [GOC:mengo_curators, GOC:tt] +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2012-04-26T01:19:40Z + +[Term] +id: GO:0044589 +name: pectin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pectin." [GOC:mengo_curators, GOC:tt] +is_a: GO:0008144 ! drug binding +is_a: GO:0048028 ! galacturonan binding +created_by: jl +creation_date: 2012-04-26T01:26:56Z + +[Term] +id: GO:0044590 +name: iron-sulfur-molybdenum cofactor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase." [GOC:mengo_curators, GOC:tt, PMID:18429691] +synonym: "FeMo co binding" EXACT [] +synonym: "FeMoco binding" EXACT [] +is_a: GO:0048037 ! cofactor binding +created_by: jl +creation_date: 2012-04-26T02:27:39Z + +[Term] +id: GO:0044591 +name: response to amylopectin +namespace: biological_process +def: "A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus." [GOC:mengo_curators, GOC:tt] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: jl +creation_date: 2012-04-26T03:20:03Z + +[Term] +id: GO:0044592 +name: response to pullulan +namespace: biological_process +def: "A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus." [GOC:mengo_curators, GOC:tt] +is_a: GO:0009743 ! response to carbohydrate +created_by: jl +creation_date: 2012-04-26T03:59:06Z + +[Term] +id: GO:0044593 +name: iron-sulfur-molybdenum cofactor assembly +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase." [GOC:mengo_curators, GOC:tt, PMID:18429691] +synonym: "FeMoco assembly" EXACT [] +synonym: "FeMoco biosynthetic process" EXACT [] +synonym: "iron molybdenum cofactor assembly" EXACT [] +synonym: "iron molybdenum cofactor biosynthesis" EXACT [] +synonym: "iron molybdenum cofactor biosynthetic process" EXACT [] +is_a: GO:0051188 ! cofactor biosynthetic process +created_by: jl +creation_date: 2012-04-26T04:01:53Z + +[Term] +id: GO:0044594 +name: 17-beta-hydroxysteroid dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+." [PMID:17074428] +xref: RHEA:24612 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: jl +creation_date: 2012-04-26T04:49:13Z + +[Term] +id: GO:0044595 +name: decaprenyldihydroxybenzoate methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate." [PMID:10777520] +xref: MetaCyc:RXN-9282 +xref: Reactome:R-HSA-2162193 "DHDB is methylated to MHDB by COQ3" +xref: RHEA:44492 +is_a: GO:0010420 ! 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity +created_by: jl +creation_date: 2012-04-26T04:52:05Z + +[Term] +id: GO:0044596 +name: 3-demethylubiquinol-10 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10." [PMID:10777520] +xref: MetaCyc:RXN-9237 +xref: Reactome:R-HSA-2162186 "DeMQ10H2 is methylated to Q10H2 by COQ3" +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +is_a: GO:0061542 ! 3-demethylubiquinol-n 3-O-methyltransferase activity +created_by: jl +creation_date: 2012-04-26T04:54:11Z + +[Term] +id: GO:0044597 +name: daunorubicin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer." [PMID:20837989] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: jl +creation_date: 2012-05-01T03:09:51Z + +[Term] +id: GO:0044598 +name: doxorubicin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy." [PMID:10200167] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901661 ! quinone metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: jl +creation_date: 2012-05-01T03:30:21Z + +[Term] +id: GO:0044599 +name: AP-5 adaptor complex +namespace: cellular_component +def: "An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo." [PMID:22022230] +synonym: "adaptor protein-5 adaptor complex" EXACT [] +is_a: GO:0030119 ! AP-type membrane coat adaptor complex +created_by: jl +creation_date: 2012-05-01T03:48:11Z + +[Term] +id: GO:0044600 +name: protein guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins." [GOC:sp, PMID:20651120] +is_a: GO:0070568 ! guanylyltransferase activity +relationship: part_of GO:0018260 ! protein guanylylation +created_by: jl +creation_date: 2012-05-01T04:00:34Z + +[Term] +id: GO:0044601 +name: protein denucleotidylation +namespace: biological_process +def: "The removal of a nucleotide from a protein amino acid." [GOC:sp, PMID:21734656] +is_a: GO:0006464 ! cellular protein modification process +created_by: jl +creation_date: 2012-05-01T04:13:54Z + +[Term] +id: GO:0044602 +name: protein deadenylylation +namespace: biological_process +def: "The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid." [GOC:sp, PMID:21734656] +synonym: "protein deAMPylation" EXACT [PMID:21734656] +is_a: GO:0044601 ! protein denucleotidylation +created_by: jl +creation_date: 2012-05-01T04:16:22Z + +[Term] +id: GO:0044603 +name: protein adenylylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins." [PMID:21734656] +synonym: "protein deAMPylase activity" EXACT [PMID:21734656] +synonym: "protein deAMPylation activity" EXACT [PMID:21734656] +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0018117 ! protein adenylylation +relationship: part_of GO:0044602 ! protein deadenylylation +created_by: jl +creation_date: 2012-05-01T04:18:07Z + +[Term] +id: GO:0044604 +name: ATPase-coupled phytochelatin transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0071991 +alt_id: GO:0071992 +def: "Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." [GOC:mah, ISBN:0198506732] +synonym: "ATP-dependent phytochelatin transmembrane transporter activity" EXACT [] +synonym: "cadystin transmembrane transporter activity" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "cadystin transmembrane transporter ATPase activity" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "cadystin transporter activity" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "phytochelatin transmembrane transporter activity" RELATED [] +synonym: "phytochelatin transmembrane transporter ATPase activity" EXACT [] +synonym: "phytochelatin transporter activity" RELATED [] +is_a: GO:0015440 ! ATPase-coupled peptide transmembrane transporter activity +relationship: part_of GO:0071994 ! phytochelatin transmembrane transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14492 xsd:anyURI +created_by: jl +creation_date: 2010-10-25T01:00:17Z + +[Term] +id: GO:0044605 +name: phosphocholine transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate." [GOC:sp, PMID:21822290] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +created_by: jl +creation_date: 2012-05-24T04:44:25Z + +[Term] +id: GO:0044606 +name: phosphocholine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate." [GOC:sp, PMID:22158903] +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides +created_by: jl +creation_date: 2012-05-24T04:46:44Z + +[Term] +id: GO:0044607 +name: obsolete disruption by symbiont of host endothelial cells +namespace: biological_process +def: "OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells." [GOC:jl] +comment: This term was obsoleted because the cell type should be captured as an annotation extension. +is_obsolete: true +created_by: jl +creation_date: 2012-05-30T02:24:50Z + +[Term] +id: GO:0044608 +name: peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine +namespace: biological_process +def: "The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester." [RESID:AA0507] +synonym: "peptidyl-threonine esterification" EXACT [] +xref: RESID:AA0507 +is_a: GO:0006481 ! C-terminal protein methylation +is_a: GO:0018350 ! protein esterification +created_by: jl +creation_date: 2012-05-30T02:47:57Z + +[Term] +id: GO:0044609 +name: DBIRD complex +namespace: cellular_component +def: "A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD." [GOC:sp, PMID:22446626] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: jl +creation_date: 2012-05-30T03:04:23Z + +[Term] +id: GO:0044610 +name: FMN transmembrane transporter activity +namespace: molecular_function +def: "Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other." [GOC:ans, PMID:22185573] +synonym: "flavine mononucleotide transmembrane transporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +created_by: jl +creation_date: 2012-05-30T03:09:19Z + +[Term] +id: GO:0044611 +name: nuclear pore inner ring +namespace: cellular_component +def: "A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "Nup170 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: jl +creation_date: 2012-06-20T01:14:17Z + +[Term] +id: GO:0044612 +name: nuclear pore linkers +namespace: cellular_component +def: "A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p)." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "Nic96 complex" RELATED [] +synonym: "Nup82 complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: jl +creation_date: 2012-06-20T01:22:40Z + +[Term] +id: GO:0044613 +name: nuclear pore central transport channel +namespace: cellular_component +def: "The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "karyopherin docking complex" RELATED [] +synonym: "nuclear pore central channel" EXACT [] +synonym: "nuclear pore central plug" EXACT [] +synonym: "nuclear pore transport channel" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: jl +creation_date: 2012-06-20T01:25:30Z + +[Term] +id: GO:0044614 +name: nuclear pore cytoplasmic filaments +namespace: cellular_component +def: "Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "cytoplasmic fibers of the NPC" EXACT [PMID:7775481, PMID:8978815, PMID:9456312] +synonym: "cytoplasmic fibers of the nuclear pore complex" EXACT [PMID:7775481, PMID:8978815, PMID:9456312] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: jl +creation_date: 2012-06-20T01:28:18Z + +[Term] +id: GO:0044615 +name: nuclear pore nuclear basket +namespace: cellular_component +def: "A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: jl +creation_date: 2012-06-20T01:31:01Z + +[Term] +id: GO:0044616 +name: modulation of relaxation of muscle in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the relaxation of muscle in a second organism." [GOC:jl] +synonym: "regulation of relaxation of muscle in other organism" EXACT [] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:1901077 ! regulation of relaxation of muscle +created_by: jl +creation_date: 2012-07-04T01:54:12Z + +[Term] +id: GO:0044617 +name: modulation of relaxation of smooth muscle in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the relaxation of smooth muscle in a second organism." [GOC:jl] +synonym: "regulation of relaxation of smooth muscle in other organism" EXACT [] +is_a: GO:0044616 ! modulation of relaxation of muscle in other organism +is_a: GO:1901080 ! regulation of relaxation of smooth muscle +created_by: jl +creation_date: 2012-07-04T01:55:37Z + +[Term] +id: GO:0044618 +name: modulation of relaxation of uterine smooth muscle in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism." [GOC:jl] +synonym: "regulation of relaxation of uterine smooth muscle in other organism" EXACT [] +is_a: GO:0044617 ! modulation of relaxation of smooth muscle in other organism +is_a: GO:1900719 ! regulation of uterine smooth muscle relaxation +created_by: jl +creation_date: 2012-07-04T01:56:04Z + +[Term] +id: GO:0044619 +name: positive regulation of relaxation of uterine smooth muscle in other organism +namespace: biological_process +def: "The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism." [GOC:jl] +is_a: GO:0044618 ! modulation of relaxation of uterine smooth muscle in other organism +is_a: GO:1900721 ! positive regulation of uterine smooth muscle relaxation +created_by: jl +creation_date: 2012-07-04T02:51:26Z + +[Term] +id: GO:0044620 +name: ACP phosphopantetheine attachment site binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP)." [GOC:jl, GOC:vw] +is_a: GO:0051192 ! prosthetic group binding +created_by: jl +creation_date: 2012-07-04T03:25:04Z + +[Term] +id: GO:0044621 +name: modulation of cell migration in other organism +namespace: biological_process +def: "The process in which an organism effects a change in the process of cell migration in a second organism." [GOC:jl] +synonym: "regulation of cell migration in other organism" EXACT [] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0035821 ! modulation of process of other organism +created_by: jl +creation_date: 2012-07-04T04:40:13Z + +[Term] +id: GO:0044622 +name: negative regulation of cell migration in other organism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism." [GOC:jl] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0044621 ! modulation of cell migration in other organism +created_by: jl +creation_date: 2012-07-04T04:42:14Z + +[Term] +id: GO:0044623 +name: positive regulation of cell migration in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell migration in a second organism." [GOC:jl] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0044621 ! modulation of cell migration in other organism +created_by: jl +creation_date: 2012-07-04T04:44:59Z + +[Term] +id: GO:0044624 +name: envenomation resulting in modulation of cell migration in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism." [GOC:jl, PMID:19932752] +synonym: "envenomation resulting in regulation of cell migration in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0044621 ! modulation of cell migration in other organism +relationship: has_part GO:0044621 ! modulation of cell migration in other organism +created_by: jl +creation_date: 2012-07-04T05:03:56Z + +[Term] +id: GO:0044625 +name: envenomation resulting in negative regulation of cell migration in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism." [GOC:jl, PMID:19932752] +is_a: GO:0044624 ! envenomation resulting in modulation of cell migration in other organism +relationship: has_part GO:0044622 ! negative regulation of cell migration in other organism +created_by: jl +creation_date: 2012-07-04T05:07:16Z + +[Term] +id: GO:0044626 +name: envenomation resulting in positive regulation of cell migration in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism." [GOC:jl, PMID:19932752] +is_a: GO:0044624 ! envenomation resulting in modulation of cell migration in other organism +relationship: has_part GO:0044623 ! positive regulation of cell migration in other organism +created_by: jl +creation_date: 2012-07-04T05:08:21Z + +[Term] +id: GO:0044627 +name: modulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism." [GOC:jl, PMID:20837040] +synonym: "regulation of complement activation, classical pathway in other organism" EXACT [] +is_a: GO:0030450 ! regulation of complement activation, classical pathway +is_a: GO:0044645 ! modulation of complement activation in other organism +created_by: jl +creation_date: 2012-07-05T12:55:53Z + +[Term] +id: GO:0044628 +name: positive regulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0044627 ! modulation of complement activation, classical pathway in other organism +is_a: GO:0045960 ! positive regulation of complement activation, classical pathway +created_by: jl +creation_date: 2012-07-05T01:00:10Z + +[Term] +id: GO:0044629 +name: negative regulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0044627 ! modulation of complement activation, classical pathway in other organism +is_a: GO:0045959 ! negative regulation of complement activation, classical pathway +created_by: jl +creation_date: 2012-07-05T01:03:25Z + +[Term] +id: GO:0044630 +name: modulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism." [GOC:jl, PMID:20837040] +synonym: "regulation of complement activation, lectin pathway in other organism" EXACT [] +is_a: GO:0001868 ! regulation of complement activation, lectin pathway +is_a: GO:0044645 ! modulation of complement activation in other organism +created_by: jl +creation_date: 2012-07-05T01:10:31Z + +[Term] +id: GO:0044631 +name: positive regulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0001870 ! positive regulation of complement activation, lectin pathway +is_a: GO:0044630 ! modulation of complement activation, lectin pathway in other organism +created_by: jl +creation_date: 2012-07-05T01:17:33Z + +[Term] +id: GO:0044632 +name: negative regulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0001869 ! negative regulation of complement activation, lectin pathway +is_a: GO:0044630 ! modulation of complement activation, lectin pathway in other organism +created_by: jl +creation_date: 2012-07-05T01:18:43Z + +[Term] +id: GO:0044633 +name: modulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism." [GOC:jl, PMID:20837040] +synonym: "regulation of complement activation, alternative pathway in other organism" RELATED [] +is_a: GO:0030451 ! regulation of complement activation, alternative pathway +is_a: GO:0044645 ! modulation of complement activation in other organism +created_by: jl +creation_date: 2012-07-05T04:24:08Z + +[Term] +id: GO:0044634 +name: negative regulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0044633 ! modulation of complement activation, alternative pathway in other organism +is_a: GO:0045957 ! negative regulation of complement activation, alternative pathway +created_by: jl +creation_date: 2012-07-05T04:32:55Z + +[Term] +id: GO:0044635 +name: positive regulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism." [GOC:jl, PMID:20837040] +is_a: GO:0044633 ! modulation of complement activation, alternative pathway in other organism +is_a: GO:0045958 ! positive regulation of complement activation, alternative pathway +created_by: jl +creation_date: 2012-07-05T04:36:11Z + +[Term] +id: GO:0044636 +name: envenomation resulting in modulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044646 ! envenomation resulting in modulation of complement activation in other organism +relationship: has_part GO:0044627 ! modulation of complement activation, classical pathway in other organism +created_by: jl +creation_date: 2012-07-05T04:40:57Z + +[Term] +id: GO:0044637 +name: envenomation resulting in negative regulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044636 ! envenomation resulting in modulation of complement activation, classical pathway in other organism +relationship: has_part GO:0044629 ! negative regulation of complement activation, classical pathway in other organism +created_by: jl +creation_date: 2012-07-05T04:46:56Z + +[Term] +id: GO:0044638 +name: envenomation resulting in positive regulation of complement activation, classical pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044636 ! envenomation resulting in modulation of complement activation, classical pathway in other organism +relationship: has_part GO:0044628 ! positive regulation of complement activation, classical pathway in other organism +created_by: jl +creation_date: 2012-07-05T04:51:36Z + +[Term] +id: GO:0044639 +name: envenomation resulting in modulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +synonym: "envenomation resulting in regulation of complement activation, lectin pathway in other organism" EXACT [] +is_a: GO:0044646 ! envenomation resulting in modulation of complement activation in other organism +relationship: has_part GO:0044630 ! modulation of complement activation, lectin pathway in other organism +created_by: jl +creation_date: 2012-07-05T04:53:36Z + +[Term] +id: GO:0044640 +name: envenomation resulting in negative regulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044639 ! envenomation resulting in modulation of complement activation, lectin pathway in other organism +relationship: has_part GO:0044632 ! negative regulation of complement activation, lectin pathway in other organism +created_by: jl +creation_date: 2012-07-05T04:56:30Z + +[Term] +id: GO:0044641 +name: envenomation resulting in positive regulation of complement activation, lectin pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044639 ! envenomation resulting in modulation of complement activation, lectin pathway in other organism +relationship: has_part GO:0044631 ! positive regulation of complement activation, lectin pathway in other organism +created_by: jl +creation_date: 2012-07-11T11:50:23Z + +[Term] +id: GO:0044642 +name: envenomation resulting in modulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +synonym: "envenomation resulting in regulation of complement activation, alternative pathway in other organism" EXACT [] +is_a: GO:0044646 ! envenomation resulting in modulation of complement activation in other organism +relationship: has_part GO:0044633 ! modulation of complement activation, alternative pathway in other organism +created_by: jl +creation_date: 2012-07-11T11:53:12Z + +[Term] +id: GO:0044643 +name: envenomation resulting in positive regulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044642 ! envenomation resulting in modulation of complement activation, alternative pathway in other organism +relationship: has_part GO:0044635 ! positive regulation of complement activation, alternative pathway in other organism +created_by: jl +creation_date: 2012-07-11T11:56:48Z + +[Term] +id: GO:0044644 +name: envenomation resulting in negative regulation of complement activation, alternative pathway in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +is_a: GO:0044642 ! envenomation resulting in modulation of complement activation, alternative pathway in other organism +relationship: has_part GO:0044634 ! negative regulation of complement activation, alternative pathway in other organism +created_by: jl +creation_date: 2012-07-11T12:35:11Z + +[Term] +id: GO:0044645 +name: modulation of complement activation in other organism +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of complement activation in a different organism." [GOC:fj, GOC:jl, PMID:20837040] +synonym: "regulation of complement activation in other organism" EXACT [] +is_a: GO:0035821 ! modulation of process of other organism +is_a: GO:0045088 ! regulation of innate immune response +created_by: jl +creation_date: 2012-07-11T12:37:50Z + +[Term] +id: GO:0044646 +name: envenomation resulting in modulation of complement activation in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism." [GOC:fj, GOC:jl, PMID:20837040] +synonym: "envenomation resulting in regulation of complement activation in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044645 ! modulation of complement activation in other organism +created_by: jl +creation_date: 2012-07-11T12:49:28Z + +[Term] +id: GO:0044647 +name: host-symbiont bicellular tight junction +namespace: cellular_component +def: "An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane." [GOC:jl, PMID:21803641] +synonym: "host-parasite tight junction" EXACT [] +synonym: "host-pathogen tight junction" EXACT [] +is_a: GO:0005923 ! bicellular tight junction +created_by: jl +creation_date: 2012-07-11T12:56:18Z + +[Term] +id: GO:0044648 +name: histone H3-K4 dimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone." [GOC:jl, PMID:21875999] +is_a: GO:0018027 ! peptidyl-lysine dimethylation +is_a: GO:0051568 ! histone H3-K4 methylation +created_by: jl +creation_date: 2012-07-11T01:27:33Z + +[Term] +id: GO:0044649 +name: envenomation resulting in cytolysis in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism." [GOC:fj, GOC:jl, PMID:22484288] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: GO:0035738 ! envenomation resulting in modulation of process in other organism +intersection_of: has_part GO:0051715 ! cytolysis in other organism +relationship: has_part GO:0051715 ! cytolysis in other organism +created_by: jl +creation_date: 2012-07-11T02:13:38Z + +[Term] +id: GO:0044650 +name: adhesion of symbiont to host cell +namespace: biological_process +def: "The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly." [GOC:jl] +is_a: GO:0044406 ! adhesion of symbiont to host +created_by: jl +creation_date: 2012-07-12T12:42:14Z + +[Term] +id: GO:0044651 +name: adhesion of symbiont to host epithelial cell +namespace: biological_process +def: "The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly." [GOC:jl, PMID:10066176] +is_a: GO:0044650 ! adhesion of symbiont to host cell +created_by: jl +creation_date: 2012-07-12T12:47:09Z + +[Term] +id: GO:0044652 +name: adhesion of symbiont to host endothelial cell +namespace: biological_process +def: "The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly." [GOC:jl, PMID:10066176] +is_a: GO:0044650 ! adhesion of symbiont to host cell +created_by: jl +creation_date: 2012-07-12T12:49:07Z + +[Term] +id: GO:0044653 +name: dextrin alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: dextrin + H2O = alpha-D-glucose." [PMID:18556189] +xref: EC:3.2.1 +is_a: GO:0090599 ! alpha-glucosidase activity +created_by: jl +creation_date: 2012-07-23T02:01:12Z + +[Term] +id: GO:0044654 +name: starch alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: starch + H2O = alpha-D-glucose." [PMID:18556189] +xref: EC:3.2.1 +is_a: GO:0090599 ! alpha-glucosidase activity +created_by: jl +creation_date: 2012-07-23T02:08:10Z + +[Term] +id: GO:0044655 +name: phagosome reneutralization +namespace: biological_process +def: "Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation." [GOC:rjd, PMID:22008230] +synonym: "phagosomal reneutralization" EXACT [] +synonym: "phagosome pH elevation" EXACT [] +is_a: GO:0051454 ! intracellular pH elevation +relationship: part_of GO:0090382 ! phagosome maturation +created_by: jl +creation_date: 2012-07-26T04:21:14Z + +[Term] +id: GO:0044656 +name: regulation of post-lysosomal vacuole size +namespace: biological_process +def: "Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis." [GOC:rjd, PMID:22008230] +synonym: "regulation of post-lysosome size" EXACT [GOC:dph] +is_a: GO:0032535 ! regulation of cellular component size +created_by: jl +creation_date: 2012-07-26T04:30:56Z + +[Term] +id: GO:0044657 +name: pore formation in membrane of other organism during symbiotic interaction +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction." [GOC:jl] +is_a: GO:0035915 ! pore formation in membrane of other organism +is_a: GO:0052025 ! modification by symbiont of host cell membrane +created_by: jl +creation_date: 2012-08-01T13:12:10Z + +[Term] +id: GO:0044658 +name: pore formation in membrane of host by symbiont +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism." [GOC:jl] +is_a: GO:0044657 ! pore formation in membrane of other organism during symbiotic interaction +created_by: jl +creation_date: 2012-08-01T13:14:42Z + +[Term] +id: GO:0044659 +name: viral release from host cell by cytolysis +namespace: biological_process +alt_id: GO:0019077 +alt_id: GO:0046756 +def: "The killing by a virus of a cell by means of the rupture of cell membranes and the loss of cytoplasm." [GOC:jl, PMID:26728778] +synonym: "cytolysis by virus of host cell" RELATED [] +synonym: "lytic viral life cycle" RELATED [] +synonym: "lytic viral release" EXACT [] +synonym: "viral exit from host cell by cytolysis" EXACT [] +synonym: "viral release by cell lysis" EXACT [] +synonym: "viral release by host cell lysis" EXACT [] +xref: VZ:1077 "Cell lysis" +is_a: GO:0019076 ! viral release from host cell +is_a: GO:0039633 ! killing by virus of host cell +relationship: has_part GO:0001897 ! cytolysis by symbiont of host cells +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18852 xsd:anyURI +created_by: jl +creation_date: 2012-08-01T13:16:39Z + +[Term] +id: GO:0044660 +name: viral release by cytolysis via pore formation in host cell membrane +namespace: biological_process +def: "The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane." [GOC:jl] +synonym: "cytolysis by virus via pore formation in host cell membrane" RELATED [] +synonym: "viral exit by cytolysis via pore formation in host cell membrane" EXACT [] +is_a: GO:0044659 ! viral release from host cell by cytolysis +relationship: has_part GO:0044658 ! pore formation in membrane of host by symbiont +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18852 xsd:anyURI +created_by: jl +creation_date: 2012-08-01T13:23:41Z + +[Term] +id: GO:0044662 +name: disruption by virus of host cell membrane +namespace: biological_process +def: "A process by which a virus has a negative effect on the functioning of a host cellular membrane." [GOC:jl] +synonym: "disruption by organism of host cell membrane" EXACT [] +synonym: "disruption by virus of host cell membrane" NARROW [GOC:bf, GOC:jl] +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0051673 ! membrane disruption in other organism +is_a: GO:0052025 ! modification by symbiont of host cell membrane +created_by: jl +creation_date: 2012-08-01T13:44:52Z + +[Term] +id: GO:0044663 +name: establishment or maintenance of cell type involved in phenotypic switching +namespace: biological_process +def: "A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns." [GOC:jl] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0036166 ! phenotypic switching +created_by: jl +creation_date: 2012-08-07T14:30:07Z + +[Term] +id: GO:0044664 +name: obsolete reversion of cell type to default state involved in phenotypic switching +namespace: biological_process +def: "OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns." [GOC:jl] +comment: This term was made obsolete because it is ambiguous. +is_obsolete: true +created_by: jl +creation_date: 2012-08-07T14:35:48Z + +[Term] +id: GO:0044665 +name: MLL1/2 complex +namespace: cellular_component +def: "A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species." [GOC:sart, PMID:21875999] +synonym: "Trx-containing complex" EXACT [] +is_a: GO:0035097 ! histone methyltransferase complex +created_by: jl +creation_date: 2012-08-07T14:44:12Z + +[Term] +id: GO:0044666 +name: MLL3/4 complex +namespace: cellular_component +def: "A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species." [GOC:sart, PMID:21875999] +synonym: "Trr/COMPASS-like complex" EXACT [] +is_a: GO:0035097 ! histone methyltransferase complex +created_by: jl +creation_date: 2012-08-07T14:46:40Z + +[Term] +id: GO:0044667 +name: (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out)." [GOC:crds] +synonym: "(R)-carnitine:gamma-butyrobetaine antiporter activity" EXACT [] +synonym: "L-carnitine:4-(trimethylammonio)butanoate antiporter activity" EXACT [] +synonym: "L-carnitine:gamma-butyrobetaine antiporter activity" EXACT [] +xref: RHEA:29427 +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:1901235 ! (R)-carnitine transmembrane transporter activity +is_a: GO:1901236 ! 4-(trimethylammonio)butanoate transmembrane transporter activity +created_by: jl +creation_date: 2012-08-08T11:17:12Z + +[Term] +id: GO:0044668 +name: sodium:malonate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in)." [GOC:crds] +xref: RHEA:33135 +is_a: GO:0017153 ! sodium:dicarboxylate symporter activity +is_a: GO:1901239 ! malonate(1-) transmembrane transporter activity +created_by: jl +creation_date: 2012-08-08T11:59:48Z + +[Term] +id: GO:0044669 +name: sodium:galactoside symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in)." [GOC:crds] +is_a: GO:0015370 ! solute:sodium symporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +created_by: jl +creation_date: 2012-08-08T12:55:32Z + +[Term] +id: GO:0044671 +name: sorocarp spore cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass)." [GOC:jl, GOC:rjd] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048837 ! sorocarp sorus development +created_by: jl +creation_date: 2012-08-08T13:10:48Z + +[Term] +id: GO:0044672 +name: acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex +namespace: cellular_component +def: "A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis." [GOC:mengo_curators, PMID:11607176, PMID:7693685, PMID:8955306] +synonym: "carbon monoxide dehydrogenase" BROAD [] +synonym: "carbon-monoxide:(acceptor) oxidoreductase complex" BROAD [] +synonym: "CO dehydrogenase complex" BROAD [] +synonym: "CO dehydrogenase/acetyl-CoA synthase complex" EXACT [] +synonym: "CODH" BROAD [] +synonym: "CODH/ACS complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2012-08-08T16:06:03Z + +[Term] +id: GO:0044673 +name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex +namespace: cellular_component +def: "A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420." [GOC:mengo_curators, PMID:14593448] +synonym: "FO-synthase complex" EXACT [] +is_a: GO:1990234 ! transferase complex +created_by: jl +creation_date: 2012-08-09T10:49:05Z + +[Term] +id: GO:0044674 +name: methyl coenzyme M reductase complex +namespace: cellular_component +def: "A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis." [GOC:mengo_curators, PMID:9367957] +is_a: GO:1990234 ! transferase complex +created_by: jl +creation_date: 2012-08-09T10:52:33Z + +[Term] +id: GO:0044675 +name: formyl-methanofuran dehydrogenase (tungsten enzyme) complex +namespace: cellular_component +def: "A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis." [GOC:mengo_curators, PMID:8125106, PMID:8575452] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2012-08-09T10:54:49Z + +[Term] +id: GO:0044676 +name: formyl-methanofuran dehydrogenase (molybdenum enzyme) complex +namespace: cellular_component +def: "A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis." [GOC:mengo_curators, PMID:1915887, PMID:8954165] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2012-08-09T10:56:51Z + +[Term] +id: GO:0044677 +name: methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex +namespace: cellular_component +def: "A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis." [GOC:mengo_curators, PMID:8477726] +synonym: "5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex" EXACT [] +synonym: "coenzyme M methyltransferase complex" BROAD [] +synonym: "methyl-H4MPT" BROAD [] +synonym: "N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2012-08-09T10:58:24Z + +[Term] +id: GO:0044678 +name: CoB-CoM heterodisulfide reductase complex +namespace: cellular_component +def: "A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine." [GOC:mengo_curators, PMID:8119281, PMID:8174566, PMID:9063468] +synonym: "coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex" EXACT [] +synonym: "hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex" EXACT [] +is_a: GO:1990204 ! oxidoreductase complex +created_by: jl +creation_date: 2012-08-09T11:01:43Z + +[Term] +id: GO:0044679 +name: methanophenazine reducing hydrogenase complex +namespace: cellular_component +def: "A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides." [GOC:mengo_curators, PMID:9555882] +is_a: GO:1990204 ! oxidoreductase complex +created_by: jl +creation_date: 2012-08-09T11:07:20Z + +[Term] +id: GO:0044680 +name: methylthiol:coenzyme M methyltransferase complex +namespace: cellular_component +def: "A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis." [GOC:mengo_curators, PMID:11073950, PMID:9371433] +synonym: "methylthiol coenzyme M methyl transferase complex" EXACT [] +synonym: "methylthiol:coenzyme M methyl transferase complex" EXACT [] +synonym: "methylthiol:CoM methyltransferase complex" EXACT [] +is_a: GO:0034708 ! methyltransferase complex +created_by: jl +creation_date: 2012-08-09T11:08:22Z + +[Term] +id: GO:0044681 +name: sulfopyruvate decarboxylase complex +namespace: cellular_component +def: "A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis." [GOC:mengo_curators, PMID:10940029] +is_a: GO:1902494 ! catalytic complex +created_by: jl +creation_date: 2012-08-09T11:12:47Z + +[Term] +id: GO:0044682 +name: archaeal-specific GTP cyclohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+." [GOC:mengo_curators, PMID:17497938] +synonym: "Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity" EXACT [] +synonym: "MptA activity" NARROW [] +is_a: GO:0003933 ! GTP cyclohydrolase activity +created_by: jl +creation_date: 2012-08-15T11:18:40Z + +[Term] +id: GO:0044683 +name: methylthiol:coenzyme M methyltransferase activity +namespace: molecular_function +def: "Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM." [MetaCyc:RXN-8125, PMID:9371433] +comment: This reaction is achieved by the catalysis of two successive steps carried out by the same enzyme - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, EC:2.1.1.90, methanol-corrinoid protein Co-methyltransferase, and EC:2.1.1.246, methylated methanol-specific corrinoid protein:coenzyme M methyltransferase). The cobalt is oxidized during methylation from the Co(I) state to the Co(III) state, and is reduced back to the Co(I) form during demethylation. +synonym: "methylthiol:coenzyme M methyl transferase activity" EXACT [] +xref: EC:2.1.1.251 +xref: MetaCyc:RXN-8125 +xref: RHEA:32667 +is_a: GO:0008168 ! methyltransferase activity +created_by: jl +creation_date: 2012-08-15T11:41:24Z + +[Term] +id: GO:0044684 +name: dihydromethanopterin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP." [GOC:mengo_curators, PMID:15028691] +xref: EC:1.5.99.15 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +relationship: part_of GO:2001118 ! tetrahydromethanopterin biosynthetic process +created_by: jl +creation_date: 2012-08-15T13:57:55Z + +[Term] +id: GO:0044685 +name: tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O." [GOC:mengo_curators, PMID:12902326] +xref: EC:2.1.2 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity +created_by: jl +creation_date: 2012-08-15T14:13:07Z + +[Term] +id: GO:0044686 +name: cysteate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-." [GOC:mengo_curators, PMID:19761441] +xref: EC:2.5.1.76 +xref: MetaCyc:RXN-11108 +xref: RHEA:26486 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: jl +creation_date: 2012-08-15T14:16:05Z + +[Term] +id: GO:0044687 +name: geranylfarnesyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate." [GOC:mengo_curators, PMID:20097171] +xref: EC:2.5.1.81 +xref: MetaCyc:RXN-8813 +xref: RHEA:25694 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: jl +creation_date: 2012-08-15T14:20:25Z + +[Term] +id: GO:0044688 +name: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+." [GOC:mengo_curators, PMID:19746965] +is_a: GO:0008081 ! phosphoric diester hydrolase activity +relationship: part_of GO:2001116 ! methanopterin-containing compound biosynthetic process +created_by: jl +creation_date: 2012-08-15T14:28:30Z + +[Term] +id: GO:0044689 +name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+." [GOC:mengo_curators, PMID:11948155, PMID:14593448] +synonym: "FO synthase" EXACT [] +xref: EC:2.5.1.147 +xref: MetaCyc:RXN-8079 +xref: RHEA:27373 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: jl +creation_date: 2012-08-15T14:33:17Z + +[Term] +id: GO:0044691 +name: tooth eruption +namespace: biological_process +def: "The tooth development process in which the teeth enter the mouth and become visible." [Wikipedia:Tooth_eruption] +xref: Wikipedia:Tooth_eruption +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0042476 ! odontogenesis +created_by: jl +creation_date: 2012-08-15T14:58:17Z + +[Term] +id: GO:0044692 +name: exoribonuclease activator activity +namespace: molecular_function +def: "Binds to and increases the activity of an exoribonuclease." [GOC:rb, PMID:22570495] +is_a: GO:0008047 ! enzyme activator activity +relationship: part_of GO:0032075 ! positive regulation of nuclease activity +created_by: jl +creation_date: 2012-08-15T15:13:57Z + +[Term] +id: GO:0044693 +name: trehalose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in)." [PMID:11136464] +synonym: "trehalose:hydrogen symporter activity" EXACT [] +is_a: GO:0005351 ! carbohydrate:proton symporter activity +is_a: GO:0015574 ! trehalose transmembrane transporter activity +created_by: jl +creation_date: 2012-08-15T15:19:27Z + +[Term] +id: GO:0044694 +name: pore-mediated entry of viral genome into host cell +namespace: biological_process +def: "Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail." [GOC:jl, UniProtKB-KW:KW-1172, VZ:979] +comment: This mechanism is used by animal viruses such as poliovirus. Various tailed bacteriophages also carry specialized proteins which open a pore or a channel in the host membrane(s) to allow genome delivery into host cytoplasm. +synonym: "membrane puncture-mediated penetration of viral genome into host cell" RELATED [UniProtKB-KW:KW-1172] +synonym: "pore-mediated penetration of viral genome into host cell" EXACT [] +synonym: "viral entry via genome injection" EXACT [] +synonym: "viral genome delivery via icosahedral vertex" NARROW [] +synonym: "viral genome translocation" EXACT [] +synonym: "viral pore-forming protein" RELATED [GOC:bf] +xref: VZ:979 "Pore-mediated penetration of viral genome into host cell" +is_a: GO:0046718 ! viral entry into host cell +is_a: GO:0046794 ! transport of virus +relationship: has_part GO:0039707 ! pore formation by virus in membrane of host cell +created_by: jl +creation_date: 2012-08-16T11:08:02Z + +[Term] +id: GO:0044695 +name: Dsc E3 ubiquitin ligase complex +namespace: cellular_component +def: "An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism." [GOC:mah, GOC:vw, PMID:21504829] +is_a: GO:0000151 ! ubiquitin ligase complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0031090 ! organelle membrane +created_by: jl +creation_date: 2012-08-16T13:41:48Z + +[Term] +id: GO:0044696 +name: killing by virus of host cell by post-segregational killing +namespace: biological_process +def: "The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes." [GOC:bf, GOC:jl, PMID:11222604, Wikipedia:Toxin-antitoxin_system] +comment: Note that this process occurs after the cell division partitioning event. +synonym: "killing by virus of host cell by PSK" EXACT [] +synonym: "killing by virus of host cell by toxin-antitoxin system" EXACT [] +is_a: GO:0039633 ! killing by virus of host cell +created_by: jl +creation_date: 2012-08-16T13:58:18Z + +[Term] +id: GO:0044697 +name: HICS complex +namespace: cellular_component +def: "A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins." [PMID:22623719] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2012-09-19T13:30:22Z + +[Term] +id: GO:0044698 +name: morphogenesis of symbiont in host cell +namespace: biological_process +def: "The process in which a symbiont undergoes a change in shape or form, within the host's cell." [GOC:jl] +is_a: GO:0009653 ! anatomical structure morphogenesis +is_a: GO:0044111 ! development involved in symbiotic interaction +relationship: part_of GO:0044118 ! development of symbiont in host cell +created_by: jl +creation_date: 2012-09-19T14:10:53Z + +[Term] +id: GO:0044701 +name: obsolete response to stimulus by single organism +namespace: biological_process +def: "OBSOLETE. A response to a stimulus that involves only one organism." [GOC:jl] +comment: This term was made obsolete because we decided that all responses are single-organism. +synonym: "response to stimulus by single organism" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2012-09-19T15:40:57Z + +[Term] +id: GO:0044703 +name: multi-organism reproductive process +namespace: biological_process +def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051704 ! multi-organism process +created_by: jl +creation_date: 2012-09-19T15:56:30Z + +[Term] +id: GO:0044705 +name: multi-organism reproductive behavior +namespace: biological_process +def: "The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species." [GOC:jl, GOC:pr] +is_a: GO:0019098 ! reproductive behavior +created_by: jl +creation_date: 2012-09-19T16:02:12Z + +[Term] +id: GO:0044706 +name: multi-multicellular organism process +namespace: biological_process +def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0051704 ! multi-organism process +created_by: jl +creation_date: 2012-09-19T16:06:16Z + +[Term] +id: GO:0044713 +name: 2-hydroxy-adenosine triphosphate pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-adenosine-triphosphate + H2O = 2-hydroxy-adenosine phosphate + diphosphate." [GOC:pde, PMID:11139615] +synonym: "2-hydroxy-ATP pyrophosphatase activity" EXACT [] +xref: Reactome:R-HSA-2395872 "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP" +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: jl +creation_date: 2012-10-18T13:22:38Z + +[Term] +id: GO:0044714 +name: 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-(deoxy)adenosine-triphosphate + H2O = 2-hydroxy-(deoxy)adenosine phosphate + diphosphate." [GOC:pde, PMID:11139615] +synonym: "2-hydroxy-(d)ATP pyrophosphatase activity" EXACT [] +xref: Reactome:R-HSA-2395818 "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP" +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity +created_by: jl +creation_date: 2012-10-18T13:24:32Z + +[Term] +id: GO:0044715 +name: 8-oxo-dGDP phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate." [GOC:pde, PMID:22556419] +xref: Reactome:R-HSA-2395873 "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP" +xref: Reactome:R-HSA-2395879 "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP" +is_a: GO:0017110 ! nucleoside-diphosphatase activity +created_by: jl +creation_date: 2012-10-18T13:31:09Z + +[Term] +id: GO:0044716 +name: 8-oxo-GDP phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate." [GOC:pde, PMID:22556419] +is_a: GO:0017110 ! nucleoside-diphosphatase activity +created_by: jl +creation_date: 2012-10-18T13:32:39Z + +[Term] +id: GO:0044717 +name: 8-hydroxy-dADP phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate." [GOC:pde, PMID:22556419] +xref: Reactome:R-HSA-2395965 "NUDT18 hydrolyses 8-OH-dADP to 8-OH-dAMP" +is_a: GO:0017110 ! nucleoside-diphosphatase activity +created_by: jl +creation_date: 2012-10-18T13:33:32Z + +[Term] +id: GO:0044718 +name: siderophore transmembrane transport +namespace: biological_process +def: "The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore." [GOC:jl] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "siderophore membrane transport" EXACT [] +is_a: GO:0015891 ! siderophore transport +is_a: GO:0034755 ! iron ion transmembrane transport +created_by: jl +creation_date: 2012-10-18T13:43:56Z + +[Term] +id: GO:0044719 +name: regulation of imaginal disc-derived wing size +namespace: biological_process +def: "Any process that modulates the size of an imaginal disc-derived wing." [PMID:21393605] +is_a: GO:0090066 ! regulation of anatomical structure size +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +created_by: jl +creation_date: 2012-10-18T13:49:12Z + +[Term] +id: GO:0044720 +name: negative regulation of imaginal disc-derived wing size +namespace: biological_process +def: "Any process that reduces the size of an imaginal disc-derived wing." [PMID:21393605] +is_a: GO:0044719 ! regulation of imaginal disc-derived wing size +created_by: jl +creation_date: 2012-10-18T13:50:49Z + +[Term] +id: GO:0044721 +name: protein import into peroxisome matrix, substrate release +namespace: biological_process +def: "The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane." [PMID:21976670] +is_a: GO:0043624 ! cellular protein complex disassembly +relationship: part_of GO:0016558 ! protein import into peroxisome matrix +created_by: jl +creation_date: 2012-10-18T14:07:40Z + +[Term] +id: GO:0044722 +name: renal phosphate excretion +namespace: biological_process +def: "The elimination by an organism of phosphate ions in the urine." [GOC:jl, PMID:21451460] +synonym: "renal phosphate ion excretion" EXACT [] +is_a: GO:0003014 ! renal system process +is_a: GO:0007588 ! excretion +created_by: jl +creation_date: 2012-10-18T14:54:00Z + +[Term] +id: GO:0044725 +name: chromatin reprogramming in the zygote +namespace: biological_process +def: "The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process." [GOC:sp, PMID:22868271] +is_a: GO:0043045 ! DNA methylation involved in embryo development +created_by: jl +creation_date: 2012-10-24T13:53:28Z + +[Term] +id: GO:0044726 +name: protection of DNA demethylation of female pronucleus +namespace: biological_process +def: "The protection of the maternal genome from DNA demethylation in the zygote following fertilization." [GOC:sp, PMID:22868271] +is_a: GO:0044030 ! regulation of DNA methylation +relationship: part_of GO:0044725 ! chromatin reprogramming in the zygote +created_by: jl +creation_date: 2012-10-24T14:10:36Z + +[Term] +id: GO:0044727 +name: DNA demethylation of male pronucleus +namespace: biological_process +def: "The active DNA demethylation of the paternal genome that takes place before the first cell division." [GOC:sp, PMID:22868271] +is_a: GO:0043045 ! DNA methylation involved in embryo development +relationship: part_of GO:0044725 ! chromatin reprogramming in the zygote +created_by: jl +creation_date: 2012-10-24T14:25:35Z + +[Term] +id: GO:0044728 +name: DNA methylation or demethylation +namespace: biological_process +def: "The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule." [GOC:jl] +synonym: "changes in DNA methylation" RELATED [] +is_a: GO:0006304 ! DNA modification +created_by: jl +creation_date: 2012-10-24T14:49:41Z + +[Term] +id: GO:0044729 +name: hemi-methylated DNA-binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks." [GOC:imk, GOC:sp, PMID:18772889] +synonym: "double-stranded hemi-methylated DNA binding" EXACT [] +is_a: GO:0003690 ! double-stranded DNA binding +created_by: jl +creation_date: 2012-10-24T14:58:14Z + +[Term] +id: GO:0044730 +name: bone sialoprotein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin." [PMID:10642520] +synonym: "bone sialoprotein II binding" EXACT [] +xref: InterPro:IPR008412 +is_a: GO:0005515 ! protein binding +is_a: GO:0050840 ! extracellular matrix binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: jl +creation_date: 2012-11-06T13:05:56Z + +[Term] +id: GO:0044731 +name: Ost-alpha/Ost-beta complex +namespace: cellular_component +def: "A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity." [PMID:17650074, PMID:22535958] +synonym: "(Ost)2 complex" RELATED [] +synonym: "Ost alpha-Ost beta complex" EXACT [] +synonym: "SLC51 complex" EXACT [] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: jl +creation_date: 2012-11-06T13:42:06Z + +[Term] +id: GO:0044732 +name: mitotic spindle pole body +namespace: cellular_component +def: "The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome." [GOC:mah, GOC:vw] +is_a: GO:0005816 ! spindle pole body +created_by: jl +creation_date: 2012-11-06T15:44:02Z + +[Term] +id: GO:0044733 +name: envenomation resulting in modulation of acid-sensing ion channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism." [GOC:fj, GOC:jl, PMID:23034652] +synonym: "envenomation resulting in modulation of ASIC channel activity in other organism" EXACT [] +is_a: GO:0044560 ! envenomation resulting in modulation of ion channel activity in other organism +relationship: has_part GO:0044737 ! modulation of acid-sensing ion channel in other organism +created_by: jl +creation_date: 2012-11-06T15:58:36Z + +[Term] +id: GO:0044734 +name: envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism." [GOC:fj, GOC:jl, PMID:23034652] +synonym: "envenomation resulting in positive regulation of ASIC channel activity in other organism" EXACT [] +is_a: GO:0044733 ! envenomation resulting in modulation of acid-sensing ion channel activity in other organism +relationship: has_part GO:0044739 ! positive regulation of acid-sensing ion channel in other organism +created_by: jl +creation_date: 2012-11-06T16:02:01Z + +[Term] +id: GO:0044735 +name: envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism." [GOC:fj, GOC:jl, PMID:23034652] +synonym: "envenomation resulting in negative regulation of ASIC channel activity in other organism" EXACT [] +is_a: GO:0044733 ! envenomation resulting in modulation of acid-sensing ion channel activity in other organism +relationship: has_part GO:0044738 ! negative regulation of acid-sensing ion channel in other organism +created_by: jl +creation_date: 2012-11-06T16:05:58Z + +[Term] +id: GO:0044736 +name: acid-sensing ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex." [GOC:jl] +synonym: "ASIC activity" EXACT [] +xref: Reactome:R-HSA-2671885 "ASICs transport extracellular Na+ to cytosol" +xref: Wikipedia:Acid-sensing_ion_channel +is_a: GO:0015280 ! ligand-gated sodium channel activity +created_by: jl +creation_date: 2012-11-06T16:36:37Z + +[Term] +id: GO:0044737 +name: modulation of acid-sensing ion channel in other organism +namespace: biological_process +def: "Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism." [GOC:jl] +synonym: "regulation of acid-sensing ion channel in other organism" EXACT [] +synonym: "regulation of ASIC channel in other organism" EXACT [] +is_a: GO:0044561 ! modulation of ion channel activity in other organism +created_by: jl +creation_date: 2012-11-06T16:51:24Z + +[Term] +id: GO:0044738 +name: negative regulation of acid-sensing ion channel in other organism +namespace: biological_process +def: "Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism." [GOC:jl] +synonym: "negative regulation of ASIC channel in other organism" EXACT [] +is_a: GO:0044737 ! modulation of acid-sensing ion channel in other organism +created_by: jl +creation_date: 2012-11-06T16:55:23Z + +[Term] +id: GO:0044739 +name: positive regulation of acid-sensing ion channel in other organism +namespace: biological_process +def: "Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism." [GOC:jl] +synonym: "positive regulation of ASIC channel in other organism" EXACT [] +is_a: GO:0044737 ! modulation of acid-sensing ion channel in other organism +created_by: jl +creation_date: 2012-11-06T16:56:27Z + +[Term] +id: GO:0044740 +name: negative regulation of sensory perception of pain in other organism +namespace: biological_process +def: "A process that negatively regulates the sensory perception of pain in a different organism." [GOC:fj, GOC:jl] +synonym: "inhibition of sensory perception of pain in another organism" EXACT [] +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0044465 ! modulation of sensory perception of pain in other organism +created_by: jl +creation_date: 2012-11-07T13:43:10Z + +[Term] +id: GO:0044741 +name: envenomation resulting in negative regulation of sensory perception of pain in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism." [GOC:fj, GOC:jl, PMID:23034652] +synonym: "envenomation resulting in inhibition of sensory perception of pain in other organism" EXACT [] +is_a: GO:0044742 ! envenomation resulting in modulation of sensory perception of pain in other organism +relationship: has_part GO:0044740 ! negative regulation of sensory perception of pain in other organism +created_by: jl +creation_date: 2012-11-07T14:02:14Z + +[Term] +id: GO:0044742 +name: envenomation resulting in modulation of sensory perception of pain in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism." [GOC:fj, GOC:jl, PMID:23034652] +synonym: "envenomation resulting in regulation of sensory perception of pain in other organism" EXACT [] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:0044465 ! modulation of sensory perception of pain in other organism +created_by: jl +creation_date: 2012-11-07T14:26:38Z + +[Term] +id: GO:0044743 +name: protein transmembrane import into intracellular organelle +namespace: biological_process +def: "The directed movement of proteins into an intracellular organelle, across a membrane." [GOC:jl] +is_a: GO:0017038 ! protein import +is_a: GO:0071806 ! protein transmembrane transport +is_a: GO:0072594 ! establishment of protein localization to organelle +created_by: jl +creation_date: 2012-11-07T15:37:36Z + +[Term] +id: GO:0044747 +name: mature miRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends." [PMID:22055292, PMID:22055293] +synonym: "miRNA 3' end terminal trimming" BROAD [] +synonym: "miRNA 3'-end processing" BROAD [] +synonym: "miRNA trimming" BROAD [] +is_a: GO:0010586 ! miRNA metabolic process +is_a: GO:0043628 ! ncRNA 3'-end processing +relationship: part_of GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +created_by: jl +creation_date: 2012-11-15T13:45:21Z + +[Term] +id: GO:0044748 +name: 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA." [GOC:sart] +synonym: "exonucleolytic trimming to generate 3' end of miRNA" BROAD [] +is_a: GO:0000175 ! 3'-5'-exoribonuclease activity +intersection_of: GO:0000175 ! 3'-5'-exoribonuclease activity +intersection_of: part_of GO:0044747 ! mature miRNA 3'-end processing +relationship: part_of GO:0044747 ! mature miRNA 3'-end processing +created_by: jl +creation_date: 2012-11-20T13:48:29Z + +[Term] +id: GO:0044750 +name: high-affinity nickel cation transmembrane transporter activity +namespace: molecular_function +def: "Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:jl] +is_a: GO:0015099 ! nickel cation transmembrane transporter activity +created_by: jl +creation_date: 2012-11-20T15:15:59Z + +[Term] +id: GO:0044751 +name: cellular response to human chorionic gonadotropin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus." [PMID:21325635] +synonym: "cellular response to human chorionic gonadotrophin stimulus" EXACT [GOC:dph] +is_a: GO:0044752 ! response to human chorionic gonadotropin +is_a: GO:0071371 ! cellular response to gonadotropin stimulus +created_by: jl +creation_date: 2012-11-20T16:19:45Z + +[Term] +id: GO:0044752 +name: response to human chorionic gonadotropin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus." [PMID:21325635] +synonym: "response to human chorionic gonadotropin stimulus" EXACT [GOC:dos] +is_a: GO:0034698 ! response to gonadotropin +created_by: jl +creation_date: 2012-11-20T16:21:08Z + +[Term] +id: GO:0044753 +name: amphisome +namespace: cellular_component +def: "Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes." [GOC:autophagy, GOC:sart, PMID:19008921, PMID:9705327] +is_a: GO:0005776 ! autophagosome +created_by: jl +creation_date: 2012-11-27T15:35:25Z + +[Term] +id: GO:0044754 +name: autolysosome +namespace: cellular_component +def: "A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases." [GOC:sart, NIF_Subcellular:sao8444068431, PMID:19008921] +synonym: "autophagolysosome" EXACT [] +synonym: "AVd" EXACT [] +synonym: "degrading autophagic vacuole" EXACT [] +xref: NIF_Subcellular:sao8444068431 +is_a: GO:0005767 ! secondary lysosome +is_a: GO:0005776 ! autophagosome +created_by: jl +creation_date: 2012-11-27T15:42:12Z + +[Term] +id: GO:0044758 +name: modulation by symbiont of host synaptic transmission +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism." [GOC:jl] +synonym: "regulation by symbiont of host synaptic transmission" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0007268 ! chemical synaptic transmission +created_by: jl +creation_date: 2012-12-06T15:34:05Z + +[Term] +id: GO:0044759 +name: negative regulation by symbiont of host synaptic transmission +namespace: biological_process +def: "Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism." [GOC:jl] +is_a: GO:0044758 ! modulation by symbiont of host synaptic transmission +is_a: GO:0050805 ! negative regulation of synaptic transmission +created_by: jl +creation_date: 2012-12-06T15:37:25Z + +[Term] +id: GO:0044760 +name: modulation by symbiont of host cholinergic synaptic transmission +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism." [GOC:jl] +synonym: "regulation by symbiont of host cholinergic synaptic transmission" EXACT [] +is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic +is_a: GO:0044758 ! modulation by symbiont of host synaptic transmission +created_by: jl +creation_date: 2012-12-06T15:39:46Z + +[Term] +id: GO:0044761 +name: negative regulation by symbiont of host cholinergic synaptic transmission +namespace: biological_process +def: "Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism." [GOC:jl] +is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic +is_a: GO:0044759 ! negative regulation by symbiont of host synaptic transmission +is_a: GO:0044760 ! modulation by symbiont of host cholinergic synaptic transmission +created_by: jl +creation_date: 2012-12-06T15:43:53Z + +[Term] +id: GO:0044762 +name: negative regulation by symbiont of host neurotransmitter secretion +namespace: biological_process +def: "Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism." [GOC:jl] +is_a: GO:0044079 ! modulation by symbiont of host neurotransmitter secretion +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: negatively_regulates GO:0007269 ! neurotransmitter secretion +created_by: jl +creation_date: 2012-12-06T15:52:20Z + +[Term] +id: GO:0044764 +name: multi-organism cellular process +namespace: biological_process +def: "Any process that is carried out at the cellular level which involves another organism of the same or different species." [GOC:jl] +is_a: GO:0009987 ! cellular process +is_a: GO:0051704 ! multi-organism process +created_by: jl +creation_date: 2012-12-11T17:00:50Z + +[Term] +id: GO:0044766 +name: multi-organism transport +namespace: biological_process +def: "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism." [GOC:jl] +is_a: GO:0006810 ! transport +is_a: GO:1902579 ! multi-organism localization +created_by: jl +creation_date: 2012-12-13T16:25:50Z + +[Term] +id: GO:0044768 +name: NMS complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly." [GOC:vw, PMID:22561345] +synonym: "KMN complex interaction involved in chromosome segregation" EXACT [] +synonym: "KMN kinetochore network assembly" EXACT [] +synonym: "KMN kinetochore network formation" EXACT [] +synonym: "KMN network assembly involved in chromosome segregation" EXACT [] +synonym: "KNL-1-Mis12-Ndc80 assembly" EXACT [] +synonym: "KNL-1-Mis12-Ndc80 formation" EXACT [] +synonym: "Ndc80-MIND-Spc7 complex assembly" EXACT [] +synonym: "Ndc80-MIND-Spc7 complex formation" EXACT [] +synonym: "NMS complex assembly involved in kinetochore assembly" EXACT [] +synonym: "NMS complex association involved in chromosome segregation" EXACT [] +synonym: "NMS complex formation" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0051382 ! kinetochore assembly +created_by: jl +creation_date: 2012-12-19T14:44:56Z + +[Term] +id: GO:0044769 +name: ATPase activity, coupled to transmembrane movement of ions, rotational mechanism +namespace: molecular_function +def: "Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism." [GOC:jl] +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +created_by: jl +creation_date: 2013-02-20T13:41:38Z + +[Term] +id: GO:0044770 +name: cell cycle phase transition +namespace: biological_process +def: "The cell cycle process by which a cell commits to entering the next cell cycle phase." [GOC:mtg_cell_cycle] +synonym: "cell cycle transition" EXACT [] +is_a: GO:0022402 ! cell cycle process +created_by: jl +creation_date: 2013-02-28T12:54:59Z + +[Term] +id: GO:0044771 +name: meiotic cell cycle phase transition +namespace: biological_process +def: "The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase." [GOC:mtg_cell_cycle] +synonym: "cell cycle transition" BROAD [] +is_a: GO:0044770 ! cell cycle phase transition +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0044770 ! cell cycle phase transition +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2013-02-28T13:08:17Z + +[Term] +id: GO:0044772 +name: mitotic cell cycle phase transition +namespace: biological_process +def: "The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase." [GOC:mtg_cell_cycle] +is_a: GO:0044770 ! cell cycle phase transition +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0044770 ! cell cycle phase transition +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-02-28T13:09:33Z + +[Term] +id: GO:0044773 +name: mitotic DNA damage checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] +is_a: GO:0000077 ! DNA damage checkpoint +is_a: GO:0044774 ! mitotic DNA integrity checkpoint +intersection_of: GO:0000077 ! DNA damage checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-02-28T15:55:25Z + +[Term] +id: GO:0044774 +name: mitotic DNA integrity checkpoint +namespace: biological_process +alt_id: GO:0070683 +def: "A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G2/M transition decatenation checkpoint" EXACT [] +synonym: "topo II checkpoint" EXACT [GOC:jp] +synonym: "topoisomerase II checkpoint" EXACT [GOC:jp] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:0031570 ! DNA integrity checkpoint +intersection_of: GO:0031570 ! DNA integrity checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-02-28T16:07:26Z + +[Term] +id: GO:0044775 +name: DNA polymerase III, beta sliding clamp processivity factor complex +namespace: cellular_component +def: "A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species." [GOC:jl, UniProt:O73947] +is_a: GO:0044796 ! DNA polymerase processivity factor complex +relationship: part_of GO:0009360 ! DNA polymerase III complex +created_by: jl +creation_date: 2013-03-13T13:59:48Z + +[Term] +id: GO:0044776 +name: DNA polymerase III, core complex +namespace: cellular_component +def: "The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities." [GOC:jl, UniProt:P06710] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0009360 ! DNA polymerase III complex +created_by: jl +creation_date: 2013-03-13T14:09:38Z + +[Term] +id: GO:0044777 +name: single-stranded DNA-binding protein complex +namespace: cellular_component +def: "A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair." [GOC:jl, UniProt:P0AGE0] +synonym: "SSB complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0009295 ! nucleoid +created_by: jl +creation_date: 2013-03-14T13:14:00Z + +[Term] +id: GO:0044778 +name: meiotic DNA integrity checkpoint +namespace: biological_process +def: "A meiotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." [GOC:mtg_cell_cycle] +is_a: GO:0031570 ! DNA integrity checkpoint +is_a: GO:0033313 ! meiotic cell cycle checkpoint +intersection_of: GO:0031570 ! DNA integrity checkpoint +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2013-03-20T16:46:06Z + +[Term] +id: GO:0044779 +name: meiotic spindle checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle." [GOC:mtg_cell_cycle] +is_a: GO:0031577 ! spindle checkpoint +is_a: GO:0033313 ! meiotic cell cycle checkpoint +is_a: GO:1902103 ! negative regulation of metaphase/anaphase transition of meiotic cell cycle +intersection_of: GO:0031577 ! spindle checkpoint +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2013-03-21T14:01:28Z + +[Term] +id: GO:0044780 +name: bacterial-type flagellum assembly +namespace: biological_process +def: "The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility." [GOC:jl] +synonym: "bacterial flagellum assembly" EXACT [] +is_a: GO:0030031 ! cell projection assembly +is_a: GO:0044781 ! bacterial-type flagellum organization +is_a: GO:0070925 ! organelle assembly +created_by: jl +creation_date: 2013-03-27T15:00:43Z + +[Term] +id: GO:0044781 +name: bacterial-type flagellum organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility." [GOC:jl] +is_a: GO:0006996 ! organelle organization +is_a: GO:0030030 ! cell projection organization +created_by: jl +creation_date: 2013-03-27T15:07:00Z + +[Term] +id: GO:0044782 +name: cilium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +subset: goslim_drosophila +synonym: "microtubule-based flagellum organization" EXACT [] +is_a: GO:0006996 ! organelle organization +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +created_by: jl +creation_date: 2013-03-27T15:09:58Z + +[Term] +id: GO:0044783 +name: G1 DNA damage checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] +synonym: "G1/S DNA damage checkpoint" EXACT [] +is_a: GO:0000077 ! DNA damage checkpoint +created_by: jl +creation_date: 2013-05-02T12:52:39Z + +[Term] +id: GO:0044784 +name: metaphase/anaphase transition of cell cycle +namespace: biological_process +def: "The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0033045 ! regulation of sister chromatid segregation +is_a: GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2013-05-02T13:09:34Z + +[Term] +id: GO:0044785 +name: metaphase/anaphase transition of meiotic cell cycle +namespace: biological_process +def: "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis." [GOC:mtg_cell_cycle] +synonym: "meiotic metaphase/anaphase transition" EXACT [] +is_a: GO:0044771 ! meiotic cell cycle phase transition +is_a: GO:0044784 ! metaphase/anaphase transition of cell cycle +intersection_of: GO:0044784 ! metaphase/anaphase transition of cell cycle +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2013-05-02T13:11:28Z + +[Term] +id: GO:0044786 +name: cell cycle DNA replication +namespace: biological_process +def: "The DNA-dependent DNA replication that takes place as part of the cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0006261 ! DNA-dependent DNA replication +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006261 ! DNA-dependent DNA replication +intersection_of: part_of GO:0007049 ! cell cycle +created_by: jl +creation_date: 2013-05-02T15:52:22Z + +[Term] +id: GO:0044787 +name: bacterial-type DNA replication +namespace: biological_process +def: "The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome." [GOC:mtg_cell_cycle] +synonym: "bacterial-type cell cycle DNA replication" EXACT [] +is_a: GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-05-02T15:54:16Z + +[Term] +id: GO:0044788 +name: modulation by host of viral process +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected." [GOC:jl] +is_a: GO:0051851 ! modulation by host of symbiont process +created_by: jl +creation_date: 2013-06-06T10:50:49Z + +[Term] +id: GO:0044789 +name: modulation by host of viral release from host cell +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells." [GOC:jl, PMID:18305167] +is_a: GO:0044788 ! modulation by host of viral process +is_a: GO:1902186 ! regulation of viral release from host cell +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: regulates GO:0019076 ! viral release from host cell +created_by: jl +creation_date: 2013-06-06T10:51:10Z + +[Term] +id: GO:0044790 +name: negative regulation by host of viral release from host cell +namespace: biological_process +def: "A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells." [GOC:jl, PMID:18305167] +is_a: GO:0044789 ! modulation by host of viral release from host cell +is_a: GO:0044793 ! negative regulation by host of viral process +is_a: GO:1902187 ! negative regulation of viral release from host cell +intersection_of: GO:0044793 ! negative regulation by host of viral process +intersection_of: negatively_regulates GO:0019076 ! viral release from host cell +created_by: jl +creation_date: 2013-06-06T10:51:27Z + +[Term] +id: GO:0044791 +name: positive regulation by host of viral release from host cell +namespace: biological_process +def: "A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells." [GOC:jl] +is_a: GO:0044789 ! modulation by host of viral release from host cell +is_a: GO:0044794 ! positive regulation by host of viral process +is_a: GO:1902188 ! positive regulation of viral release from host cell +intersection_of: GO:0044794 ! positive regulation by host of viral process +intersection_of: positively_regulates GO:0019076 ! viral release from host cell +created_by: jl +creation_date: 2013-06-06T10:51:48Z + +[Term] +id: GO:0044793 +name: negative regulation by host of viral process +namespace: biological_process +def: "A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected." [GOC:jl] +is_a: GO:0044788 ! modulation by host of viral process +is_a: GO:0048525 ! negative regulation of viral process +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: negatively_regulates GO:0016032 ! viral process +created_by: jl +creation_date: 2013-06-06T11:16:00Z + +[Term] +id: GO:0044794 +name: positive regulation by host of viral process +namespace: biological_process +def: "A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected." [GOC:jl] +is_a: GO:0044788 ! modulation by host of viral process +is_a: GO:0048524 ! positive regulation of viral process +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: positively_regulates GO:0016032 ! viral process +created_by: jl +creation_date: 2013-06-06T11:33:51Z + +[Term] +id: GO:0044795 +name: trans-Golgi network to recycling endosome transport +namespace: biological_process +def: "The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes." [GOC:lb, PMID:18779367] +is_a: GO:0016197 ! endosomal transport +created_by: jl +creation_date: 2013-08-27T16:04:00Z + +[Term] +id: GO:0044796 +name: DNA polymerase processivity factor complex +namespace: cellular_component +def: "A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication." [GOC:bhm, GOC:jl] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: jl +creation_date: 2013-08-28T11:16:14Z + +[Term] +id: GO:0044799 +name: NarGHI complex +namespace: cellular_component +def: "A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit." [GOC:bhm, PMID:11289299, PMID:12910261, PMID:17964535] +synonym: "cytoplasmic membrane-bound quinol-nitrate oxidoreductase" EXACT [] +synonym: "nitrate reductase A" EXACT [] +is_a: GO:0009325 ! nitrate reductase complex +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0070470 ! plasma membrane respirasome +created_by: jl +creation_date: 2013-08-29T14:17:41Z + +[Term] +id: GO:0044800 +name: multi-organism membrane fusion +namespace: biological_process +def: "The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism." [GOC:jl] +is_a: GO:0044803 ! multi-organism membrane organization +is_a: GO:0061025 ! membrane fusion +created_by: jl +creation_date: 2013-09-10T15:06:11Z + +[Term] +id: GO:0044803 +name: multi-organism membrane organization +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism." [GOC:jl] +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0061024 ! membrane organization +created_by: jl +creation_date: 2013-09-10T15:11:41Z + +[Term] +id: GO:0044804 +name: autophagy of nucleus +namespace: biological_process +def: "A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded." [GOC:autophagy, GOC:jl, PMID:24013549] +synonym: "nucleophagy" RELATED [] +synonym: "nucleus degradation" EXACT [] +is_a: GO:0006914 ! autophagy +created_by: jl +creation_date: 2013-09-10T15:50:25Z + +[Term] +id: GO:0044805 +name: late nucleophagy +namespace: biological_process +def: "A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM." [GOC:dgf, GOC:jl, PMID:22768199] +synonym: "LN" EXACT [] +is_a: GO:0044804 ! autophagy of nucleus +created_by: jl +creation_date: 2013-09-10T15:58:23Z + +[Term] +id: GO:0044806 +name: G-quadruplex DNA unwinding +namespace: biological_process +def: "The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'." [GOC:jl, GOC:se, PMID:23657261] +is_a: GO:0032392 ! DNA geometric change +created_by: jl +creation_date: 2013-09-10T16:16:16Z + +[Term] +id: GO:0044807 +name: macrophage migration inhibitory factor production +namespace: biological_process +def: "The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "MIF production" EXACT [] +is_a: GO:0001816 ! cytokine production +created_by: jl +creation_date: 2013-09-11T12:04:09Z + +[Term] +id: GO:0044808 +name: Oncostatin M production +namespace: biological_process +def: "The appearance of Oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "OSM production" EXACT [] +is_a: GO:0001816 ! cytokine production +created_by: jl +creation_date: 2013-09-11T12:18:00Z + +[Term] +id: GO:0044809 +name: chemokine (C-C motif) ligand 17 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CCL17 production" EXACT [] +synonym: "TARC production" EXACT [] +synonym: "thymus and activation regulated chemokine production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: jl +creation_date: 2013-09-11T12:21:31Z + +[Term] +id: GO:0044812 +name: fermentative hydrogen production +namespace: biological_process +def: "The fermentation of organic substances with a net release of hydrogen." [GOC:mengo_curators] +synonym: "carbohydrate fermentation" EXACT [] +xref: Wikipedia:Fermentative_hydrogen_production +is_a: GO:0006113 ! fermentation +is_a: GO:1902422 ! hydrogen biosynthetic process +created_by: jl +creation_date: 2013-09-18T14:09:47Z + +[Term] +id: GO:0044813 +name: glycolytic fermentation via PFOR pathway +namespace: biological_process +def: "The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species." [GOC:mengo_curators, PMID:20395274, PMID:20692761] +is_a: GO:0019660 ! glycolytic fermentation +intersection_of: GO:0019660 ! glycolytic fermentation +intersection_of: has_part GO:0019164 ! pyruvate synthase activity +relationship: has_part GO:0019164 ! pyruvate synthase activity +created_by: jl +creation_date: 2013-09-18T16:04:00Z + +[Term] +id: GO:0044814 +name: glycolytic fermentation via PFL pathway +namespace: biological_process +def: "The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli." [GOC:mengo_curators, PMID:20395274, PMID:20692761] +is_a: GO:0019660 ! glycolytic fermentation +intersection_of: GO:0019660 ! glycolytic fermentation +intersection_of: has_part GO:0008861 ! formate C-acetyltransferase activity +relationship: has_part GO:0008861 ! formate C-acetyltransferase activity +created_by: jl +creation_date: 2013-09-18T16:56:02Z + +[Term] +id: GO:0044815 +name: DNA packaging complex +namespace: cellular_component +def: "A protein complex that plays a role in the process of DNA packaging." [GOC:jl] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2013-09-19T11:33:45Z + +[Term] +id: GO:0044816 +name: Nsk1-Dlc1 complex +namespace: cellular_component +def: "A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation." [GOC:vw, PMID:22065639] +is_a: GO:0032991 ! protein-containing complex +created_by: jl +creation_date: 2013-10-21T14:38:16Z + +[Term] +id: GO:0044817 +name: hydrogen generation via biophotolysis +namespace: biological_process +def: "The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae." [GOC:mengo_curators, PMID:20395274, PMID:20692761] +synonym: "hydrogen biosynthesis via biophotolysis" EXACT [] +is_a: GO:1902422 ! hydrogen biosynthetic process +created_by: jl +creation_date: 2013-10-22T14:36:54Z + +[Term] +id: GO:0044818 +name: mitotic G2/M transition checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:0010972 ! negative regulation of G2/M transition of mitotic cell cycle +created_by: jl +creation_date: 2013-11-19T14:20:00Z + +[Term] +id: GO:0044819 +name: mitotic G1/S transition checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:2000134 ! negative regulation of G1/S transition of mitotic cell cycle +created_by: jl +creation_date: 2013-11-19T14:31:14Z + +[Term] +id: GO:0044820 +name: mitotic telomere tethering at nuclear periphery +namespace: biological_process +def: "The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle." [GOC:mtg_cell_cycle, PMID:25778919] +is_a: GO:0034398 ! telomere tethering at nuclear periphery +relationship: part_of GO:0120109 ! mitotic telomere clustering and tethering at nuclear periphery +created_by: jl +creation_date: 2013-11-19T16:16:22Z + +[Term] +id: GO:0044821 +name: meiotic telomere tethering at nuclear periphery +namespace: biological_process +def: "The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:0034398 ! telomere tethering at nuclear periphery +is_a: GO:0045141 ! meiotic telomere clustering +created_by: jl +creation_date: 2013-11-19T16:18:09Z + +[Term] +id: GO:0044823 +name: retroviral integrase activity +namespace: molecular_function +def: "Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism." [PMID:19091057] +is_a: GO:0008907 ! integrase activity +relationship: part_of GO:0044826 ! viral genome integration into host DNA +created_by: jl +creation_date: 2014-02-04T14:09:34Z + +[Term] +id: GO:0044824 +name: retroviral 3' processing activity +namespace: molecular_function +def: "The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls." [PMID:22580823, Reactome:R-HSA-164522] +comment: This reaction may serve to remove heterogeneous extra bases from the viral DNA end, and to stabilize the integrase-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification. +synonym: "3' processing reaction" EXACT [] +synonym: "3'-processing activity" EXACT [] +is_a: GO:0004520 ! endodeoxyribonuclease activity +relationship: part_of GO:0044823 ! retroviral integrase activity +created_by: jl +creation_date: 2014-02-04T14:51:24Z + +[Term] +id: GO:0044825 +name: retroviral strand transfer activity +namespace: molecular_function +def: "Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction." [PMID:22580823] +synonym: "strand transfer reaction" EXACT [] +is_a: GO:0140097 ! catalytic activity, acting on DNA +relationship: part_of GO:0044823 ! retroviral integrase activity +created_by: jl +creation_date: 2014-02-04T15:16:39Z + +[Term] +id: GO:0044826 +name: viral genome integration into host DNA +namespace: biological_process +def: "The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses." [PMID:19091057] +synonym: "viral genome integration" EXACT [] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019058 ! viral life cycle +created_by: jl +creation_date: 2014-02-04T16:58:43Z + +[Term] +id: GO:0044827 +name: modulation by host of viral genome replication +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of viral genome replication." [GOC:jl] +synonym: "regulation by host of viral genome reproduction" EXACT [] +is_a: GO:0044788 ! modulation by host of viral process +is_a: GO:0045069 ! regulation of viral genome replication +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: regulates GO:0019079 ! viral genome replication +created_by: jl +creation_date: 2014-02-06T11:26:45Z + +[Term] +id: GO:0044828 +name: negative regulation by host of viral genome replication +namespace: biological_process +def: "A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication." [GOC:jl] +is_a: GO:0044793 ! negative regulation by host of viral process +is_a: GO:0044827 ! modulation by host of viral genome replication +is_a: GO:0045071 ! negative regulation of viral genome replication +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: negatively_regulates GO:0019079 ! viral genome replication +created_by: jl +creation_date: 2014-02-06T11:34:23Z + +[Term] +id: GO:0044829 +name: positive regulation by host of viral genome replication +namespace: biological_process +def: "A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication." [GOC:jl] +is_a: GO:0044794 ! positive regulation by host of viral process +is_a: GO:0044827 ! modulation by host of viral genome replication +is_a: GO:0045070 ! positive regulation of viral genome replication +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: positively_regulates GO:0019079 ! viral genome replication +created_by: jl +creation_date: 2014-02-06T11:35:07Z + +[Term] +id: GO:0044830 +name: modulation by host of viral RNA genome replication +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication." [GOC:jl] +synonym: "regulation by host of viral RNA genome replication" EXACT [] +is_a: GO:0044827 ! modulation by host of viral genome replication +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: regulates GO:0039694 ! viral RNA genome replication +relationship: regulates GO:0039694 ! viral RNA genome replication +created_by: jl +creation_date: 2014-02-06T11:43:16Z + +[Term] +id: GO:0044831 +name: modulation by virus of host cytokine production +namespace: biological_process +def: "Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism." [GOC:jl] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0039656 ! modulation by virus of host gene expression +is_a: GO:0075528 ! modulation by virus of host immune response +intersection_of: GO:0075528 ! modulation by virus of host immune response +intersection_of: regulates GO:0001816 ! cytokine production +created_by: jl +creation_date: 2014-02-06T12:49:02Z + +[Term] +id: GO:0044832 +name: positive regulation by virus of host cytokine production +namespace: biological_process +def: "The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism." [GOC:jl] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0044831 ! modulation by virus of host cytokine production +intersection_of: GO:0075528 ! modulation by virus of host immune response +intersection_of: positively_regulates GO:0001816 ! cytokine production +created_by: jl +creation_date: 2014-02-06T13:04:23Z + +[Term] +id: GO:0044833 +name: modulation by virus of host protein transport +namespace: biological_process +def: "Any viral process that modulates the frequency, rate or extent of protein transport in its host organism." [GOC:jl, PMID:22334672] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:0052038 ! modulation by symbiont of host intracellular transport +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: regulates GO:0015031 ! protein transport +created_by: jl +creation_date: 2014-02-06T13:25:52Z + +[Term] +id: GO:0044834 +name: retroviral intasome +namespace: cellular_component +def: "A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome." [PMID:20118915] +is_a: GO:0032993 ! protein-DNA complex +created_by: jl +creation_date: 2014-02-06T14:33:39Z + +[Term] +id: GO:0044835 +name: hydrogen generation via nitrogenase +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria." [GOC:mengo_curators, PMID:22128188] +is_a: GO:1902422 ! hydrogen biosynthetic process +intersection_of: GO:1902422 ! hydrogen biosynthetic process +intersection_of: has_part GO:0016163 ! nitrogenase activity +relationship: has_part GO:0016163 ! nitrogenase activity +created_by: jl +creation_date: 2014-02-19T14:59:15Z + +[Term] +id: GO:0044836 +name: D-xylose fermentation +namespace: biological_process +def: "The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP." [GOC:mengo_curators] +is_a: GO:0006113 ! fermentation +is_a: GO:0044577 ! xylose catabolic process to ethanol +created_by: jl +creation_date: 2014-02-19T16:14:57Z + +[Term] +id: GO:0044837 +name: actomyosin contractile ring organization +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring." [GOC:mtg_cell_cycle] +synonym: "cytokinesis, actomyosin contractile ring organization" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0030866 ! cortical actin cytoskeleton organization +is_a: GO:0031032 ! actomyosin structure organization +relationship: part_of GO:0061640 ! cytoskeleton-dependent cytokinesis +created_by: jl +creation_date: 2014-02-26T15:31:31Z + +[Term] +id: GO:0044838 +name: cell quiescence +namespace: biological_process +def: "A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed." [GOC:jb, GOC:mah] +comment: Note that terminally differentiated cells in higher eukaryotes are typically quiescent but metabolically active. Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "cell cycle quiescence" RELATED [GOC:mah] +synonym: "cellular quiescence" EXACT [GOC:mah] +synonym: "G0 phase" RELATED [GOC:mah] +synonym: "quiescence" BROAD [GOC:mah] +is_a: GO:0022403 ! cell cycle phase +created_by: jl +creation_date: 2014-02-26T16:15:51Z + +[Term] +id: GO:0044839 +name: cell cycle G2/M phase transition +namespace: biological_process +def: "The cell cycle process by which a cell in G2 phase commits to M phase." [GOC:jl, GOC:mtg_cell_cycle] +is_a: GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2014-03-05T14:56:45Z + +[Term] +id: GO:0044840 +name: gut granule +namespace: cellular_component +def: "A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage." [GOC:kmv, PMID:22916203, PMID:24204312] +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: jl +creation_date: 2014-03-25T11:56:41Z + +[Term] +id: GO:0044841 +name: gut granule membrane +namespace: cellular_component +def: "The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." [GOC:kmv, PMID:22916203, PMID:24204312] +is_a: GO:0031090 ! organelle membrane +intersection_of: GO:0031090 ! organelle membrane +intersection_of: part_of GO:0044840 ! gut granule +relationship: part_of GO:0044840 ! gut granule +created_by: jl +creation_date: 2014-03-25T12:02:05Z + +[Term] +id: GO:0044842 +name: gut granule lumen +namespace: cellular_component +def: "The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." [GOC:kmv, PMID:22916203, PMID:24204312] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0043233 ! organelle lumen +intersection_of: part_of GO:0044840 ! gut granule +relationship: part_of GO:0044840 ! gut granule +created_by: jl +creation_date: 2014-03-25T12:02:32Z + +[Term] +id: GO:0044843 +name: cell cycle G1/S phase transition +namespace: biological_process +def: "The cell cycle process by which a cell in G1 phase commits to S phase." [GOC:mtg_cell_cycle] +is_a: GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2014-03-25T16:33:47Z + +[Term] +id: GO:0044844 +name: meiotic interphase II +namespace: biological_process +def: "The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge." [GOC:jl, GOC:mtg_cell_cycle] +comment: note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0051328 ! meiotic interphase +is_a: GO:0098765 ! meiosis II cell cycle phase +created_by: jl +creation_date: 2014-03-26T16:52:27Z + +[Term] +id: GO:0044845 +name: chain elongation of O-linked mannose residue +namespace: biological_process +def: "Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules." [GOC:jl, PMID:19429925] +comment: Example annotations to this term include the S. cerevisiae alpha1,2-mannosyltransferases ScKre2p, ScKtr1p and ScKtr3pof the KTR family. +is_a: GO:0035268 ! protein mannosylation +created_by: jl +creation_date: 2014-05-08T15:56:39Z + +[Term] +id: GO:0044846 +name: negative regulation by symbiont of indole acetic acid levels in host +namespace: biological_process +def: "Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:18056646] +synonym: "negative regulation by symbiont of auxin levels in host" EXACT [] +synonym: "negative regulation by symbiont of IAA levels in host" EXACT [] +is_a: GO:0044032 ! modulation by symbiont of indole acetic acid levels in host +created_by: jl +creation_date: 2014-05-13T11:08:04Z + +[Term] +id: GO:0044847 +name: iron acquisition from host +namespace: biological_process +alt_id: GO:0052099 +def: "The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell." [PMID:15487950, PMID:22865843] +synonym: "acquisition by organism of nutrients from host via siderophores" RELATED [] +synonym: "acquisition by symbiont of nutrients from host via siderophores" NARROW [] +synonym: "heme acquisition" RELATED [] +synonym: "iron acquisition" BROAD [] +synonym: "iron acquisition by symbiont from host" EXACT [] +synonym: "iron acquisition by symbiont from host heme" NARROW [] +is_a: GO:0044002 ! acquisition of nutrients from host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17896 xsd:anyURI +created_by: jl +creation_date: 2014-05-13T13:40:59Z + +[Term] +id: GO:0044848 +name: biological phase +namespace: biological_process +def: "A distinct period or stage in a biological process or cycle." [GOC:jl] +comment: Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase. +subset: gocheck_do_not_manually_annotate +is_a: GO:0008150 ! biological_process +disjoint_from: GO:0046879 ! hormone secretion +disjoint_from: GO:0048511 ! rhythmic process +disjoint_from: GO:0050896 ! response to stimulus +disjoint_from: GO:0051179 ! localization +disjoint_from: GO:0051704 ! multi-organism process +disjoint_from: GO:0071840 ! cellular component organization or biogenesis +disjoint_from: GO:0098743 ! cell aggregation +created_by: jl +creation_date: 2014-07-16T13:12:40Z + +[Term] +id: GO:0044849 +name: estrous cycle +namespace: biological_process +def: "A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur." [GOC:jl, Wikipedia:Estrous_cycle] +xref: Wikipedia:Estrous_cycle +is_a: GO:0042698 ! ovulation cycle +created_by: jl +creation_date: 2014-07-16T13:41:42Z + +[Term] +id: GO:0044850 +name: menstrual cycle +namespace: biological_process +def: "A type of ovulation cycle where the endometrium is shed if pregnancy does not occur." [GOC:jl] +xref: Wikipedia:Menstrual_cycle +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0042698 ! ovulation cycle +created_by: jl +creation_date: 2014-07-16T13:51:29Z + +[Term] +id: GO:0044851 +name: hair cycle phase +namespace: biological_process +def: "The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body." [GOC:jl] +subset: gocheck_do_not_annotate +is_a: GO:0044848 ! biological phase +created_by: jl +creation_date: 2014-07-16T14:22:09Z + +[Term] +id: GO:0044852 +name: nonrepetitive DNA condensation +namespace: biological_process +def: "The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells." [GOC:jl, PMID:10811823] +synonym: "nonrepetitive DNA packaging" EXACT [] +is_a: GO:0006323 ! DNA packaging +relationship: part_of GO:0030261 ! chromosome condensation +created_by: jl +creation_date: 2014-07-17T14:13:23Z + +[Term] +id: GO:0044853 +name: plasma membrane raft +namespace: cellular_component +def: "A membrane raft that is part of the plasma membrane." [GOC:jl] +is_a: GO:0045121 ! membrane raft +is_a: GO:0098590 ! plasma membrane region +intersection_of: GO:0045121 ! membrane raft +intersection_of: part_of GO:0005886 ! plasma membrane +created_by: jl +creation_date: 2014-07-23T15:55:23Z + +[Term] +id: GO:0044854 +name: plasma membrane raft assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft." [GOC:jl] +is_a: GO:0001765 ! membrane raft assembly +is_a: GO:0044857 ! plasma membrane raft organization +created_by: jl +creation_date: 2014-07-23T15:58:16Z + +[Term] +id: GO:0044855 +name: plasma membrane raft distribution +namespace: biological_process +def: "The process that establishes the spatial arrangement of membrane rafts within a plasma membrane." [GOC:jl] +is_a: GO:0031580 ! membrane raft distribution +is_a: GO:0044856 ! plasma membrane raft localization +created_by: jl +creation_date: 2014-07-23T16:00:41Z + +[Term] +id: GO:0044856 +name: plasma membrane raft localization +namespace: biological_process +def: "Any process in which plasma membrane rafts are transported to, or maintained in, a specific location." [GOC:jl] +is_a: GO:0007009 ! plasma membrane organization +is_a: GO:0051665 ! membrane raft localization +created_by: jl +creation_date: 2014-07-23T16:12:22Z + +[Term] +id: GO:0044857 +name: plasma membrane raft organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts." [GOC:jl] +is_a: GO:0031579 ! membrane raft organization +relationship: part_of GO:0007009 ! plasma membrane organization +created_by: jl +creation_date: 2014-07-23T16:20:07Z + +[Term] +id: GO:0044858 +name: plasma membrane raft polarization +namespace: biological_process +def: "The clustering and aggregation of plasma membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes." [GOC:jl] +is_a: GO:0001766 ! membrane raft polarization +is_a: GO:0044855 ! plasma membrane raft distribution +created_by: jl +creation_date: 2014-07-23T16:21:39Z + +[Term] +id: GO:0044859 +name: protein insertion into plasma membrane raft +namespace: biological_process +def: "The process in which a protein is incorporated into a plasma membrane raft." [GOC:jl] +is_a: GO:0044860 ! protein localization to plasma membrane raft +is_a: GO:0071210 ! protein insertion into membrane raft +is_a: GO:0098737 ! protein insertion into plasma membrane +created_by: jl +creation_date: 2014-07-23T16:23:20Z + +[Term] +id: GO:0044860 +name: protein localization to plasma membrane raft +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft." [GOC:jl] +is_a: GO:1903044 ! protein localization to membrane raft +is_a: GO:1990778 ! protein localization to cell periphery +created_by: jl +creation_date: 2014-07-23T16:25:01Z + +[Term] +id: GO:0044861 +name: protein transport into plasma membrane raft +namespace: biological_process +def: "The directed movement of a protein into a plasma membrane raft." [GOC:jl] +is_a: GO:0032596 ! protein transport into membrane raft +is_a: GO:0044860 ! protein localization to plasma membrane raft +created_by: jl +creation_date: 2014-07-23T16:26:29Z + +[Term] +id: GO:0044862 +name: protein transport out of plasma membrane raft +namespace: biological_process +def: "The directed movement of a protein out of a plasma membrane raft." [GOC:jl] +is_a: GO:0032599 ! protein transport out of membrane raft +is_a: GO:0090150 ! establishment of protein localization to membrane +is_a: GO:0099632 ! protein transport within plasma membrane +is_a: GO:1990778 ! protein localization to cell periphery +created_by: jl +creation_date: 2014-07-23T16:32:56Z + +[Term] +id: GO:0044863 +name: modulation by virus of host cell division +namespace: biological_process +def: "Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells." [GOC:jl] +synonym: "regulation by virus of host cell division" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0051302 ! regulation of cell division +created_by: jl +creation_date: 2014-08-05T16:30:03Z + +[Term] +id: GO:0044864 +name: positive regulation by virus of host cell division +namespace: biological_process +def: "Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division." [GOC:jl] +is_a: GO:0044863 ! modulation by virus of host cell division +is_a: GO:0051781 ! positive regulation of cell division +created_by: jl +creation_date: 2014-08-05T16:31:20Z + +[Term] +id: GO:0044865 +name: negative regulation by virus of host cell division +namespace: biological_process +def: "Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division." [GOC:jl] +synonym: "inhibition by virus of host cell division" NARROW [] +is_a: GO:0044863 ! modulation by virus of host cell division +is_a: GO:0051782 ! negative regulation of cell division +created_by: jl +creation_date: 2014-08-05T16:31:44Z + +[Term] +id: GO:0044866 +name: modulation by host of viral exo-alpha-sialidase activity +namespace: biological_process +def: "The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein." [GOC:jl] +is_a: GO:0044867 ! modulation by host of viral catalytic activity +is_a: GO:1903015 ! regulation of exo-alpha-sialidase activity +intersection_of: GO:0044867 ! modulation by host of viral catalytic activity +intersection_of: regulates GO:0004308 ! exo-alpha-sialidase activity +created_by: jl +creation_date: 2014-09-18T11:28:18Z + +[Term] +id: GO:0044867 +name: modulation by host of viral catalytic activity +namespace: biological_process +def: "The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected." [GOC:jl] +is_a: GO:0044868 ! modulation by host of viral molecular function +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0044868 ! modulation by host of viral molecular function +intersection_of: regulates GO:0003824 ! catalytic activity +created_by: jl +creation_date: 2014-09-18T11:29:25Z + +[Term] +id: GO:0044868 +name: modulation by host of viral molecular function +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected." [GOC:jl] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0044788 ! modulation by host of viral process +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: negatively_regulates GO:0003674 ! molecular_function +created_by: jl +creation_date: 2014-09-18T13:34:27Z + +[Term] +id: GO:0044869 +name: negative regulation by host of viral exo-alpha-sialidase activity +namespace: biological_process +def: "The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein." [GOC:jl] +is_a: GO:0044866 ! modulation by host of viral exo-alpha-sialidase activity +is_a: GO:0052403 ! negative regulation by host of symbiont catalytic activity +is_a: GO:1903016 ! negative regulation of exo-alpha-sialidase activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: negatively_regulates GO:0004308 ! exo-alpha-sialidase activity +created_by: jl +creation_date: 2014-09-18T14:13:51Z + +[Term] +id: GO:0044870 +name: modulation by host of viral glycoprotein metabolic process +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process." [GOC:jl] +is_a: GO:0044788 ! modulation by host of viral process +is_a: GO:1903018 ! regulation of glycoprotein metabolic process +intersection_of: GO:0044788 ! modulation by host of viral process +intersection_of: regulates GO:0009100 ! glycoprotein metabolic process +created_by: jl +creation_date: 2014-09-18T14:26:19Z + +[Term] +id: GO:0044871 +name: negative regulation by host of viral glycoprotein metabolic process +namespace: biological_process +def: "A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process." [GOC:jl] +is_a: GO:0044793 ! negative regulation by host of viral process +is_a: GO:0044870 ! modulation by host of viral glycoprotein metabolic process +is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process +intersection_of: GO:0048525 ! negative regulation of viral process +intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process +created_by: jl +creation_date: 2014-09-18T14:28:48Z + +[Term] +id: GO:0044872 +name: lipoprotein localization +namespace: biological_process +def: "Any process in which a lipoprotein is transported to, or maintained in, a specific location." [GOC:jl] +is_a: GO:0008104 ! protein localization +created_by: jl +creation_date: 2014-11-25T16:27:06Z + +[Term] +id: GO:0044873 +name: lipoprotein localization to membrane +namespace: biological_process +def: "A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane." [GOC:jl] +is_a: GO:0044872 ! lipoprotein localization +is_a: GO:0072657 ! protein localization to membrane +created_by: jl +creation_date: 2014-11-25T16:28:43Z + +[Term] +id: GO:0044874 +name: lipoprotein localization to outer membrane +namespace: biological_process +def: "A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane." [GOC:jl] +is_a: GO:0044873 ! lipoprotein localization to membrane +created_by: jl +creation_date: 2014-11-25T16:30:30Z + +[Term] +id: GO:0044875 +name: gamma-glutamyl hercynylcysteine sulfoxide synthase +namespace: molecular_function +def: "Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O." [GOC:jl, PMID:24828577] +synonym: "gamma-glutamyl hercynylcysteine S-oxide synthase" EXACT [GOC:dph] +xref: EC:1.14.99 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: jl +creation_date: 2014-12-15T11:44:54Z + +[Term] +id: GO:0044876 +name: hercynylselenocysteine synthase +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine." [GOC:jl, PMID:24828577] +xref: MetaCyc:RXN-15803 +xref: RHEA:42683 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: jl +creation_date: 2014-12-15T11:56:12Z + +[Term] +id: GO:0044877 +name: protein-containing complex binding +namespace: molecular_function +alt_id: GO:0032403 +def: "Interacting selectively and non-covalently with a macromolecular complex." [GOC:jl] +subset: goslim_chembl +synonym: "macromolecular complex binding" RELATED [] +synonym: "protein complex binding" EXACT [] +is_a: GO:0005488 ! binding +created_by: jl +creation_date: 2014-12-16T11:38:58Z + +[Term] +id: GO:0044878 +name: mitotic cytokinesis checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed." [GOC:jl, GOC:mtg_cell_cycle, PMID:17538026] +synonym: "cytokinesis after mitosis checkpoint" RELATED [GOC:dph, GOC:vw] +synonym: "defective cytokinesis checkpoint" RELATED [GOC:dph, GOC:vw] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:0010972 ! negative regulation of G2/M transition of mitotic cell cycle +created_by: jl +creation_date: 2015-01-13T15:30:23Z + +[Term] +id: GO:0044879 +name: morphogenesis checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth." [GOC:jl, GOC:mtg_cell_cycle] +synonym: "septin checkpoint" EXACT [] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +created_by: jl +creation_date: 2015-01-13T16:03:07Z + +[Term] +id: GO:0045002 +name: double-strand break repair via single-strand annealing +namespace: biological_process +def: "Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats." [PMID:11606529] +is_a: GO:0000726 ! non-recombinational repair +is_a: GO:0006302 ! double-strand break repair + +[Term] +id: GO:0045003 +name: double-strand break repair via synthesis-dependent strand annealing +namespace: biological_process +def: "SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break." [PMID:10357855] +synonym: "mitotic gene conversion" RELATED [] +synonym: "SDSA" BROAD [] +is_a: GO:0000724 ! double-strand break repair via homologous recombination + +[Term] +id: GO:0045004 +name: DNA replication proofreading +namespace: biological_process +def: "Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity." [GOC:ai] +is_a: GO:0006281 ! DNA repair +is_a: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity + +[Term] +id: GO:0045005 +name: DNA-dependent DNA replication maintenance of fidelity +namespace: biological_process +def: "A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair." [GOC:mah, GOC:vw] +synonym: "maintenance of fidelity during DNA-dependent DNA replication" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of fidelity involved in DNA-dependent DNA replication" EXACT [] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0045006 +name: DNA deamination +namespace: biological_process +def: "The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil." [GOC:ai] +is_a: GO:0006304 ! DNA modification + +[Term] +id: GO:0045007 +name: depurination +namespace: biological_process +def: "The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar." [GOC:ai] +xref: Wikipedia:Depurination +is_a: GO:0006285 ! base-excision repair, AP site formation +is_a: GO:0006304 ! DNA modification + +[Term] +id: GO:0045008 +name: depyrimidination +namespace: biological_process +def: "The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar." [GOC:ai] +is_a: GO:0006285 ! base-excision repair, AP site formation +is_a: GO:0006304 ! DNA modification +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process + +[Term] +id: GO:0045009 +name: chitosome +namespace: cellular_component +def: "An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum." [ISBN:0198506732, PMID:8970154] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0045010 +name: actin nucleation +namespace: biological_process +def: "The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament." [ISBN:0815316194] +synonym: "actin filament nucleation" EXACT [] +is_a: GO:0007015 ! actin filament organization +is_a: GO:0030838 ! positive regulation of actin filament polymerization + +[Term] +id: GO:0045012 +name: obsolete MHC class II receptor activity +namespace: molecular_function +def: "OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes." [ISBN:081533642X, ISBN:0879694971] +comment: This term was made obsolete because it was defined ambiguously, and has therefore been used incorrectly in annotations. To update annotations of gene products that act as receptors for MHC class II protein complexes, use the molecular function term 'MHC class II receptor activity ; GO:0032395'; to update annotations of gene products which are components of MHC class II protein complexes, use the cellular component term 'MHC class II protein complex ; GO:0042613'. +synonym: "class II major histocompatibility complex antigen" RELATED [] +synonym: "major histocompatibility complex class II receptor" EXACT [] +synonym: "MHC class II receptor activity" EXACT [] +is_obsolete: true +consider: GO:0032395 +consider: GO:0042613 + +[Term] +id: GO:0045013 +name: carbon catabolite repression of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances." [GOC:mah, ISBN:0198506732, PMID:11018147, PMID:18359269, PMID:9618445] +synonym: "carbon catabolite repression" RELATED [GOC:dph] +synonym: "negative regulation of transcription by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:0045990 ! carbon catabolite regulation of transcription +is_a: GO:0061985 ! carbon catabolite repression + +[Term] +id: GO:0045014 +name: carbon catabolite repression of transcription by glucose +namespace: biological_process +def: "A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances." [ISBN:0198506732, PMID:11018147] +synonym: "down regulation of transcription by glucose" EXACT [] +synonym: "down-regulation of transcription by glucose" EXACT [] +synonym: "downregulation of transcription by glucose" EXACT [] +synonym: "glucose effect" EXACT [] +synonym: "glucose repression" EXACT [] +synonym: "inhibition of transcription by glucose" NARROW [] +is_a: GO:0045013 ! carbon catabolite repression of transcription +is_a: GO:0061986 ! negative regulation of transcription by glucose + +[Term] +id: GO:0045015 +name: HDEL sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [PMID:1327759] +synonym: "HDEL receptor activity" NARROW [] +is_a: GO:0046923 ! ER retention sequence binding + +[Term] +id: GO:0045016 +name: mitochondrial magnesium ion transmembrane transport +namespace: biological_process +alt_id: GO:1990614 +def: "The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:ai, PMID:11254124] +synonym: "mitochondrial magnesium ion transport" RELATED [] +is_a: GO:1903830 ! magnesium ion transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: mcc +creation_date: 2015-01-21T17:44:38Z + +[Term] +id: GO:0045017 +name: glycerolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone." [GOC:ai] +synonym: "glycerolipid anabolism" EXACT [] +synonym: "glycerolipid biosynthesis" EXACT [] +synonym: "glycerolipid formation" EXACT [] +synonym: "glycerolipid synthesis" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0046486 ! glycerolipid metabolic process + +[Term] +id: GO:0045018 +name: retrograde transport, vacuole to Golgi +namespace: biological_process +def: "The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment." [PMID:9700156] +synonym: "retrograde transport from the vacuole" EXACT [] +is_a: GO:0007034 ! vacuolar transport + +[Term] +id: GO:0045019 +name: negative regulation of nitric oxide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] +synonym: "down regulation of nitric oxide biosynthetic process" EXACT [] +synonym: "down-regulation of nitric oxide biosynthetic process" EXACT [] +synonym: "downregulation of nitric oxide biosynthetic process" EXACT [] +synonym: "inhibition of nitric oxide biosynthetic process" NARROW [] +synonym: "negative regulation of nitric oxide anabolism" EXACT [] +synonym: "negative regulation of nitric oxide biosynthesis" EXACT [] +synonym: "negative regulation of nitric oxide formation" EXACT [] +synonym: "negative regulation of nitric oxide synthesis" EXACT [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process +is_a: GO:1903427 ! negative regulation of reactive oxygen species biosynthetic process +is_a: GO:1904406 ! negative regulation of nitric oxide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006809 ! nitric oxide biosynthetic process +relationship: negatively_regulates GO:0006809 ! nitric oxide biosynthetic process + +[Term] +id: GO:0045020 +name: obsolete error-prone DNA repair +namespace: biological_process +def: "OBSOLETE. DNA repair pathways that tend to increase the endogenous mutation rate." [GOC:jl, PMID:11459974] +comment: This term was made obsolete because 'error-prone' does not correspond to a repair mechanism, and the term has been superseded by more specific terms. +synonym: "error-prone DNA repair" EXACT [] +synonym: "mutagenic DNA repair" EXACT [] +is_obsolete: true +consider: GO:0042276 + +[Term] +id: GO:0045021 +name: obsolete error-free DNA repair +namespace: biological_process +def: "OBSOLETE. DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways." [GOC:jl, PMID:11459974] +comment: This term was made obsolete because 'error-free' does not correspond to a repair mechanism, and the term has been superseded by more specific terms. +synonym: "error-free DNA repair" EXACT [] +is_obsolete: true +consider: GO:0042275 +consider: GO:0070987 + +[Term] +id: GO:0045022 +name: early endosome to late endosome transport +namespace: biological_process +def: "The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs." [ISBN:0815316194] +is_a: GO:0016482 ! cytosolic transport +is_a: GO:0098927 ! vesicle-mediated transport between endosomal compartments + +[Term] +id: GO:0045023 +name: G0 to G1 transition +namespace: biological_process +def: "The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression." [GOC:mtg_cell_cycle, ISBN:0716731363] +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0045024 +name: obsolete peptidyl-glutamyl peptide hydrolyzing enzyme activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids." [PMID:11735414] +comment: This term was made obsolete because it represents a gene product. +synonym: "peptidyl-glutamyl peptide hydrolyzing enzyme activity" EXACT [] +is_obsolete: true +replaced_by: GO:0070011 + +[Term] +id: GO:0045025 +name: mitochondrial degradosome +namespace: cellular_component +def: "A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer." [PMID:10397341, PMID:9829834] +synonym: "mtEXO" EXACT [PMID:10397341, PMID:9829834] +is_a: GO:0000177 ! cytoplasmic exosome (RNase complex) +is_a: GO:0098798 ! mitochondrial protein complex + +[Term] +id: GO:0045026 +name: plasma membrane fusion +namespace: biological_process +alt_id: GO:0006947 +def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle] +synonym: "cell fusion" BROAD [] +synonym: "cell-cell fusion" BROAD [] +is_a: GO:0061025 ! membrane fusion + +[Term] +id: GO:0045027 +name: DNA end binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the ends of DNA that are exposed by the creation of double-strand breaks (DSBs)." [GOC:jl] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0045028 +name: G protein-coupled purinergic nucleotide receptor activity +namespace: molecular_function +def: "Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah, PMID:9755289] +synonym: "G protein coupled purinergic nucleotide receptor activity" EXACT [] +synonym: "G-protein coupled purinergic nucleotide receptor activity" EXACT [] +synonym: "P2Y" RELATED [] +synonym: "P2Y receptor" RELATED [PMID:9755289] +synonym: "purinergic nucleotide receptor activity, G protein coupled" EXACT [] +synonym: "purinergic nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0001614 ! purinergic nucleotide receptor activity +is_a: GO:0004930 ! G protein-coupled receptor activity +relationship: part_of GO:0035589 ! G protein-coupled purinergic nucleotide receptor signaling pathway + +[Term] +id: GO:0045029 +name: G protein-coupled UDP receptor activity +namespace: molecular_function +def: "Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP." [GOC:mah] +synonym: "UDP-activated nucleotide receptor activity" BROAD [] +is_a: GO:0071553 ! G protein-coupled pyrimidinergic nucleotide receptor activity + +[Term] +id: GO:0045030 +name: G protein-coupled UTP receptor activity +namespace: molecular_function +alt_id: GO:0015065 +def: "Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP." [GOC:mah] +synonym: "purinoceptor type U" BROAD [] +synonym: "uridine nucleotide receptor activity" BROAD [] +synonym: "UTP-activated nucleotide receptor activity" BROAD [] +is_a: GO:0071553 ! G protein-coupled pyrimidinergic nucleotide receptor activity + +[Term] +id: GO:0045031 +name: G protein-coupled ATP receptor activity +namespace: molecular_function +def: "Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:mah] +synonym: "ATP-activated adenosine receptor activity" RELATED [] +synonym: "ATP-activated nucleotide receptor activity" BROAD [] +is_a: GO:0045028 ! G protein-coupled purinergic nucleotide receptor activity + +[Term] +id: GO:0045033 +name: peroxisome inheritance +namespace: biological_process +def: "The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p." [PMID:11733545] +comment: Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another. +is_a: GO:0007031 ! peroxisome organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0045034 +name: obsolete neuroblast division +namespace: biological_process +alt_id: GO:0043345 +alt_id: GO:0043346 +def: "OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell." [PMID:11163136, PMID:11250167] +comment: This term was made obsolete because the definition was incorrect. Not all neuroblasts divide asymmetrically. Neuroblasts give rise to neurons after division. +synonym: "neuroblast cell division" EXACT [] +synonym: "neuroblast division" EXACT [] +synonym: "neuroblast division (sensu Nematoda and Protostomia)" EXACT [] +synonym: "neuroblast division (sensu Vertebrata)" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045035 +name: sensory organ precursor cell division +namespace: biological_process +def: "The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron)." [GOC:mah, PMID:11171389, PMID:18295597] +synonym: "sense organ precursor cell division" EXACT [GOC:dph] +is_a: GO:0008356 ! asymmetric cell division +relationship: part_of GO:0007423 ! sensory organ development + +[Term] +id: GO:0045036 +name: protein targeting to chloroplast +namespace: biological_process +def: "The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved." [ISBN:0716731363] +synonym: "protein-chloroplast targeting" EXACT [] +is_a: GO:0006605 ! protein targeting +is_a: GO:0072596 ! establishment of protein localization to chloroplast + +[Term] +id: GO:0045037 +name: protein import into chloroplast stroma +namespace: biological_process +def: "The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import." [ISBN:0716731363] +synonym: "chloroplast stroma protein import" EXACT [] +synonym: "protein transport into chloroplast stroma" EXACT [] +is_a: GO:0017038 ! protein import +is_a: GO:0045036 ! protein targeting to chloroplast +is_a: GO:0065002 ! intracellular protein transmembrane transport + +[Term] +id: GO:0045038 +name: protein import into chloroplast thylakoid membrane +namespace: biological_process +def: "The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma." [ISBN:0716731363] +synonym: "chloroplast thylakoid membrane protein import" EXACT [] +synonym: "protein transport into chloroplast thylakoid membrane" EXACT [] +is_a: GO:0006612 ! protein targeting to membrane +is_a: GO:0044743 ! protein transmembrane import into intracellular organelle +is_a: GO:0045036 ! protein targeting to chloroplast +is_a: GO:0065002 ! intracellular protein transmembrane transport + +[Term] +id: GO:0045039 +name: protein insertion into mitochondrial inner membrane +namespace: biological_process +def: "The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane." [GOC:mcc, GOC:vw, PMID:18672008] +synonym: "mitochondrial inner membrane protein import" EXACT [] +synonym: "protein import into mitochondrial inner membrane" EXACT [] +synonym: "protein transport into mitochondrial inner membrane" EXACT [] +is_a: GO:0007007 ! inner mitochondrial membrane organization +is_a: GO:0051204 ! protein insertion into mitochondrial membrane +relationship: part_of GO:0006626 ! protein targeting to mitochondrion +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15800 xsd:anyURI + +[Term] +id: GO:0045040 +name: protein insertion into mitochondrial outer membrane +namespace: biological_process +def: "The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes." [GOC:mcc, GOC:vw, PMID:18672008] +synonym: "mitochondrial outer membrane protein import" EXACT [] +synonym: "protein import into mitochondrial outer membrane" EXACT [] +synonym: "protein transport into mitochondrial outer membrane" EXACT [] +is_a: GO:0007008 ! outer mitochondrial membrane organization +is_a: GO:0017038 ! protein import +is_a: GO:0051204 ! protein insertion into mitochondrial membrane +relationship: part_of GO:0006626 ! protein targeting to mitochondrion + +[Term] +id: GO:0045041 +name: protein import into mitochondrial intermembrane space +namespace: biological_process +alt_id: GO:0045043 +alt_id: GO:0045044 +def: "The import of proteins into the space between the inner and outer mitochondrial membranes." [ISBN:0716731363] +synonym: "mitochondrial intermembrane space protein import" EXACT [] +synonym: "protein import into mitochondrial IMS" EXACT [] +synonym: "protein import into mitochondrial intermembrane space, direct" NARROW [GOC:mcc] +synonym: "protein import into mitochondrial intermembrane space, nonconservative" NARROW [GOC:mcc] +synonym: "protein transport into mitochondrial IMS" EXACT [] +synonym: "protein transport into mitochondrial intermembrane space" EXACT [] +is_a: GO:0044743 ! protein transmembrane import into intracellular organelle +is_a: GO:0065002 ! intracellular protein transmembrane transport +is_a: GO:0072655 ! establishment of protein localization to mitochondrion +is_a: GO:1990542 ! mitochondrial transmembrane transport +relationship: part_of GO:0006626 ! protein targeting to mitochondrion + +[Term] +id: GO:0045042 +name: obsolete protein import into mitochondrial intermembrane space, conservative +namespace: biological_process +def: "OBSOLETE. The conservative import of proteins into the mitochondrial intermembrane space. The entire protein enters the matrix, and then the second targeting sequence directs the protein, presumably bound to a matrix protein, across the inner membrane to the intermembrane space." [ISBN:0716731363] +comment: This term was made obsolete because there is no 'conservative' process of protein import into the mitochondrial intermembrane space that is distinct from the more general parent; furthermore, 'conservative' is used in the literature to describe a pathway of import into the inner membrane rather than into the intermembrane space. +synonym: "conservative mitochondrial IMS protein import" EXACT [] +synonym: "conservative mitochondrial intermembrane space protein import" EXACT [] +synonym: "conservative protein transport into mitochondrial IMS" EXACT [] +synonym: "conservative protein transport into mitochondrial intermembrane space" EXACT [] +synonym: "protein import into mitochondrial IMS, conservative" EXACT [] +synonym: "protein import into mitochondrial intermembrane space, conservative" EXACT [] +synonym: "protein transport into mitochondrial IMS, conservative" EXACT [] +synonym: "protein transport into mitochondrial intermembrane space, conservative" EXACT [] +is_obsolete: true +consider: GO:0045039 +consider: GO:0045041 + +[Term] +id: GO:0045045 +name: obsolete secretory pathway +namespace: biological_process +def: "OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane." [ISBN:0716731363] +comment: This term was made obsolete because it artificially groups a number of other terms, leading to path problems, its definition is unclear (and lacks genus-differentia features), and it has probably been used incorrectly in annotations. +synonym: "secretory pathway" EXACT [] +is_obsolete: true +replaced_by: GO:0032940 + +[Term] +id: GO:0045046 +name: protein import into peroxisome membrane +namespace: biological_process +def: "The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import." [ISBN:0716731363, PMID:11687502] +synonym: "peroxisome membrane protein import" EXACT [] +synonym: "protein transport into peroxisome membrane" EXACT [] +is_a: GO:0006612 ! protein targeting to membrane +is_a: GO:0006625 ! protein targeting to peroxisome +is_a: GO:0015919 ! peroxisomal membrane transport +is_a: GO:0017038 ! protein import + +[Term] +id: GO:0045047 +name: protein targeting to ER +namespace: biological_process +def: "The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane." [ISBN:0716731363] +synonym: "protein targeting to endoplasmic reticulum" EXACT [] +synonym: "protein-endoplasmic reticulum targeting" EXACT [] +synonym: "protein-ER targeting" EXACT [] +is_a: GO:0006605 ! protein targeting +is_a: GO:0072599 ! establishment of protein localization to endoplasmic reticulum + +[Term] +id: GO:0045048 +name: protein insertion into ER membrane +namespace: biological_process +def: "The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane." [ISBN:0716731363] +synonym: "integral ER membrane protein localization" EXACT [] +synonym: "integral ER membrane protein positioning" EXACT [] +synonym: "localization of protein in ER membrane" EXACT [] +synonym: "positioning of protein in ER membrane" EXACT [] +synonym: "protein insertion into endoplasmic reticulum membrane" EXACT [] +synonym: "protein-endoplasmic reticulum insertion" EXACT [] +synonym: "protein-ER insertion" EXACT [] +is_a: GO:0051205 ! protein insertion into membrane +relationship: part_of GO:0007029 ! endoplasmic reticulum organization +relationship: part_of GO:0033365 ! protein localization to organelle + +[Term] +id: GO:0045049 +name: protein insertion into ER membrane by N-terminal cleaved signal sequence +namespace: biological_process +def: "A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER." [ISBN:0716731363] +synonym: "N-terminal cleaved signal sequence mediated protein insertion into ER membrane" EXACT [] +synonym: "protein insertion into endoplasmic reticulum membrane by N-terminal cleaved signal sequence" EXACT [] +synonym: "protein insertion into ER membrane, N-terminal cleaved signal sequence mediated" EXACT [] +synonym: "protein-endoplasmic reticulum insertion by N-terminal cleaved signal sequence" EXACT [] +synonym: "protein-ER insertion by N-terminal cleaved signal sequence" EXACT [] +is_a: GO:0045048 ! protein insertion into ER membrane + +[Term] +id: GO:0045050 +name: protein insertion into ER membrane by stop-transfer membrane-anchor sequence +namespace: biological_process +def: "A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix." [ISBN:0716731363] +synonym: "protein insertion into endoplasmic reticulum membrane by stop-transfer membrane-anchor sequence" EXACT [] +synonym: "protein insertion into ER membrane, stop-transfer membrane-anchor sequence mediated" EXACT [] +synonym: "protein-endoplasmic reticulum insertion by stop-transfer membrane-anchor sequence" EXACT [] +synonym: "protein-ER insertion by stop-transfer membrane-anchor sequence" EXACT [] +synonym: "stop-transfer membrane-anchor sequence mediated protein insertion into ER membrane" EXACT [] +is_a: GO:0045048 ! protein insertion into ER membrane + +[Term] +id: GO:0045051 +name: protein insertion into ER membrane by internal uncleaved signal-anchor sequence +namespace: biological_process +def: "A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences." [ISBN:0716731363] +synonym: "internal uncleaved signal-anchor sequence mediated protein insertion into ER membrane" EXACT [] +synonym: "protein insertion into endoplasmic reticulum membrane by internal uncleaved signal-anchor sequence" EXACT [] +synonym: "protein insertion into ER membrane, internal uncleaved signal-anchor sequence mediated" EXACT [] +synonym: "protein-endoplasmic reticulum insertion by internal uncleaved signal-anchor sequence" EXACT [] +synonym: "protein-ER insertion by internal uncleaved signal-anchor sequence" EXACT [] +is_a: GO:0045048 ! protein insertion into ER membrane + +[Term] +id: GO:0045052 +name: protein insertion into ER membrane by GPI attachment sequence +namespace: biological_process +def: "A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule." [ISBN:0716731363] +synonym: "GPI attachment sequence mediated protein insertion into ER membrane" EXACT [] +synonym: "protein insertion into endoplasmic reticulum membrane by GPI attachment sequence" EXACT [] +synonym: "protein insertion into ER membrane, GPI attachment sequence mediated" EXACT [] +synonym: "protein-endoplasmic reticulum insertion by GPI attachment sequence" EXACT [] +synonym: "protein-ER insertion by GPI attachment sequence" EXACT [] +is_a: GO:0045048 ! protein insertion into ER membrane + +[Term] +id: GO:0045053 +name: protein retention in Golgi apparatus +namespace: biological_process +def: "The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known." [ISBN:0716731363] +synonym: "maintenance of protein location in Golgi apparatus" RELATED [] +synonym: "protein-Golgi retention" EXACT [] +synonym: "retention of protein in Golgi" EXACT [] +is_a: GO:0032507 ! maintenance of protein location in cell +relationship: part_of GO:0034067 ! protein localization to Golgi apparatus + +[Term] +id: GO:0045054 +name: constitutive secretory pathway +namespace: biological_process +def: "A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space." [GOC:mah, ISBN:0716731363] +synonym: "constitutive exocytosis" EXACT [] +is_a: GO:0006887 ! exocytosis + +[Term] +id: GO:0045055 +name: regulated exocytosis +namespace: biological_process +def: "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand." [GOC:mah, ISBN:0716731363] +synonym: "regulated secretory pathway" EXACT [] +is_a: GO:0006887 ! exocytosis + +[Term] +id: GO:0045056 +name: transcytosis +namespace: biological_process +def: "The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side." [ISBN:0716731363] +xref: Wikipedia:Transcytosis +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0045057 +name: cisternal progression +namespace: biological_process +def: "The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna." [ISBN:0716731363] +synonym: "cisternal maturation" EXACT [] +is_a: GO:0006891 ! intra-Golgi vesicle-mediated transport + +[Term] +id: GO:0045058 +name: T cell selection +namespace: biological_process +def: "The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation." [ISBN:0781735149, PMID:12414722] +synonym: "T lymphocyte selection" EXACT [] +synonym: "T-cell selection" EXACT [] +synonym: "T-lymphocyte selection" EXACT [] +xref: Wikipedia:Thymocyte +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045059 +name: positive thymic T cell selection +namespace: biological_process +def: "The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death." [ISBN:0781735149, PMID:12414722] +synonym: "positive thymic T lymphocyte selection" EXACT [] +synonym: "positive thymic T-cell selection" EXACT [] +synonym: "positive thymic T-lymphocyte selection" EXACT [] +is_a: GO:0043368 ! positive T cell selection +is_a: GO:0045061 ! thymic T cell selection + +[Term] +id: GO:0045060 +name: negative thymic T cell selection +namespace: biological_process +def: "The process of elimination of immature T cells in the thymus which react strongly with self-antigens." [ISBN:0781735149, PMID:12414722] +synonym: "negative thymic T lymphocyte selection" EXACT [] +synonym: "negative thymic T-cell selection" EXACT [] +synonym: "negative thymic T-lymphocyte selection" EXACT [] +is_a: GO:0043383 ! negative T cell selection +is_a: GO:0045061 ! thymic T cell selection + +[Term] +id: GO:0045061 +name: thymic T cell selection +namespace: biological_process +def: "The process of T cell selection that occurs in the thymus." [ISBN:0781735149, PMID:12414722] +synonym: "thymic T lymphocyte selection" EXACT [] +synonym: "thymic T-cell selection" EXACT [] +synonym: "thymic T-lymphocyte selection" EXACT [] +is_a: GO:0045058 ! T cell selection +relationship: part_of GO:0033077 ! T cell differentiation in thymus + +[Term] +id: GO:0045062 +name: extrathymic T cell selection +namespace: biological_process +def: "The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus." [ISBN:0781735149, PMID:7880383] +synonym: "extrathymic T lymphocyte selection" EXACT [] +synonym: "extrathymic T-cell selection" EXACT [] +synonym: "extrathymic T-lymphocyte selection" EXACT [] +is_a: GO:0045058 ! T cell selection +relationship: part_of GO:0033078 ! extrathymic T cell differentiation + +[Term] +id: GO:0045063 +name: T-helper 1 cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:ebc] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T-helper 1 cell development" RELATED [GOC:add] +is_a: GO:0042093 ! T-helper cell differentiation +relationship: part_of GO:0042088 ! T-helper 1 type immune response + +[Term] +id: GO:0045064 +name: T-helper 2 cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4." [CL:0000546, GOC:ebc] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T-helper 2 cell development" RELATED [GOC:add] +is_a: GO:0042093 ! T-helper cell differentiation +relationship: part_of GO:0042092 ! type 2 immune response + +[Term] +id: GO:0045065 +name: cytotoxic T cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell." [GOC:ai] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "cytotoxic T cell development" RELATED [GOC:add] +synonym: "cytotoxic T lymphocyte selection" EXACT [] +synonym: "cytotoxic T-cell selection" EXACT [] +synonym: "cytotoxic T-lymphocyte selection" EXACT [] +is_a: GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045066 +name: regulatory T cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulatory T cell development" RELATED [GOC:add] +synonym: "regulatory T lymphocyte differentiation" EXACT [] +synonym: "regulatory T-cell differentiation" EXACT [] +synonym: "regulatory T-lymphocyte differentiation" EXACT [] +synonym: "suppressor T cell differentiation" EXACT [] +synonym: "suppressor T lymphocyte differentiation" EXACT [] +synonym: "suppressor T-cell differentiation" EXACT [] +synonym: "suppressor T-lymphocyte differentiation" EXACT [] +is_a: GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045067 +name: positive extrathymic T cell selection +namespace: biological_process +def: "The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death." [ISBN:0781735149, PMID:7880383] +synonym: "positive extrathymic T cell selection" RELATED [GOC:add] +synonym: "positive extrathymic T lymphocyte selection" EXACT [] +synonym: "positive extrathymic T-cell selection" EXACT [] +synonym: "positive extrathymic T-lymphocyte selection" EXACT [] +is_a: GO:0043368 ! positive T cell selection +is_a: GO:0045062 ! extrathymic T cell selection + +[Term] +id: GO:0045068 +name: negative extrathymic T cell selection +namespace: biological_process +def: "The process of elimination of extrathymically maturing T cells which react strongly with self-antigens." [ISBN:0781735149, PMID:7880383] +synonym: "negative extrathymic T lymphocyte selection" EXACT [] +synonym: "negative extrathymic T-cell selection" EXACT [] +synonym: "negative extrathymic T-lymphocyte selection" EXACT [] +is_a: GO:0043383 ! negative T cell selection +is_a: GO:0045062 ! extrathymic T cell selection + +[Term] +id: GO:0045069 +name: regulation of viral genome replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral genome replication." [GOC:ai] +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019079 ! viral genome replication +relationship: regulates GO:0019079 ! viral genome replication + +[Term] +id: GO:0045070 +name: positive regulation of viral genome replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral genome replication." [GOC:ai] +synonym: "activation of viral genome replication" NARROW [] +synonym: "stimulation of viral genome replication" NARROW [] +synonym: "up regulation of viral genome replication" EXACT [] +synonym: "up-regulation of viral genome replication" EXACT [] +synonym: "upregulation of viral genome replication" EXACT [] +is_a: GO:0045069 ! regulation of viral genome replication +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019079 ! viral genome replication +relationship: positively_regulates GO:0019079 ! viral genome replication + +[Term] +id: GO:0045071 +name: negative regulation of viral genome replication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication." [GOC:go_curators] +synonym: "down regulation of viral genome replication" EXACT [] +synonym: "down-regulation of viral genome replication" EXACT [] +synonym: "downregulation of viral genome replication" EXACT [] +synonym: "inhibition of viral genome replication" NARROW [] +is_a: GO:0045069 ! regulation of viral genome replication +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019079 ! viral genome replication +relationship: negatively_regulates GO:0019079 ! viral genome replication + +[Term] +id: GO:0045072 +name: regulation of interferon-gamma biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] +synonym: "regulation of interferon-gamma anabolism" EXACT [] +synonym: "regulation of interferon-gamma biosynthesis" EXACT [] +synonym: "regulation of interferon-gamma formation" EXACT [] +synonym: "regulation of interferon-gamma synthesis" EXACT [] +is_a: GO:0032649 ! regulation of interferon-gamma production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042095 ! interferon-gamma biosynthetic process +relationship: regulates GO:0042095 ! interferon-gamma biosynthetic process + +[Term] +id: GO:0045073 +name: regulation of chemokine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] +synonym: "regulation of chemokine anabolism" EXACT [] +synonym: "regulation of chemokine biosynthesis" EXACT [] +synonym: "regulation of chemokine formation" EXACT [] +synonym: "regulation of chemokine synthesis" EXACT [] +is_a: GO:0032642 ! regulation of chemokine production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042033 ! chemokine biosynthetic process +relationship: regulates GO:0042033 ! chemokine biosynthetic process + +[Term] +id: GO:0045074 +name: regulation of interleukin-10 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] +synonym: "regulation of IL-10 biosynthesis" EXACT [] +synonym: "regulation of IL-10 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-10 anabolism" EXACT [] +synonym: "regulation of interleukin-10 biosynthesis" EXACT [] +synonym: "regulation of interleukin-10 formation" EXACT [] +synonym: "regulation of interleukin-10 synthesis" EXACT [] +is_a: GO:0032653 ! regulation of interleukin-10 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042091 ! interleukin-10 biosynthetic process +relationship: regulates GO:0042091 ! interleukin-10 biosynthetic process + +[Term] +id: GO:0045075 +name: regulation of interleukin-12 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] +synonym: "regulation of IL-12 biosynthesis" EXACT [] +synonym: "regulation of IL-12 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-12 anabolism" EXACT [] +synonym: "regulation of interleukin-12 biosynthesis" EXACT [] +synonym: "regulation of interleukin-12 formation" EXACT [] +synonym: "regulation of interleukin-12 synthesis" EXACT [] +is_a: GO:0032655 ! regulation of interleukin-12 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042090 ! interleukin-12 biosynthetic process +relationship: regulates GO:0042090 ! interleukin-12 biosynthetic process + +[Term] +id: GO:0045076 +name: regulation of interleukin-2 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] +synonym: "regulation of IL-2 biosynthesis" EXACT [] +synonym: "regulation of IL-2 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-2 anabolism" EXACT [] +synonym: "regulation of interleukin-2 biosynthesis" EXACT [] +synonym: "regulation of interleukin-2 formation" EXACT [] +synonym: "regulation of interleukin-2 synthesis" EXACT [] +is_a: GO:0032663 ! regulation of interleukin-2 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042094 ! interleukin-2 biosynthetic process +relationship: regulates GO:0042094 ! interleukin-2 biosynthetic process + +[Term] +id: GO:0045077 +name: negative regulation of interferon-gamma biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] +synonym: "down regulation of interferon-gamma biosynthetic process" EXACT [] +synonym: "down-regulation of interferon-gamma biosynthetic process" EXACT [] +synonym: "downregulation of interferon-gamma biosynthetic process" EXACT [] +synonym: "inhibition of interferon-gamma biosynthetic process" NARROW [] +synonym: "negative regulation of interferon-gamma anabolism" EXACT [] +synonym: "negative regulation of interferon-gamma biosynthesis" EXACT [] +synonym: "negative regulation of interferon-gamma formation" EXACT [] +synonym: "negative regulation of interferon-gamma synthesis" EXACT [] +is_a: GO:0032689 ! negative regulation of interferon-gamma production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045072 ! regulation of interferon-gamma biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042095 ! interferon-gamma biosynthetic process +relationship: negatively_regulates GO:0042095 ! interferon-gamma biosynthetic process + +[Term] +id: GO:0045078 +name: positive regulation of interferon-gamma biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] +synonym: "activation of interferon-gamma biosynthetic process" NARROW [] +synonym: "positive regulation of interferon-gamma anabolism" EXACT [] +synonym: "positive regulation of interferon-gamma biosynthesis" EXACT [] +synonym: "positive regulation of interferon-gamma formation" EXACT [] +synonym: "positive regulation of interferon-gamma synthesis" EXACT [] +synonym: "stimulation of interferon-gamma biosynthetic process" NARROW [] +synonym: "up regulation of interferon-gamma biosynthetic process" EXACT [] +synonym: "up-regulation of interferon-gamma biosynthetic process" EXACT [] +synonym: "upregulation of interferon-gamma biosynthetic process" EXACT [] +is_a: GO:0032729 ! positive regulation of interferon-gamma production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045072 ! regulation of interferon-gamma biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042095 ! interferon-gamma biosynthetic process +relationship: positively_regulates GO:0042095 ! interferon-gamma biosynthetic process + +[Term] +id: GO:0045079 +name: negative regulation of chemokine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] +synonym: "down regulation of chemokine biosynthetic process" EXACT [] +synonym: "down-regulation of chemokine biosynthetic process" EXACT [] +synonym: "downregulation of chemokine biosynthetic process" EXACT [] +synonym: "inhibition of chemokine biosynthetic process" NARROW [] +synonym: "negative regulation of chemokine anabolism" EXACT [] +synonym: "negative regulation of chemokine biosynthesis" EXACT [] +synonym: "negative regulation of chemokine formation" EXACT [] +synonym: "negative regulation of chemokine synthesis" EXACT [] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045073 ! regulation of chemokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042033 ! chemokine biosynthetic process +relationship: negatively_regulates GO:0042033 ! chemokine biosynthetic process + +[Term] +id: GO:0045080 +name: positive regulation of chemokine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] +synonym: "activation of chemokine biosynthetic process" NARROW [] +synonym: "positive regulation of chemokine anabolism" EXACT [] +synonym: "positive regulation of chemokine biosynthesis" EXACT [] +synonym: "positive regulation of chemokine formation" EXACT [] +synonym: "positive regulation of chemokine synthesis" EXACT [] +synonym: "stimulation of chemokine biosynthetic process" NARROW [] +synonym: "up regulation of chemokine biosynthetic process" EXACT [] +synonym: "up-regulation of chemokine biosynthetic process" EXACT [] +synonym: "upregulation of chemokine biosynthetic process" EXACT [] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045073 ! regulation of chemokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042033 ! chemokine biosynthetic process +relationship: positively_regulates GO:0042033 ! chemokine biosynthetic process + +[Term] +id: GO:0045081 +name: negative regulation of interleukin-10 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] +synonym: "down regulation of interleukin-10 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-10 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-10 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-10 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-10 biosynthesis" EXACT [] +synonym: "negative regulation of IL-10 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-10 anabolism" EXACT [] +synonym: "negative regulation of interleukin-10 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-10 formation" EXACT [] +synonym: "negative regulation of interleukin-10 synthesis" EXACT [] +is_a: GO:0032693 ! negative regulation of interleukin-10 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045074 ! regulation of interleukin-10 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042091 ! interleukin-10 biosynthetic process +relationship: negatively_regulates GO:0042091 ! interleukin-10 biosynthetic process + +[Term] +id: GO:0045082 +name: positive regulation of interleukin-10 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] +synonym: "activation of interleukin-10 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-10 biosynthesis" EXACT [] +synonym: "positive regulation of IL-10 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-10 anabolism" EXACT [] +synonym: "positive regulation of interleukin-10 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-10 formation" EXACT [] +synonym: "positive regulation of interleukin-10 synthesis" EXACT [] +synonym: "stimulation of interleukin-10 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-10 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-10 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-10 biosynthetic process" EXACT [] +is_a: GO:0032733 ! positive regulation of interleukin-10 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045074 ! regulation of interleukin-10 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042091 ! interleukin-10 biosynthetic process +relationship: positively_regulates GO:0042091 ! interleukin-10 biosynthetic process + +[Term] +id: GO:0045083 +name: negative regulation of interleukin-12 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] +synonym: "down regulation of interleukin-12 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-12 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-12 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-12 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-12 biosynthesis" EXACT [] +synonym: "negative regulation of IL-12 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-12 anabolism" EXACT [] +synonym: "negative regulation of interleukin-12 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-12 formation" EXACT [] +synonym: "negative regulation of interleukin-12 synthesis" EXACT [] +is_a: GO:0032695 ! negative regulation of interleukin-12 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045075 ! regulation of interleukin-12 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042090 ! interleukin-12 biosynthetic process +relationship: negatively_regulates GO:0042090 ! interleukin-12 biosynthetic process + +[Term] +id: GO:0045084 +name: positive regulation of interleukin-12 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] +synonym: "activation of interleukin-12 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-12 biosynthesis" EXACT [] +synonym: "positive regulation of IL-12 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-12 anabolism" EXACT [] +synonym: "positive regulation of interleukin-12 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-12 formation" EXACT [] +synonym: "positive regulation of interleukin-12 synthesis" EXACT [] +synonym: "stimulation of interleukin-12 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-12 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-12 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-12 biosynthetic process" EXACT [] +is_a: GO:0032735 ! positive regulation of interleukin-12 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045075 ! regulation of interleukin-12 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042090 ! interleukin-12 biosynthetic process +relationship: positively_regulates GO:0042090 ! interleukin-12 biosynthetic process + +[Term] +id: GO:0045085 +name: negative regulation of interleukin-2 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] +synonym: "down regulation of interleukin-2 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-2 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-2 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-2 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-2 biosynthesis" EXACT [] +synonym: "negative regulation of IL-2 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-2 anabolism" EXACT [] +synonym: "negative regulation of interleukin-2 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-2 formation" EXACT [] +synonym: "negative regulation of interleukin-2 synthesis" EXACT [] +is_a: GO:0032703 ! negative regulation of interleukin-2 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045076 ! regulation of interleukin-2 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042094 ! interleukin-2 biosynthetic process +relationship: negatively_regulates GO:0042094 ! interleukin-2 biosynthetic process + +[Term] +id: GO:0045086 +name: positive regulation of interleukin-2 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] +synonym: "activation of interleukin-2 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-2 biosynthesis" EXACT [] +synonym: "positive regulation of IL-2 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-2 anabolism" EXACT [] +synonym: "positive regulation of interleukin-2 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-2 formation" EXACT [] +synonym: "positive regulation of interleukin-2 synthesis" EXACT [] +synonym: "stimulation of interleukin-2 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-2 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-2 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-2 biosynthetic process" EXACT [] +is_a: GO:0032743 ! positive regulation of interleukin-2 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045076 ! regulation of interleukin-2 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042094 ! interleukin-2 biosynthetic process +relationship: positively_regulates GO:0042094 ! interleukin-2 biosynthetic process + +[Term] +id: GO:0045087 +name: innate immune response +namespace: biological_process +alt_id: GO:0002226 +def: "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] +synonym: "innate immunity" EXACT [GOC:pg] +synonym: "nonspecific immune response" EXACT [] +xref: Wikipedia:Innate_immune_system +is_a: GO:0006955 ! immune response +is_a: GO:0098542 ! defense response to other organism +property_value: RO:0002161 NCBITaxon_Union:0000023 + +[Term] +id: GO:0045088 +name: regulation of innate immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." [GOC:ebc] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045087 ! innate immune response +relationship: regulates GO:0045087 ! innate immune response + +[Term] +id: GO:0045089 +name: positive regulation of innate immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." [GOC:ebc] +synonym: "stimulation of innate immune response" NARROW [] +synonym: "up regulation of innate immune response" EXACT [] +synonym: "up-regulation of innate immune response" EXACT [] +synonym: "upregulation of innate immune response" EXACT [] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045087 ! innate immune response +relationship: positively_regulates GO:0045087 ! innate immune response + +[Term] +id: GO:0045091 +name: regulation of single stranded viral RNA replication via double stranded DNA intermediate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate." [GOC:go_curators] +synonym: "regulation of retroviral genome replication" EXACT [GOC:bf, GOC:jl] +is_a: GO:0045069 ! regulation of viral genome replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate +relationship: regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate + +[Term] +id: GO:0045092 +name: interleukin-18 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-18; comprises an alpha and a beta subunit." [GOC:mah, PMID:12759435] +synonym: "IL-18 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0045093 +name: obsolete interleukin-18 alpha subunit binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells." [PMID:10653850] +comment: This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits +synonym: "IL-18Ra binding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045094 +name: obsolete interleukin-18 beta subunit binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a." [PMID:10653850] +comment: This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits. +synonym: "IL-18Rb binding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045095 +name: keratin filament +namespace: cellular_component +def: "A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins." [ISBN:0716731363] +synonym: "acidic keratin" RELATED [] +synonym: "basic/neutral keratin" RELATED [] +is_a: GO:0005882 ! intermediate filament + +[Term] +id: GO:0045096 +name: obsolete acidic keratin +namespace: cellular_component +def: "OBSOLETE. A type of intermediate filament." [ISBN:0716731363, ISBN:0815316194] +comment: This term was made obsolete because it represents a gene product. +synonym: "acidic keratin" EXACT [] +synonym: "type I intermediate filament" EXACT [] +is_obsolete: true +replaced_by: GO:0045095 + +[Term] +id: GO:0045097 +name: obsolete basic/neutral keratin +namespace: cellular_component +def: "OBSOLETE. A type of intermediate filament." [ISBN:0716731363, ISBN:0815316194] +comment: This term was made obsolete because it represents a gene product. +synonym: "basic/neutral keratin" EXACT [] +synonym: "type II intermediate filament" EXACT [] +is_obsolete: true +replaced_by: GO:0045095 + +[Term] +id: GO:0045098 +name: type III intermediate filament +namespace: cellular_component +def: "A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments." [ISBN:0716731363] +synonym: "desmin" NARROW [] +synonym: "glial fibrillary acidic protein" NARROW [] +synonym: "peripherin" NARROW [] +synonym: "type III intermediate filament associated protein" NARROW [] +synonym: "vimentin" NARROW [] +is_a: GO:0005882 ! intermediate filament + +[Term] +id: GO:0045099 +name: obsolete vimentin +namespace: cellular_component +def: "OBSOLETE. A type of intermediate filament." [ISBN:0716731363] +comment: This term was made obsolete because it represents a gene product. +synonym: "vimentin" EXACT [] +is_obsolete: true +replaced_by: GO:0045098 + +[Term] +id: GO:0045100 +name: obsolete desmin +namespace: cellular_component +def: "OBSOLETE. A type of intermediate filament." [ISBN:0815316194] +comment: This term was made obsolete because it represents a gene product. +synonym: "desmin" EXACT [] +is_obsolete: true +consider: GO:0045098 + +[Term] +id: GO:0045101 +name: obsolete glial fibrillary acidic protein +namespace: cellular_component +def: "OBSOLETE. Glial fibrillary acidic protein forms filaments in the glial cells that surround neurons and in astrocytes." [ISBN:0716731363] +comment: This term was made obsolete because it represents a gene product. +synonym: "GFAP" EXACT [] +synonym: "glial fibrillary acidic protein" EXACT [] +is_obsolete: true +consider: GO:0045098 + +[Term] +id: GO:0045102 +name: obsolete peripherin +namespace: cellular_component +def: "OBSOLETE. Peripherin is a type III intermediate filament protein found in neurons of the peripheral nervous system." [ISBN:0716731363] +comment: This term was made obsolete because it represents a gene product. +synonym: "peripherin" EXACT [] +is_obsolete: true +consider: GO:0045098 + +[Term] +id: GO:0045103 +name: intermediate filament-based process +namespace: biological_process +def: "Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins." [GOC:ai] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0045104 +name: intermediate filament cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins." [GOC:ai] +synonym: "intermediate filament cytoskeleton organisation" EXACT [] +synonym: "intermediate filament cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007010 ! cytoskeleton organization +is_a: GO:0045103 ! intermediate filament-based process + +[Term] +id: GO:0045105 +name: intermediate filament polymerization or depolymerization +namespace: biological_process +def: "Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament." [GOC:ai] +is_a: GO:0043933 ! protein-containing complex subunit organization +relationship: part_of GO:0045104 ! intermediate filament cytoskeleton organization + +[Term] +id: GO:0045106 +name: intermediate filament depolymerization +namespace: biological_process +def: "Disassembly of intermediate filaments by the removal of component monomers from a filament." [GOC:mah, ISBN:0716731363] +is_a: GO:0045105 ! intermediate filament polymerization or depolymerization +is_a: GO:0051261 ! protein depolymerization + +[Term] +id: GO:0045107 +name: intermediate filament polymerization +namespace: biological_process +def: "Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain." [GOC:mah, PMID:8776884] +is_a: GO:0045105 ! intermediate filament polymerization or depolymerization +is_a: GO:0051258 ! protein polymerization + +[Term] +id: GO:0045108 +name: regulation of intermediate filament polymerization or depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases." [ISBN:0716731363] +is_a: GO:0051493 ! regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045105 ! intermediate filament polymerization or depolymerization +relationship: regulates GO:0045105 ! intermediate filament polymerization or depolymerization + +[Term] +id: GO:0045109 +name: intermediate filament organization +namespace: biological_process +def: "Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:ai] +synonym: "intermediate filament organisation" EXACT [] +is_a: GO:0045104 ! intermediate filament cytoskeleton organization +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0045110 +name: intermediate filament bundle assembly +namespace: biological_process +def: "The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs." [ISBN:0716731363] +synonym: "tonofilament assembly" NARROW [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0045109 ! intermediate filament organization + +[Term] +id: GO:0045111 +name: intermediate filament cytoskeleton +namespace: cellular_component +def: "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell." [ISBN:0716731363] +is_a: GO:0005856 ! cytoskeleton + +[Term] +id: GO:0045112 +name: integrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules." [GOC:go_curators, ISBN:0198506732] +synonym: "integrin anabolism" EXACT [] +synonym: "integrin biosynthesis" EXACT [] +synonym: "integrin formation" EXACT [] +synonym: "integrin synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +relationship: part_of GO:0007009 ! plasma membrane organization + +[Term] +id: GO:0045113 +name: regulation of integrin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] +synonym: "regulation of integrin anabolism" EXACT [] +synonym: "regulation of integrin biosynthesis" EXACT [] +synonym: "regulation of integrin formation" EXACT [] +synonym: "regulation of integrin synthesis" EXACT [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045112 ! integrin biosynthetic process +relationship: regulates GO:0045112 ! integrin biosynthetic process + +[Term] +id: GO:0045114 +name: beta 2 integrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit." [GOC:go_curators] +synonym: "beta 2 integrin anabolism" EXACT [] +synonym: "beta 2 integrin biosynthesis" EXACT [] +synonym: "beta 2 integrin formation" EXACT [] +synonym: "beta 2 integrin synthesis" EXACT [] +is_a: GO:0045112 ! integrin biosynthetic process + +[Term] +id: GO:0045115 +name: regulation of beta 2 integrin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] +synonym: "regulation of beta 2 integrin anabolism" EXACT [] +synonym: "regulation of beta 2 integrin biosynthesis" EXACT [] +synonym: "regulation of beta 2 integrin formation" EXACT [] +synonym: "regulation of beta 2 integrin synthesis" EXACT [] +is_a: GO:0045113 ! regulation of integrin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045114 ! beta 2 integrin biosynthetic process +relationship: regulates GO:0045114 ! beta 2 integrin biosynthetic process + +[Term] +id: GO:0045116 +name: protein neddylation +namespace: biological_process +alt_id: GO:0019943 +def: "Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein." [PMID:11698580] +comment: Note that currently, the only known substrates of neddylation are cullin family proteins. +synonym: "RUB1-protein conjugation" EXACT [] +is_a: GO:0032446 ! protein modification by small protein conjugation + +[Term] +id: GO:0045117 +name: azole transmembrane transport +namespace: biological_process +def: "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane." [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole] +synonym: "azole transport" RELATED [] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0045119 +name: azole:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances." [GOC:ai, ISBN:3527307206, Wikipedia:Azole] +synonym: "azole:hydrogen antiporter activity" EXACT [] +synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" NARROW [] +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity + +[Term] +id: GO:0045120 +name: pronucleus +namespace: cellular_component +def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732] +xref: Wikipedia:Pronucleus +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0045121 +name: membrane raft +namespace: cellular_component +def: "Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198, PMID:20044567] +synonym: "GEM domain" RELATED [] +synonym: "glycolipid-enriched membrane domain" RELATED [] +synonym: "lipid raft" EXACT [] +xref: Wikipedia:Lipid_raft +is_a: GO:0098857 ! membrane microdomain + +[Term] +id: GO:0045122 +name: aflatoxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450." [ISBN:0716731363, ISBN:0815316194, PMID:15006741] +synonym: "aflatoxin anabolism" EXACT [] +synonym: "aflatoxin biosynthesis" EXACT [] +synonym: "aflatoxin formation" EXACT [] +synonym: "aflatoxin synthesis" EXACT [] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0046222 ! aflatoxin metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +relationship: has_part GO:0042469 ! versicolorin reductase activity +relationship: has_part GO:0046572 ! versicolorin B synthase activity +relationship: has_part GO:0047145 ! demethylsterigmatocystin 6-O-methyltransferase activity +relationship: has_part GO:0047146 ! sterigmatocystin 7-O-methyltransferase activity +relationship: has_part GO:0102973 ! norsolorinate anthrone synthase activity +relationship: has_part GO:0140393 ! norsolorinic acid ketoreductase activity +relationship: has_part GO:0140395 ! averantin hydroxylase activity +relationship: has_part GO:0140396 ! 5'-hydroxyaverantin dehydrogenase activity +relationship: has_part GO:0140397 ! versiconal hemiacetal acetate esterase activity +relationship: has_part GO:0140398 ! versicolorin B desaturase activity + +[Term] +id: GO:0045123 +name: cellular extravasation +namespace: biological_process +def: "The migration of a leukocyte from the blood vessels into the surrounding tissue." [GOC:jl] +synonym: "immune cell cellular extravasation" EXACT [] +synonym: "leucocyte cellular extravasation" EXACT [] +synonym: "leukocyte cellular extravasation" EXACT [] +synonym: "transendothelial leukocyte migration" EXACT [GOC:rl] +xref: Wikipedia:Leukocyte_extravasation +is_a: GO:0050900 ! leukocyte migration + +[Term] +id: GO:0045124 +name: regulation of bone resorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)." [GOC:ai] +is_a: GO:0046850 ! regulation of bone remodeling +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045453 ! bone resorption +relationship: regulates GO:0045453 ! bone resorption + +[Term] +id: GO:0045125 +name: bioactive lipid receptor activity +namespace: molecular_function +def: "Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes." [GOC:bf, GOC:mah, PMID:12215548, PMID:18216770] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0045127 +name: N-acetylglucosamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+)." [EC:2.7.1.59, RHEA:17417] +synonym: "2-acetylamino-2-deoxy-D-glucose kinase activity" EXACT [EC:2.7.1.59] +synonym: "acetylaminodeoxyglucokinase activity" EXACT [EC:2.7.1.59] +synonym: "acetylglucosamine kinase (phosphorylating)" EXACT [EC:2.7.1.59] +synonym: "ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.59] +synonym: "ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.59] +synonym: "GlcNAc kinase activity" EXACT [EC:2.7.1.59] +xref: EC:2.7.1.59 +xref: KEGG_REACTION:R01201 +xref: MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN +xref: Reactome:R-HSA-6803771 "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P" +xref: RHEA:17417 +is_a: GO:0019200 ! carbohydrate kinase activity + +[Term] +id: GO:0045128 +name: negative regulation of reciprocal meiotic recombination +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate." [GOC:ai, GOC:dph, GOC:tb] +synonym: "down regulation of meiotic recombination" EXACT [] +synonym: "down-regulation of meiotic recombination" EXACT [] +synonym: "downregulation of meiotic recombination" EXACT [] +synonym: "inhibition of meiotic recombination" NARROW [] +synonym: "suppression of meiotic recombination" EXACT [] +is_a: GO:0010520 ! regulation of reciprocal meiotic recombination +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:0110029 ! negative regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007131 ! reciprocal meiotic recombination +relationship: negatively_regulates GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0045129 +name: NAD-independent histone deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone." [EC:3.5.1.17, RHEA:24548] +synonym: "AcuC" RELATED [] +is_a: GO:0004407 ! histone deacetylase activity + +[Term] +id: GO:0045130 +name: keratan sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate." [EC:2.8.2.21] +synonym: "3'-phosphoadenylyl keratan sulfotransferase activity" EXACT [EC:2.8.2.21] +synonym: "3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity" EXACT [EC:2.8.2.21] +synonym: "3'-phosphoadenylylsulfate:keratan sulfotransferase activity" EXACT [EC:2.8.2.21] +synonym: "keratan sulfate Gal-6-sulfotransferase activity" EXACT [] +synonym: "keratan sulfate sulfotransferase activity" EXACT [EC:2.8.2.21] +synonym: "keratan sulphotransferase activity" EXACT [] +xref: EC:2.8.2.21 +xref: MetaCyc:KERATAN-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-2046175 "Further sulfation on galactose residues produces KSPG" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0045131 +name: pre-mRNA branch point binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pre-mRNA branch point sequence, located upstream of the 3' splice site." [PMID:11691992, PMID:9722632] +is_a: GO:0036002 ! pre-mRNA binding + +[Term] +id: GO:0045132 +name: meiotic chromosome segregation +namespace: biological_process +def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah] +is_a: GO:0098813 ! nuclear chromosome segregation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0098813 ! nuclear chromosome segregation +intersection_of: part_of GO:0140013 ! meiotic nuclear division +relationship: part_of GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0045133 +name: 2,3-dihydroxybenzoate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)." [EC:1.13.11.14, RHEA:18477] +synonym: "2,3-dihydroxybenzoate 1,2-dioxygenase activity" EXACT [EC:1.13.11.14] +synonym: "2,3-dihydroxybenzoate oxygenase activity" EXACT [EC:1.13.11.14] +synonym: "2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.14] +synonym: "2,3-dihydroxybenzoic oxygenase activity" EXACT [EC:1.13.11.14] +synonym: "o-pyrocatechuate oxygenase activity" EXACT [EC:1.13.11.14] +xref: EC:1.13.11.14 +xref: KEGG_REACTION:R01507 +xref: MetaCyc:1.13.11.14-RXN +xref: RHEA:18477 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0045134 +name: uridine-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP + H2O = UMP + phosphate." [EC:3.6.1.6] +synonym: "UDP phosphohydrolase activity" EXACT [KEGG_REACTION:R00155] +synonym: "UDPase activity" EXACT [EC:3.6.1.6] +synonym: "uridine 5'-diphosphatase activity" EXACT [EC:3.6.1.6] +synonym: "uridine diphosphatase activity" EXACT [EC:3.6.1.6] +xref: EC:3.6.1.6 +xref: KEGG_REACTION:R00155 +xref: MetaCyc:RXN-12197 +is_a: GO:0017110 ! nucleoside-diphosphatase activity + +[Term] +id: GO:0045135 +name: poly(beta-D-mannuronate) lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends." [EC:4.2.2.3] +synonym: "alginase activity" EXACT [EC:4.2.2.3] +synonym: "alginase I" RELATED [EC:4.2.2.3] +synonym: "alginate lyase activity" EXACT [EC:4.2.2.3] +synonym: "alginate lyase I activity" NARROW [EC:4.2.2.3] +synonym: "poly(beta-D-1,4-mannuronide) lyase activity" EXACT [EC:4.2.2.3] +synonym: "poly(mana) alginate lyase activity" NARROW [EC:4.2.2.3] +xref: EC:4.2.2.3 +xref: MetaCyc:4.2.2.3-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0045136 +name: development of secondary sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion." [GOC:ai] +is_a: GO:0003006 ! developmental process involved in reproduction + +[Term] +id: GO:0045137 +name: development of primary sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0007275 ! multicellular organism development +relationship: part_of GO:0007548 ! sex differentiation + +[Term] +id: GO:0045138 +name: nematode male tail tip morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome." [GOC:kmv, PMID:16806150, PMID:18050419, PMID:21408209, PMID:7409314] +synonym: "male tail morphogenesis" BROAD [] +synonym: "male tail tip morphogenesis" RELATED [GOC:kmv] +synonym: "tail tip morphogenesis" RELATED [GOC:kmv] +is_a: GO:0090598 ! male anatomical structure morphogenesis + +[Term] +id: GO:0045139 +name: obsolete copper sensitivity/resistance +namespace: biological_process +def: "OBSOLETE. (Was not defined before being made obsolete)." [GOC:go_curators] +comment: This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. +synonym: "copper sensitivity/resistance" EXACT [] +is_obsolete: true +replaced_by: GO:0046688 + +[Term] +id: GO:0045140 +name: inositol phosphoceramide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide." [MetaCyc:RXN3O-581, PMID:9405490, PMID:9614099] +synonym: "IPC synthase activity" EXACT [] +xref: MetaCyc:RXN3O-581 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0045141 +name: meiotic telomere clustering +namespace: biological_process +def: "The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis." [GOC:vw, PMID:10690419] +synonym: "bouquet biosynthesis" NARROW [] +synonym: "bouquet formation" NARROW [] +is_a: GO:0034397 ! telomere localization +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +is_a: GO:0090220 ! chromosome localization to nuclear envelope involved in homologous chromosome segregation + +[Term] +id: GO:0045142 +name: triplex DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination." [PMID:10681538] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0045143 +name: homologous chromosome segregation +namespace: biological_process +alt_id: GO:0007061 +def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, ISBN:0815316194] +synonym: "meiosis I, chromosome segregation" EXACT [] +is_a: GO:0045132 ! meiotic chromosome segregation +intersection_of: GO:0098813 ! nuclear chromosome segregation +intersection_of: part_of GO:0007127 ! meiosis I +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0045144 +name: meiotic sister chromatid segregation +namespace: biological_process +def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] +synonym: "meiosis II, chromosome segregation" EXACT [] +is_a: GO:0000819 ! sister chromatid segregation +is_a: GO:0045132 ! meiotic chromosome segregation +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +intersection_of: GO:0000819 ! sister chromatid segregation +intersection_of: part_of GO:0007135 ! meiosis II +relationship: part_of GO:0007135 ! meiosis II + +[Term] +id: GO:0045145 +name: single-stranded DNA 5'-3' exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule." [GOC:ai, GOC:elh, PMID:20086101] +synonym: "single-stranded DNA specific 5'-3' exodeoxyribonuclease activity" RELATED [] +synonym: "ssDNA-specific 5'-3' exodeoxyribonuclease activity" RELATED [GOC:mah] +is_a: GO:0008297 ! single-stranded DNA exodeoxyribonuclease activity +is_a: GO:0035312 ! 5'-3' exodeoxyribonuclease activity + +[Term] +id: GO:0045146 +name: initiation of acetate catabolic process by acetate +namespace: biological_process +def: "The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [PMID:11741859] +synonym: "initiation of acetate breakdown by acetate" EXACT [] +synonym: "initiation of acetate degradation by acetate" EXACT [] +is_a: GO:0043077 ! initiation of acetate catabolic process +relationship: part_of GO:0010034 ! response to acetate + +[Term] +id: GO:0045147 +name: regulation of initiation of acetate catabolic process by acetate +namespace: biological_process +def: "Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] +synonym: "regulation of initiation of acetate breakdown by acetate" EXACT [] +synonym: "regulation of initiation of acetate degradation by acetate" EXACT [] +is_a: GO:0045734 ! regulation of acetate catabolic process +is_a: GO:1901457 ! regulation of response to acetate +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045146 ! initiation of acetate catabolic process by acetate +relationship: regulates GO:0045146 ! initiation of acetate catabolic process by acetate + +[Term] +id: GO:0045148 +name: tripeptide aminopeptidase activity +namespace: molecular_function +def: "Catalysis of the release of the N-terminal residue from a tripeptide." [EC:3.4.11.4] +synonym: "alanine-phenylalanine-proline arylamidase activity" EXACT [EC:3.4.11.4] +synonym: "aminoexotripeptidase activity" EXACT [EC:3.4.11.4] +synonym: "aminotripeptidase activity" EXACT [] +synonym: "imidoendopeptidase activity" EXACT [EC:3.4.11.4] +synonym: "lymphopeptidase activity" EXACT [EC:3.4.11.4] +synonym: "peptidase B" RELATED [EC:3.4.11.4] +synonym: "peptidase T" EXACT [] +xref: EC:3.4.11.4 +xref: MetaCyc:3.4.11.4-RXN +is_a: GO:0004177 ! aminopeptidase activity +is_a: GO:0034701 ! tripeptidase activity + +[Term] +id: GO:0045149 +name: acetoin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source." [GOC:mlg] +synonym: "acetoin metabolism" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process + +[Term] +id: GO:0045150 +name: acetoin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone." [GOC:mlg] +synonym: "acetoin breakdown" EXACT [] +synonym: "acetoin catabolism" EXACT [] +synonym: "acetoin degradation" EXACT [] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0045149 ! acetoin metabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0045151 +name: acetoin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone." [GOC:mlg] +synonym: "acetoin anabolism" EXACT [] +synonym: "acetoin biosynthesis" EXACT [] +synonym: "acetoin formation" EXACT [] +synonym: "acetoin synthesis" EXACT [] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0045149 ! acetoin metabolic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0045152 +name: antisigma factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator." [GOC:mlg] +synonym: "antisigma factor antagonist activity" NARROW [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0045153 +name: electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity +namespace: molecular_function +def: "Enables the directed movement of electrons within the CoQH2-cytochrome c reductase complex." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +synonym: "cytochrome b562" NARROW [] +synonym: "cytochrome b566" NARROW [] +synonym: "cytochrome c1" NARROW [] +synonym: "soluble cytochrome b562" RELATED [] +xref: Reactome:R-HSA-164651 "Electron transfer from ubiquinol to cytochrome c of complex III" +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045154 +name: electron transporter, transferring electrons within cytochrome c oxidase complex activity +namespace: molecular_function +def: "Enables the directed movement of electrons within the cytochrome c oxidase complex." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +synonym: "cytochrome a" NARROW [] +synonym: "cytochrome a3/copper complex" NARROW [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045155 +name: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity +namespace: molecular_function +def: "Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +synonym: "cytochrome c" NARROW [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045156 +name: electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity +namespace: molecular_function +def: "Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +synonym: "cytochrome bc1 complex" NARROW [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045157 +name: electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity +namespace: molecular_function +def: "Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045158 +name: electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity +namespace: molecular_function +def: "Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II." [GOC:ai, ISBN:0716731363] +synonym: "cytochrome" RELATED [] +synonym: "cytochrome b/b6" RELATED [] +synonym: "cytochrome b6" NARROW [] +synonym: "cytochrome f" NARROW [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0045159 +name: myosin II binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] +is_a: GO:0017022 ! myosin binding + +[Term] +id: GO:0045160 +name: myosin I complex +namespace: cellular_component +def: "A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:9438839] +is_a: GO:0016461 ! unconventional myosin complex + +[Term] +id: GO:0045161 +name: neuronal ion channel clustering +namespace: biological_process +def: "The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation." [PMID:11456440] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0042551 ! neuron maturation + +[Term] +id: GO:0045162 +name: clustering of voltage-gated sodium channels +namespace: biological_process +def: "The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization." [PMID:11456440] +synonym: "clustering of voltage gated sodium channels" EXACT [] +synonym: "clustering of voltage-dependent sodium channels" EXACT [] +synonym: "Nav channel clustering" EXACT [] +synonym: "voltage-gated sodium channel clustering" EXACT [] +is_a: GO:0045161 ! neuronal ion channel clustering + +[Term] +id: GO:0045163 +name: clustering of voltage-gated potassium channels +namespace: biological_process +def: "The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode." [PMID:11456440] +synonym: "clustering of voltage gated potassium channels" EXACT [] +synonym: "clustering of voltage-dependent potassium channels" EXACT [] +synonym: "Kv channel clustering" EXACT [] +synonym: "voltage-gated potassium channel clustering" EXACT [] +is_a: GO:0045161 ! neuronal ion channel clustering + +[Term] +id: GO:0045164 +name: obsolete secretin (sensu Mammalia) +namespace: molecular_function +def: "OBSOLETE. Secretin is a hormone that takes part in the digestion process. It also has effects on organs other than gastrointestinal tract." [PMID:11320551] +comment: This term was made obsolete because it represents a gene product rather than a molecular function. +synonym: "secretin (sensu Mammalia)" EXACT [] +is_obsolete: true +consider: GO:0046659 + +[Term] +id: GO:0045165 +name: cell fate commitment +namespace: biological_process +def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [ISBN:0716731185] +comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0030154 ! cell differentiation + +[Term] +id: GO:0045167 +name: asymmetric protein localization involved in cell fate determination +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types." [GOC:ai] +synonym: "asymmetric protein localisation involved in cell fate determination" EXACT [GOC:mah] +synonym: "asymmetric protein localization involved in cell fate commitment" EXACT [] +synonym: "asymmetric protein localization resulting in cell fate commitment" EXACT [] +synonym: "cell fate commitment, asymmetric protein localization" EXACT [] +is_a: GO:0008104 ! protein localization +intersection_of: GO:0008104 ! protein localization +intersection_of: part_of GO:0001709 ! cell fate determination +relationship: part_of GO:0001709 ! cell fate determination + +[Term] +id: GO:0045168 +name: cell-cell signaling involved in cell fate commitment +namespace: biological_process +def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "cell fate commitment, cell-cell signaling" EXACT [] +synonym: "cell fate commitment, cell-cell signalling" EXACT [] +synonym: "cell-cell signaling during in cell fate commitment" EXACT [] +synonym: "cell-cell signaling resulting in cell fate commitment" EXACT [] +synonym: "cell-cell signalling during cell fate commitment" EXACT [] +synonym: "cell-cell signalling involved in cell fate specification" NARROW [GOC:dph, GOC:tb] +synonym: "cell-cell signalling resulting in cell fate commitment" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0045165 ! cell fate commitment +relationship: part_of GO:0045165 ! cell fate commitment + +[Term] +id: GO:0045169 +name: fusome +namespace: cellular_component +def: "A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle." [GOC:bf, PMID:12655376] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045170 +name: spectrosome +namespace: cellular_component +def: "A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome." [GOC:bf] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045171 +name: intercellular bridge +namespace: cellular_component +def: "A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised." [PMID:9635420] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0045172 +name: germline ring canal +namespace: cellular_component +def: "Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells." [GOC:mtg_sensu, PMID:9635420, PMID:9655801] +is_a: GO:0045171 ! intercellular bridge + +[Term] +id: GO:0045173 +name: O-sialoglycoprotein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities." [GOC:go_curators, PMID:8824323] +synonym: "O-sialoglycoprotein breakdown" EXACT [] +synonym: "O-sialoglycoprotein catabolism" EXACT [] +synonym: "O-sialoglycoprotein degradation" EXACT [] +is_a: GO:0006516 ! glycoprotein catabolic process + +[Term] +id: GO:0045174 +name: glutathione dehydrogenase (ascorbate) activity +namespace: molecular_function +def: "Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide." [EC:1.8.5.1, RHEA:24424] +synonym: "dehydroascorbate reductase activity" EXACT [] +synonym: "dehydroascorbic acid reductase activity" EXACT [EC:1.8.5.1] +synonym: "dehydroascorbic reductase activity" EXACT [EC:1.8.5.1] +synonym: "DHA reductase activity" EXACT [EC:1.8.5.1] +synonym: "GDOR" RELATED [EC:1.8.5.1] +synonym: "glutathione dehydroascorbate reductase activity" EXACT [EC:1.8.5.1] +synonym: "glutathione:dehydroascorbate oxidoreductase activity" EXACT [EC:1.8.5.1] +synonym: "glutathione:dehydroascorbic acid oxidoreductase activity" EXACT [EC:1.8.5.1] +xref: EC:1.8.5.1 +xref: KEGG_REACTION:R01108 +xref: MetaCyc:1.8.5.1-RXN +xref: Reactome:R-HSA-198813 "2xGSTOs reduce DHvitC to VitC" +xref: RHEA:24424 +is_a: GO:0015038 ! glutathione disulfide oxidoreductase activity +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0045175 +name: basal protein localization +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained in, basal regions of the cell." [GOC:bf] +synonym: "basal protein localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of basal protein localization" EXACT [] +synonym: "establishment and maintenance of protein localization in basal part of cell" EXACT [] +is_a: GO:0008104 ! protein localization + +[Term] +id: GO:0045176 +name: apical protein localization +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained in, apical regions of the cell." [GOC:bf] +synonym: "apical protein localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of apical protein localization" EXACT [] +synonym: "establishment and maintenance of protein localization in apical part of cell" EXACT [] +is_a: GO:0008104 ! protein localization + +[Term] +id: GO:0045177 +name: apical part of cell +namespace: cellular_component +def: "The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue." [GOC:mah, ISBN:0815316194] +subset: goslim_pir +synonym: "apical region of cell" EXACT [GOC:krc] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0045178 +name: basal part of cell +namespace: cellular_component +def: "The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue." [GOC:mah, ISBN:0815316194] +subset: goslim_pir +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0045179 +name: apical cortex +namespace: cellular_component +def: "The region that lies just beneath the plasma membrane on the apical edge of a cell." [GOC:bf] +is_a: GO:0099738 ! cell cortex region +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0045177 ! apical part of cell +relationship: part_of GO:0045177 ! apical part of cell + +[Term] +id: GO:0045180 +name: basal cortex +namespace: cellular_component +def: "The region that lies just beneath the plasma membrane on the basal edge of a cell." [GOC:bf] +is_a: GO:0099738 ! cell cortex region +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0045178 ! basal part of cell +relationship: part_of GO:0045178 ! basal part of cell + +[Term] +id: GO:0045181 +name: glutamate synthase activity, NAD(P)H as acceptor +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+." [EC:1.4.1.13, EC:1.4.1.14] +synonym: "glutamate synthase activity, NADH or NADPH as acceptor" RELATED [] +is_a: GO:0015930 ! glutamate synthase activity +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0045182 +name: translation regulator activity +namespace: molecular_function +def: "Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome." [GOC:ai] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_drosophila +subset: goslim_pir +subset: goslim_plant +synonym: "translation factor activity" EXACT [] +is_a: GO:0003674 ! molecular_function +intersection_of: GO:0003674 ! molecular_function +intersection_of: part_of GO:0006417 ! regulation of translation +relationship: part_of GO:0006417 ! regulation of translation + +[Term] +id: GO:0045183 +name: translation factor activity, non-nucleic acid binding +namespace: molecular_function +def: "A translation regulator activity that does not involve binding to nucleic acids." [GOC:ai, GOC:dph, GOC:tb] +is_a: GO:0045182 ! translation regulator activity + +[Term] +id: GO:0045184 +name: establishment of protein localization +namespace: biological_process +def: "The directed movement of a protein to a specific location." [GOC:bf] +synonym: "establishment of protein localisation" EXACT [GOC:mah] +synonym: "protein positioning" EXACT [] +synonym: "protein recruitment" EXACT [] +is_a: GO:0008104 ! protein localization +is_a: GO:0051234 ! establishment of localization + +[Term] +id: GO:0045185 +name: maintenance of protein location +namespace: biological_process +def: "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." [GOC:bf] +synonym: "active protein retrieval" NARROW [] +synonym: "maintenance of protein localization" RELATED [GOC:dph, GOC:tb] +synonym: "protein retention" NARROW [] +synonym: "protein sequestering" NARROW [] +is_a: GO:0051235 ! maintenance of location +relationship: part_of GO:0008104 ! protein localization + +[Term] +id: GO:0045186 +name: zonula adherens assembly +namespace: biological_process +def: "Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells." [GOC:bf] +is_a: GO:0034333 ! adherens junction assembly +relationship: part_of GO:0043297 ! apical junction assembly + +[Term] +id: GO:0045187 +name: regulation of circadian sleep/wake cycle, sleep +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals." [GOC:jl, ISBN:0192800981] +synonym: "regulation of sleep" EXACT [] +is_a: GO:0042749 ! regulation of circadian sleep/wake cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050802 ! circadian sleep/wake cycle, sleep +relationship: regulates GO:0050802 ! circadian sleep/wake cycle, sleep + +[Term] +id: GO:0045188 +name: regulation of circadian sleep/wake cycle, non-REM sleep +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep." [GOC:go_curators] +synonym: "regulation of non-REM sleep" EXACT [] +is_a: GO:0045187 ! regulation of circadian sleep/wake cycle, sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep +relationship: regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep + +[Term] +id: GO:0045189 +name: connective tissue growth factor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta." [http://www.copewithcytokines.de] +synonym: "connective tissue growth factor anabolism" EXACT [] +synonym: "connective tissue growth factor biosynthesis" EXACT [] +synonym: "connective tissue growth factor formation" EXACT [] +synonym: "connective tissue growth factor synthesis" EXACT [] +synonym: "CTGF biosynthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032601 ! connective tissue growth factor production + +[Term] +id: GO:0045190 +name: isotype switching +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus." [ISBN:0781735149] +comment: Note that IgM and IgD can be coexpressed by B cells via an alternate splicing mechanism, but true recombinational isotype switching to IgD has been demonstrated as well. Note that this term is best used to annotate gene products which are involved in the mechanism of DNA recombination used in isotype switching, like the B cell specific Swap70 factor in the mouse, rather than gene products which promote isotype switching such as cytokines or co-stimulatory molecules, which should instead be annotated to 'regulation of isotype switching ; GO:0045191'. +synonym: "class switch recombination" EXACT [] +synonym: "class switching" EXACT [] +synonym: "isotype switch recombination" EXACT [] +xref: Wikipedia:Immunoglobulin_class_switching +is_a: GO:0002204 ! somatic recombination of immunoglobulin genes involved in immune response +is_a: GO:0002312 ! B cell activation involved in immune response + +[Term] +id: GO:0045191 +name: regulation of isotype switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isotype switching." [GOC:ai] +synonym: "regulation of class switch recombination" EXACT [] +synonym: "regulation of class switching" EXACT [] +synonym: "regulation of isotype switch recombination" EXACT [] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +is_a: GO:0050864 ! regulation of B cell activation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045190 ! isotype switching +relationship: regulates GO:0045190 ! isotype switching + +[Term] +id: GO:0045192 +name: obsolete low-density lipoprotein catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats." [GOC:go_curators, ISBN:0198506732] +comment: This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds. +synonym: "LDL catabolic process" EXACT [] +synonym: "LDL catabolism" EXACT [] +synonym: "low-density lipoprotein breakdown" EXACT [] +synonym: "low-density lipoprotein catabolic process" EXACT [] +synonym: "low-density lipoprotein catabolism" EXACT [] +synonym: "low-density lipoprotein degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045193 +name: obsolete acetylated low-density lipoprotein catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins." [GOC:go_curators] +comment: This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds. +synonym: "Ac-LDL catabolic process" EXACT [] +synonym: "Ac-LDL catabolism" EXACT [] +synonym: "acetylated low-density lipoprotein breakdown" EXACT [] +synonym: "acetylated low-density lipoprotein catabolic process" EXACT [] +synonym: "acetylated low-density lipoprotein catabolism" EXACT [] +synonym: "acetylated low-density lipoprotein degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045194 +name: obsolete oxidized low-density lipoprotein catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins." [GOC:go_curators] +comment: This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds. +synonym: "Ox-LDL catabolic process" EXACT [] +synonym: "Ox-LDL catabolism" EXACT [] +synonym: "oxidized low-density lipoprotein breakdown" EXACT [] +synonym: "oxidized low-density lipoprotein catabolic process" EXACT [] +synonym: "oxidized low-density lipoprotein catabolism" EXACT [] +synonym: "oxidized low-density lipoprotein degradation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045195 +name: obsolete gallstone formation +namespace: biological_process +def: "OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile." [http://www.ddc.musc.edu/ddc_pro/pro_development/basic_science/gallstones.htm] +comment: This term was made obsolete because the process it represents is pathological. +synonym: "gallstone formation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045196 +name: establishment or maintenance of neuroblast polarity +namespace: biological_process +alt_id: GO:0043339 +alt_id: GO:0043342 +def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083] +synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT [] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +relationship: part_of GO:0055059 ! asymmetric neuroblast division + +[Term] +id: GO:0045197 +name: establishment or maintenance of epithelial cell apical/basal polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell." [GOC:bf, GOC:mah] +is_a: GO:0035088 ! establishment or maintenance of apical/basal cell polarity + +[Term] +id: GO:0045198 +name: establishment of epithelial cell apical/basal polarity +namespace: biological_process +def: "The specification and formation of the apicobasal polarity of an epithelial cell." [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb] +is_a: GO:0030859 ! polarized epithelial cell differentiation +is_a: GO:0035089 ! establishment of apical/basal cell polarity +is_a: GO:0045197 ! establishment or maintenance of epithelial cell apical/basal polarity +is_a: GO:0090162 ! establishment of epithelial cell polarity + +[Term] +id: GO:0045199 +name: maintenance of epithelial cell apical/basal polarity +namespace: biological_process +def: "The maintenance of the apicobasal polarity of an epithelial cell." [GOC:bf] +is_a: GO:0035090 ! maintenance of apical/basal cell polarity +is_a: GO:0045197 ! establishment or maintenance of epithelial cell apical/basal polarity + +[Term] +id: GO:0045200 +name: establishment of neuroblast polarity +namespace: biological_process +alt_id: GO:0043340 +alt_id: GO:0043343 +def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] +synonym: "establishment of neuroblast cell polarity" EXACT [] +is_a: GO:0030010 ! establishment of cell polarity +is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity + +[Term] +id: GO:0045201 +name: maintenance of neuroblast polarity +namespace: biological_process +alt_id: GO:0043341 +alt_id: GO:0043344 +def: "The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] +synonym: "maintenance of neuroblast cell polarity" EXACT [] +is_a: GO:0030011 ! maintenance of cell polarity +is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity + +[Term] +id: GO:0045202 +name: synapse +namespace: cellular_component +def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] +subset: goslim_agr +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pir +subset: goslim_synapse +synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124] +synonym: "mixed synapse" NARROW [NIF_Subcellular:sao1506103497] +synonym: "synaptic junction" EXACT [] +xref: NIF_Subcellular:sao914572699 +xref: Wikipedia:Chemical_synapse +is_a: GO:0030054 ! cell junction + +[Term] +id: GO:0045203 +name: integral component of cell outer membrane +namespace: cellular_component +def: "The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators, GOC:mtg_sensu] +synonym: "integral to cell outer membrane" NARROW [] +synonym: "integral to external membrane" RELATED [] +synonym: "integral to outer membrane" RELATED [] +is_a: GO:0016021 ! integral component of membrane +is_a: GO:0031230 ! intrinsic component of cell outer membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009279 ! cell outer membrane + +[Term] +id: GO:0045204 +name: MAPK export from nucleus +namespace: biological_process +def: "The directed movement of a MAP kinase from the nucleus to the cytoplasm." [GOC:ebc] +synonym: "cytoplasmic translocation of MAP kinase" EXACT [] +synonym: "cytoplasmic translocation of mitogen-activated protein kinase" EXACT [] +synonym: "MAPK export from cell nucleus" EXACT [] +synonym: "MAPK export out of nucleus" EXACT [] +synonym: "MAPK transport from nucleus to cytoplasm" EXACT [] +synonym: "MAPK-nucleus export" EXACT [] +is_a: GO:0006611 ! protein export from nucleus + +[Term] +id: GO:0045205 +name: obsolete MAPK transporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the directed movement of MAP kinase into, out of or within a cell, or between cells." [GOC:ebc, GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because we do not know what it was intended to represent when it was created. +synonym: "MAPK transporter activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045206 +name: obsolete MAPK phosphatase transporter activity +namespace: molecular_function +alt_id: GO:0045207 +def: "OBSOLETE. Enables the directed movement of MAPK phosphatase into, out of or within a cell, or between cells." [GOC:ebc, GOC:mtg_transport, ISBN:0815340729] +comment: This term was made obsolete because we do not know what it was intended to represent when it was created. +synonym: "leptomycin B-sensitive MAPK phosphatase transporter activity" NARROW [] +synonym: "leptomycin B-sensitive MKP shuttle" NARROW [] +synonym: "MAPK phosphatase transporter activity" EXACT [] +synonym: "MKP shuttle" NARROW [] +is_obsolete: true + +[Term] +id: GO:0045208 +name: MAPK phosphatase export from nucleus +namespace: biological_process +def: "The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm." [GOC:ebc] +synonym: "MAPK phosphatase export from cell nucleus" EXACT [] +synonym: "MAPK phosphatase export out of nucleus" EXACT [] +synonym: "MAPK phosphatase transport from nucleus to cytoplasm" EXACT [] +synonym: "MAPK phosphatase-nucleus export" EXACT [] +is_a: GO:0006611 ! protein export from nucleus + +[Term] +id: GO:0045209 +name: MAPK phosphatase export from nucleus, leptomycin B sensitive +namespace: biological_process +def: "Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm." [GOC:ebc] +synonym: "leptomycin B-sensitive MAPK phosphatase export out of nucleus" EXACT [] +synonym: "leptomycin B-sensitive MAPK phosphatase transport from nucleus to cytoplasm" EXACT [] +synonym: "leptomycin B-sensitive MAPK phosphatase-nucleus export" EXACT [] +synonym: "MAPK phosphatase export from cell nucleus, leptomycin B sensitive" EXACT [] +synonym: "MAPK phosphatase export out of nucleus, leptomycin B sensitive" EXACT [] +synonym: "MAPK phosphatase transport from nucleus to cytoplasm, leptomycin B sensitive" EXACT [] +synonym: "MAPK phosphatase-nucleus export, leptomycin B sensitive" EXACT [] +is_a: GO:0045208 ! MAPK phosphatase export from nucleus + +[Term] +id: GO:0045210 +name: FasL biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines." [http://www.copewithcytokines.de/] +synonym: "APT1LG1 biosynthetic process" EXACT [GOC:add] +synonym: "CD178 biosynthetic process" EXACT [GOC:add] +synonym: "CD95L biosynthesis" EXACT [GOC:add] +synonym: "CD95L biosynthetic process" EXACT [GOC:add] +synonym: "fas ligand biosynthetic process" EXACT [GOC:add, PR:000000095] +synonym: "Fas-L biosynthetic process" EXACT [GOC:add] +synonym: "FasL anabolism" EXACT [] +synonym: "FasL biosynthesis" EXACT [] +synonym: "FasL formation" EXACT [] +synonym: "FasL synthesis" EXACT [] +synonym: "FASLG biosynthetic process" EXACT [GOC:add] +is_a: GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0045211 +name: postsynaptic membrane +namespace: cellular_component +def: "A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane." [ISBN:0198506732] +subset: goslim_synapse +synonym: "post-synaptic membrane" EXACT [] +is_a: GO:0097060 ! synaptic membrane +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0045212 +name: neurotransmitter receptor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of neurotransmitter receptors." [GOC:ai] +synonym: "neurotransmitter receptor anabolism" EXACT [] +synonym: "neurotransmitter receptor biosynthesis" EXACT [] +synonym: "neurotransmitter receptor formation" EXACT [] +synonym: "neurotransmitter receptor synthesis" EXACT [] +is_a: GO:0032800 ! receptor biosynthetic process +is_a: GO:0045213 ! neurotransmitter receptor metabolic process + +[Term] +id: GO:0045213 +name: neurotransmitter receptor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving neurotransmitter receptors." [GOC:go_curators] +synonym: "neurotransmitter receptor metabolism" EXACT [] +is_a: GO:0043112 ! receptor metabolic process + +[Term] +id: GO:0045214 +name: sarcomere organization +namespace: biological_process +alt_id: GO:0006938 +def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf] +synonym: "sarcomere alignment" EXACT [] +synonym: "sarcomere organisation" EXACT [] +is_a: GO:0031032 ! actomyosin structure organization +relationship: part_of GO:0030239 ! myofibril assembly + +[Term] +id: GO:0045216 +name: cell-cell junction organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "cell-cell junction assembly and maintenance" EXACT [] +synonym: "cell-cell junction biogenesis" RELATED [] +synonym: "cell-cell junction organisation" EXACT [GOC:mah] +synonym: "intercellular junction assembly and maintenance" EXACT [] +is_a: GO:0034330 ! cell junction organization + +[Term] +id: GO:0045217 +name: cell-cell junction maintenance +namespace: biological_process +def: "The maintenance of junctions between cells." [GOC:ai] +synonym: "intercellular junction maintenance" EXACT [] +is_a: GO:0034331 ! cell junction maintenance +is_a: GO:0045216 ! cell-cell junction organization + +[Term] +id: GO:0045218 +name: zonula adherens maintenance +namespace: biological_process +def: "Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells." [GOC:bf] +is_a: GO:0034334 ! adherens junction maintenance + +[Term] +id: GO:0045219 +name: regulation of FasL biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] +synonym: "regulation of FasL anabolism" EXACT [] +synonym: "regulation of FasL biosynthesis" EXACT [] +synonym: "regulation of FasL formation" EXACT [] +synonym: "regulation of FasL synthesis" EXACT [] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045210 ! FasL biosynthetic process +relationship: regulates GO:0045210 ! FasL biosynthetic process + +[Term] +id: GO:0045220 +name: positive regulation of FasL biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] +synonym: "activation of FasL biosynthetic process" NARROW [] +synonym: "positive regulation of FasL anabolism" EXACT [] +synonym: "positive regulation of FasL biosynthesis" EXACT [] +synonym: "positive regulation of FasL formation" EXACT [] +synonym: "positive regulation of FasL synthesis" EXACT [] +synonym: "stimulation of FasL biosynthetic process" NARROW [] +synonym: "up regulation of FasL biosynthetic process" EXACT [] +synonym: "up-regulation of FasL biosynthetic process" EXACT [] +synonym: "upregulation of FasL biosynthetic process" EXACT [] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0045219 ! regulation of FasL biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045210 ! FasL biosynthetic process +relationship: positively_regulates GO:0045210 ! FasL biosynthetic process + +[Term] +id: GO:0045221 +name: negative regulation of FasL biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] +synonym: "down regulation of FasL biosynthetic process" EXACT [] +synonym: "down-regulation of FasL biosynthetic process" EXACT [] +synonym: "downregulation of FasL biosynthetic process" EXACT [] +synonym: "inhibition of FasL biosynthetic process" NARROW [] +synonym: "negative regulation of FasL anabolism" EXACT [] +synonym: "negative regulation of FasL biosynthesis" EXACT [] +synonym: "negative regulation of FasL formation" EXACT [] +synonym: "negative regulation of FasL synthesis" EXACT [] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0045219 ! regulation of FasL biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045210 ! FasL biosynthetic process +relationship: negatively_regulates GO:0045210 ! FasL biosynthetic process + +[Term] +id: GO:0045222 +name: CD4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." [GOC:go_curators, ISBN:0198506732] +synonym: "CD4 anabolism" EXACT [] +synonym: "CD4 biosynthesis" EXACT [] +synonym: "CD4 formation" EXACT [] +synonym: "CD4 synthesis" EXACT [] +is_a: GO:0009101 ! glycoprotein biosynthetic process + +[Term] +id: GO:0045223 +name: regulation of CD4 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] +synonym: "regulation of CD4 anabolism" EXACT [] +synonym: "regulation of CD4 biosynthesis" EXACT [] +synonym: "regulation of CD4 formation" EXACT [] +synonym: "regulation of CD4 synthesis" EXACT [] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045222 ! CD4 biosynthetic process +relationship: regulates GO:0045222 ! CD4 biosynthetic process + +[Term] +id: GO:0045224 +name: positive regulation of CD4 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] +synonym: "activation of CD4 biosynthetic process" NARROW [] +synonym: "positive regulation of CD4 anabolism" EXACT [] +synonym: "positive regulation of CD4 biosynthesis" EXACT [] +synonym: "positive regulation of CD4 formation" EXACT [] +synonym: "positive regulation of CD4 synthesis" EXACT [] +synonym: "stimulation of CD4 biosynthetic process" NARROW [] +synonym: "up regulation of CD4 biosynthetic process" EXACT [] +synonym: "up-regulation of CD4 biosynthetic process" EXACT [] +synonym: "upregulation of CD4 biosynthetic process" EXACT [] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0045223 ! regulation of CD4 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045222 ! CD4 biosynthetic process +relationship: positively_regulates GO:0045222 ! CD4 biosynthetic process + +[Term] +id: GO:0045225 +name: negative regulation of CD4 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] +synonym: "down regulation of CD4 biosynthetic process" EXACT [] +synonym: "down-regulation of CD4 biosynthetic process" EXACT [] +synonym: "downregulation of CD4 biosynthetic process" EXACT [] +synonym: "inhibition of CD4 biosynthetic process" NARROW [] +synonym: "negative regulation of CD4 anabolism" EXACT [] +synonym: "negative regulation of CD4 biosynthesis" EXACT [] +synonym: "negative regulation of CD4 formation" EXACT [] +synonym: "negative regulation of CD4 synthesis" EXACT [] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0045223 ! regulation of CD4 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045222 ! CD4 biosynthetic process +relationship: negatively_regulates GO:0045222 ! CD4 biosynthetic process + +[Term] +id: GO:0045226 +name: extracellular polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures." [GOC:ai, GOC:go_curators] +synonym: "extracellular polysaccharide anabolism" EXACT [] +synonym: "extracellular polysaccharide biosynthesis" EXACT [] +synonym: "extracellular polysaccharide formation" EXACT [] +synonym: "extracellular polysaccharide synthesis" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0046379 ! extracellular polysaccharide metabolic process + +[Term] +id: GO:0045227 +name: capsule polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi." [GOC:go_curators] +synonym: "capsular polysaccharide biosynthesis" EXACT [] +synonym: "capsular polysaccharide biosynthetic process" EXACT [] +synonym: "capsule polysaccharide anabolism" EXACT [] +synonym: "capsule polysaccharide biosynthesis" EXACT [] +synonym: "capsule polysaccharide formation" EXACT [] +synonym: "capsule polysaccharide synthesis" EXACT [] +is_a: GO:0045226 ! extracellular polysaccharide biosynthetic process +is_a: GO:0045230 ! capsule organization + +[Term] +id: GO:0045228 +name: slime layer polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall." [GOC:go_curators] +synonym: "slime layer polysaccharide anabolism" EXACT [] +synonym: "slime layer polysaccharide biosynthesis" EXACT [] +synonym: "slime layer polysaccharide formation" EXACT [] +synonym: "slime layer polysaccharide synthesis" EXACT [] +is_a: GO:0045226 ! extracellular polysaccharide biosynthetic process +is_a: GO:0045231 ! slime layer organization + +[Term] +id: GO:0045229 +name: external encapsulating structure organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "external encapsulating structure organisation" EXACT [] +synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] +is_a: GO:0016043 ! cellular component organization + +[Term] +id: GO:0045230 +name: capsule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi." [GOC:ai] +subset: goslim_pir +synonym: "capsule organisation" EXACT [] +synonym: "capsule organization and biogenesis" RELATED [] +is_a: GO:0045229 ! external encapsulating structure organization + +[Term] +id: GO:0045231 +name: slime layer organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell." [GOC:ai] +subset: goslim_pir +synonym: "slime layer organisation" EXACT [] +synonym: "slime layer organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045229 ! external encapsulating structure organization + +[Term] +id: GO:0045232 +name: S-layer organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria." [GOC:ai] +synonym: "S-layer organisation" EXACT [] +synonym: "S-layer organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045229 ! external encapsulating structure organization + +[Term] +id: GO:0045233 +name: obsolete natural killer cell receptor activity +namespace: molecular_function +def: "OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family." [GOC:ebc] +comment: This term was made obsolete because the receptor is defined based on its cellular expression pattern, and the definition is inaccurate: receptors on natural killer cells can either activate or inhibit natural killer (NK) cell-mediated cytotoxicity. +synonym: "Ly49i" NARROW [] +synonym: "natural killer cell receptor activity" EXACT [] +synonym: "NK cell receptor activity" EXACT [] +is_obsolete: true +consider: GO:0002769 +consider: GO:0004888 +consider: GO:0030101 + +[Term] +id: GO:0045234 +name: protein palmitoleylation +namespace: biological_process +alt_id: GO:0045235 +def: "The covalent attachment of a palmitoleyl group to a protein." [GOC:ai] +synonym: "protein amino acid palmitoleylation" EXACT [GOC:bf] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0045236 +name: CXCR chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chemokine receptor in the CXCR family." [GOC:ceb, PMID:11910892] +synonym: "alpha chemokine receptor binding" EXACT [] +synonym: "alpha chemokine receptor ligand" NARROW [] +synonym: "C-X-C chemokine receptor ligand" NARROW [] +synonym: "CXC chemokine receptor ligand" NARROW [] +is_a: GO:0042379 ! chemokine receptor binding + +[Term] +id: GO:0045237 +name: CXCR1 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the CXCR1 chemokine receptor." [GOC:ceb, PMID:11910892] +synonym: "CXCR1 chemokine receptor ligand" NARROW [] +is_a: GO:0005153 ! interleukin-8 receptor binding + +[Term] +id: GO:0045238 +name: CXCR2 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the CXCR2 chemokine receptor." [GOC:ceb, PMID:11910892] +synonym: "CXCR2 chemokine receptor ligand" NARROW [] +is_a: GO:0005153 ! interleukin-8 receptor binding + +[Term] +id: GO:0045239 +name: tricarboxylic acid cycle enzyme complex +namespace: cellular_component +def: "Any of the heteromeric enzymes that act in the TCA cycle." [GOC:mah] +subset: goslim_pir +synonym: "TCA cycle enzyme complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045240 +name: dihydrolipoyl dehydrogenase complex +namespace: cellular_component +def: "A protein complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah] +synonym: "2-oxoglutarate dehydrogenase complex" EXACT [] +synonym: "alpha-ketoglutarate dehydrogenase complex" EXACT [] +is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0045241 +name: cytosolic alpha-ketoglutarate dehydrogenase complex +namespace: cellular_component +def: "Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah, GOC:mtg_sensu] +synonym: "2-oxoglutarate dehydrogenase complex" BROAD [] +is_a: GO:0045240 ! dihydrolipoyl dehydrogenase complex +is_a: GO:0045246 ! cytosolic tricarboxylic acid cycle enzyme complex + +[Term] +id: GO:0045242 +name: isocitrate dehydrogenase complex (NAD+) +namespace: cellular_component +def: "Complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah] +is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex +is_a: GO:1990204 ! oxidoreductase complex + +[Term] +id: GO:0045243 +name: cytosolic isocitrate dehydrogenase complex (NAD+) +namespace: cellular_component +def: "Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu] +synonym: "isocitrate dehydrogenase complex (NAD+)" BROAD [] +is_a: GO:0045242 ! isocitrate dehydrogenase complex (NAD+) +is_a: GO:0045246 ! cytosolic tricarboxylic acid cycle enzyme complex +intersection_of: GO:0045242 ! isocitrate dehydrogenase complex (NAD+) +intersection_of: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045244 +name: succinate-CoA ligase complex (GDP-forming) +namespace: cellular_component +alt_id: GO:0008325 +alt_id: GO:0045245 +def: "A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP." [EC:6.2.1.4, GOC:jl] +synonym: "succinyl-CoA synthetase, GDP-forming" EXACT [CORUM:392] +is_a: GO:0030062 ! mitochondrial tricarboxylic acid cycle enzyme complex +is_a: GO:0042709 ! succinate-CoA ligase complex + +[Term] +id: GO:0045246 +name: cytosolic tricarboxylic acid cycle enzyme complex +namespace: cellular_component +def: "Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu] +synonym: "TCA cycle enzyme complex" BROAD [] +synonym: "tricarboxylic acid cycle enzyme complex" BROAD [] +is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045247 +name: cytosolic electron transfer flavoprotein complex +namespace: cellular_component +def: "A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors." [GOC:mtg_sensu, ISBN:0198506732] +is_a: GO:0045251 ! electron transfer flavoprotein complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045248 +name: cytosolic oxoglutarate dehydrogenase complex +namespace: cellular_component +def: "A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2)." [GOC:mtg_sensu, PMID:10848975] +comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. +is_a: GO:0045252 ! oxoglutarate dehydrogenase complex +intersection_of: GO:0045252 ! oxoglutarate dehydrogenase complex +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045249 +name: cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex +namespace: cellular_component +def: "A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex." [GOC:mtg_sensu, PMID:9395502] +comment: See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'. +is_a: GO:0045253 ! pyruvate dehydrogenase (lipoamide) phosphatase complex +intersection_of: GO:0045253 ! pyruvate dehydrogenase (lipoamide) phosphatase complex +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045250 +name: cytosolic pyruvate dehydrogenase complex +namespace: cellular_component +def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order." [GOC:mtg_sensu, ISBN:0471331309, ISBN:0716720094] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. +synonym: "pyruvate dehydrogenase complex (lipoamide)" RELATED [] +is_a: GO:0045254 ! pyruvate dehydrogenase complex +intersection_of: GO:0045254 ! pyruvate dehydrogenase complex +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0045251 +name: electron transfer flavoprotein complex +namespace: cellular_component +def: "A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system." [GOC:bhm, ISBN:0198506732] +subset: goslim_pir +synonym: "ETF complex" EXACT [GOC:bhm] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045252 +name: oxoglutarate dehydrogenase complex +namespace: cellular_component +def: "A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2)." [MetaCyc:CPLX66-42, PMID:10848975] +comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. +subset: goslim_pir +synonym: "dihydrolipoamide S-succinyltransferase complex" EXACT [] +is_a: GO:0045240 ! dihydrolipoyl dehydrogenase complex +is_a: GO:1990234 ! transferase complex + +[Term] +id: GO:0045253 +name: pyruvate dehydrogenase (lipoamide) phosphatase complex +namespace: cellular_component +def: "A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex." [PMID:9395502] +comment: See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'. +subset: goslim_pir +is_a: GO:1903293 ! phosphatase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045254 +name: pyruvate dehydrogenase complex +namespace: cellular_component +alt_id: GO:0009364 +def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3)." [ISBN:0716720094] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. +subset: goslim_pir +synonym: "dihydrolipoyl dehydrogenase complex" BROAD [] +synonym: "pyruvate dehydrogenase complex (lipoamide)" EXACT [] +xref: Wikipedia:Pyruvate_dehydrogenase_complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0045257 +name: succinate dehydrogenase complex (ubiquinone) +namespace: cellular_component +def: "The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration." [GOC:kd, ISBN:0198547684] +is_a: GO:0045281 ! succinate dehydrogenase complex + +[Term] +id: GO:0045258 +name: plasma membrane succinate dehydrogenase complex (ubiquinone) +namespace: cellular_component +def: "The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration." [GOC:kd, GOC:mtg_sensu, ISBN:0198547684] +is_a: GO:0045257 ! succinate dehydrogenase complex (ubiquinone) +is_a: GO:0045282 ! plasma membrane succinate dehydrogenase complex +intersection_of: GO:0045257 ! succinate dehydrogenase complex (ubiquinone) +intersection_of: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0045259 +name: proton-transporting ATP synthase complex +namespace: cellular_component +alt_id: GO:0045255 +def: "A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient." [ISBN:0198547684, ISBN:0716743663] +synonym: "F1-F0 complex" EXACT [] +synonym: "hydrogen-translocating F-type ATPase complex" EXACT [] +synonym: "hydrogen-transporting ATP synthase complex" EXACT [] +synonym: "proton-transporting F-type ATPase complex" RELATED [] +is_a: GO:0016469 ! proton-transporting two-sector ATPase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0045260 +name: plasma membrane proton-transporting ATP synthase complex +namespace: cellular_component +alt_id: GO:0045256 +def: "A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species." [GOC:mah, GOC:mtg_sensu, ISBN:0198547684] +synonym: "hydrogen-translocating F-type ATPase complex" BROAD [] +synonym: "hydrogen-transporting ATP synthase" EXACT [] +synonym: "plasma membrane hydrogen-translocating F-type ATPase complex" EXACT [] +synonym: "proton-transporting ATP synthase complex" BROAD [] +is_a: GO:0045259 ! proton-transporting ATP synthase complex +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045259 ! proton-transporting ATP synthase complex +intersection_of: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0045261 +name: proton-transporting ATP synthase complex, catalytic core F(1) +namespace: cellular_component +def: "The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled." [GOC:mah, PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, F1 sector" EXACT [] +is_a: GO:0033178 ! proton-transporting two-sector ATPase complex, catalytic domain +relationship: part_of GO:0045259 ! proton-transporting ATP synthase complex + +[Term] +id: GO:0045262 +name: plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) +namespace: cellular_component +def: "The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species." [GOC:mah, GOC:mtg_sensu, PMID:10838056] +comment: See also the cellular component term 'plasma membrane ; GO:0005886'. +synonym: "hydrogen-transporting ATP synthase, F1 sector" BROAD [] +synonym: "proton-transporting ATP synthase complex, catalytic core F(1)" BROAD [] +is_a: GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045260 ! plasma membrane proton-transporting ATP synthase complex + +[Term] +id: GO:0045263 +name: proton-transporting ATP synthase complex, coupling factor F(o) +namespace: cellular_component +def: "All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins." [PMID:10838056] +synonym: "hydrogen-transporting ATP synthase complex, coupling factor F(o)" EXACT [GOC:mah] +synonym: "hydrogen-transporting ATP synthase, coupling factor CF(0)" NARROW [] +synonym: "hydrogen-transporting ATP synthase, F0 sector" EXACT [] +synonym: "proton-transporting ATP synthase complex, coupling factor F(0)" EXACT [] +is_a: GO:0033177 ! proton-transporting two-sector ATPase complex, proton-transporting domain +relationship: part_of GO:0045259 ! proton-transporting ATP synthase complex + +[Term] +id: GO:0045264 +name: plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) +namespace: cellular_component +def: "All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins." [GOC:mah, GOC:mtg_sensu, PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, F0 sector" BROAD [] +synonym: "proton-transporting ATP synthase complex, coupling factor F(0)" BROAD [] +synonym: "proton-transporting ATP synthase complex, coupling factor F(o)" BROAD [] +is_a: GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045260 ! plasma membrane proton-transporting ATP synthase complex + +[Term] +id: GO:0045265 +name: proton-transporting ATP synthase, stator stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core." [PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, stator stalk" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o) + +[Term] +id: GO:0045266 +name: plasma membrane proton-transporting ATP synthase, stator stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species." [GOC:mtg_sensu, PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, stator stalk" BROAD [] +synonym: "proton-transporting ATP synthase, stator stalk" BROAD [] +is_a: GO:0045265 ! proton-transporting ATP synthase, stator stalk +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045265 ! proton-transporting ATP synthase, stator stalk +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045264 ! plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) + +[Term] +id: GO:0045267 +name: proton-transporting ATP synthase, catalytic core +namespace: cellular_component +def: "The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase." [PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, catalytic core" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) + +[Term] +id: GO:0045268 +name: plasma membrane proton-transporting ATP synthase, catalytic core +namespace: cellular_component +def: "The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species." [GOC:mtg_sensu, PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, catalytic core" BROAD [] +synonym: "proton-transporting ATP synthase, catalytic core" BROAD [] +is_a: GO:0045267 ! proton-transporting ATP synthase, catalytic core +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045267 ! proton-transporting ATP synthase, catalytic core +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045262 ! plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) + +[Term] +id: GO:0045269 +name: proton-transporting ATP synthase, central stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis." [PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, central stalk" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1) + +[Term] +id: GO:0045270 +name: plasma membrane proton-transporting ATP synthase, central stalk +namespace: cellular_component +def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species." [GOC:mtg_sensu, PMID:10838056] +synonym: "hydrogen-transporting ATP synthase, central stalk" BROAD [] +synonym: "proton-transporting ATP synthase, central stalk" BROAD [] +is_a: GO:0045269 ! proton-transporting ATP synthase, central stalk +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045269 ! proton-transporting ATP synthase, central stalk +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045262 ! plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) + +[Term] +id: GO:0045271 +name: respiratory chain complex I +namespace: cellular_component +alt_id: GO:0045279 +def: "Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex." [GOC:imk, GOC:jid, ISBN:0716749556] +comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (ubiquinone) activity ; GO:0008137'. +synonym: "electron transport complex I" RELATED [] +synonym: "NADH dehydrogenase (ubiquinone) complex" EXACT [] +synonym: "NADH dehydrogenase complex (ubiquinone)" EXACT [] +synonym: "NADH-Q oxidoreductase complex" EXACT [] +is_a: GO:0030964 ! NADH dehydrogenase complex +is_a: GO:0098803 ! respiratory chain complex +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0045272 +name: plasma membrane respiratory chain complex I +namespace: cellular_component +def: "A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species." [GOC:mtg_sensu, ISBN:0198547684] +synonym: "NADH dehydrogenase (ubiquinone) complex" BROAD [] +synonym: "respiratory chain complex I" BROAD [] +is_a: GO:0045271 ! respiratory chain complex I +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045271 ! respiratory chain complex I +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0070470 ! plasma membrane respirasome + +[Term] +id: GO:0045273 +name: respiratory chain complex II +namespace: cellular_component +def: "A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain." [ISBN:0198547684] +subset: goslim_pir +synonym: "electron transport complex II" RELATED [] +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0045274 +name: plasma membrane respiratory chain complex II +namespace: cellular_component +def: "A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species." [GOC:mtg_sensu, ISBN:0198547684] +synonym: "respiratory chain complex II" BROAD [] +is_a: GO:0045273 ! respiratory chain complex II +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045273 ! respiratory chain complex II +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0070470 ! plasma membrane respirasome + +[Term] +id: GO:0045275 +name: respiratory chain complex III +namespace: cellular_component +alt_id: GO:0032842 +alt_id: GO:0045285 +def: "A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species." [PMID:16228398, PMID:16352458, PMID:17200733] +subset: goslim_pir +synonym: "coenzyme Q-cytochrome c oxidoreductase complex" RELATED [] +synonym: "coenzyme Q-cytochrome c reductase complex" RELATED [] +synonym: "complex III" EXACT [] +synonym: "CoQH2-cytochrome c reductase complex" RELATED [] +synonym: "cytochrome bc(1) complex" EXACT [] +synonym: "cytochrome bc1 complex" EXACT [] +synonym: "electron transport complex III" RELATED [] +synonym: "ubiquinol-cytochrome c oxidoreductase complex" EXACT [] +synonym: "ubiquinol-cytochrome-c reductase complex" EXACT [] +xref: Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase +is_a: GO:0070069 ! cytochrome complex +is_a: GO:0098803 ! respiratory chain complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0045276 +name: plasma membrane respiratory chain complex III +namespace: cellular_component +alt_id: GO:0045286 +def: "A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species." [GOC:mtg_sensu, ISBN:0198547684] +synonym: "plasma membrane coenzyme Q-cytochrome c oxidoreductase complex" EXACT [] +synonym: "plasma membrane coenzyme Q-cytochrome c reductase complex" EXACT [] +synonym: "plasma membrane cytochrome bc1 complex" EXACT [] +synonym: "plasma membrane ubiquinol-cytochrome-c reductase complex" EXACT [] +synonym: "respiratory chain complex III" BROAD [] +synonym: "ubiquinol-cytochrome c oxidoreductase complex" BROAD [] +synonym: "ubiquinol-cytochrome-c reductase complex" BROAD [] +is_a: GO:0045275 ! respiratory chain complex III +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045275 ! respiratory chain complex III +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0070470 ! plasma membrane respirasome + +[Term] +id: GO:0045277 +name: respiratory chain complex IV +namespace: cellular_component +alt_id: GO:0045287 +def: "A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2)." [ISBN:0198547684] +subset: goslim_pir +synonym: "cytochrome c oxidase complex" EXACT [] +synonym: "electron transport complex IV" RELATED [] +is_a: GO:0070069 ! cytochrome complex +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0045278 +name: plasma membrane respiratory chain complex IV +namespace: cellular_component +alt_id: GO:0045288 +def: "A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species." [GOC:mtg_sensu, ISBN:0198547684] +synonym: "cytochrome c oxidase complex" BROAD [] +synonym: "respiratory chain complex IV" BROAD [] +is_a: GO:0045277 ! respiratory chain complex IV +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045277 ! respiratory chain complex IV +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0070470 ! plasma membrane respirasome + +[Term] +id: GO:0045281 +name: succinate dehydrogenase complex +namespace: cellular_component +def: "A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones." [GOC:kd, InterPro:IPR000701] +is_a: GO:0098803 ! respiratory chain complex +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0045273 ! respiratory chain complex II + +[Term] +id: GO:0045282 +name: plasma membrane succinate dehydrogenase complex +namespace: cellular_component +def: "A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species." [GOC:kd, GOC:mtg_sensu, InterPro:IPR000701] +synonym: "succinate dehydrogenase complex" BROAD [] +is_a: GO:0045281 ! succinate dehydrogenase complex +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045281 ! succinate dehydrogenase complex +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045274 ! plasma membrane respiratory chain complex II + +[Term] +id: GO:0045283 +name: fumarate reductase complex +namespace: cellular_component +def: "A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone))." [InterPro:IPR003418, InterPro:IPR004224] +comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'. +is_a: GO:0098803 ! respiratory chain complex +relationship: part_of GO:0045273 ! respiratory chain complex II + +[Term] +id: GO:0045284 +name: plasma membrane fumarate reductase complex +namespace: cellular_component +def: "A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species." [GOC:mtg_sensu, InterPro:IPR003418, InterPro:IPR004224] +comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'. +synonym: "fumarate reductase complex" BROAD [] +is_a: GO:0045283 ! fumarate reductase complex +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0045283 ! fumarate reductase complex +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0045274 ! plasma membrane respiratory chain complex II + +[Term] +id: GO:0045289 +name: luciferin monooxygenase activity +namespace: molecular_function +def: "Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation." [GOC:bf] +synonym: "luciferase activity" EXACT [] +synonym: "luciferase monooxygenase activity" RELATED [] +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0045290 +name: D-arabinose 1-dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+." [EC:1.1.1.117] +synonym: "D-arabinose:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.117] +xref: EC:1.1.1.117 +xref: MetaCyc:1.1.1.117-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0045291 +name: mRNA trans splicing, SL addition +namespace: biological_process +def: "The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body." [GOC:krc, ISBN:0879695897, PMID:2675423] +synonym: "nuclear mRNA trans splicing, SL addition" EXACT [GOC:vw] +synonym: "nuclear mRNA trans splicing, spliced leader addition" EXACT [] +is_a: GO:0000365 ! mRNA trans splicing, via spliceosome + +[Term] +id: GO:0045292 +name: mRNA cis splicing, via spliceosome +namespace: biological_process +def: "The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript." [GOC:krc, ISBN:0879695897, PMID:18458335] +synonym: "nuclear mRNA cis splicing, via spliceosome" EXACT [GOC:vw] +synonym: "nuclear mRNA cis splicing, via U2-type spliceosome" NARROW [] +synonym: "splicing" BROAD [GOC:vw] +is_a: GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0045293 +name: mRNA editing complex +namespace: cellular_component +def: "A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes." [http://www.ejbiotechnology.info/content/vol1/issue1/full/4/, PMID:11564867, PMID:12139607, PMID:24316715] +subset: goslim_pir +synonym: "editosome" EXACT [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0045294 +name: alpha-catenin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the alpha subunit of the catenin complex." [GOC:bf] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0045295 +name: gamma-catenin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the gamma subunit of the catenin complex." [GOC:bf] +synonym: "plakoglobin binding" EXACT [GOC:BHF] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:50557 + +[Term] +id: GO:0045296 +name: cadherin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion." [GOC:bf] +is_a: GO:0050839 ! cell adhesion molecule binding + +[Term] +id: GO:0045297 +name: obsolete post-mating behavior +namespace: biological_process +def: "OBSOLETE. The specific behavior of an organism following mating." [GOC:bf, GOC:pr] +comment: This term was obsoleted because it was not precisely defined. +synonym: "post-mating behaviour" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045298 +name: tubulin complex +namespace: cellular_component +def: "A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly." [ISBN:0716731363] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0045299 +name: otolith mineralization +namespace: biological_process +def: "The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear." [GOC:dsf, PMID:15581873] +is_a: GO:0031214 ! biomineral tissue development +relationship: part_of GO:0048840 ! otolith development + +[Term] +id: GO:0045300 +name: acyl-[acyl-carrier-protein] desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin." [EC:1.14.19.2] +comment: Note that this function was formerly EC:1.14.99.6. +synonym: "acyl-[acyl-carrier protein] desaturase activity" EXACT [] +synonym: "acyl-acyl-carrier-protein desaturase activity" EXACT [EC:1.14.19.2] +synonym: "acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.2] +synonym: "stearyl acyl carrier protein desaturase activity" EXACT [EC:1.14.19.2] +synonym: "stearyl-ACP desaturase activity" EXACT [EC:1.14.19.2] +xref: EC:1.14.19.2 +xref: MetaCyc:1.14.19.2-RXN +xref: MetaCyc:PWY-5147 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0045301 +name: tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin." [GOC:mlg, PMID:8253666] +synonym: "2-methylthio-cis-ribozeatin hydroxylase activity" EXACT [] +synonym: "tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity" EXACT [] +synonym: "tRNA-(ms2io6A)-hydroxylase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0002195 ! 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis + +[Term] +id: GO:0045302 +name: choloylglycine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine." [EC:3.5.1.24] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity" EXACT [EC:3.5.1.24] +synonym: "bile salt hydrolase activity" EXACT [EC:3.5.1.24] +synonym: "choloyltaurine hydrolase activity" EXACT [EC:3.5.1.24] +synonym: "glycocholase activity" EXACT [EC:3.5.1.24] +xref: EC:3.5.1.24 +xref: MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN +xref: RHEA:19353 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0045303 +name: diaminobutyrate-2-oxoglutarate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate." [EC:2.6.1.76, RHEA:11160] +synonym: "2,4-diaminobutyrate 4-aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "DAB aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "DABA aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "diaminibutyric acid aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "diaminobutyrate transaminase activity" EXACT [EC:2.6.1.76] +synonym: "diaminobutyrate--2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "EctB" RELATED [EC:2.6.1.76] +synonym: "L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] +synonym: "L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] +xref: EC:2.6.1.76 +xref: KEGG_REACTION:R06977 +xref: MetaCyc:R101-RXN +xref: RHEA:11160 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0045304 +name: regulation of establishment of competence for transformation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome." [GOC:mlg] +synonym: "regulator of establishment of competence for transformation activity" RELATED [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032104 ! regulation of response to extracellular stimulus +is_a: GO:0043900 ! regulation of multi-organism process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030420 ! establishment of competence for transformation +relationship: regulates GO:0030420 ! establishment of competence for transformation + +[Term] +id: GO:0045305 +name: obsolete regulator of establishment of competence for transformation activity +namespace: molecular_function +def: "OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation." [GOC:mlg] +comment: This term was made obsolete because it does not represent a true function. +synonym: "regulator of establishment of competence for transformation activity" EXACT [] +is_obsolete: true +replaced_by: GO:0045304 + +[Term] +id: GO:0045306 +name: obsolete inhibitor of the establishment of competence for transformation activity +namespace: molecular_function +def: "OBSOLETE. Inhibits the establishment of competence for transformation." [GOC:mlg] +comment: This term was made obsolete because it does not represent a true function. +synonym: "inhibitor of the establishment of competence for transformation activity" EXACT [] +is_obsolete: true +replaced_by: GO:0045808 + +[Term] +id: GO:0045307 +name: obsolete activator of the establishment of competence for transformation activity +namespace: molecular_function +def: "OBSOLETE. Activates the establishment of competence for transformation." [GOC:mlg] +comment: This term was made obsolete because it does not represent a true function. +synonym: "activator of the establishment of competence for transformation activity" EXACT [] +is_obsolete: true +replaced_by: GO:0045809 + +[Term] +id: GO:0045309 +name: protein phosphorylated amino acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein." [GOC:go_curators] +synonym: "phosphoprotein amino acid binding" RELATED [] +is_a: GO:0051219 ! phosphoprotein binding + +[Term] +id: GO:0045310 +name: obsolete phosphoserine/phosphothreonine binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein." [GOC:go_curators] +comment: This term was made obsolete because it represents two functions. +synonym: "phosphoserine/phosphothreonine binding" EXACT [] +is_obsolete: true +consider: GO:0050815 +consider: GO:0050816 + +[Term] +id: GO:0045311 +name: invasive growth in response to pheromone +namespace: biological_process +def: "The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus." [GOC:ai, GOC:dph, GOC:mcc] +is_a: GO:0036267 ! invasive filamentous growth +relationship: part_of GO:0019236 ! response to pheromone + +[Term] +id: GO:0045312 +name: nor-spermidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:go_curators] +synonym: "nor-spermidine anabolism" EXACT [] +synonym: "nor-spermidine biosynthesis" EXACT [] +synonym: "nor-spermidine formation" EXACT [] +synonym: "nor-spermidine synthesis" EXACT [] +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:0046204 ! nor-spermidine metabolic process + +[Term] +id: GO:0045313 +name: rhabdomere membrane biogenesis +namespace: biological_process +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane." [GOC:jl] +is_a: GO:0044091 ! membrane biogenesis +relationship: part_of GO:0042052 ! rhabdomere development + +[Term] +id: GO:0045314 +name: regulation of compound eye photoreceptor development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] +synonym: "regulation of eye photoreceptor development" BROAD [] +is_a: GO:0042478 ! regulation of eye photoreceptor cell development +is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0046532 ! regulation of photoreceptor cell differentiation +relationship: regulates GO:0042051 ! compound eye photoreceptor development + +[Term] +id: GO:0045315 +name: positive regulation of compound eye photoreceptor development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] +synonym: "activation of eye photoreceptor development" BROAD [] +synonym: "positive regulation of eye photoreceptor development" BROAD [] +synonym: "stimulation of eye photoreceptor development" BROAD [] +synonym: "up regulation of eye photoreceptor development" BROAD [] +synonym: "up-regulation of eye photoreceptor development" BROAD [] +synonym: "upregulation of eye photoreceptor development" BROAD [] +is_a: GO:0042479 ! positive regulation of eye photoreceptor cell development +is_a: GO:0045314 ! regulation of compound eye photoreceptor development +is_a: GO:0110117 ! positive regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042051 ! compound eye photoreceptor development +relationship: positively_regulates GO:0042051 ! compound eye photoreceptor development + +[Term] +id: GO:0045316 +name: negative regulation of compound eye photoreceptor development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] +synonym: "down regulation of eye photoreceptor development" BROAD [] +synonym: "down-regulation of eye photoreceptor development" BROAD [] +synonym: "downregulation of eye photoreceptor development" BROAD [] +synonym: "inhibition of eye photoreceptor development" BROAD [] +synonym: "negative regulation of eye photoreceptor development" BROAD [] +is_a: GO:0042480 ! negative regulation of eye photoreceptor cell development +is_a: GO:0045314 ! regulation of compound eye photoreceptor development +is_a: GO:0110118 ! negative regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042051 ! compound eye photoreceptor development +relationship: negatively_regulates GO:0042051 ! compound eye photoreceptor development + +[Term] +id: GO:0045317 +name: equator specification +namespace: biological_process +def: "The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves." [GOC:bf] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0042067 ! establishment of ommatidial planar polarity + +[Term] +id: GO:0045319 +name: obsolete SRP-independent cotranslational protein-membrane targeting, translocation +namespace: biological_process +def: "OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition." [GOC:ai] +comment: This term was made obsolete because there is no evidence for the existence of this process. +synonym: "SRP-independent cotranslational membrane targeting, translocation" EXACT [] +synonym: "SRP-independent cotranslational protein-membrane targeting, translocation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045320 +name: chloroplast proton-transporting ATP synthase complex +namespace: cellular_component +def: "A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation." [GOC:mtg_sensu, GOC:pj, ISBN:0716743663] +synonym: "chloroplast hydrogen-translocating F-type ATPase complex" EXACT [] +synonym: "chloroplast proton-transporting F-type ATPase complex" EXACT [] +synonym: "hydrogen-translocating F-type ATPase complex" BROAD [] +is_a: GO:0045259 ! proton-transporting ATP synthase complex +is_a: GO:0098807 ! chloroplast thylakoid membrane protein complex +intersection_of: GO:0045259 ! proton-transporting ATP synthase complex +intersection_of: part_of GO:0009507 ! chloroplast + +[Term] +id: GO:0045321 +name: leukocyte activation +namespace: biological_process +def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] +synonym: "immune cell activation" EXACT [] +synonym: "leucocyte activation" EXACT [] +xref: Wikipedia:Immunologic_activation +is_a: GO:0001775 ! cell activation +is_a: GO:0002376 ! immune system process + +[Term] +id: GO:0045322 +name: unmethylated CpG binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters." [GOC:ai, PMID:10688657] +is_a: GO:0043565 ! sequence-specific DNA binding + +[Term] +id: GO:0045323 +name: interleukin-1 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-1; comprises an alpha and a beta subunit." [GOC:mah, InterPro:IPR004075] +synonym: "IL-1 receptor complex" EXACT [GOC:add] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0045324 +name: late endosome to vacuole transport +namespace: biological_process +def: "The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport." [PMID:11872141] +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0045325 +name: peptidyl-tryptophan hydroxylation +namespace: biological_process +def: "The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan." [RESID:AA0322] +xref: RESID:AA0322 +is_a: GO:0018211 ! peptidyl-tryptophan modification + +[Term] +id: GO:0045326 +name: protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine." [RESID:AA0323] +synonym: "DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine" EXACT [GOC:mah] +xref: RESID:AA0323 +is_a: GO:0045327 ! protein-DNA covalent cross-linking via peptidyl-tyrosine + +[Term] +id: GO:0045327 +name: protein-DNA covalent cross-linking via peptidyl-tyrosine +namespace: biological_process +def: "The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue." [GOC:jsg] +synonym: "DNA-protein covalent cross-linking via peptidyl-tyrosine" EXACT [GOC:mah] +is_a: GO:0018142 ! protein-DNA covalent cross-linking +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0045328 +name: cytochrome P450 4A1-heme linkage +namespace: biological_process +def: "The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester." [GOC:cjm, RESID:AA0324] +synonym: "cytochrome P450 4A1-haem linkage" EXACT [] +xref: RESID:AA0324 +is_a: GO:0017003 ! protein-heme linkage +relationship: part_of GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0045329 +name: carnitine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:jl, ISBN:0198506732] +synonym: "carnitine anabolism" EXACT [] +synonym: "carnitine biosynthesis" EXACT [] +synonym: "carnitine formation" EXACT [] +synonym: "carnitine synthesis" EXACT [] +synonym: "vitamin Bt biosynthesis" EXACT [] +synonym: "vitamin Bt biosynthetic process" EXACT [] +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0009437 ! carnitine metabolic process + +[Term] +id: GO:0045330 +name: aspartyl esterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue." [GOC:mah, UniProtKB-KW:KW-0063] +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0045331 +name: obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate." [EC:1.12.99.2] +comment: This term was made obsolete because it represents two activities. +synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity" EXACT [] +synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity" EXACT [] +synonym: "heterodisulfide reductase activity" EXACT [] +is_obsolete: true +consider: GO:0051911 +consider: GO:0051912 + +[Term] +id: GO:0045332 +name: phospholipid translocation +namespace: biological_process +def: "The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet." [ISBN:0815316194, PMID:16452632, PMID:20043909, PMID:20302864] +comment: Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'. +synonym: "flippase" RELATED [] +synonym: "phospholipid scrambling" RELATED [] +is_a: GO:0015914 ! phospholipid transport +is_a: GO:0034204 ! lipid translocation + +[Term] +id: GO:0045333 +name: cellular respiration +namespace: biological_process +def: "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)." [GOC:das, ISBN:0140513590, ISBN:0198506732] +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +subset: goslim_yeast +synonym: "oxidative metabolic process" EXACT [] +synonym: "oxidative metabolism" EXACT [] +synonym: "respiration" BROAD [] +xref: Wikipedia:Cellular_respiration +is_a: GO:0015980 ! energy derivation by oxidation of organic compounds + +[Term] +id: GO:0045334 +name: clathrin-coated endocytic vesicle +namespace: cellular_component +def: "A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance." [GOC:go_curators] +xref: NIF_Subcellular:sao1243595998 +is_a: GO:0030136 ! clathrin-coated vesicle +is_a: GO:0030139 ! endocytic vesicle + +[Term] +id: GO:0045335 +name: phagocytic vesicle +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis." [GOC:go_curators, ISBN:0198506732] +synonym: "phagosome" EXACT [] +xref: Wikipedia:Phagosome +is_a: GO:0030139 ! endocytic vesicle + +[Term] +id: GO:0045336 +name: clathrin-coated phagocytic vesicle +namespace: cellular_component +def: "A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis." [GOC:go_curators, ISBN:0198506732] +synonym: "clathrin-coated phagosome" EXACT [] +is_a: GO:0045334 ! clathrin-coated endocytic vesicle +is_a: GO:0045335 ! phagocytic vesicle + +[Term] +id: GO:0045337 +name: farnesyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of farnesyl diphosphate." [GOC:jl] +synonym: "farnesyl diphosphate anabolism" EXACT [] +synonym: "farnesyl diphosphate biosynthesis" EXACT [] +synonym: "farnesyl diphosphate formation" EXACT [] +synonym: "farnesyl diphosphate synthesis" EXACT [] +xref: MetaCyc:PWY-5123 +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016114 ! terpenoid biosynthetic process +is_a: GO:0045338 ! farnesyl diphosphate metabolic process + +[Term] +id: GO:0045338 +name: farnesyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation." [GOC:go_curators] +synonym: "farnesyl diphosphate metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0045339 +name: farnesyl diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate." [GOC:go_curators] +synonym: "farnesyl diphosphate breakdown" EXACT [] +synonym: "farnesyl diphosphate catabolism" EXACT [] +synonym: "farnesyl diphosphate degradation" EXACT [] +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0016115 ! terpenoid catabolic process +is_a: GO:0045338 ! farnesyl diphosphate metabolic process + +[Term] +id: GO:0045340 +name: mercury ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with mercury (Hg) ions." [GOC:go_curators] +synonym: "mercury binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0045341 +name: MHC class I biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I." [GOC:go_curators] +synonym: "major histocompatibility complex class I biosynthesis" EXACT [] +synonym: "major histocompatibility complex class I biosynthetic process" EXACT [] +synonym: "MHC class I anabolism" EXACT [] +synonym: "MHC class I biosynthesis" EXACT [] +synonym: "MHC class I formation" EXACT [] +synonym: "MHC class I synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0045342 +name: MHC class II biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II." [GOC:go_curators] +synonym: "major histocompatibility complex class II biosynthesis" EXACT [] +synonym: "major histocompatibility complex class II biosynthetic process" EXACT [] +synonym: "MHC class II anabolism" EXACT [] +synonym: "MHC class II biosynthesis" EXACT [] +synonym: "MHC class II formation" EXACT [] +synonym: "MHC class II synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0045343 +name: regulation of MHC class I biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I." [GOC:go_curators] +synonym: "regulation of major histocompatibility complex class I biosynthesis" EXACT [] +synonym: "regulation of major histocompatibility complex class I biosynthetic process" EXACT [] +synonym: "regulation of MHC class I anabolism" EXACT [] +synonym: "regulation of MHC class I biosynthesis" EXACT [] +synonym: "regulation of MHC class I formation" EXACT [] +synonym: "regulation of MHC class I synthesis" EXACT [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045341 ! MHC class I biosynthetic process +relationship: regulates GO:0045341 ! MHC class I biosynthetic process + +[Term] +id: GO:0045344 +name: negative regulation of MHC class I biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I." [GOC:go_curators] +synonym: "down regulation of MHC class I biosynthetic process" EXACT [] +synonym: "down-regulation of MHC class I biosynthetic process" EXACT [] +synonym: "downregulation of MHC class I biosynthetic process" EXACT [] +synonym: "inhibition of MHC class I biosynthetic process" NARROW [] +synonym: "negative regulation of major histocompatibility complex class I biosynthesis" EXACT [] +synonym: "negative regulation of major histocompatibility complex class I biosynthetic process" EXACT [] +synonym: "negative regulation of MHC class I anabolism" EXACT [] +synonym: "negative regulation of MHC class I biosynthesis" EXACT [] +synonym: "negative regulation of MHC class I formation" EXACT [] +synonym: "negative regulation of MHC class I synthesis" EXACT [] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0045343 ! regulation of MHC class I biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045341 ! MHC class I biosynthetic process +relationship: negatively_regulates GO:0045341 ! MHC class I biosynthetic process + +[Term] +id: GO:0045345 +name: positive regulation of MHC class I biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I." [GOC:go_curators] +synonym: "activation of MHC class I biosynthetic process" NARROW [] +synonym: "positive regulation of major histocompatibility complex class I biosynthesis" EXACT [] +synonym: "positive regulation of major histocompatibility complex class I biosynthetic process" EXACT [] +synonym: "positive regulation of MHC class I anabolism" EXACT [] +synonym: "positive regulation of MHC class I biosynthesis" EXACT [] +synonym: "positive regulation of MHC class I formation" EXACT [] +synonym: "positive regulation of MHC class I synthesis" EXACT [] +synonym: "stimulation of MHC class I biosynthetic process" NARROW [] +synonym: "up regulation of MHC class I biosynthetic process" EXACT [] +synonym: "up-regulation of MHC class I biosynthetic process" EXACT [] +synonym: "upregulation of MHC class I biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0045343 ! regulation of MHC class I biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045341 ! MHC class I biosynthetic process +relationship: positively_regulates GO:0045341 ! MHC class I biosynthetic process + +[Term] +id: GO:0045346 +name: regulation of MHC class II biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II." [GOC:go_curators] +synonym: "regulation of major histocompatibility complex class II biosynthesis" EXACT [] +synonym: "regulation of major histocompatibility complex class II biosynthetic process" EXACT [] +synonym: "regulation of MHC class II anabolism" EXACT [] +synonym: "regulation of MHC class II biosynthesis" EXACT [] +synonym: "regulation of MHC class II formation" EXACT [] +synonym: "regulation of MHC class II synthesis" EXACT [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045342 ! MHC class II biosynthetic process +relationship: regulates GO:0045342 ! MHC class II biosynthetic process + +[Term] +id: GO:0045347 +name: negative regulation of MHC class II biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II." [GOC:go_curators] +synonym: "down regulation of MHC class II biosynthetic process" EXACT [] +synonym: "down-regulation of MHC class II biosynthetic process" EXACT [] +synonym: "downregulation of MHC class II biosynthetic process" EXACT [] +synonym: "inhibition of MHC class II biosynthetic process" NARROW [] +synonym: "negative regulation of major histocompatibility complex class II biosynthesis" EXACT [] +synonym: "negative regulation of major histocompatibility complex class II biosynthetic process" EXACT [] +synonym: "negative regulation of MHC class II anabolism" EXACT [] +synonym: "negative regulation of MHC class II biosynthesis" EXACT [] +synonym: "negative regulation of MHC class II formation" EXACT [] +synonym: "negative regulation of MHC class II synthesis" EXACT [] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0045346 ! regulation of MHC class II biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045342 ! MHC class II biosynthetic process +relationship: negatively_regulates GO:0045342 ! MHC class II biosynthetic process + +[Term] +id: GO:0045348 +name: positive regulation of MHC class II biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II." [GOC:go_curators] +synonym: "activation of MHC class II biosynthetic process" NARROW [] +synonym: "positive regulation of major histocompatibility complex class II biosynthesis" EXACT [] +synonym: "positive regulation of major histocompatibility complex class II biosynthetic process" EXACT [] +synonym: "positive regulation of MHC class II anabolism" EXACT [] +synonym: "positive regulation of MHC class II biosynthesis" EXACT [] +synonym: "positive regulation of MHC class II formation" EXACT [] +synonym: "positive regulation of MHC class II synthesis" EXACT [] +synonym: "stimulation of MHC class II biosynthetic process" NARROW [] +synonym: "up regulation of MHC class II biosynthetic process" EXACT [] +synonym: "up-regulation of MHC class II biosynthetic process" EXACT [] +synonym: "upregulation of MHC class II biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0045346 ! regulation of MHC class II biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045342 ! MHC class II biosynthetic process +relationship: positively_regulates GO:0045342 ! MHC class II biosynthetic process + +[Term] +id: GO:0045349 +name: interferon-alpha biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] +synonym: "IFN-alpha biosynthesis" EXACT [] +synonym: "IFN-alpha biosynthetic process" EXACT [] +synonym: "interferon-alpha anabolism" EXACT [] +synonym: "interferon-alpha biosynthesis" EXACT [] +synonym: "interferon-alpha formation" EXACT [] +synonym: "interferon-alpha synthesis" EXACT [] +is_a: GO:0045351 ! type I interferon biosynthetic process +relationship: part_of GO:0032607 ! interferon-alpha production + +[Term] +id: GO:0045350 +name: interferon-beta biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] +synonym: "IFN-beta biosynthesis" EXACT [] +synonym: "IFN-beta biosynthetic process" EXACT [] +synonym: "IFNB biosynthetic process" EXACT [GOC:mah] +synonym: "interferon-beta anabolism" EXACT [] +synonym: "interferon-beta biosynthesis" EXACT [] +synonym: "interferon-beta formation" EXACT [] +synonym: "interferon-beta synthesis" EXACT [] +is_a: GO:0045351 ! type I interferon biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032608 ! interferon-beta production + +[Term] +id: GO:0045351 +name: type I interferon biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any type I interferon. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add] +synonym: "interferon type I biosynthetic process" EXACT [] +synonym: "type I interferon anabolism" EXACT [] +synonym: "type I interferon biosynthesis" EXACT [] +synonym: "type I interferon formation" EXACT [] +synonym: "type I interferon synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032606 ! type I interferon production + +[Term] +id: GO:0045352 +name: interleukin-1 type I receptor antagonist activity +namespace: molecular_function +def: "Blocks the binding of interleukin-1 to interleukin-1 type I receptors." [GOC:ebc] +synonym: "IL-1ra type I" EXACT [] +is_a: GO:0005152 ! interleukin-1 receptor antagonist activity + +[Term] +id: GO:0045353 +name: interleukin-1 type II receptor antagonist activity +namespace: molecular_function +def: "Blocks the binding of interleukin-1 to interleukin-1 type II receptors." [GOC:ebc] +synonym: "IL-1ra type II" EXACT [] +is_a: GO:0005152 ! interleukin-1 receptor antagonist activity + +[Term] +id: GO:0045354 +name: regulation of interferon-alpha biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] +synonym: "regulation of interferon-alpha anabolism" EXACT [] +synonym: "regulation of interferon-alpha biosynthesis" EXACT [] +synonym: "regulation of interferon-alpha formation" EXACT [] +synonym: "regulation of interferon-alpha synthesis" EXACT [] +is_a: GO:0032647 ! regulation of interferon-alpha production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045349 ! interferon-alpha biosynthetic process +relationship: regulates GO:0045349 ! interferon-alpha biosynthetic process + +[Term] +id: GO:0045355 +name: negative regulation of interferon-alpha biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] +synonym: "down regulation of interferon-alpha biosynthetic process" EXACT [] +synonym: "down-regulation of interferon-alpha biosynthetic process" EXACT [] +synonym: "downregulation of interferon-alpha biosynthetic process" EXACT [] +synonym: "inhibition of interferon-alpha biosynthetic process" NARROW [] +synonym: "negative regulation of interferon-alpha anabolism" EXACT [] +synonym: "negative regulation of interferon-alpha biosynthesis" EXACT [] +synonym: "negative regulation of interferon-alpha formation" EXACT [] +synonym: "negative regulation of interferon-alpha synthesis" EXACT [] +is_a: GO:0032687 ! negative regulation of interferon-alpha production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045354 ! regulation of interferon-alpha biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045349 ! interferon-alpha biosynthetic process +relationship: negatively_regulates GO:0045349 ! interferon-alpha biosynthetic process + +[Term] +id: GO:0045356 +name: positive regulation of interferon-alpha biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] +synonym: "activation of interferon-alpha biosynthetic process" NARROW [] +synonym: "positive regulation of interferon-alpha anabolism" EXACT [] +synonym: "positive regulation of interferon-alpha biosynthesis" EXACT [] +synonym: "positive regulation of interferon-alpha formation" EXACT [] +synonym: "positive regulation of interferon-alpha synthesis" EXACT [] +synonym: "stimulation of interferon-alpha biosynthetic process" NARROW [] +synonym: "up regulation of interferon-alpha biosynthetic process" EXACT [] +synonym: "up-regulation of interferon-alpha biosynthetic process" EXACT [] +synonym: "upregulation of interferon-alpha biosynthetic process" EXACT [] +is_a: GO:0032727 ! positive regulation of interferon-alpha production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045354 ! regulation of interferon-alpha biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045349 ! interferon-alpha biosynthetic process +relationship: positively_regulates GO:0045349 ! interferon-alpha biosynthetic process + +[Term] +id: GO:0045357 +name: regulation of interferon-beta biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] +synonym: "regulation of interferon-beta anabolism" EXACT [] +synonym: "regulation of interferon-beta biosynthesis" EXACT [] +synonym: "regulation of interferon-beta formation" EXACT [] +synonym: "regulation of interferon-beta synthesis" EXACT [] +is_a: GO:0032648 ! regulation of interferon-beta production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045350 ! interferon-beta biosynthetic process +relationship: regulates GO:0045350 ! interferon-beta biosynthetic process + +[Term] +id: GO:0045358 +name: negative regulation of interferon-beta biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] +synonym: "down regulation of interferon-beta biosynthetic process" EXACT [] +synonym: "down-regulation of interferon-beta biosynthetic process" EXACT [] +synonym: "downregulation of interferon-beta biosynthetic process" EXACT [] +synonym: "inhibition of interferon-beta biosynthetic process" NARROW [] +synonym: "negative regulation of interferon-beta anabolism" EXACT [] +synonym: "negative regulation of interferon-beta biosynthesis" EXACT [] +synonym: "negative regulation of interferon-beta formation" EXACT [] +synonym: "negative regulation of interferon-beta synthesis" EXACT [] +is_a: GO:0032688 ! negative regulation of interferon-beta production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045357 ! regulation of interferon-beta biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045350 ! interferon-beta biosynthetic process +relationship: negatively_regulates GO:0045350 ! interferon-beta biosynthetic process + +[Term] +id: GO:0045359 +name: positive regulation of interferon-beta biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] +synonym: "activation of interferon-beta biosynthetic process" NARROW [] +synonym: "positive regulation of interferon-beta anabolism" EXACT [] +synonym: "positive regulation of interferon-beta biosynthesis" EXACT [] +synonym: "positive regulation of interferon-beta formation" EXACT [] +synonym: "positive regulation of interferon-beta synthesis" EXACT [] +synonym: "stimulation of interferon-beta biosynthetic process" NARROW [] +synonym: "up regulation of interferon-beta biosynthetic process" EXACT [] +synonym: "up-regulation of interferon-beta biosynthetic process" EXACT [] +synonym: "upregulation of interferon-beta biosynthetic process" EXACT [] +is_a: GO:0032728 ! positive regulation of interferon-beta production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045357 ! regulation of interferon-beta biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045350 ! interferon-beta biosynthetic process +relationship: positively_regulates GO:0045350 ! interferon-beta biosynthetic process + +[Term] +id: GO:0045360 +name: regulation of interleukin-1 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] +synonym: "regulation of IL-1 biosynthesis" EXACT [] +synonym: "regulation of IL-1 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-1 anabolism" EXACT [] +synonym: "regulation of interleukin-1 biosynthesis" EXACT [] +synonym: "regulation of interleukin-1 formation" EXACT [] +synonym: "regulation of interleukin-1 synthesis" EXACT [] +is_a: GO:0032652 ! regulation of interleukin-1 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042222 ! interleukin-1 biosynthetic process +relationship: regulates GO:0042222 ! interleukin-1 biosynthetic process + +[Term] +id: GO:0045361 +name: negative regulation of interleukin-1 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] +synonym: "down regulation of interleukin-1 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-1 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-1 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-1 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-1 biosynthesis" EXACT [] +synonym: "negative regulation of IL-1 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-1 anabolism" EXACT [] +synonym: "negative regulation of interleukin-1 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-1 formation" EXACT [] +synonym: "negative regulation of interleukin-1 synthesis" EXACT [] +is_a: GO:0032692 ! negative regulation of interleukin-1 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045360 ! regulation of interleukin-1 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042222 ! interleukin-1 biosynthetic process +relationship: negatively_regulates GO:0042222 ! interleukin-1 biosynthetic process + +[Term] +id: GO:0045362 +name: positive regulation of interleukin-1 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] +synonym: "activation of interleukin-1 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-1 biosynthesis" EXACT [] +synonym: "positive regulation of IL-1 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-1 anabolism" EXACT [] +synonym: "positive regulation of interleukin-1 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-1 formation" EXACT [] +synonym: "positive regulation of interleukin-1 synthesis" EXACT [] +synonym: "stimulation of interleukin-1 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-1 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-1 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-1 biosynthetic process" EXACT [] +is_a: GO:0032732 ! positive regulation of interleukin-1 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045360 ! regulation of interleukin-1 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042222 ! interleukin-1 biosynthetic process +relationship: positively_regulates GO:0042222 ! interleukin-1 biosynthetic process + +[Term] +id: GO:0045363 +name: regulation of interleukin-11 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] +synonym: "regulation of IL-11 biosynthesis" EXACT [] +synonym: "regulation of IL-11 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-11 anabolism" EXACT [] +synonym: "regulation of interleukin-11 biosynthesis" EXACT [] +synonym: "regulation of interleukin-11 formation" EXACT [] +synonym: "regulation of interleukin-11 synthesis" EXACT [] +is_a: GO:0032654 ! regulation of interleukin-11 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042230 ! interleukin-11 biosynthetic process +relationship: regulates GO:0042230 ! interleukin-11 biosynthetic process + +[Term] +id: GO:0045364 +name: negative regulation of interleukin-11 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] +synonym: "down regulation of interleukin-11 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-11 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-11 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-11 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-11 biosynthesis" EXACT [] +synonym: "negative regulation of IL-11 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-11 anabolism" EXACT [] +synonym: "negative regulation of interleukin-11 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-11 formation" EXACT [] +synonym: "negative regulation of interleukin-11 synthesis" EXACT [] +is_a: GO:0032694 ! negative regulation of interleukin-11 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045363 ! regulation of interleukin-11 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042230 ! interleukin-11 biosynthetic process +relationship: negatively_regulates GO:0042230 ! interleukin-11 biosynthetic process + +[Term] +id: GO:0045365 +name: positive regulation of interleukin-11 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] +synonym: "activation of interleukin-11 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-11 biosynthesis" EXACT [] +synonym: "positive regulation of IL-11 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-11 anabolism" EXACT [] +synonym: "positive regulation of interleukin-11 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-11 formation" EXACT [] +synonym: "positive regulation of interleukin-11 synthesis" EXACT [] +synonym: "stimulation of interleukin-11 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-11 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-11 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-11 biosynthetic process" EXACT [] +is_a: GO:0032734 ! positive regulation of interleukin-11 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045363 ! regulation of interleukin-11 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042230 ! interleukin-11 biosynthetic process +relationship: positively_regulates GO:0042230 ! interleukin-11 biosynthetic process + +[Term] +id: GO:0045366 +name: regulation of interleukin-13 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] +synonym: "regulation of IL-13 biosynthesis" EXACT [] +synonym: "regulation of IL-13 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-13 anabolism" EXACT [] +synonym: "regulation of interleukin-13 biosynthesis" EXACT [] +synonym: "regulation of interleukin-13 formation" EXACT [] +synonym: "regulation of interleukin-13 synthesis" EXACT [] +is_a: GO:0032656 ! regulation of interleukin-13 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042231 ! interleukin-13 biosynthetic process +relationship: regulates GO:0042231 ! interleukin-13 biosynthetic process + +[Term] +id: GO:0045367 +name: negative regulation of interleukin-13 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] +synonym: "down regulation of interleukin-13 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-13 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-13 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-13 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-13 biosynthesis" EXACT [] +synonym: "negative regulation of IL-13 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-13 anabolism" EXACT [] +synonym: "negative regulation of interleukin-13 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-13 formation" EXACT [] +synonym: "negative regulation of interleukin-13 synthesis" EXACT [] +is_a: GO:0032696 ! negative regulation of interleukin-13 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045366 ! regulation of interleukin-13 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042231 ! interleukin-13 biosynthetic process +relationship: negatively_regulates GO:0042231 ! interleukin-13 biosynthetic process + +[Term] +id: GO:0045368 +name: positive regulation of interleukin-13 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] +synonym: "activation of interleukin-13 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-13 biosynthesis" EXACT [] +synonym: "positive regulation of IL-13 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-13 anabolism" EXACT [] +synonym: "positive regulation of interleukin-13 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-13 formation" EXACT [] +synonym: "positive regulation of interleukin-13 synthesis" EXACT [] +synonym: "stimulation of interleukin-13 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-13 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-13 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-13 biosynthetic process" EXACT [] +is_a: GO:0032736 ! positive regulation of interleukin-13 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045366 ! regulation of interleukin-13 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042231 ! interleukin-13 biosynthetic process +relationship: positively_regulates GO:0042231 ! interleukin-13 biosynthetic process + +[Term] +id: GO:0045369 +name: regulation of interleukin-14 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] +synonym: "regulation of IL-14 biosynthesis" EXACT [] +synonym: "regulation of IL-14 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-14 anabolism" EXACT [] +synonym: "regulation of interleukin-14 biosynthesis" EXACT [] +synonym: "regulation of interleukin-14 formation" EXACT [] +synonym: "regulation of interleukin-14 synthesis" EXACT [] +is_a: GO:0032657 ! regulation of interleukin-14 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042232 ! interleukin-14 biosynthetic process +relationship: regulates GO:0042232 ! interleukin-14 biosynthetic process + +[Term] +id: GO:0045370 +name: negative regulation of interleukin-14 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] +synonym: "down regulation of interleukin-14 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-14 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-14 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-14 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-14 biosynthesis" EXACT [] +synonym: "negative regulation of IL-14 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-14 anabolism" EXACT [] +synonym: "negative regulation of interleukin-14 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-14 formation" EXACT [] +synonym: "negative regulation of interleukin-14 synthesis" EXACT [] +is_a: GO:0032697 ! negative regulation of interleukin-14 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045369 ! regulation of interleukin-14 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042232 ! interleukin-14 biosynthetic process +relationship: negatively_regulates GO:0042232 ! interleukin-14 biosynthetic process + +[Term] +id: GO:0045371 +name: positive regulation of interleukin-14 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] +synonym: "activation of interleukin-14 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-14 biosynthesis" EXACT [] +synonym: "positive regulation of IL-14 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-14 anabolism" EXACT [] +synonym: "positive regulation of interleukin-14 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-14 formation" EXACT [] +synonym: "positive regulation of interleukin-14 synthesis" EXACT [] +synonym: "stimulation of interleukin-14 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-14 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-14 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-14 biosynthetic process" EXACT [] +is_a: GO:0032737 ! positive regulation of interleukin-14 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045369 ! regulation of interleukin-14 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042232 ! interleukin-14 biosynthetic process +relationship: positively_regulates GO:0042232 ! interleukin-14 biosynthetic process + +[Term] +id: GO:0045372 +name: regulation of interleukin-15 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] +synonym: "regulation of IL-15 biosynthesis" EXACT [] +synonym: "regulation of IL-15 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-15 anabolism" EXACT [] +synonym: "regulation of interleukin-15 biosynthesis" EXACT [] +synonym: "regulation of interleukin-15 formation" EXACT [] +synonym: "regulation of interleukin-15 synthesis" EXACT [] +is_a: GO:0032658 ! regulation of interleukin-15 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042233 ! interleukin-15 biosynthetic process +relationship: regulates GO:0042233 ! interleukin-15 biosynthetic process + +[Term] +id: GO:0045373 +name: negative regulation of interleukin-15 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] +synonym: "down regulation of interleukin-15 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-15 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-15 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-15 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-15 biosynthesis" EXACT [] +synonym: "negative regulation of IL-15 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-15 anabolism" EXACT [] +synonym: "negative regulation of interleukin-15 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-15 formation" EXACT [] +synonym: "negative regulation of interleukin-15 synthesis" EXACT [] +is_a: GO:0032698 ! negative regulation of interleukin-15 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045372 ! regulation of interleukin-15 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042233 ! interleukin-15 biosynthetic process +relationship: negatively_regulates GO:0042233 ! interleukin-15 biosynthetic process + +[Term] +id: GO:0045374 +name: positive regulation of interleukin-15 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] +synonym: "activation of interleukin-15 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-15 biosynthesis" EXACT [] +synonym: "positive regulation of IL-15 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-15 anabolism" EXACT [] +synonym: "positive regulation of interleukin-15 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-15 formation" EXACT [] +synonym: "positive regulation of interleukin-15 synthesis" EXACT [] +synonym: "stimulation of interleukin-15 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-15 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-15 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-15 biosynthetic process" EXACT [] +is_a: GO:0032738 ! positive regulation of interleukin-15 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045372 ! regulation of interleukin-15 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042233 ! interleukin-15 biosynthetic process +relationship: positively_regulates GO:0042233 ! interleukin-15 biosynthetic process + +[Term] +id: GO:0045375 +name: regulation of interleukin-16 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] +synonym: "regulation of IL-16 biosynthesis" EXACT [] +synonym: "regulation of IL-16 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-16 anabolism" EXACT [] +synonym: "regulation of interleukin-16 biosynthesis" EXACT [] +synonym: "regulation of interleukin-16 formation" EXACT [] +synonym: "regulation of interleukin-16 synthesis" EXACT [] +is_a: GO:0032659 ! regulation of interleukin-16 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042234 ! interleukin-16 biosynthetic process +relationship: regulates GO:0042234 ! interleukin-16 biosynthetic process + +[Term] +id: GO:0045376 +name: negative regulation of interleukin-16 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] +synonym: "down regulation of interleukin-16 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-16 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-16 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-16 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-16 biosynthesis" EXACT [] +synonym: "negative regulation of IL-16 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-16 anabolism" EXACT [] +synonym: "negative regulation of interleukin-16 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-16 formation" EXACT [] +synonym: "negative regulation of interleukin-16 synthesis" EXACT [] +is_a: GO:0032699 ! negative regulation of interleukin-16 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045375 ! regulation of interleukin-16 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042234 ! interleukin-16 biosynthetic process +relationship: negatively_regulates GO:0042234 ! interleukin-16 biosynthetic process + +[Term] +id: GO:0045377 +name: positive regulation of interleukin-16 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] +synonym: "activation of interleukin-16 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-16 biosynthesis" EXACT [] +synonym: "positive regulation of IL-16 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-16 anabolism" EXACT [] +synonym: "positive regulation of interleukin-16 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-16 formation" EXACT [] +synonym: "positive regulation of interleukin-16 synthesis" EXACT [] +synonym: "stimulation of interleukin-16 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-16 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-16 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-16 biosynthetic process" EXACT [] +is_a: GO:0032739 ! positive regulation of interleukin-16 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045375 ! regulation of interleukin-16 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042234 ! interleukin-16 biosynthetic process +relationship: positively_regulates GO:0042234 ! interleukin-16 biosynthetic process + +[Term] +id: GO:0045378 +name: regulation of interleukin-17 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:go_curators] +synonym: "regulation of IL-17 biosynthesis" EXACT [] +synonym: "regulation of IL-17 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-17 anabolism" EXACT [] +synonym: "regulation of interleukin-17 biosynthesis" EXACT [] +synonym: "regulation of interleukin-17 formation" EXACT [] +synonym: "regulation of interleukin-17 synthesis" EXACT [] +is_a: GO:0032660 ! regulation of interleukin-17 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042235 ! interleukin-17 biosynthetic process +relationship: regulates GO:0042235 ! interleukin-17 biosynthetic process + +[Term] +id: GO:0045379 +name: negative regulation of interleukin-17 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:go_curators] +synonym: "down regulation of interleukin-17 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-17 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-17 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-17 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-17 biosynthesis" EXACT [] +synonym: "negative regulation of IL-17 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-17 anabolism" EXACT [] +synonym: "negative regulation of interleukin-17 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-17 formation" EXACT [] +synonym: "negative regulation of interleukin-17 synthesis" EXACT [] +is_a: GO:0032700 ! negative regulation of interleukin-17 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045378 ! regulation of interleukin-17 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042235 ! interleukin-17 biosynthetic process +relationship: negatively_regulates GO:0042235 ! interleukin-17 biosynthetic process + +[Term] +id: GO:0045380 +name: positive regulation of interleukin-17 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines." [GOC:add, GOC:go_curators] +synonym: "activation of interleukin-17 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-17 biosynthesis" EXACT [] +synonym: "positive regulation of IL-17 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-17 anabolism" EXACT [] +synonym: "positive regulation of interleukin-17 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-17 formation" EXACT [] +synonym: "positive regulation of interleukin-17 synthesis" EXACT [] +synonym: "stimulation of interleukin-17 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-17 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-17 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-17 biosynthetic process" EXACT [] +is_a: GO:0032740 ! positive regulation of interleukin-17 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045378 ! regulation of interleukin-17 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042235 ! interleukin-17 biosynthetic process +relationship: positively_regulates GO:0042235 ! interleukin-17 biosynthetic process + +[Term] +id: GO:0045381 +name: regulation of interleukin-18 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] +synonym: "regulation of IL-18 biosynthesis" EXACT [] +synonym: "regulation of IL-18 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-18 anabolism" EXACT [] +synonym: "regulation of interleukin-18 biosynthesis" EXACT [] +synonym: "regulation of interleukin-18 formation" EXACT [] +synonym: "regulation of interleukin-18 synthesis" EXACT [] +is_a: GO:0032661 ! regulation of interleukin-18 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042241 ! interleukin-18 biosynthetic process +relationship: regulates GO:0042241 ! interleukin-18 biosynthetic process + +[Term] +id: GO:0045382 +name: negative regulation of interleukin-18 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] +synonym: "down regulation of interleukin-18 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-18 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-18 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-18 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-18 biosynthesis" EXACT [] +synonym: "negative regulation of IL-18 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-18 anabolism" EXACT [] +synonym: "negative regulation of interleukin-18 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-18 formation" EXACT [] +synonym: "negative regulation of interleukin-18 synthesis" EXACT [] +is_a: GO:0032701 ! negative regulation of interleukin-18 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045381 ! regulation of interleukin-18 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042241 ! interleukin-18 biosynthetic process +relationship: negatively_regulates GO:0042241 ! interleukin-18 biosynthetic process + +[Term] +id: GO:0045383 +name: positive regulation of interleukin-18 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] +synonym: "activation of interleukin-18 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-18 biosynthesis" EXACT [] +synonym: "positive regulation of IL-18 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-18 anabolism" EXACT [] +synonym: "positive regulation of interleukin-18 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-18 formation" EXACT [] +synonym: "positive regulation of interleukin-18 synthesis" EXACT [] +synonym: "stimulation of interleukin-18 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-18 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-18 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-18 biosynthetic process" EXACT [] +is_a: GO:0032741 ! positive regulation of interleukin-18 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045381 ! regulation of interleukin-18 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042241 ! interleukin-18 biosynthetic process +relationship: positively_regulates GO:0042241 ! interleukin-18 biosynthetic process + +[Term] +id: GO:0045384 +name: regulation of interleukin-19 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] +synonym: "regulation of IL-19 biosynthesis" EXACT [] +synonym: "regulation of IL-19 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-19 anabolism" EXACT [] +synonym: "regulation of interleukin-19 biosynthesis" EXACT [] +synonym: "regulation of interleukin-19 formation" EXACT [] +synonym: "regulation of interleukin-19 synthesis" EXACT [] +is_a: GO:0032662 ! regulation of interleukin-19 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042236 ! interleukin-19 biosynthetic process +relationship: regulates GO:0042236 ! interleukin-19 biosynthetic process + +[Term] +id: GO:0045385 +name: negative regulation of interleukin-19 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] +synonym: "down regulation of interleukin-19 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-19 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-19 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-19 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-19 biosynthesis" EXACT [] +synonym: "negative regulation of IL-19 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-19 anabolism" EXACT [] +synonym: "negative regulation of interleukin-19 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-19 formation" EXACT [] +synonym: "negative regulation of interleukin-19 synthesis" EXACT [] +is_a: GO:0032702 ! negative regulation of interleukin-19 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045384 ! regulation of interleukin-19 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042236 ! interleukin-19 biosynthetic process +relationship: negatively_regulates GO:0042236 ! interleukin-19 biosynthetic process + +[Term] +id: GO:0045386 +name: positive regulation of interleukin-19 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] +synonym: "activation of interleukin-19 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-19 biosynthesis" EXACT [] +synonym: "positive regulation of IL-19 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-19 anabolism" EXACT [] +synonym: "positive regulation of interleukin-19 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-19 formation" EXACT [] +synonym: "positive regulation of interleukin-19 synthesis" EXACT [] +synonym: "stimulation of interleukin-19 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-19 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-19 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-19 biosynthetic process" EXACT [] +is_a: GO:0032742 ! positive regulation of interleukin-19 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045384 ! regulation of interleukin-19 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042236 ! interleukin-19 biosynthetic process +relationship: positively_regulates GO:0042236 ! interleukin-19 biosynthetic process + +[Term] +id: GO:0045387 +name: regulation of interleukin-20 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] +synonym: "regulation of IL-20 biosynthesis" EXACT [] +synonym: "regulation of IL-20 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-20 anabolism" EXACT [] +synonym: "regulation of interleukin-20 biosynthesis" EXACT [] +synonym: "regulation of interleukin-20 formation" EXACT [] +synonym: "regulation of interleukin-20 synthesis" EXACT [] +is_a: GO:0032664 ! regulation of interleukin-20 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042237 ! interleukin-20 biosynthetic process +relationship: regulates GO:0042237 ! interleukin-20 biosynthetic process + +[Term] +id: GO:0045388 +name: negative regulation of interleukin-20 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] +synonym: "down regulation of interleukin-20 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-20 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-20 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-20 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-20 biosynthesis" EXACT [] +synonym: "negative regulation of IL-20 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-20 anabolism" EXACT [] +synonym: "negative regulation of interleukin-20 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-20 formation" EXACT [] +synonym: "negative regulation of interleukin-20 synthesis" EXACT [] +is_a: GO:0032704 ! negative regulation of interleukin-20 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045387 ! regulation of interleukin-20 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042237 ! interleukin-20 biosynthetic process +relationship: negatively_regulates GO:0042237 ! interleukin-20 biosynthetic process + +[Term] +id: GO:0045389 +name: positive regulation of interleukin-20 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] +synonym: "activation of interleukin-20 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-20 biosynthesis" EXACT [] +synonym: "positive regulation of IL-20 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-20 anabolism" EXACT [] +synonym: "positive regulation of interleukin-20 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-20 formation" EXACT [] +synonym: "positive regulation of interleukin-20 synthesis" EXACT [] +synonym: "stimulation of interleukin-20 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-20 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-20 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-20 biosynthetic process" EXACT [] +is_a: GO:0032744 ! positive regulation of interleukin-20 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045387 ! regulation of interleukin-20 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042237 ! interleukin-20 biosynthetic process +relationship: positively_regulates GO:0042237 ! interleukin-20 biosynthetic process + +[Term] +id: GO:0045390 +name: regulation of interleukin-21 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] +synonym: "regulation of IL-21 biosynthesis" EXACT [] +synonym: "regulation of IL-21 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-21 anabolism" EXACT [] +synonym: "regulation of interleukin-21 biosynthesis" EXACT [] +synonym: "regulation of interleukin-21 formation" EXACT [] +synonym: "regulation of interleukin-21 synthesis" EXACT [] +is_a: GO:0032665 ! regulation of interleukin-21 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042238 ! interleukin-21 biosynthetic process +relationship: regulates GO:0042238 ! interleukin-21 biosynthetic process + +[Term] +id: GO:0045391 +name: negative regulation of interleukin-21 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] +synonym: "down regulation of interleukin-21 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-21 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-21 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-21 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-21 biosynthesis" EXACT [] +synonym: "negative regulation of IL-21 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-21 anabolism" EXACT [] +synonym: "negative regulation of interleukin-21 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-21 formation" EXACT [] +synonym: "negative regulation of interleukin-21 synthesis" EXACT [] +is_a: GO:0032705 ! negative regulation of interleukin-21 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045390 ! regulation of interleukin-21 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042238 ! interleukin-21 biosynthetic process +relationship: negatively_regulates GO:0042238 ! interleukin-21 biosynthetic process + +[Term] +id: GO:0045392 +name: positive regulation of interleukin-21 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] +synonym: "activation of interleukin-21 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-21 biosynthesis" EXACT [] +synonym: "positive regulation of IL-21 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-21 anabolism" EXACT [] +synonym: "positive regulation of interleukin-21 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-21 formation" EXACT [] +synonym: "positive regulation of interleukin-21 synthesis" EXACT [] +synonym: "stimulation of interleukin-21 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-21 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-21 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-21 biosynthetic process" EXACT [] +is_a: GO:0032745 ! positive regulation of interleukin-21 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045390 ! regulation of interleukin-21 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042238 ! interleukin-21 biosynthetic process +relationship: positively_regulates GO:0042238 ! interleukin-21 biosynthetic process + +[Term] +id: GO:0045393 +name: regulation of interleukin-22 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] +synonym: "regulation of IL-22 biosynthesis" EXACT [] +synonym: "regulation of IL-22 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-22 anabolism" EXACT [] +synonym: "regulation of interleukin-22 biosynthesis" EXACT [] +synonym: "regulation of interleukin-22 formation" EXACT [] +synonym: "regulation of interleukin-22 synthesis" EXACT [] +is_a: GO:0032666 ! regulation of interleukin-22 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042239 ! interleukin-22 biosynthetic process +relationship: regulates GO:0042239 ! interleukin-22 biosynthetic process + +[Term] +id: GO:0045394 +name: negative regulation of interleukin-22 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] +synonym: "down regulation of interleukin-22 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-22 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-22 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-22 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-22 biosynthesis" EXACT [] +synonym: "negative regulation of IL-22 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-22 anabolism" EXACT [] +synonym: "negative regulation of interleukin-22 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-22 formation" EXACT [] +synonym: "negative regulation of interleukin-22 synthesis" EXACT [] +is_a: GO:0032706 ! negative regulation of interleukin-22 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045393 ! regulation of interleukin-22 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042239 ! interleukin-22 biosynthetic process +relationship: negatively_regulates GO:0042239 ! interleukin-22 biosynthetic process + +[Term] +id: GO:0045395 +name: positive regulation of interleukin-22 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] +synonym: "activation of interleukin-22 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-22 biosynthesis" EXACT [] +synonym: "positive regulation of IL-22 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-22 anabolism" EXACT [] +synonym: "positive regulation of interleukin-22 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-22 formation" EXACT [] +synonym: "positive regulation of interleukin-22 synthesis" EXACT [] +synonym: "stimulation of interleukin-22 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-22 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-22 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-22 biosynthetic process" EXACT [] +is_a: GO:0032746 ! positive regulation of interleukin-22 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045393 ! regulation of interleukin-22 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042239 ! interleukin-22 biosynthetic process +relationship: positively_regulates GO:0042239 ! interleukin-22 biosynthetic process + +[Term] +id: GO:0045396 +name: regulation of interleukin-23 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] +synonym: "regulation of IL-23 biosynthesis" EXACT [] +synonym: "regulation of IL-23 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-23 anabolism" EXACT [] +synonym: "regulation of interleukin-23 biosynthesis" EXACT [] +synonym: "regulation of interleukin-23 formation" EXACT [] +synonym: "regulation of interleukin-23 synthesis" EXACT [] +is_a: GO:0032667 ! regulation of interleukin-23 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042240 ! interleukin-23 biosynthetic process +relationship: regulates GO:0042240 ! interleukin-23 biosynthetic process + +[Term] +id: GO:0045397 +name: negative regulation of interleukin-23 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] +synonym: "down regulation of interleukin-23 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-23 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-23 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-23 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-23 biosynthesis" EXACT [] +synonym: "negative regulation of IL-23 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-23 anabolism" EXACT [] +synonym: "negative regulation of interleukin-23 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-23 formation" EXACT [] +synonym: "negative regulation of interleukin-23 synthesis" EXACT [] +is_a: GO:0032707 ! negative regulation of interleukin-23 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045396 ! regulation of interleukin-23 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042240 ! interleukin-23 biosynthetic process +relationship: negatively_regulates GO:0042240 ! interleukin-23 biosynthetic process + +[Term] +id: GO:0045398 +name: positive regulation of interleukin-23 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] +synonym: "activation of interleukin-23 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-23 biosynthesis" EXACT [] +synonym: "positive regulation of IL-23 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-23 anabolism" EXACT [] +synonym: "positive regulation of interleukin-23 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-23 formation" EXACT [] +synonym: "positive regulation of interleukin-23 synthesis" EXACT [] +synonym: "stimulation of interleukin-23 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-23 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-23 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-23 biosynthetic process" EXACT [] +is_a: GO:0032747 ! positive regulation of interleukin-23 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045396 ! regulation of interleukin-23 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042240 ! interleukin-23 biosynthetic process +relationship: positively_regulates GO:0042240 ! interleukin-23 biosynthetic process + +[Term] +id: GO:0045399 +name: regulation of interleukin-3 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] +synonym: "regulation of IL-3 biosynthesis" EXACT [] +synonym: "regulation of IL-3 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-3 anabolism" EXACT [] +synonym: "regulation of interleukin-3 biosynthesis" EXACT [] +synonym: "regulation of interleukin-3 formation" EXACT [] +synonym: "regulation of interleukin-3 synthesis" EXACT [] +is_a: GO:0032672 ! regulation of interleukin-3 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042223 ! interleukin-3 biosynthetic process +relationship: regulates GO:0042223 ! interleukin-3 biosynthetic process + +[Term] +id: GO:0045400 +name: negative regulation of interleukin-3 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] +synonym: "down regulation of interleukin-3 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-3 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-3 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-3 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-3 biosynthesis" EXACT [] +synonym: "negative regulation of IL-3 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-3 anabolism" EXACT [] +synonym: "negative regulation of interleukin-3 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-3 formation" EXACT [] +synonym: "negative regulation of interleukin-3 synthesis" EXACT [] +is_a: GO:0032712 ! negative regulation of interleukin-3 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045399 ! regulation of interleukin-3 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042223 ! interleukin-3 biosynthetic process +relationship: negatively_regulates GO:0042223 ! interleukin-3 biosynthetic process + +[Term] +id: GO:0045401 +name: positive regulation of interleukin-3 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] +synonym: "activation of interleukin-3 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-3 biosynthesis" EXACT [] +synonym: "positive regulation of IL-3 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-3 anabolism" EXACT [] +synonym: "positive regulation of interleukin-3 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-3 formation" EXACT [] +synonym: "positive regulation of interleukin-3 synthesis" EXACT [] +synonym: "stimulation of interleukin-3 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-3 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-3 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-3 biosynthetic process" EXACT [] +is_a: GO:0032752 ! positive regulation of interleukin-3 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045399 ! regulation of interleukin-3 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042223 ! interleukin-3 biosynthetic process +relationship: positively_regulates GO:0042223 ! interleukin-3 biosynthetic process + +[Term] +id: GO:0045402 +name: regulation of interleukin-4 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] +synonym: "regulation of IL-4 biosynthesis" EXACT [] +synonym: "regulation of IL-4 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-4 anabolism" EXACT [] +synonym: "regulation of interleukin-4 biosynthesis" EXACT [] +synonym: "regulation of interleukin-4 formation" EXACT [] +synonym: "regulation of interleukin-4 synthesis" EXACT [] +is_a: GO:0032673 ! regulation of interleukin-4 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042097 ! interleukin-4 biosynthetic process +relationship: regulates GO:0042097 ! interleukin-4 biosynthetic process + +[Term] +id: GO:0045403 +name: negative regulation of interleukin-4 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] +synonym: "down regulation of interleukin-4 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-4 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-4 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-4 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-4 biosynthesis" EXACT [] +synonym: "negative regulation of IL-4 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-4 anabolism" EXACT [] +synonym: "negative regulation of interleukin-4 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-4 formation" EXACT [] +synonym: "negative regulation of interleukin-4 synthesis" EXACT [] +is_a: GO:0032713 ! negative regulation of interleukin-4 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045402 ! regulation of interleukin-4 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042097 ! interleukin-4 biosynthetic process +relationship: negatively_regulates GO:0042097 ! interleukin-4 biosynthetic process + +[Term] +id: GO:0045404 +name: positive regulation of interleukin-4 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] +synonym: "activation of interleukin-4 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-4 biosynthesis" EXACT [] +synonym: "positive regulation of IL-4 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-4 anabolism" EXACT [] +synonym: "positive regulation of interleukin-4 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-4 formation" EXACT [] +synonym: "positive regulation of interleukin-4 synthesis" EXACT [] +synonym: "stimulation of interleukin-4 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-4 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-4 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-4 biosynthetic process" EXACT [] +is_a: GO:0032753 ! positive regulation of interleukin-4 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045402 ! regulation of interleukin-4 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042097 ! interleukin-4 biosynthetic process +relationship: positively_regulates GO:0042097 ! interleukin-4 biosynthetic process + +[Term] +id: GO:0045405 +name: regulation of interleukin-5 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] +synonym: "regulation of IL-5 biosynthesis" EXACT [] +synonym: "regulation of IL-5 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-5 anabolism" EXACT [] +synonym: "regulation of interleukin-5 biosynthesis" EXACT [] +synonym: "regulation of interleukin-5 formation" EXACT [] +synonym: "regulation of interleukin-5 synthesis" EXACT [] +is_a: GO:0032674 ! regulation of interleukin-5 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042225 ! interleukin-5 biosynthetic process +relationship: regulates GO:0042225 ! interleukin-5 biosynthetic process + +[Term] +id: GO:0045406 +name: negative regulation of interleukin-5 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] +synonym: "down regulation of interleukin-5 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-5 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-5 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-5 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-5 biosynthesis" EXACT [] +synonym: "negative regulation of IL-5 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-5 anabolism" EXACT [] +synonym: "negative regulation of interleukin-5 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-5 formation" EXACT [] +synonym: "negative regulation of interleukin-5 synthesis" EXACT [] +is_a: GO:0032714 ! negative regulation of interleukin-5 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045405 ! regulation of interleukin-5 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042225 ! interleukin-5 biosynthetic process +relationship: negatively_regulates GO:0042225 ! interleukin-5 biosynthetic process + +[Term] +id: GO:0045407 +name: positive regulation of interleukin-5 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] +synonym: "activation of interleukin-5 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-5 biosynthesis" EXACT [] +synonym: "positive regulation of IL-5 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-5 anabolism" EXACT [] +synonym: "positive regulation of interleukin-5 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-5 formation" EXACT [] +synonym: "positive regulation of interleukin-5 synthesis" EXACT [] +synonym: "stimulation of interleukin-5 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-5 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-5 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-5 biosynthetic process" EXACT [] +is_a: GO:0032754 ! positive regulation of interleukin-5 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045405 ! regulation of interleukin-5 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042225 ! interleukin-5 biosynthetic process +relationship: positively_regulates GO:0042225 ! interleukin-5 biosynthetic process + +[Term] +id: GO:0045408 +name: regulation of interleukin-6 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] +synonym: "regulation of IL-6 biosynthesis" EXACT [] +synonym: "regulation of IL-6 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-6 anabolism" EXACT [] +synonym: "regulation of interleukin-6 biosynthesis" EXACT [] +synonym: "regulation of interleukin-6 formation" EXACT [] +synonym: "regulation of interleukin-6 synthesis" EXACT [] +is_a: GO:0032675 ! regulation of interleukin-6 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042226 ! interleukin-6 biosynthetic process +relationship: regulates GO:0042226 ! interleukin-6 biosynthetic process + +[Term] +id: GO:0045409 +name: negative regulation of interleukin-6 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] +synonym: "down regulation of interleukin-6 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-6 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-6 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-6 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-6 biosynthesis" EXACT [] +synonym: "negative regulation of IL-6 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-6 anabolism" EXACT [] +synonym: "negative regulation of interleukin-6 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-6 formation" EXACT [] +synonym: "negative regulation of interleukin-6 synthesis" EXACT [] +is_a: GO:0032715 ! negative regulation of interleukin-6 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045408 ! regulation of interleukin-6 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042226 ! interleukin-6 biosynthetic process +relationship: negatively_regulates GO:0042226 ! interleukin-6 biosynthetic process + +[Term] +id: GO:0045410 +name: positive regulation of interleukin-6 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] +synonym: "activation of interleukin-6 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-6 biosynthesis" EXACT [] +synonym: "positive regulation of IL-6 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-6 anabolism" EXACT [] +synonym: "positive regulation of interleukin-6 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-6 formation" EXACT [] +synonym: "positive regulation of interleukin-6 synthesis" EXACT [] +synonym: "stimulation of interleukin-6 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-6 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-6 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-6 biosynthetic process" EXACT [] +is_a: GO:0032755 ! positive regulation of interleukin-6 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045408 ! regulation of interleukin-6 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042226 ! interleukin-6 biosynthetic process +relationship: positively_regulates GO:0042226 ! interleukin-6 biosynthetic process + +[Term] +id: GO:0045411 +name: regulation of interleukin-7 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] +synonym: "regulation of IL-7 biosynthesis" EXACT [] +synonym: "regulation of IL-7 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-7 anabolism" EXACT [] +synonym: "regulation of interleukin-7 biosynthesis" EXACT [] +synonym: "regulation of interleukin-7 formation" EXACT [] +synonym: "regulation of interleukin-7 synthesis" EXACT [] +is_a: GO:0032676 ! regulation of interleukin-7 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042227 ! interleukin-7 biosynthetic process +relationship: regulates GO:0042227 ! interleukin-7 biosynthetic process + +[Term] +id: GO:0045412 +name: negative regulation of interleukin-7 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] +synonym: "down regulation of interleukin-7 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-7 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-7 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-7 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-7 biosynthesis" EXACT [] +synonym: "negative regulation of IL-7 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-7 anabolism" EXACT [] +synonym: "negative regulation of interleukin-7 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-7 formation" EXACT [] +synonym: "negative regulation of interleukin-7 synthesis" EXACT [] +is_a: GO:0032716 ! negative regulation of interleukin-7 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045411 ! regulation of interleukin-7 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042227 ! interleukin-7 biosynthetic process +relationship: negatively_regulates GO:0042227 ! interleukin-7 biosynthetic process + +[Term] +id: GO:0045413 +name: positive regulation of interleukin-7 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] +synonym: "activation of interleukin-7 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-7 biosynthesis" EXACT [] +synonym: "positive regulation of IL-7 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-7 anabolism" EXACT [] +synonym: "positive regulation of interleukin-7 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-7 formation" EXACT [] +synonym: "positive regulation of interleukin-7 synthesis" EXACT [] +synonym: "stimulation of interleukin-7 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-7 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-7 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-7 biosynthetic process" EXACT [] +is_a: GO:0032756 ! positive regulation of interleukin-7 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045411 ! regulation of interleukin-7 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042227 ! interleukin-7 biosynthetic process +relationship: positively_regulates GO:0042227 ! interleukin-7 biosynthetic process + +[Term] +id: GO:0045414 +name: regulation of interleukin-8 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] +synonym: "regulation of IL-8 biosynthesis" EXACT [] +synonym: "regulation of IL-8 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-8 anabolism" EXACT [] +synonym: "regulation of interleukin-8 biosynthesis" EXACT [] +synonym: "regulation of interleukin-8 formation" EXACT [] +synonym: "regulation of interleukin-8 synthesis" EXACT [] +is_a: GO:0032677 ! regulation of interleukin-8 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042228 ! interleukin-8 biosynthetic process +relationship: regulates GO:0042228 ! interleukin-8 biosynthetic process + +[Term] +id: GO:0045415 +name: negative regulation of interleukin-8 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] +synonym: "down regulation of interleukin-8 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-8 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-8 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-8 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-8 biosynthesis" EXACT [] +synonym: "negative regulation of IL-8 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-8 anabolism" EXACT [] +synonym: "negative regulation of interleukin-8 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-8 formation" EXACT [] +synonym: "negative regulation of interleukin-8 synthesis" EXACT [] +is_a: GO:0032717 ! negative regulation of interleukin-8 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045414 ! regulation of interleukin-8 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042228 ! interleukin-8 biosynthetic process +relationship: negatively_regulates GO:0042228 ! interleukin-8 biosynthetic process + +[Term] +id: GO:0045416 +name: positive regulation of interleukin-8 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] +synonym: "activation of interleukin-8 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-8 biosynthesis" EXACT [] +synonym: "positive regulation of IL-8 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-8 anabolism" EXACT [] +synonym: "positive regulation of interleukin-8 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-8 formation" EXACT [] +synonym: "positive regulation of interleukin-8 synthesis" EXACT [] +synonym: "stimulation of interleukin-8 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-8 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-8 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-8 biosynthetic process" EXACT [] +is_a: GO:0032757 ! positive regulation of interleukin-8 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045414 ! regulation of interleukin-8 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042228 ! interleukin-8 biosynthetic process +relationship: positively_regulates GO:0042228 ! interleukin-8 biosynthetic process + +[Term] +id: GO:0045417 +name: regulation of interleukin-9 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] +synonym: "regulation of IL-9 biosynthesis" EXACT [] +synonym: "regulation of IL-9 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-9 anabolism" EXACT [] +synonym: "regulation of interleukin-9 biosynthesis" EXACT [] +synonym: "regulation of interleukin-9 formation" EXACT [] +synonym: "regulation of interleukin-9 synthesis" EXACT [] +is_a: GO:0032678 ! regulation of interleukin-9 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042229 ! interleukin-9 biosynthetic process +relationship: regulates GO:0042229 ! interleukin-9 biosynthetic process + +[Term] +id: GO:0045418 +name: negative regulation of interleukin-9 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] +synonym: "down regulation of interleukin-9 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-9 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-9 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-9 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-9 biosynthesis" EXACT [] +synonym: "negative regulation of IL-9 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-9 anabolism" EXACT [] +synonym: "negative regulation of interleukin-9 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-9 formation" EXACT [] +synonym: "negative regulation of interleukin-9 synthesis" EXACT [] +is_a: GO:0032718 ! negative regulation of interleukin-9 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045417 ! regulation of interleukin-9 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042229 ! interleukin-9 biosynthetic process +relationship: negatively_regulates GO:0042229 ! interleukin-9 biosynthetic process + +[Term] +id: GO:0045419 +name: positive regulation of interleukin-9 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] +synonym: "activation of interleukin-9 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-9 biosynthesis" EXACT [] +synonym: "positive regulation of IL-9 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-9 anabolism" EXACT [] +synonym: "positive regulation of interleukin-9 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-9 formation" EXACT [] +synonym: "positive regulation of interleukin-9 synthesis" EXACT [] +synonym: "stimulation of interleukin-9 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-9 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-9 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-9 biosynthetic process" EXACT [] +is_a: GO:0032758 ! positive regulation of interleukin-9 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045417 ! regulation of interleukin-9 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042229 ! interleukin-9 biosynthetic process +relationship: positively_regulates GO:0042229 ! interleukin-9 biosynthetic process + +[Term] +id: GO:0045420 +name: regulation of connective tissue growth factor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] +synonym: "regulation of connective tissue growth factor anabolism" EXACT [] +synonym: "regulation of connective tissue growth factor biosynthesis" EXACT [] +synonym: "regulation of connective tissue growth factor formation" EXACT [] +synonym: "regulation of connective tissue growth factor synthesis" EXACT [] +is_a: GO:0032643 ! regulation of connective tissue growth factor production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045189 ! connective tissue growth factor biosynthetic process +relationship: regulates GO:0045189 ! connective tissue growth factor biosynthetic process + +[Term] +id: GO:0045421 +name: negative regulation of connective tissue growth factor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] +synonym: "down regulation of connective tissue growth factor biosynthetic process" EXACT [] +synonym: "down-regulation of connective tissue growth factor biosynthetic process" EXACT [] +synonym: "downregulation of connective tissue growth factor biosynthetic process" EXACT [] +synonym: "inhibition of connective tissue growth factor biosynthetic process" NARROW [] +synonym: "negative regulation of connective tissue growth factor anabolism" EXACT [] +synonym: "negative regulation of connective tissue growth factor biosynthesis" EXACT [] +synonym: "negative regulation of connective tissue growth factor formation" EXACT [] +synonym: "negative regulation of connective tissue growth factor synthesis" EXACT [] +is_a: GO:0032683 ! negative regulation of connective tissue growth factor production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045420 ! regulation of connective tissue growth factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045189 ! connective tissue growth factor biosynthetic process +relationship: negatively_regulates GO:0045189 ! connective tissue growth factor biosynthetic process + +[Term] +id: GO:0045422 +name: positive regulation of connective tissue growth factor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] +synonym: "activation of connective tissue growth factor biosynthetic process" NARROW [] +synonym: "positive regulation of connective tissue growth factor anabolism" EXACT [] +synonym: "positive regulation of connective tissue growth factor biosynthesis" EXACT [] +synonym: "positive regulation of connective tissue growth factor formation" EXACT [] +synonym: "positive regulation of connective tissue growth factor synthesis" EXACT [] +synonym: "stimulation of connective tissue growth factor biosynthetic process" NARROW [] +synonym: "up regulation of connective tissue growth factor biosynthetic process" EXACT [] +synonym: "up-regulation of connective tissue growth factor biosynthetic process" EXACT [] +synonym: "upregulation of connective tissue growth factor biosynthetic process" EXACT [] +is_a: GO:0032723 ! positive regulation of connective tissue growth factor production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045420 ! regulation of connective tissue growth factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045189 ! connective tissue growth factor biosynthetic process +relationship: positively_regulates GO:0045189 ! connective tissue growth factor biosynthetic process + +[Term] +id: GO:0045423 +name: regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] +synonym: "regulation of GM-CSF biosynthesis" EXACT [GOC:vk] +synonym: "regulation of granulocyte macrophage colony stimulating factor biosynthetic process" EXACT [] +synonym: "regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] +synonym: "regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] +synonym: "regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] +synonym: "regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] +is_a: GO:0032645 ! regulation of granulocyte macrophage colony-stimulating factor production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process +relationship: regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process + +[Term] +id: GO:0045424 +name: negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] +synonym: "down regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +synonym: "down-regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +synonym: "downregulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +synonym: "inhibition of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] +synonym: "negative regulation of GM-CSF biosynthesis" EXACT [GOC:vk] +synonym: "negative regulation of granulocyte macrophage colony stimulating factor biosynthetic process" EXACT [] +synonym: "negative regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] +synonym: "negative regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] +synonym: "negative regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] +synonym: "negative regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] +is_a: GO:0032685 ! negative regulation of granulocyte macrophage colony-stimulating factor production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045423 ! regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process +relationship: negatively_regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process + +[Term] +id: GO:0045425 +name: positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] +synonym: "activation of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] +synonym: "positive regulation of GM-CSF biosynthesis" RELATED [GOC:vk] +synonym: "positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process" EXACT [] +synonym: "positive regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] +synonym: "positive regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] +synonym: "positive regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] +synonym: "positive regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] +synonym: "stimulation of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] +synonym: "up regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +synonym: "up-regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +synonym: "upregulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] +is_a: GO:0032725 ! positive regulation of granulocyte macrophage colony-stimulating factor production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045423 ! regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process +relationship: positively_regulates GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process + +[Term] +id: GO:0045427 +name: enzyme active site formation via (phospho-5'-guanosine)-L-histidine +namespace: biological_process +def: "The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine." [RESID:AA0325] +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0098825 ! peptidyl-histidine guanylation + +[Term] +id: GO:0045428 +name: regulation of nitric oxide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] +synonym: "regulation of nitric oxide anabolism" EXACT [] +synonym: "regulation of nitric oxide biosynthesis" EXACT [] +synonym: "regulation of nitric oxide formation" EXACT [] +synonym: "regulation of nitric oxide synthesis" EXACT [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006809 ! nitric oxide biosynthetic process +relationship: regulates GO:0006809 ! nitric oxide biosynthetic process + +[Term] +id: GO:0045429 +name: positive regulation of nitric oxide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] +synonym: "activation of nitric oxide biosynthetic process" NARROW [] +synonym: "positive regulation of nitric oxide anabolism" EXACT [] +synonym: "positive regulation of nitric oxide biosynthesis" EXACT [] +synonym: "positive regulation of nitric oxide formation" EXACT [] +synonym: "positive regulation of nitric oxide synthesis" EXACT [] +synonym: "stimulation of nitric oxide biosynthetic process" NARROW [] +synonym: "up regulation of nitric oxide biosynthetic process" EXACT [] +synonym: "up-regulation of nitric oxide biosynthetic process" EXACT [] +synonym: "upregulation of nitric oxide biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process +is_a: GO:1903428 ! positive regulation of reactive oxygen species biosynthetic process +is_a: GO:1904407 ! positive regulation of nitric oxide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006809 ! nitric oxide biosynthetic process +relationship: positively_regulates GO:0006809 ! nitric oxide biosynthetic process + +[Term] +id: GO:0045430 +name: chalcone isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: a chalcone = a flavanone." [EC:5.5.1.6] +synonym: "chalcone--flavonone isomerase activity" EXACT [EC:5.5.1.6] +synonym: "chalcone-flavanone isomerase activity" EXACT [] +synonym: "flavanone lyase (decyclizing)" EXACT [EC:5.5.1.6] +xref: EC:5.5.1.6 +xref: MetaCyc:CHALCONE-ISOMERASE-RXN +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0045431 +name: flavonol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O." [EC:1.14.20.6, ISBN:0943088372, PMID:7904213] +synonym: "dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.20.6] +synonym: "flavonoid 2-oxoglutarate-dependent dioxygenase activity" EXACT [EC:1.14.20.6] +synonym: "FLS activity" RELATED [EC:1.14.20.6] +xref: EC:1.14.20.6 +xref: RHEA:21088 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +relationship: part_of GO:0051555 ! flavonol biosynthetic process + +[Term] +id: GO:0045433 +name: male courtship behavior, veined wing generated song production +namespace: biological_process +def: "The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song." [GOC:mtg_sensu, PMID:11092827] +synonym: "male courtship behavior, song production" BROAD [] +synonym: "male courtship behaviour, song production" BROAD [] +synonym: "male courtship behaviour, veined wing generated song production" EXACT [] +is_a: GO:0008049 ! male courtship behavior +relationship: part_of GO:0016545 ! male courtship behavior, veined wing vibration + +[Term] +id: GO:0045434 +name: negative regulation of female receptivity, post-mating +namespace: biological_process +def: "Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating." [GOC:bf, PMID:11092827] +synonym: "down regulation of female receptivity, post-mating" EXACT [] +synonym: "down-regulation of female receptivity, post-mating" EXACT [] +synonym: "downregulation of female receptivity, post-mating" EXACT [] +synonym: "inhibition of female receptivity, post-mating" NARROW [] +is_a: GO:0007621 ! negative regulation of female receptivity +is_a: GO:0046008 ! regulation of female receptivity, post-mating + +[Term] +id: GO:0045435 +name: lycopene epsilon cyclase activity +namespace: molecular_function +def: "Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene)." [PMID:8837512] +synonym: "lycopene cyclase" BROAD [] +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0045436 +name: lycopene beta cyclase activity +namespace: molecular_function +def: "Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively." [PMID:8837512] +synonym: "crtL" RELATED [] +synonym: "lycopene cyclase" BROAD [] +xref: MetaCyc:RXN1F-150 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0045437 +name: uridine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil." [EC:3.2.2.3, RHEA:15577] +synonym: "uridine hydrolase activity" EXACT [] +synonym: "uridine ribohydrolase activity" EXACT [EC:3.2.2.3] +xref: EC:3.2.2.3 +xref: KEGG_REACTION:R01080 +xref: MetaCyc:URIDINE-NUCLEOSIDASE-RXN +xref: RHEA:15577 +is_a: GO:0050263 ! ribosylpyrimidine nucleosidase activity + +[Term] +id: GO:0045438 +name: delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity +namespace: molecular_function +def: "Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol." [PMID:1572368, PMID:2061333] +synonym: "ACV synthetase activity" BROAD [] +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0045439 +name: isopenicillin-N epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: isopenicillin N = penicillin N." [EC:5.1.1.17, RHEA:20033] +synonym: "isopenicillin N epimerase activity" EXACT [] +synonym: "penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity" EXACT [EC:5.1.1.17] +xref: EC:5.1.1.17 +xref: KEGG_REACTION:R04147 +xref: MetaCyc:5.1.1.17-RXN +xref: RHEA:20033 +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives + +[Term] +id: GO:0045442 +name: deacetoxycephalosporin-C hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate." [EC:1.14.11.26, RHEA:16805] +synonym: "3'-methylcephem hydroxylase activity" EXACT [EC:1.14.11.26] +synonym: "beta-lactam hydroxylase activity" EXACT [] +synonym: "DACS" RELATED [EC:1.14.11.26] +synonym: "DAOC hydroxylase activity" EXACT [EC:1.14.11.26] +synonym: "deacetoxycephalosporin C hydroxylase activity" EXACT [EC:1.14.11.26] +synonym: "deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.26] +synonym: "deacetylcephalosporin C synthase activity" EXACT [EC:1.14.11.26] +xref: EC:1.14.11.26 +xref: KEGG_REACTION:R05229 +xref: MetaCyc:1.14.11.26-RXN +xref: RHEA:16805 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0045443 +name: juvenile hormone secretion +namespace: biological_process +def: "The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:go_curators, ISBN:0198547684] +is_a: GO:0046865 ! terpenoid transport +is_a: GO:0060986 ! endocrine hormone secretion +is_a: GO:0140353 ! lipid export from cell + +[Term] +id: GO:0045444 +name: fat cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators] +synonym: "adipocyte cell differentiation" EXACT [] +synonym: "adipocyte differentiation" EXACT [] +synonym: "adipogenesis" RELATED [] +synonym: "adipose cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0045445 +name: myoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] +synonym: "myoblast cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0061061 ! muscle structure development + +[Term] +id: GO:0045446 +name: endothelial cell differentiation +namespace: biological_process +def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0003158 ! endothelium development + +[Term] +id: GO:0045448 +name: mitotic cell cycle, embryonic +namespace: biological_process +def: "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo." [GOC:go_curators] +is_a: GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0045450 +name: bicoid mRNA localization +namespace: biological_process +def: "Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis." [GOC:go_curators] +synonym: "bicoid mRNA localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of bicoid mRNA localization" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0060811 ! intracellular mRNA localization involved in anterior/posterior axis specification +relationship: part_of GO:0007314 ! oocyte anterior/posterior axis specification + +[Term] +id: GO:0045451 +name: pole plasm oskar mRNA localization +namespace: biological_process +def: "Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm." [GOC:go_curators] +synonym: "establishment and maintenance of oskar mRNA localization in pole plasm" EXACT [] +synonym: "establishment and maintenance of pole plasm oskar mRNA localization" EXACT [] +synonym: "oocyte pole plasm oskar mRNA localization" EXACT [] +synonym: "pole plasm oskar mRNA localisation" EXACT [GOC:mah] +is_a: GO:0019094 ! pole plasm mRNA localization + +[Term] +id: GO:0045453 +name: bone resorption +namespace: biological_process +def: "The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products." [GOC:mah, PMID:10968780] +xref: Wikipedia:Bone_resorption +is_a: GO:0001894 ! tissue homeostasis +relationship: part_of GO:0046849 ! bone remodeling + +[Term] +id: GO:0045454 +name: cell redox homeostasis +namespace: biological_process +alt_id: GO:0030503 +alt_id: GO:0045867 +alt_id: GO:0045868 +def: "Any process that maintains the redox environment of a cell or compartment within a cell." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_drosophila +subset: goslim_metagenomics +synonym: "regulation of cell redox homeostasis" RELATED [] +synonym: "regulation of redox homeostasis" BROAD [] +is_a: GO:0019725 ! cellular homeostasis +is_a: GO:0050794 ! regulation of cellular process + +[Term] +id: GO:0045455 +name: ecdysteroid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732] +synonym: "ecdysteroid metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0034754 ! cellular hormone metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +relationship: part_of GO:0002165 ! instar larval or pupal development + +[Term] +id: GO:0045456 +name: ecdysteroid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development." [GOC:go_curators] +synonym: "ecdysteroid anabolism" EXACT [] +synonym: "ecdysteroid biosynthesis" EXACT [] +synonym: "ecdysteroid formation" EXACT [] +synonym: "ecdysteroid synthesis" EXACT [] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0045455 ! ecdysteroid metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process + +[Term] +id: GO:0045457 +name: ecdysteroid secretion +namespace: biological_process +def: "The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development." [GOC:go_curators] +is_a: GO:0035929 ! steroid hormone secretion + +[Term] +id: GO:0045458 +name: recombination within rDNA repeats +namespace: biological_process +def: "Genetic recombination within the DNA of the genes coding for ribosomal RNA." [GOC:go_curators, ISBN:0198506732] +comment: Note that this term was reinstated from obsolete. +synonym: "recombination within ribosomal DNA repeats" EXACT [] +is_a: GO:0006310 ! DNA recombination +is_a: GO:0043007 ! maintenance of rDNA + +[Term] +id: GO:0045459 +name: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide." [PMID:11592901, RESID:AA0326] +synonym: "iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide" EXACT [] +xref: RESID:AA0326 +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0045460 +name: sterigmatocystin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds." [PMID:10618248] +synonym: "sterigmatocystin metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process + +[Term] +id: GO:0045461 +name: sterigmatocystin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds." [PMID:10618248] +synonym: "sterigmatocystin anabolism" EXACT [] +synonym: "sterigmatocystin biosynthesis" EXACT [] +synonym: "sterigmatocystin formation" EXACT [] +synonym: "sterigmatocystin synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0045460 ! sterigmatocystin metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process + +[Term] +id: GO:0045462 +name: trichothecene 3-O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis." [PMID:10583973] +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0045463 +name: R8 cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium." [PMID:11880339] +is_a: GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0045465 ! R8 cell differentiation + +[Term] +id: GO:0045464 +name: R8 cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [PMID:11880339] +is_a: GO:0043704 ! photoreceptor cell fate specification +relationship: part_of GO:0007460 ! R8 cell fate commitment + +[Term] +id: GO:0045465 +name: R8 cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor." [PMID:11880339] +is_a: GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0045466 +name: R7 cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor." [PMID:11880339] +is_a: GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0045467 +name: R7 cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium." [PMID:11880339] +is_a: GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0045466 ! R7 cell differentiation + +[Term] +id: GO:0045468 +name: regulation of R8 cell spacing in compound eye +namespace: biological_process +def: "Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc." [GOC:dph, GOC:tb, PMID:11880339] +synonym: "R8 cell spacing in compound eye" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of R8 spacing" EXACT [GOC:dph] +is_a: GO:0007389 ! pattern specification process +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0048749 ! compound eye development + +[Term] +id: GO:0045469 +name: negative regulation of R8 cell spacing in compound eye +namespace: biological_process +def: "Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye." [GOC:dph, GOC:tb, PMID:11880339] +synonym: "down regulation of R8 spacing" EXACT [] +synonym: "down-regulation of R8 spacing" EXACT [] +synonym: "downregulation of R8 spacing" EXACT [] +synonym: "inhibition of R8 spacing" NARROW [] +is_a: GO:0045468 ! regulation of R8 cell spacing in compound eye + +[Term] +id: GO:0045470 +name: R8 cell-mediated photoreceptor organization +namespace: biological_process +def: "The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor." [PMID:11880339] +synonym: "R8-mediated photoreceptor organisation" EXACT [] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0042051 ! compound eye photoreceptor development + +[Term] +id: GO:0045471 +name: response to ethanol +namespace: biological_process +alt_id: GO:0017036 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus." [GOC:go_curators] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol + +[Term] +id: GO:0045472 +name: response to ether +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus." [GOC:go_curators] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0045473 +name: obsolete response to ethanol (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus." [GOC:go_curators, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "response to ethanol (sensu Insecta)" EXACT [] +is_obsolete: true +consider: GO:0048149 + +[Term] +id: GO:0045474 +name: obsolete response to ether (sensu Insecta) +namespace: biological_process +def: "OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ether stimulus." [GOC:go_curators, GOC:jid] +comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. +synonym: "response to ether (sensu Insecta)" EXACT [] +is_obsolete: true +consider: GO:0048150 + +[Term] +id: GO:0045475 +name: locomotor rhythm +namespace: biological_process +def: "The rhythm of the locomotor activity of an organism during its 24 hour activity cycle." [GOC:go_curators] +synonym: "circadian locomotor activity rhythm" NARROW [] +is_a: GO:0007626 ! locomotory behavior +is_a: GO:0048512 ! circadian behavior + +[Term] +id: GO:0045476 +name: nurse cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process." [CL:0000026, GOC:mtg_apoptosis, PMID:11973306] +synonym: "apoptosis of nurse cells" EXACT [] +synonym: "invertebrate nurse cell apoptosis" NARROW [] +synonym: "nurse cell apoptosis" NARROW [] +synonym: "nurse cell programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of nurse cells by apoptosis" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010623 ! programmed cell death involved in cell development +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:1902742 ! apoptotic process involved in development +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0045477 +name: regulation of nurse cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nurse cell apoptotic process." [GOC:mtg_apoptosis, PMID:11973306] +synonym: "regulation of nurse cell apoptosis" NARROW [] +is_a: GO:1904748 ! regulation of apoptotic process involved in development +is_a: GO:1905879 ! regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045476 ! nurse cell apoptotic process +relationship: regulates GO:0045476 ! nurse cell apoptotic process + +[Term] +id: GO:0045478 +name: fusome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells." [GOC:dph, GOC:go_curators, GOC:jl, GOC:mah] +subset: goslim_pir +synonym: "fusome organisation" EXACT [] +synonym: "fusome organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism + +[Term] +id: GO:0045479 +name: vesicle targeting to fusome +namespace: biological_process +def: "The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome." [PMID:9046244] +synonym: "vesicle-fusome targeting" EXACT [] +is_a: GO:0006903 ! vesicle targeting +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0045478 ! fusome organization + +[Term] +id: GO:0045480 +name: galactose oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide." [EC:1.1.3.9] +synonym: "beta-galactose oxidase activity" RELATED [EC:1.1.3.9] +synonym: "D-galactose oxidase activity" EXACT [EC:1.1.3.9] +synonym: "D-galactose:oxygen 6-oxidoreductase activity" EXACT [EC:1.1.3.9] +xref: EC:1.1.3.9 +xref: MetaCyc:GALACTOSE-OXIDASE-RXN +xref: RHEA:24160 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0045481 +name: 6-endo-hydroxycineole dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH." [EC:1.1.1.241, RHEA:11736] +synonym: "6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.241] +xref: EC:1.1.1.241 +xref: KEGG_REACTION:R02994 +xref: MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN +xref: RHEA:11736 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0045482 +name: trichodiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene." [EC:4.2.3.6, RHEA:12052] +synonym: "sesquiterpene cyclase activity" BROAD [EC:4.2.3.6] +synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)" EXACT [EC:4.2.3.6] +synonym: "trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity" EXACT [EC:4.2.3.6] +synonym: "trichodiene synthetase activity" EXACT [EC:4.2.3.6] +xref: EC:4.2.3.6 +xref: KEGG_REACTION:R02306 +xref: MetaCyc:TRICHODIENE-SYNTHASE-RXN +xref: RHEA:12052 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0045483 +name: aristolochene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate." [EC:4.2.3.9] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)" EXACT [EC:4.2.3.9] +synonym: "sesquiterpene cyclase activity" BROAD [EC:4.2.3.9] +synonym: "trans,trans-farnesyl diphosphate aristolochene-lyase activity" EXACT [EC:4.2.3.9] +synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)" EXACT [EC:4.2.3.9] +xref: EC:4.2.3.9 +xref: MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN +xref: RHEA:19825 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0045484 +name: L-lysine 6-transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine." [EC:2.6.1.36, RHEA:21200] +synonym: "L-lysine aminotransferase activity" EXACT [EC:2.6.1.36] +synonym: "L-lysine transaminase activity" EXACT [EC:2.6.1.36] +synonym: "L-lysine-alpha-ketoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] +synonym: "L-lysine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.36] +synonym: "L-lysine:2-oxoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] +synonym: "lysine 6-aminotransferase activity" EXACT [] +synonym: "lysine epsilon-aminotransferase activity" EXACT [EC:2.6.1.36] +synonym: "lysine epsilon-transaminase activity" EXACT [EC:2.6.1.36] +synonym: "lysine:2-ketoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] +xref: EC:2.6.1.36 +xref: KEGG_REACTION:R00457 +xref: MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN +xref: RHEA:21200 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0045485 +name: omega-6 fatty acid desaturase activity +namespace: molecular_function +def: "Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain." [PMID:7846158] +xref: Reactome:R-HSA-2046089 "Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA" +xref: Reactome:R-HSA-2046092 "Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA" +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0045486 +name: naringenin 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2." [EC:1.14.11.9] +synonym: "(2S)-flavanone 3-hydroxylase activity" EXACT [EC:1.14.11.9] +synonym: "flavanone 3-beta-hydroxylase activity" EXACT [EC:1.14.11.9] +synonym: "flavanone 3-dioxygenase activity" EXACT [EC:1.14.11.9] +synonym: "flavanone 3-hydroxylase activity" EXACT [EC:1.14.11.9] +synonym: "flavanone 3beta-hydroxylase activity" EXACT [EC:1.14.11.9] +synonym: "flavanone synthase I activity" EXACT [EC:1.14.11.9] +synonym: "flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.9] +synonym: "naringenin 3-hydroxylase activity" EXACT [EC:1.14.11.9] +synonym: "naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.9] +xref: EC:1.14.11.9 +xref: MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0045487 +name: gibberellin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators." [GOC:go_curators] +synonym: "gibberellic acid breakdown" NARROW [] +synonym: "gibberellic acid catabolic process" NARROW [] +synonym: "gibberellic acid catabolism" NARROW [] +synonym: "gibberellic acid degradation" NARROW [] +synonym: "gibberellin catabolism" EXACT [] +is_a: GO:0009685 ! gibberellin metabolic process +is_a: GO:0016103 ! diterpenoid catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process + +[Term] +id: GO:0045488 +name: pectin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge." [GOC:tair_curators] +synonym: "pectin metabolism" EXACT [] +is_a: GO:0010393 ! galacturonan metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0045489 +name: pectin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues." [GOC:go_curators, PMID:11931668] +synonym: "pectin anabolism" EXACT [] +synonym: "pectin biosynthesis" EXACT [] +synonym: "pectin formation" EXACT [] +synonym: "pectin synthesis" EXACT [] +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0045488 ! pectin metabolic process + +[Term] +id: GO:0045490 +name: pectin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues." [GOC:go_curators, PMID:11931668] +synonym: "pectin breakdown" EXACT [] +synonym: "pectin catabolism" EXACT [] +synonym: "pectin degradation" EXACT [] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0045488 ! pectin metabolic process + +[Term] +id: GO:0045491 +name: xylan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone." [GOC:go_curators, PMID:11931668] +synonym: "xylan metabolism" EXACT [] +is_a: GO:0010410 ! hemicellulose metabolic process + +[Term] +id: GO:0045492 +name: xylan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone." [GOC:go_curators, PMID:11931668] +synonym: "xylan anabolism" EXACT [] +synonym: "xylan biosynthesis" EXACT [] +synonym: "xylan formation" EXACT [] +synonym: "xylan synthesis" EXACT [] +is_a: GO:0045491 ! xylan metabolic process +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process + +[Term] +id: GO:0045493 +name: xylan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone." [GOC:go_curators, PMID:11931668] +synonym: "xylan breakdown" EXACT [] +synonym: "xylan catabolism" EXACT [] +synonym: "xylan degradation" EXACT [] +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +is_a: GO:0045491 ! xylan metabolic process + +[Term] +id: GO:0045494 +name: photoreceptor cell maintenance +namespace: biological_process +def: "Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light." [CL:0000210, GOC:bf, GOC:rl] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0001895 ! retina homeostasis + +[Term] +id: GO:0045495 +name: pole plasm +namespace: cellular_component +def: "Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo." [GOC:kmv, PMID:17113380] +synonym: "germ plasm" NARROW [] +synonym: "polar plasm" EXACT [] +is_a: GO:0005737 ! cytoplasm +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0045496 +name: male analia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11494318] +is_a: GO:0007487 ! analia development + +[Term] +id: GO:0045497 +name: female analia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11494318] +is_a: GO:0007487 ! analia development + +[Term] +id: GO:0045498 +name: sex comb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg." [http://fly.ebi.ac.uk] +is_a: GO:0007423 ! sensory organ development + +[Term] +id: GO:0045499 +name: chemorepellent activity +namespace: molecular_function +def: "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal." [GOC:ai] +subset: goslim_pir +synonym: "chemorepellant activity" EXACT [] +is_a: GO:0048018 ! receptor ligand activity +relationship: part_of GO:0050919 ! negative chemotaxis + +[Term] +id: GO:0045500 +name: sevenless signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:signaling, PMID:10771085] +synonym: "sev receptor signaling pathway" EXACT [] +synonym: "sev signaling pathway" EXACT [] +synonym: "sevenless signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +relationship: part_of GO:0007465 ! R7 cell fate commitment + +[Term] +id: GO:0045501 +name: regulation of sevenless signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] +synonym: "regulation of sev signaling pathway" EXACT [] +synonym: "regulation of sevenless signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0045676 ! regulation of R7 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045500 ! sevenless signaling pathway +relationship: regulates GO:0045500 ! sevenless signaling pathway + +[Term] +id: GO:0045503 +name: dynein light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light chain of the dynein complex." [GOC:bf] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0045504 +name: dynein heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heavy chain of the dynein complex." [GOC:bf] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0045505 +name: dynein intermediate chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an intermediate chain of the dynein complex." [GOC:bf] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0045506 +name: interleukin-24 receptor activity +namespace: molecular_function +def: "Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-24 receptor activity" EXACT [GOC:mah] +synonym: "IL-24R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0045510 ! interleukin-24 binding + +[Term] +id: GO:0045507 +name: interleukin-25 receptor activity +namespace: molecular_function +def: "Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-25 receptor activity" EXACT [GOC:mah] +synonym: "IL-25R" EXACT [] +is_a: GO:0030368 ! interleukin-17 receptor activity +relationship: has_part GO:0045511 ! interleukin-25 binding + +[Term] +id: GO:0045508 +name: interleukin-26 receptor activity +namespace: molecular_function +def: "Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-26 receptor activity" EXACT [GOC:mah] +synonym: "IL-26R" EXACT [] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0045512 ! interleukin-26 binding + +[Term] +id: GO:0045509 +name: interleukin-27 receptor activity +namespace: molecular_function +def: "Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:jl, GOC:signaling] +synonym: "IL-27 receptor activity" EXACT [GOC:mah] +synonym: "IL-27R" EXACT [] +is_a: GO:0030368 ! interleukin-17 receptor activity +relationship: has_part GO:0045513 ! interleukin-27 binding +relationship: part_of GO:0070106 ! interleukin-27-mediated signaling pathway + +[Term] +id: GO:0045510 +name: interleukin-24 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-24." [GOC:go_curators] +synonym: "IL-24 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0045511 +name: interleukin-25 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-25." [GOC:go_curators] +synonym: "IL-25 binding" EXACT [] +is_a: GO:0019975 ! interleukin-17 binding + +[Term] +id: GO:0045512 +name: interleukin-26 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-26." [GOC:go_curators] +synonym: "IL-26 binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0045513 +name: interleukin-27 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-27." [GOC:go_curators] +synonym: "IL-27 binding" EXACT [] +is_a: GO:0019975 ! interleukin-17 binding + +[Term] +id: GO:0045514 +name: interleukin-16 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-16 receptor." [GOC:go_curators] +synonym: "IL-16" NARROW [] +synonym: "interleukin-16 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045515 +name: interleukin-18 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-18 receptor." [GOC:go_curators] +synonym: "IL-18" NARROW [] +synonym: "interleukin-18 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045516 +name: interleukin-19 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-19 receptor." [GOC:go_curators] +synonym: "IL-19" NARROW [] +synonym: "interleukin-19 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045517 +name: interleukin-20 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-20 receptor." [GOC:go_curators] +synonym: "IL-20" NARROW [] +synonym: "interleukin-20 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045518 +name: interleukin-22 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-22 receptor." [GOC:go_curators] +synonym: "IL-22" NARROW [] +synonym: "interleukin-22 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045519 +name: interleukin-23 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-23 receptor." [GOC:go_curators] +synonym: "IL-23" NARROW [] +synonym: "interleukin-23 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045520 +name: interleukin-24 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-24 receptor." [GOC:go_curators] +synonym: "IL-24" NARROW [] +synonym: "interleukin-24 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045521 +name: interleukin-25 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-25 receptor." [GOC:go_curators] +synonym: "IL-25" NARROW [] +synonym: "interleukin-25 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045522 +name: interleukin-26 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-26 receptor." [GOC:go_curators] +synonym: "IL-26" NARROW [] +synonym: "interleukin-26 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045523 +name: interleukin-27 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-27 receptor." [GOC:go_curators] +synonym: "IL-27" NARROW [] +synonym: "interleukin-27 receptor ligand" NARROW [] +is_a: GO:0005126 ! cytokine receptor binding + +[Term] +id: GO:0045524 +name: interleukin-24 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] +synonym: "IL-24 biosynthesis" EXACT [] +synonym: "IL-24 biosynthetic process" EXACT [] +synonym: "interleukin-24 anabolism" EXACT [] +synonym: "interleukin-24 biosynthesis" EXACT [] +synonym: "interleukin-24 formation" EXACT [] +synonym: "interleukin-24 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032628 ! interleukin-24 production + +[Term] +id: GO:0045525 +name: interleukin-25 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] +synonym: "IL-25 biosynthesis" EXACT [] +synonym: "IL-25 biosynthetic process" EXACT [] +synonym: "interleukin-25 anabolism" EXACT [] +synonym: "interleukin-25 biosynthesis" EXACT [] +synonym: "interleukin-25 formation" EXACT [] +synonym: "interleukin-25 synthesis" EXACT [] +is_a: GO:0042235 ! interleukin-17 biosynthetic process +relationship: part_of GO:0032629 ! interleukin-25 production + +[Term] +id: GO:0045526 +name: interleukin-26 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] +synonym: "IL-26 biosynthesis" EXACT [] +synonym: "IL-26 biosynthetic process" EXACT [] +synonym: "interleukin-26 anabolism" EXACT [] +synonym: "interleukin-26 biosynthesis" EXACT [] +synonym: "interleukin-26 formation" EXACT [] +synonym: "interleukin-26 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032630 ! interleukin-26 production + +[Term] +id: GO:0045527 +name: interleukin-27 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] +synonym: "IL-27 biosynthesis" EXACT [] +synonym: "IL-27 biosynthetic process" EXACT [] +synonym: "interleukin-27 anabolism" EXACT [] +synonym: "interleukin-27 biosynthesis" EXACT [] +synonym: "interleukin-27 formation" EXACT [] +synonym: "interleukin-27 synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032631 ! interleukin-27 production + +[Term] +id: GO:0045528 +name: regulation of interleukin-24 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] +synonym: "regulation of IL-24 biosynthesis" EXACT [] +synonym: "regulation of IL-24 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-24 anabolism" EXACT [] +synonym: "regulation of interleukin-24 biosynthesis" EXACT [] +synonym: "regulation of interleukin-24 formation" EXACT [] +synonym: "regulation of interleukin-24 synthesis" EXACT [] +is_a: GO:0032668 ! regulation of interleukin-24 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045524 ! interleukin-24 biosynthetic process +relationship: regulates GO:0045524 ! interleukin-24 biosynthetic process + +[Term] +id: GO:0045529 +name: regulation of interleukin-25 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] +synonym: "regulation of IL-25 biosynthesis" EXACT [] +synonym: "regulation of IL-25 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-25 anabolism" EXACT [] +synonym: "regulation of interleukin-25 biosynthesis" EXACT [] +synonym: "regulation of interleukin-25 formation" EXACT [] +synonym: "regulation of interleukin-25 synthesis" EXACT [] +is_a: GO:0032669 ! regulation of interleukin-25 production +is_a: GO:0045378 ! regulation of interleukin-17 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045525 ! interleukin-25 biosynthetic process +relationship: regulates GO:0045525 ! interleukin-25 biosynthetic process + +[Term] +id: GO:0045530 +name: regulation of interleukin-26 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] +synonym: "regulation of IL-26 biosynthesis" EXACT [] +synonym: "regulation of IL-26 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-26 anabolism" EXACT [] +synonym: "regulation of interleukin-26 biosynthesis" EXACT [] +synonym: "regulation of interleukin-26 formation" EXACT [] +synonym: "regulation of interleukin-26 synthesis" EXACT [] +is_a: GO:0032670 ! regulation of interleukin-26 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045526 ! interleukin-26 biosynthetic process +relationship: regulates GO:0045526 ! interleukin-26 biosynthetic process + +[Term] +id: GO:0045531 +name: regulation of interleukin-27 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] +synonym: "regulation of IL-27 biosynthesis" EXACT [] +synonym: "regulation of IL-27 biosynthetic process" EXACT [] +synonym: "regulation of interleukin-27 anabolism" EXACT [] +synonym: "regulation of interleukin-27 biosynthesis" EXACT [] +synonym: "regulation of interleukin-27 formation" EXACT [] +synonym: "regulation of interleukin-27 synthesis" EXACT [] +is_a: GO:0032671 ! regulation of interleukin-27 production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045527 ! interleukin-27 biosynthetic process +relationship: regulates GO:0045527 ! interleukin-27 biosynthetic process + +[Term] +id: GO:0045532 +name: negative regulation of interleukin-24 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] +synonym: "down regulation of interleukin-24 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-24 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-24 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-24 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-24 biosynthesis" EXACT [] +synonym: "negative regulation of IL-24 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-24 anabolism" EXACT [] +synonym: "negative regulation of interleukin-24 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-24 formation" EXACT [] +synonym: "negative regulation of interleukin-24 synthesis" EXACT [] +is_a: GO:0032708 ! negative regulation of interleukin-24 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045528 ! regulation of interleukin-24 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045524 ! interleukin-24 biosynthetic process +relationship: negatively_regulates GO:0045524 ! interleukin-24 biosynthetic process + +[Term] +id: GO:0045533 +name: negative regulation of interleukin-25 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] +synonym: "down regulation of interleukin-25 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-25 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-25 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-25 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-25 biosynthesis" EXACT [] +synonym: "negative regulation of IL-25 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-25 anabolism" EXACT [] +synonym: "negative regulation of interleukin-25 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-25 formation" EXACT [] +synonym: "negative regulation of interleukin-25 synthesis" EXACT [] +is_a: GO:0032709 ! negative regulation of interleukin-25 production +is_a: GO:0045379 ! negative regulation of interleukin-17 biosynthetic process +is_a: GO:0045529 ! regulation of interleukin-25 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045525 ! interleukin-25 biosynthetic process +relationship: negatively_regulates GO:0045525 ! interleukin-25 biosynthetic process + +[Term] +id: GO:0045534 +name: negative regulation of interleukin-26 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] +synonym: "down regulation of interleukin-26 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-26 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-26 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-26 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-26 biosynthesis" EXACT [] +synonym: "negative regulation of IL-26 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-26 anabolism" EXACT [] +synonym: "negative regulation of interleukin-26 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-26 formation" EXACT [] +synonym: "negative regulation of interleukin-26 synthesis" EXACT [] +is_a: GO:0032710 ! negative regulation of interleukin-26 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045530 ! regulation of interleukin-26 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045526 ! interleukin-26 biosynthetic process +relationship: negatively_regulates GO:0045526 ! interleukin-26 biosynthetic process + +[Term] +id: GO:0045535 +name: negative regulation of interleukin-27 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] +synonym: "down regulation of interleukin-27 biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-27 biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-27 biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-27 biosynthetic process" NARROW [] +synonym: "negative regulation of IL-27 biosynthesis" EXACT [] +synonym: "negative regulation of IL-27 biosynthetic process" EXACT [] +synonym: "negative regulation of interleukin-27 anabolism" EXACT [] +synonym: "negative regulation of interleukin-27 biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-27 formation" EXACT [] +synonym: "negative regulation of interleukin-27 synthesis" EXACT [] +is_a: GO:0032711 ! negative regulation of interleukin-27 production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045531 ! regulation of interleukin-27 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045527 ! interleukin-27 biosynthetic process +relationship: negatively_regulates GO:0045527 ! interleukin-27 biosynthetic process + +[Term] +id: GO:0045536 +name: positive regulation of interleukin-24 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] +synonym: "activation of interleukin-24 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-24 biosynthesis" EXACT [] +synonym: "positive regulation of IL-24 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-24 anabolism" EXACT [] +synonym: "positive regulation of interleukin-24 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-24 formation" EXACT [] +synonym: "positive regulation of interleukin-24 synthesis" EXACT [] +synonym: "stimulation of interleukin-24 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-24 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-24 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-24 biosynthetic process" EXACT [] +is_a: GO:0032748 ! positive regulation of interleukin-24 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045528 ! regulation of interleukin-24 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045524 ! interleukin-24 biosynthetic process +relationship: positively_regulates GO:0045524 ! interleukin-24 biosynthetic process + +[Term] +id: GO:0045537 +name: positive regulation of interleukin-25 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] +synonym: "activation of interleukin-25 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-25 biosynthesis" EXACT [] +synonym: "positive regulation of IL-25 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-25 anabolism" EXACT [] +synonym: "positive regulation of interleukin-25 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-25 formation" EXACT [] +synonym: "positive regulation of interleukin-25 synthesis" EXACT [] +synonym: "stimulation of interleukin-25 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-25 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-25 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-25 biosynthetic process" EXACT [] +is_a: GO:0032749 ! positive regulation of interleukin-25 production +is_a: GO:0045380 ! positive regulation of interleukin-17 biosynthetic process +is_a: GO:0045529 ! regulation of interleukin-25 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045525 ! interleukin-25 biosynthetic process +relationship: positively_regulates GO:0045525 ! interleukin-25 biosynthetic process + +[Term] +id: GO:0045538 +name: positive regulation of interleukin-26 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] +synonym: "activation of interleukin-26 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-26 biosynthesis" EXACT [] +synonym: "positive regulation of IL-26 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-26 anabolism" EXACT [] +synonym: "positive regulation of interleukin-26 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-26 formation" EXACT [] +synonym: "positive regulation of interleukin-26 synthesis" EXACT [] +synonym: "stimulation of interleukin-26 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-26 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-26 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-26 biosynthetic process" EXACT [] +is_a: GO:0032750 ! positive regulation of interleukin-26 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045530 ! regulation of interleukin-26 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045526 ! interleukin-26 biosynthetic process +relationship: positively_regulates GO:0045526 ! interleukin-26 biosynthetic process + +[Term] +id: GO:0045539 +name: positive regulation of interleukin-27 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] +synonym: "activation of interleukin-27 biosynthetic process" NARROW [] +synonym: "positive regulation of IL-27 biosynthesis" EXACT [] +synonym: "positive regulation of IL-27 biosynthetic process" EXACT [] +synonym: "positive regulation of interleukin-27 anabolism" EXACT [] +synonym: "positive regulation of interleukin-27 biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-27 formation" EXACT [] +synonym: "positive regulation of interleukin-27 synthesis" EXACT [] +synonym: "stimulation of interleukin-27 biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-27 biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-27 biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-27 biosynthetic process" EXACT [] +is_a: GO:0032751 ! positive regulation of interleukin-27 production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045531 ! regulation of interleukin-27 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045527 ! interleukin-27 biosynthetic process +relationship: positively_regulates GO:0045527 ! interleukin-27 biosynthetic process + +[Term] +id: GO:0045540 +name: regulation of cholesterol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] +synonym: "regulation of cholesterol anabolism" EXACT [] +synonym: "regulation of cholesterol biosynthesis" EXACT [] +synonym: "regulation of cholesterol formation" EXACT [] +synonym: "regulation of cholesterol synthesis" EXACT [] +is_a: GO:0090181 ! regulation of cholesterol metabolic process +is_a: GO:0106118 ! regulation of sterol biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006695 ! cholesterol biosynthetic process +relationship: regulates GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0045541 +name: negative regulation of cholesterol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] +synonym: "down regulation of cholesterol biosynthetic process" EXACT [] +synonym: "down-regulation of cholesterol biosynthetic process" EXACT [] +synonym: "downregulation of cholesterol biosynthetic process" EXACT [] +synonym: "inhibition of cholesterol biosynthetic process" NARROW [] +synonym: "negative regulation of cholesterol anabolism" EXACT [] +synonym: "negative regulation of cholesterol biosynthesis" EXACT [] +synonym: "negative regulation of cholesterol formation" EXACT [] +synonym: "negative regulation of cholesterol synthesis" EXACT [] +is_a: GO:0045540 ! regulation of cholesterol biosynthetic process +is_a: GO:0090206 ! negative regulation of cholesterol metabolic process +is_a: GO:0106119 ! negative regulation of sterol biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006695 ! cholesterol biosynthetic process +relationship: negatively_regulates GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0045542 +name: positive regulation of cholesterol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] +synonym: "activation of cholesterol biosynthetic process" NARROW [] +synonym: "positive regulation of cholesterol anabolism" EXACT [] +synonym: "positive regulation of cholesterol biosynthesis" EXACT [] +synonym: "positive regulation of cholesterol formation" EXACT [] +synonym: "positive regulation of cholesterol synthesis" EXACT [] +synonym: "stimulation of cholesterol biosynthetic process" NARROW [] +synonym: "up regulation of cholesterol biosynthetic process" EXACT [] +synonym: "up-regulation of cholesterol biosynthetic process" EXACT [] +synonym: "upregulation of cholesterol biosynthetic process" EXACT [] +is_a: GO:0045540 ! regulation of cholesterol biosynthetic process +is_a: GO:0090205 ! positive regulation of cholesterol metabolic process +is_a: GO:0106120 ! positive regulation of sterol biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006695 ! cholesterol biosynthetic process +relationship: positively_regulates GO:0006695 ! cholesterol biosynthetic process + +[Term] +id: GO:0045543 +name: gibberellin 2-beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2." [EC:1.14.11.13, GOC:kad] +synonym: "(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)" NARROW [EC:1.14.11.13] +synonym: "gibberellin 2-beta-hydroxylase activity" EXACT [EC:1.14.11.13] +synonym: "gibberellin 2-oxidase activity" EXACT [] +synonym: "gibberellin 2beta-dioxygenase activity" EXACT [EC:1.14.11.13] +synonym: "gibberellin 2beta-hydroxylase activity" EXACT [EC:1.14.11.13] +xref: EC:1.14.11.13 +xref: MetaCyc:PWY-102 +xref: RHEA:15005 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0045544 +name: gibberellin 20-oxidase activity +namespace: molecular_function +def: "Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones." [PMID:7604047] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0045545 +name: syndecan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells." [GOC:go_curators, PMID:9355727] +is_a: GO:0043394 ! proteoglycan binding + +[Term] +id: GO:0045547 +name: dehydrodolichyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate." [PMID:9858571] +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0045548 +name: phenylalanine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate." [RHEA:21384] +synonym: "L-phenylalanine ammonia-lyase activity" EXACT [EC:4.3.1.24] +synonym: "PAL activity" BROAD [EC:4.3.1.24] +synonym: "phe ammonia-lyase activity" EXACT [EC:4.3.1.24] +synonym: "phenylalanine ammonium-lyase activity" EXACT [EC:4.3.1.24] +synonym: "phenylalanine deaminase activity" EXACT [EC:4.3.1.24] +xref: EC:4.3.1.24 +xref: EC:4.3.1.25 +xref: RHEA:21384 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0045549 +name: 9-cis-epoxycarotenoid dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al." [EC:1.13.11.51] +synonym: "9-cis-epoxycarotenoid 11,12-dioxygenase activity" EXACT [EC:1.13.11.51] +synonym: "AtNCED3" RELATED [EC:1.13.11.51] +synonym: "NCED" RELATED [EC:1.13.11.51] +synonym: "neoxanthin cleavage enzyme" RELATED [] +synonym: "nine-cis-epoxycarotenoid dioxygenase activity" EXACT [EC:1.13.11.51] +synonym: "PvNCED1" RELATED [EC:1.13.11.51] +synonym: "VP14" RELATED [EC:1.13.11.51] +xref: EC:1.13.11.51 +is_a: GO:0010436 ! carotenoid dioxygenase activity + +[Term] +id: GO:0045550 +name: geranylgeranyl reductase activity +namespace: molecular_function +def: "Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group." [PMID:9492312] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0045551 +name: cinnamyl-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+." [EC:1.1.1.195] +synonym: "CAD activity" BROAD [EC:1.1.1.195] +synonym: "cinnamyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.195] +synonym: "cinnamyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.195] +xref: EC:1.1.1.195 +xref: MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN +xref: RHEA:10392 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0045552 +name: dihydrokaempferol 4-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+." [EC:1.1.1.219] +synonym: "cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.219] +synonym: "dihydroflavanol 4-reductase activity" EXACT [EC:1.1.1.219] +synonym: "dihydroflavonol 4-reductase activity" EXACT [EC:1.1.1.219] +synonym: "dihydromyricetin reductase activity" EXACT [EC:1.1.1.219] +synonym: "dihydroquercetin reductase activity" EXACT [EC:1.1.1.219] +synonym: "NADPH-dihydromyricetin reductase activity" EXACT [EC:1.1.1.219] +xref: EC:1.1.1.219 +xref: MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN +xref: RHEA:23016 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0045553 +name: TRAIL biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand). TRAIL induces apoptosis in a wide variety of cells and is a member of the tumor necrosis factor (TNF) family of cytokines." [PMID:9311998] +synonym: "TRAIL anabolism" EXACT [] +synonym: "TRAIL biosynthesis" EXACT [] +synonym: "TRAIL formation" EXACT [] +synonym: "TRAIL synthesis" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0032639 ! TRAIL production + +[Term] +id: GO:0045554 +name: regulation of TRAIL biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] +synonym: "regulation of TRAIL anabolism" EXACT [] +synonym: "regulation of TRAIL biosynthesis" EXACT [] +synonym: "regulation of TRAIL formation" EXACT [] +synonym: "regulation of TRAIL synthesis" EXACT [] +is_a: GO:0032679 ! regulation of TRAIL production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045553 ! TRAIL biosynthetic process +relationship: regulates GO:0045553 ! TRAIL biosynthetic process + +[Term] +id: GO:0045555 +name: negative regulation of TRAIL biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] +synonym: "down regulation of TRAIL biosynthetic process" EXACT [] +synonym: "down-regulation of TRAIL biosynthetic process" EXACT [] +synonym: "downregulation of TRAIL biosynthetic process" EXACT [] +synonym: "inhibition of TRAIL biosynthetic process" NARROW [] +synonym: "negative regulation of TRAIL anabolism" EXACT [] +synonym: "negative regulation of TRAIL biosynthesis" EXACT [] +synonym: "negative regulation of TRAIL formation" EXACT [] +synonym: "negative regulation of TRAIL synthesis" EXACT [] +is_a: GO:0032719 ! negative regulation of TRAIL production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0045554 ! regulation of TRAIL biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045553 ! TRAIL biosynthetic process +relationship: negatively_regulates GO:0045553 ! TRAIL biosynthetic process + +[Term] +id: GO:0045556 +name: positive regulation of TRAIL biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] +synonym: "activation of TRAIL biosynthetic process" NARROW [] +synonym: "positive regulation of TRAIL anabolism" EXACT [] +synonym: "positive regulation of TRAIL biosynthesis" EXACT [] +synonym: "positive regulation of TRAIL formation" EXACT [] +synonym: "positive regulation of TRAIL synthesis" EXACT [] +synonym: "stimulation of TRAIL biosynthetic process" NARROW [] +synonym: "up regulation of TRAIL biosynthetic process" EXACT [] +synonym: "up-regulation of TRAIL biosynthetic process" EXACT [] +synonym: "upregulation of TRAIL biosynthetic process" EXACT [] +is_a: GO:0032759 ! positive regulation of TRAIL production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0045554 ! regulation of TRAIL biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045553 ! TRAIL biosynthetic process +relationship: positively_regulates GO:0045553 ! TRAIL biosynthetic process + +[Term] +id: GO:0045557 +name: TRAIL receptor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor." [GOC:go_curators] +synonym: "TRAIL receptor anabolism" EXACT [] +synonym: "TRAIL receptor biosynthesis" EXACT [] +synonym: "TRAIL receptor formation" EXACT [] +synonym: "TRAIL receptor synthesis" EXACT [] +is_a: GO:0032800 ! receptor biosynthetic process + +[Term] +id: GO:0045558 +name: TRAIL receptor 1 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway." [GOC:go_curators, PMID:9311998] +synonym: "TRAIL receptor 1 anabolism" EXACT [] +synonym: "TRAIL receptor 1 biosynthesis" EXACT [] +synonym: "TRAIL receptor 1 formation" EXACT [] +synonym: "TRAIL receptor 1 synthesis" EXACT [] +synonym: "tumor necrosis factor receptor superfamily member 10A biosynthetic process" EXACT [PR:000002108] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0045557 ! TRAIL receptor biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0045559 +name: TRAIL receptor 2 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1." [GOC:go_curators, PMID:9311998] +synonym: "TRAIL receptor 2 anabolism" EXACT [] +synonym: "TRAIL receptor 2 biosynthesis" EXACT [] +synonym: "TRAIL receptor 2 formation" EXACT [] +synonym: "TRAIL receptor 2 synthesis" EXACT [] +synonym: "tumor necrosis factor receptor superfamily member 10B biosynthetic process" EXACT [PR:000002109] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0045557 ! TRAIL receptor biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0045560 +name: regulation of TRAIL receptor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor." [GOC:go_curators] +synonym: "regulation of TRAIL receptor anabolism" EXACT [] +synonym: "regulation of TRAIL receptor biosynthesis" EXACT [] +synonym: "regulation of TRAIL receptor formation" EXACT [] +synonym: "regulation of TRAIL receptor synthesis" EXACT [] +is_a: GO:0010869 ! regulation of receptor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045557 ! TRAIL receptor biosynthetic process +relationship: regulates GO:0045557 ! TRAIL receptor biosynthetic process + +[Term] +id: GO:0045561 +name: regulation of TRAIL receptor 1 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1." [GOC:go_curators] +synonym: "regulation of TRAIL receptor 1 anabolism" EXACT [] +synonym: "regulation of TRAIL receptor 1 biosynthesis" EXACT [] +synonym: "regulation of TRAIL receptor 1 formation" EXACT [] +synonym: "regulation of TRAIL receptor 1 synthesis" EXACT [] +is_a: GO:0045560 ! regulation of TRAIL receptor biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process +relationship: regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process + +[Term] +id: GO:0045562 +name: regulation of TRAIL receptor 2 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2." [GOC:go_curators] +synonym: "regulation of TRAIL receptor 2 anabolism" EXACT [] +synonym: "regulation of TRAIL receptor 2 biosynthesis" EXACT [] +synonym: "regulation of TRAIL receptor 2 formation" EXACT [] +synonym: "regulation of TRAIL receptor 2 synthesis" EXACT [] +is_a: GO:0045560 ! regulation of TRAIL receptor biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process +relationship: regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process + +[Term] +id: GO:0045563 +name: negative regulation of TRAIL receptor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor." [GOC:go_curators] +synonym: "down regulation of TRAIL receptor biosynthetic process" EXACT [] +synonym: "down-regulation of TRAIL receptor biosynthetic process" EXACT [] +synonym: "downregulation of TRAIL receptor biosynthetic process" EXACT [] +synonym: "inhibition of TRAIL receptor biosynthetic process" NARROW [] +synonym: "negative regulation of TRAIL receptor anabolism" EXACT [] +synonym: "negative regulation of TRAIL receptor biosynthesis" EXACT [] +synonym: "negative regulation of TRAIL receptor formation" EXACT [] +synonym: "negative regulation of TRAIL receptor synthesis" EXACT [] +is_a: GO:0010871 ! negative regulation of receptor biosynthetic process +is_a: GO:0045560 ! regulation of TRAIL receptor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045557 ! TRAIL receptor biosynthetic process +relationship: negatively_regulates GO:0045557 ! TRAIL receptor biosynthetic process + +[Term] +id: GO:0045564 +name: positive regulation of TRAIL receptor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor." [GOC:go_curators] +synonym: "activation of TRAIL receptor biosynthetic process" NARROW [] +synonym: "positive regulation of TRAIL receptor anabolism" EXACT [] +synonym: "positive regulation of TRAIL receptor biosynthesis" EXACT [] +synonym: "positive regulation of TRAIL receptor formation" EXACT [] +synonym: "positive regulation of TRAIL receptor synthesis" EXACT [] +synonym: "stimulation of TRAIL receptor biosynthetic process" NARROW [] +synonym: "up regulation of TRAIL receptor biosynthetic process" EXACT [] +synonym: "up-regulation of TRAIL receptor biosynthetic process" EXACT [] +synonym: "upregulation of TRAIL receptor biosynthetic process" EXACT [] +is_a: GO:0010870 ! positive regulation of receptor biosynthetic process +is_a: GO:0045560 ! regulation of TRAIL receptor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045557 ! TRAIL receptor biosynthetic process +relationship: positively_regulates GO:0045557 ! TRAIL receptor biosynthetic process + +[Term] +id: GO:0045565 +name: negative regulation of TRAIL receptor 1 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1." [GOC:go_curators] +synonym: "down regulation of TRAIL receptor 1 biosynthetic process" EXACT [] +synonym: "down-regulation of TRAIL receptor 1 biosynthetic process" EXACT [] +synonym: "downregulation of TRAIL receptor 1 biosynthetic process" EXACT [] +synonym: "inhibition of TRAIL receptor 1 biosynthetic process" NARROW [] +synonym: "negative regulation of TRAIL receptor 1 anabolism" EXACT [] +synonym: "negative regulation of TRAIL receptor 1 biosynthesis" EXACT [] +synonym: "negative regulation of TRAIL receptor 1 formation" EXACT [] +synonym: "negative regulation of TRAIL receptor 1 synthesis" EXACT [] +is_a: GO:0045561 ! regulation of TRAIL receptor 1 biosynthetic process +is_a: GO:0045563 ! negative regulation of TRAIL receptor biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process +relationship: negatively_regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process + +[Term] +id: GO:0045566 +name: positive regulation of TRAIL receptor 1 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1." [GOC:go_curators] +synonym: "activation of TRAIL receptor 1 biosynthetic process" NARROW [] +synonym: "positive regulation of TRAIL receptor 1 anabolism" EXACT [] +synonym: "positive regulation of TRAIL receptor 1 biosynthesis" EXACT [] +synonym: "positive regulation of TRAIL receptor 1 formation" EXACT [] +synonym: "positive regulation of TRAIL receptor 1 synthesis" EXACT [] +synonym: "stimulation of TRAIL receptor 1 biosynthetic process" NARROW [] +synonym: "up regulation of TRAIL receptor 1 biosynthetic process" EXACT [] +synonym: "up-regulation of TRAIL receptor 1 biosynthetic process" EXACT [] +synonym: "upregulation of TRAIL receptor 1 biosynthetic process" EXACT [] +is_a: GO:0045561 ! regulation of TRAIL receptor 1 biosynthetic process +is_a: GO:0045564 ! positive regulation of TRAIL receptor biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process +relationship: positively_regulates GO:0045558 ! TRAIL receptor 1 biosynthetic process + +[Term] +id: GO:0045567 +name: negative regulation of TRAIL receptor 2 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2." [GOC:go_curators] +synonym: "down regulation of TRAIL receptor 2 biosynthetic process" EXACT [] +synonym: "down-regulation of TRAIL receptor 2 biosynthetic process" EXACT [] +synonym: "downregulation of TRAIL receptor 2 biosynthetic process" EXACT [] +synonym: "inhibition of TRAIL receptor 2 biosynthetic process" NARROW [] +synonym: "negative regulation of TRAIL receptor 2 anabolism" EXACT [] +synonym: "negative regulation of TRAIL receptor 2 biosynthesis" EXACT [] +synonym: "negative regulation of TRAIL receptor 2 formation" EXACT [] +synonym: "negative regulation of TRAIL receptor 2 synthesis" EXACT [] +is_a: GO:0045562 ! regulation of TRAIL receptor 2 biosynthetic process +is_a: GO:0045563 ! negative regulation of TRAIL receptor biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process +relationship: negatively_regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process + +[Term] +id: GO:0045568 +name: positive regulation of TRAIL receptor 2 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2." [GOC:go_curators] +synonym: "activation of TRAIL receptor 2 biosynthetic process" NARROW [] +synonym: "positive regulation of TRAIL receptor 2 anabolism" EXACT [] +synonym: "positive regulation of TRAIL receptor 2 biosynthesis" EXACT [] +synonym: "positive regulation of TRAIL receptor 2 formation" EXACT [] +synonym: "positive regulation of TRAIL receptor 2 synthesis" EXACT [] +synonym: "stimulation of TRAIL receptor 2 biosynthetic process" NARROW [] +synonym: "up regulation of TRAIL receptor 2 biosynthetic process" EXACT [] +synonym: "up-regulation of TRAIL receptor 2 biosynthetic process" EXACT [] +synonym: "upregulation of TRAIL receptor 2 biosynthetic process" EXACT [] +is_a: GO:0045562 ! regulation of TRAIL receptor 2 biosynthetic process +is_a: GO:0045564 ! positive regulation of TRAIL receptor biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process +relationship: positively_regulates GO:0045559 ! TRAIL receptor 2 biosynthetic process + +[Term] +id: GO:0045569 +name: TRAIL binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines." [GOC:go_curators, PMID:9082980] +subset: goslim_chembl +synonym: "Apo-2L binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0045570 +name: regulation of imaginal disc growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the growth of the imaginal disc." [GOC:go_curators] +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007446 ! imaginal disc growth +relationship: regulates GO:0007446 ! imaginal disc growth + +[Term] +id: GO:0045571 +name: negative regulation of imaginal disc growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth." [GOC:go_curators] +synonym: "down regulation of imaginal disc growth" EXACT [] +synonym: "down-regulation of imaginal disc growth" EXACT [] +synonym: "downregulation of imaginal disc growth" EXACT [] +synonym: "inhibition of imaginal disc growth" NARROW [] +is_a: GO:0045570 ! regulation of imaginal disc growth +is_a: GO:0046621 ! negative regulation of organ growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007446 ! imaginal disc growth +relationship: negatively_regulates GO:0007446 ! imaginal disc growth + +[Term] +id: GO:0045572 +name: positive regulation of imaginal disc growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of imaginal disc growth." [GOC:go_curators] +synonym: "activation of imaginal disc growth" NARROW [] +synonym: "stimulation of imaginal disc growth" NARROW [] +synonym: "up regulation of imaginal disc growth" EXACT [] +synonym: "up-regulation of imaginal disc growth" EXACT [] +synonym: "upregulation of imaginal disc growth" EXACT [] +is_a: GO:0045570 ! regulation of imaginal disc growth +is_a: GO:0046622 ! positive regulation of organ growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007446 ! imaginal disc growth +relationship: positively_regulates GO:0007446 ! imaginal disc growth + +[Term] +id: GO:0045574 +name: sterigmatocystin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds." [GOC:go_curators] +synonym: "sterigmatocystin breakdown" EXACT [] +synonym: "sterigmatocystin catabolism" EXACT [] +synonym: "sterigmatocystin degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0045460 ! sterigmatocystin metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process + +[Term] +id: GO:0045575 +name: basophil activation +namespace: biological_process +def: "The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors." [GOC:mgi_curators, ISBN:0781735149] +xref: Wikipedia:Basophil_activation +is_a: GO:0036230 ! granulocyte activation + +[Term] +id: GO:0045576 +name: mast cell activation +namespace: biological_process +def: "The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors." [GOC:mgi_curators, ISBN:0781735149] +is_a: GO:0002274 ! myeloid leukocyte activation + +[Term] +id: GO:0045577 +name: regulation of B cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of B cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of B cell development" RELATED [GOC:add] +synonym: "regulation of B lymphocyte differentiation" EXACT [] +synonym: "regulation of B-cell differentiation" EXACT [] +synonym: "regulation of B-lymphocyte differentiation" EXACT [] +is_a: GO:0045619 ! regulation of lymphocyte differentiation +is_a: GO:0050864 ! regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030183 ! B cell differentiation +relationship: regulates GO:0030183 ! B cell differentiation + +[Term] +id: GO:0045578 +name: negative regulation of B cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of B cell differentiation" EXACT [] +synonym: "down-regulation of B cell differentiation" EXACT [] +synonym: "downregulation of B cell differentiation" EXACT [] +synonym: "inhibition of B cell differentiation" NARROW [] +synonym: "negative regulation of B cell development" RELATED [GOC:add] +synonym: "negative regulation of B lymphocyte differentiation" EXACT [] +synonym: "negative regulation of B-cell differentiation" EXACT [] +synonym: "negative regulation of B-lymphocyte differentiation" EXACT [] +is_a: GO:0045577 ! regulation of B cell differentiation +is_a: GO:0045620 ! negative regulation of lymphocyte differentiation +is_a: GO:0050869 ! negative regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030183 ! B cell differentiation +relationship: negatively_regulates GO:0030183 ! B cell differentiation + +[Term] +id: GO:0045579 +name: positive regulation of B cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of B cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of B cell differentiation" NARROW [] +synonym: "positive regulation of B cell development" RELATED [GOC:add] +synonym: "positive regulation of B lymphocyte differentiation" EXACT [] +synonym: "positive regulation of B-cell differentiation" EXACT [] +synonym: "positive regulation of B-lymphocyte differentiation" EXACT [] +synonym: "stimulation of B cell differentiation" NARROW [] +synonym: "up regulation of B cell differentiation" EXACT [] +synonym: "up-regulation of B cell differentiation" EXACT [] +synonym: "upregulation of B cell differentiation" EXACT [] +is_a: GO:0045577 ! regulation of B cell differentiation +is_a: GO:0045621 ! positive regulation of lymphocyte differentiation +is_a: GO:0050871 ! positive regulation of B cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030183 ! B cell differentiation +relationship: positively_regulates GO:0030183 ! B cell differentiation + +[Term] +id: GO:0045580 +name: regulation of T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of T cell development" RELATED [GOC:add] +synonym: "regulation of T lymphocyte differentiation" EXACT [] +synonym: "regulation of T-cell differentiation" EXACT [] +synonym: "regulation of T-lymphocyte differentiation" EXACT [] +is_a: GO:0045619 ! regulation of lymphocyte differentiation +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030217 ! T cell differentiation +relationship: regulates GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045581 +name: negative regulation of T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of T cell differentiation" EXACT [] +synonym: "down-regulation of T cell differentiation" EXACT [] +synonym: "downregulation of T cell differentiation" EXACT [] +synonym: "inhibition of T cell differentiation" NARROW [] +synonym: "negative regulation of T cell development" RELATED [GOC:add] +synonym: "negative regulation of T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of T-cell differentiation" EXACT [] +synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:0045620 ! negative regulation of lymphocyte differentiation +is_a: GO:0050868 ! negative regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030217 ! T cell differentiation +relationship: negatively_regulates GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045582 +name: positive regulation of T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of T cell differentiation" NARROW [] +synonym: "positive regulation of T cell development" RELATED [GOC:add] +synonym: "positive regulation of T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of T-cell differentiation" EXACT [] +synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of T cell differentiation" NARROW [] +synonym: "up regulation of T cell differentiation" EXACT [] +synonym: "up-regulation of T cell differentiation" EXACT [] +synonym: "upregulation of T cell differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:0045621 ! positive regulation of lymphocyte differentiation +is_a: GO:0050870 ! positive regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030217 ! T cell differentiation +relationship: positively_regulates GO:0030217 ! T cell differentiation + +[Term] +id: GO:0045583 +name: regulation of cytotoxic T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of cytotoxic T cell development" RELATED [GOC:add] +synonym: "regulation of cytotoxic T lymphocyte differentiation" EXACT [] +synonym: "regulation of cytotoxic T-cell differentiation" EXACT [] +synonym: "regulation of cytotoxic T-lymphocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045065 ! cytotoxic T cell differentiation +relationship: regulates GO:0045065 ! cytotoxic T cell differentiation + +[Term] +id: GO:0045584 +name: negative regulation of cytotoxic T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of cytotoxic T cell differentiation" EXACT [] +synonym: "down-regulation of cytotoxic T cell differentiation" EXACT [] +synonym: "downregulation of cytotoxic T cell differentiation" EXACT [] +synonym: "inhibition of cytotoxic T cell differentiation" NARROW [] +synonym: "negative regulation of cytotoxic T cell development" RELATED [GOC:add] +synonym: "negative regulation of cytotoxic T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of cytotoxic T-cell differentiation" EXACT [] +synonym: "negative regulation of cytotoxic T-lymphocyte differentiation" EXACT [] +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:0045583 ! regulation of cytotoxic T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045065 ! cytotoxic T cell differentiation +relationship: negatively_regulates GO:0045065 ! cytotoxic T cell differentiation + +[Term] +id: GO:0045585 +name: positive regulation of cytotoxic T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of cytotoxic T cell differentiation" NARROW [] +synonym: "positive regulation of cytotoxic T cell development" RELATED [GOC:add] +synonym: "positive regulation of cytotoxic T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of cytotoxic T-cell differentiation" EXACT [] +synonym: "positive regulation of cytotoxic T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of cytotoxic T cell differentiation" NARROW [] +synonym: "up regulation of cytotoxic T cell differentiation" EXACT [] +synonym: "up-regulation of cytotoxic T cell differentiation" EXACT [] +synonym: "upregulation of cytotoxic T cell differentiation" EXACT [] +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:0045583 ! regulation of cytotoxic T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045065 ! cytotoxic T cell differentiation +relationship: positively_regulates GO:0045065 ! cytotoxic T cell differentiation + +[Term] +id: GO:0045586 +name: regulation of gamma-delta T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of gamma-delta T cell development" RELATED [GOC:add] +synonym: "regulation of gamma-delta T lymphocyte differentiation" EXACT [] +synonym: "regulation of gamma-delta T-cell differentiation" EXACT [] +synonym: "regulation of gamma-delta T-lymphocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:0046643 ! regulation of gamma-delta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042492 ! gamma-delta T cell differentiation +relationship: regulates GO:0042492 ! gamma-delta T cell differentiation + +[Term] +id: GO:0045587 +name: negative regulation of gamma-delta T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of gamma-delta T cell differentiation" EXACT [] +synonym: "down-regulation of gamma-delta T cell differentiation" EXACT [] +synonym: "downregulation of gamma-delta T cell differentiation" EXACT [] +synonym: "inhibition of gamma-delta T cell differentiation" NARROW [] +synonym: "negative regulation of gamma-delta T cell development" RELATED [GOC:add] +synonym: "negative regulation of gamma-delta T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of gamma-delta T-cell differentiation" EXACT [] +synonym: "negative regulation of gamma-delta T-lymphocyte differentiation" EXACT [] +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:0045586 ! regulation of gamma-delta T cell differentiation +is_a: GO:0046644 ! negative regulation of gamma-delta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042492 ! gamma-delta T cell differentiation +relationship: negatively_regulates GO:0042492 ! gamma-delta T cell differentiation + +[Term] +id: GO:0045588 +name: positive regulation of gamma-delta T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of gamma-delta T cell differentiation" NARROW [] +synonym: "positive regulation of gamma-delta T cell development" RELATED [GOC:add] +synonym: "positive regulation of gamma-delta T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of gamma-delta T-cell differentiation" EXACT [] +synonym: "positive regulation of gamma-delta T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of gamma-delta T cell differentiation" NARROW [] +synonym: "up regulation of gamma-delta T cell differentiation" EXACT [] +synonym: "up-regulation of gamma-delta T cell differentiation" EXACT [] +synonym: "upregulation of gamma-delta T cell differentiation" EXACT [] +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:0045586 ! regulation of gamma-delta T cell differentiation +is_a: GO:0046645 ! positive regulation of gamma-delta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042492 ! gamma-delta T cell differentiation +relationship: positively_regulates GO:0042492 ! gamma-delta T cell differentiation + +[Term] +id: GO:0045589 +name: regulation of regulatory T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of regulatory T cell development" RELATED [GOC:add] +synonym: "regulation of regulatory T lymphocyte differentiation" EXACT [] +synonym: "regulation of regulatory T-cell differentiation" EXACT [] +synonym: "regulation of regulatory T-lymphocyte differentiation" EXACT [] +synonym: "regulation of suppressor T cell differentiation" EXACT [] +synonym: "regulation of suppressor T lymphocyte differentiation" EXACT [] +synonym: "regulation of suppressor T-cell differentiation" EXACT [] +synonym: "regulation of suppressor T-lymphocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045066 ! regulatory T cell differentiation +relationship: regulates GO:0045066 ! regulatory T cell differentiation + +[Term] +id: GO:0045590 +name: negative regulation of regulatory T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of regulatory T cell differentiation" EXACT [] +synonym: "down-regulation of regulatory T cell differentiation" EXACT [] +synonym: "downregulation of regulatory T cell differentiation" EXACT [] +synonym: "inhibition of regulatory T cell differentiation" NARROW [] +synonym: "negative regulation of regulatory T cell development" RELATED [GOC:add] +synonym: "negative regulation of regulatory T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of regulatory T-cell differentiation" EXACT [] +synonym: "negative regulation of regulatory T-lymphocyte differentiation" EXACT [] +synonym: "negative regulation of suppressor T cell differentiation" EXACT [] +synonym: "negative regulation of suppressor T-cell differentiation" EXACT [] +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:0045589 ! regulation of regulatory T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045066 ! regulatory T cell differentiation +relationship: negatively_regulates GO:0045066 ! regulatory T cell differentiation + +[Term] +id: GO:0045591 +name: positive regulation of regulatory T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells." [ISBN:0781735149] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of regulatory T cell differentiation" NARROW [] +synonym: "positive regulation of regulatory T cell development" RELATED [GOC:add] +synonym: "positive regulation of regulatory T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of regulatory T-cell differentiation" EXACT [] +synonym: "positive regulation of regulatory T-lymphocyte differentiation" EXACT [] +synonym: "positive regulation of suppressor T cell differentiation" EXACT [] +synonym: "positive regulation of suppressor T-cell differentiation" EXACT [] +synonym: "stimulation of regulatory T cell differentiation" NARROW [] +synonym: "up regulation of regulatory T cell differentiation" EXACT [] +synonym: "up-regulation of regulatory T cell differentiation" EXACT [] +synonym: "upregulation of regulatory T cell differentiation" EXACT [] +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:0045589 ! regulation of regulatory T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045066 ! regulatory T cell differentiation +relationship: positively_regulates GO:0045066 ! regulatory T cell differentiation + +[Term] +id: GO:0045592 +name: regulation of cumulus cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] +synonym: "regulation of ovarian cumulus cell differentiation" EXACT [] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:1905879 ! regulation of oogenesis +is_a: GO:2000387 ! regulation of antral ovarian follicle growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001549 ! cumulus cell differentiation +relationship: regulates GO:0001549 ! cumulus cell differentiation + +[Term] +id: GO:0045593 +name: negative regulation of cumulus cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] +synonym: "down regulation of cumulus cell differentiation" EXACT [] +synonym: "down-regulation of cumulus cell differentiation" EXACT [] +synonym: "downregulation of cumulus cell differentiation" EXACT [] +synonym: "inhibition of cumulus cell differentiation" NARROW [] +synonym: "negative regulation of ovarian cumulus cell differentiation" EXACT [] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0045592 ! regulation of cumulus cell differentiation +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1905880 ! negative regulation of oogenesis +is_a: GO:2000355 ! negative regulation of ovarian follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001549 ! cumulus cell differentiation +relationship: negatively_regulates GO:0001549 ! cumulus cell differentiation + +[Term] +id: GO:0045594 +name: positive regulation of cumulus cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] +synonym: "activation of cumulus cell differentiation" NARROW [] +synonym: "positive regulation of ovarian cumulus cell differentiation" EXACT [] +synonym: "stimulation of cumulus cell differentiation" NARROW [] +synonym: "up regulation of cumulus cell differentiation" EXACT [] +synonym: "up-regulation of cumulus cell differentiation" EXACT [] +synonym: "upregulation of cumulus cell differentiation" EXACT [] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0045592 ! regulation of cumulus cell differentiation +is_a: GO:1905881 ! positive regulation of oogenesis +is_a: GO:2000388 ! positive regulation of antral ovarian follicle growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001549 ! cumulus cell differentiation +relationship: positively_regulates GO:0001549 ! cumulus cell differentiation + +[Term] +id: GO:0045595 +name: regulation of cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030154 ! cell differentiation +relationship: regulates GO:0030154 ! cell differentiation + +[Term] +id: GO:0045596 +name: negative regulation of cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] +synonym: "down regulation of cell differentiation" EXACT [] +synonym: "down-regulation of cell differentiation" EXACT [] +synonym: "downregulation of cell differentiation" EXACT [] +synonym: "inhibition of cell differentiation" NARROW [] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030154 ! cell differentiation +relationship: negatively_regulates GO:0030154 ! cell differentiation + +[Term] +id: GO:0045597 +name: positive regulation of cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] +synonym: "activation of cell differentiation" NARROW [] +synonym: "stimulation of cell differentiation" NARROW [] +synonym: "up regulation of cell differentiation" EXACT [] +synonym: "up-regulation of cell differentiation" EXACT [] +synonym: "upregulation of cell differentiation" EXACT [] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030154 ! cell differentiation +relationship: positively_regulates GO:0030154 ! cell differentiation + +[Term] +id: GO:0045598 +name: regulation of fat cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] +synonym: "regulation of adipocyte cell differentiation" EXACT [] +synonym: "regulation of adipocyte differentiation" EXACT [] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045444 ! fat cell differentiation +relationship: regulates GO:0045444 ! fat cell differentiation + +[Term] +id: GO:0045599 +name: negative regulation of fat cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] +synonym: "down regulation of fat cell differentiation" EXACT [] +synonym: "down-regulation of fat cell differentiation" EXACT [] +synonym: "downregulation of fat cell differentiation" EXACT [] +synonym: "inhibition of fat cell differentiation" NARROW [] +synonym: "negative regulation of adipocyte cell differentiation" EXACT [] +synonym: "negative regulation of adipocyte differentiation" EXACT [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045598 ! regulation of fat cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045444 ! fat cell differentiation +relationship: negatively_regulates GO:0045444 ! fat cell differentiation + +[Term] +id: GO:0045600 +name: positive regulation of fat cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] +synonym: "activation of fat cell differentiation" NARROW [] +synonym: "positive regulation of adipocyte cell differentiation" EXACT [] +synonym: "positive regulation of adipocyte differentiation" EXACT [] +synonym: "stimulation of fat cell differentiation" NARROW [] +synonym: "up regulation of fat cell differentiation" EXACT [] +synonym: "up-regulation of fat cell differentiation" EXACT [] +synonym: "upregulation of fat cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045598 ! regulation of fat cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045444 ! fat cell differentiation +relationship: positively_regulates GO:0045444 ! fat cell differentiation + +[Term] +id: GO:0045601 +name: regulation of endothelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045446 ! endothelial cell differentiation +relationship: regulates GO:0045446 ! endothelial cell differentiation + +[Term] +id: GO:0045602 +name: negative regulation of endothelial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] +synonym: "down regulation of endothelial cell differentiation" EXACT [] +synonym: "down-regulation of endothelial cell differentiation" EXACT [] +synonym: "downregulation of endothelial cell differentiation" EXACT [] +synonym: "inhibition of endothelial cell differentiation" NARROW [] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0045601 ! regulation of endothelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045446 ! endothelial cell differentiation +relationship: negatively_regulates GO:0045446 ! endothelial cell differentiation + +[Term] +id: GO:0045603 +name: positive regulation of endothelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] +synonym: "activation of endothelial cell differentiation" NARROW [] +synonym: "stimulation of endothelial cell differentiation" NARROW [] +synonym: "up regulation of endothelial cell differentiation" EXACT [] +synonym: "up-regulation of endothelial cell differentiation" EXACT [] +synonym: "upregulation of endothelial cell differentiation" EXACT [] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0045601 ! regulation of endothelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045446 ! endothelial cell differentiation +relationship: positively_regulates GO:0045446 ! endothelial cell differentiation + +[Term] +id: GO:0045604 +name: regulation of epidermal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] +synonym: "regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0045682 ! regulation of epidermis development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009913 ! epidermal cell differentiation +relationship: regulates GO:0009913 ! epidermal cell differentiation + +[Term] +id: GO:0045605 +name: negative regulation of epidermal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] +synonym: "down regulation of epidermal cell differentiation" EXACT [] +synonym: "down-regulation of epidermal cell differentiation" EXACT [] +synonym: "downregulation of epidermal cell differentiation" EXACT [] +synonym: "inhibition of epidermal cell differentiation" NARROW [] +synonym: "negative regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0045604 ! regulation of epidermal cell differentiation +is_a: GO:0045683 ! negative regulation of epidermis development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009913 ! epidermal cell differentiation +relationship: negatively_regulates GO:0009913 ! epidermal cell differentiation + +[Term] +id: GO:0045606 +name: positive regulation of epidermal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] +synonym: "activation of epidermal cell differentiation" NARROW [] +synonym: "positive regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] +synonym: "stimulation of epidermal cell differentiation" NARROW [] +synonym: "up regulation of epidermal cell differentiation" EXACT [] +synonym: "up-regulation of epidermal cell differentiation" EXACT [] +synonym: "upregulation of epidermal cell differentiation" EXACT [] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0045604 ! regulation of epidermal cell differentiation +is_a: GO:0045684 ! positive regulation of epidermis development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009913 ! epidermal cell differentiation +relationship: positively_regulates GO:0009913 ! epidermal cell differentiation + +[Term] +id: GO:0045607 +name: regulation of inner ear auditory receptor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] +synonym: "regulation of auditory hair cell differentiation" EXACT [] +synonym: "regulation of auditory receptor cell differentiation" RELATED [] +is_a: GO:0045604 ! regulation of epidermal cell differentiation +is_a: GO:2000980 ! regulation of inner ear receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042491 ! inner ear auditory receptor cell differentiation +relationship: regulates GO:0042491 ! inner ear auditory receptor cell differentiation + +[Term] +id: GO:0045608 +name: negative regulation of inner ear auditory receptor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] +synonym: "down regulation of auditory receptor cell differentiation" EXACT [] +synonym: "down-regulation of auditory receptor cell differentiation" EXACT [] +synonym: "downregulation of auditory receptor cell differentiation" EXACT [] +synonym: "inhibition of auditory receptor cell differentiation" NARROW [] +synonym: "negative regulation of auditory hair cell differentiation" EXACT [] +synonym: "negative regulation of auditory receptor cell differentiation" RELATED [] +is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation +is_a: GO:0045605 ! negative regulation of epidermal cell differentiation +is_a: GO:0045607 ! regulation of inner ear auditory receptor cell differentiation +is_a: GO:2000981 ! negative regulation of inner ear receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042491 ! inner ear auditory receptor cell differentiation +relationship: negatively_regulates GO:0042491 ! inner ear auditory receptor cell differentiation + +[Term] +id: GO:0045609 +name: positive regulation of inner ear auditory receptor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] +synonym: "activation of auditory receptor cell differentiation" NARROW [] +synonym: "positive regulation of auditory hair cell differentiation" EXACT [] +synonym: "positive regulation of auditory receptor cell differentiation" RELATED [] +synonym: "stimulation of auditory receptor cell differentiation" NARROW [] +synonym: "up regulation of auditory receptor cell differentiation" EXACT [] +synonym: "up-regulation of auditory receptor cell differentiation" EXACT [] +synonym: "upregulation of auditory receptor cell differentiation" EXACT [] +is_a: GO:0045606 ! positive regulation of epidermal cell differentiation +is_a: GO:0045607 ! regulation of inner ear auditory receptor cell differentiation +is_a: GO:1902913 ! positive regulation of neuroepithelial cell differentiation +is_a: GO:2000982 ! positive regulation of inner ear receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042491 ! inner ear auditory receptor cell differentiation +relationship: positively_regulates GO:0042491 ! inner ear auditory receptor cell differentiation + +[Term] +id: GO:0045610 +name: regulation of hemocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] +synonym: "regulation of arthropod blood cell differentiation" EXACT [] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042386 ! hemocyte differentiation +relationship: regulates GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0045611 +name: negative regulation of hemocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] +synonym: "down regulation of hemocyte differentiation" EXACT [] +synonym: "down-regulation of hemocyte differentiation" EXACT [] +synonym: "downregulation of hemocyte differentiation" EXACT [] +synonym: "inhibition of hemocyte differentiation" NARROW [] +synonym: "negative regulation of arthropod blood cell differentiation" EXACT [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045610 ! regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042386 ! hemocyte differentiation +relationship: negatively_regulates GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0045612 +name: positive regulation of hemocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] +synonym: "activation of hemocyte differentiation" NARROW [] +synonym: "positive regulation of arthropod blood cell differentiation" EXACT [] +synonym: "stimulation of hemocyte differentiation" NARROW [] +synonym: "up regulation of hemocyte differentiation" EXACT [] +synonym: "up-regulation of hemocyte differentiation" EXACT [] +synonym: "upregulation of hemocyte differentiation" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045610 ! regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042386 ! hemocyte differentiation +relationship: positively_regulates GO:0042386 ! hemocyte differentiation + +[Term] +id: GO:0045613 +name: regulation of plasmatocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] +is_a: GO:0045610 ! regulation of hemocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042387 ! plasmatocyte differentiation +relationship: regulates GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0045614 +name: negative regulation of plasmatocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] +synonym: "down regulation of plasmatocyte differentiation" EXACT [] +synonym: "down-regulation of plasmatocyte differentiation" EXACT [] +synonym: "downregulation of plasmatocyte differentiation" EXACT [] +synonym: "inhibition of plasmatocyte differentiation" NARROW [] +is_a: GO:0045611 ! negative regulation of hemocyte differentiation +is_a: GO:0045613 ! regulation of plasmatocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042387 ! plasmatocyte differentiation +relationship: negatively_regulates GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0045615 +name: positive regulation of plasmatocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] +synonym: "activation of plasmatocyte differentiation" NARROW [] +synonym: "stimulation of plasmatocyte differentiation" NARROW [] +synonym: "up regulation of plasmatocyte differentiation" EXACT [] +synonym: "up-regulation of plasmatocyte differentiation" EXACT [] +synonym: "upregulation of plasmatocyte differentiation" EXACT [] +is_a: GO:0045612 ! positive regulation of hemocyte differentiation +is_a: GO:0045613 ! regulation of plasmatocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042387 ! plasmatocyte differentiation +relationship: positively_regulates GO:0042387 ! plasmatocyte differentiation + +[Term] +id: GO:0045616 +name: regulation of keratinocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] +is_a: GO:0045604 ! regulation of epidermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030216 ! keratinocyte differentiation +relationship: regulates GO:0030216 ! keratinocyte differentiation + +[Term] +id: GO:0045617 +name: negative regulation of keratinocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] +synonym: "down regulation of keratinocyte differentiation" EXACT [] +synonym: "down-regulation of keratinocyte differentiation" EXACT [] +synonym: "downregulation of keratinocyte differentiation" EXACT [] +synonym: "inhibition of keratinocyte differentiation" NARROW [] +is_a: GO:0045605 ! negative regulation of epidermal cell differentiation +is_a: GO:0045616 ! regulation of keratinocyte differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030216 ! keratinocyte differentiation +relationship: negatively_regulates GO:0030216 ! keratinocyte differentiation + +[Term] +id: GO:0045618 +name: positive regulation of keratinocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] +synonym: "activation of keratinocyte differentiation" NARROW [] +synonym: "stimulation of keratinocyte differentiation" NARROW [] +synonym: "up regulation of keratinocyte differentiation" EXACT [] +synonym: "up-regulation of keratinocyte differentiation" EXACT [] +synonym: "upregulation of keratinocyte differentiation" EXACT [] +is_a: GO:0045606 ! positive regulation of epidermal cell differentiation +is_a: GO:0045616 ! regulation of keratinocyte differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030216 ! keratinocyte differentiation +relationship: positively_regulates GO:0030216 ! keratinocyte differentiation + +[Term] +id: GO:0045619 +name: regulation of lymphocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of lymphocyte development" RELATED [GOC:add] +is_a: GO:0051249 ! regulation of lymphocyte activation +is_a: GO:1902105 ! regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030098 ! lymphocyte differentiation +relationship: regulates GO:0030098 ! lymphocyte differentiation + +[Term] +id: GO:0045620 +name: negative regulation of lymphocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of lymphocyte differentiation" EXACT [] +synonym: "down-regulation of lymphocyte differentiation" EXACT [] +synonym: "downregulation of lymphocyte differentiation" EXACT [] +synonym: "inhibition of lymphocyte differentiation" NARROW [] +synonym: "negative regulation of lymphocyte development" RELATED [GOC:add] +is_a: GO:0045619 ! regulation of lymphocyte differentiation +is_a: GO:0051250 ! negative regulation of lymphocyte activation +is_a: GO:1902106 ! negative regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030098 ! lymphocyte differentiation +relationship: negatively_regulates GO:0030098 ! lymphocyte differentiation + +[Term] +id: GO:0045621 +name: positive regulation of lymphocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of lymphocyte differentiation" NARROW [] +synonym: "positive regulation of lymphocyte development" RELATED [GOC:add] +synonym: "stimulation of lymphocyte differentiation" NARROW [] +synonym: "up regulation of lymphocyte differentiation" EXACT [] +synonym: "up-regulation of lymphocyte differentiation" EXACT [] +synonym: "upregulation of lymphocyte differentiation" EXACT [] +is_a: GO:0045619 ! regulation of lymphocyte differentiation +is_a: GO:0051251 ! positive regulation of lymphocyte activation +is_a: GO:1902107 ! positive regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030098 ! lymphocyte differentiation +relationship: positively_regulates GO:0030098 ! lymphocyte differentiation + +[Term] +id: GO:0045622 +name: regulation of T-helper cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of T-helper cell development" RELATED [GOC:add] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0043370 ! regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042093 ! T-helper cell differentiation +relationship: regulates GO:0042093 ! T-helper cell differentiation + +[Term] +id: GO:0045623 +name: negative regulation of T-helper cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of T-helper cell differentiation" EXACT [] +synonym: "down-regulation of T-helper cell differentiation" EXACT [] +synonym: "downregulation of T-helper cell differentiation" EXACT [] +synonym: "inhibition of T-helper cell differentiation" NARROW [] +synonym: "negative regulation of T-helper cell development" RELATED [GOC:add] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0043371 ! negative regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045622 ! regulation of T-helper cell differentiation +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042093 ! T-helper cell differentiation +relationship: negatively_regulates GO:0042093 ! T-helper cell differentiation + +[Term] +id: GO:0045624 +name: positive regulation of T-helper cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of T-helper cell differentiation" NARROW [] +synonym: "positive regulation of T-helper cell development" RELATED [GOC:add] +synonym: "stimulation of T-helper cell differentiation" NARROW [] +synonym: "up regulation of T-helper cell differentiation" EXACT [] +synonym: "up-regulation of T-helper cell differentiation" EXACT [] +synonym: "upregulation of T-helper cell differentiation" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0043372 ! positive regulation of CD4-positive, alpha-beta T cell differentiation +is_a: GO:0045622 ! regulation of T-helper cell differentiation +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042093 ! T-helper cell differentiation +relationship: positively_regulates GO:0042093 ! T-helper cell differentiation + +[Term] +id: GO:0045625 +name: regulation of T-helper 1 cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of T-helper 1 cell development" RELATED [GOC:add] +is_a: GO:0002825 ! regulation of T-helper 1 type immune response +is_a: GO:0045622 ! regulation of T-helper cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045063 ! T-helper 1 cell differentiation +relationship: regulates GO:0045063 ! T-helper 1 cell differentiation + +[Term] +id: GO:0045626 +name: negative regulation of T-helper 1 cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of T-helper 1 cell differentiation" EXACT [] +synonym: "down-regulation of T-helper 1 cell differentiation" EXACT [] +synonym: "downregulation of T-helper 1 cell differentiation" EXACT [] +synonym: "inhibition of T-helper 1 cell differentiation" NARROW [] +synonym: "negative regulation of T-helper 1 cell development" RELATED [GOC:add] +is_a: GO:0002826 ! negative regulation of T-helper 1 type immune response +is_a: GO:0045623 ! negative regulation of T-helper cell differentiation +is_a: GO:0045625 ! regulation of T-helper 1 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045063 ! T-helper 1 cell differentiation +relationship: negatively_regulates GO:0045063 ! T-helper 1 cell differentiation + +[Term] +id: GO:0045627 +name: positive regulation of T-helper 1 cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of T-helper 1 cell differentiation" NARROW [] +synonym: "positive regulation of T-helper 1 cell development" RELATED [GOC:add] +synonym: "stimulation of T-helper 1 cell differentiation" NARROW [] +synonym: "up regulation of T-helper 1 cell differentiation" EXACT [] +synonym: "up-regulation of T-helper 1 cell differentiation" EXACT [] +synonym: "upregulation of T-helper 1 cell differentiation" EXACT [] +is_a: GO:0002827 ! positive regulation of T-helper 1 type immune response +is_a: GO:0045624 ! positive regulation of T-helper cell differentiation +is_a: GO:0045625 ! regulation of T-helper 1 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045063 ! T-helper 1 cell differentiation +relationship: positively_regulates GO:0045063 ! T-helper 1 cell differentiation + +[Term] +id: GO:0045628 +name: regulation of T-helper 2 cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of T-helper 2 cell development" RELATED [GOC:add] +is_a: GO:0002828 ! regulation of type 2 immune response +is_a: GO:0045622 ! regulation of T-helper cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045064 ! T-helper 2 cell differentiation +relationship: regulates GO:0045064 ! T-helper 2 cell differentiation + +[Term] +id: GO:0045629 +name: negative regulation of T-helper 2 cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of T-helper 2 cell differentiation" EXACT [] +synonym: "down-regulation of T-helper 2 cell differentiation" EXACT [] +synonym: "downregulation of T-helper 2 cell differentiation" EXACT [] +synonym: "inhibition of T-helper 2 cell differentiation" NARROW [] +synonym: "negative regulation of T-helper 2 cell development" RELATED [GOC:add] +is_a: GO:0002829 ! negative regulation of type 2 immune response +is_a: GO:0045623 ! negative regulation of T-helper cell differentiation +is_a: GO:0045628 ! regulation of T-helper 2 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045064 ! T-helper 2 cell differentiation +relationship: negatively_regulates GO:0045064 ! T-helper 2 cell differentiation + +[Term] +id: GO:0045630 +name: positive regulation of T-helper 2 cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of T-helper 2 cell differentiation" NARROW [] +synonym: "positive regulation of T-helper 2 cell development" RELATED [GOC:add] +synonym: "stimulation of T-helper 2 cell differentiation" NARROW [] +synonym: "up regulation of T-helper 2 cell differentiation" EXACT [] +synonym: "up-regulation of T-helper 2 cell differentiation" EXACT [] +synonym: "upregulation of T-helper 2 cell differentiation" EXACT [] +is_a: GO:0002830 ! positive regulation of type 2 immune response +is_a: GO:0045624 ! positive regulation of T-helper cell differentiation +is_a: GO:0045628 ! regulation of T-helper 2 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045064 ! T-helper 2 cell differentiation +relationship: positively_regulates GO:0045064 ! T-helper 2 cell differentiation + +[Term] +id: GO:0045631 +name: regulation of mechanoreceptor differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042490 ! mechanoreceptor differentiation +relationship: regulates GO:0042490 ! mechanoreceptor differentiation + +[Term] +id: GO:0045632 +name: negative regulation of mechanoreceptor differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] +synonym: "down regulation of mechanoreceptor differentiation" EXACT [] +synonym: "down-regulation of mechanoreceptor differentiation" EXACT [] +synonym: "downregulation of mechanoreceptor differentiation" EXACT [] +synonym: "inhibition of mechanoreceptor differentiation" NARROW [] +is_a: GO:0045631 ! regulation of mechanoreceptor differentiation +is_a: GO:0045665 ! negative regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042490 ! mechanoreceptor differentiation +relationship: negatively_regulates GO:0042490 ! mechanoreceptor differentiation + +[Term] +id: GO:0045633 +name: positive regulation of mechanoreceptor differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] +synonym: "activation of mechanoreceptor differentiation" NARROW [] +synonym: "stimulation of mechanoreceptor differentiation" NARROW [] +synonym: "up regulation of mechanoreceptor differentiation" EXACT [] +synonym: "up-regulation of mechanoreceptor differentiation" EXACT [] +synonym: "upregulation of mechanoreceptor differentiation" EXACT [] +is_a: GO:0045631 ! regulation of mechanoreceptor differentiation +is_a: GO:0045666 ! positive regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042490 ! mechanoreceptor differentiation +relationship: positively_regulates GO:0042490 ! mechanoreceptor differentiation + +[Term] +id: GO:0045634 +name: regulation of melanocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] +synonym: "regulation of melanophore differentiation" EXACT [] +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030318 ! melanocyte differentiation +relationship: regulates GO:0030318 ! melanocyte differentiation + +[Term] +id: GO:0045635 +name: negative regulation of melanocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] +synonym: "down regulation of melanocyte differentiation" EXACT [] +synonym: "down-regulation of melanocyte differentiation" EXACT [] +synonym: "downregulation of melanocyte differentiation" EXACT [] +synonym: "inhibition of melanocyte differentiation" NARROW [] +synonym: "negative regulation of melanophore differentiation" EXACT [] +is_a: GO:0045634 ! regulation of melanocyte differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030318 ! melanocyte differentiation +relationship: negatively_regulates GO:0030318 ! melanocyte differentiation + +[Term] +id: GO:0045636 +name: positive regulation of melanocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] +synonym: "activation of melanocyte differentiation" NARROW [] +synonym: "positive regulation of melanophore differentiation" EXACT [] +synonym: "stimulation of melanocyte differentiation" NARROW [] +synonym: "up regulation of melanocyte differentiation" EXACT [] +synonym: "up-regulation of melanocyte differentiation" EXACT [] +synonym: "upregulation of melanocyte differentiation" EXACT [] +is_a: GO:0045634 ! regulation of melanocyte differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030318 ! melanocyte differentiation +relationship: positively_regulates GO:0030318 ! melanocyte differentiation + +[Term] +id: GO:0045637 +name: regulation of myeloid cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030099 ! myeloid cell differentiation +relationship: regulates GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0045638 +name: negative regulation of myeloid cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] +synonym: "down regulation of myeloid cell differentiation" EXACT [] +synonym: "down-regulation of myeloid cell differentiation" EXACT [] +synonym: "downregulation of myeloid cell differentiation" EXACT [] +synonym: "inhibition of myeloid cell differentiation" NARROW [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045637 ! regulation of myeloid cell differentiation +is_a: GO:1903707 ! negative regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030099 ! myeloid cell differentiation +relationship: negatively_regulates GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0045639 +name: positive regulation of myeloid cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] +synonym: "activation of myeloid cell differentiation" NARROW [] +synonym: "stimulation of myeloid cell differentiation" NARROW [] +synonym: "up regulation of myeloid cell differentiation" EXACT [] +synonym: "up-regulation of myeloid cell differentiation" EXACT [] +synonym: "upregulation of myeloid cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045637 ! regulation of myeloid cell differentiation +is_a: GO:1903708 ! positive regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030099 ! myeloid cell differentiation +relationship: positively_regulates GO:0030099 ! myeloid cell differentiation + +[Term] +id: GO:0045640 +name: regulation of basophil differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of basophil differentiation." [GOC:go_curators] +is_a: GO:0030852 ! regulation of granulocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030221 ! basophil differentiation +relationship: regulates GO:0030221 ! basophil differentiation + +[Term] +id: GO:0045641 +name: negative regulation of basophil differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation." [GOC:go_curators] +synonym: "down regulation of basophil differentiation" EXACT [] +synonym: "down-regulation of basophil differentiation" EXACT [] +synonym: "downregulation of basophil differentiation" EXACT [] +synonym: "inhibition of basophil differentiation" NARROW [] +is_a: GO:0030853 ! negative regulation of granulocyte differentiation +is_a: GO:0045640 ! regulation of basophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030221 ! basophil differentiation +relationship: negatively_regulates GO:0030221 ! basophil differentiation + +[Term] +id: GO:0045642 +name: positive regulation of basophil differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of basophil differentiation." [GOC:go_curators] +synonym: "activation of basophil differentiation" NARROW [] +synonym: "stimulation of basophil differentiation" NARROW [] +synonym: "up regulation of basophil differentiation" EXACT [] +synonym: "up-regulation of basophil differentiation" EXACT [] +synonym: "upregulation of basophil differentiation" EXACT [] +is_a: GO:0030854 ! positive regulation of granulocyte differentiation +is_a: GO:0045640 ! regulation of basophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030221 ! basophil differentiation +relationship: positively_regulates GO:0030221 ! basophil differentiation + +[Term] +id: GO:0045643 +name: regulation of eosinophil differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] +is_a: GO:0030852 ! regulation of granulocyte differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030222 ! eosinophil differentiation +relationship: regulates GO:0030222 ! eosinophil differentiation + +[Term] +id: GO:0045644 +name: negative regulation of eosinophil differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] +synonym: "down regulation of eosinophil differentiation" EXACT [] +synonym: "down-regulation of eosinophil differentiation" EXACT [] +synonym: "downregulation of eosinophil differentiation" EXACT [] +synonym: "inhibition of eosinophil differentiation" NARROW [] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030853 ! negative regulation of granulocyte differentiation +is_a: GO:0045643 ! regulation of eosinophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030222 ! eosinophil differentiation +relationship: negatively_regulates GO:0030222 ! eosinophil differentiation + +[Term] +id: GO:0045645 +name: positive regulation of eosinophil differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] +synonym: "activation of eosinophil differentiation" NARROW [] +synonym: "stimulation of eosinophil differentiation" NARROW [] +synonym: "up regulation of eosinophil differentiation" EXACT [] +synonym: "up-regulation of eosinophil differentiation" EXACT [] +synonym: "upregulation of eosinophil differentiation" EXACT [] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030854 ! positive regulation of granulocyte differentiation +is_a: GO:0045643 ! regulation of eosinophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030222 ! eosinophil differentiation +relationship: positively_regulates GO:0030222 ! eosinophil differentiation + +[Term] +id: GO:0045646 +name: regulation of erythrocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] +synonym: "regulation of RBC differentiation" EXACT [CL:0000232] +synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0045637 ! regulation of myeloid cell differentiation +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030218 ! erythrocyte differentiation +relationship: regulates GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0045647 +name: negative regulation of erythrocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] +synonym: "down regulation of erythrocyte differentiation" EXACT [] +synonym: "down-regulation of erythrocyte differentiation" EXACT [] +synonym: "downregulation of erythrocyte differentiation" EXACT [] +synonym: "inhibition of erythrocyte differentiation" NARROW [] +synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232] +synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0045638 ! negative regulation of myeloid cell differentiation +is_a: GO:0045646 ! regulation of erythrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030218 ! erythrocyte differentiation +relationship: negatively_regulates GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0045648 +name: positive regulation of erythrocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] +synonym: "activation of erythrocyte differentiation" NARROW [] +synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232] +synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232] +synonym: "stimulation of erythrocyte differentiation" NARROW [] +synonym: "up regulation of erythrocyte differentiation" EXACT [] +synonym: "up-regulation of erythrocyte differentiation" EXACT [] +synonym: "upregulation of erythrocyte differentiation" EXACT [] +is_a: GO:0045639 ! positive regulation of myeloid cell differentiation +is_a: GO:0045646 ! regulation of erythrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030218 ! erythrocyte differentiation +relationship: positively_regulates GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0045649 +name: regulation of macrophage differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030225 ! macrophage differentiation +relationship: regulates GO:0030225 ! macrophage differentiation + +[Term] +id: GO:0045650 +name: negative regulation of macrophage differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] +synonym: "down regulation of macrophage differentiation" EXACT [] +synonym: "down-regulation of macrophage differentiation" EXACT [] +synonym: "downregulation of macrophage differentiation" EXACT [] +synonym: "inhibition of macrophage differentiation" NARROW [] +is_a: GO:0002762 ! negative regulation of myeloid leukocyte differentiation +is_a: GO:0045649 ! regulation of macrophage differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030225 ! macrophage differentiation +relationship: negatively_regulates GO:0030225 ! macrophage differentiation + +[Term] +id: GO:0045651 +name: positive regulation of macrophage differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] +synonym: "activation of macrophage differentiation" NARROW [] +synonym: "stimulation of macrophage differentiation" NARROW [] +synonym: "up regulation of macrophage differentiation" EXACT [] +synonym: "up-regulation of macrophage differentiation" EXACT [] +synonym: "upregulation of macrophage differentiation" EXACT [] +is_a: GO:0002763 ! positive regulation of myeloid leukocyte differentiation +is_a: GO:0045649 ! regulation of macrophage differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030225 ! macrophage differentiation +relationship: positively_regulates GO:0030225 ! macrophage differentiation + +[Term] +id: GO:0045652 +name: regulation of megakaryocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] +is_a: GO:0045637 ! regulation of myeloid cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030219 ! megakaryocyte differentiation +relationship: regulates GO:0030219 ! megakaryocyte differentiation + +[Term] +id: GO:0045653 +name: negative regulation of megakaryocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] +synonym: "down regulation of megakaryocyte differentiation" EXACT [] +synonym: "down-regulation of megakaryocyte differentiation" EXACT [] +synonym: "downregulation of megakaryocyte differentiation" EXACT [] +synonym: "inhibition of megakaryocyte differentiation" NARROW [] +is_a: GO:0045638 ! negative regulation of myeloid cell differentiation +is_a: GO:0045652 ! regulation of megakaryocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030219 ! megakaryocyte differentiation +relationship: negatively_regulates GO:0030219 ! megakaryocyte differentiation + +[Term] +id: GO:0045654 +name: positive regulation of megakaryocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] +synonym: "activation of megakaryocyte differentiation" NARROW [] +synonym: "stimulation of megakaryocyte differentiation" NARROW [] +synonym: "up regulation of megakaryocyte differentiation" EXACT [] +synonym: "up-regulation of megakaryocyte differentiation" EXACT [] +synonym: "upregulation of megakaryocyte differentiation" EXACT [] +is_a: GO:0045639 ! positive regulation of myeloid cell differentiation +is_a: GO:0045652 ! regulation of megakaryocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030219 ! megakaryocyte differentiation +relationship: positively_regulates GO:0030219 ! megakaryocyte differentiation + +[Term] +id: GO:0045655 +name: regulation of monocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030224 ! monocyte differentiation +relationship: regulates GO:0030224 ! monocyte differentiation + +[Term] +id: GO:0045656 +name: negative regulation of monocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] +synonym: "down regulation of monocyte differentiation" EXACT [] +synonym: "down-regulation of monocyte differentiation" EXACT [] +synonym: "downregulation of monocyte differentiation" EXACT [] +synonym: "inhibition of monocyte differentiation" NARROW [] +is_a: GO:0002762 ! negative regulation of myeloid leukocyte differentiation +is_a: GO:0045655 ! regulation of monocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030224 ! monocyte differentiation +relationship: negatively_regulates GO:0030224 ! monocyte differentiation + +[Term] +id: GO:0045657 +name: positive regulation of monocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] +synonym: "activation of monocyte differentiation" NARROW [] +synonym: "stimulation of monocyte differentiation" NARROW [] +synonym: "up regulation of monocyte differentiation" EXACT [] +synonym: "up-regulation of monocyte differentiation" EXACT [] +synonym: "upregulation of monocyte differentiation" EXACT [] +is_a: GO:0002763 ! positive regulation of myeloid leukocyte differentiation +is_a: GO:0045655 ! regulation of monocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030224 ! monocyte differentiation +relationship: positively_regulates GO:0030224 ! monocyte differentiation + +[Term] +id: GO:0045658 +name: regulation of neutrophil differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] +is_a: GO:0030852 ! regulation of granulocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030223 ! neutrophil differentiation +relationship: regulates GO:0030223 ! neutrophil differentiation + +[Term] +id: GO:0045659 +name: negative regulation of neutrophil differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] +synonym: "down regulation of neutrophil differentiation" EXACT [] +synonym: "down-regulation of neutrophil differentiation" EXACT [] +synonym: "downregulation of neutrophil differentiation" EXACT [] +synonym: "inhibition of neutrophil differentiation" NARROW [] +is_a: GO:0030853 ! negative regulation of granulocyte differentiation +is_a: GO:0045658 ! regulation of neutrophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030223 ! neutrophil differentiation +relationship: negatively_regulates GO:0030223 ! neutrophil differentiation + +[Term] +id: GO:0045660 +name: positive regulation of neutrophil differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] +synonym: "activation of neutrophil differentiation" NARROW [] +synonym: "stimulation of neutrophil differentiation" NARROW [] +synonym: "up regulation of neutrophil differentiation" EXACT [] +synonym: "up-regulation of neutrophil differentiation" EXACT [] +synonym: "upregulation of neutrophil differentiation" EXACT [] +is_a: GO:0030854 ! positive regulation of granulocyte differentiation +is_a: GO:0045658 ! regulation of neutrophil differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030223 ! neutrophil differentiation +relationship: positively_regulates GO:0030223 ! neutrophil differentiation + +[Term] +id: GO:0045661 +name: regulation of myoblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045445 ! myoblast differentiation +relationship: regulates GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0045662 +name: negative regulation of myoblast differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] +synonym: "down regulation of myoblast differentiation" EXACT [] +synonym: "down-regulation of myoblast differentiation" EXACT [] +synonym: "downregulation of myoblast differentiation" EXACT [] +synonym: "inhibition of myoblast differentiation" NARROW [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045661 ! regulation of myoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045445 ! myoblast differentiation +relationship: negatively_regulates GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0045663 +name: positive regulation of myoblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] +synonym: "activation of myoblast differentiation" NARROW [] +synonym: "stimulation of myoblast differentiation" NARROW [] +synonym: "up regulation of myoblast differentiation" EXACT [] +synonym: "up-regulation of myoblast differentiation" EXACT [] +synonym: "upregulation of myoblast differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045661 ! regulation of myoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045445 ! myoblast differentiation +relationship: positively_regulates GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0045664 +name: regulation of neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] +is_a: GO:0050767 ! regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030182 ! neuron differentiation +relationship: regulates GO:0030182 ! neuron differentiation + +[Term] +id: GO:0045665 +name: negative regulation of neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] +synonym: "down regulation of neuron differentiation" EXACT [] +synonym: "down-regulation of neuron differentiation" EXACT [] +synonym: "downregulation of neuron differentiation" EXACT [] +synonym: "inhibition of neuron differentiation" NARROW [] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:0050768 ! negative regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030182 ! neuron differentiation +relationship: negatively_regulates GO:0030182 ! neuron differentiation + +[Term] +id: GO:0045666 +name: positive regulation of neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] +synonym: "activation of neuron differentiation" NARROW [] +synonym: "stimulation of neuron differentiation" NARROW [] +synonym: "up regulation of neuron differentiation" EXACT [] +synonym: "up-regulation of neuron differentiation" EXACT [] +synonym: "upregulation of neuron differentiation" EXACT [] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:0050769 ! positive regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030182 ! neuron differentiation +relationship: positively_regulates GO:0030182 ! neuron differentiation + +[Term] +id: GO:0045667 +name: regulation of osteoblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] +is_a: GO:0030278 ! regulation of ossification +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001649 ! osteoblast differentiation +relationship: regulates GO:0001649 ! osteoblast differentiation + +[Term] +id: GO:0045668 +name: negative regulation of osteoblast differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] +synonym: "down regulation of osteoblast differentiation" EXACT [] +synonym: "down-regulation of osteoblast differentiation" EXACT [] +synonym: "downregulation of osteoblast differentiation" EXACT [] +synonym: "inhibition of osteoblast differentiation" NARROW [] +is_a: GO:0030279 ! negative regulation of ossification +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045667 ! regulation of osteoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001649 ! osteoblast differentiation +relationship: negatively_regulates GO:0001649 ! osteoblast differentiation + +[Term] +id: GO:0045669 +name: positive regulation of osteoblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] +synonym: "activation of osteoblast differentiation" NARROW [] +synonym: "stimulation of osteoblast differentiation" NARROW [] +synonym: "up regulation of osteoblast differentiation" EXACT [] +synonym: "up-regulation of osteoblast differentiation" EXACT [] +synonym: "upregulation of osteoblast differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045667 ! regulation of osteoblast differentiation +is_a: GO:0045778 ! positive regulation of ossification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001649 ! osteoblast differentiation +relationship: positively_regulates GO:0001649 ! osteoblast differentiation + +[Term] +id: GO:0045670 +name: regulation of osteoclast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030316 ! osteoclast differentiation +relationship: regulates GO:0030316 ! osteoclast differentiation + +[Term] +id: GO:0045671 +name: negative regulation of osteoclast differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] +synonym: "down regulation of osteoclast differentiation" EXACT [] +synonym: "down-regulation of osteoclast differentiation" EXACT [] +synonym: "downregulation of osteoclast differentiation" EXACT [] +synonym: "inhibition of osteoclast differentiation" NARROW [] +is_a: GO:0002762 ! negative regulation of myeloid leukocyte differentiation +is_a: GO:0045670 ! regulation of osteoclast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030316 ! osteoclast differentiation +relationship: negatively_regulates GO:0030316 ! osteoclast differentiation + +[Term] +id: GO:0045672 +name: positive regulation of osteoclast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] +synonym: "activation of osteoclast differentiation" NARROW [] +synonym: "stimulation of osteoclast differentiation" NARROW [] +synonym: "up regulation of osteoclast differentiation" EXACT [] +synonym: "up-regulation of osteoclast differentiation" EXACT [] +synonym: "upregulation of osteoclast differentiation" EXACT [] +is_a: GO:0002763 ! positive regulation of myeloid leukocyte differentiation +is_a: GO:0045670 ! regulation of osteoclast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030316 ! osteoclast differentiation +relationship: positively_regulates GO:0030316 ! osteoclast differentiation + +[Term] +id: GO:0045676 +name: regulation of R7 cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of R7 differentiation." [GOC:go_curators] +is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045466 ! R7 cell differentiation +relationship: regulates GO:0045466 ! R7 cell differentiation + +[Term] +id: GO:0045677 +name: negative regulation of R7 cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of R7 differentiation" EXACT [] +synonym: "down-regulation of R7 differentiation" EXACT [] +synonym: "downregulation of R7 differentiation" EXACT [] +synonym: "inhibition of R7 differentiation" NARROW [] +synonym: "negative regulation of R7 differentiation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0045676 ! regulation of R7 cell differentiation +is_a: GO:0110118 ! negative regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045466 ! R7 cell differentiation +relationship: negatively_regulates GO:0045466 ! R7 cell differentiation + +[Term] +id: GO:0045678 +name: positive regulation of R7 cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of R7 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of R7 differentiation" NARROW [] +synonym: "positive regulation of R7 differentiation" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of R7 differentiation" NARROW [] +synonym: "up regulation of R7 differentiation" EXACT [] +synonym: "up-regulation of R7 differentiation" EXACT [] +synonym: "upregulation of R7 differentiation" EXACT [] +is_a: GO:0045676 ! regulation of R7 cell differentiation +is_a: GO:0110117 ! positive regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045466 ! R7 cell differentiation +relationship: positively_regulates GO:0045466 ! R7 cell differentiation + +[Term] +id: GO:0045679 +name: regulation of R8 cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of R8 differentiation." [GOC:go_curators] +is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045465 ! R8 cell differentiation +relationship: regulates GO:0045465 ! R8 cell differentiation + +[Term] +id: GO:0045680 +name: negative regulation of R8 cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of R8 differentiation" EXACT [] +synonym: "down-regulation of R8 differentiation" EXACT [] +synonym: "downregulation of R8 differentiation" EXACT [] +synonym: "inhibition of R8 differentiation" NARROW [] +synonym: "negative regulation of R8 differentiation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0045679 ! regulation of R8 cell differentiation +is_a: GO:0110118 ! negative regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045465 ! R8 cell differentiation +relationship: negatively_regulates GO:0045465 ! R8 cell differentiation + +[Term] +id: GO:0045681 +name: positive regulation of R8 cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of R8 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of R8 differentiation" NARROW [] +synonym: "positive regulation of R8 differentiation" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of R8 differentiation" NARROW [] +synonym: "up regulation of R8 differentiation" EXACT [] +synonym: "up-regulation of R8 differentiation" EXACT [] +synonym: "upregulation of R8 differentiation" EXACT [] +is_a: GO:0045679 ! regulation of R8 cell differentiation +is_a: GO:0110117 ! positive regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045465 ! R8 cell differentiation +relationship: positively_regulates GO:0045465 ! R8 cell differentiation + +[Term] +id: GO:0045682 +name: regulation of epidermis development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators] +synonym: "regulation of epidermal development" EXACT [] +synonym: "regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008544 ! epidermis development +relationship: regulates GO:0008544 ! epidermis development + +[Term] +id: GO:0045683 +name: negative regulation of epidermis development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators] +synonym: "down regulation of epidermis development" EXACT [] +synonym: "down-regulation of epidermis development" EXACT [] +synonym: "downregulation of epidermis development" EXACT [] +synonym: "inhibition of epidermis development" NARROW [] +synonym: "negative regulation of epidermal development" EXACT [] +synonym: "negative regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0045682 ! regulation of epidermis development +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008544 ! epidermis development +relationship: negatively_regulates GO:0008544 ! epidermis development + +[Term] +id: GO:0045684 +name: positive regulation of epidermis development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators] +synonym: "activation of epidermis development" NARROW [] +synonym: "positive regulation of epidermal development" EXACT [] +synonym: "positive regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] +synonym: "stimulation of epidermis development" NARROW [] +synonym: "up regulation of epidermis development" EXACT [] +synonym: "up-regulation of epidermis development" EXACT [] +synonym: "upregulation of epidermis development" EXACT [] +is_a: GO:0045682 ! regulation of epidermis development +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008544 ! epidermis development +relationship: positively_regulates GO:0008544 ! epidermis development + +[Term] +id: GO:0045685 +name: regulation of glial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] +synonym: "regulation of glia cell differentiation" EXACT [] +synonym: "regulation of neuroglia differentiation" EXACT [] +is_a: GO:0014013 ! regulation of gliogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010001 ! glial cell differentiation +relationship: regulates GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0045686 +name: negative regulation of glial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] +synonym: "down regulation of glial cell differentiation" EXACT [] +synonym: "down-regulation of glial cell differentiation" EXACT [] +synonym: "downregulation of glial cell differentiation" EXACT [] +synonym: "inhibition of glial cell differentiation" NARROW [] +synonym: "negative regulation of glia cell differentiation" EXACT [] +synonym: "negative regulation of neuroglia differentiation" EXACT [] +is_a: GO:0014014 ! negative regulation of gliogenesis +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010001 ! glial cell differentiation +relationship: negatively_regulates GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0045687 +name: positive regulation of glial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] +synonym: "activation of glial cell differentiation" NARROW [] +synonym: "positive regulation of glia cell differentiation" EXACT [] +synonym: "positive regulation of neuroglia differentiation" EXACT [] +synonym: "stimulation of glial cell differentiation" NARROW [] +synonym: "up regulation of glial cell differentiation" EXACT [] +synonym: "up-regulation of glial cell differentiation" EXACT [] +synonym: "upregulation of glial cell differentiation" EXACT [] +is_a: GO:0014015 ! positive regulation of gliogenesis +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010001 ! glial cell differentiation +relationship: positively_regulates GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0045688 +name: regulation of antipodal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009557 ! antipodal cell differentiation +relationship: regulates GO:0009557 ! antipodal cell differentiation + +[Term] +id: GO:0045689 +name: negative regulation of antipodal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "down regulation of antipodal cell differentiation" EXACT [] +synonym: "down-regulation of antipodal cell differentiation" EXACT [] +synonym: "downregulation of antipodal cell differentiation" EXACT [] +synonym: "inhibition of antipodal cell differentiation" NARROW [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045688 ! regulation of antipodal cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009557 ! antipodal cell differentiation +relationship: negatively_regulates GO:0009557 ! antipodal cell differentiation + +[Term] +id: GO:0045690 +name: positive regulation of antipodal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "activation of antipodal cell differentiation" NARROW [] +synonym: "stimulation of antipodal cell differentiation" NARROW [] +synonym: "up regulation of antipodal cell differentiation" EXACT [] +synonym: "up-regulation of antipodal cell differentiation" EXACT [] +synonym: "upregulation of antipodal cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045688 ! regulation of antipodal cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009557 ! antipodal cell differentiation +relationship: positively_regulates GO:0009557 ! antipodal cell differentiation + +[Term] +id: GO:0045691 +name: regulation of embryo sac central cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "regulation of female gametophyte central cell differentiation" EXACT [] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009559 ! embryo sac central cell differentiation +relationship: regulates GO:0009559 ! embryo sac central cell differentiation + +[Term] +id: GO:0045692 +name: negative regulation of embryo sac central cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "down regulation of female gametophyte central cell differentiation" EXACT [] +synonym: "down-regulation of female gametophyte central cell differentiation" EXACT [] +synonym: "downregulation of female gametophyte central cell differentiation" EXACT [] +synonym: "inhibition of female gametophyte central cell differentiation" NARROW [] +synonym: "negative regulation of female gametophyte central cell differentiation" EXACT [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045691 ! regulation of embryo sac central cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009559 ! embryo sac central cell differentiation +relationship: negatively_regulates GO:0009559 ! embryo sac central cell differentiation + +[Term] +id: GO:0045693 +name: positive regulation of embryo sac central cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "activation of female gametophyte central cell differentiation" NARROW [] +synonym: "positive regulation of female gametophyte central cell differentiation" EXACT [] +synonym: "stimulation of female gametophyte central cell differentiation" NARROW [] +synonym: "up regulation of female gametophyte central cell differentiation" EXACT [] +synonym: "up-regulation of female gametophyte central cell differentiation" EXACT [] +synonym: "upregulation of female gametophyte central cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045691 ! regulation of embryo sac central cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009559 ! embryo sac central cell differentiation +relationship: positively_regulates GO:0009559 ! embryo sac central cell differentiation + +[Term] +id: GO:0045694 +name: regulation of embryo sac egg cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "regulation of female gametophyte egg cell differentiation" EXACT [] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009560 ! embryo sac egg cell differentiation +relationship: regulates GO:0009560 ! embryo sac egg cell differentiation + +[Term] +id: GO:0045695 +name: negative regulation of embryo sac egg cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "down regulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "down-regulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "downregulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "inhibition of female gametophyte egg cell differentiation" NARROW [] +synonym: "negative regulation of female gametophyte egg cell differentiation" EXACT [] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045694 ! regulation of embryo sac egg cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009560 ! embryo sac egg cell differentiation +relationship: negatively_regulates GO:0009560 ! embryo sac egg cell differentiation + +[Term] +id: GO:0045696 +name: positive regulation of embryo sac egg cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] +synonym: "activation of female gametophyte egg cell differentiation" NARROW [] +synonym: "positive regulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "stimulation of female gametophyte egg cell differentiation" NARROW [] +synonym: "up regulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "up-regulation of female gametophyte egg cell differentiation" EXACT [] +synonym: "upregulation of female gametophyte egg cell differentiation" EXACT [] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045694 ! regulation of embryo sac egg cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009560 ! embryo sac egg cell differentiation +relationship: positively_regulates GO:0009560 ! embryo sac egg cell differentiation + +[Term] +id: GO:0045697 +name: regulation of synergid differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] +synonym: "regulation of synergid cell differentiation" EXACT [] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009563 ! synergid differentiation +relationship: regulates GO:0009563 ! synergid differentiation + +[Term] +id: GO:0045698 +name: negative regulation of synergid differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] +synonym: "down regulation of synergid differentiation" EXACT [] +synonym: "down-regulation of synergid differentiation" EXACT [] +synonym: "downregulation of synergid differentiation" EXACT [] +synonym: "inhibition of synergid differentiation" NARROW [] +synonym: "negative regulation of synergid cell differentiation" EXACT [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045697 ! regulation of synergid differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009563 ! synergid differentiation +relationship: negatively_regulates GO:0009563 ! synergid differentiation + +[Term] +id: GO:0045699 +name: positive regulation of synergid differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] +synonym: "activation of synergid differentiation" NARROW [] +synonym: "positive regulation of synergid cell differentiation" EXACT [] +synonym: "stimulation of synergid differentiation" NARROW [] +synonym: "up regulation of synergid differentiation" EXACT [] +synonym: "up-regulation of synergid differentiation" EXACT [] +synonym: "upregulation of synergid differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0045697 ! regulation of synergid differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009563 ! synergid differentiation +relationship: positively_regulates GO:0009563 ! synergid differentiation + +[Term] +id: GO:0045700 +name: regulation of spermatid nuclear differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0060284 ! regulation of cell development +is_a: GO:1903353 ! regulation of nucleus organization +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007289 ! spermatid nucleus differentiation +relationship: regulates GO:0007289 ! spermatid nucleus differentiation + +[Term] +id: GO:0045701 +name: negative regulation of spermatid nuclear differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] +synonym: "down regulation of spermatid nuclear differentiation" EXACT [] +synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] +synonym: "downregulation of spermatid nuclear differentiation" EXACT [] +synonym: "inhibition of spermatid nuclear differentiation" NARROW [] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0045700 ! regulation of spermatid nuclear differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007289 ! spermatid nucleus differentiation +relationship: negatively_regulates GO:0007289 ! spermatid nucleus differentiation + +[Term] +id: GO:0045702 +name: positive regulation of spermatid nuclear differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] +synonym: "activation of spermatid nuclear differentiation" NARROW [] +synonym: "stimulation of spermatid nuclear differentiation" NARROW [] +synonym: "up regulation of spermatid nuclear differentiation" EXACT [] +synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] +synonym: "upregulation of spermatid nuclear differentiation" EXACT [] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0045700 ! regulation of spermatid nuclear differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007289 ! spermatid nucleus differentiation +relationship: positively_regulates GO:0007289 ! spermatid nucleus differentiation + +[Term] +id: GO:0045703 +name: ketoreductase activity +namespace: molecular_function +def: "Catalysis of the reduction of a ketone group to form the corresponding alcohol." [GOC:curators] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0045704 +name: regulation of salivary gland boundary specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of salivary gland determination." [GOC:go_curators, GOC:tb] +synonym: "regulation of salivary gland determination" EXACT [GOC:tb] +is_a: GO:0003156 ! regulation of animal organ formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007432 ! salivary gland boundary specification +relationship: regulates GO:0007432 ! salivary gland boundary specification + +[Term] +id: GO:0045705 +name: negative regulation of salivary gland boundary specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination." [GOC:go_curators, GOC:tb] +synonym: "down regulation of salivary gland determination" EXACT [] +synonym: "down-regulation of salivary gland determination" EXACT [] +synonym: "downregulation of salivary gland determination" EXACT [] +synonym: "inhibition of salivary gland determination" NARROW [] +synonym: "negative regulation of salivary gland determination" EXACT [GOC:tb] +is_a: GO:0045704 ! regulation of salivary gland boundary specification +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007432 ! salivary gland boundary specification +relationship: negatively_regulates GO:0007432 ! salivary gland boundary specification + +[Term] +id: GO:0045706 +name: positive regulation of salivary gland boundary specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of salivary gland determination." [GOC:go_curators, GOC:tb] +synonym: "activation of salivary gland determination" NARROW [] +synonym: "positive regulation of salivary gland determination" EXACT [GOC:tb] +synonym: "stimulation of salivary gland determination" NARROW [] +synonym: "up regulation of salivary gland determination" EXACT [] +synonym: "up-regulation of salivary gland determination" EXACT [] +synonym: "upregulation of salivary gland determination" EXACT [] +is_a: GO:0045704 ! regulation of salivary gland boundary specification +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007432 ! salivary gland boundary specification +relationship: positively_regulates GO:0007432 ! salivary gland boundary specification + +[Term] +id: GO:0045707 +name: regulation of adult salivary gland boundary specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism." [GOC:go_curators, GOC:tb] +synonym: "regulation of adult salivary gland determination" EXACT [GOC:tb] +is_a: GO:0045704 ! regulation of salivary gland boundary specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007434 ! adult salivary gland boundary specification +relationship: regulates GO:0007434 ! adult salivary gland boundary specification + +[Term] +id: GO:0045708 +name: regulation of larval salivary gland boundary specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism." [GOC:go_curators, GOC:tb] +synonym: "regulation of larval salivary gland determination" EXACT [GOC:tb] +is_a: GO:0045704 ! regulation of salivary gland boundary specification +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007433 ! larval salivary gland boundary specification +relationship: regulates GO:0007433 ! larval salivary gland boundary specification + +[Term] +id: GO:0045709 +name: negative regulation of adult salivary gland boundary specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism." [GOC:go_curators, GOC:tb] +synonym: "down regulation of adult salivary gland determination" EXACT [] +synonym: "down-regulation of adult salivary gland determination" EXACT [] +synonym: "downregulation of adult salivary gland determination" EXACT [] +synonym: "inhibition of adult salivary gland determination" NARROW [] +synonym: "negative regulation of adult salivary gland determination" EXACT [GOC:tb] +is_a: GO:0045705 ! negative regulation of salivary gland boundary specification +is_a: GO:0045707 ! regulation of adult salivary gland boundary specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007434 ! adult salivary gland boundary specification +relationship: negatively_regulates GO:0007434 ! adult salivary gland boundary specification + +[Term] +id: GO:0045710 +name: negative regulation of larval salivary gland boundary specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism." [GOC:go_curators, GOC:tb] +synonym: "down regulation of larval salivary gland determination" EXACT [] +synonym: "down-regulation of larval salivary gland determination" EXACT [] +synonym: "downregulation of larval salivary gland determination" EXACT [] +synonym: "inhibition of larval salivary gland determination" NARROW [] +synonym: "negative regulation of larval salivary gland determination" EXACT [GOC:tb] +is_a: GO:0045705 ! negative regulation of salivary gland boundary specification +is_a: GO:0045708 ! regulation of larval salivary gland boundary specification +is_a: GO:0048581 ! negative regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007433 ! larval salivary gland boundary specification +relationship: negatively_regulates GO:0007433 ! larval salivary gland boundary specification + +[Term] +id: GO:0045711 +name: positive regulation of adult salivary gland boundary specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism." [GOC:go_curators, GOC:tb] +synonym: "activation of adult salivary gland determination" NARROW [] +synonym: "positive regulation of adult salivary gland determination" EXACT [GOC:tb] +synonym: "stimulation of adult salivary gland determination" NARROW [] +synonym: "up regulation of adult salivary gland determination" EXACT [] +synonym: "up-regulation of adult salivary gland determination" EXACT [] +synonym: "upregulation of adult salivary gland determination" EXACT [] +is_a: GO:0045706 ! positive regulation of salivary gland boundary specification +is_a: GO:0045707 ! regulation of adult salivary gland boundary specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007434 ! adult salivary gland boundary specification +relationship: positively_regulates GO:0007434 ! adult salivary gland boundary specification + +[Term] +id: GO:0045712 +name: positive regulation of larval salivary gland boundary specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism." [GOC:go_curators, GOC:tb] +synonym: "activation of larval salivary gland determination" NARROW [] +synonym: "positive regulation of larval salivary gland determination" EXACT [GOC:tb] +synonym: "stimulation of larval salivary gland determination" NARROW [] +synonym: "up regulation of larval salivary gland determination" EXACT [] +synonym: "up-regulation of larval salivary gland determination" EXACT [] +synonym: "upregulation of larval salivary gland determination" EXACT [] +is_a: GO:0045706 ! positive regulation of salivary gland boundary specification +is_a: GO:0045708 ! regulation of larval salivary gland boundary specification +is_a: GO:0048582 ! positive regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007433 ! larval salivary gland boundary specification +relationship: positively_regulates GO:0007433 ! larval salivary gland boundary specification + +[Term] +id: GO:0045713 +name: low-density lipoprotein particle receptor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells." [GOC:go_curators] +synonym: "LDLr biosynthesis" EXACT [] +synonym: "LDLr biosynthetic process" EXACT [] +synonym: "low-density lipoprotein receptor anabolism" EXACT [] +synonym: "low-density lipoprotein receptor biosynthesis" EXACT [] +synonym: "low-density lipoprotein receptor biosynthetic process" EXACT [GOC:dph] +synonym: "low-density lipoprotein receptor formation" EXACT [] +synonym: "low-density lipoprotein receptor synthesis" EXACT [] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0032799 ! low-density lipoprotein receptor particle metabolic process +is_a: GO:0032800 ! receptor biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0045714 +name: regulation of low-density lipoprotein particle receptor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors." [GOC:go_curators] +synonym: "regulation of LDLr biosynthesis" EXACT [] +synonym: "regulation of LDLr biosynthetic process" EXACT [] +synonym: "regulation of low-density lipoprotein receptor anabolism" EXACT [] +synonym: "regulation of low-density lipoprotein receptor biosynthesis" EXACT [] +synonym: "regulation of low-density lipoprotein receptor biosynthetic process" EXACT [GOC:dph] +synonym: "regulation of low-density lipoprotein receptor formation" EXACT [] +synonym: "regulation of low-density lipoprotein receptor synthesis" EXACT [] +is_a: GO:0010869 ! regulation of receptor biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process +relationship: regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process + +[Term] +id: GO:0045715 +name: negative regulation of low-density lipoprotein particle receptor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors." [GOC:go_curators] +synonym: "down regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +synonym: "down-regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +synonym: "downregulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +synonym: "inhibition of low-density lipoprotein receptor biosynthetic process" NARROW [] +synonym: "negative regulation of low-density lipoprotein receptor anabolism" EXACT [] +synonym: "negative regulation of low-density lipoprotein receptor biosynthesis" EXACT [] +synonym: "negative regulation of low-density lipoprotein receptor biosynthetic process" EXACT [GOC:dph] +synonym: "negative regulation of low-density lipoprotein receptor formation" EXACT [] +synonym: "negative regulation of low-density lipoprotein receptor synthesis" EXACT [] +is_a: GO:0010871 ! negative regulation of receptor biosynthetic process +is_a: GO:0045714 ! regulation of low-density lipoprotein particle receptor biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process +relationship: negatively_regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process + +[Term] +id: GO:0045716 +name: positive regulation of low-density lipoprotein particle receptor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors." [GOC:go_curators] +synonym: "activation of low-density lipoprotein receptor biosynthetic process" NARROW [] +synonym: "positive regulation of low-density lipoprotein receptor anabolism" EXACT [] +synonym: "positive regulation of low-density lipoprotein receptor biosynthesis" EXACT [] +synonym: "positive regulation of low-density lipoprotein receptor biosynthetic process" EXACT [GOC:dph] +synonym: "positive regulation of low-density lipoprotein receptor formation" EXACT [] +synonym: "positive regulation of low-density lipoprotein receptor synthesis" EXACT [] +synonym: "stimulation of low-density lipoprotein receptor biosynthetic process" NARROW [] +synonym: "up regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +synonym: "up-regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +synonym: "upregulation of low-density lipoprotein receptor biosynthetic process" EXACT [] +is_a: GO:0010870 ! positive regulation of receptor biosynthetic process +is_a: GO:0045714 ! regulation of low-density lipoprotein particle receptor biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process +relationship: positively_regulates GO:0045713 ! low-density lipoprotein particle receptor biosynthetic process + +[Term] +id: GO:0045717 +name: negative regulation of fatty acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] +synonym: "down regulation of fatty acid biosynthetic process" EXACT [] +synonym: "down-regulation of fatty acid biosynthetic process" EXACT [] +synonym: "downregulation of fatty acid biosynthetic process" EXACT [] +synonym: "inhibition of fatty acid biosynthetic process" NARROW [] +synonym: "negative regulation of fatty acid anabolism" EXACT [] +synonym: "negative regulation of fatty acid biosynthesis" EXACT [] +synonym: "negative regulation of fatty acid formation" EXACT [] +synonym: "negative regulation of fatty acid synthesis" EXACT [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +is_a: GO:0045922 ! negative regulation of fatty acid metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006633 ! fatty acid biosynthetic process +relationship: negatively_regulates GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0045718 +name: obsolete negative regulation of flagellum assembly +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a flagellum." [GOC:go_curators] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "down regulation of flagellum assembly" EXACT [] +synonym: "down-regulation of flagellum assembly" EXACT [] +synonym: "downregulation of flagellum assembly" EXACT [] +synonym: "inhibition of flagellum assembly" NARROW [] +synonym: "negative regulation of flagella assembly" EXACT [] +synonym: "negative regulation of flagellum assembly" EXACT [] +synonym: "negative regulation of flagellum biogenesis" RELATED [GOC:mah] +is_obsolete: true +consider: GO:1902018 + +[Term] +id: GO:0045719 +name: negative regulation of glycogen biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] +synonym: "down regulation of glycogen biosynthetic process" EXACT [] +synonym: "down-regulation of glycogen biosynthetic process" EXACT [] +synonym: "downregulation of glycogen biosynthetic process" EXACT [] +synonym: "inhibition of glycogen biosynthetic process" NARROW [] +synonym: "negative regulation of glycogen anabolism" EXACT [] +synonym: "negative regulation of glycogen biosynthesis" EXACT [] +synonym: "negative regulation of glycogen formation" EXACT [] +synonym: "negative regulation of glycogen synthesis" EXACT [] +is_a: GO:0005979 ! regulation of glycogen biosynthetic process +is_a: GO:0070874 ! negative regulation of glycogen metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005978 ! glycogen biosynthetic process +relationship: negatively_regulates GO:0005978 ! glycogen biosynthetic process + +[Term] +id: GO:0045720 +name: negative regulation of integrin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] +synonym: "down regulation of integrin biosynthetic process" EXACT [] +synonym: "down-regulation of integrin biosynthetic process" EXACT [] +synonym: "downregulation of integrin biosynthetic process" EXACT [] +synonym: "inhibition of integrin biosynthetic process" NARROW [] +synonym: "negative regulation of integrin anabolism" EXACT [] +synonym: "negative regulation of integrin biosynthesis" EXACT [] +synonym: "negative regulation of integrin formation" EXACT [] +synonym: "negative regulation of integrin synthesis" EXACT [] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0045113 ! regulation of integrin biosynthetic process +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045112 ! integrin biosynthetic process +relationship: negatively_regulates GO:0045112 ! integrin biosynthetic process + +[Term] +id: GO:0045721 +name: negative regulation of gluconeogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] +synonym: "down regulation of gluconeogenesis" EXACT [] +synonym: "down-regulation of gluconeogenesis" EXACT [] +synonym: "downregulation of gluconeogenesis" EXACT [] +synonym: "inhibition of gluconeogenesis" NARROW [] +is_a: GO:0006111 ! regulation of gluconeogenesis +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006094 ! gluconeogenesis +relationship: negatively_regulates GO:0006094 ! gluconeogenesis + +[Term] +id: GO:0045722 +name: positive regulation of gluconeogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] +synonym: "activation of gluconeogenesis" NARROW [] +synonym: "stimulation of gluconeogenesis" NARROW [] +synonym: "up regulation of gluconeogenesis" EXACT [] +synonym: "up-regulation of gluconeogenesis" EXACT [] +synonym: "upregulation of gluconeogenesis" EXACT [] +is_a: GO:0006111 ! regulation of gluconeogenesis +is_a: GO:0010907 ! positive regulation of glucose metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006094 ! gluconeogenesis +relationship: positively_regulates GO:0006094 ! gluconeogenesis + +[Term] +id: GO:0045723 +name: positive regulation of fatty acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] +synonym: "activation of fatty acid biosynthetic process" NARROW [] +synonym: "positive regulation of fatty acid anabolism" EXACT [] +synonym: "positive regulation of fatty acid biosynthesis" EXACT [] +synonym: "positive regulation of fatty acid formation" EXACT [] +synonym: "positive regulation of fatty acid synthesis" EXACT [] +synonym: "stimulation of fatty acid biosynthetic process" NARROW [] +synonym: "up regulation of fatty acid biosynthetic process" EXACT [] +synonym: "up-regulation of fatty acid biosynthetic process" EXACT [] +synonym: "upregulation of fatty acid biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +is_a: GO:0045923 ! positive regulation of fatty acid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006633 ! fatty acid biosynthetic process +relationship: positively_regulates GO:0006633 ! fatty acid biosynthetic process + +[Term] +id: GO:0045724 +name: positive regulation of cilium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators] +synonym: "activation of cilium assembly" NARROW [] +synonym: "positive regulation of flagellum assembly" BROAD [] +synonym: "positive regulation of flagellum biogenesis" RELATED [GOC:mah] +synonym: "stimulation of cilium assembly" NARROW [] +synonym: "up regulation of cilium assembly" EXACT [] +synonym: "up-regulation of cilium assembly" EXACT [] +synonym: "upregulation of cilium assembly" EXACT [] +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902017 ! regulation of cilium assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060271 ! cilium assembly +relationship: positively_regulates GO:0060271 ! cilium assembly + +[Term] +id: GO:0045725 +name: positive regulation of glycogen biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] +synonym: "activation of glycogen biosynthetic process" NARROW [] +synonym: "positive regulation of glycogen anabolism" EXACT [] +synonym: "positive regulation of glycogen biosynthesis" EXACT [] +synonym: "positive regulation of glycogen formation" EXACT [] +synonym: "positive regulation of glycogen synthesis" EXACT [] +synonym: "stimulation of glycogen biosynthetic process" NARROW [] +synonym: "up regulation of glycogen biosynthetic process" EXACT [] +synonym: "up-regulation of glycogen biosynthetic process" EXACT [] +synonym: "upregulation of glycogen biosynthetic process" EXACT [] +is_a: GO:0005979 ! regulation of glycogen biosynthetic process +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0070875 ! positive regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005978 ! glycogen biosynthetic process +relationship: positively_regulates GO:0005978 ! glycogen biosynthetic process + +[Term] +id: GO:0045726 +name: positive regulation of integrin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] +synonym: "activation of integrin biosynthetic process" NARROW [] +synonym: "positive regulation of integrin anabolism" EXACT [] +synonym: "positive regulation of integrin biosynthesis" EXACT [] +synonym: "positive regulation of integrin formation" EXACT [] +synonym: "positive regulation of integrin synthesis" EXACT [] +synonym: "stimulation of integrin biosynthetic process" NARROW [] +synonym: "up regulation of integrin biosynthetic process" EXACT [] +synonym: "up-regulation of integrin biosynthetic process" EXACT [] +synonym: "upregulation of integrin biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0045113 ! regulation of integrin biosynthetic process +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045112 ! integrin biosynthetic process +relationship: positively_regulates GO:0045112 ! integrin biosynthetic process + +[Term] +id: GO:0045727 +name: positive regulation of translation +namespace: biological_process +alt_id: GO:0045946 +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of protein biosynthetic process" NARROW [] +synonym: "positive regulation of protein anabolism" EXACT [] +synonym: "positive regulation of protein biosynthesis" EXACT [] +synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] +synonym: "positive regulation of protein formation" EXACT [] +synonym: "positive regulation of protein synthesis" EXACT [] +synonym: "stimulation of protein biosynthetic process" NARROW [] +synonym: "up regulation of protein biosynthetic process" EXACT [] +synonym: "up-regulation of protein biosynthetic process" EXACT [] +synonym: "upregulation of protein biosynthetic process" EXACT [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0032270 ! positive regulation of cellular protein metabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006412 ! translation +relationship: positively_regulates GO:0006412 ! translation + +[Term] +id: GO:0045728 +name: respiratory burst after phagocytosis +namespace: biological_process +def: "A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity." [GOC:curators, ISBN:0198506732] +synonym: "metabolic burst after phagocytosis" EXACT [] +synonym: "oxidative burst after phagocytosis" EXACT [] +is_a: GO:0002679 ! respiratory burst involved in defense response + +[Term] +id: GO:0045729 +name: respiratory burst at fertilization +namespace: biological_process +def: "The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes." [ISBN:0198506732, PMID:2537493, PMID:9013127] +synonym: "metabolic burst at fertilization" EXACT [] +synonym: "oxidative burst at fertilization" EXACT [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0045730 ! respiratory burst +intersection_of: GO:0045730 ! respiratory burst +intersection_of: part_of GO:0009566 ! fertilization +relationship: part_of GO:0007338 ! single fertilization + +[Term] +id: GO:0045730 +name: respiratory burst +namespace: biological_process +def: "A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [ISBN:0198506732] +synonym: "metabolic burst" EXACT [] +synonym: "oxidative burst" EXACT [] +xref: Wikipedia:Respiratory_burst +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0045732 +name: positive regulation of protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators] +synonym: "activation of protein catabolic process" NARROW [] +synonym: "positive regulation of protein breakdown" EXACT [] +synonym: "positive regulation of protein catabolism" EXACT [] +synonym: "positive regulation of protein degradation" EXACT [] +synonym: "stimulation of protein catabolic process" NARROW [] +synonym: "up regulation of protein catabolic process" EXACT [] +synonym: "up-regulation of protein catabolic process" EXACT [] +synonym: "upregulation of protein catabolic process" EXACT [] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0042176 ! regulation of protein catabolic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030163 ! protein catabolic process +relationship: positively_regulates GO:0030163 ! protein catabolic process + +[Term] +id: GO:0045733 +name: acetate catabolic process +namespace: biological_process +alt_id: GO:0019663 +def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] +synonym: "acetate breakdown" EXACT [] +synonym: "acetate catabolism" EXACT [] +synonym: "acetate degradation" EXACT [] +synonym: "homoacetate catabolic process" RELATED [] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0045734 +name: regulation of acetate catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] +synonym: "regulation of acetate breakdown" EXACT [] +synonym: "regulation of acetate catabolism" EXACT [] +synonym: "regulation of acetate degradation" EXACT [] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045733 ! acetate catabolic process +relationship: regulates GO:0045733 ! acetate catabolic process + +[Term] +id: GO:0045735 +name: nutrient reservoir activity +namespace: molecular_function +def: "Functions in the storage of nutritious substrates." [GOC:ai] +comment: Note that this term can be used in place of the obsolete terms 'storage protein ; GO:0005187' and 'storage protein of fat body (sensu Insecta) ; GO:0008041'. +subset: goslim_pir +synonym: "storage protein" RELATED [] +synonym: "storage protein of fat body" RELATED [] +synonym: "yolk protein" RELATED [] +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0045736 +name: negative regulation of cyclin-dependent protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity." [GOC:go_curators, GOC:pr] +is_a: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity +is_a: GO:0045786 ! negative regulation of cell cycle +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +is_a: GO:1904030 ! negative regulation of cyclin-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity +relationship: negatively_regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0045737 +name: positive regulation of cyclin-dependent protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CDK activity." [GOC:go_curators, GOC:pr] +synonym: "activation of cyclin-dependent protein kinase activity" BROAD [] +synonym: "positive regulation of CDK activity" BROAD [] +synonym: "positive regulation of cyclin-dependent protein kinase activity" BROAD [GOC:pr] +synonym: "stimulation of cyclin-dependent protein kinase activity" BROAD [] +synonym: "up regulation of cyclin-dependent protein kinase activity" BROAD [] +synonym: "up-regulation of cyclin-dependent protein kinase activity" BROAD [] +synonym: "upregulation of cyclin-dependent protein kinase activity" BROAD [] +is_a: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity +is_a: GO:0045787 ! positive regulation of cell cycle +is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity +is_a: GO:1904031 ! positive regulation of cyclin-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity +relationship: positively_regulates GO:0004693 ! cyclin-dependent protein serine/threonine kinase activity + +[Term] +id: GO:0045738 +name: negative regulation of DNA repair +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair." [GOC:go_curators] +synonym: "down regulation of DNA repair" EXACT [] +synonym: "down-regulation of DNA repair" EXACT [] +synonym: "downregulation of DNA repair" EXACT [] +synonym: "inhibition of DNA repair" NARROW [] +is_a: GO:0006282 ! regulation of DNA repair +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:2001021 ! negative regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006281 ! DNA repair +relationship: negatively_regulates GO:0006281 ! DNA repair + +[Term] +id: GO:0045739 +name: positive regulation of DNA repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA repair." [GOC:go_curators] +synonym: "activation of DNA repair" NARROW [] +synonym: "stimulation of DNA repair" NARROW [] +synonym: "up regulation of DNA repair" EXACT [] +synonym: "up-regulation of DNA repair" EXACT [] +synonym: "upregulation of DNA repair" EXACT [] +is_a: GO:0006282 ! regulation of DNA repair +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:2001022 ! positive regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006281 ! DNA repair +relationship: positively_regulates GO:0006281 ! DNA repair + +[Term] +id: GO:0045740 +name: positive regulation of DNA replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA replication." [GOC:go_curators] +synonym: "activation of DNA replication" NARROW [] +synonym: "stimulation of DNA replication" NARROW [] +synonym: "up regulation of DNA replication" EXACT [] +synonym: "up-regulation of DNA replication" EXACT [] +synonym: "upregulation of DNA replication" EXACT [] +is_a: GO:0006275 ! regulation of DNA replication +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006260 ! DNA replication +relationship: positively_regulates GO:0006260 ! DNA replication + +[Term] +id: GO:0045741 +name: positive regulation of epidermal growth factor-activated receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity." [GOC:go_curators] +synonym: "activation of epidermal growth factor receptor activity" NARROW [] +synonym: "positive regulation of EGF receptor activity" EXACT [] +synonym: "positive regulation of EGFR activity" EXACT [] +synonym: "positive regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "stimulation of epidermal growth factor receptor activity" NARROW [] +synonym: "up regulation of epidermal growth factor receptor activity" EXACT [] +synonym: "up-regulation of epidermal growth factor receptor activity" EXACT [] +synonym: "upregulation of epidermal growth factor receptor activity" EXACT [] +is_a: GO:0007176 ! regulation of epidermal growth factor-activated receptor activity +is_a: GO:0045742 ! positive regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0061098 ! positive regulation of protein tyrosine kinase activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005006 ! epidermal growth factor-activated receptor activity +relationship: positively_regulates GO:0005006 ! epidermal growth factor-activated receptor activity + +[Term] +id: GO:0045742 +name: positive regulation of epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "activation of epidermal growth factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of EGF receptor signaling pathway" EXACT [] +synonym: "positive regulation of EGF receptor signalling pathway" EXACT [] +synonym: "positive regulation of EGFR signaling pathway" EXACT [] +synonym: "stimulation of epidermal growth factor receptor signaling pathway" NARROW [] +synonym: "up regulation of epidermal growth factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of epidermal growth factor receptor signaling pathway" EXACT [] +synonym: "upregulation of epidermal growth factor receptor signaling pathway" EXACT [] +is_a: GO:0042058 ! regulation of epidermal growth factor receptor signaling pathway +is_a: GO:1901186 ! positive regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: positively_regulates GO:0007173 ! epidermal growth factor receptor signaling pathway + +[Term] +id: GO:0045743 +name: positive regulation of fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] +synonym: "activation of fibroblast growth factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of FGF receptor signaling pathway" EXACT [] +synonym: "positive regulation of FGF receptor signalling pathway" EXACT [] +synonym: "positive regulation of FGFR signaling pathway" EXACT [] +synonym: "stimulation of fibroblast growth factor receptor signaling pathway" NARROW [] +synonym: "up regulation of fibroblast growth factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of fibroblast growth factor receptor signaling pathway" EXACT [] +synonym: "upregulation of fibroblast growth factor receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway +relationship: positively_regulates GO:0008543 ! fibroblast growth factor receptor signaling pathway + +[Term] +id: GO:0045744 +name: negative regulation of G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway." [GOC:go_curators] +synonym: "down regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "down-regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "downregulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "inhibition of G-protein coupled receptor protein signaling pathway" NARROW [] +synonym: "negative regulation of G protein coupled receptor protein signaling pathway" EXACT [] +synonym: "negative regulation of G protein coupled receptor protein signalling pathway" EXACT [] +synonym: "negative regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "negative regulation of G-protein coupled receptor protein signalling pathway" EXACT [] +synonym: "negative regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] +synonym: "negative regulation of GPCR protein signaling pathway" EXACT [] +synonym: "negative regulation of GPCR protein signalling pathway" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: negatively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0045745 +name: positive regulation of G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity." [GOC:go_curators] +synonym: "activation of G-protein coupled receptor protein signaling pathway" NARROW [] +synonym: "positive regulation of G protein coupled receptor protein signaling pathway" EXACT [] +synonym: "positive regulation of G protein coupled receptor protein signalling pathway" EXACT [] +synonym: "positive regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "positive regulation of G-protein coupled receptor protein signalling pathway" EXACT [] +synonym: "positive regulation of G-protein-coupled receptor protein signaling pathway" EXACT [] +synonym: "positive regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] +synonym: "positive regulation of GPCR protein signaling pathway" EXACT [] +synonym: "positive regulation of GPCR protein signalling pathway" EXACT [] +synonym: "stimulation of G-protein coupled receptor protein signaling pathway" NARROW [] +synonym: "up regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "up-regulation of G-protein coupled receptor protein signaling pathway" EXACT [] +synonym: "upregulation of G-protein coupled receptor protein signaling pathway" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: positively_regulates GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0045746 +name: negative regulation of Notch signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] +synonym: "down regulation of Notch signaling pathway" EXACT [] +synonym: "down-regulation of Notch signaling pathway" EXACT [] +synonym: "downregulation of Notch signaling pathway" EXACT [] +synonym: "inhibition of Notch signaling pathway" NARROW [] +synonym: "negative regulation of N signaling pathway" EXACT [] +synonym: "negative regulation of N signalling pathway" EXACT [] +synonym: "negative regulation of Notch signalling pathway" EXACT [] +is_a: GO:0008593 ! regulation of Notch signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007219 ! Notch signaling pathway +relationship: negatively_regulates GO:0007219 ! Notch signaling pathway + +[Term] +id: GO:0045747 +name: positive regulation of Notch signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] +synonym: "activation of Notch signaling pathway" NARROW [] +synonym: "positive regulation of N signaling pathway" EXACT [] +synonym: "positive regulation of N signalling pathway" EXACT [] +synonym: "positive regulation of Notch signalling pathway" EXACT [] +synonym: "stimulation of Notch signaling pathway" NARROW [] +synonym: "up regulation of Notch signaling pathway" EXACT [] +synonym: "up-regulation of Notch signaling pathway" EXACT [] +synonym: "upregulation of Notch signaling pathway" EXACT [] +is_a: GO:0008593 ! regulation of Notch signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007219 ! Notch signaling pathway +relationship: positively_regulates GO:0007219 ! Notch signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0045748 +name: positive regulation of R8 cell spacing in compound eye +namespace: biological_process +def: "Any process that activates or enforces the correct R8 cell spacing in a compound eye." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of R8 spacing" NARROW [] +synonym: "positive regulation of R8 spacing" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of R8 spacing" NARROW [] +synonym: "up regulation of R8 spacing" EXACT [] +synonym: "up-regulation of R8 spacing" EXACT [] +synonym: "upregulation of R8 spacing" EXACT [] +is_a: GO:0045468 ! regulation of R8 cell spacing in compound eye + +[Term] +id: GO:0045749 +name: obsolete negative regulation of S phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "down regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "down-regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "downregulation of S phase of mitotic cell cycle" EXACT [] +synonym: "inhibition of S phase of mitotic cell cycle" NARROW [] +synonym: "negative regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "negative regulation of S-phase of mitotic cell cycle" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045750 +name: obsolete positive regulation of S phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "activation of S phase of mitotic cell cycle" NARROW [] +synonym: "positive regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "positive regulation of S-phase of mitotic cell cycle" EXACT [] +synonym: "stimulation of S phase of mitotic cell cycle" NARROW [] +synonym: "up regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "up-regulation of S phase of mitotic cell cycle" EXACT [] +synonym: "upregulation of S phase of mitotic cell cycle" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045751 +name: negative regulation of Toll signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] +synonym: "down regulation of Toll signaling pathway" EXACT [] +synonym: "down-regulation of Toll signaling pathway" EXACT [] +synonym: "downregulation of Toll signaling pathway" EXACT [] +synonym: "inhibition of Toll signaling pathway" NARROW [] +synonym: "negative regulation of Tl signaling pathway" EXACT [] +synonym: "negative regulation of Tl signalling pathway" EXACT [] +is_a: GO:0008592 ! regulation of Toll signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008063 ! Toll signaling pathway +relationship: negatively_regulates GO:0008063 ! Toll signaling pathway + +[Term] +id: GO:0045752 +name: positive regulation of Toll signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] +synonym: "activation of Toll signaling pathway" NARROW [] +synonym: "positive regulation of Tl signaling pathway" EXACT [] +synonym: "positive regulation of Tl signalling pathway" EXACT [] +synonym: "stimulation of Toll signaling pathway" NARROW [] +synonym: "up regulation of Toll signaling pathway" EXACT [] +synonym: "up-regulation of Toll signaling pathway" EXACT [] +synonym: "upregulation of Toll signaling pathway" EXACT [] +is_a: GO:0008592 ! regulation of Toll signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008063 ! Toll signaling pathway +relationship: positively_regulates GO:0008063 ! Toll signaling pathway + +[Term] +id: GO:0045753 +name: negative regulation of acetate catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] +synonym: "down regulation of acetate catabolic process" EXACT [] +synonym: "down-regulation of acetate catabolic process" EXACT [] +synonym: "downregulation of acetate catabolic process" EXACT [] +synonym: "inhibition of acetate catabolic process" NARROW [] +synonym: "negative regulation of acetate breakdown" EXACT [] +synonym: "negative regulation of acetate catabolism" EXACT [] +synonym: "negative regulation of acetate degradation" EXACT [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045734 ! regulation of acetate catabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045733 ! acetate catabolic process +relationship: negatively_regulates GO:0045733 ! acetate catabolic process + +[Term] +id: GO:0045754 +name: positive regulation of acetate catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] +synonym: "activation of acetate catabolic process" NARROW [] +synonym: "positive regulation of acetate breakdown" EXACT [] +synonym: "positive regulation of acetate catabolism" EXACT [] +synonym: "positive regulation of acetate degradation" EXACT [] +synonym: "stimulation of acetate catabolic process" NARROW [] +synonym: "up regulation of acetate catabolic process" EXACT [] +synonym: "up-regulation of acetate catabolic process" EXACT [] +synonym: "upregulation of acetate catabolic process" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045734 ! regulation of acetate catabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045733 ! acetate catabolic process +relationship: positively_regulates GO:0045733 ! acetate catabolic process + +[Term] +id: GO:0045755 +name: negative regulation of initiation of acetate catabolic process by acetate +namespace: biological_process +def: "Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] +synonym: "down regulation of initiation of acetate catabolic process by acetate" EXACT [] +synonym: "down-regulation of initiation of acetate catabolic process by acetate" EXACT [] +synonym: "downregulation of initiation of acetate catabolic process by acetate" EXACT [] +synonym: "inhibition of initiation of acetate catabolic process by acetate" NARROW [] +synonym: "negative regulation of initiation of acetate breakdown by acetate" EXACT [] +synonym: "negative regulation of initiation of acetate degradation by acetate" EXACT [] +is_a: GO:0045147 ! regulation of initiation of acetate catabolic process by acetate +is_a: GO:1901458 ! negative regulation of response to acetate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045146 ! initiation of acetate catabolic process by acetate +relationship: negatively_regulates GO:0045146 ! initiation of acetate catabolic process by acetate + +[Term] +id: GO:0045756 +name: positive regulation of initiation of acetate catabolic process by acetate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] +synonym: "activation of initiation of acetate catabolic process by acetate" NARROW [] +synonym: "positive regulation of initiation of acetate breakdown by acetate" EXACT [] +synonym: "positive regulation of initiation of acetate degradation by acetate" EXACT [] +synonym: "stimulation of initiation of acetate catabolic process by acetate" NARROW [] +synonym: "up regulation of initiation of acetate catabolic process by acetate" EXACT [] +synonym: "up-regulation of initiation of acetate catabolic process by acetate" EXACT [] +synonym: "upregulation of initiation of acetate catabolic process by acetate" EXACT [] +is_a: GO:0045147 ! regulation of initiation of acetate catabolic process by acetate +is_a: GO:0045754 ! positive regulation of acetate catabolic process +is_a: GO:1901459 ! positive regulation of response to acetate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045146 ! initiation of acetate catabolic process by acetate +relationship: positively_regulates GO:0045146 ! initiation of acetate catabolic process by acetate + +[Term] +id: GO:0045757 +name: obsolete negative regulation of actin polymerization and/or depolymerization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization and/or depolymerization." [GOC:go_curators] +comment: This term was made obsolete because it has been split. +synonym: "negative regulation of actin polymerization and/or depolymerization" EXACT [] +is_obsolete: true +consider: GO:0030835 +consider: GO:0030837 + +[Term] +id: GO:0045758 +name: obsolete positive regulation of actin polymerization and/or depolymerization +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization and/or depolymerization." [GOC:go_curators] +comment: This term was made obsolete because it has been split. +synonym: "positive regulation of actin polymerization and/or depolymerization" EXACT [] +is_obsolete: true +consider: GO:0030836 +consider: GO:0030838 + +[Term] +id: GO:0045759 +name: negative regulation of action potential +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] +synonym: "down regulation of action potential" EXACT [] +synonym: "down-regulation of action potential" EXACT [] +synonym: "downregulation of action potential" EXACT [] +synonym: "inhibition of action potential" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001508 ! action potential +relationship: negatively_regulates GO:0001508 ! action potential + +[Term] +id: GO:0045760 +name: positive regulation of action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] +synonym: "activation of action potential" NARROW [] +synonym: "stimulation of action potential" NARROW [] +synonym: "up regulation of action potential" EXACT [] +synonym: "up-regulation of action potential" EXACT [] +synonym: "upregulation of action potential" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001508 ! action potential +relationship: positively_regulates GO:0001508 ! action potential + +[Term] +id: GO:0045761 +name: regulation of adenylate cyclase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] +synonym: "adenylate cyclase regulator" RELATED [] +synonym: "regulation of adenylyl cyclase activity" EXACT [] +is_a: GO:0031279 ! regulation of cyclase activity +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004016 ! adenylate cyclase activity +relationship: regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0045762 +name: positive regulation of adenylate cyclase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] +synonym: "adenylate cyclase activator" RELATED [] +synonym: "positive regulation of adenylyl cyclase activity" EXACT [] +synonym: "stimulation of adenylate cyclase activity" NARROW [] +synonym: "up regulation of adenylate cyclase activity" EXACT [] +synonym: "up-regulation of adenylate cyclase activity" EXACT [] +synonym: "upregulation of adenylate cyclase activity" EXACT [] +is_a: GO:0031281 ! positive regulation of cyclase activity +is_a: GO:0045761 ! regulation of adenylate cyclase activity +is_a: GO:0051349 ! positive regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004016 ! adenylate cyclase activity +relationship: positively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0045763 +name: negative regulation of cellular amino acid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] +synonym: "down regulation of amino acid metabolic process" EXACT [] +synonym: "down-regulation of amino acid metabolic process" EXACT [] +synonym: "downregulation of amino acid metabolic process" EXACT [] +synonym: "inhibition of amino acid metabolic process" NARROW [] +synonym: "negative regulation of amino acid metabolism" EXACT [] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006520 ! cellular amino acid metabolic process +relationship: negatively_regulates GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0045764 +name: positive regulation of cellular amino acid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] +synonym: "activation of amino acid metabolic process" NARROW [] +synonym: "positive regulation of amino acid metabolism" EXACT [] +synonym: "stimulation of amino acid metabolic process" NARROW [] +synonym: "up regulation of amino acid metabolic process" EXACT [] +synonym: "up-regulation of amino acid metabolic process" EXACT [] +synonym: "upregulation of amino acid metabolic process" EXACT [] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006520 ! cellular amino acid metabolic process +relationship: positively_regulates GO:0006520 ! cellular amino acid metabolic process + +[Term] +id: GO:0045765 +name: regulation of angiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001525 ! angiogenesis +relationship: regulates GO:0001525 ! angiogenesis + +[Term] +id: GO:0045766 +name: positive regulation of angiogenesis +namespace: biological_process +def: "Any process that activates or increases angiogenesis." [GOC:go_curators] +synonym: "activation of angiogenesis" NARROW [] +synonym: "stimulation of angiogenesis" NARROW [] +synonym: "up regulation of angiogenesis" EXACT [] +synonym: "up-regulation of angiogenesis" EXACT [] +synonym: "upregulation of angiogenesis" EXACT [] +is_a: GO:0045765 ! regulation of angiogenesis +is_a: GO:1904018 ! positive regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001525 ! angiogenesis +relationship: positively_regulates GO:0001525 ! angiogenesis + +[Term] +id: GO:0045767 +name: obsolete regulation of anti-apoptosis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis." [GOC:go_curators, GOC:mtg_apoptosis] +comment: This term was made obsolete because it was ill-defined. +synonym: "regulation of anti-apoptosis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045768 +name: obsolete positive regulation of anti-apoptosis +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of anti-apoptosis." [GOC:go_curators, GOC:mtg_apoptosis] +comment: This term was made obsolete because it was ill-defined. +synonym: "activation of anti-apoptosis" NARROW [] +synonym: "positive regulation of anti-apoptosis" EXACT [] +synonym: "stimulation of anti-apoptosis" NARROW [] +synonym: "up regulation of anti-apoptosis" EXACT [] +synonym: "up-regulation of anti-apoptosis" EXACT [] +synonym: "upregulation of anti-apoptosis" EXACT [] +is_obsolete: true + +[Term] +id: GO:0045769 +name: negative regulation of asymmetric cell division +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] +synonym: "down regulation of asymmetric cell division" EXACT [] +synonym: "down-regulation of asymmetric cell division" EXACT [] +synonym: "downregulation of asymmetric cell division" EXACT [] +synonym: "inhibition of asymmetric cell division" NARROW [] +is_a: GO:0009786 ! regulation of asymmetric cell division +is_a: GO:0051782 ! negative regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008356 ! asymmetric cell division +relationship: negatively_regulates GO:0008356 ! asymmetric cell division + +[Term] +id: GO:0045770 +name: positive regulation of asymmetric cell division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] +synonym: "activation of asymmetric cell division" NARROW [] +synonym: "stimulation of asymmetric cell division" NARROW [] +synonym: "up regulation of asymmetric cell division" EXACT [] +synonym: "up-regulation of asymmetric cell division" EXACT [] +synonym: "upregulation of asymmetric cell division" EXACT [] +is_a: GO:0009786 ! regulation of asymmetric cell division +is_a: GO:0051781 ! positive regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008356 ! asymmetric cell division +relationship: positively_regulates GO:0008356 ! asymmetric cell division + +[Term] +id: GO:0045771 +name: negative regulation of autophagosome size +namespace: biological_process +def: "Any process that reduces autophagosome size." [GOC:autophagy, GOC:go_curators] +synonym: "down regulation of autophagic vacuole size" EXACT [] +synonym: "down-regulation of autophagic vacuole size" EXACT [] +synonym: "downregulation of autophagic vacuole size" EXACT [] +synonym: "inhibition of autophagic vacuole size" NARROW [] +synonym: "negative regulation of autophagic vacuole size" EXACT [GOC:autophagy] +is_a: GO:0016243 ! regulation of autophagosome size + +[Term] +id: GO:0045772 +name: positive regulation of autophagosome size +namespace: biological_process +def: "Any process that increases autophagosome size." [GOC:autophagy, GOC:go_curators] +synonym: "activation of autophagic vacuole size" NARROW [] +synonym: "positive regulation of autophagic vacuole size" EXACT [GOC:autophagy] +synonym: "stimulation of autophagic vacuole size" NARROW [] +synonym: "up regulation of autophagic vacuole size" EXACT [] +synonym: "up-regulation of autophagic vacuole size" EXACT [] +synonym: "upregulation of autophagic vacuole size" EXACT [] +is_a: GO:0016243 ! regulation of autophagosome size + +[Term] +id: GO:0045773 +name: positive regulation of axon extension +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axon extension." [GOC:go_curators] +synonym: "activation of axon extension" NARROW [] +synonym: "stimulation of axon extension" NARROW [] +synonym: "up regulation of axon extension" EXACT [] +synonym: "up-regulation of axon extension" EXACT [] +synonym: "upregulation of axon extension" EXACT [] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0030516 ! regulation of axon extension +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0050772 ! positive regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048675 ! axon extension +relationship: positively_regulates GO:0048675 ! axon extension + +[Term] +id: GO:0045774 +name: negative regulation of beta 2 integrin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] +synonym: "down regulation of beta 2 integrin biosynthetic process" EXACT [] +synonym: "down-regulation of beta 2 integrin biosynthetic process" EXACT [] +synonym: "downregulation of beta 2 integrin biosynthetic process" EXACT [] +synonym: "inhibition of beta 2 integrin biosynthetic process" NARROW [] +synonym: "negative regulation of beta 2 integrin anabolism" EXACT [] +synonym: "negative regulation of beta 2 integrin biosynthesis" EXACT [] +synonym: "negative regulation of beta 2 integrin formation" EXACT [] +synonym: "negative regulation of beta 2 integrin synthesis" EXACT [] +is_a: GO:0045115 ! regulation of beta 2 integrin biosynthetic process +is_a: GO:0045720 ! negative regulation of integrin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045114 ! beta 2 integrin biosynthetic process +relationship: negatively_regulates GO:0045114 ! beta 2 integrin biosynthetic process + +[Term] +id: GO:0045775 +name: positive regulation of beta 2 integrin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] +synonym: "activation of beta 2 integrin biosynthetic process" NARROW [] +synonym: "positive regulation of beta 2 integrin anabolism" EXACT [] +synonym: "positive regulation of beta 2 integrin biosynthesis" EXACT [] +synonym: "positive regulation of beta 2 integrin formation" EXACT [] +synonym: "positive regulation of beta 2 integrin synthesis" EXACT [] +synonym: "stimulation of beta 2 integrin biosynthetic process" NARROW [] +synonym: "up regulation of beta 2 integrin biosynthetic process" EXACT [] +synonym: "up-regulation of beta 2 integrin biosynthetic process" EXACT [] +synonym: "upregulation of beta 2 integrin biosynthetic process" EXACT [] +is_a: GO:0045115 ! regulation of beta 2 integrin biosynthetic process +is_a: GO:0045726 ! positive regulation of integrin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045114 ! beta 2 integrin biosynthetic process +relationship: positively_regulates GO:0045114 ! beta 2 integrin biosynthetic process + +[Term] +id: GO:0045776 +name: negative regulation of blood pressure +namespace: biological_process +def: "Any process in which the force of blood traveling through the circulatory system is decreased." [GOC:go_curators, GOC:mtg_cardio] +synonym: "down regulation of blood pressure" EXACT [] +synonym: "down-regulation of blood pressure" EXACT [] +synonym: "downregulation of blood pressure" EXACT [] +synonym: "inhibition of blood pressure" NARROW [] +is_a: GO:0008217 ! regulation of blood pressure + +[Term] +id: GO:0045777 +name: positive regulation of blood pressure +namespace: biological_process +def: "Any process in which the force of blood traveling through the circulatory system is increased." [GOC:go_curators, GOC:mtg_cardio] +synonym: "activation of blood pressure" NARROW [] +synonym: "stimulation of blood pressure" NARROW [] +synonym: "up regulation of blood pressure" EXACT [] +synonym: "up-regulation of blood pressure" EXACT [] +synonym: "upregulation of blood pressure" EXACT [] +is_a: GO:0008217 ! regulation of blood pressure + +[Term] +id: GO:0045778 +name: positive regulation of ossification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] +synonym: "activation of ossification" NARROW [] +synonym: "positive regulation of bone biosynthesis" EXACT [] +synonym: "positive regulation of bone formation" EXACT [] +synonym: "stimulation of ossification" NARROW [] +synonym: "up regulation of ossification" EXACT [] +synonym: "up-regulation of ossification" EXACT [] +synonym: "upregulation of ossification" EXACT [] +is_a: GO:0030278 ! regulation of ossification +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001503 ! ossification +relationship: positively_regulates GO:0001503 ! ossification + +[Term] +id: GO:0045779 +name: negative regulation of bone resorption +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption." [GOC:go_curators] +synonym: "down regulation of bone resorption" EXACT [] +synonym: "down-regulation of bone resorption" EXACT [] +synonym: "downregulation of bone resorption" EXACT [] +synonym: "inhibition of bone resorption" NARROW [] +is_a: GO:0045124 ! regulation of bone resorption +is_a: GO:0046851 ! negative regulation of bone remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045453 ! bone resorption +relationship: negatively_regulates GO:0045453 ! bone resorption + +[Term] +id: GO:0045780 +name: positive regulation of bone resorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone resorption." [GOC:go_curators] +synonym: "activation of bone resorption" NARROW [] +synonym: "stimulation of bone resorption" NARROW [] +synonym: "up regulation of bone resorption" EXACT [] +synonym: "up-regulation of bone resorption" EXACT [] +synonym: "upregulation of bone resorption" EXACT [] +is_a: GO:0045124 ! regulation of bone resorption +is_a: GO:0046852 ! positive regulation of bone remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045453 ! bone resorption +relationship: positively_regulates GO:0045453 ! bone resorption + +[Term] +id: GO:0045781 +name: negative regulation of cell budding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding." [GOC:go_curators] +synonym: "down regulation of cell budding" EXACT [] +synonym: "down-regulation of cell budding" EXACT [] +synonym: "downregulation of cell budding" EXACT [] +synonym: "inhibition of cell budding" NARROW [] +synonym: "negative regulation of budding" BROAD [] +is_a: GO:0007116 ! regulation of cell budding +is_a: GO:0051782 ! negative regulation of cell division +is_a: GO:1903665 ! negative regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007114 ! cell budding +relationship: negatively_regulates GO:0007114 ! cell budding + +[Term] +id: GO:0045782 +name: positive regulation of cell budding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell budding." [GOC:go_curators] +synonym: "activation of cell budding" NARROW [] +synonym: "positive regulation of budding" BROAD [] +synonym: "stimulation of cell budding" NARROW [] +synonym: "up regulation of cell budding" EXACT [] +synonym: "up-regulation of cell budding" EXACT [] +synonym: "upregulation of cell budding" EXACT [] +is_a: GO:0007116 ! regulation of cell budding +is_a: GO:0051781 ! positive regulation of cell division +is_a: GO:1903666 ! positive regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007114 ! cell budding +relationship: positively_regulates GO:0007114 ! cell budding + +[Term] +id: GO:0045783 +name: obsolete negative regulation of calcium in ER +namespace: biological_process +def: "OBSOLETE. Any process that reduces the concentration of calcium in the ER." [GOC:go_curators] +comment: This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). +synonym: "negative regulation of calcium in ER" EXACT [] +is_obsolete: true +consider: GO:0005783 +consider: GO:0006874 + +[Term] +id: GO:0045784 +name: obsolete positive regulation of calcium in ER +namespace: biological_process +def: "OBSOLETE. Any process that increases the concentration of calcium in the ER." [GOC:go_curators] +comment: This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). +synonym: "positive regulation of calcium in ER" EXACT [] +is_obsolete: true +consider: GO:0005783 +consider: GO:0006874 + +[Term] +id: GO:0045785 +name: positive regulation of cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] +synonym: "activation of cell adhesion" NARROW [] +synonym: "stimulation of cell adhesion" NARROW [] +synonym: "up regulation of cell adhesion" EXACT [] +synonym: "up-regulation of cell adhesion" EXACT [] +synonym: "upregulation of cell adhesion" EXACT [] +is_a: GO:0030155 ! regulation of cell adhesion +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0007155 ! cell adhesion +relationship: positively_regulates GO:0007155 ! cell adhesion + +[Term] +id: GO:0045786 +name: negative regulation of cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of progression through cell cycle" EXACT [] +synonym: "down-regulation of progression through cell cycle" EXACT [] +synonym: "downregulation of progression through cell cycle" EXACT [] +synonym: "inhibition of progression through cell cycle" NARROW [] +synonym: "negative regulation of cell cycle progression" EXACT [] +synonym: "negative regulation of progression through cell cycle" EXACT [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007049 ! cell cycle +relationship: negatively_regulates GO:0007049 ! cell cycle + +[Term] +id: GO:0045787 +name: positive regulation of cell cycle +namespace: biological_process +def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] +synonym: "activation of progression through cell cycle" NARROW [] +synonym: "positive regulation of cell cycle progression" EXACT [] +synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of progression through cell cycle" NARROW [] +synonym: "up regulation of progression through cell cycle" EXACT [] +synonym: "up-regulation of progression through cell cycle" EXACT [] +synonym: "upregulation of progression through cell cycle" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007049 ! cell cycle +relationship: positively_regulates GO:0007049 ! cell cycle + +[Term] +id: GO:0045792 +name: negative regulation of cell size +namespace: biological_process +def: "Any process that reduces cell size." [GOC:go_curators] +synonym: "down regulation of cell size" EXACT [] +synonym: "down-regulation of cell size" EXACT [] +synonym: "downregulation of cell size" EXACT [] +synonym: "inhibition of cell size" NARROW [] +is_a: GO:0008361 ! regulation of cell size + +[Term] +id: GO:0045793 +name: positive regulation of cell size +namespace: biological_process +def: "Any process that increases cell size." [GOC:go_curators] +synonym: "activation of cell size" NARROW [] +synonym: "stimulation of cell size" NARROW [] +synonym: "up regulation of cell size" EXACT [] +synonym: "up-regulation of cell size" EXACT [] +synonym: "upregulation of cell size" EXACT [] +is_a: GO:0008361 ! regulation of cell size + +[Term] +id: GO:0045794 +name: negative regulation of cell volume +namespace: biological_process +def: "Any process that decreases cell volume." [GOC:go_curators] +synonym: "cell regulatory volume decrease" RELATED [PMID:12388065] +synonym: "RVD" RELATED [PMID:12388065] +is_a: GO:0006884 ! cell volume homeostasis + +[Term] +id: GO:0045795 +name: positive regulation of cell volume +namespace: biological_process +def: "Any process that increases cell volume." [GOC:go_curators] +is_a: GO:0006884 ! cell volume homeostasis + +[Term] +id: GO:0045796 +name: negative regulation of intestinal cholesterol absorption +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine." [GOC:go_curators] +synonym: "down regulation of cholesterol absorption" EXACT [] +synonym: "down-regulation of cholesterol absorption" EXACT [] +synonym: "downregulation of cholesterol absorption" EXACT [] +synonym: "inhibition of cholesterol absorption" NARROW [] +is_a: GO:0030300 ! regulation of intestinal cholesterol absorption +is_a: GO:0032375 ! negative regulation of cholesterol transport +is_a: GO:1904730 ! negative regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030299 ! intestinal cholesterol absorption +relationship: negatively_regulates GO:0030299 ! intestinal cholesterol absorption + +[Term] +id: GO:0045797 +name: positive regulation of intestinal cholesterol absorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine." [GOC:go_curators] +synonym: "activation of cholesterol absorption" NARROW [] +synonym: "stimulation of cholesterol absorption" NARROW [] +synonym: "up regulation of cholesterol absorption" EXACT [] +synonym: "up-regulation of cholesterol absorption" EXACT [] +synonym: "upregulation of cholesterol absorption" EXACT [] +is_a: GO:0030300 ! regulation of intestinal cholesterol absorption +is_a: GO:0032376 ! positive regulation of cholesterol transport +is_a: GO:1904731 ! positive regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030299 ! intestinal cholesterol absorption +relationship: positively_regulates GO:0030299 ! intestinal cholesterol absorption + +[Term] +id: GO:0045798 +name: negative regulation of chromatin assembly or disassembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] +synonym: "down regulation of chromatin assembly or disassembly" EXACT [] +synonym: "down-regulation of chromatin assembly or disassembly" EXACT [] +synonym: "downregulation of chromatin assembly or disassembly" EXACT [] +synonym: "inhibition of chromatin assembly or disassembly" NARROW [] +synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] +is_a: GO:0001672 ! regulation of chromatin assembly or disassembly +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006333 ! chromatin assembly or disassembly +relationship: negatively_regulates GO:0006333 ! chromatin assembly or disassembly + +[Term] +id: GO:0045799 +name: positive regulation of chromatin assembly or disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] +synonym: "activation of chromatin assembly or disassembly" NARROW [] +synonym: "positive regulation of chromatin assembly/disassembly" EXACT [] +synonym: "stimulation of chromatin assembly or disassembly" NARROW [] +synonym: "up regulation of chromatin assembly or disassembly" EXACT [] +synonym: "up-regulation of chromatin assembly or disassembly" EXACT [] +synonym: "upregulation of chromatin assembly or disassembly" EXACT [] +is_a: GO:0001672 ! regulation of chromatin assembly or disassembly +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006333 ! chromatin assembly or disassembly +relationship: positively_regulates GO:0006333 ! chromatin assembly or disassembly + +[Term] +id: GO:0045800 +name: negative regulation of chitin-based cuticle tanning +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning." [GOC:go_curators, GOC:jid, GOC:mtg_sensu] +synonym: "down regulation of cuticle tanning" EXACT [] +synonym: "down-regulation of cuticle tanning" EXACT [] +synonym: "downregulation of cuticle tanning" EXACT [] +synonym: "inhibition of cuticle tanning" NARROW [] +synonym: "negative regulation of cuticle hardening" NARROW [] +synonym: "negative regulation of cuticle tanning" EXACT [] +is_a: GO:0007564 ! regulation of chitin-based cuticle tanning +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007593 ! chitin-based cuticle sclerotization +relationship: negatively_regulates GO:0007593 ! chitin-based cuticle sclerotization + +[Term] +id: GO:0045801 +name: positive regulation of chitin-based cuticle tanning +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning." [GOC:go_curators, GOC:jid, GOC:mtg_sensu] +synonym: "activation of cuticle tanning" NARROW [] +synonym: "positive regulation of cuticle hardening" NARROW [] +synonym: "positive regulation of cuticle tanning" EXACT [] +synonym: "stimulation of cuticle tanning" NARROW [] +synonym: "up regulation of cuticle tanning" EXACT [] +synonym: "up-regulation of cuticle tanning" EXACT [] +synonym: "upregulation of cuticle tanning" EXACT [] +is_a: GO:0007564 ! regulation of chitin-based cuticle tanning +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007593 ! chitin-based cuticle sclerotization +relationship: positively_regulates GO:0007593 ! chitin-based cuticle sclerotization + +[Term] +id: GO:0045802 +name: obsolete negative regulation of cytoskeleton +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton." [GOC:go_curators] +comment: This term was made obsolete because cytoskeleton is not a process, so the term made no sense. +synonym: "negative regulation of cytoskeleton" EXACT [] +is_obsolete: true +consider: GO:0007010 + +[Term] +id: GO:0045803 +name: obsolete positive regulation of cytoskeleton +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton." [GOC:go_curators] +comment: This term was made obsolete because cytoskeleton is not a process, so the term made no sense. +synonym: "positive regulation of cytoskeleton" EXACT [] +is_obsolete: true +consider: GO:0007010 + +[Term] +id: GO:0045804 +name: negative regulation of eclosion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion." [GOC:go_curators] +synonym: "down regulation of eclosion" EXACT [] +synonym: "down-regulation of eclosion" EXACT [] +synonym: "downregulation of eclosion" EXACT [] +synonym: "inhibition of eclosion" NARROW [] +is_a: GO:0007563 ! regulation of eclosion +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007562 ! eclosion +relationship: negatively_regulates GO:0007562 ! eclosion + +[Term] +id: GO:0045805 +name: positive regulation of eclosion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eclosion." [GOC:go_curators] +synonym: "activation of eclosion" NARROW [] +synonym: "stimulation of eclosion" NARROW [] +synonym: "up regulation of eclosion" EXACT [] +synonym: "up-regulation of eclosion" EXACT [] +synonym: "upregulation of eclosion" EXACT [] +is_a: GO:0007563 ! regulation of eclosion +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007562 ! eclosion +relationship: positively_regulates GO:0007562 ! eclosion + +[Term] +id: GO:0045806 +name: negative regulation of endocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators] +synonym: "down regulation of endocytosis" EXACT [] +synonym: "down-regulation of endocytosis" EXACT [] +synonym: "downregulation of endocytosis" EXACT [] +synonym: "inhibition of endocytosis" NARROW [] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006897 ! endocytosis +relationship: negatively_regulates GO:0006897 ! endocytosis + +[Term] +id: GO:0045807 +name: positive regulation of endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators] +synonym: "activation of endocytosis" NARROW [] +synonym: "stimulation of endocytosis" NARROW [] +synonym: "up regulation of endocytosis" EXACT [] +synonym: "up-regulation of endocytosis" EXACT [] +synonym: "upregulation of endocytosis" EXACT [] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051130 ! positive regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006897 ! endocytosis +relationship: positively_regulates GO:0006897 ! endocytosis + +[Term] +id: GO:0045808 +name: negative regulation of establishment of competence for transformation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation." [GOC:go_curators] +synonym: "down regulation of establishment of competence for transformation" EXACT [] +synonym: "down-regulation of establishment of competence for transformation" EXACT [] +synonym: "downregulation of establishment of competence for transformation" EXACT [] +synonym: "inhibition of establishment of competence for transformation" NARROW [] +synonym: "inhibitor of the establishment of competence for transformation activity" RELATED [] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032105 ! negative regulation of response to extracellular stimulus +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0045304 ! regulation of establishment of competence for transformation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030420 ! establishment of competence for transformation +relationship: negatively_regulates GO:0030420 ! establishment of competence for transformation + +[Term] +id: GO:0045809 +name: positive regulation of establishment of competence for transformation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation." [GOC:go_curators] +synonym: "activation of establishment of competence for transformation" NARROW [] +synonym: "activator of the establishment of competence for transformation activity" RELATED [] +synonym: "stimulation of establishment of competence for transformation" NARROW [] +synonym: "up regulation of establishment of competence for transformation" EXACT [] +synonym: "up-regulation of establishment of competence for transformation" EXACT [] +synonym: "upregulation of establishment of competence for transformation" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0032106 ! positive regulation of response to extracellular stimulus +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0045304 ! regulation of establishment of competence for transformation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030420 ! establishment of competence for transformation +relationship: positively_regulates GO:0030420 ! establishment of competence for transformation + +[Term] +id: GO:0045812 +name: negative regulation of Wnt signaling pathway, calcium modulating pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "down-regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "downregulation of frizzled-2 signaling pathway" EXACT [] +synonym: "inhibition of frizzled-2 signaling pathway" NARROW [] +synonym: "negative regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "negative regulation of frizzled-2 signalling pathway" EXACT [] +synonym: "negative regulation of Wnt receptor signaling pathway, calcium modulating pathway" EXACT [] +synonym: "negative regulation of Wnt-activated signaling pathway, calcium modulating pathway" EXACT [GOC:signaling] +is_a: GO:0008591 ! regulation of Wnt signaling pathway, calcium modulating pathway +is_a: GO:2000051 ! negative regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway +relationship: negatively_regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway + +[Term] +id: GO:0045813 +name: positive regulation of Wnt signaling pathway, calcium modulating pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:go_curators] +synonym: "activation of frizzled-2 signaling pathway" NARROW [] +synonym: "positive regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "positive regulation of frizzled-2 signalling pathway" EXACT [] +synonym: "positive regulation of Wnt receptor signaling pathway, calcium modulating pathway" EXACT [] +synonym: "positive regulation of Wnt-activated signaling pathway, calcium modulating pathway" EXACT [GOC:signaling] +synonym: "stimulation of frizzled-2 signaling pathway" NARROW [] +synonym: "up regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "up-regulation of frizzled-2 signaling pathway" EXACT [] +synonym: "upregulation of frizzled-2 signaling pathway" EXACT [] +is_a: GO:0008591 ! regulation of Wnt signaling pathway, calcium modulating pathway +is_a: GO:2000052 ! positive regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway +relationship: positively_regulates GO:0007223 ! Wnt signaling pathway, calcium modulating pathway + +[Term] +id: GO:0045814 +name: negative regulation of gene expression, epigenetic +namespace: biological_process +def: "Any epigenetic process that stops, prevents or reduces the rate of gene expression." [GOC:go_curators] +synonym: "down regulation of gene expression, epigenetic" EXACT [] +synonym: "down-regulation of gene expression, epigenetic" EXACT [] +synonym: "downregulation of gene expression, epigenetic" EXACT [] +synonym: "inhibition of gene expression, epigenetic" NARROW [] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0040029 ! regulation of gene expression, epigenetic + +[Term] +id: GO:0045815 +name: positive regulation of gene expression, epigenetic +namespace: biological_process +def: "Any epigenetic process that activates or increases the rate of gene expression." [GOC:go_curators] +synonym: "activation of gene expression, epigenetic" NARROW [] +synonym: "stimulation of gene expression, epigenetic" NARROW [] +synonym: "up regulation of gene expression, epigenetic" EXACT [] +synonym: "up-regulation of gene expression, epigenetic" EXACT [] +synonym: "upregulation of gene expression, epigenetic" EXACT [] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0040029 ! regulation of gene expression, epigenetic + +[Term] +id: GO:0045818 +name: negative regulation of glycogen catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] +synonym: "down regulation of glycogen catabolic process" EXACT [] +synonym: "down-regulation of glycogen catabolic process" EXACT [] +synonym: "downregulation of glycogen catabolic process" EXACT [] +synonym: "inhibition of glycogen catabolic process" NARROW [] +synonym: "negative regulation of glycogen breakdown" EXACT [] +synonym: "negative regulation of glycogen catabolism" EXACT [] +synonym: "negative regulation of glycogen degradation" EXACT [] +synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl] +is_a: GO:0005981 ! regulation of glycogen catabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0070874 ! negative regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005980 ! glycogen catabolic process +relationship: negatively_regulates GO:0005980 ! glycogen catabolic process + +[Term] +id: GO:0045819 +name: positive regulation of glycogen catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] +synonym: "activation of glycogen catabolic process" NARROW [] +synonym: "positive regulation of glycogen breakdown" EXACT [] +synonym: "positive regulation of glycogen catabolism" EXACT [] +synonym: "positive regulation of glycogen degradation" EXACT [] +synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl] +synonym: "stimulation of glycogen catabolic process" NARROW [] +synonym: "up regulation of glycogen catabolic process" EXACT [] +synonym: "up-regulation of glycogen catabolic process" EXACT [] +synonym: "upregulation of glycogen catabolic process" EXACT [] +is_a: GO:0005981 ! regulation of glycogen catabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0070875 ! positive regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005980 ! glycogen catabolic process +relationship: positively_regulates GO:0005980 ! glycogen catabolic process + +[Term] +id: GO:0045820 +name: negative regulation of glycolytic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis." [GOC:go_curators] +synonym: "down regulation of glycolysis" EXACT [] +synonym: "down-regulation of glycolysis" EXACT [] +synonym: "downregulation of glycolysis" EXACT [] +synonym: "inhibition of glycolysis" NARROW [] +is_a: GO:0006110 ! regulation of glycolytic process +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0042326 ! negative regulation of phosphorylation +is_a: GO:1900543 ! negative regulation of purine nucleotide metabolic process +is_a: GO:1903579 ! negative regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006096 ! glycolytic process +relationship: negatively_regulates GO:0006096 ! glycolytic process + +[Term] +id: GO:0045821 +name: positive regulation of glycolytic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycolysis." [GOC:go_curators] +synonym: "activation of glycolysis" NARROW [] +synonym: "stimulation of glycolysis" NARROW [] +synonym: "up regulation of glycolysis" EXACT [] +synonym: "up-regulation of glycolysis" EXACT [] +synonym: "upregulation of glycolysis" EXACT [] +is_a: GO:0006110 ! regulation of glycolytic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0042327 ! positive regulation of phosphorylation +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:1900544 ! positive regulation of purine nucleotide metabolic process +is_a: GO:1903580 ! positive regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006096 ! glycolytic process +relationship: positively_regulates GO:0006096 ! glycolytic process + +[Term] +id: GO:0045822 +name: negative regulation of heart contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators] +synonym: "down regulation of heart contraction" EXACT [] +synonym: "down-regulation of heart contraction" EXACT [] +synonym: "downregulation of heart contraction" EXACT [] +synonym: "inhibition of heart contraction" NARROW [] +synonym: "negative regulation of cardiac contraction" RELATED [] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:1903523 ! negative regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060047 ! heart contraction +relationship: negatively_regulates GO:0060047 ! heart contraction + +[Term] +id: GO:0045823 +name: positive regulation of heart contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators] +synonym: "activation of heart contraction" NARROW [] +synonym: "positive regulation of cardiac contraction" EXACT [] +synonym: "stimulation of heart contraction" NARROW [] +synonym: "up regulation of heart contraction" EXACT [] +synonym: "up-regulation of heart contraction" EXACT [] +synonym: "upregulation of heart contraction" EXACT [] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:1903524 ! positive regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060047 ! heart contraction +relationship: positively_regulates GO:0060047 ! heart contraction + +[Term] +id: GO:0045824 +name: negative regulation of innate immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response." [GOC:go_curators] +synonym: "down regulation of innate immune response" EXACT [] +synonym: "down-regulation of innate immune response" EXACT [] +synonym: "downregulation of innate immune response" EXACT [] +synonym: "inhibition of innate immune response" NARROW [] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0050777 ! negative regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045087 ! innate immune response +relationship: negatively_regulates GO:0045087 ! innate immune response + +[Term] +id: GO:0045825 +name: obsolete negative regulation of intermediate filament polymerization and/or depolymerization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization and/or depolymerization." [GOC:go_curators] +comment: This term was made obsolete because it has been split. +synonym: "negative regulation of intermediate filament polymerization and/or depolymerization" EXACT [] +is_obsolete: true +consider: GO:0030840 +consider: GO:0030843 + +[Term] +id: GO:0045826 +name: obsolete positive regulation of intermediate filament polymerization and/or depolymerization +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization and/or depolymerization." [GOC:go_curators] +comment: This term was made obsolete because it has been split. +synonym: "positive regulation of intermediate filament polymerization and/or depolymerization" EXACT [] +is_obsolete: true +consider: GO:0030841 +consider: GO:0030844 + +[Term] +id: GO:0045827 +name: negative regulation of isoprenoid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] +synonym: "down regulation of isoprenoid metabolic process" EXACT [] +synonym: "down-regulation of isoprenoid metabolic process" EXACT [] +synonym: "downregulation of isoprenoid metabolic process" EXACT [] +synonym: "inhibition of isoprenoid metabolic process" NARROW [] +synonym: "negative regulation of isoprenoid metabolism" EXACT [] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006720 ! isoprenoid metabolic process +relationship: negatively_regulates GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0045828 +name: positive regulation of isoprenoid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] +synonym: "activation of isoprenoid metabolic process" NARROW [] +synonym: "positive regulation of isoprenoid metabolism" EXACT [] +synonym: "stimulation of isoprenoid metabolic process" NARROW [] +synonym: "up regulation of isoprenoid metabolic process" EXACT [] +synonym: "up-regulation of isoprenoid metabolic process" EXACT [] +synonym: "upregulation of isoprenoid metabolic process" EXACT [] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006720 ! isoprenoid metabolic process +relationship: positively_regulates GO:0006720 ! isoprenoid metabolic process + +[Term] +id: GO:0045829 +name: negative regulation of isotype switching +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching." [GOC:go_curators] +synonym: "down regulation of isotype switching" EXACT [] +synonym: "down-regulation of isotype switching" EXACT [] +synonym: "downregulation of isotype switching" EXACT [] +synonym: "inhibition of isotype switching" NARROW [] +synonym: "negative regulation of class switch recombination" EXACT [] +synonym: "negative regulation of class switching" EXACT [] +synonym: "negative regulation of isotype switch recombination" EXACT [] +is_a: GO:0002638 ! negative regulation of immunoglobulin production +is_a: GO:0002890 ! negative regulation of immunoglobulin mediated immune response +is_a: GO:0045191 ! regulation of isotype switching +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:0050869 ! negative regulation of B cell activation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045190 ! isotype switching +relationship: negatively_regulates GO:0045190 ! isotype switching + +[Term] +id: GO:0045830 +name: positive regulation of isotype switching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isotype switching." [GOC:go_curators] +synonym: "activation of isotype switching" NARROW [] +synonym: "positive regulation of class switch recombination" EXACT [] +synonym: "positive regulation of class switching" EXACT [] +synonym: "positive regulation of isotype switch recombination" EXACT [] +synonym: "stimulation of isotype switching" NARROW [] +synonym: "up regulation of isotype switching" EXACT [] +synonym: "up-regulation of isotype switching" EXACT [] +synonym: "upregulation of isotype switching" EXACT [] +is_a: GO:0002639 ! positive regulation of immunoglobulin production +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +is_a: GO:0045191 ! regulation of isotype switching +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:0050871 ! positive regulation of B cell activation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045190 ! isotype switching +relationship: positively_regulates GO:0045190 ! isotype switching + +[Term] +id: GO:0045831 +name: negative regulation of light-activated channel activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity." [GOC:go_curators] +synonym: "down regulation of light-activated channel activity" EXACT [] +synonym: "down-regulation of light-activated channel activity" EXACT [] +synonym: "downregulation of light-activated channel activity" EXACT [] +synonym: "inhibition of light-activated channel activity" NARROW [] +is_a: GO:0016061 ! regulation of light-activated channel activity +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010461 ! light-activated ion channel activity +relationship: negatively_regulates GO:0010461 ! light-activated ion channel activity + +[Term] +id: GO:0045832 +name: positive regulation of light-activated channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of light-activated channel activity." [GOC:go_curators] +synonym: "activation of light-activated channel activity" NARROW [] +synonym: "stimulation of light-activated channel activity" NARROW [] +synonym: "up regulation of light-activated channel activity" EXACT [] +synonym: "up-regulation of light-activated channel activity" EXACT [] +synonym: "upregulation of light-activated channel activity" EXACT [] +is_a: GO:0016061 ! regulation of light-activated channel activity +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010461 ! light-activated ion channel activity +relationship: positively_regulates GO:0010461 ! light-activated ion channel activity + +[Term] +id: GO:0045833 +name: negative regulation of lipid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] +synonym: "down regulation of lipid metabolic process" EXACT [] +synonym: "down-regulation of lipid metabolic process" EXACT [] +synonym: "downregulation of lipid metabolic process" EXACT [] +synonym: "inhibition of lipid metabolic process" NARROW [] +synonym: "negative regulation of lipid metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006629 ! lipid metabolic process +relationship: negatively_regulates GO:0006629 ! lipid metabolic process + +[Term] +id: GO:0045834 +name: positive regulation of lipid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] +synonym: "activation of lipid metabolic process" NARROW [] +synonym: "positive regulation of lipid metabolism" EXACT [] +synonym: "stimulation of lipid metabolic process" NARROW [] +synonym: "up regulation of lipid metabolic process" EXACT [] +synonym: "up-regulation of lipid metabolic process" EXACT [] +synonym: "upregulation of lipid metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006629 ! lipid metabolic process +relationship: positively_regulates GO:0006629 ! lipid metabolic process + +[Term] +id: GO:0045835 +name: negative regulation of meiotic nuclear division +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] +synonym: "down regulation of meiosis" EXACT [] +synonym: "down-regulation of meiosis" EXACT [] +synonym: "downregulation of meiosis" EXACT [] +synonym: "inhibition of meiosis" NARROW [] +synonym: "negative regulation of meiosis" EXACT [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0040020 ! regulation of meiotic nuclear division +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:0051784 ! negative regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0140013 ! meiotic nuclear division +relationship: negatively_regulates GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0045836 +name: positive regulation of meiotic nuclear division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] +synonym: "activation of meiosis" NARROW [] +synonym: "positive regulation of meiosis" EXACT [] +synonym: "stimulation of meiosis" NARROW [] +synonym: "up regulation of meiosis" EXACT [] +synonym: "up-regulation of meiosis" EXACT [] +synonym: "upregulation of meiosis" EXACT [] +is_a: GO:0040020 ! regulation of meiotic nuclear division +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0051785 ! positive regulation of nuclear division +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0140013 ! meiotic nuclear division +relationship: positively_regulates GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0045837 +name: negative regulation of membrane potential +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:go_curators] +synonym: "down regulation of membrane potential" EXACT [] +synonym: "down-regulation of membrane potential" EXACT [] +synonym: "downregulation of membrane potential" EXACT [] +synonym: "inhibition of membrane potential" NARROW [] +synonym: "reduction of membrane potential" EXACT [GOC:rph] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0045838 +name: positive regulation of membrane potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:go_curators] +synonym: "activation of membrane potential" NARROW [] +synonym: "elevation of membrane potential" EXACT [GOC:rph] +synonym: "stimulation of membrane potential" NARROW [] +synonym: "up regulation of membrane potential" EXACT [] +synonym: "up-regulation of membrane potential" EXACT [] +synonym: "upregulation of membrane potential" EXACT [] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0045839 +name: negative regulation of mitotic nuclear division +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of mitosis" EXACT [] +synonym: "down-regulation of mitosis" EXACT [] +synonym: "downregulation of mitosis" EXACT [] +synonym: "inhibition of mitosis" NARROW [] +synonym: "negative regulation of mitosis" EXACT [] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:0051784 ! negative regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0140014 ! mitotic nuclear division +relationship: negatively_regulates GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0045840 +name: positive regulation of mitotic nuclear division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] +synonym: "activation of mitosis" NARROW [] +synonym: "mitogenic activity" NARROW [] +synonym: "positive regulation of mitosis" EXACT [] +synonym: "stimulation of mitosis" NARROW [] +synonym: "up regulation of mitosis" EXACT [] +synonym: "up-regulation of mitosis" EXACT [] +synonym: "upregulation of mitosis" EXACT [] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0051785 ! positive regulation of nuclear division +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0140014 ! mitotic nuclear division +relationship: positively_regulates GO:0140014 ! mitotic nuclear division + +[Term] +id: GO:0045841 +name: negative regulation of mitotic metaphase/anaphase transition +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." [GOC:go_curators] +synonym: "down regulation of mitotic metaphase/anaphase transition" EXACT [] +synonym: "down-regulation of mitotic metaphase/anaphase transition" EXACT [] +synonym: "downregulation of mitotic metaphase/anaphase transition" EXACT [] +synonym: "inhibition of mitotic metaphase/anaphase transition" NARROW [] +is_a: GO:0030071 ! regulation of mitotic metaphase/anaphase transition +is_a: GO:1901991 ! negative regulation of mitotic cell cycle phase transition +is_a: GO:1902100 ! negative regulation of metaphase/anaphase transition of cell cycle +is_a: GO:2000816 ! negative regulation of mitotic sister chromatid separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle +relationship: negatively_regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle + +[Term] +id: GO:0045842 +name: positive regulation of mitotic metaphase/anaphase transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." [GOC:go_curators] +synonym: "activation of mitotic metaphase/anaphase transition" NARROW [] +synonym: "stimulation of mitotic metaphase/anaphase transition" NARROW [] +synonym: "up regulation of mitotic metaphase/anaphase transition" EXACT [] +synonym: "up-regulation of mitotic metaphase/anaphase transition" EXACT [] +synonym: "upregulation of mitotic metaphase/anaphase transition" EXACT [] +is_a: GO:0030071 ! regulation of mitotic metaphase/anaphase transition +is_a: GO:1901970 ! positive regulation of mitotic sister chromatid separation +is_a: GO:1901992 ! positive regulation of mitotic cell cycle phase transition +is_a: GO:1902101 ! positive regulation of metaphase/anaphase transition of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle +relationship: positively_regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle + +[Term] +id: GO:0045843 +name: negative regulation of striated muscle tissue development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators] +synonym: "down regulation of striated muscle development" EXACT [] +synonym: "down-regulation of striated muscle development" EXACT [] +synonym: "downregulation of striated muscle development" EXACT [] +synonym: "inhibition of striated muscle development" NARROW [] +is_a: GO:0016202 ! regulation of striated muscle tissue development +is_a: GO:0048635 ! negative regulation of muscle organ development +is_a: GO:1901862 ! negative regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014706 ! striated muscle tissue development +relationship: negatively_regulates GO:0014706 ! striated muscle tissue development + +[Term] +id: GO:0045844 +name: positive regulation of striated muscle tissue development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators] +synonym: "activation of striated muscle development" NARROW [] +synonym: "stimulation of striated muscle development" NARROW [] +synonym: "up regulation of striated muscle development" EXACT [] +synonym: "up-regulation of striated muscle development" EXACT [] +synonym: "upregulation of striated muscle development" EXACT [] +is_a: GO:0016202 ! regulation of striated muscle tissue development +is_a: GO:0048636 ! positive regulation of muscle organ development +is_a: GO:1901863 ! positive regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014706 ! striated muscle tissue development +relationship: positively_regulates GO:0014706 ! striated muscle tissue development + +[Term] +id: GO:0045847 +name: negative regulation of nitrogen utilization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization." [GOC:go_curators] +synonym: "down regulation of nitrogen utilization" EXACT [] +synonym: "down-regulation of nitrogen utilization" EXACT [] +synonym: "downregulation of nitrogen utilization" EXACT [] +synonym: "inhibition of nitrogen utilization" NARROW [] +is_a: GO:0006808 ! regulation of nitrogen utilization +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019740 ! nitrogen utilization +relationship: negatively_regulates GO:0019740 ! nitrogen utilization + +[Term] +id: GO:0045848 +name: positive regulation of nitrogen utilization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nitrogen utilization." [GOC:go_curators] +synonym: "activation of nitrogen utilization" NARROW [] +synonym: "stimulation of nitrogen utilization" NARROW [] +synonym: "up regulation of nitrogen utilization" EXACT [] +synonym: "up-regulation of nitrogen utilization" EXACT [] +synonym: "upregulation of nitrogen utilization" EXACT [] +is_a: GO:0006808 ! regulation of nitrogen utilization +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019740 ! nitrogen utilization +relationship: positively_regulates GO:0019740 ! nitrogen utilization + +[Term] +id: GO:0045849 +name: negative regulation of nurse cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "down regulation of nurse cell apoptosis" EXACT [] +synonym: "down-regulation of nurse cell apoptosis" EXACT [] +synonym: "downregulation of nurse cell apoptosis" EXACT [] +synonym: "inhibition of nurse cell apoptosis" NARROW [] +synonym: "negative regulation of nurse cell apoptosis" NARROW [] +is_a: GO:0045477 ! regulation of nurse cell apoptotic process +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +is_a: GO:1905880 ! negative regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045476 ! nurse cell apoptotic process +relationship: negatively_regulates GO:0045476 ! nurse cell apoptotic process + +[Term] +id: GO:0045850 +name: positive regulation of nurse cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] +synonym: "activation of nurse cell apoptosis" NARROW [] +synonym: "positive regulation of nurse cell apoptosis" NARROW [] +synonym: "stimulation of nurse cell apoptosis" NARROW [] +synonym: "up regulation of nurse cell apoptosis" EXACT [] +synonym: "up-regulation of nurse cell apoptosis" EXACT [] +synonym: "upregulation of nurse cell apoptosis" EXACT [] +is_a: GO:0045477 ! regulation of nurse cell apoptotic process +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +is_a: GO:1905881 ! positive regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045476 ! nurse cell apoptotic process +relationship: positively_regulates GO:0045476 ! nurse cell apoptotic process + +[Term] +id: GO:0045851 +name: pH reduction +namespace: biological_process +def: "Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion." [GOC:go_curators] +synonym: "acidification" EXACT [] +is_a: GO:0006885 ! regulation of pH + +[Term] +id: GO:0045852 +name: pH elevation +namespace: biological_process +def: "Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion." [GOC:go_curators] +is_a: GO:0006885 ! regulation of pH + +[Term] +id: GO:0045853 +name: negative regulation of bicoid mRNA localization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location." [GOC:go_curators] +synonym: "down regulation of bicoid mRNA localization" EXACT [] +synonym: "down-regulation of bicoid mRNA localization" EXACT [] +synonym: "downregulation of bicoid mRNA localization" EXACT [] +synonym: "inhibition of bicoid mRNA localization" NARROW [] +synonym: "negative regulation of bicoid mRNA localisation" EXACT [GOC:mah] +is_a: GO:0008359 ! regulation of bicoid mRNA localization +is_a: GO:0060283 ! negative regulation of oocyte development +is_a: GO:1902876 ! negative regulation of embryonic pattern specification +is_a: GO:1903430 ! negative regulation of cell maturation +is_a: GO:1904581 ! negative regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045450 ! bicoid mRNA localization +relationship: negatively_regulates GO:0045450 ! bicoid mRNA localization + +[Term] +id: GO:0045854 +name: positive regulation of bicoid mRNA localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location." [GOC:go_curators] +synonym: "activation of bicoid mRNA localization" NARROW [] +synonym: "positive regulation of bicoid mRNA localisation" EXACT [GOC:mah] +synonym: "stimulation of bicoid mRNA localization" NARROW [] +synonym: "up regulation of bicoid mRNA localization" EXACT [] +synonym: "up-regulation of bicoid mRNA localization" EXACT [] +synonym: "upregulation of bicoid mRNA localization" EXACT [] +is_a: GO:0008359 ! regulation of bicoid mRNA localization +is_a: GO:0060282 ! positive regulation of oocyte development +is_a: GO:1902877 ! positive regulation of embryonic pattern specification +is_a: GO:1903431 ! positive regulation of cell maturation +is_a: GO:1904582 ! positive regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045450 ! bicoid mRNA localization +relationship: positively_regulates GO:0045450 ! bicoid mRNA localization + +[Term] +id: GO:0045855 +name: negative regulation of pole plasm oskar mRNA localization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm." [GOC:go_curators] +synonym: "down regulation of pole plasm oskar mRNA localization" EXACT [] +synonym: "down-regulation of pole plasm oskar mRNA localization" EXACT [] +synonym: "downregulation of pole plasm oskar mRNA localization" EXACT [] +synonym: "inhibition of pole plasm oskar mRNA localization" NARROW [] +synonym: "negative regulation of oocyte pole plasm oskar mRNA localization" EXACT [] +synonym: "negative regulation of pole plasm oskar mRNA localisation" EXACT [GOC:mah] +is_a: GO:0007317 ! regulation of pole plasm oskar mRNA localization +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0060283 ! negative regulation of oocyte development +is_a: GO:1902876 ! negative regulation of embryonic pattern specification +is_a: GO:1903430 ! negative regulation of cell maturation +is_a: GO:1904581 ! negative regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045451 ! pole plasm oskar mRNA localization +relationship: negatively_regulates GO:0045451 ! pole plasm oskar mRNA localization + +[Term] +id: GO:0045856 +name: positive regulation of pole plasm oskar mRNA localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm." [GOC:go_curators] +synonym: "activation of pole plasm oskar mRNA localization" NARROW [] +synonym: "positive regulation of oocyte pole plasm oskar mRNA localization" EXACT [] +synonym: "positive regulation of pole plasm oskar mRNA localisation" EXACT [GOC:mah] +synonym: "stimulation of pole plasm oskar mRNA localization" NARROW [] +synonym: "up regulation of pole plasm oskar mRNA localization" EXACT [] +synonym: "up-regulation of pole plasm oskar mRNA localization" EXACT [] +synonym: "upregulation of pole plasm oskar mRNA localization" EXACT [] +is_a: GO:0007317 ! regulation of pole plasm oskar mRNA localization +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0060282 ! positive regulation of oocyte development +is_a: GO:1902877 ! positive regulation of embryonic pattern specification +is_a: GO:1903431 ! positive regulation of cell maturation +is_a: GO:1904582 ! positive regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045451 ! pole plasm oskar mRNA localization +relationship: positively_regulates GO:0045451 ! pole plasm oskar mRNA localization + +[Term] +id: GO:0045857 +name: negative regulation of molecular function, epigenetic +namespace: biological_process +def: "Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of protein activity, epigenetic" EXACT [] +synonym: "down-regulation of protein activity, epigenetic" EXACT [] +synonym: "downregulation of protein activity, epigenetic" EXACT [] +synonym: "inhibition of protein activity, epigenetic" NARROW [] +synonym: "negative regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] +is_a: GO:0040030 ! regulation of molecular function, epigenetic +is_a: GO:0044092 ! negative regulation of molecular function + +[Term] +id: GO:0045858 +name: positive regulation of molecular function, epigenetic +namespace: biological_process +def: "Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of protein activity, epigenetic" NARROW [] +synonym: "positive regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of protein activity, epigenetic" NARROW [] +synonym: "up regulation of protein activity, epigenetic" EXACT [] +synonym: "up-regulation of protein activity, epigenetic" EXACT [] +synonym: "upregulation of protein activity, epigenetic" EXACT [] +is_a: GO:0040030 ! regulation of molecular function, epigenetic +is_a: GO:0044093 ! positive regulation of molecular function + +[Term] +id: GO:0045859 +name: regulation of protein kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein kinase activity." [GOC:go_curators] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004672 ! protein kinase activity +relationship: regulates GO:0004672 ! protein kinase activity + +[Term] +id: GO:0045860 +name: positive regulation of protein kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein kinase activity." [GOC:go_curators] +synonym: "stimulation of protein kinase activity" NARROW [] +synonym: "up regulation of protein kinase activity" EXACT [] +synonym: "up-regulation of protein kinase activity" EXACT [] +synonym: "upregulation of protein kinase activity" EXACT [] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0033674 ! positive regulation of kinase activity +is_a: GO:0045859 ! regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004672 ! protein kinase activity +relationship: positively_regulates GO:0004672 ! protein kinase activity + +[Term] +id: GO:0045861 +name: negative regulation of proteolysis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:go_curators] +synonym: "down regulation of proteolysis" EXACT [] +synonym: "down-regulation of proteolysis" EXACT [] +synonym: "downregulation of proteolysis" EXACT [] +synonym: "inhibition of proteolysis" NARROW [] +synonym: "negative regulation of peptidolysis" EXACT [] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:0032269 ! negative regulation of cellular protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006508 ! proteolysis +relationship: negatively_regulates GO:0006508 ! proteolysis + +[Term] +id: GO:0045862 +name: positive regulation of proteolysis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:go_curators] +synonym: "activation of proteolysis" NARROW [] +synonym: "positive regulation of peptidolysis" EXACT [] +synonym: "stimulation of proteolysis" NARROW [] +synonym: "up regulation of proteolysis" EXACT [] +synonym: "up-regulation of proteolysis" EXACT [] +synonym: "upregulation of proteolysis" EXACT [] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:0032270 ! positive regulation of cellular protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006508 ! proteolysis +relationship: positively_regulates GO:0006508 ! proteolysis + +[Term] +id: GO:0045863 +name: negative regulation of pteridine metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] +synonym: "down regulation of pteridine metabolic process" EXACT [] +synonym: "down-regulation of pteridine metabolic process" EXACT [] +synonym: "downregulation of pteridine metabolic process" EXACT [] +synonym: "inhibition of pteridine metabolic process" NARROW [] +synonym: "negative regulation of pteridine metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0042068 ! regulation of pteridine metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019889 ! pteridine metabolic process +relationship: negatively_regulates GO:0019889 ! pteridine metabolic process + +[Term] +id: GO:0045864 +name: positive regulation of pteridine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] +synonym: "activation of pteridine metabolic process" NARROW [] +synonym: "positive regulation of pteridine metabolism" EXACT [] +synonym: "stimulation of pteridine metabolic process" NARROW [] +synonym: "up regulation of pteridine metabolic process" EXACT [] +synonym: "up-regulation of pteridine metabolic process" EXACT [] +synonym: "upregulation of pteridine metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0042068 ! regulation of pteridine metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019889 ! pteridine metabolic process +relationship: positively_regulates GO:0019889 ! pteridine metabolic process + +[Term] +id: GO:0045865 +name: obsolete regulation of recombination within rDNA repeats +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA." [GOC:go_curators, ISBN:0198506732] +comment: This term was made obsolete because it describes a substrate-specific process. +synonym: "regulation of recombination within rDNA repeats" EXACT [] +is_obsolete: true +replaced_by: GO:0000019 + +[Term] +id: GO:0045866 +name: obsolete positive regulation of recombination within rDNA repeats +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA." [GOC:go_curators, ISBN:0198506732] +comment: This term was made obsolete because it describes a substrate-specific process. +synonym: "positive regulation of recombination within rDNA repeats" EXACT [] +is_obsolete: true +consider: GO:0045951 + +[Term] +id: GO:0045869 +name: negative regulation of single stranded viral RNA replication via double stranded DNA intermediate +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate." [GOC:go_curators] +synonym: "down regulation of retroviral genome replication" EXACT [] +synonym: "down-regulation of retroviral genome replication" EXACT [] +synonym: "downregulation of retroviral genome replication" EXACT [] +synonym: "inhibition of retroviral genome replication" NARROW [] +synonym: "negative regulation of retroviral genome replication" EXACT [GOC:bf, GOC:jl] +synonym: "regulation of retroviral genome replication" RELATED [] +is_a: GO:0045071 ! negative regulation of viral genome replication +is_a: GO:0045091 ! regulation of single stranded viral RNA replication via double stranded DNA intermediate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate +relationship: negatively_regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate + +[Term] +id: GO:0045870 +name: positive regulation of single stranded viral RNA replication via double stranded DNA intermediate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retroviral genome replication." [GOC:go_curators] +synonym: "activation of retroviral genome replication" NARROW [] +synonym: "positive regulation of retroviral genome replication" EXACT [GOC:bf, GOC:jl] +synonym: "stimulation of retroviral genome replication" NARROW [] +synonym: "up regulation of retroviral genome replication" EXACT [] +synonym: "up-regulation of retroviral genome replication" EXACT [] +synonym: "upregulation of retroviral genome replication" EXACT [] +is_a: GO:0045070 ! positive regulation of viral genome replication +is_a: GO:0045091 ! regulation of single stranded viral RNA replication via double stranded DNA intermediate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate +relationship: positively_regulates GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate + +[Term] +id: GO:0045871 +name: negative regulation of rhodopsin gene expression +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of rhodopsin gene activity" EXACT [] +synonym: "down-regulation of rhodopsin gene activity" EXACT [] +synonym: "downregulation of rhodopsin gene activity" EXACT [] +synonym: "inhibition of rhodopsin gene activity" NARROW [] +synonym: "negative regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007468 ! regulation of rhodopsin gene expression +is_a: GO:0010629 ! negative regulation of gene expression + +[Term] +id: GO:0045872 +name: positive regulation of rhodopsin gene expression +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of rhodopsin gene activity" NARROW [] +synonym: "positive regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of rhodopsin gene activity" NARROW [] +synonym: "up regulation of rhodopsin gene activity" EXACT [] +synonym: "up-regulation of rhodopsin gene activity" EXACT [] +synonym: "upregulation of rhodopsin gene activity" EXACT [] +is_a: GO:0007468 ! regulation of rhodopsin gene expression +is_a: GO:0010628 ! positive regulation of gene expression + +[Term] +id: GO:0045873 +name: negative regulation of sevenless signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] +synonym: "down regulation of sevenless signaling pathway" EXACT [] +synonym: "down-regulation of sevenless signaling pathway" EXACT [] +synonym: "downregulation of sevenless signaling pathway" EXACT [] +synonym: "inhibition of sevenless signaling pathway" NARROW [] +synonym: "negative regulation of sev signaling pathway" EXACT [] +synonym: "negative regulation of sevenless signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0045501 ! regulation of sevenless signaling pathway +is_a: GO:0045677 ! negative regulation of R7 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045500 ! sevenless signaling pathway +relationship: negatively_regulates GO:0045500 ! sevenless signaling pathway + +[Term] +id: GO:0045874 +name: positive regulation of sevenless signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] +synonym: "activation of sevenless signaling pathway" NARROW [] +synonym: "positive regulation of sev signaling pathway" EXACT [] +synonym: "positive regulation of sevenless signalling pathway" EXACT [] +synonym: "stimulation of sevenless signaling pathway" NARROW [] +synonym: "up regulation of sevenless signaling pathway" EXACT [] +synonym: "up-regulation of sevenless signaling pathway" EXACT [] +synonym: "upregulation of sevenless signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:0045501 ! regulation of sevenless signaling pathway +is_a: GO:0045678 ! positive regulation of R7 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045500 ! sevenless signaling pathway +relationship: positively_regulates GO:0045500 ! sevenless signaling pathway + +[Term] +id: GO:0045875 +name: negative regulation of sister chromatid cohesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] +synonym: "down regulation of sister chromatid cohesion" EXACT [] +synonym: "down-regulation of sister chromatid cohesion" EXACT [] +synonym: "downregulation of sister chromatid cohesion" EXACT [] +synonym: "inhibition of sister chromatid cohesion" NARROW [] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +is_a: GO:0033046 ! negative regulation of sister chromatid segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007062 ! sister chromatid cohesion +relationship: negatively_regulates GO:0007062 ! sister chromatid cohesion + +[Term] +id: GO:0045876 +name: positive regulation of sister chromatid cohesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] +synonym: "activation of sister chromatid cohesion" NARROW [] +synonym: "stimulation of sister chromatid cohesion" NARROW [] +synonym: "up regulation of sister chromatid cohesion" EXACT [] +synonym: "up-regulation of sister chromatid cohesion" EXACT [] +synonym: "upregulation of sister chromatid cohesion" EXACT [] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +is_a: GO:0051984 ! positive regulation of chromosome segregation +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007062 ! sister chromatid cohesion +relationship: positively_regulates GO:0007062 ! sister chromatid cohesion + +[Term] +id: GO:0045879 +name: negative regulation of smoothened signaling pathway +namespace: biological_process +alt_id: GO:0045877 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling." [GOC:go_curators] +synonym: "down regulation of smoothened signaling pathway" EXACT [] +synonym: "down-regulation of smoothened signaling pathway" EXACT [] +synonym: "downregulation of smoothened signaling pathway" EXACT [] +synonym: "inhibition of smoothened signaling pathway" NARROW [] +synonym: "negative regulation of hedgehog signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "negative regulation of hh signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "negative regulation of smoothened activity" RELATED [] +synonym: "negative regulation of smoothened by patched" NARROW [] +synonym: "negative regulation of smoothened receptor activity by patched" RELATED [] +synonym: "negative regulation of smoothened signalling pathway" EXACT [] +is_a: GO:0008589 ! regulation of smoothened signaling pathway +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007224 ! smoothened signaling pathway +relationship: negatively_regulates GO:0007224 ! smoothened signaling pathway + +[Term] +id: GO:0045880 +name: positive regulation of smoothened signaling pathway +namespace: biological_process +alt_id: GO:0045878 +def: "Any process that activates or increases the frequency, rate or extent of smoothened signaling." [GOC:go_curators] +synonym: "activation of smoothened signaling pathway" NARROW [] +synonym: "positive regulation of hedgehog signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "positive regulation of hh signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "positive regulation of smoothened by patched" RELATED [] +synonym: "positive regulation of smoothened receptor activity by patched" RELATED [] +synonym: "positive regulation of smoothened signalling pathway" EXACT [] +synonym: "stimulation of smoothened signaling pathway" NARROW [] +synonym: "up regulation of smoothened signaling pathway" EXACT [] +synonym: "up-regulation of smoothened signaling pathway" EXACT [] +synonym: "upregulation of smoothened signaling pathway" EXACT [] +is_a: GO:0008589 ! regulation of smoothened signaling pathway +is_a: GO:0009967 ! positive regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007224 ! smoothened signaling pathway +relationship: positively_regulates GO:0007224 ! smoothened signaling pathway + +[Term] +id: GO:0045881 +name: positive regulation of sporulation resulting in formation of a cellular spore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sporulation." [GOC:go_curators] +synonym: "activation of sporulation" NARROW [] +synonym: "stimulation of sporulation" NARROW [] +synonym: "up regulation of sporulation" EXACT [] +synonym: "up-regulation of sporulation" EXACT [] +synonym: "upregulation of sporulation" EXACT [] +is_a: GO:0042173 ! regulation of sporulation resulting in formation of a cellular spore +is_a: GO:0043938 ! positive regulation of sporulation +is_a: GO:0045597 ! positive regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030435 ! sporulation resulting in formation of a cellular spore +relationship: positively_regulates GO:0030435 ! sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0045882 +name: negative regulation of sulfur utilization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization." [GOC:go_curators] +synonym: "down regulation of sulfur utilization" EXACT [] +synonym: "down-regulation of sulfur utilization" EXACT [] +synonym: "downregulation of sulfur utilization" EXACT [] +synonym: "inhibition of sulfur utilization" NARROW [] +synonym: "negative regulation of sulphur utilization" EXACT [] +is_a: GO:0006792 ! regulation of sulfur utilization +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006791 ! sulfur utilization +relationship: negatively_regulates GO:0006791 ! sulfur utilization + +[Term] +id: GO:0045883 +name: positive regulation of sulfur utilization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sulfur utilization." [GOC:go_curators] +synonym: "activation of sulfur utilization" NARROW [] +synonym: "positive regulation of sulphur utilization" EXACT [] +synonym: "stimulation of sulfur utilization" NARROW [] +synonym: "up regulation of sulfur utilization" EXACT [] +synonym: "up-regulation of sulfur utilization" EXACT [] +synonym: "upregulation of sulfur utilization" EXACT [] +is_a: GO:0006792 ! regulation of sulfur utilization +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006791 ! sulfur utilization +relationship: positively_regulates GO:0006791 ! sulfur utilization + +[Term] +id: GO:0045884 +name: obsolete regulation of survival gene product expression +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb] +comment: This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc. +synonym: "regulation of survival gene product activity" BROAD [GOC:dph, GOC:tb] +synonym: "regulation of survival gene product expression" EXACT [] +synonym: "regulation of survival gene products" BROAD [] +is_obsolete: true + +[Term] +id: GO:0045885 +name: obsolete positive regulation of survival gene product expression +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb] +comment: This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc. +synonym: "activation of survival gene product activity" BROAD [] +synonym: "positive regulation of survival gene product activity" BROAD [GOC:dph, GOC:tb] +synonym: "positive regulation of survival gene product expression" EXACT [] +synonym: "positive regulation of survival gene products" BROAD [] +synonym: "stimulation of survival gene product activity" NARROW [] +synonym: "up regulation of survival gene product activity" BROAD [] +synonym: "up-regulation of survival gene product activity" BROAD [] +synonym: "upregulation of survival gene product activity" BROAD [] +is_obsolete: true + +[Term] +id: GO:0045886 +name: negative regulation of synaptic growth at neuromuscular junction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] +synonym: "down regulation of synaptic growth at neuromuscular junction" EXACT [] +synonym: "down-regulation of synaptic growth at neuromuscular junction" EXACT [] +synonym: "downregulation of synaptic growth at neuromuscular junction" EXACT [] +synonym: "inhibition of synaptic growth at neuromuscular junction" NARROW [] +is_a: GO:0008582 ! regulation of synaptic growth at neuromuscular junction +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0051964 ! negative regulation of synapse assembly +is_a: GO:1904397 ! negative regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051124 ! synaptic growth at neuromuscular junction +relationship: negatively_regulates GO:0051124 ! synaptic growth at neuromuscular junction + +[Term] +id: GO:0045887 +name: positive regulation of synaptic growth at neuromuscular junction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] +synonym: "activation of synaptic growth at neuromuscular junction" NARROW [] +synonym: "stimulation of synaptic growth at neuromuscular junction" NARROW [] +synonym: "up regulation of synaptic growth at neuromuscular junction" EXACT [] +synonym: "up-regulation of synaptic growth at neuromuscular junction" EXACT [] +synonym: "upregulation of synaptic growth at neuromuscular junction" EXACT [] +is_a: GO:0008582 ! regulation of synaptic growth at neuromuscular junction +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0051965 ! positive regulation of synapse assembly +is_a: GO:1904398 ! positive regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051124 ! synaptic growth at neuromuscular junction +relationship: positively_regulates GO:0051124 ! synaptic growth at neuromuscular junction + +[Term] +id: GO:0045888 +name: obsolete regulation of transcription of homeotic gene (Polycomb group) +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the Polycomb group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "regulation of transcription of homeotic gene (Polycomb group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0045889 +name: obsolete positive regulation of transcription of homeotic gene (Polycomb group) +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "positive regulation of transcription of homeotic gene (Polycomb group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0045890 +name: obsolete regulation of transcription of homeotic gene (trithorax group) +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "regulation of transcription of homeotic gene (trithorax group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0045891 +name: obsolete negative regulation of transcription of homeotic gene (trithorax group) +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the trithorax group." [GOC:go_curators] +comment: This term was made obsolete because it relates to a specific gene family rather than a process. +synonym: "negative regulation of transcription of homeotic gene (trithorax group)" EXACT [] +is_obsolete: true +consider: GO:0006342 +consider: GO:0048096 + +[Term] +id: GO:0045892 +name: negative regulation of transcription, DNA-templated +namespace: biological_process +alt_id: GO:0016481 +alt_id: GO:0032582 +alt_id: GO:0061021 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "down regulation of gene-specific transcription" RELATED [] +synonym: "down regulation of transcription, DNA-dependent" EXACT [] +synonym: "down-regulation of gene-specific transcription" RELATED [] +synonym: "down-regulation of transcription, DNA-dependent" EXACT [] +synonym: "downregulation of gene-specific transcription" RELATED [] +synonym: "downregulation of transcription, DNA-dependent" EXACT [] +synonym: "inhibition of gene-specific transcription" RELATED [] +synonym: "inhibition of transcription, DNA-dependent" NARROW [] +synonym: "negative regulation of cellular transcription, DNA-dependent" EXACT [] +synonym: "negative regulation of gene-specific transcription" RELATED [] +synonym: "negative regulation of transcription, DNA-dependent" EXACT [GOC:txnOH] +synonym: "transcription repressor activity" RELATED [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:1903507 ! negative regulation of nucleic acid-templated transcription +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006351 ! transcription, DNA-templated +relationship: negatively_regulates GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0045893 +name: positive regulation of transcription, DNA-templated +namespace: biological_process +alt_id: GO:0043193 +alt_id: GO:0045941 +alt_id: GO:0061020 +def: "Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "activation of gene-specific transcription" RELATED [] +synonym: "activation of transcription, DNA-dependent" NARROW [] +synonym: "positive regulation of cellular transcription, DNA-dependent" EXACT [] +synonym: "positive regulation of gene-specific transcription" RELATED [] +synonym: "positive regulation of transcription, DNA-dependent" EXACT [GOC:txnOH] +synonym: "stimulation of gene-specific transcription" NARROW [] +synonym: "stimulation of transcription, DNA-dependent" NARROW [] +synonym: "transcription activator activity" RELATED [] +synonym: "up regulation of gene-specific transcription" RELATED [] +synonym: "up regulation of transcription, DNA-dependent" EXACT [] +synonym: "up-regulation of gene-specific transcription" RELATED [] +synonym: "up-regulation of transcription, DNA-dependent" EXACT [] +synonym: "upregulation of gene-specific transcription" RELATED [] +synonym: "upregulation of transcription, DNA-dependent" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:1903508 ! positive regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006351 ! transcription, DNA-templated +relationship: positively_regulates GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0045894 +name: negative regulation of mating-type specific transcription, DNA-templated +namespace: biological_process +def: "Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "down regulation of transcription, mating-type specific" EXACT [] +synonym: "down-regulation of transcription, mating-type specific" EXACT [] +synonym: "downregulation of transcription, mating-type specific" EXACT [] +synonym: "inhibition of transcription, mating-type specific" NARROW [] +synonym: "negative regulation of mating-type specific transcription, DNA-dependent" EXACT [GOC:txnOH] +is_a: GO:0007532 ! regulation of mating-type specific transcription, DNA-templated +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated + +[Term] +id: GO:0045895 +name: positive regulation of mating-type specific transcription, DNA-templated +namespace: biological_process +def: "Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] +synonym: "activation of transcription, mating-type specific" NARROW [] +synonym: "positive regulation of mating-type specific transcription, DNA-dependent" EXACT [GOC:txnOH] +synonym: "stimulation of transcription, mating-type specific" NARROW [] +synonym: "up regulation of transcription, mating-type specific" EXACT [] +synonym: "up-regulation of transcription, mating-type specific" EXACT [] +synonym: "upregulation of transcription, mating-type specific" EXACT [] +is_a: GO:0007532 ! regulation of mating-type specific transcription, DNA-templated +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated + +[Term] +id: GO:0045896 +name: obsolete regulation of transcription during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "mitotic regulation of transcription" EXACT [] +synonym: "regulation of transcription, mitotic" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0045897 +name: obsolete positive regulation of transcription during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "activation of transcription during mitosis" NARROW [GOC:mah] +synonym: "mitotic activation of transcription" EXACT [] +synonym: "positive regulation of transcription, mitotic" EXACT [GOC:mah] +synonym: "stimulation of transcription during mitosis" NARROW [GOC:mah] +synonym: "up regulation of transcription during mitosis" EXACT [GOC:mah] +synonym: "up-regulation of transcription during mitosis" EXACT [GOC:mah] +synonym: "upregulation of transcription during mitosis" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0045898 +name: regulation of RNA polymerase II transcription preinitiation complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly." [GOC:go_curators] +synonym: "regulation of RNA polymerase II transcriptional pre-initiation complex assembly" EXACT [] +synonym: "regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis" EXACT [] +synonym: "regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "regulation of RNA polymerase II transcriptional preinitiation complex formation" RELATED [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly +relationship: regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly + +[Term] +id: GO:0045899 +name: positive regulation of RNA polymerase II transcription preinitiation complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly." [GOC:go_curators] +synonym: "activation of RNA polymerase II transcriptional preinitiation complex assembly" NARROW [] +synonym: "positive regulation of RNA polymerase II transcriptional pre-initiation complex assembly" EXACT [] +synonym: "positive regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis" EXACT [] +synonym: "positive regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "positive regulation of RNA polymerase II transcriptional preinitiation complex formation" EXACT [] +synonym: "stimulation of RNA polymerase II transcriptional preinitiation complex assembly" NARROW [] +synonym: "up regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "up-regulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "upregulation of RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0045898 ! regulation of RNA polymerase II transcription preinitiation complex assembly +is_a: GO:0060261 ! positive regulation of transcription initiation from RNA polymerase II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly +relationship: positively_regulates GO:0051123 ! RNA polymerase II preinitiation complex assembly + +[Term] +id: GO:0045900 +name: negative regulation of translational elongation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] +synonym: "down regulation of translational elongation" EXACT [] +synonym: "down-regulation of translational elongation" EXACT [] +synonym: "downregulation of translational elongation" EXACT [] +synonym: "inhibition of translational elongation" NARROW [] +is_a: GO:0006448 ! regulation of translational elongation +is_a: GO:0017148 ! negative regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006414 ! translational elongation +relationship: negatively_regulates GO:0006414 ! translational elongation + +[Term] +id: GO:0045901 +name: positive regulation of translational elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] +synonym: "activation of translational elongation" NARROW [] +synonym: "stimulation of translational elongation" NARROW [] +synonym: "up regulation of translational elongation" EXACT [] +synonym: "up-regulation of translational elongation" EXACT [] +synonym: "upregulation of translational elongation" EXACT [] +is_a: GO:0006448 ! regulation of translational elongation +is_a: GO:0045727 ! positive regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006414 ! translational elongation +relationship: positively_regulates GO:0006414 ! translational elongation + +[Term] +id: GO:0045902 +name: negative regulation of translational fidelity +namespace: biological_process +def: "Any process that decreases the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] +synonym: "down regulation of translational fidelity" EXACT [] +synonym: "down-regulation of translational fidelity" EXACT [] +synonym: "downregulation of translational fidelity" EXACT [] +synonym: "inhibition of translational fidelity" NARROW [] +is_a: GO:0006450 ! regulation of translational fidelity +is_a: GO:0017148 ! negative regulation of translation + +[Term] +id: GO:0045903 +name: positive regulation of translational fidelity +namespace: biological_process +def: "Any process that increases the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] +synonym: "activation of translational fidelity" NARROW [] +synonym: "stimulation of translational fidelity" NARROW [] +synonym: "up regulation of translational fidelity" EXACT [] +synonym: "up-regulation of translational fidelity" EXACT [] +synonym: "upregulation of translational fidelity" EXACT [] +is_a: GO:0006450 ! regulation of translational fidelity +is_a: GO:0045727 ! positive regulation of translation + +[Term] +id: GO:0045904 +name: negative regulation of translational termination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] +synonym: "down regulation of translational termination" EXACT [] +synonym: "down-regulation of translational termination" EXACT [] +synonym: "downregulation of translational termination" EXACT [] +synonym: "inhibition of translational termination" NARROW [] +is_a: GO:0006449 ! regulation of translational termination +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006415 ! translational termination +relationship: negatively_regulates GO:0006415 ! translational termination + +[Term] +id: GO:0045905 +name: positive regulation of translational termination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] +synonym: "activation of translational termination" NARROW [] +synonym: "stimulation of translational termination" NARROW [] +synonym: "up regulation of translational termination" EXACT [] +synonym: "up-regulation of translational termination" EXACT [] +synonym: "upregulation of translational termination" EXACT [] +is_a: GO:0006449 ! regulation of translational termination +is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly +is_a: GO:0045727 ! positive regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006415 ! translational termination +relationship: positively_regulates GO:0006415 ! translational termination + +[Term] +id: GO:0045906 +name: negative regulation of vasoconstriction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction." [GOC:go_curators] +synonym: "down regulation of vasoconstriction" EXACT [] +synonym: "down-regulation of vasoconstriction" EXACT [] +synonym: "downregulation of vasoconstriction" EXACT [] +synonym: "inhibition of vasoconstriction" NARROW [] +is_a: GO:0019229 ! regulation of vasoconstriction +is_a: GO:0097755 ! positive regulation of blood vessel diameter +is_a: GO:1903523 ! negative regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042310 ! vasoconstriction +relationship: negatively_regulates GO:0042310 ! vasoconstriction + +[Term] +id: GO:0045907 +name: positive regulation of vasoconstriction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vasoconstriction." [GOC:go_curators] +synonym: "activation of vasoconstriction" NARROW [] +synonym: "stimulation of vasoconstriction" NARROW [] +synonym: "up regulation of vasoconstriction" EXACT [] +synonym: "up-regulation of vasoconstriction" EXACT [] +synonym: "upregulation of vasoconstriction" EXACT [] +is_a: GO:0019229 ! regulation of vasoconstriction +is_a: GO:1903524 ! positive regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042310 ! vasoconstriction +relationship: positively_regulates GO:0042310 ! vasoconstriction + +[Term] +id: GO:0045910 +name: negative regulation of DNA recombination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination." [GOC:go_curators] +synonym: "down regulation of DNA recombination" EXACT [] +synonym: "down-regulation of DNA recombination" EXACT [] +synonym: "downregulation of DNA recombination" EXACT [] +synonym: "inhibition of DNA recombination" NARROW [] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:0051053 ! negative regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006310 ! DNA recombination +relationship: negatively_regulates GO:0006310 ! DNA recombination + +[Term] +id: GO:0045911 +name: positive regulation of DNA recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA recombination." [GOC:go_curators] +synonym: "activation of DNA recombination" NARROW [] +synonym: "stimulation of DNA recombination" NARROW [] +synonym: "up regulation of DNA recombination" EXACT [] +synonym: "up-regulation of DNA recombination" EXACT [] +synonym: "upregulation of DNA recombination" EXACT [] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:0051054 ! positive regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006310 ! DNA recombination +relationship: positively_regulates GO:0006310 ! DNA recombination + +[Term] +id: GO:0045912 +name: negative regulation of carbohydrate metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] +synonym: "down regulation of carbohydrate metabolic process" EXACT [] +synonym: "down-regulation of carbohydrate metabolic process" EXACT [] +synonym: "downregulation of carbohydrate metabolic process" EXACT [] +synonym: "inhibition of carbohydrate metabolic process" NARROW [] +synonym: "negative regulation of carbohydrate metabolism" EXACT [] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0009892 ! negative regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005975 ! carbohydrate metabolic process +relationship: negatively_regulates GO:0005975 ! carbohydrate metabolic process + +[Term] +id: GO:0045913 +name: positive regulation of carbohydrate metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] +synonym: "activation of carbohydrate metabolic process" NARROW [] +synonym: "positive regulation of carbohydrate metabolism" EXACT [] +synonym: "stimulation of carbohydrate metabolic process" NARROW [] +synonym: "up regulation of carbohydrate metabolic process" EXACT [] +synonym: "up-regulation of carbohydrate metabolic process" EXACT [] +synonym: "upregulation of carbohydrate metabolic process" EXACT [] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +is_a: GO:0009893 ! positive regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005975 ! carbohydrate metabolic process +relationship: positively_regulates GO:0005975 ! carbohydrate metabolic process + +[Term] +id: GO:0045914 +name: negative regulation of catecholamine metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] +synonym: "down regulation of catecholamine metabolic process" EXACT [] +synonym: "down-regulation of catecholamine metabolic process" EXACT [] +synonym: "downregulation of catecholamine metabolic process" EXACT [] +synonym: "inhibition of catecholamine metabolic process" NARROW [] +synonym: "negative regulation of catecholamine metabolism" EXACT [] +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:0042069 ! regulation of catecholamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006584 ! catecholamine metabolic process +relationship: negatively_regulates GO:0006584 ! catecholamine metabolic process + +[Term] +id: GO:0045915 +name: positive regulation of catecholamine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] +synonym: "activation of catecholamine metabolic process" NARROW [] +synonym: "positive regulation of catecholamine metabolism" EXACT [] +synonym: "stimulation of catecholamine metabolic process" NARROW [] +synonym: "up regulation of catecholamine metabolic process" EXACT [] +synonym: "up-regulation of catecholamine metabolic process" EXACT [] +synonym: "upregulation of catecholamine metabolic process" EXACT [] +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:0042069 ! regulation of catecholamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006584 ! catecholamine metabolic process +relationship: positively_regulates GO:0006584 ! catecholamine metabolic process + +[Term] +id: GO:0045916 +name: negative regulation of complement activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation." [GOC:go_curators] +synonym: "down regulation of complement activation" EXACT [] +synonym: "down-regulation of complement activation" EXACT [] +synonym: "downregulation of complement activation" EXACT [] +synonym: "inhibition of complement activation" NARROW [] +synonym: "negative regulation of complement cascade" EXACT [GOC:add] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0002921 ! negative regulation of humoral immune response +is_a: GO:0030449 ! regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006956 ! complement activation +relationship: negatively_regulates GO:0006956 ! complement activation + +[Term] +id: GO:0045917 +name: positive regulation of complement activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation." [GOC:go_curators] +synonym: "activation of complement activation" NARROW [] +synonym: "positive regulation of complement cascade" EXACT [GOC:add] +synonym: "stimulation of complement activation" NARROW [] +synonym: "up regulation of complement activation" EXACT [] +synonym: "up-regulation of complement activation" EXACT [] +synonym: "upregulation of complement activation" EXACT [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0002922 ! positive regulation of humoral immune response +is_a: GO:0030449 ! regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006956 ! complement activation +relationship: positively_regulates GO:0006956 ! complement activation + +[Term] +id: GO:0045918 +name: negative regulation of cytolysis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis." [GOC:go_curators] +synonym: "down regulation of cytolysis" EXACT [] +synonym: "down-regulation of cytolysis" EXACT [] +synonym: "downregulation of cytolysis" EXACT [] +synonym: "inhibition of cytolysis" NARROW [] +is_a: GO:0042268 ! regulation of cytolysis +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019835 ! cytolysis +relationship: negatively_regulates GO:0019835 ! cytolysis + +[Term] +id: GO:0045919 +name: positive regulation of cytolysis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytolysis." [GOC:go_curators] +synonym: "activation of cytolysis" NARROW [] +synonym: "stimulation of cytolysis" NARROW [] +synonym: "up regulation of cytolysis" EXACT [] +synonym: "up-regulation of cytolysis" EXACT [] +synonym: "upregulation of cytolysis" EXACT [] +is_a: GO:0042268 ! regulation of cytolysis +is_a: GO:0048522 ! positive regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019835 ! cytolysis +relationship: positively_regulates GO:0019835 ! cytolysis + +[Term] +id: GO:0045920 +name: negative regulation of exocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators] +synonym: "down regulation of exocytosis" EXACT [] +synonym: "down-regulation of exocytosis" EXACT [] +synonym: "downregulation of exocytosis" EXACT [] +synonym: "inhibition of exocytosis" NARROW [] +is_a: GO:0017157 ! regulation of exocytosis +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006887 ! exocytosis +relationship: negatively_regulates GO:0006887 ! exocytosis + +[Term] +id: GO:0045921 +name: positive regulation of exocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators] +synonym: "activation of exocytosis" NARROW [] +synonym: "stimulation of exocytosis" NARROW [] +synonym: "up regulation of exocytosis" EXACT [] +synonym: "up-regulation of exocytosis" EXACT [] +synonym: "upregulation of exocytosis" EXACT [] +is_a: GO:0017157 ! regulation of exocytosis +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006887 ! exocytosis +relationship: positively_regulates GO:0006887 ! exocytosis + +[Term] +id: GO:0045922 +name: negative regulation of fatty acid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] +synonym: "down regulation of fatty acid metabolic process" EXACT [] +synonym: "down-regulation of fatty acid metabolic process" EXACT [] +synonym: "downregulation of fatty acid metabolic process" EXACT [] +synonym: "inhibition of fatty acid metabolic process" NARROW [] +synonym: "negative regulation of fatty acid metabolism" EXACT [] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006631 ! fatty acid metabolic process +relationship: negatively_regulates GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0045923 +name: positive regulation of fatty acid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] +synonym: "activation of fatty acid metabolic process" NARROW [] +synonym: "positive regulation of fatty acid metabolism" EXACT [] +synonym: "stimulation of fatty acid metabolic process" NARROW [] +synonym: "up regulation of fatty acid metabolic process" EXACT [] +synonym: "up-regulation of fatty acid metabolic process" EXACT [] +synonym: "upregulation of fatty acid metabolic process" EXACT [] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006631 ! fatty acid metabolic process +relationship: positively_regulates GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0045924 +name: regulation of female receptivity +namespace: biological_process +alt_id: GO:0060181 +def: "Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "female receptivity" RELATED [GOC:dph, GOC:tb] +is_a: GO:0060180 ! female mating behavior +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0045925 +name: positive regulation of female receptivity +namespace: biological_process +def: "Any process that activates or increases the receptiveness of a female to male advances." [GOC:go_curators] +synonym: "activation of female receptivity" NARROW [] +synonym: "stimulation of female receptivity" NARROW [] +synonym: "up regulation of female receptivity" EXACT [] +synonym: "up-regulation of female receptivity" EXACT [] +synonym: "upregulation of female receptivity" EXACT [] +is_a: GO:0045924 ! regulation of female receptivity + +[Term] +id: GO:0045926 +name: negative regulation of growth +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] +synonym: "down regulation of growth" EXACT [] +synonym: "down-regulation of growth" EXACT [] +synonym: "downregulation of growth" EXACT [] +synonym: "inhibition of growth" NARROW [] +is_a: GO:0040008 ! regulation of growth +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0040007 ! growth +relationship: negatively_regulates GO:0040007 ! growth + +[Term] +id: GO:0045927 +name: positive regulation of growth +namespace: biological_process +def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] +synonym: "activation of growth" NARROW [] +synonym: "stimulation of growth" NARROW [] +synonym: "up regulation of growth" EXACT [] +synonym: "up-regulation of growth" EXACT [] +synonym: "upregulation of growth" EXACT [] +is_a: GO:0040008 ! regulation of growth +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0040007 ! growth +relationship: positively_regulates GO:0040007 ! growth + +[Term] +id: GO:0045928 +name: negative regulation of juvenile hormone metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] +synonym: "down regulation of juvenile hormone metabolic process" EXACT [] +synonym: "down-regulation of juvenile hormone metabolic process" EXACT [] +synonym: "downregulation of juvenile hormone metabolic process" EXACT [] +synonym: "inhibition of juvenile hormone metabolic process" NARROW [] +synonym: "negative regulation of juvenile hormone metabolism" EXACT [] +is_a: GO:0007556 ! regulation of juvenile hormone metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006716 ! juvenile hormone metabolic process +relationship: negatively_regulates GO:0006716 ! juvenile hormone metabolic process + +[Term] +id: GO:0045929 +name: positive regulation of juvenile hormone metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] +synonym: "activation of juvenile hormone metabolic process" NARROW [] +synonym: "positive regulation of juvenile hormone metabolism" EXACT [] +synonym: "stimulation of juvenile hormone metabolic process" NARROW [] +synonym: "up regulation of juvenile hormone metabolic process" EXACT [] +synonym: "up-regulation of juvenile hormone metabolic process" EXACT [] +synonym: "upregulation of juvenile hormone metabolic process" EXACT [] +is_a: GO:0007556 ! regulation of juvenile hormone metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006716 ! juvenile hormone metabolic process +relationship: positively_regulates GO:0006716 ! juvenile hormone metabolic process + +[Term] +id: GO:0045930 +name: negative regulation of mitotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of progression through mitotic cell cycle" EXACT [] +synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] +synonym: "downregulation of progression through mitotic cell cycle" EXACT [] +synonym: "inhibition of progression through mitotic cell cycle" NARROW [] +synonym: "negative regulation of mitotic cell cycle progression" EXACT [] +synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0045786 ! negative regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000278 ! mitotic cell cycle +relationship: negatively_regulates GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0045931 +name: positive regulation of mitotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of progression through mitotic cell cycle" NARROW [] +synonym: "positive regulation of mitotic cell cycle progression" EXACT [] +synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of progression through mitotic cell cycle" NARROW [] +synonym: "up regulation of progression through mitotic cell cycle" EXACT [] +synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] +synonym: "upregulation of progression through mitotic cell cycle" EXACT [] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0045787 ! positive regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000278 ! mitotic cell cycle +relationship: positively_regulates GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0045932 +name: negative regulation of muscle contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators] +synonym: "down regulation of muscle contraction" EXACT [] +synonym: "down-regulation of muscle contraction" EXACT [] +synonym: "downregulation of muscle contraction" EXACT [] +synonym: "inhibition of muscle contraction" NARROW [] +is_a: GO:0006937 ! regulation of muscle contraction +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006936 ! muscle contraction +relationship: negatively_regulates GO:0006936 ! muscle contraction + +[Term] +id: GO:0045933 +name: positive regulation of muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators] +synonym: "activation of muscle contraction" NARROW [] +synonym: "stimulation of muscle contraction" NARROW [] +synonym: "up regulation of muscle contraction" EXACT [] +synonym: "up-regulation of muscle contraction" EXACT [] +synonym: "upregulation of muscle contraction" EXACT [] +is_a: GO:0006937 ! regulation of muscle contraction +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006936 ! muscle contraction +relationship: positively_regulates GO:0006936 ! muscle contraction + +[Term] +id: GO:0045934 +name: negative regulation of nucleobase-containing compound metabolic process +namespace: biological_process +def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] +synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] +synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process +relationship: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process + +[Term] +id: GO:0045935 +name: positive regulation of nucleobase-containing compound metabolic process +namespace: biological_process +def: "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] +synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] +synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] +synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] +synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process +relationship: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process + +[Term] +id: GO:0045936 +name: negative regulation of phosphate metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] +synonym: "down regulation of phosphate metabolic process" EXACT [] +synonym: "down-regulation of phosphate metabolic process" EXACT [] +synonym: "downregulation of phosphate metabolic process" EXACT [] +synonym: "inhibition of phosphate metabolic process" NARROW [] +synonym: "negative regulation of phosphate metabolism" EXACT [] +is_a: GO:0010563 ! negative regulation of phosphorus metabolic process +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process +relationship: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process + +[Term] +id: GO:0045937 +name: positive regulation of phosphate metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] +synonym: "activation of phosphate metabolic process" NARROW [] +synonym: "positive regulation of phosphate metabolism" EXACT [] +synonym: "stimulation of phosphate metabolic process" NARROW [] +synonym: "up regulation of phosphate metabolic process" EXACT [] +synonym: "up-regulation of phosphate metabolic process" EXACT [] +synonym: "upregulation of phosphate metabolic process" EXACT [] +is_a: GO:0010562 ! positive regulation of phosphorus metabolic process +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process +relationship: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process + +[Term] +id: GO:0045938 +name: positive regulation of circadian sleep/wake cycle, sleep +namespace: biological_process +def: "Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals." [GOC:go_curators] +synonym: "activation of circadian sleep/wake cycle, sleep" NARROW [] +synonym: "positive regulation of sleep" EXACT [] +synonym: "stimulation of circadian sleep/wake cycle, sleep" NARROW [] +synonym: "up regulation of circadian sleep/wake cycle, sleep" EXACT [] +synonym: "up-regulation of circadian sleep/wake cycle, sleep" EXACT [] +synonym: "upregulation of circadian sleep/wake cycle, sleep" EXACT [] +is_a: GO:0042753 ! positive regulation of circadian rhythm +is_a: GO:0045187 ! regulation of circadian sleep/wake cycle, sleep +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050802 ! circadian sleep/wake cycle, sleep +relationship: positively_regulates GO:0050802 ! circadian sleep/wake cycle, sleep + +[Term] +id: GO:0045939 +name: negative regulation of steroid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] +synonym: "down regulation of steroid metabolic process" EXACT [] +synonym: "down-regulation of steroid metabolic process" EXACT [] +synonym: "downregulation of steroid metabolic process" EXACT [] +synonym: "inhibition of steroid metabolic process" NARROW [] +synonym: "negative regulation of steroid metabolism" EXACT [] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008202 ! steroid metabolic process +relationship: negatively_regulates GO:0008202 ! steroid metabolic process + +[Term] +id: GO:0045940 +name: positive regulation of steroid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] +synonym: "activation of steroid metabolic process" NARROW [] +synonym: "positive regulation of steroid metabolism" EXACT [] +synonym: "stimulation of steroid metabolic process" NARROW [] +synonym: "up regulation of steroid metabolic process" EXACT [] +synonym: "up-regulation of steroid metabolic process" EXACT [] +synonym: "upregulation of steroid metabolic process" EXACT [] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008202 ! steroid metabolic process +relationship: positively_regulates GO:0008202 ! steroid metabolic process + +[Term] +id: GO:0045942 +name: negative regulation of phosphorus utilization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] +synonym: "down regulation of phosphorus utilization" EXACT [] +synonym: "down-regulation of phosphorus utilization" EXACT [] +synonym: "downregulation of phosphorus utilization" EXACT [] +synonym: "inhibition of phosphorus utilization" NARROW [] +is_a: GO:0006795 ! regulation of phosphorus utilization +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006794 ! phosphorus utilization +relationship: negatively_regulates GO:0006794 ! phosphorus utilization + +[Term] +id: GO:0045943 +name: positive regulation of transcription by RNA polymerase I +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I." [GOC:go_curators, GOC:txnOH] +synonym: "activation of transcription from RNA polymerase I promoter" NARROW [] +synonym: "positive regulation of transcription from Pol I promoter" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "stimulation of transcription from RNA polymerase I promoter" NARROW [] +synonym: "up regulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "up-regulation of transcription from RNA polymerase I promoter" EXACT [] +synonym: "upregulation of transcription from RNA polymerase I promoter" EXACT [] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006360 ! transcription by RNA polymerase I +relationship: positively_regulates GO:0006360 ! transcription by RNA polymerase I + +[Term] +id: GO:0045944 +name: positive regulation of transcription by RNA polymerase II +namespace: biological_process +alt_id: GO:0010552 +alt_id: GO:0045817 +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] +synonym: "activation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "activation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [] +synonym: "positive regulation of global transcription from Pol II promoter" RELATED [] +synonym: "positive regulation of transcription from Pol II promoter" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global" RELATED [] +synonym: "stimulation of global transcription from RNA polymerase II promoter" NARROW [] +synonym: "stimulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "up regulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "up regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "up-regulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "up-regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "upregulation of global transcription from RNA polymerase II promoter" RELATED [] +synonym: "upregulation of transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006366 ! transcription by RNA polymerase II +relationship: positively_regulates GO:0006366 ! transcription by RNA polymerase II + +[Term] +id: GO:0045945 +name: positive regulation of transcription by RNA polymerase III +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III." [GOC:go_curators, GOC:txnOH] +synonym: "activation of transcription from RNA polymerase III promoter" NARROW [] +synonym: "positive regulation of transcription from Pol III promoter" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "stimulation of transcription from RNA polymerase III promoter" NARROW [] +synonym: "up regulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "up-regulation of transcription from RNA polymerase III promoter" EXACT [] +synonym: "upregulation of transcription from RNA polymerase III promoter" EXACT [] +is_a: GO:0006359 ! regulation of transcription by RNA polymerase III +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006383 ! transcription by RNA polymerase III +relationship: positively_regulates GO:0006383 ! transcription by RNA polymerase III + +[Term] +id: GO:0045947 +name: negative regulation of translational initiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] +synonym: "down regulation of translational initiation" EXACT [] +synonym: "down-regulation of translational initiation" EXACT [] +synonym: "downregulation of translational initiation" EXACT [] +synonym: "inhibition of translational initiation" NARROW [] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0017148 ! negative regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006413 ! translational initiation +relationship: negatively_regulates GO:0006413 ! translational initiation + +[Term] +id: GO:0045948 +name: positive regulation of translational initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] +synonym: "activation of translational initiation" NARROW [] +synonym: "stimulation of translational initiation" NARROW [] +synonym: "up regulation of translational initiation" EXACT [] +synonym: "up-regulation of translational initiation" EXACT [] +synonym: "upregulation of translational initiation" EXACT [] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0045727 ! positive regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006413 ! translational initiation +relationship: positively_regulates GO:0006413 ! translational initiation + +[Term] +id: GO:0045949 +name: positive regulation of phosphorus utilization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] +synonym: "activation of phosphorus utilization" NARROW [] +synonym: "stimulation of phosphorus utilization" NARROW [] +synonym: "up regulation of phosphorus utilization" EXACT [] +synonym: "up-regulation of phosphorus utilization" EXACT [] +synonym: "upregulation of phosphorus utilization" EXACT [] +is_a: GO:0006795 ! regulation of phosphorus utilization +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006794 ! phosphorus utilization +relationship: positively_regulates GO:0006794 ! phosphorus utilization + +[Term] +id: GO:0045950 +name: negative regulation of mitotic recombination +namespace: biological_process +def: "Any process that inhibits or decreases the rate of DNA recombination during mitosis." [GOC:go_curators, GOC:hjd] +synonym: "down regulation of mitotic recombination" EXACT [] +synonym: "down-regulation of mitotic recombination" EXACT [] +synonym: "downregulation of mitotic recombination" EXACT [] +synonym: "inhibition of mitotic recombination" NARROW [] +synonym: "negative regulation of recombination within rDNA repeats" NARROW [] +is_a: GO:0000019 ! regulation of mitotic recombination +is_a: GO:0045910 ! negative regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006312 ! mitotic recombination +relationship: negatively_regulates GO:0006312 ! mitotic recombination + +[Term] +id: GO:0045951 +name: positive regulation of mitotic recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis." [GOC:go_curators] +synonym: "activation of mitotic recombination" NARROW [] +synonym: "positive regulation of recombination within rDNA repeats" NARROW [] +synonym: "stimulation of mitotic recombination" NARROW [] +synonym: "up regulation of mitotic recombination" EXACT [] +synonym: "up-regulation of mitotic recombination" EXACT [] +synonym: "upregulation of mitotic recombination" EXACT [] +is_a: GO:0000019 ! regulation of mitotic recombination +is_a: GO:0045911 ! positive regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006312 ! mitotic recombination +relationship: positively_regulates GO:0006312 ! mitotic recombination + +[Term] +id: GO:0045952 +name: regulation of juvenile hormone catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] +synonym: "regulation of juvenile hormone breakdown" EXACT [] +synonym: "regulation of juvenile hormone catabolism" EXACT [] +synonym: "regulation of juvenile hormone degradation" EXACT [] +is_a: GO:0007556 ! regulation of juvenile hormone metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006719 ! juvenile hormone catabolic process +relationship: regulates GO:0006719 ! juvenile hormone catabolic process + +[Term] +id: GO:0045953 +name: negative regulation of natural killer cell mediated cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "down regulation of natural killer cell mediated cytotoxicity" EXACT [] +synonym: "down-regulation of natural killer cell mediated cytotoxicity" EXACT [] +synonym: "downregulation of natural killer cell mediated cytotoxicity" EXACT [] +synonym: "inhibition of natural killer cell mediated cytotoxicity" NARROW [] +synonym: "negative regulation of natural killer cell mediated cell death" EXACT [] +synonym: "negative regulation of natural killer cell mediated cell killing" EXACT [] +synonym: "negative regulation of natural killer cell mediated cytolysis" RELATED [] +synonym: "negative regulation of NK cell mediated cell death" EXACT [] +synonym: "negative regulation of NK cell mediated cell killing" EXACT [] +synonym: "negative regulation of NK cell mediated cytolysis" RELATED [] +synonym: "negative regulation of NK cell mediated cytotoxicity" EXACT [] +is_a: GO:0001911 ! negative regulation of leukocyte mediated cytotoxicity +is_a: GO:0002716 ! negative regulation of natural killer cell mediated immunity +is_a: GO:0042269 ! regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042267 ! natural killer cell mediated cytotoxicity +relationship: negatively_regulates GO:0042267 ! natural killer cell mediated cytotoxicity + +[Term] +id: GO:0045954 +name: positive regulation of natural killer cell mediated cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149] +synonym: "activation of natural killer cell mediated cytotoxicity" NARROW [] +synonym: "positive regulation of natural killer cell mediated cell death" EXACT [] +synonym: "positive regulation of natural killer cell mediated cell killing" EXACT [] +synonym: "positive regulation of natural killer cell mediated cytolysis" RELATED [] +synonym: "positive regulation of NK cell mediated cell death" EXACT [] +synonym: "positive regulation of NK cell mediated cell killing" EXACT [] +synonym: "positive regulation of NK cell mediated cytolysis" RELATED [] +synonym: "positive regulation of NK cell mediated cytotoxicity" EXACT [] +synonym: "stimulation of natural killer cell mediated cytotoxicity" NARROW [] +synonym: "up regulation of natural killer cell mediated cytotoxicity" EXACT [] +synonym: "up-regulation of natural killer cell mediated cytotoxicity" EXACT [] +synonym: "upregulation of natural killer cell mediated cytotoxicity" EXACT [] +is_a: GO:0001912 ! positive regulation of leukocyte mediated cytotoxicity +is_a: GO:0002717 ! positive regulation of natural killer cell mediated immunity +is_a: GO:0042269 ! regulation of natural killer cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042267 ! natural killer cell mediated cytotoxicity +relationship: positively_regulates GO:0042267 ! natural killer cell mediated cytotoxicity + +[Term] +id: GO:0045955 +name: negative regulation of calcium ion-dependent exocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis." [GOC:go_curators] +synonym: "down regulation of calcium ion-dependent exocytosis" EXACT [] +synonym: "down-regulation of calcium ion-dependent exocytosis" EXACT [] +synonym: "downregulation of calcium ion-dependent exocytosis" EXACT [] +synonym: "inhibition of calcium ion-dependent exocytosis" NARROW [] +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +is_a: GO:1903306 ! negative regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017156 ! calcium-ion regulated exocytosis +relationship: negatively_regulates GO:0017156 ! calcium-ion regulated exocytosis + +[Term] +id: GO:0045956 +name: positive regulation of calcium ion-dependent exocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis." [GOC:go_curators] +synonym: "activation of calcium ion-dependent exocytosis" NARROW [] +synonym: "stimulation of calcium ion-dependent exocytosis" NARROW [] +synonym: "up regulation of calcium ion-dependent exocytosis" EXACT [] +synonym: "up-regulation of calcium ion-dependent exocytosis" EXACT [] +synonym: "upregulation of calcium ion-dependent exocytosis" EXACT [] +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +is_a: GO:1903307 ! positive regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017156 ! calcium-ion regulated exocytosis +relationship: positively_regulates GO:0017156 ! calcium-ion regulated exocytosis + +[Term] +id: GO:0045957 +name: negative regulation of complement activation, alternative pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway." [GOC:go_curators] +synonym: "down regulation of complement activation, alternative pathway" EXACT [] +synonym: "down-regulation of complement activation, alternative pathway" EXACT [] +synonym: "downregulation of complement activation, alternative pathway" EXACT [] +synonym: "inhibition of complement activation, alternative pathway" NARROW [] +synonym: "negative regulation of complement cascade, alternative pathway" EXACT [GOC:add] +is_a: GO:0030451 ! regulation of complement activation, alternative pathway +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0045916 ! negative regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006957 ! complement activation, alternative pathway +relationship: negatively_regulates GO:0006957 ! complement activation, alternative pathway + +[Term] +id: GO:0045958 +name: positive regulation of complement activation, alternative pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway." [GOC:go_curators] +synonym: "activation of complement activation, alternative pathway" NARROW [] +synonym: "positive regulation of complement cascade, alternative pathway" EXACT [GOC:add] +synonym: "stimulation of complement activation, alternative pathway" NARROW [] +synonym: "up regulation of complement activation, alternative pathway" EXACT [] +synonym: "up-regulation of complement activation, alternative pathway" EXACT [] +synonym: "upregulation of complement activation, alternative pathway" EXACT [] +is_a: GO:0030451 ! regulation of complement activation, alternative pathway +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0045917 ! positive regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006957 ! complement activation, alternative pathway +relationship: positively_regulates GO:0006957 ! complement activation, alternative pathway + +[Term] +id: GO:0045959 +name: negative regulation of complement activation, classical pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway." [GOC:go_curators] +synonym: "down regulation of complement activation, classical pathway" EXACT [] +synonym: "down-regulation of complement activation, classical pathway" EXACT [] +synonym: "downregulation of complement activation, classical pathway" EXACT [] +synonym: "inhibition of complement activation, classical pathway" NARROW [] +synonym: "negative regulation of complement cascade, classical pathway" EXACT [GOC:add] +is_a: GO:0002924 ! negative regulation of humoral immune response mediated by circulating immunoglobulin +is_a: GO:0030450 ! regulation of complement activation, classical pathway +is_a: GO:0045916 ! negative regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006958 ! complement activation, classical pathway +relationship: negatively_regulates GO:0006958 ! complement activation, classical pathway + +[Term] +id: GO:0045960 +name: positive regulation of complement activation, classical pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway." [GOC:go_curators] +synonym: "activation of complement activation, classical pathway" NARROW [] +synonym: "positive regulation of complement cascade, classical pathway" EXACT [GOC:add] +synonym: "stimulation of complement activation, classical pathway" NARROW [] +synonym: "up regulation of complement activation, classical pathway" EXACT [] +synonym: "up-regulation of complement activation, classical pathway" EXACT [] +synonym: "upregulation of complement activation, classical pathway" EXACT [] +is_a: GO:0002925 ! positive regulation of humoral immune response mediated by circulating immunoglobulin +is_a: GO:0030450 ! regulation of complement activation, classical pathway +is_a: GO:0045917 ! positive regulation of complement activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006958 ! complement activation, classical pathway +relationship: positively_regulates GO:0006958 ! complement activation, classical pathway + +[Term] +id: GO:0045961 +name: negative regulation of development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached." [GOC:go_curators] +synonym: "down regulation of development, heterochronic" EXACT [] +synonym: "down-regulation of development, heterochronic" EXACT [] +synonym: "downregulation of development, heterochronic" EXACT [] +synonym: "inhibition of development, heterochronic" NARROW [] +is_a: GO:0040034 ! regulation of development, heterochronic + +[Term] +id: GO:0045962 +name: positive regulation of development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached." [GOC:go_curators] +synonym: "activation of development, heterochronic" NARROW [] +synonym: "stimulation of development, heterochronic" NARROW [] +synonym: "up regulation of development, heterochronic" EXACT [] +synonym: "up-regulation of development, heterochronic" EXACT [] +synonym: "upregulation of development, heterochronic" EXACT [] +is_a: GO:0040034 ! regulation of development, heterochronic + +[Term] +id: GO:0045963 +name: negative regulation of dopamine metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] +synonym: "down regulation of dopamine metabolic process" EXACT [] +synonym: "down-regulation of dopamine metabolic process" EXACT [] +synonym: "downregulation of dopamine metabolic process" EXACT [] +synonym: "inhibition of dopamine metabolic process" NARROW [] +synonym: "negative regulation of dopamine metabolism" EXACT [] +is_a: GO:0042053 ! regulation of dopamine metabolic process +is_a: GO:0045914 ! negative regulation of catecholamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042417 ! dopamine metabolic process +relationship: negatively_regulates GO:0042417 ! dopamine metabolic process + +[Term] +id: GO:0045964 +name: positive regulation of dopamine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] +synonym: "activation of dopamine metabolic process" NARROW [] +synonym: "positive regulation of dopamine metabolism" EXACT [] +synonym: "stimulation of dopamine metabolic process" NARROW [] +synonym: "up regulation of dopamine metabolic process" EXACT [] +synonym: "up-regulation of dopamine metabolic process" EXACT [] +synonym: "upregulation of dopamine metabolic process" EXACT [] +is_a: GO:0042053 ! regulation of dopamine metabolic process +is_a: GO:0045915 ! positive regulation of catecholamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042417 ! dopamine metabolic process +relationship: positively_regulates GO:0042417 ! dopamine metabolic process + +[Term] +id: GO:0045965 +name: negative regulation of ecdysteroid metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids." [GOC:go_curators] +synonym: "down regulation of ecdysteroid metabolic process" EXACT [] +synonym: "down-regulation of ecdysteroid metabolic process" EXACT [] +synonym: "downregulation of ecdysteroid metabolic process" EXACT [] +synonym: "inhibition of ecdysteroid metabolic process" NARROW [] +synonym: "negative regulation of ecdysteroid metabolism" EXACT [] +is_a: GO:0007553 ! regulation of ecdysteroid metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045939 ! negative regulation of steroid metabolic process +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045455 ! ecdysteroid metabolic process +relationship: negatively_regulates GO:0045455 ! ecdysteroid metabolic process + +[Term] +id: GO:0045966 +name: positive regulation of ecdysteroid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids." [GOC:go_curators] +synonym: "activation of ecdysteroid metabolic process" NARROW [] +synonym: "positive regulation of ecdysteroid metabolism" EXACT [] +synonym: "stimulation of ecdysteroid metabolic process" NARROW [] +synonym: "up regulation of ecdysteroid metabolic process" EXACT [] +synonym: "up-regulation of ecdysteroid metabolic process" EXACT [] +synonym: "upregulation of ecdysteroid metabolic process" EXACT [] +is_a: GO:0007553 ! regulation of ecdysteroid metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045940 ! positive regulation of steroid metabolic process +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045455 ! ecdysteroid metabolic process +relationship: positively_regulates GO:0045455 ! ecdysteroid metabolic process + +[Term] +id: GO:0045967 +name: negative regulation of growth rate +namespace: biological_process +def: "Any process that reduces the rate of growth of all or part of an organism." [GOC:mah] +comment: Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation. +synonym: "down regulation of growth rate" EXACT [] +synonym: "down-regulation of growth rate" EXACT [] +synonym: "downregulation of growth rate" EXACT [] +synonym: "inhibition of growth rate" NARROW [] +is_a: GO:0040009 ! regulation of growth rate +is_a: GO:0045926 ! negative regulation of growth + +[Term] +id: GO:0045968 +name: negative regulation of juvenile hormone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] +synonym: "down regulation of juvenile hormone biosynthetic process" EXACT [] +synonym: "down-regulation of juvenile hormone biosynthetic process" EXACT [] +synonym: "downregulation of juvenile hormone biosynthetic process" EXACT [] +synonym: "inhibition of juvenile hormone biosynthetic process" NARROW [] +synonym: "negative regulation of juvenile hormone anabolism" EXACT [] +synonym: "negative regulation of juvenile hormone biosynthesis" EXACT [] +synonym: "negative regulation of juvenile hormone formation" EXACT [] +synonym: "negative regulation of juvenile hormone synthesis" EXACT [] +is_a: GO:0007557 ! regulation of juvenile hormone biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0045928 ! negative regulation of juvenile hormone metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006718 ! juvenile hormone biosynthetic process +relationship: negatively_regulates GO:0006718 ! juvenile hormone biosynthetic process + +[Term] +id: GO:0045969 +name: positive regulation of juvenile hormone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] +synonym: "activation of juvenile hormone biosynthetic process" NARROW [] +synonym: "positive regulation of juvenile hormone anabolism" EXACT [] +synonym: "positive regulation of juvenile hormone biosynthesis" EXACT [] +synonym: "positive regulation of juvenile hormone formation" EXACT [] +synonym: "positive regulation of juvenile hormone synthesis" EXACT [] +synonym: "stimulation of juvenile hormone biosynthetic process" NARROW [] +synonym: "up regulation of juvenile hormone biosynthetic process" EXACT [] +synonym: "up-regulation of juvenile hormone biosynthetic process" EXACT [] +synonym: "upregulation of juvenile hormone biosynthetic process" EXACT [] +is_a: GO:0007557 ! regulation of juvenile hormone biosynthetic process +is_a: GO:0045929 ! positive regulation of juvenile hormone metabolic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006718 ! juvenile hormone biosynthetic process +relationship: positively_regulates GO:0006718 ! juvenile hormone biosynthetic process + +[Term] +id: GO:0045970 +name: negative regulation of juvenile hormone catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] +synonym: "down regulation of juvenile hormone catabolic process" EXACT [] +synonym: "down-regulation of juvenile hormone catabolic process" EXACT [] +synonym: "downregulation of juvenile hormone catabolic process" EXACT [] +synonym: "inhibition of juvenile hormone catabolic process" NARROW [] +synonym: "negative regulation of juvenile hormone breakdown" EXACT [] +synonym: "negative regulation of juvenile hormone catabolism" EXACT [] +synonym: "negative regulation of juvenile hormone degradation" EXACT [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045928 ! negative regulation of juvenile hormone metabolic process +is_a: GO:0045952 ! regulation of juvenile hormone catabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006719 ! juvenile hormone catabolic process +relationship: negatively_regulates GO:0006719 ! juvenile hormone catabolic process + +[Term] +id: GO:0045971 +name: positive regulation of juvenile hormone catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] +synonym: "activation of juvenile hormone catabolic process" NARROW [] +synonym: "positive regulation of juvenile hormone breakdown" EXACT [] +synonym: "positive regulation of juvenile hormone catabolism" EXACT [] +synonym: "positive regulation of juvenile hormone degradation" EXACT [] +synonym: "stimulation of juvenile hormone catabolic process" NARROW [] +synonym: "up regulation of juvenile hormone catabolic process" EXACT [] +synonym: "up-regulation of juvenile hormone catabolic process" EXACT [] +synonym: "upregulation of juvenile hormone catabolic process" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045929 ! positive regulation of juvenile hormone metabolic process +is_a: GO:0045952 ! regulation of juvenile hormone catabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006719 ! juvenile hormone catabolic process +relationship: positively_regulates GO:0006719 ! juvenile hormone catabolic process + +[Term] +id: GO:0045972 +name: negative regulation of juvenile hormone secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone." [GOC:go_curators] +synonym: "down regulation of juvenile hormone secretion" EXACT [] +synonym: "down-regulation of juvenile hormone secretion" EXACT [] +synonym: "downregulation of juvenile hormone secretion" EXACT [] +synonym: "inhibition of juvenile hormone secretion" NARROW [] +is_a: GO:0007558 ! regulation of juvenile hormone secretion +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045443 ! juvenile hormone secretion +relationship: negatively_regulates GO:0045443 ! juvenile hormone secretion + +[Term] +id: GO:0045973 +name: positive regulation of juvenile hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone." [GOC:go_curators] +synonym: "activation of juvenile hormone secretion" NARROW [] +synonym: "stimulation of juvenile hormone secretion" NARROW [] +synonym: "up regulation of juvenile hormone secretion" EXACT [] +synonym: "up-regulation of juvenile hormone secretion" EXACT [] +synonym: "upregulation of juvenile hormone secretion" EXACT [] +is_a: GO:0007558 ! regulation of juvenile hormone secretion +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045443 ! juvenile hormone secretion +relationship: positively_regulates GO:0045443 ! juvenile hormone secretion + +[Term] +id: GO:0045974 +name: regulation of translation, ncRNA-mediated +namespace: biological_process +def: "Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein." [GOC:dph, GOC:go_curators, GOC:tb] +is_a: GO:0006417 ! regulation of translation + +[Term] +id: GO:0045975 +name: positive regulation of translation, ncRNA-mediated +namespace: biological_process +def: "Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of mRNA translation, ncRNA-mediated" NARROW [] +synonym: "stimulation of mRNA translation, ncRNA-mediated" NARROW [] +synonym: "up regulation of mRNA translation, ncRNA-mediated" EXACT [] +synonym: "up-regulation of mRNA translation, ncRNA-mediated" EXACT [] +synonym: "upregulation of mRNA translation, ncRNA-mediated" EXACT [] +is_a: GO:0045727 ! positive regulation of translation +is_a: GO:0045974 ! regulation of translation, ncRNA-mediated + +[Term] +id: GO:0045976 +name: negative regulation of mitotic cell cycle, embryonic +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of progression through embryonic mitotic cell cycle" EXACT [] +synonym: "down-regulation of progression through embryonic mitotic cell cycle" EXACT [] +synonym: "downregulation of progression through embryonic mitotic cell cycle" EXACT [] +synonym: "inhibition of progression through embryonic mitotic cell cycle" NARROW [] +synonym: "negative regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of embryonic mitotic cell cycle progression" EXACT [] +synonym: "negative regulation of progression through embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009794 ! regulation of mitotic cell cycle, embryonic +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:0045992 ! negative regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045448 ! mitotic cell cycle, embryonic +relationship: negatively_regulates GO:0045448 ! mitotic cell cycle, embryonic + +[Term] +id: GO:0045977 +name: positive regulation of mitotic cell cycle, embryonic +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of mitotic cell cycle, embryonic" NARROW [] +synonym: "positive regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of embryonic mitotic cell cycle progression" EXACT [] +synonym: "positive regulation of progression through embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of mitotic cell cycle, embryonic" NARROW [] +synonym: "up regulation of mitotic cell cycle, embryonic" EXACT [] +synonym: "up-regulation of mitotic cell cycle, embryonic" EXACT [] +synonym: "upregulation of mitotic cell cycle, embryonic" EXACT [] +is_a: GO:0009794 ! regulation of mitotic cell cycle, embryonic +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045448 ! mitotic cell cycle, embryonic +relationship: positively_regulates GO:0045448 ! mitotic cell cycle, embryonic + +[Term] +id: GO:0045978 +name: negative regulation of nucleoside metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] +synonym: "down regulation of nucleoside metabolic process" EXACT [] +synonym: "down-regulation of nucleoside metabolic process" EXACT [] +synonym: "downregulation of nucleoside metabolic process" EXACT [] +synonym: "inhibition of nucleoside metabolic process" NARROW [] +synonym: "negative regulation of nucleoside metabolism" EXACT [] +is_a: GO:0009118 ! regulation of nucleoside metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009116 ! nucleoside metabolic process +relationship: negatively_regulates GO:0009116 ! nucleoside metabolic process + +[Term] +id: GO:0045979 +name: positive regulation of nucleoside metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] +synonym: "activation of nucleoside metabolic process" NARROW [] +synonym: "positive regulation of nucleoside metabolism" EXACT [] +synonym: "stimulation of nucleoside metabolic process" NARROW [] +synonym: "up regulation of nucleoside metabolic process" EXACT [] +synonym: "up-regulation of nucleoside metabolic process" EXACT [] +synonym: "upregulation of nucleoside metabolic process" EXACT [] +is_a: GO:0009118 ! regulation of nucleoside metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009116 ! nucleoside metabolic process +relationship: positively_regulates GO:0009116 ! nucleoside metabolic process + +[Term] +id: GO:0045980 +name: negative regulation of nucleotide metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] +synonym: "down regulation of nucleotide metabolic process" EXACT [] +synonym: "down-regulation of nucleotide metabolic process" EXACT [] +synonym: "downregulation of nucleotide metabolic process" EXACT [] +synonym: "inhibition of nucleotide metabolic process" NARROW [] +synonym: "negative regulation of nucleotide metabolism" EXACT [] +is_a: GO:0006140 ! regulation of nucleotide metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009117 ! nucleotide metabolic process +relationship: negatively_regulates GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0045981 +name: positive regulation of nucleotide metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] +synonym: "activation of nucleotide metabolic process" NARROW [] +synonym: "positive regulation of nucleotide metabolism" EXACT [] +synonym: "stimulation of nucleotide metabolic process" NARROW [] +synonym: "up regulation of nucleotide metabolic process" EXACT [] +synonym: "up-regulation of nucleotide metabolic process" EXACT [] +synonym: "upregulation of nucleotide metabolic process" EXACT [] +is_a: GO:0006140 ! regulation of nucleotide metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009117 ! nucleotide metabolic process +relationship: positively_regulates GO:0009117 ! nucleotide metabolic process + +[Term] +id: GO:0045982 +name: negative regulation of purine nucleobase metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases." [GOC:go_curators] +synonym: "down regulation of purine base metabolic process" EXACT [] +synonym: "down-regulation of purine base metabolic process" EXACT [] +synonym: "downregulation of purine base metabolic process" EXACT [] +synonym: "inhibition of purine base metabolic process" NARROW [] +synonym: "negative regulation of purine base metabolic process" EXACT [GOC:go_curators] +synonym: "negative regulation of purine base metabolism" EXACT [] +is_a: GO:0006141 ! regulation of purine nucleobase metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006144 ! purine nucleobase metabolic process +relationship: negatively_regulates GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0045983 +name: positive regulation of purine nucleobase metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases." [GOC:go_curators] +synonym: "activation of purine base metabolic process" NARROW [] +synonym: "positive regulation of purine base metabolic process" EXACT [] +synonym: "positive regulation of purine base metabolism" EXACT [] +synonym: "stimulation of purine base metabolic process" NARROW [] +synonym: "up regulation of purine base metabolic process" EXACT [] +synonym: "up-regulation of purine base metabolic process" EXACT [] +synonym: "upregulation of purine base metabolic process" EXACT [] +is_a: GO:0006141 ! regulation of purine nucleobase metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006144 ! purine nucleobase metabolic process +relationship: positively_regulates GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0045984 +name: negative regulation of pyrimidine nucleobase metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases." [GOC:go_curators] +synonym: "down regulation of pyrimidine base metabolic process" EXACT [] +synonym: "down-regulation of pyrimidine base metabolic process" EXACT [] +synonym: "downregulation of pyrimidine base metabolic process" EXACT [] +synonym: "inhibition of pyrimidine base metabolic process" NARROW [] +synonym: "negative regulation of pyrimidine base metabolic process" EXACT [GOC:go_curators] +synonym: "negative regulation of pyrimidine base metabolism" EXACT [] +is_a: GO:0006142 ! regulation of pyrimidine nucleobase metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006206 ! pyrimidine nucleobase metabolic process +relationship: negatively_regulates GO:0006206 ! pyrimidine nucleobase metabolic process + +[Term] +id: GO:0045985 +name: positive regulation of pyrimidine nucleobase metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases." [GOC:go_curators] +synonym: "activation of pyrimidine base metabolic process" NARROW [] +synonym: "positive regulation of pyrimidine base metabolic process" EXACT [GOC:go_curators] +synonym: "positive regulation of pyrimidine base metabolism" EXACT [] +synonym: "stimulation of pyrimidine base metabolic process" NARROW [] +synonym: "up regulation of pyrimidine base metabolic process" EXACT [] +synonym: "up-regulation of pyrimidine base metabolic process" EXACT [] +synonym: "upregulation of pyrimidine base metabolic process" EXACT [] +is_a: GO:0006142 ! regulation of pyrimidine nucleobase metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006206 ! pyrimidine nucleobase metabolic process +relationship: positively_regulates GO:0006206 ! pyrimidine nucleobase metabolic process + +[Term] +id: GO:0045986 +name: negative regulation of smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] +synonym: "down regulation of smooth muscle contraction" EXACT [] +synonym: "down-regulation of smooth muscle contraction" EXACT [] +synonym: "downregulation of smooth muscle contraction" EXACT [] +synonym: "inhibition of smooth muscle contraction" NARROW [] +synonym: "smooth muscle relaxation" RELATED [] +is_a: GO:0006940 ! regulation of smooth muscle contraction +is_a: GO:0045932 ! negative regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006939 ! smooth muscle contraction +relationship: negatively_regulates GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0045987 +name: positive regulation of smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] +synonym: "activation of smooth muscle contraction" NARROW [] +synonym: "stimulation of smooth muscle contraction" NARROW [] +synonym: "up regulation of smooth muscle contraction" EXACT [] +synonym: "up-regulation of smooth muscle contraction" EXACT [] +synonym: "upregulation of smooth muscle contraction" EXACT [] +is_a: GO:0006940 ! regulation of smooth muscle contraction +is_a: GO:0045933 ! positive regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006939 ! smooth muscle contraction +relationship: positively_regulates GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0045988 +name: negative regulation of striated muscle contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] +synonym: "down regulation of striated muscle contraction" EXACT [] +synonym: "down-regulation of striated muscle contraction" EXACT [] +synonym: "downregulation of striated muscle contraction" EXACT [] +synonym: "inhibition of striated muscle contraction" NARROW [] +is_a: GO:0006942 ! regulation of striated muscle contraction +is_a: GO:0045932 ! negative regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006941 ! striated muscle contraction +relationship: negatively_regulates GO:0006941 ! striated muscle contraction + +[Term] +id: GO:0045989 +name: positive regulation of striated muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] +synonym: "activation of striated muscle contraction" NARROW [] +synonym: "stimulation of striated muscle contraction" NARROW [] +synonym: "up regulation of striated muscle contraction" EXACT [] +synonym: "up-regulation of striated muscle contraction" EXACT [] +synonym: "upregulation of striated muscle contraction" EXACT [] +is_a: GO:0006942 ! regulation of striated muscle contraction +is_a: GO:0045933 ! positive regulation of muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006941 ! striated muscle contraction +relationship: positively_regulates GO:0006941 ! striated muscle contraction + +[Term] +id: GO:0045990 +name: carbon catabolite regulation of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources." [GOC:go_curators, GOC:mah, PMID:18359269, PMID:9618445] +synonym: "regulation of transcription by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0031670 ! cellular response to nutrient + +[Term] +id: GO:0045991 +name: carbon catabolite activation of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources." [GOC:mah, PMID:10559153] +synonym: "positive regulation of transcription by carbon catabolites" EXACT [GOC:mah] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:0045990 ! carbon catabolite regulation of transcription + +[Term] +id: GO:0045992 +name: negative regulation of embryonic development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators] +synonym: "down regulation of embryonic development" EXACT [] +synonym: "down-regulation of embryonic development" EXACT [] +synonym: "downregulation of embryonic development" EXACT [] +synonym: "inhibition of embryonic development" NARROW [] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009790 ! embryo development +relationship: negatively_regulates GO:0009790 ! embryo development + +[Term] +id: GO:0045993 +name: negative regulation of translational initiation by iron +namespace: biological_process +def: "Any process involving iron that stops, prevents or reduces the rate of translational initiation." [GOC:go_curators] +synonym: "down regulation of translational initiation by iron" EXACT [] +synonym: "down-regulation of translational initiation by iron" EXACT [] +synonym: "downregulation of translational initiation by iron" EXACT [] +synonym: "inhibition of translational initiation by iron" NARROW [] +is_a: GO:0006447 ! regulation of translational initiation by iron +is_a: GO:0045947 ! negative regulation of translational initiation + +[Term] +id: GO:0045994 +name: positive regulation of translational initiation by iron +namespace: biological_process +def: "Any process involving iron that activates or increases the rate of translational initiation." [GOC:go_curators] +synonym: "activation of translational initiation by iron" NARROW [] +synonym: "stimulation of translational initiation by iron" NARROW [] +synonym: "up regulation of translational initiation by iron" EXACT [] +synonym: "up-regulation of translational initiation by iron" EXACT [] +synonym: "upregulation of translational initiation by iron" EXACT [] +is_a: GO:0006447 ! regulation of translational initiation by iron +is_a: GO:0045948 ! positive regulation of translational initiation + +[Term] +id: GO:0045995 +name: regulation of embryonic development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009790 ! embryo development +relationship: regulates GO:0009790 ! embryo development + +[Term] +id: GO:0045996 +name: negative regulation of transcription by pheromones +namespace: biological_process +def: "Any process involving pheromones that stops, prevents or reduces the rate of transcription." [GOC:go_curators] +synonym: "down regulation of transcription by pheromones" EXACT [] +synonym: "down-regulation of transcription by pheromones" EXACT [] +synonym: "downregulation of transcription by pheromones" EXACT [] +synonym: "inhibition of transcription by pheromones" NARROW [] +is_a: GO:0009373 ! regulation of transcription by pheromones +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated + +[Term] +id: GO:0045997 +name: negative regulation of ecdysteroid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] +synonym: "down regulation of ecdysteroid biosynthetic process" EXACT [] +synonym: "down-regulation of ecdysteroid biosynthetic process" EXACT [] +synonym: "downregulation of ecdysteroid biosynthetic process" EXACT [] +synonym: "inhibition of ecdysteroid biosynthetic process" NARROW [] +synonym: "negative regulation of ecdysteroid anabolism" EXACT [] +synonym: "negative regulation of ecdysteroid biosynthesis" EXACT [] +synonym: "negative regulation of ecdysteroid formation" EXACT [] +synonym: "negative regulation of ecdysteroid synthesis" EXACT [] +is_a: GO:0007554 ! regulation of ecdysteroid biosynthetic process +is_a: GO:0045965 ! negative regulation of ecdysteroid metabolic process +is_a: GO:0090032 ! negative regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045456 ! ecdysteroid biosynthetic process +relationship: negatively_regulates GO:0045456 ! ecdysteroid biosynthetic process + +[Term] +id: GO:0045998 +name: positive regulation of ecdysteroid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] +synonym: "activation of ecdysteroid biosynthetic process" NARROW [] +synonym: "positive regulation of ecdysteroid anabolism" EXACT [] +synonym: "positive regulation of ecdysteroid biosynthesis" EXACT [] +synonym: "positive regulation of ecdysteroid formation" EXACT [] +synonym: "positive regulation of ecdysteroid synthesis" EXACT [] +synonym: "stimulation of ecdysteroid biosynthetic process" NARROW [] +synonym: "up regulation of ecdysteroid biosynthetic process" EXACT [] +synonym: "up-regulation of ecdysteroid biosynthetic process" EXACT [] +synonym: "upregulation of ecdysteroid biosynthetic process" EXACT [] +is_a: GO:0007554 ! regulation of ecdysteroid biosynthetic process +is_a: GO:0045966 ! positive regulation of ecdysteroid metabolic process +is_a: GO:0090031 ! positive regulation of steroid hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045456 ! ecdysteroid biosynthetic process +relationship: positively_regulates GO:0045456 ! ecdysteroid biosynthetic process + +[Term] +id: GO:0045999 +name: negative regulation of ecdysteroid secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid." [GOC:go_curators] +synonym: "down regulation of ecdysteroid secretion" EXACT [] +synonym: "down-regulation of ecdysteroid secretion" EXACT [] +synonym: "downregulation of ecdysteroid secretion" EXACT [] +synonym: "inhibition of ecdysteroid secretion" NARROW [] +is_a: GO:0007555 ! regulation of ecdysteroid secretion +is_a: GO:2000832 ! negative regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045457 ! ecdysteroid secretion +relationship: negatively_regulates GO:0045457 ! ecdysteroid secretion + +[Term] +id: GO:0046000 +name: positive regulation of ecdysteroid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid." [GOC:go_curators] +synonym: "activation of ecdysteroid secretion" NARROW [] +synonym: "stimulation of ecdysteroid secretion" NARROW [] +synonym: "up regulation of ecdysteroid secretion" EXACT [] +synonym: "up-regulation of ecdysteroid secretion" EXACT [] +synonym: "upregulation of ecdysteroid secretion" EXACT [] +is_a: GO:0007555 ! regulation of ecdysteroid secretion +is_a: GO:2000833 ! positive regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045457 ! ecdysteroid secretion +relationship: positively_regulates GO:0045457 ! ecdysteroid secretion + +[Term] +id: GO:0046001 +name: negative regulation of preblastoderm mitotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of progression through preblastoderm mitotic cell cycle" EXACT [] +synonym: "down-regulation of progression through preblastoderm mitotic cell cycle" EXACT [] +synonym: "downregulation of progression through preblastoderm mitotic cell cycle" EXACT [] +synonym: "inhibition of progression through preblastoderm mitotic cell cycle" NARROW [] +synonym: "negative regulation of preblastoderm mitotic cell cycle progression" EXACT [] +synonym: "negative regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007347 ! regulation of preblastoderm mitotic cell cycle +is_a: GO:0045976 ! negative regulation of mitotic cell cycle, embryonic +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035185 ! preblastoderm mitotic cell cycle +relationship: negatively_regulates GO:0035185 ! preblastoderm mitotic cell cycle + +[Term] +id: GO:0046002 +name: positive regulation of preblastoderm mitotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of progression through preblastoderm mitotic cell cycle" NARROW [] +synonym: "positive regulation of preblastoderm mitotic cell cycle progression" EXACT [] +synonym: "positive regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of progression through preblastoderm mitotic cell cycle" NARROW [] +synonym: "up regulation of progression through preblastoderm mitotic cell cycle" EXACT [] +synonym: "up-regulation of progression through preblastoderm mitotic cell cycle" EXACT [] +synonym: "upregulation of progression through preblastoderm mitotic cell cycle" EXACT [] +is_a: GO:0007347 ! regulation of preblastoderm mitotic cell cycle +is_a: GO:0045977 ! positive regulation of mitotic cell cycle, embryonic +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035185 ! preblastoderm mitotic cell cycle +relationship: positively_regulates GO:0035185 ! preblastoderm mitotic cell cycle + +[Term] +id: GO:0046003 +name: negative regulation of syncytial blastoderm mitotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "down regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +synonym: "down-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +synonym: "downregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +synonym: "inhibition of progression through syncytial blastoderm mitotic cell cycle" NARROW [] +synonym: "negative regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of syncytial blastoderm cell cycle progression" EXACT [] +is_a: GO:0007348 ! regulation of syncytial blastoderm mitotic cell cycle +is_a: GO:0045976 ! negative regulation of mitotic cell cycle, embryonic +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle +relationship: negatively_regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle + +[Term] +id: GO:0046004 +name: positive regulation of syncytial blastoderm mitotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] +synonym: "activation of progression through syncytial blastoderm mitotic cell cycle" NARROW [] +synonym: "positive regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of syncytial blastoderm cell cycle progression" EXACT [] +synonym: "stimulation of progression through syncytial blastoderm mitotic cell cycle" NARROW [] +synonym: "up regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +synonym: "up-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +synonym: "upregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] +is_a: GO:0007348 ! regulation of syncytial blastoderm mitotic cell cycle +is_a: GO:0045977 ! positive regulation of mitotic cell cycle, embryonic +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle +relationship: positively_regulates GO:0035186 ! syncytial blastoderm mitotic cell cycle + +[Term] +id: GO:0046005 +name: positive regulation of circadian sleep/wake cycle, REM sleep +namespace: biological_process +def: "Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep." [GOC:go_curators] +synonym: "activation of circadian sleep/wake cycle, REM sleep" NARROW [] +synonym: "positive regulation of REM sleep" EXACT [] +synonym: "stimulation of circadian sleep/wake cycle, REM sleep" NARROW [] +synonym: "up regulation of circadian sleep/wake cycle, REM sleep" EXACT [] +synonym: "up-regulation of circadian sleep/wake cycle, REM sleep" EXACT [] +synonym: "upregulation of circadian sleep/wake cycle, REM sleep" EXACT [] +is_a: GO:0042320 ! regulation of circadian sleep/wake cycle, REM sleep +is_a: GO:0045938 ! positive regulation of circadian sleep/wake cycle, sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep +relationship: positively_regulates GO:0042747 ! circadian sleep/wake cycle, REM sleep + +[Term] +id: GO:0046006 +name: regulation of activated T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of activated T cell proliferation." [GOC:go_curators] +synonym: "regulation of activated T lymphocyte proliferation" EXACT [] +synonym: "regulation of activated T-cell proliferation" EXACT [] +synonym: "regulation of activated T-lymphocyte proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050798 ! activated T cell proliferation +relationship: regulates GO:0050798 ! activated T cell proliferation + +[Term] +id: GO:0046007 +name: negative regulation of activated T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation." [GOC:go_curators] +synonym: "down regulation of activated T cell proliferation" EXACT [] +synonym: "down-regulation of activated T cell proliferation" EXACT [] +synonym: "downregulation of activated T cell proliferation" EXACT [] +synonym: "inhibition of activated T cell proliferation" NARROW [] +synonym: "negative regulation of activated T lymphocyte proliferation" EXACT [] +synonym: "negative regulation of activated T-cell proliferation" EXACT [] +synonym: "negative regulation of activated T-lymphocyte proliferation" EXACT [] +is_a: GO:0042130 ! negative regulation of T cell proliferation +is_a: GO:0046006 ! regulation of activated T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050798 ! activated T cell proliferation +relationship: negatively_regulates GO:0050798 ! activated T cell proliferation + +[Term] +id: GO:0046008 +name: regulation of female receptivity, post-mating +namespace: biological_process +def: "Any process that modulates the receptiveness of a female to male advances subsequent to mating." [GOC:go_curators] +is_a: GO:0045924 ! regulation of female receptivity + +[Term] +id: GO:0046009 +name: positive regulation of female receptivity, post-mating +namespace: biological_process +def: "Any process that increases the receptiveness of a female to male advances subsequent to mating." [GOC:go_curators] +synonym: "activation of female receptivity, post-mating" NARROW [] +synonym: "stimulation of female receptivity, post-mating" NARROW [] +synonym: "up regulation of female receptivity, post-mating" EXACT [] +synonym: "up-regulation of female receptivity, post-mating" EXACT [] +synonym: "upregulation of female receptivity, post-mating" EXACT [] +is_a: GO:0045925 ! positive regulation of female receptivity +is_a: GO:0046008 ! regulation of female receptivity, post-mating + +[Term] +id: GO:0046010 +name: positive regulation of circadian sleep/wake cycle, non-REM sleep +namespace: biological_process +def: "Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep." [GOC:go_curators] +synonym: "activation of circadian sleep/wake cycle, non-REM sleep" NARROW [] +synonym: "positive regulation of non-REM sleep" EXACT [] +synonym: "stimulation of circadian sleep/wake cycle, non-REM sleep" NARROW [] +synonym: "up regulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +synonym: "up-regulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +synonym: "upregulation of circadian sleep/wake cycle, non-REM sleep" EXACT [] +is_a: GO:0045188 ! regulation of circadian sleep/wake cycle, non-REM sleep +is_a: GO:0045938 ! positive regulation of circadian sleep/wake cycle, sleep +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep +relationship: positively_regulates GO:0042748 ! circadian sleep/wake cycle, non-REM sleep + +[Term] +id: GO:0046011 +name: regulation of oskar mRNA translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex." [GOC:go_curators, PMID:12538512] +is_a: GO:0006417 ! regulation of translation + +[Term] +id: GO:0046012 +name: positive regulation of oskar mRNA translation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oskar mRNA translation." [GOC:go_curators] +synonym: "activation of oskar mRNA translation" NARROW [] +synonym: "stimulation of oskar mRNA translation" NARROW [] +synonym: "up regulation of oskar mRNA translation" EXACT [] +synonym: "up-regulation of oskar mRNA translation" EXACT [] +synonym: "upregulation of oskar mRNA translation" EXACT [] +is_a: GO:0045727 ! positive regulation of translation +is_a: GO:0046011 ! regulation of oskar mRNA translation + +[Term] +id: GO:0046013 +name: regulation of T cell homeostatic proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] +synonym: "regulation of resting T cell proliferation" EXACT [] +synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] +synonym: "regulation of T-cell homeostatic proliferation" EXACT [] +synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001777 ! T cell homeostatic proliferation +relationship: regulates GO:0001777 ! T cell homeostatic proliferation + +[Term] +id: GO:0046014 +name: negative regulation of T cell homeostatic proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] +synonym: "down regulation of T cell homeostatic proliferation" EXACT [] +synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] +synonym: "downregulation of T cell homeostatic proliferation" EXACT [] +synonym: "inhibition of T cell homeostatic proliferation" NARROW [] +synonym: "negative regulation of resting T cell proliferation" EXACT [] +synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] +synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] +synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] +is_a: GO:0042130 ! negative regulation of T cell proliferation +is_a: GO:0046013 ! regulation of T cell homeostatic proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001777 ! T cell homeostatic proliferation +relationship: negatively_regulates GO:0001777 ! T cell homeostatic proliferation + +[Term] +id: GO:0046015 +name: regulation of transcription by glucose +namespace: biological_process +def: "Any process involving glucose that modulates the frequency, rate or extent or transcription." [GOC:go_curators] +is_a: GO:0006355 ! regulation of transcription, DNA-templated + +[Term] +id: GO:0046016 +name: positive regulation of transcription by glucose +namespace: biological_process +def: "Any process involving glucose that activates or increases the rate of transcription." [GOC:go_curators] +synonym: "activation of transcription by glucose" NARROW [] +synonym: "stimulation of transcription by glucose" NARROW [] +synonym: "up regulation of transcription by glucose" EXACT [] +synonym: "up-regulation of transcription by glucose" EXACT [] +synonym: "upregulation of transcription by glucose" EXACT [] +is_a: GO:0045991 ! carbon catabolite activation of transcription +is_a: GO:0046015 ! regulation of transcription by glucose + +[Term] +id: GO:0046017 +name: obsolete regulation of transcription from RNA polymerase I promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "mitotic regulation of transcription from Pol I promoter" EXACT [] +synonym: "regulation of transcription from Pol I promoter during mitosis" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046018 +name: obsolete positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "activation of transcription from RNA polymerase I promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic activation of transcription from Pol I promoter" EXACT [] +synonym: "positive regulation of transcription from Pol I promoter during mitosis" EXACT [GOC:mah] +synonym: "positive regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [GOC:mah] +synonym: "stimulation of transcription from RNA polymerase I promoter during mitosis" NARROW [GOC:mah] +synonym: "up regulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +synonym: "up-regulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +synonym: "upregulation of transcription from RNA polymerase I promoter during mitosis" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046019 +name: regulation of transcription from RNA polymerase II promoter by pheromones +namespace: biological_process +def: "Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] +synonym: "regulation of transcription from Pol II promoter by pheromones" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0009373 ! regulation of transcription by pheromones + +[Term] +id: GO:0046020 +name: negative regulation of transcription from RNA polymerase II promoter by pheromones +namespace: biological_process +def: "Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:go_curators] +synonym: "down regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +synonym: "downregulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] +synonym: "inhibition of transcription from RNA polymerase II promoter by pheromones" NARROW [] +synonym: "negative regulation of transcription from Pol II promoter by pheromones" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0045996 ! negative regulation of transcription by pheromones +is_a: GO:0046019 ! regulation of transcription from RNA polymerase II promoter by pheromones + +[Term] +id: GO:0046021 +name: obsolete regulation of transcription from RNA polymerase II promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "mitotic regulation of transcription from Pol II promoter" EXACT [] +synonym: "regulation of transcription from Pol II promoter, mitotic" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046022 +name: obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "activation of transcription from RNA polymerase II promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic activation of transcription from Pol II promoter" EXACT [] +synonym: "positive regulation of transcription from Pol II promoter during mitosis" EXACT [GOC:mah] +synonym: "positive regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [GOC:mah] +synonym: "stimulation of transcription from RNA polymerase II promoter during mitosis" NARROW [GOC:mah] +synonym: "up regulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +synonym: "up-regulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +synonym: "upregulation of transcription from RNA polymerase II promoter during mitosis" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046023 +name: obsolete regulation of transcription from RNA polymerase III promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "mitotic regulation of transcription from Pol III promoter" EXACT [] +synonym: "regulation of transcription from Pol III promoter, mitotic" EXACT [] +synonym: "regulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046024 +name: obsolete positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle." [GOC:go_curators] +comment: The reason for obsoletion is that 'during' should be captured using an annotation extension. +synonym: "activation of transcription from RNA polymerase III promoter during mitosis" NARROW [GOC:mah] +synonym: "mitotic activation of transcription from Pol III promoter" EXACT [] +synonym: "positive regulation of transcription from Pol III promoter during mitosis" EXACT [GOC:mah] +synonym: "positive regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [GOC:mah] +synonym: "stimulation of transcription from RNA polymerase III promoter during mitosis" NARROW [GOC:mah] +synonym: "up regulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +synonym: "up-regulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +synonym: "upregulation of transcription from RNA polymerase III promoter during mitosis" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14896 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0046025 +name: precorrin-6Y C5,15-methyltransferase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2." [EC:2.1.1.132] +synonym: "precorrin-6 methyltransferase activity" BROAD [EC:2.1.1.132] +synonym: "precorrin-6Y methylase activity" BROAD [EC:2.1.1.132] +synonym: "S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)" EXACT [EC:2.1.1.132] +xref: EC:2.1.1.132 +xref: MetaCyc:2.1.1.132-RXN +xref: RHEA:17477 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0046026 +name: precorrin-4 C11-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5." [EC:2.1.1.133] +synonym: "CobM" RELATED [EC:2.1.1.133] +synonym: "S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity" EXACT [EC:2.1.1.133] +xref: EC:2.1.1.133 +xref: MetaCyc:2.1.1.133-RXN +xref: RHEA:22012 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0046027 +name: phospholipid:diacylglycerol acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol." [EC:2.3.1.158] +synonym: "PDAT activity" EXACT [EC:2.3.1.158] +synonym: "phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity" EXACT [EC:2.3.1.158] +xref: EC:2.3.1.158 +xref: MetaCyc:2.3.1.158-RXN +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0046028 +name: electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity +namespace: molecular_function +def: "Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II." [GOC:ai, ISBN:0716731363] +synonym: "plastocyanin" NARROW [] +is_a: GO:0009055 ! electron transfer activity + +[Term] +id: GO:0046029 +name: mannitol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH." [EC:1.1.1.255, RHEA:15029] +synonym: "mannitol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.255] +synonym: "MTD activity" EXACT [EC:1.1.1.255] +synonym: "NAD-dependent mannitol dehydrogenase activity" BROAD [EC:1.1.1.255] +xref: EC:1.1.1.255 +xref: KEGG_REACTION:R07135 +xref: MetaCyc:1.1.1.255-RXN +xref: RHEA:15029 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +is_a: GO:0031320 ! hexitol dehydrogenase activity + +[Term] +id: GO:0046030 +name: inositol trisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate." [GOC:bf] +synonym: "inositol-1,4,5-trisphosphate phosphatase" NARROW [] +synonym: "IP(3) phosphatase activity" EXACT [] +synonym: "IP3 phosphatase activity" EXACT [] +is_a: GO:0052745 ! inositol phosphate phosphatase activity + +[Term] +id: GO:0046031 +name: ADP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate." [GOC:go_curators] +synonym: "ADP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009179 ! purine ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0046032 +name: ADP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate." [GOC:go_curators] +synonym: "ADP breakdown" EXACT [] +synonym: "ADP catabolism" EXACT [] +synonym: "ADP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009181 ! purine ribonucleoside diphosphate catabolic process +is_a: GO:0046031 ! ADP metabolic process + +[Term] +id: GO:0046033 +name: AMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving AMP, adenosine monophosphate." [GOC:go_curators] +synonym: "adenylate forming enzyme activity" RELATED [] +synonym: "AMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0046034 +name: ATP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator." [GOC:go_curators] +synonym: "ATP metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0046035 +name: CMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving CMP, cytidine monophosphate." [GOC:go_curators] +synonym: "CMP metabolism" EXACT [] +is_a: GO:0009173 ! pyrimidine ribonucleoside monophosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046036 +name: CTP metabolic process +namespace: biological_process +alt_id: GO:0006243 +def: "The chemical reactions and pathways involving CTP, cytidine triphosphate." [GOC:go_curators] +synonym: "CTP deamination" NARROW [] +synonym: "CTP metabolism" EXACT [] +is_a: GO:0009208 ! pyrimidine ribonucleoside triphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046037 +name: GMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GMP, guanosine monophosphate." [GOC:go_curators] +synonym: "GMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0046038 +name: GMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate." [GOC:go_curators] +synonym: "GMP breakdown" EXACT [] +synonym: "GMP catabolism" EXACT [] +synonym: "GMP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009169 ! purine ribonucleoside monophosphate catabolic process +is_a: GO:0046037 ! GMP metabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0046039 +name: GTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GTP, guanosine triphosphate." [GOC:go_curators] +synonym: "GTP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009205 ! purine ribonucleoside triphosphate metabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0046040 +name: IMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving IMP, inosine monophosphate." [GOC:go_curators] +synonym: "IMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process + +[Term] +id: GO:0046041 +name: ITP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ITP, inosine triphosphate." [GOC:go_curators] +synonym: "ITP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009205 ! purine ribonucleoside triphosphate metabolic process + +[Term] +id: GO:0046042 +name: ITP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate." [GOC:go_curators] +synonym: "ITP anabolism" EXACT [] +synonym: "ITP biosynthesis" EXACT [] +synonym: "ITP formation" EXACT [] +synonym: "ITP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009206 ! purine ribonucleoside triphosphate biosynthetic process +is_a: GO:0046041 ! ITP metabolic process + +[Term] +id: GO:0046043 +name: TDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving TDP, ribosylthymine diphosphate." [GOC:go_curators] +synonym: "TDP metabolism" EXACT [] +is_a: GO:0009193 ! pyrimidine ribonucleoside diphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046044 +name: TMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving TMP, ribosylthymine monophosphate." [GOC:go_curators] +synonym: "TMP metabolism" EXACT [] +is_a: GO:0009173 ! pyrimidine ribonucleoside monophosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046045 +name: TMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate." [GOC:go_curators] +synonym: "TMP breakdown" EXACT [] +synonym: "TMP catabolism" EXACT [] +synonym: "TMP degradation" EXACT [] +is_a: GO:0009175 ! pyrimidine ribonucleoside monophosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046044 ! TMP metabolic process + +[Term] +id: GO:0046046 +name: TTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving TTP, ribosylthymine triphosphate." [GOC:go_curators] +synonym: "TTP metabolism" EXACT [] +is_a: GO:0009208 ! pyrimidine ribonucleoside triphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046047 +name: TTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate." [GOC:go_curators] +synonym: "TTP breakdown" EXACT [] +synonym: "TTP catabolism" EXACT [] +synonym: "TTP degradation" EXACT [] +synonym: "TTP hydrolysis" EXACT [] +is_a: GO:0009210 ! pyrimidine ribonucleoside triphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046046 ! TTP metabolic process + +[Term] +id: GO:0046048 +name: UDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate." [GOC:go_curators] +synonym: "UDP metabolism" EXACT [] +is_a: GO:0009193 ! pyrimidine ribonucleoside diphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046049 +name: UMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UMP, uridine monophosphate." [GOC:go_curators] +synonym: "UMP metabolism" EXACT [] +is_a: GO:0009173 ! pyrimidine ribonucleoside monophosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046050 +name: UMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate." [GOC:go_curators] +synonym: "UMP breakdown" EXACT [] +synonym: "UMP catabolism" EXACT [] +synonym: "UMP degradation" EXACT [] +is_a: GO:0009175 ! pyrimidine ribonucleoside monophosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046049 ! UMP metabolic process + +[Term] +id: GO:0046051 +name: UTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate." [GOC:go_curators] +synonym: "UTP metabolism" EXACT [] +is_a: GO:0009208 ! pyrimidine ribonucleoside triphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046052 +name: UTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate." [GOC:go_curators] +synonym: "UTP breakdown" EXACT [] +synonym: "UTP catabolism" EXACT [] +synonym: "UTP degradation" EXACT [] +synonym: "UTP hydrolysis" EXACT [] +is_a: GO:0009210 ! pyrimidine ribonucleoside triphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046051 ! UTP metabolic process + +[Term] +id: GO:0046053 +name: dAMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)." [GOC:go_curators] +synonym: "dAMP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009170 ! purine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0046054 +name: dGMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)." [GOC:go_curators] +synonym: "dGMP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009170 ! purine deoxyribonucleoside monophosphate metabolic process + +[Term] +id: GO:0046055 +name: dGMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)." [GOC:go_curators] +synonym: "dGMP breakdown" EXACT [] +synonym: "dGMP catabolism" EXACT [] +synonym: "dGMP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009172 ! purine deoxyribonucleoside monophosphate catabolic process +is_a: GO:0046054 ! dGMP metabolic process + +[Term] +id: GO:0046056 +name: dADP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)." [GOC:go_curators] +synonym: "dADP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009182 ! purine deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0046057 +name: dADP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)." [GOC:go_curators] +synonym: "dADP breakdown" EXACT [] +synonym: "dADP catabolism" EXACT [] +synonym: "dADP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009184 ! purine deoxyribonucleoside diphosphate catabolic process +is_a: GO:0046056 ! dADP metabolic process + +[Term] +id: GO:0046058 +name: cAMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:go_curators] +synonym: "3',5' cAMP metabolic process" EXACT [] +synonym: "3',5' cAMP metabolism" EXACT [] +synonym: "3',5'-cAMP metabolic process" EXACT [] +synonym: "3',5'-cAMP metabolism" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate metabolic process" EXACT [] +synonym: "adenosine 3',5'-cyclophosphate metabolism" EXACT [] +synonym: "cAMP generating peptide activity" RELATED [] +synonym: "cAMP metabolism" EXACT [] +synonym: "cyclic AMP metabolic process" EXACT [] +synonym: "cyclic AMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009187 ! cyclic nucleotide metabolic process + +[Term] +id: GO:0046059 +name: dAMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)." [GOC:go_curators] +synonym: "dAMP breakdown" EXACT [] +synonym: "dAMP catabolism" EXACT [] +synonym: "dAMP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009172 ! purine deoxyribonucleoside monophosphate catabolic process +is_a: GO:0046053 ! dAMP metabolic process + +[Term] +id: GO:0046060 +name: dATP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)." [GOC:go_curators] +synonym: "dATP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009215 ! purine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0046061 +name: dATP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)." [GOC:go_curators] +synonym: "dATP breakdown" EXACT [] +synonym: "dATP catabolism" EXACT [] +synonym: "dATP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009217 ! purine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0046060 ! dATP metabolic process + +[Term] +id: GO:0046062 +name: dCDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate." [GOC:go_curators] +synonym: "dCDP metabolism" EXACT [] +is_a: GO:0009196 ! pyrimidine deoxyribonucleoside diphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046063 +name: dCMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate." [GOC:go_curators] +synonym: "dCMP metabolism" EXACT [] +is_a: GO:0009176 ! pyrimidine deoxyribonucleoside monophosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046064 +name: dCMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate." [GOC:go_curators] +synonym: "dCMP anabolism" EXACT [] +synonym: "dCMP biosynthesis" EXACT [] +synonym: "dCMP formation" EXACT [] +synonym: "dCMP synthesis" EXACT [] +is_a: GO:0009177 ! pyrimidine deoxyribonucleoside monophosphate biosynthetic process +is_a: GO:0009221 ! pyrimidine deoxyribonucleotide biosynthetic process +is_a: GO:0046063 ! dCMP metabolic process + +[Term] +id: GO:0046065 +name: dCTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate." [GOC:go_curators] +synonym: "dCTP metabolism" EXACT [] +is_a: GO:0009211 ! pyrimidine deoxyribonucleoside triphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046066 +name: dGDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)." [GOC:go_curators] +synonym: "dGDP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009182 ! purine deoxyribonucleoside diphosphate metabolic process + +[Term] +id: GO:0046067 +name: dGDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)." [GOC:go_curators] +synonym: "dGDP breakdown" EXACT [] +synonym: "dGDP catabolism" EXACT [] +synonym: "dGDP degradation" EXACT [] +is_a: GO:0009155 ! purine deoxyribonucleotide catabolic process +is_a: GO:0009184 ! purine deoxyribonucleoside diphosphate catabolic process +is_a: GO:0046066 ! dGDP metabolic process + +[Term] +id: GO:0046068 +name: cGMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate." [GOC:go_curators] +synonym: "cGMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009187 ! cyclic nucleotide metabolic process + +[Term] +id: GO:0046069 +name: cGMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate." [GOC:go_curators] +synonym: "cGMP breakdown" EXACT [] +synonym: "cGMP catabolism" EXACT [] +synonym: "cGMP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009214 ! cyclic nucleotide catabolic process +is_a: GO:0046068 ! cGMP metabolic process + +[Term] +id: GO:0046070 +name: dGTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dGTP, guanosine triphosphate." [GOC:go_curators] +synonym: "dGTP metabolism" EXACT [] +is_a: GO:0009151 ! purine deoxyribonucleotide metabolic process +is_a: GO:0009215 ! purine deoxyribonucleoside triphosphate metabolic process + +[Term] +id: GO:0046071 +name: dGTP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate." [GOC:go_curators] +synonym: "dGTP anabolism" EXACT [] +synonym: "dGTP biosynthesis" EXACT [] +synonym: "dGTP formation" EXACT [] +synonym: "dGTP synthesis" EXACT [] +is_a: GO:0009153 ! purine deoxyribonucleotide biosynthetic process +is_a: GO:0009216 ! purine deoxyribonucleoside triphosphate biosynthetic process +is_a: GO:0046070 ! dGTP metabolic process + +[Term] +id: GO:0046072 +name: dTDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate." [GOC:go_curators] +synonym: "dTDP metabolism" EXACT [] +is_a: GO:0009196 ! pyrimidine deoxyribonucleoside diphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046073 +name: dTMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)." [GOC:go_curators] +synonym: "dTMP metabolism" EXACT [] +is_a: GO:0009176 ! pyrimidine deoxyribonucleoside monophosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046074 +name: dTMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate." [GOC:go_curators] +synonym: "dTMP breakdown" EXACT [] +synonym: "dTMP catabolism" EXACT [] +synonym: "dTMP degradation" EXACT [] +is_a: GO:0009178 ! pyrimidine deoxyribonucleoside monophosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046073 ! dTMP metabolic process + +[Term] +id: GO:0046075 +name: dTTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate." [GOC:go_curators] +synonym: "dTTP metabolism" EXACT [] +is_a: GO:0009211 ! pyrimidine deoxyribonucleoside triphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046076 +name: dTTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate." [GOC:go_curators] +synonym: "dTTP breakdown" EXACT [] +synonym: "dTTP catabolism" EXACT [] +synonym: "dTTP degradation" EXACT [] +is_a: GO:0009213 ! pyrimidine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046075 ! dTTP metabolic process + +[Term] +id: GO:0046077 +name: dUDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate." [GOC:go_curators] +synonym: "dUDP metabolism" EXACT [] +is_a: GO:0009196 ! pyrimidine deoxyribonucleoside diphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046078 +name: dUMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate)." [GOC:go_curators] +synonym: "dUMP metabolism" EXACT [] +is_a: GO:0009176 ! pyrimidine deoxyribonucleoside monophosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046079 +name: dUMP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate." [GOC:go_curators] +synonym: "dUMP breakdown" EXACT [] +synonym: "dUMP catabolism" EXACT [] +synonym: "dUMP degradation" EXACT [] +is_a: GO:0009178 ! pyrimidine deoxyribonucleoside monophosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046078 ! dUMP metabolic process + +[Term] +id: GO:0046080 +name: dUTP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate." [GOC:go_curators] +synonym: "dUTP metabolism" EXACT [] +is_a: GO:0009211 ! pyrimidine deoxyribonucleoside triphosphate metabolic process +is_a: GO:0009219 ! pyrimidine deoxyribonucleotide metabolic process + +[Term] +id: GO:0046081 +name: dUTP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate." [GOC:go_curators] +synonym: "dUTP breakdown" EXACT [] +synonym: "dUTP catabolism" EXACT [] +synonym: "dUTP degradation" EXACT [] +is_a: GO:0009213 ! pyrimidine deoxyribonucleoside triphosphate catabolic process +is_a: GO:0009223 ! pyrimidine deoxyribonucleotide catabolic process +is_a: GO:0046080 ! dUTP metabolic process + +[Term] +id: GO:0046082 +name: 5-methylcytosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA." [GOC:go_curators] +synonym: "5-methylcytosine anabolism" EXACT [] +synonym: "5-methylcytosine biosynthesis" EXACT [] +synonym: "5-methylcytosine formation" EXACT [] +synonym: "5-methylcytosine synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0019857 ! 5-methylcytosine metabolic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process + +[Term] +id: GO:0046083 +name: adenine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine." [GOC:go_curators] +synonym: "adenine metabolism" EXACT [] +is_a: GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0046084 +name: adenine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine." [GOC:go_curators] +synonym: "adenine anabolism" EXACT [] +synonym: "adenine biosynthesis" EXACT [] +synonym: "adenine formation" EXACT [] +synonym: "adenine synthesis" EXACT [] +is_a: GO:0009113 ! purine nucleobase biosynthetic process +is_a: GO:0046083 ! adenine metabolic process + +[Term] +id: GO:0046085 +name: adenosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes." [GOC:go_curators] +synonym: "adenosine metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0046086 +name: adenosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes." [GOC:go_curators] +synonym: "adenosine anabolism" EXACT [] +synonym: "adenosine biosynthesis" EXACT [] +synonym: "adenosine formation" EXACT [] +synonym: "adenosine synthesis" EXACT [] +is_a: GO:0046085 ! adenosine metabolic process +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process + +[Term] +id: GO:0046087 +name: cytidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside." [GOC:go_curators] +synonym: "cytidine metabolism" EXACT [] +is_a: GO:0046131 ! pyrimidine ribonucleoside metabolic process + +[Term] +id: GO:0046088 +name: cytidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside." [GOC:go_curators] +synonym: "cytidine anabolism" EXACT [] +synonym: "cytidine biosynthesis" EXACT [] +synonym: "cytidine formation" EXACT [] +synonym: "cytidine synthesis" EXACT [] +is_a: GO:0046087 ! cytidine metabolic process +is_a: GO:0046132 ! pyrimidine ribonucleoside biosynthetic process + +[Term] +id: GO:0046089 +name: cytosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives." [GOC:go_curators] +synonym: "cytosine anabolism" EXACT [] +synonym: "cytosine biosynthesis" EXACT [] +synonym: "cytosine formation" EXACT [] +synonym: "cytosine synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0019856 ! pyrimidine nucleobase biosynthetic process +is_a: GO:0019858 ! cytosine metabolic process + +[Term] +id: GO:0046090 +name: deoxyadenosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyadenosine metabolism" EXACT [] +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046091 +name: deoxyadenosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyadenosine anabolism" EXACT [] +synonym: "deoxyadenosine biosynthesis" EXACT [] +synonym: "deoxyadenosine formation" EXACT [] +synonym: "deoxyadenosine synthesis" EXACT [] +is_a: GO:0046090 ! deoxyadenosine metabolic process +is_a: GO:0046123 ! purine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0046092 +name: deoxycytidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxycytidine metabolism" EXACT [] +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046093 +name: deoxycytidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxycytidine anabolism" EXACT [] +synonym: "deoxycytidine biosynthesis" EXACT [] +synonym: "deoxycytidine formation" EXACT [] +synonym: "deoxycytidine synthesis" EXACT [] +is_a: GO:0046092 ! deoxycytidine metabolic process +is_a: GO:0046126 ! pyrimidine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0046094 +name: deoxyinosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside." [GOC:go_curators] +synonym: "deoxyinosine metabolism" EXACT [] +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046095 +name: deoxyinosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside." [GOC:go_curators] +synonym: "deoxyinosine anabolism" EXACT [] +synonym: "deoxyinosine biosynthesis" EXACT [] +synonym: "deoxyinosine formation" EXACT [] +synonym: "deoxyinosine synthesis" EXACT [] +is_a: GO:0046094 ! deoxyinosine metabolic process +is_a: GO:0046123 ! purine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0046096 +name: deoxyuridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyuridine metabolism" EXACT [] +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046097 +name: deoxyuridine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA." [GOC:go_curators] +synonym: "deoxyuridine anabolism" EXACT [] +synonym: "deoxyuridine biosynthesis" EXACT [] +synonym: "deoxyuridine formation" EXACT [] +synonym: "deoxyuridine synthesis" EXACT [] +is_a: GO:0046096 ! deoxyuridine metabolic process +is_a: GO:0046126 ! pyrimidine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0046098 +name: guanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important." [GOC:go_curators] +synonym: "guanine metabolism" EXACT [] +is_a: GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0046099 +name: guanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important." [GOC:go_curators] +synonym: "guanine anabolism" EXACT [] +synonym: "guanine biosynthesis" EXACT [] +synonym: "guanine formation" EXACT [] +synonym: "guanine synthesis" EXACT [] +is_a: GO:0009113 ! purine nucleobase biosynthetic process +is_a: GO:0046098 ! guanine metabolic process + +[Term] +id: GO:0046100 +name: hypoxanthine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate." [GOC:go_curators] +synonym: "hypoxanthine metabolism" EXACT [] +is_a: GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0046101 +name: hypoxanthine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate." [GOC:go_curators] +synonym: "hypoxanthine anabolism" EXACT [] +synonym: "hypoxanthine biosynthesis" EXACT [] +synonym: "hypoxanthine formation" EXACT [] +synonym: "hypoxanthine synthesis" EXACT [] +is_a: GO:0009113 ! purine nucleobase biosynthetic process +is_a: GO:0046100 ! hypoxanthine metabolic process + +[Term] +id: GO:0046102 +name: inosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs." [GOC:go_curators] +synonym: "inosine metabolism" EXACT [] +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0046103 +name: inosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs." [GOC:go_curators] +synonym: "inosine anabolism" EXACT [] +synonym: "inosine biosynthesis" EXACT [] +synonym: "inosine formation" EXACT [] +synonym: "inosine synthesis" EXACT [] +is_a: GO:0046102 ! inosine metabolic process +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process + +[Term] +id: GO:0046104 +name: thymidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA." [GOC:go_curators] +synonym: "deoxyribosylthymine metabolic process" EXACT [] +synonym: "deoxyribosylthymine metabolism" EXACT [] +synonym: "thymidine metabolism" EXACT [] +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046105 +name: thymidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA." [GOC:go_curators] +synonym: "deoxyribosylthymine biosynthesis" EXACT [] +synonym: "deoxyribosylthymine biosynthetic process" EXACT [] +synonym: "thymidine anabolism" EXACT [] +synonym: "thymidine biosynthesis" EXACT [] +synonym: "thymidine formation" EXACT [] +synonym: "thymidine synthesis" EXACT [] +is_a: GO:0046104 ! thymidine metabolic process +is_a: GO:0046126 ! pyrimidine deoxyribonucleoside biosynthetic process + +[Term] +id: GO:0046106 +name: thymine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base." [GOC:go_curators] +synonym: "thymine anabolism" EXACT [] +synonym: "thymine biosynthesis" EXACT [] +synonym: "thymine formation" EXACT [] +synonym: "thymine synthesis" EXACT [] +is_a: GO:0019856 ! pyrimidine nucleobase biosynthetic process +is_a: GO:0019859 ! thymine metabolic process + +[Term] +id: GO:0046107 +name: uracil biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA." [GOC:go_curators] +synonym: "uracil anabolism" EXACT [] +synonym: "uracil biosynthesis" EXACT [] +synonym: "uracil formation" EXACT [] +synonym: "uracil synthesis" EXACT [] +is_a: GO:0019856 ! pyrimidine nucleobase biosynthetic process +is_a: GO:0019860 ! uracil metabolic process + +[Term] +id: GO:0046108 +name: uridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids." [GOC:go_curators] +synonym: "uridine metabolism" EXACT [] +is_a: GO:0046131 ! pyrimidine ribonucleoside metabolic process + +[Term] +id: GO:0046109 +name: uridine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids." [GOC:go_curators] +synonym: "uridine anabolism" EXACT [] +synonym: "uridine biosynthesis" EXACT [] +synonym: "uridine formation" EXACT [] +synonym: "uridine synthesis" EXACT [] +is_a: GO:0046108 ! uridine metabolic process +is_a: GO:0046132 ! pyrimidine ribonucleoside biosynthetic process + +[Term] +id: GO:0046110 +name: xanthine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids." [GOC:go_curators] +synonym: "xanthine metabolism" EXACT [] +is_a: GO:0006144 ! purine nucleobase metabolic process + +[Term] +id: GO:0046111 +name: xanthine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids." [GOC:go_curators] +synonym: "xanthine anabolism" EXACT [] +synonym: "xanthine biosynthesis" EXACT [] +synonym: "xanthine formation" EXACT [] +synonym: "xanthine synthesis" EXACT [] +is_a: GO:0009113 ! purine nucleobase biosynthetic process +is_a: GO:0046110 ! xanthine metabolic process + +[Term] +id: GO:0046112 +name: nucleobase biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] +synonym: "nucleobase anabolism" EXACT [] +synonym: "nucleobase biosynthesis" EXACT [] +synonym: "nucleobase formation" EXACT [] +synonym: "nucleobase synthesis" EXACT [] +is_a: GO:0009112 ! nucleobase metabolic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0046113 +name: nucleobase catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] +synonym: "nucleobase breakdown" EXACT [] +synonym: "nucleobase catabolism" EXACT [] +synonym: "nucleobase degradation" EXACT [] +is_a: GO:0009112 ! nucleobase metabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0046114 +name: guanosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution." [GOC:go_curators] +synonym: "guanosine anabolism" EXACT [] +synonym: "guanosine biosynthesis" EXACT [] +synonym: "guanosine formation" EXACT [] +synonym: "guanosine synthesis" EXACT [] +is_a: GO:0008617 ! guanosine metabolic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0046115 +name: guanosine catabolic process +namespace: biological_process +alt_id: GO:0006160 +def: "The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution." [GOC:go_curators] +synonym: "guanosine breakdown" EXACT [] +synonym: "guanosine catabolism" EXACT [] +synonym: "guanosine degradation" EXACT [] +synonym: "guanosine phosphorolysis" RELATED [] +is_a: GO:0008617 ! guanosine metabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0046116 +name: queuosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents." [ISBN:0198506732] +synonym: "queuosine metabolism" EXACT [] +is_a: GO:0009119 ! ribonucleoside metabolic process + +[Term] +id: GO:0046117 +name: queuosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents." [ISBN:0198506732] +synonym: "queuosine breakdown" EXACT [] +synonym: "queuosine catabolism" EXACT [] +synonym: "queuosine degradation" EXACT [] +is_a: GO:0042454 ! ribonucleoside catabolic process +is_a: GO:0046116 ! queuosine metabolic process + +[Term] +id: GO:0046118 +name: 7-methylguanosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA." [ISBN:0198506732] +synonym: "7-methylguanosine anabolism" EXACT [] +synonym: "7-methylguanosine biosynthesis" EXACT [] +synonym: "7-methylguanosine formation" EXACT [] +synonym: "7-methylguanosine synthesis" EXACT [] +is_a: GO:0008618 ! 7-methylguanosine metabolic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0046119 +name: 7-methylguanosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA." [ISBN:0198506732] +synonym: "7-methylguanosine breakdown" EXACT [] +synonym: "7-methylguanosine catabolism" EXACT [] +synonym: "7-methylguanosine degradation" EXACT [] +is_a: GO:0008618 ! 7-methylguanosine metabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0046120 +name: deoxyribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "deoxyribonucleoside anabolism" EXACT [] +synonym: "deoxyribonucleoside biosynthesis" EXACT [] +synonym: "deoxyribonucleoside formation" EXACT [] +synonym: "deoxyribonucleoside synthesis" EXACT [] +is_a: GO:0009120 ! deoxyribonucleoside metabolic process +is_a: GO:0009163 ! nucleoside biosynthetic process + +[Term] +id: GO:0046121 +name: deoxyribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "deoxyribonucleoside breakdown" EXACT [] +synonym: "deoxyribonucleoside catabolism" EXACT [] +synonym: "deoxyribonucleoside degradation" EXACT [] +is_a: GO:0009120 ! deoxyribonucleoside metabolic process +is_a: GO:0009164 ! nucleoside catabolic process + +[Term] +id: GO:0046122 +name: purine deoxyribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "purine deoxyribonucleoside metabolism" EXACT [] +is_a: GO:0009120 ! deoxyribonucleoside metabolic process +is_a: GO:0042278 ! purine nucleoside metabolic process + +[Term] +id: GO:0046123 +name: purine deoxyribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "purine deoxyribonucleoside anabolism" EXACT [] +synonym: "purine deoxyribonucleoside biosynthesis" EXACT [] +synonym: "purine deoxyribonucleoside formation" EXACT [] +synonym: "purine deoxyribonucleoside synthesis" EXACT [] +is_a: GO:0042451 ! purine nucleoside biosynthetic process +is_a: GO:0046120 ! deoxyribonucleoside biosynthetic process +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046124 +name: purine deoxyribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "purine deoxyribonucleoside breakdown" EXACT [] +synonym: "purine deoxyribonucleoside catabolism" EXACT [] +synonym: "purine deoxyribonucleoside degradation" EXACT [] +is_a: GO:0006152 ! purine nucleoside catabolic process +is_a: GO:0046121 ! deoxyribonucleoside catabolic process +is_a: GO:0046122 ! purine deoxyribonucleoside metabolic process + +[Term] +id: GO:0046125 +name: pyrimidine deoxyribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "pyrimidine deoxyribonucleoside metabolism" EXACT [] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0009120 ! deoxyribonucleoside metabolic process + +[Term] +id: GO:0046126 +name: pyrimidine deoxyribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "pyrimidine deoxyribonucleoside anabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside biosynthesis" EXACT [] +synonym: "pyrimidine deoxyribonucleoside formation" EXACT [] +synonym: "pyrimidine deoxyribonucleoside synthesis" EXACT [] +is_a: GO:0046120 ! deoxyribonucleoside biosynthetic process +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process +is_a: GO:0046134 ! pyrimidine nucleoside biosynthetic process + +[Term] +id: GO:0046127 +name: pyrimidine deoxyribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "pyrimidine deoxyribonucleoside breakdown" EXACT [] +synonym: "pyrimidine deoxyribonucleoside catabolism" EXACT [] +synonym: "pyrimidine deoxyribonucleoside degradation" EXACT [] +is_a: GO:0046121 ! deoxyribonucleoside catabolic process +is_a: GO:0046125 ! pyrimidine deoxyribonucleoside metabolic process +is_a: GO:0046135 ! pyrimidine nucleoside catabolic process + +[Term] +id: GO:0046128 +name: purine ribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "purine ribonucleoside metabolism" EXACT [] +is_a: GO:0009119 ! ribonucleoside metabolic process +is_a: GO:0042278 ! purine nucleoside metabolic process + +[Term] +id: GO:0046129 +name: purine ribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "purine ribonucleoside anabolism" EXACT [] +synonym: "purine ribonucleoside biosynthesis" EXACT [] +synonym: "purine ribonucleoside formation" EXACT [] +synonym: "purine ribonucleoside synthesis" EXACT [] +is_a: GO:0042451 ! purine nucleoside biosynthetic process +is_a: GO:0042455 ! ribonucleoside biosynthetic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0046130 +name: purine ribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "purine ribonucleoside breakdown" EXACT [] +synonym: "purine ribonucleoside catabolism" EXACT [] +synonym: "purine ribonucleoside degradation" EXACT [] +is_a: GO:0006152 ! purine nucleoside catabolic process +is_a: GO:0042454 ! ribonucleoside catabolic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0046131 +name: pyrimidine ribonucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "pyrimidine ribonucleoside metabolism" EXACT [] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0009119 ! ribonucleoside metabolic process + +[Term] +id: GO:0046132 +name: pyrimidine ribonucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "pyrimidine ribonucleoside anabolism" EXACT [] +synonym: "pyrimidine ribonucleoside biosynthesis" EXACT [] +synonym: "pyrimidine ribonucleoside formation" EXACT [] +synonym: "pyrimidine ribonucleoside synthesis" EXACT [] +is_a: GO:0042455 ! ribonucleoside biosynthetic process +is_a: GO:0046131 ! pyrimidine ribonucleoside metabolic process +is_a: GO:0046134 ! pyrimidine nucleoside biosynthetic process + +[Term] +id: GO:0046133 +name: pyrimidine ribonucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule." [GOC:ai] +synonym: "pyrimidine ribonucleoside breakdown" EXACT [] +synonym: "pyrimidine ribonucleoside catabolism" EXACT [] +synonym: "pyrimidine ribonucleoside degradation" EXACT [] +is_a: GO:0042454 ! ribonucleoside catabolic process +is_a: GO:0046131 ! pyrimidine ribonucleoside metabolic process +is_a: GO:0046135 ! pyrimidine nucleoside catabolic process + +[Term] +id: GO:0046134 +name: pyrimidine nucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "pyrimidine nucleoside anabolism" EXACT [] +synonym: "pyrimidine nucleoside biosynthesis" EXACT [] +synonym: "pyrimidine nucleoside formation" EXACT [] +synonym: "pyrimidine nucleoside synthesis" EXACT [] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0009163 ! nucleoside biosynthetic process +is_a: GO:0072528 ! pyrimidine-containing compound biosynthetic process + +[Term] +id: GO:0046135 +name: pyrimidine nucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)." [GOC:ai] +synonym: "pyrimidine nucleoside breakdown" EXACT [] +synonym: "pyrimidine nucleoside catabolism" EXACT [] +synonym: "pyrimidine nucleoside degradation" EXACT [] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0009164 ! nucleoside catabolic process +is_a: GO:0072529 ! pyrimidine-containing compound catabolic process + +[Term] +id: GO:0046136 +name: positive regulation of vitamin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] +synonym: "activation of vitamin metabolic process" NARROW [] +synonym: "positive regulation of vitamin metabolism" EXACT [] +synonym: "stimulation of vitamin metabolic process" NARROW [] +synonym: "up regulation of vitamin metabolic process" EXACT [] +synonym: "up-regulation of vitamin metabolic process" EXACT [] +synonym: "upregulation of vitamin metabolic process" EXACT [] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006766 ! vitamin metabolic process +relationship: positively_regulates GO:0006766 ! vitamin metabolic process + +[Term] +id: GO:0046137 +name: negative regulation of vitamin metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] +synonym: "down regulation of vitamin metabolic process" EXACT [] +synonym: "down-regulation of vitamin metabolic process" EXACT [] +synonym: "downregulation of vitamin metabolic process" EXACT [] +synonym: "inhibition of vitamin metabolic process" NARROW [] +synonym: "negative regulation of vitamin metabolism" EXACT [] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006766 ! vitamin metabolic process +relationship: negatively_regulates GO:0006766 ! vitamin metabolic process + +[Term] +id: GO:0046138 +name: obsolete coenzyme and prosthetic group biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "coenzyme and prosthetic group anabolism" EXACT [] +synonym: "coenzyme and prosthetic group biosynthesis" EXACT [] +synonym: "coenzyme and prosthetic group biosynthetic process" EXACT [] +synonym: "coenzyme and prosthetic group formation" EXACT [] +synonym: "coenzyme and prosthetic group synthesis" EXACT [] +is_obsolete: true +consider: GO:0009108 +consider: GO:0051191 + +[Term] +id: GO:0046139 +name: obsolete coenzyme and prosthetic group catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "coenzyme and prosthetic group breakdown" EXACT [] +synonym: "coenzyme and prosthetic group catabolic process" EXACT [] +synonym: "coenzyme and prosthetic group catabolism" EXACT [] +synonym: "coenzyme and prosthetic group degradation" EXACT [] +is_obsolete: true +consider: GO:0009109 +consider: GO:0051190 + +[Term] +id: GO:0046140 +name: corrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule." [GOC:ai] +synonym: "corrin anabolism" EXACT [] +synonym: "corrin biosynthesis" EXACT [] +synonym: "corrin formation" EXACT [] +synonym: "corrin synthesis" EXACT [] +is_a: GO:0015009 ! corrin metabolic process +is_a: GO:0033014 ! tetrapyrrole biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process + +[Term] +id: GO:0046141 +name: corrin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule." [GOC:ai] +synonym: "corrin breakdown" EXACT [] +synonym: "corrin catabolism" EXACT [] +synonym: "corrin degradation" EXACT [] +is_a: GO:0015009 ! corrin metabolic process +is_a: GO:0033015 ! tetrapyrrole catabolic process +is_a: GO:0051187 ! cofactor catabolic process + +[Term] +id: GO:0046142 +name: obsolete negative regulation of coenzyme and prosthetic group metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "negative regulation of coenzyme and prosthetic group metabolic process" EXACT [] +is_obsolete: true +consider: GO:0051198 +consider: GO:0051201 + +[Term] +id: GO:0046143 +name: obsolete positive regulation of coenzyme and prosthetic group metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups." [GOC:ai] +comment: This term was made obsolete because it was replaced by more specific terms. +synonym: "positive regulation of coenzyme and prosthetic group metabolic process" EXACT [] +is_obsolete: true +consider: GO:0051197 +consider: GO:0051200 + +[Term] +id: GO:0046144 +name: D-alanine family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-alanine and related amino acids." [GOC:ai] +synonym: "D-alanine family amino acid metabolism" EXACT [] +is_a: GO:0006522 ! alanine metabolic process + +[Term] +id: GO:0046145 +name: D-alanine family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids." [GOC:ai] +synonym: "D-alanine family amino acid anabolism" EXACT [] +synonym: "D-alanine family amino acid biosynthesis" EXACT [] +synonym: "D-alanine family amino acid formation" EXACT [] +synonym: "D-alanine family amino acid synthesis" EXACT [] +is_a: GO:0006523 ! alanine biosynthetic process +is_a: GO:0046144 ! D-alanine family amino acid metabolic process + +[Term] +id: GO:0046146 +name: tetrahydrobiopterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine." [PMID:21871890] +synonym: "5,6,7,8-tetrahydrobiopterin metabolic process" EXACT [GOC:curators] +synonym: "tetrahydrobiopterin metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process + +[Term] +id: GO:0046147 +name: tetrahydrobiopterin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine." [ISBN:0198506732] +synonym: "5,6,7,8-tetrahydrobiopterin catabolic process" EXACT [Wikipedia:Tetrahydrobiopterin] +synonym: "tetrahydrobiopterin breakdown" EXACT [] +synonym: "tetrahydrobiopterin catabolism" EXACT [] +synonym: "tetrahydrobiopterin degradation" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0042560 ! pteridine-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046146 ! tetrahydrobiopterin metabolic process + +[Term] +id: GO:0046148 +name: pigment biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin." [ISBN:0198506732] +synonym: "pigment anabolism" EXACT [] +synonym: "pigment biosynthesis" EXACT [] +synonym: "pigment formation" EXACT [] +synonym: "pigment synthesis" EXACT [] +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0046149 +name: pigment catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin." [ISBN:0198506732] +synonym: "pigment breakdown" EXACT [] +synonym: "pigment catabolism" EXACT [] +synonym: "pigment degradation" EXACT [] +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0046150 +name: melanin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom." [ISBN:0198506732] +synonym: "melanin breakdown" EXACT [] +synonym: "melanin catabolism" EXACT [] +synonym: "melanin degradation" EXACT [] +is_a: GO:0006582 ! melanin metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0046149 ! pigment catabolic process + +[Term] +id: GO:0046151 +name: eye pigment catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye." [GOC:ai] +synonym: "eye pigment breakdown" EXACT [] +synonym: "eye pigment catabolism" EXACT [] +synonym: "eye pigment degradation" EXACT [] +is_a: GO:0042441 ! eye pigment metabolic process +is_a: GO:0046149 ! pigment catabolic process + +[Term] +id: GO:0046152 +name: ommochrome metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye." [ISBN:0198506732] +synonym: "ommochrome metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0042441 ! eye pigment metabolic process +is_a: GO:0046158 ! ocellus pigment metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0046153 +name: ommochrome catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye." [ISBN:0198506732] +synonym: "ommochrome breakdown" EXACT [] +synonym: "ommochrome catabolism" EXACT [] +synonym: "ommochrome degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046151 ! eye pigment catabolic process +is_a: GO:0046152 ! ommochrome metabolic process +is_a: GO:0046159 ! ocellus pigment catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046154 +name: rhodopsin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas." [ISBN:0198506732] +synonym: "rhodopsin metabolism" EXACT [] +is_a: GO:0042441 ! eye pigment metabolic process +is_a: GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0046155 +name: rhodopsin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas." [ISBN:0198506732] +synonym: "rhodopsin breakdown" EXACT [] +synonym: "rhodopsin catabolism" EXACT [] +synonym: "rhodopsin degradation" EXACT [] +is_a: GO:0044257 ! cellular protein catabolic process +is_a: GO:0046151 ! eye pigment catabolic process +is_a: GO:0046154 ! rhodopsin metabolic process + +[Term] +id: GO:0046156 +name: siroheme metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings." [ISBN:0198506732] +synonym: "sirohaem metabolic process" EXACT [] +synonym: "sirohaem metabolism" EXACT [] +synonym: "siroheme metabolism" EXACT [] +is_a: GO:0042168 ! heme metabolic process + +[Term] +id: GO:0046157 +name: siroheme catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings." [ISBN:0198506732] +synonym: "sirohaem catabolic process" EXACT [] +synonym: "sirohaem catabolism" EXACT [] +synonym: "siroheme breakdown" EXACT [] +synonym: "siroheme catabolism" EXACT [] +synonym: "siroheme degradation" EXACT [] +is_a: GO:0042167 ! heme catabolic process +is_a: GO:0046156 ! siroheme metabolic process + +[Term] +id: GO:0046158 +name: ocellus pigment metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates." [GOC:ai, PMID:15176085, PMID:18421706] +synonym: "ocellus pigment metabolism" EXACT [] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0043474 ! pigment metabolic process involved in pigmentation +relationship: part_of GO:0033060 ! ocellus pigmentation + +[Term] +id: GO:0046159 +name: ocellus pigment catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates." [GOC:ai, PMID:15176085, PMID:18421706] +synonym: "ocellus pigment breakdown" EXACT [] +synonym: "ocellus pigment catabolism" EXACT [] +synonym: "ocellus pigment degradation" EXACT [] +is_a: GO:0046149 ! pigment catabolic process +is_a: GO:0046158 ! ocellus pigment metabolic process + +[Term] +id: GO:0046160 +name: heme a metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3." [GOC:curators] +synonym: "haem a metabolic process" EXACT [] +synonym: "haem a metabolism" EXACT [] +synonym: "heme a metabolism" EXACT [] +is_a: GO:0042168 ! heme metabolic process + +[Term] +id: GO:0046161 +name: heme a catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3." [GOC:curators, PMID:28352909] +synonym: "haem a catabolic process" EXACT [] +synonym: "haem a catabolism" EXACT [] +synonym: "heme a breakdown" EXACT [] +synonym: "heme a catabolism" EXACT [] +synonym: "heme a degradation" EXACT [] +is_a: GO:0042167 ! heme catabolic process +is_a: GO:0046160 ! heme a metabolic process + +[Term] +id: GO:0046162 +name: heme C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f." [GOC:curators] +synonym: "haem C metabolic process" EXACT [] +synonym: "haem C metabolism" EXACT [] +synonym: "heme C metabolism" EXACT [] +is_a: GO:0042168 ! heme metabolic process + +[Term] +id: GO:0046163 +name: heme C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f." [GOC:curators] +synonym: "haem C catabolic process" EXACT [] +synonym: "haem C catabolism" EXACT [] +synonym: "heme C breakdown" EXACT [] +synonym: "heme C catabolism" EXACT [] +synonym: "heme C degradation" EXACT [] +is_a: GO:0042167 ! heme catabolic process +is_a: GO:0046162 ! heme C metabolic process + +[Term] +id: GO:0046164 +name: alcohol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [GOC:ai] +synonym: "alcohol breakdown" EXACT [] +synonym: "alcohol catabolism" EXACT [] +synonym: "alcohol degradation" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0046165 +name: alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." [GOC:ai] +synonym: "alcohol anabolism" EXACT [] +synonym: "alcohol biosynthesis" EXACT [] +synonym: "alcohol formation" EXACT [] +synonym: "alcohol synthesis" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0046166 +name: glyceraldehyde-3-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis." [GOC:ai] +synonym: "glyceraldehyde 3-phosphate biosynthesis" EXACT [] +synonym: "glyceraldehyde 3-phosphate biosynthetic process" EXACT [] +synonym: "glyceraldehyde-3-phosphate anabolism" EXACT [] +synonym: "glyceraldehyde-3-phosphate biosynthesis" EXACT [] +synonym: "glyceraldehyde-3-phosphate formation" EXACT [] +synonym: "glyceraldehyde-3-phosphate synthesis" EXACT [] +is_a: GO:0019682 ! glyceraldehyde-3-phosphate metabolic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0046167 +name: glycerol-3-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol." [GOC:ai] +synonym: "glycerol-3-phosphate anabolism" EXACT [] +synonym: "glycerol-3-phosphate biosynthesis" EXACT [] +synonym: "glycerol-3-phosphate formation" EXACT [] +synonym: "glycerol-3-phosphate synthesis" EXACT [] +is_a: GO:0006072 ! glycerol-3-phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0046168 +name: glycerol-3-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol." [GOC:ai] +synonym: "glycerol-3-phosphate breakdown" EXACT [] +synonym: "glycerol-3-phosphate catabolism" EXACT [] +synonym: "glycerol-3-phosphate degradation" EXACT [] +is_a: GO:0006072 ! glycerol-3-phosphate metabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0046169 +name: methanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent." [GOC:ai] +synonym: "methanol anabolism" EXACT [] +synonym: "methanol biosynthesis" EXACT [] +synonym: "methanol formation" EXACT [] +synonym: "methanol synthesis" EXACT [] +is_a: GO:0015945 ! methanol metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process + +[Term] +id: GO:0046170 +name: methanol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent." [GOC:ai] +synonym: "methanol breakdown" EXACT [] +synonym: "methanol catabolism" EXACT [] +synonym: "methanol degradation" EXACT [] +is_a: GO:0015945 ! methanol metabolic process +is_a: GO:0034310 ! primary alcohol catabolic process + +[Term] +id: GO:0046171 +name: octanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH." [GOC:ai] +synonym: "octanol anabolism" EXACT [] +synonym: "octanol biosynthesis" EXACT [] +synonym: "octanol formation" EXACT [] +synonym: "octanol synthesis" EXACT [] +is_a: GO:0006070 ! octanol metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:1903175 ! fatty alcohol biosynthetic process + +[Term] +id: GO:0046172 +name: octanol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH." [GOC:ai] +synonym: "octanol breakdown" EXACT [] +synonym: "octanol catabolism" EXACT [] +synonym: "octanol degradation" EXACT [] +is_a: GO:0006070 ! octanol metabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:1903174 ! fatty alcohol catabolic process + +[Term] +id: GO:0046173 +name: polyol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms." [GOC:curators] +synonym: "polyhydric alcohol biosynthetic process" EXACT [] +synonym: "polyol anabolism" EXACT [] +synonym: "polyol biosynthesis" EXACT [] +synonym: "polyol formation" EXACT [] +synonym: "polyol synthesis" EXACT [] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0046165 ! alcohol biosynthetic process + +[Term] +id: GO:0046174 +name: polyol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms." [GOC:curators] +synonym: "polyhydric alcohol catabolic process" EXACT [] +synonym: "polyol breakdown" EXACT [] +synonym: "polyol catabolism" EXACT [] +synonym: "polyol degradation" EXACT [] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0046164 ! alcohol catabolic process + +[Term] +id: GO:0046175 +name: aldonic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group." [ISBN:0198506732] +synonym: "aldonic acid anabolism" EXACT [] +synonym: "aldonic acid biosynthesis" EXACT [] +synonym: "aldonic acid formation" EXACT [] +synonym: "aldonic acid synthesis" EXACT [] +is_a: GO:0019520 ! aldonic acid metabolic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046176 +name: aldonic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group." [ISBN:0198506732] +synonym: "aldonic acid breakdown" EXACT [] +synonym: "aldonic acid catabolism" EXACT [] +synonym: "aldonic acid degradation" EXACT [] +is_a: GO:0019520 ! aldonic acid metabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046177 +name: D-gluconate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "D-gluconate breakdown" EXACT [] +synonym: "D-gluconate catabolism" EXACT [] +synonym: "D-gluconate degradation" EXACT [] +xref: MetaCyc:GLUCONSUPER-PWY +is_a: GO:0019521 ! D-gluconate metabolic process +is_a: GO:0046176 ! aldonic acid catabolic process + +[Term] +id: GO:0046178 +name: D-gluconate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "D-gluconate anabolism" EXACT [] +synonym: "D-gluconate biosynthesis" EXACT [] +synonym: "D-gluconate formation" EXACT [] +synonym: "D-gluconate synthesis" EXACT [] +is_a: GO:0019521 ! D-gluconate metabolic process +is_a: GO:0046175 ! aldonic acid biosynthetic process + +[Term] +id: GO:0046179 +name: keto-D-gluconate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose." [ISBN:0198506732] +synonym: "keto-D-gluconate anabolism" EXACT [] +synonym: "keto-D-gluconate biosynthesis" EXACT [] +synonym: "keto-D-gluconate formation" EXACT [] +synonym: "keto-D-gluconate synthesis" EXACT [] +is_a: GO:0019525 ! keto-D-gluconate metabolic process +is_a: GO:0046180 ! ketogluconate biosynthetic process + +[Term] +id: GO:0046180 +name: ketogluconate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group." [ISBN:0198506732] +synonym: "ketogluconate anabolism" EXACT [] +synonym: "ketogluconate biosynthesis" EXACT [] +synonym: "ketogluconate formation" EXACT [] +synonym: "ketogluconate synthesis" EXACT [] +is_a: GO:0019522 ! ketogluconate metabolic process +is_a: GO:0046175 ! aldonic acid biosynthetic process + +[Term] +id: GO:0046181 +name: ketogluconate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group." [ISBN:0198506732] +synonym: "ketogluconate breakdown" EXACT [] +synonym: "ketogluconate catabolism" EXACT [] +synonym: "ketogluconate degradation" EXACT [] +is_a: GO:0019522 ! ketogluconate metabolic process +is_a: GO:0046176 ! aldonic acid catabolic process + +[Term] +id: GO:0046182 +name: L-idonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:curators] +synonym: "L-idonate anabolism" EXACT [] +synonym: "L-idonate biosynthesis" EXACT [] +synonym: "L-idonate formation" EXACT [] +synonym: "L-idonate synthesis" EXACT [] +is_a: GO:0019523 ! L-idonate metabolic process +is_a: GO:0046175 ! aldonic acid biosynthetic process + +[Term] +id: GO:0046183 +name: L-idonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:curators] +synonym: "L-idonate breakdown" EXACT [] +synonym: "L-idonate catabolism" EXACT [] +synonym: "L-idonate degradation" EXACT [] +is_a: GO:0019523 ! L-idonate metabolic process +is_a: GO:0046176 ! aldonic acid catabolic process + +[Term] +id: GO:0046184 +name: aldehyde biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O." [GOC:ai] +synonym: "aldehyde anabolism" EXACT [] +synonym: "aldehyde biosynthesis" EXACT [] +synonym: "aldehyde formation" EXACT [] +synonym: "aldehyde synthesis" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0046185 +name: aldehyde catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O." [GOC:ai] +synonym: "aldehyde breakdown" EXACT [] +synonym: "aldehyde catabolism" EXACT [] +synonym: "aldehyde degradation" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046186 +name: acetaldehyde biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol." [GOC:ai] +synonym: "acetaldehyde anabolism" EXACT [] +synonym: "acetaldehyde biosynthesis" EXACT [] +synonym: "acetaldehyde formation" EXACT [] +synonym: "acetaldehyde synthesis" EXACT [] +is_a: GO:0006117 ! acetaldehyde metabolic process +is_a: GO:0046184 ! aldehyde biosynthetic process + +[Term] +id: GO:0046187 +name: acetaldehyde catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol." [GOC:ai] +synonym: "acetaldehyde breakdown" EXACT [] +synonym: "acetaldehyde catabolism" EXACT [] +synonym: "acetaldehyde degradation" EXACT [] +is_a: GO:0006117 ! acetaldehyde metabolic process +is_a: GO:0046185 ! aldehyde catabolic process + +[Term] +id: GO:0046188 +name: methane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes." [GOC:ai] +synonym: "methane breakdown" EXACT [] +synonym: "methane catabolism" EXACT [] +synonym: "methane degradation" EXACT [] +is_a: GO:0015947 ! methane metabolic process +is_a: GO:0043448 ! alkane catabolic process + +[Term] +id: GO:0046189 +name: phenol-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai] +synonym: "phenol-containing compound anabolism" EXACT [] +synonym: "phenol-containing compound biosynthesis" EXACT [] +synonym: "phenol-containing compound formation" EXACT [] +synonym: "phenol-containing compound synthesis" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0046190 +name: aerobic phenol-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen." [GOC:ai] +synonym: "aerobic phenol-containing compound anabolism" EXACT [] +synonym: "aerobic phenol-containing compound biosynthesis" EXACT [] +synonym: "aerobic phenol-containing compound formation" EXACT [] +synonym: "aerobic phenol-containing compound synthesis" EXACT [] +is_a: GO:0018959 ! aerobic phenol-containing compound metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0046191 +name: aerobic phenol-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen." [GOC:ai] +synonym: "aerobic phenol-containing compound breakdown" EXACT [] +synonym: "aerobic phenol-containing compound catabolism" EXACT [] +synonym: "aerobic phenol-containing compound degradation" EXACT [] +is_a: GO:0018959 ! aerobic phenol-containing compound metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process + +[Term] +id: GO:0046192 +name: anaerobic phenol-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen." [GOC:ai] +synonym: "anaerobic phenol-containing compound anabolism" EXACT [] +synonym: "anaerobic phenol-containing compound biosynthesis" EXACT [] +synonym: "anaerobic phenol-containing compound formation" EXACT [] +synonym: "anaerobic phenol-containing compound synthesis" EXACT [] +is_a: GO:0042215 ! anaerobic phenol-containing compound metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0046193 +name: anaerobic phenol-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen." [GOC:ai] +synonym: "anaerobic phenol-containing compound breakdown" EXACT [] +synonym: "anaerobic phenol-containing compound catabolism" EXACT [] +synonym: "anaerobic phenol-containing compound degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042215 ! anaerobic phenol-containing compound metabolic process + +[Term] +id: GO:0046194 +name: obsolete pentachlorophenol biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms." [GOC:ai] +comment: This term was made obsolete because pentachlorophenol is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "pentachlorophenol anabolism" EXACT [] +synonym: "pentachlorophenol biosynthesis" EXACT [] +synonym: "pentachlorophenol biosynthetic process" EXACT [] +synonym: "pentachlorophenol formation" EXACT [] +synonym: "pentachlorophenol synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018961 + +[Term] +id: GO:0046195 +name: obsolete 4-nitrophenol biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion." [GOC:ai] +comment: This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "4-nitrophenol anabolism" EXACT [] +synonym: "4-nitrophenol biosynthesis" EXACT [] +synonym: "4-nitrophenol biosynthetic process" EXACT [] +synonym: "4-nitrophenol formation" EXACT [] +synonym: "4-nitrophenol synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018960 + +[Term] +id: GO:0046196 +name: 4-nitrophenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion." [GOC:ai] +synonym: "4-nitrophenol breakdown" EXACT [] +synonym: "4-nitrophenol catabolism" EXACT [] +synonym: "4-nitrophenol degradation" EXACT [] +is_a: GO:0018960 ! 4-nitrophenol metabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process + +[Term] +id: GO:0046197 +name: orcinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants." [GOC:ai] +synonym: "orcinol anabolism" EXACT [] +synonym: "orcinol biosynthesis" EXACT [] +synonym: "orcinol formation" EXACT [] +synonym: "orcinol synthesis" EXACT [] +is_a: GO:0018940 ! orcinol metabolic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process + +[Term] +id: GO:0046198 +name: obsolete cresol biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote." [GOC:ai] +comment: This term was made obsolete because cresol is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "cresol anabolism" EXACT [] +synonym: "cresol biosynthesis" EXACT [] +synonym: "cresol biosynthetic process" EXACT [] +synonym: "cresol formation" EXACT [] +synonym: "cresol synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0042212 + +[Term] +id: GO:0046199 +name: cresol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote." [GOC:ai] +synonym: "cresol breakdown" EXACT [] +synonym: "cresol catabolism" EXACT [] +synonym: "cresol degradation" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042212 ! cresol metabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0046200 +name: obsolete m-cresol biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of m-cresol (3-hydroxytoluene), the meta-isoform of cresol." [GOC:ai] +comment: This term was made obsolete because m-cresol is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "m-cresol anabolism" EXACT [] +synonym: "m-cresol biosynthesis" EXACT [] +synonym: "m-cresol biosynthetic process" EXACT [] +synonym: "m-cresol formation" EXACT [] +synonym: "m-cresol synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018925 + +[Term] +id: GO:0046201 +name: cyanate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid." [GOC:ai] +synonym: "cyanate anabolism" EXACT [] +synonym: "cyanate biosynthesis" EXACT [] +synonym: "cyanate formation" EXACT [] +synonym: "cyanate synthesis" EXACT [] +is_a: GO:0009439 ! cyanate metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0046202 +name: cyanide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration." [GOC:ai] +synonym: "cyanide anabolism" EXACT [] +synonym: "cyanide biosynthesis" EXACT [] +synonym: "cyanide formation" EXACT [] +synonym: "cyanide synthesis" EXACT [] +is_a: GO:0019499 ! cyanide metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0046203 +name: spermidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] +synonym: "spermidine breakdown" EXACT [] +synonym: "spermidine catabolism" EXACT [] +synonym: "spermidine degradation" EXACT [] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:0008216 ! spermidine metabolic process + +[Term] +id: GO:0046204 +name: nor-spermidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] +synonym: "nor-spermidine metabolism" EXACT [] +is_a: GO:0006595 ! polyamine metabolic process + +[Term] +id: GO:0046205 +name: nor-spermidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] +synonym: "nor-spermidine breakdown" EXACT [] +synonym: "nor-spermidine catabolism" EXACT [] +synonym: "nor-spermidine degradation" EXACT [] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:0046204 ! nor-spermidine metabolic process + +[Term] +id: GO:0046206 +name: trypanothione metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress." [GOC:ai] +synonym: "trypanothione metabolism" EXACT [] +is_a: GO:1901685 ! glutathione derivative metabolic process + +[Term] +id: GO:0046207 +name: trypanothione catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress." [GOC:ai] +synonym: "trypanothione breakdown" EXACT [] +synonym: "trypanothione catabolism" EXACT [] +synonym: "trypanothione degradation" EXACT [] +is_a: GO:0046206 ! trypanothione metabolic process +is_a: GO:1901686 ! glutathione derivative catabolic process + +[Term] +id: GO:0046208 +name: spermine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging." [PMID:12141946] +synonym: "spermine breakdown" EXACT [] +synonym: "spermine catabolism" EXACT [] +synonym: "spermine degradation" EXACT [] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:0008215 ! spermine metabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0046209 +name: nitric oxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] +synonym: "nitric oxide metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0072593 ! reactive oxygen species metabolic process +is_a: GO:2001057 ! reactive nitrogen species metabolic process + +[Term] +id: GO:0046210 +name: nitric oxide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] +synonym: "nitric oxide breakdown" EXACT [] +synonym: "nitric oxide catabolism" EXACT [] +synonym: "nitric oxide degradation" EXACT [] +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046209 ! nitric oxide metabolic process + +[Term] +id: GO:0046211 +name: (+)-camphor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone." [GOC:ai] +synonym: "(+)-camphor anabolism" EXACT [] +synonym: "(+)-camphor biosynthesis" EXACT [] +synonym: "(+)-camphor formation" EXACT [] +synonym: "(+)-camphor synthesis" EXACT [] +is_a: GO:0016099 ! monoterpenoid biosynthetic process +is_a: GO:0018882 ! (+)-camphor metabolic process +is_a: GO:0042181 ! ketone biosynthetic process + +[Term] +id: GO:0046212 +name: obsolete methyl ethyl ketone biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints." [GOC:ai] +comment: This term was made obsolete because methyl ethyl ketone is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "methyl ethyl ketone anabolism" EXACT [] +synonym: "methyl ethyl ketone biosynthesis" EXACT [] +synonym: "methyl ethyl ketone biosynthetic process" EXACT [] +synonym: "methyl ethyl ketone formation" EXACT [] +synonym: "methyl ethyl ketone synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018928 + +[Term] +id: GO:0046213 +name: methyl ethyl ketone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor." [GOC:ai] +synonym: "methyl ethyl ketone breakdown" EXACT [] +synonym: "methyl ethyl ketone catabolism" EXACT [] +synonym: "methyl ethyl ketone degradation" EXACT [] +is_a: GO:0018928 ! methyl ethyl ketone metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042182 ! ketone catabolic process + +[Term] +id: GO:0046214 +name: enterobactin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway." [GOC:ai] +synonym: "enterobactin breakdown" EXACT [] +synonym: "enterobactin catabolism" EXACT [] +synonym: "enterobactin degradation" EXACT [] +is_a: GO:0009238 ! enterobactin metabolic process +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0046215 ! siderophore catabolic process +is_a: GO:0046700 ! heterocycle catabolic process + +[Term] +id: GO:0046215 +name: siderophore catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action." [GOC:ai] +synonym: "siderochrome catabolism" NARROW [] +synonym: "siderophore breakdown" EXACT [] +synonym: "siderophore catabolism" EXACT [] +synonym: "siderophore degradation" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process + +[Term] +id: GO:0046216 +name: indole phytoalexin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response." [GOC:ai] +synonym: "indole phytoalexin breakdown" EXACT [] +synonym: "indole phytoalexin catabolism" EXACT [] +synonym: "indole phytoalexin degradation" EXACT [] +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:0046217 ! indole phytoalexin metabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:0052316 ! phytoalexin catabolic process + +[Term] +id: GO:0046217 +name: indole phytoalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response." [GOC:ai] +synonym: "indole phytoalexin metabolism" EXACT [] +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0046218 +name: indolalkylamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] +synonym: "indolalkylamine breakdown" EXACT [] +synonym: "indolalkylamine catabolism" EXACT [] +synonym: "indolalkylamine degradation" EXACT [] +is_a: GO:0006586 ! indolalkylamine metabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:0042436 ! indole-containing compound catabolic process + +[Term] +id: GO:0046219 +name: indolalkylamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] +synonym: "indolalkylamine anabolism" EXACT [] +synonym: "indolalkylamine biosynthesis" EXACT [] +synonym: "indolalkylamine formation" EXACT [] +synonym: "indolalkylamine synthesis" EXACT [] +is_a: GO:0006586 ! indolalkylamine metabolic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process + +[Term] +id: GO:0046220 +name: pyridine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor." [GOC:ai] +synonym: "pyridine anabolism" EXACT [] +synonym: "pyridine biosynthesis" EXACT [] +synonym: "pyridine formation" EXACT [] +synonym: "pyridine synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0019507 ! pyridine metabolic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process + +[Term] +id: GO:0046221 +name: pyridine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor." [GOC:ai] +synonym: "pyridine breakdown" EXACT [] +synonym: "pyridine catabolism" EXACT [] +synonym: "pyridine degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0019507 ! pyridine metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process + +[Term] +id: GO:0046222 +name: aflatoxin metabolic process +namespace: biological_process +alt_id: GO:0043389 +alt_id: GO:0043390 +alt_id: GO:0043391 +def: "The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450." [GOC:ai] +synonym: "aflatoxin B metabolic process" NARROW [GOC:mah] +synonym: "aflatoxin B1 metabolic process" RELATED [] +synonym: "aflatoxin B1 metabolism" RELATED [] +synonym: "aflatoxin B2 metabolic process" RELATED [] +synonym: "aflatoxin B2 metabolism" RELATED [] +synonym: "aflatoxin metabolism" EXACT [] +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18291 xsd:anyURI + +[Term] +id: GO:0046223 +name: aflatoxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450." [GOC:ai] +synonym: "aflatoxin breakdown" EXACT [] +synonym: "aflatoxin catabolism" EXACT [] +synonym: "aflatoxin degradation" EXACT [] +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0046222 ! aflatoxin metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process + +[Term] +id: GO:0046224 +name: bacteriocin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary." [GOC:ai] +synonym: "bacteriocin metabolism" EXACT [] +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0030650 ! peptide antibiotic metabolic process + +[Term] +id: GO:0046225 +name: bacteriocin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary." [GOC:ai] +synonym: "bacteriocin breakdown" EXACT [] +synonym: "bacteriocin catabolism" EXACT [] +synonym: "bacteriocin degradation" EXACT [] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0030652 ! peptide antibiotic catabolic process +is_a: GO:0046224 ! bacteriocin metabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound + +[Term] +id: GO:0046226 +name: coumarin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids." [GOC:ai] +synonym: "coumarin breakdown" EXACT [] +synonym: "coumarin catabolism" EXACT [] +synonym: "coumarin degradation" EXACT [] +is_a: GO:0009804 ! coumarin metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process + +[Term] +id: GO:0046227 +name: obsolete 2,4,5-trichlorophenoxyacetic acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide." [GOC:ai] +comment: This term was made obsolete because 2,4,5-trichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "2,4,5-trichlorophenoxyacetic acid anabolism" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid biosynthesis" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid biosynthetic process" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid formation" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018980 + +[Term] +id: GO:0046228 +name: 2,4,5-trichlorophenoxyacetic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide." [GOC:ai] +synonym: "2,4,5-trichlorophenoxyacetic acid breakdown" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid catabolism" EXACT [] +synonym: "2,4,5-trichlorophenoxyacetic acid degradation" EXACT [] +is_a: GO:0009852 ! auxin catabolic process +is_a: GO:0018980 ! 2,4,5-trichlorophenoxyacetic acid metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0046229 +name: obsolete 2-aminobenzenesulfonate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [GOC:ai] +comment: This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "2-aminobenzenesulfonate anabolism" EXACT [] +synonym: "2-aminobenzenesulfonate biosynthesis" EXACT [] +synonym: "2-aminobenzenesulfonate biosynthetic process" EXACT [] +synonym: "2-aminobenzenesulfonate formation" EXACT [] +synonym: "2-aminobenzenesulfonate synthesis" EXACT [] +synonym: "2-aminobenzenesulphonate biosynthesis" EXACT [] +synonym: "2-aminobenzenesulphonate biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0018868 + +[Term] +id: GO:0046230 +name: 2-aminobenzenesulfonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [GOC:ai] +synonym: "2-aminobenzenesulfonate breakdown" EXACT [] +synonym: "2-aminobenzenesulfonate catabolism" EXACT [] +synonym: "2-aminobenzenesulfonate degradation" EXACT [] +synonym: "2-aminobenzenesulphonate catabolic process" EXACT [] +synonym: "2-aminobenzenesulphonate catabolism" EXACT [] +is_a: GO:0009310 ! amine catabolic process +is_a: GO:0016054 ! organic acid catabolic process +is_a: GO:0018868 ! 2-aminobenzenesulfonate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046231 +name: obsolete carbazole biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen." [GOC:ai] +comment: This term was made obsolete because carbazole is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "carbazole anabolism" EXACT [] +synonym: "carbazole biosynthesis" EXACT [] +synonym: "carbazole biosynthetic process" EXACT [] +synonym: "carbazole formation" EXACT [] +synonym: "carbazole synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018884 + +[Term] +id: GO:0046232 +name: carbazole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen." [GOC:ai] +synonym: "carbazole breakdown" EXACT [] +synonym: "carbazole catabolism" EXACT [] +synonym: "carbazole degradation" EXACT [] +is_a: GO:0018884 ! carbazole metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0046233 +name: obsolete 3-hydroxyphenylacetate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate." [GOC:curator] +comment: This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "3-hydroxyphenylacetate anabolism" EXACT [] +synonym: "3-hydroxyphenylacetate biosynthesis" EXACT [] +synonym: "3-hydroxyphenylacetate biosynthetic process" EXACT [] +synonym: "3-hydroxyphenylacetate formation" EXACT [] +synonym: "3-hydroxyphenylacetate synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0019609 + +[Term] +id: GO:0046234 +name: obsolete fluorene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents." [GOC:ai] +comment: This term was made obsolete because fluorene is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "fluorene anabolism" EXACT [] +synonym: "fluorene biosynthesis" EXACT [] +synonym: "fluorene biosynthetic process" EXACT [] +synonym: "fluorene formation" EXACT [] +synonym: "fluorene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018917 + +[Term] +id: GO:0046235 +name: gallate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid)." [GOC:ai] +synonym: "gallate anabolism" EXACT [] +synonym: "gallate biosynthesis" EXACT [] +synonym: "gallate formation" EXACT [] +synonym: "gallate synthesis" EXACT [] +synonym: "gallic acid biosynthesis" EXACT [] +synonym: "gallic acid biosynthetic process" EXACT [] +is_a: GO:0018918 ! gallate metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046236 +name: mandelate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic." [GOC:ai] +synonym: "mandelate anabolism" EXACT [] +synonym: "mandelate biosynthesis" EXACT [] +synonym: "mandelate formation" EXACT [] +synonym: "mandelate synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018924 ! mandelate metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0046237 +name: obsolete phenanthrene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of phenanthrene, a tricyclic aromatic hydrocarbon." [GOC:ai] +comment: This term was made obsolete because phenanthrene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "phenanthrene anabolism" EXACT [] +synonym: "phenanthrene biosynthesis" EXACT [] +synonym: "phenanthrene biosynthetic process" EXACT [] +synonym: "phenanthrene formation" EXACT [] +synonym: "phenanthrene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018955 + +[Term] +id: GO:0046238 +name: obsolete phthalate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of phthalate, any ester or salt of phthalic acid." [GOC:ai] +comment: This term was made obsolete because phthalates are not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "phthalate anabolism" EXACT [] +synonym: "phthalate biosynthesis" EXACT [] +synonym: "phthalate biosynthetic process" EXACT [] +synonym: "phthalate formation" EXACT [] +synonym: "phthalate synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018963 + +[Term] +id: GO:0046239 +name: phthalate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid." [GOC:ai] +synonym: "phthalate breakdown" EXACT [] +synonym: "phthalate catabolism" EXACT [] +synonym: "phthalate degradation" EXACT [] +is_a: GO:0018963 ! phthalate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046240 +name: obsolete xylene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene." [GOC:ai] +comment: This term was made obsolete because xylene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "xylene anabolism" EXACT [] +synonym: "xylene biosynthesis" EXACT [] +synonym: "xylene biosynthetic process" EXACT [] +synonym: "xylene formation" EXACT [] +synonym: "xylene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018948 + +[Term] +id: GO:0046241 +name: obsolete m-xylene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon." [GOC:ai] +comment: This term was made obsolete because m-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "m-xylene anabolism" EXACT [] +synonym: "m-xylene biosynthesis" EXACT [] +synonym: "m-xylene biosynthetic process" EXACT [] +synonym: "m-xylene formation" EXACT [] +synonym: "m-xylene synthesis" EXACT [] +synonym: "meta-xylene biosynthesis" EXACT [] +synonym: "meta-xylene biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0018949 + +[Term] +id: GO:0046242 +name: obsolete o-xylene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon." [GOC:ai] +comment: This term was made obsolete because o-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "o-xylene anabolism" EXACT [] +synonym: "o-xylene biosynthesis" EXACT [] +synonym: "o-xylene biosynthetic process" EXACT [] +synonym: "o-xylene formation" EXACT [] +synonym: "o-xylene synthesis" EXACT [] +synonym: "ortho-xylene biosynthesis" EXACT [] +synonym: "ortho-xylene biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0018950 + +[Term] +id: GO:0046243 +name: obsolete p-xylene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon." [GOC:ai] +comment: This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "p-xylene anabolism" EXACT [] +synonym: "p-xylene biosynthesis" EXACT [] +synonym: "p-xylene biosynthetic process" EXACT [] +synonym: "p-xylene formation" EXACT [] +synonym: "p-xylene synthesis" EXACT [] +synonym: "para-xylene biosynthesis" EXACT [] +synonym: "para-xylene biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0018951 + +[Term] +id: GO:0046244 +name: salicylic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid." [GOC:ai] +synonym: "salicylic acid breakdown" EXACT [] +synonym: "salicylic acid catabolism" EXACT [] +synonym: "salicylic acid degradation" EXACT [] +is_a: GO:0009696 ! salicylic acid metabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046245 +name: obsolete styrene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene." [GOC:ai] +comment: This term was made obsolete because styrene is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "styrene anabolism" EXACT [] +synonym: "styrene biosynthesis" EXACT [] +synonym: "styrene biosynthetic process" EXACT [] +synonym: "styrene formation" EXACT [] +synonym: "styrene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018966 + +[Term] +id: GO:0046246 +name: terpene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units." [GOC:ai] +synonym: "terpene anabolism" EXACT [] +synonym: "terpene biosynthesis" EXACT [] +synonym: "terpene formation" EXACT [] +synonym: "terpene synthesis" EXACT [] +is_a: GO:0008299 ! isoprenoid biosynthetic process +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0046247 +name: terpene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units." [GOC:ai] +synonym: "terpene breakdown" EXACT [] +synonym: "terpene catabolism" EXACT [] +synonym: "terpene degradation" EXACT [] +is_a: GO:0008300 ! isoprenoid catabolic process +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0046248 +name: alpha-pinene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature." [GOC:ai] +synonym: "alpha-pinene anabolism" EXACT [] +synonym: "alpha-pinene biosynthesis" EXACT [] +synonym: "alpha-pinene formation" EXACT [] +synonym: "alpha-pinene synthesis" EXACT [] +is_a: GO:0018867 ! alpha-pinene metabolic process +is_a: GO:0043693 ! monoterpene biosynthetic process + +[Term] +id: GO:0046249 +name: alpha-pinene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature." [GOC:ai] +synonym: "alpha-pinene breakdown" EXACT [] +synonym: "alpha-pinene catabolism" EXACT [] +synonym: "alpha-pinene degradation" EXACT [] +is_a: GO:0018867 ! alpha-pinene metabolic process +is_a: GO:0033074 ! pinene catabolic process + +[Term] +id: GO:0046250 +name: limonene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene." [GOC:ai] +synonym: "limonene anabolism" EXACT [] +synonym: "limonene biosynthesis" EXACT [] +synonym: "limonene formation" EXACT [] +synonym: "limonene synthesis" EXACT [] +is_a: GO:0018923 ! limonene metabolic process +is_a: GO:0043693 ! monoterpene biosynthetic process +is_a: GO:1900674 ! olefin biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0046251 +name: limonene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene." [GOC:ai] +synonym: "limonene breakdown" EXACT [] +synonym: "limonene catabolism" EXACT [] +synonym: "limonene degradation" EXACT [] +is_a: GO:0018923 ! limonene metabolic process +is_a: GO:0043694 ! monoterpene catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046252 +name: toluene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products." [GOC:ai, PMID:6508079] +comment: This term was reinstated from obsolete. +synonym: "toluene anabolism" EXACT [] +synonym: "toluene biosynthesis" EXACT [] +synonym: "toluene formation" EXACT [] +synonym: "toluene synthesis" EXACT [] +is_a: GO:0018970 ! toluene metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0046253 +name: anaerobic toluene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen." [GOC:ai, PMID:8573493] +comment: This term was reinstated from obsolete. +synonym: "anaerobic toluene anabolism" EXACT [] +synonym: "anaerobic toluene biosynthesis" EXACT [] +synonym: "anaerobic toluene formation" EXACT [] +synonym: "anaerobic toluene synthesis" EXACT [] +is_a: GO:0018971 ! anaerobic toluene metabolic process +is_a: GO:0046252 ! toluene biosynthetic process + +[Term] +id: GO:0046254 +name: anaerobic toluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen." [GOC:ai] +synonym: "anaerobic toluene breakdown" EXACT [] +synonym: "anaerobic toluene catabolism" EXACT [] +synonym: "anaerobic toluene degradation" EXACT [] +xref: MetaCyc:PWY-81 +is_a: GO:0042203 ! toluene catabolic process + +[Term] +id: GO:0046255 +name: obsolete 2,4,6-trinitrotoluene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene." [GOC:ai] +comment: This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "2,4,6-trinitrotoluene anabolism" EXACT [] +synonym: "2,4,6-trinitrotoluene biosynthesis" EXACT [] +synonym: "2,4,6-trinitrotoluene biosynthetic process" EXACT [] +synonym: "2,4,6-trinitrotoluene formation" EXACT [] +synonym: "2,4,6-trinitrotoluene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018974 + +[Term] +id: GO:0046256 +name: 2,4,6-trinitrotoluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid." [GOC:ai] +synonym: "2,4,6-trinitrotoluene breakdown" EXACT [] +synonym: "2,4,6-trinitrotoluene catabolism" EXACT [] +synonym: "2,4,6-trinitrotoluene degradation" EXACT [] +is_a: GO:0018974 ! 2,4,6-trinitrotoluene metabolic process +is_a: GO:0046260 ! trinitrotoluene catabolic process + +[Term] +id: GO:0046257 +name: obsolete anaerobic 2,4,6-trinitrotoluene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen." [GOC:ai] +comment: This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "anaerobic 2,4,6-trinitrotoluene anabolism" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene biosynthesis" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene biosynthetic process" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene formation" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018975 + +[Term] +id: GO:0046258 +name: anaerobic 2,4,6-trinitrotoluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen." [GOC:ai] +synonym: "anaerobic 2,4,6-trinitrotoluene breakdown" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene catabolism" EXACT [] +synonym: "anaerobic 2,4,6-trinitrotoluene degradation" EXACT [] +is_a: GO:0018975 ! anaerobic 2,4,6-trinitrotoluene metabolic process +is_a: GO:0046256 ! 2,4,6-trinitrotoluene catabolic process + +[Term] +id: GO:0046259 +name: obsolete trinitrotoluene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it." [GOC:ai] +comment: This term was made obsolete because trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "trinitrotoluene anabolism" EXACT [] +synonym: "trinitrotoluene biosynthesis" EXACT [] +synonym: "trinitrotoluene biosynthetic process" EXACT [] +synonym: "trinitrotoluene formation" EXACT [] +synonym: "trinitrotoluene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018973 + +[Term] +id: GO:0046260 +name: trinitrotoluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene." [GOC:ai] +synonym: "trinitrotoluene breakdown" EXACT [] +synonym: "trinitrotoluene catabolism" EXACT [] +synonym: "trinitrotoluene degradation" EXACT [] +is_a: GO:0018973 ! trinitrotoluene metabolic process +is_a: GO:0046263 ! nitrotoluene catabolic process + +[Term] +id: GO:0046261 +name: obsolete 4-nitrotoluene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene." [GOC:ai] +comment: This term was made obsolete because 4-nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "4-nitrotoluene anabolism" EXACT [] +synonym: "4-nitrotoluene biosynthesis" EXACT [] +synonym: "4-nitrotoluene biosynthetic process" EXACT [] +synonym: "4-nitrotoluene formation" EXACT [] +synonym: "4-nitrotoluene synthesis" EXACT [] +synonym: "4NT biosynthesis" EXACT [] +synonym: "4NT biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0019257 + +[Term] +id: GO:0046262 +name: obsolete nitrotoluene biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached." [GOC:ai] +comment: This term was made obsolete because nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "nitrotoluene anabolism" EXACT [] +synonym: "nitrotoluene biosynthesis" EXACT [] +synonym: "nitrotoluene biosynthetic process" EXACT [] +synonym: "nitrotoluene formation" EXACT [] +synonym: "nitrotoluene synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0019326 + +[Term] +id: GO:0046263 +name: nitrotoluene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached." [GOC:ai] +synonym: "nitrotoluene breakdown" EXACT [] +synonym: "nitrotoluene catabolism" EXACT [] +synonym: "nitrotoluene degradation" EXACT [] +is_a: GO:0019326 ! nitrotoluene metabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0046264 +name: obsolete thiocyanate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of thiocyanate, any anion or salt of thiocyanic acid." [GOC:ai] +comment: This term was made obsolete because thiocyanates are not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "thiocyanate anabolism" EXACT [] +synonym: "thiocyanate biosynthesis" EXACT [] +synonym: "thiocyanate biosynthetic process" EXACT [] +synonym: "thiocyanate formation" EXACT [] +synonym: "thiocyanate synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018969 + +[Term] +id: GO:0046265 +name: thiocyanate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid." [GOC:ai] +synonym: "thiocyanate breakdown" EXACT [] +synonym: "thiocyanate catabolism" EXACT [] +synonym: "thiocyanate degradation" EXACT [] +is_a: GO:0018969 ! thiocyanate metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046266 +name: obsolete triethanolamine biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent." [GOC:ai] +comment: This term was made obsolete because triethanolamine is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "triethanolamine anabolism" EXACT [] +synonym: "triethanolamine biosynthesis" EXACT [] +synonym: "triethanolamine biosynthetic process" EXACT [] +synonym: "triethanolamine formation" EXACT [] +synonym: "triethanolamine synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018981 + +[Term] +id: GO:0046267 +name: triethanolamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent." [GOC:ai] +synonym: "triethanolamine breakdown" EXACT [] +synonym: "triethanolamine catabolism" EXACT [] +synonym: "triethanolamine degradation" EXACT [] +is_a: GO:0018981 ! triethanolamine metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0046268 +name: obsolete toluene-4-sulfonate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule." [GOC:ai] +comment: This term was made obsolete because toluene-4-sulfonate is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "4-toluenesulfonate biosynthesis" EXACT [] +synonym: "4-toluenesulfonate biosynthetic process" EXACT [] +synonym: "toluene-4-sulfonate anabolism" EXACT [] +synonym: "toluene-4-sulfonate biosynthesis" EXACT [] +synonym: "toluene-4-sulfonate biosynthetic process" EXACT [] +synonym: "toluene-4-sulfonate formation" EXACT [] +synonym: "toluene-4-sulfonate synthesis" EXACT [] +synonym: "toluene-4-sulphonate biosynthesis" EXACT [] +synonym: "toluene-4-sulphonate biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0018972 + +[Term] +id: GO:0046269 +name: toluene-4-sulfonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule." [GOC:ai] +synonym: "4-toluenesulfonate catabolic process" EXACT [] +synonym: "4-toluenesulfonate catabolism" EXACT [] +synonym: "toluene-4-sulfonate breakdown" EXACT [] +synonym: "toluene-4-sulfonate catabolism" EXACT [] +synonym: "toluene-4-sulfonate degradation" EXACT [] +synonym: "toluene-4-sulphonate catabolic process" EXACT [] +synonym: "toluene-4-sulphonate catabolism" EXACT [] +is_a: GO:0016054 ! organic acid catabolic process +is_a: GO:0018972 ! toluene-4-sulfonate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0072491 ! toluene-containing compound catabolic process + +[Term] +id: GO:0046270 +name: obsolete 4-toluenecarboxylate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule." [GOC:ai] +comment: This term was made obsolete because 4-toluenecarboxylate is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "4-toluenecarboxylate anabolism" EXACT [] +synonym: "4-toluenecarboxylate biosynthesis" EXACT [] +synonym: "4-toluenecarboxylate biosynthetic process" EXACT [] +synonym: "4-toluenecarboxylate formation" EXACT [] +synonym: "4-toluenecarboxylate synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0019611 + +[Term] +id: GO:0046271 +name: phenylpropanoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid." [GOC:ai] +synonym: "phenylpropanoid breakdown" EXACT [] +synonym: "phenylpropanoid catabolism" EXACT [] +synonym: "phenylpropanoid degradation" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046272 +name: stilbene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA." [GOC:ai] +synonym: "stilbene breakdown" EXACT [] +synonym: "stilbene catabolism" EXACT [] +synonym: "stilbene degradation" EXACT [] +is_a: GO:0009810 ! stilbene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046273 +name: lignan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist." [GOC:jl, PMID:10074466] +synonym: "lignan breakdown" EXACT [] +synonym: "lignan catabolism" EXACT [] +synonym: "lignan degradation" EXACT [] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process + +[Term] +id: GO:0046274 +name: lignin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units." [GOC:ai] +synonym: "lignin breakdown" EXACT [] +synonym: "lignin catabolism" EXACT [] +synonym: "lignin degradation" EXACT [] +is_a: GO:0009808 ! lignin metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process + +[Term] +id: GO:0046275 +name: flavonoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton." [GOC:ai] +synonym: "flavonoid breakdown" EXACT [] +synonym: "flavonoid catabolism" EXACT [] +synonym: "flavonoid degradation" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046276 +name: methylgallate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid." [GOC:ai] +synonym: "methylgallate breakdown" EXACT [] +synonym: "methylgallate catabolism" EXACT [] +synonym: "methylgallate degradation" EXACT [] +xref: MetaCyc:METHYLGALLATE-DEGRADATION-PWY +is_a: GO:0019489 ! methylgallate metabolic process +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046277 +name: methylgallate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid." [GOC:ai] +synonym: "methylgallate anabolism" EXACT [] +synonym: "methylgallate biosynthesis" EXACT [] +synonym: "methylgallate formation" EXACT [] +synonym: "methylgallate synthesis" EXACT [] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0019489 ! methylgallate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046278 +name: 3,4-dihydroxybenzoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid)." [GOC:ai, PMID:24359411] +synonym: "protocatechuate metabolic process" EXACT [PMID:25072253] +synonym: "protocatechuate metabolism" EXACT [] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0046279 +name: 3,4-dihydroxybenzoate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate." [GOC:ai] +synonym: "protocatechuate anabolism" EXACT [] +synonym: "protocatechuate biosynthesis" EXACT [] +synonym: "protocatechuate biosynthetic process" EXACT [PMID:25072253] +synonym: "protocatechuate formation" EXACT [] +synonym: "protocatechuate synthesis" EXACT [] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0046278 ! 3,4-dihydroxybenzoate metabolic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046280 +name: chalcone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives." [GOC:ai] +synonym: "chalcone breakdown" EXACT [] +synonym: "chalcone catabolism" EXACT [] +synonym: "chalcone degradation" EXACT [] +is_a: GO:0009714 ! chalcone metabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process + +[Term] +id: GO:0046281 +name: cinnamic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid." [GOC:ai] +synonym: "cinnamic acid breakdown" EXACT [] +synonym: "cinnamic acid catabolism" EXACT [] +synonym: "cinnamic acid degradation" EXACT [] +synonym: "cinnamylic acid catabolic process" EXACT [] +synonym: "cinnamylic acid catabolism" EXACT [] +synonym: "phenylacrylic acid catabolic process" EXACT [] +synonym: "phenylacrylic acid catabolism" EXACT [] +is_a: GO:0009803 ! cinnamic acid metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046282 +name: cinnamic acid ester catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid." [GOC:ai] +synonym: "cinnamic acid ester breakdown" EXACT [] +synonym: "cinnamic acid ester catabolism" EXACT [] +synonym: "cinnamic acid ester degradation" EXACT [] +is_a: GO:0009801 ! cinnamic acid ester metabolic process +is_a: GO:0046271 ! phenylpropanoid catabolic process + +[Term] +id: GO:0046283 +name: anthocyanin-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers." [ISBN:0198506732] +synonym: "anthocyanin metabolic process" EXACT [] +synonym: "anthocyanin metabolism" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0046284 +name: anthocyanin-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins." [GOC:ai] +synonym: "anthocyanin breakdown" EXACT [] +synonym: "anthocyanin catabolic process" EXACT [] +synonym: "anthocyanin catabolism" EXACT [] +synonym: "anthocyanin degradation" EXACT [] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0046149 ! pigment catabolic process +is_a: GO:0046275 ! flavonoid catabolic process +is_a: GO:0046283 ! anthocyanin-containing compound metabolic process + +[Term] +id: GO:0046285 +name: flavonoid phytoalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection." [ISBN:0198506732] +synonym: "flavonoid phytoalexin metabolism" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0046286 +name: flavonoid phytoalexin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection." [GOC:ai] +synonym: "flavonoid phytoalexin breakdown" EXACT [] +synonym: "flavonoid phytoalexin catabolism" EXACT [] +synonym: "flavonoid phytoalexin degradation" EXACT [] +is_a: GO:0046275 ! flavonoid catabolic process +is_a: GO:0046285 ! flavonoid phytoalexin metabolic process +is_a: GO:0052316 ! phytoalexin catabolic process + +[Term] +id: GO:0046287 +name: isoflavonoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group." [GOC:ai, PMID:15734910] +synonym: "isoflavonoid metabolism" EXACT [] +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0046288 +name: isoflavonoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids." [GOC:ai] +synonym: "isoflavonoid breakdown" EXACT [] +synonym: "isoflavonoid catabolism" EXACT [] +synonym: "isoflavonoid degradation" EXACT [] +is_a: GO:0046271 ! phenylpropanoid catabolic process +is_a: GO:0046287 ! isoflavonoid metabolic process +is_a: GO:0046700 ! heterocycle catabolic process + +[Term] +id: GO:0046289 +name: isoflavonoid phytoalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection." [GOC:ai] +synonym: "isoflavonoid phytoalexin metabolism" EXACT [] +is_a: GO:0046287 ! isoflavonoid metabolic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0046290 +name: isoflavonoid phytoalexin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection." [GOC:ai] +synonym: "isoflavonoid phytoalexin breakdown" EXACT [] +synonym: "isoflavonoid phytoalexin catabolism" EXACT [] +synonym: "isoflavonoid phytoalexin degradation" EXACT [] +is_a: GO:0046288 ! isoflavonoid catabolic process +is_a: GO:0046289 ! isoflavonoid phytoalexin metabolic process +is_a: GO:0052316 ! phytoalexin catabolic process + +[Term] +id: GO:0046291 +name: obsolete 6-hydroxycineole biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2." [GOC:ai] +comment: This term was made obsolete because 6-hydroxycineole is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "6-endo-hydroxycineole biosynthesis" EXACT [] +synonym: "6-endo-hydroxycineole biosynthetic process" EXACT [] +synonym: "6-hydroxycineole anabolism" EXACT [] +synonym: "6-hydroxycineole biosynthesis" EXACT [] +synonym: "6-hydroxycineole biosynthetic process" EXACT [] +synonym: "6-hydroxycineole formation" EXACT [] +synonym: "6-hydroxycineole synthesis" EXACT [] +synonym: "hydroxycineol biosynthesis" EXACT [] +synonym: "hydroxycineol biosynthetic process" EXACT [] +is_obsolete: true +replaced_by: GO:0019638 + +[Term] +id: GO:0046292 +name: formaldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent." [GOC:ai] +synonym: "formaldehyde metabolism" EXACT [] +synonym: "methanal metabolic process" EXACT [] +synonym: "methanal metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0046293 +name: formaldehyde biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde." [GOC:ai] +synonym: "formaldehyde anabolism" EXACT [] +synonym: "formaldehyde biosynthesis" EXACT [] +synonym: "formaldehyde formation" EXACT [] +synonym: "formaldehyde synthesis" EXACT [] +synonym: "methanal biosynthesis" EXACT [] +synonym: "methanal biosynthetic process" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:0046292 ! formaldehyde metabolic process + +[Term] +id: GO:0046294 +name: formaldehyde catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde." [GOC:ai] +synonym: "formaldehyde breakdown" EXACT [] +synonym: "formaldehyde catabolism" EXACT [] +synonym: "formaldehyde degradation" EXACT [] +synonym: "methanal catabolic process" EXACT [] +synonym: "methanal catabolism" EXACT [] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:0046292 ! formaldehyde metabolic process +is_a: GO:0110095 ! cellular detoxification of aldehyde + +[Term] +id: GO:0046295 +name: glycolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid)." [GOC:ai] +synonym: "glycolate anabolism" EXACT [] +synonym: "glycolate biosynthesis" EXACT [] +synonym: "glycolate formation" EXACT [] +synonym: "glycolate synthesis" EXACT [] +is_a: GO:0009441 ! glycolate metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046296 +name: glycolate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid)." [GOC:ai] +synonym: "glycolate breakdown" EXACT [] +synonym: "glycolate catabolism" EXACT [] +synonym: "glycolate degradation" EXACT [] +is_a: GO:0009441 ! glycolate metabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046297 +name: obsolete 2,4-dichlorobenzoate biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)." [GOC:ai] +comment: This term was made obsolete because 2,4-dichlorobenzoate is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "2,4-dichlorobenzoate anabolism" EXACT [] +synonym: "2,4-dichlorobenzoate biosynthesis" EXACT [] +synonym: "2,4-dichlorobenzoate biosynthetic process" EXACT [] +synonym: "2,4-dichlorobenzoate formation" EXACT [] +synonym: "2,4-dichlorobenzoate synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018898 + +[Term] +id: GO:0046298 +name: 2,4-dichlorobenzoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)." [GOC:ai] +synonym: "2,4-dichlorobenzoate breakdown" EXACT [] +synonym: "2,4-dichlorobenzoate catabolism" EXACT [] +synonym: "2,4-dichlorobenzoate degradation" EXACT [] +is_a: GO:0018898 ! 2,4-dichlorobenzoate metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0046299 +name: obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [GOC:ai] +comment: This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "2,4-dichlorophenoxyacetic acid anabolism" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid biosynthesis" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid biosynthetic process" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid formation" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018901 + +[Term] +id: GO:0046300 +name: 2,4-dichlorophenoxyacetic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [GOC:ai] +synonym: "2,4-dichlorophenoxyacetic acid breakdown" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid catabolism" EXACT [] +synonym: "2,4-dichlorophenoxyacetic acid degradation" EXACT [] +is_a: GO:0009852 ! auxin catabolic process +is_a: GO:0018901 ! 2,4-dichlorophenoxyacetic acid metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process + +[Term] +id: GO:0046301 +name: obsolete 2-chloro-N-isopropylacetanilide biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants." [GOC:ai] +comment: This term was made obsolete because 2-chloro-N-isopropylacetanilide is not synthesized by living organisms and GO does not cover non-biological processes. +synonym: "2-chloro-N-isopropylacetanilide anabolism" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide biosynthesis" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide biosynthetic process" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide formation" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018889 + +[Term] +id: GO:0046302 +name: 2-chloro-N-isopropylacetanilide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants." [GOC:ai] +synonym: "2-chloro-N-isopropylacetanilide breakdown" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide catabolism" EXACT [] +synonym: "2-chloro-N-isopropylacetanilide degradation" EXACT [] +is_a: GO:0018889 ! 2-chloro-N-isopropylacetanilide metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0046303 +name: obsolete 2-nitropropane biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor." [GOC:ai] +comment: This term was made obsolete because 2-nitropropane is not synthesized by living organisms, and GO does not cover non-biological processes. +synonym: "2-nitropropane anabolism" EXACT [] +synonym: "2-nitropropane biosynthesis" EXACT [] +synonym: "2-nitropropane biosynthetic process" EXACT [] +synonym: "2-nitropropane formation" EXACT [] +synonym: "2-nitropropane synthesis" EXACT [] +is_obsolete: true +replaced_by: GO:0018938 + +[Term] +id: GO:0046304 +name: 2-nitropropane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor." [GOC:ai] +synonym: "2-nitropropane breakdown" EXACT [] +synonym: "2-nitropropane catabolism" EXACT [] +synonym: "2-nitropropane degradation" EXACT [] +is_a: GO:0018938 ! 2-nitropropane metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046305 +name: alkanesulfonate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group." [GOC:ai] +synonym: "alkanesulfonate anabolism" EXACT [] +synonym: "alkanesulfonate biosynthesis" EXACT [] +synonym: "alkanesulfonate formation" EXACT [] +synonym: "alkanesulfonate synthesis" EXACT [] +synonym: "alkanesulphonate biosynthesis" EXACT [] +synonym: "alkanesulphonate biosynthetic process" EXACT [] +is_a: GO:0016053 ! organic acid biosynthetic process +is_a: GO:0019694 ! alkanesulfonate metabolic process +is_a: GO:0044272 ! sulfur compound biosynthetic process + +[Term] +id: GO:0046306 +name: alkanesulfonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group." [GOC:ai] +synonym: "alkanesulfonate breakdown" EXACT [] +synonym: "alkanesulfonate catabolism" EXACT [] +synonym: "alkanesulfonate degradation" EXACT [] +synonym: "alkanesulphonate catabolic process" EXACT [] +synonym: "alkanesulphonate catabolism" EXACT [] +is_a: GO:0016054 ! organic acid catabolic process +is_a: GO:0019694 ! alkanesulfonate metabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0046307 +name: Z-phenylacetaldoxime biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds." [GOC:ai] +synonym: "Z-phenylacetaldoxime anabolism" EXACT [] +synonym: "Z-phenylacetaldoxime biosynthesis" EXACT [] +synonym: "Z-phenylacetaldoxime formation" EXACT [] +synonym: "Z-phenylacetaldoxime synthesis" EXACT [] +is_a: GO:0018983 ! Z-phenylacetaldoxime metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0046308 +name: Z-phenylacetaldoxime catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds." [GOC:ai] +synonym: "Z-phenylacetaldoxime breakdown" EXACT [] +synonym: "Z-phenylacetaldoxime catabolism" EXACT [] +synonym: "Z-phenylacetaldoxime degradation" EXACT [] +is_a: GO:0018983 ! Z-phenylacetaldoxime metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046309 +name: 1,3-dichloro-2-propanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic." [GOC:ai] +synonym: "1,3-dichloro-2-propanol anabolism" EXACT [] +synonym: "1,3-dichloro-2-propanol biosynthesis" EXACT [] +synonym: "1,3-dichloro-2-propanol formation" EXACT [] +synonym: "1,3-dichloro-2-propanol synthesis" EXACT [] +is_a: GO:0018902 ! 1,3-dichloro-2-propanol metabolic process +is_a: GO:0044108 ! cellular alcohol biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0046310 +name: 1,3-dichloro-2-propanol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic." [GOC:ai] +synonym: "1,3-dichloro-2-propanol breakdown" EXACT [] +synonym: "1,3-dichloro-2-propanol catabolism" EXACT [] +synonym: "1,3-dichloro-2-propanol degradation" EXACT [] +is_a: GO:0018902 ! 1,3-dichloro-2-propanol metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0044109 ! cellular alcohol catabolic process + +[Term] +id: GO:0046311 +name: prenylcysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue." [GOC:ai] +synonym: "prenylcysteine anabolism" EXACT [] +synonym: "prenylcysteine biosynthesis" EXACT [] +synonym: "prenylcysteine formation" EXACT [] +synonym: "prenylcysteine synthesis" EXACT [] +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0030329 ! prenylcysteine metabolic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process + +[Term] +id: GO:0046312 +name: phosphoarginine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai] +synonym: "phosphoarginine anabolism" EXACT [] +synonym: "phosphoarginine biosynthesis" EXACT [] +synonym: "phosphoarginine formation" EXACT [] +synonym: "phosphoarginine synthesis" EXACT [] +is_a: GO:0006604 ! phosphoarginine metabolic process +is_a: GO:0042396 ! phosphagen biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0046313 +name: phosphoarginine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine." [GOC:ai] +synonym: "phosphoarginine breakdown" EXACT [] +synonym: "phosphoarginine catabolism" EXACT [] +synonym: "phosphoarginine degradation" EXACT [] +is_a: GO:0006604 ! phosphoarginine metabolic process +is_a: GO:0042397 ! phosphagen catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process + +[Term] +id: GO:0046314 +name: phosphocreatine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase." [GOC:ai] +synonym: "phosphocreatine anabolism" EXACT [] +synonym: "phosphocreatine biosynthesis" EXACT [] +synonym: "phosphocreatine formation" EXACT [] +synonym: "phosphocreatine synthesis" EXACT [] +is_a: GO:0006603 ! phosphocreatine metabolic process +is_a: GO:0042396 ! phosphagen biosynthetic process + +[Term] +id: GO:0046315 +name: phosphocreatine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase." [GOC:ai] +synonym: "phosphocreatine breakdown" EXACT [] +synonym: "phosphocreatine catabolism" EXACT [] +synonym: "phosphocreatine degradation" EXACT [] +is_a: GO:0006603 ! phosphocreatine metabolic process +is_a: GO:0042397 ! phosphagen catabolic process + +[Term] +id: GO:0046316 +name: gluconokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+)." [EC:2.7.1.12, RHEA:19433] +synonym: "ATP:D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.12] +synonym: "gluconate kinase activity" EXACT [EC:2.7.1.12] +synonym: "gluconokinase (phosphorylating)" EXACT [EC:2.7.1.12] +xref: EC:2.7.1.12 +xref: KEGG_REACTION:R01737 +xref: MetaCyc:GLUCONOKIN-RXN +xref: RHEA:19433 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0046317 +name: regulation of glucosylceramide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai, GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of glucosylceramide anabolism" EXACT [] +synonym: "regulation of glucosylceramide biosynthesis" EXACT [] +synonym: "regulation of glucosylceramide formation" EXACT [] +synonym: "regulation of glucosylceramide synthesis" EXACT [] +is_a: GO:2000303 ! regulation of ceramide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006679 ! glucosylceramide biosynthetic process +relationship: regulates GO:0006679 ! glucosylceramide biosynthetic process + +[Term] +id: GO:0046318 +name: negative regulation of glucosylceramide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai, GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "down regulation of glucosylceramide biosynthetic process" EXACT [] +synonym: "down-regulation of glucosylceramide biosynthetic process" EXACT [] +synonym: "downregulation of glucosylceramide biosynthetic process" EXACT [] +synonym: "inhibition of glucosylceramide biosynthetic process" NARROW [] +synonym: "negative regulation of glucosylceramide anabolism" EXACT [] +synonym: "negative regulation of glucosylceramide biosynthesis" EXACT [] +synonym: "negative regulation of glucosylceramide formation" EXACT [] +synonym: "negative regulation of glucosylceramide synthesis" EXACT [] +is_a: GO:0046317 ! regulation of glucosylceramide biosynthetic process +is_a: GO:1900060 ! negative regulation of ceramide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006679 ! glucosylceramide biosynthetic process +relationship: negatively_regulates GO:0006679 ! glucosylceramide biosynthetic process + +[Term] +id: GO:0046319 +name: positive regulation of glucosylceramide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai] +synonym: "activation of glucosylceramide biosynthetic process" NARROW [] +synonym: "positive regulation of glucosylceramide anabolism" EXACT [] +synonym: "positive regulation of glucosylceramide biosynthesis" EXACT [] +synonym: "positive regulation of glucosylceramide formation" EXACT [] +synonym: "positive regulation of glucosylceramide synthesis" EXACT [] +synonym: "stimulation of glucosylceramide biosynthetic process" NARROW [] +synonym: "up regulation of glucosylceramide biosynthetic process" EXACT [] +synonym: "up-regulation of glucosylceramide biosynthetic process" EXACT [] +synonym: "upregulation of glucosylceramide biosynthetic process" EXACT [] +is_a: GO:0046317 ! regulation of glucosylceramide biosynthetic process +is_a: GO:2000304 ! positive regulation of ceramide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006679 ! glucosylceramide biosynthetic process +relationship: positively_regulates GO:0006679 ! glucosylceramide biosynthetic process + +[Term] +id: GO:0046320 +name: regulation of fatty acid oxidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fatty acid oxidation." [GOC:ai] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019395 ! fatty acid oxidation +relationship: regulates GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0046321 +name: positive regulation of fatty acid oxidation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fatty acid oxidation." [GOC:ai] +synonym: "activation of fatty acid oxidation" NARROW [] +synonym: "stimulation of fatty acid oxidation" NARROW [] +synonym: "up regulation of fatty acid oxidation" EXACT [] +synonym: "up-regulation of fatty acid oxidation" EXACT [] +synonym: "upregulation of fatty acid oxidation" EXACT [] +is_a: GO:0045923 ! positive regulation of fatty acid metabolic process +is_a: GO:0046320 ! regulation of fatty acid oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019395 ! fatty acid oxidation +relationship: positively_regulates GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0046322 +name: negative regulation of fatty acid oxidation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation." [GOC:ai] +synonym: "down regulation of fatty acid oxidation" EXACT [] +synonym: "down-regulation of fatty acid oxidation" EXACT [] +synonym: "downregulation of fatty acid oxidation" EXACT [] +synonym: "inhibition of fatty acid oxidation" NARROW [] +is_a: GO:0045922 ! negative regulation of fatty acid metabolic process +is_a: GO:0046320 ! regulation of fatty acid oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019395 ! fatty acid oxidation +relationship: negatively_regulates GO:0019395 ! fatty acid oxidation + +[Term] +id: GO:0046323 +name: glucose import +namespace: biological_process +def: "The directed movement of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai] +synonym: "glucose uptake" EXACT [GOC:dph, GOC:tb] +xref: Wikipedia:Glucose_uptake +is_a: GO:1904659 ! glucose transmembrane transport + +[Term] +id: GO:0046324 +name: regulation of glucose import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai] +synonym: "regulation of glucose uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010827 ! regulation of glucose transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046323 ! glucose import +relationship: regulates GO:0046323 ! glucose import + +[Term] +id: GO:0046325 +name: negative regulation of glucose import +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai] +synonym: "down regulation of glucose import" EXACT [] +synonym: "down-regulation of glucose import" EXACT [] +synonym: "downregulation of glucose import" EXACT [] +synonym: "inhibition of glucose import" NARROW [] +synonym: "negative regulation of glucose uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010829 ! negative regulation of glucose transmembrane transport +is_a: GO:0046324 ! regulation of glucose import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046323 ! glucose import +relationship: negatively_regulates GO:0046323 ! glucose import + +[Term] +id: GO:0046326 +name: positive regulation of glucose import +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle." [GOC:ai, GOC:dph, GOC:tb] +synonym: "activation of glucose import" NARROW [] +synonym: "positive regulation of glucose uptake" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of glucose import" NARROW [] +synonym: "up regulation of glucose import" EXACT [] +synonym: "up-regulation of glucose import" EXACT [] +synonym: "upregulation of glucose import" EXACT [] +is_a: GO:0010828 ! positive regulation of glucose transmembrane transport +is_a: GO:0046324 ! regulation of glucose import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046323 ! glucose import +relationship: positively_regulates GO:0046323 ! glucose import + +[Term] +id: GO:0046327 +name: glycerol biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate." [GOC:ai] +synonym: "glycerol anabolism from pyruvate" EXACT [] +synonym: "glycerol formation from pyruvate" EXACT [] +synonym: "glycerol synthesis from pyruvate" EXACT [] +synonym: "glyceroneogenesis" EXACT [] +is_a: GO:0006090 ! pyruvate metabolic process +is_a: GO:0006114 ! glycerol biosynthetic process +relationship: part_of GO:0019432 ! triglyceride biosynthetic process + +[Term] +id: GO:0046328 +name: regulation of JNK cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] +synonym: "regulation of SAPK cascade" BROAD [] +is_a: GO:0032872 ! regulation of stress-activated MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007254 ! JNK cascade +relationship: regulates GO:0007254 ! JNK cascade + +[Term] +id: GO:0046329 +name: negative regulation of JNK cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] +synonym: "down regulation of JNK cascade" EXACT [] +synonym: "down-regulation of JNK cascade" EXACT [] +synonym: "downregulation of JNK cascade" EXACT [] +synonym: "inhibition of JNK cascade" NARROW [] +is_a: GO:0032873 ! negative regulation of stress-activated MAPK cascade +is_a: GO:0046328 ! regulation of JNK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007254 ! JNK cascade +relationship: negatively_regulates GO:0007254 ! JNK cascade + +[Term] +id: GO:0046330 +name: positive regulation of JNK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] +synonym: "activation of JNK cascade" NARROW [] +synonym: "stimulation of JNK cascade" NARROW [] +synonym: "up regulation of JNK cascade" EXACT [] +synonym: "up-regulation of JNK cascade" EXACT [] +synonym: "upregulation of JNK cascade" EXACT [] +is_a: GO:0032874 ! positive regulation of stress-activated MAPK cascade +is_a: GO:0046328 ! regulation of JNK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007254 ! JNK cascade +relationship: positively_regulates GO:0007254 ! JNK cascade + +[Term] +id: GO:0046331 +name: lateral inhibition +namespace: biological_process +def: "Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells." [GOC:bf, GOC:kmv] +is_a: GO:0045168 ! cell-cell signaling involved in cell fate commitment + +[Term] +id: GO:0046332 +name: SMAD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SMAD signaling protein." [GOC:ai] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0046333 +name: octopamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." [ISBN:0198506732] +synonym: "octopamine metabolism" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0042439 ! ethanolamine-containing compound metabolic process + +[Term] +id: GO:0046334 +name: octopamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." [ISBN:0198506732] +synonym: "octopamine breakdown" EXACT [] +synonym: "octopamine catabolism" EXACT [] +synonym: "octopamine degradation" EXACT [] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042135 ! neurotransmitter catabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0046333 ! octopamine metabolic process + +[Term] +id: GO:0046335 +name: ethanolamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)." [GOC:ai] +synonym: "ethanolamine anabolism" EXACT [] +synonym: "ethanolamine biosynthesis" EXACT [] +synonym: "ethanolamine formation" EXACT [] +synonym: "ethanolamine synthesis" EXACT [] +is_a: GO:0006580 ! ethanolamine metabolic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0042401 ! cellular biogenic amine biosynthetic process +is_a: GO:1901162 ! primary amino compound biosynthetic process + +[Term] +id: GO:0046336 +name: ethanolamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)." [GOC:ai] +synonym: "ethanolamine breakdown" EXACT [] +synonym: "ethanolamine catabolism" EXACT [] +synonym: "ethanolamine degradation" EXACT [] +is_a: GO:0006580 ! ethanolamine metabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0042402 ! cellular biogenic amine catabolic process +is_a: GO:1901161 ! primary amino compound catabolic process + +[Term] +id: GO:0046337 +name: phosphatidylethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes." [GOC:curators, ISBN:0198506732] +synonym: "phosphatidylethanolamine metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0046338 +name: phosphatidylethanolamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732] +synonym: "phosphatidylethanolamine breakdown" EXACT [] +synonym: "phosphatidylethanolamine catabolism" EXACT [] +synonym: "phosphatidylethanolamine degradation" EXACT [] +is_a: GO:0046337 ! phosphatidylethanolamine metabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process + +[Term] +id: GO:0046339 +name: diacylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group." [PMID:11481335] +synonym: "diacylglycerol metabolism" EXACT [] +synonym: "diglyceride metabolism" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process + +[Term] +id: GO:0046340 +name: diacylglycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group." [PMID:11717312] +synonym: "diacylglycerol breakdown" EXACT [] +synonym: "diacylglycerol catabolism" EXACT [] +synonym: "diacylglycerol degradation" EXACT [] +synonym: "diglyceride catabolism" EXACT [] +is_a: GO:0046339 ! diacylglycerol metabolic process +is_a: GO:0046464 ! acylglycerol catabolic process + +[Term] +id: GO:0046341 +name: CDP-diacylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis." [PMID:24533860] +synonym: "CDP-diacylglycerol metabolism" EXACT [] +is_a: GO:0006220 ! pyrimidine nucleotide metabolic process +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0046342 +name: CDP-diacylglycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate." [PMID:6147353] +synonym: "CDP-diacylglycerol breakdown" EXACT [] +synonym: "CDP-diacylglycerol catabolism" EXACT [] +synonym: "CDP-diacylglycerol degradation" EXACT [] +is_a: GO:0006244 ! pyrimidine nucleotide catabolic process +is_a: GO:0046341 ! CDP-diacylglycerol metabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process + +[Term] +id: GO:0046343 +name: streptomycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome." [PMID:2111804] +synonym: "streptomycin metabolism" EXACT [] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process + +[Term] +id: GO:0046344 +name: ecdysteroid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development." [GOC:ai] +synonym: "ecdysteroid breakdown" EXACT [] +synonym: "ecdysteroid catabolism" EXACT [] +synonym: "ecdysteroid degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0045455 ! ecdysteroid metabolic process + +[Term] +id: GO:0046345 +name: abscisic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid." [GOC:ai] +synonym: "abscisic acid breakdown" EXACT [] +synonym: "abscisic acid catabolism" EXACT [] +synonym: "abscisic acid degradation" EXACT [] +is_a: GO:0009687 ! abscisic acid metabolic process +is_a: GO:0016107 ! sesquiterpenoid catabolic process +is_a: GO:0043290 ! apocarotenoid catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046346 +name: mannosamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins." [GOC:curators] +synonym: "mannosamine breakdown" EXACT [] +synonym: "mannosamine catabolism" EXACT [] +synonym: "mannosamine degradation" EXACT [] +is_a: GO:0006050 ! mannosamine metabolic process +is_a: GO:0046348 ! amino sugar catabolic process + +[Term] +id: GO:0046347 +name: mannosamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins." [GOC:curators] +synonym: "mannosamine anabolism" EXACT [] +synonym: "mannosamine biosynthesis" EXACT [] +synonym: "mannosamine formation" EXACT [] +synonym: "mannosamine synthesis" EXACT [] +is_a: GO:0006050 ! mannosamine metabolic process +is_a: GO:0046349 ! amino sugar biosynthetic process + +[Term] +id: GO:0046348 +name: amino sugar catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] +synonym: "amino sugar breakdown" EXACT [] +synonym: "amino sugar catabolism" EXACT [] +synonym: "amino sugar degradation" EXACT [] +synonym: "aminosaccharide catabolic process" EXACT [] +synonym: "aminosaccharide catabolism" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0046349 +name: amino sugar biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators] +synonym: "amino sugar anabolism" EXACT [] +synonym: "amino sugar biosynthesis" EXACT [] +synonym: "amino sugar formation" EXACT [] +synonym: "amino sugar synthesis" EXACT [] +synonym: "aminosaccharide biosynthesis" EXACT [] +synonym: "aminosaccharide biosynthetic process" EXACT [] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0046350 +name: galactosaminoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose." [GOC:ai] +synonym: "galactosaminoglycan metabolism" EXACT [] +is_a: GO:0030203 ! glycosaminoglycan metabolic process + +[Term] +id: GO:0046351 +name: disaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units." [GOC:ai] +synonym: "disaccharide anabolism" EXACT [] +synonym: "disaccharide biosynthesis" EXACT [] +synonym: "disaccharide formation" EXACT [] +synonym: "disaccharide synthesis" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process +is_a: GO:0009312 ! oligosaccharide biosynthetic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process + +[Term] +id: GO:0046352 +name: disaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units." [GOC:ai] +synonym: "disaccharide breakdown" EXACT [] +synonym: "disaccharide catabolism" EXACT [] +synonym: "disaccharide degradation" EXACT [] +is_a: GO:0005984 ! disaccharide metabolic process +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process + +[Term] +id: GO:0046353 +name: aminoglycoside 3-N-acetyltransferase activity +namespace: molecular_function +alt_id: GO:0016991 +def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring." [GOC:cb] +synonym: "3'-aminoglycoside acetyltransferase activity" RELATED [EC:2.3.1.81] +synonym: "3-N-aminoglycoside acetyltransferase activity" EXACT [EC:2.3.1.81] +synonym: "acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity" EXACT [EC:2.3.1.81] +synonym: "acetyl-CoA:gentamicin-C N3'-acetyltransferase activity" NARROW [EC:2.3.1.60] +synonym: "aminoglycoside acetyltransferase AAC(3)-1" RELATED [EC:2.3.1.60] +synonym: "aminoglycoside acetyltransferase AAC(3)-I activity" RELATED [EC:2.3.1.60] +synonym: "gentamicin 3'-N-acetyltransferase activity" NARROW [] +synonym: "gentamicin acetyltransferase I activity" NARROW [EC:2.3.1.60] +synonym: "gentamicin-(3)-N-acetyltransferase activity" NARROW [EC:2.3.1.81] +synonym: "gentamycin 3'-N-acetyltransferase activity" EXACT [] +synonym: "gentamycin acetyltransferase I" RELATED [EC:2.3.1.60] +xref: EC:2.3.1.60 +xref: EC:2.3.1.81 +xref: MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN +xref: MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN +is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity + +[Term] +id: GO:0046354 +name: mannan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose." [ISBN:0198506732] +synonym: "mannan anabolism" EXACT [] +synonym: "mannan biosynthesis" EXACT [] +synonym: "mannan formation" EXACT [] +synonym: "mannan synthesis" EXACT [] +is_a: GO:0010412 ! mannan metabolic process +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process + +[Term] +id: GO:0046355 +name: mannan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose." [ISBN:0198506732] +synonym: "mannan breakdown" EXACT [] +synonym: "mannan catabolism" EXACT [] +synonym: "mannan degradation" EXACT [] +is_a: GO:0010412 ! mannan metabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0044347 ! cell wall polysaccharide catabolic process + +[Term] +id: GO:0046356 +name: acetyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated." [GOC:ai] +synonym: "acetyl-CoA breakdown" EXACT [] +synonym: "acetyl-CoA catabolism" EXACT [] +synonym: "acetyl-CoA degradation" EXACT [] +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process + +[Term] +id: GO:0046357 +name: galactarate biosynthetic process +namespace: biological_process +alt_id: GO:0042872 +def: "The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid." [GOC:pr, ISBN:0198506732] +synonym: "D-galactarate anabolism" RELATED [] +synonym: "D-galactarate biosynthesis" RELATED [] +synonym: "D-galactarate biosynthetic process" RELATED [] +synonym: "D-galactarate formation" RELATED [] +synonym: "D-galactarate synthesis" RELATED [] +synonym: "galactarate anabolism" EXACT [] +synonym: "galactarate biosynthesis" EXACT [] +synonym: "galactarate formation" EXACT [] +synonym: "galactarate synthesis" EXACT [] +is_a: GO:0019578 ! aldaric acid biosynthetic process +is_a: GO:0019580 ! galactarate metabolic process + +[Term] +id: GO:0046358 +name: butyrate biosynthetic process +namespace: biological_process +alt_id: GO:0043439 +def: "The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid." [ISBN:0198506732] +synonym: "butanoic acid anabolism" EXACT [] +synonym: "butanoic acid biosynthesis" EXACT [] +synonym: "butanoic acid biosynthetic process" EXACT [] +synonym: "butanoic acid formation" EXACT [] +synonym: "butanoic acid synthesis" EXACT [] +synonym: "butyrate anabolism" EXACT [] +synonym: "butyrate biosynthesis" EXACT [] +synonym: "butyrate formation" EXACT [] +synonym: "butyrate synthesis" EXACT [] +is_a: GO:0019605 ! butyrate metabolic process +is_a: GO:0051790 ! short-chain fatty acid biosynthetic process + +[Term] +id: GO:0046359 +name: butyrate catabolic process +namespace: biological_process +alt_id: GO:0043440 +def: "The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid." [ISBN:0198506732] +synonym: "butanoic acid breakdown" EXACT [] +synonym: "butanoic acid catabolic process" EXACT [] +synonym: "butanoic acid catabolism" EXACT [] +synonym: "butanoic acid degradation" EXACT [] +synonym: "butyrate breakdown" EXACT [] +synonym: "butyrate catabolism" EXACT [] +synonym: "butyrate degradation" EXACT [] +is_a: GO:0019605 ! butyrate metabolic process +is_a: GO:0019626 ! short-chain fatty acid catabolic process + +[Term] +id: GO:0046360 +name: 2-oxobutyrate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2." [ISBN:0198506732] +synonym: "2-oxobutyrate anabolism" EXACT [] +synonym: "2-oxobutyrate biosynthesis" EXACT [] +synonym: "2-oxobutyrate formation" EXACT [] +synonym: "2-oxobutyrate synthesis" EXACT [] +synonym: "alpha-ketobutyrate biosynthesis" EXACT [] +synonym: "alpha-ketobutyrate biosynthetic process" EXACT [] +is_a: GO:0046361 ! 2-oxobutyrate metabolic process +is_a: GO:0051790 ! short-chain fatty acid biosynthetic process + +[Term] +id: GO:0046361 +name: 2-oxobutyrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2." [PMID:17034760] +synonym: "2-oxobutyrate metabolism" EXACT [] +synonym: "alpha-ketobutyrate metabolic process" EXACT [] +synonym: "alpha-ketobutyrate metabolism" EXACT [] +is_a: GO:0046459 ! short-chain fatty acid metabolic process + +[Term] +id: GO:0046362 +name: ribitol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose." [ISBN:0198506732] +synonym: "ribitol anabolism" EXACT [] +synonym: "ribitol biosynthesis" EXACT [] +synonym: "ribitol formation" EXACT [] +synonym: "ribitol synthesis" EXACT [] +is_a: GO:0019349 ! ribitol metabolic process +is_a: GO:0019526 ! pentitol biosynthetic process + +[Term] +id: GO:0046363 +name: ribitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose." [ISBN:0198506732] +synonym: "ribitol breakdown" EXACT [] +synonym: "ribitol catabolism" EXACT [] +synonym: "ribitol degradation" EXACT [] +is_a: GO:0019349 ! ribitol metabolic process +is_a: GO:0019527 ! pentitol catabolic process + +[Term] +id: GO:0046364 +name: monosaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] +synonym: "monosaccharide anabolism" EXACT [] +synonym: "monosaccharide biosynthesis" EXACT [] +synonym: "monosaccharide formation" EXACT [] +synonym: "monosaccharide synthesis" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0016051 ! carbohydrate biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process + +[Term] +id: GO:0046365 +name: monosaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] +synonym: "monosaccharide breakdown" EXACT [] +synonym: "monosaccharide catabolism" EXACT [] +synonym: "monosaccharide degradation" EXACT [] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0016052 ! carbohydrate catabolic process +is_a: GO:0044282 ! small molecule catabolic process + +[Term] +id: GO:0046366 +name: allose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [ISBN:0198506732] +synonym: "allose anabolism" EXACT [] +synonym: "allose biosynthesis" EXACT [] +synonym: "allose formation" EXACT [] +synonym: "allose synthesis" EXACT [] +is_a: GO:0019313 ! allose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0046367 +name: allose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [ISBN:0198506732] +synonym: "allose breakdown" EXACT [] +synonym: "allose catabolism" EXACT [] +synonym: "allose degradation" EXACT [] +is_a: GO:0019313 ! allose metabolic process +is_a: GO:0019320 ! hexose catabolic process + +[Term] +id: GO:0046368 +name: GDP-L-fucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-L-fucose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0046369 +name: galactose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose." [ISBN:0198506732] +synonym: "galactose anabolism" EXACT [] +synonym: "galactose biosynthesis" EXACT [] +synonym: "galactose formation" EXACT [] +synonym: "galactose synthesis" EXACT [] +is_a: GO:0006012 ! galactose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0046370 +name: fructose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose." [GOC:ai] +synonym: "fructose anabolism" EXACT [] +synonym: "fructose biosynthesis" EXACT [] +synonym: "fructose formation" EXACT [] +synonym: "fructose synthesis" EXACT [] +is_a: GO:0006000 ! fructose metabolic process +is_a: GO:0019319 ! hexose biosynthetic process + +[Term] +id: GO:0046371 +name: dTDP-mannose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate." [GOC:ai] +synonym: "dTDP-mannose metabolism" EXACT [] +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0046372 +name: D-arabinose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-arabinose metabolism" EXACT [] +is_a: GO:0019566 ! arabinose metabolic process + +[Term] +id: GO:0046373 +name: L-arabinose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-arabinose metabolism" EXACT [] +is_a: GO:0019566 ! arabinose metabolic process + +[Term] +id: GO:0046374 +name: teichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues." [ISBN:0198506732] +synonym: "teichoic acid metabolism" EXACT [] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0046375 +name: K antigen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens." [ISBN:0198506732] +synonym: "K antigen metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0046376 +name: GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate." [ISBN:0198506732] +synonym: "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism" EXACT [] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:0006721 ! terpenoid metabolic process + +[Term] +id: GO:0046377 +name: colanic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues." [GOC:ai, http://www.science.siu.edu/microbiology/micr425/425Notes/02-CellEnv.html] +synonym: "colanic acid metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0046378 +name: enterobacterial common antigen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria." [GOC:ma] +synonym: "enterobacterial common antigen metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0046379 +name: extracellular polysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polysaccharides used in extracellular structures." [GOC:ai] +synonym: "extracellular polysaccharide metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0046380 +name: N-acetylneuraminate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid." [ISBN:0198506732] +synonym: "N-acetylneuraminate anabolism" EXACT [] +synonym: "N-acetylneuraminate biosynthesis" EXACT [] +synonym: "N-acetylneuraminate formation" EXACT [] +synonym: "N-acetylneuraminate synthesis" EXACT [] +is_a: GO:0006054 ! N-acetylneuraminate metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046349 ! amino sugar biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process + +[Term] +id: GO:0046381 +name: CMP-N-acetylneuraminate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate." [GOC:ai] +synonym: "CMP-N-acetylneuraminate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0046382 +name: GDP-D-rhamnose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "GDP-D-rhamnose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0046383 +name: dTDP-rhamnose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate." [GOC:ai] +synonym: "dTDP-rhamnose metabolism" EXACT [] +is_a: GO:0009225 ! nucleotide-sugar metabolic process + +[Term] +id: GO:0046384 +name: 2-deoxyribose 1-phosphate metabolic process +namespace: biological_process +alt_id: GO:0046388 +def: "The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose." [ISBN:0198506732] +synonym: "2-deoxyribose 1-phosphate metabolism" EXACT [] +synonym: "deoxyribose 1-phosphate metabolic process" EXACT [] +synonym: "deoxyribose 1-phosphate metabolism" EXACT [] +is_a: GO:0019692 ! deoxyribose phosphate metabolic process + +[Term] +id: GO:0046385 +name: deoxyribose phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose." [ISBN:0198506732] +synonym: "deoxyribose phosphate anabolism" EXACT [] +synonym: "deoxyribose phosphate biosynthesis" EXACT [] +synonym: "deoxyribose phosphate formation" EXACT [] +synonym: "deoxyribose phosphate synthesis" EXACT [] +is_a: GO:0019692 ! deoxyribose phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0046386 +name: deoxyribose phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose." [ISBN:0198506732] +synonym: "deoxyribose phosphate breakdown" EXACT [] +synonym: "deoxyribose phosphate catabolism" EXACT [] +synonym: "deoxyribose phosphate degradation" EXACT [] +is_a: GO:0019692 ! deoxyribose phosphate metabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0046387 +name: deoxyribose 1,5-bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose." [GOC:ai] +synonym: "deoxyribose 1,5-bisphosphate metabolism" EXACT [] +is_a: GO:0019692 ! deoxyribose phosphate metabolic process + +[Term] +id: GO:0046389 +name: deoxyribose 5-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose." [GOC:ai] +synonym: "deoxyribose 5-phosphate metabolism" EXACT [] +is_a: GO:0019692 ! deoxyribose phosphate metabolic process + +[Term] +id: GO:0046390 +name: ribose phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar." [GOC:ai] +synonym: "ribose phosphate anabolism" EXACT [] +synonym: "ribose phosphate biosynthesis" EXACT [] +synonym: "ribose phosphate formation" EXACT [] +synonym: "ribose phosphate synthesis" EXACT [] +is_a: GO:0019693 ! ribose phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0046391 +name: 5-phosphoribose 1-diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate." [GOC:ai] +synonym: "5-phosphoribose 1-diphosphate metabolism" EXACT [] +synonym: "PRPP metabolic process" EXACT [] +xref: MetaCyc:PRPP-PWY +is_a: GO:0019693 ! ribose phosphate metabolic process + +[Term] +id: GO:0046392 +name: galactarate catabolic process +namespace: biological_process +alt_id: GO:0019582 +def: "The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid." [GOC:ai, GOC:pr] +synonym: "D-galactarate breakdown" RELATED [] +synonym: "D-galactarate catabolic process" RELATED [] +synonym: "D-galactarate catabolism" RELATED [] +synonym: "D-galactarate degradation" RELATED [] +synonym: "galactarate breakdown" EXACT [] +synonym: "galactarate catabolism" EXACT [] +synonym: "galactarate degradation" EXACT [] +xref: MetaCyc:GALACTARDEG-PWY +is_a: GO:0019579 ! aldaric acid catabolic process +is_a: GO:0019580 ! galactarate metabolic process + +[Term] +id: GO:0046394 +name: carboxylic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] +synonym: "carboxylic acid anabolism" EXACT [] +synonym: "carboxylic acid biosynthesis" EXACT [] +synonym: "carboxylic acid formation" EXACT [] +synonym: "carboxylic acid synthesis" EXACT [] +is_a: GO:0016053 ! organic acid biosynthetic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046395 +name: carboxylic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] +synonym: "carboxylic acid breakdown" EXACT [] +synonym: "carboxylic acid catabolism" EXACT [] +synonym: "carboxylic acid degradation" EXACT [] +is_a: GO:0016054 ! organic acid catabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046396 +name: D-galacturonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls." [GOC:ai, GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "D-galacturonate metabolism" EXACT [] +is_a: GO:0019586 ! galacturonate metabolic process + +[Term] +id: GO:0046397 +name: galacturonate catabolic process +namespace: biological_process +alt_id: GO:0019587 +def: "The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid." [GOC:ai] +synonym: "galacturonate breakdown" EXACT [] +synonym: "galacturonate catabolism" EXACT [] +synonym: "galacturonate degradation" EXACT [] +is_a: GO:0019586 ! galacturonate metabolic process +is_a: GO:0046365 ! monosaccharide catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process + +[Term] +id: GO:0046398 +name: UDP-glucuronate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate." [GOC:ai] +synonym: "UDP-glucuronate metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046399 +name: glucuronate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid." [GOC:ai] +synonym: "glucuronate anabolism" EXACT [] +synonym: "glucuronate biosynthesis" EXACT [] +synonym: "glucuronate formation" EXACT [] +synonym: "glucuronate synthesis" EXACT [] +is_a: GO:0019585 ! glucuronate metabolic process +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process + +[Term] +id: GO:0046400 +name: keto-3-deoxy-D-manno-octulosonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria." [GOC:ai, ISBN:0198506732] +synonym: "KDO metabolic process" EXACT [GOC:mah] +synonym: "KDO metabolism" EXACT [GOC:mah] +synonym: "keto-3-deoxy-D-manno-octulosonic acid metabolism" EXACT [] +synonym: "ketodeoxyoctanoate metabolic process" RELATED [ISBN:0198506732] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046401 +name: lipopolysaccharide core region metabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains." [ISBN:0198506732] +synonym: "lipopolysaccharide core region metabolism" EXACT [] +synonym: "LPS core region metabolic process" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +relationship: part_of GO:0008653 ! lipopolysaccharide metabolic process + +[Term] +id: GO:0046402 +name: O antigen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide." [ISBN:0198506732] +synonym: "O antigen metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0046403 +name: polynucleotide 3'-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage." [EC:3.1.3.32] +synonym: "2'(3')-polynucleotidase activity" EXACT [EC:3.1.3.32] +synonym: "5'-polynucleotidekinase 3'-phosphatase activity" EXACT [EC:3.1.3.32] +synonym: "deoxyribonucleate 3'-phosphatase activity" EXACT [EC:3.1.3.32] +synonym: "DNA 3'-phosphatase activity" EXACT [EC:3.1.3.32] +synonym: "polynucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.3.32] +xref: EC:3.1.3.32 +xref: MetaCyc:POLYNUCLEOTIDE-3-PHOSPHATASE-RXN +xref: Reactome:R-HSA-5649705 "PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB)" +is_a: GO:0098518 ! polynucleotide phosphatase activity +relationship: part_of GO:0098506 ! polynucleotide 3' dephosphorylation + +[Term] +id: GO:0046404 +name: ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA." [EC:2.7.1.78] +synonym: "ATP-dependent DNA 5'-hydroxyl-kinase activity" EXACT [] +synonym: "ATP-dependent DNA kinase activity" EXACT [] +synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] +synonym: "ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity" EXACT [] +xref: EC:2.7.1.78 +xref: KEGG_REACTION:R03840 +xref: MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN +is_a: GO:0051733 ! polydeoxyribonucleotide kinase activity +is_a: GO:0051734 ! ATP-dependent polynucleotide kinase activity + +[Term] +id: GO:0046405 +name: glycerol dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O." [EC:4.2.1.30, PMID:18307109] +synonym: "glycerol dehydrase activity" EXACT [EC:4.2.1.30] +synonym: "glycerol hydro-lyase (3-hydroxypropanal-forming)" EXACT [EC:4.2.1.30] +synonym: "glycerol hydro-lyase activity" EXACT [EC:4.2.1.30] +xref: EC:4.2.1.30 +xref: MetaCyc:GLYCEROL-DEHYDRATASE-RXN +xref: RHEA:19765 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0046406 +name: magnesium protoporphyrin IX methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester." [EC:2.1.1.11, RHEA:17809] +synonym: "(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "magnesium-protoporphyrin O-methyltransferase activity" EXACT [] +synonym: "Mg-protoporphyrin IX methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] +synonym: "S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] +xref: EC:2.1.1.11 +xref: KEGG_REACTION:R04237 +xref: MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN +xref: RHEA:17809 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0046408 +name: chlorophyll synthetase activity +namespace: molecular_function +alt_id: GO:0043787 +def: "Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate." [EC:2.5.1.62, RHEA:17317] +synonym: "chlorophyll synthase activity" EXACT [] +synonym: "chlorophyllide-a:phytyl-diphosphate phytyltransferase activity" EXACT [] +xref: EC:2.5.1.62 +xref: KEGG_REACTION:R06284 +xref: MetaCyc:RXN1F-66 +xref: RHEA:17317 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0046409 +name: p-coumarate 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+." [PMID:11429408, PMID:11891223] +synonym: "cytochrome P450 CYP98A3" NARROW [] +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0046410 +name: obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2." [EC:2.5.1.64, PMID:1459959] +comment: This term was made obsolete because it was derived from an EC entry (EC:2.5.1.64) that has since been split into two entries. +synonym: "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity" EXACT [] +is_obsolete: true +consider: GO:0070204 +consider: GO:0070205 + +[Term] +id: GO:0046411 +name: 2-keto-3-deoxygluconate transmembrane transport +namespace: biological_process +def: "The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:go_curators] +synonym: "2-keto-3-deoxygluconate transport" RELATED [] +is_a: GO:0015749 ! monosaccharide transmembrane transport +is_a: GO:0042873 ! aldonate transmembrane transport + +[Term] +id: GO:0046412 +name: phenylmercury acetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group." [GOC:ai] +synonym: "phenylmercury acetate metabolism" EXACT [] +is_a: GO:0018941 ! organomercury metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0046413 +name: organomercury catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom." [GOC:ai] +synonym: "organomercury breakdown" EXACT [] +synonym: "organomercury catabolism" EXACT [] +synonym: "organomercury degradation" EXACT [] +is_a: GO:0018941 ! organomercury metabolic process +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046414 +name: organomercury biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom." [GOC:ai] +synonym: "organomercury anabolism" EXACT [] +synonym: "organomercury biosynthesis" EXACT [] +synonym: "organomercury formation" EXACT [] +synonym: "organomercury synthesis" EXACT [] +is_a: GO:0018941 ! organomercury metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901576 ! organic substance biosynthetic process + +[Term] +id: GO:0046415 +name: urate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals." [ISBN:0198506732] +synonym: "urate metabolism" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0046416 +name: D-amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids." [GOC:ai, GOC:jsg] +synonym: "D-amino acid metabolism" EXACT [] +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0046417 +name: chorismate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid." [ISBN:0198506732] +synonym: "chorismate metabolism" EXACT [] +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0046418 +name: nopaline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative." [GOC:ai] +synonym: "nopaline metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0046419 +name: octopine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine." [GOC:ai] +synonym: "octopine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0046421 +name: methylisocitrate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate." [EC:4.1.3.30, RHEA:16809] +synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)" EXACT [EC:4.1.3.30] +synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity" EXACT [EC:4.1.3.30] +synonym: "2-methylisocitrate lyase activity" EXACT [] +synonym: "MICL" RELATED [EC:4.1.3.30] +xref: EC:4.1.3.30 +xref: KEGG_REACTION:R00409 +xref: MetaCyc:METHYLISOCITRATE-LYASE-RXN +xref: RHEA:16809 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0046422 +name: violaxanthin de-epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O." [EC:1.23.5.1, GOC:ai, ISBN:0471331309] +synonym: "VDE" RELATED [EC:1.23.5.1] +synonym: "violaxanthin:ascorbate oxidoreductase activity" EXACT [EC:1.23.5.1] +xref: EC:1.23.5.1 +xref: RHEA:32371 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0046423 +name: allene-oxide cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate." [EC:5.3.99.6, RHEA:22592] +synonym: "(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing)" EXACT [EC:5.3.99.6] +xref: EC:5.3.99.6 +xref: KEGG_REACTION:R03402 +xref: MetaCyc:ALLENE-OXIDE-CYCLASE-RXN +xref: RHEA:22592 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0046424 +name: ferulate 5-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+." [PMID:8692910, PMID:9880351] +xref: MetaCyc:RXN-1121 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0046425 +name: regulation of receptor signaling pathway via JAK-STAT +namespace: biological_process +alt_id: GO:0007262 +alt_id: GO:2000364 +def: "Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT." [GOC:bf] +synonym: "regulation of STAT protein import into nucleus" NARROW [] +synonym: "regulation of STAT protein nuclear translocation" NARROW [GOC:obol] +synonym: "STAT protein import into nucleus" NARROW [] +is_a: GO:1904892 ! regulation of receptor signaling pathway via STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007259 ! receptor signaling pathway via JAK-STAT +relationship: regulates GO:0007259 ! receptor signaling pathway via JAK-STAT +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13686 xsd:anyURI + +[Term] +id: GO:0046426 +name: negative regulation of receptor signaling pathway via JAK-STAT +namespace: biological_process +alt_id: GO:2000365 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT." [GOC:bf] +synonym: "down regulation of JAK-STAT cascade" EXACT [] +synonym: "down-regulation of JAK-STAT cascade" EXACT [] +synonym: "downregulation of JAK-STAT cascade" EXACT [] +synonym: "inhibition of JAK-STAT cascade" NARROW [] +synonym: "negative regulation of STAT protein import into nucleus" NARROW [] +synonym: "negative regulation of STAT protein nuclear translocation" NARROW [GOC:obol] +is_a: GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT +is_a: GO:1904893 ! negative regulation of receptor signaling pathway via STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007259 ! receptor signaling pathway via JAK-STAT +relationship: negatively_regulates GO:0007259 ! receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0046427 +name: positive regulation of receptor signaling pathway via JAK-STAT +namespace: biological_process +alt_id: GO:2000366 +def: "Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity." [GOC:bf] +synonym: "activation of JAK-STAT cascade" NARROW [] +synonym: "positive regulation of STAT protein import into nucleus" NARROW [] +synonym: "positive regulation of STAT protein nuclear translocation" NARROW [GOC:obol] +synonym: "stimulation of JAK-STAT cascade" NARROW [] +synonym: "up regulation of JAK-STAT cascade" EXACT [] +synonym: "up-regulation of JAK-STAT cascade" EXACT [] +synonym: "upregulation of JAK-STAT cascade" EXACT [] +is_a: GO:0046425 ! regulation of receptor signaling pathway via JAK-STAT +is_a: GO:1904894 ! positive regulation of receptor signaling pathway via STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007259 ! receptor signaling pathway via JAK-STAT +relationship: positively_regulates GO:0007259 ! receptor signaling pathway via JAK-STAT + +[Term] +id: GO:0046428 +name: 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2." [MetaCyc:DMK-RXN] +synonym: "1,4-Dihydroxy-2-naphtoate prenyltransferase activity" EXACT [] +xref: EC:2.5.1 +xref: MetaCyc:DMK-RXN +is_a: GO:0002094 ! polyprenyltransferase activity + +[Term] +id: GO:0046429 +name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin." [EC:1.17.7.1, PMID:11752431] +synonym: "(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity" EXACT systematic_synonym [EC:1.17.7.1] +synonym: "(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity" EXACT [EC:1.17.7.1] +synonym: "1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity" EXACT [MetaCyc:HYDROXY-METHYL-BUTENYL-DIP] +synonym: "1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity" EXACT [MetaCyc:HYDROXY-METHYL-BUTENYL-DIP] +xref: EC:1.17.7.1 +xref: KEGG_REACTION:R08689 +xref: MetaCyc:RXN0-882 +is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor + +[Term] +id: GO:0046430 +name: non-phosphorylated glucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving non-phosphorylated forms of glucose." [GOC:ai] +synonym: "non-phosphorylated glucose metabolism" EXACT [] +is_a: GO:0006006 ! glucose metabolic process + +[Term] +id: GO:0046431 +name: (R)-4-hydroxymandelate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate)." [GOC:ai, ISBN:0198506732] +synonym: "(R)-4-hydroxymandelate metabolism" EXACT [] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0046432 +name: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A." [GOC:ai] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process + +[Term] +id: GO:0046433 +name: 2-aminoethylphosphonate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms." [GOC:ai, PMID:12107130] +synonym: "2-aminoethylphosphonate metabolism" EXACT [] +synonym: "2-phosphonoethylamine metabolic process" EXACT [] +synonym: "2-phosphonoethylamine metabolism" EXACT [] +synonym: "ciliatine metabolic process" EXACT [] +synonym: "ciliatine metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:1901160 ! primary amino compound metabolic process + +[Term] +id: GO:0046434 +name: organophosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound." [GOC:ai] +synonym: "organophosphate breakdown" EXACT [] +synonym: "organophosphate catabolism" EXACT [] +synonym: "organophosphate degradation" EXACT [] +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046435 +name: 3-(3-hydroxy)phenylpropionate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate." [GOC:ai] +synonym: "3-(3-hydroxy)phenylpropionate metabolism" EXACT [] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0046436 +name: D-alanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid." [GOC:ai, GOC:jsg] +synonym: "D-alanine metabolism" EXACT [] +is_a: GO:0046144 ! D-alanine family amino acid metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0046437 +name: D-amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids." [GOC:ai, GOC:jsg] +synonym: "D-amino acid anabolism" EXACT [] +synonym: "D-amino acid biosynthesis" EXACT [] +synonym: "D-amino acid formation" EXACT [] +synonym: "D-amino acid synthesis" EXACT [] +is_a: GO:0046416 ! D-amino acid metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process + +[Term] +id: GO:0046438 +name: D-cysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin." [GOC:ai] +synonym: "D-cysteine metabolism" EXACT [] +is_a: GO:0006534 ! cysteine metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0046439 +name: L-cysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-cysteine metabolism" EXACT [] +is_a: GO:0006534 ! cysteine metabolic process + +[Term] +id: GO:0046440 +name: L-lysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-lysine metabolism" EXACT [] +is_a: GO:0006553 ! lysine metabolic process +is_a: GO:0017144 ! drug metabolic process + +[Term] +id: GO:0046441 +name: D-lysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "D-lysine metabolism" EXACT [] +is_a: GO:0006553 ! lysine metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0046442 +name: aerobactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid." [GOC:ai] +synonym: "aerobactin metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process + +[Term] +id: GO:0046443 +name: FAD metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide." [PMID:20822113] +synonym: "FAD metabolism" EXACT [] +synonym: "oxidized flavin adenine dinucleotide metabolic process" EXACT [] +synonym: "oxidized flavin adenine dinucleotide metabolism" EXACT [] +synonym: "oxidized flavin-adenine dinucleotide metabolic process" EXACT [] +synonym: "oxidized flavin-adenine dinucleotide metabolism" EXACT [] +is_a: GO:0072387 ! flavin adenine dinucleotide metabolic process + +[Term] +id: GO:0046444 +name: FMN metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase." [GOC:ai, PMID:20822113] +synonym: "FMN metabolism" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0009161 ! ribonucleoside monophosphate metabolic process +is_a: GO:0009259 ! ribonucleotide metabolic process +is_a: GO:0042726 ! flavin-containing compound metabolic process + +[Term] +id: GO:0046445 +name: benzyl isoquinoline alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings." [GOC:ai, ISBN:0198506732] +synonym: "benzyl isoquinoline alkaloid metabolism" EXACT [] +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process + +[Term] +id: GO:0046446 +name: purine alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure." [GOC:ai] +synonym: "purine alkaloid metabolism" EXACT [] +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process + +[Term] +id: GO:0046447 +name: terpenoid indole alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)." [GOC:ai, http://rycomusa.com/aspp2000/public/P29/0525.html] +synonym: "terpenoid indole alkaloid metabolism" EXACT [] +is_a: GO:0035834 ! indole alkaloid metabolic process + +[Term] +id: GO:0046448 +name: tropane alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system." [GOC:ai, ISBN:0198506732] +synonym: "tropane alkaloid metabolism" EXACT [] +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0046449 +name: creatinine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine." [ISBN:0198506732] +synonym: "creatinine metabolism" EXACT [] +is_a: GO:0072338 ! cellular lactam metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0046450 +name: dethiobiotin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms." [ISBN:0198506732] +synonym: "desthiobiotin metabolic process" EXACT [] +synonym: "desthiobiotin metabolism" EXACT [] +synonym: "dethiobiotin metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0046451 +name: diaminopimelate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls." [GOC:ai, ISBN:0198506732] +synonym: "diaminopimelate metabolism" EXACT [] +is_a: GO:0006520 ! cellular amino acid metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0046452 +name: dihydrofolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate." [ISBN:0198506732] +synonym: "dihydrofolate metabolism" EXACT [] +synonym: "dihydrofolate reduction" NARROW [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0046453 +name: dipyrrin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group." [http://www.chem.qmw.ac.uk/iupac/class/tetpy.html#03] +synonym: "dipyrrin metabolism" EXACT [] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0046454 +name: dimethylsilanediol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products." [GOC:ai] +synonym: "dimethylsilanediol metabolism" EXACT [] +is_a: GO:0018945 ! organosilicon metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0046455 +name: organosilicon catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon." [GOC:ai] +synonym: "organosilicon breakdown" EXACT [] +synonym: "organosilicon catabolism" EXACT [] +synonym: "organosilicon degradation" EXACT [] +synonym: "organosilicone catabolic process" EXACT [] +synonym: "organosilicone catabolism" EXACT [] +is_a: GO:0018945 ! organosilicon metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0046456 +name: icosanoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids." [ISBN:0198506732] +synonym: "eicosanoid biosynthesis" EXACT [] +synonym: "eicosanoid biosynthetic process" EXACT [] +synonym: "icosanoid anabolism" EXACT [] +synonym: "icosanoid biosynthesis" EXACT [] +synonym: "icosanoid formation" EXACT [] +synonym: "icosanoid synthesis" EXACT [] +xref: Wikipedia:Eicosanoid +is_a: GO:0006690 ! icosanoid metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1901570 ! fatty acid derivative biosynthetic process + +[Term] +id: GO:0046457 +name: prostanoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure." [GOC:ai] +synonym: "prostanoid anabolism" EXACT [] +synonym: "prostanoid biosynthesis" EXACT [] +synonym: "prostanoid formation" EXACT [] +synonym: "prostanoid synthesis" EXACT [] +xref: Wikipedia:Prostanoid#Biosynthesis +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0006692 ! prostanoid metabolic process +is_a: GO:0046456 ! icosanoid biosynthetic process + +[Term] +id: GO:0046458 +name: hexadecanal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde." [PMID:25047030] +synonym: "hexadecanal metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process + +[Term] +id: GO:0046459 +name: short-chain fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fatty acids with a chain length of less than C6." [Wikipedia:Fatty_acid_metabolism] +synonym: "short-chain fatty acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0046460 +name: neutral lipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity." [GOC:ai] +synonym: "neutral lipid anabolism" EXACT [] +synonym: "neutral lipid biosynthesis" EXACT [] +synonym: "neutral lipid formation" EXACT [] +synonym: "neutral lipid synthesis" EXACT [] +is_a: GO:0006638 ! neutral lipid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0046461 +name: neutral lipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity." [GOC:ai] +synonym: "neutral lipid breakdown" EXACT [] +synonym: "neutral lipid catabolism" EXACT [] +synonym: "neutral lipid degradation" EXACT [] +is_a: GO:0006638 ! neutral lipid metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process + +[Term] +id: GO:0046462 +name: monoacylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified." [ISBN:0198506732] +synonym: "monoacylglycerol metabolism" EXACT [] +synonym: "monoglyceride metabolic process" EXACT [] +synonym: "monoglyceride metabolism" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process + +[Term] +id: GO:0046463 +name: acylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids." [GOC:ai] +synonym: "acylglycerol anabolism" EXACT [] +synonym: "acylglycerol biosynthesis" EXACT [] +synonym: "acylglycerol formation" EXACT [] +synonym: "acylglycerol synthesis" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process +is_a: GO:0045017 ! glycerolipid biosynthetic process +is_a: GO:0046460 ! neutral lipid biosynthetic process + +[Term] +id: GO:0046464 +name: acylglycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids." [GOC:ai] +synonym: "acylglycerol breakdown" EXACT [] +synonym: "acylglycerol catabolism" EXACT [] +synonym: "acylglycerol degradation" EXACT [] +is_a: GO:0006639 ! acylglycerol metabolic process +is_a: GO:0046461 ! neutral lipid catabolic process +is_a: GO:0046503 ! glycerolipid catabolic process + +[Term] +id: GO:0046465 +name: dolichyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes." [ISBN:0198506732] +synonym: "dolichyl diphosphate metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process + +[Term] +id: GO:0046466 +name: membrane lipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] +synonym: "membrane lipid breakdown" EXACT [] +synonym: "membrane lipid catabolism" EXACT [] +synonym: "membrane lipid degradation" EXACT [] +synonym: "membrane lipid peroxidation" BROAD [GOC:tb] +is_a: GO:0006643 ! membrane lipid metabolic process +is_a: GO:0044242 ! cellular lipid catabolic process + +[Term] +id: GO:0046467 +name: membrane lipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane." [GOC:ai] +synonym: "membrane lipid anabolism" EXACT [] +synonym: "membrane lipid biosynthesis" EXACT [] +synonym: "membrane lipid formation" EXACT [] +synonym: "membrane lipid synthesis" EXACT [] +is_a: GO:0006643 ! membrane lipid metabolic process +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044249 ! cellular biosynthetic process + +[Term] +id: GO:0046468 +name: phosphatidyl-N-monomethylethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria." [http://www.lipid.co.uk] +synonym: "phosphatidyl-N-monomethylethanolamine metabolism" EXACT [] +synonym: "PMME metabolic process" EXACT [] +synonym: "PMME metabolism" EXACT [] +is_a: GO:0046337 ! phosphatidylethanolamine metabolic process + +[Term] +id: GO:0046469 +name: platelet activating factor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli." [ISBN:0198547684] +synonym: "PAF metabolic process" EXACT [] +synonym: "PAF metabolism" EXACT [] +synonym: "platelet activating factor metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0046470 +name: phosphatidylcholine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes." [ISBN:0198506732] +synonym: "phosphatidylcholine metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0046471 +name: phosphatidylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes." [ISBN:0198506732] +synonym: "phosphatidylglycerol metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0046473 +name: phosphatidic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids." [ISBN:0198506732] +synonym: "phosphatidic acid metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0046474 +name: glycerophospholipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue." [ISBN:0198506732] +synonym: "glycerophospholipid anabolism" EXACT [] +synonym: "glycerophospholipid biosynthesis" EXACT [] +synonym: "glycerophospholipid formation" EXACT [] +synonym: "glycerophospholipid synthesis" EXACT [] +synonym: "phosphoglyceride biosynthesis" EXACT [] +synonym: "phosphoglyceride biosynthetic process" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0045017 ! glycerolipid biosynthetic process + +[Term] +id: GO:0046475 +name: glycerophospholipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue." [ISBN:0198506732] +synonym: "glycerophospholipid breakdown" EXACT [] +synonym: "glycerophospholipid catabolism" EXACT [] +synonym: "glycerophospholipid degradation" EXACT [] +synonym: "phosphoglyceride catabolic process" EXACT [] +synonym: "phosphoglyceride catabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0046503 ! glycerolipid catabolic process + +[Term] +id: GO:0046476 +name: glycosylceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group." [GOC:ai] +synonym: "glycosylceramide anabolism" EXACT [] +synonym: "glycosylceramide biosynthesis" EXACT [] +synonym: "glycosylceramide formation" EXACT [] +synonym: "glycosylceramide synthesis" EXACT [] +is_a: GO:0006677 ! glycosylceramide metabolic process +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +is_a: GO:0046513 ! ceramide biosynthetic process + +[Term] +id: GO:0046477 +name: glycosylceramide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group." [GOC:ai] +synonym: "glycosylceramide breakdown" EXACT [] +synonym: "glycosylceramide catabolism" EXACT [] +synonym: "glycosylceramide degradation" EXACT [] +is_a: GO:0006677 ! glycosylceramide metabolic process +is_a: GO:0046479 ! glycosphingolipid catabolic process +is_a: GO:0046514 ! ceramide catabolic process + +[Term] +id: GO:0046478 +name: lactosylceramide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides." [ISBN:0198506732] +synonym: "lactosylceramide metabolism" EXACT [] +is_a: GO:0006672 ! ceramide metabolic process +is_a: GO:0006687 ! glycosphingolipid metabolic process + +[Term] +id: GO:0046479 +name: glycosphingolipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide." [ISBN:0198506732] +synonym: "glycosphingolipid breakdown" EXACT [] +synonym: "glycosphingolipid catabolism" EXACT [] +synonym: "glycosphingolipid degradation" EXACT [] +is_a: GO:0006687 ! glycosphingolipid metabolic process +is_a: GO:0019377 ! glycolipid catabolic process +is_a: GO:0030149 ! sphingolipid catabolic process + +[Term] +id: GO:0046480 +name: galactolipid galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol." [EC:2.4.1.184] +synonym: "3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.184] +synonym: "DGDG synthase activity" BROAD [EC:2.4.1.184] +synonym: "digalactosyldiacylglycerol synthase activity" BROAD [EC:2.4.1.184] +synonym: "galactolipid-galactolipid galactosyltransferase activity" EXACT [EC:2.4.1.184] +synonym: "galactolipid:galactolipid galactosyltransferase activity" EXACT [] +synonym: "GGGT activity" EXACT [EC:2.4.1.184] +synonym: "interlipid galactosyltransferase activity" RELATED [EC:2.4.1.184] +xref: EC:2.4.1.184 +xref: MetaCyc:RXN-1226 +xref: RHEA:15921 +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0046481 +name: digalactosyldiacylglycerol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP." [EC:2.4.1.241, RHEA:10520] +synonym: "DGD1" NARROW [] +synonym: "DGD2" NARROW [] +synonym: "DGDG synthase activity" BROAD [EC:2.4.1.241] +synonym: "UDP-galactose-dependent DGDG synthase activity" EXACT [EC:2.4.1.241] +synonym: "UDP-galactose-dependent digalactosyldiacylglycerol synthase activity" EXACT [EC:2.4.1.241] +synonym: "UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.241] +synonym: "UDP-galactose:MGDG galactosyltransferase activity" EXACT [] +xref: EC:2.4.1.241 +xref: KEGG_REACTION:R04469 +xref: MetaCyc:RXN-1225 +xref: RHEA:10520 +xref: Wikipedia:Digalactosyldiacylglycerol_synthase +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0046482 +name: para-aminobenzoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins." [ISBN:0198506732, PMID:11377864, PMID:11960743] +synonym: "4-aminobenzoic acid metabolic process" EXACT [] +synonym: "4-aminobenzoic acid metabolism" EXACT [] +synonym: "p-aminobenzoic acid metabolic process" EXACT [] +synonym: "p-aminobenzoic acid metabolism" EXACT [] +synonym: "PABA metabolic process" EXACT [] +synonym: "PABA metabolism" EXACT [] +synonym: "para-aminobenzoic acid metabolism" EXACT [] +synonym: "vitamin Bx metabolic process" EXACT [] +synonym: "vitamin Bx metabolism" EXACT [] +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process + +[Term] +id: GO:0046483 +name: heterocycle metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198506732] +subset: goslim_pir +synonym: "heterocycle metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0046484 +name: oxazole or thiazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position." [GOC:curators] +synonym: "oxazole or thiazole metabolism" EXACT [] +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0046485 +name: ether lipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol." [ISBN:0198506732, PMID:15337120] +synonym: "ether lipid metabolism" EXACT [] +synonym: "plasmalogen metabolic process" NARROW [] +xref: Wikipedia:Ether_lipid +is_a: GO:0006662 ! glycerol ether metabolic process +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0046486 +name: glycerolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis." [GOC:ai, PMID:8906569] +synonym: "glycerolipid metabolism" EXACT [] +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0046487 +name: glyoxylate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH." [ISBN:0198506732] +synonym: "glyoxylate metabolism" EXACT [] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0046488 +name: phosphatidylinositol metabolic process +namespace: biological_process +alt_id: GO:0030384 +def: "The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [ISBN:0198506732] +synonym: "phosphatidylinositol metabolism" EXACT [] +synonym: "phosphoinositide metabolic process" EXACT [] +synonym: "phosphoinositide metabolism" EXACT [] +synonym: "PtdIns metabolic process" EXACT [] +synonym: "PtdIns metabolism" EXACT [] +is_a: GO:0006650 ! glycerophospholipid metabolic process + +[Term] +id: GO:0046490 +name: isopentenyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids." [ISBN:0198506732] +subset: goslim_pir +synonym: "IPP metabolic process" EXACT [] +synonym: "IPP metabolism" EXACT [] +synonym: "isopentenyl diphosphate metabolism" EXACT [] +synonym: "isopentenyl pyrophosphate metabolic process" EXACT [] +synonym: "isopentenyl pyrophosphate metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process + +[Term] +id: GO:0046491 +name: L-methylmalonyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals." [GOC:jsg, GOC:mah, ISBN:0198506732] +synonym: "L-methylmalonyl-CoA metabolism" EXACT [] +is_a: GO:0006637 ! acyl-CoA metabolic process + +[Term] +id: GO:0046492 +name: heme B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes." [GOC:yaf, PMID:29414780] +synonym: "haem B metabolic process" EXACT [] +synonym: "haem B metabolism" EXACT [] +synonym: "heme B metabolism" EXACT [] +synonym: "protoheme metabolic process" EXACT [] +synonym: "protoheme metabolism" EXACT [] +is_a: GO:0042168 ! heme metabolic process + +[Term] +id: GO:0046493 +name: lipid A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common." [ISBN:0198506732, PMID:20974832, PMID:22216004] +synonym: "lipid A metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:1901269 ! lipooligosaccharide metabolic process + +[Term] +id: GO:0046494 +name: rhizobactin 1021 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti." [MetaCyc:PWY-761, PMID:11274118] +synonym: "rhizobactin 1021 metabolism" EXACT [] +is_a: GO:0009237 ! siderophore metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process + +[Term] +id: GO:0046495 +name: nicotinamide riboside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide." [ISBN:0198506732] +synonym: "N-ribosylnicotinamide metabolic process" EXACT [] +synonym: "nicotinamide riboside metabolism" EXACT [] +is_a: GO:0070637 ! pyridine nucleoside metabolic process + +[Term] +id: GO:0046496 +name: nicotinamide nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide." [ISBN:0198506732] +synonym: "nicotinamide nucleotide metabolism" EXACT [] +is_a: GO:0019362 ! pyridine nucleotide metabolic process + +[Term] +id: GO:0046497 +name: nicotinate nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin)." [ISBN:0198506732] +synonym: "nicotinate nucleotide metabolism" EXACT [] +is_a: GO:0019362 ! pyridine nucleotide metabolic process + +[Term] +id: GO:0046498 +name: S-adenosylhomocysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine." [ISBN:0198506732] +synonym: "S-adenosylhomocysteine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0046499 +name: S-adenosylmethioninamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt." [GOC:mah, MetaCyc:S-ADENOSYLMETHIONINAMINE] +synonym: "S-adenosylmethioninamine metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0046128 ! purine ribonucleoside metabolic process + +[Term] +id: GO:0046500 +name: S-adenosylmethionine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism." [GOC:go_curators, ISBN:0198506732] +synonym: "S-adenosyl methionine metabolic process" EXACT [] +synonym: "S-adenosyl methionine metabolism" EXACT [] +synonym: "S-adenosylmethionine metabolism" EXACT [] +synonym: "SAM metabolic process" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0071704 ! organic substance metabolic process + +[Term] +id: GO:0046501 +name: protoporphyrinogen IX metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation." [ISBN:0198506732] +comment: See also the molecular function term 'ferrochelatase activity ; GO:0004325'. +synonym: "protoporphyrinogen IX metabolism" EXACT [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process + +[Term] +id: GO:0046502 +name: uroporphyrinogen III metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds." [GOC:ai] +synonym: "uroporphyrinogen III metabolism" EXACT [] +is_a: GO:0006778 ! porphyrin-containing compound metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046503 +name: glycerolipid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone." [GOC:ai] +synonym: "glycerolipid breakdown" EXACT [] +synonym: "glycerolipid catabolism" EXACT [] +synonym: "glycerolipid degradation" EXACT [] +is_a: GO:0044242 ! cellular lipid catabolic process +is_a: GO:0046486 ! glycerolipid metabolic process + +[Term] +id: GO:0046504 +name: glycerol ether biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol." [GOC:ai] +synonym: "glycerol ether anabolism" EXACT [] +synonym: "glycerol ether biosynthesis" EXACT [] +synonym: "glycerol ether formation" EXACT [] +synonym: "glycerol ether synthesis" EXACT [] +is_a: GO:0006662 ! glycerol ether metabolic process +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process + +[Term] +id: GO:0046505 +name: sulfolipid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid." [PMID:9751667] +synonym: "sulfolipid metabolism" EXACT [] +synonym: "sulpholipid metabolic process" EXACT [] +synonym: "sulpholipid metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +is_a: GO:0044255 ! cellular lipid metabolic process + +[Term] +id: GO:0046506 +name: sulfolipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid." [PMID:9751667] +synonym: "sulfolipid anabolism" EXACT [] +synonym: "sulfolipid biosynthesis" EXACT [] +synonym: "sulfolipid formation" EXACT [] +synonym: "sulfolipid synthesis" EXACT [] +synonym: "sulpholipid biosynthesis" EXACT [] +synonym: "sulpholipid biosynthetic process" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0046505 ! sulfolipid metabolic process + +[Term] +id: GO:0046507 +name: UDPsulfoquinovose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose." [EC:3.13.1.1, RHEA:13197] +synonym: "sulfite:UDP-glucose sulfotransferase activity" EXACT [] +synonym: "UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity" EXACT [EC:3.13.1.1] +synonym: "UDP-sulfoquinovose synthase activity" EXACT [EC:3.13.1.1] +synonym: "UDPsulphoquinovose synthase activity" EXACT [] +xref: EC:3.13.1.1 +xref: KEGG_REACTION:R05775 +xref: MetaCyc:RXN-1223 +xref: RHEA:13197 +is_a: GO:0046508 ! hydrolase activity, acting on carbon-sulfur bonds + +[Term] +id: GO:0046508 +name: hydrolase activity, acting on carbon-sulfur bonds +namespace: molecular_function +def: "Catalysis of the hydrolysis of any carbon-sulfur bond, C-S." [GOC:jl] +synonym: "hydrolase activity, acting on carbon-sulphur bonds" EXACT [] +xref: EC:3.13 +is_a: GO:0016787 ! hydrolase activity + +[Term] +id: GO:0046509 +name: 1,2-diacylglycerol 3-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP." [EC:2.4.1.46, RHEA:14945] +synonym: "1-beta-MGDG activity" EXACT [EC:2.4.1.46] +synonym: "1beta-MGDG" RELATED [EC:2.4.1.46] +synonym: "MGDG synthase activity" EXACT [] +synonym: "monogalactosyldiacylglycerol synthase activity" EXACT [] +synonym: "UDP galactose-1,2-diacylglycerol galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose-diacylglyceride galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.46] +synonym: "UDP-galactose:diacylglycerol galactosyltransferase activity" EXACT [] +synonym: "UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.46] +synonym: "uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity" EXACT [] +xref: EC:2.4.1.46 +xref: KEGG_REACTION:R02691 +xref: MetaCyc:2.4.1.46-RXN +xref: RHEA:14945 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0046510 +name: UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP." [MetaCyc:RXN-1224] +synonym: "sulfolipid synthase" BROAD [] +synonym: "UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity" EXACT [] +xref: MetaCyc:RXN-1224 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0046511 +name: sphinganine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol." [GOC:ai] +synonym: "dihydrosphingosine biosynthesis" EXACT [] +synonym: "dihydrosphingosine biosynthetic process" EXACT [] +synonym: "sphinganine anabolism" EXACT [] +synonym: "sphinganine biosynthesis" EXACT [] +synonym: "sphinganine formation" EXACT [] +synonym: "sphinganine synthesis" EXACT [] +is_a: GO:0006667 ! sphinganine metabolic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0046520 ! sphingoid biosynthetic process + +[Term] +id: GO:0046512 +name: sphingosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues." [GOC:ma, ISBN:0198506732] +synonym: "sphingosine anabolism" EXACT [] +synonym: "sphingosine biosynthesis" EXACT [] +synonym: "sphingosine formation" EXACT [] +synonym: "sphingosine synthesis" EXACT [] +is_a: GO:0006670 ! sphingosine metabolic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0046520 ! sphingoid biosynthetic process + +[Term] +id: GO:0046513 +name: ceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid." [GOC:ai] +synonym: "ceramide anabolism" EXACT [] +synonym: "ceramide biosynthesis" EXACT [] +synonym: "ceramide formation" EXACT [] +synonym: "ceramide synthesis" EXACT [] +is_a: GO:0006672 ! ceramide metabolic process +is_a: GO:0030148 ! sphingolipid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process + +[Term] +id: GO:0046514 +name: ceramide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid." [GOC:ai] +synonym: "ceramide breakdown" EXACT [] +synonym: "ceramide catabolism" EXACT [] +synonym: "ceramide degradation" EXACT [] +is_a: GO:0006672 ! ceramide metabolic process +is_a: GO:0030149 ! sphingolipid catabolic process + +[Term] +id: GO:0046516 +name: hypusine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine." [GOC:ai] +synonym: "hypusine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0046517 +name: octamethylcyclotetrasiloxane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom." [GOC:ai, PMID:10224038] +synonym: "octamethylcyclotetrasiloxane breakdown" EXACT [] +synonym: "octamethylcyclotetrasiloxane catabolism" EXACT [] +synonym: "octamethylcyclotetrasiloxane degradation" EXACT [] +is_a: GO:0046455 ! organosilicon catabolic process +is_a: GO:0046518 ! octamethylcyclotetrasiloxane metabolic process +is_a: GO:0046700 ! heterocycle catabolic process + +[Term] +id: GO:0046518 +name: octamethylcyclotetrasiloxane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom." [GOC:ai, http://chemfinder.cambridgesoft.com/] +synonym: "octamethylcyclotetrasiloxane metabolism" EXACT [] +is_a: GO:0018945 ! organosilicon metabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0046519 +name: sphingoid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds." [ISBN:0198506732] +synonym: "sphingoid base metabolic process" EXACT [] +synonym: "sphingoid base metabolism" EXACT [] +synonym: "sphingoid metabolism" EXACT [] +is_a: GO:0006665 ! sphingolipid metabolic process + +[Term] +id: GO:0046520 +name: sphingoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds." [ISBN:0198506732] +synonym: "sphingoid anabolism" EXACT [] +synonym: "sphingoid biosynthesis" EXACT [] +synonym: "sphingoid formation" EXACT [] +synonym: "sphingoid synthesis" EXACT [] +is_a: GO:0030148 ! sphingolipid biosynthetic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0046521 +name: sphingoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds." [ISBN:0198506732] +synonym: "sphingoid breakdown" EXACT [] +synonym: "sphingoid catabolism" EXACT [] +synonym: "sphingoid degradation" EXACT [] +is_a: GO:0030149 ! sphingolipid catabolic process +is_a: GO:0046519 ! sphingoid metabolic process + +[Term] +id: GO:0046522 +name: S-methyl-5-thioribose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.100, RHEA:22312] +synonym: "5-methylthioribose kinase (phosphorylating)" EXACT [EC:2.7.1.100] +synonym: "5-methylthioribose kinase activity" EXACT [] +synonym: "ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity" EXACT [EC:2.7.1.100] +synonym: "ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity" EXACT [EC:2.7.1.100] +synonym: "methylthioribose kinase activity" EXACT [EC:2.7.1.100] +synonym: "MTR kinase activity" EXACT [EC:2.7.1.100] +xref: EC:2.7.1.100 +xref: KEGG_REACTION:R04143 +xref: MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN +xref: RHEA:22312 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0046523 +name: S-methyl-5-thioribose-1-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate." [EC:5.3.1.23, RHEA:19989] +synonym: "1-phospho-5'-S-methylthioribose isomerase activity" EXACT [EC:5.3.1.23] +synonym: "1-PMTR isomerase activity" EXACT [EC:5.3.1.23] +synonym: "5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.23] +synonym: "5-methylthioribose-1-phosphate isomerase activity" EXACT [] +synonym: "methylthioribose 1-phosphate isomerase activity" EXACT [EC:5.3.1.23] +synonym: "MTR-1-P isomerase activity" EXACT [EC:5.3.1.23] +synonym: "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] +synonym: "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.23] +synonym: "S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] +synonym: "S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] +xref: EC:5.3.1.23 +xref: KEGG_REACTION:R04420 +xref: MetaCyc:5.3.1.23-RXN +xref: Reactome:R-HSA-1237096 "Methylthio-ribose-P = Methylthio-ribulose-P" +xref: Reactome:R-HSA-1299507 "Methylthio-ribulose-P = Methylthio-ribose-P" +xref: RHEA:19989 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0046524 +name: sucrose-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate." [EC:2.4.1.14] +synonym: "SPS" RELATED [EC:2.4.1.14] +synonym: "sucrose 6-phosphate synthase activity" EXACT [EC:2.4.1.14] +synonym: "sucrose phosphate synthetase activity" EXACT [EC:2.4.1.14] +synonym: "sucrose phosphate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "sucrosephosphate-UDP glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "UDP-glucose-fructose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "UDPglucose-fructose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.14] +synonym: "uridine diphosphoglucose-fructose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] +xref: EC:2.4.1.14 +xref: MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN +xref: RHEA:22172 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0046525 +name: xylosylprotein 4-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein." [EC:2.4.1.133] +synonym: "galactosyltransferase I activity" RELATED [EC:2.4.1.133] +synonym: "UDP-D-galactose:D-xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] +synonym: "UDP-D-galactose:xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] +synonym: "UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.133] +synonym: "UDP-galactose:xylose galactosyltransferase activity" EXACT [] +synonym: "UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.133] +synonym: "uridine diphosphogalactose-xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] +xref: EC:2.4.1.133 +xref: MetaCyc:2.4.1.133-RXN +xref: Reactome:R-HSA-1889981 "B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker" +xref: Reactome:R-HSA-3560804 "Defective B4GALT7 does not transfer Gal to xylosyl-unit of the tetrasaccharide linker" +is_a: GO:0035250 ! UDP-galactosyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0046526 +name: D-xylulose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH." [EC:1.1.1.9, RHEA:20433] +synonym: "xylitol dehydrogenase activity" EXACT [EC:1.1.1.9] +xref: EC:1.1.1.9 +xref: KEGG_REACTION:R01896 +xref: MetaCyc:D-XYLULOSE-REDUCTASE-RXN +xref: Reactome:R-HSA-5662471 "SORD tetramer oxidizes xylitol to D-xylulose" +xref: RHEA:20433 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +is_a: GO:0031320 ! hexitol dehydrogenase activity + +[Term] +id: GO:0046527 +name: glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [ISBN:0198506732] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0046528 +name: imaginal disc fusion +namespace: biological_process +def: "The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis." [PMID:11494317] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007560 ! imaginal disc morphogenesis + +[Term] +id: GO:0046529 +name: imaginal disc fusion, thorax closure +namespace: biological_process +def: "The joining of the parts of the wing imaginal discs, giving rise to the adult thorax." [http://sdb.bio.purdue.edu/fly/gene/fos4.htm] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0046528 ! imaginal disc fusion + +[Term] +id: GO:0046530 +name: photoreceptor cell differentiation +namespace: biological_process +alt_id: GO:0007467 +def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732] +is_a: GO:0030182 ! neuron differentiation + +[Term] +id: GO:0046532 +name: regulation of photoreceptor cell differentiation +namespace: biological_process +alt_id: GO:0045673 +def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] +synonym: "regulation of photoreceptor differentiation" EXACT [] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046530 ! photoreceptor cell differentiation +relationship: regulates GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0046533 +name: negative regulation of photoreceptor cell differentiation +namespace: biological_process +alt_id: GO:0045674 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] +synonym: "down regulation of photoreceptor cell differentiation" EXACT [] +synonym: "down regulation of photoreceptor differentiation" EXACT [] +synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] +synonym: "down-regulation of photoreceptor differentiation" EXACT [] +synonym: "downregulation of photoreceptor cell differentiation" EXACT [] +synonym: "downregulation of photoreceptor differentiation" EXACT [] +synonym: "inhibition of photoreceptor cell differentiation" NARROW [] +synonym: "inhibition of photoreceptor differentiation" NARROW [] +synonym: "negative regulation of photoreceptor differentiation" EXACT [] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046530 ! photoreceptor cell differentiation +relationship: negatively_regulates GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0046534 +name: positive regulation of photoreceptor cell differentiation +namespace: biological_process +alt_id: GO:0045675 +def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] +synonym: "activation of photoreceptor cell differentiation" NARROW [] +synonym: "activation of photoreceptor differentiation" NARROW [] +synonym: "positive regulation of photoreceptor differentiation" EXACT [] +synonym: "stimulation of photoreceptor cell differentiation" NARROW [] +synonym: "stimulation of photoreceptor differentiation" NARROW [] +synonym: "up regulation of photoreceptor cell differentiation" EXACT [] +synonym: "up regulation of photoreceptor differentiation" EXACT [] +synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] +synonym: "up-regulation of photoreceptor differentiation" EXACT [] +synonym: "upregulation of photoreceptor cell differentiation" EXACT [] +synonym: "upregulation of photoreceptor differentiation" EXACT [] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046530 ! photoreceptor cell differentiation +relationship: positively_regulates GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0046535 +name: detection of chemical stimulus involved in sensory perception of umami taste +namespace: biological_process +def: "The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates." [GOC:ai, GOC:dos, PMID:11894099] +synonym: "perception of umami taste, detection of chemical stimulus" EXACT [] +synonym: "perception of umami taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of umami taste" EXACT [] +synonym: "sensory detection of umami taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of umami taste" EXACT [] +synonym: "sensory transduction of umami taste" EXACT [] +synonym: "umami taste detection" EXACT [] +is_a: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050917 ! sensory perception of umami taste +relationship: part_of GO:0050917 ! sensory perception of umami taste + +[Term] +id: GO:0046536 +name: dosage compensation complex +namespace: cellular_component +def: "A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes." [GOC:kmv, GOC:mah] +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000803 ! sex chromosome +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0046537 +name: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate." [EC:5.4.2.1] +synonym: "PGAM-i" RELATED [EC:5.4.2.1] +is_a: GO:0004619 ! phosphoglycerate mutase activity + +[Term] +id: GO:0046538 +name: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate." [EC:5.4.2.1] +synonym: "glycerate phosphomutase (diphosphoglycerate cofactor) activity" EXACT [EC:5.4.2.1] +synonym: "PGAM-d" RELATED [EC:5.4.2.1] +is_a: GO:0004619 ! phosphoglycerate mutase activity + +[Term] +id: GO:0046539 +name: histamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+)." [EC:2.1.1.8, RHEA:19301] +synonym: "histamine 1-methyltransferase activity" EXACT [EC:2.1.1.8] +synonym: "histamine methyltransferase activity" EXACT [EC:2.1.1.8] +synonym: "histamine-methylating enzyme" RELATED [EC:2.1.1.8] +synonym: "imidazolemethyltransferase activity" EXACT [EC:2.1.1.8] +synonym: "S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity" EXACT [EC:2.1.1.8] +synonym: "S-adenosylmethionine-histamine N-methyltransferase activity" EXACT [EC:2.1.1.8] +xref: EC:2.1.1.8 +xref: KEGG_REACTION:R02155 +xref: MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN +xref: Reactome:R-HSA-175993 "HNMT transfers CH3 group from AdoMet to Hist" +xref: RHEA:19301 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0046540 +name: U4/U6 x U5 tri-snRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins." [GOC:krc, GOC:pr, PMID:11867543] +synonym: "U4/U6.U5 snRNP complex" EXACT [] +is_a: GO:0097526 ! spliceosomal tri-snRNP complex +relationship: has_part GO:0005682 ! U5 snRNP +relationship: has_part GO:0071001 ! U4/U6 snRNP + +[Term] +id: GO:0046541 +name: saliva secretion +namespace: biological_process +def: "The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin." [GOC:curators, UBERON:0001836] +synonym: "salivation" EXACT [] +xref: Wikipedia:Salivation +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0022600 ! digestive system process +is_a: GO:0032941 ! secretion by tissue + +[Term] +id: GO:0046542 +name: obsolete alpha-factor export +namespace: biological_process +def: "OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell." [GOC:ai] +comment: This term was made obsolete because it is a gene product based term and it does not involve a unique process. +synonym: "alpha-factor export" EXACT [] +is_obsolete: true +consider: GO:0015833 + +[Term] +id: GO:0046543 +name: development of secondary female sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion." [GOC:ai] +is_a: GO:0045136 ! development of secondary sexual characteristics + +[Term] +id: GO:0046544 +name: development of secondary male sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion." [GOC:ai] +is_a: GO:0045136 ! development of secondary sexual characteristics +relationship: part_of GO:0046661 ! male sex differentiation + +[Term] +id: GO:0046545 +name: development of primary female sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai] +is_a: GO:0045137 ! development of primary sexual characteristics +relationship: part_of GO:0046660 ! female sex differentiation + +[Term] +id: GO:0046546 +name: development of primary male sexual characteristics +namespace: biological_process +def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai] +is_a: GO:0045137 ! development of primary sexual characteristics +relationship: part_of GO:0046661 ! male sex differentiation + +[Term] +id: GO:0046547 +name: trans-aconitate 3-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine." [EC:2.1.1.145, RHEA:22200] +synonym: "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity" EXACT [EC:2.1.1.145] +xref: EC:2.1.1.145 +xref: KEGG_REACTION:R05764 +xref: MetaCyc:2.1.1.145-RXN +xref: RHEA:22200 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0046548 +name: retinal rod cell development +namespace: biological_process +def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732] +is_a: GO:0042462 ! eye photoreceptor cell development +relationship: part_of GO:0060221 ! retinal rod cell differentiation + +[Term] +id: GO:0046549 +name: retinal cone cell development +namespace: biological_process +def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732] +is_a: GO:0042462 ! eye photoreceptor cell development +relationship: part_of GO:0042670 ! retinal cone cell differentiation + +[Term] +id: GO:0046550 +name: (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine +namespace: biological_process +def: "The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7." [RESID:AA0328] +synonym: "(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine anabolism from asparagine" EXACT [] +synonym: "(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine formation from asparagine" EXACT [] +synonym: "(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine synthesis from asparagine" EXACT [] +xref: RESID:AA0328 +is_a: GO:0006528 ! asparagine metabolic process +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0018196 ! peptidyl-asparagine modification +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process + +[Term] +id: GO:0046551 +name: retinal cone cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:mtg_sensu, PMID:3076112, PMID:3937883] +is_a: GO:0060220 ! camera-type eye photoreceptor cell fate commitment +relationship: part_of GO:0042670 ! retinal cone cell differentiation + +[Term] +id: GO:0046552 +name: photoreceptor cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments." [GOC:mtg_sensu] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0046530 ! photoreceptor cell differentiation + +[Term] +id: GO:0046553 +name: D-malate dehydrogenase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate." [EC:1.1.1.83, RHEA:18365] +synonym: "(R)-malate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.83] +synonym: "bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating)" RELATED [EC:1.1.1.83] +synonym: "D-malate dehydrogenase activity" EXACT [EC:1.1.1.83] +synonym: "D-malic enzyme" RELATED [EC:1.1.1.83] +xref: EC:1.1.1.83 +xref: KEGG_REACTION:R00215 +xref: MetaCyc:1.1.1.83-RXN +xref: RHEA:18365 +is_a: GO:0016615 ! malate dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0046554 +name: malate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+." [EC:1.1.1.82] +synonym: "(S)-malate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.82, KEGG_REACTION:R00343] +synonym: "malate NADP dehydrogenase activity" EXACT [EC:1.1.1.82] +synonym: "malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.82] +synonym: "NADP malate dehydrogenase activity" EXACT [EC:1.1.1.82] +synonym: "NADP-linked malate dehydrogenase activity" EXACT [EC:1.1.1.82] +synonym: "NADP-malate dehydrogenase activity" EXACT [EC:1.1.1.82] +xref: EC:1.1.1.82 +xref: KEGG_REACTION:R00343 +xref: MetaCyc:MALATE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:10824 +is_a: GO:0016615 ! malate dehydrogenase activity +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0046555 +name: acetylxylan esterase activity +namespace: molecular_function +def: "Catalysis of the deacetylation of xylans and xylo-oligosaccharides." [EC:3.1.1.72] +xref: EC:3.1.1.72 +xref: MetaCyc:3.1.1.72-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0046556 +name: alpha-L-arabinofuranosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides." [EC:3.2.1.55, GOC:mf] +synonym: "alpha-arabinofuranosidase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-arabinosidase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-L-arabinanase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-L-arabinofuranoside arabinofuranohydrolase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-L-arabinofuranoside hydrolase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-L-arabinosidase activity" EXACT [EC:3.2.1.55] +synonym: "alpha-N-arabinofuranosidase activity" RELATED [] +synonym: "arabinofuranosidase activity" EXACT [EC:3.2.1.55] +synonym: "arabinosidase activity" EXACT [EC:3.2.1.55] +synonym: "L-arabinosidase activity" EXACT [EC:3.2.1.55] +synonym: "polysaccharide alpha-L-arabinofuranosidase activity" EXACT [] +xref: EC:3.2.1.55 +xref: MetaCyc:3.2.1.55-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0046557 +name: glucan endo-1,6-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans." [EC:3.2.1.75] +synonym: "1,6-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.75] +synonym: "beta-1,6-glucan 6-glucanohydrolase activity" EXACT [EC:3.2.1.75] +synonym: "beta-1,6-glucan hydrolase activity" EXACT [EC:3.2.1.75] +synonym: "beta-1,6-glucanase activity" EXACT [EC:3.2.1.75] +synonym: "beta-1,6-glucanase-pustulanase activity" EXACT [EC:3.2.1.75] +synonym: "beta-1->6-glucan hydrolase activity" EXACT [EC:3.2.1.75] +synonym: "endo-(1,6)-beta-D-glucanase activity" EXACT [] +synonym: "endo-(1->6)-beta-D-glucanase activity" EXACT [EC:3.2.1.75] +synonym: "endo-1,6-beta-D-glucanase activity" EXACT [EC:3.2.1.75] +synonym: "endo-1,6-beta-glucanase activity" EXACT [EC:3.2.1.75] +synonym: "endo-beta-1,6-glucanase activity" EXACT [EC:3.2.1.75] +xref: EC:3.2.1.75 +xref: MetaCyc:3.2.1.75-RXN +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0046558 +name: arabinan endo-1,5-alpha-L-arabinosidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans." [EC:3.2.1.99] +synonym: "1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity" EXACT [EC:3.2.1.99] +synonym: "endo-1,5-alpha-L-arabinanase activity" EXACT [EC:3.2.1.99] +synonym: "endo-alpha-1,5-arabanase activity" EXACT [EC:3.2.1.99] +synonym: "endo-arabanase activity" EXACT [EC:3.2.1.99] +xref: EC:3.2.1.99 +xref: MetaCyc:3.2.1.99-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0046559 +name: alpha-glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate." [EC:3.2.1.139] +synonym: "alpha-D-glucosiduronate glucuronohydrolase activity" EXACT [EC:3.2.1.139] +synonym: "alpha-glucosiduronase activity" EXACT [EC:3.2.1.139] +xref: EC:3.2.1.139 +xref: MetaCyc:3.2.1.139-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0046560 +name: obsolete scytalidopepsin B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin." [EC:3.4.23.32] +comment: This term was made obsolete because it represents a gene product. +synonym: "Ganoderma lucidum aspartic proteinase activity" EXACT [EC:3.4.23.32] +synonym: "Ganoderma lucidum carboxyl proteinase activity" EXACT [EC:3.4.23.32] +synonym: "Scytalidium aspartic proteinase B activity" RELATED [EC:3.4.23.32] +synonym: "Scytalidium lignicolum aspartic proteinase B" RELATED [EC:3.4.23.32] +synonym: "scytalidopepsin B activity" EXACT [] +synonym: "SLB" RELATED [EC:3.4.23.32] +xref: EC:3.4.23.32 +xref: MetaCyc:3.4.23.32-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0046561 +name: obsolete penicillopepsin activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen." [EC:3.4.23.20] +comment: This term was made obsolete because it represents a gene product. +synonym: "acid protease A" EXACT [] +synonym: "Penicillium aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium caseicolum aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium citrinum acid proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium citrinum aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium cyclopium acid proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium duponti aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium expansum acid proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium expansum aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium janthinellum acid proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium janthinellum aspartic protease activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium janthinellum aspartic proteinase activity" EXACT [EC:3.4.23.20] +synonym: "Penicillium roqueforti acid proteinase activity" EXACT [EC:3.4.23.20] +synonym: "penicillopepsin activity" EXACT [] +synonym: "peptidase A activity" BROAD [EC:3.4.23.20] +xref: EC:3.4.23.20 +xref: MetaCyc:3.4.23.20-RXN +is_obsolete: true +replaced_by: GO:0004190 + +[Term] +id: GO:0046562 +name: glucose oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2." [EC:1.1.3.4, GOC:mah] +synonym: "beta-D-glucose oxidase activity" EXACT [] +synonym: "beta-D-glucose:oxygen 1-oxido-reductase activity" EXACT [EC:1.1.3.4] +synonym: "beta-D-glucose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.4] +synonym: "beta-D-glucose:quinone oxidoreductase activity" EXACT [EC:1.1.3.4] +synonym: "corylophyline" RELATED [EC:1.1.3.4] +synonym: "D-glucose oxidase activity" EXACT [EC:1.1.3.4] +synonym: "D-glucose-1-oxidase activity" EXACT [EC:1.1.3.4] +synonym: "deoxin-1" RELATED [EC:1.1.3.4] +synonym: "glucose aerodehydrogenase activity" EXACT [EC:1.1.3.4] +synonym: "glucose oxyhydrase activity" EXACT [EC:1.1.3.4] +synonym: "GOD activity" RELATED [EC:1.1.3.4] +synonym: "microcid" RELATED [EC:1.1.3.4] +synonym: "penatin" RELATED [EC:1.1.3.4] +xref: EC:1.1.3.4 +xref: KEGG_REACTION:R01522 +xref: MetaCyc:GLUCOSE-OXIDASE-RXN +xref: RHEA:11428 +is_a: GO:0047979 ! hexose oxidase activity + +[Term] +id: GO:0046563 +name: methanol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde." [MetaCyc:METHANOL-OXIDASE-RXN] +comment: Note that EC:1.1.3.31 was deleted from EC as it cannot be distinguished from alcohol oxidase (EC:1.1.3.13). +xref: EC:1.1.3 +xref: MetaCyc:METHANOL-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0046564 +name: oxalate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + oxalate = CO(2) + formate." [EC:4.1.1.2, RHEA:16509] +synonym: "oxalate carboxy-lyase (formate-forming)" EXACT [EC:4.1.1.2] +synonym: "oxalate carboxy-lyase activity" EXACT [EC:4.1.1.2] +xref: EC:4.1.1.2 +xref: KEGG_REACTION:R00522 +xref: MetaCyc:OXALATE-DECARBOXYLASE-RXN +xref: RHEA:16509 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0046565 +name: 3-dehydroshikimate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate." [EC:4.2.1.118, MetaCyc:DHSHIKIMATE-DEHYDRO-RXN] +xref: EC:4.2.1.118 +xref: MetaCyc:DHSHIKIMATE-DEHYDRO-RXN +xref: RHEA:24848 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0046566 +name: DOPA dioxygenase activity +namespace: molecular_function +def: "Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid." [PMID:11711071] +synonym: "dihydroxyphenylalanine dioxygenase activity" EXACT [] +xref: MetaCyc:RXN-8460 +is_a: GO:0051213 ! dioxygenase activity + +[Term] +id: GO:0046567 +name: aphidicolan-16 beta-ol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate." [EC:4.2.3.42, PMID:12149019] +synonym: "9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming)" EXACT [EC:4.2.3.42] +xref: EC:4.2.3.42 +xref: KEGG_REACTION:R06313 +xref: MetaCyc:RXN-10631 +xref: RHEA:26213 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0046568 +name: 3-methylbutanol:NAD(P) oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde." [EC:1.1.1.265] +synonym: "3-methylbutanal reductase [NAD(P)] activity" EXACT [EC:1.1.1.265] +synonym: "3-methylbutyraldehyde reductase activity" EXACT [] +synonym: "isoamyl alcohol oxidase activity" EXACT [] +xref: EC:1.1.1.265 +xref: MetaCyc:1.1.1.265-RXN +is_a: GO:0018455 ! alcohol dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0046569 +name: glyoxal oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2." [PMID:11733005] +synonym: "GLOX" EXACT [] +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0046570 +name: methylthioribulose 1-phosphate dehydratase activity +namespace: molecular_function +alt_id: GO:0043809 +def: "Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O." [EC:4.2.1.109, RHEA:15549] +synonym: "1-PMT-ribulose dehydratase activity" EXACT [EC:4.2.1.109] +synonym: "5-methylthioribulose-1-phosphate 4-dehydratase activity" EXACT [MetaCyc:R145-RXN] +synonym: "methylthioribulose-1-phosphate dehydratase activity" EXACT [] +synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]" RELATED [EC:4.2.1.109] +synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity" EXACT [] +synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming]" EXACT [] +xref: EC:4.2.1.109 +xref: KEGG_REACTION:R07392 +xref: MetaCyc:R145-RXN +xref: Reactome:R-HSA-1237140 "Dehydration of methylthio-ribulose-P" +xref: RHEA:15549 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0046571 +name: aspartate-2-keto-4-methylthiobutyrate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate." [MetaCyc:R15-RXN] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0046572 +name: versicolorin B synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: versiconal = versicolorin B + H2O." [MetaCyc:RXN-9494, PMID:8784203] +xref: EC:4.2.1.143 +xref: MetaCyc:RXN-9494 +xref: RHEA:33859 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0046573 +name: lactonohydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group." [PMID:11640988] +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0046574 +name: glycuronidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid." [PMID:10441389, PMID:12044176] +synonym: "glucuronyl hydrolase activity" EXACT [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0046575 +name: rhamnogalacturonan acetylesterase activity +namespace: molecular_function +def: "Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan." [PMID:10801485] +is_a: GO:0008126 ! acetylesterase activity + +[Term] +id: GO:0046576 +name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue." [PMID:8587995, PMID:8720076] +synonym: "rhamnogalacturonase B activity" EXACT [PMID:8587995] +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0046577 +name: long-chain-alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O." [EC:1.1.3.20] +synonym: "fatty alcohol oxidase activity" EXACT [] +synonym: "fatty alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.20] +synonym: "long-chain fatty acid oxidase activity" EXACT [EC:1.1.3.20] +synonym: "long-chain fatty alcohol oxidase activity" EXACT [] +synonym: "long-chain-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.20] +xref: EC:1.1.3.20 +xref: MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0046578 +name: regulation of Ras protein signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] +is_a: GO:0051056 ! regulation of small GTPase mediated signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007265 ! Ras protein signal transduction +relationship: regulates GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0046579 +name: positive regulation of Ras protein signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] +synonym: "activation of Ras protein signal transduction" NARROW [] +synonym: "stimulation of Ras protein signal transduction" NARROW [] +synonym: "up regulation of Ras protein signal transduction" EXACT [] +synonym: "up-regulation of Ras protein signal transduction" EXACT [] +synonym: "upregulation of Ras protein signal transduction" EXACT [] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +is_a: GO:0051057 ! positive regulation of small GTPase mediated signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007265 ! Ras protein signal transduction +relationship: positively_regulates GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0046580 +name: negative regulation of Ras protein signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] +synonym: "down regulation of Ras protein signal transduction" EXACT [] +synonym: "down-regulation of Ras protein signal transduction" EXACT [] +synonym: "downregulation of Ras protein signal transduction" EXACT [] +synonym: "inhibition of Ras protein signal transduction" NARROW [] +is_a: GO:0046578 ! regulation of Ras protein signal transduction +is_a: GO:0051058 ! negative regulation of small GTPase mediated signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007265 ! Ras protein signal transduction +relationship: negatively_regulates GO:0007265 ! Ras protein signal transduction + +[Term] +id: GO:0046581 +name: intercellular canaliculus +namespace: cellular_component +def: "An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates." [ISBN:0721662544] +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0046583 +name: cation efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "cation efflux permease activity" EXACT [] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity + +[Term] +id: GO:0046584 +name: enniatin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores." [ISBN:0198506732] +synonym: "enniatin metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:0050761 ! depsipeptide metabolic process +is_a: GO:1901334 ! lactone metabolic process + +[Term] +id: GO:0046585 +name: enniatin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores." [ISBN:0198506732] +synonym: "enniatin anabolism" EXACT [] +synonym: "enniatin biosynthesis" EXACT [] +synonym: "enniatin formation" EXACT [] +synonym: "enniatin synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0046584 ! enniatin metabolic process +is_a: GO:0050763 ! depsipeptide biosynthetic process +is_a: GO:1901336 ! lactone biosynthetic process + +[Term] +id: GO:0046586 +name: regulation of calcium-dependent cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction." [GOC:ai] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules +relationship: regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules + +[Term] +id: GO:0046587 +name: positive regulation of calcium-dependent cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion." [GOC:ai] +synonym: "activation of calcium-dependent cell-cell adhesion" NARROW [] +synonym: "stimulation of calcium-dependent cell-cell adhesion" NARROW [] +synonym: "up regulation of calcium-dependent cell-cell adhesion" EXACT [] +synonym: "up-regulation of calcium-dependent cell-cell adhesion" EXACT [] +synonym: "upregulation of calcium-dependent cell-cell adhesion" EXACT [] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0046586 ! regulation of calcium-dependent cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules +relationship: positively_regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules + +[Term] +id: GO:0046588 +name: negative regulation of calcium-dependent cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion." [GOC:ai] +synonym: "down regulation of calcium-dependent cell-cell adhesion" EXACT [] +synonym: "down-regulation of calcium-dependent cell-cell adhesion" EXACT [] +synonym: "downregulation of calcium-dependent cell-cell adhesion" EXACT [] +synonym: "inhibition of calcium-dependent cell-cell adhesion" NARROW [] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0046586 ! regulation of calcium-dependent cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules +relationship: negatively_regulates GO:0016339 ! calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules + +[Term] +id: GO:0046589 +name: ribonuclease T1 activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.3] +synonym: "Aspergillus oryzae ribonuclease activity" NARROW [EC:3.1.27.3] +synonym: "binase activity" EXACT [EC:3.1.27.3] +synonym: "guanyl-specific RNase activity" EXACT [EC:3.1.27.3] +synonym: "guanyloribonuclease activity" EXACT [EC:3.1.27.3] +synonym: "ribonuclease C2" RELATED [EC:3.1.27.3] +synonym: "ribonuclease Ch" RELATED [EC:3.1.27.3] +synonym: "ribonuclease F1" EXACT [] +synonym: "ribonuclease guaninenucleotido-2'-transferase (cyclizing)" EXACT [EC:3.1.27.3] +synonym: "ribonuclease N1" RELATED [EC:3.1.27.3] +synonym: "ribonuclease N3" RELATED [EC:3.1.27.3] +synonym: "ribonuclease PP1" RELATED [EC:3.1.27.3] +synonym: "ribonuclease SA" RELATED [EC:3.1.27.3] +synonym: "ribonuclease U1" RELATED [EC:3.1.27.3] +synonym: "RNase F1" RELATED [EC:3.1.27.3] +synonym: "RNase G" RELATED [EC:3.1.27.3] +synonym: "RNase N1 activity" EXACT [EC:3.1.27.3] +synonym: "RNase N2 activity" EXACT [EC:3.1.27.3] +synonym: "RNase Sa" RELATED [EC:3.1.27.3] +synonym: "RNase T1" RELATED [EC:3.1.27.3] +synonym: "RNase T1 activity" EXACT [] +xref: EC:3.1.27.3 +xref: MetaCyc:3.1.27.3-RXN +is_a: GO:0004540 ! ribonuclease activity + +[Term] +id: GO:0046590 +name: obsolete embryonic leg morphogenesis +namespace: biological_process +def: "OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands." [GOC:bf] +comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. +synonym: "embryonic leg morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0030326 +consider: GO:0035116 + +[Term] +id: GO:0046591 +name: obsolete embryonic leg joint morphogenesis +namespace: biological_process +def: "OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner." [GOC:bf, ISBN:0582227089, PMID:12051824] +comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. +synonym: "embryonic leg joint morphogenesis" EXACT [] +is_obsolete: true +consider: GO:0036023 + +[Term] +id: GO:0046592 +name: polyamine oxidase activity +namespace: molecular_function +def: "Catalysis of the oxidative degradation or interconversion of polyamines." [EC:1.5.3.11, PMID:1567380] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "1-N-acetylspermidine:oxygen oxidoreductase (deaminating)" NARROW [EC:1.5.3.11] +synonym: "N1-acetylspermidine:oxygen oxidoreductase (deaminating)" NARROW [EC:1.5.3.11] +xref: EC:1.5.3.11 +xref: MetaCyc:POLYAMINE-OXIDASE-RXN +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0046593 +name: mandelonitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde." [EC:4.1.2.10] +synonym: "(R)-oxynitrilase activity" EXACT [EC:4.1.2.10] +synonym: "D-alpha-hydroxynitrile lyase activity" EXACT [EC:4.1.2.10] +synonym: "D-oxynitrilase activity" EXACT [EC:4.1.2.10] +synonym: "hydroxynitrile lyase activity" BROAD [] +synonym: "mandelonitrile benzaldehyde-lyase (cyanide-forming)" EXACT [EC:4.1.2.10] +synonym: "mandelonitrile benzaldehyde-lyase activity" EXACT [EC:4.1.2.10] +xref: EC:4.1.2.10 +xref: MetaCyc:MANDELONITRILE-LYASE-RXN +xref: RHEA:18313 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0046594 +name: maintenance of pole plasm mRNA location +namespace: biological_process +alt_id: GO:0048122 +def: "The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:dph, GOC:tb] +synonym: "maintenance of oocyte pole plasm mRNA localization" EXACT [] +synonym: "maintenance of pole plasm mRNA localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051237 ! maintenance of RNA location +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0019094 ! pole plasm mRNA localization + +[Term] +id: GO:0046595 +name: establishment of pole plasm mRNA localization +namespace: biological_process +alt_id: GO:0048121 +def: "Any process that results in the directed movement of mRNA to the oocyte pole plasm." [GOC:bf] +synonym: "establishment of oocyte pole plasm mRNA localization" EXACT [] +synonym: "establishment of pole plasm mRNA localisation" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051236 ! establishment of RNA localization +is_a: GO:0051649 ! establishment of localization in cell +relationship: part_of GO:0019094 ! pole plasm mRNA localization + +[Term] +id: GO:0046596 +name: regulation of viral entry into host cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the viral entry into the host cell." [GOC:jl] +synonym: "regulation of viral penetration into host cell" EXACT [] +synonym: "viral escort protein" RELATED [GOC:bm] +is_a: GO:0052372 ! modulation by symbiont of entry into host +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046718 ! viral entry into host cell +relationship: regulates GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0046597 +name: negative regulation of viral entry into host cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell." [GOC:jl] +synonym: "negative regulation of viral penetration into host cell" EXACT [] +is_a: GO:0046596 ! regulation of viral entry into host cell +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046718 ! viral entry into host cell +relationship: negatively_regulates GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0046598 +name: positive regulation of viral entry into host cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell." [GOC:jl] +synonym: "positive regulation of viral penetration into host cell" EXACT [] +is_a: GO:0046596 ! regulation of viral entry into host cell +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0046718 ! viral entry into host cell +relationship: positively_regulates GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0046599 +name: regulation of centriole replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole." [GOC:ai] +is_a: GO:0010824 ! regulation of centrosome duplication +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007099 ! centriole replication +relationship: regulates GO:0007099 ! centriole replication + +[Term] +id: GO:0046600 +name: negative regulation of centriole replication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication." [GOC:ai] +synonym: "down regulation of centriole replication" EXACT [] +synonym: "down-regulation of centriole replication" EXACT [] +synonym: "downregulation of centriole replication" EXACT [] +synonym: "inhibition of centriole replication" NARROW [] +is_a: GO:0010826 ! negative regulation of centrosome duplication +is_a: GO:0046599 ! regulation of centriole replication +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007099 ! centriole replication +relationship: negatively_regulates GO:0007099 ! centriole replication + +[Term] +id: GO:0046601 +name: positive regulation of centriole replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of centriole replication." [GOC:ai] +synonym: "activation of centriole replication" NARROW [] +synonym: "stimulation of centriole replication" NARROW [] +synonym: "up regulation of centriole replication" EXACT [] +synonym: "up-regulation of centriole replication" EXACT [] +synonym: "upregulation of centriole replication" EXACT [] +is_a: GO:0010825 ! positive regulation of centrosome duplication +is_a: GO:0046599 ! regulation of centriole replication +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007099 ! centriole replication +relationship: positively_regulates GO:0007099 ! centriole replication + +[Term] +id: GO:0046602 +name: regulation of mitotic centrosome separation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis." [GOC:ai] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:0046605 ! regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007100 ! mitotic centrosome separation +relationship: regulates GO:0007100 ! mitotic centrosome separation + +[Term] +id: GO:0046603 +name: negative regulation of mitotic centrosome separation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation." [GOC:ai] +synonym: "down regulation of mitotic centrosome separation" EXACT [] +synonym: "down-regulation of mitotic centrosome separation" EXACT [] +synonym: "downregulation of mitotic centrosome separation" EXACT [] +synonym: "inhibition of mitotic centrosome separation" NARROW [] +is_a: GO:0045839 ! negative regulation of mitotic nuclear division +is_a: GO:0046602 ! regulation of mitotic centrosome separation +is_a: GO:0046606 ! negative regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007100 ! mitotic centrosome separation +relationship: negatively_regulates GO:0007100 ! mitotic centrosome separation + +[Term] +id: GO:0046604 +name: positive regulation of mitotic centrosome separation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of centrosome separation." [GOC:ai] +synonym: "activation of mitotic centrosome separation" NARROW [] +synonym: "stimulation of mitotic centrosome separation" NARROW [] +synonym: "up regulation of mitotic centrosome separation" EXACT [] +synonym: "up-regulation of mitotic centrosome separation" EXACT [] +synonym: "upregulation of mitotic centrosome separation" EXACT [] +is_a: GO:0045840 ! positive regulation of mitotic nuclear division +is_a: GO:0046602 ! regulation of mitotic centrosome separation +is_a: GO:0046607 ! positive regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007100 ! mitotic centrosome separation +relationship: positively_regulates GO:0007100 ! mitotic centrosome separation + +[Term] +id: GO:0046605 +name: regulation of centrosome cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation." [GOC:ai] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007098 ! centrosome cycle +relationship: regulates GO:0007098 ! centrosome cycle +property_value: RO:0002161 NCBITaxon:27896 +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0046606 +name: negative regulation of centrosome cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle." [GOC:ai] +synonym: "down regulation of centrosome cycle" EXACT [] +synonym: "down-regulation of centrosome cycle" EXACT [] +synonym: "downregulation of centrosome cycle" EXACT [] +synonym: "inhibition of centrosome cycle" NARROW [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0046605 ! regulation of centrosome cycle +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007098 ! centrosome cycle +relationship: negatively_regulates GO:0007098 ! centrosome cycle + +[Term] +id: GO:0046607 +name: positive regulation of centrosome cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the centrosome cycle." [GOC:ai] +synonym: "activation of centrosome cycle" NARROW [] +synonym: "stimulation of centrosome cycle" NARROW [] +synonym: "up regulation of centrosome cycle" EXACT [] +synonym: "up-regulation of centrosome cycle" EXACT [] +synonym: "upregulation of centrosome cycle" EXACT [] +is_a: GO:0046605 ! regulation of centrosome cycle +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007098 ! centrosome cycle +relationship: positively_regulates GO:0007098 ! centrosome cycle + +[Term] +id: GO:0046608 +name: carotenoid isomerase activity +namespace: molecular_function +def: "Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids." [PMID:11884677] +is_a: GO:0016859 ! cis-trans isomerase activity +property_value: RO:0002161 NCBITaxon:4896 +property_value: RO:0002161 NCBITaxon:4932 + +[Term] +id: GO:0046609 +name: obsolete voltage-gated sulfate antiporter activity +namespace: molecular_function +def: "OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential." [GOC:mah] +comment: This term was obsoleted because there is no evidence that this function exists. +synonym: "prestin" NARROW [] +synonym: "voltage gated sulfate antiporter activity" EXACT [] +synonym: "voltage-dependent sulfate antiporter activity" EXACT [] +synonym: "voltage-sensitive sulfate antiporter activity" EXACT [] +synonym: "voltage-sensitive sulphate antiporter activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046610 +name: lysosomal proton-transporting V-type ATPase, V0 domain +namespace: cellular_component +def: "The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane." [GOC:mah] +synonym: "lysosomal hydrogen ion-transporting ATPase V0 domain" EXACT [] +is_a: GO:0000220 ! vacuolar proton-transporting V-type ATPase, V0 domain +intersection_of: GO:0033179 ! proton-transporting V-type ATPase, V0 domain +intersection_of: part_of GO:0005764 ! lysosome +relationship: part_of GO:0046611 ! lysosomal proton-transporting V-type ATPase complex + +[Term] +id: GO:0046611 +name: lysosomal proton-transporting V-type ATPase complex +namespace: cellular_component +def: "A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen." [GOC:mah, ISBN:0716743663, PMID:16449553] +synonym: "lysosomal hydrogen-translocating V-type ATPase complex" EXACT [] +synonym: "lysosomal membrane hydrogen-transporting ATPase" BROAD [] +is_a: GO:0016471 ! vacuolar proton-transporting V-type ATPase complex +intersection_of: GO:0033176 ! proton-transporting V-type ATPase complex +intersection_of: part_of GO:0005764 ! lysosome +relationship: part_of GO:0005765 ! lysosomal membrane + +[Term] +id: GO:0046612 +name: lysosomal proton-transporting V-type ATPase, V1 domain +namespace: cellular_component +def: "The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane." [GOC:mah] +synonym: "lysosomal hydrogen ion-transporting ATPase V1 domain" EXACT [] +is_a: GO:0000221 ! vacuolar proton-transporting V-type ATPase, V1 domain +intersection_of: GO:0033180 ! proton-transporting V-type ATPase, V1 domain +intersection_of: part_of GO:0005764 ! lysosome +relationship: part_of GO:0046611 ! lysosomal proton-transporting V-type ATPase complex + +[Term] +id: GO:0046615 +name: obsolete re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. The resumption of the Saccharomyces mitotic cell division cycle by pheromone-arrested cells that have not mated." [GOC:krc, PMID:9927449] +comment: This term was made obsolete because there is no evidence that this process is unique to Saccharomyces. +synonym: "re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)" EXACT [] +is_obsolete: true +replaced_by: GO:0000321 + +[Term] +id: GO:0046617 +name: obsolete nucleolar size increase (sensu Saccharomyces) +namespace: biological_process +def: "OBSOLETE. The process of nucleolar expansion, as seen in Saccharomyces." [GOC:ai] +comment: This term was made obsolete because it does not describe a biological process. +synonym: "nucleolar size increase (sensu Saccharomyces)" EXACT [] +is_obsolete: true +consider: GO:0007571 +consider: GO:0007576 + +[Term] +id: GO:0046618 +name: drug export +namespace: biological_process +def: "The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle." [GOC:go_curators] +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0046619 +name: optic placode formation involved in camera-type eye formation +namespace: biological_process +def: "Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] +synonym: "optic placode formation in camera-type eye" EXACT [] +synonym: "optic placode formation involved in camera-style eye" EXACT [] +is_a: GO:0001743 ! optic placode formation +relationship: part_of GO:0060900 ! embryonic camera-type eye formation + +[Term] +id: GO:0046620 +name: regulation of organ growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035265 ! organ growth +relationship: regulates GO:0035265 ! organ growth + +[Term] +id: GO:0046621 +name: negative regulation of organ growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035265 ! organ growth +relationship: negatively_regulates GO:0035265 ! organ growth + +[Term] +id: GO:0046622 +name: positive regulation of organ growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035265 ! organ growth +relationship: positively_regulates GO:0035265 ! organ growth + +[Term] +id: GO:0046623 +name: sphingolipid floppase activity +namespace: molecular_function +def: "Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:ai, PMID:12034738] +synonym: "sphingolipid flippase activity" EXACT [] +synonym: "sphingolipid floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "sphingolipid-translocating ATPase activity" RELATED [] +is_a: GO:0046624 ! sphingolipid transporter activity +is_a: GO:0140328 ! floppase activity +relationship: part_of GO:0099039 ! sphingolipid translocation + +[Term] +id: GO:0046624 +name: sphingolipid transporter activity +namespace: molecular_function +def: "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ai, ISBN:0198506732] +is_a: GO:0005319 ! lipid transporter activity + +[Term] +id: GO:0046625 +name: sphingolipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [ISBN:0198506732] +is_a: GO:0008289 ! lipid binding + +[Term] +id: GO:0046626 +name: regulation of insulin receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of insulin receptor signaling." [GOC:bf] +synonym: "regulation of insulin receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1900076 ! regulation of cellular response to insulin stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008286 ! insulin receptor signaling pathway +relationship: regulates GO:0008286 ! insulin receptor signaling pathway + +[Term] +id: GO:0046627 +name: negative regulation of insulin receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling." [GOC:bf] +synonym: "down regulation of insulin receptor signaling pathway" EXACT [] +synonym: "down-regulation of insulin receptor signaling pathway" EXACT [] +synonym: "downregulation of insulin receptor signaling pathway" EXACT [] +synonym: "inhibition of insulin receptor signaling pathway" NARROW [] +synonym: "negative regulation of insulin receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0046626 ! regulation of insulin receptor signaling pathway +is_a: GO:1900077 ! negative regulation of cellular response to insulin stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008286 ! insulin receptor signaling pathway +relationship: negatively_regulates GO:0008286 ! insulin receptor signaling pathway + +[Term] +id: GO:0046628 +name: positive regulation of insulin receptor signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of insulin receptor signaling." [GOC:bf] +synonym: "activation of insulin receptor signaling pathway" NARROW [] +synonym: "positive regulation of insulin receptor signalling pathway" EXACT [] +synonym: "stimulation of insulin receptor signaling pathway" NARROW [] +synonym: "up regulation of insulin receptor signaling pathway" EXACT [] +synonym: "up-regulation of insulin receptor signaling pathway" EXACT [] +synonym: "upregulation of insulin receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0046626 ! regulation of insulin receptor signaling pathway +is_a: GO:1900078 ! positive regulation of cellular response to insulin stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008286 ! insulin receptor signaling pathway +relationship: positively_regulates GO:0008286 ! insulin receptor signaling pathway + +[Term] +id: GO:0046629 +name: gamma-delta T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:add] +synonym: "gamma-delta T lymphocyte activation" EXACT [] +synonym: "gamma-delta T-cell activation" EXACT [] +synonym: "gamma-delta T-lymphocyte activation" EXACT [] +is_a: GO:0042110 ! T cell activation + +[Term] +id: GO:0046630 +name: gamma-delta T cell proliferation +namespace: biological_process +def: "The expansion of a gamma-delta T cell population by cell division." [GOC:ai] +synonym: "gamma-delta T lymphocyte proliferation" EXACT [] +synonym: "gamma-delta T-cell proliferation" EXACT [] +synonym: "gamma-delta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042098 ! T cell proliferation +is_a: GO:0046629 ! gamma-delta T cell activation + +[Term] +id: GO:0046631 +name: alpha-beta T cell activation +namespace: biological_process +def: "The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:add] +synonym: "alpha-beta T lymphocyte activation" EXACT [] +synonym: "alpha-beta T-cell activation" EXACT [] +synonym: "alpha-beta T-lymphocyte activation" EXACT [] +is_a: GO:0042110 ! T cell activation + +[Term] +id: GO:0046632 +name: alpha-beta T cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex." [CL:0000789, GOC:ai] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "alpha-beta T cell development" RELATED [GOC:add] +synonym: "alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "alpha-beta T-cell differentiation" EXACT [] +synonym: "alpha-beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0030217 ! T cell differentiation +is_a: GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0046633 +name: alpha-beta T cell proliferation +namespace: biological_process +def: "The expansion of an alpha-beta T cell population by cell division." [GOC:ai] +synonym: "alpha-beta T lymphocyte proliferation" EXACT [] +synonym: "alpha-beta T-cell proliferation" EXACT [] +synonym: "alpha-beta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042098 ! T cell proliferation +is_a: GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0046634 +name: regulation of alpha-beta T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] +synonym: "regulation of alpha-beta T lymphocyte activation" EXACT [] +synonym: "regulation of alpha-beta T-cell activation" EXACT [] +synonym: "regulation of alpha-beta T-lymphocyte activation" EXACT [] +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046631 ! alpha-beta T cell activation +relationship: regulates GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0046635 +name: positive regulation of alpha-beta T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] +synonym: "activation of alpha-beta T cell activation" NARROW [] +synonym: "positive regulation of alpha-beta T lymphocyte activation" EXACT [] +synonym: "positive regulation of alpha-beta T-cell activation" EXACT [] +synonym: "positive regulation of alpha-beta T-lymphocyte activation" EXACT [] +synonym: "stimulation of alpha-beta T cell activation" NARROW [] +synonym: "up regulation of alpha-beta T cell activation" EXACT [] +synonym: "up-regulation of alpha-beta T cell activation" EXACT [] +synonym: "upregulation of alpha-beta T cell activation" EXACT [] +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +is_a: GO:0050870 ! positive regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046631 ! alpha-beta T cell activation +relationship: positively_regulates GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0046636 +name: negative regulation of alpha-beta T cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] +synonym: "down regulation of alpha-beta T cell activation" EXACT [] +synonym: "down-regulation of alpha-beta T cell activation" EXACT [] +synonym: "downregulation of alpha-beta T cell activation" EXACT [] +synonym: "inhibition of alpha-beta T cell activation" NARROW [] +synonym: "negative regulation of alpha-beta T lymphocyte activation" EXACT [] +synonym: "negative regulation of alpha-beta T-cell activation" EXACT [] +synonym: "negative regulation of alpha-beta T-lymphocyte activation" EXACT [] +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +is_a: GO:0050868 ! negative regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046631 ! alpha-beta T cell activation +relationship: negatively_regulates GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0046637 +name: regulation of alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of alpha-beta T cell development" RELATED [GOC:add] +synonym: "regulation of alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "regulation of alpha-beta T-cell differentiation" EXACT [] +synonym: "regulation of alpha-beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046632 ! alpha-beta T cell differentiation +relationship: regulates GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0046638 +name: positive regulation of alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of alpha-beta T cell differentiation" NARROW [] +synonym: "positive regulation of alpha-beta T cell development" RELATED [GOC:add] +synonym: "positive regulation of alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of alpha-beta T-cell differentiation" EXACT [] +synonym: "positive regulation of alpha-beta T-lymphocyte differentiation" EXACT [] +synonym: "stimulation of alpha-beta T cell differentiation" NARROW [] +synonym: "up regulation of alpha-beta T cell differentiation" EXACT [] +synonym: "up-regulation of alpha-beta T cell differentiation" EXACT [] +synonym: "upregulation of alpha-beta T cell differentiation" EXACT [] +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:0046635 ! positive regulation of alpha-beta T cell activation +is_a: GO:0046637 ! regulation of alpha-beta T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046632 ! alpha-beta T cell differentiation +relationship: positively_regulates GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0046639 +name: negative regulation of alpha-beta T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of alpha-beta T cell differentiation" EXACT [] +synonym: "down-regulation of alpha-beta T cell differentiation" EXACT [] +synonym: "downregulation of alpha-beta T cell differentiation" EXACT [] +synonym: "inhibition of alpha-beta T cell differentiation" NARROW [] +synonym: "negative regulation of alpha-beta T cell development" RELATED [GOC:add] +synonym: "negative regulation of alpha-beta T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of alpha-beta T-cell differentiation" EXACT [] +synonym: "negative regulation of alpha-beta T-lymphocyte differentiation" EXACT [] +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:0046636 ! negative regulation of alpha-beta T cell activation +is_a: GO:0046637 ! regulation of alpha-beta T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046632 ! alpha-beta T cell differentiation +relationship: negatively_regulates GO:0046632 ! alpha-beta T cell differentiation + +[Term] +id: GO:0046640 +name: regulation of alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] +synonym: "regulation of alpha-beta T lymphocyte proliferation" EXACT [] +synonym: "regulation of alpha-beta T-cell proliferation" EXACT [] +synonym: "regulation of alpha-beta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046633 ! alpha-beta T cell proliferation +relationship: regulates GO:0046633 ! alpha-beta T cell proliferation + +[Term] +id: GO:0046641 +name: positive regulation of alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] +synonym: "activation of alpha-beta T cell proliferation" NARROW [] +synonym: "positive regulation of alpha-beta T lymphocyte proliferation" EXACT [] +synonym: "positive regulation of alpha-beta T-cell proliferation" EXACT [] +synonym: "positive regulation of alpha-beta T-lymphocyte proliferation" EXACT [] +synonym: "stimulation of alpha-beta T cell proliferation" NARROW [] +synonym: "up regulation of alpha-beta T cell proliferation" EXACT [] +synonym: "up-regulation of alpha-beta T cell proliferation" EXACT [] +synonym: "upregulation of alpha-beta T cell proliferation" EXACT [] +is_a: GO:0042102 ! positive regulation of T cell proliferation +is_a: GO:0046635 ! positive regulation of alpha-beta T cell activation +is_a: GO:0046640 ! regulation of alpha-beta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046633 ! alpha-beta T cell proliferation +relationship: positively_regulates GO:0046633 ! alpha-beta T cell proliferation + +[Term] +id: GO:0046642 +name: negative regulation of alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] +synonym: "down regulation of alpha-beta T cell proliferation" EXACT [] +synonym: "down-regulation of alpha-beta T cell proliferation" EXACT [] +synonym: "downregulation of alpha-beta T cell proliferation" EXACT [] +synonym: "inhibition of alpha-beta T cell proliferation" NARROW [] +synonym: "negative regulation of alpha-beta T lymphocyte proliferation" EXACT [] +synonym: "negative regulation of alpha-beta T-cell proliferation" EXACT [] +synonym: "negative regulation of alpha-beta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042130 ! negative regulation of T cell proliferation +is_a: GO:0046636 ! negative regulation of alpha-beta T cell activation +is_a: GO:0046640 ! regulation of alpha-beta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046633 ! alpha-beta T cell proliferation +relationship: negatively_regulates GO:0046633 ! alpha-beta T cell proliferation + +[Term] +id: GO:0046643 +name: regulation of gamma-delta T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] +synonym: "regulation of gamma-delta T lymphocyte activation" EXACT [] +synonym: "regulation of gamma-delta T-cell activation" EXACT [] +synonym: "regulation of gamma-delta T-lymphocyte activation" EXACT [] +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046629 ! gamma-delta T cell activation +relationship: regulates GO:0046629 ! gamma-delta T cell activation + +[Term] +id: GO:0046644 +name: negative regulation of gamma-delta T cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] +synonym: "down regulation of gamma-delta T cell activation" EXACT [] +synonym: "down-regulation of gamma-delta T cell activation" EXACT [] +synonym: "downregulation of gamma-delta T cell activation" EXACT [] +synonym: "inhibition of gamma-delta T cell activation" NARROW [] +synonym: "negative regulation of gamma-delta T lymphocyte activation" EXACT [] +synonym: "negative regulation of gamma-delta T-cell activation" EXACT [] +synonym: "negative regulation of gamma-delta T-lymphocyte activation" EXACT [] +is_a: GO:0046643 ! regulation of gamma-delta T cell activation +is_a: GO:0050868 ! negative regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046629 ! gamma-delta T cell activation +relationship: negatively_regulates GO:0046629 ! gamma-delta T cell activation + +[Term] +id: GO:0046645 +name: positive regulation of gamma-delta T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] +synonym: "activation of gamma-delta T cell activation" NARROW [] +synonym: "positive regulation of gamma-delta T lymphocyte activation" EXACT [] +synonym: "positive regulation of gamma-delta T-cell activation" EXACT [] +synonym: "positive regulation of gamma-delta T-lymphocyte activation" EXACT [] +synonym: "stimulation of gamma-delta T cell activation" NARROW [] +synonym: "up regulation of gamma-delta T cell activation" EXACT [] +synonym: "up-regulation of gamma-delta T cell activation" EXACT [] +synonym: "upregulation of gamma-delta T cell activation" EXACT [] +is_a: GO:0046643 ! regulation of gamma-delta T cell activation +is_a: GO:0050870 ! positive regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046629 ! gamma-delta T cell activation +relationship: positively_regulates GO:0046629 ! gamma-delta T cell activation + +[Term] +id: GO:0046646 +name: regulation of gamma-delta T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] +synonym: "regulation of gamma-delta T lymphocyte proliferation" EXACT [] +synonym: "regulation of gamma-delta T-cell proliferation" EXACT [] +synonym: "regulation of gamma-delta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042129 ! regulation of T cell proliferation +is_a: GO:0046643 ! regulation of gamma-delta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046630 ! gamma-delta T cell proliferation +relationship: regulates GO:0046630 ! gamma-delta T cell proliferation + +[Term] +id: GO:0046647 +name: negative regulation of gamma-delta T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] +synonym: "down regulation of gamma-delta T cell proliferation" EXACT [] +synonym: "down-regulation of gamma-delta T cell proliferation" EXACT [] +synonym: "downregulation of gamma-delta T cell proliferation" EXACT [] +synonym: "inhibition of gamma-delta T cell proliferation" NARROW [] +synonym: "negative regulation of gamma-delta T lymphocyte proliferation" EXACT [] +synonym: "negative regulation of gamma-delta T-cell proliferation" EXACT [] +synonym: "negative regulation of gamma-delta T-lymphocyte proliferation" EXACT [] +is_a: GO:0042130 ! negative regulation of T cell proliferation +is_a: GO:0046644 ! negative regulation of gamma-delta T cell activation +is_a: GO:0046646 ! regulation of gamma-delta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046630 ! gamma-delta T cell proliferation +relationship: negatively_regulates GO:0046630 ! gamma-delta T cell proliferation + +[Term] +id: GO:0046648 +name: positive regulation of gamma-delta T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] +synonym: "activation of gamma-delta T cell proliferation" NARROW [] +synonym: "positive regulation of gamma-delta T lymphocyte proliferation" EXACT [] +synonym: "positive regulation of gamma-delta T-cell proliferation" EXACT [] +synonym: "positive regulation of gamma-delta T-lymphocyte proliferation" EXACT [] +synonym: "stimulation of gamma-delta T cell proliferation" NARROW [] +synonym: "up regulation of gamma-delta T cell proliferation" EXACT [] +synonym: "up-regulation of gamma-delta T cell proliferation" EXACT [] +synonym: "upregulation of gamma-delta T cell proliferation" EXACT [] +is_a: GO:0042102 ! positive regulation of T cell proliferation +is_a: GO:0046645 ! positive regulation of gamma-delta T cell activation +is_a: GO:0046646 ! regulation of gamma-delta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046630 ! gamma-delta T cell proliferation +relationship: positively_regulates GO:0046630 ! gamma-delta T cell proliferation + +[Term] +id: GO:0046649 +name: lymphocyte activation +namespace: biological_process +def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] +is_a: GO:0045321 ! leukocyte activation + +[Term] +id: GO:0046651 +name: lymphocyte proliferation +namespace: biological_process +def: "The expansion of a lymphocyte population by cell division." [GOC:ai] +is_a: GO:0032943 ! mononuclear cell proliferation +is_a: GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0046653 +name: tetrahydrofolate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group." [ISBN:0198506732] +synonym: "tetrahydrofolate metabolism" EXACT [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process + +[Term] +id: GO:0046654 +name: tetrahydrofolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group." [ISBN:0198506732] +synonym: "tetrahydrofolate anabolism" EXACT [] +synonym: "tetrahydrofolate biosynthesis" EXACT [] +synonym: "tetrahydrofolate formation" EXACT [] +synonym: "tetrahydrofolate synthesis" EXACT [] +xref: MetaCyc:FOLSYN-PWY +is_a: GO:0009396 ! folic acid-containing compound biosynthetic process +is_a: GO:0046653 ! tetrahydrofolate metabolic process + +[Term] +id: GO:0046655 +name: folic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [ISBN:0198506732] +synonym: "folate metabolic process" EXACT [] +synonym: "folate metabolism" EXACT [] +synonym: "folic acid metabolism" EXACT [] +synonym: "vitamin B9 metabolic process" EXACT [] +synonym: "vitamin B9 metabolism" EXACT [] +synonym: "vitamin M metabolic process" EXACT [] +synonym: "vitamin M metabolism" EXACT [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process + +[Term] +id: GO:0046656 +name: folic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid." [GOC:ai] +synonym: "folate biosynthesis" EXACT [] +synonym: "folate biosynthetic process" EXACT [] +synonym: "folic acid anabolism" EXACT [] +synonym: "folic acid biosynthesis" EXACT [] +synonym: "folic acid formation" EXACT [] +synonym: "folic acid synthesis" EXACT [] +synonym: "vitamin B9 biosynthesis" EXACT [] +synonym: "vitamin B9 biosynthetic process" EXACT [] +synonym: "vitamin M biosynthesis" EXACT [] +synonym: "vitamin M biosynthetic process" EXACT [] +xref: MetaCyc:FOLSYN-PWY +xref: Wikipedia:Folic_acid +is_a: GO:0009396 ! folic acid-containing compound biosynthetic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046655 ! folic acid metabolic process + +[Term] +id: GO:0046657 +name: folic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid." [GOC:ai] +synonym: "folate catabolic process" EXACT [] +synonym: "folate catabolism" EXACT [] +synonym: "folic acid breakdown" EXACT [] +synonym: "folic acid catabolism" EXACT [] +synonym: "folic acid degradation" EXACT [] +synonym: "vitamin B9 catabolic process" EXACT [] +synonym: "vitamin B9 catabolism" EXACT [] +synonym: "vitamin M catabolic process" EXACT [] +synonym: "vitamin M catabolism" EXACT [] +is_a: GO:0009397 ! folic acid-containing compound catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:0046655 ! folic acid metabolic process + +[Term] +id: GO:0046658 +name: anchored component of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos, GOC:mah] +synonym: "anchored to plasma membrane" NARROW [] +synonym: "plasma membrane, GPI-anchored" NARROW [] +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0046659 +name: digestive hormone activity +namespace: molecular_function +def: "The action characteristic of a hormone that takes part in the digestion process." [GOC:ai] +synonym: "secretin" NARROW [] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0046660 +name: female sex differentiation +namespace: biological_process +def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf] +is_a: GO:0007548 ! sex differentiation +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0046661 +name: male sex differentiation +namespace: biological_process +def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf] +is_a: GO:0007548 ! sex differentiation +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0046662 +name: regulation of oviposition +namespace: biological_process +alt_id: GO:0048042 +def: "Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium." [GOC:dph, GOC:tb, PMID:11932766] +synonym: "regulation of post-mating oviposition" NARROW [] +is_a: GO:0050795 ! regulation of behavior +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018991 ! oviposition +relationship: regulates GO:0018991 ! oviposition + +[Term] +id: GO:0046663 +name: dorsal closure, leading edge cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure." [GOC:ai, PMID:12147138] +is_a: GO:0035026 ! leading edge cell differentiation +intersection_of: GO:0035026 ! leading edge cell differentiation +intersection_of: part_of GO:0007391 ! dorsal closure +relationship: part_of GO:0007392 ! initiation of dorsal closure + +[Term] +id: GO:0046664 +name: dorsal closure, amnioserosa morphology change +namespace: biological_process +def: "The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo." [PMID:12147138] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0007391 ! dorsal closure + +[Term] +id: GO:0046665 +name: amnioserosa maintenance +namespace: biological_process +def: "Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis." [GOC:bf] +is_a: GO:0001894 ! tissue homeostasis +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm + +[Term] +id: GO:0046666 +name: retinal cell programmed cell death +namespace: biological_process +def: "Programmed cell death that occurs in the developing retina." [GOC:bf] +synonym: "programmed cell death, retina cells" EXACT [] +synonym: "programmed cell death, retinal cells" EXACT [] +synonym: "retina cell programmed cell death" EXACT [] +synonym: "retina programmed cell death" EXACT [] +synonym: "retinal programmed cell death" EXACT [] +is_a: GO:0010623 ! programmed cell death involved in cell development +relationship: part_of GO:0048592 ! eye morphogenesis + +[Term] +id: GO:0046667 +name: compound eye retinal cell programmed cell death +namespace: biological_process +def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672] +is_a: GO:0046666 ! retinal cell programmed cell death +relationship: part_of GO:0001745 ! compound eye morphogenesis + +[Term] +id: GO:0046668 +name: regulation of retinal cell programmed cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] +synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046666 ! retinal cell programmed cell death +relationship: regulates GO:0046666 ! retinal cell programmed cell death + +[Term] +id: GO:0046669 +name: regulation of compound eye retinal cell programmed cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] +synonym: "regulation of retinal cell programmed cell death" BROAD [] +is_a: GO:0046668 ! regulation of retinal cell programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046667 ! compound eye retinal cell programmed cell death +relationship: regulates GO:0046667 ! compound eye retinal cell programmed cell death + +[Term] +id: GO:0046670 +name: positive regulation of retinal cell programmed cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] +synonym: "activation of retinal programmed cell death" NARROW [] +synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] +synonym: "stimulation of retinal programmed cell death" NARROW [] +synonym: "up regulation of retinal programmed cell death" EXACT [] +synonym: "up-regulation of retinal programmed cell death" EXACT [] +synonym: "upregulation of retinal programmed cell death" EXACT [] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:0046668 ! regulation of retinal cell programmed cell death +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046666 ! retinal cell programmed cell death +relationship: positively_regulates GO:0046666 ! retinal cell programmed cell death + +[Term] +id: GO:0046671 +name: negative regulation of retinal cell programmed cell death +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] +synonym: "down regulation of retinal programmed cell death" EXACT [] +synonym: "down-regulation of retinal programmed cell death" EXACT [] +synonym: "downregulation of retinal programmed cell death" EXACT [] +synonym: "inhibition of retinal programmed cell death" NARROW [] +synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0046668 ! regulation of retinal cell programmed cell death +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046666 ! retinal cell programmed cell death +relationship: negatively_regulates GO:0046666 ! retinal cell programmed cell death + +[Term] +id: GO:0046672 +name: positive regulation of compound eye retinal cell programmed cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] +synonym: "activation of retinal cell programmed cell death" BROAD [] +synonym: "positive regulation of retinal cell programmed cell death" BROAD [] +synonym: "stimulation of retinal cell programmed cell death" BROAD [] +synonym: "up regulation of retinal cell programmed cell death" BROAD [] +synonym: "up-regulation of retinal cell programmed cell death" BROAD [] +synonym: "upregulation of retinal cell programmed cell death" BROAD [] +is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death +is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death +relationship: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death + +[Term] +id: GO:0046673 +name: negative regulation of compound eye retinal cell programmed cell death +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] +synonym: "down regulation of retinal cell programmed cell death" BROAD [] +synonym: "down-regulation of retinal cell programmed cell death" BROAD [] +synonym: "downregulation of retinal cell programmed cell death" BROAD [] +synonym: "inhibition of retinal cell programmed cell death" BROAD [] +synonym: "negative regulation of retina cell programmed cell death" BROAD [] +synonym: "negative regulation of retinal cell programmed cell death" BROAD [] +is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death +is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death +relationship: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death + +[Term] +id: GO:0046676 +name: negative regulation of insulin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] +synonym: "down regulation of insulin secretion" EXACT [] +synonym: "down-regulation of insulin secretion" EXACT [] +synonym: "downregulation of insulin secretion" EXACT [] +synonym: "inhibition of insulin secretion" NARROW [] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0050796 ! regulation of insulin secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030073 ! insulin secretion +relationship: negatively_regulates GO:0030073 ! insulin secretion + +[Term] +id: GO:0046677 +name: response to antibiotic +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms." [GOC:ai, GOC:ef] +subset: goslim_chembl +synonym: "antibiotic susceptibility/resistance" RELATED [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0046678 +name: response to bacteriocin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation." [ISBN:0721662544] +synonym: "bacteriocin susceptibility/resistance" RELATED [] +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901652 ! response to peptide + +[Term] +id: GO:0046679 +name: response to streptomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome." [GOC:curators] +synonym: "streptomycin susceptibility/resistance" RELATED [] +is_a: GO:0042493 ! response to drug +is_a: GO:0060992 ! response to fungicide +is_a: GO:1903416 ! response to glycoside + +[Term] +id: GO:0046680 +name: response to DDT +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals." [ISBN:0721662544] +synonym: "DDT resistance" RELATED [] +synonym: "DDT susceptibility/resistance" RELATED [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0017085 ! response to insecticide +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0046681 +name: response to carbamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] +synonym: "carbamate resistance" RELATED [] +synonym: "carbamate susceptibility/resistance" RELATED [] +is_a: GO:0017085 ! response to insecticide +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0046682 +name: response to cyclodiene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring." [ISBN:0877797099] +synonym: "cyclodiene resistance" RELATED [] +synonym: "cyclodiene susceptibility/resistance" RELATED [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0017085 ! response to insecticide + +[Term] +id: GO:0046683 +name: response to organophosphorus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors." [ISBN:0721662544] +synonym: "organophosphorus resistance" RELATED [] +synonym: "organophosphorus susceptibility/resistance" RELATED [] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0046684 +name: response to pyrethroid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage." [ISBN:0721662544] +synonym: "pyrethroid resistance" RELATED [] +synonym: "pyrethroid susceptibility/resistance" RELATED [] +is_a: GO:0017085 ! response to insecticide + +[Term] +id: GO:0046685 +name: response to arsenic-containing substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:hjd, ISBN:0721662544] +synonym: "arsenate sensitivity/resistance" RELATED [] +synonym: "response to arsenic" EXACT [] +is_a: GO:0042221 ! response to chemical + +[Term] +id: GO:0046686 +name: response to cadmium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus." [GOC:ai] +synonym: "cadmium sensitivity/resistance" RELATED [] +synonym: "response to cadmium" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0046687 +name: response to chromate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus." [ISBN:0721662544] +synonym: "chromate sensitivity/resistance" RELATED [] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0046688 +name: response to copper ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus." [GOC:ai] +synonym: "copper sensitivity/resistance" RELATED [] +synonym: "response to copper" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0046689 +name: response to mercury ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus." [GOC:ai] +synonym: "mercuric sensitivity/resistance" RELATED [] +synonym: "response to mercuric ion" NARROW [GOC:mah] +synonym: "response to mercury" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0046690 +name: response to tellurium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus." [GOC:ai] +synonym: "response to tellurium" EXACT [] +synonym: "tellurium sensitivity/resistance" RELATED [] +is_a: GO:0010035 ! response to inorganic substance + +[Term] +id: GO:0046691 +name: intracellular canaliculus +namespace: cellular_component +def: "An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates." [GOC:mah, ISBN:0721662544, PMID:10700045] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016324 ! apical plasma membrane + +[Term] +id: GO:0046692 +name: sperm competition +namespace: biological_process +def: "Any process that contributes to the success of sperm fertilization in multiply-mated females." [PMID:10885514] +xref: Wikipedia:Sperm_competition +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007320 ! insemination + +[Term] +id: GO:0046693 +name: sperm storage +namespace: biological_process +def: "The retention of sperm by a female following mating." [PMID:10885514] +synonym: "retention of sperm" EXACT [] +synonym: "sequestering of sperm" EXACT [] +synonym: "sequestration of sperm" EXACT [] +synonym: "sperm retention" EXACT [] +synonym: "sperm sequestering" EXACT [] +synonym: "sperm sequestration" EXACT [] +synonym: "storage of sperm" EXACT [] +is_a: GO:0046692 ! sperm competition + +[Term] +id: GO:0046694 +name: sperm incapacitation +namespace: biological_process +def: "The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males." [PMID:10440373] +is_a: GO:0046692 ! sperm competition + +[Term] +id: GO:0046695 +name: SLIK (SAGA-like) complex +namespace: cellular_component +def: "A SAGA-type histone acetyltransferase complex that contains Rtg2 and a smaller form of Spt7 than the fungal SAGA complex, and lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction." [PMID:12101232, PMID:12186975, PMID:17337012] +comment: See also the cellular component term 'SAGA complex ; GO:0000124'. +synonym: "SAGA (alt) complex" EXACT [] +synonym: "SALSA complex" EXACT [] +synonym: "SLIK/SALSA complex" EXACT [] +is_a: GO:0070461 ! SAGA-type complex +relationship: has_part GO:0071819 ! DUBm complex +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0046696 +name: lipopolysaccharide receptor complex +namespace: cellular_component +def: "A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens." [PMID:11706042, PMID:9665271] +comment: Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of. +synonym: "LPS receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016021 ! integral component of membrane + +[Term] +id: GO:0046697 +name: decidualization +namespace: biological_process +def: "The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta." [ISBN:0721662544, PMID:11133685] +synonym: "decidual cell reaction" EXACT [] +xref: Wikipedia:Decidualization +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0001893 ! maternal placenta development + +[Term] +id: GO:0046700 +name: heterocycle catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [GOC:ai] +synonym: "heterocycle breakdown" EXACT [] +synonym: "heterocycle catabolism" EXACT [] +synonym: "heterocycle degradation" EXACT [] +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0046483 ! heterocycle metabolic process + +[Term] +id: GO:0046701 +name: insecticide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects." [GOC:ai] +synonym: "insecticide breakdown" EXACT [] +synonym: "insecticide catabolism" EXACT [] +synonym: "insecticide degradation" EXACT [] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0017143 ! insecticide metabolic process +is_a: GO:0042178 ! xenobiotic catabolic process + +[Term] +id: GO:0046702 +name: galactoside 6-L-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside." [PMID:12413479] +is_a: GO:0046921 ! alpha-(1->6)-fucosyltransferase activity + +[Term] +id: GO:0046703 +name: natural killer cell lectin-like receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lectin-like natural killer cell receptor." [GOC:ai] +synonym: "KLRC4 receptor binding" NARROW [] +synonym: "NK cell lectin-like receptor binding" EXACT [] +synonym: "NKG2D receptor binding" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0046704 +name: CDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate." [GOC:ai] +synonym: "CDP metabolism" EXACT [] +is_a: GO:0009193 ! pyrimidine ribonucleoside diphosphate metabolic process +is_a: GO:0009218 ! pyrimidine ribonucleotide metabolic process + +[Term] +id: GO:0046705 +name: CDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate." [GOC:ai] +synonym: "CDP anabolism" EXACT [] +synonym: "CDP biosynthesis" EXACT [] +synonym: "CDP formation" EXACT [] +synonym: "CDP synthesis" EXACT [] +is_a: GO:0009194 ! pyrimidine ribonucleoside diphosphate biosynthetic process +is_a: GO:0009220 ! pyrimidine ribonucleotide biosynthetic process +is_a: GO:0046704 ! CDP metabolic process + +[Term] +id: GO:0046706 +name: CDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate." [GOC:ai] +synonym: "CDP breakdown" EXACT [] +synonym: "CDP catabolism" EXACT [] +synonym: "CDP degradation" EXACT [] +is_a: GO:0009195 ! pyrimidine ribonucleoside diphosphate catabolic process +is_a: GO:0009222 ! pyrimidine ribonucleotide catabolic process +is_a: GO:0046704 ! CDP metabolic process + +[Term] +id: GO:0046707 +name: IDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving IDP, inosine 5'-diphosphate." [GOC:ai] +synonym: "IDP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009179 ! purine ribonucleoside diphosphate metabolic process + +[Term] +id: GO:0046708 +name: IDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate." [GOC:ai] +synonym: "IDP anabolism" EXACT [] +synonym: "IDP biosynthesis" EXACT [] +synonym: "IDP formation" EXACT [] +synonym: "IDP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009180 ! purine ribonucleoside diphosphate biosynthetic process +is_a: GO:0046707 ! IDP metabolic process + +[Term] +id: GO:0046709 +name: IDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate." [GOC:ai] +synonym: "IDP breakdown" EXACT [] +synonym: "IDP catabolism" EXACT [] +synonym: "IDP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009181 ! purine ribonucleoside diphosphate catabolic process +is_a: GO:0046707 ! IDP metabolic process + +[Term] +id: GO:0046710 +name: GDP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate." [GOC:ai] +synonym: "GDP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009179 ! purine ribonucleoside diphosphate metabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process + +[Term] +id: GO:0046711 +name: GDP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate." [GOC:ai] +synonym: "GDP anabolism" EXACT [] +synonym: "GDP biosynthesis" EXACT [] +synonym: "GDP formation" EXACT [] +synonym: "GDP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009180 ! purine ribonucleoside diphosphate biosynthetic process +is_a: GO:0046710 ! GDP metabolic process +is_a: GO:1901070 ! guanosine-containing compound biosynthetic process + +[Term] +id: GO:0046712 +name: GDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate." [GOC:ai] +synonym: "GDP breakdown" EXACT [] +synonym: "GDP catabolism" EXACT [] +synonym: "GDP degradation" EXACT [] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009181 ! purine ribonucleoside diphosphate catabolic process +is_a: GO:0046710 ! GDP metabolic process +is_a: GO:1901069 ! guanosine-containing compound catabolic process + +[Term] +id: GO:0046713 +name: borate transport +namespace: biological_process +def: "The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals." [PMID:21710975] +synonym: "boron transport" RELATED [] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0015893 ! drug transport + +[Term] +id: GO:0046714 +name: borate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with borate, the anion (BO3)3-." [GOC:curators] +synonym: "boron binding" RELATED [] +is_a: GO:0008144 ! drug binding +is_a: GO:0043168 ! anion binding + +[Term] +id: GO:0046715 +name: active borate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0080138 +def: "Enables the transport of borate across a membrane against the concentration gradient." [PMID:12447444] +synonym: "borate transmembrane transporter activity" BROAD [] +synonym: "borate uptake transmembrane transporter activity" RELATED [] +synonym: "boron transmembrane transporter activity" RELATED [] +synonym: "boron uptake transmembrane transporter activity" RELATED [] +synonym: "efflux-type borate transporter" NARROW [] +synonym: "efflux-type boron transporter" RELATED [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +relationship: part_of GO:0035445 ! borate transmembrane transport +created_by: dhl +creation_date: 2009-05-19T04:09:56Z + +[Term] +id: GO:0046716 +name: muscle cell cellular homeostasis +namespace: biological_process +def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901] +synonym: "muscle fiber maintenance" NARROW [GOC:dph, GOC:tb] +synonym: "muscle homeostasis" RELATED [GOC:dph] +is_a: GO:0019725 ! cellular homeostasis +is_a: GO:0060249 ! anatomical structure homeostasis +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0046717 +name: acid secretion +namespace: biological_process +def: "The controlled release of acid by a cell or a tissue." [GOC:ai] +is_a: GO:0046903 ! secretion + +[Term] +id: GO:0046718 +name: viral entry into host cell +namespace: biological_process +alt_id: GO:0019063 +def: "The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm." [GOC:jl] +comment: Viral attachment to the host cell is not part of viral entry in GO because virus attachment does not always lead to viral entry: attachment can also result in the virion being carried by the host cell to another location. +subset: goslim_metagenomics +synonym: "entry of virus into host cell" EXACT [] +synonym: "phage translocation" EXACT [] +synonym: "viral penetration" EXACT [] +synonym: "virion penetration" EXACT [] +synonym: "virion penetration into host cell" EXACT [] +synonym: "virus entry into host cell" EXACT [GOC:bf] +xref: VZ:936 +is_a: GO:0044409 ! entry into host +relationship: part_of GO:0019058 ! viral life cycle + +[Term] +id: GO:0046719 +name: regulation by virus of viral protein levels in host cell +namespace: biological_process +def: "Any virus-mediated process that modulates the levels of viral proteins in a cell." [GOC:ai] +synonym: "regulation of viral protein levels" EXACT [] +is_a: GO:0048878 ! chemical homeostasis +is_a: GO:0050792 ! regulation of viral process + +[Term] +id: GO:0046720 +name: citric acid secretion +namespace: biological_process +def: "The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue." [GOC:ai] +synonym: "citrate secretion" EXACT [] +is_a: GO:0015746 ! citrate transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0046721 +name: formic acid secretion +namespace: biological_process +def: "The controlled release of formic acid, HCOOH, by a cell or a tissue." [GOC:ai] +synonym: "formate secretion" EXACT [] +is_a: GO:0015724 ! formate transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0046722 +name: lactic acid secretion +namespace: biological_process +def: "The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue." [GOC:ai] +synonym: "lactate secretion" EXACT [] +is_a: GO:0035879 ! plasma membrane lactate transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0046723 +name: malic acid secretion +namespace: biological_process +def: "The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue." [GOC:ai] +synonym: "hydroxysuccinic acid secretion" EXACT [] +synonym: "malate secretion" EXACT [] +is_a: GO:0015743 ! malate transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0046724 +name: oxalic acid secretion +namespace: biological_process +def: "The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue." [GOC:ai] +synonym: "oxalate secretion" EXACT [] +is_a: GO:0019532 ! oxalate transport +is_a: GO:0046717 ! acid secretion + +[Term] +id: GO:0046725 +name: negative regulation by virus of viral protein levels in host cell +namespace: biological_process +def: "Any process where the infecting virus reduces the levels of viral proteins in a cell." [GOC:ai] +synonym: "down regulation of viral protein levels in host cell" EXACT [] +synonym: "down-regulation of viral protein levels in host cell" EXACT [] +synonym: "downregulation of viral protein levels in host cell" EXACT [] +synonym: "inhibition of viral protein levels in host cell" NARROW [] +synonym: "negative regulation of viral protein levels" EXACT [] +is_a: GO:0046719 ! regulation by virus of viral protein levels in host cell +is_a: GO:0048525 ! negative regulation of viral process + +[Term] +id: GO:0046726 +name: positive regulation by virus of viral protein levels in host cell +namespace: biological_process +def: "Any process where the infecting virus increases the levels of viral proteins in a cell." [GOC:ai] +synonym: "activation of viral protein levels in host cell" NARROW [] +synonym: "positive regulation of viral protein levels" EXACT [] +synonym: "stimulation of viral protein levels in host cell" NARROW [] +synonym: "up regulation of viral protein levels in host cell" EXACT [] +synonym: "up-regulation of viral protein levels in host cell" EXACT [] +synonym: "upregulation of viral protein levels in host cell" EXACT [] +is_a: GO:0046719 ! regulation by virus of viral protein levels in host cell +is_a: GO:0048524 ! positive regulation of viral process + +[Term] +id: GO:0046727 +name: capsomere +namespace: cellular_component +def: "Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses." [ISBN:0198506732] +synonym: "capsomer" EXACT [] +xref: Wikipedia:Capsomere +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019028 ! viral capsid + +[Term] +id: GO:0046729 +name: viral procapsid +namespace: cellular_component +def: "A stable empty viral capsid produced during the assembly of viruses." [ISBN:0072370319, ISBN:1555811272] +is_a: GO:0044423 ! virion part + +[Term] +id: GO:0046730 +name: induction of host immune response by virus +namespace: biological_process +alt_id: GO:0046731 +alt_id: GO:0046732 +alt_id: GO:0046733 +alt_id: GO:0046734 +alt_id: GO:0046735 +def: "The induction by a virus of an immune response in the host organism." [GOC:jl] +synonym: "activation of host immune response by virus" EXACT [] +synonym: "active induction of host immune response by virus" RELATED [] +synonym: "active viral induction of host immune response" RELATED [] +synonym: "passive activation of host immune response by virus" NARROW [] +synonym: "passive induction of cell-mediated immune response in host by virus" NARROW [] +synonym: "passive induction of host cell-mediated immune response by virus" NARROW [] +synonym: "passive induction of host humoral immune response by virus" NARROW [] +synonym: "passive induction of host immune response by virus" NARROW [] +synonym: "passive induction of host innate immune response by virus" NARROW [] +synonym: "passive induction of humoral immune response in host by virus" NARROW [] +synonym: "passive induction of innate immune response in host by virus" NARROW [] +synonym: "passive viral activation of cell-mediated immune response in host" NARROW [] +synonym: "passive viral activation of humoral immune response in host" NARROW [] +synonym: "passive viral activation of innate immune response in host" NARROW [] +synonym: "passive viral induction of cell-mediated immune response in host" NARROW [] +synonym: "passive viral induction of host immune response" NARROW [] +synonym: "passive viral induction of humoral immune response in host" NARROW [] +synonym: "passive viral induction of innate immune response in host" NARROW [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0075528 ! modulation by virus of host immune response + +[Term] +id: GO:0046736 +name: induction of humoral immune response in host by virus +namespace: biological_process +def: "The intentional, virally-encoded stimulation of a host humoral defense response to viral infection." [GOC:jl] +synonym: "active induction of humoral immune response in host by virus" RELATED [] +synonym: "active viral induction of humoral immune response in host" EXACT [] +is_a: GO:0046730 ! induction of host immune response by virus + +[Term] +id: GO:0046737 +name: induction of cell-mediated immune response in host by virus +namespace: biological_process +def: "The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection." [GOC:jl] +synonym: "active induction of cell-mediated immune response in host by virus" RELATED [] +synonym: "active viral induction of cell-mediated immune response in host" EXACT [] +is_a: GO:0046730 ! induction of host immune response by virus + +[Term] +id: GO:0046738 +name: induction of innate immune response in host by virus +namespace: biological_process +def: "The intentional, virally-encoded stimulation of an innate host defense response to viral infection." [GOC:jl] +synonym: "active induction of innate immune response in host by virus" RELATED [] +synonym: "active viral induction of innate immune response in host" EXACT [] +is_a: GO:0046730 ! induction of host immune response by virus + +[Term] +id: GO:0046739 +name: transport of virus in multicellular host +namespace: biological_process +def: "The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs)." [GOC:bf, GOC:jl, ISBN:0781718325] +synonym: "spread of virus in multicellular host" RELATED [GOC:bf, GOC:jl] +synonym: "spread of virus within multicellular host" EXACT [] +synonym: "viral spread within multicellular host" EXACT [] +is_a: GO:0044000 ! movement in host +is_a: GO:0046794 ! transport of virus + +[Term] +id: GO:0046740 +name: transport of virus in host, cell to cell +namespace: biological_process +def: "The transport of a virus between adjacent cells in a multicellular organism." [GOC:bf, GOC:jl, ISBN:0781718325] +synonym: "cell to cell spread of virus within host" EXACT [] +synonym: "intercellular virus transport" EXACT [GOC:bf, GOC:jl] +synonym: "spread of virus in host, cell to cell" RELATED [GOC:bf, GOC:jl] +synonym: "spread of virus within host, cell to cell" EXACT [] +synonym: "viral spread within host, cell to cell" EXACT [] +xref: VZ:1018 +is_a: GO:0046739 ! transport of virus in multicellular host +is_a: GO:1902586 ! multi-organism intercellular transport + +[Term] +id: GO:0046741 +name: transport of virus in host, tissue to tissue +namespace: biological_process +def: "The transport of a virus between tissues in a multicellular organism." [GOC:bf, GOC:jl, ISBN:0781718325] +synonym: "spread of virus in host, tissue to tissue" RELATED [GOC:bf, GOC:jl] +synonym: "spread of virus within host, tissue to tissue" EXACT [] +synonym: "tissue to tissue spread of virus within host" EXACT [] +synonym: "viral spread within host, tissue to tissue" EXACT [] +is_a: GO:0046739 ! transport of virus in multicellular host + +[Term] +id: GO:0046745 +name: viral capsid secondary envelopment +namespace: biological_process +alt_id: GO:0046746 +alt_id: GO:0046747 +alt_id: GO:0046748 +alt_id: GO:0046768 +alt_id: GO:0046769 +alt_id: GO:0046770 +def: "The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope." [ISBN:0072370319, ISBN:0781718325, PMID:11533156] +synonym: "endoplasmic reticulum membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "ER membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "Golgi membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "inner nuclear membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "nuclear membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "outer nuclear membrane viral budding during viral capsid re-envelopment" EXACT [] +synonym: "plasma membrane viral budding during viral capsid re-envelopment" RELATED [] +synonym: "viral budding from ER membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from ER membrane during viral capsid re-envelopment" RELATED [] +synonym: "viral budding from Golgi membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from Golgi membrane during viral capsid re-envelopment" RELATED [] +synonym: "viral budding from inner nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from inner nuclear membrane during viral capsid re-envelopment" RELATED [] +synonym: "viral budding from nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from nuclear membrane during viral capsid re-envelopment" RELATED [] +synonym: "viral budding from outer nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from outer nuclear membrane during viral capsid re-envelopment" EXACT [] +synonym: "viral budding from plasma membrane by viral capsid re-envelopment" EXACT [] +synonym: "viral budding from plasma membrane during viral capsid re-envelopment" RELATED [] +synonym: "viral capsid re-envelopment" RELATED [GOC:bf, GOC:jl] +synonym: "virus budding from ER membrane by viral capsid re-envelopment" EXACT [] +synonym: "virus budding from ER membrane during viral capsid re-envelopment" RELATED [GOC:tb] +synonym: "virus budding from Golgi membrane by viral capsid re-envelopment" EXACT [] +synonym: "virus budding from Golgi membrane during viral capsid re-envelopment" RELATED [GOC:tb] +synonym: "virus budding from inner nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "virus budding from inner nuclear membrane during viral capsid re-envelopment" RELATED [GOC:tb] +synonym: "virus budding from nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "virus budding from nuclear membrane during viral capsid re-envelopment" RELATED [GOC:tb] +synonym: "virus budding from outer nuclear membrane by viral capsid re-envelopment" EXACT [] +synonym: "virus budding from outer nuclear membrane during viral capsid re-envelopment" RELATED [GOC:tb] +synonym: "virus budding from plasma membrane during viral capsid re-envelopment" RELATED [GOC:tb] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0046752 +name: viral capsid precursor transport to host cell nucleus +namespace: biological_process +def: "Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid." [ISBN:0781718325] +synonym: "establishment and maintenance of viral capsid precursor localization in nucleus" BROAD [] +synonym: "localization of viral capsid precursors in nucleus" BROAD [] +synonym: "nuclear localization of viral capsid precursors" BROAD [] +synonym: "viral capsid precursor localisation in host cell nucleus" BROAD [GOC:mah] +synonym: "viral capsid precursor localization in host cell nucleus" BROAD [] +synonym: "viral capsid precursor localization to host cell nucleus" BROAD [GOC:bf, GOC:jl] +is_a: GO:0030581 ! symbiont intracellular protein transport in host +is_a: GO:0042000 ! translocation of peptides or proteins into host +relationship: part_of GO:0039708 ! nuclear capsid assembly + +[Term] +id: GO:0046753 +name: non-lytic viral release +namespace: biological_process +def: "The exit of a viral particle from a cell that does not involve cell lysis." [GOC:bf, GOC:jl, ISBN:0072370319] +is_a: GO:0019076 ! viral release from host cell +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18852 xsd:anyURI + +[Term] +id: GO:0046754 +name: viral exocytosis +namespace: biological_process +def: "The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis." [ISBN:0072370319] +is_a: GO:0046753 ! non-lytic viral release + +[Term] +id: GO:0046755 +name: viral budding +namespace: biological_process +alt_id: GO:0046744 +def: "A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space." [ISBN:0781718325, VZ:1947] +synonym: "viral capsid envelopment" RELATED [] +synonym: "virion budding" NARROW [] +synonym: "virus budding" RELATED [] +xref: VZ:1947 "Viral budding" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly + +[Term] +id: GO:0046757 +name: obsolete lytic virus budding from ER membrane +namespace: biological_process +def: "OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis." [ISBN:0072370319] +comment: This term was made obsolete because it does not appear to correspond to a real biological process. +synonym: "lytic endoplasmic reticulum membrane viral budding" EXACT [] +synonym: "lytic ER membrane viral budding" EXACT [] +synonym: "lytic viral budding from ER membrane" EXACT [] +synonym: "lytic virus budding from ER membrane" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046758 +name: obsolete lytic virus budding from Golgi membrane +namespace: biological_process +def: "OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host Golgi membrane system, resulting in envelopment of the virus and cell lysis." [ISBN:0072370319] +comment: This term was made obsolete because it does not appear to correspond to a real biological process. +synonym: "lytic Golgi membrane viral budding" EXACT [] +synonym: "lytic viral budding from Golgi membrane" EXACT [] +synonym: "lytic virus budding from Golgi membrane" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046759 +name: obsolete lytic virus budding from plasma membrane +namespace: biological_process +def: "OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis." [ISBN:0072370319] +comment: This term was made obsolete because it does not appear to correspond to a real biological process. +synonym: "lytic plasma membrane viral budding" EXACT [] +synonym: "lytic viral budding from plasma membrane" EXACT [] +synonym: "lytic virus budding from plasma membrane" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046760 +name: viral budding from Golgi membrane +namespace: biological_process +alt_id: GO:0046750 +alt_id: GO:0046763 +def: "A viral budding that starts with formation of a membrane curvature in the host Golgi membrane." [GOC:bf, ISBN:0072370319, VZ:1947] +synonym: "Golgi membrane viral budding" EXACT [] +synonym: "Golgi membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from Golgi membrane by viral capsid envelopment" RELATED [] +synonym: "viral budding from Golgi membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from Golgi membrane" EXACT [] +synonym: "virus budding from Golgi membrane by viral capsid envelopment" RELATED [] +synonym: "virus budding from Golgi membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046755 ! viral budding + +[Term] +id: GO:0046761 +name: viral budding from plasma membrane +namespace: biological_process +alt_id: GO:0046766 +alt_id: GO:0046767 +def: "A viral budding that starts with formation of a membrane curvature in the host plasma membrane." [GOC:bf, ISBN:0072370319, PMID:9394621, VZ:1947] +synonym: "plasma membrane viral budding" EXACT [] +synonym: "plasma membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from plasma membrane by viral capsid envelopment" RELATED [] +synonym: "viral budding from plasma membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from plasma membrane" EXACT [] +synonym: "virus budding from plasma membrane by viral capsid envelopment" EXACT [] +synonym: "virus budding from plasma membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046753 ! non-lytic viral release +is_a: GO:0046755 ! viral budding + +[Term] +id: GO:0046762 +name: viral budding from endoplasmic reticulum membrane +namespace: biological_process +alt_id: GO:0046751 +alt_id: GO:0046764 +def: "A viral budding that starts with formation of a membrane curvature in the host ER membrane." [GOC:bf, GOC:jl, ISBN:0072370319, VZ:1947] +synonym: "endoplasmic reticulum membrane viral budding" EXACT [] +synonym: "endoplasmic reticulum membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "ER membrane viral budding" EXACT [] +synonym: "ER membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from ER membrane" EXACT [] +synonym: "viral budding from ER membrane by viral capsid envelopment" RELATED [] +synonym: "viral budding from ER membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from ER membrane" EXACT [] +synonym: "virus budding from ER membrane by viral capsid envelopment" EXACT [] +synonym: "virus budding from ER membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046755 ! viral budding + +[Term] +id: GO:0046765 +name: viral budding from nuclear membrane +namespace: biological_process +alt_id: GO:0046749 +def: "A viral budding that starts with formation of a membrane curvature in the host nuclear membrane." [GOC:bf, ISBN:0072370319] +synonym: "nuclear membrane viral budding" EXACT [] +synonym: "nuclear membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from nuclear membrane by viral capsid envelopment" RELATED [] +synonym: "viral budding from nuclear membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from nuclear membrane" EXACT [] +synonym: "virus budding from nuclear membrane by viral capsid envelopment" EXACT [] +synonym: "virus budding from nuclear membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046755 ! viral budding +relationship: part_of GO:0046802 ! exit of virus from host cell nucleus by nuclear egress + +[Term] +id: GO:0046771 +name: viral budding from inner nuclear membrane +namespace: biological_process +def: "The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope." [ISBN:0072370319] +synonym: "inner nuclear membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from inner nuclear membrane by viral capsid envelopment" RELATED [] +synonym: "viral budding from inner nuclear membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from inner nuclear membrane by viral capsid envelopment" EXACT [] +synonym: "virus budding from inner nuclear membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046765 ! viral budding from nuclear membrane + +[Term] +id: GO:0046772 +name: viral budding from outer nuclear membrane +namespace: biological_process +def: "The envelopment of a virus, in which the nucleocapsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope." [ISBN:0072370319] +synonym: "outer nuclear membrane viral budding during viral capsid envelopment" RELATED [] +synonym: "viral budding from outer nuclear membrane during viral capsid envelopment" RELATED [] +synonym: "virus budding from outer nuclear membrane by viral capsid envelopment" EXACT [] +synonym: "virus budding from outer nuclear membrane during viral capsid envelopment" RELATED [GOC:tb] +is_a: GO:0046765 ! viral budding from nuclear membrane + +[Term] +id: GO:0046773 +name: suppression by virus of host translation termination +namespace: biological_process +def: "Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA." [ISBN:0781718325] +synonym: "negative regulation by virus of host cell protein biosynthesis shutoff" EXACT [] +synonym: "negative regulation by virus of host cell protein biosynthetic process shutoff" EXACT [] +synonym: "suppression by virus of host termination of protein biosynthetic process" RELATED [] +synonym: "viral inhibition of host cell protein biosynthesis shutoff" EXACT [] +synonym: "viral inhibition of host cell protein biosynthetic process shutoff" EXACT [] +synonym: "viral inhibition of termination of host cell protein biosynthesis" EXACT [] +synonym: "viral inhibition of termination of host cell protein biosynthetic process" EXACT [] +synonym: "viral suppression of termination by host of host cell protein biosynthesis" EXACT [] +synonym: "viral suppression of termination by host of host cell protein biosynthetic process" EXACT [] +is_a: GO:0019057 ! modulation by virus of host translation + +[Term] +id: GO:0046774 +name: suppression by virus of host intracellular interferon activity +namespace: biological_process +def: "Any viral process that results in the inhibition of interferon activity within the host cell." [PMID:10859382] +synonym: "negative regulation by virus of intracellular interferon activity" EXACT [] +synonym: "suppression by virus of intracellular interferon activity in host" EXACT [] +is_a: GO:0030683 ! mitigation of host immune response by virus +is_a: GO:0075528 ! modulation by virus of host immune response + +[Term] +id: GO:0046775 +name: suppression by virus of host cytokine production +namespace: biological_process +def: "Any viral process that results in the inhibition of host cell cytokine production." [PMID:10859382] +synonym: "negative regulation by virus of host cytokine production" EXACT [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0044831 ! modulation by virus of host cytokine production +is_a: GO:0052562 ! suppression by symbiont of host immune response +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0001816 ! cytokine production + +[Term] +id: GO:0046776 +name: suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I +namespace: biological_process +def: "Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules." [GOC:add, GOC:bf, PMID:10859382, UniProtKB-KW:KW-1115, VZ:819] +synonym: "inhibition of host MHC class I molecule presentation by virus" EXACT [UniProtKB-KW:KW-1115] +synonym: "major histocompatibility complex" RELATED [] +synonym: "negative regulation by virus of MHC class I cell surface presentation" EXACT [] +synonym: "suppression by virus of host MHC class I cell surface presentation" EXACT [GOC:add] +synonym: "suppression by virus of MHC class I cell surface presentation in host" EXACT [] +xref: VZ:819 "Inhibition of host MHC class I molecule presentation by virus" +is_a: GO:0002590 ! negative regulation of antigen processing and presentation of peptide antigen via MHC class I +is_a: GO:0039588 ! suppression by virus of host antigen processing and presentation +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0002474 ! antigen processing and presentation of peptide antigen via MHC class I + +[Term] +id: GO:0046777 +name: protein autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)." [ISBN:0198506732] +synonym: "protein amino acid autophosphorylation" EXACT [GOC:bf] +xref: Wikipedia:Autophosphorylation +is_a: GO:0006468 ! protein phosphorylation + +[Term] +id: GO:0046778 +name: modification by virus of host mRNA processing +namespace: biological_process +def: "Any viral process that interferes with the processing of mRNA in the host cell." [ISBN:0781718325] +synonym: "viral perturbation of host mRNA processing" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0039656 ! modulation by virus of host gene expression +is_a: GO:0050684 ! regulation of mRNA processing + +[Term] +id: GO:0046779 +name: obsolete suppression by virus of expression of host genes with introns +namespace: biological_process +def: "OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed." [PMID:11598019] +comment: The reason for obsoleting this term is that it is too specific. +synonym: "negative regulation by virus of expression of host genes with introns" EXACT [] +synonym: "viral inhibition of expression of host genes with introns" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046780 +name: suppression by virus of host mRNA splicing +namespace: biological_process +alt_id: GO:0046781 +def: "Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production." [ISBN:0781718325, PMID:19729513] +synonym: "negative regulation by virus of host mRNA splicing" EXACT [] +synonym: "suppression by virus of host splicing factor activity" EXACT [] +synonym: "viral dispersion of host splicing factors" EXACT [] +synonym: "viral inhibition of host mRNA splicing" EXACT [] +is_a: GO:0033119 ! negative regulation of RNA splicing +is_a: GO:0039524 ! suppression by virus of host mRNA processing + +[Term] +id: GO:0046782 +name: regulation of viral transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the transcription of the viral genome." [GOC:ai] +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019083 ! viral transcription +relationship: regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0046783 +name: modification by virus of host polysomes +namespace: biological_process +def: "Any viral process that interferes with and inhibits the assembly and function of polysomes." [PMID:10438802] +comment: See also the cellular component term 'polysome ; GO:0005844'. +synonym: "viral perturbation of polysomes" EXACT [] +is_a: GO:0019057 ! modulation by virus of host translation + +[Term] +id: GO:0046784 +name: viral mRNA export from host cell nucleus +namespace: biological_process +def: "The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation." [PMID:11598019] +synonym: "intronless viral mRNA export from host cell nucleus" EXACT [] +synonym: "intronless viral mRNA export from host nucleus" RELATED [] +synonym: "intronless viral mRNA export out of nucleus" EXACT [] +synonym: "intronless viral mRNA transport from nucleus to cytoplasm" EXACT [] +synonym: "intronless viral mRNA-nucleus export" EXACT [] +is_a: GO:0044417 ! translocation of molecules into host + +[Term] +id: GO:0046785 +name: microtubule polymerization +namespace: biological_process +def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators] +synonym: "microtubule assembly" EXACT [] +synonym: "microtubule formation" RELATED [] +is_a: GO:0031109 ! microtubule polymerization or depolymerization +is_a: GO:0051258 ! protein polymerization +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0046786 +name: viral replication complex formation and maintenance +namespace: biological_process +def: "The process of organizing and assembling viral replication proteins in preparation for viral replication." [ISBN:0781718325] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019079 ! viral genome replication + +[Term] +id: GO:0046787 +name: viral DNA repair +namespace: biological_process +def: "The process of restoring viral DNA after damage or errors in replication." [ISBN:0781718325] +is_a: GO:0006281 ! DNA repair +relationship: part_of GO:0016032 ! viral process + +[Term] +id: GO:0046789 +name: host cell surface receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor on the host cell surface." [GOC:ai, PMID:11511370] +subset: goslim_chembl +synonym: "cell surface antigen activity, host-interacting" RELATED [] +synonym: "cell surface receptor ligand" RELATED [] +is_a: GO:0046812 ! host cell surface binding +relationship: part_of GO:0044650 ! adhesion of symbiont to host cell + +[Term] +id: GO:0046790 +name: virion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope." [GOC:ai] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0046791 +name: obsolete suppression by virus of host complement neutralization +namespace: biological_process +def: "OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell." [PMID:10587354] +comment: This term was made obsolete because the meaning of the term is unclear. It most likely refers to inhibiting the process by which a virus particle is neutralized by the host cell in a complement-dependent manner. +synonym: "negative regulation by virus of host complement neutralization" EXACT [] +synonym: "suppression by virus of host complement neutralization" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046792 +name: suppression by virus of host cell cycle arrest +namespace: biological_process +def: "Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur." [PMID:9371605] +synonym: "negative regulation by virus of cell cycle arrest" EXACT [] +synonym: "viral inhibition of cell cycle arrest" EXACT [] +is_a: GO:0019055 ! modification by virus of host cell cycle regulation + +[Term] +id: GO:0046793 +name: induction by virus of phosphorylation of host RNA polymerase II +namespace: biological_process +def: "Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II." [PMID:7637000] +synonym: "induction by virus of modification of host RNA polymerase II" BROAD [GOC:bf, GOC:jl] +synonym: "virus-induced modification of host RNA polymerase II" EXACT [] +is_a: GO:0019056 ! modulation by virus of host transcription +is_a: GO:0039614 ! induction by virus of host protein phosphorylation + +[Term] +id: GO:0046794 +name: transport of virus +namespace: biological_process +def: "The directed movement of a virus, or part of a virus, into, out of, or within a host cell." [GOC:ai] +subset: goslim_pir +synonym: "viral transport" EXACT [GOC:bf, GOC:jl] +synonym: "virion transport" NARROW [GOC:bf, GOC:jl] +is_a: GO:0016032 ! viral process +is_a: GO:0044766 ! multi-organism transport + +[Term] +id: GO:0046797 +name: viral procapsid maturation +namespace: biological_process +def: "The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure." [GOC:bf, PMID:10627558, PMID:19204733] +synonym: "capsid maturation" EXACT [] +synonym: "viral capsid maturation" EXACT [PMID:19204733] +synonym: "virion maturation" BROAD [UniProtKB-KW:KW-0917] +xref: UniProtKB-KW:KW-1273 +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0019069 ! viral capsid assembly +relationship: part_of GO:0019075 ! virus maturation + +[Term] +id: GO:0046798 +name: viral portal complex +namespace: cellular_component +def: "A multimeric ring of proteins through which the DNA enters and exits the viral capsid." [PMID:11602732] +is_a: GO:0032991 ! protein-containing complex +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019028 ! viral capsid + +[Term] +id: GO:0046799 +name: recruitment of helicase-primase complex to DNA lesions +namespace: biological_process +def: "The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair." [ISBN:0781718325] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0046787 ! viral DNA repair + +[Term] +id: GO:0046800 +name: obsolete enhancement of virulence +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease." [PMID:10587354] +comment: This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism. +synonym: "enhancement of virulence" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046802 +name: exit of virus from host cell nucleus by nuclear egress +namespace: biological_process +alt_id: GO:0039676 +def: "The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm." [PMID:21494278, PMID:22858153, PMID:9601512, PMID:9765421, VZ:1952] +synonym: "capsid egress" EXACT [VZ:2177] +synonym: "egress of viral procapsid from host cell nucleus" RELATED [] +synonym: "nuclear egress" EXACT [PMID:22858153] +synonym: "nuclear egress of viral procapsid" EXACT [] +xref: VZ:1952 "Nuclear egress" +is_a: GO:0039674 ! exit of virus from host cell nucleus + +[Term] +id: GO:0046803 +name: obsolete reduction of virulence +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease." [PMID:10982346] +comment: This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism. +synonym: "reduction of virulence" EXACT [] +is_obsolete: true + +[Term] +id: GO:0046804 +name: peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide +namespace: biological_process +def: "The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine." [RESID:AA0330] +synonym: "peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide" EXACT [] +xref: RESID:AA0330 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0046805 +name: protein-heme linkage via 1'-L-histidine +namespace: biological_process +def: "The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine)." [RESID:AA0329] +synonym: "protein-haem linkage via 1'-L-histidine" EXACT [] +xref: RESID:AA0329 +is_a: GO:0017003 ! protein-heme linkage +is_a: GO:0017004 ! cytochrome complex assembly + +[Term] +id: GO:0046806 +name: viral scaffold +namespace: cellular_component +def: "A complex of proteins that form a scaffold around which the viral capsid is constructed." [ISBN:0072370319] +is_a: GO:0032991 ! protein-containing complex +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019028 ! viral capsid + +[Term] +id: GO:0046807 +name: viral scaffold assembly and maintenance +namespace: biological_process +def: "The assembly and maintenance of the viral scaffold around which the viral capsid is constructed." [ISBN:0072370319] +comment: See also the cellular component term 'viral scaffold ; GO:0046806'. +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019069 ! viral capsid assembly + +[Term] +id: GO:0046808 +name: assemblon +namespace: cellular_component +def: "Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously." [PMID:8676489] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0046809 +name: replication compartment +namespace: cellular_component +def: "Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously." [PMID:9499108, VZ:1951] +synonym: "RC" EXACT [VZ:1951] +is_a: GO:0039715 ! nuclear viral factory + +[Term] +id: GO:0046810 +name: host cell extracellular matrix binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the extracellular matrix of a host cell." [PMID:7996163] +is_a: GO:0050840 ! extracellular matrix binding + +[Term] +id: GO:0046811 +name: histone deacetylase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes." [GOC:ai, PMID:10482575] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0035033 ! histone deacetylase regulator activity +relationship: negatively_regulates GO:0004407 ! histone deacetylase activity +relationship: part_of GO:0031064 ! negative regulation of histone deacetylation + +[Term] +id: GO:0046812 +name: host cell surface binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the surface of a host cell." [GOC:ai] +subset: goslim_pir +is_a: GO:0005488 ! binding +relationship: part_of GO:0044764 ! multi-organism cellular process + +[Term] +id: GO:0046813 +name: receptor-mediated virion attachment to host cell +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface." [ISBN:0879694971] +synonym: "virion attachment, binding of host cell surface receptor" EXACT [GOC:bf, GOC:jl] +is_a: GO:0019062 ! virion attachment to host cell +relationship: has_part GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0046814 +name: coreceptor-mediated virion attachment to host cell +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface." [ISBN:0879694971] +synonym: "virion attachment, binding of host cell surface coreceptor" EXACT [GOC:bf, GOC:jl] +is_a: GO:0019062 ! virion attachment to host cell +relationship: has_part GO:0039706 ! co-receptor binding + +[Term] +id: GO:0046815 +name: genome retention in viral capsid +namespace: biological_process +def: "Any process in which the viral genome is retained within the capsid during genome cleavage and packaging." [PMID:9696839] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019079 ! viral genome replication + +[Term] +id: GO:0046816 +name: virion transport vesicle +namespace: cellular_component +def: "A vesicle used to transport the partial or complete virion between cellular compartments." [GOC:vesicles, PMID:7933124] +is_a: GO:0097708 ! intracellular vesicle + +[Term] +id: GO:0046817 +name: chemokine receptor antagonist activity +namespace: molecular_function +def: "Interacts with chemokine receptors to reduce the action of a chemokine." [GOC:ai, ISBN:0781718325] +is_a: GO:0048019 ! receptor antagonist activity +relationship: part_of GO:0070100 ! negative regulation of chemokine-mediated signaling pathway + +[Term] +id: GO:0046818 +name: dense nuclear body +namespace: cellular_component +def: "A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously." [PMID:10233976] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0046819 +name: protein secretion by the type V secretion system +namespace: biological_process +def: "The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway." [GOC:pamgo_curators] +synonym: "autotransporter system" EXACT [] +synonym: "protein secretion by the autotransporter system" EXACT [] +synonym: "protein secretion by the type V protein secretion system" EXACT [] +synonym: "type V protein secretion system" EXACT [] +is_a: GO:0009306 ! protein secretion +is_a: GO:0098776 ! protein transport across the cell outer membrane + +[Term] +id: GO:0046820 +name: 4-amino-4-deoxychorismate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate." [EC:2.6.1.85, RHEA:11672] +comment: Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate. +synonym: "ADC synthase activity" EXACT [EC:2.6.1.85] +synonym: "aminodeoxychorismate synthase activity" RELATED [] +synonym: "chorismate:L-glutamine amido-ligase activity" EXACT [EC:2.6.1.85] +synonym: "p-aminobenzoate synthetase" RELATED [] +synonym: "PabB activity" RELATED [EC:2.6.1.85] +synonym: "para-aminobenzoic acid (PABA) synthase" RELATED [] +synonym: "para-aminobenzoic acid synthase activity" RELATED [] +xref: EC:2.6.1.85 +xref: KEGG_REACTION:R01716 +xref: MetaCyc:PABASYN-RXN +xref: RHEA:11672 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0046821 +name: extrachromosomal DNA +namespace: cellular_component +def: "DNA structures that are not part of a chromosome." [GOC:ai] +xref: Wikipedia:Extrachromosomal_DNA +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0046822 +name: regulation of nucleocytoplasmic transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." [GOC:bf] +is_a: GO:0032386 ! regulation of intracellular transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006913 ! nucleocytoplasmic transport +relationship: regulates GO:0006913 ! nucleocytoplasmic transport + +[Term] +id: GO:0046823 +name: negative regulation of nucleocytoplasmic transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." [GOC:bf] +synonym: "down regulation of nucleocytoplasmic transport" EXACT [] +synonym: "down-regulation of nucleocytoplasmic transport" EXACT [] +synonym: "downregulation of nucleocytoplasmic transport" EXACT [] +synonym: "inhibition of nucleocytoplasmic transport" NARROW [] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006913 ! nucleocytoplasmic transport +relationship: negatively_regulates GO:0006913 ! nucleocytoplasmic transport + +[Term] +id: GO:0046824 +name: positive regulation of nucleocytoplasmic transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." [GOC:bf] +synonym: "activation of nucleocytoplasmic transport" NARROW [] +synonym: "stimulation of nucleocytoplasmic transport" NARROW [] +synonym: "up regulation of nucleocytoplasmic transport" EXACT [] +synonym: "up-regulation of nucleocytoplasmic transport" EXACT [] +synonym: "upregulation of nucleocytoplasmic transport" EXACT [] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006913 ! nucleocytoplasmic transport +relationship: positively_regulates GO:0006913 ! nucleocytoplasmic transport + +[Term] +id: GO:0046825 +name: regulation of protein export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." [GOC:bf] +synonym: "regulation of protein export from cell nucleus" EXACT [] +synonym: "regulation of protein export out of nucleus" EXACT [] +synonym: "regulation of protein transport from nucleus to cytoplasm" EXACT [] +synonym: "regulation of protein-nucleus export" EXACT [] +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006611 ! protein export from nucleus +relationship: regulates GO:0006611 ! protein export from nucleus + +[Term] +id: GO:0046826 +name: negative regulation of protein export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." [GOC:bf] +synonym: "down regulation of protein export from nucleus" EXACT [] +synonym: "down-regulation of protein export from nucleus" EXACT [] +synonym: "downregulation of protein export from nucleus" EXACT [] +synonym: "inhibition of protein export from nucleus" NARROW [] +synonym: "negative regulation of protein export from cell nucleus" EXACT [] +synonym: "negative regulation of protein export out of nucleus" EXACT [] +synonym: "negative regulation of protein transport from nucleus to cytoplasm" EXACT [] +synonym: "negative regulation of protein-nucleus export" EXACT [] +is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport +is_a: GO:0046825 ! regulation of protein export from nucleus +is_a: GO:0051457 ! maintenance of protein location in nucleus +is_a: GO:0090317 ! negative regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006611 ! protein export from nucleus +relationship: negatively_regulates GO:0006611 ! protein export from nucleus + +[Term] +id: GO:0046827 +name: positive regulation of protein export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." [GOC:bf] +synonym: "activation of protein export from nucleus" NARROW [] +synonym: "positive regulation of protein export from cell nucleus" EXACT [] +synonym: "positive regulation of protein export out of nucleus" EXACT [] +synonym: "positive regulation of protein transport from nucleus to cytoplasm" EXACT [] +synonym: "positive regulation of protein-nucleus export" EXACT [] +synonym: "stimulation of protein export from nucleus" NARROW [] +synonym: "up regulation of protein export from nucleus" EXACT [] +synonym: "up-regulation of protein export from nucleus" EXACT [] +synonym: "upregulation of protein export from nucleus" EXACT [] +is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport +is_a: GO:0046825 ! regulation of protein export from nucleus +is_a: GO:0090316 ! positive regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006611 ! protein export from nucleus +relationship: positively_regulates GO:0006611 ! protein export from nucleus + +[Term] +id: GO:0046828 +name: regulation of RNA import into nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus." [GOC:bf] +synonym: "regulation of RNA import into cell nucleus" EXACT [] +synonym: "regulation of RNA transport from cytoplasm to nucleus" EXACT [] +synonym: "regulation of RNA-nucleus import" EXACT [] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006404 ! RNA import into nucleus +relationship: regulates GO:0006404 ! RNA import into nucleus + +[Term] +id: GO:0046829 +name: negative regulation of RNA import into nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus." [GOC:bf] +synonym: "down regulation of RNA import into nucleus" EXACT [] +synonym: "down-regulation of RNA import into nucleus" EXACT [] +synonym: "downregulation of RNA import into nucleus" EXACT [] +synonym: "inhibition of RNA import into nucleus" NARROW [] +synonym: "negative regulation of RNA import into cell nucleus" EXACT [] +synonym: "negative regulation of RNA transport from cytoplasm to nucleus" EXACT [] +synonym: "negative regulation of RNA-nucleus import" EXACT [] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport +is_a: GO:0046828 ! regulation of RNA import into nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006404 ! RNA import into nucleus +relationship: negatively_regulates GO:0006404 ! RNA import into nucleus + +[Term] +id: GO:0046830 +name: positive regulation of RNA import into nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus." [GOC:bf] +synonym: "activation of RNA import into nucleus" NARROW [] +synonym: "positive regulation of RNA import into cell nucleus" EXACT [] +synonym: "positive regulation of RNA transport from cytoplasm to nucleus" EXACT [] +synonym: "positive regulation of RNA-nucleus import" EXACT [] +synonym: "stimulation of RNA import into nucleus" NARROW [] +synonym: "up regulation of RNA import into nucleus" EXACT [] +synonym: "up-regulation of RNA import into nucleus" EXACT [] +synonym: "upregulation of RNA import into nucleus" EXACT [] +is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport +is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport +is_a: GO:0046828 ! regulation of RNA import into nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006404 ! RNA import into nucleus +relationship: positively_regulates GO:0006404 ! RNA import into nucleus + +[Term] +id: GO:0046831 +name: regulation of RNA export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." [GOC:bf] +synonym: "regulation of RNA export from cell nucleus" EXACT [] +synonym: "regulation of RNA export out of nucleus" EXACT [] +synonym: "regulation of RNA transport from nucleus to cytoplasm" EXACT [] +synonym: "regulation of RNA-nucleus export" EXACT [] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +is_a: GO:0046822 ! regulation of nucleocytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006405 ! RNA export from nucleus +relationship: regulates GO:0006405 ! RNA export from nucleus + +[Term] +id: GO:0046832 +name: negative regulation of RNA export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." [GOC:bf] +synonym: "down regulation of RNA export from nucleus" EXACT [] +synonym: "down-regulation of RNA export from nucleus" EXACT [] +synonym: "downregulation of RNA export from nucleus" EXACT [] +synonym: "inhibition of RNA export from nucleus" NARROW [] +synonym: "negative regulation of RNA export from cell nucleus" EXACT [] +synonym: "negative regulation of RNA export out of nucleus" EXACT [] +synonym: "negative regulation of RNA transport from nucleus to cytoplasm" EXACT [] +synonym: "negative regulation of RNA-nucleus export" EXACT [] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0046823 ! negative regulation of nucleocytoplasmic transport +is_a: GO:0046831 ! regulation of RNA export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006405 ! RNA export from nucleus +relationship: negatively_regulates GO:0006405 ! RNA export from nucleus + +[Term] +id: GO:0046833 +name: positive regulation of RNA export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." [GOC:bf] +synonym: "activation of RNA export from nucleus" NARROW [] +synonym: "positive regulation of RNA export from cell nucleus" EXACT [] +synonym: "positive regulation of RNA export out of nucleus" EXACT [] +synonym: "positive regulation of RNA transport from nucleus to cytoplasm" EXACT [] +synonym: "positive regulation of RNA-nucleus export" EXACT [] +synonym: "stimulation of RNA export from nucleus" NARROW [] +synonym: "up regulation of RNA export from nucleus" EXACT [] +synonym: "up-regulation of RNA export from nucleus" EXACT [] +synonym: "upregulation of RNA export from nucleus" EXACT [] +is_a: GO:0032241 ! positive regulation of nucleobase-containing compound transport +is_a: GO:0046824 ! positive regulation of nucleocytoplasmic transport +is_a: GO:0046831 ! regulation of RNA export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006405 ! RNA export from nucleus +relationship: positively_regulates GO:0006405 ! RNA export from nucleus + +[Term] +id: GO:0046834 +name: lipid phosphorylation +namespace: biological_process +def: "The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents." [GOC:bf, ISBN:0198506732] +is_a: GO:0016310 ! phosphorylation +is_a: GO:0030258 ! lipid modification + +[Term] +id: GO:0046835 +name: carbohydrate phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y." [ISBN:0198506732] +is_a: GO:0016310 ! phosphorylation +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0046836 +name: glycolipid transport +namespace: biological_process +def: "The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0006869 ! lipid transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0046838 +name: phosphorylated carbohydrate dephosphorylation +namespace: biological_process +def: "The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it." [ISBN:0198506732] +is_a: GO:0016311 ! dephosphorylation +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0046839 +name: phospholipid dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents." [ISBN:0198506732] +is_a: GO:0016311 ! dephosphorylation +is_a: GO:0030258 ! lipid modification + +[Term] +id: GO:0046841 +name: trisporic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota." [GOC:ai] +synonym: "trisporic acid metabolism" EXACT [] +is_a: GO:0019752 ! carboxylic acid metabolic process + +[Term] +id: GO:0046842 +name: trisporic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trisporic acid." [GOC:ai] +synonym: "trisporic acid anabolism" EXACT [] +synonym: "trisporic acid biosynthesis" EXACT [] +synonym: "trisporic acid formation" EXACT [] +synonym: "trisporic acid synthesis" EXACT [] +is_a: GO:0046841 ! trisporic acid metabolic process + +[Term] +id: GO:0046843 +name: dorsal appendage formation +namespace: biological_process +def: "Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration." [ISBN:0879694238] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007306 ! eggshell chorion assembly + +[Term] +id: GO:0046844 +name: chorion micropyle formation +namespace: biological_process +def: "Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization." [ISBN:0879694238] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007306 ! eggshell chorion assembly + +[Term] +id: GO:0046845 +name: branched duct epithelial cell fate determination, open tracheal system +namespace: biological_process +def: "Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode." [GOC:mtg_sensu, PMID:10684581] +synonym: "branch cell fate determination" BROAD [] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0046847 +name: filopodium assembly +namespace: biological_process +def: "The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:dph, GOC:mah, GOC:tb, PMID:16337369, PMID:18464790] +synonym: "filopodia biosynthesis" RELATED [] +synonym: "filopodia formation" RELATED [] +synonym: "filopodium formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly + +[Term] +id: GO:0046848 +name: hydroxyapatite binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin." [PMID:2438276] +synonym: "hydroxylapatite binding" EXACT [GOC:vk] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0046849 +name: bone remodeling +namespace: biological_process +def: "The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis." [GOC:curators] +synonym: "bone remodelling" EXACT [] +xref: Wikipedia:Bone_remodeling +is_a: GO:0048771 ! tissue remodeling + +[Term] +id: GO:0046850 +name: regulation of bone remodeling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity." [GOC:ai] +is_a: GO:0034103 ! regulation of tissue remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046849 ! bone remodeling +relationship: regulates GO:0046849 ! bone remodeling + +[Term] +id: GO:0046851 +name: negative regulation of bone remodeling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling." [GOC:ai] +synonym: "down regulation of bone remodeling" EXACT [] +synonym: "down-regulation of bone remodeling" EXACT [] +synonym: "downregulation of bone remodeling" EXACT [] +synonym: "inhibition of bone remodeling" NARROW [] +is_a: GO:0034104 ! negative regulation of tissue remodeling +is_a: GO:0046850 ! regulation of bone remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046849 ! bone remodeling +relationship: negatively_regulates GO:0046849 ! bone remodeling + +[Term] +id: GO:0046852 +name: positive regulation of bone remodeling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone remodeling." [GOC:ai] +synonym: "activation of bone remodeling" NARROW [] +synonym: "stimulation of bone remodeling" NARROW [] +synonym: "up regulation of bone remodeling" EXACT [] +synonym: "up-regulation of bone remodeling" EXACT [] +synonym: "upregulation of bone remodeling" EXACT [] +is_a: GO:0034105 ! positive regulation of tissue remodeling +is_a: GO:0046850 ! regulation of bone remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046849 ! bone remodeling +relationship: positively_regulates GO:0046849 ! bone remodeling + +[Term] +id: GO:0046853 +name: obsolete inositol or phosphatidylinositol phosphorylation +namespace: biological_process +def: "OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms." [ISBN:0198506732] +comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. +synonym: "inositol and derivative phosphorylation" RELATED [] +synonym: "inositol or phosphatidylinositol phosphorylation" EXACT [] +synonym: "myo-inositol and derivative phosphorylation" RELATED [] +synonym: "myo-inositol or phosphatidyl-myo-inositol phosphorylation" NARROW [] +is_obsolete: true +consider: GO:0046854 +consider: GO:0052746 + +[Term] +id: GO:0046854 +name: phosphatidylinositol phosphorylation +namespace: biological_process +alt_id: GO:0046837 +def: "The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol." [ISBN:0198506732] +synonym: "phosphatidylinositol phosphate biosynthetic process" NARROW [] +synonym: "phosphatidylinositol phosphate phosphorylation" NARROW [] +synonym: "phosphoinositide phosphorylation" NARROW [] +synonym: "PIP biosynthesis" NARROW [] +synonym: "PtdInsP biosynthesis" NARROW [] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +is_a: GO:0046834 ! lipid phosphorylation + +[Term] +id: GO:0046855 +name: inositol phosphate dephosphorylation +namespace: biological_process +def: "The process of removing a phosphate group from any mono- or polyphosphorylated inositol." [ISBN:0198506732] +synonym: "myo-inositol phosphate dephosphorylation" NARROW [] +is_a: GO:0046838 ! phosphorylated carbohydrate dephosphorylation +is_a: GO:0071545 ! inositol phosphate catabolic process + +[Term] +id: GO:0046856 +name: phosphatidylinositol dephosphorylation +namespace: biological_process +alt_id: GO:0046840 +def: "The process of removing one or more phosphate groups from a phosphatidylinositol." [ISBN:0198506732] +synonym: "phosphatidylinositol phosphate catabolic process" NARROW [] +synonym: "phosphatidylinositol phosphate dephosphorylation" NARROW [] +synonym: "phosphoinositide dephosphorylation" EXACT [] +synonym: "PIP catabolism" NARROW [] +synonym: "PtdInsP catabolism" NARROW [] +synonym: "PtdInsP dephosphorylation" NARROW [] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +is_a: GO:0046839 ! phospholipid dephosphorylation + +[Term] +id: GO:0046857 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] +xref: EC:1.7.1 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0046858 +name: chlorosome +namespace: cellular_component +def: "A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate." [ISBN:0198506732, PMID:14729689, PMID:15298919] +xref: Wikipedia:Chlorosome +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle + +[Term] +id: GO:0046859 +name: hydrogenosomal membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a hydrogenosome." [GOC:ai] +synonym: "hydrogenosome membrane" EXACT [] +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0042566 ! hydrogenosome + +[Term] +id: GO:0046860 +name: glycosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a glycosome." [GOC:ai] +is_a: GO:0005778 ! peroxisomal membrane +relationship: part_of GO:0020015 ! glycosome + +[Term] +id: GO:0046861 +name: glyoxysomal membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a glyoxysome." [GOC:ai] +synonym: "glyoxysome membrane" EXACT [] +is_a: GO:0005778 ! peroxisomal membrane + +[Term] +id: GO:0046862 +name: chromoplast membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope." [GOC:ai, GOC:mah] +is_a: GO:0042170 ! plastid membrane +relationship: part_of GO:0031898 ! chromoplast envelope + +[Term] +id: GO:0046863 +name: ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity +namespace: molecular_function +alt_id: GO:0018236 +def: "Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate." [PMID:10430961, PMID:10965036, PMID:2404515] +comment: See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'. +synonym: "ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity" EXACT [GOC:dph, GOC:tb] +synonym: "ribulose-bisphosphate carboxylase activase activity" EXACT [] +synonym: "rubisco activase activity" EXACT [] +synonym: "rubisco activator" EXACT [] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0016984 ! ribulose-bisphosphate carboxylase activity + +[Term] +id: GO:0046864 +name: isoprenoid transport +namespace: biological_process +def: "The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [GOC:ai] +subset: goslim_pir +is_a: GO:0006869 ! lipid transport + +[Term] +id: GO:0046865 +name: terpenoid transport +namespace: biological_process +def: "The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups." [GOC:ai] +is_a: GO:0046864 ! isoprenoid transport + +[Term] +id: GO:0046866 +name: tetraterpenoid transport +namespace: biological_process +def: "The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units." [GOC:ai] +is_a: GO:0046865 ! terpenoid transport + +[Term] +id: GO:0046867 +name: carotenoid transport +namespace: biological_process +def: "The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail." [GOC:ai] +is_a: GO:0046866 ! tetraterpenoid transport + +[Term] +id: GO:0046868 +name: mesosome +namespace: cellular_component +def: "An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins." [ISBN:0198506732, ISBN:0716731363] +xref: Wikipedia:Mesosome +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0046869 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide +namespace: biological_process +def: "The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide." [RESID:AA0331] +synonym: "iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato diiron disulphide" EXACT [] +xref: RESID:AA0331 +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0046870 +name: cadmium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cadmium (Cd) ions." [GOC:ai] +synonym: "cadmium binding" EXACT [] +synonym: "copper/cadmium binding" BROAD [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0046871 +name: N-acetylgalactosamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine." [GOC:ai, PMID:18384150] +synonym: "N-acetylgalactosamine lectin" RELATED [] +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0046872 +name: metal ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any metal ion." [GOC:ai] +subset: goslim_agr +subset: goslim_drosophila +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +synonym: "heavy metal binding" NARROW [] +synonym: "metal binding" EXACT [] +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0046873 +name: metal ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] +synonym: "heavy metal ion porter activity" NARROW [] +synonym: "heavy metal ion transporter activity" NARROW [] +synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] +synonym: "heavy metal-exporting ATPase activity" NARROW [] +synonym: "high affinity metal ion uptake transporter activity" NARROW [] +synonym: "low affinity metal ion uptake transporter activity" NARROW [] +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity +relationship: part_of GO:0030001 ! metal ion transport + +[Term] +id: GO:0046874 +name: quinolinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid." [GOC:ai] +synonym: "quinolinate metabolism" EXACT [] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process + +[Term] +id: GO:0046875 +name: ephrin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an ephrin receptor." [GOC:ai] +synonym: "Eph receptor binding" EXACT [] +synonym: "ephrin" NARROW [] +synonym: "GPI-linked ephrin" NARROW [] +synonym: "transmembrane ephrin" NARROW [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0046876 +name: 3,4-didehydroretinal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod)." [GOC:ai, ISBN:0198506732] +synonym: "blue-sensitive opsin" NARROW [] +synonym: "green-sensitive opsin" NARROW [] +synonym: "long-wave-sensitive opsin" NARROW [] +synonym: "opsin" NARROW [] +synonym: "red-sensitive opsin" NARROW [] +synonym: "short-wave-sensitive opsin" NARROW [] +synonym: "UV-sensitive opsin" NARROW [] +synonym: "violet-sensitive opsin" NARROW [] +is_a: GO:0005501 ! retinoid binding + +[Term] +id: GO:0046877 +name: regulation of saliva secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue." [GOC:ai] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0050878 ! regulation of body fluid levels +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046541 ! saliva secretion +relationship: regulates GO:0046541 ! saliva secretion + +[Term] +id: GO:0046878 +name: positive regulation of saliva secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of saliva." [GOC:ai] +synonym: "activation of saliva secretion" NARROW [] +synonym: "stimulation of saliva secretion" NARROW [] +synonym: "up regulation of saliva secretion" EXACT [] +synonym: "up-regulation of saliva secretion" EXACT [] +synonym: "upregulation of saliva secretion" EXACT [] +is_a: GO:0046877 ! regulation of saliva secretion +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0060456 ! positive regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046541 ! saliva secretion +relationship: positively_regulates GO:0046541 ! saliva secretion + +[Term] +id: GO:0046879 +name: hormone secretion +namespace: biological_process +def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] +is_a: GO:0009914 ! hormone transport +is_a: GO:0023061 ! signal release + +[Term] +id: GO:0046880 +name: regulation of follicle-stimulating hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] +synonym: "regulation of follicle stimulating hormone secretion" EXACT [] +synonym: "regulation of FSH secretion" EXACT [] +is_a: GO:0032276 ! regulation of gonadotropin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046884 ! follicle-stimulating hormone secretion +relationship: regulates GO:0046884 ! follicle-stimulating hormone secretion + +[Term] +id: GO:0046881 +name: positive regulation of follicle-stimulating hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] +synonym: "activation of follicle-stimulating hormone secretion" NARROW [] +synonym: "positive regulation of follicle stimulating hormone secretion" EXACT [] +synonym: "stimulation of follicle-stimulating hormone secretion" NARROW [] +synonym: "up regulation of follicle-stimulating hormone secretion" EXACT [] +synonym: "up-regulation of follicle-stimulating hormone secretion" EXACT [] +synonym: "upregulation of follicle-stimulating hormone secretion" EXACT [] +is_a: GO:0032278 ! positive regulation of gonadotropin secretion +is_a: GO:0046880 ! regulation of follicle-stimulating hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046884 ! follicle-stimulating hormone secretion +relationship: positively_regulates GO:0046884 ! follicle-stimulating hormone secretion + +[Term] +id: GO:0046882 +name: negative regulation of follicle-stimulating hormone secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] +synonym: "down regulation of follicle-stimulating hormone secretion" EXACT [] +synonym: "down-regulation of follicle-stimulating hormone secretion" EXACT [] +synonym: "downregulation of follicle-stimulating hormone secretion" EXACT [] +synonym: "inhibition of follicle-stimulating hormone secretion" NARROW [] +synonym: "negative regulation of follicle stimulating hormone secretion" EXACT [] +is_a: GO:0032277 ! negative regulation of gonadotropin secretion +is_a: GO:0046880 ! regulation of follicle-stimulating hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046884 ! follicle-stimulating hormone secretion +relationship: negatively_regulates GO:0046884 ! follicle-stimulating hormone secretion + +[Term] +id: GO:0046883 +name: regulation of hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0010817 ! regulation of hormone levels +is_a: GO:0023051 ! regulation of signaling +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046879 ! hormone secretion +relationship: regulates GO:0046879 ! hormone secretion + +[Term] +id: GO:0046884 +name: follicle-stimulating hormone secretion +namespace: biological_process +def: "The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary." [ISBN:0198506732] +synonym: "follicle stimulating hormone secretion" EXACT [] +synonym: "follitropin secretion" EXACT [] +synonym: "FSH secretion" EXACT [] +is_a: GO:0032274 ! gonadotropin secretion + +[Term] +id: GO:0046885 +name: regulation of hormone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] +synonym: "regulation of hormone anabolism" EXACT [] +synonym: "regulation of hormone biosynthesis" EXACT [] +synonym: "regulation of hormone formation" EXACT [] +synonym: "regulation of hormone synthesis" EXACT [] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042446 ! hormone biosynthetic process +relationship: regulates GO:0042446 ! hormone biosynthetic process + +[Term] +id: GO:0046886 +name: positive regulation of hormone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] +synonym: "activation of hormone biosynthetic process" NARROW [] +synonym: "positive regulation of hormone anabolism" EXACT [] +synonym: "positive regulation of hormone biosynthesis" EXACT [] +synonym: "positive regulation of hormone formation" EXACT [] +synonym: "positive regulation of hormone synthesis" EXACT [] +synonym: "stimulation of hormone biosynthetic process" NARROW [] +synonym: "up regulation of hormone biosynthetic process" EXACT [] +synonym: "up-regulation of hormone biosynthetic process" EXACT [] +synonym: "upregulation of hormone biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042446 ! hormone biosynthetic process +relationship: positively_regulates GO:0042446 ! hormone biosynthetic process + +[Term] +id: GO:0046887 +name: positive regulation of hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] +synonym: "activation of hormone secretion" NARROW [] +synonym: "stimulation of hormone secretion" NARROW [] +synonym: "up regulation of hormone secretion" EXACT [] +synonym: "up-regulation of hormone secretion" EXACT [] +synonym: "upregulation of hormone secretion" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0046883 ! regulation of hormone secretion +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046879 ! hormone secretion +relationship: positively_regulates GO:0046879 ! hormone secretion + +[Term] +id: GO:0046888 +name: negative regulation of hormone secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] +synonym: "down regulation of hormone secretion" EXACT [] +synonym: "down-regulation of hormone secretion" EXACT [] +synonym: "downregulation of hormone secretion" EXACT [] +synonym: "inhibition of hormone secretion" NARROW [] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0046883 ! regulation of hormone secretion +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046879 ! hormone secretion +relationship: negatively_regulates GO:0046879 ! hormone secretion + +[Term] +id: GO:0046889 +name: positive regulation of lipid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] +synonym: "activation of lipid biosynthetic process" NARROW [] +synonym: "positive regulation of lipid anabolism" EXACT [] +synonym: "positive regulation of lipid biosynthesis" EXACT [] +synonym: "positive regulation of lipid formation" EXACT [] +synonym: "positive regulation of lipid synthesis" EXACT [] +synonym: "positive regulation of lipogenesis" EXACT [GOC:sl] +synonym: "stimulation of lipid biosynthetic process" NARROW [] +synonym: "up regulation of lipid biosynthetic process" EXACT [] +synonym: "up-regulation of lipid biosynthetic process" EXACT [] +synonym: "upregulation of lipid biosynthetic process" EXACT [] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008610 ! lipid biosynthetic process +relationship: positively_regulates GO:0008610 ! lipid biosynthetic process + +[Term] +id: GO:0046890 +name: regulation of lipid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] +synonym: "regulation of lipid anabolism" EXACT [] +synonym: "regulation of lipid biosynthesis" EXACT [] +synonym: "regulation of lipid formation" EXACT [] +synonym: "regulation of lipid synthesis" EXACT [] +synonym: "regulation of lipogenesis" EXACT [GOC:sl] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008610 ! lipid biosynthetic process +relationship: regulates GO:0008610 ! lipid biosynthetic process + +[Term] +id: GO:0046891 +name: peptidyl-cysteine S-carbamoylation +namespace: biological_process +def: "The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine." [RESID:AA0332] +xref: RESID:AA0332 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0046892 +name: peptidyl-S-carbamoyl-L-cysteine dehydration +namespace: biological_process +def: "The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine." [PMID:12586941, RESID:AA0333] +synonym: "formation of peptidyl-S-cyanocysteine" EXACT [] +synonym: "formation of peptidyl-serine thiocyanate ester" EXACT [] +xref: RESID:AA0333 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018249 ! protein dehydration + +[Term] +id: GO:0046893 +name: iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation +namespace: biological_process +def: "The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase." [RESID:AA0334] +xref: RESID:AA0334 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0046894 +name: enzyme active site formation via S-amidino-L-cysteine +namespace: biological_process +def: "Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine." [RESID:AA0335] +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0098823 ! peptidyl-cysteine modification to S-amindino-L-cysteine + +[Term] +id: GO:0046895 +name: N-terminal peptidyl-isoleucine methylation +namespace: biological_process +def: "The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine." [RESID:AA0336] +xref: RESID:AA0336 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018203 ! peptidyl-isoleucine modification + +[Term] +id: GO:0046896 +name: N-terminal peptidyl-leucine methylation +namespace: biological_process +def: "The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine." [RESID:AA0337] +xref: RESID:AA0337 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018204 ! peptidyl-leucine modification + +[Term] +id: GO:0046897 +name: N-terminal peptidyl-tyrosine methylation +namespace: biological_process +def: "The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine." [RESID:AA0338] +xref: RESID:AA0338 +is_a: GO:0006480 ! N-terminal protein amino acid methylation +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0046898 +name: response to cycloheximide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes." [GOC:ef, ISBN:0198506732] +synonym: "response to actidione" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0060992 ! response to fungicide +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0046899 +name: nucleoside triphosphate adenylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP." [EC:2.7.4.10] +synonym: "GTP:AMP phosphotransferase" NARROW [] +synonym: "guanosine triphosphate-adenylate kinase" NARROW [] +synonym: "isozyme 3 of adenylate kinase activity" EXACT [EC:2.7.4.10] +synonym: "nucleoside triphosphate-adenosine monophosphate transphosphorylase activity" EXACT [] +synonym: "nucleoside-triphosphate-adenylate kinase activity" EXACT [] +synonym: "nucleoside-triphosphate:AMP phosphotransferase activity" EXACT [EC:2.7.4.10] +xref: EC:2.7.4.10 +xref: MetaCyc:2.7.4.10-RXN +xref: Reactome:R-HSA-1008248 "Adenylate Kinase 3 is a GTP-AMP phosphotransferase" +xref: RHEA:13749 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity + +[Term] +id: GO:0046900 +name: tetrahydrofolylpolyglutamate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues." [GOC:ai] +synonym: "tetrahydrofolyl-[Glu](n) metabolic process" EXACT [] +synonym: "tetrahydrofolyl-[Glu](n) metabolism" EXACT [] +synonym: "tetrahydrofolylpolyglutamate metabolism" EXACT [] +is_a: GO:0006760 ! folic acid-containing compound metabolic process + +[Term] +id: GO:0046901 +name: tetrahydrofolylpolyglutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues." [GOC:ai] +synonym: "folic acid-containing compound polyglutamylation" BROAD [GOC:dhl] +synonym: "tetrahydrofolate polyglutamylation" EXACT [GOC:bf, KEGG:ec00790] +synonym: "tetrahydrofolyl-[Glu](n) biosynthesis" EXACT [] +synonym: "tetrahydrofolyl-[Glu](n) biosynthetic process" EXACT [] +synonym: "tetrahydrofolylpolyglutamate anabolism" EXACT [] +synonym: "tetrahydrofolylpolyglutamate biosynthesis" EXACT [] +synonym: "tetrahydrofolylpolyglutamate formation" EXACT [] +synonym: "tetrahydrofolylpolyglutamate synthesis" EXACT [] +synonym: "THF polyglutamylation" EXACT [GOC:bf, KEGG:ec00790] +is_a: GO:0009396 ! folic acid-containing compound biosynthetic process +is_a: GO:0046900 ! tetrahydrofolylpolyglutamate metabolic process + +[Term] +id: GO:0046902 +name: regulation of mitochondrial membrane permeability +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane." [GOC:bf] +synonym: "regulation of mitochondrial envelope permeability" RELATED [] +synonym: "regulation of transport across mitochondrial membrane" EXACT [] +is_a: GO:0007006 ! mitochondrial membrane organization +is_a: GO:0090559 ! regulation of membrane permeability +relationship: part_of GO:0006839 ! mitochondrial transport + +[Term] +id: GO:0046903 +name: secretion +namespace: biological_process +def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] +subset: goslim_pir +is_a: GO:0006810 ! transport + +[Term] +id: GO:0046904 +name: calcium oxalate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi." [ISBN:0721662544] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0046905 +name: phytoene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate." [GOC:ai, PMID:12641468] +comment: Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32. +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +relationship: part_of GO:0016120 ! carotene biosynthetic process + +[Term] +id: GO:0046906 +name: tetrapyrrole binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position." [GOC:curators, ISBN:0198506732] +subset: goslim_metagenomics +subset: goslim_pir +synonym: "porphyrin binding" NARROW [] +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0046907 +name: intracellular transport +namespace: biological_process +alt_id: GO:1902582 +def: "The directed movement of substances within a cell." [GOC:ai] +synonym: "single organism intracellular transport" RELATED [GOC:TermGenie] +synonym: "single-organism intracellular transport" RELATED [] +is_a: GO:0006810 ! transport +is_a: GO:0051641 ! cellular localization +is_a: GO:0051649 ! establishment of localization in cell +intersection_of: GO:0006810 ! transport +intersection_of: occurs_in GO:0005622 ! intracellular +relationship: occurs_in GO:0005622 ! intracellular +created_by: jl +creation_date: 2013-12-18T14:04:50Z + +[Term] +id: GO:0046908 +name: obsolete negative regulation of crystal formation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the spontaneous (nonenzymatic) formation of crystals in a solution, for example, calcium oxalate crystals in urine." [GOC:ai] +comment: This term was made obsolete because a more appropriate term was created. +synonym: "negative regulation of crystal formation" EXACT [] +synonym: "negative regulation of mineralization" RELATED [] +is_obsolete: true +replaced_by: GO:0050801 + +[Term] +id: GO:0046909 +name: obsolete intermembrane transport +namespace: biological_process +def: "OBSOLETE. The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions." [GOC:ai, GOC:pr, PMID:10671554] +comment: The reason for obsoletion is that this term was incorrectly named, defined, and placed in the ontology, and thus had been used to annotate two unrelated processes of [intermembrane lipid transfer] and processes related to [vesicular transport]. It was also inappropriately used as the parent term for [protein transport from ciliary membrane to plasma membrane], which has already been moved to an appropriate location as a child of [protein transport within lipid bilayer]. +is_obsolete: true +consider: GO:0016192 +consider: GO:0120009 + +[Term] +id: GO:0046910 +name: pectinesterase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of any pectinesterase enzyme." [GOC:ai, PMID:10880981] +comment: See also the molecular function term 'pectinesterase activity ; GO:0030599'. +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0030599 ! pectinesterase activity + +[Term] +id: GO:0046911 +name: metal chelating activity +namespace: molecular_function +def: "The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring." [ISBN:0198506732, ISBN:0716731363] +synonym: "heavy metal chelation" NARROW [] +synonym: "metal chelation" EXACT [] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0046912 +name: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer +namespace: molecular_function +def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer." [GOC:jl] +xref: EC:2.3.3 +is_a: GO:0016746 ! transferase activity, transferring acyl groups + +[Term] +id: GO:0046914 +name: transition metal ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] +is_a: GO:0046872 ! metal ion binding + +[Term] +id: GO:0046915 +name: transition metal ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732] +is_a: GO:0046873 ! metal ion transmembrane transporter activity +relationship: part_of GO:0000041 ! transition metal ion transport + +[Term] +id: GO:0046916 +name: cellular transition metal ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [GOC:mah, ISBN:0198506732] +is_a: GO:0006875 ! cellular metal ion homeostasis +is_a: GO:0055076 ! transition metal ion homeostasis + +[Term] +id: GO:0046917 +name: triphosphoribosyl-dephospho-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine." [EC:2.4.2.52] +synonym: "2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity" EXACT [EC:2.4.2.52] +synonym: "ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity" EXACT [] +synonym: "ATP:dephospho-CoA 5-triphosphoribosyl transferase activity" EXACT [] +synonym: "CitG activity" RELATED [] +xref: EC:2.4.2.52 +xref: MetaCyc:2.7.8.25-RXN +xref: RHEA:15117 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0046918 +name: N-terminal peptidyl-glycine N-palmitoylation +namespace: biological_process +def: "The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine." [RESID:AA0339] +comment: Palmitoylation of glycine only occurs when glycine is at the N-terminal position of a protein. +xref: RESID:AA0339 +is_a: GO:0006500 ! N-terminal protein palmitoylation + +[Term] +id: GO:0046919 +name: pyruvyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0046920 +name: alpha-(1->3)-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage." [GOC:ai] +synonym: "alpha(1,3)-fucosyltransferase activity" EXACT [] +synonym: "alpha-(1,3)-fucosyltransferase activity" EXACT [] +synonym: "alpha-1,3-fucosyltransferase activity" EXACT [] +xref: Reactome:R-HSA-9603984 "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX" +xref: Reactome:R-HSA-9605609 "FUT3 transfers Fuc to Type 1 MSGG to form sLeA" +xref: Reactome:R-HSA-9605644 "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA" +xref: Reactome:R-HSA-9605682 "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX" +is_a: GO:0008417 ! fucosyltransferase activity + +[Term] +id: GO:0046921 +name: alpha-(1->6)-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage." [GOC:ai] +synonym: "alpha(1,6)-fucosyltransferase activity" EXACT [] +synonym: "alpha-(1,6)-fucosyltransferase activity" EXACT [] +synonym: "alpha-1,6-fucosyltransferase activity" EXACT [] +is_a: GO:0008417 ! fucosyltransferase activity + +[Term] +id: GO:0046922 +name: peptide-O-fucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor." [EC:2.4.1.221] +synonym: "GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.221] +synonym: "GDP-fucose protein O-fucosyltransferase activity" EXACT [EC:2.4.1.221] +synonym: "GDP-fucose:polypeptide fucosyltransferase activity" EXACT [EC:2.4.1.221] +synonym: "GDP-L-fucose:polypeptide fucosyltransferase activity" EXACT [EC:2.4.1.221] +xref: EC:2.4.1.221 +xref: MetaCyc:2.4.1.221-RXN +xref: Reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1" +xref: Reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins" +is_a: GO:0008417 ! fucosyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0036066 ! protein O-linked fucosylation + +[Term] +id: GO:0046923 +name: ER retention sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER." [GOC:ai] +synonym: "endoplasmic reticulum retention sequence binding" EXACT [] +is_a: GO:0005048 ! signal sequence binding + +[Term] +id: GO:0046924 +name: peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine +namespace: biological_process +def: "The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine." [PMID:12696888, RESID:AA0340] +xref: RESID:AA0340 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0046925 +name: peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine +namespace: biological_process +def: "The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine." [PMID:12696888, RESID:AA0341] +xref: RESID:AA0341 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018207 ! peptidyl-phenylalanine modification + +[Term] +id: GO:0046926 +name: peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine +namespace: biological_process +def: "The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine." [PMID:12696888, RESID:AA0342] +xref: RESID:AA0342 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0046927 +name: peptidyl-threonine racemization +namespace: biological_process +def: "The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine." [PMID:12696888] +is_a: GO:0018085 ! peptidyl-L-amino acid racemization +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0046928 +name: regulation of neurotransmitter secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007269 ! neurotransmitter secretion +relationship: regulates GO:0007269 ! neurotransmitter secretion + +[Term] +id: GO:0046929 +name: negative regulation of neurotransmitter secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] +synonym: "conotoxin activity" NARROW [] +synonym: "down regulation of neurotransmitter secretion" EXACT [] +synonym: "down-regulation of neurotransmitter secretion" EXACT [] +synonym: "downregulation of neurotransmitter secretion" EXACT [] +synonym: "inhibition of neurotransmitter secretion" NARROW [] +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0050805 ! negative regulation of synaptic transmission +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007269 ! neurotransmitter secretion +relationship: negatively_regulates GO:0007269 ! neurotransmitter secretion + +[Term] +id: GO:0046930 +name: pore complex +namespace: cellular_component +def: "Any small opening in a membrane that allows the passage of gases and/or liquids." [ISBN:0198506732] +synonym: "channel-forming toxin activity" RELATED [] +synonym: "pore" EXACT [] +synonym: "pore-forming toxin activity" RELATED [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0016021 ! integral component of membrane + +[Term] +id: GO:0046931 +name: pore complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases." [GOC:jl, GOC:mah] +comment: See also the cellular component term 'pore complex ; GO:0046930'. +synonym: "pore biosynthesis" EXACT [] +synonym: "pore complex biogenesis" RELATED [GOC:mah] +synonym: "pore formation" EXACT [] +synonym: "pore-forming toxin activity" RELATED [] +is_a: GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0046932 +name: sodium-transporting ATP synthase activity, rotational mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism." [EC:7.2.2.1, RHEA:58158, TC:3.A.2.1.2] +synonym: "sodium-translocating F-type ATPase activity" EXACT [] +synonym: "sodium-transporting two-sector ATPase activity" EXACT [] +xref: EC:7.2.2.1 +xref: MetaCyc:3.6.3.15-RXN +xref: RHEA:58158 +is_a: GO:0015081 ! sodium ion transmembrane transporter activity + +[Term] +id: GO:0046933 +name: proton-transporting ATP synthase activity, rotational mechanism +namespace: molecular_function +def: "Enables the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism." [EC:7.1.2.2, TC:3.A.2.1.1] +synonym: "H+-transporting ATP synthase activity" EXACT [EC:7.1.2.2] +synonym: "hydrogen ion translocating F-type ATPase activity" EXACT [] +synonym: "hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [] +synonym: "hydrogen ion transporting two-sector ATPase activity" EXACT [] +xref: MetaCyc:ATPSYN-RXN +xref: Reactome:R-HSA-164832 "ATPase synthesizes ATP" +xref: RHEA:57722 +is_a: GO:0015252 ! proton channel activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0046934 +name: phosphatidylinositol-4,5-bisphosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)." [EC:2.7.1.153, RHEA:21292] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.153] +synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] +synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] +synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] +synonym: "type I phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.153] +xref: EC:2.7.1.153 +xref: KEGG_REACTION:R04545 +xref: MetaCyc:2.7.1.153-RXN +xref: Reactome:R-HSA-1226014 "Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants" +xref: Reactome:R-HSA-1250370 "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers" +xref: Reactome:R-HSA-1250462 "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3" +xref: Reactome:R-HSA-1306957 "PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR" +xref: Reactome:R-HSA-1306979 "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1" +xref: Reactome:R-HSA-1676048 "PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane" +xref: Reactome:R-HSA-177939 "PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3)" +xref: Reactome:R-HSA-1839091 "Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-1839107 "BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3." +xref: Reactome:R-HSA-186800 "PI3K catalyses the phosphorylation of PIP2 to PIP3" +xref: Reactome:R-HSA-198266 "PI3K produces PIP3 and other phosphatidyl inositides" +xref: Reactome:R-HSA-202365 "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-2029271 "PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-2076220 "CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3" +xref: Reactome:R-HSA-2316434 "PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-2394007 "PI3K gain of function mutants phosphorylate PIP2 to PIP3" +xref: Reactome:R-HSA-2424480 "PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-2730870 "Phosphorylation of PIP2 to PIP3 by PI3K" +xref: Reactome:R-HSA-389158 "CD28 bound PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-392300 "G beta:gamma activated PI3Kgamma converts PIP2 to PIP3" +xref: Reactome:R-HSA-437162 "PI3K alpha, beta, gamma convert PIP2 to PIP3" +xref: Reactome:R-HSA-5218819 "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5637801 "Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII" +xref: Reactome:R-HSA-5654690 "FGFR1-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654692 "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654697 "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654701 "FGFR2-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654705 "FGFR3-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654709 "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654714 "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5654717 "FGFR4-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5655235 "Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5655289 "Activated FGFR3 mutant-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5655290 "Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-5655323 "Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-8852019 "MET bound PI3K generates PIP3" +xref: Reactome:R-HSA-8853323 "Activated FGFR3 fusion-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-9021627 "EPOR-associated PI3K phosphorylates PIP2 to PIP3" +xref: Reactome:R-HSA-9603445 "Activated NTRK3 stimulates PI3K activity" +xref: RHEA:21292 +is_a: GO:0035004 ! phosphatidylinositol 3-kinase activity +is_a: GO:0052813 ! phosphatidylinositol bisphosphate kinase activity + +[Term] +id: GO:0046935 +name: 1-phosphatidylinositol-3-kinase regulator activity +namespace: molecular_function +def: "Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity." [GOC:ai] +comment: See also the molecular function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'. +synonym: "1-phosphatidylinositol 3-kinase regulator activity" EXACT [] +synonym: "phosphatidylinositol 3-kinase, class I, regulator activity" NARROW [] +is_a: GO:0035014 ! phosphatidylinositol 3-kinase regulator activity +relationship: regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity + +[Term] +id: GO:0046936 +name: deoxyadenosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxyadenosine + H2O = deoxyinosine + NH3." [EC:3.5.4.4, GOC:ai] +synonym: "deoxyadenosine deaminase reaction" EXACT [] +xref: MetaCyc:ADDALT-RXN +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0046937 +name: phytochelatin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." [ISBN:0198506732] +synonym: "cadystin metabolic process" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "cadystin metabolism" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "phytochelatin metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0019748 ! secondary metabolic process + +[Term] +id: GO:0046938 +name: phytochelatin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11." [ISBN:0198506732] +synonym: "cadystin biosynthetic process" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "phytochelatin anabolism" EXACT [] +synonym: "phytochelatin biosynthesis" EXACT [] +synonym: "phytochelatin formation" EXACT [] +synonym: "phytochelatin synthesis" EXACT [] +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046937 ! phytochelatin metabolic process + +[Term] +id: GO:0046939 +name: nucleotide phosphorylation +namespace: biological_process +def: "The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside." [GOC:ai] +is_a: GO:0016310 ! phosphorylation + +[Term] +id: GO:0046940 +name: nucleoside monophosphate phosphorylation +namespace: biological_process +def: "The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside." [GOC:ai] +is_a: GO:0009123 ! nucleoside monophosphate metabolic process +is_a: GO:0009165 ! nucleotide biosynthetic process + +[Term] +id: GO:0046941 +name: azetidine-2-carboxylic acid acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid." [PMID:12761200] +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0046942 +name: carboxylic acid transport +namespace: biological_process +def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015849 ! organic acid transport + +[Term] +id: GO:0046943 +name: carboxylic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] +xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" +is_a: GO:0005342 ! organic acid transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0046944 +name: protein carbamoylation +namespace: biological_process +def: "The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2." [GOC:ai] +synonym: "protein amino acid carbamoylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0046945 +name: N-terminal peptidyl-alanine N-carbamoylation +namespace: biological_process +def: "The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine." [RESID:AA0343] +synonym: "N-terminal peptidyl-alanine N-carbamylation" RELATED [] +xref: RESID:AA0343 +is_a: GO:0018194 ! peptidyl-alanine modification +is_a: GO:0046944 ! protein carbamoylation +is_a: GO:0050990 ! N-terminal protein amino acid carbamoylation + +[Term] +id: GO:0046946 +name: hydroxylysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases." [ISBN:0198506732, PubChem_Compound:1029] +synonym: "hydroxylysine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0009066 ! aspartate family amino acid metabolic process + +[Term] +id: GO:0046947 +name: hydroxylysine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid." [ISBN:0198506732] +synonym: "hydroxylysine anabolism" EXACT [] +synonym: "hydroxylysine biosynthesis" EXACT [] +synonym: "hydroxylysine formation" EXACT [] +synonym: "hydroxylysine synthesis" EXACT [] +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0046946 ! hydroxylysine metabolic process + +[Term] +id: GO:0046948 +name: hydroxylysine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid." [ISBN:0198506732] +synonym: "hydroxylysine breakdown" EXACT [] +synonym: "hydroxylysine catabolism" EXACT [] +synonym: "hydroxylysine degradation" EXACT [] +is_a: GO:0009068 ! aspartate family amino acid catabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046946 ! hydroxylysine metabolic process + +[Term] +id: GO:0046949 +name: fatty-acyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group." [ISBN:0198506732] +synonym: "fatty acyl CoA biosynthetic process" EXACT [] +synonym: "fatty-acyl-CoA anabolism" EXACT [] +synonym: "fatty-acyl-CoA biosynthesis" EXACT [] +synonym: "fatty-acyl-CoA formation" EXACT [] +synonym: "fatty-acyl-CoA synthesis" EXACT [] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +is_a: GO:0071616 ! acyl-CoA biosynthetic process +is_a: GO:1901570 ! fatty acid derivative biosynthetic process + +[Term] +id: GO:0046950 +name: cellular ketone body metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism." [ISBN:0198506732] +subset: goslim_pir +synonym: "cellular ketone body metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0046951 +name: ketone body biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA." [ISBN:0198506732] +synonym: "ketone body anabolism" EXACT [] +synonym: "ketone body biosynthesis" EXACT [] +synonym: "ketone body formation" EXACT [] +synonym: "ketone body synthesis" EXACT [] +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0044283 ! small molecule biosynthetic process +is_a: GO:0046950 ! cellular ketone body metabolic process +is_a: GO:1901570 ! fatty acid derivative biosynthetic process +is_a: GO:1902224 ! ketone body metabolic process + +[Term] +id: GO:0046952 +name: ketone body catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA." [ISBN:0198506732] +synonym: "ketolysis" EXACT [MetaCyc:PWY66-368] +synonym: "ketone body breakdown" EXACT [] +synonym: "ketone body catabolism" EXACT [Reactome:R-HSA-77108] +synonym: "ketone body degradation" EXACT [] +synonym: "utilization of ketone bodies" EXACT [Reactome:R-HSA-77108] +xref: MetaCyc:PWY66-368 +xref: Reactome:R-HSA-77108 +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044282 ! small molecule catabolic process +is_a: GO:0046950 ! cellular ketone body metabolic process +is_a: GO:1901569 ! fatty acid derivative catabolic process +is_a: GO:1902224 ! ketone body metabolic process + +[Term] +id: GO:0046956 +name: positive phototaxis +namespace: biological_process +alt_id: GO:0046954 +def: "The directed movement of a cell or organism towards a source of light." [GOC:ai] +synonym: "positive phototactic behavior" EXACT [] +synonym: "positive phototactic behaviour" EXACT [] +synonym: "positive taxis in response to light" EXACT [] +is_a: GO:0042331 ! phototaxis +is_a: GO:0052128 ! positive energy taxis + +[Term] +id: GO:0046957 +name: negative phototaxis +namespace: biological_process +alt_id: GO:0046955 +def: "The directed movement of a cell or organism away from a source of light." [GOC:ai] +synonym: "negative phototactic behavior" EXACT [] +synonym: "negative phototactic behaviour" EXACT [] +synonym: "negative taxis in response to light" EXACT [] +is_a: GO:0042331 ! phototaxis +is_a: GO:0052129 ! negative energy taxis + +[Term] +id: GO:0046958 +name: nonassociative learning +namespace: biological_process +def: "A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment." [ISBN:0582227089] +synonym: "unconditional response" EXACT [] +is_a: GO:0007612 ! learning + +[Term] +id: GO:0046959 +name: habituation +namespace: biological_process +def: "A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented." [ISBN:0582227089] +xref: Wikipedia:Habituation +is_a: GO:0046958 ! nonassociative learning + +[Term] +id: GO:0046960 +name: sensitization +namespace: biological_process +def: "An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched." [ISBN:0582227089] +xref: Wikipedia:Sensitization +is_a: GO:0046958 ! nonassociative learning + +[Term] +id: GO:0046961 +name: proton-transporting ATPase activity, rotational mechanism +namespace: molecular_function +def: "Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism." [EC:3.6.3.14] +synonym: "ATP phosphohydrolase (H+-transporting) activity" EXACT [EC:3.6.3.14] +synonym: "ATP synthase activity" BROAD [EC:3.6.3.14] +synonym: "bacterial Ca2+/Mg2+ ATPase" NARROW [EC:3.6.3.14] +synonym: "chloroplast ATPase activity" NARROW [EC:3.6.3.14] +synonym: "coupling factors (Fo, F1 and CF1)" RELATED [EC:3.6.3.14] +synonym: "F(0)F(1)-ATPase activity" NARROW [EC:3.6.3.14] +synonym: "F(1)-ATPase activity" NARROW [EC:3.6.3.14] +synonym: "F(o)F(1)-ATPase activity" NARROW [EC:3.6.3.14] +synonym: "F0F1-ATPase" NARROW [EC:3.6.3.14] +synonym: "F1-ATPase" NARROW [EC:3.6.3.14] +synonym: "FoF1-ATPase" NARROW [EC:3.6.3.14] +synonym: "H(+)-transporting ATP synthase activity" EXACT [EC:3.6.3.14] +synonym: "H(+)-transporting ATPase activity" BROAD [EC:3.6.3.14] +synonym: "H+-transporting ATPase activity" EXACT [EC:3.6.3.14] +synonym: "H+-transporting two-sector ATPase" NARROW [EC:3.6.3.14] +synonym: "hydrogen ion translocating A-type ATPase activity" NARROW [] +synonym: "hydrogen ion translocating F-type ATPase activity" NARROW [] +synonym: "hydrogen ion translocating V-type ATPase activity" NARROW [] +synonym: "hydrogen ion transporting ATPase activity, rotational mechanism" EXACT [] +synonym: "hydrogen ion transporting two-sector ATPase activity" NARROW [] +synonym: "mitochondrial ATPase activity" NARROW [EC:3.6.3.14] +xref: MetaCyc:ATPSYN-RXN +xref: RHEA:57721 +is_a: GO:0009678 ! pyrophosphate hydrolysis-driven proton transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity +is_a: GO:0044769 ! ATPase activity, coupled to transmembrane movement of ions, rotational mechanism + +[Term] +id: GO:0046962 +name: sodium-transporting ATPase activity, rotational mechanism +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) => ADP + phosphate + Na+(out), by a rotational mechanism." [EC:7.2.2.1, RHEA:58157] +synonym: "ATP phosphohydrolase (Na+-transporting) activity" RELATED [] +synonym: "ATP synthase, sodium ion specific activity" EXACT [EC:7.2.2.1] +synonym: "Na(+)-translocating ATPase activity" BROAD [] +synonym: "Na(+)-transporting two-sector ATPase activity" EXACT [EC:7.2.2.1] +synonym: "Na+-translocating ATPase activity" EXACT [EC:7.2.2.1] +synonym: "Na+-translocating F1Fo-ATPase" NARROW [] +synonym: "Na+-transporting two-sector ATPase" NARROW [EC:7.2.2.1] +synonym: "sodium transporting ATPase activity, rotational mechanism" EXACT [] +synonym: "sodium-translocating F-type ATPase activity" NARROW [] +synonym: "sodium-translocating V-type ATPase activity" NARROW [] +synonym: "sodium-transporting two-sector ATPase activity" NARROW [] +synonym: "vacuolar-type Na+-ATPase" NARROW [] +synonym: "vacuolar-type Na+-translocating ATPase" NARROW [] +xref: EC:7.2.2.1 +xref: MetaCyc:3.6.3.15-RXN +xref: RHEA:58157 +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0019829 ! ATPase-coupled cation transmembrane transporter activity +is_a: GO:0044769 ! ATPase activity, coupled to transmembrane movement of ions, rotational mechanism + +[Term] +id: GO:0046963 +name: 3'-phosphoadenosine 5'-phosphosulfate transport +namespace: biological_process +def: "The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] +synonym: "3'-phosphoadenosine 5'-phosphosulphate transport" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate transport" EXACT [] +synonym: "PAPS transport" EXACT [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:0072348 ! sulfur compound transport + +[Term] +id: GO:0046964 +name: 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other." [ISBN:0198506732] +synonym: "3'-phosphoadenosine 5'-phosphosulphate transporter activity" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity" EXACT [] +synonym: "PAPS transporter activity" EXACT [] +xref: Reactome:R-HSA-741449 "SLC35B2,3 transport cytosolic PAPS to Golgi lumen" +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:1902559 ! 3'-phospho-5'-adenylyl sulfate transmembrane transport + +[Term] +id: GO:0046965 +name: retinoid X receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a retinoid X receptor." [GOC:ai] +synonym: "RXR binding" EXACT [] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0042974 ! retinoic acid receptor binding + +[Term] +id: GO:0046966 +name: thyroid hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a thyroid hormone receptor." [GOC:ai] +synonym: "ligand-dependent thyroid hormone receptor interactor activity" NARROW [] +is_a: GO:0035257 ! nuclear hormone receptor binding + +[Term] +id: GO:0046967 +name: cytosol to endoplasmic reticulum transport +namespace: biological_process +def: "The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell." [GOC:ai] +synonym: "cytosol to endoplasmic reticulum transport" EXACT [] +synonym: "cytosol to ER transport" EXACT [] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0046968 +name: peptide antigen transport +namespace: biological_process +def: "The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein." [GOC:add, ISBN:0781735149, PMID:15771591] +is_a: GO:0015833 ! peptide transport +relationship: part_of GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0046969 +name: NAD-dependent histone deacetylase activity (H3-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein." [EC:3.5.1.17, RHEA:24548] +xref: Reactome:R-HSA-9604829 "SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters" +is_a: GO:0017136 ! NAD-dependent histone deacetylase activity +is_a: GO:0032129 ! histone deacetylase activity (H3-K9 specific) + +[Term] +id: GO:0046970 +name: NAD-dependent histone deacetylase activity (H4-K16 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein." [EC:3.5.1.17, GOC:vw, RHEA:24548] +is_a: GO:0017136 ! NAD-dependent histone deacetylase activity +is_a: GO:0034739 ! histone deacetylase activity (H4-K16 specific) + +[Term] +id: GO:0046972 +name: histone acetyltransferase activity (H4-K16 specific) +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4." [EC:2.3.1.48] +synonym: "histone lysine acetyltransferase activity (H4-K16 specific)" EXACT [] +is_a: GO:0010485 ! H4 histone acetyltransferase activity +relationship: part_of GO:0043984 ! histone H4-K16 acetylation + +[Term] +id: GO:0046973 +name: obsolete histone lysine N-methyltransferase activity (H3-K24 specific) +namespace: molecular_function +def: "OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein." [GOC:ai] +comment: This term was made obsolete because there is no lysine at position 24 of histone H3. +synonym: "histone lysine N-methyltransferase activity (H3-K24 specific)" EXACT [] +is_obsolete: true +consider: GO:0042800 + +[Term] +id: GO:0046974 +name: histone methyltransferase activity (H3-K9 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein." [GOC:ai] +synonym: "histone lysine N-methyltransferase activity (H3-K9 specific)" EXACT [] +synonym: "histone methylase activity (H3-K9 specific)" EXACT [GOC:mah] +xref: Reactome:R-HSA-427336 "TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9." +xref: Reactome:R-HSA-427527 "eNoSC dimethylates histone H3 at lysine-9" +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0051567 ! histone H3-K9 methylation + +[Term] +id: GO:0046975 +name: histone methyltransferase activity (H3-K36 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein." [GOC:ai] +synonym: "histone lysine N-methyltransferase activity (H3-K36 specific)" EXACT [] +synonym: "histone methylase activity (H3-K36 specific)" EXACT [GOC:mah] +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0010452 ! histone H3-K36 methylation + +[Term] +id: GO:0046976 +name: histone methyltransferase activity (H3-K27 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein." [GOC:ai] +synonym: "histone lysine N-methyltransferase activity (H3-K27 specific)" EXACT [] +synonym: "histone methylase activity (H3-K27 specific)" EXACT [GOC:mah] +xref: Reactome:R-HSA-3240295 "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter" +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +relationship: part_of GO:0070734 ! histone H3-K27 methylation + +[Term] +id: GO:0046977 +name: TAP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2." [PMID:11133832] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0046978 +name: TAP1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the TAP1 subunit of TAP (transporter associated with antigen processing) protein." [PMID:11133832] +is_a: GO:0046977 ! TAP binding + +[Term] +id: GO:0046979 +name: TAP2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the TAP2 subunit of TAP (transporter associated with antigen processing) protein." [PMID:11133832] +is_a: GO:0046977 ! TAP binding + +[Term] +id: GO:0046980 +name: tapasin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules." [PMID:12594855] +synonym: "TAP binding protein binding" EXACT [HGNC:11566] +synonym: "TAPBP binding" RELATED [HGNC:11566] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0046981 +name: beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids." [GOC:bf, PMID:12130631, PMID:12130651] +synonym: "UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [] +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0046982 +name: protein heterodimerization activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer." [GOC:ai] +subset: goslim_chembl +is_a: GO:0046983 ! protein dimerization activity + +[Term] +id: GO:0046983 +name: protein dimerization activity +namespace: molecular_function +def: "The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits." [ISBN:0198506732] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0046984 +name: regulation of hemoglobin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] +synonym: "regulation of haemoglobin biosynthesis" EXACT [] +synonym: "regulation of haemoglobin biosynthetic process" EXACT [] +synonym: "regulation of hemoglobin anabolism" EXACT [] +synonym: "regulation of hemoglobin biosynthesis" EXACT [] +synonym: "regulation of hemoglobin formation" EXACT [] +synonym: "regulation of hemoglobin synthesis" EXACT [] +is_a: GO:0051246 ! regulation of protein metabolic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042541 ! hemoglobin biosynthetic process +relationship: regulates GO:0042541 ! hemoglobin biosynthetic process + +[Term] +id: GO:0046985 +name: positive regulation of hemoglobin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] +synonym: "activation of hemoglobin biosynthetic process" NARROW [] +synonym: "positive regulation of haemoglobin biosynthesis" EXACT [] +synonym: "positive regulation of haemoglobin biosynthetic process" EXACT [] +synonym: "positive regulation of hemoglobin anabolism" EXACT [] +synonym: "positive regulation of hemoglobin biosynthesis" EXACT [] +synonym: "positive regulation of hemoglobin formation" EXACT [] +synonym: "positive regulation of hemoglobin synthesis" EXACT [] +synonym: "stimulation of hemoglobin biosynthetic process" NARROW [] +synonym: "up regulation of hemoglobin biosynthetic process" EXACT [] +synonym: "up-regulation of hemoglobin biosynthetic process" EXACT [] +synonym: "upregulation of hemoglobin biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046984 ! regulation of hemoglobin biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042541 ! hemoglobin biosynthetic process +relationship: positively_regulates GO:0042541 ! hemoglobin biosynthetic process + +[Term] +id: GO:0046986 +name: negative regulation of hemoglobin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] +synonym: "down regulation of hemoglobin biosynthetic process" EXACT [] +synonym: "down-regulation of hemoglobin biosynthetic process" EXACT [] +synonym: "downregulation of hemoglobin biosynthetic process" EXACT [] +synonym: "inhibition of hemoglobin biosynthetic process" NARROW [] +synonym: "negative regulation of haemoglobin biosynthesis" EXACT [] +synonym: "negative regulation of haemoglobin biosynthetic process" EXACT [] +synonym: "negative regulation of hemoglobin anabolism" EXACT [] +synonym: "negative regulation of hemoglobin biosynthesis" EXACT [] +synonym: "negative regulation of hemoglobin formation" EXACT [] +synonym: "negative regulation of hemoglobin synthesis" EXACT [] +is_a: GO:0046984 ! regulation of hemoglobin biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042541 ! hemoglobin biosynthetic process +relationship: negatively_regulates GO:0042541 ! hemoglobin biosynthetic process + +[Term] +id: GO:0046987 +name: N-acetyllactosamine beta-1,3-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine)." [GOC:bf, PMID:12511570] +synonym: "galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity" EXACT [] +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0046988 +name: asioloorosomucoid beta-1,3-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid." [GOC:bf, PMID:12511570] +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0046989 +name: galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids." [GOC:bf, PMID:12511570] +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0046990 +name: N-hydroxyarylamine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine." [EC:2.3.1.118, MetaCyc:2.3.1.118-RXN] +synonym: "acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity" EXACT [EC:2.3.1.118] +synonym: "arylhydroxamate N,O-acetyltransferase activity" EXACT [EC:2.3.1.118] +synonym: "N-hydroxy-2-aminofluorene-O-acetyltransferase activity" EXACT [EC:2.3.1.118] +xref: EC:2.3.1.118 +xref: MetaCyc:2.3.1.118-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0046992 +name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y." [GOC:ai] +synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors" NARROW [] +xref: EC:1.21 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0046993 +name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen." [GOC:ai] +xref: EC:1.21.3 +is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond + +[Term] +id: GO:0046994 +name: oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound." [GOC:jl] +xref: EC:1.12.5 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0046995 +name: oxidoreductase activity, acting on hydrogen as donor, with other known acceptors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound." [GOC:ai] +xref: EC:1.12.98 +is_a: GO:0016695 ! oxidoreductase activity, acting on hydrogen as donor + +[Term] +id: GO:0046996 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated." [GOC:mah] +synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated" RELATED [] +xref: EC:1.14.21 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0046997 +name: oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin." [GOC:jl] +xref: EC:1.5.8 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0046998 +name: (S)-usnate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH." [EC:1.1.1.199, RHEA:21876] +synonym: "L-usnic acid dehydrogenase activity" EXACT [EC:1.1.1.199] +synonym: "reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming)" EXACT [EC:1.1.1.199] +xref: EC:1.1.1.199 +xref: KEGG_REACTION:R07345 +xref: MetaCyc:1.1.1.199-RXN +xref: RHEA:21876 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0046999 +name: regulation of conjugation +namespace: biological_process +def: "Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual." [GOC:ai] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000746 ! conjugation +relationship: regulates GO:0000746 ! conjugation + +[Term] +id: GO:0047000 +name: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH." [EC:1.1.1.126, RHEA:15109] +synonym: "2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.126] +synonym: "2-keto-3-deoxy-D-gluconate dehydrogenase activity" EXACT [EC:1.1.1.126] +xref: EC:1.1.1.126 +xref: KEGG_REACTION:R01543 +xref: MetaCyc:1.1.1.126-RXN +xref: RHEA:15109 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047001 +name: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate." [EC:1.1.1.127, MetaCyc:1.1.1.127-RXN] +synonym: "2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.127] +synonym: "2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity" EXACT [EC:1.1.1.127] +synonym: "2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity" EXACT [EC:1.1.1.127] +synonym: "2-keto-3-deoxygluconate 5-dehydrogenase activity" EXACT [EC:1.1.1.127] +synonym: "2-keto-3-deoxygluconate dehydrogenase activity" EXACT [EC:1.1.1.127] +xref: EC:1.1.1.127 +xref: MetaCyc:1.1.1.127-RXN +xref: RHEA:24232 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047002 +name: L-arabinitol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH." [EC:1.1.1.13, RHEA:21356] +synonym: "L-arabinitol 2-dehydrogenase (ribulose forming) activity" EXACT [] +xref: EC:1.1.1.13 +xref: KEGG_REACTION:R02441 +xref: MetaCyc:1.1.1.13-RXN +xref: RHEA:21356 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047003 +name: dTDP-6-deoxy-L-talose 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH." [EC:1.1.1.134, RHEA:23648] +synonym: "dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)" EXACT [EC:1.1.1.134] +synonym: "dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.134] +synonym: "TDP-6-deoxy-L-talose dehydrogenase activity" EXACT [EC:1.1.1.134] +synonym: "thymidine diphospho-6-deoxy-L-talose dehydrogenase activity" EXACT [EC:1.1.1.134] +xref: EC:1.1.1.134 +xref: KEGG_REACTION:R02776 +xref: MetaCyc:1.1.1.134-RXN +xref: RHEA:23648 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047004 +name: UDP-N-acetylglucosamine 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate." [EC:1.1.1.136, RHEA:13325] +synonym: "UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity" EXACT [EC:1.1.1.136] +synonym: "UDP-GLcNAc dehydrogenase activity" EXACT [EC:1.1.1.136] +synonym: "UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.136] +synonym: "UDPacetylglucosamine dehydrogenase activity" EXACT [EC:1.1.1.136] +synonym: "uridine diphosphoacetylglucosamine dehydrogenase activity" EXACT [EC:1.1.1.136] +xref: EC:1.1.1.136 +xref: KEGG_REACTION:R00421 +xref: MetaCyc:1.1.1.136-RXN +xref: RHEA:13325 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047005 +name: 16-alpha-hydroxysteroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid." [EC:1.1.1.147, MetaCyc:1.1.1.147-RXN] +synonym: "16alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.147] +synonym: "16alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.147] +synonym: "16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity" EXACT [EC:1.1.1.147] +xref: EC:1.1.1.147 +xref: MetaCyc:1.1.1.147-RXN +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047006 +name: 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone." [EC:1.1.1.149, MetaCyc:1.1.1.149-RXN] +synonym: "20alpha-HSD" RELATED [EC:1.1.1.149] +synonym: "20alpha-HSDH" RELATED [EC:1.1.1.149] +synonym: "20alpha-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.149] +synonym: "20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.149] +synonym: "20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity" BROAD [EC:1.1.1.149] +xref: EC:1.1.1.149 +xref: MetaCyc:1.1.1.149-RXN +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047007 +name: pregnan-21-ol dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al." [EC:1.1.1.150, RHEA:11448] +synonym: "21-hydroxysteroid dehydrogenase (NAD+) activity" BROAD [EC:1.1.1.50] +synonym: "21-hydroxysteroid:NAD+ 21-oxidoreductase activity" BROAD [EC:1.1.1.150] +xref: EC:1.1.1.150 +xref: KEGG_REACTION:R03043 +xref: MetaCyc:1.1.1.150-RXN +xref: RHEA:11448 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047008 +name: pregnan-21-ol dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al." [EC:1.1.1.151, RHEA:23712] +synonym: "21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" BROAD [EC:1.1.1.151] +synonym: "21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity" BROAD [EC:1.1.1.151] +synonym: "21-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.151] +synonym: "21-hydroxysteroid dehydrogenase (NADP+) activity" BROAD [EC:1.1.1.151] +synonym: "21-hydroxysteroid:NADP+ 21-oxidoreductase activity" BROAD [EC:1.1.1.151] +synonym: "NADP-21-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.151] +xref: EC:1.1.1.151 +xref: KEGG_REACTION:R03044 +xref: MetaCyc:1.1.1.151-RXN +xref: RHEA:23712 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047009 +name: 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione." [EC:1.1.1.152, MetaCyc:1.1.1.152-RXN] +synonym: "3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] +synonym: "3alpha-hydroxy-5beta-steroid dehydrogenase activity" EXACT [EC:1.1.1.152] +synonym: "3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.152] +synonym: "etiocholanolone 3-alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] +synonym: "etiocholanolone 3alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] +xref: EC:1.1.1.152 +xref: MetaCyc:1.1.1.152-RXN +xref: RHEA:10356 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047010 +name: hydroxycyclohexanecarboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH." [EC:1.1.1.166, RHEA:10516] +synonym: "(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity" EXACT [EC:1.1.1.166] +synonym: "(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.166] +synonym: "dihydroxycyclohexanecarboxylate dehydrogenase activity" EXACT [EC:1.1.1.166] +xref: EC:1.1.1.166 +xref: KEGG_REACTION:R05315 +xref: MetaCyc:1.1.1.166-RXN +xref: RHEA:10516 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047011 +name: 2-dehydropantolactone reductase (A-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+." [EC:1.1.1.168, MetaCyc:1.1.1.168-RXN] +synonym: "(R)-pantolactone:NADP+ oxidoreductase (A-specific)" EXACT [EC:1.1.1.168] +synonym: "2-dehydropantoyl-lactone reductase (A-specific) activity" EXACT [EC:1.1.1.168] +synonym: "2-ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.168] +synonym: "2-oxopantoyl lactone reductase" BROAD [EC:1.1.1.168] +synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.168] +xref: EC:1.1.1.168 +xref: MetaCyc:1.1.1.168-RXN +is_a: GO:0036441 ! 2-dehydropantolactone reductase activity + +[Term] +id: GO:0047012 +name: sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one." [EC:1.1.1.170, MetaCyc:1.1.1.170-RXN] +synonym: "3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity" EXACT [] +synonym: "3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [EC:1.1.1.170] +synonym: "3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity" RELATED [EC:1.1.1.170] +synonym: "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170] +synonym: "sterol 4-alpha-carboxylic decarboxylase activity" RELATED [EC:1.1.1.170] +xref: EC:1.1.1.170 +xref: MetaCyc:1.1.1.170-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047013 +name: cholate 12-alpha dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH." [EC:1.1.1.176, RHEA:14129] +synonym: "12-alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.176] +synonym: "12alpha-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.176] +synonym: "12alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.176] +synonym: "12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity" BROAD [EC:1.1.1.176] +synonym: "NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.176] +synonym: "NADP-12alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.176] +xref: EC:1.1.1.176 +xref: KEGG_REACTION:R02793 +xref: MetaCyc:1.1.1.176-RXN +xref: RHEA:14129 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047014 +name: glycerol-3-phosphate 1-dehydrogenase [NADP+] activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH." [EC:1.1.1.177, RHEA:19773] +synonym: "glycerin-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.177] +synonym: "glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.177] +synonym: "L-glycerol 3-phosphate:NADP oxidoreductase activity" EXACT [EC:1.1.1.177] +synonym: "NADPH-dependent glycerin-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.177] +synonym: "sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.177] +xref: EC:1.1.1.177 +xref: KEGG_REACTION:R00845 +xref: MetaCyc:1.1.1.177-RXN +xref: RHEA:19773 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047015 +name: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA." [EC:1.1.1.178, MetaCyc:1.1.1.178-RXN] +synonym: "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.178] +synonym: "2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity" EXACT [EC:1.1.1.178] +synonym: "2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.178] +synonym: "2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.178] +xref: EC:1.1.1.178 +xref: MetaCyc:1.1.1.178-RXN +xref: RHEA:13281 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047016 +name: cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one." [EC:1.1.1.181, MetaCyc:1.1.1.181-RXN] +synonym: "3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity" EXACT [EC:1.1.1.181] +synonym: "3beta-hydroxy-delta5-C27-steroid oxidoreductase" BROAD [EC:1.1.1.181] +synonym: "cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity" EXACT [EC:1.1.1.181] +synonym: "cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.181] +xref: EC:1.1.1.181 +xref: MetaCyc:1.1.1.181-RXN +xref: RHEA:11896 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047017 +name: prostaglandin-F synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate." [EC:1.1.1.188, MetaCyc:1.1.1.188-RXN] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity" EXACT [EC:1.1.1.188] +synonym: "NADPH-dependent prostaglandin D2 11-keto reductase activity" EXACT [EC:1.1.1.188] +synonym: "PGD(2) 11-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "PGD2 11-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "PGF synthetase activity" EXACT [EC:1.1.1.188] +synonym: "PGF2alpha synthetase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin 11-keto reductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin 11-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin D2-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin F synthase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin F synthetase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D(2) 11-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D(2) 11-reductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D(2) ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D2 11-ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D2 11-reductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-D2 ketoreductase activity" EXACT [EC:1.1.1.188] +synonym: "prostaglandin-F synthetase activity" EXACT [EC:1.1.1.188] +synonym: "reductase, 15-hydroxy-11-oxoprostaglandin" EXACT [EC:1.1.1.188] +synonym: "synthetase, prostaglandin F2alpha" EXACT [EC:1.1.1.188] +xref: EC:1.1.1.188 +xref: MetaCyc:1.1.1.188-RXN +xref: RHEA:10140 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047018 +name: indole-3-acetaldehyde reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH." [EC:1.1.1.190, RHEA:14873] +synonym: "(indol-3-yl)ethanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.190] +synonym: "indole-3-ethanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.190] +synonym: "indoleacetaldehyde reductase activity" EXACT [EC:1.1.1.190] +xref: EC:1.1.1.190 +xref: KEGG_REACTION:R02679 +xref: MetaCyc:1.1.1.190-RXN +xref: RHEA:14873 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047019 +name: indole-3-acetaldehyde reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH." [EC:1.1.1.191, RHEA:17037] +synonym: "(indol-3-yl)ethanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.191] +synonym: "indole-3-ethanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.191] +synonym: "indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.191] +xref: EC:1.1.1.191 +xref: KEGG_REACTION:R02680 +xref: MetaCyc:1.1.1.191-RXN +xref: RHEA:17037 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047020 +name: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate." [EC:1.1.1.196, MetaCyc:1.1.1.196-RXN] +synonym: "(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.196] +synonym: "15-hydroxy PGD2 dehydrogenase activity" EXACT [EC:1.1.1.196] +synonym: "15-hydroxyprostaglandin dehydrogenase (NADP)" EXACT [EC:1.1.1.196] +synonym: "dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.196] +synonym: "dehydrogenase, prostaglandin D2" EXACT [EC:1.1.1.196] +synonym: "NADP-dependent 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] +synonym: "NADP-linked 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] +synonym: "NADP-linked prostaglandin D2 dehydrogenase activity" EXACT [EC:1.1.1.196] +synonym: "NADP-PGD2 dehydrogenase activity" EXACT [EC:1.1.1.196] +synonym: "NADP-specific 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] +synonym: "prostaglandin D2 dehydrogenase activity" EXACT [EC:1.1.1.196] +synonym: "prostaglandin-D 15-dehydrogenase (NADP(+)) activity" EXACT [EC:1.1.1.196] +synonym: "prostaglandin-D 15-dehydrogenase (NADP)" EXACT [EC:1.1.1.196] +synonym: "prostaglandin-D 15-dehydrogenase (NADP+) activity" EXACT [EC:1.1.1.196] +xref: EC:1.1.1.196 +xref: MetaCyc:1.1.1.196-RXN +xref: RHEA:20744 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047021 +name: 15-hydroxyprostaglandin dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH." [EC:1.1.1.197, RHEA:11636] +synonym: "(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.197] +synonym: "NADP-dependent 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] +synonym: "NADP-linked 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] +synonym: "NADP-specific 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] +synonym: "type II 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.197] +xref: EC:1.1.1.197 +xref: KEGG_REACTION:R04552 +xref: MetaCyc:1.1.1.197-RXN +xref: RHEA:11636 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047022 +name: 7-beta-hydroxysteroid dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid." [EC:1.1.1.201, MetaCyc:1.1.1.201-RXN] +synonym: "7beta-hydroxysteroid dehydrogenase (NADP+)" EXACT [EC:1.1.1.201] +synonym: "7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity" EXACT [EC:1.1.1.201] +synonym: "NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.201] +synonym: "NADP-dependent 7beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.201] +xref: EC:1.1.1.201 +xref: MetaCyc:1.1.1.201-RXN +xref: Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+) +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047023 +name: androsterone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione." [EC:1.1.1.209, MetaCyc:1.1.1.209-RXN] +synonym: "3(17)alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.209] +synonym: "3(or 17)-alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.209] +synonym: "3(or 17)alpha-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.209] +synonym: "3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity" BROAD [EC:1.1.1.209] +xref: EC:1.1.1.209 +xref: MetaCyc:1.1.1.209-RXN +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047024 +name: 5alpha-androstane-3beta,17beta-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH." [EC:1.1.1.210, RHEA:16297] +synonym: "3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210] +synonym: "3-beta-HSD activity" RELATED [EC:1.1.1.210] +synonym: "3beta(or 20alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210] +synonym: "3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity" BROAD [EC:1.1.1.210] +synonym: "3beta,20alpha-hydroxysteroid oxidoreductase activity" BROAD [EC:1.1.1.210] +synonym: "dehydrogenase, 3beta,20alpha-hydroxy steroid" BROAD [EC:1.1.1.210] +synonym: "progesterone reductase activity" RELATED [EC:1.1.1.210] +xref: EC:1.1.1.210 +xref: KEGG_REACTION:R04344 +xref: MetaCyc:1.1.1.210-RXN +xref: RHEA:16297 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047025 +name: 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein]." [EC:1.1.1.212, MetaCyc:1.1.1.212-RXN] +synonym: "(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.212] +synonym: "3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity" EXACT [] +synonym: "3-oxoacyl-ACP reductase (NADH) activity" EXACT [] +synonym: "3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity" EXACT [EC:1.1.1.212] +synonym: "3-oxoacyl-acyl-carrier-protein reductase (NADH)" EXACT [EC:1.1.1.212] +xref: EC:1.1.1.212 +xref: MetaCyc:1.1.1.212-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047026 +name: androsterone dehydrogenase (A-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+." [EC:1.1.1.213, MetaCyc:1.1.1.213-RXN] +synonym: "3-alpha-hydroxysteroid dehydrogenase (A-specific) activity" BROAD [EC:1.1.1.213] +synonym: "3alpha-hydroxysteroid dehydrogenase (A-specific)" BROAD [EC:1.1.1.213] +synonym: "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)" BROAD [EC:1.1.1.213] +xref: EC:1.1.1.213 +xref: MetaCyc:1.1.1.213-RXN +xref: Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(A-specific) +is_a: GO:0047023 ! androsterone dehydrogenase activity + +[Term] +id: GO:0047027 +name: benzyl-2-methyl-hydroxybutyrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH." [EC:1.1.1.217, RHEA:16405] +synonym: "benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.217] +synonym: "benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.217] +xref: EC:1.1.1.217 +xref: KEGG_REACTION:R04370 +xref: MetaCyc:1.1.1.217-RXN +xref: RHEA:16405 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047028 +name: 6-pyruvoyltetrahydropterin 2'-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin." [EC:1.1.1.220, MetaCyc:1.1.1.220-RXN] +synonym: "6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.1.1.220] +synonym: "6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity" EXACT [EC:1.1.1.220] +synonym: "6-pyruvoyl-tetrahydropterin 2'-reductase activity" EXACT [EC:1.1.1.220] +synonym: "6-pyruvoyltetrahydropterin reductase activity" EXACT [EC:1.1.1.220] +synonym: "6PPH4(2'-oxo) reductase activity" EXACT [EC:1.1.1.220] +synonym: "pyruvoyl-tetrahydropterin reductase activity" EXACT [EC:1.1.1.220] +xref: EC:1.1.1.220 +xref: MetaCyc:1.1.1.220-RXN +xref: RHEA:11772 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047029 +name: (R)-4-hydroxyphenyllactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate." [EC:1.1.1.222, MetaCyc:1.1.1.222-RXN] +synonym: "(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.222] +synonym: "(R)-aromatic lactate dehydrogenase activity" EXACT [EC:1.1.1.222] +synonym: "D-hydrogenase, D-aryllactate" EXACT [EC:1.1.1.222] +xref: EC:1.1.1.222 +xref: MetaCyc:1.1.1.222-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047030 +name: 4-hydroxycyclohexanecarboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH." [EC:1.1.1.226, RHEA:17429] +synonym: "trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity" EXACT [EC:1.1.1.226] +synonym: "trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.226] +xref: EC:1.1.1.226 +xref: KEGG_REACTION:R04307 +xref: MetaCyc:1.1.1.226-RXN +xref: RHEA:17429 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047031 +name: diethyl 2-methyl-3-oxosuccinate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH." [EC:1.1.1.229, RHEA:21008] +synonym: "diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.229] +xref: EC:1.1.1.229 +xref: KEGG_REACTION:R04387 +xref: MetaCyc:1.1.1.229-RXN +xref: RHEA:21008 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047032 +name: 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH." [EC:1.1.1.230, RHEA:20816] +synonym: "3alpha-hydroxyglycyrrhetinate dehydrogenase activity" EXACT [EC:1.1.1.230] +synonym: "3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.230] +xref: EC:1.1.1.230 +xref: KEGG_REACTION:R04099 +xref: MetaCyc:1.1.1.230-RXN +xref: RHEA:20816 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047033 +name: 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH." [EC:1.1.1.231, RHEA:21420] +synonym: "(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.231] +synonym: "NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.231] +synonym: "NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity" EXACT [EC:1.1.1.231] +synonym: "PG I2 dehydrogenase activity" EXACT [EC:1.1.1.231] +synonym: "prostacyclin dehydrogenase activity" EXACT [EC:1.1.1.231] +xref: EC:1.1.1.231 +xref: KEGG_REACTION:R03520 +xref: MetaCyc:1.1.1.231-RXN +xref: RHEA:21420 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047034 +name: 15-hydroxyicosatetraenoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate." [EC:1.1.1.232, MetaCyc:1.1.1.232-RXN] +synonym: "(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity" EXACT [EC:1.1.1.232] +synonym: "15-hydroxyeicosatetraenoate dehydrogenase activity" EXACT [EC:1.1.1.232] +xref: EC:1.1.1.232 +xref: MetaCyc:1.1.1.232-RXN +xref: Reactome:R-HSA-2161789 "15S-HETE is oxidised to 15-oxoETE by 15-HEDH" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047035 +name: testosterone dehydrogenase (NAD+) activity +namespace: molecular_function +alt_id: GO:0050327 +def: "Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH." [EC:1.1.1.239, MetaCyc:1.1.1.239-RXN] +synonym: "17-beta-HSD activity" BROAD [EC:1.1.1.63] +synonym: "17-ketoreductase activity" BROAD [EC:1.1.1.63] +synonym: "17beta-HSD" RELATED [EC:1.1.1.63] +synonym: "17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity" EXACT [EC:1.1.1.63] +synonym: "3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity" BROAD [EC:1.1.1.239] +synonym: "3alpha(17beta)-HSD" RELATED [EC:1.1.1.239] +synonym: "3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)" BROAD [EC:1.1.1.239] +synonym: "3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity" BROAD [EC:1.1.1.239] +synonym: "3alpha,17beta-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.239] +synonym: "testosterone 17-beta-dehydrogenase (NAD+) activity" EXACT [] +synonym: "testosterone 17b-dehydrogenase activity" EXACT [] +synonym: "testosterone 17beta-dehydrogenase activity" EXACT [EC:1.1.1.63] +xref: EC:1.1.1.239 +xref: KEGG_REACTION:R01836 +xref: MetaCyc:1.1.1.239-RXN +xref: MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN +xref: RHEA:14929 +xref: Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+) +is_a: GO:0030283 ! testosterone dehydrogenase [NAD(P)] activity + +[Term] +id: GO:0047036 +name: codeinone reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH." [EC:1.1.1.247, RHEA:19209] +synonym: "codeine:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.247] +xref: EC:1.1.1.247 +xref: KEGG_REACTION:R05124 +xref: MetaCyc:1.1.1.247-RXN +xref: RHEA:19209 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047037 +name: salutaridine reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine." [EC:1.1.1.248, RHEA:10108] +synonym: "salutaridinol:NADP+ 7-oxidoreductase activity" EXACT [EC:1.1.1.248] +xref: EC:1.1.1.248 +xref: KEGG_REACTION:R04697 +xref: MetaCyc:1.1.1.248-RXN +xref: RHEA:10108 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047038 +name: D-arabinitol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH." [EC:1.1.1.250, RHEA:17389] +synonym: "D-arabinitol 2-dehydrogenase (ribulose-forming) activity" EXACT [EC:1.1.1.250] +synonym: "D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)" EXACT [EC:1.1.1.250] +xref: EC:1.1.1.250 +xref: KEGG_REACTION:R07134 +xref: MetaCyc:1.1.1.250-RXN +xref: RHEA:17389 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047039 +name: tetrahydroxynaphthalene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol." [EC:1.1.1.252, MetaCyc:1.1.1.252-RXN] +synonym: "scytalone:NADP+ delta5-oxidoreductase activity" EXACT [EC:1.1.1.252] +synonym: "T4HN reductase activity" EXACT [EC:1.1.1.252] +xref: EC:1.1.1.252 +xref: MetaCyc:1.1.1.252-RXN +xref: RHEA:21908 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047040 +name: pteridine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH." [EC:1.5.1.33, RHEA:19509] +comment: Note that this function was formerly EC:1.1.1.253. +synonym: "5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.33] +synonym: "dihydrobiopterin reduction" RELATED [] +synonym: "pteridine reductase 1 activity" NARROW [EC:1.5.1.33e] +synonym: "PTR1" RELATED [EC:1.5.1.33] +synonym: "ptr1 activity" NARROW [EC:1.5.1.33e] +xref: EC:1.5.1.33 +xref: KEGG_REACTION:R01812 +xref: MetaCyc:1.1.1.253-RXN +xref: RHEA:19509 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047041 +name: (S)-carnitine 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH." [EC:1.1.1.254, RHEA:11556] +synonym: "(S)-carnitine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.254] +synonym: "D-carnitine dehydrogenase activity" EXACT [EC:1.1.1.254] +xref: EC:1.1.1.254 +xref: KEGG_REACTION:R01921 +xref: MetaCyc:1.1.1.254-RXN +xref: RHEA:11556 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047042 +name: androsterone dehydrogenase (B-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+." [EC:1.1.1.50, MetaCyc:1.1.1.50-RXN] +synonym: "3-alpha-HSD activity" RELATED [EC:1.1.1.50] +synonym: "3-alpha-hydroxysteroid dehydrogenase (B-specific) activity" BROAD [EC:1.1.1.50] +synonym: "3alpha-HSD" RELATED [EC:1.1.1.50] +synonym: "3alpha-hydroxysteroid dehydrogenase (B-specific)" BROAD [EC:1.1.1.50] +synonym: "3alpha-hydroxysteroid oxidoreductase activity" BROAD [EC:1.1.1.50] +synonym: "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)" BROAD [EC:1.1.1.50] +synonym: "hydroxyprostaglandin dehydrogenase activity" RELATED [EC:1.1.1.50] +synonym: "sterognost 3alpha" RELATED [EC:1.1.1.50] +xref: EC:1.1.1.50 +xref: MetaCyc:1.1.1.50-RXN +xref: Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(B-specific) +is_a: GO:0047023 ! androsterone dehydrogenase activity + +[Term] +id: GO:0047043 +name: 3-alpha-hydroxycholanate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH." [EC:1.1.1.52, RHEA:19585] +synonym: "3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.52] +synonym: "3alpha-hydroxycholanate dehydrogenase activity" EXACT [EC:1.1.1.52] +synonym: "alpha-hydroxy-cholanate dehydrogenase activity" EXACT [EC:1.1.1.52] +xref: EC:1.1.1.52 +xref: KEGG_REACTION:R04139 +xref: MetaCyc:1.1.1.52-RXN +xref: RHEA:19585 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047044 +name: androstan-3-alpha,17-beta-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+." [EC:1.1.1.53, MetaCyc:1.1.1.53-RXN] +synonym: "(R)-20-hydroxysteroid dehydrogenase activity" RELATED [EC:1.1.1.53] +synonym: "20beta-HSD" RELATED [EC:1.1.1.53] +synonym: "20beta-hydroxysteroid dehydrogenase activity" RELATED [EC:1.1.1.53] +synonym: "3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.53] +synonym: "3alpha(or 20beta)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.53] +synonym: "3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity" BROAD [EC:1.1.1.53] +synonym: "3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity" BROAD [EC:1.1.1.53] +synonym: "cortisone reductase activity" RELATED [EC:1.1.1.53] +synonym: "dehydrogenase, 20beta-hydroxy steroid" BROAD [EC:1.1.1.53] +synonym: "delta4-3-ketosteroid hydrogenase activity" BROAD [EC:1.1.1.53] +synonym: "NADH-20beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.53] +xref: EC:1.1.1.53 +xref: MetaCyc:1.1.1.53-RXN +xref: RHEA:22400 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047045 +name: testosterone 17-beta-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione." [EC:1.1.1.64, MetaCyc:1.1.1.64-RXN] +synonym: "17-ketoreductase activity" BROAD [EC:1.1.1.64] +synonym: "17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity" EXACT [EC:1.1.1.64] +synonym: "NADP-dependent testosterone-17beta-oxidoreductase activity" EXACT [EC:1.1.1.64] +synonym: "testosterone 17beta-dehydrogenase (NADP+)" EXACT [EC:1.1.1.64] +xref: EC:1.1.1.64 +xref: KEGG_REACTION:R01838 +xref: MetaCyc:1.1.1.64-RXN +xref: RHEA:14981 +xref: Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+) +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047046 +name: homoisocitrate dehydrogenase activity +namespace: molecular_function +alt_id: GO:0047984 +def: "Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate." [EC:1.1.1.155, EC:1.1.1.87, MetaCyc:1.1.1.87-RXN] +comment: Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical. +synonym: "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.87] +synonym: "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] +synonym: "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] +synonym: "2-hydroxy-3-carboxyadipate dehydrogenase activity" EXACT [EC:1.1.1.87] +synonym: "3-carboxy-2-hydroxyadipate dehydrogenase activity" EXACT [] +synonym: "3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.87] +synonym: "3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] +synonym: "homoisocitric dehydrogenase activity" EXACT [EC:1.1.1.87] +xref: EC:1.1.1.87 +xref: MetaCyc:1.1.1.87-RXN +xref: RHEA:11900 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047047 +name: oxaloglycolate reductase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate." [EC:1.1.1.92, MetaCyc:1.1.1.92-RXN] +synonym: "D-glycerate:NAD(P)+ oxidoreductase (carboxylating)" EXACT [EC:1.1.1.92] +xref: EC:1.1.1.92 +xref: MetaCyc:1.1.1.92-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047048 +name: 3-hydroxybenzyl-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH." [EC:1.1.1.97, RHEA:22340] +synonym: "3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.97] +synonym: "m-hydroxybenzyl alcohol (NADP) dehydrogenase activity" EXACT [EC:1.1.1.97] +synonym: "m-hydroxybenzyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.97] +synonym: "m-hydroxybenzylalcohol dehydrogenase activity" EXACT [EC:1.1.1.97] +xref: EC:1.1.1.97 +xref: KEGG_REACTION:R04136 +xref: MetaCyc:1.1.1.97-RXN +xref: RHEA:22340 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047049 +name: (R)-2-hydroxy-fatty acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH." [EC:1.1.1.98, RHEA:15949] +synonym: "(R)-2-hydroxy-fatty-acid dehydrogenase activity" EXACT [] +synonym: "(R)-2-hydroxystearate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.98] +synonym: "2-hydroxy fatty acid oxidase" BROAD [EC:1.1.1.98] +synonym: "D-2-hydroxy fatty acid dehydrogenase activity" EXACT [EC:1.1.1.98] +xref: EC:1.1.1.98 +xref: KEGG_REACTION:R03021 +xref: MetaCyc:1.1.1.98-RXN +xref: RHEA:15949 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047050 +name: (S)-2-hydroxy-fatty acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH." [EC:1.1.1.99, RHEA:11384] +synonym: "(S)-2-hydroxy-fatty-acid dehydrogenase activity" EXACT [] +synonym: "(S)-2-hydroxystearate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.99] +synonym: "2-hydroxy fatty acid oxidase" BROAD [EC:1.1.1.99] +synonym: "dehydrogenase, L-2-hydroxy fatty acid" EXACT [EC:1.1.1.99] +synonym: "L-2-hydroxy fatty acid dehydrogenase activity" EXACT [EC:1.1.1.99] +xref: EC:1.1.1.99 +xref: KEGG_REACTION:R03022 +xref: MetaCyc:1.1.1.99-RXN +xref: RHEA:11384 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047051 +name: D-lactate dehydrogenase (cytochrome c-553) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 ferricytochrome C-553 + D-lactate = 2 ferrocytochrome C-553 + pyruvate." [EC:1.1.2.5, MetaCyc:1.1.2.5-RXN] +synonym: "(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity" EXACT [EC:1.1.2.5] +xref: EC:1.1.2.5 +xref: MetaCyc:1.1.2.5-RXN +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0047052 +name: (S)-stylopine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-cheilanthifoline + H(+) + NADPH + O(2) = (S)-stylopine + 2 H(2)O + NADP(+)." [EC:1.14.19.64, RHEA:13773] +synonym: "(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity" EXACT [EC:1.14.19.64] +synonym: "(S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.19.64] +xref: EC:1.14.19.64 +xref: KEGG_REACTION:R04690 +xref: MetaCyc:1.1.3.32-RXN +xref: RHEA:13773 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0047053 +name: (S)-cheilanthifoline synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-scoulerine + H(+) + NADPH + O(2) = (S)-cheilanthifoline + 2 H(2)O + NADP(+)." [EC:1.14.19.65, RHEA:20485] +synonym: "(S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity" EXACT [] +synonym: "(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.19.65] +xref: EC:1.14.19.65 +xref: KEGG_REACTION:R03834 +xref: MetaCyc:1.14.21.2-RXN +xref: RHEA:20485 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0047054 +name: berbamunine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine." [EC:1.14.19.66, MetaCyc:1.1.3.34-RXN] +synonym: "(S)-N-methylcoclaurine oxidase (C-O phenol-coupling) activity" EXACT [EC:1.14.19.66] +synonym: "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (C-O phenol-coupling)" EXACT [EC:1.14.19.66] +xref: EC:1.14.19.66 +xref: MetaCyc:1.1.3.34-RXN +xref: RHEA:23576 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0047055 +name: salutaridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-reticuline + H(+) + NADPH + O(2) = 2 H(2)O + NADP(+) + salutaridine." [EC:1.14.19.67, RHEA:17713] +synonym: "(R)-reticuline oxidase (C-C phenol-coupling) activity" EXACT [EC:1.14.19.67] +synonym: "(R)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling)" EXACT [EC:1.14.19.67] +xref: EC:1.14.19.67 +xref: KEGG_REACTION:R04696 +xref: MetaCyc:1.1.3.35-RXN +xref: RHEA:17713 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0047056 +name: (S)-canadine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-tetrahydrocolumbamine + H(+) + NADPH + O(2) = (S)-canadine + 2 H(2)O + NADP(+)." [EC:1.14.19.68, RHEA:21456] +synonym: "(S)-tetrahydroberberine synthase activity" EXACT [EC:1.14.19.68] +synonym: "(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity" EXACT [EC:1.14.19.68] +synonym: "(S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.19.68] +xref: EC:1.14.19.68 +xref: KEGG_REACTION:R04400 +xref: MetaCyc:1.1.3.36-RXN +xref: RHEA:21456 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0047057 +name: vitamin-K-epoxide reductase (warfarin-sensitive) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol." [EC:1.1.4.1, MetaCyc:1.1.4.1-RXN] +synonym: "2-methyl-3-phytyl-1,4-naphthoquinone:oxidized-dithiothreitol oxidoreductase activity" EXACT [EC:1.1.4.1] +synonym: "phylloquinone epoxide reductase activity" EXACT [EC:1.1.4.1] +synonym: "vitamin K1 epoxide reductase activity" NARROW [EC:1.1.4.1] +xref: EC:1.1.4.1 +xref: MetaCyc:1.1.4.1-RXN +xref: Reactome:R-HSA-159790 "VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)" +xref: Reactome:R-HSA-6806647 "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)" +xref: RHEA:13817 +is_a: GO:0016900 ! oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor + +[Term] +id: GO:0047058 +name: vitamin-K-epoxide reductase (warfarin-insensitive) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol." [EC:1.1.4.2, MetaCyc:1.1.4.2-RXN] +synonym: "3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase activity" EXACT [EC:1.1.4.2] +synonym: "vitamin K 2,3-epoxide reductase activity" EXACT [EC:1.1.4.2] +xref: EC:1.1.4.2 +xref: MetaCyc:1.1.4.2-RXN +xref: RHEA:21560 +is_a: GO:0016900 ! oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor + +[Term] +id: GO:0047059 +name: polyvinyl alcohol dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+." [EC:1.1.2.6] +synonym: "polyvinyl alcohol:ferricytochrome-c oxidoreductase activity" EXACT systematic_synonym [EC:1.1.2.6] +synonym: "polyvinyl-alcohol:(acceptor) oxidoreductase activity" BROAD [EC:1.1.99.23] +synonym: "polyvinyl-alcohol:acceptor oxidoreductase activity" BROAD [EC:1.1.99.23] +synonym: "PVA dehydrogenase activity" BROAD [EC:1.1.99.23] +xref: EC:1.1.2.6 +xref: KEGG_REACTION:R03136 +xref: MetaCyc:RXN-11316 +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0047060 +name: (R)-pantolactone dehydrogenase (flavin) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2)." [EC:1.1.99.27, RHEA:21004] +synonym: "(R)-pantolactone:acceptor oxidoreductase (flavin-containing)" EXACT [EC:1.1.99.27] +synonym: "(R)-pantoyllactone dehydrogenase (flavin) activity" EXACT [EC:1.1.99.27] +synonym: "2-dehydropantolactone reductase (flavin) activity" EXACT [EC:1.1.99.27] +synonym: "2-dehydropantoyl-lactone reductase (flavin) activity" EXACT [EC:1.1.99.27] +xref: EC:1.1.99.27 +xref: KEGG_REACTION:R03156 +xref: MetaCyc:1.1.99.27-RXN +xref: RHEA:21004 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047061 +name: glucose-fructose oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone." [EC:1.1.99.28, RHEA:20637] +synonym: "D-glucose:D-fructose oxidoreductase activity" EXACT [EC:1.1.99.28] +xref: EC:1.1.99.28 +xref: KEGG_REACTION:R00874 +xref: MetaCyc:1.1.99.28-RXN +xref: RHEA:20637 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047062 +name: trans-acenaphthene-1,2-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH." [EC:1.10.1.1, RHEA:22184] +synonym: "(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.10.1.1] +synonym: "trans-1,2-acenaphthenediol dehydrogenase activity" EXACT [EC:1.10.1.1] +xref: EC:1.10.1.1 +xref: KEGG_REACTION:R04059 +xref: MetaCyc:1.10.1.1-RXN +xref: RHEA:22184 +is_a: GO:0016680 ! oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor + +[Term] +id: GO:0047063 +name: L-ascorbate-cytochrome-b5 reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate." [EC:1.10.2.1, RHEA:18677] +synonym: "ascorbate-cytochrome b5 reductase activity" EXACT [EC:1.10.2.1] +synonym: "L-ascorbate:ferricytochrome-b5 oxidoreductase activity" EXACT [EC:1.10.2.1] +xref: EC:1.10.2.1 +xref: MetaCyc:1.10.2.1-RXN +is_a: GO:0016681 ! oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor + +[Term] +id: GO:0047064 +name: sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O." [EC:1.21.3.4, RHEA:24092] +synonym: "sulochrin oxidase activity" EXACT [EC:1.21.3.4] +synonym: "sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)" EXACT [EC:1.21.3.4] +xref: EC:1.21.3.4 +xref: KEGG_REACTION:R00060 +xref: MetaCyc:1.10.3.7-RXN +xref: RHEA:24092 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0047065 +name: sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O." [EC:1.21.3.5, RHEA:22616] +synonym: "sulochrin oxidase activity" BROAD [EC:1.21.3.5] +synonym: "sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)" EXACT [EC:1.21.3.5] +xref: EC:1.21.3.5 +xref: KEGG_REACTION:R00061 +xref: MetaCyc:1.10.3.8-RXN +xref: RHEA:22616 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0047066 +name: phospholipid-hydroperoxide glutathione peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione." [EC:1.11.1.12, MetaCyc:1.11.1.12-RXN] +synonym: "glutathione:lipid-hydroperoxide oxidoreductase activity" EXACT [EC:1.11.1.12] +synonym: "hydroperoxide glutathione peroxidase activity" EXACT [EC:1.11.1.12] +synonym: "peroxidation-inhibiting protein activity" RELATED [EC:1.11.1.12] +synonym: "peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)" EXACT [EC:1.11.1.12] +synonym: "PHGPX" RELATED [EC:1.11.1.12] +synonym: "phospholipid hydroperoxide glutathione peroxidase activity" EXACT [EC:1.11.1.12] +xref: EC:1.11.1.12 +xref: MetaCyc:1.11.1.12-RXN +xref: Reactome:R-HSA-9018868 "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE" +xref: Reactome:R-HSA-9018895 "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE" +xref: Reactome:R-HSA-9020271 "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA" +xref: Reactome:R-HSA-9020273 "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA" +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor + +[Term] +id: GO:0047067 +name: hydrogen:quinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone." [EC:1.12.5.1, RHEA:18641] +synonym: "hydrogen-ubiquinone oxidoreductase activity" EXACT [EC:1.12.5.1] +synonym: "hydrogen:menaquinone oxidoreductase activity" EXACT [EC:1.12.5.1] +synonym: "membrane-bound hydrogenase activity" NARROW [EC:1.12.5.1] +synonym: "quinone-reactive Ni/Fe-hydrogenase activity" RELATED [EC:1.12.5.1] +xref: EC:1.12.5.1 +xref: KEGG_REACTION:R02965 +xref: MetaCyc:1.12.5.1-RXN +xref: RHEA:18641 +is_a: GO:0046994 ! oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor + +[Term] +id: GO:0047068 +name: N5,N10-methenyltetrahydromethanopterin hydrogenase activity +namespace: molecular_function +alt_id: GO:0016947 +def: "Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+)." [EC:1.12.98.2, RHEA:20017] +synonym: "5,10-methenyltetrahydromethanopterin hydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "H(2)-dependent methylene-H(4)MPT dehydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "H2-dependent methylene-H4MPT dehydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] +synonym: "hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] +synonym: "hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] +synonym: "N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity" EXACT [EC:1.12.98.2] +synonym: "N5,N10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [] +synonym: "nonmetal hydrogenase activity" RELATED [EC:1.12.98.2] +xref: EC:1.12.98.2 +xref: KEGG_REACTION:R04455 +xref: MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN +xref: RHEA:20017 +is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors + +[Term] +id: GO:0047069 +name: 7,8-dihydroxykynurenate 8,8a-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)." [EC:1.13.11.10, RHEA:23400] +synonym: "7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity" EXACT [EC:1.13.11.10] +synonym: "7,8-dihydroxykynurenate oxygenase activity" EXACT [EC:1.13.11.10] +synonym: "7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.10] +synonym: "7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.10] +xref: EC:1.13.11.10 +xref: KEGG_REACTION:R03253 +xref: MetaCyc:1.13.11.10-RXN +xref: RHEA:23400 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047070 +name: 3-carboxyethylcatechol 2,3-dioxygenase activity +namespace: molecular_function +alt_id: GO:0008669 +def: "Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate." [EC:1.13.11.16, MetaCyc:1.13.11.16-RXN] +synonym: "2,3-dihydroxy-beta-phenylpropionate oxygenase activity" EXACT [EC:1.13.11.16] +synonym: "2,3-dihydroxy-beta-phenylpropionic dioxygenase activity" EXACT [EC:1.13.11.16] +synonym: "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.16] +synonym: "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.16] +xref: EC:1.13.11.16 +xref: MetaCyc:1.13.11.16-RXN +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047071 +name: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+)." [EC:1.13.11.25, RHEA:21352] +synonym: "3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.25] +synonym: "3-alkylcatechol 2,3-dioxygenase activity" EXACT [EC:1.13.11.25] +synonym: "steroid 4,5-dioxygenase activity" BROAD [EC:1.13.11.25] +xref: EC:1.13.11.25 +xref: KEGG_REACTION:R04597 +xref: MetaCyc:1.13.11.25-RXN +xref: RHEA:21352 +xref: UM-BBD_reactionID:r1151 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047072 +name: 2,3-dihydroxybenzoate 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+)." [EC:1.13.11.28, RHEA:15369] +synonym: "2,3-dihydroxybenzoate 2,3-oxygenase activity" EXACT [EC:1.13.11.28] +synonym: "2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.28] +xref: EC:1.13.11.28 +xref: KEGG_REACTION:R01506 +xref: MetaCyc:1.13.11.28-RXN +xref: RHEA:15369 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047073 +name: 2,4'-dihydroxyacetophenone dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+)." [EC:1.13.11.41, RHEA:24416] +synonym: "(4-hydroxybenzoyl)methanol oxygenase activity" EXACT [EC:1.13.11.41] +synonym: "2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)" EXACT [EC:1.13.11.41] +xref: EC:1.13.11.41 +xref: KEGG_REACTION:R01305 +xref: MetaCyc:1.13.11.41-RXN +xref: RHEA:24416 +xref: UM-BBD_reactionID:r1410 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047074 +name: 4-hydroxycatechol 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate." [EC:1.13.11.-, MetaCyc:R308-RXN] +xref: EC:1.13.11 +xref: MetaCyc:RXN-10137 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047075 +name: 2,5-dihydroxypyridine 5,6-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate." [EC:1.13.11.9, MetaCyc:1.13.11.9-RXN] +synonym: "2,5-dihydroxypyridine oxygenase activity" EXACT [EC:1.13.11.9] +synonym: "2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity" EXACT [EC:1.13.11.9] +synonym: "pyridine-2,5-diol dioxygenase activity" EXACT [EC:1.13.11.9] +xref: EC:1.13.11.9 +xref: MetaCyc:1.13.11.9-RXN +xref: RHEA:27522 +xref: UM-BBD_reactionID:r1443 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047077 +name: Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin." [EC:1.13.12.7, MetaCyc:1.13.12.7-RXN] +synonym: "firefly luciferase activity" EXACT [EC:1.13.12.7] +synonym: "firefly luciferin luciferase activity" EXACT [EC:1.13.12.7] +synonym: "luciferase (firefly luciferin)" EXACT [EC:1.13.12.7] +synonym: "luciferase activity" BROAD [EC:1.13.12.7] +synonym: "Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)" EXACT [EC:1.13.12.7] +synonym: "Photinus pyralis luciferase activity" EXACT [EC:1.13.12.7] +synonym: "Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)" EXACT [EC:1.13.12.7] +synonym: "Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)" EXACT [EC:1.13.12.7] +xref: EC:1.13.12.7 +xref: MetaCyc:1.13.12.7-RXN +xref: RHEA:10732 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0047078 +name: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate." [EC:1.13.11.47, MetaCyc:1.13.11.47-RXN] +synonym: "(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] +synonym: "1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity" EXACT [] +synonym: "3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)" EXACT [EC:1.13.11.47] +synonym: "3-hydroxy-4(1H)-one, 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] +synonym: "3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] +synonym: "quinoline-3,4-diol 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] +xref: EC:1.13.11.47 +xref: MetaCyc:1.13.11.47-RXN +xref: RHEA:17949 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047079 +name: deoxyuridine 1'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil." [EC:1.14.11.10, RHEA:23316] +synonym: "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)" EXACT [EC:1.14.11.10] +synonym: "pyrimidine-deoxynucleoside 1'-dioxygenase activity" BROAD [EC:1.14.11.10] +synonym: "pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity" BROAD [EC:1.14.11.10] +xref: EC:1.14.11.10 +xref: KEGG_REACTION:R02486 +xref: MetaCyc:1.14.11.10-RXN +xref: RHEA:23316 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0047080 +name: deoxyuridine 2'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine." [EC:1.14.11.3, RHEA:21076] +synonym: "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)" EXACT [EC:1.14.11.3] +synonym: "deoxyuridine 2'-hydroxylase activity" EXACT [EC:1.14.11.3] +synonym: "pyrimidine deoxyribonucleoside 2'-hydroxylase activity" BROAD [EC:1.14.11.3] +synonym: "pyrimidine-deoxynucleoside 2'-dioxygenase activity" BROAD [EC:1.14.11.3] +synonym: "pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity" BROAD [EC:1.14.11.3] +synonym: "thymidine 2'-dioxygenase activity" NARROW [EC:1.14.11.3] +synonym: "thymidine 2'-hydroxylase activity" RELATED [EC:1.14.11.3] +synonym: "thymidine 2-oxoglutarate dioxygenase activity" RELATED [EC:1.14.11.3] +synonym: "thymidine dioxygenase activity" RELATED [EC:1.14.11.3] +xref: EC:1.14.11.3 +xref: KEGG_REACTION:R01879 +xref: MetaCyc:1.14.11.3-RXN +xref: RHEA:21076 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0047081 +name: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate." [EC:1.14.13.242, MetaCyc:1.14.12.4-RXN] +synonym: "2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity" EXACT [EC:1.14.13.242] +synonym: "3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (decyclizing)" EXACT [EC:1.14.13.242] +synonym: "3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity" EXACT [EC:1.14.13.242] +synonym: "methylhydroxypyridine carboxylate dioxygenase activity" EXACT [EC:1.14.13.242] +synonym: "methylhydroxypyridinecarboxylate oxidase activity" EXACT [EC:1.14.13.242] +xref: EC:1.14.13.242 +xref: MetaCyc:1.14.12.4-RXN +xref: RHEA:10864 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0047082 +name: 3,9-dihydroxypterocarpan 6a-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol." [EC:1.14.14.93, RHEA:15321] +synonym: "(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)" EXACT [EC:1.14.14.93] +synonym: "3,9-dihydroxypterocarpan 6a-hydroxylase activity" EXACT [] +synonym: "3,9-dihydroxypterocarpan 6alpha-monooxygenase" RELATED [] +xref: EC:1.14.14.93 +xref: KEGG_REACTION:R03452 +xref: MetaCyc:RXN-4505 +xref: RHEA:15321 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047083 +name: 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate." [EC:1.14.14.96, MetaCyc:1.14.13.36-RXN] +synonym: "5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity" EXACT [] +synonym: "coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity" EXACT [EC:1.14.14.96] +synonym: "trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.14.96] +xref: EC:1.14.14.96 +xref: MetaCyc:1.14.13.36-RXN +xref: RHEA:16265 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047084 +name: methyltetrahydroprotoberberine 14-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine." [EC:1.14.14.97, MetaCyc:1.14.13.37-RXN] +synonym: "(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity" EXACT [EC:1.14.14.97] +synonym: "(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity" EXACT [EC:1.14.14.97] +synonym: "(S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)" EXACT [EC:1.14.14.97] +synonym: "methyltetrahydroprotoberberine 14-hydroxylase activity" EXACT [] +xref: EC:1.14.14.97 +xref: MetaCyc:1.14.13.37-RXN +xref: RHEA:23684 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047085 +name: hydroxyphenylacetonitrile 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+)." [RHEA:23740] +synonym: "4-hydroxyphenylacetonitrile hydroxylase activity" EXACT [] +synonym: "4-hydroxyphenylacetonitrile monooxygenase activity" EXACT [] +synonym: "4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [] +xref: KEGG_REACTION:R02708 +xref: MetaCyc:1.14.13.42-RXN +xref: RHEA:23740 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047086 +name: ketosteroid monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate." [EC:1.14.13.54, MetaCyc:1.14.13.54-RXN] +synonym: "17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)" EXACT [EC:1.14.13.54] +synonym: "androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)" EXACT [EC:1.14.13.54] +synonym: "ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)" EXACT [EC:1.14.13.54] +synonym: "progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)" EXACT [EC:1.14.13.54] +synonym: "steroid-ketone monooxygenase activity" EXACT [EC:1.14.13.54] +xref: EC:1.14.13.54 +xref: MetaCyc:1.14.13.54-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047087 +name: protopine 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+)." [EC:1.14.14.98, RHEA:22644] +synonym: "protopine 6-hydroxylase activity" EXACT [] +synonym: "protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.14.98] +xref: EC:1.14.14.98 +xref: KEGG_REACTION:R04699 +xref: MetaCyc:1.14.13.55-RXN +xref: RHEA:22644 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047088 +name: dihydrosanguinarine 10-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+)." [EC:1.14.14.100, RHEA:10528] +synonym: "dihydrosanguinarine 10-hydroxylase activity" EXACT [] +synonym: "dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)" EXACT [EC:1.14.14.100] +xref: EC:1.14.14.100 +xref: KEGG_REACTION:R04702 +xref: MetaCyc:1.14.13.56-RXN +xref: RHEA:10528 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047089 +name: dihydrochelirubine 12-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+)." [EC:1.14.14.101, RHEA:10156] +synonym: "dihydrochelirubine 12-hydroxylase activity" EXACT [] +synonym: "dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)" EXACT [EC:1.14.14.101] +xref: EC:1.14.14.101 +xref: KEGG_REACTION:R04708 +xref: MetaCyc:1.14.13.57-RXN +xref: RHEA:10156 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047090 +name: benzoyl-CoA 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+)." [EC:1.14.13.58, RHEA:23216] +synonym: "benzoyl-CoA 3-hydroxylase activity" EXACT [] +synonym: "benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.58] +xref: EC:1.14.13.58 +xref: KEGG_REACTION:R02449 +xref: MetaCyc:1.14.13.58-RXN +xref: RHEA:23216 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047091 +name: L-lysine 6-monooxygenase (NADPH) activity +namespace: molecular_function +alt_id: GO:0008739 +def: "Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+)." [EC:1.14.13.59, RHEA:23228] +comment: Note that EC:1.13.12.10 was merged into this term. +synonym: "L-lysine 6-monooxygenase activity" EXACT [] +synonym: "L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.59] +synonym: "lysine N(6)-hydroxylase activity" EXACT [EC:1.14.13.59] +synonym: "lysine N6-hydroxylase activity" EXACT [] +xref: EC:1.14.13.59 +xref: KEGG_REACTION:R00448 +xref: MetaCyc:1.14.13.59-RXN +xref: RHEA:23228 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047092 +name: 27-hydroxycholesterol 7-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol." [EC:1.14.14.29, MetaCyc:1.14.13.60-RXN, RHEA:24308] +synonym: "27-hydroxycholesterol 7-alpha-hydroxylase activity" EXACT [EC:1.14.14.29] +synonym: "27-hydroxycholesterol 7a-hydroxylase activity" EXACT [] +synonym: "27-hydroxycholesterol 7alpha-hydroxylase activity" EXACT [EC:1.14.14.29] +synonym: "27-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.14.29] +synonym: "27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [] +xref: EC:1.14.14.29 +xref: MetaCyc:1.14.13.60-RXN +xref: RHEA:24308 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047093 +name: 4-hydroxyquinoline 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol." [EC:1.14.13.62, RHEA:19325] +synonym: "1-H-4-oxoquinoline 3-monooxygenase activity" EXACT [EC:1.14.13.62] +synonym: "quinolin-4(1H)-one 3-monooxygenase activity" EXACT [EC:1.14.13.62] +synonym: "quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)" EXACT [EC:1.14.13.62] +xref: EC:1.14.13.62 +xref: KEGG_REACTION:R05154 +xref: MetaCyc:1.14.13.62-RXN +xref: RHEA:19325 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047094 +name: 3-hydroxyphenylacetate 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate." [EC:1.14.13.63, MetaCyc:1.14.13.63-RXN] +synonym: "3-hydroxyphenylacetate 6-monooxygenase activity" EXACT [EC:1.14.13.63] +synonym: "3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.63] +xref: EC:1.14.13.63 +xref: MetaCyc:1.14.13.63-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047095 +name: 2-hydroxycyclohexanone 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+)." [EC:1.14.13.66, RHEA:33283] +synonym: "2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)" EXACT [EC:1.14.13.66] +xref: EC:1.14.13.66 +xref: KEGG_REACTION:R03281 +xref: MetaCyc:1.14.13.66-RXN +xref: RHEA:33283 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047096 +name: androst-4-ene-3,17-dione monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone." [EC:1.14.99.12, RHEA:22696] +synonym: "4-androstene-3,17-dione monooxygenase activity" EXACT [] +synonym: "androst-4-ene-3,17-dione 17-oxidoreductase activity" EXACT [EC:1.14.99.12] +synonym: "androst-4-ene-3,17-dione hydroxylase activity" EXACT [EC:1.14.99.12] +synonym: "androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing)" EXACT [EC:1.14.99.12] +synonym: "androstene-3,17-dione hydroxylase activity" EXACT [] +synonym: "androstenedione monooxygenase activity" EXACT [EC:1.14.99.12] +xref: EC:1.14.99.12 +xref: KEGG_REACTION:R01833 +xref: MetaCyc:1.14.99.12-RXN +xref: RHEA:22696 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0047097 +name: phylloquinone monooxygenase (2,3-epoxidizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O." [EC:1.14.99.20, RHEA:16745] +synonym: "phylloquinone epoxidase activity" EXACT [EC:1.14.99.20] +synonym: "phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)" EXACT [EC:1.14.99.20] +synonym: "vitamin K 2,3-epoxidase activity" EXACT [EC:1.14.99.20] +synonym: "vitamin K epoxidase activity" EXACT [EC:1.14.99.20] +synonym: "vitamin K1 epoxidase activity" EXACT [EC:1.14.99.20] +xref: EC:1.14.99.20 +xref: KEGG_REACTION:R03510 +xref: MetaCyc:1.14.99.20-RXN +xref: RHEA:16745 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0047098 +name: Latia-luciferin monooxygenase (demethylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin." [EC:1.14.99.21, MetaCyc:1.14.99.21-RXN] +synonym: "Latia luciferin monooxygenase (demethylating)" EXACT [EC:1.14.99.21] +synonym: "Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)" EXACT [EC:1.14.99.21] +synonym: "luciferase (Latia luciferin)" EXACT [EC:1.14.99.21] +xref: EC:1.14.99.21 +xref: MetaCyc:1.14.99.21-RXN +xref: RHEA:12677 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0047099 +name: CDP-4-dehydro-6-deoxyglucose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose." [EC:1.17.1.1, MetaCyc:1.17.1.1-RXN] +synonym: "CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity" EXACT [EC:1.17.1.1] +synonym: "CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity" EXACT [EC:1.17.1.1] +synonym: "CDP-4-keto-6-deoxyglucose reductase activity" EXACT [EC:1.17.1.1] +synonym: "CDP-4-keto-deoxy-glucose reductase activity" EXACT [EC:1.17.1.1] +synonym: "cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity" EXACT [EC:1.17.1.1] +synonym: "cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity" EXACT [EC:1.17.1.1] +synonym: "NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity" EXACT [EC:1.17.1.1] +xref: EC:1.17.1.1 +xref: MetaCyc:1.17.1.1-RXN +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0047100 +name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate." [EC:1.2.1.13, MetaCyc:1.2.1.13-RXN] +synonym: "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.13] +synonym: "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)" EXACT [EC:1.2.1.13] +synonym: "glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)" EXACT [EC:1.2.1.13] +synonym: "NADP-dependent glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] +synonym: "NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] +synonym: "NADP-triose phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] +synonym: "triosephosphate dehydrogenase (NADP(+)) activity" EXACT [EC:1.2.1.13] +synonym: "triosephosphate dehydrogenase (NADP)" EXACT [EC:1.2.1.13] +synonym: "triosephosphate dehydrogenase (NADP+) activity" EXACT [EC:1.2.1.13] +xref: EC:1.2.1.13 +xref: MetaCyc:1.2.1.13-RXN +xref: RHEA:10296 +is_a: GO:0043891 ! glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity + +[Term] +id: GO:0047101 +name: 2-oxoisovalerate dehydrogenase (acylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA." [EC:1.2.1.25, MetaCyc:1.2.1.25-RXN] +synonym: "2-oxoisovalerate dehydrogenase activity" EXACT [EC:1.2.1.25] +synonym: "3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)" EXACT [EC:1.2.1.25] +xref: EC:1.2.1.25 +xref: MetaCyc:1.2.1.25-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047102 +name: aminomuconate-semialdehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate." [EC:1.2.1.32, MetaCyc:1.2.1.32-RXN] +synonym: "2-aminomuconate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +synonym: "2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity" EXACT [EC:1.2.1.32] +synonym: "2-hydroxymuconate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +synonym: "2-hydroxymuconic acid semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +synonym: "2-hydroxymuconic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +synonym: "alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +synonym: "alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] +xref: EC:1.2.1.32 +xref: MetaCyc:1.2.1.32-RXN +xref: Reactome:R-HSA-71239 "2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+" +xref: RHEA:14469 +xref: UM-BBD_reactionID:r1434 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047103 +name: 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate." [MetaCyc:1.2.1.40-RXN] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity" EXACT [] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity" EXACT [] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity" EXACT [] +synonym: "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity" EXACT [] +synonym: "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity" EXACT [] +synonym: "cholestanetriol-26-al 26-dehydrogenase activity" EXACT [EC:1.2.1.40] +synonym: "THAL-NAD oxidoreductase activity" EXACT [] +synonym: "trihydroxydeoxycoprostanal dehydrogenase activity" EXACT [] +xref: MetaCyc:1.2.1.40-RXN +xref: RHEA:24584 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047104 +name: hexadecanal dehydrogenase (acylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA." [EC:1.2.1.42, RHEA:19705] +synonym: "fatty acyl-CoA reductase activity" BROAD [EC:1.2.1.42] +synonym: "hexadecanal:NAD+ oxidoreductase (CoA-acylating)" EXACT [EC:1.2.1.42] +xref: EC:1.2.1.42 +xref: KEGG_REACTION:R01277 +xref: MetaCyc:1.2.1.42-RXN +xref: RHEA:19705 +xref: UM-BBD_reactionID:r1374 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047105 +name: 4-trimethylammoniobutyraldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate." [EC:1.2.1.47, MetaCyc:1.2.1.47-RXN] +synonym: "4-N-trimethylaminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.47] +synonym: "4-trimethylaminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.47] +synonym: "4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.47] +xref: EC:1.2.1.47 +xref: MetaCyc:1.2.1.47-RXN +xref: RHEA:17985 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047106 +name: 4-hydroxyphenylacetaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate." [EC:1.2.1.53, MetaCyc:1.2.1.53-RXN] +synonym: "4-HPAL dehydrogenase activity" EXACT [EC:1.2.1.53] +synonym: "4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.53] +xref: EC:1.2.1.53 +xref: MetaCyc:1.2.1.53-RXN +xref: RHEA:17273 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0047107 +name: gamma-guanidinobutyraldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH." [EC:1.2.1.54, RHEA:14381] +synonym: "4-guanidinobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.54] +synonym: "4-guanidinobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.54] +synonym: "alpha-guanidinobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.54] +synonym: "GBAL dehydrogenase activity" EXACT [EC:1.2.1.54] +xref: EC:1.2.1.54 +xref: KEGG_REACTION:R03177 +xref: MetaCyc:1.2.1.54-RXN +xref: RHEA:14381 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0047108 +name: (R)-3-hydroxyacid-ester dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH." [EC:1.1.1.279, RHEA:24352] +comment: Note that this term was EC:1.2.1.55. +synonym: "(R)-3-hydroxyacid ester dehydrogenase activity" EXACT [] +synonym: "3-oxo ester (R)-reductase activity" EXACT [EC:1.1.1.279] +synonym: "ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.279] +xref: EC:1.1.1.279 +xref: KEGG_REACTION:R04105 +xref: MetaCyc:1.2.1.55-RXN +xref: RHEA:24352 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047109 +name: (S)-3-hydroxyacid-ester dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH." [EC:1.1.1.280, RHEA:18269] +comment: Note that this term was EC:1.2.1.56. +synonym: "(S)-3-hydroxyacid ester dehydrogenase activity" EXACT [] +synonym: "3-oxo ester (S)-reductase activity" EXACT [EC:1.1.1.280] +synonym: "ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.280] +xref: EC:1.1.1.280 +xref: KEGG_REACTION:R04106 +xref: MetaCyc:1.2.1.56-RXN +xref: RHEA:18269 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047110 +name: phenylglyoxylate dehydrogenase (acylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH." [EC:1.2.1.58, RHEA:10372] +synonym: "phenylglyoxylate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.58] +xref: EC:1.2.1.58 +xref: KEGG_REACTION:R02450 +xref: MetaCyc:1.2.1.58-RXN +xref: RHEA:10372 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047111 +name: formate dehydrogenase (cytochrome-c-553) activity +namespace: molecular_function +def: "Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2." [EC:1.17.2.3, MetaCyc:1.2.2.3-RXN] +synonym: "formate dehydrogenase (cytochrome c-553)" EXACT [EC:1.17.2.3] +synonym: "formate:ferricytochrome-c-553 oxidoreductase activity" EXACT [EC:1.17.2.3] +xref: EC:1.17.2.3 +xref: MetaCyc:1.2.2.3-RXN +xref: RHEA:15189 +is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor + +[Term] +id: GO:0047112 +name: pyruvate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2)." [EC:1.2.3.3, RHEA:20848] +synonym: "phosphate-dependent pyruvate oxidase activity" EXACT [EC:1.2.3.3] +synonym: "pyruvate:oxygen 2-oxidoreductase (phosphorylating)" EXACT [EC:1.2.3.3] +synonym: "pyruvic oxidase activity" EXACT [EC:1.2.3.3] +xref: EC:1.2.3.3 +xref: KEGG_REACTION:R00207 +xref: MetaCyc:1.2.3.3-RXN +xref: RHEA:20848 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0047113 +name: aldehyde dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol." [EC:1.2.5.2, MetaCyc:1.2.99.3-RXN] +synonym: "aldehyde dehydrogenase (acceptor) activity" EXACT [EC:1.2.99.3] +synonym: "aldehyde dehydrogenase (pyrroloquinoline-quinone)" RELATED [] +synonym: "aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity" EXACT [EC:1.2.99.3] +xref: EC:1.2.5.2 +xref: MetaCyc:1.2.99.3-RXN +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0047114 +name: kynurenate-7,8-dihydrodiol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH." [EC:1.3.1.18, RHEA:22248] +synonym: "7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity" EXACT [EC:1.3.1.18] +synonym: "7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.18] +synonym: "7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity" EXACT [EC:1.3.1.18] +xref: EC:1.3.1.18 +xref: KEGG_REACTION:R03251 +xref: MetaCyc:1.3.1.18-RXN +xref: RHEA:22248 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047115 +name: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol." [EC:1.3.1.20, MetaCyc:1.3.1.20-RXN] +synonym: "dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.20] +synonym: "trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.20] +xref: EC:1.3.1.20 +xref: MetaCyc:1.3.1.20-RXN +xref: RHEA:16729 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047116 +name: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol." [EC:1.3.1.25, MetaCyc:1.3.1.25-RXN] +synonym: "(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.25] +synonym: "2-hydro-1,2-dihydroxybenzoate dehydrogenase activity" EXACT [EC:1.3.1.25] +synonym: "3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity" EXACT [EC:1.3.1.25] +synonym: "3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity" EXACT [EC:1.3.1.25] +synonym: "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity" EXACT [EC:1.3.1.25] +synonym: "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.25] +synonym: "DHB dehydrogenase activity" EXACT [EC:1.3.1.25] +synonym: "DHBDH activity" EXACT [EC:1.3.1.25] +synonym: "dihydrodihydroxybenzoate dehydrogenase activity" EXACT [EC:1.3.1.25] +xref: EC:1.3.1.25 +xref: MetaCyc:1.3.1.25-RXN +xref: RHEA:11560 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047117 +name: enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+." [EC:1.3.1.39, MetaCyc:1.3.1.39-RXN] +synonym: "acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)" EXACT [EC:1.3.1.39] +synonym: "enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity" EXACT [] +synonym: "enoyl-ACP reductase (NADPH, A-specific) activity" EXACT [] +synonym: "enoyl-ACp reductase activity" EXACT [EC:1.3.1.39] +synonym: "enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.39] +synonym: "enoyl-acyl-carrier-protein reductase (NADPH, A-specific)" EXACT [EC:1.3.1.39] +xref: EC:1.3.1.39 +xref: MetaCyc:1.3.1.39-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047118 +name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH." [EC:1.3.1.40, RHEA:24268] +synonym: "2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.40] +synonym: "2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.40] +xref: EC:1.3.1.40 +xref: KEGG_REACTION:R03463 +xref: MetaCyc:1.3.1.40-RXN +xref: RHEA:24268 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047119 +name: 2-methyl-branched-chain-enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH." [EC:1.3.1.52, RHEA:24532] +synonym: "2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity" EXACT [EC:1.3.1.52] +xref: EC:1.3.1.52 +xref: KEGG_REACTION:R03169 +xref: MetaCyc:1.3.1.52-RXN +xref: RHEA:24532 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047120 +name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity +namespace: molecular_function +alt_id: GO:0018514 +def: "Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH." [EC:1.3.1.53, RHEA:10744] +synonym: "(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity" EXACT [EC:1.3.1.53] +synonym: "(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.53] +synonym: "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.53] +synonym: "dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity" EXACT [EC:1.3.1.53] +synonym: "terephthalate 1,2-cis-dihydrodiol dehydrogenase activity" EXACT [] +xref: EC:1.3.1.53 +xref: KEGG_REACTION:R01633 +xref: MetaCyc:1.3.1.53-RXN +xref: RHEA:10744 +xref: UM-BBD_reactionID:r0151 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047121 +name: isoquinoline 1-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one." [EC:1.3.99.16, RHEA:11588] +synonym: "isoquinoline:acceptor 1-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.16] +xref: EC:1.3.99.16 +xref: KEGG_REACTION:R05151 +xref: MetaCyc:1.3.99.16-RXN +xref: RHEA:11588 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047122 +name: quinaldate 4-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate." [EC:1.3.99.18, RHEA:16697] +synonym: "quinaldic acid 4-oxidoreductase activity" EXACT [EC:1.3.99.18] +synonym: "quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.18] +xref: EC:1.3.99.18 +xref: KEGG_REACTION:R03687 +xref: MetaCyc:1.3.99.18-RXN +xref: RHEA:16697 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047123 +name: quinoline-4-carboxylate 2-oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2)." [EC:1.3.99.19, RHEA:14949] +synonym: "quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.19] +synonym: "quinoline-4-carboxylic acid 2-oxidoreductase activity" EXACT [EC:1.3.99.19] +xref: EC:1.3.99.19 +xref: KEGG_REACTION:R05183 +xref: MetaCyc:1.3.99.19-RXN +xref: RHEA:14949 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047124 +name: L-erythro-3,5-diaminohexanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+)." [EC:1.4.1.11, RHEA:19633] +synonym: "L-3,5-diaminohexanoate dehydrogenase activity" EXACT [EC:1.4.1.11] +synonym: "L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.11] +xref: EC:1.4.1.11 +xref: KEGG_REACTION:R03349 +xref: MetaCyc:1.4.1.11-RXN +xref: RHEA:19633 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047125 +name: delta1-piperideine-2-carboxylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate." [EC:1.5.1.21] +synonym: "1,2-didehydropipecolate reductase activity" EXACT [EC:1.5.1.21] +synonym: "1,2-didehydropipecolic reductase activity" EXACT [EC:1.5.1.21] +synonym: "D1-piperideine-2-carboxylate reductase activity" EXACT [] +synonym: "delta 1-piperideine-2-carboxylate reductase activity" EXACT [] +synonym: "L-pipecolate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.5.1.21] +synonym: "P2C reductase activity" EXACT [EC:1.5.1.21] +xref: EC:1.5.1.21 +xref: MetaCyc:RXN-8166 +xref: RHEA:12524 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047126 +name: N5-(carboxyethyl)ornithine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate." [EC:1.5.1.24, RHEA:18661] +synonym: "5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)" EXACT [EC:1.5.1.24] +synonym: "N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)" EXACT [EC:1.5.1.24] +xref: EC:1.5.1.24 +xref: KEGG_REACTION:R00666 +xref: MetaCyc:1.5.1.24-RXN +xref: RHEA:18661 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047127 +name: thiomorpholine-carboxylate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate." [EC:1.5.1.25, MetaCyc:1.5.1.25-RXN] +synonym: "ketimine reductase activity" EXACT [EC:1.5.1.25] +synonym: "ketimine-reducing enzyme" RELATED [EC:1.5.1.25] +synonym: "thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity" EXACT [EC:1.5.1.25] +xref: EC:1.5.1.25 +xref: MetaCyc:1.5.1.25-RXN +xref: Reactome:R-HSA-5693347 "CRYM reduces P2C to PPCA" +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047128 +name: 1,2-dehydroreticulinium reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH." [EC:1.5.1.27, RHEA:17569] +synonym: "(R)-reticuline:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.27] +synonym: "1,2-dehydroreticulinium ion reductase activity" EXACT [EC:1.5.1.27] +xref: EC:1.5.1.27 +xref: KEGG_REACTION:R04695 +xref: MetaCyc:1.5.1.27-RXN +xref: RHEA:17569 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047129 +name: opine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate." [EC:1.5.1.28, RHEA:21592] +synonym: "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)" EXACT [EC:1.5.1.28] +synonym: "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming)" EXACT [EC:1.5.1.28] +xref: EC:1.5.1.28 +xref: KEGG_REACTION:R03732 +xref: MetaCyc:1.5.1.28-RXN +xref: RHEA:21592 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047130 +name: saccharopine dehydrogenase (NADP+, L-lysine-forming) activity +namespace: molecular_function +alt_id: GO:0010010 +def: "Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH." [EC:1.5.1.8, RHEA:19373] +synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.8] +synonym: "L-lysine-alpha-ketoglutarate reductase activity" EXACT [EC:1.5.1.8] +synonym: "lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)" EXACT [EC:1.5.1.8] +synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.8] +synonym: "saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity" EXACT [EC:1.5.1.8] +xref: EC:1.5.1.8 +xref: KEGG_REACTION:R00716 +xref: MetaCyc:1.5.1.8-RXN +xref: Reactome:R-HSA-70938 "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O" +xref: RHEA:19373 +is_a: GO:0004753 ! saccharopine dehydrogenase activity + +[Term] +id: GO:0047131 +name: saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH." [EC:1.5.1.9, RHEA:24520] +synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.9] +synonym: "aminoadipic semialdehyde synthase activity" EXACT [EC:1.5.1.9] +synonym: "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)" EXACT [EC:1.5.1.9] +synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.9] +synonym: "NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)" EXACT [EC:1.5.1.9] +synonym: "saccharopin dehydrogenase activity" EXACT [EC:1.5.1.9] +xref: EC:1.5.1.9 +xref: KEGG_REACTION:R02313 +xref: MetaCyc:1.5.1.9-RXN +xref: Reactome:R-HSA-70940 "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+" +xref: RHEA:24520 +is_a: GO:0004753 ! saccharopine dehydrogenase activity + +[Term] +id: GO:0047132 +name: dihydrobenzophenanthridine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine." [EC:1.5.3.12, MetaCyc:1.5.3.12-RXN] +synonym: "dihydrobenzophenanthridine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.12] +xref: EC:1.5.3.12 +xref: MetaCyc:1.5.3.12-RXN +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0047133 +name: dimethylamine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine." [EC:1.5.8.1, MetaCyc:1.5.8.1-RXN] +synonym: "dimethylamine:electron-transferring flavoprotein oxidoreductase activity" EXACT [EC:1.5.8.1] +synonym: "DMADh activity" RELATED [EC:1.5.8.1] +xref: EC:1.5.8.1 +xref: MetaCyc:1.5.8.1-RXN +xref: UM-BBD_reactionID:r1380 +is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor + +[Term] +id: GO:0047134 +name: protein-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+." [EC:1.8.1.8, MetaCyc:1.6.4.4-RXN] +synonym: "disulfide reductase activity" EXACT [EC:1.8.1.8] +synonym: "insulin-glutathione transhydrogenase activity" EXACT [EC:1.8.1.8] +synonym: "NAD(P)H2:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.1.8] +synonym: "NAD(P)H:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.1.8] +synonym: "protein disulfide reductase activity" EXACT [EC:1.8.1.8] +synonym: "protein disulphide reductase activity" EXACT [EC:1.8.1.8] +synonym: "protein-disulfide reductase (NAD(P)H) activity" EXACT [] +synonym: "protein-disulphide reductase activity" EXACT [] +synonym: "protein-dithiol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.8] +xref: EC:1.8.1.8 +xref: MetaCyc:1.6.4.4-RXN +is_a: GO:0015036 ! disulfide oxidoreductase activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0047135 +name: bis-gamma-glutamylcystine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH." [EC:1.8.1.13, RHEA:11980] +synonym: "bis-g-glutamylcystine reductase (NADPH) activity" EXACT [] +synonym: "Bis-gamma-glutamylcystine reductase (NADPH)" EXACT [EC:1.8.1.13] +synonym: "bis-gamma-glutamylcystine reductase (NADPH) activity" EXACT [EC:1.8.1.13] +synonym: "gamma-glutamylcysteine:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.13] +synonym: "NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity" EXACT [EC:1.8.1.13] +synonym: "NADPH:bis-gamma-glutamylcysteine oxidoreductase activity" EXACT [EC:1.8.1.13] +xref: EC:1.8.1.13 +xref: KEGG_REACTION:R02742 +xref: MetaCyc:1.6.4.9-RXN +xref: RHEA:11980 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0047136 +name: 4-(dimethylamino)phenylazoxybenzene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH." [EC:1.7.1.11, RHEA:19789] +synonym: "4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.11] +synonym: "dimethylaminoazobenzene N-oxide reductase activity" EXACT [EC:1.7.1.11] +synonym: "N,N-dimethyl-p-aminoazobenzene oxide reductase activity" EXACT [EC:1.7.1.11] +synonym: "NADPH-dependent DMAB N-oxide reductase activity" EXACT [EC:1.7.1.11] +synonym: "NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity" EXACT [EC:1.7.1.11] +synonym: "NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity" EXACT [EC:1.7.1.11] +xref: EC:1.7.1.11 +xref: KEGG_REACTION:R04303 +xref: MetaCyc:1.6.6.12-RXN +xref: RHEA:19789 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0047137 +name: N-hydroxy-2-acetamidofluorene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+." [EC:1.7.1.12, MetaCyc:1.7.1.12-RXN] +synonym: "2-acetamidofluorene:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.12] +synonym: "N-hydroxy-2-acetylaminofluorene reductase activity" EXACT [EC:1.7.1.12] +synonym: "NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity" EXACT [EC:1.7.1.12] +synonym: "NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity" EXACT [EC:1.7.1.12] +xref: EC:1.7.1.12 +xref: MetaCyc:1.7.1.12-RXN +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0047138 +name: aquacobalamin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+." [EC:1.16.1.3, MetaCyc:1.6.99.12-RXN] +synonym: "aquocobalamin reductase activity" EXACT [EC:1.16.1.3] +synonym: "B(12a) reductase activity" EXACT [EC:1.16.1.3] +synonym: "B12a reductase activity" EXACT [EC:1.16.1.3] +synonym: "cob(II)alamin:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.3] +synonym: "NADH-linked aquacobalamin reductase activity" EXACT [EC:1.16.1.3] +synonym: "NADH2:cob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.3] +synonym: "NADH:cob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.3] +synonym: "vitamin B(12a) reductase activity" EXACT [EC:1.16.1.3] +synonym: "vitamin B12a reductase activity" EXACT [EC:1.16.1.3] +xref: EC:1.16.1.3 +xref: MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN +xref: RHEA:24472 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0047139 +name: glutathione-homocystine transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine." [EC:1.8.4.1, MetaCyc:1.8.4.1-RXN] +synonym: "glutathione:homocystine oxidoreductase activity" EXACT [EC:1.8.4.1] +xref: EC:1.8.4.1 +xref: MetaCyc:1.8.4.1-RXN +xref: RHEA:11464 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0047140 +name: glutathione-CoA-glutathione transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione." [EC:1.8.4.3, MetaCyc:1.8.4.3-RXN] +synonym: "CoA:glutathione-disulfide oxidoreductase activity" EXACT [EC:1.8.4.3] +synonym: "coenzyme A:glutathione-disulfide oxidoreductase activity" EXACT [EC:1.8.4.3] +synonym: "coenzyme A:oxidized-glutathione oxidoreductase activity" EXACT [EC:1.8.4.3] +synonym: "glutathione coenzyme A-glutathione transhydrogenase activity" EXACT [EC:1.8.4.3] +synonym: "glutathione-coenzyme A glutathione disulfide transhydrogenase activity" EXACT [EC:1.8.4.3] +synonym: "glutathione:coenzyme A-glutathione transhydrogenase activity" EXACT [EC:1.8.4.3] +xref: EC:1.8.4.3 +xref: MetaCyc:1.8.4.3-RXN +xref: RHEA:13125 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0047141 +name: glutathione-cystine transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine." [EC:1.8.4.4, MetaCyc:1.8.4.4-RXN] +synonym: "glutathione:cystine oxidoreductase" EXACT [EC:1.8.4.4] +synonym: "GSH-cystine transhydrogenase" EXACT [EC:1.8.4.4] +synonym: "NADPH-dependent GSH-cystine transhydrogenase" EXACT [EC:1.8.4.4] +xref: EC:1.8.4.4 +xref: MetaCyc:1.8.4.4-RXN +xref: RHEA:12613 +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0047142 +name: enzyme-thiol transhydrogenase (glutathione-disulfide) activity +namespace: molecular_function +def: "Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase." [EC:1.8.4.7, MetaCyc:1.8.4.7-RXN] +synonym: "[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity" EXACT [EC:1.8.4.7] +synonym: "enzyme-thiol transhydrogenase (glutathione-disulphide) activity" EXACT [] +synonym: "enzyme-thiol transhydrogenase (oxidized-glutathione) activity" EXACT [] +synonym: "glutathione-dependent thiol:disulfide oxidoreductase activity" EXACT [EC:1.8.4.7] +synonym: "thiol:disulfide oxidoreductase activity" EXACT [EC:1.8.4.7] +synonym: "thiol:disulphide oxidoreductase activity" EXACT [EC:1.8.4.7] +synonym: "xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity" EXACT [EC:1.8.4.7] +synonym: "xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity" EXACT [EC:1.8.4.7] +xref: EC:1.8.4.7 +xref: MetaCyc:1.8.4.7-RXN +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0047143 +name: chlorate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+)." [EC:1.97.1.1, RHEA:16349] +synonym: "chlorate reductase C" RELATED [EC:1.97.1.1] +synonym: "chlorite:acceptor oxidoreductase activity" EXACT [EC:1.97.1.1] +xref: EC:1.97.1.1 +xref: KEGG_REACTION:R03575 +xref: MetaCyc:1.97.1.1-RXN +xref: RHEA:16349 +xref: UM-BBD_reactionID:r0981 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0047144 +name: 2-acylglycerol-3-phosphate O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA." [EC:2.3.1.52, GOC:ab, MetaCyc:2-ACYL2.3.1.15-RXN, RHEA:14233] +synonym: "2-acylglycerophosphate acyltransferase activity" EXACT [EC:2.3.1.52] +synonym: "acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity" EXACT [EC:2.3.1.52] +xref: EC:2.3.1.52 +xref: MetaCyc:2-ACYL2.3.1.15-RXN +xref: Reactome:R-HSA-1482533 "2-acyl LPC is acylated to PC by LPCAT" +xref: Reactome:R-HSA-1482546 "2-acyl LPG is acylated to PG by CRLS1 (IM)" +xref: Reactome:R-HSA-1482626 "2-acyl LPI is acylated to PI by MBOAT7" +xref: Reactome:R-HSA-1482635 "2-acyl LPG is acylated to PG by LPGAT" +xref: Reactome:R-HSA-1482646 "2-acyl LPE is acylated to PE by LPEAT" +xref: Reactome:R-HSA-1482691 "2-acyl LPS is acylated to PS by LPSAT" +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0042171 ! lysophosphatidic acid acyltransferase activity + +[Term] +id: GO:0047145 +name: demethylsterigmatocystin 6-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine." [EC:2.1.1.109, MetaCyc:2.1.1.109-RXN] +synonym: "demethylsterigmatocystin methyltransferase activity" EXACT [EC:2.1.1.109] +synonym: "O-methyltransferase I" RELATED [EC:2.1.1.109] +synonym: "S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity" EXACT [EC:2.1.1.109] +xref: EC:2.1.1.109 +xref: MetaCyc:2.1.1.109-RXN +xref: RHEA:11504 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0047146 +name: sterigmatocystin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine." [EC:2.1.1.110, MetaCyc:2.1.1.110-RXN] +synonym: "O-methyltransferase II activity" RELATED [EC:2.1.1.110] +synonym: "S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity" EXACT [EC:2.1.1.110] +synonym: "S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity" EXACT [EC:2.1.1.110] +synonym: "sterigmatocystin 8-O-methyltransferase activity" EXACT [EC:2.1.1.110] +synonym: "sterigmatocystin methyltransferase activity" EXACT [EC:2.1.1.110] +xref: EC:2.1.1.110 +xref: MetaCyc:2.1.1.110-RXN +xref: RHEA:15561 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0047147 +name: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+)." [EC:2.1.1.19, RHEA:13693] +synonym: "trimethylsulfonium-tetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.19] +synonym: "trimethylsulfonium:tetrahydrofolate N-methyltransferase activity" EXACT [EC:2.1.1.19] +synonym: "trimethylsulphonium-tetrahydrofolate N-methyltransferase activity" EXACT [] +xref: EC:2.1.1.19 +xref: KEGG_REACTION:R02573 +xref: MetaCyc:2.1.1.19-RXN +xref: RHEA:13693 +is_a: GO:0008170 ! N-methyltransferase activity + +[Term] +id: GO:0047148 +name: methylamine-glutamate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+)." [EC:2.1.1.21, RHEA:15837] +synonym: "methylamine-glutamate methyltransferase activity" EXACT [EC:2.1.1.21] +synonym: "methylamine:L-glutamate N-methyltransferase activity" EXACT [EC:2.1.1.21] +synonym: "N-methylglutamate synthase activity" EXACT [EC:2.1.1.21] +xref: EC:2.1.1.21 +xref: KEGG_REACTION:R01586 +xref: MetaCyc:2.1.1.21-RXN +xref: RHEA:15837 +is_a: GO:0008170 ! N-methyltransferase activity + +[Term] +id: GO:0047149 +name: thetin-homocysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+)." [EC:2.1.1.3, RHEA:22788] +synonym: "dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.3] +synonym: "dimethylthetin-homocysteine methyltransferase activity" EXACT [EC:2.1.1.3] +synonym: "thetin-homocysteine methylpherase activity" EXACT [EC:2.1.1.3] +xref: EC:2.1.1.3 +xref: KEGG_REACTION:R04153 +xref: MetaCyc:2.1.1.3-RXN +xref: RHEA:22788 +is_a: GO:0008172 ! S-methyltransferase activity + +[Term] +id: GO:0047150 +name: betaine-homocysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine." [EC:2.1.1.5, RHEA:22336] +synonym: "betaine-homocysteine methyltransferase activity" EXACT [EC:2.1.1.5] +synonym: "betaine-homocysteine transmethylase activity" EXACT [EC:2.1.1.5] +synonym: "trimethylammonioacetate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.5] +xref: EC:2.1.1.5 +xref: KEGG_REACTION:R02821 +xref: MetaCyc:2.1.1.5-RXN +xref: Reactome:R-HSA-1614654 "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY" +xref: RHEA:22336 +is_a: GO:0008172 ! S-methyltransferase activity + +[Term] +id: GO:0047151 +name: methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+." [EC:2.1.1.74, MetaCyc:2.1.1.74-RXN] +synonym: "5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity" EXACT [EC:2.1.1.74] +synonym: "5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity" EXACT [EC:2.1.1.74] +synonym: "folate-dependent ribothymidyl synthase activity" EXACT [EC:2.1.1.74] +synonym: "methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity" EXACT [EC:2.1.1.74] +synonym: "methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity" EXACT [] +xref: EC:2.1.1.74 +xref: KEGG_REACTION:R03704 +xref: MetaCyc:2.1.1.74-RXN +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0047152 +name: methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity +namespace: molecular_function +alt_id: GO:1990087 +def: "Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide." [EC:2.1.1.90, MetaCyc:2.1.1.90-RXN] +comment: This function is the first step in the pathway of methanogenesis from methanol. +synonym: "methanol cobalamin methyltransferase activity" EXACT [EC:2.1.1.90] +synonym: "methanol-corrinoid protein Co-methyltransferase" EXACT [] +synonym: "methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity" EXACT [EC:2.1.1.90] +synonym: "methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity" EXACT [EC:2.1.1.90] +synonym: "methanol:corrinoid methyltransferase activity" EXACT [] +synonym: "methyltransferase 1" BROAD [] +synonym: "MT 1" RELATED [EC:2.1.1.90] +synonym: "MT1" RELATED [] +synonym: "MtaB" RELATED [] +xref: EC:2.1.1.90 +xref: MetaCyc:2.1.1.90-RXN +xref: RHEA:21344 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0047153 +name: deoxycytidylate 5-hydroxymethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate." [EC:2.1.2.8, RHEA:11280] +synonym: "5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity" EXACT [EC:2.1.2.8] +synonym: "d-cytidine 5'-monophosphate hydroxymethylase activity" EXACT [EC:2.1.2.8] +synonym: "dCMP hydroxymethylase activity" EXACT [EC:2.1.2.8] +synonym: "deoxyCMP hydroxymethylase activity" EXACT [EC:2.1.2.8] +synonym: "deoxycytidylate hydroxymethylase activity" EXACT [EC:2.1.2.8] +synonym: "deoxycytidylate hydroxymethyltransferase activity" EXACT [] +synonym: "deoxycytidylic hydroxymethylase activity" EXACT [EC:2.1.2.8] +xref: EC:2.1.2.8 +xref: KEGG_REACTION:R01669 +xref: MetaCyc:2.1.2.8-RXN +xref: RHEA:11280 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0047154 +name: methylmalonyl-CoA carboxytransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA." [EC:2.1.3.1, MetaCyc:2.1.3.1-RXN] +synonym: "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate" RELATED [EC:2.1.3.1] +synonym: "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity" EXACT [EC:2.1.3.1] +synonym: "(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity" EXACT [EC:2.1.3.1] +synonym: "(S)-methylmalonyl-CoA:pyruvate carboxytransferase activity" EXACT [EC:2.1.3.1] +synonym: "methylmalonyl coenzyme A carboxyltransferase activity" EXACT [EC:2.1.3.1] +synonym: "methylmalonyl-CoA carboxyltransferase activity" EXACT [] +synonym: "methylmalonyl-CoA transcarboxylase activity" EXACT [EC:2.1.3.1] +synonym: "oxalacetic transcarboxylase activity" EXACT [EC:2.1.3.1] +synonym: "transcarboxylase activity" RELATED [EC:2.1.3.1] +xref: EC:2.1.3.1 +xref: MetaCyc:2.1.3.1-RXN +xref: RHEA:20764 +xref: UM-BBD_reactionID:r0923 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0047155 +name: 3-hydroxymethylcephem carbamoyltransferase activity +namespace: molecular_function +alt_id: GO:0045447 +def: "Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem." [EC:2.1.3.7, MetaCyc:2.1.3.7-RXN] +synonym: "3'-hydroxymethylcephem-O-carbamoyltransferase activity" EXACT [] +synonym: "carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity" EXACT [EC:2.1.3.7] +xref: EC:2.1.3.7 +xref: MetaCyc:2.1.3.7-RXN +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0047156 +name: acetoin-ribose-5-phosphate transaldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde." [EC:2.2.1.4, RHEA:21504] +synonym: "1-deoxy-D-altro-heptulose-7-phosphate synthase activity" EXACT [EC:2.2.1.4] +synonym: "1-deoxy-D-altro-heptulose-7-phosphate synthetase activity" EXACT [EC:2.2.1.4] +synonym: "3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity" EXACT [EC:2.2.1.4] +synonym: "3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity" EXACT [EC:2.2.1.4] +xref: EC:2.2.1.4 +xref: KEGG_REACTION:R02345 +xref: MetaCyc:2.2.1.4-RXN +xref: RHEA:21504 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0047157 +name: myelin-proteolipid O-palmitoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA." [EC:2.3.1.100, MetaCyc:2.3.1.100-RXN] +synonym: "[myelin-proteolipid] O-palmitoyltransferase activity" EXACT [EC:2.3.1.100] +synonym: "acyl-protein synthase activity" BROAD [EC:2.3.1.100] +synonym: "myelin PLP acyltransferase activity" EXACT [EC:2.3.1.100] +synonym: "palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity" EXACT [EC:2.3.1.100] +xref: EC:2.3.1.100 +xref: MetaCyc:2.3.1.100-RXN +is_a: GO:0016416 ! O-palmitoyltransferase activity + +[Term] +id: GO:0047158 +name: sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose." [EC:2.3.1.103, RHEA:22664] +synonym: "1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.103] +synonym: "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity" EXACT [EC:2.3.1.103] +synonym: "hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.103] +xref: EC:2.3.1.103 +xref: KEGG_REACTION:R00063 +xref: MetaCyc:2.3.1.103-RXN +xref: RHEA:22664 +is_a: GO:0016753 ! O-sinapoyltransferase activity + +[Term] +id: GO:0047159 +name: 1-alkenylglycerophosphocholine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA." [EC:2.3.1.104, MetaCyc:2.3.1.104-RXN] +synonym: "acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.25] +xref: EC:2.3.1.25 +xref: MetaCyc:2.3.1.104-RXN +xref: RHEA:10344 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047160 +name: alkylglycerophosphate 2-O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA." [EC:2.3.1.105, RHEA:18557] +synonym: "acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity" EXACT [EC:2.3.1.105] +synonym: "alkyllyso-GP:acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.105] +xref: EC:2.3.1.105 +xref: KEGG_REACTION:R03455 +xref: MetaCyc:2.3.1.105-RXN +xref: RHEA:18557 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047161 +name: tartronate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate." [EC:2.3.1.106, RHEA:10952] +synonym: "hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.106] +synonym: "sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.106] +synonym: "tartronate sinapoyltransferase activity" EXACT [EC:2.3.1.106] +xref: EC:2.3.1.106 +xref: KEGG_REACTION:R03965 +xref: MetaCyc:2.3.1.106-RXN +xref: RHEA:10952 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047162 +name: 17-O-deacetylvindoline O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA." [EC:2.3.1.107, RHEA:24496] +synonym: "17-O-deacetylvindoline-17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "DAT activity" EXACT [EC:2.3.1.107] +synonym: "deacetylvindoline acetyltransferase activity" EXACT [EC:2.3.1.107] +synonym: "deacetylvindoline O-acetyltransferase activity" EXACT [EC:2.3.1.107] +xref: EC:2.3.1.107 +xref: KEGG_REACTION:R03230 +xref: MetaCyc:2.3.1.107-RXN +xref: RHEA:24496 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047163 +name: 3,4-dichloroaniline N-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA." [EC:2.3.1.114, RHEA:21060] +synonym: "malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity" EXACT [EC:2.3.1.114] +xref: EC:2.3.1.114 +xref: KEGG_REACTION:R04050 +xref: MetaCyc:2.3.1.114-RXN +xref: RHEA:21060 +is_a: GO:0050735 ! N-malonyltransferase activity + +[Term] +id: GO:0047164 +name: isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA." [EC:2.3.1.115, MetaCyc:2.3.1.115-RXN] +synonym: "flavone (flavonol) 7-O-glycoside malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity" EXACT [EC:2.3.1.115] +synonym: "MAT-7" RELATED [EC:2.3.1.115] +xref: EC:2.3.1.115 +xref: MetaCyc:2.3.1.115-RXN +xref: RHEA:15581 +is_a: GO:0050736 ! O-malonyltransferase activity + +[Term] +id: GO:0047165 +name: flavonol-3-O-beta-glucoside O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA." [EC:2.3.1.116, MetaCyc:2.3.1.116-RXN] +synonym: "flavonol 3-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.116] +synonym: "malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.116] +synonym: "malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.116] +synonym: "MAT-3" RELATED [EC:2.3.1.116] +xref: EC:2.3.1.116 +xref: MetaCyc:2.3.1.116-RXN +xref: RHEA:20085 +is_a: GO:0050736 ! O-malonyltransferase activity + +[Term] +id: GO:0047166 +name: 1-alkenylglycerophosphoethanolamine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA." [EC:2.3.1.121, MetaCyc:2.3.1.121-RXN] +synonym: "acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity" EXACT [EC:2.3.1.121] +xref: EC:2.3.1.121 +xref: MetaCyc:2.3.1.121-RXN +xref: RHEA:16245 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047167 +name: 1-alkyl-2-acetylglycerol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA." [EC:2.3.1.125, MetaCyc:2.3.1.125-RXN] +synonym: "1-hexadecyl-2-acetylglycerol acyltransferase activity" EXACT [EC:2.3.1.125] +synonym: "acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity" EXACT [EC:2.3.1.125] +xref: EC:2.3.1.125 +xref: MetaCyc:2.3.1.125-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047168 +name: isocitrate O-dihydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA." [EC:2.3.1.126, RHEA:20756] +synonym: "caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.126] +xref: EC:2.3.1.126 +xref: KEGG_REACTION:R01946 +xref: MetaCyc:2.3.1.126-RXN +xref: RHEA:20756 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047169 +name: galactarate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA." [EC:2.3.1.130, RHEA:12997] +synonym: "feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.130] +synonym: "galacturate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.130] +xref: EC:2.3.1.130 +xref: KEGG_REACTION:R03727 +xref: MetaCyc:2.3.1.130-RXN +xref: RHEA:12997 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047170 +name: glucarate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA." [EC:2.3.1.131, RHEA:23308] +synonym: "sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.131] +xref: EC:2.3.1.131 +xref: KEGG_REACTION:R02899 +xref: MetaCyc:2.3.1.131-RXN +xref: RHEA:23308 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047171 +name: glucarolactone O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA." [EC:2.3.1.132, MetaCyc:2.3.1.132-RXN] +synonym: "sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.132] +xref: EC:2.3.1.132 +xref: MetaCyc:2.3.1.132-RXN +xref: RHEA:14261 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047172 +name: shikimate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA." [EC:2.3.1.133, MetaCyc:2.3.1.133-RXN] +synonym: "4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.133] +synonym: "shikimate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.133] +xref: EC:2.3.1.133 +xref: MetaCyc:2.3.1.133-RXN +xref: RHEA:12124 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047173 +name: phosphatidylcholine-retinol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine." [EC:2.3.1.135, MetaCyc:2.3.1.135-RXN] +synonym: "lecithin--retinol acyltransferase activity" EXACT [EC:2.3.1.135] +synonym: "phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity" EXACT [EC:2.3.1.135] +synonym: "phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity" EXACT [EC:2.3.1.135] +xref: EC:2.3.1.135 +xref: MetaCyc:2.3.1.135-RXN +xref: Reactome:R-HSA-975608 "LRAT esterifies RBP2:atROL and FACYLs to atREs" +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047174 +name: putrescine N-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+)." [EC:2.3.1.138, RHEA:12436] +synonym: "caffeoyl-CoA putrescine N-caffeoyl transferase activity" EXACT [EC:2.3.1.138] +synonym: "caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.138] +synonym: "hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.138] +synonym: "PHT" RELATED [EC:2.3.1.138] +synonym: "putrescine hydroxycinnamoyl transferase activity" EXACT [EC:2.3.1.138] +synonym: "putrescine hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.138] +xref: EC:2.3.1.138 +xref: KEGG_REACTION:R01944 +xref: MetaCyc:2.3.1.138-RXN +xref: RHEA:12436 +is_a: GO:0016410 ! N-acyltransferase activity +is_a: GO:0050734 ! hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047175 +name: galactosylacylglycerol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein]." [EC:2.3.1.141, MetaCyc:2.3.1.141-RXN] +synonym: "acyl-ACP:lyso-MGDG acyltransferase activity" EXACT [EC:2.3.1.141] +synonym: "acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity" EXACT [EC:2.3.1.141] +synonym: "acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.141] +xref: EC:2.3.1.141 +xref: MetaCyc:2.3.1.141-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047176 +name: beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose." [EC:2.3.1.143, RHEA:19109] +synonym: "1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] +synonym: "beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity" EXACT [EC:2.3.1.143] +synonym: "beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] +synonym: "beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] +xref: EC:2.3.1.143 +xref: KEGG_REACTION:R04498 +xref: MetaCyc:2.3.1.143-RXN +xref: RHEA:19109 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047177 +name: glycerophospholipid arachidonoyl-transferase (CoA-independent) activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine." [EC:2.3.1.147, MetaCyc:2.3.1.147-RXN] +synonym: "1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)" EXACT [EC:2.3.1.147] +synonym: "1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)" EXACT [EC:2.3.1.147] +xref: EC:2.3.1.147 +xref: MetaCyc:2.3.1.147-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047178 +name: glycerophospholipid acyltransferase (CoA-dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine." [EC:2.3.1.148, MetaCyc:2.3.1.148-RXN] +synonym: "1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent)" EXACT [EC:2.3.1.148] +xref: EC:2.3.1.148 +xref: MetaCyc:2.3.1.148-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047179 +name: platelet-activating factor acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid." [EC:2.3.1.149, MetaCyc:2.3.1.149-RXN] +synonym: "1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity" EXACT [EC:2.3.1.149] +synonym: "PAF acetyltransferase activity" EXACT [] +xref: EC:2.3.1.149 +xref: MetaCyc:2.3.1.149-RXN +is_a: GO:0016407 ! acetyltransferase activity + +[Term] +id: GO:0047180 +name: salutaridinol 7-O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA." [EC:2.3.1.150, RHEA:22856] +synonym: "acetyl-CoA:salutaridinol 7-O-acetyltransferase activity" EXACT [EC:2.3.1.150] +xref: EC:2.3.1.150 +xref: KEGG_REACTION:R04723 +xref: MetaCyc:2.3.1.150-RXN +xref: RHEA:22856 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047181 +name: tetrahydroxybenzophenone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A." [EC:2.3.1.151, MetaCyc:2.3.1.151-RXN] +synonym: "malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity" EXACT [EC:2.3.1.151] +xref: EC:2.3.1.151 +xref: MetaCyc:2.3.1.151-RXN +xref: RHEA:19305 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047182 +name: alcohol O-cinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate." [EC:2.3.1.152, MetaCyc:2.3.1.152-RXN] +synonym: "1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity" EXACT [EC:2.3.1.152] +xref: EC:2.3.1.152 +xref: MetaCyc:2.3.1.152-RXN +xref: RHEA:23524 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047183 +name: anthocyanin 5-aromatic acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA." [EC:2.3.1.153, MetaCyc:2.3.1.153-RXN] +synonym: "hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.153] +xref: EC:2.3.1.153 +xref: MetaCyc:RXN-7945 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047184 +name: 1-acylglycerophosphocholine O-acyltransferase activity +namespace: molecular_function +alt_id: GO:0000507 +def: "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA." [EC:2.3.1.23, MetaCyc:2.3.1.23-RXN] +synonym: "1-acyl-sn-glycero-3-phosphocholine acyltransferase activity" EXACT [EC:2.3.1.23] +synonym: "acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity" EXACT [EC:2.3.1.23] +synonym: "acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity" EXACT [EC:2.3.1.23] +synonym: "acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.23] +synonym: "lysolecithin acyltransferase activity" EXACT [EC:2.3.1.23] +synonym: "lysophosphatide acyltransferase activity" EXACT [EC:2.3.1.23] +synonym: "lysophosphatidylcholine acyltransferase activity" EXACT [EC:2.3.1.23] +xref: EC:2.3.1.23 +xref: MetaCyc:2.3.1.23-RXN +xref: Reactome:R-HSA-1482794 "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)" +xref: RHEA:12937 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047185 +name: N-acetylneuraminate 4-O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA." [EC:2.3.1.44, RHEA:18305] +synonym: "acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity" EXACT [EC:2.3.1.44] +synonym: "sialate O-acetyltransferase" BROAD [EC:2.3.1.44] +xref: EC:2.3.1.44 +xref: KEGG_REACTION:R01806 +xref: MetaCyc:2.3.1.44-RXN +xref: RHEA:18305 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047186 +name: N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA." [EC:2.3.1.45, MetaCyc:2.3.1.45-RXN] +synonym: "acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "glycoprotein 7(9)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "N-acetylneuraminate 7(8)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "N-acetylneuraminate 7,8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "N-acetylneuraminate O7-(or O9-)acetyltransferase activity" EXACT [EC:2.3.1.45] +synonym: "sialate O-acetyltransferase" BROAD [EC:2.3.1.45] +xref: EC:2.3.1.45 +xref: MetaCyc:2.3.1.45-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047187 +name: deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate." [EC:2.3.1.49, MetaCyc:2.3.1.49-RXN] +synonym: "deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity" EXACT [EC:2.3.1.49] +synonym: "deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity" EXACT [EC:2.3.1.49] +synonym: "S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity" EXACT [EC:2.3.1.49] +synonym: "S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity" EXACT [EC:2.3.1.49] +xref: EC:2.3.1.49 +xref: MetaCyc:2.3.1.49-RXN +is_a: GO:0016418 ! S-acetyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0047188 +name: aromatic-hydroxylamine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl." [EC:2.3.1.56, MetaCyc:2.3.1.56-RXN] +synonym: "aromatic hydroxylamine acetyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "arylhydroxamate acyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "arylhydroxamic acid N,O-acetyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "arylhydroxamic acyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "N,O-acetyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity" EXACT [EC:2.3.1.56] +synonym: "N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity" EXACT [EC:2.3.1.56] +xref: EC:2.3.1.56 +xref: MetaCyc:2.3.1.56-RXN +xref: RHEA:20325 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047189 +name: 2,3-diaminopropionate N-oxalyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA." [EC:2.3.1.58, RHEA:13465] +synonym: "ODAP synthase activity" EXACT [EC:2.3.1.58] +synonym: "oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity" EXACT [EC:2.3.1.58] +synonym: "oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity" EXACT [EC:2.3.1.58] +synonym: "oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity" EXACT [EC:2.3.1.58] +synonym: "oxalyldiaminopropionate synthase activity" EXACT [EC:2.3.1.58] +synonym: "oxalyldiaminopropionic synthase activity" EXACT [EC:2.3.1.58] +xref: EC:2.3.1.58 +xref: KEGG_REACTION:R04211 +xref: MetaCyc:2.3.1.58-RXN +xref: RHEA:13465 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047190 +name: 2-acylglycerophosphocholine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA." [EC:2.3.1.62, RHEA:10332] +synonym: "2-acylglycerol-3-phosphorylcholine acyltransferase activity" EXACT [EC:2.3.1.62] +synonym: "2-acylglycerophosphocholine acyltransferase activity" EXACT [EC:2.3.1.62] +synonym: "acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.62] +xref: EC:2.3.1.62 +xref: KEGG_REACTION:R01319 +xref: MetaCyc:2.3.1.62-RXN +xref: RHEA:10332 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047191 +name: 1-alkylglycerophosphocholine O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA." [EC:2.3.1.63, MetaCyc:2.3.1.63-RXN] +synonym: "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.63] +xref: EC:2.3.1.63 +xref: MetaCyc:2.3.1.63-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047192 +name: 1-alkylglycerophosphocholine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA." [EC:2.3.1.67, MetaCyc:2.3.1.67-RXN] +synonym: "1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "1-alkyl-2-lysolecithin acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "acetyl-CoA:lyso-PAF acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "blood platelet-activating factor acetyltransferase activity" BROAD [EC:2.3.1.67] +synonym: "lyso-GPC:acetyl CoA acetyltransferase activity" BROAD [EC:2.3.1.67] +synonym: "lyso-platelet activating factor:acetyl-CoA acetyltransferase activity" BROAD [EC:2.3.1.67] +synonym: "lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity" BROAD [EC:2.3.1.67] +synonym: "lysoPAF:acetyl CoA acetyltransferase activity" EXACT [EC:2.3.1.67] +synonym: "lysopaf:acetyl CoA acetyltransferase activity" BROAD [EC:2.3.1.67] +synonym: "platelet-activating factor acylhydrolase activity" BROAD [EC:2.3.1.67] +synonym: "platelet-activating factor-synthesizing enzyme activity" BROAD [EC:2.3.1.67] +xref: EC:2.3.1.67 +xref: MetaCyc:2.3.1.67-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047193 +name: obsolete CDP-acylglycerol O-arachidonoyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA." [EC:2.3.1.70, MetaCyc:2.3.1.70-RXN] +comment: This term was made obsolete because the evidence for the existence of this reaction was retracted. Please see PMID:6885763 for more information. +synonym: "arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity" EXACT [EC:2.3.1.70] +synonym: "arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity" EXACT [EC:2.3.1.70] +synonym: "CDP-acylglycerol O-arachidonoyltransferase activity" EXACT [] +synonym: "CDP-acylglycerol O-arachidonyltransferase activity" EXACT [] +synonym: "CDPacylglycerol O-arachidonyltransferase activity" EXACT [EC:2.3.1.70] +xref: MetaCyc:2.3.1.70-RXN +is_obsolete: true + +[Term] +id: GO:0047194 +name: indoleacetylglucose-inositol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose." [EC:2.3.1.72, RHEA:21180] +synonym: "1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity" EXACT [EC:2.3.1.72] +synonym: "1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity" EXACT [EC:2.3.1.72] +synonym: "indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity" EXACT [EC:2.3.1.72] +xref: EC:2.3.1.72 +xref: KEGG_REACTION:R04333 +xref: MetaCyc:2.3.1.72-RXN +xref: RHEA:21180 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047195 +name: diacylglycerol-sterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol." [EC:2.3.1.73, MetaCyc:2.3.1.73-RXN] +synonym: "1,2-diacyl-sn-glycerol:sterol acyl transferase activity" EXACT [EC:2.3.1.73] +synonym: "1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity" EXACT [EC:2.3.1.73] +xref: EC:2.3.1.73 +xref: MetaCyc:2.3.1.73-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047196 +name: long-chain-alcohol O-fatty-acyltransferase activity +namespace: molecular_function +alt_id: GO:0103095 +def: "Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA." [EC:2.3.1.75, MetaCyc:2.3.1.75-RXN] +synonym: "acyl-CoA:long-chain-alcohol O-acyltransferase activity" EXACT [EC:2.3.1.75] +synonym: "wax ester synthase activity" EXACT [] +synonym: "wax synthase activity" RELATED [EC:2.3.1.75] +synonym: "wax-ester synthase activity" EXACT [EC:2.3.1.75] +xref: EC:2.3.1.75 +xref: MetaCyc:2.3.1.75-RXN +xref: MetaCyc:RXNQT-4193 +xref: Reactome:R-HSA-5696424 "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters" +xref: Reactome:R-HSA-8848582 "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester" +xref: RHEA:38443 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047197 +name: triglyceride-sterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol." [EC:2.3.1.77, MetaCyc:2.3.1.77-RXN] +synonym: "triacylglycerol-sterol O-acyltransferase activity" EXACT [] +synonym: "triacylglycerol:3beta-hydroxysterol O-acyltransferase activity" EXACT [EC:2.3.1.77] +synonym: "triacylglycerol:sterol acyltransferase activity" EXACT [EC:2.3.1.77] +xref: EC:2.3.1.77 +xref: MetaCyc:2.3.1.77-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047198 +name: cysteine-S-conjugate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+)." [EC:2.3.1.80, RHEA:19213] +synonym: "acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity" EXACT [EC:2.3.1.80] +xref: EC:2.3.1.80 +xref: KEGG_REACTION:R04950 +xref: MetaCyc:2.3.1.80-RXN +xref: Reactome:R-HSA-5433066 "Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C" +xref: RHEA:19213 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047199 +name: phosphatidylcholine-dolichol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol." [EC:2.3.1.83, RHEA:19285] +synonym: "3-sn-phosphatidylcholine:dolichol O-acyltransferase activity" EXACT [EC:2.3.1.83] +xref: EC:2.3.1.83 +xref: KEGG_REACTION:R04227 +xref: MetaCyc:2.3.1.83-RXN +xref: RHEA:19285 +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047200 +name: tetrahydrodipicolinate N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA." [EC:2.3.1.89, RHEA:13085] +synonym: "acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity" EXACT [EC:2.3.1.89] +synonym: "acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity" EXACT [EC:2.3.1.89] +synonym: "acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity" EXACT [EC:2.3.1.89] +synonym: "tetrahydrodipicolinate acetylase activity" EXACT [EC:2.3.1.89] +synonym: "tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.89] +xref: EC:2.3.1.89 +xref: KEGG_REACTION:R04364 +xref: MetaCyc:2.3.1.89-RXN +xref: RHEA:13085 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047201 +name: beta-glucogallin O-galloyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose." [EC:2.3.1.90, RHEA:11416] +synonym: "1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity" EXACT [EC:2.3.1.90] +xref: EC:2.3.1.90 +xref: KEGG_REACTION:R00049 +xref: MetaCyc:2.3.1.90-RXN +xref: RHEA:11416 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047202 +name: sinapoylglucose-choline O-sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose." [EC:2.3.1.91, RHEA:12024] +synonym: "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity" EXACT [EC:2.3.1.91] +synonym: "sinapine synthase activity" EXACT [EC:2.3.1.91] +xref: EC:2.3.1.91 +xref: KEGG_REACTION:R03075 +xref: MetaCyc:2.3.1.91-RXN +xref: RHEA:12024 +is_a: GO:0016753 ! O-sinapoyltransferase activity + +[Term] +id: GO:0047203 +name: 13-hydroxylupinine O-tigloyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA." [EC:2.3.1.93, RHEA:12360] +synonym: "(E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity" EXACT [EC:2.3.1.93] +synonym: "13-hydroxylupanine acyltransferase activity" EXACT [EC:2.3.1.93] +synonym: "tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity" EXACT [EC:2.3.1.93] +xref: EC:2.3.1.93 +xref: KEGG_REACTION:R04205 +xref: MetaCyc:2.3.1.93-RXN +xref: RHEA:12360 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047204 +name: chlorogenate-glucarate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate." [EC:2.3.1.98, RHEA:23204] +synonym: "chlorogenate:glucarate caffeoyltransferase activity" EXACT [EC:2.3.1.98] +synonym: "chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.98] +synonym: "chlorogenic acid:glucaric acid O-caffeoyltransferase activity" EXACT [EC:2.3.1.98] +xref: EC:2.3.1.98 +xref: KEGG_REACTION:R02998 +xref: MetaCyc:2.3.1.98-RXN +xref: RHEA:23204 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047205 +name: quinate O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA." [EC:2.3.1.99, MetaCyc:2.3.1.99-RXN] +synonym: "feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.99] +synonym: "hydroxycinnamoyl coenzyme A-quinate transferase activity" EXACT [EC:2.3.1.99] +xref: EC:2.3.1.99 +xref: MetaCyc:2.3.1.99-RXN +xref: RHEA:15021 +is_a: GO:0050737 ! O-hydroxycinnamoyltransferase activity + +[Term] +id: GO:0047206 +name: UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA." [EC:2.3.2.10, MetaCyc:2.3.2.10-RXN] +synonym: "alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity" EXACT [EC:2.3.2.10] +synonym: "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity" EXACT [EC:2.3.2.10] +synonym: "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] +synonym: "UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity" EXACT [EC:2.3.2.10] +synonym: "UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] +synonym: "uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity" EXACT [EC:2.3.2.10] +synonym: "uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] +xref: EC:2.3.2.10 +xref: MetaCyc:2.3.2.10-RXN +xref: RHEA:12432 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0047207 +name: 1,2-beta-fructan 1F-fructosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1)." [EC:2.4.1.100, MetaCyc:2.4.1.100-RXN] +synonym: "1,2-beta-D-fructan 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "1,2-beta-D-fructan 1F-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "1,2-beta-fructan 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "2,1-fructan:2,1-fructan 1-fructosyltransferase activity" EXACT [EC:2.4.1.100] +synonym: "FFT activity" EXACT [EC:2.4.1.100] +synonym: "fructan:fructan fructosyl transferase activity" EXACT [EC:2.4.1.100] +xref: EC:2.4.1.100 +xref: MetaCyc:2.4.1.100-RXN +is_a: GO:0050738 ! fructosyltransferase activity + +[Term] +id: GO:0047208 +name: o-dihydroxycoumarin 7-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP." [EC:2.4.1.104, RHEA:14325] +synonym: "UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.104] +synonym: "UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity" EXACT [EC:2.4.1.104] +synonym: "UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.104] +synonym: "uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.104] +xref: EC:2.4.1.104 +xref: KEGG_REACTION:R03548 +xref: MetaCyc:2.4.1.104-RXN +xref: RHEA:14325 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047209 +name: coniferyl-alcohol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP." [EC:2.4.1.111, MetaCyc:2.4.1.111-RXN] +synonym: "UDP-glucose coniferyl alcohol glucosyltransferase activity" EXACT [EC:2.4.1.111] +synonym: "UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.111] +synonym: "UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.111] +synonym: "uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity" EXACT [EC:2.4.1.111] +xref: EC:2.4.1.111 +xref: MetaCyc:2.4.1.111-RXN +xref: RHEA:23944 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047211 +name: alpha-1,4-glucan-protein synthase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP." [EC:2.4.1.113, MetaCyc:2.4.1.113-RXN] +synonym: "1,4alpha-glucan-protein synthase (ADP-forming) activity" EXACT [] +synonym: "adenosine diphosphoglucose-protein glucosyltransferase activity" EXACT [EC:2.4.1.113] +synonym: "ADP-glucose:protein 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.113] +synonym: "ADPglucose:protein 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.113] +synonym: "ADPglucose:protein glucosyltransferase activity" EXACT [EC:2.4.1.113] +xref: EC:2.4.1.113 +xref: MetaCyc:2.4.1.113-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0047212 +name: 2-coumarate O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP." [EC:2.4.1.114, RHEA:10236] +synonym: "UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.114] +synonym: "UDPG:o-coumaric acid O-glucosyltransferase activity" EXACT [EC:2.4.1.114] +synonym: "UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.114] +synonym: "uridine diphosphoglucose-o-coumarate glucosyltransferase activity" EXACT [EC:2.4.1.114] +xref: EC:2.4.1.114 +xref: KEGG_REACTION:R03710 +xref: MetaCyc:2.4.1.114-RXN +xref: RHEA:10236 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047213 +name: anthocyanidin 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP." [EC:2.4.1.115, MetaCyc:2.4.1.115-RXN] +synonym: "3-GT activity" EXACT [EC:2.4.1.115] +synonym: "UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.115] +synonym: "UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.115] +synonym: "UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] +synonym: "UDP-glucose:cyanidin-3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] +synonym: "uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] +xref: EC:2.4.1.115 +xref: MetaCyc:2.4.1.115-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047214 +name: cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP." [EC:2.4.1.116, MetaCyc:2.4.1.116-RXN] +synonym: "cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity" EXACT [EC:2.4.1.116] +synonym: "UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.116] +synonym: "UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.116] +synonym: "uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity" EXACT [EC:2.4.1.116] +xref: EC:2.4.1.116 +xref: MetaCyc:2.4.1.116-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047215 +name: indole-3-acetate beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP." [EC:2.4.1.121, RHEA:14921] +synonym: "IAA-Glu synthetase activity" EXACT [EC:2.4.1.121] +synonym: "IAA-glucose synthase activity" EXACT [EC:2.4.1.121] +synonym: "IAGlu synthase activity" EXACT [EC:2.4.1.121] +synonym: "indol-3-ylacetylglucose synthase activity" EXACT [EC:2.4.1.121] +synonym: "UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.121] +synonym: "UDP-glucose:auxin glucosyltransferase activity" BROAD [] +synonym: "UDP-glucose:indol-3-acetic acid glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:indol-3-ylacetate glucosyl-transferase activity" EXACT [EC:2.4.1.121] +synonym: "UDP-glucose:indol-3-ylacetate glucosyltransferase activity" EXACT [EC:2.4.1.121] +synonym: "UDPG-indol-3-ylacetyl glucosyl transferase activity" EXACT [EC:2.4.1.121] +synonym: "UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.121] +synonym: "uridine diphosphoglucose-indoleacetate glucosyltransferase activity" EXACT [EC:2.4.1.121] +xref: EC:2.4.1.121 +xref: KEGG_REACTION:R03094 +xref: MetaCyc:2.4.1.121-RXN +xref: RHEA:14921 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047216 +name: inositol 3-alpha-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP." [EC:2.4.1.123, MetaCyc:2.4.1.123-RXN] +synonym: "galactinol synthase activity" EXACT [EC:2.4.1.123] +synonym: "inositol 1-alpha-galactosyltransferase activity" EXACT [] +synonym: "UDP-D-galactose:inositol galactosyltransferase activity" EXACT [EC:2.4.1.123] +synonym: "UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] +synonym: "UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] +synonym: "UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] +synonym: "uridine diphosphogalactose-inositol galactosyltransferase activity" EXACT [EC:2.4.1.123] +xref: EC:2.4.1.123 +xref: MetaCyc:2.4.1.123-RXN +xref: RHEA:12464 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047217 +name: sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose." [EC:2.4.1.125, MetaCyc:2.4.1.125-RXN] +synonym: "GTF-S" RELATED [EC:2.4.1.125] +synonym: "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase" BROAD [EC:2.4.1.125] +synonym: "sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.125] +synonym: "sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.125] +synonym: "water-soluble-glucan synthase activity" RELATED [EC:2.4.1.125] +xref: EC:2.4.1.125 +xref: MetaCyc:2.4.1.125-RXN +is_a: GO:0046527 ! glucosyltransferase activity + +[Term] +id: GO:0047218 +name: hydroxycinnamate 4-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP." [EC:2.4.1.126, MetaCyc:2.4.1.126-RXN] +synonym: "hydroxycinnamoyl glucosyltransferase activity" EXACT [EC:2.4.1.126] +synonym: "UDP-glucose-hydroxycinnamate glucosyltransferase activity" EXACT [EC:2.4.1.126] +synonym: "UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.126] +synonym: "UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.126] +synonym: "uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity" EXACT [EC:2.4.1.126] +xref: EC:2.4.1.126 +xref: MetaCyc:2.4.1.126-RXN +xref: RHEA:21636 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047219 +name: monoterpenol beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP." [EC:2.4.1.127, RHEA:11520] +synonym: "UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.127] +synonym: "UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.127] +synonym: "UDPglucose:monoterpenol glucosyltransferase activity" EXACT [EC:2.4.1.127] +synonym: "uridine diphosphoglucose-monoterpenol glucosyltransferase activity" EXACT [EC:2.4.1.127] +xref: EC:2.4.1.127 +xref: KEGG_REACTION:R02179 +xref: MetaCyc:2.4.1.127-RXN +xref: RHEA:11520 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047220 +name: galactosylxylosylprotein 3-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP." [EC:2.4.1.134, MetaCyc:2.4.1.134-RXN] +synonym: "galactosyltransferase II activity" RELATED [EC:2.4.1.134] +synonym: "UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.134] +synonym: "UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.134] +synonym: "uridine diphosphogalactose-galactosylxylose galactosyltransferase activity" EXACT [EC:2.4.1.134] +xref: EC:2.4.1.134 +xref: MetaCyc:2.4.1.134-RXN +xref: Reactome:R-HSA-1889978 "B3GALT6 transfers Gal to the tetrasaccharide linker" +xref: Reactome:R-HSA-4420365 "Defective B3GALT6 does not transfer Gal to the tetrasaccharide linker" +is_a: GO:0035250 ! UDP-galactosyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047221 +name: sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP." [EC:2.4.1.137, RHEA:14285] +synonym: "floridoside phosphate synthase activity" EXACT [EC:2.4.1.137] +synonym: "floridoside phosphate synthetase activity" EXACT [EC:2.4.1.137] +synonym: "floridoside-phosphate synthase activity" EXACT [EC:2.4.1.137] +synonym: "FPS" RELATED [EC:2.4.1.137] +synonym: "UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity" EXACT [EC:2.4.1.137] +synonym: "UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.137] +synonym: "UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity" EXACT [EC:2.4.1.137] +synonym: "UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.137] +xref: EC:2.4.1.137 +xref: KEGG_REACTION:R00853 +xref: MetaCyc:2.4.1.137-RXN +xref: RHEA:14285 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047222 +name: mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP." [EC:2.4.1.138, MetaCyc:2.4.1.138-RXN] +synonym: "alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.138] +synonym: "UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.138] +synonym: "uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity" EXACT [EC:2.4.1.138] +xref: EC:2.4.1.138 +xref: MetaCyc:2.4.1.138-RXN +xref: RHEA:13705 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0047223 +name: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.146, MetaCyc:2.4.1.146-RXN] +synonym: "elongation 3-beta-GalNAc-transferase activity" RELATED [EC:2.4.1.146] +synonym: "elongation 3beta-GalNAc-transferase activity" EXACT [EC:2.4.1.146] +synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.146] +synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.146] +synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)" EXACT [EC:2.4.1.146] +xref: EC:2.4.1.146 +xref: MetaCyc:2.4.1.146-RXN +xref: Reactome:R-HSA-5617037 "POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1" +xref: Reactome:R-HSA-5617096 "Defective POMGNT1 does not transfer GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1" +xref: RHEA:12227 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047224 +name: acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.147, MetaCyc:2.4.1.147-RXN] +synonym: "core 3-beta-GlcNAc-transferase activity" RELATED [EC:2.4.1.147] +synonym: "core 3beta-GlcNAc-transferase activity" EXACT [EC:2.4.1.147] +synonym: "mucin core 3 beta3-GlcNAc-transferase activity" EXACT [EC:2.4.1.147] +synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.147] +synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.147] +synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.147] +xref: EC:2.4.1.147 +xref: MetaCyc:2.4.1.147-RXN +xref: RHEA:14252 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047225 +name: acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.148, MetaCyc:2.4.1.148-RXN] +synonym: "core 4 beta6-GalNAc-transferase activity" EXACT [EC:2.4.1.148] +synonym: "core 6-beta-GalNAc-transferase B activity" RELATED [EC:2.4.1.148] +synonym: "core 6beta-GalNAc-transferase B" RELATED [EC:2.4.1.148] +synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.148] +synonym: "UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.148] +synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B" RELATED [EC:2.4.1.148] +xref: EC:2.4.1.148 +xref: MetaCyc:2.4.1.148-RXN +xref: RHEA:16552 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047227 +name: indolylacetyl-myo-inositol galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP." [EC:2.4.1.156, RHEA:21148] +synonym: "indol-3-ylacetyl-myo-inositol galactoside synthase activity" EXACT [EC:2.4.1.156] +synonym: "UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity" EXACT [EC:2.4.1.156] +synonym: "UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity" EXACT [EC:2.4.1.156] +synonym: "uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity" EXACT [EC:2.4.1.156] +xref: EC:2.4.1.156 +xref: KEGG_REACTION:R04334 +xref: MetaCyc:2.4.1.156-RXN +xref: RHEA:21148 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047228 +name: 1,2-diacylglycerol 3-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP." [EC:2.4.1.157, MetaCyc:2.4.1.157-RXN] +synonym: "UDP-glucose-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] +synonym: "UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity" EXACT [EC:2.4.1.157] +synonym: "UDP-glucose:1,2-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] +synonym: "UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity" EXACT [EC:2.4.1.157] +synonym: "UDPglucose:diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] +synonym: "uridine diphosphoglucose-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] +xref: EC:2.4.1.157 +xref: MetaCyc:2.4.1.157-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047229 +name: 13-hydroxydocosanoate 13-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP." [EC:2.4.1.158, MetaCyc:2.4.1.158-RXN] +synonym: "13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity" EXACT [EC:2.4.1.158] +synonym: "UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity" EXACT [EC:2.4.1.158] +synonym: "UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.158] +synonym: "UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity" EXACT [EC:2.4.1.158] +synonym: "UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.158] +synonym: "uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity" EXACT [EC:2.4.1.158] +xref: EC:2.4.1.158 +xref: MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN +xref: RHEA:22316 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047230 +name: flavonol-3-O-glucoside L-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP." [EC:2.4.1.159, MetaCyc:2.4.1.159-RXN] +synonym: "UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity" EXACT [EC:2.4.1.159] +synonym: "UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity" EXACT [EC:2.4.1.159] +synonym: "uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity" EXACT [EC:2.4.1.159] +xref: EC:2.4.1.159 +xref: MetaCyc:2.4.1.159-RXN +xref: RHEA:22528 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047231 +name: pyridoxine 5'-O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP." [EC:2.4.1.160, RHEA:20177] +synonym: "UDP-glucose-pyridoxine glucosyltransferase activity" EXACT [EC:2.4.1.160] +synonym: "UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.160] +synonym: "UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity" EXACT [EC:2.4.1.160] +synonym: "UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.160] +synonym: "uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity" EXACT [EC:2.4.1.160] +xref: EC:2.4.1.160 +xref: KEGG_REACTION:R01912 +xref: MetaCyc:2.4.1.160-RXN +xref: RHEA:20177 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047232 +name: galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP." [EC:2.4.1.164, MetaCyc:2.4.1.164-RXN] +synonym: "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.164] +synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase" BROAD [EC:2.4.1.164] +xref: EC:2.4.1.164 +xref: MetaCyc:2.4.1.164-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0047233 +name: N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP." [EC:2.4.1.165, MetaCyc:2.4.1.165-RXN] +synonym: "UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.165] +synonym: "uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.165] +xref: EC:2.4.1.165 +xref: MetaCyc:2.4.1.165-RXN +xref: RHEA:13569 +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0047234 +name: raffinose-raffinose alpha-galactotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose." [EC:2.4.1.166, MetaCyc:2.4.1.166-RXN] +synonym: "raffinose (raffinose donor) galactosyltransferase activity" EXACT [EC:2.4.1.166] +synonym: "raffinose-raffinose a-galactosyltransferase activity" EXACT [] +synonym: "raffinose-raffinose alpha-galactosyltransferase activity" EXACT [] +synonym: "raffinose:raffinose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.166] +synonym: "raffinose:raffinose alpha-galactosyltransferase activity" EXACT [EC:2.4.1.166] +xref: EC:2.4.1.166 +xref: MetaCyc:2.4.1.166-RXN +xref: RHEA:14125 +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0047235 +name: sucrose 6F-alpha-galactotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP." [EC:2.4.1.167, MetaCyc:2.4.1.167-RXN] +synonym: "sucrose 6(F)-alpha-galactosyltransferase activity" EXACT [] +synonym: "sucrose 6F-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] +synonym: "UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.167] +synonym: "UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.167] +synonym: "UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] +synonym: "uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] +xref: EC:2.4.1.167 +xref: MetaCyc:2.4.1.167-RXN +xref: RHEA:10088 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047236 +name: methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP." [EC:2.4.1.171, MetaCyc:2.4.1.171-RXN] +synonym: "cycasin synthase activity" EXACT [EC:2.4.1.171] +synonym: "methyl-ONN-azoxymethanol glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.171] +synonym: "UDPglucose-methylazoxymethanol glucosyltransferase activity" EXACT [EC:2.4.1.171] +synonym: "uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity" EXACT [EC:2.4.1.171] +xref: EC:2.4.1.171 +xref: MetaCyc:2.4.1.171-RXN +xref: RHEA:20205 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047237 +name: glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP." [EC:2.4.1.174, MetaCyc:2.4.1.174-RXN] +synonym: "glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] +synonym: "N-acetylgalactosaminyltransferase I activity" EXACT [] +synonym: "UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.174] +synonym: "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I" RELATED [EC:2.4.1.174] +synonym: "uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity" EXACT [EC:2.4.1.174] +xref: EC:2.4.1.174 +xref: MetaCyc:2.4.1.174-RXN +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0047238 +name: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP." [EC:2.4.1.175, MetaCyc:2.4.1.175-RXN] +synonym: "chondroitin synthase activity" EXACT [EC:2.4.1.175] +synonym: "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT [] +synonym: "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] +synonym: "N-acetylgalactosaminyltransferase II activity" EXACT [] +synonym: "UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.175] +synonym: "UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.175] +synonym: "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity" EXACT [EC:2.4.1.175] +xref: EC:2.4.1.175 +xref: MetaCyc:2.4.1.175-RXN +xref: Reactome:R-HSA-1971482 "The addition of GalNAc to the terminal glucuronate residue forms chondroitin" +xref: Reactome:R-HSA-1971487 "CHPF,CHSY3 transfer GalNAc to chondroitin" +xref: Reactome:R-HSA-3595176 "Defective CHSY1 does not transfer GalNAc to chondroitin" +xref: Reactome:R-HSA-9632033 "CHSY1 transfers GalNAc to chondroitin" +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0047239 +name: hydroxymandelonitrile glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP." [EC:2.4.1.178, RHEA:15961] +synonym: "cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.178] +synonym: "UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.178] +synonym: "UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.178] +xref: EC:2.4.1.178 +xref: KEGG_REACTION:R02709 +xref: MetaCyc:2.4.1.178-RXN +xref: RHEA:15961 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047240 +name: lactosylceramide beta-1,3-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP." [EC:2.4.1.179, RHEA:18413] +synonym: "UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.179] +synonym: "UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.179] +synonym: "uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity" EXACT [EC:2.4.1.179] +xref: EC:2.4.1.179 +xref: KEGG_REACTION:R04431 +xref: MetaCyc:2.4.1.179-RXN +xref: RHEA:18413 +is_a: GO:0035250 ! UDP-galactosyltransferase activity +is_a: GO:0048531 ! beta-1,3-galactosyltransferase activity + +[Term] +id: GO:0047241 +name: lipopolysaccharide N-acetylmannosaminouronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP." [RHEA:28366] +synonym: "LPS N-acetylmannosaminouronosyltransferase activity" EXACT [] +synonym: "ManNAcA transferase activity" EXACT [EC:2.4.1.180] +synonym: "UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity" EXACT [EC:2.4.1.180] +synonym: "uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity" EXACT [EC:2.4.1.180] +xref: EC:2.4.1.180 +xref: MetaCyc:2.4.1.180-RXN +xref: RHEA:28366 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047242 +name: hydroxyanthraquinone glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP." [EC:2.4.1.181, MetaCyc:2.4.1.181-RXN] +synonym: "anthraquinone-specific glucosyltransferase activity" EXACT [EC:2.4.1.181] +synonym: "UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity" EXACT [EC:2.4.1.181] +synonym: "UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity" EXACT [EC:2.4.1.181] +synonym: "uridine diphosphoglucose-anthraquinone glucosyltransferase activity" EXACT [EC:2.4.1.181] +xref: EC:2.4.1.181 +xref: MetaCyc:2.4.1.181-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047243 +name: flavanone 7-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP." [EC:2.4.1.185, MetaCyc:2.4.1.185-RXN] +synonym: "hesperetin 7-O-glucosyl-transferase activity" EXACT [EC:2.4.1.185] +synonym: "naringenin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.185] +synonym: "UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.185] +synonym: "UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.185] +synonym: "uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.185] +xref: EC:2.4.1.185 +xref: MetaCyc:2.4.1.185-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047244 +name: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP." [EC:2.4.1.187, MetaCyc:2.4.1.187-RXN] +synonym: "N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] +synonym: "UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] +synonym: "UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] +synonym: "uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] +xref: EC:2.4.1.187 +xref: MetaCyc:TEICHOICSYN2-RXN +xref: RHEA:16053 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047245 +name: N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP." [EC:2.4.1.188, MetaCyc:2.4.1.188-RXN] +synonym: "UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity" EXACT [EC:2.4.1.188] +synonym: "UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.188] +synonym: "UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.188] +synonym: "uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity" EXACT [EC:2.4.1.188] +xref: EC:2.4.1.188 +xref: MetaCyc:2.4.1.188-RXN +xref: RHEA:20952 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047246 +name: luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP." [EC:2.4.1.190, RHEA:14149] +synonym: "LMT activity" RELATED [EC:2.4.1.190] +synonym: "luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] +synonym: "UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] +synonym: "UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] +synonym: "uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity" EXACT [EC:2.4.1.190] +xref: EC:2.4.1.190 +xref: KEGG_REACTION:R06827 +xref: MetaCyc:2.4.1.190-RXN +xref: RHEA:14149 +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0047247 +name: luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP." [EC:2.4.1.191, RHEA:22116] +synonym: "LDT" RELATED [EC:2.4.1.191] +synonym: "UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] +synonym: "UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] +synonym: "UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity" EXACT [EC:2.4.1.191] +synonym: "UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] +synonym: "uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity" EXACT [EC:2.4.1.191] +xref: EC:2.4.1.191 +xref: KEGG_REACTION:R06828 +xref: MetaCyc:2.4.1.191-RXN +xref: RHEA:22116 +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0047248 +name: nuatigenin 3-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP." [EC:2.4.1.192, RHEA:19329] +synonym: "nuatigenin 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.192] +synonym: "UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.192] +synonym: "UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.192] +synonym: "uridine diphosphoglucose-nuatigenin glucosyltransferase activity" EXACT [EC:2.4.1.192] +xref: EC:2.4.1.192 +xref: KEGG_REACTION:R04577 +xref: MetaCyc:2.4.1.192-RXN +xref: RHEA:19329 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047249 +name: sarsapogenin 3-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP." [EC:2.4.1.193, RHEA:14461] +synonym: "sarsapogenin 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.193] +synonym: "UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.193] +synonym: "UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.193] +synonym: "uridine diphosphoglucose-sarsapogenin glucosyltransferase activity" EXACT [EC:2.4.1.193] +xref: EC:2.4.1.193 +xref: KEGG_REACTION:R04359 +xref: MetaCyc:2.4.1.193-RXN +xref: RHEA:14461 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047250 +name: 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP." [EC:2.4.1.194, RHEA:15153] +synonym: "HBA glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "p-hydroxybenzoate glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "PHB glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "PHB-O-glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.194] +synonym: "uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity" EXACT [EC:2.4.1.194] +xref: EC:2.4.1.194 +xref: KEGG_REACTION:R01304 +xref: MetaCyc:2.4.1.194-RXN +xref: RHEA:15153 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047251 +name: thiohydroximate beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP." [EC:2.4.1.195, MetaCyc:2.4.1.195-RXN] +synonym: "desulfoglucosinolate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "N-hydroxythioamide S-beta-glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "thiohydroximate S-glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "UDPG:thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] +synonym: "uridine diphosphoglucose-thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] +xref: EC:2.4.1.195 +xref: MetaCyc:2.4.1.195-RXN +xref: RHEA:13757 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047252 +name: beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate." [EC:2.4.1.199, MetaCyc:2.4.1.199-RXN] +synonym: "beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.199] +synonym: "mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity" EXACT [EC:2.4.1.199] +xref: EC:2.4.1.199 +xref: MetaCyc:2.4.1.199-RXN +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0047253 +name: alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP." [EC:2.4.1.201, MetaCyc:2.4.1.201-RXN] +synonym: "alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity" EXACT [] +synonym: "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.201] +synonym: "N-acetylglucosaminyltransferase VI activity" RELATED [EC:2.4.1.201] +synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity" EXACT [EC:2.4.1.201] +synonym: "UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.201] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI" RELATED [EC:2.4.1.201] +synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity" EXACT [EC:2.4.1.201] +xref: EC:2.4.1.201 +xref: MetaCyc:2.4.1.201-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047254 +name: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP." [EC:2.4.1.202, MetaCyc:2.4.1.202-RXN] +synonym: "UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity" EXACT [EC:2.4.1.202] +synonym: "UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity" EXACT [EC:2.4.1.202] +synonym: "uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity" EXACT [EC:2.4.1.202] +xref: EC:2.4.1.202 +xref: MetaCyc:2.4.1.202-RXN +xref: RHEA:15541 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047255 +name: galactogen 6-beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP." [EC:2.4.1.205, MetaCyc:2.4.1.205-RXN] +synonym: "1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] +synonym: "beta-(1,6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] +synonym: "galactogen 6beta-galactosyltransferase activity" EXACT [EC:2.4.1.205] +synonym: "UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] +synonym: "UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] +synonym: "uridine diphosphogalactose-galactogen galactosyltransferase activity" EXACT [EC:2.4.1.205] +xref: EC:2.4.1.205 +xref: MetaCyc:2.4.1.205-RXN +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047256 +name: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP." [EC:2.4.1.206, MetaCyc:2.4.1.206-RXN] +synonym: "beta1->3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] +synonym: "LA2 synthase activity" EXACT [EC:2.4.1.206] +synonym: "lactosylceramide beta-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] +synonym: "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] +synonym: "uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] +xref: EC:2.4.1.206 +xref: MetaCyc:2.4.1.206-RXN +xref: RHEA:13905 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0047257 +name: diglucosyl diacylglycerol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol." [EC:2.4.1.208, MetaCyc:2.4.1.208-RXN] +synonym: "DGlcDAG synthase activity" EXACT [EC:2.4.1.208] +synonym: "diglucosyl diacylglycerol (DGlcDAG) synthase activity" EXACT [] +synonym: "MGlcDAG (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] +synonym: "monoglucosyl diacylglycerol (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] +synonym: "UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] +xref: EC:2.4.1.208 +xref: MetaCyc:2.4.1.208-RXN +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047258 +name: sphingosine beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP." [EC:2.4.1.23, RHEA:19485] +synonym: "galactosyl-sphingosine transferase activity" EXACT [EC:2.4.1.23] +synonym: "psychosine-UDP galactosyltransferase activity" EXACT [EC:2.4.1.23] +synonym: "psychosine-uridine diphosphate galactosyltransferase activity" EXACT [EC:2.4.1.23] +synonym: "UDP-galactose:sphingosine 1-beta-galactotransferase activity" EXACT [EC:2.4.1.23] +synonym: "UDPgalactose:sphingosine 1-beta-galactotransferase activity" EXACT [EC:2.4.1.23] +synonym: "UDPgalactose:sphingosine O-galactosyl transferase activity" EXACT [EC:2.4.1.23] +synonym: "uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity" EXACT [EC:2.4.1.23] +xref: EC:2.4.1.23 +xref: KEGG_REACTION:R01928 +xref: MetaCyc:2.4.1.23-RXN +xref: RHEA:19485 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047259 +name: glucomannan 4-beta-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP." [EC:2.4.1.32, MetaCyc:2.4.1.32-RXN] +synonym: "GDP-man-beta-mannan mannosyltransferase activity" EXACT [EC:2.4.1.32] +synonym: "GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity" EXACT [] +synonym: "glucomannan 4-b-mannosyltransferase activity" EXACT [] +synonym: "glucomannan-synthase activity" EXACT [] +xref: EC:2.4.1.32 +xref: MetaCyc:2.4.1.32-RXN +is_a: GO:0019187 ! beta-1,4-mannosyltransferase activity + +[Term] +id: GO:0047260 +name: alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP." [EC:2.4.1.36, MetaCyc:2.4.1.36-RXN] +synonym: "GDP-glucose-glucosephosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] +synonym: "GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.36] +synonym: "GDPglucose-glucose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] +synonym: "GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.36] +synonym: "guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] +synonym: "trehalose phosphate synthase (GDP-forming) activity" EXACT [EC:2.4.1.36] +xref: EC:2.4.1.36 +xref: MetaCyc:2.4.1.36-RXN +xref: RHEA:14605 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047261 +name: steroid N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP." [EC:2.4.1.39, RHEA:14153] +synonym: "hydroxy steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] +synonym: "steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] +synonym: "UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] +synonym: "uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] +xref: EC:2.4.1.39 +xref: KEGG_REACTION:R04451 +xref: MetaCyc:2.4.1.39-RXN +xref: RHEA:14153 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0047262 +name: polygalacturonate 4-alpha-galacturonosyltransferase activity +namespace: molecular_function +alt_id: GO:0050375 +def: "Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP." [EC:2.4.1.43, MetaCyc:2.4.1.43-RXN] +synonym: "UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] +synonym: "UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] +synonym: "uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] +xref: EC:2.4.1.43 +xref: MetaCyc:2.4.1.43-RXN +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047263 +name: N-acylsphingosine galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP." [EC:2.4.1.47, MetaCyc:2.4.1.47-RXN] +synonym: "UDP galactose-N-acylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.47] +synonym: "UDP-galactose:N-acylsphingosine D-galactosyltransferase activity" EXACT [EC:2.4.1.47] +synonym: "UDPgalactose:N-acylsphingosine D-galactosyltransferase activity" EXACT [EC:2.4.1.47] +synonym: "uridine diphosphogalactose-acylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.47] +xref: EC:2.4.1.47 +xref: MetaCyc:2.4.1.47-RXN +xref: Reactome:R-HSA-6785933 "UGT8 transfers Gal from UDP-Gal to CERA" +xref: RHEA:13093 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047264 +name: heteroglycan alpha-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48] +synonym: "GDP mannose alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "heteropolysaccharide alpha-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.48 +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0047265 +name: poly(glycerol-phosphate) alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP." [EC:2.4.1.52, MetaCyc:2.4.1.52-RXN] +synonym: "UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity" EXACT [EC:2.4.1.52] +synonym: "UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.52] +synonym: "UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.52] +synonym: "uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity" EXACT [EC:2.4.1.52] +xref: EC:2.4.1.52 +xref: MetaCyc:2.4.1.52-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047266 +name: poly(ribitol-phosphate) beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP." [EC:2.4.1.53, MetaCyc:2.4.1.53-RXN] +synonym: "UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity" EXACT [EC:2.4.1.53] +synonym: "UDP-D-glucose polyribitol phosphate glucosyl transferase activity" EXACT [EC:2.4.1.53] +synonym: "UDP-D-glucose:polyribitol phosphate glucosyl transferase activity" EXACT [EC:2.4.1.53] +synonym: "UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.53] +synonym: "UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.53] +synonym: "uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity" EXACT [EC:2.4.1.53] +xref: EC:2.4.1.53 +xref: MetaCyc:2.4.1.53-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047267 +name: undecaprenyl-phosphate mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol." [EC:2.4.1.54] +synonym: "GDP mannose-undecaprenyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.54] +synonym: "GDP-D-mannose:lipid phosphate transmannosylase activity" EXACT [EC:2.4.1.54] +synonym: "GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity" EXACT [EC:2.4.1.54] +synonym: "guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.54] +xref: EC:2.4.1.54 +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0047268 +name: galactinol-raffinose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol." [EC:2.4.1.67, MetaCyc:2.4.1.67-RXN] +synonym: "alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity" EXACT [EC:2.4.1.67] +synonym: "stachyose synthetase activity" EXACT [EC:2.4.1.67] +xref: EC:2.4.1.67 +xref: MetaCyc:2.4.1.67-RXN +xref: RHEA:20776 +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0047269 +name: poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP." [EC:2.4.1.70, MetaCyc:2.4.1.70-RXN] +synonym: "UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.70] +synonym: "UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.70] +synonym: "uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.70] +xref: EC:2.4.1.70 +xref: MetaCyc:2.4.1.70-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0047270 +name: lipopolysaccharide glucosyltransferase II activity +namespace: molecular_function +def: "Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP." [EC:2.4.1.73, GOC:mr, GOC:pr, MetaCyc:2.4.1.73-RXN] +synonym: "LPS glucosyltransferase II activity" EXACT [] +synonym: "UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.73] +synonym: "UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.73] +synonym: "uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.73] +xref: EC:2.4.1.73 +xref: MetaCyc:2.4.1.73-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity +relationship: part_of GO:0009103 ! lipopolysaccharide biosynthetic process + +[Term] +id: GO:0047271 +name: glycosaminoglycan galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP." [EC:2.4.1.74, MetaCyc:2.4.1.74-RXN] +synonym: "UDP-galactose:glycosaminoglycan D-galactosyltransferase activity" EXACT [EC:2.4.1.74] +synonym: "UDPgalactose:glycosaminoglycan D-galactosyltransferase activity" EXACT [EC:2.4.1.74] +synonym: "uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity" EXACT [EC:2.4.1.74] +xref: EC:2.4.1.74 +xref: MetaCyc:2.4.1.74-RXN +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047272 +name: phosphopolyprenol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP." [EC:2.4.1.78, MetaCyc:2.4.1.78-RXN] +synonym: "UDP-glucose:phosphopolyprenol D-glucosyltransferase activity" EXACT [EC:2.4.1.78] +synonym: "UDPglucose:phosphopolyprenol D-glucosyltransferase activity" EXACT [EC:2.4.1.78] +synonym: "UDPglucose:polyprenol monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.78] +synonym: "uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.78] +xref: EC:2.4.1.78 +xref: MetaCyc:2.4.1.78-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047273 +name: galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity +namespace: molecular_function +alt_id: GO:0047226 +def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide." [EC:2.4.1.79, MetaCyc:2.4.1.79-RXN] +synonym: "beta-3GalNAc-T1 activity" EXACT [EC:2.4.1.79] +synonym: "beta3GalNAc-T1" RELATED [EC:2.4.1.79] +synonym: "galactosylgalactosylglucosylceramide beta-D- activity" EXACT [EC:2.4.1.79] +synonym: "globoside synthase activity" EXACT [EC:2.4.1.79] +synonym: "globoside synthetase activity" EXACT [EC:2.4.1.79] +synonym: "globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] +synonym: "globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity" EXACT [] +synonym: "UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.79] +synonym: "UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.79] +synonym: "UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] +synonym: "UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] +synonym: "uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] +xref: EC:2.4.1.79 +xref: MetaCyc:2.4.1.79-RXN +xref: Reactome:R-HSA-8878914 "B3GALNT1 transfer GalNAc to Gb3Cer to form Gb4Cer" +xref: RHEA:22252 +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0047274 +name: galactinol-sucrose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol." [EC:2.4.1.82, MetaCyc:2.4.1.82-RXN] +synonym: "1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.82] +synonym: "alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.82] +synonym: "galactinol:sucrose 6-galactosyl transferase activity" EXACT [] +synonym: "galactosyltransferase, galactinol-sucrose" EXACT [] +synonym: "raffinose synthase activity" EXACT [] +xref: EC:2.4.1.82 +xref: MetaCyc:2.4.1.82-RXN +xref: RHEA:20161 +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0047275 +name: glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.86, MetaCyc:2.4.1.86-RXN] +synonym: "GalT-4" RELATED [EC:2.4.1.86] +synonym: "paragloboside synthase activity" EXACT [EC:2.4.1.86] +synonym: "UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.86] +synonym: "UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.86] +synonym: "uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.86] +xref: EC:2.4.1.86 +xref: MetaCyc:2.4.1.86-RXN +xref: RHEA:16045 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047276 +name: N-acetyllactosaminide 3-alpha-galactosyltransferase activity +namespace: molecular_function +alt_id: GO:0003946 +def: "Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP." [EC:2.4.1.87, MetaCyc:2.4.1.87-RXN, RHEA:13013] +synonym: "alpha-galactosyltransferase activity" RELATED [EC:2.4.1.87] +synonym: "beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [] +synonym: "glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "N-acetyllactosaminide alpha-1,3-galactosyltransferase activity" EXACT [] +synonym: "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.87] +synonym: "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.87] +xref: EC:2.4.1.87 +xref: MetaCyc:2.4.1.151-RXN +xref: RHEA:13013 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047277 +name: globoside alpha-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.88, MetaCyc:2.4.1.88-RXN] +synonym: "Forssman synthase activity" RELATED [EC:2.4.1.88] +synonym: "forssman synthase activity" EXACT [EC:2.4.1.88] +synonym: "globoside acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.88] +synonym: "UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.88] +synonym: "uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.88] +xref: EC:2.4.1.88 +xref: MetaCyc:2.4.1.88-RXN +xref: RHEA:22164 +is_a: GO:0008376 ! acetylgalactosaminyltransferase activity + +[Term] +id: GO:0047278 +name: bilirubin-glucuronoside glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside." [RHEA:16885] +synonym: "bilirubin glucuronoside glucuronosyltransferase activity" EXACT [] +synonym: "bilirubin monoglucuronide transglucuronidase activity" EXACT [] +synonym: "bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity" EXACT [] +xref: KEGG_REACTION:R00062 +xref: MetaCyc:2.4.1.95-RXN +xref: RHEA:16885 +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0047279 +name: sn-glycerol-3-phosphate 1-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP." [EC:2.4.1.96, RHEA:20341] +synonym: "glycerol 3-phosphate 1alpha-galactosyltransferase activity" EXACT [EC:2.4.1.96] +synonym: "isofloridoside-phosphate synthase activity" EXACT [EC:2.4.1.96] +synonym: "UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity" EXACT [EC:2.4.1.96] +synonym: "UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] +synonym: "UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] +synonym: "UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] +synonym: "uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity" EXACT [EC:2.4.1.96] +xref: EC:2.4.1.96 +xref: KEGG_REACTION:R00854 +xref: MetaCyc:2.4.1.96-RXN +xref: RHEA:20341 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047280 +name: nicotinamide phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide." [EC:2.4.2.12, RHEA:16149] +synonym: "nicotinamide mononucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.12] +synonym: "nicotinamide mononucleotide synthetase activity" EXACT [EC:2.4.2.12] +synonym: "nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.12] +synonym: "NMN diphosphorylase activity" EXACT [EC:2.4.2.12] +synonym: "NMN pyrophosphorylase activity" EXACT [EC:2.4.2.12] +synonym: "NMN synthetase activity" EXACT [EC:2.4.2.12] +xref: EC:2.4.2.12 +xref: KEGG_REACTION:R01271 +xref: MetaCyc:2.4.2.12-RXN +xref: Reactome:R-HSA-197250 "NAMPT transfers PRIB to NAM to form NAMN" +xref: RHEA:16149 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047281 +name: dioxotetrahydropyrimidine phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine." [EC:2.4.2.20, MetaCyc:2.4.2.20-RXN] +synonym: "2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.20] +synonym: "dioxotetrahydropyrimidine phosphoribosyl transferase activity" EXACT [EC:2.4.2.20] +synonym: "dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.20] +synonym: "dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity" EXACT [EC:2.4.2.20] +synonym: "dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.20] +xref: EC:2.4.2.20 +xref: MetaCyc:2.4.2.20-RXN +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047282 +name: dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+)." [EC:2.4.2.27, RHEA:24392] +synonym: "dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] +synonym: "dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] +synonym: "thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] +xref: EC:2.4.2.27 +xref: KEGG_REACTION:R04222 +xref: MetaCyc:2.4.2.27-RXN +xref: RHEA:24392 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047283 +name: dolichyl-phosphate D-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP." [EC:2.4.2.32, MetaCyc:2.4.2.32-RXN] +synonym: "UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity" EXACT [EC:2.4.2.32] +xref: EC:2.4.2.32 +xref: MetaCyc:2.4.2.32-RXN +xref: RHEA:15361 +is_a: GO:0035252 ! UDP-xylosyltransferase activity + +[Term] +id: GO:0047284 +name: dolichyl-xylosyl-phosphate-protein xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein." [EC:2.4.2.33, MetaCyc:2.4.2.33-RXN] +synonym: "dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity" EXACT [EC:2.4.2.33] +xref: EC:2.4.2.33 +xref: MetaCyc:2.4.2.33-RXN +is_a: GO:0042285 ! xylosyltransferase activity + +[Term] +id: GO:0047285 +name: flavonol-3-O-glycoside xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP." [EC:2.4.2.35, MetaCyc:2.4.2.35-RXN] +synonym: "UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.35] +xref: EC:2.4.2.35 +xref: MetaCyc:2.4.2.35-RXN +xref: RHEA:19701 +is_a: GO:0035252 ! UDP-xylosyltransferase activity + +[Term] +id: GO:0047286 +name: NAD+-diphthamide ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide." [EC:2.4.2.36] +synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.36] +synonym: "mono(ADP-ribosyl)transferase activity" BROAD [EC:2.4.2.36] +synonym: "NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity" EXACT [EC:2.4.2.36] +synonym: "NAD-diphthamide ADP-ribosyltransferase activity" EXACT [] +xref: EC:2.4.2.36 +xref: MetaCyc:RXN-11372 +xref: Reactome:R-HSA-5336421 "DT fragment A ADP-ribosylates target cell EEF" +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047287 +name: lactosylceramide alpha-2,6-N-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP." [EC:2.4.99.11, MetaCyc:2.4.99.11-RXN] +synonym: "CMP-acetylneuraminate-lactosylceramide-sialyltransferase" BROAD [EC:2.4.99.11] +synonym: "CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.11] +synonym: "CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.11] +synonym: "CMP-sialic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.11] +synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase" BROAD [EC:2.4.99.11] +xref: EC:2.4.99.11 +xref: MetaCyc:2.4.99.11-RXN +xref: RHEA:21552 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0047288 +name: monosialoganglioside sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP." [EC:2.4.99.2, MetaCyc:2.4.99.2-RXN] +synonym: "CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.2] +xref: EC:2.4.99.2 +xref: MetaCyc:2.4.99.2-RXN +xref: RHEA:18021 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0047289 +name: galactosyldiacylglycerol alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)." [EC:2.4.99.5, RHEA:11664] +synonym: "CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.5] +xref: EC:2.4.99.5 +xref: KEGG_REACTION:R03468 +xref: MetaCyc:2.4.99.5-RXN +xref: RHEA:11664 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0047290 +name: (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP." [EC:2.4.99.7, RHEA:53896] +synonym: "(alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] +synonym: "(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity" EXACT [] +synonym: "alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] +synonym: "CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity" EXACT [EC:2.4.99.7] +synonym: "cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] +synonym: "NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] +synonym: "sialyltransferase 3C activity" RELATED [EC:2.4.99.7] +synonym: "sialyltransferase 7D activity" RELATED [EC:2.4.99.7] +synonym: "SIAT7" RELATED [EC:2.4.99.7] +synonym: "ST6GALNAC activity" EXACT [EC:2.4.99.7] +xref: EC:2.4.99.7 +xref: KEGG_REACTION:R04635 +xref: MetaCyc:2.4.99.7-RXN +xref: Reactome:R-HSA-981809 "ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen" +xref: RHEA:53896 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0047291 +name: lactosylceramide alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3." [EC:2.4.99.9, MetaCyc:2.4.99.9-RXN] +synonym: "CMP-acetylneuraminate-lactosylceramide-sialyltransferase" BROAD [EC:2.4.99.9] +synonym: "CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.9] +synonym: "CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.9] +synonym: "CMP-sialic acid:lactosylceramide-sialyltransferase activity" EXACT [EC:2.4.99.9] +synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity" EXACT [EC:2.4.99.9] +synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase" BROAD [EC:2.4.99.9] +synonym: "ganglioside GM3 synthase activity" EXACT [EC:2.4.99.9] +synonym: "ganglioside GM3 synthetase activity" EXACT [EC:2.4.99.9] +synonym: "GM3 synthase activity" EXACT [EC:2.4.99.9] +synonym: "GM3 synthetase activity" EXACT [EC:2.4.99.9] +synonym: "SAT 1" RELATED [EC:2.4.99.9] +xref: EC:2.4.99.9 +xref: MetaCyc:2.4.99.9-RXN +xref: RHEA:18417 +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0047292 +name: trihydroxypterocarpan dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate." [EC:2.5.1.36, MetaCyc:2.5.1.36-RXN] +synonym: "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity" EXACT [EC:2.5.1.36] +synonym: "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity" EXACT [EC:2.5.1.36] +synonym: "dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity" EXACT [EC:2.5.1.36] +synonym: "dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity" EXACT [EC:2.5.1.36] +xref: EC:2.5.1.36 +xref: MetaCyc:2.5.1.36-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047293 +name: 4-hydroxybenzoate nonaprenyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate." [EC:2.5.1.39, MetaCyc:2.5.1.39-RXN] +synonym: "4-hydroxybenzoate transferase activity" EXACT [EC:2.5.1.39] +synonym: "nonaprenyl-4-hydroxybenzoate transferase activity" EXACT [EC:2.5.1.39] +synonym: "p-hydroxybenzoate dimethylallyltransferase activity" EXACT [EC:2.5.1.39] +synonym: "p-hydroxybenzoate polyprenyltransferase activity" EXACT [EC:2.5.1.39] +synonym: "p-hydroxybenzoic acid-polyprenyl transferase activity" EXACT [EC:2.5.1.39] +synonym: "p-hydroxybenzoic-polyprenyl transferase activity" EXACT [EC:2.5.1.39] +synonym: "solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity" EXACT [EC:2.5.1.39] +xref: EC:2.5.1.39 +xref: MetaCyc:2.5.1.39-RXN +is_a: GO:0002094 ! polyprenyltransferase activity + +[Term] +id: GO:0047294 +name: phosphoglycerol geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate." [EC:2.5.1.41, RHEA:23404] +synonym: "geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.41] +synonym: "geranylgeranyl-transferase activity" EXACT [EC:2.5.1.41] +synonym: "glycerol phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.41] +xref: EC:2.5.1.41 +xref: KEGG_REACTION:R04158 +xref: MetaCyc:2.5.1.41-RXN +xref: RHEA:23404 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047295 +name: geranylgeranylglycerol-phosphate geranylgeranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate." [EC:2.5.1.42, RHEA:18109] +synonym: "geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.42] +synonym: "geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.42] +synonym: "geranylgeranyltransferase II" RELATED [EC:2.5.1.42] +xref: EC:2.5.1.42 +xref: KEGG_REACTION:R04520 +xref: MetaCyc:2.5.1.42-RXN +xref: RHEA:18109 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047296 +name: homospermidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine." [EC:2.5.1.44, MetaCyc:2.5.1.44-RXN] +synonym: "putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)" EXACT [EC:2.5.1.44] +xref: EC:2.5.1.44 +xref: MetaCyc:2.5.1.44-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047297 +name: asparagine-oxo-acid transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate." [EC:2.6.1.14, MetaCyc:2.6.1.14-RXN] +synonym: "asparagine--oxo-acid aminotransferase activity" EXACT [EC:2.6.1.14] +synonym: "asparagine-keto acid aminotransferase activity" EXACT [EC:2.6.1.14] +synonym: "asparagine-oxo-acid aminotransferase activity" EXACT [] +synonym: "L-asparagine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.14] +xref: EC:2.6.1.14 +xref: MetaCyc:2.6.1.14-RXN +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047298 +name: (S)-3-amino-2-methylpropionate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate." [EC:2.6.1.22, RHEA:13993] +synonym: "(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.22] +synonym: "(S)-3-amino-2-methylpropionate aminotransferase activity" EXACT [] +synonym: "beta-aminobutyric transaminase activity" EXACT [EC:2.6.1.22] +synonym: "beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.22] +synonym: "L-3-aminoisobutyrate aminotransferase activity" EXACT [EC:2.6.1.22] +synonym: "L-3-aminoisobutyrate transaminase activity" EXACT [EC:2.6.1.22] +synonym: "L-3-aminoisobutyric aminotransferase activity" EXACT [EC:2.6.1.22] +synonym: "L-AIBAT activity" EXACT [EC:2.6.1.22] +xref: EC:2.6.1.22 +xref: KEGG_REACTION:R04188 +xref: MetaCyc:2.6.1.22-RXN +xref: RHEA:13993 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047299 +name: tryptophan-phenylpyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine." [EC:2.6.1.28, RHEA:13741] +synonym: "L-tryptophan-alpha-ketoisocaproate aminotransferase activity" EXACT [EC:2.6.1.28] +synonym: "L-tryptophan:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.28] +synonym: "tryptophan--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.28] +synonym: "tryptophan-phenylpyruvate aminotransferase activity" EXACT [] +xref: EC:2.6.1.28 +xref: KEGG_REACTION:R01376 +xref: MetaCyc:2.6.1.28-RXN +xref: RHEA:13741 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047300 +name: pyridoxamine-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal." [EC:2.6.1.30, RHEA:12841] +synonym: "pyridoxamine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.30] +synonym: "pyridoxamine-pyruvate aminotransferase activity" EXACT [] +synonym: "pyridoxamine-pyruvic transaminase" BROAD [EC:2.6.1.30] +synonym: "pyridoxamine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.30] +synonym: "pyridoxamineu-pyruvic transaminase activity" EXACT [EC:2.6.1.30] +xref: EC:2.6.1.30 +xref: KEGG_REACTION:R01712 +xref: MetaCyc:2.6.1.30-RXN +xref: RHEA:12841 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047301 +name: valine-3-methyl-2-oxovalerate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine." [EC:2.6.1.32, RHEA:11468] +synonym: "L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity" EXACT [EC:2.6.1.32] +synonym: "valine--3-methyl-2-oxovalerate aminotransferase activity" EXACT [EC:2.6.1.32] +synonym: "valine--isoleucine aminotransferase activity" EXACT [EC:2.6.1.32] +synonym: "valine--isoleucine transaminase activity" EXACT [EC:2.6.1.32] +synonym: "valine-2-keto-methylvalerate aminotransferase activity" EXACT [EC:2.6.1.32] +synonym: "valine-3-methyl-2-oxovalerate aminotransferase activity" EXACT [] +xref: EC:2.6.1.32 +xref: KEGG_REACTION:R02200 +xref: MetaCyc:2.6.1.32-RXN +xref: RHEA:11468 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047302 +name: UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose." [EC:2.6.1.34, RHEA:18713] +synonym: "UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.34] +synonym: "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity" EXACT [] +synonym: "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity" EXACT [] +synonym: "uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity" EXACT [EC:2.6.1.34] +xref: EC:2.6.1.34 +xref: KEGG_REACTION:R04529 +xref: MetaCyc:2.6.1.34-RXN +xref: RHEA:18713 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047303 +name: glycine-oxaloacetate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate." [EC:2.6.1.35, RHEA:17141] +synonym: "glycine--oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.35] +synonym: "glycine-oxalacetate aminotransferase activity" EXACT [EC:2.6.1.35] +synonym: "glycine-oxaloacetate aminotransferase activity" EXACT [] +synonym: "glycine:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.35] +xref: EC:2.6.1.35 +xref: KEGG_REACTION:R00373 +xref: MetaCyc:2.6.1.35-RXN +xref: RHEA:17141 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047304 +name: 2-aminoethylphosphonate-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde." [EC:2.6.1.37, RHEA:17021] +synonym: "(2-aminoethyl)phosphonate aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "(2-aminoethyl)phosphonate transaminase activity" EXACT [EC:2.6.1.37] +synonym: "(2-aminoethyl)phosphonate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "(2-aminoethyl)phosphonate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "(2-aminoethyl)phosphonic acid aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "2-aminoethylphosphonate aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "2-aminoethylphosphonate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] +synonym: "2-aminoethylphosphonate-pyruvate aminotransferase activity" EXACT [] +xref: EC:2.6.1.37 +xref: KEGG_REACTION:R04152 +xref: MetaCyc:2.6.1.37-RXN +xref: RHEA:17021 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047305 +name: (R)-3-amino-2-methylpropionate-pyruvate transaminase activity +namespace: molecular_function +alt_id: GO:0047314 +def: "Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine." [EC:2.6.1.40, RHEA:18393] +comment: Note that this function was EC:2.6.1.61. +synonym: "(R)-3-amino-2-methylpropanoate aminotransferase activity" EXACT [] +synonym: "(R)-3-amino-2-methylpropanoate transaminase activity" EXACT [] +synonym: "(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] +synonym: "(R)-3-amino-2-methylpropionate transaminase activity" EXACT [] +synonym: "(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] +synonym: "(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity" EXACT [] +synonym: "beta-aminoisobutyrate--pyruvate transaminase activity" EXACT [EC:2.6.1.40] +synonym: "beta-aminoisobutyrate-pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] +synonym: "D-3-aminoisobutyrate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] +synonym: "D-3-aminoisobutyrate--pyruvate transaminase activity" EXACT [EC:2.6.1.40] +synonym: "D-3-aminoisobutyrate-pyruvate transaminase activity" EXACT [EC:2.6.1.40] +synonym: "D-AIBAT activity" EXACT [EC:2.6.1.40] +synonym: "D-beta-aminoisobutyrate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] +xref: EC:2.6.1.40 +xref: KEGG_REACTION:R02050 +xref: MetaCyc:2.6.1.40-RXN +xref: Reactome:R-HSA-909780 "(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine" +xref: RHEA:18393 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047306 +name: D-methionine-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine." [EC:2.6.1.41, RHEA:23836] +synonym: "D-methionine aminotransferase activity" EXACT [EC:2.6.1.41] +synonym: "D-methionine transaminase activity" EXACT [EC:2.6.1.41] +synonym: "D-methionine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.41] +synonym: "D-methionine-pyruvate aminotransferase activity" EXACT [] +synonym: "D-methionine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.41] +xref: EC:2.6.1.41 +xref: KEGG_REACTION:R03001 +xref: MetaCyc:2.6.1.41-RXN +xref: RHEA:23836 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047307 +name: diaminobutyrate-pyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde." [EC:2.6.1.46, RHEA:12380] +synonym: "diaminobutyrate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.46] +synonym: "diaminobutyrate-pyruvate aminotransferase activity" EXACT [] +synonym: "L-2,4-diaminobutanoate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.46] +synonym: "L-diaminobutyric acid transaminase activity" EXACT [EC:2.6.1.46] +xref: EC:2.6.1.46 +xref: KEGG_REACTION:R02293 +xref: MetaCyc:2.6.1.46-RXN +xref: RHEA:12380 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047308 +name: alanine-oxomalonate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate." [EC:2.6.1.47, RHEA:18809] +synonym: "alanine--oxomalonate aminotransferase activity" EXACT [EC:2.6.1.47] +synonym: "alanine-ketomalonate (mesoxalate) transaminase activity" EXACT [EC:2.6.1.47] +synonym: "alanine-oxomalonate aminotransferase activity" EXACT [] +synonym: "L-alanine-ketomalonate transaminase activity" EXACT [EC:2.6.1.47] +synonym: "L-alanine:oxomalonate aminotransferase activity" EXACT [EC:2.6.1.47] +xref: EC:2.6.1.47 +xref: KEGG_REACTION:R02970 +xref: MetaCyc:2.6.1.47-RXN +xref: RHEA:18809 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047309 +name: dihydroxyphenylalanine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate." [EC:2.6.1.49, RHEA:15273] +synonym: "3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.49] +synonym: "aspartate-DOPP transaminase (ADT)" EXACT [EC:2.6.1.49] +synonym: "dihydroxyphenylalanine aminotransferase activity" EXACT [] +synonym: "DOPA aminotransferase activity" EXACT [EC:2.6.1.49] +synonym: "dopa transaminase activity" EXACT [EC:2.6.1.49] +synonym: "glutamate-DOPP transaminase (GDT)" EXACT [EC:2.6.1.49] +synonym: "L-dopa transaminase activity" EXACT [EC:2.6.1.49] +synonym: "phenylalanine-DOPP transaminase (PDT)" EXACT [EC:2.6.1.49] +xref: EC:2.6.1.49 +xref: KEGG_REACTION:R02077 +xref: MetaCyc:2.6.1.49-RXN +xref: RHEA:15273 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047310 +name: glutamine-scyllo-inositol transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate." [EC:2.6.1.50, RHEA:22920] +synonym: "glutamine scyllo-inosose aminotransferase activity" EXACT [EC:2.6.1.50] +synonym: "glutamine--scyllo-inosose aminotransferase activity" EXACT [EC:2.6.1.50] +synonym: "glutamine--scyllo-inosose transaminase activity" EXACT [EC:2.6.1.50] +synonym: "glutamine-scyllo-inosose aminotransferase activity" EXACT [] +synonym: "glutamine-scyllo-inosose transaminase activity" EXACT [] +synonym: "L-glutamine-keto-scyllo-inositol aminotransferase activity" EXACT [EC:2.6.1.50] +synonym: "L-glutamine-scyllo-inosose transaminase activity" EXACT [EC:2.6.1.50] +synonym: "L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity" EXACT [EC:2.6.1.50] +xref: EC:2.6.1.50 +xref: KEGG_REACTION:R02781 +xref: MetaCyc:2.6.1.50-RXN +xref: RHEA:22920 +is_a: GO:0070548 ! L-glutamine aminotransferase activity + +[Term] +id: GO:0047311 +name: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine." [EC:2.6.1.56, RHEA:15497] +synonym: "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity" EXACT [] +synonym: "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity" EXACT [EC:2.6.1.56] +synonym: "guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity" EXACT [EC:2.6.1.56] +synonym: "L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity" EXACT [EC:2.6.1.56] +xref: EC:2.6.1.56 +xref: KEGG_REACTION:R03502 +xref: MetaCyc:2.6.1.56-RXN +xref: RHEA:15497 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047312 +name: L-phenylalanine:pyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine." [EC:2.6.1.58, MetaCyc:2.6.1.58-RXN] +synonym: "histidine aminotransferase activity" RELATED [GOC:kad] +synonym: "histidine:pyruvate aminotransferase activity" RELATED [EC:2.6.1.58, GOC:kad] +synonym: "L-histidine:pyruvate aminotransferase activity" RELATED [GOC:kad] +synonym: "L-phenylalanine(L-histidine):pyruvate aminotransferase activity" BROAD [EC:2.6.1.58] +synonym: "L-phenylalanine:pyruvate transaminase activity" EXACT [GOC:kad] +synonym: "phenylalanine (histidine) aminotransferase activity" BROAD [EC:2.6.1.58] +synonym: "phenylalanine(histidine) aminotransferase activity" BROAD [] +synonym: "phenylalanine(histidine) transaminase activity" BROAD [EC:2.6.1.58] +synonym: "phenylalanine(histidine):pyruvate aminotransferase activity" BROAD [EC:2.6.1.58] +xref: EC:2.6.1.58 +xref: KEGG_REACTION:R00692 +xref: MetaCyc:2.6.1.58-RXN +xref: Reactome:R-HSA-893593 "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine" +is_a: GO:0070546 ! L-phenylalanine aminotransferase activity + +[Term] +id: GO:0047313 +name: aromatic-amino-acid-glyoxylate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid." [EC:2.6.1.60, MetaCyc:2.6.1.60-RXN] +synonym: "aromatic-amino-acid--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.60] +synonym: "aromatic-amino-acid-glyoxylate aminotransferase activity" EXACT [] +synonym: "aromatic-amino-acid:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.60] +xref: EC:2.6.1.60 +xref: MetaCyc:2.6.1.60-RXN +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047315 +name: kynurenine-glyoxylate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine." [EC:2.6.1.63, RHEA:19249] +synonym: "kynurenine--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.63] +synonym: "kynurenine-glyoxylate aminotransferase activity" EXACT [] +synonym: "L-kynurenine:glyoxylate aminotransferase (cyclizing)" EXACT [EC:2.6.1.63] +xref: EC:2.6.1.63 +xref: KEGG_REACTION:R01957 +xref: MetaCyc:2.6.1.63-RXN +xref: RHEA:19249 +is_a: GO:0036137 ! kynurenine aminotransferase activity + +[Term] +id: GO:0047316 +name: glutamine-phenylpyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine." [EC:2.6.1.64, RHEA:17593] +synonym: "glutamine transaminase K activity" RELATED [EC:2.6.1.64] +synonym: "glutamine--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.64] +synonym: "glutamine-phenylpyruvate aminotransferase activity" EXACT [] +synonym: "L-glutamine:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.64] +xref: EC:2.6.1.64 +xref: KEGG_REACTION:R01375 +xref: MetaCyc:2.6.1.64-RXN +xref: RHEA:17593 +is_a: GO:0070548 ! L-glutamine aminotransferase activity + +[Term] +id: GO:0047317 +name: N6-acetyl-beta-lysine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate." [EC:2.6.1.65, MetaCyc:2.6.1.65-RXN] +synonym: "6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.65] +synonym: "epsilon-acetyl-beta-lysine aminotransferase activity" EXACT [EC:2.6.1.65] +synonym: "N(6)-acetyl-beta-lysine aminotransferase activity" EXACT [EC:2.6.1.65] +synonym: "N6-acetyl-beta-lysine aminotransferase activity" EXACT [] +xref: EC:2.6.1.65 +xref: MetaCyc:2.6.1.65-RXN +xref: RHEA:16889 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047319 +name: aspartate-phenylpyruvate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate." [EC:2.6.1.70, RHEA:14097] +synonym: "aspartate--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.70] +synonym: "aspartate-phenylpyruvate aminotransferase activity" EXACT [] +synonym: "L-aspartate:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.70] +xref: EC:2.6.1.70 +xref: KEGG_REACTION:R00695 +xref: MetaCyc:2.6.1.70-RXN +xref: RHEA:14097 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047320 +name: D-4-hydroxyphenylglycine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate." [EC:2.6.1.72, RHEA:15589] +synonym: "D-4-hydroxyphenylglycine aminotransferase activity" EXACT [] +synonym: "D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.72] +synonym: "D-hydroxyphenylglycine aminotransferase activity" EXACT [EC:2.6.1.72] +xref: EC:2.6.1.72 +xref: KEGG_REACTION:R04234 +xref: MetaCyc:2.6.1.72-RXN +xref: RHEA:15589 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047321 +name: diphosphate-protein phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein." [EC:2.7.99.1, MetaCyc:2.7.99.1-RXN] +synonym: "diphosphate:microsomal-membrane-protein O-phosphotransferase activity" BROAD [EC:2.7.99.1] +synonym: "DiPPT" RELATED [EC:2.7.99.1] +synonym: "pyrophosphate-protein phosphotransferase activity" EXACT [EC:2.7.99.1] +synonym: "pyrophosphate:protein phosphotransferase activity" EXACT [EC:2.7.99.1] +synonym: "triphosphate-protein phosphotransferase activity" EXACT [EC:2.7.99.1] +synonym: "triphosphate:microsomal-membrane-protein phosphotransferase activity" EXACT [EC:2.7.99.1] +xref: EC:2.7.99.1 +xref: MetaCyc:2.7.99.1-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047322 +name: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP." [EC:2.7.11.31, MetaCyc:2.7.1.109-RXN] +synonym: "3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "3-hydroxy-3-methylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "AMPK" RELATED [EC:2.7.11.31] +synonym: "ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity" EXACT [EC:2.7.11.31] +synonym: "beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "HMG-CoA reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity" EXACT [EC:2.7.11.31] +synonym: "hydroxymethylglutaryl coenzyme A reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity" EXACT [EC:2.7.11.31] +synonym: "hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity" EXACT [EC:2.7.11.31] +synonym: "hydroxymethylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] +synonym: "reductase kinase activity" BROAD [EC:2.7.11.31] +synonym: "STK29" RELATED [EC:2.7.11.31] +xref: EC:2.7.11.31 +xref: MetaCyc:2.7.1.109-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0047323 +name: [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate." [EC:2.7.11.4] +synonym: "3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity" EXACT [EC:2.7.11.4] +synonym: "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity" EXACT [] +synonym: "ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity" EXACT [EC:2.7.11.4] +synonym: "BCK" RELATED [EC:2.7.11.4] +synonym: "BCKD kinase activity" EXACT [EC:2.7.11.4] +synonym: "BCODH kinase activity" EXACT [EC:2.7.11.4] +synonym: "branched-chain 2-oxo acid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] +synonym: "branched-chain alpha-ketoacid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] +synonym: "branched-chain keto acid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] +synonym: "branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.4] +synonym: "STK2" RELATED [EC:2.7.11.4] +xref: EC:2.7.11.4 +xref: MetaCyc:2.7.11.4-RXN +xref: Reactome:R-HSA-5693148 "BCKDK phosphorylates BCKDH" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0047324 +name: phosphoenolpyruvate-glycerone phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate." [EC:2.7.1.121, RHEA:18381] +synonym: "phosphoenolpyruvate:glycerone phosphotransferase activity" EXACT [EC:2.7.1.121] +xref: EC:2.7.1.121 +xref: KEGG_REACTION:R01012 +xref: MetaCyc:2.7.1.121-RXN +xref: RHEA:18381 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047325 +name: inositol tetrakisphosphate 1-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [EC:2.7.1.134, MetaCyc:2.7.1.134-RXN] +synonym: "1D-myo-inositol-tetrakisphosphate 1-kinase activity" EXACT [EC:2.7.1.134] +synonym: "1D-myo-inositol-trisphosphate 5-kinase activity" RELATED [EC:2.7.1.134] +synonym: "1D-myo-inositol-trisphosphate 6-kinase activity" RELATED [EC:2.7.1.134] +synonym: "ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.134] +synonym: "inositol 3,4,5,6-tetrakisphosphate 1-kinase activity" EXACT [] +synonym: "inositol-tetrakisphosphate 1-kinase activity" BROAD [] +synonym: "inositol-trisphosphate 5-kinase activity" RELATED [EC:2.7.1.134] +synonym: "inositol-trisphosphate 6-kinase activity" RELATED [EC:2.7.1.134] +xref: EC:2.7.1.134 +xref: MetaCyc:2.7.1.134-RXN +xref: Reactome:R-HSA-1855162 "I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol" +xref: Reactome:R-HSA-994137 "ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5" +xref: RHEA:12452 +is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity + +[Term] +id: GO:0047326 +name: inositol tetrakisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [EC:2.7.1.140, MetaCyc:2.7.1.140-RXN] +synonym: "1D-myo-inositol-tetrakisphosphate 5-kinase activity" EXACT [] +synonym: "ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.140] +synonym: "inositol 1,3,4,6-tetrakisphosphate 5-kinase activity" EXACT [] +synonym: "inositol-tetrakisphosphate 5-kinase activity" EXACT [] +xref: EC:2.7.1.140 +xref: MetaCyc:2.7.1.140-RXN +xref: Reactome:R-HSA-1855228 "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus" +xref: RHEA:12717 +is_a: GO:0051765 ! inositol tetrakisphosphate kinase activity + +[Term] +id: GO:0047327 +name: glycerol-3-phosphate-glucose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol." [EC:2.7.1.142, RHEA:21288] +synonym: "sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.142] +xref: EC:2.7.1.142 +xref: KEGG_REACTION:R00850 +xref: MetaCyc:2.7.1.142-RXN +xref: RHEA:21288 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047328 +name: acyl-phosphate-hexose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid." [EC:2.7.1.61, MetaCyc:2.7.1.61-RXN] +synonym: "acyl-phosphate:D-hexose phosphotransferase activity" EXACT [EC:2.7.1.61] +synonym: "hexose phosphate:hexose phosphotransferase activity" EXACT [EC:2.7.1.61] +xref: EC:2.7.1.61 +xref: MetaCyc:2.7.1.61-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047329 +name: phosphoramidate-hexose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3." [EC:2.7.1.62, MetaCyc:2.7.1.62-RXN] +synonym: "phosphoramidate-hexose transphosphorylase activity" EXACT [EC:2.7.1.62] +synonym: "phosphoramidate:hexose 1-phosphotransferase activity" EXACT [EC:2.7.1.62] +synonym: "phosphoramidic-hexose transphosphorylase activity" EXACT [EC:2.7.1.62] +xref: EC:2.7.1.62 +xref: MetaCyc:2.7.1.62-RXN +xref: RHEA:10972 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047330 +name: polyphosphate-glucose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate." [EC:2.7.1.63, MetaCyc:2.7.1.63-RXN] +synonym: "polyphosphate glucokinase activity" EXACT [EC:2.7.1.63] +synonym: "polyphosphate-D-(+)-glucose-6-phosphotransferase activity" EXACT [EC:2.7.1.63] +synonym: "polyphosphate-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.63] +synonym: "polyphosphate:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.63] +xref: EC:2.7.1.63 +xref: MetaCyc:2.7.1.63-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047331 +name: diphosphate-glycerol phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate." [EC:2.7.1.79, RHEA:13689] +synonym: "diphosphate:glycerol 1-phosphotransferase activity" EXACT [EC:2.7.1.79] +synonym: "PPi-glycerol phosphotransferase activity" EXACT [EC:2.7.1.79] +synonym: "pyrophosphate--glycerol phosphotransferase activity" EXACT [EC:2.7.1.79] +xref: EC:2.7.1.79 +xref: KEGG_REACTION:R01044 +xref: MetaCyc:2.7.1.79-RXN +xref: RHEA:13689 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047332 +name: diphosphate-serine phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate." [EC:2.7.1.80, RHEA:23764] +synonym: "diphosphate:L-serine O-phosphotransferase activity" EXACT [EC:2.7.1.80] +synonym: "pyrophosphate--serine phosphotransferase activity" EXACT [EC:2.7.1.80] +synonym: "pyrophosphate-L-serine phosphotransferase activity" EXACT [EC:2.7.1.80] +xref: EC:2.7.1.80 +xref: KEGG_REACTION:R00584 +xref: MetaCyc:2.7.1.80-RXN +xref: RHEA:23764 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047333 +name: dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+)." [EC:2.7.1.88, RHEA:16281] +synonym: "ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity" EXACT [EC:2.7.1.88] +synonym: "ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity" EXACT [EC:2.7.1.88] +synonym: "dihydrostreptomycin 6-phosphate kinase (phosphorylating)" EXACT [EC:2.7.1.88] +synonym: "dihydrostreptomycin-6-phosphate 3'alpha-kinase activity" EXACT [EC:2.7.1.88] +xref: EC:2.7.1.88 +xref: KEGG_REACTION:R03395 +xref: MetaCyc:2.7.1.88-RXN +xref: RHEA:16281 +is_a: GO:0034071 ! aminoglycoside phosphotransferase activity + +[Term] +id: GO:0047334 +name: diphosphate-fructose-6-phosphate 1-phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate." [EC:2.7.1.90, MetaCyc:2.7.1.90-RXN] +synonym: "6-phosphofructokinase (diphosphate) activity" EXACT [EC:2.7.1.90] +synonym: "6-phosphofructokinase (pyrophosphate) activity" EXACT [EC:2.7.1.90] +synonym: "diphosphate-dependent 6-phosphofructose-1-kinase activity" EXACT [EC:2.7.1.90] +synonym: "diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.90] +synonym: "inorganic pyrophosphate-dependent phosphofructokinase activity" EXACT [EC:2.7.1.90] +synonym: "inorganic pyrophosphate-phosphofructokinase activity" EXACT [EC:2.7.1.90] +synonym: "pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.90] +synonym: "pyrophosphate-dependent 6-phosphofructose-1-kinase activity" EXACT [EC:2.7.1.90] +synonym: "pyrophosphate-dependent phosphofructo-1-kinase activity" EXACT [EC:2.7.1.90] +synonym: "pyrophosphate-fructose 6-phosphate phosphotransferase activity" EXACT [EC:2.7.1.90] +xref: EC:2.7.1.90 +xref: MetaCyc:2.7.1.90-RXN +xref: RHEA:13613 +is_a: GO:0008443 ! phosphofructokinase activity + +[Term] +id: GO:0047335 +name: 3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate." [EC:2.7.4.17, MetaCyc:2.7.4.17-RXN] +synonym: "1,3-diphosphoglycerate-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] +synonym: "3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] +synonym: "diphosphoglycerate-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] +xref: EC:2.7.4.17 +xref: MetaCyc:2.7.4.17-RXN +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0047336 +name: 5-methyldeoxycytidine-5'-phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+)." [EC:2.7.4.19, RHEA:11396] +synonym: "ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity" EXACT [EC:2.7.4.19] +xref: EC:2.7.4.19 +xref: KEGG_REACTION:R04235 +xref: MetaCyc:2.7.4.19-RXN +xref: RHEA:11396 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0047337 +name: dolichyl-diphosphate-polyphosphate phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate." [EC:2.7.4.20, MetaCyc:2.7.4.20-RXN] +synonym: "dolichyl-diphosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.20] +synonym: "dolichylpyrophosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.20] +xref: EC:2.7.4.20 +xref: MetaCyc:2.7.4.20-RXN +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0047338 +name: UTP:xylose-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate." [EC:2.7.7.11, MetaCyc:2.7.7.11-RXN] +synonym: "UDP-xylose pyrophosphorylase activity" EXACT [EC:2.7.7.11] +synonym: "uridine diphosphoxylose pyrophosphorylase activity" EXACT [EC:2.7.7.11] +synonym: "uridylyltransferase, xylose 1-phosphate" EXACT [EC:2.7.7.11] +synonym: "UTP-xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] +synonym: "UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] +synonym: "xylose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] +synonym: "xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] +xref: EC:2.7.7.11 +xref: MetaCyc:2.7.7.11-RXN +xref: RHEA:18389 +is_a: GO:0051748 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity + +[Term] +id: GO:0047339 +name: nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity +namespace: molecular_function +alt_id: GO:0047340 +def: "Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate." [EC:2.7.7.28, MetaCyc:2.7.7.28-RXN] +synonym: "GDP hexose pyrophosphorylase activity" NARROW [EC:2.7.7.28] +synonym: "GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity" NARROW [EC:2.7.7.28] +synonym: "GTP:hexose-1-phosphate guanylyltransferase activity" NARROW [] +synonym: "guanosine diphosphohexose pyrophosphorylase activity" NARROW [EC:2.7.7.28] +synonym: "hexose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.28] +synonym: "hexose 1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] +synonym: "hexose nucleotidylating enzyme activity" EXACT [EC:2.7.7.28] +synonym: "hexose-1-phosphate guanylyltransferase activity" NARROW [] +synonym: "NDP hexose pyrophosphorylase activity" EXACT [EC:2.7.7.28] +synonym: "NDP-hexose diphosphorylase activity" EXACT [] +synonym: "NDP-hexose pyrophosphorylase activity" EXACT [] +synonym: "NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] +synonym: "NTP:hexose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] +synonym: "nucleoside diphosphohexose pyrophosphorylase activity" EXACT [EC:2.7.7.28] +synonym: "nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] +xref: EC:2.7.7.28 +xref: MetaCyc:2.7.7.28-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0047341 +name: fucose-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose." [EC:2.7.7.30, RHEA:13549] +synonym: "GDP fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] +synonym: "GDP-fucose diphosphorylase activity" EXACT [EC:2.7.7.30] +synonym: "GDP-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] +synonym: "GDP-L-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] +synonym: "GTP:beta-L-fucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.30] +synonym: "GTP:fucose-1-phosphate guanylyltransferase activity" EXACT [] +synonym: "GTP:L-fucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.30] +synonym: "guanosine diphosphate L-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] +xref: EC:2.7.7.30 +xref: KEGG_REACTION:R01951 +xref: MetaCyc:2.7.7.30-RXN +xref: Reactome:R-HSA-6787533 "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc" +xref: RHEA:13549 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0047342 +name: galactose-1-phosphate thymidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose." [EC:2.7.7.32, RHEA:17165] +synonym: "dTDP galactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] +synonym: "dTDP-galactose diphosphorylase activity" EXACT [EC:2.7.7.32] +synonym: "dTDP-galactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] +synonym: "dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.32] +synonym: "galactose 1-phosphate thymidylyl transferase activity" EXACT [EC:2.7.7.32] +synonym: "thymidine diphosphogalactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] +synonym: "thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.32] +xref: EC:2.7.7.32 +xref: KEGG_REACTION:R02329 +xref: MetaCyc:2.7.7.32-RXN +xref: RHEA:17165 +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0047343 +name: glucose-1-phosphate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate." [EC:2.7.7.33, RHEA:18213] +synonym: "CDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] +synonym: "CDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.33] +synonym: "CDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] +synonym: "CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.33] +synonym: "CTP:D-glucose-1-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.33] +synonym: "CTP:glucose-1-phosphate cytidylyltransferase activity" EXACT [] +synonym: "cytidine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] +synonym: "cytidine diphosphate-D-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] +synonym: "cytidine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] +xref: EC:2.7.7.33 +xref: KEGG_REACTION:R00956 +xref: MetaCyc:2.7.7.33-RXN +xref: RHEA:18213 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0047344 +name: glucose-1-phosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose." [EC:2.7.7.34, RHEA:10708] +synonym: "GDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] +synonym: "GDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.34] +synonym: "GDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] +synonym: "GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.34] +synonym: "GTP:glucose-1-phosphate guanylyltransferase activity" EXACT [] +synonym: "guanosine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] +xref: EC:2.7.7.34 +xref: KEGG_REACTION:R00954 +xref: MetaCyc:2.7.7.34-RXN +xref: RHEA:10708 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0047345 +name: ribose-5-phosphate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate." [EC:2.7.7.35, RHEA:14529] +synonym: "adenosine diphosphoribose phosphorylase activity" EXACT [EC:2.7.7.35] +synonym: "ADP ribose phosphorylase activity" EXACT [EC:2.7.7.35] +synonym: "ADP-ribose phosphorylase activity" EXACT [EC:2.7.7.35] +synonym: "ADP:D-ribose-5-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.35] +synonym: "ADP:ribose-5-phosphate adenylyltransferase activity" EXACT [] +xref: EC:2.7.7.35 +xref: KEGG_REACTION:R01052 +xref: MetaCyc:2.7.7.35-RXN +xref: RHEA:14529 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0047346 +name: aldose-1-phosphate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose." [EC:2.7.7.36, MetaCyc:2.7.7.36-RXN] +synonym: "adenosine diphosphate glucose:orthophosphate adenylyltransferase activity" EXACT [EC:2.7.7.36] +synonym: "adenosine diphosphosugar phosphorylase activity" EXACT [EC:2.7.7.36] +synonym: "ADP sugar phosphorylase activity" EXACT [EC:2.7.7.36] +synonym: "ADP-aldose phosphorylase activity" EXACT [EC:2.7.7.36] +synonym: "ADP-sugar phosphorylase activity" BROAD [EC:2.7.7.36] +synonym: "ADP:aldose-1-phosphate adenylyltransferase activity" EXACT [] +synonym: "ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.36] +synonym: "ADPaldose phosphorylase activity" EXACT [EC:2.7.7.36] +synonym: "sugar-1-phosphate adenylyltransferase activity" BROAD [EC:2.7.7.36] +xref: EC:2.7.7.36 +xref: MetaCyc:2.7.7.36-RXN +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0047347 +name: aldose-1-phosphate nucleotidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose." [EC:2.7.7.37, MetaCyc:2.7.7.37-RXN] +synonym: "glucose 1-phosphate inosityltransferase activity" EXACT [EC:2.7.7.37] +synonym: "NDP sugar phosphorylase activity" EXACT [EC:2.7.7.37] +synonym: "NDP-aldose phosphorylase activity" EXACT [EC:2.7.7.37] +synonym: "NDP-sugar phosphorylase activity" BROAD [EC:2.7.7.37] +synonym: "NDP:aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] +synonym: "NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] +synonym: "NDPaldose phosphorylase activity" EXACT [EC:2.7.7.37] +synonym: "nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] +synonym: "nucleoside diphosphosugar phosphorylase activity" EXACT [EC:2.7.7.37] +synonym: "sugar nucleotide phosphorylase activity" EXACT [EC:2.7.7.37] +synonym: "sugar phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] +synonym: "sugar-1-phosphate nucleotidyltransferase activity" BROAD [EC:2.7.7.37] +xref: EC:2.7.7.37 +xref: MetaCyc:2.7.7.37-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0047348 +name: glycerol-3-phosphate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate." [EC:2.7.7.39, RHEA:13361] +synonym: "CDP-glycerol diphosphorylase activity" EXACT [EC:2.7.7.39] +synonym: "CDP-glycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] +synonym: "CTP:glycerol 3-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.39] +synonym: "CTP:glycerol-3-phosphate cytidylyltransferase activity" EXACT [] +synonym: "CTP:sn-glycerol-3-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.39] +synonym: "cytidine diphosphate glycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] +synonym: "cytidine diphosphoglycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] +synonym: "Gro-PCT" RELATED [EC:2.7.7.39] +xref: EC:2.7.7.39 +xref: KEGG_REACTION:R00856 +xref: MetaCyc:2.7.7.39-RXN +xref: RHEA:13361 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0047349 +name: D-ribitol-5-phosphate cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate." [EC:2.7.7.40, RHEA:12456] +synonym: "CDP ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] +synonym: "CDP-ribitol diphosphorylase activity" EXACT [EC:2.7.7.40] +synonym: "CDP-ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] +synonym: "CTP:D-ribitol-5-phosphate cytidylyltransferase activity" EXACT [] +synonym: "cytidine diphosphate ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] +synonym: "cytidine diphosphoribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] +synonym: "ribitol 5-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.40] +xref: EC:2.7.7.40 +xref: KEGG_REACTION:R02921 +xref: MetaCyc:2.7.7.40-RXN +xref: RHEA:12456 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0047350 +name: glucuronate-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate." [EC:2.7.7.44, RHEA:16325] +synonym: "UDP-D-glucuronic acid pyrophosphorylase activity" EXACT [EC:2.7.7.44] +synonym: "UDP-glucuronate pyrophosphorylase activity" EXACT [EC:2.7.7.44] +synonym: "UDP-glucuronic acid pyrophosphorylase activity" EXACT [EC:2.7.7.44] +synonym: "uridine diphosphoglucuronic pyrophosphorylase activity" EXACT [EC:2.7.7.44] +synonym: "UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity" EXACT [EC:2.7.7.44] +synonym: "UTP:glucuronate-1-phosphate uridylyltransferase activity" EXACT [] +xref: EC:2.7.7.44 +xref: KEGG_REACTION:R01381 +xref: MetaCyc:2.7.7.44-RXN +xref: RHEA:16325 +is_a: GO:0070569 ! uridylyltransferase activity + +[Term] +id: GO:0047351 +name: guanosine-triphosphate guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+)." [EC:2.7.7.45, RHEA:18153] +synonym: "GTP:GTP guanylyltransferase activity" BROAD [] +xref: EC:2.7.7.45 +xref: KEGG_REACTION:R00012 +xref: MetaCyc:2.7.7.45-RXN +xref: RHEA:18153 +is_a: GO:0070568 ! guanylyltransferase activity + +[Term] +id: GO:0047352 +name: adenylylsulfate-ammonia adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate." [EC:2.7.7.51, RHEA:19197] +synonym: "adenylylsulfate:ammonia adenylyltransferase activity" EXACT [EC:2.7.7.51] +synonym: "adenylylsulphate-ammonia adenylyltransferase activity" EXACT [] +synonym: "APSAT" RELATED [EC:2.7.7.51] +xref: EC:2.7.7.51 +xref: KEGG_REACTION:R01619 +xref: MetaCyc:2.7.7.51-RXN +xref: RHEA:19197 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0047353 +name: N-methylphosphoethanolamine cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate." [EC:2.7.7.57, RHEA:10576] +synonym: "CTP:N-methylethanolamine-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.57] +synonym: "CTP:N-methylphosphoethanolamine cytidylyltransferase activity" EXACT [] +synonym: "CTP:P-MEA cytidylyltransferase activity" EXACT [EC:2.7.7.57] +synonym: "monomethylethanolamine phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.57] +xref: EC:2.7.7.57 +xref: KEGG_REACTION:R03375 +xref: MetaCyc:2.7.7.57-RXN +xref: RHEA:10576 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0047354 +name: sphingosine cholinephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine." [EC:2.7.8.10, RHEA:21224] +synonym: "CDP-choline-sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] +synonym: "CDP-choline:sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] +synonym: "cytidine diphosphocholine-sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] +synonym: "phosphorylcholine-sphingosine transferase activity" EXACT [EC:2.7.8.10] +synonym: "sphingosine choline phosphotransferase activity" EXACT [] +xref: EC:2.7.8.10 +xref: KEGG_REACTION:R01929 +xref: MetaCyc:2.7.8.10-RXN +xref: RHEA:21224 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047355 +name: CDP-glycerol glycerophosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP." [EC:2.7.8.12, MetaCyc:2.7.8.12-RXN] +synonym: "CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity" EXACT [EC:2.7.8.12] +synonym: "CDPglycerol glycerophosphotransferase activity" EXACT [EC:2.7.8.12] +synonym: "CGPTase activity" EXACT [EC:2.7.8.12] +synonym: "cytidine diphosphoglycerol glycerophosphotransferase activity" EXACT [EC:2.7.8.12] +synonym: "glycerophosphate synthetase activity" EXACT [EC:2.7.8.12] +synonym: "poly(glycerol phosphate) polymerase activity" EXACT [EC:2.7.8.12] +synonym: "teichoic acid glycerol transferase activity" EXACT [EC:2.7.8.12] +synonym: "teichoic-acid synthase activity" BROAD [EC:2.7.8.12] +xref: EC:2.7.8.12 +xref: MetaCyc:2.7.8.12-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047356 +name: CDP-ribitol ribitolphosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP." [EC:2.7.8.14, MetaCyc:2.7.8.14-RXN] +synonym: "CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity" EXACT [EC:2.7.8.14] +synonym: "CDPribitol ribitolphosphotransferase activity" EXACT [EC:2.7.8.14] +synonym: "poly(ribitol phosphate) synthetase activity" EXACT [EC:2.7.8.14] +synonym: "polyribitol phosphate polymerase activity" EXACT [EC:2.7.8.14] +synonym: "polyribitol phosphate synthetase activity" EXACT [EC:2.7.8.14] +synonym: "teichoate synthase activity" EXACT [EC:2.7.8.14] +synonym: "teichoate synthetase activity" EXACT [EC:2.7.8.14] +synonym: "teichoic-acid synthase activity" BROAD [EC:2.7.8.14] +xref: EC:2.7.8.14 +xref: MetaCyc:2.7.8.14-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047357 +name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP." [EC:2.7.8.18, RHEA:22440] +synonym: "galactose-1-phosphotransferase activity" EXACT [EC:2.7.8.18] +synonym: "galactosyl phosphotransferase activity" EXACT [EC:2.7.8.18] +synonym: "UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] +synonym: "UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] +synonym: "UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] +synonym: "uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity" EXACT [EC:2.7.8.18] +xref: EC:2.7.8.18 +xref: KEGG_REACTION:R00504 +xref: MetaCyc:2.7.8.18-RXN +xref: RHEA:22440 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047358 +name: UDP-glucose-glycoprotein glucose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP." [EC:2.7.8.19, MetaCyc:2.7.8.19-RXN] +synonym: "Glc-phosphotransferase activity" EXACT [EC:2.7.8.19] +synonym: "GlcPTase activity" EXACT [EC:2.7.8.19] +synonym: "UDP-glucose:glycoprotein glucose-1-phosphotransferase activity" EXACT [EC:2.7.8.19] +synonym: "UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity" EXACT [EC:2.7.8.19] +synonym: "UDPglucose-glycoprotein glucose phosphotransferase activity" EXACT [EC:2.7.8.19] +synonym: "UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity" EXACT [EC:2.7.8.19] +synonym: "uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity" EXACT [EC:2.7.8.19] +xref: EC:2.7.8.19 +xref: MetaCyc:2.7.8.19-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047359 +name: 1-alkenyl-2-acylglycerol choline phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP." [EC:2.7.8.22, MetaCyc:2.7.8.22-RXN] +synonym: "CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity" EXACT [EC:2.7.8.22] +synonym: "CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.22] +xref: EC:2.7.8.22 +xref: MetaCyc:2.7.8.22-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047360 +name: undecaprenyl-phosphate galactose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP." [EC:2.7.8.6, RHEA:11652] +synonym: "poly(isoprenol)-phosphate galactose phosphotransferase activity" EXACT [EC:2.7.8.6] +synonym: "poly(isoprenol)-phosphate galactosephosphotransferase activity" EXACT [EC:2.7.8.6] +synonym: "poly(isoprenyl)phosphate galactosephosphatetransferase activity" EXACT [EC:2.7.8.6] +synonym: "UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity" EXACT [EC:2.7.8.6] +synonym: "undecaprenyl phosphate galactosyl-1-phosphate transferase activity" EXACT [EC:2.7.8.6] +xref: EC:2.7.8.6 +xref: KEGG_REACTION:R01535 +xref: MetaCyc:2.7.8.6-RXN +xref: RHEA:11652 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047361 +name: phosphomannan mannosephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP." [EC:2.7.8.9, MetaCyc:2.7.8.9-RXN] +synonym: "GDP-mannose:phosphomannan mannose phosphotransferase activity" EXACT [EC:2.7.8.9] +xref: EC:2.7.8.9 +xref: MetaCyc:2.7.8.9-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047362 +name: thiosulfate-dithiol sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite." [EC:2.8.1.5, MetaCyc:2.8.1.5-RXN] +synonym: "thiosulfate reductase activity" EXACT [EC:2.8.1.5] +synonym: "thiosulfate:dithioerythritol sulfurtransferase activity" EXACT [EC:2.8.1.5] +synonym: "thiosulphate-dithiol sulphurtransferase activity" EXACT [] +synonym: "TSR" RELATED [EC:2.8.1.5] +xref: EC:2.8.1.5 +xref: MetaCyc:2.8.1.5-RXN +xref: RHEA:15121 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0047363 +name: triglucosylalkylacylglycerol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate." [EC:2.8.2.19, MetaCyc:2.8.2.19-RXN] +synonym: "3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity" EXACT [EC:2.8.2.19] +synonym: "triglucosylalkylacylglycerol sulphotransferase activity" EXACT [] +synonym: "triglucosylmonoalkylmonoacyl sulfotransferase activity" EXACT [EC:2.8.2.19] +xref: EC:2.8.2.19 +xref: MetaCyc:2.8.2.19-RXN +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047364 +name: desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+)." [EC:2.8.2.24, RHEA:20281] +synonym: "3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] +synonym: "3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] +synonym: "desulphoglucosinolate sulphotransferase activity" EXACT [] +synonym: "PAPS-desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] +xref: EC:2.8.2.24 +xref: KEGG_REACTION:R03214 +xref: MetaCyc:2.8.2.24-RXN +xref: RHEA:20281 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047365 +name: quercetin-3-sulfate 3'-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate." [EC:2.8.2.26, RHEA:22504] +synonym: "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] +synonym: "3'-sulfotransferase activity" EXACT [EC:2.8.2.26] +synonym: "flavonol 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] +synonym: "PAPS:flavonol 3-sulfate 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] +synonym: "quercetin-3-sulphate 3'-sulphotransferase activity" EXACT [] +xref: EC:2.8.2.26 +xref: KEGG_REACTION:R02632 +xref: MetaCyc:2.8.2.26-RXN +xref: RHEA:22504 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047366 +name: quercetin-3-sulfate 4'-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate." [EC:2.8.2.27, RHEA:17205] +synonym: "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] +synonym: "flavonol 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] +synonym: "PAPS:flavonol 3-sulfate 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] +synonym: "quercetin-3-sulphate 4'-sulphotransferase activity" EXACT [] +xref: EC:2.8.2.27 +xref: KEGG_REACTION:R02633 +xref: MetaCyc:2.8.2.27-RXN +xref: RHEA:17205 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047367 +name: quercetin-3,3'-bissulfate 7-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate." [EC:2.8.2.28, MetaCyc:2.8.2.28-RXN] +synonym: "3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity" EXACT [EC:2.8.2.28] +synonym: "7-sulfotransferase activity" EXACT [EC:2.8.2.28] +synonym: "flavonol 7-sulfotransferase activity" EXACT [EC:2.8.2.28] +synonym: "PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity" EXACT [EC:2.8.2.28] +synonym: "quercetin-3,3'-bissulphate 7-sulphotransferase activity" EXACT [] +xref: EC:2.8.2.28 +xref: MetaCyc:2.8.2.28-RXN +xref: RHEA:21860 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047368 +name: UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate." [EC:2.8.2.7, RHEA:14337] +synonym: "3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity" EXACT [EC:2.8.2.7] +synonym: "UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity" EXACT [] +synonym: "uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity" EXACT [EC:2.8.2.7] +synonym: "uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity" EXACT [EC:2.8.2.7] +xref: EC:2.8.2.7 +xref: KEGG_REACTION:R04476 +xref: MetaCyc:2.8.2.7-RXN +xref: RHEA:14337 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047369 +name: succinate-hydroxymethylglutarate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate." [EC:2.8.3.13, MetaCyc:2.8.3.13-RXN] +synonym: "dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity" EXACT [EC:2.8.3.13] +synonym: "hydroxymethylglutarate coenzyme A-transferase activity" EXACT [EC:2.8.3.13] +synonym: "succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity" EXACT [EC:2.8.3.13] +xref: EC:2.8.3.13 +xref: MetaCyc:2.8.3.13-RXN +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047370 +name: succinate-citramalate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate." [MetaCyc:2.8.3.7-RXN] +synonym: "citramalate coenzyme A-transferase activity" EXACT [] +synonym: "itaconate CoA-transferase activity" EXACT [] +synonym: "succinyl coenzyme A-citramalyl coenzyme A transferase activity" EXACT [] +synonym: "succinyl-CoA:citramalate CoA-transferase activity" EXACT [] +xref: MetaCyc:2.8.3.7-RXN +xref: RHEA:23528 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047371 +name: butyrate-acetoacetate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate." [EC:2.8.3.9, RHEA:12961] +synonym: "butanoyl-CoA:acetoacetate CoA-transferase activity" EXACT [EC:2.8.3.9] +synonym: "butyryl coenzyme A-acetoacetate coenzyme A-transferase activity" EXACT [EC:2.8.3.9] +synonym: "butyryl-CoA-acetoacetate CoA-transferase activity" EXACT [EC:2.8.3.9] +xref: EC:2.8.3.9 +xref: KEGG_REACTION:R01365 +xref: MetaCyc:2.8.3.9-RXN +xref: RHEA:12961 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047372 +name: acylglycerol lipase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol." [EC:3.1.1.23, MetaCyc:3.1.1.23-RXN] +subset: goslim_chembl +synonym: "fatty acyl monoester lipase activity" EXACT [EC:3.1.1.23] +synonym: "glycerol-ester acylhydrolase activity" EXACT [EC:3.1.1.23] +synonym: "monoacylglycerol hydrolase activity" EXACT [EC:3.1.1.23] +synonym: "monoacylglycerol lipase activity" EXACT [EC:3.1.1.23] +synonym: "monoacylglycerolipase activity" EXACT [EC:3.1.1.23] +synonym: "monoglyceridase activity" EXACT [EC:3.1.1.23] +synonym: "monoglyceride hydrolase activity" EXACT [EC:3.1.1.23] +synonym: "monoglyceride lipase activity" EXACT [EC:3.1.1.23] +synonym: "monoglyceridyllipase activity" EXACT [EC:3.1.1.23] +xref: EC:3.1.1.23 +xref: MetaCyc:3.1.1.23-RXN +xref: Reactome:R-HSA-1482543 "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL" +xref: Reactome:R-HSA-163595 "2-acylglycerol + H2O -> glycerol + fatty acid" +xref: Reactome:R-HSA-192422 "Digestion of triacylglycerols by extracellular PTL:colipase" +xref: Reactome:R-HSA-192425 "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)" +xref: Reactome:R-HSA-192430 "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)" +xref: Reactome:R-HSA-192434 "Digestion of diacylglycerols by extracellular PTL:colipase" +xref: Reactome:R-HSA-192475 "Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2" +xref: Reactome:R-HSA-426032 "DAG is metabolized by DAGL to 2-AG" +xref: Reactome:R-HSA-426043 "2-AG hydrolysis to arachidonate by MAGL" +xref: Reactome:R-HSA-5694462 "ABHD6,12 hydrolyse 3AG" +is_a: GO:0016298 ! lipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047373 +name: acetoxybutynylbithiophene deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)." [EC:3.1.1.54, RHEA:11548] +synonym: "5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity" EXACT [EC:3.1.1.54] +synonym: "5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity" EXACT [EC:3.1.1.54] +synonym: "acetoxybutynylbithiophene esterase activity" EXACT [EC:3.1.1.54] +xref: EC:3.1.1.54 +xref: KEGG_REACTION:R04490 +xref: MetaCyc:3.1.1.54-RXN +xref: RHEA:11548 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047374 +name: methylumbelliferyl-acetate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+)." [EC:3.1.1.56, RHEA:12208] +synonym: "4-methylumbelliferyl-acetate acylhydrolase activity" EXACT [EC:3.1.1.56] +synonym: "esterase D activity" RELATED [EC:3.1.1.56] +xref: EC:3.1.1.56 +xref: KEGG_REACTION:R04141 +xref: MetaCyc:3.1.1.56-RXN +xref: RHEA:12208 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047375 +name: N-acetylgalactosaminoglycan deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan." [EC:3.1.1.58, MetaCyc:3.1.1.58-RXN] +synonym: "N-acetyl galactosaminoglycan deacetylase activity" EXACT [EC:3.1.1.58] +synonym: "N-acetyl-D-galactosaminoglycan acetylhydrolase activity" EXACT [EC:3.1.1.58] +synonym: "polysaccharide deacetylase activity" EXACT [EC:3.1.1.58] +synonym: "Vi-polysaccharide deacetylase activity" EXACT [EC:3.1.1.58] +xref: EC:3.1.1.58 +xref: MetaCyc:3.1.1.58-RXN +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047376 +name: all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate." [MetaCyc:3.1.1.64-RXN, RHEA:13933] +synonym: "all-trans-retinyl-palmitate acylhydrolase activity" BROAD [EC:3.1.1.64] +synonym: "all-trans-retinyl-palmitate hydrolase activity" BROAD [EC:3.1.1.64] +synonym: "retinyl-palmitate palmitohydrolase activity" BROAD [KEGG_REACTION:R02368] +xref: EC:3.1.1 +xref: KEGG_REACTION:R02368 +xref: MetaCyc:3.1.1.64-RXN +xref: Reactome:R-HSA-2404140 "NREH hydrolyses atREs to atROL and FAs" +xref: Reactome:R-HSA-2429643 "NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs" +xref: RHEA:13933 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0047377 +name: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)." [EC:3.1.1.66, RHEA:16313] +synonym: "3,4-diacetoxybutinylbithiophene:4-acetate esterase activity" EXACT [EC:3.1.1.66] +synonym: "5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity" EXACT [EC:3.1.1.66] +synonym: "diacetoxybutynylbithiophene acetate esterase activity" EXACT [EC:3.1.1.66] +xref: EC:3.1.1.66 +xref: KEGG_REACTION:R04525 +xref: MetaCyc:3.1.1.66-RXN +xref: RHEA:16313 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047378 +name: acetylalkylglycerol acetylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+)." [EC:3.1.1.71, RHEA:11552] +synonym: "2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity" EXACT [EC:3.1.1.71] +synonym: "alkylacetylglycerol acetylhydrolase activity" EXACT [EC:3.1.1.71] +xref: EC:3.1.1.71 +xref: KEGG_REACTION:R04043 +xref: MetaCyc:3.1.1.71-RXN +xref: RHEA:11552 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047379 +name: ADP-dependent short-chain-acyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA." [EC:3.1.2.18, MetaCyc:3.1.2.18-RXN] +synonym: "ADP-dependent propionyl coenzyme A hydrolase activity" NARROW [EC:3.1.2.18] +synonym: "ADP-dependent propionyl-CoA hydrolase activity" NARROW [EC:3.1.2.18] +synonym: "ADP-dependent propionyl-CoA thioesterase activity" NARROW [EC:3.1.2.18] +synonym: "ADP-dependent short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] +synonym: "ADP-dependent short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] +synonym: "ADP-dependent short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] +synonym: "ADP-dependent-short-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] +xref: EC:3.1.2.18 +xref: MetaCyc:3.1.2.18-RXN +is_a: GO:0047617 ! acyl-CoA hydrolase activity + +[Term] +id: GO:0047380 +name: ADP-dependent medium-chain-acyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP." [EC:3.1.2.19, MetaCyc:3.1.2.19-RXN] +synonym: "ADP-dependent medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "ADP-dependent medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "ADP-dependent medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "ADP-dependent medium-chain hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "ADP-dependent myristoyl-CoA thioesterase activity" NARROW [EC:3.1.2.19] +synonym: "ADP-dependent-medium-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] +xref: EC:3.1.2.19 +xref: MetaCyc:3.1.2.19-RXN +is_a: GO:0052815 ! medium-chain acyl-CoA hydrolase activity + +[Term] +id: GO:0047381 +name: dodecanoyl-[acyl-carrier-protein] hydrolase activity +namespace: molecular_function +alt_id: GO:0016294 +def: "Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein]." [EC:3.1.2.21, MetaCyc:3.1.2.21-RXN] +synonym: "dodecanoyl-[acyl-carrier protein] hydrolase activity" EXACT [] +synonym: "dodecanoyl-ACP hydrolase activity" EXACT [] +synonym: "dodecanoyl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.21] +synonym: "dodecyl-[acyl-carrier protein] hydrolase activity" EXACT [EC:3.1.2.21] +synonym: "dodecyl-acyl-carrier protein hydrolase" BROAD [EC:3.1.2.21] +synonym: "lauroyl-[acyl-carrier-protein] hydrolase activity" EXACT [] +synonym: "lauroyl-ACP hydrolase activity" EXACT [] +synonym: "lauryl-[acyl-carrier protein] hydrolase activity" EXACT [EC:3.1.2.21] +synonym: "lauryl-acyl-carrier protein hydrolase activity" EXACT [EC:3.1.2.21] +synonym: "lauryl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.21] +xref: EC:3.1.2.21 +xref: MetaCyc:3.1.2.21-RXN +is_a: GO:0016297 ! acyl-[acyl-carrier-protein] hydrolase activity + +[Term] +id: GO:0047382 +name: methylphosphothioglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate." [EC:3.1.3.14, RHEA:16081] +synonym: "methylthiophosphoglycerate phosphatase activity" EXACT [EC:3.1.3.14] +synonym: "S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity" EXACT [EC:3.1.3.14] +xref: EC:3.1.3.14 +xref: KEGG_REACTION:R04317 +xref: MetaCyc:3.1.3.14-RXN +xref: RHEA:16081 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047383 +name: guanidinodeoxy-scyllo-inositol-4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate." [EC:3.1.3.40, RHEA:15777] +synonym: "1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity" EXACT [EC:3.1.3.40] +synonym: "1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity" EXACT [EC:3.1.3.40] +synonym: "1-guanidino-scyllo-inositol 4-phosphatase activity" EXACT [EC:3.1.3.40] +xref: EC:3.1.3.40 +xref: KEGG_REACTION:R03496 +xref: MetaCyc:3.1.3.40-RXN +xref: RHEA:15777 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047384 +name: [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)]." [EC:3.1.3.47, MetaCyc:3.1.3.47-RXN] +synonym: "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity" EXACT [EC:3.1.3.47] +synonym: "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.47] +synonym: "reductase phosphatase activity" BROAD [EC:3.1.3.47] +xref: EC:3.1.3.47 +xref: MetaCyc:3.1.3.47-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0047385 +name: [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]." [EC:3.1.3.52, MetaCyc:3.1.3.52-RXN] +synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity" EXACT [EC:3.1.3.52] +synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.52] +synonym: "branched-chain 2-keto acid dehydrogenase phosphatase activity" EXACT [EC:3.1.3.52] +synonym: "branched-chain alpha-keto acid dehydrogenase phosphatase" BROAD [EC:3.1.3.52] +synonym: "branched-chain oxo-acid dehydrogenase phosphatase activity" RELATED [EC:3.1.3.52] +xref: EC:3.1.3.52 +xref: MetaCyc:3.1.3.52-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0047386 +name: fructose-2,6-bisphosphate 6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate." [EC:3.1.3.54, RHEA:13333] +synonym: "beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] +synonym: "D-fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] +synonym: "fructose 2,6-bisphosphate-6-phosphohydrolase activity" EXACT [EC:3.1.3.54] +synonym: "fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] +xref: EC:3.1.3.54 +xref: KEGG_REACTION:R02730 +xref: MetaCyc:3.1.3.54-RXN +xref: RHEA:13333 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0047387 +name: serine-ethanolaminephosphate phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine." [EC:3.1.4.13, RHEA:17113] +synonym: "SEP diesterase activity" EXACT [EC:3.1.4.13] +synonym: "serine ethanolamine phosphodiester phosphodiesterase activity" EXACT [EC:3.1.4.13] +synonym: "serine-phosphoethanolamine ethanolaminephosphohydrolase activity" EXACT [EC:3.1.4.13] +xref: EC:3.1.4.13 +xref: KEGG_REACTION:R02817 +xref: MetaCyc:3.1.4.13-RXN +xref: RHEA:17113 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047388 +name: [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase +namespace: molecular_function +def: "Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)]." [MetaCyc:3.1.4.15-RXN] +comment: Formerly EC:3.1.4.15. +synonym: "adenylyl(glutamine synthetase) hydrolase activity" EXACT [] +synonym: "adenylyl-[glutamate-ammonia ligase] hydrolase activity" EXACT [] +synonym: "adenylyl-glutamate-ammonia ligase hydrolase activity" EXACT [] +synonym: "adenylyl-glutamine-synthetasehydrolase activity" EXACT [] +synonym: "adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity" EXACT [] +xref: EC:2.7.7.89 +xref: KEGG_REACTION:R03474 +xref: MetaCyc:3.1.4.15-RXN +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0047389 +name: glycerophosphocholine phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline." [EC:3.1.4.2, MetaCyc:3.1.4.2-RXN] +synonym: "glycerolphosphorylcholine phosphodiesterase activity" EXACT [EC:3.1.4.2] +synonym: "glycerophosphinicocholine diesterase activity" EXACT [EC:3.1.4.2] +synonym: "glycerophosphohydrolase activity" EXACT [EC:3.1.4.2] +synonym: "glycerylphosphorylcholinediesterase activity" EXACT [EC:3.1.4.2] +synonym: "sn-glycero-3-phosphocholine glycerophosphohydrolase activity" EXACT [EC:3.1.4.2] +synonym: "sn-glycero-3-phosphorylcholine diesterase activity" EXACT [EC:3.1.4.2] +xref: EC:3.1.4.2 +xref: MetaCyc:3.1.4.2-RXN +xref: Reactome:R-HSA-6814132 "GDPD5 hydrolyzes GPCho" +xref: RHEA:16061 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047390 +name: glycerophosphocholine cholinephosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+)." [EC:3.1.4.38, RHEA:19545] +synonym: "L-3-glycerylphosphinicocholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.38] +synonym: "sn-glycero-3-phosphocholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.38] +xref: EC:3.1.4.38 +xref: KEGG_REACTION:R02591 +xref: MetaCyc:3.1.4.38-RXN +xref: Reactome:R-HSA-6814797 "ENPP6 hydrolyzes lysophosphatidylcholine" +xref: RHEA:19545 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047391 +name: alkylglycerophosphoethanolamine phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate." [EC:3.1.4.39, MetaCyc:3.1.4.39-RXN] +synonym: "1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity" EXACT [EC:3.1.4.39] +synonym: "lysophospholipase D activity" RELATED [EC:3.1.4.39] +xref: EC:3.1.4.39 +xref: MetaCyc:3.1.4.39-RXN +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047392 +name: CMP-N-acylneuraminate phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP." [EC:3.1.4.40, MetaCyc:3.1.4.40-RXN] +synonym: "CMP-N-acetylneuraminate hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "CMP-N-acylneuraminate N-acylneuraminohydrolase activity" EXACT [EC:3.1.4.40] +synonym: "CMP-N-acylneuraminic acid hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "CMP-sialate hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "CMP-sialic acid hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "cytidine monophosphate-N-acetylneuraminic acid hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "cytidine monophosphosialate hydrolase activity" EXACT [EC:3.1.4.40] +synonym: "cytidine monophosphosialic hydrolase activity" EXACT [EC:3.1.4.40] +xref: EC:3.1.4.40 +xref: MetaCyc:3.1.4.40-RXN +xref: RHEA:20185 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047393 +name: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+)." [EC:3.1.4.42, RHEA:16493] +synonym: "rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity" EXACT [EC:3.1.4.42] +synonym: "rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity" EXACT [EC:3.1.4.42] +xref: EC:3.1.4.42 +xref: KEGG_REACTION:R02648 +xref: MetaCyc:3.1.4.42-RXN +xref: RHEA:16493 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047394 +name: glycerophosphoinositol inositolphosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol." [EC:3.1.4.43, MetaCyc:3.1.4.43-RXN] +synonym: "1,2-cyclic-inositol-phosphate phosphodiesterase activity" EXACT [] +synonym: "1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] +synonym: "1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] +synonym: "D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] +synonym: "D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] +synonym: "D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] +synonym: "inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] +xref: EC:3.1.4.43 +xref: MetaCyc:3.1.4.43-RXN +xref: RHEA:14033 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047395 +name: glycerophosphoinositol glycerophosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+)." [EC:3.1.4.44, RHEA:16501] +synonym: "1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] +synonym: "sn-glycero(3)phosphoinositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] +synonym: "sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] +xref: EC:3.1.4.44 +xref: KEGG_REACTION:R01193 +xref: MetaCyc:3.1.4.44-RXN +xref: Reactome:R-HSA-6813740 "GDE1 hydrolyzes GroPIns" +xref: RHEA:16501 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047396 +name: glycosylphosphatidylinositol diacylglycerol-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate." [EC:4.6.1.14, MetaCyc:3.1.4.47-RXN] +synonym: "(glycosyl)phosphatidylinositol-specific phospholipase C activity" EXACT [EC:4.6.1.14] +synonym: "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]" RELATED [EC:4.6.1.14] +synonym: "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity" EXACT [EC:4.6.1.14] +synonym: "glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity" EXACT [EC:4.6.1.14] +synonym: "glycosylphosphatidylinositol-phospholipase C activity" NARROW [EC:4.6.1.14] +synonym: "glycosylphosphatidylinositol-specific phospholipase C activity" EXACT [EC:4.6.1.14] +synonym: "GPI-PLC activity" EXACT [EC:4.6.1.14] +synonym: "GPI-specific phospholipase C activity" EXACT [EC:4.6.1.14] +synonym: "variant-surface-glycoprotein phospholipase C activity" EXACT [] +synonym: "VSG-lipase activity" EXACT [EC:4.6.1.14] +xref: EC:4.6.1.14 +xref: MetaCyc:3.1.4.47-RXN +xref: RHEA:14333 +is_a: GO:0016849 ! phosphorus-oxygen lyase activity + +[Term] +id: GO:0047397 +name: dolichylphosphate-glucose phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose." [EC:3.1.4.48, MetaCyc:3.1.4.48-RXN] +synonym: "Dol-P-Glc phosphodiesterase activity" EXACT [EC:3.1.4.48] +synonym: "dolichol phosphoglucose phosphodiesterase activity" EXACT [EC:3.1.4.48] +synonym: "dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity" EXACT [EC:3.1.4.48] +synonym: "dolichyl-phosphate-glucose phosphodiesterase activity" EXACT [] +xref: EC:3.1.4.48 +xref: MetaCyc:3.1.4.48-RXN +xref: RHEA:13857 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047398 +name: dolichylphosphate-mannose phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose." [EC:3.1.4.49, MetaCyc:3.1.4.49-RXN] +synonym: "dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity" EXACT [EC:3.1.4.49] +synonym: "mannosylphosphodolichol phosphodiesterase activity" EXACT [EC:3.1.4.49] +xref: EC:3.1.4.49 +xref: MetaCyc:3.1.4.49-RXN +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0047399 +name: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate." [EC:3.1.4.51, MetaCyc:3.1.4.51-RXN] +synonym: "6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity" EXACT [EC:3.1.4.51] +synonym: "alpha-glucose-1-phosphate phosphodiesterase activity" EXACT [EC:3.1.4.51] +xref: EC:3.1.4.51 +xref: MetaCyc:3.1.4.51-RXN +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047400 +name: phosphonoacetate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate." [EC:3.11.1.2, RHEA:16749] +synonym: "phosphonoacetate phosphonohydrolase activity" EXACT [EC:3.11.1.2] +xref: EC:3.11.1.2 +xref: KEGG_REACTION:R00318 +xref: MetaCyc:3.11.1.2-RXN +xref: RHEA:16749 +is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds + +[Term] +id: GO:0047401 +name: trithionate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate." [EC:3.12.1.1, RHEA:21884] +synonym: "trithionate thiosulfohydrolase activity" EXACT [EC:3.12.1.1] +xref: EC:3.12.1.1 +xref: KEGG_REACTION:R01930 +xref: MetaCyc:3.12.1.1-RXN +xref: RHEA:21884 +is_a: GO:0016828 ! hydrolase activity, acting on acid sulfur-sulfur bonds + +[Term] +id: GO:0047402 +name: protein-glucosylgalactosylhydroxylysine glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins." [EC:3.2.1.107, MetaCyc:3.2.1.107-RXN] +synonym: "2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity" EXACT [EC:3.2.1.107] +synonym: "protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity" EXACT [EC:3.2.1.107] +xref: EC:3.2.1.107 +xref: MetaCyc:3.2.1.107-RXN +is_a: GO:0015926 ! glucosidase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0047403 +name: lacto-N-biosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc." [EC:3.2.1.140, MetaCyc:3.2.1.140-RXN] +synonym: "oligosaccharide lacto-N-biosylhydrolase activity" RELATED [EC:3.2.1.140] +xref: EC:3.2.1.140 +xref: RHEA:21568 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047404 +name: glucuronosyl-disulfoglucosamine glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine." [EC:3.2.1.56, MetaCyc:3.2.1.56-RXN] +synonym: "3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity" EXACT [EC:3.2.1.56] +synonym: "3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity" EXACT [EC:3.2.1.56] +synonym: "glucuronosyl-disulphoglucosamine glucuronidase activity" EXACT [] +xref: EC:3.2.1.56 +xref: MetaCyc:3.2.1.56-RXN +xref: RHEA:15073 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047405 +name: pyrimidine-5'-nucleotide nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine." [EC:3.2.2.10, MetaCyc:3.2.2.10-RXN] +synonym: "Pyr5N activity" EXACT [EC:3.2.2.10] +synonym: "pyrimidine nucleotide N-ribosidase activity" EXACT [EC:3.2.2.10] +synonym: "pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity" EXACT [EC:3.2.2.10] +xref: EC:3.2.2.10 +xref: MetaCyc:3.2.2.10-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0047406 +name: beta-aspartyl-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine." [EC:3.2.2.11, RHEA:12324] +synonym: "1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity" EXACT [EC:3.2.2.11] +synonym: "beta-aspartylacetylglucosaminidase activity" EXACT [EC:3.2.2.11] +xref: EC:3.2.2.11 +xref: KEGG_REACTION:R01266 +xref: MetaCyc:3.2.2.11-RXN +xref: RHEA:12324 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0047407 +name: ADP-ribosyl-[dinitrogen reductase] hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase]." [EC:3.2.2.24, MetaCyc:3.2.2.24-RXN] +synonym: "ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.24] +synonym: "ADP-ribosyl glycohydrolase activity" EXACT [EC:3.2.2.24] +synonym: "ADP-ribosyl-dinitrogen reductase hydrolase activity" EXACT [EC:3.2.2.24] +synonym: "azoferredoxin glycosidase activity" EXACT [EC:3.2.2.24] +synonym: "azoferredoxin-activating enzymes" RELATED [EC:3.2.2.24] +synonym: "dinitrogenase reductase activating glycohydrolase activity" RELATED [EC:3.2.2.24] +synonym: "dinitrogenase reductase-activating glycohydrolase activity" EXACT [EC:3.2.2.24] +xref: EC:3.2.2.24 +xref: MetaCyc:3.2.2.24-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0047408 +name: alkenylglycerophosphocholine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde." [EC:3.3.2.2, MetaCyc:3.3.2.2-RXN] +synonym: "1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity" EXACT [EC:3.3.2.2] +synonym: "lysoplasmalogenase activity" EXACT [EC:3.3.2.2] +xref: EC:3.3.2.2 +xref: MetaCyc:3.3.2.2-RXN +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0047409 +name: alkenylglycerophosphoethanolamine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde." [EC:3.3.2.5, MetaCyc:3.3.2.5-RXN] +synonym: "1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity" EXACT [EC:3.3.2.5] +xref: EC:3.3.2.5 +xref: MetaCyc:3.3.2.5-RXN +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0047410 +name: N-formylmethionylaminoacyl-tRNA deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate." [MetaCyc:3.5.1.27-RXN] +synonym: "N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity" EXACT [] +xref: MetaCyc:3.5.1.27-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047411 +name: 2-(acetamidomethylene)succinate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate." [EC:3.5.1.29, MetaCyc:3.5.1.29-RXN] +synonym: "2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)" EXACT [EC:3.5.1.29] +synonym: "alpha-(N-acetylaminomethylene)succinic acid hydrolase activity" EXACT [EC:3.5.1.29] +xref: EC:3.5.1.29 +xref: MetaCyc:3.5.1.29-RXN +xref: RHEA:10432 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047412 +name: N-(long-chain-acyl)ethanolamine deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid." [EC:3.5.1.60, MetaCyc:3.5.1.60-RXN] +synonym: "acylethanolamine amidase activity" EXACT [] +synonym: "N-(long-chain-acyl)ethanolamine amidohydrolase activity" EXACT [] +synonym: "N-acylethanolamine amidohydrolase activity" EXACT [] +xref: EC:3.5.1.60 +xref: MetaCyc:3.5.1.60-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047413 +name: N(alpha)-benzyloxycarbonylleucine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2)." [EC:3.5.1.64, RHEA:18901] +synonym: "alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity" EXACT [EC:3.5.1.64] +synonym: "benzyloxycarbonylleucine hydrolase activity" EXACT [EC:3.5.1.64] +synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV" RELATED [EC:3.5.1.64] +synonym: "nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity" EXACT [EC:3.5.1.64] +synonym: "nalpha-benzyloxycarbonylleucine hydrolase activity" EXACT [EC:3.5.1.64] +xref: EC:3.5.1.64 +xref: KEGG_REACTION:R02552 +xref: MetaCyc:3.5.1.64-RXN +xref: RHEA:18901 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047414 +name: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+)." [EC:3.5.1.66, RHEA:17677] +synonym: "2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)" EXACT [EC:3.5.1.66] +synonym: "alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity" EXACT [EC:3.5.1.66] +synonym: "compound B hydrolase activity" EXACT [EC:3.5.1.66] +xref: EC:3.5.1.66 +xref: KEGG_REACTION:R04397 +xref: MetaCyc:3.5.1.66-RXN +xref: RHEA:17677 +xref: Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating\,_decarboxylating) +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047415 +name: D-benzoylarginine-4-nitroanilide amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+)." [EC:3.5.1.72, RHEA:14421] +synonym: "benzoyl-D-arginine arylamidase activity" EXACT [EC:3.5.1.72] +synonym: "D-BAPA-ase activity" EXACT [EC:3.5.1.72] +synonym: "N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity" EXACT [EC:3.5.1.72] +xref: EC:3.5.1.72 +xref: KEGG_REACTION:R04113 +xref: MetaCyc:3.5.1.72-RXN +xref: RHEA:14421 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047416 +name: arylalkyl acylamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine." [EC:3.5.1.76, MetaCyc:3.5.1.76-RXN] +synonym: "aralkyl acylamidase activity" EXACT [EC:3.5.1.76] +synonym: "N-acetylarylalkylamine amidohydrolase activity" EXACT [EC:3.5.1.76] +xref: EC:3.5.1.76 +xref: MetaCyc:3.5.1.76-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047417 +name: N-carbamoyl-D-amino acid hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid." [EC:3.5.1.77, MetaCyc:3.5.1.77-RXN] +synonym: "N-carbamoyl-D-amino acid amidohydrolase activity" EXACT [EC:3.5.1.77] +xref: EC:3.5.1.77 +xref: MetaCyc:3.5.1.77-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047418 +name: phthalyl amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine." [EC:3.5.1.79, MetaCyc:3.5.1.79-RXN] +synonym: "o-phthalyl amidase activity" NARROW [EC:3.5.1.79] +synonym: "phthalyl-amide amidohydrolase activity" EXACT [EC:3.5.1.79] +xref: EC:3.5.1.79 +xref: MetaCyc:3.5.1.79-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047419 +name: N-acetylgalactosamine-6-phosphate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate." [EC:3.5.1.25, MetaCyc:3.5.1.80-RXN] +xref: EC:3.5.1.25 +xref: MetaCyc:3.5.1.80-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0047420 +name: N-acyl-D-amino-acid deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid." [EC:3.5.1.81, MetaCyc:3.5.1.81-RXN] +synonym: "D-aminoacylase activity" EXACT [EC:3.5.1.81] +synonym: "N-acyl-D-amino acid amidohydrolase activity" EXACT [EC:3.5.1.81] +xref: EC:3.5.1.81 +xref: MetaCyc:3.5.1.81-RXN +xref: RHEA:18309 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047421 +name: N-acyl-D-glutamate deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate." [EC:3.5.1.82, RHEA:12833] +synonym: "N-acyl-D-glutamate amidohydrolase activity" EXACT [EC:3.5.1.82] +xref: EC:3.5.1.82 +xref: KEGG_REACTION:R01581 +xref: MetaCyc:3.5.1.82-RXN +xref: RHEA:12833 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047422 +name: N-acyl-D-aspartate deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate." [EC:3.5.1.83, RHEA:18285] +synonym: "N-acyl-D-aspartate amidohydrolase activity" EXACT [EC:3.5.1.83] +xref: EC:3.5.1.83 +xref: KEGG_REACTION:R02182 +xref: MetaCyc:3.5.1.83-RXN +xref: RHEA:18285 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047423 +name: N-methylhydantoinase (ATP-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate." [EC:3.5.2.14, RHEA:11720] +synonym: "methylhydantoin amidase activity" EXACT [EC:3.5.2.14] +synonym: "N-methylhydantoin amidohydrolase activity" EXACT [EC:3.5.2.14] +synonym: "N-methylhydantoin hydrolase activity" EXACT [EC:3.5.2.14] +synonym: "N-methylhydantoinase (ATP-hydrolysing)" EXACT [EC:3.5.2.14] +synonym: "N-methylhydantoinase activity" EXACT [EC:3.5.2.14] +synonym: "N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)" EXACT [EC:3.5.2.14] +xref: EC:3.5.2.14 +xref: KEGG_REACTION:R03187 +xref: MetaCyc:3.5.2.14-RXN +xref: RHEA:11720 +xref: Wikipedia:N-methylhydantoinase_(ATP-hydrolysing) +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0047424 +name: methylenediurea deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea." [EC:3.5.3.21, MetaCyc:3.5.3.21-RXN, RHEA:15929] +synonym: "methylenediurea aminohydrolase activity" EXACT [EC:3.5.3.21] +synonym: "methylenediurease activity" EXACT [EC:3.5.3.21] +xref: EC:3.5.3.21 +xref: MetaCyc:3.5.3.21-RXN +xref: RHEA:15929 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047425 +name: 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+)." [EC:3.5.4.22, RHEA:10560] +synonym: "1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)" EXACT [EC:3.5.4.22] +synonym: "HPC deaminase activity" EXACT [EC:3.5.4.22] +xref: EC:3.5.4.22 +xref: KEGG_REACTION:R02280 +xref: MetaCyc:3.5.4.22-RXN +xref: RHEA:10560 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047426 +name: ricinine nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone." [EC:3.5.5.2, MetaCyc:3.5.5.2-RXN] +synonym: "ricinine aminohydrolase activity" EXACT [EC:3.5.5.2] +xref: EC:3.5.5.2 +xref: MetaCyc:3.5.5.2-RXN +xref: RHEA:22704 +is_a: GO:0000257 ! nitrilase activity + +[Term] +id: GO:0047427 +name: cyanoalanine nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+)." [EC:3.5.5.4, RHEA:11188] +synonym: "3-cyano-L-alanine aminohydrolase activity" EXACT [EC:3.5.5.4] +synonym: "beta-cyanoalanine nitrilase activity" EXACT [EC:3.5.5.4] +xref: EC:3.5.5.4 +xref: KEGG_REACTION:R00486 +xref: MetaCyc:3.5.5.4-RXN +xref: RHEA:11188 +is_a: GO:0000257 ! nitrilase activity + +[Term] +id: GO:0047428 +name: arylacetonitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3." [EC:3.5.5.5, MetaCyc:3.5.5.5-RXN] +synonym: "arylacetonitrile aminohydrolase activity" EXACT [EC:3.5.5.5] +xref: EC:3.5.5.5 +xref: MetaCyc:3.5.5.5-RXN +xref: RHEA:20657 +is_a: GO:0000257 ! nitrilase activity + +[Term] +id: GO:0047429 +name: nucleoside-triphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide." [MetaCyc:3.6.1.19-RXN] +synonym: "nucleoside-triphosphate diphosphohydrolase activity" EXACT [EC:3.6.1.9] +synonym: "nucleoside-triphosphate pyrophosphatase activity" EXACT [EC:3.6.1.9] +xref: EC:3.6.1.9 +xref: MetaCyc:3.6.1.19-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047430 +name: oligosaccharide-diphosphodolichol diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate." [EC:3.6.1.44, MetaCyc:3.6.1.44-RXN] +synonym: "oligosaccharide-diphosphodolichol phosphodolichohydrolase activity" EXACT [EC:3.6.1.44] +synonym: "oligosaccharide-diphosphodolichol pyrophosphatase activity" EXACT [] +xref: EC:3.6.1.44 +xref: MetaCyc:3.6.1.44-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047431 +name: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2)." [EC:4.1.1.51, RHEA:13669] +synonym: "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)" EXACT [EC:4.1.1.51] +synonym: "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity" EXACT [EC:4.1.1.51] +xref: EC:4.1.1.51 +xref: KEGG_REACTION:R03461 +xref: MetaCyc:4.1.1.51-RXN +xref: RHEA:13669 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047432 +name: 2,2-dialkylglycine decarboxylase (pyruvate) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone." [EC:4.1.1.64, RHEA:16073] +synonym: "2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity" EXACT [EC:4.1.1.64] +synonym: "2,2-dialkylglycine carboxy-lyase (amino-transferring)" EXACT [EC:4.1.1.64] +synonym: "2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)" EXACT [EC:4.1.1.64] +synonym: "alpha-dialkyl amino acid transaminase activity" EXACT [EC:4.1.1.64] +synonym: "dialkyl amino acid (pyruvate) decarboxylase activity" EXACT [EC:4.1.1.64] +synonym: "dialkylamino-acid decarboxylase (pyruvate)" EXACT [EC:4.1.1.64] +synonym: "L-alanine-alpha-ketobutyrate aminotransferase activity" EXACT [EC:4.1.1.64] +xref: EC:4.1.1.64 +xref: KEGG_REACTION:R03854 +xref: MetaCyc:4.1.1.64-RXN +xref: RHEA:16073 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047433 +name: branched-chain-2-oxoacid decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2)." [EC:4.1.1.72, RHEA:21108] +synonym: "(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)" EXACT [EC:4.1.1.72] +synonym: "(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity" EXACT [EC:4.1.1.72] +synonym: "BCKA" RELATED [EC:4.1.1.72] +synonym: "branched-chain alpha-keto acid decarboxylase activity" EXACT [EC:4.1.1.72] +synonym: "branched-chain keto acid decarboxylase activity" EXACT [EC:4.1.1.72] +synonym: "branched-chain oxo acid decarboxylase activity" EXACT [EC:4.1.1.72] +xref: EC:4.1.1.72 +xref: KEGG_REACTION:R03894 +xref: MetaCyc:4.1.1.72-RXN +xref: RHEA:21108 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047434 +name: indolepyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde." [EC:4.1.1.74, MetaCyc:4.1.1.74-RXN] +synonym: "3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]" RELATED [EC:4.1.1.74] +synonym: "3-(indol-3-yl)pyruvate carboxy-lyase activity" EXACT [EC:4.1.1.74] +synonym: "indol-3-yl-pyruvate carboxy-lyase activity" EXACT [EC:4.1.1.74] +synonym: "indole-3-pyruvate decarboxylase activity" EXACT [EC:4.1.1.74] +xref: EC:4.1.1.74 +xref: MetaCyc:4.1.1.74-RXN +xref: RHEA:18017 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047435 +name: 5-guanidino-2-oxopentanoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2)." [EC:4.1.1.75, RHEA:11340] +synonym: "2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)" EXACT [EC:4.1.1.75] +synonym: "2-oxo-5-guanidinopentanoate carboxy-lyase activity" EXACT [EC:4.1.1.75] +synonym: "2-oxo-5-guanidinopentanoate decarboxylase activity" EXACT [EC:4.1.1.75] +synonym: "2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity" EXACT [EC:4.1.1.75] +synonym: "alpha-ketoarginine decarboxylase activity" EXACT [EC:4.1.1.75] +xref: EC:4.1.1.75 +xref: KEGG_REACTION:R03178 +xref: MetaCyc:4.1.1.75-RXN +xref: RHEA:11340 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047436 +name: arylmalonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2)." [EC:4.1.1.76, RHEA:20513] +synonym: "2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)" EXACT [EC:4.1.1.76] +synonym: "2-aryl-2-methylmalonate carboxy-lyase activity" EXACT [EC:4.1.1.76] +synonym: "AMDASE" RELATED [EC:4.1.1.76] +synonym: "AMDase activity" EXACT [EC:4.1.1.76] +xref: EC:4.1.1.76 +xref: KEGG_REACTION:R05173 +xref: MetaCyc:4.1.1.76-RXN +xref: RHEA:20513 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047437 +name: 4-oxalocrotonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate." [EC:4.1.1.77, MetaCyc:4.1.1.77-RXN] +synonym: "4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming)" EXACT [EC:4.1.1.77] +synonym: "4-oxalocrotonate carboxy-lyase activity" EXACT [EC:4.1.1.77] +xref: EC:4.1.1.77 +xref: MetaCyc:4.1.1.77-RXN +xref: RHEA:24260 +xref: UM-BBD_reactionID:r1435 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047438 +name: 2-dehydro-3-deoxy-L-pentonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate." [EC:4.1.2.18, MetaCyc:4.1.2.18-RXN] +synonym: "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.18] +synonym: "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity" EXACT [EC:4.1.2.18] +synonym: "2-keto-3-deoxy-D-xylonate aldolase activity" EXACT [EC:4.1.2.18] +synonym: "2-keto-3-deoxy-L-arabonate aldolase activity" NARROW [EC:4.1.2.18] +synonym: "2-keto-3-deoxy-L-pentonate aldolase activity" EXACT [EC:4.1.2.18] +synonym: "3-deoxy-D-pentulosonic acid aldolase" BROAD [EC:4.1.2.18] +xref: EC:4.1.2.18 +xref: MetaCyc:4.1.2.18-RXN +xref: RHEA:18545 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047439 +name: 3-deoxy-D-manno-octulosonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate." [EC:4.1.2.23, RHEA:23340] +synonym: "2-keto-3-deoxyoctonate aldolase activity" EXACT [EC:4.1.2.23] +synonym: "2-keto-3-deoxyoctonic aldolase activity" EXACT [EC:4.1.2.23] +synonym: "3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)" EXACT [EC:4.1.2.23] +synonym: "3-deoxy-D-manno-octulosonate D-arabinose-lyase activity" EXACT [EC:4.1.2.23] +synonym: "3-deoxy-D-manno-octulosonic aldolase activity" EXACT [EC:4.1.2.23] +synonym: "3-deoxyoctulosonic aldolase activity" EXACT [EC:4.1.2.23] +synonym: "KDOaldolase activity" EXACT [EC:4.1.2.23] +xref: EC:4.1.2.23 +xref: KEGG_REACTION:R01576 +xref: MetaCyc:4.1.2.23-RXN +xref: RHEA:23340 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047440 +name: 2-dehydro-3-deoxy-D-pentonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate." [EC:4.1.2.28, RHEA:20609] +synonym: "2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity" EXACT [EC:4.1.2.28] +synonym: "2-keto-3-deoxy-D-pentonate aldolase activity" EXACT [EC:4.1.2.28] +synonym: "3-deoxy-D-pentulosonic acid aldolase" BROAD [EC:4.1.2.28] +xref: EC:4.1.2.28 +xref: KEGG_REACTION:R01782 +xref: MetaCyc:4.1.2.28-RXN +xref: RHEA:20609 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047441 +name: 5-dehydro-2-deoxyphosphogluconate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate." [EC:4.1.2.29, RHEA:13177] +synonym: "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.29] +synonym: "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity" EXACT [EC:4.1.2.29] +synonym: "phospho-5-dehydro-2-deoxygluconate aldolase activity" EXACT [EC:4.1.2.29] +synonym: "phospho-5-keto-2-deoxygluconate aldolase activity" EXACT [EC:4.1.2.29] +xref: EC:4.1.2.29 +xref: KEGG_REACTION:R05378 +xref: MetaCyc:4.1.2.29-RXN +xref: RHEA:13177 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047442 +name: 17-alpha-hydroxyprogesterone aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione." [EC:4.1.2.30, MetaCyc:4.1.2.30-RXN] +synonym: "17-alpha-hydroxyprogesterone acetaldehyde-lyase activity" EXACT [EC:4.1.2.30] +synonym: "17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)" EXACT [EC:4.1.2.30] +synonym: "17alpha-hydroxyprogesterone acetaldehyde-lyase activity" EXACT [EC:4.1.2.30] +synonym: "17alpha-hydroxyprogesterone aldolase activity" EXACT [EC:4.1.2.30] +synonym: "C-17/C-20 lyase activity" EXACT [EC:4.1.2.30] +xref: EC:4.1.2.30 +xref: MetaCyc:4.1.2.30-RXN +xref: RHEA:14753 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047443 +name: 4-hydroxy-4-methyl-2-oxoglutarate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate." [EC:4.1.3.17, MetaCyc:4.1.3.17-RXN] +synonym: "4-hydroxy-4-methyl-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.17] +synonym: "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)" EXACT [EC:4.1.3.17] +synonym: "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity" EXACT [EC:4.1.3.17] +synonym: "gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity" EXACT [EC:4.1.3.17] +synonym: "pyruvate aldolase activity" EXACT [EC:4.1.3.17] +xref: EC:4.1.3.17 +xref: MetaCyc:4.1.3.17-RXN +xref: RHEA:22748 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047444 +name: N-acylneuraminate-9-phosphate synthase activity +namespace: molecular_function +alt_id: GO:0019007 +def: "Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate." [EC:2.5.1.57, MetaCyc:4.1.3.20-RXN] +synonym: "N-acetylneuraminate 9-phosphate lyase activity" EXACT [EC:2.5.1.57] +synonym: "N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity" EXACT [EC:2.5.1.57] +synonym: "N-acetylneuraminate 9-phosphate synthetase activity" EXACT [EC:2.5.1.57] +synonym: "N-acetylneuraminic acid phosphate synthase activity" EXACT [GOC:mah] +synonym: "N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.57] +synonym: "phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity" EXACT [EC:2.5.1.57] +synonym: "sialic acid 9-phosphate synthetase activity" EXACT [EC:2.5.1.57] +xref: EC:2.5.1.57 +xref: MetaCyc:4.1.3.20-RXN +xref: Reactome:R-HSA-4084976 "NANS converts ManNAc-6-P to Neu5Ac-9-P" +xref: RHEA:13421 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047445 +name: 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate." [EC:4.1.3.26, RHEA:23084] +synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)" EXACT [EC:4.1.3.26] +synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity" EXACT [EC:4.1.3.26] +synonym: "3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.26] +synonym: "3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity" EXACT [EC:4.1.3.26] +synonym: "beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity" EXACT [EC:4.1.3.26] +synonym: "hydroxyisohexenylglutaryl-CoA:acetatelyase activity" EXACT [EC:4.1.3.26] +xref: EC:4.1.3.26 +xref: KEGG_REACTION:R08090 +xref: MetaCyc:4.1.3.26-RXN +xref: RHEA:23084 +xref: UM-BBD_reactionID:r1168 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047446 +name: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone." [EC:4.1.3.35, RHEA:23868] +synonym: "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.35] +synonym: "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity" EXACT [EC:4.1.3.35] +xref: EC:4.1.3.35 +xref: KEGG_REACTION:R02232 +xref: MetaCyc:4.1.3.35-RXN +xref: RHEA:23868 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047447 +name: erythro-3-hydroxyaspartate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid." [EC:4.3.1.20, MetaCyc:4.3.1.20-RXN] +synonym: "3-hydroxyaspartate dehydratase activity" BROAD [EC:4.3.1.20] +synonym: "erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.20] +synonym: "erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)" EXACT [EC:4.3.1.20] +synonym: "erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.20] +synonym: "erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)" EXACT [EC:4.3.1.20] +synonym: "erythro-3-hydroxyaspartate dehydratase activity" EXACT [] +synonym: "erythro-beta-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.20] +xref: EC:4.3.1.20 +xref: MetaCyc:4.3.1.20-RXN +xref: RHEA:19757 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0047448 +name: 5-dehydro-4-deoxyglucarate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O." [EC:4.2.1.41, RHEA:24608] +synonym: "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.41] +synonym: "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)" EXACT [EC:4.2.1.41] +synonym: "5-keto-4-deoxy-glucarate dehydratase activity" EXACT [EC:4.2.1.41] +synonym: "D-4-deoxy-5-ketoglucarate hydro-lyase activity" EXACT [EC:4.2.1.41] +synonym: "deoxyketoglucarate dehydratase activity" EXACT [EC:4.2.1.41] +xref: EC:4.2.1.41 +xref: KEGG_REACTION:R02279 +xref: MetaCyc:4.2.1.41-RXN +xref: RHEA:24608 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047449 +name: 2-dehydro-3-deoxy-L-arabinonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O." [EC:4.2.1.43, RHEA:17201] +synonym: "2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)" EXACT [EC:4.2.1.43] +synonym: "2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.43] +synonym: "2-keto-3-deoxy-L-arabinonate dehydratase activity" EXACT [EC:4.2.1.43] +xref: EC:4.2.1.43 +xref: KEGG_REACTION:R02278 +xref: MetaCyc:4.2.1.43-RXN +xref: RHEA:17201 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047450 +name: crotonoyl-[acyl-carrier-protein] hydratase activity +namespace: molecular_function +alt_id: GO:0080063 +def: "Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein]." [EC:4.2.1.58, MetaCyc:4.2.1.58-RXN] +synonym: "(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.58] +synonym: "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)" EXACT [EC:4.2.1.58] +synonym: "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.58] +synonym: "3-hydroxybutyryl acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.58] +synonym: "beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity" EXACT [EC:4.2.1.58] +synonym: "beta-hydroxybutyryl acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.58] +synonym: "crotonoyl-[acyl-carrier protein] hydratase activity" EXACT [] +synonym: "crotonoyl-ACP hydratase activity" EXACT [] +synonym: "crotonoyl-acyl-carrier-protein hydratase activity" EXACT [EC:4.2.1.58] +synonym: "crotonyl acyl carrier protein hydratase activity" EXACT [EC:4.2.1.58] +synonym: "enoyl acyl carrier protein hydrase activity" EXACT [EC:4.2.1.58] +xref: EC:4.2.1.58 +xref: KEGG_REACTION:R04428 +xref: MetaCyc:4.2.1.58-RXN +is_a: GO:0019171 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity + +[Term] +id: GO:0047451 +name: 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]." [EC:4.2.1.59, MetaCyc:4.2.1.59-RXN, PMID:8910376, RHEA:41844] +synonym: "(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.59] +synonym: "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)" EXACT [EC:4.2.1.59] +synonym: "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.59] +synonym: "3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity" EXACT [] +synonym: "3-hydroxyoctanoyl-ACP dehydratase activity" EXACT [] +synonym: "3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxyoctanoyl thioester dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxyoctanoyl-ACP-dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity" EXACT [EC:4.2.1.59] +synonym: "D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.59] +xref: EC:4.2.1.59 +xref: KEGG_REACTION:R04537 +xref: MetaCyc:4.2.1.59-RXN +xref: RHEA:41844 +is_a: GO:0019171 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity + +[Term] +id: GO:0047452 +name: protoaphin-aglucone dehydratase (cyclizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin." [EC:4.2.1.73, RHEA:23876] +synonym: "protoaphin dehydratase (cyclizing)" EXACT [EC:4.2.1.73] +synonym: "protoaphin dehydratase activity" EXACT [EC:4.2.1.73] +synonym: "protoaphin-aglucone hydro-lyase (cyclizing)" EXACT [EC:4.2.1.73] +synonym: "protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)" EXACT [EC:4.2.1.73] +xref: EC:4.2.1.73 +xref: KEGG_REACTION:R03742 +xref: MetaCyc:4.2.1.73-RXN +xref: RHEA:23876 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047453 +name: ATP-dependent NAD(P)H-hydrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate." [EC:4.2.1.93, RHEA:19017] +synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)" EXACT [EC:4.2.1.93] +synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming)" RELATED [EC:4.2.1.93] +synonym: "ATP-dependent H(4)NAD(P)OH dehydratase activity" EXACT [] +synonym: "ATP-dependent H4NAD(P)OH dehydratase activity" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide hydrate dehydratase activity" BROAD [EC:4.2.1.93] +xref: EC:4.2.1.93 +xref: KEGG_REACTION:R00129 +xref: MetaCyc:4.2.1.93-RXN +xref: Reactome:R-HSA-6806967 "CARKD dehydrates S-NAD(P)HX to NADPH" +xref: RHEA:19017 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047454 +name: phaseollidin hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin." [EC:4.2.1.97, RHEA:19769] +synonym: "phaseollidin-hydrate hydro-lyase (phaseollidin-forming)" EXACT [EC:4.2.1.97] +synonym: "phaseollidin-hydrate hydro-lyase activity" EXACT [EC:4.2.1.97] +xref: EC:4.2.1.97 +xref: KEGG_REACTION:R04728 +xref: MetaCyc:4.2.1.97-RXN +xref: RHEA:19769 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047455 +name: 16-alpha-hydroxyprogesterone dehydratase activity +namespace: molecular_function +alt_id: GO:0047523 +def: "Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone." [EC:4.2.1.98, MetaCyc:4.2.1.98-RXN] +synonym: "16-alpha-dehydroxylase activity" EXACT [EC:4.2.1.98] +synonym: "16-alpha-hydroxyprogesterone dehydroxylase activity" EXACT [EC:4.2.1.98] +synonym: "16-dehydroprogesterone hydratase activity" RELATED [] +synonym: "16alpha-dehydroxylase activity" EXACT [EC:4.2.1.98] +synonym: "16alpha-hydroxyprogesterone dehydratase activity" EXACT [EC:4.2.1.98] +synonym: "16alpha-hydroxyprogesterone dehydroxylase activity" EXACT [EC:4.2.1.98] +synonym: "16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)" EXACT [EC:4.2.1.98] +synonym: "16alpha-hydroxyprogesterone hydro-lyase activity" EXACT [EC:4.2.1.98] +synonym: "hydroxyprogesterone dehydroxylase activity" EXACT [] +xref: EC:4.2.1.98 +xref: MetaCyc:4.2.1.98-RXN +xref: RHEA:12584 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047456 +name: 2-methylisocitrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O." [EC:4.2.1.99, RHEA:17941] +synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]" RELATED [EC:4.2.1.99] +synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.99] +xref: EC:4.2.1.99 +xref: KEGG_REACTION:R04425 +xref: MetaCyc:4.2.1.99-RXN +xref: RHEA:17941 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047457 +name: exo-(1,4)-alpha-D-glucan lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose." [EC:4.2.2.13, MetaCyc:4.2.2.13-RXN] +synonym: "(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)" EXACT [EC:4.2.2.13] +synonym: "alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity" EXACT [EC:4.2.2.13] +synonym: "alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity" EXACT [EC:4.2.2.13] +synonym: "alpha-1,4-glucan exo-lyase activity" EXACT [EC:4.2.2.13] +synonym: "alpha-1,4-glucan lyase activity" BROAD [EC:4.2.2.13] +synonym: "exo-(1->4)-alpha-D-glucan lyase activity" EXACT [EC:4.2.2.13] +synonym: "exo-alpha-1,4-glucan lyase activity" EXACT [EC:4.2.2.13] +xref: EC:4.2.2.13 +xref: MetaCyc:4.2.2.13-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047458 +name: beta-pyrazolylalanine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)." [EC:2.5.1.51, RHEA:13117] +synonym: "3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.51] +synonym: "beta-(1-pyrazolyl)alanine synthase activity" EXACT [EC:2.5.1.51] +synonym: "beta-pyrazolealanine synthase activity" EXACT [EC:2.5.1.51] +synonym: "beta-pyrazolylalanine synthase (acetylserine) activity" EXACT [] +synonym: "BPA-synthase activity" EXACT [EC:2.5.1.51] +synonym: "O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity" EXACT [EC:2.5.1.51] +synonym: "O3-acetyl-L-serine acetate-lyase (adding pyrazole)" EXACT [EC:2.5.1.51] +synonym: "O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.51] +synonym: "pyrazolealanine synthase activity" EXACT [EC:2.5.1.51] +synonym: "pyrazolylalaninase activity" EXACT [EC:2.5.1.51] +xref: EC:2.5.1.51 +xref: KEGG_REACTION:R03134 +xref: MetaCyc:2.5.1.51-RXN +xref: RHEA:13117 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047459 +name: 3-aminobutyryl-CoA ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+)." [EC:4.3.1.14, RHEA:10056] +synonym: "L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)" EXACT [EC:4.3.1.14] +synonym: "L-3-aminobutyryl-CoA ammonia-lyase activity" EXACT [EC:4.3.1.14] +synonym: "L-3-aminobutyryl-CoA deaminase activity" EXACT [EC:4.3.1.14] +xref: EC:4.3.1.14 +xref: KEGG_REACTION:R03030 +xref: MetaCyc:4.3.1.14-RXN +xref: RHEA:10056 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0047460 +name: L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+)." [EC:4.5.1.4, RHEA:11620] +synonym: "L-2-amino-4-chloro-4-pentenoate dehalogenase activity" EXACT [EC:4.5.1.4] +synonym: "L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)" EXACT [EC:4.5.1.4] +synonym: "L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating)" EXACT [EC:4.5.1.4] +xref: EC:4.5.1.4 +xref: KEGG_REACTION:R02605 +xref: MetaCyc:4.5.1.4-RXN +xref: RHEA:11620 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0047461 +name: (+)-delta-cadinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene." [EC:4.2.3.13, MetaCyc:4.6.1.11-RXN] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)" EXACT [EC:4.2.3.13] +synonym: "D-cadinene synthase activity" EXACT [EC:4.2.3.13] +xref: EC:4.2.3.13 +xref: MetaCyc:4.6.1.11-RXN +xref: RHEA:19525 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0047462 +name: phenylalanine racemase (ATP-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+)." [EC:5.1.1.11, RHEA:20201] +synonym: "gramicidin S synthetase I" RELATED [EC:5.1.1.11] +synonym: "phenylalanine racemase (adenosine triphosphate-hydrolysing)" EXACT [EC:5.1.1.11] +synonym: "phenylalanine racemase (ATP-hydrolysing)" BROAD [EC:5.1.1.11] +synonym: "phenylalanine racemase activity" EXACT [EC:5.1.1.11] +xref: EC:5.1.1.11 +xref: KEGG_REACTION:R00686 +xref: MetaCyc:5.1.1.11-RXN +xref: RHEA:20201 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0047463 +name: 2-aminohexano-6-lactam racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam." [EC:5.1.1.15, RHEA:14813] +synonym: "2-amino-hexano-6-lactam racemase activity" EXACT [EC:5.1.1.15] +synonym: "alpha-amino-epsilon-caprolactam racemase activity" EXACT [EC:5.1.1.15] +xref: EC:5.1.1.15 +xref: KEGG_REACTION:R04736 +xref: MetaCyc:5.1.1.15-RXN +xref: RHEA:14813 +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives + +[Term] +id: GO:0047464 +name: heparosan-N-sulfate-glucuronate 5-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate." [EC:5.1.3.17, MetaCyc:5.1.3.17-RXN] +synonym: "C-5 uronosyl epimerase activity" EXACT [EC:5.1.3.17] +synonym: "D-glucuronyl C-5 epimerase activity" EXACT [EC:5.1.3.17] +synonym: "heparosan epimerase activity" EXACT [EC:5.1.3.17] +synonym: "heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity" EXACT [EC:5.1.3.17] +synonym: "heparosan-N-sulphate-glucuronate 5-epimerase activity" EXACT [] +synonym: "poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity" EXACT [EC:5.1.3.17] +synonym: "polyglucuronate epimerase activity" EXACT [EC:5.1.3.17] +xref: EC:5.1.3.17 +xref: MetaCyc:5.1.3.17-RXN +xref: RHEA:20197 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047465 +name: N-acylglucosamine-6-phosphate 2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate." [EC:5.1.3.9, MetaCyc:5.1.3.9-RXN] +synonym: "acylglucosamine phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +synonym: "acylglucosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +synonym: "acylmannosamine phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +synonym: "N-acetylglucosmamine 6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +synonym: "N-acetylmannosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +synonym: "N-acyl-D-glucosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] +xref: EC:5.1.3.9 +xref: MetaCyc:5.1.3.9-RXN +xref: RHEA:23932 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047466 +name: 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity +namespace: molecular_function +alt_id: GO:0018840 +def: "Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide." [EC:5.2.1.10, RHEA:10924] +synonym: "2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity" EXACT [EC:5.2.1.10] +synonym: "2-chlorocarboxymethylenebutenolide isomerase activity" EXACT [EC:5.2.1.-] +synonym: "chlorodienelactone isomerase activity" EXACT [EC:5.2.1.-] +xref: EC:5.2.1.10 +xref: KEGG_REACTION:R04576 +xref: MetaCyc:5.2.1.10-RXN +xref: RHEA:10924 +xref: UM-BBD_reactionID:r0278 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0047467 +name: 4-hydroxyphenylacetaldehyde-oxime isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime." [EC:5.2.1.11, MetaCyc:5.2.1.11-RXN] +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0047468 +name: phosphoglucomutase (glucose-cofactor) activity +namespace: molecular_function +def: "Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor." [EC:5.4.2.5, MetaCyc:5.4.2.5-RXN] +synonym: "alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)" EXACT [EC:5.4.2.5] +synonym: "glucose-1-phosphate phosphotransferase activity" EXACT [EC:5.4.2.5] +xref: EC:5.4.2.5 +xref: MetaCyc:5.4.2.5-RXN +is_a: GO:0004614 ! phosphoglucomutase activity + +[Term] +id: GO:0047469 +name: 4-carboxymethyl-4-methylbutenolide mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide." [EC:5.4.99.14, RHEA:19237] +synonym: "4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity" EXACT [EC:5.4.99.14] +synonym: "4-methyl-2-enelactone isomerase activity" EXACT [EC:5.4.99.14] +synonym: "4-methyl-2-enelactone methyl-isomerase activity" EXACT [EC:5.4.99.14] +synonym: "4-methyl-3-enelactone methyl isomerase activity" EXACT [EC:5.4.99.14] +synonym: "4-methylmuconolactone methylisomerase activity" EXACT [EC:5.4.99.14] +xref: EC:5.4.99.14 +xref: KEGG_REACTION:R04510 +xref: MetaCyc:5.4.99.14-RXN +xref: RHEA:19237 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047470 +name: (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside." [EC:5.4.99.15, MetaCyc:5.4.99.15-RXN] +synonym: "(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase" BROAD [EC:5.4.99.15] +synonym: "malto-oligosyltrehalose synthase activity" EXACT [EC:5.4.99.15] +synonym: "maltodextrin alpha-D-glucosyltransferase activity" EXACT [EC:5.4.99.15] +xref: EC:5.4.99.15 +xref: MetaCyc:5.4.99.15-RXN +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047471 +name: maltose alpha-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: maltose = trehalose." [EC:5.4.99.16, MetaCyc:5.4.99.16-RXN] +synonym: "maltose alpha-D-glucosylmutase activity" EXACT [EC:5.4.99.16] +synonym: "maltose glucosylmutase activity" EXACT [EC:5.4.99.16] +synonym: "trehalose synthase activity" RELATED [EC:5.4.99.16] +xref: EC:5.4.99.16 +xref: MetaCyc:5.4.99.16-RXN +xref: RHEA:15145 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047472 +name: 3-carboxy-cis,cis-muconate cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+)." [EC:5.5.1.2, RHEA:23656] +synonym: "2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.2] +synonym: "3-carboxymuconate lactonizing enzyme activity" EXACT [EC:5.5.1.2] +synonym: "3-carboxymuconolactone hydrolase activity" EXACT [EC:5.5.1.2] +synonym: "beta-carboxymuconate lactonizing enzyme activity" EXACT [EC:5.5.1.2] +synonym: "CMLE activity" EXACT [EC:5.5.1.2] +xref: EC:5.5.1.2 +xref: KEGG_REACTION:R03307 +xref: MetaCyc:5.5.1.2-RXN +xref: RHEA:23656 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0047473 +name: D-alanine [D-alanyl carrier protein] ligase activity +namespace: molecular_function +def: "Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate." [GOC:pg] +synonym: "D-alanine-activating enzyme activity" RELATED [] +synonym: "D-alanine-D-alanyl carrier protein ligase activity" EXACT [EC:6.2.1] +synonym: "D-alanine-poly(phosphoribitol) ligase activity" BROAD [] +synonym: "D-alanine:poly(phosphoribitol) ligase (AMP-forming)" BROAD [] +xref: EC:6.2.1 +xref: MetaCyc:6.2.1.M5-RXN +is_a: GO:0016878 ! acid-thiol ligase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14237 xsd:anyURI + +[Term] +id: GO:0047474 +name: long-chain fatty acid luciferin component ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22." [EC:6.2.1.19, MetaCyc:6.2.1.19-RXN] +synonym: "acyl-protein synthetase activity" RELATED [EC:6.2.1.19] +synonym: "long-chain-fatty-acid luciferin component ligase activity" EXACT [GOC:mah] +synonym: "long-chain-fatty-acid-luciferin-component ligase activity" EXACT [] +synonym: "long-chain-fatty-acid:protein ligase (AMP-forming)" EXACT [EC:6.2.1.19] +xref: EC:6.2.1.19 +xref: MetaCyc:6.2.1.19-RXN +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047475 +name: phenylacetate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA." [EC:6.2.1.30, RHEA:20956] +synonym: "PA-CoA ligase activity" EXACT [EC:6.2.1.30] +synonym: "phenacyl coenzyme A synthetase activity" EXACT [EC:6.2.1.30] +synonym: "phenylacetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.30] +synonym: "phenylacetyl-CoA ligase (AMP-forming)" EXACT [EC:6.2.1.30] +synonym: "phenylacetyl-CoA ligase activity" EXACT [EC:6.2.1.30] +xref: EC:6.2.1.30 +xref: KEGG_REACTION:R02539 +xref: MetaCyc:PHENYLACETATE--COA-LIGASE-RXN +xref: RHEA:20956 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047476 +name: 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP." [EC:6.2.1.28, MetaCyc:6.2.1.28-RXN] +synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity" EXACT [EC:6.2.1.28] +synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.28] +synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.28] +synonym: "DHCA-CoA ligase activity" EXACT [EC:6.2.1.28] +xref: EC:6.2.1.28 +xref: MetaCyc:6.2.1.28-RXN +xref: RHEA:21776 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047478 +name: aspartate-ammonia ligase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate." [EC:6.3.1.4, RHEA:14197] +synonym: "asparagine synthetase (adenosine diphosphate-forming)" EXACT [EC:6.3.1.4] +synonym: "asparagine synthetase (ADP-forming) activity" EXACT [EC:6.3.1.4] +synonym: "L-aspartate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.1.4] +xref: EC:6.3.1.4 +xref: KEGG_REACTION:R00482 +xref: MetaCyc:6.3.1.4-RXN +xref: RHEA:14197 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0047479 +name: trypanothione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate." [EC:6.3.1.9, MetaCyc:6.3.1.9-RXN] +synonym: "glutathionylspermidine:glutathione ligase (ADP-forming)" EXACT [EC:6.3.1.9] +synonym: "TSR synthetase activity" EXACT [EC:6.3.1.9] +xref: EC:6.3.1.9 +xref: MetaCyc:6.3.1.9-RXN +xref: RHEA:21532 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0047480 +name: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP." [EC:6.3.2.10, MetaCyc:6.3.2.10-RXN] +comment: Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766). +synonym: "MurF synthetase activity" RELATED [EC:6.3.2.10] +synonym: "UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-MurNAc-pentapeptide synthetase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity" EXACT [] +synonym: "UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] +synonym: "UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity" EXACT [] +synonym: "UDPacetylmuramoylpentapeptide synthetase activity" EXACT [EC:6.3.2.10] +synonym: "uridine diphosphoacetylmuramoylpentapeptide synthetase activity" EXACT [EC:6.3.2.10] +xref: EC:6.3.2.10 +xref: MetaCyc:6.3.2.10-RXN +xref: RHEA:16085 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047481 +name: D-alanine-alanyl-poly(glycerolphosphate) ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP." [EC:6.3.2.16, MetaCyc:6.3.2.16-RXN] +synonym: "D-alanine-membrane acceptor-ligase activity" EXACT [EC:6.3.2.16] +synonym: "D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)" EXACT [EC:6.3.2.16] +synonym: "D-alanine:membrane-acceptor ligase activity" EXACT [EC:6.3.2.16] +synonym: "D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity" EXACT [EC:6.3.2.16] +synonym: "D-alanyl-poly(phosphoglycerol) synthetase activity" EXACT [EC:6.3.2.16] +synonym: "D-alanylalanylpoly(phosphoglycerol) synthetase activity" EXACT [EC:6.3.2.16] +xref: EC:6.3.2.16 +xref: MetaCyc:6.3.2.16-RXN +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047482 +name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine." [EC:6.3.2.7, RHEA:17969] +synonym: "L-lysine-adding enzyme activity" RELATED [EC:6.3.2.7] +synonym: "MurE synthetase activity" RELATED [EC:6.3.2.7] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.7] +synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity" EXACT [EC:6.3.2.7] +synonym: "UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity" EXACT [EC:6.3.2.7] +synonym: "uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity" EXACT [EC:6.3.2.7] +xref: EC:6.3.2.7 +xref: KEGG_REACTION:R02786 +xref: MetaCyc:6.3.2.7-RXN +xref: RHEA:17969 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047483 +name: imidazoleacetate-phosphoribosyldiphosphate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate." [EC:6.3.4.8, RHEA:16485] +synonym: "5-phosphoribosylimidazoleacetate synthetase activity" EXACT [EC:6.3.4.8] +synonym: "imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming)" EXACT [EC:6.3.4.8] +xref: EC:6.3.4.8 +xref: KEGG_REACTION:R04068 +xref: MetaCyc:6.3.4.8-RXN +xref: RHEA:16485 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0047484 +name: regulation of response to osmotic stress +namespace: biological_process +def: "Any process that modulates the rate or extent of the response to osmotic stress." [GOC:ai] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006970 ! response to osmotic stress +relationship: regulates GO:0006970 ! response to osmotic stress + +[Term] +id: GO:0047485 +name: protein N-terminus binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue." [ISBN:0198506732] +synonym: "amino-terminal binding" RELATED [GOC:jsg] +synonym: "amino-terminus binding" RELATED [GOC:jsg] +synonym: "N-terminal binding" EXACT [] +synonym: "N-terminal end binding" EXACT [GOC:jsg] +synonym: "NH2-terminal binding" NARROW [GOC:jsg] +synonym: "NH2-terminus binding" NARROW [GOC:jsg] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0047486 +name: chondroitin ABC lyase activity +namespace: molecular_function +def: "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups." [GOC:hjd] +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047487 +name: oligogalacturonide lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate." [EC:4.2.2.6, MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN] +synonym: "OGTE" RELATED [EC:4.2.2.6] +synonym: "oligogalacturonate lyase activity" EXACT [EC:4.2.2.6] +synonym: "unsaturated oligogalacturonate transeliminase activity" EXACT [EC:4.2.2.6] +xref: EC:4.2.2.6 +xref: MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN +xref: RHEA:20269 +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047488 +name: heparin lyase activity +namespace: molecular_function +def: "Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.7, MetaCyc:4.2.2.7-RXN] +synonym: "heparan sulfate lyase activity" RELATED [] +synonym: "heparin eliminase activity" RELATED [EC:4.2.2.7] +synonym: "heparinase activity" EXACT [EC:4.2.2.7] +xref: EC:4.2.2.7 +xref: MetaCyc:4.2.2.7-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047489 +name: pectate disaccharide-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin." [EC:4.2.2.9] +synonym: "(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity" EXACT [EC:4.2.2.9] +synonym: "exo-PATE" RELATED [EC:4.2.2.9] +synonym: "Exo-PATE activity" EXACT [EC:4.2.2.9] +synonym: "exo-PGL" RELATED [EC:4.2.2.9] +synonym: "Exo-PGL activity" EXACT [EC:4.2.2.9] +synonym: "exopectate lyase activity" EXACT [EC:4.2.2.9] +synonym: "exopectic acid transeliminase activity" EXACT [EC:4.2.2.9] +synonym: "exopolygalacturonate lyase activity" EXACT [EC:4.2.2.9] +synonym: "exopolygalacturonic acid-trans-eliminase activity" EXACT [EC:4.2.2.9] +synonym: "PATE activity" EXACT [EC:4.2.2.9] +synonym: "pectate exo-lyase activity" EXACT [EC:4.2.2.9] +xref: EC:4.2.2.9 +xref: MetaCyc:4.2.2.9-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047490 +name: pectin lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.10] +synonym: "(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity" EXACT [EC:4.2.2.10] +synonym: "endo-pectin lyase activity" EXACT [EC:4.2.2.10] +synonym: "pectin methyltranseliminase activity" EXACT [EC:4.2.2.10] +synonym: "pectin trans-eliminase activity" BROAD [EC:4.2.2.10] +synonym: "pectolyase activity" EXACT [EC:4.2.2.10] +synonym: "PL activity" EXACT [EC:4.2.2.10] +synonym: "PMGL activity" EXACT [EC:4.2.2.10] +synonym: "PNL activity" EXACT [EC:4.2.2.10] +synonym: "polymethylgalacturonic transeliminase activity" EXACT [EC:4.2.2.10] +xref: EC:4.2.2.10 +xref: MetaCyc:4.2.2.10-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047491 +name: poly(alpha-L-guluronate) lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.11] +synonym: "alginase II activity" RELATED [EC:4.2.2.11] +synonym: "guluronate lyase activity" EXACT [EC:4.2.2.11] +synonym: "L-guluronan lyase activity" EXACT [EC:4.2.2.11] +synonym: "L-guluronate lyase activity" EXACT [EC:4.2.2.11] +synonym: "poly(alpha-L-1,4-guluronide) exo-lyase activity" EXACT [EC:4.2.2.11] +synonym: "poly-alpha-L-guluronate lyase activity" EXACT [EC:4.2.2.11] +synonym: "polyguluronate-specific alginate lyase activity" EXACT [EC:4.2.2.11] +xref: EC:4.2.2.11 +xref: MetaCyc:4.2.2.11-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047492 +name: xanthan lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain." [EC:4.2.2.12] +xref: EC:4.2.2.12 +xref: MetaCyc:4.2.2.12-RXN +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0047493 +name: ceramide cholinephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin." [EC:2.7.8.3, RHEA:16273] +synonym: "CDP-choline:N-acylsphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.3] +synonym: "phosphorylcholine-ceramide transferase activity" EXACT [EC:2.7.8.3] +xref: EC:2.7.8.3 +xref: KEGG_REACTION:R01891 +xref: MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN +xref: RHEA:16273 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047494 +name: serine-phosphoethanolamine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+)." [EC:2.7.8.4, RHEA:22656] +synonym: "CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity" EXACT [EC:2.7.8.4] +synonym: "serine ethanolamine phosphate synthetase activity" EXACT [EC:2.7.8.4] +synonym: "serine ethanolamine phosphodiester synthase activity" EXACT [EC:2.7.8.4] +synonym: "serine ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.4] +synonym: "serine-phosphinico-ethanolamine synthase activity" EXACT [EC:2.7.8.4] +synonym: "serinephosphoethanolamine synthase activity" EXACT [EC:2.7.8.4] +xref: EC:2.7.8.4 +xref: KEGG_REACTION:R02563 +xref: MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN +xref: RHEA:22656 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047495 +name: membrane-oligosaccharide glycerophosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another." [EC:2.7.8.21] +synonym: "membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity" EXACT [EC:2.7.8.21] +synonym: "periplasmic phosphoglycerotransferase activity" NARROW [EC:2.7.8.21] +synonym: "phosphoglycerol cyclase activity" RELATED [EC:2.7.8.21] +xref: EC:2.7.8.21 +xref: MetaCyc:2.7.8.21-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0047496 +name: vesicle transport along microtubule +namespace: biological_process +def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl] +synonym: "microtubule-based vesicle localization" EXACT [GOC:rl] +is_a: GO:0072384 ! organelle transport along microtubule +is_a: GO:0099518 ! vesicle cytoskeletal trafficking + +[Term] +id: GO:0047497 +name: mitochondrion transport along microtubule +namespace: biological_process +def: "The directed movement of a mitochondrion along a microtubule, mediated by motor proteins." [GOC:ecd] +synonym: "mitochondrial migration along microtubule" EXACT [] +synonym: "mitochondrial transport along microtubule" EXACT [] +is_a: GO:0034643 ! establishment of mitochondrion localization, microtubule-mediated +is_a: GO:0072384 ! organelle transport along microtubule + +[Term] +id: GO:0047498 +name: calcium-dependent phospholipase A2 activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+." [EC:3.1.1.4] +synonym: "calcium-dependent cytosolic phospholipase A2 activity" NARROW [] +synonym: "calcium-dependent secreted phospholipase A2 activity" NARROW [] +xref: Reactome:R-HSA-111883 "Hydrolysis of phosphatidylcholine" +is_a: GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0047499 +name: calcium-independent phospholipase A2 activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+." [EC:3.1.1.4] +subset: goslim_chembl +synonym: "calcium-independent cytosolic phospholipase A2 activity" NARROW [] +xref: Reactome:R-HSA-8952251 "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)" +is_a: GO:0004623 ! phospholipase A2 activity + +[Term] +id: GO:0047500 +name: (+)-borneol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH." [EC:1.1.1.198, RHEA:17329] +synonym: "(+)-borneol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.198] +synonym: "bicyclic monoterpenol dehydrogenase activity" EXACT [EC:1.1.1.198] +xref: EC:1.1.1.198 +xref: KEGG_REACTION:R02944 +xref: MetaCyc:+-BORNEOL-DEHYDROGENASE-RXN +xref: RHEA:17329 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047501 +name: (+)-neomenthol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH." [EC:1.1.1.208, RHEA:23812] +synonym: "(+)-neomenthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.208] +synonym: "monoterpenoid dehydrogenase activity" BROAD [EC:1.1.1.208] +xref: EC:1.1.1.208 +xref: KEGG_REACTION:R02548 +xref: MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN +xref: RHEA:23812 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047502 +name: (+)-sabinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH." [EC:1.1.1.228, RHEA:18329] +synonym: "(+)-cis-sabinol dehydrogenase activity" EXACT [EC:1.1.1.228] +synonym: "(+)-cis-sabinol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.228] +xref: EC:1.1.1.228 +xref: KEGG_REACTION:R03745 +xref: MetaCyc:+-SABINOL-DEHYDROGENASE-RXN +xref: RHEA:18329 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047503 +name: (-)-borneol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH." [EC:1.1.1.227, RHEA:22128] +synonym: "(-)-borneol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.227] +xref: EC:1.1.1.227 +xref: KEGG_REACTION:R02945 +xref: MetaCyc:--BORNEOL-DEHYDROGENASE-RXN +xref: RHEA:22128 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047504 +name: (-)-menthol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH." [EC:1.1.1.207, RHEA:13917] +synonym: "(-)-menthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.207] +synonym: "monoterpenoid dehydrogenase activity" BROAD [EC:1.1.1.207] +xref: EC:1.1.1.207 +xref: KEGG_REACTION:R02177 +xref: MetaCyc:--MENTHOL-DEHYDROGENASE-RXN +xref: RHEA:13917 +xref: UM-BBD_reactionID:r1182 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047505 +name: (-)-menthol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+)." [EC:1.14.13.46, RHEA:11648] +synonym: "(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.13.46] +synonym: "l-menthol monooxygenase activity" EXACT [EC:1.14.13.46] +xref: EC:1.14.13.46 +xref: KEGG_REACTION:R02178 +xref: MetaCyc:--MENTHOL-MONOOXYGENASE-RXN +xref: RHEA:11648 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047506 +name: (deoxy)adenylate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dAMP = ADP + dADP." [EC:2.7.4.11, MetaCyc:DEOXYADENYLATE-KINASE-RXN] +synonym: "ATP:(d)AMP phosphotransferase activity" EXACT [EC:2.7.4.11] +xref: EC:2.7.4.11 +xref: MetaCyc:DEOXYADENYLATE-KINASE-RXN +xref: RHEA:23100 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0047507 +name: (deoxy)nucleoside-phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate." [EC:2.7.4.13, MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN] +synonym: "ATP:deoxynucleoside-phosphate phosphotransferase activity" EXACT [EC:2.7.4.13] +synonym: "deoxynucleoside monophosphate kinase activity" EXACT [EC:2.7.4.13] +synonym: "deoxynucleoside-5'-monophosphate kinase activity" EXACT [EC:2.7.4.13] +synonym: "deoxyribonucleoside monophosphokinase activity" EXACT [EC:2.7.4.13] +xref: EC:2.7.4.13 +xref: MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN +xref: RHEA:11216 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity + +[Term] +id: GO:0047508 +name: (R)-2-methylmalate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O." [EC:4.2.1.35, RHEA:22332] +synonym: "(-)-citramalate hydro-lyase activity" EXACT [EC:4.2.1.35] +synonym: "(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)" EXACT [EC:4.2.1.35] +synonym: "(R)-2-methylmalate hydro-lyase activity" EXACT [EC:4.2.1.35] +synonym: "citraconase activity" EXACT [EC:4.2.1.35] +synonym: "citraconate hydratase activity" EXACT [EC:4.2.1.35] +synonym: "citramalate hydro-lyase activity" EXACT [EC:4.2.1.35] +xref: EC:4.2.1.35 +xref: KEGG_REACTION:R03896 +xref: MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN +xref: RHEA:22332 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047509 +name: (R)-dehydropantoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH." [EC:1.2.1.33, RHEA:19349] +synonym: "(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.2.1.33] +synonym: "D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity" EXACT [EC:1.2.1.33] +synonym: "D-aldopantoate dehydrogenase activity" EXACT [EC:1.2.1.33] +xref: EC:1.2.1.33 +xref: KEGG_REACTION:R03198 +xref: MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN +xref: RHEA:19349 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047510 +name: (S)-2-methylmalate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-citramalate = H(2)O + mesaconate." [EC:4.2.1.34, RHEA:13529] +synonym: "(+)-citramalate hydro-lyase activity" EXACT [EC:4.2.1.34] +synonym: "(+)-citramalic hydro-lyase activity" EXACT [EC:4.2.1.34] +synonym: "(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)" EXACT [EC:4.2.1.34] +synonym: "(S)-2-methylmalate hydro-lyase activity" EXACT [EC:4.2.1.34] +synonym: "citramalate dehydratase activity" EXACT [EC:4.2.1.34] +synonym: "L-citramalate hydrolase activity" EXACT [EC:4.2.1.34] +synonym: "mesaconase activity" EXACT [EC:4.2.1.34] +synonym: "mesaconate hydratase activity" EXACT [EC:4.2.1.34] +synonym: "mesaconate mesaconase activity" EXACT [EC:4.2.1.34] +xref: EC:4.2.1.34 +xref: KEGG_REACTION:R03693 +xref: MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN +xref: RHEA:13529 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047511 +name: (S)-methylmalonyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate." [EC:3.1.2.17, RHEA:17345] +synonym: "D-methylmalonyl-coenzyme A hydrolase activity" EXACT [EC:3.1.2.17] +xref: EC:3.1.2.17 +xref: KEGG_REACTION:R02764 +xref: MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN +xref: RHEA:17345 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0047512 +name: (S,S)-butanediol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH." [EC:1.1.1.76, RHEA:12184] +synonym: "(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.76] +synonym: "L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)" EXACT [EC:1.1.1.76] +synonym: "L-BDH" RELATED [EC:1.1.1.76] +synonym: "L-butanediol dehydrogenase activity" EXACT [EC:1.1.1.76] +xref: EC:1.1.1.76 +xref: KEGG_REACTION:R03707 +xref: MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN +xref: RHEA:12184 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047513 +name: 1,2-alpha-L-fucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside." [EC:3.2.1.63, MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN] +synonym: "2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity" EXACT [EC:3.2.1.63] +synonym: "almond emulsin fucosidase activity" EXACT [EC:3.2.1.63] +synonym: "almond emulsin fucosidase II activity" NARROW [EC:3.2.1.63] +synonym: "alpha-(1->2)-L-fucosidase activity" EXACT [EC:3.2.1.63] +xref: EC:3.2.1.63 +xref: MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN +xref: RHEA:10816 +is_a: GO:0004560 ! alpha-L-fucosidase activity + +[Term] +id: GO:0047514 +name: 1,3-beta-D-glucan phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin." [EC:2.4.1.97, MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN] +synonym: "1,3-beta-D-glucan:orthophosphate glucosyltransferase activity" EXACT [EC:2.4.1.97] +synonym: "1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.97] +synonym: "1,3-beta-glucan phosphorylase activity" EXACT [] +synonym: "laminarin phosphorylase activity" RELATED [EC:2.4.1.97] +synonym: "laminarin phosphoryltransferase activity" EXACT [EC:2.4.1.97] +xref: EC:2.4.1.97 +xref: MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047515 +name: 1,3-beta-oligoglucan phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate." [EC:2.4.1.30, MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN] +synonym: "1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.30] +synonym: "beta-1,3-oligoglucan phosphorylase activity" EXACT [EC:2.4.1.30] +synonym: "beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity" EXACT [EC:2.4.1.30] +xref: EC:2.4.1.30 +xref: MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047516 +name: 1,3-propanediol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+." [EC:1.1.1.202, MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN] +synonym: "1,3-PD:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.202] +synonym: "1,3-propanediol oxidoreductase activity" EXACT [EC:1.1.1.202] +synonym: "1,3-propanediol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.202] +synonym: "3-hydroxypropionaldehyde reductase activity" EXACT [EC:1.1.1.202] +synonym: "propane-1,3-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.202] +xref: EC:1.1.1.202 +xref: MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN +xref: RHEA:23188 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047517 +name: 1,4-beta-D-xylan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1)." [EC:2.4.2.24, MetaCyc:1\,4-BETA-D-XYLAN-SYNTHASE-RXN] +synonym: "1,4-beta-xylan synthase activity" EXACT [EC:2.4.2.24] +synonym: "UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.24] +synonym: "uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity" EXACT [EC:2.4.2.24] +synonym: "xylan synthase activity" EXACT [EC:2.4.2.24] +synonym: "xylan synthetase activity" EXACT [EC:2.4.2.24] +xref: EC:2.4.2.24 +xref: MetaCyc:RXN-9104 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047518 +name: 1-methyladenosine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose." [EC:3.2.2.13, RHEA:12865] +synonym: "1-methyladenosine hydrolase activity" EXACT [EC:3.2.2.13] +synonym: "1-methyladenosine ribohydrolase activity" EXACT [EC:3.2.2.13] +xref: EC:3.2.2.13 +xref: KEGG_REACTION:R03885 +xref: MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN +xref: RHEA:12865 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0047519 +name: quinate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol." [RHEA:23672] +synonym: "NAD(P)-independent quinate dehydrogenase activity" EXACT [EC:1.1.5.8] +synonym: "quinate:pyrroloquinoline-quinone 5-oxidoreductase activity" EXACT [EC:1.1.5.8] +synonym: "quinate:quinone 3-oxidoreductase activity" EXACT systematic_synonym [EC:1.1.5.8] +xref: EC:1.1.5.8 +xref: KEGG_REACTION:R01873 +xref: MetaCyc:1.1.99.25-RXN +xref: RHEA:23672 +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0047520 +name: 11-cis-retinyl-palmitate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate." [EC:3.1.1.63, RHEA:19697] +synonym: "11-cis-retinol palmitate esterase activity" EXACT [EC:3.1.1.63] +synonym: "11-cis-retinyl-palmitate acylhydrolase activity" EXACT [EC:3.1.1.63] +synonym: "RPH" RELATED [EC:3.1.1.63] +xref: EC:3.1.1.63 +xref: KEGG_REACTION:R03049 +xref: MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN +xref: Reactome:R-HSA-2465941 "A REH hydrolyses 11cRE to 11cROL" +xref: RHEA:19697 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0047521 +name: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH." [EC:1.1.1.238, RHEA:21424] +synonym: "12-beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.238] +synonym: "12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" BROAD [EC:1.1.1.238] +synonym: "12beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.238] +synonym: "12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity" BROAD [EC:1.1.1.238] +xref: EC:1.1.1.238 +xref: KEGG_REACTION:R03495 +xref: MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN +xref: RHEA:21424 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047522 +name: 15-oxoprostaglandin 13-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+." [EC:1.3.1.48, KEGG_REACTION:R04556, KEGG_REACTION:R04557, MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN] +comment: Note that this is the reverse of the reaction described in '13-prostaglandin reductase activity ; GO:0036132'. +synonym: "(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity" EXACT [EC:1.3.1.48] +xref: EC:1.3.1.48 +xref: KEGG_REACTION:R04556 +xref: KEGG_REACTION:R04557 +xref: MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047524 +name: 16-hydroxysteroid epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid." [EC:5.1.99.2, MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN] +synonym: "16-hydroxysteroid 16-epimerase activity" EXACT [EC:5.1.99.2] +xref: EC:5.1.99.2 +xref: MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0047525 +name: 2'-hydroxydaidzein reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+." [EC:1.3.1.51, MetaCyc:2'-HYDROXYDAIDZEIN-REDUCTASE-RXN] +synonym: "2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] +synonym: "2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] +synonym: "2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] +synonym: "HDR activity" EXACT [EC:1.3.1.51] +synonym: "NADPH:2'-hydroxydaidzein oxidoreductase activity" EXACT [EC:1.3.1.51] +xref: EC:1.3.1.51 +xref: MetaCyc:RXN-4502 +xref: RHEA:17145 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047526 +name: 2'-hydroxyisoflavone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+." [EC:1.3.1.45, MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN] +synonym: "2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity" EXACT [EC:1.3.1.45] +synonym: "isoflavone reductase activity" EXACT [EC:1.3.1.45] +synonym: "NADPH:2'-hydroxyisoflavone oxidoreductase activity" EXACT [EC:1.3.1.45] +synonym: "vestitone:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.45] +xref: EC:1.3.1.45 +xref: MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN +xref: RHEA:22560 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047527 +name: 2,3-dihydroxybenzoate-serine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine." [EC:6.3.2.14, MetaCyc:1\,3-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN] +synonym: "2,3-dihydroxybenzoate:L-serine ligase activity" EXACT [EC:6.3.2.14] +synonym: "2,3-dihydroxybenzoylserine synthetase activity" EXACT [EC:6.3.2.14] +synonym: "N-(2,3-dihydroxybenzoyl)-serine synthetase activity" EXACT [EC:6.3.2.14] +xref: EC:6.3.2.14 +xref: MetaCyc:23-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047528 +name: 2,3-dihydroxyindole 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+)." [EC:1.13.11.23, RHEA:19445] +synonym: "2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity" EXACT [EC:1.13.11.23] +xref: EC:1.13.11.23 +xref: KEGG_REACTION:R00983 +xref: MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN +xref: RHEA:19445 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047529 +name: 2,3-dimethylmalate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate." [EC:4.1.3.32, RHEA:10472] +synonym: "(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)" EXACT [EC:4.1.3.32] +synonym: "(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity" EXACT [EC:4.1.3.32] +synonym: "2,3-dimethylmalate pyruvate-lyase activity" EXACT [EC:4.1.3.32] +xref: EC:4.1.3.32 +xref: KEGG_REACTION:R01355 +xref: MetaCyc:23-DIMETHYLMALATE-LYASE-RXN +xref: RHEA:10472 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047530 +name: 2,4-diaminopentanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+." [EC:1.4.1.12, MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN] +synonym: "2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.12] +synonym: "2,4-diaminopentanoic acid C4 dehydrogenase activity" EXACT [EC:1.4.1.12] +xref: EC:1.4.1.12 +xref: MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047531 +name: 2,5-diaminovalerate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate." [EC:2.6.1.8, RHEA:16017] +synonym: "2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.8] +synonym: "2,5-diaminovalerate aminotransferase activity" EXACT [] +synonym: "diamino acid aminotransferase activity" EXACT [EC:2.6.1.8] +synonym: "diamino-acid aminotransferase activity" RELATED [EC:2.6.1.8] +synonym: "diamino-acid transaminase activity" EXACT [EC:2.6.1.8] +xref: EC:2.6.1.8 +xref: KEGG_REACTION:R03248 +xref: MetaCyc:25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN +xref: RHEA:16017 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047532 +name: 2,5-dioxopiperazine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine." [EC:3.5.2.13, RHEA:21808] +synonym: "2,5-dioxopiperazine amidohydrolase activity" EXACT [EC:3.5.2.13] +synonym: "cyclo(Gly-Gly) hydrolase activity" EXACT [EC:3.5.2.13] +synonym: "cyclo(glycylglycine) hydrolase activity" EXACT [EC:3.5.2.13] +xref: EC:3.5.2.13 +xref: KEGG_REACTION:R03810 +xref: MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN +xref: RHEA:21808 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0047533 +name: 2,5-dioxovalerate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+." [EC:1.2.1.26, MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN] +synonym: "2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity" EXACT [EC:1.2.1.26] +synonym: "2-oxoglutarate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.26] +synonym: "alpha-ketoglutaric semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.26] +xref: EC:1.2.1.26 +xref: MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN +xref: RHEA:11296 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047534 +name: 2-acetolactate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate." [EC:5.4.99.3, MetaCyc:2-ACETOLACTATE-MUTASE-RXN] +synonym: "2-acetolactate methylmutase activity" EXACT [EC:5.4.99.3] +synonym: "acetohydroxy acid isomerase activity" BROAD [EC:5.4.99.3] +synonym: "acetolactate mutase activity" EXACT [EC:5.4.99.3] +xref: EC:5.4.99.3 +xref: MetaCyc:2-ACETOLACTATE-MUTASE-RXN +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047535 +name: 2-alkyn-1-ol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH." [EC:1.1.1.165, RHEA:19101] +synonym: "2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.165] +xref: EC:1.1.1.165 +xref: KEGG_REACTION:R03963 +xref: MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN +xref: RHEA:19101 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047536 +name: 2-aminoadipate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate." [EC:2.6.1.39, RHEA:12601] +synonym: "2-aminoadipate aminotransferase activity" EXACT [] +synonym: "2-aminoadipic aminotransferase activity" EXACT [EC:2.6.1.39] +synonym: "alpha-aminoadipate aminotransferase activity" EXACT [EC:2.6.1.39] +synonym: "glutamate-alpha-ketoadipate transaminase activity" EXACT [EC:2.6.1.39] +synonym: "glutamic-ketoadipic transaminase activity" EXACT [EC:2.6.1.39] +synonym: "L-2-aminoadipate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.39] +xref: EC:2.6.1.39 +xref: KEGG_REACTION:R01939 +xref: MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-508561 "alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate" +xref: Reactome:R-HSA-70952 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate" +xref: RHEA:12601 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047537 +name: 2-aminohexanoate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate." [EC:2.6.1.67, MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN] +synonym: "2-aminohexanoate aminotransferase activity" EXACT [] +synonym: "L-2-aminohexanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.67] +synonym: "leucine L-norleucine: 2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.67] +synonym: "norleucine (leucine) aminotransferase activity" EXACT [EC:2.6.1.67] +synonym: "norleucine aminotransferase activity" EXACT [EC:2.6.1.67] +synonym: "norleucine transaminase activity" EXACT [EC:2.6.1.67] +xref: EC:2.6.1.67 +xref: MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN +xref: RHEA:23600 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047538 +name: 2-carboxy-D-arabinitol-1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate." [EC:3.1.3.63, RHEA:17837] +synonym: "2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.63] +synonym: "2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.63] +synonym: "2-carboxyarabinitol 1-phosphatase activity" EXACT [EC:3.1.3.63] +xref: EC:3.1.3.63 +xref: KEGG_REACTION:R04167 +xref: MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN +xref: RHEA:17837 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047539 +name: 2-deoxyglucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol." [EC:3.2.1.112, MetaCyc:2-DEOXYGLUCOSIDASE-RXN] +synonym: "2-deoxy-alpha-D-glucosidase activity" EXACT [EC:3.2.1.112] +synonym: "2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity" EXACT [EC:3.2.1.112] +synonym: "2-deoxy-alpha-glucosidase activity" EXACT [EC:3.2.1.112] +xref: EC:3.2.1.112 +xref: MetaCyc:2-DEOXYGLUCOSIDASE-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0047540 +name: 2-enoate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+." [EC:1.3.1.31, MetaCyc:2-ENOATE-REDUCTASE-RXN] +synonym: "butanoate:NAD+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.31] +synonym: "enoate reductase activity" EXACT [EC:1.3.1.31] +xref: EC:1.3.1.31 +xref: MetaCyc:2-ENOATE-REDUCTASE-RXN +xref: RHEA:10200 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047541 +name: 2-furoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+)." [EC:6.2.1.31, RHEA:19269] +synonym: "2-furoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.31] +synonym: "2-furoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.31] +xref: EC:6.2.1.31 +xref: KEGG_REACTION:R02986 +xref: MetaCyc:2-FUROATE--COA-LIGASE-RXN +xref: RHEA:19269 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047542 +name: 2-furoyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+)." [EC:1.3.99.8, RHEA:21480] +synonym: "2-furoyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.8] +synonym: "2-furoyl coenzyme A hydroxylase activity" EXACT [EC:1.3.99.8] +synonym: "2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.8] +synonym: "2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.8] +synonym: "furoyl-CoA hydroxylase activity" EXACT [EC:1.3.99.8] +xref: EC:1.3.99.8 +xref: KEGG_REACTION:R02987 +xref: MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN +xref: RHEA:21480 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047543 +name: 2-hexadecenal reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH." [EC:1.3.1.27, RHEA:12444] +synonym: "hexadecanal: NADP+ oxidoreductase activity" EXACT [EC:1.3.1.27] +synonym: "hexadecanal:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.27] +xref: EC:1.3.1.27 +xref: KEGG_REACTION:R02463 +xref: MetaCyc:2-HEXADECENAL-REDUCTASE-RXN +xref: RHEA:12444 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047544 +name: 2-hydroxybiphenyl 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+)." [EC:1.14.13.44, RHEA:11996] +synonym: "2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.44] +xref: EC:1.14.13.44 +xref: KEGG_REACTION:R03964 +xref: MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN +xref: RHEA:11996 +xref: UM-BBD_reactionID:r1423 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047545 +name: 2-hydroxyglutarate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor." [EC:1.1.99.2, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN] +synonym: "(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase" EXACT [EC:1.1.99.2] +synonym: "(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase" EXACT [EC:1.1.99.2] +synonym: "alpha-hydroxyglutarate dehydrogenase (NAD+ specific)" NARROW [EC:1.1.99.2] +synonym: "alpha-hydroxyglutarate dehydrogenase activity" EXACT [EC:1.1.99.2] +synonym: "alpha-hydroxyglutarate oxidoreductase activity" EXACT [EC:1.1.99.2] +synonym: "hydroxyglutaric dehydrogenase activity" EXACT [EC:1.1.99.2] +synonym: "L-alpha-hydroxyglutarate dehydrogenase activity" EXACT [EC:1.1.99.2] +synonym: "L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase" NARROW [EC:1.1.99.2] +xref: EC:1.1.99.2 +xref: MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-880050 "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2" +xref: RHEA:21252 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047546 +name: 2-hydroxypyridine 5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O." [EC:1.14.99.26, RHEA:16973] +synonym: "2-hydroxypyridine oxygenase activity" EXACT [EC:1.14.99.26] +synonym: "2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.99.26] +xref: EC:1.14.99.26 +xref: KEGG_REACTION:R03206 +xref: MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN +xref: RHEA:16973 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0047547 +name: 2-methylcitrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O." [EC:4.2.1.79, RHEA:17725] +synonym: "(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]" RELATED [EC:4.2.1.79] +synonym: "2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.79] +synonym: "2-methylcitrate hydro-lyase activity" EXACT [EC:4.2.1.79] +synonym: "prpD" RELATED [EC:4.2.1.79] +xref: EC:4.2.1.79 +xref: KEGG_REACTION:R04424 +xref: MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN +xref: RHEA:17725 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047548 +name: 2-methyleneglutarate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate." [EC:5.4.99.4, RHEA:13793] +synonym: "2-methyleneglutarate carboxy-methylenemethylmutase activity" EXACT [EC:5.4.99.4] +synonym: "alpha-methyleneglutarate mutase activity" EXACT [EC:5.4.99.4] +xref: EC:5.4.99.4 +xref: KEGG_REACTION:R03908 +xref: MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN +xref: RHEA:13793 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047549 +name: 2-nitrophenol 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite." [EC:1.14.13.31, RHEA:19457] +synonym: "2-nitrophenol oxygenase activity" EXACT [EC:1.14.13.31] +synonym: "2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)" EXACT [EC:1.14.13.31] +synonym: "nitrophenol oxygenase activity" BROAD [EC:1.14.13.31] +xref: EC:1.14.13.31 +xref: KEGG_REACTION:R00828 +xref: MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN +xref: RHEA:19457 +xref: UM-BBD_reactionID:r1494 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047550 +name: 2-oxoadipate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH." [EC:1.1.1.172, RHEA:14793] +synonym: "2-hydroxyadipate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.172] +synonym: "2-ketoadipate reductase activity" EXACT [EC:1.1.1.172] +synonym: "alpha-ketoadipate reductase activity" EXACT [EC:1.1.1.172] +xref: EC:1.1.1.172 +xref: KEGG_REACTION:R01932 +xref: MetaCyc:2-OXOADIPATE-REDUCTASE-RXN +xref: RHEA:14793 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047551 +name: 2-oxoaldehyde dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+." [EC:1.2.1.23, MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN] +synonym: "2-ketoaldehyde dehydrogenase" BROAD [EC:1.2.1.23] +synonym: "2-oxoaldehyde dehydrogenase (NAD+)" EXACT [EC:1.2.1.23] +synonym: "2-oxoaldehyde:NAD+ 2-oxidoreductase activity" EXACT [EC:1.2.1.23] +synonym: "alpha-ketoaldehyde dehydrogenase activity" BROAD [EC:1.2.1.23] +synonym: "methylglyoxal dehydrogenase activity" BROAD [EC:1.2.1.23] +synonym: "NAD-dependent alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.23] +synonym: "NAD-linked alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.23] +xref: EC:1.2.1.23 +xref: MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN +xref: RHEA:22276 +xref: Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+) +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0047552 +name: 2-oxoaldehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+." [EC:1.2.1.49, MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN] +synonym: "2-ketoaldehyde dehydrogenase" BROAD [EC:1.2.1.49] +synonym: "2-oxoaldehyde:NADP+ 2-oxidoreductase activity" EXACT [EC:1.2.1.49] +synonym: "alpha-ketoaldehyde dehydrogenase activity" BROAD [EC:1.2.1.49] +synonym: "methylglyoxal dehydrogenase activity" BROAD [EC:1.2.1.49] +synonym: "NADP-dependent alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.49] +synonym: "NADP-linked alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.49] +xref: EC:1.2.1.49 +xref: MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:18129 +is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity + +[Term] +id: GO:0047553 +name: 2-oxoglutarate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.3, MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN] +synonym: "2-ketoglutarate ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] +synonym: "2-oxoglutarate ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] +synonym: "2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)" EXACT [EC:1.2.7.3] +synonym: "2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating)" EXACT [EC:1.2.7.3] +synonym: "2-oxoglutarate:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] +synonym: "alpha-ketoglutarate synthase activity" EXACT [EC:1.2.7.3] +synonym: "alpha-ketoglutarate-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] +synonym: "KGOR activity" EXACT [EC:1.2.7.3] +xref: EC:1.2.7.3 +xref: MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN +is_a: GO:0016625 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0047554 +name: 2-pyrone-4,6-dicarboxylate lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+)." [EC:3.1.1.57, RHEA:10644] +synonym: "2-pyrone-4,6-dicarboxylate lactonohydrolase activity" EXACT [EC:3.1.1.57] +xref: EC:3.1.1.57 +xref: KEGG_REACTION:R04277 +xref: MetaCyc:RXN-2462 +xref: RHEA:10644 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047555 +name: 3',5'-cyclic-GMP phosphodiesterase activity +namespace: molecular_function +alt_id: GO:0004116 +def: "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate." [EC:3.1.4.35, MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN] +synonym: "3',5' cyclic-GMP phosphodiesterase activity" EXACT [] +synonym: "3',5'-cyclic-GMP 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.35] +synonym: "cGMP phosphodiesterase activity" EXACT [] +synonym: "cGMP-PDE" RELATED [EC:3.1.4.35] +synonym: "cGMP-specific phosphodiesterase activity" EXACT [] +synonym: "cyclic 3',5'-GMP phosphodiesterase activity" EXACT [EC:3.1.4.35] +synonym: "cyclic GMP phosphodiesterase activity" EXACT [] +synonym: "cyclic guanosine 3',5'-monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.35] +synonym: "cyclic guanosine 3',5'-phosphate phosphodiesterase activity" EXACT [EC:3.1.4.35] +synonym: "guanosine cyclic 3',5'-phosphate phosphodiesterase activity" EXACT [] +xref: EC:3.1.4.35 +xref: MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN +xref: Reactome:R-HSA-4086392 "PDE6 hydrolyses cGMP to GMP" +xref: Reactome:R-HSA-418456 "cGMP is degraded by PDEs" +xref: Reactome:R-HSA-74059 "PDE6 hydrolyses cGMP to GMP" +xref: RHEA:16957 +is_a: GO:0004114 ! 3',5'-cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0047556 +name: 3,4-dihydroxyphthalate decarboxylase activity +namespace: molecular_function +alt_id: GO:0034913 +def: "Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2)." [EC:4.1.1.69, RHEA:18601] +synonym: "3,4-dihydroxyphthalate 2-decarboxylase activity" EXACT [] +synonym: "3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)" EXACT [EC:4.1.1.69] +synonym: "3,4-dihydroxyphthalate carboxy-lyase activity" EXACT [EC:4.1.1.69] +xref: EC:4.1.1.69 +xref: KEGG_REACTION:R01634 +xref: MetaCyc:34-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN +xref: RHEA:18601 +xref: UM-BBD_reactionID:r1447 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047557 +name: 3-aci-nitropropanoate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite." [EC:1.7.3.5, RHEA:22372] +synonym: "3-aci-nitropropanoate:oxygen oxidoreductase activity" EXACT [EC:1.7.3.5] +synonym: "propionate-3-nitronate oxidase activity" EXACT [EC:1.7.3.5] +xref: EC:1.7.3.5 +xref: KEGG_REACTION:R01609 +xref: MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN +xref: RHEA:22372 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor + +[Term] +id: GO:0047558 +name: 3-cyanoalanine hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+)." [EC:4.2.1.65, RHEA:15385] +synonym: "beta-CNA nitrilase activity" EXACT [EC:4.2.1.65] +synonym: "beta-CNAla hydrolase activity" EXACT [EC:4.2.1.65] +synonym: "beta-cyanoalanine hydratase activity" EXACT [EC:4.2.1.65] +synonym: "beta-cyanoalanine hydrolase activity" EXACT [EC:4.2.1.65] +synonym: "L-asparagine hydro-lyase (3-cyanoalanine-forming)" EXACT [EC:4.2.1.65] +synonym: "L-asparagine hydro-lyase activity" EXACT [EC:4.2.1.65] +xref: EC:4.2.1.65 +xref: KEGG_REACTION:R01267 +xref: MetaCyc:3-CYANOALANINE-HYDRATASE-RXN +xref: RHEA:15385 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047559 +name: 3-dehydro-L-gulonate 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+." [EC:1.1.1.130, MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN] +synonym: "2,3-diketo-L-gulonate reductase activity" EXACT [EC:1.1.1.130] +synonym: "3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.130] +synonym: "3-keto-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.130] +synonym: "3-ketogulonate dehydrogenase activity" EXACT [EC:1.1.1.130] +xref: EC:1.1.1.130 +xref: MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047560 +name: 3-dehydrosphinganine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH." [EC:1.1.1.102, RHEA:22640] +synonym: "3-ketosphinganine reductase activity" EXACT [EC:1.1.1.102] +synonym: "3-oxosphinganine reductase activity" EXACT [EC:1.1.1.102] +synonym: "3-oxosphinganine:NADPH oxidoreductase activity" EXACT [EC:1.1.1.102] +synonym: "D-3-dehydrosphinganine reductase activity" EXACT [EC:1.1.1.102] +synonym: "D-3-oxosphinganine reductase activity" EXACT [EC:1.1.1.102] +synonym: "D-3-oxosphinganine:B-NADPH oxidoreductase activity" EXACT [EC:1.1.1.102] +synonym: "D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.102] +synonym: "DSR activity" EXACT [EC:1.1.1.102] +synonym: "KTS reductase activity" RELATED [EC:1.1.1.102] +xref: EC:1.1.1.102 +xref: KEGG_REACTION:R02978 +xref: MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN +xref: Reactome:R-HSA-428123 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+" +xref: RHEA:22640 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047561 +name: 3-hydroxyanthranilate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2)." [EC:1.10.3.5, RHEA:17245] +synonym: "3-hydroxyanthranilate:oxygen oxidoreductase activity" EXACT [EC:1.10.3.5] +synonym: "3-hydroxyanthranilic acid oxidase activity" EXACT [EC:1.10.3.5] +xref: EC:1.10.3.5 +xref: KEGG_REACTION:R02666 +xref: MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN +xref: RHEA:17245 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0047562 +name: 3-hydroxyaspartate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate." [EC:4.1.3.14, RHEA:14377] +synonym: "erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity" EXACT [EC:4.1.3.14] +synonym: "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)" EXACT [EC:4.1.3.14] +synonym: "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity" EXACT [EC:4.1.3.14] +synonym: "erythro-beta-hydroxyaspartate aldolase activity" EXACT [EC:4.1.3.14] +synonym: "erythro-beta-hydroxyaspartate glycine-lyase activity" EXACT [EC:4.1.3.14] +xref: EC:4.1.3.14 +xref: KEGG_REACTION:R00478 +xref: MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN +xref: RHEA:14377 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047563 +name: 3-hydroxybenzoate 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O." [EC:1.14.99.23, RHEA:14193] +synonym: "3-HBA-2-hydroxylase activity" EXACT [EC:1.14.99.23] +synonym: "3-hydroxybenzoate 2-hydroxylase activity" EXACT [] +synonym: "3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.99.23] +xref: EC:1.14.99.23 +xref: KEGG_REACTION:R01508 +xref: MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN +xref: RHEA:14193 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0047564 +name: 3-hydroxycyclohexanone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione." [EC:1.1.99.26, RHEA:15905] +synonym: "3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.26] +xref: EC:1.1.99.26 +xref: KEGG_REACTION:R03212 +xref: MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN +xref: RHEA:15905 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047565 +name: 3-hydroxypropionate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH." [EC:1.1.1.59, RHEA:13357] +synonym: "3-hydroxypropanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.59] +xref: EC:1.1.1.59 +xref: KEGG_REACTION:R01608 +xref: MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN +xref: RHEA:13357 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047566 +name: 3-ketovalidoxylamine C-N-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+)." [EC:4.3.3.1, RHEA:22768] +synonym: "3-ketovalidoxylamine A C-N-lyase activity" EXACT [EC:4.3.3.1] +synonym: "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming]" RELATED [EC:4.3.3.1] +synonym: "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity" EXACT [EC:4.3.3.1] +synonym: "p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity" EXACT [EC:4.3.3.1] +xref: EC:4.3.3.1 +xref: KEGG_REACTION:R04367 +xref: MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN +xref: RHEA:22768 +is_a: GO:0016843 ! amine-lyase activity + +[Term] +id: GO:0047567 +name: 3-methyleneoxindole reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH." [EC:1.3.1.17, RHEA:20257] +synonym: "3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.17] +synonym: "3-methyloxindole:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.17] +xref: EC:1.3.1.17 +xref: KEGG_REACTION:R03930 +xref: MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN +xref: RHEA:20257 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047568 +name: 3-oxo-5-beta-steroid 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor." [EC:1.3.99.6, MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN] +synonym: "3-oxo-5beta-steroid 4-dehydrogenase activity" EXACT [EC:1.3.99.6] +synonym: "3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity" EXACT [EC:1.3.99.6] +synonym: "3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity" EXACT [EC:1.3.99.6] +synonym: "delta4-3-ketosteroid 5-beta-reductase activity" EXACT [EC:1.3.99.6] +xref: EC:1.3.99.6 +xref: MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN +is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047569 +name: 3-oxoadipate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA." [EC:2.8.3.6, MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN] +synonym: "3-oxoadipate coenzyme A-transferase activity" EXACT [EC:2.8.3.6] +synonym: "3-oxoadipate succinyl-CoA transferase activity" EXACT [EC:2.8.3.6] +synonym: "beta-ketoadipate:succinyl-CoA transferase activity" EXACT [EC:2.8.3.6] +synonym: "succinyl-CoA:3-oxoadipate CoA-transferase activity" EXACT [EC:2.8.3.6] +xref: EC:2.8.3.6 +xref: MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN +xref: RHEA:12048 +xref: UM-BBD_reactionID:r1050 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047570 +name: 3-oxoadipate enol-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate." [EC:3.1.1.24, MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN] +synonym: "3-ketoadipate enol-lactonase activity" EXACT [EC:3.1.1.24] +synonym: "3-oxoadipic enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] +synonym: "4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity" EXACT [EC:3.1.1.24] +synonym: "beta-ketoadipate enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] +synonym: "beta-ketoadipic enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] +synonym: "carboxymethylbutenolide lactonase activity" EXACT [EC:3.1.1.24] +xref: EC:3.1.1.24 +xref: MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN +xref: RHEA:10184 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047571 +name: 3-oxosteroid 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor." [EC:1.3.99.4, MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN] +synonym: "1-ene-dehydrogenase activity" EXACT [EC:1.3.99.4] +synonym: "3-ketosteroid-1-en-dehydrogenase activity" EXACT [EC:1.3.99.4] +synonym: "3-ketosteroid-delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] +synonym: "3-oxosteroid delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] +synonym: "3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] +synonym: "3-oxosteroid:(acceptor) delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] +synonym: "3-oxosteroid:acceptor delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] +synonym: "4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity" EXACT [EC:1.3.99.4] +synonym: "delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] +synonym: "delta1-steroid reductase activity" EXACT [EC:1.3.99.4] +xref: EC:1.3.99.4 +xref: MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN +xref: UM-BBD_enzymeID:e0712 +is_a: GO:0033765 ! steroid dehydrogenase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047572 +name: 3-phosphoglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate." [EC:3.1.3.38, RHEA:12412] +synonym: "3-PGA phosphatase activity" EXACT [EC:3.1.3.38] +synonym: "D-3-phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.38] +synonym: "D-glycerate-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.38] +xref: EC:3.1.3.38 +xref: KEGG_REACTION:R01511 +xref: MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN +xref: RHEA:12412 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047573 +name: 4-acetamidobutyrate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate." [EC:3.5.1.63, MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN] +synonym: "4-acetamidobutanoate amidohydrolase activity" EXACT [EC:3.5.1.63] +xref: EC:3.5.1.63 +xref: MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN +xref: RHEA:15897 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0047574 +name: 4-acetamidobutyryl-CoA deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate." [EC:3.5.1.51, RHEA:22928] +synonym: "4-acetamidobutanoyl-CoA amidohydrolase activity" EXACT [EC:3.5.1.51] +synonym: "aminobutyryl-CoA thiolesterase activity" EXACT [EC:3.5.1.51] +synonym: "deacetylase-thiolesterase activity" EXACT [EC:3.5.1.51] +xref: EC:3.5.1.51 +xref: KEGG_REACTION:R04056 +xref: MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN +xref: RHEA:22928 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0047575 +name: 4-carboxymuconolactone decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2)." [EC:4.1.1.44, RHEA:23348] +synonym: "4-carboxymonolactone carboxy-lyase activity" EXACT [EC:4.1.1.44] +synonym: "4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)" EXACT [EC:4.1.1.44] +synonym: "4-carboxymuconolactone carboxy-lyase activity" EXACT [EC:4.1.1.44] +synonym: "gamma-4-carboxymuconolactone decarboxylase activity" EXACT [EC:4.1.1.44] +xref: EC:4.1.1.44 +xref: KEGG_REACTION:R03470 +xref: MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN +xref: RHEA:23348 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047576 +name: 4-chlorobenzoate dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+)." [EC:3.8.1.6, RHEA:23440] +synonym: "4-chlorobenzoate chlorohydrolase activity" EXACT [EC:3.8.1.6] +synonym: "halobenzoate dehalogenase activity" EXACT [EC:3.8.1.6] +xref: EC:3.8.1.6 +xref: KEGG_REACTION:R01307 +xref: MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN +xref: RHEA:23440 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0047577 +name: 4-hydroxybutyrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde." [EC:1.1.1.61, RHEA:23948] +synonym: "4-hydroxybutanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.61] +synonym: "gamma-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.61] +xref: EC:1.1.1.61 +xref: KEGG_REACTION:R01644 +xref: MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN +xref: RHEA:23948 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047578 +name: 4-hydroxyglutamate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate." [EC:2.6.1.23, MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN] +synonym: "4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.23] +synonym: "4-hydroxyglutamate aminotransferase activity" EXACT [] +xref: EC:2.6.1.23 +xref: MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-6784393 "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)" +xref: RHEA:10480 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047579 +name: 4-hydroxymandelate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2)." [EC:1.1.3.19, RHEA:15833] +synonym: "(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.19] +synonym: "L-4-hydroxymandelate oxidase (decarboxylating)" EXACT [EC:1.1.3.19] +xref: EC:1.1.3.19 +xref: KEGG_REACTION:R02673 +xref: MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN +xref: RHEA:15833 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047580 +name: 4-hydroxyproline epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline." [EC:5.1.1.8, RHEA:21152] +synonym: "4-hydroxyproline 2-epimerase activity" EXACT [EC:5.1.1.8] +synonym: "hydroxyproline 2-epimerase activity" EXACT [EC:5.1.1.8] +synonym: "hydroxyproline epimerase activity" EXACT [EC:5.1.1.8] +synonym: "L-hydroxyproline epimerase activity" EXACT [EC:5.1.1.8] +xref: EC:5.1.1.8 +xref: KEGG_REACTION:R03296 +xref: MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN +xref: RHEA:21152 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0047581 +name: 4-methyleneglutamate-ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+)." [EC:6.3.1.7, RHEA:13853] +synonym: "4-methylene-L-glutamate:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.7] +synonym: "4-methyleneglutamine synthetase activity" EXACT [EC:6.3.1.7] +xref: EC:6.3.1.7 +xref: KEGG_REACTION:R02711 +xref: MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN +xref: RHEA:13853 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0047582 +name: 4-methyleneglutaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+)." [EC:3.5.1.67, RHEA:14741] +synonym: "4-methylene-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.67] +synonym: "4-methyleneglutamine amidohydrolase activity" EXACT [EC:3.5.1.67] +synonym: "4-methyleneglutamine deamidase activity" EXACT [EC:3.5.1.67] +xref: EC:3.5.1.67 +xref: KEGG_REACTION:R02712 +xref: MetaCyc:4-METHYLENEGLUTAMINASE-RXN +xref: RHEA:14741 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047583 +name: 4-methyloxaloacetate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate." [EC:3.1.1.44, RHEA:10564] +synonym: "oxaloacetate-4-methyl-ester oxaloacetohydrolase activity" EXACT [EC:3.1.1.44] +xref: EC:3.1.1.44 +xref: KEGG_REACTION:R01144 +xref: MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN +xref: RHEA:10564 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047584 +name: 4-oxalmesaconate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O." [EC:4.2.1.83, RHEA:17401] +synonym: "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]" RELATED [EC:4.2.1.83] +synonym: "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity" EXACT [EC:4.2.1.83] +synonym: "4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity" EXACT [EC:4.2.1.83] +synonym: "4-carboxy-2-oxohexenedioate hydratase activity" EXACT [EC:4.2.1.83] +synonym: "gamma-oxalmesaconate hydratase activity" EXACT [EC:4.2.1.83] +synonym: "oxalmesaconate hydratase activity" EXACT [EC:4.2.1.83] +xref: EC:4.2.1.83 +xref: KEGG_REACTION:R04478 +xref: MetaCyc:RXN-2463 +xref: RHEA:17401 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047585 +name: 4-pyridoxolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+)." [EC:3.1.1.27, RHEA:14301] +synonym: "4-pyridoxolactone lactonohydrolase activity" EXACT [EC:3.1.1.27] +xref: EC:3.1.1.27 +xref: KEGG_REACTION:R02992 +xref: MetaCyc:4-PYRIDOXOLACTONASE-RXN +xref: RHEA:14301 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047586 +name: 5'-acylphosphoadenosine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate." [EC:3.6.1.20, MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN] +synonym: "5'-acylphosphoadenosine acylhydrolase activity" EXACT [EC:3.6.1.20] +synonym: "5-phosphoadenosine hydrolase activity" EXACT [EC:3.6.1.20] +xref: EC:3.6.1.20 +xref: MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN +xref: RHEA:16837 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0047587 +name: 5-alpha-hydroxysteroid dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O." [EC:4.2.1.62, RHEA:22064] +synonym: "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)" EXACT [EC:4.2.1.62] +synonym: "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity" EXACT [EC:4.2.1.62] +synonym: "5alpha-hydroxysteroid dehydratase activity" EXACT [EC:4.2.1.62] +xref: EC:4.2.1.62 +xref: KEGG_REACTION:R03675 +xref: MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN +xref: RHEA:22064 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047588 +name: 5-aminopentanamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3." [EC:3.5.1.30, MetaCyc:5-AMINOPENTANAMIDASE-RXN] +synonym: "5-aminonorvaleramidase activity" EXACT [EC:3.5.1.30] +synonym: "5-aminopentanamide amidohydrolase activity" EXACT [EC:3.5.1.30] +synonym: "5-aminovaleramidase activity" EXACT [EC:3.5.1.30] +xref: EC:3.5.1.30 +xref: MetaCyc:5-AMINOPENTANAMIDASE-RXN +xref: RHEA:15677 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047589 +name: 5-aminovalerate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate." [EC:2.6.1.48, RHEA:10212] +synonym: "5-aminopentanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.48] +synonym: "5-aminovalerate aminotransferase activity" EXACT [] +synonym: "delta-aminovalerate aminotransferase activity" EXACT [EC:2.6.1.48] +synonym: "delta-aminovalerate transaminase activity" EXACT [EC:2.6.1.48] +xref: EC:2.6.1.48 +xref: KEGG_REACTION:R02274 +xref: MetaCyc:VAGL-RXN +xref: RHEA:10212 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047590 +name: 5-dehydro-2-deoxygluconokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate." [EC:2.7.1.92, MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN] +synonym: "5-keto-2-deoxyglucono kinase (phosphorylating)" EXACT [EC:2.7.1.92] +synonym: "5-keto-2-deoxygluconokinase activity" EXACT [EC:2.7.1.92] +synonym: "ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.92] +synonym: "DKH kinase activity" EXACT [EC:2.7.1.92] +xref: EC:2.7.1.92 +xref: MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN +xref: RHEA:13497 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047591 +name: 5-hydroxypentanoate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate." [EC:2.8.3.14, RHEA:23496] +synonym: "5-hydroxyvalerate CoA-transferase activity" EXACT [EC:2.8.3.14] +synonym: "5-hydroxyvalerate coenzyme A transferase activity" EXACT [EC:2.8.3.14] +synonym: "acetyl-CoA:5-hydroxypentanoate CoA-transferase activity" EXACT [EC:2.8.3.14] +xref: EC:2.8.3.14 +xref: KEGG_REACTION:R04057 +xref: MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN +xref: RHEA:23496 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047592 +name: 5-pyridoxate dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)." [EC:1.14.12.5, RHEA:11152] +synonym: "5-pyridoxate oxidase activity" EXACT [EC:1.14.12.5] +synonym: "5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing)" EXACT [EC:1.14.12.5] +xref: EC:1.14.12.5 +xref: KEGG_REACTION:R04570 +xref: MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN +xref: RHEA:11152 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0047593 +name: 6-acetylglucose deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+)." [EC:3.1.1.33, RHEA:18485] +synonym: "6-acetyl-D-glucose acetylhydrolase activity" EXACT [EC:3.1.1.33] +synonym: "6-O-acetylglucose deacetylase activity" EXACT [EC:3.1.1.33] +xref: EC:3.1.1.33 +xref: KEGG_REACTION:R00327 +xref: MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN +xref: RHEA:18485 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047594 +name: 6-beta-hydroxyhyoscyamine epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate." [EC:1.14.20.13, RHEA:12797] +synonym: "(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)" EXACT [EC:1.14.20.13] +synonym: "6beta-hydroxyhyoscyamine epoxidase activity" EXACT [EC:1.14.20.13] +synonym: "hydroxyhyoscyamine dioxygenase activity" EXACT [EC:1.14.20.13] +xref: EC:1.14.20.13 +xref: KEGG_REACTION:R03737 +xref: MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN +xref: RHEA:12797 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0047595 +name: 6-hydroxynicotinate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin." [EC:1.3.7.1, MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN] +synonym: "1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.1] +synonym: "6-hydroxynicotinic reductase activity" EXACT [EC:1.3.7.1] +synonym: "6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.1] +synonym: "6-oxotetrahydro-nicotinate dehydrogenase activity" EXACT [EC:1.3.7.1] +synonym: "6-oxotetrahydronicotinate dehydrogenase activity" EXACT [EC:1.3.7.1] +synonym: "HNA reductase activity" EXACT [EC:1.3.7.1] +xref: EC:1.3.7.1 +xref: MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0047596 +name: 6-methylsalicylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2)." [EC:4.1.1.52, RHEA:23112] +synonym: "6-methylsalicylate carboxy-lyase (3-cresol-forming)" EXACT [EC:4.1.1.52] +synonym: "6-methylsalicylate carboxy-lyase activity" EXACT [EC:4.1.1.52] +synonym: "6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity" EXACT [EC:4.1.1.52] +synonym: "6-MSA decarboxylase activity" EXACT [EC:4.1.1.52] +xref: EC:4.1.1.52 +xref: KEGG_REACTION:R03567 +xref: MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN +xref: RHEA:23112 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047597 +name: 6-oxocineole dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+)." [EC:1.14.13.51, RHEA:24324] +synonym: "6-oxocineole oxygenase activity" EXACT [EC:1.14.13.51] +synonym: "6-oxocineole,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.51] +xref: EC:1.14.13.51 +xref: KEGG_REACTION:R02995 +xref: MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN +xref: RHEA:24324 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047598 +name: 7-dehydrocholesterol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+." [EC:1.3.1.21] +synonym: "7-DHC reductase activity" EXACT [EC:1.3.1.21] +synonym: "cholesterol:NADP+ delta7-oxidoreductase activity" EXACT [EC:1.3.1.21] +synonym: "sterol Delta(7)-reductase activity" BROAD [EC:1.3.1.21] +synonym: "sterol delta7-reductase activity" EXACT [EC:1.3.1.21] +xref: EC:1.3.1.21 +xref: MetaCyc:RXN66-323 +xref: Reactome:R-HSA-196402 "Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol" +xref: Reactome:R-HSA-6807055 "DHCR7 reduces 7-dehydroCHOL to CHOL" +xref: RHEA:23984 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047599 +name: 8-oxocoformycin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH." [EC:1.1.1.235, RHEA:23168] +synonym: "8-ketodeoxycoformycin reductase activity" EXACT [EC:1.1.1.235] +synonym: "coformycin:NADP+ 8-oxidoreductase activity" EXACT [EC:1.1.1.235] +xref: EC:1.1.1.235 +xref: KEGG_REACTION:R03667 +xref: MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN +xref: RHEA:23168 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047600 +name: abequosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid." [EC:2.4.1.60, MetaCyc:ABEQUOSYLTRANSFERASE-RXN] +synonym: "CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity" EXACT [EC:2.4.1.60] +synonym: "trihexose diphospholipid abequosyltransferase activity" EXACT [EC:2.4.1.60] +xref: EC:2.4.1.60 +xref: MetaCyc:ABEQUOSYLTRANSFERASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047601 +name: acetate kinase (diphosphate) activity +namespace: molecular_function +def: "Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate." [EC:2.7.2.12, RHEA:24276] +synonym: "acetate kinase (pyrophosphate) activity" EXACT [EC:2.7.2.12] +synonym: "diphosphate:acetate phosphotransferase activity" EXACT [EC:2.7.2.12] +synonym: "pyrophosphate-acetate phosphotransferase activity" EXACT [EC:2.7.2.12] +xref: EC:2.7.2.12 +xref: KEGG_REACTION:R00320 +xref: MetaCyc:ACETATE-KINASE-PYROPHOSPHATE-RXN +xref: RHEA:24276 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0047602 +name: acetoacetate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2)." [EC:4.1.1.4, RHEA:19729] +synonym: "acetoacetate carboxy-lyase (acetone-forming)" EXACT [EC:4.1.1.4] +synonym: "acetoacetate carboxy-lyase activity" EXACT [EC:4.1.1.4] +synonym: "acetoacetic acid decarboxylase activity" EXACT [EC:4.1.1.4] +xref: EC:4.1.1.4 +xref: KEGG_REACTION:R01366 +xref: MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN +xref: RHEA:19729 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047603 +name: acetoacetyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+)." [EC:3.1.2.11, RHEA:15673] +synonym: "acetoacetyl CoA deacylase activity" EXACT [EC:3.1.2.11] +synonym: "acetoacetyl coenzyme A deacylase activity" EXACT [EC:3.1.2.11] +synonym: "acetoacetyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.11] +xref: EC:3.1.2.11 +xref: KEGG_REACTION:R01358 +xref: MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN +xref: RHEA:15673 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0047604 +name: acetoin racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-acetoin = (R)-acetoin." [EC:5.1.2.4, RHEA:12092] +synonym: "acetylmethylcarbinol racemase activity" EXACT [EC:5.1.2.4] +xref: EC:5.1.2.4 +xref: KEGG_REACTION:R02949 +xref: MetaCyc:ACETOIN-RACEMASE-RXN +xref: RHEA:12092 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0047605 +name: acetolactate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2." [EC:4.1.1.5, MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN] +synonym: "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]" RELATED [EC:4.1.1.5] +synonym: "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity" EXACT [EC:4.1.1.5] +synonym: "alpha-acetolactate decarboxylase activity" EXACT [EC:4.1.1.5] +xref: EC:4.1.1.5 +xref: MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN +xref: RHEA:21580 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047606 +name: hydroxynitrilase activity +namespace: molecular_function +alt_id: GO:0046991 +def: "Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone." [EC:4.1.2, GOC:mah, MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "(S)-acetone-cyanohydrin lyase activity" NARROW [EC:4.1.2.37] +synonym: "2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)" NARROW [EC:4.1.2.37] +synonym: "2-hydroxyisobutyronitrile acetone-lyase activity" NARROW [EC:4.1.2.37] +synonym: "acetone-cyanhydrin lyase activity" NARROW [EC:4.1.2.37] +synonym: "acetone-cyanohydrin acetone-lyase (cyanide-forming)" NARROW [EC:4.1.2.37] +synonym: "acetone-cyanohydrin acetone-lyase activity" NARROW [EC:4.1.2.37] +synonym: "acetone-cyanohydrin lyase activity" NARROW [EC:4..1.2.37] +synonym: "alpha-hydroxynitrile lyase activity" NARROW [EC:4.1.2.37] +synonym: "hydroxynitrile lyase activity" EXACT [] +synonym: "oxynitrilase activity" RELATED [EC:4.1.2.37] +xref: EC:4.1.2.37 +xref: MetaCyc:4.1.2.39-RXN +xref: MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047608 +name: acetylindoxyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown." [EC:1.7.3.2, MetaCyc:ACETYLINDOXYL-OXIDASE-RXN] +synonym: "N-acetylindoxyl:oxygen oxidoreductase activity" EXACT [EC:1.7.3.2] +xref: EC:1.7.3.2 +xref: MetaCyc:ACETYLINDOXYL-OXIDASE-RXN +xref: RHEA:16941 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor + +[Term] +id: GO:0047609 +name: acetylputrescine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine." [EC:3.5.1.62, RHEA:23412] +synonym: "N-acetylputrescine acetylhydrolase activity" EXACT [EC:3.5.1.62] +xref: EC:3.5.1.62 +xref: KEGG_REACTION:R01156 +xref: MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN +xref: RHEA:23412 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0047610 +name: acetylsalicylate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate." [EC:3.1.1.55, RHEA:11752] +synonym: "acetylsalicylate O-acetylhydrolase activity" EXACT [EC:3.1.1.55] +synonym: "acetylsalicylic acid esterase activity" EXACT [EC:3.1.1.55] +synonym: "aspirin esterase activity" EXACT [EC:3.1.1.55] +synonym: "aspirin hydrolase activity" EXACT [EC:3.1.1.55] +xref: EC:3.1.1.55 +xref: KEGG_REACTION:R02942 +xref: MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN +xref: RHEA:11752 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047611 +name: acetylspermidine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine." [EC:3.5.1.48, RHEA:23928] +synonym: "8-N-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] +synonym: "N(1)-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] +synonym: "N(8)-acetylspermidine amidohydrolase activity" RELATED [EC:3.5.1.48] +synonym: "N(8)-acetylspermidine deacetylase activity" RELATED [EC:3.5.1.48] +synonym: "N(8)-monoacetylspermidine deacetylase activity" RELATED [EC:3.5.1.48] +synonym: "N-acetylspermidine deacetylase activity" BROAD [EC:3.5.1.48] +synonym: "N1-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] +synonym: "N8-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] +synonym: "N8-acetylspermidine deacetylase activity" EXACT [EC:3.5.1.48] +synonym: "N8-monoacetylspermidine deacetylase activity" EXACT [EC:3.5.1.48] +xref: EC:3.5.1.48 +xref: KEGG_REACTION:R07300 +xref: MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN +xref: RHEA:23928 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0047612 +name: acid-CoA ligase (GDP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate." [EC:6.2.1.10, RHEA:10968] +synonym: "acid:CoA ligase (GDP-forming)" EXACT [EC:6.2.1.10] +synonym: "acyl coenzyme A synthetase (guanosine diphosphate forming)" EXACT [EC:6.2.1.10] +synonym: "acyl-CoA synthetase (GDP-forming) activity" EXACT [EC:6.2.1.10] +xref: EC:6.2.1.10 +xref: KEGG_REACTION:R00394 +xref: MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN +xref: RHEA:10968 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047613 +name: aconitate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate." [EC:4.1.1.6, RHEA:15253] +synonym: "CAD activity" BROAD [EC:4.1.1.6] +synonym: "cis-aconitate carboxy-lyase (itaconate-forming)" EXACT [EC:4.1.1.6] +synonym: "cis-aconitate carboxy-lyase activity" EXACT [EC:4.1.1.6] +synonym: "cis-aconitic decarboxylase activity" EXACT [EC:4.1.1.6] +xref: EC:4.1.1.6 +xref: KEGG_REACTION:R02243 +xref: MetaCyc:ACONITATE-DECARBOXYLASE-RXN +xref: RHEA:15253 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047614 +name: aconitate delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-aconitate = cis-aconitate." [EC:5.3.3.7, RHEA:17265] +synonym: "aconitate D-isomerase activity" EXACT [] +synonym: "aconitate delta2-delta3-isomerase activity" EXACT [EC:5.3.3.7] +synonym: "aconitate isomerase activity" BROAD [EC:5.3.3.7] +xref: EC:5.3.3.7 +xref: KEGG_REACTION:R02244 +xref: MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN +xref: RHEA:17265 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0047615 +name: actinomycin lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone." [EC:3.1.1.39, MetaCyc:ACTINOMYCIN-LACTONASE-RXN] +synonym: "actinomycin lactonohydrolase activity" EXACT [EC:3.1.1.39] +xref: EC:3.1.1.39 +xref: MetaCyc:ACTINOMYCIN-LACTONASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047616 +name: acyl-CoA dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+." [EC:1.3.1.8, MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN] +synonym: "2-enoyl-CoA reductase activity" EXACT [EC:1.3.1.8] +synonym: "acyl-CoA:NADP+ 2-oxidoreductase activity" EXACT [EC:1.3.1.8] +synonym: "crotonyl coenzyme A reductase activity" EXACT [EC:1.3.1.8] +synonym: "dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.8] +synonym: "enoyl coenzyme A reductase activity" EXACT [EC:1.3.1.8] +xref: EC:1.3.1.8 +xref: MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047617 +name: acyl-CoA hydrolase activity +namespace: molecular_function +alt_id: GO:0008778 +alt_id: GO:0016291 +alt_id: GO:0016292 +def: "Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate." [EC:3.1.2.20, MetaCyc:ACYL-COA-HYDROLASE-RXN] +synonym: "acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.20] +synonym: "acyl coenzyme A thioesterase activity" EXACT [EC:3.1.2.20] +synonym: "acyl-CoA thioesterase activity" EXACT [] +synonym: "acyl-CoA thioesterase I activity" NARROW [] +synonym: "acyl-CoA thioesterase II activity" NARROW [] +synonym: "acyl-CoA thiolesterase activity" EXACT [] +synonym: "thioesterase B" RELATED [EC:3.1.2.20] +synonym: "thioesterase II" RELATED [EC:3.1.2.20] +xref: EC:3.1.2 +xref: EC:3.1.2.20 +xref: MetaCyc:ACYL-COA-HYDROLASE-RXN +xref: Reactome:R-HSA-5690042 "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA" +xref: Reactome:R-HSA-5690043 "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA" +xref: Reactome:R-HSA-5690066 "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA" +xref: Reactome:R-HSA-6810474 "NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT" +xref: RHEA:16781 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0047618 +name: acylagmatine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate." [EC:3.5.1.40, RHEA:15065] +synonym: "acylagmatine amidohydrolase activity" EXACT [EC:3.5.1.40] +synonym: "acylagmatine deacylase activity" EXACT [EC:3.5.1.40] +synonym: "benzoylagmatine amidohydrolase activity" EXACT [EC:3.5.1.40] +xref: EC:3.5.1.40 +xref: KEGG_REACTION:R01425 +xref: MetaCyc:ACYLAGMATINE-AMIDASE-RXN +xref: RHEA:15065 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047619 +name: acylcarnitine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine." [EC:3.1.1.28, MetaCyc:ACYLCARNITINE-HYDROLASE-RXN] +synonym: "carnitine ester hydrolase activity" EXACT [EC:3.1.1.28] +synonym: "HACH" RELATED [EC:3.1.1.28] +synonym: "high activity acylcarnitine hydrolase activity" EXACT [EC:3.1.1.28] +synonym: "long-chain acyl-L-carnitine hydrolase activity" EXACT [EC:3.1.1.28] +synonym: "O-acylcarnitine acylhydrolase activity" EXACT [EC:3.1.1.28] +synonym: "palmitoyl carnitine hydrolase activity" EXACT [EC:3.1.1.28] +synonym: "palmitoyl-L-carnitine hydrolase activity" EXACT [EC:3.1.1.28] +synonym: "palmitoylcarnitine hydrolase activity" EXACT [EC:3.1.1.28] +xref: EC:3.1.1.28 +xref: MetaCyc:ACYLCARNITINE-HYDROLASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047620 +name: acylglycerol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate." [EC:2.7.1.94, MetaCyc:ACYLGLYCEROL-KINASE-RXN] +synonym: "ATP:acylglycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.94] +synonym: "MGK" RELATED [EC:2.7.1.94] +synonym: "monoacylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.94] +synonym: "monoacylglycerol kinase activity" EXACT [EC:2.7.1.94] +synonym: "monoglyceride kinase activity" EXACT [EC:2.7.1.94] +synonym: "monoglyceride phosphokinase activity" EXACT [EC:2.7.1.94] +synonym: "sn-2-monoacylglycerol kinase activity" EXACT [EC:2.7.1.94] +xref: EC:2.7.1.94 +xref: MetaCyc:ACYLGLYCEROL-KINASE-RXN +xref: Reactome:R-HSA-5696074 "AGK:Mg2+ phosphorylates MAG, DAG" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047621 +name: acylpyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate." [EC:3.7.1.5, MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN] +synonym: "3-acylpyruvate acylhydrolase activity" EXACT [EC:3.7.1.5] +xref: EC:3.7.1.5 +xref: MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN +xref: UM-BBD_reactionID:r1401 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0047622 +name: adenosine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine + H2O = D-ribose + adenine." [EC:3.2.2.7, MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN] +synonym: "adenosinase activity" EXACT [EC:3.2.2.7] +synonym: "adenosine hydrolase activity" EXACT [EC:3.2.2.7] +synonym: "adenosine ribohydrolase activity" EXACT [EC:3.2.2.7] +synonym: "ANase activity" EXACT [EC:3.2.2.7] +synonym: "N-ribosyladenine ribohydrolase activity" EXACT [EC:3.2.2.7] +xref: EC:3.2.2.7 +xref: MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN +xref: RHEA:18669 +is_a: GO:0008477 ! purine nucleosidase activity + +[Term] +id: GO:0047623 +name: adenosine-phosphate deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP." [EC:3.5.4.17, GOC:bf, MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN] +comment: Consider instead annotating to one of the more specific terms: AMP deaminase activity ; GO:0003876, ADP deaminase activity ; GO:0047629, or ATP deaminase activity ; GO:0047692. +synonym: "adenine nucleotide deaminase activity" EXACT [EC:3.5.4.17] +synonym: "adenosine (phosphate) deaminase activity" EXACT [EC:3.5.4.17] +synonym: "adenosine-phosphate aminohydrolase activity" EXACT [EC:3.5.4.17] +xref: EC:3.5.4.17 +xref: MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047624 +name: adenosine-tetraphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate." [EC:3.6.1.14, MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN] +synonym: "adenosine-tetraphosphate phosphohydrolase activity" EXACT [EC:3.6.1.14] +xref: EC:3.6.1.14 +xref: MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN +xref: RHEA:24500 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047625 +name: adenosylmethionine cyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone." [EC:2.5.1.4, RHEA:21932] +synonym: "adenosyl methionine cyclotransferase activity" EXACT [] +synonym: "adenosylmethioninase activity" EXACT [EC:2.5.1.4] +synonym: "S-adenosyl-L-methionine alkyltransferase (cyclizing)" EXACT [EC:2.5.1.4] +xref: EC:2.5.1.4 +xref: KEGG_REACTION:R00180 +xref: MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN +xref: RHEA:21932 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047626 +name: adenosylmethionine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+)." [EC:3.3.1.2, RHEA:14645] +synonym: "adenosyl methionine hydrolase activity" EXACT [] +synonym: "adenosylmethionine lyase activity" EXACT [EC:3.3.1.2] +synonym: "methylmethionine-sulfonium-salt hydrolase activity" EXACT [EC:3.3.1.2] +synonym: "S-adenosyl-L-methionine hydrolase activity" EXACT [EC:3.3.1.2] +synonym: "S-adenosylmethionine cleaving enzyme activity" EXACT [EC:3.3.1.2] +xref: EC:3.3.1.2 +xref: KEGG_REACTION:R00175 +xref: MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN +xref: RHEA:14645 +is_a: GO:0016802 ! trialkylsulfonium hydrolase activity + +[Term] +id: GO:0047627 +name: adenylylsulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate." [EC:3.6.2.1, RHEA:17041] +synonym: "adenosine 5-phosphosulfate sulfohydrolase activity" EXACT [EC:3.6.2.1] +synonym: "adenylylsulfate sulfohydrolase activity" EXACT [EC:3.6.2.1] +synonym: "adenylylsulphatase activity" EXACT [] +xref: EC:3.6.2.1 +xref: KEGG_REACTION:R00531 +xref: MetaCyc:ADENYLYLSULFATASE-RXN +xref: RHEA:17041 +is_a: GO:0016819 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides + +[Term] +id: GO:0047628 +name: ADP-thymidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate." [EC:2.7.1.118, MetaCyc:ADP--THYMIDINE-KINASE-RXN] +synonym: "adenosine diphosphate-thymidine phosphotransferase activity" EXACT [EC:2.7.1.118] +synonym: "ADP:dThd phosphotransferase activity" EXACT [EC:2.7.1.118] +synonym: "ADP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.118] +xref: EC:2.7.1.118 +xref: MetaCyc:ADP--THYMIDINE-KINASE-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047629 +name: ADP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP + H2O = IDP + NH3." [EC:3.5.4.7, MetaCyc:ADP-DEAMINASE-RXN] +synonym: "adenosine diphosphate deaminase activity" EXACT [EC:3.5.4.7] +synonym: "adenosinepyrophosphate deaminase activity" EXACT [EC:3.5.4.7] +synonym: "ADP aminohydrolase activity" EXACT [EC:3.5.4.7] +xref: EC:3.5.4.7 +xref: MetaCyc:ADP-DEAMINASE-RXN +xref: RHEA:12741 +is_a: GO:0047623 ! adenosine-phosphate deaminase activity + +[Term] +id: GO:0047630 +name: ADP-phosphoglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate." [EC:3.1.3.28, RHEA:15861] +synonym: "3-(ADP)-2-phosphoglycerate phosphohydrolase activity" EXACT [EC:3.1.3.28] +synonym: "adenosine diphosphate phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.28] +synonym: "ADPphosphoglycerate phosphatase activity" EXACT [EC:3.1.3.28] +xref: EC:3.1.3.28 +xref: KEGG_REACTION:R03969 +xref: MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN +xref: RHEA:15861 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047631 +name: ADP-ribose diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate." [EC:3.6.1.13, MetaCyc:ADP-RIBOSE-PYROPHOSPHATASE-RXN] +synonym: "adenosine diphosphoribose pyrophosphatase activity" EXACT [] +synonym: "ADP-ribose phosphohydrolase activity" EXACT [] +synonym: "ADP-ribose pyrophosphatase activity" EXACT [] +synonym: "ADP-ribose ribophosphohydrolase activity" EXACT [EC:3.6.1.13] +synonym: "ADPR-PPase activity" EXACT [] +synonym: "ADPribose diphosphatase activity" EXACT [EC:3.6.1.13] +synonym: "ADPribose pyrophosphatase activity" EXACT [EC:3.6.1.13] +xref: EC:3.6.1.13 +xref: MetaCyc:RXN0-1441 +xref: Reactome:R-HSA-2393939 "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP" +xref: Reactome:R-HSA-2393954 "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP" +xref: Reactome:R-HSA-5696049 "ADPRM hydrolyses ADP-ribose to R5P and AMP" +xref: RHEA:10412 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047632 +name: agmatine deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3." [EC:3.5.3.12, MetaCyc:AGMATINE-DEIMINASE-RXN] +synonym: "agmatine amidinohydrolase" BROAD [EC:3.5.3.12] +synonym: "agmatine iminohydrolase activity" EXACT [EC:3.5.3.12] +xref: EC:3.5.3.12 +xref: MetaCyc:AGMATINE-DEIMINASE-RXN +xref: RHEA:18037 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047633 +name: agmatine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+)." [EC:2.7.3.10, RHEA:15953] +synonym: "ATP:agmatine 4-N-phosphotransferase activity" EXACT [EC:2.7.3.10] +synonym: "ATP:agmatine N4-phosphotransferase activity" EXACT [EC:2.7.3.10] +synonym: "phosphagen phosphokinase activity" RELATED [EC:2.7.3.10] +xref: EC:2.7.3.10 +xref: KEGG_REACTION:R01417 +xref: MetaCyc:AGMATINE-KINASE-RXN +xref: RHEA:15953 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0047634 +name: agmatine N4-coumaroyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+)." [EC:2.3.1.64, RHEA:13405] +synonym: "4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity" EXACT [EC:2.3.1.64] +synonym: "4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity" EXACT [EC:2.3.1.64] +synonym: "agmatine coumaroyltransferase activity" EXACT [EC:2.3.1.64] +synonym: "p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity" EXACT [EC:2.3.1.64] +xref: EC:2.3.1.64 +xref: KEGG_REACTION:R01617 +xref: MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN +xref: RHEA:13405 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047635 +name: alanine-oxo-acid transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid." [EC:2.6.1.12, MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN] +synonym: "alanine--oxo-acid aminotransferase activity" EXACT [EC:2.6.1.12] +synonym: "alanine-keto acid aminotransferase activity" EXACT [EC:2.6.1.12] +synonym: "alanine-oxo acid aminotransferase activity" EXACT [EC:2.6.1.12] +synonym: "alanine-oxo-acid aminotransferase activity" EXACT [] +synonym: "L-alanine-alpha-keto acid aminotransferase activity" EXACT [EC:2.6.1.12] +synonym: "L-alanine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.12] +synonym: "leucine-alanine transaminase activity" EXACT [EC:2.6.1.12] +xref: EC:2.6.1.12 +xref: MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047636 +name: alanopine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate." [EC:1.5.1.17, RHEA:17589] +synonym: "2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)" EXACT [EC:1.5.1.17] +synonym: "ADH" RELATED [EC:1.5.1.17] +synonym: "alanopine: NAD oxidoreductase activity" EXACT [EC:1.5.1.17] +synonym: "alanopine:NAD oxidoreductase activity" EXACT [EC:1.5.1.17] +synonym: "alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity" EXACT [EC:1.5.1.17] +synonym: "ALPDH" RELATED [EC:1.5.1.17] +synonym: "meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.17] +xref: EC:1.5.1.17 +xref: KEGG_REACTION:R00398 +xref: MetaCyc:ALANOPINE-DEHYDROGENASE-RXN +xref: RHEA:17589 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047637 +name: alanylphosphatidylglycerol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol." [EC:2.3.2.11, MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN] +synonym: "alanyl phosphatidylglycerol synthetase activity" EXACT [EC:2.3.2.11] +synonym: "L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity" EXACT [EC:2.3.2.11] +synonym: "O-alanylphosphatidylglycerol synthase activity" EXACT [EC:2.3.2.11] +xref: EC:2.3.2.11 +xref: MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0047638 +name: albendazole monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+)." [EC:1.14.13.32, RHEA:10796] +synonym: "albendazole oxidase activity" EXACT [EC:1.14.13.32] +synonym: "albendazole sulfoxidase activity" EXACT [EC:1.14.13.32] +synonym: "albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)" EXACT [EC:1.14.13.32] +xref: EC:1.14.13.32 +xref: KEGG_REACTION:R03712 +xref: MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN +xref: RHEA:10796 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047639 +name: alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2." [EC:1.1.3.13, MetaCyc:ALCOHOL-OXIDASE-RXN] +comment: Note that the enzyme alcohol oxidase also has methanol oxidase activity (GO:0046563). +synonym: "alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.13] +synonym: "AOX activity" EXACT [EC:1.1.3.13] +synonym: "ethanol oxidase activity" EXACT [EC:1.1.3.13] +xref: EC:1.1.3.13 +xref: MetaCyc:ALCOHOL-OXIDASE-RXN +xref: RHEA:19829 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047640 +name: aldose 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH." [EC:1.1.1.121, MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN] +synonym: "aldose dehydrogenase activity" EXACT [EC:1.1.1.121] +synonym: "D-aldose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.121] +synonym: "dehydrogenase, D-aldohexose" EXACT [EC:1.1.1.121] +xref: EC:1.1.1.121 +xref: MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047641 +name: aldose-6-phosphate reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH." [EC:1.1.1.200, RHEA:20037] +synonym: "A6PR" RELATED [EC:1.1.1.200] +synonym: "alditol 6-phosphate:NADP 1-oxidoreductase activity" EXACT [EC:1.1.1.200] +synonym: "aldose 6-phosphate reductase activity" EXACT [EC:1.1.1.200] +synonym: "aldose-6-P reductase activity" EXACT [EC:1.1.1.200] +synonym: "aldose-6-phosphate reductase activity" EXACT [EC:1.1.1.200] +synonym: "D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.200] +synonym: "NADP-dependent aldose 6-phosphate reductase activity" EXACT [EC:1.1.1.200] +synonym: "NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.200] +xref: EC:1.1.1.200 +xref: KEGG_REACTION:R00834 +xref: MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN +xref: RHEA:20037 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047642 +name: aldose beta-D-fructosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside." [EC:2.4.1.162, MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN] +synonym: "aldose b-D-fructosyltransferase activity" EXACT [] +synonym: "alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.162] +xref: EC:2.4.1.162 +xref: MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN +is_a: GO:0050738 ! fructosyltransferase activity + +[Term] +id: GO:0047643 +name: alginate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1)." [EC:2.4.1.33, MetaCyc:ALGINATE-SYNTHASE-RXN] +synonym: "GDP-D-mannuronate:alginate D-mannuronyltransferase activity" EXACT [EC:2.4.1.33] +synonym: "mannuronosyl transferase activity" EXACT [EC:2.4.1.33] +xref: EC:2.4.1.33 +xref: MetaCyc:ALGINATE-SYNTHASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047644 +name: alizarin 2-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP." [EC:2.4.1.103, RHEA:20677] +synonym: "alizarin 2-b-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.103] +synonym: "UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity" EXACT [EC:2.4.1.103] +synonym: "uridine diphosphoglucose-alizarin glucosyltransferase activity" EXACT [EC:2.4.1.103] +xref: EC:2.4.1.103 +xref: KEGG_REACTION:R03573 +xref: MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:20677 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047645 +name: alkan-1-ol dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor." [EC:1.1.99.20, MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN] +synonym: "alkan-1-ol:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.20] +synonym: "alkan-1-ol:acceptor oxidoreductase activity" EXACT [EC:1.1.99.20] +synonym: "polyethylene glycol dehydrogenase activity" NARROW [EC:1.1.99.20] +xref: EC:1.1.99.20 +xref: MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN +xref: RHEA:14685 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047646 +name: alkanal monooxygenase (FMN-linked) activity +namespace: molecular_function +def: "Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light." [EC:1.14.14.3, MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN] +synonym: "aldehyde monooxygenase activity" BROAD [EC:1.14.14.3] +synonym: "alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)" EXACT [EC:1.14.14.3] +synonym: "bacterial luciferase activity" EXACT [EC:1.14.14.3] +synonym: "vibrio fischeri luciferase activity" EXACT [EC:1.14.14.3] +xref: EC:1.14.14.3 +xref: MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047647 +name: alkylacetylglycerophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate." [EC:3.1.3.59, RHEA:18221] +synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.59] +synonym: "1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity" EXACT [EC:3.1.3.59] +synonym: "alkylacetylglycerophosphate phosphatase activity" EXACT [EC:3.1.3.59] +xref: EC:3.1.3.59 +xref: KEGG_REACTION:R03454 +xref: MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN +xref: RHEA:18221 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047648 +name: alkylamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium." [EC:3.5.1.39, RHEA:20081] +synonym: "N-methylhexanamide amidohydrolase activity" EXACT [EC:3.5.1.39] +xref: EC:3.5.1.39 +xref: KEGG_REACTION:R03620 +xref: MetaCyc:ALKYLAMIDASE-RXN +xref: RHEA:20081 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047649 +name: alkylglycerol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+)." [EC:2.7.1.93, RHEA:16937] +synonym: "1-alkylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.93] +synonym: "alkylglycerol phosphotransferase activity" EXACT [EC:2.7.1.93] +synonym: "ATP-alkylglycerol phosphotransferase activity" EXACT [EC:2.7.1.93] +synonym: "ATP:1-alkyl-sn-glycerol phosphotransferase activity" EXACT [EC:2.7.1.93] +synonym: "ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.93] +xref: EC:2.7.1.93 +xref: KEGG_REACTION:R04126 +xref: MetaCyc:ALKYLGLYCEROL-KINASE-RXN +xref: RHEA:16937 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047650 +name: alkylglycerone kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+)." [EC:2.7.1.84, RHEA:23088] +synonym: "alkyldihydroxyacetone kinase (phosphorylating)" EXACT [EC:2.7.1.84] +synonym: "alkyldihydroxyacetone kinase activity" EXACT [EC:2.7.1.84] +synonym: "ATP:O-alkylglycerone phosphotransferase activity" EXACT [EC:2.7.1.84] +xref: EC:2.7.1.84 +xref: KEGG_REACTION:R03944 +xref: MetaCyc:ALKYLGLYCERONE-KINASE-RXN +xref: RHEA:23088 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047651 +name: alkylhalidase activity +namespace: molecular_function +def: "Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+)." [EC:3.8.1.1, RHEA:13765] +synonym: "alkyl-halide halidohydrolase activity" EXACT [EC:3.8.1.1] +synonym: "haloalkane halidohydrolase activity" EXACT [EC:3.8.1.1] +synonym: "halogenase activity" RELATED [EC:3.8.1.1] +xref: EC:3.8.1.1 +xref: KEGG_REACTION:R03523 +xref: MetaCyc:ALKYLHALIDASE-RXN +xref: RHEA:13765 +is_a: GO:0019120 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds + +[Term] +id: GO:0047652 +name: allantoate deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine." [EC:3.5.3.9, MetaCyc:ALLANTOATE-DEIMINASE-RXN] +synonym: "allantoate amidinohydrolase (decarboxylating)" EXACT [EC:3.5.3.9] +synonym: "allantoate amidohydrolase activity" EXACT [EC:3.5.3.9] +xref: EC:3.5.3.9 +xref: MetaCyc:ALLANTOATE-DEIMINASE-RXN +xref: RHEA:27485 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047653 +name: allantoin racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin." [EC:5.1.99.3, RHEA:10804] +xref: EC:5.1.99.3 +xref: KEGG_REACTION:R03925 +xref: MetaCyc:ALLANTOIN-RACEMASE-RXN +xref: RHEA:10804 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0047654 +name: alliin lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate." [EC:4.4.1.4, MetaCyc:ALLIIN-LYASE-RXN] +synonym: "alkylcysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] +synonym: "alliin alkyl-sulfenate-lyase activity" EXACT [EC:4.4.1.4] +synonym: "alliinase activity" EXACT [EC:4.4.1.4] +synonym: "cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] +synonym: "cysteine sulphoxide lyase activity" EXACT [EC:4.4.1.4] +synonym: "L-cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] +synonym: "S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)" EXACT [EC:4.4.1.4] +synonym: "S-alkylcysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] +xref: EC:4.4.1.4 +xref: MetaCyc:ALLIIN-LYASE-RXN +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0047655 +name: allyl-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH." [EC:1.1.1.54, RHEA:12168] +synonym: "allyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.54] +xref: EC:1.1.1.54 +xref: KEGG_REACTION:R03572 +xref: MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN +xref: RHEA:12168 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047656 +name: alpha,alpha-trehalose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate." [EC:2.4.1.64, MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN] +synonym: "a,a-trehalose phosphorylase activity" EXACT [] +synonym: "alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.64] +synonym: "trehalose phosphorylase" BROAD [EC:2.4.1.64] +xref: EC:2.4.1.64 +xref: MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN +xref: RHEA:23512 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0047657 +name: alpha-1,3-glucan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1." [EC:2.4.1.183, MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN] +synonym: "1,3-alpha-D-glucan synthase activity" EXACT [EC:2.4.1.183] +synonym: "1,3-alpha-glucan synthase activity" EXACT [] +synonym: "a-1,3-glucan synthase activity" EXACT [] +synonym: "UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] +synonym: "UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] +synonym: "uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.183] +xref: EC:2.4.1.183 +xref: MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047658 +name: alpha-amino-acid esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol." [EC:3.1.1.43, MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN] +synonym: "a-amino-acid esterase activity" EXACT [] +synonym: "alpha-amino acid ester hydrolase activity" EXACT [EC:3.1.1.43] +synonym: "alpha-amino-acid ester hydrolase activity" EXACT [EC:3.1.1.43] +synonym: "alpha-amino-acid-ester aminoacylhydrolase activity" EXACT [EC:3.1.1.43] +xref: EC:3.1.1.43 +xref: MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN +xref: Reactome:R-HSA-6784959 "BPHL hydrolyses VACV to ACV" +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047659 +name: alpha-santonin 1,2-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+." [EC:1.3.1.47, MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN] +synonym: "1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity" EXACT [EC:1.3.1.47] +synonym: "a-santonin 1,2-reductase activity" EXACT [] +xref: EC:1.3.1.47 +xref: MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047660 +name: amidinoaspartase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea." [EC:3.5.3.14, RHEA:14849] +synonym: "amidinoaspartic amidinohydrolase activity" EXACT [EC:3.5.3.14] +synonym: "N-amidino-L-aspartate amidinohydrolase activity" EXACT [EC:3.5.3.14] +xref: EC:3.5.3.14 +xref: KEGG_REACTION:R00777 +xref: MetaCyc:AMIDINOASPARTASE-RXN +xref: RHEA:14849 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047661 +name: amino-acid racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: an L-amino acid = a D-amino acid." [EC:5.1.1.10, MetaCyc:AMINO-ACID-RACEMASE-RXN] +synonym: "L-amino acid racemase activity" EXACT [EC:5.1.1.10] +xref: EC:5.1.1.10 +xref: MetaCyc:AMINO-ACID-RACEMASE-RXN +xref: RHEA:18317 +is_a: GO:0036361 ! racemase activity, acting on amino acids and derivatives + +[Term] +id: GO:0047662 +name: aminobenzoate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2." [EC:4.1.1.24, MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN] +synonym: "aminobenzoate carboxy-lyase (aniline-forming)" EXACT [EC:4.1.1.24] +synonym: "aminobenzoate carboxy-lyase activity" EXACT [EC:4.1.1.24] +xref: EC:4.1.1.24 +xref: MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047663 +name: aminoglycoside 6'-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring." [EC:2.3.1.82, RHEA:16449] +synonym: "6'-aminoglycoside-N-acetyltransferase activity" EXACT [EC:2.3.1.82] +synonym: "AAC(6') activity" RELATED [EC:2.3.1.82] +synonym: "acetyl-CoA:kanamycin-B N6'-acetyltransferase activity" NARROW [EC:2.3.1.82] +synonym: "aminoglycoside N6'-acetyltransferase activity" EXACT [] +synonym: "aminoglycoside-6'-acetyltransferase activity" EXACT [EC:2.3.1.82] +synonym: "aminoglycoside-6-N-acetyltransferase activity" EXACT [EC:2.3.1.82] +synonym: "kanamycin 6'-N-acetyltransferase activity" NARROW [] +xref: EC:2.3.1.82 +xref: KEGG_REACTION:R01889 +xref: MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN +xref: RHEA:16449 +is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity + +[Term] +id: GO:0047664 +name: aminoimidazolase activity +namespace: molecular_function +def: "Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH(3)." [EC:3.5.4.8, MetaCyc:AMINOIMIDAZOLASE-RXN, RHEA:22348] +synonym: "4-aminoimidazole aminohydrolase activity" EXACT [EC:3.5.4.8] +synonym: "4-aminoimidazole hydrolase activity" EXACT [EC:3.5.4.8] +xref: EC:3.5.4.8 +xref: MetaCyc:R13-RXN +xref: RHEA:22348 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0047665 +name: aminolevulinate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine." [EC:2.6.1.43, RHEA:12480] +synonym: "4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "4,5-dioxovaleric acid aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "4,5-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] +synonym: "4,5-dioxovaleric transaminase activity" EXACT [EC:2.6.1.43] +synonym: "5-aminolevulinate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "5-aminolevulinic acid transaminase activity" EXACT [EC:2.6.1.43] +synonym: "alanine-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "alanine-gamma,delta-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "alanine:4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "aminolevulinate aminotransferase activity" EXACT [] +synonym: "aminolevulinic acid transaminase activity" EXACT [EC:2.6.1.43] +synonym: "dioxovalerate transaminase activity" EXACT [EC:2.6.1.43] +synonym: "DOVA transaminase activity" EXACT [EC:2.6.1.43] +synonym: "gamma,delta-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "gamma,delta-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] +synonym: "L-alanine-4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] +synonym: "L-alanine:4,5-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] +synonym: "L-alanine:dioxovalerate transaminase activity" EXACT [EC:2.6.1.43] +xref: EC:2.6.1.43 +xref: KEGG_REACTION:R02271 +xref: MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN +xref: RHEA:12480 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047666 +name: ammonia kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate." [EC:2.7.3.8, RHEA:11024] +synonym: "ATP:ammonia phosphotransferase activity" EXACT [EC:2.7.3.8] +synonym: "phosphoramidate-adenosine diphosphate phosphotransferase activity" EXACT [EC:2.7.3.8] +synonym: "phosphoramidate-ADP-phosphotransferase activity" EXACT [EC:2.7.3.8] +xref: EC:2.7.3.8 +xref: KEGG_REACTION:R00141 +xref: MetaCyc:AMMONIA-KINASE-RXN +xref: RHEA:11024 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0047667 +name: AMP-thymidine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate." [EC:2.7.1.114, MetaCyc:AMP--THYMIDINE-KINASE-RXN] +synonym: "adenylate-nucleoside phosphotransferase activity" EXACT [EC:2.7.1.114] +synonym: "adenylic acid:deoxythymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] +synonym: "AMP:deoxythymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] +synonym: "AMP:deoxythymidine kinase activity" EXACT [EC:2.7.1.114] +synonym: "AMP:dThd kinase activity" EXACT [EC:2.7.1.114] +synonym: "AMP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] +synonym: "thymidine phosphotransferase activity" EXACT [EC:2.7.1.114] +xref: EC:2.7.1.114 +xref: MetaCyc:AMP--THYMIDINE-KINASE-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047668 +name: amygdalin beta-glucosidase activity +namespace: molecular_function +alt_id: GO:0080080 +def: "Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose." [EC:3.2.1.117, RHEA:14177] +synonym: "(R)-amygdalin beta-glucosidase activity" EXACT [] +synonym: "amygdalin b-glucosidase activity" EXACT [] +synonym: "amygdalin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.117] +synonym: "amygdalin glucosidase activity" EXACT [EC:3.2.1.117] +synonym: "amygdalin hydrolase activity" EXACT [EC:3.2.1.117] +synonym: "amygdalinase" BROAD [EC:3.2.1.117] +xref: EC:3.2.1.117 +xref: KEGG_REACTION:R02985 +xref: MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN +xref: RHEA:14177 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0047669 +name: amylosucrase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1)." [EC:2.4.1.4, MetaCyc:AMYLOSUCRASE-RXN] +synonym: "sucrose-1,4-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.4] +synonym: "sucrose-glucan glucosyltransferase activity" EXACT [EC:2.4.1.4] +synonym: "sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.4] +xref: EC:2.4.1.4 +xref: MetaCyc:AMYLOSUCRASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047670 +name: anhydrotetracycline monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+)." [EC:1.14.13.38, RHEA:11976] +synonym: "anhydrotetracycline oxygenase activity" EXACT [EC:1.14.13.38] +synonym: "anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.38] +synonym: "ATC oxygenase activity" EXACT [EC:1.14.13.38] +xref: EC:1.14.13.38 +xref: KEGG_REACTION:R04060 +xref: MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN +xref: RHEA:11976 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047671 +name: anthranilate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+)." [EC:2.7.7.55, RHEA:22412] +synonym: "anthranilic acid adenylyltransferase activity" EXACT [EC:2.7.7.55] +synonym: "ATP:anthranilate adenylyltransferase activity" EXACT [] +synonym: "ATP:anthranilate N-adenylyltransferase activity" EXACT [EC:2.7.7.55] +xref: EC:2.7.7.55 +xref: KEGG_REACTION:R00979 +xref: MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN +xref: RHEA:22412 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0047672 +name: anthranilate N-benzoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA." [EC:2.3.1.144, RHEA:21600] +synonym: "benzoyl-CoA:anthranilate N-benzoyltransferase" BROAD [EC:2.3.1.144] +xref: EC:2.3.1.144 +xref: KEGG_REACTION:R02453 +xref: MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN +xref: RHEA:21600 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047673 +name: anthranilate N-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA." [EC:2.3.1.113, RHEA:17557] +synonym: "malonyl-CoA:anthranilate N-malonyltransferase activity" EXACT [EC:2.3.1.113] +xref: EC:2.3.1.113 +xref: KEGG_REACTION:R00989 +xref: MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN +xref: RHEA:17557 +is_a: GO:0050735 ! N-malonyltransferase activity + +[Term] +id: GO:0047674 +name: apiose 1-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH." [EC:1.1.1.114, RHEA:15301] +synonym: "D-apiitol reductase activity" EXACT [EC:1.1.1.114] +synonym: "D-apiitol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.114] +synonym: "D-apiose reductase activity" EXACT [EC:1.1.1.114] +xref: EC:1.1.1.114 +xref: KEGG_REACTION:R03577 +xref: MetaCyc:APIOSE-1-REDUCTASE-RXN +xref: RHEA:15301 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047675 +name: arabinonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O." [EC:4.2.1.5, RHEA:21836] +synonym: "D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)" EXACT [EC:4.2.1.5] +synonym: "D-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.5] +xref: EC:4.2.1.5 +xref: KEGG_REACTION:R03032 +xref: MetaCyc:ARABINONATE-DEHYDRATASE-RXN +xref: RHEA:21836 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047676 +name: arachidonate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+)." [EC:6.2.1.15, RHEA:19713] +synonym: "arachidonate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.15] +synonym: "arachidonoyl-CoA synthetase activity" EXACT [EC:6.2.1.15] +xref: EC:6.2.1.15 +xref: KEGG_REACTION:R01598 +xref: MetaCyc:ARACHIDONATE--COA-LIGASE-RXN +xref: RHEA:19713 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047677 +name: arachidonate 8(R)-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate." [EC:1.13.11.40, RHEA:14985] +comment: This activity produces the R-enantiomer of HPETE, 8(R)-HPETE. For the reaction producing the S-enantiomer, see GO:0036403. +synonym: "8(R)-lipoxygenase activity" EXACT [EC:1.13.11.40] +synonym: "8-lipoxygenase activity" NARROW [EC:1.13.11.40] +synonym: "arachidonate 8-lipoxygenase activity" BROAD [GOC:lb] +synonym: "arachidonate:oxygen 8-oxidoreductase activity" EXACT [EC:1.13.11.40] +xref: EC:1.13.11.40 +xref: KEGG_REACTION:R01594 +xref: MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN +xref: RHEA:14985 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047678 +name: arginine 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O." [EC:1.13.12.1, RHEA:10548] +synonym: "arginine decarboxy-oxidase activity" EXACT [EC:1.13.12.1] +synonym: "arginine monooxygenase activity" EXACT [EC:1.13.12.1] +synonym: "arginine oxygenase (decarboxylating) activity" EXACT [EC:1.13.12.1] +synonym: "L-arginine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.1] +xref: EC:1.13.12.1 +xref: KEGG_REACTION:R00559 +xref: MetaCyc:ARGININE-2-MONOOXYGENASE-RXN +xref: RHEA:10548 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0047679 +name: arginine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine = D-arginine." [EC:5.1.1.9, MetaCyc:ARGININE-RACEMASE-RXN] +xref: EC:5.1.1.9 +xref: MetaCyc:ARGININE-RACEMASE-RXN +xref: RHEA:18069 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0047680 +name: aryl-acylamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+)." [EC:3.5.1.13, RHEA:20297] +synonym: "AAA-1" RELATED [EC:3.5.1.13] +synonym: "AAA-2" RELATED [EC:3.5.1.13] +synonym: "aryl-acylamide amidohydrolase activity" EXACT [EC:3.5.1.13] +synonym: "brain acetylcholinesterase (is associated with AAA-2)" EXACT [EC:3.5.1.13] +synonym: "pseudocholinesterase (associated with arylacylamidase)" EXACT [EC:3.5.1.13] +xref: EC:3.5.1.13 +xref: KEGG_REACTION:R01862 +xref: MetaCyc:ARYL-ACYLAMIDASE-RXN +xref: RHEA:20297 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047681 +name: aryl-alcohol dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH." [EC:1.1.1.91, MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN] +synonym: "aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.91] +synonym: "aryl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.91] +synonym: "NADPH-linked benzaldehyde reductase activity" EXACT [EC:1.1.1.91] +xref: EC:1.1.1.91 +xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047682 +name: aryl-alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2." [EC:1.1.3.7, MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN] +synonym: "arom. alcohol oxidase activity" EXACT [EC:1.1.3.7] +synonym: "aryl alcohol oxidase activity" EXACT [EC:1.1.3.7] +synonym: "aryl-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.7] +synonym: "veratryl alcohol oxidase activity" NARROW [EC:1.1.3.7] +xref: EC:1.1.3.7 +xref: MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047683 +name: aryl-aldehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP." [EC:1.2.1.30, MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN] +synonym: "aromatic acid reductase activity" EXACT [EC:1.2.1.30] +synonym: "aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)" EXACT [EC:1.2.1.30] +xref: EC:1.2.1.30 +xref: MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN +is_a: GO:0033721 ! aldehyde dehydrogenase (NADP+) activity + +[Term] +id: GO:0047684 +name: arylamine glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine." [EC:2.4.1.71, MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN] +synonym: "UDP glucose-arylamine glucosyltransferase activity" EXACT [EC:2.4.1.71] +synonym: "UDP-glucose:arylamine N-D-glucosyltransferase activity" EXACT [EC:2.4.1.71] +synonym: "UDPglucose:arylamine N-D-glucosyltransferase activity" EXACT [EC:2.4.1.71] +synonym: "uridine diphosphoglucose-arylamine glucosyltransferase activity" EXACT [EC:2.4.1.71] +xref: EC:2.4.1.71 +xref: MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047685 +name: amine sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate." [EC:2.8.2.3, MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN] +synonym: "3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity" EXACT [EC:2.8.2.3] +synonym: "amine N-sulfotransferase activity" EXACT [EC:2.8.2.3] +synonym: "amine sulphotransferase activity" EXACT [] +synonym: "arylamine sulfotransferase activity" EXACT [] +xref: EC:2.8.2.3 +xref: MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047686 +name: arylsulfate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate." [EC:2.8.2.22, MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN] +synonym: "arylsulfate-phenol sulfotransferase activity" EXACT [EC:2.8.2.22] +synonym: "arylsulfate:phenol sulfotransferase activity" EXACT [EC:2.8.2.22] +synonym: "arylsulfotransferase" BROAD [EC:2.8.2.22] +synonym: "arylsulphate sulphotransferase activity" EXACT [] +synonym: "ASST" RELATED [EC:2.8.2.22] +xref: EC:2.8.2.22 +xref: MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047687 +name: obsolete ascorbate 2,3-dioxygenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: L-ascorbate + H(2)O + O(2) = L-threonate + 2 H(+) + oxalate." [EC:1.13.11.13, RHEA:21784] +comment: This term was made obsolete because EC:1.13.11.13 was deleted; the activity is the sum of several enzymatic and spontaneous reactions. +synonym: "AAoxygenase activity" EXACT [] +synonym: "ascorbate 2,3-dioxygenase activity" EXACT [] +synonym: "ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)" EXACT [] +xref: KEGG_REACTION:R00646 +xref: MetaCyc:ASCORBATE-23-DIOXYGENASE-RXN +xref: RHEA:21784 +is_obsolete: true + +[Term] +id: GO:0047688 +name: aspartate 4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate = L-alanine + CO2." [EC:4.1.1.12, MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN] +synonym: "aminomalonic decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "aspartate beta-decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "aspartate omega-decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "aspartic beta-decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "aspartic omega-decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "cysteine sulfinic desulfinase activity" EXACT [EC:4.1.1.12] +synonym: "desulfinase activity" EXACT [EC:4.1.1.12] +synonym: "L-aspartate 4-carboxy-lyase (L-alanine-forming)" EXACT [EC:4.1.1.12] +synonym: "L-aspartate 4-carboxy-lyase activity" EXACT [EC:4.1.1.12] +synonym: "L-aspartate beta-decarboxylase activity" EXACT [EC:4.1.1.12] +synonym: "L-cysteine sulfinate acid desulfinase activity" EXACT [EC:4.1.1.12] +xref: EC:4.1.1.12 +xref: MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN +xref: RHEA:12621 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047689 +name: aspartate racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-aspartate = D-aspartate." [EC:5.1.1.13, RHEA:14973] +synonym: "D-aspartate racemase activity" EXACT [EC:5.1.1.13] +xref: EC:5.1.1.13 +xref: KEGG_REACTION:R00491 +xref: MetaCyc:ASPARTATE-RACEMASE-RXN +xref: RHEA:14973 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0047690 +name: aspartyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+)." [EC:2.3.2.7, RHEA:11252] +synonym: "aspartotransferase activity" EXACT [EC:2.3.2.7] +synonym: "beta-aspartyl transferase activity" EXACT [EC:2.3.2.7] +synonym: "L-asparagine:hydroxylamine gamma-aspartyltransferase activity" EXACT [EC:2.3.2.7] +xref: EC:2.3.2.7 +xref: KEGG_REACTION:R01485 +xref: MetaCyc:ASPARTYLTRANSFERASE-RXN +xref: RHEA:11252 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0047691 +name: aspulvinone dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate." [EC:2.5.1.35, RHEA:13809] +synonym: "dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity" EXACT [EC:2.5.1.35] +synonym: "dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity" EXACT [EC:2.5.1.35] +xref: EC:2.5.1.35 +xref: KEGG_REACTION:R03799 +xref: MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN +xref: RHEA:13809 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047692 +name: ATP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ITP + NH3." [EC:3.5.4.18, MetaCyc:ATP-DEAMINASE-RXN] +synonym: "adenosine triphosphate deaminase activity" EXACT [EC:3.5.4.18] +synonym: "ATP aminohydrolase activity" EXACT [EC:3.5.4.18] +xref: EC:3.5.4.18 +xref: MetaCyc:ATP-DEAMINASE-RXN +xref: RHEA:13037 +is_a: GO:0047623 ! adenosine-phosphate deaminase activity + +[Term] +id: GO:0047693 +name: ATP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = AMP + diphosphate." [RHEA:14245] +synonym: "adenosine triphosphate pyrophosphatase activity" EXACT [EC:3.6.1.8] +synonym: "ATP diphosphohydrolase" BROAD [EC:3.6.1.8] +synonym: "ATP diphosphohydrolase (diphosphate-forming)" EXACT [EC:3.6.1.8] +synonym: "ATP pyrophosphatase activity" EXACT [] +xref: EC:3.6.1.8 +xref: MetaCyc:ATP-PYROPHOSPHATASE-RXN +xref: RHEA:14245 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity + +[Term] +id: GO:0047694 +name: barbiturase activity +namespace: molecular_function +def: "Catalysis of the reaction: barbiturate + H2O = malonate + urea." [EC:3.5.2.1, MetaCyc:BARBITURASE-RXN] +synonym: "barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming)" EXACT [EC:3.5.2.1] +xref: EC:3.5.2.1 +xref: MetaCyc:BARBITURASE-RXN +xref: RHEA:18653 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0047695 +name: benzoin aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoin = 2 benzaldehyde." [EC:4.1.2.38, RHEA:21460] +synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity" EXACT [EC:4.1.2.38] +synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)" EXACT [EC:4.1.2.38] +synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity" EXACT [EC:4.1.2.38] +synonym: "benzaldehyde lyase activity" EXACT [EC:4.1.2.38] +synonym: "diphenylethanone benzaldehyde-lyase activity" EXACT [EC:4.1.2.38] +xref: EC:4.1.2.38 +xref: KEGG_REACTION:R00027 +xref: MetaCyc:BENZOIN-ALDOLASE-RXN +xref: RHEA:21460 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047696 +name: beta-adrenergic receptor kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor." [EC:2.7.11.15, MetaCyc:BETA-ADRENERGIC-RECEPTOR-KINASE-RXN] +synonym: "[b-adrenergic-receptor] kinase activity" EXACT [EC:2.7.11.15] +synonym: "ADRBK1" RELATED [EC:2.7.11.15] +synonym: "adrenergic receptor kinase activity" BROAD [EC:2.7.11.15] +synonym: "ATP:beta-adrenergic-receptor phosphotransferase activity" BROAD [EC:2.7.11.15] +synonym: "BARK1" RELATED [EC:2.7.11.15] +synonym: "beta-adrenergic receptor-specific kinase activity" EXACT [EC:2.7.11.15] +synonym: "beta-adrenergic-receptor kinase (phosphorylating) activity" EXACT [EC:2.7.11.15] +synonym: "beta-adrenergic-receptor kinase activity" EXACT [EC:2.7.11.15] +synonym: "beta-adrenoceptor kinase 1 activity" NARROW [EC:2.7.11.15] +synonym: "beta-adrenoceptor kinase 2 activity" NARROW [EC:2.7.11.15] +synonym: "beta-adrenoceptor kinase activity" EXACT [EC:2.7.11.15] +synonym: "beta-AR kinase activity" EXACT [EC:2.7.11.15] +synonym: "beta-ARK" RELATED [EC:2.7.11.15] +synonym: "beta-ARK 1" RELATED [EC:2.7.11.15] +synonym: "beta-ARK 2" RELATED [EC:2.7.11.15] +synonym: "beta-receptor kinase activity" EXACT [EC:2.7.11.15] +synonym: "beta2ARK" RELATED [EC:2.7.11.15] +synonym: "betaARK1" RELATED [EC:2.7.11.15] +synonym: "GRK2" RELATED [EC:2.7.11.15] +synonym: "GRK3" RELATED [EC:2.7.11.15] +synonym: "STK15" RELATED [EC:2.7.11.15] +xref: EC:2.7.11.15 +xref: Reactome:R-HSA-8851797 "ADRB2 in ADRB2:GRK complex is phosphorylated" +xref: Reactome:R-HSA-8866268 "ADBRK1,2 phosphorylate AVPR2" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0047697 +name: beta-alanopine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate." [EC:1.5.1.26, RHEA:21684] +synonym: "b-alanopine dehydrogenase activity" EXACT [] +synonym: "N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming)" EXACT [EC:1.5.1.26] +xref: EC:1.5.1.26 +xref: KEGG_REACTION:R00906 +xref: MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN +xref: RHEA:21684 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047698 +name: beta-alanyl-CoA ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3." [EC:4.3.1.6, MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN] +synonym: "b-alanyl-CoA ammonia-lyase activity" EXACT [] +synonym: "beta-alanyl coenzyme A ammonia-lyase activity" EXACT [EC:4.3.1.6] +synonym: "beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)" EXACT [EC:4.3.1.6] +xref: EC:4.3.1.6 +xref: MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN +xref: RHEA:12416 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0047699 +name: beta-diketone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one." [EC:3.7.1.7, RHEA:11908] +synonym: "b-diketone hydrolase activity" EXACT [] +synonym: "nonane-4,6-dione acylhydrolase activity" EXACT [EC:3.7.1.7] +synonym: "oxidized PVA hydrolase activity" EXACT [EC:3.7.1.7] +xref: EC:3.7.1.7 +xref: KEGG_REACTION:R03781 +xref: MetaCyc:BETA-DIKETONE-HYDROLASE-RXN +xref: RHEA:11908 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0047700 +name: beta-glucoside kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose." [EC:2.7.1.85, MetaCyc:BETA-GLUCOSIDE-KINASE-RXN] +synonym: "ATP:cellobiose 6-phosphotransferase activity" EXACT [EC:2.7.1.85] +synonym: "b-glucoside kinase activity" EXACT [] +synonym: "beta-D-glucoside kinase (phosphorylating)" EXACT [EC:2.7.1.85] +xref: EC:2.7.1.85 +xref: MetaCyc:BETA-GLUCOSIDE-KINASE-RXN +xref: RHEA:21944 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047701 +name: beta-L-arabinosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol." [EC:3.2.1.88, MetaCyc:BETA-L-ARABINOSIDASE-RXN] +synonym: "b-L-arabinosidase activity" EXACT [] +synonym: "beta-L-arabinoside arabinohydrolase activity" EXACT [EC:3.2.1.88] +synonym: "vicianosidase activity" EXACT [EC:3.2.1.88] +xref: EC:3.2.1.88 +xref: MetaCyc:BETA-L-ARABINOSIDASE-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047702 +name: beta-lysine 5,6-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate." [EC:5.4.3.3, RHEA:21736] +synonym: "(3S)-3,6-diaminohexanoate 5,6-aminomutase activity" EXACT [EC:5.4.3.3] +synonym: "b-lysine 5,6-aminomutase activity" EXACT [] +synonym: "beta-lysine mutase activity" EXACT [EC:5.4.3.3] +synonym: "L-beta-lysine 5,6-aminomutase activity" EXACT [EC:5.4.3.3] +xref: EC:5.4.3.3 +xref: KEGG_REACTION:R03275 +xref: MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN +xref: RHEA:21736 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0047703 +name: beta-nitroacrylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH." [EC:1.3.1.16, RHEA:23892] +synonym: "3-nitropropanoate:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.16] +synonym: "b-nitroacrylate reductase activity" EXACT [] +xref: EC:1.3.1.16 +xref: KEGG_REACTION:R03900 +xref: MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN +xref: RHEA:23892 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047704 +name: bile-salt sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate." [EC:2.8.2.14, MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN] +subset: goslim_chembl +synonym: "3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity" EXACT [EC:2.8.2.14] +synonym: "BAST I activity" NARROW [EC:2.8.2.14] +synonym: "bile acid sulfotransferase I activity" NARROW [EC:2.8.2.14] +synonym: "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity" EXACT [EC:2.8.2.14] +synonym: "bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity" EXACT [EC:2.8.2.14] +synonym: "bile-salt sulphotransferase activity" EXACT [] +synonym: "glycolithocholate sulfotransferase activity" NARROW [EC:2.8.2.14] +xref: EC:2.8.2.14 +xref: MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047705 +name: bilirubin oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O." [EC:1.3.3.5, RHEA:20980] +synonym: "bilirubin oxidase M-1" RELATED [EC:1.3.3.5] +synonym: "bilirubin:oxygen oxidoreductase activity" EXACT [EC:1.3.3.5] +xref: EC:1.3.3.5 +xref: KEGG_REACTION:R02394 +xref: MetaCyc:BILIRUBIN-OXIDASE-RXN +xref: RHEA:20980 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0047706 +name: biochanin-A reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH." [EC:1.3.1.46, RHEA:12817] +synonym: "dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.46] +xref: EC:1.3.1.46 +xref: KEGG_REACTION:R02954 +xref: MetaCyc:BIOCHANIN-A-REDUCTASE-RXN +xref: RHEA:12817 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047707 +name: biotin-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA." [EC:6.2.1.11, MetaCyc:BIOTIN--COA-LIGASE-RXN] +synonym: "biotin CoA synthetase activity" EXACT [EC:6.2.1.11] +synonym: "biotin:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.11] +synonym: "biotinyl coenzyme A synthetase activity" EXACT [EC:6.2.1.11] +synonym: "biotinyl-CoA synthetase activity" EXACT [EC:6.2.1.11] +xref: EC:6.2.1.11 +xref: MetaCyc:BIOTIN--COA-LIGASE-RXN +xref: RHEA:19681 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047708 +name: biotinidase activity +namespace: molecular_function +def: "Catalysis of the reaction: biotin amide + H2O = biotin + NH3." [EC:3.5.1.12, MetaCyc:BIOTINIDASE-RXN] +synonym: "amidohydrolase biotinidase activity" EXACT [EC:3.5.1.12] +synonym: "biotin-amide amidohydrolase activity" EXACT [EC:3.5.1.12] +xref: EC:3.5.1.12 +xref: MetaCyc:BIOTINIDASE-RXN +xref: Reactome:R-HSA-3076905 "Extracellular BTD hydrolyses BCTN" +xref: Reactome:R-HSA-3325540 "Defective extracellular BTD does not hydrolyse BCTN" +xref: Reactome:R-HSA-4167509 "Mitochondrial BTD hydrolyses BCTN" +xref: Reactome:R-HSA-4225086 "Defective mitochondrial BTD does not hydrolyse BCTN" +xref: RHEA:13081 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047709 +name: bis(2-ethylhexyl)phthalate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+)." [EC:3.1.1.60, RHEA:15529] +synonym: "bis(2-ethylhexyl)phthalate acylhydrolase activity" EXACT [EC:3.1.1.60] +synonym: "DEHP esterase activity" EXACT [EC:3.1.1.60] +xref: EC:3.1.1.60 +xref: KEGG_REACTION:R04202 +xref: MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN +xref: RHEA:15529 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047710 +name: bis(5'-adenosyl)-triphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+)." [EC:3.6.1.29, RHEA:13893] +synonym: "1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity" EXACT [EC:3.6.1.29] +synonym: "AP(3)A hydrolase activity" EXACT [EC:3.6.1.29] +synonym: "AP(3)Aase activity" EXACT [EC:3.6.1.29] +synonym: "AP3A hydrolase activity" EXACT [EC:3.6.1.29] +synonym: "AP3Aase activity" EXACT [EC:3.6.1.29] +synonym: "diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity" EXACT [EC:3.6.1.29] +synonym: "diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity" EXACT [EC:3.6.1.29] +synonym: "diadenosine 5,5-P1,P3-triphosphatase activity" EXACT [EC:3.6.1.29] +synonym: "dinucleosidetriphosphatase activity" EXACT [EC:3.6.1.29] +synonym: "P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity" EXACT [EC:3.6.1.29] +xref: EC:3.6.1.29 +xref: KEGG_REACTION:R00187 +xref: MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN +xref: RHEA:13893 +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0047711 +name: blasticidin-S deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3." [EC:3.5.4.23, MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN] +synonym: "blasticidin-S aminohydrolase activity" EXACT [EC:3.5.4.23] +xref: EC:3.5.4.23 +xref: MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN +xref: RHEA:10148 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047712 +name: Cypridina-luciferin 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light." [EC:1.13.12.6, MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN] +synonym: "Cypridina luciferase activity" EXACT [EC:1.13.12.6] +synonym: "Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.6] +synonym: "Cypridina-type luciferase activity" EXACT [EC:1.13.12.6] +synonym: "luciferase (Cypridina luciferin)" EXACT [EC:1.13.12.6] +synonym: "luciferase activity" BROAD [EC:1.13.12.6] +xref: EC:1.13.12.6 +xref: MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN +xref: RHEA:22760 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0047713 +name: galactitol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH." [EC:1.1.1.16, RHEA:20685] +xref: EC:1.1.1.16 +xref: KEGG_REACTION:R02928 +xref: MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN +xref: RHEA:20685 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +is_a: GO:0031320 ! hexitol dehydrogenase activity + +[Term] +id: GO:0047714 +name: galactolipase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates." [EC:3.1.1.26, MetaCyc:GALACTOLIPASE-RXN] +synonym: "1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity" EXACT [EC:3.1.1.26] +synonym: "galactolipid acylhydrolase activity" EXACT [EC:3.1.1.26] +synonym: "galactolipid lipase activity" EXACT [EC:3.1.1.26] +synonym: "polygalactolipase activity" EXACT [EC:3.1.1.26] +xref: EC:3.1.1.26 +xref: MetaCyc:GALACTOLIPASE-RXN +xref: RHEA:13189 +is_a: GO:0016298 ! lipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047715 +name: hypotaurocyamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+)." [EC:2.7.3.6, RHEA:24008] +synonym: "ATP:hypotaurocyamine N-phosphotransferase activity" EXACT [EC:2.7.3.6] +xref: EC:2.7.3.6 +xref: KEGG_REACTION:R03939 +xref: MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN +xref: RHEA:24008 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0047716 +name: imidazole N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA." [EC:2.3.1.2, RHEA:15813] +synonym: "acetyl-CoA:imidazole N-acetyltransferase activity" EXACT [EC:2.3.1.2] +synonym: "imidazole acetylase activity" EXACT [EC:2.3.1.2] +synonym: "imidazole acetyltransferase activity" EXACT [EC:2.3.1.2] +xref: EC:2.3.1.2 +xref: KEGG_REACTION:R03621 +xref: MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:15813 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047717 +name: imidazoleacetate 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+)." [EC:1.14.13.5, RHEA:19425] +synonym: "4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.13.5] +synonym: "imidazoleacetate hydroxylase activity" EXACT [EC:1.14.13.5] +synonym: "imidazoleacetic hydroxylase activity" EXACT [] +synonym: "imidazoleacetic monooxygenase activity" EXACT [EC:1.14.13.5] +xref: EC:1.14.13.5 +xref: KEGG_REACTION:R04066 +xref: MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN +xref: RHEA:19425 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047718 +name: indanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+." [EC:1.1.1.112, MetaCyc:INDANOL-DEHYDROGENASE-RXN] +synonym: "indan-1-ol:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.112] +xref: EC:1.1.1.112 +xref: MetaCyc:INDANOL-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047719 +name: indole 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde." [EC:1.13.11.17, RHEA:11212] +synonym: "IDO" RELATED [EC:1.13.11.17] +synonym: "indole oxidase activity" EXACT [EC:1.13.11.17] +synonym: "indole-oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.17] +synonym: "indole:O2 oxidoreductase activity" EXACT [EC:1.13.11.17] +synonym: "indole:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.17] +xref: EC:1.13.11.17 +xref: KEGG_REACTION:R02338 +xref: MetaCyc:INDOLE-23-DIOXYGENASE-RXN +xref: RHEA:11212 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047720 +name: indoleacetaldoxime dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O." [EC:4.99.1.6, RHEA:23156] +synonym: "(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]" RELATED [EC:4.99.1.6] +synonym: "(indol-3-yl)acetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.6] +synonym: "3-indoleacetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] +synonym: "indole-3-acetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.6] +synonym: "indole-3-acetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] +synonym: "indoleacetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] +xref: EC:4.99.1.6 +xref: KEGG_REACTION:R04093 +xref: MetaCyc:RXN-1403 +xref: RHEA:23156 +is_a: GO:0016829 ! lyase activity + +[Term] +id: GO:0047721 +name: indoleacetate-lysine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate." [EC:6.3.2.20, RHEA:14857] +synonym: "(indol-3-yl)acetate:L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.20] +synonym: "IAA-lysine synthetase activity" EXACT [EC:6.3.2.20] +synonym: "indoleacetate-lysine ligase activity" EXACT [] +synonym: "indoleacetate:L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.20] +synonym: "N-(indole-3-acetyl)-L-lysine synthetase activity" EXACT [EC:6.3.2.20] +xref: EC:6.3.2.20 +xref: KEGG_REACTION:R03095 +xref: MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN +xref: RHEA:14857 +is_a: GO:0010279 ! indole-3-acetic acid amido synthetase activity + +[Term] +id: GO:0047722 +name: indolelactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH." [EC:1.1.1.110, RHEA:20133] +synonym: "(indol-3-yl)lactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.110] +synonym: "indole-3-lactate dehydrogenase activity" EXACT [] +synonym: "indolelactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.110] +xref: EC:1.1.1.110 +xref: KEGG_REACTION:R01971 +xref: MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN +xref: RHEA:20133 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047723 +name: inosinate nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine." [EC:3.2.2.12, RHEA:20469] +synonym: "5'-inosinate phosphoribohydrolase activity" EXACT [EC:3.2.2.12] +xref: EC:3.2.2.12 +xref: KEGG_REACTION:R01128 +xref: MetaCyc:INOSINATE-NUCLEOSIDASE-RXN +xref: RHEA:20469 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0047724 +name: inosine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine." [EC:3.2.2.2, MetaCyc:INOSINE-NUCLEOSIDASE-RXN] +synonym: "inosinase activity" EXACT [EC:3.2.2.2] +synonym: "inosine ribohydrolase activity" EXACT [EC:3.2.2.2] +synonym: "inosine-guanosine nucleosidase activity" EXACT [EC:3.2.2.2] +xref: EC:3.2.2.2 +xref: MetaCyc:INOSINE-NUCLEOSIDASE-RXN +xref: RHEA:16657 +is_a: GO:0008477 ! purine nucleosidase activity + +[Term] +id: GO:0047725 +name: inulosucrase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1)." [EC:2.4.1.9, MetaCyc:INULOSUCRASE-RXN] +synonym: "sucrose 1-fructosyl transferase activity" EXACT [EC:2.4.1.9] +synonym: "sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.9] +synonym: "sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.9] +xref: EC:2.4.1.9 +xref: MetaCyc:INULOSUCRASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047726 +name: iron-cytochrome-c reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+." [EC:1.9.98.1, MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN] +synonym: "ferrocytochrome-c:Fe3+ oxidoreductase activity" EXACT [EC:1.9.98.1] +synonym: "iron-cytochrome c reductase activity" EXACT [EC:1.9.98.1] +xref: EC:1.9.98.1 +xref: MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN +xref: RHEA:15617 +is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors + +[Term] +id: GO:0047727 +name: isobutyryl-CoA mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA." [EC:5.4.99.13, RHEA:13141] +synonym: "2-methylpropanoyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.13] +synonym: "butyryl-CoA:isobutyryl-CoA mutase activity" EXACT [EC:5.4.99.13] +synonym: "isobutyryl coenzyme A mutase activity" EXACT [EC:5.4.99.13] +xref: EC:5.4.99.13 +xref: KEGG_REACTION:R01181 +xref: MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN +xref: RHEA:13141 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0047728 +name: carnitine 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH." [EC:1.1.1.108, RHEA:19265] +synonym: "carnitine:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.108] +xref: EC:1.1.1.108 +xref: KEGG_REACTION:R02395 +xref: MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN +xref: RHEA:19265 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047729 +name: carnitine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2)." [EC:4.1.1.42, RHEA:21576] +synonym: "carnitine carboxy-lyase (2-methylcholine-forming)" EXACT [EC:4.1.1.42] +synonym: "carnitine carboxy-lyase activity" EXACT [EC:4.1.1.42] +xref: EC:4.1.1.42 +xref: KEGG_REACTION:R02398 +xref: MetaCyc:CARNITINE-DECARBOXYLASE-RXN +xref: RHEA:21576 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047730 +name: carnosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine." [EC:6.3.2.11, MetaCyc:CARNOSINE-SYNTHASE-RXN] +synonym: "carnosine synthetase activity" EXACT [EC:6.3.2.11] +synonym: "carnosine-anserine synthetase activity" EXACT [EC:6.3.2.11] +synonym: "carnosine-homocarnosine synthetase activity" EXACT [EC:6.3.2.11] +synonym: "homocarnosine-carnosine synthetase activity" EXACT [EC:6.3.2.11] +synonym: "L-histidine:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.11] +xref: EC:6.3.2.11 +xref: MetaCyc:CARNOSINE-SYNTHASE-RXN +xref: Reactome:R-HSA-6786245 "CARNS1 transforms ATP, L-His, b-Ala to CARN" +xref: RHEA:19297 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047731 +name: catechol oxidase (dimerizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O." [EC:1.1.3.14, MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN] +synonym: "catechol:oxygen oxidoreductase (dimerizing)" EXACT [EC:1.1.3.14] +xref: EC:1.1.3.14 +xref: MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN +xref: RHEA:12809 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047732 +name: CDP-abequose epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose." [EC:5.1.3.10, RHEA:21656] +synonym: "CDP-3,6-dideoxy-D-glucose 2-epimerase activity" EXACT [EC:5.1.3.10] +synonym: "CDP-D-abequose 2-epimerase activity" EXACT [EC:5.1.3.10] +synonym: "CDP-paratose 2-epimerase activity" EXACT [EC:5.1.3.10] +synonym: "CDP-paratose epimerase activity" EXACT [EC:5.1.3.10] +synonym: "CDP-tyvelose 2-epimerase activity" EXACT [EC:5.1.3.10] +synonym: "cytidine diphosphate paratose-2-epimerase activity" EXACT [EC:5.1.3.10] +synonym: "cytidine diphosphoabequose epimerase activity" EXACT [EC:5.1.3.10] +synonym: "cytidine diphosphodideoxyglucose epimerase activity" EXACT [EC:5.1.3.10] +synonym: "cytidine diphosphoparatose epimerase activity" EXACT [EC:5.1.3.10] +xref: EC:5.1.3.10 +xref: KEGG_REACTION:R04266 +xref: MetaCyc:RXN-9160 +xref: RHEA:21656 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047733 +name: CDP-glucose 4,6-dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O." [EC:4.2.1.45, RHEA:17153] +synonym: "CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.45] +synonym: "CDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.45] +synonym: "CDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.45] +synonym: "CDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.45] +synonym: "cytidine diphosphoglucose oxidoreductase activity" EXACT [EC:4.2.1.45] +xref: EC:4.2.1.45 +xref: KEGG_REACTION:R02426 +xref: MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN +xref: RHEA:17153 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047734 +name: CDP-glycerol diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+)." [EC:3.6.1.16, RHEA:21692] +synonym: "CDP-glycerol phosphoglycerohydrolase activity" EXACT [EC:3.6.1.16] +synonym: "CDP-glycerol pyrophosphatase activity" EXACT [] +synonym: "CDPglycerol diphosphatase activity" EXACT [EC:3.6.1.16] +synonym: "CDPglycerol phosphoglycerohydrolase activity" EXACT [EC:3.6.1.16] +synonym: "CDPglycerol pyrophosphatase activity" EXACT [EC:3.6.1.16] +synonym: "cytidine diphosphoglycerol pyrophosphatase activity" EXACT [EC:3.6.1.16] +xref: EC:3.6.1.16 +xref: KEGG_REACTION:R00855 +xref: MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN +xref: RHEA:21692 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047735 +name: cellobiose dehydrogenase (acceptor) activity +namespace: molecular_function +alt_id: GO:0047737 +def: "Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor." [EC:1.1.99.18, MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN] +synonym: "CBOR activity" RELATED [EC:1.1.99.18] +synonym: "CDH activity" RELATED [EC:1.1.99.18] +synonym: "cellobiose dehydrogenase (quinone) activity" NARROW [EC:1.1.99.18] +synonym: "cellobiose dehydrogenase activity" EXACT [EC:1.1.99.18] +synonym: "cellobiose oxidase activity" EXACT [EC:1.1.99.18] +synonym: "cellobiose oxidoreductase activity" EXACT [EC:1.1.99.18] +synonym: "cellobiose-quinone oxidoreductase activity" NARROW [EC:1.1.99.18] +synonym: "cellobiose:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.18] +synonym: "cellobiose:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.18] +synonym: "cellobiose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.99.18] +synonym: "phanerochaete chrysosporium cellobiose oxidoreductase activity" EXACT [EC:1.1.99.18] +xref: EC:1.1.99.18 +xref: MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN +xref: RHEA:23484 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047736 +name: cellobiose epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose." [EC:5.1.3.11, MetaCyc:CELLOBIOSE-EPIMERASE-RXN] +synonym: "cellobiose 2-epimerase activity" EXACT [EC:5.1.3.11] +xref: EC:5.1.3.11 +xref: MetaCyc:CELLOBIOSE-EPIMERASE-RXN +xref: RHEA:23384 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047738 +name: cellobiose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose." [EC:2.4.1.20, MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN] +synonym: "cellobiose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.20] +xref: EC:2.4.1.20 +xref: MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN +xref: RHEA:19493 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0047739 +name: cephalosporin-C deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+)." [EC:3.1.1.41, RHEA:22596] +synonym: "cephalosporin acetylesterase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin C acetyl-esterase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin C acetyl-hydrolase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin C acetylase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin C acetylesterase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin C deacetylase activity" EXACT [EC:3.1.1.41] +synonym: "cephalosporin-C acetylhydrolase activity" EXACT [EC:3.1.1.41] +xref: EC:3.1.1.41 +xref: KEGG_REACTION:R03062 +xref: MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN +xref: RHEA:22596 +is_a: GO:0019213 ! deacetylase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047740 +name: cephalosporin-C transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C." [EC:2.6.1.74, RHEA:14553] +synonym: "cephalosporin C aminotransferase activity" EXACT [EC:2.6.1.74] +synonym: "cephalosporin-C:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.74] +synonym: "L-alanine:cephalosporin-C aminotransferase activity" EXACT [EC:2.6.1.74] +xref: EC:2.6.1.74 +xref: KEGG_REACTION:R03063 +xref: MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN +xref: RHEA:14553 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047741 +name: cetraxate benzylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+)." [EC:3.1.1.70, RHEA:23460] +synonym: "cetraxate-benzyl-ester benzylhydrolase activity" EXACT [EC:3.1.1.70] +xref: EC:3.1.1.70 +xref: KEGG_REACTION:R03612 +xref: MetaCyc:CETRAXATE-BENZYLESTERASE-RXN +xref: RHEA:23460 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047742 +name: chenodeoxycholoyltaurine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine." [EC:3.5.1.74, MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN] +synonym: "chenodeoxycholoyltaurine amidohydrolase activity" EXACT [EC:3.5.1.74] +xref: EC:3.5.1.74 +xref: MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN +xref: RHEA:16309 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047743 +name: chlordecone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH." [EC:1.1.1.225, RHEA:14401] +synonym: "CDR activity" RELATED [EC:1.1.1.225] +synonym: "chlordecone-alcohol:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.225] +xref: EC:1.1.1.225 +xref: KEGG_REACTION:R03716 +xref: MetaCyc:CHLORDECONE-REDUCTASE-RXN +xref: RHEA:14401 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047744 +name: chloridazon-catechol dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)." [EC:1.13.11.36, RHEA:20449] +synonym: "5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.36] +xref: EC:1.13.11.36 +xref: KEGG_REACTION:R04602 +xref: MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN +xref: RHEA:20449 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047745 +name: chlorogenate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+)." [EC:3.1.1.42, RHEA:20689] +synonym: "chlorogenase activity" EXACT [EC:3.1.1.42] +synonym: "chlorogenic acid esterase activity" EXACT [EC:3.1.1.42] +xref: EC:3.1.1.42 +xref: KEGG_REACTION:R02997 +xref: MetaCyc:CHLOROGENATE-HYDROLASE-RXN +xref: RHEA:20689 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047746 +name: chlorophyllase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide." [EC:3.1.1.14, MetaCyc:CHLOROPHYLLASE-RXN] +synonym: "chlorophyll chlorophyllidohydrolase activity" EXACT [EC:3.1.1.14] +xref: EC:3.1.1.14 +xref: MetaCyc:CHLOROPHYLLASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047747 +name: cholate-CoA ligase activity +namespace: molecular_function +alt_id: GO:0047477 +def: "Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA." [EC:6.2.1.7, MetaCyc:CHOLATE--COA-LIGASE-RXN] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity" EXACT [EC:6.2.1.29] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity" EXACT [] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity" EXACT [EC:6.2.1.29] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity" EXACT [EC:6.2.1.29] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity" EXACT [EC:6.2.1.29] +synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity" EXACT [EC:6.2.1.29] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.29] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity" EXACT [EC:6.2.1.29] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity" EXACT [EC:6.2.1.29] +synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] +synonym: "BAL activity" RELATED [EC:6.2.1.29] +synonym: "bile acid CoA ligase activity" RELATED [EC:6.2.1.29] +synonym: "bile acid coenzyme A ligase activity" RELATED [EC:6.2.1.29] +synonym: "cholate thiokinase activity" EXACT [EC:6.2.1.29] +synonym: "cholate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.29] +synonym: "cholic acid:CoA ligase activity" EXACT [EC:6.2.1.29] +synonym: "cholic thiokinase activity" EXACT [EC:6.2.1.29] +synonym: "choloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] +synonym: "choloyl-CoA synthetase activity" EXACT [EC:6.2.1.29] +synonym: "cholyl-CoA synthetase activity" EXACT [EC:6.2.1.29] +synonym: "THCA-CoA ligase activity" RELATED [EC:6.2.1.29] +synonym: "trihydroxycoprostanoyl-CoA synthetase activity" RELATED [EC:6.2.1.29] +xref: EC:6.2.1.7 +xref: MetaCyc:CHOLATE--COA-LIGASE-RXN +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047748 +name: cholestanetetraol 26-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH." [MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN, RHEA:34631] +synonym: "5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity" EXACT [] +synonym: "5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity" EXACT [] +synonym: "cholestanetetrol 26-dehydrogenase activity" EXACT [] +synonym: "TEHC-NAD oxidoreductase activity" EXACT [] +xref: MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN +xref: RHEA:34631 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047749 +name: cholestanetriol 26-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O." [EC:1.14.15.15, MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN] +synonym: "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity" EXACT [EC:1.14.15.15] +synonym: "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity" BROAD [EC:1.14.15.15] +synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity" EXACT [EC:1.14.15.15] +synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity" EXACT [EC:1.14.15.15] +synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)" EXACT [EC:1.14.15.15] +synonym: "cholestanetriol 26-hydroxylase activity" EXACT [EC:1.14.15.15] +synonym: "cholesterol 27-hydroxylase activity" RELATED [EC:1.14.15.15] +synonym: "CYP27A" RELATED [] +synonym: "CYP27A1" RELATED [] +synonym: "cytochrome P450 27A1' activity" NARROW [EC:1.14.15.15] +synonym: "sterol 26-hydroxylase activity" BROAD [EC:1.14.15.15] +synonym: "sterol 27-hydroxylase activity" RELATED [EC:1.14.15.15] +xref: EC:1.14.15.15 +xref: MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN +xref: RHEA:14373 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047750 +name: cholestenol delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol." [EC:5.3.3.5, MetaCyc:CHOLESTENOL-DELTA-ISOMERASE-RXN] +synonym: "cholestenol D-isomerase activity" EXACT [] +synonym: "delta7-cholestenol delta7-delta8-isomerase activity" EXACT [EC:5.3.3.5] +xref: EC:5.3.3.5 +xref: MetaCyc:RXN66-25 +xref: RHEA:15281 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0047751 +name: cholestenone 5-alpha-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH." [EC:1.3.1.22, RHEA:24552] +synonym: "3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.22] +synonym: "3-oxosteroid 5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "3-oxosteroid delta4-dehydrogenase" BROAD [EC:1.3.1.22] +synonym: "4-ene-3-oxosteroid 5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "4-ene-5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "5alpha-reductase" BROAD [EC:1.3.1.22] +synonym: "cholest-4-en-3-one 5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "cholestenone 5a-reductase activity" EXACT [] +synonym: "cholestenone 5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "delta4-3-ketosteroid 5alpha-oxidoreductase activity" EXACT [EC:1.3.1.22] +synonym: "reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity" EXACT [EC:1.3.1.22] +synonym: "steroid 5alpha-hydrogenase activity" EXACT [EC:1.3.1.22] +synonym: "steroid 5alpha-reductase" BROAD [EC:1.3.1.22] +synonym: "testosterone 5alpha-reductase" BROAD [EC:1.3.1.22] +synonym: "testosterone delta4-5alpha-reductase activity" EXACT [EC:1.3.1.22] +synonym: "testosterone delta4-hydrogenase activity" EXACT [EC:1.3.1.22] +xref: EC:1.3.1.22 +xref: KEGG_REACTION:R02610 +xref: MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN +xref: RHEA:24552 +is_a: GO:0035671 ! enone reductase activity + +[Term] +id: GO:0047753 +name: choline-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate." [EC:3.1.6.6, RHEA:20820] +synonym: "choline-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.6] +synonym: "choline-sulphatase activity" EXACT [] +xref: EC:3.1.6.6 +xref: KEGG_REACTION:R01028 +xref: MetaCyc:CHOLINE-SULFATASE-RXN +xref: RHEA:20820 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0047754 +name: choline sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+)." [EC:2.8.2.6, RHEA:21984] +synonym: "3'-phosphoadenylyl-sulfate:choline sulfotransferase activity" EXACT [EC:2.8.2.6] +synonym: "choline sulphokinase activity" EXACT [EC:2.8.2.6] +synonym: "choline sulphotransferase activity" EXACT [] +xref: EC:2.8.2.6 +xref: KEGG_REACTION:R01027 +xref: MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN +xref: RHEA:21984 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047755 +name: isocitrate epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate." [EC:5.1.2.6, RHEA:10820] +synonym: "(1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity" EXACT [EC:5.1.2.6] +xref: EC:5.1.2.6 +xref: KEGG_REACTION:R02318 +xref: MetaCyc:ISOCITRATE-EPIMERASE-RXN +xref: RHEA:10820 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0047756 +name: chondroitin 4-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate." [EC:2.8.2.5, MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN] +synonym: "3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity" EXACT [EC:2.8.2.5] +synonym: "chondroitin 4-sulphotransferase activity" EXACT [] +xref: EC:2.8.2.5 +xref: MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-1971483 "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13" +is_a: GO:0034481 ! chondroitin sulfotransferase activity + +[Term] +id: GO:0047757 +name: chondroitin-glucuronate 5-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate." [EC:5.1.3.19, MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN] +synonym: "chondroitin D-glucuronosyl 5-epimerase activity" EXACT [EC:5.1.3.19] +synonym: "chondroitin-D-glucuronate 5-epimerase activity" EXACT [EC:5.1.3.19] +synonym: "dermatan-sulfate 5-epimerase activity" EXACT [EC:5.1.3.19] +synonym: "polyglucuronate 5-epimerase activity" RELATED [EC:5.1.3.19] +synonym: "urunosyl C-5 epimerase activity" EXACT [EC:5.1.3.19] +xref: EC:5.1.3.19 +xref: MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN +xref: Reactome:R-HSA-2022052 "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)" +xref: RHEA:21084 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047758 +name: ATP:2-methylpropanoate phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+)." [EC:2.7.2.14, RHEA:24156] +synonym: "ATP:2-methylpropanoate 1-phosphotransferase activity" EXACT [] +synonym: "ATP:2-methylpropanoate kinase activity" EXACT [] +synonym: "ATP:branched-chain-fatty-acid 1-phosphotransferase activity" BROAD [EC:2.7.2.14, KEGG_REACTION:R04002] +synonym: "ATP:isobutyrate 1-phosphotransferase activity" EXACT [] +synonym: "branched-chain fatty acid kinase activity" BROAD [EC:2.7.2.14] +synonym: "branched-chain-fatty-acid kinase activity" BROAD [EC:2.7.2.14] +synonym: "isobutyrate kinase activity" BROAD [EC:2.7.2.14] +xref: EC:2.7.2.14 +xref: KEGG_REACTION:R04002 +xref: MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN +xref: RHEA:24156 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0047759 +name: butanal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+." [EC:1.2.1.57, MetaCyc:BUTANAL-DEHYDROGENASE-RXN] +synonym: "butanal:NAD(P)+ oxidoreductase (CoA-acylating)" EXACT [EC:1.2.1.57] +xref: EC:1.2.1.57 +xref: MetaCyc:BUTANAL-DEHYDROGENASE-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047760 +name: butyrate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA." [EC:6.2.1.2, MetaCyc:BUTYRATE--COA-LIGASE-RXN] +synonym: "acyl-activating enzyme activity" RELATED [EC:6.2.1.2] +synonym: "butanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.2] +synonym: "butyryl-CoA synthetase activity" EXACT [EC:6.2.1.2] +synonym: "butyryl-coenzyme A synthetase activity" EXACT [EC:6.2.1.2] +synonym: "fatty acid activating enzyme" RELATED [EC:6.2.1.2] +synonym: "fatty acid thiokinase (medium chain) activity" RELATED [EC:6.2.1.2] +synonym: "fatty acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.2] +synonym: "L-(+)-3-hydroxybutyryl CoA ligase activity" EXACT [EC:6.2.1.2] +synonym: "medium chain acyl-CoA synthetase activity" EXACT [EC:6.2.1.2] +synonym: "short-chain acyl-CoA synthetase activity" EXACT [EC:6.2.1.2] +xref: EC:6.2.1.2 +xref: MetaCyc:BUTYRATE--COA-LIGASE-RXN +xref: Reactome:R-HSA-8875013 "ACSM3,ACSM6 ligate CoA to BUT" +xref: RHEA:24336 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047761 +name: butyrate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+)." [EC:2.7.2.7, RHEA:13585] +synonym: "ATP:butanoate 1-phosphotransferase activity" EXACT [EC:2.7.2.7] +xref: EC:2.7.2.7 +xref: KEGG_REACTION:R01688 +xref: MetaCyc:BUTYRATE-KINASE-RXN +xref: RHEA:13585 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0047762 +name: caffeate 3,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+)." [EC:1.13.11.22, RHEA:22216] +synonym: "3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.22] +xref: EC:1.13.11.22 +xref: KEGG_REACTION:R03365 +xref: MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN +xref: RHEA:22216 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047763 +name: caffeate O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate." [EC:2.1.1.68, MetaCyc:CAFFEATE-O-METHYLTRANSFERASE-RXN] +synonym: "caffeate 3-O-methyltransferase activity" EXACT [EC:2.1.1.68] +synonym: "caffeate methyltransferase activity" EXACT [EC:2.1.1.68] +synonym: "S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity" EXACT [EC:2.1.1.68] +synonym: "S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity" EXACT [EC:2.1.1.68] +xref: EC:2.1.1.68 +xref: MetaCyc:RXN-1104 +xref: RHEA:20225 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0047764 +name: obsolete caldesmon kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate." [GOC:curators] +comment: This term was made obsolete because it represents a specific gene product. +xref: MetaCyc:2.7.11.17-RXN +is_obsolete: true + +[Term] +id: GO:0047765 +name: caldesmon-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate." [EC:3.1.3.55, MetaCyc:CALDESMON-PHOSPHATASE-RXN] +synonym: "caldesmon-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.55] +synonym: "smooth muscle caldesmon phosphatase activity" EXACT [EC:3.1.3.55] +synonym: "SMP-I" RELATED [EC:3.1.3.55] +xref: EC:3.1.3.55 +xref: MetaCyc:CALDESMON-PHOSPHATASE-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047766 +name: carbamoyl-serine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate." [EC:4.3.1.13, RHEA:15445] +synonym: "carbamoylserine deaminase activity" EXACT [EC:4.3.1.13] +synonym: "O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming)" EXACT [EC:4.3.1.13] +synonym: "O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.13] +synonym: "O-carbamoyl-L-serine deaminase activity" EXACT [EC:4.3.1.13] +xref: EC:4.3.1.13 +xref: KEGG_REACTION:R00213 +xref: MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN +xref: RHEA:15445 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0047768 +name: carboxy-cis,cis-muconate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate." [EC:5.5.1.5, RHEA:14977] +synonym: "3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.5] +synonym: "3-carboxy-cis,cis-muconate lactonizing enzyme activity" EXACT [EC:5.5.1.5] +synonym: "3-carboxymuconate cyclase activity" EXACT [EC:5.5.1.5] +xref: EC:5.5.1.5 +xref: KEGG_REACTION:R03308 +xref: MetaCyc:CARBOXY-CISCIS-MUCONATE-CYCLASE-RXN +xref: RHEA:14977 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0047769 +name: arogenate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2." [EC:4.2.1.91, MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN] +synonym: "carboxycyclohexadienyl dehydratase activity" EXACT [] +synonym: "L-arogenate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.91] +synonym: "L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)" EXACT [EC:4.2.1.91] +xref: EC:4.2.1.91 +xref: MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN +xref: RHEA:12536 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047770 +name: carboxylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor." [EC:1.2.99.6, MetaCyc:CARBOXYLATE-REDUCTASE-RXN] +synonym: "aldehyde:(acceptor) oxidoreductase activity" EXACT [EC:1.2.99.6] +synonym: "aldehyde:acceptor oxidoreductase activity" EXACT [EC:1.2.99.6] +synonym: "carboxylic acid reductase activity" EXACT [EC:1.2.99.6] +xref: EC:1.2.99.6 +xref: MetaCyc:CARBOXYLATE-REDUCTASE-RXN +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0047771 +name: carboxymethylhydantoinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+)." [EC:3.5.2.4, RHEA:12028] +synonym: "hydantoin hydrolase activity" EXACT [EC:3.5.2.4] +synonym: "L-5-carboxymethylhydantoin amidohydrolase activity" EXACT [EC:3.5.2.4] +xref: EC:3.5.2.4 +xref: KEGG_REACTION:R02284 +xref: MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN +xref: RHEA:12028 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0047772 +name: carboxymethyloxysuccinate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate." [EC:4.2.99.12, RHEA:12336] +synonym: "carboxymethyloxysuccinate glycolate-lyase (fumarate-forming)" EXACT [EC:4.2.99.12] +synonym: "carboxymethyloxysuccinate glycolate-lyase activity" EXACT [EC:4.2.99.12] +xref: EC:4.2.99.12 +xref: KEGG_REACTION:R01336 +xref: MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN +xref: RHEA:12336 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0047773 +name: carnitinamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+)." [EC:3.5.1.73, RHEA:17537] +synonym: "carnitine amidase activity" EXACT [EC:3.5.1.73] +synonym: "L-carnitinamidase activity" EXACT [EC:3.5.1.73] +synonym: "L-carnitinamide amidohydrolase activity" EXACT [EC:3.5.1.73] +synonym: "L-carnitine amidase activity" EXACT [EC:3.5.1.73] +xref: EC:3.5.1.73 +xref: KEGG_REACTION:R01922 +xref: MetaCyc:CARNITINAMIDASE-RXN +xref: RHEA:17537 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047774 +name: cis-2-enoyl-CoA reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH." [EC:1.3.1.37, MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN] +synonym: "acyl-CoA:NADP+ cis-2-oxidoreductase activity" EXACT [EC:1.3.1.37] +synonym: "cis-2-enoyl-coenzyme A reductase activity" EXACT [EC:1.3.1.37] +synonym: "NADPH-dependent cis-enoyl-CoA reductase activity" EXACT [EC:1.3.1.37] +synonym: "reductase, cis-2-enoyl coenzyme A" EXACT [EC:1.3.1.37] +xref: EC:1.3.1.37 +xref: MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047775 +name: citramalate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA." [EC:2.8.3.11, MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN] +synonym: "acetyl-CoA:citramalate CoA-transferase activity" EXACT [EC:2.8.3.11] +xref: EC:2.8.3.11 +xref: MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN +xref: RHEA:17621 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0047776 +name: citramalate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-citramalate = acetate + pyruvate." [EC:4.1.3.22, RHEA:15545] +synonym: "(+)-citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] +synonym: "(3S)-citramalate pyruvate-lyase (acetate-forming)" EXACT [EC:4.1.3.22] +synonym: "(3S)-citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] +synonym: "(S)-citramalate lyase activity" EXACT [EC:4.1.3.22] +synonym: "citramalate pyruvate lyase activity" EXACT [EC:4.1.3.22] +synonym: "citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] +synonym: "citramalate synthetase activity" EXACT [EC:4.1.3.22] +synonym: "citramalic synthase activity" EXACT [EC:4.1.3.22] +synonym: "citramalic-condensing enzyme" RELATED [EC:4.1.3.22] +xref: EC:4.1.3.22 +xref: KEGG_REACTION:R00325 +xref: MetaCyc:CITRAMALATE-LYASE-RXN +xref: RHEA:15545 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047777 +name: (S)-citramalyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate." [EC:4.1.3.25, RHEA:22612] +synonym: "(+)-CMA-CoA lyase activity" EXACT [EC:4.1.3.25] +synonym: "(3S)-citramalyl-CoA lyase activity" EXACT [EC:4.1.3.25] +synonym: "(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.25] +synonym: "(3S)-citramalyl-CoA pyruvate-lyase activity" EXACT [EC:4.1.3.25] +synonym: "citramalyl coenzyme A lyase activity" EXACT [EC:4.1.3.25] +synonym: "citramalyl-CoA lyase activity" BROAD [] +xref: EC:4.1.3.25 +xref: KEGG_REACTION:R00237 +xref: MetaCyc:CITRAMALYL-COA-LYASE-RXN +xref: RHEA:22612 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0047778 +name: [citrate-(pro-3S)-lyase] thiolesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate." [EC:3.1.2.16, MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN] +synonym: "[citrate-(pro-3S)-lyase] thioesterase activity" EXACT [EC:3.1.2.16] +synonym: "citrate (pro-3S)-lyase thiolesterase activity" EXACT [] +synonym: "citrate lyase deacetylase activity" EXACT [EC:3.1.2.16] +synonym: "citrate-(pro-3S)-lyase thioesterase activity" EXACT [EC:3.1.2.16] +synonym: "citrate-(pro-3S)-lyase thiolesterase activity" EXACT [EC:3.1.2.16] +synonym: "citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity" EXACT [EC:3.1.2.16] +xref: EC:3.1.2.16 +xref: MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0047779 +name: citrate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate." [EC:6.2.1.18, RHEA:21472] +synonym: "citrate thiokinase activity" EXACT [EC:6.2.1.18] +synonym: "citrate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.18] +synonym: "citrate:CoA ligase activity" EXACT [EC:6.2.1.18] +synonym: "citryl-CoA synthetase activity" EXACT [EC:6.2.1.18] +xref: EC:6.2.1.18 +xref: KEGG_REACTION:R01322 +xref: MetaCyc:CITRATE--COA-LIGASE-RXN +xref: RHEA:21472 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047780 +name: citrate dehydratase activity +namespace: molecular_function +alt_id: GO:0052632 +def: "Catalysis of the reaction: citrate = cis-aconitate + H2O." [EC:4.2.1.3] +comment: This term is also a sub-reaction of 'aconitate hydratase activity ; GO:0003994 (EC:4.2.1.3)'. +synonym: "aconitate hydratase activity" BROAD [EC:4.2.1.3] +synonym: "citrate hydro-lyase (cis-aconitate-forming)" EXACT [EC:4.2.1.3] +synonym: "citrate hydro-lyase (cis-aconitate-forming) activity" EXACT [] +synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.3] +xref: EC:4.2.1.3 +xref: KEGG_REACTION:R01325 +xref: MetaCyc:ACONITATEDEHYDR-RXN +xref: MetaCyc:CITRATE-DEHYDRATASE-RXN +xref: RHEA:10228 +is_a: GO:0016836 ! hydro-lyase activity +relationship: has_part GO:0003994 ! aconitate hydratase activity + +[Term] +id: GO:0047781 +name: citrullinase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine." [EC:3.5.1.20, MetaCyc:CITRULLINASE-RXN] +synonym: "citrulline hydrolase activity" EXACT [EC:3.5.1.20] +synonym: "citrulline ureidase activity" EXACT [EC:3.5.1.20] +synonym: "L-citrulline 5-N-carbamoyldihydrolase activity" EXACT [EC:3.5.1.20] +synonym: "L-citrulline N5-carbamoyldihydrolase activity" EXACT [EC:3.5.1.20] +xref: EC:3.5.1.20 +xref: MetaCyc:CITRULLINASE-RXN +xref: RHEA:11940 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047782 +name: coniferin beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol." [EC:3.2.1.126, MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN] +synonym: "coniferin b-glucosidase activity" EXACT [] +synonym: "coniferin beta-D-glucosidase activity" EXACT [EC:3.2.1.126] +synonym: "coniferin-hydrolyzing beta-glucosidase activity" EXACT [EC:3.2.1.126] +xref: EC:3.2.1.126 +xref: MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN +xref: RHEA:12252 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0047783 +name: corticosterone 18-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.5, MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN] +synonym: "corticosterone 18-hydroxylase activity" EXACT [] +synonym: "corticosterone methyl oxidase activity" RELATED [EC:1.14.15.5] +synonym: "corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)" EXACT [EC:1.14.15.5] +xref: EC:1.14.15.5 +xref: MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047784 +name: cortisol O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate." [EC:2.3.1.27, RHEA:17073] +synonym: "acetyl-CoA:cortisol O-acetyltransferase activity" EXACT [EC:2.3.1.27] +synonym: "corticosteroid acetyltransferase activity" EXACT [EC:2.3.1.27] +synonym: "corticosteroid-21-O-acetyltransferase activity" EXACT [EC:2.3.1.27] +synonym: "cortisol acetyltransferase activity" EXACT [EC:2.3.1.27] +xref: EC:2.3.1.27 +xref: KEGG_REACTION:R02837 +xref: MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN +xref: RHEA:17073 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0047785 +name: cortisol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+)." [EC:2.8.2.18, RHEA:11884] +synonym: "3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity" EXACT [EC:2.8.2.18] +synonym: "cortisol sulphotransferase activity" EXACT [] +synonym: "glucocorticoid sulfotransferase activity" EXACT [EC:2.8.2.18] +synonym: "glucocorticosteroid sulfotransferase activity" BROAD [EC:2.8.2.18] +xref: EC:2.8.2.18 +xref: KEGG_REACTION:R02839 +xref: MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN +xref: RHEA:11884 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047786 +name: cortisone alpha-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH." [RHEA:17981] +synonym: "4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity" RELATED [] +synonym: "cortisone a-reductase activity" EXACT [] +synonym: "cortisone delta4-5alpha-reductase activity" RELATED [] +synonym: "delta4-3-ketosteroid reductase (5alpha)" EXACT [EC:1.3.1.4] +synonym: "delta4-3-oxosteroid-5alpha-reductase" RELATED [] +synonym: "delta4-5alpha-reductase activity" RELATED [] +synonym: "microsomal steroid reductase (5alpha)" EXACT [EC:1.3.1.4] +synonym: "NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity" RELATED [] +xref: KEGG_REACTION:R02892 +xref: MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN +xref: RHEA:17981 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047787 +name: delta4-3-oxosteroid 5beta-reductase activity +namespace: molecular_function +alt_id: GO:0047752 +def: "Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+." [EC:1.3.1.3, MetaCyc:CORTISONE-BETA-REDUCTASE-RXN] +synonym: "3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.23] +synonym: "3-oxo-Delta(4)-steroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "3-oxo-delta4-steroid 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.23] +synonym: "5-beta-reductase activity" BROAD [EC:1.3.1.23] +synonym: "5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity" EXACT [EC:1.3.1.23] +synonym: "5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "androstenedione 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "androstenedione 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "cholestenone 5-beta-reductase activity" EXACT [] +synonym: "cholestenone 5b-reductase activity" EXACT [] +synonym: "cholestenone 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "cortisone 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "cortisone 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "cortisone b-reductase activity" EXACT [] +synonym: "cortisone beta-reductase activity" EXACT [] +synonym: "cortisone delta(4)-5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "cortisone delta4-5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "delta(4)-3-ketosteroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "delta(4)-5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "delta(4)-hydrogenase activity" EXACT [EC:1.3.1.23] +synonym: "delta4-3-ketosteroid 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "delta4-3-oxosteroid 5-beta-reductase activity" EXACT [] +synonym: "delta4-5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "delta4-hydrogenase activity" EXACT [EC:1.3.1.23] +synonym: "steroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "steroid 5beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "testosterone 5-beta-reductase activity" EXACT [EC:1.3.1.23] +synonym: "testosterone 5beta-reductase activity" EXACT [EC:1.3.1.23] +xref: EC:1.3.1.3 +xref: MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN +xref: MetaCyc:CORTISONE-BETA-REDUCTASE-RXN +is_a: GO:0035671 ! enone reductase activity + +[Term] +id: GO:0047788 +name: 2-coumarate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH." [EC:1.3.1.11, RHEA:21444] +synonym: "3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.11] +synonym: "coumarate reductase activity" EXACT [] +synonym: "melilotate dehydrogenase activity" EXACT [EC:1.3.1.11] +xref: EC:1.3.1.11 +xref: KEGG_REACTION:R03709 +xref: MetaCyc:COUMARATE-REDUCTASE-RXN +xref: RHEA:21444 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047789 +name: creatininase activity +namespace: molecular_function +def: "Catalysis of the reaction: creatinine + H(2)O = creatine." [EC:3.5.2.10, RHEA:14533] +synonym: "creatinine amidohydrolase activity" EXACT [EC:3.5.2.10] +synonym: "creatinine hydrolase" BROAD [EC:3.5.2.10] +xref: EC:3.5.2.10 +xref: KEGG_REACTION:R01884 +xref: MetaCyc:CREATININASE-RXN +xref: RHEA:14533 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0047790 +name: creatinine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3." [EC:3.5.4.21, MetaCyc:CREATININE-DEAMINASE-RXN] +synonym: "creatinine desiminase activity" EXACT [EC:3.5.4.21] +synonym: "creatinine hydrolase" BROAD [EC:3.5.4.21] +synonym: "creatinine iminohydrolase activity" EXACT [EC:3.5.4.21] +xref: EC:3.5.4.21 +xref: MetaCyc:CREATININE-DEAMINASE-RXN +xref: RHEA:12681 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047791 +name: cucurbitacin delta23-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+." [EC:1.3.1.5, MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN] +synonym: "23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity" EXACT [EC:1.3.1.5] +synonym: "cucurbitacin D23-reductase activity" EXACT [] +synonym: "cucurbitacin delta(23) reductase activity" EXACT [] +synonym: "NAD(P)H: cucurbitacin B delta23-oxidoreductase activity" EXACT [EC:1.3.1.5] +xref: EC:1.3.1.5 +xref: MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047792 +name: cyanohydrin beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside." [EC:2.4.1.85, MetaCyc:CYANOHYDRIN-BETA-GLUCOSYLTRANSFERASE-RXN] +synonym: "cyanohydrin b-glucosyltransferase activity" EXACT [] +synonym: "UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "UGT85B1 activity" NARROW [EC:2.4.1.85] +synonym: "uridine diphosphoglucose-cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.85] +synonym: "uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.85] +xref: EC:2.4.1.85 +xref: RHEA:12853 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047793 +name: cycloeucalenol cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: cycloeucalenol = obtusifoliol." [EC:5.5.1.9, RHEA:22800] +synonym: "cycloeucalenol lyase (cyclopropane-decyclizing)" EXACT [EC:5.5.1.9] +synonym: "cycloeucalenol--obtusifoliol isomerase activity" EXACT [EC:5.5.1.9] +synonym: "cycloeucalenol-obtusifoliol isomerase activity" EXACT [] +xref: EC:5.5.1.9 +xref: KEGG_REACTION:R03775 +xref: MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN +xref: RHEA:22800 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0047794 +name: cyclohexadienyl dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2." [EC:1.3.1.43, MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN] +synonym: "arogenate dehydrogenase activity" EXACT [EC:1.3.1.43] +synonym: "arogenic dehydrogenase activity" EXACT [EC:1.3.1.43] +synonym: "L-arogenate:NAD(+) oxidoreductase activity" EXACT [EC:1.3.1.43] +synonym: "L-arogenate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.43] +synonym: "L-arogenate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.43] +synonym: "pretyrosine dehydrogenase activity" EXACT [EC:1.3.1.43] +xref: EC:1.3.1.43 +xref: MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN +xref: RHEA:12256 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047795 +name: cyclohexane-1,2-diol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH." [EC:1.1.1.174, MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN] +synonym: "trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.174] +xref: EC:1.1.1.174 +xref: MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN +xref: RHEA:18141 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047796 +name: cyclohexane-1,3-dione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+)." [EC:3.7.1.10, RHEA:16473] +synonym: "1,3-cyclohexanedione hydrolase activity" EXACT [EC:3.7.1.10] +synonym: "cyclohexane-1,3-dione acylhydrolase (decyclizing)" EXACT [EC:3.7.1.10] +xref: EC:3.7.1.10 +xref: KEGG_REACTION:R03211 +xref: MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN +xref: RHEA:16473 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0047797 +name: cyclohexanone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone." [EC:1.3.99.14, RHEA:21780] +synonym: "cyclohexanone:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.3.99.14] +synonym: "cyclohexanone:acceptor 2-oxidoreductase activity" EXACT [EC:1.3.99.14] +xref: EC:1.3.99.14 +xref: KEGG_REACTION:R02234 +xref: MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN +xref: RHEA:21780 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0047798 +name: cyclomaltodextrinase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin." [EC:3.2.1.54, MetaCyc:CYCLOMALTODEXTRINASE-RXN] +synonym: "cyclodextrinase activity" EXACT [EC:3.2.1.54] +synonym: "cycloheptaglucanase activity" EXACT [EC:3.2.1.54] +synonym: "cyclohexaglucanase activity" EXACT [EC:3.2.1.54] +synonym: "cyclomaltodextrin dextrin-hydrolase (decyclizing)" EXACT [EC:3.2.1.54] +xref: EC:3.2.1.54 +xref: MetaCyc:CYCLOMALTODEXTRINASE-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047799 +name: cyclopentanone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+)." [EC:1.14.13.16, RHEA:15737] +synonym: "cyclopentanone 1,2-monooxygenase activity" EXACT [EC:1.14.13.16] +synonym: "cyclopentanone oxygenase activity" EXACT [EC:1.14.13.16] +synonym: "cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)" EXACT [EC:1.14.13.16] +xref: EC:1.14.13.16 +xref: KEGG_REACTION:R02554 +xref: MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN +xref: RHEA:15737 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047800 +name: cysteamine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine." [EC:1.13.11.19, RHEA:14409] +synonym: "2-aminoethanethiol:oxygen oxidoreductase activity" EXACT [EC:1.13.11.19] +synonym: "cysteamine oxygenase activity" EXACT [EC:1.13.11.19] +synonym: "cysteamine:oxygen oxidoreductase activity" EXACT [EC:1.13.11.19] +synonym: "persulfurase activity" RELATED [EC:1.13.11.19] +xref: EC:1.13.11.19 +xref: KEGG_REACTION:R02467 +xref: MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN +xref: Reactome:R-HSA-6814153 "ADO oxidises 2AET to HTAU" +xref: RHEA:14409 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047801 +name: L-cysteine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate." [EC:2.6.1.3, MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN] +synonym: "CGT" RELATED [EC:2.6.1.3] +synonym: "cysteine aminotransferase activity" BROAD [] +synonym: "cysteine transaminase activity" BROAD [EC:2.6.1.3] +synonym: "L-cysteine aminotransferase activity" BROAD [EC:2.6.1.3] +xref: EC:2.6.1.3 +xref: MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-9012597 "GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu" +xref: RHEA:17441 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047802 +name: cysteine-conjugate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate." [EC:2.6.1.75, RHEA:13485] +synonym: "cysteine conjugate aminotransferase activity" EXACT [EC:2.6.1.75] +synonym: "cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)" EXACT [EC:2.6.1.75] +synonym: "S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.75] +xref: EC:2.6.1.75 +xref: KEGG_REACTION:R04338 +xref: MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN +xref: RHEA:13485 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047803 +name: cysteine lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide." [EC:4.4.1.10, MetaCyc:CYSTEINE-LYASE-RXN] +synonym: "cysteine (sulfite) lyase activity" EXACT [EC:4.4.1.10] +synonym: "L-cysteine hydrogen-sulfide-lyase (adding sulfite)" EXACT [EC:4.4.1.10] +synonym: "L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)" EXACT [EC:4.4.1.10] +xref: EC:4.4.1.10 +xref: MetaCyc:CYSTEINE-LYASE-RXN +xref: RHEA:20916 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0047804 +name: cysteine-S-conjugate beta-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate." [EC:4.4.1.13, MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN] +synonym: "cysteine conjugate beta-lyase activity" EXACT [EC:4.4.1.13] +synonym: "cysteine-S-conjugate b-lyase activity" EXACT [] +synonym: "glutamine transaminase K/cysteine conjugate beta-lyase activity" EXACT [EC:4.4.1.13] +synonym: "L-cysteine-S-conjugate thiol-lyase (deaminating) activity" EXACT [EC:4.4.1.13] +synonym: "L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.13] +xref: EC:4.4.1.13 +xref: MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0047805 +name: cytidylate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+)." [EC:4.6.1.6, RHEA:14737] +synonym: "3',5'-cyclic-CMP synthase activity" EXACT [EC:4.6.1.6] +synonym: "3'5'-cyclic-CMP synthase activity" EXACT [EC:4.6.1.6] +synonym: "CTP diphosphate-lyase (cyclizing)" EXACT [EC:4.6.1.6] +synonym: "CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)" EXACT [EC:4.6.1.6] +synonym: "cytidyl cyclase activity" EXACT [EC:4.6.1.6] +synonym: "cytidylyl cyclase activity" EXACT [EC:4.6.1.6] +xref: EC:4.6.1.6 +xref: KEGG_REACTION:R00574 +xref: MetaCyc:CYTIDYLATE-CYCLASE-RXN +xref: RHEA:14737 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016849 ! phosphorus-oxygen lyase activity +relationship: part_of GO:0009190 ! cyclic nucleotide biosynthetic process + +[Term] +id: GO:0047806 +name: cytochrome-c3 hydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3." [EC:1.12.2.1, MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN] +synonym: "cytochrome c3 reductase activity" EXACT [EC:1.12.2.1] +synonym: "cytochrome hydrogenase activity" BROAD [EC:1.12.2.1] +synonym: "H(2):ferricytochrome c3 oxidoreductase activity" EXACT [EC:1.12.2.1] +synonym: "H2:ferricytochrome c3 oxidoreductase activity" EXACT [EC:1.12.2.1] +synonym: "hydrogen:ferricytochrome-c3 oxidoreductase activity" EXACT [EC:1.12.2.1] +xref: EC:1.12.2.1 +xref: MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN +xref: UM-BBD_enzymeID:e0481 +is_a: GO:0016697 ! oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor + +[Term] +id: GO:0047807 +name: cytokinin 7-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event." [EC:2.4.1.118, MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN] +synonym: "cytokinin 7-b-glucosyltransferase activity" EXACT [] +synonym: "cytokinin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] +synonym: "UDP-glucose-zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] +synonym: "UDP-glucose:zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] +synonym: "UDPglucose:zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] +synonym: "uridine diphosphoglucose-zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] +xref: EC:2.4.1.118 +xref: KEGG_REACTION:R04071 +xref: MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:23272 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047808 +name: D(-)-tartrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate." [EC:4.2.1.81, RHEA:18289] +synonym: "(S,S)-tartrate hydro-lyase (oxaloacetate-forming)" EXACT [EC:4.2.1.81] +synonym: "(S,S)-tartrate hydro-lyase activity" EXACT [EC:4.2.1.81] +synonym: "D-tartrate dehydratase activity" EXACT [EC:4.2.1.81] +xref: EC:4.2.1.81 +xref: KEGG_REACTION:R00340 +xref: MetaCyc:D--TARTRATE-DEHYDRATASE-RXN +xref: RHEA:18289 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047809 +name: D-2-hydroxy-acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate." [EC:1.1.99.6, RHEA:15089] +synonym: "(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.6] +synonym: "2-hydroxy acid dehydrogenase activity" EXACT [EC:1.1.99.6] +xref: EC:1.1.99.6 +xref: KEGG_REACTION:R00297 +xref: MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN +xref: RHEA:15089 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047810 +name: D-alanine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate." [EC:2.6.1.21, MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN] +synonym: "D-alanine aminotransferase activity" EXACT [] +synonym: "D-alanine transaminase activity" BROAD [EC:2.6.1.21] +synonym: "D-alanine-D-glutamate transaminase activity" EXACT [EC:2.6.1.21] +synonym: "D-amino acid aminotransferase activity" BROAD [EC:2.6.1.21] +synonym: "D-amino acid transaminase activity" BROAD [EC:2.6.1.21] +synonym: "D-amino-acid transaminase activity" BROAD [EC:2.6.1.21] +synonym: "D-aspartate aminotransferase activity" RELATED [EC:2.6.1.21] +synonym: "D-aspartate transaminase activity" RELATED [EC:2.6.1.21] +synonym: "D-aspartic aminotransferase activity" RELATED [EC:2.6.1.21] +xref: EC:2.6.1.21 +xref: MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN +xref: RHEA:15869 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047811 +name: D-alanine gamma-glutamyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+)." [EC:2.3.2.14, RHEA:23556] +synonym: "D-alanine g-glutamyltransferase activity" EXACT [] +synonym: "L-glutamine:D-alanine gamma-glutamyltransferase activity" EXACT [EC:2.3.2.14] +xref: EC:2.3.2.14 +xref: KEGG_REACTION:R01149 +xref: MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN +xref: RHEA:23556 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0047812 +name: D-amino-acid N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid." [EC:2.3.1.36, MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN] +synonym: "acetyl-CoA:D-amino-acid N-acetyltransferase activity" EXACT [EC:2.3.1.36] +synonym: "D-amino acid acetyltransferase activity" EXACT [EC:2.3.1.36] +synonym: "D-amino acid-alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.36] +xref: EC:2.3.1.36 +xref: MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN +xref: RHEA:20704 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047813 +name: D-arabinitol 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH." [EC:1.1.1.11, MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN] +xref: EC:1.1.1.11 +xref: MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN +xref: RHEA:17921 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047814 +name: D-arabinokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP." [EC:2.7.1.54, RHEA:24588] +synonym: "ATP:D-arabinose 5-phosphotransferase activity" EXACT [EC:2.7.1.54] +synonym: "D-arabinokinase (phosphorylating)" EXACT [EC:2.7.1.54] +xref: EC:2.7.1.54 +xref: KEGG_REACTION:R01573 +xref: MetaCyc:D-ARABINOKINASE-RXN +xref: RHEA:24588 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047815 +name: D-arabinonolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+)." [EC:3.1.1.30, RHEA:23108] +synonym: "D-arabinono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.30] +xref: EC:3.1.1.30 +xref: KEGG_REACTION:R02714 +xref: MetaCyc:D-ARABINONOLACTONASE-RXN +xref: RHEA:23108 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047816 +name: D-arabinose 1-dehydrogenase (NAD) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH." [EC:1.1.1.116, MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN] +synonym: "arabinose(fucose)dehydrogenase activity" EXACT [EC:1.1.1.116] +synonym: "D-arabinose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.116] +synonym: "NAD-pentose-dehydrogenase activity" EXACT [EC:1.1.1.116] +xref: EC:1.1.1.116 +xref: MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN +xref: RHEA:20457 +is_a: GO:0045290 ! D-arabinose 1-dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0047817 +name: D-arginase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea." [EC:3.5.3.10, RHEA:12901] +synonym: "D-arginine amidinohydrolase activity" EXACT [EC:3.5.3.10] +xref: EC:3.5.3.10 +xref: KEGG_REACTION:R02458 +xref: MetaCyc:D-ARGINASE-RXN +xref: RHEA:12901 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047818 +name: D-fuconate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O." [EC:4.2.1.67, RHEA:12949] +synonym: "D-fuconate hydratase activity" EXACT [] +synonym: "D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)" EXACT [EC:4.2.1.67] +synonym: "D-fuconate hydro-lyase activity" EXACT [EC:4.2.1.67] +xref: EC:4.2.1.67 +xref: KEGG_REACTION:R03671 +xref: MetaCyc:D-FUCONATE-HYDRATASE-RXN +xref: RHEA:12949 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047819 +name: D-glutamate(D-aspartate) oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2." [EC:1.4.3.15, MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN] +comment: For the individual reactions, see instead 'D-glutamate oxidase activity ;GO:0047821' and 'D-aspartate oxidase activity ; GO:0008445'. +synonym: "D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.15] +synonym: "D-glutamic-aspartic oxidase activity" EXACT [EC:1.4.3.15] +synonym: "D-monoaminodicarboxylic acid oxidase activity" EXACT [EC:1.4.3.15] +xref: EC:1.4.3.15 +xref: MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN +is_a: GO:0003884 ! D-amino-acid oxidase activity + +[Term] +id: GO:0047820 +name: D-glutamate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O." [EC:4.2.1.48, RHEA:22360] +synonym: "D-glutamate hydro-lyase (cyclizing)" EXACT [EC:4.2.1.48] +synonym: "D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)" EXACT [EC:4.2.1.48] +xref: EC:4.2.1.48 +xref: KEGG_REACTION:R01583 +xref: MetaCyc:D-GLUTAMATE-CYCLASE-RXN +xref: RHEA:22360 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047821 +name: D-glutamate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2." [EC:1.4.3.7, MetaCyc:D-GLUTAMATE-OXIDASE-RXN] +synonym: "D-glutamate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.7] +synonym: "D-glutamic acid oxidase activity" EXACT [EC:1.4.3.7] +synonym: "D-glutamic oxidase activity" EXACT [EC:1.4.3.7] +xref: EC:1.4.3.7 +xref: KEGG_REACTION:R00279 +xref: MetaCyc:D-GLUTAMATE-OXIDASE-RXN +xref: RHEA:10028 +is_a: GO:0003884 ! D-amino-acid oxidase activity + +[Term] +id: GO:0047822 +name: hypotaurine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine." [EC:1.8.1.3, RHEA:17385] +synonym: "hypotaurine:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.3] +xref: EC:1.8.1.3 +xref: KEGG_REACTION:R01681 +xref: MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-1655453 "HTAUDH oxidises HTAU to TAU" +xref: RHEA:17385 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0047823 +name: D-glutamyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide." [EC:2.3.2.1, MetaCyc:D-GLUTAMYLTRANSFERASE-RXN] +synonym: "D-gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.1] +synonym: "D-glutamyl transpeptidase activity" EXACT [EC:2.3.2.1] +synonym: "glutamine:D-glutamyl-peptide 5-glutamyltransferase activity" EXACT [EC:2.3.2.1] +xref: EC:2.3.2.1 +xref: MetaCyc:D-GLUTAMYLTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0047824 +name: D-iditol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH." [EC:1.1.1.15, MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN] +xref: EC:1.1.1.15 +xref: MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN +xref: RHEA:12725 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +is_a: GO:0031320 ! hexitol dehydrogenase activity + +[Term] +id: GO:0047825 +name: D-lactate-2-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate." [EC:3.1.6.17, RHEA:20337] +synonym: "(S)-2-O-sulfolactate 2-sulfohydrolase activity" EXACT [EC:3.1.6.17] +synonym: "D-lactate-2-sulphatase activity" EXACT [] +xref: EC:3.1.6.17 +xref: KEGG_REACTION:R01448 +xref: MetaCyc:D-LACTATE-2-SULFATASE-RXN +xref: RHEA:20337 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0047826 +name: D-lysine 5,6-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate." [EC:5.4.3.4, RHEA:18241] +synonym: "adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity" EXACT [EC:5.4.3.4] +synonym: "D-2,6-diaminohexanoate 5,6-aminomutase activity" EXACT [EC:5.4.3.4] +synonym: "D-alpha-lysine mutase activity" EXACT [EC:5.4.3.4] +xref: EC:5.4.3.4 +xref: KEGG_REACTION:R02852 +xref: MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN +xref: RHEA:18241 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0047827 +name: D-lysopine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate." [EC:1.5.1.16, RHEA:17625] +synonym: "2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.16] +synonym: "D(+)-lysopine dehydrogenase activity" EXACT [EC:1.5.1.16] +synonym: "D-lysopine synthase activity" EXACT [EC:1.5.1.16] +synonym: "lysopine dehydrogenase activity" EXACT [EC:1.5.1.16] +synonym: "N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.16] +xref: EC:1.5.1.16 +xref: KEGG_REACTION:R00452 +xref: MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN +xref: RHEA:17625 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047828 +name: D-lyxose ketol-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-lyxose = D-xylulose." [EC:5.3.1.15, RHEA:14201] +synonym: "D-lyxose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.15] +synonym: "D-lyxose isomerase activity" EXACT [EC:5.3.1.15] +xref: EC:5.3.1.15 +xref: KEGG_REACTION:R01898 +xref: MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN +xref: RHEA:14201 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0047829 +name: D-nopaline dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH." [EC:1.5.1.19, MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN] +synonym: "2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.19] +synonym: "D-nopaline synthase activity" EXACT [EC:1.5.1.19] +synonym: "N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.19] +synonym: "nopaline dehydrogenase activity" EXACT [EC:1.5.1.19] +synonym: "nopaline synthase activity" EXACT [EC:1.5.1.19] +synonym: "NOS activity" EXACT [EC:1.5.1.19] +xref: EC:1.5.1.19 +xref: MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN +xref: RHEA:19637 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047830 +name: D-octopine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH." [EC:1.5.1.11, MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN] +synonym: "2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.11] +synonym: "D-octopine synthase activity" EXACT [EC:1.5.1.11] +synonym: "N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.11] +synonym: "octopine dehydrogenase activity" EXACT [EC:1.5.1.11] +synonym: "octopine:NAD oxidoreductase activity" EXACT [EC:1.5.1.11] +synonym: "ODH activity" EXACT [EC:1.5.1.11] +xref: EC:1.5.1.11 +xref: MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN +xref: RHEA:16285 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047831 +name: D-ornithine 4,5-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate." [EC:5.4.3.5, RHEA:14893] +synonym: "D-alpha-ornithine 5,4-aminomutase activity" EXACT [EC:5.4.3.5] +synonym: "D-ornithine aminomutase activity" EXACT [EC:5.4.3.5] +xref: EC:5.4.3.5 +xref: KEGG_REACTION:R02461 +xref: MetaCyc:ORNMUTST-RXN +xref: RHEA:14893 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0047832 +name: D-pinitol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH." [EC:1.1.1.142, RHEA:20437] +synonym: "1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.142] +synonym: "5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.142] +xref: EC:1.1.1.142 +xref: KEGG_REACTION:R03498 +xref: MetaCyc:D-PINITOL-DEHYDROGENASE-RXN +xref: RHEA:20437 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047833 +name: D-sorbitol dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor." [EC:1.1.99.21, MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN] +synonym: "D-sorbitol dehydrogenase activity" EXACT [] +synonym: "D-sorbitol:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.21] +synonym: "D-sorbitol:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.21] +xref: EC:1.1.99.21 +xref: MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN +xref: RHEA:21320 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047834 +name: D-threo-aldose 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH." [EC:1.1.1.122, MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN] +synonym: "(2S,3R)-aldose dehydrogenase activity" EXACT [EC:1.1.1.122] +synonym: "D-threo-aldose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.122] +synonym: "dehydrogenase, L-fucose" EXACT [EC:1.1.1.122] +synonym: "L-fucose (D-arabinose) dehydrogenase activity" EXACT [EC:1.1.1.122] +synonym: "L-fucose dehydrogenase activity" EXACT [EC:1.1.1.122] +xref: EC:1.1.1.122 +xref: MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047835 +name: D-tryptophan N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+)." [EC:2.3.1.34, RHEA:10060] +synonym: "acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.34] +synonym: "acetyl-CoA:D-tryptophan N-acetyltransferase activity" EXACT [EC:2.3.1.34] +synonym: "D-tryptophan acetyltransferase activity" EXACT [EC:2.3.1.34] +xref: EC:2.3.1.34 +xref: KEGG_REACTION:R02481 +xref: MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN +xref: RHEA:10060 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047836 +name: D-tryptophan N-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+)." [EC:2.3.1.112, RHEA:23320] +synonym: "malonyl-CoA:D-tryptophan N-malonyltransferase activity" EXACT [EC:2.3.1.112] +xref: EC:2.3.1.112 +xref: KEGG_REACTION:R02482 +xref: MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN +xref: RHEA:23320 +is_a: GO:0050735 ! N-malonyltransferase activity + +[Term] +id: GO:0047837 +name: D-xylose 1-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH." [EC:1.1.1.179, RHEA:22000] +synonym: "D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.179] +synonym: "D-xylose-NADP dehydrogenase activity" EXACT [EC:1.1.1.179] +synonym: "D-xylose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.179] +synonym: "D-xylose:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.179] +xref: EC:1.1.1.179 +xref: KEGG_REACTION:R01430 +xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN +xref: RHEA:22000 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047838 +name: D-xylose 1-dehydrogenase (NAD) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH." [EC:1.1.1.175, MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN] +synonym: "(NAD)-linked D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] +synonym: "D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] +synonym: "D-xylose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.175] +synonym: "NAD-D-xylose" RELATED [EC:1.1.1.175] +synonym: "NAD-D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] +synonym: "NAD-linked D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] +xref: EC:1.1.1.175 +xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN +xref: RHEA:13861 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047839 +name: dATP(dGTP)-DNA purinetransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA." [EC:2.6.99.1, MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN] +synonym: "dATP(dGTP)--DNA purine transferase activity" EXACT [] +synonym: "dATP(dGTP):depurinated-DNA purine transferase activity" EXACT [EC:2.6.99.1] +xref: EC:2.6.99.1 +xref: MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN +is_a: GO:0016769 ! transferase activity, transferring nitrogenous groups + +[Term] +id: GO:0047840 +name: dCTP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate." [RHEA:22636] +synonym: "dCTP nucleotidohydrolase activity" EXACT [EC:3.6.1.12] +synonym: "dCTP pyrophosphatase activity" EXACT [] +synonym: "dCTPase activity" EXACT [EC:3.6.1.12] +synonym: "deoxy-CTPase activity" EXACT [EC:3.6.1.12] +synonym: "deoxycytidine triphosphatase activity" EXACT [EC:3.6.1.12] +synonym: "deoxycytidine-triphosphatase activity" EXACT [EC:3.6.1.12] +xref: EC:3.6.1.12 +xref: MetaCyc:DCTP-PYROPHOSPHATASE-RXN +xref: Reactome:R-HSA-6786257 "DCTPP1 hydrolyses 5idCTP" +xref: RHEA:22636 +is_a: GO:0047429 ! nucleoside-triphosphate diphosphatase activity + +[Term] +id: GO:0047841 +name: dehydrogluconokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+)." [EC:2.7.1.13, RHEA:10788] +synonym: "2-ketogluconate kinase activity" EXACT [EC:2.7.1.13] +synonym: "2-ketogluconokinase activity" EXACT [EC:2.7.1.13] +synonym: "ATP:2-dehydro-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.13] +synonym: "dehydogluconokinase activity" EXACT [] +synonym: "ketogluconokinase (phosphorylating)" EXACT [EC:2.7.1.13] +synonym: "ketogluconokinase activity" EXACT [EC:2.7.1.13] +xref: EC:2.7.1.13 +xref: KEGG_REACTION:R02658 +xref: MetaCyc:DEHYDOGLUCONOKINASE-RXN +xref: RHEA:10788 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047842 +name: dehydro-L-gulonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2)." [EC:4.1.1.34, RHEA:11084] +synonym: "3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)" EXACT [EC:4.1.1.34] +synonym: "3-dehydro-L-gulonate carboxy-lyase activity" EXACT [EC:4.1.1.34] +synonym: "3-keto-L-gulonate decarboxylase activity" EXACT [EC:4.1.1.34] +synonym: "keto-L-gulonate decarboxylase activity" EXACT [EC:4.1.1.34] +xref: EC:4.1.1.34 +xref: KEGG_REACTION:R01905 +xref: MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-5662473 "KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose" +xref: RHEA:11084 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047843 +name: dehydrogluconate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2)." [EC:1.1.99.4, RHEA:12368] +synonym: "2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.4] +synonym: "2-keto-D-gluconate dehydrogenase activity" EXACT [EC:1.1.99.4] +synonym: "2-oxogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] +synonym: "alpha-ketogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] +synonym: "ketogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] +xref: EC:1.1.99.4 +xref: KEGG_REACTION:R07153 +xref: MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN +xref: RHEA:12368 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047844 +name: deoxycytidine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3." [EC:3.5.4.14, MetaCyc:DEOXYCYTIDINE-DEAMINASE-RXN] +synonym: "deoxycytidine aminohydrolase activity" EXACT [EC:3.5.4.14] +xref: EC:3.5.4.14 +xref: MetaCyc:CYTIDEAM-RXN +xref: RHEA:13433 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047845 +name: deoxylimonate A-ring-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+)." [EC:3.1.1.46, RHEA:14997] +synonym: "deoxylimonate A-ring-lactonohydrolase activity" EXACT [EC:3.1.1.46] +xref: EC:3.1.1.46 +xref: KEGG_REACTION:R03803 +xref: MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN +xref: RHEA:14997 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047846 +name: deoxynucleotide 3'-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate." [EC:3.1.3.34, MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN] +synonym: "3'-deoxynucleotidase activity" EXACT [EC:3.1.3.34] +synonym: "3'-deoxyribonucleotidase activity" EXACT [EC:3.1.3.34] +synonym: "deoxyribonucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.3.34] +xref: EC:3.1.3.34 +xref: MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047847 +name: deoxyuridine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate." [EC:2.4.2.23, MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN] +synonym: "2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] +synonym: "deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] +synonym: "deoxyuridine:phosphate deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] +xref: EC:2.4.2.23 +xref: MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN +xref: RHEA:22824 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047848 +name: dephospho-[reductase kinase] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]." [EC:2.7.11.3, MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN] +synonym: "AMP-activated kinase activity" EXACT [EC:2.7.11.3] +synonym: "AMP-activated protein kinase kinase activity" EXACT [EC:2.7.11.3] +synonym: "ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity" EXACT [EC:2.7.11.3] +synonym: "dephospho-reductase kinase kinase activity" EXACT [EC:2.7.11.3] +synonym: "hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity" EXACT [EC:2.7.11.3] +synonym: "hydroxymethylglutaryl coenzyme A reductase kinase kinase activity" EXACT [EC:2.7.11.3] +synonym: "reductase kinase activity" BROAD [EC:2.7.11.3] +synonym: "reductase kinase kinase activity" EXACT [EC:2.7.11.3] +synonym: "STK30" RELATED [EC:2.7.11.3] +xref: EC:2.7.11.3 +xref: MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0047849 +name: dextransucrase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1)." [EC:2.4.1.5, MetaCyc:DEXTRANSUCRASE-RXN] +synonym: "CEP" RELATED [EC:2.4.1.5] +synonym: "SGE" RELATED [EC:2.4.1.5] +synonym: "sucrose 6-glucosyltransferase activity" EXACT [EC:2.4.1.5] +synonym: "sucrose-1,6-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.5] +synonym: "sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.5] +xref: EC:2.4.1.5 +xref: MetaCyc:DEXTRANSUCRASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0047850 +name: diaminopimelate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+)." [EC:1.4.1.16, RHEA:13561] +synonym: "meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.16] +synonym: "meso-alpha,epsilon-diaminopimelate dehydrogenase activity" EXACT [EC:1.4.1.16] +synonym: "meso-diaminopimelate D-dehydrogenase activity" EXACT [EC:1.4.1.16] +synonym: "meso-diaminopimelate dehydrogenase activity" EXACT [EC:1.4.1.16] +xref: EC:1.4.1.16 +xref: KEGG_REACTION:R02755 +xref: MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN +xref: RHEA:13561 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047851 +name: dicarboxylate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA." [EC:6.2.1.23, MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN] +synonym: "carboxylyl-CoA synthetase activity" EXACT [EC:6.2.1.23] +synonym: "omega-dicarboxylate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.23] +xref: EC:6.2.1.23 +xref: MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047852 +name: diferric-transferrin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH." [EC:1.16.1.2, MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN] +synonym: "diferric transferrin reductase activity" EXACT [EC:1.16.1.2] +synonym: "NADH diferric transferrin reductase activity" EXACT [EC:1.16.1.2] +synonym: "transferrin reductase activity" EXACT [EC:1.16.1.2] +synonym: "transferrin[Fe(II)]2:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.2] +xref: EC:1.16.1.2 +xref: MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0047853 +name: difructose-anhydride synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose." [EC:3.2.1.134, MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN] +synonym: "bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity" EXACT [EC:3.2.1.134] +synonym: "inulobiose hydrolase activity" EXACT [EC:3.2.1.134] +xref: EC:3.2.1.134 +xref: MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN +xref: RHEA:15041 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047854 +name: diguanidinobutanase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea." [EC:3.5.3.20, RHEA:13597] +synonym: "1,4-diguanidinobutane amidinohydrolase activity" EXACT [EC:3.5.3.20] +xref: EC:3.5.3.20 +xref: KEGG_REACTION:R01418 +xref: MetaCyc:DIGUANIDINOBUTANASE-RXN +xref: RHEA:13597 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047855 +name: dihydrobunolol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH." [EC:1.1.1.160, RHEA:15925] +synonym: "(+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.160] +synonym: "bunolol reductase activity" EXACT [EC:1.1.1.160] +xref: EC:1.1.1.160 +xref: KEGG_REACTION:R04623 +xref: MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN +xref: RHEA:15925 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047856 +name: dihydrocoumarin hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+)." [EC:3.1.1.35, RHEA:10360] +synonym: "dihydrocoumarin lactonohydrolase activity" EXACT [EC:3.1.1.35] +synonym: "dihydrocoumarin lipase activity" EXACT [] +xref: EC:3.1.1.35 +xref: KEGG_REACTION:R03692 +xref: MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN +xref: RHEA:10360 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047857 +name: dihydrouracil oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil." [EC:1.3.3.7, RHEA:12384] +synonym: "5,6-dihydrouracil:oxygen oxidoreductase activity" EXACT [EC:1.3.3.7] +xref: EC:1.3.3.7 +xref: KEGG_REACTION:R00975 +xref: MetaCyc:DIHYDROURACIL-OXIDASE-RXN +xref: RHEA:12384 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0047858 +name: dihydroxyfumarate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2)." [EC:4.1.1.54, RHEA:13845] +synonym: "dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming)" EXACT [EC:4.1.1.54] +synonym: "dihydroxyfumarate carboxy-lyase activity" EXACT [EC:4.1.1.54] +xref: EC:4.1.1.54 +xref: KEGG_REACTION:R03127 +xref: MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN +xref: RHEA:13845 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047859 +name: obsolete dihydroxyphenylalanine ammonia-lyase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine = trans-caffeate + NH3." [EC:4.3.1.11, MetaCyc:DIHYDROXYPHENYLALANINE-AMMONIA-LYASE-RXN] +comment: This term was made obsolete because the corresponding EC reaction (EC:4.3.1.11) has been deleted from the EC. +synonym: "3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming)" EXACT [EC:4.3.1.11] +synonym: "3,4-dihydroxy-L-phenylalanine ammonia-lyase activity" EXACT [EC:4.3.1.11] +synonym: "beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase activity" EXACT [EC:4.3.1.11] +synonym: "dihydroxyphenylalanine ammonia-lyase activity" EXACT [] +xref: EC:4.3.1.11 +is_obsolete: true + +[Term] +id: GO:0047860 +name: diiodophenylpyruvate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH." [EC:1.1.1.96, RHEA:20293] +synonym: "2-oxo acid reductase activity" EXACT [EC:1.1.1.96] +synonym: "3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.96] +synonym: "aromatic alpha-keto acid" RELATED [EC:1.1.1.96] +synonym: "KAR" RELATED [EC:1.1.1.96] +xref: EC:1.1.1.96 +xref: KEGG_REACTION:R03431 +xref: MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN +xref: RHEA:20293 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047861 +name: diiodotyrosine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate." [EC:2.6.1.24, RHEA:19781] +synonym: "3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.24] +synonym: "diiodotyrosine aminotransferase activity" EXACT [] +synonym: "halogenated tyrosine aminotransferase activity" EXACT [EC:2.6.1.24] +synonym: "halogenated tyrosine transaminase activity" EXACT [EC:2.6.1.24] +xref: EC:2.6.1.24 +xref: KEGG_REACTION:R03207 +xref: MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN +xref: RHEA:19781 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047862 +name: diisopropyl-fluorophosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride." [EC:3.1.8.2, RHEA:24100] +synonym: "DFPase activity" EXACT [EC:3.1.8.2] +synonym: "dialkylfluorophosphatase activity" EXACT [EC:3.1.8.2] +synonym: "diisopropyl phosphorofluoridate hydrolase activity" EXACT [EC:3.1.8.2] +synonym: "diisopropyl-fluorophosphate fluorohydrolase activity" EXACT [EC:3.1.8.2] +synonym: "diisopropylfluorophosphonate dehalogenase activity" EXACT [EC:3.1.8.2] +synonym: "diisopropylphosphofluoridase activity" EXACT [EC:3.1.8.2] +synonym: "isopropylphosphorofluoridase activity" EXACT [EC:3.1.8.2] +synonym: "OPA anhydrase activity" EXACT [EC:3.1.8.2] +synonym: "OPAA activity" EXACT [EC:3.1.8.2] +synonym: "organophosphate acid anhydrase activity" EXACT [EC:3.1.8.2] +synonym: "organophosphorus acid anhydrolase activity" EXACT [EC:3.1.8.2] +synonym: "somanase activity" EXACT [EC:3.1.8.2] +synonym: "tabunase activity" EXACT [EC:3.1.8.2] +xref: EC:3.1.8.2 +xref: KEGG_REACTION:R01533 +xref: MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN +xref: RHEA:24100 +is_a: GO:0016795 ! phosphoric triester hydrolase activity + +[Term] +id: GO:0047863 +name: dimethylallylcistransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate." [EC:2.5.1.28, RHEA:11328] +synonym: "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity" EXACT [EC:2.5.1.28] +synonym: "neryl-diphosphate synthase activity" EXACT [EC:2.5.1.28] +xref: EC:2.5.1.28 +xref: KEGG_REACTION:R01659 +xref: MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN +xref: RHEA:11328 +is_a: GO:0004659 ! prenyltransferase activity + +[Term] +id: GO:0047864 +name: dimethylaniline-N-oxide aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde." [EC:4.1.2.24, RHEA:19321] +synonym: "microsomal N-oxide dealkylase activity" EXACT [EC:4.1.2.24] +synonym: "microsomal oxidase II" RELATED [EC:4.1.2.24] +synonym: "N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)" EXACT [EC:4.1.2.24] +synonym: "N,N-dimethylaniline-N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.24] +xref: EC:4.1.2.24 +xref: KEGG_REACTION:R03345 +xref: MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN +xref: RHEA:19321 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047865 +name: dimethylglycine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein." [EC:1.5.8.4, RHEA:52856] +comment: Note that this was EC:1.5.99.2. +synonym: "N,N-dimethylglycine oxidase activity" EXACT [EC:1.5.8.4] +synonym: "N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.8.4] +synonym: "N,N-dimethylglycine:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.8.4] +xref: EC:1.5.8.4 +xref: KEGG_REACTION:R01565 +xref: MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-6797653 "DMGDH:FAD oxidatively demethylates DMGLY to SARC" +xref: RHEA:52856 +is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor + +[Term] +id: GO:0047866 +name: dimethylglycine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine." [EC:1.5.3.10, RHEA:17077] +synonym: "N,N-dimethylglycine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.10] +xref: EC:1.5.3.10 +xref: KEGG_REACTION:R01564 +xref: MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN +xref: RHEA:17077 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0047867 +name: dimethylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH." [EC:1.1.1.84, RHEA:13321] +synonym: "(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.84] +synonym: "beta,beta-dimethylmalate dehydrogenase activity" EXACT [EC:1.1.1.84] +xref: EC:1.1.1.84 +xref: KEGG_REACTION:R01211 +xref: MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN +xref: RHEA:13321 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047868 +name: dimethylmaleate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O." [EC:4.2.1.85, RHEA:20253] +synonym: "(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)" EXACT [EC:4.2.1.85] +synonym: "(2R,3S)-2,3-dimethylmalate hydro-lyase activity" EXACT [EC:4.2.1.85] +xref: EC:4.2.1.85 +xref: KEGG_REACTION:R03069 +xref: MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN +xref: RHEA:20253 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047869 +name: dimethylpropiothetin dethiomethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)." [EC:4.4.1.3, RHEA:19965] +synonym: "desulfhydrase activity" EXACT [EC:4.4.1.3] +synonym: "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)" EXACT [EC:4.4.1.3] +synonym: "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity" EXACT [EC:4.4.1.3] +xref: EC:4.4.1.3 +xref: KEGG_REACTION:R02574 +xref: MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN +xref: RHEA:19965 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0047870 +name: discadenine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+)." [EC:2.5.1.24, RHEA:19581] +synonym: "discadenine synthetase activity" EXACT [EC:2.5.1.24] +synonym: "S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity" EXACT [EC:2.5.1.24] +synonym: "S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas" RELATED [EC:2.5.1.24] +xref: EC:2.5.1.24 +xref: KEGG_REACTION:R03726 +xref: MetaCyc:DISCADENINE-SYNTHASE-RXN +xref: RHEA:19581 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0047871 +name: disulfoglucosamine-6-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate." [EC:3.1.6.11, RHEA:15517] +synonym: "6,N-disulfoglucosamine 6-O-sulfohydrolase activity" EXACT [EC:3.1.6.11] +synonym: "disulphoglucosamine-6-sulphatase activity" EXACT [] +synonym: "N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity" EXACT [EC:3.1.6.11] +synonym: "N-sulfoglucosamine-6-sulfatase activity" EXACT [EC:3.1.6.11] +xref: EC:3.1.6.11 +xref: KEGG_REACTION:R03216 +xref: MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN +xref: RHEA:15517 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0047872 +name: dolichol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate." [EC:2.3.1.123, MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN] +synonym: "acyl-CoA:dolichol acyltransferase activity" EXACT [EC:2.3.1.123] +synonym: "palmitoyl-CoA:dolichol O-palmitoyltransferase activity" EXACT [EC:2.3.1.123] +xref: EC:2.3.1.123 +xref: MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047873 +name: dolichyl-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate." [EC:3.1.3.51, MetaCyc:DOLICHYL-PHOSPHATASE-RXN] +synonym: "Dol-P phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "Dol-P-P phosphohydrolase activity" EXACT [] +synonym: "dolichol monophosphatase activity" EXACT [EC:3.1.3.51] +synonym: "dolichol phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "dolichol phosphate phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "dolichyl monophosphate phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "dolichyl phosphate phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "dolichyl pyrophosphate phosphatase activity" EXACT [] +synonym: "dolichyl-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.51] +synonym: "polyisoprenyl phosphate phosphatase activity" EXACT [EC:3.1.3.51] +synonym: "polyprenylphosphate phosphatase activity" EXACT [EC:3.1.3.51] +xref: EC:3.1.3.51 +xref: MetaCyc:DOLICHYL-PHOSPHATASE-RXN +xref: RHEA:13797 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047874 +name: dolichyldiphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate." [EC:3.6.1.43, MetaCyc:DOLICHYLDIPHOSPHATASE-RXN] +synonym: "dolichol diphosphatase activity" EXACT [EC:3.6.1.43] +synonym: "dolichyl diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.43] +synonym: "dolichyl pyrophosphatase activity" EXACT [EC:3.6.1.43] +synonym: "dolichyl-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.43] +xref: EC:3.6.1.43 +xref: MetaCyc:DOLICHYLDIPHOSPHATASE-RXN +xref: Reactome:R-HSA-446200 "DOLPP1 dephosphorylates DOLDP to DOLP" +xref: RHEA:14385 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0047875 +name: ecdysone oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2)." [EC:1.1.3.16, RHEA:11796] +synonym: "beta-ecdysone oxidase activity" EXACT [EC:1.1.3.16] +synonym: "ecdysone:oxygen 3-oxidoreductase activity" EXACT [EC:1.1.3.16] +xref: EC:1.1.3.16 +xref: KEGG_REACTION:R02373 +xref: MetaCyc:ECDYSONE-OXIDASE-RXN +xref: RHEA:11796 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047876 +name: endoglycosylceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose." [EC:3.2.1.123, MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN] +synonym: "EGCase activity" EXACT [EC:3.2.1.123] +synonym: "endo-glucosylceramidase activity" EXACT [EC:3.2.1.123] +synonym: "endoglycoceramidase activity" EXACT [EC:3.2.1.123] +synonym: "glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity" EXACT [EC:3.2.1.123] +synonym: "oligoglycosylglucosylceramide glycohydrolase activity" EXACT [EC:3.2.1.123] +xref: EC:3.2.1.123 +xref: MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047877 +name: ephedrine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH." [EC:1.5.1.18, RHEA:16289] +synonym: "(-)-ephedrine:NAD+ 2-oxidoreductase activity" EXACT [EC:1.5.1.18] +xref: EC:1.5.1.18 +xref: KEGG_REACTION:R03614 +xref: MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN +xref: RHEA:16289 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047878 +name: erythritol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+)." [EC:2.7.1.27, RHEA:20708] +synonym: "ATP:erythritol 4-phosphotransferase activity" EXACT [EC:2.7.1.27] +synonym: "erythritol kinase (phosphorylating)" EXACT [EC:2.7.1.27] +xref: EC:2.7.1.27 +xref: KEGG_REACTION:R02430 +xref: MetaCyc:ERYTHRITOL-KINASE-RXN +xref: RHEA:20708 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047879 +name: erythronolide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B." [EC:2.3.1.94, MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN] +synonym: "erythronolide condensing enzyme activity" EXACT [EC:2.3.1.94] +synonym: "malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.94] +xref: EC:2.3.1.94 +xref: MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN +xref: RHEA:23068 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047880 +name: erythrulose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH." [EC:1.1.1.162, RHEA:18005] +synonym: "D-erythrulose reductase activity" EXACT [EC:1.1.1.162] +synonym: "erythritol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.162] +xref: EC:1.1.1.162 +xref: KEGG_REACTION:R08573 +xref: MetaCyc:ERYTHRULOSE-REDUCTASE-RXN +xref: RHEA:18005 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047881 +name: estradiol 17-alpha-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+." [EC:1.1.1.148, MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN] +synonym: "17alpha-estradiol dehydrogenase activity" EXACT [EC:1.1.1.148] +synonym: "17alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.148] +synonym: "17alpha-hydroxy steroid oxidoreductase activity" EXACT [EC:1.1.1.148] +synonym: "17alpha-hydroxysteroid oxidoreductase activity" EXACT [EC:1.1.1.148] +synonym: "17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity" EXACT [EC:1.1.1.148] +synonym: "estradiol 17a-dehydrogenase activity" EXACT [] +synonym: "estradiol 17alpha-dehydrogenase activity" EXACT [EC:1.1.1.148] +synonym: "estradiol 17alpha-oxidoreductase activity" EXACT [EC:1.1.1.148] +xref: EC:1.1.1.148 +xref: MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047882 +name: estradiol 6-beta-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O." [EC:1.14.99.11, RHEA:19137] +synonym: "estradiol 6-beta-hydroxylase activity" EXACT [EC:1.14.99.11] +synonym: "estradiol 6b-hydroxylase activity" EXACT [] +synonym: "estradiol 6b-monooxygenase activity" EXACT [] +synonym: "estradiol 6beta-hydroxylase activity" EXACT [EC:1.14.99.11] +synonym: "estradiol 6beta-monooxygenase activity" EXACT [EC:1.14.99.11] +synonym: "estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)" EXACT [EC:1.14.99.11] +xref: EC:1.14.99.11 +xref: KEGG_REACTION:R03086 +xref: MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN +xref: RHEA:19137 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0047883 +name: ethanolamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2." [EC:1.4.3.8, MetaCyc:ETHANOLAMINE-OXIDASE-RXN] +synonym: "ethanolamine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.8] +xref: EC:1.4.3.8 +xref: MetaCyc:ETHANOLAMINE-OXIDASE-RXN +xref: RHEA:18581 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0047884 +name: FAD diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: FAD + H2O = AMP + FMN." [EC:3.6.1.18, MetaCyc:FAD-PYROPHOSPHATASE-RXN] +synonym: "FAD nucleotidohydrolase activity" EXACT [EC:3.6.1.18] +synonym: "FAD pyrophosphatase activity" EXACT [] +synonym: "FAD pyrophosphohydrolase activity" EXACT [GOC:tb] +synonym: "flavin adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] +synonym: "flavine adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] +synonym: "riboflavin adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] +synonym: "riboflavine adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] +xref: EC:3.6.1.18 +xref: MetaCyc:FAD-PYROPHOSPHATASE-RXN +xref: RHEA:13889 +is_a: GO:0004551 ! nucleotide diphosphatase activity + +[Term] +id: GO:0047885 +name: farnesol 2-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol." [EC:5.2.1.9, RHEA:13401] +synonym: "2-trans,6-trans-farnesol 2-cis-trans-isomerase activity" EXACT [EC:5.2.1.9] +synonym: "farnesol isomerase activity" EXACT [EC:5.2.1.9] +xref: EC:5.2.1.9 +xref: KEGG_REACTION:R03265 +xref: MetaCyc:FARNESOL-2-ISOMERASE-RXN +xref: RHEA:13401 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0047886 +name: farnesol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH." [EC:1.1.1.216, RHEA:14697] +synonym: "2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.216] +synonym: "farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.216] +synonym: "NADP-farnesol dehydrogenase activity" EXACT [EC:1.1.1.216] +xref: EC:1.1.1.216 +xref: KEGG_REACTION:R03264 +xref: MetaCyc:FARNESOL-DEHYDROGENASE-RXN +xref: RHEA:14697 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047887 +name: farnesyl diphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP." [EC:2.7.4.18, RHEA:21544] +synonym: "ATP:farnesyl-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.18] +synonym: "farnesyl pyrophosphate kinase activity" EXACT [EC:2.7.4.18] +synonym: "farnesyl-diphosphate kinase activity" EXACT [] +xref: EC:2.7.4.18 +xref: KEGG_REACTION:R02303 +xref: MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN +xref: RHEA:21544 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0047888 +name: fatty acid peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal." [EC:1.11.1.3, RHEA:23960] +synonym: "fatty-acid peroxidase activity" EXACT [] +synonym: "hexadecanoate:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.3] +synonym: "long chain fatty acid peroxidase activity" EXACT [EC:1.11.1.3] +xref: EC:1.11.1.3 +xref: KEGG_REACTION:R01703 +xref: MetaCyc:FATTY-ACID-PEROXIDASE-RXN +xref: RHEA:23960 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0047889 +name: ferredoxin-nitrate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin." [EC:1.7.7.2, MetaCyc:FERREDOXIN--NITRATE-REDUCTASE-RXN] +synonym: "assimilatory ferredoxin-nitrate reductase activity" EXACT [EC:1.7.7.2] +synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.7.2] +synonym: "nitrate (ferredoxin) reductase activity" EXACT [EC:1.7.7.2] +synonym: "nitrite:ferredoxin oxidoreductase activity" EXACT [EC:1.7.7.2] +xref: EC:1.7.7.2 +xref: MetaCyc:1.7.7.2-RXN +is_a: GO:0016664 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0047890 +name: flavanone 4-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH." [EC:1.1.1.234, MetaCyc:FLAVANONE-4-REDUCTASE-RXN] +synonym: "(2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.234] +synonym: "flavonone 4-reductase activity" EXACT [] +xref: EC:1.1.1.234 +xref: MetaCyc:FLAVANONE-4-REDUCTASE-RXN +xref: RHEA:11228 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047891 +name: flavone 7-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone." [EC:2.4.1.81, MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN] +synonym: "flavone 7-O-b-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose-apigenin beta-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "UDP-glucose-luteolin beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "UDPglucose-apigenin beta-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "UDPglucose-luteolin beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.81] +synonym: "uridine diphosphoglucose-luteolin glucosyltransferase activity" EXACT [EC:2.4.1.81] +xref: EC:2.4.1.81 +xref: MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:19577 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047892 +name: flavone apiosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone." [EC:2.4.2.25, MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN] +synonym: "UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity" EXACT [EC:2.4.2.25] +synonym: "UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity" EXACT [EC:2.4.2.25] +synonym: "uridine diphosphoapiose-flavone apiosyltransferase activity" EXACT [EC:2.4.2.25] +xref: EC:2.4.2.25 +xref: MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047893 +name: flavonol 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside." [EC:2.4.1.91, MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN] +synonym: "GTI" RELATED [EC:2.4.1.91] +synonym: "UDP-glucose flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] +synonym: "UDP-glucose:flavonol 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.91] +synonym: "UDP-glucose:flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] +synonym: "UDPG:flavonoid-3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] +synonym: "UDPglucose:flavonol 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.91] +synonym: "uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] +xref: EC:2.4.1.91 +xref: MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:22300 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047894 +name: flavonol 3-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate." [EC:2.8.2.25, RHEA:13453] +subset: goslim_chembl +synonym: "3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity" EXACT systematic_synonym [EC:2.8.2.25] +synonym: "flavonol 3-sulphotransferase activity" EXACT [] +xref: EC:2.8.2.25 +xref: KEGG_REACTION:R02159 +xref: MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN +xref: RHEA:13453 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0047895 +name: formaldehyde dismutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate." [EC:1.2.98.1, MetaCyc:FORMALDEHYDE-DISMUTASE-RXN] +synonym: "aldehyde dismutase activity" EXACT [EC:1.2.98.1] +synonym: "cannizzanase activity" EXACT [EC:1.2.98.1] +synonym: "formaldehyde:formaldehyde oxidoreductase activity" EXACT [EC:1.2.98.1] +synonym: "nicotinoprotein aldehyde dismutase" EXACT [EC:1.2.98.1] +xref: EC:1.2.98.1 +xref: MetaCyc:FORMALDEHYDE-DISMUTASE-RXN +xref: RHEA:19221 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0047896 +name: formaldehyde transketolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone." [EC:2.2.1.3, MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN] +synonym: "D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity" EXACT [EC:2.2.1.3] +synonym: "DHAS activity" EXACT [EC:2.2.1.3] +synonym: "dihydroxyacetone synthase activity" EXACT [EC:2.2.1.3] +synonym: "glycerone synthase activity" EXACT [EC:2.2.1.3] +xref: EC:2.2.1.3 +xref: MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN +xref: RHEA:24264 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0047897 +name: formate-dihydrofolate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate." [EC:6.3.4.17, RHEA:24328] +synonym: "dihydrofolate formyltransferase activity" EXACT [EC:6.3.4.17] +synonym: "formate:dihydrofolate ligase (ADP-forming)" EXACT [EC:6.3.4.17] +synonym: "formyl dihydrofolate synthase activity" EXACT [EC:6.3.4.17] +xref: EC:6.3.4.17 +xref: KEGG_REACTION:R02238 +xref: MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN +xref: RHEA:24328 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0047898 +name: formate dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1." [EC:1.2.2.1, MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN] +synonym: "formate:cytochrome b1 oxidoreductase activity" EXACT [EC:1.2.2.1] +synonym: "formate:ferricytochrome-b1 oxidoreductase activity" EXACT [EC:1.2.2.1] +xref: EC:1.2.2.1 +xref: MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN +is_a: GO:0016622 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor + +[Term] +id: GO:0047899 +name: formate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH." [EC:1.17.1.10, RHEA:12000] +synonym: "formate:NADP+ oxidoreductase activity" EXACT [EC:1.17.1.10] +synonym: "NADP-dependent formate dehydrogenase activity" EXACT [EC:1.17.1.10] +xref: EC:1.17.1.10 +xref: KEGG_REACTION:R00134 +xref: MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:12000 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047900 +name: formate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+)." [EC:2.7.2.6, RHEA:16009] +synonym: "ATP:formate phosphotransferase activity" EXACT [EC:2.7.2.6] +xref: EC:2.7.2.6 +xref: KEGG_REACTION:R00518 +xref: MetaCyc:FORMATE-KINASE-RXN +xref: RHEA:16009 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0047901 +name: formyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+)." [EC:3.1.2.10, RHEA:19741] +synonym: "formyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.10] +xref: EC:3.1.2.10 +xref: KEGG_REACTION:R00521 +xref: MetaCyc:FORMYL-COA-HYDROLASE-RXN +xref: RHEA:19741 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0047902 +name: formylaspartate deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate." [EC:3.5.1.8, MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN] +synonym: "formylaspartic formylase (formylase I, formylase II)" EXACT [EC:3.5.1.8] +synonym: "N-formyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.8] +xref: EC:3.5.1.8 +xref: MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN +xref: RHEA:22040 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047903 +name: fructose 5-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH." [EC:1.1.1.124, MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN] +synonym: "5-keto-D-fructose reductase (NADP+)" EXACT [EC:1.1.1.124] +synonym: "5-ketofructose reductase (NADP(+)) activity" EXACT [EC:1.1.1.124] +synonym: "5-ketofructose reductase (NADP)" EXACT [EC:1.1.1.124] +synonym: "5-ketofructose reductase (NADP+) activity" EXACT [EC:1.1.1.124] +synonym: "D-(-)fructose:(NADP+) 5-oxidoreductase activity" EXACT [EC:1.1.1.124] +synonym: "D-fructose:NADP+ 5-oxidoreductase activity" EXACT [EC:1.1.1.124] +synonym: "fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.124] +xref: EC:1.1.1.124 +xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN +xref: RHEA:14069 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047904 +name: fructose 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2)." [EC:1.1.99.11, RHEA:22304] +synonym: "D-fructose dehydrogenase activity" EXACT [EC:1.1.99.11] +synonym: "D-fructose:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.11] +synonym: "D-fructose:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.11] +synonym: "fructose 5-dehydrogenase (acceptor)" EXACT [EC:1.1.99.11] +xref: EC:1.1.99.11 +xref: KEGG_REACTION:R00873 +xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN +xref: RHEA:22304 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047905 +name: fructose-6-phosphate phosphoketolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O." [EC:4.1.2.22, MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN] +synonym: "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)" EXACT [EC:4.1.2.22] +synonym: "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity" EXACT [EC:4.1.2.22] +xref: EC:4.1.2.22 +xref: MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN +xref: RHEA:12196 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047906 +name: fucosterol-epoxide lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol." [EC:4.1.2.33, RHEA:10884] +synonym: "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)" EXACT [EC:4.1.2.33] +synonym: "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity" EXACT [EC:4.1.2.33] +xref: EC:4.1.2.33 +xref: KEGG_REACTION:R03723 +xref: MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN +xref: RHEA:10884 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0047907 +name: furylfuramide isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide." [EC:5.2.1.6, RHEA:21848] +synonym: "2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity" EXACT [EC:5.2.1.6] +xref: EC:5.2.1.6 +xref: KEGG_REACTION:R04538 +xref: MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN +xref: RHEA:21848 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0047908 +name: fusarinine-C ornithinesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol." [EC:3.1.1.48, MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN] +synonym: "5-N-acyl-L-ornithine-ester hydrolase activity" EXACT [EC:3.1.1.48] +synonym: "N5-acyl-L-ornithine-ester hydrolase activity" EXACT [EC:3.1.1.48] +synonym: "ornithine esterase activity" EXACT [EC:3.1.1.48] +xref: EC:3.1.1.48 +xref: MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047909 +name: galactolipid O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol." [EC:2.3.1.134, MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN] +synonym: "galactolipid:galactolipid acyltransferase activity" EXACT [EC:2.3.1.134] +synonym: "mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity" EXACT [EC:2.3.1.134] +xref: EC:2.3.1.134 +xref: MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN +is_a: GO:0008374 ! O-acyltransferase activity + +[Term] +id: GO:0047910 +name: galactose 1-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH." [EC:1.1.1.120, MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN] +synonym: "D-galactose dehydrogenase (NADP+)" EXACT [EC:1.1.1.120] +synonym: "D-galactose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.120] +xref: EC:1.1.1.120 +xref: MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN +xref: RHEA:18625 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047911 +name: galacturan 1,4-alpha-galacturonidase activity +namespace: molecular_function +def: "Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate." [EC:3.2.1.67, MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN] +synonym: "exo-D-galacturonanase activity" EXACT [EC:3.2.1.67] +synonym: "exo-D-galacturonase activity" EXACT [] +synonym: "exo-polygalacturonase activity" EXACT [] +synonym: "exopoly-D-galacturonase activity" EXACT [] +synonym: "exopolygalacturonase activity" EXACT [EC:3.2.1.67] +synonym: "galacturan alpha-1,4-galacturonidase activity" EXACT [] +synonym: "poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity" EXACT [EC:3.2.1.67] +synonym: "poly(galacturonate) hydrolase activity" EXACT [EC:3.2.1.67] +xref: EC:3.2.1.67 +xref: MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047912 +name: galacturonokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+)." [EC:2.7.1.44, RHEA:12965] +synonym: "ATP:D-galacturonate 1-phosphotransferase activity" EXACT [EC:2.7.1.44] +synonym: "galacturonokinase (phosphorylating) D-galacturonic acid kinase activity" EXACT [EC:2.7.1.44] +xref: EC:2.7.1.44 +xref: KEGG_REACTION:R01980 +xref: MetaCyc:GALACTURONOKINASE-RXN +xref: RHEA:12965 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047913 +name: gallate 1-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP." [EC:2.4.1.136, RHEA:15249] +synonym: "gallate 1-b-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose-vanillate 1-glucosyltransferase activity" EXACT [EC:2.4.1.136] +synonym: "UDP-glucose:gallate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.136] +synonym: "UDPglucose-vanillate 1-glucosyltransferase activity" EXACT [EC:2.4.1.136] +synonym: "UDPglucose:gallate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.136] +synonym: "UDPglucose:gallate glucosyltransferase activity" EXACT [EC:2.4.1.136] +synonym: "UDPglucose:vanillate 1-O-glucosyltransferase activity" EXACT [EC:2.4.1.136] +xref: EC:2.4.1.136 +xref: KEGG_REACTION:R03297 +xref: MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:15249 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047914 +name: gamma-glutamylhistamine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown." [EC:6.3.2.18, MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN] +synonym: "g-glutamylhistamine synthase activity" EXACT [] +synonym: "gamma-GHA synthetase activity" EXACT [EC:6.3.2.18] +synonym: "gamma-glutaminylhistamine synthetase activity" EXACT [EC:6.3.2.18] +synonym: "L-glutamate:histamine ligase activity" EXACT [EC:6.3.2.18] +xref: EC:6.3.2.18 +xref: MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047915 +name: ganglioside galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine." [EC:2.4.1.62, MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN] +synonym: "GM1-synthase activity" EXACT [EC:2.4.1.62] +synonym: "UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDP-galactose-GM2 galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDP-galactose-GM2 ganglioside galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDPgalactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "uridine diphosphate D-galactose:glycolipid galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "uridine diphosphogalactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] +synonym: "uridine diphosphogalactose-GM2 galactosyltransferase activity" EXACT [EC:2.4.1.62] +xref: EC:2.4.1.62 +xref: MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN +xref: RHEA:16773 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0047916 +name: GDP-6-deoxy-D-talose 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+." [EC:1.1.1.135, MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN] +synonym: "GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity" EXACT [EC:1.1.1.135] +synonym: "guanosine diphospho-6-deoxy-D-talose dehydrogenase activity" EXACT [EC:1.1.1.135] +xref: EC:1.1.1.135 +xref: MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047917 +name: GDP-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+)." [EC:3.2.1.42, RHEA:15049] +synonym: "GDP-glucose glucohydrolase activity" EXACT [EC:3.2.1.42] +synonym: "GDPglucose glucohydrolase activity" EXACT [EC:3.2.1.42] +synonym: "GDPglucosidase activity" EXACT [EC:3.2.1.42] +synonym: "guanosine diphosphate D-glucose glucohydrolase activity" EXACT [EC:3.2.1.42] +synonym: "guanosine diphosphoglucosidase activity" EXACT [EC:3.2.1.42] +xref: EC:3.2.1.42 +xref: KEGG_REACTION:R00337 +xref: MetaCyc:GDP-GLUCOSIDASE-RXN +xref: RHEA:15049 +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0047918 +name: GDP-mannose 3,5-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose = GDP-L-galactose." [EC:5.1.3.18] +synonym: "GDP-D-mannose:GDP-L-galactose epimerase activity" EXACT [EC:5.1.3.18] +synonym: "GDPmannose 3,5-epimerase activity" EXACT [EC:5.1.3.18] +synonym: "guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity" EXACT [EC:5.1.3.18] +xref: EC:5.1.3.18 +xref: MetaCyc:RXN-1882 +xref: RHEA:11144 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047919 +name: GDP-mannose 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH." [EC:1.1.1.132, RHEA:21728] +synonym: "GDP mannose dehydrogenase activity" EXACT [EC:1.1.1.132] +synonym: "GDP-D-mannose:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.132] +synonym: "GDPmannose 6-dehydrogenase activity" EXACT [EC:1.1.1.132] +synonym: "guanosine diphospho-D-mannose dehydrogenase activity" EXACT [EC:1.1.1.132] +synonym: "guanosine diphosphomannose dehydrogenase activity" EXACT [EC:1.1.1.132] +xref: EC:1.1.1.132 +xref: KEGG_REACTION:R00880 +xref: MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN +xref: RHEA:21728 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047920 +name: geissoschizine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH." [EC:1.3.1.36, RHEA:11376] +synonym: "geissoschizine:NADP+ 4,21-oxidoreductase activity" EXACT [EC:1.3.1.36] +xref: EC:1.3.1.36 +xref: KEGG_REACTION:R03860 +xref: MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN +xref: RHEA:11376 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047921 +name: aminoglycoside 2'-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring." [EC:2.3.1.59, RHEA:24516] +synonym: "acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity" NARROW [EC:2.3.1.59] +synonym: "acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity" NARROW [EC:2.3.1.59] +synonym: "gentamicin 2'-N-acetyltransferase activity" NARROW [] +synonym: "gentamicin acetyltransferase II activity" NARROW [EC:2.3.1.59] +synonym: "gentamycin 2'-N-acetyltransferase activity" NARROW [] +synonym: "gentamycin acetyltransferase II" RELATED [EC:2.3.1.59] +xref: EC:2.3.1.59 +xref: KEGG_REACTION:R03056 +xref: MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN +xref: RHEA:24516 +is_a: GO:0034069 ! aminoglycoside N-acetyltransferase activity + +[Term] +id: GO:0047922 +name: gentisate 1,2-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+)." [EC:1.13.11.4, RHEA:18237] +synonym: "2,5-dihydroxybenzoate dioxygenase activity" EXACT [EC:1.13.11.4] +synonym: "gentisate dioxygenase activity" EXACT [EC:1.13.11.4] +synonym: "gentisate oxygenase activity" EXACT [EC:1.13.11.4] +synonym: "gentisate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.4] +synonym: "gentisic acid oxidase activity" EXACT [EC:1.13.11.4] +xref: EC:1.13.11.4 +xref: KEGG_REACTION:R02656 +xref: MetaCyc:GENTISATE-12-DIOXYGENASE-RXN +xref: RHEA:18237 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0047923 +name: gentisate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone." [EC:4.1.1.62, RHEA:21312] +synonym: "2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)" EXACT [EC:4.1.1.62] +synonym: "2,5-dihydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.62] +synonym: "gentisate carboxy-lyase activity" EXACT [EC:4.1.1.62] +xref: EC:4.1.1.62 +xref: KEGG_REACTION:R02489 +xref: MetaCyc:GENTISATE-DECARBOXYLASE-RXN +xref: RHEA:21312 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047924 +name: geraniol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH." [EC:1.1.1.183, MetaCyc:GERANIOL-DEHYDROGENASE-RXN] +synonym: "geraniol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.183] +xref: EC:1.1.1.183 +xref: MetaCyc:GERANIOL-DEHYDROGENASE-RXN +xref: RHEA:14521 +xref: UM-BBD_reactionID:r1163 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047925 +name: geranoyl-CoA carboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate." [EC:6.4.1.5, RHEA:17701] +synonym: "geranoyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.5] +synonym: "geranoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.5] +synonym: "geranyl-CoA carboxylase activity" EXACT [EC:6.4.1.5] +xref: EC:6.4.1.5 +xref: KEGG_REACTION:R03494 +xref: MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN +xref: RHEA:17701 +xref: UM-BBD_reactionID:r1166 +is_a: GO:0016421 ! CoA carboxylase activity + +[Term] +id: GO:0047926 +name: geranyl-diphosphate cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate." [EC:5.5.1.8, RHEA:18209] +synonym: "(+)-bornyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.8] +synonym: "(+)-bornylpyrophosphate cyclase activity" EXACT [EC:5.5.1.8] +synonym: "bornyl diphosphate synthase activity" EXACT [EC:5.5.1.8] +synonym: "bornyl pyrophosphate synthase activity" EXACT [EC:5.5.1.8] +synonym: "bornyl pyrophosphate synthetase activity" EXACT [EC:5.5.1.8] +xref: EC:5.5.1.8 +xref: KEGG_REACTION:R02007 +xref: MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN +xref: RHEA:18209 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0047927 +name: gibberellin-44 dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2." [EC:1.14.11.12, MetaCyc:GIBBERELLIN-44-DIOXYGENASE-RXN] +synonym: "(gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.12] +synonym: "(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.12] +synonym: "gibberellin A44 oxidase activity" EXACT [EC:1.14.11.12] +synonym: "oxygenase, gibberellin A44 oxidase activity" EXACT [EC:1.14.11.12] +xref: EC:1.14.11.12 +xref: MetaCyc:RXN1F-168 +xref: RHEA:16033 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0047928 +name: gibberellin beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside." [EC:2.4.1.176, MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN] +synonym: "gibberellin b-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.176] +synonym: "UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.176] +synonym: "uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.176] +synonym: "uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity" EXACT [EC:2.4.1.176] +xref: EC:2.4.1.176 +xref: MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:20025 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0047929 +name: gluconate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O." [EC:4.2.1.39, RHEA:21612] +synonym: "D-gluconate dehydratase activity" EXACT [EC:4.2.1.39] +synonym: "D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.2.1.39] +synonym: "D-gluconate hydro-lyase activity" EXACT [EC:4.2.1.39] +xref: EC:4.2.1.39 +xref: KEGG_REACTION:R01538 +xref: MetaCyc:GLUCONATE-DEHYDRATASE-RXN +xref: RHEA:21612 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047930 +name: glucosaminate ammonia-lyase activity +namespace: molecular_function +alt_id: GO:0050443 +def: "Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3." [EC:4.3.1.9, MetaCyc:GLUCOSAMINATE-AMMONIA-LYASE-RXN] +comment: Note that this function was EC:4.3.1.21. +synonym: "2-amino-2-deoxy-D-gluconate ammonia-lyase activity" EXACT [EC:4.3.1.9] +synonym: "2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.9] +synonym: "acetylenemonocarboxylic acid hydrase activity" EXACT [EC:4.3.1.9] +synonym: "aminodeoxygluconate ammonia-lyase activity" EXACT [] +synonym: "aminodeoxygluconate dehydratase activity" EXACT [] +synonym: "D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.3.1.9] +synonym: "D-glucosaminate ammonia-lyase activity" EXACT [EC:4.3.1.9] +synonym: "D-glucosaminate dehydratase activity" EXACT [EC:4.3.1.9] +synonym: "D-glucosaminic acid dehydrase activity" EXACT [EC:4.3.1.9] +synonym: "glucosaminic dehydrase activity" EXACT [EC:4.3.1.9] +xref: EC:4.3.1.9 +xref: MetaCyc:4.3.1.21-RXN +xref: RHEA:12488 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0047931 +name: glucosamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate." [EC:2.7.1.8, MetaCyc:GLUCOSAMINE-KINASE-RXN] +synonym: "aminodeoxyglucose kinase activity" EXACT [EC:2.7.1.8] +synonym: "ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity" EXACT [EC:2.7.1.8] +synonym: "ATP:D-glucosamine phosphotransferase activity" EXACT [EC:2.7.1.8] +synonym: "glucosamine kinase (phosphorylating)" EXACT [EC:2.7.1.8] +xref: EC:2.7.1.8 +xref: MetaCyc:GLUCOSAMINE-KINASE-RXN +xref: RHEA:10948 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047932 +name: glucosamine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+)." [EC:2.3.1.3, RHEA:21332] +synonym: "acetyl-CoA:D-glucosamine N-acetyltransferase activity" EXACT [EC:2.3.1.3] +synonym: "glucosamine acetylase activity" EXACT [EC:2.3.1.3] +synonym: "glucosamine acetyltransferase activity" EXACT [EC:2.3.1.3] +xref: EC:2.3.1.3 +xref: KEGG_REACTION:R01204 +xref: MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:21332 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047933 +name: glucose-1,6-bisphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+)." [EC:2.7.1.106, RHEA:16769] +synonym: "3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.106] +synonym: "3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.106] +synonym: "glucose 1,6-diphosphate synthase activity" EXACT [EC:2.7.1.106] +synonym: "glucose-1,6-bisphosphate synthetase activity" EXACT [EC:2.7.1.106] +xref: EC:2.7.1.106 +xref: KEGG_REACTION:R01660 +xref: MetaCyc:GLUCOSE-16-BISPHOSPHATE-SYNTHASE-RXN +xref: Reactome:R-HSA-8955760 "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP" +xref: RHEA:16769 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047934 +name: glucose 1-dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH." [EC:1.1.1.118, MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN] +synonym: "D-aldohexose dehydrogenase activity" EXACT [EC:1.1.1.118] +synonym: "D-glucose:NAD oxidoreductase activity" EXACT [EC:1.1.1.118] +synonym: "D-glucose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.118] +xref: EC:1.1.1.118 +xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN +xref: RHEA:14293 +is_a: GO:0047936 ! glucose 1-dehydrogenase [NAD(P)] activity + +[Term] +id: GO:0047935 +name: glucose 1-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH." [EC:1.1.1.119, MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN] +synonym: "D-glucose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.119] +synonym: "NADP-dependent glucose dehydrogenase activity" EXACT [EC:1.1.1.119] +synonym: "NADP-linked aldohexose dehydrogenase activity" EXACT [EC:1.1.1.119] +synonym: "nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity" EXACT [EC:1.1.1.119] +xref: EC:1.1.1.119 +xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN +xref: RHEA:14405 +is_a: GO:0047936 ! glucose 1-dehydrogenase [NAD(P)] activity + +[Term] +id: GO:0047936 +name: glucose 1-dehydrogenase [NAD(P)] activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H." [EC:1.1.1.47, MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN] +synonym: "beta-D-glucose:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.47] +synonym: "D-glucose dehydrogenase (NAD(P))" EXACT [EC:1.1.1.47] +synonym: "hexose phosphate dehydrogenase activity" EXACT [EC:1.1.1.47] +xref: EC:1.1.1.47 +xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN +is_a: GO:0004344 ! glucose dehydrogenase activity + +[Term] +id: GO:0047937 +name: glucose-1-phosphate phosphodismutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate." [EC:2.7.1.41, MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN] +synonym: "D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.41] +synonym: "glucose 1-phosphate transphosphorylase activity" EXACT [EC:2.7.1.41] +synonym: "phosphodismutase activity" EXACT [EC:2.7.1.41] +xref: EC:2.7.1.41 +xref: MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN +xref: RHEA:16397 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047938 +name: glucose-6-phosphate 1-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate." [EC:5.1.3.15, MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN] +synonym: "D-glucose-6-phosphate 1-epimerase activity" EXACT [EC:5.1.3.15] +synonym: "glucose-6 phosphate 1-epimerase activity" EXACT [] +xref: EC:5.1.3.15 +xref: MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN +xref: RHEA:16249 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0047939 +name: L-glucuronate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH." [EC:1.1.1.19, RHEA:14909] +synonym: "aldehyde reductase II activity" RELATED [EC:1.1.1.19] +synonym: "D-glucuronate dehydrogenase activity" EXACT [EC:1.1.1.19] +synonym: "D-glucuronate reductase activity" NARROW [EC:1.1.1.19] +synonym: "glucuronate dehydrogenase activity" EXACT [EC:1.1.1.19] +synonym: "glucuronate reductase activity" EXACT [] +synonym: "NADP-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.19] +synonym: "TPN-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.19] +xref: EC:1.1.1.19 +xref: KEGG_REACTION:R01481 +xref: MetaCyc:GLUCURONATE-REDUCTASE-RXN +xref: Reactome:R-HSA-5661256 "AKR1A1 reduces D-glucuronate to L-gulonate" +xref: RHEA:14909 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047940 +name: glucuronokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+)." [EC:2.7.1.43, RHEA:17005] +synonym: "ATP:D-glucuronate 1-phosphotransferase activity" EXACT [EC:2.7.1.43] +synonym: "glucurono-glucuronokinase activity" EXACT [EC:2.7.1.43] +synonym: "glucuronokinase (phosphorylating)" EXACT [EC:2.7.1.43] +xref: EC:2.7.1.43 +xref: KEGG_REACTION:R01476 +xref: MetaCyc:GLUCURONOKINASE-RXN +xref: RHEA:17005 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047941 +name: glucuronolactone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH." [EC:1.1.1.20, RHEA:18925] +xref: EC:1.1.1.20 +xref: KEGG_REACTION:R03183 +xref: MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN +xref: RHEA:18925 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047942 +name: glutamate-ethylamine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate." [EC:6.3.1.6, RHEA:20525] +synonym: "L-glutamate:ethylamine ligase (ADP-forming)" EXACT [EC:6.3.1.6] +synonym: "N(5)-ethyl-L-glutamine synthetase activity" EXACT [EC:6.3.1.6] +synonym: "N5-ethyl-L-glutamine synthetase activity" EXACT [EC:6.3.1.6] +synonym: "N5-ethylglutamine synthetase activity" EXACT [EC:6.3.1.6] +synonym: "theanine synthetase activity" EXACT [EC:6.3.1.6] +xref: EC:6.3.1.6 +xref: KEGG_REACTION:R02929 +xref: MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN +xref: RHEA:20525 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0047943 +name: glutamate-methylamine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate." [EC:6.3.4.12, RHEA:17117] +synonym: "gamma-glutamylmethylamide synthetase activity" EXACT [EC:6.3.4.12] +synonym: "L-glutamate:methylamine ligase (ADP-forming)" EXACT [EC:6.3.4.12] +xref: EC:6.3.4.12 +xref: KEGG_REACTION:R01585 +xref: MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN +xref: RHEA:17117 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0047944 +name: glutamate 1-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+)." [EC:2.7.2.13, RHEA:17217] +synonym: "ATP:L-glutamate 1-phosphotransferase activity" EXACT [EC:2.7.2.13] +xref: EC:2.7.2.13 +xref: KEGG_REACTION:R00241 +xref: MetaCyc:GLUTAMATE-1-KINASE-RXN +xref: RHEA:17217 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0047945 +name: L-glutamine:pyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine." [EC:2.6.1.15, RHEA:10400] +synonym: "gamma-glutaminyltransferase activity" RELATED [EC:2.6.1.15] +synonym: "glutaminase II activity" RELATED [EC:2.6.1.15] +synonym: "glutamine transaminase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine transaminase L activity" BROAD [EC:2.6.1.15] +synonym: "glutamine--oxo-acid transaminase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine--pyruvate aminotransferase activity" BROAD [] +synonym: "glutamine-alpha-keto acid transamidase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine-alpha-keto acid transaminase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine-keto acid aminotransferase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine-oxo acid aminotransferase activity" BROAD [EC:2.6.1.15] +synonym: "glutamine-pyruvate transaminase activity" BROAD [EC:2.6.1.15] +synonym: "L-glutamine transaminase L" RELATED [EC:2.6.1.15] +xref: EC:2.6.1.15 +xref: KEGG_REACTION:R00576 +xref: MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN +xref: Reactome:R-HSA-893616 "glutamine + pyruvate => 2-oxoglutaramate + alanine" +xref: RHEA:10400 +is_a: GO:0070548 ! L-glutamine aminotransferase activity + +[Term] +id: GO:0047946 +name: glutamine N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine." [EC:2.3.1.68, MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN] +synonym: "acyl-CoA:L-glutamine N-acyltransferase activity" EXACT [EC:2.3.1.68] +xref: EC:2.3.1.68 +xref: MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0047947 +name: glutamine N-phenylacetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine." [EC:2.3.1.14, MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN] +synonym: "glutamine phenylacetyltransferase activity" EXACT [EC:2.3.1.14] +synonym: "phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity" EXACT [EC:2.3.1.14] +synonym: "phenylacetyl-CoA:L-glutamine N-acetyltransferase activity" EXACT [EC:2.3.1.14] +xref: EC:2.3.1.14 +xref: MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN +xref: RHEA:21844 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047948 +name: glutarate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate." [EC:6.2.1.6, RHEA:14169] +synonym: "glutarate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.6] +synonym: "glutaryl coenzyme A synthetase activity" EXACT [EC:6.2.1.6] +synonym: "glutaryl-CoA synthetase activity" EXACT [EC:6.2.1.6] +xref: EC:6.2.1.6 +xref: KEGG_REACTION:R02402 +xref: MetaCyc:GLUTARATE--COA-LIGASE-RXN +xref: RHEA:14169 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0047949 +name: glutarate-semialdehyde dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH." [EC:1.2.1.20, MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN] +synonym: "glutarate semialdehyde dehydrogenase (NAD+) activity" EXACT [] +synonym: "glutarate-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.20] +xref: EC:1.2.1.20 +xref: MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN +xref: RHEA:12064 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047950 +name: glutathione oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2)." [EC:1.8.3.3, RHEA:24112] +synonym: "glutathione:oxygen oxidoreductase activity" EXACT [EC:1.8.3.3] +xref: EC:1.8.3.3 +xref: KEGG_REACTION:R00120 +xref: MetaCyc:GLUTATHIONE-OXIDASE-RXN +xref: RHEA:24112 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0047951 +name: glutathione thiolesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+)." [EC:3.1.2.7, RHEA:22708] +synonym: "citryl-glutathione thioesterhydrolase activity" EXACT [EC:3.1.2.7] +synonym: "glutathione thioesterase activity" EXACT [] +synonym: "S-acylglutathione hydrolase activity" EXACT [EC:3.1.2.7] +xref: EC:3.1.2.7 +xref: KEGG_REACTION:R00547 +xref: MetaCyc:GLUTATHIONE-THIOESTERASE-RXN +xref: RHEA:22708 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0047952 +name: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +alt_id: GO:0036439 +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+." [EC:1.1.1.94, MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN, RHEA:11096] +synonym: "glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.1.1.94] +synonym: "glycerol-3-phosphate dehydrogenase (NAD(P)+) activity" EXACT [] +synonym: "L-glycerol-3-phosphate:NAD(P) oxidoreductase activity" EXACT [EC:1.1.1.94] +synonym: "sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.94] +xref: EC:1.1.1.94 +xref: KEGG_REACTION:R00844 +xref: MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN +xref: RHEA:11096 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: bf +creation_date: 2013-09-30T10:37:46Z + +[Term] +id: GO:0047953 +name: glycerol 2-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH." [EC:1.1.1.156, RHEA:12753] +synonym: "DHA oxidoreductase activity" EXACT [EC:1.1.1.156] +synonym: "dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.156] +synonym: "dihydroxyacetone reductase (NADPH)" EXACT [EC:1.1.1.156] +synonym: "dihydroxyacetone reductase activity" EXACT [EC:1.1.1.156] +synonym: "glycerol:NADP+ 2-oxidoreductase (glycerone-forming)" EXACT [EC:1.1.1.156] +xref: EC:1.1.1.156 +xref: KEGG_REACTION:R01039 +xref: MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN +xref: RHEA:12753 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047954 +name: glycerol-2-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate." [EC:3.1.3.19, RHEA:13105] +synonym: "2-glycerophosphatase activity" EXACT [EC:3.1.3.19] +synonym: "beta-glycerophosphatase activity" EXACT [EC:3.1.3.19] +synonym: "beta-glycerophosphate phosphatase activity" EXACT [EC:3.1.3.19] +synonym: "glycerol-2-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.19] +xref: EC:3.1.3.19 +xref: KEGG_REACTION:R01043 +xref: MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN +xref: RHEA:13105 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0047955 +name: glycerol dehydrogenase (acceptor) activity +namespace: molecular_function +def: "Catalysis of the reaction: A + glycerol = AH(2) + glycerone." [EC:1.1.99.22, RHEA:17493] +synonym: "glycerol:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.22] +synonym: "glycerol:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.22] +xref: EC:1.1.99.22 +xref: KEGG_REACTION:R01045 +xref: MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN +xref: RHEA:17493 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047956 +name: glycerol dehydrogenase [NADP+] activity +namespace: molecular_function +def: "Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH." [EC:1.1.1.72, MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN] +synonym: "glycerol dehydrogenase (NADP+) activity" RELATED [] +synonym: "glycerol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.72] +xref: EC:1.1.1.72 +xref: MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN +xref: RHEA:23592 +is_a: GO:1990042 ! glycerol dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0047957 +name: 4'-methoxyisoflavone 2'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O." [EC:1.14.14.89, MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN] +synonym: "formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)" EXACT [EC:1.14.14.89] +synonym: "isoflavone 2'-monooxygenase activity" BROAD [EC:1.14.14.89] +xref: EC:1.14.14.89 +xref: MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN +xref: RHEA:12388 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0047958 +name: glycine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate." [EC:2.6.1.4, MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN] +synonym: "glutamate-glyoxylate transaminase activity" EXACT [] +synonym: "glutamic-glyoxylic transaminase activity" EXACT [EC:2.6.1.4] +synonym: "glycine aminotransferase activity" BROAD [] +synonym: "glycine transaminase activity" BROAD [EC:2.6.1.4] +synonym: "glyoxylate-glutamate aminotransferase activity" EXACT [EC:2.6.1.4] +synonym: "glyoxylate-glutamic transaminase activity" EXACT [EC:2.6.1.4] +synonym: "L-glutamate:glyoxylate aminotransferase activity" EXACT [] +xref: EC:2.6.1.4 +xref: MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN +xref: RHEA:14089 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0047959 +name: glycine dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c." [EC:1.4.2.1, MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN] +synonym: "glycine-cytochrome c reductase activity" EXACT [EC:1.4.2.1] +synonym: "glycine:ferricytochrome-c oxidoreductase (deaminating)" EXACT [EC:1.4.2.1] +synonym: "reductase, glycine-cytochrome c" EXACT [EC:1.4.2.1] +xref: EC:1.4.2.1 +xref: MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN +is_a: GO:0016640 ! oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor + +[Term] +id: GO:0047960 +name: glycine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH." [EC:1.4.1.10, MetaCyc:GLYCINE-DEHYDROGENASE-RXN] +synonym: "glycine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.10] +xref: EC:1.4.1.10 +xref: MetaCyc:GLYCINE-DEHYDROGENASE-RXN +xref: RHEA:15721 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047961 +name: glycine N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine." [EC:2.3.1.13, MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN] +synonym: "acyl-CoA:glycine N-acyltransferase activity" EXACT [EC:2.3.1.13] +synonym: "glycine acyltransferase activity" EXACT [EC:2.3.1.13] +synonym: "glycine-N-acylase activity" EXACT [EC:2.3.1.13] +xref: EC:2.3.1.13 +xref: MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-2534040 "Unknown NAT N-acylates Gly in GNAT1" +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0047962 +name: glycine N-benzoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)." [EC:2.3.1.71, RHEA:18493] +synonym: "benzoyl CoA-amino acid N-acyltransferase activity" EXACT [EC:2.3.1.71] +synonym: "benzoyl-CoA:glycine N-acyltransferase activity" EXACT [EC:2.3.1.71] +synonym: "benzoyl-CoA:glycine N-benzoyltransferase activity" EXACT [EC:2.3.1.71] +xref: EC:2.3.1.71 +xref: KEGG_REACTION:R02452 +xref: MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN +xref: Reactome:R-HSA-159566 "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A" +xref: Reactome:R-HSA-159574 "salicylate-CoA + glycine => salicyluric acid + Coenzyme A" +xref: RHEA:18493 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047963 +name: glycine N-choloyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate." [EC:2.3.1.65, MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN] +synonym: "amino acid N-choloyltransferase activity" EXACT [EC:2.3.1.65] +synonym: "BACAT activity" EXACT [EC:2.3.1.65] +synonym: "BAT activity" EXACT [EC:2.3.1.65] +synonym: "bile acid-CoA:amino acid N-acyltransferase activity" EXACT [EC:2.3.1.65] +synonym: "choloyl-CoA:glycine N-choloyltransferase activity" EXACT [EC:2.3.1.65] +synonym: "cholyl-CoA glycine-taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] +synonym: "cholyl-CoA:taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] +synonym: "glycine--taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] +xref: EC:2.3.1.65 +xref: MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN +xref: RHEA:14001 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0047964 +name: glyoxylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH." [EC:1.1.1.26, MetaCyc:GLYCOLATE-REDUCTASE-RXN] +synonym: "glycolate reductase activity" EXACT [] +synonym: "glyoxylic acid reductase activity" EXACT [EC:1.1.1.26] +synonym: "NADH-dependent glyoxylate reductase activity" EXACT [EC:1.1.1.26] +xref: EC:1.1.1.26 +xref: MetaCyc:GLYCOLATE-REDUCTASE-RXN +xref: RHEA:18229 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047965 +name: glycoprotein O-fatty-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein." [EC:2.3.1.142, MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN] +synonym: "fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity" EXACT [EC:2.3.1.142] +synonym: "protein acyltransferase activity" EXACT [EC:2.3.1.142] +xref: EC:2.3.1.142 +xref: MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN +is_a: GO:0016416 ! O-palmitoyltransferase activity +is_a: GO:0140103 ! catalytic activity, acting on a glycoprotein + +[Term] +id: GO:0047966 +name: glycosulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate." [EC:3.1.6.3, RHEA:19145] +synonym: "glucosulfatase activity" EXACT [EC:3.1.6.3] +synonym: "glycosulphatase activity" EXACT [] +synonym: "sugar-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.3] +xref: EC:3.1.6.3 +xref: KEGG_REACTION:R00534 +xref: MetaCyc:GLYCOSULFATASE-RXN +xref: RHEA:19145 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0047967 +name: glycyrrhizinate beta-glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate." [EC:3.2.1.128, RHEA:17369] +synonym: "glycyrrhizin beta-hydrolase activity" EXACT [EC:3.2.1.128] +synonym: "glycyrrhizin hydrolase activity" EXACT [EC:3.2.1.128] +synonym: "glycyrrhizinate b-glucuronidase activity" EXACT [] +synonym: "glycyrrhizinate glucuronosylhydrolase activity" EXACT [EC:3.2.1.128] +synonym: "glycyrrhizinic acid hydrolase activity" EXACT [EC:3.2.1.128] +xref: EC:3.2.1.128 +xref: KEGG_REACTION:R03906 +xref: MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN +xref: RHEA:17369 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0047968 +name: glyoxylate dehydrogenase (acylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA." [EC:1.2.1.17, RHEA:21024] +synonym: "glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)" EXACT [EC:1.2.1.17] +xref: EC:1.2.1.17 +xref: KEGG_REACTION:R00468 +xref: MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN +xref: RHEA:21024 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047969 +name: glyoxylate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate." [EC:1.2.3.5, RHEA:14837] +synonym: "glyoxylate:oxygen oxidoreductase activity" EXACT [EC:1.2.3.5] +xref: EC:1.2.3.5 +xref: KEGG_REACTION:R00466 +xref: MetaCyc:GLYOXYLATE-OXIDASE-RXN +xref: Reactome:R-HSA-389862 "Conversion of glyoxylate to oxalate" +xref: RHEA:14837 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0047970 +name: guanidinoacetase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea." [EC:3.5.3.2, RHEA:23268] +synonym: "glycocyaminase activity" EXACT [EC:3.5.3.2] +synonym: "guanidinoacetate amidinohydrolase activity" EXACT [EC:3.5.3.2] +xref: EC:3.5.3.2 +xref: KEGG_REACTION:R00775 +xref: MetaCyc:GUANIDINOACETASE-RXN +xref: RHEA:23268 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047971 +name: guanidinobutyrase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea." [EC:3.5.3.7, RHEA:19501] +synonym: "4-guanidinobutanoate amidinohydrolase activity" EXACT [EC:3.5.3.7] +synonym: "4-guanidinobutyrate amidinobutyrase activity" EXACT [EC:3.5.3.7] +synonym: "G-base activity" EXACT [EC:3.5.3.7] +synonym: "gamma-guanidinobutyrate amidinohydrolase activity" EXACT [EC:3.5.3.7] +synonym: "gamma-guanidobutyrase activity" EXACT [EC:3.5.3.7] +synonym: "GBH" RELATED [EC:3.5.3.7] +synonym: "guanidinobutyrate ureahydrolase activity" EXACT [EC:3.5.3.7] +xref: EC:3.5.3.7 +xref: KEGG_REACTION:R01990 +xref: MetaCyc:GUANIDINOBUTYRASE-RXN +xref: RHEA:19501 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047972 +name: guanidinopropionase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea." [EC:3.5.3.17, RHEA:16029] +synonym: "3-guanidinopropanoate amidinopropionase activity" EXACT [EC:3.5.3.17] +synonym: "GPase activity" EXACT [EC:3.5.3.17] +synonym: "GPH" RELATED [EC:3.5.3.17] +xref: EC:3.5.3.17 +xref: KEGG_REACTION:R00913 +xref: MetaCyc:GUANIDINOPROPIONASE-RXN +xref: RHEA:16029 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0047973 +name: guanidinoacetate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate." [EC:2.7.3.1, RHEA:14145] +synonym: "ATP:guanidinoacetate N-phosphotransferase activity" EXACT [EC:2.7.3.1] +synonym: "glycocyamine kinase activity" EXACT [EC:2.7.3.1] +synonym: "guanidoacetate kinase activity" EXACT [] +xref: EC:2.7.3.1 +xref: KEGG_REACTION:R02575 +xref: MetaCyc:GUANIDOACETATE-KINASE-RXN +xref: RHEA:14145 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0047974 +name: guanosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanosine + H2O = xanthosine + NH3." [EC:3.5.4.15, MetaCyc:GUANOSINE-DEAMINASE-RXN] +synonym: "guanosine aminase activity" EXACT [EC:3.5.4.15] +synonym: "guanosine aminohydrolase activity" EXACT [EC:3.5.4.15] +xref: EC:3.5.4.15 +xref: MetaCyc:GUANOSINE-DEAMINASE-RXN +xref: RHEA:12861 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0047975 +name: guanosine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate." [EC:2.4.2.15, MetaCyc:GUANPHOSPHOR-RXN] +synonym: "guanosine:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.15] +synonym: "guanosine:phosphate D-ribosyltransferase activity" EXACT [EC:2.4.2.15] +xref: EC:2.4.2.15 +xref: MetaCyc:GUANPHOSPHOR-RXN +xref: RHEA:13233 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0047976 +name: hamamelose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+)." [EC:2.7.1.102, RHEA:22796] +synonym: "ATP/hamamelose 2'-phosphotransferase activity" EXACT [EC:2.7.1.102] +synonym: "ATP:D-hamamelose 2'-phosphotransferase activity" EXACT [EC:2.7.1.102] +synonym: "hamamelose kinase (phosphorylating)" EXACT [EC:2.7.1.102] +synonym: "hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)" EXACT [EC:2.7.1.102] +xref: EC:2.7.1.102 +xref: KEGG_REACTION:R03766 +xref: MetaCyc:HAMAMELOSE-KINASE-RXN +xref: RHEA:22796 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0047977 +name: hepoxilin-epoxide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate." [EC:3.3.2.7, MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN] +synonym: "(5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity" EXACT [EC:3.3.2.7] +synonym: "hepoxilin A(3) hydrolase activity" RELATED [EC:3.3.2.7] +synonym: "hepoxilin A3 hydrolase activity" EXACT [EC:3.3.2.7] +synonym: "hepoxilin epoxide hydrolase activity" EXACT [EC:3.3.2.7] +synonym: "hepoxylin hydrolase activity" RELATED [EC:3.3.2.7] +xref: EC:3.3.2.7 +xref: MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN +xref: Reactome:R-HSA-2161949 "HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH" +xref: RHEA:16665 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0047978 +name: hexadecanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH." [EC:1.1.1.164, MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN] +synonym: "hexadecanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.164] +xref: EC:1.1.1.164 +xref: MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN +xref: RHEA:22056 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047979 +name: hexose oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202." [EC:1.1.3.5, MetaCyc:HEXOSE-OXIDASE-RXN] +synonym: "D-hexose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.5] +xref: EC:1.1.3.5 +xref: MetaCyc:HEXOSE-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047980 +name: hippurate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine." [EC:3.5.1.32, RHEA:10424] +synonym: "benzoylglycine amidohydrolase activity" EXACT [EC:3.5.1.32] +synonym: "hippuricase activity" EXACT [EC:3.5.1.32] +synonym: "N-benzoylamino-acid amidohydrolase activity" EXACT [EC:3.5.1.32] +xref: EC:3.5.1.32 +xref: KEGG_REACTION:R01424 +xref: MetaCyc:HIPPURATE-HYDROLASE-RXN +xref: RHEA:10424 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0047981 +name: histidine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+)." [EC:2.3.1.33, RHEA:24596] +synonym: "acetyl-CoA:L-histidine N-acetyltransferase activity" EXACT [EC:2.3.1.33] +synonym: "acetylhistidine synthetase activity" EXACT [EC:2.3.1.33] +synonym: "histidine acetyltransferase activity" EXACT [EC:2.3.1.33] +xref: EC:2.3.1.33 +xref: KEGG_REACTION:R01160 +xref: MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:24596 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0047982 +name: homocysteine desulfhydrase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate." [EC:4.4.1.2, MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN] +synonym: "homocysteine desulfurase activity" EXACT [EC:4.4.1.2] +synonym: "L-homocysteine hydrogen-sulfide-lyase (deaminating)" EXACT [EC:4.4.1.2] +synonym: "L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.2] +xref: EC:4.4.1.2 +xref: MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN +xref: Reactome:R-HSA-1614631 "Homocysteine is degraded to oxobutanoate and H2S" +xref: RHEA:14501 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0047983 +name: homoglutathione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate." [EC:6.3.2.23, RHEA:17993] +synonym: "beta-alanine specific hGSH synthetase activity" EXACT [EC:6.3.2.23] +synonym: "gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.23] +synonym: "homoglutathione synthetase activity" EXACT [EC:6.3.2.23] +xref: EC:6.3.2.23 +xref: KEGG_REACTION:R02741 +xref: MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN +xref: RHEA:17993 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0047985 +name: hydrogen dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2 + NAD+ = H+ + NADH." [EC:1.12.1.2, MetaCyc:HYDROGEN-DEHYDROGENASE-RXN] +synonym: "bidirectional hydrogenase activity" BROAD [EC:1.12.1.2] +synonym: "H(2):NAD(+) oxidoreductase activity" EXACT [EC:1.12.1.2] +synonym: "H2:NAD+ oxidoreductase activity" EXACT [EC:1.12.1.2] +synonym: "hydrogen:NAD+ oxidoreductase activity" EXACT [EC:1.12.1.2] +synonym: "hydrogenase activity" BROAD [EC:1.12.1.2] +synonym: "NAD-linked hydrogenase activity" EXACT [EC:1.12.1.2] +xref: EC:1.12.1.2 +xref: MetaCyc:HYDROGEN-DEHYDROGENASE-RXN +xref: RHEA:24636 +is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor + +[Term] +id: GO:0047986 +name: hydrogen-sulfide S-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate." [EC:2.3.1.10, RHEA:16625] +synonym: "acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity" EXACT [EC:2.3.1.10] +synonym: "hydrogen-sulfide acetyltransferase activity" EXACT [EC:2.3.1.10] +synonym: "hydrogen-sulphide S-acetyltransferase activity" EXACT [] +xref: EC:2.3.1.10 +xref: KEGG_REACTION:R01850 +xref: MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN +xref: RHEA:16625 +is_a: GO:0016418 ! S-acetyltransferase activity + +[Term] +id: GO:0047987 +name: hydroperoxide dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O." [EC:4.2.1.92, MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN] +synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]" RELATED [EC:4.2.1.92] +synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity" EXACT [EC:4.2.1.92] +synonym: "HPI" RELATED [EC:4.2.1.92] +synonym: "hydroperoxide isomerase activity" EXACT [EC:4.2.1.92] +synonym: "linoleate hydroperoxide isomerase" RELATED [EC:4.2.1.92] +synonym: "linoleic acid hydroperoxide isomerase" RELATED [EC:4.2.1.92] +xref: EC:4.2.1.92 +xref: MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN +xref: RHEA:25075 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0047988 +name: hydroxyacid-oxoacid transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate." [EC:1.1.99.24, MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN] +synonym: "(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity" EXACT [EC:1.1.99.24] +synonym: "transhydrogenase, hydroxy acid-oxo acid" EXACT [EC:1.1.99.24] +xref: EC:1.1.99.24 +xref: MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN +xref: Reactome:R-HSA-880002 "(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate" +xref: Reactome:R-HSA-880033 "2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde" +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0047989 +name: hydroxybutyrate-dimer hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+)." [EC:3.1.1.22, RHEA:10172] +synonym: "(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity" EXACT [EC:3.1.1.22] +synonym: "D-(-)-3-hydroxybutyrate-dimer hydrolase activity" EXACT [EC:3.1.1.22] +xref: EC:3.1.1.22 +xref: KEGG_REACTION:R00048 +xref: MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN +xref: RHEA:10172 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0047990 +name: hydroxyglutamate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2)." [EC:4.1.1.16, RHEA:14073] +synonym: "3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming)" EXACT [EC:4.1.1.16] +synonym: "3-hydroxy-L-glutamate 1-carboxy-lyase activity" EXACT [EC:4.1.1.16] +xref: EC:4.1.1.16 +xref: KEGG_REACTION:R04135 +xref: MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN +xref: RHEA:14073 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047991 +name: hydroxylamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite." [RHEA:19969] +synonym: "HAO" RELATED [EC:1.7.3.6] +synonym: "hydroxylamine oxidoreductase" BROAD [EC:1.7.3.6] +synonym: "hydroxylamine:oxygen oxidoreductase activity" RELATED [EC:1.7.3.6] +xref: EC:1.7.3.6 +xref: KEGG_REACTION:R00793 +xref: MetaCyc:HAONITRO-RXN +xref: RHEA:19969 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor + +[Term] +id: GO:0047992 +name: hydroxylysine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+)." [EC:2.7.1.81, RHEA:19049] +synonym: "GTP:5-hydroxy-L-lysine O-phosphotransferase activity" EXACT [EC:2.7.1.81] +synonym: "guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity" EXACT [EC:2.7.1.81] +synonym: "hydroxylysine kinase (phosphorylating)" EXACT [EC:2.7.1.81] +xref: EC:2.7.1.81 +xref: KEGG_REACTION:R03378 +xref: MetaCyc:HYDROXYLYSINE-KINASE-RXN +xref: Reactome:R-HSA-6788611 "HYKK phosphorylates 5HLYS" +xref: RHEA:19049 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019202 ! amino acid kinase activity + +[Term] +id: GO:0047993 +name: hydroxymalonate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate." [EC:1.1.1.167, RHEA:11284] +synonym: "hydroxymalonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.167] +xref: EC:1.1.1.167 +xref: KEGG_REACTION:R02969 +xref: MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN +xref: RHEA:11284 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047994 +name: hydroxymethylglutaryl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+)." [EC:3.1.2.5, RHEA:16305] +synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity" EXACT [EC:3.1.2.5] +synonym: "3-hydroxy-3-methylglutaryl-CoA hydrolase activity" EXACT [EC:3.1.2.5] +synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity" EXACT [EC:3.1.2.5] +synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity" EXACT [EC:3.1.2.5] +synonym: "hydroxymethylglutaryl coenzyme A deacylase activity" EXACT [EC:3.1.2.5] +synonym: "hydroxymethylglutaryl coenzyme A hydrolase activity" EXACT [EC:3.1.2.5] +xref: EC:3.1.2.5 +xref: KEGG_REACTION:R02083 +xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN +xref: RHEA:16305 +is_a: GO:0016289 ! CoA hydrolase activity + +[Term] +id: GO:0047995 +name: hydroxyphenylpyruvate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH." [EC:1.1.1.237, MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN, RHEA:10780] +synonym: "4-hydroxyphenyllactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.237] +synonym: "HPRP" RELATED [EC:1.1.1.237] +xref: EC:1.1.1.237 +xref: MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN +xref: RHEA:10780 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0047996 +name: hydroxyphytanate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2)." [EC:1.1.3.27, RHEA:21680] +synonym: "L-2-hydroxyphytanate:oxygen 2-oxidoreductase" BROAD [EC:1.1.3.27] +xref: EC:1.1.3.27 +xref: KEGG_REACTION:R07151 +xref: MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN +xref: RHEA:21680 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0047997 +name: hydroxypyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde." [EC:4.1.1.40, RHEA:20561] +synonym: "hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)" EXACT [EC:4.1.1.40] +synonym: "hydroxypyruvate carboxy-lyase activity" EXACT [EC:4.1.1.40] +xref: EC:4.1.1.40 +xref: KEGG_REACTION:R01393 +xref: MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN +xref: RHEA:20561 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0047998 +name: hyoscyamine (6S)-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate." [EC:1.14.11.11, RHEA:12629] +synonym: "hyoscyamine (6S)-hydroxylase activity" EXACT [EC:1.14.11.11] +synonym: "hyoscyamine 6-beta-hydroxylase activity" EXACT [EC:1.14.11.11] +synonym: "hyoscyamine 6-hydroxylase activity" EXACT [EC:1.14.11.11] +synonym: "hyoscyamine 6beta-dioxygenase activity" EXACT [EC:1.14.11.11] +synonym: "hyoscyamine 6beta-hydroxylase activity" EXACT [EC:1.14.11.11] +synonym: "L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)" EXACT [EC:1.14.11.11] +xref: EC:1.14.11.11 +xref: KEGG_REACTION:R03812 +xref: MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN +xref: RHEA:12629 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0047999 +name: hyponitrite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH." [EC:1.7.1.5, RHEA:19337] +synonym: "hydroxylamine:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.5] +synonym: "NADH2:hyponitrite oxidoreductase activity" EXACT [EC:1.7.1.5] +synonym: "NADH:hyponitrite oxidoreductase activity" EXACT [EC:1.7.1.5] +xref: EC:1.7.1.5 +xref: KEGG_REACTION:R00023 +xref: MetaCyc:HYPONITRITE-REDUCTASE-RXN +xref: RHEA:19337 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0048000 +name: isoflavone 3'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O." [EC:1.14.14.88, MetaCyc:ISOFLAVONE-3'-HYDROXYLASE-RXN] +synonym: "formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.14.88] +synonym: "isoflavone 3'-monooxygenase activity" EXACT [EC:1.14.14.88] +xref: EC:1.14.14.88 +xref: MetaCyc:RXN-3762 +xref: RHEA:22960 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0048001 +name: erythrose-4-phosphate dehydrogenase activity +namespace: molecular_function +alt_id: GO:0033724 +def: "Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH." [EC:1.2.1.72, RHEA:12056] +synonym: "D-erythrose 4-phosphate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.72] +synonym: "E4P dehydrogenase activity" EXACT [EC:1.2.1.72] +synonym: "E4PDH" EXACT [EC:1.2.1.72] +synonym: "Epd dehydrogenase activity" EXACT [EC:1.2.1.72] +synonym: "erythrose 4-phosphate dehydrogenase activity" EXACT [EC:1.2.1.72] +synonym: "GapB" RELATED [EC:1.2.1.72] +xref: EC:1.2.1.72 +xref: KEGG_REACTION:R01825 +xref: MetaCyc:ERYTH4PDEHYDROG-RXN +xref: RHEA:12056 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0048002 +name: antigen processing and presentation of peptide antigen +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein." [GOC:add, ISBN:0781735149, PMID:15771591] +synonym: "antigen presentation, peptide antigen" EXACT [] +synonym: "peptide antigen processing and presentation" EXACT [] +is_a: GO:0019882 ! antigen processing and presentation + +[Term] +id: GO:0048003 +name: antigen processing and presentation of lipid antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family." [GOC:add, PMID:10375559, PMID:15928678, PMID:15928680] +synonym: "antigen presentation, lipid antigen" EXACT [] +synonym: "lipid antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0002475 ! antigen processing and presentation via MHC class Ib + +[Term] +id: GO:0048006 +name: antigen processing and presentation, endogenous lipid antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family." [GOC:add, PMID:10375559, PMID:15928678, PMID:15928680] +synonym: "antigen presentation, endogenous lipid antigen" EXACT [] +synonym: "endogenous lipid antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0019883 ! antigen processing and presentation of endogenous antigen +is_a: GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0048007 +name: antigen processing and presentation, exogenous lipid antigen via MHC class Ib +namespace: biological_process +def: "The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family." [GOC:add, PMID:10375559, PMID:15928678, PMID:15928680] +synonym: "antigen presentation, exogenous peptide antigen" EXACT [] +synonym: "exogenous lipid antigen processing and presentation via MHC class Ib" EXACT [] +is_a: GO:0019884 ! antigen processing and presentation of exogenous antigen +is_a: GO:0048003 ! antigen processing and presentation of lipid antigen via MHC class Ib + +[Term] +id: GO:0048008 +name: platelet-derived growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands." [GOC:ceb] +synonym: "PDGF receptor signaling pathway" EXACT [] +synonym: "PDGF receptor signalling pathway" EXACT [] +synonym: "PDGFR signaling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0048009 +name: insulin-like growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands." [GOC:ceb] +synonym: "IGF receptor signaling pathway" EXACT [] +synonym: "IGF receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0048010 +name: vascular endothelial growth factor receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, GOC:signaling, PR:000001971] +comment: In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. In contrast, the VEGFR refers to PR:000001971. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0048010 is for annotation of any pathway in which a ligand (VEGF or an alternative growth factor) binds and activates a VEGFR (PR:000001971). For annotation of signaling pathways where a VEGF binds to a cell surface receptor (VEGFR, PDGFR etc.), consider 'vascular endothelial growth factor signaling pathway ; GO:0038084'. +synonym: "VEGF receptor signaling pathway" EXACT [] +synonym: "VEGF receptor signalling pathway" EXACT [] +synonym: "VEGFR signaling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +property_value: RO:0002161 NCBITaxon_Union:0000023 + +[Term] +id: GO:0048011 +name: neurotrophin TRK receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:ceb, GOC:jc, GOC:signaling, PMID:12065629, Wikipedia:Trk_receptor] +synonym: "TrkA signaling pathway" NARROW [Wikipedia:TrkA] +synonym: "TrkB signaling pathway" NARROW [Wikipedia:TrkB] +synonym: "TrkC signaling pathway" NARROW [Wikipedia:TrkC] +synonym: "tropomyosin-receptor-kinase signaling" EXACT [Wikipedia:Trk_receptor] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +is_a: GO:0038179 ! neurotrophin signaling pathway + +[Term] +id: GO:0048012 +name: hepatocyte growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands." [GOC:ceb] +synonym: "HGF receptor signaling pathway" EXACT [] +synonym: "HGF receptor signalling pathway" EXACT [] +synonym: "Met signaling pathway" NARROW [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0048013 +name: ephrin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin." [GOC:ceb] +synonym: "Eph receptor signaling pathway" EXACT [] +synonym: "Eph receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0048014 +name: Tie signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin)." [GOC:ceb, GOC:signaling, PMID:11283723, PMID:11566266] +synonym: "angiopoietin-Tie signaling pathway" NARROW [PMID:22951441] +synonym: "angiopoietin/Tie signaling pathway" NARROW [PMID:11566266] +synonym: "Tek receptor signaling" EXACT [] +synonym: "Tie receptor signaling pathway" EXACT [GOC:ceb] +synonym: "Tie receptor signalling pathway" EXACT [] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway + +[Term] +id: GO:0048015 +name: phosphatidylinositol-mediated signaling +namespace: biological_process +def: "A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, GOC:ceb, ISBN:0198506732] +synonym: "inositol phospholipid-mediated signaling" BROAD [] +synonym: "phosphatidylinositol-mediated signal transduction" EXACT [GOC:signaling] +synonym: "phosphatidylinositol-mediated signalling" EXACT [] +synonym: "phosphoinositide-mediated signaling" EXACT [] +synonym: "phosphoinositide-mediated signalling" EXACT [] +is_a: GO:0048017 ! inositol lipid-mediated signaling + +[Term] +id: GO:0048016 +name: inositol phosphate-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6)." [GOC:bf, GOC:ceb, GOC:signaling, ISBN:0198506732, PMID:11331907] +synonym: "inositol phosphate-mediated signalling" EXACT [] +is_a: GO:0019932 ! second-messenger-mediated signaling + +[Term] +id: GO:0048017 +name: inositol lipid-mediated signaling +namespace: biological_process +def: "A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids." [GOC:bf, GOC:ceb, PMID:16088939] +synonym: "inositol lipid-mediated signal transduction" EXACT [GOC:signaling] +synonym: "inositol lipid-mediated signalling" EXACT [] +synonym: "inositol phospholipid-mediated signaling" NARROW [] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0048018 +name: receptor ligand activity +namespace: molecular_function +alt_id: GO:0071884 +def: "The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands)." [GOC:kv, GOC:molecular_function_refactoring, GOC:pdt] +subset: goslim_chembl +subset: goslim_drosophila +synonym: "receptor agonist activity" BROAD [GOC:molecular_function_refactoring] +synonym: "signaling molecule" EXACT [] +synonym: "signaling receptor ligand activity" EXACT [] +synonym: "vitamin D receptor activator activity" NARROW [] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0030546 ! signaling receptor activator activity +relationship: part_of GO:0007165 ! signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14220 xsd:anyURI +created_by: mah +creation_date: 2010-09-13T04:51:59Z + +[Term] +id: GO:0048019 +name: receptor antagonist activity +namespace: molecular_function +def: "The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor." [GOC:ceb, ISBN:0198506732] +synonym: "receptor ligand activity" BROAD [GOC:mtg_signaling] +is_a: GO:0005102 ! signaling receptor binding +is_a: GO:0030547 ! receptor inhibitor activity + +[Term] +id: GO:0048020 +name: CCR chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR chemokine receptor." [GOC:ai] +synonym: "beta chemokine receptor binding" EXACT [] +synonym: "beta chemokine receptor ligand" NARROW [] +synonym: "CCR chemokine receptor ligand" NARROW [] +is_a: GO:0042379 ! chemokine receptor binding + +[Term] +id: GO:0048021 +name: regulation of melanin biosynthetic process +namespace: biological_process +def: "Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jid] +synonym: "regulation of melanin anabolism" EXACT [] +synonym: "regulation of melanin biosynthesis" EXACT [] +synonym: "regulation of melanin formation" EXACT [] +synonym: "regulation of melanin synthesis" EXACT [] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042438 ! melanin biosynthetic process +relationship: regulates GO:0042438 ! melanin biosynthetic process + +[Term] +id: GO:0048022 +name: negative regulation of melanin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jid] +synonym: "down regulation of melanin biosynthetic process" EXACT [] +synonym: "down-regulation of melanin biosynthetic process" EXACT [] +synonym: "downregulation of melanin biosynthetic process" EXACT [] +synonym: "inhibition of melanin biosynthetic process" NARROW [] +synonym: "negative regulation of melanin anabolism" EXACT [] +synonym: "negative regulation of melanin biosynthesis" EXACT [] +synonym: "negative regulation of melanin formation" EXACT [] +synonym: "negative regulation of melanin synthesis" EXACT [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0048021 ! regulation of melanin biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042438 ! melanin biosynthetic process +relationship: negatively_regulates GO:0042438 ! melanin biosynthetic process + +[Term] +id: GO:0048023 +name: positive regulation of melanin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jid] +synonym: "activation of melanin biosynthetic process" NARROW [] +synonym: "positive regulation of melanin anabolism" EXACT [] +synonym: "positive regulation of melanin biosynthesis" EXACT [] +synonym: "positive regulation of melanin formation" EXACT [] +synonym: "positive regulation of melanin synthesis" EXACT [] +synonym: "stimulation of melanin biosynthetic process" NARROW [] +synonym: "up regulation of melanin biosynthetic process" EXACT [] +synonym: "up-regulation of melanin biosynthetic process" EXACT [] +synonym: "upregulation of melanin biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0048021 ! regulation of melanin biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042438 ! melanin biosynthetic process +relationship: positively_regulates GO:0042438 ! melanin biosynthetic process + +[Term] +id: GO:0048024 +name: regulation of mRNA splicing, via spliceosome +namespace: biological_process +alt_id: GO:0035055 +def: "Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jid] +synonym: "regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "regulation of nuclear mRNA splicing, via spliceosome" EXACT [GOC:vw] +synonym: "regulation of pre-mRNA splicing" BROAD [] +is_a: GO:0043484 ! regulation of RNA splicing +is_a: GO:0050684 ! regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000398 ! mRNA splicing, via spliceosome +relationship: regulates GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0048025 +name: negative regulation of mRNA splicing, via spliceosome +namespace: biological_process +alt_id: GO:0035056 +def: "Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jid] +synonym: "down regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "down regulation of nuclear mRNA splicing, via spliceosome" EXACT [] +synonym: "down-regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "down-regulation of nuclear mRNA splicing, via spliceosome" EXACT [] +synonym: "downregulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "downregulation of nuclear mRNA splicing, via spliceosome" EXACT [] +synonym: "inhibition of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "inhibition of nuclear mRNA splicing, via spliceosome" NARROW [] +synonym: "negative regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "negative regulation of nuclear mRNA splicing, via spliceosome" EXACT [GOC:vw] +synonym: "negative regulation of pre-mRNA splicing" BROAD [] +is_a: GO:0033119 ! negative regulation of RNA splicing +is_a: GO:0048024 ! regulation of mRNA splicing, via spliceosome +is_a: GO:0050686 ! negative regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000398 ! mRNA splicing, via spliceosome +relationship: negatively_regulates GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0048026 +name: positive regulation of mRNA splicing, via spliceosome +namespace: biological_process +alt_id: GO:0035057 +def: "Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jid] +synonym: "activation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "activation of nuclear mRNA splicing, via spliceosome" NARROW [] +synonym: "positive regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "positive regulation of nuclear mRNA splicing, via spliceosome" EXACT [GOC:vw] +synonym: "positive regulation of pre-mRNA splicing" BROAD [] +synonym: "stimulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "stimulation of nuclear mRNA splicing, via spliceosome" NARROW [] +synonym: "up regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "up regulation of nuclear mRNA splicing, via spliceosome" EXACT [] +synonym: "up-regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "up-regulation of nuclear mRNA splicing, via spliceosome" EXACT [] +synonym: "upregulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] +synonym: "upregulation of nuclear mRNA splicing, via spliceosome" EXACT [] +is_a: GO:0033120 ! positive regulation of RNA splicing +is_a: GO:0048024 ! regulation of mRNA splicing, via spliceosome +is_a: GO:0050685 ! positive regulation of mRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000398 ! mRNA splicing, via spliceosome +relationship: positively_regulates GO:0000398 ! mRNA splicing, via spliceosome + +[Term] +id: GO:0048027 +name: mRNA 5'-UTR binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule." [GOC:jid] +synonym: "mRNA 5' UTR binding" EXACT [] +is_a: GO:0003729 ! mRNA binding + +[Term] +id: GO:0048028 +name: galacturonan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins." [GOC:jid] +synonym: "polygalacturonide binding" RELATED [] +is_a: GO:0030247 ! polysaccharide binding + +[Term] +id: GO:0048029 +name: monosaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GOC:jid] +is_a: GO:0030246 ! carbohydrate binding +is_a: GO:0036094 ! small molecule binding + +[Term] +id: GO:0048030 +name: disaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any disaccharide. Disaccharides are sugars composed of two monosaccharide units." [GOC:jid] +is_a: GO:0070492 ! oligosaccharide binding + +[Term] +id: GO:0048031 +name: trisaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units." [GOC:jid] +is_a: GO:0070492 ! oligosaccharide binding + +[Term] +id: GO:0048032 +name: galacturonate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:jid] +synonym: "galacturonic acid binding" EXACT [] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0048033 +name: heme o metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle." [GOC:jid] +synonym: "haem o metabolic process" EXACT [] +synonym: "haem o metabolism" EXACT [] +synonym: "heme o metabolism" EXACT [] +is_a: GO:0042168 ! heme metabolic process + +[Term] +id: GO:0048034 +name: heme O biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle." [GOC:jid] +synonym: "haem O biosynthesis" EXACT [] +synonym: "haem O biosynthetic process" EXACT [] +synonym: "heme O anabolism" EXACT [] +synonym: "heme O biosynthesis" EXACT [] +synonym: "heme O formation" EXACT [] +synonym: "heme O synthesis" EXACT [] +is_a: GO:0006783 ! heme biosynthetic process +is_a: GO:0048033 ! heme o metabolic process + +[Term] +id: GO:0048035 +name: heme o catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle." [GOC:jid] +synonym: "haem o catabolic process" EXACT [] +synonym: "haem o catabolism" EXACT [] +synonym: "heme o breakdown" EXACT [] +synonym: "heme o catabolism" EXACT [] +synonym: "heme o degradation" EXACT [] +is_a: GO:0042167 ! heme catabolic process +is_a: GO:0048033 ! heme o metabolic process + +[Term] +id: GO:0048036 +name: central complex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli." [PMID:12490252] +synonym: "central body development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0048037 +name: cofactor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate." [ISBN:0198506732] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0048038 +name: quinone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds." [ISBN:0198506732] +is_a: GO:0048037 ! cofactor binding + +[Term] +id: GO:0048039 +name: ubiquinone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units." [GOC:jid, ISBN:0582227089] +synonym: "coenzyme Q binding" EXACT [] +synonym: "coenzyme Q6 binding" NARROW [] +is_a: GO:0048038 ! quinone binding + +[Term] +id: GO:0048040 +name: UDP-glucuronate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose." [EC:4.1.1.35, RHEA:23916] +synonym: "UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)" EXACT [EC:4.1.1.35] +synonym: "UDP-D-glucuronate carboxy-lyase activity" EXACT [EC:4.1.1.35] +synonym: "UDP-glucuronic acid decarboxylase activity" EXACT [] +synonym: "UDPglucuronate decarboxylase activity" EXACT [EC:4.1.1.35] +synonym: "uridine-diphosphoglucuronate decarboxylase activity" EXACT [EC:4.1.1.35] +xref: EC:4.1.1.35 +xref: KEGG_REACTION:R01384 +xref: MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN +xref: RHEA:23916 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0048041 +name: focal adhesion assembly +namespace: biological_process +def: "The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity." [GOC:jid, GOC:mah] +synonym: "adhesion plaque assembly" RELATED [] +synonym: "focal adhesion formation" RELATED [GOC:mah] +is_a: GO:0007044 ! cell-substrate junction assembly +relationship: part_of GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0048045 +name: trans-pentaprenyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate." [RHEA:22632] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "all-trans-hexaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.-] +synonym: "all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity" EXACT [EC:2.5.1.-] +synonym: "hexaprenyl diphosphate synthase activity" EXACT [EC:2.5.1.-] +synonym: "hexaprenyl pyrophosphate synthetase activity" EXACT [] +xref: EC:2.5.1 +xref: KEGG_REACTION:R05613 +xref: RHEA:22632 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0048046 +name: apoplast +namespace: cellular_component +def: "The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it." [GOC:jid] +xref: Wikipedia:Apoplast +is_a: GO:0005576 ! extracellular region + +[Term] +id: GO:0048047 +name: mating behavior, sex discrimination +namespace: biological_process +def: "The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner." [GOC:jid, GOC:pr, PMID:12486700] +synonym: "mating behaviour, sex discrimination" EXACT [] +is_a: GO:0007617 ! mating behavior + +[Term] +id: GO:0048048 +name: embryonic eye morphogenesis +namespace: biological_process +def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid] +is_a: GO:0048562 ! embryonic organ morphogenesis +is_a: GO:0048592 ! eye morphogenesis + +[Term] +id: GO:0048050 +name: post-embryonic eye morphogenesis +namespace: biological_process +alt_id: GO:0048051 +def: "The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight." [GOC:jid, GOC:sensu] +is_a: GO:0048563 ! post-embryonic animal organ morphogenesis +is_a: GO:0048592 ! eye morphogenesis + +[Term] +id: GO:0048052 +name: R1/R6 cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0048053 +name: R1/R6 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0048052 ! R1/R6 cell differentiation + +[Term] +id: GO:0048054 +name: R2/R5 cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0048055 +name: R2/R5 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0048054 ! R2/R5 cell differentiation + +[Term] +id: GO:0048056 +name: R3/R4 cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0001751 ! compound eye photoreceptor cell differentiation + +[Term] +id: GO:0048057 +name: R3/R4 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster." [GOC:jid] +is_a: GO:0042051 ! compound eye photoreceptor development +relationship: part_of GO:0048056 ! R3/R4 cell differentiation + +[Term] +id: GO:0048058 +name: compound eye corneal lens development +namespace: biological_process +def: "The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells." [GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048749 ! compound eye development + +[Term] +id: GO:0048060 +name: negative gravitaxis +namespace: biological_process +alt_id: GO:0048063 +def: "The directed movement of a motile cell or organism away from the source of gravity." [GOC:jid] +synonym: "negative geotactic behavior" EXACT [] +synonym: "negative geotactic behaviour" EXACT [] +synonym: "negative gravitactic behavior" EXACT [] +synonym: "negative gravitactic behaviour" EXACT [] +synonym: "negative taxis in response to gravity" EXACT [] +synonym: "negative taxis in response to gravitytaxis in response to gravitational stimulus" EXACT [] +is_a: GO:0042332 ! gravitaxis + +[Term] +id: GO:0048061 +name: positive gravitaxis +namespace: biological_process +alt_id: GO:0048064 +def: "The directed movement of a motile cell or organism towards the source of gravity." [GOC:jid] +synonym: "positive geotactic behavior" EXACT [] +synonym: "positive geotactic behaviour" EXACT [] +synonym: "positive gravitactic behavior" EXACT [] +synonym: "positive gravitactic behaviour" EXACT [] +synonym: "positive taxis in response to gravity" EXACT [] +synonym: "positive taxis in response to gravitytaxis in response to gravitational stimulus" EXACT [] +is_a: GO:0042332 ! gravitaxis + +[Term] +id: GO:0048065 +name: male courtship behavior, veined wing extension +namespace: biological_process +def: "The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster." [GOC:jid, GOC:mtg_sensu] +synonym: "male courtship behavior, wing extension" BROAD [] +synonym: "male courtship behaviour, veined wing extension" EXACT [] +synonym: "male courtship behaviour, wing extension" BROAD [] +is_a: GO:0008049 ! male courtship behavior + +[Term] +id: GO:0048066 +name: developmental pigmentation +namespace: biological_process +def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] +synonym: "pigmentation during development" RELATED [] +is_a: GO:0043473 ! pigmentation + +[Term] +id: GO:0048067 +name: cuticle pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in the cuticle of an organism." [GOC:jid] +is_a: GO:0048066 ! developmental pigmentation +relationship: part_of GO:0042335 ! cuticle development + +[Term] +id: GO:0048069 +name: eye pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in the eye of an organism." [GOC:jid] +xref: Wikipedia:Eye_color +is_a: GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0048070 +name: regulation of developmental pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] +synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048066 ! developmental pigmentation +relationship: regulates GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0048071 +name: sex-specific pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in one sex that is not observed in the other sex." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048066 ! developmental pigmentation +relationship: part_of GO:0007548 ! sex differentiation + +[Term] +id: GO:0048072 +name: compound eye pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in the compound eye." [GOC:jid] +is_a: GO:0048069 ! eye pigmentation + +[Term] +id: GO:0048073 +name: regulation of eye pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism." [GOC:jid] +is_a: GO:0048070 ! regulation of developmental pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048069 ! eye pigmentation +relationship: regulates GO:0048069 ! eye pigmentation + +[Term] +id: GO:0048074 +name: negative regulation of eye pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism." [GOC:jid] +synonym: "down regulation of eye pigmentation" EXACT [] +synonym: "down-regulation of eye pigmentation" EXACT [] +synonym: "downregulation of eye pigmentation" EXACT [] +synonym: "inhibition of eye pigmentation" NARROW [] +is_a: GO:0048073 ! regulation of eye pigmentation +is_a: GO:0048086 ! negative regulation of developmental pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048069 ! eye pigmentation +relationship: negatively_regulates GO:0048069 ! eye pigmentation + +[Term] +id: GO:0048075 +name: positive regulation of eye pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism." [GOC:jid] +synonym: "activation of eye pigmentation" NARROW [] +synonym: "stimulation of eye pigmentation" NARROW [] +synonym: "up regulation of eye pigmentation" EXACT [] +synonym: "up-regulation of eye pigmentation" EXACT [] +synonym: "upregulation of eye pigmentation" EXACT [] +is_a: GO:0048073 ! regulation of eye pigmentation +is_a: GO:0048087 ! positive regulation of developmental pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048069 ! eye pigmentation +relationship: positively_regulates GO:0048069 ! eye pigmentation + +[Term] +id: GO:0048076 +name: regulation of compound eye pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye." [GOC:jid] +is_a: GO:0048073 ! regulation of eye pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048072 ! compound eye pigmentation +relationship: regulates GO:0048072 ! compound eye pigmentation + +[Term] +id: GO:0048077 +name: negative regulation of compound eye pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye." [GOC:jid] +synonym: "down regulation of eye pigmentation" BROAD [] +synonym: "down-regulation of eye pigmentation" BROAD [] +synonym: "downregulation of eye pigmentation" BROAD [] +synonym: "inhibition of eye pigmentation" BROAD [] +synonym: "negative regulation of eye pigmentation" BROAD [] +is_a: GO:0048074 ! negative regulation of eye pigmentation +is_a: GO:0048076 ! regulation of compound eye pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048072 ! compound eye pigmentation +relationship: negatively_regulates GO:0048072 ! compound eye pigmentation + +[Term] +id: GO:0048078 +name: positive regulation of compound eye pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye." [GOC:jid] +synonym: "activation of eye pigmentation" BROAD [] +synonym: "positive regulation of eye pigmentation" BROAD [] +synonym: "stimulation of eye pigmentation" BROAD [] +synonym: "up regulation of eye pigmentation" BROAD [] +synonym: "up-regulation of eye pigmentation" BROAD [] +synonym: "upregulation of eye pigmentation" BROAD [] +is_a: GO:0048075 ! positive regulation of eye pigmentation +is_a: GO:0048076 ! regulation of compound eye pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048072 ! compound eye pigmentation +relationship: positively_regulates GO:0048072 ! compound eye pigmentation + +[Term] +id: GO:0048079 +name: regulation of cuticle pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism." [GOC:jid] +is_a: GO:0048070 ! regulation of developmental pigmentation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048067 ! cuticle pigmentation +relationship: regulates GO:0048067 ! cuticle pigmentation + +[Term] +id: GO:0048080 +name: negative regulation of cuticle pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism." [GOC:jid] +synonym: "down regulation of cuticle pigmentation" EXACT [] +synonym: "down-regulation of cuticle pigmentation" EXACT [] +synonym: "downregulation of cuticle pigmentation" EXACT [] +synonym: "inhibition of cuticle pigmentation" NARROW [] +is_a: GO:0048079 ! regulation of cuticle pigmentation +is_a: GO:0048086 ! negative regulation of developmental pigmentation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048067 ! cuticle pigmentation +relationship: negatively_regulates GO:0048067 ! cuticle pigmentation + +[Term] +id: GO:0048081 +name: positive regulation of cuticle pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism." [GOC:jid] +synonym: "activation of cuticle pigmentation" NARROW [] +synonym: "stimulation of cuticle pigmentation" NARROW [] +synonym: "up regulation of cuticle pigmentation" EXACT [] +synonym: "up-regulation of cuticle pigmentation" EXACT [] +synonym: "upregulation of cuticle pigmentation" EXACT [] +is_a: GO:0048079 ! regulation of cuticle pigmentation +is_a: GO:0048087 ! positive regulation of developmental pigmentation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048067 ! cuticle pigmentation +relationship: positively_regulates GO:0048067 ! cuticle pigmentation + +[Term] +id: GO:0048082 +name: regulation of adult chitin-containing cuticle pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism." [GOC:jid, GOC:mtg_sensu] +is_a: GO:0007564 ! regulation of chitin-based cuticle tanning +is_a: GO:0048079 ! regulation of cuticle pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048085 ! adult chitin-containing cuticle pigmentation +relationship: regulates GO:0048085 ! adult chitin-containing cuticle pigmentation + +[Term] +id: GO:0048083 +name: negative regulation of adult chitin-containing cuticle pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism." [GOC:jid, GOC:mtg_sensu] +synonym: "down regulation of adult chitin-containing cuticle pigmentation" EXACT [] +synonym: "down-regulation of adult chitin-containing cuticle pigmentation" EXACT [] +synonym: "downregulation of adult chitin-containing cuticle pigmentation" EXACT [] +synonym: "inhibition of adult chitin-containing cuticle pigmentation" NARROW [] +is_a: GO:0045800 ! negative regulation of chitin-based cuticle tanning +is_a: GO:0048080 ! negative regulation of cuticle pigmentation +is_a: GO:0048082 ! regulation of adult chitin-containing cuticle pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048085 ! adult chitin-containing cuticle pigmentation +relationship: negatively_regulates GO:0048085 ! adult chitin-containing cuticle pigmentation + +[Term] +id: GO:0048084 +name: positive regulation of adult chitin-containing cuticle pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism." [GOC:jid, GOC:mtg_sensu] +synonym: "activation of adult chitin-containing cuticle pigmentation" NARROW [] +synonym: "stimulation of adult chitin-containing cuticle pigmentation" NARROW [] +synonym: "up regulation of adult chitin-containing cuticle pigmentation" EXACT [] +synonym: "up-regulation of adult chitin-containing cuticle pigmentation" EXACT [] +synonym: "upregulation of adult chitin-containing cuticle pigmentation" EXACT [] +is_a: GO:0045801 ! positive regulation of chitin-based cuticle tanning +is_a: GO:0048081 ! positive regulation of cuticle pigmentation +is_a: GO:0048082 ! regulation of adult chitin-containing cuticle pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048085 ! adult chitin-containing cuticle pigmentation +relationship: positively_regulates GO:0048085 ! adult chitin-containing cuticle pigmentation + +[Term] +id: GO:0048085 +name: adult chitin-containing cuticle pigmentation +namespace: biological_process +alt_id: GO:0048068 +def: "Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster." [GOC:jid, GOC:mtg_sensu] +synonym: "adult cuticle pigmentation" BROAD [] +is_a: GO:0048067 ! cuticle pigmentation +relationship: part_of GO:0007593 ! chitin-based cuticle sclerotization + +[Term] +id: GO:0048086 +name: negative regulation of developmental pigmentation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] +synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] +synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] +synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] +synonym: "inhibition of pigmentation" NARROW [] +is_a: GO:0048070 ! regulation of developmental pigmentation +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048066 ! developmental pigmentation +relationship: negatively_regulates GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0048087 +name: positive regulation of developmental pigmentation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] +synonym: "activation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] +synonym: "stimulation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] +synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph] +synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] +synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, goc:tb] +is_a: GO:0048070 ! regulation of developmental pigmentation +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048066 ! developmental pigmentation +relationship: positively_regulates GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0048088 +name: regulation of male pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males." [GOC:jid] +is_a: GO:0048070 ! regulation of developmental pigmentation +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048094 ! male pigmentation +relationship: regulates GO:0048094 ! male pigmentation + +[Term] +id: GO:0048089 +name: regulation of female pigmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females." [GOC:jid] +is_a: GO:0048070 ! regulation of developmental pigmentation +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048095 ! female pigmentation +relationship: regulates GO:0048095 ! female pigmentation + +[Term] +id: GO:0048090 +name: negative regulation of female pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females." [GOC:jid] +synonym: "down regulation of female pigmentation" EXACT [] +synonym: "down-regulation of female pigmentation" EXACT [] +synonym: "downregulation of female pigmentation" EXACT [] +synonym: "inhibition of female pigmentation" NARROW [] +is_a: GO:0048086 ! negative regulation of developmental pigmentation +is_a: GO:0048089 ! regulation of female pigmentation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048095 ! female pigmentation +relationship: negatively_regulates GO:0048095 ! female pigmentation + +[Term] +id: GO:0048091 +name: positive regulation of female pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females." [GOC:jid] +synonym: "activation of female pigmentation" NARROW [] +synonym: "stimulation of female pigmentation" NARROW [] +synonym: "up regulation of female pigmentation" EXACT [] +synonym: "up-regulation of female pigmentation" EXACT [] +synonym: "upregulation of female pigmentation" EXACT [] +is_a: GO:0048087 ! positive regulation of developmental pigmentation +is_a: GO:0048089 ! regulation of female pigmentation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048095 ! female pigmentation +relationship: positively_regulates GO:0048095 ! female pigmentation + +[Term] +id: GO:0048092 +name: negative regulation of male pigmentation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males." [GOC:jid] +synonym: "down regulation of male pigmentation" EXACT [] +synonym: "down-regulation of male pigmentation" EXACT [] +synonym: "downregulation of male pigmentation" EXACT [] +synonym: "inhibition of male pigmentation" NARROW [] +is_a: GO:0048086 ! negative regulation of developmental pigmentation +is_a: GO:0048088 ! regulation of male pigmentation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048094 ! male pigmentation +relationship: negatively_regulates GO:0048094 ! male pigmentation + +[Term] +id: GO:0048093 +name: positive regulation of male pigmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males." [GOC:jid] +synonym: "activation of male pigmentation" NARROW [] +synonym: "stimulation of male pigmentation" NARROW [] +synonym: "up regulation of male pigmentation" EXACT [] +synonym: "up-regulation of male pigmentation" EXACT [] +synonym: "upregulation of male pigmentation" EXACT [] +is_a: GO:0048087 ! positive regulation of developmental pigmentation +is_a: GO:0048088 ! regulation of male pigmentation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048094 ! male pigmentation +relationship: positively_regulates GO:0048094 ! male pigmentation + +[Term] +id: GO:0048094 +name: male pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in males." [GOC:jid] +is_a: GO:0048071 ! sex-specific pigmentation +relationship: part_of GO:0046661 ! male sex differentiation + +[Term] +id: GO:0048095 +name: female pigmentation +namespace: biological_process +def: "Establishment of a pattern of pigment in females." [GOC:jid] +is_a: GO:0048071 ! sex-specific pigmentation +relationship: part_of GO:0046660 ! female sex differentiation + +[Term] +id: GO:0048096 +name: chromatin-mediated maintenance of transcription +namespace: biological_process +def: "Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable." [GOC:jid] +comment: Note that this process is the opposite of chromatin silencing. This regulation is exemplified by members of the trithorax group, which maintain the active state of homeotic gene transcription. +is_a: GO:0034401 ! chromatin organization involved in regulation of transcription +is_a: GO:0045815 ! positive regulation of gene expression, epigenetic +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated + +[Term] +id: GO:0048097 +name: long-term maintenance of gene activation +namespace: biological_process +def: "Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term." [GOC:jid] +comment: Note that this process is the opposite of gene silencing. +is_a: GO:0045815 ! positive regulation of gene expression, epigenetic + +[Term] +id: GO:0048098 +name: antennal joint development +namespace: biological_process +def: "The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments." [GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007469 ! antennal development + +[Term] +id: GO:0048099 +name: anterior/posterior lineage restriction, imaginal disc +namespace: biological_process +def: "Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment." [GOC:jid, PMID:10625531, PMID:9374402] +is_a: GO:0035161 ! imaginal disc lineage restriction +relationship: part_of GO:0007448 ! anterior/posterior pattern specification, imaginal disc + +[Term] +id: GO:0048100 +name: wing disc anterior/posterior pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing." [GOC:jid, PMID:10625531] +is_a: GO:0007448 ! anterior/posterior pattern specification, imaginal disc +is_a: GO:0035222 ! wing disc pattern formation + +[Term] +id: GO:0048101 +name: calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive." [GOC:jid] +synonym: "calcium- and calmodulin-regulated cGMP phosphodiesterase activity" RELATED [] +synonym: "calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity" EXACT [] +synonym: "calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity" EXACT [] +synonym: "calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity" EXACT [] +is_a: GO:0047555 ! 3',5'-cyclic-GMP phosphodiesterase activity + +[Term] +id: GO:0048102 +name: autophagic cell death +namespace: biological_process +def: "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells." [GOC:autophagy, GOC:mah, GOC:mtg_apoptosis, PMID:18846107, PMID:23347517] +comment: The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not. +synonym: "autophagic death" BROAD [] +synonym: "autosis" RELATED [PMID:25236395] +synonym: "programmed cell death by autophagy" BROAD [GOC:pr] +synonym: "programmed cell death by macroautophagy" EXACT [GOC:cjm] +synonym: "type II programmed cell death" RELATED [GOC:sl] +is_a: GO:0012501 ! programmed cell death +intersection_of: GO:0012501 ! programmed cell death +intersection_of: has_part GO:0016236 ! macroautophagy +relationship: has_part GO:0016236 ! macroautophagy + +[Term] +id: GO:0048103 +name: somatic stem cell division +namespace: biological_process +def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089] +synonym: "somatic stem cell renewal" EXACT [] +is_a: GO:0017145 ! stem cell division + +[Term] +id: GO:0048104 +name: establishment of body hair or bristle planar orientation +namespace: biological_process +def: "Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project." [GOC:ascb_2009, GOC:dph, GOC:jid, GOC:tb] +is_a: GO:0001736 ! establishment of planar polarity +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0048105 +name: establishment of body hair planar orientation +namespace: biological_process +def: "Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface." [GOC:ascb_2009, GOC:dph, GOC:jid, GOC:tb] +is_a: GO:0048104 ! establishment of body hair or bristle planar orientation + +[Term] +id: GO:0048106 +name: establishment of thoracic bristle planar orientation +namespace: biological_process +def: "Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction." [FBbt:00004298, FBbt:00004408, GOC:ascb_2009, GOC:dph, GOC:jid, GOC:tb] +synonym: "establishment of body bristle planar orientation" EXACT [GOC:bf] +is_a: GO:0048104 ! establishment of body hair or bristle planar orientation +relationship: part_of GO:0008407 ! chaeta morphogenesis + +[Term] +id: GO:0048107 +name: 4-amino-3-isothiazolidinone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively." [GOC:jid] +synonym: "4-amino-3-isothiazolidinone anabolism" EXACT [] +synonym: "4-amino-3-isothiazolidinone biosynthesis" EXACT [] +synonym: "4-amino-3-isothiazolidinone formation" EXACT [] +synonym: "4-amino-3-isothiazolidinone synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0048108 +name: peptide cross-linking via 4-amino-3-isothiazolidinone +namespace: biological_process +def: "The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue." [GOC:jid, GOC:jsg] +comment: Note that this is a generic parent because the identity of the second amino acid is not critical for formation of the cross-link. +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0048109 +name: peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water." [GOC:jid, PMID:12802338, PMID:12802339, RESID:AA0344] +xref: RESID:AA0344 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0048108 ! peptide cross-linking via 4-amino-3-isothiazolidinone + +[Term] +id: GO:0048132 +name: female germ-line stem cell asymmetric division +namespace: biological_process +alt_id: GO:0048141 +def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu] +synonym: "female germ-line stem cell renewal" EXACT [] +is_a: GO:0098728 ! germline stem cell asymmetric division +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0048133 +name: male germ-line stem cell asymmetric division +namespace: biological_process +def: "The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes." [GOC:jid] +synonym: "male germ-line stem cell renewal" EXACT [] +is_a: GO:0098728 ! germline stem cell asymmetric division +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0048134 +name: germ-line cyst formation +namespace: biological_process +def: "Formation of a group of interconnected cells derived from a single gonial founder cell." [GOC:jid, PMID:10370240, PMID:21681920] +synonym: "germline cyst formation" EXACT [PMID:10370240] +is_a: GO:0008283 ! cell population proliferation +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007281 ! germ cell development + +[Term] +id: GO:0048135 +name: female germ-line cyst formation +namespace: biological_process +def: "Formation of a group of interconnected cells derived from a single female gonial founder cell." [GOC:jid, PMID:10370240] +synonym: "female germline cyst formation" EXACT [PMID:10370240] +is_a: GO:0048134 ! germ-line cyst formation +relationship: part_of GO:0048477 ! oogenesis + +[Term] +id: GO:0048136 +name: male germ-line cyst formation +namespace: biological_process +def: "Formation of a group of interconnected cells derived from a single male gonial founder cell." [GOC:jid, PMID:10370240] +synonym: "male germline cyst formation" EXACT [PMID:10370240] +is_a: GO:0048134 ! germ-line cyst formation +relationship: has_part GO:0007284 ! spermatogonial cell division +relationship: has_part GO:0048137 ! spermatocyte division +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0048137 +name: spermatocyte division +namespace: biological_process +def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238] +synonym: "spermatocyte cell division" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051301 ! cell division +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0048138 +name: germ-line cyst encapsulation +namespace: biological_process +def: "Formation of a single follicular epithelium around the germ-line derived cells of a cyst." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007276 ! gamete generation +relationship: part_of GO:0016333 ! morphogenesis of follicular epithelium + +[Term] +id: GO:0048139 +name: female germ-line cyst encapsulation +namespace: biological_process +def: "Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad." [GOC:jid] +is_a: GO:0048138 ! germ-line cyst encapsulation +relationship: part_of GO:0007292 ! female gamete generation + +[Term] +id: GO:0048140 +name: male germ-line cyst encapsulation +namespace: biological_process +def: "Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad." [GOC:jid, PMID:11591336] +is_a: GO:0048138 ! germ-line cyst encapsulation +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0048142 +name: germarium-derived cystoblast division +namespace: biological_process +def: "The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster." [GOC:jid, GOC:mtg_sensu, PMID:11131529] +synonym: "germarium-derived cystoblast cell division" EXACT [] +is_a: GO:0007282 ! cystoblast division +relationship: part_of GO:0030727 ! germarium-derived female germ-line cyst formation + +[Term] +id: GO:0048143 +name: astrocyte activation +namespace: biological_process +def: "A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, PMID:10526094, PMID:10695728, PMID:12529254, PMID:12580336, PMID:9585813] +is_a: GO:0061900 ! glial cell activation +relationship: part_of GO:0014002 ! astrocyte development + +[Term] +id: GO:0048144 +name: fibroblast proliferation +namespace: biological_process +def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0048145 +name: regulation of fibroblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048144 ! fibroblast proliferation +relationship: regulates GO:0048144 ! fibroblast proliferation + +[Term] +id: GO:0048146 +name: positive regulation of fibroblast proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] +synonym: "activation of fibroblast proliferation" NARROW [] +synonym: "stimulation of fibroblast proliferation" NARROW [] +synonym: "up regulation of fibroblast proliferation" EXACT [] +synonym: "up-regulation of fibroblast proliferation" EXACT [] +synonym: "upregulation of fibroblast proliferation" EXACT [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0048145 ! regulation of fibroblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048144 ! fibroblast proliferation +relationship: positively_regulates GO:0048144 ! fibroblast proliferation + +[Term] +id: GO:0048147 +name: negative regulation of fibroblast proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] +synonym: "down regulation of fibroblast proliferation" EXACT [] +synonym: "down-regulation of fibroblast proliferation" EXACT [] +synonym: "downregulation of fibroblast proliferation" EXACT [] +synonym: "inhibition of fibroblast proliferation" NARROW [] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0048145 ! regulation of fibroblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048144 ! fibroblast proliferation +relationship: negatively_regulates GO:0048144 ! fibroblast proliferation + +[Term] +id: GO:0048148 +name: behavioral response to cocaine +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus." [GOC:jid] +synonym: "behavioural response to cocaine" EXACT [] +is_a: GO:0030534 ! adult behavior +relationship: part_of GO:0042220 ! response to cocaine + +[Term] +id: GO:0048149 +name: behavioral response to ethanol +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus." [GOC:jid] +synonym: "behavioural response to ethanol" EXACT [] +is_a: GO:0030534 ! adult behavior +relationship: part_of GO:0045471 ! response to ethanol + +[Term] +id: GO:0048150 +name: behavioral response to ether +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of an ether stimulus." [GOC:jid] +synonym: "behavioural response to ether" EXACT [] +is_a: GO:0030534 ! adult behavior +relationship: part_of GO:0045472 ! response to ether + +[Term] +id: GO:0048151 +name: obsolete hyperphosphorylation +namespace: biological_process +def: "OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both." [GOC:jid, ISBN:039751820X, PMID:12859672] +comment: This term was made obsolete because it is an unnecessary grouping term and was poorly defined. +synonym: "hyperphosphorylation" EXACT [] +is_obsolete: true +replaced_by: GO:0016310 + +[Term] +id: GO:0048152 +name: S100 beta biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jid] +synonym: "S100 beta anabolism" EXACT [] +synonym: "S100 beta biosynthesis" EXACT [] +synonym: "S100 beta formation" EXACT [] +synonym: "S100 beta synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0048153 +name: S100 alpha biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jid] +synonym: "S100 alpha anabolism" EXACT [] +synonym: "S100 alpha biosynthesis" EXACT [] +synonym: "S100 alpha formation" EXACT [] +synonym: "S100 alpha synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0048156 +name: tau protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jid] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0048158 +name: oogonium stage +namespace: biological_process +def: "The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 1" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048159 +name: primary oocyte stage +namespace: biological_process +def: "The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 2" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048160 +name: primary follicle stage +namespace: biological_process +def: "The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 3" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048161 +name: double layer follicle stage +namespace: biological_process +def: "The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 4" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048162 +name: multi-layer follicle stage +namespace: biological_process +def: "The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 5" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048163 +name: scattered antral spaces stage +namespace: biological_process +def: "The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 6" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048164 +name: distinct antral spaces stage +namespace: biological_process +def: "The stage in oogenesis when the antral spaces become distinct and the first polar body forms." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 7" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048165 +name: fused antrum stage +namespace: biological_process +def: "The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 8" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048166 +name: mature follicle stage +namespace: biological_process +def: "The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division." [GOC:jid, GOC:mtg_sensu, ISBN:0198542771] +synonym: "mammalian oogenesis stage 9" EXACT [] +is_a: GO:0022605 ! mammalian oogenesis stage + +[Term] +id: GO:0048167 +name: regulation of synaptic plasticity +namespace: biological_process +def: "A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:dph, GOC:jid, GOC:tb, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0048168 +name: regulation of neuronal synaptic plasticity +namespace: biological_process +def: "A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +is_a: GO:0048167 ! regulation of synaptic plasticity + +[Term] +id: GO:0048169 +name: regulation of long-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +is_a: GO:0048168 ! regulation of neuronal synaptic plasticity + +[Term] +id: GO:0048170 +name: positive regulation of long-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +synonym: "activation of long-term neuronal synaptic plasticity" NARROW [] +synonym: "stimulation of long-term neuronal synaptic plasticity" NARROW [] +synonym: "up regulation of long-term neuronal synaptic plasticity" EXACT [] +synonym: "up-regulation of long-term neuronal synaptic plasticity" EXACT [] +synonym: "upregulation of long-term neuronal synaptic plasticity" EXACT [] +is_a: GO:0048169 ! regulation of long-term neuronal synaptic plasticity +is_a: GO:0050769 ! positive regulation of neurogenesis + +[Term] +id: GO:0048171 +name: negative regulation of long-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +synonym: "down regulation of long-term neuronal synaptic plasticity" EXACT [] +synonym: "down-regulation of long-term neuronal synaptic plasticity" EXACT [] +synonym: "downregulation of long-term neuronal synaptic plasticity" EXACT [] +synonym: "inhibition of long-term neuronal synaptic plasticity" NARROW [] +is_a: GO:0048169 ! regulation of long-term neuronal synaptic plasticity +is_a: GO:0050768 ! negative regulation of neurogenesis + +[Term] +id: GO:0048172 +name: regulation of short-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +is_a: GO:0048168 ! regulation of neuronal synaptic plasticity + +[Term] +id: GO:0048173 +name: positive regulation of short-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +synonym: "activation of short-term neuronal synaptic plasticity" NARROW [] +synonym: "stimulation of short-term neuronal synaptic plasticity" NARROW [] +synonym: "up regulation of short-term neuronal synaptic plasticity" EXACT [] +synonym: "up-regulation of short-term neuronal synaptic plasticity" EXACT [] +synonym: "upregulation of short-term neuronal synaptic plasticity" EXACT [] +is_a: GO:0048172 ! regulation of short-term neuronal synaptic plasticity +is_a: GO:0050769 ! positive regulation of neurogenesis + +[Term] +id: GO:0048174 +name: negative regulation of short-term neuronal synaptic plasticity +namespace: biological_process +def: "A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jid, http://www.mercksource.com, PMID:11891290] +comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. +synonym: "down regulation of short-term neuronal synaptic plasticity" EXACT [] +synonym: "down-regulation of short-term neuronal synaptic plasticity" EXACT [] +synonym: "downregulation of short-term neuronal synaptic plasticity" EXACT [] +synonym: "inhibition of short-term neuronal synaptic plasticity" NARROW [] +is_a: GO:0048172 ! regulation of short-term neuronal synaptic plasticity +is_a: GO:0050768 ! negative regulation of neurogenesis + +[Term] +id: GO:0048175 +name: hepatocyte growth factor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hepacyte growth factor. Hepatocyte growth factor is a mitogen for a number of cell types and it is found in liver cells and in many other cell types, including platelets." [GOC:jid, PMID:1838014] +synonym: "hepatocyte growth factor anabolism" EXACT [] +synonym: "hepatocyte growth factor biosynthesis" EXACT [] +synonym: "hepatocyte growth factor formation" EXACT [] +synonym: "hepatocyte growth factor synthesis" EXACT [] +synonym: "HGF biosynthesis" EXACT [] +synonym: "HGF biosynthetic process" EXACT [] +synonym: "scatter factor biosynthesis" EXACT [] +synonym: "scatter factor biosynthetic process" EXACT [] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032605 ! hepatocyte growth factor production + +[Term] +id: GO:0048176 +name: regulation of hepatocyte growth factor biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jid, PMID:1838014] +synonym: "regulation of hepatocyte growth factor anabolism" EXACT [] +synonym: "regulation of hepatocyte growth factor biosynthesis" EXACT [] +synonym: "regulation of hepatocyte growth factor formation" EXACT [] +synonym: "regulation of hepatocyte growth factor synthesis" EXACT [] +synonym: "regulation of HGF biosynthesis" EXACT [] +synonym: "regulation of HGF biosynthetic process" EXACT [] +synonym: "regulation of scatter factor biosynthesis" EXACT [] +synonym: "regulation of scatter factor biosynthetic process" EXACT [] +is_a: GO:0032646 ! regulation of hepatocyte growth factor production +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048175 ! hepatocyte growth factor biosynthetic process +relationship: regulates GO:0048175 ! hepatocyte growth factor biosynthetic process + +[Term] +id: GO:0048177 +name: positive regulation of hepatocyte growth factor biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jid, PMID:1838014] +synonym: "activation of hepatocyte growth factor biosynthetic process" NARROW [] +synonym: "positive regulation of hepatocyte growth factor anabolism" EXACT [] +synonym: "positive regulation of hepatocyte growth factor biosynthesis" EXACT [] +synonym: "positive regulation of hepatocyte growth factor formation" EXACT [] +synonym: "positive regulation of hepatocyte growth factor synthesis" EXACT [] +synonym: "positive regulation of HGF biosynthesis" EXACT [] +synonym: "positive regulation of HGF biosynthetic process" EXACT [] +synonym: "positive regulation of scatter factor biosynthesis" EXACT [] +synonym: "positive regulation of scatter factor biosynthetic process" EXACT [] +synonym: "stimulation of hepatocyte growth factor biosynthetic process" NARROW [] +synonym: "up regulation of hepatocyte growth factor biosynthetic process" EXACT [] +synonym: "up-regulation of hepatocyte growth factor biosynthetic process" EXACT [] +synonym: "upregulation of hepatocyte growth factor biosynthetic process" EXACT [] +is_a: GO:0032726 ! positive regulation of hepatocyte growth factor production +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0048176 ! regulation of hepatocyte growth factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048175 ! hepatocyte growth factor biosynthetic process +relationship: positively_regulates GO:0048175 ! hepatocyte growth factor biosynthetic process + +[Term] +id: GO:0048178 +name: negative regulation of hepatocyte growth factor biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jid, PMID:1838014] +synonym: "down regulation of hepatocyte growth factor biosynthetic process" EXACT [] +synonym: "down-regulation of hepatocyte growth factor biosynthetic process" EXACT [] +synonym: "downregulation of hepatocyte growth factor biosynthetic process" EXACT [] +synonym: "inhibition of hepatocyte growth factor biosynthetic process" NARROW [] +synonym: "negative regulation of hepatocyte growth factor anabolism" EXACT [] +synonym: "negative regulation of hepatocyte growth factor biosynthesis" EXACT [] +synonym: "negative regulation of hepatocyte growth factor formation" EXACT [] +synonym: "negative regulation of hepatocyte growth factor synthesis" EXACT [] +synonym: "negative regulation of HGF biosynthesis" EXACT [] +synonym: "negative regulation of HGF biosynthetic process" EXACT [] +synonym: "negative regulation of scatter factor biosynthesis" EXACT [] +synonym: "negative regulation of scatter factor biosynthetic process" EXACT [] +is_a: GO:0032686 ! negative regulation of hepatocyte growth factor production +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0048176 ! regulation of hepatocyte growth factor biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048175 ! hepatocyte growth factor biosynthetic process +relationship: negatively_regulates GO:0048175 ! hepatocyte growth factor biosynthetic process + +[Term] +id: GO:0048179 +name: activin receptor complex +namespace: cellular_component +def: "A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed." [PMID:8307945, PMID:8622651] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0048180 +name: activin complex +namespace: cellular_component +def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit." [GOC:go_curators, http://www.mercksource.com, http://www.stedmans.com/] +comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. +subset: goslim_pir +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0048183 +name: activin AB complex +namespace: cellular_component +def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B." [GOC:go_curators, http://www.mercksource.com, http://www.stedmans.com/] +comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. +synonym: "inhibin beta-A" NARROW [] +synonym: "inhibin beta-B" NARROW [] +is_a: GO:0048180 ! activin complex + +[Term] +id: GO:0048184 +name: obsolete follistatin binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with the peptide hormone follistatin." [GOC:jid, GOC:mah] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "follistatin binding" EXACT [] +is_obsolete: true +replaced_by: GO:0017046 + +[Term] +id: GO:0048185 +name: activin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits." [GOC:jid, GOC:mah] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0048188 +name: Set1C/COMPASS complex +namespace: cellular_component +def: "A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30." [PMID:11687631, PMID:11742990, PMID:11805083, PMID:12488447, PMID:18508253, PMID:18838538] +synonym: "COMPASS complex" EXACT [GOC:vw] +synonym: "Set1/COMPASS complex" EXACT [GOC:mah] +synonym: "Set1C" EXACT [GOC:vw] +is_a: GO:0035097 ! histone methyltransferase complex + +[Term] +id: GO:0048189 +name: Lid2 complex +namespace: cellular_component +def: "A protein complex that is thought to be involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid1p, Ash2p, Ecm5p, Snt2p, and Sdc1p." [PMID:12488447] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0048190 +name: wing disc dorsal/ventral pattern formation +namespace: biological_process +def: "The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing." [GOC:jid] +synonym: "wing disc dorsal-ventral pattern formation" EXACT [GOC:mah] +synonym: "wing disc dorsoventral pattern formation" EXACT [GOC:mah] +is_a: GO:0007450 ! dorsal/ventral pattern formation, imaginal disc +is_a: GO:0035222 ! wing disc pattern formation + +[Term] +id: GO:0048191 +name: obsolete peptide stabilization activity +namespace: molecular_function +def: "OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jid] +comment: This term was made obsolete because it represents a biological process. +synonym: "peptide stabilization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0050822 + +[Term] +id: GO:0048192 +name: obsolete peptide antigen stabilization activity +namespace: molecular_function +def: "OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell." [GOC:jid] +comment: This term was made obsolete because it represents a biological process. +synonym: "peptide antigen stabilization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0050823 + +[Term] +id: GO:0048193 +name: Golgi vesicle transport +namespace: biological_process +def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233] +subset: goslim_yeast +synonym: "Golgi-derived vesicle transport" RELATED [] +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0048194 +name: Golgi vesicle budding +namespace: biological_process +def: "The evagination of the Golgi membrane, resulting in formation of a vesicle." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle budding" NARROW [] +synonym: "Golgi-derived vesicle budding" EXACT [] +is_a: GO:0006900 ! vesicle budding from membrane +relationship: occurs_in GO:0000139 ! Golgi membrane +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048195 +name: Golgi membrane priming complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "formation of dictyosome membrane priming complex" NARROW [] +synonym: "formation of Golgi membrane priming complex" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0048200 ! Golgi transport vesicle coating + +[Term] +id: GO:0048196 +name: obsolete plant extracellular matrix +namespace: cellular_component +def: "OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella." [GOC:jid, GOC:mtg_sensu, PMID:11351084, PMID:4327466] +comment: Note that this term does not have 'extracellular region ; GO:0005576' as a parent because in plants the extracellular matrix is considered part of the cell. +synonym: "middle lamella-containing extracellular matrix" RELATED [GOC:tb] +synonym: "plant extracellular matrix" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048197 +name: Golgi membrane coat protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome membrane binding by cytosolic coat proteins" NARROW [] +synonym: "dictyosome membrane bud coat oligomerisation" NARROW [] +synonym: "Golgi membrane bud coat oligomerisation" NARROW [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0048200 ! Golgi transport vesicle coating + +[Term] +id: GO:0048198 +name: Golgi vesicle bud deformation and release +namespace: biological_process +def: "The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle bud deformation" NARROW [] +synonym: "Golgi-derived vesicle bud deformation and release" EXACT [] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0048194 ! Golgi vesicle budding + +[Term] +id: GO:0048199 +name: vesicle targeting, to, from or within Golgi +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle targeting" NARROW [] +synonym: "Golgi vesicle targeting" EXACT [] +synonym: "vesicle targeting, to, from or within dictyosome" NARROW [] +is_a: GO:0006903 ! vesicle targeting +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048200 +name: Golgi transport vesicle coating +namespace: biological_process +def: "The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome transport vesicle coating" NARROW [] +is_a: GO:0006901 ! vesicle coating +relationship: part_of GO:0048194 ! Golgi vesicle budding +relationship: part_of GO:0048199 ! vesicle targeting, to, from or within Golgi + +[Term] +id: GO:0048201 +name: vesicle targeting, plasma membrane to endosome +namespace: biological_process +def: "The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "plasma membrane to endosome targeting" EXACT [] +is_a: GO:0006903 ! vesicle targeting + +[Term] +id: GO:0048202 +name: clathrin coating of Golgi vesicle +namespace: biological_process +def: "The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "clathrin coating of Golgi-derived vesicle" EXACT [] +is_a: GO:0048200 ! Golgi transport vesicle coating +is_a: GO:0048268 ! clathrin coat assembly + +[Term] +id: GO:0048203 +name: vesicle targeting, trans-Golgi to endosome +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "trans-Golgi to endosome targeting" EXACT [] +is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi +relationship: part_of GO:0006895 ! Golgi to endosome transport + +[Term] +id: GO:0048204 +name: vesicle targeting, inter-Golgi cisterna +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "inter-Golgi cisterna targeting" EXACT [] +is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi +relationship: part_of GO:0048219 ! inter-Golgi cisterna vesicle-mediated transport + +[Term] +id: GO:0048205 +name: COPI coating of Golgi vesicle +namespace: biological_process +def: "The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "COPI coating of Golgi-derived vesicle" EXACT [] +synonym: "COPI vesicle coating" RELATED [GOC:br] +is_a: GO:0048200 ! Golgi transport vesicle coating +relationship: part_of GO:0035964 ! COPI-coated vesicle budding + +[Term] +id: GO:0048206 +name: vesicle targeting, cis-Golgi to rough endoplasmic reticulum +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "cis-Golgi to rough endoplasmic reticulum targeting" EXACT [] +synonym: "cis-Golgi to rough ER targeting" EXACT [] +synonym: "vesicle targeting, cis-Golgi to rough endoplasmic reticulum" EXACT [] +synonym: "vesicle targeting, cis-Golgi to rough ER" EXACT [] +is_a: GO:0006890 ! retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi +is_a: GO:0051650 ! establishment of vesicle localization + +[Term] +id: GO:0048207 +name: vesicle targeting, rough ER to cis-Golgi +namespace: biological_process +def: "The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "rough endoplasmic reticulum to cis-Golgi targeting" EXACT [] +synonym: "rough ER to cis-Golgi targeting" EXACT [] +synonym: "vesicle targeting, rough endoplasmic reticulum to cis-Golgi" EXACT [] +is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi +relationship: part_of GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport + +[Term] +id: GO:0048208 +name: COPII vesicle coating +namespace: biological_process +def: "The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat." [GOC:ascb_2009, GOC:dph, GOC:jid, GOC:mah, GOC:tb, ISBN:0716731363, PMID:10219233] +synonym: "COPII coating of ER-derived vesicle" EXACT [GOC:tb] +synonym: "COPII vesicle coat assembly" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "COPII vesicle coat formation" EXACT [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0006901 ! vesicle coating +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0048207 ! vesicle targeting, rough ER to cis-Golgi +relationship: part_of GO:0090114 ! COPII-coated vesicle budding + +[Term] +id: GO:0048209 +name: regulation of vesicle targeting, to, from or within Golgi +namespace: biological_process +def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "regulation of Golgi vesicle targeting" EXACT [] +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi +relationship: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi + +[Term] +id: GO:0048210 +name: Golgi vesicle fusion to target membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle fusion to target membrane" NARROW [] +synonym: "Golgi-derived vesicle fusion to target membrane" EXACT [] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048211 +name: Golgi vesicle docking +namespace: biological_process +def: "The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle docking to target membrane" NARROW [] +synonym: "Golgi vesicle docking with target membrane" EXACT [] +synonym: "Golgi vesicle to membrane docking" EXACT [] +synonym: "Golgi-derived vesicle docking" EXACT [] +is_a: GO:0048278 ! vesicle docking +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048212 +name: Golgi vesicle uncoating +namespace: biological_process +def: "The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle coat depolymerization" NARROW [] +synonym: "Golgi vesicle coat depolymerization" EXACT [] +synonym: "Golgi vesicle coat protein depolymerization" EXACT [] +synonym: "Golgi-derived vesicle uncoating" EXACT [] +is_a: GO:0072319 ! vesicle uncoating +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048213 +name: Golgi vesicle prefusion complex stabilization +namespace: biological_process +def: "The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "dictyosome vesicle prefusion complex stabilisation" NARROW [] +synonym: "Golgi vesicle prefusion complex assembly" EXACT [] +synonym: "Golgi-derived vesicle prefusion complex stabilization" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048214 +name: regulation of Golgi vesicle fusion to target membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jid, ISBN:0716731363, PMID:10219233] +comment: Note that GTP-binding Rab proteins serve as regulators of vesicle targeting and fusion. +is_a: GO:0031338 ! regulation of vesicle fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048210 ! Golgi vesicle fusion to target membrane +relationship: regulates GO:0048210 ! Golgi vesicle fusion to target membrane + +[Term] +id: GO:0048215 +name: positive regulation of Golgi vesicle fusion to target membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "activation of Golgi vesicle fusion to target membrane" NARROW [] +synonym: "stimulation of Golgi vesicle fusion to target membrane" NARROW [] +synonym: "up regulation of Golgi vesicle fusion to target membrane" EXACT [] +synonym: "up-regulation of Golgi vesicle fusion to target membrane" EXACT [] +synonym: "upregulation of Golgi vesicle fusion to target membrane" EXACT [] +is_a: GO:0031340 ! positive regulation of vesicle fusion +is_a: GO:0048214 ! regulation of Golgi vesicle fusion to target membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048210 ! Golgi vesicle fusion to target membrane +relationship: positively_regulates GO:0048210 ! Golgi vesicle fusion to target membrane + +[Term] +id: GO:0048216 +name: negative regulation of Golgi vesicle fusion to target membrane +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jid, ISBN:0716731363, PMID:10219233] +synonym: "down regulation of Golgi vesicle fusion to target membrane" EXACT [] +synonym: "down-regulation of Golgi vesicle fusion to target membrane" EXACT [] +synonym: "downregulation of Golgi vesicle fusion to target membrane" EXACT [] +synonym: "inhibition of Golgi vesicle fusion to target membrane" NARROW [] +is_a: GO:0031339 ! negative regulation of vesicle fusion +is_a: GO:0048214 ! regulation of Golgi vesicle fusion to target membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048210 ! Golgi vesicle fusion to target membrane +relationship: negatively_regulates GO:0048210 ! Golgi vesicle fusion to target membrane + +[Term] +id: GO:0048217 +name: pectic matrix +namespace: cellular_component +def: "The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls." [GOC:jid, PMID:11554482] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009530 ! primary cell wall +relationship: part_of GO:0009531 ! secondary cell wall + +[Term] +id: GO:0048219 +name: inter-Golgi cisterna vesicle-mediated transport +namespace: biological_process +def: "The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] +synonym: "inter-Golgi cisterna transport" EXACT [] +is_a: GO:0006891 ! intra-Golgi vesicle-mediated transport + +[Term] +id: GO:0048222 +name: glycoprotein network +namespace: cellular_component +def: "An extracellular matrix part that consists of cross-linked glycoproteins." [GOC:mah, PMID:18508691, PMID:7048321] +synonym: "extensin" EXACT [] +xref: Wikipedia:Extensin +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009530 ! primary cell wall + +[Term] +id: GO:0048223 +name: hemicellulose network +namespace: cellular_component +def: "Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan." [DOI:10.1016/j.foodchem.2008.11.065, GOC:jid] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009530 ! primary cell wall +relationship: part_of GO:0009531 ! secondary cell wall + +[Term] +id: GO:0048224 +name: lignin network +namespace: cellular_component +def: "An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens." [GOC:jid, GOC:mah, PMID:14503002, PMID:16662709] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009531 ! secondary cell wall + +[Term] +id: GO:0048225 +name: suberin network +namespace: cellular_component +def: "An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier." [GOC:jid, GOC:mah, PMID:18440267, PMID:7706282] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009531 ! secondary cell wall + +[Term] +id: GO:0048226 +name: Casparian strip +namespace: cellular_component +def: "Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants." [GOC:jid] +xref: Wikipedia:Casparian_strip +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009531 ! secondary cell wall + +[Term] +id: GO:0048227 +name: plasma membrane to endosome transport +namespace: biological_process +def: "Transport of a vesicle from the plasma membrane to the endosome." [GOC:jid] +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0048228 +name: obsolete actin cortical patch distribution +namespace: biological_process +def: "OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells." [GOC:jid] +comment: This term was made obsolete because its definition is very similar to that of its parent term, actin cortical patch localization (GO:0051666), but somewhat unclear, and not similar enough to merge the terms. +synonym: "actin cortical patch distribution" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048229 +name: gametophyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana." [GOC:jid, PO:0009004] +synonym: "gametogenesis" BROAD [] +is_a: GO:0007275 ! multicellular organism development + +[Term] +id: GO:0048232 +name: male gamete generation +namespace: biological_process +def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] +is_a: GO:0007276 ! gamete generation + +[Term] +id: GO:0048235 +name: pollen sperm cell differentiation +namespace: biological_process +alt_id: GO:0048234 +def: "The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte." [CL:0000366, GOC:jid, GOC:mtg_sensu] +synonym: "male gamete generation" BROAD [] +synonym: "male gametophyte sperm cell differentiation" EXACT [] +synonym: "sperm cell differentiation" BROAD [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048232 ! male gamete generation +relationship: part_of GO:0055046 ! microgametogenesis + +[Term] +id: GO:0048236 +name: plant-type sporogenesis +namespace: biological_process +def: "The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes." [GOC:tb] +synonym: "plant spore formation" EXACT [] +is_a: GO:0034293 ! sexual sporulation +is_a: GO:0048869 ! cellular developmental process +is_a: GO:0051321 ! meiotic cell cycle +is_a: GO:1903046 ! meiotic cell cycle process + +[Term] +id: GO:0048237 +name: rough endoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the rough endoplasmic reticulum." [GOC:jid] +synonym: "RER lumen" EXACT [] +synonym: "rough ER lumen" EXACT [] +xref: NIF_Subcellular:sao1819509473 +is_a: GO:0005788 ! endoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0005791 ! rough endoplasmic reticulum +relationship: part_of GO:0005791 ! rough endoplasmic reticulum + +[Term] +id: GO:0048238 +name: smooth endoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the smooth endoplasmic reticulum." [GOC:jid] +synonym: "SER lumen" EXACT [] +synonym: "smooth ER lumen" EXACT [] +xref: NIF_Subcellular:sao927884761 +is_a: GO:0005788 ! endoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0005790 ! smooth endoplasmic reticulum +relationship: part_of GO:0005790 ! smooth endoplasmic reticulum + +[Term] +id: GO:0048239 +name: negative regulation of DNA recombination at telomere +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere." [GOC:jid, PMID:9635193] +synonym: "down regulation of telomeric recombination at telomere" EXACT [] +synonym: "down-regulation of telomeric recombination at telomere" EXACT [] +synonym: "downregulation of telomeric recombination at telomere" EXACT [] +synonym: "inhibition of telomeric recombination at telomere" NARROW [] +synonym: "negative regulation of telomeric recombination at telomere" EXACT [GOC:tb] +synonym: "suppression of telomeric recombination at telomere" EXACT [] +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:0072695 ! regulation of DNA recombination at telomere + +[Term] +id: GO:0048240 +name: sperm capacitation +namespace: biological_process +def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818] +comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract. +synonym: "sperm activation" RELATED [PMID:23180860] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0007286 ! spermatid development + +[Term] +id: GO:0048241 +name: epinephrine transport +namespace: biological_process +def: "The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jid] +synonym: "adrenaline transport" EXACT [] +is_a: GO:0051937 ! catecholamine transport + +[Term] +id: GO:0048242 +name: epinephrine secretion +namespace: biological_process +def: "The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system." [GOC:ef, GOC:jid] +synonym: "adrenaline secretion" EXACT [] +is_a: GO:0048241 ! epinephrine transport +is_a: GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0048243 +name: norepinephrine secretion +namespace: biological_process +def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid] +synonym: "noradrenaline secretion" EXACT [] +is_a: GO:0015874 ! norepinephrine transport +is_a: GO:0023061 ! signal release +is_a: GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0048244 +name: phytanoyl-CoA dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate." [EC:1.14.11.18, RHEA:16065] +synonym: "phytanoyl-CoA 2 oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.18] +synonym: "phytanoyl-CoA 2-hydroxylase activity" EXACT [EC:1.14.11.18] +synonym: "phytanoyl-CoA alpha-hydroxylase activity" EXACT [EC:1.14.11.18] +synonym: "phytanoyl-CoA hydroxylase activity" EXACT [EC:1.14.11.18] +synonym: "phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.11.18] +xref: EC:1.14.11.18 +xref: KEGG_REACTION:R05722 +xref: MetaCyc:1.14.11.18-RXN +xref: Reactome:R-HSA-389639 "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2" +xref: RHEA:16065 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0048245 +name: eosinophil chemotaxis +namespace: biological_process +def: "The movement of an eosinophil in response to an external stimulus." [GOC:jid, PMID:11292027, PMID:12391252] +is_a: GO:0071621 ! granulocyte chemotaxis +is_a: GO:0072677 ! eosinophil migration + +[Term] +id: GO:0048246 +name: macrophage chemotaxis +namespace: biological_process +def: "The movement of a macrophage in response to an external stimulus." [GOC:jid] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:1905517 ! macrophage migration + +[Term] +id: GO:0048247 +name: lymphocyte chemotaxis +namespace: biological_process +def: "The directed movement of a lymphocyte in response to an external stimulus." [GOC:hjd, GOC:jid, PMID:12391252] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:0072676 ! lymphocyte migration + +[Term] +id: GO:0048248 +name: CXCR3 chemokine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a the CXCR3 chemokine receptor." [GOC:jid, PMID:10556837] +is_a: GO:0045236 ! CXCR chemokine receptor binding + +[Term] +id: GO:0048249 +name: high-affinity phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:jid, PMID:8709965] +synonym: "high affinity phosphate transmembrane transporter activity" EXACT [] +is_a: GO:0015114 ! phosphate ion transmembrane transporter activity + +[Term] +id: GO:0048250 +name: iron import into the mitochondrion +namespace: biological_process +alt_id: GO:1990925 +def: "The process in which iron is transported from the cytosol, into the mitochondrial matrix." [GOC:jid, PMID:12006577] +synonym: "mitochondrial iron cation transmembrane transport" EXACT [] +synonym: "mitochondrial iron ion transmembrane transport" RELATED [] +synonym: "mitochondrial iron ion transport" RELATED [] +synonym: "mitochondrial iron transport" EXACT [] +is_a: GO:0034755 ! iron ion transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: al +creation_date: 2016-02-10T11:24:22Z + +[Term] +id: GO:0048251 +name: elastic fiber assembly +namespace: biological_process +def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674] +synonym: "elastic fibre assembly" EXACT [] +synonym: "elastin fiber assembly" EXACT [GOC:BHF] +synonym: "elastin fibre assembly" EXACT [GOC:BHF] +is_a: GO:0085029 ! extracellular matrix assembly +is_a: GO:0097435 ! supramolecular fiber organization + +[Term] +id: GO:0048252 +name: lauric acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources." [GOC:jid, PMID:15555597] +synonym: "lauric acid metabolism" EXACT [] +synonym: "n-dodecanoic acid metabolic process" EXACT [] +synonym: "n-dodecanoic acid metabolism" EXACT [] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0051791 ! medium-chain fatty acid metabolic process + +[Term] +id: GO:0048254 +name: snoRNA localization +namespace: biological_process +def: "Any process in which small nucleolar RNA is transported to, or maintained in, a specific location." [ISBN:0716731363] +synonym: "establishment and maintenance of snoRNA localization" EXACT [] +synonym: "small nucleolar RNA localization" EXACT [] +synonym: "snoRNA localisation" EXACT [GOC:mah] +is_a: GO:0006403 ! RNA localization + +[Term] +id: GO:0048255 +name: mRNA stabilization +namespace: biological_process +def: "Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules." [GOC:jid] +is_a: GO:0043488 ! regulation of mRNA stability +is_a: GO:0043489 ! RNA stabilization +is_a: GO:1902373 ! negative regulation of mRNA catabolic process + +[Term] +id: GO:0048256 +name: flap endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis." [GOC:jid] +is_a: GO:0004520 ! endodeoxyribonuclease activity + +[Term] +id: GO:0048257 +name: 3'-flap endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis." [GOC:jid, PMID:10635319] +synonym: "3' flap endonuclease activity" EXACT [] +is_a: GO:0016889 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters +is_a: GO:0048256 ! flap endonuclease activity + +[Term] +id: GO:0048258 +name: 3-ketoglucose-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose." [MetaCyc:KETOGLUCOSE-REDUCTASE-RXN] +xref: MetaCyc:KETOGLUCOSE-REDUCTASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0048259 +name: regulation of receptor-mediated endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators, GOC:tb] +synonym: "regulation of receptor mediated endocytosis" EXACT [GOC:tb] +is_a: GO:0030100 ! regulation of endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006898 ! receptor-mediated endocytosis +relationship: regulates GO:0006898 ! receptor-mediated endocytosis + +[Term] +id: GO:0048260 +name: positive regulation of receptor-mediated endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators, GOC:tb] +synonym: "activation of receptor mediated endocytosis" NARROW [] +synonym: "positive regulation of receptor mediated endocytosis" EXACT [GOC:tb] +synonym: "stimulation of receptor mediated endocytosis" NARROW [] +synonym: "up regulation of receptor mediated endocytosis" EXACT [] +synonym: "up-regulation of receptor mediated endocytosis" EXACT [] +synonym: "upregulation of receptor mediated endocytosis" EXACT [] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006898 ! receptor-mediated endocytosis +relationship: positively_regulates GO:0006898 ! receptor-mediated endocytosis + +[Term] +id: GO:0048261 +name: negative regulation of receptor-mediated endocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators] +synonym: "down regulation of receptor mediated endocytosis" EXACT [] +synonym: "down-regulation of receptor mediated endocytosis" EXACT [] +synonym: "downregulation of receptor mediated endocytosis" EXACT [] +synonym: "inhibition of receptor mediated endocytosis" NARROW [] +synonym: "negative regulation of receptor mediated endocytosis" EXACT [] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006898 ! receptor-mediated endocytosis +relationship: negatively_regulates GO:0006898 ! receptor-mediated endocytosis + +[Term] +id: GO:0048262 +name: determination of dorsal/ventral asymmetry +namespace: biological_process +def: "Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis." [GOC:jid] +synonym: "determination of adaxial/abaxial asymmetry" RELATED [GOC:dph, GOC:tb] +synonym: "determination of dorsal-ventral asymmetry" EXACT [GOC:mah] +synonym: "determination of dorsoventral asymmetry" EXACT [GOC:mah] +is_a: GO:0009855 ! determination of bilateral symmetry +relationship: part_of GO:0009953 ! dorsal/ventral pattern formation + +[Term] +id: GO:0048263 +name: determination of dorsal identity +namespace: biological_process +def: "Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:jid] +synonym: "determination of adaxial identity" RELATED [GOC:dph, GOC:tb] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0048262 ! determination of dorsal/ventral asymmetry + +[Term] +id: GO:0048264 +name: determination of ventral identity +namespace: biological_process +def: "The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:dph, GOC:isa_complete, GOC:jid] +synonym: "determination of abaxial identity" EXACT [] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0048262 ! determination of dorsal/ventral asymmetry + +[Term] +id: GO:0048265 +name: response to pain +namespace: biological_process +alt_id: GO:0048267 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli." [GOC:jid, PMID:10203867, PMID:12723742, PMID:12843304, Wikipedia:Pain] +synonym: "physiological response to pain" EXACT [] +is_a: GO:0033555 ! multicellular organismal response to stress + +[Term] +id: GO:0048266 +name: behavioral response to pain +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli." [GOC:jid] +synonym: "behavioural response to pain" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0048265 ! response to pain + +[Term] +id: GO:0048268 +name: clathrin coat assembly +namespace: biological_process +def: "The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage." [GOC:jid, PMID:11460887, PMID:11977118, PMID:9531549] +synonym: "clathrin cage assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0048269 +name: methionine adenosyltransferase complex +namespace: cellular_component +def: "A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules." [EC:2.5.1.6, GOC:jid, PMID:10644686] +synonym: "MAT complex" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0048270 +name: methionine adenosyltransferase regulator activity +namespace: molecular_function +def: "Modulates the activity of methionine adenosyltransferase." [EC:2.5.1.6, GOC:jid, PMID:10644686] +comment: See also the molecular function term 'methionine adenosyltransferase activity ; GO:0004478'. +synonym: "MAT regulator activity" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0004478 ! methionine adenosyltransferase activity + +[Term] +id: GO:0048273 +name: mitogen-activated protein kinase p38 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation." [GOC:curators, PMID:17827184] +synonym: "MAPK p38 binding" EXACT [] +is_a: GO:0051019 ! mitogen-activated protein kinase binding + +[Term] +id: GO:0048275 +name: N-terminal peptidyl-arginine acetylation +namespace: biological_process +def: "The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase." [GOC:jsg, PMID:12883043, RESID:AA0354] +xref: RESID:AA0354 +is_a: GO:0006474 ! N-terminal protein amino acid acetylation +is_a: GO:0018195 ! peptidyl-arginine modification + +[Term] +id: GO:0048277 +name: obsolete nonexocytotic vesicle docking +namespace: biological_process +def: "OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process." [GOC:jid] +comment: This term was made obsolete because it violates the principle of positivity. +synonym: "non-exocytotic vesicle docking" EXACT [] +synonym: "nonexocytotic vesicle docking" EXACT [] +is_obsolete: true +replaced_by: GO:0048278 + +[Term] +id: GO:0048278 +name: vesicle docking +namespace: biological_process +def: "The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere." [GOC:ai, GOC:jid] +synonym: "vesicle to membrane docking" EXACT [] +is_a: GO:0140056 ! organelle localization by membrane tethering +relationship: part_of GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0048279 +name: vesicle fusion with endoplasmic reticulum +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum." [GOC:jid] +synonym: "vesicle fusion with ER" EXACT [] +is_a: GO:0006906 ! vesicle fusion + +[Term] +id: GO:0048280 +name: vesicle fusion with Golgi apparatus +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0048281 +name: inflorescence morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010016 ! shoot system morphogenesis +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0010229 ! inflorescence development + +[Term] +id: GO:0048282 +name: determinate inflorescence morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems." [GOC:jid, PMID:9553044] +is_a: GO:0048281 ! inflorescence morphogenesis + +[Term] +id: GO:0048283 +name: indeterminate inflorescence morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems." [GOC:jid] +is_a: GO:0048281 ! inflorescence morphogenesis + +[Term] +id: GO:0048284 +name: organelle fusion +namespace: biological_process +def: "The creation of a single organelle from two or more organelles." [GOC:jid] +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0048285 +name: organelle fission +namespace: biological_process +def: "The creation of two or more organelles by division of one organelle." [GOC:jid] +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0048286 +name: lung alveolus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways." [GOC:mtg_lung, PMID:9751757] +synonym: "alveolarization" EXACT [PMID:17911382] +synonym: "alveologenesis" EXACT [GOC:17911382] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0048288 +name: nuclear membrane fusion involved in karyogamy +namespace: biological_process +def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid] +synonym: "nuclear membrane fusion during karyogamy" RELATED [GOC:dph, GOC:tb] +is_a: GO:0000740 ! nuclear membrane fusion +intersection_of: GO:0000740 ! nuclear membrane fusion +intersection_of: part_of GO:0000741 ! karyogamy +relationship: part_of GO:0000741 ! karyogamy + +[Term] +id: GO:0048289 +name: isotype switching to IgE isotypes +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus." [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655] +synonym: "class switch recombination to IgE isotypes" EXACT [] +synonym: "class switching to IgE isotypes" EXACT [] +synonym: "isotype switch recombination to IgE isotypes" EXACT [] +is_a: GO:0045190 ! isotype switching + +[Term] +id: GO:0048290 +name: isotype switching to IgA isotypes +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus." [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655] +synonym: "class switching to IgA isotypes" EXACT [] +synonym: "isotype switch recombination to IgA isotypes" EXACT [] +is_a: GO:0045190 ! isotype switching + +[Term] +id: GO:0048291 +name: isotype switching to IgG isotypes +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus." [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655] +synonym: "class switching to IgG isotypes" EXACT [] +synonym: "isotype switch recombination to IgG isotypes" EXACT [] +is_a: GO:0045190 ! isotype switching + +[Term] +id: GO:0048292 +name: isotype switching to IgD isotypes +namespace: biological_process +def: "The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus." [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655] +comment: Note that this term is to be used only for gene products involved in the expression of IgD through recombinational switching into the vestigial switch region at the 5' end of the IgD gene segment, rather than gene products involved in the expression of IgD through alternative splicing mechanisms. +synonym: "class switching to IgD isotypes" EXACT [] +synonym: "isotype switch recombination to IgD isotypes" EXACT [] +is_a: GO:0045190 ! isotype switching + +[Term] +id: GO:0048293 +name: regulation of isotype switching to IgE isotypes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jid] +synonym: "regulation of class switch recombination to IgE isotypes" EXACT [] +synonym: "regulation of class switching to IgE isotypes" EXACT [] +synonym: "regulation of isotype switch recombination to IgE isotypes" EXACT [] +is_a: GO:0045191 ! regulation of isotype switching +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048289 ! isotype switching to IgE isotypes +relationship: regulates GO:0048289 ! isotype switching to IgE isotypes + +[Term] +id: GO:0048294 +name: negative regulation of isotype switching to IgE isotypes +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jid] +synonym: "down regulation of isotype switching to IgE isotypes" EXACT [] +synonym: "down-regulation of isotype switching to IgE isotypes" EXACT [] +synonym: "downregulation of isotype switching to IgE isotypes" EXACT [] +synonym: "inhibition of isotype switching to IgE isotypes" NARROW [] +synonym: "negative regulation of class switch recombination to IgE isotypes" EXACT [] +synonym: "negative regulation of class switching to IgE isotypes" EXACT [] +synonym: "negative regulation of isotype switch recombination to IgE isotypes" EXACT [] +is_a: GO:0045829 ! negative regulation of isotype switching +is_a: GO:0048293 ! regulation of isotype switching to IgE isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048289 ! isotype switching to IgE isotypes +relationship: negatively_regulates GO:0048289 ! isotype switching to IgE isotypes + +[Term] +id: GO:0048295 +name: positive regulation of isotype switching to IgE isotypes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jid] +synonym: "activation of isotype switching to IgE isotypes" NARROW [] +synonym: "positive regulation of class switch recombination to IgE isotypes" EXACT [] +synonym: "positive regulation of class switching to IgE isotypes" EXACT [] +synonym: "positive regulation of isotype switch recombination to IgE isotypes" EXACT [] +synonym: "stimulation of isotype switching to IgE isotypes" NARROW [] +synonym: "up regulation of isotype switching to IgE isotypes" EXACT [] +synonym: "up-regulation of isotype switching to IgE isotypes" EXACT [] +synonym: "upregulation of isotype switching to IgE isotypes" EXACT [] +is_a: GO:0045830 ! positive regulation of isotype switching +is_a: GO:0048293 ! regulation of isotype switching to IgE isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048289 ! isotype switching to IgE isotypes +relationship: positively_regulates GO:0048289 ! isotype switching to IgE isotypes + +[Term] +id: GO:0048296 +name: regulation of isotype switching to IgA isotypes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jid] +synonym: "regulation of class switch recombination to IgA isotypes" EXACT [] +synonym: "regulation of class switching to IgA isotypes" EXACT [] +synonym: "regulation of isotype switch recombination to IgA isotypes" EXACT [] +is_a: GO:0045191 ! regulation of isotype switching +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048290 ! isotype switching to IgA isotypes +relationship: regulates GO:0048290 ! isotype switching to IgA isotypes + +[Term] +id: GO:0048297 +name: negative regulation of isotype switching to IgA isotypes +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jid] +synonym: "down regulation of isotype switching to IgA isotypes" EXACT [] +synonym: "down-regulation of isotype switching to IgA isotypes" EXACT [] +synonym: "downregulation of isotype switching to IgA isotypes" EXACT [] +synonym: "inhibition of isotype switching to IgA isotypes" NARROW [] +synonym: "negative regulation of class switch recombination to IgA isotypes" EXACT [] +synonym: "negative regulation of class switching to IgA isotypes" EXACT [] +synonym: "negative regulation of isotype switch recombination to IgA isotypes" EXACT [] +is_a: GO:0045829 ! negative regulation of isotype switching +is_a: GO:0048296 ! regulation of isotype switching to IgA isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048290 ! isotype switching to IgA isotypes +relationship: negatively_regulates GO:0048290 ! isotype switching to IgA isotypes + +[Term] +id: GO:0048298 +name: positive regulation of isotype switching to IgA isotypes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jid] +synonym: "activation of isotype switching to IgA isotypes" NARROW [] +synonym: "positive regulation of class switch recombination to IgA isotypes" EXACT [] +synonym: "positive regulation of class switching to IgA isotypes" EXACT [] +synonym: "positive regulation of isotype switch recombination to IgA isotypes" EXACT [] +synonym: "stimulation of isotype switching to IgA isotypes" NARROW [] +synonym: "up regulation of isotype switching to IgA isotypes" EXACT [] +synonym: "up-regulation of isotype switching to IgA isotypes" EXACT [] +synonym: "upregulation of isotype switching to IgA isotypes" EXACT [] +is_a: GO:0045830 ! positive regulation of isotype switching +is_a: GO:0048296 ! regulation of isotype switching to IgA isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048290 ! isotype switching to IgA isotypes +relationship: positively_regulates GO:0048290 ! isotype switching to IgA isotypes + +[Term] +id: GO:0048299 +name: regulation of isotype switching to IgD isotypes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jid] +synonym: "regulation of class switch recombination to IgD isotypes" EXACT [] +synonym: "regulation of class switching to IgD isotypes" EXACT [] +synonym: "regulation of isotype switch recombination to IgD isotypes" EXACT [] +is_a: GO:0045191 ! regulation of isotype switching +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048292 ! isotype switching to IgD isotypes +relationship: regulates GO:0048292 ! isotype switching to IgD isotypes + +[Term] +id: GO:0048300 +name: negative regulation of isotype switching to IgD isotypes +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jid] +synonym: "down regulation of isotype switching to IgD isotypes" EXACT [] +synonym: "down-regulation of isotype switching to IgD isotypes" EXACT [] +synonym: "downregulation of isotype switching to IgD isotypes" EXACT [] +synonym: "inhibition of isotype switching to IgD isotypes" NARROW [] +synonym: "negative regulation of class switch recombination to IgD isotypes" EXACT [] +synonym: "negative regulation of class switching to IgD isotypes" EXACT [] +synonym: "negative regulation of isotype switch recombination to IgD isotypes" EXACT [] +is_a: GO:0045829 ! negative regulation of isotype switching +is_a: GO:0048299 ! regulation of isotype switching to IgD isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048292 ! isotype switching to IgD isotypes +relationship: negatively_regulates GO:0048292 ! isotype switching to IgD isotypes + +[Term] +id: GO:0048301 +name: positive regulation of isotype switching to IgD isotypes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jid] +synonym: "activation of isotype switching to IgD isotypes" NARROW [] +synonym: "positive regulation of class switch recombination to IgD isotypes" EXACT [] +synonym: "positive regulation of class switching to IgD isotypes" EXACT [] +synonym: "positive regulation of isotype switch recombination to IgD isotypes" EXACT [] +synonym: "stimulation of isotype switching to IgD isotypes" NARROW [] +synonym: "up regulation of isotype switching to IgD isotypes" EXACT [] +synonym: "up-regulation of isotype switching to IgD isotypes" EXACT [] +synonym: "upregulation of isotype switching to IgD isotypes" EXACT [] +is_a: GO:0045830 ! positive regulation of isotype switching +is_a: GO:0048299 ! regulation of isotype switching to IgD isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048292 ! isotype switching to IgD isotypes +relationship: positively_regulates GO:0048292 ! isotype switching to IgD isotypes + +[Term] +id: GO:0048302 +name: regulation of isotype switching to IgG isotypes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jid] +synonym: "regulation of class switch recombination to IgG isotypes" EXACT [] +synonym: "regulation of class switching to IgG isotypes" EXACT [] +synonym: "regulation of isotype switch recombination to IgG isotypes" EXACT [] +is_a: GO:0045191 ! regulation of isotype switching +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048291 ! isotype switching to IgG isotypes +relationship: regulates GO:0048291 ! isotype switching to IgG isotypes + +[Term] +id: GO:0048303 +name: negative regulation of isotype switching to IgG isotypes +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jid] +synonym: "down regulation of isotype switching to IgG isotypes" EXACT [] +synonym: "down-regulation of isotype switching to IgG isotypes" EXACT [] +synonym: "downregulation of isotype switching to IgG isotypes" EXACT [] +synonym: "inhibition of isotype switching to IgG isotypes" NARROW [] +synonym: "negative regulation of class switch recombination to IgG isotypes" EXACT [] +synonym: "negative regulation of class switching to IgG isotypes" EXACT [] +synonym: "negative regulation of isotype switch recombination to IgG isotypes" EXACT [] +is_a: GO:0045829 ! negative regulation of isotype switching +is_a: GO:0048302 ! regulation of isotype switching to IgG isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048291 ! isotype switching to IgG isotypes +relationship: negatively_regulates GO:0048291 ! isotype switching to IgG isotypes + +[Term] +id: GO:0048304 +name: positive regulation of isotype switching to IgG isotypes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jid] +synonym: "activation of isotype switching to IgG isotypes" NARROW [] +synonym: "positive regulation of class switch recombination to IgG isotypes" EXACT [] +synonym: "positive regulation of class switching to IgG isotypes" EXACT [] +synonym: "positive regulation of isotype switch recombination to IgG isotypes" EXACT [] +synonym: "stimulation of isotype switching to IgG isotypes" NARROW [] +synonym: "up regulation of isotype switching to IgG isotypes" EXACT [] +synonym: "up-regulation of isotype switching to IgG isotypes" EXACT [] +synonym: "upregulation of isotype switching to IgG isotypes" EXACT [] +is_a: GO:0045830 ! positive regulation of isotype switching +is_a: GO:0048302 ! regulation of isotype switching to IgG isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048291 ! isotype switching to IgG isotypes +relationship: positively_regulates GO:0048291 ! isotype switching to IgG isotypes + +[Term] +id: GO:0048305 +name: immunoglobulin secretion +namespace: biological_process +def: "The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin." [GOC:add, ISBN:0781735149, PMID:9185563] +synonym: "antibody secretion" EXACT [] +is_a: GO:0009306 ! protein secretion +relationship: part_of GO:0002377 ! immunoglobulin production + +[Term] +id: GO:0048306 +name: calcium-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium." [GOC:jid, PMID:10485905] +is_a: GO:0005515 ! protein binding +intersection_of: GO:0005515 ! protein binding +intersection_of: has_part GO:0005509 ! calcium ion binding +relationship: has_part GO:0005509 ! calcium ion binding + +[Term] +id: GO:0048307 +name: ferredoxin-nitrite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+." [EC:1.7.7.1, GOC:jid] +synonym: "ammonia:ferredoxin oxidoreductase activity" EXACT [EC:1.7.7.1] +xref: EC:1.7.7.1 +xref: MetaCyc:FERREDOXIN--NITRITE-REDUCTASE-RXN +is_a: GO:0016664 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor +is_a: GO:0098809 ! nitrite reductase activity + +[Term] +id: GO:0048308 +name: organelle inheritance +namespace: biological_process +def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid] +subset: goslim_pir +subset: goslim_yeast +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0048309 +name: endoplasmic reticulum inheritance +namespace: biological_process +def: "The partitioning of endoplasmic reticulum between daughter cells at cell division." [GOC:jid] +synonym: "ER inheritance" EXACT [] +is_a: GO:0007029 ! endoplasmic reticulum organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0048310 +name: nucleus inheritance +namespace: biological_process +def: "The partitioning of nuclei between daughter cells at cell division." [GOC:jid] +synonym: "cell nucleus inheritance" EXACT [] +is_a: GO:0006997 ! nucleus organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0048311 +name: mitochondrion distribution +namespace: biological_process +def: "Any process that establishes the spatial arrangement of mitochondria between and within cells." [GOC:jid] +synonym: "distribution of mitochondria" EXACT [] +synonym: "mitochondrial distribution" EXACT [] +synonym: "positioning of mitochondria" RELATED [] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0051646 ! mitochondrion localization + +[Term] +id: GO:0048312 +name: intracellular distribution of mitochondria +namespace: biological_process +def: "Any process that establishes the spatial arrangement of mitochondria within the cell." [GOC:jid] +synonym: "mitochondria positioning within cell" EXACT [] +synonym: "mitochondrion positioning within cell" EXACT [] +is_a: GO:0048311 ! mitochondrion distribution + +[Term] +id: GO:0048313 +name: Golgi inheritance +namespace: biological_process +def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069] +synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "Golgi partitioning" EXACT [] +is_a: GO:0007030 ! Golgi organization +is_a: GO:0048308 ! organelle inheritance + +[Term] +id: GO:0048314 +name: embryo sac morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants." [GOC:jid, GOC:mtg_plant, http://www.bio.uu.nl] +synonym: "female gametophyte morphogenesis" EXACT [] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0048315 +name: conidium formation +namespace: biological_process +def: "The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus." [GOC:di, ISBN:0963117211, PMID:2524423, PMID:9529886] +synonym: "conidia biosynthesis" RELATED [] +synonym: "conidia formation" EXACT [] +is_a: GO:0030436 ! asexual sporulation +relationship: part_of GO:0061794 ! conidium development + +[Term] +id: GO:0048316 +name: seed development +namespace: biological_process +def: "The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves." [GOC:jid, PO:0009010] +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0010154 ! fruit development + +[Term] +id: GO:0048317 +name: seed morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the seed are generated and organized." [GOC:go_curators] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0048318 +name: axial mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh] +is_a: GO:0007498 ! mesoderm development + +[Term] +id: GO:0048319 +name: axial mesoderm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators] +is_a: GO:0048332 ! mesoderm morphogenesis +relationship: part_of GO:0048318 ! axial mesoderm development + +[Term] +id: GO:0048320 +name: axial mesoderm formation +namespace: biological_process +def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] +is_a: GO:0001707 ! mesoderm formation +relationship: part_of GO:0048319 ! axial mesoderm morphogenesis + +[Term] +id: GO:0048321 +name: axial mesodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell." [GOC:dgh] +synonym: "axial mesoderm cell differentiation" EXACT [] +is_a: GO:0048333 ! mesodermal cell differentiation +relationship: part_of GO:0048320 ! axial mesoderm formation + +[Term] +id: GO:0048322 +name: axial mesodermal cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become an axial mesoderm cell." [GOC:dgh] +synonym: "axial mesoderm cell fate commitment" EXACT [] +is_a: GO:0001710 ! mesodermal cell fate commitment +relationship: part_of GO:0048321 ! axial mesodermal cell differentiation + +[Term] +id: GO:0048323 +name: axial mesodermal cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:dgh] +synonym: "axial mesoderm cell fate determination" EXACT [] +is_a: GO:0007500 ! mesodermal cell fate determination +relationship: part_of GO:0048322 ! axial mesodermal cell fate commitment + +[Term] +id: GO:0048324 +name: regulation of axial mesodermal cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048323 ! axial mesodermal cell fate determination +relationship: regulates GO:0048323 ! axial mesodermal cell fate determination + +[Term] +id: GO:0048325 +name: negative regulation of axial mesodermal cell fate determination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] +synonym: "down regulation of axial mesodermal cell fate determination" EXACT [] +synonym: "down-regulation of axial mesodermal cell fate determination" EXACT [] +synonym: "downregulation of axial mesodermal cell fate determination" EXACT [] +synonym: "inhibition of axial mesodermal cell fate determination" NARROW [] +is_a: GO:0048324 ! regulation of axial mesodermal cell fate determination +is_a: GO:0048335 ! negative regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048323 ! axial mesodermal cell fate determination +relationship: negatively_regulates GO:0048323 ! axial mesodermal cell fate determination + +[Term] +id: GO:0048326 +name: positive regulation of axial mesodermal cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] +synonym: "activation of axial mesodermal cell fate determination" NARROW [] +synonym: "stimulation of axial mesodermal cell fate determination" NARROW [] +synonym: "up regulation of axial mesodermal cell fate determination" EXACT [] +synonym: "up-regulation of axial mesodermal cell fate determination" EXACT [] +synonym: "upregulation of axial mesodermal cell fate determination" EXACT [] +is_a: GO:0048324 ! regulation of axial mesodermal cell fate determination +is_a: GO:0048336 ! positive regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048323 ! axial mesodermal cell fate determination +relationship: positively_regulates GO:0048323 ! axial mesodermal cell fate determination + +[Term] +id: GO:0048327 +name: axial mesodermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dgh] +synonym: "axial mesoderm cell fate specification" EXACT [] +is_a: GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0048322 ! axial mesodermal cell fate commitment + +[Term] +id: GO:0048328 +name: regulation of axial mesodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048327 ! axial mesodermal cell fate specification +relationship: regulates GO:0048327 ! axial mesodermal cell fate specification + +[Term] +id: GO:0048329 +name: negative regulation of axial mesodermal cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] +synonym: "down regulation of axial mesodermal cell fate specification" EXACT [] +synonym: "down-regulation of axial mesodermal cell fate specification" EXACT [] +synonym: "downregulation of axial mesodermal cell fate specification" EXACT [] +synonym: "inhibition of axial mesodermal cell fate specification" NARROW [] +is_a: GO:0042662 ! negative regulation of mesodermal cell fate specification +is_a: GO:0048328 ! regulation of axial mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048327 ! axial mesodermal cell fate specification +relationship: negatively_regulates GO:0048327 ! axial mesodermal cell fate specification + +[Term] +id: GO:0048330 +name: positive regulation of axial mesodermal cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] +synonym: "activation of axial mesodermal cell fate specification" NARROW [] +synonym: "stimulation of axial mesodermal cell fate specification" NARROW [] +synonym: "up regulation of axial mesodermal cell fate specification" EXACT [] +synonym: "up-regulation of axial mesodermal cell fate specification" EXACT [] +synonym: "upregulation of axial mesodermal cell fate specification" EXACT [] +is_a: GO:0048328 ! regulation of axial mesodermal cell fate specification +is_a: GO:0048337 ! positive regulation of mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048327 ! axial mesodermal cell fate specification +relationship: positively_regulates GO:0048327 ! axial mesodermal cell fate specification + +[Term] +id: GO:0048331 +name: axial mesoderm structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh] +synonym: "axial mesoderm structural organisation" EXACT [] +is_a: GO:0048338 ! mesoderm structural organization +relationship: part_of GO:0048319 ! axial mesoderm morphogenesis + +[Term] +id: GO:0048332 +name: mesoderm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0007498 ! mesoderm development + +[Term] +id: GO:0048333 +name: mesodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh] +synonym: "mesoderm cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0001707 ! mesoderm formation + +[Term] +id: GO:0048334 +name: regulation of mesodermal cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] +is_a: GO:1905770 ! regulation of mesodermal cell differentiation +is_a: GO:1905933 ! regulation of cell fate determination +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007500 ! mesodermal cell fate determination +relationship: regulates GO:0007500 ! mesodermal cell fate determination + +[Term] +id: GO:0048335 +name: negative regulation of mesodermal cell fate determination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] +synonym: "down regulation of mesodermal cell fate determination" EXACT [] +synonym: "down-regulation of mesodermal cell fate determination" EXACT [] +synonym: "downregulation of mesodermal cell fate determination" EXACT [] +synonym: "inhibition of mesodermal cell fate determination" NARROW [] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +is_a: GO:1905771 ! negative regulation of mesodermal cell differentiation +is_a: GO:1905934 ! negative regulation of cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007500 ! mesodermal cell fate determination +relationship: negatively_regulates GO:0007500 ! mesodermal cell fate determination + +[Term] +id: GO:0048336 +name: positive regulation of mesodermal cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] +synonym: "activation of mesodermal cell fate determination" NARROW [] +synonym: "stimulation of mesodermal cell fate determination" NARROW [] +synonym: "up regulation of mesodermal cell fate determination" EXACT [] +synonym: "up-regulation of mesodermal cell fate determination" EXACT [] +synonym: "upregulation of mesodermal cell fate determination" EXACT [] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +is_a: GO:1905772 ! positive regulation of mesodermal cell differentiation +is_a: GO:1905935 ! positive regulation of cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007500 ! mesodermal cell fate determination +relationship: positively_regulates GO:0007500 ! mesodermal cell fate determination + +[Term] +id: GO:0048337 +name: positive regulation of mesodermal cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification." [GOC:dgh] +synonym: "activation of mesodermal cell fate specification" NARROW [] +synonym: "stimulation of mesodermal cell fate specification" NARROW [] +synonym: "up regulation of mesodermal cell fate specification" EXACT [] +synonym: "up-regulation of mesodermal cell fate specification" EXACT [] +synonym: "upregulation of mesodermal cell fate specification" EXACT [] +is_a: GO:0042660 ! positive regulation of cell fate specification +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +is_a: GO:1905772 ! positive regulation of mesodermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007501 ! mesodermal cell fate specification +relationship: positively_regulates GO:0007501 ! mesodermal cell fate specification + +[Term] +id: GO:0048338 +name: mesoderm structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh] +synonym: "mesoderm structural organisation" EXACT [] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0048332 ! mesoderm morphogenesis + +[Term] +id: GO:0048339 +name: paraxial mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh] +is_a: GO:0007498 ! mesoderm development +is_a: GO:0060485 ! mesenchyme development + +[Term] +id: GO:0048340 +name: paraxial mesoderm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators] +is_a: GO:0048332 ! mesoderm morphogenesis +is_a: GO:0072132 ! mesenchyme morphogenesis +relationship: part_of GO:0048339 ! paraxial mesoderm development + +[Term] +id: GO:0048341 +name: paraxial mesoderm formation +namespace: biological_process +def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] +is_a: GO:0001707 ! mesoderm formation +relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis + +[Term] +id: GO:0048342 +name: paraxial mesodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell." [GOC:dgh] +is_a: GO:0048333 ! mesodermal cell differentiation +relationship: part_of GO:0048341 ! paraxial mesoderm formation + +[Term] +id: GO:0048343 +name: paraxial mesodermal cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become a paraxial mesoderm cell." [GOC:dgh] +is_a: GO:0001710 ! mesodermal cell fate commitment +relationship: part_of GO:0048342 ! paraxial mesodermal cell differentiation + +[Term] +id: GO:0048344 +name: paraxial mesodermal cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:dgh] +is_a: GO:0007500 ! mesodermal cell fate determination +relationship: part_of GO:0048343 ! paraxial mesodermal cell fate commitment + +[Term] +id: GO:0048345 +name: regulation of paraxial mesodermal cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048344 ! paraxial mesodermal cell fate determination +relationship: regulates GO:0048344 ! paraxial mesodermal cell fate determination + +[Term] +id: GO:0048346 +name: positive regulation of paraxial mesodermal cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] +synonym: "activation of paraxial mesodermal cell fate determination" NARROW [] +synonym: "stimulation of paraxial mesodermal cell fate determination" NARROW [] +synonym: "up regulation of paraxial mesodermal cell fate determination" EXACT [] +synonym: "up-regulation of paraxial mesodermal cell fate determination" EXACT [] +synonym: "upregulation of paraxial mesodermal cell fate determination" EXACT [] +is_a: GO:0048336 ! positive regulation of mesodermal cell fate determination +is_a: GO:0048345 ! regulation of paraxial mesodermal cell fate determination +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048344 ! paraxial mesodermal cell fate determination +relationship: positively_regulates GO:0048344 ! paraxial mesodermal cell fate determination + +[Term] +id: GO:0048347 +name: negative regulation of paraxial mesodermal cell fate determination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] +synonym: "down regulation of paraxial mesodermal cell fate determination" EXACT [] +synonym: "down-regulation of paraxial mesodermal cell fate determination" EXACT [] +synonym: "downregulation of paraxial mesodermal cell fate determination" EXACT [] +synonym: "inhibition of paraxial mesodermal cell fate determination" NARROW [] +is_a: GO:0048335 ! negative regulation of mesodermal cell fate determination +is_a: GO:0048345 ! regulation of paraxial mesodermal cell fate determination +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048344 ! paraxial mesodermal cell fate determination +relationship: negatively_regulates GO:0048344 ! paraxial mesodermal cell fate determination + +[Term] +id: GO:0048348 +name: paraxial mesodermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dgh] +is_a: GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0048343 ! paraxial mesodermal cell fate commitment + +[Term] +id: GO:0048349 +name: regulation of paraxial mesodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048348 ! paraxial mesodermal cell fate specification +relationship: regulates GO:0048348 ! paraxial mesodermal cell fate specification + +[Term] +id: GO:0048350 +name: positive regulation of paraxial mesodermal cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] +synonym: "activation of paraxial mesodermal cell fate specification" NARROW [] +synonym: "stimulation of paraxial mesodermal cell fate specification" NARROW [] +synonym: "up regulation of paraxial mesodermal cell fate specification" EXACT [] +synonym: "up-regulation of paraxial mesodermal cell fate specification" EXACT [] +synonym: "upregulation of paraxial mesodermal cell fate specification" EXACT [] +is_a: GO:0048337 ! positive regulation of mesodermal cell fate specification +is_a: GO:0048349 ! regulation of paraxial mesodermal cell fate specification +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048348 ! paraxial mesodermal cell fate specification +relationship: positively_regulates GO:0048348 ! paraxial mesodermal cell fate specification + +[Term] +id: GO:0048351 +name: negative regulation of paraxial mesodermal cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] +synonym: "down regulation of paraxial mesodermal cell fate specification" EXACT [] +synonym: "down-regulation of paraxial mesodermal cell fate specification" EXACT [] +synonym: "downregulation of paraxial mesodermal cell fate specification" EXACT [] +synonym: "inhibition of paraxial mesodermal cell fate specification" NARROW [] +is_a: GO:0042662 ! negative regulation of mesodermal cell fate specification +is_a: GO:0048349 ! regulation of paraxial mesodermal cell fate specification +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048348 ! paraxial mesodermal cell fate specification +relationship: negatively_regulates GO:0048348 ! paraxial mesodermal cell fate specification + +[Term] +id: GO:0048352 +name: paraxial mesoderm structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh] +synonym: "paraxial mesoderm structural organisation" EXACT [] +is_a: GO:0048338 ! mesoderm structural organization +relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis + +[Term] +id: GO:0048353 +name: primary endosperm nucleus +namespace: cellular_component +def: "Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac." [ISBN:0471245208] +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0048354 +name: mucilage biosynthetic process involved in seed coat development +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development." [GOC:dph, GOC:jid, GOC:tb] +synonym: "mucilage anabolism during seed coat development" EXACT [] +synonym: "mucilage biosynthetic process during seed coat development" RELATED [GOC:dph, GOC:tb] +synonym: "mucilage formation during seed coat development" EXACT [] +synonym: "mucilage synthesis during seed coat development" EXACT [] +is_a: GO:0010192 ! mucilage biosynthetic process +is_a: GO:0048359 ! mucilage metabolic process involved in seed coat development +intersection_of: GO:0010192 ! mucilage biosynthetic process +intersection_of: part_of GO:0010214 ! seed coat development + +[Term] +id: GO:0048355 +name: root cap mucilage biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth." [GOC:jid] +synonym: "root cap mucilage anabolism" EXACT [] +synonym: "root cap mucilage biosynthesis" EXACT [] +synonym: "root cap mucilage formation" EXACT [] +synonym: "root cap mucilage synthesis" EXACT [] +is_a: GO:0010192 ! mucilage biosynthetic process +relationship: part_of GO:0048360 ! root cap mucilage metabolic process + +[Term] +id: GO:0048356 +name: root epithelial mucilage biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth." [GOC:jid] +synonym: "root epithelial mucilage anabolism" EXACT [] +synonym: "root epithelial mucilage biosynthesis" EXACT [] +synonym: "root epithelial mucilage formation" EXACT [] +synonym: "root epithelial mucilage synthesis" EXACT [] +is_a: GO:0010192 ! mucilage biosynthetic process +relationship: part_of GO:0048361 ! root epithelial mucilage metabolic process + +[Term] +id: GO:0048357 +name: pedicel mucilage biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem." [GOC:jid] +synonym: "pedicel mucilage anabolism" EXACT [] +synonym: "pedicel mucilage biosynthesis" EXACT [] +synonym: "pedicel mucilage formation" EXACT [] +synonym: "pedicel mucilage synthesis" EXACT [] +is_a: GO:0010192 ! mucilage biosynthetic process +relationship: part_of GO:0048362 ! pedicel mucilage metabolic process + +[Term] +id: GO:0048358 +name: mucilage pectin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the pectin component of mucilage." [GOC:jid] +synonym: "mucilage pectin anabolism" EXACT [] +synonym: "mucilage pectin biosynthesis" EXACT [] +synonym: "mucilage pectin formation" EXACT [] +synonym: "mucilage pectin synthesis" EXACT [] +is_a: GO:0045489 ! pectin biosynthetic process +is_a: GO:0048363 ! mucilage pectin metabolic process +relationship: part_of GO:0010192 ! mucilage biosynthetic process + +[Term] +id: GO:0048359 +name: mucilage metabolic process involved in seed coat development +namespace: biological_process +def: "The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development." [GOC:dph, GOC:jid, GOC:tb] +synonym: "mucilage metabolic process during seed coat development" RELATED [GOC:dph, GOC:tb] +synonym: "mucilage metabolism during seed coat development" EXACT [] +is_a: GO:0010191 ! mucilage metabolic process +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0010191 ! mucilage metabolic process +intersection_of: part_of GO:0010214 ! seed coat development +relationship: part_of GO:0010214 ! seed coat development + +[Term] +id: GO:0048360 +name: root cap mucilage metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth." [GOC:jid] +synonym: "root cap mucilage metabolism" EXACT [] +is_a: GO:0010191 ! mucilage metabolic process + +[Term] +id: GO:0048361 +name: root epithelial mucilage metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth." [GOC:jid] +synonym: "root epithelial mucilage metabolism" EXACT [] +is_a: GO:0010191 ! mucilage metabolic process + +[Term] +id: GO:0048362 +name: pedicel mucilage metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mucilage that occur in the flower stem." [GOC:jid] +synonym: "pedicel mucilage metabolism" EXACT [] +is_a: GO:0010191 ! mucilage metabolic process + +[Term] +id: GO:0048363 +name: mucilage pectin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the pectin component of mucilage." [GOC:jid] +synonym: "mucilage pectin metabolism" EXACT [] +is_a: GO:0045488 ! pectin metabolic process +relationship: part_of GO:0010191 ! mucilage metabolic process + +[Term] +id: GO:0048364 +name: root development +namespace: biological_process +def: "The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo." [GOC:jid, PO:0009005] +is_a: GO:0099402 ! plant organ development +relationship: part_of GO:0022622 ! root system development + +[Term] +id: GO:0048365 +name: Rac GTPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases." [GOC:ebc, PMID:11702775] +is_a: GO:0017048 ! Rho GTPase binding + +[Term] +id: GO:0048366 +name: leaf development +namespace: biological_process +def: "The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048827 ! phyllome development + +[Term] +id: GO:0048367 +name: shoot system development +namespace: biological_process +alt_id: GO:0022621 +def: "The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure." [GOC:go_curators] +synonym: "shoot development" EXACT [] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0048368 +name: lateral mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators] +synonym: "lateral plate mesoderm development" EXACT [] +is_a: GO:0007498 ! mesoderm development +is_a: GO:0060485 ! mesenchyme development + +[Term] +id: GO:0048369 +name: lateral mesoderm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators] +synonym: "lateral plate mesoderm morphogenesis" EXACT [] +is_a: GO:0048332 ! mesoderm morphogenesis +is_a: GO:0072132 ! mesenchyme morphogenesis +relationship: part_of GO:0048368 ! lateral mesoderm development + +[Term] +id: GO:0048370 +name: lateral mesoderm formation +namespace: biological_process +def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid] +synonym: "lateral plate mesoderm biosynthesis" EXACT [] +synonym: "lateral plate mesoderm formation" EXACT [] +is_a: GO:0001707 ! mesoderm formation +relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis + +[Term] +id: GO:0048371 +name: lateral mesodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell." [GOC:jid] +synonym: "lateral mesoderm cell differentiation" EXACT [] +synonym: "lateral plate mesoderm cell differentiation" EXACT [] +synonym: "lateral plate mesodermal cell differentiation" EXACT [] +is_a: GO:0048333 ! mesodermal cell differentiation +relationship: part_of GO:0048370 ! lateral mesoderm formation + +[Term] +id: GO:0048372 +name: lateral mesodermal cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become a lateral mesoderm cell." [GOC:jid] +synonym: "lateral mesoderm cell fate commitment" EXACT [] +synonym: "lateral plate mesoderm cell fate commitment" EXACT [] +synonym: "lateral plate mesodermal cell fate commitment" EXACT [] +is_a: GO:0001710 ! mesodermal cell fate commitment +relationship: part_of GO:0048371 ! lateral mesodermal cell differentiation + +[Term] +id: GO:0048373 +name: lateral mesodermal cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:jid] +synonym: "lateral mesoderm cell fate determination" EXACT [] +synonym: "lateral plate mesoderm cell fate determination" EXACT [] +synonym: "lateral plate mesodermal cell fate determination" EXACT [] +is_a: GO:0007500 ! mesodermal cell fate determination +relationship: part_of GO:0048372 ! lateral mesodermal cell fate commitment + +[Term] +id: GO:0048374 +name: regulation of lateral mesodermal cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jid] +synonym: "regulation of lateral mesoderm cell fate determination" EXACT [] +synonym: "regulation of lateral plate mesoderm cell fate determination" EXACT [] +synonym: "regulation of lateral plate mesodermal cell fate determination" EXACT [] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048373 ! lateral mesodermal cell fate determination +relationship: regulates GO:0048373 ! lateral mesodermal cell fate determination + +[Term] +id: GO:0048375 +name: negative regulation of lateral mesodermal cell fate determination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jid] +synonym: "down regulation of lateral mesodermal cell fate determination" EXACT [] +synonym: "down-regulation of lateral mesodermal cell fate determination" EXACT [] +synonym: "downregulation of lateral mesodermal cell fate determination" EXACT [] +synonym: "inhibition of lateral mesodermal cell fate determination" NARROW [] +synonym: "negative regulation of lateral plate mesodermal cell fate determination" EXACT [] +is_a: GO:0048335 ! negative regulation of mesodermal cell fate determination +is_a: GO:0048374 ! regulation of lateral mesodermal cell fate determination +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048373 ! lateral mesodermal cell fate determination +relationship: negatively_regulates GO:0048373 ! lateral mesodermal cell fate determination + +[Term] +id: GO:0048376 +name: positive regulation of lateral mesodermal cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jid] +synonym: "activation of lateral mesodermal cell fate determination" NARROW [] +synonym: "positive regulation of lateral plate mesodermal cell fate determination" EXACT [] +synonym: "stimulation of lateral mesodermal cell fate determination" NARROW [] +synonym: "up regulation of lateral mesodermal cell fate determination" EXACT [] +synonym: "up-regulation of lateral mesodermal cell fate determination" EXACT [] +synonym: "upregulation of lateral mesodermal cell fate determination" EXACT [] +is_a: GO:0048336 ! positive regulation of mesodermal cell fate determination +is_a: GO:0048374 ! regulation of lateral mesodermal cell fate determination +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048373 ! lateral mesodermal cell fate determination +relationship: positively_regulates GO:0048373 ! lateral mesodermal cell fate determination + +[Term] +id: GO:0048377 +name: lateral mesodermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:jid] +synonym: "lateral mesoderm cell fate specification" EXACT [] +synonym: "lateral plate mesoderm cell fate specification" EXACT [] +synonym: "lateral plate mesodermal cell fate specification" EXACT [] +is_a: GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0048372 ! lateral mesodermal cell fate commitment + +[Term] +id: GO:0048378 +name: regulation of lateral mesodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jid] +synonym: "regulation of lateral plate mesodermal cell fate specification" EXACT [] +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048377 ! lateral mesodermal cell fate specification +relationship: regulates GO:0048377 ! lateral mesodermal cell fate specification + +[Term] +id: GO:0048379 +name: positive regulation of lateral mesodermal cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jid] +synonym: "activation of lateral mesodermal cell fate specification" NARROW [] +synonym: "positive regulation of lateral plate mesodermal cell fate specification" EXACT [] +synonym: "stimulation of lateral mesodermal cell fate specification" NARROW [] +synonym: "up regulation of lateral mesodermal cell fate specification" EXACT [] +synonym: "up-regulation of lateral mesodermal cell fate specification" EXACT [] +synonym: "upregulation of lateral mesodermal cell fate specification" EXACT [] +is_a: GO:0048337 ! positive regulation of mesodermal cell fate specification +is_a: GO:0048378 ! regulation of lateral mesodermal cell fate specification +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048377 ! lateral mesodermal cell fate specification +relationship: positively_regulates GO:0048377 ! lateral mesodermal cell fate specification + +[Term] +id: GO:0048380 +name: negative regulation of lateral mesodermal cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jid] +synonym: "down regulation of lateral mesodermal cell fate specification" EXACT [] +synonym: "down-regulation of lateral mesodermal cell fate specification" EXACT [] +synonym: "downregulation of lateral mesodermal cell fate specification" EXACT [] +synonym: "inhibition of lateral mesodermal cell fate specification" NARROW [] +synonym: "negative regulation of lateral plate mesodermal cell fate specification" EXACT [] +is_a: GO:0042662 ! negative regulation of mesodermal cell fate specification +is_a: GO:0048378 ! regulation of lateral mesodermal cell fate specification +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048377 ! lateral mesodermal cell fate specification +relationship: negatively_regulates GO:0048377 ! lateral mesodermal cell fate specification + +[Term] +id: GO:0048381 +name: lateral mesoderm structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "lateral mesoderm structural organisation" EXACT [] +synonym: "lateral plate mesoderm structural organization" EXACT [] +is_a: GO:0048338 ! mesoderm structural organization +relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis + +[Term] +id: GO:0048382 +name: mesendoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues." [GOC:jid] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007492 ! endoderm development +relationship: part_of GO:0007498 ! mesoderm development + +[Term] +id: GO:0048383 +name: mesectoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues." [GOC:jid] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0007398 ! ectoderm development +relationship: part_of GO:0007498 ! mesoderm development + +[Term] +id: GO:0048384 +name: retinoic acid receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands." [GOC:dgh] +synonym: "RAR signaling pathway" EXACT [] +synonym: "retinoic acid receptor signalling pathway" EXACT [] +is_a: GO:0030522 ! intracellular receptor signaling pathway + +[Term] +id: GO:0048385 +name: regulation of retinoic acid receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] +synonym: "regulation of RAR signaling pathway" EXACT [] +synonym: "regulation of retinoic acid receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048384 ! retinoic acid receptor signaling pathway +relationship: regulates GO:0048384 ! retinoic acid receptor signaling pathway + +[Term] +id: GO:0048386 +name: positive regulation of retinoic acid receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] +synonym: "activation of retinoic acid receptor signaling pathway" NARROW [] +synonym: "positive regulation of RAR signaling pathway" EXACT [] +synonym: "positive regulation of retinoic acid receptor signalling pathway" EXACT [] +synonym: "stimulation of retinoic acid receptor signaling pathway" NARROW [] +synonym: "up regulation of retinoic acid receptor signaling pathway" EXACT [] +synonym: "up-regulation of retinoic acid receptor signaling pathway" EXACT [] +synonym: "upregulation of retinoic acid receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0048385 ! regulation of retinoic acid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048384 ! retinoic acid receptor signaling pathway +relationship: positively_regulates GO:0048384 ! retinoic acid receptor signaling pathway + +[Term] +id: GO:0048387 +name: negative regulation of retinoic acid receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] +synonym: "down regulation of retinoic acid receptor signaling pathway" EXACT [] +synonym: "down-regulation of retinoic acid receptor signaling pathway" EXACT [] +synonym: "downregulation of retinoic acid receptor signaling pathway" EXACT [] +synonym: "inhibition of retinoic acid receptor signaling pathway" NARROW [] +synonym: "negative regulation of RAR signaling pathway" EXACT [] +synonym: "negative regulation of RAR signalling pathway" EXACT [] +synonym: "negative regulation of retinoic acid receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0048385 ! regulation of retinoic acid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048384 ! retinoic acid receptor signaling pathway +relationship: negatively_regulates GO:0048384 ! retinoic acid receptor signaling pathway + +[Term] +id: GO:0048388 +name: endosomal lumen acidification +namespace: biological_process +def: "Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion." [GOC:jid] +is_a: GO:0051452 ! intracellular pH reduction +relationship: part_of GO:0007032 ! endosome organization + +[Term] +id: GO:0048389 +name: intermediate mesoderm development +namespace: biological_process +def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh] +is_a: GO:0007498 ! mesoderm development + +[Term] +id: GO:0048390 +name: intermediate mesoderm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators] +is_a: GO:0048332 ! mesoderm morphogenesis +relationship: part_of GO:0048389 ! intermediate mesoderm development + +[Term] +id: GO:0048391 +name: intermediate mesoderm formation +namespace: biological_process +def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] +is_a: GO:0001707 ! mesoderm formation +relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis + +[Term] +id: GO:0048392 +name: intermediate mesodermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell." [GOC:dgh] +synonym: "intermediate mesoderm cell differentiation" EXACT [] +is_a: GO:0048333 ! mesodermal cell differentiation +relationship: part_of GO:0048391 ! intermediate mesoderm formation + +[Term] +id: GO:0048393 +name: intermediate mesodermal cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell." [GOC:dgh] +synonym: "intermediate mesoderm cell fate commitment" EXACT [] +is_a: GO:0001710 ! mesodermal cell fate commitment +relationship: part_of GO:0048392 ! intermediate mesodermal cell differentiation + +[Term] +id: GO:0048394 +name: intermediate mesodermal cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:dgh] +synonym: "intermediate mesoderm cell fate determination" EXACT [] +is_a: GO:0007500 ! mesodermal cell fate determination +relationship: part_of GO:0048393 ! intermediate mesodermal cell fate commitment + +[Term] +id: GO:0048395 +name: regulation of intermediate mesodermal cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] +is_a: GO:0048334 ! regulation of mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048394 ! intermediate mesodermal cell fate determination +relationship: regulates GO:0048394 ! intermediate mesodermal cell fate determination + +[Term] +id: GO:0048396 +name: negative regulation of intermediate mesodermal cell fate determination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] +synonym: "down regulation of intermediate mesodermal cell fate determination" EXACT [] +synonym: "down-regulation of intermediate mesodermal cell fate determination" EXACT [] +synonym: "downregulation of intermediate mesodermal cell fate determination" EXACT [] +synonym: "inhibition of intermediate mesodermal cell fate determination" NARROW [] +is_a: GO:0048335 ! negative regulation of mesodermal cell fate determination +is_a: GO:0048395 ! regulation of intermediate mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048394 ! intermediate mesodermal cell fate determination +relationship: negatively_regulates GO:0048394 ! intermediate mesodermal cell fate determination + +[Term] +id: GO:0048397 +name: positive regulation of intermediate mesodermal cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] +synonym: "activation of intermediate mesodermal cell fate determination" NARROW [] +synonym: "stimulation of intermediate mesodermal cell fate determination" NARROW [] +synonym: "up regulation of intermediate mesodermal cell fate determination" EXACT [] +synonym: "up-regulation of intermediate mesodermal cell fate determination" EXACT [] +synonym: "upregulation of intermediate mesodermal cell fate determination" EXACT [] +is_a: GO:0048336 ! positive regulation of mesodermal cell fate determination +is_a: GO:0048395 ! regulation of intermediate mesodermal cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048394 ! intermediate mesodermal cell fate determination +relationship: positively_regulates GO:0048394 ! intermediate mesodermal cell fate determination + +[Term] +id: GO:0048398 +name: intermediate mesodermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dgh] +synonym: "intermediate mesoderm cell fate specification" EXACT [] +is_a: GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0048393 ! intermediate mesodermal cell fate commitment + +[Term] +id: GO:0048399 +name: regulation of intermediate mesodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] +is_a: GO:0042661 ! regulation of mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048398 ! intermediate mesodermal cell fate specification +relationship: regulates GO:0048398 ! intermediate mesodermal cell fate specification + +[Term] +id: GO:0048400 +name: positive regulation of intermediate mesodermal cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] +synonym: "activation of intermediate mesodermal cell fate specification" NARROW [] +synonym: "stimulation of intermediate mesodermal cell fate specification" NARROW [] +synonym: "up regulation of intermediate mesodermal cell fate specification" EXACT [] +synonym: "up-regulation of intermediate mesodermal cell fate specification" EXACT [] +synonym: "upregulation of intermediate mesodermal cell fate specification" EXACT [] +is_a: GO:0048337 ! positive regulation of mesodermal cell fate specification +is_a: GO:0048399 ! regulation of intermediate mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048398 ! intermediate mesodermal cell fate specification +relationship: positively_regulates GO:0048398 ! intermediate mesodermal cell fate specification + +[Term] +id: GO:0048401 +name: negative regulation of intermediate mesodermal cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] +synonym: "down regulation of intermediate mesodermal cell fate specification" EXACT [] +synonym: "down-regulation of intermediate mesodermal cell fate specification" EXACT [] +synonym: "downregulation of intermediate mesodermal cell fate specification" EXACT [] +synonym: "inhibition of intermediate mesodermal cell fate specification" NARROW [] +is_a: GO:0042662 ! negative regulation of mesodermal cell fate specification +is_a: GO:0048399 ! regulation of intermediate mesodermal cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048398 ! intermediate mesodermal cell fate specification +relationship: negatively_regulates GO:0048398 ! intermediate mesodermal cell fate specification + +[Term] +id: GO:0048402 +name: intermediate mesoderm structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure." [GOC:dgh] +synonym: "intermediate mesoderm structural organisation" EXACT [] +is_a: GO:0048338 ! mesoderm structural organization +relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis + +[Term] +id: GO:0048403 +name: brain-derived neurotrophic factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with brain-derived neurotrophic factor." [GOC:dgh] +synonym: "BDNF binding" EXACT [] +synonym: "neurotrophin TRKB receptor activity" RELATED [] +is_a: GO:0043121 ! neurotrophin binding + +[Term] +id: GO:0048406 +name: nerve growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with nerve growth factor (NGF)." [GOC:dgh] +synonym: "beta-nerve growth factor binding" EXACT [PR:000011194] +synonym: "neurotrophin TRKA receptor activity" RELATED [] +synonym: "NGF binding" EXACT [PR:000011194] +is_a: GO:0043121 ! neurotrophin binding + +[Term] +id: GO:0048407 +name: platelet-derived growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with platelet-derived growth factor." [GOC:dgh] +synonym: "PDGF binding" EXACT [] +is_a: GO:0019838 ! growth factor binding + +[Term] +id: GO:0048408 +name: epidermal growth factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with epidermal growth factor." [GOC:dgh] +synonym: "EGF binding" EXACT [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0048437 +name: floral organ development +namespace: biological_process +alt_id: GO:0048433 +def: "The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure." [GOC:go_curators, GOC:PO_curators, PO:0025395] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0099402 ! plant organ development +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0048438 +name: floral whorl development +namespace: biological_process +alt_id: GO:0048413 +def: "The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant." [GOC:dph, GOC:go_curators, GOC:PO_curators, GOC:tb, PO:0025023] +comment: Consider instead annotating to one of the more specific child terms, or to 'floral organ development ; GO:0048438' or one of its child terms. +synonym: "collective phyllome structure development" BROAD [GOC:PO_curators, PO:0025023] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0048439 +name: flower morphogenesis +namespace: biological_process +alt_id: GO:0048411 +def: "The process in which the anatomical structures of the flower are generated and organized." [GOC:go_curators] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010016 ! shoot system morphogenesis +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0048440 +name: carpel development +namespace: biological_process +alt_id: GO:0048429 +def: "The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style." [GOC:go_curators] +is_a: GO:0048437 ! floral organ development +is_a: GO:0048827 ! phyllome development +relationship: part_of GO:0048467 ! gynoecium development + +[Term] +id: GO:0048441 +name: petal development +namespace: biological_process +alt_id: GO:0048417 +def: "The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048437 ! floral organ development +is_a: GO:0048827 ! phyllome development +relationship: part_of GO:0048465 ! corolla development + +[Term] +id: GO:0048442 +name: sepal development +namespace: biological_process +alt_id: GO:0048421 +def: "The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048437 ! floral organ development +is_a: GO:0048827 ! phyllome development +relationship: part_of GO:0048464 ! flower calyx development + +[Term] +id: GO:0048443 +name: stamen development +namespace: biological_process +alt_id: GO:0048425 +def: "The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048437 ! floral organ development +is_a: GO:0048827 ! phyllome development +relationship: part_of GO:0048466 ! androecium development + +[Term] +id: GO:0048444 +name: floral organ morphogenesis +namespace: biological_process +alt_id: GO:0048434 +def: "The process in which the anatomical structures of the floral organ are generated and organized." [GOC:go_curators, GOC:PO_curators, PO:0025395] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090697 ! post-embryonic plant organ morphogenesis +relationship: part_of GO:0048437 ! floral organ development + +[Term] +id: GO:0048445 +name: carpel morphogenesis +namespace: biological_process +alt_id: GO:0048430 +def: "The process in which the anatomical structures of the carpel are generated and organized." [GOC:go_curators] +is_a: GO:0048444 ! floral organ morphogenesis +relationship: part_of GO:0048440 ! carpel development + +[Term] +id: GO:0048446 +name: petal morphogenesis +namespace: biological_process +alt_id: GO:0048418 +def: "The process in which the anatomical structures of the petal are generated and organized." [GOC:go_curators] +is_a: GO:0048444 ! floral organ morphogenesis +relationship: part_of GO:0048441 ! petal development + +[Term] +id: GO:0048447 +name: sepal morphogenesis +namespace: biological_process +alt_id: GO:0048422 +def: "The process in which the anatomical structures of the sepal are generated and organized." [GOC:go_curators] +is_a: GO:0048444 ! floral organ morphogenesis +relationship: part_of GO:0048442 ! sepal development + +[Term] +id: GO:0048448 +name: stamen morphogenesis +namespace: biological_process +alt_id: GO:0048426 +def: "The process in which the anatomical structures of the stamen are generated and organized." [GOC:go_curators] +is_a: GO:0048444 ! floral organ morphogenesis +relationship: part_of GO:0048443 ! stamen development + +[Term] +id: GO:0048449 +name: floral organ formation +namespace: biological_process +alt_id: GO:0048436 +def: "The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid, GOC:PO_curators, PO:0025395] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:1905393 ! plant organ formation +relationship: part_of GO:0048444 ! floral organ morphogenesis + +[Term] +id: GO:0048450 +name: floral organ structural organization +namespace: biological_process +alt_id: GO:0048435 +def: "The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid, GOC:PO_curators, PO:0025395] +synonym: "floral organ structural organisation" EXACT [] +is_a: GO:0048444 ! floral organ morphogenesis +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0048461 ! flower structural organization + +[Term] +id: GO:0048451 +name: petal formation +namespace: biological_process +alt_id: GO:0048419 +def: "The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid] +is_a: GO:0048449 ! floral organ formation +relationship: part_of GO:0048446 ! petal morphogenesis + +[Term] +id: GO:0048452 +name: petal structural organization +namespace: biological_process +alt_id: GO:0048420 +def: "The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "petal structural organisation" EXACT [] +is_a: GO:0048450 ! floral organ structural organization +relationship: part_of GO:0048446 ! petal morphogenesis + +[Term] +id: GO:0048453 +name: sepal formation +namespace: biological_process +alt_id: GO:0048423 +def: "The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid] +is_a: GO:0048449 ! floral organ formation +relationship: part_of GO:0048447 ! sepal morphogenesis + +[Term] +id: GO:0048454 +name: sepal structural organization +namespace: biological_process +alt_id: GO:0048424 +def: "The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "sepal structural organisation" EXACT [] +is_a: GO:0048450 ! floral organ structural organization +relationship: part_of GO:0048447 ! sepal morphogenesis + +[Term] +id: GO:0048455 +name: stamen formation +namespace: biological_process +alt_id: GO:0048427 +def: "The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid] +is_a: GO:0048449 ! floral organ formation +relationship: part_of GO:0048448 ! stamen morphogenesis + +[Term] +id: GO:0048456 +name: stamen structural organization +namespace: biological_process +alt_id: GO:0048428 +def: "The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "stamen structural organisation" EXACT [] +is_a: GO:0048450 ! floral organ structural organization +relationship: part_of GO:0048448 ! stamen morphogenesis + +[Term] +id: GO:0048457 +name: floral whorl morphogenesis +namespace: biological_process +alt_id: GO:0048414 +def: "The process in which the anatomical structures of the floral whorl are generated and organized." [GOC:go_curators, GOC:PO_curators, PO:0025023] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0048438 ! floral whorl development +relationship: part_of GO:0048439 ! flower morphogenesis + +[Term] +id: GO:0048458 +name: floral whorl formation +namespace: biological_process +alt_id: GO:0048415 +def: "The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid, GOC:PO_curators, PO:0025023] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048457 ! floral whorl morphogenesis + +[Term] +id: GO:0048459 +name: floral whorl structural organization +namespace: biological_process +alt_id: GO:0048416 +def: "The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid, GOC:PO_curators, PO:0025023] +synonym: "floral whorl structural organisation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0048457 ! floral whorl morphogenesis +relationship: part_of GO:0048461 ! flower structural organization + +[Term] +id: GO:0048460 +name: flower formation +namespace: biological_process +alt_id: GO:0048410 +def: "The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048439 ! flower morphogenesis + +[Term] +id: GO:0048461 +name: flower structural organization +namespace: biological_process +alt_id: GO:0048412 +def: "The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "flower structural organisation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0048439 ! flower morphogenesis + +[Term] +id: GO:0048462 +name: carpel formation +namespace: biological_process +alt_id: GO:0048431 +def: "The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts." [GOC:jid] +is_a: GO:0048449 ! floral organ formation +relationship: part_of GO:0048445 ! carpel morphogenesis + +[Term] +id: GO:0048463 +name: carpel structural organization +namespace: biological_process +alt_id: GO:0048432 +def: "The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure." [GOC:jid] +synonym: "carpel structural organisation" EXACT [] +is_a: GO:0048450 ! floral organ structural organization +relationship: part_of GO:0048445 ! carpel morphogenesis + +[Term] +id: GO:0048464 +name: flower calyx development +namespace: biological_process +def: "The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048438 ! floral whorl development + +[Term] +id: GO:0048465 +name: corolla development +namespace: biological_process +def: "The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048438 ! floral whorl development + +[Term] +id: GO:0048466 +name: androecium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure." [GOC:go_curators] +is_a: GO:0048438 ! floral whorl development + +[Term] +id: GO:0048467 +name: gynoecium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower." [GOC:go_curators, PO:0008062] +synonym: "pistil development" EXACT [] +is_a: GO:0048438 ! floral whorl development + +[Term] +id: GO:0048468 +name: cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:go_curators] +subset: goslim_candida +synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +is_a: GO:0048869 ! cellular developmental process +relationship: part_of GO:0030154 ! cell differentiation + +[Term] +id: GO:0048469 +name: cell maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state." [GOC:go_curators] +subset: goslim_pir +synonym: "functional differentiation" RELATED [GOC:dph] +is_a: GO:0048869 ! cellular developmental process +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0048468 ! cell development + +[Term] +id: GO:0048471 +name: perinuclear region of cytoplasm +namespace: cellular_component +def: "Cytoplasm situated near, or occurring around, the nucleus." [GOC:jid] +comment: Note that this term should not be confused with the cellular component term 'nuclear membrane lumen ; GO:0005641', which has the synonym 'perinuclear space'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0048472 +name: threonine-phosphate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2)." [EC:4.1.1.81, RHEA:11492] +synonym: "CobD" RELATED [EC:4.1.1.81] +synonym: "L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]" RELATED [EC:4.1.1.81] +synonym: "L-threonine O-3-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.81] +synonym: "L-threonine-O-3-phosphate decarboxylase activity" EXACT [] +xref: EC:4.1.1.81 +xref: KEGG_REACTION:R06530 +xref: MetaCyc:4.1.1.81-RXN +xref: RHEA:11492 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0048473 +name: D-methionine transport +namespace: biological_process +def: "The directed movement of D-methionine into, out of, within, or between cells." [GOC:mlg, PMID:12169620] +is_a: GO:0015821 ! methionine transport +is_a: GO:0042940 ! D-amino acid transport + +[Term] +id: GO:0048474 +name: D-methionine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-methionine from one side of a membrane to the other." [GOC:mlg, GOC:mtg_transport, ISBN:0815340729] +synonym: "D-methionine transporter activity" BROAD [] +is_a: GO:0042943 ! D-amino acid transmembrane transporter activity +is_a: GO:0043865 ! methionine transmembrane transporter activity +relationship: part_of GO:0048473 ! D-methionine transport + +[Term] +id: GO:0048475 +name: coated membrane +namespace: cellular_component +def: "A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes." [GOC:jid] +is_a: GO:0016020 ! membrane + +[Term] +id: GO:0048476 +name: Holliday junction resolvase complex +namespace: cellular_component +def: "An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated." [PMID:11207366, PMID:12374758] +subset: goslim_pir +synonym: "Mus81-Eme1 complex" NARROW [] +synonym: "Mus81-Eme1 holliday resolvase complex" NARROW [] +synonym: "Mus81-Eme2 complex" NARROW [] +synonym: "Mus81-Eme2 holliday resolvase complex" NARROW [] +synonym: "resolvasome" EXACT [PMID:11207366] +is_a: GO:1905347 ! endodeoxyribonuclease complex + +[Term] +id: GO:0048477 +name: oogenesis +namespace: biological_process +alt_id: GO:0009993 +alt_id: GO:0048157 +def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] +synonym: "ovum development" EXACT systematic_synonym [] +xref: Wikipedia:Oogenesis +is_a: GO:0007281 ! germ cell development +is_a: GO:0007292 ! female gamete generation + +[Term] +id: GO:0048478 +name: replication fork protection +namespace: biological_process +def: "Any process that prevents the collapse of stalled replication forks." [GOC:vw, PMID:14560029] +synonym: "replication fork maintenance" BROAD [] +synonym: "replication fork stabilization" BROAD [] +is_a: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication + +[Term] +id: GO:0048479 +name: style development +namespace: biological_process +def: "The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma." [GOC:jid, PO:0009074] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048440 ! carpel development + +[Term] +id: GO:0048480 +name: stigma development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky." [GOC:jid, PO:0009073] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048440 ! carpel development + +[Term] +id: GO:0048481 +name: plant ovule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0099402 ! plant organ development +relationship: part_of GO:0035670 ! plant-type ovary development + +[Term] +id: GO:0048482 +name: plant ovule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090698 ! post-embryonic plant morphogenesis +is_a: GO:1905392 ! plant organ morphogenesis +relationship: part_of GO:0048445 ! carpel morphogenesis +relationship: part_of GO:0048481 ! plant ovule development + +[Term] +id: GO:0048483 +name: autonomic nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr] +is_a: GO:0048731 ! system development +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0048484 +name: enteric nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation." [FMA:66070, GOC:jid, GOC:sr] +is_a: GO:0048731 ! system development +relationship: part_of GO:0048483 ! autonomic nervous system development + +[Term] +id: GO:0048485 +name: sympathetic nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr] +is_a: GO:0048731 ! system development +relationship: part_of GO:0048483 ! autonomic nervous system development + +[Term] +id: GO:0048486 +name: parasympathetic nervous system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia." [FMA:9907, GOC:jid, GOC:sr] +is_a: GO:0048731 ! system development +relationship: part_of GO:0048483 ! autonomic nervous system development + +[Term] +id: GO:0048487 +name: beta-tubulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin." [GOC:krc] +synonym: "beta tubulin binding" EXACT [] +is_a: GO:0015631 ! tubulin binding + +[Term] +id: GO:0048488 +name: synaptic vesicle endocytosis +namespace: biological_process +alt_id: GO:0008099 +def: "A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms." [GOC:aruk, GOC:bc, GOC:jid, GOC:lmg, GOC:mah, PMID:20448150, PMID:26430111] +subset: goslim_synapse +synonym: "synaptic vesicle retrieval" RELATED [] +is_a: GO:0140238 ! presynaptic endocytosis +relationship: part_of GO:0036465 ! synaptic vesicle recycling +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/230 xsd:anyURI + +[Term] +id: GO:0048489 +name: synaptic vesicle transport +namespace: biological_process +alt_id: GO:0016181 +def: "The directed movement of synaptic vesicles." [GOC:aruk, GOC:bc, GOC:jid, GOC:lmg, GOC:pr] +subset: goslim_synapse +synonym: "synaptic vesicle fission" RELATED [] +synonym: "synaptic vesicle fusion" RELATED [] +synonym: "synaptic vesicle trafficking" RELATED [PMID:15217342] +is_a: GO:0006810 ! transport +is_a: GO:0051650 ! establishment of vesicle localization +is_a: GO:0097479 ! synaptic vesicle localization + +[Term] +id: GO:0048490 +name: anterograde synaptic vesicle transport +namespace: biological_process +def: "The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse." [GOC:jid, GOC:lmg] +subset: goslim_synapse +synonym: "anterograde axonal transport of synaptic vesicle" EXACT [] +is_a: GO:0008089 ! anterograde axonal transport +is_a: GO:0099517 ! synaptic vesicle transport along microtubule + +[Term] +id: GO:0048491 +name: retrograde synaptic vesicle transport +namespace: biological_process +def: "The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body." [GOC:jid, GOC:lmg, PMID:24762653] +subset: goslim_synapse +synonym: "retrograde axonal transport of synaptic vesicle" EXACT [] +is_a: GO:0008090 ! retrograde axonal transport +is_a: GO:0099517 ! synaptic vesicle transport along microtubule + +[Term] +id: GO:0048492 +name: ribulose bisphosphate carboxylase complex +namespace: cellular_component +def: "A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg] +subset: goslim_pir +synonym: "RubisCO complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0048493 +name: plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex +namespace: cellular_component +def: "A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg, GOC:mtg_sensu] +synonym: "plasma membrane ribulose bisphosphate carboxylase complex" EXACT [] +synonym: "ribulose bisphosphate carboxylase complex" BROAD [] +synonym: "RubisCO complex" BROAD [] +is_a: GO:0048494 ! chromatophore ribulose bisphosphate carboxylase complex +is_a: GO:0098797 ! plasma membrane protein complex +intersection_of: GO:0048492 ! ribulose bisphosphate carboxylase complex +intersection_of: part_of GO:0030075 ! bacterial thylakoid +relationship: part_of GO:0030075 ! bacterial thylakoid + +[Term] +id: GO:0048494 +name: chromatophore ribulose bisphosphate carboxylase complex +namespace: cellular_component +def: "A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg, GOC:mtg_sensu] +synonym: "RubisCO complex" BROAD [] +is_a: GO:0048492 ! ribulose bisphosphate carboxylase complex +intersection_of: GO:0048492 ! ribulose bisphosphate carboxylase complex +intersection_of: part_of GO:0042716 ! plasma membrane-derived chromatophore +relationship: part_of GO:0042716 ! plasma membrane-derived chromatophore + +[Term] +id: GO:0048495 +name: Roundabout binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor." [GOC:ecd, PMID:10102268, PMID:10197527] +synonym: "Roundabout receptor binding" RELATED [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0048496 +name: maintenance of animal organ identity +namespace: biological_process +def: "The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] +is_a: GO:0045596 ! negative regulation of cell differentiation +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0048497 +name: maintenance of floral organ identity +namespace: biological_process +def: "The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:PO_curators, GOC:tair_curators, PMID:9090883, PO:0025395] +is_a: GO:0022414 ! reproductive process +is_a: GO:0090700 ! maintenance of plant organ identity +relationship: part_of GO:0048437 ! floral organ development + +[Term] +id: GO:0048498 +name: establishment of petal orientation +namespace: biological_process +def: "The process that determines the orientation of petals with reference to the central axis." [GOC:tb, PMID:10572040] +is_a: GO:0048559 ! establishment of floral organ orientation +relationship: part_of GO:0048446 ! petal morphogenesis + +[Term] +id: GO:0048499 +name: synaptic vesicle membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle." [GOC:dph, GOC:jl, GOC:mah, PMID:10620806] +synonym: "SLMV biogenesis" NARROW [] +synonym: "synaptic vesicle membrane organisation" EXACT [] +synonym: "synaptic vesicle membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0010256 ! endomembrane system organization + +[Term] +id: GO:0048500 +name: signal recognition particle +namespace: cellular_component +def: "A complex of protein and RNA which facilitates translocation of proteins across membranes." [GOC:mlg] +subset: goslim_metagenomics +subset: goslim_pir +xref: Wikipedia:Signal_recognition_particle +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0048501 +name: signal recognition particle, plasma membrane targeting +namespace: cellular_component +def: "A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane." [GOC:mlg, GOC:mtg_sensu] +is_a: GO:0048500 ! signal recognition particle + +[Term] +id: GO:0048502 +name: ATPase-coupled thiamine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015619 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in)." [PMID:9535878, TC:3.A.1.19.1] +synonym: "ATP-dependent thiamine transmembrane transporter activity" EXACT [] +synonym: "thiamin pyrophosphate ABC transporter" NARROW [] +synonym: "thiamin pyrophosphate porter activity" BROAD [] +synonym: "thiamin pyrophosphate transporting ATPase activity" RELATED [] +synonym: "thiamin-transporting ATPase activity" EXACT [] +synonym: "thiamine ABC transporter" NARROW [] +synonym: "thiamine pyrophosphate-transporting ATPase activity" RELATED [] +synonym: "thiamine-transporting ATPase activity" EXACT [] +synonym: "TPP transporting ATPase activity" RELATED [] +xref: RHEA:29811 +is_a: GO:0015234 ! thiamine transmembrane transporter activity +is_a: GO:0140394 ! ATPase-coupled azole transmembrane transporter activity + +[Term] +id: GO:0048503 +name: obsolete GPI anchor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes." [GOC:vw] +comment: This term was made obsolete because it has been widely, and incorrectly, used to annotate proteins that have GPI anchors covalently attached. A new term has been created that can be used to annotate gene products that interact non-covalently with GPI anchors. +synonym: "glycosylphosphatidylinositol binding" EXACT [] +synonym: "GPI anchor binding" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048504 +name: regulation of timing of animal organ formation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] +synonym: "timing of organ biosynthesis" RELATED [] +synonym: "timing of organ formation" RELATED [] +is_a: GO:0003156 ! regulation of animal organ formation +is_a: GO:0040034 ! regulation of development, heterochronic + +[Term] +id: GO:0048505 +name: regulation of timing of cell differentiation +namespace: biological_process +def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] +synonym: "timing of cell differentiation" RELATED [] +is_a: GO:0040034 ! regulation of development, heterochronic +is_a: GO:0045595 ! regulation of cell differentiation + +[Term] +id: GO:0048506 +name: regulation of timing of meristematic phase transition +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point." [GOC:dph, GOC:jid, GOC:tb] +is_a: GO:0040034 ! regulation of development, heterochronic +is_a: GO:0048509 ! regulation of meristem development + +[Term] +id: GO:0048507 +name: meristem development +namespace: biological_process +def: "The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0048508 +name: embryonic meristem development +namespace: biological_process +def: "The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048507 ! meristem development +relationship: part_of GO:0009793 ! embryo development ending in seed dormancy + +[Term] +id: GO:0048509 +name: regulation of meristem development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048507 ! meristem development +relationship: regulates GO:0048507 ! meristem development + +[Term] +id: GO:0048510 +name: regulation of timing of transition from vegetative to reproductive phase +namespace: biological_process +def: "The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs." [GOC:jid, PMID:8974397] +is_a: GO:0048506 ! regulation of timing of meristematic phase transition + +[Term] +id: GO:0048511 +name: rhythmic process +namespace: biological_process +def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid] +subset: goslim_pir +synonym: "rhythm" RELATED [] +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0048512 +name: circadian behavior +namespace: biological_process +def: "The specific behavior of an organism that recurs with a regularity of approximately 24 hours." [GOC:bf, GOC:go_curators, GOC:pr] +synonym: "circadian rhythm behavior" EXACT [] +is_a: GO:0007622 ! rhythmic behavior +is_a: GO:0007623 ! circadian rhythm + +[Term] +id: GO:0048513 +name: animal organ development +namespace: biological_process +def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] +synonym: "development of an organ" EXACT [] +synonym: "organogenesis" EXACT [] +xref: Wikipedia:Organogenesis +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048731 ! system development + +[Term] +id: GO:0048514 +name: blood vessel morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0001568 ! blood vessel development + +[Term] +id: GO:0048515 +name: spermatid differentiation +namespace: biological_process +def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid] +synonym: "spermatid cell differentiation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0007283 ! spermatogenesis + +[Term] +id: GO:0048516 +name: obsolete trichome initiation (sensu Magnoliophyta) +namespace: biological_process +def: "OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398)." [GOC:lr] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "trichome initiation (sensu Magnoliophyta)" EXACT [] +is_obsolete: true +consider: GO:0048629 + +[Term] +id: GO:0048517 +name: obsolete positive regulation of trichome initiation (sensu Magnoliophyta) +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398)." [GOC:lr] +comment: This term was made obsolete because more appropriate terms were created. +synonym: "positive regulation of trichome initiation (sensu Magnoliophyta)" EXACT [] +is_obsolete: true +consider: GO:0048629 + +[Term] +id: GO:0048518 +name: positive regulation of biological process +namespace: biological_process +alt_id: GO:0043119 +def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] +subset: gocheck_do_not_annotate +synonym: "activation of biological process" NARROW [] +synonym: "positive regulation of physiological process" EXACT [] +synonym: "stimulation of biological process" NARROW [] +synonym: "up regulation of biological process" EXACT [] +synonym: "up-regulation of biological process" EXACT [] +synonym: "upregulation of biological process" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008150 ! biological_process +relationship: positively_regulates GO:0008150 ! biological_process + +[Term] +id: GO:0048519 +name: negative regulation of biological process +namespace: biological_process +alt_id: GO:0043118 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] +subset: gocheck_do_not_annotate +synonym: "down regulation of biological process" EXACT [] +synonym: "down-regulation of biological process" EXACT [] +synonym: "downregulation of biological process" EXACT [] +synonym: "inhibition of biological process" NARROW [] +synonym: "negative regulation of physiological process" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008150 ! biological_process +relationship: negatively_regulates GO:0008150 ! biological_process + +[Term] +id: GO:0048520 +name: positive regulation of behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] +synonym: "activation of behavior" NARROW [] +synonym: "stimulation of behavior" NARROW [] +synonym: "up regulation of behavior" EXACT [] +synonym: "up-regulation of behavior" EXACT [] +synonym: "upregulation of behavior" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007610 ! behavior +relationship: positively_regulates GO:0007610 ! behavior + +[Term] +id: GO:0048521 +name: negative regulation of behavior +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] +synonym: "down regulation of behavior" EXACT [] +synonym: "down-regulation of behavior" EXACT [] +synonym: "downregulation of behavior" EXACT [] +synonym: "inhibition of behavior" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007610 ! behavior +relationship: negatively_regulates GO:0007610 ! behavior + +[Term] +id: GO:0048522 +name: positive regulation of cellular process +namespace: biological_process +alt_id: GO:0051242 +def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] +synonym: "activation of cellular process" NARROW [] +synonym: "positive regulation of cellular physiological process" EXACT [] +synonym: "stimulation of cellular process" NARROW [] +synonym: "up regulation of cellular process" EXACT [] +synonym: "up-regulation of cellular process" EXACT [] +synonym: "upregulation of cellular process" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0009987 ! cellular process +relationship: positively_regulates GO:0009987 ! cellular process + +[Term] +id: GO:0048523 +name: negative regulation of cellular process +namespace: biological_process +alt_id: GO:0051243 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] +synonym: "down regulation of cellular process" EXACT [] +synonym: "down-regulation of cellular process" EXACT [] +synonym: "downregulation of cellular process" EXACT [] +synonym: "inhibition of cellular process" NARROW [] +synonym: "negative regulation of cellular physiological process" EXACT [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009987 ! cellular process +relationship: negatively_regulates GO:0009987 ! cellular process + +[Term] +id: GO:0048524 +name: positive regulation of viral process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant." [GOC:bf, GOC:jl] +synonym: "activation of viral life cycle" NARROW [] +synonym: "positive regulation of viral life cycle" NARROW [GOC:tb] +synonym: "positive regulation of viral reproduction" NARROW [GOC:bf, GOC:jl] +synonym: "stimulation of viral life cycle" NARROW [] +synonym: "up regulation of viral life cycle" NARROW [] +synonym: "up-regulation of viral life cycle" NARROW [] +synonym: "upregulation of viral life cycle" NARROW [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016032 ! viral process +relationship: positively_regulates GO:0016032 ! viral process + +[Term] +id: GO:0048525 +name: negative regulation of viral process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant." [GOC:bf, GOC:jl] +synonym: "down regulation of viral life cycle" NARROW [] +synonym: "down-regulation of viral life cycle" NARROW [] +synonym: "downregulation of viral life cycle" NARROW [] +synonym: "inhibition of viral life cycle" NARROW [] +synonym: "negative regulation of viral life cycle" NARROW [GOC:tb] +synonym: "negative regulation of viral reproduction" NARROW [GOC:bf, GOC:jl] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016032 ! viral process +relationship: negatively_regulates GO:0016032 ! viral process + +[Term] +id: GO:0048526 +name: imaginal disc-derived wing expansion +namespace: biological_process +def: "The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing." [GOC:mtg_sensu, GOC:rc] +synonym: "wing expansion" EXACT [] +synonym: "wing inflation" EXACT [] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis + +[Term] +id: GO:0048527 +name: lateral root development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper." [GOC:tb] +is_a: GO:0048528 ! post-embryonic root development + +[Term] +id: GO:0048528 +name: post-embryonic root development +namespace: biological_process +def: "The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure." [GOC:tb] +is_a: GO:0048364 ! root development +is_a: GO:0090696 ! post-embryonic plant organ development + +[Term] +id: GO:0048529 +name: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O." [EC:1.14.13.81, RHEA:33235] +synonym: "magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.81] +synonym: "Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity" EXACT [EC:1.14.13.81] +synonym: "Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity" EXACT [EC:1.14.13.81] +xref: EC:1.14.13.81 +xref: RHEA:33235 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0048530 +name: fruit morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant." [GOC:sm] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0010154 ! fruit development + +[Term] +id: GO:0048531 +name: beta-1,3-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage." [PMID:11551958] +is_a: GO:0008378 ! galactosyltransferase activity + +[Term] +id: GO:0048532 +name: anatomical structure arrangement +namespace: biological_process +def: "The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:go_curators] +synonym: "anatomical structure organization" BROAD [] +synonym: "anatomical structure structural organization" EXACT [] +synonym: "organization of an anatomical structure" EXACT [] +synonym: "structural organization" EXACT [] +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0048533 +name: sporocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores." [GOC:tair_curators] +synonym: "sporocyte development" NARROW [] +synonym: "sporocyte morphogenesis" RELATED [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0048534 +name: hematopoietic or lymphoid organ development +namespace: biological_process +def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] +synonym: "haematopoietic or lymphoid organ development" EXACT [] +synonym: "haemopoietic or lymphoid organ development" EXACT [] +synonym: "hemopoietic or lymphoid organ development" EXACT [] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0002520 ! immune system development + +[Term] +id: GO:0048535 +name: lymph node development +namespace: biological_process +def: "The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes." [GOC:add, ISBN:068340007X, ISBN:0781735149] +synonym: "lymph gland development" BROAD [] +is_a: GO:0048534 ! hematopoietic or lymphoid organ development + +[Term] +id: GO:0048536 +name: spleen development +namespace: biological_process +def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149] +is_a: GO:0048534 ! hematopoietic or lymphoid organ development + +[Term] +id: GO:0048537 +name: mucosal-associated lymphoid tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes." [GOC:add, ISBN:0781735149] +synonym: "BALT development" NARROW [] +synonym: "bronchial-associated lymphoid tissue development" NARROW [] +synonym: "GALT development" NARROW [] +synonym: "gut-associated lymphoid tissue development" NARROW [] +synonym: "NALT development" NARROW [] +synonym: "nasopharyngeal-associated lymphoid tissue development" NARROW [] +is_a: GO:0009888 ! tissue development +is_a: GO:0048534 ! hematopoietic or lymphoid organ development + +[Term] +id: GO:0048538 +name: thymus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components." [GOC:add, ISBN:0781735149] +comment: Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere. +is_a: GO:0048534 ! hematopoietic or lymphoid organ development +is_a: GO:0048732 ! gland development + +[Term] +id: GO:0048539 +name: bone marrow development +namespace: biological_process +def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149] +is_a: GO:0009888 ! tissue development +is_a: GO:0048534 ! hematopoietic or lymphoid organ development +relationship: part_of GO:0060348 ! bone development + +[Term] +id: GO:0048540 +name: bursa of Fabricius development +namespace: biological_process +def: "The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation." [GOC:add, ISBN:0781735149] +is_a: GO:0048534 ! hematopoietic or lymphoid organ development + +[Term] +id: GO:0048541 +name: Peyer's patch development +namespace: biological_process +def: "The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes." [GOC:add, ISBN:0781735149] +synonym: "GALT development" RELATED [] +synonym: "gut-associated lymphoid tissue development" RELATED [] +is_a: GO:0048537 ! mucosal-associated lymphoid tissue development + +[Term] +id: GO:0048542 +name: lymph gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages." [GOC:mtg_sensu, GOC:rc] +synonym: "haematopoietic organ development" BROAD [] +synonym: "haemopoietic organ development" BROAD [] +synonym: "hematopoietic organ development" BROAD [] +synonym: "hemopoietic organ development" BROAD [] +is_a: GO:0048534 ! hematopoietic or lymphoid organ development +is_a: GO:0048732 ! gland development + +[Term] +id: GO:0048543 +name: phytochrome chromophore biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form." [GOC:pj, PMID:2909515] +synonym: "phytochrome chromophore anabolism" EXACT [] +synonym: "phytochrome chromophore biosynthesis" EXACT [] +synonym: "phytochrome chromophore formation" EXACT [] +synonym: "phytochrome chromophore synthesis" EXACT [] +is_a: GO:0046148 ! pigment biosynthetic process + +[Term] +id: GO:0048544 +name: recognition of pollen +namespace: biological_process +alt_id: GO:0009857 +def: "The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species." [GOC:dph, GOC:pj, GOC:tb] +synonym: "pollen recognition" EXACT [] +synonym: "recognition or rejection of self pollen" RELATED [GOC:dph, GOC:tb] +synonym: "self incompatibility" RELATED [] +is_a: GO:0008037 ! cell recognition +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0009875 ! pollen-pistil interaction + +[Term] +id: GO:0048545 +name: response to steroid hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] +synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid + +[Term] +id: GO:0048546 +name: digestive tract morphogenesis +namespace: biological_process +alt_id: GO:0048547 +def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131] +synonym: "alimentary canal morphogenesis" EXACT [] +synonym: "digestive tube morphogenesis" EXACT [] +synonym: "gastrointestinal tract morphogenesis" EXACT [] +synonym: "gut morphogenesis" BROAD [GOC:dph] +synonym: "intestinal morphogenesis" NARROW [] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0048565 ! digestive tract development + +[Term] +id: GO:0048548 +name: regulation of pinocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] +is_a: GO:0030100 ! regulation of endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006907 ! pinocytosis +relationship: regulates GO:0006907 ! pinocytosis + +[Term] +id: GO:0048549 +name: positive regulation of pinocytosis +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] +synonym: "activation of pinocytosis" NARROW [] +synonym: "stimulation of pinocytosis" NARROW [] +synonym: "up regulation of pinocytosis" EXACT [] +synonym: "up-regulation of pinocytosis" EXACT [] +synonym: "upregulation of pinocytosis" EXACT [] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:0048548 ! regulation of pinocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006907 ! pinocytosis +relationship: positively_regulates GO:0006907 ! pinocytosis + +[Term] +id: GO:0048550 +name: negative regulation of pinocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] +synonym: "down regulation of pinocytosis" EXACT [] +synonym: "down-regulation of pinocytosis" EXACT [] +synonym: "downregulation of pinocytosis" EXACT [] +synonym: "inhibition of pinocytosis" NARROW [] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:0048548 ! regulation of pinocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006907 ! pinocytosis +relationship: negatively_regulates GO:0006907 ! pinocytosis + +[Term] +id: GO:0048555 +name: generative cell nucleus +namespace: cellular_component +def: "The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells." [GOC:tair_curators] +synonym: "male germ cell nucleus" BROAD [] +synonym: "sperm cell nucleus" BROAD [] +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0048556 +name: microsporocyte nucleus +namespace: cellular_component +alt_id: GO:0043074 +def: "The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte." [GOC:tair_curators, ISBN:047186840X] +synonym: "microspore mother cell nucleus" EXACT [] +synonym: "pollen mother cell nucleus" EXACT [] +is_a: GO:0005634 ! nucleus + +[Term] +id: GO:0048557 +name: embryonic digestive tract morphogenesis +namespace: biological_process +alt_id: GO:0048558 +def: "The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] +synonym: "embryonic gut morphogenesis" BROAD [GOC:dph] +is_a: GO:0048562 ! embryonic organ morphogenesis +relationship: part_of GO:0048546 ! digestive tract morphogenesis +relationship: part_of GO:0048566 ! embryonic digestive tract development + +[Term] +id: GO:0048559 +name: establishment of floral organ orientation +namespace: biological_process +def: "The process that determines the orientation of the floral organs with reference to the central axis of the flower." [GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090707 ! establishment of plant organ orientation +relationship: part_of GO:0048439 ! flower morphogenesis + +[Term] +id: GO:0048560 +name: establishment of anatomical structure orientation +namespace: biological_process +def: "The process that determines the orientation of an anatomical structure with reference to an axis." [GOC:jid] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0048561 +name: establishment of animal organ orientation +namespace: biological_process +def: "The process that determines the orientation of an animal organ or tissue with reference to an axis." [GOC:jid] +is_a: GO:0048560 ! establishment of anatomical structure orientation +relationship: part_of GO:0009887 ! animal organ morphogenesis + +[Term] +id: GO:0048562 +name: embryonic organ morphogenesis +namespace: biological_process +def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0048568 ! embryonic organ development + +[Term] +id: GO:0048563 +name: post-embryonic animal organ morphogenesis +namespace: biological_process +def: "Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048569 ! post-embryonic animal organ development + +[Term] +id: GO:0048564 +name: photosystem I assembly +namespace: biological_process +alt_id: GO:0010251 +def: "The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane." [GOC:go_curators] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0019684 ! photosynthesis, light reaction + +[Term] +id: GO:0048565 +name: digestive tract development +namespace: biological_process +def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] +synonym: "gut development" BROAD [GOC:dph] +synonym: "intestinal development" NARROW [] +synonym: "intestine development" NARROW [] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0055123 ! digestive system development + +[Term] +id: GO:0048566 +name: embryonic digestive tract development +namespace: biological_process +def: "The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus." [GOC:go_curators] +synonym: "embryonic digestive tract development" BROAD [GOC:dph] +is_a: GO:0048565 ! digestive tract development +is_a: GO:0048568 ! embryonic organ development + +[Term] +id: GO:0048567 +name: ectodermal digestive tract morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm." [GOC:jid] +synonym: "ectodermal gut morphogenesis" RELATED [GOC:dph] +is_a: GO:0007439 ! ectodermal digestive tract development +relationship: part_of GO:0048546 ! digestive tract morphogenesis + +[Term] +id: GO:0048568 +name: embryonic organ development +namespace: biological_process +def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] +synonym: "embryonic organogenesis" EXACT [] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0048569 +name: post-embryonic animal organ development +namespace: biological_process +def: "Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] +synonym: "post-embryonic animal organogenesis" EXACT [] +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0048570 +name: notochord morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid] +is_a: GO:0048562 ! embryonic organ morphogenesis +relationship: part_of GO:0030903 ! notochord development + +[Term] +id: GO:0048571 +name: long-day photoperiodism +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "response to long-day" EXACT [] +synonym: "response to long-day photoperiod" RELATED [] +synonym: "response to short-night" EXACT [] +synonym: "short-night photoperiodism" EXACT [] +is_a: GO:0009648 ! photoperiodism + +[Term] +id: GO:0048572 +name: short-day photoperiodism +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "long-night photoperiodism" EXACT [] +synonym: "response to long-night" EXACT [] +synonym: "response to short-day" EXACT [] +synonym: "response to short-day photoperiod" RELATED [] +is_a: GO:0009648 ! photoperiodism + +[Term] +id: GO:0048573 +name: photoperiodism, flowering +namespace: biological_process +def: "A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "photoperiodic control of flowering time" EXACT [] +synonym: "photoperiodic control of inflorescence development" EXACT [] +synonym: "response to day length, flowering" EXACT [] +synonym: "response to night length, flowering" EXACT [] +synonym: "response to photoperiod, flowering" EXACT [] +is_a: GO:0009648 ! photoperiodism +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0010228 ! vegetative to reproductive phase transition of meristem + +[Term] +id: GO:0048574 +name: long-day photoperiodism, flowering +namespace: biological_process +def: "A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "long-day photoperiodic control of flowering" EXACT [] +synonym: "long-day photoperiodic control of flowering time" EXACT [] +synonym: "long-day photoperiodic control of inflorescence development" EXACT [] +synonym: "response to long-day, flowering" EXACT [] +synonym: "response to short-night, flowering" EXACT [] +synonym: "short-night photoperiodism, flowering" EXACT [] +is_a: GO:0048571 ! long-day photoperiodism +is_a: GO:0048573 ! photoperiodism, flowering + +[Term] +id: GO:0048575 +name: short-day photoperiodism, flowering +namespace: biological_process +def: "A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "long-night photoperiodism, flowering" EXACT [] +synonym: "response to long-night, flowering" EXACT [] +synonym: "response to short-day, flowering" EXACT [] +synonym: "short-day photoperiodic control of flowering" EXACT [] +synonym: "short-day photoperiodic control of flowering time" EXACT [] +synonym: "short-day photoperiodic control of inflorescence development" EXACT [] +is_a: GO:0048572 ! short-day photoperiodism +is_a: GO:0048573 ! photoperiodism, flowering + +[Term] +id: GO:0048576 +name: positive regulation of short-day photoperiodism, flowering +namespace: biological_process +def: "Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "activation of short-day photoperiodism, flowering" NARROW [] +synonym: "stimulation of short-day photoperiodism, flowering" NARROW [] +synonym: "up regulation of short-day photoperiodism, flowering" EXACT [] +synonym: "up-regulation of short-day photoperiodism, flowering" EXACT [] +synonym: "upregulation of short-day photoperiodism, flowering" EXACT [] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0048587 ! regulation of short-day photoperiodism, flowering +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048575 ! short-day photoperiodism, flowering +relationship: positively_regulates GO:0048575 ! short-day photoperiodism, flowering + +[Term] +id: GO:0048577 +name: negative regulation of short-day photoperiodism, flowering +namespace: biological_process +def: "Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "down regulation of short-day photoperiodism, flowering" EXACT [] +synonym: "down-regulation of short-day photoperiodism, flowering" EXACT [] +synonym: "downregulation of short-day photoperiodism, flowering" EXACT [] +synonym: "inhibition of short-day photoperiodism, flowering" NARROW [] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0048587 ! regulation of short-day photoperiodism, flowering +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048575 ! short-day photoperiodism, flowering +relationship: negatively_regulates GO:0048575 ! short-day photoperiodism, flowering + +[Term] +id: GO:0048578 +name: positive regulation of long-day photoperiodism, flowering +namespace: biological_process +def: "Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "activation of long-day photoperiodism, flowering" NARROW [] +synonym: "stimulation of long-day photoperiodism, flowering" NARROW [] +synonym: "up regulation of long-day photoperiodism, flowering" EXACT [] +synonym: "up-regulation of long-day photoperiodism, flowering" EXACT [] +synonym: "upregulation of long-day photoperiodism, flowering" EXACT [] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0048586 ! regulation of long-day photoperiodism, flowering +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048574 ! long-day photoperiodism, flowering +relationship: positively_regulates GO:0048574 ! long-day photoperiodism, flowering + +[Term] +id: GO:0048579 +name: negative regulation of long-day photoperiodism, flowering +namespace: biological_process +def: "Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +synonym: "down regulation of long-day photoperiodism, flowering" EXACT [] +synonym: "down-regulation of long-day photoperiodism, flowering" EXACT [] +synonym: "downregulation of long-day photoperiodism, flowering" EXACT [] +synonym: "inhibition of long-day photoperiodism, flowering" NARROW [] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0048586 ! regulation of long-day photoperiodism, flowering +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048574 ! long-day photoperiodism, flowering +relationship: negatively_regulates GO:0048574 ! long-day photoperiodism, flowering + +[Term] +id: GO:0048580 +name: regulation of post-embryonic development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009791 ! post-embryonic development +relationship: regulates GO:0009791 ! post-embryonic development + +[Term] +id: GO:0048581 +name: negative regulation of post-embryonic development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] +synonym: "down regulation of post-embryonic development" EXACT [] +synonym: "down-regulation of post-embryonic development" EXACT [] +synonym: "downregulation of post-embryonic development" EXACT [] +synonym: "inhibition of post-embryonic development" NARROW [] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009791 ! post-embryonic development +relationship: negatively_regulates GO:0009791 ! post-embryonic development + +[Term] +id: GO:0048582 +name: positive regulation of post-embryonic development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] +synonym: "activation of post-embryonic development" NARROW [] +synonym: "stimulation of post-embryonic development" NARROW [] +synonym: "up regulation of post-embryonic development" EXACT [] +synonym: "up-regulation of post-embryonic development" EXACT [] +synonym: "upregulation of post-embryonic development" EXACT [] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009791 ! post-embryonic development +relationship: positively_regulates GO:0009791 ! post-embryonic development + +[Term] +id: GO:0048583 +name: regulation of response to stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050896 ! response to stimulus +relationship: regulates GO:0050896 ! response to stimulus + +[Term] +id: GO:0048584 +name: positive regulation of response to stimulus +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "activation of response to stimulus" NARROW [] +synonym: "stimulation of response to stimulus" NARROW [] +synonym: "up regulation of response to stimulus" EXACT [] +synonym: "up-regulation of response to stimulus" EXACT [] +synonym: "upregulation of response to stimulus" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050896 ! response to stimulus +relationship: positively_regulates GO:0050896 ! response to stimulus + +[Term] +id: GO:0048585 +name: negative regulation of response to stimulus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "down regulation of response to stimulus" EXACT [] +synonym: "down-regulation of response to stimulus" EXACT [] +synonym: "downregulation of response to stimulus" EXACT [] +synonym: "inhibition of response to stimulus" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050896 ! response to stimulus +relationship: negatively_regulates GO:0050896 ! response to stimulus + +[Term] +id: GO:0048586 +name: regulation of long-day photoperiodism, flowering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +is_a: GO:2000028 ! regulation of photoperiodism, flowering +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048574 ! long-day photoperiodism, flowering +relationship: regulates GO:0048574 ! long-day photoperiodism, flowering + +[Term] +id: GO:0048587 +name: regulation of short-day photoperiodism, flowering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase." [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862] +is_a: GO:2000028 ! regulation of photoperiodism, flowering +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048575 ! short-day photoperiodism, flowering +relationship: regulates GO:0048575 ! short-day photoperiodism, flowering + +[Term] +id: GO:0048588 +name: developmental cell growth +namespace: biological_process +def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] +synonym: "developmental growth of a unicellular organism" EXACT [] +is_a: GO:0016049 ! cell growth +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0048468 ! cell development + +[Term] +id: GO:0048589 +name: developmental growth +namespace: biological_process +def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators] +is_a: GO:0032502 ! developmental process +is_a: GO:0040007 ! growth + +[Term] +id: GO:0048592 +name: eye morphogenesis +namespace: biological_process +alt_id: GO:0048748 +def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu] +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0001654 ! eye development + +[Term] +id: GO:0048593 +name: camera-type eye morphogenesis +namespace: biological_process +alt_id: GO:0048594 +alt_id: GO:0048595 +def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu] +synonym: "camera-style eye morphogenesis" EXACT [GOC:dph] +is_a: GO:0048592 ! eye morphogenesis +relationship: part_of GO:0043010 ! camera-type eye development + +[Term] +id: GO:0048596 +name: embryonic camera-type eye morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu] +synonym: "embryonic eye morphogenesis" BROAD [] +is_a: GO:0048048 ! embryonic eye morphogenesis +relationship: part_of GO:0031076 ! embryonic camera-type eye development +relationship: part_of GO:0048593 ! camera-type eye morphogenesis + +[Term] +id: GO:0048597 +name: post-embryonic camera-type eye morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the eye are generated and organized during post-embryonic development." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] +synonym: "post-embryonic camera-style eye morphogenesis" EXACT [] +synonym: "post-embryonic eye morphogenesis" BROAD [] +is_a: GO:0048050 ! post-embryonic eye morphogenesis +relationship: part_of GO:0031077 ! post-embryonic camera-type eye development +relationship: part_of GO:0048593 ! camera-type eye morphogenesis + +[Term] +id: GO:0048598 +name: embryonic morphogenesis +namespace: biological_process +alt_id: GO:0048828 +def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu] +synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0009790 ! embryo development + +[Term] +id: GO:0048599 +name: oocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators] +is_a: GO:0007281 ! germ cell development +relationship: part_of GO:0009994 ! oocyte differentiation + +[Term] +id: GO:0048600 +name: oocyte fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte." [GOC:go_curators] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0009994 ! oocyte differentiation + +[Term] +id: GO:0048601 +name: oocyte morphogenesis +namespace: biological_process +def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators] +synonym: "oocyte morphogenesis during differentiation" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0048599 ! oocyte development + +[Term] +id: GO:0048608 +name: reproductive structure development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061458 ! reproductive system development + +[Term] +id: GO:0048609 +name: multicellular organismal reproductive process +namespace: biological_process +def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] +synonym: "organismal reproductive process" BROAD [] +synonym: "reproductive process in a multicellular organism" EXACT [] +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0032504 ! multicellular organism reproduction + +[Term] +id: GO:0048610 +name: obsolete cellular process involved in reproduction +namespace: biological_process +def: "OBSOLETE. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism." [GOC:dph, GOC:jid] +comment: This process was made obsolete because we felt it not provide a particularly useful classification, and its very broad logical definition caused regular problems in our inference pipelines. +synonym: "cellular process involved in reproduction" EXACT [] +synonym: "reproductive cellular process" RELATED [GOC:dph, GOC:tb] +is_obsolete: true + +[Term] +id: GO:0048611 +name: embryonic ectodermal digestive tract development +namespace: biological_process +def: "The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure." [GOC:jid, GOC:rc] +synonym: "embryonic ectodermal gut development" RELATED [GOC:dph] +is_a: GO:0048566 ! embryonic digestive tract development +relationship: part_of GO:0007439 ! ectodermal digestive tract development + +[Term] +id: GO:0048612 +name: post-embryonic ectodermal digestive tract development +namespace: biological_process +def: "The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure." [GOC:jid, GOC:rc] +synonym: "post-embryonic ectodermal gut development" RELATED [GOC:dph] +is_a: GO:0048569 ! post-embryonic animal organ development +relationship: part_of GO:0007439 ! ectodermal digestive tract development + +[Term] +id: GO:0048613 +name: embryonic ectodermal digestive tract morphogenesis +namespace: biological_process +def: "The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized." [GOC:jid, GOC:rc] +synonym: "embryonic ectodermal gut morphogenesis" RELATED [GOC:dph] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0048557 ! embryonic digestive tract morphogenesis +relationship: part_of GO:0048567 ! ectodermal digestive tract morphogenesis +relationship: part_of GO:0048611 ! embryonic ectodermal digestive tract development + +[Term] +id: GO:0048614 +name: post-embryonic ectodermal digestive tract morphogenesis +namespace: biological_process +def: "The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized." [GOC:jid, GOC:rc] +synonym: "post-embryonic ectodermal gut morphogenesis" RELATED [GOC:dph] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0048567 ! ectodermal digestive tract morphogenesis +relationship: part_of GO:0048612 ! post-embryonic ectodermal digestive tract development +relationship: part_of GO:0048621 ! post-embryonic digestive tract morphogenesis + +[Term] +id: GO:0048615 +name: embryonic anterior midgut (ectodermal) morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +relationship: part_of GO:0007441 ! anterior midgut (ectodermal) morphogenesis +relationship: part_of GO:0048613 ! embryonic ectodermal digestive tract morphogenesis + +[Term] +id: GO:0048616 +name: post-embryonic anterior midgut (ectodermal) morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007441 ! anterior midgut (ectodermal) morphogenesis +relationship: part_of GO:0048614 ! post-embryonic ectodermal digestive tract morphogenesis + +[Term] +id: GO:0048617 +name: embryonic foregut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007440 ! foregut morphogenesis + +[Term] +id: GO:0048618 +name: post-embryonic foregut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007440 ! foregut morphogenesis + +[Term] +id: GO:0048619 +name: embryonic hindgut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007442 ! hindgut morphogenesis + +[Term] +id: GO:0048620 +name: post-embryonic hindgut morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase." [GOC:jid, GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007442 ! hindgut morphogenesis + +[Term] +id: GO:0048621 +name: post-embryonic digestive tract morphogenesis +namespace: biological_process +def: "The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:jid, GOC:rc] +synonym: "post-embryonic gut morphogenesis" BROAD [GOC:dph] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0048546 ! digestive tract morphogenesis + +[Term] +id: GO:0048622 +name: obsolete reproductive sporulation +namespace: biological_process +def: "OBSOLETE. The formation of reproductive spores." [GOC:jid] +comment: This term was made obsolete because it was ambiguously defined and incorrectly placed in the ontology. +synonym: "reproductive sporulation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048623 +name: seed germination on parent plant +namespace: biological_process +def: "The process in which a seed germinates before being shed from the parent plant." [GOC:go_curators] +synonym: "non-vegetative vivipary" BROAD [] +synonym: "pre-harvest sprouting" EXACT [] +synonym: "vivipary" BROAD [] +is_a: GO:0009845 ! seed germination + +[Term] +id: GO:0048624 +name: plantlet formation on parent plant +namespace: biological_process +def: "The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed." [GOC:go_curators] +synonym: "vegetative vivipary" BROAD [] +synonym: "vivipary" BROAD [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0019954 ! asexual reproduction +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process +is_a: GO:0048507 ! meristem development +is_a: GO:0048609 ! multicellular organismal reproductive process + +[Term] +id: GO:0048625 +name: myoblast fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0048626 +name: myoblast fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0048625 ! myoblast fate commitment + +[Term] +id: GO:0048627 +name: myoblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0048628 +name: myoblast maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0048627 ! myoblast development + +[Term] +id: GO:0048629 +name: trichome patterning +namespace: biological_process +def: "The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes." [GOC:jid, GOC:mtg_sensu, GOC:sm, GOC:tb, ISBN:0865427429, PMID:10368181] +synonym: "trichome distribution" BROAD [] +synonym: "trichome pattern biosynthesis" EXACT [] +synonym: "trichome pattern formation" EXACT [] +synonym: "trichome pattern specification" RELATED [] +synonym: "trichome spacing" EXACT [] +is_a: GO:0003002 ! regionalization +is_a: GO:0045168 ! cell-cell signaling involved in cell fate commitment +relationship: part_of GO:0010026 ! trichome differentiation + +[Term] +id: GO:0048630 +name: skeletal muscle tissue growth +namespace: biological_process +def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921] +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0048631 +name: regulation of skeletal muscle tissue growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048630 ! skeletal muscle tissue growth +relationship: regulates GO:0048630 ! skeletal muscle tissue growth + +[Term] +id: GO:0048632 +name: negative regulation of skeletal muscle tissue growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] +synonym: "down regulation of skeletal muscle growth" EXACT [] +synonym: "down-regulation of skeletal muscle growth" EXACT [] +synonym: "downregulation of skeletal muscle growth" EXACT [] +synonym: "inhibition of skeletal muscle growth" NARROW [] +is_a: GO:0048631 ! regulation of skeletal muscle tissue growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0048642 ! negative regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048630 ! skeletal muscle tissue growth +relationship: negatively_regulates GO:0048630 ! skeletal muscle tissue growth + +[Term] +id: GO:0048633 +name: positive regulation of skeletal muscle tissue growth +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] +synonym: "activation of skeletal muscle growth" NARROW [] +synonym: "stimulation of skeletal muscle growth" NARROW [] +synonym: "up regulation of skeletal muscle growth" EXACT [] +synonym: "up-regulation of skeletal muscle growth" EXACT [] +synonym: "upregulation of skeletal muscle growth" EXACT [] +is_a: GO:0048631 ! regulation of skeletal muscle tissue growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048630 ! skeletal muscle tissue growth +relationship: positively_regulates GO:0048630 ! skeletal muscle tissue growth + +[Term] +id: GO:0048634 +name: regulation of muscle organ development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007517 ! muscle organ development +relationship: regulates GO:0007517 ! muscle organ development + +[Term] +id: GO:0048635 +name: negative regulation of muscle organ development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators] +synonym: "down regulation of muscle development" EXACT [] +synonym: "down-regulation of muscle development" EXACT [] +synonym: "downregulation of muscle development" EXACT [] +synonym: "inhibition of muscle development" NARROW [] +is_a: GO:0048634 ! regulation of muscle organ development +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007517 ! muscle organ development +relationship: negatively_regulates GO:0007517 ! muscle organ development + +[Term] +id: GO:0048636 +name: positive regulation of muscle organ development +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] +synonym: "activation of muscle development" NARROW [] +synonym: "stimulation of muscle development" NARROW [] +synonym: "up regulation of muscle development" EXACT [] +synonym: "up-regulation of muscle development" EXACT [] +synonym: "upregulation of muscle development" EXACT [] +is_a: GO:0048634 ! regulation of muscle organ development +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007517 ! muscle organ development +relationship: positively_regulates GO:0007517 ! muscle organ development + +[Term] +id: GO:0048638 +name: regulation of developmental growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators] +is_a: GO:0040008 ! regulation of growth +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048589 ! developmental growth +relationship: regulates GO:0048589 ! developmental growth + +[Term] +id: GO:0048639 +name: positive regulation of developmental growth +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators] +synonym: "activation of developmental growth" NARROW [] +synonym: "stimulation of developmental growth" NARROW [] +synonym: "up regulation of developmental growth" EXACT [] +synonym: "up-regulation of developmental growth" EXACT [] +synonym: "upregulation of developmental growth" EXACT [] +is_a: GO:0045927 ! positive regulation of growth +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0051094 ! positive regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048589 ! developmental growth +relationship: positively_regulates GO:0048589 ! developmental growth + +[Term] +id: GO:0048640 +name: negative regulation of developmental growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators] +synonym: "down regulation of developmental growth" EXACT [] +synonym: "down-regulation of developmental growth" EXACT [] +synonym: "downregulation of developmental growth" EXACT [] +synonym: "inhibition of developmental growth" NARROW [] +is_a: GO:0045926 ! negative regulation of growth +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0051093 ! negative regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048589 ! developmental growth +relationship: negatively_regulates GO:0048589 ! developmental growth + +[Term] +id: GO:0048641 +name: regulation of skeletal muscle tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] +is_a: GO:0016202 ! regulation of striated muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007519 ! skeletal muscle tissue development +relationship: regulates GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0048642 +name: negative regulation of skeletal muscle tissue development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] +synonym: "down regulation of skeletal muscle development" EXACT [] +synonym: "down-regulation of skeletal muscle development" EXACT [] +synonym: "downregulation of skeletal muscle development" EXACT [] +synonym: "inhibition of skeletal muscle development" NARROW [] +is_a: GO:0045843 ! negative regulation of striated muscle tissue development +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007519 ! skeletal muscle tissue development +relationship: negatively_regulates GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0048643 +name: positive regulation of skeletal muscle tissue development +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators] +synonym: "activation of skeletal muscle development" NARROW [] +synonym: "stimulation of skeletal muscle development" NARROW [] +synonym: "up regulation of skeletal muscle development" EXACT [] +synonym: "up-regulation of skeletal muscle development" EXACT [] +synonym: "upregulation of skeletal muscle development" EXACT [] +is_a: GO:0045844 ! positive regulation of striated muscle tissue development +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007519 ! skeletal muscle tissue development +relationship: positively_regulates GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0048644 +name: muscle organ morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0007517 ! muscle organ development + +[Term] +id: GO:0048645 +name: animal organ formation +namespace: biological_process +def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid] +synonym: "animal organ primordium initiation" NARROW [] +synonym: "initiation of an animal organ primordium" NARROW [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0009887 ! animal organ morphogenesis + +[Term] +id: GO:0048646 +name: anatomical structure formation involved in morphogenesis +namespace: biological_process +def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb] +comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. +subset: goslim_chembl +subset: goslim_generic +synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0048647 +name: polyphenic determination +namespace: biological_process +def: "The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues." [GOC:jid] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0048648 +name: caste determination +namespace: biological_process +def: "The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects." [GOC:jid] +is_a: GO:0048647 ! polyphenic determination + +[Term] +id: GO:0048649 +name: caste determination, influence by genetic factors +namespace: biological_process +def: "The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects." [GOC:jid] +is_a: GO:0048648 ! caste determination +is_a: GO:0048652 ! polyphenic determination, influence by genetic factors + +[Term] +id: GO:0048650 +name: caste determination, influence by environmental factors +namespace: biological_process +def: "The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects." [GOC:jid] +is_a: GO:0048648 ! caste determination +is_a: GO:0048651 ! polyphenic determination, influence by environmental factors + +[Term] +id: GO:0048651 +name: polyphenic determination, influence by environmental factors +namespace: biological_process +def: "The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues." [GOC:jid] +is_a: GO:0009605 ! response to external stimulus +is_a: GO:0048647 ! polyphenic determination + +[Term] +id: GO:0048652 +name: polyphenic determination, influence by genetic factors +namespace: biological_process +def: "The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues." [GOC:jid] +is_a: GO:0048647 ! polyphenic determination + +[Term] +id: GO:0048653 +name: anther development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure." [GOC:jid, GOC:sm] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048443 ! stamen development + +[Term] +id: GO:0048654 +name: anther morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anther are generated and organized." [GOC:jid, GOC:sm] +is_a: GO:0048444 ! floral organ morphogenesis +relationship: part_of GO:0048448 ! stamen morphogenesis +relationship: part_of GO:0048653 ! anther development + +[Term] +id: GO:0048655 +name: anther wall tapetum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature." [GOC:jid, GOC:sm, GOC:tb] +synonym: "differentiation of tapetal layer" NARROW [] +synonym: "tapetal layer morphogenesis" BROAD [GOC:tb] +synonym: "tapetum morphogenesis" BROAD [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0048654 ! anther morphogenesis +relationship: part_of GO:0048658 ! anther wall tapetum development + +[Term] +id: GO:0048656 +name: anther wall tapetum formation +namespace: biological_process +def: "The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature." [GOC:jid, GOC:sm, GOC:tb] +synonym: "tapetal layer formation" BROAD [GOC:tb] +synonym: "tapetum formation" BROAD [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048455 ! stamen formation +relationship: part_of GO:0048655 ! anther wall tapetum morphogenesis + +[Term] +id: GO:0048657 +name: anther wall tapetum cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature." [GOC:jid, GOC:sm] +synonym: "tapetal cell differentiation" BROAD [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048656 ! anther wall tapetum formation + +[Term] +id: GO:0048658 +name: anther wall tapetum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure." [GOC:jid, GOC:sm, GOC:tb] +synonym: "tapetal layer development" BROAD [GOC:tb] +synonym: "tapetum development" BROAD [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048653 ! anther development + +[Term] +id: GO:0048659 +name: smooth muscle cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] +synonym: "SMC proliferation" EXACT [] +is_a: GO:0033002 ! muscle cell proliferation + +[Term] +id: GO:0048660 +name: regulation of smooth muscle cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] +synonym: "regulation of SMC proliferation" EXACT [] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048659 ! smooth muscle cell proliferation +relationship: regulates GO:0048659 ! smooth muscle cell proliferation + +[Term] +id: GO:0048661 +name: positive regulation of smooth muscle cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] +synonym: "activation of smooth muscle cell proliferation" NARROW [] +synonym: "positive regulation of SMC proliferation" EXACT [] +synonym: "stimulation of smooth muscle cell proliferation" NARROW [] +synonym: "up regulation of smooth muscle cell proliferation" EXACT [] +synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] +synonym: "upregulation of smooth muscle cell proliferation" EXACT [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0048660 ! regulation of smooth muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048659 ! smooth muscle cell proliferation +relationship: positively_regulates GO:0048659 ! smooth muscle cell proliferation + +[Term] +id: GO:0048662 +name: negative regulation of smooth muscle cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] +synonym: "down regulation of smooth muscle cell proliferation" EXACT [] +synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] +synonym: "downregulation of smooth muscle cell proliferation" EXACT [] +synonym: "inhibition of smooth muscle cell proliferation" NARROW [] +synonym: "negative regulation of SMC proliferation" EXACT [] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0048660 ! regulation of smooth muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048659 ! smooth muscle cell proliferation +relationship: negatively_regulates GO:0048659 ! smooth muscle cell proliferation + +[Term] +id: GO:0048663 +name: neuron fate commitment +namespace: biological_process +alt_id: GO:0042055 +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron." [GOC:dph] +synonym: "neuron lineage restriction" EXACT [] +synonym: "neuronal lineage restriction" EXACT [] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0030182 ! neuron differentiation + +[Term] +id: GO:0048664 +name: neuron fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:dph] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0048663 ! neuron fate commitment + +[Term] +id: GO:0048665 +name: neuron fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GOC:dph] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0048663 ! neuron fate commitment + +[Term] +id: GO:0048666 +name: neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0030182 ! neuron differentiation + +[Term] +id: GO:0048667 +name: cell morphogenesis involved in neuron differentiation +namespace: biological_process +def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb] +synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0030182 ! neuron differentiation +relationship: part_of GO:0048666 ! neuron development + +[Term] +id: GO:0048668 +name: collateral sprouting +namespace: biological_process +def: "The process in which outgrowths develop from the shafts of existing axons." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "axon branching" BROAD [GOC:BHF, PMID:21463686] +is_a: GO:0048588 ! developmental cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0007409 ! axonogenesis + +[Term] +id: GO:0048669 +name: collateral sprouting in absence of injury +namespace: biological_process +def: "The process in which outgrowths develop from the axons of intact undamaged neurons." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048668 ! collateral sprouting + +[Term] +id: GO:0048670 +name: regulation of collateral sprouting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0050770 ! regulation of axonogenesis +is_a: GO:0061387 ! regulation of extent of cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048668 ! collateral sprouting +relationship: regulates GO:0048668 ! collateral sprouting + +[Term] +id: GO:0048671 +name: negative regulation of collateral sprouting +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of collateral sprouting" EXACT [] +synonym: "down-regulation of collateral sprouting" EXACT [] +synonym: "downregulation of collateral sprouting" EXACT [] +synonym: "inhibition of collateral sprouting" NARROW [] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0048670 ! regulation of collateral sprouting +is_a: GO:0050771 ! negative regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048668 ! collateral sprouting +relationship: negatively_regulates GO:0048668 ! collateral sprouting + +[Term] +id: GO:0048672 +name: positive regulation of collateral sprouting +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of collateral sprouting" NARROW [] +synonym: "stimulation of collateral sprouting" NARROW [] +synonym: "up regulation of collateral sprouting" EXACT [] +synonym: "up-regulation of collateral sprouting" EXACT [] +synonym: "upregulation of collateral sprouting" EXACT [] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0048670 ! regulation of collateral sprouting +is_a: GO:0050772 ! positive regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048668 ! collateral sprouting +relationship: positively_regulates GO:0048668 ! collateral sprouting + +[Term] +id: GO:0048673 +name: collateral sprouting of intact axon in response to injury +namespace: biological_process +def: "The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input." [GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0031103 ! axon regeneration +is_a: GO:0048668 ! collateral sprouting + +[Term] +id: GO:0048674 +name: collateral sprouting of injured axon +namespace: biological_process +def: "The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048668 ! collateral sprouting +is_a: GO:0048682 ! sprouting of injured axon + +[Term] +id: GO:0048675 +name: axon extension +namespace: biological_process +alt_id: GO:0048676 +def: "Long distance growth of a single axon process involved in cellular development." [GOC:BHF, GOC:dgh, GOC:dph, GOC:jid, GOC:lm, GOC:rl] +synonym: "axon extension involved in development" EXACT [] +is_a: GO:1990138 ! neuron projection extension +relationship: part_of GO:0007409 ! axonogenesis + +[Term] +id: GO:0048677 +name: axon extension involved in regeneration +namespace: biological_process +def: "Long distance growth of a single axon process involved in regeneration of the neuron." [GOC:jid] +is_a: GO:0048675 ! axon extension +is_a: GO:0048682 ! sprouting of injured axon +intersection_of: GO:0048675 ! axon extension +intersection_of: part_of GO:0031099 ! regeneration + +[Term] +id: GO:0048678 +name: response to axon injury +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0009611 ! response to wounding + +[Term] +id: GO:0048679 +name: regulation of axon regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0070570 ! regulation of neuron projection regeneration +is_a: GO:1903034 ! regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031103 ! axon regeneration +relationship: regulates GO:0031103 ! axon regeneration + +[Term] +id: GO:0048680 +name: positive regulation of axon regeneration +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of axon regeneration" NARROW [] +synonym: "stimulation of axon regeneration" NARROW [] +synonym: "up regulation of axon regeneration" EXACT [] +synonym: "up-regulation of axon regeneration" EXACT [] +synonym: "upregulation of axon regeneration" EXACT [] +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0048679 ! regulation of axon regeneration +is_a: GO:0070572 ! positive regulation of neuron projection regeneration +is_a: GO:1903036 ! positive regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031103 ! axon regeneration +relationship: positively_regulates GO:0031103 ! axon regeneration + +[Term] +id: GO:0048681 +name: negative regulation of axon regeneration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of axon regeneration" EXACT [] +synonym: "down-regulation of axon regeneration" EXACT [] +synonym: "downregulation of axon regeneration" EXACT [] +synonym: "inhibition of axon regeneration" NARROW [] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0048679 ! regulation of axon regeneration +is_a: GO:0070571 ! negative regulation of neuron projection regeneration +is_a: GO:1903035 ! negative regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031103 ! axon regeneration +relationship: negatively_regulates GO:0031103 ! axon regeneration + +[Term] +id: GO:0048682 +name: sprouting of injured axon +namespace: biological_process +def: "The process involved in sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048588 ! developmental cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0031103 ! axon regeneration + +[Term] +id: GO:0048683 +name: regulation of collateral sprouting of intact axon in response to injury +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048670 ! regulation of collateral sprouting +is_a: GO:0048679 ! regulation of axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048673 ! collateral sprouting of intact axon in response to injury +relationship: regulates GO:0048673 ! collateral sprouting of intact axon in response to injury + +[Term] +id: GO:0048684 +name: positive regulation of collateral sprouting of intact axon in response to injury +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of collateral sprouting of intact axon in response to injury" NARROW [] +synonym: "stimulation of collateral sprouting of intact axon in response to injury" NARROW [] +synonym: "up regulation of collateral sprouting of intact axon in response to injury" EXACT [] +synonym: "up-regulation of collateral sprouting of intact axon in response to injury" EXACT [] +synonym: "upregulation of collateral sprouting of intact axon in response to injury" EXACT [] +is_a: GO:0048672 ! positive regulation of collateral sprouting +is_a: GO:0048680 ! positive regulation of axon regeneration +is_a: GO:0048683 ! regulation of collateral sprouting of intact axon in response to injury +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048673 ! collateral sprouting of intact axon in response to injury +relationship: positively_regulates GO:0048673 ! collateral sprouting of intact axon in response to injury + +[Term] +id: GO:0048685 +name: negative regulation of collateral sprouting of intact axon in response to injury +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of collateral sprouting of intact axon in response to injury" EXACT [] +synonym: "down-regulation of collateral sprouting of intact axon in response to injury" EXACT [] +synonym: "downregulation of collateral sprouting of intact axon in response to injury" EXACT [] +synonym: "inhibition of collateral sprouting of intact axon in response to injury" NARROW [] +is_a: GO:0048671 ! negative regulation of collateral sprouting +is_a: GO:0048681 ! negative regulation of axon regeneration +is_a: GO:0048683 ! regulation of collateral sprouting of intact axon in response to injury +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048673 ! collateral sprouting of intact axon in response to injury +relationship: negatively_regulates GO:0048673 ! collateral sprouting of intact axon in response to injury + +[Term] +id: GO:0048686 +name: regulation of sprouting of injured axon +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0048679 ! regulation of axon regeneration +is_a: GO:0061387 ! regulation of extent of cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048682 ! sprouting of injured axon +relationship: regulates GO:0048682 ! sprouting of injured axon + +[Term] +id: GO:0048687 +name: positive regulation of sprouting of injured axon +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of sprouting of injured axon" NARROW [] +synonym: "stimulation of sprouting of injured axon" NARROW [] +synonym: "up regulation of sprouting of injured axon" EXACT [] +synonym: "up-regulation of sprouting of injured axon" EXACT [] +synonym: "upregulation of sprouting of injured axon" EXACT [] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0048680 ! positive regulation of axon regeneration +is_a: GO:0048686 ! regulation of sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048682 ! sprouting of injured axon +relationship: positively_regulates GO:0048682 ! sprouting of injured axon + +[Term] +id: GO:0048688 +name: negative regulation of sprouting of injured axon +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of sprouting of injured axon" EXACT [] +synonym: "down-regulation of sprouting of injured axon" EXACT [] +synonym: "downregulation of sprouting of injured axon" EXACT [] +synonym: "inhibition of sprouting of injured axon" NARROW [] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0048681 ! negative regulation of axon regeneration +is_a: GO:0048686 ! regulation of sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048682 ! sprouting of injured axon +relationship: negatively_regulates GO:0048682 ! sprouting of injured axon + +[Term] +id: GO:0048689 +name: formation of growth cone in injured axon +namespace: biological_process +def: "The formation of a growth cone in an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048682 ! sprouting of injured axon + +[Term] +id: GO:0048690 +name: regulation of axon extension involved in regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0030516 ! regulation of axon extension +is_a: GO:0048686 ! regulation of sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048677 ! axon extension involved in regeneration +relationship: regulates GO:0048677 ! axon extension involved in regeneration + +[Term] +id: GO:0048691 +name: positive regulation of axon extension involved in regeneration +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of axon extension involved in regeneration" NARROW [] +synonym: "stimulation of axon extension involved in regeneration" NARROW [] +synonym: "up regulation of axon extension involved in regeneration" EXACT [] +synonym: "up-regulation of axon extension involved in regeneration" EXACT [] +synonym: "upregulation of axon extension involved in regeneration" EXACT [] +is_a: GO:0045773 ! positive regulation of axon extension +is_a: GO:0048687 ! positive regulation of sprouting of injured axon +is_a: GO:0048690 ! regulation of axon extension involved in regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048677 ! axon extension involved in regeneration +relationship: positively_regulates GO:0048677 ! axon extension involved in regeneration + +[Term] +id: GO:0048692 +name: negative regulation of axon extension involved in regeneration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of axon extension involved in regeneration" EXACT [] +synonym: "down-regulation of axon extension involved in regeneration" EXACT [] +synonym: "downregulation of axon extension involved in regeneration" EXACT [] +synonym: "inhibition of axon extension involved in regeneration" NARROW [] +is_a: GO:0030517 ! negative regulation of axon extension +is_a: GO:0048688 ! negative regulation of sprouting of injured axon +is_a: GO:0048690 ! regulation of axon extension involved in regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048677 ! axon extension involved in regeneration +relationship: negatively_regulates GO:0048677 ! axon extension involved in regeneration + +[Term] +id: GO:0048693 +name: regulation of collateral sprouting of injured axon +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048670 ! regulation of collateral sprouting +is_a: GO:0048686 ! regulation of sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048674 ! collateral sprouting of injured axon +relationship: regulates GO:0048674 ! collateral sprouting of injured axon + +[Term] +id: GO:0048694 +name: positive regulation of collateral sprouting of injured axon +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of collateral sprouting of injured axon" NARROW [] +synonym: "stimulation of collateral sprouting of injured axon" NARROW [] +synonym: "up regulation of collateral sprouting of injured axon" EXACT [] +synonym: "up-regulation of collateral sprouting of injured axon" EXACT [] +synonym: "upregulation of collateral sprouting of injured axon" EXACT [] +is_a: GO:0048672 ! positive regulation of collateral sprouting +is_a: GO:0048687 ! positive regulation of sprouting of injured axon +is_a: GO:0048693 ! regulation of collateral sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048674 ! collateral sprouting of injured axon +relationship: positively_regulates GO:0048674 ! collateral sprouting of injured axon + +[Term] +id: GO:0048695 +name: negative regulation of collateral sprouting of injured axon +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of collateral sprouting of injured axon" EXACT [] +synonym: "down-regulation of collateral sprouting of injured axon" EXACT [] +synonym: "downregulation of collateral sprouting of injured axon" EXACT [] +synonym: "inhibition of collateral sprouting of injured axon" NARROW [] +is_a: GO:0048671 ! negative regulation of collateral sprouting +is_a: GO:0048688 ! negative regulation of sprouting of injured axon +is_a: GO:0048693 ! regulation of collateral sprouting of injured axon +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048674 ! collateral sprouting of injured axon +relationship: negatively_regulates GO:0048674 ! collateral sprouting of injured axon + +[Term] +id: GO:0048696 +name: regulation of collateral sprouting in absence of injury +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0048670 ! regulation of collateral sprouting +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048669 ! collateral sprouting in absence of injury +relationship: regulates GO:0048669 ! collateral sprouting in absence of injury + +[Term] +id: GO:0048697 +name: positive regulation of collateral sprouting in absence of injury +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "activation of collateral sprouting in the absence of injury" NARROW [] +synonym: "stimulation of collateral sprouting in the absence of injury" NARROW [] +synonym: "up regulation of collateral sprouting in the absence of injury" EXACT [] +synonym: "up-regulation of collateral sprouting in the absence of injury" EXACT [] +synonym: "upregulation of collateral sprouting in the absence of injury" EXACT [] +is_a: GO:0048672 ! positive regulation of collateral sprouting +is_a: GO:0048696 ! regulation of collateral sprouting in absence of injury +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048669 ! collateral sprouting in absence of injury +relationship: positively_regulates GO:0048669 ! collateral sprouting in absence of injury + +[Term] +id: GO:0048698 +name: negative regulation of collateral sprouting in absence of injury +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jid, GOC:lm] +synonym: "down regulation of collateral sprouting in the absence of injury" EXACT [] +synonym: "down-regulation of collateral sprouting in the absence of injury" EXACT [] +synonym: "downregulation of collateral sprouting in the absence of injury" EXACT [] +synonym: "inhibition of collateral sprouting in the absence of injury" NARROW [] +is_a: GO:0048671 ! negative regulation of collateral sprouting +is_a: GO:0048696 ! regulation of collateral sprouting in absence of injury +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048669 ! collateral sprouting in absence of injury +relationship: negatively_regulates GO:0048669 ! collateral sprouting in absence of injury + +[Term] +id: GO:0048699 +name: generation of neurons +namespace: biological_process +def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln] +synonym: "neuron generation" EXACT [] +is_a: GO:0022008 ! neurogenesis + +[Term] +id: GO:0048700 +name: acquisition of desiccation tolerance in seed +namespace: biological_process +def: "The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state." [GOC:jid, GOC:ki, GOC:PO_curators, ISBN:9781405139830] +synonym: "acquisition of desiccation tolerance" BROAD [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0097439 ! acquisition of desiccation tolerance +relationship: part_of GO:0010162 ! seed dormancy process + +[Term] +id: GO:0048701 +name: embryonic cranial skeleton morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase." [GOC:dsf, GOC:jid, PMID:16049113] +synonym: "embryonic cranium morphogenesis" EXACT [] +is_a: GO:0048704 ! embryonic skeletal system morphogenesis +relationship: part_of GO:1904888 ! cranial skeletal system development + +[Term] +id: GO:0048702 +name: embryonic neurocranium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain." [GOC:dsf, GOC:jid, PMID:16049113] +synonym: "embryonic braincase morphogenesis" EXACT [] +synonym: "embryonic chondrocranium morphogenesis" EXACT [GOC:dph] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0048701 ! embryonic cranial skeleton morphogenesis + +[Term] +id: GO:0048703 +name: embryonic viscerocranium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones." [GOC:dsf, GOC:jid, PMID:16049113] +synonym: "embryonic pharyngeal skeleton morphogenesis" EXACT [] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0048701 ! embryonic cranial skeleton morphogenesis + +[Term] +id: GO:0048704 +name: embryonic skeletal system morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb, PMID:16049113] +synonym: "embryonic skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0048562 ! embryonic organ morphogenesis +is_a: GO:0048705 ! skeletal system morphogenesis +relationship: part_of GO:0048706 ! embryonic skeletal system development + +[Term] +id: GO:0048705 +name: skeletal system morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb] +synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0001501 ! skeletal system development + +[Term] +id: GO:0048706 +name: embryonic skeletal system development +namespace: biological_process +def: "The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb, PMID:16049113] +synonym: "embryonic skeletal development" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001501 ! skeletal system development +relationship: part_of GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0048707 +name: instar larval or pupal morphogenesis +namespace: biological_process +def: "The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized." [GOC:mtg_sensu, GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0002165 ! instar larval or pupal development + +[Term] +id: GO:0048708 +name: astrocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function." [GOC:vp, PMID:15139015] +is_a: GO:0010001 ! glial cell differentiation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0048709 +name: oligodendrocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system." [GOC:vp, PMID:15139015] +is_a: GO:0010001 ! glial cell differentiation +relationship: part_of GO:0007417 ! central nervous system development + +[Term] +id: GO:0048710 +name: regulation of astrocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048708 ! astrocyte differentiation +relationship: regulates GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0048711 +name: positive regulation of astrocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] +synonym: "activation of astrocyte differentiation" NARROW [] +synonym: "stimulation of astrocyte differentiation" NARROW [] +synonym: "up regulation of astrocyte differentiation" EXACT [] +synonym: "up-regulation of astrocyte differentiation" EXACT [] +synonym: "upregulation of astrocyte differentiation" EXACT [] +is_a: GO:0045687 ! positive regulation of glial cell differentiation +is_a: GO:0048710 ! regulation of astrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048708 ! astrocyte differentiation +relationship: positively_regulates GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0048712 +name: negative regulation of astrocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] +synonym: "down regulation of astrocyte differentiation" EXACT [] +synonym: "down-regulation of astrocyte differentiation" EXACT [] +synonym: "downregulation of astrocyte differentiation" EXACT [] +synonym: "inhibition of astrocyte differentiation" NARROW [] +is_a: GO:0045686 ! negative regulation of glial cell differentiation +is_a: GO:0048710 ! regulation of astrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048708 ! astrocyte differentiation +relationship: negatively_regulates GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0048713 +name: regulation of oligodendrocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] +is_a: GO:0045685 ! regulation of glial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048709 ! oligodendrocyte differentiation +relationship: regulates GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0048714 +name: positive regulation of oligodendrocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] +synonym: "activation of oligodendrocyte differentiation" NARROW [] +synonym: "stimulation of oligodendrocyte differentiation" NARROW [] +synonym: "up regulation of oligodendrocyte differentiation" EXACT [] +synonym: "up-regulation of oligodendrocyte differentiation" EXACT [] +synonym: "upregulation of oligodendrocyte differentiation" EXACT [] +is_a: GO:0045687 ! positive regulation of glial cell differentiation +is_a: GO:0048713 ! regulation of oligodendrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048709 ! oligodendrocyte differentiation +relationship: positively_regulates GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0048715 +name: negative regulation of oligodendrocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] +synonym: "down regulation of oligodendrocyte differentiation" EXACT [] +synonym: "down-regulation of oligodendrocyte differentiation" EXACT [] +synonym: "downregulation of oligodendrocyte differentiation" EXACT [] +synonym: "inhibition of oligodendrocyte differentiation" NARROW [] +is_a: GO:0045686 ! negative regulation of glial cell differentiation +is_a: GO:0048713 ! regulation of oligodendrocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048709 ! oligodendrocyte differentiation +relationship: negatively_regulates GO:0048709 ! oligodendrocyte differentiation + +[Term] +id: GO:0048716 +name: labrum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of labrum are generated and organized." [GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048726 ! labrum development + +[Term] +id: GO:0048717 +name: anterior cibarial plate morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the anterior cibarial plate are generated and organized." [GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048722 ! anterior cibarial plate development + +[Term] +id: GO:0048718 +name: cibarial fish-trap bristle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium." [FBbt:00004136, GOC:rc] +synonym: "fish trap bristle morphogenesis" RELATED [GOC:rc] +is_a: GO:0008407 ! chaeta morphogenesis +is_a: GO:0048563 ! post-embryonic animal organ morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048725 ! cibarial fish-trap bristle development + +[Term] +id: GO:0048719 +name: epistomal sclerite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the epistomal sclerite are generated and organized." [GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048724 ! epistomal sclerite development + +[Term] +id: GO:0048720 +name: posterior cibarial plate morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the posterior cibarial plate are generated and organized." [GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048727 ! posterior cibarial plate development + +[Term] +id: GO:0048721 +name: clypeus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the clypeus are generated and organized." [GOC:rc] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007453 ! clypeo-labral disc morphogenesis +relationship: part_of GO:0048723 ! clypeus development + +[Term] +id: GO:0048722 +name: anterior cibarial plate development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure." [GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048723 +name: clypeus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head." [GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048724 +name: epistomal sclerite development +namespace: biological_process +def: "The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure." [GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048725 +name: cibarial fish-trap bristle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium." [FBbt:00004136, GOC:rc] +synonym: "fish-trap bristle development" EXACT [GOC:rc] +is_a: GO:0022416 ! chaeta development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048726 +name: labrum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure." [GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048727 +name: posterior cibarial plate development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure." [GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048728 +name: proboscis development +namespace: biological_process +alt_id: GO:0016349 +def: "The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure." [GOC:rc] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0035213 ! clypeo-labral disc development + +[Term] +id: GO:0048729 +name: tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0009888 ! tissue development + +[Term] +id: GO:0048730 +name: epidermis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003] +synonym: "hypodermis morphogenesis" RELATED [GOC:kmv, GOC:rk] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0008544 ! epidermis development + +[Term] +id: GO:0048731 +name: system development +namespace: biological_process +def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] +subset: goslim_mouse +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0048732 +name: gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid] +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0048733 +name: sebaceous gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure." [GOC:jid] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0043588 ! skin development + +[Term] +id: GO:0048734 +name: proboscis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head." [GOC:jid, GOC:rc] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048728 ! proboscis development + +[Term] +id: GO:0048735 +name: haltere morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a haltere are generated and organized." [GOC:jid, GOC:rc] +is_a: GO:0035114 ! imaginal disc-derived appendage morphogenesis +is_a: GO:0035120 ! post-embryonic appendage morphogenesis +relationship: part_of GO:0007481 ! haltere disc morphogenesis +relationship: part_of GO:0007482 ! haltere development + +[Term] +id: GO:0048736 +name: appendage development +namespace: biological_process +def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007275 ! multicellular organism development + +[Term] +id: GO:0048737 +name: imaginal disc-derived appendage development +namespace: biological_process +def: "The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism." [GOC:jid, GOC:mtg_sensu, GOC:rc] +is_a: GO:0048736 ! appendage development + +[Term] +id: GO:0048738 +name: cardiac muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] +synonym: "heart muscle development" EXACT [] +is_a: GO:0014706 ! striated muscle tissue development +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0048739 +name: cardiac muscle fiber development +namespace: biological_process +def: "The process whose specific outcome is the progression of cardiac muscle fiber over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] +synonym: "cardiac muscle fibre development" EXACT [] +synonym: "heart muscle fiber development" RELATED [] +is_a: GO:0048747 ! muscle fiber development +is_a: GO:0055013 ! cardiac muscle cell development + +[Term] +id: GO:0048740 +name: obsolete striated muscle fiber development +namespace: biological_process +def: "OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] +comment: This term was made obsolete because it was an unnecessary grouping term. Striated muscle comprises skeletal and cardiac muscle, but GO has opted not to group the muscle fiber development terms. +synonym: "myogenesis" EXACT [] +synonym: "striated muscle fiber development" EXACT [] +synonym: "striated muscle fibre development" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048741 +name: skeletal muscle fiber development +namespace: biological_process +def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle] +synonym: "skeletal muscle fibre development" EXACT [] +synonym: "skeletal myofiber development" EXACT [] +synonym: "skeletal myofibre development" EXACT [] +is_a: GO:0014904 ! myotube cell development +is_a: GO:0048747 ! muscle fiber development +relationship: part_of GO:0007519 ! skeletal muscle tissue development + +[Term] +id: GO:0048742 +name: regulation of skeletal muscle fiber development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm] +synonym: "regulation of skeletal muscle fibre development" EXACT [] +synonym: "regulation of skeletal myofiber development" EXACT [] +synonym: "regulation of skeletal myofibre development" EXACT [] +is_a: GO:0010830 ! regulation of myotube differentiation +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048741 ! skeletal muscle fiber development +relationship: regulates GO:0048741 ! skeletal muscle fiber development + +[Term] +id: GO:0048743 +name: positive regulation of skeletal muscle fiber development +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] +synonym: "activation of skeletal muscle fiber development" NARROW [] +synonym: "positive regulation of skeletal muscle fibre development" EXACT [] +synonym: "positive regulation of skeletal myofiber development" EXACT [] +synonym: "positive regulation of skeletal myofibre development" EXACT [] +synonym: "stimulation of skeletal muscle fiber development" NARROW [] +synonym: "up regulation of skeletal muscle fiber development" EXACT [] +synonym: "up-regulation of skeletal muscle fiber development" EXACT [] +synonym: "upregulation of skeletal muscle fiber development" EXACT [] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0010831 ! positive regulation of myotube differentiation +is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development +is_a: GO:0048742 ! regulation of skeletal muscle fiber development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048741 ! skeletal muscle fiber development +relationship: positively_regulates GO:0048741 ! skeletal muscle fiber development + +[Term] +id: GO:0048744 +name: negative regulation of skeletal muscle fiber development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] +synonym: "down regulation of skeletal muscle fiber development" EXACT [] +synonym: "down-regulation of skeletal muscle fiber development" EXACT [] +synonym: "downregulation of skeletal muscle fiber development" EXACT [] +synonym: "inhibition of skeletal muscle fiber development" NARROW [] +synonym: "negative regulation of skeletal muscle fibre development" EXACT [] +synonym: "negative regulation of skeletal myofiber development" EXACT [] +synonym: "negative regulation of skeletal myofibre development" EXACT [] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0010832 ! negative regulation of myotube differentiation +is_a: GO:0048642 ! negative regulation of skeletal muscle tissue development +is_a: GO:0048742 ! regulation of skeletal muscle fiber development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048741 ! skeletal muscle fiber development +relationship: negatively_regulates GO:0048741 ! skeletal muscle fiber development + +[Term] +id: GO:0048745 +name: smooth muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] +is_a: GO:0060537 ! muscle tissue development + +[Term] +id: GO:0048746 +name: obsolete smooth muscle fiber development +namespace: biological_process +def: "OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] +comment: This term was made obsolete because smooth muscle does not have fibers. +synonym: "smooth muscle fiber development" EXACT [] +synonym: "smooth muscle fibre development" EXACT [] +is_obsolete: true + +[Term] +id: GO:0048747 +name: muscle fiber development +namespace: biological_process +def: "The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] +synonym: "muscle fibre development" EXACT [] +synonym: "myofiber development" EXACT [] +synonym: "myofibre development" EXACT [] +is_a: GO:0055002 ! striated muscle cell development + +[Term] +id: GO:0048749 +name: compound eye development +namespace: biological_process +alt_id: GO:0007456 +def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye] +synonym: "insect-type retina development" EXACT [PMID:11735386] +is_a: GO:0001654 ! eye development + +[Term] +id: GO:0048750 +name: compound eye corneal lens morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the compound eye corneal lens are generated and organized." [GOC:jid] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0001745 ! compound eye morphogenesis +relationship: part_of GO:0048058 ! compound eye corneal lens development + +[Term] +id: GO:0048752 +name: semicircular canal morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the semicircular canals are generated and organized." [GOC:dgh, GOC:dph, GOC:jid] +synonym: "embryonic semicircular canal morphogenesis" EXACT [] +is_a: GO:0035239 ! tube morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042472 ! inner ear morphogenesis +relationship: part_of GO:0060872 ! semicircular canal development + +[Term] +id: GO:0048753 +name: pigment granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc] +subset: goslim_pir +synonym: "pigment granule organisation" EXACT [] +synonym: "pigment granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016050 ! vesicle organization +relationship: part_of GO:0033059 ! cellular pigmentation + +[Term] +id: GO:0048754 +name: branching morphogenesis of an epithelial tube +namespace: biological_process +def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid] +synonym: "tubulogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0035239 ! tube morphogenesis +is_a: GO:0061138 ! morphogenesis of a branching epithelium +relationship: part_of GO:0060562 ! epithelial tube morphogenesis + +[Term] +id: GO:0048755 +name: branching morphogenesis of a nerve +namespace: biological_process +def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid] +is_a: GO:0001763 ! morphogenesis of a branching structure +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0048756 +name: sieve cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials." [GOC:jid, PO:0025415, POC:curators] +is_a: GO:0090603 ! sieve element differentiation +relationship: part_of GO:0010088 ! phloem development + +[Term] +id: GO:0048757 +name: pigment granule maturation +namespace: biological_process +def: "Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state." [GOC:dgh, GOC:jid, GOC:mh] +is_a: GO:0021700 ! developmental maturation +is_a: GO:0043482 ! cellular pigment accumulation +relationship: part_of GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0048758 +name: companion cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member." [CL:0000284, GOC:jid] +is_a: GO:0048760 ! plant parenchymal cell differentiation +relationship: part_of GO:0010088 ! phloem development + +[Term] +id: GO:0048759 +name: xylem vessel member cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened." [GOC:jid, PO:0002003] +synonym: "vessel element cell differentiation" BROAD [] +synonym: "vessel member cell differentiation" BROAD [] +is_a: GO:1905177 ! tracheary element differentiation +relationship: part_of GO:0010089 ! xylem development + +[Term] +id: GO:0048760 +name: plant parenchymal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure." [CL:0000668, GOC:jid, ISBN:069716957X, PO:0005421] +synonym: "parenchymal cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0048761 +name: collenchyma cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles." [CL:0000330, GOC:jid, PO:0000075] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0048762 +name: mesenchymal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0060485 ! mesenchyme development + +[Term] +id: GO:0048763 +name: calcium-induced calcium release activity +namespace: molecular_function +def: "Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration." [GOC:jid, GOC:nln, PMID:2990997, PMID:8381210, PMID:8653752] +is_a: GO:0015278 ! calcium-release channel activity + +[Term] +id: GO:0048764 +name: trichoblast maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state." [GOC:jid] +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0010054 ! trichoblast differentiation + +[Term] +id: GO:0048765 +name: root hair cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a root hair cell." [GOC:jid] +is_a: GO:0010053 ! root epidermal cell differentiation +is_a: GO:0048764 ! trichoblast maturation + +[Term] +id: GO:0048766 +name: root hair initiation +namespace: biological_process +def: "The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth." [GOC:jid, PMID:12468740] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0048765 ! root hair cell differentiation + +[Term] +id: GO:0048767 +name: root hair elongation +namespace: biological_process +def: "The process in which the root hair grows longer." [GOC:jid, PMID:12468740] +is_a: GO:0048588 ! developmental cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0080147 ! root hair cell development + +[Term] +id: GO:0048768 +name: root hair cell tip growth +namespace: biological_process +def: "Localized growth of a plant root hair tip by extension of the cell wall." [GOC:jid, GOC:ki, PMID:12468740] +synonym: "root hair tip growth" EXACT [] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0009932 ! cell tip growth +relationship: part_of GO:0048767 ! root hair elongation + +[Term] +id: GO:0048769 +name: sarcomerogenesis +namespace: biological_process +def: "The process in which sarcomeres are added in series within a fiber." [GOC:jid, GOC:lm, PMID:15947030] +synonym: "myofibril production" EXACT systematic_synonym [] +is_a: GO:0031032 ! actomyosin structure organization +relationship: part_of GO:0030239 ! myofibril assembly + +[Term] +id: GO:0048770 +name: pigment granule +namespace: cellular_component +def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0048771 +name: tissue remodeling +namespace: biological_process +def: "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling." [GOC:ebc] +subset: goslim_pir +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0048772 +name: leucophore differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance." [GOC:jid, GOC:mh] +synonym: "leucophore cell differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0048773 +name: erythrophore differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance." [GOC:jid, GOC:mh] +synonym: "erythrophore cell differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0048774 +name: cyanophore differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes." [GOC:jid, GOC:mh] +synonym: "cyanophore cell differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0048775 +name: regulation of leucophore differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leucophore differentiation." [GOC:mh] +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048772 ! leucophore differentiation +relationship: regulates GO:0048772 ! leucophore differentiation + +[Term] +id: GO:0048776 +name: negative regulation of leucophore differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation." [GOC:mh] +synonym: "down regulation of leucophore differentiation" EXACT [] +synonym: "down-regulation of leucophore differentiation" EXACT [] +synonym: "downregulation of leucophore differentiation" EXACT [] +synonym: "inhibition of leucophore differentiation" NARROW [] +is_a: GO:0048775 ! regulation of leucophore differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048772 ! leucophore differentiation +relationship: negatively_regulates GO:0048772 ! leucophore differentiation + +[Term] +id: GO:0048777 +name: positive regulation of leucophore differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leucophore differentiation." [GOC:mh] +synonym: "activation of leucophore differentiation" NARROW [] +synonym: "stimulation of leucophore differentiation" NARROW [] +synonym: "up regulation of leucophore differentiation" EXACT [] +synonym: "up-regulation of leucophore differentiation" EXACT [] +synonym: "upregulation of leucophore differentiation" EXACT [] +is_a: GO:0048775 ! regulation of leucophore differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048772 ! leucophore differentiation +relationship: positively_regulates GO:0048772 ! leucophore differentiation + +[Term] +id: GO:0048778 +name: regulation of erythrophore differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of erythrophore differentiation." [GOC:mh] +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048773 ! erythrophore differentiation +relationship: regulates GO:0048773 ! erythrophore differentiation + +[Term] +id: GO:0048779 +name: negative regulation of erythrophore differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation." [GOC:mh] +synonym: "down regulation of erythrophore differentiation" EXACT [] +synonym: "down-regulation of erythrophore differentiation" EXACT [] +synonym: "downregulation of erythrophore differentiation" EXACT [] +synonym: "inhibition of erythrophore differentiation" NARROW [] +is_a: GO:0048778 ! regulation of erythrophore differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048773 ! erythrophore differentiation +relationship: negatively_regulates GO:0048773 ! erythrophore differentiation + +[Term] +id: GO:0048780 +name: positive regulation of erythrophore differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of erythrophore differentiation." [GOC:mh] +synonym: "activation of erythrophore differentiation" NARROW [] +synonym: "stimulation of erythrophore differentiation" NARROW [] +synonym: "up regulation of erythrophore differentiation" EXACT [] +synonym: "up-regulation of erythrophore differentiation" EXACT [] +synonym: "upregulation of erythrophore differentiation" EXACT [] +is_a: GO:0048778 ! regulation of erythrophore differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048773 ! erythrophore differentiation +relationship: positively_regulates GO:0048773 ! erythrophore differentiation + +[Term] +id: GO:0048781 +name: regulation of cyanophore differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyanophore differentiation." [GOC:mh] +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048774 ! cyanophore differentiation +relationship: regulates GO:0048774 ! cyanophore differentiation + +[Term] +id: GO:0048782 +name: negative regulation of cyanophore differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation." [GOC:mh] +synonym: "down regulation of cyanophore differentiation" EXACT [] +synonym: "down-regulation of cyanophore differentiation" EXACT [] +synonym: "downregulation of cyanophore differentiation" EXACT [] +synonym: "inhibition of cyanophore differentiation" NARROW [] +is_a: GO:0048781 ! regulation of cyanophore differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048774 ! cyanophore differentiation +relationship: negatively_regulates GO:0048774 ! cyanophore differentiation + +[Term] +id: GO:0048783 +name: positive regulation of cyanophore differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyanophore differentiation." [GOC:mh] +synonym: "activation of cyanophore differentiation" NARROW [] +synonym: "stimulation of cyanophore differentiation" NARROW [] +synonym: "up regulation of cyanophore differentiation" EXACT [] +synonym: "up-regulation of cyanophore differentiation" EXACT [] +synonym: "upregulation of cyanophore differentiation" EXACT [] +is_a: GO:0048781 ! regulation of cyanophore differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048774 ! cyanophore differentiation +relationship: positively_regulates GO:0048774 ! cyanophore differentiation + +[Term] +id: GO:0048784 +name: pigment biosynthetic process involved in pigment granule maturation +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state." [GOC:jid] +synonym: "pigment biosynthetic process during pigment granule maturation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043324 ! pigment metabolic process involved in developmental pigmentation +is_a: GO:0043477 ! pigment biosynthetic process involved in pigment accumulation +intersection_of: GO:0046148 ! pigment biosynthetic process +intersection_of: part_of GO:0048757 ! pigment granule maturation +relationship: part_of GO:0048757 ! pigment granule maturation + +[Term] +id: GO:0048785 +name: hatching gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process." [GOC:bf, GOC:dh, GOC:jid] +is_a: GO:0048732 ! gland development + +[Term] +id: GO:0048786 +name: presynaptic active zone +namespace: cellular_component +def: "A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix." [GOC:dh, GOC:dl, GOC:ef, GOC:jid, GOC:pr, PMID:3152289] +subset: goslim_synapse +synonym: "pre-synaptic active zone" EXACT [] +synonym: "pre-synaptic active zone component" NARROW [NIF_Subcellular:sao1911631652] +synonym: "presynaptic specialization" EXACT [] +xref: NIF_Subcellular:sao792027222 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0048787 +name: presynaptic active zone membrane +namespace: cellular_component +def: "The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters." [PMID:12812759, PMID:12923177, PMID:3152289] +subset: goslim_synapse +synonym: "active zone plasma membrane" EXACT [NIF_Subcellular:sao2038461087] +synonym: "active zone pre-synaptic plasma membrane" EXACT [] +synonym: "active zone presynaptic plasma membrane" EXACT [] +synonym: "pre-synaptic active zone membrane" EXACT [] +xref: NIF_Subcellular:sao2038461087 +is_a: GO:0097060 ! synaptic membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane +intersection_of: part_of GO:0048786 ! presynaptic active zone +relationship: part_of GO:0042734 ! presynaptic membrane +relationship: part_of GO:0048786 ! presynaptic active zone + +[Term] +id: GO:0048788 +name: cytoskeleton of presynaptic active zone +namespace: cellular_component +def: "The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites." [GOC:dh, GOC:dl, GOC:ef, GOC:jid, NIF_Subcellular:sao1470121605, PMID:10944438] +synonym: "active zone cytomatrix" EXACT [] +synonym: "CAZ" NARROW [] +synonym: "pre-synaptic cytoskeletal matrix assembled at active zones" EXACT [] +synonym: "pre-synaptic dense body" NARROW [NIF_Subcellular:sao1111202255, PMID:12575947] +synonym: "pre-synaptic ribbon" RELATED [ISBN:0716723808, NIF_Subcellular:sao1488888179] +synonym: "presynaptic cytomatrix assembled at active zones" EXACT [] +synonym: "presynaptic cytoskeletal matrix" EXACT syngo_official_label [] +synonym: "presynaptic cytoskeletal matrix assembled at active zones" EXACT [] +synonym: "presynaptic dense body" NARROW [PMID:16709774] +synonym: "presynaptic ribbon" RELATED [ISBN:0716723808, NIF_Subcellular:sao1488888179] +synonym: "ribbon" RELATED [NIF_Subcellular:sao1111202255, PMID:12575947] +synonym: "synaptic ribbon" NARROW [PMID:19264728] +synonym: "T-bar" NARROW [PMID:20127822] +synonym: "T-bar ribbon" NARROW [PMID:16384719] +xref: NIF_Subcellular:sao1470121605 +is_a: GO:0030863 ! cortical cytoskeleton +is_a: GO:0099569 ! presynaptic cytoskeleton +intersection_of: GO:0030863 ! cortical cytoskeleton +intersection_of: part_of GO:0098831 ! presynaptic active zone cytoplasmic component +relationship: part_of GO:0098831 ! presynaptic active zone cytoplasmic component + +[Term] +id: GO:0048789 +name: cytoskeletal matrix organization at active zone +namespace: biological_process +def: "The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane." [GOC:dh, GOC:ef, GOC:jid, PMID:12812759] +synonym: "cytoskeletal matrix organisation at active zone" EXACT [GOC:mah] +is_a: GO:0030865 ! cortical cytoskeleton organization + +[Term] +id: GO:0048790 +name: maintenance of presynaptic active zone structure +namespace: biological_process +def: "A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters." [GOC:curators, GOC:dph, GOC:pr] +subset: goslim_synapse +synonym: "maintenance of pre-synaptic active zone structure" EXACT [] +is_a: GO:0099558 ! maintenance of synapse structure +is_a: GO:1990709 ! presynaptic active zone organization + +[Term] +id: GO:0048791 +name: calcium ion-regulated exocytosis of neurotransmitter +namespace: biological_process +def: "The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels." [GOC:curators] +is_a: GO:0016079 ! synaptic vesicle exocytosis +is_a: GO:0017156 ! calcium-ion regulated exocytosis + +[Term] +id: GO:0048792 +name: spontaneous exocytosis of neurotransmitter +namespace: biological_process +def: "The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell." [GOC:curators] +synonym: "spontaneous synaptic vesicle exocytosis" EXACT [] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0048793 +name: pronephros development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151] +synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0001822 ! kidney development + +[Term] +id: GO:0048794 +name: swim bladder development +namespace: biological_process +def: "The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ." [GOC:mh] +synonym: "gas bladder development" EXACT [] +is_a: GO:0048513 ! animal organ development + +[Term] +id: GO:0048795 +name: swim bladder morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ." [GOC:mh] +synonym: "gas bladder morphogenesis" EXACT [] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048794 ! swim bladder development + +[Term] +id: GO:0048796 +name: swim bladder maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ." [GOC:devbiol] +synonym: "gas bladder maturation" EXACT [] +is_a: GO:0048799 ! animal organ maturation +relationship: part_of GO:0048794 ! swim bladder development + +[Term] +id: GO:0048797 +name: swim bladder formation +namespace: biological_process +def: "The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ." [GOC:mh] +synonym: "gas bladder biosynthesis" EXACT [] +synonym: "gas bladder formation" EXACT [] +is_a: GO:0048645 ! animal organ formation +relationship: part_of GO:0048795 ! swim bladder morphogenesis + +[Term] +id: GO:0048798 +name: swim bladder inflation +namespace: biological_process +def: "The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ." [GOC:mh] +synonym: "gas bladder inflation" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048796 ! swim bladder maturation + +[Term] +id: GO:0048799 +name: animal organ maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0048800 +name: antennal morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the antenna are generated and organized." [GOC:jid] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0035107 ! appendage morphogenesis +relationship: part_of GO:0007455 ! eye-antennal disc morphogenesis +relationship: part_of GO:0007469 ! antennal development + +[Term] +id: GO:0048801 +name: antennal joint morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the antennal joint are generated and organized." [GOC:jid] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0048098 ! antennal joint development +relationship: part_of GO:0048800 ! antennal morphogenesis + +[Term] +id: GO:0048802 +name: notum morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the dorsal part of the body are generated and organized." [GOC:jid] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007472 ! wing disc morphogenesis +relationship: part_of GO:0007477 ! notum development + +[Term] +id: GO:0048803 +name: imaginal disc-derived male genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc." [GOC:ai, GOC:sensu] +synonym: "male genital morphogenesis" BROAD [] +is_a: GO:0048805 ! imaginal disc-derived genitalia morphogenesis +is_a: GO:0048808 ! male genitalia morphogenesis +relationship: part_of GO:0007485 ! imaginal disc-derived male genitalia development + +[Term] +id: GO:0048804 +name: imaginal disc-derived female genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of female genitalia are generated and organized from the genital disc." [GOC:ai, GOC:sensu] +synonym: "female genital morphogenesis" BROAD [] +is_a: GO:0048805 ! imaginal disc-derived genitalia morphogenesis +is_a: GO:0048807 ! female genitalia morphogenesis +relationship: part_of GO:0007486 ! imaginal disc-derived female genitalia development + +[Term] +id: GO:0048805 +name: imaginal disc-derived genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc." [GOC:ai, GOC:sensu] +synonym: "genital morphogenesis" BROAD [] +is_a: GO:0035126 ! post-embryonic genitalia morphogenesis +relationship: part_of GO:0007483 ! genital disc morphogenesis +relationship: part_of GO:0007484 ! imaginal disc-derived genitalia development + +[Term] +id: GO:0048806 +name: genitalia development +namespace: biological_process +def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid] +synonym: "genital development" EXACT [] +is_a: GO:0048513 ! animal organ development +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0007548 ! sex differentiation + +[Term] +id: GO:0048807 +name: female genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of female genitalia are generated and organized." [GOC:mah] +synonym: "female genital morphogenesis" RELATED [] +is_a: GO:0035112 ! genitalia morphogenesis +relationship: part_of GO:0030540 ! female genitalia development + +[Term] +id: GO:0048808 +name: male genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888] +synonym: "male genital morphogenesis" RELATED [] +is_a: GO:0035112 ! genitalia morphogenesis +is_a: GO:0090598 ! male anatomical structure morphogenesis +relationship: part_of GO:0030539 ! male genitalia development + +[Term] +id: GO:0048809 +name: analia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster." [GOC:ai, GOC:mtg_sensu] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0007483 ! genital disc morphogenesis +relationship: part_of GO:0007487 ! analia development + +[Term] +id: GO:0048810 +name: female analia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11494318] +is_a: GO:0048809 ! analia morphogenesis +relationship: part_of GO:0045497 ! female analia development + +[Term] +id: GO:0048811 +name: male analia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc." [GOC:mtg_sensu, PMID:11494318] +is_a: GO:0048809 ! analia morphogenesis +relationship: part_of GO:0045496 ! male analia development + +[Term] +id: GO:0048812 +name: neuron projection morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah] +synonym: "neurite biosynthesis" NARROW [] +synonym: "neurite formation" NARROW [] +synonym: "neurite growth" NARROW [] +synonym: "neurite morphogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis +relationship: part_of GO:0031175 ! neuron projection development + +[Term] +id: GO:0048813 +name: dendrite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a dendrite are generated and organized." [GOC:aruk, GOC:bc, GOC:jl, ISBN:0198506732, PMID:22683681] +is_a: GO:0048812 ! neuron projection morphogenesis +relationship: part_of GO:0016358 ! dendrite development +relationship: part_of GO:0048667 ! cell morphogenesis involved in neuron differentiation + +[Term] +id: GO:0048814 +name: regulation of dendrite morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0050773 ! regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048813 ! dendrite morphogenesis +relationship: regulates GO:0048813 ! dendrite morphogenesis + +[Term] +id: GO:0048815 +name: hermaphrodite genitalia morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of hermaphrodite genitalia are generated and organized." [GOC:ems, ISBN:0140512888] +is_a: GO:0035112 ! genitalia morphogenesis +is_a: GO:0035262 ! gonad morphogenesis +relationship: part_of GO:0040035 ! hermaphrodite genitalia development + +[Term] +id: GO:0048816 +name: ocellus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects." [http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0007455 ! eye-antennal disc morphogenesis +relationship: part_of GO:0008056 ! ocellus development + +[Term] +id: GO:0048817 +name: negative regulation of hair follicle maturation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation." [GOC:devbiol] +synonym: "down regulation of hair follicle maturation" EXACT [] +synonym: "down-regulation of hair follicle maturation" EXACT [] +synonym: "downregulation of hair follicle maturation" EXACT [] +synonym: "inhibition of hair follicle maturation" NARROW [] +is_a: GO:0048819 ! regulation of hair follicle maturation +is_a: GO:0051799 ! negative regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048820 ! hair follicle maturation +relationship: negatively_regulates GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0048818 +name: positive regulation of hair follicle maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hair follicle maturation." [GOC:devbiol] +synonym: "activation of hair follicle maturation" NARROW [] +synonym: "stimulation of hair follicle maturation" NARROW [] +synonym: "up regulation of hair follicle maturation" EXACT [] +synonym: "up-regulation of hair follicle maturation" EXACT [] +synonym: "upregulation of hair follicle maturation" EXACT [] +is_a: GO:0048819 ! regulation of hair follicle maturation +is_a: GO:0051798 ! positive regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048820 ! hair follicle maturation +relationship: positively_regulates GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0048819 +name: regulation of hair follicle maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hair follicle maturation." [GOC:devbiol] +is_a: GO:0051797 ! regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048820 ! hair follicle maturation +relationship: regulates GO:0048820 ! hair follicle maturation + +[Term] +id: GO:0048820 +name: hair follicle maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state." [GOC:devbiol] +is_a: GO:0022405 ! hair cycle process +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0001942 ! hair follicle development + +[Term] +id: GO:0048821 +name: erythrocyte development +namespace: biological_process +def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol] +synonym: "RBC development" EXACT [CL:0000232] +synonym: "red blood cell development" EXACT [CL:0000232] +is_a: GO:0061515 ! myeloid cell development +relationship: part_of GO:0030218 ! erythrocyte differentiation + +[Term] +id: GO:0048822 +name: enucleate erythrocyte development +namespace: biological_process +def: "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] +synonym: "enucleate RBC development" EXACT [CL:0000232] +synonym: "enucleate red blood cell development" EXACT [CL:0000232] +is_a: GO:0048821 ! erythrocyte development +relationship: part_of GO:0043353 ! enucleate erythrocyte differentiation + +[Term] +id: GO:0048823 +name: nucleate erythrocyte development +namespace: biological_process +def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] +synonym: "nucleate RBC development" EXACT [CL:0000232] +synonym: "nucleate red blood cell development" EXACT [CL:0000232] +is_a: GO:0048821 ! erythrocyte development +relationship: part_of GO:0043363 ! nucleate erythrocyte differentiation + +[Term] +id: GO:0048824 +name: pigment cell precursor differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor." [GOC:dgh, PMID:16499899] +synonym: "chromatophore precursor differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0048825 +name: cotyledon development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling." [GOC:devbiol, GOC:tb, PO:0020030] +is_a: GO:0009793 ! embryo development ending in seed dormancy +is_a: GO:0048366 ! leaf development + +[Term] +id: GO:0048826 +name: cotyledon morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling." [GOC:devbiol, GOC:tb, PO:0020030] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009965 ! leaf morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0090698 ! post-embryonic plant morphogenesis +relationship: part_of GO:0048825 ! cotyledon development + +[Term] +id: GO:0048827 +name: phyllome development +namespace: biological_process +def: "The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants." [GOC:devbiol, GOC:tb, PO:0006001] +is_a: GO:0099402 ! plant organ development +relationship: part_of GO:0048367 ! shoot system development + +[Term] +id: GO:0048829 +name: root cap development +namespace: biological_process +def: "The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant." [GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048364 ! root development + +[Term] +id: GO:0048830 +name: adventitious root development +namespace: biological_process +def: "The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot." [GOC:tb] +is_a: GO:0048364 ! root development + +[Term] +id: GO:0048831 +name: regulation of shoot system development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shoot development." [GOC:tb, PMID:16361392] +synonym: "regulation of shoot development" EXACT [] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048367 ! shoot system development +relationship: regulates GO:0048367 ! shoot system development + +[Term] +id: GO:0048832 +name: specification of plant organ number +namespace: biological_process +def: "The regionalization process that modulates the quantity of a particular type of plant organ." [GOC:dph, GOC:isa_complete, GOC:tb] +is_a: GO:0003002 ! regionalization +is_a: GO:0050793 ! regulation of developmental process + +[Term] +id: GO:0048833 +name: specification of floral organ number +namespace: biological_process +def: "Any process that modulates the number of floral organs formed in a floral whorl." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048832 ! specification of plant organ number +relationship: part_of GO:0009908 ! flower development + +[Term] +id: GO:0048834 +name: specification of petal number +namespace: biological_process +def: "Any process that modulates the number of petals formed in a flower." [GOC:tb] +is_a: GO:0048833 ! specification of floral organ number +relationship: part_of GO:0048465 ! corolla development + +[Term] +id: GO:0048835 +name: specification of decreased petal number +namespace: biological_process +def: "Any process that reduces the number of petals produced in a developing flower." [GOC:tb] +is_a: GO:0048834 ! specification of petal number + +[Term] +id: GO:0048836 +name: specification of increased petal number +namespace: biological_process +def: "Any process that increases the number of petals produced in a developing flower." [GOC:tb] +is_a: GO:0048834 ! specification of petal number + +[Term] +id: GO:0048837 +name: sorocarp sorus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp." [GOC:devbiol, GOC:mtg_sensu, PMID:4332228] +synonym: "sorocarp sorus formation" EXACT [] +synonym: "sorocarp spore head formation" EXACT [] +synonym: "sorocarp spore head morphogenesis" RELATED [] +is_a: GO:0099120 ! socially cooperative development +relationship: part_of GO:0031154 ! culmination involved in sorocarp development + +[Term] +id: GO:0048838 +name: release of seed from dormancy +namespace: biological_process +def: "The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release." [GOC:dph, GOC:jid, GOC:tb, ISBN:9781405139830] +is_a: GO:0010162 ! seed dormancy process +is_a: GO:0097438 ! exit from dormancy + +[Term] +id: GO:0048839 +name: inner ear development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure." [GOC:sr] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043583 ! ear development + +[Term] +id: GO:0048840 +name: otolith development +namespace: biological_process +def: "The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure." [GOC:sr] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048839 ! inner ear development + +[Term] +id: GO:0048841 +name: regulation of axon extension involved in axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] +is_a: GO:0030516 ! regulation of axon extension +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048846 ! axon extension involved in axon guidance +relationship: regulates GO:0048846 ! axon extension involved in axon guidance + +[Term] +id: GO:0048842 +name: positive regulation of axon extension involved in axon guidance +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] +synonym: "activation of axon extension involved in axon guidance" NARROW [] +synonym: "stimulation of axon extension involved in axon guidance" NARROW [] +synonym: "up regulation of axon extension involved in axon guidance" EXACT [] +synonym: "up-regulation of axon extension involved in axon guidance" EXACT [] +synonym: "upregulation of axon extension involved in axon guidance" EXACT [] +is_a: GO:0045773 ! positive regulation of axon extension +is_a: GO:0048841 ! regulation of axon extension involved in axon guidance +is_a: GO:1902669 ! positive regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048846 ! axon extension involved in axon guidance +relationship: positively_regulates GO:0048846 ! axon extension involved in axon guidance + +[Term] +id: GO:0048843 +name: negative regulation of axon extension involved in axon guidance +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] +synonym: "down regulation of axon extension involved in axon guidance" EXACT [] +synonym: "down-regulation of axon extension involved in axon guidance" EXACT [] +synonym: "downregulation of axon extension involved in axon guidance" EXACT [] +synonym: "inhibition of axon extension involved in axon guidance" NARROW [] +is_a: GO:0030517 ! negative regulation of axon extension +is_a: GO:0048841 ! regulation of axon extension involved in axon guidance +is_a: GO:1902668 ! negative regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048846 ! axon extension involved in axon guidance +relationship: negatively_regulates GO:0048846 ! axon extension involved in axon guidance + +[Term] +id: GO:0048844 +name: artery morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480] +synonym: "arterial morphogenesis" EXACT [] +synonym: "arteriogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0048514 ! blood vessel morphogenesis +relationship: part_of GO:0060840 ! artery development + +[Term] +id: GO:0048845 +name: venous blood vessel morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480] +synonym: "vein morphogenesis" BROAD [] +synonym: "venous morphogenesis" EXACT [] +is_a: GO:0048514 ! blood vessel morphogenesis +relationship: part_of GO:0060841 ! venous blood vessel development + +[Term] +id: GO:0048846 +name: axon extension involved in axon guidance +namespace: biological_process +def: "The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues." [GOC:ef, GOC:jid] +is_a: GO:0048675 ! axon extension +is_a: GO:1902284 ! neuron projection extension involved in neuron projection guidance +intersection_of: GO:0048675 ! axon extension +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance + +[Term] +id: GO:0048847 +name: adenohypophysis formation +namespace: biological_process +def: "The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid] +synonym: "adenophysis biosynthesis" EXACT [] +synonym: "adenophysis formation" EXACT [] +synonym: "anterior pituitary biosynthesis" EXACT [] +synonym: "anterior pituitary formation" EXACT [] +synonym: "anterior pituitary gland biosynthesis" EXACT [] +synonym: "anterior pituitary gland formation" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048855 ! adenohypophysis morphogenesis + +[Term] +id: GO:0048848 +name: neurohypophysis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neurophysis morphogenesis" EXACT [] +synonym: "posterior pituitary gland morphogenesis" EXACT [] +synonym: "posterior pituitary morphogenesis" EXACT [] +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0021985 ! neurohypophysis development +relationship: part_of GO:0048850 ! hypophysis morphogenesis + +[Term] +id: GO:0048849 +name: neurohypophysis formation +namespace: biological_process +def: "The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "neurophysis biosynthesis" EXACT [] +synonym: "neurophysis formation" EXACT [] +synonym: "posterior pituitary biosynthesis" EXACT [] +synonym: "posterior pituitary formation" EXACT [] +synonym: "posterior pituitary gland biosynthesis" EXACT [] +synonym: "posterior pituitary gland formation" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048848 ! neurohypophysis morphogenesis + +[Term] +id: GO:0048850 +name: hypophysis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "pituitary gland morphogenesis" EXACT [] +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0021983 ! pituitary gland development +relationship: part_of GO:0048852 ! diencephalon morphogenesis + +[Term] +id: GO:0048851 +name: hypophysis formation +namespace: biological_process +def: "The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid] +synonym: "hypophysis biosynthesis" EXACT [] +synonym: "pituitary gland biosynthesis" EXACT [] +synonym: "pituitary gland formation" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048850 ! hypophysis morphogenesis + +[Term] +id: GO:0048852 +name: diencephalon morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021536 ! diencephalon development +relationship: part_of GO:0048853 ! forebrain morphogenesis + +[Term] +id: GO:0048853 +name: forebrain morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid] +synonym: "prosencephalon morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0030900 ! forebrain development +relationship: part_of GO:0048854 ! brain morphogenesis + +[Term] +id: GO:0048854 +name: brain morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0007420 ! brain development + +[Term] +id: GO:0048855 +name: adenohypophysis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus." [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid] +synonym: "adenophysis morphogenesis" EXACT [] +synonym: "anterior pituitary gland morphogenesis" EXACT [] +synonym: "anterior pituitary morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021984 ! adenohypophysis development +relationship: part_of GO:0048850 ! hypophysis morphogenesis + +[Term] +id: GO:0048856 +name: anatomical structure development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_plant +synonym: "development of an anatomical structure" EXACT [] +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0048857 +name: neural nucleus development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0048858 +name: cell projection morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021] +is_a: GO:0030030 ! cell projection organization +is_a: GO:0032990 ! cell part morphogenesis +relationship: part_of GO:0000902 ! cell morphogenesis + +[Term] +id: GO:0048859 +name: formation of anatomical boundary +namespace: biological_process +def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis + +[Term] +id: GO:0048860 +name: glioblast division +namespace: biological_process +def: "The process resulting in the physical partitioning and separation of a glioblast into daughter cells." [GOC:devbiol] +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0048861 +name: leukemia inhibitory factor signaling pathway +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:devbiol, GOC:signaling] +synonym: "leukemia inhibitory factor signalling pathway" EXACT [] +is_a: GO:0007167 ! enzyme linked receptor protein signaling pathway + +[Term] +id: GO:0048863 +name: stem cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete] +xref: Wikipedia:Stem_cell_differentiation +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0048864 +name: stem cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0048863 ! stem cell differentiation + +[Term] +id: GO:0048865 +name: stem cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell." [CL:0000034, GOC:isa_complete] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0048863 ! stem cell differentiation + +[Term] +id: GO:0048866 +name: stem cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [CL:0000034, GOC:isa_complete] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0048865 ! stem cell fate commitment + +[Term] +id: GO:0048867 +name: stem cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed." [CL:0000034, GOC:isa_complete] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0048865 ! stem cell fate commitment + +[Term] +id: GO:0048868 +name: pollen tube development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure." [GOC:isa_complete] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0009856 ! pollination + +[Term] +id: GO:0048869 +name: cellular developmental process +namespace: biological_process +def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] +is_a: GO:0009987 ! cellular process +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0048870 +name: cell motility +namespace: biological_process +def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +synonym: "cell locomotion" EXACT [] +synonym: "cell movement" RELATED [] +synonym: "movement of a cell" EXACT [] +is_a: GO:0006928 ! movement of cell or subcellular component +is_a: GO:0040011 ! locomotion +relationship: part_of GO:0051674 ! localization of cell + +[Term] +id: GO:0048871 +name: multicellular organismal homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0048872 +name: homeostasis of number of cells +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete] +synonym: "cell population homeostasis" EXACT [] +synonym: "homeostasis of cell number" EXACT [GOC:dph] +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0048873 +name: homeostasis of number of cells within a tissue +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue." [GOC:isa_complete] +is_a: GO:0001894 ! tissue homeostasis +is_a: GO:0048872 ! homeostasis of number of cells + +[Term] +id: GO:0048874 +name: host-mediated regulation of intestinal microbiota composition +namespace: biological_process +def: "The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut." [PMID:25757720] +synonym: "homeostasis of number of cells in a free-living population" RELATED [] +synonym: "host-induced regulation of intestinal microbiota composition" RELATED [] +is_a: GO:0048872 ! homeostasis of number of cells +is_a: GO:0051851 ! modulation by host of symbiont process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15748 xsd:anyURI + +[Term] +id: GO:0048875 +name: chemical homeostasis within a tissue +namespace: biological_process +def: "Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue." [GOC:isa_complete] +is_a: GO:0001894 ! tissue homeostasis +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0048876 +name: chemical homeostasis within retina +namespace: biological_process +def: "Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina." [GOC:isa_complete] +is_a: GO:0001895 ! retina homeostasis +is_a: GO:0048875 ! chemical homeostasis within a tissue + +[Term] +id: GO:0048877 +name: homeostasis of number of retina cells +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina." [GOC:dph, GOC:isa_complete, GOC:tb] +is_a: GO:0001895 ! retina homeostasis +is_a: GO:0048873 ! homeostasis of number of cells within a tissue + +[Term] +id: GO:0048878 +name: chemical homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of a chemical." [GOC:isa_complete] +subset: goslim_drosophila +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0048880 +name: sensory system development +namespace: biological_process +def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0048881 +name: mechanosensory lateral line system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance." [ISBN:0125296509] +synonym: "LL system development" EXACT [ISBN:0125296509] +is_a: GO:0048925 ! lateral line system development + +[Term] +id: GO:0048882 +name: lateral line development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear." [ISBN:0125296509] +synonym: "LL development" EXACT [] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0048925 ! lateral line system development + +[Term] +id: GO:0048883 +name: neuromast primordium migration +namespace: biological_process +def: "The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop." [PMID:15018940, PMID:15832385] +synonym: "lateral line primordium migration" EXACT [] +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0048882 ! lateral line development + +[Term] +id: GO:0048884 +name: neuromast development +namespace: biological_process +def: "The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals." [ISBN:0125296509] +is_a: GO:0007423 ! sensory organ development +relationship: part_of GO:0048882 ! lateral line development + +[Term] +id: GO:0048885 +name: neuromast deposition +namespace: biological_process +def: "The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line." [PMID:15018940] +is_a: GO:0030336 ! negative regulation of cell migration +relationship: part_of GO:0048884 ! neuromast development + +[Term] +id: GO:0048886 +name: neuromast hair cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons." [CL:0000856, ISBN:0125296509] +is_a: GO:0035315 ! hair cell differentiation +is_a: GO:0042490 ! mechanoreceptor differentiation +relationship: part_of GO:0048884 ! neuromast development + +[Term] +id: GO:0048887 +name: cupula development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter." [ISBN:0125296509] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048884 ! neuromast development + +[Term] +id: GO:0048888 +name: neuromast mantle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded." [ISBN:0125296509] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048884 ! neuromast development + +[Term] +id: GO:0048889 +name: neuromast support cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells." [ISBN:0125296509] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048884 ! neuromast development + +[Term] +id: GO:0048890 +name: lateral line ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear." [ISBN:0125296509, ISBN:0387968377] +synonym: "gLL ganglion development" EXACT [] +is_a: GO:0061550 ! cranial ganglion development +relationship: part_of GO:0007422 ! peripheral nervous system development +relationship: part_of GO:0048925 ! lateral line system development + +[Term] +id: GO:0048891 +name: lateral line ganglion neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron." [PMID:15018940] +synonym: "gLL neuron differentiation" EXACT [] +is_a: GO:0048934 ! peripheral nervous system neuron differentiation +relationship: part_of GO:0048890 ! lateral line ganglion development + +[Term] +id: GO:0048892 +name: lateral line nerve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus." [ISBN:0125296509] +synonym: "nLL development" EXACT [] +is_a: GO:0021545 ! cranial nerve development +relationship: part_of GO:0048925 ! lateral line system development + +[Term] +id: GO:0048893 +name: afferent axon development in lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve." [PMID:15832385] +is_a: GO:0061564 ! axon development +relationship: part_of GO:0048892 ! lateral line nerve development + +[Term] +id: GO:0048894 +name: efferent axon development in a lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve." [PMID:15832385] +is_a: GO:0021955 ! central nervous system neuron axonogenesis +relationship: part_of GO:0048892 ! lateral line nerve development + +[Term] +id: GO:0048895 +name: lateral line nerve glial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve." [PMID:12062041] +is_a: GO:0010001 ! glial cell differentiation +relationship: part_of GO:0048892 ! lateral line nerve development + +[Term] +id: GO:0048896 +name: lateral line nerve glial cell migration +namespace: biological_process +def: "The movement of a glial cell along the axons in a lateral line nerve." [PMID:12062041] +synonym: "glial cell migration in lateral line nerve" EXACT [] +is_a: GO:0008347 ! glial cell migration +relationship: part_of GO:0048892 ! lateral line nerve development + +[Term] +id: GO:0048897 +name: myelination of lateral line nerve axons +namespace: biological_process +def: "The formation of compact myelin sheaths around the axons of a lateral line nerve." [PMID:12112375] +is_a: GO:0042552 ! myelination +relationship: part_of GO:0048938 ! lateral line nerve glial cell morphogenesis involved in differentiation + +[Term] +id: GO:0048898 +name: anterior lateral line system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance." [ISBN:0125296509, PMID:15018940] +synonym: "ALL system development" RELATED [] +is_a: GO:0048925 ! lateral line system development +relationship: part_of GO:0048881 ! mechanosensory lateral line system development + +[Term] +id: GO:0048899 +name: anterior lateral line development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear." [ISBN:0125296509] +synonym: "anterior LL development" EXACT [] +is_a: GO:0048882 ! lateral line development +relationship: part_of GO:0048898 ! anterior lateral line system development + +[Term] +id: GO:0048900 +name: anterior lateral line neuromast primordium migration +namespace: biological_process +def: "The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop." [GOC:dgh, PMID:15832385] +synonym: "ALL neuromast primordium migration" EXACT [] +is_a: GO:0048883 ! neuromast primordium migration +relationship: part_of GO:0048899 ! anterior lateral line development + +[Term] +id: GO:0048901 +name: anterior lateral line neuromast development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals." [ISBN:0125296509] +is_a: GO:0048884 ! neuromast development +relationship: part_of GO:0048899 ! anterior lateral line development + +[Term] +id: GO:0048902 +name: anterior lateral line neuromast deposition +namespace: biological_process +def: "The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line." [PMID:15832385] +is_a: GO:0048885 ! neuromast deposition +relationship: part_of GO:0048901 ! anterior lateral line neuromast development + +[Term] +id: GO:0048903 +name: anterior lateral line neuromast hair cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons." [ISBN:0125296509, ISBN:0387968377] +is_a: GO:0048886 ! neuromast hair cell differentiation +relationship: part_of GO:0048901 ! anterior lateral line neuromast development + +[Term] +id: GO:0048904 +name: anterior lateral line neuromast cupula development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter." [ISBN:0125296509] +is_a: GO:0048887 ! cupula development +relationship: part_of GO:0048901 ! anterior lateral line neuromast development + +[Term] +id: GO:0048905 +name: anterior lateral line neuromast mantle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded." [ISBN:0125296509] +is_a: GO:0048888 ! neuromast mantle cell differentiation +relationship: part_of GO:0048901 ! anterior lateral line neuromast development + +[Term] +id: GO:0048906 +name: anterior lateral line neuromast support cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells." [ISBN:0387968377] +is_a: GO:0048889 ! neuromast support cell differentiation +relationship: part_of GO:0048901 ! anterior lateral line neuromast development + +[Term] +id: GO:0048907 +name: anterior lateral line ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear." [ISBN:0125296509] +synonym: "gALL development" EXACT [] +is_a: GO:0048890 ! lateral line ganglion development +relationship: part_of GO:0048898 ! anterior lateral line system development + +[Term] +id: GO:0048908 +name: anterior lateral line ganglion neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion." [PMID:15018940] +is_a: GO:0048891 ! lateral line ganglion neuron differentiation +relationship: part_of GO:0048907 ! anterior lateral line ganglion development + +[Term] +id: GO:0048909 +name: anterior lateral line nerve development +namespace: biological_process +alt_id: GO:0021734 +def: "The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0125296509] +synonym: "ALLN development" EXACT [] +synonym: "nALL development" EXACT [] +synonym: "rostral lateral line nerve development" EXACT [] +is_a: GO:0048892 ! lateral line nerve development +relationship: part_of GO:0048898 ! anterior lateral line system development + +[Term] +id: GO:0048910 +name: afferent axon development in anterior lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve." [PMID:15018940] +is_a: GO:0048893 ! afferent axon development in lateral line nerve +relationship: part_of GO:0048909 ! anterior lateral line nerve development + +[Term] +id: GO:0048911 +name: efferent axon development in anterior lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve." [PMID:15018940] +is_a: GO:0048894 ! efferent axon development in a lateral line nerve +relationship: part_of GO:0048909 ! anterior lateral line nerve development + +[Term] +id: GO:0048912 +name: glial cell migration in anterior lateral line nerve +namespace: biological_process +def: "The movement of a glial cell along the axons in the anterior lateral line nerve." [PMID:12062041] +is_a: GO:0048896 ! lateral line nerve glial cell migration +relationship: part_of GO:0048909 ! anterior lateral line nerve development + +[Term] +id: GO:0048913 +name: anterior lateral line nerve glial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve." [PMID:15832385] +is_a: GO:0048895 ! lateral line nerve glial cell differentiation +relationship: part_of GO:0048909 ! anterior lateral line nerve development + +[Term] +id: GO:0048914 +name: myelination of anterior lateral line nerve axons +namespace: biological_process +def: "The formation of compact myelin sheaths around the axons of the anterior lateral line nerve." [PMID:12112375] +is_a: GO:0048897 ! myelination of lateral line nerve axons +relationship: part_of GO:0048940 ! anterior lateral line nerve glial cell morphogenesis involved in differentiation + +[Term] +id: GO:0048915 +name: posterior lateral line system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance." [ISBN:0125296509, PMID:15018940] +synonym: "PLL" RELATED [] +is_a: GO:0048925 ! lateral line system development +relationship: part_of GO:0048881 ! mechanosensory lateral line system development + +[Term] +id: GO:0048916 +name: posterior lateral line development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear." [ISBN:0125296509] +synonym: "PLL development" EXACT [] +is_a: GO:0048882 ! lateral line development +relationship: part_of GO:0048915 ! posterior lateral line system development + +[Term] +id: GO:0048917 +name: posterior lateral line ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear." [ISBN:0125296509, ISBN:0387968377] +synonym: "gPLL development" EXACT [] +is_a: GO:0048890 ! lateral line ganglion development +relationship: part_of GO:0048915 ! posterior lateral line system development + +[Term] +id: GO:0048918 +name: posterior lateral line nerve development +namespace: biological_process +alt_id: GO:0021733 +def: "The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0125296509] +synonym: "caudal lateral line nerve development" EXACT [] +synonym: "PLLN development" EXACT [] +is_a: GO:0048892 ! lateral line nerve development +relationship: part_of GO:0048915 ! posterior lateral line system development + +[Term] +id: GO:0048919 +name: posterior lateral line neuromast development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals." [ISBN:0125296509] +is_a: GO:0048884 ! neuromast development +relationship: part_of GO:0048916 ! posterior lateral line development + +[Term] +id: GO:0048920 +name: posterior lateral line neuromast primordium migration +namespace: biological_process +def: "The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop." [GOC:dgh, PMID:15832385] +synonym: "PLL neuromast primordium migration" EXACT [] +is_a: GO:0048883 ! neuromast primordium migration +relationship: part_of GO:0048916 ! posterior lateral line development + +[Term] +id: GO:0048921 +name: posterior lateral line neuromast cupula development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter." [ISBN:0125296509] +is_a: GO:0048887 ! cupula development +relationship: part_of GO:0048919 ! posterior lateral line neuromast development + +[Term] +id: GO:0048922 +name: posterior lateral line neuromast deposition +namespace: biological_process +def: "The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line." [PMID:15832385] +is_a: GO:0048885 ! neuromast deposition +relationship: part_of GO:0048919 ! posterior lateral line neuromast development + +[Term] +id: GO:0048923 +name: posterior lateral line neuromast hair cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons." [ISBN:0125296509] +is_a: GO:0048886 ! neuromast hair cell differentiation +relationship: part_of GO:0048919 ! posterior lateral line neuromast development + +[Term] +id: GO:0048924 +name: posterior lateral line neuromast mantle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded." [ISBN:0125296509] +is_a: GO:0048888 ! neuromast mantle cell differentiation +relationship: part_of GO:0048919 ! posterior lateral line neuromast development + +[Term] +id: GO:0048925 +name: lateral line system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear." [GOC:dgh, ISBN:0125296509] +is_a: GO:0048880 ! sensory system development + +[Term] +id: GO:0048926 +name: electrosensory lateral line system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure." [GOC:dgh] +is_a: GO:0048925 ! lateral line system development + +[Term] +id: GO:0048927 +name: posterior lateral line neuromast support cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells." [ISBN:0387968377] +is_a: GO:0048889 ! neuromast support cell differentiation +relationship: part_of GO:0048919 ! posterior lateral line neuromast development + +[Term] +id: GO:0048928 +name: posterior lateral line ganglion neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion." [PMID:15018940] +is_a: GO:0048891 ! lateral line ganglion neuron differentiation +relationship: part_of GO:0048917 ! posterior lateral line ganglion development + +[Term] +id: GO:0048929 +name: efferent axon development in posterior lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve." [PMID:15018940] +is_a: GO:0048894 ! efferent axon development in a lateral line nerve +relationship: part_of GO:0048918 ! posterior lateral line nerve development + +[Term] +id: GO:0048930 +name: glial cell migration in posterior lateral line nerve +namespace: biological_process +def: "The movement of a glial cell along the axons in the posterior lateral line nerve." [PMID:12062041] +is_a: GO:0048896 ! lateral line nerve glial cell migration +relationship: part_of GO:0048918 ! posterior lateral line nerve development + +[Term] +id: GO:0048931 +name: posterior lateral line nerve glial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve." [PMID:15832385] +is_a: GO:0048895 ! lateral line nerve glial cell differentiation +relationship: part_of GO:0048918 ! posterior lateral line nerve development + +[Term] +id: GO:0048932 +name: myelination of posterior lateral line nerve axons +namespace: biological_process +def: "The formation of compact myelin sheaths around the axons of the posterior lateral line nerve." [PMID:12112375] +is_a: GO:0048897 ! myelination of lateral line nerve axons +relationship: part_of GO:0048942 ! posterior lateral line nerve glial cell morphogenesis involved in differentiation + +[Term] +id: GO:0048933 +name: afferent axon development in posterior lateral line nerve +namespace: biological_process +def: "The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve." [PMID:15018940] +is_a: GO:0048893 ! afferent axon development in lateral line nerve +relationship: part_of GO:0048918 ! posterior lateral line nerve development + +[Term] +id: GO:0048934 +name: peripheral nervous system neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh] +is_a: GO:0030182 ! neuron differentiation +relationship: part_of GO:0007422 ! peripheral nervous system development + +[Term] +id: GO:0048935 +name: peripheral nervous system neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0048934 ! peripheral nervous system neuron differentiation + +[Term] +id: GO:0048936 +name: peripheral nervous system neuron axonogenesis +namespace: biological_process +def: "Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells." [GOC:dgh] +is_a: GO:0007409 ! axonogenesis +relationship: part_of GO:0048935 ! peripheral nervous system neuron development + +[Term] +id: GO:0048937 +name: lateral line nerve glial cell development +namespace: biological_process +def: "The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dgh] +is_a: GO:0021782 ! glial cell development +relationship: part_of GO:0048895 ! lateral line nerve glial cell differentiation + +[Term] +id: GO:0048938 +name: lateral line nerve glial cell morphogenesis involved in differentiation +namespace: biological_process +def: "The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve." [GOC:dgh] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: part_of GO:0048937 ! lateral line nerve glial cell development +relationship: part_of GO:0048937 ! lateral line nerve glial cell development + +[Term] +id: GO:0048939 +name: anterior lateral line nerve glial cell development +namespace: biological_process +def: "The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dgh] +is_a: GO:0048937 ! lateral line nerve glial cell development +relationship: part_of GO:0048913 ! anterior lateral line nerve glial cell differentiation + +[Term] +id: GO:0048940 +name: anterior lateral line nerve glial cell morphogenesis involved in differentiation +namespace: biological_process +def: "The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve." [GOC:dgh] +is_a: GO:0048938 ! lateral line nerve glial cell morphogenesis involved in differentiation +intersection_of: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: part_of GO:0048939 ! anterior lateral line nerve glial cell development +relationship: part_of GO:0048939 ! anterior lateral line nerve glial cell development + +[Term] +id: GO:0048941 +name: posterior lateral line nerve glial cell development +namespace: biological_process +def: "The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dgh] +is_a: GO:0048937 ! lateral line nerve glial cell development +relationship: part_of GO:0048931 ! posterior lateral line nerve glial cell differentiation + +[Term] +id: GO:0048942 +name: posterior lateral line nerve glial cell morphogenesis involved in differentiation +namespace: biological_process +def: "The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve." [GOC:dgh] +is_a: GO:0048938 ! lateral line nerve glial cell morphogenesis involved in differentiation +intersection_of: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: part_of GO:0048941 ! posterior lateral line nerve glial cell development +relationship: part_of GO:0048941 ! posterior lateral line nerve glial cell development + +[Term] +id: GO:0050000 +name: chromosome localization +namespace: biological_process +def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai] +synonym: "chromosome localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of chromosome localization" EXACT [] +synonym: "establishment and maintenance of chromosome position" EXACT [] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0050001 +name: D-glutaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate." [EC:3.5.1.35, MetaCyc:D-GLUTAMINASE-RXN] +synonym: "D-glutamine amidohydrolase activity" EXACT [EC:3.5.1.35] +xref: EC:3.5.1.35 +xref: MetaCyc:D-GLUTAMINASE-RXN +xref: RHEA:22840 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050002 +name: D-proline reductase (dithiol) activity +namespace: molecular_function +def: "Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline." [EC:1.21.4.1, MetaCyc:D-PROLINE-REDUCTASE-(DITHIOL)-RXN] +comment: Note that this function was formerly EC:1.4.4.1. +synonym: "5-aminopentanoate:lipoate oxidoreductase (cyclizing)" EXACT [EC:1.21.4.1] +xref: EC:1.21.4.1 +xref: MetaCyc:1.21.4.1-RXN +xref: RHEA:12737 +is_a: GO:0050485 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor + +[Term] +id: GO:0050003 +name: deoxycytidylate C-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate." [EC:2.1.1.54, RHEA:11568] +synonym: "5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity" EXACT [EC:2.1.1.54] +synonym: "dCMP methyltransferase activity" EXACT [EC:2.1.1.54] +synonym: "deoxycytidylate methyltransferase activity" EXACT [EC:2.1.1.54] +xref: EC:2.1.1.54 +xref: KEGG_REACTION:R01670 +xref: MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN +xref: RHEA:11568 +is_a: GO:0008169 ! C-methyltransferase activity + +[Term] +id: GO:0050004 +name: isoflavone 7-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside." [EC:2.4.1.170, MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN] +synonym: "UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.170] +synonym: "UDPglucose-flavonoid 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] +synonym: "UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.170] +synonym: "UDPglucose:isoflavone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] +synonym: "uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] +xref: EC:2.4.1.170 +xref: MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050005 +name: isohexenylglutaconyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O." [EC:4.2.1.57, RHEA:24144] +synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]" RELATED [EC:4.2.1.57] +synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity" EXACT [EC:4.2.1.57] +synonym: "3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity" EXACT [EC:4.2.1.57] +synonym: "beta-isohexenylglutaconyl-CoA-hydratase activity" EXACT [EC:4.2.1.57] +synonym: "isohexenylglutaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.57] +xref: EC:4.2.1.57 +xref: KEGG_REACTION:R03493 +xref: MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN +xref: RHEA:24144 +xref: UM-BBD_reactionID:r1167 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050006 +name: isomaltulose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose." [EC:5.4.99.11, MetaCyc:ISOMALTULOSE-SYNTHASE-RXN] +synonym: "isomaltulose synthetase activity" EXACT [EC:5.4.99.11] +synonym: "sucrose alpha-glucosyltransferase activity" EXACT [EC:5.4.99.11] +synonym: "sucrose glucosylmutase activity" EXACT [EC:5.4.99.11] +synonym: "trehalulose synthase activity" EXACT [EC:5.4.99.11] +xref: EC:5.4.99.11 +xref: MetaCyc:ISOMALTULOSE-SYNTHASE-RXN +xref: RHEA:24032 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0050007 +name: isonocardicin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A." [EC:2.5.1.38, RHEA:19845] +synonym: "nocardicin aminocarboxypropyltransferase activity" EXACT [EC:2.5.1.38] +synonym: "S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.38] +xref: EC:2.5.1.38 +xref: KEGG_REACTION:R03072 +xref: MetaCyc:ISONOCARDICIN-SYNTHASE-RXN +xref: RHEA:19845 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050008 +name: isopiperitenone delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: isopiperitenone = piperitenone." [EC:5.3.3.11, RHEA:21516] +synonym: "isopiperitenone D-isomerase activity" EXACT [] +synonym: "isopiperitenone delta8-delta4-isomerase activity" EXACT [EC:5.3.3.11] +xref: EC:5.3.3.11 +xref: KEGG_REACTION:R03782 +xref: MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN +xref: RHEA:21516 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0050009 +name: isopropanol dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH." [EC:1.1.1.80, RHEA:21792] +synonym: "propan-2-ol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.80] +xref: EC:1.1.1.80 +xref: KEGG_REACTION:R01550 +xref: MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN +xref: RHEA:21792 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050010 +name: isovitexin beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP." [EC:2.4.1.106, RHEA:19529] +synonym: "isovitexin b-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.106] +synonym: "UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.106] +synonym: "uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity" EXACT [EC:2.4.1.106] +xref: EC:2.4.1.106 +xref: KEGG_REACTION:R03686 +xref: MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:19529 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050011 +name: itaconyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O." [EC:4.2.1.56, MetaCyc:ITACONYL-COA-HYDRATASE-RXN] +synonym: "citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)" EXACT [EC:4.2.1.56] +synonym: "citramalyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.56] +synonym: "itaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.56] +xref: EC:4.2.1.56 +xref: MetaCyc:ITACONYL-COA-HYDRATASE-RXN +xref: RHEA:13785 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050012 +name: juglone 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-naphthoquinone + A + H(2)O + H(+)." [EC:1.14.99.27, RHEA:18745] +synonym: "5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.99.27] +synonym: "juglone hydroxylase activity" EXACT [] +synonym: "naphthoquinone hydroxylase activity" EXACT [EC:1.14.99.27] +synonym: "naphthoquinone-hydroxylase activity" EXACT [EC:1.14.99.27] +xref: EC:1.14.99.27 +xref: KEGG_REACTION:R04327 +xref: MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN +xref: RHEA:18745 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050013 +name: 2-dehydropantoate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde." [EC:4.1.2.12, MetaCyc:KETOPANTOALDOLASE-RXN] +synonym: "2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)" EXACT [EC:4.1.2.12] +synonym: "2-dehydropantoate formaldehyde-lyase activity" EXACT [EC:4.1.2.12] +synonym: "ketopantoaldolase activity" EXACT [] +xref: EC:4.1.2.12 +xref: MetaCyc:KETOPANTOALDOLASE-RXN +xref: RHEA:23276 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050014 +name: ketotetrose-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate." [EC:4.1.2.2, RHEA:20932] +synonym: "erythrose-1-phosphate synthase activity" EXACT [EC:4.1.2.2] +synonym: "erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.2] +synonym: "erythrulose-1-phosphate formaldehyde-lyase activity" EXACT [EC:4.1.2.2] +synonym: "erythrulose-1-phosphate synthetase activity" EXACT [EC:4.1.2.2] +synonym: "phosphoketotetrose aldolase activity" EXACT [EC:4.1.2.2] +xref: EC:4.1.2.2 +xref: KEGG_REACTION:R01014 +xref: MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN +xref: RHEA:20932 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050015 +name: kievitone hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone." [EC:4.2.1.95, RHEA:23604] +synonym: "KHase activity" EXACT [EC:4.2.1.95] +synonym: "kievitone-hydrate hydro-lyase (kievitone-forming)" EXACT [EC:4.2.1.95] +synonym: "kievitone-hydrate hydro-lyase activity" EXACT [EC:4.2.1.95] +xref: EC:4.2.1.95 +xref: KEGG_REACTION:R03622 +xref: MetaCyc:KIEVITONE-HYDRATASE-RXN +xref: RHEA:23604 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050016 +name: kynurenine 7,8-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor." [EC:1.14.99.2, MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN] +synonym: "kynurenate 7,8-hydroxylase activity" EXACT [EC:1.14.99.2] +synonym: "kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.99.2] +synonym: "kynurenic acid hydroxylase activity" EXACT [EC:1.14.99.2] +synonym: "kynurenic hydroxylase activity" EXACT [EC:1.14.99.2] +xref: EC:1.14.99.2 +xref: MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN +xref: RHEA:11968 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050017 +name: L-3-cyanoalanine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine." [EC:4.4.1.9, MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN] +synonym: "beta-cyano-L-alanine synthase activity" EXACT [EC:4.4.1.9] +synonym: "beta-cyanoalanine synthase activity" EXACT [EC:4.4.1.9] +synonym: "beta-cyanoalanine synthetase activity" EXACT [EC:4.4.1.9] +synonym: "L-cysteine hydrogen-sulfide-lyase (adding HCN)" EXACT [EC:4.4.1.9] +synonym: "L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)" EXACT [EC:4.4.1.9] +xref: EC:4.4.1.9 +xref: MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN +xref: RHEA:17821 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0050018 +name: L-amino-acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH." [EC:1.4.1.5, MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN] +synonym: "L-amino-acid:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.5] +xref: EC:1.4.1.5 +xref: MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN +xref: RHEA:10396 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050019 +name: L-arabinitol 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH." [EC:1.1.1.12, RHEA:16381] +xref: EC:1.1.1.12 +xref: KEGG_REACTION:R01903 +xref: MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN +xref: RHEA:16381 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050020 +name: L-arabinonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O." [EC:4.2.1.25, RHEA:20968] +synonym: "L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)" EXACT [EC:4.2.1.25] +synonym: "L-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.25] +synonym: "L-arabonate dehydrase activity" EXACT [EC:4.2.1.25] +synonym: "L-arabonate dehydratase activity" EXACT [EC:4.2.1.25] +xref: EC:4.2.1.25 +xref: KEGG_REACTION:R02522 +xref: MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN +xref: RHEA:20968 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050021 +name: L-arabinonolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+)." [EC:3.1.1.15, RHEA:16217] +synonym: "L-arabinono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.15] +xref: EC:3.1.1.15 +xref: KEGG_REACTION:R02526 +xref: MetaCyc:L-ARABINONOLACTONASE-RXN +xref: RHEA:16217 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050022 +name: L-arabinose 1-dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH." [EC:1.1.1.46, MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN] +synonym: "L-arabinose 1-dehydrogenase activity" BROAD [] +synonym: "L-arabinose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.46] +xref: EC:1.1.1.46 +xref: MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN +xref: RHEA:17925 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050023 +name: L-fuconate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O." [EC:4.2.1.68, RHEA:22772] +synonym: "L-fuconate hydratase activity" EXACT [] +synonym: "L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)" EXACT [EC:4.2.1.68] +synonym: "L-fuconate hydro-lyase activity" EXACT [EC:4.2.1.68] +xref: EC:4.2.1.68 +xref: KEGG_REACTION:R03688 +xref: MetaCyc:L-FUCONATE-HYDRATASE-RXN +xref: RHEA:22772 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050024 +name: L-galactonolactone oxidase activity +namespace: molecular_function +alt_id: GO:0033733 +def: "Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+)." [EC:1.3.3.12, RHEA:20617] +synonym: "L-galactono-1,4-lactone oxidase activity" EXACT [EC:1.3.3.12] +synonym: "L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity" EXACT [EC:1.3.3.12] +synonym: "L-xylono-1,4-lactone oxidase activity" EXACT [EC:1.3.3.12] +xref: EC:1.3.3.12 +xref: KEGG_REACTION:R00643 +xref: MetaCyc:1.3.3.12-RXN +xref: RHEA:20617 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050025 +name: L-glutamate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2." [EC:1.4.3.11, MetaCyc:L-GLUTAMATE-OXIDASE-RXN] +synonym: "glutamate (acceptor) dehydrogenase activity" EXACT [EC:1.4.3.11] +synonym: "glutamate oxidase activity" EXACT [EC:1.4.3.11] +synonym: "glutamic acid oxidase activity" EXACT [EC:1.4.3.11] +synonym: "glutamic dehydrogenase (acceptor)" EXACT [EC:1.4.3.11] +synonym: "L-glutamate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.11] +synonym: "L-glutamic acid oxidase activity" EXACT [EC:1.4.3.11] +xref: EC:1.4.3.11 +xref: MetaCyc:L-GLUTAMATE-OXIDASE-RXN +xref: RHEA:20728 +is_a: GO:0001716 ! L-amino-acid oxidase activity + +[Term] +id: GO:0050026 +name: L-glycol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+." [EC:1.1.1.185, MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN] +synonym: "glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity" EXACT [EC:1.1.1.185] +synonym: "L-(+)-glycol:NAD(P) oxidoreductase activity" EXACT [EC:1.1.1.185] +synonym: "L-glycol:NAD(P) dehydrogenase activity" EXACT [EC:1.1.1.185] +synonym: "L-glycol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.185] +xref: EC:1.1.1.185 +xref: MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050027 +name: obsolete L-idonate 2-dehydrogenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH." [MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN] +comment: This term was made obsolete because EC:1.1.1.128 was deleted: the reaction described is covered by EC:1.1.1.264. +synonym: "5-keto-D-gluconate 2-reductase activity" EXACT [EC:1.1.1.128] +synonym: "5-ketogluconate 2-reductase activity" EXACT [EC:1.1.1.128] +synonym: "5-ketoglucono-idono-reductase activity" EXACT [EC:1.1.1.128] +synonym: "5KGR" RELATED [EC:1.1.1.128] +synonym: "L-idonate 2-dehydrogenase activity" EXACT [] +synonym: "L-idonate dehydrogenase activity" EXACT [EC:1.1.1.128] +synonym: "L-idonate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.128] +synonym: "reductase, 5-ketogluconate 5- (L-idonate-forming)" EXACT [EC:1.1.1.128] +xref: EC:1.1.1.128 +xref: MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN +xref: RHEA:21176 +is_obsolete: true +consider: GO:0050572 + +[Term] +id: GO:0050028 +name: L-lysine-lactamase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine." [EC:3.5.2.11, RHEA:21388] +synonym: "L-alpha-aminocaprolactam hydrolase activity" EXACT [EC:3.5.2.11] +synonym: "L-lysinamidase activity" EXACT [EC:3.5.2.11] +synonym: "L-lysine-1,6-lactam lactamhydrolase activity" EXACT [EC:3.5.2.11] +xref: EC:3.5.2.11 +xref: KEGG_REACTION:R00463 +xref: MetaCyc:L-LYSINE-LACTAMASE-RXN +xref: RHEA:21388 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0050029 +name: L-lysine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+)." [EC:1.4.3.14, RHEA:14437] +synonym: "L-lysine alpha-oxidase activity" EXACT [EC:1.4.3.14] +synonym: "L-lysine:oxygen 2-oxidoreductase (deaminating)" EXACT [EC:1.4.3.14] +synonym: "L-lysyl-alpha-oxidase activity" EXACT [EC:1.4.3.14] +xref: EC:1.4.3.14 +xref: KEGG_REACTION:R00447 +xref: MetaCyc:L-LYSINE-OXIDASE-RXN +xref: MetaCyc:PWY-5311 +xref: RHEA:14437 +is_a: GO:0001716 ! L-amino-acid oxidase activity + +[Term] +id: GO:0050030 +name: L-pipecolate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate." [EC:1.5.99.3, MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN] +synonym: "L-pipecolate:(acceptor) 1,6-oxidoreductase activity" EXACT [EC:1.5.99.3] +synonym: "L-pipecolate:acceptor 1,6-oxidoreductase activity" EXACT [EC:1.5.99.3] +xref: EC:1.5.99.3 +xref: MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN +xref: RHEA:19777 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0050031 +name: L-pipecolate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate." [EC:1.5.3.7, RHEA:11992] +synonym: "L-pipecolate:oxygen 1,6-oxidoreductase activity" EXACT [EC:1.5.3.7] +synonym: "L-pipecolic acid oxidase activity" EXACT [EC:1.5.3.7] +xref: EC:1.5.3.7 +xref: KEGG_REACTION:R02204 +xref: MetaCyc:L-PIPECOLATE-OXIDASE-RXN +xref: Reactome:R-HSA-6783880 "PIPOX oxidises PPCA to P6C" +xref: RHEA:11992 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0050032 +name: L-rhamnonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O." [EC:4.2.1.90, RHEA:23080] +synonym: "L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)" EXACT [EC:4.2.1.90] +synonym: "L-rhamnonate hydro-lyase activity" EXACT [EC:4.2.1.90] +xref: EC:4.2.1.90 +xref: KEGG_REACTION:R03774 +xref: MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN +xref: RHEA:23080 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050033 +name: L-rhamnono-1,4-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+)." [EC:3.1.1.65, RHEA:10288] +synonym: "L-rhamno-gamma-lactonase activity" EXACT [EC:3.1.1.65] +synonym: "L-rhamnono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.65] +synonym: "L-rhamnono-gamma-lactonase activity" EXACT [EC:3.1.1.65] +xref: EC:3.1.1.65 +xref: KEGG_REACTION:R03772 +xref: MetaCyc:L-RHAMNONO-14-LACTONASE-RXN +xref: RHEA:10288 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050034 +name: L-rhamnose 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH." [EC:1.1.1.173, RHEA:12649] +synonym: "L-rhamnofuranose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.173] +xref: EC:1.1.1.173 +xref: KEGG_REACTION:R03942 +xref: MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN +xref: RHEA:12649 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050035 +name: L-sorbose oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2)." [EC:1.1.3.11, RHEA:17853] +synonym: "L-sorbose:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.11] +xref: EC:1.1.3.11 +xref: KEGG_REACTION:R01695 +xref: MetaCyc:L-SORBOSE-OXIDASE-RXN +xref: RHEA:17853 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050036 +name: L-threonate 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH." [EC:1.1.1.129, RHEA:23376] +synonym: "L-threonate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.129] +synonym: "L-threonic acid dehydrogenase activity" EXACT [EC:1.1.1.129] +synonym: "threonate dehydrogenase activity" EXACT [EC:1.1.1.129] +xref: EC:1.1.1.129 +xref: KEGG_REACTION:R03733 +xref: MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN +xref: RHEA:23376 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050037 +name: L-xylose 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH." [EC:1.1.1.113, RHEA:15789] +synonym: "L-xylose dehydrogenase activity" EXACT [EC:1.1.1.113] +synonym: "L-xylose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.113] +synonym: "NADPH-xylose reductase activity" EXACT [EC:1.1.1.113] +xref: EC:1.1.1.113 +xref: KEGG_REACTION:R03586 +xref: MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN +xref: RHEA:15789 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050038 +name: L-xylulose reductase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH." [EC:1.1.1.10, RHEA:17025] +synonym: "L-xylulose reductase activity" BROAD [] +xref: EC:1.1.1.10 +xref: KEGG_REACTION:R01904 +xref: MetaCyc:L-XYLULOSE-REDUCTASE-RXN +xref: Reactome:R-HSA-5661240 "DCXR tetramer reduces L-xylulose to xylitol" +xref: Reactome:R-HSA-5662851 "Defective DCXR does not reduce L-xylulose to xylitol" +xref: RHEA:17025 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050039 +name: lactaldehyde reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH." [EC:1.1.1.55, RHEA:15885] +synonym: "1,2-propanediol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.55] +synonym: "lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.55] +synonym: "NADP-1,2-propanediol dehydrogenase activity" EXACT [EC:1.1.1.55] +synonym: "propane-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.55] +synonym: "propanediol dehydrogenase activity" EXACT [EC:1.1.1.55] +xref: EC:1.1.1.55 +xref: KEGG_REACTION:R02259 +xref: MetaCyc:LACTALDEHYDE-REDUCTASE-NADPH-RXN +xref: RHEA:15885 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050040 +name: lactate 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O." [EC:1.13.12.4, RHEA:16513] +synonym: "(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.4] +synonym: "L-lactate monooxygenase activity" EXACT [EC:1.13.12.4] +synonym: "L-lactate-2-monooxygenase activity" EXACT [EC:1.13.12.4] +synonym: "lactate monooxygenase activity" EXACT [EC:1.13.12.4] +synonym: "lactate oxidase activity" EXACT [EC:1.13.12.4] +synonym: "lactate oxidative decarboxylase activity" EXACT [EC:1.13.12.4] +synonym: "lactate oxygenase activity" EXACT [EC:1.13.12.4] +synonym: "lactic oxidase activity" EXACT [EC:1.13.12.4] +synonym: "lactic oxygenase activity" EXACT [EC:1.13.12.4] +xref: EC:1.13.12.4 +xref: KEGG_REACTION:R00319 +xref: MetaCyc:LACTATE-2-MONOOXYGENASE-RXN +xref: RHEA:16513 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0050041 +name: lactate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate = acetaldehyde + formate." [EC:4.1.2.36, RHEA:17909] +synonym: "(S)-lactate acetaldehyde-lyase (formate-forming)" EXACT [EC:4.1.2.36] +synonym: "(S)-lactate acetaldehyde-lyase activity" EXACT [EC:4.1.2.36] +synonym: "lactate synthase activity" EXACT [EC:4.1.2.36] +xref: EC:4.1.2.36 +xref: KEGG_REACTION:R00753 +xref: MetaCyc:LACTATE-ALDOLASE-RXN +xref: RHEA:17909 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050042 +name: lactate-malate transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate." [EC:1.1.99.7, RHEA:10984] +synonym: "(S)-lactate:oxaloacetate oxidoreductase activity" EXACT [EC:1.1.99.7] +synonym: "malate-lactate transhydrogenase activity" EXACT [EC:1.1.99.7] +xref: EC:1.1.99.7 +xref: KEGG_REACTION:R01447 +xref: MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN +xref: RHEA:10984 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0050043 +name: lactate racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-lactate = (R)-lactate." [EC:5.1.2.1, RHEA:10960] +synonym: "hydroxyacid racemase activity" EXACT [EC:5.1.2.1] +synonym: "lactic acid racemase activity" EXACT [EC:5.1.2.1] +synonym: "lacticoracemase activity" EXACT [EC:5.1.2.1] +xref: EC:5.1.2.1 +xref: KEGG_REACTION:R01450 +xref: MetaCyc:LACTATE-RACEMASE-RXN +xref: RHEA:10960 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0050044 +name: galactose-6-phosphate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate." [EC:5.3.1.26, RHEA:13033] +synonym: "D-galactose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.26] +synonym: "D-galactose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.26] +xref: EC:5.3.1.26 +xref: KEGG_REACTION:R03240 +xref: MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN +xref: RHEA:13033 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0050045 +name: laminaribiose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate." [EC:2.4.1.31, MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN] +synonym: "3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.31] +xref: EC:2.4.1.31 +xref: MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN +xref: RHEA:16617 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050046 +name: lathosterol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2." [EC:1.14.21.6, MetaCyc:LATHOSTEROL-OXIDASE-RXN] +synonym: "5-DES" RELATED [EC:1.14.21.6] +synonym: "5alpha-cholest-7-en-3beta-ol, NAD(P)H:oxygen 5-oxidoreductase activity" EXACT [EC:1.14.21.6] +synonym: "delta7-sterol 5-desaturase activity" EXACT [EC:1.14.21.6] +synonym: "delta7-sterol delta5-dehydrogenase activity" EXACT [EC:1.14.21.6] +synonym: "delta7-sterol-C5(6)-desaturase activity" EXACT [EC:1.14.21.6] +synonym: "lathosterol 5-desaturase activity" EXACT [EC:1.14.21.6] +xref: EC:1.14.21.6 +xref: MetaCyc:1.14.21.6-RXN +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated +is_a: GO:0070704 ! sterol desaturase activity + +[Term] +id: GO:0050047 +name: leucine 2,3-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine = (3R)-beta-leucine." [EC:5.4.3.7, RHEA:10284] +synonym: "(2S)-alpha-leucine 2,3-aminomutase activity" EXACT [EC:5.4.3.7] +xref: EC:5.4.3.7 +xref: KEGG_REACTION:R01091 +xref: MetaCyc:LEUCINE-23-AMINOMUTASE-RXN +xref: RHEA:10284 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0050048 +name: L-leucine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate." [EC:2.6.1.6, MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN] +synonym: "L-leucine aminotransferase activity" BROAD [EC:2.6.1.6] +synonym: "leucine 2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.6] +synonym: "leucine aminotransferase activity" BROAD [] +synonym: "leucine transaminase activity" BROAD [EC:2.6.1.6] +synonym: "leucine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.6] +xref: EC:2.6.1.6 +xref: MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN +xref: RHEA:18321 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050049 +name: leucine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH." [EC:1.4.1.9, MetaCyc:LEUCINE-DEHYDROGENASE-RXN] +synonym: "L-leucine dehydrogenase activity" EXACT [EC:1.4.1.9] +synonym: "L-leucine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.9] +synonym: "L-leucine:NAD+ oxidoreductase, deaminating" EXACT [EC:1.4.1.9] +synonym: "LeuDH activity" EXACT [EC:1.4.1.9] +xref: EC:1.4.1.9 +xref: MetaCyc:LEUCINE-DEHYDROGENASE-RXN +xref: RHEA:12220 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050050 +name: leucine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+)." [EC:2.3.1.66, RHEA:20089] +synonym: "acetyl-CoA:L-leucine N-acetyltransferase activity" EXACT [EC:2.3.1.66] +synonym: "leucine acetyltransferase activity" EXACT [EC:2.3.1.66] +xref: EC:2.3.1.66 +xref: KEGG_REACTION:R01089 +xref: MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:20089 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0050051 +name: leukotriene-B4 20-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O." [MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN, RHEA:22176] +synonym: "leukotriene-B4 20-hydroxylase activity" EXACT [EC:1.14.14.94] +synonym: "leukotriene-B4 omega-hydroxylase activity" EXACT [EC:1.14.14.94] +synonym: "LTB(4) 20-hydroxylase activity" EXACT [EC:1.14.14.94] +synonym: "LTB(4) omega-hydroxylase activity" EXACT [EC:1.14.14.94] +synonym: "LTB4 20-hydroxylase activity" EXACT [EC:1.14.14.94] +synonym: "LTB4 omega-hydroxylase activity" EXACT [EC:1.14.14.94] +xref: EC:1.14.14.94 +xref: MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-211873 "CYP4F2, 4F3 20-hydroxylate LTB4" +xref: RHEA:22176 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +relationship: part_of GO:0036101 ! leukotriene B4 catabolic process + +[Term] +id: GO:0050052 +name: leukotriene-E4 20-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+)." [EC:1.14.13.34, RHEA:24120] +synonym: "(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)" EXACT [EC:1.14.13.34] +synonym: "leukotriene-E(4) omega-hydroxylase activity" EXACT [EC:1.14.13.34] +synonym: "leukotriene-E4 omega-hydroxylase activity" EXACT [EC:1.14.13.34] +synonym: "leukotriene-E4 w-hydroxylase activity" EXACT [] +xref: EC:1.14.13.34 +xref: KEGG_REACTION:R04256 +xref: MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN +xref: RHEA:24120 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050053 +name: levansucrase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1)." [EC:2.4.1.10, MetaCyc:LEVANSUCRASE-RXN] +synonym: "beta-2,6-fructan:D-glucose 1-fructosyltransferase activity" EXACT [EC:2.4.1.10] +synonym: "beta-2,6-fructosyltransferase activity" EXACT [EC:2.4.1.10] +synonym: "sucrose 6-fructosyl transferase activity" EXACT [EC:2.4.1.10] +synonym: "sucrose 6-fructosyltransferase activity" EXACT [EC:2.4.1.10] +synonym: "sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.10] +xref: EC:2.4.1.10 +xref: MetaCyc:LEVANSUCRASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050054 +name: lignostilbene alpha beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin." [EC:1.13.11.43, RHEA:21340] +synonym: "1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)" EXACT [EC:1.13.11.43] +synonym: "lignostilbene ab-dioxygenase activity" EXACT [] +synonym: "lignostilbene alphabeta-dioxygenase activity" EXACT [EC:1.13.11.43] +xref: EC:1.13.11.43 +xref: KEGG_REACTION:R00043 +xref: MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN +xref: RHEA:21340 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050055 +name: limonin-D-ring-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate." [EC:3.1.1.36, MetaCyc:LIMONIN-D-RING-LACTONASE-RXN] +synonym: "limonin lactone hydrolase activity" EXACT [EC:3.1.1.36] +synonym: "limonin-D-ring-lactone hydrolase activity" EXACT [EC:3.1.1.36] +synonym: "limonoate-D-ring-lactone lactonohydrolase activity" EXACT [EC:3.1.1.36] +xref: EC:3.1.1.36 +xref: MetaCyc:LIMONIN-D-RING-LACTONASE-RXN +xref: RHEA:10896 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050056 +name: linalool 8-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O." [EC:1.14.99.28, RHEA:20760] +synonym: "3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.99.28] +xref: EC:1.14.99.28 +xref: KEGG_REACTION:R04366 +xref: MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN +xref: RHEA:20760 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050057 +name: linamarin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin." [EC:2.4.1.63, MetaCyc:LINAMARIN-SYNTHASE-RXN] +synonym: "UDP glucose ketone cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.63] +synonym: "uridine diphosphoglucose-ketone glucosyltransferase activity" EXACT [EC:2.4.1.63] +xref: EC:2.4.1.63 +xref: MetaCyc:LINAMARIN-SYNTHASE-RXN +xref: RHEA:20009 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050058 +name: linoleate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate." [EC:5.2.1.5, RHEA:17381] +synonym: "linoleate delta12-cis-delta11-trans-isomerase activity" EXACT [EC:5.2.1.5] +synonym: "linoleic acid isomerase activity" EXACT [EC:5.2.1.5] +xref: EC:5.2.1.5 +xref: KEGG_REACTION:R03627 +xref: MetaCyc:LINOLEATE-ISOMERASE-RXN +xref: RHEA:17381 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0050059 +name: lombricine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine." [EC:2.7.3.5, MetaCyc:LOMBRICINE-KINASE-RXN] +synonym: "ATP:lombricine N-phosphotransferase activity" EXACT [EC:2.7.3.5] +xref: EC:2.7.3.5 +xref: MetaCyc:LOMBRICINE-KINASE-RXN +xref: RHEA:23292 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0050060 +name: long-chain-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH." [EC:1.1.1.192, MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN] +synonym: "fatty alcohol oxidoreductase activity" EXACT [EC:1.1.1.192] +synonym: "long-chain alcohol dehydrogenase activity" EXACT [EC:1.1.1.192] +synonym: "long-chain-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.192] +xref: EC:1.1.1.192 +xref: MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050061 +name: long-chain-aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons." [EC:1.2.1.48, MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN] +synonym: "fatty aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.48] +synonym: "long-chain aliphatic aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] +synonym: "long-chain fatty aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] +synonym: "long-chain-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.48] +xref: EC:1.2.1.48 +xref: MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN +xref: UM-BBD_reactionID:r1404 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0050062 +name: long-chain-fatty-acyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH." [EC:1.2.1.50, MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN] +synonym: "acyl coenzyme A reductase activity" EXACT [EC:1.2.1.50] +synonym: "long-chain fatty acyl CoA reductase activity" EXACT [] +synonym: "long-chain fatty acyl-CoA reductase activity" EXACT [GOC:mah] +synonym: "long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)" EXACT [EC:1.2.1.50] +xref: EC:1.2.1.50 +xref: MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050063 +name: obsolete low-density-lipoprotein particle receptor kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine." [EC:2.7.11.29, MetaCyc:LOW-DENSITY-LIPOPROTEIN-KINASE-RXN] +comment: This term was made obsolete because it represents a specific gene product. +synonym: "[low-density lipoprotein receptor] kinase activity" EXACT [] +synonym: "ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity" EXACT [EC:2.7.11.29] +synonym: "ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity" EXACT [EC:2.7.11.29] +synonym: "LDL receptor kinase activity" EXACT [EC:2.7.11.29] +synonym: "low-density lipoprotein receptor kinase activity" EXACT [EC:2.7.11.29] +synonym: "low-density-lipoprotein kinase activity" BROAD [EC:2.7.11.29] +synonym: "low-density-lipoprotein receptor kinase (phosphorylating) activity" EXACT [EC:2.7.11.29] +synonym: "low-density-lipoprotein receptor kinase activity" EXACT [GOC:dph] +synonym: "STK7" RELATED [EC:2.7.11.29] +xref: EC:2.7.11.29 +xref: MetaCyc:2.7.11.29-RXN +is_obsolete: true + +[Term] +id: GO:0050064 +name: luteolin 7-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP." [EC:2.4.1.189, RHEA:10568] +synonym: "LGT" RELATED [EC:2.4.1.189] +synonym: "luteolin 7-O-glucoronosyltransferase activity" EXACT [] +synonym: "UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] +synonym: "UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] +synonym: "uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] +xref: EC:2.4.1.189 +xref: KEGG_REACTION:R03589 +xref: MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN +xref: RHEA:10568 +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0050065 +name: lysine-pyruvate 6-transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine." [EC:2.6.1.71, RHEA:19393] +synonym: "L-lysine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.71] +synonym: "Lys-AT" RELATED [EC:2.6.1.71] +synonym: "lysine--pyruvate 6-aminotransferase activity" EXACT [] +synonym: "lysine-pyruvate aminotransferase activity" EXACT [EC:2.6.1.71] +xref: EC:2.6.1.71 +xref: KEGG_REACTION:R00453 +xref: MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN +xref: MetaCyc:PWY-5324 +xref: RHEA:19393 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050066 +name: lysine 2,3-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate." [EC:5.4.3.2, RHEA:19177] +synonym: "L-lysine 2,3-aminomutase activity" EXACT [EC:5.4.3.2] +xref: EC:5.4.3.2 +xref: KEGG_REACTION:R00461 +xref: MetaCyc:LYSINE-23-AMINOMUTASE-RXN +xref: RHEA:19177 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0050067 +name: lysine 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O." [EC:1.13.12.2, RHEA:14601] +synonym: "L-lysine-2-monooxygenase activity" EXACT [EC:1.13.12.2] +synonym: "L-lysine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.2] +synonym: "lysine monooxygenase activity" EXACT [EC:1.13.12.2] +synonym: "lysine oxygenase activity" EXACT [EC:1.13.12.2] +xref: EC:1.13.12.2 +xref: KEGG_REACTION:R00449 +xref: MetaCyc:LYSINE-2-MONOOXYGENASE-RXN +xref: RHEA:14601 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0050068 +name: lysine carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate." [EC:2.1.3.8, RHEA:17121] +synonym: "carbamoyl-phosphate:L-lysine carbamoyltransferase activity" EXACT [EC:2.1.3.8] +synonym: "lysine transcarbamylase activity" EXACT [EC:2.1.3.8] +xref: EC:2.1.3.8 +xref: KEGG_REACTION:R01396 +xref: MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN +xref: RHEA:17121 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0050069 +name: lysine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH." [EC:1.4.1.15, MetaCyc:LYSINE-DEHYDROGENASE-RXN] +synonym: "L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)" EXACT [EC:1.4.1.15] +xref: EC:1.4.1.15 +xref: MetaCyc:LYSINE-DEHYDROGENASE-RXN +xref: RHEA:18505 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050070 +name: lysolecithin acylmutase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine." [EC:5.4.1.1, RHEA:24356] +synonym: "lysolecithin 2,3-acylmutase activity" EXACT [EC:5.4.1.1] +synonym: "lysolecithin migratase activity" RELATED [EC:5.4.1.1] +xref: EC:5.4.1.1 +xref: KEGG_REACTION:R03334 +xref: MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN +xref: RHEA:24356 +is_a: GO:0016867 ! intramolecular transferase activity, transferring acyl groups + +[Term] +id: GO:0050071 +name: lysyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol." [EC:2.3.2.3, MetaCyc:LYSYLTRANSFERASE-RXN] +synonym: "L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity" EXACT [EC:2.3.2.3] +synonym: "L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity" EXACT [EC:2.3.2.3] +xref: EC:2.3.2.3 +xref: MetaCyc:LYSYLTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0050072 +name: m7G(5')pppN diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide." [EC:3.6.1.30, MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN] +synonym: "7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [EC:3.6.1.30] +synonym: "decapase activity" RELATED [EC:3.6.1.30] +synonym: "M(7)G(5')pppN pyrophosphatase activity" EXACT [] +synonym: "m7G(5')pppN pyrophosphatase activity" EXACT [EC:3.6.1.30] +xref: EC:3.6.1.30 +xref: MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0050073 +name: macrolide 2'-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate." [EC:2.7.1.136, RHEA:18333] +synonym: "ATP:macrolide 2'-O-phosphotransferase activity" EXACT [EC:2.7.1.136] +xref: EC:2.7.1.136 +xref: KEGG_REACTION:R03780 +xref: MetaCyc:MACROLIDE-2-KINASE-RXN +xref: RHEA:18333 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050074 +name: malate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA." [EC:6.2.1.9, MetaCyc:MALATE--COA-LIGASE-RXN] +synonym: "malate thiokinase activity" RELATED [EC:6.2.1.9] +synonym: "malate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.9] +synonym: "malyl coenzyme A synthetase activity" EXACT [EC:6.2.1.9] +synonym: "malyl-CoA synthetase activity" EXACT [EC:6.2.1.9] +xref: EC:6.2.1.9 +xref: MetaCyc:MALATE--COA-LIGASE-RXN +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0050075 +name: maleate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-malate = H(2)O + maleate." [EC:4.2.1.31, RHEA:23692] +synonym: "(R)-malate hydro-lyase (maleate-forming)" EXACT [EC:4.2.1.31] +synonym: "(R)-malate hydro-lyase activity" EXACT [EC:4.2.1.31] +synonym: "D-malate hydro-lyase activity" EXACT [EC:4.2.1.31] +synonym: "malease activity" EXACT [EC:4.2.1.31] +xref: EC:4.2.1.31 +xref: KEGG_REACTION:R02419 +xref: MetaCyc:MALEATE-HYDRATASE-RXN +xref: RHEA:23692 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050076 +name: maleate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: maleate = fumarate." [EC:5.2.1.1, RHEA:13169] +synonym: "maleate cis-trans-isomerase activity" EXACT [EC:5.2.1.1] +xref: EC:5.2.1.1 +xref: KEGG_REACTION:R01087 +xref: MetaCyc:MALEATE-ISOMERASE-RXN +xref: RHEA:13169 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0050077 +name: maleylpyruvate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate." [EC:5.2.1.4, MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN] +synonym: "3-maleylpyruvate cis-trans-isomerase activity" EXACT [EC:5.2.1.4] +xref: EC:5.2.1.4 +xref: MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN +xref: RHEA:17393 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0050078 +name: malonate CoA-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA." [EC:2.8.3.3, RHEA:18817] +synonym: "acetyl-CoA:malonate CoA-transferase activity" EXACT [EC:2.8.3.3] +synonym: "malonate coenzyme A-transferase activity" EXACT [EC:2.8.3.3] +xref: EC:2.8.3.3 +xref: KEGG_REACTION:R00743 +xref: MetaCyc:MALONATE-COA-TRANSFERASE-RXN +xref: RHEA:18817 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0050079 +name: acetylenecarboxylate hydratase activity, producing 3-oxopropanoate +namespace: molecular_function +alt_id: GO:0047607 +def: "Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O." [EC:4.2.1.27, MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN] +comment: Note that this function was formerly EC:4.2.1.71. +synonym: "3-oxopropanoate hydro-lyase (propynoate-forming)" EXACT [EC:4.2.1.27] +synonym: "3-oxopropanoate hydro-lyase activity" EXACT [EC:4.2.1.27] +synonym: "acetylenecarboxylate hydratase activity" BROAD [] +synonym: "acetylenecarboxylate hydratase activity, producing malonate-semialdehyde" EXACT [] +synonym: "acetylenemonocarboxylate hydrase activity" EXACT [EC:4.2.1.27] +synonym: "acetylenemonocarboxylate hydratase activity" BROAD [] +synonym: "acetylmonocarboxylic acid hydrase activity" EXACT [EC:4.2.1.27] +synonym: "alkynoate hydratase activity" BROAD [] +synonym: "malonate-semialdehyde dehydratase activity" EXACT [] +xref: EC:4.2.1.27 +xref: MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN +xref: RHEA:17957 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050080 +name: malonyl-CoA decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2." [EC:4.1.1.9, MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN] +synonym: "malonyl coenzyme A decarboxylase activity" EXACT [EC:4.1.1.9] +synonym: "malonyl-CoA carboxy-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.1.9] +synonym: "malonyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.9] +xref: EC:4.1.1.9 +xref: MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN +xref: Reactome:R-HSA-977317 "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome" +xref: RHEA:18781 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050081 +name: maltose-6'-phosphate glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate." [EC:3.2.1.122, MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN] +synonym: "maltose-6'-phosphate 6-phosphoglucohydrolase activity" EXACT [EC:3.2.1.122] +synonym: "phospho-alpha-glucosidase activity" EXACT [EC:3.2.1.122] +xref: EC:3.2.1.122 +xref: MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN +xref: RHEA:20421 +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0050082 +name: maltose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate." [EC:2.4.1.8, MetaCyc:MALTOSE-PHOSPHORYLASE-RXN] +synonym: "maltose:phosphate 1-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.8] +xref: EC:2.4.1.8 +xref: MetaCyc:MALTOSE-PHOSPHORYLASE-RXN +xref: RHEA:21116 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0050083 +name: malyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate." [EC:4.1.3.24, MetaCyc:MALYL-COA-LYASE-RXN] +synonym: "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.24] +synonym: "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity" EXACT [EC:4.1.3.24] +synonym: "malyl-coenzyme A lyase activity" EXACT [EC:4.1.3.24] +xref: EC:4.1.3.24 +xref: MetaCyc:MALYL-COA-LYASE-RXN +xref: RHEA:16629 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0050084 +name: mannitol-1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate." [EC:3.1.3.22, RHEA:19537] +synonym: "D-mannitol-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.22] +synonym: "mannitol-1-phosphate phosphatase activity" EXACT [EC:3.1.3.22] +xref: EC:3.1.3.22 +xref: KEGG_REACTION:R02167 +xref: MetaCyc:MANNITOL-1-PHOSPHATASE-RXN +xref: RHEA:19537 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050085 +name: mannitol 2-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH." [EC:1.1.1.138, RHEA:16765] +synonym: "D-mannitol:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.138] +synonym: "NADP-dependent mannitol dehydrogenase activity" EXACT [EC:1.1.1.138] +xref: EC:1.1.1.138 +xref: KEGG_REACTION:R00870 +xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN +xref: RHEA:16765 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050086 +name: mannitol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH." [EC:1.1.1.67, MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN] +synonym: "D-mannitol dehydrogenase activity" EXACT [EC:1.1.1.67] +synonym: "D-mannitol:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.67] +xref: EC:1.1.1.67 +xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN +xref: RHEA:12084 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050087 +name: mannitol dehydrogenase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c." [EC:1.1.2.2, MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN] +synonym: "D-mannitol:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.2] +synonym: "polyol dehydrogenase activity" BROAD [EC:1.1.2.2] +xref: EC:1.1.2.2 +xref: MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0050088 +name: mannose-6-phosphate 6-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH." [EC:1.1.1.224, RHEA:14925] +synonym: "6-phosphomannose reductase activity" EXACT [EC:1.1.1.224] +synonym: "D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.224] +synonym: "mannose-6-phosphate reductase activity" EXACT [EC:1.1.1.224] +synonym: "NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity" EXACT [EC:1.1.1.224] +synonym: "NADPH-dependent M6P reductase activity" EXACT [EC:1.1.1.224] +synonym: "NADPH-dependent mannose 6-phosphate reductase activity" EXACT [EC:1.1.1.224] +synonym: "NADPH-mannose-6-P reductase activity" EXACT [EC:1.1.1.224] +xref: EC:1.1.1.224 +xref: KEGG_REACTION:R01817 +xref: MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN +xref: RHEA:14925 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050089 +name: mannose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannose = D-fructose." [EC:5.3.1.7, RHEA:22604] +synonym: "D-mannose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.7] +synonym: "D-mannose isomerase activity" EXACT [EC:5.3.1.7] +synonym: "D-mannose ketol-isomerase activity" EXACT [EC:5.3.1.7] +xref: EC:5.3.1.7 +xref: KEGG_REACTION:R00877 +xref: MetaCyc:MANNOSE-ISOMERASE-RXN +xref: RHEA:22604 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0050090 +name: mannuronate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+." [EC:1.1.1.131, MetaCyc:MANNURONATE-REDUCTASE-RXN] +synonym: "D-mannonate:NAD(P)+ 6-oxidoreductase activity" EXACT [EC:1.1.1.131] +synonym: "D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))" EXACT [EC:1.1.1.131] +synonym: "mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity" EXACT [EC:1.1.1.131] +synonym: "mannonate dehydrogenase (NAD(P)+)" EXACT [EC:1.1.1.131] +synonym: "mannonate dehydrogenase activity" EXACT [EC:1.1.1.131] +xref: EC:1.1.1.131 +xref: MetaCyc:MANNURONATE-REDUCTASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050091 +name: melilotate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+)." [EC:1.14.13.4, RHEA:17669] +synonym: "2-hydroxyphenylpropionate hydroxylase activity" EXACT [EC:1.14.13.4] +synonym: "2-hydroxyphenylpropionic hydroxylase activity" EXACT [EC:1.14.13.4] +synonym: "3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.4] +synonym: "melilotate hydroxylase activity" EXACT [] +synonym: "melilotic hydroxylase activity" EXACT [EC:1.14.13.4] +xref: EC:1.14.13.4 +xref: KEGG_REACTION:R03369 +xref: MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN +xref: RHEA:17669 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050092 +name: meso-tartrate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH." [EC:1.3.1.7, RHEA:18553] +synonym: "meso-tartrate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.7] +xref: EC:1.3.1.7 +xref: KEGG_REACTION:R02544 +xref: MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN +xref: RHEA:18553 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050093 +name: methanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH." [EC:1.1.1.244, RHEA:19401] +synonym: "methanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.244] +xref: EC:1.1.1.244 +xref: KEGG_REACTION:R00605 +xref: MetaCyc:METHANOL-DEHYDROGENASE-RXN +xref: RHEA:19401 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050094 +name: methionine-glyoxylate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine." [EC:2.6.1.73, RHEA:22884] +synonym: "L-methionine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.73] +synonym: "methionine-glyoxylate aminotransferase activity" EXACT [EC:2.6.1.73] +synonym: "MGAT activity" EXACT [EC:2.6.1.73] +xref: EC:2.6.1.73 +xref: KEGG_REACTION:R00652 +xref: MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN +xref: RHEA:22884 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050095 +name: methionine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2)." [EC:4.1.1.57, RHEA:17757] +synonym: "L-methionine carboxy-lyase (3-methylthiopropanamine-forming)" EXACT [EC:4.1.1.57] +synonym: "L-methionine carboxy-lyase activity" EXACT [EC:4.1.1.57] +synonym: "L-methionine decarboxylase activity" EXACT [EC:4.1.1.57] +xref: EC:4.1.1.57 +xref: KEGG_REACTION:R00656 +xref: MetaCyc:METHIONINE-DECARBOXYLASE-RXN +xref: RHEA:17757 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050096 +name: methylaspartate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+)." [EC:4.3.1.2, RHEA:12829] +synonym: "3-methylaspartase activity" EXACT [EC:4.3.1.2] +synonym: "beta-methylaspartase activity" EXACT [EC:4.3.1.2] +synonym: "L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)" EXACT [EC:4.3.1.2] +synonym: "L-threo-3-methylaspartate ammonia-lyase activity" EXACT [EC:4.3.1.2] +xref: EC:4.3.1.2 +xref: KEGG_REACTION:R03696 +xref: MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN +xref: RHEA:12829 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0050097 +name: methylaspartate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate." [EC:5.4.99.1, RHEA:12857] +synonym: "b-methylaspartate-glutamate mutase activity" EXACT [EC:5.4.99.1] +synonym: "beta-methylaspartate-glutamate mutase activity" EXACT [EC:5.4.99.1] +synonym: "glutamate isomerase activity" EXACT [EC:5.4.99.1] +synonym: "glutamate mutase activity" EXACT [EC:5.4.99.1] +synonym: "glutamic acid isomerase activity" EXACT [EC:5.4.99.1] +synonym: "glutamic acid mutase activity" EXACT [EC:5.4.99.1] +synonym: "glutamic isomerase activity" EXACT [EC:5.4.99.1] +synonym: "glutamic mutase activity" EXACT [EC:5.4.99.1] +synonym: "L-threo-3-methylaspartate carboxy-aminomethylmutase activity" EXACT [EC:5.4.99.1] +synonym: "methylaspartic acid mutase activity" EXACT [EC:5.4.99.1] +xref: EC:5.4.99.1 +xref: KEGG_REACTION:R00262 +xref: MetaCyc:METHYLASPARTATE-MUTASE-RXN +xref: RHEA:12857 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0050098 +name: methylguanidinase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea." [EC:3.5.3.16, RHEA:11764] +synonym: "methylguanidine amidinohydrolase activity" EXACT [EC:3.5.3.16] +synonym: "methylguanidine hydrolase activity" EXACT [EC:3.5.3.16] +xref: EC:3.5.3.16 +xref: KEGG_REACTION:R01589 +xref: MetaCyc:METHYLGUANIDINASE-RXN +xref: RHEA:11764 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0050099 +name: methylglutamate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde." [EC:1.5.99.5, RHEA:22572] +synonym: "N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.99.5] +synonym: "N-methyl-L-glutamate:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.99.5] +synonym: "N-methylglutamate dehydrogenase activity" EXACT [EC:1.5.99.5] +xref: EC:1.5.99.5 +xref: KEGG_REACTION:R00609 +xref: MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN +xref: RHEA:22572 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0050100 +name: methylitaconate delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate." [EC:5.3.3.6, RHEA:23480] +synonym: "methylitaconate D-isomerase activity" EXACT [] +synonym: "methylitaconate delta2-delta3-isomerase activity" EXACT [EC:5.3.3.6] +synonym: "methylitaconate isomerase activity" EXACT [EC:5.3.3.6] +xref: EC:5.3.3.6 +xref: KEGG_REACTION:R03070 +xref: MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN +xref: RHEA:23480 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0050101 +name: mimosinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine." [EC:3.5.1.61, RHEA:13373] +synonym: "mimosine amidohydrolase activity" EXACT [EC:3.5.1.61] +xref: EC:3.5.1.61 +xref: KEGG_REACTION:R04350 +xref: MetaCyc:MIMOSINASE-RXN +xref: RHEA:13373 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050102 +name: cellodextrin phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate." [EC:2.4.1.49, MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN] +synonym: "1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.49] +synonym: "beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity" EXACT [EC:2.4.1.49] +xref: EC:2.4.1.49 +xref: MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050103 +name: dextrin dextranase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1)." [EC:2.4.1.2, MetaCyc:DEXTRIN-DEXTRANASE-RXN] +synonym: "1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.2] +synonym: "dextran dextrinase activity" EXACT [EC:2.4.1.2] +synonym: "dextrin 6-glucosyltransferase activity" EXACT [EC:2.4.1.2] +xref: EC:2.4.1.2 +xref: MetaCyc:DEXTRIN-DEXTRANASE-RXN +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050104 +name: L-gulonate 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH." [EC:1.1.1.45, RHEA:12889] +synonym: "L-3-aldonate dehydrogenase activity" EXACT [EC:1.1.1.45] +synonym: "L-3-aldonic dehydrogenase activity" EXACT [EC:1.1.1.45] +synonym: "L-3-hydroxyacid dehydrogenase activity" EXACT [EC:1.1.1.45] +synonym: "L-beta-hydroxy-acid-NAD-oxidoreductase activity" EXACT [EC:1.1.1.45] +synonym: "L-beta-hydroxyacid dehydrogenase activity" EXACT [EC:1.1.1.45] +synonym: "L-gulonate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.45] +synonym: "L-gulonic acid dehydrogenase activity" EXACT [EC:1.1.1.45] +xref: EC:1.1.1.45 +xref: KEGG_REACTION:R02640 +xref: MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN +xref: Reactome:R-HSA-5661290 "CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate" +xref: RHEA:12889 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050105 +name: L-gulonolactone oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2." [EC:1.1.3.8, MetaCyc:L-GULONOLACTONE-OXIDASE-RXN, RHEA:32363] +synonym: "GLO activity" EXACT [EC:1.1.3.8] +synonym: "L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity" EXACT [EC:1.1.3.8] +synonym: "L-gulono-gamma-lactone oxidase activity" EXACT [EC:1.1.3.8] +synonym: "L-gulono-gamma-lactone:O2 oxidoreductase activity" EXACT [EC:1.1.3.8] +synonym: "L-gulono-gamma-lactone:oxidoreductase activity" EXACT [EC:1.1.3.8] +xref: EC:1.1.3.8 +xref: MetaCyc:L-GULONOLACTONE-OXIDASE-RXN +xref: RHEA:32363 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050106 +name: monomethyl-sulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate." [EC:3.1.6.16, RHEA:14221] +synonym: "monomethyl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.16] +synonym: "monomethyl-sulphatase activity" EXACT [] +xref: EC:3.1.6.16 +xref: KEGG_REACTION:R01145 +xref: MetaCyc:MONOMETHYL-SULFATASE-RXN +xref: RHEA:14221 +is_a: GO:0008484 ! sulfuric ester hydrolase activity + +[Term] +id: GO:0050107 +name: monoterpenol O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester." [EC:2.3.1.69, MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN] +synonym: "acetyl-CoA:monoterpenol O-acetyltransferase activity" EXACT [EC:2.3.1.69] +synonym: "menthol transacetylase activity" NARROW [EC:2.3.1.69] +xref: EC:2.3.1.69 +xref: MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050108 +name: monoterpenyl-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate." [EC:3.1.7.3, MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN] +synonym: "bornyl diphosphate hydrolase activity" EXACT [EC:3.1.7.3] +synonym: "bornyl pyrophosphate hydrolase activity" EXACT [EC:3.1.7.3] +synonym: "monoterpenyl-diphosphate diphosphohydrolase activity" EXACT [EC:3.1.7.3] +synonym: "monoterpenyl-pyrophosphatase activity" EXACT [] +xref: EC:3.1.7.3 +xref: MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN +is_a: GO:0016794 ! diphosphoric monoester hydrolase activity + +[Term] +id: GO:0050109 +name: morphine 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+." [EC:1.1.1.218, MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN] +synonym: "morphine:NAD(P)+ 6-oxidoreductase activity" EXACT [EC:1.1.1.218] +synonym: "naloxone reductase activity" EXACT [EC:1.1.1.218] +synonym: "reductase, naloxone" EXACT [EC:1.1.1.218] +xref: EC:1.1.1.218 +xref: MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050110 +name: mucinaminylserine mucinaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine." [MetaCyc:3.2.1.110-RXN] +synonym: "D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity" EXACT [EC:3.2.1.110] +synonym: "endo-beta-N-acetyl-D-galactosaminidase activity" BROAD [EC:3.2.1.110] +synonym: "endo-beta-N-acetylgalactosaminidase" BROAD [EC:3.2.1.110] +xref: EC:3.2.1.97 +xref: KEGG_REACTION:R04527 +xref: MetaCyc:3.2.1.110-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0050111 +name: mycocerosate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+)." [EC:2.3.1.111, RHEA:10588] +synonym: "acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)" EXACT [EC:2.3.1.111] +synonym: "mycocerosic acid synthase activity" EXACT [EC:2.3.1.111] +xref: EC:2.3.1.111 +xref: KEGG_REACTION:R05189 +xref: MetaCyc:MYCOCEROSATE-SYNTHASE-RXN +xref: RHEA:10588 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050112 +name: inositol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH." [EC:1.1.1.18, RHEA:16949] +synonym: "inositol:NAD 2-dehydrogenase activity" EXACT [] +synonym: "myo-inositol 2-dehydrogenase activity" EXACT [] +xref: EC:1.1.1.18 +xref: KEGG_REACTION:R01183 +xref: MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN +xref: RHEA:16949 +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity + +[Term] +id: GO:0050113 +name: inositol oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+)." [EC:1.13.99.1, RHEA:23696] +synonym: "meso-inositol oxygenase activity" EXACT [EC:1.13.99.1] +synonym: "MOO activity" EXACT [EC:1.13.99.1] +synonym: "myo-inositol oxygenase activity" EXACT [] +synonym: "myo-inositol:oxygen oxidoreductase activity" EXACT [EC:1.13.99.1] +xref: EC:1.13.99.1 +xref: KEGG_REACTION:R01184 +xref: MetaCyc:MYO-INOSITOL-OXYGENASE-RXN +xref: Reactome:R-HSA-5678327 "MIOX oxidises Ins to GlcA" +xref: RHEA:23696 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0050114 +name: myo-inosose-2 dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O." [EC:4.2.1.44, RHEA:14065] +synonym: "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)" EXACT [EC:4.2.1.44] +synonym: "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity" EXACT [EC:4.2.1.44] +synonym: "inosose 2,3-dehydratase activity" EXACT [EC:4.2.1.44] +synonym: "ketoinositol dehydratase activity" EXACT [EC:4.2.1.44] +xref: EC:4.2.1.44 +xref: KEGG_REACTION:R02782 +xref: MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN +xref: RHEA:14065 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050115 +name: myosin-light-chain-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate." [EC:3.1.3.53, MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN] +synonym: "[Myosin light-chain]-phosphatase activity" EXACT [] +synonym: "myosin light chain kinase phosphatase activity" EXACT [EC:3.1.3.53] +synonym: "myosin light-chain kinase phosphatase activity" RELATED [EC:3.1.3.53] +synonym: "myosin-light-chain phosphatase activity" EXACT [EC:3.1.3.53] +synonym: "myosin-light-chain-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.53] +synonym: "protein phosphatase 2A" RELATED [EC:3.1.3.53] +xref: EC:3.1.3.53 +xref: MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN +xref: Reactome:R-HSA-419232 "Myosin phosphatase dephosphorylates myosin regulatory light chain" +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0050116 +name: N,N-dimethylformamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate." [EC:3.5.1.56, RHEA:19517] +synonym: "dimethylformamidase activity" EXACT [EC:3.5.1.56] +synonym: "DMFase activity" EXACT [EC:3.5.1.56] +synonym: "N,N-dimethylformamide amidohydrolase activity" EXACT [EC:3.5.1.56] +xref: EC:3.5.1.56 +xref: KEGG_REACTION:R02509 +xref: MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN +xref: RHEA:19517 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050117 +name: N-acetyl-beta-alanine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate." [EC:3.5.1.21, RHEA:23212] +synonym: "N-acetyl-beta-alanine amidohydrolase activity" EXACT [EC:3.5.1.21] +xref: EC:3.5.1.21 +xref: KEGG_REACTION:R00909 +xref: MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN +xref: RHEA:23212 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0050118 +name: N-acetyldiaminopimelate deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate." [EC:3.5.1.47, RHEA:20405] +synonym: "6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.47] +synonym: "N-acetyl-L-diaminopimelic acid deacylase activity" EXACT [EC:3.5.1.47] +synonym: "N-acetyl-LL-diaminopimelate deacylase activity" EXACT [EC:3.5.1.47] +synonym: "N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.47] +xref: EC:3.5.1.47 +xref: KEGG_REACTION:R02733 +xref: MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN +xref: RHEA:20405 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0050119 +name: N-acetylglucosamine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate." [EC:3.5.1.33, RHEA:20593] +synonym: "acetylaminodeoxyglucose acetylhydrolase activity" EXACT [EC:3.5.1.33] +synonym: "N-acetyl-D-glucosamine amidohydrolase activity" EXACT [EC:3.5.1.33] +synonym: "N-acetyl-D-glucosaminyl N-deacetylase activity" EXACT [EC:3.5.1.33] +xref: EC:3.5.1.33 +xref: KEGG_REACTION:R01200 +xref: MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN +xref: Reactome:R-HSA-2022887 "NDST1-4 N-deacetylates GlcNAc residues in heparan" +xref: RHEA:20593 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +is_a: GO:0019213 ! deacetylase activity + +[Term] +id: GO:0050120 +name: N-acetylhexosamine 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH." [EC:1.1.1.240, RHEA:23144] +synonym: "N-acetyl-D-hexosamine dehydrogenase activity" EXACT [EC:1.1.1.240] +synonym: "N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.240] +synonym: "N-acetylhexosamine dehydrogenase activity" EXACT [EC:1.1.1.240] +xref: EC:1.1.1.240 +xref: KEGG_REACTION:R01202 +xref: MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN +xref: RHEA:23144 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050121 +name: N-acylglucosamine 2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine." [EC:5.1.3.8, MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN] +synonym: "acylglucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] +synonym: "GlcNAc 2-epimerase activity" EXACT [EC:5.1.3.8] +synonym: "N-acetyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] +synonym: "N-acetylglucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] +synonym: "N-acyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] +xref: EC:5.1.3.8 +xref: MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN +xref: Reactome:R-HSA-6803761 "RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc" +xref: RHEA:19033 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050122 +name: N-acylhexosamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+)." [EC:1.1.3.29, RHEA:13029] +synonym: "N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.29] +synonym: "N-acyl-D-hexosamine oxidase activity" EXACT [EC:1.1.3.29] +synonym: "N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.29] +xref: EC:1.1.3.29 +xref: KEGG_REACTION:R01203 +xref: MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN +xref: RHEA:13029 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050123 +name: N-acylmannosamine 1-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH." [EC:1.1.1.233, RHEA:11540] +synonym: "N-acetyl-D-mannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] +synonym: "N-acyl-D-mannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] +synonym: "N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.233] +synonym: "N-acylmannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] +xref: EC:1.1.1.233 +xref: KEGG_REACTION:R02651 +xref: MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN +xref: RHEA:11540 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050124 +name: N-acylneuraminate-9-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate." [EC:3.1.3.29, MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN] +synonym: "acylneuraminate 9-phosphatase activity" EXACT [EC:3.1.3.29] +synonym: "N-acylneuraminate-9-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.29] +synonym: "N-acylneuraminic (sialic) acid 9-phosphatase activity" EXACT [EC:3.1.3.29] +synonym: "N-acylneuraminic acid 9-phosphate phosphatase activity" EXACT [EC:3.1.3.29] +xref: EC:3.1.3.29 +xref: MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN +xref: Reactome:R-HSA-4084989 "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac" +xref: RHEA:13057 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050125 +name: N-benzyloxycarbonylglycine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine." [EC:3.5.1.58, RHEA:20900] +synonym: "benzyloxycarbonylglycine hydrolase activity" EXACT [EC:3.5.1.58] +synonym: "N-benzyloxycarbonylglycine urethanehydrolase activity" EXACT [EC:3.5.1.58] +synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity" EXACT [EC:3.5.1.58] +synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase I" RELATED [EC:3.5.1.58] +synonym: "nalpha-carbobenzoxyamino acid amidohydrolase activity" EXACT [EC:3.5.1.58] +xref: EC:3.5.1.58 +xref: KEGG_REACTION:R02551 +xref: MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN +xref: RHEA:20900 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050126 +name: N-carbamoylputrescine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine." [EC:3.5.1.53, RHEA:22284] +synonym: "carbamoylputrescine hydrolase activity" EXACT [EC:3.5.1.53] +synonym: "N-carbamoylputrescine amidohydrolase activity" EXACT [EC:3.5.1.53] +synonym: "NCP" RELATED [EC:3.5.1.53] +xref: EC:3.5.1.53 +xref: KEGG_REACTION:R01152 +xref: MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN +xref: RHEA:22284 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050127 +name: N-carbamoylsarcosine amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine." [EC:3.5.1.59, RHEA:20057] +synonym: "carbamoylsarcosine amidase activity" EXACT [EC:3.5.1.59] +synonym: "CSHase activity" EXACT [EC:3.5.1.59] +synonym: "N-carbamoylsarcosine amidohydrolase activity" EXACT [EC:3.5.1.59] +xref: EC:3.5.1.59 +xref: KEGG_REACTION:R01563 +xref: MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN +xref: RHEA:20057 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050128 +name: N-feruloylglycine deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine." [EC:3.5.1.71, RHEA:10484] +synonym: "N-feruloylglycine amidohydrolase activity" EXACT [EC:3.5.1.71] +synonym: "N-feruloylglycine hydrolase activity" EXACT [EC:3.5.1.71] +xref: EC:3.5.1.71 +xref: KEGG_REACTION:R03579 +xref: MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN +xref: RHEA:10484 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050129 +name: N-formylglutamate deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate." [EC:3.5.1.68, RHEA:12476] +synonym: "beta-citryl-L-glutamate amidase activity" EXACT [EC:3.5.1.68] +synonym: "beta-citryl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.68] +synonym: "beta-citryl-L-glutamate hydrolase activity" EXACT [EC:3.5.1.68] +synonym: "beta-citryl-L-glutamate-hydrolyzing enzyme" RELATED [EC:3.5.1.68] +synonym: "beta-citrylglutamate amidase activity" EXACT [EC:3.5.1.68] +synonym: "formylglutamate deformylase activity" EXACT [EC:3.5.1.68] +synonym: "N-formyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.68] +synonym: "N-formylglutamate hydrolase activity" EXACT [EC:3.5.1.68] +xref: EC:3.5.1.68 +xref: KEGG_REACTION:R00525 +xref: MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN +xref: RHEA:12476 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050130 +name: N-methyl-2-oxoglutaramate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium." [EC:3.5.1.36, RHEA:24108] +synonym: "5-hydroxy-N-methylpyroglutamate synthase activity" EXACT [EC:3.5.1.36] +synonym: "N-methyl-2-oxoglutaramate methylamidohydrolase activity" EXACT [EC:3.5.1.36] +xref: EC:3.5.1.36 +xref: KEGG_REACTION:R01587 +xref: MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN +xref: RHEA:24108 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050131 +name: N-methyl-L-amino-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2." [EC:1.5.3.2, MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN] +synonym: "N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.2] +synonym: "N-methylamino acid oxidase activity" EXACT [EC:1.5.3.2] +xref: EC:1.5.3.2 +xref: MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0050132 +name: N-methylalanine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate." [EC:1.4.1.17, RHEA:21768] +synonym: "N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)" EXACT [EC:1.4.1.17] +xref: EC:1.4.1.17 +xref: KEGG_REACTION:R01584 +xref: MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN +xref: RHEA:21768 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050133 +name: N6-hydroxylysine O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA." [EC:2.3.1.102, RHEA:22388] +synonym: "acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity" EXACT [EC:2.3.1.102] +synonym: "acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity" EXACT [EC:2.3.1.102] +synonym: "N(6)-hydroxylysine acetylase activity" EXACT [EC:2.3.1.102] +synonym: "N6-hydroxylysine acetylase activity" EXACT [EC:2.3.1.102] +synonym: "N6-hydroxylysine:acetyl CoA N6-transacetylase activity" EXACT [EC:2.3.1.102] +xref: EC:2.3.1.102 +xref: KEGG_REACTION:R03168 +xref: MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN +xref: RHEA:22388 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050134 +name: N6-methyl-lysine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2)." [EC:1.5.3.4, RHEA:23200] +synonym: "6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.4] +synonym: "epsilon-alkyl-L-lysine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.4] +synonym: "epsilon-alkyllysinase activity" EXACT [EC:1.5.3.4] +synonym: "epsilon-N-methyllysine demethylase activity" EXACT [EC:1.5.3.4] +synonym: "N(6)-methyllysine oxidase activity" EXACT [EC:1.5.3.4] +synonym: "N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.4] +synonym: "N6-methyllysine oxidase activity" EXACT [EC:1.5.3.4] +xref: EC:1.5.3.4 +xref: KEGG_REACTION:R00612 +xref: MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN +xref: RHEA:23200 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0050135 +name: NAD(P)+ nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide." [EC:3.2.2.6, MetaCyc:NADP+-NUCLEOSIDASE-RXN] +synonym: "NAD(P) nucleosidase activity" EXACT [] +synonym: "NAD(P)(+) nucleosidase activity" EXACT [] +synonym: "NAD(P)+ glycohydrolase activity" EXACT [EC:3.2.2.6] +synonym: "NAD(P)ase activity" EXACT [EC:3.2.2.6] +synonym: "nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity" EXACT [EC:3.2.2.6] +synonym: "nicotinamide adenine dinucleotide (phosphate) nucleosidase activity" EXACT [EC:3.2.2.6] +synonym: "triphosphopyridine nucleotidase activity" EXACT [EC:3.2.2.6] +xref: EC:3.2.2.6 +xref: MetaCyc:NADP+-NUCLEOSIDASE-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0050136 +name: NADH dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol." [EC:1.6.5.11, GOC:mah, MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN] +synonym: "D-diaphorase activity" EXACT [EC:1.6.5.11] +synonym: "DPNH-menadione reductase activity" EXACT [EC:1.6.5.11] +synonym: "NADH-quinone oxidoreductase activity" EXACT [EC:1.6.5.11] +synonym: "NADH:(quinone-acceptor) oxidoreductase activity" EXACT [EC:1.6.5.11] +synonym: "reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity" EXACT [EC:1.6.99.5] +xref: EC:1.6.5.11 +xref: MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN +xref: RHEA:46160 +is_a: GO:0003954 ! NADH dehydrogenase activity +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0050137 +name: NADPH peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+)." [EC:1.11.1.2, RHEA:15173] +synonym: "NADP peroxidase activity" EXACT [EC:1.11.1.2] +synonym: "NADPH:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.2] +synonym: "nicotinamide adenine dinucleotide phosphate peroxidase activity" EXACT [EC:1.11.1.2] +synonym: "TPN peroxidase activity" EXACT [EC:1.11.1.2] +synonym: "TPNH peroxidase activity" EXACT [EC:1.11.1.2] +synonym: "triphosphopyridine nucleotide peroxidase activity" EXACT [EC:1.11.1.2] +xref: EC:1.11.1.2 +xref: KEGG_REACTION:R00113 +xref: MetaCyc:NADPH-PEROXIDASE-RXN +xref: RHEA:15173 +is_a: GO:0004601 ! peroxidase activity + +[Term] +id: GO:0050138 +name: nicotinate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH." [EC:1.17.1.5, RHEA:12236] +synonym: "nicotinate hydroxylase activity" EXACT [EC:1.17.1.5] +synonym: "nicotinate:NADP+ 6-oxidoreductase (hydroxylating)" EXACT [EC:1.17.1.5] +synonym: "nicotinic acid hydroxylase activity" EXACT [EC:1.17.1.5] +xref: EC:1.17.1.5 +xref: KEGG_REACTION:R01720 +xref: MetaCyc:NICOTINATE-DEHYDROGENASE-RXN +xref: MetaCyc:RXN-7637 +xref: RHEA:12236 +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0050139 +name: nicotinate-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP." [EC:2.4.1.196, RHEA:19437] +synonym: "nicotinate glucosyltransferase activity" BROAD [] +synonym: "UDP-glucose:nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] +synonym: "UDP-glucose:nicotinic acid-N-glucosyltransferase activity" EXACT [EC:2.4.1.196] +synonym: "UDPglucose:nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] +synonym: "uridine diphosphoglucose-nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] +xref: EC:2.4.1.196 +xref: KEGG_REACTION:R01722 +xref: MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:19437 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050140 +name: nitrate reductase (cytochrome) activity +namespace: molecular_function +def: "Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite." [EC:1.9.6.1, MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN] +synonym: "benzyl viologen-nitrate reductase activity" EXACT [EC:1.9.6.1] +synonym: "ferrocytochrome:nitrate oxidoreductase activity" EXACT [EC:1.9.6.1] +xref: EC:1.9.6.1 +xref: MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN +is_a: GO:0016677 ! oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor + +[Term] +id: GO:0050141 +name: nitroethane oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2." [EC:1.7.3.1, MetaCyc:NITROETHANE-OXIDASE-RXN] +synonym: "nitroethane reductase activity" EXACT [EC:1.7.3.1] +synonym: "nitroethane:oxygen oxidoreductase activity" EXACT [EC:1.7.3.1] +xref: EC:1.7.3.1 +xref: MetaCyc:NITROETHANE-OXIDASE-RXN +is_a: GO:0052664 ! nitroalkane oxidase activity + +[Term] +id: GO:0050142 +name: nitrogenase (flavodoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate." [EC:1.19.6.1, MetaCyc:NITROGENASE-FLAVODOXIN-RXN] +synonym: "reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing)" EXACT [EC:1.19.6.1] +xref: EC:1.19.6.1 +xref: MetaCyc:NITROGENASE-FLAVODOXIN-RXN +is_a: GO:0016738 ! oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor + +[Term] +id: GO:0050143 +name: nocardicin-A epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: isonocardicin A = nocardicin A." [EC:5.1.1.14, RHEA:22792] +synonym: "isonocardicin A epimerase activity" EXACT [EC:5.1.1.14] +xref: EC:5.1.1.14 +xref: KEGG_REACTION:R03073 +xref: MetaCyc:NOCARDICIN-A-EPIMERASE-RXN +xref: RHEA:22792 +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives + +[Term] +id: GO:0050144 +name: nucleoside deoxyribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1." [EC:2.4.2.6, MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN] +synonym: "deoxyribose transferase activity" EXACT [EC:2.4.2.6] +synonym: "nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)" RELATED [EC:2.4.2.6] +synonym: "nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]" RELATED [EC:2.4.2.6] +synonym: "nucleoside trans-N-deoxyribosylase activity" EXACT [EC:2.4.2.6] +synonym: "nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.6] +synonym: "purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity" EXACT [EC:2.4.2.6] +synonym: "trans-deoxyribosylase activity" EXACT [EC:2.4.2.6] +synonym: "trans-N-deoxyribosylase activity" EXACT [EC:2.4.2.6] +synonym: "trans-N-glycosidase activity" EXACT [EC:2.4.2.6] +xref: EC:2.4.2.6 +xref: MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0050145 +name: nucleoside monophosphate kinase activity +namespace: molecular_function +alt_id: GO:0019201 +def: "Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate." [GOC:ai, ISBN:0198506732] +synonym: "ATP:nucleoside-phosphate phosphotransferase activity" EXACT [EC:2.7.4.4] +synonym: "NMP-kinase activity" EXACT [EC:2.7.4.4] +synonym: "nucleoside monophosphate kinase activity" EXACT [GOC:dph, GOC:tb] +synonym: "nucleoside-phosphate kinase activity" EXACT [] +synonym: "nucleotide kinase activity" RELATED [] +xref: EC:2.7.4.4 +xref: MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN +xref: Reactome:R-HSA-2162092 "carbovir monophosphate + ATP => carbovir diphosphate + ADP" +xref: Reactome:R-HSA-6788798 "AK4 phosphorylates (d)NMPs to (d)NDPs" +xref: Reactome:R-HSA-6788810 "AK6 phosphorylates (d)NMPs to (d)NDPs" +xref: Reactome:R-HSA-73548 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1)" +xref: Reactome:R-HSA-73635 "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]" +xref: Reactome:R-HSA-75125 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)" +xref: Reactome:R-HSA-75126 "dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]" +xref: RHEA:24036 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity +relationship: part_of GO:0046940 ! nucleoside monophosphate phosphorylation + +[Term] +id: GO:0050146 +name: nucleoside phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate." [EC:2.7.1.77, MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN] +synonym: "nonspecific nucleoside phosphotransferase activity" EXACT [EC:2.7.1.77] +synonym: "nucleotide:2'-nucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] +synonym: "nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] +synonym: "nucleotide:nucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] +xref: EC:2.7.1.77 +xref: MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN +xref: Reactome:R-HSA-2162066 "carbovir + IMP => carbovir monophosphate + inosine" +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity + +[Term] +id: GO:0050147 +name: nucleoside ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1." [EC:2.4.2.5, MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN] +synonym: "nucleoside N-ribosyltransferase activity" EXACT [EC:2.4.2.5] +synonym: "nucleoside:purine(pyrimidine) D-ribosyltransferase activity" EXACT [EC:2.4.2.5] +xref: EC:2.4.2.5 +xref: MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0050148 +name: nucleotide diphosphokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate." [EC:2.7.6.4, MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN] +synonym: "ATP nucleotide 3'-pyrophosphokinase activity" EXACT [EC:2.7.6.4] +synonym: "ATP:nucleoside-5'-phosphate diphosphotransferase activity" EXACT [EC:2.7.6.4] +synonym: "ATP:nucleotide pyrophosphotransferase activity" EXACT [EC:2.7.6.4] +synonym: "nucleotide 3'-pyrophosphokinase activity" EXACT [EC:2.7.6.4] +synonym: "nucleotide pyrophosphokinase activity" EXACT [] +xref: EC:2.7.6.4 +xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN +is_a: GO:0016778 ! diphosphotransferase activity + +[Term] +id: GO:0050149 +name: o-aminophenol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O." [EC:1.10.3.4, MetaCyc:O-AMINOPHENOL-OXIDASE-RXN] +synonym: "2-aminophenol:O2 oxidoreductase activity" EXACT [EC:1.10.3.4] +synonym: "2-aminophenol:oxygen oxidoreductase activity" EXACT [EC:1.10.3.4] +synonym: "GriF" RELATED [EC:1.10.3.4] +synonym: "isophenoxazine synthase activity" EXACT [EC:1.10.3.4] +synonym: "o-aminophenol:O2 oxidoreductase activity" EXACT [EC:1.10.3.4] +xref: EC:1.10.3.4 +xref: MetaCyc:O-AMINOPHENOL-OXIDASE-RXN +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0050150 +name: o-pyrocatechuate decarboxylase activity +namespace: molecular_function +alt_id: GO:0018790 +def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2)." [EC:4.1.1.46, RHEA:21492] +synonym: "2,3-DHBA decarboxylase activity" EXACT [EC:4.1.1.46] +synonym: "2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)" EXACT [EC:4.1.1.46] +synonym: "2,3-dihydroxybenzoate carboxy-lyase activity" EXACT [EC:4.1.1.46] +synonym: "2,3-dihydroxybenzoate decarboxylase activity" EXACT [] +synonym: "2,3-dihydroxybenzoic acid decarboxylase activity" EXACT [EC:4.1.1.46] +xref: EC:4.1.1.46 +xref: KEGG_REACTION:R00821 +xref: MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN +xref: RHEA:21492 +xref: UM-BBD_reactionID:r0579 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050151 +name: oleate hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate." [EC:4.2.1.53, RHEA:21852] +synonym: "(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)" EXACT [EC:4.2.1.53] +synonym: "(R)-10-hydroxystearate 10-hydro-lyase activity" EXACT [EC:4.2.1.53] +xref: EC:4.2.1.53 +xref: KEGG_REACTION:R02813 +xref: MetaCyc:OLEATE-HYDRATASE-RXN +xref: RHEA:21852 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050152 +name: omega-amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3." [EC:3.5.1.3, MetaCyc:OMEGA-AMIDASE-RXN] +synonym: "alpha-keto acid-omega-amidase activity" EXACT [EC:3.5.1.3] +synonym: "omega-amidodicarboxylate amidohydrolase activity" EXACT [EC:3.5.1.3] +synonym: "w-amidase activity" EXACT [] +xref: EC:3.5.1.3 +xref: MetaCyc:OMEGA-AMIDASE-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050153 +name: omega-hydroxydecanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH." [EC:1.1.1.66, RHEA:20880] +synonym: "10-hydroxydecanoate:NAD+ 10-oxidoreductase activity" EXACT [EC:1.1.1.66] +synonym: "w-hydroxydecanoate dehydrogenase activity" EXACT [] +xref: EC:1.1.1.66 +xref: KEGG_REACTION:R03886 +xref: MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN +xref: RHEA:20880 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050154 +name: opheline kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+)." [EC:2.7.3.7, RHEA:17553] +synonym: "ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity" EXACT [EC:2.7.3.7] +xref: EC:2.7.3.7 +xref: KEGG_REACTION:R04388 +xref: MetaCyc:OPHELINE-KINASE-RXN +xref: RHEA:17553 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0050155 +name: ornithine(lysine) transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate." [MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN, RHEA:23792] +synonym: "L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity" EXACT [] +synonym: "L-ornithine:2-oxoglutarate-aminotransferase activity" EXACT [] +synonym: "lysine/ornithine:2-oxoglutarate aminotransferase activity" EXACT [] +synonym: "ornithine(lysine) aminotransferase activity" EXACT [] +xref: EC:2.6.1.13 +xref: MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN +xref: RHEA:23792 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050156 +name: ornithine N-benzoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+)." [EC:2.3.1.127, RHEA:16929] +synonym: "benzoyl-CoA:L-ornithine N-benzoyltransferase activity" EXACT [EC:2.3.1.127] +synonym: "ornithine N-acyltransferase activity" EXACT [EC:2.3.1.127] +xref: EC:2.3.1.127 +xref: KEGG_REACTION:R00664 +xref: MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN +xref: RHEA:16929 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050157 +name: ornithine racemase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithine = D-ornithine." [EC:5.1.1.12, MetaCyc:ORNITHINE-RACEMASE-RXN] +xref: EC:5.1.1.12 +xref: MetaCyc:ORNITHINE-RACEMASE-RXN +xref: RHEA:11584 +is_a: GO:0047661 ! amino-acid racemase activity + +[Term] +id: GO:0050158 +name: orotate reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate." [EC:1.3.1.15, RHEA:14861] +synonym: "(S)-dihydroorotate:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.15] +synonym: "dihydro-orotic dehydrogenase activity" EXACT [EC:1.3.1.15] +synonym: "L-5,6-dihydro-orotate:NAD oxidoreductase activity" EXACT [EC:1.3.1.15] +synonym: "orotate reductase activity" EXACT [EC:1.3.1.15] +xref: EC:1.3.1.15 +xref: KEGG_REACTION:R01866 +xref: MetaCyc:OROTATE-REDUCTASE-NADPH-RXN +xref: RHEA:14861 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050159 +name: orsellinate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol." [EC:4.1.1.58, RHEA:16733] +synonym: "orsellinate carboxy-lyase (orcinol-forming)" EXACT [EC:4.1.1.58] +synonym: "orsellinate carboxy-lyase activity" EXACT [EC:4.1.1.58] +xref: EC:4.1.1.58 +xref: KEGG_REACTION:R02831 +xref: MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN +xref: RHEA:16733 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050160 +name: orsellinate-depside hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+)." [EC:3.1.1.40, RHEA:19549] +synonym: "lecanorate hydrolase activity" EXACT [EC:3.1.1.40] +xref: EC:3.1.1.40 +xref: KEGG_REACTION:R00054 +xref: MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN +xref: RHEA:19549 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050161 +name: succinyl-CoA:oxalate CoA-transferase +namespace: molecular_function +def: "Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate." [EC:2.8.3.2, RHEA:23588] +synonym: "oxalate CoA-transferase activity" EXACT [EC:2.8.3.2] +synonym: "oxalate coenzyme A-transferase activity" EXACT [EC:2.8.3.2] +synonym: "succinyl-beta-ketoacyl-CoA transferase activity" EXACT [EC:2.8.3.2] +synonym: "succinyl-CoA:oxalate CoA-transferase activity" EXACT [EC:2.8.3.2] +xref: EC:2.8.3.2 +xref: KEGG_REACTION:R01559 +xref: MetaCyc:OXALATE-COA-TRANSFERASE-RXN +xref: RHEA:23588 +is_a: GO:0008410 ! CoA-transferase activity + +[Term] +id: GO:0050162 +name: oxalate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2)." [EC:1.2.3.4, RHEA:21881] +synonym: "aero-oxalo dehydrogenase activity" EXACT [EC:1.2.3.4] +synonym: "oxalate:oxygen oxidoreductase activity" EXACT [EC:1.2.3.4] +synonym: "oxalic acid oxidase activity" EXACT [EC:1.2.3.4] +xref: EC:1.2.3.4 +xref: KEGG_REACTION:R00273 +xref: MetaCyc:OXALATE-OXIDASE-RXN +xref: RHEA:21881 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0050163 +name: oxaloacetate tautomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: oxaloacetate = enol-oxaloacetate." [EC:5.3.2.2, RHEA:16021] +synonym: "oxalacetic keto-enol isomerase activity" EXACT [EC:5.3.2.2] +synonym: "oxaloacetate keto-enol tautomerase activity" EXACT [EC:5.3.2.2] +synonym: "oxaloacetate keto-enol-isomerase activity" EXACT [EC:5.3.2.2] +xref: EC:5.3.2.2 +xref: KEGG_REACTION:R00363 +xref: MetaCyc:OXALOACETATE-TAUTOMERASE-RXN +xref: RHEA:16021 +is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups + +[Term] +id: GO:0050164 +name: oxoglutarate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA." [EC:1.2.1.52, RHEA:21400] +synonym: "2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating)" EXACT [EC:1.2.1.52] +xref: EC:1.2.1.52 +xref: KEGG_REACTION:R00265 +xref: MetaCyc:OXOGLUTARATE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:21400 +is_a: GO:0034601 ! oxoglutarate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0050165 +name: pantetheine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate." [EC:2.7.1.34, MetaCyc:PANTETHEINE-KINASE-RXN] +synonym: "ATP:pantetheine 4'-phosphotransferase activity" EXACT [EC:2.7.1.34] +synonym: "pantetheine kinase (phosphorylating)" EXACT [EC:2.7.1.34] +xref: EC:2.7.1.34 +xref: MetaCyc:PANTETHEINE-KINASE-RXN +xref: RHEA:22472 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050166 +name: pantoate 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH." [EC:1.1.1.106, RHEA:23000] +synonym: "(R)-pantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.106] +synonym: "D-pantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.106] +synonym: "panthothenase activity" EXACT [EC:1.1.1.106] +synonym: "pantoate dehydrogenase activity" EXACT [EC:1.1.1.106] +xref: EC:1.1.1.106 +xref: KEGG_REACTION:R02471 +xref: MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN +xref: RHEA:23000 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050167 +name: pantothenoylcysteine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2)." [EC:4.1.1.30, RHEA:15077] +synonym: "N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.30] +synonym: "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)" EXACT [EC:4.1.1.30] +synonym: "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.30] +synonym: "pantothenylcysteine decarboxylase activity" EXACT [EC:4.1.1.30] +xref: EC:4.1.1.30 +xref: KEGG_REACTION:R02972 +xref: MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN +xref: RHEA:15077 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050168 +name: pentanamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate." [EC:3.5.1.50, RHEA:10000] +synonym: "pentanamide amidohydrolase activity" EXACT [EC:3.5.1.50] +synonym: "valeramidase activity" EXACT [EC:3.5.1.50] +xref: EC:3.5.1.50 +xref: KEGG_REACTION:R02938 +xref: MetaCyc:PENTANAMIDASE-RXN +xref: RHEA:10000 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050169 +name: peptide-tryptophan 2,3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine." [EC:1.13.11.26, MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN, PMID:4403729] +synonym: "peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.26] +synonym: "peptidyltryptophan 2,3-dioxygenase activity" EXACT [EC:1.13.11.26] +synonym: "pyrrolooxygenase activity" EXACT [EC:1.13.11.26] +synonym: "tryptophan pyrrolooxygenase activity" EXACT [EC:1.13.11.26] +xref: EC:1.13.11.26 +xref: MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0050170 +name: peptidyl-glutaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3." [EC:3.5.1.43, MetaCyc:PEPTIDYL-GLUTAMINASE-RXN] +synonym: "peptideglutaminase activity" EXACT [EC:3.5.1.43] +synonym: "peptidoglutaminase activity" EXACT [EC:3.5.1.43] +synonym: "peptidoglutaminase I activity" NARROW [EC:3.5.1.43] +synonym: "peptidyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.43] +xref: EC:3.5.1.43 +xref: MetaCyc:PEPTIDYL-GLUTAMINASE-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050171 +name: phenol beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside." [EC:2.4.1.35, MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN] +synonym: "phenol b-glucosyltransferase activity" EXACT [] +synonym: "phenol-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "UDP glucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "UDP-glucose glucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "UDP-glucose:phenol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "UDPglucose:phenol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "UDPglucosyltransferase activity" EXACT [EC:2.4.1.35] +synonym: "uridine diphosphoglucosyltransferase activity" EXACT [EC:2.4.1.35] +xref: EC:2.4.1.35 +xref: MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050172 +name: phenylalanine 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O." [EC:1.13.12.9, RHEA:10712] +synonym: "L-phenylalanine oxidase (deaminating and decarboxylating)" EXACT [EC:1.13.12.9] +synonym: "l-phenylalanine oxidase (deaminating and decarboxylating) activity" EXACT [EC:1.13.12.9] +synonym: "L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.9] +synonym: "phenylalanine (deaminating, decarboxylating) oxidase activity" EXACT [EC:1.13.12.9] +synonym: "phenylalanine (deaminating, decarboxylating)oxidase activity" EXACT [EC:1.13.12.9] +xref: EC:1.13.12.9 +xref: KEGG_REACTION:R00690 +xref: MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN +xref: RHEA:10712 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0050173 +name: phenylalanine adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+)." [EC:2.7.7.54, RHEA:17189] +synonym: "ATP:L-phenylalanine adenylyltransferase activity" EXACT [EC:2.7.7.54] +synonym: "ATP:phenylalanine adenylyltransferase activity" EXACT [] +synonym: "L-phenylalanine adenylyltransferase activity" EXACT [EC:2.7.7.54] +xref: EC:2.7.7.54 +xref: KEGG_REACTION:R00687 +xref: MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN +xref: RHEA:17189 +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0050174 +name: phenylalanine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2." [EC:4.1.1.53, MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN] +synonym: "aromatic L-amino acid decarboxylase activity" EXACT [EC:4.1.1.53] +synonym: "L-phenylalanine carboxy-lyase (phenylethylamine-forming)" EXACT [EC:4.1.1.53] +synonym: "L-phenylalanine carboxy-lyase activity" EXACT [EC:4.1.1.53] +synonym: "L-phenylalanine decarboxylase activity" EXACT [EC:4.1.1.53] +xref: EC:4.1.1.53 +xref: MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN +xref: RHEA:19717 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050175 +name: phenylalanine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH." [EC:1.4.1.20, MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN] +synonym: "L-phenylalanine dehydrogenase activity" EXACT [EC:1.4.1.20] +synonym: "L-phenylalanine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.20] +synonym: "PHD" RELATED [EC:1.4.1.20] +synonym: "PheDH activity" EXACT [EC:1.4.1.20] +xref: EC:1.4.1.20 +xref: MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN +xref: RHEA:21408 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050176 +name: phenylalanine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+)." [EC:2.3.1.53, RHEA:17801] +synonym: "acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.53] +synonym: "acetyl-CoA:L-phenylalanine N-acetyltransferase activity" EXACT [EC:2.3.1.53] +xref: EC:2.3.1.53 +xref: KEGG_REACTION:R00693 +xref: MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN +xref: RHEA:17801 +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0050177 +name: phenylpyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2." [EC:4.1.1.43, MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN] +synonym: "phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)" EXACT [EC:4.1.1.43] +synonym: "phenylpyruvate carboxy-lyase activity" EXACT [EC:4.1.1.43] +xref: EC:4.1.1.43 +xref: MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN +xref: RHEA:14185 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050178 +name: phenylpyruvate tautomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate." [EC:5.3.2.1, MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN] +synonym: "phenylpyruvate keto--enol tautomerase activity" EXACT [EC:5.3.2.1] +synonym: "phenylpyruvate keto-enol-isomerase activity" EXACT [EC:5.3.2.1] +synonym: "phenylpyruvic keto--enol isomerase activity" EXACT [EC:5.3.2.1] +xref: EC:5.3.2.1 +xref: MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN +xref: RHEA:17097 +is_a: GO:0016862 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups + +[Term] +id: GO:0050179 +name: phenylserine aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine." [EC:4.1.2.26, RHEA:21712] +synonym: "L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)" EXACT [EC:4.1.2.26] +synonym: "L-threo-3-phenylserine benzaldehyde-lyase activity" EXACT [EC:4.1.2.26] +xref: EC:4.1.2.26 +xref: KEGG_REACTION:R01766 +xref: MetaCyc:PHENYLSERINE-ALDOLASE-RXN +xref: RHEA:21712 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050180 +name: phloretin hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol." [EC:3.7.1.4, RHEA:23396] +synonym: "2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity" EXACT [EC:3.7.1.4] +synonym: "lactase-phlorizin hydrolase" BROAD [EC:3.7.1.4] +xref: EC:3.7.1.4 +xref: KEGG_REACTION:R02901 +xref: MetaCyc:PHLORETIN-HYDROLASE-RXN +xref: RHEA:23396 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0050181 +name: phorbol-diester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate." [EC:3.1.1.51, RHEA:21316] +synonym: "12,13-diacylphorbate 12-acylhydrolase activity" EXACT [EC:3.1.1.51] +synonym: "diacylphorbate 12-hydrolase activity" EXACT [EC:3.1.1.51] +synonym: "PDEH" RELATED [EC:3.1.1.51] +synonym: "phorbol-12,13-diester 12-ester hydrolase activity" EXACT [EC:3.1.1.51] +xref: EC:3.1.1.51 +xref: KEGG_REACTION:R04119 +xref: MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN +xref: RHEA:21316 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050182 +name: phosphate butyryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA." [EC:2.3.1.19, RHEA:20892] +synonym: "butanoyl-CoA:phosphate butanoyltransferase activity" EXACT [EC:2.3.1.19] +synonym: "phosphotransbutyrylase activity" EXACT [EC:2.3.1.19] +xref: EC:2.3.1.19 +xref: KEGG_REACTION:R01174 +xref: MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN +xref: RHEA:20892 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050183 +name: phosphatidylcholine 12-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+)." [EC:1.14.18.4, RHEA:46360] +synonym: "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)" EXACT [EC:1.14.18.4] +synonym: "oleate D12-hydroxylase activity" EXACT [] +synonym: "oleate Delta(12)-hydroxylase activity" EXACT [EC:1.14.18.4] +synonym: "oleate delta12-hydroxylase activity" EXACT [EC:1.14.18.4] +synonym: "oleate delta12-monooxygenase activity" EXACT [EC:1.14.18.4] +synonym: "ricinoleic acid synthase activity" EXACT [EC:1.14.18.4] +xref: EC:1.14.18.4 +xref: KEGG_REACTION:R03476 +xref: MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN +xref: RHEA:46360 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050184 +name: phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH." [RHEA:12564] +synonym: "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity" RELATED [] +synonym: "acyl-lipid omega-6 desaturase (cytochrome b5)" RELATED [EC:1.14.19.22] +synonym: "linoleate synthase activity" RELATED [EC:1.14.19.22] +synonym: "oleate desaturase activity" RELATED [EC:1.14.19.22] +synonym: "oleoyl-CoA desaturase activity" RELATED [EC:1.14.19.22] +synonym: "oleoylphosphatidylcholine desaturase activity" RELATED [] +xref: EC:1.14.19.22 +xref: KEGG_REACTION:R03475 +xref: MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN +xref: RHEA:12564 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050185 +name: phosphatidylinositol deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+)." [EC:3.1.1.52, RHEA:18001] +synonym: "1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity" EXACT [EC:3.1.1.52] +synonym: "phosphatidylinositol phospholipase A2 activity" EXACT [EC:3.1.1.52] +xref: EC:3.1.1.52 +xref: KEGG_REACTION:R03360 +xref: MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN +xref: RHEA:18001 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050186 +name: phosphoadenylylsulfatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate." [EC:3.6.2.2, MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN] +synonym: "3'-phosphoadenylylsulfate sulfohydrolase activity" EXACT [EC:3.6.2.2] +synonym: "3-phosphoadenosine 5-phosphosulfate sulfatase activity" EXACT [EC:3.6.2.2] +synonym: "3-phosphoadenylyl sulfatase activity" EXACT [EC:3.6.2.2] +synonym: "PAPS sulfatase activity" EXACT [EC:3.6.2.2] +synonym: "phosphoadenylylsulphatase activity" EXACT [] +xref: EC:3.6.2.2 +xref: MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN +xref: RHEA:11232 +is_a: GO:0016819 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides + +[Term] +id: GO:0050187 +name: phosphoamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate." [EC:3.9.1.1, RHEA:12977] +synonym: "creatine phosphatase activity" EXACT [EC:3.9.1.1] +synonym: "phosphamide hydrolase activity" EXACT [EC:3.9.1.1] +xref: EC:3.9.1.1 +xref: KEGG_REACTION:R01882 +xref: MetaCyc:PHOSPHOAMIDASE-RXN +xref: RHEA:12977 +is_a: GO:0016825 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds + +[Term] +id: GO:0050188 +name: phosphoenolpyruvate mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate." [EC:5.4.2.9, RHEA:17013] +synonym: "PEP mutase activity" EXACT [EC:5.4.2.9] +synonym: "PEP phosphomutase activity" EXACT [EC:5.4.2.9] +synonym: "PEPPM" RELATED [EC:5.4.2.9] +synonym: "phosphoenolpyruvate 2,3-phosphonomutase activity" EXACT [EC:5.4.2.9] +synonym: "phosphoenolpyruvate phosphomutase activity" EXACT [EC:5.4.2.9] +synonym: "phosphoenolpyruvate-phosphonopyruvate phosphomutase activity" EXACT [EC:5.4.2.9] +xref: EC:5.4.2.9 +xref: KEGG_REACTION:R00661 +xref: MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN +xref: RHEA:17013 +is_a: GO:0016868 ! intramolecular transferase activity, phosphotransferases + +[Term] +id: GO:0050189 +name: phosphoenolpyruvate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate." [EC:3.1.3.60, RHEA:19997] +synonym: "PEP phosphatase activity" EXACT [EC:3.1.3.60] +synonym: "phosphoenolpyruvate phosphohydrolase activity" EXACT [EC:3.1.3.60] +xref: EC:3.1.3.60 +xref: KEGG_REACTION:R00208 +xref: MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN +xref: RHEA:19997 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050190 +name: phosphoglucokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.10, RHEA:13377] +synonym: "ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.10] +synonym: "ATP:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.10] +synonym: "glucose-phosphate kinase activity" EXACT [EC:2.7.1.10] +synonym: "phosphoglucokinase (phosphorylating)" EXACT [EC:2.7.1.10] +xref: EC:2.7.1.10 +xref: KEGG_REACTION:R00949 +xref: MetaCyc:PHOSPHOGLUCOKINASE-RXN +xref: RHEA:13377 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050191 +name: phosphoglycerate kinase (GTP) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+)." [EC:2.7.2.10, RHEA:23332] +synonym: "GTP:3-phospho-D-glycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.10] +xref: EC:2.7.2.10 +xref: KEGG_REACTION:R01517 +xref: MetaCyc:PHOSPHOGLYCERATE-KINASE-GTP-RXN +xref: RHEA:23332 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016774 ! phosphotransferase activity, carboxyl group as acceptor + +[Term] +id: GO:0050192 +name: phosphoglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate." [EC:3.1.3.20, RHEA:21156] +synonym: "D-2-phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.20] +synonym: "D-glycerate-2-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.20] +synonym: "glycerophosphate phosphatase activity" EXACT [EC:3.1.3.20] +xref: EC:3.1.3.20 +xref: KEGG_REACTION:R01748 +xref: MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN +xref: RHEA:21156 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050193 +name: phosphoketolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O." [EC:4.1.2.9, MetaCyc:PHOSPHOKETOLASE-RXN] +synonym: "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)" EXACT [EC:4.1.2.9] +synonym: "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity" EXACT [EC:4.1.2.9] +synonym: "xylulose-5-phosphate phosphoketolase activity" EXACT [EC:4.1.2.9] +xref: EC:4.1.2.9 +xref: MetaCyc:PHOSPHOKETOLASE-RXN +xref: RHEA:10468 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050194 +name: phosphonoacetaldehyde hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate." [EC:3.11.1.1, RHEA:18905] +synonym: "2-oxoethylphosphonate phosphonohydrolase activity" EXACT [EC:3.11.1.1] +synonym: "2-phosphonoacetylaldehyde phosphonohydrolase activity" EXACT [EC:3.11.1.1] +synonym: "phosphonatase activity" EXACT [EC:3.11.1.1] +synonym: "phosphonoacetylaldehyde phosphonohydrolase activity" EXACT [EC:3.11.1.1] +xref: EC:3.11.1.1 +xref: KEGG_REACTION:R00747 +xref: MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN +xref: RHEA:18905 +is_a: GO:0016827 ! hydrolase activity, acting on acid carbon-phosphorus bonds + +[Term] +id: GO:0050195 +name: phosphoribokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+)." [EC:2.7.1.18, RHEA:21216] +synonym: "ATP:D-ribose-5-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.18] +synonym: "phosphoribokinase (phosphorylating)" EXACT [EC:2.7.1.18] +xref: EC:2.7.1.18 +xref: KEGG_REACTION:R01050 +xref: MetaCyc:PHOSPHORIBOKINASE-RXN +xref: RHEA:21216 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050196 +name: [phosphorylase] phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate." [EC:3.1.3.17, MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN] +synonym: "glycogen phosphorylase phosphatase activity" EXACT [EC:3.1.3.17] +synonym: "phosphorylase a phosphatase activity" EXACT [EC:3.1.3.17] +synonym: "phosphorylase a phosphohydrolase activity" EXACT [EC:3.1.3.17] +synonym: "phosphorylase phosphatase activity" EXACT [] +synonym: "PR-enzyme" RELATED [EC:3.1.3.17] +synonym: "protein phosphatase C" RELATED [EC:3.1.3.17] +synonym: "type 1 protein phosphatase activity" EXACT [EC:3.1.3.17] +xref: EC:3.1.3.17 +xref: MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0050197 +name: phytanate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA." [EC:6.2.1.24, RHEA:21380] +synonym: "phytanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.24] +synonym: "phytanoyl-CoA ligase activity" EXACT [EC:6.2.1.24] +xref: EC:6.2.1.24 +xref: KEGG_REACTION:R03631 +xref: MetaCyc:PHYTANATE--COA-LIGASE-RXN +xref: Reactome:R-HSA-389622 "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate" +xref: RHEA:21380 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0050198 +name: pinosylvin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin." [EC:2.3.1.146, RHEA:12552] +synonym: "malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.146] +synonym: "pine stilbene synthase activity" EXACT [EC:2.3.1.146] +synonym: "stilbene synthase activity" BROAD [EC:2.3.1.146] +xref: EC:2.3.1.146 +xref: KEGG_REACTION:R02505 +xref: MetaCyc:PINOSYLVIN-SYNTHASE-RXN +xref: RHEA:12552 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050199 +name: piperidine N-piperoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+)." [EC:2.3.1.145, RHEA:14561] +synonym: "(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity" EXACT [EC:2.3.1.145] +synonym: "piperidine piperoyltransferase activity" EXACT [EC:2.3.1.145] +synonym: "piperoyl-CoA:piperidine N-piperoyltransferase activity" EXACT [EC:2.3.1.145] +xref: EC:2.3.1.145 +xref: KEGG_REACTION:R03994 +xref: MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN +xref: RHEA:14561 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050200 +name: plasmalogen synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine." [EC:2.3.1.25, MetaCyc:PLASMALOGEN-SYNTHASE-RXN] +synonym: "1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity" EXACT [EC:2.3.1.25] +synonym: "acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity" EXACT [EC:2.3.1.25] +synonym: "lysoplasmenylcholine acyltransferase activity" EXACT [EC:2.3.1.25] +synonym: "O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity" EXACT [EC:2.3.1.25] +xref: EC:2.3.1.25 +xref: MetaCyc:PLASMALOGEN-SYNTHASE-RXN +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050201 +name: fucokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+)." [EC:2.7.1.52, RHEA:13241] +synonym: "ATP:6-deoxy-L-galactose 1-phosphotransferase activity" EXACT [EC:2.7.1.52] +synonym: "ATP:beta-L-fucose 1-phosphotransferase activity" EXACT [EC:2.7.1.52] +synonym: "fucokinase (phosphorylating) activity" EXACT [EC:2.7.1.52] +synonym: "fucose kinase activity" EXACT [EC:2.7.1.52] +synonym: "L-fucokinase activity" EXACT [EC:2.7.1.52] +synonym: "L-fucose kinase activity" EXACT [EC:2.7.1.52] +xref: EC:2.7.1.52 +xref: KEGG_REACTION:R03161 +xref: MetaCyc:FUCOKINASE-RXN +xref: Reactome:R-HSA-6787540 "FUK phosphorylates beta-Fuc to Fuc1P" +xref: RHEA:13241 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050202 +name: octopamine dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+)." [EC:4.2.1.87, RHEA:18173] +synonym: "octopamine hydro-lyase (deaminating)" EXACT [EC:4.2.1.87] +synonym: "octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]" RELATED [EC:4.2.1.87] +synonym: "octopamine hydrolyase activity" EXACT [EC:4.2.1.87] +xref: EC:4.2.1.87 +xref: KEGG_REACTION:R03358 +xref: MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN +xref: RHEA:18173 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050203 +name: oxalate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA." [EC:6.2.1.8, RHEA:18293] +synonym: "oxalate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.8] +synonym: "oxalyl coenzyme A synthetase activity" EXACT [EC:6.2.1.8] +synonym: "oxalyl-CoA synthetase activity" EXACT [EC:6.2.1.8] +xref: EC:6.2.1.8 +xref: KEGG_REACTION:R01558 +xref: MetaCyc:OXALATE--COA-LIGASE-RXN +xref: RHEA:18293 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0050204 +name: oxalomalate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate." [EC:4.1.3.13, RHEA:22032] +synonym: "3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)" EXACT [EC:4.1.3.13] +synonym: "3-oxalomalate glyoxylate-lyase activity" EXACT [EC:4.1.3.13] +xref: EC:4.1.3.13 +xref: KEGG_REACTION:R00477 +xref: MetaCyc:OXALOMALATE-LYASE-RXN +xref: RHEA:22032 +is_a: GO:0016833 ! oxo-acid-lyase activity + +[Term] +id: GO:0050205 +name: oxamate carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate." [EC:2.1.3.5, RHEA:22984] +synonym: "carbamoyl-phosphate:oxamate carbamoyltransferase activity" EXACT [EC:2.1.3.5] +synonym: "oxamic transcarbamylase activity" EXACT [EC:2.1.3.5] +xref: EC:2.1.3.5 +xref: KEGG_REACTION:R02937 +xref: MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN +xref: RHEA:22984 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0050206 +name: oximinotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate." [EC:2.6.3.1, RHEA:11624] +synonym: "oximase activity" EXACT [EC:2.6.3.1] +synonym: "pyruvate-acetone oximinotransferase activity" EXACT [EC:2.6.3.1] +synonym: "pyruvate-oxime:acetone oximinotransferase activity" EXACT [EC:2.6.3.1] +synonym: "transoximase activity" EXACT [EC:2.6.3.1] +synonym: "transoximinase activity" EXACT [EC:2.6.3.1] +xref: EC:2.6.3.1 +xref: KEGG_REACTION:R03796 +xref: MetaCyc:OXIMINOTRANSFERASE-RXN +xref: RHEA:11624 +is_a: GO:0016770 ! oximinotransaminase activity + +[Term] +id: GO:0050207 +name: plasmanylethanolamine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O." [EC:1.14.99.19, MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN] +synonym: "1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity" EXACT [EC:1.14.99.19] +synonym: "1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity" EXACT [EC:1.14.99.19] +synonym: "alkylacylglycero-phosphorylethanolamine dehydrogenase activity" EXACT [EC:1.14.99.19] +synonym: "alkylacylglycerophosphoethanolamine desaturase activity" EXACT [EC:1.14.99.19] +synonym: "dehydrogenase, alkyl-acylglycerophosphorylethanolamine" EXACT [EC:1.14.99.19] +synonym: "O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.19] +synonym: "plasmenylethanolamine desaturase activity" EXACT [] +xref: EC:1.14.99.19 +xref: MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN +xref: RHEA:22956 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050208 +name: polysialic-acid O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9." [EC:2.3.1.136, MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN] +synonym: "acetyl-CoA:polysialic-acid O-acetyltransferase activity" EXACT [EC:2.3.1.136] +synonym: "lecithin retinol acyl transferase activity" EXACT [EC:2.3.1.136] +synonym: "lecithin:retinol acyltransferase activity" EXACT [EC:2.3.1.136] +synonym: "LRAT" RELATED [EC:2.3.1.136] +synonym: "retinyl ester synthase activity" EXACT [EC:2.3.1.136] +xref: EC:2.3.1.136 +xref: MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050209 +name: polyvinyl-alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2." [EC:1.1.3.30, MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN] +synonym: "dehydrogenase, polyvinyl alcohol" EXACT [EC:1.1.3.30] +synonym: "polyvinyl-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.30] +synonym: "PVA oxidase activity" EXACT [EC:1.1.3.30] +xref: EC:1.1.3.30 +xref: MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050210 +name: prenyl-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate." [EC:3.1.7.1, MetaCyc:PRENYL-PYROPHOSPHATASE-RXN] +synonym: "prenol pyrophosphatase activity" EXACT [EC:3.1.7.1] +synonym: "prenyl-diphosphate diphosphohydrolase activity" EXACT [EC:3.1.7.1] +synonym: "prenyl-pyrophosphatase activity" EXACT [] +synonym: "prenylphosphatase activity" EXACT [EC:3.1.7.1] +xref: EC:3.1.7.1 +xref: MetaCyc:PRENYL-PYROPHOSPHATASE-RXN +xref: RHEA:21496 +is_a: GO:0016794 ! diphosphoric monoester hydrolase activity + +[Term] +id: GO:0050211 +name: procollagen galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine." [EC:2.4.1.50, MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN] +synonym: "collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "collagen hydroxylysyl galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "hydroxylysine galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "UDP galactose-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity" EXACT [EC:2.4.1.50] +synonym: "uridine diphosphogalactose-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] +xref: EC:2.4.1.50 +xref: MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN +xref: Reactome:R-HSA-1981120 "Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2." +xref: Reactome:R-HSA-1981128 "Galactosylation of collagen propeptide hydroxylysines by PLOD3" +is_a: GO:0035250 ! UDP-galactosyltransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0050212 +name: progesterone 11-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O." [EC:1.14.99.14, RHEA:18205] +synonym: "progesterone 11-alpha-hydroxylase activity" EXACT [EC:1.14.99.14] +synonym: "progesterone 11a-monooxygenase activity" EXACT [] +synonym: "progesterone 11alpha-hydroxylase activity" EXACT [EC:1.14.99.14] +synonym: "progesterone 11alpha-monooxygenase activity" EXACT [EC:1.14.99.14] +synonym: "progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)" EXACT [EC:1.14.99.14] +xref: EC:1.14.99.14 +xref: KEGG_REACTION:R02214 +xref: MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN +xref: RHEA:18205 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050213 +name: progesterone 5-alpha-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH." [EC:1.3.1.30, MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN] +synonym: "5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity" EXACT [EC:1.3.1.30] +synonym: "delta4-steroid 5alpha-reductase (progesterone)" EXACT [EC:1.3.1.30] +synonym: "progesterone 5a-reductase activity" EXACT [] +synonym: "progesterone 5alpha-reductase activity" EXACT [EC:1.3.1.30] +synonym: "steroid 5-alpha-reductase activity" BROAD [EC:1.3.1.30] +xref: EC:1.3.1.30 +xref: MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN +xref: RHEA:21952 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050214 +name: progesterone monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate." [EC:1.14.99.4, RHEA:11984] +synonym: "progesterone hydroxylase activity" EXACT [EC:1.14.99.4] +synonym: "progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.99.4] +xref: EC:1.14.99.4 +xref: KEGG_REACTION:R02212 +xref: MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN +xref: RHEA:11984 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050215 +name: propanediol dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal." [EC:4.2.1.28, RHEA:14569] +synonym: "1,2-propanediol dehydratase activity" EXACT [EC:4.2.1.28] +synonym: "adenosylcobalamin-dependent diol dehydratase activity" EXACT [EC:4.2.1.28] +synonym: "coenzyme B12-dependent diol dehydrase activity" EXACT [EC:4.2.1.28] +synonym: "diol dehydrase activity" EXACT [EC:4.2.1.28] +synonym: "diol dehydratase activity" EXACT [EC:4.2.1.28] +synonym: "dioldehydratase activity" EXACT [EC:4.2.1.28] +synonym: "DL-1,2-propanediol hydro-lyase activity" EXACT [EC:4.2.1.28] +synonym: "meso-2,3-butanediol dehydrase activity" EXACT [EC:4.2.1.28] +synonym: "propane-1,2-diol hydro-lyase (propanal-forming)" EXACT [EC:4.2.1.28] +synonym: "propane-1,2-diol hydro-lyase activity" EXACT [EC:4.2.1.28] +synonym: "propanediol dehydrase activity" EXACT [EC:4.2.1.28] +xref: EC:4.2.1.28 +xref: KEGG_REACTION:R02376 +xref: MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN +xref: RHEA:14569 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050216 +name: propanediol-phosphate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH." [EC:1.1.1.7, RHEA:21584] +xref: EC:1.1.1.7 +xref: KEGG_REACTION:R04236 +xref: MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN +xref: RHEA:21584 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050217 +name: propioin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal." [EC:4.1.2.35, RHEA:11100] +synonym: "4-hydroxy-3-hexanone aldolase activity" EXACT [EC:4.1.2.35] +synonym: "4-hydroxy-3-hexanone propanal-lyase (propanal-forming)" EXACT [EC:4.1.2.35] +synonym: "4-hydroxy-3-hexanone propanal-lyase activity" EXACT [EC:4.1.2.35] +xref: EC:4.1.2.35 +xref: KEGG_REACTION:R00038 +xref: MetaCyc:PROPIOIN-SYNTHASE-RXN +xref: RHEA:11100 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050218 +name: propionate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA." [EC:6.2.1.17, MetaCyc:PROPIONATE--COA-LIGASE-RXN] +synonym: "propanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.17] +synonym: "propionyl-CoA synthetase activity" EXACT [EC:6.2.1.17] +xref: EC:6.2.1.17 +xref: MetaCyc:PROPIONATE--COA-LIGASE-RXN +xref: RHEA:20373 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0050219 +name: prostaglandin-A1 delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin A1 = prostaglandin C1." [EC:5.3.3.9, RHEA:10460] +synonym: "(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity" EXACT [EC:5.3.3.9] +synonym: "prostaglandin A isomerase activity" EXACT [EC:5.3.3.9] +synonym: "prostaglandin-A1 D-isomerase activity" EXACT [] +xref: EC:5.3.3.9 +xref: KEGG_REACTION:R04565 +xref: MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN +xref: RHEA:10460 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0050220 +name: prostaglandin-E synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2)." [EC:5.3.99.3, RHEA:12893] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [EC:5.3.99.3] +synonym: "endoperoxide isomerase activity" EXACT [EC:5.3.99.3] +synonym: "PGE isomerase activity" EXACT [EC:5.3.99.3] +synonym: "PGE2 isomerase activity" EXACT [EC:5.3.99.3] +synonym: "PGH-PGE isomerase activity" EXACT [EC:5.3.99.3] +synonym: "prostaglandin endoperoxide E isomerase activity" EXACT [EC:5.3.99.3] +synonym: "prostaglandin endoperoxide E2 isomerase activity" EXACT [EC:5.3.99.3] +synonym: "prostaglandin H-E isomerase activity" EXACT [EC:5.3.99.3] +synonym: "prostaglandin R-prostaglandin E isomerase activity" EXACT [EC:5.3.99.3] +synonym: "Prostaglandin-H(2) E-isomerase activity" EXACT [EC:5.3.99.3] +synonym: "prostaglandin-H2 E-isomerase activity" EXACT [EC:5.3.99.3] +xref: EC:5.3.99.3 +xref: KEGG_REACTION:R02265 +xref: MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN +xref: Reactome:R-HSA-2161660 "PGH2 is isomerised to PGE2 by PTGES" +xref: Reactome:R-HSA-265295 "Prostaglandin E synthase isomerizes PGH2 to PGE2" +xref: RHEA:12893 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0050221 +name: prostaglandin-E2 9-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH." [EC:1.1.1.189, MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN] +synonym: "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity" EXACT [EC:1.1.1.189] +synonym: "9-keto-prostaglandin E(2) reductase activity" EXACT [EC:1.1.1.189] +synonym: "9-keto-prostaglandin E2 reductase activity" EXACT [EC:1.1.1.189] +synonym: "9-ketoprostaglandin reductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE(2) 9-ketoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE(2) 9-oxoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE-9-ketoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE2 9-ketoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE2 9-oxoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE2-9-ketoreductase activity" EXACT [EC:1.1.1.189] +synonym: "PGE2-9-OR" RELATED [EC:1.1.1.189] +synonym: "prostaglandin E 9-ketoreductase activity" EXACT [EC:1.1.1.189] +synonym: "prostaglandin E2-9-oxoreductase activity" EXACT [EC:1.1.1.189] +synonym: "prostaglandin-E(2) 9-oxoreductase activity" EXACT [EC:1.1.1.189] +synonym: "prostaglandin-E2 9-oxoreductase activity" EXACT [EC:1.1.1.189] +synonym: "reductase, 15-hydroxy-9-oxoprostaglandin" EXACT [EC:1.1.1.189] +xref: EC:1.1.1.189 +xref: MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN +xref: Reactome:R-HSA-2161651 "PGE2 is converted to PGF2a by CBR1" +xref: RHEA:24508 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050223 +name: protocatechuate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2)." [EC:4.1.1.63, RHEA:22416] +synonym: "3,4-dihydrobenzoate decarboxylase activity" EXACT [EC:4.1.1.63] +synonym: "3,4-dihydroxybenzoate carboxy-lyase (catechol-forming)" EXACT [EC:4.1.1.63] +synonym: "3,4-dihydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.63] +synonym: "protocatechuate carboxy-lyase activity" EXACT [EC:4.1.1.63] +xref: EC:4.1.1.63 +xref: KEGG_REACTION:R00822 +xref: MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN +xref: RHEA:22416 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050224 +name: prunasin beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile." [EC:3.2.1.118, RHEA:16489] +synonym: "prunasin b-glucosidase activity" EXACT [] +synonym: "prunasin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.118] +synonym: "prunasin hydrolase activity" EXACT [EC:3.2.1.118] +xref: EC:3.2.1.118 +xref: KEGG_REACTION:R02558 +xref: MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN +xref: RHEA:16489 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0050225 +name: pseudouridine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate." [EC:2.7.1.83, RHEA:22448] +synonym: "ATP:pseudouridine 5'-phosphotransferase activity" EXACT [EC:2.7.1.83] +synonym: "pseudouridine kinase (phosphorylating)" EXACT [EC:2.7.1.83] +xref: EC:2.7.1.83 +xref: KEGG_REACTION:R03315 +xref: MetaCyc:PSEUDOURIDINE-KINASE-RXN +xref: RHEA:22448 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050226 +name: psychosine sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate." [EC:2.8.2.13, MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN] +synonym: "3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity" EXACT [EC:2.8.2.13] +synonym: "3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity" EXACT [EC:2.8.2.13] +synonym: "PAPS:psychosine sulphotransferase activity" EXACT [EC:2.8.2.13] +synonym: "psychosine sulphotransferase activity" EXACT [] +xref: EC:2.8.2.13 +xref: MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050227 +name: pteridine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown." [EC:1.17.3.1, MetaCyc:PTERIDINE-OXIDASE-RXN] +synonym: "2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating)" EXACT [EC:1.17.3.1] +xref: EC:1.17.3.1 +xref: MetaCyc:PTERIDINE-OXIDASE-RXN +is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor + +[Term] +id: GO:0050228 +name: pterin deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3." [EC:3.5.4.11, MetaCyc:PTERIN-DEAMINASE-RXN] +synonym: "2-amino-4-hydroxypteridine aminohydrolase activity" EXACT [EC:3.5.4.11] +synonym: "acrasinase activity" EXACT [EC:3.5.4.11] +xref: EC:3.5.4.11 +xref: MetaCyc:PTERIN-DEAMINASE-RXN +xref: RHEA:11904 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0050229 +name: pterocarpin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH." [EC:1.1.1.246, MetaCyc:PTEROCARPIN-SYNTHASE-RXN] +synonym: "medicarpin:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.1.1.246] +synonym: "pterocarpan synthase activity" EXACT [EC:1.1.1.246] +xref: EC:1.1.1.246 +xref: MetaCyc:PTEROCARPIN-SYNTHASE-RXN +xref: RHEA:13533 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050230 +name: purine imidazole-ring cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O." [EC:4.3.2.4, MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN] +synonym: "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing)" EXACT [EC:4.3.2.4] +synonym: "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)" EXACT [EC:4.3.2.4] +synonym: "DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)" EXACT [EC:4.3.2.4] +xref: EC:4.3.2.4 +xref: MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN +is_a: GO:0009975 ! cyclase activity +is_a: GO:0016842 ! amidine-lyase activity + +[Term] +id: GO:0050231 +name: putrescine carbamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate." [EC:2.1.3.6, RHEA:21936] +synonym: "carbamoyl-phosphate:putrescine carbamoyltransferase activity" EXACT [EC:2.1.3.6] +synonym: "PTCase activity" EXACT [EC:2.1.3.6] +synonym: "putrescine synthase activity" EXACT [EC:2.1.3.6] +synonym: "putrescine transcarbamylase activity" EXACT [EC:2.1.3.6] +xref: EC:2.1.3.6 +xref: KEGG_REACTION:R01399 +xref: MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN +xref: RHEA:21936 +is_a: GO:0016743 ! carboxyl- or carbamoyltransferase activity + +[Term] +id: GO:0050232 +name: putrescine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2." [EC:1.4.3.10, MetaCyc:PUTRESCINE-OXIDASE-RXN] +synonym: "putrescine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.10] +xref: EC:1.4.3.10 +xref: MetaCyc:PUTRESCINE-OXIDASE-RXN +xref: RHEA:18273 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0050233 +name: pyranose oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2)." [EC:1.1.3.10, RHEA:10552] +synonym: "glucose 2-oxidase activity" EXACT [EC:1.1.3.10] +synonym: "pyranose-2-oxidase activity" EXACT [EC:1.1.3.10] +synonym: "pyranose:oxygen 2-oxidoreductase activity" EXACT [EC:1.1.3.10] +xref: EC:1.1.3.10 +xref: KEGG_REACTION:R00302 +xref: MetaCyc:PYRANOSE-OXIDASE-RXN +xref: RHEA:10552 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050234 +name: pyrazolylalanine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O." [EC:4.2.1.50, RHEA:24512] +synonym: "beta-pyrazolylalaninase activity" EXACT [EC:4.2.1.50] +synonym: "L-serine hydro-lyase (adding pyrazole)" EXACT [EC:4.2.1.50] +synonym: "L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]" RELATED [EC:4.2.1.50] +xref: EC:4.2.1.50 +xref: KEGG_REACTION:R02378 +xref: MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN +xref: RHEA:24512 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050235 +name: pyridoxal 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH." [EC:1.1.1.107, RHEA:21336] +synonym: "pyridoxal dehydrogenase activity" EXACT [EC:1.1.1.107] +synonym: "pyridoxal:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.107] +xref: EC:1.1.1.107 +xref: KEGG_REACTION:R01707 +xref: MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN +xref: RHEA:21336 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050236 +name: pyridoxine:NADP 4-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal." [EC:1.1.1.65, RHEA:16129] +synonym: "PL reductase activity" EXACT [EC:1.1.1.65] +synonym: "pyridoxal reductase activity" EXACT [EC:1.1.1.65] +synonym: "pyridoxin dehydrogenase activity" EXACT [EC:1.1.1.65] +synonym: "pyridoxine dehydrogenase activity" EXACT [EC:1.1.1.65] +synonym: "pyridoxine:NADP 4-oxidoreductase activity" EXACT [EC:1.1.1.65] +synonym: "pyridoxol dehydrogenase activity" EXACT [EC:1.1.1.65] +xref: EC:1.1.1.65 +xref: KEGG_REACTION:R01708 +xref: MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN +xref: RHEA:16129 +is_a: GO:0004033 ! aldo-keto reductase (NADP) activity + +[Term] +id: GO:0050237 +name: pyridoxine 4-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2." [EC:1.1.3.12, MetaCyc:PYRIDOXINE-4-OXIDASE-RXN] +synonym: "pyridoxin 4-oxidase activity" EXACT [EC:1.1.3.12] +synonym: "pyridoxine:oxygen 4-oxidoreductase activity" EXACT [EC:1.1.3.12] +synonym: "pyridoxol 4-oxidase activity" EXACT [EC:1.1.3.12] +xref: EC:1.1.3.12 +xref: MetaCyc:PYRIDOXINE-4-OXIDASE-RXN +xref: RHEA:15033 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050238 +name: pyridoxine 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor." [EC:1.1.99.9, MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN] +synonym: "pyridoxal-5-dehydrogenase activity" EXACT [EC:1.1.99.9] +synonym: "pyridoxin 5-dehydrogenase activity" EXACT [EC:1.1.99.9] +synonym: "pyridoxine 5'-dehydrogenase activity" EXACT [EC:1.1.99.9] +synonym: "pyridoxine:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.9] +synonym: "pyridoxine:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.9] +synonym: "pyridoxol 5-dehydrogenase activity" EXACT [EC:1.1.99.9] +xref: EC:1.1.99.9 +xref: MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN +xref: RHEA:14497 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0050239 +name: pyrithiamine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3." [EC:3.5.4.20, MetaCyc:PYRITHIAMIN-DEAMINASE-RXN] +synonym: "1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity" EXACT [EC:3.5.4.20] +xref: EC:3.5.4.20 +xref: MetaCyc:PYRITHIAMIN-DEAMINASE-RXN +xref: RHEA:14537 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0050240 +name: pyrogallol 1,2-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+)." [EC:1.13.11.35, RHEA:19673] +synonym: "1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.35] +synonym: "pyrogallol 1,2-dioxygenase activity" EXACT [EC:1.13.11.35] +xref: EC:1.13.11.35 +xref: KEGG_REACTION:R03246 +xref: MetaCyc:PYROGALLOL-12-OXYGENASE-RXN +xref: RHEA:19673 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050241 +name: pyrroline-2-carboxylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+." [EC:1.5.1.1, MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN] +synonym: "delta1-pyrroline-2-carboxylate reductase activity" EXACT [EC:1.5.1.1] +synonym: "L-proline:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.5.1.1] +xref: EC:1.5.1.1 +xref: MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050242 +name: pyruvate, phosphate dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate." [EC:2.7.9.1, RHEA:10756] +synonym: "ATP:pyruvate, phosphate phosphotransferase activity" EXACT [EC:2.7.9.1] +synonym: "orthophosphate dikinase pyruvate" RELATED [EC:2.7.9.1] +synonym: "PPDK" RELATED [EC:2.7.9.1] +synonym: "pyruvate, Pi dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvate,orthophosphate dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvate,phosphate dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvate-inorganic phosphate dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvate-phosphate dikinase (phosphorylating)" EXACT [EC:2.7.9.1] +synonym: "pyruvate-phosphate dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvate-phosphate ligase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvic-phosphate dikinase activity" EXACT [EC:2.7.9.1] +synonym: "pyruvic-phosphate ligase activity" EXACT [EC:2.7.9.1] +xref: EC:2.7.9.1 +xref: KEGG_REACTION:R00206 +xref: MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN +xref: RHEA:10756 +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0050243 +name: pyruvate dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH." [EC:1.2.1.51, RHEA:17425] +synonym: "pyruvate:NADP(+) oxidoreductase activity" EXACT [EC:1.2.1.51] +synonym: "pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.1.51] +synonym: "pyruvate:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.51] +xref: EC:1.2.1.51 +xref: KEGG_REACTION:R00210 +xref: MetaCyc:PYRUVATE-DEHYDROGENASE-NADP%2b-RXN +xref: RHEA:17425 +is_a: GO:0034603 ! pyruvate dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0050244 +name: pyruvate oxidase (CoA-acetylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2)." [EC:1.2.3.6, RHEA:21912] +synonym: "pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.3.6] +xref: EC:1.2.3.6 +xref: KEGG_REACTION:R00211 +xref: MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN +xref: RHEA:21912 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0050245 +name: quercitrinase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin." [EC:3.2.1.66, RHEA:17465] +synonym: "quercitrin 3-L-rhamnohydrolase activity" EXACT [EC:3.2.1.66] +xref: EC:3.2.1.66 +xref: KEGG_REACTION:R02436 +xref: MetaCyc:QUERCITRINASE-RXN +xref: RHEA:17465 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0050246 +name: questin monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+)." [EC:1.14.13.43, RHEA:10836] +synonym: "questin oxygenase activity" EXACT [EC:1.14.13.43] +synonym: "questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)" EXACT [EC:1.14.13.43] +xref: EC:1.14.13.43 +xref: KEGG_REACTION:R02417 +xref: MetaCyc:QUESTIN-MONOOXYGENASE-RXN +xref: RHEA:10836 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050247 +name: raucaffricine beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine." [EC:3.2.1.125, RHEA:14557] +synonym: "raucaffricine b-glucosidase activity" EXACT [] +synonym: "raucaffricine beta-D-glucohydrolase activity" EXACT [EC:3.2.1.125] +synonym: "raucaffricine beta-D-glucosidase activity" EXACT [EC:3.2.1.125] +synonym: "raucaffricine glucosidase activity" EXACT [EC:3.2.1.125] +xref: EC:3.2.1.125 +xref: KEGG_REACTION:R03703 +xref: MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN +xref: RHEA:14557 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0050248 +name: Renilla-luciferin 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light." [EC:1.13.12.5, MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN] +synonym: "aequorin activity" NARROW [EC:1.13.12.5] +synonym: "luciferase (Renilla luciferin)" EXACT [EC:1.13.12.5] +synonym: "luciferase activity" BROAD [EC:1.13.12.5] +synonym: "Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.5] +synonym: "Renilla-type luciferase activity" EXACT [EC:1.13.12.5] +xref: EC:1.13.12.5 +xref: MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN +xref: RHEA:14765 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0050249 +name: Renilla-luciferin sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate." [EC:2.8.2.10, RHEA:20481] +synonym: "3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity" EXACT [EC:2.8.2.10] +synonym: "luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)" EXACT [EC:2.8.2.10] +synonym: "luciferin sulfokinase activity" EXACT [EC:2.8.2.10] +synonym: "luciferin sulfotransferase activity" BROAD [EC:2.8.2.10] +synonym: "Renilla-luciferin sulphotransferase activity" EXACT [] +xref: EC:2.8.2.10 +xref: KEGG_REACTION:R03138 +xref: MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN +xref: RHEA:20481 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050250 +name: retinal oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2." [EC:1.2.3.11, MetaCyc:RETINAL-OXIDASE-RXN] +synonym: "retinal:oxygen oxidoreductase activity" EXACT [EC:1.2.3.11] +synonym: "retinene oxidase activity" RELATED [EC:1.2.3.11] +xref: EC:1.2.3.11 +xref: MetaCyc:RETINAL-OXIDASE-RXN +xref: RHEA:22520 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0050251 +name: retinol isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinol = 11-cis-retinol." [GOC:pde, RHEA:19141] +synonym: "all-trans-retinol 11-cis-trans-isomerase activity" EXACT [] +synonym: "all-trans-retinol isomerase activity" EXACT [] +xref: KEGG_REACTION:R02369 +xref: MetaCyc:RETINOL-ISOMERASE-RXN +xref: Reactome:R-HSA-2465926 "An atROL isomerase isomerises atROL to 11cROL" +xref: RHEA:19141 +is_a: GO:0016859 ! cis-trans isomerase activity + +[Term] +id: GO:0050252 +name: retinol O-fatty-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester." [EC:2.3.1.76, MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN] +synonym: "acyl-CoA:retinol O-acyltransferase activity" EXACT [EC:2.3.1.76] +synonym: "retinol acyltransferase activity" EXACT [EC:2.3.1.76] +synonym: "retinol fatty-acyltransferase activity" EXACT [EC:2.3.1.76] +xref: EC:2.3.1.76 +xref: MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-2465919 "AWAT2 transfers PALM to 11cROL forming 11cRPALM" +xref: Reactome:R-HSA-8848585 "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM" +xref: RHEA:11488 +is_a: GO:0008374 ! O-acyltransferase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0050253 +name: retinyl-palmitate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+." [MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN, RHEA:21508] +synonym: "retinyl ester hydrolase activity" EXACT [EC:3.1.1.21] +synonym: "retinyl palmitate hydrolase activity" EXACT [EC:3.1.1.21] +synonym: "retinyl palmitate hydrolyase activity" EXACT [EC:3.1.1.21] +synonym: "retinyl-palmitate palmitohydrolase activity" EXACT [EC:3.1.1.21] +xref: EC:3.1.1 +xref: KEGG_REACTION:R02368 +xref: MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN +xref: Reactome:R-HSA-2404133 "A REH hydrolses atREs to atROL and FAs" +xref: Reactome:R-HSA-8848355 "PNPLA4 hydrolyzes retinyl palmitate" +xref: Reactome:R-HSA-975593 "PNLIP:CLPS hydrolyses RPALM to atROL and PALM" +xref: Reactome:R-HSA-975594 "PLB1 hydrolyses RPALM to atROL" +xref: RHEA:21508 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0050254 +name: rhodopsin kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin." [EC:2.7.11.14, MetaCyc:RHODOPSIN-KINASE-RXN] +synonym: "ATP:rhodopsin phosphotransferase activity" EXACT [EC:2.7.11.14] +synonym: "cone opsin kinase activity" NARROW [EC:2.7.11.14] +synonym: "G-protein-coupled receptor kinase 1 activity" NARROW [EC:2.7.11.14] +synonym: "GPCR kinase 1 activity" NARROW [EC:2.7.11.14] +synonym: "GRK1" RELATED [EC:2.7.11.14] +synonym: "GRK7" RELATED [EC:2.7.11.14] +synonym: "opsin kinase (phosphorylating) activity" EXACT [EC:2.7.11.14] +synonym: "opsin kinase activity" EXACT [EC:2.7.11.14] +synonym: "rhodopsin kinase (phosphorylating) activity" EXACT [EC:2.7.11.14] +synonym: "RK" RELATED [EC:2.7.11.14] +synonym: "STK14" RELATED [EC:2.7.11.14] +xref: EC:2.7.11.14 +xref: MetaCyc:2.7.11.14-RXN +xref: Reactome:R-HSA-2581474 "GRK1,4,7 phosphorylate MII to p-MII" +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0050255 +name: ribitol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH." [EC:1.1.1.56, RHEA:20053] +synonym: "adonitol dehydrogenase activity" EXACT [EC:1.1.1.56] +synonym: "ribitol dehydrogenase A (wild type)" RELATED [EC:1.1.1.56] +synonym: "ribitol dehydrogenase B (mutant enzyme with different properties)" RELATED [EC:1.1.1.56] +synonym: "ribitol dehydrogenase D (mutant enzyme with different properties)" RELATED [EC:1.1.1.56] +synonym: "ribitol:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.56] +xref: EC:1.1.1.56 +xref: KEGG_REACTION:R01895 +xref: MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN +xref: RHEA:20053 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050256 +name: ribitol-5-phosphate 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+." [EC:1.1.1.137, MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN] +synonym: "D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.137] +synonym: "dehydrogenase, ribitol 5-phosphate" EXACT [EC:1.1.1.137] +xref: EC:1.1.1.137 +xref: MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050257 +name: riboflavin phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN." [EC:2.7.1.42, RHEA:20409] +synonym: "alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.42] +synonym: "D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.42] +synonym: "G-1-P phosphotransferase activity" EXACT [EC:2.7.1.42] +synonym: "riboflavine phosphotransferase activity" EXACT [EC:2.7.1.42] +xref: EC:2.7.1.42 +xref: KEGG_REACTION:R00550 +xref: MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN +xref: RHEA:20409 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050258 +name: riboflavinase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome." [EC:3.5.99.1, RHEA:11408] +synonym: "riboflavin hydrolase activity" EXACT [EC:3.5.99.1] +xref: EC:3.5.99.1 +xref: KEGG_REACTION:R01732 +xref: MetaCyc:RIBOFLAVINASE-RXN +xref: RHEA:11408 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0050259 +name: ribose 1-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH." [EC:1.1.1.115, RHEA:11676] +synonym: "D-ribose dehydrogenase (NADP+)" EXACT [EC:1.1.1.115] +synonym: "D-ribose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.115] +synonym: "NADP-pentose-dehydrogenase activity" EXACT [EC:1.1.1.115] +xref: EC:1.1.1.115 +xref: KEGG_REACTION:R01079 +xref: MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN +xref: RHEA:11676 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050260 +name: ribose-5-phosphate-ammonia ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate." [EC:6.3.4.7, RHEA:13777] +synonym: "5-phosphoribosylamine synthetase activity" EXACT [EC:6.3.4.7] +synonym: "ammonia-ribose 5-phosphate aminotransferase activity" EXACT [EC:6.3.4.7] +synonym: "ribose 5-phosphate aminotransferase activity" EXACT [EC:6.3.4.7] +synonym: "ribose-5-phosphate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.4.7] +xref: EC:6.3.4.7 +xref: KEGG_REACTION:R01053 +xref: MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN +xref: RHEA:13777 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0050261 +name: ribose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: ribofuranose = D-ribulose." [EC:5.3.1.20, RHEA:20796] +synonym: "D-ribose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.20] +synonym: "D-ribose isomerase activity" EXACT [EC:5.3.1.20] +synonym: "D-ribose ketol-isomerase activity" EXACT [EC:5.3.1.20] +xref: EC:5.3.1.20 +xref: KEGG_REACTION:R01081 +xref: MetaCyc:RIBOSE-ISOMERASE-RXN +xref: RHEA:20796 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0050262 +name: ribosylnicotinamide kinase activity +namespace: molecular_function +alt_id: GO:0000816 +def: "Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide." [EC:2.7.1.22, PMID:17914902, RHEA:14017] +synonym: "ATP:N-ribosylnicotinamide 5'-phosphotransferase activity" EXACT [EC:2.7.1.22] +synonym: "nicotinamide riboside kinase activity" EXACT [PMID:15137942] +synonym: "ribosylnicotinamide kinase (phosphorylating)" EXACT [EC:2.7.1.22] +xref: EC:2.7.1.22 +xref: KEGG_REACTION:R02324 +xref: MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN +xref: Reactome:R-HSA-8869627 "NMRK2 phosphorylates NR to yield NMN" +xref: Reactome:R-HSA-8869633 "NMRK1 phosphorylates NR to yield NMN" +xref: RHEA:14017 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050263 +name: ribosylpyrimidine nucleosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine." [EC:3.2.2.8, MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN] +synonym: "N-ribosylpyrimidine nucleosidase activity" EXACT [EC:3.2.2.8] +synonym: "N-ribosylpyrimidine ribohydrolase activity" EXACT [EC:3.2.2.8] +synonym: "nucleoside ribohydrolase activity" BROAD [EC:3.2.2.8] +synonym: "pyrimidine nucleosidase activity" EXACT [EC:3.2.2.8] +synonym: "pyrimidine-nucleoside ribohydrolase activity" EXACT [EC:3.2.2.8] +synonym: "RihB" RELATED [EC:3.2.2.8] +synonym: "YeiK" RELATED [EC:3.2.2.8] +xref: EC:3.2.2.8 +xref: MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0050264 +name: rifamycin-B oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O." [EC:1.10.3.6, RHEA:11292] +synonym: "rifamycin B oxidase activity" EXACT [EC:1.10.3.6] +synonym: "rifamycin-B-oxidase activity" EXACT [] +synonym: "rifamycin-B:oxygen oxidoreductase activity" EXACT [EC:1.10.3.6] +xref: EC:1.10.3.6 +xref: KEGG_REACTION:R03736 +xref: MetaCyc:RIFAMYCIN-B-OXIDASE-RXN +xref: RHEA:11292 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0050265 +name: RNA uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.52, MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN] +synonym: "poly(U) polymerase activity" EXACT [GOC:dph, GOC:mah] +synonym: "polynucleotide uridylyltransferase activity" EXACT [GOC:dph, GOC:mah] +synonym: "terminal uridylyltransferase activity" EXACT [EC:2.7.7.52] +synonym: "TUT activity" EXACT [EC:2.7.7.52] +synonym: "UTP:RNA uridylyltransferase activity" EXACT [] +xref: EC:2.7.7.52 +xref: MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN +xref: Reactome:R-HSA-8941312 "ZCCHC6, ZCCHC11 are mRNA uridyltransferases" +is_a: GO:0070569 ! uridylyltransferase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA + +[Term] +id: GO:0050266 +name: rosmarinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate." [EC:2.3.1.140, MetaCyc:ROSMARINATE-SYNTHASE-RXN] +synonym: "4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity" EXACT [EC:2.3.1.140] +synonym: "caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity" EXACT [EC:2.3.1.140] +synonym: "caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity" EXACT [EC:2.3.1.140] +synonym: "rosmarinic acid synthase activity" EXACT [EC:2.3.1.140] +xref: EC:2.3.1.140 +xref: MetaCyc:ROSMARINATE-SYNTHASE-RXN +xref: RHEA:22344 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050267 +name: rubber cis-polyprenylcistransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit." [EC:2.5.1.20, MetaCyc:RUBBER-CIS-POLYPRENYLCISTRANSFERASE-RXN] +synonym: "cis-prenyl transferase activity" EXACT [EC:2.5.1.20] +synonym: "isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity" EXACT [EC:2.5.1.20] +synonym: "poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity" EXACT [EC:2.5.1.20] +synonym: "rubber allyltransferase activity" EXACT [EC:2.5.1.20] +synonym: "rubber polymerase activity" EXACT [EC:2.5.1.20] +synonym: "rubber prenyltransferase activity" EXACT [EC:2.5.1.20] +synonym: "rubber transferase activity" BROAD [EC:2.5.1.20] +xref: EC:2.5.1.20 +xref: MetaCyc:2.5.1.20-RXN +is_a: GO:0002094 ! polyprenyltransferase activity + +[Term] +id: GO:0050268 +name: coniferyl-alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH." [EC:1.1.1.194, MetaCyc:RXN-1107] +synonym: "coniferyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.194] +xref: EC:1.1.1.194 +xref: MetaCyc:RXN-2602 +xref: RHEA:22444 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050269 +name: coniferyl-aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+." [EC:1.2.1.68, MetaCyc:RXN-1241] +synonym: "coniferyl aldehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.68] +xref: EC:1.2.1.68 +xref: MetaCyc:RXN-1241 +is_a: GO:0004030 ! aldehyde dehydrogenase [NAD(P)+] activity + +[Term] +id: GO:0050270 +name: S-adenosylhomocysteine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+)." [EC:3.5.4.28, RHEA:20716] +synonym: "adenosylhomocysteine deaminase activity" EXACT [EC:3.5.4.28] +synonym: "S-adenosyl-L-homocysteine aminohydrolase activity" EXACT [EC:3.5.4.28] +xref: EC:3.5.4.28 +xref: KEGG_REACTION:R00193 +xref: MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN +xref: RHEA:20716 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0050271 +name: S-alkylcysteine lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate." [EC:4.4.1.6, MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN] +synonym: "alkyl cysteine lyase activity" EXACT [EC:4.4.1.6] +synonym: "alkylcysteine lyase activity" EXACT [EC:4.4.1.6] +synonym: "S-alkyl-L-cysteinase activity" EXACT [EC:4.4.1.6] +synonym: "S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity" EXACT [EC:4.4.1.6] +synonym: "S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.6] +synonym: "S-alkyl-L-cysteine lyase activity" EXACT [EC:4.4.1.6] +synonym: "S-alkyl-L-cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.6] +synonym: "S-alkylcysteinase activity" EXACT [EC:4.4.1.6] +xref: EC:4.4.1.6 +xref: MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN +xref: RHEA:22424 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0050272 +name: S-carboxymethylcysteine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+)." [EC:4.5.1.5, RHEA:22868] +synonym: "3-chloro-L-alanine chloride-lyase (adding thioglycolate)" EXACT [EC:4.5.1.5] +synonym: "3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming)" EXACT [EC:4.5.1.5] +synonym: "S-carboxymethyl-L-cysteine synthase activity" EXACT [EC:4.5.1.5] +xref: EC:4.5.1.5 +xref: KEGG_REACTION:R04003 +xref: MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN +xref: RHEA:22868 +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0050273 +name: S-succinylglutathione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate." [EC:3.1.2.13, RHEA:16713] +xref: EC:3.1.2.13 +xref: KEGG_REACTION:R00499 +xref: MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN +xref: RHEA:16713 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0050274 +name: salicyl-alcohol beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP." [EC:2.4.1.172, RHEA:11512] +synonym: "salicyl-alcohol b-D-glucosyltransferase activity" EXACT [] +synonym: "salicyl-alcohol glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.172] +synonym: "UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity" EXACT [EC:2.4.1.172] +synonym: "UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.172] +synonym: "uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity" EXACT [EC:2.4.1.172] +xref: EC:2.4.1.172 +xref: KEGG_REACTION:R03558 +xref: MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:11512 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050275 +name: scopoletin glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP." [EC:2.4.1.128, RHEA:20453] +synonym: "SGTase activity" EXACT [EC:2.4.1.128] +synonym: "UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.128] +synonym: "UDPglucose:scopoletin glucosyltransferase activity" EXACT [EC:2.4.1.128] +synonym: "UDPglucose:scopoletin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.128] +synonym: "uridine diphosphoglucose-scopoletin glucosyltransferase activity" EXACT [EC:2.4.1.128] +xref: EC:2.4.1.128 +xref: KEGG_REACTION:R03594 +xref: MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:20453 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050276 +name: scyllo-inosamine 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+)." [EC:2.7.1.65, RHEA:18605] +synonym: "ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity" EXACT [EC:2.7.1.65] +synonym: "ATP:inosamine phosphotransferase activity" EXACT [EC:2.7.1.65] +synonym: "scyllo-inosamine kinase (phosphorylating)" EXACT [EC:2.7.1.65] +synonym: "scyllo-inosamine kinase activity" EXACT [] +xref: EC:2.7.1.65 +xref: KEGG_REACTION:R03384 +xref: MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN +xref: RHEA:18605 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050277 +name: sedoheptulokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate." [EC:2.7.1.14, RHEA:23844] +synonym: "ATP:sedoheptulose 7-phosphotransferase activity" EXACT [EC:2.7.1.14] +synonym: "heptulokinase activity" EXACT [EC:2.7.1.14] +synonym: "sedoheptulokinase (phosphorylating)" EXACT [EC:2.7.1.14] +xref: EC:2.7.1.14 +xref: KEGG_REACTION:R01844 +xref: MetaCyc:SEDOHEPTULOKINASE-RXN +xref: Reactome:R-HSA-8959719 "SHPK phosphorylates Sedo to Sedo7P" +xref: RHEA:23844 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050278 +name: sedoheptulose-bisphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate." [EC:3.1.3.37, MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN] +synonym: "SBPase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose 1,7-bisphosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose 1,7-diphosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose 1,7-diphosphate phosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose bisphosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose diphosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose-1,7-bisphosphatase activity" EXACT [EC:3.1.3.37] +synonym: "sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.37] +xref: EC:3.1.3.37 +xref: MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN +xref: RHEA:17461 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050279 +name: sepiapterin deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3." [EC:3.5.4.24, MetaCyc:SEPIAPTERIN-DEAMINASE-RXN] +synonym: "sepiapterin aminohydrolase activity" EXACT [EC:3.5.4.24] +xref: EC:3.5.4.24 +xref: MetaCyc:SEPIAPTERIN-DEAMINASE-RXN +xref: RHEA:14025 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0050280 +name: sequoyitol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH." [EC:1.1.1.143, RHEA:11300] +synonym: "5-O-methyl-myo-inositol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.143] +xref: EC:1.1.1.143 +xref: KEGG_REACTION:R03497 +xref: MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN +xref: RHEA:11300 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050281 +name: serine-glyoxylate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine." [EC:2.6.1.45, MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN] +synonym: "L-serine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.45] +synonym: "serine--glyoxylate aminotransferase activity" EXACT [] +synonym: "SGAT activity" EXACT [EC:2.6.1.45] +xref: EC:2.6.1.45 +xref: MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN +xref: RHEA:19125 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050282 +name: serine 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH." [EC:1.4.1.7, MetaCyc:SERINE-DEHYDROGENASE-RXN] +synonym: "L-serine:NAD oxidoreductase (deaminating) activity" EXACT [EC:1.4.1.7] +synonym: "L-serine:NAD+ 2-oxidoreductase (deaminating)" EXACT [EC:1.4.1.7] +synonym: "serine dehydrogenase activity" EXACT [] +xref: EC:1.4.1.7 +xref: MetaCyc:SERINE-DEHYDROGENASE-RXN +xref: RHEA:20884 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050283 +name: serine-sulfate ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate." [EC:4.3.1.10, MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN] +synonym: "(L-SOS)lyase activity" EXACT [EC:4.3.1.10] +synonym: "L-serine-O-sulfate ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.10] +synonym: "serine-sulphate ammonia-lyase activity" EXACT [] +xref: EC:4.3.1.10 +xref: MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN +xref: RHEA:15605 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0050284 +name: sinapate 1-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose." [EC:2.4.1.120, MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN] +synonym: "UDP-glucose:sinapate D-glucosyltransferase activity" EXACT [EC:2.4.1.120] +synonym: "UDPglucose:sinapate D-glucosyltransferase activity" EXACT [EC:2.4.1.120] +synonym: "UDPglucose:sinapic acid glucosyltransferase activity" EXACT [EC:2.4.1.120] +synonym: "uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity" EXACT [EC:2.4.1.120] +synonym: "uridine diphosphoglucose-sinapate glucosyltransferase activity" EXACT [EC:2.4.1.120] +xref: EC:2.4.1.120 +xref: MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:13305 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050285 +name: sinapine esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate." [EC:3.1.1.49, RHEA:10016] +synonym: "aromatic choline esterase activity" EXACT [EC:3.1.1.49] +synonym: "sinapoylcholine sinapohydrolase activity" EXACT [EC:3.1.1.49] +xref: EC:3.1.1.49 +xref: KEGG_REACTION:R02381 +xref: MetaCyc:SINAPINE-ESTERASE-RXN +xref: RHEA:10016 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050286 +name: sorbitol-6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate." [EC:3.1.3.50, RHEA:24580] +synonym: "sorbitol-6-phosphate phosphatase activity" EXACT [EC:3.1.3.50] +synonym: "sorbitol-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.50] +xref: EC:3.1.3.50 +xref: KEGG_REACTION:R02866 +xref: MetaCyc:SORBITOL-6-PHOSPHATASE-RXN +xref: RHEA:24580 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050287 +name: sorbose 5-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH." [EC:1.1.1.123, RHEA:15001] +synonym: "5-keto-D-fructose reductase activity" EXACT [EC:1.1.1.123] +synonym: "5-ketofructose reductase activity" EXACT [EC:1.1.1.123] +synonym: "L-sorbose:NADP+ 5-oxidoreductase activity" EXACT [EC:1.1.1.123] +synonym: "reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity" EXACT [EC:1.1.1.123] +synonym: "sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.123] +xref: EC:1.1.1.123 +xref: KEGG_REACTION:R01694 +xref: MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN +xref: RHEA:15001 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050288 +name: sorbose dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2)." [EC:1.1.99.12, RHEA:14713] +synonym: "L-sorbose:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.12] +synonym: "L-sorbose:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.12] +xref: EC:1.1.99.12 +xref: KEGG_REACTION:R01696 +xref: MetaCyc:SORBOSE-DEHYDROGENASE-RXN +xref: RHEA:14713 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0050289 +name: spermidine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor." [EC:1.5.99.6, MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN] +synonym: "spermidine:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.6] +synonym: "spermidine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.6] +xref: EC:1.5.99.6 +xref: MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN +xref: RHEA:14273 +is_a: GO:0016645 ! oxidoreductase activity, acting on the CH-NH group of donors + +[Term] +id: GO:0050290 +name: sphingomyelin phosphodiesterase D activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+)." [EC:3.1.4.41, RHEA:20984] +synonym: "sphingomyelin ceramide-phosphohydrolase activity" EXACT [EC:3.1.4.41] +synonym: "sphingomyelinase D" RELATED [EC:3.1.4.41] +xref: EC:3.1.4.41 +xref: KEGG_REACTION:R02542 +xref: MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN +xref: RHEA:20984 +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0050291 +name: sphingosine N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine." [EC:2.3.1.24, MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN, PMID:12069845] +synonym: "acyl-CoA:sphingosine N-acyltransferase activity" EXACT [EC:2.3.1.24] +synonym: "ceramide synthase activity" EXACT [] +synonym: "ceramide synthetase activity" EXACT [EC:2.3.1.24] +synonym: "dihydroceramide synthase activity" EXACT [] +synonym: "sphingosine acyltransferase activity" EXACT [EC:2.3.1.24] +xref: EC:2.3.1.24 +xref: MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN +xref: Reactome:R-HSA-428185 "sphinganine + stearyl-CoA => dihydroceramide + CoASH" +xref: RHEA:23768 +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0050292 +name: steroid 9-alpha-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O." [EC:1.14.99.24, RHEA:19557] +synonym: "steroid 9-alpha-hydroxylase activity" EXACT [EC:1.14.99.24] +synonym: "steroid 9a-monooxygenase activity" EXACT [] +synonym: "steroid 9alpha-hydroxylase activity" EXACT [EC:1.14.99.24] +synonym: "steroid 9alpha-monooxygenase activity" EXACT [EC:1.14.99.24] +synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)" EXACT [EC:1.14.99.24] +xref: EC:1.14.99.24 +xref: KEGG_REACTION:R04392 +xref: MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN +xref: RHEA:19557 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050293 +name: steroid-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate." [EC:3.1.1.37, RHEA:13721] +synonym: "testololactone lactonohydrolase activity" EXACT [EC:3.1.1.37] +xref: EC:3.1.1.37 +xref: KEGG_REACTION:R03641 +xref: MetaCyc:STEROID-LACTONASE-RXN +xref: RHEA:13721 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050294 +name: steroid sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate." [EC:2.8.2.15, MetaCyc:STEROID-SULFOTRANSFERASE-RXN] +subset: goslim_chembl +synonym: "3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity" EXACT [EC:2.8.2.15] +synonym: "steroid alcohol sulfotransferase" BROAD [EC:2.8.2.15] +synonym: "steroid sulphotransferase activity" EXACT [] +xref: EC:2.8.2.15 +xref: MetaCyc:STEROID-SULFOTRANSFERASE-RXN +xref: Reactome:R-HSA-176517 "SULTs transfer (SO4)2- group to PREG" +xref: Reactome:R-HSA-176521 "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP" +xref: Reactome:R-HSA-176631 "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050295 +name: steryl-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol." [EC:3.2.1.104, RHEA:11956] +synonym: "cholesteryl-beta-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.104] +synonym: "steryl-b-glucosidase activity" EXACT [] +xref: EC:3.2.1.104 +xref: KEGG_REACTION:R01460 +xref: MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN +xref: RHEA:11956 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0050296 +name: stipitatonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate." [EC:4.1.1.60, RHEA:13885] +synonym: "stipitatonate carboxy-lyase (decyclizing)" EXACT [EC:4.1.1.60] +synonym: "stipitatonate carboxy-lyase (decyclizing, stipitatate-forming)" EXACT [EC:4.1.1.60] +xref: EC:4.1.1.60 +xref: KEGG_REACTION:R03739 +xref: MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN +xref: RHEA:13885 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050297 +name: stizolobate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde." [EC:1.13.11.29, MetaCyc:STIZOLOBATE-SYNTHASE-RXN] +synonym: "3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)" EXACT [EC:1.13.11.29] +xref: EC:1.13.11.29 +xref: MetaCyc:STIZOLOBATE-SYNTHASE-RXN +xref: RHEA:21220 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050298 +name: stizolobinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde." [EC:1.13.11.30, MetaCyc:STIZOLOBINATE-SYNTHASE-RXN] +synonym: "3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)" EXACT [EC:1.13.11.30] +xref: EC:1.13.11.30 +xref: MetaCyc:STIZOLOBINATE-SYNTHASE-RXN +xref: RHEA:18465 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050299 +name: streptomycin 3''-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate." [EC:2.7.1.87, RHEA:18377] +synonym: "ATP:streptomycin 3''-phosphotransferase activity" EXACT [EC:2.7.1.87] +synonym: "streptomycin 3''-kinase (phosphorylating)" EXACT [EC:2.7.1.87] +synonym: "streptomycin 3''-phosphotransferase activity" EXACT [EC:2.7.1.87] +xref: EC:2.7.1.87 +xref: KEGG_REACTION:R02227 +xref: MetaCyc:STREPTOMYCIN-3-KINASE-RXN +xref: RHEA:18377 +is_a: GO:0034071 ! aminoglycoside phosphotransferase activity + +[Term] +id: GO:0050300 +name: aminoglycoside 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate." [EC:2.7.1.72, RHEA:22268] +synonym: "APH(6) activity" EXACT [EC:2.7.1.72] +synonym: "ATP:streptomycin 6-phosphotransferase activity" NARROW [EC:2.7.1.72] +synonym: "SM 6-kinase activity" NARROW [EC:2.7.1.72] +synonym: "streptidine kinase (phosphorylating)" NARROW [EC:2.7.1.72] +synonym: "streptidine kinase activity" NARROW [EC:2.7.1.72] +synonym: "streptomycin 6-kinase (phosphorylating)" NARROW [EC:2.7.1.72] +synonym: "streptomycin 6-kinase activity" NARROW [] +synonym: "streptomycin 6-O-phosphotransferase activity" NARROW [EC:2.7.1.72] +synonym: "streptomycin 6-phosphotransferase activity" NARROW [EC:2.7.1.72] +xref: EC:2.7.1.72 +xref: KEGG_REACTION:R02225 +xref: MetaCyc:STREPTOMYCIN-6-KINASE-RXN +xref: RHEA:22268 +is_a: GO:0034071 ! aminoglycoside phosphotransferase activity + +[Term] +id: GO:0050301 +name: streptomycin-6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin." [EC:3.1.3.39, RHEA:10688] +synonym: "streptomycin 6-phosphate phosphatase activity" EXACT [EC:3.1.3.39] +synonym: "streptomycin 6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.39] +synonym: "streptomycin-6-P phosphohydrolase activity" EXACT [EC:3.1.3.39] +synonym: "streptomycin-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.39] +xref: EC:3.1.3.39 +xref: KEGG_REACTION:R02228 +xref: MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN +xref: RHEA:10688 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050302 +name: indole-3-acetaldehyde oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+)." [EC:1.2.3.7, RHEA:16277] +synonym: "(indol-3-yl)acetaldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.7] +synonym: "AO1" RELATED [EC:1.2.3.7] +synonym: "IAA oxidase activity" EXACT [EC:1.2.3.7] +synonym: "IAAld oxidase activity" EXACT [EC:1.2.3.7] +synonym: "indole-3-acetaldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.7] +synonym: "indoleacetaldehyde oxidase activity" EXACT [EC:1.2.3.7] +xref: EC:1.2.3.7 +xref: KEGG_REACTION:R02681 +xref: MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN +xref: RHEA:16277 +is_a: GO:0018488 ! aryl-aldehyde oxidase activity + +[Term] +id: GO:0050303 +name: lysine 6-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine." [EC:1.4.1.18, MetaCyc:LYSINE-6-DEHYDROGENASE-RXN, RHEA:25117] +synonym: "L-lysine 6-dehydrogenase activity" EXACT [EC:1.4.1.18] +synonym: "L-lysine epsilon-dehydrogenase activity" EXACT [EC:1.4.1.18] +synonym: "L-lysine:NAD+ 6-oxidoreductase (deaminating)" EXACT [EC:1.4.1.18] +synonym: "LysDH activity" EXACT [EC:1.4.1.18] +xref: EC:1.4.1.18 +xref: MetaCyc:LYSINE-6-DEHYDROGENASE-RXN +xref: MetaCyc:PWY-5314 +xref: RHEA:25125 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050304 +name: nitrous-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide." [EC:1.7.2.4, MetaCyc:RXN-12130] +synonym: "N2O reductase activity" EXACT [EC:1.7.2.4] +synonym: "nitrogen:(acceptor) oxidoreductase (N2O-forming)" EXACT [EC:1.7.2.4] +synonym: "nitrogen:acceptor oxidoreductase (N2O-forming)" EXACT [EC:1.7.2.4] +synonym: "nitrous oxide reductase activity" EXACT [EC:1.7.2.4] +xref: EC:1.7.2.4 +xref: KEGG_REACTION:R02804 +xref: MetaCyc:RXN-12130 +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor + +[Term] +id: GO:0050305 +name: strombine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate." [EC:1.5.1.22, RHEA:14061] +synonym: "N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity" EXACT [EC:1.5.1.22] +synonym: "N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)" EXACT [EC:1.5.1.22] +synonym: "strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity" EXACT [EC:1.5.1.22] +xref: EC:1.5.1.22 +xref: KEGG_REACTION:R00368 +xref: MetaCyc:STROMBINE-DEHYDROGENASE-RXN +xref: RHEA:14061 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050306 +name: sucrose 1F-fructosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose." [EC:2.4.1.99, MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN] +synonym: "SST activity" EXACT [EC:2.4.1.99] +synonym: "sucrose 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose-sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose:sucrose 1'-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose:sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose:sucrose 1F-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] +synonym: "sucrose:sucrose fructosyltransferase activity" EXACT [EC:2.4.1.99] +xref: EC:2.4.1.99 +xref: MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN +xref: RHEA:23312 +is_a: GO:0050738 ! fructosyltransferase activity + +[Term] +id: GO:0050307 +name: sucrose-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate." [EC:3.1.3.24, MetaCyc:SUCROSE-PHOSPHATASE-RXN] +synonym: "sucrose-6F-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.24] +synonym: "sucrose-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.24] +xref: EC:3.1.3.24 +xref: KEGG_REACTION:R00805 +xref: KEGG_REACTION:R06211 +xref: MetaCyc:SUCROSE-PHOSPHATASE-RXN +xref: RHEA:19289 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0050308 +name: sugar-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate." [EC:3.1.3.23, MetaCyc:SUGAR-PHOSPHATASE-RXN] +synonym: "sugar-phosphate phosphatase activity" EXACT [] +synonym: "sugar-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.23] +xref: EC:3.1.3.23 +xref: KEGG_REACTION:R00804 +xref: MetaCyc:SUGAR-PHOSPHATASE-RXN +is_a: GO:0019203 ! carbohydrate phosphatase activity + +[Term] +id: GO:0050309 +name: sugar-terminal-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate." [EC:3.1.3.58, MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN] +synonym: "sugar-omega-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.58] +synonym: "xylitol-5-phosphatase activity" NARROW [EC:3.1.3.58] +xref: EC:3.1.3.58 +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0050310 +name: sulfite dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c." [EC:1.8.2.1, MetaCyc:SULFITE-DEHYDROGENASE-RXN] +synonym: "sulfite cytochrome c reductase activity" EXACT [EC:1.8.2.1] +synonym: "sulfite-cytochrome c oxidoreductase activity" EXACT [EC:1.8.2.1] +synonym: "sulfite:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.8.2.1] +synonym: "sulphite dehydrogenase activity" EXACT [] +xref: EC:1.8.2.1 +xref: MetaCyc:SULFITE-DEHYDROGENASE-RXN +is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor + +[Term] +id: GO:0050311 +name: sulfite reductase (ferredoxin) activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin." [EC:1.8.7.1, MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN] +synonym: "ferredoxin-sulfite reductase activity" EXACT [EC:1.8.7.1] +synonym: "hydrogen-sulfide:ferredoxin oxidoreductase activity" EXACT [EC:1.8.7.1] +synonym: "sulphite reductase (ferredoxin) activity" EXACT [] +xref: EC:1.8.7.1 +xref: MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN +is_a: GO:0016673 ! oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0050312 +name: sulfoacetaldehyde lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite." [EC:4.4.1.12, MetaCyc:SULFOACETALDEHYDE-LYASE-RXN] +comment: Note that EC:4.4.1.12 was deleted from EC as the reaction is performed by sulfoacetaldehyde acetyltransferase (EC:2.3.3.15). +synonym: "sulphoacetaldehyde lyase activity" EXACT [] +xref: EC:4.4.1 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0050313 +name: sulfur dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfur + O2 + H2O = sulfite." [EC:1.13.11.18, MetaCyc:SULFUR-DIOXYGENASE-RXN] +synonym: "S-sulfanylglutathione:oxygen oxidoreductase activity" EXACT [EC:1.13.11.18] +synonym: "sulfur oxygenase activity" EXACT [EC:1.13.11.18] +synonym: "sulfur:oxygen oxidoreductase activity" EXACT [EC:1.13.11.18] +synonym: "sulphur dioxygenase activity" EXACT [] +xref: EC:1.13.11.18 +xref: MetaCyc:FESGSHTHIO-RXN +xref: Reactome:R-HSA-1614605 "Persulfide sulfur is dioxygenated" +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050314 +name: sym-norspermidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+)." [EC:2.5.1.23, RHEA:23244] +synonym: "S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.23] +xref: EC:2.5.1.23 +xref: KEGG_REACTION:R03271 +xref: MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN +xref: RHEA:23244 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050315 +name: synephrine dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium." [EC:4.2.1.88, RHEA:32203] +synonym: "1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)" EXACT [EC:4.2.1.88] +xref: EC:4.2.1.88 +xref: KEGG_REACTION:R03359 +xref: MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN +xref: RHEA:32203 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050316 +name: T2-induced deoxynucleotide kinase activity +namespace: molecular_function +def: "Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP." [EC:2.7.4.12, MetaCyc:T2-INDUCED-DEOXYNUCLEOTIDE-KINASE-RXN] +synonym: "ATP:(d)NMP phosphotransferase activity" EXACT [EC:2.7.4.12] +xref: EC:2.7.4.12 +xref: MetaCyc:GMKALT-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0050317 +name: tagatose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+)." [EC:2.7.1.101, RHEA:15513] +synonym: "ATP:D-tagatose 6-phosphotransferase activity" EXACT [EC:2.7.1.101] +synonym: "D-tagatose 6-phosphate kinase activity" EXACT [EC:2.7.1.101] +synonym: "tagatose 6-phosphate kinase (phosphorylating)" EXACT [EC:2.7.1.101] +xref: EC:2.7.1.101 +xref: KEGG_REACTION:R02927 +xref: MetaCyc:TAGATOSE-KINASE-RXN +xref: RHEA:15513 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050318 +name: tannase activity +namespace: molecular_function +def: "Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+)." [EC:3.1.1.20, RHEA:16365] +synonym: "tannase S" RELATED [EC:3.1.1.20] +synonym: "tannin acetylhydrolase activity" EXACT [EC:3.1.1.20] +synonym: "tannin acylhydrolase activity" EXACT [EC:3.1.1.20] +xref: EC:3.1.1.20 +xref: KEGG_REACTION:R00053 +xref: MetaCyc:TANNASE-RXN +xref: RHEA:16365 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050319 +name: tartrate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2)." [EC:4.1.1.73, RHEA:13317] +synonym: "(R,R)-tartrate carboxy-lyase (D-glycerate-forming)" EXACT [EC:4.1.1.73] +synonym: "(R,R)-tartrate carboxy-lyase activity" EXACT [EC:4.1.1.73] +xref: EC:4.1.1.73 +xref: KEGG_REACTION:R01751 +xref: MetaCyc:TARTRATE-DECARBOXYLASE-RXN +xref: RHEA:13317 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050320 +name: tartrate epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate." [EC:5.1.2.5, RHEA:22212] +synonym: "tartaric racemase activity" EXACT [EC:5.1.2.5] +xref: EC:5.1.2.5 +xref: KEGG_REACTION:R02546 +xref: MetaCyc:TARTRATE-EPIMERASE-RXN +xref: RHEA:22212 +is_a: GO:0016856 ! racemase and epimerase activity, acting on hydroxy acids and derivatives + +[Term] +id: GO:0050321 +name: tau-protein kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein." [EC:2.7.11.26, MetaCyc:TAU-PROTEIN-KINASE-RXN] +synonym: "[Tau protein] kinase activity" EXACT [] +synonym: "ATP:tau-protein O-phosphotransferase activity" BROAD [EC:2.7.11.26] +synonym: "brain protein kinase PK40erk activity" NARROW [EC:2.7.11.26] +synonym: "cdk5/p20" RELATED [EC:2.7.11.26] +synonym: "CDK5/p23" RELATED [EC:2.7.11.26] +synonym: "glycogen synthase kinase-3beta activity" RELATED [] +synonym: "GSK" RELATED [EC:2.7.11.26] +synonym: "protein tau kinase activity" EXACT [EC:2.7.11.26] +synonym: "STK31" RELATED [EC:2.7.11.26] +synonym: "tau kinase activity" EXACT [EC:2.7.11.26] +synonym: "tau protein kinase activity" EXACT [EC:2.7.11.26] +synonym: "tau-protein kinase I activity" NARROW [EC:2.7.11.26] +synonym: "tau-protein kinase II activity" NARROW [EC:2.7.11.26] +synonym: "tau-tubulin kinase activity" NARROW [EC:2.7.11.26] +synonym: "TPK" RELATED [EC:2.7.11.26] +synonym: "TPK I" RELATED [EC:2.7.11.26] +synonym: "TPK II" RELATED [EC:2.7.11.26] +synonym: "TTK" RELATED [EC:2.7.11.26] +xref: EC:2.7.11.26 +xref: MetaCyc:TAU-PROTEIN-KINASE-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0050322 +name: taurine-2-oxoglutarate transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate." [EC:2.6.1.55, MetaCyc:RXN-2301] +synonym: "taurine aminotransferase activity" EXACT [] +synonym: "taurine transaminase activity" EXACT [] +synonym: "taurine--alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.55] +synonym: "taurine--glutamate transaminase activity" EXACT [EC:2.6.1.55] +synonym: "taurine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.55] +xref: EC:2.6.1.55 +xref: MetaCyc:RXN-2301 +xref: RHEA:16353 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0050323 +name: taurine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde." [EC:1.4.99.2, RHEA:18709] +synonym: "taurine:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.2] +synonym: "taurine:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.99.2] +xref: EC:1.4.99.2 +xref: KEGG_REACTION:R07167 +xref: MetaCyc:TAURINE-DEHYDROGENASE-RXN +xref: RHEA:18709 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0050324 +name: taurocyamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+)." [EC:2.7.3.4, RHEA:22516] +synonym: "ATP:taurocyamine N-phosphotransferase activity" EXACT [EC:2.7.3.4] +synonym: "ATP:taurocyamine phosphotransferase activity" EXACT [EC:2.7.3.4] +synonym: "taurocyamine phosphotransferase activity" EXACT [EC:2.7.3.4] +xref: EC:2.7.3.4 +xref: KEGG_REACTION:R03785 +xref: MetaCyc:TAUROCYAMINE-KINASE-RXN +xref: RHEA:22516 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016775 ! phosphotransferase activity, nitrogenous group as acceptor + +[Term] +id: GO:0050325 +name: tauropine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine." [EC:1.5.1.23, RHEA:12580] +synonym: "2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)" EXACT [EC:1.5.1.23] +synonym: "N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)" EXACT [EC:1.5.1.23] +xref: EC:1.5.1.23 +xref: KEGG_REACTION:R01683 +xref: MetaCyc:TAUROPINE-DEHYDROGENASE-RXN +xref: RHEA:12580 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050326 +name: taxifolin 8-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O." [EC:1.14.13.19, MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN] +synonym: "taxifolin hydroxylase activity" EXACT [] +synonym: "taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.13.19] +xref: EC:1.14.13.19 +xref: MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050328 +name: tetrahydroberberine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2." [EC:1.3.3.8, MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN] +synonym: "(S)-tetrahydroberberine:oxygen oxidoreductase activity" EXACT [EC:1.3.3.8] +synonym: "(S)-THB oxidase activity" EXACT [EC:1.3.3.8] +synonym: "THB oxidase activity" EXACT [EC:1.3.3.8] +xref: EC:1.3.3.8 +xref: MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN +xref: RHEA:13489 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0050329 +name: tetrahydroxypteridine cycloisomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate." [EC:5.5.1.3, RHEA:18097] +synonym: "tetrahydroxypteridine lyase (isomerizing)" EXACT [EC:5.5.1.3] +xref: EC:5.5.1.3 +xref: KEGG_REACTION:R04154 +xref: MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN +xref: RHEA:18097 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0050330 +name: theanine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine." [EC:3.5.1.65, RHEA:18013] +synonym: "5-N-ethyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.65] +synonym: "L-theanine amidohydrolase activity" EXACT [EC:3.5.1.65] +synonym: "N5-ethyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.65] +xref: EC:3.5.1.65 +xref: KEGG_REACTION:R02930 +xref: MetaCyc:THEANINE-HYDROLASE-RXN +xref: RHEA:18013 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050331 +name: thiamine-diphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate." [EC:2.7.4.15, MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN] +synonym: "ATP:thiamin-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] +synonym: "ATP:thiamine-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] +synonym: "protein bound thiamin diphosphate:ATP phosphoryltransferase activity" EXACT [EC:2.7.4.15] +synonym: "TDP kinase activity" EXACT [EC:2.7.4.15] +synonym: "thiamin diphosphate kinase activity" EXACT [] +synonym: "thiamin diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] +synonym: "thiamin pyrophosphate kinase activity" EXACT [EC:2.7.4.15] +synonym: "thiamin-diphosphate kinase activity" EXACT [] +synonym: "thiamine diphosphate kinase activity" EXACT [EC:2.7.4.15] +xref: EC:2.7.4.15 +xref: MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN +xref: Reactome:R-HSA-997381 "TDPK phosphorylates ThDP to ThTP" +xref: RHEA:11240 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0050332 +name: thiamine pyridinylase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine." [EC:2.5.1.2, RHEA:17697] +synonym: "pyrimidine transferase activity" EXACT [EC:2.5.1.2] +synonym: "thiamin hydrolase activity" EXACT [EC:2.5.1.2] +synonym: "thiamin pyridinolase activity" EXACT [EC:2.5.1.2] +synonym: "thiamin pyridinylase activity" EXACT [] +synonym: "thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.2] +synonym: "thiaminase I activity" NARROW [EC:2.5.1.2] +synonym: "thiamine hydrolase activity" EXACT [EC:2.5.1.2] +synonym: "thiamine pyridinolase activity" EXACT [EC:2.5.1.2] +synonym: "thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.2] +xref: EC:2.5.1.2 +xref: KEGG_REACTION:R02863 +xref: MetaCyc:THIAMIN-PYRIDINYLASE-RXN +xref: RHEA:17697 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050333 +name: thiamin-triphosphatase activity +namespace: molecular_function +alt_id: GO:0048253 +def: "Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate." [EC:3.6.1.28, RHEA:11744] +synonym: "thiamine-triphosphatase activity" EXACT [] +synonym: "thiamine-triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.28] +synonym: "ThTPase activity" EXACT [EC:3.6.1.28] +xref: EC:3.6.1.28 +xref: KEGG_REACTION:R00618 +xref: MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN +xref: Reactome:R-HSA-965067 "THTPA:Mg2+ hydrolyzes ThTP to TDP" +xref: RHEA:11744 +is_a: GO:0017111 ! nucleoside-triphosphatase activity + +[Term] +id: GO:0050334 +name: thiaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)." [EC:3.5.99.2, RHEA:17509] +synonym: "thiaminase II activity" NARROW [EC:3.5.99.2] +xref: EC:3.5.99.2 +xref: KEGG_REACTION:R02133 +xref: MetaCyc:THIAMINASE-RXN +xref: RHEA:17509 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + +[Term] +id: GO:0050335 +name: thiocyanate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate." [EC:5.99.1.1, RHEA:10004] +synonym: "benzyl-thiocyanate isomerase activity" EXACT [EC:5.99.1.1] +synonym: "isothiocyanate isomerase activity" EXACT [EC:5.99.1.1] +xref: EC:5.99.1.1 +xref: KEGG_REACTION:R04010 +xref: MetaCyc:THIOCYANATE-ISOMERASE-RXN +xref: RHEA:10004 +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0050336 +name: thioethanolamine S-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA." [EC:2.3.1.11, RHEA:23280] +synonym: "acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity" EXACT [EC:2.3.1.11] +synonym: "acetyl-CoA:thioethanolamine S-acetyltransferase activity" EXACT [EC:2.3.1.11] +synonym: "thioethanolamine acetyltransferase activity" EXACT [EC:2.3.1.11] +synonym: "thioltransacetylase B activity" EXACT [EC:2.3.1.11] +xref: EC:2.3.1.11 +xref: KEGG_REACTION:R03668 +xref: MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN +xref: RHEA:23280 +is_a: GO:0016418 ! S-acetyltransferase activity + +[Term] +id: GO:0050337 +name: thiosulfate-thiol sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide." [EC:2.8.1.3, MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN] +synonym: "glutathione-dependent thiosulfate reductase activity" EXACT [EC:2.8.1.3] +synonym: "sulfane reductase activity" EXACT [EC:2.8.1.3] +synonym: "sulfane sulfurtransferase activity" EXACT [EC:2.8.1.3] +synonym: "thiosulfate:thiol sulfurtransferase activity" EXACT [EC:2.8.1.3] +synonym: "thiosulphate-thiol sulphurtransferase activity" EXACT [] +xref: EC:2.8.1.3 +xref: MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN +xref: Reactome:R-HSA-1655879 "Thiosulfate can transfer its sulfur atom to glutathione" +xref: RHEA:14505 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0050338 +name: thiosulfate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c." [EC:1.8.2.2, MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN] +synonym: "tetrathionate synthase activity" EXACT [EC:1.8.2.2] +synonym: "thiosulfate oxidase activity" EXACT [EC:1.8.2.2] +synonym: "thiosulfate-acceptor oxidoreductase activity" EXACT [EC:1.8.2.2] +synonym: "thiosulfate-oxidizing enzyme" RELATED [EC:1.8.2.2] +synonym: "thiosulfate:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.8.2.2] +synonym: "thiosulphate dehydrogenase activity" EXACT [] +xref: EC:1.8.2.2 +xref: MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN +is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor + +[Term] +id: GO:0050339 +name: thymidine-triphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTTP + H2O = dTDP + phosphate." [EC:3.6.1.39, MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN] +synonym: "deoxythymidine-5'-triphosphatase activity" EXACT [EC:3.6.1.39] +synonym: "dTTP nucleotidohydrolase activity" EXACT [EC:3.6.1.39] +synonym: "dTTPase activity" EXACT [EC:3.6.1.39] +synonym: "thymidine triphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.39] +xref: EC:3.6.1.39 +xref: MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN +xref: RHEA:19013 +is_a: GO:0017111 ! nucleoside-triphosphatase activity + +[Term] +id: GO:0050340 +name: thymidylate 5'-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate." [EC:3.1.3.35, MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN] +synonym: "deoxythymidylate 5'-nucleotidase activity" EXACT [EC:3.1.3.35] +synonym: "deoxythymidylate phosphohydrolase activity" EXACT [EC:3.1.3.35] +synonym: "deoxythymidylic 5'-nucleotidase activity" EXACT [EC:3.1.3.35] +synonym: "dTMPase activity" EXACT [EC:3.1.3.35] +synonym: "thymidylate 5' phosphatase activity" EXACT [] +synonym: "thymidylate 5'-nucleotidase activity" EXACT [EC:3.1.3.35] +synonym: "thymidylate 5'-phosphohydrolase activity" EXACT [EC:3.1.3.35] +synonym: "thymidylate nucleotidase activity" EXACT [EC:3.1.3.35] +xref: EC:3.1.3.35 +xref: MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN +xref: RHEA:11080 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050341 +name: thymine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2." [EC:1.14.11.6, MetaCyc:THYMINE-DIOXYGENASE-RXN] +synonym: "5-hydroxy-methyluracil dioxygenase activity" EXACT [EC:1.14.11.6] +synonym: "5-hydroxymethyluracil oxygenase activity" EXACT [EC:1.14.11.6] +synonym: "thymine 7-hydroxylase activity" EXACT [EC:1.14.11.6] +synonym: "thymine,2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.6] +synonym: "thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating)" EXACT [EC:1.14.11.6] +xref: EC:1.14.11.6 +xref: MetaCyc:THYMINE-DIOXYGENASE-RXN +xref: RHEA:10316 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0050342 +name: tocopherol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol." [EC:2.1.1.95, MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN] +synonym: "gamma-tocopherol methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity" EXACT [EC:2.1.1.95] +xref: EC:2.1.1.95 +xref: MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN +xref: RHEA:24012 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0050343 +name: trans-2-enoyl-CoA reductase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH." [EC:1.3.1.44, MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN] +synonym: "acyl-CoA:NAD+ trans-2-oxidoreductase activity" EXACT [EC:1.3.1.44] +xref: EC:1.3.1.44 +xref: MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050344 +name: trans-cinnamate 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+)." [EC:1.14.13.14, RHEA:10956] +synonym: "cinnamate 2-hydroxylase activity" EXACT [EC:1.14.13.14] +synonym: "cinnamate 2-monooxygenase activity" EXACT [EC:1.14.13.14] +synonym: "cinnamic 2-hydroxylase activity" EXACT [EC:1.14.13.14] +synonym: "cinnamic acid 2-hydroxylase activity" EXACT [EC:1.14.13.14] +synonym: "trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.14] +synonym: "trans-cinnamic acid 2-hydroxylase activity" EXACT [] +xref: EC:1.14.13.14 +xref: KEGG_REACTION:R02254 +xref: MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN +xref: RHEA:10956 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050345 +name: trans-epoxysuccinate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate." [EC:3.3.2.4, RHEA:20740] +synonym: "tartrate epoxydase activity" EXACT [EC:3.3.2.4] +synonym: "trans-2,3-epoxysuccinate hydrolase activity" EXACT [EC:3.3.2.4] +synonym: "trans-epoxysuccinate hydratase activity" EXACT [EC:3.3.2.4] +xref: EC:3.3.2.4 +xref: KEGG_REACTION:R02547 +xref: MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN +xref: RHEA:20740 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0050346 +name: trans-L-3-hydroxyproline dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+)." [EC:4.2.1.77, RHEA:10320] +synonym: "trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)" EXACT [EC:4.2.1.77] +synonym: "trans-L-3-hydroxyproline hydro-lyase activity" EXACT [EC:4.2.1.77] +xref: EC:4.2.1.77 +xref: KEGG_REACTION:R04374 +xref: MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN +xref: RHEA:10320 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050347 +name: trans-octaprenyltranstransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate." [RHEA:11324] +comment: This term represents a deleted EC activity and is scheduled for obsoletion. +synonym: "(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity" EXACT [EC:2.5.1.11] +synonym: "all-trans-nonaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.11] +synonym: "nonaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] +synonym: "polyprenylpyrophosphate synthetase activity" EXACT [EC:2.5.1.11] +synonym: "solanesyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] +synonym: "solanesyl-diphosphate synthase activity" EXACT [EC:2.5.1.11] +synonym: "SPP synthase activity" EXACT [EC:2.5.1.11] +synonym: "terpenoidallyltransferase activity" EXACT [EC:2.5.1.11] +synonym: "terpenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] +synonym: "trans-prenyltransferase activity" EXACT [EC:2.5.1.11] +xref: EC:2.5.1.84 +xref: EC:2.5.1.85 +xref: KEGG_REACTION:R07267 +xref: RHEA:11324 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050348 +name: trehalose O-mycolyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose." [EC:2.3.1.122, RHEA:23472] +synonym: "alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity" EXACT [EC:2.3.1.122] +synonym: "alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity" EXACT [EC:2.3.1.122] +xref: EC:2.3.1.122 +xref: KEGG_REACTION:R07248 +xref: MetaCyc:RXN1G-874 +xref: RHEA:23472 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050349 +name: triacetate-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + triacetate lactone = triacetate." [EC:3.1.1.38, RHEA:22260] +synonym: "TAL hydrolase activity" EXACT [EC:3.1.1.38] +synonym: "triacetate lactone hydrolase activity" EXACT [EC:3.1.1.38] +synonym: "triacetic acid lactone hydrolase activity" EXACT [EC:3.1.1.38] +synonym: "triacetic lactone hydrolase activity" EXACT [EC:3.1.1.38] +synonym: "triacetolactone lactonohydrolase activity" EXACT [EC:3.1.1.38] +xref: EC:3.1.1.38 +xref: KEGG_REACTION:R03702 +xref: MetaCyc:TRIACETATE-LACTONASE-RXN +xref: RHEA:22260 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050350 +name: trihydroxystilbene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2." [EC:2.3.1.95, MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN] +synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)" BROAD [EC:2.3.1.95] +synonym: "resveratrol synthase activity" EXACT [EC:2.3.1.95] +synonym: "stilbene synthase activity" BROAD [EC:2.3.1.95] +xref: EC:2.3.1.95 +xref: MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN +xref: RHEA:11936 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050351 +name: trimetaphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate." [EC:3.6.1.2, RHEA:11088] +synonym: "inorganic trimetaphosphatase activity" EXACT [EC:3.6.1.2] +synonym: "trimetaphosphate hydrolase activity" EXACT [EC:3.6.1.2] +xref: EC:3.6.1.2 +xref: KEGG_REACTION:R02504 +xref: MetaCyc:TRIMETAPHOSPHATASE-RXN +xref: RHEA:11088 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0050352 +name: trimethylamine-oxide aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde." [EC:4.1.2.32, RHEA:20217] +synonym: "trimethylamine N-oxide aldolase activity" EXACT [EC:4.1.2.32] +synonym: "trimethylamine N-oxide demethylase activity" EXACT [EC:4.1.2.32] +synonym: "trimethylamine N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.32] +synonym: "trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)" EXACT [EC:4.1.2.32] +synonym: "trimethylamine-N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.32] +xref: EC:4.1.2.32 +xref: KEGG_REACTION:R02512 +xref: MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN +xref: RHEA:20217 +xref: UM-BBD_reactionID:r1409 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050353 +name: trimethyllysine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate." [EC:1.14.11.8, RHEA:14181] +synonym: "6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.8] +synonym: "epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] +synonym: "N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.8] +synonym: "TML dioxygenase activity" EXACT [EC:1.14.11.8] +synonym: "TML hydroxylase activity" EXACT [EC:1.14.11.8] +synonym: "TML-alpha-ketoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] +synonym: "TMLD activity" EXACT [EC:1.14.11.8] +synonym: "trimethyllysine alpha-ketoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] +synonym: "trimethyllysine,2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] +xref: EC:1.14.11.8 +xref: KEGG_REACTION:R03451 +xref: MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN +xref: Reactome:R-HSA-71241 "TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA" +xref: RHEA:14181 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0050354 +name: triokinase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+)." [EC:2.7.1.28, RHEA:13941] +synonym: "ATP:D-glyceraldehyde 3-phosphotransferase activity" EXACT [EC:2.7.1.28] +synonym: "D-triokinase activity" EXACT [EC:2.7.1.28] +synonym: "trio triose kinase (phosphorylating)" EXACT [EC:2.7.1.28] +synonym: "triose kinase activity" EXACT [EC:2.7.1.28] +xref: EC:2.7.1.28 +xref: KEGG_REACTION:R01059 +xref: MetaCyc:TRIOKINASE-RXN +xref: Reactome:R-HSA-70349 "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate" +xref: RHEA:13941 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050355 +name: triphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate." [EC:3.6.1.25, RHEA:14157] +synonym: "inorganic triphosphatase activity" EXACT [EC:3.6.1.25] +synonym: "triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.25] +synonym: "tripolyphosphatase activity" EXACT [PMID:24004165] +xref: EC:3.6.1.25 +xref: KEGG_REACTION:R00138 +xref: MetaCyc:TRIPHOSPHATASE-RXN +xref: RHEA:14157 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0050356 +name: tropine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone." [EC:1.1.1.206, RHEA:18357] +synonym: "tropine:NADP+ 3alpha-oxidoreductase activity" EXACT [EC:1.1.1.206] +xref: EC:1.1.1.206 +xref: KEGG_REACTION:R02832 +xref: MetaCyc:TROPINE-DEHYDROGENASE-RXN +xref: RHEA:18357 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050357 +name: tropinesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine." [EC:3.1.1.10, RHEA:23304] +synonym: "atropinase activity" EXACT [EC:3.1.1.10] +synonym: "atropine acylhydrolase activity" EXACT [EC:3.1.1.10] +synonym: "atropine esterase activity" EXACT [EC:3.1.1.10] +synonym: "atropinesterase activity" EXACT [EC:3.1.1.10] +synonym: "tropine esterase activity" EXACT [EC:3.1.1.10] +xref: EC:3.1.1.10 +xref: KEGG_REACTION:R03563 +xref: MetaCyc:TROPINESTERASE-RXN +xref: RHEA:23304 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050358 +name: tropinone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone." [EC:1.1.1.236, RHEA:24244] +synonym: "pseudotropine forming tropinone reductase activity" EXACT [EC:1.1.1.236] +synonym: "pseudotropine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.236] +synonym: "tropinone (psi-tropine-forming) reductase activity" EXACT [EC:1.1.1.236] +synonym: "tropinone reductase II activity" RELATED [EC:1.1.1.236] +xref: EC:1.1.1.236 +xref: KEGG_REACTION:R06734 +xref: MetaCyc:TROPINONE-REDUCTASE-RXN +xref: RHEA:24244 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050359 +name: tropomyosin kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin." [EC:2.7.11.28, MetaCyc:TROPOMYOSIN-KINASE-RXN] +synonym: "ATP:tropomyosin O-phosphotransferase activity" EXACT [EC:2.7.11.28] +synonym: "STK" RELATED [EC:2.7.11.28] +synonym: "tropomyosin kinase (phosphorylating) activity" EXACT [EC:2.7.11.28] +xref: EC:2.7.11.28 +xref: MetaCyc:TROPOMYOSIN-KINASE-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0050360 +name: tryptophan 2'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3." [EC:1.13.99.3, MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN] +synonym: "indole-3-alkane alpha-hydroxylase activity" EXACT [EC:1.13.99.3] +synonym: "indolyl-3-alkan alpha-hydroxylase activity" EXACT [EC:1.13.99.3] +synonym: "L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)" EXACT [EC:1.13.99.3] +synonym: "tryptophan side chain oxidase activity" EXACT [EC:1.13.99.3] +synonym: "tryptophan side chain oxidase II" RELATED [EC:1.13.99.3] +synonym: "tryptophan side chain oxidase type I" RELATED [EC:1.13.99.3] +synonym: "tryptophan side-chain alpha,beta-oxidase activity" RELATED [EC:1.13.99.3] +synonym: "tryptophan side-chain oxidase activity" RELATED [EC:1.13.99.3] +synonym: "TSO activity" RELATED [EC:1.13.99.3] +synonym: "TSO I" RELATED [EC:1.13.99.3] +synonym: "TSO II" RELATED [EC:1.13.99.3] +xref: EC:1.13.99.3 +xref: MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN +xref: RHEA:22620 +is_a: GO:0016701 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + +[Term] +id: GO:0050361 +name: tryptophan 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide." [EC:1.13.12.3, RHEA:16165] +synonym: "L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.3] +xref: EC:1.13.12.3 +xref: KEGG_REACTION:R00679 +xref: MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN +xref: RHEA:16165 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0050362 +name: L-tryptophan:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate." [EC:2.6.1.27, MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN] +synonym: "5-hydroxytryptophan-ketoglutaric transaminase activity" RELATED [EC:2.6.1.27] +synonym: "hydroxytryptophan aminotransferase activity" RELATED [EC:2.6.1.27] +synonym: "L-phenylalanine-2-oxoglutarate aminotransferase activity" RELATED [EC:2.6.1.27] +synonym: "L-tryptophan aminotransferase activity" BROAD [EC:2.6.1.27] +synonym: "L-tryptophan transaminase activity" BROAD [EC:2.6.1.27] +synonym: "tryptophan aminotransferase activity" EXACT [] +synonym: "tryptophan transaminase activity" BROAD [EC:2.6.1.27] +xref: EC:2.6.1.27 +xref: MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN +xref: RHEA:14093 +is_a: GO:0070529 ! L-tryptophan aminotransferase activity + +[Term] +id: GO:0050363 +name: tryptophan dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+." [EC:1.4.1.19, MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN] +synonym: "L-Trp-dehydrogenase activity" EXACT [EC:1.4.1.19] +synonym: "L-tryptophan dehydrogenase activity" EXACT [EC:1.4.1.19] +synonym: "L-tryptophan:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.19] +synonym: "NAD(P)+-L-tryptophan dehydrogenase activity" EXACT [EC:1.4.1.19] +synonym: "TDH" RELATED [EC:1.4.1.19] +synonym: "TrpDH activity" EXACT [EC:1.4.1.19] +xref: EC:1.4.1.19 +xref: MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050364 +name: tryptophan dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan." [EC:2.5.1.34, MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN] +synonym: "4-(gamma,gamma-dimethylallyl)tryptophan synthase activity" EXACT [EC:2.5.1.34] +synonym: "dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity" EXACT [EC:2.5.1.34] +synonym: "dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity" EXACT [EC:2.5.1.34] +synonym: "dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity" EXACT [EC:2.5.1.34] +synonym: "dimethylallyltryptophan synthetase activity" EXACT [EC:2.5.1.34] +synonym: "DMAT synthetase activity" EXACT [EC:2.5.1.34] +xref: EC:2.5.1.34 +xref: MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN +xref: RHEA:14173 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050365 +name: tryptophanamidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+)." [EC:3.5.1.57, RHEA:11012] +synonym: "L-tryptophan aminopeptidase" BROAD [EC:3.5.1.57] +synonym: "L-tryptophanamide amidohydrolase activity" EXACT [EC:3.5.1.57] +synonym: "tryptophan aminopeptidase" BROAD [EC:3.5.1.57] +xref: EC:3.5.1.57 +xref: KEGG_REACTION:R00682 +xref: MetaCyc:TRYPTOPHANAMIDASE-RXN +xref: RHEA:11012 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050366 +name: tyramine N-feruloyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine." [EC:2.3.1.110, MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN] +synonym: "feruloyl-CoA tyramine N-feruloyl-CoA transferase activity" EXACT [EC:2.3.1.110] +synonym: "feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.110] +synonym: "feruloyltyramine synthase activity" EXACT [EC:2.3.1.110] +synonym: "tyramine feruloyltransferase activity" EXACT [EC:2.3.1.110] +synonym: "tyramine N-feruloyl-CoA transferase activity" EXACT [EC:2.3.1.110] +xref: EC:2.3.1.110 +xref: MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN +xref: RHEA:19685 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050367 +name: tyrosine-arginine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+)." [EC:6.3.2.24, RHEA:15345] +synonym: "kyotorphin synthase activity" EXACT [EC:6.3.2.24] +synonym: "kyotorphin synthetase activity" EXACT [EC:6.3.2.24] +synonym: "kyotorphin-synthesizing enzyme activity" EXACT [EC:6.3.2.24] +synonym: "L-tyrosine:L-arginine ligase (AMP-forming)" EXACT [EC:6.3.2.24] +synonym: "tyrosyl-arginine synthase activity" EXACT [EC:6.3.2.24] +xref: EC:6.3.2.24 +xref: KEGG_REACTION:R00735 +xref: MetaCyc:TYROSINE--ARGININE-LIGASE-RXN +xref: RHEA:15345 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0050368 +name: tyrosine 2,3-aminomutase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate." [EC:5.4.3.6, RHEA:15781] +synonym: "L-tyrosine 2,3-aminomutase activity" EXACT [EC:5.4.3.6] +synonym: "tyrosine alpha,beta-mutase activity" EXACT [EC:5.4.3.6] +xref: EC:5.4.3.6 +xref: KEGG_REACTION:R00739 +xref: MetaCyc:TYROSINE-23-AMINOMUTASE-RXN +xref: RHEA:15781 +is_a: GO:0016869 ! intramolecular transferase activity, transferring amino groups + +[Term] +id: GO:0050369 +name: [tyrosine 3-monooxygenase] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]." [EC:2.7.11.6, MetaCyc:TYROSINE-3-MONOOXYGENASE-KINASE-RXN] +synonym: "ATP:tyrosine-3-monoxygenase phosphotransferase activity" EXACT [EC:2.7.11.6] +synonym: "pheochromocytoma tyrosine hydroxylase-associated kinase activity" EXACT [EC:2.7.11.6] +synonym: "STK4" RELATED [EC:2.7.11.6] +synonym: "tyrosine 3-monooxygenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.6] +synonym: "tyrosine 3-monooxygenase kinase activity" EXACT [] +xref: EC:2.7.11.6 +xref: MetaCyc:2.7.11.6-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0050370 +name: tyrosine N-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O." [MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN] +synonym: "CYP79A1 activity" NARROW [] +synonym: "L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)" EXACT [] +synonym: "tyrosine N-hydroxylase activity" EXACT [] +xref: MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050371 +name: tyrosine phenol-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate." [EC:4.1.99.2, RHEA:21704] +synonym: "beta-tyrosinase activity" EXACT [EC:4.1.99.2] +synonym: "L-tyrosine phenol-lyase (deaminating)" EXACT [EC:4.1.99.2] +synonym: "L-tyrosine phenol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.1.99.2] +xref: EC:4.1.99.2 +xref: KEGG_REACTION:R00728 +xref: MetaCyc:TYROSINE-PHENOL-LYASE-RXN +xref: RHEA:21704 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0050372 +name: ubiquitin-calmodulin ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin." [MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN] +synonym: "calmodulin:ubiquitin ligase (AMP-forming)" EXACT [EC:6.3.2.21] +synonym: "ubiquitin-calmodulin synthetase activity" EXACT [EC:6.3.2.21] +synonym: "ubiquityl-calmodulin synthase activity" EXACT [EC:6.3.2.21] +synonym: "ubiquityl-calmodulin synthetase activity" EXACT [EC:6.3.2.21] +synonym: "uCaM-synthetase activity" EXACT [EC:6.3.2.21] +xref: MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN +is_a: GO:0004842 ! ubiquitin-protein transferase activity + +[Term] +id: GO:0050373 +name: UDP-arabinose 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose." [EC:5.1.3.5, RHEA:11320] +synonym: "UDP arabinose epimerase activity" EXACT [EC:5.1.3.5] +synonym: "UDP-D-xylose 4-epimerase activity" EXACT [EC:5.1.3.5] +synonym: "UDP-D-xylose-4-epimerase activity" EXACT [] +synonym: "UDP-L-arabinose 4-epimerase activity" EXACT [EC:5.1.3.5] +synonym: "UDParabinose 4-epimerase activity" EXACT [EC:5.1.3.5] +synonym: "uridine 5'-diphosphate-D-xylose 4-epimerase activity" EXACT [EC:5.1.3.5] +synonym: "uridine diphosphoarabinose epimerase activity" EXACT [EC:5.1.3.5] +xref: EC:5.1.3.5 +xref: KEGG_REACTION:R01473 +xref: MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN +xref: RHEA:11320 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050374 +name: UDP-galacturonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose." [EC:4.1.1.67, RHEA:19725] +synonym: "UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming)" EXACT [EC:4.1.1.67] +synonym: "UDP-D-galacturonate carboxy-lyase activity" EXACT [EC:4.1.1.67] +synonym: "UDP-galacturonic acid decarboxylase activity" EXACT [EC:4.1.1.67] +synonym: "UDPgalacturonate decarboxylase activity" EXACT [EC:4.1.1.67] +synonym: "UDPGalUA carboxy lyase activity" EXACT [EC:4.1.1.67] +xref: EC:4.1.1.67 +xref: KEGG_REACTION:R02636 +xref: MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN +xref: RHEA:19725 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050376 +name: UDP-glucosamine 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine." [EC:5.1.3.16, MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN] +synonym: "UDP-glucosamine epimerase activity" EXACT [] +synonym: "UDPglucosamine 4-epimerase activity" EXACT [EC:5.1.3.16] +xref: EC:5.1.3.16 +xref: MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN +xref: RHEA:23492 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050377 +name: UDP-glucose 4,6-dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose." [EC:4.2.1.76, RHEA:21500] +synonym: "UDP-D-glucose oxidoreductase activity" EXACT [EC:4.2.1.76] +synonym: "UDP-D-glucose-4,6-hydrolyase activity" EXACT [EC:4.2.1.76] +synonym: "UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.76] +synonym: "UDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.76] +synonym: "UDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.76] +synonym: "UDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.76] +xref: EC:4.2.1.76 +xref: KEGG_REACTION:R00293 +xref: MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN +xref: RHEA:21500 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050378 +name: UDP-glucuronate 4-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate." [EC:5.1.3.6, RHEA:11404] +synonym: "UDP glucuronic epimerase activity" EXACT [EC:5.1.3.6] +synonym: "UDP-D-galacturonic acid 4-epimerase activity" EXACT [EC:5.1.3.6] +synonym: "UDP-galacturonate 4-epimerase activity" EXACT [EC:5.1.3.6] +synonym: "UDPglucuronate 4-epimerase activity" EXACT [EC:5.1.3.6] +synonym: "uridine diphospho-D-galacturonic acid" RELATED [EC:5.1.3.6] +synonym: "uridine diphosphoglucuronate epimerase activity" EXACT [EC:5.1.3.6] +synonym: "uridine diphosphoglucuronic epimerase activity" EXACT [EC:5.1.3.6] +xref: EC:5.1.3.6 +xref: KEGG_REACTION:R01385 +xref: MetaCyc:PWY-4861 +xref: MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN +xref: RHEA:11404 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050379 +name: UDP-glucuronate 5'-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate." [EC:5.1.3.12, RHEA:14677] +synonym: "C-5-uronosyl epimerase activity" EXACT [EC:5.1.3.12] +synonym: "UDP-glucuronate 5' epimerase activity" EXACT [] +synonym: "UDP-glucuronic acid 5'-epimerase activity" EXACT [EC:5.1.3.12] +synonym: "UDP-glucuronic acid epimerase activity" EXACT [EC:5.1.3.12] +synonym: "UDPglucuronate 5'-epimerase activity" EXACT [EC:5.1.3.12] +synonym: "uridine diphosphoglucuronate 5'-epimerase activity" EXACT [EC:5.1.3.12] +xref: EC:5.1.3.12 +xref: KEGG_REACTION:R01387 +xref: MetaCyc:UDP-GLUCURONATE-5-EPIMERASE-RXN +xref: Reactome:R-HSA-2024100 "GLCE epimerises GlcA to IdoA" +xref: Reactome:R-HSA-2076371 "GLCE epimerises more GlcA to IdoA as sulfate content rises" +xref: RHEA:14677 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050380 +name: undecaprenyl-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-undecaprenyl diphosphate + H(2)O = all-trans-undecaprenyl phosphate + H(+) + phosphate." [EC:3.6.1.27, RHEA:17069] +synonym: "C(55)-isoprenyl diphosphatase activity" EXACT [EC:3.6.1.27] +synonym: "C(55)-isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] +synonym: "C55-isoprenyl diphosphatase activity" EXACT [EC:3.6.1.27] +synonym: "C55-isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] +synonym: "isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] +synonym: "undecaprenyl-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.27] +xref: EC:3.6.1.27 +xref: KEGG_REACTION:R05627 +xref: MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN +xref: RHEA:17069 +is_a: GO:0016462 ! pyrophosphatase activity + +[Term] +id: GO:0050382 +name: uracil-5-carboxylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil." [EC:4.1.1.66, RHEA:17685] +synonym: "uracil-5-carboxylate carboxy-lyase (uracil-forming)" EXACT [EC:4.1.1.66] +synonym: "uracil-5-carboxylate carboxy-lyase activity" EXACT [EC:4.1.1.66] +synonym: "uracil-5-carboxylic acid decarboxylase activity" EXACT [EC:4.1.1.66] +xref: EC:4.1.1.66 +xref: KEGG_REACTION:R00973 +xref: MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN +xref: RHEA:17685 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050383 +name: uracil dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor." [EC:1.17.99.4, MetaCyc:URACIL-DEHYDROGENASE-RXN] +xref: EC:1.17.99.4 +xref: MetaCyc:URACIL-DEHYDROGENASE-RXN +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0050384 +name: urate-ribonucleotide phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate." [EC:2.4.2.16, RHEA:13909] +synonym: "UAR phosphorylase activity" EXACT [EC:2.4.2.16] +synonym: "urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.16] +synonym: "urate-ribonucleotide:phosphate D-ribosyltransferase activity" EXACT [EC:2.4.2.16] +xref: EC:2.4.2.16 +xref: KEGG_REACTION:R02646 +xref: MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN +xref: RHEA:13909 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0050385 +name: ureidoglycolate lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea." [EC:4.3.2.3, RHEA:11304] +comment: Take care to annotate to the reaction, not simply by enzyme name. Note that the name "ureidoglycolate hydrolase" (listed as a synonym here) has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19 ; GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3 ; GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name. +synonym: "(S)-ureidoglycolate urea-lyase (glyoxylate-forming)" EXACT [EC:4.3.2.3] +synonym: "(S)-ureidoglycolate urea-lyase activity" EXACT [EC:4.3.2.3] +synonym: "ureidoglycolase activity" RELATED [EC:4.3.2.3] +synonym: "ureidoglycolatase activity" RELATED [EC:4.3.2.3] +synonym: "ureidoglycolate hydrolase activity" RELATED [PMID:24107613] +xref: EC:4.3.2.3 +xref: KEGG_REACTION:R00776 +xref: MetaCyc:UREIDOGLYCOLATE-LYASE-RXN +xref: RHEA:11304 +is_a: GO:0016842 ! amidine-lyase activity + +[Term] +id: GO:0050386 +name: ureidosuccinase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+)." [EC:3.5.1.7, RHEA:14365] +synonym: "N-carbamoyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.7] +xref: EC:3.5.1.7 +xref: KEGG_REACTION:R00484 +xref: MetaCyc:UREIDOSUCCINASE-RXN +xref: RHEA:14365 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050387 +name: urethanase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+)." [EC:3.5.1.75, RHEA:21372] +synonym: "urethane amidohydrolase (decarboxylating)" EXACT [EC:3.5.1.75] +synonym: "urethane hydrolase activity" EXACT [EC:3.5.1.75] +xref: EC:3.5.1.75 +xref: KEGG_REACTION:R02359 +xref: MetaCyc:URETHANASE-RXN +xref: RHEA:21372 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050388 +name: uronate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH." [EC:1.1.1.203, RHEA:22404] +synonym: "uronate: NAD-oxidoreductase activity" EXACT [EC:1.1.1.203] +synonym: "uronate:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.203] +synonym: "uronic acid dehydrogenase activity" EXACT [EC:1.1.1.203] +xref: EC:1.1.1.203 +xref: KEGG_REACTION:R01981 +xref: MetaCyc:URONATE-DEHYDROGENASE-RXN +xref: RHEA:22404 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050389 +name: uronolactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate." [EC:3.1.1.19, MetaCyc:URONOLACTONASE-RXN] +synonym: "D-glucurono-6,2-lactone lactonohydrolase activity" EXACT [EC:3.1.1.19] +synonym: "glucuronolactonase activity" EXACT [EC:3.1.1.19] +xref: EC:3.1.1.19 +xref: MetaCyc:URONOLACTONASE-RXN +xref: RHEA:13337 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050390 +name: valine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2)." [EC:4.1.1.14, RHEA:18989] +synonym: "L-valine carboxy-lyase (2-methylpropanamine-forming)" EXACT [EC:4.1.1.14] +synonym: "L-valine carboxy-lyase activity" EXACT [EC:4.1.1.14] +synonym: "leucine decarboxylase activity" EXACT [EC:4.1.1.14] +xref: EC:4.1.1.14 +xref: KEGG_REACTION:R01437 +xref: MetaCyc:VALINE-DECARBOXYLASE-RXN +xref: RHEA:18989 +xref: UM-BBD_reactionID:r1052 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050391 +name: valine dehydrogenase (NADP) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH." [EC:1.4.1.8, MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN] +synonym: "L-valine:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.8] +synonym: "valine dehydrogenase (NADP+) activity" EXACT [] +synonym: "valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)" EXACT [EC:1.4.1.8] +xref: EC:1.4.1.8 +xref: MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN +xref: RHEA:11156 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050392 +name: vicianin beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose." [EC:3.2.1.119, RHEA:14041] +synonym: "(R)-vicianin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.119] +synonym: "vicianin b-glucosidase activity" EXACT [] +synonym: "vicianin hydrolase activity" EXACT [EC:3.2.1.119] +xref: EC:3.2.1.119 +xref: KEGG_REACTION:R03642 +xref: MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN +xref: RHEA:14041 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0050393 +name: vinylacetyl-CoA delta-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA." [EC:5.3.3.3, RHEA:10572] +synonym: "delta3-cis-delta2-trans-enoyl-CoA isomerase" BROAD [EC:5.3.3.3] +synonym: "vinylacetyl coenzyme A delta-isomerase activity" EXACT [EC:5.3.3.3] +synonym: "vinylacetyl coenzyme A isomerase activity" EXACT [EC:5.3.3.3] +synonym: "vinylacetyl-CoA D-isomerase activity" EXACT [] +synonym: "vinylacetyl-CoA delta3-delta2-isomerase activity" EXACT [EC:5.3.3.3] +xref: EC:5.3.3.3 +xref: KEGG_REACTION:R03031 +xref: MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN +xref: RHEA:10572 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0050394 +name: viomycin kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin." [EC:2.7.1.103, MetaCyc:VIOMYCIN-KINASE-RXN] +synonym: "ATP:viomycin O-phosphotransferase activity" EXACT [EC:2.7.1.103] +synonym: "capreomycin phosphotransferase activity" EXACT [EC:2.7.1.103] +synonym: "viomycin phosphotransferase activity" EXACT [EC:2.7.1.103] +xref: EC:2.7.1.103 +xref: MetaCyc:VIOMYCIN-KINASE-RXN +xref: RHEA:20509 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050395 +name: vitexin beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside." [EC:2.4.1.105, RHEA:21956] +synonym: "UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.105] +synonym: "UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.105] +synonym: "uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity" EXACT [EC:2.4.1.105] +synonym: "vitexin b-glucosyltransferase activity" EXACT [] +xref: EC:2.4.1.105 +xref: KEGG_REACTION:R03565 +xref: MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:21956 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050396 +name: vomifoliol 4'-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH." [EC:1.1.1.221, RHEA:22804] +synonym: "vomifoliol:NAD+ 4'-oxidoreductase activity" EXACT [EC:1.1.1.221] +xref: EC:1.1.1.221 +xref: KEGG_REACTION:R04412 +xref: MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN +xref: RHEA:22804 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050397 +name: Watasenia-luciferin 2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light." [EC:1.13.12.8, MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN] +synonym: "luciferase activity" BROAD [EC:1.13.12.8] +synonym: "Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.8] +synonym: "Watasenia-type luciferase activity" EXACT [EC:1.13.12.8] +xref: EC:1.13.12.8 +xref: MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN +xref: RHEA:18057 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +is_a: GO:0045289 ! luciferin monooxygenase activity + +[Term] +id: GO:0050398 +name: wax-ester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate." [EC:3.1.1.50, MetaCyc:WAX-ESTER-HYDROLASE-RXN] +synonym: "jojoba wax esterase" NARROW [EC:3.1.1.50] +synonym: "wax-ester acylhydrolase activity" EXACT [EC:3.1.1.50] +synonym: "WEH" RELATED [EC:3.1.1.50] +xref: EC:3.1.1.50 +xref: MetaCyc:WAX-ESTER-HYDROLASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050399 +name: xanthommatin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin." [EC:1.3.1.41, RHEA:13417] +synonym: "5,12-dihydroxanthommatin:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.41] +xref: EC:1.3.1.41 +xref: KEGG_REACTION:R03787 +xref: MetaCyc:XANTHOMMATIN-REDUCTASE-RXN +xref: RHEA:13417 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050400 +name: xylitol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate." [EC:2.7.1.122, RHEA:20209] +synonym: "ATP:xylitol 5-phosphotransferase activity" EXACT [EC:2.7.1.122] +synonym: "xylitol phosphotransferase activity" EXACT [EC:2.7.1.122] +xref: EC:2.7.1.122 +xref: KEGG_REACTION:R02136 +xref: MetaCyc:XYLITOL-KINASE-RXN +xref: RHEA:20209 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050401 +name: xylonate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O." [EC:4.2.1.82, RHEA:19157] +synonym: "D-xylo-aldonate dehydratase activity" EXACT [EC:4.2.1.82] +synonym: "D-xylonate dehydratase activity" EXACT [EC:4.2.1.82] +synonym: "D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)" EXACT [EC:4.2.1.82] +synonym: "D-xylonate hydro-lyase activity" EXACT [EC:4.2.1.82] +xref: EC:4.2.1.82 +xref: KEGG_REACTION:R02429 +xref: MetaCyc:XYLONATE-DEHYDRATASE-RXN +xref: RHEA:19157 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050402 +name: xylono-1,4-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate." [EC:3.1.1.68, MetaCyc:XYLONO-14-LACTONASE-RXN] +synonym: "D-xylono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.68] +synonym: "xylono-g-lactonase activity" EXACT [EC:3.1.1.68] +synonym: "xylonolactonase activity" EXACT [EC:3.1.1.68] +xref: EC:3.1.1.68 +xref: MetaCyc:XYLONO-14-LACTONASE-RXN +xref: RHEA:18341 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050403 +name: trans-zeatin O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP." [EC:2.4.1.203, RHEA:23224] +synonym: "UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] +synonym: "UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] +synonym: "uridine diphosphoglucose-zeatin O-glucosyltransferase activity" EXACT [EC:2.4.1.203] +synonym: "zeatin O-b-D-glucosyltransferase activity" EXACT [] +synonym: "zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] +synonym: "zeatin O-glucosyltransferase activity" EXACT [EC:2.4.1.203] +xref: EC:2.4.1.203 +xref: KEGG_REACTION:R02118 +xref: MetaCyc:RXN-4723 +xref: RHEA:23224 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050404 +name: zeatin O-beta-D-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP." [EC:2.4.2.40, RHEA:14721] +comment: Note that this function was formerly EC:2.4.1.204. +synonym: "UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.40] +synonym: "uridine diphosphoxylose-zeatin xylosyltransferase activity" EXACT [EC:2.4.2.40] +synonym: "zeatin O-b-D-xylosyltransferase activity" EXACT [] +synonym: "zeatin O-xylosyltransferase activity" EXACT [EC:2.4.2.40] +xref: EC:2.4.2.40 +xref: KEGG_REACTION:R02119 +xref: MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN +xref: RHEA:14721 +is_a: GO:0035252 ! UDP-xylosyltransferase activity + +[Term] +id: GO:0050405 +name: [acetyl-CoA carboxylase] kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." [EC:2.7.11.27, MetaCyc:[ACETYL-COA-CARBOXYLASE\]-KINASE-RXN] +synonym: "acetyl coenzyme A carboxylase kinase (phosphorylating) activity" EXACT [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase bound kinase activity" NARROW [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase (AMP-activated) activity" EXACT [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase (cAMP-independent) activity" EXACT [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase 2 activity" NARROW [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase activity" EXACT [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase-2 activity" NARROW [EC:2.7.11.27] +synonym: "acetyl-CoA carboxylase kinase-3 (AMP-activated) activity" NARROW [EC:2.7.11.27] +synonym: "acetyl-coenzyme A carboxylase kinase activity" EXACT [EC:2.7.11.27] +synonym: "ACK2" RELATED [EC:2.7.11.27] +synonym: "ACK3" RELATED [EC:2.7.11.27] +synonym: "AMPK" RELATED [EC:2.7.11.27] +synonym: "ATP:acetyl-CoA carboxylase phosphotransferase activity" EXACT [EC:2.7.11.27] +synonym: "I-peptide kinase activity" NARROW [EC:2.7.11.27] +synonym: "STK5" RELATED [EC:2.7.11.27] +xref: EC:2.7.11.27 +xref: MetaCyc:2.7.11.27-RXN +is_a: GO:0004672 ! protein kinase activity + +[Term] +id: GO:0050406 +name: [acetyl-CoA carboxylase]-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate." [EC:3.1.3.44, MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN] +synonym: "acetyl-CoA carboxylase-phosphatase activity" EXACT [EC:3.1.3.44] +synonym: "acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.44] +xref: EC:3.1.3.44 +xref: MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0050407 +name: [glycogen-synthase-D] phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate." [EC:3.1.3.42, MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN] +synonym: "glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "glycogen synthase D phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "glycogen synthase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "glycogen synthetase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "glycogen-synthase-D phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "Mg2+ dependent glycogen synthase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "phosphatase type 2oC" RELATED [EC:3.1.3.42] +synonym: "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity" EXACT [EC:3.1.3.42] +synonym: "UDP-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "UDPglucose-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] +synonym: "UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity" EXACT [EC:3.1.3.42] +synonym: "uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] +xref: EC:3.1.3.42 +xref: MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0050408 +name: [pyruvate kinase]-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate." [EC:3.1.3.49, MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN] +synonym: "ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.49] +synonym: "pyruvate kinase phosphatase activity" EXACT [EC:3.1.3.49] +synonym: "pyruvate kinase-phosphatase activity" EXACT [EC:3.1.3.49] +xref: EC:3.1.3.49 +xref: MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0050409 +name: indolylacetylinositol arabinosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP." [EC:2.4.2.34, RHEA:19505] +synonym: "arabinosylindolylacetylinositol synthase activity" EXACT [EC:2.4.2.34] +synonym: "UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity" EXACT [EC:2.4.2.34] +synonym: "UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity" EXACT [EC:2.4.2.34] +xref: EC:2.4.2.34 +xref: KEGG_REACTION:R04335 +xref: MetaCyc:2.4.2.34-RXN +xref: RHEA:19505 +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0052636 ! arabinosyltransferase activity + +[Term] +id: GO:0050410 +name: 3-oxolaurate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2)." [EC:4.1.1.56, RHEA:13385] +synonym: "3-oxododecanoate carboxy-lyase (2-undecanone-forming)" EXACT [EC:4.1.1.56] +synonym: "3-oxododecanoate carboxy-lyase activity" EXACT [EC:4.1.1.56] +synonym: "beta-ketoacyl decarboxylase activity" EXACT [EC:4.1.1.56] +synonym: "beta-ketolaurate decarboxylase activity" EXACT [EC:4.1.1.56] +xref: EC:4.1.1.56 +xref: KEGG_REACTION:R03747 +xref: MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN +xref: RHEA:13385 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050411 +name: agaritine gamma-glutamyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor." [EC:2.3.2.9, MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN] +synonym: "(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity" EXACT [EC:2.3.2.9] +synonym: "(gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity" EXACT [EC:2.3.2.9] +synonym: "agaritine g-glutamyltransferase activity" EXACT [] +xref: EC:2.3.2.9 +xref: MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0050412 +name: cinnamate beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP." [EC:2.4.1.177, RHEA:13437] +synonym: "cinnamate b-D-glucosyltransferase activity" EXACT [] +synonym: "cinnamate glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.177] +synonym: "UDPG:t-cinnamate glucosyltransferase activity" EXACT [EC:2.4.1.177] +synonym: "UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.177] +synonym: "uridine diphosphoglucose-cinnamate glucosyltransferase activity" EXACT [EC:2.4.1.177] +xref: EC:2.4.1.177 +xref: KEGG_REACTION:R02256 +xref: MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN +xref: RHEA:13437 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050413 +name: D-alanine 2-hydroxymethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine." [EC:2.1.2.7, RHEA:10064] +synonym: "2-methylserine hydroxymethyltransferase activity" EXACT [EC:2.1.2.7] +synonym: "5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity" EXACT [EC:2.1.2.7] +synonym: "D-alanine hydroxymethyltransferase activity" EXACT [] +xref: EC:2.1.2.7 +xref: KEGG_REACTION:R01225 +xref: MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN +xref: RHEA:10064 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0050414 +name: formimidoylaspartate deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3." [EC:3.5.3.5, MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN] +synonym: "formiminoaspartate deiminase activity" EXACT [] +synonym: "N-formimidoyl-L-aspartate iminohydrolase activity" EXACT [EC:3.5.3.5] +xref: EC:3.5.3.5 +xref: MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN +xref: RHEA:13661 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0050415 +name: formimidoylglutamase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide." [EC:3.5.3.8, RHEA:22492] +synonym: "formiminoglutamase activity" EXACT [] +synonym: "formiminoglutamate hydrolase activity" EXACT [EC:3.5.3.8] +synonym: "N-formimidoyl-L-glutamate formimidoylhydrolase activity" EXACT [EC:3.5.3.8] +synonym: "N-formimino-L-glutamate formiminohydrolase activity" EXACT [EC:3.5.3.8] +synonym: "N-formiminoglutamate hydrolase activity" EXACT [EC:3.5.3.8] +xref: EC:3.5.3.8 +xref: KEGG_REACTION:R02285 +xref: MetaCyc:FORMIMINOGLUTAMASE-RXN +xref: RHEA:22492 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0050416 +name: formimidoylglutamate deiminase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3." [EC:3.5.3.13, MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN] +synonym: "formiminoglutamate deiminase activity" EXACT [] +synonym: "formiminoglutamic iminohydrolase activity" EXACT [EC:3.5.3.13] +synonym: "N-formimidoyl-L-glutamate iminohydrolase activity" EXACT [EC:3.5.3.13] +xref: EC:3.5.3.13 +xref: MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN +xref: RHEA:22832 +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + +[Term] +id: GO:0050417 +name: glutamin-(asparagin-)ase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate." [EC:3.5.1.38, MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN] +synonym: "glutaminase-(asparagin-)ase activity" EXACT [] +synonym: "glutaminase-asparaginase activity" EXACT [EC:3.5.1.38] +synonym: "L-ASNase/L-GLNase activity" EXACT [EC:3.5.1.38] +synonym: "L-asparagine/L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.38] +synonym: "L-glutamine(L-asparagine) amidohydrolase activity" EXACT [EC:3.5.1.38] +xref: EC:3.5.1.38 +xref: MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050418 +name: hydroxylamine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor." [EC:1.7.99.1, MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN] +synonym: "ammonia:(acceptor) oxidoreductase activity" EXACT [EC:1.7.99.1] +synonym: "ammonia:acceptor oxidoreductase activity" EXACT [EC:1.7.99.1] +synonym: "hydroxylamine (acceptor) reductase activity" EXACT [EC:1.7.99.1] +xref: EC:1.7.99.1 +xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN +xref: RHEA:22052 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0050419 +name: hydroxymandelonitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate." [EC:4.1.2.11, MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN] +synonym: "(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)" EXACT [EC:4.1.2.11] +synonym: "(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity" EXACT [EC:4.1.2.11] +synonym: "hydroxynitrile lyase activity" BROAD [EC:4.1.2.11] +synonym: "sorghum hydroxynitrile lyase activity" EXACT [EC:4.1.2.11] +xref: EC:4.1.2.11 +xref: MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN +xref: RHEA:15977 +is_a: GO:0047606 ! hydroxynitrilase activity + +[Term] +id: GO:0050420 +name: maltose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate." [EC:2.4.1.139, MetaCyc:MALTOSE-SYNTHASE-RXN] +synonym: "alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating)" EXACT [EC:2.4.1.139] +xref: EC:2.4.1.139 +xref: MetaCyc:MALTOSE-SYNTHASE-RXN +xref: RHEA:22320 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050421 +name: nitrite reductase (NO-forming) activity +namespace: molecular_function +alt_id: GO:0016666 +def: "Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+." [EC:1.7.2.1, MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN] +comment: Note that EC:1.7.99.3 was merged into this term. +synonym: "[nitrite reductase (cytochrome)]" RELATED [EC:1.7.2.1] +synonym: "cd-cytochrome nitrite reductase activity" NARROW [EC:1.7.2.1] +synonym: "cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity" NARROW [EC:1.7.2.1] +synonym: "cytochrome c-551:O2, NO2+ oxidoreductase activity" EXACT [EC:1.7.2.1] +synonym: "cytochrome cd activity" NARROW [EC:1.7.2.1] +synonym: "cytochrome cd1 activity" NARROW [EC:1.7.2.1] +synonym: "methyl viologen-nitrite reductase activity" NARROW [EC:1.7.2.1] +synonym: "nitric-oxide:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.7.2.1] +synonym: "nitrite reductase (cytochrome; NO-forming) activity" EXACT [EC:1.7.2.1] +synonym: "NO-forming nitrite reductase (cytochrome) activity" EXACT [] +synonym: "NO-forming nitrite reductase activity" EXACT [] +synonym: "Pseudomonas cytochrome oxidase activity" NARROW [EC:1.7.2.1] +xref: EC:1.7.2.1 +xref: MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor +is_a: GO:0098809 ! nitrite reductase activity + +[Term] +id: GO:0050422 +name: strictosidine beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone." [EC:3.2.1.105, RHEA:12917] +synonym: "strictosidine b-glucosidase activity" EXACT [] +synonym: "strictosidine beta-D-glucohydrolase activity" EXACT [EC:3.2.1.105] +xref: EC:3.2.1.105 +xref: KEGG_REACTION:R03820 +xref: MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN +xref: RHEA:12917 +is_a: GO:0008422 ! beta-glucosidase activity + +[Term] +id: GO:0050423 +name: thiamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2." [EC:1.1.3.23, MetaCyc:THIAMIN-OXIDASE-RXN] +synonym: "thiamin dehydrogenase activity" EXACT [EC:1.1.3.23] +synonym: "thiamin oxidase activity" EXACT [] +synonym: "thiamin:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.23] +synonym: "thiamine dehydrogenase activity" EXACT [EC:1.1.3.23] +synonym: "thiamine:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.23] +xref: EC:1.1.3.23 +xref: MetaCyc:THIAMIN-OXIDASE-RXN +xref: RHEA:21280 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050424 +name: obsolete alanine carboxypeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups." [EC:3.4.17.6, MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "alanine carboxypeptidase activity" EXACT [] +synonym: "N-benzoyl-L-alanine-amidohydrolase activity" EXACT [EC:3.4.17.6] +xref: EC:3.4.17.6 +xref: MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0050425 +name: obsolete carboxypeptidase B activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid." [EC:3.4.17.2, MetaCyc:CARBOXYPEPTIDASE-B-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxypeptidase B activity" EXACT [] +synonym: "pancreatic carboxypeptidase B" RELATED [EC:3.4.17.2] +synonym: "peptidyl-L-lysine [L-arginine]hydrolase activity" EXACT [EC:3.4.17.2] +synonym: "protaminase activity" RELATED [EC:3.4.17.2] +synonym: "tissue carboxypeptidase B" RELATED [EC:3.4.17.2] +xref: EC:3.4.17.2 +xref: MetaCyc:CARBOXYPEPTIDASE-B-RXN +is_obsolete: true +replaced_by: GO:0004181 + +[Term] +id: GO:0050426 +name: obsolete peptidyl-glycinamidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide." [EC:3.4.19.2, MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN] +comment: This term was made obsolete because it represents a gene product. +synonym: "carboxamidopeptidase activity" EXACT [EC:3.4.19.2] +synonym: "carboxyamidase activity" EXACT [EC:3.4.19.2] +synonym: "peptidyl amino acid amide hydrolase activity" EXACT [EC:3.4.19.2] +synonym: "peptidyl carboxy-amidase activity" EXACT [EC:3.4.19.2] +synonym: "peptidyl carboxyamidase activity" EXACT [EC:3.4.19.2] +synonym: "peptidyl-glycinamidase activity" EXACT [] +xref: EC:3.4.19.2 +xref: MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN +is_obsolete: true +replaced_by: GO:0008242 + +[Term] +id: GO:0050427 +name: 3'-phosphoadenosine 5'-phosphosulfate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems." [ISBN:0198506732] +synonym: "3'-phosphoadenosine 5'-phosphosulfate metabolism" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulphate metabolic process" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulphate metabolism" EXACT [] +synonym: "3'-phosphoadenylyl-sulfate metabolic process" EXACT [] +synonym: "3'-phosphoadenylyl-sulfate metabolism" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate metabolic process" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate metabolism" EXACT [] +synonym: "PAPS metabolic process" EXACT [] +synonym: "PAPS metabolism" EXACT [] +synonym: "phosphoadenosine phosphosulfate metabolic process" EXACT [] +synonym: "phosphoadenosine phosphosulfate metabolism" EXACT [] +xref: MetaCyc:PWY-5340 +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0034035 ! purine ribonucleoside bisphosphate metabolic process +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0050428 +name: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems." [ISBN:0198506732] +synonym: "3'-phosphoadenosine 5'-phosphosulfate anabolism" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulfate biosynthesis" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulfate formation" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulfate synthesis" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulphate biosynthesis" EXACT [] +synonym: "3'-phosphoadenosine 5'-phosphosulphate biosynthetic process" EXACT [] +synonym: "3'-phosphoadenylyl-sulfate biosynthesis" EXACT [] +synonym: "3'-phosphoadenylyl-sulfate biosynthetic process" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate biosynthesis" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate biosynthetic process" EXACT [] +synonym: "PAPS biosynthesis" EXACT [] +synonym: "PAPS biosynthetic process" EXACT [] +synonym: "phosphoadenosine phosphosulfate biosynthesis" EXACT [] +synonym: "phosphoadenosine phosphosulfate biosynthetic process" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0034036 ! purine ribonucleoside bisphosphate biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0050427 ! 3'-phosphoadenosine 5'-phosphosulfate metabolic process + +[Term] +id: GO:0050429 +name: calcium-dependent phospholipase C activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+." [EC:3.1.4.3] +is_a: GO:0004629 ! phospholipase C activity + +[Term] +id: GO:0050431 +name: transforming growth factor beta binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types." [ISBN:0198506732] +synonym: "TGF-beta binding" EXACT [] +synonym: "TGFbeta binding" EXACT [] +synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] +synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] +is_a: GO:0019838 ! growth factor binding +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0050432 +name: catecholamine secretion +namespace: biological_process +def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef] +is_a: GO:0032940 ! secretion by cell +is_a: GO:0051937 ! catecholamine transport + +[Term] +id: GO:0050433 +name: regulation of catecholamine secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] +is_a: GO:0051952 ! regulation of amine transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050432 ! catecholamine secretion +relationship: regulates GO:0050432 ! catecholamine secretion + +[Term] +id: GO:0050434 +name: positive regulation of viral transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral transcription." [GOC:ai] +synonym: "activation of viral transcription" NARROW [] +synonym: "stimulation of viral transcription" NARROW [] +synonym: "up regulation of viral transcription" EXACT [] +synonym: "up-regulation of viral transcription" EXACT [] +synonym: "upregulation of viral transcription" EXACT [] +is_a: GO:0046782 ! regulation of viral transcription +is_a: GO:0048524 ! positive regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019083 ! viral transcription +relationship: positively_regulates GO:0019083 ! viral transcription + +[Term] +id: GO:0050435 +name: amyloid-beta metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP)." [GOC:ai] +synonym: "amyloid-beta metabolism" EXACT [] +synonym: "beta-amyloid metabolic process" EXACT [] +synonym: "beta-amyloid metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process + +[Term] +id: GO:0050436 +name: microfibril binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material." [GOC:ai] +comment: See also the cellular component term 'microfibril ; GO:0001527'. +is_a: GO:0005488 ! binding + +[Term] +id: GO:0050437 +name: (-)-endo-fenchol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate." [EC:4.2.3.10, RHEA:20565] +synonym: "(-)-endo-fenchol cyclase activity" EXACT [EC:4.2.3.10] +synonym: "geranyl pyrophosphate:(-)-endo-fenchol cyclase activity" EXACT [EC:4.2.3.10] +synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]" RELATED [EC:4.2.3.10] +xref: EC:4.2.3.10 +xref: KEGG_REACTION:R02004 +xref: MetaCyc:4.2.3.10-RXN +xref: RHEA:20565 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0050438 +name: 2-ethylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+)." [EC:2.3.3.6, RHEA:23040] +synonym: "(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.6] +synonym: "2-ethylmalate-3-hydroxybutanedioate synthase activity" EXACT [EC:2.3.3.6] +synonym: "acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.6] +synonym: "propylmalate synthase activity" EXACT [EC:2.3.3.6] +synonym: "propylmalic synthase activity" EXACT [EC:2.3.3.6] +xref: EC:2.3.3.6 +xref: KEGG_REACTION:R00998 +xref: MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN +xref: RHEA:23040 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050439 +name: 2-hydroxy-3-oxoadipate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2)." [EC:2.2.1.5, RHEA:14341] +synonym: "2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity" EXACT [EC:2.2.1.5] +synonym: "2-hydroxy-3-oxoadipate synthetase activity" EXACT [EC:2.2.1.5] +synonym: "2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.5] +synonym: "alpha-ketoglutaric-glyoxylic carboligase activity" EXACT [EC:2.2.1.5] +synonym: "oxoglutarate: glyoxylate carboligase activity" EXACT [EC:2.2.1.5] +synonym: "oxoglutarate:glyoxylate carboligase activity" EXACT [EC:2.2.1.5] +xref: EC:2.2.1.5 +xref: KEGG_REACTION:R00474 +xref: MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN +xref: RHEA:14341 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0050440 +name: 2-methylcitrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+)." [EC:2.3.3.5, RHEA:23780] +synonym: "2-methylcitrate oxaloacetate-lyase activity" EXACT [EC:2.3.3.5] +synonym: "MCS activity" EXACT [EC:2.3.3.5] +synonym: "methylcitrate synthase activity" EXACT [EC:2.3.3.5] +synonym: "methylcitrate synthetase activity" EXACT [EC:2.3.3.5] +synonym: "propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)" EXACT [EC:2.3.3.5] +xref: EC:2.3.3.5 +xref: KEGG_REACTION:R00931 +xref: MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN +xref: RHEA:23780 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050441 +name: 3-ethylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+)." [EC:2.3.3.7, RHEA:10500] +synonym: "2-ethyl-3-hydroxybutanedioate synthase activity" EXACT [EC:2.3.3.7] +synonym: "3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity" EXACT [EC:2.3.3.7] +synonym: "butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)" EXACT [EC:2.3.3.7] +xref: EC:2.3.3.7 +xref: KEGG_REACTION:R01180 +xref: MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN +xref: RHEA:10500 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050442 +name: 3-propylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+)." [EC:2.3.3.12, RHEA:14457] +synonym: "3-(n-propyl)-malate synthase activity" EXACT [EC:2.3.3.12] +synonym: "3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity" EXACT [EC:2.3.3.12] +synonym: "beta-n-propylmalate synthase activity" EXACT [EC:2.3.3.12] +synonym: "N-propylmalate synthase activity" EXACT [EC:2.3.3.12] +synonym: "pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)" EXACT [EC:2.3.3.12] +xref: EC:2.3.3.12 +xref: KEGG_REACTION:R03040 +xref: MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN +xref: RHEA:14457 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050444 +name: aquacobalamin reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+." [EC:1.16.1.5, MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN] +synonym: "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity" EXACT [EC:1.16.1.5] +synonym: "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.16.1.5] +synonym: "cob(II)alamin:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.5] +synonym: "NADPH-linked aquacobalamin reductase activity" EXACT [EC:1.16.1.5] +synonym: "NADPH2:aquacob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.5] +synonym: "NADPH:aquacob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.5] +xref: EC:1.16.1.5 +xref: MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN +xref: RHEA:20752 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0050445 +name: asparagusate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH." [EC:1.8.1.11, RHEA:14881] +synonym: "3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.11] +synonym: "asparagusate dehydrogenase activity" EXACT [EC:1.8.1.11] +synonym: "asparagusate reductase (NADH) activity" EXACT [] +synonym: "asparagusate reductase (NADH2)" EXACT [EC:1.8.1.11] +synonym: "asparagusic dehydrogenase activity" EXACT [EC:1.8.1.11] +synonym: "NADH2:asparagusate oxidoreductase activity" EXACT [EC:1.8.1.11] +synonym: "NADH:asparagusate oxidoreductase activity" EXACT [EC:1.8.1.11] +xref: EC:1.8.1.11 +xref: KEGG_REACTION:R03761 +xref: MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN +xref: RHEA:14881 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050446 +name: azobenzene reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+." [EC:1.7.1.6, MetaCyc:AZOBENZENE-REDUCTASE-RXN] +synonym: "azo reductase activity" BROAD [EC:1.7.1.6] +synonym: "azo-dye reductase activity" BROAD [EC:1.7.1.6] +synonym: "azoreductase activity" BROAD [EC:1.7.1.6] +synonym: "dibromopropylaminophenylazobenzoic azoreductase activity" EXACT [EC:1.7.1.6] +synonym: "dimethylaminobenzene reductase activity" EXACT [EC:1.7.1.6] +synonym: "methyl red azoreductase activity" NARROW [EC:1.7.1.6] +synonym: "N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.6] +synonym: "N,N-dimethyl-4-phenylazoaniline azoreductase activity" EXACT [EC:1.7.1.6] +synonym: "NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity" EXACT [EC:1.7.1.6] +synonym: "NADPH-dependent azoreductase activity" BROAD [EC:1.7.1.6] +synonym: "NADPH2-dependent azoreductase activity" EXACT [EC:1.7.1.6] +synonym: "NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity" EXACT [EC:1.7.1.6] +synonym: "NADPH:4-(dimethylamino)azobenzene oxidoreductase activity" EXACT [EC:1.7.1.6] +synonym: "NC-reductase activity" NARROW [EC:1.7.1.6] +synonym: "new coccine (NC)-reductase" RELATED [EC:1.7.1.6] +synonym: "New coccine (NC)-reductase activity" NARROW [EC:1.7.1.6] +synonym: "nicotinamide adenine dinucleotide (phosphate) azoreductase activity" EXACT [EC:1.7.1.6] +synonym: "orange I azoreductase activity" NARROW [EC:1.7.1.6] +synonym: "orange II azoreductase activity" NARROW [EC:1.7.1.6] +synonym: "p-aminoazobenzene reductase activity" EXACT [EC:1.7.1.6] +synonym: "p-dimethylaminoazobenzene azoreductase activity" EXACT [EC:1.7.1.6] +xref: EC:1.7.1.6 +xref: MetaCyc:AZOBENZENE-REDUCTASE-RXN +xref: RHEA:16269 +xref: UM-BBD_reactionID:r0808 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0050447 +name: zeatin 9-aminocarboxyethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+)." [EC:2.5.1.50, RHEA:17333] +synonym: "3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.50] +synonym: "beta-(9-cytokinin)-alanine synthase activity" EXACT [] +synonym: "beta-(9-cytokinin)alanine synthase activity" EXACT [EC:2.5.1.50] +synonym: "lupinate synthetase activity" EXACT [EC:2.5.1.50] +synonym: "lupinic acid synthase activity" EXACT [EC:2.5.1.50] +synonym: "lupinic acid synthetase activity" EXACT [EC:2.5.1.50] +synonym: "O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity" EXACT [EC:2.5.1.50] +synonym: "O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)" EXACT [EC:2.5.1.50] +synonym: "O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.50] +xref: EC:2.5.1.50 +xref: KEGG_REACTION:R03133 +xref: MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN +xref: RHEA:17333 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050448 +name: beta-cyclopiazonate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2)." [EC:1.21.99.1, RHEA:14526] +synonym: "b-cyclopiazonate dehydrogenase activity" EXACT [] +synonym: "beta-cyclopiazonate oxidocyclase activity" EXACT [EC:1.21.99.1] +synonym: "beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)" EXACT [EC:1.21.99.1] +synonym: "beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)" EXACT [EC:1.21.99.1] +synonym: "beta-cyclopiazonic oxidocyclase activity" EXACT [EC:1.21.99.1] +xref: EC:1.21.99.1 +xref: KEGG_REACTION:R04080 +xref: MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN +xref: RHEA:14526 +is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond + +[Term] +id: GO:0050449 +name: casbene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate." [EC:4.2.3.8, RHEA:14901] +synonym: "casbene synthetase activity" EXACT [EC:4.2.3.8] +synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.8] +synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)" EXACT [EC:4.2.3.8] +xref: EC:4.2.3.8 +xref: KEGG_REACTION:R02064 +xref: MetaCyc:CASBENE-SYNTHASE-RXN +xref: RHEA:14901 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0050450 +name: citrate (Re)-synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group." [EC:2.3.3.3, ISBN:0121227073, MetaCyc:CITRATE-RE-SYNTHASE-RXN] +synonym: "(R)-citrate synthase activity" EXACT [EC:2.3.3.3] +synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]" RELATED [EC:2.3.3.3] +synonym: "citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.3] +synonym: "citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]" RELATED [EC:2.3.3.3] +synonym: "Re-citrate-synthase activity" EXACT [EC:2.3.3.3] +xref: EC:2.3.3.3 +xref: MetaCyc:CITRATE-RE-SYNTHASE-RXN +is_a: GO:0036440 ! citrate synthase activity + +[Term] +id: GO:0050451 +name: CoA-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+." [EC:1.8.1.14, MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN] +synonym: "CoA-disulfide reductase (NAD(P)H) activity" RELATED [EC:1.8.1.14] +synonym: "CoA-disulfide reductase (NADH) activity" EXACT [] +synonym: "CoA-disulfide reductase (NADH2)" EXACT [EC:1.8.1.14] +synonym: "CoA-disulfide reductase [NAD(P)H]" RELATED [EC:1.8.1.14] +synonym: "CoA-disulphide reductase activity" EXACT [] +synonym: "CoA:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.14] +synonym: "CoA:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.14] +synonym: "CoADR activity" EXACT [EC:1.8.1.14] +synonym: "coenzyme A disulfide reductase activity" EXACT [EC:1.8.1.14] +synonym: "NADH2:CoA-disulfide oxidoreductase activity" EXACT [EC:1.8.1.14] +synonym: "NADH:CoA-disulfide oxidoreductase activity" EXACT [EC:1.8.1.14] +xref: EC:1.8.1.14 +xref: MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN +is_a: GO:0015036 ! disulfide oxidoreductase activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050452 +name: CoA-glutathione reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+." [EC:1.8.1.10, MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN] +synonym: "CoA-glutathione reductase (NADPH) activity" EXACT [] +synonym: "coenzyme A disulfide-glutathione reductase activity" EXACT [EC:1.8.1.10] +synonym: "coenzyme A glutathione disulfide reductase activity" EXACT [EC:1.8.1.10] +synonym: "glutathione:NADP+ oxidoreductase (CoA-acylating)" EXACT [EC:1.8.1.10] +synonym: "NADPH-dependent coenzyme A-SS-glutathione reductase activity" EXACT [EC:1.8.1.10] +synonym: "NADPH2:CoA-glutathione oxidoreductase activity" EXACT [EC:1.8.1.10] +synonym: "NADPH:CoA-glutathione oxidoreductase activity" EXACT [EC:1.8.1.10] +xref: EC:1.8.1.10 +xref: MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN +xref: RHEA:14617 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050453 +name: cob(II)alamin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH." [EC:1.16.1.4, RHEA:17481] +synonym: "B(12r) reductase activity" EXACT [EC:1.16.1.4] +synonym: "B12r reductase activity" EXACT [EC:1.16.1.4] +synonym: "cob(I)alamin:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.4] +synonym: "NADH2:cob(II)alamin oxidoreductase activity" EXACT [EC:1.16.1.4] +synonym: "NADH:cob(II)alamin oxidoreductase activity" EXACT [EC:1.16.1.4] +synonym: "vitamin B(12r) reductase activity" EXACT [EC:1.16.1.4] +synonym: "vitamin B12 reductase activity" EXACT [] +synonym: "vitamin B12 reduction" RELATED [] +synonym: "vitamin B12r reductase activity" EXACT [EC:1.16.1.4] +xref: EC:1.16.1.4 +xref: KEGG_REACTION:R00099 +xref: MetaCyc:COBIIALAMIN-REDUCTASE-RXN +xref: Reactome:R-HSA-3149560 "Unknown reductase reduces cob(II)alamin to cob(I)alamin" +xref: RHEA:17481 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor + +[Term] +id: GO:0050454 +name: coenzyme F420 hydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420." [EC:1.12.98.1, RHEA:23760] +synonym: "8-hydroxy-5-deazaflavin-reducing hydrogenase activity" EXACT [EC:1.12.98.1] +synonym: "coenzyme F420-dependent hydrogenase activity" EXACT [EC:1.12.98.1] +synonym: "F420-reducing hydrogenase activity" EXACT [EC:1.12.98.1] +synonym: "hydrogen:coenzyme F420 oxidoreductase activity" EXACT [EC:1.12.98.1] +xref: EC:1.12.98.1 +xref: KEGG_REACTION:R03025 +xref: MetaCyc:COENZYME-F420-HYDROGENASE-RXN +xref: RHEA:23760 +is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors + +[Term] +id: GO:0050455 +name: columbamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O." [EC:1.21.3.2, RHEA:23564] +synonym: "berberine synthase activity" EXACT [EC:1.21.3.2] +synonym: "columbamine:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.21.3.2] +xref: EC:1.21.3.2 +xref: KEGG_REACTION:R00044 +xref: MetaCyc:COLUMBAMINE-OXIDASE-RXN +xref: RHEA:23564 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0050456 +name: cystine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH." [EC:1.8.1.6, RHEA:20597] +synonym: "cystine reductase (NADH) activity" EXACT [EC:1.8.1.6] +synonym: "cystine reductase (NADH2)" EXACT [EC:1.8.1.6] +synonym: "L-cysteine:NAD+ oxidoreductase" EXACT [EC:1.8.1.6] +synonym: "NADH-dependent cystine reductase activity" EXACT [EC:1.8.1.6] +synonym: "NADH2:L-cystine oxidoreductase" EXACT [EC:1.8.1.6] +synonym: "NADH:L-cystine oxidoreductase activity" EXACT [EC:1.8.1.6] +xref: EC:1.8.1.6 +xref: KEGG_REACTION:R00892 +xref: MetaCyc:CYSTINE-REDUCTASE-NADH-RXN +xref: RHEA:20597 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050457 +name: decylcitrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+)." [EC:2.3.3.2, RHEA:16605] +synonym: "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity" EXACT [EC:2.3.3.2] +synonym: "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating)" EXACT [EC:2.3.3.2] +synonym: "2-decylcitrate synthase activity" EXACT [EC:2.3.3.2] +synonym: "dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)" EXACT [EC:2.3.3.2] +xref: EC:2.3.3.2 +xref: KEGG_REACTION:R03735 +xref: MetaCyc:DECYLCITRATE-SYNTHASE-RXN +xref: RHEA:16605 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050458 +name: decylhomocitrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+)." [EC:2.3.3.4, RHEA:10364] +synonym: "2-decylhomocitrate synthase activity" EXACT [EC:2.3.3.4] +synonym: "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity" EXACT [EC:2.3.3.4] +synonym: "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)" EXACT [EC:2.3.3.4] +synonym: "dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)" EXACT [EC:2.3.3.4] +xref: EC:2.3.3.4 +xref: KEGG_REACTION:R03859 +xref: MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN +xref: RHEA:10364 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050459 +name: ethanolamine-phosphate phospho-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate." [EC:4.2.3.2, RHEA:17889] +synonym: "amino alcohol O-phosphate phospholyase activity" BROAD [EC:4.2.3.2] +synonym: "ethanolamine-phosphate phospho-lyase (deaminating)" EXACT [EC:4.2.3.2] +synonym: "ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)" EXACT [EC:4.2.3.2] +synonym: "O-phosphoethanolamine-phospholyase activity" EXACT [EC:4.2.3.2] +synonym: "O-phosphorylethanol-amine phospho-lyase activity" EXACT [EC:4.2.3.2] +xref: EC:4.2.3.2 +xref: KEGG_REACTION:R00748 +xref: MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN +xref: Reactome:R-HSA-5696415 "ETNPPL tetramer hydrolyses PETA" +xref: RHEA:17889 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0050460 +name: hydroxylamine reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+." [EC:1.7.1.10, MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN] +synonym: "ammonium dehydrogenase activity" EXACT [EC:1.7.1.10] +synonym: "ammonium:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.10] +synonym: "hydroxylamine reductase (NADH2)" EXACT [EC:1.7.1.10] +synonym: "N-hydroxy amine reductase activity" EXACT [EC:1.7.1.10] +synonym: "NADH-hydroxylamine reductase activity" EXACT [EC:1.7.1.10] +synonym: "NADH2:hydroxylamine oxidoreductase activity" EXACT [EC:1.7.1.10] +synonym: "NADH:hydroxylamine oxidoreductase activity" EXACT [EC:1.7.1.10] +xref: EC:1.7.1.10 +xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN +xref: RHEA:20581 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0050461 +name: L-mimosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate." [EC:2.5.1.52, RHEA:12693] +synonym: "3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.52] +synonym: "O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity" EXACT [EC:2.5.1.52] +synonym: "O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)" EXACT [EC:2.5.1.52] +synonym: "O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.52] +xref: EC:2.5.1.52 +xref: KEGG_REACTION:R04091 +xref: MetaCyc:RXN-7461 +xref: RHEA:12693 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050462 +name: N-acetylneuraminate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate." [EC:2.5.1.56, MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN] +synonym: "(NANA)condensing enzyme activity" EXACT [EC:2.5.1.56] +synonym: "N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.56] +synonym: "N-acetylneuraminic acid synthase activity" EXACT [EC:2.5.1.56] +synonym: "NeuAc synthase activity" EXACT [EC:2.5.1.56] +synonym: "phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.56] +xref: EC:2.5.1.56 +xref: MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN +xref: RHEA:19273 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050463 +name: nitrate reductase [NAD(P)H] activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+." [EC:1.7.1.2, MetaCyc:NITRATE-REDUCTASE-NADPH-RXN] +synonym: "assimilatory NAD(P)H-nitrate reductase activity" RELATED [EC:1.7.1.2] +synonym: "assimilatory nitrate reductase activity" RELATED [EC:1.7.1.2] +synonym: "NAD(P)H bispecific nitrate reductase activity" EXACT [EC:1.7.1.2] +synonym: "NAD(P)H-nitrate reductase activity" EXACT [EC:1.7.1.2] +synonym: "NAD(P)H2:nitrate oxidoreductase activity" EXACT [EC:1.7.1.2] +synonym: "NAD(P)H:nitrate oxidoreductase activity" EXACT [EC:1.7.1.2] +synonym: "nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.7.1.2] +synonym: "nitrate reductase [NAD(P)H2]" RELATED [EC:1.7.1.2] +synonym: "nitrate reductase NAD(P)H activity" EXACT [EC:1.7.1.2] +synonym: "nitrite:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.2] +xref: EC:1.7.1.2 +is_a: GO:0008940 ! nitrate reductase activity +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0050464 +name: nitrate reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+." [EC:1.7.1.3, MetaCyc:NITRATE-REDUCTASE-NADPH-RXN] +synonym: "assimilatory NADPH-nitrate reductase activity" EXACT [EC:1.7.1.3] +synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.1.3] +synonym: "assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity" EXACT [EC:1.7.1.3] +synonym: "NADPH-nitrate reductase activity" EXACT [EC:1.7.1.3] +synonym: "NADPH:nitrate oxidoreductase activity" EXACT [EC:1.7.1.3] +synonym: "NADPH:nitrate reductase activity" EXACT [EC:1.7.1.3] +synonym: "nitrate reductase (NADPH(2)) activity" EXACT [EC:1.7.1.3] +synonym: "nitrate reductase (NADPH2)" EXACT [EC:1.7.1.3] +synonym: "nitrite:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.3] +synonym: "triphosphopyridine nucleotide-nitrate reductase activity" EXACT [EC:1.7.1.3] +xref: EC:1.7.1.3 +xref: MetaCyc:NITRATE-REDUCTASE-NADPH-RXN +xref: RHEA:19061 +is_a: GO:0050463 ! nitrate reductase [NAD(P)H] activity + +[Term] +id: GO:0050465 +name: nitroquinoline-N-oxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+." [EC:1.7.1.9, MetaCyc:1.7.1.9-RXN] +synonym: "4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.9] +synonym: "4-nitroquinoline 1-oxide reductase activity" EXACT [EC:1.7.1.9] +synonym: "4NQO reductase activity" EXACT [EC:1.7.1.9] +synonym: "NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity" EXACT [EC:1.7.1.9] +synonym: "NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity" EXACT [EC:1.7.1.9] +xref: EC:1.7.1.9 +xref: MetaCyc:1.7.1.9-RXN +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0050466 +name: obsolete oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors" EXACT [] +is_obsolete: true +consider: GO:0046992 + +[Term] +id: GO:0050467 +name: pentalenene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene." [EC:4.2.3.7, RHEA:18081] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)" EXACT [EC:4.2.3.7] +synonym: "2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)" EXACT [EC:4.2.3.7] +synonym: "pentalenene synthetase activity" EXACT [EC:4.2.3.7] +xref: EC:4.2.3.7 +xref: KEGG_REACTION:R02305 +xref: MetaCyc:PENTALENENE-SYNTHASE-RXN +xref: RHEA:18081 +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0050468 +name: reticuline oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+)." [EC:1.21.3.3, RHEA:19885] +synonym: "(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)" EXACT [EC:1.21.3.3] +synonym: "BBE" RELATED [EC:1.21.3.3] +synonym: "berberine bridge enzyme activity" EXACT [EC:1.21.3.3] +synonym: "berberine-bridge-forming enzyme activity" EXACT [EC:1.21.3.3] +synonym: "tetrahydroprotoberberine synthase activity" EXACT [EC:1.21.3.3] +xref: EC:1.21.3.3 +xref: KEGG_REACTION:R03831 +xref: MetaCyc:RETICULINE-OXIDASE-RXN +xref: RHEA:19885 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0050469 +name: sabinene-hydrate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate." [EC:4.2.3.11, RHEA:19565] +synonym: "geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)" EXACT [EC:4.2.3.11] +synonym: "sabinene hydrate cyclase activity" EXACT [EC:4.2.3.11] +xref: EC:4.2.3.11 +xref: KEGG_REACTION:R02006 +xref: MetaCyc:4.2.3.11-RXN +xref: RHEA:19565 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0050470 +name: trimethylamine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein." [EC:1.5.8.2, MetaCyc:1.5.8.2-RXN] +synonym: "TMADh activity" RELATED [EC:1.5.8.2] +synonym: "trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)" EXACT [EC:1.5.8.2] +xref: EC:1.5.8.2 +xref: MetaCyc:1.5.8.2-RXN +xref: UM-BBD_enzymeID:e0854 +is_a: GO:0046997 ! oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor + +[Term] +id: GO:0050471 +name: uracilylalanine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate." [EC:2.5.1.53, MetaCyc:URACILYLALANINE-SYNTHASE-RXN] +synonym: "3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.53] +synonym: "isowillardiine synthase activity" EXACT [EC:2.5.1.53] +synonym: "O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity" EXACT [EC:2.5.1.53] +synonym: "O3-acetyl-L-serine acetate-lyase (adding uracil)" EXACT [EC:2.5.1.53] +synonym: "O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.53] +synonym: "Willardiine synthase activity" EXACT [EC:2.5.1.53] +xref: EC:2.5.1.53 +xref: MetaCyc:URACILYLALANINE-SYNTHASE-RXN +xref: RHEA:11496 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050472 +name: zeatin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin." [EC:1.3.1.69, RHEA:12757] +synonym: "dihydrozeatin:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.69] +xref: EC:1.3.1.69 +xref: KEGG_REACTION:R05702 +xref: MetaCyc:ZEATIN-REDUCTASE-RXN +xref: RHEA:12757 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050473 +name: arachidonate 15-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate." [EC:1.13.11.33] +synonym: "15-lipoxygenase activity" EXACT [EC:1.13.11.33] +synonym: "arachidonate omega(6) lipoxygenase activity" EXACT [EC:1.13.11.33] +synonym: "arachidonate omega6 lipoxygenase activity" EXACT [EC:1.13.11.33] +synonym: "arachidonate:oxygen 15-oxidoreductase activity" EXACT [EC:1.13.11.33] +synonym: "linoleic acid omega6-lipoxygenase activity" EXACT [EC:1.13.11.33] +synonym: "omega6 lipoxygenase activity" EXACT [EC:1.13.11.33] +xref: EC:1.13.11.33 +xref: MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN +xref: Reactome:R-HSA-2161951 "Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2" +xref: Reactome:R-HSA-2162002 "Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B" +xref: Reactome:R-HSA-9018907 "ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3" +xref: Reactome:R-HSA-9020261 "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA" +xref: Reactome:R-HSA-9020262 "ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA" +xref: Reactome:R-HSA-9020275 "ALOX15 oxidises DHA to 17(S)-Hp-DHA" +xref: Reactome:R-HSA-9020610 "ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3" +xref: Reactome:R-HSA-9024872 "ALOX15 oxidises 17(S)-Hp-DHA to PDX" +xref: Reactome:R-HSA-9024881 "ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA" +xref: Reactome:R-HSA-9025152 "ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6" +xref: Reactome:R-HSA-9026003 "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3" +xref: Reactome:R-HSA-9027532 "PTGS2 dimer oxidises DHA to 13-HDHA" +xref: Reactome:R-HSA-9027607 "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3" +xref: Reactome:R-HSA-9027627 "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)" +xref: Reactome:R-HSA-9028255 "PTGS2 dimer oxidises EPA to PGH3" +xref: RHEA:16869 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050474 +name: (S)-norcoclaurine synthase activity +namespace: molecular_function +alt_id: GO:0050475 +def: "Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O." [EC:4.2.1.78] +synonym: "(S)-norlaudanosoline synthase activity" EXACT [EC:4.2.1.78] +synonym: "4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine)" EXACT [EC:4.2.1.78] +synonym: "4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]" RELATED [EC:4.2.1.78] +xref: EC:4.2.1.78 +xref: MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN +xref: RHEA:16173 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050476 +name: acetylenedicarboxylate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate." [EC:4.1.1.78] +synonym: "acetylenedicarboxylate carboxy-lyase (pyruvate-forming)" EXACT [EC:4.1.1.78] +synonym: "acetylenedicarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.78] +synonym: "acetylenedicarboxylate hydrase activity" EXACT [EC:4.1.1.78] +synonym: "acetylenedicarboxylate hydratase activity" EXACT [EC:4.1.1.78] +xref: EC:4.1.1.78 +xref: MetaCyc:4.1.1.78-RXN +xref: RHEA:17733 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050477 +name: acyl-lysine deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate." [EC:3.5.1.17] +synonym: "6-N-acyl-L-lysine amidohydrolase activity" EXACT [EC:3.5.1.17] +synonym: "epsilon-lysine acylase activity" EXACT [EC:3.5.1.17] +synonym: "N6-acyl-L-lysine amidohydrolase activity" EXACT [EC:3.5.1.17] +xref: EC:3.5.1.17 +xref: MetaCyc:ACYL-LYSINE-DEACYLASE-RXN +xref: RHEA:24548 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050478 +name: anthranilate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O." [EC:1.14.16.3, RHEA:21168] +synonym: "anthranilate 3-hydroxylase activity" EXACT [] +synonym: "anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.16.3] +synonym: "anthranilic acid hydroxylase activity" BROAD [EC:1.14.16.3] +synonym: "anthranilic hydroxylase activity" BROAD [EC:1.14.16.3] +xref: EC:1.14.16.3 +xref: KEGG_REACTION:R01816 +xref: MetaCyc:1.14.16.3-RXN +xref: RHEA:21168 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050479 +name: glyceryl-ether monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine)." [EC:1.14.16.5, MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN] +synonym: "1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity" EXACT [EC:1.14.16.5] +synonym: "alkylglycerol monooxygenase activity" EXACT [EC:1.14.16.5] +synonym: "glyceryl ether oxygenase activity" EXACT [EC:1.14.16.5] +synonym: "glyceryl etherase activity" EXACT [EC:1.14.16.5] +synonym: "glyceryl-ether cleaving enzyme activity" EXACT [EC:1.14.16.5] +synonym: "O-alkylglycerol monooxygenase activity" EXACT [EC:1.14.16.5] +xref: EC:1.14.16.5 +xref: MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN +xref: Reactome:R-HSA-5696119 "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol" +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050480 +name: imidazolonepropionase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+)." [EC:3.5.2.7, RHEA:23660] +synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity" EXACT [EC:3.5.2.7] +synonym: "4(5)-imidazolone-5(4)-propionic acid hydrolase activity" EXACT [EC:3.5.2.7] +synonym: "imidazolone propionic acid hydrolase activity" EXACT [EC:3.5.2.7] +synonym: "imidazolone-5-propionate hydrolase activity" EXACT [EC:3.5.2.7] +xref: EC:3.5.2.7 +xref: KEGG_REACTION:R02288 +xref: MetaCyc:IMIDAZOLONEPROPIONASE-RXN +xref: RHEA:23660 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0050481 +name: mandelate 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate." [EC:1.14.16.6, RHEA:21716] +synonym: "(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.16.6] +synonym: "L-mandelate 4-hydroxylase activity" EXACT [] +synonym: "mandelic acid 4-hydroxylase activity" EXACT [EC:1.14.16.6] +xref: EC:1.14.16.6 +xref: KEGG_REACTION:R03794 +xref: MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN +xref: RHEA:21716 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050482 +name: arachidonic acid secretion +namespace: biological_process +def: "The controlled release of arachidonic acid from a cell or a tissue." [GOC:ai] +comment: This term should be used to annotate release of arachidonic acid from the cell. For the hydrolytic release of arachidonic acid from a phospholipid, consider instead annotating to 'phospholipase A2 activity ; GO:0004623'. +is_a: GO:0032309 ! icosanoid secretion +is_a: GO:1903963 ! arachidonate transport + +[Term] +id: GO:0050483 +name: IMP 5'-nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate." [GOC:ai] +synonym: "IMP 5' nucleotidase activity" EXACT [] +synonym: "IMP-GMP specific 5'-nucleotidase activity" RELATED [] +xref: MetaCyc:RXN-7607 +is_a: GO:0008253 ! 5'-nucleotidase activity + +[Term] +id: GO:0050484 +name: GMP 5'-nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate." [GOC:ai] +synonym: "GMP 5' nucleotidase activity" EXACT [] +synonym: "IMP-GMP specific 5'-nucleotidase activity" RELATED [] +xref: MetaCyc:RXN-7609 +is_a: GO:0008253 ! 5'-nucleotidase activity + +[Term] +id: GO:0050485 +name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide." [GOC:ai] +synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor" EXACT [] +xref: EC:1.21.4 +is_a: GO:0046992 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond + +[Term] +id: GO:0050486 +name: intramolecular transferase activity, transferring hydroxy groups +namespace: molecular_function +def: "Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule." [GOC:mah] +xref: EC:5.4.4 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0050487 +name: sulfoacetaldehyde acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde." [EC:2.3.3.15, RHEA:24204] +comment: Note that the enzyme sulfoacetaldehyde acetyltransferase also has sulfoacetaldehyde lyase activity (GO:0050312). +synonym: "acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)" EXACT [EC:2.3.3.15] +synonym: "sulphoacetaldehyde acetyltransferase activity" EXACT [] +xref: EC:2.3.3.15 +xref: KEGG_REACTION:R05651 +xref: MetaCyc:RXN-2364 +xref: RHEA:24204 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0050488 +name: ecdysteroid UDP-glucosyltransferase activity +namespace: molecular_function +alt_id: GO:0050489 +def: "Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid." [GOC:ai, PMID:10073711] +synonym: "ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity" RELATED [] +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050490 +name: 1,4-lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid." [EC:3.1.1.25, MetaCyc:14-LACTONASE-RXN] +synonym: "1,4-lactone hydroxyacylhydrolase activity" EXACT [EC:3.1.1.25] +synonym: "gamma-lactonase activity" EXACT [EC:3.1.1.25] +xref: EC:3.1.1.25 +xref: MetaCyc:14-LACTONASE-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050491 +name: sulcatone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone." [EC:1.1.1.260, RHEA:24484] +synonym: "sulcatol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.260] +xref: EC:1.1.1.260 +xref: KEGG_REACTION:R05678 +xref: MetaCyc:1.1.1.260-RXN +xref: RHEA:24484 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050492 +name: glycerol-1-phosphate dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate." [EC:1.1.1.261, MetaCyc:1.1.1.261-RXN] +synonym: "sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.261] +xref: EC:1.1.1.261 +xref: MetaCyc:1.1.1.261-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050493 +name: GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0164] +synonym: "GPI anchor anabolism via N-threonyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor formation via N-threonyl-glycosylphosphatidylinositolethanolamine" EXACT [] +synonym: "GPI anchor synthesis via N-threonyl-glycosylphosphatidylinositolethanolamine" EXACT [] +xref: RESID:AA0164 +is_a: GO:0006506 ! GPI anchor biosynthetic process +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0050494 +name: GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein." [RESID:AA0165] +synonym: "GSI anchor anabolism via N-glycyl-glycosylsphingolipidinositolethanolamine" EXACT [] +synonym: "GSI anchor formation via N-glycyl-glycosylsphingolipidinositolethanolamine" EXACT [] +synonym: "GSI anchor synthesis via N-glycyl-glycosylsphingolipidinositolethanolamine" EXACT [] +xref: RESID:AA0165 +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0042082 ! GSI anchor biosynthetic process + +[Term] +id: GO:0050495 +name: peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine." [RESID:AA0346] +synonym: "peptidyl-glycyl-phosphatidylethanolamine anabolism from peptidyl-glycine" EXACT [] +synonym: "peptidyl-glycyl-phosphatidylethanolamine formation from peptidyl-glycine" EXACT [] +synonym: "peptidyl-glycyl-phosphatidylethanolamine synthesis from peptidyl-glycine" EXACT [] +xref: RESID:AA0346 +is_a: GO:0018201 ! peptidyl-glycine modification + +[Term] +id: GO:0050496 +name: peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine +namespace: biological_process +def: "The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide." [PMID:10411887, RESID:AA0347] +synonym: "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester anabolism from peptidyl-glutamine" EXACT [] +synonym: "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester formation from peptidyl-glutamine" EXACT [] +synonym: "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester synthesis from peptidyl-glutamine" EXACT [] +xref: RESID:AA0340 +is_a: GO:0018199 ! peptidyl-glutamine modification + +[Term] +id: GO:0050497 +name: transferase activity, transferring alkylthio groups +namespace: molecular_function +def: "Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor)." [GOC:ai] +xref: EC:2.8.4 +is_a: GO:0016782 ! transferase activity, transferring sulfur-containing groups + +[Term] +id: GO:0050498 +name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated." [GOC:mah] +xref: EC:1.14.20 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050499 +name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H." [GOC:mah] +xref: EC:1.20.1 +is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors + +[Term] +id: GO:0050500 +name: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate." [EC:2.4.1.211, MetaCyc:2.4.1.211-RXN] +synonym: "beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT [] +synonym: "beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity" EXACT [EC:2.4.1.211] +synonym: "beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity" EXACT [EC:2.4.1.211] +xref: EC:2.4.1.211 +xref: MetaCyc:2.4.1.211-RXN +xref: RHEA:20285 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050501 +name: hyaluronan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP." [EC:2.4.1.212, MetaCyc:2.4.1.212-RXN] +synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212] +synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212] +synonym: "HAS activity" BROAD [EC:2.4.1.212] +synonym: "seHAS" RELATED [EC:2.4.1.212] +synonym: "spHAS" RELATED [EC:2.4.1.212] +xref: EC:2.4.1.212 +xref: MetaCyc:2.4.1.212-RXN +xref: Reactome:R-HSA-2160851 "HAS1,2,3 mediate the polymerisation of HA" +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050502 +name: cis-zeatin O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP." [EC:2.4.1.215, RHEA:20681] +synonym: "cis-zeatin O-b-D-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.215] +synonym: "UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.215] +xref: EC:2.4.1.215 +xref: KEGG_REACTION:R07260 +xref: MetaCyc:RXN-4735 +xref: RHEA:20681 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050503 +name: trehalose 6-phosphate phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate." [EC:2.4.1.216, MetaCyc:2.4.1.216-RXN] +synonym: "trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.216] +xref: EC:2.4.1.216 +xref: MetaCyc:2.4.1.216-RXN +xref: RHEA:20864 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0050504 +name: mannosyl-3-phosphoglycerate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+)." [EC:2.4.1.217, RHEA:13537] +synonym: "GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.217] +synonym: "MPG synthase activity" EXACT [EC:2.4.1.217] +xref: EC:2.4.1.217 +xref: KEGG_REACTION:R05768 +xref: MetaCyc:2.4.1.217-RXN +xref: RHEA:13537 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050505 +name: hydroquinone glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP." [EC:2.4.1.218, RHEA:12560] +synonym: "arbutin synthase activity" EXACT [EC:2.4.1.218] +synonym: "hydroquinone:O-glucosyltransferase activity" EXACT [EC:2.4.1.218] +synonym: "UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.218] +synonym: "UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.218] +xref: EC:2.4.1.218 +xref: KEGG_REACTION:R05769 +xref: MetaCyc:2.4.1.218-RXN +xref: RHEA:12560 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050506 +name: vomilenine glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP." [EC:2.4.1.219, RHEA:19385] +synonym: "UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] +synonym: "UDPG:vomilenine 21-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] +synonym: "UDPG:vomilenine 21beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] +synonym: "vomilenine-glucosyltransferase activity" EXACT [EC:2.4.1.219] +xref: EC:2.4.1.219 +xref: KEGG_REACTION:R05882 +xref: MetaCyc:2.4.1.219-RXN +xref: RHEA:19385 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050507 +name: indoxyl-UDPG glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP." [EC:2.4.1.220, RHEA:12004] +synonym: "indoxyl-UDPG-glucosyltransferase activity" EXACT [EC:2.4.1.220] +synonym: "UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.220] +xref: EC:2.4.1.220 +xref: KEGG_REACTION:R06048 +xref: MetaCyc:2.4.1.220-RXN +xref: RHEA:12004 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050508 +name: glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP." [EC:2.4.1.224, MetaCyc:2.4.1.224-RXN] +synonym: "alpha-N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.224] +synonym: "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity" EXACT [] +synonym: "glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.224] +synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.224] +xref: EC:2.4.1.224 +xref: MetaCyc:2.4.1.224-RXN +xref: Reactome:R-HSA-2022851 "EXT1:EXT2 transfer GlcNAc to the heparan chain" +xref: Reactome:R-HSA-2022919 "EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue" +xref: Reactome:R-HSA-3656254 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain" +xref: Reactome:R-HSA-3656261 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain" +xref: Reactome:R-HSA-9036283 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the terminal GlcA residue" +xref: Reactome:R-HSA-9036290 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to heparan" +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0050509 +name: N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP." [EC:2.4.1.225, MetaCyc:2.4.1.225-RXN] +synonym: "heparan glucuronyltransferase II activity" EXACT [EC:2.4.1.225] +synonym: "N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity" EXACT [] +synonym: "N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity" EXACT [EC:2.4.1.225] +synonym: "UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity" EXACT [EC:2.4.1.225] +xref: EC:2.4.1.225 +xref: MetaCyc:2.4.1.225-RXN +xref: Reactome:R-HSA-2022856 "EXT1:EXT2 transfers GlcNAc to heparan" +xref: Reactome:R-HSA-2076392 "EXT1:EXT2 transfers GlcA to heparan" +xref: Reactome:R-HSA-3656257 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan" +xref: Reactome:R-HSA-3656267 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan" +xref: Reactome:R-HSA-9036285 "Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan" +xref: Reactome:R-HSA-9036289 "Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan" +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0050510 +name: N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP." [EC:2.4.1.226, MetaCyc:2.4.1.226-RXN] +synonym: "alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity" EXACT [EC:2.4.1.226] +synonym: "chondroitin glucuronyltransferase II activity" EXACT [EC:2.4.1.226] +synonym: "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity" EXACT [] +xref: EC:2.4.1.226 +xref: MetaCyc:2.4.1.226-RXN +xref: Reactome:R-HSA-1971491 "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin" +xref: Reactome:R-HSA-3595178 "Defective CHSY1 does not transfer GlcA to chondroitin" +xref: Reactome:R-HSA-9632034 "CHSY1 transfers GlcA to chondroitin" +is_a: GO:0015020 ! glucuronosyltransferase activity + +[Term] +id: GO:0050511 +name: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP." [EC:2.4.1.227, MetaCyc:2.4.1.227-RXN] +comment: Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227. +synonym: "MurG transferase activity" RELATED [EC:2.4.1.227] +synonym: "UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity" EXACT [EC:2.4.1.227] +synonym: "UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity" EXACT [EC:2.4.1.227] +synonym: "undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity" EXACT [EC:2.4.1.227] +synonym: "undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity" EXACT [] +xref: EC:2.4.1.227 +xref: MetaCyc:RXN-8976 +is_a: GO:0008375 ! acetylglucosaminyltransferase activity + +[Term] +id: GO:0050512 +name: lactosylceramide 4-alpha-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.228, MetaCyc:2.4.1.228-RXN] +synonym: "Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.228] +synonym: "Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] +synonym: "globotriaosylceramide/CD77 synthase activity" NARROW [EC:2.4.1.228] +synonym: "histo-blood group P(k) UDP-galactose activity" NARROW [EC:2.4.1.228] +synonym: "histo-blood group Pk UDP-galactose" RELATED [EC:2.4.1.228] +synonym: "lactosylceramide 4-a-galactosyltransferase activity" EXACT [] +synonym: "UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.228] +xref: EC:2.4.1.228 +xref: MetaCyc:2.4.1.228-RXN +xref: RHEA:11924 +is_a: GO:0035250 ! UDP-galactosyltransferase activity + +[Term] +id: GO:0050513 +name: glycoprotein 2-beta-D-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP." [EC:2.4.2.38, RHEA:10612] +synonym: "1,2-beta-xylosyltransferase activity" EXACT [EC:2.4.2.38] +synonym: "beta-1,2-xylosyltransferase activity" EXACT [EC:2.4.2.38] +synonym: "glycoprotein 2-b-D-xylosyltransferase activity" EXACT [] +xref: EC:2.4.2.38 +xref: KEGG_REACTION:R06016 +xref: MetaCyc:2.4.2.38-RXN +xref: RHEA:10612 +is_a: GO:0035252 ! UDP-xylosyltransferase activity + +[Term] +id: GO:0050514 +name: homospermidine synthase (spermidine-specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine." [EC:2.5.1.45, MetaCyc:2.5.1.45-RXN] +synonym: "spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)" EXACT [EC:2.5.1.45] +xref: EC:2.5.1.45 +xref: MetaCyc:2.5.1.45-RXN +xref: RHEA:11236 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0050515 +name: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity +namespace: molecular_function +alt_id: GO:0008698 +def: "Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+)." [EC:2.7.1.148, RHEA:18437] +synonym: "4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity" EXACT [EC:2.7.1.148] +synonym: "4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity" EXACT [] +synonym: "ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity" EXACT [EC:2.7.1.148] +synonym: "CDP-ME kinase activity" EXACT [EC:2.7.1.148] +synonym: "CMK activity" RELATED [EC:2.7.1.148] +xref: EC:2.7.1.148 +xref: KEGG_REACTION:R05634 +xref: MetaCyc:2.7.1.148-RXN +xref: RHEA:18437 +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0050516 +name: obsolete inositol polyphosphate multikinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate." [EC:2.7.1.151, MetaCyc:2.7.1.151-RXN] +comment: This term was made obsolete because this activity is currently defined as catalyzing two sequential reactions based on a gene product. However, "inositol polyphosphate multikinase activity" in some organisms can catalyze additional reactions. In addition, the reactions listed in the definition can be catalyzed independently by other gene products. +synonym: "ArgRIII" RELATED [EC:2.7.1.151] +synonym: "AtIpk2-alpha activity" NARROW [EC:2.7.1.151] +synonym: "AtIpk2-beta activity" NARROW [EC:2.7.1.151] +synonym: "AtIpk2alpha" RELATED [EC:2.7.1.151] +synonym: "AtIpk2beta" RELATED [EC:2.7.1.151] +synonym: "ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.151] +synonym: "inositol polyphosphate 6-/3-/5-kinase activity" EXACT [EC:2.7.1.151] +synonym: "inositol polyphosphate multikinase activity" EXACT [] +synonym: "inositol-polyphosphate multikinase activity" EXACT [] +synonym: "IP3/IP4 6-/3-kinase activity" EXACT [EC:2.7.1.151] +synonym: "IP3/IP4 dual-specificity 6-/3-kinase activity" EXACT [EC:2.7.1.151] +synonym: "IpK2 activity" RELATED [EC:2.7.1.151] +synonym: "IpmK" RELATED [EC:2.7.1.151] +xref: EC:2.7.1.151 +xref: MetaCyc:2.7.1.151-RXN +is_obsolete: true + +[Term] +id: GO:0050517 +name: obsolete inositol hexakisphosphate kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown)." [EC:2.7.4.21, MetaCyc:2.7.4.21-RXN] +comment: Note that this was EC:2.7.1.152. This term was made obsolete because this activity is currently defined as catalyzing two reactions based on a gene product. The reactions listed in the definition can be catalyzed independently by other gene products. +synonym: "ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.4.21] +synonym: "ATP:1D-myo-inositol-hexakisphosphate phosphotransferase activity" EXACT [EC:2.7.4.21] +synonym: "inositol hexakisphosphate kinase activity" EXACT [] +synonym: "inositol-hexakisphosphate kinase activity" EXACT [] +xref: EC:2.7.4.21 +xref: MetaCyc:2.7.1.152-RXN +is_obsolete: true + +[Term] +id: GO:0050518 +name: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity +namespace: molecular_function +alt_id: GO:0008699 +def: "Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate." [EC:2.7.7.60, RHEA:13429] +synonym: "4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity" EXACT [EC:2.7.7.60] +synonym: "4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity" EXACT [] +synonym: "CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity" EXACT [] +synonym: "MCT activity" RELATED [EC:2.7.7.60] +synonym: "MEP cytidylyltransferase activity" EXACT [] +xref: EC:2.7.7.60 +xref: KEGG_REACTION:R05633 +xref: MetaCyc:2.7.7.60-RXN +xref: RHEA:13429 +is_a: GO:0070567 ! cytidylyltransferase activity + +[Term] +id: GO:0050519 +name: holo-citrate lyase synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase." [EC:2.7.7.61, MetaCyc:2.7.7.61-RXN] +synonym: "2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity" EXACT [EC:2.7.7.61] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity" EXACT [EC:2.7.7.61] +synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity" EXACT [EC:2.7.7.61] +synonym: "CitX" RELATED [EC:2.7.7.61] +synonym: "holo-ACP synthase activity" RELATED [EC:2.7.7.61] +xref: EC:2.7.7.61 +xref: MetaCyc:2.7.7.61-RXN +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0050520 +name: phosphatidylcholine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)." [EC:2.7.8.24, RHEA:14597] +synonym: "CDP-diacylglycerol:choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] +synonym: "CDP-diglyceride-choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] +synonym: "CDPdiglyceride-choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] +synonym: "PC synthase activity" EXACT [EC:2.7.8.24] +xref: EC:2.7.8.24 +xref: KEGG_REACTION:R05794 +xref: MetaCyc:2.7.8.24-RXN +xref: RHEA:14597 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0050521 +name: alpha-glucan, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate." [EC:2.7.9.4, MetaCyc:2.7.9.4-RXN] +synonym: "a-glucan, water dikinase activity" EXACT [] +synonym: "alpha-glucan,water dikinase activity" EXACT [EC:2.7.9.4] +synonym: "ATP:alpha-glucan, water phosphotransferase activity" EXACT [EC:2.7.9.4] +synonym: "GWD" RELATED [EC:2.7.9.4] +synonym: "starch-related R1 protein activity" EXACT [EC:2.7.9.4] +xref: EC:2.7.9.4 +xref: MetaCyc:2.7.9.4-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0050522 +name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP." [GOC:ai] +xref: EC:1.20.98 +is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors + +[Term] +id: GO:0050523 +name: obsolete oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors +namespace: molecular_function +def: "OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP." [GOC:ai] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors" EXACT [] +is_obsolete: true +consider: GO:0030613 + +[Term] +id: GO:0050524 +name: coenzyme-B sulfoethylthiotransferase activity +namespace: molecular_function +alt_id: GO:0018552 +def: "Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB." [EC:2.8.4.1, RHEA:12532] +synonym: "2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity" EXACT [EC:2.8.4.1] +synonym: "coenzyme-B sulphoethylthiotransferase activity" EXACT [] +synonym: "methyl coenzyme M reductase activity" EXACT [EC:2.8.4.1] +synonym: "methyl-coenzyme-M reductase activity" EXACT [] +synonym: "methyl-CoM reductase activity" EXACT [EC:2.8.4.1] +xref: EC:2.8.4.1 +xref: KEGG_REACTION:R04541 +xref: MetaCyc:METHYL-COM-HTP-RXN +xref: RHEA:12532 +xref: UM-BBD_reactionID:r0356 +is_a: GO:0050497 ! transferase activity, transferring alkylthio groups + +[Term] +id: GO:0050525 +name: cutinase activity +namespace: molecular_function +def: "Catalysis of the reaction: cutin + H2O = cutin monomers." [EC:3.1.1.74, MetaCyc:3.1.1.74-RXN] +synonym: "cutin hydrolase activity" EXACT [EC:3.1.1.74] +xref: EC:3.1.1.74 +xref: MetaCyc:3.1.1.74-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050526 +name: poly(3-hydroxybutyrate) depolymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5." [EC:3.1.1.75, MetaCyc:3.1.1.75-RXN] +synonym: "PHB depolymerase activity" EXACT [EC:3.1.1.75] +synonym: "poly((R)-hydroxyalkanoic acid) depolymerase activity" BROAD [EC:3.1.1.75] +synonym: "poly(3HB) depolymerase activity" EXACT [EC:3.1.1.75] +synonym: "poly(HA(SCL)) depolymerase activity" EXACT [EC:3.1.1.75] +synonym: "poly(HA) depolymerase activity" RELATED [EC:3.1.1.75] +synonym: "poly(HASCL) depolymerase activity" EXACT [EC:3.1.1.75] +synonym: "poly[(R)-3-hydroxybutyrate] hydrolase activity" EXACT [EC:3.1.1.75] +synonym: "poly[(R)-hydroxyalkanoic acid] depolymerase" BROAD [EC:3.1.1.75] +xref: EC:3.1.1.75 +xref: MetaCyc:3.1.1.75-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050527 +name: poly(3-hydroxyoctanoate) depolymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5." [EC:3.1.1.76, MetaCyc:3.1.1.76-RXN] +synonym: "PHA depolymerase activity" BROAD [EC:3.1.1.76] +synonym: "PHO depolymerase activity" EXACT [EC:3.1.1.76] +synonym: "poly((R)-3-hydroxyoctanoate) hydrolase activity" EXACT [EC:3.1.1.76] +synonym: "poly((R)-hydroxyalkanoic acid) depolymerase activity" BROAD [EC:3.1.1.76] +synonym: "poly(3HO) depolymerase activity" EXACT [EC:3.1.1.76] +synonym: "poly(HA(MCL)) depolymerase activity" EXACT [EC:3.1.1.76] +synonym: "poly(HA) depolymerase activity" BROAD [EC:3.1.1.76] +synonym: "poly(HAMCL) depolymerase activity" EXACT [EC:3.1.1.76] +synonym: "poly[(R)-3-hydroxyoctanoate] hydrolase activity" EXACT [EC:3.1.1.76] +synonym: "poly[(R)-hydroxyalkanoic acid] depolymerase" BROAD [EC:3.1.1.76] +synonym: "poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity" EXACT [EC:3.1.1.76] +xref: EC:3.1.1.76 +xref: MetaCyc:3.1.1.76-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050528 +name: acyloxyacyl hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid." [EC:3.1.1.77, MetaCyc:3.1.1.77-RXN] +xref: EC:3.1.1.77 +xref: MetaCyc:3.1.1.77-RXN +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050529 +name: polyneuridine-aldehyde esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol." [EC:3.1.1.78, RHEA:17501] +synonym: "PNAE activity" EXACT [EC:3.1.1.78] +synonym: "polyneuridine aldehyde esterase activity" EXACT [EC:3.1.1.78] +synonym: "polyneuridine aldehyde hydrolase (decarboxylating)" EXACT [EC:3.1.1.78] +xref: EC:3.1.1.78 +xref: KEGG_REACTION:R05825 +xref: MetaCyc:3.1.1.78-RXN +xref: RHEA:17501 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0050530 +name: glucosylglycerol 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate." [EC:3.1.3.69, RHEA:22652] +synonym: "2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.69] +synonym: "salt tolerance protein A" RELATED [EC:3.1.3.69] +synonym: "StpA" RELATED [EC:3.1.3.69] +xref: EC:3.1.3.69 +xref: KEGG_REACTION:R05791 +xref: MetaCyc:3.1.3.69-RXN +xref: RHEA:22652 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050531 +name: mannosyl-3-phosphoglycerate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate." [EC:3.1.3.70, RHEA:19309] +synonym: "alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity" EXACT [EC:3.1.3.70] +xref: EC:3.1.3.70 +xref: KEGG_REACTION:R05790 +xref: MetaCyc:3.1.3.70-RXN +xref: RHEA:19309 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050532 +name: 2-phosphosulfolactate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate." [EC:3.1.3.71, RHEA:23416] +synonym: "(2R)-phosphosulfolactate phosphohydrolase activity" EXACT [EC:3.1.3.71] +synonym: "(R)-2-phospho-3-sulfolactate phosphohydrolase activity" EXACT [EC:3.1.3.71] +synonym: "2-phosphosulpholactate phosphatase activity" EXACT [] +synonym: "ComB phosphatase activity" RELATED [EC:3.1.3.71] +xref: EC:3.1.3.71 +xref: KEGG_REACTION:R05789 +xref: MetaCyc:R229-RXN +xref: RHEA:23416 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050533 +name: 5-phytase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate." [EC:3.1.3.72, MetaCyc:3.1.3.72-RXN] +synonym: "myo-inositol-hexakisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.72] +xref: EC:3.1.3.72 +xref: MetaCyc:3.1.3.72-RXN +xref: RHEA:13001 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0050534 +name: 3-deoxyoctulosonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide." [EC:3.2.1.144, MetaCyc:3.2.1.144-RXN] +synonym: "3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity" EXACT [EC:3.2.1.144] +synonym: "alpha-Kdo-ase activity" EXACT [EC:3.2.1.144] +xref: EC:3.2.1.144 +xref: MetaCyc:3.2.1.144-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0050535 +name: beta-primeverosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol." [EC:3.2.1.149, MetaCyc:3.2.1.149-RXN] +synonym: "6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity" EXACT [EC:3.2.1.149] +synonym: "b-primeverosidase activity" EXACT [] +xref: EC:3.2.1.149 +xref: MetaCyc:3.2.1.149-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0050536 +name: (S)-N-acetyl-1-phenylethylamine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine." [EC:3.5.1.85, RHEA:23952] +synonym: "(S)-N-acetyl-1-phenylethylamine amidohydrolase activity" EXACT [EC:3.5.1.85] +synonym: "(S)-N-acetylphenylethylamine:H2O hydrolase activity" EXACT [EC:3.5.1.85] +xref: EC:3.5.1.85 +xref: KEGG_REACTION:R07301 +xref: MetaCyc:3.5.1.85-RXN +xref: RHEA:23952 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050537 +name: mandelamide amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+)." [EC:3.5.1.86, RHEA:22876] +synonym: "mandelamide hydrolase activity" EXACT [EC:3.5.1.86] +synonym: "Pseudomonas mandelamide hydrolase activity" EXACT [EC:3.5.1.86] +xref: EC:3.5.1.86 +xref: KEGG_REACTION:R05783 +xref: MetaCyc:3.5.1.86-RXN +xref: RHEA:22876 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050538 +name: N-carbamoyl-L-amino-acid hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate." [EC:3.5.1.87, MetaCyc:3.5.1.87-RXN] +synonym: "L-carbamoylase activity" EXACT [EC:3.5.1.87] +synonym: "N-carbamoyl-L-amino acid amidohydrolase activity" EXACT [EC:3.5.1.87] +xref: EC:3.5.1.87 +xref: MetaCyc:3.5.1.87-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050539 +name: maleimide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate." [EC:3.5.2.16, RHEA:24476] +synonym: "cyclic imide hydrolase activity" EXACT [EC:3.5.2.16] +synonym: "cyclic-imide amidohydrolase (decyclicizing)" EXACT [EC:3.5.2.16] +synonym: "cyclic-imide amidohydrolase (decyclizing)" EXACT [EC:3.5.2.16] +synonym: "imidase activity" BROAD [EC:3.5.2.16] +xref: EC:3.5.2.16 +xref: KEGG_REACTION:R05781 +xref: MetaCyc:3.5.2.16-RXN +xref: RHEA:24476 +is_a: GO:0016812 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + +[Term] +id: GO:0050540 +name: 2-aminomuconate deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+)." [EC:3.5.99.5, RHEA:20996] +synonym: "2-aminomuconate aminohydrolase activity" EXACT [EC:3.5.99.5] +xref: EC:3.5.99.5 +xref: KEGG_REACTION:R03887 +xref: MetaCyc:3.5.99.5-RXN +xref: RHEA:20996 +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +is_a: GO:0019239 ! deaminase activity + +[Term] +id: GO:0050541 +name: beta,beta-carotene-9',10'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone." [PMID:11278918] +synonym: "b,b-carotene-9',10'-dioxygenase activity" EXACT [] +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0050542 +name: icosanoid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids." [ISBN:0198506732] +synonym: "eicosanoid binding" EXACT [] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:1901567 ! fatty acid derivative binding + +[Term] +id: GO:0050543 +name: icosatetraenoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule." [ISBN:0198506732] +synonym: "eicosatetraenoic acid binding" EXACT [] +is_a: GO:0036041 ! long-chain fatty acid binding + +[Term] +id: GO:0050544 +name: arachidonic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer." [GOC:ai] +synonym: "arachidonate binding" EXACT [] +is_a: GO:0050542 ! icosanoid binding +is_a: GO:0050543 ! icosatetraenoic acid binding + +[Term] +id: GO:0050545 +name: sulfopyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde." [EC:4.1.1.79, RHEA:20948] +synonym: "sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)" EXACT [EC:4.1.1.79] +synonym: "sulfopyruvate carboxy-lyase activity" EXACT [EC:4.1.1.79] +synonym: "sulphopyruvate decarboxylase activity" EXACT [] +xref: EC:4.1.1.79 +xref: KEGG_REACTION:R05774 +xref: MetaCyc:R231-RXN +xref: RHEA:20948 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050546 +name: 4-hydroxyphenylpyruvate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2)." [EC:4.1.1.80, RHEA:18697] +synonym: "4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming)" EXACT [EC:4.1.1.80] +synonym: "4-hydroxyphenylpyruvate carboxy-lyase activity" EXACT [EC:4.1.1.80] +xref: EC:4.1.1.80 +xref: KEGG_REACTION:R03341 +xref: MetaCyc:4.1.1.80-RXN +xref: RHEA:18697 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050547 +name: vanillin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin." [EC:4.1.2.41, RHEA:18725] +synonym: "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.2.41] +synonym: "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming)" EXACT [EC:4.1.2.41] +xref: EC:4.1.2.41 +xref: KEGG_REACTION:R05773 +xref: MetaCyc:4.1.2.41-RXN +xref: RHEA:18725 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0050548 +name: trans-feruloyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA." [EC:4.2.1.101, MetaCyc:4.2.1.101-RXN] +synonym: "4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)" EXACT [EC:4.2.1.101] +synonym: "trans-feruloyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.101] +xref: EC:4.2.1.101 +xref: MetaCyc:4.2.1.101-RXN +xref: RHEA:14517 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050549 +name: cyclohexyl-isocyanide hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O." [EC:4.2.1.103, RHEA:18197] +synonym: "isonitrile hydratase activity" EXACT [EC:4.2.1.103] +synonym: "N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)" EXACT [EC:4.2.1.103] +synonym: "N-cyclohexylformamide hydro-lyase activity" EXACT [EC:4.2.1.103] +xref: EC:4.2.1.103 +xref: KEGG_REACTION:R05771 +xref: MetaCyc:4.2.1.103-RXN +xref: RHEA:18197 +xref: UM-BBD_reactionID:r1029 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0050550 +name: pinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate." [EC:4.2.3.14, MetaCyc:4.2.3.14-RXN] +synonym: "(-)-(1S,5S)-pinene synthase activity" EXACT [EC:4.2.3.14] +synonym: "beta-geraniolene synthase activity" EXACT [EC:4.2.3.14] +synonym: "geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming)" EXACT [EC:4.2.3.14] +synonym: "geranyldiphosphate diphosphate lyase (pinene forming)" EXACT [EC:4.2.3.14] +xref: EC:4.2.3.14 +xref: MetaCyc:4.2.3.14-RXN +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0050551 +name: myrcene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene." [EC:4.2.3.15, RHEA:16965] +synonym: "geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity" EXACT [] +xref: EC:4.2.3.15 +xref: KEGG_REACTION:R02009 +xref: MetaCyc:RXN-5110 +xref: RHEA:16965 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0050552 +name: (4S)-limonene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate." [EC:4.2.3.16, MetaCyc:4.2.3.16-RXN] +synonym: "(-)-(4S)-limonene synthase activity" EXACT [] +synonym: "4S-(-)-limonene synthase activity" EXACT [EC:4.2.3.16] +synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]" RELATED [EC:4.2.3.16] +synonym: "geranyldiphosphate diphosphate lyase (limonene forming)" EXACT [EC:4.2.3.16] +synonym: "geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]" RELATED [EC:4.2.3.16] +xref: EC:4.2.3.16 +xref: MetaCyc:4.2.3.16-RXN +xref: RHEA:12869 +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0050553 +name: taxadiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene." [EC:4.2.3.17, RHEA:20912] +synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)" EXACT [EC:4.2.3.17] +synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)" EXACT [EC:4.2.3.17] +synonym: "taxa-4(5),11(12)-diene synthase activity" EXACT [EC:4.2.3.17] +xref: EC:4.2.3.17 +xref: KEGG_REACTION:R06305 +xref: MetaCyc:4.2.3.17-RXN +xref: RHEA:20912 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0050554 +name: abietadiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate." [EC:4.2.3.18, RHEA:13873] +synonym: "(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)" EXACT [EC:4.2.3.18] +synonym: "abietadiene cyclase activity" EXACT [EC:4.2.3.18] +synonym: "copalyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.18] +xref: EC:4.2.3.18 +xref: KEGG_REACTION:R06301 +xref: MetaCyc:4.2.3.18-RXN +xref: RHEA:13873 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0050555 +name: 2-hydroxypropyl-CoM lyase activity +namespace: molecular_function +def: "Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane." [EC:4.2.99.19, MetaCyc:4.2.99.19-RXN] +synonym: "(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] +synonym: "(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] +synonym: "2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] +synonym: "coenzyme M-epoxyalkane ligase activity" EXACT [EC:4.4.1.23] +synonym: "EaCoMT activity" EXACT [EC:4.4.1.23] +synonym: "epoxyalkane:2-mercaptoethanesulfonate transferase activity" EXACT [EC:4.4.1.23] +synonym: "epoxyalkane:coenzyme M transferase activity" EXACT [EC:4.4.1.23] +synonym: "epoxyalkane:CoM transferase activity" EXACT [EC:4.4.1.23] +synonym: "epoxyalkyl:CoM transferase activity" EXACT [EC:4.4.1.23] +synonym: "epoxypropane:coenzyme M transferase activity" EXACT [EC:4.4.1.23] +synonym: "epoxypropyl:CoM transferase activity" EXACT [EC:4.4.1.23] +xref: EC:4.4.1.23 +xref: MetaCyc:4.2.99.19-RXN +xref: UM-BBD_enzymeID:e0538 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0050556 +name: deacetylisoipecoside synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin." [EC:4.3.3.3, RHEA:21756] +synonym: "deacetylisoipecoside dopamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.3] +synonym: "deacetylisoipecoside dopamine-lyase activity" EXACT [EC:4.3.3.3] +xref: EC:4.3.3.3 +xref: KEGG_REACTION:R05750 +xref: MetaCyc:4.3.3.3-RXN +xref: RHEA:21756 +is_a: GO:0016843 ! amine-lyase activity + +[Term] +id: GO:0050557 +name: deacetylipecoside synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin." [EC:4.3.3.4, RHEA:12296] +synonym: "deacetylipecoside dopamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.4] +synonym: "deacetylipecoside dopamine-lyase activity" EXACT [EC:4.3.3.4] +xref: EC:4.3.3.4 +xref: KEGG_REACTION:R05749 +xref: MetaCyc:4.3.3.4-RXN +xref: RHEA:12296 +is_a: GO:0016843 ! amine-lyase activity + +[Term] +id: GO:0050558 +name: maltose epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-maltose = beta-maltose." [EC:5.1.3.21, RHEA:21228] +synonym: "maltose 1-epimerase activity" EXACT [EC:5.1.3.21] +xref: EC:5.1.3.21 +xref: KEGG_REACTION:R07319 +xref: MetaCyc:5.1.3.21-RXN +xref: RHEA:21228 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0050559 +name: copalyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate." [EC:5.5.1.12, RHEA:24316] +synonym: "(+)-copalyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.12] +synonym: "diterpene cyclase activity" BROAD [] +xref: EC:5.5.1.12 +xref: KEGG_REACTION:R06298 +xref: MetaCyc:RXN-4861 +xref: RHEA:24316 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0050560 +name: aspartate-tRNA(Asn) ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP." [EC:6.1.1.23, MetaCyc:6.1.1.23-RXN] +synonym: "aspartate-tRNAAsn ligase activity" EXACT [] +synonym: "L-aspartate:tRNAAsx ligase (AMP-forming)" EXACT [EC:6.1.1.23] +synonym: "nondiscriminating aspartyl-tRNA synthetase activity" RELATED [EC:6.1.1.23] +xref: EC:6.1.1.23 +xref: MetaCyc:6.1.1.23-RXN +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0050561 +name: glutamate-tRNA(Gln) ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP." [EC:6.1.1.24, MetaCyc:6.1.1.24-RXN] +synonym: "glutamate-tRNAGln ligase activity" EXACT [] +synonym: "L-glutamate:tRNAGlx ligase (AMP-forming)" EXACT [EC:6.1.1.24] +synonym: "nondiscriminating glutamyl-tRNA synthetase activity" RELATED [EC:6.1.1.24] +xref: EC:6.1.1.24 +xref: MetaCyc:6.1.1.24-RXN +xref: RHEA:18397 +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0050562 +name: lysine-tRNA(Pyl) ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP." [MetaCyc:6.1.1.25-RXN] +synonym: "L-lysine:tRNAPyl ligase (AMP-forming)" EXACT [] +synonym: "lysine-tRNAPyl ligase activity" EXACT [] +xref: MetaCyc:6.1.1.25-RXN +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0050563 +name: trans-feruloyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ferulic acid + CoASH + ATP = trans-feruloyl-CoA + products of ATP breakdown." [EC:6.2.1.34, MetaCyc:6.2.1.34-RXN] +synonym: "trans-ferulate:CoASH ligase (ATP-hydrolysing)" EXACT [EC:6.2.1.34] +synonym: "trans-feruloyl-CoA synthetase activity" EXACT [EC:6.2.1.34] +xref: EC:6.2.1.34 +xref: MetaCyc:6.2.1.34-RXN +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0050564 +name: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+)." [EC:6.3.2.26, RHEA:23196] +synonym: "ACV synthetase activity" BROAD [EC:6.3.2.26] +synonym: "L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)" EXACT [EC:6.3.2.26] +synonym: "L-alpha-aminoadipyl-cysteinyl-valine synthetase activity" EXACT [EC:6.3.2.26] +synonym: "L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity" EXACT [EC:6.3.2.26] +xref: EC:6.3.2.26 +xref: KEGG_REACTION:R04870 +xref: MetaCyc:6.3.2.26-RXN +xref: RHEA:23196 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0050565 +name: aerobactin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate." [RHEA:11760] +synonym: "citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)" EXACT [] +synonym: "citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)" EXACT [] +xref: KEGG_REACTION:R04357 +xref: MetaCyc:6.3.2.27-RXN +xref: RHEA:11760 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0050566 +name: asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP." [EC:6.3.5.6, MetaCyc:6.3.5.6-RXN] +synonym: "Asp-AdT activity" EXACT [EC:6.3.5.6] +synonym: "Asp-tRNA(Asn) amidotransferase activity" EXACT [EC:6.3.5.6] +synonym: "Asp-tRNAAsn amidotransferase activity" EXACT [EC:6.3.5.6] +synonym: "Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.6] +synonym: "asparaginyl-tRNA synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.6] +synonym: "aspartyl-tRNA(Asn) amidotransferase activity" EXACT [EC:6.3.5.6] +synonym: "aspartyl-tRNAAsn amidotransferase activity" EXACT [EC:6.3.5.6] +synonym: "aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.6] +xref: EC:6.3.5.6 +xref: MetaCyc:6.3.5.6-RXN +xref: RHEA:14513 +xref: Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing) +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0050567 +name: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +alt_id: GO:0008264 +alt_id: GO:0017068 +def: "Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP." [EC:6.3.5.7, MetaCyc:6.3.5.7-RXN] +synonym: "Glu-AdT activity" EXACT [EC:6.3.5.-] +synonym: "Glu-tRNA(Gln) amidotransferase activity" EXACT [EC:6.3.5.-] +synonym: "Glu-tRNAGln amidotransferase activity" EXACT [EC:6.3.5.7] +synonym: "Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.7] +synonym: "glutaminyl-tRNA synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.7] +synonym: "glutamyl-tRNA(Gln) amidotransferase activity" EXACT [EC:6.3.5.-] +synonym: "glutamyl-tRNAGln amidotransferase activity" EXACT [EC:6.3.5.7] +synonym: "glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.7] +xref: EC:6.3.5.7 +xref: MetaCyc:6.3.5.7-RXN +xref: RHEA:17521 +xref: Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing) +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0050568 +name: protein-glutamine glutaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3." [EC:3.5.1.44, MetaCyc:CHEBDEAMID-RXN] +synonym: "destabilase activity" EXACT [EC:3.5.1.44] +synonym: "glutaminyl-peptide glutaminase activity" EXACT [EC:3.5.1.44] +synonym: "glutaminylpeptide glutaminase activity" EXACT [EC:3.5.1.44] +synonym: "peptidoglutaminase II activity" RELATED [EC:3.5.1.44] +synonym: "peptidylglutaminase II" RELATED [EC:3.5.1.44] +synonym: "protein-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.44] +xref: EC:3.5.1.44 +xref: MetaCyc:CHEBDEAMID-RXN +xref: RHEA:16441 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0050569 +name: glycolaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH." [EC:1.2.1.21, RHEA:20001] +synonym: "glycol aldehyde dehydrogenase activity" EXACT [EC:1.2.1.21] +synonym: "glycolaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.21] +xref: EC:1.2.1.21 +xref: KEGG_REACTION:R01333 +xref: MetaCyc:GLYCOLALD-DEHYDROG-RXN +xref: RHEA:20001 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity + +[Term] +id: GO:0050570 +name: 4-hydroxythreonine-4-phosphate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+." [EC:1.1.1.262, RHEA:32275] +synonym: "4-(phosphohydroxy)-L-threonine dehydrogenase activity" EXACT [EC:1.1.1.262] +synonym: "4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.262] +synonym: "L-threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] +synonym: "NAD(+)-dependent threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] +synonym: "NAD+-dependent threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] +synonym: "PdxA" RELATED [EC:1.1.1.262] +xref: EC:1.1.1.262 +xref: MetaCyc:1.1.1.262-RXN +xref: RHEA:32275 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050571 +name: 1,5-anhydro-D-fructose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH." [EC:1.1.1.263, RHEA:20665] +synonym: "1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.263] +synonym: "AF reductase activity" EXACT [EC:1.1.1.263] +xref: EC:1.1.1.263 +xref: KEGG_REACTION:R05682 +xref: MetaCyc:1.1.1.263-RXN +xref: RHEA:20665 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050572 +name: L-idonate 5-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+." [EC:1.1.1.264, MetaCyc:1.1.1.264-RXN] +synonym: "L-idonate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.264] +xref: EC:1.1.1.264 +xref: MetaCyc:1.1.1.264-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050573 +name: dTDP-4-dehydro-6-deoxyglucose reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH." [EC:1.1.1.266, RHEA:21903] +synonym: "dTDP-4-keto-6-deoxyglucose reductase activity" EXACT [EC:1.1.1.266] +synonym: "dTDP-D-fucose:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.266] +xref: EC:1.1.1.266 +xref: KEGG_REACTION:R05687 +xref: MetaCyc:1.1.1.266-RXN +xref: RHEA:21903 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050574 +name: 2-(R)-hydroxypropyl-CoM dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH." [EC:1.1.1.268, RHEA:13249] +synonym: "2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity" EXACT [EC:1.1.1.268] +synonym: "2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.268] +xref: EC:1.1.1.268 +xref: KEGG_REACTION:R05689 +xref: MetaCyc:1.1.1.268-RXN +xref: RHEA:13249 +xref: UM-BBD_reactionID:r0852 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050575 +name: 2-(S)-hydroxypropyl-CoM dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH." [EC:1.1.1.269, RHEA:21052] +synonym: "2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity" EXACT [EC:1.1.1.269] +synonym: "2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.269] +xref: EC:1.1.1.269 +xref: KEGG_REACTION:R05690 +xref: MetaCyc:1.1.1.269-RXN +xref: RHEA:21052 +xref: UM-BBD_reactionID:r0853 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050577 +name: GDP-L-fucose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+." [EC:1.1.1.271, MetaCyc:1.1.1.271-RXN] +synonym: "GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity" EXACT [EC:1.1.1.271] +synonym: "GDP-fucose synthetase activity" EXACT [EC:1.1.1.271] +synonym: "GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)" EXACT [EC:1.1.1.271] +xref: EC:1.1.1.271 +xref: MetaCyc:1.1.1.271-RXN +xref: Reactome:R-HSA-6787642 "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc" +xref: RHEA:18885 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +relationship: part_of GO:0042350 ! GDP-L-fucose biosynthetic process + +[Term] +id: GO:0050578 +name: (R)-2-hydroxyacid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+." [EC:1.1.1.272, MetaCyc:1.1.1.272-RXN] +synonym: "(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.272] +synonym: "(R)-sulfolactate:NAD(P)(+) oxidoreductase activity" EXACT [EC:1.1.1.272] +synonym: "(R)-sulfolactate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.272] +synonym: "L-sulfolactate dehydrogenase activity" EXACT [EC:1.1.1.272] +xref: EC:1.1.1.272 +xref: MetaCyc:1.1.1.272-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050579 +name: vellosimine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine." [EC:1.1.1.273, RHEA:20029] +synonym: "10-deoxysarpagine:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.273] +xref: EC:1.1.1.273 +xref: KEGG_REACTION:R05827 +xref: MetaCyc:1.1.1.273-RXN +xref: RHEA:20029 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050580 +name: 2,5-didehydrogluconate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+." [EC:1.1.1.274, MetaCyc:1.1.1.274-RXN] +synonym: "2,5-diketo-D-gluconate reductase activity" EXACT [EC:1.1.1.274] +synonym: "2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.274] +synonym: "YqhE reductase" RELATED [EC:1.1.1.274] +xref: EC:1.1.1.274 +xref: MetaCyc:1.1.1.274-RXN +xref: RHEA:23828 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050581 +name: D-mannitol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: mannitol + O2 = mannose + H2O2." [EC:1.1.3.40, MetaCyc:1.1.3.40-RXN] +synonym: "D-arabinitol oxidase activity" RELATED [EC:1.1.3.40] +synonym: "D-arabitol oxidase activity" EXACT [EC:1.1.3.40] +synonym: "mannitol oxidase activity" EXACT [EC:1.1.3.40] +synonym: "mannitol:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.1.3.40] +xref: EC:1.1.3.40 +xref: MetaCyc:1.1.3.40-RXN +xref: RHEA:18513 +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050582 +name: xylitol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: xylitol + O2 = xylose + H2O2." [EC:1.1.3.41, MetaCyc:1.1.3.41-RXN] +synonym: "xylitol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.41] +xref: EC:1.1.3.41 +xref: MetaCyc:1.1.3.41-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0050583 +name: hydrogen dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + H2 = NADPH + H+." [EC:1.12.1.3, MetaCyc:1.12.1.3-RXN] +synonym: "hydrogen:NADP+ oxidoreductase activity" EXACT [EC:1.12.1.3] +synonym: "NADP-linked hydrogenase activity" RELATED [EC:1.12.1.3] +synonym: "NADP-reducing hydrogenase activity" RELATED [EC:1.12.1.3] +xref: EC:1.12.1.3 +xref: MetaCyc:1.12.1.3-RXN +xref: RHEA:18637 +is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor + +[Term] +id: GO:0050584 +name: linoleate 11-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate." [EC:1.13.11.45, RHEA:18993] +synonym: "linoleate dioxygenase activity" EXACT [EC:1.13.11.45] +synonym: "linoleate:oxygen 11S-oxidoreductase activity" EXACT [EC:1.13.11.45] +synonym: "manganese lipoxygenase activity" EXACT [EC:1.13.11.45] +xref: EC:1.13.11.45 +xref: KEGG_REACTION:R05718 +xref: MetaCyc:1.13.11.45-RXN +xref: RHEA:18993 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050585 +name: 4-hydroxymandelate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2." [EC:1.13.11.46, MetaCyc:1.13.11.46-RXN] +synonym: "4-hydroxyphenylpyruvate dioxygenase II activity" NARROW [EC:1.13.11.46] +synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)" BROAD [EC:1.13.11.46] +xref: EC:1.13.11.46 +xref: MetaCyc:1.13.11.46-RXN +xref: RHEA:21376 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050586 +name: 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO." [EC:1.13.11.48, RHEA:21572] +synonym: "(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity" EXACT [EC:1.13.11.48] +synonym: "1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity" EXACT [] +synonym: "1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity" EXACT [] +synonym: "3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)" EXACT [EC:1.13.11.48] +synonym: "3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity" EXACT [] +xref: EC:1.13.11.48 +xref: KEGG_REACTION:R05720 +xref: MetaCyc:1.13.11.48-RXN +xref: RHEA:21572 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050587 +name: chlorite O2-lyase activity +namespace: molecular_function +alt_id: GO:0030065 +def: "Catalysis of the reaction: chloride + O(2) = chlorite." [EC:1.13.11.49, RHEA:21404] +synonym: "chloride:oxygen oxidoreductase activity" EXACT [EC:1.13.11.49] +synonym: "chlorite dismutase activity" EXACT [EC:1.13.11.49] +xref: EC:1.13.11.49 +xref: KEGG_REACTION:R05721 +xref: MetaCyc:1.13.11.49-RXN +xref: RHEA:21404 +xref: UM-BBD_reactionID:r0982 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0050588 +name: apo-beta-carotenoid-14',13'-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal." [EC:1.13.11.67, RHEA:26023] +synonym: "8'-apo-beta-carotenol:O2 oxidoreductase activity" EXACT [EC:1.13.11.67] +synonym: "apo-b-carotenoid-14',13'-dioxygenase activity" EXACT [] +xref: EC:1.13.11.67 +xref: KEGG_REACTION:R08889 +xref: MetaCyc:1.13.12.12-RXN +xref: RHEA:26023 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0050589 +name: leucocyanidin oxygenase activity +namespace: molecular_function +alt_id: GO:0045432 +def: "Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O." [EC:1.14.20.4, MetaCyc:1.14.11.19-RXN] +synonym: "anthocyanidin synthase activity" RELATED [EC:1.14.20.4] +synonym: "leucoanthocyanidin dioxygenase activity" EXACT [EC:1.14.20.4] +synonym: "leucoanthocyanidin hydroxylase" RELATED [EC:1.14.20.4] +synonym: "leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.20.4] +xref: EC:1.14.20.4 +xref: MetaCyc:RXN-602 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0050590 +name: desacetoxyvindoline 4-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2." [EC:1.14.11.20, MetaCyc:1.14.11.20-RXN] +synonym: "D17H activity" RELATED [EC:1.14.11.20] +synonym: "deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)" EXACT [EC:1.14.11.20] +synonym: "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity" EXACT [EC:1.14.11.20] +synonym: "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)" EXACT [EC:1.14.11.20] +synonym: "desacetoxyvindoline-4-hydroxylase activity" EXACT [EC:1.14.11.20] +synonym: "desacetyoxyvindoline-17-hydroxylase activity" EXACT [EC:1.14.11.20] +xref: EC:1.14.11.20 +xref: KEGG_REACTION:R05857 +xref: MetaCyc:1.14.11.20-RXN +xref: RHEA:18973 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0050591 +name: quinine 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+)." [EC:1.14.14.55, RHEA:20149] +synonym: "nifedipine oxidase activity" EXACT [EC:1.14.14.55] +synonym: "quinine 3-hydroxylase activity" EXACT [] +synonym: "quinine,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.14.55] +xref: EC:1.14.14.55 +xref: KEGG_REACTION:R05727 +xref: MetaCyc:1.14.13.67-RXN +xref: RHEA:20149 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050592 +name: 4-hydroxyphenylacetaldehyde oxime monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+)." [EC:1.14.14.37, RHEA:18401] +synonym: "(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.14.37] +synonym: "4-hydroxybenzeneacetaldehyde oxime monooxygenase activity" EXACT [EC:1.14.14.37] +synonym: "4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.14.37] +synonym: "CYP71E1 activity" NARROW [EC:1.14.14.37] +synonym: "cytochrome P450-II-dependent monooxygenase activity" NARROW [EC:1.14.14.37] +synonym: "cytochrome P450II-dependent monooxygenase activity" EXACT [EC:1.14.14.37] +synonym: "NADPH-cytochrome P450 reductase (CYP71E1)" EXACT [EC:1.14.14.37] +xref: EC:1.14.14.37 +xref: KEGG_REACTION:R05728 +xref: MetaCyc:1.14.13.68-RXN +xref: RHEA:18401 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050593 +name: N-methylcoclaurine 3'-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+)." [EC:1.14.14.102, RHEA:16649] +synonym: "(S)-N-methylcoclaurine 3'-hydroxylase activity" EXACT [EC:1.14.14.102] +synonym: "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.14.102] +synonym: "cytochrome P450 80B1 activity" EXACT [EC:1.14.14.102] +synonym: "N-methylcoclaurine 3'-hydroxylase activity" EXACT [] +xref: EC:1.14.14.102 +xref: KEGG_REACTION:R05732 +xref: MetaCyc:1.14.13.71-RXN +xref: RHEA:16649 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050594 +name: tabersonine 16-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+)." [EC:1.14.14.103, RHEA:14133] +synonym: "tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)" EXACT [EC:1.14.14.103] +xref: EC:1.14.14.103 +xref: KEGG_REACTION:R05855 +xref: MetaCyc:1.14.13.73-RXN +xref: RHEA:14133 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050595 +name: 7-deoxyloganin 7-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O." [EC:1.14.13.74, MetaCyc:1.14.13.74-RXN] +synonym: "7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.13.74] +xref: EC:1.14.13.74 +xref: MetaCyc:1.14.13.74-RXN +xref: RHEA:11452 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050596 +name: vinorine hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine." [EC:1.14.14.104, RHEA:17257] +synonym: "vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)" EXACT [EC:1.14.14.104] +xref: EC:1.14.14.104 +xref: KEGG_REACTION:R05877 +xref: MetaCyc:1.14.13.75-RXN +xref: RHEA:17257 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050597 +name: taxane 10-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+)." [EC:1.14.14.105, RHEA:15241] +synonym: "5-alpha-taxadienol-10-beta-hydroxylase activity" EXACT [EC:1.14.14.105] +synonym: "taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)" EXACT [EC:1.14.14.105] +synonym: "taxane 10b-hydroxylase activity" EXACT [] +synonym: "taxane 10beta-hydroxylase activity" EXACT [EC:1.14.14.105] +xref: EC:1.14.14.105 +xref: KEGG_REACTION:R06309 +xref: MetaCyc:1.14.13.76-RXN +xref: RHEA:15241 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050598 +name: taxane 13-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol." [EC:1.14.14.106, RHEA:18949] +synonym: "taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)" EXACT [EC:1.14.14.106] +synonym: "taxane 13a-hydroxylase activity" EXACT [] +synonym: "taxane 13alpha-hydroxylase activity" EXACT [EC:1.14.14.106] +xref: EC:1.14.14.106 +xref: KEGG_REACTION:R06308 +xref: MetaCyc:1.14.13.77-RXN +xref: RHEA:18949 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0050599 +name: deacetoxycephalosporin-C synthase activity +namespace: molecular_function +alt_id: GO:0045441 +def: "Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate." [EC:1.14.20.1, RHEA:20748] +synonym: "DAOC synthase activity" EXACT [EC:1.14.20.1] +synonym: "DAOCS activity" EXACT [EC:1.14.20.1] +synonym: "deacetoxycephalosporin C synthetase activity" EXACT [] +synonym: "expandase activity" EXACT [] +synonym: "penicillin N expandase activity" RELATED [EC:1.14.20.1] +synonym: "penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)" EXACT [EC:1.14.20.1] +xref: EC:1.14.20.1 +xref: KEGG_REACTION:R05301 +xref: MetaCyc:1.14.20.1-RXN +xref: RHEA:20748 +is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated + +[Term] +id: GO:0050600 +name: myristoyl-CoA 11-(E) desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O." [EC:1.14.19.24, MetaCyc:1.14.99.31-RXN] +synonym: "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating]" RELATED [EC:1.14.19.24] +synonym: "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]" RELATED [EC:1.14.99.31] +xref: EC:1.14.19.24 +xref: MetaCyc:1.14.99.31-RXN +xref: RHEA:46396 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050601 +name: myristoyl-CoA 11-(Z) desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O." [EC:1.14.19.5, MetaCyc:1.14.99.32-RXN] +synonym: "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]" RELATED [EC:1.14.19.5] +synonym: "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]" RELATED [EC:1.14.19.5] +xref: EC:1.14.19.5 +xref: MetaCyc:1.14.99.32-RXN +xref: RHEA:25852 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050602 +name: monoprenyl isoflavone epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives." [EC:1.14.99.34, MetaCyc:1.14.99.34-RXN] +synonym: "7-O-methylluteone,NADPH:O2 oxidoreductase activity" EXACT [EC:1.14.99.34] +synonym: "7-O-methylluteone:O2 oxidoreductase activity" EXACT [EC:1.14.99.34] +synonym: "monoprenyl isoflavone monooxygenase activity" EXACT [EC:1.14.99.34] +xref: EC:1.14.99.34 +xref: MetaCyc:1.14.99.34-RXN +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050603 +name: thiophene-2-carbonyl-CoA monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+)." [EC:1.14.99.35, RHEA:18929] +synonym: "thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.35] +synonym: "thiophene-2-carboxyl-CoA dehydrogenase activity" EXACT [EC:1.14.99.35] +synonym: "thiophene-2-carboxyl-CoA hydroxylase activity" EXACT [EC:1.14.99.35] +synonym: "thiophene-2-carboxyl-CoA monooxygenase activity" EXACT [EC:1.14.99.35] +xref: EC:1.14.99.35 +xref: KEGG_REACTION:R05742 +xref: MetaCyc:1.14.99.35-RXN +xref: RHEA:18929 +xref: UM-BBD_reactionID:r1235 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050604 +name: taxadiene 5-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol." [EC:1.14.99.37, RHEA:14049] +synonym: "taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)" EXACT [EC:1.14.99.37] +synonym: "taxadiene 5a-hydroxylase activity" EXACT [] +synonym: "taxadiene 5alpha-hydroxylase activity" EXACT [EC:1.14.99.37] +xref: EC:1.14.99.37 +xref: KEGG_REACTION:R06306 +xref: MetaCyc:1.14.99.37-RXN +xref: RHEA:14049 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0050605 +name: superoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin." [EC:1.15.1.2, MetaCyc:1.15.1.2-RXN] +synonym: "desulfoferrodoxin activity" RELATED [EC:1.15.1.2] +synonym: "neelaredoxin activity" RELATED [EC:1.15.1.2] +synonym: "rubredoxin:superoxide oxidoreductase activity" EXACT [EC:1.15.1.2] +xref: EC:1.15.1.2 +xref: MetaCyc:1.15.1.2-RXN +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016721 ! oxidoreductase activity, acting on superoxide radicals as acceptor + +[Term] +id: GO:0050606 +name: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH." [RHEA:29587] +synonym: "2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity" EXACT [EC:1.1.1.312] +synonym: "4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity" EXACT [EC:1.1.1.312] +synonym: "4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity" EXACT [EC:1.1.1.312] +synonym: "alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.1.1.312] +xref: EC:1.1.1.312 +xref: KEGG_REACTION:R04279 +xref: MetaCyc:1.2.1.45-RXN +xref: RHEA:29587 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050607 +name: mycothiol-dependent formaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+." [EC:1.1.1.306, MetaCyc:1.2.1.66-RXN] +synonym: "formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)" EXACT [] +synonym: "NAD/factor-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.306] +xref: EC:1.1.1.306 +xref: MetaCyc:1.2.1.66-RXN +xref: RHEA:28502 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050608 +name: vanillin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate." [EC:1.2.1.67, RHEA:13309] +synonym: "vanillin:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.67] +xref: EC:1.2.1.67 +xref: KEGG_REACTION:R05699 +xref: MetaCyc:1.2.1.67-RXN +xref: RHEA:13309 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050609 +name: phosphonate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate." [EC:1.20.1.1, RHEA:13173] +synonym: "NAD-dependent phosphite dehydrogenas activity" EXACT [EC:1.20.1.1] +synonym: "NAD:phosphite oxidoreductase activity" EXACT [EC:1.20.1.1] +synonym: "phosphite dehydrogenase activity" EXACT [EC:1.20.1.1] +synonym: "phosphonate:NAD+ oxidoreductase activity" EXACT [EC:1.20.1.1] +xref: EC:1.20.1.1 +xref: KEGG_REACTION:R05746 +xref: MetaCyc:1.20.1.1-RXN +xref: RHEA:13173 +xref: UM-BBD_reactionID:r1055 +is_a: GO:0050499 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor + +[Term] +id: GO:0050610 +name: methylarsonate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid." [EC:1.20.4.2, RHEA:15969] +synonym: "glutathione:methylarsonate oxidoreductase activity" EXACT [EC:1.20.4.2] +synonym: "MMA(V) reductase activity" EXACT [EC:1.20.4.2] +xref: EC:1.20.4.2 +xref: KEGG_REACTION:R05748 +xref: MetaCyc:1.20.4.2-RXN +xref: Reactome:R-HSA-5696230 "GSTO1 dimer reduces methylarsonate to methylarsonite" +xref: RHEA:15969 +xref: UM-BBD_reactionID:r0837 +is_a: GO:0030614 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor + +[Term] +id: GO:0050611 +name: arsenate reductase (azurin) activity +namespace: molecular_function +alt_id: GO:0018691 +def: "Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate." [EC:1.20.9.1, MetaCyc:1.20.98.1-RXN] +synonym: "arsenite oxidase activity" EXACT [EC:1.20.9.1] +synonym: "arsenite:azurin oxidoreductase activity" EXACT [EC:1.20.9.1] +xref: EC:1.20.9.1 +xref: MetaCyc:1.20.98.1-RXN +xref: UM-BBD_reactionID:r0634 +is_a: GO:0052882 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor + +[Term] +id: GO:0050612 +name: arsenate reductase (donor) activity +namespace: molecular_function +def: "Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+)." [EC:1.20.99.1, RHEA:18449] +synonym: "arsenate:(acceptor) oxidoreductase activity" EXACT [EC:1.20.99.1] +synonym: "arsenate:acceptor oxidoreductase activity" EXACT [EC:1.20.99.1] +xref: EC:1.20.99.1 +xref: KEGG_REACTION:R05752 +xref: MetaCyc:1.20.99.1-RXN +xref: RHEA:18449 +is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors + +[Term] +id: GO:0050613 +name: delta14-sterol reductase activity +namespace: molecular_function +alt_id: GO:0000251 +def: "Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol." [EC:1.3.1.70, MetaCyc:1.3.1.70-RXN] +comment: Note that zymosterol is cholesta-8,24-dien-3-ol. +synonym: "4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity" EXACT [EC:1.3.1.70] +synonym: "C-14 sterol reductase activity" EXACT [] +synonym: "D14-sterol reductase activity" EXACT [] +synonym: "sterol C-14 reductase activity" EXACT [] +synonym: "sterol C14-reductase activity" EXACT [EC:1.3.1.70] +xref: EC:1.3.1.70 +xref: MetaCyc:1.3.1.70-RXN +xref: Reactome:R-HSA-194674 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]" +xref: Reactome:R-HSA-194698 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]" +xref: RHEA:18561 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050614 +name: delta24-sterol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol." [EC:1.3.1.72, MetaCyc:1.3.1.72-RXN] +synonym: "D24-sterol reductase activity" EXACT [] +synonym: "lanosterol Delta(24)-reductase activity" NARROW [EC:1.3.1.72] +synonym: "lanosterol delta24-reductase activity" EXACT [EC:1.3.1.72] +synonym: "sterol:NADP+ delta24-oxidoreductase activity" EXACT [EC:1.3.1.72] +xref: EC:1.3.1.72 +xref: MetaCyc:1.3.1.72-RXN +xref: Reactome:R-HSA-196417 "Reduction of desmosterol to cholesterol" +xref: Reactome:R-HSA-6807064 "DHCR24 reduces ZYMOL to ZYMSTNL" +xref: RHEA:13685 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050615 +name: 1,2-dihydrovomilenine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH." [EC:1.3.1.73, RHEA:12320] +synonym: "17-O-acetylnorajmaline:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.73] +xref: EC:1.3.1.73 +xref: KEGG_REACTION:R05879 +xref: MetaCyc:1.3.1.73-RXN +xref: RHEA:12320 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050616 +name: secologanin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O." [EC:1.14.19.62, MetaCyc:1.3.3.9-RXN] +synonym: "loganin:oxygen oxidoreductase (ring-cleaving)" EXACT [EC:1.14.19.62] +xref: EC:1.14.19.62 +xref: MetaCyc:1.3.3.9-RXN +xref: RHEA:20585 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0050617 +name: 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.2, MetaCyc:1.3.7.2-RXN] +synonym: "PebA" RELATED [EC:1.3.7.2] +xref: EC:1.3.7.2 +xref: MetaCyc:1.3.7.2-RXN +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0050618 +name: phycoerythrobilin:ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin." [EC:1.3.7.3, MetaCyc:1.3.7.3-RXN] +synonym: "(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.3] +synonym: "PebB" RELATED [EC:1.3.7.3] +xref: EC:1.3.7.3 +xref: MetaCyc:1.3.7.3-RXN +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0050619 +name: phytochromobilin:ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.4, MetaCyc:1.3.7.4-RXN] +synonym: "(3Z)-phytochromobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.4] +synonym: "HY2" RELATED [EC:1.3.7.4] +synonym: "P-Phi-B synthase activity" RELATED [EC:1.3.7.4] +synonym: "PFB synthase activity" EXACT [EC:1.3.7.4] +synonym: "phytochromobilin synthase activity" EXACT [EC:1.3.7.4] +synonym: "PPhiB synthase activity" EXACT [EC:1.3.7.4] +xref: EC:1.3.7.4 +xref: MetaCyc:1.3.7.4-RXN +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0050620 +name: phycocyanobilin:ferredoxin oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.5, MetaCyc:1.3.7.5-RXN] +synonym: "(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.5] +xref: EC:1.3.7.5 +xref: MetaCyc:1.3.7.5-RXN +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0050621 +name: tryptophan alpha,beta-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+)." [EC:1.3.3.10, RHEA:19901] +comment: Note that this was EC:1.4.3.17. +synonym: "L-tryptophan 2',3'-oxidase activity" EXACT [EC:1.3.3.10] +synonym: "L-tryptophan alpha,beta-dehydrogenase activity" EXACT [EC:1.3.3.10] +synonym: "L-tryptophan:oxygen alpha,beta-oxidoreductase activity" EXACT [EC:1.3.3.10] +synonym: "tryptophan a,b-oxidase activity" EXACT [] +xref: EC:1.3.3.10 +xref: KEGG_REACTION:R05317 +xref: MetaCyc:1.4.3.17-RXN +xref: RHEA:19901 +is_a: GO:0016634 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor + +[Term] +id: GO:0050622 +name: glycine dehydrogenase (cyanide-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2." [EC:1.4.99.5, MetaCyc:1.4.99.5-RXN] +synonym: "glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)" EXACT [EC:1.4.99.5] +synonym: "HCN synthase activity" EXACT [EC:1.4.99.5] +synonym: "hydrogen cyanide synthase activity" EXACT [EC:1.4.99.5] +xref: EC:1.4.99.5 +xref: MetaCyc:1.4.99.5-RXN +xref: RHEA:15821 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0050623 +name: berberine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH." [EC:1.5.1.31, RHEA:21268] +synonym: "(R)-canadine synthase activity" EXACT [EC:1.5.1.31] +synonym: "(R)-tetrahydroberberine:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.31] +xref: EC:1.5.1.31 +xref: KEGG_REACTION:R07169 +xref: MetaCyc:1.5.1.31-RXN +xref: RHEA:21268 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050624 +name: vomilenine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine." [EC:1.5.1.32, RHEA:16409] +synonym: "1,2-dihydrovomilenine:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.32] +xref: EC:1.5.1.32 +xref: KEGG_REACTION:R05878 +xref: MetaCyc:1.5.1.32-RXN +xref: RHEA:16409 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0050625 +name: 2-hydroxy-1,4-benzoquinone reductase activity +namespace: molecular_function +alt_id: GO:0018540 +def: "Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+)." [EC:1.6.5.7, RHEA:12428] +synonym: "1,2,4-trihydroxybenzene:NAD oxidoreductase activity" EXACT [EC:1.6.5.7] +synonym: "1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity" EXACT [EC:1.6.5.7] +synonym: "2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity" EXACT [EC:1.6.5.7] +synonym: "hydroxybenzoquinone reductase activity" EXACT [EC:1.6.5.-] +synonym: "NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity" EXACT [EC:1.6.5.7] +xref: EC:1.6.5.7 +xref: KEGG_REACTION:R05399 +xref: MetaCyc:1.6.5.7-RXN +xref: RHEA:12428 +xref: UM-BBD_reactionID:r0667 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0050626 +name: trimethylamine-N-oxide reductase (cytochrome c) activity +namespace: molecular_function +def: "Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+." [EC:1.7.2.3, MetaCyc:1.7.2.3-RXN] +synonym: "TMAO reductase activity" EXACT [EC:1.7.2.3] +synonym: "TOR activity" EXACT [EC:1.7.2.3] +synonym: "trimethylamine:cytochrome c oxidoreductase activity" EXACT [EC:1.7.2.3] +xref: EC:1.7.2.3 +xref: MetaCyc:1.7.2.3-RXN +xref: Wikipedia:Trimethylamine_N-oxide_reductase +is_a: GO:0016662 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor + +[Term] +id: GO:0050627 +name: mycothione reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione." [EC:1.8.1.15, MetaCyc:1.8.1.15-RXN] +synonym: "mycothiol-disulfide reductase activity" EXACT [EC:1.8.1.15] +synonym: "mycothiol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.15] +xref: EC:1.8.1.15 +xref: MetaCyc:1.8.1.15-RXN +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050628 +name: 2-oxopropyl-CoM reductase (carboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH." [EC:1.8.1.5, RHEA:16977] +synonym: "2-KPCC activity" EXACT [EC:1.8.1.5] +synonym: "2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.8.1.5] +synonym: "NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity" EXACT [EC:1.8.1.5] +synonym: "NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity" EXACT [EC:1.8.1.5] +xref: EC:1.8.1.5 +xref: KEGG_REACTION:R05713 +xref: MetaCyc:1.8.1.5-RXN +xref: RHEA:16977 +xref: UM-BBD_reactionID:r0854 +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0050629 +name: tetrachloroethene reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor." [EC:1.21.99.5, MetaCyc:1.97.1.8-RXN] +synonym: "acceptor:trichloroethene oxidoreductase (chlorinating)" EXACT [EC:1.97.1.8] +synonym: "tetrachloroethene reductase activity" EXACT [EC:1.21.99.5] +xref: EC:1.21.99.5 +xref: MetaCyc:1.97.1.8-RXN +xref: RHEA:20353 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0050630 +name: (iso)eugenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol." [EC:2.1.1.146, MetaCyc:2.1.1.146-RXN] +synonym: "isoeugenol O-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity" EXACT [EC:2.1.1.146] +xref: EC:2.1.1.146 +xref: MetaCyc:2.1.1.146-RXN +xref: RHEA:17081 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0050631 +name: corydaline synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+)." [EC:2.1.1.147, RHEA:14773] +synonym: "S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity" EXACT [EC:2.1.1.147] +xref: EC:2.1.1.147 +xref: KEGG_REACTION:R07241 +xref: MetaCyc:2.1.1.147-RXN +xref: RHEA:14773 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0050632 +name: propionyl-CoA C2-trimethyltridecanoyltransferase activity +namespace: molecular_function +alt_id: GO:0004770 +def: "Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA." [EC:2.3.1.176, RHEA:10408] +synonym: "3-oxopristanoyl-CoA hydrolase activity" EXACT [EC:2.3.1.176] +synonym: "3-oxopristanoyl-CoA thiolase activity" EXACT [EC:2.3.1.176] +synonym: "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity" EXACT [EC:2.3.1.176] +synonym: "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity" EXACT [EC:2.3.1.176] +synonym: "oxopristanoyl-CoA thiolase activity" EXACT [EC:2.3.1.176] +synonym: "peroxisomal 3-oxoacyl coenzyme A thiolase" NARROW [EC:2.3.1.176] +synonym: "peroxisome sterol carrier protein thiolase" NARROW [EC:2.3.1.176] +synonym: "propionyl-CoA C(2)-trimethyltridecanoyltransferase activity" EXACT [] +synonym: "SCPx" RELATED [EC:2.3.1.176] +synonym: "sterol carrier protein" RELATED [EC:2.3.1.176] +synonym: "sterol carrier protein X-related thiolase activity" RELATED [] +xref: EC:2.3.1.176 +xref: KEGG_REACTION:R05330 +xref: MetaCyc:2.3.1.154-RXN +xref: Reactome:R-HSA-192341 "Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA" +xref: Reactome:R-HSA-193533 "Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA" +xref: Reactome:R-HSA-2066781 "Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx)" +xref: Reactome:R-HSA-390224 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA" +xref: RHEA:10408 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050633 +name: acetyl-CoA C-myristoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA." [EC:2.3.1.155, MetaCyc:2.3.1.155-RXN] +synonym: "3-oxopalmitoyl-CoA hydrolase activity" EXACT [EC:2.3.1.155] +synonym: "3-oxopalmitoyl-CoA-CoA acetyltransferase activity" EXACT [EC:2.3.1.155] +synonym: "myristoyl-CoA C-acetyltransferase activity" EXACT [EC:2.3.1.155] +synonym: "myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity" EXACT [EC:2.3.1.155] +xref: EC:2.3.1.155 +xref: MetaCyc:2.3.1.155-RXN +xref: RHEA:18161 +is_a: GO:0016408 ! C-acyltransferase activity +is_a: GO:0019107 ! myristoyltransferase activity + +[Term] +id: GO:0050634 +name: phloroisovalerophenone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one." [EC:2.3.1.156, MetaCyc:2.3.1.156-RXN] +synonym: "3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity" EXACT [EC:2.3.1.156] +synonym: "isovaleryl-CoA:malonyl-CoA acyltransferase activity" EXACT [EC:2.3.1.156] +synonym: "valerophenone synthase activity" EXACT [EC:2.3.1.156] +xref: EC:2.3.1.156 +xref: MetaCyc:2.3.1.156-RXN +xref: RHEA:23572 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050635 +name: acridone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O." [EC:2.3.1.159, RHEA:22224] +synonym: "malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.159] +xref: EC:2.3.1.159 +xref: KEGG_REACTION:R07250 +xref: MetaCyc:2.3.1.159-RXN +xref: RHEA:22224 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050636 +name: vinorine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine." [EC:2.3.1.160, RHEA:24016] +synonym: "acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)" EXACT [EC:2.3.1.160] +xref: EC:2.3.1.160 +xref: KEGG_REACTION:R05876 +xref: MetaCyc:2.3.1.160-RXN +xref: RHEA:24016 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050637 +name: lovastatin nonaketide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+)." [EC:2.3.1.161, RHEA:18565] +synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)" EXACT [EC:2.3.1.161] +xref: EC:2.3.1.161 +xref: KEGG_REACTION:R07251 +xref: MetaCyc:2.3.1.161-RXN +xref: RHEA:18565 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050638 +name: taxadien-5-alpha-ol O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate." [EC:2.3.1.162, RHEA:22028] +synonym: "acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity" EXACT [EC:2.3.1.162] +synonym: "acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity" EXACT [EC:2.3.1.162] +synonym: "acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity" EXACT [EC:2.3.1.162] +synonym: "taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity" EXACT [EC:2.3.1.162] +synonym: "taxadien-5a-ol O-acetyltransferase activity" EXACT [] +synonym: "taxadien-5alpha-ol O-acetyltransferase activity" EXACT [EC:2.3.1.162] +synonym: "taxadienol acetyltransferase activity" EXACT [EC:2.3.1.162] +xref: EC:2.3.1.162 +xref: KEGG_REACTION:R06307 +xref: MetaCyc:2.3.1.162-RXN +xref: RHEA:22028 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050639 +name: 10-hydroxytaxane O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C." [EC:2.3.1.163, RHEA:18837] +synonym: "acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity" EXACT [EC:2.3.1.163] +synonym: "acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity" EXACT [EC:2.3.1.163] +synonym: "acetyl-CoA:taxan-10beta-ol O-acetyltransferase" BROAD [EC:2.3.1.163] +xref: EC:2.3.1.163 +xref: KEGG_REACTION:R07252 +xref: MetaCyc:2.3.1.163-RXN +xref: RHEA:18837 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050640 +name: isopenicillin-N N-acyltransferase activity +namespace: molecular_function +alt_id: GO:0042319 +alt_id: GO:0045440 +def: "Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate." [EC:2.3.1.164, MetaCyc:2.3.1.164-RXN] +synonym: "acyl-CoA:isopenicillin N N-acyltransferase activity" EXACT [EC:2.3.1.164] +synonym: "acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity" EXACT [EC:2.3.1.164] +synonym: "acyl-coenzyme A:isopenicillin N acyltransferase activity" EXACT [EC:2.3.1.164] +synonym: "isopenicillin N:acyl-CoA acyltransferase activity" EXACT [EC:2.3.1.164] +synonym: "isopenicillin-N acyltransferase activity" EXACT [] +xref: EC:2.3.1.164 +xref: MetaCyc:2.3.1.164-RXN +xref: RHEA:20720 +is_a: GO:0016410 ! N-acyltransferase activity + +[Term] +id: GO:0050641 +name: 6-methylsalicylic acid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+)." [EC:2.3.1.165, RHEA:12240] +synonym: "6-MSAS activity" EXACT [EC:2.3.1.165] +synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)" EXACT [EC:2.3.1.165] +synonym: "MSAS activity" EXACT [EC:2.3.1.165] +xref: EC:2.3.1.165 +xref: KEGG_REACTION:R07253 +xref: MetaCyc:2.3.1.165-RXN +xref: RHEA:12240 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050642 +name: 2-alpha-hydroxytaxane 2-O-benzoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA." [EC:2.3.1.166, RHEA:18741] +synonym: "2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity" EXACT [EC:2.3.1.166] +synonym: "2a-hydroxytaxane 2-O-benzoyltransferase activity" EXACT [] +synonym: "2alpha-hydroxytaxane 2-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] +synonym: "benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity" EXACT [EC:2.3.1.166] +synonym: "benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] +synonym: "benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] +xref: EC:2.3.1.166 +xref: KEGG_REACTION:R06310 +xref: MetaCyc:2.3.1.166-RXN +xref: RHEA:18741 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050643 +name: 10-deacetylbaccatin III 10-O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA." [EC:2.3.1.167, RHEA:20137] +synonym: "acetyl-CoA:taxan-10beta-ol O-acetyltransferase" BROAD [EC:2.3.1.167] +xref: EC:2.3.1.167 +xref: KEGG_REACTION:R06311 +xref: MetaCyc:2.3.1.167-RXN +xref: RHEA:20137 +is_a: GO:0016413 ! O-acetyltransferase activity + +[Term] +id: GO:0050644 +name: cis-p-coumarate glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP." [EC:2.4.1.209, RHEA:13129] +synonym: "UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.209] +xref: EC:2.4.1.209 +xref: KEGG_REACTION:R05324 +xref: MetaCyc:2.4.1.209-RXN +xref: RHEA:13129 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050645 +name: limonoid glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP." [EC:2.4.1.210] +synonym: "LGTase activity" EXACT [EC:2.4.1.210] +synonym: "limonoid UDP-glucosyltransferase activity" EXACT [EC:2.4.1.210] +synonym: "uridine diphosphoglucose-limonoid glucosyltransferase activity" EXACT [EC:2.4.1.210] +xref: EC:2.4.1.210 +xref: MetaCyc:2.4.1.210-RXN +xref: RHEA:11256 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0050646 +name: 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] +synonym: "5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0036041 ! long-chain fatty acid binding +is_a: GO:0050542 ! icosanoid binding + +[Term] +id: GO:0050647 +name: 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] +synonym: "5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] +is_a: GO:0036041 ! long-chain fatty acid binding +is_a: GO:0050542 ! icosanoid binding + +[Term] +id: GO:0050648 +name: 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] +synonym: "5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] +is_a: GO:0036041 ! long-chain fatty acid binding +is_a: GO:0050542 ! icosanoid binding + +[Term] +id: GO:0050649 +name: testosterone 6-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O." [GOC:ai, PMID:11726664] +synonym: "testosterone 6b-hydroxylase activity" EXACT [] +is_a: GO:0008395 ! steroid hydroxylase activity + +[Term] +id: GO:0050650 +name: chondroitin sulfate proteoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate." [GOC:ai] +synonym: "chondroitin sulfate proteoglycan anabolism" EXACT [] +synonym: "chondroitin sulfate proteoglycan biosynthesis" EXACT [] +synonym: "chondroitin sulfate proteoglycan formation" EXACT [] +synonym: "chondroitin sulfate proteoglycan synthesis" EXACT [] +synonym: "chondroitin sulphate proteoglycan biosynthesis" EXACT [] +synonym: "chondroitin sulphate proteoglycan biosynthetic process" EXACT [] +is_a: GO:0030166 ! proteoglycan biosynthetic process +is_a: GO:0050654 ! chondroitin sulfate proteoglycan metabolic process + +[Term] +id: GO:0050651 +name: dermatan sulfate proteoglycan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units." [GOC:ai] +synonym: "chondroitin sulfate B proteoglycan biosynthesis" EXACT [] +synonym: "chondroitin sulfate B proteoglycan biosynthetic process" EXACT [] +synonym: "dermatan sulfate proteoglycan anabolism" EXACT [] +synonym: "dermatan sulfate proteoglycan biosynthesis" EXACT [] +synonym: "dermatan sulfate proteoglycan formation" EXACT [] +synonym: "dermatan sulfate proteoglycan synthesis" EXACT [] +synonym: "dermatan sulphate proteoglycan biosynthesis" EXACT [] +synonym: "dermatan sulphate proteoglycan biosynthetic process" EXACT [] +is_a: GO:0030166 ! proteoglycan biosynthetic process +is_a: GO:0050655 ! dermatan sulfate proteoglycan metabolic process + +[Term] +id: GO:0050652 +name: dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process +namespace: biological_process +def: "The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate." [GOC:ai, PMID:11788602] +synonym: "chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [] +synonym: "chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [] +synonym: "chondroitin sulfate B proteoglycan chain elongation" EXACT [] +synonym: "dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [] +synonym: "dermatan sulfate proteoglycan chain elongation" EXACT [] +synonym: "dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [] +synonym: "dermatan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [] +synonym: "dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [] +synonym: "dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [] +synonym: "dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +relationship: part_of GO:0050651 ! dermatan sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0050653 +name: chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process +namespace: biological_process +def: "The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate." [GOC:ai, PMID:11788602] +synonym: "chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [] +synonym: "chondroitin sulfate proteoglycan chain elongation" EXACT [] +synonym: "chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [] +synonym: "chondroitin sulfate proteoglycan formation, polysaccharide chain formation" EXACT [] +synonym: "chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [] +synonym: "chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [] +synonym: "chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +relationship: part_of GO:0050650 ! chondroitin sulfate proteoglycan biosynthetic process + +[Term] +id: GO:0050654 +name: chondroitin sulfate proteoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate." [GOC:ai] +synonym: "chondroitin sulfate proteoglycan metabolism" EXACT [] +synonym: "chondroitin sulphate proteoglycan metabolic process" EXACT [] +synonym: "chondroitin sulphate proteoglycan metabolism" EXACT [] +is_a: GO:0006029 ! proteoglycan metabolic process + +[Term] +id: GO:0050655 +name: dermatan sulfate proteoglycan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units." [GOC:ai] +synonym: "chondroitin sulfate B proteoglycan metabolic process" EXACT [] +synonym: "chondroitin sulfate B proteoglycan metabolism" EXACT [] +synonym: "dermatan sulfate proteoglycan metabolism" EXACT [] +synonym: "dermatan sulphate proteoglycan metabolic process" EXACT [] +synonym: "dermatan sulphate proteoglycan metabolism" EXACT [] +is_a: GO:0006029 ! proteoglycan metabolic process + +[Term] +id: GO:0050656 +name: 3'-phosphoadenosine 5'-phosphosulfate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems." [GOC:ai] +synonym: "3'-phosphoadenosine 5'-phosphosulphate binding" EXACT [] +synonym: "3'-phosphoadenylyl-sulfate binding" EXACT [] +synonym: "adenosine 3'-phosphate 5'-phosphosulfate binding" EXACT [] +synonym: "PAPS binding" EXACT [] +synonym: "phosphoadenosine phosphosulfate binding" EXACT [] +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding + +[Term] +id: GO:0050657 +name: nucleic acid transport +namespace: biological_process +def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] +is_a: GO:0015931 ! nucleobase-containing compound transport + +[Term] +id: GO:0050658 +name: RNA transport +namespace: biological_process +def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050657 ! nucleic acid transport +is_a: GO:0051236 ! establishment of RNA localization + +[Term] +id: GO:0050659 +name: N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate." [EC:2.8.2.33] +comment: Consider instead annotating to the individual reactions: 'chondroitin 6-sulfotransferase activity ; GO:0008459' and 'dermatan 6-sulfotransferase activity ; GO:0036443'. +synonym: "3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity" EXACT [EC:2.8.2.33] +synonym: "GalNAc4S-6ST" RELATED [EC:2.8.2.33] +synonym: "N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity" EXACT [EC:2.8.2.33] +xref: EC:2.8.2.33 +xref: KEGG_REACTION:R02181 +xref: KEGG_REACTION:R07288 +xref: MetaCyc:RXN-7953 +xref: MetaCyc:RXN-7954 +xref: Reactome:R-HSA-2018659 "Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15" +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050660 +name: flavin adenine dinucleotide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2." [GOC:ai, GOC:imk, ISBN:0198506732] +synonym: "FAD or FADH2 binding" EXACT [] +synonym: "flavine-adenine dinucleotide binding" EXACT [] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0050662 ! coenzyme binding + +[Term] +id: GO:0050661 +name: NADP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH." [GOC:ai] +synonym: "NADP or NADPH binding" RELATED [GOC:mah] +synonym: "NADP+ or NADPH binding" RELATED [] +synonym: "nicotinamide adenine dinucleotide phosphate binding" EXACT [] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0050662 ! coenzyme binding + +[Term] +id: GO:0050662 +name: coenzyme binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [ISBN:0198506732] +subset: goslim_metagenomics +is_a: GO:0048037 ! cofactor binding + +[Term] +id: GO:0050663 +name: cytokine secretion +namespace: biological_process +def: "The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." [GOC:ai, GOC:bf, ISBN:0198599471] +synonym: "interferon secretion" NARROW [GOC:add, GOC:mah] +synonym: "interleukin secretion" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] +is_a: GO:0009306 ! protein secretion +is_a: GO:0023061 ! signal release +relationship: part_of GO:0001816 ! cytokine production + +[Term] +id: GO:0050664 +name: oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule." [EC:1.6.3.-] +synonym: "oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor" RELATED [] +xref: EC:1.6.3 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0050665 +name: hydrogen peroxide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA." [GOC:ai] +synonym: "H2O2 biosynthetic process" EXACT [GOC:mah] +synonym: "hydrogen peroxide anabolism" EXACT [] +synonym: "hydrogen peroxide biosynthesis" EXACT [] +synonym: "hydrogen peroxide formation" EXACT [] +synonym: "hydrogen peroxide generation" EXACT [] +synonym: "hydrogen peroxide synthesis" EXACT [] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0042743 ! hydrogen peroxide metabolic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1903409 ! reactive oxygen species biosynthetic process + +[Term] +id: GO:0050666 +name: regulation of homocysteine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid." [GOC:ai] +synonym: "regulation of Hcy metabolic process" EXACT [] +synonym: "regulation of Hcy metabolism" EXACT [] +synonym: "regulation of homocysteine metabolism" EXACT [] +is_a: GO:0031335 ! regulation of sulfur amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050667 ! homocysteine metabolic process +relationship: regulates GO:0050667 ! homocysteine metabolic process + +[Term] +id: GO:0050667 +name: homocysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine." [ISBN:0198506732] +synonym: "Hcy metabolic process" EXACT [] +synonym: "Hcy metabolism" EXACT [] +synonym: "homocysteine metabolism" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0050668 +name: positive regulation of homocysteine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine." [GOC:ai] +synonym: "activation of homocysteine metabolic process" NARROW [] +synonym: "positive regulation of Hcy metabolic process" EXACT [] +synonym: "positive regulation of Hcy metabolism" EXACT [] +synonym: "positive regulation of homocysteine metabolism" EXACT [] +synonym: "stimulation of homocysteine metabolic process" NARROW [] +synonym: "up regulation of homocysteine metabolic process" EXACT [] +synonym: "up-regulation of homocysteine metabolic process" EXACT [] +synonym: "upregulation of homocysteine metabolic process" EXACT [] +is_a: GO:0031337 ! positive regulation of sulfur amino acid metabolic process +is_a: GO:0050666 ! regulation of homocysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050667 ! homocysteine metabolic process +relationship: positively_regulates GO:0050667 ! homocysteine metabolic process + +[Term] +id: GO:0050669 +name: negative regulation of homocysteine metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine." [GOC:ai] +synonym: "down regulation of homocysteine metabolic process" EXACT [] +synonym: "down-regulation of homocysteine metabolic process" EXACT [] +synonym: "downregulation of homocysteine metabolic process" EXACT [] +synonym: "inhibition of homocysteine metabolic process" NARROW [] +synonym: "negative regulation of Hcy metabolic process" EXACT [] +synonym: "negative regulation of Hcy metabolism" EXACT [] +synonym: "negative regulation of homocysteine metabolism" EXACT [] +is_a: GO:0031336 ! negative regulation of sulfur amino acid metabolic process +is_a: GO:0050666 ! regulation of homocysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050667 ! homocysteine metabolic process +relationship: negatively_regulates GO:0050667 ! homocysteine metabolic process + +[Term] +id: GO:0050670 +name: regulation of lymphocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] +is_a: GO:0032944 ! regulation of mononuclear cell proliferation +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046651 ! lymphocyte proliferation +relationship: regulates GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0050671 +name: positive regulation of lymphocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] +synonym: "activation of lymphocyte proliferation" NARROW [] +synonym: "stimulation of lymphocyte proliferation" NARROW [] +synonym: "up regulation of lymphocyte proliferation" EXACT [] +synonym: "up-regulation of lymphocyte proliferation" EXACT [] +synonym: "upregulation of lymphocyte proliferation" EXACT [] +is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation +is_a: GO:0050670 ! regulation of lymphocyte proliferation +is_a: GO:0051251 ! positive regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046651 ! lymphocyte proliferation +relationship: positively_regulates GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0050672 +name: negative regulation of lymphocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] +synonym: "down regulation of lymphocyte proliferation" EXACT [] +synonym: "down-regulation of lymphocyte proliferation" EXACT [] +synonym: "downregulation of lymphocyte proliferation" EXACT [] +synonym: "inhibition of lymphocyte proliferation" NARROW [] +is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation +is_a: GO:0050670 ! regulation of lymphocyte proliferation +is_a: GO:0051250 ! negative regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046651 ! lymphocyte proliferation +relationship: negatively_regulates GO:0046651 ! lymphocyte proliferation + +[Term] +id: GO:0050673 +name: epithelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0050674 +name: urothelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria." [ISBN:0721662544] +is_a: GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0050675 +name: regulation of urothelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of urothelial cell proliferation." [GOC:ai] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050674 ! urothelial cell proliferation +relationship: regulates GO:0050674 ! urothelial cell proliferation + +[Term] +id: GO:0050676 +name: negative regulation of urothelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation." [GOC:ai] +synonym: "down regulation of urothelial cell proliferation" EXACT [] +synonym: "down-regulation of urothelial cell proliferation" EXACT [] +synonym: "downregulation of urothelial cell proliferation" EXACT [] +synonym: "inhibition of urothelial cell proliferation" NARROW [] +is_a: GO:0050675 ! regulation of urothelial cell proliferation +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050674 ! urothelial cell proliferation +relationship: negatively_regulates GO:0050674 ! urothelial cell proliferation + +[Term] +id: GO:0050677 +name: positive regulation of urothelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of urothelial cell proliferation." [GOC:ai] +synonym: "activation of urothelial cell proliferation" NARROW [] +synonym: "stimulation of urothelial cell proliferation" NARROW [] +synonym: "up regulation of urothelial cell proliferation" EXACT [] +synonym: "up-regulation of urothelial cell proliferation" EXACT [] +synonym: "upregulation of urothelial cell proliferation" EXACT [] +is_a: GO:0050675 ! regulation of urothelial cell proliferation +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050674 ! urothelial cell proliferation +relationship: positively_regulates GO:0050674 ! urothelial cell proliferation + +[Term] +id: GO:0050678 +name: regulation of epithelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050673 ! epithelial cell proliferation +relationship: regulates GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0050679 +name: positive regulation of epithelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] +synonym: "activation of epithelial cell proliferation" NARROW [] +synonym: "stimulation of epithelial cell proliferation" NARROW [] +synonym: "up regulation of epithelial cell proliferation" EXACT [] +synonym: "up-regulation of epithelial cell proliferation" EXACT [] +synonym: "upregulation of epithelial cell proliferation" EXACT [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050673 ! epithelial cell proliferation +relationship: positively_regulates GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0050680 +name: negative regulation of epithelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] +synonym: "down regulation of epithelial cell proliferation" EXACT [] +synonym: "down-regulation of epithelial cell proliferation" EXACT [] +synonym: "downregulation of epithelial cell proliferation" EXACT [] +synonym: "inhibition of epithelial cell proliferation" NARROW [] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050673 ! epithelial cell proliferation +relationship: negatively_regulates GO:0050673 ! epithelial cell proliferation + +[Term] +id: GO:0050681 +name: androgen receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an androgen receptor." [GOC:ai] +synonym: "AR binding" EXACT [] +is_a: GO:0016922 ! nuclear receptor binding +is_a: GO:0035258 ! steroid hormone receptor binding + +[Term] +id: GO:0050682 +name: AF-2 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation." [PMID:9682036] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050683 +name: AF-1 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor." [PMID:9682036] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050684 +name: regulation of mRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide." [GOC:ai] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006397 ! mRNA processing +relationship: regulates GO:0006397 ! mRNA processing + +[Term] +id: GO:0050685 +name: positive regulation of mRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA processing." [GOC:ai] +synonym: "activation of mRNA processing" NARROW [] +synonym: "stimulation of mRNA processing" NARROW [] +synonym: "up regulation of mRNA processing" EXACT [] +synonym: "up-regulation of mRNA processing" EXACT [] +synonym: "upregulation of mRNA processing" EXACT [] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0050684 ! regulation of mRNA processing +is_a: GO:1903313 ! positive regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006397 ! mRNA processing +relationship: positively_regulates GO:0006397 ! mRNA processing + +[Term] +id: GO:0050686 +name: negative regulation of mRNA processing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing." [GOC:ai] +synonym: "down regulation of mRNA processing" EXACT [] +synonym: "down-regulation of mRNA processing" EXACT [] +synonym: "downregulation of mRNA processing" EXACT [] +synonym: "inhibition of mRNA processing" NARROW [] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0050684 ! regulation of mRNA processing +is_a: GO:1903312 ! negative regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006397 ! mRNA processing +relationship: negatively_regulates GO:0006397 ! mRNA processing + +[Term] +id: GO:0050687 +name: negative regulation of defense response to virus +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication." [GOC:ai] +synonym: "down regulation of antiviral response" EXACT [] +synonym: "down-regulation of antiviral response" EXACT [] +synonym: "downregulation of antiviral response" EXACT [] +synonym: "inhibition of antiviral response" NARROW [] +synonym: "negative regulation of antiviral response" EXACT [GOC:dph] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0050688 ! regulation of defense response to virus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051607 ! defense response to virus +relationship: negatively_regulates GO:0051607 ! defense response to virus + +[Term] +id: GO:0050688 +name: regulation of defense response to virus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism." [GOC:ai] +synonym: "regulation of antiviral response" EXACT [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051607 ! defense response to virus +relationship: regulates GO:0051607 ! defense response to virus + +[Term] +id: GO:0050689 +name: negative regulation of defense response to virus by host +namespace: biological_process +def: "Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ai, GOC:dph, GOC:tb] +synonym: "down regulation of antiviral response by host" EXACT [] +synonym: "down-regulation of antiviral response by host" EXACT [] +synonym: "downregulation of antiviral response by host" EXACT [] +synonym: "inhibition of antiviral response by host" NARROW [] +synonym: "negative regulation by host of antiviral response" EXACT [] +synonym: "negative regulation of antiviral response by host" EXACT [GOC:dph, GOC:tb] +is_a: GO:0050687 ! negative regulation of defense response to virus +is_a: GO:0050691 ! regulation of defense response to virus by host + +[Term] +id: GO:0050690 +name: regulation of defense response to virus by virus +namespace: biological_process +def: "Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism." [GOC:ai, GOC:dph] +synonym: "regulation by virus of antiviral response" EXACT [] +synonym: "regulation of antiviral response by virus" EXACT [GOC:dph] +synonym: "viral regulation of antiviral response" EXACT [] +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0050691 +name: regulation of defense response to virus by host +namespace: biological_process +def: "Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism." [GOC:ai, GOC:dph] +synonym: "host regulation of antiviral response" EXACT [] +synonym: "regulation by host of antiviral response" EXACT [] +synonym: "regulation of antiviral response by host" RELATED [GOC:dph] +is_a: GO:0050688 ! regulation of defense response to virus + +[Term] +id: GO:0050692 +name: DNA binding domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein." [PMID:9682036] +synonym: "DBD binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050693 +name: LBD domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket." [PMID:9682036] +synonym: "ligand binding domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050694 +name: galactose 3-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc." [GOC:ai, PMID:11323440, PMID:11356829] +synonym: "Gal-3-O-sulfotransferase activity" EXACT [] +synonym: "galactose 3-O-sulphotransferase activity" EXACT [] +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050695 +name: benzoylformate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoylformate = benzaldehyde + CO2." [EC:4.1.1.7, MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN] +synonym: "benzoylformate carboxy-lyase (benzaldehyde-forming)" EXACT [EC:4.1.1.7] +synonym: "benzoylformate carboxy-lyase activity" EXACT [EC:4.1.1.7] +synonym: "phenylglyoxylate decarboxylase activity" EXACT [] +xref: EC:4.1.1.7 +xref: MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN +xref: RHEA:23368 +xref: UM-BBD_reactionID:r1049 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0050696 +name: trichloroethylene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent." [GOC:ai] +synonym: "trichloroethene catabolic process" EXACT [] +synonym: "trichloroethene catabolism" EXACT [] +synonym: "trichloroethylene breakdown" EXACT [] +synonym: "trichloroethylene catabolism" EXACT [] +synonym: "trichloroethylene degradation" EXACT [] +is_a: GO:0018979 ! trichloroethylene metabolic process +is_a: GO:0042205 ! chlorinated hydrocarbon catabolic process +is_a: GO:0042737 ! drug catabolic process + +[Term] +id: GO:0050697 +name: 1,1,2-trichloroethene reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene." [MetaCyc:TCEREDCHLOR-RXN, UM-BBD_enzymeID:e0271] +synonym: "1,1,2-trichloroethylene reductive dehalogenase activity" EXACT [] +synonym: "TCE-reductive dehalogenase activity" EXACT [] +xref: MetaCyc:TCEREDCHLOR-RXN +xref: UM-BBD_enzymeID:e0271 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0050698 +name: proteoglycan sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans." [EC:2.8.2.-, GOC:ai] +synonym: "proteoglycan sulfate transfer" RELATED [] +synonym: "proteoglycan sulphotransferase activity" EXACT [] +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0050699 +name: WW domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions." [PMID:14531730] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050700 +name: CARD domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family." [PMID:12054670] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050701 +name: interleukin-1 secretion +namespace: biological_process +def: "The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response." [GOC:ai, ISBN:0198506732] +synonym: "IL-1 secretion" EXACT [] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032612 ! interleukin-1 production + +[Term] +id: GO:0050702 +name: interleukin-1 beta secretion +namespace: biological_process +def: "The regulated release of interleukin 1 beta from a cell." [GOC:ai] +synonym: "IL-1b secretion" EXACT [] +is_a: GO:0050701 ! interleukin-1 secretion +relationship: part_of GO:0032611 ! interleukin-1 beta production + +[Term] +id: GO:0050703 +name: interleukin-1 alpha secretion +namespace: biological_process +def: "The regulated release of interleukin-1 alpha from a cell." [GOC:ai] +synonym: "IL-1a secretion" EXACT [] +is_a: GO:0050701 ! interleukin-1 secretion +relationship: part_of GO:0032610 ! interleukin-1 alpha production + +[Term] +id: GO:0050704 +name: regulation of interleukin-1 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell." [GOC:ai] +is_a: GO:0032652 ! regulation of interleukin-1 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050701 ! interleukin-1 secretion +relationship: regulates GO:0050701 ! interleukin-1 secretion + +[Term] +id: GO:0050705 +name: regulation of interleukin-1 alpha secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell." [GOC:ai] +is_a: GO:0032650 ! regulation of interleukin-1 alpha production +is_a: GO:0050704 ! regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050703 ! interleukin-1 alpha secretion +relationship: regulates GO:0050703 ! interleukin-1 alpha secretion + +[Term] +id: GO:0050706 +name: regulation of interleukin-1 beta secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell." [GOC:ai] +is_a: GO:0032651 ! regulation of interleukin-1 beta production +is_a: GO:0050704 ! regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050702 ! interleukin-1 beta secretion +relationship: regulates GO:0050702 ! interleukin-1 beta secretion + +[Term] +id: GO:0050707 +name: regulation of cytokine secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell." [GOC:ai] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050663 ! cytokine secretion +relationship: regulates GO:0050663 ! cytokine secretion + +[Term] +id: GO:0050708 +name: regulation of protein secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] +is_a: GO:0002791 ! regulation of peptide secretion +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009306 ! protein secretion +relationship: regulates GO:0009306 ! protein secretion + +[Term] +id: GO:0050709 +name: negative regulation of protein secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] +synonym: "down regulation of protein secretion" EXACT [] +synonym: "down-regulation of protein secretion" EXACT [] +synonym: "downregulation of protein secretion" EXACT [] +synonym: "inhibition of protein secretion" NARROW [] +is_a: GO:0002792 ! negative regulation of peptide secretion +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:1903531 ! negative regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009306 ! protein secretion +relationship: negatively_regulates GO:0009306 ! protein secretion + +[Term] +id: GO:0050710 +name: negative regulation of cytokine secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell." [GOC:ai] +synonym: "down regulation of cytokine secretion" EXACT [] +synonym: "down-regulation of cytokine secretion" EXACT [] +synonym: "downregulation of cytokine secretion" EXACT [] +synonym: "inhibition of cytokine secretion" NARROW [] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0050707 ! regulation of cytokine secretion +is_a: GO:0050709 ! negative regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050663 ! cytokine secretion +relationship: negatively_regulates GO:0050663 ! cytokine secretion + +[Term] +id: GO:0050711 +name: negative regulation of interleukin-1 secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell." [GOC:ai] +synonym: "down regulation of interleukin-1 secretion" EXACT [] +synonym: "down-regulation of interleukin-1 secretion" EXACT [] +synonym: "downregulation of interleukin-1 secretion" EXACT [] +synonym: "inhibition of interleukin-1 secretion" NARROW [] +is_a: GO:0032692 ! negative regulation of interleukin-1 production +is_a: GO:0050704 ! regulation of interleukin-1 secretion +is_a: GO:0050710 ! negative regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050701 ! interleukin-1 secretion +relationship: negatively_regulates GO:0050701 ! interleukin-1 secretion + +[Term] +id: GO:0050712 +name: negative regulation of interleukin-1 alpha secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell." [GOC:ai] +synonym: "down regulation of interleukin-1 alpha secretion" EXACT [] +synonym: "down-regulation of interleukin-1 alpha secretion" EXACT [] +synonym: "downregulation of interleukin-1 alpha secretion" EXACT [] +synonym: "inhibition of interleukin-1 alpha secretion" NARROW [] +is_a: GO:0032690 ! negative regulation of interleukin-1 alpha production +is_a: GO:0050705 ! regulation of interleukin-1 alpha secretion +is_a: GO:0050711 ! negative regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050703 ! interleukin-1 alpha secretion +relationship: negatively_regulates GO:0050703 ! interleukin-1 alpha secretion + +[Term] +id: GO:0050713 +name: negative regulation of interleukin-1 beta secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell." [GOC:ai] +synonym: "down regulation of interleukin-1 beta secretion" EXACT [] +synonym: "down-regulation of interleukin-1 beta secretion" EXACT [] +synonym: "downregulation of interleukin-1 beta secretion" EXACT [] +synonym: "inhibition of interleukin-1 beta secretion" NARROW [] +is_a: GO:0032691 ! negative regulation of interleukin-1 beta production +is_a: GO:0050706 ! regulation of interleukin-1 beta secretion +is_a: GO:0050711 ! negative regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050702 ! interleukin-1 beta secretion +relationship: negatively_regulates GO:0050702 ! interleukin-1 beta secretion + +[Term] +id: GO:0050714 +name: positive regulation of protein secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] +synonym: "activation of protein secretion" NARROW [] +synonym: "stimulation of protein secretion" NARROW [] +synonym: "up regulation of protein secretion" EXACT [] +synonym: "up-regulation of protein secretion" EXACT [] +synonym: "upregulation of protein secretion" EXACT [] +is_a: GO:0002793 ! positive regulation of peptide secretion +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:1903532 ! positive regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009306 ! protein secretion +relationship: positively_regulates GO:0009306 ! protein secretion + +[Term] +id: GO:0050715 +name: positive regulation of cytokine secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell." [GOC:ai] +synonym: "activation of cytokine secretion" NARROW [] +synonym: "stimulation of cytokine secretion" NARROW [] +synonym: "up regulation of cytokine secretion" EXACT [] +synonym: "up-regulation of cytokine secretion" EXACT [] +synonym: "upregulation of cytokine secretion" EXACT [] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0050707 ! regulation of cytokine secretion +is_a: GO:0050714 ! positive regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050663 ! cytokine secretion +relationship: positively_regulates GO:0050663 ! cytokine secretion + +[Term] +id: GO:0050716 +name: positive regulation of interleukin-1 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell." [GOC:ai] +synonym: "activation of interleukin-1 secretion" NARROW [] +synonym: "stimulation of interleukin-1 secretion" NARROW [] +synonym: "up regulation of interleukin-1 secretion" EXACT [] +synonym: "up-regulation of interleukin-1 secretion" EXACT [] +synonym: "upregulation of interleukin-1 secretion" EXACT [] +is_a: GO:0032732 ! positive regulation of interleukin-1 production +is_a: GO:0050704 ! regulation of interleukin-1 secretion +is_a: GO:0050715 ! positive regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050701 ! interleukin-1 secretion +relationship: positively_regulates GO:0050701 ! interleukin-1 secretion + +[Term] +id: GO:0050717 +name: positive regulation of interleukin-1 alpha secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell." [GOC:ai] +synonym: "activation of interleukin-1 alpha secretion" NARROW [] +synonym: "stimulation of interleukin-1 alpha secretion" NARROW [] +synonym: "up regulation of interleukin-1 alpha secretion" EXACT [] +synonym: "up-regulation of interleukin-1 alpha secretion" EXACT [] +synonym: "upregulation of interleukin-1 alpha secretion" EXACT [] +is_a: GO:0032730 ! positive regulation of interleukin-1 alpha production +is_a: GO:0050705 ! regulation of interleukin-1 alpha secretion +is_a: GO:0050716 ! positive regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050703 ! interleukin-1 alpha secretion +relationship: positively_regulates GO:0050703 ! interleukin-1 alpha secretion + +[Term] +id: GO:0050718 +name: positive regulation of interleukin-1 beta secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell." [GOC:ai] +synonym: "activation of interleukin-1 beta secretion" NARROW [] +synonym: "stimulation of interleukin-1 beta secretion" NARROW [] +synonym: "up regulation of interleukin-1 beta secretion" EXACT [] +synonym: "up-regulation of interleukin-1 beta secretion" EXACT [] +synonym: "upregulation of interleukin-1 beta secretion" EXACT [] +is_a: GO:0032731 ! positive regulation of interleukin-1 beta production +is_a: GO:0050706 ! regulation of interleukin-1 beta secretion +is_a: GO:0050716 ! positive regulation of interleukin-1 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050702 ! interleukin-1 beta secretion +relationship: positively_regulates GO:0050702 ! interleukin-1 beta secretion + +[Term] +id: GO:0050719 +name: interleukin-1 alpha biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] +synonym: "interleukin-1 alpha anabolism" EXACT [] +synonym: "interleukin-1 alpha biosynthesis" EXACT [] +synonym: "interleukin-1 alpha formation" EXACT [] +synonym: "interleukin-1 alpha synthesis" EXACT [] +is_a: GO:0042222 ! interleukin-1 biosynthetic process +relationship: part_of GO:0032610 ! interleukin-1 alpha production + +[Term] +id: GO:0050720 +name: interleukin-1 beta biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] +synonym: "interleukin-1 beta anabolism" EXACT [] +synonym: "interleukin-1 beta biosynthesis" EXACT [] +synonym: "interleukin-1 beta formation" EXACT [] +synonym: "interleukin-1 beta synthesis" EXACT [] +is_a: GO:0042222 ! interleukin-1 biosynthetic process +relationship: part_of GO:0032611 ! interleukin-1 beta production + +[Term] +id: GO:0050721 +name: regulation of interleukin-1 alpha biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] +synonym: "regulation of interleukin-1 alpha anabolism" EXACT [] +synonym: "regulation of interleukin-1 alpha biosynthesis" EXACT [] +synonym: "regulation of interleukin-1 alpha formation" EXACT [] +synonym: "regulation of interleukin-1 alpha synthesis" EXACT [] +is_a: GO:0032650 ! regulation of interleukin-1 alpha production +is_a: GO:0045360 ! regulation of interleukin-1 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050719 ! interleukin-1 alpha biosynthetic process +relationship: regulates GO:0050719 ! interleukin-1 alpha biosynthetic process + +[Term] +id: GO:0050722 +name: regulation of interleukin-1 beta biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] +synonym: "regulation of interleukin-1 beta anabolism" EXACT [] +synonym: "regulation of interleukin-1 beta biosynthesis" EXACT [] +synonym: "regulation of interleukin-1 beta formation" EXACT [] +synonym: "regulation of interleukin-1 beta synthesis" EXACT [] +is_a: GO:0032651 ! regulation of interleukin-1 beta production +is_a: GO:0045360 ! regulation of interleukin-1 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050720 ! interleukin-1 beta biosynthetic process +relationship: regulates GO:0050720 ! interleukin-1 beta biosynthetic process + +[Term] +id: GO:0050723 +name: negative regulation of interleukin-1 alpha biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] +synonym: "down regulation of interleukin-1 alpha biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-1 alpha biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-1 alpha biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-1 alpha biosynthetic process" NARROW [] +synonym: "negative regulation of interleukin-1 alpha anabolism" EXACT [] +synonym: "negative regulation of interleukin-1 alpha biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-1 alpha formation" EXACT [] +synonym: "negative regulation of interleukin-1 alpha synthesis" EXACT [] +is_a: GO:0032690 ! negative regulation of interleukin-1 alpha production +is_a: GO:0045361 ! negative regulation of interleukin-1 biosynthetic process +is_a: GO:0050721 ! regulation of interleukin-1 alpha biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050719 ! interleukin-1 alpha biosynthetic process +relationship: negatively_regulates GO:0050719 ! interleukin-1 alpha biosynthetic process + +[Term] +id: GO:0050724 +name: negative regulation of interleukin-1 beta biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] +synonym: "down regulation of interleukin-1 beta biosynthetic process" EXACT [] +synonym: "down-regulation of interleukin-1 beta biosynthetic process" EXACT [] +synonym: "downregulation of interleukin-1 beta biosynthetic process" EXACT [] +synonym: "inhibition of interleukin-1 beta biosynthetic process" NARROW [] +synonym: "negative regulation of interleukin-1 beta anabolism" EXACT [] +synonym: "negative regulation of interleukin-1 beta biosynthesis" EXACT [] +synonym: "negative regulation of interleukin-1 beta formation" EXACT [] +synonym: "negative regulation of interleukin-1 beta synthesis" EXACT [] +is_a: GO:0032691 ! negative regulation of interleukin-1 beta production +is_a: GO:0045361 ! negative regulation of interleukin-1 biosynthetic process +is_a: GO:0050722 ! regulation of interleukin-1 beta biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050720 ! interleukin-1 beta biosynthetic process +relationship: negatively_regulates GO:0050720 ! interleukin-1 beta biosynthetic process + +[Term] +id: GO:0050725 +name: positive regulation of interleukin-1 beta biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] +synonym: "activation of interleukin-1 beta biosynthetic process" NARROW [] +synonym: "positive regulation of interleukin-1 beta anabolism" EXACT [] +synonym: "positive regulation of interleukin-1 beta biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-1 beta formation" EXACT [] +synonym: "positive regulation of interleukin-1 beta synthesis" EXACT [] +synonym: "stimulation of interleukin-1 beta biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-1 beta biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-1 beta biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-1 beta biosynthetic process" EXACT [] +is_a: GO:0032731 ! positive regulation of interleukin-1 beta production +is_a: GO:0045362 ! positive regulation of interleukin-1 biosynthetic process +is_a: GO:0050722 ! regulation of interleukin-1 beta biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050720 ! interleukin-1 beta biosynthetic process +relationship: positively_regulates GO:0050720 ! interleukin-1 beta biosynthetic process + +[Term] +id: GO:0050726 +name: positive regulation of interleukin-1 alpha biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] +synonym: "activation of interleukin-1 alpha biosynthetic process" NARROW [] +synonym: "positive regulation of interleukin-1 alpha anabolism" EXACT [] +synonym: "positive regulation of interleukin-1 alpha biosynthesis" EXACT [] +synonym: "positive regulation of interleukin-1 alpha formation" EXACT [] +synonym: "positive regulation of interleukin-1 alpha synthesis" EXACT [] +synonym: "stimulation of interleukin-1 alpha biosynthetic process" NARROW [] +synonym: "up regulation of interleukin-1 alpha biosynthetic process" EXACT [] +synonym: "up-regulation of interleukin-1 alpha biosynthetic process" EXACT [] +synonym: "upregulation of interleukin-1 alpha biosynthetic process" EXACT [] +is_a: GO:0032730 ! positive regulation of interleukin-1 alpha production +is_a: GO:0045362 ! positive regulation of interleukin-1 biosynthetic process +is_a: GO:0050721 ! regulation of interleukin-1 alpha biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050719 ! interleukin-1 alpha biosynthetic process +relationship: positively_regulates GO:0050719 ! interleukin-1 alpha biosynthetic process + +[Term] +id: GO:0050727 +name: regulation of inflammatory response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai] +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006954 ! inflammatory response +relationship: regulates GO:0006954 ! inflammatory response + +[Term] +id: GO:0050728 +name: negative regulation of inflammatory response +namespace: biological_process +alt_id: GO:0030236 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai] +synonym: "anti-inflammatory response" EXACT [] +synonym: "down regulation of inflammatory response" EXACT [] +synonym: "down-regulation of inflammatory response" EXACT [] +synonym: "downregulation of inflammatory response" EXACT [] +synonym: "inhibition of inflammatory response" NARROW [] +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006954 ! inflammatory response +relationship: negatively_regulates GO:0006954 ! inflammatory response + +[Term] +id: GO:0050729 +name: positive regulation of inflammatory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai] +synonym: "activation of inflammatory response" NARROW [] +synonym: "stimulation of inflammatory response" NARROW [] +synonym: "up regulation of inflammatory response" EXACT [] +synonym: "up-regulation of inflammatory response" EXACT [] +synonym: "upregulation of inflammatory response" EXACT [] +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006954 ! inflammatory response +relationship: positively_regulates GO:0006954 ! inflammatory response + +[Term] +id: GO:0050730 +name: regulation of peptidyl-tyrosine phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] +is_a: GO:0001932 ! regulation of protein phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018108 ! peptidyl-tyrosine phosphorylation +relationship: regulates GO:0018108 ! peptidyl-tyrosine phosphorylation + +[Term] +id: GO:0050731 +name: positive regulation of peptidyl-tyrosine phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] +synonym: "activation of peptidyl-tyrosine phosphorylation" NARROW [] +synonym: "stimulation of peptidyl-tyrosine phosphorylation" NARROW [] +synonym: "up regulation of peptidyl-tyrosine phosphorylation" EXACT [] +synonym: "up-regulation of peptidyl-tyrosine phosphorylation" EXACT [] +synonym: "upregulation of peptidyl-tyrosine phosphorylation" EXACT [] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation +relationship: positively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation + +[Term] +id: GO:0050732 +name: negative regulation of peptidyl-tyrosine phosphorylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] +synonym: "down regulation of peptidyl-tyrosine phosphorylation" EXACT [] +synonym: "down-regulation of peptidyl-tyrosine phosphorylation" EXACT [] +synonym: "downregulation of peptidyl-tyrosine phosphorylation" EXACT [] +synonym: "inhibition of peptidyl-tyrosine phosphorylation" NARROW [] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation +relationship: negatively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation + +[Term] +id: GO:0050733 +name: RS domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing." [PMID:11684676, PMID:12215544] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0050734 +name: hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule." [GOC:ai] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0050735 +name: N-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0016410 ! N-acyltransferase activity +is_a: GO:0016420 ! malonyltransferase activity + +[Term] +id: GO:0050736 +name: O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0016420 ! malonyltransferase activity + +[Term] +id: GO:0050737 +name: O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] +is_a: GO:0008374 ! O-acyltransferase activity +is_a: GO:0050734 ! hydroxycinnamoyltransferase activity + +[Term] +id: GO:0050738 +name: fructosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0050739 +name: peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium +namespace: biological_process +def: "The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium." [RESID:AA0348] +xref: RESID:AA0348 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018206 ! peptidyl-methionine modification +is_a: GO:0018211 ! peptidyl-tryptophan modification +is_a: GO:0018212 ! peptidyl-tyrosine modification + +[Term] +id: GO:0050740 +name: protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine +namespace: biological_process +def: "The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine." [RESID:AA0349] +xref: RESID:AA0349 +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0050741 +name: protein-FMN linkage via O3-riboflavin phosphoryl-L-serine +namespace: biological_process +def: "The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine." [RESID:AA0350] +xref: RESID:AA0350 +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0050742 +name: protein-FMN linkage via S-(4a-FMN)-L-cysteine +namespace: biological_process +def: "The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine." [RESID:AA0351] +xref: RESID:AA0351 +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0050743 +name: protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine +namespace: biological_process +def: "The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine." [PMID:8611516, RESID:AA0352] +xref: RESID:AA0352 +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0050744 +name: protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine +namespace: biological_process +def: "The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine." [RESID:AA0353] +xref: RESID:AA0353 +is_a: GO:0018309 ! protein-FMN linkage + +[Term] +id: GO:0050745 +name: peptide cross-linking via L-cysteinyl-5-imidazolinone glycine +namespace: biological_process +def: "The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water." [RESID:AA0188] +xref: RESID:AA0188 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine + +[Term] +id: GO:0050746 +name: regulation of lipoprotein metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:ai] +synonym: "regulation of lipoprotein metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042157 ! lipoprotein metabolic process +relationship: regulates GO:0042157 ! lipoprotein metabolic process + +[Term] +id: GO:0050747 +name: positive regulation of lipoprotein metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:ai] +synonym: "activation of lipoprotein metabolic process" NARROW [] +synonym: "positive regulation of lipoprotein metabolism" EXACT [] +synonym: "stimulation of lipoprotein metabolic process" NARROW [] +synonym: "up regulation of lipoprotein metabolic process" EXACT [] +synonym: "up-regulation of lipoprotein metabolic process" EXACT [] +synonym: "upregulation of lipoprotein metabolic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0050746 ! regulation of lipoprotein metabolic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042157 ! lipoprotein metabolic process +relationship: positively_regulates GO:0042157 ! lipoprotein metabolic process + +[Term] +id: GO:0050748 +name: negative regulation of lipoprotein metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids." [GOC:ai] +synonym: "down regulation of lipoprotein metabolic process" EXACT [] +synonym: "down-regulation of lipoprotein metabolic process" EXACT [] +synonym: "downregulation of lipoprotein metabolic process" EXACT [] +synonym: "inhibition of lipoprotein metabolic process" NARROW [] +synonym: "negative regulation of lipoprotein metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0050746 ! regulation of lipoprotein metabolic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042157 ! lipoprotein metabolic process +relationship: negatively_regulates GO:0042157 ! lipoprotein metabolic process + +[Term] +id: GO:0050749 +name: obsolete apolipoprotein E receptor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively with an apolipoprotein E receptor." [GOC:ai] +comment: This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid). +synonym: "apolipoprotein E receptor binding" EXACT [] +is_obsolete: true +replaced_by: GO:0070326 + +[Term] +id: GO:0050750 +name: low-density lipoprotein particle receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a low-density lipoprotein receptor." [GOC:ai] +synonym: "LDL receptor binding" EXACT [] +synonym: "low-density lipoprotein receptor binding" EXACT [GOC:dph] +is_a: GO:0070325 ! lipoprotein particle receptor binding + +[Term] +id: GO:0050751 +name: fractalkine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1." [http://www.copewithcytokines.de] +synonym: "ABCD-3 biosynthesis" EXACT [] +synonym: "ABCD-3 biosynthetic process" EXACT [] +synonym: "CX3C membrane-anchored chemokine biosynthesis" EXACT [] +synonym: "CX3C membrane-anchored chemokine biosynthetic process" EXACT [] +synonym: "CX3CL1 biosynthesis" EXACT [] +synonym: "CX3CL1 biosynthetic process" EXACT [] +synonym: "fractalkine anabolism" EXACT [] +synonym: "fractalkine biosynthesis" EXACT [] +synonym: "fractalkine formation" EXACT [] +synonym: "fractalkine synthesis" EXACT [] +synonym: "neurotactin biosynthesis" EXACT [] +synonym: "neurotactin biosynthetic process" EXACT [] +is_a: GO:0042033 ! chemokine biosynthetic process +is_a: GO:0050756 ! fractalkine metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0032603 ! fractalkine production + +[Term] +id: GO:0050752 +name: regulation of fractalkine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] +synonym: "regulation of CX3CL1 biosynthesis" EXACT [] +synonym: "regulation of CX3CL1 biosynthetic process" EXACT [] +synonym: "regulation of fractalkine anabolism" EXACT [] +synonym: "regulation of fractalkine biosynthesis" EXACT [] +synonym: "regulation of fractalkine formation" EXACT [] +synonym: "regulation of fractalkine synthesis" EXACT [] +synonym: "regulation of neurotactin biosynthesis" EXACT [] +synonym: "regulation of neurotactin biosynthetic process" EXACT [] +is_a: GO:0032644 ! regulation of fractalkine production +is_a: GO:0045073 ! regulation of chemokine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050751 ! fractalkine biosynthetic process +relationship: regulates GO:0050751 ! fractalkine biosynthetic process + +[Term] +id: GO:0050753 +name: negative regulation of fractalkine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] +synonym: "down regulation of fractalkine biosynthetic process" EXACT [] +synonym: "down-regulation of fractalkine biosynthetic process" EXACT [] +synonym: "downregulation of fractalkine biosynthetic process" EXACT [] +synonym: "inhibition of fractalkine biosynthetic process" NARROW [] +synonym: "negative regulation of CX3CL1 biosynthesis" EXACT [] +synonym: "negative regulation of CX3CL1 biosynthetic process" EXACT [] +synonym: "negative regulation of fractalkine anabolism" EXACT [] +synonym: "negative regulation of fractalkine biosynthesis" EXACT [] +synonym: "negative regulation of fractalkine formation" EXACT [] +synonym: "negative regulation of fractalkine synthesis" EXACT [] +synonym: "negative regulation of neurotactin biosynthesis" EXACT [] +synonym: "negative regulation of neurotactin biosynthetic process" EXACT [] +is_a: GO:0032684 ! negative regulation of fractalkine production +is_a: GO:0045079 ! negative regulation of chemokine biosynthetic process +is_a: GO:0050752 ! regulation of fractalkine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050751 ! fractalkine biosynthetic process +relationship: negatively_regulates GO:0050751 ! fractalkine biosynthetic process + +[Term] +id: GO:0050754 +name: positive regulation of fractalkine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] +synonym: "activation of fractalkine biosynthetic process" NARROW [] +synonym: "positive regulation of CX3CL1 biosynthesis" EXACT [] +synonym: "positive regulation of CX3CL1 biosynthetic process" EXACT [] +synonym: "positive regulation of fractalkine anabolism" EXACT [] +synonym: "positive regulation of fractalkine biosynthesis" EXACT [] +synonym: "positive regulation of fractalkine formation" EXACT [] +synonym: "positive regulation of fractalkine synthesis" EXACT [] +synonym: "positive regulation of neurotactin biosynthesis" EXACT [] +synonym: "positive regulation of neurotactin biosynthetic process" EXACT [] +synonym: "stimulation of fractalkine biosynthetic process" NARROW [] +synonym: "up regulation of fractalkine biosynthetic process" EXACT [] +synonym: "up-regulation of fractalkine biosynthetic process" EXACT [] +synonym: "upregulation of fractalkine biosynthetic process" EXACT [] +is_a: GO:0032724 ! positive regulation of fractalkine production +is_a: GO:0045080 ! positive regulation of chemokine biosynthetic process +is_a: GO:0050752 ! regulation of fractalkine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050751 ! fractalkine biosynthetic process +relationship: positively_regulates GO:0050751 ! fractalkine biosynthetic process + +[Term] +id: GO:0050755 +name: chemokine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, ISBN:0198506732, PMID:12183377, Wikipedia:Chemokine] +synonym: "chemokine metabolism" EXACT [] +is_a: GO:0042107 ! cytokine metabolic process + +[Term] +id: GO:0050756 +name: fractalkine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1." [http://www.copewithcytokines.de] +synonym: "ABCD-3 metabolic process" EXACT [] +synonym: "ABCD-3 metabolism" EXACT [] +synonym: "CX3C membrane-anchored chemokine metabolic process" EXACT [] +synonym: "CX3C membrane-anchored chemokine metabolism" EXACT [] +synonym: "CX3CL1 metabolic process" EXACT [] +synonym: "CX3CL1 metabolism" EXACT [] +synonym: "fractalkine metabolism" EXACT [] +synonym: "neurotactin metabolic process" EXACT [] +synonym: "neurotactin metabolism" EXACT [] +is_a: GO:0050755 ! chemokine metabolic process + +[Term] +id: GO:0050757 +name: thymidylate synthase biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP." [EC:2.1.1.45] +synonym: "thymidylate synthase anabolism" EXACT [] +synonym: "thymidylate synthase biosynthesis" EXACT [] +synonym: "thymidylate synthase formation" EXACT [] +synonym: "thymidylate synthase synthesis" EXACT [] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:0019538 ! protein metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0050758 +name: regulation of thymidylate synthase biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase." [GOC:ai] +synonym: "regulation of thymidylate synthase anabolism" EXACT [] +synonym: "regulation of thymidylate synthase biosynthesis" EXACT [] +synonym: "regulation of thymidylate synthase formation" EXACT [] +synonym: "regulation of thymidylate synthase synthesis" EXACT [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050757 ! thymidylate synthase biosynthetic process +relationship: regulates GO:0050757 ! thymidylate synthase biosynthetic process + +[Term] +id: GO:0050759 +name: positive regulation of thymidylate synthase biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase." [GOC:ai] +synonym: "activation of thymidylate synthase biosynthetic process" NARROW [] +synonym: "positive regulation of thymidylate synthase anabolism" EXACT [] +synonym: "positive regulation of thymidylate synthase biosynthesis" EXACT [] +synonym: "positive regulation of thymidylate synthase formation" EXACT [] +synonym: "positive regulation of thymidylate synthase synthesis" EXACT [] +synonym: "stimulation of thymidylate synthase biosynthetic process" NARROW [] +synonym: "up regulation of thymidylate synthase biosynthetic process" EXACT [] +synonym: "up-regulation of thymidylate synthase biosynthetic process" EXACT [] +synonym: "upregulation of thymidylate synthase biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0050758 ! regulation of thymidylate synthase biosynthetic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050757 ! thymidylate synthase biosynthetic process +relationship: positively_regulates GO:0050757 ! thymidylate synthase biosynthetic process + +[Term] +id: GO:0050760 +name: negative regulation of thymidylate synthase biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase." [GOC:ai] +synonym: "down regulation of thymidylate synthase biosynthetic process" EXACT [] +synonym: "down-regulation of thymidylate synthase biosynthetic process" EXACT [] +synonym: "downregulation of thymidylate synthase biosynthetic process" EXACT [] +synonym: "inhibition of thymidylate synthase biosynthetic process" NARROW [] +synonym: "negative regulation of thymidylate synthase anabolism" EXACT [] +synonym: "negative regulation of thymidylate synthase biosynthesis" EXACT [] +synonym: "negative regulation of thymidylate synthase formation" EXACT [] +synonym: "negative regulation of thymidylate synthase synthesis" EXACT [] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0050758 ! regulation of thymidylate synthase biosynthetic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050757 ! thymidylate synthase biosynthetic process +relationship: negatively_regulates GO:0050757 ! thymidylate synthase biosynthetic process + +[Term] +id: GO:0050761 +name: depsipeptide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively." [GOC:go_curators] +subset: goslim_pir +synonym: "depsipeptide metabolism" EXACT [] +is_a: GO:0006518 ! peptide metabolic process + +[Term] +id: GO:0050762 +name: depsipeptide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively." [GOC:go_curators] +synonym: "depsipeptide breakdown" EXACT [] +synonym: "depsipeptide catabolism" EXACT [] +synonym: "depsipeptide degradation" EXACT [] +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0050761 ! depsipeptide metabolic process + +[Term] +id: GO:0050763 +name: depsipeptide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively." [GOC:go_curators] +synonym: "depsipeptide anabolism" EXACT [] +synonym: "depsipeptide biosynthesis" EXACT [] +synonym: "depsipeptide formation" EXACT [] +synonym: "depsipeptide synthesis" EXACT [] +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0050761 ! depsipeptide metabolic process + +[Term] +id: GO:0050764 +name: regulation of phagocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006909 ! phagocytosis +relationship: regulates GO:0006909 ! phagocytosis +property_value: RO:0002161 NCBITaxon:147537 + +[Term] +id: GO:0050765 +name: negative regulation of phagocytosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." [GOC:ai] +synonym: "down regulation of phagocytosis" EXACT [] +synonym: "down-regulation of phagocytosis" EXACT [] +synonym: "downregulation of phagocytosis" EXACT [] +synonym: "inhibition of phagocytosis" NARROW [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0050764 ! regulation of phagocytosis +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006909 ! phagocytosis +relationship: negatively_regulates GO:0006909 ! phagocytosis + +[Term] +id: GO:0050766 +name: positive regulation of phagocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai] +synonym: "activation of phagocytosis" NARROW [] +synonym: "stimulation of phagocytosis" NARROW [] +synonym: "up regulation of phagocytosis" EXACT [] +synonym: "up-regulation of phagocytosis" EXACT [] +synonym: "upregulation of phagocytosis" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0050764 ! regulation of phagocytosis +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006909 ! phagocytosis +relationship: positively_regulates GO:0006909 ! phagocytosis + +[Term] +id: GO:0050767 +name: regulation of neurogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022008 ! neurogenesis +relationship: part_of GO:0048699 ! generation of neurons +relationship: regulates GO:0022008 ! neurogenesis + +[Term] +id: GO:0050768 +name: negative regulation of neurogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] +synonym: "down regulation of neurogenesis" EXACT [] +synonym: "down-regulation of neurogenesis" EXACT [] +synonym: "downregulation of neurogenesis" EXACT [] +synonym: "inhibition of neurogenesis" NARROW [] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0050767 ! regulation of neurogenesis +is_a: GO:0051961 ! negative regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022008 ! neurogenesis +relationship: negatively_regulates GO:0022008 ! neurogenesis + +[Term] +id: GO:0050769 +name: positive regulation of neurogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] +synonym: "activation of neurogenesis" NARROW [] +synonym: "stimulation of neurogenesis" NARROW [] +synonym: "up regulation of neurogenesis" EXACT [] +synonym: "up-regulation of neurogenesis" EXACT [] +synonym: "upregulation of neurogenesis" EXACT [] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0050767 ! regulation of neurogenesis +is_a: GO:0051962 ! positive regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022008 ! neurogenesis +relationship: positively_regulates GO:0022008 ! neurogenesis + +[Term] +id: GO:0050770 +name: regulation of axonogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." [GOC:ai] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0010975 ! regulation of neuron projection development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007409 ! axonogenesis +relationship: regulates GO:0007409 ! axonogenesis + +[Term] +id: GO:0050771 +name: negative regulation of axonogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." [GOC:ai] +synonym: "down regulation of axonogenesis" EXACT [] +synonym: "down-regulation of axonogenesis" EXACT [] +synonym: "downregulation of axonogenesis" EXACT [] +synonym: "inhibition of axonogenesis" NARROW [] +is_a: GO:0010771 ! negative regulation of cell morphogenesis involved in differentiation +is_a: GO:0010977 ! negative regulation of neuron projection development +is_a: GO:0050770 ! regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007409 ! axonogenesis +relationship: negatively_regulates GO:0007409 ! axonogenesis + +[Term] +id: GO:0050772 +name: positive regulation of axonogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axonogenesis." [GOC:ai] +synonym: "activation of axonogenesis" NARROW [] +synonym: "stimulation of axonogenesis" NARROW [] +synonym: "up regulation of axonogenesis" EXACT [] +synonym: "up-regulation of axonogenesis" EXACT [] +synonym: "upregulation of axonogenesis" EXACT [] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0010976 ! positive regulation of neuron projection development +is_a: GO:0050770 ! regulation of axonogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007409 ! axonogenesis +relationship: positively_regulates GO:0007409 ! axonogenesis + +[Term] +id: GO:0050773 +name: regulation of dendrite development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendrite development." [GOC:ai] +is_a: GO:0010975 ! regulation of neuron projection development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016358 ! dendrite development +relationship: regulates GO:0016358 ! dendrite development + +[Term] +id: GO:0050774 +name: negative regulation of dendrite morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] +synonym: "down regulation of dendrite morphogenesis" EXACT [] +synonym: "down-regulation of dendrite morphogenesis" EXACT [] +synonym: "downregulation of dendrite morphogenesis" EXACT [] +synonym: "inhibition of dendrite morphogenesis" NARROW [] +is_a: GO:0010771 ! negative regulation of cell morphogenesis involved in differentiation +is_a: GO:0048814 ! regulation of dendrite morphogenesis +is_a: GO:2000171 ! negative regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048813 ! dendrite morphogenesis +relationship: negatively_regulates GO:0048813 ! dendrite morphogenesis + +[Term] +id: GO:0050775 +name: positive regulation of dendrite morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] +synonym: "activation of dendrite morphogenesis" NARROW [] +synonym: "stimulation of dendrite morphogenesis" NARROW [] +synonym: "up regulation of dendrite morphogenesis" EXACT [] +synonym: "up-regulation of dendrite morphogenesis" EXACT [] +synonym: "upregulation of dendrite morphogenesis" EXACT [] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0048814 ! regulation of dendrite morphogenesis +is_a: GO:1900006 ! positive regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048813 ! dendrite morphogenesis +relationship: positively_regulates GO:0048813 ! dendrite morphogenesis + +[Term] +id: GO:0050776 +name: regulation of immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006955 ! immune response +relationship: regulates GO:0006955 ! immune response + +[Term] +id: GO:0050777 +name: negative regulation of immune response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] +synonym: "down regulation of immune response" EXACT [] +synonym: "down-regulation of immune response" EXACT [] +synonym: "downregulation of immune response" EXACT [] +synonym: "inhibition of immune response" NARROW [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006955 ! immune response +relationship: negatively_regulates GO:0006955 ! immune response + +[Term] +id: GO:0050778 +name: positive regulation of immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] +synonym: "stimulation of immune response" NARROW [] +synonym: "up regulation of immune response" EXACT [] +synonym: "up-regulation of immune response" EXACT [] +synonym: "upregulation of immune response" EXACT [] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006955 ! immune response +relationship: positively_regulates GO:0006955 ! immune response + +[Term] +id: GO:0050779 +name: RNA destabilization +namespace: biological_process +def: "Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes." [GOC:ai] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0043487 ! regulation of RNA stability +is_a: GO:0051254 ! positive regulation of RNA metabolic process +relationship: positively_regulates GO:0006401 ! RNA catabolic process + +[Term] +id: GO:0050780 +name: dopamine receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a dopamine receptor." [GOC:ai] +is_a: GO:0001664 ! G protein-coupled receptor binding + +[Term] +id: GO:0050781 +name: ortho-trichlorophenol reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl." [GOC:ai, PMID:12697029] +synonym: "2,4,6-TCP reductive dehalogenase activity" EXACT [] +synonym: "2,4,6-trichlorophenol reductive dehalogenase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0050782 +name: galactose uniporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in)." [GOC:ai, TC:2.A.1.1.6] +synonym: "galactose, glucose uniporter activity" BROAD [] +is_a: GO:0005354 ! galactose transmembrane transporter activity +is_a: GO:0008516 ! hexose uniporter activity + +[Term] +id: GO:0050783 +name: cocaine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic." [ISBN:0198506732] +synonym: "cocaine metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046448 ! tropane alkaloid metabolic process + +[Term] +id: GO:0050784 +name: cocaine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic." [ISBN:0198506732] +synonym: "cocaine breakdown" EXACT [] +synonym: "cocaine catabolism" EXACT [] +synonym: "cocaine degradation" EXACT [] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0050783 ! cocaine metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process + +[Term] +id: GO:0050785 +name: advanced glycation end-product receptor activity +namespace: molecular_function +def: "Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins)." [GOC:signaling, PMID:12453678, PMID:12707408, PMID:7592757, PMID:9224812, Wikipedia:RAGE_(receptor)] +synonym: "AGE receptor activity" EXACT [PMID:21590515] +synonym: "RAGE activity" EXACT [PMID:21590515] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0050786 +name: RAGE receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products." [GOC:ai] +synonym: "advanced glycation end-product receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0050787 +name: detoxification of mercury ion +namespace: biological_process +def: "Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])." [PMID:10774920] +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:0046689 ! response to mercury ion + +[Term] +id: GO:0050788 +name: sequestering of mercury +namespace: biological_process +def: "The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system." [PMID:10774920] +synonym: "mercuric ion (Hg2+) sequestering" EXACT [] +synonym: "mercuric ion (Hg2+) sequestration" EXACT [] +synonym: "mercury (Hg) ion sequestering" EXACT [] +synonym: "mercury (Hg) ion sequestration" EXACT [] +synonym: "mercury (Hg2+) ion retention" EXACT [] +synonym: "mercury (Hg2+) ion storage" EXACT [] +synonym: "retention of mercury (Hg2+) ion" EXACT [] +synonym: "sequestering of mercuric ion (Hg2+)" EXACT [] +synonym: "sequestering of mercury (Hg) ion" EXACT [] +synonym: "sequestration of mercuric ion (Hg2+)" EXACT [] +synonym: "sequestration of mercury (Hg) ion" EXACT [] +synonym: "storage of mercury (Hg2+) ion" EXACT [] +is_a: GO:0051238 ! sequestering of metal ion +relationship: part_of GO:0050787 ! detoxification of mercury ion + +[Term] +id: GO:0050789 +name: regulation of biological process +namespace: biological_process +alt_id: GO:0050791 +def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] +subset: gocheck_do_not_annotate +subset: goslim_aspergillus +subset: goslim_candida +subset: goslim_pir +synonym: "regulation of physiological process" EXACT [] +is_a: GO:0065007 ! biological regulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008150 ! biological_process +relationship: regulates GO:0008150 ! biological_process + +[Term] +id: GO:0050790 +name: regulation of catalytic activity +namespace: biological_process +alt_id: GO:0048552 +def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] +subset: goslim_chembl +synonym: "regulation of enzyme activity" EXACT [] +synonym: "regulation of metalloenzyme activity" NARROW [] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003824 ! catalytic activity +relationship: regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0050792 +name: regulation of viral process +namespace: biological_process +def: "Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts." [GOC:go_curators, GOC:tb] +synonym: "regulation of viral process" BROAD [] +synonym: "regulation of viral reproduction" NARROW [GOC:bf, GOC:jl] +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016032 ! viral process +relationship: regulates GO:0016032 ! viral process + +[Term] +id: GO:0050793 +name: regulation of developmental process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032502 ! developmental process +relationship: regulates GO:0032502 ! developmental process + +[Term] +id: GO:0050794 +name: regulation of cellular process +namespace: biological_process +alt_id: GO:0051244 +def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] +synonym: "regulation of cellular physiological process" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0009987 ! cellular process +relationship: regulates GO:0009987 ! cellular process + +[Term] +id: GO:0050795 +name: regulation of behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr] +synonym: "regulation of behaviour" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007610 ! behavior +relationship: regulates GO:0007610 ! behavior + +[Term] +id: GO:0050796 +name: regulation of insulin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030073 ! insulin secretion +relationship: regulates GO:0030073 ! insulin secretion + +[Term] +id: GO:0050797 +name: thymidylate synthase (FAD) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+." [EC:2.1.1.148] +synonym: "5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.148] +synonym: "FDTS activity" EXACT [EC:2.1.1.148] +synonym: "flavin dependent thymidylate synthase activity" EXACT [EC:2.1.1.148] +synonym: "Thy1 activity" EXACT [] +synonym: "ThyX activity" EXACT [] +xref: EC:2.1.1.148 +xref: KEGG_REACTION:R06613 +xref: MetaCyc:RXN-8850 +xref: RHEA:29043 +is_a: GO:0042083 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity + +[Term] +id: GO:0050798 +name: activated T cell proliferation +namespace: biological_process +def: "The expansion of a T cell population following activation by an antigenic stimulus." [GOC:add, GOC:dph] +comment: Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells. +synonym: "activated T lymphocyte proliferation" EXACT [] +synonym: "activated T-cell proliferation" EXACT [] +synonym: "activated T-lymphocyte proliferation" EXACT [] +synonym: "proliferation of activated T cells" EXACT [GOC:mah] +is_a: GO:0042098 ! T cell proliferation + +[Term] +id: GO:0050799 +name: cocaine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic." [GOC:ai] +synonym: "cocaine anabolism" EXACT [] +synonym: "cocaine biosynthesis" EXACT [] +synonym: "cocaine formation" EXACT [] +synonym: "cocaine synthesis" EXACT [] +is_a: GO:0009710 ! tropane alkaloid biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0050783 ! cocaine metabolic process + +[Term] +id: GO:0050800 +name: obsolete hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance." [EC:3.6.5.-, GOC:ai] +comment: This term was made obsolete because it represents both process and function information. +synonym: "hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement" EXACT [] +is_obsolete: true +consider: GO:0003924 +consider: GO:0006810 + +[Term] +id: GO:0050801 +name: ion homeostasis +namespace: biological_process +alt_id: GO:2000021 +def: "Any process involved in the maintenance of an internal steady state of ions within an organism or cell." [GOC:ai] +synonym: "electrolyte homeostasis" RELATED [] +synonym: "negative regulation of crystal formation" RELATED [] +synonym: "regulation of ion homeostasis" RELATED [] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0050802 +name: circadian sleep/wake cycle, sleep +namespace: biological_process +def: "The part of the circadian sleep/wake cycle where the organism is asleep." [GOC:ai] +is_a: GO:0022410 ! circadian sleep/wake cycle process +is_a: GO:0030431 ! sleep +intersection_of: GO:0030431 ! sleep +intersection_of: part_of GO:0042745 ! circadian sleep/wake cycle + +[Term] +id: GO:0050803 +name: regulation of synapse structure or activity +namespace: biological_process +def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0050804 +name: modulation of chemical synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai] +subset: goslim_synapse +synonym: "modulation of synaptic transmission" BROAD [] +synonym: "regulation of chemical synaptic transmission" EXACT [] +synonym: "regulation of synaptic transmission" EXACT [] +is_a: GO:0099177 ! regulation of trans-synaptic signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007268 ! chemical synaptic transmission +relationship: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0050805 +name: negative regulation of synaptic transmission +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] +synonym: "down regulation of synaptic transmission" EXACT [] +synonym: "down-regulation of synaptic transmission" EXACT [] +synonym: "downregulation of synaptic transmission" EXACT [] +synonym: "inhibition of synaptic transmission" NARROW [] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007268 ! chemical synaptic transmission +relationship: negatively_regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0050806 +name: positive regulation of synaptic transmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] +synonym: "activation of synaptic transmission" NARROW [] +synonym: "stimulation of synaptic transmission" NARROW [] +synonym: "up regulation of synaptic transmission" EXACT [] +synonym: "up-regulation of synaptic transmission" EXACT [] +synonym: "upregulation of synaptic transmission" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007268 ! chemical synaptic transmission +relationship: positively_regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0050807 +name: regulation of synapse organization +namespace: biological_process +def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_synapse +synonym: "regulation of synapse organisation" EXACT [GOC:mah] +synonym: "regulation of synapse organization and biogenesis" RELATED [GOC:mah] +synonym: "regulation of synapse structure" EXACT [] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050808 ! synapse organization +relationship: part_of GO:0050803 ! regulation of synapse structure or activity +relationship: regulates GO:0050808 ! synapse organization + +[Term] +id: GO:0050808 +name: synapse organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr] +subset: goslim_drosophila +subset: goslim_synapse +synonym: "synapse development" RELATED [GOC:aruk] +synonym: "synapse morphogenesis" RELATED [GOC:BHF] +synonym: "synapse organisation" EXACT [] +synonym: "synapse organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0034330 ! cell junction organization + +[Term] +id: GO:0050809 +name: diazepam binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium." [ISBN:0198506732] +synonym: "diazepam binding inhibitor activity" RELATED [] +synonym: "Valium binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0050810 +name: regulation of steroid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] +synonym: "regulation of steroid anabolism" EXACT [] +synonym: "regulation of steroid biosynthesis" EXACT [] +synonym: "regulation of steroid formation" EXACT [] +synonym: "regulation of steroid synthesis" EXACT [] +synonym: "regulation of steroidogenesis" EXACT [] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006694 ! steroid biosynthetic process +relationship: regulates GO:0006694 ! steroid biosynthetic process + +[Term] +id: GO:0050811 +name: GABA receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor." [GOC:ai] +synonym: "4-aminobutanoate receptor binding" EXACT [] +synonym: "4-aminobutyrate receptor binding" EXACT [] +synonym: "diazepam binding inhibitor activity" RELATED [] +synonym: "gamma-aminobutyric acid receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0050812 +name: regulation of acyl-CoA biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA." [GOC:ai] +synonym: "regulation of acyl-CoA anabolism" EXACT [] +synonym: "regulation of acyl-CoA biosynthesis" EXACT [] +synonym: "regulation of acyl-CoA formation" EXACT [] +synonym: "regulation of acyl-CoA synthesis" EXACT [] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071616 ! acyl-CoA biosynthetic process +relationship: regulates GO:0071616 ! acyl-CoA biosynthetic process + +[Term] +id: GO:0050813 +name: epothilone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer." [ISBN:0198506732] +synonym: "epothilone metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0033067 ! macrolide metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0050814 +name: epothilone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer." [GOC:ai] +synonym: "epothilone anabolism" EXACT [] +synonym: "epothilone biosynthesis" EXACT [] +synonym: "epothilone formation" EXACT [] +synonym: "epothilone synthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0033068 ! macrolide biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0050813 ! epothilone metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0050815 +name: phosphoserine residue binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphorylated serine residue within a protein." [GOC:ai] +synonym: "phosphoserine binding" RELATED [] +is_a: GO:0045309 ! protein phosphorylated amino acid binding + +[Term] +id: GO:0050816 +name: phosphothreonine residue binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein." [GOC:ai] +synonym: "phosphothreonine binding" RELATED [] +is_a: GO:0045309 ! protein phosphorylated amino acid binding + +[Term] +id: GO:0050817 +name: coagulation +namespace: biological_process +def: "The process in which a fluid solution, or part of it, changes into a solid or semisolid mass." [ISBN:0198506732] +subset: goslim_pir +synonym: "clotting" EXACT [] +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0050818 +name: regulation of coagulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass." [GOC:ai] +synonym: "regulation of clotting" EXACT [] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050817 ! coagulation +relationship: regulates GO:0050817 ! coagulation + +[Term] +id: GO:0050819 +name: negative regulation of coagulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation." [GOC:ai] +synonym: "anticoagulant activity" RELATED [] +synonym: "down regulation of coagulation" EXACT [] +synonym: "down-regulation of coagulation" EXACT [] +synonym: "downregulation of coagulation" EXACT [] +synonym: "inhibition of coagulation" NARROW [] +synonym: "negative regulation of clotting" EXACT [] +is_a: GO:0050818 ! regulation of coagulation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050817 ! coagulation +relationship: negatively_regulates GO:0050817 ! coagulation + +[Term] +id: GO:0050820 +name: positive regulation of coagulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of coagulation." [GOC:ai] +synonym: "activation of coagulation" NARROW [] +synonym: "positive regulation of clotting" EXACT [] +synonym: "stimulation of coagulation" NARROW [] +synonym: "up regulation of coagulation" EXACT [] +synonym: "up-regulation of coagulation" EXACT [] +synonym: "upregulation of coagulation" EXACT [] +is_a: GO:0050818 ! regulation of coagulation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050817 ! coagulation +relationship: positively_regulates GO:0050817 ! coagulation + +[Term] +id: GO:0050821 +name: protein stabilization +namespace: biological_process +def: "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." [GOC:ai] +subset: goslim_chembl +synonym: "lysosomal protein stabilization" NARROW [] +synonym: "positive regulation of protein stability" EXACT [] +synonym: "protein sequestering" RELATED [] +synonym: "protein stabilisation" EXACT [GOC:ah] +synonym: "protein stabilization activity" RELATED [] +is_a: GO:0031647 ! regulation of protein stability + +[Term] +id: GO:0050822 +name: peptide stabilization +namespace: biological_process +def: "Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded." [GOC:ai] +synonym: "peptide stabilisation" EXACT [GOC:ah] +synonym: "peptide stabilization activity" RELATED [] +is_a: GO:0006518 ! peptide metabolic process + +[Term] +id: GO:0050823 +name: peptide antigen stabilization +namespace: biological_process +def: "Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded." [GOC:ai] +synonym: "peptide antigen stabilization activity" RELATED [] +is_a: GO:0050822 ! peptide stabilization +relationship: part_of GO:0048002 ! antigen processing and presentation of peptide antigen + +[Term] +id: GO:0050824 +name: obsolete water binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with water (H2O)." [GOC:ai] +comment: This term was obsoleted because water binding is non-specific. +is_obsolete: true + +[Term] +id: GO:0050825 +name: ice binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal." [GOC:curators] +synonym: "antifreeze activity" RELATED [] +synonym: "ice crystal binding" EXACT [] +synonym: "ice nucleation activity" RELATED [] +synonym: "ice nucleation inhibitor activity" RELATED [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0050826 +name: response to freezing +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius." [GOC:jl] +synonym: "antifreeze activity" RELATED [] +synonym: "ice nucleation inhibitor activity" RELATED [] +is_a: GO:0009409 ! response to cold + +[Term] +id: GO:0050828 +name: regulation of liquid surface tension +namespace: biological_process +def: "Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid." [ISBN:0198506732] +synonym: "regulation of surface tension of a liquid" EXACT [] +synonym: "surfactant activity" RELATED [] +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0050829 +name: defense response to Gram-negative bacterium +namespace: biological_process +def: "Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism." [GOC:ai] +synonym: "defence response to Gram-negative bacteria" EXACT [] +synonym: "defence response to Gram-negative bacterium" EXACT [] +synonym: "defense response to Gram-negative bacteria" EXACT [] +synonym: "Gram-negative antibacterial peptide activity" RELATED [] +is_a: GO:0042742 ! defense response to bacterium + +[Term] +id: GO:0050830 +name: defense response to Gram-positive bacterium +namespace: biological_process +def: "Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism." [GOC:ai] +synonym: "defence response to Gram-positive bacteria" EXACT [] +synonym: "defence response to Gram-positive bacterium" EXACT [] +synonym: "defense response to Gram-positive bacteria" EXACT [] +synonym: "Gram-positive antibacterial peptide activity" RELATED [] +is_a: GO:0042742 ! defense response to bacterium + +[Term] +id: GO:0050831 +name: male-specific defense response to bacterium +namespace: biological_process +def: "A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:ai] +synonym: "male-specific antibacterial peptide activity" RELATED [] +synonym: "male-specific defence response to bacteria" EXACT [] +synonym: "male-specific defence response to bacterium" EXACT [] +synonym: "male-specific defense response to bacteria" EXACT [] +is_a: GO:0042742 ! defense response to bacterium + +[Term] +id: GO:0050832 +name: defense response to fungus +namespace: biological_process +alt_id: GO:0009623 +alt_id: GO:0042831 +def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai] +synonym: "defence response to fungi" EXACT [] +synonym: "defence response to fungus" EXACT [] +synonym: "defense response to fungi" EXACT [] +synonym: "response to parasitic fungi" NARROW [] +synonym: "response to parasitic fungus" NARROW [] +is_a: GO:0009620 ! response to fungus +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0050833 +name: pyruvate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other." [GOC:ai] +synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" RELATED [] +xref: Reactome:R-HSA-372342 "MPC1:MPC2 cotransports PYR, H+ from cytosol to mitochondrial matrix" +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +relationship: part_of GO:1901475 ! pyruvate transmembrane transport + +[Term] +id: GO:0050834 +name: molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide +namespace: biological_process +def: "The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide." [RESID:AA0355] +xref: RESID:AA0355 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex + +[Term] +id: GO:0050835 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide." [RESID:AA0356] +xref: RESID:AA0356 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster +is_a: GO:0050843 ! S-adenosylmethionine catabolic process + +[Term] +id: GO:0050836 +name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide +namespace: biological_process +def: "The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide." [RESID:AA0357] +xref: RESID:AA0357 +is_a: GO:0018195 ! peptidyl-arginine modification +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018283 ! iron incorporation into metallo-sulfur cluster + +[Term] +id: GO:0050837 +name: peptide cross-linking via L-cysteinyl-L-selenocysteine +namespace: biological_process +def: "The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P." [RESID:AA0358] +xref: RESID:AA0358 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0050844 ! peptidyl-selenocysteine modification + +[Term] +id: GO:0050838 +name: peptidyl-5-hydroxy-L-lysine trimethylation +namespace: biological_process +def: "The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine." [RESID:AA0359] +xref: RESID:AA0359 +is_a: GO:0018022 ! peptidyl-lysine methylation + +[Term] +id: GO:0050839 +name: cell adhesion molecule binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cell adhesion molecule." [GOC:ai] +synonym: "adhesive extracellular matrix constituent" RELATED [] +synonym: "CAM binding" EXACT [] +synonym: "cell adhesion molecule activity" RELATED [] +synonym: "cell adhesion receptor activity" RELATED [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0050840 +name: extracellular matrix binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a component of the extracellular matrix." [GOC:ai] +subset: goslim_chembl +subset: goslim_pir +synonym: "adhesive extracellular matrix constituent" RELATED [] +synonym: "extracellular matrix constituent binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0050841 +name: peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine +namespace: biological_process +def: "The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine." [RESID:AA0359] +synonym: "peptidyl trimethyl lysine hydroxylase activity" EXACT [] +synonym: "peptidyl-trimethyl-lysine hydroxylase activity" EXACT [] +xref: RESID:AA0359 +is_a: GO:0017185 ! peptidyl-lysine hydroxylation + +[Term] +id: GO:0050842 +name: copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide +namespace: biological_process +def: "The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide." [RESID:AA0355] +xref: RESID:AA0355 +is_a: GO:0018198 ! peptidyl-cysteine modification +is_a: GO:0018427 ! copper incorporation into metallo-sulfur cluster + +[Term] +id: GO:0050843 +name: S-adenosylmethionine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism." [GOC:ai] +synonym: "S-adenosyl methionine catabolic process" EXACT [] +synonym: "S-adenosyl methionine catabolism" EXACT [] +synonym: "S-adenosylmethionine breakdown" EXACT [] +synonym: "S-adenosylmethionine catabolism" EXACT [] +synonym: "S-adenosylmethionine degradation" EXACT [] +synonym: "SAM catabolic process" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046500 ! S-adenosylmethionine metabolic process +is_a: GO:1901575 ! organic substance catabolic process + +[Term] +id: GO:0050844 +name: peptidyl-selenocysteine modification +namespace: biological_process +def: "The modification of peptidyl-selenocysteine." [GOC:ai] +is_a: GO:0018193 ! peptidyl-amino acid modification + +[Term] +id: GO:0050845 +name: teichuronic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria." [ISBN:0815108893] +synonym: "teichuronic acid anabolism" EXACT [] +synonym: "teichuronic acid biosynthesis" EXACT [] +synonym: "teichuronic acid formation" EXACT [] +synonym: "teichuronic acid synthesis" EXACT [] +is_a: GO:0016053 ! organic acid biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process +is_a: GO:0050846 ! teichuronic acid metabolic process +relationship: part_of GO:0009273 ! peptidoglycan-based cell wall biogenesis + +[Term] +id: GO:0050846 +name: teichuronic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria." [ISBN:0815108893] +synonym: "teichuronic acid metabolism" EXACT [] +is_a: GO:0006082 ! organic acid metabolic process + +[Term] +id: GO:0050847 +name: progesterone receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a progesterone binding to its receptor." [GOC:ai, GOC:mah, PMID:14744870] +synonym: "progesterone receptor signalling pathway" EXACT [] +is_a: GO:0030518 ! intracellular steroid hormone receptor signaling pathway + +[Term] +id: GO:0050848 +name: regulation of calcium-mediated signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response." [GOC:ai] +synonym: "regulation of calcium-mediated signalling" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019722 ! calcium-mediated signaling +relationship: regulates GO:0019722 ! calcium-mediated signaling + +[Term] +id: GO:0050849 +name: negative regulation of calcium-mediated signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling." [GOC:ai, PMID:11696592] +synonym: "down regulation of calcium-mediated signaling" EXACT [] +synonym: "down-regulation of calcium-mediated signaling" EXACT [] +synonym: "downregulation of calcium-mediated signaling" EXACT [] +synonym: "inhibition of calcium-mediated signaling" NARROW [] +synonym: "negative regulation of calcium-mediated signalling" EXACT [] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019722 ! calcium-mediated signaling +relationship: negatively_regulates GO:0019722 ! calcium-mediated signaling + +[Term] +id: GO:0050850 +name: positive regulation of calcium-mediated signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling." [GOC:ai] +synonym: "activation of calcium-mediated signaling" NARROW [] +synonym: "positive regulation of calcium-mediated signalling" EXACT [] +synonym: "stimulation of calcium-mediated signaling" NARROW [] +synonym: "up regulation of calcium-mediated signaling" EXACT [] +synonym: "up-regulation of calcium-mediated signaling" EXACT [] +synonym: "upregulation of calcium-mediated signaling" EXACT [] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019722 ! calcium-mediated signaling +relationship: positively_regulates GO:0019722 ! calcium-mediated signaling + +[Term] +id: GO:0050851 +name: antigen receptor-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell." [GOC:add] +synonym: "antigen receptor-mediated signalling pathway" EXACT [] +is_a: GO:0002429 ! immune response-activating cell surface receptor signaling pathway + +[Term] +id: GO:0050852 +name: T cell receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell." [GOC:add] +synonym: "T lymphocyte receptor signaling pathway" EXACT [] +synonym: "T lymphocyte receptor signalling pathway" EXACT [] +synonym: "T-cell receptor signaling pathway" EXACT [] +synonym: "T-cell receptor signalling pathway" EXACT [] +synonym: "T-lymphocyte receptor signaling pathway" EXACT [] +synonym: "T-lymphocyte receptor signalling pathway" EXACT [] +synonym: "TCR signaling pathway" EXACT [] +is_a: GO:0050851 ! antigen receptor-mediated signaling pathway + +[Term] +id: GO:0050853 +name: B cell receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell." [GOC:add] +synonym: "B cell receptor signalling pathway" EXACT [] +synonym: "B lymphocyte receptor signaling pathway" EXACT [] +synonym: "B lymphocyte receptor signalling pathway" EXACT [] +synonym: "B-cell receptor signaling pathway" EXACT [] +synonym: "B-cell receptor signalling pathway" EXACT [] +synonym: "B-lymphocyte receptor signaling pathway" EXACT [] +synonym: "B-lymphocyte receptor signalling pathway" EXACT [] +is_a: GO:0050851 ! antigen receptor-mediated signaling pathway + +[Term] +id: GO:0050854 +name: regulation of antigen receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] +synonym: "regulation of antigen receptor mediated signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050851 ! antigen receptor-mediated signaling pathway +relationship: regulates GO:0050851 ! antigen receptor-mediated signaling pathway + +[Term] +id: GO:0050855 +name: regulation of B cell receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] +synonym: "regulation of B cell receptor signalling pathway" EXACT [] +synonym: "regulation of B lymphocyte receptor signaling pathway" EXACT [] +synonym: "regulation of B lymphocyte receptor signalling pathway" EXACT [] +synonym: "regulation of B-cell receptor signaling pathway" EXACT [] +synonym: "regulation of B-cell receptor signalling pathway" EXACT [] +synonym: "regulation of B-lymphocyte receptor signaling pathway" EXACT [] +synonym: "regulation of B-lymphocyte receptor signalling pathway" EXACT [] +is_a: GO:0050854 ! regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050853 ! B cell receptor signaling pathway +relationship: regulates GO:0050853 ! B cell receptor signaling pathway + +[Term] +id: GO:0050856 +name: regulation of T cell receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] +synonym: "regulation of T lymphocyte receptor signaling pathway" EXACT [] +synonym: "regulation of T lymphocyte receptor signalling pathway" EXACT [] +synonym: "regulation of T-cell receptor signaling pathway" EXACT [] +synonym: "regulation of T-cell receptor signalling pathway" EXACT [] +synonym: "regulation of T-lymphocyte receptor signaling pathway" EXACT [] +synonym: "regulation of T-lymphocyte receptor signalling pathway" EXACT [] +synonym: "regulation of TCR signaling pathway" EXACT [] +is_a: GO:0050854 ! regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050852 ! T cell receptor signaling pathway +relationship: regulates GO:0050852 ! T cell receptor signaling pathway + +[Term] +id: GO:0050857 +name: positive regulation of antigen receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] +synonym: "activation of antigen receptor-mediated signaling pathway" NARROW [] +synonym: "positive regulation of antigen receptor mediated signalling pathway" EXACT [] +synonym: "stimulation of antigen receptor-mediated signaling pathway" NARROW [] +synonym: "up regulation of antigen receptor-mediated signaling pathway" EXACT [] +synonym: "up-regulation of antigen receptor-mediated signaling pathway" EXACT [] +synonym: "upregulation of antigen receptor-mediated signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:0050854 ! regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050851 ! antigen receptor-mediated signaling pathway +relationship: positively_regulates GO:0050851 ! antigen receptor-mediated signaling pathway + +[Term] +id: GO:0050858 +name: negative regulation of antigen receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] +synonym: "down regulation of antigen receptor-mediated signaling pathway" EXACT [] +synonym: "down-regulation of antigen receptor-mediated signaling pathway" EXACT [] +synonym: "downregulation of antigen receptor-mediated signaling pathway" EXACT [] +synonym: "inhibition of antigen receptor-mediated signaling pathway" NARROW [] +synonym: "negative regulation of antigen receptor mediated signalling pathway" EXACT [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0050854 ! regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050851 ! antigen receptor-mediated signaling pathway +relationship: negatively_regulates GO:0050851 ! antigen receptor-mediated signaling pathway + +[Term] +id: GO:0050859 +name: negative regulation of B cell receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] +synonym: "down regulation of B cell receptor signaling pathway" EXACT [] +synonym: "down-regulation of B cell receptor signaling pathway" EXACT [] +synonym: "downregulation of B cell receptor signaling pathway" EXACT [] +synonym: "inhibition of B cell receptor signaling pathway" NARROW [] +synonym: "negative regulation of B cell receptor signalling pathway" EXACT [] +synonym: "negative regulation of B lymphocyte receptor signaling pathway" EXACT [] +synonym: "negative regulation of B lymphocyte receptor signalling pathway" EXACT [] +synonym: "negative regulation of B-cell receptor signaling pathway" EXACT [] +synonym: "negative regulation of B-cell receptor signalling pathway" EXACT [] +synonym: "negative regulation of B-lymphocyte receptor signaling pathway" EXACT [] +synonym: "negative regulation of B-lymphocyte receptor signalling pathway" EXACT [] +is_a: GO:0050855 ! regulation of B cell receptor signaling pathway +is_a: GO:0050858 ! negative regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050853 ! B cell receptor signaling pathway +relationship: negatively_regulates GO:0050853 ! B cell receptor signaling pathway + +[Term] +id: GO:0050860 +name: negative regulation of T cell receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] +synonym: "down regulation of T cell receptor signaling pathway" EXACT [] +synonym: "down-regulation of T cell receptor signaling pathway" EXACT [] +synonym: "downregulation of T cell receptor signaling pathway" EXACT [] +synonym: "inhibition of T cell receptor signaling pathway" NARROW [] +synonym: "negative regulation of T cell receptor signalling pathway" EXACT [] +synonym: "negative regulation of T lymphocyte receptor signaling pathway" EXACT [] +synonym: "negative regulation of T lymphocyte receptor signalling pathway" EXACT [] +synonym: "negative regulation of T-cell receptor signaling pathway" EXACT [] +synonym: "negative regulation of T-lymphocyte receptor signaling pathway" EXACT [] +synonym: "negative regulation of T-lymphocyte receptor signalling pathway" EXACT [] +synonym: "negative regulation of TCR signaling pathway" EXACT [] +is_a: GO:0050856 ! regulation of T cell receptor signaling pathway +is_a: GO:0050858 ! negative regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050852 ! T cell receptor signaling pathway +relationship: negatively_regulates GO:0050852 ! T cell receptor signaling pathway + +[Term] +id: GO:0050861 +name: positive regulation of B cell receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] +synonym: "activation of B cell receptor signaling pathway" NARROW [] +synonym: "positive regulation of B cell receptor signalling pathway" EXACT [] +synonym: "positive regulation of B lymphocyte receptor signaling pathway" EXACT [] +synonym: "positive regulation of B lymphocyte receptor signalling pathway" EXACT [] +synonym: "positive regulation of B-cell receptor signaling pathway" EXACT [] +synonym: "positive regulation of B-cell receptor signalling pathway" EXACT [] +synonym: "positive regulation of B-lymphocyte receptor signaling pathway" EXACT [] +synonym: "positive regulation of B-lymphocyte receptor signalling pathway" EXACT [] +synonym: "stimulation of B cell receptor signaling pathway" NARROW [] +synonym: "up regulation of B cell receptor signaling pathway" EXACT [] +synonym: "up-regulation of B cell receptor signaling pathway" EXACT [] +synonym: "upregulation of B cell receptor signaling pathway" EXACT [] +is_a: GO:0050855 ! regulation of B cell receptor signaling pathway +is_a: GO:0050857 ! positive regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050853 ! B cell receptor signaling pathway +relationship: positively_regulates GO:0050853 ! B cell receptor signaling pathway + +[Term] +id: GO:0050862 +name: positive regulation of T cell receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] +synonym: "activation of T cell receptor signaling pathway" NARROW [] +synonym: "positive regulation of T cell receptor signalling pathway" EXACT [] +synonym: "positive regulation of T lymphocyte receptor signaling pathway" EXACT [] +synonym: "positive regulation of T lymphocyte receptor signalling pathway" EXACT [] +synonym: "positive regulation of T-cell receptor signaling pathway" EXACT [] +synonym: "positive regulation of T-lymphocyte receptor signaling pathway" EXACT [] +synonym: "positive regulation of T-lymphocyte receptor signalling pathway" EXACT [] +synonym: "positive regulation of TCR signaling pathway" EXACT [] +synonym: "stimulation of T cell receptor signaling pathway" NARROW [] +synonym: "up regulation of T cell receptor signaling pathway" EXACT [] +synonym: "up-regulation of T cell receptor signaling pathway" EXACT [] +synonym: "upregulation of T cell receptor signaling pathway" EXACT [] +is_a: GO:0050856 ! regulation of T cell receptor signaling pathway +is_a: GO:0050857 ! positive regulation of antigen receptor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050852 ! T cell receptor signaling pathway +relationship: positively_regulates GO:0050852 ! T cell receptor signaling pathway + +[Term] +id: GO:0050863 +name: regulation of T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] +synonym: "regulation of T lymphocyte activation" EXACT [] +synonym: "regulation of T-cell activation" EXACT [] +synonym: "regulation of T-lymphocyte activation" EXACT [] +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0042110 ! T cell activation +relationship: regulates GO:0042110 ! T cell activation + +[Term] +id: GO:0050864 +name: regulation of B cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of B cell activation." [GOC:ai] +synonym: "regulation of B lymphocyte activation" EXACT [] +synonym: "regulation of B-cell activation" EXACT [] +synonym: "regulation of B-lymphocyte activation" EXACT [] +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042113 ! B cell activation +relationship: regulates GO:0042113 ! B cell activation + +[Term] +id: GO:0050865 +name: regulation of cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001775 ! cell activation +relationship: regulates GO:0001775 ! cell activation + +[Term] +id: GO:0050866 +name: negative regulation of cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai] +synonym: "down regulation of cell activation" EXACT [] +synonym: "down-regulation of cell activation" EXACT [] +synonym: "downregulation of cell activation" EXACT [] +synonym: "inhibition of cell activation" NARROW [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001775 ! cell activation +relationship: negatively_regulates GO:0001775 ! cell activation + +[Term] +id: GO:0050867 +name: positive regulation of cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] +synonym: "activation of cell activation" NARROW [] +synonym: "stimulation of cell activation" NARROW [] +synonym: "up regulation of cell activation" EXACT [] +synonym: "up-regulation of cell activation" EXACT [] +synonym: "upregulation of cell activation" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001775 ! cell activation +relationship: positively_regulates GO:0001775 ! cell activation + +[Term] +id: GO:0050868 +name: negative regulation of T cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai] +synonym: "down regulation of T cell activation" EXACT [] +synonym: "down-regulation of T cell activation" EXACT [] +synonym: "downregulation of T cell activation" EXACT [] +synonym: "inhibition of T cell activation" NARROW [] +synonym: "negative regulation of T lymphocyte activation" EXACT [] +synonym: "negative regulation of T-cell activation" EXACT [] +synonym: "negative regulation of T-lymphocyte activation" EXACT [] +is_a: GO:0050863 ! regulation of T cell activation +is_a: GO:0051250 ! negative regulation of lymphocyte activation +is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042110 ! T cell activation +relationship: negatively_regulates GO:0042110 ! T cell activation + +[Term] +id: GO:0050869 +name: negative regulation of B cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation." [GOC:ai] +synonym: "down regulation of B cell activation" EXACT [] +synonym: "down-regulation of B cell activation" EXACT [] +synonym: "downregulation of B cell activation" EXACT [] +synonym: "inhibition of B cell activation" NARROW [] +synonym: "negative regulation of B lymphocyte activation" EXACT [] +synonym: "negative regulation of B-cell activation" EXACT [] +synonym: "negative regulation of B-lymphocyte activation" EXACT [] +is_a: GO:0050864 ! regulation of B cell activation +is_a: GO:0051250 ! negative regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042113 ! B cell activation +relationship: negatively_regulates GO:0042113 ! B cell activation + +[Term] +id: GO:0050870 +name: positive regulation of T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] +synonym: "activation of T cell activation" NARROW [] +synonym: "positive regulation of T lymphocyte activation" EXACT [] +synonym: "positive regulation of T-cell activation" EXACT [] +synonym: "positive regulation of T-lymphocyte activation" EXACT [] +synonym: "stimulation of T cell activation" NARROW [] +synonym: "up regulation of T cell activation" EXACT [] +synonym: "up-regulation of T cell activation" EXACT [] +synonym: "upregulation of T cell activation" EXACT [] +is_a: GO:0050863 ! regulation of T cell activation +is_a: GO:0051251 ! positive regulation of lymphocyte activation +is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042110 ! T cell activation +relationship: positively_regulates GO:0042110 ! T cell activation + +[Term] +id: GO:0050871 +name: positive regulation of B cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of B cell activation." [GOC:ai] +synonym: "activation of B cell activation" NARROW [] +synonym: "positive regulation of B lymphocyte activation" EXACT [] +synonym: "positive regulation of B-cell activation" EXACT [] +synonym: "positive regulation of B-lymphocyte activation" EXACT [] +synonym: "stimulation of B cell activation" NARROW [] +synonym: "up regulation of B cell activation" EXACT [] +synonym: "up-regulation of B cell activation" EXACT [] +synonym: "upregulation of B cell activation" EXACT [] +is_a: GO:0050864 ! regulation of B cell activation +is_a: GO:0051251 ! positive regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042113 ! B cell activation +relationship: positively_regulates GO:0042113 ! B cell activation + +[Term] +id: GO:0050872 +name: white fat cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole." [PMID:12508945] +synonym: "white adipocyte cell differentiation" EXACT [] +synonym: "white adipocyte differentiation" EXACT [] +is_a: GO:0045444 ! fat cell differentiation + +[Term] +id: GO:0050873 +name: brown fat cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria." [PMID:12588810] +synonym: "brown adipocyte cell differentiation" EXACT [] +synonym: "brown adipocyte differentiation" EXACT [] +is_a: GO:0045444 ! fat cell differentiation +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0050877 +name: nervous system process +namespace: biological_process +def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio] +subset: goslim_agr +subset: goslim_chembl +subset: goslim_flybase_ribbon +subset: goslim_generic +subset: goslim_pir +synonym: "neurological system process" EXACT [] +synonym: "neurophysiological process" EXACT [] +synonym: "pan-neural process" RELATED [] +is_a: GO:0003008 ! system process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13824 xsd:anyURI + +[Term] +id: GO:0050878 +name: regulation of body fluid levels +namespace: biological_process +def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_pir +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0050879 +name: multicellular organismal movement +namespace: biological_process +def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb] +subset: goslim_pir +is_a: GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0050881 +name: musculoskeletal movement +namespace: biological_process +def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph] +is_a: GO:0050879 ! multicellular organismal movement + +[Term] +id: GO:0050882 +name: voluntary musculoskeletal movement +namespace: biological_process +def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will." [GOC:dph] +is_a: GO:0050881 ! musculoskeletal movement + +[Term] +id: GO:0050883 +name: musculoskeletal movement, spinal reflex action +namespace: biological_process +def: "Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord." [GOC:dph] +is_a: GO:0050881 ! musculoskeletal movement +is_a: GO:0060004 ! reflex + +[Term] +id: GO:0050884 +name: neuromuscular process controlling posture +namespace: biological_process +def: "Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts." [GOC:dph, GOC:tb] +synonym: "regulation of posture" EXACT [] +is_a: GO:0050905 ! neuromuscular process + +[Term] +id: GO:0050885 +name: neuromuscular process controlling balance +namespace: biological_process +def: "Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors." [GOC:ai, GOC:dph] +synonym: "regulation of balance" RELATED [] +is_a: GO:0050905 ! neuromuscular process + +[Term] +id: GO:0050886 +name: endocrine process +namespace: biological_process +def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544] +subset: goslim_pir +synonym: "endocrine physiological process" EXACT [] +synonym: "endocrine physiology" EXACT [] +is_a: GO:0003008 ! system process + +[Term] +id: GO:0050887 +name: determination of sensory modality +namespace: biological_process +def: "The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain." [ISBN:0721619908] +is_a: GO:0050893 ! sensory processing + +[Term] +id: GO:0050888 +name: determination of stimulus location +namespace: biological_process +def: "The determination of where on the body surface, within the body or in the environment a stimulus originates." [ISBN:0721619908] +is_a: GO:0050893 ! sensory processing + +[Term] +id: GO:0050889 +name: determination of stimulus intensity +namespace: biological_process +def: "The determination of the perceived strength of a sensory stimulus." [ISBN:0721619908] +is_a: GO:0050893 ! sensory processing + +[Term] +id: GO:0050890 +name: cognition +namespace: biological_process +def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908] +subset: goslim_drosophila +xref: Wikipedia:Cognition +is_a: GO:0050877 ! nervous system process + +[Term] +id: GO:0050891 +name: multicellular organismal water homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism." [GOC:dph, GOC:tb] +synonym: "body fluid osmoregulation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0030104 ! water homeostasis +is_a: GO:0048871 ! multicellular organismal homeostasis +is_a: GO:0050878 ! regulation of body fluid levels + +[Term] +id: GO:0050892 +name: intestinal absorption +namespace: biological_process +def: "Any process in which nutrients are taken up from the contents of the intestine." [GOC:ai, GOC:dph] +is_a: GO:0006810 ! transport +is_a: GO:0022600 ! digestive system process + +[Term] +id: GO:0050893 +name: sensory processing +namespace: biological_process +def: "Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect." [GOC:dph, ISBN:0721662544] +is_a: GO:0050890 ! cognition +relationship: part_of GO:0007600 ! sensory perception + +[Term] +id: GO:0050894 +name: determination of affect +namespace: biological_process +def: "Any process in which an emotional response is associated with a particular sensory stimulation." [GOC:ai, GOC:dph, ISBN:0721662544] +is_a: GO:0050893 ! sensory processing + +[Term] +id: GO:0050896 +name: response to stimulus +namespace: biological_process +alt_id: GO:0051869 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_agr +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pir +synonym: "physiological response to stimulus" EXACT [] +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0050897 +name: cobalt ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cobalt (Co) ion." [GOC:ai] +synonym: "cobalt binding" EXACT [] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0050898 +name: nitrile metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile." [PMID:18987211] +synonym: "nitrile metabolism" EXACT [] +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0050899 +name: nitrile catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom." [ISBN:0721662544] +synonym: "nitrile breakdown" EXACT [] +synonym: "nitrile catabolism" EXACT [] +synonym: "nitrile degradation" EXACT [] +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0050898 ! nitrile metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0050900 +name: leukocyte migration +namespace: biological_process +def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +synonym: "immune cell migration" EXACT [] +synonym: "immune cell trafficking" EXACT [] +synonym: "leucocyte migration" EXACT [] +synonym: "leucocyte trafficking" EXACT [] +synonym: "leukocyte trafficking" EXACT [] +is_a: GO:0002376 ! immune system process +is_a: GO:0016477 ! cell migration + +[Term] +id: GO:0050901 +name: leukocyte tethering or rolling +namespace: biological_process +def: "Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)." [GOC:bf, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538, Wikipedia:Leukocyte_extravasation] +is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell +relationship: part_of GO:0045123 ! cellular extravasation + +[Term] +id: GO:0050902 +name: leukocyte adhesive activation +namespace: biological_process +def: "The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation." [ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +synonym: "leukocyte adhesive triggering" EXACT [] +is_a: GO:0045321 ! leukocyte activation +relationship: part_of GO:0045123 ! cellular extravasation + +[Term] +id: GO:0050903 +name: leukocyte activation-dependent arrest +namespace: biological_process +def: "The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation." [ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell +relationship: part_of GO:0045123 ! cellular extravasation + +[Term] +id: GO:0050904 +name: diapedesis +namespace: biological_process +def: "The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation." [ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] +comment: Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic. +is_a: GO:0050900 ! leukocyte migration +relationship: part_of GO:0045123 ! cellular extravasation + +[Term] +id: GO:0050905 +name: neuromuscular process +namespace: biological_process +def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai] +synonym: "neuromotor process" EXACT [] +synonym: "neuromuscular physiological process" EXACT [] +is_a: GO:0050877 ! nervous system process + +[Term] +id: GO:0050906 +name: detection of stimulus involved in sensory perception +namespace: biological_process +def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph] +synonym: "sensory detection of stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of stimulus" EXACT [] +synonym: "sensory perception, stimulus detection" EXACT [] +synonym: "sensory transduction" EXACT [] +xref: Wikipedia:Transduction_(physiology) +is_a: GO:0051606 ! detection of stimulus +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0007600 ! sensory perception + +[Term] +id: GO:0050907 +name: detection of chemical stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] +synonym: "sensory detection of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during sensory perception" EXACT [] +synonym: "sensory perception, sensory detection of chemical stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0007606 ! sensory perception of chemical stimulus + +[Term] +id: GO:0050908 +name: detection of light stimulus involved in visual perception +namespace: biological_process +def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +synonym: "sensory detection of light during visual perception" EXACT [] +synonym: "sensory detection of light stimulus during visual perception" EXACT [] +synonym: "sensory transduction of light during visual perception" EXACT [] +synonym: "sensory transduction of light stimulus during visual perception" EXACT [] +synonym: "visual perception, detection of light stimulus" EXACT [] +synonym: "visual perception, sensory transduction during perception of light" EXACT [] +synonym: "visual perception, sensory transduction of light stimulus" EXACT [] +is_a: GO:0009584 ! detection of visible light +is_a: GO:0050962 ! detection of light stimulus involved in sensory perception +intersection_of: GO:0009583 ! detection of light stimulus +intersection_of: part_of GO:0007601 ! visual perception +relationship: part_of GO:0007601 ! visual perception + +[Term] +id: GO:0050909 +name: sensory perception of taste +namespace: biological_process +def: "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." [GOC:ai] +synonym: "gustation" EXACT [] +synonym: "sense of taste" EXACT [] +synonym: "taste" EXACT [] +synonym: "taste perception" EXACT [] +xref: Wikipedia:Taste +is_a: GO:0007606 ! sensory perception of chemical stimulus + +[Term] +id: GO:0050910 +name: detection of mechanical stimulus involved in sensory perception of sound +namespace: biological_process +alt_id: GO:0009592 +alt_id: GO:0055128 +def: "The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal." [GOC:ai] +synonym: "detection of sound" EXACT [] +synonym: "hearing, sensory transduction of sound" EXACT [] +synonym: "perception of sound, detection of mechanical stimulus" EXACT [] +synonym: "perception of sound, sensory detection of mechanical stimulus" EXACT [] +synonym: "perception of sound, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during perception of sound" EXACT [] +synonym: "sensory transduction of mechanical stimulus during perception of sound" EXACT [] +synonym: "sensory transduction of sound" EXACT [] +is_a: GO:0050877 ! nervous system process +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0007605 ! sensory perception of sound +relationship: part_of GO:0007605 ! sensory perception of sound + +[Term] +id: GO:0050911 +name: detection of chemical stimulus involved in sensory perception of smell +namespace: biological_process +def: "The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal." [GOC:ai] +synonym: "perception of smell, detection of chemical stimulus" EXACT [] +synonym: "perception of smell, sensory detection of chemical stimulus" EXACT [] +synonym: "perception of smell, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of smell" EXACT [] +synonym: "sensory detection of scent" EXACT [] +synonym: "sensory detection of smell" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of smell" EXACT [] +synonym: "sensory transduction of scent" EXACT [] +synonym: "sensory transduction of smell" EXACT [] +is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0007608 ! sensory perception of smell +relationship: part_of GO:0007608 ! sensory perception of smell + +[Term] +id: GO:0050912 +name: detection of chemical stimulus involved in sensory perception of taste +namespace: biological_process +def: "The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal." [GOC:ai] +synonym: "perception of taste, detection of chemical stimulus" EXACT [] +synonym: "perception of taste, sensory detection of chemical stimulus" EXACT [] +synonym: "perception of taste, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of taste" EXACT [] +synonym: "sensory detection of taste" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of taste" EXACT [] +synonym: "sensory transduction of taste" EXACT [] +synonym: "taste perception" BROAD [] +is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050909 ! sensory perception of taste +relationship: part_of GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050913 +name: sensory perception of bitter taste +namespace: biological_process +def: "The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "bitter taste perception" EXACT [] +is_a: GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050914 +name: sensory perception of salty taste +namespace: biological_process +def: "The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "salty taste perception" EXACT [] +is_a: GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050915 +name: sensory perception of sour taste +namespace: biological_process +def: "The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "sour taste perception" EXACT [] +is_a: GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050916 +name: sensory perception of sweet taste +namespace: biological_process +def: "The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "sweet taste perception" EXACT [] +is_a: GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050917 +name: sensory perception of umami taste +namespace: biological_process +def: "The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process." [GOC:ai] +synonym: "umami taste perception" EXACT [] +is_a: GO:0050909 ! sensory perception of taste + +[Term] +id: GO:0050918 +name: positive chemotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a higher concentration of a chemical." [GOC:ai, GOC:bf, GOC:isa_complete] +synonym: "chemoattraction" EXACT [] +is_a: GO:0006935 ! chemotaxis + +[Term] +id: GO:0050919 +name: negative chemotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a lower concentration of a chemical." [GOC:ai, GOC:bf, GOC:isa_complete] +synonym: "chemoaversion" EXACT [] +synonym: "chemorepulsion" EXACT [] +is_a: GO:0006935 ! chemotaxis + +[Term] +id: GO:0050920 +name: regulation of chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." [GOC:ai] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0040012 ! regulation of locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006935 ! chemotaxis +relationship: regulates GO:0006935 ! chemotaxis + +[Term] +id: GO:0050921 +name: positive regulation of chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." [GOC:ai] +synonym: "activation of chemotaxis" NARROW [] +synonym: "stimulation of chemotaxis" NARROW [] +synonym: "up regulation of chemotaxis" EXACT [] +synonym: "up-regulation of chemotaxis" EXACT [] +synonym: "upregulation of chemotaxis" EXACT [] +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0040017 ! positive regulation of locomotion +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006935 ! chemotaxis +relationship: positively_regulates GO:0006935 ! chemotaxis + +[Term] +id: GO:0050922 +name: negative regulation of chemotaxis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." [GOC:ai] +synonym: "down regulation of chemotaxis" EXACT [] +synonym: "down-regulation of chemotaxis" EXACT [] +synonym: "downregulation of chemotaxis" EXACT [] +synonym: "inhibition of chemotaxis" NARROW [] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0040013 ! negative regulation of locomotion +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006935 ! chemotaxis +relationship: negatively_regulates GO:0006935 ! chemotaxis + +[Term] +id: GO:0050923 +name: regulation of negative chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." [GOC:ai] +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050919 ! negative chemotaxis +relationship: regulates GO:0050919 ! negative chemotaxis + +[Term] +id: GO:0050924 +name: positive regulation of negative chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." [GOC:ai] +synonym: "activation of negative chemotaxis" NARROW [] +synonym: "stimulation of negative chemotaxis" NARROW [] +synonym: "up regulation of negative chemotaxis" EXACT [] +synonym: "up-regulation of negative chemotaxis" EXACT [] +synonym: "upregulation of negative chemotaxis" EXACT [] +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:0050923 ! regulation of negative chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050919 ! negative chemotaxis +relationship: positively_regulates GO:0050919 ! negative chemotaxis + +[Term] +id: GO:0050925 +name: negative regulation of negative chemotaxis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." [GOC:ai] +synonym: "down regulation of negative chemotaxis" EXACT [] +synonym: "down-regulation of negative chemotaxis" EXACT [] +synonym: "downregulation of negative chemotaxis" EXACT [] +synonym: "inhibition of negative chemotaxis" NARROW [] +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0050923 ! regulation of negative chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050919 ! negative chemotaxis +relationship: negatively_regulates GO:0050919 ! negative chemotaxis + +[Term] +id: GO:0050926 +name: regulation of positive chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." [GOC:ai] +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050918 ! positive chemotaxis +relationship: regulates GO:0050918 ! positive chemotaxis + +[Term] +id: GO:0050927 +name: positive regulation of positive chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." [GOC:ai] +synonym: "activation of positive chemotaxis" NARROW [] +synonym: "stimulation of positive chemotaxis" NARROW [] +synonym: "up regulation of positive chemotaxis" EXACT [] +synonym: "up-regulation of positive chemotaxis" EXACT [] +synonym: "upregulation of positive chemotaxis" EXACT [] +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:0050926 ! regulation of positive chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050918 ! positive chemotaxis +relationship: positively_regulates GO:0050918 ! positive chemotaxis + +[Term] +id: GO:0050928 +name: negative regulation of positive chemotaxis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." [GOC:ai] +synonym: "down regulation of positive chemotaxis" EXACT [] +synonym: "down-regulation of positive chemotaxis" EXACT [] +synonym: "downregulation of positive chemotaxis" EXACT [] +synonym: "inhibition of positive chemotaxis" NARROW [] +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0050926 ! regulation of positive chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050918 ! positive chemotaxis +relationship: negatively_regulates GO:0050918 ! positive chemotaxis + +[Term] +id: GO:0050929 +name: induction of negative chemotaxis +namespace: biological_process +def: "Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." [GOC:ai] +is_a: GO:0050924 ! positive regulation of negative chemotaxis + +[Term] +id: GO:0050930 +name: induction of positive chemotaxis +namespace: biological_process +def: "Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." [GOC:ai] +is_a: GO:0050927 ! positive regulation of positive chemotaxis + +[Term] +id: GO:0050931 +name: pigment cell differentiation +namespace: biological_process +alt_id: GO:0043357 +alt_id: GO:0043358 +def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh] +comment: Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore. +synonym: "chromatophore differentiation" EXACT [] +synonym: "pigmented cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0048066 ! developmental pigmentation + +[Term] +id: GO:0050932 +name: regulation of pigment cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0048070 ! regulation of developmental pigmentation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050931 ! pigment cell differentiation +relationship: regulates GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0050933 +name: early stripe melanocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development)." [PMID:11858836] +synonym: "early stripe melanocyte cell differentiation" EXACT [] +synonym: "early stripe melanophore differentiation" EXACT [] +is_a: GO:0030318 ! melanocyte differentiation + +[Term] +id: GO:0050934 +name: late stripe melanocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development)." [PMID:11858836] +synonym: "late stripe melanocyte cell differentiation" EXACT [] +synonym: "late stripe melanophore differentiation" EXACT [] +is_a: GO:0030318 ! melanocyte differentiation + +[Term] +id: GO:0050935 +name: iridophore differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance." [GOC:jid, GOC:mh, PMID:11858836] +synonym: "iridophore cell differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0050936 +name: xanthophore differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance." [GOC:jid, GOC:mh, PMID:11858836] +comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. +synonym: "xanthophore cell differentiation" EXACT [] +is_a: GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0050937 +name: regulation of iridophore differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of iridophore differentiation." [GOC:ai] +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050935 ! iridophore differentiation +relationship: regulates GO:0050935 ! iridophore differentiation + +[Term] +id: GO:0050938 +name: regulation of xanthophore differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xanthophore differentiation." [GOC:ai] +comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050936 ! xanthophore differentiation +relationship: regulates GO:0050936 ! xanthophore differentiation + +[Term] +id: GO:0050939 +name: regulation of early stripe melanocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] +synonym: "regulation of early stripe melanophore differentiation" EXACT [] +is_a: GO:0045634 ! regulation of melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050933 ! early stripe melanocyte differentiation +relationship: regulates GO:0050933 ! early stripe melanocyte differentiation + +[Term] +id: GO:0050940 +name: regulation of late stripe melanocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] +synonym: "regulation of late stripe melanophore differentiation" EXACT [] +is_a: GO:0045634 ! regulation of melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050934 ! late stripe melanocyte differentiation +relationship: regulates GO:0050934 ! late stripe melanocyte differentiation + +[Term] +id: GO:0050941 +name: negative regulation of pigment cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] +synonym: "down regulation of pigment cell differentiation" EXACT [] +synonym: "down-regulation of pigment cell differentiation" EXACT [] +synonym: "downregulation of pigment cell differentiation" EXACT [] +synonym: "inhibition of pigment cell differentiation" NARROW [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0048086 ! negative regulation of developmental pigmentation +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050931 ! pigment cell differentiation +relationship: negatively_regulates GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0050942 +name: positive regulation of pigment cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] +synonym: "activation of pigment cell differentiation" NARROW [] +synonym: "stimulation of pigment cell differentiation" NARROW [] +synonym: "up regulation of pigment cell differentiation" EXACT [] +synonym: "up-regulation of pigment cell differentiation" EXACT [] +synonym: "upregulation of pigment cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0048087 ! positive regulation of developmental pigmentation +is_a: GO:0050932 ! regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050931 ! pigment cell differentiation +relationship: positively_regulates GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0050943 +name: negative regulation of iridophore differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation." [GOC:ai] +synonym: "down regulation of iridophore differentiation" EXACT [] +synonym: "down-regulation of iridophore differentiation" EXACT [] +synonym: "downregulation of iridophore differentiation" EXACT [] +synonym: "inhibition of iridophore differentiation" NARROW [] +is_a: GO:0050937 ! regulation of iridophore differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050935 ! iridophore differentiation +relationship: negatively_regulates GO:0050935 ! iridophore differentiation + +[Term] +id: GO:0050944 +name: negative regulation of xanthophore differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation." [GOC:ai] +comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. +synonym: "down regulation of xanthophore differentiation" EXACT [] +synonym: "down-regulation of xanthophore differentiation" EXACT [] +synonym: "downregulation of xanthophore differentiation" EXACT [] +synonym: "inhibition of xanthophore differentiation" NARROW [] +is_a: GO:0050938 ! regulation of xanthophore differentiation +is_a: GO:0050941 ! negative regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050936 ! xanthophore differentiation +relationship: negatively_regulates GO:0050936 ! xanthophore differentiation + +[Term] +id: GO:0050945 +name: positive regulation of iridophore differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of iridophore differentiation." [GOC:ai] +synonym: "activation of iridophore differentiation" NARROW [] +synonym: "stimulation of iridophore differentiation" NARROW [] +synonym: "up regulation of iridophore differentiation" EXACT [] +synonym: "up-regulation of iridophore differentiation" EXACT [] +synonym: "upregulation of iridophore differentiation" EXACT [] +is_a: GO:0050937 ! regulation of iridophore differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050935 ! iridophore differentiation +relationship: positively_regulates GO:0050935 ! iridophore differentiation + +[Term] +id: GO:0050946 +name: positive regulation of xanthophore differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xanthophore differentiation." [GOC:ai] +comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. +synonym: "activation of xanthophore differentiation" NARROW [] +synonym: "stimulation of xanthophore differentiation" NARROW [] +synonym: "up regulation of xanthophore differentiation" EXACT [] +synonym: "up-regulation of xanthophore differentiation" EXACT [] +synonym: "upregulation of xanthophore differentiation" EXACT [] +is_a: GO:0050938 ! regulation of xanthophore differentiation +is_a: GO:0050942 ! positive regulation of pigment cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050936 ! xanthophore differentiation +relationship: positively_regulates GO:0050936 ! xanthophore differentiation + +[Term] +id: GO:0050947 +name: negative regulation of early stripe melanocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] +synonym: "down regulation of early stripe melanocyte differentiation" EXACT [] +synonym: "down-regulation of early stripe melanocyte differentiation" EXACT [] +synonym: "downregulation of early stripe melanocyte differentiation" EXACT [] +synonym: "inhibition of early stripe melanocyte differentiation" NARROW [] +synonym: "negative regulation of early stripe melanophore differentiation" EXACT [] +is_a: GO:0045635 ! negative regulation of melanocyte differentiation +is_a: GO:0050939 ! regulation of early stripe melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050933 ! early stripe melanocyte differentiation +relationship: negatively_regulates GO:0050933 ! early stripe melanocyte differentiation + +[Term] +id: GO:0050948 +name: positive regulation of early stripe melanocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] +synonym: "activation of early stripe melanocyte differentiation" NARROW [] +synonym: "positive regulation of early stripe melanophore differentiation" EXACT [] +synonym: "stimulation of early stripe melanocyte differentiation" NARROW [] +synonym: "up regulation of early stripe melanocyte differentiation" EXACT [] +synonym: "up-regulation of early stripe melanocyte differentiation" EXACT [] +synonym: "upregulation of early stripe melanocyte differentiation" EXACT [] +is_a: GO:0045636 ! positive regulation of melanocyte differentiation +is_a: GO:0050939 ! regulation of early stripe melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050933 ! early stripe melanocyte differentiation +relationship: positively_regulates GO:0050933 ! early stripe melanocyte differentiation + +[Term] +id: GO:0050949 +name: negative regulation of late stripe melanocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] +synonym: "down regulation of late stripe melanocyte differentiation" EXACT [] +synonym: "down-regulation of late stripe melanocyte differentiation" EXACT [] +synonym: "downregulation of late stripe melanocyte differentiation" EXACT [] +synonym: "inhibition of late stripe melanocyte differentiation" NARROW [] +synonym: "negative regulation of late stripe melanophore differentiation" EXACT [] +is_a: GO:0045635 ! negative regulation of melanocyte differentiation +is_a: GO:0050940 ! regulation of late stripe melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050934 ! late stripe melanocyte differentiation +relationship: negatively_regulates GO:0050934 ! late stripe melanocyte differentiation + +[Term] +id: GO:0050950 +name: positive regulation of late stripe melanocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] +synonym: "activation of late stripe melanocyte differentiation" NARROW [] +synonym: "positive regulation of late stripe melanophore differentiation" EXACT [] +synonym: "stimulation of late stripe melanocyte differentiation" NARROW [] +synonym: "up regulation of late stripe melanocyte differentiation" EXACT [] +synonym: "up-regulation of late stripe melanocyte differentiation" EXACT [] +synonym: "upregulation of late stripe melanocyte differentiation" EXACT [] +is_a: GO:0045636 ! positive regulation of melanocyte differentiation +is_a: GO:0050940 ! regulation of late stripe melanocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050934 ! late stripe melanocyte differentiation +relationship: positively_regulates GO:0050934 ! late stripe melanocyte differentiation + +[Term] +id: GO:0050951 +name: sensory perception of temperature stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "sensory perception of thermal stimulus" EXACT [] +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0050952 +name: sensory perception of electrical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0050953 +name: sensory perception of light stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0050954 +name: sensory perception of mechanical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] +synonym: "chemi-mechanical coupling" RELATED [] +synonym: "mechanosensory perception" EXACT [] +synonym: "perception of mechanical stimulus" EXACT [] +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0050955 +name: thermoception +namespace: biological_process +def: "The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature)." [GOC:ai, Wikipedia:Thermoception] +synonym: "thermoreception" EXACT [] +xref: Wikipedia:Thermoception +is_a: GO:0050951 ! sensory perception of temperature stimulus + +[Term] +id: GO:0050956 +name: electroception +namespace: biological_process +def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception] +synonym: "electroception sense" EXACT [] +synonym: "electroceptive sense" EXACT [] +xref: Wikipedia:Electroreception +is_a: GO:0050952 ! sensory perception of electrical stimulus + +[Term] +id: GO:0050957 +name: equilibrioception +namespace: biological_process +def: "The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion." [http://www.medterms.com] +synonym: "sensory perception of orientation with respect to gravity" EXACT [] +xref: Wikipedia:Equilibrioception +is_a: GO:0007600 ! sensory perception +relationship: part_of GO:0050885 ! neuromuscular process controlling balance + +[Term] +id: GO:0050958 +name: magnetoreception +namespace: biological_process +def: "The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light." [GOC:ai, PMID:15886990, Wikipedia:Magnetoception] +synonym: "magnetoception" EXACT [] +synonym: "sensory perception of magnetic field" EXACT [] +xref: Wikipedia:Magnetoception +is_a: GO:0007600 ! sensory perception + +[Term] +id: GO:0050959 +name: echolocation +namespace: biological_process +def: "Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning." [PMID:16005275, Wikipedia:Animal_echolocation] +synonym: "perception of environment using reflected sound waves" EXACT [] +xref: Wikipedia:Echolocation +is_a: GO:0050877 ! nervous system process + +[Term] +id: GO:0050960 +name: detection of temperature stimulus involved in thermoception +namespace: biological_process +def: "The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception." [GOC:ai, GOC:dos] +synonym: "sensory detection of temperature stimulus during thermoception" EXACT [] +synonym: "sensory detection of thermal stimulus during thermoception" EXACT [] +synonym: "sensory transduction of temperature stimulus during thermoception" EXACT [] +synonym: "sensory transduction of thermal stimulus during thermoception" EXACT [] +synonym: "thermoception, sensory detection of temperature stimulus" EXACT [] +synonym: "thermoception, sensory detection of thermal stimulus" EXACT [] +synonym: "thermoception, sensory transduction of temperature stimulus" EXACT [] +synonym: "thermoception, sensory transduction of thermal stimulus" EXACT [] +is_a: GO:0050961 ! detection of temperature stimulus involved in sensory perception +intersection_of: GO:0016048 ! detection of temperature stimulus +intersection_of: part_of GO:0050955 ! thermoception +relationship: part_of GO:0050955 ! thermoception + +[Term] +id: GO:0050961 +name: detection of temperature stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] +synonym: "sensory detection of heat stimulus during sensory perception" NARROW [] +synonym: "sensory detection of temperature stimulus" EXACT [] +synonym: "sensory detection of temperature stimulus during sensory perception" EXACT [] +synonym: "sensory detection of thermal stimulus during sensory perception" EXACT [] +synonym: "sensory perception, sensory detection of heat stimulus" NARROW [] +synonym: "sensory perception, sensory detection of temperature stimulus" EXACT [] +synonym: "sensory perception, sensory detection of thermal stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of heat stimulus" NARROW [] +synonym: "sensory perception, sensory transduction of temperature stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of thermal stimulus" EXACT [] +synonym: "sensory transduction of heat stimulus during sensory perception" NARROW [] +synonym: "sensory transduction of temperature stimulus" EXACT [] +synonym: "sensory transduction of temperature stimulus during sensory perception" EXACT [] +synonym: "sensory transduction of thermal stimulus during sensory perception" EXACT [] +is_a: GO:0016048 ! detection of temperature stimulus +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +intersection_of: GO:0016048 ! detection of temperature stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0050951 ! sensory perception of temperature stimulus + +[Term] +id: GO:0050962 +name: detection of light stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos] +synonym: "sensory detection of light stimulus" EXACT [] +synonym: "sensory detection of light stimulus during sensory perception" EXACT [] +synonym: "sensory perception, sensory detection of light stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of light stimulus" EXACT [] +synonym: "sensory transduction of light stimulus" EXACT [] +synonym: "sensory transduction of light stimulus during sensory perception" EXACT [] +is_a: GO:0009583 ! detection of light stimulus +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +intersection_of: GO:0009583 ! detection of light stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0050953 ! sensory perception of light stimulus + +[Term] +id: GO:0050963 +name: detection of electrical stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] +synonym: "sensory detection of electrical stimulus" EXACT [] +synonym: "sensory detection of electrical stimulus during sensory perception" EXACT [] +synonym: "sensory perception, sensory detection of electrical stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT [] +synonym: "sensory transduction of electrical stimulus" EXACT [] +synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT [] +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +is_a: GO:0050981 ! detection of electrical stimulus +intersection_of: GO:0050981 ! detection of electrical stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0050952 ! sensory perception of electrical stimulus + +[Term] +id: GO:0050964 +name: detection of electrical stimulus involved in electroception +namespace: biological_process +def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +synonym: "detection of electrical stimulus during electroreception" RELATED [GOC:dph, GOC:tb] +synonym: "electroception, detection of electrical stimulus" EXACT [] +synonym: "electroception, sensory detection of electrical stimulus" EXACT [] +synonym: "electroception, sensory transduction" EXACT [] +synonym: "electroception, sensory transduction of electrical stimulus" EXACT [] +synonym: "sensory detection of electrical stimulus during electroception" RELATED [] +synonym: "sensory transduction of electrical stimulus during electroception" RELATED [] +is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception +intersection_of: GO:0050981 ! detection of electrical stimulus +intersection_of: part_of GO:0050956 ! electroception +relationship: part_of GO:0050956 ! electroception + +[Term] +id: GO:0050965 +name: detection of temperature stimulus involved in sensory perception of pain +namespace: biological_process +def: "The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +synonym: "perception of pain, detection of temperature stimulus" EXACT [] +synonym: "perception of pain, sensory detection of temperature stimulus" EXACT [] +synonym: "perception of pain, sensory transduction of temperature stimulus" EXACT [] +synonym: "sensory detection of temperature stimulus during perception of pain" EXACT [] +synonym: "sensory detection of thermal stimulus during sensory perception of pain" EXACT [] +synonym: "sensory perception of pain, sensory detection of thermal stimulus" EXACT [] +synonym: "sensory perception of pain, sensory transduction of thermal stimulus" EXACT [] +synonym: "sensory transduction of temperature stimulus during perception of pain" EXACT [] +synonym: "sensory transduction of thermal stimulus during sensory perception of pain" EXACT [] +synonym: "thermal nociception" RELATED [GOC:pr] +is_a: GO:0050961 ! detection of temperature stimulus involved in sensory perception +is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain +intersection_of: GO:0016048 ! detection of temperature stimulus +intersection_of: part_of GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0050966 +name: detection of mechanical stimulus involved in sensory perception of pain +namespace: biological_process +def: "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +synonym: "mechanical nociception" RELATED [GOC:pr] +synonym: "perception of pain, detection of mechanical stimulus" EXACT [] +synonym: "perception of pain, sensory detection of mechanical stimulus" EXACT [] +synonym: "perception of pain, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during perception of pain" EXACT [] +synonym: "sensory transduction of mechanical stimulus during perception of pain" EXACT [] +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0050967 +name: detection of electrical stimulus involved in sensory perception of pain +namespace: biological_process +def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] +synonym: "detection of electrical stimulus during sensory perception of pain" RELATED [GOC:dph, GOC:tb] +synonym: "perception of pain, detection of electrical stimulus" EXACT [] +synonym: "perception of pain, sensory detection of electrical stimulus" EXACT [] +synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT [] +synonym: "sensory detection of electrical stimulus during perception of pain" RELATED [] +synonym: "sensory transduction of electrical stimulus during perception of pain" RELATED [] +is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception +is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain +intersection_of: GO:0050981 ! detection of electrical stimulus +intersection_of: part_of GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0050968 +name: detection of chemical stimulus involved in sensory perception of pain +namespace: biological_process +def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai] +synonym: "chemical nociception" RELATED [GOC:pr] +synonym: "perception of pain, detection of chemical stimulus" EXACT [] +synonym: "perception of pain, sensory detection of chemical stimulus" EXACT [] +synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during perception of pain" EXACT [] +synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT [] +is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception +is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0050969 +name: detection of chemical stimulus involved in magnetoreception +namespace: biological_process +def: "The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states." [GOC:ai, GOC:dos] +synonym: "magnetoception, sensory transduction of chemical stimulus" EXACT [] +synonym: "magnetoreception, detection of chemical stimulus" EXACT [] +synonym: "magnetoreception, sensory detection of chemical stimulus" EXACT [] +synonym: "magnetoreception, sensory transduction of chemical stimulus" EXACT [] +synonym: "sensory detection of chemical stimulus during magnetoreception" EXACT [] +synonym: "sensory transduction of chemical stimulus during magnetoreception" EXACT [] +is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception +intersection_of: GO:0009593 ! detection of chemical stimulus +intersection_of: part_of GO:0050958 ! magnetoreception +relationship: part_of GO:0050977 ! magnetoreception by sensory perception of chemical stimulus + +[Term] +id: GO:0050970 +name: detection of electrical stimulus involved in magnetoreception +namespace: biological_process +def: "The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field." [GOC:ai, GOC:dos, GOC:dph, GOC:tb, PMID:15886990, Wikipedia:Magnetoception] +synonym: "detection of electrical stimulus during magnetoreception" RELATED [GOC:dph, GOC:tb] +synonym: "magnetoception, sensory transduction of electrical stimulus" EXACT [] +synonym: "magnetoreception, detection of electrical stimulus" EXACT [] +synonym: "magnetoreception, sensory detection of electrical stimulus" EXACT [] +synonym: "magnetoreception, sensory transduction of electrical stimulus" EXACT [] +synonym: "sensory detection of electrical stimulus during magnetoreception" RELATED [] +synonym: "sensory transduction of electrical stimulus during magnetoreception" RELATED [] +is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception +intersection_of: GO:0050981 ! detection of electrical stimulus +intersection_of: part_of GO:0050958 ! magnetoreception +relationship: part_of GO:0050978 ! magnetoreception by sensory perception of electrical stimulus + +[Term] +id: GO:0050971 +name: detection of mechanical stimulus involved in magnetoreception +namespace: biological_process +def: "The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field." [GOC:ai, GOC:dos] +synonym: "magnetoception, sensory transduction of mechanical stimulus" EXACT [] +synonym: "magnetoreception, detection of mechanical stimulus" EXACT [] +synonym: "magnetoreception, sensory detection of mechanical stimulus" EXACT [] +synonym: "magnetoreception, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during magnetoreception" EXACT [] +synonym: "sensory transduction of mechanical stimulus during magnetoreception" EXACT [] +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0050958 ! magnetoreception +relationship: part_of GO:0050979 ! magnetoreception by sensory perception of mechanical stimulus + +[Term] +id: GO:0050972 +name: detection of mechanical stimulus involved in echolocation +namespace: biological_process +def: "The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave." [GOC:ai, GOC:dos] +synonym: "echolocation, detection of mechanical stimulus" EXACT [] +synonym: "echolocation, sensory detection of mechanical stimulus" EXACT [] +synonym: "echolocation, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during echolocation" EXACT [] +synonym: "sensory transduction of mechanical stimulus during echolocation" EXACT [] +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0050959 ! echolocation +relationship: part_of GO:0050959 ! echolocation + +[Term] +id: GO:0050973 +name: detection of mechanical stimulus involved in equilibrioception +namespace: biological_process +def: "The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears." [GOC:ai, GOC:dos] +synonym: "equilibrioception, detection of mechanical stimulus" EXACT [] +synonym: "equilibrioception, sensory detection of mechanical stimulus" EXACT [] +synonym: "equilibrioception, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during equilibrioception" EXACT [] +synonym: "sensory transduction of mechanical stimulus during equilibrioception" EXACT [] +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0050957 ! equilibrioception +relationship: part_of GO:0050957 ! equilibrioception + +[Term] +id: GO:0050974 +name: detection of mechanical stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] +synonym: "sensory detection of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during sensory perception" EXACT [] +synonym: "sensory perception, sensory detection of mechanical stimulus" EXACT [] +synonym: "sensory perception, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory transduction of mechanical stimulus during sensory perception" EXACT [] +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +is_a: GO:0050982 ! detection of mechanical stimulus +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0007600 ! sensory perception +relationship: part_of GO:0050954 ! sensory perception of mechanical stimulus + +[Term] +id: GO:0050975 +name: sensory perception of touch +namespace: biological_process +def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai] +synonym: "perception of touch" EXACT [] +synonym: "tactile sense" EXACT [] +synonym: "taction" EXACT [] +synonym: "tactition" EXACT [] +xref: Wikipedia:Touch +is_a: GO:0050954 ! sensory perception of mechanical stimulus + +[Term] +id: GO:0050976 +name: detection of mechanical stimulus involved in sensory perception of touch +namespace: biological_process +def: "The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +synonym: "perception of touch, detection of mechanical stimulus" EXACT [] +synonym: "perception of touch, sensory detection of mechanical stimulus" EXACT [] +synonym: "perception of touch, sensory transduction of mechanical stimulus" EXACT [] +synonym: "sensory detection of mechanical stimulus during perception of touch" EXACT [] +synonym: "sensory transduction of mechanical stimulus during perception of touch" EXACT [] +synonym: "tactition, sensory detection of mechanical stimulus" EXACT [] +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0050975 ! sensory perception of touch +relationship: part_of GO:0050975 ! sensory perception of touch + +[Term] +id: GO:0050977 +name: magnetoreception by sensory perception of chemical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli." [GOC:ai, PMID:15886990, Wikipedia:Magnetoception] +synonym: "magnetoreception by chemical stimulus" EXACT [] +synonym: "magnetoreception through chemical stimulus" EXACT [] +synonym: "magnetoreception, sensory perception of chemical stimulus" EXACT [] +synonym: "magnetoreception, using chemical stimulus" EXACT [GOC:dph, GOC:tb] +is_a: GO:0007606 ! sensory perception of chemical stimulus +is_a: GO:0050958 ! magnetoreception + +[Term] +id: GO:0050978 +name: magnetoreception by sensory perception of electrical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish." [GOC:ai, PMID:15886990, Wikipedia:Magnetoception] +synonym: "magnetoreception by electrical stimulus" EXACT [] +synonym: "magnetoreception through electrical stimulus" EXACT [] +synonym: "magnetoreception, sensory perception of electrical stimulus" EXACT [] +synonym: "magnetoreception, using electrical stimulus" EXACT [GOC:dph, GOC:tb] +is_a: GO:0050952 ! sensory perception of electrical stimulus +is_a: GO:0050958 ! magnetoreception + +[Term] +id: GO:0050979 +name: magnetoreception by sensory perception of mechanical stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field." [GOC:ai, PMID:15886990, Wikipedia:Magnetoception] +synonym: "magnetoreception through mechanical stimulus" EXACT [] +synonym: "magnetoreception, sensory perception of mechanical stimulus" EXACT [] +synonym: "magnetoreception, using mechanical stimulus" EXACT [GOC:dph, GOC:tb] +is_a: GO:0050954 ! sensory perception of mechanical stimulus +is_a: GO:0050958 ! magnetoreception + +[Term] +id: GO:0050980 +name: detection of light stimulus involved in magnetoreception +namespace: biological_process +def: "The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field." [GOC:ai, GOC:dos, PMID:15886990, Wikipedia:Magnetoception] +synonym: "magnetoreception, detection of light stimulus" EXACT [] +synonym: "magnetoreception, sensory detection of light stimulus" EXACT [] +synonym: "magnetoreception, sensory transduction of light stimulus" EXACT [] +synonym: "sensory detection of light stimulus during magnetoreception" EXACT [] +synonym: "sensory transduction of light stimulus during magnetoreception" EXACT [] +is_a: GO:0050962 ! detection of light stimulus involved in sensory perception +intersection_of: GO:0009583 ! detection of light stimulus +intersection_of: part_of GO:0050958 ! magnetoreception +relationship: part_of GO:0050958 ! magnetoreception + +[Term] +id: GO:0050981 +name: detection of electrical stimulus +namespace: biological_process +def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +is_a: GO:0009582 ! detection of abiotic stimulus +is_a: GO:0051602 ! response to electrical stimulus + +[Term] +id: GO:0050982 +name: detection of mechanical stimulus +namespace: biological_process +def: "The series of events by which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009582 ! detection of abiotic stimulus +is_a: GO:0009612 ! response to mechanical stimulus + +[Term] +id: GO:0050983 +name: obsolete deoxyhypusine biosynthetic process from spermidine +namespace: biological_process +def: "OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+." [MetaCyc:1.1.1.249-RXN] +comment: The reason for obsoletion is that although GO:0050983 is described as a multistep process, the entire reaction is carried out by a single enzyme, therefore we would define it as the molecular function GO:0034038 deoxyhypusine synthase activity. +synonym: "(4-aminobutyl)lysine synthase activity" RELATED [EC:2.5.1.46] +synonym: "[eIF-5A]-deoxyhypusine synthase activity" RELATED [EC:2.5.1.46] +synonym: "deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase" EXACT [] +synonym: "deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase" EXACT [] +synonym: "deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase" EXACT [] +synonym: "deoxyhypusine formation from spermidine, using deoxyhypusine synthase" EXACT [] +synonym: "spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase" EXACT [] +synonym: "spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase" EXACT [] +synonym: "spermidine degradation to deoxyhypusine, using deoxyhypusine synthase" EXACT [] +xref: EC:2.5.1.46 +xref: MetaCyc:2.5.1.46-RXN +is_obsolete: true +consider: GO:0034038 + +[Term] +id: GO:0050984 +name: peptidyl-serine sulfation +namespace: biological_process +def: "The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine." [RESID:AA0361] +xref: RESID:AA0361 +is_a: GO:0006477 ! protein sulfation +is_a: GO:0018209 ! peptidyl-serine modification + +[Term] +id: GO:0050985 +name: peptidyl-threonine sulfation +namespace: biological_process +def: "The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine." [RESID:AA0362] +xref: RESID:AA0362 +is_a: GO:0006477 ! protein sulfation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0050986 +name: isopeptide cross-linking via N-(L-isoglutamyl)-glycine +namespace: biological_process +def: "The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25." [PMID:14531691, RESID:AA0360] +xref: RESID:AA0360 +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018262 ! isopeptide cross-linking + +[Term] +id: GO:0050987 +name: enzyme active site formation via O-sulfo-L-serine +namespace: biological_process +def: "The transient sulfation of peptidyl-serine to form O-sulfo-L-serine." [RESID:AA0361] +xref: RESID:AA0361 +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0050984 ! peptidyl-serine sulfation + +[Term] +id: GO:0050988 +name: N-terminal peptidyl-methionine carboxylation +namespace: biological_process +def: "The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine." [RESID:AA0363] +xref: RESID:AA0363 +is_a: GO:0018206 ! peptidyl-methionine modification +is_a: GO:0050989 ! N-terminal protein amino acid carboxylation + +[Term] +id: GO:0050989 +name: N-terminal protein amino acid carboxylation +namespace: biological_process +def: "The carboxylation of the N-terminal amino acid of proteins." [GOC:ai] +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0050990 +name: N-terminal protein amino acid carbamoylation +namespace: biological_process +def: "The carbamoylation of the N-terminal amino acid of proteins." [GOC:ai] +synonym: "N-terminal protein amino acid carbamylation" EXACT [] +is_a: GO:0031365 ! N-terminal protein amino acid modification + +[Term] +id: GO:0050991 +name: enzyme active site formation via O-sulfo-L-threonine +namespace: biological_process +def: "The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine." [RESID:AA0362] +xref: RESID:AA0362 +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0050985 ! peptidyl-threonine sulfation + +[Term] +id: GO:0050992 +name: dimethylallyl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate." [GOC:ai] +synonym: "dimethylallyl diphosphate anabolism" EXACT [] +synonym: "dimethylallyl diphosphate biosynthesis" EXACT [] +synonym: "dimethylallyl diphosphate formation" EXACT [] +synonym: "dimethylallyl diphosphate synthesis" EXACT [] +synonym: "dimethylallyl pyrophosphate biosynthesis" EXACT [] +synonym: "dimethylallyl pyrophosphate biosynthetic process" EXACT [] +synonym: "DPP biosynthesis" EXACT [] +synonym: "DPP biosynthetic process" EXACT [] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0050993 ! dimethylallyl diphosphate metabolic process + +[Term] +id: GO:0050993 +name: dimethylallyl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dimethylallyl diphosphate." [GOC:ai] +synonym: "dimethylallyl diphosphate metabolism" EXACT [] +synonym: "dimethylallyl pyrophosphate metabolic process" EXACT [] +synonym: "dimethylallyl pyrophosphate metabolism" EXACT [] +synonym: "DPP metabolic process" EXACT [] +synonym: "DPP metabolism" EXACT [] +is_a: GO:0006644 ! phospholipid metabolic process + +[Term] +id: GO:0050994 +name: regulation of lipid catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] +synonym: "regulation of lipid breakdown" EXACT [] +synonym: "regulation of lipid catabolism" EXACT [] +synonym: "regulation of lipid degradation" EXACT [] +is_a: GO:0009894 ! regulation of catabolic process +is_a: GO:0019216 ! regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016042 ! lipid catabolic process +relationship: regulates GO:0016042 ! lipid catabolic process + +[Term] +id: GO:0050995 +name: negative regulation of lipid catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] +synonym: "down regulation of lipid catabolic process" EXACT [] +synonym: "down-regulation of lipid catabolic process" EXACT [] +synonym: "downregulation of lipid catabolic process" EXACT [] +synonym: "inhibition of lipid catabolic process" NARROW [] +synonym: "negative regulation of lipid breakdown" EXACT [] +synonym: "negative regulation of lipid catabolism" EXACT [] +synonym: "negative regulation of lipid degradation" EXACT [] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016042 ! lipid catabolic process +relationship: negatively_regulates GO:0016042 ! lipid catabolic process + +[Term] +id: GO:0050996 +name: positive regulation of lipid catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] +synonym: "activation of lipid catabolic process" NARROW [] +synonym: "positive regulation of lipid breakdown" EXACT [] +synonym: "positive regulation of lipid catabolism" EXACT [] +synonym: "positive regulation of lipid degradation" EXACT [] +synonym: "stimulation of lipid catabolic process" NARROW [] +synonym: "up regulation of lipid catabolic process" EXACT [] +synonym: "up-regulation of lipid catabolic process" EXACT [] +synonym: "upregulation of lipid catabolic process" EXACT [] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016042 ! lipid catabolic process +relationship: positively_regulates GO:0016042 ! lipid catabolic process + +[Term] +id: GO:0050997 +name: quaternary ammonium group binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups." [GOC:ai] +synonym: "quaternary amine binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0050998 +name: nitric-oxide synthase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme nitric-oxide synthase." [GOC:ai] +synonym: "NOS binding" EXACT [] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0050999 +name: regulation of nitric-oxide synthase activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme nitric-oxide synthase." [GOC:ai] +synonym: "nitric-oxide synthase regulator" EXACT [] +synonym: "NOS regulator" EXACT [] +synonym: "regulation of NOS activity" EXACT [] +is_a: GO:0032768 ! regulation of monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004517 ! nitric-oxide synthase activity +relationship: regulates GO:0004517 ! nitric-oxide synthase activity + +[Term] +id: GO:0051000 +name: positive regulation of nitric-oxide synthase activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme nitric-oxide synthase." [GOC:ai] +synonym: "activation of nitric-oxide synthase activity" NARROW [] +synonym: "nitric-oxide synthase activator" EXACT [] +synonym: "NOS activator" EXACT [] +synonym: "positive regulation of NOS activity" EXACT [] +synonym: "stimulation of nitric-oxide synthase activity" NARROW [] +synonym: "up regulation of nitric-oxide synthase activity" EXACT [] +synonym: "up-regulation of nitric-oxide synthase activity" EXACT [] +synonym: "upregulation of nitric-oxide synthase activity" EXACT [] +is_a: GO:0032770 ! positive regulation of monooxygenase activity +is_a: GO:0050999 ! regulation of nitric-oxide synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004517 ! nitric-oxide synthase activity +relationship: positively_regulates GO:0004517 ! nitric-oxide synthase activity + +[Term] +id: GO:0051001 +name: negative regulation of nitric-oxide synthase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme nitric-oxide synthase." [GOC:ai] +synonym: "down regulation of nitric-oxide synthase activity" EXACT [] +synonym: "down-regulation of nitric-oxide synthase activity" EXACT [] +synonym: "downregulation of nitric-oxide synthase activity" EXACT [] +synonym: "inhibition of nitric-oxide synthase activity" NARROW [] +synonym: "negative regulation of NOS activity" EXACT [] +synonym: "nitric-oxide synthase inhibitor" NARROW [] +synonym: "NOS inhibitor" NARROW [] +is_a: GO:0032769 ! negative regulation of monooxygenase activity +is_a: GO:0050999 ! regulation of nitric-oxide synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004517 ! nitric-oxide synthase activity +relationship: negatively_regulates GO:0004517 ! nitric-oxide synthase activity + +[Term] +id: GO:0051002 +name: ligase activity, forming nitrogen-metal bonds +namespace: molecular_function +def: "Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6.6, GOC:mah] +xref: EC:6.6 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0051003 +name: ligase activity, forming nitrogen-metal bonds, forming coordination complexes +namespace: molecular_function +def: "Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex." [EC:6.6.1.-] +xref: EC:6.6.1 +is_a: GO:0051002 ! ligase activity, forming nitrogen-metal bonds + +[Term] +id: GO:0051004 +name: regulation of lipoprotein lipase activity +namespace: biological_process +def: "Any process that modulates the activity of the enzyme lipoprotein lipase." [GOC:ai] +is_a: GO:0060191 ! regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004465 ! lipoprotein lipase activity +relationship: regulates GO:0004465 ! lipoprotein lipase activity + +[Term] +id: GO:0051005 +name: negative regulation of lipoprotein lipase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme lipoprotein lipase." [GOC:ai] +synonym: "down regulation of lipoprotein lipase activity" EXACT [] +synonym: "down-regulation of lipoprotein lipase activity" EXACT [] +synonym: "downregulation of lipoprotein lipase activity" EXACT [] +synonym: "inhibition of lipoprotein lipase activity" NARROW [] +is_a: GO:0051004 ! regulation of lipoprotein lipase activity +is_a: GO:0060192 ! negative regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004465 ! lipoprotein lipase activity +relationship: negatively_regulates GO:0004465 ! lipoprotein lipase activity + +[Term] +id: GO:0051006 +name: positive regulation of lipoprotein lipase activity +namespace: biological_process +def: "Any process that activates or increases the activity of the enzyme lipoprotein lipase." [GOC:ai] +synonym: "activation of lipoprotein lipase activity" NARROW [] +synonym: "stimulation of lipoprotein lipase activity" NARROW [] +synonym: "up regulation of lipoprotein lipase activity" EXACT [] +synonym: "up-regulation of lipoprotein lipase activity" EXACT [] +synonym: "upregulation of lipoprotein lipase activity" EXACT [] +is_a: GO:0051004 ! regulation of lipoprotein lipase activity +is_a: GO:0061365 ! positive regulation of triglyceride lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004465 ! lipoprotein lipase activity +relationship: positively_regulates GO:0004465 ! lipoprotein lipase activity + +[Term] +id: GO:0051007 +name: squalene-hopene cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: squalene = hop-22(29)-ene." [EC:5.4.99.17] +synonym: "squalene mutase (cyclizing)" EXACT [EC:5.4.99.17] +synonym: "squalene:hopene cyclase activity" EXACT [PMID:18033581] +xref: EC:5.4.99.17 +xref: MetaCyc:5.4.99.17-RXN +is_a: GO:0016866 ! intramolecular transferase activity +is_a: GO:0034072 ! squalene cyclase activity + +[Term] +id: GO:0051008 +name: Hsp27 protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Hsp27 proteins, a lightweight heat shock protein." [GOC:ai] +is_a: GO:0031072 ! heat shock protein binding + +[Term] +id: GO:0051009 +name: O-acetylhomoserine sulfhydrylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate." [MetaCyc:ACETYLHOMOSER-CYS-RXN, RHEA:27822] +xref: MetaCyc:ACETYLHOMOSER-CYS-RXN +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0051010 +name: microtubule plus-end binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the plus end of a microtubule." [GOC:ai, PMID:14557818, PMID:14614826] +is_a: GO:0008017 ! microtubule binding + +[Term] +id: GO:0051011 +name: microtubule minus-end binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the minus end of a microtubule." [GOC:ai, PMID:14557818, PMID:14614826] +is_a: GO:0008017 ! microtubule binding + +[Term] +id: GO:0051012 +name: microtubule sliding +namespace: biological_process +def: "The movement of one microtubule along another microtubule." [PMID:14557818, PMID:14614826] +synonym: "microtubule translocation" EXACT [] +is_a: GO:0007018 ! microtubule-based movement + +[Term] +id: GO:0051013 +name: microtubule severing +namespace: biological_process +def: "The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends." [GOC:ai, PMID:27037673] +synonym: "microtubule severing activity" RELATED [] +is_a: GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0051014 +name: actin filament severing +namespace: biological_process +def: "The process in which an actin filament is broken down into smaller filaments." [GOC:ai, PMID:14657234] +synonym: "actin filament severing activity" RELATED [] +synonym: "barbed-end actin capping/severing activity" RELATED [] +synonym: "F-actin severing" EXACT [] +is_a: GO:0030029 ! actin filament-based process + +[Term] +id: GO:0051015 +name: actin filament binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits." [ISBN:0198506732] +synonym: "actin cross-linking activity" RELATED [] +synonym: "F-actin binding" EXACT [] +is_a: GO:0003779 ! actin binding +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0051016 +name: barbed-end actin filament capping +namespace: biological_process +def: "The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] +synonym: "barbed-end actin capping activity" EXACT [] +synonym: "barbed-end F-actin capping activity" EXACT [] +synonym: "plus-end actin filament capping activity" EXACT [] +synonym: "plus-end F-actin capping activity" EXACT [] +is_a: GO:0051693 ! actin filament capping + +[Term] +id: GO:0051017 +name: actin filament bundle assembly +namespace: biological_process +alt_id: GO:0045011 +def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai] +synonym: "actin bundling activity" RELATED [] +synonym: "actin cable assembly" RELATED [GOC:mah] +synonym: "actin cable formation" RELATED [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0061572 ! actin filament bundle organization + +[Term] +id: GO:0051018 +name: protein kinase A binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any subunit of protein kinase A." [GOC:ai] +comment: Note that this term is a direct child of 'protein binding ; GO:0005515' because it encompasses binding to either the catalytic or regulatory subunit of protein kinase A, and the latter does not have kinase activity. +synonym: "PKA binding" EXACT [] +synonym: "protein kinase A anchoring activity" RELATED [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051019 +name: mitogen-activated protein kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitogen-activated protein kinase." [GOC:ai] +synonym: "MAP kinase binding" EXACT [] +synonym: "MAP-kinase anchoring activity" RELATED [] +synonym: "MAPK binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding + +[Term] +id: GO:0051020 +name: GTPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP." [GOC:ai] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0051021 +name: GDP-dissociation inhibitor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a GDP-dissociation inhibitor protein." [GOC:ai] +synonym: "GDI binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051022 +name: Rho GDP-dissociation inhibitor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein." [GOC:ai] +synonym: "Rho GDI binding" EXACT [] +is_a: GO:0051021 ! GDP-dissociation inhibitor binding + +[Term] +id: GO:0051023 +name: regulation of immunoglobulin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell." [GOC:ai] +synonym: "regulation of antibody secretion" EXACT [] +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048305 ! immunoglobulin secretion +relationship: regulates GO:0048305 ! immunoglobulin secretion + +[Term] +id: GO:0051024 +name: positive regulation of immunoglobulin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell." [GOC:ai] +synonym: "activation of immunoglobulin secretion" NARROW [] +synonym: "positive regulation of antibody secretion" EXACT [] +synonym: "stimulation of immunoglobulin secretion" NARROW [] +synonym: "up regulation of immunoglobulin secretion" EXACT [] +synonym: "up-regulation of immunoglobulin secretion" EXACT [] +synonym: "upregulation of immunoglobulin secretion" EXACT [] +is_a: GO:0002639 ! positive regulation of immunoglobulin production +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0051023 ! regulation of immunoglobulin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048305 ! immunoglobulin secretion +relationship: positively_regulates GO:0048305 ! immunoglobulin secretion + +[Term] +id: GO:0051025 +name: negative regulation of immunoglobulin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of immunoglobulins from a cell." [GOC:ai] +synonym: "down regulation of immunoglobulin secretion" EXACT [] +synonym: "down-regulation of immunoglobulin secretion" EXACT [] +synonym: "downregulation of immunoglobulin secretion" EXACT [] +synonym: "inhibition of immunoglobulin secretion" NARROW [] +synonym: "negative regulation of antibody secretion" EXACT [] +is_a: GO:0002638 ! negative regulation of immunoglobulin production +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0051023 ! regulation of immunoglobulin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048305 ! immunoglobulin secretion +relationship: negatively_regulates GO:0048305 ! immunoglobulin secretion + +[Term] +id: GO:0051026 +name: chiasma assembly +namespace: biological_process +def: "The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids." [PMID:23396135] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007129 ! synapsis +relationship: part_of GO:0007131 ! reciprocal meiotic recombination + +[Term] +id: GO:0051027 +name: DNA transport +namespace: biological_process +def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050657 ! nucleic acid transport + +[Term] +id: GO:0051028 +name: mRNA transport +namespace: biological_process +def: "The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050658 ! RNA transport + +[Term] +id: GO:0051029 +name: rRNA transport +namespace: biological_process +def: "The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050658 ! RNA transport + +[Term] +id: GO:0051030 +name: snRNA transport +namespace: biological_process +def: "The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050658 ! RNA transport + +[Term] +id: GO:0051031 +name: tRNA transport +namespace: biological_process +def: "The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0050658 ! RNA transport + +[Term] +id: GO:0051032 +name: nucleic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] +is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity +is_a: GO:0022884 ! macromolecule transmembrane transporter activity +relationship: part_of GO:0050657 ! nucleic acid transport + +[Term] +id: GO:0051033 +name: RNA transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] +xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" +is_a: GO:0051032 ! nucleic acid transmembrane transporter activity +relationship: part_of GO:0050658 ! RNA transport + +[Term] +id: GO:0051034 +name: tRNA transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0051033 ! RNA transmembrane transporter activity +relationship: part_of GO:0051031 ! tRNA transport + +[Term] +id: GO:0051035 +name: DNA transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] +is_a: GO:0051032 ! nucleic acid transmembrane transporter activity +relationship: part_of GO:0051027 ! DNA transport + +[Term] +id: GO:0051036 +name: regulation of endosome size +namespace: biological_process +def: "Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis." [GOC:ai] +synonym: "endosome enlargement" RELATED [] +is_a: GO:0097494 ! regulation of vesicle size + +[Term] +id: GO:0051037 +name: regulation of transcription involved in meiotic cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle." [GOC:go_curators] +synonym: "meiotic regulation of transcription" EXACT [] +synonym: "regulation of transcription, meiotic" EXACT [GOC:mah] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051038 +name: negative regulation of transcription involved in meiotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle." [GOC:ai] +synonym: "down regulation of transcription during meiosis" EXACT [GOC:mah] +synonym: "down-regulation of transcription during meiosis" EXACT [GOC:mah] +synonym: "downregulation of transcription during meiosis" EXACT [GOC:mah] +synonym: "inhibition of transcription during meiosis" NARROW [GOC:mah] +synonym: "meiotic repression of transcription" EXACT [] +synonym: "negative regulation of meiotic transcription" EXACT [] +synonym: "negative regulation of transcription, meiotic" EXACT [GOC:mah] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:0051037 ! regulation of transcription involved in meiotic cell cycle +intersection_of: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051039 +name: positive regulation of transcription involved in meiotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle." [GOC:ai] +synonym: "activation of transcription during meiosis" NARROW [GOC:mah] +synonym: "positive regulation of meiotic transcription" EXACT [] +synonym: "positive regulation of transcription, meiotic" EXACT [GOC:mah] +synonym: "stimulation of transcription during meiosis" NARROW [GOC:mah] +synonym: "up regulation of transcription during meiosis" EXACT [GOC:mah] +synonym: "up-regulation of transcription during meiosis" EXACT [GOC:mah] +synonym: "upregulation of transcription during meiosis" EXACT [GOC:mah] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:0051037 ! regulation of transcription involved in meiotic cell cycle +intersection_of: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051040 +name: regulation of calcium-independent cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction." [GOC:ai] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules +relationship: regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules + +[Term] +id: GO:0051041 +name: positive regulation of calcium-independent cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion." [GOC:ai] +synonym: "activation of calcium-independent cell-cell adhesion" NARROW [] +synonym: "stimulation of calcium-independent cell-cell adhesion" NARROW [] +synonym: "up regulation of calcium-independent cell-cell adhesion" EXACT [] +synonym: "up-regulation of calcium-independent cell-cell adhesion" EXACT [] +synonym: "upregulation of calcium-independent cell-cell adhesion" EXACT [] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0051040 ! regulation of calcium-independent cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules +relationship: positively_regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules + +[Term] +id: GO:0051042 +name: negative regulation of calcium-independent cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion." [GOC:ai] +synonym: "down regulation of calcium-independent cell-cell adhesion" EXACT [] +synonym: "down-regulation of calcium-independent cell-cell adhesion" EXACT [] +synonym: "downregulation of calcium-independent cell-cell adhesion" EXACT [] +synonym: "inhibition of calcium-independent cell-cell adhesion" NARROW [] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0051040 ! regulation of calcium-independent cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules +relationship: negatively_regulates GO:0016338 ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules + +[Term] +id: GO:0051043 +name: regulation of membrane protein ectodomain proteolysis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)." [GOC:ai] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0042176 ! regulation of protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006509 ! membrane protein ectodomain proteolysis +relationship: regulates GO:0006509 ! membrane protein ectodomain proteolysis + +[Term] +id: GO:0051044 +name: positive regulation of membrane protein ectodomain proteolysis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis." [GOC:ai] +synonym: "activation of membrane protein ectodomain proteolysis" NARROW [] +synonym: "stimulation of membrane protein ectodomain proteolysis" NARROW [] +synonym: "up regulation of membrane protein ectodomain proteolysis" EXACT [] +synonym: "up-regulation of membrane protein ectodomain proteolysis" EXACT [] +synonym: "upregulation of membrane protein ectodomain proteolysis" EXACT [] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045732 ! positive regulation of protein catabolic process +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:0051043 ! regulation of membrane protein ectodomain proteolysis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006509 ! membrane protein ectodomain proteolysis +relationship: positively_regulates GO:0006509 ! membrane protein ectodomain proteolysis + +[Term] +id: GO:0051045 +name: negative regulation of membrane protein ectodomain proteolysis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis." [GOC:ai] +synonym: "down regulation of membrane protein ectodomain proteolysis" EXACT [] +synonym: "down-regulation of membrane protein ectodomain proteolysis" EXACT [] +synonym: "downregulation of membrane protein ectodomain proteolysis" EXACT [] +synonym: "inhibition of membrane protein ectodomain proteolysis" NARROW [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0042177 ! negative regulation of protein catabolic process +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:0051043 ! regulation of membrane protein ectodomain proteolysis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006509 ! membrane protein ectodomain proteolysis +relationship: negatively_regulates GO:0006509 ! membrane protein ectodomain proteolysis + +[Term] +id: GO:0051046 +name: regulation of secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046903 ! secretion +relationship: regulates GO:0046903 ! secretion + +[Term] +id: GO:0051047 +name: positive regulation of secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] +synonym: "activation of secretion" NARROW [] +synonym: "stimulation of secretion" NARROW [] +synonym: "up regulation of secretion" EXACT [] +synonym: "up-regulation of secretion" EXACT [] +synonym: "upregulation of secretion" EXACT [] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0051050 ! positive regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046903 ! secretion +relationship: positively_regulates GO:0046903 ! secretion + +[Term] +id: GO:0051048 +name: negative regulation of secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] +synonym: "down regulation of secretion" EXACT [] +synonym: "down-regulation of secretion" EXACT [] +synonym: "downregulation of secretion" EXACT [] +synonym: "inhibition of secretion" NARROW [] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0051051 ! negative regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046903 ! secretion +relationship: negatively_regulates GO:0046903 ! secretion + +[Term] +id: GO:0051049 +name: regulation of transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +subset: goslim_yeast +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006810 ! transport +relationship: regulates GO:0006810 ! transport + +[Term] +id: GO:0051050 +name: positive regulation of transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of transport" NARROW [] +synonym: "stimulation of transport" NARROW [] +synonym: "up regulation of transport" EXACT [] +synonym: "up-regulation of transport" EXACT [] +synonym: "upregulation of transport" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006810 ! transport +relationship: positively_regulates GO:0006810 ! transport + +[Term] +id: GO:0051051 +name: negative regulation of transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of transport" EXACT [] +synonym: "down-regulation of transport" EXACT [] +synonym: "downregulation of transport" EXACT [] +synonym: "inhibition of transport" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006810 ! transport +relationship: negatively_regulates GO:0006810 ! transport + +[Term] +id: GO:0051052 +name: regulation of DNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] +subset: goslim_yeast +synonym: "regulation of DNA metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006259 ! DNA metabolic process +relationship: regulates GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0051053 +name: negative regulation of DNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] +synonym: "down regulation of DNA metabolic process" EXACT [] +synonym: "down-regulation of DNA metabolic process" EXACT [] +synonym: "downregulation of DNA metabolic process" EXACT [] +synonym: "inhibition of DNA metabolic process" NARROW [] +synonym: "negative regulation of DNA metabolism" EXACT [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006259 ! DNA metabolic process +relationship: negatively_regulates GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0051054 +name: positive regulation of DNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] +synonym: "activation of DNA metabolic process" NARROW [] +synonym: "positive regulation of DNA metabolism" EXACT [] +synonym: "stimulation of DNA metabolic process" NARROW [] +synonym: "up regulation of DNA metabolic process" EXACT [] +synonym: "up-regulation of DNA metabolic process" EXACT [] +synonym: "upregulation of DNA metabolic process" EXACT [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006259 ! DNA metabolic process +relationship: positively_regulates GO:0006259 ! DNA metabolic process + +[Term] +id: GO:0051055 +name: negative regulation of lipid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] +synonym: "down regulation of lipid biosynthetic process" EXACT [] +synonym: "down-regulation of lipid biosynthetic process" EXACT [] +synonym: "downregulation of lipid biosynthetic process" EXACT [] +synonym: "inhibition of lipid biosynthetic process" NARROW [] +synonym: "negative regulation of lipid anabolism" EXACT [] +synonym: "negative regulation of lipid biosynthesis" EXACT [] +synonym: "negative regulation of lipid formation" EXACT [] +synonym: "negative regulation of lipid synthesis" EXACT [] +synonym: "negative regulation of lipogenesis" EXACT [GOC:sl] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008610 ! lipid biosynthetic process +relationship: negatively_regulates GO:0008610 ! lipid biosynthetic process + +[Term] +id: GO:0051056 +name: regulation of small GTPase mediated signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:go_curators] +synonym: "regulation of small GTPase-mediated signal transduction" EXACT [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007264 ! small GTPase mediated signal transduction +relationship: regulates GO:0007264 ! small GTPase mediated signal transduction + +[Term] +id: GO:0051057 +name: positive regulation of small GTPase mediated signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:ai] +synonym: "activation of small GTPase mediated signal transduction" NARROW [] +synonym: "positive regulation of small GTPase-mediated signal transduction" EXACT [] +synonym: "stimulation of small GTPase mediated signal transduction" NARROW [] +synonym: "up regulation of small GTPase mediated signal transduction" EXACT [] +synonym: "up-regulation of small GTPase mediated signal transduction" EXACT [] +synonym: "upregulation of small GTPase mediated signal transduction" EXACT [] +is_a: GO:0051056 ! regulation of small GTPase mediated signal transduction +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007264 ! small GTPase mediated signal transduction +relationship: positively_regulates GO:0007264 ! small GTPase mediated signal transduction + +[Term] +id: GO:0051058 +name: negative regulation of small GTPase mediated signal transduction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:ai] +synonym: "down regulation of small GTPase mediated signal transduction" EXACT [] +synonym: "down-regulation of small GTPase mediated signal transduction" EXACT [] +synonym: "downregulation of small GTPase mediated signal transduction" EXACT [] +synonym: "inhibition of small GTPase mediated signal transduction" NARROW [] +synonym: "negative regulation of small GTPase-mediated signal transduction" EXACT [] +is_a: GO:0051056 ! regulation of small GTPase mediated signal transduction +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007264 ! small GTPase mediated signal transduction +relationship: negatively_regulates GO:0007264 ! small GTPase mediated signal transduction + +[Term] +id: GO:0051059 +name: NF-kappaB binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters." [GOC:ai] +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding + +[Term] +id: GO:0051060 +name: pullulanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen." [EC:3.2.1.41] +synonym: "alpha-dextrin endo-1,6-alpha-glucosidase activity" EXACT [] +synonym: "amylopectin 6-glucanohydrolase activity" EXACT [] +synonym: "bacterial debranching enzyme" RELATED [EC:3.2.1.41] +synonym: "debranching enzyme activity" BROAD [EC:3.2.1.41] +synonym: "limit dextrinase" RELATED [] +synonym: "pullulan 6-glucanohydrolase activity" EXACT [] +synonym: "pullulan alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.41] +synonym: "R-enzyme" RELATED [EC:3.2.1.41] +xref: EC:3.2.1.41 +xref: MetaCyc:RXN-1824 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0051061 +name: ADP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin." [MetaCyc:ADPREDUCT-RXN] +synonym: "ADP reduction" RELATED [] +xref: MetaCyc:ADPREDUCT-RXN +is_a: GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor + +[Term] +id: GO:0051062 +name: UDP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin." [MetaCyc:UDPREDUCT-RXN] +synonym: "UDP reduction" RELATED [] +xref: MetaCyc:UDPREDUCT-RXN +is_a: GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor + +[Term] +id: GO:0051063 +name: CDP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin." [MetaCyc:CDPREDUCT-RXN] +synonym: "CDP reduction" RELATED [] +xref: MetaCyc:CDPREDUCT-RXN +is_a: GO:0004748 ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor + +[Term] +id: GO:0051064 +name: TTP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [MetaCyc:1.17.4.2-RXN] +synonym: "TTP reduction" RELATED [] +xref: EC:1.17.4 +is_a: GO:0008998 ! ribonucleoside-triphosphate reductase activity + +[Term] +id: GO:0051065 +name: CTP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [MetaCyc:1.17.4.2-RXN] +synonym: "CTP reduction" RELATED [] +xref: EC:1.17.4 +is_a: GO:0008998 ! ribonucleoside-triphosphate reductase activity + +[Term] +id: GO:0051066 +name: dihydrobiopterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions." [PMID:2557335] +synonym: "6,7-dihydrobiopterin metabolic process" NARROW [CHEBI:20680] +synonym: "7,8-dihydrobiopterin metabolic process" NARROW [CHEBI:15375] +synonym: "dihydrobiopterin reduction" NARROW [] +synonym: "dihydropterin metabolic process" EXACT [CHEBI:38797] +synonym: "dihydropterin metabolism" EXACT [] +is_a: GO:0042558 ! pteridine-containing compound metabolic process + +[Term] +id: GO:0051067 +name: dihydropteridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4." [PMID:2557335] +synonym: "6,7-dihydropteridine metabolic process" EXACT [PMID:19567870] +synonym: "dihydropteridine metabolism" EXACT [] +synonym: "dihydropteridine reduction" NARROW [] +is_a: GO:0042558 ! pteridine-containing compound metabolic process + +[Term] +id: GO:0051068 +name: dihydrolipoamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor." [ISBN:0721601464] +synonym: "dihydrolipoamide metabolism" EXACT [] +synonym: "dihydrolipoamide reduction" NARROW [] +synonym: "dihydrothioctamide metabolic process" EXACT [] +synonym: "dihydrothioctamide metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0051069 +name: galactomannan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units." [http://www.els.net/els/public/glossary/] +synonym: "galactomannan metabolism" EXACT [] +is_a: GO:0006080 ! substituted mannan metabolic process + +[Term] +id: GO:0051070 +name: galactomannan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units." [GOC:ai] +synonym: "galactomannan anabolism" EXACT [] +synonym: "galactomannan biosynthesis" EXACT [] +synonym: "galactomannan formation" EXACT [] +synonym: "galactomannan synthesis" EXACT [] +is_a: GO:0000271 ! polysaccharide biosynthetic process +is_a: GO:0051069 ! galactomannan metabolic process + +[Term] +id: GO:0051071 +name: 4,6-pyruvylated galactose residue metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain." [GOC:ai, PMID:15173185] +synonym: "4,6-pyruvylated galactose residue metabolism" EXACT [] +synonym: "4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolic process" EXACT [] +synonym: "4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolism" EXACT [] +synonym: "PvGal metabolic process" EXACT [] +synonym: "PvGal metabolism" EXACT [] +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0051072 +name: 4,6-pyruvylated galactose residue biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain." [GOC:ai, PMID:15173185] +synonym: "4,6-pyruvylated galactose residue anabolism" EXACT [] +synonym: "4,6-pyruvylated galactose residue biosynthesis" EXACT [] +synonym: "4,6-pyruvylated galactose residue formation" EXACT [] +synonym: "4,6-pyruvylated galactose residue synthesis" EXACT [] +synonym: "4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthesis" EXACT [] +synonym: "4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthetic process" EXACT [] +synonym: "PvGal biosynthesis" EXACT [] +synonym: "PvGal biosynthetic process" EXACT [] +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process + +[Term] +id: GO:0051073 +name: adenosylcobinamide-GDP ribazoletransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin." [EC:2.7.8.26, MetaCyc:COBALAMINSYN-RXN] +synonym: "adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity" EXACT [EC:2.7.8.26] +synonym: "cobalamin (5'-phosphate) synthase activity" EXACT [EC:2.7.8.26] +synonym: "cobalamin synthase activity" EXACT [] +synonym: "cobalamin-5'-phosphate synthase activity" EXACT [EC:2.7.8.26] +synonym: "CobS" RELATED [EC:2.7.8.26] +xref: EC:2.7.8.26 +xref: MetaCyc:COBALAMINSYN-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0051074 +name: obsolete protein tetramerization activity +namespace: molecular_function +def: "OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits." [GOC:ecd] +comment: This term was made obsolete because it represents a process. +synonym: "protein tetramerization activity" EXACT [] +is_obsolete: true +replaced_by: GO:0051262 + +[Term] +id: GO:0051075 +name: S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA." [PMID:12731872] +synonym: "S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity" EXACT [] +is_a: GO:0016740 ! transferase activity +is_a: GO:0016853 ! isomerase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0051077 +name: secondary cell septum +namespace: cellular_component +def: "Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum." [GOC:mtg_sensu, PMID:15194814] +synonym: "secondary septum" BROAD [] +is_a: GO:0000935 ! division septum + +[Term] +id: GO:0051078 +name: meiotic nuclear envelope disassembly +namespace: biological_process +def: "The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs." [GOC:bf] +synonym: "meiotic nuclear envelope breakdown" EXACT [] +synonym: "meiotic nuclear envelope catabolism" EXACT [] +synonym: "meiotic nuclear envelope degradation" EXACT [] +is_a: GO:0051081 ! nuclear envelope disassembly +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051081 ! nuclear envelope disassembly +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051079 +name: meiosis I nuclear envelope disassembly +namespace: biological_process +def: "The controlled breakdown of the nuclear envelope during the first division of meiosis." [GOC:bf] +synonym: "meiosis I nuclear envelope breakdown" EXACT [] +synonym: "meiosis I nuclear envelope catabolism" EXACT [] +synonym: "meiosis I nuclear envelope degradation" EXACT [] +is_a: GO:0051078 ! meiotic nuclear envelope disassembly +intersection_of: GO:0051081 ! nuclear envelope disassembly +intersection_of: part_of GO:0007127 ! meiosis I +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0051080 +name: meiosis II nuclear envelope disassembly +namespace: biological_process +def: "The controlled breakdown of the nuclear envelope during the second division of meiosis." [GOC:bf] +synonym: "meiosis II nuclear envelope breakdown" EXACT [] +synonym: "meiosis II nuclear envelope catabolism" EXACT [] +synonym: "meiosis II nuclear envelope degradation" EXACT [] +is_a: GO:0051078 ! meiotic nuclear envelope disassembly +intersection_of: GO:0051081 ! nuclear envelope disassembly +intersection_of: part_of GO:0007135 ! meiosis II +relationship: part_of GO:0007135 ! meiosis II + +[Term] +id: GO:0051081 +name: nuclear envelope disassembly +namespace: biological_process +def: "The controlled breakdown of the nuclear envelope in the context of a normal process." [GOC:ai] +synonym: "nuclear envelope breakdown" EXACT [] +synonym: "nuclear envelope catabolism" EXACT [] +synonym: "nuclear envelope degradation" EXACT [] +is_a: GO:0006998 ! nuclear envelope organization +is_a: GO:0030397 ! membrane disassembly + +[Term] +id: GO:0051082 +name: unfolded protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an unfolded protein." [GOC:ai] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_yeast +synonym: "binding unfolded ER proteins" NARROW [] +synonym: "chaperone activity" RELATED [] +synonym: "fimbrium-specific chaperone activity" NARROW [] +synonym: "glycoprotein-specific chaperone activity" NARROW [] +synonym: "histone-specific chaperone activity" NARROW [] +synonym: "ribosomal chaperone activity" NARROW [] +synonym: "tubulin-specific chaperone activity" NARROW [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051083 +name: 'de novo' cotranslational protein folding +namespace: biological_process +alt_id: GO:0006444 +def: "The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated." [GOC:rb] +synonym: "'de novo' co-translational protein folding" EXACT [] +synonym: "multidomain protein assembly" EXACT [] +synonym: "nascent polypeptide association" EXACT [] +is_a: GO:0006458 ! 'de novo' protein folding + +[Term] +id: GO:0051084 +name: 'de novo' posttranslational protein folding +namespace: biological_process +def: "The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis." [GOC:rb] +synonym: "'de novo' post-translational protein folding" EXACT [] +is_a: GO:0006458 ! 'de novo' protein folding + +[Term] +id: GO:0051085 +name: chaperone cofactor-dependent protein refolding +namespace: biological_process +alt_id: GO:0070389 +def: "The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release." [GOC:rb] +synonym: "chaperone co-factor-dependent protein folding" RELATED [] +synonym: "chaperone co-factor-dependent protein refolding" EXACT [] +synonym: "chaperone cofactor-dependent 'de novo' protein folding" EXACT [GOC:mah] +synonym: "chaperone cofactor-dependent protein folding" EXACT [GOC:rb] +synonym: "chaperone mediated protein folding requiring cofactor" RELATED [] +is_a: GO:0051084 ! 'de novo' posttranslational protein folding +is_a: GO:0061077 ! chaperone-mediated protein folding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/10726 xsd:anyURI + +[Term] +id: GO:0051086 +name: chaperone mediated protein folding independent of cofactor +namespace: biological_process +def: "The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release." [GOC:rb] +synonym: "chaperone cofactor-independent protein folding" EXACT [GOC:rb] +is_a: GO:0051084 ! 'de novo' posttranslational protein folding +is_a: GO:0061077 ! chaperone-mediated protein folding + +[Term] +id: GO:0051087 +name: chaperone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport." [PMID:10585443] +synonym: "chaperone protein binding" EXACT [] +synonym: "co-chaperone activity" RELATED [] +synonym: "co-chaperonin activity" RELATED [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051088 +name: PMA-inducible membrane protein ectodomain proteolysis +namespace: biological_process +def: "The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist." [PMID:12714508] +is_a: GO:0006509 ! membrane protein ectodomain proteolysis + +[Term] +id: GO:0051089 +name: constitutive protein ectodomain proteolysis +namespace: biological_process +def: "The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands." [PMID:12714508] +is_a: GO:0006509 ! membrane protein ectodomain proteolysis + +[Term] +id: GO:0051090 +name: regulation of DNA-binding transcription factor activity +namespace: biological_process +alt_id: GO:1904167 +alt_id: GO:2000823 +def: "Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] +synonym: "regulation of androgen receptor activity" NARROW [] +synonym: "regulation of DNA binding transcription factor activity" EXACT [] +synonym: "regulation of sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "regulation of thyroid hormone receptor activity" NARROW [] +synonym: "regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0003700 ! DNA-binding transcription factor activity +relationship: regulates GO:0003700 ! DNA-binding transcription factor activity + +[Term] +id: GO:0051091 +name: positive regulation of DNA-binding transcription factor activity +namespace: biological_process +alt_id: GO:1904169 +def: "Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] +synonym: "activation of transcription factor activity" NARROW [] +synonym: "positive regulation of DNA binding transcription factor activity" EXACT [] +synonym: "positive regulation of sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "positive regulation of thyroid hormone receptor activity" NARROW [] +synonym: "positive regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] +synonym: "stimulation of transcription factor activity" NARROW [] +synonym: "up regulation of transcription factor activity" EXACT [] +synonym: "up-regulation of transcription factor activity" EXACT [] +synonym: "upregulation of transcription factor activity" EXACT [] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003700 ! DNA-binding transcription factor activity +relationship: positively_regulates GO:0003700 ! DNA-binding transcription factor activity +created_by: rph +creation_date: 2015-04-22T12:22:16Z + +[Term] +id: GO:0051092 +name: positive regulation of NF-kappaB transcription factor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030] +synonym: "activation of NF-kappaB" EXACT [] +synonym: "activation of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] +synonym: "NF-kappaB activation" EXACT [] +is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity + +[Term] +id: GO:0051093 +name: negative regulation of developmental process +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] +synonym: "down regulation of developmental process" EXACT [] +synonym: "down-regulation of developmental process" EXACT [] +synonym: "downregulation of developmental process" EXACT [] +synonym: "inhibition of developmental process" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032502 ! developmental process +relationship: negatively_regulates GO:0032502 ! developmental process + +[Term] +id: GO:0051094 +name: positive regulation of developmental process +namespace: biological_process +def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] +synonym: "activation of developmental process" NARROW [] +synonym: "stimulation of developmental process" NARROW [] +synonym: "up regulation of developmental process" EXACT [] +synonym: "up-regulation of developmental process" EXACT [] +synonym: "upregulation of developmental process" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032502 ! developmental process +relationship: positively_regulates GO:0032502 ! developmental process + +[Term] +id: GO:0051095 +name: regulation of helicase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of helicase activity." [GOC:ai] +is_a: GO:0043462 ! regulation of ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004386 ! helicase activity +relationship: regulates GO:0004386 ! helicase activity + +[Term] +id: GO:0051096 +name: positive regulation of helicase activity +namespace: biological_process +def: "Any process that activates or increases the activity of a helicase." [GOC:ai] +synonym: "activation of helicase activity" NARROW [] +synonym: "stimulation of helicase activity" NARROW [] +synonym: "up regulation of helicase activity" EXACT [] +synonym: "up-regulation of helicase activity" EXACT [] +synonym: "upregulation of helicase activity" EXACT [] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:0051095 ! regulation of helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004386 ! helicase activity +relationship: positively_regulates GO:0004386 ! helicase activity + +[Term] +id: GO:0051097 +name: negative regulation of helicase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of a helicase." [GOC:ai] +synonym: "down regulation of helicase activity" EXACT [] +synonym: "down-regulation of helicase activity" EXACT [] +synonym: "downregulation of helicase activity" EXACT [] +synonym: "inhibition of helicase activity" NARROW [] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:0051095 ! regulation of helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004386 ! helicase activity +relationship: negatively_regulates GO:0004386 ! helicase activity + +[Term] +id: GO:0051098 +name: regulation of binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005488 ! binding +relationship: regulates GO:0005488 ! binding + +[Term] +id: GO:0051099 +name: positive regulation of binding +namespace: biological_process +def: "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai] +synonym: "activation of binding" NARROW [] +synonym: "stimulation of binding" NARROW [] +synonym: "up regulation of binding" EXACT [] +synonym: "up-regulation of binding" EXACT [] +synonym: "upregulation of binding" EXACT [] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005488 ! binding +relationship: positively_regulates GO:0005488 ! binding + +[Term] +id: GO:0051100 +name: negative regulation of binding +namespace: biological_process +def: "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." [GOC:ai] +synonym: "down regulation of binding" EXACT [] +synonym: "down-regulation of binding" EXACT [] +synonym: "downregulation of binding" EXACT [] +synonym: "inhibition of binding" NARROW [] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005488 ! binding +relationship: negatively_regulates GO:0005488 ! binding + +[Term] +id: GO:0051101 +name: regulation of DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." [GOC:ai, GOC:dph, GOC:tb] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003677 ! DNA binding +relationship: regulates GO:0003677 ! DNA binding + +[Term] +id: GO:0051102 +name: DNA ligation involved in DNA recombination +namespace: biological_process +def: "The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination." [GOC:ai] +synonym: "DNA ligation during DNA recombination" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006266 ! DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0006310 ! DNA recombination +relationship: part_of GO:0006310 ! DNA recombination + +[Term] +id: GO:0051103 +name: DNA ligation involved in DNA repair +namespace: biological_process +def: "The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair." [GOC:ai] +synonym: "DNA ligation during DNA repair" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006266 ! DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0006281 ! DNA repair +relationship: part_of GO:0006281 ! DNA repair + +[Term] +id: GO:0051104 +name: DNA-dependent DNA replication DNA ligation +namespace: biological_process +def: "The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication." [GOC:ai, GOC:dph, GOC:tb] +synonym: "DNA ligation during DNA-dependent DNA replication" RELATED [GOC:dph, GOC:tb] +synonym: "DNA ligation involved in DNA-dependent DNA replication" EXACT [] +is_a: GO:0006266 ! DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0006261 ! DNA-dependent DNA replication +relationship: part_of GO:0006261 ! DNA-dependent DNA replication + +[Term] +id: GO:0051105 +name: regulation of DNA ligation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006266 ! DNA ligation +relationship: regulates GO:0006266 ! DNA ligation + +[Term] +id: GO:0051106 +name: positive regulation of DNA ligation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] +synonym: "activation of DNA ligation" NARROW [] +synonym: "stimulation of DNA ligation" NARROW [] +synonym: "up regulation of DNA ligation" EXACT [] +synonym: "up-regulation of DNA ligation" EXACT [] +synonym: "upregulation of DNA ligation" EXACT [] +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:0051105 ! regulation of DNA ligation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006266 ! DNA ligation +relationship: positively_regulates GO:0006266 ! DNA ligation + +[Term] +id: GO:0051107 +name: negative regulation of DNA ligation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] +synonym: "down regulation of DNA ligation" EXACT [] +synonym: "down-regulation of DNA ligation" EXACT [] +synonym: "downregulation of DNA ligation" EXACT [] +synonym: "inhibition of DNA ligation" NARROW [] +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:0051105 ! regulation of DNA ligation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006266 ! DNA ligation +relationship: negatively_regulates GO:0006266 ! DNA ligation + +[Term] +id: GO:0051108 +name: carnitine-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA." [MetaCyc:DCARNCOALIG-RXN] +synonym: "carnitine synthetase activity" EXACT [] +synonym: "crotonobetaine/carnitine-CoA ligase activity" BROAD [] +xref: MetaCyc:DCARNCOALIG-RXN +xref: RHEA:30543 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0051109 +name: crotonobetaine-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA." [MetaCyc:CROTCOALIG-RXN] +synonym: "crotonobetaine-CoA synthase activity" EXACT [] +synonym: "crotonobetaine/carnitine-CoA ligase activity" BROAD [] +xref: MetaCyc:CROTCOALIG-RXN +xref: RHEA:30079 +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0051110 +name: peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine +namespace: biological_process +def: "The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine)." [RESID:AA0372] +xref: RESID:AA0372 +is_a: GO:0051114 ! peptidyl-histidine uridylylation + +[Term] +id: GO:0051111 +name: peptidyl-histidine adenylylation +namespace: biological_process +def: "The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine)." [RESID:AA0371] +xref: RESID:AA0371 +is_a: GO:0018117 ! protein adenylylation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0051112 +name: peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine +namespace: biological_process +def: "The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine)." [RESID:AA0371] +xref: RESID:AA0371 +is_a: GO:0051111 ! peptidyl-histidine adenylylation + +[Term] +id: GO:0051113 +name: enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine +namespace: biological_process +def: "The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine)." [RESID:AA0371] +xref: RESID:AA0371 +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0051112 ! peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine + +[Term] +id: GO:0051114 +name: peptidyl-histidine uridylylation +namespace: biological_process +def: "The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine)." [RESID:AA0372] +xref: RESID:AA0372 +is_a: GO:0018177 ! protein uridylylation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0051115 +name: enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine +namespace: biological_process +def: "The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine)." [RESID:AA0372] +xref: RESID:AA0372 +is_a: GO:0018307 ! enzyme active site formation +is_a: GO:0051110 ! peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine + +[Term] +id: GO:0051116 +name: cobaltochelatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate." [EC:6.6.1.2, RHEA:15341] +synonym: "CobN-CobST" RELATED [EC:6.6.1.2] +synonym: "CobNST" NARROW [] +synonym: "hydrogenobyrinic acid a,c-diamide cobaltochelatase activity" EXACT [] +synonym: "hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)" EXACT [EC:6.6.1.2] +xref: EC:6.6.1.2 +xref: KEGG_REACTION:R05227 +xref: MetaCyc:R342-RXN +xref: RHEA:15341 +is_a: GO:0051003 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes + +[Term] +id: GO:0051117 +name: ATPase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP." [GOC:ai] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0051118 +name: glucan endo-1,3-alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran." [EC:3.2.1.59] +synonym: "1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.59] +synonym: "cariogenanase activity" EXACT [EC:3.2.1.59] +synonym: "cariogenase activity" EXACT [EC:3.2.1.59] +synonym: "endo-(1->3)-alpha-glucanase activity" EXACT [EC:3.2.1.59] +synonym: "endo-1,3-alpha-D-glucanase activity" EXACT [EC:3.2.1.59] +synonym: "endo-1,3-alpha-glucanase activity" EXACT [EC:3.2.1.59] +synonym: "mutanase activity" EXACT [EC:3.2.1.59] +xref: EC:3.2.1.59 +xref: MetaCyc:3.2.1.59-RXN +is_a: GO:0015926 ! glucosidase activity + +[Term] +id: GO:0051119 +name: sugar transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +synonym: "sugar/polyol channel activity" NARROW [] +xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" +xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity + +[Term] +id: GO:0051120 +name: hepoxilin A3 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3." [PMID:15123652] +xref: Reactome:R-HSA-2161794 "Arachidonic acid is converted to HXA3/B3 by ALOX12" +xref: Reactome:R-HSA-8942208 "ALOXE3 isomerises 12R-HpETE to HXA3" +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0051121 +name: hepoxilin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology." [PMID:15123652] +synonym: "hepoxilin metabolism" EXACT [] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process + +[Term] +id: GO:0051122 +name: hepoxilin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology." [GOC:ai] +synonym: "hepoxilin anabolism" EXACT [] +synonym: "hepoxilin biosynthesis" EXACT [] +synonym: "hepoxilin formation" EXACT [] +synonym: "hepoxilin synthesis" EXACT [] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:0051121 ! hepoxilin metabolic process + +[Term] +id: GO:0051123 +name: RNA polymerase II preinitiation complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase." [GOC:txnOH, PMID:10882737, PMID:15020047] +synonym: "RNA polymerase II transcription PIC biosynthesis" EXACT [] +synonym: "RNA polymerase II transcription PIC formation" EXACT [] +synonym: "RNA polymerase II transcriptional preinitiation complex assembly" EXACT [] +synonym: "RNA polymerase II transcriptional preinitiation complex formation" EXACT [] +is_a: GO:0070897 ! transcription preinitiation complex assembly +relationship: part_of GO:0006367 ! transcription initiation from RNA polymerase II promoter + +[Term] +id: GO:0051124 +name: synaptic growth at neuromuscular junction +namespace: biological_process +def: "The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates." [ISBN:0721662544] +synonym: "cholinergic synaptogenesis" RELATED [] +is_a: GO:0007416 ! synapse assembly +is_a: GO:0007528 ! neuromuscular junction development +is_a: GO:0048589 ! developmental growth + +[Term] +id: GO:0051125 +name: regulation of actin nucleation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] +is_a: GO:0030833 ! regulation of actin filament polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045010 ! actin nucleation +relationship: regulates GO:0045010 ! actin nucleation + +[Term] +id: GO:0051126 +name: negative regulation of actin nucleation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] +synonym: "down regulation of actin nucleation" EXACT [] +synonym: "down-regulation of actin nucleation" EXACT [] +synonym: "downregulation of actin nucleation" EXACT [] +synonym: "inhibition of actin nucleation" NARROW [] +is_a: GO:0051125 ! regulation of actin nucleation +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045010 ! actin nucleation +relationship: negatively_regulates GO:0045010 ! actin nucleation + +[Term] +id: GO:0051127 +name: positive regulation of actin nucleation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] +synonym: "activation of actin nucleation" NARROW [] +synonym: "stimulation of actin nucleation" NARROW [] +synonym: "up regulation of actin nucleation" EXACT [] +synonym: "up-regulation of actin nucleation" EXACT [] +synonym: "upregulation of actin nucleation" EXACT [] +is_a: GO:0030838 ! positive regulation of actin filament polymerization +is_a: GO:0051125 ! regulation of actin nucleation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045010 ! actin nucleation +relationship: positively_regulates GO:0045010 ! actin nucleation + +[Term] +id: GO:0051128 +name: regulation of cellular component organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] +synonym: "regulation of cell organisation" RELATED [GOC:mah] +synonym: "regulation of cell organization" RELATED [GOC:mah] +synonym: "regulation of cellular component organisation" EXACT [] +synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016043 ! cellular component organization +relationship: regulates GO:0016043 ! cellular component organization + +[Term] +id: GO:0051129 +name: negative regulation of cellular component organization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] +synonym: "down regulation of cell organization" EXACT [] +synonym: "down-regulation of cell organization" EXACT [] +synonym: "downregulation of cell organization" EXACT [] +synonym: "inhibition of cell organization" NARROW [] +synonym: "negative regulation of cell organisation" RELATED [GOC:mah] +synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016043 ! cellular component organization +relationship: negatively_regulates GO:0016043 ! cellular component organization + +[Term] +id: GO:0051130 +name: positive regulation of cellular component organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] +synonym: "activation of cell organization" NARROW [] +synonym: "positive regulation of cell organisation" EXACT [] +synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah] +synonym: "stimulation of cell organization" NARROW [] +synonym: "up regulation of cell organization" EXACT [] +synonym: "up-regulation of cell organization" EXACT [] +synonym: "upregulation of cell organization" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016043 ! cellular component organization +relationship: positively_regulates GO:0016043 ! cellular component organization + +[Term] +id: GO:0051131 +name: chaperone-mediated protein complex assembly +namespace: biological_process +alt_id: GO:0034619 +def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex." [GOC:ai] +synonym: "cellular chaperone-mediated protein complex assembly" EXACT [] +synonym: "chaperone activity" RELATED [] +synonym: "protein complex assembly, multichaperone pathway" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0051132 +name: NK T cell activation +namespace: biological_process +def: "The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [ISBN:0781735149, PMID:12154375, PMID:9133426] +comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repetoire of variable region gene segments. +synonym: "natural killer T cell activation" EXACT [] +synonym: "natural T cell activation" EXACT [] +synonym: "NK T lymphocyte activation" EXACT [] +synonym: "NK T-cell activation" EXACT [] +synonym: "NK T-lymphocyte activation" EXACT [] +synonym: "NKT cell activation" EXACT [] +synonym: "NT cell activation" EXACT [] +is_a: GO:0046631 ! alpha-beta T cell activation + +[Term] +id: GO:0051133 +name: regulation of NK T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "regulation of natural killer T cell activation" EXACT [] +synonym: "regulation of natural T cell activation" EXACT [] +synonym: "regulation of NK T lymphocyte activation" EXACT [] +synonym: "regulation of NK T-cell activation" EXACT [] +synonym: "regulation of NK T-lymphocyte activation" EXACT [] +synonym: "regulation of NKT cell activation" EXACT [] +synonym: "regulation of NT cell activation" EXACT [] +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051132 ! NK T cell activation +relationship: regulates GO:0051132 ! NK T cell activation + +[Term] +id: GO:0051134 +name: negative regulation of NK T cell activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "down regulation of NK T cell activation" EXACT [] +synonym: "down-regulation of NK T cell activation" EXACT [] +synonym: "downregulation of NK T cell activation" EXACT [] +synonym: "inhibition of NK T cell activation" NARROW [] +synonym: "negative regulation of natural killer T cell activation" EXACT [] +synonym: "negative regulation of natural T cell activation" EXACT [] +synonym: "negative regulation of NK T lymphocyte activation" EXACT [] +synonym: "negative regulation of NK T-cell activation" EXACT [] +synonym: "negative regulation of NK T-lymphocyte activation" EXACT [] +synonym: "negative regulation of NKT cell activation" EXACT [] +synonym: "negative regulation of NT cell activation" EXACT [] +is_a: GO:0046636 ! negative regulation of alpha-beta T cell activation +is_a: GO:0051133 ! regulation of NK T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051132 ! NK T cell activation +relationship: negatively_regulates GO:0051132 ! NK T cell activation + +[Term] +id: GO:0051135 +name: positive regulation of NK T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "activation of NK T cell activation" NARROW [] +synonym: "positive regulation of natural killer T cell activation" EXACT [] +synonym: "positive regulation of natural T cell activation" EXACT [] +synonym: "positive regulation of NK T lymphocyte activation" EXACT [] +synonym: "positive regulation of NK T-cell activation" EXACT [] +synonym: "positive regulation of NK T-lymphocyte activation" EXACT [] +synonym: "positive regulation of NKT cell activation" EXACT [] +synonym: "positive regulation of NT cell activation" EXACT [] +synonym: "stimulation of NK T cell activation" NARROW [] +synonym: "up regulation of NK T cell activation" EXACT [] +synonym: "up-regulation of NK T cell activation" EXACT [] +synonym: "upregulation of NK T cell activation" EXACT [] +is_a: GO:0046635 ! positive regulation of alpha-beta T cell activation +is_a: GO:0051133 ! regulation of NK T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051132 ! NK T cell activation +relationship: positively_regulates GO:0051132 ! NK T cell activation + +[Term] +id: GO:0051136 +name: regulation of NK T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "regulation of natural killer T cell differentiation" EXACT [] +synonym: "regulation of natural T cell differentiation" EXACT [] +synonym: "regulation of NK T cell development" RELATED [GOC:add] +synonym: "regulation of NK T lymphocyte differentiation" EXACT [] +synonym: "regulation of NK T-cell differentiation" EXACT [] +synonym: "regulation of NK T-lymphocyte differentiation" EXACT [] +synonym: "regulation of NKT cell differentiation" EXACT [] +synonym: "regulation of NT cell differentiation" EXACT [] +is_a: GO:0046637 ! regulation of alpha-beta T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001865 ! NK T cell differentiation +relationship: regulates GO:0001865 ! NK T cell differentiation + +[Term] +id: GO:0051137 +name: negative regulation of NK T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "down regulation of NK T cell differentiation" EXACT [] +synonym: "down-regulation of NK T cell differentiation" EXACT [] +synonym: "downregulation of NK T cell differentiation" EXACT [] +synonym: "inhibition of NK T cell differentiation" NARROW [] +synonym: "negative regulation of natural killer T cell differentiation" EXACT [] +synonym: "negative regulation of natural T cell differentiation" EXACT [] +synonym: "negative regulation of NK T cell development" RELATED [GOC:add] +synonym: "negative regulation of NK T lymphocyte differentiation" EXACT [] +synonym: "negative regulation of NK T-cell differentiation" EXACT [] +synonym: "negative regulation of NK T-lymphocyte differentiation" EXACT [] +synonym: "negative regulation of NKT cell differentiation" EXACT [] +synonym: "negative regulation of NT cell differentiation" EXACT [] +is_a: GO:0046639 ! negative regulation of alpha-beta T cell differentiation +is_a: GO:0051136 ! regulation of NK T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001865 ! NK T cell differentiation +relationship: negatively_regulates GO:0001865 ! NK T cell differentiation + +[Term] +id: GO:0051138 +name: positive regulation of NK T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "activation of NK T cell differentiation" NARROW [] +synonym: "positive regulation of natural killer T cell differentiation" EXACT [] +synonym: "positive regulation of natural T cell differentiation" EXACT [] +synonym: "positive regulation of NK T cell development" RELATED [GOC:add] +synonym: "positive regulation of NK T lymphocyte differentiation" EXACT [] +synonym: "positive regulation of NK T-cell differentiation" EXACT [] +synonym: "positive regulation of NK T-lymphocyte differentiation" EXACT [] +synonym: "positive regulation of NKT cell differentiation" EXACT [] +synonym: "positive regulation of NT cell differentiation" EXACT [] +synonym: "stimulation of NK T cell differentiation" NARROW [] +synonym: "up regulation of NK T cell differentiation" EXACT [] +synonym: "up-regulation of NK T cell differentiation" EXACT [] +synonym: "upregulation of NK T cell differentiation" EXACT [] +is_a: GO:0046638 ! positive regulation of alpha-beta T cell differentiation +is_a: GO:0051136 ! regulation of NK T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001865 ! NK T cell differentiation +relationship: positively_regulates GO:0001865 ! NK T cell differentiation + +[Term] +id: GO:0051139 +name: metal ion:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in)." [GOC:mlg] +synonym: "metal ion:hydrogen antiporter activity" EXACT [] +xref: Reactome:R-HSA-435171 "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages" +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:0046873 ! metal ion transmembrane transporter activity + +[Term] +id: GO:0051140 +name: regulation of NK T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "regulation of natural killer T cell proliferation" EXACT [] +synonym: "regulation of natural T cell proliferation" EXACT [] +synonym: "regulation of NK T lymphocyte proliferation" EXACT [] +synonym: "regulation of NK T-cell proliferation" EXACT [] +synonym: "regulation of NK T-lymphocyte proliferation" EXACT [] +synonym: "regulation of NKT cell proliferation" EXACT [] +synonym: "regulation of NT cell proliferation" EXACT [] +is_a: GO:0046640 ! regulation of alpha-beta T cell proliferation +is_a: GO:0051133 ! regulation of NK T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001866 ! NK T cell proliferation +relationship: regulates GO:0001866 ! NK T cell proliferation + +[Term] +id: GO:0051141 +name: negative regulation of NK T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "down regulation of NK T cell proliferation" EXACT [] +synonym: "down-regulation of NK T cell proliferation" EXACT [] +synonym: "downregulation of NK T cell proliferation" EXACT [] +synonym: "inhibition of NK T cell proliferation" NARROW [] +synonym: "negative regulation of natural killer T cell proliferation" EXACT [] +synonym: "negative regulation of natural T cell proliferation" EXACT [] +synonym: "negative regulation of NK T lymphocyte proliferation" EXACT [] +synonym: "negative regulation of NK T-cell proliferation" EXACT [] +synonym: "negative regulation of NK T-lymphocyte proliferation" EXACT [] +synonym: "negative regulation of NKT cell proliferation" EXACT [] +synonym: "negative regulation of NT cell proliferation" EXACT [] +is_a: GO:0046642 ! negative regulation of alpha-beta T cell proliferation +is_a: GO:0051134 ! negative regulation of NK T cell activation +is_a: GO:0051140 ! regulation of NK T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001866 ! NK T cell proliferation +relationship: negatively_regulates GO:0001866 ! NK T cell proliferation + +[Term] +id: GO:0051142 +name: positive regulation of NK T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149, PMID:12154375, PMID:9133426] +synonym: "activation of NK T cell proliferation" NARROW [] +synonym: "positive regulation of natural killer T cell proliferation" EXACT [] +synonym: "positive regulation of natural T cell proliferation" EXACT [] +synonym: "positive regulation of NK T lymphocyte proliferation" EXACT [] +synonym: "positive regulation of NK T-cell proliferation" EXACT [] +synonym: "positive regulation of NK T-lymphocyte proliferation" EXACT [] +synonym: "positive regulation of NKT cell proliferation" EXACT [] +synonym: "positive regulation of NT cell proliferation" EXACT [] +synonym: "stimulation of NK T cell proliferation" NARROW [] +synonym: "up regulation of NK T cell proliferation" EXACT [] +synonym: "up-regulation of NK T cell proliferation" EXACT [] +synonym: "upregulation of NK T cell proliferation" EXACT [] +is_a: GO:0046641 ! positive regulation of alpha-beta T cell proliferation +is_a: GO:0051135 ! positive regulation of NK T cell activation +is_a: GO:0051140 ! regulation of NK T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001866 ! NK T cell proliferation +relationship: positively_regulates GO:0001866 ! NK T cell proliferation + +[Term] +id: GO:0051143 +name: propanediol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items." [PMID:15995211] +synonym: "1,2-dihydroxypropane metabolic process" EXACT [] +synonym: "1,2-dihydroxypropane metabolism" EXACT [] +synonym: "propanediol metabolism" EXACT [] +synonym: "propylene glycol metabolic process" EXACT [] +synonym: "propylene glycol metabolism" EXACT [] +is_a: GO:0042844 ! glycol metabolic process + +[Term] +id: GO:0051144 +name: propanediol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH." [GOC:ai] +synonym: "1,2-dihydroxypropane catabolic process" EXACT [] +synonym: "1,2-dihydroxypropane catabolism" EXACT [] +synonym: "propanediol breakdown" EXACT [] +synonym: "propanediol catabolism" EXACT [] +synonym: "propanediol degradation" EXACT [] +synonym: "propylene glycol catabolic process" EXACT [] +synonym: "propylene glycol catabolism" EXACT [] +is_a: GO:0042846 ! glycol catabolic process +is_a: GO:0051143 ! propanediol metabolic process + +[Term] +id: GO:0051145 +name: smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai] +synonym: "nonstriated muscle cell differentiation" EXACT [] +is_a: GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0051146 +name: striated muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai] +synonym: "voluntary muscle cell differentiation" NARROW [] +is_a: GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0051147 +name: regulation of muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042692 ! muscle cell differentiation +relationship: regulates GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0051148 +name: negative regulation of muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] +synonym: "down regulation of muscle cell differentiation" EXACT [] +synonym: "down-regulation of muscle cell differentiation" EXACT [] +synonym: "downregulation of muscle cell differentiation" EXACT [] +synonym: "inhibition of muscle cell differentiation" NARROW [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0051147 ! regulation of muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042692 ! muscle cell differentiation +relationship: negatively_regulates GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0051149 +name: positive regulation of muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] +synonym: "activation of muscle cell differentiation" NARROW [] +synonym: "stimulation of muscle cell differentiation" NARROW [] +synonym: "up regulation of muscle cell differentiation" EXACT [] +synonym: "up-regulation of muscle cell differentiation" EXACT [] +synonym: "upregulation of muscle cell differentiation" EXACT [] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0051147 ! regulation of muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042692 ! muscle cell differentiation +relationship: positively_regulates GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0051150 +name: regulation of smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] +is_a: GO:0051147 ! regulation of muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051145 ! smooth muscle cell differentiation +relationship: regulates GO:0051145 ! smooth muscle cell differentiation + +[Term] +id: GO:0051151 +name: negative regulation of smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] +synonym: "down regulation of smooth muscle cell differentiation" EXACT [] +synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] +synonym: "downregulation of smooth muscle cell differentiation" EXACT [] +synonym: "inhibition of smooth muscle cell differentiation" NARROW [] +is_a: GO:0051148 ! negative regulation of muscle cell differentiation +is_a: GO:0051150 ! regulation of smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051145 ! smooth muscle cell differentiation +relationship: negatively_regulates GO:0051145 ! smooth muscle cell differentiation + +[Term] +id: GO:0051152 +name: positive regulation of smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] +synonym: "activation of smooth muscle cell differentiation" NARROW [] +synonym: "stimulation of smooth muscle cell differentiation" NARROW [] +synonym: "up regulation of smooth muscle cell differentiation" EXACT [] +synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] +synonym: "upregulation of smooth muscle cell differentiation" EXACT [] +is_a: GO:0051149 ! positive regulation of muscle cell differentiation +is_a: GO:0051150 ! regulation of smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051145 ! smooth muscle cell differentiation +relationship: positively_regulates GO:0051145 ! smooth muscle cell differentiation + +[Term] +id: GO:0051153 +name: regulation of striated muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] +is_a: GO:0051147 ! regulation of muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051146 ! striated muscle cell differentiation +relationship: regulates GO:0051146 ! striated muscle cell differentiation + +[Term] +id: GO:0051154 +name: negative regulation of striated muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] +synonym: "down regulation of striated muscle cell differentiation" EXACT [] +synonym: "down-regulation of striated muscle cell differentiation" EXACT [] +synonym: "downregulation of striated muscle cell differentiation" EXACT [] +synonym: "inhibition of striated muscle cell differentiation" NARROW [] +is_a: GO:0051148 ! negative regulation of muscle cell differentiation +is_a: GO:0051153 ! regulation of striated muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051146 ! striated muscle cell differentiation +relationship: negatively_regulates GO:0051146 ! striated muscle cell differentiation + +[Term] +id: GO:0051155 +name: positive regulation of striated muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] +synonym: "activation of striated muscle cell differentiation" NARROW [] +synonym: "stimulation of striated muscle cell differentiation" NARROW [] +synonym: "up regulation of striated muscle cell differentiation" EXACT [] +synonym: "up-regulation of striated muscle cell differentiation" EXACT [] +synonym: "upregulation of striated muscle cell differentiation" EXACT [] +is_a: GO:0051149 ! positive regulation of muscle cell differentiation +is_a: GO:0051153 ! regulation of striated muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051146 ! striated muscle cell differentiation +relationship: positively_regulates GO:0051146 ! striated muscle cell differentiation + +[Term] +id: GO:0051156 +name: glucose 6-phosphate metabolic process +namespace: biological_process +alt_id: GO:0006010 +def: "The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6." [GOC:ai] +synonym: "glucose 6-phosphate metabolism" EXACT [] +synonym: "glucose 6-phosphate utilization" RELATED [GOC:mah] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0051157 +name: arabitol catabolic process +namespace: biological_process +alt_id: GO:0019591 +def: "The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "arabitol breakdown" EXACT [] +synonym: "arabitol catabolism" EXACT [] +synonym: "arabitol degradation" EXACT [] +synonym: "arabitol utilization" RELATED [GOC:mah] +is_a: GO:0019527 ! pentitol catabolic process +is_a: GO:0051161 ! arabitol metabolic process + +[Term] +id: GO:0051158 +name: L-arabitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "L-arabitol breakdown" EXACT [] +synonym: "L-arabitol catabolism" EXACT [] +synonym: "L-arabitol degradation" EXACT [] +is_a: GO:0051157 ! arabitol catabolic process +is_a: GO:0051162 ! L-arabitol metabolic process + +[Term] +id: GO:0051159 +name: D-arabitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms." [ISBN:0198506732] +synonym: "D-arabitol breakdown" EXACT [] +synonym: "D-arabitol catabolism" EXACT [] +synonym: "D-arabitol degradation" EXACT [] +is_a: GO:0051157 ! arabitol catabolic process +is_a: GO:0051163 ! D-arabitol metabolic process + +[Term] +id: GO:0051160 +name: L-xylitol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group." [GOC:ai] +synonym: "L-xylitol breakdown" EXACT [] +synonym: "L-xylitol catabolism" EXACT [] +synonym: "L-xylitol degradation" EXACT [] +is_a: GO:0019527 ! pentitol catabolic process +is_a: GO:0051164 ! L-xylitol metabolic process + +[Term] +id: GO:0051161 +name: arabitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "arabitol metabolism" EXACT [] +is_a: GO:0019519 ! pentitol metabolic process + +[Term] +id: GO:0051162 +name: L-arabitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group." [ISBN:0198506732] +synonym: "L-arabitol metabolism" EXACT [] +is_a: GO:0051161 ! arabitol metabolic process + +[Term] +id: GO:0051163 +name: D-arabitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms." [ISBN:0198506732] +synonym: "D-arabitol metabolism" EXACT [] +is_a: GO:0051161 ! arabitol metabolic process + +[Term] +id: GO:0051164 +name: L-xylitol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets." [GOC:ai] +synonym: "L-xylitol metabolism" EXACT [] +is_a: GO:0019519 ! pentitol metabolic process + +[Term] +id: GO:0051165 +name: 2,5-dihydroxypyridine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2,5-dihydroxypyridine." [GOC:ai] +synonym: "2,5-dihydroxypyridine metabolism" EXACT [] +synonym: "pyridine-2,5-diol metabolic process" EXACT [CHEBI:16364] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0051166 +name: 2,5-dihydroxypyridine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine." [GOC:ai] +synonym: "2,5-dihydroxypyridine breakdown" EXACT [] +synonym: "2,5-dihydroxypyridine catabolism" EXACT [] +synonym: "2,5-dihydroxypyridine degradation" EXACT [] +synonym: "pyridine-2,5-diol catabolic process" EXACT [CHEBI:16364] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0051165 ! 2,5-dihydroxypyridine metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process + +[Term] +id: GO:0051167 +name: xylulose 5-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway." [ISBN:0721662544] +synonym: "D-xylulose 5-phosphate metabolic process" EXACT [] +synonym: "D-xylulose 5-phosphate metabolism" EXACT [] +synonym: "D-xylulose-5-phosphate metabolic process" EXACT [] +synonym: "D-xylulose-5-phosphate metabolism" EXACT [] +synonym: "xylulose 5-phosphate metabolism" EXACT [] +synonym: "xylulose-5-phosphate metabolic process" EXACT [] +synonym: "xylulose-5-phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0051168 +name: nuclear export +namespace: biological_process +def: "The directed movement of substances out of the nucleus." [GOC:ai] +synonym: "export from nucleus" EXACT [] +synonym: "nucleus export" EXACT [] +synonym: "substance nuclear export" EXACT [] +is_a: GO:0006913 ! nucleocytoplasmic transport + +[Term] +id: GO:0051169 +name: nuclear transport +namespace: biological_process +def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai] +subset: goslim_yeast +synonym: "nucleus transport" EXACT [] +xref: Wikipedia:Nuclear_transport +is_a: GO:0046907 ! intracellular transport + +[Term] +id: GO:0051170 +name: import into nucleus +namespace: biological_process +alt_id: GO:1902593 +def: "The directed movement of substances into the nucleus." [GOC:ai] +synonym: "nuclear import" EXACT [] +synonym: "single organism nuclear import" EXACT [GOC:TermGenie] +synonym: "single-organism nuclear import" RELATED [] +synonym: "substance nuclear import" EXACT [] +is_a: GO:0006913 ! nucleocytoplasmic transport +created_by: jl +creation_date: 2013-12-19T15:26:34Z + +[Term] +id: GO:0051171 +name: regulation of nitrogen compound metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] +synonym: "regulation of nitrogen metabolic process" EXACT [GOC:tb] +synonym: "regulation of nitrogen metabolism" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006807 ! nitrogen compound metabolic process +relationship: regulates GO:0006807 ! nitrogen compound metabolic process + +[Term] +id: GO:0051172 +name: negative regulation of nitrogen compound metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] +synonym: "down regulation of nitrogen metabolic process" EXACT [] +synonym: "down-regulation of nitrogen metabolic process" EXACT [] +synonym: "downregulation of nitrogen metabolic process" EXACT [] +synonym: "inhibition of nitrogen metabolic process" NARROW [] +synonym: "negative regulation of nitrogen metabolic process" EXACT [GOC:tb] +synonym: "negative regulation of nitrogen metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006807 ! nitrogen compound metabolic process +relationship: negatively_regulates GO:0006807 ! nitrogen compound metabolic process + +[Term] +id: GO:0051173 +name: positive regulation of nitrogen compound metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] +synonym: "activation of nitrogen metabolic process" NARROW [] +synonym: "positive regulation of nitrogen metabolic process" EXACT [GOC:tb] +synonym: "positive regulation of nitrogen metabolism" EXACT [] +synonym: "stimulation of nitrogen metabolic process" NARROW [] +synonym: "up regulation of nitrogen metabolic process" EXACT [] +synonym: "up-regulation of nitrogen metabolic process" EXACT [] +synonym: "upregulation of nitrogen metabolic process" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006807 ! nitrogen compound metabolic process +relationship: positively_regulates GO:0006807 ! nitrogen compound metabolic process + +[Term] +id: GO:0051174 +name: regulation of phosphorus metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] +synonym: "regulation of phosphorus metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006793 ! phosphorus metabolic process +relationship: regulates GO:0006793 ! phosphorus metabolic process + +[Term] +id: GO:0051175 +name: negative regulation of sulfur metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] +synonym: "down regulation of sulfur metabolic process" EXACT [] +synonym: "down-regulation of sulfur metabolic process" EXACT [] +synonym: "downregulation of sulfur metabolic process" EXACT [] +synonym: "inhibition of sulfur metabolic process" NARROW [] +synonym: "negative regulation of sulfur metabolism" EXACT [] +synonym: "negative regulation of sulphur metabolic process" EXACT [] +synonym: "negative regulation of sulphur metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006790 ! sulfur compound metabolic process +relationship: negatively_regulates GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0051176 +name: positive regulation of sulfur metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] +synonym: "activation of sulfur metabolic process" NARROW [] +synonym: "positive regulation of sulfur metabolism" EXACT [] +synonym: "positive regulation of sulphur metabolic process" EXACT [] +synonym: "positive regulation of sulphur metabolism" EXACT [] +synonym: "stimulation of sulfur metabolic process" NARROW [] +synonym: "up regulation of sulfur metabolic process" EXACT [] +synonym: "up-regulation of sulfur metabolic process" EXACT [] +synonym: "upregulation of sulfur metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006790 ! sulfur compound metabolic process +relationship: positively_regulates GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0051177 +name: meiotic sister chromatid cohesion +namespace: biological_process +def: "The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis." [GOC:ai] +is_a: GO:0007062 ! sister chromatid cohesion +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +relationship: part_of GO:0045144 ! meiotic sister chromatid segregation + +[Term] +id: GO:0051178 +name: meiotic chromosome decondensation +namespace: biological_process +def: "The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells." [GOC:ai] +is_a: GO:0051312 ! chromosome decondensation +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +intersection_of: GO:0051312 ! chromosome decondensation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0051179 +name: localization +namespace: biological_process +alt_id: GO:1902578 +def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos] +subset: goslim_pir +synonym: "establishment and maintenance of cellular component location" NARROW [] +synonym: "establishment and maintenance of localization" EXACT [] +synonym: "establishment and maintenance of position" EXACT [] +synonym: "establishment and maintenance of substance location" NARROW [] +synonym: "establishment and maintenance of substrate location" NARROW [] +synonym: "localisation" EXACT [GOC:mah] +synonym: "single organism localization" RELATED [GOC:TermGenie] +synonym: "single-organism localization" RELATED [] +is_a: GO:0008150 ! biological_process +created_by: jl +creation_date: 2013-12-18T13:51:04Z + +[Term] +id: GO:0051180 +name: vitamin transport +namespace: biological_process +def: "The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] +subset: goslim_pir +synonym: "vitamin or cofactor transport" BROAD [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0051181 +name: cofactor transport +namespace: biological_process +def: "The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein." [GOC:ai] +subset: goslim_pir +synonym: "vitamin or cofactor transport" BROAD [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0051182 +name: coenzyme transport +namespace: biological_process +def: "The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai] +is_a: GO:0051181 ! cofactor transport + +[Term] +id: GO:0051184 +name: cofactor transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein." [GOC:ai] +synonym: "cofactor transporter activity" RELATED [] +synonym: "vitamin or cofactor transporter activity" BROAD [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0051181 ! cofactor transport + +[Term] +id: GO:0051185 +name: coenzyme transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai] +synonym: "coenzyme transporter activity" RELATED [] +is_a: GO:0051184 ! cofactor transmembrane transporter activity +relationship: part_of GO:0051182 ! coenzyme transport + +[Term] +id: GO:0051186 +name: cofactor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate." [GOC:ai] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +synonym: "cofactor metabolism" EXACT [] +is_a: GO:0044237 ! cellular metabolic process + +[Term] +id: GO:0051187 +name: cofactor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein." [GOC:ai] +synonym: "cofactor breakdown" EXACT [] +synonym: "cofactor catabolism" EXACT [] +synonym: "cofactor degradation" EXACT [] +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051188 +name: cofactor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein." [GOC:ai] +synonym: "cofactor anabolism" EXACT [] +synonym: "cofactor biosynthesis" EXACT [] +synonym: "cofactor formation" EXACT [] +synonym: "cofactor synthesis" EXACT [] +is_a: GO:0044249 ! cellular biosynthetic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051189 +name: prosthetic group metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein." [GOC:ai] +subset: goslim_pir +synonym: "coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "coenzyme and prosthetic group metabolism" BROAD [] +synonym: "prosthetic group metabolism" EXACT [] +is_a: GO:0051186 ! cofactor metabolic process +relationship: part_of GO:0044267 ! cellular protein metabolic process + +[Term] +id: GO:0051190 +name: prosthetic group catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein." [GOC:ai] +synonym: "coenzyme and prosthetic group catabolic process" BROAD [] +synonym: "coenzyme and prosthetic group catabolism" BROAD [] +synonym: "prosthetic group breakdown" EXACT [] +synonym: "prosthetic group catabolism" EXACT [] +synonym: "prosthetic group degradation" EXACT [] +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:0051189 ! prosthetic group metabolic process +relationship: part_of GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0051191 +name: prosthetic group biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein." [GOC:ai] +synonym: "coenzyme and prosthetic group biosynthesis" BROAD [] +synonym: "coenzyme and prosthetic group biosynthetic process" BROAD [] +synonym: "prosthetic group anabolism" EXACT [] +synonym: "prosthetic group biosynthesis" EXACT [] +synonym: "prosthetic group formation" EXACT [] +synonym: "prosthetic group synthesis" EXACT [] +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0051189 ! prosthetic group metabolic process +relationship: part_of GO:0009059 ! macromolecule biosynthetic process + +[Term] +id: GO:0051192 +name: prosthetic group binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein." [GOC:ai, GOC:vw] +is_a: GO:0048037 ! cofactor binding + +[Term] +id: GO:0051193 +name: regulation of cofactor metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] +synonym: "regulation of cofactor metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051186 ! cofactor metabolic process +relationship: regulates GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051194 +name: positive regulation of cofactor metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] +synonym: "activation of cofactor metabolic process" NARROW [] +synonym: "positive regulation of cofactor metabolism" EXACT [] +synonym: "stimulation of cofactor metabolic process" NARROW [] +synonym: "up regulation of cofactor metabolic process" EXACT [] +synonym: "up-regulation of cofactor metabolic process" EXACT [] +synonym: "upregulation of cofactor metabolic process" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051186 ! cofactor metabolic process +relationship: positively_regulates GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051195 +name: negative regulation of cofactor metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] +synonym: "down regulation of cofactor metabolic process" EXACT [] +synonym: "down-regulation of cofactor metabolic process" EXACT [] +synonym: "downregulation of cofactor metabolic process" EXACT [] +synonym: "inhibition of cofactor metabolic process" NARROW [] +synonym: "negative regulation of cofactor metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051186 ! cofactor metabolic process +relationship: negatively_regulates GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051196 +name: regulation of coenzyme metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] +synonym: "regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "regulation of coenzyme metabolism" EXACT [] +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006732 ! coenzyme metabolic process +relationship: regulates GO:0006732 ! coenzyme metabolic process + +[Term] +id: GO:0051197 +name: positive regulation of coenzyme metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] +synonym: "activation of coenzyme metabolic process" NARROW [] +synonym: "positive regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "positive regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "positive regulation of coenzyme metabolism" EXACT [] +synonym: "stimulation of coenzyme metabolic process" NARROW [] +synonym: "up regulation of coenzyme metabolic process" EXACT [] +synonym: "up-regulation of coenzyme metabolic process" EXACT [] +synonym: "upregulation of coenzyme metabolic process" EXACT [] +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006732 ! coenzyme metabolic process +relationship: positively_regulates GO:0006732 ! coenzyme metabolic process + +[Term] +id: GO:0051198 +name: negative regulation of coenzyme metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] +synonym: "down regulation of coenzyme metabolic process" EXACT [] +synonym: "down-regulation of coenzyme metabolic process" EXACT [] +synonym: "downregulation of coenzyme metabolic process" EXACT [] +synonym: "inhibition of coenzyme metabolic process" NARROW [] +synonym: "negative regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "negative regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "negative regulation of coenzyme metabolism" EXACT [] +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006732 ! coenzyme metabolic process +relationship: negatively_regulates GO:0006732 ! coenzyme metabolic process + +[Term] +id: GO:0051199 +name: regulation of prosthetic group metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] +synonym: "regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "regulation of prosthetic group metabolism" EXACT [] +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051189 ! prosthetic group metabolic process +relationship: regulates GO:0051189 ! prosthetic group metabolic process + +[Term] +id: GO:0051200 +name: positive regulation of prosthetic group metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] +synonym: "activation of prosthetic group metabolic process" NARROW [] +synonym: "positive regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "positive regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "positive regulation of prosthetic group metabolism" EXACT [] +synonym: "stimulation of prosthetic group metabolic process" NARROW [] +synonym: "up regulation of prosthetic group metabolic process" EXACT [] +synonym: "up-regulation of prosthetic group metabolic process" EXACT [] +synonym: "upregulation of prosthetic group metabolic process" EXACT [] +is_a: GO:0032270 ! positive regulation of cellular protein metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:0051199 ! regulation of prosthetic group metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051189 ! prosthetic group metabolic process +relationship: positively_regulates GO:0051189 ! prosthetic group metabolic process + +[Term] +id: GO:0051201 +name: negative regulation of prosthetic group metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] +synonym: "down regulation of prosthetic group metabolic process" EXACT [] +synonym: "down-regulation of prosthetic group metabolic process" EXACT [] +synonym: "downregulation of prosthetic group metabolic process" EXACT [] +synonym: "inhibition of prosthetic group metabolic process" NARROW [] +synonym: "negative regulation of coenzyme and prosthetic group metabolic process" BROAD [] +synonym: "negative regulation of coenzyme and prosthetic group metabolism" BROAD [] +synonym: "negative regulation of prosthetic group metabolism" EXACT [] +is_a: GO:0032269 ! negative regulation of cellular protein metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:0051199 ! regulation of prosthetic group metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051189 ! prosthetic group metabolic process +relationship: negatively_regulates GO:0051189 ! prosthetic group metabolic process + +[Term] +id: GO:0051202 +name: phytochromobilin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity." [PMID:11500553] +synonym: "phytochromobilin metabolism" EXACT [] +is_a: GO:0033013 ! tetrapyrrole metabolic process +is_a: GO:0051186 ! cofactor metabolic process + +[Term] +id: GO:0051203 +name: peptidyl-aspartic acid reduction to form L-aspartyl aldehyde +namespace: biological_process +def: "The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein." [PMID:15237995, RESID:AA0373] +comment: See also UniProtKB:P04160. +synonym: "peptidyl-aspartic acid reduction to form L-aspartate-beta-semialdehyde" EXACT [] +synonym: "peptidyl-aspartic acid reduction to form L-beta-formylalanine" EXACT [] +xref: RESID:AA0373 +is_a: GO:0018197 ! peptidyl-aspartic acid modification + +[Term] +id: GO:0051204 +name: protein insertion into mitochondrial membrane +namespace: biological_process +def: "The process that results in the incorporation of a protein into a mitochondrial membrane." [GOC:ai] +synonym: "integral mitochondrial membrane protein localization" EXACT [] +synonym: "integral mitochondrial membrane protein positioning" EXACT [] +synonym: "localization of protein in mitochondrial membrane" EXACT [] +synonym: "positioning of protein in mitochondrial membrane" EXACT [] +synonym: "protein insertion into mitochondrion membrane" EXACT [] +synonym: "protein-mitochondrial membrane insertion" EXACT [] +synonym: "protein-mitochondrion membrane insertion" EXACT [] +is_a: GO:0006839 ! mitochondrial transport +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0051205 ! protein insertion into membrane +is_a: GO:0090151 ! establishment of protein localization to mitochondrial membrane +relationship: part_of GO:0070585 ! protein localization to mitochondrion +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15800 xsd:anyURI + +[Term] +id: GO:0051205 +name: protein insertion into membrane +namespace: biological_process +def: "The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers." [GOC:ai] +synonym: "integral membrane protein localization" EXACT [] +synonym: "integral membrane protein positioning" EXACT [] +synonym: "membrane protein localization" EXACT [] +synonym: "membrane protein positioning" EXACT [] +synonym: "protein-membrane insertion" EXACT [] +is_a: GO:0090150 ! establishment of protein localization to membrane +relationship: part_of GO:0034613 ! cellular protein localization +relationship: part_of GO:0061024 ! membrane organization + +[Term] +id: GO:0051206 +name: silicate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates." [GOC:ai] +synonym: "silicate metabolism" EXACT [] +is_a: GO:0043436 ! oxoacid metabolic process + +[Term] +id: GO:0051208 +name: sequestering of calcium ion +namespace: biological_process +def: "The process of binding or confining calcium ions such that they are separated from other components of a biological system." [GOC:ai] +synonym: "calcium ion (Ca2+) retention" EXACT [] +synonym: "calcium ion (Ca2+) sequestering" EXACT [] +synonym: "calcium ion (Ca2+) sequestration" EXACT [] +synonym: "calcium ion (Ca2+) storage" EXACT [] +synonym: "calcium ion storage activity" RELATED [] +synonym: "negative regulation of calcium ion (Ca2+) transport" RELATED [] +synonym: "retention of calcium ion (Ca2+)" EXACT [] +synonym: "sequestering of calcium ion (Ca2+)" EXACT [] +synonym: "sequestration of calcium ion (Ca2+)" EXACT [] +synonym: "storage of calcium ion (Ca2+)" EXACT [] +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0006874 ! cellular calcium ion homeostasis + +[Term] +id: GO:0051209 +name: release of sequestered calcium ion into cytosol +namespace: biological_process +def: "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment." [GOC:dph, GOC:hjd, GOC:mtg_lung, PMID:1814929] +synonym: "calcium ion (Ca2+) mobilization" BROAD [] +synonym: "calcium mobilization" BROAD [] +synonym: "cytoplasmic release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "cytoplasmic release of stored calcium ion (Ca2+)" BROAD [] +synonym: "cytosolic release of sequestered calcium ion (Ca2+)" EXACT [] +synonym: "cytosolic release of stored calcium ion (Ca2+)" EXACT [] +synonym: "release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "release of sequestered calcium ion into cytoplasm" BROAD [] +synonym: "release of stored calcium ion (Ca2+)" BROAD [] +synonym: "release of stored calcium ion (Ca2+) into cytoplasm" BROAD [] +synonym: "release of stored calcium ion (Ca2+) into cytosol" EXACT [] +is_a: GO:0051283 ! negative regulation of sequestering of calcium ion +is_a: GO:0097553 ! calcium ion transmembrane import into cytosol + +[Term] +id: GO:0051210 +name: isotropic cell growth +namespace: biological_process +def: "The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth." [GOC:ai, GOC:jid] +synonym: "uniform cell growth" RELATED [] +is_a: GO:0016049 ! cell growth + +[Term] +id: GO:0051211 +name: anisotropic cell growth +namespace: biological_process +def: "The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell." [GOC:ai] +synonym: "non-isotropic cell growth" EXACT [] +is_a: GO:0016049 ! cell growth + +[Term] +id: GO:0051212 +name: vanadium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with vanadium (V) ions." [GOC:ai] +is_a: GO:0046914 ! transition metal ion binding + +[Term] +id: GO:0051213 +name: dioxygenase activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products." [DOI:10.1016/S0040-4020(03)00944-X, GOC:bf] +subset: goslim_pir +xref: Reactome:R-HSA-112120 "Oxidative demethylation of 3-meC damaged DNA by ALKBH2" +xref: Reactome:R-HSA-112121 "Oxidative dealkylation of 1-etA damaged DNA By ALKBH2" +xref: Reactome:R-HSA-112124 "Oxidative demethylation of 3-meC damaged DNA By ALKBH3" +xref: Reactome:R-HSA-112125 "Oxidative dealkylation of 1-EtA damaged DNA by ABH3" +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0051214 +name: RNA virus induced gene silencing +namespace: biological_process +def: "Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing." [PMID:15165191] +synonym: "RNA VIGS" EXACT [] +synonym: "RNA virus-induced gene silencing" EXACT [] +is_a: GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0051215 +name: DNA virus induced gene silencing +namespace: biological_process +def: "Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing." [PMID:15165191] +synonym: "DNA VIGS" EXACT [] +synonym: "DNA virus-induced gene silencing" EXACT [] +is_a: GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0051216 +name: cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424] +synonym: "cartilage biogenesis" EXACT [] +synonym: "cartilage biosynthesis" EXACT [] +synonym: "cartilage element development" EXACT [] +synonym: "cartilage formation" EXACT [] +synonym: "cartilage organ development" EXACT [] +synonym: "chondrogenesis" EXACT [] +xref: Wikipedia:Chondrogenesis +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0001501 ! skeletal system development +relationship: part_of GO:0061448 ! connective tissue development + +[Term] +id: GO:0051217 +name: molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide) +namespace: biological_process +def: "The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)." [PDB:1Q16, PMID:12910261, RESID:AA0375] +xref: RESID:AA0375 +is_a: GO:0018197 ! peptidyl-aspartic acid modification +is_a: GO:0018315 ! molybdenum incorporation into molybdenum-molybdopterin complex + +[Term] +id: GO:0051218 +name: tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) +namespace: biological_process +def: "The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)." [PDB:1HOH, PMID:12220497, RESID:AA0376] +xref: RESID:AA02376 +is_a: GO:0042042 ! tungsten incorporation into tungsten-molybdopterin complex +is_a: GO:0050844 ! peptidyl-selenocysteine modification + +[Term] +id: GO:0051219 +name: phosphoprotein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphorylated protein." [GOC:ai] +subset: goslim_chembl +synonym: "phosphorylated protein binding" EXACT [] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051220 +name: cytoplasmic sequestering of protein +namespace: biological_process +def: "The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell." [GOC:ai] +synonym: "cytoplasmic retention of protein" EXACT [] +synonym: "cytoplasmic sequestration of protein" EXACT [] +synonym: "cytoplasmic storage of protein" EXACT [] +synonym: "maintenance of protein location in cytoplasm" EXACT [GOC:dph, GOC:tb] +synonym: "retention of protein in cytoplasm" EXACT [] +synonym: "sequestering of protein in cytoplasm" EXACT [] +synonym: "sequestration of protein in cytoplasm" EXACT [] +synonym: "storage of protein in cytoplasm" EXACT [] +is_a: GO:0045185 ! maintenance of protein location + +[Term] +id: GO:0051221 +name: tungsten incorporation into metallo-sulfur cluster +namespace: biological_process +def: "The incorporation of tungsten into a metallo-sulfur cluster." [GOC:ai] +synonym: "tungsten incorporation into metallo-sulphur cluster" EXACT [] +is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster + +[Term] +id: GO:0051222 +name: positive regulation of protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of protein transport" NARROW [] +synonym: "stimulation of protein transport" NARROW [] +synonym: "up regulation of protein transport" EXACT [] +synonym: "up-regulation of protein transport" EXACT [] +synonym: "upregulation of protein transport" EXACT [] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:1904951 ! positive regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015031 ! protein transport +relationship: positively_regulates GO:0015031 ! protein transport + +[Term] +id: GO:0051223 +name: regulation of protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0070201 ! regulation of establishment of protein localization +is_a: GO:0090087 ! regulation of peptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015031 ! protein transport +relationship: regulates GO:0015031 ! protein transport + +[Term] +id: GO:0051224 +name: negative regulation of protein transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of protein transport" EXACT [] +synonym: "down-regulation of protein transport" EXACT [] +synonym: "downregulation of protein transport" EXACT [] +synonym: "inhibition of protein transport" NARROW [] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:1904950 ! negative regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015031 ! protein transport +relationship: negatively_regulates GO:0015031 ! protein transport + +[Term] +id: GO:0051225 +name: spindle assembly +namespace: biological_process +alt_id: GO:0051226 +alt_id: GO:0051227 +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." [GOC:ai, GOC:expert_rg, GOC:mtg_sensu, GOC:tb] +synonym: "bipolar spindle biosynthesis" EXACT [] +synonym: "bipolar spindle formation" EXACT [] +synonym: "spindle biosynthesis" EXACT [] +synonym: "spindle formation" EXACT [] +is_a: GO:0007051 ! spindle organization +is_a: GO:0070925 ! organelle assembly + +[Term] +id: GO:0051228 +name: mitotic spindle disassembly +namespace: biological_process +def: "The controlled breakdown of the spindle during a mitotic cell cycle." [GOC:ai] +synonym: "mitotic spindle breakdown" EXACT [] +synonym: "mitotic spindle catabolism" EXACT [] +synonym: "mitotic spindle degradation" EXACT [] +synonym: "spindle breakdown during mitosis" EXACT [] +synonym: "spindle degradation during mitosis" EXACT [] +synonym: "spindle disassembly during mitosis" EXACT [] +is_a: GO:0007052 ! mitotic spindle organization +is_a: GO:0051230 ! spindle disassembly +intersection_of: GO:0051230 ! spindle disassembly +intersection_of: part_of GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0051229 +name: meiotic spindle disassembly +namespace: biological_process +def: "The controlled breakdown of the spindle during a meiotic cell cycle." [GOC:ai] +synonym: "meiotic spindle breakdown" EXACT [] +synonym: "meiotic spindle catabolism" EXACT [] +synonym: "meiotic spindle degradation" EXACT [] +synonym: "spindle breakdown during meiosis" EXACT [] +synonym: "spindle degradation during meiosis" EXACT [] +synonym: "spindle disassembly during meiosis" EXACT [] +is_a: GO:0000212 ! meiotic spindle organization +is_a: GO:0051230 ! spindle disassembly +intersection_of: GO:0051230 ! spindle disassembly +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051230 +name: spindle disassembly +namespace: biological_process +def: "The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." [GOC:ai] +synonym: "spindle breakdown" EXACT [] +synonym: "spindle catabolism" EXACT [] +synonym: "spindle degradation" EXACT [] +is_a: GO:0007051 ! spindle organization +is_a: GO:1903008 ! organelle disassembly + +[Term] +id: GO:0051231 +name: spindle elongation +namespace: biological_process +def: "The cell cycle process in which the distance is lengthened between poles of the spindle." [GOC:ai] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007051 ! spindle organization +relationship: part_of GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0051232 +name: meiotic spindle elongation +namespace: biological_process +def: "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." [GOC:ai] +synonym: "spindle elongation during meiosis" EXACT [] +is_a: GO:0051231 ! spindle elongation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051231 ! spindle elongation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0000212 ! meiotic spindle organization +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0051233 +name: spindle midzone +namespace: cellular_component +def: "The area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:ai, PMID:15296749] +synonym: "central spindle" EXACT [PMID:14528012] +synonym: "spindle equator" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005819 ! spindle + +[Term] +id: GO:0051234 +name: establishment of localization +namespace: biological_process +def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos] +subset: goslim_agr +subset: goslim_flybase_ribbon +subset: goslim_mouse +subset: goslim_pir +synonym: "establishment of localisation" EXACT [GOC:mah] +is_a: GO:0051179 ! localization + +[Term] +id: GO:0051235 +name: maintenance of location +namespace: biological_process +def: "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of localization" EXACT [] +synonym: "retention" NARROW [] +synonym: "sequestering" NARROW [] +synonym: "storage" NARROW [] +is_a: GO:0051179 ! localization +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0051236 +name: establishment of RNA localization +namespace: biological_process +def: "The directed movement of RNA to a specific location." [GOC:ai] +synonym: "establishment of RNA localisation" EXACT [GOC:mah] +synonym: "RNA positioning" EXACT [] +synonym: "RNA recruitment" EXACT [] +is_a: GO:0051234 ! establishment of localization +relationship: part_of GO:0006403 ! RNA localization + +[Term] +id: GO:0051237 +name: maintenance of RNA location +namespace: biological_process +def: "Any process in which RNA is maintained in a location and prevented from moving elsewhere." [GOC:ai] +synonym: "maintenance of RNA localization" RELATED [GOC:dph, GOC:tb] +synonym: "RNA retention" EXACT [] +is_a: GO:0051235 ! maintenance of location +relationship: part_of GO:0006403 ! RNA localization + +[Term] +id: GO:0051238 +name: sequestering of metal ion +namespace: biological_process +def: "The process of binding or confining metal ions such that they are separated from other components of a biological system." [GOC:ai] +synonym: "metal ion retention" EXACT [] +synonym: "metal ion sequestering" EXACT [] +synonym: "metal ion sequestration" EXACT [] +synonym: "metal ion storage" EXACT [] +synonym: "retention of metal ion" EXACT [] +synonym: "sequestration of metal ion" EXACT [] +synonym: "storage of metal ion" EXACT [] +is_a: GO:0051235 ! maintenance of location + +[Term] +id: GO:0051239 +name: regulation of multicellular organismal process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032501 ! multicellular organismal process +relationship: regulates GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0051240 +name: positive regulation of multicellular organismal process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] +synonym: "activation of multicellular organismal process" NARROW [] +synonym: "stimulation of multicellular organismal process" NARROW [] +synonym: "up regulation of multicellular organismal process" EXACT [] +synonym: "up-regulation of multicellular organismal process" EXACT [] +synonym: "upregulation of multicellular organismal process" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032501 ! multicellular organismal process +relationship: positively_regulates GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0051241 +name: negative regulation of multicellular organismal process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] +synonym: "down regulation of multicellular organismal process" EXACT [] +synonym: "down-regulation of multicellular organismal process" EXACT [] +synonym: "downregulation of multicellular organismal process" EXACT [] +synonym: "inhibition of multicellular organismal process" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032501 ! multicellular organismal process +relationship: negatively_regulates GO:0032501 ! multicellular organismal process + +[Term] +id: GO:0051245 +name: negative regulation of cellular defense response +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of the cellular defense response." [GOC:ai] +synonym: "down regulation of cellular defense response" EXACT [] +synonym: "down-regulation of cellular defense response" EXACT [] +synonym: "downregulation of cellular defense response" EXACT [] +synonym: "inhibition of cellular defense response" NARROW [] +synonym: "negative regulation of cellular defence response" EXACT [] +is_a: GO:0010185 ! regulation of cellular defense response +is_a: GO:0031348 ! negative regulation of defense response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006968 ! cellular defense response +relationship: negatively_regulates GO:0006968 ! cellular defense response + +[Term] +id: GO:0051246 +name: regulation of protein metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] +synonym: "regulation of protein metabolism" EXACT [] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019538 ! protein metabolic process +relationship: regulates GO:0019538 ! protein metabolic process + +[Term] +id: GO:0051247 +name: positive regulation of protein metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] +synonym: "activation of protein metabolic process" NARROW [] +synonym: "positive regulation of protein metabolism" EXACT [] +synonym: "stimulation of protein metabolic process" NARROW [] +synonym: "up regulation of protein metabolic process" EXACT [] +synonym: "up-regulation of protein metabolic process" EXACT [] +synonym: "upregulation of protein metabolic process" EXACT [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019538 ! protein metabolic process +relationship: positively_regulates GO:0019538 ! protein metabolic process + +[Term] +id: GO:0051248 +name: negative regulation of protein metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai] +synonym: "down regulation of protein metabolic process" EXACT [] +synonym: "down-regulation of protein metabolic process" EXACT [] +synonym: "downregulation of protein metabolic process" EXACT [] +synonym: "inhibition of protein metabolic process" NARROW [] +synonym: "negative regulation of protein metabolism" EXACT [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019538 ! protein metabolic process +relationship: negatively_regulates GO:0019538 ! protein metabolic process + +[Term] +id: GO:0051249 +name: regulation of lymphocyte activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046649 ! lymphocyte activation +relationship: regulates GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0051250 +name: negative regulation of lymphocyte activation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] +synonym: "down regulation of lymphocyte activation" EXACT [] +synonym: "down-regulation of lymphocyte activation" EXACT [] +synonym: "downregulation of lymphocyte activation" EXACT [] +synonym: "inhibition of lymphocyte activation" NARROW [] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046649 ! lymphocyte activation +relationship: negatively_regulates GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0051251 +name: positive regulation of lymphocyte activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] +synonym: "activation of lymphocyte activation" NARROW [] +synonym: "stimulation of lymphocyte activation" NARROW [] +synonym: "up regulation of lymphocyte activation" EXACT [] +synonym: "up-regulation of lymphocyte activation" EXACT [] +synonym: "upregulation of lymphocyte activation" EXACT [] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046649 ! lymphocyte activation +relationship: positively_regulates GO:0046649 ! lymphocyte activation + +[Term] +id: GO:0051252 +name: regulation of RNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] +synonym: "regulation of RNA metabolism" EXACT [] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016070 ! RNA metabolic process +relationship: regulates GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0051253 +name: negative regulation of RNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] +synonym: "down regulation of RNA metabolic process" EXACT [] +synonym: "down-regulation of RNA metabolic process" EXACT [] +synonym: "downregulation of RNA metabolic process" EXACT [] +synonym: "inhibition of RNA metabolic process" NARROW [] +synonym: "negative regulation of RNA metabolism" EXACT [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016070 ! RNA metabolic process +relationship: negatively_regulates GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0051254 +name: positive regulation of RNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] +synonym: "activation of RNA metabolic process" NARROW [] +synonym: "positive regulation of RNA metabolism" EXACT [] +synonym: "stimulation of RNA metabolic process" NARROW [] +synonym: "up regulation of RNA metabolic process" EXACT [] +synonym: "up-regulation of RNA metabolic process" EXACT [] +synonym: "upregulation of RNA metabolic process" EXACT [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016070 ! RNA metabolic process +relationship: positively_regulates GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0051255 +name: spindle midzone assembly +namespace: biological_process +def: "The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:ai, PMID:15296749] +synonym: "spindle midzone biogenesis" EXACT [] +synonym: "spindle midzone biosynthesis" EXACT [] +synonym: "spindle midzone formation" EXACT [] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:0022402 ! cell cycle process +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0051225 ! spindle assembly + +[Term] +id: GO:0051256 +name: mitotic spindle midzone assembly +namespace: biological_process +def: "The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone." [GOC:mtg_cell_cycle, GOC:vw, PMID:24239120] +synonym: "mitotic spindle midzone biogenesis" EXACT [] +synonym: "mitotic spindle midzone biosynthesis" EXACT [] +synonym: "mitotic spindle midzone formation" EXACT [] +synonym: "spindle midzone assembly involved in mitosis" EXACT [] +synonym: "spindle midzone biogenesis involved in mitosis" EXACT [] +synonym: "spindle midzone formation involved in mitosis" EXACT [] +is_a: GO:0051255 ! spindle midzone assembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051255 ! spindle midzone assembly +intersection_of: part_of GO:0140014 ! mitotic nuclear division +relationship: part_of GO:0000022 ! mitotic spindle elongation +relationship: part_of GO:0090307 ! mitotic spindle assembly + +[Term] +id: GO:0051257 +name: meiotic spindle midzone assembly +namespace: biological_process +def: "The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis." [GOC:ai, GOC:expert_rg, GOC:tb] +synonym: "meiotic spindle midzone biogenesis" EXACT [] +synonym: "meiotic spindle midzone biosynthesis" EXACT [] +synonym: "meiotic spindle midzone formation" EXACT [] +synonym: "spindle midzone assembly involved in meiosis" EXACT [] +synonym: "spindle midzone biogenesis involved in meiosis" EXACT [] +synonym: "spindle midzone biosynthesis involved in meiosis" EXACT [] +synonym: "spindle midzone formation involved in meiosis" EXACT [] +is_a: GO:0051255 ! spindle midzone assembly +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051255 ! spindle midzone assembly +intersection_of: part_of GO:0140013 ! meiotic nuclear division +relationship: part_of GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0051258 +name: protein polymerization +namespace: biological_process +def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] +subset: goslim_pir +synonym: "protein polymer biosynthesis" EXACT [] +synonym: "protein polymer biosynthetic process" EXACT [] +synonym: "protein polymer formation" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0051259 +name: protein complex oligomerization +namespace: biological_process +alt_id: GO:0035786 +def: "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." [GOC:ai, PMID:18293929] +synonym: "protein multimerization" RELATED [GOC:bf] +synonym: "protein oligomer assembly" EXACT [] +synonym: "protein oligomer biosynthesis" BROAD [] +synonym: "protein oligomer biosynthetic process" BROAD [] +synonym: "protein oligomer formation" EXACT [] +synonym: "protein oligomerization" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2011-04-05T09:57:49Z + +[Term] +id: GO:0051260 +name: protein homooligomerization +namespace: biological_process +def: "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." [GOC:ai] +synonym: "protein homooligomer assembly" EXACT [] +synonym: "protein homooligomer biosynthesis" EXACT [] +synonym: "protein homooligomer biosynthetic process" EXACT [] +synonym: "protein homooligomer formation" EXACT [] +synonym: "protein homooligomerization activity" RELATED [] +is_a: GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0051261 +name: protein depolymerization +namespace: biological_process +def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai] +subset: goslim_pir +synonym: "protein polymer breakdown" EXACT [] +synonym: "protein polymer catabolic process" EXACT [] +synonym: "protein polymer catabolism" EXACT [] +synonym: "protein polymer degradation" EXACT [] +is_a: GO:0043624 ! cellular protein complex disassembly + +[Term] +id: GO:0051262 +name: protein tetramerization +namespace: biological_process +def: "The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits." [GOC:ecd] +synonym: "protein tetramer assembly" EXACT [] +synonym: "protein tetramer biosynthesis" EXACT [] +synonym: "protein tetramer biosynthetic process" EXACT [] +synonym: "protein tetramer formation" EXACT [] +is_a: GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0051263 +name: microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine +namespace: biological_process +def: "The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain." [RESID:AA0374] +synonym: "microcin E492 anabolism by siderophore ester modification of peptidyl-serine" EXACT [] +synonym: "microcin E492 formation by siderophore ester modification of peptidyl-serine" EXACT [] +synonym: "microcin E492 synthesis by siderophore ester modification of peptidyl-serine" EXACT [] +xref: RESID:AA0374 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0018350 ! protein esterification + +[Term] +id: GO:0051264 +name: mono-olein transacylation activity +namespace: molecular_function +def: "Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol." [GOC:ai, PMID:15364929] +synonym: "acyl-CoA-independent mono-olein transacylation" EXACT [] +synonym: "MOG transacylation" EXACT [] +synonym: "mono-oleoylglycerol O-acyltransferase activity" EXACT [] +synonym: "mono-oleoylglycerol transacylase activity" EXACT [] +synonym: "monoolein transacylation" EXACT [] +synonym: "monooleoylglycerol O-acyltransferase activity" EXACT [] +synonym: "monooleoylglycerol transacylase activity" EXACT [] +is_a: GO:0016411 ! acylglycerol O-acyltransferase activity + +[Term] +id: GO:0051265 +name: diolein transacylation activity +namespace: molecular_function +def: "Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein." [GOC:ai, PMID:15364929] +synonym: "acyl-CoA-independent diolein transacylation" EXACT [] +synonym: "dioleoylglycerol O-acyltransferase activity" EXACT [] +synonym: "dioleoylglycerol transacylase activity" EXACT [] +synonym: "DOG transacylation" EXACT [] +is_a: GO:0016411 ! acylglycerol O-acyltransferase activity + +[Term] +id: GO:0051266 +name: sirohydrochlorin ferrochelatase activity +namespace: molecular_function +def: "Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin." [EC:4.99.1.4, RHEA:24360] +synonym: "CysG" RELATED [EC:4.99.1.4] +synonym: "Met8P" RELATED [EC:4.99.1.4] +synonym: "SirB" RELATED [EC:4.99.1.4] +synonym: "siroheme ferro-lyase (sirohydrochlorin-forming)" EXACT [EC:4.99.1.4] +synonym: "siroheme synthase activity" BROAD [] +synonym: "sirohydrochlorin ferro-lyase activity" EXACT [] +xref: EC:4.99.1.4 +xref: KEGG_REACTION:R02864 +xref: MetaCyc:SIROHEME-FERROCHELAT-RXN +xref: RHEA:24360 +is_a: GO:0004325 ! ferrochelatase activity + +[Term] +id: GO:0051267 +name: CP2 mannose-ethanolamine phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2." [PMID:14985347, PMID:15452134] +synonym: "addition of ethanolamine phosphate to mannose of GPI precursor CP2" EXACT [] +synonym: "CP2 ethanolamine phosphate transferase activity" EXACT [] +synonym: "CP2 EtN-P transferase activity" EXACT [] +synonym: "CP2 phosphoethanolamine transferase activity" EXACT [] +synonym: "gpi7 activity" RELATED [] +is_a: GO:0051377 ! mannose-ethanolamine phosphotransferase activity + +[Term] +id: GO:0051268 +name: alpha-keto amide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic." [GOC:ai, PMID:15564669] +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0051269 +name: alpha-keto ester reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic." [GOC:ai, PMID:15564669] +xref: EC:1.2 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0051270 +name: regulation of cellular component movement +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl] +synonym: "regulation of cell movement" RELATED [] +synonym: "regulation of cellular component motion" EXACT [GOC:mah] +is_a: GO:0032879 ! regulation of localization +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006928 ! movement of cell or subcellular component +relationship: regulates GO:0006928 ! movement of cell or subcellular component + +[Term] +id: GO:0051271 +name: negative regulation of cellular component movement +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl] +synonym: "negative regulation of cellular component motion" EXACT [GOC:mah] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006928 ! movement of cell or subcellular component +relationship: negatively_regulates GO:0006928 ! movement of cell or subcellular component + +[Term] +id: GO:0051272 +name: positive regulation of cellular component movement +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the movement of a cellular component." [GOC:ai, GOC:dph, GOC:jl] +synonym: "positive regulation of cellular component motion" EXACT [GOC:mah] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006928 ! movement of cell or subcellular component +relationship: positively_regulates GO:0006928 ! movement of cell or subcellular component + +[Term] +id: GO:0051273 +name: beta-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds." [GOC:ai] +synonym: "beta-glucan metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process + +[Term] +id: GO:0051274 +name: beta-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-glucans." [GOC:ai] +synonym: "beta-glucan anabolism" EXACT [] +synonym: "beta-glucan biosynthesis" EXACT [] +synonym: "beta-glucan formation" EXACT [] +synonym: "beta-glucan synthesis" EXACT [] +is_a: GO:0009250 ! glucan biosynthetic process +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0051275 +name: beta-glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-glucans." [GOC:ai] +synonym: "beta-glucan breakdown" EXACT [] +synonym: "beta-glucan catabolism" EXACT [] +synonym: "beta-glucan degradation" EXACT [] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0051273 ! beta-glucan metabolic process + +[Term] +id: GO:0051276 +name: chromosome organization +namespace: biological_process +alt_id: GO:0007001 +alt_id: GO:0051277 +def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +synonym: "chromosome organisation" EXACT [] +synonym: "chromosome organization and biogenesis" RELATED [GOC:mah] +synonym: "maintenance of genome integrity" RELATED [] +synonym: "nuclear genome maintenance" RELATED [] +is_a: GO:0006996 ! organelle organization + +[Term] +id: GO:0051278 +name: fungal-type cell wall polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall." [GOC:ai, GOC:mtg_sensu] +synonym: "cell wall polysaccharide anabolism" BROAD [] +synonym: "cell wall polysaccharide formation" BROAD [] +synonym: "cell wall polysaccharide synthesis" BROAD [] +synonym: "chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process" NARROW [] +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process +is_a: GO:0071966 ! fungal-type cell wall polysaccharide metabolic process +relationship: part_of GO:0009272 ! fungal-type cell wall biogenesis + +[Term] +id: GO:0051279 +name: regulation of release of sequestered calcium ion into cytosol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai, GOC:tb] +synonym: "regulation of calcium ion (Ca2+) mobilization" EXACT [] +synonym: "regulation of calcium mobilization" EXACT [] +synonym: "regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" EXACT [] +synonym: "regulation of cytoplasmic release of stored calcium ion (Ca2+)" EXACT [] +synonym: "regulation of release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "regulation of release of stored calcium ion (Ca2+)" BROAD [] +synonym: "regulation of release of stored calcium ion (Ca2+) into cytoplasm" EXACT [] +synonym: "regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] +is_a: GO:0010522 ! regulation of calcium ion transport into cytosol +is_a: GO:0051282 ! regulation of sequestering of calcium ion +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051209 ! release of sequestered calcium ion into cytosol +relationship: regulates GO:0051209 ! release of sequestered calcium ion into cytosol + +[Term] +id: GO:0051280 +name: negative regulation of release of sequestered calcium ion into cytosol +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai] +synonym: "down regulation of release of sequestered calcium ion into cytosol" EXACT [] +synonym: "down-regulation of release of sequestered calcium ion into cytosol" EXACT [] +synonym: "downregulation of release of sequestered calcium ion into cytosol" EXACT [] +synonym: "inhibition of release of sequestered calcium ion into cytosol" NARROW [] +synonym: "negative regulation of calcium ion (Ca2+) mobilization" BROAD [] +synonym: "negative regulation of calcium mobilization" BROAD [] +synonym: "negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "negative regulation of cytoplasmic release of stored calcium ion (Ca2+)" BROAD [] +synonym: "negative regulation of cytosolic release of sequestered calcium ion (Ca2+)" EXACT [] +synonym: "negative regulation of cytosolic release of stored calcium ion (Ca2+)" EXACT [] +synonym: "negative regulation of release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "negative regulation of release of sequestered calcium ion into cytoplasm" BROAD [] +synonym: "negative regulation of release of stored calcium ion (Ca2+)" BROAD [] +synonym: "negative regulation of release of stored calcium ion (Ca2+) into cytoplasm" BROAD [] +synonym: "negative regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] +is_a: GO:0010523 ! negative regulation of calcium ion transport into cytosol +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +is_a: GO:0051284 ! positive regulation of sequestering of calcium ion +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051209 ! release of sequestered calcium ion into cytosol +relationship: negatively_regulates GO:0051209 ! release of sequestered calcium ion into cytosol + +[Term] +id: GO:0051281 +name: positive regulation of release of sequestered calcium ion into cytosol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai] +synonym: "activation of release of sequestered calcium ion into cytosol" NARROW [] +synonym: "positive regulation of calcium ion (Ca2+) mobilization" BROAD [] +synonym: "positive regulation of calcium mobilization" BROAD [] +synonym: "positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "positive regulation of cytoplasmic release of stored calcium ion (Ca2+)" BROAD [] +synonym: "positive regulation of cytosolic release of sequestered calcium ion (Ca2+)" EXACT [] +synonym: "positive regulation of cytosolic release of stored calcium ion (Ca2+)" EXACT [] +synonym: "positive regulation of release of sequestered calcium ion (Ca2+)" BROAD [] +synonym: "positive regulation of release of sequestered calcium ion into cytoplasm" BROAD [] +synonym: "positive regulation of release of stored calcium ion (Ca2+)" BROAD [] +synonym: "positive regulation of release of stored calcium ion (Ca2+) into cytoplasm" BROAD [] +synonym: "positive regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] +synonym: "stimulation of release of sequestered calcium ion into cytosol" NARROW [] +synonym: "up regulation of release of sequestered calcium ion into cytosol" EXACT [] +synonym: "up-regulation of release of sequestered calcium ion into cytosol" EXACT [] +synonym: "upregulation of release of sequestered calcium ion into cytosol" EXACT [] +is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051209 ! release of sequestered calcium ion into cytosol +relationship: positively_regulates GO:0051209 ! release of sequestered calcium ion into cytosol + +[Term] +id: GO:0051282 +name: regulation of sequestering of calcium ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system." [GOC:ai] +synonym: "regulation of calcium ion (Ca2+) retention" EXACT [] +synonym: "regulation of calcium ion (Ca2+) sequestering" EXACT [] +synonym: "regulation of calcium ion (Ca2+) sequestration" EXACT [] +synonym: "regulation of calcium ion (Ca2+) storage" EXACT [] +synonym: "regulation of retention of calcium ion (Ca2+)" EXACT [] +synonym: "regulation of sequestering of calcium ion (Ca2+)" EXACT [] +synonym: "regulation of sequestration of calcium ion (Ca2+)" EXACT [] +synonym: "regulation of storage of calcium ion (Ca2+)" EXACT [] +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051208 ! sequestering of calcium ion +relationship: regulates GO:0051208 ! sequestering of calcium ion + +[Term] +id: GO:0051283 +name: negative regulation of sequestering of calcium ion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system." [GOC:ai] +synonym: "down regulation of sequestering of calcium ion" EXACT [] +synonym: "down-regulation of sequestering of calcium ion" EXACT [] +synonym: "downregulation of sequestering of calcium ion" EXACT [] +synonym: "inhibition of sequestering of calcium ion" NARROW [] +synonym: "negative regulation of calcium ion (Ca2+) retention" EXACT [] +synonym: "negative regulation of calcium ion (Ca2+) sequestering" EXACT [] +synonym: "negative regulation of calcium ion (Ca2+) sequestration" EXACT [] +synonym: "negative regulation of calcium ion (Ca2+) storage" EXACT [] +synonym: "negative regulation of retention of calcium ion (Ca2+)" EXACT [] +synonym: "negative regulation of sequestering of calcium ion (Ca2+)" EXACT [] +synonym: "negative regulation of sequestration of calcium ion (Ca2+)" EXACT [] +synonym: "negative regulation of storage of calcium ion (Ca2+)" EXACT [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051282 ! regulation of sequestering of calcium ion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051208 ! sequestering of calcium ion +relationship: negatively_regulates GO:0051208 ! sequestering of calcium ion + +[Term] +id: GO:0051284 +name: positive regulation of sequestering of calcium ion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system." [GOC:ai] +synonym: "activation of sequestering of calcium ion" NARROW [] +synonym: "positive regulation of calcium ion (Ca2+) retention" EXACT [] +synonym: "positive regulation of calcium ion (Ca2+) sequestering" EXACT [] +synonym: "positive regulation of calcium ion (Ca2+) sequestration" EXACT [] +synonym: "positive regulation of calcium ion (Ca2+) storage" EXACT [] +synonym: "positive regulation of retention of calcium ion (Ca2+)" EXACT [] +synonym: "positive regulation of sequestering of calcium ion (Ca2+)" EXACT [] +synonym: "positive regulation of sequestration of calcium ion (Ca2+)" EXACT [] +synonym: "positive regulation of storage of calcium ion (Ca2+)" EXACT [] +synonym: "stimulation of sequestering of calcium ion" NARROW [] +synonym: "up regulation of sequestering of calcium ion" EXACT [] +synonym: "up-regulation of sequestering of calcium ion" EXACT [] +synonym: "upregulation of sequestering of calcium ion" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051282 ! regulation of sequestering of calcium ion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051208 ! sequestering of calcium ion +relationship: positively_regulates GO:0051208 ! sequestering of calcium ion + +[Term] +id: GO:0051285 +name: cell cortex of cell tip +namespace: cellular_component +def: "The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell." [GOC:ai] +synonym: "cell cortex of cell end" EXACT [] +is_a: GO:0099738 ! cell cortex region +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0051286 ! cell tip +relationship: part_of GO:0051286 ! cell tip + +[Term] +id: GO:0051286 +name: cell tip +namespace: cellular_component +def: "The region at the end of the longest axis of a cylindrical or elongated cell." [GOC:ai, GOC:mah] +comment: Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to the thin ends of elongated cells, such as the ends of axons or dendrites. +synonym: "cell end" EXACT [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0051287 +name: NAD binding +namespace: molecular_function +alt_id: GO:0051288 +def: "Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH." [GOC:ai] +subset: goslim_chembl +synonym: "NAD or NADH binding" RELATED [GOC:mah] +synonym: "NAD+ or NADH binding" RELATED [] +synonym: "nicotinamide adenine dinucleotide binding" EXACT [] +is_a: GO:0000166 ! nucleotide binding +is_a: GO:0050662 ! coenzyme binding + +[Term] +id: GO:0051289 +name: protein homotetramerization +namespace: biological_process +def: "The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits." [GOC:go_curators] +synonym: "protein homotetramer assembly" EXACT [] +synonym: "protein homotetramer biosynthesis" EXACT [] +synonym: "protein homotetramer biosynthetic process" EXACT [] +synonym: "protein homotetramer formation" EXACT [] +is_a: GO:0051260 ! protein homooligomerization +is_a: GO:0051262 ! protein tetramerization + +[Term] +id: GO:0051290 +name: protein heterotetramerization +namespace: biological_process +def: "The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical." [GOC:go_curators] +synonym: "protein heterotetramer assembly" EXACT [] +synonym: "protein heterotetramer biosynthesis" EXACT [] +synonym: "protein heterotetramer biosynthetic process" EXACT [] +synonym: "protein heterotetramer formation" EXACT [] +is_a: GO:0051262 ! protein tetramerization +is_a: GO:0051291 ! protein heterooligomerization + +[Term] +id: GO:0051291 +name: protein heterooligomerization +namespace: biological_process +def: "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." [GOC:ai] +synonym: "protein heterooligomer assembly" EXACT [] +synonym: "protein heterooligomer biosynthesis" EXACT [] +synonym: "protein heterooligomer biosynthetic process" EXACT [] +synonym: "protein heterooligomer formation" EXACT [] +is_a: GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0051292 +name: nuclear pore complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex." [GOC:ai, GOC:mah] +synonym: "NPC assembly" EXACT [] +synonym: "nuclear pore assembly" EXACT [] +synonym: "nuclear pore biogenesis" EXACT [] +synonym: "nuclear pore biosynthesis" EXACT [] +synonym: "nuclear pore complex biogenesis" EXACT [] +synonym: "nuclear pore complex biosynthesis" EXACT [] +synonym: "nuclear pore complex formation" EXACT [] +synonym: "nuclear pore formation" EXACT [] +is_a: GO:0006999 ! nuclear pore organization +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0046931 ! pore complex assembly + +[Term] +id: GO:0051293 +name: establishment of spindle localization +namespace: biological_process +def: "The directed movement of the spindle to a specific location in the cell." [GOC:ai] +synonym: "establishment of spindle localisation" EXACT [GOC:mah] +synonym: "spindle positioning" EXACT [] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051653 ! spindle localization +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051294 +name: establishment of spindle orientation +namespace: biological_process +def: "Any process that set the alignment of spindle relative to other cellular structures." [GOC:ai] +synonym: "orienting of spindle" EXACT [] +synonym: "spindle orientation" EXACT [] +is_a: GO:0051293 ! establishment of spindle localization +relationship: part_of GO:0030010 ! establishment of cell polarity + +[Term] +id: GO:0051295 +name: establishment of meiotic spindle localization +namespace: biological_process +def: "The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs." [GOC:ai] +synonym: "establishment of meiotic spindle localisation" EXACT [GOC:mah] +synonym: "meiotic spindle positioning" EXACT [] +synonym: "spindle positioning during meiosis" RELATED [] +synonym: "spindle positioning involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051293 ! establishment of spindle localization +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051293 ! establishment of spindle localization +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051296 +name: establishment of meiotic spindle orientation +namespace: biological_process +def: "Any process that set the alignment of meiotic spindle relative to other cellular structures." [GOC:ai] +synonym: "establishment of spindle orientation during meiosis" RELATED [] +synonym: "establishment of spindle orientation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "meiotic spindle orientation" EXACT [] +synonym: "orienting of meiotic spindle" EXACT [] +is_a: GO:0051294 ! establishment of spindle orientation +is_a: GO:0051295 ! establishment of meiotic spindle localization +intersection_of: GO:0051294 ! establishment of spindle orientation +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051298 +name: centrosome duplication +namespace: biological_process +def: "The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:ai] +synonym: "centrosome replication" EXACT [] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007098 ! centrosome cycle + +[Term] +id: GO:0051299 +name: centrosome separation +namespace: biological_process +def: "The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [GOC:ai] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007098 ! centrosome cycle + +[Term] +id: GO:0051300 +name: spindle pole body organization +namespace: biological_process +alt_id: GO:0051426 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "SPB maturation" RELATED [GOC:vw] +synonym: "SPB organization" EXACT [] +synonym: "spindle pole body maturation" RELATED [GOC:vw] +synonym: "spindle pole body organisation" EXACT [] +synonym: "spindle pole body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0031023 ! microtubule organizing center organization + +[Term] +id: GO:0051301 +name: cell division +namespace: biological_process +def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr] +comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division. +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +xref: Wikipedia:Cell_division +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0051302 +name: regulation of cell division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051301 ! cell division +relationship: regulates GO:0051301 ! cell division + +[Term] +id: GO:0051303 +name: establishment of chromosome localization +namespace: biological_process +def: "The directed movement of a chromosome to a specific location." [GOC:ai] +synonym: "chromosome positioning" EXACT [] +synonym: "establishment of chromosome localisation" EXACT [GOC:mah] +is_a: GO:0050000 ! chromosome localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051304 +name: chromosome separation +namespace: biological_process +alt_id: GO:0034500 +def: "The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)." [GOC:ai, GOC:lb, GOC:mah, GOC:mtg_cell_cycle, PMID:20352243] +synonym: "chromatid release" RELATED [GOC:lb, GOC:mah, PMID:20352243] +synonym: "rDNA separation" NARROW [] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007059 ! chromosome segregation + +[Term] +id: GO:0051305 +name: chromosome movement towards spindle pole +namespace: biological_process +def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes." [GOC:ai] +synonym: "chromosome migration to spindle pole" EXACT [] +synonym: "chromosome movement" BROAD [] +synonym: "chromosome movement to spindle pole" EXACT [] +is_a: GO:0007018 ! microtubule-based movement +is_a: GO:0022402 ! cell cycle process +is_a: GO:0051303 ! establishment of chromosome localization +relationship: part_of GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0051306 +name: mitotic sister chromatid separation +namespace: biological_process +def: "The process in which sister chromatids are physically detached from each other during mitosis." [GOC:ai] +synonym: "chromosome separation during mitosis" RELATED [] +synonym: "mitotic chromosome separation" RELATED [] +synonym: "mitotic sister chromatid resolution" EXACT [GOC:mah] +synonym: "sister chromatid separation during mitosis" EXACT [] +is_a: GO:0051304 ! chromosome separation +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0000070 ! mitotic sister chromatid segregation + +[Term] +id: GO:0051307 +name: meiotic chromosome separation +namespace: biological_process +def: "The process in which chromosomes are physically detached from each other during meiosis." [GOC:ai] +synonym: "chromosome separation during meiosis" EXACT [] +synonym: "meiotic chromosome resolution" EXACT [GOC:mah] +is_a: GO:0051304 ! chromosome separation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051304 ! chromosome separation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0051308 +name: male meiosis chromosome separation +namespace: biological_process +def: "The process in which paired chromosomes are physically detached from each other during male meiosis." [GOC:ai] +synonym: "chromosome separation during male meiosis" EXACT [] +synonym: "male meiosis chromosome resolution" EXACT [GOC:mah] +is_a: GO:0007060 ! male meiosis chromosome segregation +is_a: GO:0051307 ! meiotic chromosome separation +intersection_of: GO:0051304 ! chromosome separation +intersection_of: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0051309 +name: female meiosis chromosome separation +namespace: biological_process +def: "The process in which paired chromosomes are physically detached from each other during female meiosis." [GOC:ai] +synonym: "chromosome separation during female meiosis" EXACT [] +synonym: "female meiosis chromosome resolution" EXACT [GOC:mah] +is_a: GO:0016321 ! female meiosis chromosome segregation +is_a: GO:0051307 ! meiotic chromosome separation +intersection_of: GO:0051304 ! chromosome separation +intersection_of: part_of GO:0007143 ! female meiotic nuclear division + +[Term] +id: GO:0051310 +name: metaphase plate congression +namespace: biological_process +def: "The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle." [GOC:ai] +synonym: "chromosome congression" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0051303 ! establishment of chromosome localization +relationship: part_of GO:0098813 ! nuclear chromosome segregation + +[Term] +id: GO:0051311 +name: meiotic metaphase plate congression +namespace: biological_process +def: "The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis." [GOC:ai] +synonym: "metaphase plate congression during meiosis" EXACT [] +is_a: GO:0051310 ! metaphase plate congression +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051310 ! metaphase plate congression +intersection_of: part_of GO:0051321 ! meiotic cell cycle +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0051312 +name: chromosome decondensation +namespace: biological_process +def: "The alteration of chromosome structure from the condensed form to a relaxed disperse form." [GOC:ai] +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0051315 +name: attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +alt_id: GO:0051314 +def: "The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression." [GOC:ai, GOC:clt, GOC:dph, GOC:tb, PMID:26258632, PMID:26705896] +comment: This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation) +synonym: "attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [] +synonym: "attachment of spindle microtubules to mitotic chromosome" EXACT [] +synonym: "mitotic bipolar attachment" RELATED [GOC:vw] +is_a: GO:0008608 ! attachment of spindle microtubules to kinetochore +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0008608 ! attachment of spindle microtubules to kinetochore +intersection_of: part_of GO:0007080 ! mitotic metaphase plate congression +relationship: part_of GO:0007080 ! mitotic metaphase plate congression + +[Term] +id: GO:0051316 +name: attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation +namespace: biological_process +alt_id: GO:0051317 +def: "The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation." [GOC:ai, GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore during meiosis" RELATED [] +synonym: "attachment of spindle microtubules to kinetochore during meiotic chromosome segregation" RELATED [GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to meiotic chromosome" EXACT [] +is_a: GO:0008608 ! attachment of spindle microtubules to kinetochore +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0008608 ! attachment of spindle microtubules to kinetochore +intersection_of: part_of GO:0045132 ! meiotic chromosome segregation +relationship: part_of GO:0045132 ! meiotic chromosome segregation + +[Term] +id: GO:0051318 +name: G1 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:G1_phase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0051325 ! interphase + +[Term] +id: GO:0051319 +name: G2 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:G2_phase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0051325 ! interphase + +[Term] +id: GO:0051320 +name: S phase +namespace: biological_process +def: "The cell cycle phase, following G1, during which DNA synthesis takes place." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "S-phase" EXACT [] +xref: Wikipedia:S_phase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0051325 ! interphase + +[Term] +id: GO:0051321 +name: meiotic cell cycle +namespace: biological_process +alt_id: GO:0007126 +def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai] +subset: goslim_drosophila +subset: goslim_yeast +synonym: "meiosis" RELATED [] +xref: Wikipedia:Meiosis +is_a: GO:0007049 ! cell cycle +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0007049 ! cell cycle +intersection_of: has_part GO:0140013 ! meiotic nuclear division +relationship: has_part GO:0140013 ! meiotic nuclear division + +[Term] +id: GO:0051322 +name: anaphase +namespace: biological_process +def: "The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Anaphase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0000279 ! M phase + +[Term] +id: GO:0051323 +name: metaphase +namespace: biological_process +def: "The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Metaphase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0000279 ! M phase + +[Term] +id: GO:0051324 +name: prophase +namespace: biological_process +def: "The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Prophase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0000279 ! M phase + +[Term] +id: GO:0051325 +name: interphase +namespace: biological_process +def: "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "karyostasis" EXACT [] +synonym: "resting phase" BROAD [] +xref: Wikipedia:Interphase +is_a: GO:0022403 ! cell cycle phase + +[Term] +id: GO:0051326 +name: telophase +namespace: biological_process +def: "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [GOC:mtg_cell_cycle] +comment: note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +xref: Wikipedia:Telophase +is_a: GO:0022403 ! cell cycle phase +relationship: part_of GO:0000279 ! M phase + +[Term] +id: GO:0051327 +name: meiotic M phase +namespace: biological_process +def: "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "M phase of meiotic cell cycle" EXACT [] +is_a: GO:0000279 ! M phase +is_a: GO:0098762 ! meiotic cell cycle phase +intersection_of: GO:0000279 ! M phase +intersection_of: happens_during GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051328 +name: meiotic interphase +namespace: biological_process +def: "The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "interphase of meiotic cell cycle" EXACT [] +is_a: GO:0051325 ! interphase +is_a: GO:0098762 ! meiotic cell cycle phase +intersection_of: GO:0051325 ! interphase +intersection_of: happens_during GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051329 +name: mitotic interphase +namespace: biological_process +def: "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "interphase of mitotic cell cycle" EXACT [] +is_a: GO:0051325 ! interphase +is_a: GO:0098763 ! mitotic cell cycle phase +intersection_of: GO:0051325 ! interphase +intersection_of: happens_during GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0051330 +name: meiotic G1 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "G1 phase of meiotic cell cycle" EXACT [] +is_a: GO:0051318 ! G1 phase +relationship: part_of GO:0051328 ! meiotic interphase + +[Term] +id: GO:0051331 +name: meiotic G2 phase +namespace: biological_process +def: "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "G2 phase of meiotic cell cycle" EXACT [] +is_a: GO:0051319 ! G2 phase +relationship: part_of GO:0051328 ! meiotic interphase + +[Term] +id: GO:0051332 +name: meiotic S phase +namespace: biological_process +def: "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +synonym: "S phase of meiotic cell cycle" EXACT [] +synonym: "S-phase of meiotic cell cycle" EXACT [] +is_a: GO:0051320 ! S phase +relationship: part_of GO:0051328 ! meiotic interphase + +[Term] +id: GO:0051333 +name: meiotic nuclear envelope reassembly +namespace: biological_process +def: "The cell cycle process in which the reformation of the nuclear envelope during meiosis occurs." [GOC:ai] +is_a: GO:0031468 ! nuclear envelope reassembly +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0031468 ! nuclear envelope reassembly +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051334 +name: meiosis I nuclear envelope reassembly +namespace: biological_process +def: "The reformation of the nuclear envelope during meiosis I." [GOC:ai] +is_a: GO:0051333 ! meiotic nuclear envelope reassembly +intersection_of: GO:0031468 ! nuclear envelope reassembly +intersection_of: part_of GO:0007127 ! meiosis I +relationship: part_of GO:0007127 ! meiosis I + +[Term] +id: GO:0051335 +name: meiosis II nuclear envelope reassembly +namespace: biological_process +def: "The reformation of the nuclear envelope during meiosis II." [GOC:ai] +is_a: GO:0051333 ! meiotic nuclear envelope reassembly +intersection_of: GO:0031468 ! nuclear envelope reassembly +intersection_of: part_of GO:0007135 ! meiosis II +relationship: part_of GO:0007135 ! meiosis II + +[Term] +id: GO:0051336 +name: regulation of hydrolase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [EC:3.-.-.-, GOC:ai] +synonym: "hydrolase regulator" EXACT [] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016787 ! hydrolase activity +relationship: regulates GO:0016787 ! hydrolase activity + +[Term] +id: GO:0051337 +name: amitosis +namespace: biological_process +def: "Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation." [GOC:curators, ISBN:0721662544] +synonym: "direct nuclear division" EXACT [] +synonym: "Remak nuclear division" EXACT [] +is_a: GO:0000280 ! nuclear division + +[Term] +id: GO:0051338 +name: regulation of transferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [EC:2.-.-.-, GOC:ai] +comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. +subset: gocheck_do_not_manually_annotate +synonym: "transferase regulator" EXACT [] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016740 ! transferase activity +relationship: regulates GO:0016740 ! transferase activity + +[Term] +id: GO:0051339 +name: regulation of lyase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [EC:4.-.-.-, GOC:ai] +synonym: "lyase regulator" EXACT [] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016829 ! lyase activity +relationship: regulates GO:0016829 ! lyase activity + +[Term] +id: GO:0051340 +name: regulation of ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6." [EC:6.-.-.-, GOC:ai] +synonym: "ligase regulator" EXACT [] +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016874 ! ligase activity +relationship: regulates GO:0016874 ! ligase activity + +[Term] +id: GO:0051341 +name: regulation of oxidoreductase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced." [EC:1.-.-.-, GOC:ai] +synonym: "oxidoreductase regulator" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016491 ! oxidoreductase activity +relationship: regulates GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0051342 +name: regulation of cyclic-nucleotide phosphodiesterase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate." [EC:3.1.4.17, GOC:ai, GOC:tb] +synonym: "3',5' cyclic nucleotide phosphodiesterase regulator" EXACT [] +synonym: "3',5'-cyclic-AMP phosphodiesterase regulator" NARROW [] +synonym: "cAMP phosphodiesterase regulator" NARROW [] +synonym: "phosphodiesterase regulator" RELATED [] +synonym: "regulation of 3',5' cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "regulation of 3',5'-cyclic-AMP phosphodiesterase activity" NARROW [] +synonym: "regulation of cAMP phosphodiesterase activity" NARROW [] +synonym: "regulation of cGMP phosphodiesterase activity" NARROW [GOC:tb] +synonym: "regulation of cyclic nucleotide phosphodiesterase activity" EXACT [GOC:tb] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity +relationship: regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0051343 +name: positive regulation of cyclic-nucleotide phosphodiesterase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate." [GOC:ai, GOC:tb] +synonym: "3',5' cyclic nucleotide phosphodiesterase activator" EXACT [] +synonym: "3',5'-cyclic-AMP phosphodiesterase activator" NARROW [] +synonym: "activation of cyclic nucleotide phosphodiesterase activity" NARROW [] +synonym: "cAMP phosphodiesterase activator" NARROW [] +synonym: "phosphodiesterase activator" RELATED [] +synonym: "positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity" NARROW [] +synonym: "positive regulation of cAMP phosphodiesterase activity" NARROW [] +synonym: "positive regulation of cGMP phosphodiesterase activity" NARROW [GOC:tb] +synonym: "positive regulation of cyclic nucleotide phosphodiesterase activity" EXACT [GOC:tb] +synonym: "stimulation of cyclic nucleotide phosphodiesterase activity" NARROW [] +synonym: "up regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "up-regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "upregulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +is_a: GO:0051342 ! regulation of cyclic-nucleotide phosphodiesterase activity +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity +relationship: positively_regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0051344 +name: negative regulation of cyclic-nucleotide phosphodiesterase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate." [GOC:ai, GOC:tb] +synonym: "3',5' cyclic nucleotide phosphodiesterase inhibitor" EXACT [] +synonym: "3',5'-cyclic-AMP phosphodiesterase inhibitor" NARROW [] +synonym: "cAMP phosphodiesterase inhibitor" NARROW [] +synonym: "down regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "down-regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "downregulation of cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "inhibition of cyclic nucleotide phosphodiesterase activity" NARROW [] +synonym: "negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity" EXACT [] +synonym: "negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity" NARROW [] +synonym: "negative regulation of cAMP phosphodiesterase activity" NARROW [] +synonym: "negative regulation of cGMP phosphodiesterase activity" NARROW [GOC:tb] +synonym: "negative regulation of cyclic nucleotide phosphodiesterase activity" EXACT [GOC:tb] +synonym: "phosphodiesterase inhibitor" RELATED [] +is_a: GO:0051342 ! regulation of cyclic-nucleotide phosphodiesterase activity +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity +relationship: negatively_regulates GO:0004112 ! cyclic-nucleotide phosphodiesterase activity + +[Term] +id: GO:0051345 +name: positive regulation of hydrolase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] +synonym: "activation of hydrolase activity" NARROW [] +synonym: "hydrolase activator" EXACT [] +synonym: "stimulation of hydrolase activity" NARROW [] +synonym: "up regulation of hydrolase activity" EXACT [] +synonym: "up-regulation of hydrolase activity" EXACT [] +synonym: "upregulation of hydrolase activity" EXACT [] +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016787 ! hydrolase activity +relationship: positively_regulates GO:0016787 ! hydrolase activity + +[Term] +id: GO:0051346 +name: negative regulation of hydrolase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] +synonym: "down regulation of hydrolase activity" EXACT [] +synonym: "down-regulation of hydrolase activity" EXACT [] +synonym: "downregulation of hydrolase activity" EXACT [] +synonym: "hydrolase inhibitor" EXACT [] +synonym: "inhibition of hydrolase activity" NARROW [] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016787 ! hydrolase activity +relationship: negatively_regulates GO:0016787 ! hydrolase activity + +[Term] +id: GO:0051347 +name: positive regulation of transferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] +comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. +subset: gocheck_do_not_manually_annotate +synonym: "activation of transferase activity" NARROW [] +synonym: "stimulation of transferase activity" NARROW [] +synonym: "transferase activator" EXACT [] +synonym: "up regulation of transferase activity" EXACT [] +synonym: "up-regulation of transferase activity" EXACT [] +synonym: "upregulation of transferase activity" EXACT [] +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016740 ! transferase activity +relationship: positively_regulates GO:0016740 ! transferase activity + +[Term] +id: GO:0051348 +name: negative regulation of transferase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] +comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. +subset: gocheck_do_not_manually_annotate +synonym: "down regulation of transferase activity" EXACT [] +synonym: "down-regulation of transferase activity" EXACT [] +synonym: "downregulation of transferase activity" EXACT [] +synonym: "inhibition of transferase activity" NARROW [] +synonym: "transferase inhibitor" EXACT [] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016740 ! transferase activity +relationship: negatively_regulates GO:0016740 ! transferase activity + +[Term] +id: GO:0051349 +name: positive regulation of lyase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:ai] +synonym: "activation of lyase activity" NARROW [] +synonym: "lyase activator" EXACT [] +synonym: "stimulation of lyase activity" NARROW [] +synonym: "up regulation of lyase activity" EXACT [] +synonym: "up-regulation of lyase activity" EXACT [] +synonym: "upregulation of lyase activity" EXACT [] +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016829 ! lyase activity +relationship: positively_regulates GO:0016829 ! lyase activity + +[Term] +id: GO:0051350 +name: negative regulation of lyase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:ai] +synonym: "down regulation of lyase activity" EXACT [] +synonym: "down-regulation of lyase activity" EXACT [] +synonym: "downregulation of lyase activity" EXACT [] +synonym: "inhibition of lyase activity" NARROW [] +synonym: "lyase inhibitor" EXACT [] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016829 ! lyase activity +relationship: negatively_regulates GO:0016829 ! lyase activity + +[Term] +id: GO:0051351 +name: positive regulation of ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:ai] +synonym: "activation of ligase activity" NARROW [] +synonym: "ligase activator" EXACT [] +synonym: "stimulation of ligase activity" NARROW [] +synonym: "up regulation of ligase activity" EXACT [] +synonym: "up-regulation of ligase activity" EXACT [] +synonym: "upregulation of ligase activity" EXACT [] +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016874 ! ligase activity +relationship: positively_regulates GO:0016874 ! ligase activity + +[Term] +id: GO:0051352 +name: negative regulation of ligase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:ai] +synonym: "down regulation of ligase activity" EXACT [] +synonym: "down-regulation of ligase activity" EXACT [] +synonym: "downregulation of ligase activity" EXACT [] +synonym: "inhibition of ligase activity" NARROW [] +synonym: "ligase inhibitor" EXACT [] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016874 ! ligase activity +relationship: negatively_regulates GO:0016874 ! ligase activity + +[Term] +id: GO:0051353 +name: positive regulation of oxidoreductase activity +namespace: biological_process +alt_id: GO:0009391 +def: "Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered." [GOC:ai] +synonym: "activation of oxidoreductase activity" NARROW [] +synonym: "oxidoreductase activator" EXACT [] +synonym: "ribonucleotide reductase activating enzyme activity" NARROW [] +synonym: "stimulation of oxidoreductase activity" NARROW [] +synonym: "up regulation of oxidoreductase activity" EXACT [] +synonym: "up-regulation of oxidoreductase activity" EXACT [] +synonym: "upregulation of oxidoreductase activity" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016491 ! oxidoreductase activity +relationship: positively_regulates GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0051354 +name: negative regulation of oxidoreductase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered." [GOC:ai] +synonym: "down regulation of oxidoreductase activity" EXACT [] +synonym: "down-regulation of oxidoreductase activity" EXACT [] +synonym: "downregulation of oxidoreductase activity" EXACT [] +synonym: "inhibition of oxidoreductase activity" NARROW [] +synonym: "oxidoreductase inhibitor" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016491 ! oxidoreductase activity +relationship: negatively_regulates GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0051355 +name: proprioception involved in equilibrioception +namespace: biological_process +def: "The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity." [GOC:ai] +synonym: "equilibrioception by proprioception" EXACT [] +synonym: "perception of orientation with respect to gravity by proprioception" EXACT [] +synonym: "proprioception during equilibrioception" RELATED [GOC:dph, GOC:tb] +is_a: GO:0019230 ! proprioception +intersection_of: GO:0019230 ! proprioception +intersection_of: part_of GO:0050957 ! equilibrioception +relationship: part_of GO:0050957 ! equilibrioception + +[Term] +id: GO:0051356 +name: visual perception involved in equilibrioception +namespace: biological_process +def: "The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity." [GOC:ai] +synonym: "equilibrioception by visual perception" NARROW [] +synonym: "perception of orientation with respect to gravity by visual perception" EXACT [] +synonym: "visual perception during equilibrioception" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007601 ! visual perception +intersection_of: GO:0007601 ! visual perception +intersection_of: part_of GO:0050957 ! equilibrioception +relationship: part_of GO:0050957 ! equilibrioception + +[Term] +id: GO:0051357 +name: peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one +namespace: biological_process +def: "The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons." [PMID:10852900, PMID:11259412, PMID:15491166, RESID:AA0377] +comment: Note that this predicted modification is now thought not to exist. See the biological process term 'peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine ; GO:0051359'. +synonym: "biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine" EXACT [] +xref: RESID:AA0377 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018206 ! peptidyl-methionine modification +is_a: GO:0018212 ! peptidyl-tyrosine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051358 +name: peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine +namespace: biological_process +def: "The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus." [PMID:11682051, RESID:AA0378] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine" EXACT [] +xref: RESID:AA0378 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018200 ! peptidyl-glutamic acid modification +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051359 +name: peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine +namespace: biological_process +def: "The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor." [PDB:1UIS, PDB:1XQM, PMID:10852900, PMID:12185250, PMID:12909624, PMID:15542608, RESID:AA0379] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine" EXACT [] +xref: RESID:AA0379 +is_a: GO:0018149 ! peptide cross-linking +is_a: GO:0018201 ! peptidyl-glycine modification +is_a: GO:0018206 ! peptidyl-methionine modification +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051360 +name: peptide cross-linking via L-asparagine 5-imidazolinone glycine +namespace: biological_process +def: "The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons." [PMID:10504696, RESID:AA0380] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine" EXACT [] +xref: RESID:AA0380 +is_a: GO:0018196 ! peptidyl-asparagine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051361 +name: peptide cross-linking via L-lysine 5-imidazolinone glycine +namespace: biological_process +def: "The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons." [PMID:10504696, RESID:AA0381] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine" EXACT [] +xref: RESID:AA0381 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051362 +name: peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine +namespace: biological_process +def: "The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species." [PDB:1XAE, PMID:10504696, PMID:15628861, RESID:AA0382] +comment: See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'. +synonym: "biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine" EXACT [] +synonym: "biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine" EXACT [] +xref: RESID:AA0382 +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0018253 ! peptide cross-linking via 5-imidazolinone glycine +is_a: GO:0018298 ! protein-chromophore linkage + +[Term] +id: GO:0051363 +name: peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein +namespace: biological_process +def: "The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan." [PMID:8163519, PMID:9086265, RESID:AA0383] +comment: Note that this modification may be unique to the species Finegoldia (Peptostreptococcus) magnus. +xref: RESID:AA0383 +is_a: GO:0018104 ! peptidoglycan-protein cross-linking +is_a: GO:0018194 ! peptidyl-alanine modification + +[Term] +id: GO:0051364 +name: N-terminal peptidyl-proline N-formylation +namespace: biological_process +def: "The formylation of the N-terminal proline of proteins to form the derivative N-formylproline." [PMID:12051774, PMID:5464655, RESID:AA0384] +xref: RESID:AA0384 +is_a: GO:0018004 ! N-terminal protein formylation +is_a: GO:0018208 ! peptidyl-proline modification + +[Term] +id: GO:0051365 +name: cellular response to potassium ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions." [GOC:sm] +synonym: "cellular response to K+ ion deprivation" EXACT [] +synonym: "cellular response to K+ ion starvation" EXACT [] +synonym: "cellular response to potassium ion deprivation" EXACT [] +synonym: "cellular response to potassium starvation" EXACT [] +is_a: GO:0009267 ! cellular response to starvation + +[Term] +id: GO:0051366 +name: protein decanoylation +namespace: biological_process +def: "The modification of a protein amino acid by formation of an ester or amide with decanoic acid." [GOC:jsg] +synonym: "protein amino acid decanoylation" EXACT [GOC:bf] +is_a: GO:0006497 ! protein lipidation +is_a: GO:0043543 ! protein acylation + +[Term] +id: GO:0051367 +name: peptidyl-serine decanoylation +namespace: biological_process +def: "The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin." [GOC:jsg, PMID:12630926, RESID:AA0385] +xref: RESID:AA0385 +is_a: GO:0018209 ! peptidyl-serine modification +is_a: GO:0051366 ! protein decanoylation + +[Term] +id: GO:0051368 +name: peptidyl-threonine octanoylation +namespace: biological_process +def: "The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin." [GOC:jsg, PMID:11546772, RESID:AA0387] +xref: RESID:AA0386 +is_a: GO:0018190 ! protein octanoylation +is_a: GO:0018210 ! peptidyl-threonine modification + +[Term] +id: GO:0051369 +name: peptidyl-threonine decanoylation +namespace: biological_process +def: "The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin." [GOC:jsg, PMID:11546772, RESID:AA0387] +xref: RESID:AA0387 +is_a: GO:0018210 ! peptidyl-threonine modification +is_a: GO:0051366 ! protein decanoylation + +[Term] +id: GO:0051370 +name: obsolete ZASP binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain." [PMID:10427098, PMID:11699871] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "Z-band alternatively spliced PDZ-motif protein binding" EXACT [] +synonym: "ZASP binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0051371 +name: muscle alpha-actinin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc." [PMID:10984498, PMID:11699871, PMID:15014165] +synonym: "alpha-actinin 2 binding" NARROW [] +synonym: "alpha-actinin 3 binding" NARROW [] +is_a: GO:0051393 ! alpha-actinin binding + +[Term] +id: GO:0051373 +name: FATZ binding +namespace: molecular_function +alt_id: GO:0051374 +alt_id: GO:0051375 +alt_id: GO:0051376 +def: "Interacting selectively and non-covalently with a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components." [PMID:10984498, PMID:11699871] +synonym: "calsarcin 1 binding" EXACT [] +synonym: "calsarcin 2 binding" EXACT [] +synonym: "calsarcin 3 binding" EXACT [] +synonym: "calsarcin binding" EXACT [] +synonym: "FATZ 1 binding" EXACT [] +synonym: "FATZ 2 binding" EXACT [] +synonym: "FATZ 3 binding" EXACT [] +synonym: "filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle" EXACT [] +is_a: GO:0008092 ! cytoskeletal protein binding + +[Term] +id: GO:0051377 +name: mannose-ethanolamine phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor." [PMID:15632136] +synonym: "addition of ethanolamine phosphate to mannose of GPI precursor" EXACT [] +synonym: "ethanolamine phosphate transferase activity" BROAD [] +synonym: "EtN-P transferase activity" EXACT [] +synonym: "phosphoethanolamine transferase activity" BROAD [] +xref: Reactome:R-HSA-162798 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol" +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0051378 +name: serotonin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:ai] +synonym: "5-hydroxytryptamine binding" EXACT [] +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0043169 ! cation binding +is_a: GO:0043176 ! amine binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0051379 +name: epinephrine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:ai] +synonym: "adrenaline binding" EXACT [] +is_a: GO:1901338 ! catecholamine binding + +[Term] +id: GO:0051380 +name: norepinephrine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] +synonym: "noradrenaline binding" EXACT [] +is_a: GO:1901338 ! catecholamine binding + +[Term] +id: GO:0051381 +name: histamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0043169 ! cation binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0051382 +name: kinetochore assembly +namespace: biological_process +alt_id: GO:0000069 +def: "The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GOC:ai] +synonym: "centromere and kinetochore complex maturation" NARROW [] +synonym: "centromere/kinetochore complex maturation" NARROW [] +synonym: "chromosome-kinetochore attachment" NARROW [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "kinetochore formation" RELATED [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0051383 ! kinetochore organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0034508 ! centromere complex assembly + +[Term] +id: GO:0051383 +name: kinetochore organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] +synonym: "kinetochore organisation" EXACT [] +synonym: "kinetochore organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0051384 +name: response to glucocorticoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [GOC:ai, PMID:9884123] +synonym: "response to glucocorticoid stimulus" EXACT [GOC:dos] +is_a: GO:0031960 ! response to corticosteroid + +[Term] +id: GO:0051385 +name: response to mineralocorticoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance." [GOC:ai, PMID:9884123] +synonym: "response to mineralocorticoid stimulus" EXACT [GOC:dos] +is_a: GO:0031960 ! response to corticosteroid + +[Term] +id: GO:0051386 +name: regulation of neurotrophin TRK receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway." [GOC:ai] +synonym: "regulation of nerve growth factor receptor signaling pathway" RELATED [GOC:jc] +synonym: "regulation of nerve growth factor receptor signalling pathway" EXACT [] +synonym: "regulation of NGF receptor signaling pathway" EXACT [] +synonym: "regulation of NGF receptor signalling pathway" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway +relationship: regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway + +[Term] +id: GO:0051387 +name: negative regulation of neurotrophin TRK receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway." [GOC:ai] +synonym: "down regulation of nerve growth factor receptor signaling pathway" EXACT [] +synonym: "down-regulation of nerve growth factor receptor signaling pathway" EXACT [] +synonym: "downregulation of nerve growth factor receptor signaling pathway" EXACT [] +synonym: "inhibition of nerve growth factor receptor signaling pathway" NARROW [] +synonym: "negative regulation of nerve growth factor receptor signaling pathway" RELATED [GOC:jc] +synonym: "negative regulation of nerve growth factor receptor signalling pathway" EXACT [] +synonym: "negative regulation of NGF receptor signaling pathway" EXACT [] +synonym: "negative regulation of NGF receptor signalling pathway" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0051386 ! regulation of neurotrophin TRK receptor signaling pathway +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway +relationship: negatively_regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway + +[Term] +id: GO:0051388 +name: positive regulation of neurotrophin TRK receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway." [GOC:ai] +synonym: "activation of nerve growth factor receptor signaling pathway" NARROW [] +synonym: "positive regulation of nerve growth factor receptor signaling pathway" RELATED [GOC:jc] +synonym: "positive regulation of nerve growth factor receptor signalling pathway" EXACT [] +synonym: "positive regulation of NGF receptor signaling pathway" EXACT [] +synonym: "positive regulation of NGF receptor signalling pathway" EXACT [] +synonym: "stimulation of nerve growth factor receptor signaling pathway" NARROW [] +synonym: "up regulation of nerve growth factor receptor signaling pathway" EXACT [] +synonym: "up-regulation of nerve growth factor receptor signaling pathway" EXACT [] +synonym: "upregulation of nerve growth factor receptor signaling pathway" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0051386 ! regulation of neurotrophin TRK receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway +relationship: positively_regulates GO:0048011 ! neurotrophin TRK receptor signaling pathway + +[Term] +id: GO:0051389 +name: inactivation of MAPKK activity +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK)." [GOC:ai] +synonym: "inactivation of MAP kinase kinase activity" EXACT [] +synonym: "termination of MAP kinase kinase activity" EXACT [] +synonym: "termination of MAPKK activity" EXACT [] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:0043405 ! regulation of MAP kinase activity +is_a: GO:0043409 ! negative regulation of MAPK cascade +relationship: negatively_regulates GO:0004708 ! MAP kinase kinase activity + +[Term] +id: GO:0051390 +name: inactivation of MAPKKK activity +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK)." [GOC:ai] +synonym: "inactivation of MAP kinase kinase kinase activity" EXACT [] +synonym: "termination of MAP kinase kinase kinase activity" EXACT [] +synonym: "termination of MAPKKK activity" EXACT [] +is_a: GO:0043405 ! regulation of MAP kinase activity +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +relationship: negatively_regulates GO:0004709 ! MAP kinase kinase kinase activity + +[Term] +id: GO:0051391 +name: tRNA acetylation +namespace: biological_process +def: "The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ai] +is_a: GO:0006400 ! tRNA modification +is_a: GO:1990884 ! RNA acetylation + +[Term] +id: GO:0051392 +name: tRNA N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA." [PMID:15037780] +synonym: "tRNA cytidine N-acetyltransferase activity" EXACT [] +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0051393 +name: alpha-actinin binding +namespace: molecular_function +alt_id: GO:0051372 +def: "Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats." [PMID:10984498, PMID:11699871, PMID:15014165] +synonym: "alpha-actinin 1 binding" NARROW [] +synonym: "alpha-actinin 4 binding" NARROW [] +synonym: "nonmuscle alpha-actinin binding" NARROW [] +is_a: GO:0042805 ! actinin binding + +[Term] +id: GO:0051394 +name: regulation of nerve growth factor receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor." [GOC:ai] +synonym: "regulation of NGF receptor activity" EXACT [] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010465 ! nerve growth factor receptor activity +relationship: regulates GO:0010465 ! nerve growth factor receptor activity + +[Term] +id: GO:0051395 +name: negative regulation of nerve growth factor receptor activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor." [GOC:ai] +synonym: "down regulation of nerve growth factor receptor activity" EXACT [] +synonym: "down-regulation of nerve growth factor receptor activity" EXACT [] +synonym: "downregulation of nerve growth factor receptor activity" EXACT [] +synonym: "inhibition of nerve growth factor receptor activity" NARROW [] +synonym: "negative regulation of NGF receptor activity" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0051394 ! regulation of nerve growth factor receptor activity +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010465 ! nerve growth factor receptor activity +relationship: negatively_regulates GO:0010465 ! nerve growth factor receptor activity + +[Term] +id: GO:0051396 +name: positive regulation of nerve growth factor receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor." [GOC:ai] +synonym: "activation of nerve growth factor receptor activity" NARROW [] +synonym: "positive regulation of NGF receptor activity" EXACT [] +synonym: "stimulation of nerve growth factor receptor activity" NARROW [] +synonym: "up regulation of nerve growth factor receptor activity" EXACT [] +synonym: "up-regulation of nerve growth factor receptor activity" EXACT [] +synonym: "upregulation of nerve growth factor receptor activity" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0051394 ! regulation of nerve growth factor receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010465 ! nerve growth factor receptor activity +relationship: positively_regulates GO:0010465 ! nerve growth factor receptor activity + +[Term] +id: GO:0051397 +name: obsolete N-terminal basic amino acid aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai] +comment: This term was made obsolete because it represents a gene product. +synonym: "N-terminal basic amino acid aminopeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0051398 +name: obsolete N-terminal lysine aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai, PMID:12799365] +comment: This term was made obsolete because it represents a gene product. +synonym: "lysine aminopeptidase activity" BROAD [] +synonym: "lysyl aminopeptidase activity" BROAD [] +synonym: "N-terminal lysine aminopeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0051399 +name: obsolete N-terminal arginine aminopeptidase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai, PMID:12799365] +comment: This term was made obsolete because it represents a gene product. +synonym: "arginine aminopeptidase activity" BROAD [] +synonym: "argininyl aminopeptidase activity" BROAD [] +synonym: "N-terminal arginine aminopeptidase activity" EXACT [] +is_obsolete: true +replaced_by: GO:0004177 + +[Term] +id: GO:0051400 +name: BH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409] +subset: goslim_chembl +synonym: "Bcl-2 homology domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0051401 +name: CH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins." [PMID:11911887, Prosite:PDOC50021] +synonym: "calponin homology domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0051402 +name: neuron apoptotic process +namespace: biological_process +def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis, MeSH:A.08.663] +synonym: "apoptosis of neuronal cells" EXACT [] +synonym: "apoptosis of neurons" EXACT [] +synonym: "neuron apoptosis" NARROW [] +synonym: "neuron programmed cell death by apoptosis" EXACT [] +synonym: "neuronal cell apoptosis" EXACT [] +synonym: "neuronal cell programmed cell death by apoptosis" EXACT [] +synonym: "programmed cell death of neuronal cells by apoptosis" EXACT [] +synonym: "programmed cell death of neurons by apoptosis" EXACT [] +synonym: "programmed cell death, neuronal cells" EXACT [] +synonym: "programmed cell death, neurons" EXACT [] +is_a: GO:0006915 ! apoptotic process +is_a: GO:0070997 ! neuron death + +[Term] +id: GO:0051403 +name: stress-activated MAPK cascade +namespace: biological_process +def: "A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase." [GOC:ai, PMID:15936270] +synonym: "MAPK11 cascade" NARROW [GOC:add] +synonym: "MAPK12 cascade" NARROW [GOC:add] +synonym: "MAPK13 cascade" NARROW [GOC:add] +synonym: "MAPK14 cascade" NARROW [GOC:add] +synonym: "p38 cascade" NARROW [GOC:add] +synonym: "p38 MAPK signaling" NARROW [] +synonym: "p38 MAPK signalling" NARROW [] +synonym: "SAPK cascade" BROAD [GOC:add] +synonym: "stress-activated MAPK signaling pathway" EXACT [] +synonym: "stress-activated MAPK signalling pathway" EXACT [] +synonym: "stress-activated MAPKKK cascade" EXACT [] +synonym: "stress-activated MAPKKK signaling pathway" EXACT [] +synonym: "stress-activated MAPKKK signalling pathway" EXACT [] +is_a: GO:0000165 ! MAPK cascade +is_a: GO:0031098 ! stress-activated protein kinase signaling cascade + +[Term] +id: GO:0051404 +name: obsolete clostripain activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds." [EC:3.4.22.8] +comment: This term was made obsolete because it represents a gene product. +synonym: "alpha-clostridipain" RELATED [EC:3.4.22.8] +synonym: "clostridiopeptidase B activity" EXACT [] +synonym: "Clostridium histolyticum proteinase B" RELATED [EC:3.4.22.8] +synonym: "clostripain activity" EXACT [] +xref: EC:3.4.22.8 +is_obsolete: true +replaced_by: GO:0004197 + +[Term] +id: GO:0051405 +name: obsolete microbial collagenase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds." [EC:3.4.24.3] +comment: This term was made obsolete because it represents a gene product. +synonym: "Achromobacter iophagus collagenase" RELATED [EC:3.4.24.3] +synonym: "aspergillopeptidase C" RELATED [EC:3.4.24.3] +synonym: "azocollase activity" EXACT [EC:3.4.24.3] +synonym: "clostridiopeptidase A activity" EXACT [] +synonym: "clostridiopeptidase I" RELATED [EC:3.4.24.3] +synonym: "clostridiopeptidase II" RELATED [EC:3.4.24.3] +synonym: "Clostridium histolyticum collagenase activity" NARROW [EC:3.4.24.3] +synonym: "Clostridium histolyticum proteinase A" RELATED [EC:3.4.24.3] +synonym: "collagen peptidase activity" EXACT [EC:3.4.24.3] +synonym: "collagen protease activity" EXACT [EC:3.4.24.3] +synonym: "collagenase 1 activity" EXACT [] +synonym: "collagenase A activity" EXACT [] +synonym: "collagenase I activity" EXACT [EC:3.4.24.3] +synonym: "collagenase MMP-1" RELATED [EC:3.4.24.3] +synonym: "kollaza" RELATED [EC:3.4.24.3] +synonym: "matirx metalloproteinase-18" RELATED [EC:3.4.24.3] +synonym: "matrix metalloproteinase-1" RELATED [EC:3.4.24.3] +synonym: "matrix metalloproteinase-8" RELATED [EC:3.4.24.3] +synonym: "metallocollagenase activity" EXACT [EC:3.4.24.3] +synonym: "metalloproteinase-1" RELATED [EC:3.4.24.3] +synonym: "microbial collagenase activity" EXACT [] +synonym: "nucleolysin" RELATED [EC:3.4.24.3] +synonym: "soycollagestin" RELATED [EC:3.4.24.3] +xref: EC:3.4.24.3 +is_obsolete: true +replaced_by: GO:0004252 + +[Term] +id: GO:0051407 +name: glycerone phosphate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out)." [GOC:ai] +synonym: "dihydroxyacetone-phosphate:inorganic phosphate antiporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015315 ! organophosphate:inorganic phosphate antiporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity + +[Term] +id: GO:0051408 +name: glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out)." [GOC:ai] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0009670 ! triose-phosphate:phosphate antiporter activity +is_a: GO:0015301 ! anion:anion antiporter activity + +[Term] +id: GO:0051409 +name: response to nitrosative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [PMID:15925705] +is_a: GO:0006950 ! response to stress + +[Term] +id: GO:0051410 +name: detoxification of nitrogen compound +namespace: biological_process +def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai] +synonym: "detoxification of nitrogenous compound" EXACT [] +synonym: "nitric oxide (NO) detoxification" NARROW [] +is_a: GO:0098754 ! detoxification +relationship: part_of GO:1901698 ! response to nitrogen compound + +[Term] +id: GO:0051411 +name: obsolete ALP binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band." [PMID:11699871] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "actinin-associated LIM protein binding" EXACT [] +synonym: "ALP binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0051412 +name: response to corticosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses." [PMID:15240347] +synonym: "response to corticosterone stimulus" EXACT [GOC:dos] +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0051385 ! response to mineralocorticoid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0051413 +name: response to cortisone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues." [ISBN:0721662544, PMID:11276391] +synonym: "response to cortisone stimulus" EXACT [GOC:dos] +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0051414 +name: response to cortisol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions." [ISBN:0721662544, PMID:11276391] +synonym: "response to cortisol stimulus" EXACT [GOC:dos] +synonym: "response to hydrocortisone stimulus" EXACT [] +is_a: GO:0042493 ! response to drug +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0051415 +name: microtubule nucleation by interphase microtubule organizing center +namespace: biological_process +def: "The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation." [GOC:ai] +synonym: "IMTOC-mediated microtubule nucleation during interphase" EXACT [] +synonym: "interphase microtubule nucleation by interphase microtubule organising centre" EXACT [] +synonym: "interphase microtubule nucleation by interphase microtubule organizing center" EXACT [] +synonym: "interphase microtubule organizing center-mediated microtubule nucleation during interphase" EXACT [] +synonym: "microtubule nucleation during interphase by IMTOC" EXACT [] +synonym: "microtubule nucleation during interphase by interphase microtubule organizing center" EXACT [] +is_a: GO:0051418 ! microtubule nucleation by microtubule organizing center + +[Term] +id: GO:0051416 +name: obsolete myotilin binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C." [PMID:11699871, PMID:15752755] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "myotilin binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0051417 +name: microtubule nucleation by spindle pole body +namespace: biological_process +def: "The 'de novo' formation of a microtubule, mediated by the spindle pole body." [GOC:ai] +synonym: "microtubule nucleation by SPB" EXACT [] +synonym: "SPB-mediated microtubule nucleation" EXACT [] +synonym: "spindle pole body-mediated microtubule nucleation" EXACT [] +is_a: GO:0051418 ! microtubule nucleation by microtubule organizing center + +[Term] +id: GO:0051418 +name: microtubule nucleation by microtubule organizing center +namespace: biological_process +def: "The 'de novo' formation of a microtubule, mediated by the microtubule organizing center." [GOC:ai] +synonym: "microtubule nucleation by microtubule organising centre" EXACT [] +synonym: "microtubule nucleation by MTOC" EXACT [] +synonym: "microtubule organizing center-mediated microtubule nucleation" EXACT [] +synonym: "MTOC-mediated microtubule nucleation" EXACT [] +is_a: GO:0007020 ! microtubule nucleation + +[Term] +id: GO:0051419 +name: obsolete nebulin binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone." [PMID:11699871] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "nebulin binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0051420 +name: obsolete nebulette binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin." [PMID:11699871] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "nebulette binding" EXACT [] +is_obsolete: true +replaced_by: GO:0008092 + +[Term] +id: GO:0051421 +name: regulation of endo-1,4-beta-xylanase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans." [EC:3.2.1.8, GOC:ai] +synonym: "endo-1,4-beta-xylanase regulator" RELATED [] +synonym: "xylanase regulator" RELATED [] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031176 ! endo-1,4-beta-xylanase activity +relationship: regulates GO:0031176 ! endo-1,4-beta-xylanase activity + +[Term] +id: GO:0051422 +name: negative regulation of endo-1,4-beta-xylanase activity +namespace: biological_process +def: "Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans." [EC:3.2.1.8, GOC:ai] +synonym: "down regulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "down-regulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "downregulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "endo-1,4-beta-xylanase inhibitor" RELATED [] +synonym: "inhibition of endo-1,4-beta-xylanase activity" NARROW [] +synonym: "xylanase inhibitor" RELATED [] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0051421 ! regulation of endo-1,4-beta-xylanase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031176 ! endo-1,4-beta-xylanase activity +relationship: negatively_regulates GO:0031176 ! endo-1,4-beta-xylanase activity + +[Term] +id: GO:0051423 +name: positive regulation of endo-1,4-beta-xylanase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans." [EC:3.2.1.8, GOC:ai] +synonym: "activation of endo-1,4-beta-xylanase activity" NARROW [] +synonym: "endo-1,4-beta-xylanase activator" RELATED [] +synonym: "stimulation of endo-1,4-beta-xylanase activity" NARROW [] +synonym: "up regulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "up-regulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "upregulation of endo-1,4-beta-xylanase activity" EXACT [] +synonym: "xylanase activator" RELATED [] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0051421 ! regulation of endo-1,4-beta-xylanase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031176 ! endo-1,4-beta-xylanase activity +relationship: positively_regulates GO:0031176 ! endo-1,4-beta-xylanase activity + +[Term] +id: GO:0051424 +name: corticotropin-releasing hormone binding +namespace: molecular_function +alt_id: GO:0017047 +def: "Interacting selectively and non-covalently with corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland." [PMID:7556876] +synonym: "corticoliberin binding" EXACT [] +synonym: "corticotropin-releasing factor binding" EXACT [] +synonym: "CRF binding" EXACT [GOC:bf] +synonym: "CRH binding" EXACT [] +is_a: GO:0017046 ! peptide hormone binding +is_a: GO:0042165 ! neurotransmitter binding + +[Term] +id: GO:0051425 +name: PTB domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a phosphotyrosine-binding (PTB) domain of a protein." [Pfam:PF02174.5, PMID:15924411] +synonym: "phosphotyrosine-interacting domain binding" EXACT [] +synonym: "PID binding" BROAD [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0051427 +name: hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor for hormones." [GOC:ai] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0051428 +name: peptide hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor for peptide hormones." [GOC:ai] +subset: goslim_chembl +synonym: "polypeptide hormone receptor binding" EXACT [] +is_a: GO:0051427 ! hormone receptor binding + +[Term] +id: GO:0051429 +name: corticotropin-releasing hormone receptor binding +namespace: molecular_function +alt_id: GO:0031742 +def: "Interacting selectively and non-covalently with a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland." [GOC:ai] +synonym: "corticotropin releasing factor receptor binding" EXACT [] +synonym: "corticotropin releasing factor receptor ligand" NARROW [] +synonym: "corticotropin-releasing factor receptor binding" EXACT [GOC:bf] +synonym: "CRF receptor binding" EXACT [GOC:bf] +synonym: "CRH receptor binding" EXACT [GOC:bf] +synonym: "CRHR binding" EXACT [GOC:bf] +is_a: GO:0051428 ! peptide hormone receptor binding +is_a: GO:0071855 ! neuropeptide receptor binding + +[Term] +id: GO:0051430 +name: corticotropin-releasing hormone receptor 1 binding +namespace: molecular_function +alt_id: GO:0031743 +def: "Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system." [PMID:15134857] +synonym: "CRHR1 binding" EXACT [] +synonym: "type 1 corticotropin releasing factor receptor binding" EXACT [] +synonym: "type 1 corticotropin releasing factor receptor ligand" NARROW [] +synonym: "type 1 corticotropin-releasing factor receptor binding" EXACT [GOC:bf] +is_a: GO:0051429 ! corticotropin-releasing hormone receptor binding + +[Term] +id: GO:0051431 +name: corticotropin-releasing hormone receptor 2 binding +namespace: molecular_function +alt_id: GO:0031744 +def: "Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery." [PMID:15134857] +synonym: "CRHR2 binding" EXACT [] +synonym: "type 2 corticotropin releasing factor receptor binding" EXACT [] +synonym: "type 2 corticotropin releasing factor receptor ligand" NARROW [] +synonym: "type 2 corticotropin-releasing factor receptor binding" EXACT [GOC:bf] +is_a: GO:0051429 ! corticotropin-releasing hormone receptor binding + +[Term] +id: GO:0051432 +name: BH1 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the BH1 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01080] +is_a: GO:0051400 ! BH domain binding + +[Term] +id: GO:0051433 +name: BH2 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01258] +is_a: GO:0051400 ! BH domain binding + +[Term] +id: GO:0051434 +name: BH3 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01259] +subset: goslim_chembl +is_a: GO:0051400 ! BH domain binding +is_a: GO:0070513 ! death domain binding + +[Term] +id: GO:0051435 +name: BH4 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein." [InterPro:IPR003093, PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01260, Prosite:PS50063] +is_a: GO:0051400 ! BH domain binding + +[Term] +id: GO:0051436 +name: obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle." [GOC:ai, GOC:tb] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "anaphase promoting complex inhibition during mitotic cell cycle" NARROW [] +synonym: "anaphase-promoting complex inhibition during mitotic cell cycle" NARROW [] +synonym: "APC inhibition during mitotic cell cycle" NARROW [] +synonym: "down regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +synonym: "down-regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +synonym: "downregulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +synonym: "inhibition of ubiquitin ligase activity during mitotic cell cycle" NARROW [] +synonym: "mitotic anaphase promoting complex inhibition" NARROW [] +synonym: "mitotic anaphase promoting complex inhibitor" NARROW [] +synonym: "mitotic anaphase-promoting complex inhibition" NARROW [] +synonym: "mitotic anaphase-promoting complex inhibitor" NARROW [] +synonym: "mitotic APC inhibition" NARROW [] +synonym: "mitotic APC inhibitor" NARROW [] +synonym: "mitotic SCF complex inhibitor" NARROW [] +synonym: "mitotic ubiquitin ligase inhibitor" NARROW [] +synonym: "negative regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [GOC:tb] +synonym: "negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15196 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051437 +name: obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition." [GOC:ai, GOC:tb] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "activation of ubiquitin ligase activity during mitotic cell cycle" NARROW [] +synonym: "mitotic SCF complex activator" NARROW [] +synonym: "mitotic ubiquitin ligase activator" NARROW [] +synonym: "positive regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [GOC:tb] +synonym: "positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "stimulation of ubiquitin ligase activity during mitotic cell cycle" NARROW [] +synonym: "up regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +synonym: "up-regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +synonym: "upregulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15196 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051438 +name: regulation of ubiquitin-protein transferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ubiquitin transferase activity." [GOC:ai, GOC:tb] +synonym: "anaphase-promoting complex regulator" NARROW [] +synonym: "APC regulator" NARROW [] +synonym: "regulation of ubiquitin transferase activity" EXACT [GOC:tb] +synonym: "SCF complex regulator" NARROW [] +synonym: "ubiquitin transferase regulator" RELATED [] +synonym: "ubiquitin-protein transferase regulator" RELATED [] +is_a: GO:0031396 ! regulation of protein ubiquitination +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004842 ! ubiquitin-protein transferase activity +relationship: regulates GO:0004842 ! ubiquitin-protein transferase activity + +[Term] +id: GO:0051439 +name: obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle." [GOC:ai] +comment: false +synonym: "mitotic anaphase-promoting complex regulator" NARROW [] +synonym: "mitotic APC regulator" NARROW [] +synonym: "mitotic SCF complex regulator" NARROW [] +synonym: "mitotic ubiquitin ligase regulator" RELATED [] +synonym: "mitotic ubiquitin-protein ligase regulator" RELATED [] +synonym: "regulation of ubiquitin ligase activity during mitotic cell cycle" RELATED [GOC:tb] +synonym: "regulation of ubiquitin-protein ligase activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +is_obsolete: true + +[Term] +id: GO:0051440 +name: obsolete regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle +namespace: biological_process +def: "OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai, GOC:tb] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "meiotic anaphase-promoting complex regulator" NARROW [] +synonym: "meiotic APC regulator" NARROW [] +synonym: "meiotic SCF complex regulator" NARROW [] +synonym: "meiotic ubiquitin ligase regulator" RELATED [] +synonym: "meiotic ubiquitin-protein ligase regulator" RELATED [] +synonym: "regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [GOC:tb] +synonym: "regulation of ubiquitin-protein ligase activity during meiotic cell cycle" RELATED [GOC:dph, GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15196 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051441 +name: obsolete positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle +namespace: biological_process +alt_id: GO:0051487 +def: "OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:mah, GOC:tb, PMID:10871297] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "activation of anaphase-promoting complex activity during meiotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "activation of anaphase-promoting complex activity involved in meiotic cell cycle" NARROW [] +synonym: "activation of ubiquitin ligase activity during meiotic cell cycle" NARROW [] +synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle" RELATED [] +synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle" RELATED [] +synonym: "activation of ubiquitin ligase activity of APC during meiotic cell cycle" RELATED [] +synonym: "anaphase promoting complex activation during meiotic cell cycle" RELATED [] +synonym: "anaphase-promoting complex activation during meiotic cell cycle" RELATED [] +synonym: "APC activation during meiotic cell cycle" RELATED [] +synonym: "meiotic anaphase promoting complex activation" RELATED [] +synonym: "meiotic anaphase promoting complex activator" NARROW [] +synonym: "meiotic anaphase-promoting complex activator" NARROW [] +synonym: "meiotic APC activation" EXACT [] +synonym: "meiotic APC activator" NARROW [] +synonym: "meiotic SCF complex activator" NARROW [] +synonym: "meiotic ubiquitin ligase activator" NARROW [] +synonym: "positive regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [GOC:tb] +synonym: "positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "stimulation of ubiquitin ligase activity during meiotic cell cycle" NARROW [] +synonym: "up regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +synonym: "up-regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +synonym: "upregulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15196 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051442 +name: obsolete negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai, GOC:tb] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +synonym: "anaphase promoting complex inhibition during meiotic cell cycle" NARROW [] +synonym: "anaphase-promoting complex inhibition during meiotic cell cycle" NARROW [] +synonym: "APC inhibition during meiotic cell cycle" NARROW [] +synonym: "down regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +synonym: "down-regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +synonym: "downregulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [] +synonym: "inhibition of ubiquitin ligase activity during meiotic cell cycle" NARROW [] +synonym: "meiotic anaphase promoting complex inhibition" NARROW [] +synonym: "meiotic anaphase promoting complex inhibitor" NARROW [] +synonym: "meiotic anaphase-promoting complex inhibition" NARROW [] +synonym: "meiotic anaphase-promoting complex inhibitor" NARROW [] +synonym: "meiotic APC inhibition" NARROW [] +synonym: "meiotic APC inhibitor" NARROW [] +synonym: "meiotic SCF complex inhibitor" NARROW [] +synonym: "meiotic ubiquitin ligase inhibitor" NARROW [] +synonym: "negative regulation of ubiquitin ligase activity during meiotic cell cycle" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15196 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051443 +name: positive regulation of ubiquitin-protein transferase activity +namespace: biological_process +def: "Any process that activates, maintains or increases the rate of ubiquitin transferase activity." [GOC:ai, GOC:tb] +synonym: "activation of ubiquitin transferase activity" NARROW [] +synonym: "anaphase promoting complex activator" NARROW [] +synonym: "anaphase-promoting complex activator" NARROW [] +synonym: "APC activation" NARROW [] +synonym: "APC activator" NARROW [] +synonym: "positive regulation of ubiquitin transferase activity" EXACT [GOC:tb] +synonym: "SCF complex activator" NARROW [] +synonym: "stimulation of ubiquitin transferase activity" NARROW [] +synonym: "ubiquitin transferase activator" NARROW [] +synonym: "up regulation of ubiquitin ligase activity" RELATED [] +synonym: "up-regulation of ubiquitin transferase activity" EXACT [] +synonym: "upregulation of ubiquitin transferase activity" EXACT [] +is_a: GO:0031398 ! positive regulation of protein ubiquitination +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004842 ! ubiquitin-protein transferase activity +relationship: positively_regulates GO:0004842 ! ubiquitin-protein transferase activity + +[Term] +id: GO:0051444 +name: negative regulation of ubiquitin-protein transferase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity." [GOC:ai, GOC:tb] +synonym: "anaphase promoting complex inhibition" NARROW [] +synonym: "anaphase promoting complex inhibitor" NARROW [] +synonym: "anaphase-promoting complex inhibition" NARROW [] +synonym: "anaphase-promoting complex inhibitor" NARROW [] +synonym: "APC inhibition" NARROW [] +synonym: "APC inhibitor" NARROW [] +synonym: "down regulation of ubiquitin transferase activity" EXACT [] +synonym: "down-regulation of ubiquitin transferase activity" EXACT [] +synonym: "downregulation of ubiquitin transferase activity" EXACT [] +synonym: "inhibition of ubiquitin transferase activity" NARROW [] +synonym: "negative regulation of ubiquitin transferase activity" EXACT [GOC:tb] +synonym: "SCF complex inhibitor" NARROW [] +synonym: "ubiquitin transferase inhibitor" NARROW [] +is_a: GO:0031397 ! negative regulation of protein ubiquitination +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004842 ! ubiquitin-protein transferase activity +relationship: negatively_regulates GO:0004842 ! ubiquitin-protein transferase activity + +[Term] +id: GO:0051445 +name: regulation of meiotic cell cycle +namespace: biological_process +def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] +synonym: "meiotic cell cycle modulation" EXACT [] +synonym: "meiotic cell cycle regulation" EXACT [] +synonym: "meiotic cell cycle regulator" RELATED [] +synonym: "modulation of meiotic cell cycle progression" EXACT [] +synonym: "regulation of meiotic cell cycle progression" EXACT [] +synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051726 ! regulation of cell cycle +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051321 ! meiotic cell cycle +relationship: regulates GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051446 +name: positive regulation of meiotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] +synonym: "activation of progression through meiotic cell cycle" NARROW [] +synonym: "positive regulation of meiotic cell cycle progression" EXACT [] +synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of progression through meiotic cell cycle" NARROW [] +synonym: "up regulation of progression through meiotic cell cycle" EXACT [] +synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] +synonym: "upregulation of progression through meiotic cell cycle" EXACT [] +is_a: GO:0045787 ! positive regulation of cell cycle +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051321 ! meiotic cell cycle +relationship: positively_regulates GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051447 +name: negative regulation of meiotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] +synonym: "down regulation of progression through meiotic cell cycle" EXACT [] +synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] +synonym: "downregulation of progression through meiotic cell cycle" EXACT [] +synonym: "inhibition of progression through meiotic cell cycle" NARROW [] +synonym: "negative regulation of meiotic cell cycle progression" EXACT [] +synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] +is_a: GO:0045786 ! negative regulation of cell cycle +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051321 ! meiotic cell cycle +relationship: negatively_regulates GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0051448 +name: gonadotropin-releasing hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus." [GOC:pr, PMID:1984190] +synonym: "GnRH binding" EXACT [] +synonym: "gonadotrophin releasing hormone binding" EXACT [] +is_a: GO:0017046 ! peptide hormone binding + +[Term] +id: GO:0051449 +name: thyrotropin-releasing hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system." [GOC:ai] +synonym: "thyrotropin releasing hormone binding" EXACT [] +is_a: GO:0017046 ! peptide hormone binding + +[Term] +id: GO:0051450 +name: myoblast proliferation +namespace: biological_process +def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0051451 +name: myoblast migration +namespace: biological_process +def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] +is_a: GO:0014812 ! muscle cell migration + +[Term] +id: GO:0051452 +name: intracellular pH reduction +namespace: biological_process +def: "Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion." [GOC:ai] +synonym: "cell pH reduction" EXACT [] +synonym: "cellular acidification" EXACT [] +synonym: "intracellular acidification" RELATED [] +synonym: "reduction of cellular pH" EXACT [] +synonym: "reduction of pH in cell" EXACT [] +is_a: GO:0045851 ! pH reduction +is_a: GO:0051453 ! regulation of intracellular pH + +[Term] +id: GO:0051453 +name: regulation of intracellular pH +namespace: biological_process +def: "Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion." [GOC:ai, GOC:dph, GOC:tb] +synonym: "cell pH regulation" EXACT [] +synonym: "cellular pH regulation" EXACT [] +synonym: "pH regulation in cell" EXACT [] +synonym: "regulation of cell pH" EXACT [] +is_a: GO:0030641 ! regulation of cellular pH + +[Term] +id: GO:0051454 +name: intracellular pH elevation +namespace: biological_process +def: "Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion." [GOC:ai] +synonym: "cell pH elevation" EXACT [] +synonym: "cellular alkalinization" EXACT [] +synonym: "elevation of cellular pH" EXACT [] +synonym: "intracellular alkalinization" EXACT [] +synonym: "pH elevation in cell" EXACT [] +is_a: GO:0045852 ! pH elevation +is_a: GO:0051453 ! regulation of intracellular pH + +[Term] +id: GO:0051455 +name: monopolar spindle attachment to meiosis I kinetochore +namespace: biological_process +def: "The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs." [GOC:ai, GOC:clt, GOC:dph, GOC:tb] +comment: Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis. +synonym: "attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [] +synonym: "attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:dph, GOC:tb] +synonym: "monopolar attachment" EXACT [] +synonym: "sister kinetochore mono-orientation" EXACT [] +is_a: GO:0051316 ! attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation +intersection_of: GO:0008608 ! attachment of spindle microtubules to kinetochore +intersection_of: part_of GO:0045143 ! homologous chromosome segregation +relationship: part_of GO:0045143 ! homologous chromosome segregation + +[Term] +id: GO:0051456 +name: attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation +namespace: biological_process +def: "The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt, GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore during meiosis II" RELATED [GOC:dph, GOC:tb] +synonym: "attachment of spindle microtubules to kinetochore involved in meiosis II" RELATED [GOC:dph, GOC:tb] +synonym: "meiotic bipolar attachment" RELATED [GOC:vw] +is_a: GO:0051316 ! attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation +intersection_of: GO:0008608 ! attachment of spindle microtubules to kinetochore +intersection_of: part_of GO:0045144 ! meiotic sister chromatid segregation +relationship: part_of GO:0045144 ! meiotic sister chromatid segregation + +[Term] +id: GO:0051457 +name: maintenance of protein location in nucleus +namespace: biological_process +def: "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." [GOC:ai] +synonym: "maintenance of nuclear protein localization" EXACT [] +synonym: "maintenance of protein localization in nucleus" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of protein location in cell nucleus" EXACT [] +synonym: "nuclear protein retention" NARROW [] +synonym: "nuclear protein sequestering" NARROW [] +synonym: "nuclear protein sequestration" NARROW [] +synonym: "protein retention in nucleus" NARROW [] +synonym: "protein sequestration in nucleus" NARROW [] +synonym: "protein storage in nucleus" NARROW [] +synonym: "protein-nuclear retention" NARROW [] +synonym: "sequestration of protein in nucleus" NARROW [] +synonym: "storage of protein in nucleus" NARROW [] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005634 ! nucleus +relationship: occurs_in GO:0005634 ! nucleus +relationship: part_of GO:0034504 ! protein localization to nucleus + +[Term] +id: GO:0051458 +name: corticotropin secretion +namespace: biological_process +def: "The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus." [GOC:cjm, PMID:11027914] +synonym: "ACTH secretion" EXACT [] +synonym: "adrenocorticotropic hormone secretion" EXACT [] +synonym: "adrenocorticotropin secretion" RELATED [GOC:dph, GOC:tb] +synonym: "adrenotropic hormone secretion" EXACT [] +synonym: "adrenotropin secretion" EXACT [] +synonym: "corticotropic hormone secretion" EXACT [] +is_a: GO:0030072 ! peptide hormone secretion +is_a: GO:0060986 ! endocrine hormone secretion + +[Term] +id: GO:0051459 +name: regulation of corticotropin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell." [GOC:ai, GOC:dph] +synonym: "regulation of ACTH secretion" EXACT [] +synonym: "regulation of adrenocorticotropic hormone secretion" EXACT [GOC:dph] +synonym: "regulation of adrenocorticotropin secretion" EXACT [] +synonym: "regulation of adrenotropin hormone secretion" EXACT [] +synonym: "regulation of adrenotropin secretion" EXACT [] +synonym: "regulation of corticotropic hormone secretion" EXACT [] +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051458 ! corticotropin secretion +relationship: regulates GO:0051458 ! corticotropin secretion + +[Term] +id: GO:0051460 +name: negative regulation of corticotropin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell." [GOC:ai] +synonym: "down regulation of adrenocorticotropin secretion" EXACT [] +synonym: "down-regulation of adrenocorticotropin secretion" EXACT [] +synonym: "downregulation of adrenocorticotropin secretion" EXACT [] +synonym: "inhibition of adrenocorticotropin secretion" NARROW [] +synonym: "negative regulation of ACTH secretion" EXACT [] +synonym: "negative regulation of adrenocorticotropic hormone secretion" EXACT [] +synonym: "negative regulation of adrenocorticotropin secretion" EXACT [] +synonym: "negative regulation of adrenotropic hormone secretion" EXACT [] +synonym: "negative regulation of adrenotropin secretion" EXACT [] +synonym: "negative regulation of corticotropic hormone secretion" EXACT [] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0051459 ! regulation of corticotropin secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051458 ! corticotropin secretion +relationship: negatively_regulates GO:0051458 ! corticotropin secretion + +[Term] +id: GO:0051461 +name: positive regulation of corticotropin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell." [GOC:ai] +synonym: "activation of adrenocorticotropin secretion" NARROW [] +synonym: "positive regulation of ACTH secretion" EXACT [] +synonym: "positive regulation of adrenocorticotropic hormone secretion" EXACT [] +synonym: "positive regulation of adrenocorticotropin secretion" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of adrenotropic hormone secretion" EXACT [] +synonym: "positive regulation of adrenotropin secretion" EXACT [] +synonym: "positive regulation of corticotropic hormone secretion" EXACT [] +synonym: "stimulation of adrenocorticotropin secretion" NARROW [] +synonym: "up regulation of adrenocorticotropin secretion" EXACT [] +synonym: "up-regulation of adrenocorticotropin secretion" EXACT [] +synonym: "upregulation of adrenocorticotropin secretion" EXACT [] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0051459 ! regulation of corticotropin secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051458 ! corticotropin secretion +relationship: positively_regulates GO:0051458 ! corticotropin secretion + +[Term] +id: GO:0051462 +name: regulation of cortisol secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell." [GOC:ai] +is_a: GO:2000849 ! regulation of glucocorticoid secretion +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043400 ! cortisol secretion +relationship: regulates GO:0043400 ! cortisol secretion + +[Term] +id: GO:0051463 +name: negative regulation of cortisol secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell." [GOC:ai] +synonym: "down regulation of cortisol secretion" EXACT [] +synonym: "down-regulation of cortisol secretion" EXACT [] +synonym: "downregulation of cortisol secretion" EXACT [] +synonym: "inhibition of cortisol secretion" NARROW [] +is_a: GO:0051462 ! regulation of cortisol secretion +is_a: GO:2000850 ! negative regulation of glucocorticoid secretion +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043400 ! cortisol secretion +relationship: negatively_regulates GO:0043400 ! cortisol secretion + +[Term] +id: GO:0051464 +name: positive regulation of cortisol secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell." [GOC:ai] +synonym: "activation of cortisol secretion" NARROW [] +synonym: "stimulation of cortisol secretion" NARROW [] +synonym: "up regulation of cortisol secretion" EXACT [] +synonym: "up-regulation of cortisol secretion" EXACT [] +synonym: "upregulation of cortisol secretion" EXACT [] +is_a: GO:0051462 ! regulation of cortisol secretion +is_a: GO:2000851 ! positive regulation of glucocorticoid secretion +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043400 ! cortisol secretion +relationship: positively_regulates GO:0043400 ! cortisol secretion + +[Term] +id: GO:0051465 +name: negative regulation of corticotropin-releasing hormone secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell." [GOC:ai] +synonym: "down regulation of corticotropin-releasing hormone secretion" EXACT [] +synonym: "down-regulation of corticotropin-releasing hormone secretion" EXACT [] +synonym: "downregulation of corticotropin-releasing hormone secretion" EXACT [] +synonym: "inhibition of corticotropin-releasing hormone secretion" NARROW [] +synonym: "negative regulation of corticotropin-releasing factor secretion" EXACT [] +synonym: "negative regulation of CRF secretion" EXACT [] +synonym: "negative regulation of CRH secretion" EXACT [] +is_a: GO:0043397 ! regulation of corticotropin-releasing hormone secretion +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043396 ! corticotropin-releasing hormone secretion +relationship: negatively_regulates GO:0043396 ! corticotropin-releasing hormone secretion + +[Term] +id: GO:0051466 +name: positive regulation of corticotropin-releasing hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell." [GOC:ai] +synonym: "activation of corticotropin-releasing hormone secretion" NARROW [] +synonym: "positive regulation of corticotropin-releasing factor secretion" EXACT [] +synonym: "positive regulation of CRF secretion" EXACT [] +synonym: "positive regulation of CRH secretion" EXACT [] +synonym: "stimulation of corticotropin-releasing hormone secretion" NARROW [] +synonym: "up regulation of corticotropin-releasing hormone secretion" EXACT [] +synonym: "up-regulation of corticotropin-releasing hormone secretion" EXACT [] +synonym: "upregulation of corticotropin-releasing hormone secretion" EXACT [] +is_a: GO:0043397 ! regulation of corticotropin-releasing hormone secretion +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043396 ! corticotropin-releasing hormone secretion +relationship: positively_regulates GO:0043396 ! corticotropin-releasing hormone secretion + +[Term] +id: GO:0051467 +name: detection of steroid hormone stimulus +namespace: biological_process +def: "The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal." [GOC:ai] +is_a: GO:0009720 ! detection of hormone stimulus +is_a: GO:0048545 ! response to steroid hormone + +[Term] +id: GO:0051468 +name: detection of glucocorticoid hormone stimulus +namespace: biological_process +def: "The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [GOC:ai] +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0051467 ! detection of steroid hormone stimulus + +[Term] +id: GO:0051469 +name: vesicle fusion with vacuole +namespace: biological_process +alt_id: GO:0042146 +def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai] +synonym: "heterotypic vacuole fusion (non-autophagic)" RELATED [] +synonym: "heterotypic vacuole fusion, non-autophagic" RELATED [] +is_a: GO:0006906 ! vesicle fusion +is_a: GO:0097576 ! vacuole fusion + +[Term] +id: GO:0051470 +name: ectoine transport +namespace: biological_process +def: "The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria." [GOC:ai] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0051472 +name: glucosylglycerol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol." [GOC:ai] +synonym: "glucosylglycerol metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process +is_a: GO:0019400 ! alditol metabolic process + +[Term] +id: GO:0051473 +name: glucosylglycerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol." [GOC:ai] +synonym: "glucosylglycerol anabolism" EXACT [] +synonym: "glucosylglycerol biosynthesis" EXACT [] +synonym: "glucosylglycerol formation" EXACT [] +synonym: "glucosylglycerol synthesis" EXACT [] +is_a: GO:0019401 ! alditol biosynthetic process +is_a: GO:0051472 ! glucosylglycerol metabolic process + +[Term] +id: GO:0051474 +name: glucosylglycerol transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0015166 ! polyol transmembrane transporter activity +relationship: part_of GO:0051475 ! glucosylglycerol transport + +[Term] +id: GO:0051475 +name: glucosylglycerol transport +namespace: biological_process +def: "The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport + +[Term] +id: GO:0051476 +name: mannosylglycerate transport +namespace: biological_process +def: "The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:1901656 ! glycoside transport + +[Term] +id: GO:0051477 +name: mannosylglycerate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a mannosylglycerate from one side of a membrane to the other." [GOC:ai, PMID:15034926] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0051476 ! mannosylglycerate transport + +[Term] +id: GO:0051478 +name: mannosylglycerate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms." [GOC:ai, PMID:11562374] +synonym: "mannosylglycerate metabolism" EXACT [] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0051479 +name: mannosylglycerate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms." [GOC:ai] +synonym: "mannosylglycerate anabolism" EXACT [] +synonym: "mannosylglycerate biosynthesis" EXACT [] +synonym: "mannosylglycerate formation" EXACT [] +synonym: "mannosylglycerate synthesis" EXACT [] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0034637 ! cellular carbohydrate biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0051478 ! mannosylglycerate metabolic process + +[Term] +id: GO:0051480 +name: regulation of cytosolic calcium ion concentration +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings." [GOC:ai, GOC:mah, GOC:rph] +synonym: "calcium ion homeostasis in cytoplasm" BROAD [] +synonym: "calcium ion homeostasis in cytosol" EXACT [] +synonym: "cytoplasmic calcium ion concentration regulation" BROAD [] +synonym: "cytoplasmic calcium ion homeostasis" BROAD [] +synonym: "cytosolic calcium ion concentration regulation" EXACT [] +synonym: "regulation of calcium ion concentration in cytoplasm" BROAD [] +synonym: "regulation of calcium ion concentration in cytosol" EXACT [] +synonym: "regulation of cytoplasmic calcium ion concentration" BROAD [] +synonym: "regulation of cytosolic calcium ion concentration" EXACT [] +is_a: GO:0006874 ! cellular calcium ion homeostasis + +[Term] +id: GO:0051481 +name: negative regulation of cytosolic calcium ion concentration +namespace: biological_process +def: "Any process that decreases the concentration of calcium ions in the cytosol." [GOC:ai] +synonym: "cytoplasmic calcium ion concentration reduction" BROAD [] +synonym: "cytosolic calcium ion concentration reduction" EXACT [] +synonym: "reduction of calcium ion concentration in cytoplasm" BROAD [] +synonym: "reduction of calcium ion concentration in cytosol" EXACT [] +synonym: "reduction of cytoplasmic calcium ion concentration" BROAD [] +synonym: "reduction of cytosolic calcium ion concentration" EXACT [] +is_a: GO:0051480 ! regulation of cytosolic calcium ion concentration + +[Term] +id: GO:0051482 +name: positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol." [GOC:ai, GOC:signaling] +synonym: "elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] +synonym: "elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" RELATED [] +synonym: "elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] +synonym: "elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] +synonym: "elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" RELATED [] +synonym: "elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger" EXACT [GOC:signaling] +synonym: "elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway" EXACT [] +synonym: "positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway" EXACT [] +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +intersection_of: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +intersection_of: part_of GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +relationship: part_of GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway + +[Term] +id: GO:0051483 +name: terpenoid biosynthetic process, mevalonate-independent +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate." [GOC:ai] +synonym: "mevalonate-independent terpene biosynthesis" NARROW [] +synonym: "mevalonate-independent terpene biosynthetic process" NARROW [] +synonym: "mevalonate-independent terpenoid biosynthesis" EXACT [] +synonym: "mevalonate-independent terpenoid biosynthetic process" EXACT [] +synonym: "terpene biosynthesis, mevalonate-independent" NARROW [] +synonym: "terpene biosynthetic process, mevalonate-independent" NARROW [] +synonym: "terpenoid anabolism, mevalonate-independent" EXACT [] +synonym: "terpenoid formation, mevalonate-independent" EXACT [] +synonym: "terpenoid synthesis, mevalonate-independent" EXACT [] +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0051484 +name: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate." [GOC:ai] +synonym: "isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism" RELATED [] +synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process" RELATED [] +synonym: "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process" RELATED [GOC:dph, GOC:tb] +synonym: "isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis" RELATED [] +synonym: "isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation" RELATED [] +synonym: "isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis" RELATED [] +xref: MetaCyc:NONMEVIPP-PWY +is_a: GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +intersection_of: GO:0019288 ! isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway +intersection_of: part_of GO:0016114 ! terpenoid biosynthetic process +relationship: part_of GO:0051483 ! terpenoid biosynthetic process, mevalonate-independent + +[Term] +id: GO:0051485 +name: terpenoid biosynthetic process, mevalonate-dependent +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates." [GOC:ai] +synonym: "terpene biosynthesis, mevalonate-dependent" NARROW [] +synonym: "terpene biosynthetic process, mevalonate-dependent" NARROW [] +synonym: "terpenoid anabolism, mevalonate-dependent" EXACT [] +synonym: "terpenoid formation, mevalonate-dependent" EXACT [] +synonym: "terpenoid synthesis, mevalonate-dependent" EXACT [] +is_a: GO:0016114 ! terpenoid biosynthetic process + +[Term] +id: GO:0051486 +name: isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates." [GOC:ai] +synonym: "isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism" RELATED [] +synonym: "isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process" RELATED [GOC:dph, GOC:tb] +synonym: "isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis" RELATED [] +synonym: "isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation" RELATED [] +synonym: "isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis" RELATED [] +is_a: GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +intersection_of: GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +intersection_of: part_of GO:0016114 ! terpenoid biosynthetic process +relationship: part_of GO:0051485 ! terpenoid biosynthetic process, mevalonate-dependent + +[Term] +id: GO:0051489 +name: regulation of filopodium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai, GOC:dph, GOC:tb] +synonym: "regulation of filopodia biosynthesis" EXACT [] +synonym: "regulation of filopodia formation" EXACT [] +synonym: "regulation of filopodium formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046847 ! filopodium assembly +relationship: regulates GO:0046847 ! filopodium assembly + +[Term] +id: GO:0051490 +name: negative regulation of filopodium assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai] +synonym: "down regulation of filopodium formation" EXACT [] +synonym: "down-regulation of filopodium formation" EXACT [] +synonym: "downregulation of filopodium formation" EXACT [] +synonym: "inhibition of filopodium formation" NARROW [] +synonym: "negative regulation of filopodia biosynthesis" EXACT [] +synonym: "negative regulation of filopodia formation" EXACT [] +synonym: "negative regulation of filopodium formation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051489 ! regulation of filopodium assembly +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046847 ! filopodium assembly +relationship: negatively_regulates GO:0046847 ! filopodium assembly + +[Term] +id: GO:0051491 +name: positive regulation of filopodium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai, GOC:dph, GOC:tb] +synonym: "activation of filopodium formation" NARROW [] +synonym: "positive regulation of filopodia biosynthesis" EXACT [] +synonym: "positive regulation of filopodia formation" EXACT [] +synonym: "positive regulation of filopodium formation" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of filopodium formation" NARROW [] +synonym: "up regulation of filopodium formation" EXACT [] +synonym: "up-regulation of filopodium formation" EXACT [] +synonym: "upregulation of filopodium formation" EXACT [] +is_a: GO:0051489 ! regulation of filopodium assembly +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046847 ! filopodium assembly +relationship: positively_regulates GO:0046847 ! filopodium assembly + +[Term] +id: GO:0051492 +name: regulation of stress fiber assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] +synonym: "regulation of stress fibre biosynthesis" RELATED [] +synonym: "regulation of stress fibre formation" EXACT [] +is_a: GO:0032231 ! regulation of actin filament bundle assembly +is_a: GO:0110020 ! regulation of actomyosin structure organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043149 ! stress fiber assembly +relationship: regulates GO:0043149 ! stress fiber assembly + +[Term] +id: GO:0051493 +name: regulation of cytoskeleton organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] +synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah] +synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007010 ! cytoskeleton organization +relationship: regulates GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0051494 +name: negative regulation of cytoskeleton organization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] +synonym: "down regulation of cytoskeleton organization" EXACT [] +synonym: "down-regulation of cytoskeleton organization" EXACT [] +synonym: "downregulation of cytoskeleton organization" EXACT [] +synonym: "inhibition of cytoskeleton organization" NARROW [] +synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah] +synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0051493 ! regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007010 ! cytoskeleton organization +relationship: negatively_regulates GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0051495 +name: positive regulation of cytoskeleton organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] +synonym: "activation of cytoskeleton organization" NARROW [] +synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah] +synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] +synonym: "stimulation of cytoskeleton organization" NARROW [] +synonym: "up regulation of cytoskeleton organization" EXACT [] +synonym: "up-regulation of cytoskeleton organization" EXACT [] +synonym: "upregulation of cytoskeleton organization" EXACT [] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0051493 ! regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007010 ! cytoskeleton organization +relationship: positively_regulates GO:0007010 ! cytoskeleton organization + +[Term] +id: GO:0051496 +name: positive regulation of stress fiber assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] +synonym: "activation of stress fiber formation" NARROW [] +synonym: "positive regulation of stress fibre biosynthesis" RELATED [] +synonym: "positive regulation of stress fibre formation" RELATED [] +synonym: "stimulation of stress fiber formation" NARROW [] +synonym: "up regulation of stress fiber formation" RELATED [] +synonym: "up-regulation of stress fiber formation" EXACT [] +synonym: "upregulation of stress fiber formation" RELATED [] +is_a: GO:0032233 ! positive regulation of actin filament bundle assembly +is_a: GO:0051492 ! regulation of stress fiber assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043149 ! stress fiber assembly +relationship: positively_regulates GO:0043149 ! stress fiber assembly + +[Term] +id: GO:0051497 +name: negative regulation of stress fiber assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] +synonym: "down regulation of stress fiber formation" RELATED [] +synonym: "down-regulation of stress fiber formation" EXACT [] +synonym: "downregulation of stress fiber formation" RELATED [] +synonym: "inhibition of stress fiber formation" NARROW [] +synonym: "negative regulation of stress fibre biosynthesis" RELATED [] +synonym: "negative regulation of stress fibre formation" RELATED [] +is_a: GO:0032232 ! negative regulation of actin filament bundle assembly +is_a: GO:0051492 ! regulation of stress fiber assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043149 ! stress fiber assembly +relationship: negatively_regulates GO:0043149 ! stress fiber assembly + +[Term] +id: GO:0051498 +name: syn-copalyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate." [MetaCyc:RXN-8528] +synonym: "diterpene cyclase activity" BROAD [] +xref: EC:5.5.1.14 +xref: MetaCyc:RXN-8528 +xref: RHEA:25524 +is_a: GO:0016872 ! intramolecular lyase activity + +[Term] +id: GO:0051499 +name: D-aminoacyl-tRNA deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA." [PMID:14527667] +xref: EC:3.1.1.96 +xref: MetaCyc:RXN-15041 +is_a: GO:0002161 ! aminoacyl-tRNA editing activity + +[Term] +id: GO:0051500 +name: D-tyrosyl-tRNA(Tyr) deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA." [PMID:14527667] +is_a: GO:0051499 ! D-aminoacyl-tRNA deacylase activity + +[Term] +id: GO:0051501 +name: diterpene phytoalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units." [GOC:ai, ISBN:0721662544] +synonym: "diterpene phytoalexin metabolism" EXACT [] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0051502 +name: diterpene phytoalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses." [GOC:ai] +synonym: "diterpene phytoalexin anabolism" EXACT [] +synonym: "diterpene phytoalexin biosynthesis" EXACT [] +synonym: "diterpene phytoalexin formation" EXACT [] +synonym: "diterpene phytoalexin synthesis" EXACT [] +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:0051501 ! diterpene phytoalexin metabolic process +is_a: GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0051503 +name: adenine nucleotide transport +namespace: biological_process +def: "The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0015865 ! purine nucleotide transport + +[Term] +id: GO:0051504 +name: diterpene phytoalexin precursor biosynthetic process pathway +namespace: biological_process +def: "A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins." [MetaCyc:PWY-2981] +synonym: "diterpene phytoalexin precursor anabolism pathway" EXACT [] +synonym: "diterpene phytoalexin precursor formation pathway" EXACT [] +synonym: "diterpene phytoalexin precursor synthesis pathway" EXACT [] +xref: MetaCyc:PWY-2981 +is_a: GO:0046246 ! terpene biosynthetic process +relationship: part_of GO:0051502 ! diterpene phytoalexin biosynthetic process + +[Term] +id: GO:0051505 +name: cholesterol UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-cholesterol." [GOC:ai] +is_a: GO:0016906 ! sterol 3-beta-glucosyltransferase activity + +[Term] +id: GO:0051506 +name: ergosterol UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol." [GOC:ai, RHEA:61836] +xref: MetaCyc:RXN-16975) +xref: RHEA:61836 +is_a: GO:0016906 ! sterol 3-beta-glucosyltransferase activity + +[Term] +id: GO:0051507 +name: beta-sitosterol UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol." [GOC:ai, RHEA:61832] +xref: MetaCyc:RXN-12128 +xref: RHEA:61832 +is_a: GO:0016906 ! sterol 3-beta-glucosyltransferase activity + +[Term] +id: GO:0051508 +name: stigmasterol UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol." [GOC:ai, RHEA:61828] +xref: MetaCyc:RXN-12126 +xref: RHEA:61828 +is_a: GO:0016906 ! sterol 3-beta-glucosyltransferase activity + +[Term] +id: GO:0051509 +name: tomatidine UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine." [GOC:ai] +is_a: GO:0016906 ! sterol 3-beta-glucosyltransferase activity + +[Term] +id: GO:0051510 +name: regulation of unidimensional cell growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] +synonym: "regulation of cell elongation" NARROW [] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:0048638 ! regulation of developmental growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009826 ! unidimensional cell growth +relationship: regulates GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0051511 +name: negative regulation of unidimensional cell growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] +synonym: "down regulation of unidimensional cell growth" EXACT [] +synonym: "down-regulation of unidimensional cell growth" EXACT [] +synonym: "downregulation of unidimensional cell growth" EXACT [] +synonym: "inhibition of unidimensional cell growth" NARROW [] +synonym: "negative regulation of cell elongation" NARROW [] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0051510 ! regulation of unidimensional cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009826 ! unidimensional cell growth +relationship: negatively_regulates GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0051512 +name: positive regulation of unidimensional cell growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] +synonym: "activation of unidimensional cell growth" NARROW [] +synonym: "positive regulation of cell elongation" NARROW [] +synonym: "stimulation of unidimensional cell growth" NARROW [] +synonym: "up regulation of unidimensional cell growth" EXACT [] +synonym: "up-regulation of unidimensional cell growth" EXACT [] +synonym: "upregulation of unidimensional cell growth" EXACT [] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0051510 ! regulation of unidimensional cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009826 ! unidimensional cell growth +relationship: positively_regulates GO:0009826 ! unidimensional cell growth + +[Term] +id: GO:0051513 +name: regulation of monopolar cell growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] +is_a: GO:0051510 ! regulation of unidimensional cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042814 ! monopolar cell growth +relationship: regulates GO:0042814 ! monopolar cell growth + +[Term] +id: GO:0051514 +name: negative regulation of monopolar cell growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] +synonym: "down regulation of monopolar cell growth" EXACT [] +synonym: "down-regulation of monopolar cell growth" EXACT [] +synonym: "downregulation of monopolar cell growth" EXACT [] +synonym: "inhibition of monopolar cell growth" NARROW [] +is_a: GO:0051511 ! negative regulation of unidimensional cell growth +is_a: GO:0051513 ! regulation of monopolar cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042814 ! monopolar cell growth +relationship: negatively_regulates GO:0042814 ! monopolar cell growth + +[Term] +id: GO:0051515 +name: positive regulation of monopolar cell growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] +synonym: "stimulation of monopolar cell growth" NARROW [] +synonym: "up regulation of monopolar cell growth" EXACT [] +synonym: "up-regulation of monopolar cell growth" EXACT [] +synonym: "upregulation of monopolar cell growth" EXACT [] +is_a: GO:0051512 ! positive regulation of unidimensional cell growth +is_a: GO:0051513 ! regulation of monopolar cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042814 ! monopolar cell growth +relationship: positively_regulates GO:0042814 ! monopolar cell growth + +[Term] +id: GO:0051516 +name: regulation of bipolar cell growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] +is_a: GO:0051510 ! regulation of unidimensional cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042815 ! bipolar cell growth +relationship: regulates GO:0042815 ! bipolar cell growth + +[Term] +id: GO:0051517 +name: negative regulation of bipolar cell growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] +synonym: "down regulation of bipolar cell growth" EXACT [] +synonym: "down-regulation of bipolar cell growth" EXACT [] +synonym: "downregulation of bipolar cell growth" EXACT [] +synonym: "inhibition of bipolar cell growth" NARROW [] +is_a: GO:0051511 ! negative regulation of unidimensional cell growth +is_a: GO:0051516 ! regulation of bipolar cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042815 ! bipolar cell growth +relationship: negatively_regulates GO:0042815 ! bipolar cell growth + +[Term] +id: GO:0051518 +name: positive regulation of bipolar cell growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] +synonym: "stimulation of bipolar cell growth" NARROW [] +synonym: "up regulation of bipolar cell growth" EXACT [] +synonym: "up-regulation of bipolar cell growth" EXACT [] +synonym: "upregulation of bipolar cell growth" EXACT [] +is_a: GO:0051512 ! positive regulation of unidimensional cell growth +is_a: GO:0051516 ! regulation of bipolar cell growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042815 ! bipolar cell growth +relationship: positively_regulates GO:0042815 ! bipolar cell growth + +[Term] +id: GO:0051519 +name: activation of bipolar cell growth +namespace: biological_process +def: "Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] +is_a: GO:0051518 ! positive regulation of bipolar cell growth + +[Term] +id: GO:0051520 +name: termination of bipolar cell growth +namespace: biological_process +def: "Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] +is_a: GO:0051517 ! negative regulation of bipolar cell growth + +[Term] +id: GO:0051521 +name: termination of monopolar cell growth +namespace: biological_process +def: "Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell." [GOC:ai] +is_a: GO:0051514 ! negative regulation of monopolar cell growth + +[Term] +id: GO:0051522 +name: activation of monopolar cell growth +namespace: biological_process +def: "Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] +is_a: GO:0051515 ! positive regulation of monopolar cell growth + +[Term] +id: GO:0051523 +name: cell growth mode switching, monopolar to bipolar +namespace: biological_process +def: "The process in which a cell switches from monopolar cell growth to bipolar cell growth." [GOC:ai] +synonym: "NETO" NARROW [GOC:vw] +synonym: "new end take off" NARROW [GOC:vw] +is_a: GO:0061171 ! establishment of bipolar cell polarity +is_a: GO:0061389 ! regulation of direction of cell growth + +[Term] +id: GO:0051524 +name: cell growth mode switching, bipolar to monopolar +namespace: biological_process +def: "The process in which a cell switches from bipolar cell growth to monopolar cell growth." [GOC:ai] +is_a: GO:0061162 ! establishment of monopolar cell polarity +is_a: GO:0061389 ! regulation of direction of cell growth + +[Term] +id: GO:0051525 +name: NFAT protein binding +namespace: molecular_function +alt_id: GO:0051526 +alt_id: GO:0051527 +alt_id: GO:0051528 +alt_id: GO:0051529 +alt_id: GO:0051530 +def: "Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system." [PMID:15928679] +synonym: "NFAT binding" EXACT [] +synonym: "NFAT1 protein binding" NARROW [] +synonym: "NFAT2 protein binding" NARROW [] +synonym: "NFAT3 protein binding" NARROW [] +synonym: "NFAT4 protein binding" NARROW [] +synonym: "NFAT5 protein binding" NARROW [] +synonym: "NFATc binding" NARROW [] +synonym: "NFATc1 binding" NARROW [] +synonym: "NFATc2 binding" NARROW [] +synonym: "NFATc3 binding" NARROW [] +synonym: "NFATc4 binding" NARROW [] +synonym: "NFATp binding" NARROW [] +synonym: "NFATx binding" NARROW [] +synonym: "non-calcium-regulated NFAT protein binding" NARROW [] +synonym: "nuclear factor of activated T cell protein binding" EXACT [] +is_a: GO:0061629 ! RNA polymerase II-specific DNA-binding transcription factor binding + +[Term] +id: GO:0051536 +name: iron-sulfur cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms." [GOC:ai] +subset: goslim_metagenomics +synonym: "Fe/S binding" EXACT [] +synonym: "iron sulfur cluster binding" EXACT [] +synonym: "iron sulphur cluster binding" EXACT [] +synonym: "iron-sulphur cluster binding" EXACT [] +is_a: GO:0048037 ! cofactor binding +is_a: GO:0051540 ! metal cluster binding + +[Term] +id: GO:0051537 +name: 2 iron, 2 sulfur cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands." [GOC:ai, PMID:15952888, Wikipedia:Iron-sulfur_cluster] +synonym: "2 Fe 2 S cluster binding" EXACT [] +synonym: "2 iron, 2 sulphur cluster binding" EXACT [] +synonym: "2Fe-2S cluster binding" EXACT [] +synonym: "diiron disulfide cluster binding" EXACT [] +synonym: "diiron disulphide cluster binding" EXACT [] +synonym: "iron-sulfur cluster 2Fe-2S binding" EXACT [] +synonym: "iron-sulphur cluster 2Fe-2S binding" EXACT [] +is_a: GO:0051536 ! iron-sulfur cluster binding + +[Term] +id: GO:0051538 +name: 3 iron, 4 sulfur cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing." [GOC:ai, PMID:15952888, Wikipedia:Iron-sulfur_cluster] +synonym: "3 Fe 4 S cluster binding" EXACT [] +synonym: "3 iron, 4 sulphur cluster binding" EXACT [] +synonym: "3Fe-4S cluster binding" EXACT [] +synonym: "iron-sulfur cluster 3Fe-4S binding" EXACT [] +synonym: "iron-sulphur cluster 3Fe-4S binding" EXACT [] +synonym: "triiron tetrasulfide cluster binding" EXACT [] +synonym: "triiron tetrasulphide cluster binding" EXACT [] +is_a: GO:0051536 ! iron-sulfur cluster binding + +[Term] +id: GO:0051539 +name: 4 iron, 4 sulfur cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands." [GOC:ai, PMID:15952888, Wikipedia:Iron-sulfur_cluster] +synonym: "4 Fe 4 S cluster binding" EXACT [] +synonym: "4 iron, 4 sulphur cluster binding" EXACT [] +synonym: "4Fe-4S cluster binding" EXACT [] +synonym: "iron-sulfur cluster 4Fe-4S binding" EXACT [] +synonym: "iron-sulphur cluster 4Fe-4S binding" EXACT [] +synonym: "tetrairon tetrasulfide cluster binding" EXACT [] +synonym: "tetrairon tetrasulphide cluster binding" EXACT [] +is_a: GO:0051536 ! iron-sulfur cluster binding + +[Term] +id: GO:0051540 +name: metal cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters." [GOC:jsg] +subset: goslim_pir +is_a: GO:0005488 ! binding + +[Term] +id: GO:0051541 +name: elastin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue." [GOC:curators] +synonym: "elastin metabolism" EXACT [] +is_a: GO:0009100 ! glycoprotein metabolic process + +[Term] +id: GO:0051542 +name: elastin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries." [GOC:ai] +is_a: GO:0009101 ! glycoprotein biosynthetic process +is_a: GO:0051541 ! elastin metabolic process + +[Term] +id: GO:0051543 +name: regulation of elastin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051542 ! elastin biosynthetic process +relationship: regulates GO:0051542 ! elastin biosynthetic process + +[Term] +id: GO:0051544 +name: positive regulation of elastin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] +synonym: "activation of elastin biosynthetic process" NARROW [] +synonym: "stimulation of elastin biosynthetic process" NARROW [] +synonym: "up regulation of elastin biosynthetic process" EXACT [] +synonym: "up-regulation of elastin biosynthetic process" EXACT [] +synonym: "upregulation of elastin biosynthetic process" EXACT [] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0051543 ! regulation of elastin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051542 ! elastin biosynthetic process +relationship: positively_regulates GO:0051542 ! elastin biosynthetic process + +[Term] +id: GO:0051545 +name: negative regulation of elastin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] +synonym: "down regulation of elastin biosynthetic process" EXACT [] +synonym: "down-regulation of elastin biosynthetic process" EXACT [] +synonym: "downregulation of elastin biosynthetic process" EXACT [] +synonym: "inhibition of elastin biosynthetic process" NARROW [] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0051543 ! regulation of elastin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051542 ! elastin biosynthetic process +relationship: negatively_regulates GO:0051542 ! elastin biosynthetic process + +[Term] +id: GO:0051546 +name: keratinocyte migration +namespace: biological_process +def: "The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another." [ISBN:0721662544] +is_a: GO:0010631 ! epithelial cell migration + +[Term] +id: GO:0051547 +name: regulation of keratinocyte migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of keratinocyte migration." [GOC:ai] +is_a: GO:0010632 ! regulation of epithelial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051546 ! keratinocyte migration +relationship: regulates GO:0051546 ! keratinocyte migration + +[Term] +id: GO:0051548 +name: negative regulation of keratinocyte migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration." [GOC:ai] +synonym: "down regulation of keratinocyte migration" EXACT [] +synonym: "down-regulation of keratinocyte migration" EXACT [] +synonym: "downregulation of keratinocyte migration" EXACT [] +synonym: "inhibition of keratinocyte migration" NARROW [] +is_a: GO:0010633 ! negative regulation of epithelial cell migration +is_a: GO:0051547 ! regulation of keratinocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051546 ! keratinocyte migration +relationship: negatively_regulates GO:0051546 ! keratinocyte migration + +[Term] +id: GO:0051549 +name: positive regulation of keratinocyte migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of keratinocyte migration." [GOC:ai] +synonym: "activation of keratinocyte migration" NARROW [] +synonym: "stimulation of keratinocyte migration" NARROW [] +synonym: "up regulation of keratinocyte migration" EXACT [] +synonym: "up-regulation of keratinocyte migration" EXACT [] +synonym: "upregulation of keratinocyte migration" EXACT [] +is_a: GO:0010634 ! positive regulation of epithelial cell migration +is_a: GO:0051547 ! regulation of keratinocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051546 ! keratinocyte migration +relationship: positively_regulates GO:0051546 ! keratinocyte migration + +[Term] +id: GO:0051550 +name: aurone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides." [PMID:20035037] +synonym: "aurone metabolism" EXACT [] +synonym: "benzalcoumaran-3-one metabolic process" EXACT [] +synonym: "benzalcoumaran-3-one metabolism" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042440 ! pigment metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process + +[Term] +id: GO:0051551 +name: aurone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments." [GOC:ai, PMID:20035037] +synonym: "benzalcoumaran-3-one biosynthesis" EXACT [] +synonym: "benzalcoumaran-3-one biosynthetic process" EXACT [] +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0051550 ! aurone metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process + +[Term] +id: GO:0051552 +name: flavone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)." [PMID:18567791] +synonym: "2-phenyl-4H-1-benzopyran-4-one metabolic process" NARROW [] +synonym: "2-phenyl-4H-1-benzopyran-4-one metabolism" NARROW [] +synonym: "2-phenylchromone metabolic process" NARROW [] +synonym: "2-phenylchromone metabolism" NARROW [] +synonym: "flavone metabolism" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0051553 +name: flavone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)." [GOC:ai, PMID:18567791] +synonym: "2-phenyl-4H-1-benzopyran-4-one biosynthesis" NARROW [] +synonym: "2-phenyl-4H-1-benzopyran-4-one biosynthetic process" NARROW [] +synonym: "2-phenylchromone biosynthesis" NARROW [] +synonym: "2-phenylchromone biosynthetic process" NARROW [] +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0051552 ! flavone metabolic process + +[Term] +id: GO:0051554 +name: flavonol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities." [PMID:11402179] +synonym: "flavonol metabolism" EXACT [] +is_a: GO:0051552 ! flavone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0051555 +name: flavonol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities." [GOC:ai] +xref: MetaCyc:PWY-3101 +is_a: GO:0051553 ! flavone biosynthetic process +is_a: GO:0051554 ! flavonol metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0051556 +name: leucoanthocyanidin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids." [GOC:ai] +synonym: "leucoanthocyanidin metabolism" EXACT [] +xref: MetaCyc:PWY1F-823 +is_a: GO:0009698 ! phenylpropanoid metabolic process +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process + +[Term] +id: GO:0051557 +name: leucoanthocyanidin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids." [GOC:ai] +is_a: GO:0009699 ! phenylpropanoid biosynthetic process +is_a: GO:0009813 ! flavonoid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0051556 ! leucoanthocyanidin metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process + +[Term] +id: GO:0051558 +name: phlobaphene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols." [PMID:11402179] +synonym: "phlobaphene metabolism" EXACT [] +is_a: GO:0042440 ! pigment metabolic process + +[Term] +id: GO:0051559 +name: phlobaphene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols." [PMID:11402179] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0046148 ! pigment biosynthetic process +is_a: GO:0051558 ! phlobaphene metabolic process + +[Term] +id: GO:0051560 +name: mitochondrial calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings." [GOC:ai, GOC:mah] +synonym: "calcium ion homeostasis in mitochondria" EXACT [] +synonym: "calcium ion homeostasis in mitochondrion" EXACT [] +synonym: "mitochondrial calcium ion concentration regulation" EXACT [] +synonym: "regulation of calcium ion concentration in mitochondria" EXACT [] +synonym: "regulation of calcium ion concentration in mitochondrion" EXACT [] +synonym: "regulation of mitochondrial calcium ion concentration" EXACT [] +is_a: GO:0006874 ! cellular calcium ion homeostasis +intersection_of: GO:0055074 ! calcium ion homeostasis +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0051561 +name: positive regulation of mitochondrial calcium ion concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in mitochondria." [GOC:ai] +synonym: "elevation of calcium ion concentration in mitochondria" EXACT [] +synonym: "elevation of calcium ion concentration in mitochondrion" EXACT [] +synonym: "elevation of mitochondrial calcium ion concentration" EXACT [] +synonym: "mitochondrial calcium ion concentration elevation" EXACT [] +is_a: GO:0051560 ! mitochondrial calcium ion homeostasis + +[Term] +id: GO:0051562 +name: negative regulation of mitochondrial calcium ion concentration +namespace: biological_process +def: "Any process that decreases the concentration of calcium ions in mitochondria." [GOC:ai] +synonym: "mitochondrial calcium ion concentration reduction" EXACT [] +synonym: "reduction of calcium ion concentration in mitochondria" EXACT [] +synonym: "reduction of calcium ion concentration in mitochondrion" EXACT [] +synonym: "reduction of mitochondrial calcium ion concentration" EXACT [] +is_a: GO:0051560 ! mitochondrial calcium ion homeostasis + +[Term] +id: GO:0051563 +name: smooth endoplasmic reticulum calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings." [GOC:ai, GOC:mah] +synonym: "calcium ion homeostasis in smooth endoplasmic reticulum" EXACT [] +synonym: "calcium ion homeostasis in smooth ER" EXACT [] +synonym: "regulation of calcium ion concentration in smooth endoplasmic reticulum" EXACT [] +synonym: "regulation of calcium ion concentration in smooth ER" EXACT [] +synonym: "regulation of smooth endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "regulation of smooth ER calcium ion concentration" EXACT [] +synonym: "smooth endoplasmic reticulum calcium ion concentration regulation" EXACT [] +synonym: "smooth ER calcium ion concentration regulation" EXACT [] +synonym: "smooth ER calcium ion homeostasis" EXACT [] +is_a: GO:0032469 ! endoplasmic reticulum calcium ion homeostasis +intersection_of: GO:0055074 ! calcium ion homeostasis +intersection_of: occurs_in GO:0005790 ! smooth endoplasmic reticulum +relationship: occurs_in GO:0005790 ! smooth endoplasmic reticulum + +[Term] +id: GO:0051564 +name: positive regulation of smooth endoplasmic reticulum calcium ion concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum." [GOC:ai] +synonym: "elevation of calcium ion concentration in smooth endoplasmic reticulum" EXACT [] +synonym: "elevation of smooth endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "elevation of smooth ER calcium ion concentration" EXACT [] +synonym: "smooth endoplasmic reticulum calcium ion concentration elevation" EXACT [] +is_a: GO:0032470 ! positive regulation of endoplasmic reticulum calcium ion concentration +is_a: GO:0051563 ! smooth endoplasmic reticulum calcium ion homeostasis + +[Term] +id: GO:0051565 +name: negative regulation of smooth endoplasmic reticulum calcium ion concentration +namespace: biological_process +def: "Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum." [GOC:ai] +synonym: "reduction of calcium ion concentration in smooth endoplasmic reticulum" EXACT [] +synonym: "reduction of calcium ion concentration in smooth ER" EXACT [] +synonym: "reduction of smooth endoplasmic reticulum calcium ion concentration" EXACT [] +synonym: "reduction of smooth ER calcium ion concentration" EXACT [] +synonym: "smooth endoplasmic reticulum calcium ion concentration reduction" EXACT [] +synonym: "smooth ER calcium ion concentration reduction" EXACT [] +is_a: GO:0032471 ! negative regulation of endoplasmic reticulum calcium ion concentration +is_a: GO:0051563 ! smooth endoplasmic reticulum calcium ion homeostasis + +[Term] +id: GO:0051566 +name: anthocyanidin-3-glucoside rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP." [PMID:8130800] +synonym: "3RT activity" BROAD [] +synonym: "anthocyanidin 3-glucoside-rhamnosyltransferase activity" EXACT [] +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0051567 +name: histone H3-K9 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone." [GOC:ai, GOC:pr] +synonym: "histone H3 K9 methylation" EXACT [] +synonym: "histone H3K9me" EXACT [] +synonym: "histone lysine H3 K9 methylation" EXACT [] +is_a: GO:0034968 ! histone lysine methylation +is_a: GO:0061647 ! histone H3-K9 modification + +[Term] +id: GO:0051568 +name: histone H3-K4 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone." [GOC:ai, GOC:pr] +synonym: "histone H3 K4 methylation" EXACT [] +synonym: "histone H3K4me" EXACT [] +synonym: "histone lysine H3 K4 methylation" EXACT [] +is_a: GO:0034968 ! histone lysine methylation + +[Term] +id: GO:0051569 +name: regulation of histone H3-K4 methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:ai] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051568 ! histone H3-K4 methylation +relationship: regulates GO:0051568 ! histone H3-K4 methylation + +[Term] +id: GO:0051570 +name: regulation of histone H3-K9 methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051567 ! histone H3-K9 methylation +relationship: regulates GO:0051567 ! histone H3-K9 methylation + +[Term] +id: GO:0051571 +name: positive regulation of histone H3-K4 methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:mah] +synonym: "activation of histone H3-K4 methylation" NARROW [] +synonym: "stimulation of histone H3-K4 methylation" NARROW [] +synonym: "up regulation of histone H3-K4 methylation" EXACT [] +synonym: "up-regulation of histone H3-K4 methylation" EXACT [] +synonym: "upregulation of histone H3-K4 methylation" EXACT [] +is_a: GO:0031062 ! positive regulation of histone methylation +is_a: GO:0051569 ! regulation of histone H3-K4 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051568 ! histone H3-K4 methylation +relationship: positively_regulates GO:0051568 ! histone H3-K4 methylation + +[Term] +id: GO:0051572 +name: negative regulation of histone H3-K4 methylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:mah] +synonym: "down regulation of histone H3-K4 methylation" EXACT [] +synonym: "down-regulation of histone H3-K4 methylation" EXACT [] +synonym: "downregulation of histone H3-K4 methylation" EXACT [] +synonym: "inhibition of histone H3-K4 methylation" NARROW [] +is_a: GO:0031061 ! negative regulation of histone methylation +is_a: GO:0051569 ! regulation of histone H3-K4 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051568 ! histone H3-K4 methylation +relationship: negatively_regulates GO:0051568 ! histone H3-K4 methylation + +[Term] +id: GO:0051573 +name: negative regulation of histone H3-K9 methylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] +synonym: "down regulation of histone H3-K9 methylation" EXACT [] +synonym: "down-regulation of histone H3-K9 methylation" EXACT [] +synonym: "downregulation of histone H3-K9 methylation" EXACT [] +synonym: "inhibition of histone H3-K9 methylation" NARROW [] +is_a: GO:0031061 ! negative regulation of histone methylation +is_a: GO:0051570 ! regulation of histone H3-K9 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051567 ! histone H3-K9 methylation +relationship: negatively_regulates GO:0051567 ! histone H3-K9 methylation + +[Term] +id: GO:0051574 +name: positive regulation of histone H3-K9 methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] +synonym: "activation of histone H3-K9 methylation" NARROW [] +synonym: "stimulation of histone H3-K9 methylation" NARROW [] +synonym: "up regulation of histone H3-K9 methylation" EXACT [] +synonym: "up-regulation of histone H3-K9 methylation" EXACT [] +synonym: "upregulation of histone H3-K9 methylation" EXACT [] +is_a: GO:0031062 ! positive regulation of histone methylation +is_a: GO:0051570 ! regulation of histone H3-K9 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051567 ! histone H3-K9 methylation +relationship: positively_regulates GO:0051567 ! histone H3-K9 methylation + +[Term] +id: GO:0051575 +name: 5'-deoxyribose-5-phosphate lyase activity +namespace: molecular_function +def: "Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site." [PMID:11251121, PMID:16120966] +synonym: "5'-deoxyribose phosphate activity" EXACT [] +synonym: "dRP lyase activity" BROAD [] +synonym: "dRPase activity" BROAD [] +is_a: GO:0016835 ! carbon-oxygen lyase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0051580 +name: regulation of neurotransmitter uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell." [GOC:ai] +subset: goslim_synapse +synonym: "regulation of neurotransmitter import" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of neurotransmitter reuptake" EXACT [] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0051588 ! regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001504 ! neurotransmitter uptake +relationship: regulates GO:0001504 ! neurotransmitter uptake + +[Term] +id: GO:0051581 +name: negative regulation of neurotransmitter uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell." [GOC:ai] +synonym: "down regulation of neurotransmitter uptake" EXACT [] +synonym: "down-regulation of neurotransmitter uptake" EXACT [] +synonym: "downregulation of neurotransmitter uptake" EXACT [] +synonym: "negative regulation of neurotransmitter import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001504 ! neurotransmitter uptake +relationship: negatively_regulates GO:0001504 ! neurotransmitter uptake + +[Term] +id: GO:0051582 +name: positive regulation of neurotransmitter uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell." [GOC:ai] +synonym: "activation of neurotransmitter uptake" NARROW [] +synonym: "positive regulation of neurotransmitter import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of neurotransmitter uptake" NARROW [] +synonym: "up regulation of neurotransmitter uptake" EXACT [] +synonym: "up-regulation of neurotransmitter uptake" EXACT [] +synonym: "upregulation of neurotransmitter uptake" EXACT [] +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001504 ! neurotransmitter uptake +relationship: positively_regulates GO:0001504 ! neurotransmitter uptake + +[Term] +id: GO:0051583 +name: dopamine uptake involved in synaptic transmission +namespace: biological_process +def: "The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:ai] +synonym: "dopamine import involved in synaptic transmission" EXACT [GOC:dph, GOC:tb] +synonym: "dopamine reuptake involved in synaptic transmission" EXACT [] +is_a: GO:0051934 ! catecholamine uptake involved in synaptic transmission +is_a: GO:0090494 ! dopamine uptake +relationship: part_of GO:0001963 ! synaptic transmission, dopaminergic + +[Term] +id: GO:0051584 +name: regulation of dopamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell." [GOC:ai] +synonym: "regulation of dopamine import involved in synaptic transmission" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032225 ! regulation of synaptic transmission, dopaminergic +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051940 ! regulation of catecholamine uptake involved in synaptic transmission +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051583 ! dopamine uptake involved in synaptic transmission +relationship: regulates GO:0051583 ! dopamine uptake involved in synaptic transmission + +[Term] +id: GO:0051585 +name: negative regulation of dopamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell." [GOC:ai] +synonym: "down regulation of dopamine uptake involved in synaptic transmission" EXACT [] +synonym: "down-regulation of dopamine uptake involved in synaptic transmission" EXACT [] +synonym: "downregulation of dopamine uptake involved in synaptic transmission" EXACT [] +synonym: "negative regulation of dopamine import involved in synaptic transmission" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032227 ! negative regulation of synaptic transmission, dopaminergic +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0051584 ! regulation of dopamine uptake involved in synaptic transmission +is_a: GO:0051945 ! negative regulation of catecholamine uptake involved in synaptic transmission +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051583 ! dopamine uptake involved in synaptic transmission +relationship: negatively_regulates GO:0051583 ! dopamine uptake involved in synaptic transmission + +[Term] +id: GO:0051586 +name: positive regulation of dopamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell." [GOC:ai] +synonym: "activation of dopamine uptake involved in synaptic transmission" NARROW [] +synonym: "positive regulation of dopamine import involved in synaptic transmission" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of dopamine uptake involved in synaptic transmission" NARROW [] +synonym: "up regulation of dopamine uptake involved in synaptic transmission" EXACT [] +synonym: "up-regulation of dopamine uptake involved in synaptic transmission" EXACT [] +synonym: "upregulation of dopamine uptake involved in synaptic transmission" EXACT [] +is_a: GO:0032226 ! positive regulation of synaptic transmission, dopaminergic +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051584 ! regulation of dopamine uptake involved in synaptic transmission +is_a: GO:0051944 ! positive regulation of catecholamine uptake involved in synaptic transmission +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051583 ! dopamine uptake involved in synaptic transmission +relationship: positively_regulates GO:0051583 ! dopamine uptake involved in synaptic transmission + +[Term] +id: GO:0051587 +name: inhibition of dopamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of dopamine into a cell." [GOC:ai] +synonym: "inhibition of dopamine import involved in synaptic transmission" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051585 ! negative regulation of dopamine uptake involved in synaptic transmission +is_a: GO:0051609 ! inhibition of neurotransmitter uptake + +[Term] +id: GO:0051588 +name: regulation of neurotransmitter transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006836 ! neurotransmitter transport +relationship: regulates GO:0006836 ! neurotransmitter transport + +[Term] +id: GO:0051589 +name: negative regulation of neurotransmitter transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of neurotransmitter transport" EXACT [] +synonym: "down-regulation of neurotransmitter transport" EXACT [] +synonym: "downregulation of neurotransmitter transport" EXACT [] +synonym: "inhibition of neurotransmitter transport" NARROW [] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051588 ! regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006836 ! neurotransmitter transport +relationship: negatively_regulates GO:0006836 ! neurotransmitter transport + +[Term] +id: GO:0051590 +name: positive regulation of neurotransmitter transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of neurotransmitter transport" NARROW [] +synonym: "stimulation of neurotransmitter transport" NARROW [] +synonym: "up regulation of neurotransmitter transport" EXACT [] +synonym: "up-regulation of neurotransmitter transport" EXACT [] +synonym: "upregulation of neurotransmitter transport" EXACT [] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051588 ! regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006836 ! neurotransmitter transport +relationship: positively_regulates GO:0006836 ! neurotransmitter transport + +[Term] +id: GO:0051591 +name: response to cAMP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus." [GOC:ai] +synonym: "response to 3',5' cAMP" EXACT [] +synonym: "response to 3',5'-cAMP" EXACT [] +synonym: "response to adenosine 3',5'-cyclophosphate" EXACT [] +synonym: "response to cyclic AMP" EXACT [] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0051592 +name: response to calcium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." [GOC:ai] +synonym: "response to Ca2+ ion" EXACT [] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0051593 +name: response to folic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus." [GOC:ai] +synonym: "cellular response to folate" EXACT [GOC:mah] +synonym: "cellular response to vitamin B9" EXACT [GOC:mah] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0051594 +name: detection of glucose +namespace: biological_process +def: "The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal." [GOC:ai] +synonym: "glucose detection" EXACT [] +synonym: "glucose perception" RELATED [] +synonym: "glucose sensing" RELATED [] +is_a: GO:0009732 ! detection of hexose stimulus +is_a: GO:0009749 ! response to glucose + +[Term] +id: GO:0051595 +name: response to methylglyoxal +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal." [GOC:ai] +synonym: "response to pyruvaldehyde" EXACT [] +is_a: GO:1901654 ! response to ketone + +[Term] +id: GO:0051596 +name: methylglyoxal catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid." [GOC:ai] +synonym: "methylglyoxal breakdown" EXACT [] +synonym: "methylglyoxal catabolism" EXACT [] +synonym: "methylglyoxal degradation" EXACT [] +xref: MetaCyc:METHGLYUT-PWY +xref: MetaCyc:Methylglyoxal-Detoxification +is_a: GO:0009438 ! methylglyoxal metabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046185 ! aldehyde catabolic process + +[Term] +id: GO:0051597 +name: response to methylmercury +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus." [GOC:ai] +synonym: "response to CH3-Hg+" EXACT [] +synonym: "response to MeHg+" EXACT [] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:0051598 +name: meiotic recombination checkpoint +namespace: biological_process +def: "A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes." [PMID:14718568] +synonym: "pachytene checkpoint" EXACT [] +is_a: GO:0033313 ! meiotic cell cycle checkpoint +is_a: GO:0045835 ! negative regulation of meiotic nuclear division + +[Term] +id: GO:0051599 +name: response to hydrostatic pressure +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it." [Wikipedia:Hydrostatic_pressure] +synonym: "response to biomechanical stress" BROAD [] +synonym: "response to static fluid pressure" EXACT [] +is_a: GO:0006950 ! response to stress +is_a: GO:0009415 ! response to water + +[Term] +id: GO:0051600 +name: regulation of endocytosis by exocyst localization +namespace: biological_process +def: "Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse." [GOC:ai, GOC:dph, GOC:tb] +synonym: "regulation of endocytosis by exocyst localisation" EXACT [GOC:mah] +synonym: "regulation of site selection of endocytosis" RELATED [] +synonym: "relocation of endocytosis" RELATED [] +synonym: "spatial regulation of endocytosis" RELATED [] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:0051601 ! exocyst localization +intersection_of: GO:0051601 ! exocyst localization +intersection_of: regulates GO:0006897 ! endocytosis + +[Term] +id: GO:0051601 +name: exocyst localization +namespace: biological_process +def: "Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse." [GOC:ai] +synonym: "establishment and maintenance of exocyst localization" EXACT [] +synonym: "exocyst localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization + +[Term] +id: GO:0051602 +name: response to electrical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai] +synonym: "response to electricity" RELATED [] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0051603 +name: proteolysis involved in cellular protein catabolic process +namespace: biological_process +def: "The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_yeast +synonym: "peptidolysis during cellular protein catabolic process" RELATED [] +synonym: "peptidolysis during cellular protein catabolism" RELATED [] +synonym: "peptidolysis involved in cellular protein catabolic process" EXACT [] +synonym: "peptidolysis involved in cellular protein catabolism" EXACT [] +synonym: "proteolysis during cellular protein catabolic process" RELATED [] +synonym: "proteolysis during cellular protein catabolism" RELATED [] +is_a: GO:0006508 ! proteolysis +intersection_of: GO:0006508 ! proteolysis +intersection_of: part_of GO:0044257 ! cellular protein catabolic process +relationship: part_of GO:0044257 ! cellular protein catabolic process + +[Term] +id: GO:0051604 +name: protein maturation +namespace: biological_process +def: "Any process leading to the attainment of the full functional capacity of a protein." [GOC:ai] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +subset: goslim_yeast +is_a: GO:0019538 ! protein metabolic process +relationship: part_of GO:0010467 ! gene expression + +[Term] +id: GO:0051606 +name: detection of stimulus +namespace: biological_process +def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah] +subset: goslim_pir +synonym: "perception of stimulus" RELATED [] +synonym: "stimulus detection" EXACT [] +synonym: "stimulus sensing" RELATED [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0051607 +name: defense response to virus +namespace: biological_process +def: "Reactions triggered in response to the presence of a virus that act to protect the cell or organism." [GOC:ai] +synonym: "antiviral response" EXACT [] +synonym: "defence response to virus" EXACT [] +synonym: "defense response to viruses" EXACT [] +is_a: GO:0002252 ! immune effector process +is_a: GO:0009615 ! response to virus +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0051608 +name: histamine transport +namespace: biological_process +def: "The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] +is_a: GO:0006812 ! cation transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0051609 +name: inhibition of neurotransmitter uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of a neurotransmitter into a cell." [GOC:ai] +synonym: "inhibition of neurotransmitter import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake + +[Term] +id: GO:0051610 +name: serotonin uptake +namespace: biological_process +def: "The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] +synonym: "5-HT uptake" EXACT [] +synonym: "5-hydroxytryptamine uptake" EXACT [] +synonym: "5HT uptake" EXACT [] +synonym: "serotonin import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006837 ! serotonin transport +is_a: GO:0098810 ! neurotransmitter reuptake + +[Term] +id: GO:0051611 +name: regulation of serotonin uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell." [GOC:ai] +synonym: "regulation of 5-HT uptake" EXACT [] +synonym: "regulation of 5-hydroxytryptamine uptake" EXACT [] +synonym: "regulation of 5HT uptake" EXACT [] +synonym: "regulation of serotonin import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051610 ! serotonin uptake +relationship: regulates GO:0051610 ! serotonin uptake + +[Term] +id: GO:0051612 +name: negative regulation of serotonin uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell." [GOC:ai] +synonym: "down regulation of serotonin uptake" EXACT [] +synonym: "down-regulation of serotonin uptake" EXACT [] +synonym: "downregulation of serotonin uptake" EXACT [] +synonym: "negative regulation of 5-HT uptake" EXACT [] +synonym: "negative regulation of 5-hydroxytryptamine uptake" EXACT [] +synonym: "negative regulation of 5HT uptake" EXACT [] +synonym: "negative regulation of serotonin import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051611 ! regulation of serotonin uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051610 ! serotonin uptake +relationship: negatively_regulates GO:0051610 ! serotonin uptake + +[Term] +id: GO:0051613 +name: positive regulation of serotonin uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell." [GOC:ai] +synonym: "activation of serotonin uptake" NARROW [] +synonym: "positive regulation of 5-HT uptake" EXACT [] +synonym: "positive regulation of 5-hydroxytryptamine uptake" EXACT [] +synonym: "positive regulation of 5HT uptake" EXACT [] +synonym: "positive regulation of serotonin import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of serotonin uptake" NARROW [] +synonym: "up regulation of serotonin uptake" EXACT [] +synonym: "up-regulation of serotonin uptake" EXACT [] +synonym: "upregulation of serotonin uptake" EXACT [] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051611 ! regulation of serotonin uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051610 ! serotonin uptake +relationship: positively_regulates GO:0051610 ! serotonin uptake + +[Term] +id: GO:0051614 +name: inhibition of serotonin uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of serotonin into a cell." [GOC:ai] +synonym: "inhibition of 5-HT uptake" EXACT [] +synonym: "inhibition of 5-hydroxytryptamine uptake" EXACT [] +synonym: "inhibition of 5HT uptake" EXACT [] +synonym: "inhibition of serotonin import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051609 ! inhibition of neurotransmitter uptake +is_a: GO:0051612 ! negative regulation of serotonin uptake + +[Term] +id: GO:0051615 +name: histamine uptake +namespace: biological_process +def: "The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] +synonym: "histamine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001504 ! neurotransmitter uptake +is_a: GO:0051608 ! histamine transport + +[Term] +id: GO:0051616 +name: regulation of histamine uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell." [GOC:ai] +synonym: "regulation of histamine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051580 ! regulation of neurotransmitter uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051615 ! histamine uptake +relationship: regulates GO:0051615 ! histamine uptake + +[Term] +id: GO:0051617 +name: negative regulation of histamine uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell." [GOC:ai] +synonym: "down regulation of histamine uptake" EXACT [] +synonym: "down-regulation of histamine uptake" EXACT [] +synonym: "downregulation of histamine uptake" EXACT [] +synonym: "negative regulation of histamine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051616 ! regulation of histamine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051615 ! histamine uptake +relationship: negatively_regulates GO:0051615 ! histamine uptake + +[Term] +id: GO:0051618 +name: positive regulation of histamine uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell." [GOC:ai] +synonym: "activation of histamine uptake" NARROW [] +synonym: "positive regulation of histamine import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of histamine uptake" NARROW [] +synonym: "up regulation of histamine uptake" EXACT [] +synonym: "up-regulation of histamine uptake" EXACT [] +synonym: "upregulation of histamine uptake" EXACT [] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051616 ! regulation of histamine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051615 ! histamine uptake +relationship: positively_regulates GO:0051615 ! histamine uptake + +[Term] +id: GO:0051619 +name: inhibition of histamine uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of histamine into a cell." [GOC:ai] +synonym: "inhibition of histamine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051609 ! inhibition of neurotransmitter uptake +is_a: GO:0051617 ! negative regulation of histamine uptake + +[Term] +id: GO:0051620 +name: norepinephrine uptake +namespace: biological_process +def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] +synonym: "levarterenol reuptake" EXACT [] +synonym: "levarterenol uptake" EXACT [] +synonym: "noradrenaline reuptake" EXACT [] +synonym: "noradrenaline uptake" EXACT [] +synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb] +synonym: "norepinephrine reuptake" EXACT [] +is_a: GO:0015874 ! norepinephrine transport +is_a: GO:0090493 ! catecholamine uptake + +[Term] +id: GO:0051621 +name: regulation of norepinephrine uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai] +synonym: "regulation of levarterenol uptake" EXACT [] +synonym: "regulation of noradrenaline uptake" EXACT [] +synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051620 ! norepinephrine uptake +relationship: regulates GO:0051620 ! norepinephrine uptake + +[Term] +id: GO:0051622 +name: negative regulation of norepinephrine uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] +synonym: "down regulation of norepinephrine uptake" EXACT [] +synonym: "down-regulation of norepinephrine uptake" EXACT [] +synonym: "downregulation of norepinephrine uptake" EXACT [] +synonym: "negative regulation of levarterenol uptake" EXACT [] +synonym: "negative regulation of noradrenaline uptake" EXACT [] +synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051621 ! regulation of norepinephrine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051620 ! norepinephrine uptake +relationship: negatively_regulates GO:0051620 ! norepinephrine uptake + +[Term] +id: GO:0051623 +name: positive regulation of norepinephrine uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] +synonym: "activation of norepinephrine uptake" NARROW [] +synonym: "positive regulation of levarterenol uptake" EXACT [] +synonym: "positive regulation of noradrenaline uptake" EXACT [] +synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of norepinephrine uptake" NARROW [] +synonym: "up regulation of norepinephrine uptake" EXACT [] +synonym: "up-regulation of norepinephrine uptake" EXACT [] +synonym: "upregulation of norepinephrine uptake" EXACT [] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051621 ! regulation of norepinephrine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051620 ! norepinephrine uptake +relationship: positively_regulates GO:0051620 ! norepinephrine uptake + +[Term] +id: GO:0051624 +name: inhibition of norepinephrine uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of norepinephrine into a cell." [GOC:ai] +synonym: "inhibition of levarterenol uptake" EXACT [] +synonym: "inhibition of noradrenaline uptake" EXACT [] +synonym: "inhibition of norepinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051609 ! inhibition of neurotransmitter uptake +is_a: GO:0051622 ! negative regulation of norepinephrine uptake + +[Term] +id: GO:0051625 +name: epinephrine uptake +namespace: biological_process +def: "The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:ai] +synonym: "adrenaline reuptake" EXACT [] +synonym: "adrenaline uptake" EXACT [] +synonym: "epinephrine import" EXACT [GOC:dph, GOC:tb] +synonym: "epinephrine reuptake" EXACT [] +is_a: GO:0048241 ! epinephrine transport +is_a: GO:0090493 ! catecholamine uptake + +[Term] +id: GO:0051626 +name: regulation of epinephrine uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell." [GOC:ai] +synonym: "regulation of adrenaline uptake" EXACT [] +synonym: "regulation of epinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051625 ! epinephrine uptake +relationship: regulates GO:0051625 ! epinephrine uptake + +[Term] +id: GO:0051627 +name: negative regulation of epinephrine uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell." [GOC:ai] +synonym: "down regulation of epinephrine uptake" EXACT [] +synonym: "down-regulation of epinephrine uptake" EXACT [] +synonym: "downregulation of epinephrine uptake" EXACT [] +synonym: "negative regulation of adrenaline uptake" EXACT [] +synonym: "negative regulation of epinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051626 ! regulation of epinephrine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051625 ! epinephrine uptake +relationship: negatively_regulates GO:0051625 ! epinephrine uptake + +[Term] +id: GO:0051628 +name: positive regulation of epinephrine uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell." [GOC:ai] +synonym: "activation of epinephrine uptake" NARROW [] +synonym: "positive regulation of adrenaline uptake" EXACT [] +synonym: "positive regulation of epinephrine import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of epinephrine uptake" NARROW [] +synonym: "up regulation of epinephrine uptake" EXACT [] +synonym: "up-regulation of epinephrine uptake" EXACT [] +synonym: "upregulation of epinephrine uptake" EXACT [] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051626 ! regulation of epinephrine uptake +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051625 ! epinephrine uptake +relationship: positively_regulates GO:0051625 ! epinephrine uptake + +[Term] +id: GO:0051629 +name: inhibition of epinephrine uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of epinephrine into a cell." [GOC:ai] +synonym: "inhibition of adrenaline uptake" EXACT [] +synonym: "inhibition of epinephrine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051609 ! inhibition of neurotransmitter uptake +is_a: GO:0051627 ! negative regulation of epinephrine uptake + +[Term] +id: GO:0051630 +name: acetylcholine uptake +namespace: biological_process +def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] +synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015870 ! acetylcholine transport +is_a: GO:0098657 ! import into cell + +[Term] +id: GO:0051631 +name: regulation of acetylcholine uptake +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai] +synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:0051952 ! regulation of amine transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051630 ! acetylcholine uptake +relationship: regulates GO:0051630 ! acetylcholine uptake + +[Term] +id: GO:0051632 +name: negative regulation of acetylcholine uptake +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] +synonym: "down regulation of acetylcholine uptake" EXACT [] +synonym: "down-regulation of acetylcholine uptake" EXACT [] +synonym: "downregulation of acetylcholine uptake" EXACT [] +synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:0051631 ! regulation of acetylcholine uptake +is_a: GO:0051953 ! negative regulation of amine transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051630 ! acetylcholine uptake +relationship: negatively_regulates GO:0051630 ! acetylcholine uptake + +[Term] +id: GO:0051633 +name: positive regulation of acetylcholine uptake +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] +synonym: "activation of acetylcholine uptake" NARROW [] +synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] +synonym: "stimulation of acetylcholine uptake" NARROW [] +synonym: "up regulation of acetylcholine uptake" EXACT [] +synonym: "up-regulation of acetylcholine uptake" EXACT [] +synonym: "upregulation of acetylcholine uptake" EXACT [] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:0051631 ! regulation of acetylcholine uptake +is_a: GO:0051954 ! positive regulation of amine transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051630 ! acetylcholine uptake +relationship: positively_regulates GO:0051630 ! acetylcholine uptake + +[Term] +id: GO:0051634 +name: inhibition of acetylcholine uptake +namespace: biological_process +def: "Any process that prevents the activation of the directed movement of acetylcholine into a cell." [GOC:ai] +synonym: "inhibition of acetylcholine import" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051609 ! inhibition of neurotransmitter uptake +is_a: GO:0051632 ! negative regulation of acetylcholine uptake + +[Term] +id: GO:0051635 +name: obsolete bacterial cell surface binding +namespace: molecular_function +alt_id: GO:0008367 +def: "OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a bacterial cell." [GOC:ai] +comment: This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term. +synonym: "bacterial binding" EXACT [] +synonym: "bacterial cell surface binding" EXACT [] +synonym: "bacterium binding" EXACT [] +synonym: "bacterium cell surface binding" EXACT [] +synonym: "binding to bacterium" EXACT [] +is_obsolete: true +consider: GO:0003823 +consider: GO:0005102 +consider: GO:0042742 + +[Term] +id: GO:0051636 +name: obsolete Gram-negative bacterial cell surface binding +namespace: molecular_function +alt_id: GO:0008368 +def: "OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-negative bacterial cell." [GOC:ai] +comment: This term was made obsolete because it is an unnecessary grouping term and was causing confusion. +synonym: "binding to Gram-negative bacterium" EXACT [] +synonym: "Gram-negative bacterial binding" EXACT [] +synonym: "Gram-negative bacterial cell surface binding" EXACT [] +synonym: "Gram-negative bacterium binding" EXACT [] +synonym: "Gram-negative bacterium cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0003823 +consider: GO:0050829 + +[Term] +id: GO:0051637 +name: obsolete Gram-positive bacterial cell surface binding +namespace: molecular_function +alt_id: GO:0051076 +def: "OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-positive bacterium." [GOC:ai] +comment: This term was made obsolete because it is an unnecessary grouping term and was causing confusion. +synonym: "binding to Gram-positive bacterium" EXACT [] +synonym: "Gram-positive bacterial binding" EXACT [] +synonym: "Gram-positive bacterial cell surface binding" EXACT [] +synonym: "Gram-positive bacterium binding" EXACT [] +synonym: "Gram-positive bacterium cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0003823 +consider: GO:0050830 + +[Term] +id: GO:0051638 +name: barbed-end actin filament uncapping +namespace: biological_process +def: "The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] +synonym: "barbed end actin filament uncapping" EXACT [] +synonym: "barbed end F-actin uncapping" EXACT [] +synonym: "barbed-end F-actin uncapping" EXACT [] +synonym: "plus end actin filament uncapping" EXACT [] +synonym: "plus end F-actin uncapping" EXACT [] +synonym: "plus-end actin filament uncapping" EXACT [] +synonym: "plus-end F-actin uncapping" EXACT [] +is_a: GO:0051695 ! actin filament uncapping + +[Term] +id: GO:0051639 +name: actin filament network formation +namespace: biological_process +def: "The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments." [GOC:ai] +synonym: "actin gel biosynthesis" EXACT [] +synonym: "actin gel formation" EXACT [] +is_a: GO:0007015 ! actin filament organization + +[Term] +id: GO:0051640 +name: organelle localization +namespace: biological_process +def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai] +subset: goslim_pir +synonym: "establishment and maintenance of organelle localization" EXACT [] +synonym: "organelle localisation" EXACT [GOC:mah] +is_a: GO:0051641 ! cellular localization + +[Term] +id: GO:0051641 +name: cellular localization +namespace: biological_process +alt_id: GO:1902580 +def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw] +subset: goslim_pir +synonym: "cellular localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of cellular localization" EXACT [] +synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT [] +synonym: "intracellular localization" NARROW [] +synonym: "localization within cell" NARROW [] +synonym: "single organism cellular localization" EXACT [GOC:TermGenie] +synonym: "single-organism cellular localization" RELATED [] +is_a: GO:0009987 ! cellular process +is_a: GO:0051179 ! localization +created_by: jl +creation_date: 2013-12-18T14:04:32Z + +[Term] +id: GO:0051642 +name: centrosome localization +namespace: biological_process +def: "Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "centrosome localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of centrosome localization" EXACT [] +is_a: GO:0051640 ! organelle localization +is_a: GO:0061842 ! microtubule organizing center localization + +[Term] +id: GO:0051643 +name: endoplasmic reticulum localization +namespace: biological_process +def: "Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "endoplasmic reticulum localisation" EXACT [GOC:mah] +synonym: "ER localization" EXACT [GOC:dph] +synonym: "establishment and maintenance of ER localization" EXACT [] +is_a: GO:0051640 ! organelle localization +relationship: part_of GO:0007029 ! endoplasmic reticulum organization + +[Term] +id: GO:0051644 +name: plastid localization +namespace: biological_process +def: "Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "establishment and maintenance of plastid localization" EXACT [] +synonym: "plastid localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 + +[Term] +id: GO:0051645 +name: Golgi localization +namespace: biological_process +def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "establishment and maintenance of Golgi localization" EXACT [] +synonym: "Golgi apparatus localization" EXACT [] +synonym: "Golgi body localization" EXACT [] +synonym: "Golgi localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051646 +name: mitochondrion localization +namespace: biological_process +def: "Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "establishment and maintenance of mitochondria localization" EXACT [] +synonym: "establishment and maintenance of mitochondrion localization" EXACT [] +synonym: "localization of mitochondria" EXACT [] +synonym: "localization of mitochondrion" EXACT [] +synonym: "mitochondria localization" EXACT [] +synonym: "mitochondrial localization" EXACT [] +synonym: "mitochondrion localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051647 +name: nucleus localization +namespace: biological_process +def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "cell nucleus localization" EXACT [] +synonym: "establishment and maintenance of nucleus localization" EXACT [] +synonym: "localization of nucleus" EXACT [] +synonym: "nucleus localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051648 +name: vesicle localization +namespace: biological_process +def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai] +synonym: "cytoplasmic vesicle localization" EXACT [] +synonym: "establishment and maintenance of vesicle localization" EXACT [] +synonym: "vesicle localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051649 +name: establishment of localization in cell +namespace: biological_process +def: "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] +synonym: "establishment of cellular localization" RELATED [GOC:dph, GOC:tb] +synonym: "establishment of intracellular localization" NARROW [] +synonym: "establishment of localisation in cell" EXACT [GOC:mah] +synonym: "establishment of localization within cell" NARROW [] +synonym: "positioning within cell" NARROW [] +is_a: GO:0051234 ! establishment of localization +relationship: part_of GO:0051641 ! cellular localization + +[Term] +id: GO:0051650 +name: establishment of vesicle localization +namespace: biological_process +def: "The directed movement of a vesicle to a specific location." [GOC:ai] +subset: goslim_aspergillus +synonym: "establishment of vesicle localisation" EXACT [GOC:mah] +is_a: GO:0051648 ! vesicle localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051651 +name: maintenance of location in cell +namespace: biological_process +def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." [GOC:ai] +synonym: "cellular retention" NARROW [] +synonym: "cellular sequestering" NARROW [] +synonym: "cellular storage" NARROW [] +synonym: "intracellular retention" NARROW [] +synonym: "intracellular sequestering" NARROW [] +synonym: "intracellular storage" NARROW [] +synonym: "maintenance of cellular localization" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of intracellular localization" NARROW [] +synonym: "maintenance of localization in cell" RELATED [GOC:dph, GOC:tb] +synonym: "maintenance of localization within cell" NARROW [] +synonym: "retention within cell" NARROW [] +synonym: "sequestering within cell" NARROW [] +synonym: "storage within cell" NARROW [] +is_a: GO:0009987 ! cellular process +is_a: GO:0051235 ! maintenance of location +relationship: part_of GO:0051641 ! cellular localization + +[Term] +id: GO:0051652 +name: maintenance of chromosome location +namespace: biological_process +def: "Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of chromosome localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0050000 ! chromosome localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051653 +name: spindle localization +namespace: biological_process +def: "Any process in which is the spindle is transported to, and/or maintained in, a specific location." [GOC:ai] +synonym: "establishment and maintenance of spindle localization" EXACT [] +synonym: "spindle localisation" EXACT [GOC:mah] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051654 +name: establishment of mitochondrion localization +namespace: biological_process +def: "The directed movement of the mitochondrion to a specific location." [GOC:ai] +synonym: "establishment of mitochondria localization" EXACT [] +synonym: "establishment of mitochondrion localisation" EXACT [GOC:mah] +synonym: "mitochondria positioning" EXACT [] +synonym: "mitochondrial migration" EXACT [] +synonym: "mitochondrion positioning" EXACT [] +is_a: GO:0051646 ! mitochondrion localization +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051655 +name: maintenance of vesicle location +namespace: biological_process +def: "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of vesicle localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051648 ! vesicle localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051656 +name: establishment of organelle localization +namespace: biological_process +def: "The directed movement of an organelle to a specific location." [GOC:ai] +synonym: "establishment of organelle localisation" EXACT [GOC:mah] +is_a: GO:0051234 ! establishment of localization +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0051657 +name: maintenance of organelle location +namespace: biological_process +def: "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of organelle localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0051640 ! organelle localization + +[Term] +id: GO:0051658 +name: maintenance of nucleus location +namespace: biological_process +def: "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of cell nucleus location" EXACT [] +synonym: "maintenance of nucleus localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051647 ! nucleus localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051659 +name: maintenance of mitochondrion location +namespace: biological_process +def: "Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of mitochondria localization" EXACT [] +synonym: "maintenance of mitochondrion localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051646 ! mitochondrion localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051660 +name: establishment of centrosome localization +namespace: biological_process +def: "The directed movement of the centrosome to a specific location." [GOC:ai] +synonym: "centrosome positioning" EXACT [] +synonym: "establishment of centrosome localisation" EXACT [GOC:mah] +is_a: GO:0051642 ! centrosome localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051661 +name: maintenance of centrosome location +namespace: biological_process +def: "Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of centrosome localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051642 ! centrosome localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051663 +name: oocyte nucleus localization involved in oocyte dorsal/ventral axis specification +namespace: biological_process +alt_id: GO:0051662 +def: "The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte." [GOC:ai, GOC:dph, GOC:mtg_sensu, GOC:tb] +synonym: "establishment and maintenance of oocyte nucleus localization during oocyte axis determination" EXACT [] +synonym: "oocyte axis determination, oocyte nucleus localization" EXACT [] +synonym: "oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification" EXACT [GOC:mah] +synonym: "oocyte nucleus localization during oocyte axis determination" RELATED [GOC:dph, GOC:tb] +synonym: "oocyte nucleus localization involved in oocyte dorsal-ventral axis specification" EXACT [GOC:mah] +synonym: "oocyte nucleus localization involved in oocyte dorsal/ventral axis determination" EXACT [GOC:dph, GOC:tb] +synonym: "oocyte nucleus localization involved in oocyte dorsoventral axis specification" EXACT [GOC:mah] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0051647 ! nucleus localization +intersection_of: GO:0051647 ! nucleus localization +intersection_of: part_of GO:0007310 ! oocyte dorsal/ventral axis specification +relationship: part_of GO:0007310 ! oocyte dorsal/ventral axis specification + +[Term] +id: GO:0051664 +name: nuclear pore localization +namespace: biological_process +def: "Any process in which nuclear pores are transported to, or maintained in, a specific location." [GOC:ai] +synonym: "establishment and maintenance of nuclear pore localization" EXACT [] +synonym: "nuclear pore localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization +is_a: GO:0051668 ! localization within membrane + +[Term] +id: GO:0051665 +name: membrane raft localization +namespace: biological_process +def: "Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:ai, PMID:16645198] +synonym: "establishment and maintenance of membrane raft localization" EXACT [] +synonym: "lipid raft localization" EXACT [] +synonym: "membrane raft localisation" EXACT [GOC:mah] +is_a: GO:0051668 ! localization within membrane + +[Term] +id: GO:0051666 +name: actin cortical patch localization +namespace: biological_process +def: "Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells." [GOC:mah] +synonym: "actin cortical patch localisation" EXACT [GOC:mah] +synonym: "establishment and maintenance of actin cortical patch localization" EXACT [] +is_a: GO:0051641 ! cellular localization + +[Term] +id: GO:0051667 +name: establishment of plastid localization +namespace: biological_process +def: "The directed movement of a plastid to a specific location in the cell." [GOC:ai] +synonym: "establishment of plastid localisation" EXACT [GOC:mah] +is_a: GO:0051644 ! plastid localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051668 +name: localization within membrane +namespace: biological_process +def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai] +synonym: "establishment and maintenance of localization in membrane" EXACT [] +synonym: "establishment and maintenance of position in membrane" EXACT [] +synonym: "localisation within membrane" EXACT [GOC:mah] +synonym: "localization to membrane" EXACT [] +synonym: "positioning within membrane" NARROW [] +is_a: GO:0051641 ! cellular localization +intersection_of: GO:0051179 ! localization +intersection_of: occurs_in GO:0016020 ! membrane +relationship: occurs_in GO:0016020 ! membrane + +[Term] +id: GO:0051669 +name: fructan beta-fructosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.80] +synonym: "beta-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.80] +synonym: "exo-beta-D-fructosidase activity" EXACT [] +synonym: "exo-beta-fructosidase activity" EXACT [] +synonym: "fructan b-fructosidase activity" EXACT [] +synonym: "fructan exohydrolase activity" EXACT [] +synonym: "fructanase activity" EXACT [EC:3.2.1.80] +synonym: "polysaccharide beta-fructofuranosidase activity" EXACT [] +xref: EC:3.2.1.80 +xref: MetaCyc:3.2.1.80-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0051670 +name: inulinase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin." [EC:3.2.1.7] +synonym: "2,1-beta-D-fructan fructanohydrolase activity" EXACT [] +synonym: "endo-inulinase activity" EXACT [] +synonym: "exoinulinase activity" EXACT [] +synonym: "indoinulinase activity" EXACT [] +synonym: "inulase activity" EXACT [] +xref: EC:3.2.1.7 +xref: MetaCyc:3.2.1.7-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0051671 +name: induction of autolysin activity in other organism +namespace: biological_process +def: "Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism." [GOC:ai] +synonym: "activation of autolysin activity in another organism" EXACT [] +synonym: "activation of autolysis in other organism" NARROW [] +synonym: "activation of autolytic activity in other organism" NARROW [] +synonym: "induction of autolysin activity in another organism" EXACT [GOC:bf] +synonym: "induction of autolysis in other organism" NARROW [] +synonym: "induction of autolytic activity in other organism" NARROW [] +synonym: "positive regulation of autolysin activity in another organism" BROAD [] +is_a: GO:0043946 ! positive regulation of catalytic activity in other organism involved in symbiotic interaction + +[Term] +id: GO:0051672 +name: catabolism by organism of cell wall peptidoglycan in other organism +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism." [GOC:ai] +synonym: "catabolic process of cell wall peptidoglycans of other organism" EXACT [] +synonym: "catabolism of cell wall peptidoglycans of other organism" EXACT [] +synonym: "cell wall catabolic process in other organism" NARROW [] +synonym: "cell wall catabolism in other organism" NARROW [] +synonym: "cell wall peptidoglycan catabolic process in another organism" EXACT [] +is_a: GO:0009253 ! peptidoglycan catabolic process +is_a: GO:0044041 ! multi-organism carbohydrate catabolic process +relationship: part_of GO:0009617 ! response to bacterium +relationship: part_of GO:0044278 ! cell wall disruption in other organism + +[Term] +id: GO:0051673 +name: membrane disruption in other organism +namespace: biological_process +def: "The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism." [GOC:ai] +synonym: "cytolysis, by membrane disruption, in other organism" NARROW [] +synonym: "membrane disruption in another organism" EXACT [GOC:bf] +is_a: GO:0035821 ! modulation of process of other organism + +[Term] +id: GO:0051674 +name: localization of cell +namespace: biological_process +def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai] +synonym: "cell localization" EXACT [] +synonym: "establishment and maintenance of cell localization" EXACT [] +synonym: "establishment and maintenance of localization of cell" EXACT [] +synonym: "localisation of cell" EXACT [GOC:mah] +is_a: GO:0009987 ! cellular process +is_a: GO:0051179 ! localization + +[Term] +id: GO:0051675 +name: isopullulanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose)." [EC:3.2.1.57] +synonym: "pullulan 4-glucanohydrolase (isopanose-forming) activity" EXACT [] +xref: EC:3.2.1.57 +xref: MetaCyc:3.2.1.57-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0051676 +name: pullulan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages." [PMID:15013381] +synonym: "pullulan metabolism" EXACT [] +is_a: GO:0006073 ! cellular glucan metabolic process + +[Term] +id: GO:0051677 +name: pullulan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages." [GOC:ai] +is_a: GO:0009250 ! glucan biosynthetic process +is_a: GO:0051676 ! pullulan metabolic process + +[Term] +id: GO:0051678 +name: pullulan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages." [GOC:ai] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0051676 ! pullulan metabolic process + +[Term] +id: GO:0051679 +name: 6-alpha-maltosylglucose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose." [GOC:ai, LIGAND:C03367, PubChem_Compound:439991] +synonym: "6-alpha-maltosylglucose metabolism" EXACT [] +synonym: "isopanose metabolic process" EXACT [] +synonym: "isopanose metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0044264 ! cellular polysaccharide metabolic process + +[Term] +id: GO:0051680 +name: 6-alpha-maltosylglucose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose." [GOC:ai] +synonym: "isopanose biosynthesis" EXACT [] +synonym: "isopanose biosynthetic process" EXACT [] +is_a: GO:0009312 ! oligosaccharide biosynthetic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0051679 ! 6-alpha-maltosylglucose metabolic process + +[Term] +id: GO:0051681 +name: 6-alpha-maltosylglucose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose." [GOC:ai] +synonym: "isopanose catabolic process" EXACT [] +synonym: "isopanose catabolism" EXACT [] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0051679 ! 6-alpha-maltosylglucose metabolic process + +[Term] +id: GO:0051682 +name: galactomannan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units." [GOC:ai] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0051069 ! galactomannan metabolic process + +[Term] +id: GO:0051683 +name: establishment of Golgi localization +namespace: biological_process +def: "The directed movement of the Golgi to a specific location." [GOC:ai] +synonym: "establishment of Golgi apparatus localization" EXACT [] +synonym: "establishment of Golgi body localization" EXACT [] +synonym: "establishment of Golgi localisation" EXACT [GOC:mah] +is_a: GO:0051645 ! Golgi localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051684 +name: maintenance of Golgi location +namespace: biological_process +def: "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of Golgi apparatus localization" EXACT [] +synonym: "maintenance of Golgi body localization" EXACT [] +synonym: "maintenance of Golgi localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051645 ! Golgi localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051685 +name: maintenance of ER location +namespace: biological_process +def: "Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of endoplasmic reticulum localization" EXACT [] +synonym: "maintenance of ER localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051643 ! endoplasmic reticulum localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051686 +name: establishment of ER localization +namespace: biological_process +def: "The directed movement of the endoplasmic reticulum to a specific location." [GOC:ai] +synonym: "establishment of endoplasmic reticulum localization" EXACT [] +synonym: "establishment of ER localisation" EXACT [GOC:mah] +is_a: GO:0051643 ! endoplasmic reticulum localization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0051656 ! establishment of organelle localization + +[Term] +id: GO:0051687 +name: maintenance of spindle location +namespace: biological_process +def: "Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of spindle localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051653 ! spindle localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051688 +name: maintenance of plastid location +namespace: biological_process +def: "Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of plastid localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051644 ! plastid localization +is_a: GO:0051657 ! maintenance of organelle location + +[Term] +id: GO:0051691 +name: cellular oligosaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells." [GOC:ai] +synonym: "cellular oligosaccharide metabolism" EXACT [] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0044262 ! cellular carbohydrate metabolic process + +[Term] +id: GO:0051692 +name: cellular oligosaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells." [GOC:ai] +synonym: "cellular oligosaccharide breakdown" EXACT [] +synonym: "cellular oligosaccharide catabolism" EXACT [] +synonym: "cellular oligosaccharide degradation" EXACT [] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:0044275 ! cellular carbohydrate catabolic process +is_a: GO:0051691 ! cellular oligosaccharide metabolic process + +[Term] +id: GO:0051693 +name: actin filament capping +namespace: biological_process +def: "The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] +synonym: "actin capping activity" RELATED [] +synonym: "F-actin capping activity" RELATED [] +is_a: GO:0030835 ! negative regulation of actin filament depolymerization +is_a: GO:0030837 ! negative regulation of actin filament polymerization + +[Term] +id: GO:0051694 +name: pointed-end actin filament capping +namespace: biological_process +def: "The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] +synonym: "minus-end actin filament capping activity" EXACT [] +synonym: "minus-end F-actin capping activity" EXACT [] +synonym: "pointed-end actin capping activity" EXACT [] +synonym: "pointed-end F-actin capping activity" EXACT [] +is_a: GO:0051693 ! actin filament capping + +[Term] +id: GO:0051695 +name: actin filament uncapping +namespace: biological_process +def: "The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] +synonym: "F-actin uncapping" EXACT [] +is_a: GO:0030836 ! positive regulation of actin filament depolymerization + +[Term] +id: GO:0051696 +name: pointed-end actin filament uncapping +namespace: biological_process +def: "The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] +synonym: "minus end actin filament uncapping" EXACT [] +synonym: "minus end F-actin uncapping" EXACT [] +synonym: "minus-end actin filament uncapping" EXACT [] +synonym: "minus-end F-actin uncapping" EXACT [] +synonym: "pointed end actin filament uncapping" EXACT [] +synonym: "pointed end F-actin uncapping" EXACT [] +synonym: "pointed-end F-actin uncapping" EXACT [] +is_a: GO:0051695 ! actin filament uncapping + +[Term] +id: GO:0051697 +name: protein delipidation +namespace: biological_process +def: "The breakage of covalent bonds to detach lipid groups from a protein." [GOC:ai] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0051698 +name: saccharopine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2." [PMID:16233628] +synonym: "SAX activity" BROAD [] +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0051699 +name: proline oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2." [MetaCyc:RXN-821] +xref: MetaCyc:RXN-821 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0051700 +name: fructosyl-amino acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2." [PMID:16233628] +synonym: "FAOD activity" EXACT [] +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0051701 +name: interaction with host +namespace: biological_process +def: "An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism." [GOC:cc] +is_a: GO:0044403 ! symbiotic process + +[Term] +id: GO:0051702 +name: interaction with symbiont +namespace: biological_process +def: "An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism." [GOC:cc] +is_a: GO:0044419 ! interspecies interaction between organisms +relationship: part_of GO:0044403 ! symbiotic process + +[Term] +id: GO:0051703 +name: intraspecies interaction between organisms +namespace: biological_process +def: "Any process in which an organism has an effect on an organism of the same species." [GOC:ai] +subset: goslim_pir +synonym: "intraspecies interaction with other organisms" EXACT [] +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0051704 +name: multi-organism process +namespace: biological_process +alt_id: GO:0051706 +def: "A biological process which involves another organism of the same or different species." [GOC:jl] +subset: gocheck_do_not_annotate +subset: goslim_pir +synonym: "interaction between organisms" EXACT [] +synonym: "physiological interaction between organisms" EXACT [] +synonym: "physiological interaction with other organism" EXACT [] +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0051705 +name: obsolete multi-organism behavior +namespace: biological_process +def: "OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species." [GOC:ai] +comment: This term was obsoleted because it was an unnecessary grouping term. +subset: goslim_pir +synonym: "behavioral interaction between organisms" EXACT [] +synonym: "behavioral interaction with other organism" EXACT [] +synonym: "behavioral signaling" NARROW [] +synonym: "behavioral signalling" NARROW [GOC:mah] +synonym: "behavioural interaction between organisms" EXACT [] +synonym: "behavioural interaction with other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18810 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051707 +name: response to other organism +namespace: biological_process +alt_id: GO:0009613 +alt_id: GO:0042828 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai] +is_a: GO:0043207 ! response to external biotic stimulus +is_a: GO:0044419 ! interspecies interaction between organisms + +[Term] +id: GO:0051709 +name: regulation of killing of cells of other organism +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism." [GOC:ai] +synonym: "regulation of killing of cells of another organism" EXACT [GOC:bf] +is_a: GO:0031341 ! regulation of cell killing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031640 ! killing of cells of other organism +relationship: regulates GO:0031640 ! killing of cells of other organism + +[Term] +id: GO:0051710 +name: regulation of cytolysis in other organism +namespace: biological_process +alt_id: GO:0001902 +def: "Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism." [GOC:ai] +synonym: "regulation of cytolysis of cells of another organism" EXACT [GOC:bf] +synonym: "regulation of cytolysis of cells of another, non-host, organism" NARROW [] +is_a: GO:0042268 ! regulation of cytolysis +is_a: GO:0051709 ! regulation of killing of cells of other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051715 ! cytolysis in other organism +relationship: regulates GO:0051715 ! cytolysis in other organism + +[Term] +id: GO:0051711 +name: negative regulation of killing of cells of other organism +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism." [GOC:ai] +synonym: "down regulation of killing of cells of another organism" EXACT [] +synonym: "down-regulation of killing of cells of another organism" EXACT [] +synonym: "downregulation of killing of cells of another organism" EXACT [] +synonym: "inhibition of killing of cells of another organism" NARROW [] +synonym: "negative regulation of killing of cells of another organism" EXACT [GOC:bf] +is_a: GO:0031342 ! negative regulation of cell killing +is_a: GO:0051709 ! regulation of killing of cells of other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031640 ! killing of cells of other organism +relationship: negatively_regulates GO:0031640 ! killing of cells of other organism + +[Term] +id: GO:0051712 +name: positive regulation of killing of cells of other organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism." [GOC:ai] +synonym: "activation of killing of cells of another organism" NARROW [] +synonym: "stimulation of killing of cells of another organism" NARROW [] +synonym: "up regulation of killing of cells of another organism" EXACT [] +synonym: "up-regulation of killing of cells of another organism" EXACT [] +synonym: "upregulation of killing of cells of another organism" EXACT [] +is_a: GO:0031343 ! positive regulation of cell killing +is_a: GO:0051709 ! regulation of killing of cells of other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031640 ! killing of cells of other organism +relationship: positively_regulates GO:0031640 ! killing of cells of other organism + +[Term] +id: GO:0051713 +name: negative regulation of cytolysis in other organism +namespace: biological_process +alt_id: GO:0001903 +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism." [GOC:ai] +synonym: "down regulation of cytolysis of cells of another organism" EXACT [] +synonym: "down-regulation of cytolysis of cells of another organism" EXACT [] +synonym: "downregulation of cytolysis of cells of another organism" EXACT [] +synonym: "inhibition of cytolysis of cells of another organism" NARROW [] +synonym: "negative regulation of cytolysis of cells of another organism" EXACT [GOC:bf] +synonym: "negative regulation of cytolysis of cells of another, non-host, organism" NARROW [] +is_a: GO:0045918 ! negative regulation of cytolysis +is_a: GO:0051710 ! regulation of cytolysis in other organism +is_a: GO:0051711 ! negative regulation of killing of cells of other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051715 ! cytolysis in other organism +relationship: negatively_regulates GO:0051715 ! cytolysis in other organism + +[Term] +id: GO:0051714 +name: positive regulation of cytolysis in other organism +namespace: biological_process +alt_id: GO:0001904 +def: "Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism." [GOC:ai] +synonym: "activation of cytolysis of cells of another organism" NARROW [] +synonym: "positive regulation of cytolysis of cells of another organism" EXACT [GOC:bf] +synonym: "positive regulation of cytolysis of cells of another, non-host, organism" NARROW [] +synonym: "stimulation of cytolysis of cells of another organism" NARROW [] +synonym: "up regulation of cytolysis of cells of another organism" EXACT [] +synonym: "up-regulation of cytolysis of cells of another organism" EXACT [] +synonym: "upregulation of cytolysis of cells of another organism" EXACT [] +is_a: GO:0045919 ! positive regulation of cytolysis +is_a: GO:0051710 ! regulation of cytolysis in other organism +is_a: GO:0051712 ! positive regulation of killing of cells of other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051715 ! cytolysis in other organism +relationship: positively_regulates GO:0051715 ! cytolysis in other organism + +[Term] +id: GO:0051715 +name: cytolysis in other organism +namespace: biological_process +alt_id: GO:0001901 +def: "The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm." [GOC:ai] +synonym: "cytolysis of cells of another organism" EXACT [GOC:bf] +synonym: "cytolysis of cells of another, non-host, organism" NARROW [] +synonym: "cytolysis of cells of competing organism" NARROW [] +is_a: GO:0019835 ! cytolysis +is_a: GO:0031640 ! killing of cells of other organism + +[Term] +id: GO:0051716 +name: cellular response to stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0009987 ! cellular process +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0051717 +name: inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate." [GOC:bf, MetaCyc:3.1.3.62-RXN] +synonym: "inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity" EXACT [EC:2.7.1.-] +synonym: "inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity" EXACT [EC:2.7.1.-] +synonym: "inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity" EXACT [EC:2.7.1.-] +xref: MetaCyc:3.1.3.62-RXN +xref: Reactome:R-HSA-1855200 "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen" +xref: Reactome:R-HSA-1855205 "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol" +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity + +[Term] +id: GO:0051718 +name: DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA)." [EC:2.1.1.37, PMID:15689527] +synonym: "HpaII methylase" NARROW [EC:2.1.1.37] +synonym: "HpaII' methylase" NARROW [EC:2.1.1.37] +synonym: "M.BsuRIa" NARROW [EC:2.1.1.37] +synonym: "M.BsuRIb" NARROW [EC:2.1.1.37] +xref: Reactome:R-HSA-5334151 "DNMT1 methylates cytosine in hemimethylated DNA" +is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity + +[Term] +id: GO:0051719 +name: DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN." [EC:2.1.1.37, PMID:15689527] +xref: Reactome:R-HSA-5334097 "DNMT3B:DNMT3L methylates cytosine in DNA" +xref: Reactome:R-HSA-5334152 "DNMT3A:DNMT3L methylates cytosine in DNA" +is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity + +[Term] +id: GO:0051720 +name: DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG." [EC:2.1.1.37, PMID:15689527] +is_a: GO:0003886 ! DNA (cytosine-5-)-methyltransferase activity + +[Term] +id: GO:0051721 +name: protein phosphatase 2A binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme protein phosphatase 2A." [GOC:ai] +synonym: "protein phosphatase 2 binding" RELATED [GOC:rl] +is_a: GO:0019903 ! protein phosphatase binding + +[Term] +id: GO:0051722 +name: protein C-terminal methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol." [PMID:10318862, PMID:8650216] +synonym: "protein phosphatase methylesterase activity" NARROW [] +xref: Reactome:R-HSA-8856951 "PP2A demethylation by PPME1" +is_a: GO:0051723 ! protein methylesterase activity + +[Term] +id: GO:0051723 +name: protein methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol." [GOC:ai] +synonym: "PME activity" EXACT [EC:2.7.1.-] +synonym: "protein carboxyl methylesterase activity" EXACT [EC:2.7.1.-] +synonym: "protein carboxylic ester hydrolase activity" EXACT [] +synonym: "protein methyl-esterase activity" EXACT [EC:2.7.1.-] +xref: Reactome:R-HSA-5367022 "DPH7 hydrolyzes a methyl group on Me-diphthine EEF2" +is_a: GO:0052689 ! carboxylic ester hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0051724 +name: NAD transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901368 +def: "Enables the transfer of NAD from one side of a membrane to the other." [GOC:TermGenie] +comment: NAD carrier +synonym: "NAD (oxidized) transporter activity" EXACT [] +synonym: "NAD (reduced) transporter activity" EXACT [] +synonym: "NAD transporter activity" RELATED [] +synonym: "NAD+ transporter activity" EXACT [] +synonym: "NADH transporter activity" EXACT [] +synonym: "nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] +synonym: "oxidized NAD transporter activity" EXACT [] +synonym: "oxidized nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] +synonym: "reduced NAD transporter activity" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] +is_a: GO:0015215 ! nucleotide transmembrane transporter activity +is_a: GO:0051185 ! coenzyme transmembrane transporter activity +relationship: part_of GO:0035352 ! NAD transmembrane transport +created_by: jl +creation_date: 2012-09-19T13:21:08Z + +[Term] +id: GO:0051725 +name: protein de-ADP-ribosylation +namespace: biological_process +def: "The process of removing one or more ADP-ribose residues from a protein." [GOC:ai] +synonym: "poly(ADP-ribose) removal from protein" EXACT [] +synonym: "protein amino acid de-ADP-ribosylation" EXACT [GOC:bf] +synonym: "protein poly(ADP-ribose) catabolic process" EXACT [] +synonym: "protein poly(ADP-ribose) catabolism" EXACT [] +synonym: "protein poly(ADP-ribose) degradation" EXACT [] +synonym: "protein poly(ADP-ribose) hydrolysis" EXACT [] +synonym: "removal of ADP-ribose from protein" EXACT [] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0051726 +name: regulation of cell cycle +namespace: biological_process +alt_id: GO:0000074 +def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_yeast +synonym: "cell cycle modulation" EXACT [] +synonym: "cell cycle regulation" EXACT [] +synonym: "cell cycle regulator" RELATED [] +synonym: "control of cell cycle progression" EXACT [] +synonym: "modulation of cell cycle progression" EXACT [] +synonym: "regulation of cell cycle progression" EXACT [] +synonym: "regulation of progression through cell cycle" EXACT [] +synonym: "tumor suppressor" RELATED [] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007049 ! cell cycle +relationship: regulates GO:0007049 ! cell cycle + +[Term] +id: GO:0051727 +name: obsolete cell cycle switching, meiotic to mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division." [GOC:ai, GOC:mtg_cell_cycle] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "cell cycle switching, meiosis to mitosis" NARROW [] +synonym: "cell cycle switching, meiotic to mitotic cell cycle" EXACT [] +synonym: "conversion to mitosis" NARROW [] +synonym: "conversion to mitotic cell cycle" EXACT [] +synonym: "entry into mitosis" NARROW [] +synonym: "entry into mitotic cell cycle" EXACT [] +synonym: "initiation of mitosis" NARROW [] +synonym: "initiation of mitotic cell cycle" EXACT [] +synonym: "mitotic entry" NARROW [] +is_obsolete: true + +[Term] +id: GO:0051728 +name: cell cycle switching, mitotic to meiotic cell cycle +namespace: biological_process +alt_id: GO:0042061 +def: "The process in which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai, GOC:mtg_cell_cycle] +synonym: "cell cycle switching, mitosis to meiosis" NARROW [] +synonym: "conversion to meiosis" NARROW [] +synonym: "conversion to meiotic cell cycle" EXACT [] +synonym: "entry into meiosis" NARROW [] +synonym: "entry into meiotic cell cycle" EXACT [] +synonym: "initiation of meiosis" NARROW [] +synonym: "initiation of meiotic cell cycle" EXACT [] +synonym: "meiotic entry" NARROW [] +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0060184 ! cell cycle switching + +[Term] +id: GO:0051729 +name: germline cell cycle switching, mitotic to meiotic cell cycle +namespace: biological_process +def: "The process in which a germline cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai] +synonym: "germline cell cycle switching, mitosis to meiosis" NARROW [] +synonym: "germline conversion to meiosis" NARROW [] +synonym: "germline conversion to meiotic cell cycle" EXACT [] +synonym: "germline entry into meiosis" NARROW [] +synonym: "germline entry into meiotic cell cycle" EXACT [] +synonym: "germline initiation of meiosis" NARROW [] +synonym: "germline initiation of meiotic cell cycle" EXACT [] +synonym: "germline meiotic entry" NARROW [] +is_a: GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle + +[Term] +id: GO:0051730 +name: GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA." [EC:2.7.1.78, PMID:8428918] +synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] +synonym: "GTP-dependent polyribonucleotide kinase activity" EXACT [] +synonym: "GTP-dependent RNA 5'-hydroxyl-kinase activity" EXACT [] +synonym: "GTP-dependent RNA kinase activity" EXACT [] +synonym: "GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity" EXACT [] +is_a: GO:0051732 ! polyribonucleotide kinase activity +is_a: GO:0051735 ! GTP-dependent polynucleotide kinase activity + +[Term] +id: GO:0051731 +name: polynucleotide 5'-hydroxyl-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [GOC:curators] +synonym: "5'-dephosphopolynucleotide kinase activity" EXACT [] +synonym: "5'-hydroxyl polynucleotide kinase activity" EXACT [] +synonym: "PNK" RELATED [] +synonym: "polynucleotide 5'-hydroxy-kinase activity" EXACT [] +synonym: "polynucleotide 5'-hydroxyl kinase (phosphorylating) activity" EXACT [] +synonym: "polynucleotide kinase activity" BROAD [] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0019205 ! nucleobase-containing compound kinase activity + +[Term] +id: GO:0051732 +name: polyribonucleotide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA." [GOC:curators] +synonym: "5'-hydroxyl polyribonucleotide kinase activity" EXACT [] +synonym: "5'-hydroxyl RNA kinase activity" EXACT [] +synonym: "RNA 5'-hydroxyl kinase activity" EXACT [] +synonym: "RNA kinase activity" EXACT [] +is_a: GO:0051731 ! polynucleotide 5'-hydroxyl-kinase activity + +[Term] +id: GO:0051733 +name: polydeoxyribonucleotide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA." [GOC:curators] +synonym: "DNA 5'-hydroxyl kinase activity" EXACT [] +synonym: "DNA kinase activity" EXACT [] +is_a: GO:0051731 ! polynucleotide 5'-hydroxyl-kinase activity + +[Term] +id: GO:0051734 +name: ATP-dependent polynucleotide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [EC:2.7.1.78] +synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" EXACT [] +synonym: "ATP:5'-dephosphopolynucleotide 5'-phosphatase activity" EXACT [EC:2.7.1.78] +synonym: "ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity" EXACT [] +xref: EC:2.7.1.78 +is_a: GO:0051731 ! polynucleotide 5'-hydroxyl-kinase activity + +[Term] +id: GO:0051735 +name: GTP-dependent polynucleotide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [GOC:curators] +synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" EXACT [] +synonym: "GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity" EXACT [] +is_a: GO:0051731 ! polynucleotide 5'-hydroxyl-kinase activity + +[Term] +id: GO:0051736 +name: ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA." [EC:2.7.1.78] +synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] +synonym: "ATP-dependent polyribonucleotide kinase activity" EXACT [] +synonym: "ATP-dependent RNA 5'-hydroxyl-kinase activity" EXACT [] +synonym: "ATP-dependent RNA kinase activity" EXACT [] +synonym: "ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity" EXACT [] +is_a: GO:0051732 ! polyribonucleotide kinase activity +is_a: GO:0051734 ! ATP-dependent polynucleotide kinase activity + +[Term] +id: GO:0051737 +name: GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA." [EC:2.7.1.78, PMID:8428918] +synonym: "GTP-dependent DNA 5'-hydroxyl-kinase activity" EXACT [] +synonym: "GTP-dependent DNA kinase activity" EXACT [] +synonym: "GTP-dependent polydeoxyribonucleotide kinase activity" EXACT [] +synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] +synonym: "GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity" EXACT [] +is_a: GO:0051733 ! polydeoxyribonucleotide kinase activity +is_a: GO:0051735 ! GTP-dependent polynucleotide kinase activity + +[Term] +id: GO:0051738 +name: xanthophyll binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen." [ISBN:0122146743] +is_a: GO:0019840 ! isoprenoid binding +is_a: GO:0031409 ! pigment binding + +[Term] +id: GO:0051740 +name: ethylene binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator." [GOC:ai] +synonym: "ethene binding" EXACT [] +is_a: GO:0042562 ! hormone binding +is_a: GO:0072328 ! alkene binding + +[Term] +id: GO:0051741 +name: 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine." [MetaCyc:RXN-2542] +synonym: "MPBQ methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-2542 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0051742 +name: 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine." [MetaCyc:RXN-2762] +synonym: "MSBQ methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-2762 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0051743 +name: red chlorophyll catabolite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence." [PMID:10743659] +synonym: "RCC reductase activity" EXACT [] +xref: MetaCyc:RXN-7741 +is_a: GO:0016636 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0051744 +name: 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+." [MetaCyc:RXN1F-72] +xref: MetaCyc:RXN1F-72 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0051745 +name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate." [EC:1.17.1.2] +synonym: "4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity" EXACT [EC:1.17.1.2] +synonym: "isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity" EXACT [] +xref: EC:1.17.1.2 +xref: MetaCyc:ISPH2-RXN +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0051746 +name: thalianol synthase activity +namespace: molecular_function +def: "Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol)." [PMID:15125655] +xref: EC:5.4.99.31 +xref: RHEA:26163 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0051747 +name: cytosine C-5 DNA demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA." [PMID:10050851] +synonym: "DNA demethylase activity" BROAD [PMID:10050851] +synonym: "DNA methyltransferase activity acting on cytosine C-5" EXACT [] +synonym: "hydrolytic DNA demethylase activity" BROAD [] +is_a: GO:0016787 ! hydrolase activity +is_a: GO:0035514 ! DNA demethylase activity + +[Term] +id: GO:0051748 +name: UTP-monosaccharide-1-phosphate uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide." [EC:2.7.7.64, PMID:15326166] +synonym: "PsUSP" RELATED [EC:2.7.7.64] +synonym: "UDP-monosaccharide diphosphorylase activity" EXACT [] +synonym: "UDP-monosaccharide pyrophosphorylase activity" EXACT [] +synonym: "UDP-sugar pyrophosphorylase activity" EXACT [EC:2.7.7.64] +synonym: "USP" RELATED [EC:2.7.7.64] +xref: EC:2.7.7.64 +xref: MetaCyc:2.7.7.64-RXN +is_a: GO:0070569 ! uridylyltransferase activity + +[Term] +id: GO:0051749 +name: indole acetic acid carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine." [PMID:16169896] +synonym: "IAA carboxyl methyltransferase activity" EXACT [] +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0051750 +name: delta3,5-delta2,4-dienoyl-CoA isomerase activity +namespace: molecular_function +alt_id: GO:0008416 +def: "Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA." [PMID:11278886, PMID:16040662] +synonym: "delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity" EXACT [] +synonym: "delta5-delta2,4-dienoyl-CoA isomerase activity" RELATED [] +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0051751 +name: alpha-1,4-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage." [PMID:15772281] +is_a: GO:0000030 ! mannosyltransferase activity + +[Term] +id: GO:0051752 +name: phosphoglucan, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate." [EC:2.7.9.5, PMID:15618411] +synonym: "ATP:phospho-alpha-glucan, water phosphotransferase activity" EXACT [EC:2.7.9.5] +synonym: "OK1" RELATED [EC:2.7.9.5] +synonym: "PWD" RELATED [EC:2.7.9.5] +xref: EC:2.7.9.5 +xref: MetaCyc:2.7.9.5-RXN +is_a: GO:0016301 ! kinase activity +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0051753 +name: mannan synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan." [PMID:14726589] +synonym: "galactomannan beta-1,4-mannosyltransferase activity" NARROW [] +synonym: "mannan beta-1,4-mannosyltransferase activity" EXACT [] +is_a: GO:0019187 ! beta-1,4-mannosyltransferase activity + +[Term] +id: GO:0051754 +name: meiotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "The cell cycle process in which centromeres of sister chromatids are joined during meiosis." [PMID:14730319, PMID:16325576] +synonym: "centromeric meiotic sister chromatin cohesion" EXACT [GOC:bf] +synonym: "meiotic sister chromatid cohesion at centromere" EXACT [] +synonym: "sister chromatid cohesion at centromere at meiosis I" EXACT [] +is_a: GO:0051177 ! meiotic sister chromatid cohesion +is_a: GO:0070601 ! centromeric sister chromatid cohesion + +[Term] +id: GO:0051755 +name: meiotic sister chromatid arm separation +namespace: biological_process +def: "The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis." [GOC:ai] +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007127 ! meiosis I +relationship: part_of GO:0051757 ! meiotic sister chromatid separation + +[Term] +id: GO:0051756 +name: meiotic sister chromatid centromere separation +namespace: biological_process +def: "The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576] +is_a: GO:0034510 ! centromere separation +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0045144 ! meiotic sister chromatid segregation +relationship: part_of GO:0051757 ! meiotic sister chromatid separation + +[Term] +id: GO:0051757 +name: meiotic sister chromatid separation +namespace: biological_process +def: "The process in which sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576] +synonym: "meiotic sister chromatid resolution" EXACT [GOC:mah] +is_a: GO:0051307 ! meiotic chromosome separation + +[Term] +id: GO:0051758 +name: homologous chromosome movement towards spindle pole in meiosis I anaphase +namespace: biological_process +def: "The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase." [GOC:ai] +synonym: "homologous chromosome movement towards spindle pole during meiosis I" RELATED [GOC:dph, GOC:tb] +synonym: "meiosis I, homologous chromosome movement towards spindle pole" EXACT [] +is_a: GO:0016344 ! meiotic chromosome movement towards spindle pole +relationship: part_of GO:0045143 ! homologous chromosome segregation + +[Term] +id: GO:0051759 +name: sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation +namespace: biological_process +def: "The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II." [GOC:ai] +synonym: "meiosis II, sister chromosome movement towards spindle pole" EXACT [] +synonym: "sister chromosome movement towards spindle pole during meiosis II" RELATED [GOC:dph, GOC:tb] +is_a: GO:0016344 ! meiotic chromosome movement towards spindle pole +relationship: part_of GO:0045144 ! meiotic sister chromatid segregation + +[Term] +id: GO:0051760 +name: meiotic sister chromatid cohesion, arms +namespace: biological_process +def: "The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis." [PMID:14730319, PMID:16325576] +synonym: "meiotic sister chromatid cohesion along arms" EXACT [] +synonym: "sister chromatid cohesion along arms at meiosis I" EXACT [] +is_a: GO:0051177 ! meiotic sister chromatid cohesion + +[Term] +id: GO:0051761 +name: sesquiterpene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] +synonym: "sesquiterpene metabolism" EXACT [] +is_a: GO:0042214 ! terpene metabolic process + +[Term] +id: GO:0051762 +name: sesquiterpene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] +is_a: GO:0046246 ! terpene biosynthetic process +is_a: GO:0051761 ! sesquiterpene metabolic process + +[Term] +id: GO:0051763 +name: sesquiterpene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene." [GOC:ai] +is_a: GO:0046247 ! terpene catabolic process +is_a: GO:0051761 ! sesquiterpene metabolic process + +[Term] +id: GO:0051764 +name: actin crosslink formation +namespace: biological_process +def: "The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes." [GOC:ai] +comment: See also the molecular function term 'protein binding, bridging ; GO:0030674'. +synonym: "actin bundling" RELATED [] +synonym: "actin crosslinking" EXACT [] +synonym: "bridging actin filaments" NARROW [] +synonym: "formation of actin crosslink" EXACT [] +is_a: GO:0007015 ! actin filament organization + +[Term] +id: GO:0051765 +name: inositol tetrakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP." [GOC:ai] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0051766 +name: inositol trisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP." [GOC:ai] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0051767 +name: nitric-oxide synthase biosynthetic process +namespace: biological_process +alt_id: GO:0051768 +def: "The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+." [EC:1.14.13.39, GOC:ai] +synonym: "brain nitric-oxide synthase biosynthetic process" NARROW [GOC:bf] +synonym: "endothelial nitric-oxide synthase biosynthetic process" NARROW [GOC:bf] +synonym: "inducible nitric-oxide synthase biosynthetic process" NARROW [GOC:bf] +synonym: "nitric-oxide synthase (type 2) biosynthesis" NARROW [] +synonym: "nitric-oxide synthase (type 2) biosynthetic process" NARROW [] +synonym: "nitric-oxide synthase (type II) biosynthesis" NARROW [] +synonym: "nitric-oxide synthase (type II) biosynthetic process" NARROW [] +synonym: "nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "nitric-oxide synthase-1 biosynthetic process" NARROW [GOC:bf] +synonym: "nitric-oxide synthase-2 biosynthetic process" NARROW [GOC:bf] +synonym: "nitric-oxide synthase-3 biosynthetic process" NARROW [GOC:bf] +synonym: "NO synthase biosynthesis" EXACT [] +synonym: "NO synthase biosynthetic process" EXACT [] +synonym: "NOS biosynthesis" EXACT [] +synonym: "NOS biosynthetic process" EXACT [] +synonym: "NOS1 biosynthesis" NARROW [GOC:bf] +synonym: "NOS2 biosynthesis" NARROW [GOC:bf] +synonym: "NOS2 synthase biosynthesis" NARROW [] +synonym: "NOS2 synthase biosynthetic process" NARROW [] +synonym: "NOS3 biosynthesis" NARROW [GOC:bf] +is_a: GO:0009059 ! macromolecule biosynthetic process +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0051769 +name: regulation of nitric-oxide synthase biosynthetic process +namespace: biological_process +alt_id: GO:0051772 +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme." [GOC:ai] +synonym: "regulation of nitric-oxide synthase (type 2) biosynthesis" NARROW [] +synonym: "regulation of nitric-oxide synthase (type 2) biosynthetic process" NARROW [] +synonym: "regulation of nitric-oxide synthase (type II) biosynthesis" NARROW [] +synonym: "regulation of nitric-oxide synthase (type II) biosynthetic process" NARROW [] +synonym: "regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "regulation of NO synthase biosynthesis" EXACT [] +synonym: "regulation of NO synthase biosynthetic process" EXACT [] +synonym: "regulation of NOS biosynthesis" EXACT [] +synonym: "regulation of NOS biosynthetic process" EXACT [] +synonym: "regulation of NOS2 synthase biosynthesis" NARROW [] +synonym: "regulation of NOS2 synthase biosynthetic process" NARROW [] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051767 ! nitric-oxide synthase biosynthetic process +relationship: regulates GO:0051767 ! nitric-oxide synthase biosynthetic process + +[Term] +id: GO:0051770 +name: positive regulation of nitric-oxide synthase biosynthetic process +namespace: biological_process +alt_id: GO:0051773 +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme." [GOC:ai] +synonym: "activation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "activation of nitric-oxide synthase biosynthetic process" NARROW [] +synonym: "positive regulation of nitric-oxide synthase (type 2) biosynthesis" NARROW [] +synonym: "positive regulation of nitric-oxide synthase (type 2) biosynthetic process" NARROW [] +synonym: "positive regulation of nitric-oxide synthase (type II) biosynthesis" NARROW [] +synonym: "positive regulation of nitric-oxide synthase (type II) biosynthetic process" NARROW [] +synonym: "positive regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "positive regulation of NO synthase biosynthesis" EXACT [] +synonym: "positive regulation of NO synthase biosynthetic process" EXACT [] +synonym: "positive regulation of NOS biosynthesis" EXACT [] +synonym: "positive regulation of NOS biosynthetic process" EXACT [] +synonym: "positive regulation of NOS2 synthase biosynthesis" NARROW [] +synonym: "positive regulation of NOS2 synthase biosynthetic process" NARROW [] +synonym: "stimulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "stimulation of nitric-oxide synthase biosynthetic process" NARROW [] +synonym: "up regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "up regulation of nitric-oxide synthase biosynthetic process" EXACT [] +synonym: "up-regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "up-regulation of nitric-oxide synthase biosynthetic process" EXACT [] +synonym: "upregulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "upregulation of nitric-oxide synthase biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0051769 ! regulation of nitric-oxide synthase biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051767 ! nitric-oxide synthase biosynthetic process +relationship: positively_regulates GO:0051767 ! nitric-oxide synthase biosynthetic process + +[Term] +id: GO:0051771 +name: negative regulation of nitric-oxide synthase biosynthetic process +namespace: biological_process +alt_id: GO:0051774 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme." [GOC:ai] +synonym: "down regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "down regulation of nitric-oxide synthase biosynthetic process" EXACT [] +synonym: "down-regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "down-regulation of nitric-oxide synthase biosynthetic process" EXACT [] +synonym: "downregulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "downregulation of nitric-oxide synthase biosynthetic process" EXACT [] +synonym: "inhibition of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "inhibition of nitric-oxide synthase biosynthetic process" NARROW [] +synonym: "negative regulation of nitric-oxide synthase (type 2) biosynthesis" NARROW [] +synonym: "negative regulation of nitric-oxide synthase (type 2) biosynthetic process" NARROW [] +synonym: "negative regulation of nitric-oxide synthase (type II) biosynthesis" NARROW [] +synonym: "negative regulation of nitric-oxide synthase (type II) biosynthetic process" NARROW [] +synonym: "negative regulation of nitric-oxide synthase 2 biosynthetic process" NARROW [] +synonym: "negative regulation of NO synthase biosynthesis" EXACT [] +synonym: "negative regulation of NO synthase biosynthetic process" EXACT [] +synonym: "negative regulation of NOS biosynthesis" EXACT [] +synonym: "negative regulation of NOS biosynthetic process" EXACT [] +synonym: "negative regulation of NOS2 synthase biosynthesis" NARROW [] +synonym: "negative regulation of NOS2 synthase biosynthetic process" NARROW [] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0051769 ! regulation of nitric-oxide synthase biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051767 ! nitric-oxide synthase biosynthetic process +relationship: negatively_regulates GO:0051767 ! nitric-oxide synthase biosynthetic process + +[Term] +id: GO:0051775 +name: response to redox state +namespace: biological_process +alt_id: GO:0006980 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important." [GOC:mah, PMID:15131240, PMID:16987039] +synonym: "redox signal response" EXACT [] +is_a: GO:0050896 ! response to stimulus + +[Term] +id: GO:0051776 +name: detection of redox state +namespace: biological_process +def: "The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important." [GOC:mah, PMID:15131240, PMID:16987039] +synonym: "redox sensing" EXACT [] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0051775 ! response to redox state + +[Term] +id: GO:0051777 +name: ent-kaurenoate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-159] +comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'. +synonym: "ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity" EXACT [EC:1.14.13.79] +synonym: "ent-kaurenoic acid oxidase activity" EXACT [] +xref: MetaCyc:1.14.13.79-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0051778 +name: ent-7-alpha-hydroxykaurenoate oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-160] +comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'. +xref: MetaCyc:RXN1F-160 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0051779 +name: gibberellin 12-aldehyde oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-161] +comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778'. +synonym: "GA12-aldehyde oxidase activity" EXACT [] +xref: MetaCyc:RXN1F-161 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0051780 +name: behavioral response to nutrient +namespace: biological_process +def: "Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus." [GOC:ai] +synonym: "behavioural response to nutrient" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0007584 ! response to nutrient + +[Term] +id: GO:0051781 +name: positive regulation of cell division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] +synonym: "activation of cell division" NARROW [] +synonym: "stimulation of cell division" NARROW [] +synonym: "up regulation of cell division" EXACT [] +synonym: "up-regulation of cell division" EXACT [] +synonym: "upregulation of cell division" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051301 ! cell division +relationship: positively_regulates GO:0051301 ! cell division + +[Term] +id: GO:0051782 +name: negative regulation of cell division +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai] +synonym: "down regulation of cell division" EXACT [] +synonym: "down-regulation of cell division" EXACT [] +synonym: "downregulation of cell division" EXACT [] +synonym: "inhibition of cell division" NARROW [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051301 ! cell division +relationship: negatively_regulates GO:0051301 ! cell division + +[Term] +id: GO:0051783 +name: regulation of nuclear division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000280 ! nuclear division +relationship: regulates GO:0000280 ! nuclear division + +[Term] +id: GO:0051784 +name: negative regulation of nuclear division +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] +synonym: "down regulation of nuclear division" EXACT [] +synonym: "down-regulation of nuclear division" EXACT [] +synonym: "downregulation of nuclear division" EXACT [] +synonym: "inhibition of nuclear division" NARROW [] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0051783 ! regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000280 ! nuclear division +relationship: negatively_regulates GO:0000280 ! nuclear division + +[Term] +id: GO:0051785 +name: positive regulation of nuclear division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] +synonym: "activation of nuclear division" NARROW [] +synonym: "stimulation of nuclear division" NARROW [] +synonym: "up regulation of nuclear division" EXACT [] +synonym: "up-regulation of nuclear division" EXACT [] +synonym: "upregulation of nuclear division" EXACT [] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0051783 ! regulation of nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000280 ! nuclear division +relationship: positively_regulates GO:0000280 ! nuclear division + +[Term] +id: GO:0051786 +name: all-trans-retinol 13,14-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction." [EC:1.3.99.23, RHEA:19193] +synonym: "(13,14)-all-trans-retinol saturase activity" EXACT [] +synonym: "all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity" EXACT [] +synonym: "all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity" EXACT [] +synonym: "retinol saturase activity" EXACT [EC:1.3.99.23] +synonym: "RetSat activity" EXACT [EC:1.3.99.23] +xref: EC:1.3.99.23 +xref: KEGG_REACTION:R07163 +xref: MetaCyc:1.3.99.23-RXN +xref: Reactome:R-HSA-8956427 "RETSAT reduces atROL to at-13,14-dhROL" +xref: RHEA:19193 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0051787 +name: misfolded protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a misfolded protein." [GOC:ai] +xref: Reactome:R-HSA-5324632 "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates" +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051788 +name: response to misfolded protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus." [GOC:go_curators] +is_a: GO:0035966 ! response to topologically incorrect protein + +[Term] +id: GO:0051789 +name: obsolete response to protein +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus." [GOC:ai] +comment: This term was made obsolete because more specific terms exist. +synonym: "response to protein" EXACT [] +synonym: "response to protein stimulus" EXACT [GOC:dos] +is_obsolete: true +consider: GO:0006986 +consider: GO:0009725 +consider: GO:0034097 +consider: GO:0051788 +consider: GO:0070848 + +[Term] +id: GO:0051790 +name: short-chain fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6." [Wikipedia:Fatty_acid_metabolism] +synonym: "short chain fatty acid biosynthesis" EXACT [] +synonym: "short chain fatty acid biosynthetic process" EXACT [] +synonym: "short-chain fatty acid anabolism" EXACT [] +synonym: "short-chain fatty acid biosynthesis" EXACT [] +synonym: "short-chain fatty acid formation" EXACT [] +synonym: "short-chain fatty acid synthesis" EXACT [] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0046459 ! short-chain fatty acid metabolic process + +[Term] +id: GO:0051791 +name: medium-chain fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12." [Wikipedia:Fatty_acid_metabolisms] +synonym: "medium chain fatty acid metabolic process" EXACT [] +synonym: "medium chain fatty acid metabolism" EXACT [] +synonym: "medium-chain fatty acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process + +[Term] +id: GO:0051792 +name: medium-chain fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12." [Wikipedia:Fatty_acid_metabolism] +synonym: "medium chain fatty acid biosynthesis" EXACT [] +synonym: "medium chain fatty acid biosynthetic process" EXACT [] +synonym: "medium-chain fatty acid anabolism" EXACT [] +synonym: "medium-chain fatty acid biosynthesis" EXACT [] +synonym: "medium-chain fatty acid formation" EXACT [] +synonym: "medium-chain fatty acid synthesis" EXACT [] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0051791 ! medium-chain fatty acid metabolic process + +[Term] +id: GO:0051793 +name: medium-chain fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12." [Wikipedia:Fatty_acid_metabolism] +synonym: "medium chain fatty acid catabolic process" EXACT [] +synonym: "medium chain fatty acid catabolism" EXACT [] +synonym: "medium-chain fatty acid breakdown" EXACT [] +synonym: "medium-chain fatty acid catabolism" EXACT [] +synonym: "medium-chain fatty acid degradation" EXACT [] +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:0051791 ! medium-chain fatty acid metabolic process + +[Term] +id: GO:0051794 +name: regulation of timing of catagen +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "regulation of catagen" RELATED [] +is_a: GO:0048819 ! regulation of hair follicle maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042637 ! catagen +relationship: regulates GO:0042637 ! catagen + +[Term] +id: GO:0051795 +name: positive regulation of timing of catagen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "activation of catagen" NARROW [] +synonym: "positive regulation of catagen" RELATED [] +synonym: "stimulation of catagen" NARROW [] +synonym: "up regulation of catagen" RELATED [] +synonym: "up-regulation of catagen" RELATED [] +synonym: "upregulation of catagen" RELATED [] +is_a: GO:0048818 ! positive regulation of hair follicle maturation +is_a: GO:0051794 ! regulation of timing of catagen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042637 ! catagen +relationship: positively_regulates GO:0042637 ! catagen + +[Term] +id: GO:0051796 +name: negative regulation of timing of catagen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "down regulation of catagen" RELATED [] +synonym: "down-regulation of catagen" RELATED [] +synonym: "downregulation of catagen" RELATED [] +synonym: "inhibition of catagen" NARROW [] +synonym: "negative regulation of catagen" RELATED [] +is_a: GO:0048817 ! negative regulation of hair follicle maturation +is_a: GO:0051794 ! regulation of timing of catagen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042637 ! catagen +relationship: negatively_regulates GO:0042637 ! catagen + +[Term] +id: GO:0051797 +name: regulation of hair follicle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hair follicle development." [GOC:ai] +is_a: GO:0042634 ! regulation of hair cycle +is_a: GO:0045682 ! regulation of epidermis development +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001942 ! hair follicle development +relationship: regulates GO:0001942 ! hair follicle development + +[Term] +id: GO:0051798 +name: positive regulation of hair follicle development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hair follicle development." [GOC:ai] +synonym: "activation of hair follicle development" NARROW [] +synonym: "stimulation of hair follicle development" NARROW [] +synonym: "up regulation of hair follicle development" EXACT [] +synonym: "up-regulation of hair follicle development" EXACT [] +synonym: "upregulation of hair follicle development" EXACT [] +is_a: GO:0042635 ! positive regulation of hair cycle +is_a: GO:0045684 ! positive regulation of epidermis development +is_a: GO:0051797 ! regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001942 ! hair follicle development +relationship: positively_regulates GO:0001942 ! hair follicle development + +[Term] +id: GO:0051799 +name: negative regulation of hair follicle development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development." [GOC:ai] +synonym: "down regulation of hair follicle development" EXACT [] +synonym: "down-regulation of hair follicle development" EXACT [] +synonym: "downregulation of hair follicle development" EXACT [] +synonym: "inhibition of hair follicle development" NARROW [] +is_a: GO:0042636 ! negative regulation of hair cycle +is_a: GO:0045683 ! negative regulation of epidermis development +is_a: GO:0051797 ! regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001942 ! hair follicle development +relationship: negatively_regulates GO:0001942 ! hair follicle development + +[Term] +id: GO:0051800 +name: phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate." [GOC:bf, PMID:9811831] +synonym: "PTEN activity" BROAD [] +xref: Reactome:R-HSA-1676149 "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane" +xref: Reactome:R-HSA-1676204 "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane" +is_a: GO:0106017 ! phosphatidylinositol-3,4-bisphosphate phosphatase activity + +[Term] +id: GO:0051801 +name: cytolysis in other organism involved in symbiotic interaction +namespace: biological_process +def: "The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction." [GOC:add] +synonym: "cytolysis of cells in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "cytolysis of cells in other organism involved in symbiotic interaction" EXACT [GOC:bf] +is_a: GO:0051715 ! cytolysis in other organism +is_a: GO:0051883 ! killing of cells in other organism involved in symbiotic interaction + +[Term] +id: GO:0051802 +name: regulation of cytolysis in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction." [GOC:add] +synonym: "regulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "regulation of cytolysis of cells in other organism involved in symbiotic interaction" EXACT [GOC:bf] +is_a: GO:0051710 ! regulation of cytolysis in other organism +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +relationship: regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction + +[Term] +id: GO:0051803 +name: negative regulation of cytolysis in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction." [GOC:add] +synonym: "down regulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [] +synonym: "down-regulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [] +synonym: "downregulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [] +synonym: "inhibition of cytolysis of cells in other organism during symbiotic interaction" NARROW [] +synonym: "negative regulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "negative regulation of cytolysis of cells in other organism involved in symbiotic interaction" EXACT [GOC:bf] +is_a: GO:0051713 ! negative regulation of cytolysis in other organism +is_a: GO:0051802 ! regulation of cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +relationship: negatively_regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction + +[Term] +id: GO:0051804 +name: positive regulation of cytolysis in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction." [GOC:add] +synonym: "activation of cytolysis of cells in other organism during symbiotic interaction" NARROW [] +synonym: "positive regulation of cytolysis of cells in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "positive regulation of cytolysis of cells in other organism involved in symbiotic interaction" EXACT [GOC:bf] +synonym: "stimulation of cytolysis of cells in other organism during symbiotic interaction" NARROW [] +synonym: "up regulation of cytolysis of cells in other organism during symbiotic interaction" EXACT [] +synonym: "up-regulation of cytolysis of cells in other organism during symbiotic interaction" EXACT [] +synonym: "upregulation of cytolysis of cells in other organism during symbiotic interaction" EXACT [] +is_a: GO:0051714 ! positive regulation of cytolysis in other organism +is_a: GO:0051802 ! regulation of cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +relationship: positively_regulates GO:0051801 ! cytolysis in other organism involved in symbiotic interaction + +[Term] +id: GO:0051814 +name: obsolete movement in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction." [GOC:cc] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "movement in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "movement within other organism during symbiotic interaction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051815 +name: obsolete migration in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction." [GOC:cc] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "migration in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "migration within other organism during symbiotic interaction" RELATED [] +is_obsolete: true + +[Term] +id: GO:0051816 +name: acquisition of nutrients from other organism during symbiotic interaction +namespace: biological_process +def: "The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction." [GOC:cc] +is_a: GO:0044403 ! symbiotic process + +[Term] +id: GO:0051817 +name: modulation of process of other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction." [GOC:cc] +synonym: "modification of morphology or physiology of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "modification of morphology or physiology of other organism involved in symbiotic interaction" RELATED [] +synonym: "modulation of biological process of other organism involved in symbiotic interaction" RELATED [] +synonym: "modulation of morphology or physiology of other organism during symbiotic interaction" RELATED [] +synonym: "regulation of morphology of other organism during symbiotic interaction" NARROW [] +synonym: "regulation of morphology or physiology of other organism during symbiotic interaction" RELATED [] +synonym: "regulation of physiological process in other organism during symbiotic interaction" NARROW [] +synonym: "regulation of physiology of other organism during symbiotic interaction" NARROW [] +is_a: GO:0035821 ! modulation of process of other organism +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI + +[Term] +id: GO:0051818 +name: disruption of cells of other organism involved in symbiotic interaction +namespace: biological_process +def: "A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction." [GOC:cc] +synonym: "disruption of cells of other organism during symbiotic interaction" RELATED [GOC:tb] +is_a: GO:0044364 ! disruption of cells of other organism +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0051819 +name: induction by symbiont of tumor or growth in host +namespace: biological_process +alt_id: GO:0044005 +alt_id: GO:0044006 +alt_id: GO:0051820 +def: "The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic." [GOC:pg] +synonym: "induction by symbiont in host of tumor, nodule, or growth" RELATED [] +synonym: "induction by symbiont in host of tumor, nodule, or growth containing transformed cells" RELATED [] +synonym: "induction by symbiont of nodulation, tumor or growth in host" RELATED [] +synonym: "induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction" RELATED [] +synonym: "induction of tumor, nodule, or growth in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "induction of tumor, nodule, or growth in other organism involved in symbiotic interaction" RELATED [] +is_a: GO:0044003 ! modulation by symbiont of host process + +[Term] +id: GO:0051821 +name: obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism." [GOC:cc] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont. +synonym: "dissemination or transmission of organism from other organism during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0051822 +name: obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal." [GOC:cc] +comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont. +synonym: "dissemination or transmission of organism from other organism by vector during symbiotic interaction" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0051823 +name: regulation of synapse structural plasticity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane." [PMID:11063967, PMID:14976517, PMID:9884123] +synonym: "regulation of synaptic structural plasticity" EXACT [] +is_a: GO:0050807 ! regulation of synapse organization + +[Term] +id: GO:0051826 +name: negative regulation of synapse structural plasticity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity." [GOC:ai] +synonym: "down regulation of synapse structural plasticity" EXACT [] +synonym: "down-regulation of synapse structural plasticity" EXACT [] +synonym: "downregulation of synapse structural plasticity" EXACT [] +synonym: "inhibition of synapse structural plasticity" NARROW [] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051823 ! regulation of synapse structural plasticity + +[Term] +id: GO:0051827 +name: obsolete growth or development on or near surface of other organism during symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'growth on or near surface of other organism during symbiotic interaction ; GO:0044153' and 'development on or near surface of other organism during symbiotic interaction ; GO:0044152'. +synonym: "growth or development on or near surface of other organism during symbiotic interaction" EXACT [] +is_obsolete: true +consider: GO:0044110 +consider: GO:0044111 + +[Term] +id: GO:0051831 +name: obsolete growth or development in other organism during symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism." [GOC:cc] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'growth in other organism during symbiotic interaction ; GO:0044112' and 'development in other organism during symbiotic interaction ; GO:0044113'. +synonym: "growth or development in other organism during symbiotic interaction" EXACT [] +synonym: "growth or development within other organism during symbiotic interaction" EXACT [] +synonym: "invasive growth" BROAD [] +is_obsolete: true +consider: GO:0044113 +consider: GO:0044117 + +[Term] +id: GO:0051835 +name: positive regulation of synapse structural plasticity +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity." [GOC:ai] +synonym: "activation of synapse structural plasticity" NARROW [] +synonym: "stimulation of synapse structural plasticity" NARROW [] +synonym: "up regulation of synapse structural plasticity" EXACT [] +synonym: "up-regulation of synapse structural plasticity" EXACT [] +synonym: "upregulation of synapse structural plasticity" EXACT [] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051823 ! regulation of synapse structural plasticity + +[Term] +id: GO:0051838 +name: cytolysis by host of symbiont cells +namespace: biological_process +def: "The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add] +is_a: GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +is_a: GO:0051873 ! killing by host of symbiont cells +relationship: has_part GO:0052337 ! modification by host of symbiont membrane + +[Term] +id: GO:0051839 +name: regulation by host of cytolysis of symbiont cells +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0051802 ! regulation of cytolysis in other organism involved in symbiotic interaction +relationship: regulates GO:0051838 ! cytolysis by host of symbiont cells + +[Term] +id: GO:0051840 +name: negative regulation by host of cytolysis of symbiont cells +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add] +synonym: "down regulation by host of cytolysis of symbiont cells" EXACT [] +synonym: "down-regulation by host of cytolysis of symbiont cells" EXACT [] +synonym: "downregulation by host of cytolysis of symbiont cells" EXACT [] +synonym: "inhibition by host of cytolysis of symbiont cells" NARROW [] +is_a: GO:0051803 ! negative regulation of cytolysis in other organism involved in symbiotic interaction +is_a: GO:0051839 ! regulation by host of cytolysis of symbiont cells + +[Term] +id: GO:0051841 +name: positive regulation by host of cytolysis of symbiont cells +namespace: biological_process +def: "Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add] +synonym: "activation by host of cytolysis of symbiont cells" NARROW [] +synonym: "stimulation by host of cytolysis of symbiont cells" NARROW [] +synonym: "up regulation by host of cytolysis of symbiont cells" EXACT [] +synonym: "up-regulation by host of cytolysis of symbiont cells" EXACT [] +synonym: "upregulation by host of cytolysis of symbiont cells" EXACT [] +is_a: GO:0051804 ! positive regulation of cytolysis in other organism involved in symbiotic interaction +is_a: GO:0051839 ! regulation by host of cytolysis of symbiont cells + +[Term] +id: GO:0051842 +name: obsolete evasion or tolerance of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mb] +comment: This term was made obsolete because it does not represent a valid biological process that occurs in nature. +synonym: "evasion or tolerance of symbiont immune response" EXACT [] +synonym: "immune evasion" BROAD [] +is_obsolete: true + +[Term] +id: GO:0051843 +name: obsolete evasion or tolerance of symbiont defense response +namespace: biological_process +def: "OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mah] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "evasion of symbiont defence response" EXACT [] +synonym: "evasion or tolerance of symbiont defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051844 +name: translocation of peptides or proteins into symbiont +namespace: biological_process +def: "The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "transport of peptides or proteins into symbiont" EXACT [] +is_a: GO:0051862 ! translocation of molecules into symbiont + +[Term] +id: GO:0051845 +name: obsolete passive evasion of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [PMID:12439615] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "passive evasion of symbiont immune response" EXACT [] +synonym: "passive immune evasion" BROAD [] +is_obsolete: true + +[Term] +id: GO:0051846 +name: obsolete active evasion of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [PMID:12439615] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "active evasion of symbiont immune response" EXACT [] +synonym: "active immune evasion" BROAD [] +is_obsolete: true + +[Term] +id: GO:0051847 +name: obsolete active evasion of symbiont immune response via regulation of symbiont complement system +namespace: biological_process +def: "OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [http://www.brown.edu/Courses/Bio_160/Projects1999/ies/ces.html] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "active evasion of symbiont immune response via regulation of symbiont complement system" EXACT [] +synonym: "active immune evasion via modulation of symbiont complement system" EXACT [] +synonym: "active immune evasion via regulation of symbiont complement system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051848 +name: obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network +namespace: biological_process +def: "OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [http://www.brown.edu/Courses/Bio_160/Projects1999/ies/cytok.html#Manipulation] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "active evasion of symbiont immune response via regulation of symbiont cytokine network" EXACT [] +synonym: "active immune evasion via modulation of symbiont cytokine network" EXACT [] +synonym: "active immune evasion via regulation of symbiont cytokine network" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051849 +name: obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation +namespace: biological_process +def: "OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [PMID:12439615] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation" EXACT [] +synonym: "active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway" EXACT [] +synonym: "active immune evasion via modulation of symbiont antigen processing and presentation" EXACT [] +synonym: "active immune evasion via modulation of symbiont antigen processing/presentation" EXACT [] +synonym: "active immune evasion via regulation of symbiont antigen processing or presentation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051850 +name: acquisition of nutrients from symbiont +namespace: biological_process +def: "The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +is_a: GO:0051702 ! interaction with symbiont +is_a: GO:0051816 ! acquisition of nutrients from other organism during symbiotic interaction + +[Term] +id: GO:0051851 +name: modulation by host of symbiont process +namespace: biological_process +def: "The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "modification by host of symbiont morphology or physiology" RELATED [] +is_a: GO:0051702 ! interaction with symbiont +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0051853 +name: obsolete induction in symbiont of tumor, nodule, or growth +namespace: biological_process +def: "OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "induction in symbiont of tumor, nodule, or growth" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051854 +name: obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells +namespace: biological_process +def: "OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "induction in symbiont of tumor, nodule, or growth containing transformed cells" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051857 +name: obsolete growth or development of organism on or near symbiont surface +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "growth or development of organism during interaction with symbiont" EXACT [] +synonym: "growth or development of organism on or near symbiont surface" EXACT [] +is_obsolete: true +consider: GO:0032502 + +[Term] +id: GO:0051858 +name: obsolete avoidance of symbiont defenses +namespace: biological_process +def: "OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it is not relevant for the host in a host-symbiont interaction. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14862 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051859 +name: obsolete suppression of symbiont defenses +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it is not relevant for the host in a host-symbiont interaction. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14862 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051860 +name: obsolete evasion or tolerance of symbiont defenses +namespace: biological_process +def: "OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it is not relevant for the host in a host-symbiont interaction. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14862 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0051861 +name: glycolipid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate." [PMID:19635802] +is_a: GO:0008289 ! lipid binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0051862 +name: translocation of molecules into symbiont +namespace: biological_process +def: "The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +synonym: "transport of molecules into symbiont" EXACT [] +is_a: GO:0051702 ! interaction with symbiont + +[Term] +id: GO:0051863 +name: obsolete translocation of DNA into symbiont +namespace: biological_process +def: "OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: This term was made obsolete because it does not represent a real process that exists in nature. +synonym: "translocation of DNA into symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0051864 +name: histone demethylase activity (H3-K36 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein." [PMID:16362057] +synonym: "[histone-H3]-lysine-36 demethylase activity" EXACT [] +synonym: "H3-K36-specific demethylase activity" EXACT [EC:1.14.11.27] +synonym: "histone H3-lysine-36 demethylase activity" EXACT [EC:1.14.11.27] +synonym: "histone-lysine (H3-K36) demethylase activity" EXACT [EC:1.14.11.27] +synonym: "histone-lysine demethylase activity (H3-K36 specific)" EXACT [] +synonym: "histone-lysine(H3-K36) demethylase activity" EXACT [] +synonym: "JHDM1A activity" NARROW [EC:1.14.11.27] +synonym: "JmjC domain-containing histone demethylase 1A activity" NARROW [EC:1.14.11.27] +synonym: "protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] +synonym: "protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] +xref: EC:1.14.11.27 +xref: MetaCyc:RXN-8660 +xref: MetaCyc:RXN-8661 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0070544 ! histone H3-K36 demethylation + +[Term] +id: GO:0051865 +name: protein autoubiquitination +namespace: biological_process +def: "The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink." [GOC:ai] +synonym: "protein auto-ubiquitination" EXACT [] +synonym: "protein auto-ubiquitinylation" EXACT [] +synonym: "protein autoubiquitinylation" EXACT [] +synonym: "protein self-ubiquitination" EXACT [] +synonym: "protein self-ubiquitinylation" EXACT [] +is_a: GO:0016567 ! protein ubiquitination + +[Term] +id: GO:0051866 +name: general adaptation syndrome +namespace: biological_process +alt_id: GO:0051868 +def: "General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses." [PMID:14847556, Wikipedia:General_adaptation_syndrome] +synonym: "general adaptation syndrome, physiological process" EXACT [] +synonym: "general adaptation syndrome, physiological response" EXACT [] +synonym: "physiological process during general adaptation syndrome" EXACT [] +synonym: "physiological response during general adaptation syndrome" EXACT [] +is_a: GO:0033555 ! multicellular organismal response to stress + +[Term] +id: GO:0051867 +name: general adaptation syndrome, behavioral process +namespace: biological_process +def: "The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus." [GOC:ai] +synonym: "behavioral process during general adaptation syndrome" EXACT [] +synonym: "behavioral response during general adaptation syndrome" EXACT [] +synonym: "behavioural process during general adaptation syndrome" EXACT [] +synonym: "behavioural response during general adaptation syndrome" EXACT [] +synonym: "general adaptation syndrome, behavioral response" EXACT [] +synonym: "general adaptation syndrome, behavioural process" EXACT [] +synonym: "general adaptation syndrome, behavioural response" EXACT [] +is_a: GO:0007610 ! behavior +relationship: part_of GO:0051866 ! general adaptation syndrome + +[Term] +id: GO:0051870 +name: methotrexate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA." [GOC:nln] +is_a: GO:0008144 ! drug binding +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0033218 ! amide binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0051871 +name: dihydrofolic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms." [ISBN:0721662544] +synonym: "DHF binding" RELATED [] +synonym: "dihydrofolate binding" RELATED [] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0033218 ! amide binding +is_a: GO:0072341 ! modified amino acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0051872 +name: sphingosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues." [GOC:ai] +synonym: "(4E)-sphing-4-enine catabolic process" EXACT [] +synonym: "(4E)-sphing-4-enine catabolism" EXACT [] +synonym: "sphing-4-enine catabolic process" EXACT [] +synonym: "sphing-4-enine catabolism" EXACT [] +is_a: GO:0006670 ! sphingosine metabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0046521 ! sphingoid catabolic process + +[Term] +id: GO:0051873 +name: killing by host of symbiont cells +namespace: biological_process +alt_id: GO:0051852 +def: "Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add] +synonym: "disruption by host of symbiont cells" BROAD [] +is_a: GO:0051702 ! interaction with symbiont +is_a: GO:0051883 ! killing of cells in other organism involved in symbiotic interaction +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18719 xsd:anyURI + +[Term] +id: GO:0051874 +name: sphinganine-1-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol." [GOC:ai] +synonym: "dihydrosphingosine-1-phosphate catabolic process" EXACT [] +synonym: "dihydrosphingosine-1-phosphate catabolism" EXACT [] +is_a: GO:0006668 ! sphinganine-1-phosphate metabolic process +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0030149 ! sphingolipid catabolic process + +[Term] +id: GO:0051875 +name: pigment granule localization +namespace: biological_process +def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] +synonym: "pigment granule localisation" EXACT [GOC:mah] +is_a: GO:0051648 ! vesicle localization +relationship: part_of GO:0033059 ! cellular pigmentation + +[Term] +id: GO:0051876 +name: pigment granule dispersal +namespace: biological_process +def: "The directed movement of pigment granules within a cell towards the cell periphery." [GOC:mh] +is_a: GO:0051905 ! establishment of pigment granule localization + +[Term] +id: GO:0051877 +name: pigment granule aggregation in cell center +namespace: biological_process +def: "The directed movement of dispersed pigment granules towards the center of the cell." [GOC:mh] +is_a: GO:0051905 ! establishment of pigment granule localization + +[Term] +id: GO:0051878 +name: lateral element assembly +namespace: biological_process +def: "The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements." [PMID:11463847] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007130 ! synaptonemal complex assembly + +[Term] +id: GO:0051879 +name: Hsp90 protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size." [GOC:ai] +synonym: "Hsp90 binding" EXACT [] +synonym: "Hsp90 class protein binding" EXACT [] +is_a: GO:0031072 ! heat shock protein binding + +[Term] +id: GO:0051880 +name: G-quadruplex DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome." [PMID:16142245, PMID:9512530] +synonym: "G quadruplex DNA binding" EXACT [GOC:mah] +synonym: "G quartet binding" BROAD [GOC:mah] +synonym: "G quartet DNA binding" EXACT [GOC:mah] +synonym: "G-DNA binding" EXACT [] +synonym: "G-quartet binding" BROAD [GOC:mah] +synonym: "G-quartet DNA binding" EXACT [GOC:mah] +synonym: "quadruplex DNA binding" EXACT [] +synonym: "tetraplex DNA binding" EXACT [] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0051881 +name: regulation of mitochondrial membrane potential +namespace: biological_process +def: "Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:ai] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0051882 +name: mitochondrial depolarization +namespace: biological_process +def: "The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level." [Wikipedia:Depolarization, Wikipedia:Mitochondrion] +synonym: "mitochondria depolarization" EXACT [] +synonym: "mitochondrial depolarisation" EXACT [] +synonym: "mitochondrial membrane depolarization" EXACT [] +synonym: "mitochondrion depolarization" EXACT [] +is_a: GO:0051881 ! regulation of mitochondrial membrane potential +is_a: GO:0051899 ! membrane depolarization +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0051883 +name: killing of cells in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction." [GOC:add] +synonym: "killing of cells in other organism during symbiotic interaction" RELATED [GOC:tb] +is_a: GO:0031640 ! killing of cells of other organism +is_a: GO:0044419 ! interspecies interaction between organisms + +[Term] +id: GO:0051884 +name: regulation of timing of anagen +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "regulation of anagen" RELATED [] +is_a: GO:0048819 ! regulation of hair follicle maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042640 ! anagen +relationship: regulates GO:0042640 ! anagen + +[Term] +id: GO:0051885 +name: positive regulation of timing of anagen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "activation of anagen" NARROW [] +synonym: "positive regulation of anagen" RELATED [] +synonym: "stimulation of anagen" NARROW [] +synonym: "up regulation of anagen" RELATED [] +synonym: "up-regulation of anagen" RELATED [] +synonym: "upregulation of anagen" RELATED [] +is_a: GO:0048818 ! positive regulation of hair follicle maturation +is_a: GO:0051884 ! regulation of timing of anagen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042640 ! anagen +relationship: positively_regulates GO:0042640 ! anagen + +[Term] +id: GO:0051886 +name: negative regulation of timing of anagen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "down regulation of anagen" RELATED [] +synonym: "down-regulation of anagen" RELATED [] +synonym: "downregulation of anagen" RELATED [] +synonym: "inhibition of anagen" NARROW [] +synonym: "negative regulation of anagen" RELATED [] +is_a: GO:0048817 ! negative regulation of hair follicle maturation +is_a: GO:0051884 ! regulation of timing of anagen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042640 ! anagen +relationship: negatively_regulates GO:0042640 ! anagen + +[Term] +id: GO:0051887 +name: regulation of timing of exogen +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "regulation of exogen" RELATED [] +is_a: GO:0048819 ! regulation of hair follicle maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042638 ! exogen +relationship: regulates GO:0042638 ! exogen + +[Term] +id: GO:0051888 +name: positive regulation of timing of exogen +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "activation of exogen" NARROW [] +synonym: "positive regulation of exogen" RELATED [] +synonym: "stimulation of exogen" NARROW [] +synonym: "up regulation of exogen" RELATED [] +synonym: "up-regulation of exogen" RELATED [] +synonym: "upregulation of exogen" RELATED [] +is_a: GO:0048818 ! positive regulation of hair follicle maturation +is_a: GO:0051887 ! regulation of timing of exogen +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042638 ! exogen +relationship: positively_regulates GO:0042638 ! exogen + +[Term] +id: GO:0051889 +name: negative regulation of timing of exogen +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle." [GOC:ai, GOC:pr] +synonym: "down regulation of exogen" RELATED [] +synonym: "down-regulation of exogen" RELATED [] +synonym: "downregulation of exogen" RELATED [] +synonym: "inhibition of exogen" NARROW [] +synonym: "negative regulation of exogen" RELATED [] +is_a: GO:0048817 ! negative regulation of hair follicle maturation +is_a: GO:0051887 ! regulation of timing of exogen +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042638 ! exogen +relationship: negatively_regulates GO:0042638 ! exogen + +[Term] +id: GO:0051890 +name: regulation of cardioblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] +is_a: GO:1905207 ! regulation of cardiocyte differentiation +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010002 ! cardioblast differentiation +relationship: regulates GO:0010002 ! cardioblast differentiation + +[Term] +id: GO:0051891 +name: positive regulation of cardioblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] +synonym: "activation of cardioblast differentiation" NARROW [] +synonym: "stimulation of cardioblast differentiation" NARROW [] +synonym: "up regulation of cardioblast differentiation" EXACT [] +synonym: "up-regulation of cardioblast differentiation" EXACT [] +synonym: "upregulation of cardioblast differentiation" EXACT [] +is_a: GO:0051890 ! regulation of cardioblast differentiation +is_a: GO:1905209 ! positive regulation of cardiocyte differentiation +is_a: GO:2000738 ! positive regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010002 ! cardioblast differentiation +relationship: positively_regulates GO:0010002 ! cardioblast differentiation + +[Term] +id: GO:0051892 +name: negative regulation of cardioblast differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] +synonym: "down regulation of cardioblast differentiation" EXACT [] +synonym: "down-regulation of cardioblast differentiation" EXACT [] +synonym: "downregulation of cardioblast differentiation" EXACT [] +synonym: "inhibition of cardioblast differentiation" NARROW [] +is_a: GO:0051890 ! regulation of cardioblast differentiation +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +is_a: GO:2000737 ! negative regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010002 ! cardioblast differentiation +relationship: negatively_regulates GO:0010002 ! cardioblast differentiation + +[Term] +id: GO:0051893 +name: regulation of focal adhesion assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions." [GOC:ai] +synonym: "regulation of adhesion plaque assembly" RELATED [] +is_a: GO:0001952 ! regulation of cell-matrix adhesion +is_a: GO:0090109 ! regulation of cell-substrate junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0048041 ! focal adhesion assembly +relationship: regulates GO:0048041 ! focal adhesion assembly + +[Term] +id: GO:0051894 +name: positive regulation of focal adhesion assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions." [GOC:ai] +synonym: "activation of focal adhesion formation" NARROW [] +synonym: "stimulation of focal adhesion formation" NARROW [] +synonym: "up regulation of focal adhesion formation" EXACT [] +synonym: "up-regulation of focal adhesion formation" EXACT [] +synonym: "upregulation of focal adhesion formation" EXACT [] +is_a: GO:0001954 ! positive regulation of cell-matrix adhesion +is_a: GO:0051893 ! regulation of focal adhesion assembly +is_a: GO:0150117 ! positive regulation of cell-substrate junction organization +is_a: GO:1901890 ! positive regulation of cell junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0048041 ! focal adhesion assembly +relationship: positively_regulates GO:0048041 ! focal adhesion assembly + +[Term] +id: GO:0051895 +name: negative regulation of focal adhesion assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions." [GOC:ai] +synonym: "down regulation of focal adhesion formation" EXACT [] +synonym: "down-regulation of focal adhesion formation" EXACT [] +synonym: "downregulation of focal adhesion formation" EXACT [] +synonym: "inhibition of focal adhesion formation" NARROW [] +is_a: GO:0001953 ! negative regulation of cell-matrix adhesion +is_a: GO:0051893 ! regulation of focal adhesion assembly +is_a: GO:0150118 ! negative regulation of cell-substrate junction organization +is_a: GO:1901889 ! negative regulation of cell junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0048041 ! focal adhesion assembly +relationship: negatively_regulates GO:0048041 ! focal adhesion assembly + +[Term] +id: GO:0051896 +name: regulation of protein kinase B signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] +synonym: "regulation of AKT signaling cascade" RELATED [] +synonym: "regulation of AKT signalling cascade" RELATED [] +synonym: "regulation of PKB signaling cascade" RELATED [] +synonym: "regulation of PKB signalling cascade" RELATED [] +synonym: "regulation of protein kinase B signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of protein kinase B signalling cascade" RELATED [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043491 ! protein kinase B signaling +relationship: regulates GO:0043491 ! protein kinase B signaling + +[Term] +id: GO:0051897 +name: positive regulation of protein kinase B signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] +synonym: "activation of protein kinase B signaling cascade" NARROW [] +synonym: "positive regulation of AKT signaling cascade" RELATED [] +synonym: "positive regulation of AKT signalling cascade" EXACT [] +synonym: "positive regulation of PKB signaling cascade" EXACT [] +synonym: "positive regulation of PKB signalling cascade" RELATED [] +synonym: "positive regulation of protein kinase B signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of protein kinase B signalling cascade" RELATED [] +synonym: "stimulation of protein kinase B signaling cascade" NARROW [] +synonym: "up regulation of protein kinase B signaling cascade" RELATED [] +synonym: "up-regulation of protein kinase B signaling cascade" RELATED [] +synonym: "upregulation of protein kinase B signaling cascade" RELATED [] +is_a: GO:0051896 ! regulation of protein kinase B signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043491 ! protein kinase B signaling +relationship: positively_regulates GO:0043491 ! protein kinase B signaling + +[Term] +id: GO:0051898 +name: negative regulation of protein kinase B signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] +synonym: "down regulation of protein kinase B signaling cascade" RELATED [] +synonym: "down-regulation of protein kinase B signaling cascade" RELATED [] +synonym: "downregulation of protein kinase B signaling cascade" RELATED [] +synonym: "inhibition of protein kinase B signaling cascade" NARROW [] +synonym: "negative regulation of AKT signaling cascade" RELATED [] +synonym: "negative regulation of AKT signalling cascade" EXACT [] +synonym: "negative regulation of PKB signaling cascade" EXACT [] +synonym: "negative regulation of PKB signalling cascade" RELATED [] +synonym: "negative regulation of protein kinase B signaling cascade" RELATED [GOC:signaling] +synonym: "negative regulation of protein kinase B signalling cascade" RELATED [] +is_a: GO:0051896 ! regulation of protein kinase B signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043491 ! protein kinase B signaling +relationship: negatively_regulates GO:0043491 ! protein kinase B signaling + +[Term] +id: GO:0051899 +name: membrane depolarization +namespace: biological_process +def: "The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:dh, Wikipedia:Depolarization] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0051900 +name: regulation of mitochondrial depolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] +is_a: GO:0003254 ! regulation of membrane depolarization +is_a: GO:0051881 ! regulation of mitochondrial membrane potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051882 ! mitochondrial depolarization +relationship: regulates GO:0051882 ! mitochondrial depolarization + +[Term] +id: GO:0051901 +name: positive regulation of mitochondrial depolarization +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] +synonym: "activation of mitochondrial depolarization" NARROW [] +synonym: "stimulation of mitochondrial depolarization" NARROW [] +synonym: "up regulation of mitochondrial depolarization" EXACT [] +synonym: "up-regulation of mitochondrial depolarization" EXACT [] +synonym: "upregulation of mitochondrial depolarization" EXACT [] +is_a: GO:0051900 ! regulation of mitochondrial depolarization +is_a: GO:1904181 ! positive regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051882 ! mitochondrial depolarization +relationship: positively_regulates GO:0051882 ! mitochondrial depolarization + +[Term] +id: GO:0051902 +name: negative regulation of mitochondrial depolarization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] +synonym: "down regulation of mitochondrial depolarization" EXACT [] +synonym: "down-regulation of mitochondrial depolarization" EXACT [] +synonym: "downregulation of mitochondrial depolarization" EXACT [] +synonym: "inhibition of mitochondrial depolarization" NARROW [] +is_a: GO:0051900 ! regulation of mitochondrial depolarization +is_a: GO:1904180 ! negative regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051882 ! mitochondrial depolarization +relationship: negatively_regulates GO:0051882 ! mitochondrial depolarization + +[Term] +id: GO:0051903 +name: S-(hydroxymethyl)glutathione dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+." [EC:1.1.1.284] +synonym: "ADH3 activity" NARROW [EC:1.1.1.284] +synonym: "chi-ADH activity" NARROW [EC:1.1.1.284] +synonym: "class III alcohol dehydrogenase activity" RELATED [EC:1.1.1.284] +synonym: "FDH activity" RELATED [EC:1.1.1.284] +synonym: "formic dehydrogenase activity" RELATED [EC:1.1.1.284] +synonym: "GD-FALDH activity" EXACT [EC:1.1.1.284] +synonym: "glutathione-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] +synonym: "GS-FDH activity" EXACT [EC:1.1.1.284] +synonym: "NAD- and glutathione-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] +synonym: "NAD-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] +synonym: "NAD-linked formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] +synonym: "S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.284] +xref: EC:1.1.1.284 +xref: KEGG_REACTION:R06983 +xref: KEGG_REACTION:R07140 +xref: MetaCyc:RXN-2962 +xref: Reactome:R-HSA-5692237 "ADH5 oxidises S-HMGSH to S-FGSH" +xref: RHEA:19981 +xref: RHEA:19985 +xref: UM-BBD_reactionID:r1146 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0051904 +name: pigment granule transport +namespace: biological_process +def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "pigment granule translocation" EXACT [] +is_a: GO:0006810 ! transport +is_a: GO:0051875 ! pigment granule localization +is_a: GO:0051905 ! establishment of pigment granule localization + +[Term] +id: GO:0051905 +name: establishment of pigment granule localization +namespace: biological_process +def: "The directed movement of a pigment granule to a specific location." [GOC:ai] +synonym: "establishment of pigment granule localisation" EXACT [GOC:mah] +is_a: GO:0051650 ! establishment of vesicle localization +relationship: part_of GO:0051875 ! pigment granule localization + +[Term] +id: GO:0051906 +name: maintenance of pigment granule location +namespace: biological_process +def: "Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere." [GOC:ai, GOC:dph, GOC:tb] +synonym: "maintenance of pigment granule localization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051655 ! maintenance of vesicle location +relationship: part_of GO:0051875 ! pigment granule localization + +[Term] +id: GO:0051907 +name: S-(hydroxymethyl)glutathione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione." [EC:4.4.1.22, RHEA:22488] +synonym: "Gfa" RELATED [EC:4.4.1.22] +synonym: "glutathione-dependent formaldehyde-activating enzyme activity" EXACT [] +synonym: "S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)" EXACT [EC:4.4.1.22] +synonym: "S-(hydroxymethyl)glutathione formaldehyde-lyase activity" EXACT [EC:4.4.1.22] +xref: EC:4.4.1.22 +xref: KEGG_REACTION:R06982 +xref: MetaCyc:RXN-2961 +xref: RHEA:22488 +xref: UM-BBD_reactionID:r1145 +is_a: GO:0016846 ! carbon-sulfur lyase activity + +[Term] +id: GO:0051908 +name: double-stranded DNA 5'-3' exodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule." [GOC:ai] +synonym: "double-stranded DNA specific 5'-3' exodeoxyribonuclease activity" RELATED [] +is_a: GO:0008309 ! double-stranded DNA exodeoxyribonuclease activity +is_a: GO:0035312 ! 5'-3' exodeoxyribonuclease activity + +[Term] +id: GO:0051909 +name: acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate +namespace: molecular_function +def: "Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O." [MetaCyc:ACETYLENECARBOXYLATE-HYDRATASE-RXN] +synonym: "3-hydroxypropenoate dehydratase activity" EXACT [] +synonym: "acetylenecarboxylate hydratase activity" BROAD [] +synonym: "acetylenemonocarboxylate hydratase activity" BROAD [] +synonym: "alkynoate hydratase activity" BROAD [] +xref: EC:4.2.1.27 +xref: RHEA:17957 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0051911 +name: Methanosarcina-phenazine hydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine." [EC:1.12.98.3] +synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity" RELATED [] +synonym: "hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity" EXACT [EC:1.12.98.3] +synonym: "methanophenazine hydrogenase activity" EXACT [] +synonym: "methylviologen-reducing hydrogenase activity" EXACT [] +xref: EC:1.12.98.3 +xref: MetaCyc:RXN-7733 +xref: RHEA:24436 +is_a: GO:0046995 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors + +[Term] +id: GO:0051912 +name: CoB--CoM heterodisulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine." [EC:1.8.98.1] +synonym: "CoB-CoM heterodisulfide reductase activity" EXACT [] +synonym: "coenzyme B--coenzyme M heterodisulfide reductase activity" EXACT [] +synonym: "coenzyme B:coenzyme M:methanophenazine oxidoreductase activity" EXACT [EC:1.8.98.1] +synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity" RELATED [] +synonym: "heterodisulfide reductase activity" BROAD [] +synonym: "soluble heterodisulfide reductase activity" RELATED [EC:1.8.98.1] +xref: EC:1.8.98.1 +xref: MetaCyc:1.8.98.1-RXN +xref: RHEA:18085 +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0051913 +name: regulation of synaptic plasticity by chemical substance +namespace: biological_process +def: "The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] +synonym: "regulation of synaptic plasticity by drug" NARROW [] +is_a: GO:0048167 ! regulation of synaptic plasticity +relationship: part_of GO:0042221 ! response to chemical + +[Term] +id: GO:0051914 +name: positive regulation of synaptic plasticity by chemical substance +namespace: biological_process +def: "The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] +synonym: "activation of synaptic plasticity by chemical substance" NARROW [] +synonym: "positive regulation of synaptic plasticity by drug" NARROW [] +synonym: "stimulation of synaptic plasticity by chemical substance" NARROW [] +synonym: "up regulation of synaptic plasticity by chemical substance" EXACT [] +synonym: "up-regulation of synaptic plasticity by chemical substance" EXACT [] +synonym: "upregulation of synaptic plasticity by chemical substance" EXACT [] +is_a: GO:0031915 ! positive regulation of synaptic plasticity +is_a: GO:0051913 ! regulation of synaptic plasticity by chemical substance + +[Term] +id: GO:0051915 +name: induction of synaptic plasticity by chemical substance +namespace: biological_process +def: "The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] +synonym: "activation of synaptic plasticity by chemical substance" EXACT [] +synonym: "activation of synaptic plasticity by drug" NARROW [] +synonym: "induction of synaptic plasticity by drug" NARROW [] +is_a: GO:0051914 ! positive regulation of synaptic plasticity by chemical substance + +[Term] +id: GO:0051916 +name: granulocyte colony-stimulating factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF." [GOC:ai] +synonym: "G-CSF binding" EXACT [] +synonym: "granulocyte colony stimulating factor binding" EXACT [] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0051917 +name: regulation of fibrinolysis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots." [GOC:ai] +is_a: GO:0030193 ! regulation of blood coagulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042730 ! fibrinolysis +relationship: regulates GO:0042730 ! fibrinolysis + +[Term] +id: GO:0051918 +name: negative regulation of fibrinolysis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots." [GOC:ai] +synonym: "down regulation of fibrinolysis" EXACT [] +synonym: "down-regulation of fibrinolysis" EXACT [] +synonym: "downregulation of fibrinolysis" EXACT [] +synonym: "inhibition of fibrinolysis" NARROW [] +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051917 ! regulation of fibrinolysis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042730 ! fibrinolysis +relationship: negatively_regulates GO:0042730 ! fibrinolysis + +[Term] +id: GO:0051919 +name: positive regulation of fibrinolysis +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots." [GOC:ai] +synonym: "activation of fibrinolysis" NARROW [] +synonym: "stimulation of fibrinolysis" NARROW [] +synonym: "up regulation of fibrinolysis" EXACT [] +synonym: "up-regulation of fibrinolysis" EXACT [] +synonym: "upregulation of fibrinolysis" EXACT [] +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0051917 ! regulation of fibrinolysis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042730 ! fibrinolysis +relationship: positively_regulates GO:0042730 ! fibrinolysis + +[Term] +id: GO:0051920 +name: peroxiredoxin activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH." [EC:1.11.1.15, RHEA:10008] +comment: Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism. +synonym: "AhpC activity" NARROW [] +synonym: "alkyl hydroperoxide reductase C22 activity" NARROW [] +synonym: "PRDX activity" EXACT [] +synonym: "Prx activity" EXACT [] +synonym: "thiol-containing-reductant:hydroperoxide oxidoreductase activity" EXACT [EC:1.11.1.15] +xref: EC:1.11.1.15 +xref: MetaCyc:1.11.1.15-RXN +xref: Reactome:R-HSA-1222431 "Peroxynitrite is reduced to nitrite by AhpC" +xref: Reactome:R-HSA-1222755 "Peroxynitrite is reduced to nitrite by Tpx" +xref: Reactome:R-HSA-1500804 "Peroxynitrite is reduced by AhpE" +xref: RHEA:10008 +is_a: GO:0016209 ! antioxidant activity +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor + +[Term] +id: GO:0051921 +name: adenosylcobyric acid synthase (glutamine-hydrolyzing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate." [EC:6.3.5.10, RHEA:23256] +synonym: "5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity" EXACT [] +synonym: "adenosylcobyric acid synthase (glutamine-hydrolysing) activity" EXACT [] +synonym: "adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.10] +synonym: "Ado-cobyric acid synthase [glutamine hydrolyzing] activity" EXACT [] +synonym: "CobQ activity" BROAD [] +synonym: "cobyric acid synthase activity" RELATED [] +xref: EC:6.3.5.10 +xref: KEGG_REACTION:R05225 +xref: MetaCyc:R345-RXN +xref: RHEA:23256 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor + +[Term] +id: GO:0051922 +name: cholesterol sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate." [PMID:12730293] +xref: EC:2.8.2 +is_a: GO:0004027 ! alcohol sulfotransferase activity + +[Term] +id: GO:0051923 +name: sulfation +namespace: biological_process +def: "The addition of a sulfate group to a molecule." [Wikipedia:Sulfation] +synonym: "phase II metabolism" BROAD [PMID:20056724] +synonym: "sulfonation" EXACT [] +synonym: "sulfur addition" EXACT [] +synonym: "sulphation" EXACT [] +synonym: "sulphur addition" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process + +[Term] +id: GO:0051924 +name: regulation of calcium ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "regulation of calcium transport" EXACT [] +is_a: GO:0010959 ! regulation of metal ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006816 ! calcium ion transport +relationship: regulates GO:0006816 ! calcium ion transport + +[Term] +id: GO:0051925 +name: obsolete regulation of calcium ion transport via voltage-gated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel." [GOC:ai] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "regulation of calcium ion transport via voltage-gated calcium channel activity" EXACT [] +synonym: "regulation of calcium transport via voltage-gated calcium channel" EXACT [] +is_obsolete: true +consider: GO:0005245 + +[Term] +id: GO:0051926 +name: negative regulation of calcium ion transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of calcium ion transport" EXACT [] +synonym: "down-regulation of calcium ion transport" EXACT [] +synonym: "downregulation of calcium ion transport" EXACT [] +synonym: "inhibition of calcium ion transport" NARROW [] +synonym: "negative regulation of calcium transport" EXACT [] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0051924 ! regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006816 ! calcium ion transport +relationship: negatively_regulates GO:0006816 ! calcium ion transport + +[Term] +id: GO:0051927 +name: obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel." [GOC:ai] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "down regulation of calcium ion transport via voltage gated calcium channel" EXACT [] +synonym: "down-regulation of calcium ion transport via voltage gated calcium channel" EXACT [] +synonym: "downregulation of calcium ion transport via voltage gated calcium channel" EXACT [] +synonym: "inhibition of calcium ion transport via voltage gated calcium channel" NARROW [] +synonym: "negative regulation of calcium ion transport via voltage-gated calcium channel activity" EXACT [] +synonym: "negative regulation of calcium transport via voltage gated calcium channel" RELATED [] +is_obsolete: true +consider: GO:0005245 + +[Term] +id: GO:0051928 +name: positive regulation of calcium ion transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of calcium ion transport" NARROW [] +synonym: "positive regulation of calcium transport" EXACT [] +synonym: "stimulation of calcium ion transport" NARROW [] +synonym: "up regulation of calcium ion transport" EXACT [] +synonym: "up-regulation of calcium ion transport" EXACT [] +synonym: "upregulation of calcium ion transport" EXACT [] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0051924 ! regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006816 ! calcium ion transport +relationship: positively_regulates GO:0006816 ! calcium ion transport + +[Term] +id: GO:0051929 +name: obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels." [GOC:ai] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "activation of calcium ion transport via voltage gated calcium channel" NARROW [] +synonym: "positive regulation of calcium ion transport via voltage-gated calcium channel activity" EXACT [] +synonym: "positive regulation of calcium transport via voltage gated calcium channel" EXACT [] +synonym: "stimulation of calcium ion transport via voltage gated calcium channel" NARROW [] +synonym: "up regulation of calcium ion transport via voltage gated calcium channel" EXACT [] +synonym: "up-regulation of calcium ion transport via voltage gated calcium channel" EXACT [] +synonym: "upregulation of calcium ion transport via voltage gated calcium channel" EXACT [] +is_obsolete: true +consider: GO:0005245 + +[Term] +id: GO:0051930 +name: regulation of sensory perception of pain +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] +is_a: GO:0051931 ! regulation of sensory perception +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019233 ! sensory perception of pain +relationship: regulates GO:0019233 ! sensory perception of pain + +[Term] +id: GO:0051931 +name: regulation of sensory perception +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] +is_a: GO:0031644 ! regulation of nervous system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007600 ! sensory perception +relationship: regulates GO:0007600 ! sensory perception + +[Term] +id: GO:0051932 +name: synaptic transmission, GABAergic +namespace: biological_process +def: "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, ISBN:0126603030] +synonym: "GABAergic synaptic transmission" EXACT [] +synonym: "synaptic transmission, GABA mediated" EXACT [] +synonym: "synaptic transmission, gamma-aminobutyric acid mediated" EXACT [] +synonym: "synaptic transmission, gamma-aminobutyric acid-ergic" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0051933 +name: amino acid neurotransmitter reuptake +namespace: biological_process +def: "The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters." [ISBN:0123668387] +synonym: "amino acid neurotransmitter import into glial cell" NARROW [] +synonym: "amino acid neurotransmitter import into neuron" NARROW [] +synonym: "amino acid neurotransmitter recycling" BROAD [] +synonym: "amino acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +is_a: GO:0043090 ! amino acid import +is_a: GO:0098810 ! neurotransmitter reuptake + +[Term] +id: GO:0051934 +name: catecholamine uptake involved in synaptic transmission +namespace: biological_process +def: "The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters." [ISBN:0123668387] +synonym: "catecholamine neurotransmitter import into glial cell" NARROW [] +synonym: "catecholamine neurotransmitter import into neuron" NARROW [] +synonym: "catecholamine neurotransmitter recycling" BROAD [] +synonym: "catecholamine neurotransmitter reuptake" EXACT [] +synonym: "catecholamine reuptake during transmission of nerve impulse" RELATED [] +synonym: "catecholamine uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +is_a: GO:0090493 ! catecholamine uptake +is_a: GO:0098810 ! neurotransmitter reuptake + +[Term] +id: GO:0051935 +name: glutamate reuptake +namespace: biological_process +def: "The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters." [ISBN:0123668387, Wikipedia:Glutamate_transporter] +synonym: "glutamate import into glial cell" NARROW [] +synonym: "glutamate import into neuron" NARROW [] +synonym: "glutamate recycling" BROAD [] +synonym: "glutamate uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "L-glutamate reuptake" EXACT [] +synonym: "L-glutamate uptake during transmission of nerve impulse" RELATED [] +synonym: "L-glutamate uptake involved in synaptic transmission" EXACT [] +is_a: GO:0051933 ! amino acid neurotransmitter reuptake +is_a: GO:0098712 ! L-glutamate import across plasma membrane + +[Term] +id: GO:0051936 +name: gamma-aminobutyric acid reuptake +namespace: biological_process +def: "The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters." [ISBN:0123668387] +synonym: "GABA import into glial cell" NARROW [] +synonym: "GABA import into neuron" NARROW [] +synonym: "GABA recycling" BROAD [] +synonym: "GABA reuptake" EXACT [] +synonym: "gamma-aminobutyric acid import into glial cell" NARROW [] +synonym: "gamma-aminobutyric acid import into neuron" NARROW [] +synonym: "gamma-aminobutyric acid recycling" BROAD [] +synonym: "gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "gamma-aminobutyric acid uptake involved in synaptic transmission" EXACT [] +is_a: GO:0015812 ! gamma-aminobutyric acid transport +is_a: GO:0051933 ! amino acid neurotransmitter reuptake + +[Term] +id: GO:0051937 +name: catecholamine transport +namespace: biological_process +def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] +is_a: GO:0015844 ! monoamine transport +is_a: GO:0015850 ! organic hydroxy compound transport + +[Term] +id: GO:0051938 +name: L-glutamate import +namespace: biological_process +def: "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle." [GOC:ai, GOC:jsg, GOC:mah] +synonym: "L-glutamate uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0043090 ! amino acid import + +[Term] +id: GO:0051939 +name: gamma-aminobutyric acid import +namespace: biological_process +def: "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle." [GOC:ai] +synonym: "4-aminobutyrate import" EXACT [] +synonym: "GABA import" EXACT [] +synonym: "gamma-aminobutyrate import" EXACT [] +synonym: "gamma-aminobutyric acid uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:0015812 ! gamma-aminobutyric acid transport +is_a: GO:0043090 ! amino acid import + +[Term] +id: GO:0051940 +name: regulation of catecholamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell." [GOC:ai] +synonym: "regulation of catecholamine neurotransmitter reuptake" EXACT [] +synonym: "regulation of catecholamine neurotransmitter uptake" EXACT [] +synonym: "regulation of catecholamine uptake during transmission of nerve impulse" BROAD [GOC:dph, GOC:tb] +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:0051952 ! regulation of amine transport +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission +relationship: regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission + +[Term] +id: GO:0051941 +name: regulation of amino acid uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell." [GOC:ai] +synonym: "regulation of amino acid neurotransmitter reuptake" EXACT [] +synonym: "regulation of amino acid neurotransmitter uptake" EXACT [] +synonym: "regulation of amino acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051933 ! amino acid neurotransmitter reuptake +relationship: regulates GO:0051933 ! amino acid neurotransmitter reuptake + +[Term] +id: GO:0051942 +name: negative regulation of amino acid uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell." [GOC:ai] +synonym: "down regulation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "down-regulation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "downregulation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "inhibition of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "negative regulation of amino acid neurotransmitter reuptake" EXACT [] +synonym: "negative regulation of amino acid neurotransmitter uptake" EXACT [] +synonym: "negative regulation of amino acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051941 ! regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051956 ! negative regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051933 ! amino acid neurotransmitter reuptake +relationship: negatively_regulates GO:0051933 ! amino acid neurotransmitter reuptake + +[Term] +id: GO:0051943 +name: positive regulation of amino acid uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell." [GOC:ai] +synonym: "activation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "positive regulation of amino acid neurotransmitter reuptake" EXACT [] +synonym: "positive regulation of amino acid neurotransmitter uptake" EXACT [] +synonym: "stimulation of amino acid uptake during transmission of nerve impulse" NARROW [] +synonym: "up regulation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "up-regulation of amino acid uptake during transmission of nerve impulse" RELATED [] +synonym: "upregulation of amino acid uptake during transmission of nerve impulse" RELATED [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051941 ! regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051957 ! positive regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051933 ! amino acid neurotransmitter reuptake +relationship: positively_regulates GO:0051933 ! amino acid neurotransmitter reuptake + +[Term] +id: GO:0051944 +name: positive regulation of catecholamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell." [GOC:ai, GOC:dph, GOC:tb] +synonym: "activation of catecholamine uptake during transmission of nerve impulse" NARROW [] +synonym: "positive regulation of catecholamine neurotransmitter reuptake" EXACT [] +synonym: "positive regulation of catecholamine neurotransmitter uptake" EXACT [] +synonym: "positive regulation of catecholamine uptake during transmission of nerve impulse" BROAD [GOC:dph, GOC:tb] +synonym: "stimulation of catecholamine uptake during transmission of nerve impulse" NARROW [] +synonym: "up regulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +synonym: "up-regulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +synonym: "upregulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051940 ! regulation of catecholamine uptake involved in synaptic transmission +is_a: GO:0051954 ! positive regulation of amine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission +relationship: positively_regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission + +[Term] +id: GO:0051945 +name: negative regulation of catecholamine uptake involved in synaptic transmission +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell." [GOC:ai, GOC:dph, GOC:tb] +synonym: "down regulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +synonym: "down-regulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +synonym: "downregulation of catecholamine uptake during transmission of nerve impulse" EXACT [] +synonym: "inhibition of catecholamine uptake during transmission of nerve impulse" NARROW [] +synonym: "negative regulation of catecholamine neurotransmitter reuptake" EXACT [] +synonym: "negative regulation of catecholamine neurotransmitter uptake" EXACT [] +synonym: "negative regulation of catecholamine uptake during transmission of nerve impulse" BROAD [GOC:dph, GOC:tb] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051940 ! regulation of catecholamine uptake involved in synaptic transmission +is_a: GO:0051953 ! negative regulation of amine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission +relationship: negatively_regulates GO:0051934 ! catecholamine uptake involved in synaptic transmission + +[Term] +id: GO:0051946 +name: regulation of glutamate uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell." [GOC:ai] +synonym: "regulation of glutamate reuptake" EXACT [] +synonym: "regulation of glutamate uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of glutamate uptake involved in conduction of nerve impulse" EXACT [GOC:dph] +synonym: "regulation of L-glutamate reuptake" EXACT [] +synonym: "regulation of L-glutamate uptake during transmission of nerve impulse" EXACT [] +is_a: GO:0002036 ! regulation of L-glutamate import across plasma membrane +is_a: GO:0051941 ! regulation of amino acid uptake involved in synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051935 ! glutamate reuptake +relationship: regulates GO:0051935 ! glutamate reuptake + +[Term] +id: GO:0051947 +name: regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai] +synonym: "regulation of 4-aminobutyrate reuptake" EXACT [] +synonym: "regulation of 4-aminobutyrate uptake during transmission of nerve impulse" EXACT [] +synonym: "regulation of GABA reuptake" EXACT [] +synonym: "regulation of GABA uptake during transmission of nerve impulse" EXACT [] +synonym: "regulation of gamma-aminobutyric acid reuptake" EXACT [] +synonym: "regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse" EXACT [GOC:dph] +is_a: GO:0051941 ! regulation of amino acid uptake involved in synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051936 ! gamma-aminobutyric acid reuptake +relationship: regulates GO:0051936 ! gamma-aminobutyric acid reuptake + +[Term] +id: GO:0051948 +name: negative regulation of glutamate uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell." [GOC:ai] +synonym: "down regulation of glutamate uptake during transmission of nerve impulse" EXACT [] +synonym: "down-regulation of glutamate uptake during transmission of nerve impulse" EXACT [] +synonym: "downregulation of glutamate uptake during transmission of nerve impulse" EXACT [] +synonym: "inhibition of glutamate uptake during transmission of nerve impulse" NARROW [] +synonym: "negative regulation of glutamate reuptake" EXACT [] +synonym: "negative regulation of glutamate uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of glutamate uptake involved in conduction of nerve impulse" RELATED [GOC:dph] +is_a: GO:0002037 ! negative regulation of L-glutamate import across plasma membrane +is_a: GO:0051942 ! negative regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051946 ! regulation of glutamate uptake involved in transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051935 ! glutamate reuptake +relationship: negatively_regulates GO:0051935 ! glutamate reuptake + +[Term] +id: GO:0051949 +name: negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai] +synonym: "down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +synonym: "down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +synonym: "downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +synonym: "inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse" NARROW [] +synonym: "negative regulation of 4-aminobutyrate reuptake" EXACT [] +synonym: "negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse" EXACT [] +synonym: "negative regulation of GABA reuptake" EXACT [] +synonym: "negative regulation of GABA uptake during transmission of nerve impulse" EXACT [] +synonym: "negative regulation of gamma-aminobutyric acid reuptake" EXACT [] +synonym: "negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse" EXACT [GOC:dph] +is_a: GO:0051942 ! negative regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051947 ! regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake +relationship: negatively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake + +[Term] +id: GO:0051950 +name: positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell." [GOC:ai] +synonym: "activation of gamma-aminobutyric acid uptake during transmission of nerve impulse" NARROW [] +synonym: "positive regulation of 4-aminobutyrate reuptake" EXACT [] +synonym: "positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse" EXACT [] +synonym: "positive regulation of GABA reuptake" EXACT [] +synonym: "positive regulation of GABA uptake during transmission of nerve impulse" EXACT [] +synonym: "positive regulation of gamma-aminobutyric acid reuptake" EXACT [] +synonym: "positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse" EXACT [GOC:dph] +synonym: "stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" NARROW [] +synonym: "up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +synonym: "up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +synonym: "upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse" EXACT [] +is_a: GO:0051943 ! positive regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051947 ! regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake +relationship: positively_regulates GO:0051936 ! gamma-aminobutyric acid reuptake + +[Term] +id: GO:0051951 +name: positive regulation of glutamate uptake involved in transmission of nerve impulse +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell." [GOC:ai] +synonym: "activation of glutamate uptake during transmission of nerve impulse" NARROW [] +synonym: "positive regulation of glutamate reuptake" EXACT [] +synonym: "positive regulation of glutamate uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of glutamate uptake involved in conduction of nerve impulse" EXACT [GOC:dph] +synonym: "stimulation of glutamate uptake during transmission of nerve impulse" NARROW [] +synonym: "up regulation of glutamate uptake during transmission of nerve impulse" EXACT [] +synonym: "up-regulation of glutamate uptake during transmission of nerve impulse" EXACT [] +synonym: "upregulation of glutamate uptake during transmission of nerve impulse" EXACT [] +is_a: GO:0002038 ! positive regulation of L-glutamate import across plasma membrane +is_a: GO:0051943 ! positive regulation of amino acid uptake involved in synaptic transmission +is_a: GO:0051946 ! regulation of glutamate uptake involved in transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051935 ! glutamate reuptake +relationship: positively_regulates GO:0051935 ! glutamate reuptake + +[Term] +id: GO:0051952 +name: regulation of amine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015837 ! amine transport +relationship: regulates GO:0015837 ! amine transport + +[Term] +id: GO:0051953 +name: negative regulation of amine transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of amine transport" EXACT [] +synonym: "down-regulation of amine transport" EXACT [] +synonym: "downregulation of amine transport" EXACT [] +synonym: "inhibition of amine transport" NARROW [] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051952 ! regulation of amine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015837 ! amine transport +relationship: negatively_regulates GO:0015837 ! amine transport + +[Term] +id: GO:0051954 +name: positive regulation of amine transport +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of amine transport" NARROW [] +synonym: "stimulation of amine transport" NARROW [] +synonym: "up regulation of amine transport" EXACT [] +synonym: "up-regulation of amine transport" EXACT [] +synonym: "upregulation of amine transport" EXACT [] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051952 ! regulation of amine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015837 ! amine transport +relationship: positively_regulates GO:0015837 ! amine transport + +[Term] +id: GO:0051955 +name: regulation of amino acid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:0044070 ! regulation of anion transport +is_a: GO:0051952 ! regulation of amine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006865 ! amino acid transport +relationship: regulates GO:0006865 ! amino acid transport + +[Term] +id: GO:0051956 +name: negative regulation of amino acid transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "down regulation of amino acid transport" EXACT [] +synonym: "down-regulation of amino acid transport" EXACT [] +synonym: "downregulation of amino acid transport" EXACT [] +synonym: "inhibition of amino acid transport" NARROW [] +synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] +is_a: GO:0032891 ! negative regulation of organic acid transport +is_a: GO:0051953 ! negative regulation of amine transport +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:1903792 ! negative regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006865 ! amino acid transport +relationship: negatively_regulates GO:0006865 ! amino acid transport + +[Term] +id: GO:0051957 +name: positive regulation of amino acid transport +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] +synonym: "activation of amino acid transport" NARROW [] +synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah] +synonym: "stimulation of amino acid transport" NARROW [] +synonym: "up regulation of amino acid transport" EXACT [] +synonym: "up-regulation of amino acid transport" EXACT [] +synonym: "upregulation of amino acid transport" EXACT [] +is_a: GO:0032892 ! positive regulation of organic acid transport +is_a: GO:0051954 ! positive regulation of amine transport +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:1903793 ! positive regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006865 ! amino acid transport +relationship: positively_regulates GO:0006865 ! amino acid transport + +[Term] +id: GO:0051958 +name: methotrexate transport +namespace: biological_process +def: "The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase." [GOC:ai] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0042886 ! amide transport + +[Term] +id: GO:0051959 +name: dynein light intermediate chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light intermediate chain of the dynein complex." [GOC:bf] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0051960 +name: regulation of nervous system development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007399 ! nervous system development +relationship: regulates GO:0007399 ! nervous system development + +[Term] +id: GO:0051961 +name: negative regulation of nervous system development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] +synonym: "down regulation of nervous system development" EXACT [] +synonym: "down-regulation of nervous system development" EXACT [] +synonym: "downregulation of nervous system development" EXACT [] +synonym: "inhibition of nervous system development" NARROW [] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007399 ! nervous system development +relationship: negatively_regulates GO:0007399 ! nervous system development + +[Term] +id: GO:0051962 +name: positive regulation of nervous system development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] +synonym: "activation of nervous system development" NARROW [] +synonym: "stimulation of nervous system development" NARROW [] +synonym: "up regulation of nervous system development" EXACT [] +synonym: "up-regulation of nervous system development" EXACT [] +synonym: "upregulation of nervous system development" EXACT [] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007399 ! nervous system development +relationship: positively_regulates GO:0007399 ! nervous system development + +[Term] +id: GO:0051963 +name: regulation of synapse assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] +subset: goslim_synapse +synonym: "regulation of synapse biogenesis" EXACT [] +synonym: "regulation of synaptogenesis" EXACT [] +is_a: GO:0050807 ! regulation of synapse organization +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007416 ! synapse assembly +relationship: regulates GO:0007416 ! synapse assembly + +[Term] +id: GO:0051964 +name: negative regulation of synapse assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] +synonym: "down regulation of synapse assembly" EXACT [] +synonym: "down-regulation of synapse assembly" EXACT [] +synonym: "downregulation of synapse assembly" EXACT [] +synonym: "inhibition of synapse assembly" NARROW [] +synonym: "negative regulation of synapse biogenesis" EXACT [] +synonym: "negative regulation of synaptogenesis" EXACT [] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:0051963 ! regulation of synapse assembly +is_a: GO:1901889 ! negative regulation of cell junction assembly +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007416 ! synapse assembly +relationship: negatively_regulates GO:0007416 ! synapse assembly + +[Term] +id: GO:0051965 +name: positive regulation of synapse assembly +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] +synonym: "activation of synapse assembly" NARROW [] +synonym: "positive regulation of synapse biogenesis" EXACT [] +synonym: "positive regulation of synaptogenesis" EXACT [] +synonym: "stimulation of synapse assembly" NARROW [] +synonym: "up regulation of synapse assembly" EXACT [] +synonym: "up-regulation of synapse assembly" EXACT [] +synonym: "upregulation of synapse assembly" EXACT [] +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:0051963 ! regulation of synapse assembly +is_a: GO:1901890 ! positive regulation of cell junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007416 ! synapse assembly +relationship: positively_regulates GO:0007416 ! synapse assembly + +[Term] +id: GO:0051966 +name: regulation of synaptic transmission, glutamatergic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035249 ! synaptic transmission, glutamatergic +relationship: regulates GO:0035249 ! synaptic transmission, glutamatergic + +[Term] +id: GO:0051967 +name: negative regulation of synaptic transmission, glutamatergic +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] +synonym: "down regulation of synaptic transmission, glutamatergic" EXACT [] +synonym: "down-regulation of synaptic transmission, glutamatergic" EXACT [] +synonym: "downregulation of synaptic transmission, glutamatergic" EXACT [] +synonym: "inhibition of synaptic transmission, glutamatergic" NARROW [] +is_a: GO:0050805 ! negative regulation of synaptic transmission +is_a: GO:0051966 ! regulation of synaptic transmission, glutamatergic +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035249 ! synaptic transmission, glutamatergic +relationship: negatively_regulates GO:0035249 ! synaptic transmission, glutamatergic + +[Term] +id: GO:0051968 +name: positive regulation of synaptic transmission, glutamatergic +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] +synonym: "activation of synaptic transmission, glutamatergic" NARROW [] +synonym: "stimulation of synaptic transmission, glutamatergic" NARROW [] +synonym: "up regulation of synaptic transmission, glutamatergic" EXACT [] +synonym: "up-regulation of synaptic transmission, glutamatergic" EXACT [] +synonym: "upregulation of synaptic transmission, glutamatergic" EXACT [] +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:0051966 ! regulation of synaptic transmission, glutamatergic +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035249 ! synaptic transmission, glutamatergic +relationship: positively_regulates GO:0035249 ! synaptic transmission, glutamatergic + +[Term] +id: GO:0051969 +name: regulation of transmission of nerve impulse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] +synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0031644 ! regulation of nervous system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019226 ! transmission of nerve impulse +relationship: regulates GO:0019226 ! transmission of nerve impulse + +[Term] +id: GO:0051970 +name: negative regulation of transmission of nerve impulse +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] +synonym: "down regulation of transmission of nerve impulse" EXACT [] +synonym: "down-regulation of transmission of nerve impulse" EXACT [] +synonym: "downregulation of transmission of nerve impulse" EXACT [] +synonym: "inhibition of transmission of nerve impulse" NARROW [] +synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0051969 ! regulation of transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019226 ! transmission of nerve impulse +relationship: negatively_regulates GO:0019226 ! transmission of nerve impulse + +[Term] +id: GO:0051971 +name: positive regulation of transmission of nerve impulse +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] +synonym: "activation of transmission of nerve impulse" NARROW [] +synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph] +synonym: "stimulation of transmission of nerve impulse" NARROW [] +synonym: "up regulation of transmission of nerve impulse" EXACT [] +synonym: "up-regulation of transmission of nerve impulse" EXACT [] +synonym: "upregulation of transmission of nerve impulse" EXACT [] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0051969 ! regulation of transmission of nerve impulse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019226 ! transmission of nerve impulse +relationship: positively_regulates GO:0019226 ! transmission of nerve impulse + +[Term] +id: GO:0051972 +name: regulation of telomerase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence." [EC:2.-.-.-, GOC:ai] +synonym: "telomerase regulator" EXACT [] +is_a: GO:0051338 ! regulation of transferase activity +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003720 ! telomerase activity +relationship: regulates GO:0003720 ! telomerase activity + +[Term] +id: GO:0051973 +name: positive regulation of telomerase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)." [GOC:ai] +synonym: "activation of telomerase activity" NARROW [] +synonym: "stimulation of telomerase activity" NARROW [] +synonym: "telomerase activator" RELATED [] +synonym: "up regulation of telomerase activity" EXACT [] +synonym: "up-regulation of telomerase activity" EXACT [] +synonym: "upregulation of telomerase activity" EXACT [] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:0051972 ! regulation of telomerase activity +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003720 ! telomerase activity +relationship: positively_regulates GO:0003720 ! telomerase activity + +[Term] +id: GO:0051974 +name: negative regulation of telomerase activity +namespace: biological_process +def: "Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)." [GOC:ai] +synonym: "down regulation of telomerase activity" EXACT [] +synonym: "down-regulation of telomerase activity" EXACT [] +synonym: "downregulation of telomerase activity" EXACT [] +synonym: "inhibition of telomerase activity" NARROW [] +synonym: "telomerase inhibitor" RELATED [] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:0051972 ! regulation of telomerase activity +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003720 ! telomerase activity +relationship: negatively_regulates GO:0003720 ! telomerase activity + +[Term] +id: GO:0051975 +name: lysine biosynthetic process via alpha-aminoadipate and saccharopine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine." [MetaCyc:LYSINE-AMINOAD-PWY] +synonym: "lysine biosynthesis via aminoadipic acid and saccharopine" EXACT [] +synonym: "lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT [] +xref: MetaCyc:LYSINE-AMINOAD-PWY +is_a: GO:0019878 ! lysine biosynthetic process via aminoadipic acid + +[Term] +id: GO:0051976 +name: lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine." [MetaCyc:PWY-3081] +synonym: "lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT [] +synonym: "lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT [] +xref: MetaCyc:PWY-3081 +is_a: GO:0019878 ! lysine biosynthetic process via aminoadipic acid + +[Term] +id: GO:0051977 +name: lysophospholipid transport +namespace: biological_process +def: "The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids." [GOC:ai] +is_a: GO:0015914 ! phospholipid transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0051978 +name: lysophospholipid:sodium symporter activity +namespace: molecular_function +def: "Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids." [GOC:ai] +synonym: "lysophospholipid transporter activity" BROAD [] +is_a: GO:0005436 ! sodium:phosphate symporter activity +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0051977 ! lysophospholipid transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17207 xsd:anyURI + +[Term] +id: GO:0051979 +name: alginic acid acetylation +namespace: biological_process +def: "The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate." [GOC:mlg] +synonym: "alginate acetylation" EXACT [] +is_a: GO:0042120 ! alginic acid metabolic process + +[Term] +id: GO:0051980 +name: iron-nicotianamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other." [GOC:ai, PMID:20625001] +synonym: "Fe-NA chelate transporter activity" EXACT [] +is_a: GO:0015603 ! iron chelate transmembrane transporter activity + +[Term] +id: GO:0051981 +name: copper chelate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions." [PMID:26512647] +is_a: GO:0005375 ! copper ion transmembrane transporter activity + +[Term] +id: GO:0051982 +name: copper-nicotianamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other." [GOC:ai] +synonym: "Cu-NA chelate transporter activity" EXACT [] +is_a: GO:0051981 ! copper chelate transmembrane transporter activity + +[Term] +id: GO:0051983 +name: regulation of chromosome segregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007059 ! chromosome segregation +relationship: regulates GO:0007059 ! chromosome segregation + +[Term] +id: GO:0051984 +name: positive regulation of chromosome segregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] +synonym: "activation of chromosome segregation" NARROW [] +synonym: "stimulation of chromosome segregation" NARROW [] +synonym: "up regulation of chromosome segregation" EXACT [] +synonym: "up-regulation of chromosome segregation" EXACT [] +synonym: "upregulation of chromosome segregation" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051983 ! regulation of chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007059 ! chromosome segregation +relationship: positively_regulates GO:0007059 ! chromosome segregation + +[Term] +id: GO:0051985 +name: negative regulation of chromosome segregation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] +synonym: "down regulation of chromosome segregation" EXACT [] +synonym: "down-regulation of chromosome segregation" EXACT [] +synonym: "downregulation of chromosome segregation" EXACT [] +synonym: "inhibition of chromosome segregation" NARROW [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051983 ! regulation of chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007059 ! chromosome segregation +relationship: negatively_regulates GO:0007059 ! chromosome segregation + +[Term] +id: GO:0051986 +name: negative regulation of attachment of spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] +synonym: "down regulation of attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "down-regulation of attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "downregulation of attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "inhibition of attachment of spindle microtubules to kinetochore" NARROW [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0051985 ! negative regulation of chromosome segregation +is_a: GO:0051988 ! regulation of attachment of spindle microtubules to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008608 ! attachment of spindle microtubules to kinetochore +relationship: negatively_regulates GO:0008608 ! attachment of spindle microtubules to kinetochore + +[Term] +id: GO:0051987 +name: positive regulation of attachment of spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] +synonym: "activation of attachment of spindle microtubules to kinetochore" NARROW [] +synonym: "stimulation of attachment of spindle microtubules to kinetochore" NARROW [] +synonym: "up regulation of attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "upregulation of attachment of spindle microtubules to kinetochore" EXACT [] +is_a: GO:0051984 ! positive regulation of chromosome segregation +is_a: GO:0051988 ! regulation of attachment of spindle microtubules to kinetochore +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008608 ! attachment of spindle microtubules to kinetochore +relationship: positively_regulates GO:0008608 ! attachment of spindle microtubules to kinetochore + +[Term] +id: GO:0051988 +name: regulation of attachment of spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] +synonym: "regulation of kinetochore-microtubule attachment" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051983 ! regulation of chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008608 ! attachment of spindle microtubules to kinetochore +relationship: regulates GO:0008608 ! attachment of spindle microtubules to kinetochore + +[Term] +id: GO:0051989 +name: coproporphyrinogen dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine." [EC:1.3.98.3] +synonym: "coproporphyrinogen III oxidase activity" EXACT [EC:1.3.98.3] +synonym: "coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)" EXACT [EC:1.3.98.3] +synonym: "HemN" RELATED [EC:1.3.98.3] +synonym: "oxygen-independent coproporphyrinogen-III oxidase activity" EXACT [] +synonym: "radical SAM enzyme activity" RELATED [EC:1.3.98.3] +xref: EC:1.3.98.3 +xref: MetaCyc:HEMN-RXN +xref: RHEA:15425 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0051990 +name: (R)-2-hydroxyglutarate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor." [EC:1.1.99.39, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN] +synonym: "D-2-hydroxyglutarate dehydrogenase activity" EXACT [] +xref: EC:1.1.99.39 +xref: Reactome:R-HSA-880007 "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2" +xref: Reactome:R-HSA-880053 "2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1]" +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0051991 +name: UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP." [MetaCyc:NACGLCTRANS-RXN] +comment: Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227. +xref: EC:2.4.1.227 +xref: MetaCyc:NACGLCTRANS-RXN +is_a: GO:0008375 ! acetylglucosaminyltransferase activity +created_by: ai +creation_date: 2010-07-06T11:53:19Z + +[Term] +id: GO:0051992 +name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol." [EC:2.7.8.13, MetaCyc:PHOSNACMURPENTATRANS-RXN] +comment: Note that EC classifies 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under the same EC number, EC:2.7.8.13. +subset: goslim_chembl +xref: EC:2.7.8.13 +xref: MetaCyc:PHOSNACMURPENTATRANS-RXN +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: ai +creation_date: 2010-07-06T12:10:01Z + +[Term] +id: GO:0051993 +name: abscisic acid glucose ester beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose." [PMID:16990135] +synonym: "ABA-GE beta-glucosidase activity" EXACT [] +xref: EC:3.2.1.175 +xref: MetaCyc:RXN-11469 +is_a: GO:0008422 ! beta-glucosidase activity +created_by: ai +creation_date: 2010-07-16T02:16:59Z + +[Term] +id: GO:0051994 +name: P-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule." [GOC:ai] +xref: EC:2.1.1 +is_a: GO:0008168 ! methyltransferase activity +created_by: ai +creation_date: 2010-07-16T04:39:34Z + +[Term] +id: GO:0051995 +name: Se-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule." [GOC:ai] +is_a: GO:0008168 ! methyltransferase activity +created_by: ai +creation_date: 2010-07-16T04:48:08Z + +[Term] +id: GO:0051996 +name: squalene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate." [EC:2.5.1.21] +comment: Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'. +synonym: "squalene synthetase activity" EXACT [EC:2.5.1.21] +xref: EC:2.5.1.21 +xref: MetaCyc:RXN66-281 +is_a: GO:0004311 ! farnesyltranstransferase activity +created_by: ai +creation_date: 2010-07-16T05:10:24Z + +[Term] +id: GO:0051997 +name: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2." [MetaCyc:RXN-6201] +synonym: "4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity" EXACT [] +synonym: "OHCU decarboxylase activity" EXACT [] +xref: KEGG_REACTION:R06604 +xref: MetaCyc:RXN-6201 +is_a: GO:0016831 ! carboxy-lyase activity +created_by: ai +creation_date: 2010-07-19T10:47:15Z + +[Term] +id: GO:0051998 +name: protein carboxyl O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group to a carboxyl group on a protein." [GOC:ai] +synonym: "protein carboxyl methyltransferase activity" EXACT [] +is_a: GO:0008276 ! protein methyltransferase activity +is_a: GO:0010340 ! carboxyl-O-methyltransferase activity +created_by: ai +creation_date: 2010-07-20T09:23:00Z + +[Term] +id: GO:0051999 +name: mannosyl-inositol phosphorylceramide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai] +synonym: "mannose inositol phosphoceramide biosynthetic process" EXACT [] +synonym: "mannose-inositol-P-ceramide (MIPC) biosynthetic process" EXACT [] +synonym: "mannosyl-inositol phosphorylceramide anabolism" EXACT [] +synonym: "mannosyl-inositol phosphorylceramide biosynthesis" EXACT [] +synonym: "mannosyl-inositol phosphorylceramide formation" EXACT [] +synonym: "mannosyl-inositol phosphorylceramide synthesis" EXACT [] +synonym: "MIPC biosynthetic process" EXACT [] +is_a: GO:0006675 ! mannosyl-inositol phosphorylceramide metabolic process +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +is_a: GO:0008654 ! phospholipid biosynthetic process +created_by: ai +creation_date: 2010-07-20T10:16:26Z + +[Term] +id: GO:0052001 +name: type IV pili-dependent localized adherence to host +namespace: biological_process +def: "Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml] +is_a: GO:0044406 ! adhesion of symbiont to host + +[Term] +id: GO:0052002 +name: metabolism by symbiont of substance in host +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052214 ! metabolism of substance in other organism involved in symbiotic interaction + +[Term] +id: GO:0052003 +name: suppression by symbiont of defense-related host salicylic acid-mediated signal transduction pathway +namespace: biological_process +alt_id: GO:0052004 +alt_id: GO:0052252 +alt_id: GO:0052253 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "down regulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "down-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "down-regulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "downregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "downregulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "inhibition by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "inhibition by symbiont of host salicylic acid-mediated defense response" NARROW [] +synonym: "negative modulation by organism of defense-related host SA-mediated signal transduction pathway" EXACT [] +synonym: "negative modulation by organism of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related host SA-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "negative regulation of host SA-mediated defense response" EXACT [] +synonym: "suppression by organism of host salicylic acid-mediated defense response" EXACT [] +synonym: "suppression of host SA mediated defense response" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0010113 ! negative regulation of systemic acquired resistance +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +is_a: GO:0052081 ! modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway +is_a: GO:0052089 ! modulation by symbiont of host salicylic acid-mediated defense response +is_a: GO:2001039 ! negative regulation of cellular response to drug +relationship: negatively_regulates GO:0009862 ! systemic acquired resistance, salicylic acid mediated signaling pathway + +[Term] +id: GO:0052005 +name: suppression by symbiont of host ethylene-mediated defense response +namespace: biological_process +alt_id: GO:0052070 +alt_id: GO:0052254 +alt_id: GO:0052268 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "down-regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "downregulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "inhibition by symbiont of host ethylene-mediated defense response" NARROW [] +synonym: "negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway" BROAD [] +synonym: "negative regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "suppression by organism of host ethylene-mediated defense response" EXACT [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052084 ! modulation by symbiont of host ethylene-mediated defense response + +[Term] +id: GO:0052006 +name: catabolism by symbiont of substance in host +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of substance in host" EXACT [] +is_a: GO:0052002 ! metabolism by symbiont of substance in host +is_a: GO:0052227 ! catabolism of substance in other organism involved in symbiotic interaction + +[Term] +id: GO:0052007 +name: obsolete biosynthesis by symbiont of substance in host +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "biosynthesis by organism of substance in host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18787 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052008 +name: disruption by symbiont of host cellular component +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism of host cellular component by organism" EXACT [] +synonym: "catabolism of host structural constituent by organism" EXACT [] +synonym: "degradation of host cellular component by organism" EXACT [] +synonym: "disassembly by organism of host cellular component" EXACT [] +synonym: "disassembly by symbiont of host cellular component" RELATED [] +is_a: GO:0052043 ! modification by symbiont of host cellular component +is_a: GO:0052368 ! disruption by organism of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052009 +name: disruption by symbiont of host cell wall +namespace: biological_process +def: "A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "disassembly by symbiont of host cell wall" EXACT [] +is_a: GO:0098933 ! disruption by symbiont of host cell envelope + +[Term] +id: GO:0052010 +name: catabolism by symbiont of host cell wall cellulose +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host cell wall cellulose" EXACT [] +is_a: GO:0052015 ! catabolism by symbiont of host carbohydrate +is_a: GO:0052172 ! metabolism by symbiont of host cell wall cellulose +is_a: GO:0052340 ! catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction +relationship: part_of GO:0052009 ! disruption by symbiont of host cell wall + +[Term] +id: GO:0052011 +name: catabolism by symbiont of host cell wall pectin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host cell wall pectin" EXACT [] +is_a: GO:0052015 ! catabolism by symbiont of host carbohydrate +is_a: GO:0052179 ! metabolism by symbiont of host cell wall pectin +is_a: GO:0052341 ! catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction +relationship: part_of GO:0052009 ! disruption by symbiont of host cell wall + +[Term] +id: GO:0052012 +name: catabolism by symbiont of host cell wall chitin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host cell wall chitin" EXACT [] +is_a: GO:0052015 ! catabolism by symbiont of host carbohydrate +is_a: GO:0052178 ! metabolism by symbiont of host cell wall chitin +is_a: GO:0052342 ! catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction +relationship: part_of GO:0052009 ! disruption by symbiont of host cell wall + +[Term] +id: GO:0052013 +name: catabolism by symbiont of host macromolecule +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host macromolecule" EXACT [] +is_a: GO:0052006 ! catabolism by symbiont of substance in host +is_a: GO:0052174 ! metabolism by symbiont of host macromolecule +is_a: GO:0052361 ! catabolism by organism of macromolecule in other organism involved in symbiotic interaction + +[Term] +id: GO:0052014 +name: catabolism by symbiont of host protein +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host protein" EXACT [] +is_a: GO:0052013 ! catabolism by symbiont of host macromolecule +is_a: GO:0052228 ! metabolism by symbiont of host protein +is_a: GO:0052363 ! catabolism by organism of protein in other organism involved in symbiotic interaction + +[Term] +id: GO:0052015 +name: catabolism by symbiont of host carbohydrate +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host carbohydrate" EXACT [] +is_a: GO:0052013 ! catabolism by symbiont of host macromolecule +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052016 +name: catabolism by symbiont of host glucan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host glucan" EXACT [] +is_a: GO:0052015 ! catabolism by symbiont of host carbohydrate +is_a: GO:0052176 ! metabolism by symbiont of host glucan +is_a: GO:0052359 ! catabolism by organism of glucan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052017 +name: catabolism by symbiont of host xylan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of host xylan" EXACT [] +is_a: GO:0052015 ! catabolism by symbiont of host carbohydrate +is_a: GO:0052177 ! metabolism by symbiont of host xylan +is_a: GO:0052366 ! catabolism by organism of xylan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052018 +name: modulation by symbiont of RNA levels in host +namespace: biological_process +def: "The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by symbiont of host RNA levels" EXACT [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052249 ! modulation of RNA levels in other organism involved in symbiotic interaction + +[Term] +id: GO:0052019 +name: modulation by symbiont of host hormone or growth regulator levels +namespace: biological_process +alt_id: GO:0052186 +def: "The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0044003 ! modulation by symbiont of host process + +[Term] +id: GO:0052020 +name: modification by symbiont of host cell wall +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "metabolism of host cell wall by organism" EXACT [] +is_a: GO:0052043 ! modification by symbiont of host cellular component +is_a: GO:0052333 ! modification by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052021 +name: modulation by symbiont of ethylene levels in host +namespace: biological_process +alt_id: GO:0052449 +def: "The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of ethylene levels in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0052022 +name: modulation by symbiont of jasmonic acid levels in host +namespace: biological_process +alt_id: GO:0052456 +def: "The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0052023 +name: modulation by symbiont of salicylic acid levels in host +namespace: biological_process +alt_id: GO:0052469 +def: "The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0052024 +name: positive regulation by symbiont of hormone or growth regulator levels in host +namespace: biological_process +alt_id: GO:0052513 +def: "The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of hormone or growth regulator levels in host" NARROW [] +synonym: "positive modulation of hormone or growth regulator levels in host" EXACT [] +synonym: "positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction" BROAD [] +synonym: "stimulation by symbiont of hormone or growth regulator levels in host" NARROW [] +synonym: "up regulation by symbiont of hormone or growth regulator levels in host" EXACT [] +synonym: "up-regulation by symbiont of hormone or growth regulator levels in host" EXACT [] +synonym: "upregulation by symbiont of hormone or growth regulator levels in host" EXACT [] +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0052025 +name: modification by symbiont of host cell membrane +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification by symbiont of host cell membrane" NARROW [GOC:bf, GOC:jl] +is_a: GO:0052043 ! modification by symbiont of host cellular component +is_a: GO:0052332 ! modification by organism of membrane in other organism involved in symbiotic interaction + +[Term] +id: GO:0052026 +name: modulation by symbiont of host transcription +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0052312 ! modulation of transcription in other organism involved in symbiotic interaction + +[Term] +id: GO:0052027 +name: modulation by symbiont of host signal transduction pathway +namespace: biological_process +alt_id: GO:0052250 +def: "Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by symbiont of host signal transduction" RELATED [] +synonym: "modulation of host signal transduction by symbiont" EXACT [] +synonym: "modulation of signal transduction in other organism involved in symbiotic interaction" BROAD [] +synonym: "regulation by symbiont of host signal transduction pathway" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0044501 ! modulation of signal transduction in other organism + +[Term] +id: GO:0052028 +name: induction by symbiont of host signal transduction pathway +namespace: biological_process +alt_id: GO:0044502 +alt_id: GO:0052526 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of signal transduction in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "positive regulation of signal transduction in other organism" BROAD [] +synonym: "stimulation by symbiont of host signal transduction pathway" NARROW [] +synonym: "up regulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "up-regulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "upregulation by symbiont of host signal transduction pathway" EXACT [] +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0052029 +name: suppression by symbiont of host signal transduction pathway +namespace: biological_process +alt_id: GO:0052493 +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "down-regulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "downregulation by symbiont of host signal transduction pathway" EXACT [] +synonym: "inhibition by symbiont of host signal transduction pathway" NARROW [] +synonym: "negative modulation by organism of host signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of signal transduction in other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of host signal transduction pathway" EXACT [] +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0052031 +name: modulation by symbiont of host defense response +namespace: biological_process +alt_id: GO:0052255 +def: "Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "mitigation by symbiont of host defense response" EXACT [] +synonym: "modulation by organism of defense response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052200 ! response to host defenses + +[Term] +id: GO:0052032 +name: modulation by symbiont of host inflammatory response +namespace: biological_process +alt_id: GO:0052256 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of inflammatory response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0052033 +name: obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response +namespace: biological_process +def: "OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mah] +comment: This term was obsoleted because it has been misused. +synonym: "general elicitor-dependent activation of host innate immunity" EXACT [] +synonym: "general elicitor-dependent induction of host innate immunity" EXACT [] +synonym: "MAMP dependent activation of host innate immunity" EXACT [] +synonym: "MAMP dependent induction of host innate immunity" EXACT [] +synonym: "PAMP dependent activation of host innate immunity" EXACT [] +synonym: "PAMP dependent induction of host innate immunity" EXACT [] +synonym: "pathogen-associated molecular pattern dependent activation by organism of host innate immunity" EXACT [] +synonym: "pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity" EXACT [GOC:pg] +synonym: "pattern-triggered immunity" RELATED [GOC:tb] +synonym: "PTI" RELATED [GOC:tb] +is_obsolete: true +consider: GO:0002221 +consider: GO:0002752 +consider: GO:0052034 + +[Term] +id: GO:0052034 +name: suppression by symbiont of microbe-associated molecular pattern-induced host innate immune response +namespace: biological_process +alt_id: GO:0052258 +def: "Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mah] +synonym: "down regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity" EXACT [] +synonym: "down-regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity" EXACT [] +synonym: "downregulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity" EXACT [] +synonym: "inhibition by symbiont of pathogen-associated molecular pattern-induced host innate immunity" NARROW [] +synonym: "negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response" EXACT [] +synonym: "negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immunity" EXACT [] +synonym: "suppression of general elicitor induced host innate immunity" EXACT [] +synonym: "suppression of general elicitor-induced host innate immunity" EXACT [] +synonym: "suppression of MAMP induced host innate immunity" EXACT [] +synonym: "suppression of MAMP-induced host innate immunity" EXACT [] +synonym: "suppression of PAMP induced host innate immunity" EXACT [] +synonym: "suppression of PAMP-induced host innate immunity" EXACT [] +synonym: "suppression of pathogen-associated molecular pattern-induced host innate immunity" EXACT [] +is_a: GO:0052170 ! suppression by symbiont of host innate immune response + +[Term] +id: GO:0052035 +name: positive regulation by symbiont of host inflammatory response +namespace: biological_process +alt_id: GO:0052259 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host inflammatory response" NARROW [] +synonym: "positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction" BROAD [] +synonym: "stimulation by symbiont of host inflammatory response" NARROW [] +synonym: "up regulation by symbiont of host inflammatory response" EXACT [] +synonym: "up-regulation by symbiont of host inflammatory response" EXACT [] +synonym: "upregulation by symbiont of host inflammatory response" EXACT [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052032 ! modulation by symbiont of host inflammatory response + +[Term] +id: GO:0052036 +name: suppression by symbiont of host inflammatory response +namespace: biological_process +alt_id: GO:0052260 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host inflammatory response" EXACT [] +synonym: "down-regulation by symbiont of host inflammatory response" EXACT [] +synonym: "downregulation by symbiont of host inflammatory response" EXACT [] +synonym: "inhibition by symbiont of host inflammatory response" NARROW [] +synonym: "negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of host inflammatory response" EXACT [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052032 ! modulation by symbiont of host inflammatory response + +[Term] +id: GO:0052038 +name: modulation by symbiont of host intracellular transport +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of host intracellular trafficking" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0052230 ! modulation of intracellular transport in other organism involved in symbiotic interaction +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: regulates GO:0046907 ! intracellular transport + +[Term] +id: GO:0052039 +name: modification by symbiont of host cytoskeleton +namespace: biological_process +alt_id: GO:0044054 +def: "The process in which an organism effects a change in the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "rounding by symbiont of host cells" NARROW [] +is_a: GO:0052043 ! modification by symbiont of host cellular component +is_a: GO:0052334 ! modification by organism of cytoskeleton of other organism involved in symbiotic interaction + +[Term] +id: GO:0052040 +name: modulation by symbiont of host programmed cell death +namespace: biological_process +alt_id: GO:0052152 +def: "Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by symbiont of host non-apoptotic programmed cell death" NARROW [] +synonym: "modulation of host PCD" EXACT [] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0012501 ! programmed cell death + +[Term] +id: GO:0052041 +name: negative regulation by symbiont of host programmed cell death +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host programmed cell death" EXACT [] +synonym: "down-regulation by symbiont of host programmed cell death" EXACT [] +synonym: "downregulation by symbiont of host programmed cell death" EXACT [] +synonym: "inhibition by symbiont of host programmed cell death" NARROW [] +synonym: "inhibition of host programmed cell death" EXACT [] +synonym: "suppression by symbiont of host PCD" EXACT [] +synonym: "suppression by symbiont of host programmed cell death" EXACT [] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0052040 ! modulation by symbiont of host programmed cell death +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: negatively_regulates GO:0012501 ! programmed cell death + +[Term] +id: GO:0052042 +name: positive regulation by symbiont of host programmed cell death +namespace: biological_process +alt_id: GO:0012504 +alt_id: GO:0052044 +alt_id: GO:0052045 +alt_id: GO:0052153 +alt_id: GO:0052397 +alt_id: GO:0052400 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of host programmed cell death" EXACT [] +synonym: "activation by organism of non-apoptotic programmed cell death in other organism" NARROW [] +synonym: "activation by organism of programmed cell death in other organism during symbiotic interaction" EXACT [] +synonym: "activation by symbiont of host programmed cell death" NARROW [] +synonym: "enhancement of host programmed cell death" EXACT [] +synonym: "enhancement of host programmed cell death by organism" EXACT [] +synonym: "induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "induction by organism of programmed cell death in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "induction by organism of programmed cell death in other organism involved in symbiotic interaction" EXACT [] +synonym: "induction by symbiont of host programmed cell death" EXACT [] +synonym: "induction of non-apoptotic programmed cell death by other organism" RELATED [] +synonym: "positive regulation by symbiont of host non-apoptotic programmed cell death" NARROW [] +synonym: "stimulation by symbiont of host programmed cell death" NARROW [] +synonym: "upregulation by symbiont of host programmed cell death" EXACT [] +is_a: GO:0052040 ! modulation by symbiont of host programmed cell death +is_a: GO:0052330 ! positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: positively_regulates GO:0012501 ! programmed cell death +relationship: part_of GO:0001907 ! killing by symbiont of host cells + +[Term] +id: GO:0052043 +name: modification by symbiont of host cellular component +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052111 ! modification by symbiont of host structure +is_a: GO:0052188 ! modification of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052046 +name: obsolete modification by symbiont of host morphology or physiology via secreted substance +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification of host morphology or physiology via effector molecule" NARROW [] +synonym: "modification of host morphology or physiology via ellicitor" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052047 +name: obsolete symbiotic process mediated by secreted substance +namespace: biological_process +def: "OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it has been misused to annotate host proteins. +synonym: "interaction with other organism via secreted substance during symbiotic interaction" RELATED [GOC:dph] +synonym: "interaction with other organism via secreted substance involved in symbiotic interaction" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052048 +name: obsolete interaction with host via secreted substance +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process. +synonym: "interaction with host via secreted substance during symbiotic interaction" RELATED [GOC:dph] +synonym: "interaction with host via secreted substance involved in symbiotic interaction" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052049 +name: obsolete interaction with host via protein secreted by type III secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052050 +name: obsolete interaction with host via substance secreted by type IV secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052051 +name: obsolete interaction with host via protein secreted by type II secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052052 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type II secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052053 +name: negative regulation by symbiont of host catalytic activity +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host enzyme activity" EXACT [] +synonym: "down-regulation by symbiont of host enzyme activity" EXACT [] +synonym: "downregulation by symbiont of host enzyme activity" EXACT [] +synonym: "inhibition by symbiont of host enzyme activity" NARROW [] +synonym: "inhibition of host enzyme activity" EXACT [] +synonym: "negative regulation by symbiont of host enzyme activity" EXACT [] +is_a: GO:0052056 ! negative regulation by symbiont of host molecular function +is_a: GO:0052148 ! modulation by symbiont of host catalytic activity +is_a: GO:0052199 ! negative regulation of catalytic activity in other organism involved in symbiotic interaction +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: negatively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0052054 +name: negative regulation by symbiont of host peptidase activity +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation by symbiont of host protease activity" NARROW [] +synonym: "down-regulation by symbiont of host protease activity" NARROW [] +synonym: "downregulation by symbiont of host protease activity" NARROW [] +synonym: "inhibition by symbiont of host protease activity" NARROW [] +synonym: "inhibition of host protease activity" NARROW [] +synonym: "negative regulation by symbiont of host protease activity" NARROW [GOC:dph, GOC:tb] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0052053 ! negative regulation by symbiont of host catalytic activity +is_a: GO:0052149 ! modulation by symbiont of host peptidase activity +is_a: GO:0052180 ! negative regulation of peptidase activity in other organism involved in symbiotic interaction +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: negatively_regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0052055 +name: modulation by symbiont of host molecular function +namespace: biological_process +def: "The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modification by symbiont of host molecular function" EXACT [] +synonym: "modification by symbiont of host protein function" EXACT [GOC:dph, GOC:tb] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052205 ! modulation of molecular function in other organism involved in symbiotic interaction +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0003674 ! molecular_function + +[Term] +id: GO:0052056 +name: negative regulation by symbiont of host molecular function +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation by symbiont of host protein function" EXACT [] +synonym: "down-regulation by symbiont of host protein function" EXACT [] +synonym: "downregulation by symbiont of host protein function" EXACT [] +synonym: "inhibition by symbiont of host protein function" NARROW [] +synonym: "inhibition of host protein function" EXACT [] +synonym: "negative regulation by symbiont of host protein function" EXACT [GOC:dph, GOC:tb] +is_a: GO:0052055 ! modulation by symbiont of host molecular function +is_a: GO:0052204 ! negative regulation of molecular function in other organism involved in symbiotic interaction +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: negatively_regulates GO:0003674 ! molecular_function + +[Term] +id: GO:0052057 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type III secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052058 +name: obsolete modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052062 +name: induction by symbiont of host phytoalexin production +namespace: biological_process +alt_id: GO:0052262 +def: "The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of host phytoalexin production" EXACT [] +synonym: "induction by organism of phytoalexin production in other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052063 +name: induction by symbiont of defense-related host nitric oxide production +namespace: biological_process +alt_id: GO:0052263 +alt_id: GO:0052345 +alt_id: GO:0052347 +def: "The activation by a symbiont of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of defense-related host nitric oxide production" EXACT [] +synonym: "activation by organism of defense-related host NO production" EXACT [] +synonym: "activation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "induction by organism of defense-related host NO production" EXACT [] +synonym: "induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction" RELATED [] +synonym: "positive regulation by organism of defense-related host NO production" RELATED [] +synonym: "positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "stimulation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "up regulation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "up-regulation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "upregulation by symbiont of defense-related host nitric oxide production" RELATED [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052064 +name: induction by symbiont of defense-related host reactive oxygen species production +namespace: biological_process +alt_id: GO:0052264 +alt_id: GO:0052348 +alt_id: GO:0052369 +def: "The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of defense-related host metabolic burst" EXACT [] +synonym: "activation by symbiont of defense-related host oxidative burst" EXACT [] +synonym: "activation by symbiont of defense-related host reactive oxidative species production" EXACT [] +synonym: "activation by symbiont of defense-related host reactive oxygen intermediate production" EXACT [] +synonym: "activation by symbiont of defense-related host reactive oxygen species production" EXACT [] +synonym: "activation by symbiont of defense-related host respiratory burst" EXACT [] +synonym: "activation by symbiont of defense-related host ROI production" EXACT [] +synonym: "activation by symbiont of defense-related host ROS production" EXACT [] +synonym: "induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by symbiont of defense-related host active oxygen species production" EXACT [] +synonym: "induction by symbiont of defense-related host AOS production" EXACT [] +synonym: "induction by symbiont of defense-related host metabolic burst" EXACT [] +synonym: "induction by symbiont of defense-related host oxidative burst" EXACT [] +synonym: "induction by symbiont of defense-related host reactive oxidative species production" EXACT [] +synonym: "induction by symbiont of defense-related reactive oxygen species production in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +synonym: "stimulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +synonym: "up regulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +synonym: "up-regulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +synonym: "upregulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052066 +name: obsolete entry of symbiont into host cell by promotion of host phagocytosis +namespace: biological_process +def: "OBSOLETE. The invasion by a symbiont of a host organism cell by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it was misused. +synonym: "entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction" RELATED [] +synonym: "entry of organism into host cell by promotion of host phagocytosis" EXACT [] +synonym: "penetration of organism into host cell by promotion of host phagocytosis" EXACT [GOC:vw] +synonym: "penetration of symbiont into host cell by promotion of host phagocytosis" EXACT [GOC:vw] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052067 +name: antiphagocytosis +namespace: biological_process +alt_id: GO:0052380 +alt_id: GO:0052483 +def: "Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, PMID:23084912, PMID:29114249] +synonym: "down regulation by symbiont of entry into host cell via phagocytosis" RELATED [] +synonym: "down-regulation by symbiont of entry into host cell via phagocytosis" RELATED [] +synonym: "downregulation by symbiont of entry into host cell via phagocytosis" RELATED [] +synonym: "inhibition by symbiont of entry into host cell via phagocytosis" NARROW [] +synonym: "modulation by organism of entry into host via host phagocytosis" BROAD [] +synonym: "modulation by symbiont of entry into host via phagocytosis" BROAD [] +synonym: "negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction" RELATED [] +synonym: "negative regulation by organism of entry into host cell via host phagocytosis" RELATED [] +synonym: "negative regulation by symbiont of entry into host cell via phagocytosis" RELATED [] +synonym: "phagocytosis avoidence" EXACT [] +is_a: GO:0030682 ! mitigation of host defenses by symbiont +is_a: GO:0052372 ! modulation by symbiont of entry into host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17983 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI + +[Term] +id: GO:0052072 +name: induction by symbiont of defense-related host salicylic acid-mediated signal transduction pathway +namespace: biological_process +alt_id: GO:0052270 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "activation by organism of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "activation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "stimulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "up regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "up-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by organism of defense-related host salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway" EXACT [] +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0052074 ! positive regulation by symbiont of host salicylic acid-mediated defense response +is_a: GO:0052081 ! modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway + +[Term] +id: GO:0052074 +name: positive regulation by symbiont of host salicylic acid-mediated defense response +namespace: biological_process +alt_id: GO:0052272 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host salicylic acid-mediated defense response" NARROW [] +synonym: "induction by organism of host SA-mediated defense response" NARROW [] +synonym: "induction by organism of host salicylic acid-mediated defense response" NARROW [] +synonym: "positive regulation by organism of host SA-mediated defense response" EXACT [] +synonym: "positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "stimulation by symbiont of host salicylic acid-mediated defense response" NARROW [] +synonym: "up regulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "up-regulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +synonym: "upregulation by symbiont of host salicylic acid-mediated defense response" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052089 ! modulation by symbiont of host salicylic acid-mediated defense response +is_a: GO:1901672 ! positive regulation of systemic acquired resistance +is_a: GO:2001040 ! positive regulation of cellular response to drug +relationship: positively_regulates GO:0009862 ! systemic acquired resistance, salicylic acid mediated signaling pathway + +[Term] +id: GO:0052075 +name: positive regulation by symbiont of host jasmonic acid-mediated defense response +namespace: biological_process +alt_id: GO:0052273 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "induction by organism of host JA-mediated defense response" NARROW [] +synonym: "induction by organism of host jasmonic acid-mediated defense response" NARROW [] +synonym: "positive regulation by organism of host JA-mediated defense response" EXACT [] +synonym: "positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "stimulation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "up regulation by symbiont of host jasmonic acid-mediated defense response" EXACT [] +synonym: "up-regulation by symbiont of host jasmonic acid-mediated defense response" EXACT [] +synonym: "upregulation by symbiont of host jasmonic acid-mediated defense response" EXACT [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052076 +name: induction by symbiont of host ethylene-mediated defense response +namespace: biological_process +alt_id: GO:0052071 +alt_id: GO:0052269 +alt_id: GO:0052274 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host ethylene-mediated defense response" NARROW [] +synonym: "positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway" BROAD [] +synonym: "positive regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "stimulation by symbiont of host ethylene-mediated defense response" NARROW [] +synonym: "up regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "up-regulation by symbiont of host ethylene-mediated defense response" EXACT [] +synonym: "upregulation by symbiont of host ethylene-mediated defense response" EXACT [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0052084 ! modulation by symbiont of host ethylene-mediated defense response + +[Term] +id: GO:0052078 +name: suppression by symbiont of defense-related host MAP kinase-mediated signal transduction pathway +namespace: biological_process +alt_id: GO:0052275 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "down-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "downregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "inhibition by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "negative regulation by organism of defense-related host MAPK-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "suppression by organism of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052080 ! modulation by symbiont of host innate immune response MAPK kinase signaling +is_a: GO:0075132 ! suppression by symbiont of host protein kinase-mediated signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19235 xsd:anyURI + +[Term] +id: GO:0052079 +name: induction by symbiont of defense-related host MAP kinase-mediated signal transduction pathway +namespace: biological_process +alt_id: GO:0052276 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "activation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related host MAPK-mediated signal transduction pathway" EXACT [] +synonym: "positive regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway" EXACT [] +synonym: "positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "stimulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "up regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "up-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related host MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" EXACT [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052080 ! modulation by symbiont of host innate immune response MAPK kinase signaling +is_a: GO:0075131 ! induction by symbiont of host protein kinase-mediated signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19235 xsd:anyURI + +[Term] +id: GO:0052080 +name: modulation by symbiont of host innate immune response MAPK kinase signaling +namespace: biological_process +alt_id: GO:0052277 +def: "Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway" RELATED [] +synonym: "modulation of defense-related host MAPK-mediated signal transduction pathway by organism" EXACT [] +synonym: "modulation of defense-related host mitogen activated protein kinase-mediated signal transduction pathway by organism" EXACT [] +is_a: GO:0052031 ! modulation by symbiont of host defense response +is_a: GO:0075130 ! modulation by symbiont of host protein kinase-mediated signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19235 xsd:anyURI + +[Term] +id: GO:0052081 +name: modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway +namespace: biological_process +alt_id: GO:0052445 +def: "Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation of defense-related host SA-mediated signal transduction pathway by organism" EXACT [] +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0052083 +name: suppression by symbiont of host cell-mediated immune response +namespace: biological_process +alt_id: GO:0052278 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host cell-mediated immune response" EXACT [] +synonym: "down-regulation by symbiont of host cell-mediated immune response" EXACT [] +synonym: "downregulation by symbiont of host cell-mediated immune response" EXACT [] +synonym: "inhibition by symbiont of host cell-mediated immune response" NARROW [] +synonym: "negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by organism of host cell-based immune response" EXACT [] +is_a: GO:0052155 ! modulation by symbiont of host cell-mediated immune response +is_a: GO:0052562 ! suppression by symbiont of host immune response + +[Term] +id: GO:0052084 +name: modulation by symbiont of host ethylene-mediated defense response +namespace: biological_process +alt_id: GO:0052077 +alt_id: GO:0052279 +alt_id: GO:0052441 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway" BROAD [] +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0052085 +name: suppression by symbiont of host T-cell mediated immune response +namespace: biological_process +alt_id: GO:0052280 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host T-cell mediated immune response" EXACT [] +synonym: "down-regulation by symbiont of host T-cell mediated immune response" EXACT [] +synonym: "downregulation by symbiont of host T-cell mediated immune response" EXACT [] +synonym: "inhibition by symbiont of host T-cell mediated immune response" NARROW [] +synonym: "negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of host T-cell mediated immune response" EXACT [] +is_a: GO:0052083 ! suppression by symbiont of host cell-mediated immune response +is_a: GO:0052156 ! modulation by symbiont of host T-cell mediated immune response + +[Term] +id: GO:0052086 +name: suppression by symbiont of host B-cell mediated immune response +namespace: biological_process +alt_id: GO:0052281 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host B-cell mediated immune response" EXACT [] +synonym: "down-regulation by symbiont of host B-cell mediated immune response" EXACT [] +synonym: "downregulation by symbiont of host B-cell mediated immune response" EXACT [] +synonym: "inhibition by symbiont of host B-cell mediated immune response" NARROW [] +synonym: "negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052083 ! suppression by symbiont of host cell-mediated immune response +is_a: GO:0052154 ! modulation by symbiont of host B-cell mediated immune response + +[Term] +id: GO:0052088 +name: symbiont defense to host-produced jasmonic acid +namespace: biological_process +alt_id: GO:0052068 +alt_id: GO:0052069 +alt_id: GO:0052073 +alt_id: GO:0052082 +alt_id: GO:0052266 +alt_id: GO:0052267 +alt_id: GO:0052271 +alt_id: GO:0052283 +alt_id: GO:0052443 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "activation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "down regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "down-regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "downregulation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "inhibition by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [] +synonym: "modulation by organism of host JA-mediated defense response" NARROW [] +synonym: "modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [] +synonym: "modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [] +synonym: "negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [] +synonym: "negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "negative regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [] +synonym: "positive regulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [] +synonym: "positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "suppression by organism of host JA-mediated defense response" EXACT [] +synonym: "suppression by symbiont of host jasmonic acid-mediated defense response" RELATED [] +synonym: "up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [] +is_a: GO:0042783 ! evasion of host immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18798 xsd:anyURI + +[Term] +id: GO:0052089 +name: modulation by symbiont of host salicylic acid-mediated defense response +namespace: biological_process +alt_id: GO:0052284 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of host SA-mediated defense response" EXACT [] +synonym: "modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0010112 ! regulation of systemic acquired resistance +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0052031 ! modulation by symbiont of host defense response +is_a: GO:2000031 ! regulation of salicylic acid mediated signaling pathway +relationship: regulates GO:0009862 ! systemic acquired resistance, salicylic acid mediated signaling pathway + +[Term] +id: GO:0052091 +name: modulation by symbiont of nutrient release from host +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052313 ! modulation of nutrient release from other organism involved in symbiotic interaction +relationship: part_of GO:0044002 ! acquisition of nutrients from host + +[Term] +id: GO:0052092 +name: positive regulation by symbiont of nutrient release from host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of nutrient release from host" NARROW [] +synonym: "promotion of nutrient release from host" EXACT [] +synonym: "stimulation by symbiont of nutrient release from host" NARROW [] +synonym: "up regulation by symbiont of nutrient release from host" EXACT [] +synonym: "up-regulation by symbiont of nutrient release from host" EXACT [] +synonym: "upregulation by symbiont of nutrient release from host" EXACT [] +is_a: GO:0052091 ! modulation by symbiont of nutrient release from host +is_a: GO:0052520 ! positive regulation by organism of nutrient release from other organism involved in symbiotic interaction + +[Term] +id: GO:0052093 +name: formation of specialized structure for nutrient acquisition from host +namespace: biological_process +def: "The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "formation by organism of specialized structure for nutrient acquisition from host" EXACT [] +synonym: "formation by symbiont of specialized structure for nutrient acquisition from host" EXACT [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +is_a: GO:0052095 ! formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction +relationship: part_of GO:0044002 ! acquisition of nutrients from host + +[Term] +id: GO:0052094 +name: formation by symbiont of haustorium for nutrient acquisition from host +namespace: biological_process +def: "The assembly by an organism of a haustorium, a projection from a cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "formation by organism of haustoria for nutrient acquisition from host" EXACT [] +synonym: "formation by organism of haustorium for nutrient acquisition from host" EXACT [] +is_a: GO:0044118 ! development of symbiont in host cell +is_a: GO:0052093 ! formation of specialized structure for nutrient acquisition from host + +[Term] +id: GO:0052095 +name: formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction +namespace: biological_process +def: "The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "formation of specialized structure for nutrient acquisition from other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044111 ! development involved in symbiotic interaction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0051816 ! acquisition of nutrients from other organism during symbiotic interaction + +[Term] +id: GO:0052096 +name: formation by symbiont of syncytium involving giant cell for nutrient acquisition from host +namespace: biological_process +def: "The assembly by an organism of a syncytium, a nematode-induced multi-nucleate and physiologically active aggregation of fused root cells which exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "formation by organism of syncytium involving giant cell for nutrient acquisition from host" EXACT [] +is_a: GO:0052093 ! formation of specialized structure for nutrient acquisition from host + +[Term] +id: GO:0052097 +name: obsolete interspecies quorum sensing +namespace: biological_process +def: "OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that this term was an unnecessary grouping term. +is_obsolete: true + +[Term] +id: GO:0052098 +name: formation by host of specialized structure for nutrient acquisition from symbiont +namespace: biological_process +def: "The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052095 ! formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction +relationship: part_of GO:0051850 ! acquisition of nutrients from symbiont + +[Term] +id: GO:0052100 +name: obsolete intraspecies quorum sensing +namespace: biological_process +def: "OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that this term was an unnecessary grouping term. +is_obsolete: true + +[Term] +id: GO:0052102 +name: positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway +namespace: biological_process +alt_id: GO:0052287 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of defense-related host calcium-dependent protein kinase pathway" NARROW [] +synonym: "positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation of defense-related host CDPK pathway by organism" EXACT [] +synonym: "stimulation by symbiont of defense-related host calcium-dependent protein kinase pathway" NARROW [] +synonym: "up regulation by symbiont of defense-related host calcium-dependent protein kinase pathway" EXACT [] +synonym: "up-regulation by symbiont of defense-related host calcium-dependent protein kinase pathway" EXACT [] +synonym: "upregulation by symbiont of defense-related host calcium-dependent protein kinase pathway" EXACT [] +is_a: GO:0044416 ! induction by symbiont of host defense response + +[Term] +id: GO:0052103 +name: induction by symbiont of host induced systemic resistance +namespace: biological_process +alt_id: GO:0052288 +alt_id: GO:0052532 +alt_id: GO:0052533 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of induced systemic resistance in host" EXACT [] +synonym: "activation by organism of ISR in host" EXACT [] +synonym: "activation by symbiont of induced systemic resistance in host" NARROW [] +synonym: "induction by organism of induced systemic resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by organism of ISR in host" EXACT [] +synonym: "induction by symbiont of induced systemic resistance in host" EXACT [] +synonym: "positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of host induced systemic resistance" RELATED [] +synonym: "positive regulation by symbiont of induced systemic resistance in host" RELATED [] +synonym: "stimulation by symbiont of induced systemic resistance in host" NARROW [] +synonym: "up regulation by symbiont of induced systemic resistance in host" RELATED [] +synonym: "up-regulation by symbiont of induced systemic resistance in host" RELATED [] +synonym: "upregulation by symbiont of induced systemic resistance in host" RELATED [] +is_a: GO:0052159 ! modulation by symbiont of host induced systemic resistance +is_a: GO:0052390 ! induction by symbiont of host innate immune response + +[Term] +id: GO:0052104 +name: induction by symbiont of host systemic acquired resistance +namespace: biological_process +alt_id: GO:0052289 +alt_id: GO:0052535 +alt_id: GO:0052537 +def: "Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of SAR in host" EXACT [] +synonym: "activation by organism of systemic acquired resistance in host" EXACT [] +synonym: "induction by organism of SAR in host" EXACT [] +synonym: "induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by symbiont of systemic acquired resistance in host" EXACT [] +synonym: "positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of host systemic acquired resistance" RELATED [] +synonym: "positive regulation by symbiont of systemic acquired resistance in host" RELATED [] +synonym: "stimulation by symbiont of systemic acquired resistance in host" RELATED [] +synonym: "up regulation by symbiont of systemic acquired resistance in host" RELATED [] +synonym: "up-regulation by symbiont of systemic acquired resistance in host" RELATED [] +synonym: "upregulation by symbiont of systemic acquired resistance in host" RELATED [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052160 ! modulation by symbiont of host systemic acquired resistance +is_a: GO:0052390 ! induction by symbiont of host innate immune response + +[Term] +id: GO:0052105 +name: obsolete induction by symbiont of defense-related host cell wall thickening +namespace: biological_process +alt_id: GO:0052290 +alt_id: GO:0052538 +alt_id: GO:0052539 +def: "OBSOLETE. The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process. +synonym: "activation by organism of defense-related host cell wall thickening" EXACT [] +synonym: "activation by organism of host defensive cell wall thickening" EXACT [] +synonym: "activation by symbiont of defense-related host cell wall thickening" EXACT [] +synonym: "induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by organism of host defensive cell wall thickening" EXACT [] +synonym: "positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of host defensive cell wall thickening" RELATED [] +synonym: "positive regulation by symbiont of defense-related host cell wall thickening" RELATED [] +synonym: "stimulation by symbiont of defense-related host cell wall thickening" RELATED [] +synonym: "up regulation by symbiont of defense-related host cell wall thickening" RELATED [] +synonym: "up-regulation by symbiont of defense-related host cell wall thickening" RELATED [] +synonym: "upregulation by symbiont of defense-related host cell wall thickening" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052106 +name: obsolete quorum sensing involved in interaction with host +namespace: biological_process +def: "OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that this term was not clearly defined and usage was inconsistent. +synonym: "quorum sensing during interaction with host" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0052108 +name: obsolete growth or development of symbiont during interaction with host +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'growth of symbiont during interaction with host ; GO:0044116' and 'development of symbiont during interaction with host ; GO:0044115'. +synonym: "growth or development of organism during interaction with host" EXACT [] +synonym: "growth or development of organism in response to host" EXACT [] +synonym: "growth or development of symbiont during interaction with host" EXACT [] +is_obsolete: true +consider: GO:0044115 +consider: GO:0044117 + +[Term] +id: GO:0052109 +name: obsolete induction by symbiont of defense-related host cell wall callose deposition +namespace: biological_process +alt_id: GO:0052107 +alt_id: GO:0052291 +alt_id: GO:0052292 +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process. +synonym: "activation by symbiont of defense-related host cell wall callose deposition" EXACT [] +synonym: "positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of defense-related host callose deposition" RELATED [] +synonym: "positive regulation by symbiont of defense-related host cell wall callose deposition" RELATED [] +synonym: "stimulation by symbiont of defense-related host cell wall callose deposition" RELATED [] +synonym: "up regulation by symbiont of defense-related host cell wall callose deposition" RELATED [] +synonym: "up-regulation by symbiont of defense-related host cell wall callose deposition" RELATED [] +synonym: "upregulation by symbiont of defense-related host cell wall callose deposition" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052110 +name: occlusion by symbiont of host vascular system +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, http://www.thefreedictionary.com] +is_a: GO:0052111 ! modification by symbiont of host structure +is_a: GO:0052495 ! occlusion by organism of vascular system in other organism involved in symbiotic interaction + +[Term] +id: GO:0052111 +name: modification by symbiont of host structure +namespace: biological_process +def: "The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0044003 ! modulation by symbiont of host process +is_a: GO:0052185 ! modification of structure of other organism involved in symbiotic interaction + +[Term] +id: GO:0052112 +name: occlusion by symbiont of host xylem +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052110 ! occlusion by symbiont of host vascular system +is_a: GO:0052497 ! occlusion by organism of xylem in other organism involved in symbiotic interaction + +[Term] +id: GO:0052113 +name: obsolete adaptation to host osmotic environment +namespace: biological_process +def: "OBSOLETE. The responsive adjustment of an organism to the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was made obsolete because adaptation was not deemed to be a valid biological process. +synonym: "adaptation to host osmotic environment" EXACT [] +synonym: "osmotic tolerance to host environment" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052114 +name: obsolete adaptation to host pH environment +namespace: biological_process +def: "OBSOLETE. The responsive adjustment of an organism to the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was made obsolete because adaptation was not deemed to be a valid biological process. +synonym: "adaptation to host pH environment" EXACT [] +synonym: "pH tolerance to host environment" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052115 +name: obsolete energy taxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "energy taxis in response to host environment" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052116 +name: obsolete chemotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "chemotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052117 +name: obsolete aerotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "aerotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052118 +name: obsolete positive energy taxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive energy taxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052119 +name: obsolete negative energy taxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative energy taxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052120 +name: obsolete positive aerotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive aerotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052121 +name: obsolete positive chemotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive chemotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052122 +name: obsolete negative aerotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative aerotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052123 +name: obsolete negative chemotaxis in host environment +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative chemotaxis in response to host environment" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052124 +name: obsolete energy taxis within host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +is_obsolete: true + +[Term] +id: GO:0052125 +name: obsolete energy taxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +is_obsolete: true + +[Term] +id: GO:0052126 +name: movement in host environment +namespace: biological_process +def: "The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "movement in response to host" EXACT [] +is_a: GO:0051701 ! interaction with host + +[Term] +id: GO:0052127 +name: obsolete movement on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0052128 +name: positive energy taxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates." [GOC:mtg_pamgo_17jul06] +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0052129 +name: negative energy taxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates." [GOC:mtg_pamgo_17jul06] +is_a: GO:0009453 ! energy taxis + +[Term] +id: GO:0052130 +name: negative aerotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen." [GOC:dph, GOC:mtg_pamgo_17jul06] +is_a: GO:0009454 ! aerotaxis +is_a: GO:0050919 ! negative chemotaxis +is_a: GO:0052129 ! negative energy taxis + +[Term] +id: GO:0052131 +name: positive aerotaxis +namespace: biological_process +def: "The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen." [GOC:dph, GOC:mtg_pamgo_17jul06] +is_a: GO:0009454 ! aerotaxis +is_a: GO:0050918 ! positive chemotaxis +is_a: GO:0052128 ! positive energy taxis + +[Term] +id: GO:0052132 +name: obsolete positive aerotaxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052133 +name: obsolete positive aerotaxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive aerotaxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052134 +name: obsolete negative aerotaxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052135 +name: obsolete negative aerotaxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative aerotaxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052136 +name: obsolete negative chemotaxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052137 +name: obsolete aerotaxis in host +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "aerotaxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052138 +name: obsolete aerotaxis on or near host +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052139 +name: obsolete negative chemotaxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative chemotaxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052140 +name: obsolete positive chemotaxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive chemotaxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052141 +name: obsolete positive chemotaxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052142 +name: obsolete chemotaxis within host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052143 +name: obsolete chemotaxis on or near host involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "chemotaxis on or near host during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052144 +name: obsolete negative energy taxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative energy taxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052145 +name: obsolete negative energy taxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052146 +name: obsolete positive energy taxis on or near host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052147 +name: obsolete positive energy taxis in host +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive energy taxis within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052148 +name: modulation by symbiont of host catalytic activity +namespace: biological_process +def: "The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modulation by symbiont of host enzyme activity" EXACT [GOC:tb] +synonym: "modulation of catalytic activity of host by symbiont" EXACT [] +synonym: "regulation by symbiont of host catalytic activity" EXACT [] +synonym: "regulation of catalytic activity of host by symbiont" EXACT [] +synonym: "regulation of host catalytic activity by symbiont" EXACT [] +is_a: GO:0052055 ! modulation by symbiont of host molecular function +is_a: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0052149 +name: modulation by symbiont of host peptidase activity +namespace: biological_process +def: "The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by symbiont of host protease activity" NARROW [GOC:bf] +is_a: GO:0052148 ! modulation by symbiont of host catalytic activity +is_a: GO:0052198 ! modulation of peptidase activity in other organism involved in symbiotic interaction +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0052150 +name: modulation by symbiont of host apoptotic process +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'regulation of apoptosis ; GO:0042981'. +synonym: "modulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "modulation by symbiont of host apoptosis" NARROW [] +is_a: GO:0052040 ! modulation by symbiont of host programmed cell death +is_a: GO:0052433 ! modulation by organism of apoptotic process in other organism involved in symbiotic interaction +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0052151 +name: positive regulation by symbiont of host apoptotic process +namespace: biological_process +alt_id: GO:0033669 +alt_id: GO:0052030 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:mtg_pamgo_17jul06] +comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of apoptosis ; GO:0043065'. +synonym: "activation by organism of host apoptosis" EXACT [] +synonym: "activation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "activation by symbiont of host apoptosis" NARROW [] +synonym: "induction by organism of host apoptotic programmed cell death" EXACT [] +synonym: "induction by symbiont of host apoptosis" EXACT [] +synonym: "positive regulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "positive regulation by symbiont of host apoptosis" NARROW [] +synonym: "stimulation by symbiont of host apoptosis" NARROW [] +synonym: "up regulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "up regulation by symbiont of host apoptosis" EXACT [] +synonym: "up-regulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "up-regulation by symbiont of host apoptosis" EXACT [] +synonym: "upregulation by organism of host apoptotic programmed cell death" EXACT [] +synonym: "upregulation by symbiont of host apoptosis" EXACT [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0052042 ! positive regulation by symbiont of host programmed cell death +is_a: GO:0052150 ! modulation by symbiont of host apoptotic process +intersection_of: GO:0044003 ! modulation by symbiont of host process +intersection_of: positively_regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0052154 +name: modulation by symbiont of host B-cell mediated immune response +namespace: biological_process +alt_id: GO:0052293 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "regulation by organism of host B-cell mediated immune response" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052155 +name: modulation by symbiont of host cell-mediated immune response +namespace: biological_process +alt_id: GO:0052294 +def: "Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of host cell-based immune response" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052156 +name: modulation by symbiont of host T-cell mediated immune response +namespace: biological_process +alt_id: GO:0052295 +def: "Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052155 ! modulation by symbiont of host cell-mediated immune response + +[Term] +id: GO:0052157 +name: obsolete modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response +namespace: biological_process +alt_id: GO:0052296 +def: "OBSOLETE. Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mah] +comment: The reason for obsoletion is that this term has been misused. +synonym: "modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of microbe-associated molecular pattern-induced host innate immunity" EXACT [GOC:pg] +synonym: "modulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18808 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052158 +name: modulation by symbiont of host resistance gene-dependent defense response +namespace: biological_process +alt_id: GO:0052297 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense response in host by specific elicitors" EXACT [] +synonym: "modulation by organism of host gene-for-gene resistance" EXACT [] +synonym: "modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0052159 +name: modulation by symbiont of host induced systemic resistance +namespace: biological_process +alt_id: GO:0052298 +def: "Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of induced systemic resistance in host" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052160 +name: modulation by symbiont of host systemic acquired resistance +namespace: biological_process +alt_id: GO:0052299 +def: "Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of systemic acquired resistance in host" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052161 +name: obsolete modulation by symbiont of defense-related host cell wall thickening +namespace: biological_process +alt_id: GO:0052300 +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process. +synonym: "modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of host defensive cell wall thickening" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052162 +name: modulation by symbiont of defense-related host calcium ion flux +namespace: biological_process +alt_id: GO:0052301 +def: "Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of defense-related host Ca2+ flux" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0052163 +name: symbiont defense to host-produced nitric oxide +namespace: biological_process +alt_id: GO:0052060 +alt_id: GO:0052302 +alt_id: GO:0052376 +alt_id: GO:0052551 +alt_id: GO:0052565 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "defense response to host innate immune response nitric oxide production" NARROW [] +synonym: "evasion or tolerance by organism of host nitric oxide" EXACT [] +synonym: "evasion or tolerance by organism of host NO" EXACT [] +synonym: "evasion or tolerance by organism of host-produced nitric oxide" EXACT [] +synonym: "evasion or tolerance by organism of host-produced NO" EXACT [] +synonym: "evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction" BROAD [] +synonym: "evasion or tolerance by symbiont of host-produced nitric oxide" EXACT [] +synonym: "evasion or tolerance of nitric oxide produced by host in response to organism" EXACT [] +synonym: "evasion or tolerance of NO produced by host in response to organism" EXACT [] +synonym: "modulation by organism of defense-related host NO production" EXACT [] +synonym: "modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of defense-related host nitric oxide production" RELATED [] +synonym: "response to defense-related host nitric oxide production" RELATED [] +synonym: "response to defense-related nitric oxide production by other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0042783 ! evasion of host immune response +is_a: GO:0071500 ! cellular response to nitrosative stress +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18798 xsd:anyURI + +[Term] +id: GO:0052164 +name: symbiont defense to host-produced reactive oxygen species +namespace: biological_process +alt_id: GO:0052059 +alt_id: GO:0052303 +alt_id: GO:0052385 +alt_id: GO:0052550 +alt_id: GO:0052567 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "evasion by symbiont of cellular damage caused by host oxidative burst" NARROW [] +synonym: "evasion or tolerance by organism of host-produced reactive oxygen species" EXACT [] +synonym: "evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction" BROAD [] +synonym: "evasion or tolerance by organism of reactive oxygen species produced during host defense response" EXACT [] +synonym: "evasion or tolerance by symbiont of host-produced reactive oxygen species" EXACT [] +synonym: "evasion or tolerance by symbiont of reactive oxygen species produced by other organism involved in symbiotic interaction" BROAD [] +synonym: "evasion or tolerance of defense-related host metabolic burst" EXACT [] +synonym: "evasion or tolerance of defense-related host oxidative burst" EXACT [] +synonym: "evasion or tolerance of defense-related host respiratory burst" EXACT [] +synonym: "evasion or tolerance of host-produced active oxygen species" EXACT [] +synonym: "evasion or tolerance of host-produced AOS" EXACT [] +synonym: "evasion or tolerance of host-produced reactive oxygen intermediates" EXACT [] +synonym: "evasion or tolerance of host-produced ROIs" EXACT [] +synonym: "evasion or tolerance of host-produced ROS" EXACT [] +synonym: "evasion or tolerance of reactive oxygen species produced by host" EXACT [] +synonym: "modulation by organism of defense-related host active oxygen species production" EXACT [] +synonym: "modulation by organism of defense-related host AOS production" EXACT [] +synonym: "modulation by organism of defense-related host metabolic burst" EXACT [] +synonym: "modulation by organism of defense-related host oxidative burst" EXACT [] +synonym: "modulation by organism of defense-related host reactive oxidative species production" EXACT [] +synonym: "modulation by organism of defense-related host reactive oxygen intermediate production" EXACT [] +synonym: "modulation by organism of defense-related host respiratory burst" EXACT [] +synonym: "modulation by organism of defense-related host ROI production" EXACT [] +synonym: "modulation by organism of defense-related host ROS production" EXACT [] +synonym: "modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of defense-related host reactive oxygen species production" RELATED [] +synonym: "response to defense-related host reactive oxygen species production" RELATED [] +synonym: "response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0042783 ! evasion of host immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18697 xsd:anyURI + +[Term] +id: GO:0052165 +name: symbiont defense to host-produced phytoalexin +namespace: biological_process +alt_id: GO:0052061 +alt_id: GO:0052304 +alt_id: GO:0052378 +alt_id: GO:0052549 +alt_id: GO:0052566 +def: "Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "evasion or tolerance by symbiont of host-produced phytoalexins" EXACT [] +synonym: "evasion or tolerance of phytoalexins" EXACT [] +synonym: "evasion or tolerance of phytoalexins produced by host in response to organism" EXACT [] +synonym: "host phytoalexin detoxification" NARROW [] +synonym: "modulation by organism of phytoalexin production in other organism involved in symbiotic interaction" NARROW [] +synonym: "modulation by symbiont of host phytoalexin production" NARROW [] +synonym: "phytoalexin detoxification" NARROW [] +synonym: "response to host phytoalexin production" BROAD [] +synonym: "response to phytoalexin production by other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0042783 ! evasion of host immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18798 xsd:anyURI + +[Term] +id: GO:0052167 +name: modulation by symbiont of host innate immune response +namespace: biological_process +alt_id: GO:0052306 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of innate immune response in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of host innate immunity" EXACT [GOC:pg] +synonym: "modulation of host innate immune response" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052168 +name: modulation by symbiont of defense-related host calcium-dependent protein kinase pathway +namespace: biological_process +alt_id: GO:0052307 +def: "Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of defense-related host CDPK pathway" EXACT [] +is_a: GO:0052031 ! modulation by symbiont of host defense response + +[Term] +id: GO:0052169 +name: obsolete pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response +namespace: biological_process +def: "OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mah] +comment: This term was obsoleted because it has been misused. +synonym: "pathogen-associated molecular pattern dependent modulation by symbiont of host innate immunity" EXACT [GOC:pg] +is_obsolete: true +consider: GO:0002221 +consider: GO:0002752 +consider: GO:0052034 + +[Term] +id: GO:0052170 +name: suppression by symbiont of host innate immune response +namespace: biological_process +alt_id: GO:0052309 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host innate immunity" EXACT [] +synonym: "down-regulation by symbiont of host innate immunity" EXACT [] +synonym: "downregulation by symbiont of host innate immunity" EXACT [] +synonym: "inhibition by symbiont of host innate immunity" NARROW [] +synonym: "negative regulation by symbiont of host innate immune response" EXACT [] +synonym: "negative regulation by symbiont of host innate immunity" EXACT [GOC:pg] +synonym: "negative regulation of host innate immune response" EXACT [] +synonym: "negative regulation of innate immune response in other organism" BROAD [] +is_a: GO:0044414 ! suppression of host defenses by symbiont +is_a: GO:0052167 ! modulation by symbiont of host innate immune response +is_a: GO:0052562 ! suppression by symbiont of host immune response + +[Term] +id: GO:0052171 +name: obsolete growth or development during symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development during symbiotic interaction ; GO:0044111' and 'growth during symbiotic interaction ; GO:0044110'. +synonym: "growth or development during symbiotic interaction" EXACT [] +is_obsolete: true +consider: GO:0044110 +consider: GO:0044111 + +[Term] +id: GO:0052172 +name: metabolism by symbiont of host cell wall cellulose +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052409 ! metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction + +[Term] +id: GO:0052173 +name: response to defenses of other organism +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism." [GOC:mtg_pamgo_17jul06] +synonym: "response to defenses of other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "response to defenses of other organism involved in symbiotic interaction" RELATED [] +is_a: GO:0051707 ! response to other organism +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17930 xsd:anyURI + +[Term] +id: GO:0052174 +name: metabolism by symbiont of host macromolecule +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052002 ! metabolism by symbiont of substance in host +is_a: GO:0052229 ! metabolism of macromolecule in other organism involved in symbiotic interaction + +[Term] +id: GO:0052175 +name: metabolism by symbiont of host carbohydrate +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052174 ! metabolism by symbiont of host macromolecule +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052176 +name: metabolism by symbiont of host glucan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052415 ! metabolism by organism of glucan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052177 +name: metabolism by symbiont of host xylan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052421 ! metabolism by organism of xylan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052178 +name: metabolism by symbiont of host cell wall chitin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052411 ! metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction + +[Term] +id: GO:0052179 +name: metabolism by symbiont of host cell wall pectin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052175 ! metabolism by symbiont of host carbohydrate +is_a: GO:0052413 ! metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction + +[Term] +id: GO:0052180 +name: negative regulation of peptidase activity in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation of protease activity in other organism during symbiotic interaction" EXACT [] +synonym: "down-regulation of protease activity in other organism during symbiotic interaction" EXACT [] +synonym: "downregulation of protease activity in other organism during symbiotic interaction" EXACT [] +synonym: "inhibition of protease activity in other organism during symbiotic interaction" NARROW [] +synonym: "negative regulation of protease activity in other organism during symbiotic interaction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0035940 ! negative regulation of peptidase activity in other organism +is_a: GO:0052198 ! modulation of peptidase activity in other organism involved in symbiotic interaction +is_a: GO:0052199 ! negative regulation of catalytic activity in other organism involved in symbiotic interaction + +[Term] +id: GO:0052181 +name: obsolete modulation by host of symbiont defense response +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response. +is_obsolete: true + +[Term] +id: GO:0052182 +name: obsolete modification by host of symbiont morphology or physiology via secreted substance +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true + +[Term] +id: GO:0052183 +name: modification by host of symbiont structure +namespace: biological_process +def: "The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052185 ! modification of structure of other organism involved in symbiotic interaction + +[Term] +id: GO:0052184 +name: obsolete modulation by organism of symbiont hormone or growth regulator levels +namespace: biological_process +def: "OBSOLETE. The alteration by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont hormone or growth regulator levels" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052185 +name: modification of structure of other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification of structure of other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0052187 +name: modification by host of symbiont cellular component +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052183 ! modification by host of symbiont structure +is_a: GO:0052188 ! modification of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052188 +name: modification of cellular component in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification of cellular component in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052185 ! modification of structure of other organism involved in symbiotic interaction + +[Term] +id: GO:0052189 +name: obsolete modulation by symbiont of defense-related host cell wall callose deposition +namespace: biological_process +alt_id: GO:0052090 +alt_id: GO:0052285 +alt_id: GO:0052310 +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process. +synonym: "modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction" BROAD [] +synonym: "modulation by symbiont of defense-related host callose deposition" BROAD [] +is_obsolete: true + +[Term] +id: GO:0052190 +name: obsolete modulation by symbiont of host phagocytosis +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052191 +name: obsolete positive regulation by symbiont of host phagocytosis +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "activation by symbiont of host phagocytosis" NARROW [] +synonym: "stimulation by symbiont of host phagocytosis" NARROW [] +synonym: "up regulation by symbiont of host phagocytosis" EXACT [] +synonym: "up-regulation by symbiont of host phagocytosis" EXACT [] +synonym: "upregulation by symbiont of host phagocytosis" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052192 +name: obsolete movement in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "locomotion in environment of other organism during symbiotic interaction" RELATED [] +synonym: "movement in environment of other organism during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052193 +name: obsolete movement in symbiont environment +namespace: biological_process +def: "OBSOLETE. The directed movement of an organism or motile cell on, within or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_obsolete: true + +[Term] +id: GO:0052194 +name: obsolete movement on or near symbiont +namespace: biological_process +def: "OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_obsolete: true + +[Term] +id: GO:0052195 +name: obsolete movement on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "movement on or near other organism during symbiotic interaction" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0052196 +name: obsolete negative regulation by host of symbiont defense response +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was made obsolete because it is not relevant for the host in a host-symbiont interaction. +synonym: "down regulation by host of symbiont defense response" EXACT [] +synonym: "down-regulation by host of symbiont defense response" EXACT [] +synonym: "downregulation by host of symbiont defense response" EXACT [] +synonym: "inhibition by host of symbiont defense response" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14862 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052197 +name: obsolete positive regulation by host of symbiont defense response +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response. +synonym: "activation by host of symbiont defense response" NARROW [] +synonym: "stimulation by host of symbiont defense response" NARROW [] +synonym: "up regulation by host of symbiont defense response" EXACT [] +synonym: "up-regulation by host of symbiont defense response" EXACT [] +synonym: "upregulation by host of symbiont defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052198 +name: modulation of peptidase activity in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of protease activity in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "modulation of protease activity in other organism involved in symbiotic interaction" NARROW [GOC:bf] +is_a: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction + +[Term] +id: GO:0052199 +name: negative regulation of catalytic activity in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +synonym: "down-regulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +synonym: "downregulation of enzyme activity in other organism during symbiotic interaction" RELATED [] +synonym: "inhibition of enzyme activity in other organism" EXACT [] +synonym: "inhibition of enzyme activity in other organism during symbiotic interaction" NARROW [] +synonym: "negative regulation of enzyme activity in other organism during symbiotic interaction" EXACT [GOC:tb] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction +is_a: GO:0052204 ! negative regulation of molecular function in other organism involved in symbiotic interaction +intersection_of: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction +intersection_of: negatively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0052200 +name: response to host defenses +namespace: biological_process +alt_id: GO:0075140 +alt_id: GO:0075145 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "maintenance of symbiont tolerance to host defense molecules" NARROW [] +synonym: "response of symbiont to host defense molecules" NARROW [] +synonym: "response to host defense molecules" NARROW [] +is_a: GO:0052173 ! response to defenses of other organism +is_a: GO:0075136 ! response to host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18827 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18951 xsd:anyURI + +[Term] +id: GO:0052201 +name: response to symbiont defenses +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0009608 ! response to symbiont +is_a: GO:0052173 ! response to defenses of other organism + +[Term] +id: GO:0052202 +name: obsolete negative regulation by symbiont of defense-related host cell wall callose deposition +namespace: biological_process +alt_id: GO:0052087 +alt_id: GO:0052282 +alt_id: GO:0052311 +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process. +synonym: "down regulation by symbiont of defense-related host cell wall callose deposition" EXACT [] +synonym: "down-regulation by symbiont of defense-related host cell wall callose deposition" EXACT [] +synonym: "downregulation by symbiont of defense-related host cell wall callose deposition" EXACT [] +synonym: "inhibition by symbiont of defense-related host cell wall callose deposition" NARROW [] +synonym: "negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of defense-related host callose deposition" BROAD [] +is_obsolete: true + +[Term] +id: GO:0052203 +name: modulation of catalytic activity in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modulation of enzyme activity within other organism during symbiotic interaction" EXACT [GOC:tb] +is_a: GO:0050790 ! regulation of catalytic activity +is_a: GO:0052205 ! modulation of molecular function in other organism involved in symbiotic interaction + +[Term] +id: GO:0052204 +name: negative regulation of molecular function in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation of protein function in other organism during symbiotic interaction" EXACT [] +synonym: "down-regulation of protein function in other organism during symbiotic interaction" EXACT [] +synonym: "downregulation of protein function in other organism during symbiotic interaction" EXACT [] +synonym: "inhibition of protein function in other organism" EXACT [] +synonym: "inhibition of protein function in other organism during symbiotic interaction" NARROW [] +synonym: "negative regulation of protein function in other organism during symbiotic interaction" EXACT [GOC:dph, GOC:tb] +is_a: GO:0044362 ! negative regulation of molecular function in other organism +is_a: GO:0052205 ! modulation of molecular function in other organism involved in symbiotic interaction + +[Term] +id: GO:0052205 +name: modulation of molecular function in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modification of molecular function in other organism during symbiotic interaction" EXACT [] +synonym: "modification of protein function in other organism during symbiotic interaction" EXACT [GOC:dph, GOC:tb] +synonym: "modulation of molecular function in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044359 ! modulation of molecular function in other organism +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0052206 +name: obsolete modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification of morphology or physiology of other organism via protein secreted by type II secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052207 +name: obsolete modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification of morphology or physiology of other organism via protein secreted by type III secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052208 +name: obsolete modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification of morphology or physiology of other organism via substance secreted by type IV secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052209 +name: obsolete interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with other organism via substance secreted by type IV secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052210 +name: obsolete interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with other organism via protein secreted by type III secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052211 +name: obsolete interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with other organism via protein secreted by type II secretion system during symbiotic interaction" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0052212 +name: obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification of host morphology or physiology via effector molecule" NARROW [] +synonym: "modification of host morphology or physiology via ellicitor" NARROW [] +synonym: "modification of morphology or physiology of other organism via secreted substance during symbiotic interaction" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0052213 +name: obsolete interaction with symbiont via secreted substance +namespace: biological_process +def: "OBSOLETE. An interaction with a symbiont organism mediated by a substance secreted by a host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that this process was not clearly defined, and propably represented some immune response. . +synonym: "interaction with symbiont via secreted substance during symbiotic interaction" RELATED [GOC:dph] +synonym: "interaction with symbiont via secreted substance involved in symbiotic interaction" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052214 +name: metabolism of substance in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism of substance in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044033 ! multi-organism metabolic process +is_a: GO:0044419 ! interspecies interaction between organisms + +[Term] +id: GO:0052215 +name: obsolete energy taxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "energy taxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "energy taxis in response to environment of other organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052216 +name: obsolete chemotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "chemotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "chemotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052217 +name: obsolete aerotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "aerotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "aerotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052218 +name: obsolete positive energy taxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive energy taxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive energy taxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052219 +name: obsolete negative energy taxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative energy taxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative energy taxis in response to environment of other organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052220 +name: obsolete positive aerotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive aerotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive aerotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052221 +name: obsolete positive chemotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive chemotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive chemotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052222 +name: obsolete negative aerotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative aerotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative aerotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052223 +name: obsolete negative chemotaxis in environment of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative chemotaxis in environment of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative chemotaxis in response to environment of other organism" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052224 +name: obsolete energy taxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "energy taxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "energy taxis within other organism during symbiotic interaction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052225 +name: obsolete energy taxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "energy taxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0052226 +name: obsolete biosynthesis of substance in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "biosynthesis of substance in other organism during symbiotic interaction" RELATED [GOC:dph] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18787 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052227 +name: catabolism of substance in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "catabolism of substance in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044035 ! multi-organism catabolic process +is_a: GO:0052214 ! metabolism of substance in other organism involved in symbiotic interaction + +[Term] +id: GO:0052228 +name: metabolism by symbiont of host protein +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052174 ! metabolism by symbiont of host macromolecule +is_a: GO:0052418 ! metabolism by organism of protein in other organism involved in symbiotic interaction + +[Term] +id: GO:0052229 +name: metabolism of macromolecule in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism of macromolecule in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0052214 ! metabolism of substance in other organism involved in symbiotic interaction + +[Term] +id: GO:0052230 +name: modulation of intracellular transport in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of intracellular trafficking in other organism" EXACT [] +synonym: "modulation of intracellular transport in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0052231 +name: obsolete modulation of phagocytosis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "modulation of phagocytosis in other organism during symbiotic interaction" RELATED [GOC:dph] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052232 +name: obsolete positive aerotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive aerotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052233 +name: obsolete positive aerotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive aerotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive aerotaxis within other organism during symbiotic interaction" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052234 +name: obsolete negative aerotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative aerotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052235 +name: obsolete negative aerotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative aerotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative aerotaxis within other organism during symbiotic interaction" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052236 +name: obsolete negative chemotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative chemotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052237 +name: obsolete aerotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "aerotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "aerotaxis within other organism during symbiotic interaction" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052238 +name: obsolete aerotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "aerotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052239 +name: obsolete negative chemotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative chemotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative chemotaxis within other organism during symbiotic interaction" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052240 +name: obsolete positive chemotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive chemotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive chemotaxis within other organism during symbiotic interaction" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052241 +name: obsolete positive chemotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive chemotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052242 +name: obsolete chemotaxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "chemotaxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "chemotaxis within other organism during symbiotic interaction" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052243 +name: obsolete chemotaxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "chemotaxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052244 +name: obsolete negative energy taxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative energy taxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative energy taxis within other organism during symbiotic interaction" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052245 +name: obsolete negative energy taxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "negative energy taxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052246 +name: obsolete positive energy taxis on or near other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive energy taxis on or near other organism during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052247 +name: obsolete positive energy taxis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because it represents both a process and a location. +synonym: "positive energy taxis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive energy taxis within other organism during symbiotic interaction" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18819 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052248 +name: modulation of programmed cell death in other organism involved in symbiotic interaction +namespace: biological_process +alt_id: GO:0052459 +def: "Any process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "modulation of programmed cell death in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044531 ! modulation of programmed cell death in other organism +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0052249 +name: modulation of RNA levels in other organism involved in symbiotic interaction +namespace: biological_process +def: "The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of RNA levels in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction + +[Term] +id: GO:0052257 +name: obsolete pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mah] +comment: This term was obsoleted because it has been misused. +synonym: "general elicitor dependent induction of innate immunity of other organism" EXACT [] +synonym: "general elicitor-dependent induction of innate immunity of other organism" EXACT [] +synonym: "MAMP dependent induction of innate immunity of other organism" EXACT [] +synonym: "MAMP-dependent induction of innate immunity of other organism" EXACT [] +synonym: "PAMP dependent induction of innate immunity of other organism" EXACT [] +synonym: "PAMP-dependent induction of innate immunity of other organism" EXACT [] +synonym: "pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism involved in symbiotic interaction" EXACT [GOC:pg] +is_obsolete: true +consider: GO:0002221 +consider: GO:0002752 +consider: GO:0052034 + +[Term] +id: GO:0052308 +name: obsolete pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mah] +comment: This term was obsoleted because it has been misused. +synonym: "pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism involved in symbiotic interaction" EXACT [GOC:pg] +is_obsolete: true +consider: GO:0002221 +consider: GO:0002752 +consider: GO:0052034 + +[Term] +id: GO:0052312 +name: modulation of transcription in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of transcription in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction +is_a: GO:2001141 ! regulation of RNA biosynthetic process + +[Term] +id: GO:0052313 +name: modulation of nutrient release from other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation of nutrient release from other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0051817 ! modulation of process of other organism involved in symbiotic interaction +relationship: part_of GO:0051816 ! acquisition of nutrients from other organism during symbiotic interaction + +[Term] +id: GO:0052314 +name: phytoalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response." [Wikipedia:Phytoalexin] +subset: goslim_pir +synonym: "phytoalexin metabolism" EXACT [] +is_a: GO:0009404 ! toxin metabolic process + +[Term] +id: GO:0052315 +name: phytoalexin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response." [Wikipedia:Phytoalexin] +synonym: "phytoalexin biosynthesis" EXACT [] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0052316 +name: phytoalexin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response." [GOC:ai] +synonym: "phytoalexin catabolism" EXACT [] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0052317 +name: camalexin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving camalexin, an indole phytoalexin." [GOC:ai] +synonym: "camalexin metabolism" EXACT [] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0046217 ! indole phytoalexin metabolic process + +[Term] +id: GO:0052318 +name: regulation of phytoalexin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response." [GOC:ai] +synonym: "regulation of phytoalexin metabolism" EXACT [] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052314 ! phytoalexin metabolic process +relationship: regulates GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0052319 +name: regulation of phytoalexin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:ai] +synonym: "regulation of phytoalexin biosynthesis" EXACT [] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0052318 ! regulation of phytoalexin metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052315 ! phytoalexin biosynthetic process +relationship: regulates GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0052320 +name: positive regulation of phytoalexin metabolic process +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins." [GOC:mtg_pamgo_17jul06] +synonym: "activation of phytoalexin metabolism" NARROW [] +synonym: "positive regulation of phytoalexin metabolism" RELATED [] +synonym: "stimulation of phytoalexin metabolism" NARROW [] +synonym: "up regulation of phytoalexin metabolism" EXACT [] +synonym: "up-regulation of phytoalexin metabolism" EXACT [] +synonym: "upregulation of phytoalexin metabolism" EXACT [] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0052318 ! regulation of phytoalexin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052314 ! phytoalexin metabolic process +relationship: positively_regulates GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0052321 +name: negative regulation of phytoalexin metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins." [GOC:ai] +synonym: "down regulation of phytoalexin metabolism" EXACT [] +synonym: "down-regulation of phytoalexin metabolism" EXACT [] +synonym: "downregulation of phytoalexin metabolism" EXACT [] +synonym: "inhibition of phytoalexin metabolism" NARROW [] +synonym: "negative regulation of phytoalexin metabolism" EXACT [] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0052318 ! regulation of phytoalexin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052314 ! phytoalexin metabolic process +relationship: negatively_regulates GO:0052314 ! phytoalexin metabolic process + +[Term] +id: GO:0052322 +name: positive regulation of phytoalexin biosynthetic process +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:mtg_pamgo_17jul06] +synonym: "activation of phytoalexin biosynthesis" NARROW [] +synonym: "positive regulation of phytoalexin biosynthesis" EXACT [] +synonym: "stimulation of phytoalexin biosynthesis" NARROW [] +synonym: "up regulation of phytoalexin biosynthesis" EXACT [] +synonym: "up-regulation of phytoalexin biosynthesis" EXACT [] +synonym: "upregulation of phytoalexin biosynthesis" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0052319 ! regulation of phytoalexin biosynthetic process +is_a: GO:0052320 ! positive regulation of phytoalexin metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052315 ! phytoalexin biosynthetic process +relationship: positively_regulates GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0052323 +name: negative regulation of phytoalexin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:ai] +synonym: "down regulation of phytoalexin biosynthesis" EXACT [] +synonym: "down-regulation of phytoalexin biosynthesis" EXACT [] +synonym: "downregulation of phytoalexin biosynthesis" EXACT [] +synonym: "inhibition of phytoalexin biosynthesis" NARROW [] +synonym: "negative regulation of phytoalexin biosynthesis" EXACT [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0052319 ! regulation of phytoalexin biosynthetic process +is_a: GO:0052321 ! negative regulation of phytoalexin metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052315 ! phytoalexin biosynthetic process +relationship: negatively_regulates GO:0052315 ! phytoalexin biosynthetic process + +[Term] +id: GO:0052324 +name: plant-type cell wall cellulose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall." [GOC:ai] +synonym: "cell wall cellulose biosynthesis" EXACT [] +synonym: "cellulose biosynthesis during cell wall biosynthesis" RELATED [] +is_a: GO:0030244 ! cellulose biosynthetic process +is_a: GO:0034410 ! cell wall beta-glucan biosynthetic process +is_a: GO:0052541 ! plant-type cell wall cellulose metabolic process +relationship: part_of GO:0009832 ! plant-type cell wall biogenesis + +[Term] +id: GO:0052325 +name: cell wall pectin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall." [GOC:ai] +synonym: "cell wall pectin biosynthesis" EXACT [] +synonym: "pectin biosynthesis during cell wall organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045489 ! pectin biosynthetic process +is_a: GO:0052546 ! cell wall pectin metabolic process +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process +relationship: part_of GO:0009832 ! plant-type cell wall biogenesis + +[Term] +id: GO:0052326 +name: obsolete interaction with symbiont via protein secreted by type IV secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type IV secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "interaction with symbiont via protein secreted by type IV secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052327 +name: obsolete interaction with symbiont via protein secreted by type II secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type II secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "interaction with symbiont via protein secreted by type II secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052328 +name: obsolete interaction with symbiont via protein secreted by type III secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type III secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "interaction with symbiont via protein secreted by type III secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052330 +name: positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction +namespace: biological_process +alt_id: GO:0052518 +alt_id: GO:0052529 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:jl, GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "enhancement of other organism programmed cell death by organism" RELATED [] +synonym: "positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "positive regulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "stimulation by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "upregulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "upregulation by organism of programmed cell death in other organism involved in symbiotic interaction" EXACT [] +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0051712 ! positive regulation of killing of cells of other organism +is_a: GO:0052248 ! modulation of programmed cell death in other organism involved in symbiotic interaction +relationship: positively_regulates GO:0051883 ! killing of cells in other organism involved in symbiotic interaction + +[Term] +id: GO:0052331 +name: hemolysis in other organism involved in symbiotic interaction +namespace: biological_process +def: "The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction." [GOC:add, UniProtKB-KW:KW-0354] +synonym: "haemolysis in other organism involved in symbiotic interaction" EXACT [] +synonym: "hemolysin activity" RELATED [] +synonym: "hemolysis by organism of erythrocytes in other organism during symbiotic interaction" RELATED [] +synonym: "hemolysis by organism of RBCs in other organism during symbiotic interaction" RELATED [CL:0000232] +synonym: "hemolysis by organism of red blood cells in other organism during symbiotic interaction" RELATED [CL:0000232] +synonym: "hemolysis of cells in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "hemolysis of cells in other organism involved in symbiotic interaction" EXACT [GOC:bf] +is_a: GO:0044179 ! hemolysis in other organism +is_a: GO:0051801 ! cytolysis in other organism involved in symbiotic interaction +intersection_of: GO:0044179 ! hemolysis in other organism +intersection_of: part_of GO:0044403 ! symbiotic process +relationship: part_of GO:0044403 ! symbiotic process + +[Term] +id: GO:0052332 +name: modification by organism of membrane in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification by organism of cell membrane in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "modification by organism of cell membrane in other organism involved in symbiotic interaction" NARROW [GOC:bf, GOC:jl] +is_a: GO:0052188 ! modification of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052333 +name: modification by organism of cell wall of other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of cell wall of other organism" RELATED [] +synonym: "modification by organism of cell wall of other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052188 ! modification of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052334 +name: modification by organism of cytoskeleton of other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification by organism of cytoskeleton of other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052188 ! modification of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052335 +name: modification by host of symbiont cytoskeleton +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052187 ! modification by host of symbiont cellular component +is_a: GO:0052334 ! modification by organism of cytoskeleton of other organism involved in symbiotic interaction + +[Term] +id: GO:0052336 +name: modification by host of symbiont cell wall +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "metabolism of symbiont cell wall by organism" EXACT [] +is_a: GO:0052187 ! modification by host of symbiont cellular component +is_a: GO:0052333 ! modification by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052337 +name: modification by host of symbiont membrane +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modification by host of symbiont cell membrane" NARROW [GOC:bf, GOC:jl] +is_a: GO:0052187 ! modification by host of symbiont cellular component +is_a: GO:0052332 ! modification by organism of membrane in other organism involved in symbiotic interaction + +[Term] +id: GO:0052338 +name: disruption by host of symbiont cell wall +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism of symbiont cell wall by organism" EXACT [] +synonym: "degradation of symbiont cell wall by organism" EXACT [] +synonym: "disassembly by host of symbiont cell wall" EXACT [] +is_a: GO:0052336 ! modification by host of symbiont cell wall +is_a: GO:0052339 ! disruption by organism of cell wall of other organism involved in symbiotic interaction +is_a: GO:0052367 ! disruption by host of symbiont cellular component + +[Term] +id: GO:0052339 +name: disruption by organism of cell wall of other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "disassembly by organism of cell wall of other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052333 ! modification by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052340 +name: catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of cell wall cellulose in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0030245 ! cellulose catabolic process +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052409 ! metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction +relationship: part_of GO:0044278 ! cell wall disruption in other organism +relationship: part_of GO:0052339 ! disruption by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052341 +name: catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of cell wall pectin in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052413 ! metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction +relationship: part_of GO:0044278 ! cell wall disruption in other organism +relationship: part_of GO:0052339 ! disruption by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052342 +name: catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of cell wall chitin in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0006039 ! cell wall chitin catabolic process +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052411 ! metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction +relationship: part_of GO:0052339 ! disruption by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0052343 +name: obsolete positive regulation by organism of symbiont phytoalexin production +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont phytoalexin production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052344 +name: positive regulation by symbiont of host phytoalexin production +namespace: biological_process +alt_id: GO:0052329 +def: "Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host phytoalexin production" NARROW [] +synonym: "positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction" BROAD [] +synonym: "stimulation by symbiont of host phytoalexin production" NARROW [] +synonym: "up regulation by symbiont of host phytoalexin production" EXACT [] +synonym: "up-regulation by symbiont of host phytoalexin production" EXACT [] +synonym: "upregulation by symbiont of host phytoalexin production" EXACT [] +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052346 +name: obsolete positive regulation by organism of defense-related symbiont nitric oxide production +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense-related symbiont nitric oxide production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont NO production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052349 +name: obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense-related symbiont active oxygen species production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont AOS production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont metabolic burst" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont oxidative burst" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont reactive oxidative species production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont reactive oxygen intermediate production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont reactive oxygen species production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont respiratory burst" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont ROI production" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont ROS production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052350 +name: obsolete induction by organism of induced systemic resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates induced systemic resistance in the symbiont; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of induced systemic resistance in symbiont" EXACT [] +synonym: "activation by organism of ISR in symbiont" EXACT [] +synonym: "induction by organism of induced systemic resistance in symbiont" EXACT [] +synonym: "induction by organism of ISR in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052351 +name: obsolete induction by organism of systemic acquired resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of SAR in symbiont" EXACT [] +synonym: "activation by organism of systemic acquired resistance in symbiont" EXACT [] +synonym: "induction by organism of SAR in symbiont" EXACT [] +synonym: "induction by organism of systemic acquired resistance in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052352 +name: obsolete biosynthesis by host of substance in symbiont +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +comment: This term was obsoleted because there is no evidence that this process exists. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18787 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052353 +name: catabolism by host of symbiont carbohydrate +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052360 ! catabolism by host of symbiont macromolecule +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate + +[Term] +id: GO:0052354 +name: catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of carbohydrate in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044041 ! multi-organism carbohydrate catabolic process +is_a: GO:0052361 ! catabolism by organism of macromolecule in other organism involved in symbiotic interaction +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052355 +name: catabolism by host of symbiont cell wall cellulose +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052340 ! catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction +is_a: GO:0052353 ! catabolism by host of symbiont carbohydrate +is_a: GO:0052408 ! metabolism by host of symbiont cell wall cellulose +relationship: part_of GO:0052338 ! disruption by host of symbiont cell wall + +[Term] +id: GO:0052356 +name: catabolism by host of symbiont cell wall chitin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052342 ! catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction +is_a: GO:0052353 ! catabolism by host of symbiont carbohydrate +is_a: GO:0052410 ! metabolism by host of symbiont cell wall chitin +relationship: part_of GO:0052338 ! disruption by host of symbiont cell wall + +[Term] +id: GO:0052357 +name: catabolism by host of symbiont cell wall pectin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052341 ! catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction +is_a: GO:0052353 ! catabolism by host of symbiont carbohydrate +is_a: GO:0052412 ! metabolism by host of symbiont cell wall pectin +relationship: part_of GO:0052338 ! disruption by host of symbiont cell wall + +[Term] +id: GO:0052358 +name: catabolism by host of symbiont glucan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052353 ! catabolism by host of symbiont carbohydrate +is_a: GO:0052359 ! catabolism by organism of glucan in other organism involved in symbiotic interaction +is_a: GO:0052414 ! metabolism by host of symbiont glucan + +[Term] +id: GO:0052359 +name: catabolism by organism of glucan in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of glucan in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052415 ! metabolism by organism of glucan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052360 +name: catabolism by host of symbiont macromolecule +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052361 ! catabolism by organism of macromolecule in other organism involved in symbiotic interaction +is_a: GO:0052364 ! catabolism by host of substance in symbiont +is_a: GO:0052416 ! metabolism by host of symbiont macromolecule + +[Term] +id: GO:0052361 +name: catabolism by organism of macromolecule in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of macromolecule in other organism during symbiotic interaction" RELATED [goc:dph] +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0052227 ! catabolism of substance in other organism involved in symbiotic interaction +is_a: GO:0052229 ! metabolism of macromolecule in other organism involved in symbiotic interaction + +[Term] +id: GO:0052362 +name: catabolism by host of symbiont protein +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052360 ! catabolism by host of symbiont macromolecule +is_a: GO:0052363 ! catabolism by organism of protein in other organism involved in symbiotic interaction +is_a: GO:0052417 ! metabolism by host of symbiont protein + +[Term] +id: GO:0052363 +name: catabolism by organism of protein in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of protein in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0030163 ! protein catabolic process +is_a: GO:0052361 ! catabolism by organism of macromolecule in other organism involved in symbiotic interaction +is_a: GO:0052418 ! metabolism by organism of protein in other organism involved in symbiotic interaction + +[Term] +id: GO:0052364 +name: catabolism by host of substance in symbiont +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052227 ! catabolism of substance in other organism involved in symbiotic interaction +is_a: GO:0052419 ! metabolism by host of substance in symbiont + +[Term] +id: GO:0052365 +name: catabolism by host of symbiont xylan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052353 ! catabolism by host of symbiont carbohydrate +is_a: GO:0052366 ! catabolism by organism of xylan in other organism involved in symbiotic interaction +is_a: GO:0052420 ! metabolism by host of symbiont xylan + +[Term] +id: GO:0052366 +name: catabolism by organism of xylan in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism by organism of xylan in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0045493 ! xylan catabolic process +is_a: GO:0052354 ! catabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052421 ! metabolism by organism of xylan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052367 +name: disruption by host of symbiont cellular component +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism of symbiont cellular component by organism" EXACT [] +synonym: "catabolism of symbiont structural constituent by organism" EXACT [] +synonym: "degradation of symbiont cellular component by organism" EXACT [] +synonym: "disassembly by host of symbiont cellular component" RELATED [] +is_a: GO:0052187 ! modification by host of symbiont cellular component +is_a: GO:0052368 ! disruption by organism of cellular component in other organism involved in symbiotic interaction + +[Term] +id: GO:0052368 +name: disruption by organism of cellular component in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction." [ISBN:0198547684] +synonym: "catabolism of cellular component in other organism" EXACT [] +synonym: "catabolism of structural constituent in other organism" EXACT [] +synonym: "degradation of cellular component in other organism" EXACT [] +synonym: "disassembly by organism of cellular component in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "disassembly by organism of cellular component in other organism involved in symbiotic interaction" RELATED [] +is_a: GO:0052185 ! modification of structure of other organism involved in symbiotic interaction + +[Term] +id: GO:0052372 +name: modulation by symbiont of entry into host +namespace: biological_process +alt_id: GO:0052371 +def: "Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "modulation by symbiont of entry into host" RELATED [] +synonym: "regulation by organism of entry into other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "regulation by organism of entry into other organism involved in symbiotic interaction" RELATED [] +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0044409 ! entry into host +relationship: regulates GO:0044409 ! entry into host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19027 xsd:anyURI + +[Term] +id: GO:0052373 +name: suppression of symbiont entry into host by host +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "down-regulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "downregulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "inhibition by organism of entry into other organism during symbiotic interaction" NARROW [] +synonym: "negative regulation by organism of entry into other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "negative regulation by organism of entry into other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0052374 +name: obsolete negative regulation by symbiont of entry into host +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "down regulation by symbiont of entry into host" EXACT [] +synonym: "down-regulation by symbiont of entry into host" EXACT [] +synonym: "downregulation by symbiont of entry into host" EXACT [] +synonym: "inhibition by symbiont of entry into host" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18779 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052375 +name: obsolete evasion or tolerance by organism of symbiont-produced nitric oxide +namespace: biological_process +def: "OBSOLETE. The process by which an organism avoids the effects of nitric oxide produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "evasion or tolerance by organism of symbiont nitric oxide" EXACT [] +synonym: "evasion or tolerance by organism of symbiont NO" EXACT [] +synonym: "evasion or tolerance by organism of symbiont-produced nitric oxide" EXACT [] +synonym: "evasion or tolerance by organism of symbiont-produced NO" EXACT [] +synonym: "evasion or tolerance of nitric oxide produced by symbiont in response to organism" EXACT [] +synonym: "evasion or tolerance of NO produced by symbiont in response to organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052377 +name: obsolete evasion or tolerance by organism of symbiont-produced phytoalexins +namespace: biological_process +def: "OBSOLETE. The process by which an organism avoids the effects of phytoalexins produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "evasion or tolerance by organism of symbiont phytoalexins" EXACT [] +synonym: "evasion or tolerance by organism of symbiont-produced phytoalexins" EXACT [] +synonym: "evasion or tolerance of phytoalexins produced by symbiont in response to organism" EXACT [] +synonym: "symbiont phytoalexin detoxification" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052379 +name: obsolete modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "modulation by organism of entry into other organism via other organism phagocytosis during symbiotic interaction" RELATED [] +synonym: "modulation by organism of entry into other organism via phagocytosis during symbiotic interaction" RELATED [GOC:tb] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052381 +name: tRNA dimethylallyltransferase activity +namespace: molecular_function +alt_id: GO:0004811 +def: "Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine." [EC:2.5.1.75] +comment: Note that this activity was formerly know in GO and EC as 'tRNA isopentenyltransferase' (EC:2.5.1.8, GO:0004811), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. +synonym: "dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity" EXACT systematic_synonym [EC:2.5.1.75] +synonym: "tRNA isopentenyltransferase activity" RELATED [GOC:mah, GOC:vw] +synonym: "tRNA prenyltransferase activity" BROAD [EC:2.5.1.75] +xref: EC:2.5.1.75 +xref: MetaCyc:RXN0-6274 +xref: Reactome:R-HSA-6784462 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs" +xref: Reactome:R-HSA-6787567 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +creation_date: 2010-07-23T03:07:33Z + +[Term] +id: GO:0052383 +name: obsolete induction by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont innate immune response" EXACT [] +synonym: "activation by organism of symbiont innate immunity" EXACT [] +synonym: "induction by organism of symbiont innate immune response" EXACT [] +synonym: "induction by organism of symbiont innate immunity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052384 +name: obsolete evasion or tolerance by organism of symbiont-produced reactive oxygen species +namespace: biological_process +def: "OBSOLETE. The process by which an organism avoids the effects of reactive oxygen species produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "evasion by organism of cellular damage caused by symbiont oxidative burst" NARROW [] +synonym: "evasion or tolerance by organism of reactive oxygen species produced during symbiont defense response" EXACT [] +synonym: "evasion or tolerance by organism of symbiont-produced reactive oxygen species" EXACT [] +synonym: "evasion or tolerance of defense-related symbiont metabolic burst" EXACT [] +synonym: "evasion or tolerance of defense-related symbiont oxidative burst" EXACT [] +synonym: "evasion or tolerance of defense-related symbiont respiratory burst" EXACT [] +synonym: "evasion or tolerance of reactive oxygen species produced by symbiont in response to organism" EXACT [] +synonym: "evasion or tolerance of symbiont-produced active oxygen species" EXACT [] +synonym: "evasion or tolerance of symbiont-produced AOS" EXACT [] +synonym: "evasion or tolerance of symbiont-produced reactive oxygen intermediates" EXACT [] +synonym: "evasion or tolerance of symbiont-produced ROIs" EXACT [] +synonym: "evasion or tolerance of symbiont-produced ROS" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052386 +name: cell wall thickening +namespace: biological_process +def: "A type of cell wall modification in which the cell wall is reinforced and made thicker." [GOC:mtg_pamgo_17jul06] +is_a: GO:0042545 ! cell wall modification + +[Term] +id: GO:0052387 +name: obsolete induction by organism of symbiont apoptosis +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont apoptosis" EXACT [] +synonym: "activation by organism of symbiont apoptotic programmed cell death" EXACT [] +synonym: "induction by organism of symbiont apoptosis" EXACT [] +synonym: "induction by organism of symbiont apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052390 +name: induction by symbiont of host innate immune response +namespace: biological_process +alt_id: GO:0052166 +alt_id: GO:0052305 +alt_id: GO:0052382 +def: "The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of host innate immune response" EXACT [] +synonym: "activation by organism of host innate immunity" EXACT [] +synonym: "activation by symbiont of host innate immunity" EXACT [] +synonym: "induction by organism of host innate immune response" RELATED [] +synonym: "induction by organism of innate immune response in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by symbiont of host innate immunity" EXACT [] +synonym: "induction of host innate immunity" EXACT [] +synonym: "positive regulation by symbiont of host innate immune response" RELATED [] +synonym: "positive regulation by symbiont of host innate immunity" RELATED [] +synonym: "positive regulation of host innate immune response" RELATED [] +synonym: "positive regulation of innate immune response in other organism" BROAD [] +synonym: "stimulation by symbiont of host innate immunity" RELATED [] +synonym: "up regulation by symbiont of host innate immunity" RELATED [] +synonym: "up-regulation by symbiont of host innate immunity" RELATED [] +synonym: "upregulation by symbiont of host innate immunity" EXACT [] +is_a: GO:0052559 ! induction by symbiont of host immune response + +[Term] +id: GO:0052391 +name: induction by symbiont of defense-related host calcium ion flux +namespace: biological_process +alt_id: GO:0052065 +alt_id: GO:0052265 +alt_id: GO:0052389 +def: "The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of host Ca2+ flux" EXACT [] +synonym: "activation by organism of host calcium ion flux" EXACT [] +synonym: "activation by symbiont of defense-related host calcium ion flux" EXACT [] +synonym: "induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by organism of host Ca2+ flux" EXACT [] +synonym: "positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of defense-related host Ca2+ flux" RELATED [] +synonym: "positive regulation by symbiont of defense-related host calcium ion flux" RELATED [] +synonym: "stimulation by symbiont of defense-related host calcium ion flux" RELATED [] +synonym: "up regulation by symbiont of defense-related host calcium ion flux" RELATED [] +synonym: "up-regulation by symbiont of defense-related host calcium ion flux" RELATED [] +synonym: "upregulation by symbiont of defense-related host calcium ion flux" RELATED [] +is_a: GO:0044416 ! induction by symbiont of host defense response +is_a: GO:0052162 ! modulation by symbiont of defense-related host calcium ion flux + +[Term] +id: GO:0052392 +name: obsolete induction by organism of defense-related symbiont calcium ion flux +namespace: biological_process +def: "OBSOLETE. The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont Ca2+ flux" EXACT [] +synonym: "activation by organism of symbiont calcium ion flux" EXACT [] +synonym: "induction by organism of defense-related symbiont calcium ion flux" EXACT [] +synonym: "induction by organism of symbiont Ca2+ flux" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052393 +name: obsolete induction by host of symbiont defense response +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:cc] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response. +synonym: "activation of symbiont defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052394 +name: obsolete induction by organism of defense-related symbiont cell wall thickening +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont defense-related cell wall thickening" EXACT [] +synonym: "activation by organism of symbiont defensive cell wall thickening" EXACT [] +synonym: "induction by organism of defense-related symbiont cell wall thickening" EXACT [] +synonym: "induction by organism of symbiont defensive cell wall thickening" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052395 +name: obsolete induction by organism of defense-related symbiont nitric oxide production +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense-related symbiont nitric acid production" EXACT [] +synonym: "activation by organism of defense-related symbiont NO production" EXACT [] +synonym: "induction by organism of defense-related symbiont nitric oxide production" EXACT [] +synonym: "induction by organism of defense-related symbiont NO production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052396 +name: obsolete induction by organism of symbiont non-apoptotic programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont non-apoptotic programmed cell death" EXACT [] +synonym: "induction by organism of symbiont non-apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052398 +name: obsolete induction by organism of symbiont phytoalexin production +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont phytoalexin production" EXACT [] +synonym: "induction by organism of symbiont phytoalexin production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052399 +name: obsolete induction by organism of symbiont programmed cell death +namespace: biological_process +def: "OBSOLETE. The activation by an organism of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont programmed cell death" EXACT [] +synonym: "induction by organism of symbiont programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052401 +name: obsolete induction by organism of defense-related symbiont reactive oxygen species production +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense-related symbiont active oxygen species production" EXACT [] +synonym: "activation by organism of defense-related symbiont AOS production" EXACT [] +synonym: "activation by organism of defense-related symbiont metabolic burst" EXACT [] +synonym: "activation by organism of defense-related symbiont oxidative burst" EXACT [] +synonym: "activation by organism of defense-related symbiont reactive oxidative species production" EXACT [] +synonym: "activation by organism of defense-related symbiont reactive oxygen intermediate production" EXACT [] +synonym: "activation by organism of defense-related symbiont reactive oxygen species production" EXACT [] +synonym: "activation by organism of defense-related symbiont respiratory burst" EXACT [] +synonym: "activation by organism of defense-related symbiont ROI production" EXACT [] +synonym: "activation by organism of defense-related symbiont ROS production" EXACT [] +synonym: "induction by organism of defense-related symbiont active oxygen species production" EXACT [] +synonym: "induction by organism of defense-related symbiont AOS production" EXACT [] +synonym: "induction by organism of defense-related symbiont metabolic burst" EXACT [] +synonym: "induction by organism of defense-related symbiont oxidative burst" EXACT [] +synonym: "induction by organism of defense-related symbiont reactive oxygen intermediate production" EXACT [] +synonym: "induction by organism of defense-related symbiont reactive oxygen species production" EXACT [] +synonym: "induction by organism of defense-related symbiont respiratory burst" EXACT [] +synonym: "induction by organism of defense-related symbiont ROI production" EXACT [] +synonym: "induction by organism of defense-related symbiont ROS production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052402 +name: obsolete induction by organism of symbiont resistance gene-dependent defense response +namespace: biological_process +def: "OBSOLETE. The activation by an organism of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense response in symbiont by specific elicitors" EXACT [] +synonym: "activation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "activation by organism of symbiont gene-for-gene resistance" EXACT [] +synonym: "activation by organism of symbiont resistance gene-dependent defense response" EXACT [] +synonym: "induction by organism of defense response in symbiont by specific elicitors" EXACT [] +synonym: "induction by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "induction by organism of symbiont gene-for-gene resistance" EXACT [] +synonym: "induction by organism of symbiont resistance gene-dependent defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052403 +name: negative regulation by host of symbiont catalytic activity +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by host of symbiont enzyme activity" EXACT [] +synonym: "down-regulation by host of symbiont enzyme activity" EXACT [] +synonym: "downregulation by host of symbiont enzyme activity" EXACT [] +synonym: "inhibition by host of symbiont enzyme activity" NARROW [] +synonym: "inhibition of symbiont enzyme activity" EXACT [] +synonym: "negative regulation by host of symbiont enzyme activity" EXACT [] +is_a: GO:0052199 ! negative regulation of catalytic activity in other organism involved in symbiotic interaction +is_a: GO:0052405 ! negative regulation by host of symbiont molecular function +is_a: GO:0052422 ! modulation by host of symbiont catalytic activity +intersection_of: GO:0052422 ! modulation by host of symbiont catalytic activity +intersection_of: negatively_regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0052404 +name: negative regulation by host of symbiont peptidase activity +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation by host of symbiont protease activity" NARROW [] +synonym: "down-regulation by host of symbiont protease activity" NARROW [] +synonym: "downregulation by host of symbiont protease activity" NARROW [] +synonym: "inhibition by host of symbiont protease activity" NARROW [] +synonym: "inhibition of symbiont protease activity" NARROW [] +synonym: "negative regulation by host of symbiont protease activity" NARROW [GOC:dph, GOC:tb] +is_a: GO:0052180 ! negative regulation of peptidase activity in other organism involved in symbiotic interaction +is_a: GO:0052403 ! negative regulation by host of symbiont catalytic activity +is_a: GO:0052427 ! modulation by host of symbiont peptidase activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: negatively_regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0052405 +name: negative regulation by host of symbiont molecular function +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of symbiont proteins. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "down regulation by host of symbiont protein function" EXACT [] +synonym: "down-regulation by host of symbiont protein function" EXACT [] +synonym: "downregulation by host of symbiont protein function" EXACT [] +synonym: "inhibition by host of symbiont protein function" NARROW [] +synonym: "inhibition of symbiont protein function" EXACT [] +synonym: "negative regulation by host of symbiont protein function" EXACT [GOC:dph, GOC:tb] +is_a: GO:0052204 ! negative regulation of molecular function in other organism involved in symbiotic interaction +is_a: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: negatively_regulates GO:0003674 ! molecular_function + +[Term] +id: GO:0052406 +name: metabolism by host of symbiont carbohydrate +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052416 ! metabolism by host of symbiont macromolecule + +[Term] +id: GO:0052407 +name: metabolism by organism of carbohydrate in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of carbohydrate in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044040 ! multi-organism carbohydrate metabolic process +is_a: GO:0052229 ! metabolism of macromolecule in other organism involved in symbiotic interaction + +[Term] +id: GO:0052408 +name: metabolism by host of symbiont cell wall cellulose +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate +is_a: GO:0052409 ! metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction + +[Term] +id: GO:0052409 +name: metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of cell wall cellulose in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044037 ! multi-organism cell wall macromolecule metabolic process +is_a: GO:0044043 ! multi-organism glucan metabolic process +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052541 ! plant-type cell wall cellulose metabolic process + +[Term] +id: GO:0052410 +name: metabolism by host of symbiont cell wall chitin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate +is_a: GO:0052411 ! metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction + +[Term] +id: GO:0052411 +name: metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of cell wall chitin in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0006037 ! cell wall chitin metabolic process +is_a: GO:0044037 ! multi-organism cell wall macromolecule metabolic process +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052412 +name: metabolism by host of symbiont cell wall pectin +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate +is_a: GO:0052413 ! metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction + +[Term] +id: GO:0052413 +name: metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of cell wall pectin in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044037 ! multi-organism cell wall macromolecule metabolic process +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction +is_a: GO:0052546 ! cell wall pectin metabolic process + +[Term] +id: GO:0052414 +name: metabolism by host of symbiont glucan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate +is_a: GO:0052415 ! metabolism by organism of glucan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052415 +name: metabolism by organism of glucan in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of glucan in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044043 ! multi-organism glucan metabolic process +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052416 +name: metabolism by host of symbiont macromolecule +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052229 ! metabolism of macromolecule in other organism involved in symbiotic interaction +is_a: GO:0052419 ! metabolism by host of substance in symbiont + +[Term] +id: GO:0052417 +name: metabolism by host of symbiont protein +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052416 ! metabolism by host of symbiont macromolecule +is_a: GO:0052418 ! metabolism by organism of protein in other organism involved in symbiotic interaction + +[Term] +id: GO:0052418 +name: metabolism by organism of protein in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of protein in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0052229 ! metabolism of macromolecule in other organism involved in symbiotic interaction + +[Term] +id: GO:0052419 +name: metabolism by host of substance in symbiont +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052214 ! metabolism of substance in other organism involved in symbiotic interaction + +[Term] +id: GO:0052420 +name: metabolism by host of symbiont xylan +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052406 ! metabolism by host of symbiont carbohydrate +is_a: GO:0052421 ! metabolism by organism of xylan in other organism involved in symbiotic interaction + +[Term] +id: GO:0052421 +name: metabolism by organism of xylan in other organism involved in symbiotic interaction +namespace: biological_process +def: "The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "metabolism by organism of xylan in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0044037 ! multi-organism cell wall macromolecule metabolic process +is_a: GO:0045491 ! xylan metabolic process +is_a: GO:0052407 ! metabolism by organism of carbohydrate in other organism involved in symbiotic interaction + +[Term] +id: GO:0052422 +name: modulation by host of symbiont catalytic activity +namespace: biological_process +def: "The process in which a host organism effects a change in the enzyme activity of its symbiont organism." [GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modulation by host of symbiont enzyme activity" EXACT [GOC:tb] +is_a: GO:0052203 ! modulation of catalytic activity in other organism involved in symbiotic interaction +is_a: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: regulates GO:0003824 ! catalytic activity + +[Term] +id: GO:0052424 +name: obsolete modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system +namespace: biological_process +def: "OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type III secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052425 +name: obsolete modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system +namespace: biological_process +def: "OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type II secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052426 +name: obsolete modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system +namespace: biological_process +def: "OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type IV secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052427 +name: modulation by host of symbiont peptidase activity +namespace: biological_process +def: "The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by host of symbiont protease activity" NARROW [GOC:bf] +is_a: GO:0052198 ! modulation of peptidase activity in other organism involved in symbiotic interaction +is_a: GO:0052422 ! modulation by host of symbiont catalytic activity +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0052428 +name: modulation by host of symbiont molecular function +namespace: biological_process +def: "The process in which an organism effects a change in the function of proteins in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:mtg_pamgo_17jul06, GOC:tb] +synonym: "modification by host of symbiont molecular function" EXACT [] +synonym: "modification by host of symbiont protein function" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052205 ! modulation of molecular function in other organism involved in symbiotic interaction + +[Term] +id: GO:0052429 +name: obsolete modulation by organism of symbiont B-cell mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont B-cell mediated immune response" EXACT [] +synonym: "regulation by organism of symbiont B-cell mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052430 +name: modulation by host of symbiont RNA levels +namespace: biological_process +def: "The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052249 ! modulation of RNA levels in other organism involved in symbiotic interaction + +[Term] +id: GO:0052431 +name: obsolete modulation by organism of symbiont T-cell mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a symbiont organism, where the two organisms are in a symbiotic interaction. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont T-cell mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052432 +name: obsolete modulation by organism of symbiont apoptosis +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont apoptosis" EXACT [] +synonym: "modulation by organism of symbiont apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052433 +name: modulation by organism of apoptotic process in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction." [GOC:jl, GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of apoptosis in other organism during symbiotic interaction" RELATED [GOC:dph] +synonym: "modulation by organism of apoptosis in other organism involved in symbiotic interaction" NARROW [] +synonym: "modulation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] +is_a: GO:0044532 ! modulation of apoptotic process in other organism +is_a: GO:0052248 ! modulation of programmed cell death in other organism involved in symbiotic interaction + +[Term] +id: GO:0052434 +name: obsolete modulation by organism of symbiont cell-mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont cell-based immune response" EXACT [] +synonym: "modulation by organism of symbiont cell-mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052435 +name: obsolete modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "modulation of defense-related symbiont MAPK-mediated signal transduction pathway by organism" EXACT [] +synonym: "modulation of defense-related symbiont mitogen activated protein kinase-mediated signal transduction pathway by organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052436 +name: obsolete modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the symbiont calcium-dependent protein kinase signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway" EXACT [] +synonym: "modulation by organism of defense-related symbiont CDPK pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052437 +name: obsolete modulation by organism of defense-related symbiont calcium ion flux +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont Ca2+ flux" EXACT [] +synonym: "modulation by organism of defense-related symbiont calcium ion flux" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052438 +name: obsolete modulation by organism of defense-related symbiont callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052439 +name: obsolete modulation by organism of defense-related symbiont cell wall callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont cell wall callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052440 +name: obsolete modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052442 +name: obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" EXACT [] +synonym: "modulation of defense-related symbiont JA-mediated signal transduction pathway by organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052444 +name: obsolete modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "modulation of defense-related symbiont SA-mediated signal transduction pathway by organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052446 +name: obsolete modulation by organism of defense-related symbiont cell wall thickening +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont cell wall thickening" EXACT [] +synonym: "modulation by organism of symbiont defensive cell wall thickening" RELATED [] +is_obsolete: true + +[Term] +id: GO:0052447 +name: obsolete modulation by organism of symbiont ethylene-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont ethylene-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052448 +name: obsolete modulation by organism of ethylene levels in symbiont +namespace: biological_process +def: "OBSOLETE. The alteration by an organism of the levels of ethylene in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of ethylene levels in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052450 +name: obsolete modulation by organism of induced systemic resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of induced systemic resistance in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052451 +name: obsolete modulation by organism of symbiont inflammatory response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont inflammatory response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052452 +name: obsolete modulation by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont innate immunity" EXACT [] +synonym: "modulation of symbiont innate immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052453 +name: obsolete modulation by organism of symbiont intracellular transport +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont intracellular transport" EXACT [] +synonym: "modulation of symbiont intracellular trafficking" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052454 +name: obsolete modulation by organism of symbiont jasmonic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont JA-mediated defense response" EXACT [] +synonym: "modulation by organism of symbiont jasmonic acid-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052455 +name: obsolete modulation by organism of jasmonic acid levels in symbiont +namespace: biological_process +def: "OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of jasmonic acid levels in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052457 +name: obsolete modulation by organism of defense-related symbiont nitric oxide production +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont nitric oxide production" EXACT [] +synonym: "modulation by organism of defense-related symbiont NO production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052458 +name: obsolete modulation by organism of symbiont non-apoptotic programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont non-apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052460 +name: modulation by host of nutrient release from symbiont +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052313 ! modulation of nutrient release from other organism involved in symbiotic interaction +relationship: part_of GO:0051850 ! acquisition of nutrients from symbiont + +[Term] +id: GO:0052461 +name: obsolete modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052462 +name: obsolete modulation by host of symbiont phagocytosis +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0052463 +name: obsolete modulation by organism of symbiont phytoalexin production +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont phytoalexin production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052464 +name: obsolete modulation by organism of symbiont programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont programmed cell death" EXACT [] +synonym: "modulation of symbiont HR" BROAD [] +synonym: "modulation of symbiont hypersensitive response" NARROW [] +synonym: "modulation of symbiont PCD" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052465 +name: obsolete modulation by organism of defense-related symbiont reactive oxygen species production +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense-related symbiont active oxygen species production" EXACT [] +synonym: "modulation by organism of defense-related symbiont AOS production" EXACT [] +synonym: "modulation by organism of defense-related symbiont metabolic burst" EXACT [] +synonym: "modulation by organism of defense-related symbiont oxidative burst" EXACT [] +synonym: "modulation by organism of defense-related symbiont reactive oxidative species production" EXACT [] +synonym: "modulation by organism of defense-related symbiont reactive oxygen intermediate production" EXACT [] +synonym: "modulation by organism of defense-related symbiont reactive oxygen species production" EXACT [] +synonym: "modulation by organism of defense-related symbiont respiratory burst" EXACT [] +synonym: "modulation by organism of defense-related symbiont ROI production" EXACT [] +synonym: "modulation by organism of defense-related symbiont ROS production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052466 +name: obsolete modulation by organism of symbiont resistance gene-dependent defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of defense response in symbiont by specific elicitors" EXACT [] +synonym: "modulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "modulation by organism of symbiont gene-for-gene resistance" EXACT [] +synonym: "modulation by organism of symbiont resistance gene-dependent defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052467 +name: obsolete modulation by organism of symbiont salicylic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont SA-mediated defense response" EXACT [] +synonym: "modulation by organism of symbiont salicylic acid-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052468 +name: obsolete modulation by organism of salicylic acid levels in symbiont +namespace: biological_process +def: "OBSOLETE. The alteration by an organism of the levels of salicylic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of salicylic acid levels in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052470 +name: obsolete modulation by host of symbiont signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0052471 +name: obsolete modulation by organism of systemic acquired resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of systemic acquired resistance in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052472 +name: modulation by host of symbiont transcription +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription." [GOC:mtg_pamgo_17jul06] +is_a: GO:0051851 ! modulation by host of symbiont process +is_a: GO:0052312 ! modulation of transcription in other organism involved in symbiotic interaction + +[Term] +id: GO:0052473 +name: obsolete negative regulation by organism of symbiont B-cell mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont B-cell mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052474 +name: obsolete negative regulation by organism of symbiont T-cell mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont T-cell mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052475 +name: obsolete negative regulation by organism of symbiont cell-mediated immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont cell-based immune response" EXACT [] +synonym: "negative regulation by organism of symbiont cell-mediated immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052476 +name: obsolete negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a valid biological process that occurs in nature. +synonym: "negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway" EXACT [] +synonym: "suppression by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052477 +name: obsolete negative regulation by organism of defense-related symbiont callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the symbiont as part of its defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of defense-related symbiont callose deposition" EXACT [] +synonym: "suppression by organism of defense-related symbiont callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052478 +name: obsolete negative regulation by organism of defense-related symbiont cell wall callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a valid biological process that occurs in nature. +synonym: "negative regulation by organism of defense-related symbiont cell wall callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052479 +name: obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway" EXACT [] +synonym: "suppression by organism of defense-related symbiont ethylene-mediated signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052480 +name: obsolete negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of defense-related symbiont JA-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052481 +name: obsolete negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative modulation by organism of defense-related symbiont SA-mediated signal transduction pathway" EXACT [] +synonym: "negative modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related symbiont SA-mediated signal transduction pathway" EXACT [] +synonym: "negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052482 +name: defense response by cell wall thickening +namespace: biological_process +def: "A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism." [GOC:mtg_pamgo_17jul06] +synonym: "cell wall thickening during defense response" RELATED [GOC:dph] +is_a: GO:0006952 ! defense response +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0052386 ! cell wall thickening + +[Term] +id: GO:0052484 +name: obsolete negative regulation by organism of symbiont ethylene-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont ethylene-mediated defense response" EXACT [] +synonym: "suppression by organism of symbiont ethylene-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052485 +name: obsolete negative regulation by organism of symbiont inflammatory response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont inflammatory response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052486 +name: obsolete negative regulation by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the symbiont organism, the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont innate immunity" EXACT [] +synonym: "negative regulation of symbiont innate immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052487 +name: obsolete negative regulation by organism of symbiont jasmonic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont jasmonic acid-mediated defense response" EXACT [] +synonym: "suppression by organism of symbiont JA-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052488 +name: obsolete negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity" EXACT [] +synonym: "suppression of general elicitor induced symbiont innate immunity" EXACT [] +synonym: "suppression of general elicitor-induced symbiont innate immunity" EXACT [] +synonym: "suppression of MAMP induced symbiont innate immunity" EXACT [] +synonym: "suppression of MAMP-induced symbiont innate immunity" EXACT [] +synonym: "suppression of PAMP induced symbiont innate immunity" EXACT [] +synonym: "suppression of PAMP-induced symbiont innate immunity" EXACT [] +synonym: "suppression of pathogen-associated molecular pattern-induced symbiont innate immunity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052489 +name: negative regulation by host of symbiont programmed cell death +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by host of symbiont programmed cell death" EXACT [] +synonym: "down-regulation by host of symbiont programmed cell death" EXACT [] +synonym: "downregulation by host of symbiont programmed cell death" EXACT [] +synonym: "inhibition by host of symbiont programmed cell death" NARROW [] +synonym: "inhibition of symbiont programmed cell death" EXACT [] +is_a: GO:0052490 ! negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction + +[Term] +id: GO:0052490 +name: negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "down-regulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "downregulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "inhibition by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] +synonym: "inhibition of programmed cell death in other organism" EXACT [] +synonym: "negative regulation by organism of programmed cell death in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0052248 ! modulation of programmed cell death in other organism involved in symbiotic interaction + +[Term] +id: GO:0052491 +name: obsolete negative regulation by organism of symbiont salicylic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont salicylic acid-mediated defense response" EXACT [] +synonym: "negative regulation of symbiont SA-mediated defense response" EXACT [] +synonym: "suppression by organism of symbiont salicylic acid-mediated defense response" EXACT [] +synonym: "suppression of symbiont SA mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052492 +name: obsolete negative regulation by host of symbiont signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "down regulation by host of symbiont signal transduction pathway" EXACT [] +synonym: "down-regulation by host of symbiont signal transduction pathway" EXACT [] +synonym: "downregulation by host of symbiont signal transduction pathway" EXACT [] +synonym: "inhibition by host of symbiont signal transduction pathway" NARROW [] +synonym: "negative modulation by organism of symbiont signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052494 +name: occlusion by host of symbiont vascular system +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, http://www.thefreedictionary.com] +is_a: GO:0052183 ! modification by host of symbiont structure +is_a: GO:0052495 ! occlusion by organism of vascular system in other organism involved in symbiotic interaction + +[Term] +id: GO:0052495 +name: occlusion by organism of vascular system in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, http://www.thefreedictionary.com] +synonym: "occlusion by organism of vascular system in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052185 ! modification of structure of other organism involved in symbiotic interaction + +[Term] +id: GO:0052496 +name: occlusion by host of symbiont xylem +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +is_a: GO:0052494 ! occlusion by host of symbiont vascular system +is_a: GO:0052497 ! occlusion by organism of xylem in other organism involved in symbiotic interaction + +[Term] +id: GO:0052497 +name: occlusion by organism of xylem in other organism involved in symbiotic interaction +namespace: biological_process +def: "The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "occlusion by organism of xylem in other organism during symbiotic interaction" RELATED [GOC:dph] +is_a: GO:0052495 ! occlusion by organism of vascular system in other organism involved in symbiotic interaction + +[Term] +id: GO:0052498 +name: obsolete pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "general elicitor-dependent activation of symbiont innate immunity" EXACT [] +synonym: "general elicitor-dependent induction of symbiont innate immunity" EXACT [] +synonym: "MAMP dependent activation of symbiont innate immunity" EXACT [] +synonym: "MAMP dependent induction of symbiont innate immunity" EXACT [] +synonym: "PAMP dependent activation of symbiont innate immunity" EXACT [] +synonym: "PAMP dependent induction of symbiont innate immunity" EXACT [] +synonym: "pathogen-associated molecular pattern dependent activation by organism of symbiont innate immunity" EXACT [] +synonym: "pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052499 +name: obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. This term was not defined before being made obsolete." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052500 +name: obsolete positive regulation by organism of symbiont apoptosis +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont apoptosis" EXACT [] +synonym: "positive regulation by organism of symbiont apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052501 +name: positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction +namespace: biological_process +alt_id: GO:0052388 +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction." [GOC:jl, GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of apoptosis in other organism during symbiotic interaction" NARROW [] +synonym: "activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "induction by organism of apoptosis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "induction by organism of apoptosis in other organism involved in symbiotic interaction" EXACT [] +synonym: "induction by organism of apoptotic programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "positive regulation by organism of apoptosis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive regulation by organism of apoptosis in other organism involved in symbiotic interaction" NARROW [] +synonym: "positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction" NARROW [] +synonym: "positive regulation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" RELATED [] +synonym: "stimulation by organism of apoptosis in other organism during symbiotic interaction" NARROW [] +synonym: "up regulation by organism of apoptosis in other organism during symbiotic interaction" RELATED [] +synonym: "up-regulation by organism of apoptosis in other organism during symbiotic interaction" RELATED [] +synonym: "upregulation by organism of apoptosis in other organism during symbiotic interaction" RELATED [] +is_a: GO:0044533 ! positive regulation of apoptotic process in other organism +is_a: GO:0052151 ! positive regulation by symbiont of host apoptotic process + +[Term] +id: GO:0052502 +name: obsolete positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "activation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "activation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway" EXACT [] +synonym: "stimulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway" NARROW [] +synonym: "up regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "up-regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052503 +name: obsolete positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the symbiont calcium-dependent protein kinase pathway during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway" EXACT [] +synonym: "positive regulation of defense-related symbiont CDPK pathway by organism" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052504 +name: obsolete positive regulation by organism of defense-related symbiont callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "induction by organism of defense-related papilla formation in symbiont" NARROW [] +synonym: "induction by organism of defense-related symbiont callose deposition" NARROW [] +synonym: "positive regulation by organism of defense-related papilla formation in symbiont" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052505 +name: obsolete positive regulation by organism of defense-related symbiont cell wall callose deposition +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "induction by organism of defense-related symbiont cell wall callose deposition" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont cell wall callose deposition" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052506 +name: obsolete positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense-related symbiont ethylene-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont ethylene-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052507 +name: obsolete positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "activation by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052508 +name: obsolete positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "activation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "induction by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" EXACT [] +synonym: "upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway" NARROW [] +synonym: "upregulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052511 +name: obsolete positive regulation by organism of symbiont ethylene-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "activation by organism of symbiont ethylene-mediated defense response" NARROW [] +synonym: "induction by organism of symbiont ethylene-mediated defense response" NARROW [] +synonym: "positive regulation by organism of symbiont ethylene-mediated defense response" EXACT [] +synonym: "upregulation by organism of symbiont ethylene-mediated defense response" NARROW [] +is_obsolete: true + +[Term] +id: GO:0052512 +name: obsolete positive regulation by organism of hormone or growth regulator levels in symbiont +namespace: biological_process +def: "OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive modulation of hormone or growth regulator levels in symbiont" EXACT [] +synonym: "positive regulation by organism of hormone or growth regulator levels in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052514 +name: obsolete positive regulation by organism of symbiont inflammatory response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont inflammatory response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052515 +name: obsolete positive regulation by organism of symbiont innate immunity +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont innate immunity" EXACT [] +synonym: "positive regulation of symbiont innate immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052516 +name: obsolete positive regulation by organism of symbiont jasmonic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "induction by organism of symbiont JA-mediated defense response" NARROW [] +synonym: "induction by organism of symbiont jasmonic acid-mediated defense response" NARROW [] +synonym: "positive regulation by organism of symbiont JA-mediated defense response" EXACT [] +synonym: "positive regulation by organism of symbiont jasmonic acid-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052517 +name: obsolete positive regulation by organism of symbiont non-apoptotic programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont non-apoptotic programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052519 +name: positive regulation by host of nutrient release from symbiont +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by host of nutrient release from symbiont" NARROW [] +synonym: "promotion of nutrient release from symbiont" EXACT [] +synonym: "stimulation by host of nutrient release from symbiont" NARROW [] +synonym: "up regulation by host of nutrient release from symbiont" EXACT [] +synonym: "up-regulation by host of nutrient release from symbiont" EXACT [] +synonym: "upregulation by host of nutrient release from symbiont" EXACT [] +is_a: GO:0052460 ! modulation by host of nutrient release from symbiont +is_a: GO:0052520 ! positive regulation by organism of nutrient release from other organism involved in symbiotic interaction + +[Term] +id: GO:0052520 +name: positive regulation by organism of nutrient release from other organism involved in symbiotic interaction +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by organism of nutrient release from other organism during symbiotic interaction" NARROW [] +synonym: "positive regulation by organism of nutrient release from other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "promotion of nutrient release from other organism" EXACT [] +synonym: "stimulation by organism of nutrient release from other organism during symbiotic interaction" NARROW [] +synonym: "up regulation by organism of nutrient release from other organism during symbiotic interaction" RELATED [] +synonym: "up-regulation by organism of nutrient release from other organism during symbiotic interaction" RELATED [] +synonym: "upregulation by organism of nutrient release from other organism during symbiotic interaction" RELATED [] +is_a: GO:0052313 ! modulation of nutrient release from other organism involved in symbiotic interaction + +[Term] +id: GO:0052521 +name: obsolete positive regulation by host of symbiont phagocytosis +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "activation by host of symbiont phagocytosis" NARROW [] +synonym: "stimulation by host of symbiont phagocytosis" NARROW [] +synonym: "up regulation by host of symbiont phagocytosis" EXACT [] +synonym: "up-regulation by host of symbiont phagocytosis" EXACT [] +synonym: "upregulation by host of symbiont phagocytosis" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052522 +name: obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "activation by organism of phagocytosis in other organism during symbiotic interaction" NARROW [] +synonym: "positive regulation by organism of phagocytosis in other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "stimulation by organism of phagocytosis in other organism during symbiotic interaction" NARROW [] +synonym: "up regulation by organism of phagocytosis in other organism during symbiotic interaction" RELATED [] +synonym: "up-regulation by organism of phagocytosis in other organism during symbiotic interaction" RELATED [] +synonym: "upregulation by organism of phagocytosis in other organism during symbiotic interaction" RELATED [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18562 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0052523 +name: obsolete positive regulation by organism of symbiont programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "enhancement or induction of symbiont programmed cell death" EXACT [] +synonym: "positive regulation by organism of symbiont programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052524 +name: obsolete positive regulation by organism of symbiont salicylic acid-mediated defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "induction by organism of symbiont SA-mediated defense response" NARROW [] +synonym: "induction by organism of symbiont salicylic acid-mediated defense response" NARROW [] +synonym: "positive regulation by organism of symbiont SA-mediated defense response" EXACT [] +synonym: "positive regulation by organism of symbiont salicylic acid-mediated defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052525 +name: obsolete positive regulation by host of symbiont signal transduction pathway +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "activation by host of symbiont signal transduction pathway" NARROW [] +synonym: "stimulation by host of symbiont signal transduction pathway" NARROW [] +synonym: "up regulation by host of symbiont signal transduction pathway" EXACT [] +synonym: "up-regulation by host of symbiont signal transduction pathway" EXACT [] +synonym: "upregulation by host of symbiont signal transduction pathway" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052528 +name: obsolete upregulation by organism of symbiont programmed cell death +namespace: biological_process +def: "OBSOLETE. Any process by which an organism increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "enhancement of symbiont programmed cell death by organism" EXACT [] +synonym: "upregulation by organism of symbiont programmed cell death" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052530 +name: obsolete positive regulation by organism of symbiont resistance gene-dependent defense response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense response in symbiont by specific elicitors" EXACT [] +synonym: "positive regulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont" EXACT [] +synonym: "positive regulation by organism of symbiont gene-for-gene resistance" EXACT [] +synonym: "positive regulation by organism of symbiont resistance gene-dependent defense response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052531 +name: obsolete positive regulation by organism of defense-related symbiont calcium ion flux +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense-related symbiont Ca2+ flux" EXACT [] +synonym: "positive regulation by organism of defense-related symbiont calcium ion flux" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052534 +name: obsolete positive regulation by organism of induced systemic resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of induced systemic resistance in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052536 +name: obsolete positive regulation by organism of systemic acquired resistance in symbiont +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of systemic acquired resistance in symbiont" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052540 +name: obsolete positive regulation by organism of defense-related symbiont cell wall thickening +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of defense-related symbiont cell wall thickening" EXACT [] +synonym: "positive regulation by organism of symbiont defensive cell wall thickening" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052541 +name: plant-type cell wall cellulose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall." [GOC:mah, ISBN:0198506732] +synonym: "cell wall cellulose metabolism" EXACT [] +synonym: "cellulose and pectin-containing cell wall cellulose metabolic process" EXACT [] +is_a: GO:0030243 ! cellulose metabolic process +is_a: GO:0034406 ! cell wall beta-glucan metabolic process +relationship: part_of GO:0009664 ! plant-type cell wall organization + +[Term] +id: GO:0052542 +name: defense response by callose deposition +namespace: biological_process +def: "Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls." [GOC:mtg_pamgo_17jul06] +synonym: "callose deposition during defense response" RELATED [GOC:dph] +synonym: "callose localization during defense response" RELATED [] +is_a: GO:0006952 ! defense response +is_a: GO:0052545 ! callose localization + +[Term] +id: GO:0052543 +name: callose deposition in cell wall +namespace: biological_process +def: "Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls." [GOC:mtg_pamgo_17jul06] +synonym: "callose localization in cell wall" EXACT [] +synonym: "cell wall callose deposition" EXACT [] +synonym: "cell wall callose localization" EXACT [] +is_a: GO:0052386 ! cell wall thickening +is_a: GO:0052545 ! callose localization +is_a: GO:0070727 ! cellular macromolecule localization + +[Term] +id: GO:0052544 +name: defense response by callose deposition in cell wall +namespace: biological_process +def: "Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls." [GOC:mtg_pamgo_17jul06] +synonym: "callose deposition in cell wall during defense response" RELATED [GOC:dph] +synonym: "callose localization in cell wall during defense response" EXACT [] +synonym: "cell wall callose deposition during defense response" EXACT [] +synonym: "cell wall callose localization during defense response" EXACT [] +is_a: GO:0052482 ! defense response by cell wall thickening +is_a: GO:0052542 ! defense response by callose deposition +is_a: GO:0052543 ! callose deposition in cell wall +intersection_of: GO:0052543 ! callose deposition in cell wall +intersection_of: part_of GO:0006952 ! defense response +relationship: part_of GO:0006952 ! defense response + +[Term] +id: GO:0052545 +name: callose localization +namespace: biological_process +def: "Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls." [GOC:mtg_pamgo_17jul06, PMID:18397379] +synonym: "callose localisation" EXACT [GOC:mah] +is_a: GO:0033037 ! polysaccharide localization + +[Term] +id: GO:0052546 +name: cell wall pectin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall." [GOC:ai] +synonym: "cell wall pectin metabolism" EXACT [] +synonym: "cellulose and pectin-containing cell wall pectin metabolic process" EXACT [] +synonym: "pectin metabolism during cell wall biogenesis" EXACT [] +synonym: "plant-type cell wall pectin metabolic process" EXACT [] +is_a: GO:0045488 ! pectin metabolic process +relationship: part_of GO:0009664 ! plant-type cell wall organization + +[Term] +id: GO:0052547 +name: regulation of peptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:ai] +synonym: "peptidase regulator activity" RELATED [] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008233 ! peptidase activity +relationship: regulates GO:0008233 ! peptidase activity + +[Term] +id: GO:0052548 +name: regulation of endopeptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:ai, GOC:hjd] +synonym: "protease regulator activity" NARROW [] +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004175 ! endopeptidase activity +relationship: regulates GO:0004175 ! endopeptidase activity + +[Term] +id: GO:0052553 +name: modulation by symbiont of host immune response +namespace: biological_process +alt_id: GO:0052552 +def: "Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "modulation by organism of immune response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052572 ! response to host immune response +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0052554 +name: obsolete modulation by organism of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "modulation by organism of symbiont immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052557 +name: obsolete positive regulation by organism of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "positive regulation by organism of symbiont immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052559 +name: induction by symbiont of host immune response +namespace: biological_process +alt_id: GO:0052555 +alt_id: GO:0052556 +alt_id: GO:0052558 +def: "Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "activation by symbiont of host immune response" EXACT [] +synonym: "induction by organism of immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by organism of immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "positive regulation by symbiont of host immune response" RELATED [] +synonym: "stimulation by symbiont of host immune response" RELATED [] +synonym: "up regulation by symbiont of host immune response" RELATED [] +synonym: "up-regulation by symbiont of host immune response" RELATED [] +synonym: "upregulation by symbiont of host immune response" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052560 +name: obsolete induction by organism of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism activates the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "induction by organism of symbiont immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052562 +name: suppression by symbiont of host immune response +namespace: biological_process +alt_id: GO:0052561 +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "down regulation by symbiont of host immune response" EXACT [] +synonym: "down-regulation by symbiont of host immune response" EXACT [] +synonym: "downregulation by symbiont of host immune response" EXACT [] +synonym: "inhibition by symbiont of host immune response" NARROW [] +synonym: "negative regulation by organism of immune response of other organism involved in symbiotic interaction" BROAD [] +synonym: "negative regulation by symbiont of host immune response" EXACT [] +is_a: GO:0052553 ! modulation by symbiont of host immune response + +[Term] +id: GO:0052563 +name: obsolete negative regulation by organism of symbiont immune response +namespace: biological_process +def: "OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "negative regulation by organism of symbiont immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052568 +name: obsolete response to symbiont phytoalexin production +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "response to symbiont phytoalexin production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052569 +name: obsolete response to defense-related symbiont nitric oxide production +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "response to defense-related symbiont nitric oxide production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052570 +name: obsolete response to defense-related symbiont reactive oxygen species production +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "response to defense-related symbiont reactive oxygen species production" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052571 +name: obsolete response to symbiont immune response +namespace: biological_process +def: "OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo] +comment: This term was made obsolete because it does not represent a real biological process. +synonym: "response to symbiont immune response" EXACT [] +is_obsolete: true + +[Term] +id: GO:0052572 +name: response to host immune response +namespace: biological_process +alt_id: GO:0052564 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] +synonym: "response to immune response of other organism involved in symbiotic interaction" BROAD [] +is_a: GO:0052200 ! response to host defenses + +[Term] +id: GO:0052573 +name: UDP-D-galactose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "UDP-D-galactopyranose metabolic process" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-D-galactopyranose metabolism" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-D-galactose metabolism" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-galactose metabolic process" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-galactose metabolism" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "uridine diphosphate galactose metabolic process" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "uridine diphosphate galactose metabolism" EXACT [MetaCyc:UDP-GALACTOSE] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process +creation_date: 2010-07-23T03:29:57Z + +[Term] +id: GO:0052574 +name: UDP-galactose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate." [GOC:ai] +synonym: "UDP-D-galactopyranose biosynthesis" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-D-galactopyranose biosynthetic process" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-D-galactose biosynthesis" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-D-galactose biosynthetic process" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "UDP-galactose biosynthesis" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "uridine diphosphate galactose biosynthesis" EXACT [MetaCyc:UDP-GALACTOSE] +synonym: "uridine diphosphate galactose biosynthetic process" EXACT [MetaCyc:UDP-GALACTOSE] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0052573 ! UDP-D-galactose metabolic process +creation_date: 2010-07-23T03:52:40Z + +[Term] +id: GO:0052575 +name: carbohydrate localization +namespace: biological_process +def: "Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah] +synonym: "carbohydrate localisation" EXACT [PMID:10758476] +is_a: GO:0033036 ! macromolecule localization +creation_date: 2010-07-23T04:08:13Z + +[Term] +id: GO:0052576 +name: carbohydrate storage +namespace: biological_process +def: "The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [PMID:10758476] +is_a: GO:0052575 ! carbohydrate localization +creation_date: 2010-07-23T04:16:56Z + +[Term] +id: GO:0052577 +name: germacrene-D synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate." [EC:4.2.3.22] +synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity" EXACT [EC:4.2.3.22] +xref: EC:4.2.3.22 +xref: KEGG_REACTION:R07648 +xref: MetaCyc:RXN-8562 +is_a: GO:0010334 ! sesquiterpene synthase activity +created_by: ai +creation_date: 2010-08-09T01:39:02Z + +[Term] +id: GO:0052578 +name: alpha-farnesene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate." [MetaCyc:RXN-8574] +synonym: "(E,E)-alpha-farnesene synthase activity" EXACT [MetaCyc:RXN-8574] +xref: MetaCyc:RXN-8574 +is_a: GO:0010334 ! sesquiterpene synthase activity +created_by: ai +creation_date: 2010-08-09T01:39:42Z + +[Term] +id: GO:0052579 +name: (+)-pulegone reductase, (+)-isomenthone as substrate, activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+." [EC:1.3.1.81, MetaCyc:RXN-5164] +synonym: "(+)-isomenthone:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.81] +xref: EC:1.3.1.81 +xref: MetaCyc:RXN-5164 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2010-08-09T04:28:00Z + +[Term] +id: GO:0052580 +name: (+)-pulegone reductase, (-)-menthone as substrate, activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+." [EC:1.3.1.81, MetaCyc:RXN-5163] +synonym: "(-)-menthone:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.81] +xref: EC:1.3.1.81 +xref: MetaCyc:RXN-5164 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2010-08-09T04:33:53Z + +[Term] +id: GO:0052581 +name: (-)-isopiperitenone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+)." [EC:1.3.1.82, RHEA:25651] +synonym: "(+)-cis-isopulegone:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.82] +xref: EC:1.3.1.82 +xref: KEGG_REACTION:R06417 +xref: MetaCyc:RXN-5161 +xref: RHEA:25651 +is_a: GO:0035671 ! enone reductase activity +created_by: ai +creation_date: 2010-08-09T04:42:05Z + +[Term] +id: GO:0052582 +name: (+)-menthofuran synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+)." [EC:1.14.14.143, RHEA:25658] +synonym: "(+)-MFS activity" BROAD [EC:1.14.13.104] +synonym: "(+)-pulegone 9-hydroxylase activity" EXACT [EC:1.14.14.143] +synonym: "(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity" EXACT [EC:1.14.14.143] +synonym: "cytochrome P450 menthofuran synthase activity" EXACT [EC:1.14.14.143] +synonym: "menthofuran synthase activity" EXACT [EC:1.14.14.143] +xref: EC:1.14.14.143 +xref: KEGG_REACTION:R08923 +xref: MetaCyc:1.14.13.104-RXN +xref: RHEA:25658 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: ai +creation_date: 2010-08-09T04:47:42Z + +[Term] +id: GO:0052583 +name: oxidoreductase activity, acting on halogen in donors +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:mah] +xref: EC:1.22 +is_a: GO:0016491 ! oxidoreductase activity +creation_date: 2010-08-13T10:14:12Z + +[Term] +id: GO:0052584 +name: oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:mah] +xref: EC:1.22.1 +is_a: GO:0052583 ! oxidoreductase activity, acting on halogen in donors +created_by: ai +creation_date: 2010-08-13T10:17:56Z + +[Term] +id: GO:0052585 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound." [GOC:ai] +xref: EC:1.4.5 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors +creation_date: 2010-08-13T10:29:06Z + +[Term] +id: GO:0052586 +name: oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound." [GOC:jl] +xref: EC:1.7.5 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors +created_by: ai +creation_date: 2010-08-13T10:34:37Z + +[Term] +id: GO:0052587 +name: diacetyl reductase ((R)-acetoin forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH." [EC:1.1.1.303, RHEA:22900] +synonym: "(R)-acetoin dehydrogenase activity" EXACT [EC:1.1.1.303] +xref: EC:1.1.1.303 +xref: KEGG_REACTION:R02855 +xref: MetaCyc:RXN-11036 +xref: RHEA:22900 +is_a: GO:0019152 ! acetoin dehydrogenase activity + +[Term] +id: GO:0052588 +name: diacetyl reductase ((S)-acetoin forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH." [EC:1.1.1.304, RHEA:27286] +synonym: "(S)-acetoin dehydrogenase activity" EXACT [EC:1.1.1.304] +xref: EC:1.1.1.304 +xref: KEGG_REACTION:R09078 +xref: MetaCyc:RXN-11032 +xref: RHEA:27286 +is_a: GO:0019152 ! acetoin dehydrogenase activity + +[Term] +id: GO:0052589 +name: malate dehydrogenase (menaquinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol." [MetaCyc:RXNI-3] +synonym: "(S)-malate:(menaquinone) oxidoreductase activity" EXACT [EC:1.1.5.4] +synonym: "(S)-malate:menaquinone oxidoreductase activity" EXACT [EC:1.1.5.4] +xref: EC:1.1.5.4 +xref: MetaCyc:RXNI-3 +is_a: GO:0016615 ! malate dehydrogenase activity +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0052590 +name: sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol." [MetaCyc:RXN0-5258] +comment: Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591. +xref: EC:1.1.5.3 +xref: MetaCyc:RXN0-5258 +is_a: GO:0004368 ! glycerol-3-phosphate dehydrogenase (quinone) activity + +[Term] +id: GO:0052591 +name: sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8." [MetaCyc:GLYC3PDEHYDROG-RXN] +comment: Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591. +xref: EC:1.1.5.3 +xref: MetaCyc:GLYC3PDEHYDROG-RXN +is_a: GO:0052590 ! sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity + +[Term] +id: GO:0052592 +name: oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:ai] +synonym: "oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor" EXACT [] +xref: EC:1.17.7 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0052593 +name: tryptamine:oxygen oxidoreductase (deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+." [MetaCyc:RXN-1401] +xref: EC:1.4.3.21 +xref: KEGG_REACTION:R02173 +xref: MetaCyc:RXN-1401 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052594 +name: aminoacetone:oxygen oxidoreductase(deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+." [MetaCyc:AMACETOXID-RXN] +xref: EC:1.4.3.21 +xref: KEGG_REACTION:R02529 +xref: MetaCyc:AMACETOXID-RXN +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052595 +name: aliphatic-amine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:AMINEOXID-RXN] +synonym: "aliphatic-amine:oxygen oxidoreductase(deaminating) activity" EXACT [] +xref: EC:1.4.3.21 +xref: MetaCyc:AMINEOXID-RXN +xref: RHEA:16153 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052596 +name: phenethylamine:oxygen oxidoreductase (deaminating) activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:AMINEPHEN-RXN] +xref: EC:1.4.3.21 +xref: KEGG_REACTION:R02613 +xref: MetaCyc:AMINEPHEN-RXN +xref: RHEA:25265 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052597 +name: diamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide." [MetaCyc:RXN-9599] +synonym: "diamine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.22] +xref: EC:1.4.3.22 +xref: MetaCyc:RXN-9599 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052598 +name: histamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-9600] +synonym: "1H-Imidazole-4-ethanamine oxidase activity" EXACT [KEGG_REACTION:R02150] +synonym: "1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity" EXACT [KEGG_REACTION:R02150] +synonym: "histamine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.22] +xref: EC:1.4.3.22 +xref: KEGG_REACTION:R02150 +xref: MetaCyc:RXN-9600 +xref: Reactome:R-HSA-5696131 "AOC1 deaminates Hist" +xref: RHEA:25625 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052599 +name: methylputrescine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-8244] +synonym: "N-methylputrescine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.22] +xref: EC:1.4.3.22 +xref: KEGG_REACTION:R05334 +xref: MetaCyc:RXN-8244 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052600 +name: propane-1,3-diamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+." [MetaCyc:RXN-6381] +synonym: "1,3-diaminopropane oxidase activity" EXACT [KEGG:C00986] +synonym: "propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.3.22] +synonym: "trimethylenediamine oxidase activity" EXACT [CHEBI:15725] +xref: EC:1.4.3.22 +xref: KEGG_REACTION:R03139 +xref: MetaCyc:RXN-6381 +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + +[Term] +id: GO:0052601 +name: (S)-limonene 1,2-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide." [MetaCyc:RXN-9409] +synonym: "(-)-limonene 1,2-monooxygenase activity" EXACT [EC:1.14.13.107] +synonym: "(-)-limonene,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.13.107] +synonym: "(S)-limonene,NAD(P)H:oxygen oxidoreductase activity" EXACT systematic_synonym [EC:1.14.13.107] +xref: EC:1.14.13.107 +xref: KEGG_REACTION:R09385 "(S)-limonene,NADH:oxygen oxidoreductase" +xref: KEGG_REACTION:R09389 "(S)-limonene,NADPH:oxygen oxidoreductase" +xref: MetaCyc:RXN-9409 +xref: RHEA:26085 +xref: RHEA:26089 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0052602 +name: 4-chloronitrobenzene nitroreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O." [MetaCyc:RXN-8833] +xref: MetaCyc:RXN-8833 +xref: UM-BBD_enzymeID:e0245 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0052603 +name: 1-chloro-4-nitrosobenzene nitroreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O." [MetaCyc:RXN-8834] +xref: MetaCyc:RXN-8834 +xref: UM-BBD_enzymeID:e0245 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0052604 +name: delta-tocopherol cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol." [MetaCyc:RXN-2561, PMID:12213958] +xref: KEGG_REACTION:R07503 +xref: MetaCyc:RXN-2561 +is_a: GO:0009975 ! cyclase activity + +[Term] +id: GO:0052605 +name: gamma-tocopherol cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol." [MetaCyc:RXN-2543, PMID:12213958] +xref: KEGG_REACTION:R07502 +xref: MetaCyc:RXN-2543 +is_a: GO:0009975 ! cyclase activity + +[Term] +id: GO:0052606 +name: chlorophyllide a oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O." [EC:1.13.12.14, MetaCyc:RXN-7676] +synonym: "CAO activity" BROAD [EC:1.13.12.14] +synonym: "chlorophyll a oxygenase activity" EXACT [] +synonym: "chlorophyllide a:oxygen 7-oxidoreductase activity" EXACT [EC:1.13.12.14] +synonym: "chlorophyllide-a oxygenase activity" EXACT [EC:1.13.12.14] +xref: KEGG_REACTION:R08203 +xref: MetaCyc:RXN-7676 +xref: RHEA:22676 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +relationship: part_of GO:0010277 ! chlorophyllide a oxygenase [overall] activity + +[Term] +id: GO:0052607 +name: 7-hydroxy-chlorophyllide a oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O." [EC:1.13.12.14, MetaCyc:RXN-7677] +synonym: "7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity" EXACT [EC:1.13.12.14] +synonym: "7-hydroxychlorophyllide-a oxygenase activity" EXACT [EC:1.13.12.14] +synonym: "CAO activity" BROAD [EC:1.13.12.14] +synonym: "chlorophyll b synthetase activity" EXACT [] +synonym: "chlorophyll-b synthase activity" EXACT [EC:1.13.12.14] +xref: KEGG_REACTION:R08204 +xref: MetaCyc:RXN-7677 +xref: RHEA:22136 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +relationship: part_of GO:0010277 ! chlorophyllide a oxygenase [overall] activity + +[Term] +id: GO:0052608 +name: echinenone 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8214] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "beta-ring carotenoid 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8214 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052609 +name: 4-ketotorulene 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8218] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "beta-ring carotenoid 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8218 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052610 +name: beta-cryptoxanthin hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8026] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "beta-ring carotenoid 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8026 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052611 +name: beta-carotene 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8025] +synonym: "beta-carotene 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8025 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052612 +name: adonirubin 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8187] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "beta-ring carotenoid 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8187 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052613 +name: canthaxanthin 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O." [MetaCyc:RXN-8186] +synonym: "beta-carotene hydroxylase activity" BROAD [] +synonym: "beta-ring carotenoid 3-hydroxylase activity" BROAD [MetaCyc:MONOMER-12386] +synonym: "carotene beta-ring hydroxylase activity" BROAD [] +xref: EC:1.14.99 +xref: MetaCyc:RXN-8186 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052614 +name: uracil oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate." [MetaCyc:RXN0-6444, PMID:20369853, PMID:20400551] +synonym: "pyrimidine oxygenase activity" BROAD [MetaCyc:RXN0-6444] +xref: MetaCyc:RXN0-6444 +is_a: GO:0016491 ! oxidoreductase activity +creation_date: 2010-08-26T10:11:11Z + +[Term] +id: GO:0052615 +name: ent-kaurene oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol." [MetaCyc:1.14.13.78-RXN] +xref: EC:1.14.14.86 +xref: MetaCyc:1.14.13.78-RXN +xref: RHEA:32323 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052616 +name: ent-kaur-16-en-19-ol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al." [MetaCyc:RXN-5242] +xref: EC:1.14.14.86 +xref: MetaCyc:RXN-5242 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052617 +name: ent-kaur-16-en-19-al oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate." [MetaCyc:RXN-7580] +xref: EC:1.14.14.86 +xref: MetaCyc:RXN-7580 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052618 +name: coenzyme F420-0:L-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate." [MetaCyc:RXN-8080] +xref: EC:6.3.2.31 +xref: MetaCyc:RXN-8080 +xref: RHEA:30555 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052619 +name: coenzyme F420-1:gamma-L-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate." [MetaCyc:RXN-8081] +xref: EC:6.3.2.34 +xref: MetaCyc:RXN-8081 +xref: RHEA:30523 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052620 +name: thymine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2." [MetaCyc:RXN-8646] +xref: EC:1.17.99.4 +xref: MetaCyc:RXN-8646 +is_a: GO:0016725 ! oxidoreductase activity, acting on CH or CH2 groups + +[Term] +id: GO:0052621 +name: diguanylate cyclase activity +namespace: molecular_function +alt_id: GO:0043789 +def: "Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+)." [EC:2.7.7.65, RHEA:24898] +synonym: "GTP:GTP guanylyltransferase activity" BROAD [EC:2.7.7.65] +xref: EC:2.7.7.65 +xref: KEGG_REACTION:R08057 +xref: MetaCyc:RXN0-5359 +xref: RHEA:24898 +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0052622 +name: ATP dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate." [EC:2.5.1.27, MetaCyc:RXN-4303] +synonym: "2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity" EXACT [] +synonym: "2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity" EXACT [KEGG_REACTION:R08052] +synonym: "ATP isopentenyltransferase activity" EXACT [] +synonym: "dimethylallyl-diphosphate:ATP dimethylallyltransferase activity" EXACT [EC:2.5.1.27] +xref: EC:2.5.1 +xref: KEGG_REACTION:R08052 +xref: MetaCyc:RXN-4303 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: ai +creation_date: 2010-08-26T10:45:38Z + +[Term] +id: GO:0052623 +name: ADP dimethylallyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate." [EC:2.5.1.27, MetaCyc:RXN-4305] +synonym: "2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity" EXACT [] +synonym: "2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity" EXACT [KEGG_REACTION:R08051] +synonym: "ADP isopentenyltransferase activity" EXACT [] +synonym: "dimethylallyl-diphosphate:ADP dimethylallyltransferase activity" EXACT [EC:2.5.1.27] +xref: EC:2.5.1 +xref: KEGG_REACTION:R08051 +xref: MetaCyc:RXN-4305 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: ai +creation_date: 2010-08-26T10:45:44Z + +[Term] +id: GO:0052624 +name: 2-phytyl-1,4-naphthoquinone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+." [MetaCyc:RXN-6723, MetaCyc:RXN-7569, PMID:14617060] +synonym: "demethylphylloquinone methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity" EXACT [] +synonym: "SA methyltransferase activity" BROAD [] +synonym: "salicylate methyltransferase activity" BROAD [] +synonym: "salicylic acid methyltransferase activity" BROAD [] +xref: KEGG_REACTION:R06859 +xref: MetaCyc:RXN-6723 +xref: MetaCyc:RXN-7569 +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0008171 ! O-methyltransferase activity +created_by: ai +creation_date: 2010-08-26T12:00:06Z + +[Term] +id: GO:0052625 +name: 4-aminobenzoate amino acid synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10884, PMID:19189963] +synonym: "4-aminobenzoyl amino acid synthetase activity" EXACT [] +synonym: "p-aminobenzoate amino acid synthetase activity" EXACT [] +synonym: "p-aminobenzoyl amino acid synthetase activity" EXACT [] +synonym: "pABA amino acid synthetase activity" EXACT [] +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052626 +name: benzoate amino acid synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10886, PMID:19189963] +synonym: "benzoyl amino acid synthetase activity" EXACT [] +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052627 +name: vanillate amino acid synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10885, PMID:19189963] +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052628 +name: 4-hydroxybenzoate amino acid synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate." [MetaCyc:RXN-10884, PMID:19189963] +synonym: "4-hydroxybenzoyl amino acid synthetase activity" EXACT [] +synonym: "4HBA amino acid synthetase activity" EXACT [] +synonym: "p-hydroxybenzoate amino acid synthetase activity" EXACT [] +synonym: "p-hydroxybenzoyl amino acid synthetase activity" EXACT [] +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0052629 +name: phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+." [MetaCyc:RXN-10958, PMID:19901554] +xref: EC:3.1.3 +xref: MetaCyc:RXN-10958 +xref: Reactome:R-HSA-1676065 "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane" +xref: Reactome:R-HSA-1676105 "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane" +xref: Reactome:R-HSA-1676203 "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane" +xref: Reactome:R-HSA-6809320 "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane" +xref: Reactome:R-HSA-6809778 "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1" +xref: Reactome:R-HSA-6809944 "PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane" +is_a: GO:0106018 ! phosphatidylinositol-3,5-bisphosphate phosphatase activity + +[Term] +id: GO:0052630 +name: UDP-N-acetylgalactosamine diphosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine." [EC:2.7.7.83, RHEA:34363] +synonym: "N-acetylgalactosamine 1-phosphate uridylyltransferase" EXACT [] +synonym: "N-acetylgalactosamine-1-phosphate uridyltransferase activity" EXACT [] +synonym: "UDP-acetylgalactosamine pyrophosphorylase activity" EXACT [] +synonym: "UDP-GalNAc pyrophosphorylase activity" EXACT [] +synonym: "UDP-N-acetylgalactosamine pyrophosphorylase activity" EXACT [] +synonym: "uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity" EXACT [] +synonym: "uridine diphosphoacetylgalactosamine phosphorylase activity" EXACT [] +synonym: "uridine diphosphoacetylgalactosamine pyrophosphorylase activity" EXACT [] +synonym: "UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity" EXACT [] +synonym: "UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity" EXACT [] +xref: EC:2.7.7.83 +xref: RHEA:34363 +is_a: GO:0070569 ! uridylyltransferase activity + +[Term] +id: GO:0052631 +name: sphingolipid delta-8 desaturase activity +namespace: molecular_function +def: "Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8)." [PMID:17600137, PMID:9786850] +xref: MetaCyc:RXN-7798 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0052633 +name: isocitrate hydro-lyase (cis-aconitate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: cis-aconitate + H2O = isocitrate." [EC:4.2.1.3, GOC:pde, GOC:vw, MetaCyc:ACONITATEHYDR-RXN] +synonym: "aconitate hydratase activity" BROAD [EC:4.2.1.3] +synonym: "cis-aconitase activity" BROAD [EC:4.2.1.3] +synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.3] +synonym: "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" BROAD [EC:4.2.1.3] +synonym: "citrate(isocitrate) hydro-lyase activity" BROAD [EC:4.2.1.3] +xref: KEGG_REACTION:R01900 +xref: MetaCyc:ACONITATEHYDR-RXN +xref: RHEA:22144 +is_a: GO:0016836 ! hydro-lyase activity +relationship: has_part GO:0003994 ! aconitate hydratase activity + +[Term] +id: GO:0052634 +name: C-19 gibberellin 2-beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons." [EC:1.14.11.13, GOC:kad] +synonym: "(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)" EXACT [] +synonym: "C(19) gibberellin 2-oxidase activity" EXACT [] +synonym: "C-19 GA 2-oxidase activity" EXACT [] +synonym: "C-19 gibberellin 2-beta-hydroxylase activity" EXACT [] +synonym: "C-19 gibberellin 2-oxidase activity" EXACT [] +synonym: "C-19 gibberellin 2beta-dioxygenase activity" EXACT [] +synonym: "C-19 gibberellin 2beta-hydroxylase activity" EXACT [] +xref: EC:1.14.11.13 +is_a: GO:0045543 ! gibberellin 2-beta-dioxygenase activity + +[Term] +id: GO:0052635 +name: C-20 gibberellin 2-beta-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons." [EC:1.14.11.13, GOC:kad] +synonym: "(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)" EXACT [] +synonym: "C(20) gibberellin 2-oxidase activity" EXACT [] +synonym: "C-20 GA 2-oxidase activity" EXACT [] +synonym: "C-20 gibberellin 2-beta-hydroxylase activity" EXACT [] +synonym: "C-20 gibberellin 2-oxidase activity" EXACT [] +synonym: "C-20 gibberellin 2beta-dioxygenase activity" EXACT [] +synonym: "C-20 gibberellin 2beta-hydroxylase activity" EXACT [] +is_a: GO:0045543 ! gibberellin 2-beta-dioxygenase activity + +[Term] +id: GO:0052636 +name: arabinosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor)." [GOC:ai] +synonym: "arabinosyl transferase activity" EXACT [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0052637 +name: delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol." [GOC:ai, MetaCyc:RXN-8319, PMID:19682287] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0052638 +name: indole-3-butyrate beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP." [MetaCyc:RXN-11655] +synonym: "IBA-Glc synthetase activity" EXACT [] +synonym: "IBA-glucose synthase activity" EXACT [] +synonym: "IBAGlu synthase activity" EXACT [] +synonym: "indol-3-ylbutyrylglucose synthase activity" EXACT [] +synonym: "indole-3-butyric acid glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity" EXACT [] +synonym: "UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity" EXACT [] +synonym: "UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity" EXACT [] +synonym: "UDPG-indol-3-ylbutyryl glucosyl transferase activity" EXACT [] +synonym: "UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity" EXACT [] +synonym: "uridine diphosphoglucose-indolebutyrate glucosyltransferase activity" EXACT [] +xref: MetaCyc:RXN-11655 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0052639 +name: salicylic acid glucosyltransferase (ester-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP." [MetaCyc:RXN-11659] +synonym: "salicylic acid glucosyltransferase activity" BROAD [MetaCyc:RXN-11659] +synonym: "UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity" EXACT [MetaCyc:RXN-11659] +synonym: "UDP:glucose:SA glucosyltransferase (ester-forming) activity" EXACT [MetaCyc:RXN-11659] +synonym: "UDP:glucose:salicylate glucosyltransferase (ester-forming) activity" EXACT [MetaCyc:RXN-11659] +synonym: "UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity" EXACT [MetaCyc:RXN-11659] +xref: MetaCyc:RXN-11659 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0052640 +name: salicylic acid glucosyltransferase (glucoside-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP." [MetaCyc:RXN-11658] +synonym: "salicylic acid glucosyltransferase activity" BROAD [MetaCyc:RXN-11658] +synonym: "UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity" EXACT [MetaCyc:RXN-11658] +synonym: "UDP:glucose:SA glucosyltransferase (glucoside-forming) activity" EXACT [MetaCyc:RXN-11658] +synonym: "UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity" EXACT [MetaCyc:RXN-11658] +synonym: "UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity" EXACT [MetaCyc:RXN-11658] +xref: MetaCyc:RXN-11658 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0052641 +name: benzoic acid glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP." [MetaCyc:RXN-11660] +synonym: "benzoate glucosyltransferase activity" EXACT [MetaCyc:RXN-11660] +synonym: "UDP:glucose:BA glucosyltransferase activity" EXACT [MetaCyc:RXN-11660] +synonym: "UDP:glucose:benzoate glucosyltransferase activity" EXACT [MetaCyc:RXN-11660] +synonym: "UDP:glucose:benzoic acid glucosyltransferase activity" EXACT [MetaCyc:RXN-11660] +xref: MetaCyc:RXN-11660 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0052642 +name: lysophosphatidic acid phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol." [PMID:20045079, PMID:7966317] +synonym: "LPA phosphatase activity" EXACT [] +synonym: "lysophosphatidate phosphatase activity" EXACT [] +xref: Reactome:R-HSA-8878654 "ACP6 hydrolyses MYS-LPA" +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0052643 +name: chlorophyllide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl." [PMID:7724548] +synonym: "chlorophyllide metabolism" EXACT [] +is_a: GO:0015994 ! chlorophyll metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process + +[Term] +id: GO:0052644 +name: chlorophyllide a metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a." [PMID:7724548] +synonym: "chlorophyllide a metabolism" EXACT [] +is_a: GO:0052643 ! chlorophyllide metabolic process + +[Term] +id: GO:0052645 +name: F420-0 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues." [GOC:curators] +synonym: "coenzyme F420-0 metabolic process" EXACT [CHEBI:59532] +synonym: "coenzyme F420-0 metabolism" EXACT [CHEBI:59532] +synonym: "F(420)-0 metabolic process" EXACT [CHEBI:59532] +synonym: "F420-0 metabolism" EXACT [] +is_a: GO:0019520 ! aldonic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0052648 ! ribitol phosphate metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: ai +creation_date: 2010-09-22T04:11:38Z + +[Term] +id: GO:0052646 +name: alditol phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group." [PMID:30240188] +synonym: "alditol phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: ai +creation_date: 2010-09-22T04:24:21Z + +[Term] +id: GO:0052647 +name: pentitol phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule." [ISBN:0198506732] +synonym: "pentitol phosphate metabolism" EXACT [] +is_a: GO:0052646 ! alditol phosphate metabolic process +created_by: ai +creation_date: 2010-09-22T04:26:28Z + +[Term] +id: GO:0052648 +name: ribitol phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose." [ISBN:0198506732] +synonym: "ribitol phosphate metabolism" EXACT [] +is_a: GO:0052647 ! pentitol phosphate metabolic process +created_by: ai +creation_date: 2010-09-22T04:28:37Z + +[Term] +id: GO:0052649 +name: coenzyme gamma-F420-2 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid." [GOC:curators] +synonym: "coenzyme F420 metabolic process" EXACT [CHEBI:16848] +synonym: "coenzyme F420 metabolism" EXACT [CHEBI:16848] +synonym: "coenzyme gamma-F420-2 metabolism" EXACT [] +synonym: "F420-2 metabolic process" EXACT [CHEBI:16848] +synonym: "F420-2 metabolism" EXACT [CHEBI:16848] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0052648 ! ribitol phosphate metabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: ai +creation_date: 2010-09-22T04:32:35Z + +[Term] +id: GO:0052650 +name: NADP-retinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+." [RHEA:25033] +synonym: "all-trans retinal reductase activity" BROAD [EC:1.1.1.300] +synonym: "all-trans-retinol dehydrogenase activity" BROAD [EC:1.1.1.300] +synonym: "NADP(H)-dependent retinol dehydrogenase/reductase activity" EXACT [EC:1.1.1.300] +synonym: "retinol dehydrogenase [NADP+] activity" EXACT [EC:1.1.1.300] +synonym: "retinol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.300] +xref: EC:1.1.1.300 +xref: KEGG_REACTION:R08379 +xref: MetaCyc:RXN-10841 +xref: Reactome:R-HSA-2464803 "RDH8 reduces atRAL to atROL" +xref: Reactome:R-HSA-2464822 "RDH12 reduces atRAL to atROL" +xref: Reactome:R-HSA-2465921 "11cRDH oxidises 11cROL to 11cRAL" +xref: Reactome:R-HSA-2465940 "atRAL is reduced to atROL" +xref: Reactome:R-HSA-2466861 "Defective RDH12 does not reduce atRAL to atROL and causes LCA13" +xref: Reactome:R-HSA-2471670 "Defective RDH12 does not reduce atRAL to atROL" +xref: Reactome:R-HSA-5419165 "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL" +xref: Reactome:R-HSA-5615668 "AKR1C3 reduces atRAL to atROL" +xref: Reactome:R-HSA-5623643 "RDH13 reduces atRAL to atROL" +xref: Reactome:R-HSA-74872 "RDH10,11 oxidise 11cROL to 11cRAL" +xref: RHEA:25033 +is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0052651 +name: monoacylglycerol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified." [PMID:25290914] +synonym: "monoacylglycerol breakdown" EXACT [] +synonym: "monoacylglycerol catabolism" EXACT [] +synonym: "monoacylglycerol degradation" EXACT [] +is_a: GO:0046462 ! monoacylglycerol metabolic process +is_a: GO:0046464 ! acylglycerol catabolic process +creation_date: 2010-09-23T09:26:36Z + +[Term] +id: GO:0052652 +name: cyclic purine nucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine." [PMID:23911318] +synonym: "cyclic purine nucleotide metabolism" EXACT [] +is_a: GO:0006164 ! purine nucleotide biosynthetic process +is_a: GO:0009190 ! cyclic nucleotide biosynthetic process +creation_date: 2010-09-23T11:15:59Z + +[Term] +id: GO:0052653 +name: 3',5'-cyclic diguanylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine." [GOC:curators] +synonym: "3',5'-cyclic diguanylic acid metabolism" EXACT [] +synonym: "cdiGMP metabolic process" EXACT [] +synonym: "cdiGMP metabolism" EXACT [] +synonym: "cyclic diguanylate metabolic process" EXACT [] +synonym: "cyclic diguanylate metabolism" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0052652 ! cyclic purine nucleotide metabolic process +created_by: ai +creation_date: 2010-09-23T11:16:56Z + +[Term] +id: GO:0052654 +name: L-leucine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN] +subset: goslim_chembl +synonym: "L-leucine aminotransferase activity" EXACT [] +xref: EC:2.6.1.42 +xref: KEGG_REACTION:R01090 +xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN +is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity + +[Term] +id: GO:0052655 +name: L-valine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN] +subset: goslim_chembl +synonym: "L-valine aminotransferase activity" EXACT [] +xref: EC:2.6.1.42 +xref: KEGG_REACTION:R01214 +xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN +is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity + +[Term] +id: GO:0052656 +name: L-isoleucine transaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid." [EC:2.6.1.42, MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN] +subset: goslim_chembl +synonym: "L-isoleucine aminotransferase activity" EXACT [] +xref: EC:2.6.1.42 +xref: KEGG_REACTION:R02199 +xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN +is_a: GO:0004084 ! branched-chain-amino-acid transaminase activity + +[Term] +id: GO:0052657 +name: guanine phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.8, GOC:curators] +synonym: "6-hydroxypurine phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "6-mercaptopurine phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "GMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "GPRT" RELATED [EC:2.4.2.8] +synonym: "guanine-hypoxanthine phosphoribosyltransferase activity" BROAD [EC:2.4.2.8] +synonym: "guanosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "guanosine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] +synonym: "guanylate pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "guanylic pyrophosphorylase activity" EXACT [EC:2.4.2.8] +synonym: "hypoxanthine-guanine phosphoribosyltransferase activity" BROAD [EC:2.4.2.8] +synonym: "purine-6-thiol phosphoribosyltransferase activity" RELATED [EC:2.4.2.8] +synonym: "Transphosphoribosidase activity" BROAD [EC:2.4.2.8] +xref: EC:2.4.2.8 +xref: KEGG_REACTION:R01229 +xref: MetaCyc:GUANPRIBOSYLTRAN-RXN +is_a: GO:0106130 ! purine phosphoribosyltransferase activity + +[Term] +id: GO:0052658 +name: inositol-1,4,5-trisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate." [EC:3.1.3.56, RHEA:19797] +synonym: "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.56] +synonym: "5PTase activity" RELATED [EC:3.1.3.56] +synonym: "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "inosine triphosphatase activity" RELATED [EC:3.1.3.56] +synonym: "inositol 1,4,5-trisphosphate phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "inositol phosphate 5-phosphomonoesterase activity" BROAD [EC:3.1.3.56] +synonym: "inositol polyphosphate-5-phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "inositol triphosphate 5-phosphomonoesterase activity" BROAD [] +synonym: "inositol trisphosphate phosphomonoesterase activity" BROAD [EC:3.1.3.56] +synonym: "Ins(1,4,5)P3 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "InsP(3) 5-phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "InsP3 5-phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity" BROAD [EC:3.1.3.56] +synonym: "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "type I inositol-polyphosphate phosphatase activity" RELATED [EC:3.1.3.56] +synonym: "type II inositol polyphosphate 5-phosphatase activity" RELATED [] +xref: EC:3.1.3.56 +xref: KEGG_REACTION:R03394 +xref: MetaCyc:3.1.3.56-RXN +xref: Reactome:R-HSA-1855174 "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol" +xref: Reactome:R-HSA-1855222 "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane" +xref: RHEA:19797 +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity + +[Term] +id: GO:0052659 +name: inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [EC:3.1.3.56, RHEA:11392] +synonym: "5PTase activity" RELATED [EC:3.1.3.56] +synonym: "D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "inositol polyphosphate-5-phosphatase activity" BROAD [EC:3.1.3.56] +synonym: "Ins(1,3,4,5)P(4) 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "Ins(1,3,4,5)P4 5-phosphatase activity" EXACT [EC:3.1.3.56] +synonym: "type I inositol-polyphosphate phosphatase activity" RELATED [EC:3.1.3.56] +synonym: "type II inositol polyphosphate 5-phosphatase activity" RELATED [] +xref: EC:3.1.3.56 +xref: KEGG_REACTION:R03430 +xref: MetaCyc:RXN-8730 +xref: Reactome:R-HSA-1855213 "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane" +xref: Reactome:R-HSA-1855218 "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol" +xref: RHEA:11392 +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity + +[Term] +id: GO:0052660 +name: R-lactaldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+." [RHEA:23872] +synonym: "(R)-propane-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.77] +synonym: "D-lactaldehyde:propanediol oxidoreductase activity" EXACT [EC:1.1.1.77] +xref: KEGG_REACTION:R03080 +xref: MetaCyc:RXN-8641 +xref: RHEA:23872 +is_a: GO:0008912 ! lactaldehyde reductase activity + +[Term] +id: GO:0052661 +name: S-lactaldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+." [RHEA:15933] +synonym: "(S)-propane-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.77] +synonym: "L-lactaldehyde:propanediol oxidoreductase activity" EXACT [EC:1.1.1.77] +xref: KEGG_REACTION:R02258 +xref: MetaCyc:LACTALDREDUCT-RXN +xref: RHEA:15933 +is_a: GO:0008912 ! lactaldehyde reductase activity + +[Term] +id: GO:0052662 +name: zeaxanthin epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O." [EC:1.14.13.90, RHEA:24084] +synonym: "zea-epoxidase activity" EXACT [EC:1.14.13.90] +synonym: "zeaxanthin,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.13.90] +xref: EC:1.14.13.90 +xref: KEGG_REACTION:R06946 "zeaxanthin,NADH:oxygen oxidoreductase activity" +xref: KEGG_REACTION:R07199 "zeaxanthin,NADPH:oxygen oxidoreductase activity" +xref: MetaCyc:RXN-7978 +xref: RHEA:24084 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052663 +name: antheraxanthin epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: antheraxanthin + NAD(P)H + H+ + O2 = all-trans-violaxanthin + NAD(P)+ + H2O." [MetaCyc:RXN-7979] +synonym: "antheraxanthin,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.13.90] +xref: EC:1.14.13.90 +xref: KEGG_REACTION:R06947 "antheraxanthin,NADH:oxygen oxidoreductase activity" +xref: KEGG_REACTION:R07200 "antheraxanthin,NADPH:oxygen oxidoreductase activity" +xref: MetaCyc:RXN-7979 +xref: RHEA:14937 +xref: RHEA:14944 "antheraxanthin,NADH:oxygen oxidoreductase activity" +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052664 +name: nitroalkane oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2." [EC:1.7.3.1] +synonym: "NAO activity" EXACT [EC:1.7.3.1] +synonym: "nitroalkane reductase activity" EXACT [EC:1.7.3.1] +synonym: "nitroalkane:oxygen oxidoreductase activity" EXACT [EC:1.7.3.1] +xref: EC:1.7.3.1 +xref: KEGG_REACTION:R00799 +xref: MetaCyc:RXN-11045 +is_a: GO:0016663 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor +creation_date: 2010-10-11T10:50:59Z + +[Term] +id: GO:0052665 +name: tRNA (uracil-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil." [EC:2.1.1.34] +synonym: "S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "transfer ribonucleate uracil 2'-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA (uracil 2')-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA uracil 2'-methyltransferase activity" EXACT [EC:2.1.1.34] +synonym: "tRNA uracil-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] +xref: MetaCyc:RXN0-5143 +xref: Reactome:R-HSA-6788707 "TRMT44 2'-O-methylates uridine-44 in tRNA(Ser)" +is_a: GO:0016300 ! tRNA (uracil) methyltransferase activity +is_a: GO:0106050 ! tRNA 2'-O-methyltransferase activity +created_by: ai +creation_date: 2010-10-11T01:05:35Z + +[Term] +id: GO:0052666 +name: tRNA (cytosine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine." [GOC:hjd] +synonym: "S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity" EXACT [] +synonym: "transfer ribonucleate cytosine 2'-methyltransferase activity" EXACT [] +synonym: "tRNA (cytosine 2')-methyltransferase activity" EXACT [] +synonym: "tRNA cytosine 2'-methyltransferase activity" EXACT [] +synonym: "tRNA cytosine-2'-O-methyltransferase activity" EXACT [] +xref: MetaCyc:RXN0-5143 +xref: Reactome:R-HSA-6788668 "TRMT13 2'-O-methylates adenosine-4 in tRNA" +xref: Reactome:R-HSA-6788684 "TRMT13 2'-O-methylates cytidine-4 in tRNA" +xref: Reactome:R-HSA-9024159 "FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe)" +is_a: GO:0016427 ! tRNA (cytosine) methyltransferase activity +created_by: ai +creation_date: 2010-10-11T01:05:47Z + +[Term] +id: GO:0052667 +name: phosphomethylethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)." [KEGG_REACTION:R06868, MetaCyc:RXN-5642, RHEA:25322] +synonym: "N-methylethanolamine phosphate N-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity" EXACT systematic_synonym [KEGG_REACTION:R06868] +xref: KEGG_REACTION:R06868 +xref: MetaCyc:RXN-5642 +xref: RHEA:25322 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: ai +creation_date: 2011-04-11T11:36:47Z + +[Term] +id: GO:0052668 +name: farnesol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: farnesol + nucleoside triphosphate = farnesyl monophosphate + nucleoside diphosphate." [GOC:kd, MetaCyc:RXN-11625] +synonym: "farnesol phosphotransferase activity" EXACT [] +synonym: "trans,trans-farnesol kinase activity" NARROW [] +xref: EC:2.7.1.216 +is_a: GO:0052673 ! prenol kinase activity +created_by: ai +creation_date: 2011-04-11T01:19:25Z + +[Term] +id: GO:0052669 +name: CTP:2-trans,-6-trans-farnesol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+." [MetaCyc:RXN-11625] +synonym: "CTP:2-trans,-6-trans-farnesol phosphotransferase activity" EXACT [] +xref: EC:2.7.1.216 +xref: MetaCyc:RXN-11625 +is_a: GO:0052668 ! farnesol kinase activity +created_by: ai +creation_date: 2011-04-11T01:32:05Z + +[Term] +id: GO:0052670 +name: geraniol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate." [GOC:kd] +synonym: "geraniol phosphotransferase activity" EXACT [] +is_a: GO:0052673 ! prenol kinase activity +created_by: ai +creation_date: 2011-04-11T03:14:02Z + +[Term] +id: GO:0052671 +name: geranylgeraniol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate." [GOC:kd, MetaCyc:RXN-11629] +synonym: "geranylgeraniol phosphotransferase activity" EXACT [] +xref: EC:2.7.1.B19 +is_a: GO:0052673 ! prenol kinase activity +created_by: ai +creation_date: 2011-04-11T03:18:44Z + +[Term] +id: GO:0052672 +name: CTP:geranylgeraniol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP." [MetaCyc:RXN-11629] +synonym: "CTP:geranylgeraniol phosphotransferase activity" EXACT [] +xref: EC:2.7.1.216 +xref: MetaCyc:RXN-11629 +is_a: GO:0052671 ! geranylgeraniol kinase activity +created_by: ai +creation_date: 2011-04-11T03:26:04Z + +[Term] +id: GO:0052673 +name: prenol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity." [GOC:ai, GOC:kd] +synonym: "prenol phosphotransferase activity" EXACT [] +synonym: "prenyl alcohol kinase activity" EXACT [] +synonym: "prenyl alcohol phosphotransferase activity" EXACT [] +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +created_by: ai +creation_date: 2011-04-11T04:02:23Z + +[Term] +id: GO:0052674 +name: ent-pimara-9(11),15-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate." [RHEA:25544] +synonym: "ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity" EXACT systematic_synonym [EC:4.2.3.31] +synonym: "PMD synthase activity" BROAD [EC:4.2.3.31] +xref: EC:4.2.3.31 +xref: MetaCyc:RXN-9299 +xref: RHEA:25544 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052675 +name: 3-methylbutanol:NADP oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde." [EC:1.1.1.265, KEGG_REACTION:R05686] +synonym: "3-methylbutanal reductase (NADP) activity" EXACT [] +synonym: "3-methylbutanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.265] +synonym: "3-methylbutyraldehyde reductase (NADP) activity" EXACT [] +synonym: "isoamyl alcohol oxidase (NADP) activity" EXACT [] +xref: KEGG_REACTION:R05686 +xref: RHEA:18525 +is_a: GO:0008106 ! alcohol dehydrogenase (NADP+) activity +created_by: ai +creation_date: 2011-04-12T11:19:27Z + +[Term] +id: GO:0052676 +name: 3-methylbutanol:NAD oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde." [EC:1.1.1.265, KEGG_REACTION:R05685] +synonym: "3-methylbutanal reductase (NAD) activity" EXACT [] +synonym: "3-methylbutanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.265] +synonym: "3-methylbutyraldehyde reductase (NAD) activity" EXACT [] +synonym: "isoamyl alcohol oxidase (NAD) activity" EXACT [] +xref: KEGG_REACTION:R05685 +xref: RHEA:18529 +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity +created_by: ai +creation_date: 2011-04-12T11:22:42Z + +[Term] +id: GO:0052677 +name: D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+." [EC:1.1.1.287] +synonym: "ARD1p" RELATED [EC:1.1.1.287] +synonym: "D-arabinitol dehydrogenase 1 activity" BROAD [EC:1.1.1.287] +synonym: "D-arabinitol:NADP+ dehydrogenase activity" BROAD [EC:1.1.1.287] +synonym: "NADP+-dependent D-arabinitol dehydrogenase activity" BROAD [EC:1.1.1.287] +xref: KEGG_REACTION:R07143 +xref: MetaCyc:RXN-7971 +xref: RHEA:21276 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-04-12T02:33:43Z + +[Term] +id: GO:0052678 +name: levopimaradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate." [RHEA:25548] +synonym: "ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity" EXACT systematic_synonym [EC:4.2.3.32] +xref: EC:4.2.3.32 +xref: KEGG_REACTION:R06302 +xref: MetaCyc:4.2.3.32-RXN +xref: RHEA:25548 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052679 +name: terpentetriene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene." [RHEA:25617] +synonym: "terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity" EXACT systematic_synonym [EC:4.2.3.36] +xref: EC:4.2.3.36 +xref: MetaCyc:RXN-9455 +xref: RHEA:25617 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052680 +name: epi-isozizaene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate." [RHEA:25992] +synonym: "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity" EXACT systematic_synonym [EC:4.2.3.37, KEGG_REACTION:R07830] +xref: EC:4.2.3.37 +xref: KEGG_REACTION:R07830 +xref: MetaCyc:RXN-9349 +xref: RHEA:25992 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052681 +name: alpha-bisabolene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate." [RHEA:25436] +synonym: "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity" EXACT systematic_synonym [EC:4.2.3.38] +synonym: "bisabolene synthase activity" BROAD [KEGG_REACTION:R08370] +xref: EC:4.2.3.38 +xref: KEGG_REACTION:R08370 +xref: MetaCyc:RXN-8550 +xref: RHEA:25436 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052682 +name: epi-cedrol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate." [RHEA:26115] +synonym: "(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity" EXACT systematic_synonym [EC:4.2.3.39] +synonym: "8-epicedrol synthase activity" EXACT [] +synonym: "epicedrol synthase activity" EXACT [] +xref: EC:4.2.3.39 +xref: KEGG_REACTION:R09140 +xref: MetaCyc:RXN-10004 +xref: RHEA:26115 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052683 +name: (Z)-gamma-bisabolene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate." [RHEA:26081] +synonym: "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity" EXACT systematic_synonym [EC:4.2.3.40] +xref: EC:4.2.3.40 +xref: MetaCyc:RXN-10005 +xref: RHEA:26081 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0052684 +name: L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O." [MetaCyc:RXN0-2382] +synonym: "L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity" EXACT [GOC:bf] +synonym: "tryptophan synthase beta subunit activity" NARROW [] +xref: EC:4.2.1.122 +xref: KEGG_REACTION:R00674 +xref: MetaCyc:RXN0-2382 +xref: RHEA:26434 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0052685 +name: perillic acid:CoA ligase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA." [KEGG_REACTION:R06368] +synonym: "perillyl-CoA synthetase activity" BROAD [UM-BBD_reactionID:r0731] +xref: EC:6.2.1 +xref: KEGG_REACTION:R06367 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0052686 +name: perillic acid:CoA ligase (AMP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA." [KEGG_REACTION:R06368] +synonym: "perillyl-CoA synthetase activity" BROAD [UM-BBD_reactionID:r0731] +xref: KEGG_REACTION:R06368 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0052687 +name: (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [KEGG_REACTION:R06396] +synonym: "3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity" BROAD [UM-BBD_reactionID:r0737] +xref: KEGG_REACTION:R06396 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0052688 +name: (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [KEGG_REACTION:R06515] +synonym: "3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity" BROAD [UM-BBD_reactionID:r0737] +xref: KEGG_REACTION:R06515 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0052689 +name: carboxylic ester hydrolase activity +namespace: molecular_function +alt_id: GO:0004091 +alt_id: GO:0004302 +alt_id: GO:0004759 +alt_id: GO:0016789 +def: "Catalysis of the hydrolysis of a carboxylic ester bond." [EC:3.1.1, EC:3.1.1.1, GOC:curators] +subset: goslim_drosophila +synonym: "ali-esterase activity" NARROW [EC:3.1.1.1] +synonym: "alpha-carboxylesterase activity" NARROW [EC:3.1.1.1] +synonym: "B-esterase activity" RELATED [EC:3.1.1.1] +synonym: "carboxyesterase activity" EXACT [EC:3.1.1.1] +synonym: "carboxyl ester hydrolase activity" EXACT [EC:3.1.1.1] +synonym: "carboxylate esterase activity" EXACT [EC:3.1.1.1] +synonym: "carboxylesterase activity" EXACT [] +synonym: "carboxylic acid esterase activity" EXACT [] +synonym: "carboxylic ester hydrolase activity" RELATED [] +synonym: "carboxylic esterase activity" EXACT [EC:3.1.1.1] +synonym: "cocaine esterase activity" NARROW [EC:3.1.1.1] +synonym: "esterase A" NARROW [EC:3.1.1.1] +synonym: "esterase B" NARROW [EC:3.1.1.1] +synonym: "nonspecific carboxylesterase activity" RELATED [EC:3.1.1.1] +synonym: "procaine esterase activity" NARROW [EC:3.1.1.1] +synonym: "serine esterase activity" NARROW [] +synonym: "triacetin esterase" NARROW [EC:3.1.1.1] +synonym: "vitamin A esterase" NARROW [EC:3.1.1.1] +xref: EC:3.1.1 +xref: EC:3.1.1.1 +xref: KEGG_REACTION:R00630 +xref: MetaCyc:CARBOXYLESTERASE-RXN +xref: Reactome:R-HSA-5693691 "CES1 trimer.CES2 hydrolyse COCN to BEG" +xref: Reactome:R-HSA-8937442 "CES3 hydrolyses CHEST to CHOL and LCFA(-)" +xref: Reactome:R-HSA-9619024 "CES1trimer hydrolyses ACEI pro-drugs to ACEIs" +xref: UM-BBD_reactionID:r1025 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0052690 +name: trichloro-p-hydroquinone reductive dehalogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl." [UM-BBD_reactionID:r0031, UM-BBD_reactionID:r0315] +synonym: "pentaerythritol tetranitrate reductase activity" RELATED [UM-BBD_enzymeID:e0028] +synonym: "tetrachlorohydroquinone reductive dehalogenase activity" RELATED [UM-BBD_enzymeID:e0251] +synonym: "trichlorohydroquinone reductive dehalogenase activity" EXACT [] +synonym: "xenobiotic reductase activity" BROAD [UM-BBD_enzymeID:e0028] +xref: EC:1.6.99.1 +xref: EC:1.8.99 +xref: UM-BBD_reactionID:r0031 +xref: UM-BBD_reactionID:r0315 +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0052691 +name: UDP-arabinopyranose mutase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose." [EC:5.4.99.30, RHEA:28350] +synonym: "UDP-arabinopyranose pyranomutase activity" EXACT systematic_synonym [EC:5.4.99.30] +synonym: "UDP-L-Ara mutase activity" EXACT [EC:5.4.99.30] +synonym: "UDP-L-arabinopyranose furanomutase activity" EXACT [EC:5.4.99.30] +synonym: "UDP-L-arabinose mutase activity" EXACT [EC:5.4.99.30] +synonym: "uridine-diphosphate-L-arabinose mutase activity" EXACT [EC:5.4.99.30] +xref: EC:5.4.99.30 +xref: MetaCyc:RXN-11552 +xref: RHEA:28350 +is_a: GO:0016866 ! intramolecular transferase activity + +[Term] +id: GO:0052692 +name: raffinose alpha-galactosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose." [MetaCyc:RXN-11502] +synonym: "alkaline alpha-galactosidase activity" BROAD [] +synonym: "raffinose galactohydrolase activity" BROAD [] +synonym: "raffinose-specific alkaline alpha-galactosidase activity" EXACT [PMID:20739305] +xref: EC:3.2.1.22 +xref: KEGG_REACTION:R01103 +xref: MetaCyc:RXN-11502 +is_a: GO:0004557 ! alpha-galactosidase activity + +[Term] +id: GO:0052693 +name: epoxyqueuosine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant." [PMID:21502530, RHEA:32159] +xref: EC:1.17.99.6 +xref: RHEA:32159 +is_a: GO:0016491 ! oxidoreductase activity + +[Term] +id: GO:0052694 +name: jasmonoyl-isoleucine-12-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O." [MetaCyc:RXN-12421, PMID:21576464] +xref: MetaCyc:RXN-12421 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0052695 +name: cellular glucuronidation +namespace: biological_process +def: "The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor." [GOC:BHF] +synonym: "cellular glucuronide biosynthesis" EXACT [] +synonym: "cellular glucuronide biosynthetic process" EXACT [] +synonym: "cellular glucuronoside biosynthesis" EXACT [] +synonym: "cellular glucuronoside biosynthetic process" EXACT [] +is_a: GO:0019585 ! glucuronate metabolic process +creation_date: 2011-07-27T05:28:18Z + +[Term] +id: GO:0052696 +name: flavonoid glucuronidation +namespace: biological_process +def: "The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor." [GOC:BHF, PMID:20056724] +synonym: "flavonoid glucuronide biosynthesis" EXACT [] +synonym: "flavonoid glucuronide biosynthetic process" EXACT [] +synonym: "flavonoid glucuronoside biosynthesis" EXACT [] +synonym: "flavonoid glucuronoside biosynthetic process" EXACT [] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:0052695 ! cellular glucuronidation +created_by: ai +creation_date: 2011-07-27T05:37:44Z + +[Term] +id: GO:0052697 +name: xenobiotic glucuronidation +namespace: biological_process +def: "The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion." [GOC:BHF, PMID:20056724] +synonym: "phase II metabolism" NARROW [] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0052695 ! cellular glucuronidation +created_by: ai +creation_date: 2011-07-27T05:37:50Z + +[Term] +id: GO:0052698 +name: ergothioneine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [Wikipedia:Ergothioneine] +synonym: "(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate metabolic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine metabolic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine metabolism" EXACT [CHEBI:4828] +synonym: "ergothioneine metabolism" EXACT [] +is_a: GO:0000096 ! sulfur amino acid metabolic process +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: ai +creation_date: 2011-08-01T03:52:11Z + +[Term] +id: GO:0052699 +name: ergothioneine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [Wikipedia:Ergothioneine] +synonym: "(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate biosynthetic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine anabolism" EXACT [] +synonym: "2-mercaptoergothioneine trimethylbetaine biosynthesis" EXACT [] +synonym: "2-mercaptoergothioneine trimethylbetaine biosynthetic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine formation" EXACT [] +synonym: "2-mercaptoergothioneine trimethylbetaine synthesis" EXACT [] +synonym: "ergothioneine anabolism" EXACT [] +synonym: "ergothioneine biosynthesis" EXACT [] +synonym: "ergothioneine formation" EXACT [] +synonym: "ergothioneine synthesis" EXACT [] +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0052698 ! ergothioneine metabolic process +is_a: GO:0052703 ! cellular modified histidine biosynthetic process +created_by: ai +creation_date: 2011-08-01T03:56:19Z + +[Term] +id: GO:0052700 +name: ergothioneine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties." [Wikipedia:Ergothioneine] +synonym: "(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate catabolic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine breakdown" EXACT [] +synonym: "2-mercaptoergothioneine trimethylbetaine catabolic process" EXACT [CHEBI:4828] +synonym: "2-mercaptoergothioneine trimethylbetaine catabolism" EXACT [] +synonym: "2-mercaptoergothioneine trimethylbetaine degradation" EXACT [] +synonym: "ergothioneine breakdown" EXACT [] +synonym: "ergothioneine catabolism" EXACT [] +synonym: "ergothioneine degradation" EXACT [] +is_a: GO:0000098 ! sulfur amino acid catabolic process +is_a: GO:0006579 ! amino-acid betaine catabolic process +is_a: GO:0052698 ! ergothioneine metabolic process +is_a: GO:0052702 ! cellular modified histidine catabolic process +created_by: ai +creation_date: 2011-08-01T03:56:22Z + +[Term] +id: GO:0052701 +name: cellular modified histidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai] +synonym: "cellular histidine derivative metabolic process" EXACT [] +synonym: "cellular histidine derivative metabolism" EXACT [] +synonym: "cellular modified histidine metabolism" EXACT [] +synonym: "histidine derivative metabolic process" EXACT [] +synonym: "modified histidine metabolic process" EXACT [] +synonym: "modified histidine metabolism" EXACT [] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +creation_date: 2011-08-01T03:47:00Z + +[Term] +id: GO:0052702 +name: cellular modified histidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai] +synonym: "cellular histidine derivative breakdown" EXACT [] +synonym: "cellular histidine derivative catabolic process" EXACT [] +synonym: "cellular histidine derivative catabolism" EXACT [] +synonym: "cellular histidine derivative degradation" EXACT [] +synonym: "cellular modified histidine breakdown" EXACT [] +synonym: "cellular modified histidine catabolism" EXACT [] +synonym: "cellular modified histidine degradation" EXACT [] +synonym: "histidine derivative catabolic process" EXACT [] +synonym: "modified histidine catabolic process" EXACT [] +synonym: "modified histidine catabolism" EXACT [] +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: ai +creation_date: 2011-08-01T03:48:41Z + +[Term] +id: GO:0052703 +name: cellular modified histidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai] +synonym: "cellular histidine derivative anabolism" EXACT [] +synonym: "cellular histidine derivative biosynthesis" EXACT [] +synonym: "cellular histidine derivative biosynthetic process" EXACT [] +synonym: "cellular histidine derivative formation" EXACT [] +synonym: "cellular histidine derivative synthesis" EXACT [] +synonym: "cellular modified histidine anabolism" EXACT [] +synonym: "cellular modified histidine biosynthesis" EXACT [] +synonym: "cellular modified histidine formation" EXACT [] +synonym: "cellular modified histidine synthesis" EXACT [] +synonym: "histidine derivative biosynthetic process" EXACT [] +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: ai +creation_date: 2011-08-01T03:49:39Z + +[Term] +id: GO:0052704 +name: ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine +namespace: biological_process +def: "The pathway resulting in the formation of ergothioneine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). N-alpha,N-alpha,N-alpha-trimethyl-L-histidine is modified by the ligation of gamma-glutamyl-cysteine and oxygen; this intermediate undergoes further modification by the removal of glutamate to produce hercynylcysteine sulfoxide. Finally, a beta-lyase acts on this compound, removing pyruvate, ammonia and oxygen to produce ergothioneine." [DOI:10.1021/ja101721e, EC:2.1.1.44, PMID:4276459, PMID:5484456, Wikipedia:Ergothioneine] +is_a: GO:0006548 ! histidine catabolic process +is_a: GO:0052699 ! ergothioneine biosynthetic process +is_a: GO:0052708 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process +relationship: has_part GO:0052707 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine +relationship: has_part GO:0052711 ! ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine +creation_date: 2011-08-05T11:31:52Z + +[Term] +id: GO:0052705 +name: methylhistidine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine." [EC:2.1.1.44] +synonym: "histidine-alpha-N-methyltransferase activity" BROAD [EC:2.1.1.44] +synonym: "methylhistidine methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity" EXACT [EC:2.1.1.44] +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: ai +creation_date: 2011-08-05T11:54:54Z + +[Term] +id: GO:0052706 +name: histidine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine." [EC:2.1.1.44] +synonym: "histidine methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "histidine-alpha-N-methyltransferase activity" BROAD [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity" EXACT [EC:2.1.1.44] +synonym: "S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity" EXACT [EC:2.1.1.44] +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: ai +creation_date: 2011-08-05T11:57:40Z + +[Term] +id: GO:0052707 +name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine +namespace: biological_process +def: "The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)." [EC:2.1.1.44] +synonym: "hercynine biosynthesis from histidine" EXACT [] +synonym: "histidine betaine biosynthesis from histidine" EXACT [] +synonym: "histidine catabolic process to hercynine" EXACT [] +synonym: "histidine catabolism to hercynine" EXACT [] +synonym: "histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine" EXACT [] +xref: KEGG_REACTION:R01169 +is_a: GO:0006548 ! histidine catabolic process +is_a: GO:0052709 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process +relationship: has_part GO:0030745 ! dimethylhistidine N-methyltransferase activity +relationship: has_part GO:0052705 ! methylhistidine N-methyltransferase activity +relationship: has_part GO:0052706 ! histidine N-methyltransferase activity +created_by: ai +creation_date: 2011-08-05T02:07:24Z + +[Term] +id: GO:0052708 +name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [GOC:curators] +synonym: "hercynine metabolic process" EXACT [CHEBI:15781] +synonym: "hercynine metabolism" EXACT [CHEBI:15781] +synonym: "histidine betaine metabolic process" EXACT [CHEBI:15781] +synonym: "histidine betaine metabolism" EXACT [CHEBI:15781] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolism" EXACT [] +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: ai +creation_date: 2011-08-05T02:13:31Z + +[Term] +id: GO:0052709 +name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [GOC:curators] +synonym: "hercynine anabolism" EXACT [] +synonym: "hercynine biosynthesis" EXACT [] +synonym: "hercynine biosynthetic process" EXACT [] +synonym: "hercynine formation" EXACT [] +synonym: "hercynine synthesis" EXACT [] +synonym: "histidine betaine anabolism" EXACT [] +synonym: "histidine betaine biosynthesis" EXACT [] +synonym: "histidine betaine biosynthetic process" EXACT [] +synonym: "histidine betaine formation" EXACT [] +synonym: "histidine betaine synthesis" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine anabolism" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine formation" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine synthesis" EXACT [] +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0052708 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +created_by: ai +creation_date: 2011-08-05T02:22:05Z + +[Term] +id: GO:0052710 +name: N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine." [GOC:curators] +synonym: "hercynine breakdown" EXACT [] +synonym: "hercynine catabolic process" EXACT [] +synonym: "hercynine catabolism" EXACT [] +synonym: "hercynine degradation" EXACT [] +synonym: "histidine betaine breakdown" EXACT [] +synonym: "histidine betaine catabolic process" EXACT [] +synonym: "histidine betaine catabolism" EXACT [] +synonym: "histidine betaine degradation" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine breakdown" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine degradation" EXACT [] +is_a: GO:0006579 ! amino-acid betaine catabolic process +is_a: GO:0052708 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +created_by: ai +creation_date: 2011-08-05T02:22:54Z + +[Term] +id: GO:0052711 +name: ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine +namespace: biological_process +def: "The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)." [KEGG_REACTION:R04878] +synonym: "ergothioneine biosynthesis from hercynine" EXACT [] +synonym: "ergothioneine biosynthesis from histidine betaine" EXACT [] +synonym: "hercynine catabolism to ergothioneine" EXACT [] +synonym: "histidine betaine catabolism to ergothioneine" EXACT [] +synonym: "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine" EXACT [] +xref: KEGG_REACTION:R04878 +is_a: GO:0052699 ! ergothioneine biosynthetic process +is_a: GO:0052710 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process +creation_date: 2011-08-05T04:06:16Z + +[Term] +id: GO:0052712 +name: inositol phosphosphingolipid phospholipase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol." [GOC:ai] +is_a: GO:0004629 ! phospholipase C activity +created_by: ai +creation_date: 2011-08-05T04:49:13Z + +[Term] +id: GO:0052713 +name: inositol phosphorylceramide phospholipase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol." [GOC:ai] +is_a: GO:0052712 ! inositol phosphosphingolipid phospholipase activity +created_by: ai +creation_date: 2011-08-05T04:51:03Z + +[Term] +id: GO:0052714 +name: mannosyl-inositol phosphorylceramide phospholipase activity +namespace: molecular_function +def: "Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol." [GOC:ai] +is_a: GO:0052713 ! inositol phosphorylceramide phospholipase activity +created_by: ai +creation_date: 2011-08-05T08:02:57Z + +[Term] +id: GO:0052715 +name: mannosyl-diinositol phosphorylceramide phospholipase activity +namespace: molecular_function +def: "Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol." [GOC:ai] +is_a: GO:0052713 ! inositol phosphorylceramide phospholipase activity +created_by: ai +creation_date: 2011-08-05T08:02:57Z + +[Term] +id: GO:0052716 +name: hydroquinone:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O." [EC:1.10.3.2] +synonym: "benzenediol:oxygen oxidoreductase activity" BROAD [] +synonym: "laccase reaction" BROAD [] +synonym: "p-diphenol:oxygen oxidoreductase activity" EXACT [] +xref: EC:1.10.3.2 +xref: KEGG_REACTION:R00083 +xref: MetaCyc:LACCASE-RXN +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor +created_by: ai +creation_date: 2011-08-11T03:18:19Z + +[Term] +id: GO:0052717 +name: tRNA-specific adenosine-34 deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule." [PMID:17875641] +synonym: "tRNA(Ala)-A34 deaminase activity" EXACT [] +is_a: GO:0008251 ! tRNA-specific adenosine deaminase activity +created_by: ai +creation_date: 2011-08-12T11:48:54Z + +[Term] +id: GO:0052718 +name: tRNA-specific adenosine-34 deaminase complex +namespace: cellular_component +def: "A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human." [PMID:17875641] +synonym: "tRNA-A34 deaminase complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular +created_by: ai +creation_date: 2011-08-12T11:53:26Z + +[Term] +id: GO:0052719 +name: apurinic/apyrimidinic endoribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends." [PMID:19401441] +synonym: "abasic endoribonuclease activity" EXACT [] +synonym: "AP endoribonuclease activity" EXACT [] +synonym: "apurinic endoribonuclease activity" NARROW [] +synonym: "apyrimidinic endoribonuclease activity" NARROW [] +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0052720 +name: class II DNA-(apurinic or apyrimidinic site) endonuclease activity +namespace: molecular_function +alt_id: GO:0140079 +def: "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends." [PMID:19401441] +comment: Class II AP endonuclease is a nuclease, but not Class I, III and IV. +synonym: "class II DNA-(apurinic or apyrimidinic site) lyase activity" EXACT [] +is_a: GO:0003906 ! DNA-(apurinic or apyrimidinic site) endonuclease activity +is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13409 xsd:anyURI +created_by: pg +creation_date: 2017-07-24T11:46:03Z + +[Term] +id: GO:0052721 +name: regulation of apurinic/apyrimidinic endodeoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends." [PMID:19401441] +synonym: "regulation of abasic endodeoxyribonuclease activity" EXACT [] +synonym: "regulation of AP endodeoxyribonuclease activity" EXACT [] +synonym: "regulation of apurinic endodeoxyribonuclease activity" NARROW [] +synonym: "regulation of apyrimidinic endodeoxyribonuclease activity" NARROW [] +is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity +relationship: regulates GO:0052720 ! class II DNA-(apurinic or apyrimidinic site) endonuclease activity + +[Term] +id: GO:0052722 +name: fatty acid in-chain hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O." [MetaCyc:RXN-12186] +xref: MetaCyc:RXN-12186 +is_a: GO:0004497 ! monooxygenase activity +created_by: ai +creation_date: 2011-08-15T01:41:07Z + +[Term] +id: GO:0052723 +name: inositol hexakisphosphate 1-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179] +xref: EC:2.7.4.21 +xref: KEGG_REACTION:R05799 +xref: MetaCyc:RXN-10972 +is_a: GO:0000828 ! inositol hexakisphosphate kinase activity +created_by: ai +creation_date: 2011-08-16T11:47:36Z + +[Term] +id: GO:0052724 +name: inositol hexakisphosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179] +xref: EC:2.7.4.21 +xref: MetaCyc:RXN-10971 +is_a: GO:0000828 ! inositol hexakisphosphate kinase activity +created_by: ai +creation_date: 2011-08-16T11:50:48Z + +[Term] +id: GO:0052725 +name: inositol-1,3,4-trisphosphate 6-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134] +synonym: "1D-myo-inositol-trisphosphate 6-kinase activity" BROAD [] +synonym: "ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.127] +synonym: "inositol 1,3,4-trisphosphate 6-kinase activity" EXACT [] +synonym: "inositol-trisphosphate 6-kinase activity" BROAD [] +synonym: "ins(1,3,4)P(3) 6-kinase activity" EXACT [EC:2.7.1.127] +synonym: "Ins(1,3,4)P3 6-kinase activity" EXACT [EC:2.7.1.127] +synonym: "IP3 6-kinase activity" BROAD [EC:2.7.1.127] +xref: EC:2.7.1.159 +xref: MetaCyc:2.7.1.133-RXN +xref: Reactome:R-HSA-1855197 "I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol" +xref: Reactome:R-HSA-2267372 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4" +is_a: GO:0051766 ! inositol trisphosphate kinase activity +created_by: ai +creation_date: 2011-08-16T12:42:59Z + +[Term] +id: GO:0052726 +name: inositol-1,3,4-trisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134] +synonym: "1D-myo-inositol-trisphosphate 5-kinase activity" BROAD [] +synonym: "ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.127] +synonym: "inositol 1,3,4-trisphosphate 5-kinase activity" EXACT [] +synonym: "inositol-trisphosphate 5-kinase activity" BROAD [] +synonym: "ins(1,3,4)P(3) 5-kinase activity" EXACT [EC:2.7.1.127] +synonym: "Ins(1,3,4)P3 5-kinase activity" EXACT [EC:2.7.1.127] +synonym: "IP3 5-kinase activity" BROAD [EC:2.7.1.127] +xref: EC:2.7.1.159 +xref: KEGG_REACTION:R03428 +xref: MetaCyc:2.7.1.139-RXN +xref: Reactome:R-HSA-1855172 "I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol" +xref: Reactome:R-HSA-994140 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4" +is_a: GO:0051766 ! inositol trisphosphate kinase activity +created_by: ai +creation_date: 2011-08-16T12:43:11Z + +[Term] +id: GO:0052727 +name: capsanthin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: antheraxanthin = capsanthin." [EC:5.3.99.8] +synonym: "capsanthin-capsorubin synthase activity" BROAD [EC:5.3.99.8] +synonym: "CCS" RELATED [EC:5.3.99.8] +synonym: "ketoxanthophyll synthase activity" BROAD [EC:5.3.99.8] +xref: EC:5.3.99.8 +xref: MetaCyc:RXN-7947 +is_a: GO:0016860 ! intramolecular oxidoreductase activity +created_by: ai +creation_date: 2011-08-16T03:09:21Z + +[Term] +id: GO:0052728 +name: capsorubin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: violaxanthin = capsorubin." [EC:5.3.99.8] +synonym: "capsanthin-capsorubin synthase activity" BROAD [EC:5.3.99.8] +synonym: "CCS" RELATED [EC:5.3.99.8] +synonym: "ketoxanthophyll synthase activity" BROAD [EC:5.3.99.8] +synonym: "violaxanthin-capsorubin isomerase (ketone-forming) activity" EXACT [EC:5.3.99.8] +xref: EC:5.3.99.8 +xref: MetaCyc:RXN-7946 +is_a: GO:0016860 ! intramolecular oxidoreductase activity +created_by: ai +creation_date: 2011-08-16T03:09:26Z + +[Term] +id: GO:0052729 +name: dimethylglycine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine." [EC:2.1.1.157] +synonym: "ApDMT" RELATED [EC:2.1.1.157] +synonym: "S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity" EXACT [EC:2.1.1.157] +xref: EC:2.1.1.157 +xref: EC:2.1.1.161 +xref: EC:2.1.1.162 +xref: KEGG_REACTION:R07244 +xref: MetaCyc:R482-RXN +xref: MetaCyc:RXN-9680 +xref: RHEA:10072 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: ai +creation_date: 2011-08-16T03:45:16Z + +[Term] +id: GO:0052730 +name: sarcosine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine." [EC:2.1.1.157] +synonym: "S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity" EXACT [EC:2.1.1.157] +synonym: "SDMT" RELATED [EC:2.1.1.157] +xref: EC:2.1.1.156 +xref: EC:2.1.1.157 +xref: EC:2.1.1.162 +xref: KEGG_REACTION:R07243 +xref: MetaCyc:R481-RXN +xref: MetaCyc:RXN-7042 +xref: MetaCyc:RXN-9679 +xref: RHEA:15453 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: ai +creation_date: 2011-08-16T03:45:39Z + +[Term] +id: GO:0052731 +name: phosphocholine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: choline phosphate + H2O = choline + phosphate." [EC:3.1.3.75] +synonym: "3X11A" RELATED [EC:3.1.3.75] +synonym: "PHOSPHO1" RELATED [EC:3.1.3.75] +synonym: "phosphoethanolamine phosphohydrolase activity" RELATED [EC:3.1.3.75] +xref: EC:3.1.3.75 +xref: KEGG_REACTION:R06871 +xref: MetaCyc:RXN-5647 +xref: Reactome:R-HSA-1483159 "PCho is dephosphorylated to Cho by PHOSPHO1" +xref: RHEA:10492 +is_a: GO:0016791 ! phosphatase activity +created_by: ai +creation_date: 2011-08-16T04:09:06Z + +[Term] +id: GO:0052732 +name: phosphoethanolamine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate." [EC:3.1.3.75] +synonym: "3X11A" RELATED [EC:3.1.3.75] +synonym: "PHOSPHO1" RELATED [EC:3.1.3.75] +synonym: "phosphoethanolamine phosphohydrolase activity" EXACT [EC:3.1.3.75] +xref: EC:3.1.3.75 +xref: KEGG_REACTION:R06870 +xref: MetaCyc:RXN-7948 +xref: Reactome:R-HSA-1483096 "PETA is dephosphorylated to ETA by PHOSPHO1" +xref: RHEA:16089 +is_a: GO:0016791 ! phosphatase activity +created_by: ai +creation_date: 2011-08-16T04:09:19Z + +[Term] +id: GO:0052733 +name: quinate 3-dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+." [RHEA:18425] +synonym: "quinate:NADP 3-oxidoreductase activity" EXACT [EC:1.1.1.24] +synonym: "quinate:NADP(+) 3-oxidoreductase activity" EXACT [EC:1.1.1.24] +synonym: "quinic dehydrogenase activity" BROAD [EC:1.1.1.24] +xref: EC:1.1.1.282 +xref: KEGG_REACTION:R06846 +xref: RHEA:18425 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-08-16T04:23:47Z + +[Term] +id: GO:0052734 +name: shikimate 3-dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+." [RHEA:17741] +synonym: "3-dehydroshikimate reductase activity" EXACT [EC:1.1.1.25] +synonym: "3-dehydroshikimic reductase activity" EXACT [EC:1.1.1.25] +synonym: "dehydroshikimic reductase activity" BROAD [EC:1.1.1.25] +synonym: "DHS reductase activity" BROAD [EC:1.1.1.25] +synonym: "shikimate oxidoreductase activity" BROAD [EC:1.1.1.25] +synonym: "shikimate:NAD(P)(+) 3-oxidoreductase activity" EXACT [EC:1.1.1.25] +synonym: "shikimate:NAD(P)(+) oxidoreductase activity" BROAD [EC:1.1.1.25] +xref: EC:1.1.1.282 +xref: KEGG_REACTION:R06847 +xref: RHEA:17741 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-08-16T04:28:23Z + +[Term] +id: GO:0052735 +name: tRNA (cytosine-3-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine." [PMID:21518804, PMID:21518805] +synonym: "S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity" EXACT [] +synonym: "S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity" EXACT [] +synonym: "transfer ribonucleate cytosine 3-methyltransferase activity" EXACT [] +synonym: "tRNA (cytosine 3)-methyltransferase activity" EXACT [] +synonym: "tRNA cytosine 3-methyltransferase activity" EXACT [] +synonym: "tRNA cytosine-3-methyltransferase activity" EXACT [] +is_a: GO:0016427 ! tRNA (cytosine) methyltransferase activity + +[Term] +id: GO:0052736 +name: beta-glucanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds." [Wikipedia:Beta-glucan] +synonym: "beta-D-glucanase activity" EXACT [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +creation_date: 2011-08-19T03:40:56Z + +[Term] +id: GO:0052737 +name: pyruvate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2." [EC:1.2.5.1] +synonym: "pyruvate dehydrogenase activity" BROAD [EC:1.2.5.1] +synonym: "pyruvate:ubiquinone oxidoreductase activity" EXACT systematic_synonym [EC:1.2.5.1] +synonym: "pyruvate:ubiquinone-8-oxidoreductase activity" EXACT [EC:1.2.5.1] +synonym: "pyruvic dehydrogenase activity" BROAD [EC:1.2.5.1] +xref: EC:1.2.5.1 +xref: KEGG_REACTION:R03145 +xref: MetaCyc:RXN-11496 +xref: RHEA:27405 +is_a: GO:0052738 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor + +[Term] +id: GO:0052738 +name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound." [EC:1.2.5] +xref: EC:1.2.5 +is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors + +[Term] +id: GO:0052739 +name: phosphatidylserine 1-acylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid." [KEGG_REACTION:R04034] +synonym: "phosphatidylserine-specific phospholipase A1 activity" BROAD [EC:3.1.1.32] +xref: EC:3.1.1.32 +xref: KEGG_REACTION:R04034 +xref: Reactome:R-HSA-8869425 "PLA1A hydrolyses PS to 2-acyl LPS" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0052740 +name: 1-acyl-2-lysophosphatidylserine acylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate." [BRENDA:3.1.1.32] +synonym: "phosphatidylserine-specific phospholipase A1 activity" BROAD [EC:3.1.1.32] +xref: EC:3.1.1.32 +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0052741 +name: (R)-limonene 6-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+." [EC:1.14.14.53, RHEA:18957] +synonym: "(+)-limonene 6-monooxygenase activity" EXACT [EC:1.14.14.53] +synonym: "(+)-limonene-6-hydroxylase activity" EXACT [EC:1.14.14.53] +synonym: "(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity" EXACT systematic_synonym [EC:1.14.14.53] +xref: EC:1.14.14.53 +xref: KEGG_REACTION:R06119 +xref: MetaCyc:1.14.13.84-RXN +xref: RHEA:18957 +is_a: GO:0019113 ! limonene monooxygenase activity + +[Term] +id: GO:0052742 +name: phosphatidylinositol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate." [GOC:ai] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +relationship: part_of GO:0046854 ! phosphatidylinositol phosphorylation +created_by: ai +creation_date: 2011-09-14T01:21:47Z + +[Term] +id: GO:0052743 +name: inositol tetrakisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate." [GOC:ai] +is_a: GO:0052745 ! inositol phosphate phosphatase activity +created_by: ai +creation_date: 2011-09-14T01:31:39Z + +[Term] +id: GO:0052744 +name: phosphatidylinositol monophosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate." [GOC:ai] +is_a: GO:0052866 ! phosphatidylinositol phosphate phosphatase activity +created_by: ai +creation_date: 2011-09-14T01:36:39Z + +[Term] +id: GO:0052745 +name: inositol phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate." [GOC:ai] +is_a: GO:0016791 ! phosphatase activity +created_by: ai +creation_date: 2011-09-14T01:50:04Z + +[Term] +id: GO:0052746 +name: inositol phosphorylation +namespace: biological_process +def: "The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms." [ISBN:0198506732] +synonym: "inositol and derivative phosphorylation" RELATED [] +synonym: "myo-inositol and derivative phosphorylation" RELATED [] +synonym: "myo-inositol phosphorylation" NARROW [] +is_a: GO:0006020 ! inositol metabolic process +is_a: GO:0046835 ! carbohydrate phosphorylation +created_by: ai +creation_date: 2011-09-14T01:55:23Z + +[Term] +id: GO:0052747 +name: sinapyl alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+." [GOC:mengo_curators, MetaCyc:RXN-1125] +synonym: "sinapyl-alcohol dehydrogenase activity" EXACT [EC:1.1.1.195] +synonym: "sinapyl-alcohol:NADP+ oxidoreductase activity" EXACT systematic_synonym [EC:1.1.1.195] +xref: EC:1.1.1.195 +xref: KEGG_REACTION:R03918 +xref: MetaCyc:RXN-1125 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +creation_date: 2011-09-21T12:42:06Z + +[Term] +id: GO:0052748 +name: baicalin beta-D-glucuronidase activity +namespace: molecular_function +def: "Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate." [GOC:mengo_curators, RHEA:28130] +synonym: "5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity" EXACT [EC:3.2.1.167] +synonym: "baicalinase activity" BROAD [EC:3.2.1.167] +xref: EC:3.2.1.167 +xref: KEGG_REACTION:R09533 +xref: MetaCyc:RXN-11760 +xref: RHEA:28130 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-09-21T12:58:43Z + +[Term] +id: GO:0052749 +name: glucose-6-phosphate dehydrogenase (coenzyme F420) activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420." [EC:1.1.98.2, GOC:mengo_curators, RHEA:27294] +synonym: "coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity" EXACT [EC:1.1.98.2] +synonym: "D-glucose-6-phosphate:F420 1-oxidoreductase activity" EXACT systematic_synonym [EC:1.1.98.2] +synonym: "F420-dependent glucose-6-phosphate dehydrogenase activity" EXACT [EC:1.1.98.2] +xref: EC:1.1.98.2 +xref: KEGG_REACTION:R09550 +xref: MetaCyc:RXN-11283 +xref: RHEA:27294 +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +created_by: ai +creation_date: 2011-09-21T01:21:54Z + +[Term] +id: GO:0052750 +name: reactive-black-5:hydrogen-peroxide oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O." [KEGG_REACTION:R07612, MetaCyc:RXN-8666] +synonym: "versatile peroxidase activity" BROAD [EC:1.11.1.16] +xref: EC:1.11.1.16 +xref: KEGG_REACTION:R07612 +xref: MetaCyc:RXN-8666 +is_a: GO:0004601 ! peroxidase activity +created_by: ai +creation_date: 2011-09-21T02:33:34Z + +[Term] +id: GO:0052751 +name: GDP-mannose hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate." [PMID:16766526] +synonym: "GDP-mannose pyrophosphatase activity" RELATED [PMID:16766526] +is_a: GO:0016462 ! pyrophosphatase activity +created_by: ai +creation_date: 2011-09-21T04:11:30Z + +[Term] +id: GO:0052752 +name: reduced coenzyme F420:heterodisulfide oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH." [GOC:mengo_curators, PMID:9914308] +synonym: "coenzyme F420-dependent heterodisulfide oxidoreductase activity" EXACT [PMID:9914308] +synonym: "F420-dependent heterodisulfide oxidoreductase activity" EXACT [PMID:9914308] +synonym: "F420H2:heterodisulfide oxidoreductase activity" EXACT [] +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors +created_by: ai +creation_date: 2011-09-21T04:21:16Z + +[Term] +id: GO:0052753 +name: propan-2-ol:coenzyme F420 oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420." [GOC:mengo_curators, PMID:15016352, PMID:1879431, PMID:8706724] +synonym: "F420-dependent propan-2-ol dehydrogenase activity" EXACT [] +synonym: "F420-dependent secondary alcohol dehydrogenase activity" BROAD [] +synonym: "isopropanol:coenzyme F420 oxidoreductase activity" EXACT [] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +creation_date: 2011-09-21T05:15:28Z + +[Term] +id: GO:0052754 +name: GTP:coenzyme F420 guanyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate." [GOC:mengo_curators, MetaCyc:MONOMER-13942, MetaCyc:RXN-9385] +synonym: "coenzyme F390-G synthetase activity" EXACT [] +synonym: "GTP:coenzyme F420 guanylyltransferase activity" EXACT [] +is_a: GO:0070568 ! guanylyltransferase activity +created_by: ai +creation_date: 2011-09-22T03:25:30Z + +[Term] +id: GO:0052755 +name: reduced coenzyme F420:quinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone." [GOC:mengo_curators, PMID:10971593, PMID:8055920] +synonym: "F420H2-dependent quinone oxidoreductase activity" EXACT [] +synonym: "F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity" EXACT [] +synonym: "F420H2:quinone oxidoreductase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity +created_by: ai +creation_date: 2011-09-22T04:08:13Z + +[Term] +id: GO:0052756 +name: chitobiose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units." [GOC:mengo_curators, PMID:15274915, Wikipedia:chitobiose] +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity +created_by: ai +creation_date: 2011-09-27T04:04:53Z + +[Term] +id: GO:0052757 +name: chondroitin hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]." [GOC:mengo_curators, PMID:18390555] +synonym: "chondroitin endo-beta-galactosaminidase activity" EXACT [PMID:18390555] +is_a: GO:0033931 ! endogalactosaminidase activity +created_by: ai +creation_date: 2011-09-28T10:31:53Z + +[Term] +id: GO:0052758 +name: coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, PMID:11995829, UM-BBD_reactionID:r1065] +synonym: "coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity" EXACT [] +synonym: "TNP reductase activity" BROAD [] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r1065 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +created_by: ai +creation_date: 2011-09-28T11:06:03Z + +[Term] +id: GO:0052759 +name: coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, UM-BBD_reactionID:r1066] +synonym: "coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity" EXACT [] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r1066 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +creation_date: 2011-09-28T01:50:17Z + +[Term] +id: GO:0052760 +name: coenzyme F420-dependent 2,4-dinitrophenol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction." [GOC:mengo_curators, PMID:11995829, UM-BBD_reactionID:r1071] +synonym: "coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity" EXACT [] +synonym: "DNP reductase activity" BROAD [] +xref: EC:1.3.99 +xref: UM-BBD_reactionID:r1071 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +created_by: ai +creation_date: 2011-09-28T02:47:31Z + +[Term] +id: GO:0052761 +name: exo-1,4-beta-D-glucosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units." [EC:3.2.1.165, GOC:mengo_curators, MetaCyc:3.2.1.165-RXN] +synonym: "chitosan exo-1,4-beta-D-glucosaminidase activity" EXACT [KEGG_REACTION:R08715] +synonym: "chitosan glucosaminohydrolase activity" EXACT [KEGG_REACTION:R08715] +synonym: "exo-beta-D-glucosaminidase activity" EXACT [EC:3.2.1.165] +synonym: "exochitosanase activity" EXACT [EC:3.2.1.165] +xref: EC:3.2.1.165 +xref: KEGG_REACTION:R08715 +xref: MetaCyc:3.2.1.165-RXN +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-09-28T03:30:54Z + +[Term] +id: GO:0052762 +name: gellan lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha)." [GOC:mengo_curators, MetaCyc:RXN-12269] +xref: EC:4.2.2.25 +xref: MetaCyc:RXN-12269 +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides +created_by: ai +creation_date: 2011-09-29T03:19:25Z + +[Term] +id: GO:0052763 +name: ulvan lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end." [GOC:mengo_curators, PMID:9468631] +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides +created_by: ai +creation_date: 2011-09-29T03:39:23Z + +[Term] +id: GO:0052764 +name: exo-oligoalginate lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends." [GOC:mengo_curators, PMID:20925655] +xref: EC:4.2.2.26 +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides +created_by: ai +creation_date: 2011-09-29T04:05:44Z + +[Term] +id: GO:0052765 +name: reduced coenzyme F420 oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O." [GOC:mengo_curators, PMID:15340796] +synonym: "coenzyme F420H2 oxidase activity" EXACT [] +synonym: "F420H2 oxidase activity" EXACT [] +synonym: "F420H2:oxygen oxidoreductase activity" EXACT [] +is_a: GO:0016491 ! oxidoreductase activity +created_by: ai +creation_date: 2011-09-29T04:33:54Z + +[Term] +id: GO:0052766 +name: mannoside alpha-1,4-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides." [GOC:mengo_curators, PMID:20081828] +synonym: "alpha-1,4-exomannosidase activity" BROAD [] +synonym: "alpha-1,4-mannosidase activity" BROAD [] +synonym: "mannoside alpha-1,4-exomannosidase activity" EXACT [] +synonym: "mannoside exo-alpha-1,4-mannosidase activity" EXACT [] +is_a: GO:0004559 ! alpha-mannosidase activity +created_by: ai +creation_date: 2011-09-30T12:55:24Z + +[Term] +id: GO:0052767 +name: mannosyl-oligosaccharide 1,6-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide." [GOC:mengo_curators, PMID:1849817, PMID:2338081] +synonym: "1,6-alpha-mannosidase activity" BROAD [] +synonym: "1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] +synonym: "alpha-1,6-mannosidase activity" BROAD [] +synonym: "alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity +created_by: ai +creation_date: 2011-09-30T12:55:24Z + +[Term] +id: GO:0052768 +name: mannosyl-oligosaccharide 1,3-alpha-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide." [GOC:mengo_curators, PMID:1849817, PMID:2338081] +synonym: "1,3-alpha-mannosidase activity" BROAD [] +synonym: "1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] +synonym: "alpha-1,3-mannosidase activity" BROAD [] +synonym: "alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] +xref: EC:3.1.1 +is_a: GO:0015924 ! mannosyl-oligosaccharide mannosidase activity +created_by: ai +creation_date: 2011-09-30T12:55:24Z + +[Term] +id: GO:0052769 +name: beta-6-sulfate-N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative." [GOC:mengo_curators, PMID:15716424] +synonym: "beta-6-SO3-N-acetylglucosaminidase activity" BROAD [] +synonym: "exosulfoglycosidase activity" BROAD [] +synonym: "sulfoglycosidase activity" BROAD [] +synonym: "sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity" EXACT [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-09-30T12:55:24Z + +[Term] +id: GO:0052770 +name: coenzyme F390-A hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420." [GOC:mengo_curators, PMID:8536708, PMID:9352911] +synonym: "8-hydroxyadenylylated-coenzyme F420 hydrolase activity" EXACT [] +is_a: GO:0016787 ! hydrolase activity +created_by: ai +creation_date: 2011-10-03T12:00:00Z + +[Term] +id: GO:0052771 +name: coenzyme F390-G hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420." [GOC:mengo_curators, PMID:8536708, PMID:9352911] +synonym: "8-hydroxyguanylylated-coenzyme F420 hydrolase activity" EXACT [] +is_a: GO:0016787 ! hydrolase activity +created_by: ai +creation_date: 2011-10-03T12:00:00Z + +[Term] +id: GO:0052772 +name: brefeldin A esterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone." [GOC:mengo_curators, PMID:10201402, PMID:8106385] +synonym: "BFA esterase activity" BROAD [] +synonym: "brefeldin A hydrolase activity" EXACT [] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: ai +creation_date: 2011-10-03T12:01:00Z + +[Term] +id: GO:0052773 +name: diacetylchitobiose deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc)." [GOC:bf, GOC:mengo_curators, MetaCyc:RXN-12543, PMID:15136574, PMID:16232910, PMID:16736587] +comment: In this reaction N,N'-diacetylchitobiose is deacetylated at the non-reducing residue to produce 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc). This is in contrast to EC:3.5.1.105 in which N,N'-diacetylchitobiose is deacetylated at the reducing residue to produce 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine (GlcNAc-GlcN). For the latter reaction, see GO:0036311. +synonym: "N,N'-diacetylchitobiose deacetylase (nonreducing end)" EXACT [MetaCyc:RXN-12543] +xref: MetaCyc:RXN-12543 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: ai +creation_date: 2011-10-03T12:01:05Z + +[Term] +id: GO:0052774 +name: glucosyl-N-acetylglucosamine glucosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine." [GOC:mengo_curators, PMID:15136574, PMID:16232910, PMID:16736587] +is_a: GO:0015929 ! hexosaminidase activity +created_by: ai +creation_date: 2011-10-03T12:01:05Z + +[Term] +id: GO:0052775 +name: endo-1,3-alpha-L-rhamnosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain." [GOC:mengo_curators, PMID:10439404] +synonym: "endo-(1,3)-alpha-L-rhamnosidase activity" EXACT [] +synonym: "endo-(1->3)-alpha-L-rhamnosidase activity" EXACT [] +synonym: "endorhamnosidase activity" BROAD [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-10-05T03:30:33Z + +[Term] +id: GO:0052776 +name: diacetylchitobiose catabolic process to glucosamine and acetate +namespace: biological_process +def: "The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate." [GOC:bf, GOC:mengo_curators, MetaCyc:PWY-6855, PMID:15136574, PMID:16232910, PMID:16736587] +is_a: GO:0006041 ! glucosamine metabolic process +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0052777 ! diacetylchitobiose catabolic process +relationship: has_part GO:0050119 ! N-acetylglucosamine deacetylase activity +relationship: has_part GO:0052761 ! exo-1,4-beta-D-glucosaminidase activity +relationship: has_part GO:0052773 ! diacetylchitobiose deacetylase activity + +[Term] +id: GO:0052777 +name: diacetylchitobiose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products." [PMID:22797760] +synonym: "diacetylchitobiose catabolism" EXACT [GOC:obol] +is_a: GO:0052778 ! diacetylchitobiose metabolic process +is_a: GO:0052782 ! amino disaccharide catabolic process + +[Term] +id: GO:0052778 +name: diacetylchitobiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose." [PMID:22797760] +synonym: "diacetylchitobiose metabolism" EXACT [GOC:obol] +is_a: GO:0052779 ! amino disaccharide metabolic process + +[Term] +id: GO:0052779 +name: amino disaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions." [GOC:curators] +is_a: GO:1901135 ! carbohydrate derivative metabolic process +creation_date: 2011-10-03T08:47:05Z + +[Term] +id: GO:0052780 +name: chitobiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine." [GOC:curators] +is_a: GO:0052779 ! amino disaccharide metabolic process +created_by: ai +creation_date: 2011-10-03T08:48:09Z + +[Term] +id: GO:0052781 +name: chitobiose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine." [GOC:curators] +is_a: GO:0052782 ! amino disaccharide catabolic process +created_by: ai +creation_date: 2011-10-03T08:54:17Z + +[Term] +id: GO:0052782 +name: amino disaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions." [GOC:curators] +is_a: GO:0052779 ! amino disaccharide metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +created_by: ai +creation_date: 2011-10-03T08:56:04Z + +[Term] +id: GO:0052783 +name: reuteran metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages." [PMID:15256553, PMID:16000808] +is_a: GO:0030978 ! alpha-glucan metabolic process +created_by: ai +creation_date: 2011-10-04T09:16:35Z + +[Term] +id: GO:0052784 +name: reuteran biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages." [GOC:mengo_curators, PMID:15256553, PMID:16000808] +synonym: "reuteransucrase-mediated reuteran biosynthesis" NARROW [] +is_a: GO:0030979 ! alpha-glucan biosynthetic process +is_a: GO:0052783 ! reuteran metabolic process +created_by: ai +creation_date: 2011-10-04T09:20:35Z + +[Term] +id: GO:0052785 +name: cellulose catabolism by endo-processive cellulases +namespace: biological_process +def: "The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments." [GOC:mengo_curators, PMID:18035374] +synonym: "endo-processive cellulase activity" RELATED [] +is_a: GO:0030245 ! cellulose catabolic process +created_by: ai +creation_date: 2011-10-04T09:31:16Z + +[Term] +id: GO:0052786 +name: alpha-linked polysaccharide catabolism to maltotriose +namespace: biological_process +def: "The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose." [GOC:mengo_curators, PMID:7511484, PMID:9406414] +synonym: "alpha-amylase-mediated polysaccharide catabolism, producing maltotriose" EXACT [] +synonym: "maltotriose-forming alpha-amylase activity" RELATED [] +is_a: GO:0000272 ! polysaccharide catabolic process +created_by: ai +creation_date: 2011-10-04T09:59:59Z + +[Term] +id: GO:0052787 +name: alpha-linked polysaccharide catabolism to maltopentaose +namespace: biological_process +def: "The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose." [GOC:mengo_curators, PMID:7511484, PMID:9406414] +synonym: "alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose" EXACT [] +synonym: "maltopentaose-forming alpha-amylase activity" RELATED [] +is_a: GO:0000272 ! polysaccharide catabolic process +created_by: ai +creation_date: 2011-10-04T10:06:44Z + +[Term] +id: GO:0052788 +name: d-4,5 unsaturated beta-glucuronyl hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue." [GOC:mengo_curators, PMID:12729728] +synonym: "unsaturated beta-glucuronyl hydrolase activity" EXACT [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-10-04T12:59:37Z + +[Term] +id: GO:0052789 +name: mannan 1,3-beta-mannosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose." [EC:3.2.1.78, GOC:mengo_curators] +synonym: "1,3-beta-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.78] +synonym: "beta-1,3-mannan 3-mannanohydrolase activity" EXACT [EC:3.2.1.78] +synonym: "exo-1,3-beta-mannanase activity" EXACT [EC:3.2.1.78] +synonym: "exo-1,3-mannanase activity" EXACT [EC:3.2.1.78] +synonym: "exo-beta-1,3-mannase activity" EXACT [EC:3.2.1.78] +is_a: GO:0004567 ! beta-mannosidase activity +created_by: ai +creation_date: 2011-10-04T01:11:41Z + +[Term] +id: GO:0052790 +name: chitooligosaccharide deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions." [GOC:mengo_curators, PMID:8421697, PMID:8986807] +xref: EC:3.5.1 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: ai +creation_date: 2011-10-04T03:48:35Z + +[Term] +id: GO:0052791 +name: 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain." [GOC:mengo_curators, PMID:21247893] +synonym: "2-keto-3-deoxynononic acid sialidase activity" EXACT [] +is_a: GO:0016997 ! alpha-sialidase activity +created_by: ai +creation_date: 2011-10-04T04:53:49Z + +[Term] +id: GO:0052792 +name: endo-xylogalacturonan hydrolase activity +namespace: molecular_function +def: "Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position." [GOC:mengo_curators, PMID:10618200] +synonym: "endo-galacturonase activity" BROAD [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: ai +creation_date: 2011-10-05T03:57:30Z + +[Term] +id: GO:0052793 +name: pectin acetylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin." [GOC:mengo_curators, PMID:9218776] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: ai +creation_date: 2011-10-05T05:17:21Z + +[Term] +id: GO:0052794 +name: exo-alpha-(2->3)-sialidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators] +synonym: "exo-alpha-(2,3)-sialidase activity" EXACT [] +synonym: "exo-alpha-2,3-sialidase activity" EXACT [] +xref: EC:3.2.1.18 +is_a: GO:0004308 ! exo-alpha-sialidase activity + +[Term] +id: GO:0052795 +name: exo-alpha-(2->6)-sialidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators] +synonym: "exo-alpha-(2,6)-sialidase activity" EXACT [] +synonym: "exo-alpha-2,6-sialidase activity" EXACT [] +xref: EC:3.2.1.18 +is_a: GO:0004308 ! exo-alpha-sialidase activity + +[Term] +id: GO:0052796 +name: exo-alpha-(2->8)-sialidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates." [EC:3.2.1.18, GOC:mengo_curators] +synonym: "exo-alpha-(2,8)-sialidase activity" EXACT [] +synonym: "exo-alpha-2,8-sialidase activity" EXACT [] +xref: EC:3.2.1.18 +is_a: GO:0004308 ! exo-alpha-sialidase activity + +[Term] +id: GO:0052797 +name: 4-O-methyl-glucuronoyl methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X]." [GOC:mengo_curators, PMID:16876163] +synonym: "glucuronoyl esterase activity" BROAD [PMID:16876163] +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0052798 +name: beta-galactoside alpha-2,3-sialyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor." [GOC:mengo_curators, PMID:7826016, PMID:8405811] +synonym: "trans-sialidase activity" BROAD [] +is_a: GO:0008373 ! sialyltransferase activity + +[Term] +id: GO:0052799 +name: coenzyme F420-dependent bicyclic nitroimidazole catabolic process +namespace: biological_process +def: "The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates." [GOC:mengo_curators, PMID:16387854, PMID:19039139] +synonym: "coenzyme F420-dependent nitroimidazole breakdown" EXACT [] +synonym: "coenzyme F420-dependent nitroimidazole catabolism" EXACT [] +synonym: "coenzyme F420-dependent nitroimidazole reduction" EXACT [] +synonym: "coenzyme F420-dependent nitroreductase activity" RELATED [] +is_a: GO:0052800 ! bicyclic nitroimidazole catabolic process + +[Term] +id: GO:0052800 +name: bicyclic nitroimidazole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole." [PMID:16387854, PMID:19039139] +synonym: "bicyclic nitroimidazole breakdown" EXACT [] +synonym: "bicyclic nitroimidazole catabolism" EXACT [] +synonym: "bicyclic nitroimidazole degradation" EXACT [] +is_a: GO:0052801 ! bicyclic nitroimidazole metabolic process +is_a: GO:0052804 ! nitroimidazole catabolic process + +[Term] +id: GO:0052801 +name: bicyclic nitroimidazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring." [PMID:16387854, PMID:19039139] +synonym: "bicyclic nitroimidazole metabolism" EXACT [] +is_a: GO:0052802 ! nitroimidazole metabolic process + +[Term] +id: GO:0052802 +name: nitroimidazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring." [PMID:16387854, PMID:19039139] +synonym: "nitroimidazole metabolism" EXACT [] +is_a: GO:0052803 ! imidazole-containing compound metabolic process + +[Term] +id: GO:0052803 +name: imidazole-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." [GOC:curators] +synonym: "imidazole metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0052804 +name: nitroimidazole catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring." [PMID:16387854, PMID:19039139] +synonym: "nitroimidazole breakdown" EXACT [] +synonym: "nitroimidazole catabolism" EXACT [] +synonym: "nitroimidazole degradation" EXACT [] +is_a: GO:0052805 ! imidazole-containing compound catabolic process + +[Term] +id: GO:0052805 +name: imidazole-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." [GOC:curators] +synonym: "imidazole breakdown" EXACT [] +synonym: "imidazole catabolism" EXACT [] +synonym: "imidazole degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0052803 ! imidazole-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process + +[Term] +id: GO:0052806 +name: sulfite reductase (coenzyme F420) activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:16048999] +synonym: "coenzyme F420-dependent sulfite reductase activity" EXACT [] +synonym: "coenzyme F420-sulfite reductase activity" EXACT [] +synonym: "hydrogen-sulfide:coenzyme F420 oxidoreductase activity" EXACT [] +synonym: "sulfite:reduced coenzyme F420 reductase activity" EXACT [] +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors +created_by: ai +creation_date: 2011-09-22T04:08:13Z + +[Term] +id: GO:0052807 +name: aflatoxin reductase (coenzyme F420) activity +namespace: molecular_function +def: "Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:20807200] +synonym: "aflatoxin:coenzyme F420 oxidoreductase activity" EXACT [] +synonym: "aflatoxin:reduced coenzyme F420 reductase activity" EXACT [] +synonym: "coenzyme F420-aflatoxin reductase activity" EXACT [] +synonym: "coenzyme F420-dependent aflatoxin reductase activity" EXACT [] +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors +relationship: part_of GO:0046223 ! aflatoxin catabolic process +created_by: ai +creation_date: 2011-09-22T04:08:13Z + +[Term] +id: GO:0052808 +name: reduced coenzyme F420:NADP+ oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420." [GOC:mengo_curators, PMID:11726492] +synonym: "coenzyme F420-dependent NADP oxidoreductase activity" EXACT [] +synonym: "coenzyme F420-dependent NADP reductase activity" EXACT [] +synonym: "F420H2:NADP oxidoreductase activity" EXACT [] +synonym: "F420H2:NADP+ oxidoreductase activity" EXACT [] +synonym: "NADP+:F420 oxidoreductase activity" EXACT [] +xref: EC:1.5.1.40 +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H +created_by: ai +creation_date: 2011-09-22T04:08:13Z + +[Term] +id: GO:0052809 +name: acharan sulfate lyase activity +namespace: molecular_function +def: "Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid." [GOC:mengo_curators, PMID:19566715] +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides +created_by: ai +creation_date: 2011-09-26T02:58:28Z + +[Term] +id: GO:0052810 +name: 1-phosphatidylinositol-5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+)." [PMID:12270933, PMID:9660759, RHEA:44680] +synonym: "1-phosphatidylinositol 5-kinase activity" EXACT [] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity" EXACT [] +xref: Reactome:R-HSA-1675810 "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane" +xref: Reactome:R-HSA-1675866 "PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane" +xref: RHEA:44680 +is_a: GO:0052742 ! phosphatidylinositol kinase activity +created_by: ai +creation_date: 2011-10-21T03:37:20Z + +[Term] +id: GO:0052811 +name: 1-phosphatidylinositol-3-phosphate 4-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)." [PMID:9211928, PMID:9367159, PMID:9660759] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity" EXACT [] +synonym: "phosphatidylinositol 3-phosphate 4-kinase activity" EXACT [] +xref: Reactome:R-HSA-1676145 "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane" +is_a: GO:0016307 ! phosphatidylinositol phosphate kinase activity +created_by: ai +creation_date: 2011-10-21T03:47:58Z + +[Term] +id: GO:0052812 +name: phosphatidylinositol-3,4-bisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)." [EC:2.7.1.153] +synonym: "ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.153] +xref: EC:2.7.1.153 +xref: Reactome:R-HSA-1675773 "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane" +is_a: GO:0052813 ! phosphatidylinositol bisphosphate kinase activity +created_by: ai +creation_date: 2011-10-21T03:52:02Z + +[Term] +id: GO:0052813 +name: phosphatidylinositol bisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate." [GOC:ai] +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +relationship: part_of GO:0046854 ! phosphatidylinositol phosphorylation +created_by: ai +creation_date: 2011-10-21T03:55:36Z + +[Term] +id: GO:0052814 +name: medium-chain-aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons." [EC:1.2.1.48] +synonym: "medium-chain aliphatic aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] +synonym: "medium-chain fatty aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] +synonym: "medium-chain-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.48] +xref: EC:1.2.1 +is_a: GO:0004029 ! aldehyde dehydrogenase (NAD+) activity +creation_date: 2011-10-25T03:04:41Z + +[Term] +id: GO:0052815 +name: medium-chain acyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length." [EC:3.1.2.19] +synonym: "medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "medium-chain hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "medium-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] +is_a: GO:0047617 ! acyl-CoA hydrolase activity +created_by: ai +creation_date: 2011-10-25T05:26:29Z + +[Term] +id: GO:0052816 +name: long-chain acyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length." [EC:3.1.2.19] +synonym: "long-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "long-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "long-chain hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "long-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] +is_a: GO:0047617 ! acyl-CoA hydrolase activity +created_by: ai +creation_date: 2011-10-25T05:31:11Z + +[Term] +id: GO:0052817 +name: very long chain acyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18." [EC:3.1.2.19] +synonym: "very long-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "very long-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "very long-chain hydrolase activity" EXACT [EC:3.1.2.19] +synonym: "very long-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] +is_a: GO:0052816 ! long-chain acyl-CoA hydrolase activity +created_by: ai +creation_date: 2011-10-27T12:18:28Z + +[Term] +id: GO:0052818 +name: heteroglycan 3-alpha-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48, MetaCyc:RXN-7992] +synonym: "GDP mannose 3-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "heteropolysaccharide 3-alpha-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.48 +xref: KEGG_REACTION:R03769 +xref: MetaCyc:RXN-7992 +is_a: GO:0047264 ! heteroglycan alpha-mannosyltransferase activity +created_by: ai +creation_date: 2011-10-27T12:36:10Z + +[Term] +id: GO:0052819 +name: heteroglycan 2-alpha-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48, MetaCyc:2.4.1.48-RXN] +synonym: "GDP mannose 2-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] +synonym: "heteropolysaccharide 2-alpha-mannosyltransferase activity" EXACT [] +xref: EC:2.4.1.48 +xref: KEGG_REACTION:R03768 +xref: MetaCyc:2.4.1.48-RXN +is_a: GO:0047264 ! heteroglycan alpha-mannosyltransferase activity +created_by: ai +creation_date: 2011-10-27T12:36:19Z + +[Term] +id: GO:0052820 +name: DNA-1,N6-ethenoadenine N-glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar." [PMID:21960007] +synonym: "1,N(6)-ethenoadenine N-glycosylase activity" EXACT [] +synonym: "1,N6-ethenoadenine glycosylase activity" EXACT [] +is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity +creation_date: 2011-10-28T01:17:21Z + +[Term] +id: GO:0052821 +name: DNA-7-methyladenine glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site." [GOC:jl, PMID:16468998] +xref: EC:3.2.2.21 +xref: MetaCyc:3.2.2.21-RXN +is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity +created_by: ai +creation_date: 2011-10-28T02:27:39Z + +[Term] +id: GO:0052822 +name: DNA-3-methylguanine glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623] +synonym: "3-methylguanine DNA glycosylase I" RELATED [EC:3.2.2.20] +synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.20] +synonym: "deoxyribonucleate 3-methylguanine glycosidase I" RELATED [EC:3.2.2.20] +synonym: "DNA glycosidase I activity" RELATED [EC:3.2.2.20] +xref: EC:3.2.2.21 +xref: MetaCyc:3.2.2.21-RXN +is_a: GO:0043733 ! DNA-3-methylbase glycosylase activity +created_by: ai +creation_date: 2011-10-28T02:28:19Z + +[Term] +id: GO:0052823 +name: 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+." [RHEA:25046] +synonym: "(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity" EXACT systematic_synonym [EC:3.7.1.14] +synonym: "2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity" EXACT [UM-BBD_reactionID:r1622] +xref: EC:3.7.1.14 +xref: MetaCyc:RXN-12070 +xref: RHEA:25046 +xref: UM-BBD_reactionID:r1622 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances +created_by: ai +creation_date: 2011-10-28T03:28:37Z + +[Term] +id: GO:0052824 +name: dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol." [PMID:10336995] +is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity +created_by: ai +creation_date: 2011-10-28T03:57:17Z + +[Term] +id: GO:0052825 +name: inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855219 "I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol" +is_a: GO:0052827 ! inositol pentakisphosphate phosphatase activity +creation_date: 2011-11-29T09:49:22Z + +[Term] +id: GO:0052826 +name: inositol hexakisphosphate 2-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate." [EC:3.1.3.62] +synonym: "1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity" EXACT [EC:3.1.3.62] +xref: EC:3.1.3.62 +xref: Reactome:R-HSA-1855225 "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen" +is_a: GO:0004446 ! inositol-hexakisphosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T09:52:14Z + +[Term] +id: GO:0052827 +name: inositol pentakisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate." [GOC:bf] +is_a: GO:0052745 ! inositol phosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T09:55:04Z + +[Term] +id: GO:0052828 +name: inositol-3,4-bisphosphate 4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate." [GOC:mah] +xref: Reactome:R-HSA-1855202 "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol" +is_a: GO:0016312 ! inositol bisphosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T09:57:00Z + +[Term] +id: GO:0052829 +name: inositol-1,3,4-trisphosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855232 "I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol" +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T09:58:00Z + +[Term] +id: GO:0052830 +name: inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855171 "I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol" +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T10:56:59Z + +[Term] +id: GO:0052831 +name: inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate." [GOC:ai] +xref: EC:3.1.3 +xref: Reactome:R-HSA-1855159 "I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol" +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T10:58:27Z + +[Term] +id: GO:0052832 +name: inositol monophosphate 3-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25] +xref: EC:3.1.3.25 +xref: MetaCyc:MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN +xref: Reactome:R-HSA-1855210 "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol" +is_a: GO:0052834 ! inositol monophosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T11:00:09Z + +[Term] +id: GO:0052833 +name: inositol monophosphate 4-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25] +synonym: "inositol-1(or 4)-monophosphatase activity" BROAD [EC:3.1.3.25] +synonym: "myo-inositol-1(or 4)-monophosphatase activity" BROAD [] +synonym: "myo-inositol-1(or 4)-phosphate phosphohydrolase activity" BROAD [] +xref: EC:3.1.3.25 +xref: MetaCyc:RXN-10952 +xref: Reactome:R-HSA-1855211 "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol" +is_a: GO:0052834 ! inositol monophosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T11:02:15Z + +[Term] +id: GO:0052834 +name: inositol monophosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25] +synonym: "inositol phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "inositol-1(or 4)-monophosphatase activity" BROAD [EC:3.1.3.25] +synonym: "inositol-phosphate phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "L-myo-inositol-phosphate phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol monophosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol-1(or 4)-phosphate phosphohydrolase activity" BROAD [EC:3.1.3.25] +synonym: "myo-inositol-phosphatase activity" EXACT [EC:3.1.3.25] +synonym: "myo-inositol-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.25] +xref: EC:3.1.3.25 +xref: MetaCyc:RXN-10949 +is_a: GO:0052745 ! inositol phosphate phosphatase activity +created_by: ai +creation_date: 2011-11-29T11:15:58Z + +[Term] +id: GO:0052835 +name: inositol-3,4,6-trisphosphate 1-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)." [EC:2.7.1.134] +synonym: "1D-myo-inositol-trisphosphate 1-kinase activity" BROAD [] +synonym: "ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.127] +synonym: "inositol 3,4,6-trisphosphate 1-kinase activity" EXACT [] +synonym: "inositol-trisphosphate 1-kinase activity" BROAD [] +synonym: "ins(3,4,6)P(3) 1-kinase activity" EXACT [EC:2.7.1.127] +synonym: "Ins(3,4,6)P3 1-kinase activity" EXACT [EC:2.7.1.127] +synonym: "IP3 1-kinase activity" BROAD [EC:2.7.1.127] +xref: EC:2.7.1 +xref: Reactome:R-HSA-1855169 "I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol" +is_a: GO:0051766 ! inositol trisphosphate kinase activity +created_by: ai +creation_date: 2011-11-29T01:06:01Z + +[Term] +id: GO:0052836 +name: inositol 5-diphosphate pentakisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate." [PMID:11502751, PMID:18355727] +xref: Reactome:R-HSA-1855158 "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol" +xref: Reactome:R-HSA-1855224 "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +created_by: ai +creation_date: 2011-11-29T01:14:22Z + +[Term] +id: GO:0052837 +name: thiazole biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position." [GOC:curators] +synonym: "thiazole anabolism" EXACT [] +synonym: "thiazole biosynthesis" EXACT [] +synonym: "thiazole formation" EXACT [] +synonym: "thiazole synthesis" EXACT [] +is_a: GO:0018131 ! oxazole or thiazole biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0052838 ! thiazole metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: ai +creation_date: 2011-11-29T03:33:05Z + +[Term] +id: GO:0052838 +name: thiazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position." [GOC:curators] +synonym: "thiazole metabolism" EXACT [] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0046484 ! oxazole or thiazole metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: ai +creation_date: 2011-11-29T03:35:50Z + +[Term] +id: GO:0052839 +name: inositol diphosphate tetrakisphosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate." [PMID:10827188, PMID:11502751, PMID:18355727] +xref: Reactome:R-HSA-1855193 "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol" +xref: Reactome:R-HSA-1855230 "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus" +is_a: GO:0016301 ! kinase activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +created_by: ai +creation_date: 2011-11-29T04:14:22Z + +[Term] +id: GO:0052840 +name: inositol diphosphate tetrakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate." [MetaCyc:RXN-10963, PMID:10827188, PMID:11502751] +xref: EC:3.6.1.52 +xref: MetaCyc:RXN-10963 +xref: Reactome:R-HSA-1855166 "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol" +is_a: GO:0016462 ! pyrophosphatase activity +created_by: ai +creation_date: 2011-11-29T04:14:22Z + +[Term] +id: GO:0052841 +name: inositol bisdiphosphate tetrakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate." [MetaCyc:RXN-10965, MetaCyc:RXN-10975, MetaCyc:RXN-10976, PMID:10827188, PMID:11502751] +xref: Reactome:R-HSA-1855165 "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol" +xref: Reactome:R-HSA-2023973 "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol" +is_a: GO:0016462 ! pyrophosphatase activity +created_by: ai +creation_date: 2011-11-29T04:14:22Z + +[Term] +id: GO:0052842 +name: inositol diphosphate pentakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate." [MetaCyc:RXN-10964, MetaCyc:RXN-10977, MetaCyc:RXN-10978, PMID:10827188, PMID:11502751] +xref: EC:3.6.1.52 +xref: KEGG_REACTION:R05779 +xref: Reactome:R-HSA-1855198 "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol" +xref: Reactome:R-HSA-2023971 "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol" +is_a: GO:0016462 ! pyrophosphatase activity +created_by: ai +creation_date: 2011-11-29T04:14:22Z + +[Term] +id: GO:0052843 +name: inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10977, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10977 +is_a: GO:0052842 ! inositol diphosphate pentakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T10:42:00Z + +[Term] +id: GO:0052844 +name: inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10978, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10978 +is_a: GO:0052842 ! inositol diphosphate pentakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T10:59:26Z + +[Term] +id: GO:0052845 +name: inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+." [MetaCyc:RXN-10964, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10964 +is_a: GO:0052842 ! inositol diphosphate pentakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T10:59:20Z + +[Term] +id: GO:0052846 +name: inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10965, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10965 +is_a: GO:0052841 ! inositol bisdiphosphate tetrakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T11:02:23Z + +[Term] +id: GO:0052847 +name: inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10975, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10975 +is_a: GO:0052841 ! inositol bisdiphosphate tetrakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T11:02:23Z + +[Term] +id: GO:0052848 +name: inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+." [MetaCyc:RXN-10976, PMID:10827188, PMID:11502751] +xref: MetaCyc:RXN-10976 +is_a: GO:0052841 ! inositol bisdiphosphate tetrakisphosphate diphosphatase activity +created_by: ai +creation_date: 2011-12-05T11:02:23Z + +[Term] +id: GO:0052849 +name: NADPH-dependent curcumin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+." [MetaCyc:RXN0-6676] +xref: EC:1.3.1.n3 +xref: MetaCyc:RXN0-6676 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-12-05T11:03:23Z + +[Term] +id: GO:0052850 +name: NADPH-dependent dihydrocurcumin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+." [MetaCyc:RXN0-6677] +synonym: "dihydrocurcumin reductase (NADPH) activity" EXACT [] +xref: MetaCyc:RXN0-6677 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-12-05T11:04:23Z + +[Term] +id: GO:0052851 +name: ferric-chelate reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 Fe3+ + NADPH = 2 Fe2+ + H+ + NADP+ ." [MetaCyc:RXN0-6555] +synonym: "Fe(II):NADP+ oxidoreductase activity" EXACT [] +synonym: "ferric chelate reductase activity" BROAD [] +synonym: "ferric reductase, NADPH-dependent activity" EXACT [] +synonym: "iron chelate reductase activity" BROAD [] +synonym: "NADPH:Fe3+-EDTA reductase activity" EXACT [] +xref: EC:1.16.1.9 +xref: KEGG_REACTION:R09541 +xref: MetaCyc:RXN0-6555 +xref: RHEA:28795 +is_a: GO:0016723 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor +created_by: ai +creation_date: 2011-12-05T11:04:23Z + +[Term] +id: GO:0052852 +name: very-long-chain-(S)-2-hydroxy-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: very-long-chain (S)-2-hydroxy-acid + O2 = very-long-chain 2-oxo acid + hydrogen peroxide. Very long chain refers to a chain length of greater than 18 carbons." [EC:1.1.3.15] +synonym: "oxidase, very-long-chain L-2-hydroxy acid" EXACT [EC:1.1.3.15] +synonym: "very-long-chain L-2-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "very-long-chain L-alpha-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "very-long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase" EXACT [EC:1.1.3.15] +synonym: "very-long-chain-hydroxy-acid oxidase A activity" NARROW [EC:1.1.3.15] +synonym: "very-long-chain-hydroxy-acid oxidase B activity" NARROW [EC:1.1.3.15] +synonym: "very-long-chain-hydroxyacid oxidase A" RELATED [EC:1.1.3.15] +xref: EC:1.1.3.15 +is_a: GO:0003973 ! (S)-2-hydroxy-acid oxidase activity +creation_date: 2011-12-05T12:55:03Z + +[Term] +id: GO:0052853 +name: long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons." [EC:1.1.3.15] +synonym: "long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase" EXACT [EC:1.1.3.15] +synonym: "long-chain-hydroxy-acid oxidase A activity" NARROW [EC:1.1.3.15] +synonym: "long-chain-hydroxy-acid oxidase B activity" NARROW [EC:1.1.3.15] +synonym: "long-chain-hydroxyacid oxidase A" RELATED [EC:1.1.3.15] +synonym: "long-chain-L-2-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "long-chain-L-alpha-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "oxidase, long-chain-L-2-hydroxy acid" EXACT [EC:1.1.3.15] +xref: EC:1.1.3.15 +xref: Reactome:R-HSA-6787811 "HAO2 tetramer oxidises 2OH-PALM" +is_a: GO:0003973 ! (S)-2-hydroxy-acid oxidase activity +creation_date: 2011-12-05T12:55:03Z + +[Term] +id: GO:0052854 +name: medium-chain-(S)-2-hydroxy-acid oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: medium-chain-(S)-2-hydroxy-acid + O2 = medium-chain-2-oxo acid + hydrogen peroxide. Medium chain refers to a chain length of between 8 and 12 carbons." [EC:1.1.3.15] +synonym: "medium-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase" EXACT [EC:1.1.3.15] +synonym: "medium-chain-hydroxy-acid oxidase A activity" NARROW [EC:1.1.3.15] +synonym: "medium-chain-hydroxy-acid oxidase B activity" NARROW [EC:1.1.3.15] +synonym: "medium-chain-hydroxyacid oxidase A" RELATED [EC:1.1.3.15] +synonym: "medium-chain-L-2-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "medium-chain-L-alpha-hydroxy acid oxidase" EXACT [EC:1.1.3.15] +synonym: "oxidase, medium-chain-L-2-hydroxy acid" EXACT [EC:1.1.3.15] +xref: EC:1.1.3.15 +is_a: GO:0003973 ! (S)-2-hydroxy-acid oxidase activity +creation_date: 2011-12-05T12:55:03Z + +[Term] +id: GO:0052855 +name: ADP-dependent NAD(P)H-hydrate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate." [EC:4.2.1.93, PMID:21994945] +synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)" EXACT [EC:4.2.1.136] +synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming)" RELATED [EC:4.2.1.136] +synonym: "ADP-dependent H(4)NAD(P)OH dehydratase activity" EXACT [] +synonym: "ADP-dependent H4NAD(P)OH dehydratase activity" EXACT [] +synonym: "reduced nicotinamide adenine dinucleotide hydrate dehydratase activity" BROAD [EC:4.2.1.93] +xref: EC:4.2.1.136 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0052856 +name: NADHX epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-NADHX = (S)-NADHX." [PMID:21994945] +xref: EC:5.1.99.6 +xref: RHEA:32215 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0052857 +name: NADPHX epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX." [PMID:21994945] +xref: EC:5.1.99.6 +xref: Reactome:R-HSA-6806966 "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX" +xref: RHEA:32227 +is_a: GO:0016854 ! racemase and epimerase activity + +[Term] +id: GO:0052858 +name: peptidyl-lysine acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine." [GOC:tb] +synonym: "acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity" EXACT [] +synonym: "acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity" EXACT [] +synonym: "peptidyl-lysine N(6)-acetyltransferase activity" EXACT [] +synonym: "peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor" EXACT [] +synonym: "peptidyl-lysine N6-acetyltransferase activity" EXACT [] +is_a: GO:0008080 ! N-acetyltransferase activity + +[Term] +id: GO:0052859 +name: glucan endo-1,4-beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans." [EC:3.2.1.75] +synonym: "1,4-beta-D-glucan glucanohydrolase activity" EXACT [] +synonym: "beta-1,4-glucan 4-glucanohydrolase activity" EXACT [] +synonym: "beta-1,4-glucan hydrolase activity" EXACT [] +synonym: "beta-1,4-glucanase activity" EXACT [] +synonym: "beta-1->4-glucan hydrolase activity" EXACT [] +synonym: "endo-(1,4)-beta-D-glucanase activity" EXACT [] +synonym: "endo-(1->4)-beta-D-glucanase activity" EXACT [] +synonym: "endo-1,4-beta-D-glucanase activity" EXACT [] +synonym: "endo-1,4-beta-glucanase activity" EXACT [] +synonym: "endo-beta-1,4-glucanase activity" EXACT [] +xref: EC:3.2.1 +is_a: GO:0008422 ! beta-glucosidase activity +created_by: ai +creation_date: 2011-12-06T03:48:44Z + +[Term] +id: GO:0052860 +name: 2'-deoxymugineic-acid 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2." [EC:1.14.11.25] +synonym: "2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.25] +xref: EC:1.14.11.25 +xref: KEGG_REACTION:R07187 +xref: MetaCyc:RXN-7983 +xref: RHEA:20065 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +created_by: ai +creation_date: 2011-12-05T06:00:58Z + +[Term] +id: GO:0052861 +name: glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6] +synonym: "1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.6] +synonym: "laminaranase activity" RELATED [EC:3.2.1.6] +synonym: "laminarinase activity" RELATED [EC:3.2.1.6] +xref: EC:3.2.1.6 +xref: MetaCyc:3.2.1.6-RXN +is_a: GO:0052736 ! beta-glucanase activity +created_by: ai +creation_date: 2011-12-06T04:49:36Z + +[Term] +id: GO:0052862 +name: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group +namespace: molecular_function +def: "Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6] +synonym: "1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.6] +synonym: "laminaranase activity" RELATED [EC:3.2.1.6] +synonym: "laminarinase activity" RELATED [EC:3.2.1.6] +xref: EC:3.2.1.6 +xref: MetaCyc:3.2.1.6-RXN +is_a: GO:0052736 ! beta-glucanase activity +created_by: ai +creation_date: 2011-12-06T05:27:26Z + +[Term] +id: GO:0052863 +name: 1-deoxy-D-xylulose 5-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [GOC:curators] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolic process" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolism" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate metabolism" EXACT [] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process + +[Term] +id: GO:0052864 +name: 1-deoxy-D-xylulose 5-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [GOC:curators] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate breakdown" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolic process" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolism" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate degradation" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate breakdown" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate catabolism" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate degradation" EXACT [] +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0052863 ! 1-deoxy-D-xylulose 5-phosphate metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0052865 +name: 1-deoxy-D-xylulose 5-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis." [GOC:curators] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate anabolism" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthesis" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthetic process" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate formation" EXACT [] +synonym: "(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate synthesis" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate anabolism" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate biosynthesis" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate formation" EXACT [] +synonym: "1-deoxy-D-xylulose 5-phosphate synthesis" EXACT [] +xref: UniPathway:UPA00064 +is_a: GO:0052863 ! 1-deoxy-D-xylulose 5-phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process + +[Term] +id: GO:0052866 +name: phosphatidylinositol phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate." [GOC:ai] +synonym: "phosphoinositide phosphatase activity" EXACT [] +is_a: GO:0016791 ! phosphatase activity +created_by: ai +creation_date: 2011-12-13T01:20:17Z + +[Term] +id: GO:0052867 +name: phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate." [EC:3.1.3.-] +synonym: "phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity" BROAD [EC:3.1.3.-] +synonym: "phosphatidylinositol 1,4,5-trisphosphate phosphatase activity" BROAD [EC:3.1.3.-] +synonym: "phosphatidylinositol-trisphosphatase activity" BROAD [EC:3.1.3.-] +synonym: "PtdIns(1,4,5)P(3) phosphatase activity" BROAD [EC:3.1.3.-] +synonym: "PtdIns(1,4,5)P3 phosphatase activity" BROAD [EC:3.1.3.-] +synonym: "triphosphoinositide phosphatase activity" BROAD [EC:3.1.3.-] +synonym: "triphosphoinositide phosphomonoesterase activity" BROAD [EC:3.1.3.-] +xref: EC:3.1.3 +is_a: GO:0034594 ! phosphatidylinositol trisphosphate phosphatase activity +is_a: GO:0034595 ! phosphatidylinositol phosphate 5-phosphatase activity +creation_date: 2012-01-11T12:07:50Z + +[Term] +id: GO:0052868 +name: protein-lysine lysyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine." [PMID:20729861] +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups +created_by: ai +creation_date: 2012-01-11T03:05:27Z + +[Term] +id: GO:0052869 +name: arachidonic acid omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid." [KEGG_REACTION:R07041] +synonym: "arachidonic acid hydroxylase activity" BROAD [] +synonym: "arachidonic acid:oxygen 1-oxidoreductase activity" EXACT systematic_synonym [] +xref: EC:1.14.15.3 +xref: KEGG_REACTION:R07041 +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen +created_by: ai +creation_date: 2012-01-30T03:05:27Z + +[Term] +id: GO:0052870 +name: tocopherol omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O ." [MetaCyc:RXN-11003] +synonym: "tocopherol 13-hydroxylase activity" EXACT systematic_synonym [] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: ai +creation_date: 2012-01-30T03:06:27Z + +[Term] +id: GO:0052871 +name: alpha-tocopherol omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O ." [MetaCyc:RXN-11003] +synonym: "alpha-tocopherol 13-hydroxylase activity" EXACT [] +xref: MetaCyc:RXN-11003 +is_a: GO:0052870 ! tocopherol omega-hydroxylase activity +created_by: ai +creation_date: 2012-01-30T03:06:27Z + +[Term] +id: GO:0052872 +name: tocotrienol omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O ." [MetaCyc:RXN-11003] +synonym: "tocotrienol 13-hydroxylase activity" EXACT [] +xref: EC:1.14.13 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: ai +creation_date: 2012-01-30T03:07:27Z + +[Term] +id: GO:0052873 +name: FMN reductase (NADPH) activity +namespace: molecular_function +def: "Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+." [RHEA:21624] +synonym: "flavin mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "flavine mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "FMNH2:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH dehydrogenase (FMN) activity" EXACT [] +synonym: "NADPH(2) dehydrogenase (FMN) activity" EXACT [EC:1.5.1.29] +synonym: "NADPH(2):FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH-dependent FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH-FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH2 dehydrogenase (FMN)" EXACT [EC:1.5.1.3] +synonym: "NADPH2:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH:flavin oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADPH:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "SsuE" RELATED [EC:1.5.1.29] +xref: EC:1.5.1.38 +xref: EC:1.5.1.39 +xref: KEGG_REACTION:R05706 +xref: Reactome:R-HSA-1222399 "Iron is reduced and separates from mycobactin" +xref: RHEA:21624 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0052874 +name: FMN reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+." [RHEA:21620] +synonym: "flavin mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "flavine mononucleotide reductase activity" BROAD [EC:1.5.1.29] +synonym: "FMNH2:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH dehydrogenase (FMN) activity" EXACT [] +synonym: "NADH(2) dehydrogenase (FMN) activity" EXACT [EC:1.5.1.29] +synonym: "NADH(2):FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH-dependent FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH-FMN reductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH2 dehydrogenase (FMN)" EXACT [EC:1.5.1.3] +synonym: "NADH2:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH:flavin oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "NADH:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] +synonym: "SsuE" RELATED [EC:1.5.1.29] +xref: EC:1.5.1.39 +xref: KEGG_REACTION:R05705 +xref: RHEA:21620 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0052875 +name: riboflavin reductase (NADH) activity +namespace: molecular_function +def: "Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+." [RHEA:31455] +synonym: "flavin mononucleotide reductase activity" RELATED [EC:1.5.1.41] +synonym: "flavine mononucleotide reductase activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H-dependent FMN reductase activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H-FMN reductase activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H2 dehydrogenase (FMN) activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H2:FMN oxidoreductase activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H:FMN oxidoreductase activity" RELATED [EC:1.5.1.41] +synonym: "NAD(P)H:riboflavin oxidoreductase activity" EXACT [EC:1.5.1.41] +synonym: "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity" EXACT [EC:1.5.1.41] +synonym: "riboflavin mononucleotide reductase activity" RELATED [EC:1.5.1.41] +synonym: "riboflavine mononucleotide reductase activity" RELATED [EC:1.5.1.41] +xref: EC:1.5.1.41 +xref: KEGG_REACTION:R09750 +xref: MetaCyc:RXN-12445 +xref: RHEA:31455 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0052876 +name: methylamine dehydrogenase (amicyanin) activity +namespace: molecular_function +def: "Catalysis of the reaction: methylamine + H2O + amicyanin = formaldehyde + ammonia + reduced amicyanin." [KEGG_REACTION:R00606] +synonym: "amine dehydrogenase activity" BROAD [EC:1.4.9.1] +synonym: "amine:(acceptor) oxidoreductase (deaminating) activity" BROAD [EC:1.4.9.1] +synonym: "MADH activity" BROAD [EC:1.4.9.1] +synonym: "methylamine dehydrogenase activity" BROAD [EC:1.4.9.1] +synonym: "methylamine:amicyanin oxidoreductase (deaminating) activity" EXACT systematic_synonym [EC:1.4.9.1] +synonym: "primary-amine dehydrogenase activity" BROAD [EC:1.4.9.1] +synonym: "primary-amine:(acceptor) oxidoreductase (deaminating) activity" BROAD [EC:1.4.9.1] +xref: EC:1.4.9.1 +xref: KEGG_REACTION:R00606 +xref: UM-BBD_reactionID:r0075 +is_a: GO:0052877 ! oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor + +[Term] +id: GO:0052877 +name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor." [GOC:ai] +xref: EC:1.4.9 +is_a: GO:0016638 ! oxidoreductase activity, acting on the CH-NH2 group of donors + +[Term] +id: GO:0052878 +name: linoleate 8R-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate." [RHEA:25395] +synonym: "5,8-LDS (bifunctional enzyme) activity" RELATED [EC:1.13.11.60] +synonym: "5,8-linoleate diol synthase (bifunctional enzyme) activity" RELATED [EC:1.13.11.60] +synonym: "7,8-LDS (bifunctional enzyme) activity" RELATED [EC:1.13.11.60] +synonym: "7,8-linoleate diol synthase (bifunctional enzyme) activity" RELATED [EC:1.13.11.60] +synonym: "linoleate diol synthase activity" RELATED [EC:1.13.11.44] +xref: EC:1.13.11.60 +xref: KEGG_REACTION:R07061 +xref: MetaCyc:1.13.11.44-RXN +xref: RHEA:25395 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0052879 +name: 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate." [RHEA:25399] +synonym: "(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity" EXACT [EC:5.4.4.6] +synonym: "8-hydroperoxide isomerase activity" BROAD [EC:5.4.4.6] +synonym: "linoleate diol synthase activity" RELATED [EC:1.13.11.44] +xref: EC:5.4.4.6 +xref: KEGG_REACTION:R07062 +xref: MetaCyc:1.13.11.44-RXN +xref: RHEA:25399 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0052880 +name: oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl] +xref: EC:1.10.9 +is_a: GO:0016679 ! oxidoreductase activity, acting on diphenols and related substances as donors + +[Term] +id: GO:0052881 +name: 4-hydroxyphenylacetate 3-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O." [RHEA:30595] +synonym: "4 HPA 3-hydroxylase activity" BROAD [EC:1.14.14.9] +synonym: "4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity" EXACT systematic_synonym [] +synonym: "4-hydroxyphenylacetic acid-3-hydroxylase activity" BROAD [EC:1.14.14.9] +synonym: "p-hydroxyphenylacetate 3-hydroxylase (FAD) activity" EXACT [EC:1.14.14.9] +synonym: "p-hydroxyphenylacetate 3-hydroxylase activity" BROAD [EC:1.14.14.9] +synonym: "p-hydroxyphenylacetate hydroxylase (FAD) activity" EXACT [EC:1.14.14.9] +synonym: "p-hydroxyphenylacetate hydroxylase activity" BROAD [EC:1.14.14.9] +xref: EC:1.14.14.9 +xref: MetaCyc:RXN-8505 +xref: RHEA:30595 +xref: UM-BBD_reactionID:r0301 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0052882 +name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein." [GOC:jl] +xref: EC:1.20.9 +is_a: GO:0030613 ! oxidoreductase activity, acting on phosphorus or arsenic in donors + +[Term] +id: GO:0052883 +name: tyrosine ammonia-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate." [RHEA:24906] +synonym: "L-tyrosine ammonia-lyase activity" EXACT [EC:4.3.1.23] +synonym: "TAL activity" BROAD [EC:4.3.1.23] +synonym: "tyrase activity" BROAD [EC:4.3.1.23] +xref: EC:4.3.1.23 +xref: EC:4.3.1.25 +xref: RHEA:24906 +is_a: GO:0016841 ! ammonia-lyase activity + +[Term] +id: GO:0052884 +name: all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate." [RHEA:31775] +synonym: "all-trans-retinol isomerase:hydrolase activity" BROAD [EC:3.1.1.64] +synonym: "all-trans-retinyl-palmitate hydrolase activity" BROAD [EC:3.1.1.64] +synonym: "retinoid isomerohydrolase activity" BROAD [EC:3.1.1.64] +synonym: "retinol isomerase activity" BROAD [EC:3.1.1.64] +xref: EC:3.1.1.64 +xref: Reactome:R-HSA-2453833 "RPE65 isomero-hydrolyses atREs to 11cROL" +xref: RHEA:31775 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0052885 +name: all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid." [RHEA:31771] +synonym: "all-trans-retinol isomerase:hydrolase activity" BROAD [EC:3.1.1.64] +synonym: "all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity" EXACT [EC:3.1.1.64] +synonym: "all-trans-retinylester 11-cis isomerohydrolase activity" EXACT [EC:3.1.1.64] +synonym: "retinoid isomerohydrolase activity" BROAD [EC:3.1.1.64] +synonym: "retinol isomerase activity" BROAD [EC:3.1.1.64] +xref: EC:3.1.1.64 +xref: KEGG_REACTION:R08388 +xref: MetaCyc:RXN-12550 +xref: RHEA:31771 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +relationship: part_of GO:0042572 ! retinol metabolic process + +[Term] +id: GO:0052886 +name: 9,9'-dicis-carotene:quinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol." [EC:1.3.5.6] +synonym: "9,9'-di-cis-zeta-carotene desaturase activity" BROAD [EC:1.3.5.6] +synonym: "ZDS activity" BROAD [EC:1.3.5.6] +synonym: "zeta-carotene desaturase activity" BROAD [EC:1.3.5.6] +xref: EC:1.3.5.6 +xref: KEGG_REACTION:R09656 +xref: MetaCyc:RXN-11356 +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor + +[Term] +id: GO:0052887 +name: 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol." [EC:1.3.5.6] +synonym: "9,9'-di-cis-zeta-carotene desaturase activity" BROAD [EC:1.3.5.6] +synonym: "ZDS activity" BROAD [EC:1.3.5.6] +synonym: "zeta-carotene desaturase activity" BROAD [EC:1.3.5.6] +xref: EC:1.3.5.6 +xref: KEGG_REACTION:R09658 +xref: MetaCyc:RXN-11357 +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor + +[Term] +id: GO:0052888 +name: obsolete dihydroorotate oxidase (fumarate) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate." [EC:1.3.98.1, RHEA:30059] +comment: EC has determined that this reaction in fact does not exist and have withdrawn EC:1.3.3.1. Note: If fumarate is not shown to be involved, you may want to consider GO:0004152, dihydroorotate dehydrogenase activity (parent term); if the reaction involves fumarate, then use GO:0052888 dihydroorotate oxidase (fumarate) activity. Details at http://sourceforge.net/p/geneontology/ontology-requests/10770/ +synonym: "DHOD activity" BROAD [EC:1.3.98.1] +synonym: "DHOdase activity" BROAD [EC:1.3.98.1] +synonym: "DHodehase activity" BROAD [EC:1.3.98.1] +synonym: "dihydoorotic acid dehydrogenase activity" BROAD [EC:1.3.98.1] +synonym: "dihydroorotate dehydrogenase activity" BROAD [EC:1.3.98.1] +synonym: "dihydroorotate oxidase (fumarate) activity" EXACT [] +synonym: "dihydroorotate oxidase activity" BROAD [EC:1.3.98.1] +xref: EC:1.3.98.1 +xref: KEGG_REACTION:R01867 +xref: MetaCyc:RXN-9929 +xref: RHEA:30059 +is_obsolete: true + +[Term] +id: GO:0052889 +name: 9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene +namespace: biological_process +def: "The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene." [EC:1.3.5.6, KEGG_REACTION:R07511] +synonym: "7,9,7',9'-tetra-cis-lycopene biosynthesis from 9,9'-di-cis-zeta-carotene" EXACT [] +synonym: "9,9'-di-cis-zeta-carotene catabolism to 7,9,7',9'-tetra-cis-lycopene" EXACT [] +synonym: "9,9'-di-cis-zeta-carotene desaturase activity" EXACT [EC:1.3.5.6] +synonym: "9,9'-dicis-zeta-carotene:quinone oxidoreductase activity" EXACT [KEGG_REACTION:R07511] +synonym: "ZDS activity" BROAD [EC:1.3.5.6] +synonym: "zeta-carotene desaturase activity" BROAD [EC:1.3.5.6] +xref: KEGG_REACTION:R07511 +xref: MetaCyc:RXN-12242 +is_a: GO:0016119 ! carotene metabolic process +relationship: has_part GO:0052886 ! 9,9'-dicis-carotene:quinone oxidoreductase activity +relationship: has_part GO:0052887 ! 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity + +[Term] +id: GO:0052890 +name: oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin." [GOC:jl] +xref: EC:1.3.8 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0052891 +name: aliphatic (S)-hydroxynitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide." [EC:4.1.2.47] +synonym: "(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity" BROAD [EC:4.1.2.47] +synonym: "(S)-cyanohydrin producing hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-oxynitrilase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-selective hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "oxynitrilase activity" BROAD [EC:4.1.2.47] +xref: EC:4.1.2.47 +xref: MetaCyc:RXN-11731 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0052892 +name: aromatic (S)-hydroxynitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide." [EC:4.1.2.47, KEGG_REACTION:R09359] +synonym: "(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity" BROAD [EC:4.1.2.47] +synonym: "(S)-cyanohydrin producing hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-oxynitrilase activity" BROAD [EC:4.1.2.47] +synonym: "(S)-selective hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "hydroxynitrile lyase activity" BROAD [EC:4.1.2.47] +synonym: "oxynitrilase activity" BROAD [EC:4.1.2.47] +xref: EC:4.1.2.47 +xref: KEGG_REACTION:R09359 +xref: MetaCyc:RXN-11732 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0052893 +name: N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide." [MetaCyc:RXN-10465] +synonym: "polyamine oxidase (propane-1,3-diamine-forming) activity" BROAD [EC:1.5.3.14] +xref: EC:1.5.3.14 +xref: MetaCyc:RXN-10465 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052894 +name: norspermine:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide." [MetaCyc:RXN-10464] +synonym: "norspermine oxidase activity" BROAD [EC:1.5.3.16] +xref: EC:1.5.3.16 +xref: MetaCyc:RXN-10464 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052895 +name: N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide." [MetaCyc:POLYAMINE-OXIDASE-RXN] +synonym: "N1-acetylspermine oxidase activity" BROAD [EC:1.5.3.16] +xref: EC:1.5.3.16 +xref: MetaCyc:POLYAMINE-OXIDASE-RXN +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052896 +name: spermidine oxidase (propane-1,3-diamine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2)." [RHEA:25820] +synonym: "polyamine oxidase (propane-1,3-diamine-forming) activity" BROAD [EC:1.5.3.14] +synonym: "spermidine:(acceptor) oxidoreductase activity" BROAD [EC:1.5.3.14] +xref: EC:1.5.3.14 +xref: KEGG_REACTION:R01914 +xref: MetaCyc:RXN-10747 +xref: RHEA:25820 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052897 +name: N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)." [RHEA:25972] +synonym: "N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity" BROAD [EC:1.5.3.15] +xref: EC:1.5.3.15 +xref: KEGG_REACTION:R09075 +xref: MetaCyc:RXN-10463 +xref: RHEA:25972 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052898 +name: N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)." [RHEA:25864] +xref: EC:1.5.3.15 +xref: RHEA:25864 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052899 +name: N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine." [RHEA:25868] +synonym: "N(1)-acetylpolyamine oxidase activity" BROAD [EC:1.5.3.13] +synonym: "polyamine oxidase activity" BROAD [EC:1.5.3.13, EC:1.5.3.17] +xref: EC:1.5.3.13 +xref: MetaCyc:RXN-10460 +xref: RHEA:25868 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052900 +name: spermine oxidase (propane-1,3-diamine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal." [RHEA:25824] +synonym: "polyamine oxidase (propane-1,3-diamine-forming) activity" BROAD [EC:1.5.3.14] +xref: EC:1.5.3.14 +xref: MetaCyc:RXN-6421 +xref: RHEA:25824 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052901 +name: spermine:oxygen oxidoreductase (spermidine-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine." [RHEA:25804] +synonym: "N(1)-acetylpolyamine oxidase activity" BROAD [EC:1.5.3.13] +synonym: "non-specific polyamine oxidase activity" BROAD [EC:1.5.3.17] +synonym: "polyamine oxidase activity" BROAD [EC:1.5.3.13, EC:1.5.3.17] +synonym: "spermine oxidase activity" BROAD [EC:1.5.3.16] +xref: EC:1.5.3.13 +xref: EC:1.5.3.16 +xref: EC:1.5.3.17 +xref: KEGG_REACTION:R09076 +xref: MetaCyc:1.5.3.17-RXN +xref: MetaCyc:RXN-9015 +xref: Reactome:R-HSA-141341 "SMOX-3 oxidises SPN to SPM" +xref: RHEA:25804 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052902 +name: spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine." [RHEA:25808] +synonym: "N(1)-acetylpolyamine oxidase activity" BROAD [EC:1.5.3.13] +synonym: "non-specific polyamine oxidase activity" BROAD [EC:1.5.3.17] +synonym: "polyamine oxidase activity" BROAD [EC:1.5.3.13, EC:1.5.3.17] +xref: EC:1.5.3.13 +xref: EC:1.5.3.17 +xref: KEGG_REACTION:R09077 +xref: MetaCyc:RXN-10461 +xref: MetaCyc:RXN-12089 +xref: RHEA:25808 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052903 +name: N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine." [RHEA:25800] +synonym: "N(1)-acetylpolyamine oxidase activity" BROAD [EC:1.5.3.13] +synonym: "non-specific polyamine oxidase activity" BROAD [EC:1.5.3.17] +synonym: "polyamine oxidase activity" BROAD [EC:1.5.3.13, EC:1.5.3.17] +xref: EC:1.5.3.13 +xref: EC:1.5.3.17 +xref: KEGG_REACTION:R03899 +xref: MetaCyc:RXN-12090 +xref: MetaCyc:RXN-9940 +xref: RHEA:25800 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052904 +name: N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine." [RHEA:25812] +synonym: "N(1)-acetylpolyamine oxidase activity" BROAD [EC:1.5.3.13] +synonym: "non-specific polyamine oxidase activity" BROAD [EC:1.5.3.17] +synonym: "polyamine oxidase activity" BROAD [EC:1.5.3.13, EC:1.5.3.17] +xref: EC:1.5.3.13 +xref: EC:1.5.3.17 +xref: KEGG_REACTION:R09074 +xref: MetaCyc:RXN-12091 +xref: MetaCyc:RXN-9942 +xref: Reactome:R-HSA-141348 "PAO:FAD oxidises NASPM to PTCN" +xref: Reactome:R-HSA-141351 "PAOX:FAD oxidises NASPN to SPM" +xref: RHEA:25812 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0052905 +name: tRNA (guanine(9)-N(1))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.221] +synonym: "tRNA (guanine-N(1)-)-methyltransferase activity" EXACT [EC:2.1.1.221] +synonym: "tRNA m(1)G(9) Mtase activity" EXACT [EC:2.1.1.221] +synonym: "tRNA m(1)G(9)-methyltransferase activity" EXACT [EC:2.1.1.221] +synonym: "tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity" EXACT [EC:2.1.1.221] +synonym: "tRNA(m(1)G(9)/m(1)A(9))Mtase activity" EXACT [EC:2.1.1.221] +xref: EC:2.1.1.221 +xref: MetaCyc:RXN-12459 +is_a: GO:0009019 ! tRNA (guanine-N1-)-methyltransferase activity + +[Term] +id: GO:0052906 +name: tRNA (guanine(37)-N(1))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.228] +synonym: "transfer RNA (m(1)G(37)) methyltransferase activity" EXACT [EC:2.1.1.228] +synonym: "tRNA (m(1)G(37)) methyltransferase activity" EXACT [EC:2.1.1.228] +synonym: "tRNA-(N(1)G37) methyltransferase activity" EXACT [EC:2.1.1.228] +xref: EC:2.1.1.228 +xref: MetaCyc:RXN-12458 +is_a: GO:0009019 ! tRNA (guanine-N1-)-methyltransferase activity + +[Term] +id: GO:0052907 +name: 23S rRNA (adenine(1618)-N(6))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA." [EC:2.1.1.181] +synonym: "M(6)A(1618) activity" BROAD [EC:2.1.1.181] +synonym: "rRNA large subunit methyltransferase F activity" RELATED [EC:2.1.1.181] +xref: EC:2.1.1.181 +xref: KEGG_REACTION:R07232 +xref: MetaCyc:RXN-11596 +is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity + +[Term] +id: GO:0052908 +name: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA." [EC:2.1.1.182] +synonym: "S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity" EXACT [EC:2.1.1.182] +xref: EC:2.1.1.182 +xref: MetaCyc:RXN-11633 +is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity + +[Term] +id: GO:0052909 +name: 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA." [EC:2.1.1.183] +synonym: "M(6)(2)A dimethylase activity" BROAD [EC:2.1.1.183] +xref: EC:2.1.1.183 +xref: MetaCyc:RXN-11634 +is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity + +[Term] +id: GO:0052910 +name: 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA." [EC:2.1.1.184] +synonym: "ermC 23S rRNA methyltransferase activity" RELATED [EC:2.1.1.184] +synonym: "rRNA methyltransferase ermC' activity" RELATED [EC:2.1.1.184] +synonym: "rRNA:m(6)A methyltransferase ermC' activity" RELATED [EC:2.1.1.184] +xref: EC:2.1.1.184 +xref: MetaCyc:RXN-11597 +is_a: GO:0008988 ! rRNA (adenine-N6-)-methyltransferase activity + +[Term] +id: GO:0052911 +name: 23S rRNA (guanine(745)-N(1))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.187] +synonym: "23S rRNA m(1)G(745) methyltransferase activity" EXACT [EC:2.1.1.187] +synonym: "ribosomal ribonucleate guanine 1-methyltransferase activity" BROAD [EC:2.1.1.187] +synonym: "ribosomal RNA(m(1)G)-methylase activity" BROAD [EC:2.1.1.187] +synonym: "rlmA(I) methyltransferase activity" BROAD [EC:2.1.1.187] +synonym: "rRNA(m(1)G)methylase activity" BROAD [EC:2.1.1.187] +synonym: "S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity" BROAD [EC:2.1.1.187] +xref: EC:2.1.1.187 +xref: KEGG_REACTION:R07233 +xref: MetaCyc:RXN-11573 +xref: RHEA:42900 +is_a: GO:0008989 ! rRNA (guanine-N1-)-methyltransferase activity + +[Term] +id: GO:0052912 +name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.188] +synonym: "23S rRNA m(1)G(748) methyltransferase activity" BROAD [EC:2.1.1.188] +xref: EC:2.1.1.188 +xref: KEGG_REACTION:R07233 +xref: MetaCyc:RXN-11599 +xref: RHEA:42904 +is_a: GO:0008989 ! rRNA (guanine-N1-)-methyltransferase activity + +[Term] +id: GO:0052913 +name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.171] +xref: EC:2.1.1.171 +xref: KEGG_REACTION:R07234 +xref: MetaCyc:RXN0-6515 +is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity + +[Term] +id: GO:0052914 +name: 16S rRNA (guanine(1207)-N(2))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.172] +synonym: "M(2)G1207 methyltransferase activity" EXACT [EC:2.1.1.172] +xref: EC:2.1.1.172 +xref: KEGG_REACTION:R07234 +xref: MetaCyc:RXN-11576 +is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity + +[Term] +id: GO:0052915 +name: 23S rRNA (guanine(2445)-N(2))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.173] +xref: EC:2.1.1.173 +xref: KEGG_REACTION:R07234 +xref: MetaCyc:RXN-11574 +is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity + +[Term] +id: GO:0052916 +name: 23S rRNA (guanine(1835)-N(2))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine." [EC:2.1.1.174] +xref: EC:2.1.1.174 +xref: KEGG_REACTION:R07234 +xref: MetaCyc:RXN-11635 +is_a: GO:0008990 ! rRNA (guanine-N2-)-methyltransferase activity + +[Term] +id: GO:0052917 +name: dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.260, RHEA:29535] +synonym: "dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl alpha-6-mannosyltransferase activity" EXACT [EC:2.4.1.260] +synonym: "dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity" EXACT [EC:2.4.1.260] +xref: EC:2.4.1.260 +xref: KEGG_REACTION:R06260 +xref: MetaCyc:RXN-5468 +xref: RHEA:29535 +is_a: GO:0000009 ! alpha-1,6-mannosyltransferase activity + +[Term] +id: GO:0052918 +name: dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.261, RHEA:29539] +xref: EC:2.4.1.261 +xref: KEGG_REACTION:R06261 +xref: MetaCyc:RXN-5469 +xref: RHEA:29539 +is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity + +[Term] +id: GO:0052919 +name: aliphatic (R)-hydroxynitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide." [EC:4.1.2.46] +synonym: "(R)-HNL activity" BROAD [EC:4.1.2.46] +synonym: "(R)-hydroxynitrile lyase activity" BROAD [EC:4.1.2.46] +synonym: "(R)-oxynitrilase activity" BROAD [EC:4.1.2.46] +xref: EC:4.1.2.46 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0052920 +name: (2R)-2-hydroxy-2-methylbutanenitrile lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide." [EC:4.1.2.46] +xref: EC:4.1.2.46 +xref: KEGG_REACTION:R09358 +xref: MetaCyc:RXN-11733 +xref: RHEA:28170 +is_a: GO:0052919 ! aliphatic (R)-hydroxynitrile lyase activity + +[Term] +id: GO:0052921 +name: acetone-cyanohydrin acetone-lyase (cyanide-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone." [KEGG_REACTION:R01553, MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN] +xref: EC:4.1.2.46 +xref: KEGG_REACTION:R01553 +xref: MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN +is_a: GO:0052919 ! aliphatic (R)-hydroxynitrile lyase activity + +[Term] +id: GO:0052922 +name: hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate." [RHEA:27555] +synonym: "(all-E) hexaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.82] +synonym: "(all-trans)-hexaprenyl-diphosphate synthase activity" BROAD [EC:2.5.1.82] +synonym: "hexaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.82] +synonym: "hexaprenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.82] +xref: EC:2.5.1.82 +xref: KEGG_REACTION:R09246 +xref: MetaCyc:RXN-11485 +xref: RHEA:27555 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0052923 +name: all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate." [EC:2.5.1.84, RHEA:27563] +synonym: "nonaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.84] +synonym: "solanesyl diphosphate synthetase activity" BROAD [EC:2.5.1.84] +synonym: "solanesyl-diphosphate synthase activity" BROAD [EC:2.5.1.84] +synonym: "solPP synthase activity" BROAD [EC:2.5.1.84] +synonym: "SPP synthase activity" BROAD [EC:2.5.1.84] +synonym: "SPP-synthase activity" BROAD [EC:2.5.1.84] +xref: EC:2.5.1.84 +xref: KEGG_REACTION:R09250 +xref: MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN +xref: RHEA:27563 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0052924 +name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity +namespace: molecular_function +def: "Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate." [EC:2.5.1.85] +synonym: "nonaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.85] +synonym: "solanesyl diphosphate synthase activity" BROAD [EC:2.5.1.85] +synonym: "solanesyl diphosphate synthetase activity" BROAD [EC:2.5.1.85] +xref: EC:2.5.1.85 +xref: KEGG_REACTION:R09251 +xref: MetaCyc:RXN-11486 +xref: RHEA:27594 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0052925 +name: dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [RHEA:29527] +synonym: "dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity" EXACT [EC:2.4.1.258] +synonym: "man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity" EXACT [EC:2.4.1.258] +xref: EC:2.4.1.258 +xref: KEGG_REACTION:R06258 +xref: MetaCyc:RXN-5466 +xref: RHEA:29527 +is_a: GO:0000033 ! alpha-1,3-mannosyltransferase activity + +[Term] +id: GO:0052926 +name: dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate." [EC:2.4.1.259, RHEA:29531] +synonym: "dolichylphosphomannose-dependent ALG9 mannosyltransferase activity" RELATED [EC:2.4.1.259] +xref: EC:2.4.1.259 +xref: KEGG_REACTION:R06259 +xref: MetaCyc:RXN-5467 +xref: RHEA:29531 +is_a: GO:0000026 ! alpha-1,2-mannosyltransferase activity + +[Term] +id: GO:0052927 +name: CTP:tRNA cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate." [KEGG_REACTION:R09383] +xref: EC:2.7.7.72 +xref: KEGG_REACTION:R09383 +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0052928 +name: CTP:3'-cytidine-tRNA cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate." [KEGG_REACTION:R09384] +xref: EC:2.7.7.72 +xref: KEGG_REACTION:R09384 +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0052929 +name: ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate." [KEGG_REACTION:R09386] +synonym: "ATP:3'-CC-tRNA adenylyltransferase activity" EXACT [] +synonym: "ATP:tRNA adenylyltransferase activity" BROAD [] +xref: EC:2.7.7.72 +xref: KEGG_REACTION:R09386 +is_a: GO:0004810 ! tRNA adenylyltransferase activity + +[Term] +id: GO:0052930 +name: methanol ferricytochrome-c oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: methanol + 2 ferricytochrome c = formaldehyde + 2 ferrocytochrome c + 2 H+." [KEGG_REACTION:R01146] +synonym: "methanol dehydrogenase (cytochrome c) activity" BROAD [EC:1.1.2.7] +synonym: "methanol dehydrogenase activity" BROAD [EC:1.1.2.7] +xref: EC:1.1.2.7 +xref: KEGG_REACTION:R01146 +xref: MetaCyc:RXN-2861 +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0052931 +name: ethanol cytochrome-c oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethanol + 2 cytochrome c(L) = acetaldehyde + 2 reduced cytochrome c(L) + 2 H+." [KEGG_REACTION:R09127] +synonym: "ethanol dehydrogenase (cytochrome c) activity" BROAD [EC:1.1.2.7] +synonym: "ethanol dehydrogenase activity" BROAD [EC:1.1.2.7] +xref: EC:1.1.2.7 +xref: KEGG_REACTION:R09127 +is_a: GO:0052933 ! alcohol dehydrogenase (cytochrome c(L)) activity + +[Term] +id: GO:0052932 +name: 2-chloroethanol cytochrome-c oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c(L) = chloroacetaldehyde + 2 reduced cytochrome c(L)." [KEGG_REACTION:R09128] +synonym: "2-chloroethanol dehydrogenase (cytochrome c) activity" BROAD [EC:1.1.2.7] +synonym: "2-chloroethanol dehydrogenase activity" BROAD [EC:1.1.2.7] +xref: EC:1.1.2.7 +xref: KEGG_REACTION:R09128 +is_a: GO:0052933 ! alcohol dehydrogenase (cytochrome c(L)) activity + +[Term] +id: GO:0052933 +name: alcohol dehydrogenase (cytochrome c(L)) activity +namespace: molecular_function +def: "Catalysis of the reaction: primary alcohol + 2 cytochrome c(L) = 2 reduced cytochrome c(L) + an aldehyde + 2 H+." [EC:1.1.2.7] +synonym: "alcohol:cytochrome c(L) oxidoreductase activity" EXACT systematic_synonym [EC:1.1.2.7] +xref: EC:1.1.2.7 +xref: MetaCyc:RXN-11332 +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0052934 +name: alcohol dehydrogenase (cytochrome c) activity +namespace: molecular_function +def: "Catalysis of the reaction: primary alcohol + 2 cytochrome c = 2 reduced cytochrome c + an aldehyde + 2 H+." [EC:1.1.2.8] +synonym: "alcohol:cytochrome c oxidoreductase activity" EXACT systematic_synonym [EC:1.1.2.8] +synonym: "quinoprotein alcohol dehydrogenase activity" RELATED [EC:1.1.2.8] +xref: EC:1.1.2.8 +xref: MetaCyc:RXN-11333 +is_a: GO:0016898 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor + +[Term] +id: GO:0052935 +name: ethanol:cytochrome c oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethanol + 2 cytochrome c = 2 reduced cytochrome c + acetaldehyde." [KEGG_REACTION:R05198] +synonym: "ethanol dehydrogenase (cytochrome c) activity" EXACT [EC:1.1.2.8] +xref: EC:1.1.2.8 +xref: KEGG_REACTION:R05198 +xref: RHEA:51020 +is_a: GO:0052934 ! alcohol dehydrogenase (cytochrome c) activity + +[Term] +id: GO:0052936 +name: 2-chloroethanol:cytochrome c oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c = chloroacetaldehyde + 2 reduced cytochrome c." [KEGG_REACTION:R05285] +xref: KEGG_REACTION:R05285 +xref: RHEA:55947 +is_a: GO:0052934 ! alcohol dehydrogenase (cytochrome c) activity + +[Term] +id: GO:0055001 +name: muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0042692 ! muscle cell differentiation + +[Term] +id: GO:0055002 +name: striated muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol] +is_a: GO:0055001 ! muscle cell development +relationship: part_of GO:0051146 ! striated muscle cell differentiation + +[Term] +id: GO:0055003 +name: cardiac myofibril assembly +namespace: biological_process +def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] +synonym: "cardiac myofibril development" EXACT [] +synonym: "cardiac myofibril morphogenesis" EXACT [] +synonym: "heart myofibril assembly" RELATED [] +is_a: GO:0030239 ! myofibril assembly +relationship: part_of GO:0055013 ! cardiac muscle cell development + +[Term] +id: GO:0055004 +name: atrial cardiac myofibril assembly +namespace: biological_process +def: "The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] +synonym: "atrial cardiac myofibril development" EXACT [GOC:dph] +synonym: "atrial heart myofibril development" EXACT [] +is_a: GO:0055003 ! cardiac myofibril assembly +relationship: part_of GO:0055014 ! atrial cardiac muscle cell development + +[Term] +id: GO:0055005 +name: ventricular cardiac myofibril assembly +namespace: biological_process +def: "The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] +synonym: "ventricular cardiac myofibril development" RELATED [] +synonym: "ventricular heart myofibril development" EXACT [] +is_a: GO:0055003 ! cardiac myofibril assembly +relationship: part_of GO:0055015 ! ventricular cardiac muscle cell development + +[Term] +id: GO:0055006 +name: cardiac cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol] +synonym: "cardiocyte development" EXACT [GOC:dph] +synonym: "heart cell development" RELATED [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0035051 ! cardiocyte differentiation + +[Term] +id: GO:0055007 +name: cardiac muscle cell differentiation +namespace: biological_process +def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart] +synonym: "cardiomyocyte differentiation" EXACT [] +synonym: "heart muscle cell differentiation" RELATED [] +is_a: GO:0035051 ! cardiocyte differentiation +is_a: GO:0051146 ! striated muscle cell differentiation +relationship: part_of GO:0048738 ! cardiac muscle tissue development + +[Term] +id: GO:0055008 +name: cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol] +synonym: "heart muscle morphogenesis" EXACT [] +synonym: "myocardium morphogenesis" BROAD [GOC:mtg_heart] +is_a: GO:0060415 ! muscle tissue morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0048738 ! cardiac muscle tissue development + +[Term] +id: GO:0055009 +name: atrial cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol] +synonym: "atrial heart muscle morphogenesis" EXACT [] +synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart] +synonym: "cardiac atrium muscle morphogenesis" EXACT [] +is_a: GO:0055008 ! cardiac muscle tissue morphogenesis +relationship: part_of GO:0003209 ! cardiac atrium morphogenesis +relationship: part_of GO:0003228 ! atrial cardiac muscle tissue development + +[Term] +id: GO:0055010 +name: ventricular cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol] +synonym: "cardiac ventricle muscle morphogenesis" EXACT [] +synonym: "ventricular heart muscle morphogenesis" EXACT [] +is_a: GO:0055008 ! cardiac muscle tissue morphogenesis +relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis +relationship: part_of GO:0003229 ! ventricular cardiac muscle tissue development + +[Term] +id: GO:0055011 +name: atrial cardiac muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ." [GOC:devbiol, GOC:mtg_heart] +synonym: "atrial cardiomyocyte differentiation" EXACT [] +synonym: "atrial heart muscle cell differentiation" EXACT [] +is_a: GO:0055007 ! cardiac muscle cell differentiation + +[Term] +id: GO:0055012 +name: ventricular cardiac muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ." [GOC:devbiol, GOC:mtg_heart] +synonym: "ventricular cardiomyocyte differentiation" EXACT [] +synonym: "ventricular heart muscle cell differentiation" EXACT [] +is_a: GO:0055007 ! cardiac muscle cell differentiation + +[Term] +id: GO:0055013 +name: cardiac muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart] +synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle] +synonym: "heart muscle cell development" EXACT [] +is_a: GO:0055002 ! striated muscle cell development +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0055007 ! cardiac muscle cell differentiation + +[Term] +id: GO:0055014 +name: atrial cardiac muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ." [GOC:devbiol] +synonym: "atrial cardiomyocyte development" EXACT [] +synonym: "atrial heart muscle development" EXACT [] +is_a: GO:0055013 ! cardiac muscle cell development +relationship: part_of GO:0055011 ! atrial cardiac muscle cell differentiation + +[Term] +id: GO:0055015 +name: ventricular cardiac muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ." [GOC:devbiol, GOC:mtg_muscle] +synonym: "ventricular cardiomyocyte development" EXACT [] +synonym: "ventricular heart muscle cell development" EXACT [] +is_a: GO:0055013 ! cardiac muscle cell development +relationship: part_of GO:0055012 ! ventricular cardiac muscle cell differentiation + +[Term] +id: GO:0055016 +name: hypochord development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta." [GOC:devbiol, GOC:lb] +synonym: "subnotochordal rod development" EXACT [] +is_a: GO:0009888 ! tissue development +is_a: GO:0048568 ! embryonic organ development + +[Term] +id: GO:0055017 +name: cardiac muscle tissue growth +namespace: biological_process +def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol] +synonym: "heart muscle growth" EXACT [] +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0048738 ! cardiac muscle tissue development +relationship: part_of GO:0060419 ! heart growth + +[Term] +id: GO:0055018 +name: regulation of cardiac muscle fiber development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] +synonym: "regulation of cardiac muscle fibre development" EXACT [] +synonym: "regulation of heart muscle fiber development" EXACT [] +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048739 ! cardiac muscle fiber development +relationship: regulates GO:0048739 ! cardiac muscle fiber development + +[Term] +id: GO:0055019 +name: negative regulation of cardiac muscle fiber development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] +synonym: "down regulation of cardiac muscle fiber development" EXACT [] +synonym: "down-regulation of cardiac muscle fiber development" EXACT [] +synonym: "downregulation of cardiac muscle fiber development" EXACT [] +synonym: "inhibition of cardiac muscle fiber development" NARROW [] +synonym: "negative regulation of cardiac muscle fibre development" EXACT [] +synonym: "negative regulation of heart muscle fiber development" RELATED [] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0055018 ! regulation of cardiac muscle fiber development +is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048739 ! cardiac muscle fiber development +relationship: negatively_regulates GO:0048739 ! cardiac muscle fiber development + +[Term] +id: GO:0055020 +name: positive regulation of cardiac muscle fiber development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] +synonym: "activation of cardiac muscle fiber development" NARROW [] +synonym: "positive regulation of cardiac muscle fibre development" EXACT [] +synonym: "positive regulation of heart muscle fiber development" EXACT [] +synonym: "stimulation of cardiac muscle fiber development" NARROW [] +synonym: "up regulation of cardiac muscle fiber development" EXACT [] +synonym: "up-regulation of cardiac muscle fiber development" EXACT [] +synonym: "upregulation of cardiac muscle fiber development" EXACT [] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0055018 ! regulation of cardiac muscle fiber development +is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048739 ! cardiac muscle fiber development +relationship: positively_regulates GO:0048739 ! cardiac muscle fiber development + +[Term] +id: GO:0055021 +name: regulation of cardiac muscle tissue growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk] +is_a: GO:0055024 ! regulation of cardiac muscle tissue development +is_a: GO:0060420 ! regulation of heart growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055017 ! cardiac muscle tissue growth +relationship: regulates GO:0055017 ! cardiac muscle tissue growth + +[Term] +id: GO:0055022 +name: negative regulation of cardiac muscle tissue growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk] +synonym: "down regulation of cardiac muscle growth" EXACT [] +synonym: "down-regulation of cardiac muscle growth" EXACT [] +synonym: "downregulation of cardiac muscle growth" EXACT [] +synonym: "inhibition of cardiac muscle growth" NARROW [] +synonym: "negative regulation of heart muscle growth" RELATED [] +is_a: GO:0055021 ! regulation of cardiac muscle tissue growth +is_a: GO:0055026 ! negative regulation of cardiac muscle tissue development +is_a: GO:0061117 ! negative regulation of heart growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055017 ! cardiac muscle tissue growth +relationship: negatively_regulates GO:0055017 ! cardiac muscle tissue growth + +[Term] +id: GO:0055023 +name: positive regulation of cardiac muscle tissue growth +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk] +synonym: "activation of cardiac muscle growth" NARROW [] +synonym: "positive regulation of heart muscle growth" EXACT [] +synonym: "stimulation of cardiac muscle growth" NARROW [] +synonym: "up regulation of cardiac muscle growth" EXACT [] +synonym: "up-regulation of cardiac muscle growth" EXACT [] +synonym: "upregulation of cardiac muscle growth" EXACT [] +is_a: GO:0055021 ! regulation of cardiac muscle tissue growth +is_a: GO:0055025 ! positive regulation of cardiac muscle tissue development +is_a: GO:0060421 ! positive regulation of heart growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055017 ! cardiac muscle tissue growth +relationship: positively_regulates GO:0055017 ! cardiac muscle tissue growth + +[Term] +id: GO:0055024 +name: regulation of cardiac muscle tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] +synonym: "regulation of heart muscle development" EXACT [] +is_a: GO:0016202 ! regulation of striated muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048738 ! cardiac muscle tissue development +relationship: regulates GO:0048738 ! cardiac muscle tissue development + +[Term] +id: GO:0055025 +name: positive regulation of cardiac muscle tissue development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] +synonym: "activation of cardiac muscle development" NARROW [] +synonym: "positive regulation of heart muscle development" EXACT [] +synonym: "stimulation of cardiac muscle development" NARROW [] +synonym: "up regulation of cardiac muscle development" EXACT [] +synonym: "up-regulation of cardiac muscle development" EXACT [] +synonym: "upregulation of cardiac muscle development" EXACT [] +is_a: GO:0045844 ! positive regulation of striated muscle tissue development +is_a: GO:0055024 ! regulation of cardiac muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048738 ! cardiac muscle tissue development +relationship: positively_regulates GO:0048738 ! cardiac muscle tissue development + +[Term] +id: GO:0055026 +name: negative regulation of cardiac muscle tissue development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] +synonym: "down regulation of cardiac muscle development" EXACT [] +synonym: "down-regulation of cardiac muscle development" EXACT [] +synonym: "downregulation of cardiac muscle development" EXACT [] +synonym: "inhibition of cardiac muscle development" NARROW [] +synonym: "negative regulation of heart muscle development" EXACT [] +is_a: GO:0045843 ! negative regulation of striated muscle tissue development +is_a: GO:0055024 ! regulation of cardiac muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048738 ! cardiac muscle tissue development +relationship: negatively_regulates GO:0048738 ! cardiac muscle tissue development + +[Term] +id: GO:0055028 +name: cortical microtubule +namespace: cellular_component +def: "Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol." [GOC:mtg_sensu] +is_a: GO:0005881 ! cytoplasmic microtubule +relationship: part_of GO:0030981 ! cortical microtubule cytoskeleton + +[Term] +id: GO:0055029 +name: nuclear DNA-directed RNA polymerase complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity." [GOC:mtg_sensu] +is_a: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: GO:0000428 ! DNA-directed RNA polymerase complex +intersection_of: part_of GO:0005634 ! nucleus +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0055031 +name: gamma-tubulin large complex, equatorial microtubule organizing center +namespace: cellular_component +def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at equatorial microtubule organizing centers." [GOC:mtg_sensu] +synonym: "gamma-tubulin large complex, eMTOC" EXACT [] +synonym: "gamma-tubulin large complex, equatorial microtubule organizing centre" EXACT [] +is_a: GO:0000931 ! gamma-tubulin large complex +intersection_of: GO:0000931 ! gamma-tubulin large complex +intersection_of: part_of GO:0000923 ! equatorial microtubule organizing center +relationship: part_of GO:0000923 ! equatorial microtubule organizing center + +[Term] +id: GO:0055032 +name: gamma-tubulin large complex, spindle pole body +namespace: cellular_component +def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body." [GOC:mtg_sensu] +is_a: GO:0000931 ! gamma-tubulin large complex +intersection_of: GO:0000931 ! gamma-tubulin large complex +intersection_of: part_of GO:0005816 ! spindle pole body +relationship: part_of GO:0005816 ! spindle pole body + +[Term] +id: GO:0055033 +name: gamma-tubulin large complex, interphase microtubule organizing center +namespace: cellular_component +def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at interphase microtubule organizing centers." [GOC:mtg_sensu] +synonym: "gamma-tubulin large complex, iMTOC" EXACT [] +synonym: "gamma-tubulin large complex, interphase microtubule organizing centre" EXACT [] +is_a: GO:0000931 ! gamma-tubulin large complex +intersection_of: GO:0000931 ! gamma-tubulin large complex +intersection_of: part_of GO:0031021 ! interphase microtubule organizing center +relationship: part_of GO:0031021 ! interphase microtubule organizing center + +[Term] +id: GO:0055034 +name: Bolwig's organ development +namespace: biological_process +def: "The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain." [GOC:mtg_sensu] +is_a: GO:0001654 ! eye development + +[Term] +id: GO:0055035 +name: plastid thylakoid membrane +namespace: cellular_component +def: "The lipid bilayer membrane of any thylakoid within a plastid." [GOC:jid, GOC:rph] +is_a: GO:0042651 ! thylakoid membrane +relationship: part_of GO:0031976 ! plastid thylakoid + +[Term] +id: GO:0055036 +name: virion membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a virion." [GOC:jid, GOC:rph, PMID:213106] +subset: goslim_chembl +is_a: GO:0016020 ! membrane +is_a: GO:0044423 ! virion part + +[Term] +id: GO:0055037 +name: recycling endosome +namespace: cellular_component +def: "An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane." [GOC:dph, GOC:jid, GOC:kmv, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101, PMID:21556374, PMID:21562044] +synonym: "endosomal recycling compartment" EXACT [PMID:20820847] +synonym: "endosome recycling compartment" RELATED [GOC:dph, PMID:12370264] +synonym: "ERC" RELATED [GOC:dph, PMID:1237064] +is_a: GO:0005768 ! endosome + +[Term] +id: GO:0055038 +name: recycling endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a recycling endosome." [GOC:jid, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101] +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0055037 ! recycling endosome + +[Term] +id: GO:0055039 +name: trichocyst +namespace: cellular_component +def: "A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft." [GOC:jid, GOC:rph, http://www.iscid.org/encyclopedia/, PMID:3667715] +xref: Wikipedia:Trichocyst +is_a: GO:0043264 ! extracellular non-membrane-bounded organelle + +[Term] +id: GO:0055040 +name: periplasmic flagellum +namespace: cellular_component +def: "Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella." [GOC:jid, GOC:rph, PMID:15175283, PMID:1624463] +is_a: GO:0009288 ! bacterial-type flagellum +relationship: part_of GO:0042597 ! periplasmic space + +[Term] +id: GO:0055041 +name: cyclopentanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH." [EC:1.1.1.163, RHEA:11728] +synonym: "cyclopentanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.163] +synonym: "cyclopentanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.163] +xref: EC:1.1.1.163 +xref: KEGG_REACTION:R02553 +xref: MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN +xref: RHEA:11728 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0055042 +name: 5-valerolactone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate." [GOC:jid, GOC:mlg] +is_a: GO:0046573 ! lactonohydrolase activity + +[Term] +id: GO:0055043 +name: 5-oxovalerate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+." [GOC:jid, GOC:mlg] +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0055044 +name: symplast +namespace: cellular_component +def: "The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata." [GOC:mtg_sensu] +subset: goslim_pir +xref: Wikipedia:Symplast +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0055045 +name: antipodal cell degeneration +namespace: biological_process +def: "The process in which the antipodal cells undergo programmed cell death." [GOC:mtg_plant] +is_a: GO:0010623 ! programmed cell death involved in cell development +relationship: part_of GO:0009561 ! megagametogenesis + +[Term] +id: GO:0055046 +name: microgametogenesis +namespace: biological_process +def: "The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure." [GOC:mtg_plant] +synonym: "pollen development from the microspore" EXACT systematic_synonym [] +xref: Wikipedia:Microgametogenesis +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0009555 ! pollen development + +[Term] +id: GO:0055047 +name: generative cell mitosis +namespace: biological_process +def: "The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells." [GOC:mtg_plant] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0140014 ! mitotic nuclear division +relationship: part_of GO:0048232 ! male gamete generation + +[Term] +id: GO:0055048 +name: anastral spindle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins." [GOC:expert_rg, GOC:mtg_sensu, GOC:tb, PMID:15034926] +is_a: GO:0051225 ! spindle assembly + +[Term] +id: GO:0055049 +name: astral spindle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes." [GOC:tb] +is_a: GO:0051225 ! spindle assembly + +[Term] +id: GO:0055050 +name: astral spindle assembly involved in male meiosis +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells." [GOC:tb] +is_a: GO:0007053 ! spindle assembly involved in male meiosis +is_a: GO:0055049 ! astral spindle assembly +intersection_of: GO:0055049 ! astral spindle assembly +intersection_of: part_of GO:0007140 ! male meiotic nuclear division + +[Term] +id: GO:0055051 +name: ATP-binding cassette (ABC) transporter complex, integrated substrate binding +namespace: cellular_component +def: "A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex + +[Term] +id: GO:0055052 +name: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing +namespace: cellular_component +def: "A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex + +[Term] +id: GO:0055053 +name: mannose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+." [GOC:ct] +synonym: "mannose:hydrogen symporter activity" EXACT [] +is_a: GO:0009679 ! hexose:proton symporter activity +is_a: GO:0015578 ! mannose transmembrane transporter activity + +[Term] +id: GO:0055054 +name: fructose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+." [GOC:ct] +synonym: "fructose:hydrogen symporter activity" EXACT [] +is_a: GO:0005353 ! fructose transmembrane transporter activity +is_a: GO:0009679 ! hexose:proton symporter activity + +[Term] +id: GO:0055055 +name: D-glucose:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose." [GOC:ct] +synonym: "D-glucose:hydrogen symporter activity" EXACT [] +is_a: GO:0005356 ! glucose:proton symporter activity +is_a: GO:0055056 ! D-glucose transmembrane transporter activity + +[Term] +id: GO:0055056 +name: D-glucose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:jid, GOC:jsg, GOC:mah] +xref: Reactome:R-HSA-429094 "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-450095 "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region" +xref: Reactome:R-HSA-5339524 "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-5632804 "SLC2A1 tetramer does not transport Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-5632871 "Defective SLC2A10 does not transport Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-8981553 "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-8981564 "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-8981570 "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol" +xref: Reactome:R-HSA-8981574 "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol" +is_a: GO:0005355 ! glucose transmembrane transporter activity + +[Term] +id: GO:0055057 +name: neuroblast division +namespace: biological_process +def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] +synonym: "neuroblast cell division" EXACT [] +is_a: GO:0017145 ! stem cell division +relationship: part_of GO:0007405 ! neuroblast proliferation + +[Term] +id: GO:0055058 +name: symmetric neuroblast division +namespace: biological_process +def: "The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells." [GOC:dph] +is_a: GO:0055057 ! neuroblast division + +[Term] +id: GO:0055059 +name: asymmetric neuroblast division +namespace: biological_process +def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] +is_a: GO:0045165 ! cell fate commitment +is_a: GO:0055057 ! neuroblast division +is_a: GO:0098722 ! asymmetric stem cell division + +[Term] +id: GO:0055060 +name: asymmetric neuroblast division resulting in ganglion mother cell formation +namespace: biological_process +def: "Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell." [GOC:dph] +is_a: GO:0014017 ! neuroblast fate commitment +is_a: GO:0055059 ! asymmetric neuroblast division + +[Term] +id: GO:0055061 +name: obsolete di-, tri-valent inorganic anion homeostasis +namespace: biological_process +def: "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +comment: This term was made obsolete because it has been split. +synonym: "di-, tri-valent inorganic anion homeostasis" EXACT [] +is_obsolete: true +consider: GO:0072505 +consider: GO:0072506 + +[Term] +id: GO:0055062 +name: phosphate ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell." [GOC:jid, GOC:mah] +is_a: GO:0055083 ! monovalent inorganic anion homeostasis +is_a: GO:0072505 ! divalent inorganic anion homeostasis +is_a: GO:0072506 ! trivalent inorganic anion homeostasis + +[Term] +id: GO:0055063 +name: sulfate ion homeostasis +namespace: biological_process +alt_id: GO:0080174 +def: "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." [GOC:jid, GOC:mah] +synonym: "sulfate homeostasis" EXACT [] +synonym: "sulphate ion homeostasis" EXACT [] +is_a: GO:0072505 ! divalent inorganic anion homeostasis + +[Term] +id: GO:0055064 +name: chloride ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell." [GOC:jid, GOC:mah] +is_a: GO:0055083 ! monovalent inorganic anion homeostasis + +[Term] +id: GO:0055065 +name: metal ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +subset: goslim_pombe +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis + +[Term] +id: GO:0055066 +name: obsolete di-, tri-valent inorganic cation homeostasis +namespace: biological_process +def: "OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah] +comment: This term was made obsolete because it has been split. +synonym: "di-, tri-valent inorganic cation homeostasis" EXACT [] +is_obsolete: true +consider: GO:0072507 +consider: GO:0072508 + +[Term] +id: GO:0055067 +name: monovalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis + +[Term] +id: GO:0055068 +name: cobalt ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +synonym: "cobalt homeostasis" BROAD [] +is_a: GO:0055076 ! transition metal ion homeostasis + +[Term] +id: GO:0055069 +name: zinc ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +synonym: "zinc homeostasis" BROAD [] +is_a: GO:0055076 ! transition metal ion homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis + +[Term] +id: GO:0055070 +name: copper ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +synonym: "copper homeostasis" BROAD [] +is_a: GO:0055076 ! transition metal ion homeostasis + +[Term] +id: GO:0055071 +name: manganese ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell." [GOC:jid, GOC:mah] +synonym: "manganese homeostasis" BROAD [] +is_a: GO:0055076 ! transition metal ion homeostasis + +[Term] +id: GO:0055072 +name: iron ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +synonym: "iron homeostasis" BROAD [] +is_a: GO:0055076 ! transition metal ion homeostasis + +[Term] +id: GO:0055073 +name: cadmium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +synonym: "cadmium homeostasis" EXACT [] +is_a: GO:0055076 ! transition metal ion homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis + +[Term] +id: GO:0055074 +name: calcium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah] +synonym: "regulation of calcium ion concentration" EXACT [] +is_a: GO:0055065 ! metal ion homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis + +[Term] +id: GO:0055075 +name: potassium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell." [GOC:jid, GOC:mah] +is_a: GO:0055065 ! metal ion homeostasis +is_a: GO:0055067 ! monovalent inorganic cation homeostasis + +[Term] +id: GO:0055076 +name: transition metal ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [GOC:jid, GOC:mah, ISBN:0198506732] +is_a: GO:0055065 ! metal ion homeostasis + +[Term] +id: GO:0055077 +name: gap junction hemi-channel activity +namespace: molecular_function +def: "A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction." [GOC:dgh] +synonym: "connexon channel activity" EXACT [] +is_a: GO:0022829 ! wide pore channel activity +relationship: part_of GO:0005243 ! gap junction channel activity + +[Term] +id: GO:0055078 +name: sodium ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +is_a: GO:0055065 ! metal ion homeostasis +is_a: GO:0055067 ! monovalent inorganic cation homeostasis + +[Term] +id: GO:0055079 +name: aluminum ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell." [GOC:jid, GOC:lr, GOC:mah] +synonym: "aluminium ion homeostasis" EXACT [GOC:mah] +is_a: GO:0055065 ! metal ion homeostasis + +[Term] +id: GO:0055080 +name: cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cations within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah] +is_a: GO:0050801 ! ion homeostasis + +[Term] +id: GO:0055081 +name: anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of anions within an organism or cell." [GOC:ceb, GOC:jid, GOC:mah] +is_a: GO:0050801 ! ion homeostasis + +[Term] +id: GO:0055082 +name: cellular chemical homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell." [GOC:isa_complete, GOC:jid] +is_a: GO:0019725 ! cellular homeostasis +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0055083 +name: monovalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell." [GOC:ai, GOC:jid, GOC:mah] +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis + +[Term] +id: GO:0055085 +name: transmembrane transport +namespace: biological_process +alt_id: GO:0090662 +def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid] +comment: Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes. +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pombe +subset: goslim_yeast +synonym: "ATP hydrolysis coupled transmembrane transport" NARROW [] +synonym: "membrane transport" EXACT [] +is_a: GO:0006810 ! transport +is_a: GO:0009987 ! cellular process +created_by: tb +creation_date: 2015-10-21T13:22:47Z + +[Term] +id: GO:0055086 +name: nucleobase-containing small molecule metabolic process +namespace: biological_process +def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] +subset: goslim_drosophila +subset: goslim_pombe +subset: goslim_yeast +synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] +synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0055087 +name: Ski complex +namespace: cellular_component +def: "A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p." [GOC:mcc, PMID:10744028, PMID:15703439, PMID:16043509, PMID:18042677] +xref: Wikipedia:Ski_complex +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0055088 +name: lipid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell." [GOC:BHF, GOC:rl] +is_a: GO:0048878 ! chemical homeostasis + +[Term] +id: GO:0055089 +name: fatty acid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell." [GOC:BHF, GOC:rl] +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0055090 +name: acylglycerol homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell." [GOC:BHF, GOC:rl] +synonym: "glyceride homeostasis" EXACT [] +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0055091 +name: phospholipid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell." [GOC:BHF, GOC:rl] +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0055092 +name: sterol homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sterol within an organism or cell." [GOC:BHF, GOC:rl] +is_a: GO:0055088 ! lipid homeostasis + +[Term] +id: GO:0055093 +name: response to hyperoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension." [GOC:kmv] +synonym: "response to hyperoxic stress" EXACT [] +synonym: "response to increased oxygen tension" EXACT [] +is_a: GO:0006950 ! response to stress +is_a: GO:0036296 ! response to increased oxygen levels + +[Term] +id: GO:0055094 +name: response to lipoprotein particle +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus." [GOC:BHF, GOC:rl] +synonym: "response to lipoprotein particle stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0010243 ! response to organonitrogen compound + +[Term] +id: GO:0055095 +name: lipoprotein particle mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of a lipoprotein particle." [GOC:BHF, GOC:rl] +synonym: "lipoprotein mediated signalling" EXACT [] +synonym: "lipoprotein particle mediated signal transduction" EXACT [GOC:signaling] +synonym: "lipoprotein particle-mediated signaling" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0071402 ! cellular response to lipoprotein particle stimulus + +[Term] +id: GO:0055096 +name: low-density lipoprotein particle mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of low-density lipoprotein particle." [GOC:BHF, GOC:rl, PMID:16013438] +synonym: "low-density lipoprotein mediated signalling" EXACT [] +synonym: "low-density lipoprotein particle mediated signal transduction" EXACT [GOC:signaling] +synonym: "low-density lipoprotein particle-mediated signaling" EXACT [] +is_a: GO:0055095 ! lipoprotein particle mediated signaling +relationship: part_of GO:0071404 ! cellular response to low-density lipoprotein particle stimulus + +[Term] +id: GO:0055097 +name: high density lipoprotein particle mediated signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of high density lipoprotein particle." [GOC:BHF, GOC:rl] +synonym: "high density lipoprotein mediated signalling" EXACT [] +synonym: "high density lipoprotein particle mediated signal transduction" EXACT [GOC:signaling] +synonym: "high density lipoprotein particle-mediated signaling" EXACT [] +is_a: GO:0055095 ! lipoprotein particle mediated signaling +relationship: part_of GO:0071403 ! cellular response to high density lipoprotein particle stimulus + +[Term] +id: GO:0055100 +name: adiponectin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism." [GOC:BHF, GOC:rl, PMID:15210937] +is_a: GO:0005515 ! protein binding +is_a: GO:0042562 ! hormone binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0055101 +name: obsolete glycerophospholipase inhibitor activity +namespace: molecular_function +def: "OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai, GOC:BHF, GOC:rl] +comment: This term was made obsolete because it refers to a non-existent molecular function term, 'glycerophosphate activity', which also cannot be found in the literature. +synonym: "glycerophospholipase inhibitor activity" EXACT [] +is_obsolete: true + +[Term] +id: GO:0055102 +name: lipase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:BHF, GOC:rl] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0016298 ! lipase activity + +[Term] +id: GO:0055103 +name: ligase regulator activity +namespace: molecular_function +def: "Modulates the activity of a ligase." [GOC:BHF, GOC:rl] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0016874 ! ligase activity + +[Term] +id: GO:0055104 +name: ligase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a ligase." [GOC:BHF, GOC:rl] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0016874 ! ligase activity + +[Term] +id: GO:0055105 +name: ubiquitin-protein transferase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a ubiquitin-protein transferase." [GOC:BHF, GOC:rl] +is_a: GO:0004857 ! enzyme inhibitor activity +is_a: GO:0055106 ! ubiquitin-protein transferase regulator activity +relationship: negatively_regulates GO:0004842 ! ubiquitin-protein transferase activity +relationship: part_of GO:0031397 ! negative regulation of protein ubiquitination + +[Term] +id: GO:0055106 +name: ubiquitin-protein transferase regulator activity +namespace: molecular_function +def: "Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein." [GOC:BHF, GOC:rl] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0004842 ! ubiquitin-protein transferase activity + +[Term] +id: GO:0055107 +name: Golgi to secretory granule transport +namespace: biological_process +def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators] +is_a: GO:0046907 ! intracellular transport +relationship: occurs_in GO:0005737 ! cytoplasm + +[Term] +id: GO:0055108 +name: Golgi to transport vesicle transport +namespace: biological_process +def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid] +is_a: GO:0046907 ! intracellular transport +relationship: occurs_in GO:0005737 ! cytoplasm +relationship: part_of GO:0048193 ! Golgi vesicle transport + +[Term] +id: GO:0055109 +name: invagination involved in gastrulation with mouth forming second +namespace: biological_process +def: "The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0001702 ! gastrulation with mouth forming second + +[Term] +id: GO:0055110 +name: involution involved in gastrulation with mouth forming second +namespace: biological_process +def: "The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation." [ISBN:0878932437] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +relationship: part_of GO:0001702 ! gastrulation with mouth forming second + +[Term] +id: GO:0055111 +name: ingression involved in gastrulation with mouth forming second +namespace: biological_process +def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] +is_a: GO:0042074 ! cell migration involved in gastrulation +intersection_of: GO:0001667 ! ameboidal-type cell migration +intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second +relationship: part_of GO:0001702 ! gastrulation with mouth forming second + +[Term] +id: GO:0055112 +name: delamination involved in gastrulation with mouth forming second +namespace: biological_process +def: "The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation." [ISBN:0878932437] +is_a: GO:0060232 ! delamination +intersection_of: GO:0060232 ! delamination +intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second +relationship: part_of GO:0001702 ! gastrulation with mouth forming second + +[Term] +id: GO:0055113 +name: epiboly involved in gastrulation with mouth forming second +namespace: biological_process +def: "The expansion of one cell sheet over other cells involved in deuterostomic gastrulation." [ISBN:0878932437] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0090504 ! epiboly +intersection_of: GO:0090504 ! epiboly +intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second +relationship: part_of GO:0001702 ! gastrulation with mouth forming second + +[Term] +id: GO:0055114 +name: oxidation-reduction process +namespace: biological_process +def: "A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons." [GOC:dhl, GOC:ecd, GOC:jh2, GOC:jid, GOC:mlg, GOC:rph] +subset: goslim_pir +synonym: "oxidation reduction" EXACT [] +synonym: "oxidoreductase process" EXACT systematic_synonym [] +xref: Wikipedia:Redox +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0055115 +name: entry into diapause +namespace: biological_process +def: "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." [GOC:ds, GOC:jid, GOC:mah] +xref: Wikipedia:Diapause +is_a: GO:0022611 ! dormancy process + +[Term] +id: GO:0055116 +name: entry into reproductive diapause +namespace: biological_process +def: "The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:ds, GOC:jid, GOC:mah] +is_a: GO:0055115 ! entry into diapause + +[Term] +id: GO:0055117 +name: regulation of cardiac muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] +is_a: GO:0006942 ! regulation of striated muscle contraction +is_a: GO:0008016 ! regulation of heart contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060048 ! cardiac muscle contraction +relationship: regulates GO:0060048 ! cardiac muscle contraction + +[Term] +id: GO:0055118 +name: negative regulation of cardiac muscle contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] +is_a: GO:0045822 ! negative regulation of heart contraction +is_a: GO:0045988 ! negative regulation of striated muscle contraction +is_a: GO:0055117 ! regulation of cardiac muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060048 ! cardiac muscle contraction +relationship: negatively_regulates GO:0060048 ! cardiac muscle contraction + +[Term] +id: GO:0055119 +name: relaxation of cardiac muscle +namespace: biological_process +def: "The process in which the extent of cardiac muscle contraction is reduced." [GOC:ecd] +is_a: GO:0090075 ! relaxation of muscle + +[Term] +id: GO:0055120 +name: striated muscle dense body +namespace: cellular_component +def: "A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere." [GOC:kmv, PMID:17492481] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043292 ! contractile fiber + +[Term] +id: GO:0055121 +name: response to high fluence blue light stimulus by blue high-fluence system +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2." [GOC:mtg_far_red] +synonym: "response to high fluence blue light" BROAD [] +synonym: "response to high fluence blue light by bhf system" RELATED [] +is_a: GO:0009637 ! response to blue light +is_a: GO:0009644 ! response to high light intensity + +[Term] +id: GO:0055122 +name: response to very low light intensity stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec." [GOC:mtg_far_red] +is_a: GO:0009642 ! response to light intensity + +[Term] +id: GO:0055123 +name: digestive system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid] +is_a: GO:0048731 ! system development + +[Term] +id: GO:0055124 +name: obsolete premature neural plate formation +namespace: biological_process +def: "OBSOLETE. The formation of the neural plate before the appropriate time." [GOC:jid] +synonym: "premature neural plate formation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0055125 +name: obsolete Nic96 complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p." [GOC:jh, PMID:12791264, PMID:15741174] +synonym: "Nic96 complex" EXACT [] +is_obsolete: true +consider: GO:0044612 +created_by: jid +creation_date: 2009-10-12T08:35:18Z + +[Term] +id: GO:0055126 +name: obsolete Nup82 complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p." [GOC:jh, PMID:12791264, PMID:15741174] +synonym: "Nup82 complex" EXACT [] +is_obsolete: true +consider: GO:0044612 +created_by: jid +creation_date: 2009-10-12T08:35:34Z + +[Term] +id: GO:0055127 +name: vibrational conductance of sound to the inner ear +namespace: biological_process +def: "The transmission of vibrations via ossicles to the inner ear." [GOC:mh] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0007605 ! sensory perception of sound +created_by: jid +creation_date: 2009-10-13T10:59:39Z + +[Term] +id: GO:0055129 +name: L-proline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins." [GOC:ecd] +synonym: "pyrrolidine-2-carboxylic acid biosynthetic process" BROAD [] +is_a: GO:0006561 ! proline biosynthetic process +is_a: GO:0017144 ! drug metabolic process +created_by: jid +creation_date: 2009-10-22T01:59:56Z + +[Term] +id: GO:0055130 +name: D-alanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine." [GOC:ecd] +synonym: "(2R)-2-aminopropanoic acid catabolic process" EXACT [] +is_a: GO:0006524 ! alanine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:0046436 ! D-alanine metabolic process +created_by: jid +creation_date: 2009-10-22T02:02:42Z + +[Term] +id: GO:0055131 +name: C3HC4-type RING finger domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway." [GOC:amm, InterPro:IPR001841, InterPro:IPR018957] +is_a: GO:0019904 ! protein domain specific binding +created_by: jid +creation_date: 2009-10-22T02:20:33Z + +[Term] +id: GO:0060001 +name: minus-end directed microfilament motor activity +namespace: molecular_function +def: "Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers." [GOC:dph, PMID:10519557] +synonym: "minus-end directed actin filament motor activity" RELATED [GOC:dph] +synonym: "minus-end directed actin-filament motor activity" EXACT [GOC:dph] +synonym: "pointed-end directed actin-filament motor activity" EXACT [GOC:dph] +is_a: GO:0000146 ! microfilament motor activity + +[Term] +id: GO:0060002 +name: plus-end directed microfilament motor activity +namespace: molecular_function +def: "Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers." [GOC:dph, PMID:10519557] +synonym: "barbed-end directed actin-filament motor activity" EXACT [GOC:dph] +synonym: "plus-end directed actin filament motor activity" RELATED [GOC:dph] +synonym: "plus-end directed actin-filament motor activity" EXACT [GOC:dph] +is_a: GO:0000146 ! microfilament motor activity + +[Term] +id: GO:0060003 +name: copper ion export +namespace: biological_process +def: "The directed movement of copper ions out of a cell or organelle." [GOC:dph] +synonym: "copper export" EXACT [GOC:dph] +is_a: GO:0035434 ! copper ion transmembrane transport + +[Term] +id: GO:0060004 +name: reflex +namespace: biological_process +def: "An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness." [GOC:dph, ISBN:0877797099] +xref: Wikipedia:Reflex +is_a: GO:0009605 ! response to external stimulus + +[Term] +id: GO:0060005 +name: vestibular reflex +namespace: biological_process +def: "A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [PMID:11784757] +is_a: GO:0060004 ! reflex + +[Term] +id: GO:0060006 +name: angular vestibuloocular reflex +namespace: biological_process +def: "A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [GOC:dph, PMID:11784757] +is_a: GO:0060005 ! vestibular reflex + +[Term] +id: GO:0060007 +name: linear vestibuloocular reflex +namespace: biological_process +def: "A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness." [GOC:dph, PMID:11784757] +is_a: GO:0060005 ! vestibular reflex + +[Term] +id: GO:0060008 +name: Sertoli cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0008584 ! male gonad development + +[Term] +id: GO:0060009 +name: Sertoli cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph] +is_a: GO:0002064 ! epithelial cell development +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0060008 ! Sertoli cell differentiation + +[Term] +id: GO:0060010 +name: Sertoli cell fate commitment +namespace: biological_process +def: "The process in which the cellular identity of Sertoli cells is acquired and determined." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0060008 ! Sertoli cell differentiation + +[Term] +id: GO:0060011 +name: Sertoli cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0050673 ! epithelial cell proliferation +relationship: part_of GO:0008584 ! male gonad development + +[Term] +id: GO:0060012 +name: synaptic transmission, glycinergic +namespace: biological_process +def: "The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos] +synonym: "glycinergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0060013 +name: righting reflex +namespace: biological_process +def: "A reflex process in which an animal immediately tries to turn over after being placed in a supine position." [GOC:dph, PMID:8635460] +synonym: "righting response" EXACT [GOC:dph] +is_a: GO:0060004 ! reflex + +[Term] +id: GO:0060014 +name: granulosa cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals." [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0060015 +name: granulosa cell fate commitment +namespace: biological_process +def: "The cell fate commitment of precursor cells that will become granulosa cells." [GOC:dph] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0060014 ! granulosa cell differentiation + +[Term] +id: GO:0060016 +name: granulosa cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate." [GOC:dph] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0060014 ! granulosa cell differentiation + +[Term] +id: GO:0060017 +name: parathyroid gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone." [GOC:dph, ISBN:0721662544] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0035270 ! endocrine system development + +[Term] +id: GO:0060018 +name: astrocyte fate commitment +namespace: biological_process +def: "The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte." [GOC:dph] +is_a: GO:0021781 ! glial cell fate commitment +relationship: part_of GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0060019 +name: radial glial cell differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph] +is_a: GO:0010001 ! glial cell differentiation + +[Term] +id: GO:0060020 +name: Bergmann glial cell differentiation +namespace: biological_process +def: "The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, PMID:10375501] +is_a: GO:0048708 ! astrocyte differentiation + +[Term] +id: GO:0060021 +name: roof of mouth development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544] +synonym: "palatum development" EXACT [ISBN:0721662544] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0060022 +name: hard palate development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes." [GOC:dph, ISBN:0721662544] +synonym: "palatum durum development" EXACT [ISBN:0721662544] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0062009 ! secondary palate development + +[Term] +id: GO:0060023 +name: soft palate development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate." [GOC:dph, ISBN:0721662544] +synonym: "palatum molle development" EXACT [ISBN:0721662544] +synonym: "velum palatum development" EXACT [ISBN:0721662544] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0062009 ! secondary palate development +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0060024 +name: rhythmic synaptic transmission +namespace: biological_process +def: "Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit." [GOC:dph] +is_a: GO:0050804 ! modulation of chemical synaptic transmission + +[Term] +id: GO:0060025 +name: regulation of synaptic activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell." [GOC:dph, GOC:tb] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +relationship: part_of GO:0050803 ! regulation of synapse structure or activity + +[Term] +id: GO:0060026 +name: convergent extension +namespace: biological_process +def: "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis." [GOC:dgf, GOC:dph, PMID:12062082] +xref: Wikipedia:Convergent_extension +is_a: GO:0002009 ! morphogenesis of an epithelium + +[Term] +id: GO:0060027 +name: convergent extension involved in gastrulation +namespace: biological_process +def: "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:dph, PMID:12062082] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060026 ! convergent extension +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0007369 ! gastrulation + +[Term] +id: GO:0060028 +name: convergent extension involved in axis elongation +namespace: biological_process +def: "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism." [GOC:dph, PMID:12062082] +is_a: GO:0060026 ! convergent extension +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0003401 ! axis elongation +relationship: part_of GO:0003401 ! axis elongation + +[Term] +id: GO:0060029 +name: convergent extension involved in organogenesis +namespace: biological_process +def: "The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ." [GOC:dph, PMID:12062082] +is_a: GO:0060026 ! convergent extension +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0048513 ! animal organ development +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0060030 +name: dorsal convergence +namespace: biological_process +def: "The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement." [GOC:dgf, GOC:dph, PMID:12062082] +is_a: GO:0042074 ! cell migration involved in gastrulation +relationship: part_of GO:0060027 ! convergent extension involved in gastrulation + +[Term] +id: GO:0060031 +name: mediolateral intercalation +namespace: biological_process +def: "The interdigitation of cells along the mediolateral axis during gastrulation." [GOC:dgf, GOC:dph, PMID:12062082] +is_a: GO:0042074 ! cell migration involved in gastrulation +relationship: part_of GO:0060027 ! convergent extension involved in gastrulation + +[Term] +id: GO:0060032 +name: notochord regression +namespace: biological_process +def: "The developmental process in which the stucture of the notochord is destroyed in an embryo." [GOC:dph] +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0048570 ! notochord morphogenesis + +[Term] +id: GO:0060033 +name: anatomical structure regression +namespace: biological_process +def: "The developmental process in which an anatomical stucture is destroyed as a part of its normal progression." [GOC:dph] +synonym: "histolysis" RELATED [GOC:mtg_apoptosis] +synonym: "tissue death" RELATED [GOC:mtg_apoptosis] +is_a: GO:0032502 ! developmental process +relationship: part_of GO:0009653 ! anatomical structure morphogenesis + +[Term] +id: GO:0060034 +name: notochord cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate." [GOC:dph] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030903 ! notochord development + +[Term] +id: GO:0060035 +name: notochord cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060034 ! notochord cell differentiation + +[Term] +id: GO:0060036 +name: notochord cell vacuolation +namespace: biological_process +def: "The assembly and arrangement of a vacuole within a cell of the notochord." [GOC:cb, GOC:dph, PMID:10964477] +is_a: GO:0007033 ! vacuole organization +relationship: part_of GO:0060035 ! notochord cell development + +[Term] +id: GO:0060037 +name: pharyngeal system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph] +is_a: GO:0048731 ! system development +relationship: part_of GO:0043009 ! chordate embryonic development + +[Term] +id: GO:0060038 +name: cardiac muscle cell proliferation +namespace: biological_process +def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571] +synonym: "cardiac myocyte proliferation" EXACT [] +synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473] +synonym: "heart muscle cell proliferation" EXACT [] +is_a: GO:0014855 ! striated muscle cell proliferation +relationship: part_of GO:0055017 ! cardiac muscle tissue growth + +[Term] +id: GO:0060039 +name: pericardium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0060040 +name: retinal bipolar neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina." [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb] +is_a: GO:1905962 ! glutamatergic neuron differentiation +relationship: part_of GO:0003407 ! neural retina development +relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye + +[Term] +id: GO:0060041 +name: retina development in camera-type eye +namespace: biological_process +alt_id: GO:0002073 +def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729] +synonym: "retina development in camera-style eye" EXACT [] +synonym: "retinal development" RELATED [GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043010 ! camera-type eye development + +[Term] +id: GO:0060042 +name: retina morphogenesis in camera-type eye +namespace: biological_process +def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu] +synonym: "retina morphogenesis in camera-style eye" EXACT [] +synonym: "retinogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048593 ! camera-type eye morphogenesis +relationship: part_of GO:0060041 ! retina development in camera-type eye + +[Term] +id: GO:0060043 +name: regulation of cardiac muscle cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] +synonym: "regulation of cardiomyocyte proliferation" RELATED [GOC:dph] +synonym: "regulation of heart muscle cell proliferation" EXACT [] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0055021 ! regulation of cardiac muscle tissue growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060038 ! cardiac muscle cell proliferation +relationship: regulates GO:0060038 ! cardiac muscle cell proliferation + +[Term] +id: GO:0060044 +name: negative regulation of cardiac muscle cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] +synonym: "negative regulation of heart muscle cell proliferation" EXACT [] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth +is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation +relationship: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation + +[Term] +id: GO:0060045 +name: positive regulation of cardiac muscle cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] +synonym: "positive regulation of heart muscle cell proliferation" RELATED [] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth +is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060038 ! cardiac muscle cell proliferation +relationship: positively_regulates GO:0060038 ! cardiac muscle cell proliferation + +[Term] +id: GO:0060046 +name: regulation of acrosome reaction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the acrosome reaction." [GOC:dph] +is_a: GO:0080154 ! regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007340 ! acrosome reaction +relationship: regulates GO:0007340 ! acrosome reaction + +[Term] +id: GO:0060047 +name: heart contraction +namespace: biological_process +def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph] +synonym: "cardiac contraction" RELATED [] +synonym: "heart beating" EXACT [] +synonym: "hemolymph circulation" RELATED [] +is_a: GO:0003015 ! heart process +relationship: part_of GO:0008015 ! blood circulation + +[Term] +id: GO:0060048 +name: cardiac muscle contraction +namespace: biological_process +def: "Muscle contraction of cardiac muscle tissue." [GOC:dph] +synonym: "heart muscle contraction" EXACT [] +is_a: GO:0006941 ! striated muscle contraction +relationship: part_of GO:0060047 ! heart contraction + +[Term] +id: GO:0060049 +name: regulation of protein glycosylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr] +synonym: "regulation of protein amino acid glycosylation" EXACT [GOC:bf] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006486 ! protein glycosylation +relationship: regulates GO:0006486 ! protein glycosylation + +[Term] +id: GO:0060050 +name: positive regulation of protein glycosylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr] +synonym: "positive regulation of protein amino acid glycosylation" EXACT [GOC:bf] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:0060049 ! regulation of protein glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006486 ! protein glycosylation +relationship: positively_regulates GO:0006486 ! protein glycosylation + +[Term] +id: GO:0060051 +name: negative regulation of protein glycosylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph, GOC:pr] +synonym: "negative regulation of protein amino acid glycosylation" EXACT [GOC:bf] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0060049 ! regulation of protein glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006486 ! protein glycosylation +relationship: negatively_regulates GO:0006486 ! protein glycosylation + +[Term] +id: GO:0060052 +name: neurofilament cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins." [GOC:dph] +synonym: "neurofilament cytoskeleton organisation" EXACT [GOC:mah] +synonym: "neurofilament cytoskeleton organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0045104 ! intermediate filament cytoskeleton organization + +[Term] +id: GO:0060053 +name: neurofilament cytoskeleton +namespace: cellular_component +def: "Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons." [GOC:dph] +is_a: GO:0045111 ! intermediate filament cytoskeleton +relationship: has_part GO:0005883 ! neurofilament + +[Term] +id: GO:0060054 +name: positive regulation of epithelial cell proliferation involved in wound healing +namespace: biological_process +def: "Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury." [GOC:dph] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +intersection_of: GO:0050679 ! positive regulation of epithelial cell proliferation +intersection_of: part_of GO:0042060 ! wound healing +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0060055 +name: angiogenesis involved in wound healing +namespace: biological_process +def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury." [GOC:dph, PMID:15039218] +is_a: GO:0001525 ! angiogenesis +intersection_of: GO:0001525 ! angiogenesis +intersection_of: part_of GO:0042060 ! wound healing +relationship: part_of GO:0042060 ! wound healing + +[Term] +id: GO:0060056 +name: mammary gland involution +namespace: biological_process +def: "The tissue remodeling that removes differentiated mammary epithelia during weaning." [GOC:dph, PMID:15282149] +is_a: GO:0048771 ! tissue remodeling +relationship: part_of GO:0060443 ! mammary gland morphogenesis + +[Term] +id: GO:0060057 +name: apoptotic process involved in mammary gland involution +namespace: biological_process +def: "Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death." [GOC:dph, GOC:mtg_apoptosis] +synonym: "apoptosis involved in mammary gland involution" NARROW [] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0060056 ! mammary gland involution +relationship: part_of GO:0060056 ! mammary gland involution + +[Term] +id: GO:0060058 +name: positive regulation of apoptotic process involved in mammary gland involution +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution." [GOC:dph, GOC:mtg_apoptosis, PMID:15282149] +synonym: "positive regulation of apoptosis involved in mammary gland involution" NARROW [] +is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis +is_a: GO:1903521 ! positive regulation of mammary gland involution +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060057 ! apoptotic process involved in mammary gland involution +relationship: positively_regulates GO:0060057 ! apoptotic process involved in mammary gland involution + +[Term] +id: GO:0060059 +name: embryonic retina morphogenesis in camera-type eye +namespace: biological_process +def: "The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage." [GOC:dgh, GOC:dph] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye + +[Term] +id: GO:0060060 +name: post-embryonic retina morphogenesis in camera-type eye +namespace: biological_process +def: "The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage." [GOC:dgh, GOC:dph] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye + +[Term] +id: GO:0060061 +name: Spemann organizer formation +namespace: biological_process +def: "Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan." [GOC:bf, GOC:dph] +synonym: "Spemann's organizer formation" EXACT [] +synonym: "Spemann-Mangold organizer formation" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0031128 ! developmental induction + +[Term] +id: GO:0060062 +name: Spemann organizer formation at the dorsal lip of the blastopore +namespace: biological_process +def: "Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan." [GOC:dph, PMID:9442883] +comment: Occurs in amphibia, cephalochordates, cyclostomes and cartilaginous fish. +synonym: "Spemann's organizer formation at the dorsal lip of the blastopore" EXACT [] +synonym: "Spemann-Mangold organizer formation at the dorsal lip of the blastopore" EXACT [] +is_a: GO:0060061 ! Spemann organizer formation + +[Term] +id: GO:0060063 +name: Spemann organizer formation at the embryonic shield +namespace: biological_process +def: "Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan." [GOC:dph, PMID:9442883] +comment: Occurs in Teleost fish. +synonym: "Spemann's organizer formation at the embryonic shield" EXACT [] +synonym: "Spemann-Mangold organizer formation at the embryonic shield" EXACT [] +is_a: GO:0060061 ! Spemann organizer formation + +[Term] +id: GO:0060064 +name: Spemann organizer formation at the anterior end of the primitive streak +namespace: biological_process +def: "Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan." [GOC:dph, PMID:9442883] +comment: Occurs in reptiles, birds and mammals. +synonym: "Spemann organizer formation in amniotes" RELATED [] +synonym: "Spemann's organizer formation at the anterior end of the primitive streak" EXACT [] +synonym: "Spemann-Mangold organizer formation at the anterior end of the primitive streak" RELATED [] +is_a: GO:0060061 ! Spemann organizer formation + +[Term] +id: GO:0060065 +name: uterus development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] +synonym: "Mullerian tract development" RELATED [] +is_a: GO:0048513 ! animal organ development +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0060066 +name: oviduct development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct] +synonym: "fallopian tube development" NARROW [GOC:bf] +synonym: "Mullerian tract development" RELATED [] +is_a: GO:0035295 ! tube development +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0060067 +name: cervix development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] +synonym: "Mullerian tract development" RELATED [] +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0060068 +name: vagina development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] +is_a: GO:0030540 ! female genitalia development + +[Term] +id: GO:0060069 +name: Wnt signaling pathway, regulating spindle positioning +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle." [GOC:bf, GOC:dph, PMID:11532397] +synonym: "non-canonical Wnt signaling pathway" BROAD [] +synonym: "Wnt receptor signaling pathway, regulating spindle positioning" EXACT [] +synonym: "Wnt receptor signalling pathway, regulating spindle positioning" EXACT [] +synonym: "Wnt-activated signaling pathway, regulating spindle positioning" EXACT [GOC:signaling] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0035567 ! non-canonical Wnt signaling pathway +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0035567 ! non-canonical Wnt signaling pathway +intersection_of: regulates GO:0040001 ! establishment of mitotic spindle localization +relationship: regulates GO:0040001 ! establishment of mitotic spindle localization + +[Term] +id: GO:0060070 +name: canonical Wnt signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:bf, GOC:dph, PMID:11532397, PMID:19619488] +synonym: "canonical Wnt receptor signaling pathway" EXACT [GOC:signaling] +synonym: "canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "frizzled-1 receptor signaling pathway" NARROW [] +synonym: "Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:mtg_signal] +synonym: "Wnt receptor signaling pathway via beta-catenin" EXACT [] +synonym: "Wnt receptor signalling pathway through beta-catenin" EXACT [] +is_a: GO:0016055 ! Wnt signaling pathway + +[Term] +id: GO:0060071 +name: Wnt signaling pathway, planar cell polarity pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity." [GOC:bf, GOC:dph, PMID:11532397] +synonym: "non-canonical Wnt signaling pathway" RELATED [GOC:bf] +synonym: "PCP pathway" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "planar cell polarity pathway" EXACT [GOC:cjm] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway" EXACT [] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway" EXACT [] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway" EXACT [GOC:signaling] +synonym: "Wnt-JNK signaling pathway" RELATED [GOC:bf] +synonym: "Wnt-PCP signaling pathway" RELATED [GOC:rph] +is_a: GO:0035567 ! non-canonical Wnt signaling pathway +is_a: GO:0090175 ! regulation of establishment of planar polarity + +[Term] +id: GO:0060072 +name: large conductance calcium-activated potassium channel activity +namespace: molecular_function +alt_id: GO:0022895 +def: "Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729, PMID:17115074] +synonym: "BK calcium-activated potassium channel activity" EXACT [] +synonym: "BK channel activity" RELATED [] +synonym: "BK KCa channel activity" EXACT [] +synonym: "large conductance KCa channel activity" EXACT [] +is_a: GO:0015269 ! calcium-activated potassium channel activity + +[Term] +id: GO:0060073 +name: micturition +namespace: biological_process +def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph] +synonym: "urination" EXACT [] +synonym: "urine voiding" EXACT [] +xref: Wikipedia:Urination +is_a: GO:0003014 ! renal system process +is_a: GO:0007588 ! excretion + +[Term] +id: GO:0060074 +name: synapse maturation +namespace: biological_process +def: "The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development." [GOC:dph, GOC:ef] +subset: goslim_synapse +synonym: "synaptic maturation" EXACT [] +is_a: GO:0021700 ! developmental maturation +is_a: GO:0050808 ! synapse organization +relationship: part_of GO:0007399 ! nervous system development + +[Term] +id: GO:0060075 +name: regulation of resting membrane potential +namespace: biological_process +def: "Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized." [GOC:dph, GOC:ef, ISBN:0195088433] +synonym: "regulation of resting potential" EXACT [] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0060076 +name: excitatory synapse +namespace: cellular_component +def: "A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef] +xref: Wikipedia:Excitatory_synapse +is_a: GO:0045202 ! synapse +disjoint_from: GO:0060077 ! inhibitory synapse + +[Term] +id: GO:0060077 +name: inhibitory synapse +namespace: cellular_component +def: "A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef] +xref: Wikipedia:Inhibitory_postsynaptic_potential +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0060078 +name: regulation of postsynaptic membrane potential +namespace: biological_process +def: "Any process that modulates the potential difference across a post-synaptic membrane." [GOC:dph, GOC:ef] +subset: goslim_synapse +synonym: "regulation of post-synaptic membrane potential" EXACT [] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0060079 +name: excitatory postsynaptic potential +namespace: biological_process +def: "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:dph, GOC:ef] +synonym: "regulation of EPSP" RELATED [] +synonym: "regulation of excitatory post-synaptic membrane potential" EXACT [] +is_a: GO:0060078 ! regulation of postsynaptic membrane potential +relationship: part_of GO:0099565 ! chemical synaptic transmission, postsynaptic + +[Term] +id: GO:0060080 +name: inhibitory postsynaptic potential +namespace: biological_process +def: "A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential." [GOC:dph, GOC:ef] +synonym: "IPSP" RELATED [] +synonym: "regulation of inhibitory post-synaptic membrane potential" EXACT [] +is_a: GO:0060078 ! regulation of postsynaptic membrane potential +relationship: part_of GO:0099565 ! chemical synaptic transmission, postsynaptic + +[Term] +id: GO:0060081 +name: membrane hyperpolarization +namespace: biological_process +def: "The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential." [GOC:dph] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0060082 +name: eye blink reflex +namespace: biological_process +def: "The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing." [GOC:dph, PMID:2913208] +synonym: "nictitating membrane reflex" EXACT [] +is_a: GO:0060004 ! reflex + +[Term] +id: GO:0060083 +name: smooth muscle contraction involved in micturition +namespace: biological_process +def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347] +synonym: "smooth muscle contraction involved in urination" RELATED [] +synonym: "urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:dph] +is_a: GO:0014832 ! urinary bladder smooth muscle contraction +intersection_of: GO:0006939 ! smooth muscle contraction +intersection_of: part_of GO:0060073 ! micturition +relationship: part_of GO:0060073 ! micturition + +[Term] +id: GO:0060084 +name: synaptic transmission involved in micturition +namespace: biological_process +def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] +synonym: "synaptic transmission involved in urination" RELATED [] +is_a: GO:0007274 ! neuromuscular synaptic transmission +intersection_of: GO:0007268 ! chemical synaptic transmission +intersection_of: part_of GO:0060073 ! micturition +relationship: part_of GO:0060073 ! micturition + +[Term] +id: GO:0060085 +name: smooth muscle relaxation of the bladder outlet +namespace: biological_process +def: "A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] +synonym: "synaptic transmission involved in urination" EXACT [] +is_a: GO:0044557 ! relaxation of smooth muscle +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +relationship: part_of GO:0060073 ! micturition + +[Term] +id: GO:0060086 +name: circadian temperature homeostasis +namespace: biological_process +def: "Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours." [GOC:dph, GOC:tb] +synonym: "circadian regulation of body temperature" RELATED [] +synonym: "circadian thermoregulation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0001659 ! temperature homeostasis +is_a: GO:0007623 ! circadian rhythm + +[Term] +id: GO:0060087 +name: relaxation of vascular smooth muscle +namespace: biological_process +alt_id: GO:1905657 +alt_id: GO:1905658 +alt_id: GO:1905659 +def: "A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:dph, GOC:rph, GOC:TermGenie, PMID:15867178, PMID:19996365, PMID:27389411] +synonym: "negative regulation of relaxation of vascular smooth muscle" RELATED [] +synonym: "positive regulation of relaxation of vascular smooth muscle" RELATED [] +synonym: "regulation of relaxation of vascular smooth muscle" RELATED [] +synonym: "vascular smooth muscle relaxation" EXACT [] +is_a: GO:0044557 ! relaxation of smooth muscle +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +relationship: part_of GO:0042311 ! vasodilation + +[Term] +id: GO:0060088 +name: auditory receptor cell stereocilium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells." [GOC:dph, PMID:10978835] +synonym: "auditory receptor cell stereocilium organisation" EXACT [] +synonym: "auditory receptor cell stereocilium organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0060122 ! inner ear receptor cell stereocilium organization +relationship: part_of GO:0002093 ! auditory receptor cell morphogenesis + +[Term] +id: GO:0060089 +name: molecular transducer activity +namespace: molecular_function +def: "A compound molecular function in which an effector function is controlled by one or more regulatory components." [GOC:dos, GOC:pdt] +subset: gocheck_do_not_manually_annotate +subset: goslim_pir +is_a: GO:0003674 ! molecular_function + +[Term] +id: GO:0060090 +name: molecular adaptor activity +namespace: molecular_function +alt_id: GO:0032947 +def: "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way." [GOC:mtg_MIT_16mar07, GOC:vw] +subset: goslim_drosophila +subset: goslim_pir +synonym: "binding, bridging" EXACT [] +synonym: "protein complex scaffold activity" RELATED [] +synonym: "protein-containing complex scaffold activity" RELATED [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0060091 +name: kinocilium +namespace: cellular_component +def: "A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia." [GOC:cilia, GOC:dph, PMID:15882574] +xref: Wikipedia:Kinocilium +is_a: GO:0043005 ! neuron projection +is_a: GO:0097732 ! 9+2 non-motile cilium +relationship: part_of GO:0032421 ! stereocilium bundle +relationship: part_of GO:0043226 ! organelle + +[Term] +id: GO:0060092 +name: regulation of synaptic transmission, glycinergic +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060012 ! synaptic transmission, glycinergic +relationship: regulates GO:0060012 ! synaptic transmission, glycinergic + +[Term] +id: GO:0060093 +name: negative regulation of synaptic transmission, glycinergic +namespace: biological_process +def: "Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] +synonym: "negative regulation of glycinergic synaptic transmission" EXACT [] +is_a: GO:0050805 ! negative regulation of synaptic transmission +is_a: GO:0060092 ! regulation of synaptic transmission, glycinergic +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060012 ! synaptic transmission, glycinergic +relationship: negatively_regulates GO:0060012 ! synaptic transmission, glycinergic + +[Term] +id: GO:0060094 +name: positive regulation of synaptic transmission, glycinergic +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] +synonym: "positive regulation of glycinergic synaptic transmission" EXACT [] +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:0060092 ! regulation of synaptic transmission, glycinergic +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060012 ! synaptic transmission, glycinergic +relationship: positively_regulates GO:0060012 ! synaptic transmission, glycinergic + +[Term] +id: GO:0060095 +name: zinc potentiation of synaptic transmission, glycinergic +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] +synonym: "zinc potentiation of glycinergic synaptic transmission" EXACT [] +is_a: GO:0060094 ! positive regulation of synaptic transmission, glycinergic + +[Term] +id: GO:0060096 +name: serotonin secretion, neurotransmission +namespace: biological_process +def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph] +synonym: "serotonin release, neurotransmission" RELATED [GOC:tb] +is_a: GO:0001820 ! serotonin secretion +is_a: GO:0007269 ! neurotransmitter secretion + +[Term] +id: GO:0060097 +name: cytoskeletal rearrangement involved in phagocytosis, engulfment +namespace: biological_process +def: "The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] +is_a: GO:0007010 ! cytoskeleton organization +intersection_of: GO:0007010 ! cytoskeleton organization +intersection_of: part_of GO:0006911 ! phagocytosis, engulfment +relationship: part_of GO:0006911 ! phagocytosis, engulfment + +[Term] +id: GO:0060098 +name: membrane reorganization involved in phagocytosis, engulfment +namespace: biological_process +def: "The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] +synonym: "membrane reorganisation involved in phagocytosis, engulfment" EXACT [GOC:mah] +is_a: GO:0007009 ! plasma membrane organization +relationship: part_of GO:0006911 ! phagocytosis, engulfment + +[Term] +id: GO:0060099 +name: regulation of phagocytosis, engulfment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:0050764 ! regulation of phagocytosis +is_a: GO:1905153 ! regulation of membrane invagination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006911 ! phagocytosis, engulfment +relationship: regulates GO:0006911 ! phagocytosis, engulfment + +[Term] +id: GO:0060100 +name: positive regulation of phagocytosis, engulfment +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:0050766 ! positive regulation of phagocytosis +is_a: GO:0060099 ! regulation of phagocytosis, engulfment +is_a: GO:1905155 ! positive regulation of membrane invagination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006911 ! phagocytosis, engulfment +relationship: positively_regulates GO:0006911 ! phagocytosis, engulfment + +[Term] +id: GO:0060101 +name: negative regulation of phagocytosis, engulfment +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:0050765 ! negative regulation of phagocytosis +is_a: GO:0060099 ! regulation of phagocytosis, engulfment +is_a: GO:1905154 ! negative regulation of membrane invagination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006911 ! phagocytosis, engulfment +relationship: negatively_regulates GO:0006911 ! phagocytosis, engulfment + +[Term] +id: GO:0060102 +name: collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0060103 +name: obsolete collagen and cuticulin-based cuticle extracellular matrix part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer." [GOC:dph] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: GO:0060102 + +[Term] +id: GO:0060104 +name: surface coat of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "surface coat of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060105 +name: epicuticle of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060106 +name: cortical layer of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060107 +name: annuli extracellular matrix +namespace: cellular_component +def: "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "annulae" RELATED [] +synonym: "annular rings" RELATED [] +synonym: "annule(s)" RELATED [] +synonym: "annulus" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060106 ! cortical layer of collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060108 +name: annular furrow extracellular matrix +namespace: cellular_component +def: "The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline." [GOC:dph, GOC:kmv, ISSN:15518507] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060106 ! cortical layer of collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060109 +name: medial layer of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "medial layer struts" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060110 +name: basal layer of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "basal layer of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060111 +name: alae of collagen and cuticulin-based cuticle extracellular matrix +namespace: cellular_component +def: "Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively." [GOC:dph, GOC:kmv, ISSN:15518507] +synonym: "alae of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060102 ! collagen and cuticulin-based cuticle extracellular matrix + +[Term] +id: GO:0060112 +name: generation of ovulation cycle rhythm +namespace: biological_process +def: "The process which controls the timing of the type of sexual cycle seen in female mammals." [GOC:dph] +synonym: "generation of estrus cycle rhythm" EXACT [] +synonym: "generation of menstrual cycle rhythm" RELATED [] +synonym: "generation of oestrus cycle rhythm" EXACT [] +is_a: GO:0022602 ! ovulation cycle process + +[Term] +id: GO:0060113 +name: inner ear receptor cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound." [GOC:dph] +synonym: "inner ear hair cell differentiation" EXACT [] +is_a: GO:0042490 ! mechanoreceptor differentiation +relationship: part_of GO:0048839 ! inner ear development + +[Term] +id: GO:0060114 +name: vestibular receptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell." [GOC:dph] +synonym: "vestibular hair cell differentiation" EXACT [] +is_a: GO:0035315 ! hair cell differentiation +is_a: GO:0060113 ! inner ear receptor cell differentiation + +[Term] +id: GO:0060115 +name: vestibular receptor cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become a vestibular receptor cell." [GOC:dph] +synonym: "vestibular hair cell fate commitment" EXACT [] +is_a: GO:0060120 ! inner ear receptor cell fate commitment +relationship: part_of GO:0060114 ! vestibular receptor cell differentiation + +[Term] +id: GO:0060116 +name: vestibular receptor cell morphogenesis +namespace: biological_process +def: "Any process that alters the size or shape of a vestibular receptor cell." [GOC:dph, GOC:tb] +synonym: "vestibular hair cell morphogenesis" EXACT [] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation +relationship: part_of GO:0042472 ! inner ear morphogenesis +relationship: part_of GO:0060118 ! vestibular receptor cell development + +[Term] +id: GO:0060117 +name: auditory receptor cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph] +synonym: "auditory hair cell development" EXACT [] +is_a: GO:0002066 ! columnar/cuboidal epithelial cell development +is_a: GO:0060119 ! inner ear receptor cell development +relationship: part_of GO:0042491 ! inner ear auditory receptor cell differentiation + +[Term] +id: GO:0060118 +name: vestibular receptor cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph] +synonym: "vestibular hair cell development" EXACT [] +is_a: GO:0060119 ! inner ear receptor cell development +relationship: part_of GO:0060114 ! vestibular receptor cell differentiation + +[Term] +id: GO:0060119 +name: inner ear receptor cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph] +synonym: "inner ear hair cell development" EXACT [] +is_a: GO:0048666 ! neuron development +relationship: part_of GO:0060113 ! inner ear receptor cell differentiation + +[Term] +id: GO:0060120 +name: inner ear receptor cell fate commitment +namespace: biological_process +def: "The process in which a cell becomes committed to become an inner ear receptor cell." [GOC:dph] +synonym: "inner ear hair cell fate commitment" EXACT [] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0060113 ! inner ear receptor cell differentiation + +[Term] +id: GO:0060121 +name: vestibular receptor cell stereocilium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells." [GOC:dph] +synonym: "vestibular hair cell stereocilium organization" EXACT [] +synonym: "vestibular receptor cell stereocilium organisation" EXACT [GOC:mah] +synonym: "vestibular receptor cell stereocilium organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0060122 ! inner ear receptor cell stereocilium organization +is_a: GO:0106027 ! neuron projection organization +relationship: part_of GO:0060116 ! vestibular receptor cell morphogenesis + +[Term] +id: GO:0060122 +name: inner ear receptor cell stereocilium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells." [GOC:dph] +synonym: "inner ear hair cell receptor stereocilium organization" EXACT [] +synonym: "inner ear receptor stereocilium organisation" EXACT [GOC:mah] +synonym: "inner ear receptor stereocilium organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0031175 ! neuron projection development +relationship: part_of GO:0060119 ! inner ear receptor cell development + +[Term] +id: GO:0060123 +name: regulation of growth hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph] +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030252 ! growth hormone secretion +relationship: regulates GO:0030252 ! growth hormone secretion + +[Term] +id: GO:0060124 +name: positive regulation of growth hormone secretion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph] +is_a: GO:0060123 ! regulation of growth hormone secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030252 ! growth hormone secretion +relationship: positively_regulates GO:0030252 ! growth hormone secretion + +[Term] +id: GO:0060125 +name: negative regulation of growth hormone secretion +namespace: biological_process +def: "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell." [GOC:dph] +is_a: GO:0060123 ! regulation of growth hormone secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030252 ! growth hormone secretion +relationship: negatively_regulates GO:0030252 ! growth hormone secretion + +[Term] +id: GO:0060126 +name: somatotropin secreting cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." [GOC:dph] +synonym: "growth hormone secreting cell differentiation" EXACT [] +synonym: "somatotrope differentiation" RELATED [] +synonym: "somatotroph differentiation" RELATED [] +synonym: "somatotrophin secreting cell differentiation" EXACT [] +synonym: "somatotropic cell differentiation" RELATED [] +synonym: "somatrophic cell differentiation" RELATED [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021984 ! adenohypophysis development + +[Term] +id: GO:0060127 +name: prolactin secreting cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." [GOC:dph] +synonym: "epsilon-acidophil differentiation" EXACT [] +synonym: "lactotrope differentiation" EXACT [] +synonym: "lactotroph differentiation" EXACT [] +synonym: "lactotropic cell differentiation" EXACT [] +synonym: "mammotrope differentiation" EXACT [] +synonym: "mammotroph differentiation" EXACT [] +synonym: "mammotrophic cell differentiation" EXACT [] +synonym: "mammotropic cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021984 ! adenohypophysis development + +[Term] +id: GO:0060128 +name: corticotropin hormone secreting cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." [GOC:dph] +synonym: "adrenocorticotrophic hormone secreting cell differentiation" EXACT [] +synonym: "adrenocorticotropic hormone secreting cell differentiation" EXACT [GOC:dph] +synonym: "corticotrope differentiation" EXACT [] +synonym: "corticotroph differentiation" EXACT [] +synonym: "corticotrophin hormone secreting cell differentiation" RELATED [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0021984 ! adenohypophysis development + +[Term] +id: GO:0060129 +name: thyroid-stimulating hormone-secreting cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin." [GOC:dph] +synonym: "beta-basophil differentiation" EXACT [] +synonym: "thyroid stimulating hormone secreting cell differentiation" EXACT [] +synonym: "thyrotrope differentiation" EXACT [] +synonym: "thyrotroph differentiation" EXACT [] +synonym: "TSH-secreting cell differentiation" EXACT [] +is_a: GO:0002067 ! glandular epithelial cell differentiation +is_a: GO:0061101 ! neuroendocrine cell differentiation +relationship: part_of GO:0021984 ! adenohypophysis development + +[Term] +id: GO:0060130 +name: thyroid-stimulating hormone-secreting cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin." [GOC:dph] +synonym: "beta-basophil development" EXACT [] +synonym: "thyroid stimulating hormone secreting cell development" EXACT [] +synonym: "thyrotrope development" EXACT [] +synonym: "thyrotroph development" EXACT [] +synonym: "TSH-secreting cell development" EXACT [] +is_a: GO:0002068 ! glandular epithelial cell development +relationship: part_of GO:0060129 ! thyroid-stimulating hormone-secreting cell differentiation + +[Term] +id: GO:0060131 +name: corticotropin hormone secreting cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin." [GOC:dph] +synonym: "adrenocorticotrophic hormone secreting cell development" EXACT [] +synonym: "adrenocorticotropic hormone secreting cell development" EXACT [GOC:dph] +synonym: "corticotrope development" EXACT [] +synonym: "corticotroph development" RELATED [] +synonym: "corticotrophin hormone secreting cell development" RELATED [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060128 ! corticotropin hormone secreting cell differentiation + +[Term] +id: GO:0060132 +name: prolactin secreting cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin." [GOC:dph] +synonym: "epsilon-acidophil development" EXACT [] +synonym: "lactotrope development" EXACT [] +synonym: "lactotroph development" EXACT [] +synonym: "lactotropic cell development" EXACT [] +synonym: "mammotrope development" EXACT [] +synonym: "mammotroph development" EXACT [] +synonym: "mammotrophic cell development" EXACT [] +synonym: "mammotropic cell development" EXACT [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060127 ! prolactin secreting cell differentiation + +[Term] +id: GO:0060133 +name: somatotropin secreting cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin." [GOC:dph] +synonym: "growth hormone secreting cell development" EXACT [] +synonym: "somatotrope development" RELATED [] +synonym: "somatotroph development" RELATED [] +synonym: "somatotrophin secreting cell development" EXACT [] +synonym: "somatotropic cell development" EXACT [] +synonym: "somatrophic cell development" RELATED [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060126 ! somatotropin secreting cell differentiation + +[Term] +id: GO:0060134 +name: prepulse inhibition +namespace: biological_process +def: "The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse." [GOC:dph, PMID:10341260] +synonym: "PPI" RELATED [] +synonym: "pre-pulse inhibition" EXACT [] +xref: Wikipedia:Prepulse_inhibition +is_a: GO:0032102 ! negative regulation of response to external stimulus +relationship: part_of GO:0001964 ! startle response + +[Term] +id: GO:0060135 +name: maternal process involved in female pregnancy +namespace: biological_process +def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007565 ! female pregnancy + +[Term] +id: GO:0060136 +name: embryonic process involved in female pregnancy +namespace: biological_process +def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph] +is_a: GO:0048609 ! multicellular organismal reproductive process +intersection_of: GO:0022414 ! reproductive process +intersection_of: part_of GO:0007565 ! female pregnancy +intersection_of: part_of GO:0009790 ! embryo development +relationship: part_of GO:0007565 ! female pregnancy +relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching + +[Term] +id: GO:0060137 +name: maternal process involved in parturition +namespace: biological_process +def: "A reproductive process occurring in the mother that results in birth." [GOC:dph] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007567 ! parturition + +[Term] +id: GO:0060138 +name: fetal process involved in parturition +namespace: biological_process +def: "A reproductive process occurring in the embryo that results in birth." [GOC:dph] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007567 ! parturition +relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching + +[Term] +id: GO:0060139 +name: positive regulation of apoptotic process by virus +namespace: biological_process +def: "Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:dph, GOC:mtg_apoptosis] +synonym: "positive regulation of apoptosis by virus" NARROW [] +is_a: GO:0039526 ! modulation by virus of host apoptotic process +is_a: GO:0052151 ! positive regulation by symbiont of host apoptotic process +intersection_of: GO:0019048 ! modulation by virus of host process +intersection_of: positively_regulates GO:0006915 ! apoptotic process + +[Term] +id: GO:0060140 +name: modulation by virus of syncytium formation via plasma membrane fusion +namespace: biological_process +def: "The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] +is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion +relationship: part_of GO:0006948 ! induction by virus of host cell-cell fusion + +[Term] +id: GO:0060141 +name: positive regulation of syncytium formation by virus +namespace: biological_process +def: "The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] +synonym: "syncytium formation induced by viral infection" EXACT [UniProtKB-KW:KW-1180] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0060140 ! modulation by virus of syncytium formation via plasma membrane fusion +is_a: GO:0060143 ! positive regulation of syncytium formation by plasma membrane fusion + +[Term] +id: GO:0060142 +name: regulation of syncytium formation by plasma membrane fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000768 ! syncytium formation by plasma membrane fusion +relationship: regulates GO:0000768 ! syncytium formation by plasma membrane fusion + +[Term] +id: GO:0060143 +name: positive regulation of syncytium formation by plasma membrane fusion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion +relationship: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion + +[Term] +id: GO:0060144 +name: host cellular process involved in virus induced gene silencing +namespace: biological_process +def: "A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes." [GOC:dph] +is_a: GO:0051702 ! interaction with symbiont +relationship: part_of GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0060145 +name: viral gene silencing in virus induced gene silencing +namespace: biological_process +def: "The posttranscriptional gene silencing of viral genes after viral infection." [GOC:dph] +is_a: GO:0016441 ! posttranscriptional gene silencing +relationship: part_of GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0060146 +name: host gene silencing in virus induced gene silencing +namespace: biological_process +def: "The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection." [GOC:dph] +is_a: GO:0016441 ! posttranscriptional gene silencing +relationship: part_of GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0060147 +name: regulation of posttranscriptional gene silencing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] +is_a: GO:0010468 ! regulation of gene expression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016441 ! posttranscriptional gene silencing +relationship: regulates GO:0016441 ! posttranscriptional gene silencing + +[Term] +id: GO:0060148 +name: positive regulation of posttranscriptional gene silencing +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0060147 ! regulation of posttranscriptional gene silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016441 ! posttranscriptional gene silencing +relationship: positively_regulates GO:0016441 ! posttranscriptional gene silencing + +[Term] +id: GO:0060149 +name: negative regulation of posttranscriptional gene silencing +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0060147 ! regulation of posttranscriptional gene silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016441 ! posttranscriptional gene silencing +relationship: negatively_regulates GO:0016441 ! posttranscriptional gene silencing + +[Term] +id: GO:0060150 +name: viral triggering of virus induced gene silencing +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the inactivation of gene expression of both viral genes and host homologues to those genes by a posttranscriptional mechanism in a virally infected cell." [GOC:dph] +is_a: GO:0060148 ! positive regulation of posttranscriptional gene silencing +relationship: part_of GO:0009616 ! virus induced gene silencing + +[Term] +id: GO:0060151 +name: peroxisome localization +namespace: biological_process +def: "Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:dph, PMID:16449325] +synonym: "peroxisome localisation" EXACT [GOC:mah] +is_a: GO:0051640 ! organelle localization + +[Term] +id: GO:0060152 +name: microtubule-based peroxisome localization +namespace: biological_process +def: "The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:dph, PMID:16449325] +synonym: "microtubule-based peroxisome localisation" EXACT [GOC:mah] +is_a: GO:0007017 ! microtubule-based process +is_a: GO:0060151 ! peroxisome localization + +[Term] +id: GO:0060153 +name: modulation by virus of host cell cycle +namespace: biological_process +def: "Any viral process that modulates the rate or extent of progression through the cell cycle." [GOC:dph, UniProtKB-KW:KW-1121, VZ:1636] +synonym: "modulation of host cell cycle by virus" EXACT [UniProtKB-KW:KW-1121] +synonym: "regulation by virus of host cell cycle" EXACT [] +synonym: "regulation of host cell cycle by virus" EXACT [] +synonym: "viral process regulating host cell cycle" EXACT [] +xref: VZ:1636 "Modulation of host cell cycle by virus" +is_a: GO:0019055 ! modification by virus of host cell cycle regulation + +[Term] +id: GO:0060154 +name: obsolete cellular process regulating host cell cycle in response to virus +namespace: biological_process +def: "OBSOLETE. Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus." [GOC:dph] +comment: The reason for obsoletion is that based on the definition, it is not clear that this process exists. +is_obsolete: true + +[Term] +id: GO:0060155 +name: platelet dense granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins." [GOC:dph, PMID:11487378] +synonym: "bull's eye body organization and biogenesis" RELATED [] +synonym: "platelet dense body organization and biogenesis" RELATED [] +synonym: "platelet dense granule organisation" EXACT [GOC:mah] +synonym: "platelet dense granule organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0033363 ! secretory granule organization + +[Term] +id: GO:0060156 +name: milk ejection reflex +namespace: biological_process +def: "A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness." [GOC:cjm, GOC:dph, GOC:mr, GOC:st] +synonym: "milk ejection" EXACT [] +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0032941 ! secretion by tissue +is_a: GO:0060004 ! reflex +relationship: part_of GO:0007595 ! lactation + +[Term] +id: GO:0060157 +name: urinary bladder development +namespace: biological_process +def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0072001 ! renal system development +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0060158 +name: phospholipase C-activating dopamine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:dph, GOC:signaling, GOC:tb, PMID:12675914] +synonym: "activation of phospholipase C activity by dopamine receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of phospholipase C activity by dopamine receptor signalling pathway" RELATED [GOC:mah] +synonym: "dopamine receptor, phospholipase C activating pathway" RELATED [GOC:dph, GOC:tb] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0060159 +name: regulation of dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "regulation of dopamine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:2001038 ! regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007212 ! dopamine receptor signaling pathway +relationship: regulates GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0060160 +name: negative regulation of dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "negative regulation of dopamine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0060159 ! regulation of dopamine receptor signaling pathway +is_a: GO:2001039 ! negative regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007212 ! dopamine receptor signaling pathway +relationship: negatively_regulates GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0060161 +name: positive regulation of dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "positive regulation of dopamine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0060159 ! regulation of dopamine receptor signaling pathway +is_a: GO:2001040 ! positive regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007212 ! dopamine receptor signaling pathway +relationship: positively_regulates GO:0007212 ! dopamine receptor signaling pathway + +[Term] +id: GO:0060162 +name: negative regulation of phospholipase C-activating dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway." [GOC:dph, GOC:tb, PMID:15016423] +synonym: "negative regulation of dopamine receptor, phospholipase C activating pathway" EXACT [GOC:dph, GOC:tb] +synonym: "negative regulation of phospholipase C-activating dopamine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0060160 ! negative regulation of dopamine receptor signaling pathway +is_a: GO:1900737 ! negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060158 ! phospholipase C-activating dopamine receptor signaling pathway +relationship: negatively_regulates GO:0060158 ! phospholipase C-activating dopamine receptor signaling pathway + +[Term] +id: GO:0060163 +name: subpallium neuron fate commitment +namespace: biological_process +def: "The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon." [GOC:dph] +synonym: "subpallium neuronal precursor fate commitment" RELATED [] +is_a: GO:0048663 ! neuron fate commitment +relationship: part_of GO:0021544 ! subpallium development + +[Term] +id: GO:0060164 +name: regulation of timing of neuron differentiation +namespace: biological_process +def: "The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron." [GOC:dph] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:0048505 ! regulation of timing of cell differentiation + +[Term] +id: GO:0060165 +name: regulation of timing of subpallium neuron differentiation +namespace: biological_process +def: "The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon." [GOC:dph] +is_a: GO:0060164 ! regulation of timing of neuron differentiation +relationship: part_of GO:0021544 ! subpallium development + +[Term] +id: GO:0060166 +name: olfactory pit development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx." [GOC:dph, ISBN:0124020607] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043584 ! nose development + +[Term] +id: GO:0060167 +name: regulation of adenosine receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "regulation of adenosine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway +relationship: regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway + +[Term] +id: GO:0060168 +name: positive regulation of adenosine receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "positive regulation of adenosine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0060167 ! regulation of adenosine receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway +relationship: positively_regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway + +[Term] +id: GO:0060169 +name: negative regulation of adenosine receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "negative regulation of adenosine receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0060167 ! regulation of adenosine receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway +relationship: negatively_regulates GO:0001973 ! G protein-coupled adenosine receptor signaling pathway + +[Term] +id: GO:0060170 +name: ciliary membrane +namespace: cellular_component +alt_id: GO:0020017 +def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "cilial membrane" EXACT [] +synonym: "cilium membrane" EXACT [] +synonym: "flagellar membrane" NARROW [] +synonym: "flagellum membrane" NARROW [] +is_a: GO:0031253 ! cell projection membrane +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0005929 ! cilium + +[Term] +id: GO:0060171 +name: stereocilium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a stereocilium." [GOC:dph, GOC:rph] +is_a: GO:0032589 ! neuron projection membrane +relationship: part_of GO:0005622 ! intracellular +relationship: part_of GO:0032420 ! stereocilium + +[Term] +id: GO:0060172 +name: astral microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GOC:dph] +is_a: GO:0007019 ! microtubule depolymerization +is_a: GO:0030953 ! astral microtubule organization + +[Term] +id: GO:0060173 +name: limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378] +synonym: "limb bud development" NARROW [GOC:dph] +synonym: "paired limb/fin development" EXACT [] +xref: Wikipedia:Limb_development +is_a: GO:0048736 ! appendage development + +[Term] +id: GO:0060174 +name: limb bud formation +namespace: biological_process +def: "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable." [GOC:dgh, GOC:dph] +synonym: "limb formation" EXACT [] +synonym: "limbbud formation" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035108 ! limb morphogenesis + +[Term] +id: GO:0060175 +name: brain-derived neurotrophic factor-activated receptor activity +namespace: molecular_function +def: "Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity." [GOC:bf, GOC:dph] +comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand BDNF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. +synonym: "BDNF receptor activity" RELATED [GOC:dph] +synonym: "BDNF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] +synonym: "brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] +is_a: GO:0004714 ! transmembrane receptor protein tyrosine kinase activity +is_a: GO:0005030 ! neurotrophin receptor activity +relationship: has_part GO:0048403 ! brain-derived neurotrophic factor binding +relationship: part_of GO:0031547 ! brain-derived neurotrophic factor receptor signaling pathway + +[Term] +id: GO:0060176 +name: regulation of aggregation involved in sorocarp development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:dph, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0031156 ! regulation of sorocarp development +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031152 ! aggregation involved in sorocarp development +relationship: regulates GO:0031152 ! aggregation involved in sorocarp development + +[Term] +id: GO:0060177 +name: regulation of angiotensin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin." [GOC:dph, GOC:tb] +synonym: "regulation of angiotensin metabolism" EXACT [] +is_a: GO:0051246 ! regulation of protein metabolic process + +[Term] +id: GO:0060178 +name: regulation of exocyst localization +namespace: biological_process +def: "Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse." [GOC:dph, GOC:tb] +synonym: "regulation of exocyst localisation" EXACT [GOC:mah] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051601 ! exocyst localization +relationship: regulates GO:0051601 ! exocyst localization + +[Term] +id: GO:0060179 +name: male mating behavior +namespace: biological_process +def: "The specific behavior of a male organism that is associated with reproduction." [GOC:dph, GOC:pr, GOC:tb] +is_a: GO:0007617 ! mating behavior + +[Term] +id: GO:0060180 +name: female mating behavior +namespace: biological_process +def: "The specific behavior of a female organism that is associated with reproduction." [GOC:dph, GOC:pr, GOC:tb] +is_a: GO:0007617 ! mating behavior + +[Term] +id: GO:0060182 +name: apelin receptor activity +namespace: molecular_function +def: "Combining with the peptide apelin to initiate a change in cell activity." [GOC:dph] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +relationship: part_of GO:0060183 ! apelin receptor signaling pathway + +[Term] +id: GO:0060183 +name: apelin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands." [GOC:dph] +synonym: "apelin receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0060184 +name: cell cycle switching +namespace: biological_process +def: "The process in which a cell switches cell cycle mode." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0060185 +name: outer ear unfolding +namespace: biological_process +def: "The opening and spreading out of the outer ear." [GOC:dph] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0042473 ! outer ear morphogenesis + +[Term] +id: GO:0060186 +name: outer ear emergence +namespace: biological_process +def: "The growth of the outer ear." [GOC:dph] +synonym: "ear elevation" RELATED [GOC:dph] +synonym: "ear extroversion" RELATED [GOC:dph] +synonym: "outer ear growth" RELATED [GOC:dph] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0042473 ! outer ear morphogenesis + +[Term] +id: GO:0060187 +name: cell pole +namespace: cellular_component +def: "Either of two different areas at opposite ends of an axis of a cell." [GOC:dph] +comment: Note that this term differs from 'cell tip ; GO:0051286' in that it is applicable to a broad range of cell shapes including spherical and cuboidal. +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0060188 +name: regulation of protein desumoylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016926 ! protein desumoylation +relationship: regulates GO:0016926 ! protein desumoylation + +[Term] +id: GO:0060189 +name: positive regulation of protein desumoylation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:0060188 ! regulation of protein desumoylation +is_a: GO:1903322 ! positive regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016926 ! protein desumoylation +relationship: positively_regulates GO:0016926 ! protein desumoylation + +[Term] +id: GO:0060190 +name: negative regulation of protein desumoylation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:0060188 ! regulation of protein desumoylation +is_a: GO:1903321 ! negative regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016926 ! protein desumoylation +relationship: negatively_regulates GO:0016926 ! protein desumoylation + +[Term] +id: GO:0060191 +name: regulation of lipase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:dph, GOC:tb] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016298 ! lipase activity +relationship: regulates GO:0016298 ! lipase activity + +[Term] +id: GO:0060192 +name: negative regulation of lipase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:dph, GOC:tb] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0060191 ! regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016298 ! lipase activity +relationship: negatively_regulates GO:0016298 ! lipase activity + +[Term] +id: GO:0060193 +name: positive regulation of lipase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0060191 ! regulation of lipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016298 ! lipase activity +relationship: positively_regulates GO:0016298 ! lipase activity + +[Term] +id: GO:0060194 +name: regulation of antisense RNA transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:jp, GOC:tb, PMID:18075583] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009300 ! antisense RNA transcription +relationship: regulates GO:0009300 ! antisense RNA transcription + +[Term] +id: GO:0060195 +name: negative regulation of antisense RNA transcription +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:0060194 ! regulation of antisense RNA transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009300 ! antisense RNA transcription +relationship: negatively_regulates GO:0009300 ! antisense RNA transcription + +[Term] +id: GO:0060196 +name: positive regulation of antisense RNA transcription +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:0060194 ! regulation of antisense RNA transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009300 ! antisense RNA transcription +relationship: positively_regulates GO:0009300 ! antisense RNA transcription + +[Term] +id: GO:0060197 +name: cloacal septation +namespace: biological_process +def: "The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development." [GOC:dph, GOC:st] +synonym: "cloaca septation" EXACT [GOC:cjm] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0035844 ! cloaca development + +[Term] +id: GO:0060198 +name: clathrin-sculpted vesicle +namespace: cellular_component +def: "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release." [GOC:dph] +synonym: "clathrin sculpted vesicle" EXACT [GOC:sl] +is_a: GO:0030136 ! clathrin-coated vesicle + +[Term] +id: GO:0060199 +name: clathrin-sculpted glutamate transport vesicle +namespace: cellular_component +def: "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate." [GOC:dph] +synonym: "clathrin sculpted glutamate constitutive secretory pathway transport vesicle" EXACT [] +synonym: "clathrin sculpted glutamate transport vesicle" EXACT [GOC:sl] +is_a: GO:0030133 ! transport vesicle +is_a: GO:0060198 ! clathrin-sculpted vesicle + +[Term] +id: GO:0060200 +name: clathrin-sculpted acetylcholine transport vesicle +namespace: cellular_component +def: "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine." [GOC:dph] +synonym: "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle" EXACT [] +synonym: "clathrin sculpted acetylcholine transport vesicle" EXACT [GOC:sl] +is_a: GO:0030133 ! transport vesicle +is_a: GO:0060198 ! clathrin-sculpted vesicle + +[Term] +id: GO:0060201 +name: clathrin-sculpted acetylcholine transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle." [GOC:dph] +synonym: "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "clathrin sculpted acetylcholine transport vesicle membrane" EXACT [GOC:sl] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030665 ! clathrin-coated vesicle membrane +relationship: part_of GO:0060200 ! clathrin-sculpted acetylcholine transport vesicle + +[Term] +id: GO:0060202 +name: clathrin-sculpted acetylcholine transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle." [GOC:dph] +synonym: "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen" EXACT [] +synonym: "clathrin sculpted acetylcholine transport vesicle lumen" EXACT [GOC:sl] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0060200 ! clathrin-sculpted acetylcholine transport vesicle + +[Term] +id: GO:0060203 +name: clathrin-sculpted glutamate transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle." [GOC:dph] +synonym: "clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "clathrin sculpted glutamate transport vesicle membrane" EXACT [GOC:sl] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030665 ! clathrin-coated vesicle membrane +relationship: part_of GO:0060199 ! clathrin-sculpted glutamate transport vesicle + +[Term] +id: GO:0060204 +name: clathrin-sculpted glutamate transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle." [GOC:dph] +synonym: "clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen" EXACT [] +synonym: "clathrin sculpted glutamate transport vesicle lumen" EXACT [GOC:sl] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0060199 ! clathrin-sculpted glutamate transport vesicle + +[Term] +id: GO:0060205 +name: cytoplasmic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by a cytoplasmic vesicle." [GOC:dph, GOC:vesicles] +synonym: "cytoplasmic membrane-bounded vesicle lumen" RELATED [] +synonym: "cytoplasmic membrane-enclosed vesicle lumen" RELATED [] +is_a: GO:0031983 ! vesicle lumen +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0060206 +name: estrous cycle phase +namespace: biological_process +def: "The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur." [GOC:dph] +subset: gocheck_do_not_annotate +is_a: GO:0044848 ! biological phase + +[Term] +id: GO:0060207 +name: diestrus +namespace: biological_process +def: "The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum." [GOC:dph, ISBN:0721662544] +subset: gocheck_do_not_annotate +is_a: GO:0060206 ! estrous cycle phase + +[Term] +id: GO:0060208 +name: proestrus +namespace: biological_process +def: "The estrous cycle phase in which there is heightened follicular activity." [GOC:dph, ISBN:0721662544] +subset: gocheck_do_not_annotate +is_a: GO:0060206 ! estrous cycle phase + +[Term] +id: GO:0060209 +name: estrus +namespace: biological_process +def: "The estrous cycle phase in which a female is sexually receptive." [GOC:dph, ISBN:0721662544] +subset: gocheck_do_not_annotate +synonym: "oestrus" EXACT [] +is_a: GO:0060206 ! estrous cycle phase + +[Term] +id: GO:0060210 +name: metestrus +namespace: biological_process +def: "The estrous cycle phase in which there is subsiding follicular function." [GOC:dph, ISBN:0721662544] +subset: gocheck_do_not_annotate +is_a: GO:0060206 ! estrous cycle phase + +[Term] +id: GO:0060211 +name: regulation of nuclear-transcribed mRNA poly(A) tail shortening +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] +synonym: "regulation of 3' to 5' mRNA deadenylation" RELATED [] +synonym: "regulation of mRNA deadenylation" RELATED [] +synonym: "regulation of nuclear mRNA poly(A) tail shortening" RELATED [] +is_a: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening +relationship: regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening + +[Term] +id: GO:0060212 +name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] +synonym: "negative regulation of 3' to 5' mRNA deadenylation" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of mRNA deadenylation" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of nuclear mRNA poly(A) tail shortening" RELATED [] +is_a: GO:0060211 ! regulation of nuclear-transcribed mRNA poly(A) tail shortening +is_a: GO:1900152 ! negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening +relationship: negatively_regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening + +[Term] +id: GO:0060213 +name: positive regulation of nuclear-transcribed mRNA poly(A) tail shortening +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] +synonym: "positive regulation of 3' to 5' mRNA deadenylation" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of mRNA deadenylation" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of nuclear mRNA poly(A) tail shortening" RELATED [] +is_a: GO:0060211 ! regulation of nuclear-transcribed mRNA poly(A) tail shortening +is_a: GO:1900153 ! positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening +relationship: positively_regulates GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening + +[Term] +id: GO:0060214 +name: endocardium formation +namespace: biological_process +def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0003160 ! endocardium morphogenesis + +[Term] +id: GO:0060215 +name: primitive hemopoiesis +namespace: biological_process +def: "A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells." [GOC:bf, GOC:dph, PMID:15378083, PMID:15617691] +synonym: "primitive haematopoiesis" EXACT [] +synonym: "primitive haemopoiesis" EXACT [] +synonym: "primitive hematopoiesis" RELATED [] +is_a: GO:0035162 ! embryonic hemopoiesis + +[Term] +id: GO:0060216 +name: definitive hemopoiesis +namespace: biological_process +def: "A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood." [GOC:bf, GOC:dph, PMID:15378083, PMID:15617691] +synonym: "definitive haematopoiesis" RELATED [] +synonym: "definitive haemopoiesis" EXACT [] +synonym: "definitive hematopoiesis" EXACT [] +is_a: GO:0030097 ! hemopoiesis + +[Term] +id: GO:0060217 +name: hemangioblast cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages." [GOC:bf, GOC:dph, PMID:15378083, PMID:9670018] +is_a: GO:0048333 ! mesodermal cell differentiation +relationship: part_of GO:0060215 ! primitive hemopoiesis + +[Term] +id: GO:0060218 +name: hematopoietic stem cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083] +synonym: "haematopoietic stem cell differentiation" EXACT [] +synonym: "haemopoietic stem cell differentiation" EXACT [] +synonym: "hemopoietic stem cell differentiation" EXACT [] +is_a: GO:0002244 ! hematopoietic progenitor cell differentiation +is_a: GO:0048863 ! stem cell differentiation + +[Term] +id: GO:0060219 +name: camera-type eye photoreceptor cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0001754 ! eye photoreceptor cell differentiation +relationship: part_of GO:0003407 ! neural retina development +relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye + +[Term] +id: GO:0060220 +name: camera-type eye photoreceptor cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye." [GOC:dph] +is_a: GO:0042706 ! eye photoreceptor cell fate commitment +relationship: part_of GO:0060219 ! camera-type eye photoreceptor cell differentiation + +[Term] +id: GO:0060221 +name: retinal rod cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph] +is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation + +[Term] +id: GO:0060222 +name: regulation of retinal cone cell fate commitment +namespace: biological_process +def: "Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +is_a: GO:0061074 ! regulation of neural retina development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046551 ! retinal cone cell fate commitment +relationship: regulates GO:0046551 ! retinal cone cell fate commitment + +[Term] +id: GO:0060223 +name: retinal rod cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph] +is_a: GO:0060220 ! camera-type eye photoreceptor cell fate commitment +relationship: part_of GO:0060221 ! retinal rod cell differentiation + +[Term] +id: GO:0060224 +name: regulation of retinal rod cell fate commitment +namespace: biological_process +def: "Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +is_a: GO:0061074 ! regulation of neural retina development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060223 ! retinal rod cell fate commitment +relationship: regulates GO:0060223 ! retinal rod cell fate commitment + +[Term] +id: GO:0060225 +name: positive regulation of retinal rod cell fate commitment +namespace: biological_process +def: "Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation +is_a: GO:0060224 ! regulation of retinal rod cell fate commitment +is_a: GO:0061075 ! positive regulation of neural retina development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060223 ! retinal rod cell fate commitment +relationship: positively_regulates GO:0060223 ! retinal rod cell fate commitment + +[Term] +id: GO:0060226 +name: negative regulation of retinal cone cell fate commitment +namespace: biological_process +def: "Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation +is_a: GO:0060222 ! regulation of retinal cone cell fate commitment +is_a: GO:0061076 ! negative regulation of neural retina development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046551 ! retinal cone cell fate commitment +relationship: negatively_regulates GO:0046551 ! retinal cone cell fate commitment + +[Term] +id: GO:0060227 +name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate." [GOC:dph] +synonym: "Notch signalling pathway involved in camera-type eye photoreceptor fate commitment" EXACT [GOC:mah] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0060220 ! camera-type eye photoreceptor cell fate commitment +relationship: part_of GO:0060220 ! camera-type eye photoreceptor cell fate commitment + +[Term] +id: GO:0060228 +name: phosphatidylcholine-sterol O-acyltransferase activator activity +namespace: molecular_function +def: "Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines." [GOC:BHF, GOC:dph, GOC:tb, PMID:4335615] +synonym: "LCAT activator activity" NARROW [GOC:tb] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0004607 ! phosphatidylcholine-sterol O-acyltransferase activity + +[Term] +id: GO:0060229 +name: lipase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0016298 ! lipase activity + +[Term] +id: GO:0060230 +name: lipoprotein lipase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein." [GOC:BHF, GOC:dph, GOC:tb, PMID:10727238] +is_a: GO:0060229 ! lipase activator activity +relationship: positively_regulates GO:0004465 ! lipoprotein lipase activity + +[Term] +id: GO:0060231 +name: mesenchymal to epithelial transition +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] +synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation + +[Term] +id: GO:0060232 +name: delamination +namespace: biological_process +def: "The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet." [GOC:dph, PMID:16962574, PMID:18343170] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion + +[Term] +id: GO:0060233 +name: oenocyte delamination +namespace: biological_process +def: "The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet." [GOC:dph] +is_a: GO:0060232 ! delamination + +[Term] +id: GO:0060234 +name: neuroblast delamination +namespace: biological_process +def: "The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet." [GOC:dph] +is_a: GO:0060232 ! delamination + +[Term] +id: GO:0060235 +name: lens induction in camera-type eye +namespace: biological_process +def: "Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens." [GOC:dph, ISBN:0878932437] +is_a: GO:0031128 ! developmental induction +relationship: part_of GO:0002089 ! lens morphogenesis in camera-type eye + +[Term] +id: GO:0060236 +name: regulation of mitotic spindle organization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of mitotic spindle organisation" EXACT [GOC:mah] +synonym: "regulation of mitotic spindle organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0090224 ! regulation of spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007052 ! mitotic spindle organization +relationship: regulates GO:0007052 ! mitotic spindle organization + +[Term] +id: GO:0060237 +name: regulation of fungal-type cell wall organization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GOC:dph, GOC:tb] +synonym: "regulation of fungal-type cell wall organisation" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall organization and biogenesis" RELATED [] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031505 ! fungal-type cell wall organization +relationship: regulates GO:0031505 ! fungal-type cell wall organization + +[Term] +id: GO:0060238 +name: regulation of signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0031137 ! regulation of conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion +relationship: regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion + +[Term] +id: GO:0060239 +name: positive regulation of signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +is_a: GO:0060238 ! regulation of signal transduction involved in conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion +relationship: positively_regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion + +[Term] +id: GO:0060240 +name: negative regulation of signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0060238 ! regulation of signal transduction involved in conjugation with cellular fusion +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion +relationship: negatively_regulates GO:0032005 ! signal transduction involved in positive regulation of conjugation with cellular fusion + +[Term] +id: GO:0060241 +name: lysozyme inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan." [GOC:dph] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0003796 ! lysozyme activity + +[Term] +id: GO:0060242 +name: contact inhibition +namespace: biological_process +alt_id: GO:0060246 +alt_id: GO:0060248 +def: "The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation." [GOC:dph, PMID:17376520] +synonym: "detection of cell density by contact stimulus" RELATED [] +synonym: "detection of cell density by contact stimulus involved in contact inhibition" RELATED [] +xref: Wikipedia:Contact_inhibition +is_a: GO:0060245 ! detection of cell density + +[Term] +id: GO:0060243 +name: negative regulation of cell growth involved in contact inhibition +namespace: biological_process +def: "The negative regulation of cell growth in response to increased cell density." [GOC:dph] +is_a: GO:0030308 ! negative regulation of cell growth +intersection_of: GO:0030308 ! negative regulation of cell growth +intersection_of: part_of GO:0060242 ! contact inhibition +relationship: part_of GO:0060242 ! contact inhibition + +[Term] +id: GO:0060244 +name: negative regulation of cell proliferation involved in contact inhibition +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density." [GOC:dph] +is_a: GO:0008285 ! negative regulation of cell population proliferation +intersection_of: GO:0008285 ! negative regulation of cell population proliferation +intersection_of: part_of GO:0060242 ! contact inhibition +relationship: part_of GO:0060242 ! contact inhibition + +[Term] +id: GO:0060245 +name: detection of cell density +namespace: biological_process +def: "The series of events in which information about the density of cells in a population is received and converted into a molecular signal." [GOC:dph] +is_a: GO:0009595 ! detection of biotic stimulus + +[Term] +id: GO:0060249 +name: anatomical structure homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph] +synonym: "anatomical structure maintenance" EXACT [GOC:dph] +is_a: GO:0042592 ! homeostatic process + +[Term] +id: GO:0060250 +name: germ-line stem-cell niche homeostasis +namespace: biological_process +def: "A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion." [GOC:dph] +synonym: "germ-line stem-cell niche maintenance" EXACT [GOC:dph, GOC:tb] +synonym: "maintenance of germ line stem cell niche" EXACT [GOC:dph] +synonym: "maintenance of germ line stem-cell niche" EXACT [GOC:dph] +synonym: "maintenance of germ-line stem cell niche" EXACT [GOC:dph] +synonym: "maintenance of germ-line stem-cell niche" EXACT [GOC:dph] +is_a: GO:0060249 ! anatomical structure homeostasis + +[Term] +id: GO:0060251 +name: regulation of glial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] +is_a: GO:0014013 ! regulation of gliogenesis +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014009 ! glial cell proliferation +relationship: regulates GO:0014009 ! glial cell proliferation + +[Term] +id: GO:0060252 +name: positive regulation of glial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0014015 ! positive regulation of gliogenesis +is_a: GO:0060251 ! regulation of glial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014009 ! glial cell proliferation +relationship: positively_regulates GO:0014009 ! glial cell proliferation + +[Term] +id: GO:0060253 +name: negative regulation of glial cell proliferation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0014014 ! negative regulation of gliogenesis +is_a: GO:0060251 ! regulation of glial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014009 ! glial cell proliferation +relationship: negatively_regulates GO:0014009 ! glial cell proliferation + +[Term] +id: GO:0060254 +name: regulation of N-terminal protein palmitoylation +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb] +is_a: GO:1903059 ! regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006500 ! N-terminal protein palmitoylation +relationship: regulates GO:0006500 ! N-terminal protein palmitoylation + +[Term] +id: GO:0060255 +name: regulation of macromolecule metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043170 ! macromolecule metabolic process +relationship: regulates GO:0043170 ! macromolecule metabolic process + +[Term] +id: GO:0060256 +name: regulation of flocculation +namespace: biological_process +alt_id: GO:1900455 +def: "Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms." [PMID:10591965, PMID:15466424, PMID:16568252] +synonym: "regulation of flocculation via cell wall protein-carbohydrate interaction" RELATED [] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000128 ! flocculation +relationship: regulates GO:0000128 ! flocculation +created_by: dgf +creation_date: 2012-05-01T05:03:32Z + +[Term] +id: GO:0060257 +name: negative regulation of flocculation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms." [GOC:dph, GOC:tb] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0060256 ! regulation of flocculation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000128 ! flocculation +relationship: negatively_regulates GO:0000128 ! flocculation + +[Term] +id: GO:0060258 +name: negative regulation of filamentous growth +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:dph, GOC:tb] +is_a: GO:0010570 ! regulation of filamentous growth +is_a: GO:0045926 ! negative regulation of growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030447 ! filamentous growth +relationship: negatively_regulates GO:0030447 ! filamentous growth + +[Term] +id: GO:0060259 +name: regulation of feeding behavior +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of feeding behaviour" EXACT [GOC:dph, GOC:tb] +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007631 ! feeding behavior +relationship: regulates GO:0007631 ! feeding behavior + +[Term] +id: GO:0060260 +name: regulation of transcription initiation from RNA polymerase II promoter +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:2000142 ! regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter +relationship: regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter + +[Term] +id: GO:0060261 +name: positive regulation of transcription initiation from RNA polymerase II promoter +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter +is_a: GO:2000144 ! positive regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter +relationship: positively_regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter + +[Term] +id: GO:0060262 +name: negative regulation of N-terminal protein palmitoylation +namespace: biological_process +def: "Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb] +is_a: GO:0060254 ! regulation of N-terminal protein palmitoylation +is_a: GO:1903060 ! negative regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006500 ! N-terminal protein palmitoylation +relationship: negatively_regulates GO:0006500 ! N-terminal protein palmitoylation + +[Term] +id: GO:0060263 +name: regulation of respiratory burst +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045730 ! respiratory burst +relationship: regulates GO:0045730 ! respiratory burst + +[Term] +id: GO:0060264 +name: regulation of respiratory burst involved in inflammatory response +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +synonym: "regulation of respiratory burst involved in acute inflammatory response" BROAD [] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0050727 ! regulation of inflammatory response +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0060263 ! regulation of respiratory burst +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002536 ! respiratory burst involved in inflammatory response +relationship: regulates GO:0002536 ! respiratory burst involved in inflammatory response + +[Term] +id: GO:0060265 +name: positive regulation of respiratory burst involved in inflammatory response +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of respiratory burst involved in acute inflammatory response" BROAD [] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0060264 ! regulation of respiratory burst involved in inflammatory response +is_a: GO:0060267 ! positive regulation of respiratory burst +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002536 ! respiratory burst involved in inflammatory response +relationship: positively_regulates GO:0002536 ! respiratory burst involved in inflammatory response + +[Term] +id: GO:0060266 +name: negative regulation of respiratory burst involved in inflammatory response +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of respiratory burst involved in acute inflammatory response" BROAD [] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060264 ! regulation of respiratory burst involved in inflammatory response +is_a: GO:0060268 ! negative regulation of respiratory burst +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002536 ! respiratory burst involved in inflammatory response +relationship: negatively_regulates GO:0002536 ! respiratory burst involved in inflammatory response + +[Term] +id: GO:0060267 +name: positive regulation of respiratory burst +namespace: biological_process +def: "Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0060263 ! regulation of respiratory burst +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045730 ! respiratory burst +relationship: positively_regulates GO:0045730 ! respiratory burst + +[Term] +id: GO:0060268 +name: negative regulation of respiratory burst +namespace: biological_process +def: "Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GOC:dph, GOC:tb] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0060263 ! regulation of respiratory burst +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045730 ! respiratory burst +relationship: negatively_regulates GO:0045730 ! respiratory burst + +[Term] +id: GO:0060269 +name: centripetally migrating follicle cell migration +namespace: biological_process +def: "The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte." [GOC:dph] +is_a: GO:0007297 ! ovarian follicle cell migration + +[Term] +id: GO:0060270 +name: main body follicle cell migration +namespace: biological_process +def: "The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte." [GOC:dph] +is_a: GO:0007297 ! ovarian follicle cell migration + +[Term] +id: GO:0060271 +name: cilium assembly +namespace: biological_process +alt_id: GO:0042384 +def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441, Reactome:R-HSA-5617833.2] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "ciliogenesis" EXACT [] +synonym: "cilium assembly" EXACT [] +synonym: "cilium biogenesis" RELATED [GOC:mah] +synonym: "cilium formation" EXACT [] +synonym: "cilium morphogenesis" RELATED [] +synonym: "cilium organization" RELATED [GOC:dph] +synonym: "microtubule-based flagellum assembly" EXACT [] +xref: Reactome:R-HSA-5617833.2 +is_a: GO:0044782 ! cilium organization +is_a: GO:0070925 ! organelle assembly +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: has_part GO:0035082 ! axoneme assembly +relationship: has_part GO:0035735 ! intraciliary transport involved in cilium assembly +relationship: has_part GO:0061512 ! protein localization to cilium +relationship: has_part GO:0097712 ! vesicle targeting, trans-Golgi to periciliary membrane compartment +relationship: has_part GO:1905349 ! ciliary transition zone assembly +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +property_value: RO:0002161 NCBITaxon:4890 +property_value: RO:0002161 NCBITaxon:5782 + +[Term] +id: GO:0060272 +name: embryonic skeletal joint morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton." [GOC:bf, GOC:BHF, GOC:dph, UBERON:0000982] +is_a: GO:0048704 ! embryonic skeletal system morphogenesis +relationship: part_of GO:0072498 ! embryonic skeletal joint development + +[Term] +id: GO:0060273 +name: crying behavior +namespace: biological_process +def: "The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli." [GOC:dph] +is_a: GO:0007610 ! behavior + +[Term] +id: GO:0060274 +name: maintenance of stationary phase +namespace: biological_process +def: "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment." [GOC:dph] +is_a: GO:0044764 ! multi-organism cellular process + +[Term] +id: GO:0060275 +name: maintenance of stationary phase in response to starvation +namespace: biological_process +def: "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment." [GOC:dph] +is_a: GO:0042594 ! response to starvation +is_a: GO:0060274 ! maintenance of stationary phase + +[Term] +id: GO:0060276 +name: maintenance of stationary phase in response to toxin +namespace: biological_process +def: "The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment." [GOC:dph] +is_a: GO:0060274 ! maintenance of stationary phase +relationship: part_of GO:0009636 ! response to toxic substance + +[Term] +id: GO:0060277 +name: obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'. +synonym: "negative regulation of transcription from RNA polymerase II promoter during G1 phase of mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of transcription involved in G1 phase of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0071930 + +[Term] +id: GO:0060278 +name: regulation of ovulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030728 ! ovulation +relationship: regulates GO:0030728 ! ovulation + +[Term] +id: GO:0060279 +name: positive regulation of ovulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0060278 ! regulation of ovulation +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030728 ! ovulation +relationship: positively_regulates GO:0030728 ! ovulation + +[Term] +id: GO:0060280 +name: negative regulation of ovulation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060278 ! regulation of ovulation +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030728 ! ovulation +relationship: negatively_regulates GO:0030728 ! ovulation + +[Term] +id: GO:0060281 +name: regulation of oocyte development +namespace: biological_process +def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318] +is_a: GO:1905879 ! regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048599 ! oocyte development +relationship: regulates GO:0048599 ! oocyte development + +[Term] +id: GO:0060282 +name: positive regulation of oocyte development +namespace: biological_process +def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] +is_a: GO:0060281 ! regulation of oocyte development +is_a: GO:1905881 ! positive regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048599 ! oocyte development +relationship: positively_regulates GO:0048599 ! oocyte development + +[Term] +id: GO:0060283 +name: negative regulation of oocyte development +namespace: biological_process +def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] +is_a: GO:0060281 ! regulation of oocyte development +is_a: GO:1905880 ! negative regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048599 ! oocyte development +relationship: negatively_regulates GO:0048599 ! oocyte development + +[Term] +id: GO:0060284 +name: regulation of cell development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048468 ! cell development +relationship: regulates GO:0048468 ! cell development + +[Term] +id: GO:0060285 +name: cilium-dependent cell motility +namespace: biological_process +alt_id: GO:0071974 +def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013] +comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent. +synonym: "ciliary cell motility" RELATED [] +synonym: "cilium cell motility" EXACT [] +synonym: "microtubule-based flagellar cell motility" EXACT [] +is_a: GO:0001539 ! cilium or flagellum-dependent cell motility +relationship: has_part GO:0003341 ! cilium movement + +[Term] +id: GO:0060286 +name: obsolete flagellar cell motility +namespace: biological_process +def: "OBSOLETE. Cell motility due to the motion of one or more flagella." [GOC:dgh, GOC:dph, GOC:mlg] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "flagellar cell motility" EXACT [] +is_obsolete: true +consider: GO:0060285 +consider: GO:0071973 + +[Term] +id: GO:0060287 +name: epithelial cilium movement involved in determination of left/right asymmetry +namespace: biological_process +def: "The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves." [GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, PMID:28559696, PMID:29367579] +synonym: "cilium movement involved in determinationof L/R asymmetry" EXACT [] +synonym: "Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry" NARROW [GOC:cilia] +synonym: "nodal cilium movement involved in determination of left/right asymmetry" NARROW [GOC:cilia] +is_a: GO:0003351 ! epithelial cilium movement involved in extracellular fluid movement +intersection_of: GO:0003351 ! epithelial cilium movement involved in extracellular fluid movement +intersection_of: part_of GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007368 ! determination of left/right symmetry + +[Term] +id: GO:0060288 +name: formation of a compartment boundary +namespace: biological_process +def: "Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier." [GOC:dph] +synonym: "compartment boundary formation" EXACT [] +is_a: GO:0048859 ! formation of anatomical boundary +relationship: part_of GO:0007386 ! compartment pattern specification + +[Term] +id: GO:0060289 +name: compartment boundary maintenance +namespace: biological_process +def: "A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier." [GOC:dph] +is_a: GO:0001894 ! tissue homeostasis +relationship: part_of GO:0007386 ! compartment pattern specification + +[Term] +id: GO:0060290 +name: transdifferentiation +namespace: biological_process +def: "The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate." [GOC:dph, GOC:kmv] +xref: Wikipedia:Transdifferentiation +is_a: GO:0030154 ! cell differentiation + +[Term] +id: GO:0060291 +name: long-term synaptic potentiation +namespace: biological_process +def: "A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse." [GOC:dgh, GOC:dph] +synonym: "long-term potentiation" BROAD [GOC:dph] +synonym: "LTP" RELATED [GOC:dph] +is_a: GO:0048167 ! regulation of synaptic plasticity +is_a: GO:0050806 ! positive regulation of synaptic transmission + +[Term] +id: GO:0060292 +name: long-term synaptic depression +namespace: biological_process +def: "A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse." [GOC:dgh, GOC:dph] +synonym: "long term depression" BROAD [GOC:dph] +synonym: "long term synaptic depression" EXACT [] +synonym: "LTD" RELATED [GOC:dph] +is_a: GO:0048167 ! regulation of synaptic plasticity +is_a: GO:0050805 ! negative regulation of synaptic transmission + +[Term] +id: GO:0060293 +name: germ plasm +namespace: cellular_component +def: "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." [GOC:dph] +xref: Wikipedia:Germ_plasm +is_a: GO:0045495 ! pole plasm + +[Term] +id: GO:0060294 +name: cilium movement involved in cell motility +namespace: biological_process +def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0003341 ! cilium movement +intersection_of: GO:0003341 ! cilium movement +intersection_of: part_of GO:0048870 ! cell motility +relationship: part_of GO:0060285 ! cilium-dependent cell motility + +[Term] +id: GO:0060295 +name: regulation of cilium movement involved in cell motility +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0003352 ! regulation of cilium movement +is_a: GO:1902019 ! regulation of cilium-dependent cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060294 ! cilium movement involved in cell motility +relationship: regulates GO:0060294 ! cilium movement involved in cell motility + +[Term] +id: GO:0060296 +name: regulation of cilium beat frequency involved in ciliary motility +namespace: biological_process +def: "Any process that modulates the frequency of cilium beating involved in ciliary motility." [GOC:BHF, GOC:cilia, GOC:dph, GOC:krc, GOC:tb] +is_a: GO:0003356 ! regulation of cilium beat frequency +is_a: GO:0060295 ! regulation of cilium movement involved in cell motility +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0060297 +name: regulation of sarcomere organization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of sarcomere organisation" EXACT [GOC:mah] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051153 ! regulation of striated muscle cell differentiation +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0110020 ! regulation of actomyosin structure organization +is_a: GO:1902115 ! regulation of organelle assembly +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045214 ! sarcomere organization +relationship: regulates GO:0045214 ! sarcomere organization + +[Term] +id: GO:0060298 +name: positive regulation of sarcomere organization +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0060297 ! regulation of sarcomere organization +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045214 ! sarcomere organization +relationship: positively_regulates GO:0045214 ! sarcomere organization + +[Term] +id: GO:0060299 +name: negative regulation of sarcomere organization +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:0060297 ! regulation of sarcomere organization +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045214 ! sarcomere organization +relationship: negatively_regulates GO:0045214 ! sarcomere organization + +[Term] +id: GO:0060300 +name: regulation of cytokine activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005125 ! cytokine activity +relationship: regulates GO:0005125 ! cytokine activity + +[Term] +id: GO:0060301 +name: positive regulation of cytokine activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0060300 ! regulation of cytokine activity +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005125 ! cytokine activity +relationship: positively_regulates GO:0005125 ! cytokine activity + +[Term] +id: GO:0060302 +name: negative regulation of cytokine activity +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0060300 ! regulation of cytokine activity +is_a: GO:1900121 ! negative regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005125 ! cytokine activity +relationship: negatively_regulates GO:0005125 ! cytokine activity + +[Term] +id: GO:0060303 +name: regulation of nucleosome density +namespace: biological_process +def: "Any process that modulates the number of nucleosomes in a given region of a chromosome." [GOC:dph, GOC:tb] +is_a: GO:0034728 ! nucleosome organization +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0060304 +name: regulation of phosphatidylinositol dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol." [GOC:dph, GOC:tb] +synonym: "regulation of phosphoinositide dephosphorylation" EXACT [] +is_a: GO:0035303 ! regulation of dephosphorylation +is_a: GO:0060255 ! regulation of macromolecule metabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046856 ! phosphatidylinositol dephosphorylation +relationship: regulates GO:0046856 ! phosphatidylinositol dephosphorylation + +[Term] +id: GO:0060305 +name: regulation of cell diameter +namespace: biological_process +def: "Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell." [GOC:dph, GOC:tb] +synonym: "regulation of cell width" BROAD [GOC:dph, GOC:tb] +is_a: GO:0008361 ! regulation of cell size + +[Term] +id: GO:0060306 +name: regulation of membrane repolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +is_a: GO:0034765 ! regulation of ion transmembrane transport +is_a: GO:0042391 ! regulation of membrane potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086009 ! membrane repolarization +relationship: regulates GO:0086009 ! membrane repolarization + +[Term] +id: GO:0060307 +name: regulation of ventricular cardiac muscle cell membrane repolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +synonym: "electrocardiogram T wave" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of ventricular cardiac muscle cell repolarization" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of ventricular cardiac muscle repolarization" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of ventricular cardiomyocyte membrane repolarization" EXACT [] +synonym: "ventricular repolarization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0099623 ! regulation of cardiac muscle cell membrane repolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099625 ! ventricular cardiac muscle cell membrane repolarization +relationship: regulates GO:0099625 ! ventricular cardiac muscle cell membrane repolarization + +[Term] +id: GO:0060308 +name: GTP cyclohydrolase I regulator activity +namespace: molecular_function +def: "Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate." [GOC:dph, GOC:tb] +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0044549 ! GTP cyclohydrolase binding +relationship: regulates GO:0003934 ! GTP cyclohydrolase I activity + +[Term] +id: GO:0060309 +name: elastin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "elastin breakdown" EXACT [] +synonym: "elastin catabolism" EXACT [] +synonym: "elastin degradation" EXACT [] +is_a: GO:0006516 ! glycoprotein catabolic process +is_a: GO:0051541 ! elastin metabolic process + +[Term] +id: GO:0060310 +name: regulation of elastin catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of elastin breakdown" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of elastin catabolism" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of elastin degradation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0042176 ! regulation of protein catabolic process +is_a: GO:1903018 ! regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060309 ! elastin catabolic process +relationship: regulates GO:0060309 ! elastin catabolic process + +[Term] +id: GO:0060311 +name: negative regulation of elastin catabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "down-regulation of elastin catabolic process" EXACT [] +synonym: "negative regulation of elastin breakdown" EXACT [] +synonym: "negative regulation of elastin catabolism" EXACT [] +synonym: "negative regulation of elastin degradation" EXACT [] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0042177 ! negative regulation of protein catabolic process +is_a: GO:0060310 ! regulation of elastin catabolic process +is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060309 ! elastin catabolic process +relationship: negatively_regulates GO:0060309 ! elastin catabolic process + +[Term] +id: GO:0060312 +name: regulation of blood vessel remodeling +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0034103 ! regulation of tissue remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001974 ! blood vessel remodeling +relationship: regulates GO:0001974 ! blood vessel remodeling + +[Term] +id: GO:0060313 +name: negative regulation of blood vessel remodeling +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "down-regulation of blood vessel remodeling" EXACT [GOC:dph, GOC:tb] +synonym: "inhibition of blood vessel remodeling" NARROW [GOC:dph, GOC:tb] +is_a: GO:0034104 ! negative regulation of tissue remodeling +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0060312 ! regulation of blood vessel remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001974 ! blood vessel remodeling +relationship: negatively_regulates GO:0001974 ! blood vessel remodeling + +[Term] +id: GO:0060314 +name: regulation of ryanodine-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity +relationship: regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity + +[Term] +id: GO:0060315 +name: negative regulation of ryanodine-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050849 ! negative regulation of calcium-mediated signaling +is_a: GO:0051280 ! negative regulation of release of sequestered calcium ion into cytosol +is_a: GO:0060314 ! regulation of ryanodine-sensitive calcium-release channel activity +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity +relationship: negatively_regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity + +[Term] +id: GO:0060316 +name: positive regulation of ryanodine-sensitive calcium-release channel activity +namespace: biological_process +def: "Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +is_a: GO:0051281 ! positive regulation of release of sequestered calcium ion into cytosol +is_a: GO:0060314 ! regulation of ryanodine-sensitive calcium-release channel activity +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity +relationship: positively_regulates GO:0005219 ! ryanodine-sensitive calcium-release channel activity + +[Term] +id: GO:0060317 +name: cardiac epithelial to mesenchymal transition +namespace: biological_process +def: "A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, PMID:16314491, PMID:1996351] +synonym: "heart epithelial to mesenchymal transition" EXACT [] +is_a: GO:0001837 ! epithelial to mesenchymal transition +relationship: part_of GO:0003007 ! heart morphogenesis + +[Term] +id: GO:0060318 +name: definitive erythrocyte differentiation +namespace: biological_process +def: "Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis." [GOC:add, GOC:BHF, GOC:dph] +synonym: "definitive erythropoiesis" EXACT [] +synonym: "definitive RBC differentiation" EXACT [CL:0000232] +synonym: "definitive red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0030218 ! erythrocyte differentiation +relationship: part_of GO:0060216 ! definitive hemopoiesis + +[Term] +id: GO:0060319 +name: primitive erythrocyte differentiation +namespace: biological_process +def: "Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis." [GOC:add, GOC:BHF, GOC:dph] +synonym: "primitive erythropoiesis" EXACT [GOC:add, GOC:dph] +synonym: "primitive RBC differentiation" EXACT [CL:0000232] +synonym: "primitive red blood cell differentiation" EXACT [CL:0000232] +is_a: GO:0030218 ! erythrocyte differentiation +relationship: part_of GO:0060215 ! primitive hemopoiesis + +[Term] +id: GO:0060320 +name: rejection of self pollen +namespace: biological_process +def: "The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma." [GOC:dph, GOC:tb] +is_a: GO:0048544 ! recognition of pollen + +[Term] +id: GO:0060321 +name: acceptance of pollen +namespace: biological_process +def: "The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma." [GOC:dph, GOC:tb] +synonym: "acceptance of non-self pollen" RELATED [GOC:dph, GOC:tb] +synonym: "acceptance of self pollen" NARROW [GOC:dph, GOC:tb] +is_a: GO:0048544 ! recognition of pollen + +[Term] +id: GO:0060322 +name: head development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0060323 +name: head morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0010171 ! body morphogenesis +relationship: part_of GO:0060322 ! head development + +[Term] +id: GO:0060324 +name: face development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060322 ! head development + +[Term] +id: GO:0060325 +name: face morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060323 ! head morphogenesis +relationship: part_of GO:0060324 ! face development + +[Term] +id: GO:0060326 +name: cell chemotaxis +namespace: biological_process +def: "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [GOC:dph] +is_a: GO:0006935 ! chemotaxis +is_a: GO:0016477 ! cell migration +relationship: part_of GO:0070887 ! cellular response to chemical stimulus + +[Term] +id: GO:0060327 +name: cytoplasmic actin-based contraction involved in cell motility +namespace: biological_process +def: "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another." [GOC:dph] +is_a: GO:0070252 ! actin-mediated cell contraction +intersection_of: GO:0070252 ! actin-mediated cell contraction +intersection_of: part_of GO:0048870 ! cell motility +relationship: part_of GO:0048870 ! cell motility + +[Term] +id: GO:0060328 +name: cytoplasmic actin-based contraction involved in forward cell motility +namespace: biological_process +def: "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell." [GOC:dph] +synonym: "cytoplasmic actin-based contraction involved in forward cell locomotion" RELATED [] +is_a: GO:0060327 ! cytoplasmic actin-based contraction involved in cell motility + +[Term] +id: GO:0060329 +name: cytoplasmic actin-based contraction involved in rearward cell motility +namespace: biological_process +def: "The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell." [GOC:dph] +synonym: "cytoplasmic actin-based contraction involved in rearward cell locomotion" RELATED [] +is_a: GO:0060327 ! cytoplasmic actin-based contraction involved in cell motility + +[Term] +id: GO:0060330 +name: regulation of response to interferon-gamma +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus." [GOC:dph] +synonym: "regulation of response to gamma-interferon" RELATED [] +synonym: "regulation of response to immune interferon" EXACT [] +synonym: "regulation of response to type II IFN" BROAD [] +synonym: "regulation of response to type II interferon" BROAD [] +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0060759 ! regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034341 ! response to interferon-gamma +relationship: regulates GO:0034341 ! response to interferon-gamma + +[Term] +id: GO:0060331 +name: negative regulation of response to interferon-gamma +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus." [GOC:dph] +synonym: "negative regulation of response to gamma-interferon" RELATED [] +synonym: "negative regulation of response to immune interferon" EXACT [] +synonym: "negative regulation of response to type II IFN" BROAD [] +synonym: "negative regulation of response to type II interferon" BROAD [] +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0060330 ! regulation of response to interferon-gamma +is_a: GO:0060761 ! negative regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034341 ! response to interferon-gamma +relationship: negatively_regulates GO:0034341 ! response to interferon-gamma + +[Term] +id: GO:0060332 +name: positive regulation of response to interferon-gamma +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus." [GOC:dph] +synonym: "positive regulation of response to gamma-interferon" RELATED [] +synonym: "positive regulation of response to immune interferon" EXACT [] +synonym: "positive regulation of response to type II IFN" BROAD [] +synonym: "positive regulation of response to type II interferon" BROAD [] +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0060330 ! regulation of response to interferon-gamma +is_a: GO:0060760 ! positive regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034341 ! response to interferon-gamma +relationship: positively_regulates GO:0034341 ! response to interferon-gamma + +[Term] +id: GO:0060333 +name: interferon-gamma-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far." [GOC:add, GOC:dph, GOC:signaling, PR:000000017] +synonym: "gamma-interferon-mediated signaling pathway" EXACT [GOC:dph] +synonym: "immune interferon signaling pathway" EXACT [GOC:dph] +synonym: "interferon-gamma-mediated signalling pathway" EXACT [GOC:mah] +synonym: "type II IFN-mediated signaling pathway" BROAD [] +synonym: "type II interferon-mediated signaling pathway" BROAD [GOC:dph] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071346 ! cellular response to interferon-gamma + +[Term] +id: GO:0060334 +name: regulation of interferon-gamma-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph] +synonym: "regulation of gamma-interferon-mediated signaling pathway" RELATED [GOC:dph] +synonym: "regulation of immune interferon signaling pathway" EXACT [GOC:dph] +synonym: "regulation of interferon-gamma-mediated signalling pathway" EXACT [GOC:mah] +synonym: "regulation of type II IFN-mediated signaling pathway" BROAD [GOC:dph] +synonym: "regulation of type II interferon-mediated signaling pathway" BROAD [GOC:dph] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +is_a: GO:0060330 ! regulation of response to interferon-gamma +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060333 ! interferon-gamma-mediated signaling pathway +relationship: regulates GO:0060333 ! interferon-gamma-mediated signaling pathway + +[Term] +id: GO:0060335 +name: positive regulation of interferon-gamma-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph] +synonym: "positive regulation of gamma-interferon-mediated signaling pathway" RELATED [GOC:dph] +synonym: "positive regulation of immune interferon-mediated signaling pathway" EXACT [GOC:dph] +synonym: "positive regulation of interferon-gamma-mediated signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of type II IFN-mediated pathway" BROAD [GOC:dph] +synonym: "positive regulation of type II interferon-mediated signaling pathway" BROAD [GOC:dph] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0060332 ! positive regulation of response to interferon-gamma +is_a: GO:0060334 ! regulation of interferon-gamma-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060333 ! interferon-gamma-mediated signaling pathway +relationship: positively_regulates GO:0060333 ! interferon-gamma-mediated signaling pathway + +[Term] +id: GO:0060336 +name: negative regulation of interferon-gamma-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor." [GOC:dph] +synonym: "negative regulation of gamma-interferon-mediated signaling pathway" RELATED [GOC:dph] +synonym: "negative regulation of immune interferon-mediated signaling pathway" EXACT [GOC:dph] +synonym: "negative regulation of interferon-gamma-mediated signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of type II IFN-mediated signaling pathway" BROAD [GOC:dph] +synonym: "negative regulation of type II interferon-mediated signaling pathway" BROAD [GOC:dph] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0060331 ! negative regulation of response to interferon-gamma +is_a: GO:0060334 ! regulation of interferon-gamma-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060333 ! interferon-gamma-mediated signaling pathway +relationship: negatively_regulates GO:0060333 ! interferon-gamma-mediated signaling pathway + +[Term] +id: GO:0060337 +name: type I interferon signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:add, GOC:dph, GOC:signaling, PR:000025848] +synonym: "type I interferon-activated signaling pathway" EXACT [GOC:signaling] +synonym: "type I interferon-mediated signaling pathway" RELATED [GOC:signaling] +synonym: "type I interferon-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071357 ! cellular response to type I interferon + +[Term] +id: GO:0060338 +name: regulation of type I interferon-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph] +synonym: "regulation of type I interferon-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060337 ! type I interferon signaling pathway +relationship: regulates GO:0060337 ! type I interferon signaling pathway + +[Term] +id: GO:0060339 +name: negative regulation of type I interferon-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph] +synonym: "negative regulation of type I interferon-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0060338 ! regulation of type I interferon-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060337 ! type I interferon signaling pathway +relationship: negatively_regulates GO:0060337 ! type I interferon signaling pathway + +[Term] +id: GO:0060340 +name: positive regulation of type I interferon-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor." [GOC:dph] +synonym: "positive regulation of type I interferon-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0060338 ! regulation of type I interferon-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060337 ! type I interferon signaling pathway +relationship: positively_regulates GO:0060337 ! type I interferon signaling pathway + +[Term] +id: GO:0060341 +name: regulation of cellular localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb] +synonym: "regulation of cellular localisation" EXACT [GOC:mah] +is_a: GO:0032879 ! regulation of localization +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051641 ! cellular localization +relationship: regulates GO:0051641 ! cellular localization + +[Term] +id: GO:0060342 +name: photoreceptor inner segment membrane +namespace: cellular_component +def: "The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs." [GOC:dph] +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0001917 ! photoreceptor inner segment + +[Term] +id: GO:0060343 +name: trabecula formation +namespace: biological_process +def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] +synonym: "trabecula biogenesis" RELATED [GOC:dph] +synonym: "trabeculation" EXACT [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0061383 ! trabecula morphogenesis + +[Term] +id: GO:0060344 +name: liver trabecula formation +namespace: biological_process +def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] +synonym: "liver trabecula biogenesis" RELATED [] +synonym: "liver trabeculation" EXACT [GOC:dph] +is_a: GO:0060343 ! trabecula formation +relationship: part_of GO:0001889 ! liver development + +[Term] +id: GO:0060345 +name: spleen trabecula formation +namespace: biological_process +def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] +synonym: "spleen trabecula biogenesis" RELATED [GOC:dph] +synonym: "spleen trabeculation" EXACT [GOC:dph] +is_a: GO:0060343 ! trabecula formation +relationship: part_of GO:0048536 ! spleen development + +[Term] +id: GO:0060346 +name: bone trabecula formation +namespace: biological_process +def: "The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] +synonym: "bone trabecula biogenesis" RELATED [GOC:dph] +synonym: "bone trabeculation" EXACT [GOC:dph] +synonym: "skeletal trabecula biogenesis" RELATED [GOC:dph] +synonym: "skeletal trabecula formation" EXACT [GOC:dph] +synonym: "skeletal trabeculation" EXACT [GOC:dph] +is_a: GO:0060343 ! trabecula formation +relationship: part_of GO:0048705 ! skeletal system morphogenesis +relationship: part_of GO:0061430 ! bone trabecula morphogenesis + +[Term] +id: GO:0060347 +name: heart trabecula formation +namespace: biological_process +def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] +synonym: "cardiac trabecula formation" EXACT [GOC:dph] +synonym: "cardiac trabeculation" EXACT [GOC:dph] +synonym: "heart trabecula biogenesis" RELATED [GOC:dph] +synonym: "heart trabeculation" EXACT [GOC:dph] +is_a: GO:0060343 ! trabecula formation +relationship: part_of GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0061384 ! heart trabecula morphogenesis + +[Term] +id: GO:0060348 +name: bone development +namespace: biological_process +def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0001501 ! skeletal system development + +[Term] +id: GO:0060349 +name: bone morphogenesis +namespace: biological_process +def: "The process in which bones are generated and organized." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0048705 ! skeletal system morphogenesis +relationship: part_of GO:0060348 ! bone development + +[Term] +id: GO:0060350 +name: endochondral bone morphogenesis +namespace: biological_process +def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679] +is_a: GO:0060349 ! bone morphogenesis + +[Term] +id: GO:0060351 +name: cartilage development involved in endochondral bone morphogenesis +namespace: biological_process +def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph] +is_a: GO:0051216 ! cartilage development +intersection_of: GO:0051216 ! cartilage development +intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis +relationship: part_of GO:0060350 ! endochondral bone morphogenesis + +[Term] +id: GO:0060352 +name: cell adhesion molecule production +namespace: biological_process +def: "The appearance of a cell adhesion molecule due to biosynthesis or secretion." [GOC:BHF, GOC:rl] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0060353 +name: regulation of cell adhesion molecule production +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060352 ! cell adhesion molecule production +relationship: regulates GO:0060352 ! cell adhesion molecule production + +[Term] +id: GO:0060354 +name: negative regulation of cell adhesion molecule production +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0060353 ! regulation of cell adhesion molecule production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060352 ! cell adhesion molecule production +relationship: negatively_regulates GO:0060352 ! cell adhesion molecule production + +[Term] +id: GO:0060355 +name: positive regulation of cell adhesion molecule production +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism." [GOC:BHF, GOC:rl] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0060353 ! regulation of cell adhesion molecule production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060352 ! cell adhesion molecule production +relationship: positively_regulates GO:0060352 ! cell adhesion molecule production + +[Term] +id: GO:0060357 +name: regulation of leucine import +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb] +synonym: "regulation of L-leucine import" NARROW [GOC:dph, GOC:tb] +synonym: "regulation of L-leucine uptake" NARROW [GOC:dph, GOC:tb] +synonym: "regulation of leucine uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:1905532 ! regulation of leucine import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903801 ! L-leucine import across plasma membrane +relationship: regulates GO:1903801 ! L-leucine import across plasma membrane + +[Term] +id: GO:0060358 +name: negative regulation of leucine import +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb] +is_a: GO:0060357 ! regulation of leucine import +is_a: GO:1905533 ! negative regulation of leucine import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903801 ! L-leucine import across plasma membrane +relationship: negatively_regulates GO:1903801 ! L-leucine import across plasma membrane + +[Term] +id: GO:0060359 +name: response to ammonium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus." [GOC:dph, GOC:tb] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound + +[Term] +id: GO:0060360 +name: negative regulation of leucine import in response to ammonium ion +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle." [GOC:dph, GOC:tb] +synonym: "negative regulation of leucine uptake in response to ammonium ion" EXACT [] +is_a: GO:0060358 ! negative regulation of leucine import +relationship: part_of GO:0071242 ! cellular response to ammonium ion + +[Term] +id: GO:0060361 +name: flight +namespace: biological_process +def: "Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement." [GOC:dph] +is_a: GO:0040011 ! locomotion + +[Term] +id: GO:0060362 +name: flight involved in flight behavior +namespace: biological_process +def: "Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight." [GOC:dph] +is_a: GO:0031987 ! locomotion involved in locomotory behavior +is_a: GO:0060361 ! flight +intersection_of: GO:0060361 ! flight +intersection_of: part_of GO:0007629 ! flight behavior +relationship: part_of GO:0007629 ! flight behavior + +[Term] +id: GO:0060363 +name: cranial suture morphogenesis +namespace: biological_process +def: "The process in which any suture between cranial bones is generated and organized." [GOC:dph, GOC:pr, GOC:sl] +is_a: GO:0097094 ! craniofacial suture morphogenesis + +[Term] +id: GO:0060364 +name: frontal suture morphogenesis +namespace: biological_process +def: "The process in which the frontal suture is generated and organized." [GOC:dph, GOC:sl] +synonym: "interfrontal suture morphogenesis" EXACT [] +is_a: GO:0060363 ! cranial suture morphogenesis + +[Term] +id: GO:0060365 +name: coronal suture morphogenesis +namespace: biological_process +def: "The process in which the coronal suture is generated and organized." [GOC:dph, GOC:sl] +is_a: GO:0060363 ! cranial suture morphogenesis + +[Term] +id: GO:0060366 +name: lambdoid suture morphogenesis +namespace: biological_process +def: "The process in which the lambdoid suture is generated and organized." [GOC:dph, GOC:sl] +is_a: GO:0060363 ! cranial suture morphogenesis + +[Term] +id: GO:0060367 +name: sagittal suture morphogenesis +namespace: biological_process +def: "The process in which the sagittal suture is generated and organized." [GOC:dph, GOC:sl] +is_a: GO:0060363 ! cranial suture morphogenesis + +[Term] +id: GO:0060368 +name: regulation of Fc receptor mediated stimulatory signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:dph, GOC:tb] +synonym: "regulation of Fc receptor mediated stimulatory signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002431 ! Fc receptor mediated stimulatory signaling pathway +relationship: regulates GO:0002431 ! Fc receptor mediated stimulatory signaling pathway + +[Term] +id: GO:0060369 +name: positive regulation of Fc receptor mediated stimulatory signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of Fc receptor mediated stimulatory signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:0060368 ! regulation of Fc receptor mediated stimulatory signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002431 ! Fc receptor mediated stimulatory signaling pathway +relationship: positively_regulates GO:0002431 ! Fc receptor mediated stimulatory signaling pathway + +[Term] +id: GO:0060370 +name: susceptibility to T cell mediated cytotoxicity +namespace: biological_process +def: "The process of causing a cell to become susceptible to T cell mediated cytotoxicity." [GOC:dph, GOC:tb] +is_a: GO:0001916 ! positive regulation of T cell mediated cytotoxicity + +[Term] +id: GO:0060371 +name: regulation of atrial cardiac muscle cell membrane depolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte." [GOC:dph, GOC:tb] +synonym: "atrial depolarization" RELATED [GOC:dph, GOC:tb] +synonym: "electrocardiogram PR interval" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of atrial cardiac muscle cell depolarization" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of atrial cardiomyocyte membrane depolarization" EXACT [] +is_a: GO:0003254 ! regulation of membrane depolarization + +[Term] +id: GO:0060372 +name: regulation of atrial cardiac muscle cell membrane repolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte." [GOC:dph, GOC:tb] +synonym: "atrial repolarization" RELATED [GOC:dph, GOC:tb] +synonym: "electrocardiogram QRS complex" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of atrial cardiac muscle cell repolarization" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of atrial cardiomyocyte membrane repolarization" EXACT [] +is_a: GO:0099623 ! regulation of cardiac muscle cell membrane repolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099624 ! atrial cardiac muscle cell membrane repolarization +relationship: regulates GO:0099624 ! atrial cardiac muscle cell membrane repolarization + +[Term] +id: GO:0060373 +name: regulation of ventricular cardiac muscle cell membrane depolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte." [GOC:dph, GOC:tb] +synonym: "electrocardiogram QRS complex" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of ventricular cardiomyocyte membrane depolarization" EXACT [] +synonym: "ventricular depolarization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0003254 ! regulation of membrane depolarization + +[Term] +id: GO:0060374 +name: mast cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb] +is_a: GO:0002573 ! myeloid leukocyte differentiation + +[Term] +id: GO:0060375 +name: regulation of mast cell differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb] +is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060374 ! mast cell differentiation +relationship: regulates GO:0060374 ! mast cell differentiation + +[Term] +id: GO:0060376 +name: positive regulation of mast cell differentiation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb] +is_a: GO:0002763 ! positive regulation of myeloid leukocyte differentiation +is_a: GO:0060375 ! regulation of mast cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060374 ! mast cell differentiation +relationship: positively_regulates GO:0060374 ! mast cell differentiation + +[Term] +id: GO:0060377 +name: negative regulation of mast cell differentiation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation." [GOC:dph, GOC:tb] +is_a: GO:0002762 ! negative regulation of myeloid leukocyte differentiation +is_a: GO:0060375 ! regulation of mast cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060374 ! mast cell differentiation +relationship: negatively_regulates GO:0060374 ! mast cell differentiation + +[Term] +id: GO:0060378 +name: regulation of brood size +namespace: biological_process +def: "Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." [GOC:dph, GOC:tb] +is_a: GO:0044703 ! multi-organism reproductive process +is_a: GO:0044706 ! multi-multicellular organism process +is_a: GO:0048609 ! multicellular organismal reproductive process +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0060379 +name: cardiac muscle cell myoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb] +synonym: "cardiac myoblast differentiation" RELATED [GOC:dph, GOC:tb] +synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart] +is_a: GO:0010002 ! cardioblast differentiation +is_a: GO:0045445 ! myoblast differentiation + +[Term] +id: GO:0060380 +name: regulation of single-stranded telomeric DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA." [GOC:dph, GOC:tb] +synonym: "regulation of telomeric ssDNA binding" EXACT [GOC:mah] +is_a: GO:1904742 ! regulation of telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043047 ! single-stranded telomeric DNA binding +relationship: regulates GO:0043047 ! single-stranded telomeric DNA binding + +[Term] +id: GO:0060381 +name: positive regulation of single-stranded telomeric DNA binding +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of telomeric ssDNA binding" EXACT [GOC:mah] +is_a: GO:0060380 ! regulation of single-stranded telomeric DNA binding +is_a: GO:1904744 ! positive regulation of telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043047 ! single-stranded telomeric DNA binding +relationship: positively_regulates GO:0043047 ! single-stranded telomeric DNA binding + +[Term] +id: GO:0060382 +name: regulation of DNA strand elongation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand." [GOC:mah] +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022616 ! DNA strand elongation +relationship: regulates GO:0022616 ! DNA strand elongation + +[Term] +id: GO:0060383 +name: positive regulation of DNA strand elongation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand." [GOC:mah] +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:0060382 ! regulation of DNA strand elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022616 ! DNA strand elongation +relationship: positively_regulates GO:0022616 ! DNA strand elongation + +[Term] +id: GO:0060384 +name: innervation +namespace: biological_process +def: "The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue." [GOC:dph, GOC:sart] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0021675 ! nerve development + +[Term] +id: GO:0060385 +name: axonogenesis involved in innervation +namespace: biological_process +def: "The neurite development process that generates a long process of a neuron, as it invades a target tissue." [GOC:dph, GOC:sart] +is_a: GO:0007409 ! axonogenesis +intersection_of: GO:0007409 ! axonogenesis +intersection_of: part_of GO:0060384 ! innervation +relationship: part_of GO:0060384 ! innervation + +[Term] +id: GO:0060386 +name: synapse assembly involved in innervation +namespace: biological_process +def: "The assembly of a synapse within a target tissue in which a nerve is invading." [GOC:dph, GOC:pr, GOC:sart] +synonym: "synapse biogenesis involved in innervation" EXACT [] +synonym: "synaptogenesis involved in innervation" EXACT [] +is_a: GO:0007416 ! synapse assembly +intersection_of: GO:0007416 ! synapse assembly +intersection_of: part_of GO:0060384 ! innervation +relationship: part_of GO:0060384 ! innervation + +[Term] +id: GO:0060387 +name: fertilization envelope +namespace: cellular_component +def: "A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release." [GOC:dph, ISBN:0878932437] +synonym: "fertilization membrane" RELATED [] +is_a: GO:0035805 ! egg coat + +[Term] +id: GO:0060388 +name: vitelline envelope +namespace: cellular_component +def: "A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization." [GOC:dph, ISBN:0878932437] +synonym: "fertilization membrane" RELATED [] +is_a: GO:0035805 ! egg coat + +[Term] +id: GO:0060389 +name: pathway-restricted SMAD protein phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor." [GOC:dph, ISBN:3527303782] +synonym: "pathway restricted SMAD protein phosphorylation" EXACT [GOC:rl] +synonym: "R-SMAD protein phosphorylation" EXACT [GOC:rl] +synonym: "receptor regulated SMAD protein phosphorylation" EXACT [GOC:rl] +synonym: "receptor-regulated SMAD protein phosphorylation" EXACT [GOC:rl] +is_a: GO:0006468 ! protein phosphorylation +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0060390 +name: regulation of SMAD protein signal transduction +namespace: biological_process +alt_id: GO:0007184 +def: "Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of SMAD protein nuclear translocation" NARROW [GOC:mah] +synonym: "SMAD protein import into nucleus" NARROW [] +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0060395 ! SMAD protein signal transduction +relationship: regulates GO:0060395 ! SMAD protein signal transduction +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0060391 +name: positive regulation of SMAD protein signal transduction +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of SMAD protein import into nucleus" NARROW [] +synonym: "positive regulation of SMAD protein nuclear translocation" NARROW [GOC:mah] +is_a: GO:0060390 ! regulation of SMAD protein signal transduction +is_a: GO:0090100 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0060395 ! SMAD protein signal transduction +relationship: positively_regulates GO:0060395 ! SMAD protein signal transduction + +[Term] +id: GO:0060392 +name: negative regulation of SMAD protein signal transduction +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "negative regulation of SMAD protein import into nucleus" NARROW [] +synonym: "negative regulation of SMAD protein nuclear translocation" NARROW [GOC:mah] +is_a: GO:0060390 ! regulation of SMAD protein signal transduction +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0060395 ! SMAD protein signal transduction +relationship: negatively_regulates GO:0060395 ! SMAD protein signal transduction + +[Term] +id: GO:0060393 +name: regulation of pathway-restricted SMAD protein phosphorylation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation +relationship: regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0060394 +name: negative regulation of pathway-restricted SMAD protein phosphorylation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0060393 ! regulation of pathway-restricted SMAD protein phosphorylation +is_a: GO:0090101 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation +relationship: negatively_regulates GO:0060389 ! pathway-restricted SMAD protein phosphorylation + +[Term] +id: GO:0060395 +name: SMAD protein signal transduction +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0060396 +name: growth hormone receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph, PMID:11445442] +synonym: "cellular response to growth hormone" RELATED [GOC:dph] +synonym: "GH receptor signaling pathway" RELATED [GOC:dph] +synonym: "growth hormone receptor signalling pathway" EXACT [GOC:dph] +is_a: GO:0007169 ! transmembrane receptor protein tyrosine kinase signaling pathway +relationship: part_of GO:0071378 ! cellular response to growth hormone stimulus + +[Term] +id: GO:0060397 +name: growth hormone receptor signaling pathway via JAK-STAT +namespace: biological_process +def: "The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes." [GOC:BHF, GOC:dph, PMID:11445442] +synonym: "JAK-STAT cascade involved in growth hormone signalling pathway" EXACT [GOC:dph] +is_a: GO:0060396 ! growth hormone receptor signaling pathway + +[Term] +id: GO:0060398 +name: regulation of growth hormone receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph] +synonym: "regulation of growth hormone receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060396 ! growth hormone receptor signaling pathway +relationship: regulates GO:0060396 ! growth hormone receptor signaling pathway + +[Term] +id: GO:0060399 +name: positive regulation of growth hormone receptor signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:BHF, GOC:dph] +synonym: "positive regulation of growth hormone receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0060398 ! regulation of growth hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060396 ! growth hormone receptor signaling pathway +relationship: positively_regulates GO:0060396 ! growth hormone receptor signaling pathway + +[Term] +id: GO:0060400 +name: negative regulation of growth hormone receptor signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand." [GOC:dph] +synonym: "negative regulation of growth hormone receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0060398 ! regulation of growth hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060396 ! growth hormone receptor signaling pathway +relationship: negatively_regulates GO:0060396 ! growth hormone receptor signaling pathway + +[Term] +id: GO:0060401 +name: cytosolic calcium ion transport +namespace: biological_process +def: "The directed movement of calcium ions (Ca2+) into, out of or within the cytosol." [GOC:dph, GOC:tb] +is_a: GO:0006816 ! calcium ion transport + +[Term] +id: GO:0060402 +name: calcium ion transport into cytosol +namespace: biological_process +def: "The directed movement of calcium ions (Ca2+) into the cytosol." [GOC:dph, GOC:tb] +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0060401 ! cytosolic calcium ion transport + +[Term] +id: GO:0060404 +name: axonemal microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb] +is_a: GO:0010938 ! cytoplasmic microtubule depolymerization +is_a: GO:0061523 ! cilium disassembly +intersection_of: GO:0007019 ! microtubule depolymerization +intersection_of: occurs_in GO:0005930 ! axoneme +relationship: occurs_in GO:0005930 ! axoneme + +[Term] +id: GO:0060405 +name: regulation of penile erection +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:add, GOC:dph, GOC:tb] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043084 ! penile erection +relationship: regulates GO:0043084 ! penile erection + +[Term] +id: GO:0060406 +name: positive regulation of penile erection +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:dph, GOC:tb] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0060405 ! regulation of penile erection +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043084 ! penile erection +relationship: positively_regulates GO:0043084 ! penile erection + +[Term] +id: GO:0060407 +name: negative regulation of penile erection +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." [GOC:dph, GOC:tb] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060405 ! regulation of penile erection +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043084 ! penile erection +relationship: negatively_regulates GO:0043084 ! penile erection + +[Term] +id: GO:0060408 +name: regulation of acetylcholine metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0033238 ! regulation of cellular amine metabolic process +is_a: GO:0080090 ! regulation of primary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008291 ! acetylcholine metabolic process +relationship: regulates GO:0008291 ! acetylcholine metabolic process + +[Term] +id: GO:0060409 +name: positive regulation of acetylcholine metabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:0060408 ! regulation of acetylcholine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008291 ! acetylcholine metabolic process +relationship: positively_regulates GO:0008291 ! acetylcholine metabolic process + +[Term] +id: GO:0060410 +name: negative regulation of acetylcholine metabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:0060408 ! regulation of acetylcholine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008291 ! acetylcholine metabolic process +relationship: negatively_regulates GO:0008291 ! acetylcholine metabolic process + +[Term] +id: GO:0060411 +name: cardiac septum morphogenesis +namespace: biological_process +alt_id: GO:0003280 +def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart] +synonym: "heart septum morphogenesis" EXACT [] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0003206 ! cardiac chamber morphogenesis +relationship: part_of GO:0003279 ! cardiac septum development + +[Term] +id: GO:0060412 +name: ventricular septum morphogenesis +namespace: biological_process +def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph] +synonym: "interventricular septum morphogenesis" EXACT [GOC:dph] +is_a: GO:0060411 ! cardiac septum morphogenesis +relationship: part_of GO:0003281 ! ventricular septum development + +[Term] +id: GO:0060413 +name: atrial septum morphogenesis +namespace: biological_process +alt_id: GO:0003287 +def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart] +synonym: "interatrial septum morphogenesis" EXACT [GOC:dph] +is_a: GO:0060411 ! cardiac septum morphogenesis +relationship: part_of GO:0003209 ! cardiac atrium morphogenesis +relationship: part_of GO:0003283 ! atrial septum development + +[Term] +id: GO:0060414 +name: aorta smooth muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta] +is_a: GO:0060415 ! muscle tissue morphogenesis +relationship: part_of GO:0035909 ! aorta morphogenesis +relationship: part_of GO:0048745 ! smooth muscle tissue development + +[Term] +id: GO:0060415 +name: muscle tissue morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0048644 ! muscle organ morphogenesis + +[Term] +id: GO:0060416 +name: response to growth hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth." [GOC:BHF, GOC:dph] +synonym: "response to growth hormone stimulus" EXACT [GOC:dos] +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0060417 +name: yolk +namespace: cellular_component +def: "The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo." [GOC:dph, GOC:tb, PMID:18046696] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0060418 +name: yolk plasma +namespace: cellular_component +def: "Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed." [GOC:dph, GOC:tb, PMID:18046696] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0060417 ! yolk + +[Term] +id: GO:0060419 +name: heart growth +namespace: biological_process +def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb] +is_a: GO:0035265 ! organ growth +relationship: part_of GO:0007507 ! heart development + +[Term] +id: GO:0060420 +name: regulation of heart growth +namespace: biological_process +def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb] +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060419 ! heart growth +relationship: regulates GO:0060419 ! heart growth + +[Term] +id: GO:0060421 +name: positive regulation of heart growth +namespace: biological_process +def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0046622 ! positive regulation of organ growth +is_a: GO:0060420 ! regulation of heart growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060419 ! heart growth +relationship: positively_regulates GO:0060419 ! heart growth + +[Term] +id: GO:0060422 +name: peptidyl-dipeptidase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain." [GOC:dph, GOC:tb] +is_a: GO:0030414 ! peptidase inhibitor activity + +[Term] +id: GO:0060423 +name: foregut regionalization +namespace: biological_process +def: "The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place." [GOC:dph, GOC:mtg_lung] +is_a: GO:0009952 ! anterior/posterior pattern specification + +[Term] +id: GO:0060424 +name: lung field specification +namespace: biological_process +def: "The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop." [GOC:dph, GOC:mtg_lung] +synonym: "lung specification" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0010092 ! specification of animal organ identity +is_a: GO:0060423 ! foregut regionalization +relationship: part_of GO:0060431 ! primary lung bud formation + +[Term] +id: GO:0060425 +name: lung morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060426 +name: lung vasculature development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0001944 ! vasculature development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060427 +name: lung connective tissue development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary connective tissue development" EXACT [] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060428 +name: lung epithelium development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060429 +name: epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung] +subset: goslim_drosophila +is_a: GO:0009888 ! tissue development + +[Term] +id: GO:0060430 +name: lung saccule development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells." [GOC:dph, GOC:mtg_lung] +synonym: "lung saccular development" BROAD [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048286 ! lung alveolus development + +[Term] +id: GO:0060431 +name: primary lung bud formation +namespace: biological_process +def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung] +synonym: "lung formation" EXACT [GOC:dph] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0048645 ! animal organ formation +is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis +is_a: GO:0060572 ! morphogenesis of an epithelial bud + +[Term] +id: GO:0060432 +name: lung pattern specification process +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate." [GOC:dph] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060433 +name: bronchus development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] +is_a: GO:0030323 ! respiratory tube development +relationship: part_of GO:0060541 ! respiratory system development + +[Term] +id: GO:0060434 +name: bronchus morphogenesis +namespace: biological_process +def: "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0060433 ! bronchus development + +[Term] +id: GO:0060435 +name: bronchiole development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph, GOC:mtg_lung] +is_a: GO:0030323 ! respiratory tube development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060436 +name: bronchiole morphogenesis +namespace: biological_process +def: "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph] +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0060435 ! bronchiole development + +[Term] +id: GO:0060437 +name: lung growth +namespace: biological_process +def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph] +is_a: GO:0035265 ! organ growth +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060438 +name: trachea development +namespace: biological_process +def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0060541 ! respiratory system development + +[Term] +id: GO:0060439 +name: trachea morphogenesis +namespace: biological_process +def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0060438 ! trachea development + +[Term] +id: GO:0060440 +name: trachea formation +namespace: biological_process +def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] +is_a: GO:0048645 ! animal organ formation +relationship: part_of GO:0060439 ! trachea morphogenesis + +[Term] +id: GO:0060441 +name: epithelial tube branching involved in lung morphogenesis +namespace: biological_process +def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung] +synonym: "lung branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: part_of GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060425 ! lung morphogenesis + +[Term] +id: GO:0060442 +name: branching involved in prostate gland morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph] +synonym: "prostate branching" RELATED [GOC:dph] +synonym: "prostate gland branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0060740 ! prostate gland epithelium morphogenesis +is_a: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0060512 ! prostate gland morphogenesis + +[Term] +id: GO:0060443 +name: mammary gland morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph] +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0030879 ! mammary gland development + +[Term] +id: GO:0060444 +name: branching involved in mammary gland duct morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph] +synonym: "mammary gland branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0060603 ! mammary gland duct morphogenesis +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis + +[Term] +id: GO:0060445 +name: branching involved in salivary gland morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the salivary gland is generated and organized." [GOC:dph] +is_a: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0007435 ! salivary gland morphogenesis +relationship: part_of GO:0007435 ! salivary gland morphogenesis + +[Term] +id: GO:0060446 +name: branching involved in open tracheal system development +namespace: biological_process +def: "The process in which the anatomical structures of branches in the open tracheal system are generated and organized." [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: part_of GO:0007424 ! open tracheal system development +relationship: part_of GO:0007424 ! open tracheal system development + +[Term] +id: GO:0060447 +name: bud outgrowth involved in lung branching +namespace: biological_process +def: "The process in which a region of the lung epithelium initiates an outgrowth." [GOC:dph, GOC:mtg_lung] +synonym: "bud formation involved in lung branching" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0060602 ! branch elongation of an epithelium +relationship: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis + +[Term] +id: GO:0060448 +name: dichotomous subdivision of terminal units involved in lung branching +namespace: biological_process +def: "The process in which a lung bud bifurcates." [GOC:dph, GOC:mtg_lung] +synonym: "bud bifurcation involved in lung branching" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis +relationship: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis + +[Term] +id: GO:0060449 +name: bud elongation involved in lung branching +namespace: biological_process +def: "The process in which a bud in the lung grows out from the point where it is formed." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060602 ! branch elongation of an epithelium +relationship: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis + +[Term] +id: GO:0060450 +name: positive regulation of hindgut contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] +is_a: GO:0043134 ! regulation of hindgut contraction +is_a: GO:0045987 ! positive regulation of smooth muscle contraction +is_a: GO:0060456 ! positive regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043133 ! hindgut contraction +relationship: positively_regulates GO:0043133 ! hindgut contraction + +[Term] +id: GO:0060451 +name: negative regulation of hindgut contraction +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] +is_a: GO:0043134 ! regulation of hindgut contraction +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +is_a: GO:0060457 ! negative regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043133 ! hindgut contraction +relationship: negatively_regulates GO:0043133 ! hindgut contraction + +[Term] +id: GO:0060452 +name: positive regulation of cardiac muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb] +is_a: GO:0045823 ! positive regulation of heart contraction +is_a: GO:0045989 ! positive regulation of striated muscle contraction +is_a: GO:0055117 ! regulation of cardiac muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060048 ! cardiac muscle contraction +relationship: positively_regulates GO:0060048 ! cardiac muscle contraction + +[Term] +id: GO:0060453 +name: regulation of gastric acid secretion +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001696 ! gastric acid secretion +relationship: regulates GO:0001696 ! gastric acid secretion + +[Term] +id: GO:0060454 +name: positive regulation of gastric acid secretion +namespace: biological_process +def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0060453 ! regulation of gastric acid secretion +is_a: GO:0060456 ! positive regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001696 ! gastric acid secretion +relationship: positively_regulates GO:0001696 ! gastric acid secretion + +[Term] +id: GO:0060455 +name: negative regulation of gastric acid secretion +namespace: biological_process +def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0060453 ! regulation of gastric acid secretion +is_a: GO:0060457 ! negative regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001696 ! gastric acid secretion +relationship: negatively_regulates GO:0001696 ! gastric acid secretion + +[Term] +id: GO:0060456 +name: positive regulation of digestive system process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022600 ! digestive system process +relationship: positively_regulates GO:0022600 ! digestive system process + +[Term] +id: GO:0060457 +name: negative regulation of digestive system process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022600 ! digestive system process +relationship: negatively_regulates GO:0022600 ! digestive system process + +[Term] +id: GO:0060458 +name: right lung development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] +synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung] +is_a: GO:0030324 ! lung development + +[Term] +id: GO:0060459 +name: left lung development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] +synonym: "left pulmonary development" EXACT [GOC:dph] +is_a: GO:0030324 ! lung development + +[Term] +id: GO:0060460 +name: left lung morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph] +is_a: GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060459 ! left lung development + +[Term] +id: GO:0060461 +name: right lung morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060458 ! right lung development + +[Term] +id: GO:0060462 +name: lung lobe development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060463 +name: lung lobe morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060462 ! lung lobe development + +[Term] +id: GO:0060464 +name: lung lobe formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060463 ! lung lobe morphogenesis + +[Term] +id: GO:0060465 +name: pharynx development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk] +synonym: "pharyngeal development" RELATED [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048565 ! digestive tract development + +[Term] +id: GO:0060466 +name: activation of meiosis involved in egg activation +namespace: biological_process +def: "Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation." [GOC:dph] +synonym: "reactivation of meiosis after fertilization" NARROW [GOC:dph] +synonym: "resumption of meiosis involved in egg activation" EXACT [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0090427 ! activation of meiosis +intersection_of: GO:0090427 ! activation of meiosis +intersection_of: part_of GO:0007343 ! egg activation +relationship: part_of GO:0007343 ! egg activation + +[Term] +id: GO:0060467 +name: negative regulation of fertilization +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0080154 ! regulation of fertilization +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009566 ! fertilization +relationship: negatively_regulates GO:0009566 ! fertilization + +[Term] +id: GO:0060468 +name: prevention of polyspermy +namespace: biological_process +def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph] +synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph] +synonym: "polyspermy block" EXACT [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0060467 ! negative regulation of fertilization +intersection_of: GO:0060467 ! negative regulation of fertilization +intersection_of: part_of GO:0007343 ! egg activation +relationship: part_of GO:0007343 ! egg activation + +[Term] +id: GO:0060469 +name: positive regulation of transcription involved in egg activation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation." [GOC:dph] +synonym: "activation of the egg genome" RELATED [GOC:dph] +synonym: "activation of the maternal genome" RELATED [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: part_of GO:0007343 ! egg activation +relationship: part_of GO:0007343 ! egg activation + +[Term] +id: GO:0060470 +name: positive regulation of cytosolic calcium ion concentration involved in egg activation +namespace: biological_process +def: "The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg." [GOC:dph] +synonym: "elevation of cytosolic calcium ion concentration involved in egg activation" EXACT [] +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +intersection_of: part_of GO:0007343 ! egg activation +relationship: part_of GO:0007343 ! egg activation + +[Term] +id: GO:0060471 +name: cortical granule exocytosis +namespace: biological_process +def: "The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy." [GOC:dph] +synonym: "cortical granule release" RELATED [GOC:dph] +synonym: "cortical reaction" RELATED [PMID:22088197] +is_a: GO:0017156 ! calcium-ion regulated exocytosis +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0060468 ! prevention of polyspermy + +[Term] +id: GO:0060472 +name: positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol." [GOC:dph] +synonym: "positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration" EXACT [] +is_a: GO:0045956 ! positive regulation of calcium ion-dependent exocytosis +is_a: GO:0050867 ! positive regulation of cell activation +is_a: GO:0060470 ! positive regulation of cytosolic calcium ion concentration involved in egg activation +is_a: GO:1905516 ! positive regulation of fertilization +relationship: positively_regulates GO:0060471 ! cortical granule exocytosis + +[Term] +id: GO:0060473 +name: cortical granule +namespace: cellular_component +def: "A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy." [GOC:dph] +synonym: "cortical vesicle" RELATED [GOC:dph] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0060474 +name: positive regulation of flagellated sperm motility involved in capacitation +namespace: biological_process +def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc] +synonym: "positive regulation of sperm motility involved in capacitation" RELATED [] +is_a: GO:0022414 ! reproductive process +is_a: GO:1902093 ! positive regulation of flagellated sperm motility +intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility +intersection_of: part_of GO:0048240 ! sperm capacitation +relationship: part_of GO:0048240 ! sperm capacitation + +[Term] +id: GO:0060475 +name: positive regulation of actin filament polymerization involved in acrosome reaction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction." [GOC:dph] +synonym: "positive regulation of actin polymerization involved in acrosome reaction" RELATED [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0030838 ! positive regulation of actin filament polymerization +intersection_of: GO:0030838 ! positive regulation of actin filament polymerization +intersection_of: part_of GO:0007340 ! acrosome reaction +relationship: part_of GO:0007340 ! acrosome reaction + +[Term] +id: GO:0060476 +name: protein localization involved in acrosome reaction +namespace: biological_process +def: "The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction." [GOC:dph] +synonym: "protein localisation involved in acrosome reaction" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0030029 ! actin filament-based process +is_a: GO:0034613 ! cellular protein localization +intersection_of: GO:0008104 ! protein localization +intersection_of: part_of GO:0007340 ! acrosome reaction +relationship: part_of GO:0007340 ! acrosome reaction + +[Term] +id: GO:0060477 +name: obsolete peptidyl-serine phosphorylation involved in acrosome reaction +namespace: biological_process +def: "OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction." [GOC:dph] +comment: The reason for obsoletion is that this term does not represent a specific process. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14281 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0060478 +name: acrosomal vesicle exocytosis +namespace: biological_process +def: "The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction." [GOC:dph] +synonym: "acrosomal granule exocytosis" RELATED [GOC:dph] +synonym: "acrosome exocytosis" EXACT [GOC:dph] +is_a: GO:0017156 ! calcium-ion regulated exocytosis +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007340 ! acrosome reaction + +[Term] +id: GO:0060479 +name: lung cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary cell differentiation" EXACT [GOC:dph] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060480 +name: lung goblet cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary goblet cell differentiation" EXACT [] +is_a: GO:0002067 ! glandular epithelial cell differentiation +is_a: GO:0061140 ! lung secretory cell differentiation +relationship: part_of GO:0060481 ! lobar bronchus epithelium development + +[Term] +id: GO:0060481 +name: lobar bronchus epithelium development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060428 ! lung epithelium development +relationship: part_of GO:0060482 ! lobar bronchus development + +[Term] +id: GO:0060482 +name: lobar bronchus development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060433 ! bronchus development + +[Term] +id: GO:0060483 +name: lobar bronchus mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060484 ! lung-associated mesenchyme development +relationship: part_of GO:0060482 ! lobar bronchus development + +[Term] +id: GO:0060484 +name: lung-associated mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung." [GOC:dph, GOC:mtg_lung] +synonym: "lung mesenchyme development" EXACT [GOC:dph] +synonym: "pulmonary mesenchyme development" EXACT [GOC:dph] +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060485 +name: mesenchyme development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph] +synonym: "mesenchymal development" EXACT [GOC:dph] +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0048513 ! animal organ development + +[Term] +id: GO:0060486 +name: club cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles." [GOC:dph, GOC:mtg_lung, PMID:28144783] +synonym: "Clara cell differentiation" EXACT [PMID:28144783] +is_a: GO:0060487 ! lung epithelial cell differentiation + +[Term] +id: GO:0060487 +name: lung epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph] +synonym: "pulmonary epithelial cell differentiation" RELATED [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0060479 ! lung cell differentiation +relationship: part_of GO:0060428 ! lung epithelium development + +[Term] +id: GO:0060488 +name: orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis +namespace: biological_process +def: "The process in which a lung bud bifurcates perpendicular to the plane of the previous bud." [GOC:dph, GOC:mtg_lung] +synonym: "perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0060448 ! dichotomous subdivision of terminal units involved in lung branching + +[Term] +id: GO:0060489 +name: planar dichotomous subdivision of terminal units involved in lung branching morphogenesis +namespace: biological_process +def: "The process in which a lung bud bifurcates parallel to the plane of the previous bud." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060448 ! dichotomous subdivision of terminal units involved in lung branching + +[Term] +id: GO:0060490 +name: lateral sprouting involved in lung morphogenesis +namespace: biological_process +def: "The process in which a branch forms along the side of the lung epithelial tube." [GOC:dph, GOC:mtg_lung] +is_a: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis +relationship: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis + +[Term] +id: GO:0060491 +name: regulation of cell projection assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb] +synonym: "regulation of cell projection formation" RELATED [GOC:dph, GOC:tb] +is_a: GO:0031344 ! regulation of cell projection organization +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030031 ! cell projection assembly +relationship: regulates GO:0030031 ! cell projection assembly + +[Term] +id: GO:0060492 +name: lung induction +namespace: biological_process +def: "The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung." [GOC:dph] +is_a: GO:0001759 ! organ induction +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0061047 ! positive regulation of branching involved in lung morphogenesis +intersection_of: GO:0001759 ! organ induction +intersection_of: positively_regulates GO:0060424 ! lung field specification +relationship: positively_regulates GO:0060424 ! lung field specification + +[Term] +id: GO:0060493 +name: mesenchymal-endodermal cell signaling involved in lung induction +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud." [GOC:dph, GOC:mtg_lung] +synonym: "mesenchymal-endodermal cell signalling involved in lung induction" EXACT [GOC:mah] +is_a: GO:0060494 ! inductive mesenchymal-endodermal cell signaling +is_a: GO:0060496 ! mesenchymal-epithelial cell signaling involved in lung development +is_a: GO:0060497 ! mesenchymal-endodermal cell signaling +intersection_of: GO:0060497 ! mesenchymal-endodermal cell signaling +intersection_of: part_of GO:0060492 ! lung induction +relationship: part_of GO:0060492 ! lung induction + +[Term] +id: GO:0060494 +name: inductive mesenchymal-endodermal cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell." [GOC:dph, GOC:mtg_lung] +synonym: "inductive mesenchymal-endodermal cell signalling" EXACT [GOC:mah] +is_a: GO:0031129 ! inductive cell-cell signaling + +[Term] +id: GO:0060495 +name: cell-cell signaling involved in lung development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung] +synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0030324 ! lung development +relationship: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060496 +name: mesenchymal-epithelial cell signaling involved in lung development +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung] +synonym: "mesenchymal-epithelial cell signalling involved in lung development" EXACT [GOC:mah] +is_a: GO:0060495 ! cell-cell signaling involved in lung development +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling +intersection_of: part_of GO:0030324 ! lung development + +[Term] +id: GO:0060497 +name: mesenchymal-endodermal cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph] +synonym: "mesenchymal-endodermal cell signalling" EXACT [GOC:mah] +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling + +[Term] +id: GO:0060498 +name: retinoic acid receptor signaling pathway involved in lung bud formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud." [GOC:dph, GOC:mtg_lung] +synonym: "retinoic acid receptor signalling pathway involved in lung bud formation" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +relationship: part_of GO:0060431 ! primary lung bud formation + +[Term] +id: GO:0060499 +name: fibroblast growth factor receptor signaling pathway involved in lung induction +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus." [GOC:dph, GOC:mtg_lung] +synonym: "fibroblast growth factor receptor signalling pathway involved in lung induction" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +is_a: GO:0031131 ! reception of an inductive signal +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0060492 ! lung induction +relationship: part_of GO:0060493 ! mesenchymal-endodermal cell signaling involved in lung induction + +[Term] +id: GO:0060500 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed." [GOC:dph, GOC:mtg_lung] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0060501 +name: positive regulation of epithelial cell proliferation involved in lung morphogenesis +namespace: biological_process +def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +relationship: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis + +[Term] +id: GO:0060502 +name: epithelial cell proliferation involved in lung morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph] +is_a: GO:0050673 ! epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060425 ! lung morphogenesis +relationship: part_of GO:0060428 ! lung epithelium development + +[Term] +id: GO:0060503 +name: bud dilation involved in lung branching +namespace: biological_process +def: "The process in which a bud in the lung increases radially." [GOC:dph] +synonym: "bud expansion" EXACT [GOC:dph] +is_a: GO:0003401 ! axis elongation +relationship: part_of GO:0060441 ! epithelial tube branching involved in lung morphogenesis + +[Term] +id: GO:0060504 +name: positive regulation of epithelial cell proliferation involved in lung bud dilation +namespace: biological_process +def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially." [GOC:dph] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0060501 ! positive regulation of epithelial cell proliferation involved in lung morphogenesis +is_a: GO:0061047 ! positive regulation of branching involved in lung morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060505 ! epithelial cell proliferation involved in lung bud dilation +relationship: positively_regulates GO:0060505 ! epithelial cell proliferation involved in lung bud dilation + +[Term] +id: GO:0060505 +name: epithelial cell proliferation involved in lung bud dilation +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud." [GOC:dph] +is_a: GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0060503 ! bud dilation involved in lung branching +relationship: part_of GO:0060503 ! bud dilation involved in lung branching + +[Term] +id: GO:0060506 +name: smoothened signaling pathway involved in lung development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development." [GOC:dph, GOC:mtg_lung] +synonym: "hedgehog signaling pathway involved in lung development" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in lung development" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway involved in lung development" EXACT [GOC:mah] +is_a: GO:0007224 ! smoothened signaling pathway +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0030324 ! lung development +relationship: part_of GO:0060495 ! cell-cell signaling involved in lung development + +[Term] +id: GO:0060507 +name: epidermal growth factor receptor signaling pathway involved in lung development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development." [GOC:dph, GOC:mtg_lung] +synonym: "epidermal growth factor receptor signalling pathway involved in lung development" EXACT [GOC:mah] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +intersection_of: GO:0007173 ! epidermal growth factor receptor signaling pathway +intersection_of: part_of GO:0030324 ! lung development +relationship: part_of GO:0060495 ! cell-cell signaling involved in lung development + +[Term] +id: GO:0060508 +name: lung basal cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary basal cell differentiation" BROAD [GOC:dph, GOC:mtg_lung] +is_a: GO:0060479 ! lung cell differentiation +relationship: part_of GO:0060428 ! lung epithelium development + +[Term] +id: GO:0060509 +name: type I pneumocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles." [GOC:dph, GOC:mtg_lung, ISBN:0721662544] +synonym: "membranous pneumocyte differentiation" EXACT [GOC:dph, ISBN:0721662544] +synonym: "small alveolar cell differentiation" RELATED [GOC:dph, ISBN:0721662544] +synonym: "squamous alveolar cell differentiation" RELATED [GOC:dph, ISBN:0721662544] +is_a: GO:0060487 ! lung epithelial cell differentiation + +[Term] +id: GO:0060510 +name: type II pneumocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies." [GOC:dph, GOC:mtg_lung, ISBN:0721662544] +synonym: "granular pneumocyte differentiation" RELATED [GOC:dph, ISBN:0721662544] +synonym: "great alveolar cell differentiation" EXACT [GOC:dph, ISBN:0721662544] +synonym: "large alveolar cell differentiation" RELATED [GOC:dph, ISBN:0721662544] +is_a: GO:0061140 ! lung secretory cell differentiation + +[Term] +id: GO:0060511 +name: creation of an inductive signal by a mesenchymal cell involved in lung induction +namespace: biological_process +def: "The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud." [GOC:dph, GOC:mtg_lung] +is_a: GO:0031130 ! creation of an inductive signal +relationship: part_of GO:0060493 ! mesenchymal-endodermal cell signaling involved in lung induction + +[Term] +id: GO:0060512 +name: prostate gland morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a prostate gland are generated and organized." [GOC:dph, PMID:18977204] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0030850 ! prostate gland development + +[Term] +id: GO:0060513 +name: prostatic bud formation +namespace: biological_process +def: "The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph, PMID:18977204] +synonym: "primary prostate bud formation" EXACT [GOC:dph] +synonym: "prostate ductal budding" EXACT [GOC:dph, PMID:11401393] +synonym: "prostate gland formation" EXACT [GOC:dph] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0048645 ! animal organ formation +is_a: GO:0060572 ! morphogenesis of an epithelial bud +is_a: GO:0060601 ! lateral sprouting from an epithelium +is_a: GO:0060740 ! prostate gland epithelium morphogenesis + +[Term] +id: GO:0060514 +name: prostate induction +namespace: biological_process +def: "The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland." [GOC:dph, PMID:18977204] +is_a: GO:0001759 ! organ induction +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0060685 ! regulation of prostatic bud formation +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0001759 ! organ induction +intersection_of: positively_regulates GO:0060515 ! prostate field specification +relationship: positively_regulates GO:0060515 ! prostate field specification + +[Term] +id: GO:0060515 +name: prostate field specification +namespace: biological_process +def: "The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop." [GOC:dph, PMID:18977204] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010092 ! specification of animal organ identity +relationship: part_of GO:0060513 ! prostatic bud formation + +[Term] +id: GO:0060516 +name: primary prostatic bud elongation +namespace: biological_process +def: "The increase in size of the prostatic bud as it forms." [GOC:dph, PMID:18977204] +synonym: "prostate bud elongation" BROAD [GOC:dph] +synonym: "prostate bud elongation involved in prostate morphogenesis" EXACT [GOC:dph] +is_a: GO:0060602 ! branch elongation of an epithelium +is_a: GO:0060737 ! prostate gland morphogenetic growth +is_a: GO:0060740 ! prostate gland epithelium morphogenesis + +[Term] +id: GO:0060517 +name: epithelial cell proliferation involved in prostatic bud elongation +namespace: biological_process +def: "The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud." [GOC:dph, PMID:18977204] +is_a: GO:0060767 ! epithelial cell proliferation involved in prostate gland development +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0060516 ! primary prostatic bud elongation +relationship: part_of GO:0060516 ! primary prostatic bud elongation + +[Term] +id: GO:0060518 +name: cell migration involved in prostatic bud elongation +namespace: biological_process +def: "The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204] +is_a: GO:0010631 ! epithelial cell migration +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0060516 ! primary prostatic bud elongation +relationship: part_of GO:0060516 ! primary prostatic bud elongation + +[Term] +id: GO:0060519 +name: cell adhesion involved in prostatic bud elongation +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud." [GOC:dph, PMID:18977204] +is_a: GO:0007155 ! cell adhesion +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0060516 ! primary prostatic bud elongation + +[Term] +id: GO:0060520 +name: activation of prostate induction by androgen receptor signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland." [GOC:dph, GOC:tb, PMID:18977204] +synonym: "activation of prostate induction by androgen receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0030521 ! androgen receptor signaling pathway +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:0060685 ! regulation of prostatic bud formation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000243 ! positive regulation of reproductive process +relationship: positively_regulates GO:0060514 ! prostate induction + +[Term] +id: GO:0060521 +name: mesenchymal-epithelial cell signaling involved in prostate induction +namespace: biological_process +def: "Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate." [GOC:dph, PMID:18977204] +synonym: "mesenchymal-epithelial cell signalling involved in prostate induction" EXACT [GOC:mah] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0060522 ! inductive mesenchymal to epithelial cell signaling +is_a: GO:0060739 ! mesenchymal-epithelial cell signaling involved in prostate gland development +intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling +intersection_of: part_of GO:0060514 ! prostate induction +relationship: part_of GO:0060514 ! prostate induction + +[Term] +id: GO:0060522 +name: inductive mesenchymal to epithelial cell signaling +namespace: biological_process +def: "Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells." [GOC:dph] +synonym: "inductive mesenchymal to epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0031129 ! inductive cell-cell signaling + +[Term] +id: GO:0060523 +name: prostate epithelial cord elongation +namespace: biological_process +def: "The developmental growth process in which solid chords of prostate epithelium increase in length." [GOC:dph, PMID:18977204] +is_a: GO:0060602 ! branch elongation of an epithelium +is_a: GO:0060737 ! prostate gland morphogenetic growth +is_a: GO:0060740 ! prostate gland epithelium morphogenesis +relationship: part_of GO:0060442 ! branching involved in prostate gland morphogenesis + +[Term] +id: GO:0060524 +name: dichotomous subdivision of prostate epithelial cord terminal unit +namespace: biological_process +def: "The process in which a prostate epithelial cord bifurcates at its end." [GOC:dph, PMID:18977204] +synonym: "prostate epithelial cord bifurcation" EXACT [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +relationship: part_of GO:0060442 ! branching involved in prostate gland morphogenesis + +[Term] +id: GO:0060525 +name: prostate glandular acinus development +namespace: biological_process +def: "The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland." [GOC:dph, PMID:18977204] +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0030850 ! prostate gland development + +[Term] +id: GO:0060526 +name: prostate glandular acinus morphogenesis +namespace: biological_process +def: "The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland." [GOC:dph] +is_a: GO:0060740 ! prostate gland epithelium morphogenesis +relationship: part_of GO:0060525 ! prostate glandular acinus development + +[Term] +id: GO:0060527 +name: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis +namespace: biological_process +def: "The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini." [GOC:dph, PMID:18977204] +is_a: GO:0060442 ! branching involved in prostate gland morphogenesis +relationship: part_of GO:0060526 ! prostate glandular acinus morphogenesis + +[Term] +id: GO:0060528 +name: secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate." [GOC:dph, PMID:18977204] +is_a: GO:0002067 ! glandular epithelial cell differentiation +is_a: GO:0060742 ! epithelial cell differentiation involved in prostate gland development +relationship: part_of GO:0060525 ! prostate glandular acinus development + +[Term] +id: GO:0060529 +name: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate." [GOC:dph, PMID:18977204] +is_a: GO:0002067 ! glandular epithelial cell differentiation +is_a: GO:0048863 ! stem cell differentiation +is_a: GO:0060742 ! epithelial cell differentiation involved in prostate gland development +relationship: part_of GO:0060525 ! prostate glandular acinus development + +[Term] +id: GO:0060530 +name: smooth muscle cell differentiation involved in prostate glandular acinus development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus." [GOC:dph, PMID:18977204] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0051145 ! smooth muscle cell differentiation +intersection_of: GO:0051145 ! smooth muscle cell differentiation +intersection_of: part_of GO:0060525 ! prostate glandular acinus development +relationship: part_of GO:0060525 ! prostate glandular acinus development + +[Term] +id: GO:0060531 +name: neuroendocrine cell differentiation involved in prostate gland acinus development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus." [GOC:dph, PMID:18977204] +is_a: GO:0060742 ! epithelial cell differentiation involved in prostate gland development +is_a: GO:0061101 ! neuroendocrine cell differentiation +intersection_of: GO:0061101 ! neuroendocrine cell differentiation +intersection_of: part_of GO:0060525 ! prostate glandular acinus development +relationship: part_of GO:0060525 ! prostate glandular acinus development + +[Term] +id: GO:0060532 +name: bronchus cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph, GOC:mtg_lung] +synonym: "pulmonary cartilage development" EXACT [] +is_a: GO:0051216 ! cartilage development +relationship: part_of GO:0060433 ! bronchus development +created_by: dph +creation_date: 2009-04-10T08:12:06Z + +[Term] +id: GO:0060533 +name: bronchus cartilage morphogenesis +namespace: biological_process +def: "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." [GOC:dph] +is_a: GO:0060536 ! cartilage morphogenesis +relationship: part_of GO:0060434 ! bronchus morphogenesis +relationship: part_of GO:0060532 ! bronchus cartilage development +created_by: dph +creation_date: 2009-04-10T08:47:41Z + +[Term] +id: GO:0060534 +name: trachea cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] +is_a: GO:0051216 ! cartilage development +relationship: part_of GO:0060438 ! trachea development +created_by: dph +creation_date: 2009-04-10T09:00:18Z + +[Term] +id: GO:0060535 +name: trachea cartilage morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cartilage in the trachea are generated and organized." [GOC:dph] +is_a: GO:0060536 ! cartilage morphogenesis +relationship: part_of GO:0060439 ! trachea morphogenesis +relationship: part_of GO:0060534 ! trachea cartilage development +created_by: dph +creation_date: 2009-04-10T09:07:48Z + +[Term] +id: GO:0060536 +name: cartilage morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0051216 ! cartilage development +created_by: dph +creation_date: 2009-04-10T09:13:27Z + +[Term] +id: GO:0060537 +name: muscle tissue development +namespace: biological_process +def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph] +is_a: GO:0009888 ! tissue development +created_by: dph +creation_date: 2009-04-10T08:05:37Z + +[Term] +id: GO:0060538 +name: skeletal muscle organ development +namespace: biological_process +def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph] +is_a: GO:0007517 ! muscle organ development +created_by: dph +creation_date: 2009-04-10T08:25:12Z + +[Term] +id: GO:0060539 +name: diaphragm development +namespace: biological_process +def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph] +is_a: GO:0060538 ! skeletal muscle organ development +relationship: part_of GO:0060541 ! respiratory system development +property_value: RO:0002161 NCBITaxon:8782 +created_by: dph +creation_date: 2009-04-10T08:44:56Z + +[Term] +id: GO:0060540 +name: diaphragm morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph] +is_a: GO:0048644 ! muscle organ morphogenesis +relationship: part_of GO:0060539 ! diaphragm development +property_value: RO:0002161 NCBITaxon:8782 +created_by: dph +creation_date: 2009-04-10T08:47:51Z + +[Term] +id: GO:0060541 +name: respiratory system development +namespace: biological_process +def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph] +subset: goslim_drosophila +is_a: GO:0048731 ! system development +created_by: dph +creation_date: 2009-04-10T08:55:42Z + +[Term] +id: GO:0060542 +name: regulation of strand invasion +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:dph, GOC:tb] +is_a: GO:0000018 ! regulation of DNA recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042148 ! strand invasion +relationship: regulates GO:0042148 ! strand invasion +created_by: dph +creation_date: 2009-04-13T01:28:41Z + +[Term] +id: GO:0060543 +name: negative regulation of strand invasion +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:dph, GOC:elh, GOC:tb] +synonym: "negative regulation of D-loop biosynthesis" RELATED [GOC:elh] +synonym: "negative regulation of D-loop formation" RELATED [GOC:elh] +synonym: "negative regulation of Rad51-mediated strand invasion" EXACT [GOC:elh] +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:0060542 ! regulation of strand invasion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042148 ! strand invasion +relationship: negatively_regulates GO:0042148 ! strand invasion +created_by: dph +creation_date: 2009-04-13T01:32:36Z + +[Term] +id: GO:0060544 +name: regulation of necroptotic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "regulation of necroptosis" NARROW [] +is_a: GO:0062098 ! regulation of programmed necrotic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070266 ! necroptotic process +relationship: regulates GO:0070266 ! necroptotic process +created_by: dph +creation_date: 2009-04-13T01:43:22Z + +[Term] +id: GO:0060545 +name: positive regulation of necroptotic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "positive regulation of necroptosis" NARROW [] +is_a: GO:0060544 ! regulation of necroptotic process +is_a: GO:0062100 ! positive regulation of programmed necrotic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070266 ! necroptotic process +relationship: positively_regulates GO:0070266 ! necroptotic process +created_by: dph +creation_date: 2009-04-13T01:47:27Z + +[Term] +id: GO:0060546 +name: negative regulation of necroptotic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +synonym: "negative regulation of necroptosis" NARROW [] +is_a: GO:0060544 ! regulation of necroptotic process +is_a: GO:0062099 ! negative regulation of programmed necrotic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070266 ! necroptotic process +relationship: negatively_regulates GO:0070266 ! necroptotic process +created_by: dph +creation_date: 2009-04-13T01:49:36Z + +[Term] +id: GO:0060547 +name: negative regulation of necrotic cell death +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010939 ! regulation of necrotic cell death +is_a: GO:0060548 ! negative regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070265 ! necrotic cell death +relationship: negatively_regulates GO:0070265 ! necrotic cell death +created_by: dph +creation_date: 2009-04-13T01:51:25Z + +[Term] +id: GO:0060548 +name: negative regulation of cell death +namespace: biological_process +def: "Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010941 ! regulation of cell death +is_a: GO:0048523 ! negative regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008219 ! cell death +relationship: negatively_regulates GO:0008219 ! cell death +created_by: dph +creation_date: 2009-04-13T01:56:10Z + +[Term] +id: GO:0060549 +name: regulation of fructose 1,6-bisphosphate 1-phosphatase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032113 ! regulation of carbohydrate phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042132 ! fructose 1,6-bisphosphate 1-phosphatase activity +relationship: regulates GO:0042132 ! fructose 1,6-bisphosphate 1-phosphatase activity +created_by: dph +creation_date: 2009-04-13T02:07:32Z + +[Term] +id: GO:0060550 +name: positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:0060549 ! regulation of fructose 1,6-bisphosphate 1-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042132 ! fructose 1,6-bisphosphate 1-phosphatase activity +relationship: positively_regulates GO:0042132 ! fructose 1,6-bisphosphate 1-phosphatase activity +created_by: dph +creation_date: 2009-04-13T02:12:33Z + +[Term] +id: GO:0060551 +name: regulation of fructose 1,6-bisphosphate metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030388 ! fructose 1,6-bisphosphate metabolic process +relationship: regulates GO:0030388 ! fructose 1,6-bisphosphate metabolic process +created_by: dph +creation_date: 2009-04-13T02:20:04Z + +[Term] +id: GO:0060552 +name: positive regulation of fructose 1,6-bisphosphate metabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +is_a: GO:0060551 ! regulation of fructose 1,6-bisphosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030388 ! fructose 1,6-bisphosphate metabolic process +relationship: positively_regulates GO:0030388 ! fructose 1,6-bisphosphate metabolic process +created_by: dph +creation_date: 2009-04-13T02:23:40Z + +[Term] +id: GO:0060556 +name: regulation of vitamin D biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [CHEBI:27300, GOC:BHF, GOC:mah, ISBN:0471331309] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042368 ! vitamin D biosynthetic process +relationship: regulates GO:0042368 ! vitamin D biosynthetic process +created_by: dph +creation_date: 2009-04-13T02:42:15Z + +[Term] +id: GO:0060557 +name: positive regulation of vitamin D biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)." [CHEBI:27300, GOC:BHF, GOC:mah, ISBN:0471331309] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046136 ! positive regulation of vitamin metabolic process +is_a: GO:0060556 ! regulation of vitamin D biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042368 ! vitamin D biosynthetic process +relationship: positively_regulates GO:0042368 ! vitamin D biosynthetic process +created_by: dph +creation_date: 2009-04-13T02:46:14Z + +[Term] +id: GO:0060558 +name: regulation of calcidiol 1-monooxygenase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032768 ! regulation of monooxygenase activity +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0060556 ! regulation of vitamin D biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004498 ! calcidiol 1-monooxygenase activity +relationship: regulates GO:0004498 ! calcidiol 1-monooxygenase activity +created_by: dph +creation_date: 2009-04-13T02:52:18Z + +[Term] +id: GO:0060559 +name: positive regulation of calcidiol 1-monooxygenase activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032770 ! positive regulation of monooxygenase activity +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0060557 ! positive regulation of vitamin D biosynthetic process +is_a: GO:0060558 ! regulation of calcidiol 1-monooxygenase activity +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004498 ! calcidiol 1-monooxygenase activity +relationship: positively_regulates GO:0004498 ! calcidiol 1-monooxygenase activity +created_by: dph +creation_date: 2009-04-13T02:57:28Z + +[Term] +id: GO:0060560 +name: developmental growth involved in morphogenesis +namespace: biological_process +def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph] +synonym: "differential growth" EXACT [GOC:dph] +is_a: GO:0048589 ! developmental growth +intersection_of: GO:0048589 ! developmental growth +intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0009653 ! anatomical structure morphogenesis +created_by: dph +creation_date: 2009-04-28T08:42:53Z + +[Term] +id: GO:0060561 +name: apoptotic process involved in morphogenesis +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis] +synonym: "apoptosis involved in development" RELATED [] +synonym: "apoptosis involved in morphogenesis" NARROW [] +synonym: "morphogenetic apoptosis" RELATED [GOC:dph] +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0009653 ! anatomical structure morphogenesis +created_by: dph +creation_date: 2009-04-28T09:17:27Z + +[Term] +id: GO:0060562 +name: epithelial tube morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0035239 ! tube morphogenesis +created_by: dph +creation_date: 2009-04-28T09:33:36Z + +[Term] +id: GO:0060563 +name: neuroepithelial cell differentiation +namespace: biological_process +def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb] +is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation +created_by: dph +creation_date: 2009-04-29T01:50:05Z + +[Term] +id: GO:0060565 +name: obsolete inhibition of APC-Cdc20 complex activity +namespace: biological_process +def: "OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it was not clearly defined and thus used incorrectly in annotation. +synonym: "inhibition of APC activity during mitotic cell cycle" EXACT [GOC:dph, GOC:tb] +synonym: "inhibition of APC-Cdc20 complex activity" EXACT [] +synonym: "inhibition of APC/C activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "inhibition of cyclosome activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "inhibition of mitotic anaphase-promoting complex activity" RELATED [GOC:vw] +is_obsolete: true +consider: GO:1990948 +created_by: dph +creation_date: 2009-04-29T02:29:31Z + +[Term] +id: GO:0060566 +name: positive regulation of DNA-templated transcription, termination +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:dph, GOC:tb, GOC:txnOH] +synonym: "positive regulation of DNA-dependent transcription, termination" EXACT [GOC:txnOH] +synonym: "positive regulation of termination of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "positive regulation of transcription termination, DNA-dependent" EXACT [GOC:jh2] +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination +is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006353 ! DNA-templated transcription, termination +relationship: positively_regulates GO:0006353 ! DNA-templated transcription, termination +created_by: dph +creation_date: 2009-04-29T02:54:50Z + +[Term] +id: GO:0060567 +name: negative regulation of DNA-templated transcription, termination +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA." [GOC:dph, GOC:tb, GOC:txnOH] +synonym: "negative regulation of DNA-dependent transcription, termination" EXACT [GOC:txnOH] +synonym: "negative regulation of termination of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "negative regulation of transcription termination, DNA-dependent" EXACT [GOC:jh2] +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006353 ! DNA-templated transcription, termination +relationship: negatively_regulates GO:0006353 ! DNA-templated transcription, termination +created_by: dph +creation_date: 2009-04-29T02:59:12Z + +[Term] +id: GO:0060568 +name: regulation of peptide hormone processing +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0070613 ! regulation of protein processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016486 ! peptide hormone processing +relationship: regulates GO:0016486 ! peptide hormone processing +created_by: dph +creation_date: 2009-04-29T03:16:05Z + +[Term] +id: GO:0060569 +name: positive regulation of peptide hormone processing +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] +is_a: GO:0010954 ! positive regulation of protein processing +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0060568 ! regulation of peptide hormone processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016486 ! peptide hormone processing +relationship: positively_regulates GO:0016486 ! peptide hormone processing +created_by: dph +creation_date: 2009-04-29T03:22:05Z + +[Term] +id: GO:0060570 +name: negative regulation of peptide hormone processing +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone." [GOC:dph, GOC:tb] +is_a: GO:0010955 ! negative regulation of protein processing +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0060568 ! regulation of peptide hormone processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016486 ! peptide hormone processing +relationship: negatively_regulates GO:0016486 ! peptide hormone processing +created_by: dph +creation_date: 2009-04-29T03:24:55Z + +[Term] +id: GO:0060571 +name: morphogenesis of an epithelial fold +namespace: biological_process +def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph] +synonym: "epithelial folding" EXACT [GOC:dph] +synonym: "folding of an epithelial sheet" RELATED [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium +created_by: dph +creation_date: 2009-04-30T09:27:17Z + +[Term] +id: GO:0060572 +name: morphogenesis of an epithelial bud +namespace: biological_process +def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph] +is_a: GO:0060571 ! morphogenesis of an epithelial fold +created_by: dph +creation_date: 2009-04-30T09:38:35Z + +[Term] +id: GO:0060573 +name: cell fate specification involved in pattern specification +namespace: biological_process +def: "The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:dph, GOC:tb] +is_a: GO:0001708 ! cell fate specification +intersection_of: GO:0001708 ! cell fate specification +intersection_of: part_of GO:0007389 ! pattern specification process +relationship: part_of GO:0060581 ! cell fate commitment involved in pattern specification +created_by: dph +creation_date: 2009-05-05T02:19:14Z + +[Term] +id: GO:0060574 +name: intestinal epithelial cell maturation +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147] +is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation +relationship: part_of GO:0060576 ! intestinal epithelial cell development +created_by: dph +creation_date: 2009-05-06T08:10:41Z + +[Term] +id: GO:0060575 +name: intestinal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph] +is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation +relationship: part_of GO:0048565 ! digestive tract development +created_by: dph +creation_date: 2009-05-06T08:17:56Z + +[Term] +id: GO:0060576 +name: intestinal epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0002066 ! columnar/cuboidal epithelial cell development +relationship: part_of GO:0060575 ! intestinal epithelial cell differentiation +created_by: dph +creation_date: 2009-05-06T08:20:24Z + +[Term] +id: GO:0060577 +name: pulmonary vein morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph] +synonym: "pulmonary venous blood vessel morphogenesis" RELATED [GOC:dph] +is_a: GO:0048845 ! venous blood vessel morphogenesis +created_by: dph +creation_date: 2009-05-06T08:44:04Z + +[Term] +id: GO:0060578 +name: superior vena cava morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph] +is_a: GO:0048845 ! venous blood vessel morphogenesis +created_by: dph +creation_date: 2009-05-06T08:47:21Z + +[Term] +id: GO:0060579 +name: ventral spinal cord interneuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses." [GOC:dph] +is_a: GO:0048663 ! neuron fate commitment +is_a: GO:0060581 ! cell fate commitment involved in pattern specification +relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning +relationship: part_of GO:0021514 ! ventral spinal cord interneuron differentiation +created_by: dph +creation_date: 2009-05-07T12:21:13Z + +[Term] +id: GO:0060580 +name: ventral spinal cord interneuron fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses." [GOC:dph] +is_a: GO:0048664 ! neuron fate determination +is_a: GO:0060582 ! cell fate determination involved in pattern specification +relationship: part_of GO:0060579 ! ventral spinal cord interneuron fate commitment +created_by: dph +creation_date: 2009-05-07T12:24:50Z + +[Term] +id: GO:0060581 +name: cell fate commitment involved in pattern specification +namespace: biological_process +def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph] +is_a: GO:0045165 ! cell fate commitment +intersection_of: GO:0045165 ! cell fate commitment +intersection_of: part_of GO:0007389 ! pattern specification process +relationship: part_of GO:0007389 ! pattern specification process +created_by: dph +creation_date: 2009-05-07T12:40:55Z + +[Term] +id: GO:0060582 +name: cell fate determination involved in pattern specification +namespace: biological_process +def: "A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:dph] +is_a: GO:0001709 ! cell fate determination +intersection_of: GO:0001709 ! cell fate determination +intersection_of: part_of GO:0007389 ! pattern specification process +relationship: part_of GO:0060581 ! cell fate commitment involved in pattern specification +created_by: dph +creation_date: 2009-05-07T12:48:08Z + +[Term] +id: GO:0060583 +name: regulation of actin cortical patch localization +namespace: biological_process +def: "Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells." [GOC:dph, GOC:tb] +synonym: "regulation of actin cortical patch localisation" EXACT [GOC:mah] +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051666 ! actin cortical patch localization +relationship: regulates GO:0051666 ! actin cortical patch localization +created_by: dph +creation_date: 2009-05-08T01:58:42Z + +[Term] +id: GO:0060584 +name: regulation of prostaglandin-endoperoxide synthase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "regulation of (PG)H synthase activity" EXACT [EC:1.14.99.1] +synonym: "regulation of fatty acid cyclooxygenase activity" EXACT [EC:1.14.99.1] +synonym: "regulation of PG synthetase activity" EXACT [EC:1.14.99.1] +synonym: "regulation of prostaglandin synthetase activity" EXACT [EC:1.14.99.1] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004666 ! prostaglandin-endoperoxide synthase activity +relationship: regulates GO:0004666 ! prostaglandin-endoperoxide synthase activity +created_by: dph +creation_date: 2009-05-08T02:08:37Z + +[Term] +id: GO:0060585 +name: positive regulation of prostaglandin-endoperoxide synthase activity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of (PG)H synthase activity" EXACT [EC:1.14.99.1] +synonym: "positive regulation of fatty acid cyclooxygenase activity" EXACT [EC:1.14.99.1] +synonym: "positive regulation of PG synthetase activity" EXACT [EC:1.14.99.1] +synonym: "positive regulation of prostaglandin synthetase activity" EXACT [EC:1.14.99.1] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:0060584 ! regulation of prostaglandin-endoperoxide synthase activity +relationship: positively_regulates GO:0004666 ! prostaglandin-endoperoxide synthase activity +created_by: dph +creation_date: 2009-05-08T02:12:34Z + +[Term] +id: GO:0060586 +name: multicellular organismal iron ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism." [GOC:dph, GOC:hjd, GOC:tb] +is_a: GO:0048871 ! multicellular organismal homeostasis +is_a: GO:0055072 ! iron ion homeostasis +created_by: dph +creation_date: 2009-05-08T02:18:21Z + +[Term] +id: GO:0060587 +name: regulation of lipoprotein lipid oxidation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0034442 ! regulation of lipoprotein oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034439 ! lipoprotein lipid oxidation +relationship: regulates GO:0034439 ! lipoprotein lipid oxidation +created_by: dph +creation_date: 2009-05-08T02:27:02Z + +[Term] +id: GO:0060588 +name: negative regulation of lipoprotein lipid oxidation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0034443 ! negative regulation of lipoprotein oxidation +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0060587 ! regulation of lipoprotein lipid oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034439 ! lipoprotein lipid oxidation +relationship: negatively_regulates GO:0034439 ! lipoprotein lipid oxidation +created_by: dph +creation_date: 2009-05-08T02:30:49Z + +[Term] +id: GO:0060589 +name: nucleoside-triphosphatase regulator activity +namespace: molecular_function +def: "Modulates the rate of NTP hydrolysis by a NTPase." [GOC:dph, GOC:tb] +synonym: "NTPase regulator activity" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0017111 ! nucleoside-triphosphatase activity +created_by: dph +creation_date: 2009-05-08T02:49:24Z + +[Term] +id: GO:0060590 +name: ATPase regulator activity +namespace: molecular_function +def: "Modulates the rate of ATP hydrolysis by an ATPase." [GOC:dph, GOC:tb] +is_a: GO:0060589 ! nucleoside-triphosphatase regulator activity +relationship: regulates GO:0016887 ! ATPase activity +created_by: dph +creation_date: 2009-05-08T02:49:24Z + +[Term] +id: GO:0060591 +name: chondroblast differentiation +namespace: biological_process +def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph] +synonym: "chondrocyte progenitor cell differentiation" RELATED [GOC:dph] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0051216 ! cartilage development +created_by: dph +creation_date: 2009-05-11T07:47:36Z + +[Term] +id: GO:0060592 +name: mammary gland formation +namespace: biological_process +def: "The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme." [GOC:dph, PMID:16168142, PMID:17120154] +synonym: "mammary bud formation" RELATED [GOC:dph] +synonym: "mammary line formation" NARROW [GOC:dph] +synonym: "mammary placode formation" NARROW [GOC:dph] +synonym: "mammary sprout formation" RELATED [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060443 ! mammary gland morphogenesis +created_by: dph +creation_date: 2009-05-13T08:47:52Z + +[Term] +id: GO:0060593 +name: Wnt signaling pathway involved in mammary gland specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph, PMID:16168142] +synonym: "Wnt receptor signaling pathway involved in mammary gland specification" EXACT [] +synonym: "Wnt receptor signalling pathway involved in mammary gland specification" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in mammary gland specification" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0060594 ! mammary gland specification +relationship: part_of GO:0060594 ! mammary gland specification +created_by: dph +creation_date: 2009-05-13T09:41:37Z + +[Term] +id: GO:0060594 +name: mammary gland specification +namespace: biological_process +def: "The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph] +synonym: "mammary line specification" RELATED [GOC:dph] +is_a: GO:0010092 ! specification of animal organ identity +is_a: GO:0060592 ! mammary gland formation +created_by: dph +creation_date: 2009-05-13T10:09:10Z + +[Term] +id: GO:0060595 +name: fibroblast growth factor receptor signaling pathway involved in mammary gland specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes." [GOC:dph, PMID:16168142] +synonym: "fibroblast growth factor receptor signalling pathway involved in mammary gland specification" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0060594 ! mammary gland specification +relationship: part_of GO:0060594 ! mammary gland specification +created_by: dph +creation_date: 2009-05-13T10:38:18Z + +[Term] +id: GO:0060596 +name: mammary placode formation +namespace: biological_process +def: "The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper." [GOC:dph, PMID:16168142] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0060592 ! mammary gland formation +created_by: dph +creation_date: 2009-05-13T11:55:20Z + +[Term] +id: GO:0060597 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud." [GOC:dph, PMID:16168142] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2009-05-13T12:04:53Z + +[Term] +id: GO:0060598 +name: dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis +namespace: biological_process +def: "The process in which the terminal end of a mammary duct bifurcates." [GOC:dph, PMID:17120154] +synonym: "primary mammary duct branching" EXACT [GOC:dph] +is_a: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: part_of GO:0060751 ! branch elongation involved in mammary gland duct branching +relationship: part_of GO:0060751 ! branch elongation involved in mammary gland duct branching +created_by: dph +creation_date: 2009-05-13T12:16:29Z + +[Term] +id: GO:0060599 +name: lateral sprouting involved in mammary gland duct morphogenesis +namespace: biological_process +def: "The process in which a branch forms along the side of a mammary duct." [GOC:dph, PMID:17120154] +synonym: "mammary gland duct secondary branching" EXACT [GOC:dph] +is_a: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: part_of GO:0060444 ! branching involved in mammary gland duct morphogenesis +relationship: part_of GO:0060444 ! branching involved in mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-05-13T12:38:06Z + +[Term] +id: GO:0060600 +name: dichotomous subdivision of an epithelial terminal unit +namespace: biological_process +def: "The process in which an epithelial cord, rod or tube bifurcates at its end." [GOC:dph] +synonym: "primary branching of an epithelium" RELATED [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0061138 ! morphogenesis of a branching epithelium +created_by: dph +creation_date: 2009-05-14T02:14:50Z + +[Term] +id: GO:0060601 +name: lateral sprouting from an epithelium +namespace: biological_process +def: "The process in which a branch forms along the side of an epithelium." [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0061138 ! morphogenesis of a branching epithelium +created_by: dph +creation_date: 2009-05-14T02:33:01Z + +[Term] +id: GO:0060602 +name: branch elongation of an epithelium +namespace: biological_process +def: "The growth process in which a branch increases in length from its base to its tip." [GOC:dph] +is_a: GO:0003401 ! axis elongation +relationship: part_of GO:0061138 ! morphogenesis of a branching epithelium +created_by: dph +creation_date: 2009-05-14T02:45:44Z + +[Term] +id: GO:0060603 +name: mammary gland duct morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk." [GOC:dph, PMID:17120154] +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0060443 ! mammary gland morphogenesis +relationship: part_of GO:0061180 ! mammary gland epithelium development +created_by: dph +creation_date: 2009-05-15T09:22:25Z + +[Term] +id: GO:0060604 +name: mammary gland duct cavitation +namespace: biological_process +def: "Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod." [GOC:dph, PMID:17120154] +synonym: "milk duct cavitation" RELATED [GOC:dph] +is_a: GO:0060605 ! tube lumen cavitation +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-05-15T09:34:07Z + +[Term] +id: GO:0060605 +name: tube lumen cavitation +namespace: biological_process +def: "The formation of a lumen by hollowing out a solid rod or cord." [GOC:dph] +is_a: GO:0035148 ! tube formation +created_by: dph +creation_date: 2009-05-15T09:39:49Z + +[Term] +id: GO:0060606 +name: tube closure +namespace: biological_process +def: "Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold." [GOC:dph] +is_a: GO:0035148 ! tube formation +created_by: dph +creation_date: 2009-05-15T09:44:07Z + +[Term] +id: GO:0060607 +name: cell-cell adhesion involved in sealing an epithelial fold +namespace: biological_process +def: "The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube." [GOC:dph] +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0060606 ! tube closure +created_by: dph +creation_date: 2009-05-15T09:48:49Z + +[Term] +id: GO:0060608 +name: cell-cell adhesion involved in neural tube closure +namespace: biological_process +def: "The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube." [GOC:dph] +is_a: GO:0060607 ! cell-cell adhesion involved in sealing an epithelial fold +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0001843 ! neural tube closure +relationship: part_of GO:0001843 ! neural tube closure +created_by: dph +creation_date: 2009-05-15T09:56:14Z + +[Term] +id: GO:0060609 +name: apoptotic process involved in tube lumen cavitation +namespace: biological_process +def: "Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube." [GOC:dph, GOC:mtg_apoptosis] +synonym: "apoptosis involved in tube lumen cavitation" NARROW [] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0060605 ! tube lumen cavitation +relationship: part_of GO:0060605 ! tube lumen cavitation +created_by: dph +creation_date: 2009-05-15T10:05:39Z + +[Term] +id: GO:0060610 +name: mesenchymal cell differentiation involved in mammary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts." [GOC:dph] +synonym: "mammary gland mesenchymal cell differentiation" EXACT [GOC:dph] +is_a: GO:0048762 ! mesenchymal cell differentiation +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0030879 ! mammary gland development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2009-05-15T12:17:06Z + +[Term] +id: GO:0060611 +name: mammary gland fat development +namespace: biological_process +def: "The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts." [GOC:dph] +is_a: GO:0060612 ! adipose tissue development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2009-05-15T12:27:57Z + +[Term] +id: GO:0060612 +name: adipose tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph] +synonym: "adipogenesis" RELATED [GOC:mah, GOC:sl] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0048513 ! animal organ development +created_by: dph +creation_date: 2009-05-15T12:36:28Z + +[Term] +id: GO:0060613 +name: fat pad development +namespace: biological_process +def: "The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue." [GOC:dph] +is_a: GO:0060612 ! adipose tissue development +created_by: dph +creation_date: 2009-05-15T12:42:08Z + +[Term] +id: GO:0060614 +name: negative regulation of mammary gland development in males by androgen receptor signaling pathway +namespace: biological_process +def: "Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell." [GOC:dph] +synonym: "negative regulation of mammary gland development in males by androgen receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0030521 ! androgen receptor signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000026 ! regulation of multicellular organismal development +relationship: negatively_regulates GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2009-05-18T08:34:40Z + +[Term] +id: GO:0060615 +name: mammary gland bud formation +namespace: biological_process +def: "The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis." [GOC:dph, PMID:12558599] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060648 ! mammary gland bud morphogenesis +created_by: dph +creation_date: 2009-05-18T08:43:14Z + +[Term] +id: GO:0060616 +name: mammary gland cord formation +namespace: biological_process +def: "The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad." [GOC:dph, PMID:12558599] +synonym: "mammary gland sprout formation" EXACT [GOC:dph] +is_a: GO:0016331 ! morphogenesis of embryonic epithelium +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0060652 ! mammary gland cord morphogenesis +created_by: dph +creation_date: 2009-05-18T08:57:58Z + +[Term] +id: GO:0060617 +name: positive regulation of mammary placode formation by mesenchymal-epithelial signaling +namespace: biological_process +def: "Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode." [GOC:dph, PMID:12558599] +synonym: "positive regulation of mammary placode formation by mesenchymal-epithelial signalling" EXACT [GOC:mah] +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +relationship: positively_regulates GO:0060596 ! mammary placode formation +created_by: dph +creation_date: 2009-05-18T09:16:07Z + +[Term] +id: GO:0060618 +name: nipple development +namespace: biological_process +def: "The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2009-05-18T09:29:38Z + +[Term] +id: GO:0060619 +name: cell migration involved in mammary placode formation +namespace: biological_process +def: "The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode." [GOC:dph, PMID:12558599] +is_a: GO:0010631 ! epithelial cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0060596 ! mammary placode formation +relationship: part_of GO:0060596 ! mammary placode formation +created_by: dph +creation_date: 2009-05-18T09:41:49Z + +[Term] +id: GO:0060620 +name: regulation of cholesterol import +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032374 ! regulation of cholesterol transport +is_a: GO:2000909 ! regulation of sterol import +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070508 ! cholesterol import +relationship: regulates GO:0070508 ! cholesterol import +created_by: dph +creation_date: 2009-05-18T01:41:08Z + +[Term] +id: GO:0060621 +name: negative regulation of cholesterol import +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032375 ! negative regulation of cholesterol transport +is_a: GO:0060620 ! regulation of cholesterol import +is_a: GO:2000910 ! negative regulation of sterol import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070508 ! cholesterol import +relationship: negatively_regulates GO:0070508 ! cholesterol import +created_by: dph +creation_date: 2009-05-18T01:46:21Z + +[Term] +id: GO:0060622 +name: regulation of ascospore wall beta-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores." [GOC:dph, GOC:tb] +is_a: GO:0034307 ! regulation of ascospore formation +is_a: GO:0090093 ! regulation of fungal-type cell wall beta-glucan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034412 ! ascospore wall beta-glucan biosynthetic process +relationship: regulates GO:0034412 ! ascospore wall beta-glucan biosynthetic process +created_by: dph +creation_date: 2009-05-18T02:01:26Z + +[Term] +id: GO:0060623 +name: regulation of chromosome condensation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb] +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030261 ! chromosome condensation +relationship: regulates GO:0030261 ! chromosome condensation +created_by: dph +creation_date: 2009-05-18T02:12:13Z + +[Term] +id: GO:0060624 +name: regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores." [GOC:dph, GOC:tb] +synonym: "regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD [] +synonym: "regulation of ascospore wall 1,3-beta-glucan biosynthetic process" BROAD [] +is_a: GO:0060622 ! regulation of ascospore wall beta-glucan biosynthetic process +is_a: GO:0090334 ! regulation of cell wall (1->3)-beta-D-glucan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034413 ! ascospore wall (1->3)-beta-D-glucan biosynthetic process +relationship: regulates GO:0034413 ! ascospore wall (1->3)-beta-D-glucan biosynthetic process +created_by: dph +creation_date: 2009-05-18T02:18:10Z + +[Term] +id: GO:0060625 +name: regulation of protein deneddylation +namespace: biological_process +alt_id: GO:0060626 +def: "Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein." [GOC:dph, GOC:tb] +synonym: "regulation of cullin deneddylation" NARROW [] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000338 ! protein deneddylation +relationship: regulates GO:0000338 ! protein deneddylation +created_by: dph +creation_date: 2009-05-18T02:22:07Z + +[Term] +id: GO:0060627 +name: regulation of vesicle-mediated transport +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016192 ! vesicle-mediated transport +relationship: regulates GO:0016192 ! vesicle-mediated transport +created_by: dph +creation_date: 2009-05-18T02:29:43Z + +[Term] +id: GO:0060628 +name: regulation of ER to Golgi vesicle-mediated transport +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi." [GOC:dph, GOC:tb] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +relationship: regulates GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: dph +creation_date: 2009-05-18T02:37:00Z + +[Term] +id: GO:0060629 +name: regulation of homologous chromosome segregation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:dph, GOC:tb] +is_a: GO:0051983 ! regulation of chromosome segregation +is_a: GO:0060631 ! regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045143 ! homologous chromosome segregation +relationship: regulates GO:0045143 ! homologous chromosome segregation +created_by: dph +creation_date: 2009-05-18T02:41:02Z + +[Term] +id: GO:0060630 +name: obsolete regulation of M/G1 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle." [GOC:dph, GOC:mtg_cell_cycle, GOC:tb] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "regulation of M/G1 transition of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: dph +creation_date: 2009-05-18T02:48:58Z + +[Term] +id: GO:0060631 +name: regulation of meiosis I +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [GOC:dph, GOC:tb] +is_a: GO:0040020 ! regulation of meiotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007127 ! meiosis I +relationship: regulates GO:0007127 ! meiosis I +created_by: dph +creation_date: 2009-05-18T02:55:19Z + +[Term] +id: GO:0060632 +name: regulation of microtubule-based movement +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb] +is_a: GO:0032886 ! regulation of microtubule-based process +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007018 ! microtubule-based movement +relationship: regulates GO:0007018 ! microtubule-based movement +created_by: dph +creation_date: 2009-05-18T03:07:02Z + +[Term] +id: GO:0060633 +name: negative regulation of transcription initiation from RNA polymerase II promoter +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter." [GOC:dph, GOC:tb, GOC:txnOH] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter +is_a: GO:2000143 ! negative regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter +relationship: negatively_regulates GO:0006367 ! transcription initiation from RNA polymerase II promoter +created_by: dph +creation_date: 2009-05-18T03:11:26Z + +[Term] +id: GO:0060634 +name: regulation of 4,6-pyruvylated galactose residue biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain." [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051072 ! 4,6-pyruvylated galactose residue biosynthetic process +relationship: regulates GO:0051072 ! 4,6-pyruvylated galactose residue biosynthetic process +created_by: dph +creation_date: 2009-05-18T03:15:39Z + +[Term] +id: GO:0060635 +name: positive regulation of (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans." [GOC:dph, GOC:tb] +synonym: "positive regulation of 1,3-beta-D-glucan biosynthetic process" EXACT [] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0032953 ! regulation of (1->3)-beta-D-glucan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +relationship: positively_regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +created_by: dph +creation_date: 2009-05-18T03:22:44Z + +[Term] +id: GO:0060636 +name: negative regulation of (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans." [GOC:dph, GOC:tb] +synonym: "negative regulation of 1,3-beta-D-glucan biosynthetic process" EXACT [] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0032953 ! regulation of (1->3)-beta-D-glucan biosynthetic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +relationship: negatively_regulates GO:0006075 ! (1->3)-beta-D-glucan biosynthetic process +created_by: dph +creation_date: 2009-05-18T03:24:02Z + +[Term] +id: GO:0060637 +name: positive regulation of lactation by mesenchymal-epithelial cell signaling +namespace: biological_process +def: "The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell." [GOC:dph, PMID:12558599] +synonym: "positive regulation of lactation by mesenchymal-epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +is_a: GO:1903489 ! positive regulation of lactation +created_by: dph +creation_date: 2009-05-19T03:39:24Z + +[Term] +id: GO:0060638 +name: mesenchymal-epithelial cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph] +synonym: "mesenchymal-epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +created_by: dph +creation_date: 2009-05-19T03:59:05Z + +[Term] +id: GO:0060639 +name: positive regulation of salivary gland formation by mesenchymal-epithelial signaling +namespace: biological_process +def: "Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell." [GOC:dph] +synonym: "positive regulation of salivary gland formation by mesenchymal-epithelial signalling" EXACT [GOC:mah] +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +relationship: positively_regulates GO:0007435 ! salivary gland morphogenesis +created_by: dph +creation_date: 2009-05-20T04:26:43Z + +[Term] +id: GO:0060640 +name: positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling +namespace: biological_process +def: "Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud." [GOC:dph] +synonym: "positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling" RELATED [] +synonym: "positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling" EXACT [GOC:mah] +is_a: GO:0042488 ! positive regulation of odontogenesis of dentin-containing tooth +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +created_by: dph +creation_date: 2009-05-20T04:33:52Z + +[Term] +id: GO:0060641 +name: mammary gland duct regression in males +namespace: biological_process +def: "The process in which the epithelium of the mammary duct is destroyed in males." [GOC:dph, PMID:12558599] +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-05-20T04:50:57Z + +[Term] +id: GO:0060642 +name: white fat cell differentiation involved in mammary gland fat development +namespace: biological_process +def: "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole." [GOC:dph, PMID:12558599] +is_a: GO:0050872 ! white fat cell differentiation +intersection_of: GO:0050872 ! white fat cell differentiation +intersection_of: part_of GO:0060611 ! mammary gland fat development +relationship: part_of GO:0060611 ! mammary gland fat development +created_by: dph +creation_date: 2009-05-27T05:50:56Z + +[Term] +id: GO:0060643 +name: epithelial cell differentiation involved in mammary gland bud morphogenesis +namespace: biological_process +def: "The process in which a cell of the mammary placode becomes a cell of the mammary gland bud." [GOC:dph] +is_a: GO:0060644 ! mammary gland epithelial cell differentiation +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0060648 ! mammary gland bud morphogenesis +relationship: part_of GO:0060615 ! mammary gland bud formation +created_by: dph +creation_date: 2009-05-29T07:58:13Z + +[Term] +id: GO:0060644 +name: mammary gland epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland." [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0061180 ! mammary gland epithelium development +created_by: dph +creation_date: 2009-05-29T08:03:07Z + +[Term] +id: GO:0060645 +name: peripheral mammary gland bud epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically." [GOC:dph, PMID:12558599] +is_a: GO:0060643 ! epithelial cell differentiation involved in mammary gland bud morphogenesis +created_by: dph +creation_date: 2009-05-29T08:06:16Z + +[Term] +id: GO:0060646 +name: internal mammary gland bud epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape." [GOC:dph, PMID:12558599] +is_a: GO:0060643 ! epithelial cell differentiation involved in mammary gland bud morphogenesis +created_by: dph +creation_date: 2009-05-29T08:10:48Z + +[Term] +id: GO:0060647 +name: mesenchymal cell condensation involved in mammary fat development +namespace: biological_process +def: "The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development." [GOC:dph, PMID:12558599] +is_a: GO:0098609 ! cell-cell adhesion +intersection_of: GO:0098609 ! cell-cell adhesion +intersection_of: part_of GO:0060611 ! mammary gland fat development +relationship: part_of GO:0060611 ! mammary gland fat development +created_by: dph +creation_date: 2009-05-29T08:33:29Z + +[Term] +id: GO:0060648 +name: mammary gland bud morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord." [GOC:dph, PMID:12558599] +is_a: GO:0060572 ! morphogenesis of an epithelial bud +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-05-29T08:42:22Z + +[Term] +id: GO:0060649 +name: mammary gland bud elongation +namespace: biological_process +def: "The process in which the mammary gland bud grows along its axis." [GOC:dph, PMID:12558599] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0060648 ! mammary gland bud morphogenesis +created_by: dph +creation_date: 2009-05-29T08:50:39Z + +[Term] +id: GO:0060650 +name: epithelial cell proliferation involved in mammary gland bud elongation +namespace: biological_process +def: "The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud." [GOC:dph, PMID:12558599] +is_a: GO:0033598 ! mammary gland epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0060649 ! mammary gland bud elongation +relationship: part_of GO:0060649 ! mammary gland bud elongation +created_by: dph +creation_date: 2009-05-29T08:54:54Z + +[Term] +id: GO:0060651 +name: regulation of epithelial cell proliferation involved in mammary gland bud elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud." [GOC:dph, PMID:12558599] +is_a: GO:0033599 ! regulation of mammary gland epithelial cell proliferation +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060650 ! epithelial cell proliferation involved in mammary gland bud elongation +relationship: regulates GO:0060650 ! epithelial cell proliferation involved in mammary gland bud elongation +created_by: dph +creation_date: 2009-05-29T08:57:18Z + +[Term] +id: GO:0060652 +name: mammary gland cord morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat." [GOC:dph, PMID:12558599] +synonym: "mammary gland sprout morphogenesis" EXACT [GOC:dph] +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-05-29T09:06:56Z + +[Term] +id: GO:0060653 +name: epithelial cell differentiation involved in mammary gland cord morphogenesis +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified." [GOC:dph, PMID:12558599] +synonym: "epithelial cell differentiation involved in mammary gland sprout morphogenesis" RELATED [GOC:dph] +is_a: GO:0060644 ! mammary gland epithelial cell differentiation +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0060652 ! mammary gland cord morphogenesis +relationship: part_of GO:0060652 ! mammary gland cord morphogenesis +created_by: dph +creation_date: 2009-05-29T09:17:16Z + +[Term] +id: GO:0060654 +name: mammary gland cord elongation +namespace: biological_process +def: "The process in which the mammary gland sprout grows along its axis." [GOC:dph, PMID:12558599] +is_a: GO:0060751 ! branch elongation involved in mammary gland duct branching +relationship: part_of GO:0060652 ! mammary gland cord morphogenesis +created_by: dph +creation_date: 2009-05-29T09:26:15Z + +[Term] +id: GO:0060655 +name: branching involved in mammary gland cord morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct." [GOC:dph, PMID:12558599] +is_a: GO:0060444 ! branching involved in mammary gland duct morphogenesis +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0060652 ! mammary gland cord morphogenesis +relationship: part_of GO:0060652 ! mammary gland cord morphogenesis +created_by: dph +creation_date: 2009-05-29T09:29:32Z + +[Term] +id: GO:0060656 +name: regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell." [GOC:dph, PMID:12558599] +synonym: "regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0060762 ! regulation of branching involved in mammary gland duct morphogenesis +relationship: regulates GO:0060655 ! branching involved in mammary gland cord morphogenesis +created_by: dph +creation_date: 2009-05-29T09:34:31Z + +[Term] +id: GO:0060657 +name: regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell." [GOC:dph, PMID:12558599] +synonym: "regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0060762 ! regulation of branching involved in mammary gland duct morphogenesis +relationship: regulates GO:0060654 ! mammary gland cord elongation +created_by: dph +creation_date: 2009-05-29T09:43:08Z + +[Term] +id: GO:0060658 +name: nipple morphogenesis +namespace: biological_process +def: "The process in which the nipple is generated and organized." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060618 ! nipple development +created_by: dph +creation_date: 2009-05-29T10:45:44Z + +[Term] +id: GO:0060659 +name: nipple sheath formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate." [GOC:dph, PMID:12558599] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060658 ! nipple morphogenesis +created_by: dph +creation_date: 2009-05-29T10:48:39Z + +[Term] +id: GO:0060660 +name: epidermis morphogenesis involved in nipple formation +namespace: biological_process +def: "The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection." [GOC:dph, PMID:12558599] +is_a: GO:0048730 ! epidermis morphogenesis +intersection_of: GO:0048730 ! epidermis morphogenesis +intersection_of: part_of GO:0060658 ! nipple morphogenesis +relationship: part_of GO:0060658 ! nipple morphogenesis +created_by: dph +creation_date: 2009-05-29T11:04:04Z + +[Term] +id: GO:0060661 +name: submandibular salivary gland formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed." [GOC:dph, PMID:17336109] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0007435 ! salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T08:07:16Z + +[Term] +id: GO:0060662 +name: salivary gland cavitation +namespace: biological_process +def: "The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland." [GOC:dph] +synonym: "salivary gland invagination" EXACT [] +is_a: GO:0060605 ! tube lumen cavitation +relationship: part_of GO:0007435 ! salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T08:22:55Z + +[Term] +id: GO:0060663 +name: apoptotic process involved in salivary gland cavitation +namespace: biological_process +def: "Any apoptotic process in which the solid core of the gland is hollowed out to form the duct." [GOC:dph, GOC:mtg_apoptosis, PMID:17336109] +synonym: "apoptosis involved in salivary gland cavitation" NARROW [] +is_a: GO:0060609 ! apoptotic process involved in tube lumen cavitation +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0060662 ! salivary gland cavitation +relationship: part_of GO:0060662 ! salivary gland cavitation +created_by: dph +creation_date: 2009-06-01T08:27:16Z + +[Term] +id: GO:0060664 +name: epithelial cell proliferation involved in salivary gland morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland." [GOC:dph, PMID:17336109] +is_a: GO:0050673 ! epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0007435 ! salivary gland morphogenesis +relationship: part_of GO:0007435 ! salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T08:36:13Z + +[Term] +id: GO:0060665 +name: regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium." [GOC:dph, PMID:17336109] +synonym: "regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling" EXACT [GOC:mah] +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +is_a: GO:0060693 ! regulation of branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T08:42:36Z + +[Term] +id: GO:0060666 +name: dichotomous subdivision of terminal units involved in salivary gland branching +namespace: biological_process +def: "The process in which a salivary epithelial cord bifurcates at its end." [GOC:dph] +is_a: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: part_of GO:0060445 ! branching involved in salivary gland morphogenesis +relationship: part_of GO:0060445 ! branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T09:38:40Z + +[Term] +id: GO:0060667 +name: branch elongation involved in salivary gland morphogenesis +namespace: biological_process +def: "The differential growth of the salivary branches along their axis, resulting in the growth of a branch." [GOC:dph] +is_a: GO:0060602 ! branch elongation of an epithelium +intersection_of: GO:0060602 ! branch elongation of an epithelium +intersection_of: part_of GO:0007435 ! salivary gland morphogenesis +relationship: part_of GO:0060445 ! branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T09:42:13Z + +[Term] +id: GO:0060668 +name: regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland." [GOC:dph] +synonym: "regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling" EXACT [GOC:mah] +is_a: GO:0035426 ! extracellular matrix-cell signaling +is_a: GO:0060693 ! regulation of branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-01T09:47:56Z + +[Term] +id: GO:0060669 +name: embryonic placenta morphogenesis +namespace: biological_process +def: "The process in which the embryonic placenta is generated and organized." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-02T09:33:37Z + +[Term] +id: GO:0060670 +name: branching involved in labyrinthine layer morphogenesis +namespace: biological_process +def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0060713 ! labyrinthine layer morphogenesis +relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis +created_by: dph +creation_date: 2009-06-02T10:40:40Z + +[Term] +id: GO:0060671 +name: epithelial cell differentiation involved in embryonic placenta development +namespace: biological_process +def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0001892 ! embryonic placenta development +relationship: part_of GO:0060711 ! labyrinthine layer development +created_by: dph +creation_date: 2009-06-02T11:40:52Z + +[Term] +id: GO:0060672 +name: epithelial cell morphogenesis involved in placental branching +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:16916377] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0003382 ! epithelial cell morphogenesis +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0060670 ! branching involved in labyrinthine layer morphogenesis +relationship: part_of GO:0060671 ! epithelial cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-06-02T12:44:52Z + +[Term] +id: GO:0060673 +name: cell-cell signaling involved in placenta development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377] +synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0001890 ! placenta development +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-02T12:58:03Z + +[Term] +id: GO:0060674 +name: placenta blood vessel development +namespace: biological_process +def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377] +is_a: GO:0001568 ! blood vessel development +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0001890 ! placenta development +created_by: dph +creation_date: 2009-06-02T01:09:43Z + +[Term] +id: GO:0060675 +name: ureteric bud morphogenesis +namespace: biological_process +def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0072171 ! mesonephric tubule morphogenesis +relationship: part_of GO:0001657 ! ureteric bud development +created_by: dph +creation_date: 2009-06-02T01:31:41Z + +[Term] +id: GO:0060676 +name: ureteric bud formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378] +is_a: GO:0072172 ! mesonephric tubule formation +relationship: part_of GO:0060675 ! ureteric bud morphogenesis +created_by: dph +creation_date: 2009-06-02T01:47:23Z + +[Term] +id: GO:0060677 +name: ureteric bud elongation +namespace: biological_process +def: "The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated." [GOC:dph, PMID:16916378] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0060675 ! ureteric bud morphogenesis +created_by: dph +creation_date: 2009-06-02T02:13:29Z + +[Term] +id: GO:0060678 +name: dichotomous subdivision of terminal units involved in ureteric bud branching +namespace: biological_process +def: "The process in which a ureteric bud bifurcates at its end." [GOC:dph, PMID:16916378] +synonym: "bifid subdivision of terminal units involved in ureteric bud branching" EXACT [GOC:dph, PMID:16916378] +is_a: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: GO:0060600 ! dichotomous subdivision of an epithelial terminal unit +intersection_of: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: dph +creation_date: 2009-06-02T02:18:17Z + +[Term] +id: GO:0060679 +name: trifid subdivision of terminal units involved in ureteric bud branching +namespace: biological_process +def: "The process in which a ureteric bud splits into three units at its end." [GOC:dph, PMID:16916378] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: dph +creation_date: 2009-06-02T02:37:42Z + +[Term] +id: GO:0060680 +name: lateral sprouting involved in ureteric bud morphogenesis +namespace: biological_process +def: "The process in which a branch forms along the side of a ureteric bud." [GOC:dph, PMID:16916378] +is_a: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: GO:0060601 ! lateral sprouting from an epithelium +intersection_of: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: dph +creation_date: 2009-06-02T02:44:27Z + +[Term] +id: GO:0060681 +name: branch elongation involved in ureteric bud branching +namespace: biological_process +def: "The growth of a branch of the ureteric bud along its axis." [GOC:dph, PMID:16916378] +is_a: GO:0060602 ! branch elongation of an epithelium +intersection_of: GO:0060602 ! branch elongation of an epithelium +intersection_of: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: part_of GO:0060677 ! ureteric bud elongation +created_by: dph +creation_date: 2009-06-02T02:52:55Z + +[Term] +id: GO:0060682 +name: primary ureteric bud growth +namespace: biological_process +def: "The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema." [GOC:dph, PMID:16916378] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0060677 ! ureteric bud elongation +created_by: dph +creation_date: 2009-06-02T02:56:01Z + +[Term] +id: GO:0060683 +name: regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland." [GOC:dph, PMID:18559345] +synonym: "regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling" EXACT [GOC:mah] +is_a: GO:0060684 ! epithelial-mesenchymal cell signaling +is_a: GO:0060693 ! regulation of branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-03T06:30:56Z + +[Term] +id: GO:0060684 +name: epithelial-mesenchymal cell signaling +namespace: biological_process +def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph] +synonym: "epithelial-mesenchymal cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +created_by: dph +creation_date: 2009-06-03T06:36:46Z + +[Term] +id: GO:0060685 +name: regulation of prostatic bud formation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph] +is_a: GO:0003156 ! regulation of animal organ formation +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060513 ! prostatic bud formation +relationship: regulates GO:0060513 ! prostatic bud formation +created_by: dph +creation_date: 2009-06-05T12:29:26Z + +[Term] +id: GO:0060686 +name: negative regulation of prostatic bud formation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth." [GOC:dph] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0060685 ! regulation of prostatic bud formation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060513 ! prostatic bud formation +relationship: negatively_regulates GO:0060513 ! prostatic bud formation +created_by: dph +creation_date: 2009-06-05T12:35:25Z + +[Term] +id: GO:0060687 +name: regulation of branching involved in prostate gland morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060442 ! branching involved in prostate gland morphogenesis +relationship: regulates GO:0060442 ! branching involved in prostate gland morphogenesis +created_by: dph +creation_date: 2009-06-05T12:37:14Z + +[Term] +id: GO:0060688 +name: regulation of morphogenesis of a branching structure +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001763 ! morphogenesis of a branching structure +relationship: regulates GO:0001763 ! morphogenesis of a branching structure +created_by: dph +creation_date: 2009-06-05T12:41:44Z + +[Term] +id: GO:0060689 +name: cell differentiation involved in salivary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland." [GOC:dph] +is_a: GO:0030154 ! cell differentiation +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0007431 ! salivary gland development +relationship: part_of GO:0007431 ! salivary gland development +created_by: dph +creation_date: 2009-06-08T01:01:35Z + +[Term] +id: GO:0060690 +name: epithelial cell differentiation involved in salivary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland." [GOC:dph] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0060689 ! cell differentiation involved in salivary gland development +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0007431 ! salivary gland development +created_by: dph +creation_date: 2009-06-08T01:04:19Z + +[Term] +id: GO:0060691 +name: epithelial cell maturation involved in salivary gland development +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state." [GOC:dph] +is_a: GO:0002070 ! epithelial cell maturation +intersection_of: GO:0002070 ! epithelial cell maturation +intersection_of: part_of GO:0007431 ! salivary gland development +relationship: part_of GO:0060690 ! epithelial cell differentiation involved in salivary gland development +created_by: dph +creation_date: 2009-06-08T01:06:00Z + +[Term] +id: GO:0060692 +name: mesenchymal cell differentiation involved in salivary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] +is_a: GO:0048762 ! mesenchymal cell differentiation +is_a: GO:0060689 ! cell differentiation involved in salivary gland development +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0007431 ! salivary gland development +created_by: dph +creation_date: 2009-06-08T01:08:44Z + +[Term] +id: GO:0060693 +name: regulation of branching involved in salivary gland morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium." [GOC:dph] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060445 ! branching involved in salivary gland morphogenesis +relationship: regulates GO:0060445 ! branching involved in salivary gland morphogenesis +created_by: dph +creation_date: 2009-06-08T01:14:44Z + +[Term] +id: GO:0060694 +name: regulation of cholesterol transporter activity +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cholesterol transporter activity." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032371 ! regulation of sterol transport +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0110112 ! regulation of lipid transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120020 ! cholesterol transfer activity +relationship: regulates GO:0120020 ! cholesterol transfer activity +created_by: dph +creation_date: 2009-06-08T02:05:27Z + +[Term] +id: GO:0060695 +name: negative regulation of cholesterol transporter activity +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of cholesterol transporter activity." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032375 ! negative regulation of cholesterol transport +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0060694 ! regulation of cholesterol transporter activity +is_a: GO:0110114 ! negative regulation of lipid transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120020 ! cholesterol transfer activity +relationship: negatively_regulates GO:0120020 ! cholesterol transfer activity +created_by: dph +creation_date: 2009-06-08T02:08:34Z + +[Term] +id: GO:0060696 +name: regulation of phospholipid catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009395 ! phospholipid catabolic process +relationship: regulates GO:0009395 ! phospholipid catabolic process +created_by: dph +creation_date: 2009-06-08T02:25:45Z + +[Term] +id: GO:0060697 +name: positive regulation of phospholipid catabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:0060696 ! regulation of phospholipid catabolic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009395 ! phospholipid catabolic process +relationship: positively_regulates GO:0009395 ! phospholipid catabolic process +created_by: dph +creation_date: 2009-06-08T02:28:38Z + +[Term] +id: GO:0060698 +name: endoribonuclease inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb] +is_a: GO:0008428 ! ribonuclease inhibitor activity +relationship: negatively_regulates GO:0004521 ! endoribonuclease activity +relationship: part_of GO:0060702 ! negative regulation of endoribonuclease activity +created_by: dph +creation_date: 2009-06-08T02:37:19Z + +[Term] +id: GO:0060699 +name: regulation of endoribonuclease activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb] +is_a: GO:0060700 ! regulation of ribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004521 ! endoribonuclease activity +relationship: regulates GO:0004521 ! endoribonuclease activity +created_by: dph +creation_date: 2009-06-08T02:43:10Z + +[Term] +id: GO:0060700 +name: regulation of ribonuclease activity +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:dph, GOC:tb] +is_a: GO:0032069 ! regulation of nuclease activity +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004540 ! ribonuclease activity +relationship: regulates GO:0004540 ! ribonuclease activity +created_by: dph +creation_date: 2009-06-08T02:45:46Z + +[Term] +id: GO:0060701 +name: negative regulation of ribonuclease activity +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:dph, GOC:tb] +is_a: GO:0032074 ! negative regulation of nuclease activity +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:0060700 ! regulation of ribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004540 ! ribonuclease activity +relationship: negatively_regulates GO:0004540 ! ribonuclease activity +created_by: dph +creation_date: 2009-06-08T02:49:46Z + +[Term] +id: GO:0060702 +name: negative regulation of endoribonuclease activity +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb] +is_a: GO:0060699 ! regulation of endoribonuclease activity +is_a: GO:0060701 ! negative regulation of ribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004521 ! endoribonuclease activity +relationship: negatively_regulates GO:0004521 ! endoribonuclease activity +created_by: dph +creation_date: 2009-06-08T02:52:27Z + +[Term] +id: GO:0060703 +name: deoxyribonuclease inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of deoxyribonuclease." [GOC:dph, GOC:tb] +synonym: "DNase inhibitor activity" RELATED [GOC:dph, GOC:tb] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004536 ! deoxyribonuclease activity +relationship: part_of GO:0032076 ! negative regulation of deoxyribonuclease activity +created_by: dph +creation_date: 2009-06-08T03:00:35Z + +[Term] +id: GO:0060704 +name: acinar cell differentiation involved in salivary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland." [GOC:dph, GOC:tb] +is_a: GO:0060690 ! epithelial cell differentiation involved in salivary gland development +is_a: GO:0090425 ! acinar cell differentiation +intersection_of: GO:0090425 ! acinar cell differentiation +intersection_of: part_of GO:0007431 ! salivary gland development +created_by: dph +creation_date: 2009-06-09T09:32:46Z + +[Term] +id: GO:0060705 +name: neuron differentiation involved in salivary gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland." [GOC:dph] +is_a: GO:0030182 ! neuron differentiation +is_a: GO:0060689 ! cell differentiation involved in salivary gland development +intersection_of: GO:0030182 ! neuron differentiation +intersection_of: part_of GO:0007431 ! salivary gland development +created_by: dph +creation_date: 2009-06-09T09:35:52Z + +[Term] +id: GO:0060706 +name: cell differentiation involved in embryonic placenta development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0030154 ! cell differentiation +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0001892 ! embryonic placenta development +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-09T10:26:42Z + +[Term] +id: GO:0060707 +name: trophoblast giant cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua." [GOC:dph, PMID:16269175] +is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-06-09T10:32:12Z + +[Term] +id: GO:0060708 +name: spongiotrophoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell." [GOC:dph, PMID:16269175] +synonym: "spongiotrophoblast cell differentiation" EXACT [GOC:cjm] +is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development +relationship: part_of GO:0060712 ! spongiotrophoblast layer development +created_by: dph +creation_date: 2009-06-09T10:38:10Z + +[Term] +id: GO:0060709 +name: glycogen cell differentiation involved in embryonic placenta development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer." [GOC:dph, PMID:16269175] +is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development +relationship: part_of GO:0060712 ! spongiotrophoblast layer development +created_by: dph +creation_date: 2009-06-09T10:41:08Z + +[Term] +id: GO:0060710 +name: chorio-allantoic fusion +namespace: biological_process +def: "The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois." [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis +created_by: dph +creation_date: 2009-06-09T03:24:27Z + +[Term] +id: GO:0060711 +name: labyrinthine layer development +namespace: biological_process +def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph] +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-09T03:27:43Z + +[Term] +id: GO:0060712 +name: spongiotrophoblast layer development +namespace: biological_process +def: "The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state." [GOC:dph] +is_a: GO:0009888 ! tissue development +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-09T03:33:40Z + +[Term] +id: GO:0060713 +name: labyrinthine layer morphogenesis +namespace: biological_process +def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0060669 ! embryonic placenta morphogenesis +relationship: part_of GO:0060711 ! labyrinthine layer development +created_by: dph +creation_date: 2009-06-10T08:10:19Z + +[Term] +id: GO:0060714 +name: labyrinthine layer formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis +created_by: dph +creation_date: 2009-06-10T08:13:14Z + +[Term] +id: GO:0060715 +name: syncytiotrophoblast cell differentiation involved in labyrinthine layer development +namespace: biological_process +def: "The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta." [GOC:dph] +is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development +relationship: part_of GO:0060711 ! labyrinthine layer development +created_by: dph +creation_date: 2009-06-11T08:56:18Z + +[Term] +id: GO:0060716 +name: labyrinthine layer blood vessel development +namespace: biological_process +def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph] +is_a: GO:0048568 ! embryonic organ development +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0060674 ! placenta blood vessel development +relationship: part_of GO:0060711 ! labyrinthine layer development +created_by: dph +creation_date: 2009-06-11T09:04:38Z + +[Term] +id: GO:0060717 +name: chorion development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph] +is_a: GO:1903867 ! extraembryonic membrane development +created_by: dph +creation_date: 2009-06-11T02:37:50Z + +[Term] +id: GO:0060718 +name: chorionic trophoblast cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0060717 ! chorion development +created_by: dph +creation_date: 2009-06-11T02:48:27Z + +[Term] +id: GO:0060719 +name: chorionic trophoblast cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060718 ! chorionic trophoblast cell differentiation +created_by: dph +creation_date: 2009-06-11T02:58:45Z + +[Term] +id: GO:0060720 +name: spongiotrophoblast cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer." [GOC:dph] +is_a: GO:0060722 ! cell proliferation involved in embryonic placenta development +relationship: part_of GO:0090214 ! spongiotrophoblast layer developmental growth +created_by: dph +creation_date: 2009-06-11T09:50:35Z + +[Term] +id: GO:0060721 +name: regulation of spongiotrophoblast cell proliferation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation." [GOC:dph] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0060723 ! regulation of cell proliferation involved in embryonic placenta development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060720 ! spongiotrophoblast cell proliferation +relationship: regulates GO:0060720 ! spongiotrophoblast cell proliferation +created_by: dph +creation_date: 2009-06-11T09:57:27Z + +[Term] +id: GO:0060722 +name: cell proliferation involved in embryonic placenta development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph] +is_a: GO:0008283 ! cell population proliferation +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0001892 ! embryonic placenta development +relationship: part_of GO:0001892 ! embryonic placenta development +created_by: dph +creation_date: 2009-06-12T12:46:04Z + +[Term] +id: GO:0060723 +name: regulation of cell proliferation involved in embryonic placenta development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development +relationship: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development +created_by: dph +creation_date: 2009-06-12T12:50:23Z + +[Term] +id: GO:0060724 +name: coreceptor activity involved in epidermal growth factor receptor signaling pathway +namespace: molecular_function +def: "Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway." [GOC:dph, GOC:tb] +synonym: "coreceptor activity involved in epidermal growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0015026 ! coreceptor activity +intersection_of: GO:0015026 ! coreceptor activity +intersection_of: part_of GO:0007173 ! epidermal growth factor receptor signaling pathway +relationship: part_of GO:0007173 ! epidermal growth factor receptor signaling pathway +created_by: dph +creation_date: 2009-06-12T01:06:08Z + +[Term] +id: GO:0060725 +name: regulation of coreceptor activity +namespace: biological_process +def: "Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity." [GOC:dph, GOC:tb] +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015026 ! coreceptor activity +relationship: regulates GO:0015026 ! coreceptor activity +created_by: dph +creation_date: 2009-06-12T01:20:11Z + +[Term] +id: GO:0060726 +name: regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb] +synonym: "regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of Neu/ErbB-2 receptor activity" NARROW [GOC:dph, GOC:tb] +is_a: GO:0042058 ! regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0060725 ! regulation of coreceptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +relationship: regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +created_by: dph +creation_date: 2009-06-12T01:25:20Z + +[Term] +id: GO:0060727 +name: positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb] +synonym: "positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of Neu/ErbB-2 receptor activity" NARROW [GOC:dph, GOC:tb] +is_a: GO:0045742 ! positive regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0060726 ! regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +relationship: positively_regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +created_by: dph +creation_date: 2009-06-12T01:30:50Z + +[Term] +id: GO:0060728 +name: negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway." [GOC:dph, GOC:tb] +synonym: "negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of Neu/ErbB-2 receptor activity" NARROW [GOC:dph, GOC:tb] +is_a: GO:0042059 ! negative regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0060726 ! regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +relationship: negatively_regulates GO:0060724 ! coreceptor activity involved in epidermal growth factor receptor signaling pathway +created_by: dph +creation_date: 2009-06-12T01:32:38Z + +[Term] +id: GO:0060729 +name: intestinal epithelial structure maintenance +namespace: biological_process +def: "A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "epithelial structure maintenance of intestine" EXACT [GOC:dph, GOC:tb] +synonym: "maintenance of intestinal epithelium" EXACT [GOC:dph, GOC:tb] +is_a: GO:0030277 ! maintenance of gastrointestinal epithelium +created_by: dph +creation_date: 2009-06-12T01:44:52Z + +[Term] +id: GO:0060730 +name: regulation of intestinal epithelial structure maintenance +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060729 ! intestinal epithelial structure maintenance +relationship: regulates GO:0060729 ! intestinal epithelial structure maintenance +created_by: dph +creation_date: 2009-06-12T01:49:34Z + +[Term] +id: GO:0060731 +name: positive regulation of intestinal epithelial structure maintenance +namespace: biological_process +def: "Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium." [GOC:dph, GOC:tb] +is_a: GO:0060456 ! positive regulation of digestive system process +is_a: GO:0060730 ! regulation of intestinal epithelial structure maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060729 ! intestinal epithelial structure maintenance +relationship: positively_regulates GO:0060729 ! intestinal epithelial structure maintenance +created_by: dph +creation_date: 2009-06-12T01:51:50Z + +[Term] +id: GO:0060732 +name: positive regulation of inositol phosphate biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:dph, GOC:tb] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0010919 ! regulation of inositol phosphate biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032958 ! inositol phosphate biosynthetic process +relationship: positively_regulates GO:0032958 ! inositol phosphate biosynthetic process +created_by: dph +creation_date: 2009-06-12T01:58:23Z + +[Term] +id: GO:0060733 +name: regulation of eIF2 alpha phosphorylation by amino acid starvation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation." [GOC:dph, GOC:tb] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0034198 ! cellular response to amino acid starvation +is_a: GO:0080135 ! regulation of cellular response to stress +relationship: regulates GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation +created_by: dph +creation_date: 2009-06-12T02:08:50Z + +[Term] +id: GO:0060734 +name: regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress." [GOC:dph, GOC:tb] +synonym: "regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress" EXACT [] +synonym: "regulation of eIF2 alpha phosphorylation by ER stress" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of ER stress-induced eIF2 alpha phosphorylation" EXACT [GOC:bf] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +relationship: regulates GO:0036492 ! eiF2alpha phosphorylation in response to endoplasmic reticulum stress +created_by: dph +creation_date: 2009-06-12T02:15:16Z + +[Term] +id: GO:0060735 +name: regulation of eIF2 alpha phosphorylation by dsRNA +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA." [GOC:dph, GOC:tb] +synonym: "regulation of eIF2 alpha phosphorylation by double-stranded RNA" EXACT [GOC:dph] +synonym: "regulation of eIF2 alpha phosphorylation by PKR" NARROW [GOC:dph, GOC:tb] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0080135 ! regulation of cellular response to stress +relationship: part_of GO:0071359 ! cellular response to dsRNA +relationship: regulates GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation +created_by: dph +creation_date: 2009-06-12T02:27:14Z + +[Term] +id: GO:0060736 +name: prostate gland growth +namespace: biological_process +def: "The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0035265 ! organ growth +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-06-15T09:21:52Z + +[Term] +id: GO:0060737 +name: prostate gland morphogenetic growth +namespace: biological_process +def: "The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form." [GOC:dph] +synonym: "prostate gland growth involved in morphogenesis" EXACT [GOC:dph] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +is_a: GO:0060736 ! prostate gland growth +intersection_of: GO:0060736 ! prostate gland growth +intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060512 ! prostate gland morphogenesis +created_by: dph +creation_date: 2009-06-15T09:24:40Z + +[Term] +id: GO:0060738 +name: epithelial-mesenchymal signaling involved in prostate gland development +namespace: biological_process +def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time." [GOC:dph] +synonym: "epithelial-mesenchymal signalling involved in prostate gland development" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0060684 ! epithelial-mesenchymal cell signaling +intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-06-15T09:31:31Z + +[Term] +id: GO:0060739 +name: mesenchymal-epithelial cell signaling involved in prostate gland development +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time." [GOC:dph] +synonym: "mesenchymal-epithelial cell signalling involved in prostate gland development" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0060638 ! mesenchymal-epithelial cell signaling +intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-06-15T09:35:08Z + +[Term] +id: GO:0060740 +name: prostate gland epithelium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0060512 ! prostate gland morphogenesis +created_by: dph +creation_date: 2009-06-16T09:23:22Z + +[Term] +id: GO:0060741 +name: prostate gland stromal morphogenesis +namespace: biological_process +def: "The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060512 ! prostate gland morphogenesis +relationship: part_of GO:0061448 ! connective tissue development +created_by: dph +creation_date: 2009-06-16T09:27:01Z + +[Term] +id: GO:0060742 +name: epithelial cell differentiation involved in prostate gland development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0030855 ! epithelial cell differentiation +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-06-16T09:32:34Z + +[Term] +id: GO:0060743 +name: epithelial cell maturation involved in prostate gland development +namespace: biological_process +def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] +synonym: "prostate gland epithelial cell development" EXACT [GOC:dph] +is_a: GO:0002070 ! epithelial cell maturation +is_a: GO:0003006 ! developmental process involved in reproduction +intersection_of: GO:0002070 ! epithelial cell maturation +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0060742 ! epithelial cell differentiation involved in prostate gland development +created_by: dph +creation_date: 2009-06-16T09:34:42Z + +[Term] +id: GO:0060744 +name: mammary gland branching involved in thelarche +namespace: biological_process +def: "The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, PMID:19261859] +synonym: "mammary gland branching involved in puberty" RELATED [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0060444 ! branching involved in mammary gland duct morphogenesis +intersection_of: GO:0060444 ! branching involved in mammary gland duct morphogenesis +intersection_of: part_of GO:0042695 ! thelarche +relationship: part_of GO:0042695 ! thelarche +created_by: dph +creation_date: 2009-06-22T08:12:17Z + +[Term] +id: GO:0060745 +name: mammary gland branching involved in pregnancy +namespace: biological_process +def: "The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy." [GOC:dph, PMID:19261859] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0060135 ! maternal process involved in female pregnancy +is_a: GO:0060444 ! branching involved in mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-06-22T08:25:19Z + +[Term] +id: GO:0060746 +name: parental behavior +namespace: biological_process +def: "A reproductive behavior in which a parent cares for and rears offspring." [GOC:dph] +is_a: GO:0019098 ! reproductive behavior +created_by: dph +creation_date: 2009-06-22T09:05:26Z + +[Term] +id: GO:0060747 +name: oral incubation +namespace: biological_process +def: "A parental behavior in which fertilized eggs are taken into the mouth and held until hatching." [GOC:dph] +is_a: GO:0060746 ! parental behavior +created_by: dph +creation_date: 2009-06-22T09:08:58Z + +[Term] +id: GO:0060748 +name: tertiary branching involved in mammary gland duct morphogenesis +namespace: biological_process +def: "The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy." [GOC:dph, PMID:18614704] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0060745 ! mammary gland branching involved in pregnancy +created_by: dph +creation_date: 2009-06-22T10:44:51Z + +[Term] +id: GO:0060749 +name: mammary gland alveolus development +namespace: biological_process +def: "The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061377 ! mammary gland lobule development +created_by: dph +creation_date: 2009-06-22T10:52:12Z + +[Term] +id: GO:0060750 +name: epithelial cell proliferation involved in mammary gland duct elongation +namespace: biological_process +def: "The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth." [GOC:dph] +is_a: GO:0033598 ! mammary gland epithelial cell proliferation +intersection_of: GO:0033598 ! mammary gland epithelial cell proliferation +intersection_of: part_of GO:0060751 ! branch elongation involved in mammary gland duct branching +relationship: part_of GO:0060751 ! branch elongation involved in mammary gland duct branching +created_by: dph +creation_date: 2009-06-22T10:58:12Z + +[Term] +id: GO:0060751 +name: branch elongation involved in mammary gland duct branching +namespace: biological_process +def: "The developmental growth process in which a branch of a mammary gland duct elongates." [GOC:dph] +synonym: "mammary gland duct branch elongation" EXACT [GOC:dph] +is_a: GO:0060602 ! branch elongation of an epithelium +intersection_of: GO:0060602 ! branch elongation of an epithelium +intersection_of: part_of GO:0060603 ! mammary gland duct morphogenesis +relationship: part_of GO:0060444 ! branching involved in mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-06-22T11:02:44Z + +[Term] +id: GO:0060752 +name: intestinal phytosterol absorption +namespace: biological_process +def: "Any process in which phytosterols are taken up from the contents of the intestine." [GOC:dph, GOC:tb] +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0098856 ! intestinal lipid absorption +created_by: dph +creation_date: 2009-06-22T02:08:43Z + +[Term] +id: GO:0060753 +name: regulation of mast cell chemotaxis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002551 ! mast cell chemotaxis +relationship: regulates GO:0002551 ! mast cell chemotaxis +created_by: dph +creation_date: 2009-06-22T02:36:06Z + +[Term] +id: GO:0060754 +name: positive regulation of mast cell chemotaxis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:0060753 ! regulation of mast cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002551 ! mast cell chemotaxis +relationship: positively_regulates GO:0002551 ! mast cell chemotaxis +created_by: dph +creation_date: 2009-06-22T02:38:19Z + +[Term] +id: GO:0060755 +name: negative regulation of mast cell chemotaxis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus." [GOC:dph, GOC:tb] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:0060753 ! regulation of mast cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002551 ! mast cell chemotaxis +relationship: negatively_regulates GO:0002551 ! mast cell chemotaxis +created_by: dph +creation_date: 2009-06-22T02:40:58Z + +[Term] +id: GO:0060756 +name: foraging behavior +namespace: biological_process +def: "Behavior by which an organism locates food." [GOC:dph, GOC:tb] +is_a: GO:0007610 ! behavior +created_by: dph +creation_date: 2009-06-22T02:46:25Z + +[Term] +id: GO:0060757 +name: adult foraging behavior +namespace: biological_process +def: "Behavior by which an adult locates food." [GOC:dph, GOC:tb] +is_a: GO:0060756 ! foraging behavior +created_by: dph +creation_date: 2009-06-22T02:50:56Z + +[Term] +id: GO:0060758 +name: foraging behavior by probing substrate +namespace: biological_process +def: "Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food." [GOC:dph, GOC:tb] +is_a: GO:0060756 ! foraging behavior +created_by: dph +creation_date: 2009-06-22T02:53:09Z + +[Term] +id: GO:0060759 +name: regulation of response to cytokine stimulus +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034097 ! response to cytokine +relationship: regulates GO:0034097 ! response to cytokine +created_by: dph +creation_date: 2009-06-22T02:56:12Z + +[Term] +id: GO:0060760 +name: positive regulation of response to cytokine stimulus +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0060759 ! regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034097 ! response to cytokine +relationship: positively_regulates GO:0034097 ! response to cytokine +created_by: dph +creation_date: 2009-06-22T02:58:04Z + +[Term] +id: GO:0060761 +name: negative regulation of response to cytokine stimulus +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0060759 ! regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034097 ! response to cytokine +relationship: negatively_regulates GO:0034097 ! response to cytokine +created_by: dph +creation_date: 2009-06-22T02:59:57Z + +[Term] +id: GO:0060762 +name: regulation of branching involved in mammary gland duct morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis." [GOC:dph] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060444 ! branching involved in mammary gland duct morphogenesis +relationship: regulates GO:0060444 ! branching involved in mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-06-22T05:20:33Z + +[Term] +id: GO:0060763 +name: mammary duct terminal end bud growth +namespace: biological_process +def: "The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty." [GOC:dph, PMID:10804170] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0060603 ! mammary gland duct morphogenesis +created_by: dph +creation_date: 2009-07-06T07:33:50Z + +[Term] +id: GO:0060764 +name: cell-cell signaling involved in mammary gland development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure." [GOC:dph] +synonym: "cell-cell signalling involved in mammary gland development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0030879 ! mammary gland development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2009-07-06T09:24:53Z + +[Term] +id: GO:0060765 +name: regulation of androgen receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway." [GOC:dph] +synonym: "regulation of androgen receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030521 ! androgen receptor signaling pathway +relationship: regulates GO:0030521 ! androgen receptor signaling pathway +created_by: dph +creation_date: 2009-07-06T11:07:38Z + +[Term] +id: GO:0060766 +name: negative regulation of androgen receptor signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway." [GOC:dph] +synonym: "negative regulation of androgen receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0033144 ! negative regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:0060765 ! regulation of androgen receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030521 ! androgen receptor signaling pathway +relationship: negatively_regulates GO:0030521 ! androgen receptor signaling pathway +created_by: dph +creation_date: 2009-07-06T11:09:36Z + +[Term] +id: GO:0060767 +name: epithelial cell proliferation involved in prostate gland development +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time." [GOC:dph] +is_a: GO:0022414 ! reproductive process +is_a: GO:0050673 ! epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-07-08T07:32:34Z + +[Term] +id: GO:0060768 +name: regulation of epithelial cell proliferation involved in prostate gland development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +relationship: regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +created_by: dph +creation_date: 2009-07-08T07:34:56Z + +[Term] +id: GO:0060769 +name: positive regulation of epithelial cell proliferation involved in prostate gland development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0060768 ! regulation of epithelial cell proliferation involved in prostate gland development +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +relationship: positively_regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +created_by: dph +creation_date: 2009-07-08T07:38:02Z + +[Term] +id: GO:0060770 +name: negative regulation of epithelial cell proliferation involved in prostate gland development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time." [GOC:dph] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060768 ! regulation of epithelial cell proliferation involved in prostate gland development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +relationship: negatively_regulates GO:0060767 ! epithelial cell proliferation involved in prostate gland development +created_by: dph +creation_date: 2009-07-08T07:40:27Z + +[Term] +id: GO:0060771 +name: phyllotactic patterning +namespace: biological_process +def: "The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009956 ! radial pattern formation +created_by: dph +creation_date: 2009-07-25T06:20:33Z + +[Term] +id: GO:0060772 +name: leaf phyllotactic patterning +namespace: biological_process +def: "The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060771 ! phyllotactic patterning +created_by: dph +creation_date: 2009-07-25T06:27:15Z + +[Term] +id: GO:0060773 +name: flower phyllotactic patterning +namespace: biological_process +def: "The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060771 ! phyllotactic patterning +created_by: dph +creation_date: 2009-07-25T06:28:38Z + +[Term] +id: GO:0060774 +name: auxin mediated signaling pathway involved in phyllotactic patterning +namespace: biological_process +def: "The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "auxin mediated signalling pathway involved in phyllotactic patterning" EXACT [GOC:mah] +is_a: GO:0009734 ! auxin-activated signaling pathway +intersection_of: GO:0009734 ! auxin-activated signaling pathway +intersection_of: part_of GO:0060771 ! phyllotactic patterning +relationship: part_of GO:0060771 ! phyllotactic patterning +created_by: dph +creation_date: 2009-07-25T06:31:13Z + +[Term] +id: GO:0060775 +name: planar cell polarity pathway involved in gastrula mediolateral intercalation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +relationship: part_of GO:0060031 ! mediolateral intercalation +created_by: dph +creation_date: 2009-07-25T06:52:50Z + +[Term] +id: GO:0060776 +name: simple leaf morphogenesis +namespace: biological_process +def: "The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009965 ! leaf morphogenesis +created_by: dph +creation_date: 2009-07-25T07:08:44Z + +[Term] +id: GO:0060777 +name: compound leaf morphogenesis +namespace: biological_process +def: "The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009965 ! leaf morphogenesis +created_by: dph +creation_date: 2009-07-25T07:12:30Z + +[Term] +id: GO:0060778 +name: primary leaflet morphogenesis +namespace: biological_process +def: "The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060794 ! leaflet morphogenesis +created_by: dph +creation_date: 2009-07-25T07:15:48Z + +[Term] +id: GO:0060779 +name: secondary leaflet morphogenesis +namespace: biological_process +def: "The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060794 ! leaflet morphogenesis +created_by: dph +creation_date: 2009-07-25T07:19:02Z + +[Term] +id: GO:0060780 +name: intercalary leaflet morphogenesis +namespace: biological_process +def: "The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060794 ! leaflet morphogenesis +created_by: dph +creation_date: 2009-07-25T07:20:46Z + +[Term] +id: GO:0060781 +name: mesenchymal cell proliferation involved in prostate gland development +namespace: biological_process +def: "The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time." [GOC:dph, PMID:12221011] +is_a: GO:0010463 ! mesenchymal cell proliferation +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0010463 ! mesenchymal cell proliferation +intersection_of: part_of GO:0030850 ! prostate gland development +relationship: part_of GO:0030850 ! prostate gland development +created_by: dph +creation_date: 2009-07-28T11:50:56Z + +[Term] +id: GO:0060782 +name: regulation of mesenchymal cell proliferation involved in prostate gland development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, PMID:12221011] +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060781 ! mesenchymal cell proliferation involved in prostate gland development +relationship: regulates GO:0060781 ! mesenchymal cell proliferation involved in prostate gland development +created_by: dph +creation_date: 2009-07-28T11:54:20Z + +[Term] +id: GO:0060783 +name: mesenchymal smoothened signaling pathway involved in prostate gland development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development." [PMID:12221011] +synonym: "mesenchymal hedgehog signaling pathway involved in prostate gland development" EXACT [GOC:bf, GOC:ecd] +synonym: "mesenchymal hh signaling pathway involved in prostate gland development" EXACT [GOC:bf, GOC:ecd] +synonym: "mesenchymal smoothened signalling pathway involved in prostate gland development" EXACT [GOC:mah] +is_a: GO:0007224 ! smoothened signaling pathway +is_a: GO:0022414 ! reproductive process +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +relationship: part_of GO:0060738 ! epithelial-mesenchymal signaling involved in prostate gland development +created_by: dph +creation_date: 2009-07-28T11:57:59Z + +[Term] +id: GO:0060784 +name: regulation of cell proliferation involved in tissue homeostasis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue." [GOC:dph] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0042127 ! regulation of cell population proliferation +intersection_of: part_of GO:0001894 ! tissue homeostasis +relationship: part_of GO:0048873 ! homeostasis of number of cells within a tissue +created_by: dph +creation_date: 2009-07-31T01:46:28Z + +[Term] +id: GO:0060785 +name: regulation of apoptosis involved in tissue homeostasis +namespace: biological_process +def: "Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue." [GOC:dph] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0042981 ! regulation of apoptotic process +intersection_of: part_of GO:0001894 ! tissue homeostasis +relationship: part_of GO:0048873 ! homeostasis of number of cells within a tissue +created_by: dph +creation_date: 2009-07-31T01:49:54Z + +[Term] +id: GO:0060786 +name: regulation of cell differentiation involved in tissue homeostasis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue." [GOC:dph] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0045595 ! regulation of cell differentiation +intersection_of: part_of GO:0001894 ! tissue homeostasis +relationship: part_of GO:0048873 ! homeostasis of number of cells within a tissue +created_by: dph +creation_date: 2009-07-31T01:55:19Z + +[Term] +id: GO:0060787 +name: positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "positive regulation of posterior neural plate formation by FGF receptor signaling pathway" RELATED [GOC:dph, GOC:tb] +synonym: "positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +relationship: positively_regulates GO:0090018 ! posterior neural plate formation +created_by: dph +creation_date: 2009-08-04T09:48:31Z + +[Term] +id: GO:0060788 +name: ectodermal placode formation +namespace: biological_process +def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0071697 ! ectodermal placode morphogenesis +created_by: dph +creation_date: 2009-08-04T12:15:57Z + +[Term] +id: GO:0060789 +name: hair follicle placode formation +namespace: biological_process +def: "The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0001942 ! hair follicle development +created_by: dph +creation_date: 2009-08-04T12:18:26Z + +[Term] +id: GO:0060790 +name: tooth placode formation +namespace: biological_process +def: "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0042475 ! odontogenesis of dentin-containing tooth +created_by: dph +creation_date: 2009-08-04T12:21:47Z + +[Term] +id: GO:0060791 +name: sebaceous gland placode formation +namespace: biological_process +def: "The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0048733 ! sebaceous gland development +created_by: dph +creation_date: 2009-08-04T12:23:09Z + +[Term] +id: GO:0060792 +name: sweat gland development +namespace: biological_process +def: "The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048732 ! gland development +created_by: dph +creation_date: 2009-08-04T12:35:12Z + +[Term] +id: GO:0060793 +name: sweat gland placode formation +namespace: biological_process +def: "The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060788 ! ectodermal placode formation +relationship: part_of GO:0060792 ! sweat gland development +created_by: dph +creation_date: 2009-08-04T12:38:10Z + +[Term] +id: GO:0060794 +name: leaflet morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the leaflet are generated and organized." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060777 ! compound leaf morphogenesis +created_by: dph +creation_date: 2009-08-04T02:58:14Z + +[Term] +id: GO:0060795 +name: cell fate commitment involved in formation of primary germ layer +namespace: biological_process +def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0045165 ! cell fate commitment +intersection_of: GO:0045165 ! cell fate commitment +intersection_of: part_of GO:0001704 ! formation of primary germ layer +relationship: part_of GO:0001704 ! formation of primary germ layer +created_by: dph +creation_date: 2009-08-04T03:11:22Z + +[Term] +id: GO:0060796 +name: regulation of transcription involved in primary germ layer cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0060795 ! cell fate commitment involved in formation of primary germ layer +relationship: part_of GO:0060795 ! cell fate commitment involved in formation of primary germ layer +created_by: dph +creation_date: 2009-08-04T03:40:21Z + +[Term] +id: GO:0060797 +name: transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment" EXACT [GOC:mah] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +relationship: part_of GO:0060795 ! cell fate commitment involved in formation of primary germ layer +created_by: dph +creation_date: 2009-08-04T03:41:44Z + +[Term] +id: GO:0060798 +name: transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification" EXACT [GOC:mah] +is_a: GO:0060797 ! transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0007501 ! mesodermal cell fate specification +created_by: dph +creation_date: 2009-08-06T11:16:11Z + +[Term] +id: GO:0060799 +name: transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification" EXACT [GOC:mah] +is_a: GO:0060797 ! transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0001714 ! endodermal cell fate specification +relationship: part_of GO:0001714 ! endodermal cell fate specification +created_by: dph +creation_date: 2009-08-06T11:24:01Z + +[Term] +id: GO:0060800 +name: regulation of cell differentiation involved in embryonic placenta development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development +relationship: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-08-06T01:20:25Z + +[Term] +id: GO:0060801 +name: negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway +namespace: biological_process +def: "The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway" EXACT [GOC:mah] +is_a: GO:0060806 ! negative regulation of cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-08-06T01:24:24Z + +[Term] +id: GO:0060802 +name: epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +relationship: part_of GO:0009948 ! anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-06T01:36:13Z + +[Term] +id: GO:0060803 +name: BMP signaling pathway involved in mesodermal cell fate specification +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "BMP signalling pathway involved in mesodermal cell fate specification" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0007501 ! mesodermal cell fate specification +relationship: part_of GO:0007501 ! mesodermal cell fate specification +created_by: dph +creation_date: 2009-08-06T01:47:39Z + +[Term] +id: GO:0060804 +name: positive regulation of Wnt signaling pathway by BMP signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "positive regulation of WNT receptor signaling pathway by BMP signaling pathway" EXACT [GOC:bf] +synonym: "positive regulation of Wnt receptor signaling pathway by BMP signaling pathway" EXACT [] +synonym: "positive regulation of WNT receptor signalling pathway by BMP signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of Wnt-activated signaling pathway by BMP signaling pathway" EXACT [GOC:signaling] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: positively_regulates GO:0016055 ! Wnt signaling pathway +created_by: dph +creation_date: 2009-08-06T01:52:48Z + +[Term] +id: GO:0060805 +name: negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060806 ! negative regulation of cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-08-06T01:58:25Z + +[Term] +id: GO:0060806 +name: negative regulation of cell differentiation involved in embryonic placenta development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development +relationship: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development +created_by: dph +creation_date: 2009-08-06T02:02:18Z + +[Term] +id: GO:0060807 +name: regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060796 ! regulation of transcription involved in primary germ layer cell fate commitment +relationship: part_of GO:0001714 ! endodermal cell fate specification +created_by: dph +creation_date: 2009-08-06T02:14:09Z + +[Term] +id: GO:0060808 +name: positive regulation of mesodermal to mesenchymal transition involved in gastrulation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060809 ! mesodermal to mesenchymal transition involved in gastrulation +relationship: positively_regulates GO:0060809 ! mesodermal to mesenchymal transition involved in gastrulation +created_by: dph +creation_date: 2009-08-06T02:32:53Z + +[Term] +id: GO:0060809 +name: mesodermal to mesenchymal transition involved in gastrulation +namespace: biological_process +def: "The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001837 ! epithelial to mesenchymal transition +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0007369 ! gastrulation +created_by: dph +creation_date: 2009-08-06T02:42:09Z + +[Term] +id: GO:0060810 +name: intracellular mRNA localization involved in pattern specification process +namespace: biological_process +def: "Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "intracellular mRNA localisation involved in pattern specification process" EXACT [GOC:mah] +is_a: GO:0008298 ! intracellular mRNA localization +intersection_of: GO:0008298 ! intracellular mRNA localization +intersection_of: part_of GO:0007389 ! pattern specification process +relationship: part_of GO:0007389 ! pattern specification process +created_by: dph +creation_date: 2009-08-07T09:19:58Z + +[Term] +id: GO:0060811 +name: intracellular mRNA localization involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "intracellular mRNA localisation involved in anterior/posterior axis specification" EXACT [GOC:mah] +is_a: GO:0060810 ! intracellular mRNA localization involved in pattern specification process +intersection_of: GO:0008298 ! intracellular mRNA localization +intersection_of: part_of GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0009948 ! anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-07T09:26:22Z + +[Term] +id: GO:0060812 +name: orthodenticle mRNA localization +namespace: biological_process +def: "Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "orthodenticle mRNA localisation" EXACT [GOC:mah] +is_a: GO:0060811 ! intracellular mRNA localization involved in anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-07T09:39:01Z + +[Term] +id: GO:0060813 +name: anterior mRNA localization involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "anterior mRNA localisation involved in anterior/posterior axis specification" EXACT [GOC:mah] +is_a: GO:0060811 ! intracellular mRNA localization involved in anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-07T09:51:47Z + +[Term] +id: GO:0060814 +name: posterior mRNA localization involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "posterior mRNA localisation involved in anterior/posterior axis specification" EXACT [GOC:mah] +is_a: GO:0060811 ! intracellular mRNA localization involved in anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-07T09:54:54Z + +[Term] +id: GO:0060815 +name: regulation of translation involved in anterior/posterior axis specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0006417 ! regulation of translation +intersection_of: part_of GO:0009948 ! anterior/posterior axis specification +relationship: part_of GO:0009948 ! anterior/posterior axis specification +created_by: dph +creation_date: 2009-08-07T10:02:31Z + +[Term] +id: GO:0060816 +name: random inactivation of X chromosome +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: dph +creation_date: 2009-08-11T10:47:30Z + +[Term] +id: GO:0060817 +name: inactivation of paternal X chromosome +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: dph +creation_date: 2009-08-11T10:50:20Z + +[Term] +id: GO:0060818 +name: inactivation of paternal X chromosome by genetic imprinting +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060817 ! inactivation of paternal X chromosome +is_a: GO:0060819 ! inactivation of X chromosome by genetic imprinting +created_by: dph +creation_date: 2009-08-11T10:52:31Z + +[Term] +id: GO:0060819 +name: inactivation of X chromosome by genetic imprinting +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0006349 ! regulation of gene expression by genetic imprinting +is_a: GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: dph +creation_date: 2009-08-11T10:56:06Z + +[Term] +id: GO:0060820 +name: inactivation of X chromosome by heterochromatin assembly +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "inactivation of X chromosome by heterochromatin formation" EXACT [] +is_a: GO:0009048 ! dosage compensation by inactivation of X chromosome +is_a: GO:0031507 ! heterochromatin assembly +created_by: dph +creation_date: 2009-08-11T10:58:06Z + +[Term] +id: GO:0060821 +name: inactivation of X chromosome by DNA methylation +namespace: biological_process +def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: dph +creation_date: 2009-08-11T11:02:19Z + +[Term] +id: GO:0060822 +name: transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification" EXACT [GOC:mah] +is_a: GO:0060798 ! transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0048327 ! axial mesodermal cell fate specification +relationship: part_of GO:0048327 ! axial mesodermal cell fate specification +created_by: dph +creation_date: 2009-08-11T12:55:33Z + +[Term] +id: GO:0060823 +name: canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:signaling] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mtg_signal] +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0021999 ! neural plate anterior/posterior regionalization +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization +created_by: dph +creation_date: 2009-08-11T01:22:42Z + +[Term] +id: GO:0060824 +name: retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0021999 ! neural plate anterior/posterior regionalization +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization +created_by: dph +creation_date: 2009-08-11T01:30:57Z + +[Term] +id: GO:0060825 +name: fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0021999 ! neural plate anterior/posterior regionalization +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization +created_by: dph +creation_date: 2009-08-11T01:40:03Z + +[Term] +id: GO:0060826 +name: transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0021999 ! neural plate anterior/posterior regionalization +relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization +created_by: dph +creation_date: 2009-08-11T01:43:29Z + +[Term] +id: GO:0060827 +name: regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation" EXACT [] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:signaling] +synonym: "regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mtg_signal] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060823 ! canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +relationship: regulates GO:0060823 ! canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +created_by: dph +creation_date: 2009-08-11T01:48:52Z + +[Term] +id: GO:0060828 +name: regulation of canonical Wnt signaling pathway +namespace: biological_process +alt_id: GO:0035411 +alt_id: GO:0035412 +def: "Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "catenin import into nucleus" NARROW [] +synonym: "regulation of canonical Wnt receptor signaling pathway" EXACT [] +synonym: "regulation of canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "regulation of catenin import into nucleus" NARROW [] +synonym: "regulation of catenin protein nuclear translocation" NARROW [GOC:mah] +synonym: "regulation of Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:mtg_signal] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060070 ! canonical Wnt signaling pathway +relationship: regulates GO:0060070 ! canonical Wnt signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13686 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15268 xsd:anyURI +created_by: dph +creation_date: 2009-08-11T01:54:47Z + +[Term] +id: GO:0060829 +name: negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern" EXACT [] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern" EXACT [GOC:signaling] +synonym: "negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation" EXACT [GOC:mtg_signal] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0060827 ! regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060823 ! canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +relationship: negatively_regulates GO:0060823 ! canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +created_by: dph +creation_date: 2009-08-11T01:58:33Z + +[Term] +id: GO:0060830 +name: ciliary receptor clustering involved in smoothened signaling pathway +namespace: biological_process +def: "Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway." [GOC:cilia, GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "ciliary receptor clustering involved in hedgehog signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "ciliary receptor clustering involved in hh signaling pathway" EXACT [GOC:bf, GOC:ecd] +synonym: "ciliary receptor clustering involved in smoothened signalling pathway" EXACT [GOC:mah] +is_a: GO:0043113 ! receptor clustering +relationship: occurs_in GO:0005929 ! cilium +relationship: part_of GO:0007224 ! smoothened signaling pathway +created_by: dph +creation_date: 2009-08-11T02:06:33Z + +[Term] +id: GO:0060831 +name: smoothened signaling pathway involved in dorsal/ventral neural tube patterning +namespace: biological_process +def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:bf, GOC:ecd] +synonym: "smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:mah] +is_a: GO:0007224 ! smoothened signaling pathway +intersection_of: GO:0007224 ! smoothened signaling pathway +intersection_of: part_of GO:0021904 ! dorsal/ventral neural tube patterning +relationship: part_of GO:0021904 ! dorsal/ventral neural tube patterning +created_by: dph +creation_date: 2009-08-11T02:12:58Z + +[Term] +id: GO:0060832 +name: oocyte animal/vegetal axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0007309 ! oocyte axis specification +created_by: dph +creation_date: 2009-08-11T03:11:06Z + +[Term] +id: GO:0060833 +name: Wnt signaling pathway involved in animal/vegetal axis specification +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "Wnt receptor signaling pathway involved in animal/vegetal axis specification" EXACT [] +synonym: "Wnt receptor signalling pathway involved in animal/vegetal axis specification" EXACT [GOC:mah] +synonym: "Wnt- activated signaling pathway involved in animal/vegetal axis specification" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0060832 ! oocyte animal/vegetal axis specification +created_by: dph +creation_date: 2009-08-11T03:20:39Z + +[Term] +id: GO:0060834 +name: oral/aboral axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "oral/aboral axis determination" RELATED [GOC:dph] +is_a: GO:0000578 ! embryonic axis specification +created_by: dph +creation_date: 2009-08-11T03:25:26Z + +[Term] +id: GO:0060835 +name: transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification" EXACT [GOC:mah] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0060834 ! oral/aboral axis specification +relationship: part_of GO:0060834 ! oral/aboral axis specification +created_by: dph +creation_date: 2009-08-11T03:30:40Z + +[Term] +id: GO:0060836 +name: lymphatic endothelial cell differentiation +namespace: biological_process +def: "The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0045446 ! endothelial cell differentiation +relationship: part_of GO:0001945 ! lymph vessel development +created_by: dph +creation_date: 2009-08-11T03:45:20Z + +[Term] +id: GO:0060837 +name: blood vessel endothelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0045446 ! endothelial cell differentiation +relationship: part_of GO:0001568 ! blood vessel development +created_by: dph +creation_date: 2009-08-11T03:47:36Z + +[Term] +id: GO:0060838 +name: lymphatic endothelial cell fate commitment +namespace: biological_process +def: "The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060839 ! endothelial cell fate commitment +relationship: part_of GO:0060836 ! lymphatic endothelial cell differentiation +created_by: dph +creation_date: 2009-08-11T03:51:45Z + +[Term] +id: GO:0060839 +name: endothelial cell fate commitment +namespace: biological_process +def: "The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0072148 ! epithelial cell fate commitment +relationship: part_of GO:0045446 ! endothelial cell differentiation +created_by: dph +creation_date: 2009-08-11T03:52:53Z + +[Term] +id: GO:0060840 +name: artery development +namespace: biological_process +def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001568 ! blood vessel development +created_by: dph +creation_date: 2009-08-12T10:10:51Z + +[Term] +id: GO:0060841 +name: venous blood vessel development +namespace: biological_process +def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001568 ! blood vessel development +created_by: dph +creation_date: 2009-08-12T10:14:07Z + +[Term] +id: GO:0060842 +name: arterial endothelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060837 ! blood vessel endothelial cell differentiation +created_by: dph +creation_date: 2009-08-12T10:41:34Z + +[Term] +id: GO:0060843 +name: venous endothelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060837 ! blood vessel endothelial cell differentiation +created_by: dph +creation_date: 2009-08-12T10:43:40Z + +[Term] +id: GO:0060844 +name: arterial endothelial cell fate commitment +namespace: biological_process +def: "The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060846 ! blood vessel endothelial cell fate commitment +relationship: part_of GO:0060842 ! arterial endothelial cell differentiation +created_by: dph +creation_date: 2009-08-12T10:49:00Z + +[Term] +id: GO:0060845 +name: venous endothelial cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060846 ! blood vessel endothelial cell fate commitment +relationship: part_of GO:0060843 ! venous endothelial cell differentiation +created_by: dph +creation_date: 2009-08-12T10:51:23Z + +[Term] +id: GO:0060846 +name: blood vessel endothelial cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060839 ! endothelial cell fate commitment +relationship: part_of GO:0060837 ! blood vessel endothelial cell differentiation +created_by: dph +creation_date: 2009-08-12T10:56:14Z + +[Term] +id: GO:0060847 +name: endothelial cell fate specification +namespace: biological_process +def: "The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0060839 ! endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:00:04Z + +[Term] +id: GO:0060848 +name: endothelial cell fate determination +namespace: biological_process +def: "A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0060839 ! endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:11:14Z + +[Term] +id: GO:0060849 +name: regulation of transcription involved in lymphatic endothelial cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0060838 ! lymphatic endothelial cell fate commitment +relationship: part_of GO:0060838 ! lymphatic endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:19:14Z + +[Term] +id: GO:0060850 +name: regulation of transcription involved in cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0045165 ! cell fate commitment +relationship: part_of GO:0045165 ! cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:40:09Z + +[Term] +id: GO:0060851 +name: vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment +namespace: biological_process +def: "The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment" EXACT [GOC:mah] +is_a: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +intersection_of: GO:0048010 ! vascular endothelial growth factor receptor signaling pathway +intersection_of: part_of GO:0060838 ! lymphatic endothelial cell fate commitment +relationship: part_of GO:0060838 ! lymphatic endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:45:19Z + +[Term] +id: GO:0060852 +name: regulation of transcription involved in venous endothelial cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0060845 ! venous endothelial cell fate commitment +relationship: part_of GO:0060845 ! venous endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:49:49Z + +[Term] +id: GO:0060853 +name: Notch signaling pathway involved in arterial endothelial cell fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "Notch signalling pathway involved in arterial endothelial cell fate commitment" EXACT [GOC:mah] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0060844 ! arterial endothelial cell fate commitment +relationship: part_of GO:0060844 ! arterial endothelial cell fate commitment +created_by: dph +creation_date: 2009-08-12T11:54:49Z + +[Term] +id: GO:0060854 +name: branching involved in lymph vessel morphogenesis +namespace: biological_process +def: "The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "patterning of lymph vessels" BROAD [GOC:dph] +is_a: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube +intersection_of: part_of GO:0036303 ! lymph vessel morphogenesis +relationship: part_of GO:0001946 ! lymphangiogenesis +created_by: dph +creation_date: 2009-08-12T12:00:48Z + +[Term] +id: GO:0060855 +name: venous endothelial cell migration involved in lymph vessel development +namespace: biological_process +def: "The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0043534 ! blood vessel endothelial cell migration +relationship: part_of GO:0001945 ! lymph vessel development +created_by: dph +creation_date: 2009-08-12T12:07:27Z + +[Term] +id: GO:0060856 +name: establishment of blood-brain barrier +namespace: biological_process +def: "Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:aruk, GOC:dph, GOC:sart, PMID:20080302, PMID:30280653] +synonym: "establishment of BBB" EXACT [] +synonym: "establishment of blood/brain barrier" EXACT [] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0007417 ! central nervous system development +created_by: dph +creation_date: 2009-08-12T12:12:59Z + +[Term] +id: GO:0060857 +name: establishment of glial blood-brain barrier +namespace: biological_process +def: "Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier." [GOC:dph, GOC:sart, PMID:20080302] +synonym: "establishment of glial BBB" EXACT [] +synonym: "establishment of glial blood/brain barrier" EXACT [] +is_a: GO:0021782 ! glial cell development +is_a: GO:0060856 ! establishment of blood-brain barrier +created_by: dph +creation_date: 2009-08-12T12:17:51Z + +[Term] +id: GO:0060858 +name: vesicle-mediated transport involved in floral organ abscission +namespace: biological_process +def: "The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "membrane trafficking involved in floral organ shedding" RELATED [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0016192 ! vesicle-mediated transport +intersection_of: part_of GO:0010227 ! floral organ abscission +relationship: part_of GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T03:48:54Z + +[Term] +id: GO:0060859 +name: regulation of vesicle-mediated transport involved in floral organ abscission +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:0060860 ! regulation of floral organ abscission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060858 ! vesicle-mediated transport involved in floral organ abscission +relationship: regulates GO:0060858 ! vesicle-mediated transport involved in floral organ abscission +created_by: dph +creation_date: 2009-08-12T03:56:21Z + +[Term] +id: GO:0060860 +name: regulation of floral organ abscission +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009909 ! regulation of flower development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010227 ! floral organ abscission +relationship: regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T03:59:45Z + +[Term] +id: GO:0060861 +name: positive regulation of floral organ abscission +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009911 ! positive regulation of flower development +is_a: GO:0060860 ! regulation of floral organ abscission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010227 ! floral organ abscission +relationship: positively_regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T04:03:09Z + +[Term] +id: GO:0060862 +name: negative regulation of floral organ abscission +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009910 ! negative regulation of flower development +is_a: GO:0060860 ! regulation of floral organ abscission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010227 ! floral organ abscission +relationship: negatively_regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T04:05:23Z + +[Term] +id: GO:0060863 +name: regulation of floral organ abscission by signal transduction +namespace: biological_process +def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0007165 ! signal transduction +is_a: GO:0060860 ! regulation of floral organ abscission +intersection_of: GO:0007165 ! signal transduction +intersection_of: regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T04:07:41Z + +[Term] +id: GO:0060864 +name: positive regulation of floral organ abscission by small GTPase mediated signal transduction +namespace: biological_process +def: "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0007264 ! small GTPase mediated signal transduction +is_a: GO:0060861 ! positive regulation of floral organ abscission +is_a: GO:0060863 ! regulation of floral organ abscission by signal transduction +intersection_of: GO:0007264 ! small GTPase mediated signal transduction +intersection_of: positively_regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T04:34:56Z + +[Term] +id: GO:0060865 +name: negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:0060862 ! negative regulation of floral organ abscission +is_a: GO:0060863 ! regulation of floral organ abscission by signal transduction +intersection_of: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: negatively_regulates GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T04:42:14Z + +[Term] +id: GO:0060866 +name: leaf abscission +namespace: biological_process +def: "The controlled shedding of a leaf." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009838 ! abscission +created_by: dph +creation_date: 2009-08-12T06:33:55Z + +[Term] +id: GO:0060867 +name: fruit abscission +namespace: biological_process +def: "The controlled shedding of a fruit." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009838 ! abscission +created_by: dph +creation_date: 2009-08-12T06:35:28Z + +[Term] +id: GO:0060868 +name: regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction +namespace: biological_process +def: "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0007264 ! small GTPase mediated signal transduction +is_a: GO:0060859 ! regulation of vesicle-mediated transport involved in floral organ abscission +is_a: GO:0060863 ! regulation of floral organ abscission by signal transduction +intersection_of: GO:0007264 ! small GTPase mediated signal transduction +intersection_of: regulates GO:0060858 ! vesicle-mediated transport involved in floral organ abscission +created_by: dph +creation_date: 2009-08-12T06:52:13Z + +[Term] +id: GO:0060869 +name: transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:signaling, GOC:tb] +synonym: "transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission" EXACT [GOC:mah] +is_a: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: part_of GO:0010227 ! floral organ abscission +relationship: part_of GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T07:02:07Z + +[Term] +id: GO:0060870 +name: cell wall disassembly involved in floral organ abscission +namespace: biological_process +def: "A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009830 ! cell wall modification involved in abscission +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0044277 ! cell wall disassembly +intersection_of: part_of GO:0010227 ! floral organ abscission +relationship: part_of GO:0010227 ! floral organ abscission +created_by: dph +creation_date: 2009-08-12T07:15:36Z + +[Term] +id: GO:0060872 +name: semicircular canal development +namespace: biological_process +def: "The progression of the semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0048839 ! inner ear development +created_by: dph +creation_date: 2009-08-13T09:36:37Z + +[Term] +id: GO:0060873 +name: anterior semicircular canal development +namespace: biological_process +def: "The progession of the anterior semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060872 ! semicircular canal development +created_by: dph +creation_date: 2009-08-13T09:39:49Z + +[Term] +id: GO:0060874 +name: posterior semicircular canal development +namespace: biological_process +def: "The progession of the posterior semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060872 ! semicircular canal development +created_by: dph +creation_date: 2009-08-13T09:42:39Z + +[Term] +id: GO:0060875 +name: lateral semicircular canal development +namespace: biological_process +def: "The progession of the lateral semicircular canal from its initial formation to the mature structure." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060872 ! semicircular canal development +created_by: dph +creation_date: 2009-08-13T09:43:25Z + +[Term] +id: GO:0060876 +name: semicircular canal formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0035148 ! tube formation +relationship: part_of GO:0048752 ! semicircular canal morphogenesis +created_by: dph +creation_date: 2009-08-13T09:45:07Z + +[Term] +id: GO:0060877 +name: regionalization involved in semicircular canal formation +namespace: biological_process +def: "The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0003002 ! regionalization +intersection_of: GO:0003002 ! regionalization +intersection_of: part_of GO:0060876 ! semicircular canal formation +relationship: part_of GO:0060876 ! semicircular canal formation +created_by: dph +creation_date: 2009-08-13T09:56:45Z + +[Term] +id: GO:0060878 +name: pouch outgrowth involved in semicircular canal formation +namespace: biological_process +def: "The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0060571 ! morphogenesis of an epithelial fold +intersection_of: GO:0060571 ! morphogenesis of an epithelial fold +intersection_of: part_of GO:0060876 ! semicircular canal formation +relationship: part_of GO:0060876 ! semicircular canal formation +created_by: dph +creation_date: 2009-08-13T10:01:01Z + +[Term] +id: GO:0060879 +name: semicircular canal fusion +namespace: biological_process +def: "Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060606 ! tube closure +relationship: part_of GO:0060876 ! semicircular canal formation +created_by: dph +creation_date: 2009-08-13T10:05:51Z + +[Term] +id: GO:0060880 +name: cell morphogenesis involved in semicircular canal fusion +namespace: biological_process +def: "The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0048598 ! embryonic morphogenesis +intersection_of: GO:0000902 ! cell morphogenesis +intersection_of: part_of GO:0060879 ! semicircular canal fusion +relationship: part_of GO:0060879 ! semicircular canal fusion +created_by: dph +creation_date: 2009-08-13T10:13:25Z + +[Term] +id: GO:0060882 +name: basement membrane disassembly involved in semicircular canal fusion +namespace: biological_process +def: "A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "basal lamina disassembly involved in semicircular canal fusion" RELATED [] +is_a: GO:0034769 ! basement membrane disassembly +intersection_of: GO:0034769 ! basement membrane disassembly +intersection_of: part_of GO:0060879 ! semicircular canal fusion +relationship: part_of GO:0060879 ! semicircular canal fusion +created_by: dph +creation_date: 2009-08-13T11:29:52Z + +[Term] +id: GO:0060883 +name: regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication +namespace: biological_process +def: "Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication" RELATED [] +is_a: GO:0007154 ! cell communication +is_a: GO:0010715 ! regulation of extracellular matrix disassembly +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0110011 ! regulation of basement membrane organization +is_a: GO:2000027 ! regulation of animal organ morphogenesis +relationship: regulates GO:0060882 ! basement membrane disassembly involved in semicircular canal fusion +created_by: dph +creation_date: 2009-08-13T11:31:56Z + +[Term] +id: GO:0060884 +name: clearance of cells from fusion plate +namespace: biological_process +def: "The morphogenetic process in which cells are removed from the inner loop of a semicircular canal." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0002009 ! morphogenesis of an epithelium +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0048752 ! semicircular canal morphogenesis +created_by: dph +creation_date: 2009-08-13T12:25:59Z + +[Term] +id: GO:0060885 +name: clearance of cells from fusion plate by apoptotic process +namespace: biological_process +def: "Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals." [GOC:dph, GOC:mtg_apoptosis, GOC:sdb_2009, GOC:tb] +synonym: "clearance of cells from fusion plate by apoptosis" NARROW [] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +is_a: GO:0060884 ! clearance of cells from fusion plate +created_by: dph +creation_date: 2009-08-13T12:30:17Z + +[Term] +id: GO:0060886 +name: clearance of cells from fusion plate by epithelial to mesenchymal transition +namespace: biological_process +def: "The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0001837 ! epithelial to mesenchymal transition +is_a: GO:0060884 ! clearance of cells from fusion plate +created_by: dph +creation_date: 2009-08-13T12:34:19Z + +[Term] +id: GO:0060887 +name: limb epidermis development +namespace: biological_process +def: "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0098773 ! skin epidermis development +relationship: part_of GO:0060173 ! limb development +created_by: dph +creation_date: 2009-08-13T12:39:39Z + +[Term] +id: GO:0060888 +name: limb epidermis stratification +namespace: biological_process +def: "The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0003002 ! regionalization +is_a: GO:0060887 ! limb epidermis development +created_by: dph +creation_date: 2009-08-13T12:45:48Z + +[Term] +id: GO:0060889 +name: limb basal epidermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009913 ! epidermal cell differentiation +is_a: GO:0048863 ! stem cell differentiation +relationship: part_of GO:0060887 ! limb epidermis development +created_by: dph +creation_date: 2009-08-13T01:22:12Z + +[Term] +id: GO:0060890 +name: limb spinous cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0030216 ! keratinocyte differentiation +relationship: part_of GO:0060887 ! limb epidermis development +created_by: dph +creation_date: 2009-08-13T01:31:30Z + +[Term] +id: GO:0060891 +name: limb granular cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0030216 ! keratinocyte differentiation +relationship: part_of GO:0060887 ! limb epidermis development +created_by: dph +creation_date: 2009-08-13T01:33:14Z + +[Term] +id: GO:0060892 +name: limb basal epidermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009957 ! epidermal cell fate specification +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0060888 ! limb epidermis stratification +relationship: part_of GO:0060889 ! limb basal epidermal cell differentiation +created_by: dph +creation_date: 2009-08-13T01:41:47Z + +[Term] +id: GO:0060893 +name: limb granular cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009957 ! epidermal cell fate specification +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0060888 ! limb epidermis stratification +relationship: part_of GO:0060891 ! limb granular cell differentiation +created_by: dph +creation_date: 2009-08-13T01:44:14Z + +[Term] +id: GO:0060894 +name: limb spinous cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009957 ! epidermal cell fate specification +is_a: GO:0060573 ! cell fate specification involved in pattern specification +relationship: part_of GO:0060888 ! limb epidermis stratification +relationship: part_of GO:0060890 ! limb spinous cell differentiation +created_by: dph +creation_date: 2009-08-13T01:46:23Z + +[Term] +id: GO:0060895 +name: retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0021513 ! spinal cord dorsal/ventral patterning +relationship: part_of GO:0021513 ! spinal cord dorsal/ventral patterning +created_by: dph +creation_date: 2009-08-13T01:51:50Z + +[Term] +id: GO:0060896 +name: neural plate pattern specification +namespace: biological_process +def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0007389 ! pattern specification process +created_by: dph +creation_date: 2009-08-13T02:06:27Z + +[Term] +id: GO:0060897 +name: neural plate regionalization +namespace: biological_process +def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0003002 ! regionalization +is_a: GO:0060896 ! neural plate pattern specification +created_by: dph +creation_date: 2009-08-13T02:09:04Z + +[Term] +id: GO:0060898 +name: eye field cell fate commitment involved in camera-type eye formation +namespace: biological_process +def: "The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0060581 ! cell fate commitment involved in pattern specification +relationship: part_of GO:0046619 ! optic placode formation involved in camera-type eye formation +relationship: part_of GO:0060897 ! neural plate regionalization +created_by: dph +creation_date: 2009-08-13T02:10:58Z + +[Term] +id: GO:0060899 +name: obsolete regulation of transcription involved in eye field cell fate commitment of camera-type eye +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle." [GOC:dph, GOC:sdb_2009, GOC:tb] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2009-08-13T02:11:48Z + +[Term] +id: GO:0060900 +name: embryonic camera-type eye formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis +created_by: dph +creation_date: 2009-08-13T02:26:54Z + +[Term] +id: GO:0060901 +name: regulation of hair cycle by canonical Wnt signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "regulation of hair cycle by canonical Wnt receptor signaling pathway" EXACT [] +synonym: "regulation of hair cycle by canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of hair cycle by canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:mtg_signal] +is_a: GO:0042634 ! regulation of hair cycle +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: regulates GO:0042633 ! hair cycle +created_by: dph +creation_date: 2009-08-13T02:41:10Z + +[Term] +id: GO:0060902 +name: regulation of hair cycle by BMP signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "regulation of hair cycle by BMP signalling pathway" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +is_a: GO:0042634 ! regulation of hair cycle +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: regulates GO:0042633 ! hair cycle +created_by: dph +creation_date: 2009-08-13T02:45:12Z + +[Term] +id: GO:0060903 +name: positive regulation of meiosis I +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [GOC:dph, GOC:tb] +is_a: GO:0045836 ! positive regulation of meiotic nuclear division +is_a: GO:0060631 ! regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007127 ! meiosis I +relationship: positively_regulates GO:0007127 ! meiosis I +created_by: dph +creation_date: 2009-08-14T01:06:57Z + +[Term] +id: GO:0060904 +name: regulation of protein folding in endoplasmic reticulum +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)." [GOC:dph, GOC:tb] +is_a: GO:1903332 ! regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034975 ! protein folding in endoplasmic reticulum +relationship: regulates GO:0034975 ! protein folding in endoplasmic reticulum +created_by: dph +creation_date: 2009-08-14T01:12:00Z + +[Term] +id: GO:0060905 +name: regulation of induction of conjugation upon nitrogen starvation +namespace: biological_process +def: "Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation." [GOC:dph, GOC:tb] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0031137 ! regulation of conjugation with cellular fusion +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031142 ! induction of conjugation upon nitrogen starvation +relationship: regulates GO:0031142 ! induction of conjugation upon nitrogen starvation +created_by: dph +creation_date: 2009-08-14T01:17:50Z + +[Term] +id: GO:0060906 +name: negative regulation of heterochromatin assembly by small RNA +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of heterochromatin assembly by small RNA." [GOC:dph, GOC:tb] +synonym: "negative regulation of chromatin silencing by small RNA" RELATED [] +synonym: "negative regulation of RNAi-mediated heterochromatin assembly" EXACT [] +is_a: GO:0010964 ! regulation of heterochromatin assembly by small RNA +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031048 ! heterochromatin assembly by small RNA +relationship: negatively_regulates GO:0031048 ! heterochromatin assembly by small RNA +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: dph +creation_date: 2009-08-14T01:22:24Z + +[Term] +id: GO:0060907 +name: positive regulation of macrophage cytokine production +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:dph, GOC:tb] +is_a: GO:0010935 ! regulation of macrophage cytokine production +is_a: GO:0061081 ! positive regulation of myeloid leukocyte cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010934 ! macrophage cytokine production +relationship: positively_regulates GO:0010934 ! macrophage cytokine production +created_by: dph +creation_date: 2009-09-04T02:32:18Z + +[Term] +id: GO:0060908 +name: plasmid copy number maintenance +namespace: biological_process +def: "The maintenance of the number of copies of extrachromosomal plasmid DNA." [GOC:dph, GOC:tb] +is_a: GO:0006276 ! plasmid maintenance +created_by: dph +creation_date: 2009-09-04T02:49:08Z + +[Term] +id: GO:0060909 +name: regulation of DNA replication initiation involved in plasmid copy number maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb] +is_a: GO:0030174 ! regulation of DNA-dependent DNA replication initiation +relationship: part_of GO:0060908 ! plasmid copy number maintenance +created_by: dph +creation_date: 2009-09-04T02:51:48Z + +[Term] +id: GO:0060910 +name: negative regulation of DNA replication initiation involved in plasmid copy number maintenance +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance." [GOC:dph, GOC:tb] +is_a: GO:0032297 ! negative regulation of DNA-dependent DNA replication initiation +is_a: GO:0060909 ! regulation of DNA replication initiation involved in plasmid copy number maintenance +created_by: dph +creation_date: 2009-09-04T02:56:29Z + +[Term] +id: GO:0060911 +name: cardiac cell fate commitment +namespace: biological_process +def: "The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system." [GOC:mtg_heart] +synonym: "cardiocyte cell fate commitment" EXACT [GOC:dph] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0035051 ! cardiocyte differentiation +created_by: dph +creation_date: 2009-09-17T08:47:00Z + +[Term] +id: GO:0060912 +name: cardiac cell fate specification +namespace: biological_process +def: "The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:mtg_heart] +synonym: "cardiocyte cell fate specification" EXACT [GOC:dph] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0060911 ! cardiac cell fate commitment +created_by: dph +creation_date: 2009-09-17T08:53:21Z + +[Term] +id: GO:0060913 +name: cardiac cell fate determination +namespace: biological_process +def: "The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:mtg_heart] +synonym: "cardiocyte cell fate determination" RELATED [GOC:dph] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0060911 ! cardiac cell fate commitment +created_by: dph +creation_date: 2009-09-17T08:55:29Z + +[Term] +id: GO:0060914 +name: heart formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart] +synonym: "cardiogenesis" RELATED [GOC:mtg_heart] +is_a: GO:0048645 ! animal organ formation +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2009-09-17T09:02:13Z + +[Term] +id: GO:0060915 +name: mesenchymal cell differentiation involved in lung development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] +is_a: GO:0048762 ! mesenchymal cell differentiation +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0030324 ! lung development +relationship: part_of GO:0030324 ! lung development +created_by: dph +creation_date: 2009-09-18T11:45:33Z + +[Term] +id: GO:0060916 +name: mesenchymal cell proliferation involved in lung development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph] +is_a: GO:0010463 ! mesenchymal cell proliferation +intersection_of: GO:0010463 ! mesenchymal cell proliferation +intersection_of: part_of GO:0030324 ! lung development +relationship: part_of GO:0030324 ! lung development +created_by: dph +creation_date: 2009-09-18T11:50:17Z + +[Term] +id: GO:0060917 +name: regulation of (1->6)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans." [GOC:dph, GOC:tb] +synonym: "regulation of 1,6-beta-glucan biosynthetic process" EXACT [] +is_a: GO:0032951 ! regulation of beta-glucan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006078 ! (1->6)-beta-D-glucan biosynthetic process +relationship: regulates GO:0006078 ! (1->6)-beta-D-glucan biosynthetic process +created_by: dph +creation_date: 2009-09-18T02:15:01Z + +[Term] +id: GO:0060918 +name: auxin transport +namespace: biological_process +def: "The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0009914 ! hormone transport +created_by: dph +creation_date: 2009-09-28T02:44:54Z + +[Term] +id: GO:0060919 +name: auxin influx +namespace: biological_process +def: "The process involved in the transport of auxin into the cell." [GOC:dph, GOC:tb] +is_a: GO:0060918 ! auxin transport +created_by: dph +creation_date: 2009-09-28T02:49:18Z + +[Term] +id: GO:0060920 +name: cardiac pacemaker cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +synonym: "pacemaker cell differentiation" BROAD [] +is_a: GO:0055007 ! cardiac muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T11:01:31Z + +[Term] +id: GO:0060921 +name: sinoatrial node cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] +synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart] +synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "sinus node cell differentiation" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0060920 ! cardiac pacemaker cell differentiation +relationship: part_of GO:0003163 ! sinoatrial node development +created_by: dph +creation_date: 2009-09-29T11:03:30Z + +[Term] +id: GO:0060922 +name: atrioventricular node cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart] +synonym: "AV node cell differentiation" RELATED [GOC:mtg_heart] +is_a: GO:0003292 ! cardiac septum cell differentiation +is_a: GO:0060920 ! cardiac pacemaker cell differentiation +relationship: part_of GO:0003162 ! atrioventricular node development +created_by: dph +creation_date: 2009-09-29T11:07:06Z + +[Term] +id: GO:0060923 +name: cardiac muscle cell fate commitment +namespace: biological_process +def: "The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart] +synonym: "cardiomyocyte cell fate commitment" EXACT [GOC:mtg_heart] +synonym: "heart muscle cell fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0042693 ! muscle cell fate commitment +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0055007 ! cardiac muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T11:13:32Z + +[Term] +id: GO:0060924 +name: atrial cardiac muscle cell fate commitment +namespace: biological_process +def: "The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart] +synonym: "atrial cardiomyocyte cell fate commitment" RELATED [GOC:mtg_heart] +synonym: "atrial heart muscle cell fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0060923 ! cardiac muscle cell fate commitment +relationship: part_of GO:0055011 ! atrial cardiac muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T11:46:10Z + +[Term] +id: GO:0060925 +name: ventricular cardiac muscle cell fate commitment +namespace: biological_process +def: "The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:mtg_heart] +synonym: "ventricular cardiomyocyte cell fate commitment" EXACT [GOC:mtg_heart] +synonym: "ventricular heart muscle cell fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0060923 ! cardiac muscle cell fate commitment +relationship: part_of GO:0055012 ! ventricular cardiac muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T11:49:39Z + +[Term] +id: GO:0060926 +name: cardiac pacemaker cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +synonym: "pacemaker cell development" BROAD [] +is_a: GO:0055013 ! cardiac muscle cell development +relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation +created_by: dph +creation_date: 2009-09-29T11:51:55Z + +[Term] +id: GO:0060927 +name: cardiac pacemaker cell fate commitment +namespace: biological_process +def: "The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] +synonym: "pacemaker cell fate commitment" BROAD [] +is_a: GO:0060923 ! cardiac muscle cell fate commitment +relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation +created_by: dph +creation_date: 2009-09-29T11:54:22Z + +[Term] +id: GO:0060928 +name: atrioventricular node cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart] +synonym: "AV node cell development" EXACT [GOC:mtg_heart] +is_a: GO:0060926 ! cardiac pacemaker cell development +relationship: part_of GO:0060922 ! atrioventricular node cell differentiation +created_by: dph +creation_date: 2009-09-29T11:59:26Z + +[Term] +id: GO:0060929 +name: atrioventricular node cell fate commitment +namespace: biological_process +def: "The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells." [GOC:mtg_heart] +synonym: "AV node cell fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0060927 ! cardiac pacemaker cell fate commitment +relationship: part_of GO:0060922 ! atrioventricular node cell differentiation +created_by: dph +creation_date: 2009-09-29T12:01:24Z + +[Term] +id: GO:0060930 +name: sinoatrial node cell fate commitment +namespace: biological_process +def: "The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] +synonym: "SA node cell commitment" EXACT [GOC:mtg_heart] +synonym: "SAN cell commitment" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "sinus node cell commitment" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0060927 ! cardiac pacemaker cell fate commitment +relationship: part_of GO:0060921 ! sinoatrial node cell differentiation +created_by: dph +creation_date: 2009-09-29T12:03:38Z + +[Term] +id: GO:0060931 +name: sinoatrial node cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] +synonym: "SA node cell development" EXACT [GOC:mtg_heart] +synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "sinus node cell development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0060926 ! cardiac pacemaker cell development +relationship: part_of GO:0060921 ! sinoatrial node cell differentiation +created_by: dph +creation_date: 2009-09-29T12:05:47Z + +[Term] +id: GO:0060932 +name: His-Purkinje system cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] +is_a: GO:0055007 ! cardiac muscle cell differentiation +relationship: part_of GO:0003164 ! His-Purkinje system development +created_by: dph +creation_date: 2009-09-29T01:10:32Z + +[Term] +id: GO:0060933 +name: His-Purkinje system cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation +created_by: dph +creation_date: 2009-09-29T01:15:02Z + +[Term] +id: GO:0060934 +name: His-Purkinje system cell fate commitment +namespace: biological_process +def: "The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation +created_by: dph +creation_date: 2009-09-29T01:17:00Z + +[Term] +id: GO:0060935 +name: cardiac fibroblast cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0035051 ! cardiocyte differentiation +created_by: dph +creation_date: 2009-09-29T01:20:04Z + +[Term] +id: GO:0060936 +name: cardiac fibroblast cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:23:03Z + +[Term] +id: GO:0060937 +name: cardiac fibroblast cell fate commitment +namespace: biological_process +def: "The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:24:59Z + +[Term] +id: GO:0060938 +name: epicardium-derived cardiac fibroblast cell differentiation +namespace: biological_process +def: "The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060935 ! cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:28:03Z + +[Term] +id: GO:0060939 +name: epicardium-derived cardiac fibroblast cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060936 ! cardiac fibroblast cell development +relationship: part_of GO:0060938 ! epicardium-derived cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:29:19Z + +[Term] +id: GO:0060940 +name: epithelial to mesenchymal transition involved in cardiac fibroblast development +namespace: biological_process +def: "A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast." [GOC:mtg_heart] +is_a: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: GO:0060317 ! cardiac epithelial to mesenchymal transition +intersection_of: part_of GO:0060939 ! epicardium-derived cardiac fibroblast cell development +relationship: part_of GO:0060939 ! epicardium-derived cardiac fibroblast cell development +created_by: dph +creation_date: 2009-09-29T01:32:36Z + +[Term] +id: GO:0060941 +name: epicardium-derived cardiac fibroblast cell fate commitment +namespace: biological_process +def: "The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060937 ! cardiac fibroblast cell fate commitment +relationship: part_of GO:0060938 ! epicardium-derived cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:44:36Z + +[Term] +id: GO:0060942 +name: neural crest-derived cardiac fibroblast cell differentiation +namespace: biological_process +def: "The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060935 ! cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T01:54:19Z + +[Term] +id: GO:0060943 +name: neural crest-derived cardiac fibroblast cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060936 ! cardiac fibroblast cell development +relationship: part_of GO:0060942 ! neural crest-derived cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T02:31:24Z + +[Term] +id: GO:0060944 +name: neural crest-derived cardiac fibroblast cell fate commitment +namespace: biological_process +def: "The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] +is_a: GO:0060937 ! cardiac fibroblast cell fate commitment +relationship: part_of GO:0060942 ! neural crest-derived cardiac fibroblast cell differentiation +created_by: dph +creation_date: 2009-09-29T02:42:39Z + +[Term] +id: GO:0060945 +name: cardiac neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart] +synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart] +is_a: GO:0030182 ! neuron differentiation +is_a: GO:0035051 ! cardiocyte differentiation +relationship: part_of GO:0048483 ! autonomic nervous system development +created_by: dph +creation_date: 2009-09-29T02:45:33Z + +[Term] +id: GO:0060946 +name: cardiac blood vessel endothelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart] +is_a: GO:0003348 ! cardiac endothelial cell differentiation +is_a: GO:0060837 ! blood vessel endothelial cell differentiation +created_by: dph +creation_date: 2009-09-29T02:48:55Z + +[Term] +id: GO:0060947 +name: cardiac vascular smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers." [GOC:mtg_heart] +synonym: "heart vascular smooth muscle cell differentiation" EXACT [GOC:mtg_heart] +is_a: GO:0035051 ! cardiocyte differentiation +is_a: GO:0035886 ! vascular smooth muscle cell differentiation +relationship: part_of GO:0060976 ! coronary vasculature development +created_by: dph +creation_date: 2009-09-29T02:56:08Z + +[Term] +id: GO:0060948 +name: cardiac vascular smooth muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state." [GOC:mtg_heart] +synonym: "heart vascular smooth muscle cell development" EXACT [GOC:mtg_heart] +is_a: GO:0055006 ! cardiac cell development +is_a: GO:0097084 ! vascular smooth muscle cell development +relationship: part_of GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T03:00:24Z + +[Term] +id: GO:0060949 +name: cardiac vascular smooth muscle cell fate commitment +namespace: biological_process +def: "The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell." [GOC:mtg_heart] +synonym: "heart vascular smooth muscle cell fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0060911 ! cardiac cell fate commitment +is_a: GO:0097081 ! vascular smooth muscle cell fate commitment +relationship: part_of GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: dph +creation_date: 2009-09-29T03:02:45Z + +[Term] +id: GO:0060950 +name: cardiac glial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] +is_a: GO:0010001 ! glial cell differentiation +is_a: GO:0035051 ! cardiocyte differentiation +created_by: dph +creation_date: 2009-09-29T03:06:37Z + +[Term] +id: GO:0060951 +name: neural crest-derived cardiac glial cell differentiation +namespace: biological_process +def: "The process in which a neural crest cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] +is_a: GO:0060950 ! cardiac glial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:08:06Z + +[Term] +id: GO:0060952 +name: cardiac glial cell development +namespace: biological_process +def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart] +is_a: GO:0021782 ! glial cell development +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0060950 ! cardiac glial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:09:24Z + +[Term] +id: GO:0060953 +name: cardiac glial cell fate commitment +namespace: biological_process +def: "The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells." [GOC:mtg_heart] +is_a: GO:0021781 ! glial cell fate commitment +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0060950 ! cardiac glial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:11:23Z + +[Term] +id: GO:0060954 +name: neural crest-derived cardiac glial cell development +namespace: biological_process +def: "The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:mtg_heart] +is_a: GO:0060952 ! cardiac glial cell development +relationship: part_of GO:0060951 ! neural crest-derived cardiac glial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:14:15Z + +[Term] +id: GO:0060955 +name: neural crest-derived cardiac glial cell fate commitment +namespace: biological_process +def: "The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells." [GOC:mtg_heart] +is_a: GO:0060953 ! cardiac glial cell fate commitment +relationship: part_of GO:0060951 ! neural crest-derived cardiac glial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:15:04Z + +[Term] +id: GO:0060956 +name: endocardial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] +is_a: GO:0003348 ! cardiac endothelial cell differentiation +relationship: part_of GO:0003157 ! endocardium development +created_by: dph +creation_date: 2009-09-29T03:20:39Z + +[Term] +id: GO:0060957 +name: endocardial cell fate commitment +namespace: biological_process +def: "The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] +is_a: GO:0060839 ! endothelial cell fate commitment +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0060956 ! endocardial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:24:29Z + +[Term] +id: GO:0060958 +name: endocardial cell development +namespace: biological_process +def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] +is_a: GO:0001885 ! endothelial cell development +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0060956 ! endocardial cell differentiation +created_by: dph +creation_date: 2009-09-29T03:26:59Z + +[Term] +id: GO:0060959 +name: cardiac neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart] +synonym: "heart neuron development" EXACT [GOC:mtg_heart] +is_a: GO:0048666 ! neuron development +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0060945 ! cardiac neuron differentiation +created_by: dph +creation_date: 2009-09-30T10:14:56Z + +[Term] +id: GO:0060960 +name: cardiac neuron fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart." [GOC:mtg_heart] +synonym: "heart neuron fate commitment" EXACT [GOC:mtg_heart] +is_a: GO:0048663 ! neuron fate commitment +is_a: GO:0060911 ! cardiac cell fate commitment +relationship: part_of GO:0060945 ! cardiac neuron differentiation +created_by: dph +creation_date: 2009-09-30T10:23:47Z + +[Term] +id: GO:0060961 +name: phospholipase D inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate." [GOC:dph, GOC:tb] +is_a: GO:0004859 ! phospholipase inhibitor activity +relationship: negatively_regulates GO:0004630 ! phospholipase D activity +created_by: dph +creation_date: 2009-10-05T02:47:26Z + +[Term] +id: GO:0060962 +name: regulation of ribosomal protein gene transcription by RNA polymerase II +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II." [GOC:dph, GOC:tb, GOC:txnOH] +synonym: "regulation of ribosomal protein gene transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +created_by: dph +creation_date: 2009-10-05T03:00:40Z + +[Term] +id: GO:0060963 +name: positive regulation of ribosomal protein gene transcription by RNA polymerase II +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II." [GOC:dph, GOC:tb, GOC:txnOH] +synonym: "positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0060962 ! regulation of ribosomal protein gene transcription by RNA polymerase II +created_by: dph +creation_date: 2009-10-05T03:04:05Z + +[Term] +id: GO:0060964 +name: regulation of gene silencing by miRNA +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: RNA (often mRNA) cleavage or mRNA translational repression." [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:23985560, PMID:28379604] +synonym: "regulation of gene silencing by microRNA" EXACT [GOC:pr] +is_a: GO:0060147 ! regulation of posttranscriptional gene silencing +is_a: GO:0060966 ! regulation of gene silencing by RNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035195 ! gene silencing by miRNA +relationship: regulates GO:0035195 ! gene silencing by miRNA +created_by: dph +creation_date: 2009-10-05T03:10:28Z + +[Term] +id: GO:0060965 +name: negative regulation of gene silencing by miRNA +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of gene silencing by miRNA." [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:23985560, PMID:28379604] +synonym: "negative regulation of gene silencing by microRNA" EXACT [GOC:bf, GOC:pr] +is_a: GO:0060149 ! negative regulation of posttranscriptional gene silencing +is_a: GO:0060964 ! regulation of gene silencing by miRNA +is_a: GO:0060967 ! negative regulation of gene silencing by RNA +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035195 ! gene silencing by miRNA +relationship: negatively_regulates GO:0035195 ! gene silencing by miRNA +created_by: dph +creation_date: 2009-10-05T03:14:14Z + +[Term] +id: GO:0060966 +name: regulation of gene silencing by RNA +namespace: biological_process +def: "Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:tb] +is_a: GO:0060968 ! regulation of gene silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031047 ! gene silencing by RNA +relationship: regulates GO:0031047 ! gene silencing by RNA +created_by: dph +creation_date: 2009-10-05T03:17:02Z + +[Term] +id: GO:0060967 +name: negative regulation of gene silencing by RNA +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:tb] +is_a: GO:0060966 ! regulation of gene silencing by RNA +is_a: GO:0060969 ! negative regulation of gene silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031047 ! gene silencing by RNA +relationship: negatively_regulates GO:0031047 ! gene silencing by RNA +created_by: dph +creation_date: 2009-10-05T03:21:05Z + +[Term] +id: GO:0060968 +name: regulation of gene silencing +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation." [GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016458 ! gene silencing +relationship: regulates GO:0016458 ! gene silencing +created_by: dph +creation_date: 2009-10-05T03:23:56Z + +[Term] +id: GO:0060969 +name: negative regulation of gene silencing +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation." [GOC:dph, GOC:tb] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0060968 ! regulation of gene silencing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016458 ! gene silencing +relationship: negatively_regulates GO:0016458 ! gene silencing +created_by: dph +creation_date: 2009-10-05T03:26:19Z + +[Term] +id: GO:0060970 +name: embryonic heart tube dorsal/ventral pattern formation +namespace: biological_process +def: "The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis." [GOC:mtg_heart] +is_a: GO:0009953 ! dorsal/ventral pattern formation +relationship: part_of GO:0035050 ! embryonic heart tube development +created_by: dph +creation_date: 2009-10-06T10:14:53Z + +[Term] +id: GO:0060971 +name: embryonic heart tube left/right pattern formation +namespace: biological_process +def: "The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place." [GOC:mtg_heart] +is_a: GO:0060972 ! left/right pattern formation +relationship: part_of GO:0035050 ! embryonic heart tube development +created_by: dph +creation_date: 2009-10-06T10:22:11Z + +[Term] +id: GO:0060972 +name: left/right pattern formation +namespace: biological_process +def: "The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:mtg_heart] +is_a: GO:0003002 ! regionalization +created_by: dph +creation_date: 2009-10-06T10:25:58Z + +[Term] +id: GO:0060973 +name: cell migration involved in heart development +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart] +is_a: GO:0016477 ! cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0007507 ! heart development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-06T10:53:49Z + +[Term] +id: GO:0060974 +name: cell migration involved in heart formation +namespace: biological_process +def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart] +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0060914 ! heart formation +relationship: part_of GO:0060914 ! heart formation +created_by: dph +creation_date: 2009-10-06T10:56:33Z + +[Term] +id: GO:0060975 +name: cardioblast migration to the midline involved in heart field formation +namespace: biological_process +def: "The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] +synonym: "cardiac progenitor cell midline migration" EXACT [GOC:mtg_heart] +synonym: "cardioblast midline convergence" EXACT [GOC:mtg_heart] +is_a: GO:0003260 ! cardioblast migration +is_a: GO:0003318 ! cell migration to the midline involved in heart development +relationship: part_of GO:0060029 ! convergent extension involved in organogenesis +created_by: dph +creation_date: 2009-10-06T10:59:36Z + +[Term] +id: GO:0060976 +name: coronary vasculature development +namespace: biological_process +def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart] +synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart] +synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart] +synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart] +synonym: "heart blood vessel development" EXACT [GOC:mtg_heart] +synonym: "heart vasculature development" EXACT [GOC:mtg_heart] +is_a: GO:0001568 ! blood vessel development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2009-10-06T12:15:23Z + +[Term] +id: GO:0060977 +name: coronary vasculature morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart] +synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart] +synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart] +synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] +synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart] +synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0048514 ! blood vessel morphogenesis +relationship: part_of GO:0060976 ! coronary vasculature development +created_by: dph +creation_date: 2009-10-06T12:28:23Z + +[Term] +id: GO:0060978 +name: angiogenesis involved in coronary vascular morphogenesis +namespace: biological_process +def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart] +synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart] +synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart] +synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart] +synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0001525 ! angiogenesis +intersection_of: GO:0001525 ! angiogenesis +intersection_of: part_of GO:0060976 ! coronary vasculature development +relationship: part_of GO:0060977 ! coronary vasculature morphogenesis +created_by: dph +creation_date: 2009-10-06T02:02:12Z + +[Term] +id: GO:0060979 +name: vasculogenesis involved in coronary vascular morphogenesis +namespace: biological_process +def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart] +synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart] +synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] +is_a: GO:0001570 ! vasculogenesis +intersection_of: GO:0001570 ! vasculogenesis +intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis +relationship: part_of GO:0060977 ! coronary vasculature morphogenesis +created_by: dph +creation_date: 2009-10-06T02:19:42Z + +[Term] +id: GO:0060980 +name: cell migration involved in coronary vasculogenesis +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart] +is_a: GO:0035441 ! cell migration involved in vasculogenesis +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis +relationship: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis +created_by: dph +creation_date: 2009-10-06T02:33:06Z + +[Term] +id: GO:0060981 +name: cell migration involved in coronary angiogenesis +namespace: biological_process +def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart] +is_a: GO:0060973 ! cell migration involved in heart development +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis +relationship: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis +created_by: dph +creation_date: 2009-10-06T02:49:12Z + +[Term] +id: GO:0060982 +name: coronary artery morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle." [GOC:mtg_heart] +is_a: GO:0048844 ! artery morphogenesis +is_a: GO:0060977 ! coronary vasculature morphogenesis +created_by: dph +creation_date: 2009-10-06T02:58:52Z + +[Term] +id: GO:0060983 +name: epicardium-derived cardiac vascular smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers." [GOC:mtg_heart] +is_a: GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: dph +creation_date: 2009-10-06T03:05:33Z + +[Term] +id: GO:0060984 +name: epicardium-derived cardiac vascular smooth muscle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state." [GOC:mtg_heart] +is_a: GO:0060948 ! cardiac vascular smooth muscle cell development +relationship: part_of GO:0060983 ! epicardium-derived cardiac vascular smooth muscle cell differentiation +created_by: dph +creation_date: 2009-10-06T03:07:09Z + +[Term] +id: GO:0060985 +name: epicardium-derived cardiac vascular smooth muscle cell fate commitment +namespace: biological_process +def: "The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell." [GOC:mtg_heart] +is_a: GO:0060949 ! cardiac vascular smooth muscle cell fate commitment +relationship: part_of GO:0060983 ! epicardium-derived cardiac vascular smooth muscle cell differentiation +created_by: dph +creation_date: 2009-10-06T03:11:11Z + +[Term] +id: GO:0060986 +name: endocrine hormone secretion +namespace: biological_process +def: "The regulated release of a hormone into the circulatory system." [GOC:dph] +is_a: GO:0046879 ! hormone secretion +relationship: part_of GO:0050886 ! endocrine process +created_by: dph +creation_date: 2010-01-11T09:03:48Z + +[Term] +id: GO:0060987 +name: lipid tube +namespace: cellular_component +def: "A macromolecular complex that contains a tube of lipid surrounded by a protein coat." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0032994 ! protein-lipid complex +created_by: dph +creation_date: 2010-01-11T01:54:25Z + +[Term] +id: GO:0060988 +name: lipid tube assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "lipid tubulation" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0065005 ! protein-lipid complex assembly +created_by: dph +creation_date: 2010-01-11T01:56:59Z + +[Term] +id: GO:0060989 +name: lipid tube assembly involved in organelle fusion +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "lipid tubulation involved in organelle fusion" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060988 ! lipid tube assembly +intersection_of: GO:0060988 ! lipid tube assembly +intersection_of: part_of GO:0048284 ! organelle fusion +relationship: part_of GO:0048284 ! organelle fusion +created_by: dph +creation_date: 2010-01-11T02:06:50Z + +[Term] +id: GO:0060990 +name: lipid tube assembly involved in organelle fission +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "lipid tubulation involved in organelle fission" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060988 ! lipid tube assembly +intersection_of: GO:0060988 ! lipid tube assembly +intersection_of: part_of GO:0048285 ! organelle fission +relationship: part_of GO:0048285 ! organelle fission +created_by: dph +creation_date: 2010-01-11T02:14:48Z + +[Term] +id: GO:0060991 +name: obsolete lipid tube assembly involved in cytokinesis +namespace: biological_process +def: "OBSOLETE. The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: This term was made obsolete because there is no evidence the process exists. +synonym: "lipid tube assembly involved in cytokinesis" EXACT [] +synonym: "lipid tubulation involved in cytokinesis" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_obsolete: true +created_by: dph +creation_date: 2010-01-11T02:22:25Z + +[Term] +id: GO:0060992 +name: response to fungicide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi." [GOC:dph] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0046677 ! response to antibiotic +created_by: dph +creation_date: 2010-01-13T08:05:58Z + +[Term] +id: GO:0060993 +name: kidney morphogenesis +namespace: biological_process +def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2010-01-19T08:16:55Z + +[Term] +id: GO:0060994 +name: regulation of transcription from RNA polymerase II promoter involved in kidney development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2010-01-19T08:24:46Z + +[Term] +id: GO:0060995 +name: cell-cell signaling involved in kidney development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10] +synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2010-01-19T08:33:40Z + +[Term] +id: GO:0060996 +name: dendritic spine development +namespace: biological_process +def: "The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0016358 ! dendrite development +created_by: dph +creation_date: 2010-01-20T09:06:33Z + +[Term] +id: GO:0060997 +name: dendritic spine morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph] +is_a: GO:0031175 ! neuron projection development +is_a: GO:0048812 ! neuron projection morphogenesis +is_a: GO:0097061 ! dendritic spine organization +relationship: part_of GO:0048813 ! dendrite morphogenesis +relationship: part_of GO:0060996 ! dendritic spine development +created_by: dph +creation_date: 2010-01-20T09:09:57Z + +[Term] +id: GO:0060998 +name: regulation of dendritic spine development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0050773 ! regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060996 ! dendritic spine development +relationship: regulates GO:0060996 ! dendritic spine development +created_by: dph +creation_date: 2010-01-20T09:17:06Z + +[Term] +id: GO:0060999 +name: positive regulation of dendritic spine development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0060998 ! regulation of dendritic spine development +is_a: GO:1900006 ! positive regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060996 ! dendritic spine development +relationship: positively_regulates GO:0060996 ! dendritic spine development +created_by: dph +creation_date: 2010-01-20T09:27:21Z + +[Term] +id: GO:0061000 +name: negative regulation of dendritic spine development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0060998 ! regulation of dendritic spine development +is_a: GO:2000171 ! negative regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060996 ! dendritic spine development +relationship: negatively_regulates GO:0060996 ! dendritic spine development +created_by: dph +creation_date: 2010-01-20T09:29:18Z + +[Term] +id: GO:0061001 +name: regulation of dendritic spine morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph] +is_a: GO:0048814 ! regulation of dendrite morphogenesis +is_a: GO:0060998 ! regulation of dendritic spine development +is_a: GO:0099175 ! regulation of postsynapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060997 ! dendritic spine morphogenesis +relationship: regulates GO:0060997 ! dendritic spine morphogenesis +created_by: dph +creation_date: 2010-01-20T09:31:52Z + +[Term] +id: GO:0061002 +name: negative regulation of dendritic spine morphogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph] +is_a: GO:0050774 ! negative regulation of dendrite morphogenesis +is_a: GO:0061000 ! negative regulation of dendritic spine development +is_a: GO:0061001 ! regulation of dendritic spine morphogenesis +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060997 ! dendritic spine morphogenesis +relationship: negatively_regulates GO:0060997 ! dendritic spine morphogenesis +created_by: dph +creation_date: 2010-01-20T09:34:49Z + +[Term] +id: GO:0061003 +name: positive regulation of dendritic spine morphogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission." [GOC:dph] +is_a: GO:0050775 ! positive regulation of dendrite morphogenesis +is_a: GO:0060999 ! positive regulation of dendritic spine development +is_a: GO:0061001 ! regulation of dendritic spine morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060997 ! dendritic spine morphogenesis +relationship: positively_regulates GO:0060997 ! dendritic spine morphogenesis +created_by: dph +creation_date: 2010-01-20T09:36:54Z + +[Term] +id: GO:0061004 +name: pattern specification involved in kidney development +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10] +synonym: "kidney pattern formation" RELATED [GOC:mtg_kidney_jan10] +synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10] +synonym: "pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0007389 ! pattern specification process +intersection_of: GO:0007389 ! pattern specification process +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +relationship: part_of GO:0072048 ! renal system pattern specification +created_by: dph +creation_date: 2010-01-21T09:05:54Z + +[Term] +id: GO:0061005 +name: cell differentiation involved in kidney development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0030154 ! cell differentiation +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2010-01-21T09:13:55Z + +[Term] +id: GO:0061006 +name: regulation of cell proliferation involved in kidney morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0042127 ! regulation of cell population proliferation +intersection_of: part_of GO:0060993 ! kidney morphogenesis +relationship: part_of GO:0060993 ! kidney morphogenesis +created_by: dph +creation_date: 2010-01-21T11:25:23Z + +[Term] +id: GO:0061007 +name: hepaticobiliary system process +namespace: biological_process +def: "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] +synonym: "hepatobiliary system process" EXACT [GOC:dph] +is_a: GO:0003008 ! system process +created_by: dph +creation_date: 2010-01-22T09:09:10Z + +[Term] +id: GO:0061008 +name: hepaticobiliary system development +namespace: biological_process +def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] +synonym: "hepatobiliary system development" EXACT [GOC:dph] +is_a: GO:0048731 ! system development +created_by: dph +creation_date: 2010-01-22T09:11:59Z + +[Term] +id: GO:0061009 +name: common bile duct development +namespace: biological_process +def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine." [PMID:20614624] +synonym: "bile duct development" EXACT [GOC:dph] +synonym: "CBD development" EXACT [PMID:20614624] +synonym: "EHBD development" BROAD [PMID:20614624] +synonym: "extrahepatic bile duct development" BROAD [PMID:20614624] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0061008 ! hepaticobiliary system development +created_by: dph +creation_date: 2010-01-22T09:17:13Z + +[Term] +id: GO:0061010 +name: gall bladder development +namespace: biological_process +def: "The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile." [GOC:dph] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0061008 ! hepaticobiliary system development +created_by: dph +creation_date: 2010-01-22T09:38:44Z + +[Term] +id: GO:0061011 +name: hepatic duct development +namespace: biological_process +def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624] +is_a: GO:0061009 ! common bile duct development +created_by: dph +creation_date: 2010-01-22T09:44:39Z + +[Term] +id: GO:0061013 +name: regulation of mRNA catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of mRNA decay" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006402 ! mRNA catabolic process +relationship: regulates GO:0006402 ! mRNA catabolic process +created_by: dph +creation_date: 2010-01-29T01:48:10Z + +[Term] +id: GO:0061014 +name: positive regulation of mRNA catabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "positive regulation of mRNA decay" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0061013 ! regulation of mRNA catabolic process +is_a: GO:1903313 ! positive regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006402 ! mRNA catabolic process +relationship: positively_regulates GO:0006402 ! mRNA catabolic process +created_by: dph +creation_date: 2010-01-29T01:58:03Z + +[Term] +id: GO:0061015 +name: snRNA import into nucleus +namespace: biological_process +def: "The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0006404 ! RNA import into nucleus +is_a: GO:0051030 ! snRNA transport +created_by: dph +creation_date: 2010-01-29T02:36:00Z + +[Term] +id: GO:0061016 +name: snRNA localization to Cajal body +namespace: biological_process +def: "The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090670 ! RNA localization to Cajal body +created_by: dph +creation_date: 2010-01-29T02:40:50Z + +[Term] +id: GO:0061017 +name: hepatoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0048863 ! stem cell differentiation +relationship: part_of GO:0001889 ! liver development +created_by: dph +creation_date: 2010-02-02T09:08:03Z + +[Term] +id: GO:0061024 +name: membrane organization +namespace: biological_process +alt_id: GO:0016044 +alt_id: GO:0044802 +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb] +subset: goslim_chembl +subset: goslim_drosophila +subset: goslim_generic +subset: goslim_pir +subset: goslim_pombe +synonym: "cellular membrane organisation" EXACT [] +synonym: "cellular membrane organization" EXACT [] +synonym: "membrane organisation" EXACT [GOC:mah] +synonym: "membrane organization and biogenesis" RELATED [GOC:mah] +synonym: "single-organism membrane organization" RELATED [] +is_a: GO:0016043 ! cellular component organization +created_by: jl +creation_date: 2010-02-08T02:43:11Z + +[Term] +id: GO:0061025 +name: membrane fusion +namespace: biological_process +alt_id: GO:0006944 +alt_id: GO:0044801 +def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb] +subset: goslim_yeast +synonym: "cellular membrane fusion" EXACT [] +synonym: "single-organism membrane fusion" RELATED [] +xref: Wikipedia:Lipid_bilayer_fusion +is_a: GO:0061024 ! membrane organization +created_by: jl +creation_date: 2010-02-08T02:48:06Z + +[Term] +id: GO:0061026 +name: cardiac muscle tissue regeneration +namespace: biological_process +def: "The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage." [GOC:dph] +is_a: GO:0042246 ! tissue regeneration +created_by: dph +creation_date: 2010-02-09T08:25:51Z + +[Term] +id: GO:0061027 +name: umbilical cord development +namespace: biological_process +def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph] +is_a: GO:0048856 ! anatomical structure development +created_by: dph +creation_date: 2010-02-09T09:09:22Z + +[Term] +id: GO:0061028 +name: establishment of endothelial barrier +namespace: biological_process +def: "The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition." [GOC:dph] +is_a: GO:0001885 ! endothelial cell development +created_by: dph +creation_date: 2010-02-09T09:26:59Z + +[Term] +id: GO:0061029 +name: eyelid development in camera-type eye +namespace: biological_process +def: "The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043010 ! camera-type eye development +created_by: dph +creation_date: 2010-02-09T09:36:11Z + +[Term] +id: GO:0061030 +name: epithelial cell differentiation involved in mammary gland alveolus development +namespace: biological_process +def: "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus." [GOC:dph, GOC:yaf] +is_a: GO:0060644 ! mammary gland epithelial cell differentiation +intersection_of: GO:0030855 ! epithelial cell differentiation +intersection_of: part_of GO:0060749 ! mammary gland alveolus development +relationship: part_of GO:0060749 ! mammary gland alveolus development +created_by: dph +creation_date: 2010-02-09T09:43:00Z + +[Term] +id: GO:0061031 +name: endodermal digestive tract morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm." [GOC:dph, GOC:yaf] +is_a: GO:0048546 ! digestive tract morphogenesis +created_by: dph +creation_date: 2010-02-09T09:46:43Z + +[Term] +id: GO:0061032 +name: visceral serous pericardium development +namespace: biological_process +def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf] +synonym: "epicardium development" EXACT [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060039 ! pericardium development +created_by: dph +creation_date: 2010-02-09T09:52:49Z + +[Term] +id: GO:0061033 +name: secretion by lung epithelial cell involved in lung growth +namespace: biological_process +def: "The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development." [GOC:dph] +synonym: "fetal lung liquid secretion" RELATED [GOC:dph] +is_a: GO:0032940 ! secretion by cell +relationship: part_of GO:0060437 ! lung growth +created_by: dph +creation_date: 2010-02-09T10:02:55Z + +[Term] +id: GO:0061034 +name: olfactory bulb mitral cell layer development +namespace: biological_process +def: "The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021772 ! olfactory bulb development +created_by: dph +creation_date: 2010-02-09T03:30:23Z + +[Term] +id: GO:0061035 +name: regulation of cartilage development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051216 ! cartilage development +relationship: regulates GO:0051216 ! cartilage development +created_by: dph +creation_date: 2010-02-09T03:41:35Z + +[Term] +id: GO:0061036 +name: positive regulation of cartilage development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0061035 ! regulation of cartilage development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051216 ! cartilage development +relationship: positively_regulates GO:0051216 ! cartilage development +created_by: dph +creation_date: 2010-02-09T03:41:35Z + +[Term] +id: GO:0061037 +name: negative regulation of cartilage development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0061035 ! regulation of cartilage development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051216 ! cartilage development +relationship: negatively_regulates GO:0051216 ! cartilage development +created_by: dph +creation_date: 2010-02-09T03:41:35Z + +[Term] +id: GO:0061038 +name: uterus morphogenesis +namespace: biological_process +def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0060065 ! uterus development +created_by: dph +creation_date: 2010-02-22T11:12:35Z + +[Term] +id: GO:0061040 +name: female gonad morphogenesis +namespace: biological_process +def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph] +synonym: "ovary morphogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0035262 ! gonad morphogenesis +relationship: part_of GO:0008585 ! female gonad development +created_by: dph +creation_date: 2010-02-22T11:29:28Z + +[Term] +id: GO:0061041 +name: regulation of wound healing +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:BHF, GOC:dph] +is_a: GO:1903034 ! regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042060 ! wound healing +relationship: regulates GO:0042060 ! wound healing +created_by: dph +creation_date: 2010-02-25T10:14:37Z + +[Term] +id: GO:0061042 +name: vascular wound healing +namespace: biological_process +def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:BHF, GOC:dph] +is_a: GO:0060055 ! angiogenesis involved in wound healing +created_by: dph +creation_date: 2010-02-25T10:18:26Z + +[Term] +id: GO:0061043 +name: regulation of vascular wound healing +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:dph] +is_a: GO:0045765 ! regulation of angiogenesis +is_a: GO:0061041 ! regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061042 ! vascular wound healing +relationship: regulates GO:0061042 ! vascular wound healing +created_by: dph +creation_date: 2010-02-25T10:21:59Z + +[Term] +id: GO:0061044 +name: negative regulation of vascular wound healing +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature." [GOC:BHF, GOC:dph] +is_a: GO:0016525 ! negative regulation of angiogenesis +is_a: GO:0061043 ! regulation of vascular wound healing +is_a: GO:0061045 ! negative regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061042 ! vascular wound healing +relationship: negatively_regulates GO:0061042 ! vascular wound healing +created_by: dph +creation_date: 2010-02-25T10:24:28Z + +[Term] +id: GO:0061045 +name: negative regulation of wound healing +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:dph] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:1903035 ! negative regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042060 ! wound healing +relationship: negatively_regulates GO:0042060 ! wound healing +created_by: dph +creation_date: 2010-02-25T10:33:30Z + +[Term] +id: GO:0061046 +name: regulation of branching involved in lung morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +relationship: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +created_by: dph +creation_date: 2010-02-25T10:41:38Z + +[Term] +id: GO:0061047 +name: positive regulation of branching involved in lung morphogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] +is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +relationship: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +created_by: dph +creation_date: 2010-02-25T10:50:01Z + +[Term] +id: GO:0061048 +name: negative regulation of branching involved in lung morphogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] +is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +relationship: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis +created_by: dph +creation_date: 2010-02-25T10:51:31Z + +[Term] +id: GO:0061049 +name: cell growth involved in cardiac muscle cell development +namespace: biological_process +def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] +synonym: "cardiac muscle cell hypertrophy" RELATED [GOC:dph] +synonym: "cardiomyocyte growth" RELATED [GOC:dph] +synonym: "heart muscle cell growth" RELATED [GOC:dph] +is_a: GO:0048588 ! developmental cell growth +intersection_of: GO:0016049 ! cell growth +intersection_of: part_of GO:0055013 ! cardiac muscle cell development +relationship: part_of GO:0003301 ! physiological cardiac muscle hypertrophy +relationship: part_of GO:0055013 ! cardiac muscle cell development +created_by: dph +creation_date: 2010-02-25T12:56:07Z + +[Term] +id: GO:0061050 +name: regulation of cell growth involved in cardiac muscle cell development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy +is_a: GO:0055021 ! regulation of cardiac muscle tissue growth +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +relationship: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +created_by: dph +creation_date: 2010-02-25T01:05:16Z + +[Term] +id: GO:0061051 +name: positive regulation of cell growth involved in cardiac muscle cell development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] +is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth +is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development +is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +relationship: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +created_by: dph +creation_date: 2010-02-25T01:08:08Z + +[Term] +id: GO:0061052 +name: negative regulation of cell growth involved in cardiac muscle cell development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] +is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth +is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development +is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +relationship: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development +created_by: dph +creation_date: 2010-02-25T01:11:30Z + +[Term] +id: GO:0061053 +name: somite development +namespace: biological_process +def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0009790 ! embryo development +created_by: dph +creation_date: 2010-03-02T12:05:13Z + +[Term] +id: GO:0061054 +name: dermatome development +namespace: biological_process +def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061053 ! somite development +created_by: dph +creation_date: 2010-03-02T12:07:37Z + +[Term] +id: GO:0061055 +name: myotome development +namespace: biological_process +def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061053 ! somite development +created_by: dph +creation_date: 2010-03-02T12:11:01Z + +[Term] +id: GO:0061056 +name: sclerotome development +namespace: biological_process +def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0061053 ! somite development +created_by: dph +creation_date: 2010-03-02T12:12:40Z + +[Term] +id: GO:0061057 +name: peptidoglycan recognition protein signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides." [GOC:dph, PMID:18688280] +synonym: "Imd signaling pathway" EXACT [GOC:dph] +synonym: "Imd signalling pathway" EXACT [GOC:dph] +synonym: "immune deficiency pathway" RELATED [GOC:dph] +synonym: "immune deficiency signaling pathway" RELATED [GOC:dph] +synonym: "PGRP signaling pathway" RELATED [GOC:dph] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0042742 ! defense response to bacterium +created_by: dph +creation_date: 2010-03-02T12:20:10Z + +[Term] +id: GO:0061058 +name: regulation of peptidoglycan recognition protein signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph] +synonym: "regulation of peptidoglycan recognition protein signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +relationship: regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +created_by: dph +creation_date: 2010-03-02T12:35:40Z + +[Term] +id: GO:0061059 +name: positive regulation of peptidoglycan recognition protein signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph] +synonym: "positive regulation of peptidoglycan recognition protein signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0061058 ! regulation of peptidoglycan recognition protein signaling pathway +is_a: GO:1900426 ! positive regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +relationship: positively_regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +created_by: dph +creation_date: 2010-03-02T12:37:44Z + +[Term] +id: GO:0061060 +name: negative regulation of peptidoglycan recognition protein signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway." [GOC:dph] +synonym: "negative regulation of peptidoglycan recognition protein signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0061058 ! regulation of peptidoglycan recognition protein signaling pathway +is_a: GO:1900425 ! negative regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +relationship: negatively_regulates GO:0061057 ! peptidoglycan recognition protein signaling pathway +created_by: dph +creation_date: 2010-03-02T12:38:42Z + +[Term] +id: GO:0061061 +name: muscle structure development +namespace: biological_process +def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph] +subset: goslim_drosophila +is_a: GO:0048856 ! anatomical structure development +created_by: dph +creation_date: 2010-03-09T08:55:14Z + +[Term] +id: GO:0061062 +name: regulation of nematode larval development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002119 ! nematode larval development +relationship: regulates GO:0002119 ! nematode larval development +created_by: dph +creation_date: 2010-03-11T12:59:21Z + +[Term] +id: GO:0061063 +name: positive regulation of nematode larval development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0061062 ! regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002119 ! nematode larval development +relationship: positively_regulates GO:0002119 ! nematode larval development +created_by: dph +creation_date: 2010-03-11T01:03:34Z + +[Term] +id: GO:0061064 +name: negative regulation of nematode larval development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0061062 ! regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002119 ! nematode larval development +relationship: negatively_regulates GO:0002119 ! nematode larval development +created_by: dph +creation_date: 2010-03-11T01:04:39Z + +[Term] +id: GO:0061065 +name: regulation of dauer larval development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv] +is_a: GO:0061062 ! regulation of nematode larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0040024 ! dauer larval development +relationship: regulates GO:0040024 ! dauer larval development +created_by: dph +creation_date: 2010-03-11T01:07:07Z + +[Term] +id: GO:0061066 +name: positive regulation of dauer larval development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv] +is_a: GO:0061063 ! positive regulation of nematode larval development +is_a: GO:0061065 ! regulation of dauer larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0040024 ! dauer larval development +relationship: positively_regulates GO:0040024 ! dauer larval development +created_by: dph +creation_date: 2010-03-11T01:09:11Z + +[Term] +id: GO:0061067 +name: negative regulation of dauer larval development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." [GOC:dph, GOC:kmv] +is_a: GO:0061064 ! negative regulation of nematode larval development +is_a: GO:0061065 ! regulation of dauer larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0040024 ! dauer larval development +relationship: negatively_regulates GO:0040024 ! dauer larval development +created_by: dph +creation_date: 2010-03-11T01:10:23Z + +[Term] +id: GO:0061068 +name: urethra development +namespace: biological_process +def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0072001 ! renal system development +created_by: dph +creation_date: 2010-03-12T08:24:52Z + +[Term] +id: GO:0061069 +name: male urethra development +namespace: biological_process +def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph] +is_a: GO:0061068 ! urethra development +created_by: dph +creation_date: 2010-03-12T08:28:19Z + +[Term] +id: GO:0061070 +name: female urethra development +namespace: biological_process +def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph] +is_a: GO:0061068 ! urethra development +created_by: dph +creation_date: 2010-03-12T08:29:43Z + +[Term] +id: GO:0061071 +name: urethra epithelium development +namespace: biological_process +def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph] +is_a: GO:0035295 ! tube development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0061068 ! urethra development +created_by: dph +creation_date: 2010-03-12T08:36:53Z + +[Term] +id: GO:0061072 +name: iris morphogenesis +namespace: biological_process +def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048593 ! camera-type eye morphogenesis +created_by: dph +creation_date: 2010-03-16T10:48:42Z + +[Term] +id: GO:0061073 +name: ciliary body morphogenesis +namespace: biological_process +def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0048593 ! camera-type eye morphogenesis +created_by: dph +creation_date: 2010-03-16T10:55:19Z + +[Term] +id: GO:0061074 +name: regulation of neural retina development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] +is_a: GO:1902866 ! regulation of retina development in camera-type eye +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003407 ! neural retina development +relationship: regulates GO:0003407 ! neural retina development +created_by: dph +creation_date: 2010-03-16T11:47:05Z + +[Term] +id: GO:0061075 +name: positive regulation of neural retina development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] +is_a: GO:0061074 ! regulation of neural retina development +is_a: GO:1902868 ! positive regulation of retina development in camera-type eye +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003407 ! neural retina development +relationship: positively_regulates GO:0003407 ! neural retina development +created_by: dph +creation_date: 2010-03-16T11:59:48Z + +[Term] +id: GO:0061076 +name: negative regulation of neural retina development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] +is_a: GO:0061074 ! regulation of neural retina development +is_a: GO:1902867 ! negative regulation of retina development in camera-type eye +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003407 ! neural retina development +relationship: negatively_regulates GO:0003407 ! neural retina development +created_by: dph +creation_date: 2010-03-16T12:46:11Z + +[Term] +id: GO:0061077 +name: chaperone-mediated protein folding +namespace: biological_process +def: "The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone." [GOC:dph, GOC:vw] +is_a: GO:0006457 ! protein folding +created_by: dph +creation_date: 2010-04-06T03:28:55Z + +[Term] +id: GO:0061078 +name: positive regulation of prostaglandin secretion involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response." [GOC:BHF, GOC:dph] +synonym: "positive regulation of prostaglandin secretion during immune response" RELATED [GOC:dph] +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +is_a: GO:0032308 ! positive regulation of prostaglandin secretion +is_a: GO:0050778 ! positive regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090323 ! prostaglandin secretion involved in immune response +relationship: positively_regulates GO:0090323 ! prostaglandin secretion involved in immune response +created_by: dph +creation_date: 2010-04-08T01:53:45Z + +[Term] +id: GO:0061079 +name: left horn of sinus venosus development +namespace: biological_process +def: "The progression of the left horn of the sinus venosus from its initial formation to the mature structure." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0003235 ! sinus venosus development +created_by: dph +creation_date: 2010-04-08T02:40:27Z + +[Term] +id: GO:0061080 +name: right horn of sinus venosus development +namespace: biological_process +def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0003235 ! sinus venosus development +created_by: dph +creation_date: 2010-04-08T02:45:10Z + +[Term] +id: GO:0061081 +name: positive regulation of myeloid leukocyte cytokine production involved in immune response +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response." [GOC:BHF, GOC:dph] +synonym: "positive regulation of myeloid cell cytokine production involved in immune response" RELATED [GOC:dph] +is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061082 ! myeloid leukocyte cytokine production +relationship: positively_regulates GO:0061082 ! myeloid leukocyte cytokine production +created_by: dph +creation_date: 2010-04-13T11:26:41Z + +[Term] +id: GO:0061082 +name: myeloid leukocyte cytokine production +namespace: biological_process +def: "Any process that contributes to cytokine production by a myeloid cell." [GOC:dph] +is_a: GO:0002367 ! cytokine production involved in immune response +created_by: dph +creation_date: 2010-04-13T11:29:42Z + +[Term] +id: GO:0061083 +name: regulation of protein refolding +namespace: biological_process +def: "Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones." [GOC:dph, GOC:tb] +is_a: GO:1903332 ! regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042026 ! protein refolding +relationship: regulates GO:0042026 ! protein refolding +created_by: dph +creation_date: 2010-04-26T01:07:54Z + +[Term] +id: GO:0061084 +name: negative regulation of protein refolding +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0061083 ! regulation of protein refolding +is_a: GO:1903333 ! negative regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042026 ! protein refolding +relationship: negatively_regulates GO:0042026 ! protein refolding +created_by: dph +creation_date: 2010-04-26T01:11:29Z + +[Term] +id: GO:0061085 +name: regulation of histone H3-K27 methylation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070734 ! histone H3-K27 methylation +relationship: regulates GO:0070734 ! histone H3-K27 methylation +created_by: dph +creation_date: 2010-04-26T01:23:52Z + +[Term] +id: GO:0061086 +name: negative regulation of histone H3-K27 methylation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb] +is_a: GO:0031061 ! negative regulation of histone methylation +is_a: GO:0061085 ! regulation of histone H3-K27 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070734 ! histone H3-K27 methylation +relationship: negatively_regulates GO:0070734 ! histone H3-K27 methylation +created_by: dph +creation_date: 2010-04-26T01:23:52Z + +[Term] +id: GO:0061087 +name: positive regulation of histone H3-K27 methylation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone." [GOC:dph, GOC:tb] +is_a: GO:0031062 ! positive regulation of histone methylation +is_a: GO:0061085 ! regulation of histone H3-K27 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070734 ! histone H3-K27 methylation +relationship: positively_regulates GO:0070734 ! histone H3-K27 methylation +created_by: dph +creation_date: 2010-04-26T01:23:52Z + +[Term] +id: GO:0061088 +name: regulation of sequestering of zinc ion +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050801 ! ion homeostasis +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032119 ! sequestering of zinc ion +relationship: regulates GO:0032119 ! sequestering of zinc ion +created_by: dph +creation_date: 2010-04-26T01:38:53Z + +[Term] +id: GO:0061089 +name: negative regulation of sequestering of zinc ion +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0061088 ! regulation of sequestering of zinc ion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032119 ! sequestering of zinc ion +relationship: negatively_regulates GO:0032119 ! sequestering of zinc ion +created_by: dph +creation_date: 2010-04-26T01:38:53Z + +[Term] +id: GO:0061090 +name: positive regulation of sequestering of zinc ion +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0061088 ! regulation of sequestering of zinc ion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032119 ! sequestering of zinc ion +relationship: positively_regulates GO:0032119 ! sequestering of zinc ion +created_by: dph +creation_date: 2010-04-26T01:38:53Z + +[Term] +id: GO:0061091 +name: regulation of phospholipid translocation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0097035 ! regulation of membrane lipid distribution +is_a: GO:2001138 ! regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045332 ! phospholipid translocation +relationship: regulates GO:0045332 ! phospholipid translocation +created_by: dph +creation_date: 2010-04-26T01:54:22Z + +[Term] +id: GO:0061092 +name: positive regulation of phospholipid translocation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0061091 ! regulation of phospholipid translocation +is_a: GO:2001140 ! positive regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045332 ! phospholipid translocation +relationship: positively_regulates GO:0045332 ! phospholipid translocation +created_by: dph +creation_date: 2010-04-26T01:54:22Z + +[Term] +id: GO:0061093 +name: negative regulation of phospholipid translocation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer." [GOC:dph, GOC:jh, GOC:tb, PMID:19966303] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0061091 ! regulation of phospholipid translocation +is_a: GO:2001139 ! negative regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045332 ! phospholipid translocation +relationship: negatively_regulates GO:0045332 ! phospholipid translocation +created_by: dph +creation_date: 2010-04-26T01:54:22Z + +[Term] +id: GO:0061094 +name: regulation of turning behavior involved in mating +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb] +is_a: GO:1902435 ! regulation of male mating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034607 ! turning behavior involved in mating +relationship: regulates GO:0034607 ! turning behavior involved in mating +created_by: dph +creation_date: 2010-04-26T02:12:24Z + +[Term] +id: GO:0061095 +name: positive regulation of turning behavior involved in mating +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb] +is_a: GO:0061094 ! regulation of turning behavior involved in mating +is_a: GO:1902437 ! positive regulation of male mating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034607 ! turning behavior involved in mating +relationship: positively_regulates GO:0034607 ! turning behavior involved in mating +created_by: dph +creation_date: 2010-04-26T02:12:24Z + +[Term] +id: GO:0061096 +name: negative regulation of turning behavior involved in mating +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail." [GOC:dph, GOC:tb] +is_a: GO:0061094 ! regulation of turning behavior involved in mating +is_a: GO:1902436 ! negative regulation of male mating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034607 ! turning behavior involved in mating +relationship: negatively_regulates GO:0034607 ! turning behavior involved in mating +created_by: dph +creation_date: 2010-04-26T02:12:24Z + +[Term] +id: GO:0061097 +name: regulation of protein tyrosine kinase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] +is_a: GO:0045859 ! regulation of protein kinase activity +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004713 ! protein tyrosine kinase activity +relationship: regulates GO:0004713 ! protein tyrosine kinase activity +created_by: dph +creation_date: 2010-04-26T02:34:53Z + +[Term] +id: GO:0061098 +name: positive regulation of protein tyrosine kinase activity +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] +is_a: GO:0045860 ! positive regulation of protein kinase activity +is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation +is_a: GO:0061097 ! regulation of protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004713 ! protein tyrosine kinase activity +relationship: positively_regulates GO:0004713 ! protein tyrosine kinase activity +created_by: dph +creation_date: 2010-04-26T02:34:53Z + +[Term] +id: GO:0061099 +name: negative regulation of protein tyrosine kinase activity +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation +is_a: GO:0061097 ! regulation of protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004713 ! protein tyrosine kinase activity +relationship: negatively_regulates GO:0004713 ! protein tyrosine kinase activity +created_by: dph +creation_date: 2010-04-26T02:34:53Z + +[Term] +id: GO:0061100 +name: lung neuroendocrine cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746] +is_a: GO:0061101 ! neuroendocrine cell differentiation +is_a: GO:0061140 ! lung secretory cell differentiation +created_by: dph +creation_date: 2010-04-27T03:28:46Z + +[Term] +id: GO:0061101 +name: neuroendocrine cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph] +is_a: GO:0060563 ! neuroepithelial cell differentiation +created_by: dph +creation_date: 2010-04-28T09:42:20Z + +[Term] +id: GO:0061102 +name: stomach neuroendocrine cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] +synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph] +is_a: GO:0061101 ! neuroendocrine cell differentiation +relationship: part_of GO:0062094 ! stomach development +created_by: dph +creation_date: 2010-04-28T09:47:07Z + +[Term] +id: GO:0061103 +name: carotid body glomus cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia." [GOC:dph, PMID:6243386] +is_a: GO:0061101 ! neuroendocrine cell differentiation +relationship: part_of GO:0048513 ! animal organ development +created_by: dph +creation_date: 2010-04-28T10:59:24Z + +[Term] +id: GO:0061104 +name: adrenal chromaffin cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles." [GOC:dph] +is_a: GO:0002067 ! glandular epithelial cell differentiation +is_a: GO:0061101 ! neuroendocrine cell differentiation +relationship: part_of GO:0030325 ! adrenal gland development +created_by: dph +creation_date: 2010-04-29T08:27:53Z + +[Term] +id: GO:0061105 +name: regulation of stomach neuroendocrine cell differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061102 ! stomach neuroendocrine cell differentiation +relationship: regulates GO:0061102 ! stomach neuroendocrine cell differentiation +created_by: dph +creation_date: 2010-04-29T12:19:37Z + +[Term] +id: GO:0061106 +name: negative regulation of stomach neuroendocrine cell differentiation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] +is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation +relationship: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation +created_by: dph +creation_date: 2010-04-29T12:23:05Z + +[Term] +id: GO:0061107 +name: seminal vesicle development +namespace: biological_process +def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph] +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0048732 ! gland development +created_by: dph +creation_date: 2010-04-30T10:17:30Z + +[Term] +id: GO:0061108 +name: seminal vesicle epithelium development +namespace: biological_process +def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0035295 ! tube development +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0061107 ! seminal vesicle development +created_by: dph +creation_date: 2010-04-30T10:19:54Z + +[Term] +id: GO:0061109 +name: dense core granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph] +synonym: "dense core granule organisation" EXACT [GOC:mah] +is_a: GO:0033363 ! secretory granule organization +created_by: dph +creation_date: 2010-05-01T09:34:37Z + +[Term] +id: GO:0061110 +name: dense core granule biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule." [GOC:dph] +is_a: GO:0044085 ! cellular component biogenesis +created_by: dph +creation_date: 2010-05-01T09:40:11Z + +[Term] +id: GO:0061111 +name: epithelial-mesenchymal cell signaling involved in lung development +namespace: biological_process +def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph] +synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah] +is_a: GO:0060495 ! cell-cell signaling involved in lung development +is_a: GO:0060684 ! epithelial-mesenchymal cell signaling +intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling +intersection_of: part_of GO:0030324 ! lung development +created_by: dph +creation_date: 2010-05-05T11:14:38Z + +[Term] +id: GO:0061112 +name: negative regulation of bud outgrowth involved in lung branching +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching." [GOC:dph] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0061048 ! negative regulation of branching involved in lung morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060447 ! bud outgrowth involved in lung branching +relationship: negatively_regulates GO:0060447 ! bud outgrowth involved in lung branching +created_by: dph +creation_date: 2010-05-05T11:20:42Z + +[Term] +id: GO:0061113 +name: pancreas morphogenesis +namespace: biological_process +def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0031016 ! pancreas development +created_by: dph +creation_date: 2010-05-05T11:55:30Z + +[Term] +id: GO:0061114 +name: branching involved in pancreas morphogenesis +namespace: biological_process +def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph] +is_a: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0061113 ! pancreas morphogenesis +relationship: part_of GO:0061113 ! pancreas morphogenesis +created_by: dph +creation_date: 2010-05-05T12:03:04Z + +[Term] +id: GO:0061115 +name: lung proximal/distal axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli." [GOC:dph] +is_a: GO:0009946 ! proximal/distal axis specification +is_a: GO:0060432 ! lung pattern specification process +created_by: dph +creation_date: 2010-05-10T12:30:40Z + +[Term] +id: GO:0061116 +name: ductus venosus closure +namespace: biological_process +def: "The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth." [GOC:dph] +is_a: GO:0048845 ! venous blood vessel morphogenesis +created_by: dph +creation_date: 2010-05-17T07:21:53Z + +[Term] +id: GO:0061117 +name: negative regulation of heart growth +namespace: biological_process +def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd] +is_a: GO:0046621 ! negative regulation of organ growth +is_a: GO:0060420 ! regulation of heart growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060419 ! heart growth +relationship: negatively_regulates GO:0060419 ! heart growth +created_by: dph +creation_date: 2010-05-17T07:31:28Z + +[Term] +id: GO:0061118 +name: regulation of positive chemotaxis to cAMP +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph] +is_a: GO:0050926 ! regulation of positive chemotaxis +relationship: regulates GO:0043327 ! chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T07:47:47Z + +[Term] +id: GO:0061119 +name: regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph, PMID:19684855] +is_a: GO:0061118 ! regulation of positive chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T07:53:58Z + +[Term] +id: GO:0061120 +name: regulation of positive chemotaxis to cAMP by DIF-1 +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061119 ! regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:10:20Z + +[Term] +id: GO:0061121 +name: regulation of positive chemotaxis to cAMP by DIF-2 +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061119 ! regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:16:21Z + +[Term] +id: GO:0061122 +name: positive regulation of positive chemotaxis to cAMP +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph] +is_a: GO:0050927 ! positive regulation of positive chemotaxis +is_a: GO:0061118 ! regulation of positive chemotaxis to cAMP +relationship: positively_regulates GO:0043327 ! chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T08:25:55Z + +[Term] +id: GO:0061123 +name: negative regulation of positive chemotaxis to cAMP +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP." [GOC:dph] +is_a: GO:0050928 ! negative regulation of positive chemotaxis +is_a: GO:0061118 ! regulation of positive chemotaxis to cAMP +relationship: negatively_regulates GO:0043327 ! chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T08:27:20Z + +[Term] +id: GO:0061124 +name: positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph] +is_a: GO:0061119 ! regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +is_a: GO:0061122 ! positive regulation of positive chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T08:33:40Z + +[Term] +id: GO:0061125 +name: negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions." [GOC:dph] +is_a: GO:0061119 ! regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +is_a: GO:0061123 ! negative regulation of positive chemotaxis to cAMP +created_by: dph +creation_date: 2010-05-17T08:36:55Z + +[Term] +id: GO:0061126 +name: positive regulation of positive chemotaxis to cAMP by DIF-1 +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061120 ! regulation of positive chemotaxis to cAMP by DIF-1 +is_a: GO:0061124 ! positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:41:04Z + +[Term] +id: GO:0061127 +name: negative regulation of positive chemotaxis to cAMP by DIF-1 +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061120 ! regulation of positive chemotaxis to cAMP by DIF-1 +is_a: GO:0061125 ! negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:45:03Z + +[Term] +id: GO:0061128 +name: positive regulation of chemotaxis to cAMP by DIF-2 +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061121 ! regulation of positive chemotaxis to cAMP by DIF-2 +is_a: GO:0061124 ! positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:48:17Z + +[Term] +id: GO:0061129 +name: negative regulation of positive chemotaxis to cAMP by DIF-2 +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone." [GOC:dph] +is_a: GO:0061121 ! regulation of positive chemotaxis to cAMP by DIF-2 +is_a: GO:0061125 ! negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone +created_by: dph +creation_date: 2010-05-17T08:50:33Z + +[Term] +id: GO:0061130 +name: pancreatic bud formation +namespace: biological_process +def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph] +is_a: GO:0048645 ! animal organ formation +is_a: GO:0061114 ! branching involved in pancreas morphogenesis +is_a: GO:0072175 ! epithelial tube formation +created_by: dph +creation_date: 2010-05-17T09:33:40Z + +[Term] +id: GO:0061131 +name: pancreas field specification +namespace: biological_process +def: "The process in which a specific region of the gut is delineated into the area in which the pancreas will develop." [GOC:dph] +is_a: GO:0010092 ! specification of animal organ identity +relationship: part_of GO:0061130 ! pancreatic bud formation +created_by: dph +creation_date: 2010-05-17T09:39:49Z + +[Term] +id: GO:0061132 +name: pancreas induction +namespace: biological_process +def: "The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas." [GOC:dph] +is_a: GO:0001759 ! organ induction +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905278 ! positive regulation of epithelial tube formation +intersection_of: GO:0001759 ! organ induction +intersection_of: positively_regulates GO:0061131 ! pancreas field specification +relationship: positively_regulates GO:0061131 ! pancreas field specification +created_by: dph +creation_date: 2010-05-17T09:45:32Z + +[Term] +id: GO:0061133 +name: endopeptidase activator activity +namespace: molecular_function +def: "Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides." [GOC:dph, GOC:tb] +is_a: GO:0016504 ! peptidase activator activity +is_a: GO:0061135 ! endopeptidase regulator activity +relationship: part_of GO:0010950 ! positive regulation of endopeptidase activity +relationship: positively_regulates GO:0004175 ! endopeptidase activity +created_by: dph +creation_date: 2010-05-17T01:08:29Z + +[Term] +id: GO:0061134 +name: peptidase regulator activity +namespace: molecular_function +def: "Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds." [GOC:dph, GOC:tb] +is_a: GO:0030234 ! enzyme regulator activity +relationship: has_part GO:0002020 ! protease binding +relationship: part_of GO:0052547 ! regulation of peptidase activity +relationship: regulates GO:0008233 ! peptidase activity +created_by: dph +creation_date: 2010-05-17T01:15:24Z + +[Term] +id: GO:0061135 +name: endopeptidase regulator activity +namespace: molecular_function +def: "Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides." [GOC:dph, GOC:tb] +is_a: GO:0061134 ! peptidase regulator activity +relationship: part_of GO:0052548 ! regulation of endopeptidase activity +relationship: regulates GO:0004175 ! endopeptidase activity +created_by: dph +creation_date: 2010-05-17T01:19:36Z + +[Term] +id: GO:0061136 +name: regulation of proteasomal protein catabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome." [GOC:dph, GOC:tb] +is_a: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010498 ! proteasomal protein catabolic process +relationship: regulates GO:0010498 ! proteasomal protein catabolic process +created_by: dph +creation_date: 2010-05-17T01:33:20Z + +[Term] +id: GO:0061137 +name: bud dilation +namespace: biological_process +def: "The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch." [GOC:dph] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0001763 ! morphogenesis of a branching structure +created_by: dph +creation_date: 2010-05-20T07:54:42Z + +[Term] +id: GO:0061138 +name: morphogenesis of a branching epithelium +namespace: biological_process +def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph] +is_a: GO:0001763 ! morphogenesis of a branching structure +is_a: GO:0002009 ! morphogenesis of an epithelium +created_by: dph +creation_date: 2010-05-25T09:05:34Z + +[Term] +id: GO:0061139 +name: bud field specification +namespace: biological_process +def: "The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:dph] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0061138 ! morphogenesis of a branching epithelium +created_by: dph +creation_date: 2010-05-25T09:21:01Z + +[Term] +id: GO:0061140 +name: lung secretory cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph] +is_a: GO:0060487 ! lung epithelial cell differentiation +created_by: dph +creation_date: 2010-05-25T09:28:53Z + +[Term] +id: GO:0061141 +name: lung ciliated cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] +is_a: GO:0060487 ! lung epithelial cell differentiation +created_by: dph +creation_date: 2010-05-25T09:31:14Z + +[Term] +id: GO:0061142 +name: mesothelial-mesenchymal cell signaling involved in early lung development +namespace: biological_process +def: "Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung." [GOC:dph] +synonym: "mesothelial-mesenchymal cell signalling involved in early lung development" EXACT [GOC:mah] +is_a: GO:0060495 ! cell-cell signaling involved in lung development +created_by: dph +creation_date: 2010-05-25T09:35:32Z + +[Term] +id: GO:0061143 +name: alveolar primary septum development +namespace: biological_process +def: "The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms." [GOC:dph] +is_a: GO:0060428 ! lung epithelium development +relationship: part_of GO:0060430 ! lung saccule development +created_by: dph +creation_date: 2010-05-25T10:21:27Z + +[Term] +id: GO:0061144 +name: alveolar secondary septum development +namespace: biological_process +def: "The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule." [GOC:dph] +is_a: GO:0060428 ! lung epithelium development +relationship: part_of GO:0060430 ! lung saccule development +created_by: dph +creation_date: 2010-05-25T10:43:55Z + +[Term] +id: GO:0061145 +name: lung smooth muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0048745 ! smooth muscle tissue development +relationship: part_of GO:0030324 ! lung development +created_by: dph +creation_date: 2010-05-25T10:46:35Z + +[Term] +id: GO:0061146 +name: Peyer's patch morphogenesis +namespace: biological_process +def: "The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes." [GOC:dph] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0048541 ! Peyer's patch development +created_by: dph +creation_date: 2010-05-26T06:46:23Z + +[Term] +id: GO:0061147 +name: endocardial endothelium development +namespace: biological_process +def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] +is_a: GO:0003158 ! endothelium development +relationship: part_of GO:0003157 ! endocardium development +created_by: dph +creation_date: 2010-06-03T09:15:31Z + +[Term] +id: GO:0061148 +name: extracellular matrix organization involved in endocardium development +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] +synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah] +is_a: GO:0030198 ! extracellular matrix organization +intersection_of: GO:0030198 ! extracellular matrix organization +intersection_of: part_of GO:0003157 ! endocardium development +relationship: part_of GO:0003157 ! endocardium development +created_by: dph +creation_date: 2010-06-03T09:18:02Z + +[Term] +id: GO:0061149 +name: BMP signaling pathway involved in ureter morphogenesis +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder." [GOC:dph, GOC:mtg_kidney_jan10] +synonym: "BMP signalling pathway involved in ureter morphogenesis" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0072197 ! ureter morphogenesis +relationship: part_of GO:0072197 ! ureter morphogenesis +created_by: dph +creation_date: 2010-06-02T09:11:46Z + +[Term] +id: GO:0061150 +name: renal system segmentation +namespace: biological_process +def: "The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis." [GOC:dph, GOC:yaf] +synonym: "urinary tract segmentation" EXACT [GOC:dph] +is_a: GO:0035282 ! segmentation +is_a: GO:0072048 ! renal system pattern specification +created_by: dph +creation_date: 2010-06-02T09:23:01Z + +[Term] +id: GO:0061151 +name: BMP signaling pathway involved in renal system segmentation +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system." [GOC:dph, GOC:yaf] +synonym: "BMP signalling pathway involved in renal system segmentation" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0061150 ! renal system segmentation +relationship: part_of GO:0061150 ! renal system segmentation +created_by: dph +creation_date: 2010-06-02T09:29:43Z + +[Term] +id: GO:0061152 +name: trachea submucosa development +namespace: biological_process +def: "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0060438 ! trachea development +created_by: dph +creation_date: 2010-06-07T09:58:40Z + +[Term] +id: GO:0061153 +name: trachea gland development +namespace: biological_process +def: "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection." [GOC:dph] +is_a: GO:0048732 ! gland development +relationship: part_of GO:0061152 ! trachea submucosa development +created_by: dph +creation_date: 2010-06-07T10:10:51Z + +[Term] +id: GO:0061154 +name: endothelial tube morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf] +is_a: GO:0003159 ! morphogenesis of an endothelium +is_a: GO:0060562 ! epithelial tube morphogenesis +created_by: dph +creation_date: 2010-06-15T09:05:00Z + +[Term] +id: GO:0061155 +name: pulmonary artery endothelial tube morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf] +is_a: GO:0061154 ! endothelial tube morphogenesis +relationship: part_of GO:0061156 ! pulmonary artery morphogenesis +created_by: dph +creation_date: 2010-06-15T09:09:04Z + +[Term] +id: GO:0061156 +name: pulmonary artery morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf] +is_a: GO:0048844 ! artery morphogenesis +created_by: dph +creation_date: 2010-06-15T09:13:47Z + +[Term] +id: GO:0061157 +name: mRNA destabilization +namespace: biological_process +def: "Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns." [GOC:dph, GOC:jh] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0043488 ! regulation of mRNA stability +is_a: GO:0050779 ! RNA destabilization +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +created_by: dph +creation_date: 2010-06-22T08:42:10Z + +[Term] +id: GO:0061158 +name: 3'-UTR-mediated mRNA destabilization +namespace: biological_process +def: "An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA." [GOC:dph, GOC:jh] +is_a: GO:0061157 ! mRNA destabilization +created_by: dph +creation_date: 2010-06-22T08:44:39Z + +[Term] +id: GO:0061159 +name: establishment of bipolar cell polarity involved in cell morphogenesis +namespace: biological_process +def: "The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw] +is_a: GO:0061171 ! establishment of bipolar cell polarity +intersection_of: GO:0061171 ! establishment of bipolar cell polarity +intersection_of: part_of GO:0000902 ! cell morphogenesis +relationship: part_of GO:0000902 ! cell morphogenesis +created_by: dph +creation_date: 2010-06-23T09:14:39Z + +[Term] +id: GO:0061160 +name: regulation of establishment of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell." [GOC:dph, GOC:vw] +is_a: GO:0061172 ! regulation of establishment of bipolar cell polarity +is_a: GO:2000100 ! regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-06-23T09:21:36Z + +[Term] +id: GO:0061161 +name: positive regulation of establishment of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell." [GOC:dph, GOC:vw] +is_a: GO:0061160 ! regulation of establishment of bipolar cell polarity regulating cell shape +is_a: GO:0061173 ! positive regulation of establishment of bipolar cell polarity +is_a: GO:2000247 ! positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-06-23T09:26:45Z + +[Term] +id: GO:0061162 +name: establishment of monopolar cell polarity +namespace: biological_process +def: "The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis." [GOC:dph, GOC:vw] +is_a: GO:0030010 ! establishment of cell polarity +is_a: GO:0061339 ! establishment or maintenance of monopolar cell polarity +created_by: dph +creation_date: 2010-06-23T09:30:59Z + +[Term] +id: GO:0061163 +name: endoplasmic reticulum polarization +namespace: biological_process +def: "The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell." [GOC:dph, GOC:vw] +is_a: GO:0007029 ! endoplasmic reticulum organization +is_a: GO:0007163 ! establishment or maintenance of cell polarity +created_by: dph +creation_date: 2010-06-25T09:51:48Z + +[Term] +id: GO:0061164 +name: transitional endoplasmic reticulum polarization at cell division site +namespace: biological_process +def: "The endoplasmic reticulum polarization process that results in the structure being polarized at the site of future cell division." [GOC:dph, GOC:vw] +is_a: GO:0061163 ! endoplasmic reticulum polarization +created_by: dph +creation_date: 2010-06-25T09:56:51Z + +[Term] +id: GO:0061165 +name: endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site +namespace: biological_process +def: "The process in which endoplasmic reticulum is transiently localized to the site where a cell will divide." [GOC:dph, GOC:vw] +synonym: "endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site" EXACT [GOC:mah] +synonym: "ER localization involved in ER polarization at cell division site" EXACT [GOC:dph] +is_a: GO:0051643 ! endoplasmic reticulum localization +intersection_of: GO:0051643 ! endoplasmic reticulum localization +intersection_of: part_of GO:0061164 ! transitional endoplasmic reticulum polarization at cell division site +relationship: part_of GO:0061164 ! transitional endoplasmic reticulum polarization at cell division site +created_by: dph +creation_date: 2010-06-25T10:11:09Z + +[Term] +id: GO:0061166 +name: establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site +namespace: biological_process +def: "The directed movement of the endoplasmic reticulum to the site where a cell will divide." [GOC:dph, GOC:vw] +synonym: "establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site" EXACT [GOC:mah] +is_a: GO:0051686 ! establishment of ER localization +is_a: GO:0061165 ! endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site +intersection_of: GO:0051686 ! establishment of ER localization +intersection_of: part_of GO:0061164 ! transitional endoplasmic reticulum polarization at cell division site +created_by: dph +creation_date: 2010-06-25T10:16:34Z + +[Term] +id: GO:0061167 +name: maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site +namespace: biological_process +def: "The process in which the endoplasmic reticulum is maintained at the site of cell division and is prevented from moving elsewhere." [GOC:dph, GOC:vw] +is_a: GO:0051685 ! maintenance of ER location +is_a: GO:0061165 ! endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site +intersection_of: GO:0051685 ! maintenance of ER location +intersection_of: part_of GO:0061164 ! transitional endoplasmic reticulum polarization at cell division site +created_by: dph +creation_date: 2010-06-25T10:18:36Z + +[Term] +id: GO:0061168 +name: regulation of hair follicle placode formation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051797 ! regulation of hair follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060789 ! hair follicle placode formation +relationship: regulates GO:0060789 ! hair follicle placode formation +created_by: dph +creation_date: 2010-06-25T01:03:29Z + +[Term] +id: GO:0061169 +name: positive regulation of hair placode formation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph] +is_a: GO:0051798 ! positive regulation of hair follicle development +is_a: GO:0061168 ! regulation of hair follicle placode formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060789 ! hair follicle placode formation +relationship: positively_regulates GO:0060789 ! hair follicle placode formation +created_by: dph +creation_date: 2010-06-25T01:08:50Z + +[Term] +id: GO:0061170 +name: negative regulation of hair follicle placode formation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud." [GOC:dph] +is_a: GO:0051799 ! negative regulation of hair follicle development +is_a: GO:0061168 ! regulation of hair follicle placode formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060789 ! hair follicle placode formation +relationship: negatively_regulates GO:0060789 ! hair follicle placode formation +created_by: dph +creation_date: 2010-06-25T01:10:48Z + +[Term] +id: GO:0061171 +name: establishment of bipolar cell polarity +namespace: biological_process +def: "The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw] +is_a: GO:0030010 ! establishment of cell polarity +created_by: dph +creation_date: 2010-06-30T08:49:38Z + +[Term] +id: GO:0061172 +name: regulation of establishment of bipolar cell polarity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane." [GOC:dph, GOC:vw] +is_a: GO:2000114 ! regulation of establishment of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061171 ! establishment of bipolar cell polarity +relationship: regulates GO:0061171 ! establishment of bipolar cell polarity +created_by: dph +creation_date: 2010-06-30T08:51:27Z + +[Term] +id: GO:0061173 +name: positive regulation of establishment of bipolar cell polarity +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity." [GOC:dph, GOC:vw] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0061172 ! regulation of establishment of bipolar cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061171 ! establishment of bipolar cell polarity +relationship: positively_regulates GO:0061171 ! establishment of bipolar cell polarity +created_by: dph +creation_date: 2010-06-30T08:59:20Z + +[Term] +id: GO:0061174 +name: type I terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc] +synonym: "type I terminal button" EXACT [GOC:dph] +is_a: GO:0043195 ! terminal bouton +created_by: dph +creation_date: 2010-07-13T09:13:05Z + +[Term] +id: GO:0061175 +name: type II terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc] +synonym: "type II terminal button" EXACT [GOC:dph] +is_a: GO:0043195 ! terminal bouton +created_by: dph +creation_date: 2010-07-13T09:18:01Z + +[Term] +id: GO:0061176 +name: type Ib terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons." [GOC:dph, GOC:mc] +synonym: "type Ib terminal button" EXACT [GOC:dph] +is_a: GO:0061174 ! type I terminal bouton +created_by: dph +creation_date: 2010-07-13T09:20:04Z + +[Term] +id: GO:0061177 +name: type Is terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons." [GOC:dph, GOC:mc] +synonym: "type Is terminal button" RELATED [GOC:dph] +is_a: GO:0061174 ! type I terminal bouton +created_by: dph +creation_date: 2010-07-13T09:25:15Z + +[Term] +id: GO:0061178 +name: regulation of insulin secretion involved in cellular response to glucose stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph] +synonym: "regulation of insulin secretion in response to glucose" EXACT [GOC:dph] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050796 ! regulation of insulin secretion +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +relationship: regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +created_by: dph +creation_date: 2010-07-13T09:38:42Z + +[Term] +id: GO:0061179 +name: negative regulation of insulin secretion involved in cellular response to glucose stimulus +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." [GOC:BHF, GOC:dph] +synonym: "negative regulation of insulin secretion in response to glucose" RELATED [GOC:dph] +synonym: "negative regulation of insulin secretion involved in cellular response to glucose" EXACT [GOC:bf] +is_a: GO:0046676 ! negative regulation of insulin secretion +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0061178 ! regulation of insulin secretion involved in cellular response to glucose stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +relationship: negatively_regulates GO:0035773 ! insulin secretion involved in cellular response to glucose stimulus +created_by: dph +creation_date: 2010-07-13T09:41:46Z + +[Term] +id: GO:0061180 +name: mammary gland epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, GOC:yaf] +synonym: "breast epithelium development" EXACT [GOC:dph] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2010-07-14T08:18:24Z + +[Term] +id: GO:0061181 +name: regulation of chondrocyte development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] +is_a: GO:0032330 ! regulation of chondrocyte differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002063 ! chondrocyte development +relationship: regulates GO:0002063 ! chondrocyte development +created_by: dph +creation_date: 2010-07-14T08:28:52Z + +[Term] +id: GO:0061182 +name: negative regulation of chondrocyte development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0032331 ! negative regulation of chondrocyte differentiation +is_a: GO:0061181 ! regulation of chondrocyte development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002063 ! chondrocyte development +relationship: negatively_regulates GO:0002063 ! chondrocyte development +created_by: dph +creation_date: 2010-07-14T08:33:05Z + +[Term] +id: GO:0061183 +name: regulation of dermatome development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061054 ! dermatome development +relationship: regulates GO:0061054 ! dermatome development +created_by: dph +creation_date: 2010-07-14T08:40:26Z + +[Term] +id: GO:0061184 +name: positive regulation of dermatome development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0061183 ! regulation of dermatome development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061054 ! dermatome development +relationship: positively_regulates GO:0061054 ! dermatome development +created_by: dph +creation_date: 2010-07-14T08:42:03Z + +[Term] +id: GO:0061185 +name: negative regulation of dermatome development +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0061183 ! regulation of dermatome development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061054 ! dermatome development +relationship: negatively_regulates GO:0061054 ! dermatome development +created_by: dph +creation_date: 2010-07-14T08:43:08Z + +[Term] +id: GO:0061186 +name: negative regulation of silent mating-type cassette heterochromatin assembly +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin." [GOC:dph, PMID:10388812] +synonym: "negative regulation of chromatin silencing at silent mating-type cassette" EXACT [] +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +is_a: GO:0090054 ! regulation of silent mating-type cassette heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +relationship: negatively_regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: dph +creation_date: 2010-07-14T08:59:11Z + +[Term] +id: GO:0061187 +name: regulation of ribosomal DNA heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin." [GOC:dph, PMID:10388812] +synonym: "regulation of chromatin silencing at rDNA" BROAD [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000183 ! rDNA heterochromatin assembly +relationship: regulates GO:0000183 ! rDNA heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19238 xsd:anyURI +created_by: dph +creation_date: 2010-07-14T09:04:16Z + +[Term] +id: GO:0061188 +name: negative regulation of ribosomal DNA heterochromatin assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin." [GOC:dph, PMID:10388812] +synonym: "negative regulation of chromatin silencing at rDNA" BROAD [] +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +is_a: GO:0061187 ! regulation of ribosomal DNA heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000183 ! rDNA heterochromatin assembly +relationship: negatively_regulates GO:0000183 ! rDNA heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19238 xsd:anyURI +created_by: dph +creation_date: 2010-07-14T09:07:59Z + +[Term] +id: GO:0061189 +name: positive regulation of sclerotome development +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0061190 ! regulation of sclerotome development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061056 ! sclerotome development +relationship: positively_regulates GO:0061056 ! sclerotome development +created_by: dph +creation_date: 2010-07-14T09:17:23Z + +[Term] +id: GO:0061190 +name: regulation of sclerotome development +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061056 ! sclerotome development +relationship: regulates GO:0061056 ! sclerotome development +created_by: dph +creation_date: 2010-07-14T09:19:47Z + +[Term] +id: GO:0061191 +name: positive regulation of vacuole fusion, non-autophagic +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:dph] +is_a: GO:0032889 ! regulation of vacuole fusion, non-autophagic +is_a: GO:0044090 ! positive regulation of vacuole organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042144 ! vacuole fusion, non-autophagic +relationship: positively_regulates GO:0042144 ! vacuole fusion, non-autophagic +created_by: dph +creation_date: 2010-07-14T09:33:31Z + +[Term] +id: GO:0061192 +name: negative regulation of vacuole fusion, non-autophagic +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:dph] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0032889 ! regulation of vacuole fusion, non-autophagic +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042144 ! vacuole fusion, non-autophagic +relationship: negatively_regulates GO:0042144 ! vacuole fusion, non-autophagic +created_by: dph +creation_date: 2010-07-14T09:35:18Z + +[Term] +id: GO:0061193 +name: taste bud development +namespace: biological_process +def: "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] +is_a: GO:0007423 ! sensory organ development +relationship: part_of GO:0043586 ! tongue development +created_by: dph +creation_date: 2010-07-27T10:55:08Z + +[Term] +id: GO:0061194 +name: taste bud morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] +is_a: GO:0090596 ! sensory organ morphogenesis +relationship: part_of GO:0043587 ! tongue morphogenesis +relationship: part_of GO:0061193 ! taste bud development +created_by: dph +creation_date: 2010-07-27T11:01:31Z + +[Term] +id: GO:0061195 +name: taste bud formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0061194 ! taste bud morphogenesis +created_by: dph +creation_date: 2010-07-27T12:22:26Z + +[Term] +id: GO:0061196 +name: fungiform papilla development +namespace: biological_process +def: "The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043586 ! tongue development +created_by: dph +creation_date: 2010-07-27T12:23:48Z + +[Term] +id: GO:0061197 +name: fungiform papilla morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0043587 ! tongue morphogenesis +relationship: part_of GO:0061196 ! fungiform papilla development +created_by: dph +creation_date: 2010-07-27T12:26:40Z + +[Term] +id: GO:0061198 +name: fungiform papilla formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue." [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0061197 ! fungiform papilla morphogenesis +created_by: dph +creation_date: 2010-07-27T12:29:03Z + +[Term] +id: GO:0061199 +name: striated muscle contraction involved in embryonic body morphogenesis +namespace: biological_process +def: "The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology." [GOC:dph, GOC:kmv] +is_a: GO:0006941 ! striated muscle contraction +intersection_of: GO:0006941 ! striated muscle contraction +intersection_of: part_of GO:0010172 ! embryonic body morphogenesis +relationship: part_of GO:0010172 ! embryonic body morphogenesis +created_by: dph +creation_date: 2010-07-28T04:07:23Z + +[Term] +id: GO:0061200 +name: clathrin-sculpted gamma-aminobutyric acid transport vesicle +namespace: cellular_component +def: "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle." [GOC:dph] +synonym: "clathrin sculpted GABA transport vesicle" EXACT [GOC:dph] +synonym: "clathrin sculpted gamma-aminobutyric acid transport vesicle" EXACT [GOC:sl] +is_a: GO:0060198 ! clathrin-sculpted vesicle +created_by: dph +creation_date: 2010-07-29T10:40:43Z + +[Term] +id: GO:0061201 +name: clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle." [GOC:dph] +synonym: "clathrin sculpted GABA transport vesicle lumen" EXACT [GOC:dph] +synonym: "clathrin sculpted gamma-aminobutyric acid transport vesicle lumen" EXACT [GOC:sl] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0061200 ! clathrin-sculpted gamma-aminobutyric acid transport vesicle +created_by: dph +creation_date: 2010-07-29T10:45:05Z + +[Term] +id: GO:0061202 +name: clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle." [GOC:dph] +synonym: "clathrin sculpted GABA transport vesicle membrane" EXACT [GOC:dph] +synonym: "clathrin sculpted gamma-aminobutyric acid transport vesicle membrane" EXACT [GOC:sl] +is_a: GO:0030665 ! clathrin-coated vesicle membrane +relationship: part_of GO:0061200 ! clathrin-sculpted gamma-aminobutyric acid transport vesicle +created_by: dph +creation_date: 2010-07-29T10:54:33Z + +[Term] +id: GO:0061203 +name: striated muscle paramyosin thick filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle." [GOC:dph, GOC:kmv] +is_a: GO:0061204 ! paramyosin filament assembly or disassembly +relationship: part_of GO:0030239 ! myofibril assembly +created_by: dph +creation_date: 2010-07-29T12:22:31Z + +[Term] +id: GO:0061204 +name: paramyosin filament assembly or disassembly +namespace: biological_process +def: "The formation or disassembly of a filament composed of paramyosin molecules." [GOC:dph, GOC:kmv] +is_a: GO:0030036 ! actin cytoskeleton organization +created_by: dph +creation_date: 2010-07-29T12:26:38Z + +[Term] +id: GO:0061205 +name: paramesonephric duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf] +synonym: "Mullerian duct development" EXACT [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0035295 ! tube development +created_by: dph +creation_date: 2010-07-30T10:54:47Z + +[Term] +id: GO:0061206 +name: mesonephros morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10] +synonym: "Wolffian body morphogenesis" EXACT [GOC:dph] +is_a: GO:0060993 ! kidney morphogenesis +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:11:10Z + +[Term] +id: GO:0061207 +name: mesonephric juxtaglomerulus cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072052 ! juxtaglomerulus cell differentiation +relationship: part_of GO:0061212 ! mesonephric juxtaglomerular apparatus development +created_by: dph +creation_date: 2010-08-19T12:54:08Z + +[Term] +id: GO:0061208 +name: cell differentiation involved in mesonephros development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0001823 ! mesonephros development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:21:23Z + +[Term] +id: GO:0061209 +name: cell proliferation involved in mesonephros development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072111 ! cell proliferation involved in kidney development +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0001823 ! mesonephros development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:22:46Z + +[Term] +id: GO:0061210 +name: cell-cell signaling involved in mesonephros development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] +synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah] +is_a: GO:0060995 ! cell-cell signaling involved in kidney development +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0001823 ! mesonephros development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:24:08Z + +[Term] +id: GO:0061211 +name: mesonephric collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] +is_a: GO:0072044 ! collecting duct development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:25:51Z + +[Term] +id: GO:0061212 +name: mesonephric juxtaglomerular apparatus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate." [GOC:mtg_kidney_jan10] +is_a: GO:0072051 ! juxtaglomerular apparatus development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:27:36Z + +[Term] +id: GO:0061213 +name: positive regulation of mesonephros development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0090184 ! positive regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001823 ! mesonephros development +relationship: positively_regulates GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:39:35Z + +[Term] +id: GO:0061214 +name: mesonephric smooth muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072194 ! kidney smooth muscle tissue development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:29:54Z + +[Term] +id: GO:0061215 +name: mesonephric nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0072006 ! nephron development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:31:08Z + +[Term] +id: GO:0061216 +name: regulation of transcription from RNA polymerase II promoter involved in mesonephros development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0060994 ! regulation of transcription from RNA polymerase II promoter involved in kidney development +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0001823 ! mesonephros development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:32:27Z + +[Term] +id: GO:0061217 +name: regulation of mesonephros development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001823 ! mesonephros development +relationship: regulates GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:35:31Z + +[Term] +id: GO:0061218 +name: negative regulation of mesonephros development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0090185 ! negative regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001823 ! mesonephros development +relationship: negatively_regulates GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:43:06Z + +[Term] +id: GO:0061219 +name: mesonephric mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072074 ! kidney mesenchyme development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-17T03:45:44Z + +[Term] +id: GO:0061220 +name: mesonephric macula densa development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0061241 ! mesonephric nephron epithelium development +is_a: GO:0072024 ! macula densa development +relationship: part_of GO:0061212 ! mesonephric juxtaglomerular apparatus development +created_by: dph +creation_date: 2010-08-19T01:11:41Z + +[Term] +id: GO:0061221 +name: mesonephric mesenchyme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072131 ! kidney mesenchyme morphogenesis +relationship: part_of GO:0061219 ! mesonephric mesenchyme development +created_by: dph +creation_date: 2010-08-19T01:17:38Z + +[Term] +id: GO:0061222 +name: mesonephric mesenchymal cell proliferation involved in mesonephros development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population." [GOC:mtg_kidney_jan10] +is_a: GO:0061209 ! cell proliferation involved in mesonephros development +is_a: GO:0072135 ! kidney mesenchymal cell proliferation +relationship: part_of GO:0061219 ! mesonephric mesenchyme development +created_by: dph +creation_date: 2010-08-19T01:20:14Z + +[Term] +id: GO:0061223 +name: mesonephric mesenchymal cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072161 ! mesenchymal cell differentiation involved in kidney development +relationship: part_of GO:0061219 ! mesonephric mesenchyme development +created_by: dph +creation_date: 2010-08-19T01:21:48Z + +[Term] +id: GO:0061224 +name: mesonephric glomerulus development +namespace: biological_process +def: "The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0032835 ! glomerulus development +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-08-19T01:26:00Z + +[Term] +id: GO:0061225 +name: mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development +namespace: biological_process +def: "The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10] +synonym: "mesonephric Goormaghtigh proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "mesonephric lacis cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0061209 ! cell proliferation involved in mesonephros development +is_a: GO:0072122 ! extraglomerular mesangial cell proliferation +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-08-19T01:34:59Z + +[Term] +id: GO:0061226 +name: proximal/distal pattern formation involved in mesonephric nephron development +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end)." [GOC:mtg_kidney_jan10] +is_a: GO:0061227 ! pattern specification involved in mesonephros development +is_a: GO:0072047 ! proximal/distal pattern formation involved in nephron development +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-08-19T02:10:25Z + +[Term] +id: GO:0061227 +name: pattern specification involved in mesonephros development +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] +synonym: "mesonephros pattern formation" RELATED [GOC:mtg_kidney_jan10] +synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061004 ! pattern specification involved in kidney development +intersection_of: GO:0007389 ! pattern specification process +intersection_of: part_of GO:0001823 ! mesonephros development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-08-19T02:22:22Z + +[Term] +id: GO:0061228 +name: mesonephric nephron morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0061206 ! mesonephros morphogenesis +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-08-19T02:26:24Z + +[Term] +id: GO:0061229 +name: mesonephric juxtaglomerulus cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072142 ! juxtaglomerulus cell development +relationship: part_of GO:0061207 ! mesonephric juxtaglomerulus cell differentiation +created_by: dph +creation_date: 2010-08-19T02:34:25Z + +[Term] +id: GO:0061230 +name: mesonephric juxtaglomerulus cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell." [GOC:mtg_kidney_jan10] +is_a: GO:0072150 ! juxtaglomerulus cell fate commitment +relationship: part_of GO:0061207 ! mesonephric juxtaglomerulus cell differentiation +created_by: dph +creation_date: 2010-08-19T02:36:23Z + +[Term] +id: GO:0061231 +name: mesonephric glomerulus vasculature development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072012 ! glomerulus vasculature development +relationship: part_of GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-08-19T02:47:06Z + +[Term] +id: GO:0061232 +name: mesonephric glomerular epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0061241 ! mesonephric nephron epithelium development +is_a: GO:0072010 ! glomerular epithelium development +relationship: part_of GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-08-19T02:49:46Z + +[Term] +id: GO:0061233 +name: mesonephric glomerular basement membrane development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration." [GOC:mtg_kidney_jan10] +is_a: GO:0032836 ! glomerular basement membrane development +relationship: part_of GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-08-19T02:52:18Z + +[Term] +id: GO:0061234 +name: mesonephric glomerulus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072102 ! glomerulus morphogenesis +relationship: part_of GO:0061224 ! mesonephric glomerulus development +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T02:53:35Z + +[Term] +id: GO:0061235 +name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T02:57:11Z + +[Term] +id: GO:0061236 +name: mesonephric comma-shaped body morphogenesis +namespace: biological_process +def: "The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072049 ! comma-shaped body morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:00:21Z + +[Term] +id: GO:0061237 +name: convergent extension involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072045 ! convergent extension involved in nephron morphogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:02:44Z + +[Term] +id: GO:0061238 +name: establishment of planar polarity involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "establishment of planar cell polarity involved in mesonephric nephron morphogenesis" NARROW [GOC:mtg_kidney_jan10] +is_a: GO:0072046 ! establishment of planar polarity involved in nephron morphogenesis +intersection_of: GO:0001736 ! establishment of planar polarity +intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:04:40Z + +[Term] +id: GO:0061239 +name: mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072037 ! mesenchymal stem cell differentiation involved in nephron morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:06:46Z + +[Term] +id: GO:0061240 +name: mesonephric nephron tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072171 ! mesonephric tubule morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +relationship: part_of GO:0061242 ! mesonephric nephron tubule development +created_by: dph +creation_date: 2010-08-19T03:09:26Z + +[Term] +id: GO:0061241 +name: mesonephric nephron epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +is_a: GO:0072163 ! mesonephric epithelium development +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-08-19T03:11:59Z + +[Term] +id: GO:0061242 +name: mesonephric nephron tubule development +namespace: biological_process +def: "The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0061241 ! mesonephric nephron epithelium development +is_a: GO:0072080 ! nephron tubule development +is_a: GO:0072164 ! mesonephric tubule development +created_by: dph +creation_date: 2010-08-19T03:17:00Z + +[Term] +id: GO:0061243 +name: mesonephric renal vesicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072077 ! renal vesicle morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:20:21Z + +[Term] +id: GO:0061244 +name: mesonephric S-shaped body morphogenesis +namespace: biological_process +def: "The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072050 ! S-shaped body morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-08-19T03:23:55Z + +[Term] +id: GO:0061245 +name: establishment or maintenance of bipolar cell polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns." [GOC:dph, GOC:vw] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +created_by: dph +creation_date: 2010-08-23T09:42:05Z + +[Term] +id: GO:0061246 +name: establishment or maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell." [GOC:dph, GOC:vw] +is_a: GO:0061245 ! establishment or maintenance of bipolar cell polarity +is_a: GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: dph +creation_date: 2010-08-23T09:46:01Z + +[Term] +id: GO:0061247 +name: mesonephric glomerular mesangium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072109 ! glomerular mesangium development +relationship: part_of GO:0061231 ! mesonephric glomerulus vasculature development +created_by: dph +creation_date: 2010-08-30T12:59:25Z + +[Term] +id: GO:0061248 +name: mesonephric glomerulus vasculature morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072103 ! glomerulus vasculature morphogenesis +relationship: part_of GO:0061231 ! mesonephric glomerulus vasculature development +relationship: part_of GO:0061234 ! mesonephric glomerulus morphogenesis +created_by: dph +creation_date: 2010-08-30T01:11:34Z + +[Term] +id: GO:0061249 +name: mesonephric glomerular capillary formation +namespace: biological_process +def: "The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts." [GOC:mtg_kidney_jan10] +is_a: GO:0072104 ! glomerular capillary formation +relationship: part_of GO:0061248 ! mesonephric glomerulus vasculature morphogenesis +created_by: dph +creation_date: 2010-08-30T01:17:08Z + +[Term] +id: GO:0061250 +name: mesonephric glomerular epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072311 ! glomerular epithelial cell differentiation +relationship: part_of GO:0061232 ! mesonephric glomerular epithelium development +created_by: dph +creation_date: 2010-08-30T01:20:03Z + +[Term] +id: GO:0061251 +name: mesonephric glomerular epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072310 ! glomerular epithelial cell development +relationship: part_of GO:0061250 ! mesonephric glomerular epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T01:20:45Z + +[Term] +id: GO:0061252 +name: mesonephric glomerular epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072314 ! glomerular epithelial cell fate commitment +relationship: part_of GO:0061250 ! mesonephric glomerular epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T01:23:50Z + +[Term] +id: GO:0061253 +name: mesonephric glomerular parietal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +is_a: GO:0061250 ! mesonephric glomerular epithelial cell differentiation +is_a: GO:0072139 ! glomerular parietal epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T01:26:47Z + +[Term] +id: GO:0061254 +name: mesonephric glomerular parietal epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +is_a: GO:0061251 ! mesonephric glomerular epithelial cell development +is_a: GO:0072016 ! glomerular parietal epithelial cell development +relationship: part_of GO:0061253 ! mesonephric glomerular parietal epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T01:30:36Z + +[Term] +id: GO:0061255 +name: mesonephric glomerular parietal epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes." [GOC:mtg_kidney_jan10] +is_a: GO:0061252 ! mesonephric glomerular epithelial cell fate commitment +is_a: GO:0072147 ! glomerular parietal epithelial cell fate commitment +relationship: part_of GO:0061253 ! mesonephric glomerular parietal epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T01:33:52Z + +[Term] +id: GO:0061256 +name: mesonephric glomerular visceral epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0061250 ! mesonephric glomerular epithelial cell differentiation +is_a: GO:0072112 ! glomerular visceral epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:03:38Z + +[Term] +id: GO:0061257 +name: mesonephric glomerular visceral epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0061251 ! mesonephric glomerular epithelial cell development +is_a: GO:0072015 ! glomerular visceral epithelial cell development +relationship: part_of GO:0061256 ! mesonephric glomerular visceral epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:10:40Z + +[Term] +id: GO:0061258 +name: mesonephric glomerular visceral epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0061251 ! mesonephric glomerular epithelial cell development +is_a: GO:0072149 ! glomerular visceral epithelial cell fate commitment +relationship: part_of GO:0061256 ! mesonephric glomerular visceral epithelial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:13:33Z + +[Term] +id: GO:0061259 +name: mesonephric glomerular mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061260 ! mesonephric mesangial cell differentiation +is_a: GO:0072008 ! glomerular mesangial cell differentiation +relationship: part_of GO:0061247 ! mesonephric glomerular mesangium development +created_by: dph +creation_date: 2010-08-30T02:22:45Z + +[Term] +id: GO:0061260 +name: mesonephric mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072007 ! mesangial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:25:08Z + +[Term] +id: GO:0061261 +name: mesenchymal to epithelial transition involved in mesonephros morphogenesis +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "mesonephric mesenchyme to epithelial transition" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +is_a: GO:0060231 ! mesenchymal to epithelial transition +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +intersection_of: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: part_of GO:0061206 ! mesonephros morphogenesis +relationship: part_of GO:0061206 ! mesonephros morphogenesis +created_by: dph +creation_date: 2010-08-30T02:35:15Z + +[Term] +id: GO:0061262 +name: mesonephric renal vesicle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072033 ! renal vesicle formation +relationship: part_of GO:0061243 ! mesonephric renal vesicle morphogenesis +created_by: dph +creation_date: 2010-08-30T02:41:20Z + +[Term] +id: GO:0061263 +name: mesonephric glomerular mesangial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072144 ! glomerular mesangial cell development +relationship: part_of GO:0061259 ! mesonephric glomerular mesangial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:52:55Z + +[Term] +id: GO:0061264 +name: mesonephric glomerular mesangial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell." [GOC:mtg_kidney_jan10] +is_a: GO:0072152 ! glomerular mesangial cell fate commitment +relationship: part_of GO:0061259 ! mesonephric glomerular mesangial cell differentiation +created_by: dph +creation_date: 2010-08-30T02:59:11Z + +[Term] +id: GO:0061265 +name: mesonephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072160 ! nephron tubule epithelial cell differentiation +relationship: part_of GO:0061242 ! mesonephric nephron tubule development +created_by: dph +creation_date: 2010-08-30T03:02:09Z + +[Term] +id: GO:0061266 +name: mesonephric interstitial fibroblast differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "mesonephros interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072071 ! kidney interstitial fibroblast differentiation +created_by: dph +creation_date: 2010-08-30T03:12:17Z + +[Term] +id: GO:0061267 +name: mesonephric interstitial fibroblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +synonym: "mesonephros interstitial cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072141 ! renal interstitial fibroblast development +relationship: part_of GO:0061266 ! mesonephric interstitial fibroblast differentiation +created_by: dph +creation_date: 2010-08-30T03:14:31Z + +[Term] +id: GO:0061268 +name: mesonephric interstitial fibroblast fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast." [GOC:mtg_kidney_jan10] +is_a: GO:0072153 ! renal interstitial fibroblast fate commitment +relationship: part_of GO:0061266 ! mesonephric interstitial fibroblast differentiation +created_by: dph +creation_date: 2010-08-30T03:16:52Z + +[Term] +id: GO:0061269 +name: mesonephric glomerular mesangial cell proliferation involved in mesonephros development +namespace: biological_process +def: "The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population." [GOC:mtg_kidney_jan10] +is_a: GO:0061209 ! cell proliferation involved in mesonephros development +is_a: GO:0072110 ! glomerular mesangial cell proliferation +relationship: part_of GO:0061247 ! mesonephric glomerular mesangium development +created_by: dph +creation_date: 2010-08-30T03:20:57Z + +[Term] +id: GO:0061270 +name: mesonephric intraglomerular mesangial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis." [GOC:mtg_kidney_jan10] +is_a: GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +is_a: GO:0072123 ! intraglomerular mesangial cell proliferation +created_by: dph +creation_date: 2010-08-30T03:23:10Z + +[Term] +id: GO:0061271 +name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] +is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation +intersection_of: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation +relationship: part_of GO:0061262 ! mesonephric renal vesicle formation +created_by: dph +creation_date: 2010-08-30T03:26:30Z + +[Term] +id: GO:0061272 +name: mesonephric connecting tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "mesonephric collecting tubule development" EXACT [GOC:dph] +synonym: "mesonephric connecting duct development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0061242 ! mesonephric nephron tubule development +is_a: GO:0072027 ! connecting tubule development +created_by: dph +creation_date: 2010-09-02T12:00:56Z + +[Term] +id: GO:0061273 +name: mesonephric distal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0061240 ! mesonephric nephron tubule morphogenesis +is_a: GO:0072156 ! distal tubule morphogenesis +relationship: part_of GO:0061274 ! mesonephric distal tubule development +created_by: dph +creation_date: 2010-09-02T12:12:00Z + +[Term] +id: GO:0061274 +name: mesonephric distal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0061242 ! mesonephric nephron tubule development +is_a: GO:0072017 ! distal tubule development +created_by: dph +creation_date: 2010-09-02T12:16:25Z + +[Term] +id: GO:0061275 +name: mesonephric proximal tubule development +namespace: biological_process +def: "The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0061242 ! mesonephric nephron tubule development +is_a: GO:0072014 ! proximal tubule development +created_by: dph +creation_date: 2010-09-02T01:08:05Z + +[Term] +id: GO:0061276 +name: mesonephric proximal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0061240 ! mesonephric nephron tubule morphogenesis +is_a: GO:0072158 ! proximal tubule morphogenesis +relationship: part_of GO:0061275 ! mesonephric proximal tubule development +created_by: dph +creation_date: 2010-09-02T01:11:02Z + +[Term] +id: GO:0061277 +name: mesonephric nephron tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072172 ! mesonephric tubule formation +relationship: part_of GO:0061240 ! mesonephric nephron tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:16:21Z + +[Term] +id: GO:0061278 +name: epithelial cell migration involved in mesonephric nephron tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0061240 ! mesonephric nephron tubule morphogenesis +relationship: part_of GO:0061240 ! mesonephric nephron tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:18:53Z + +[Term] +id: GO:0061279 +name: epithelial cell migration involved in mesonephric distal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0061278 ! epithelial cell migration involved in mesonephric nephron tubule morphogenesis +is_a: GO:0072157 ! epithelial cell migration involved in distal tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0061273 ! mesonephric distal tubule morphogenesis +relationship: part_of GO:0061273 ! mesonephric distal tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:20:56Z + +[Term] +id: GO:0061280 +name: epithelial cell migration involved in mesonephric proximal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0061278 ! epithelial cell migration involved in mesonephric nephron tubule morphogenesis +is_a: GO:0072159 ! epithelial cell migration involved in proximal tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0061276 ! mesonephric proximal tubule morphogenesis +relationship: part_of GO:0061276 ! mesonephric proximal tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:23:43Z + +[Term] +id: GO:0061281 +name: specification of mesonephric connecting tubule identity +namespace: biological_process +def: "The process in which the connecting tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10] +synonym: "specification of mesonephric collecting tubule identity" EXACT [GOC:dph] +is_a: GO:0061282 ! specification of mesonephric nephron tubule identity +is_a: GO:0072085 ! specification of connecting tubule identity +relationship: part_of GO:0061272 ! mesonephric connecting tubule development +created_by: dph +creation_date: 2010-09-02T01:26:09Z + +[Term] +id: GO:0061282 +name: specification of mesonephric nephron tubule identity +namespace: biological_process +def: "The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity." [GOC:mtg_kidney_jan10] +is_a: GO:0061227 ! pattern specification involved in mesonephros development +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0061226 ! proximal/distal pattern formation involved in mesonephric nephron development +relationship: part_of GO:0061277 ! mesonephric nephron tubule formation +created_by: dph +creation_date: 2010-09-02T01:37:44Z + +[Term] +id: GO:0061283 +name: specification of mesonephric distal tubule identity +namespace: biological_process +def: "The process in which the distal tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10] +is_a: GO:0061282 ! specification of mesonephric nephron tubule identity +is_a: GO:0072084 ! specification of distal tubule identity +relationship: part_of GO:0061273 ! mesonephric distal tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:42:10Z + +[Term] +id: GO:0061284 +name: specification of mesonephric proximal tubule identity +namespace: biological_process +def: "The process in which the proximal tubule of the mesonephric nephron acquires its identity." [GOC:mtg_kidney_jan10] +is_a: GO:0061282 ! specification of mesonephric nephron tubule identity +is_a: GO:0072082 ! specification of proximal tubule identity +relationship: part_of GO:0061276 ! mesonephric proximal tubule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:44:24Z + +[Term] +id: GO:0061285 +name: mesonephric capsule development +namespace: biological_process +def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10] +is_a: GO:0072127 ! renal capsule development +relationship: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-09-02T01:50:06Z + +[Term] +id: GO:0061286 +name: mesonephric capsule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] +is_a: GO:0072128 ! renal capsule morphogenesis +relationship: part_of GO:0061285 ! mesonephric capsule development +created_by: dph +creation_date: 2010-09-02T01:53:31Z + +[Term] +id: GO:0061287 +name: mesonephric capsule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] +is_a: GO:0072129 ! renal capsule formation +relationship: part_of GO:0061286 ! mesonephric capsule morphogenesis +created_by: dph +creation_date: 2010-09-02T01:55:03Z + +[Term] +id: GO:0061288 +name: mesonephric capsule specification +namespace: biological_process +def: "The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:mtg_kidney_jan10] +is_a: GO:0061227 ! pattern specification involved in mesonephros development +is_a: GO:0072130 ! renal capsule specification +relationship: part_of GO:0061287 ! mesonephric capsule formation +created_by: dph +creation_date: 2010-09-02T01:56:20Z + +[Term] +id: GO:0061289 +name: Wnt signaling pathway involved in kidney development +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time." [GOC:mtg_kidney_jan10] +synonym: "Wnt receptor signaling pathway involved in kidney development" EXACT [] +synonym: "Wnt receptor signalling pathway involved in kidney development" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in kidney development" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +is_a: GO:0060995 ! cell-cell signaling involved in kidney development +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2010-09-03T12:04:50Z + +[Term] +id: GO:0061290 +name: canonical Wnt signaling pathway involved in metanephric kidney development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10] +synonym: "canonical Wnt receptor signaling pathway involved in metanephric kidney development" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in metanephric kidney development" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in metanephric kidney development" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +is_a: GO:0061289 ! Wnt signaling pathway involved in kidney development +is_a: GO:0072204 ! cell-cell signaling involved in metanephros development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0001656 ! metanephros development +created_by: dph +creation_date: 2010-09-03T12:06:10Z + +[Term] +id: GO:0061291 +name: canonical Wnt signaling pathway involved in ureteric bud branching +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10] +synonym: "canonical Wnt receptor signaling pathway involved in ureteric bud branching" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in ureteric bud branching" EXACT [GOC:mah] +is_a: GO:0061290 ! canonical Wnt signaling pathway involved in metanephric kidney development +is_a: GO:0061292 ! canonical Wnt signaling pathway involved in mesonephros development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: part_of GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: dph +creation_date: 2010-09-03T12:15:19Z + +[Term] +id: GO:0061292 +name: canonical Wnt signaling pathway involved in mesonephros development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10] +synonym: "canonical Wnt receptor signaling pathway involved in mesonephros development" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in mesonephros development" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in mesonephros development" EXACT [GOC:signaling] +is_a: GO:0060070 ! canonical Wnt signaling pathway +is_a: GO:0061210 ! cell-cell signaling involved in mesonephros development +is_a: GO:0061289 ! Wnt signaling pathway involved in kidney development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0001823 ! mesonephros development +created_by: dph +creation_date: 2010-09-03T12:23:09Z + +[Term] +id: GO:0061293 +name: canonical Wnt signaling pathway involved in mesonephric nephron development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_kidney_jan10] +synonym: "canonical Wnt receptor signaling pathway involved in mesonephric nephron development" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in mesonephric nephron development" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in mesonephric nephron development" EXACT [GOC:signaling] +is_a: GO:0061292 ! canonical Wnt signaling pathway involved in mesonephros development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0061215 ! mesonephric nephron development +relationship: part_of GO:0061215 ! mesonephric nephron development +created_by: dph +creation_date: 2010-09-03T12:49:43Z + +[Term] +id: GO:0061294 +name: mesonephric renal vesicle induction +namespace: biological_process +def: "Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0072034 ! renal vesicle induction +relationship: positively_regulates GO:0061262 ! mesonephric renal vesicle formation +created_by: dph +creation_date: 2010-09-03T12:57:59Z + +[Term] +id: GO:0061295 +name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] +synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +relationship: regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis +relationship: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-09-06T09:48:56Z + +[Term] +id: GO:0061296 +name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] +synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +relationship: negatively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis +relationship: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-09-06T09:54:49Z + +[Term] +id: GO:0061297 +name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] +synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +relationship: positively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis +relationship: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +created_by: dph +creation_date: 2010-09-06T09:58:59Z + +[Term] +id: GO:0061298 +name: retina vasculature development in camera-type eye +namespace: biological_process +def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] +synonym: "retinal vasculature development" EXACT [GOC:dph] +is_a: GO:0001944 ! vasculature development +relationship: part_of GO:0060041 ! retina development in camera-type eye +created_by: dph +creation_date: 2010-09-06T03:27:06Z + +[Term] +id: GO:0061299 +name: retina vasculature morphogenesis in camera-type eye +namespace: biological_process +def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph] +synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0061298 ! retina vasculature development in camera-type eye +created_by: dph +creation_date: 2010-09-06T03:28:25Z + +[Term] +id: GO:0061300 +name: cerebellum vasculature development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0001944 ! vasculature development +created_by: dph +creation_date: 2010-09-06T03:36:40Z + +[Term] +id: GO:0061301 +name: cerebellum vasculature morphogenesis +namespace: biological_process +def: "The process in which the vasculature of the cerebellum is generated and organized." [GOC:BHF, GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0021549 ! cerebellum development +relationship: part_of GO:0061300 ! cerebellum vasculature development +created_by: dph +creation_date: 2010-09-06T03:38:05Z + +[Term] +id: GO:0061302 +name: smooth muscle cell-matrix adhesion +namespace: biological_process +def: "The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules." [GOC:BHF, GOC:dph, PMID:8837777] +is_a: GO:0007160 ! cell-matrix adhesion +property_value: RO:0002161 NCBITaxon:4751 +created_by: dph +creation_date: 2010-09-14T11:08:00Z + +[Term] +id: GO:0061303 +name: cornea development in camera-type eye +namespace: biological_process +def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0043010 ! camera-type eye development +created_by: dph +creation_date: 2010-09-14T02:09:08Z + +[Term] +id: GO:0061304 +name: retinal blood vessel morphogenesis +namespace: biological_process +def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] +is_a: GO:0048514 ! blood vessel morphogenesis +is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye +created_by: dph +creation_date: 2010-09-16T09:02:59Z + +[Term] +id: GO:0061305 +name: maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell." [GOC:dph, GOC:vw] +is_a: GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-09-16T09:25:18Z + +[Term] +id: GO:0061306 +name: DNA strand renaturation involved in double-strand break repair +namespace: biological_process +def: "The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair." [GOC:dph] +is_a: GO:0000733 ! DNA strand renaturation +intersection_of: GO:0000733 ! DNA strand renaturation +intersection_of: part_of GO:0006302 ! double-strand break repair +relationship: part_of GO:0045002 ! double-strand break repair via single-strand annealing +created_by: dph +creation_date: 2010-09-21T09:36:47Z + +[Term] +id: GO:0061307 +name: cardiac neural crest cell differentiation involved in heart development +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442] +is_a: GO:0014033 ! neural crest cell differentiation +is_a: GO:0035051 ! cardiocyte differentiation +intersection_of: GO:0014033 ! neural crest cell differentiation +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-23T08:50:56Z + +[Term] +id: GO:0061308 +name: cardiac neural crest cell development involved in heart development +namespace: biological_process +def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart] +is_a: GO:0014032 ! neural crest cell development +intersection_of: GO:0014032 ! neural crest cell development +intersection_of: part_of GO:0007507 ! heart development +relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development +created_by: dph +creation_date: 2010-09-23T09:01:49Z + +[Term] +id: GO:0061309 +name: cardiac neural crest cell development involved in outflow tract morphogenesis +namespace: biological_process +def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] +is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development +intersection_of: GO:0014032 ! neural crest cell development +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: dph +creation_date: 2010-09-23T09:08:37Z + +[Term] +id: GO:0061310 +name: canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation." [GOC:dph, GOC:mtg_heart] +synonym: "canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development" EXACT [GOC:signaling] +is_a: GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development +relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development +created_by: dph +creation_date: 2010-09-23T09:12:36Z + +[Term] +id: GO:0061311 +name: cell surface receptor signaling pathway involved in heart development +namespace: biological_process +def: "Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time." [GOC:dph, GOC:mtg_heart, GOC:signaling] +synonym: "cell surface receptor linked signaling pathway involved in heart development" EXACT [GOC:bf] +synonym: "cell surface receptor linked signalling pathway involved in heart development" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: part_of GO:0007507 ! heart development +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-23T09:18:32Z + +[Term] +id: GO:0061312 +name: BMP signaling pathway involved in heart development +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time." [GOC:dph, GOC:mtg_heart] +synonym: "BMP signalling pathway involved in heart development" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-23T11:02:14Z + +[Term] +id: GO:0061313 +name: fibroblast growth factor receptor signaling pathway involved in heart development +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time." [GOC:mtg_heart] +synonym: "fibroblast growth factor receptor signalling pathway involved in heart development" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-24T08:15:08Z + +[Term] +id: GO:0061314 +name: Notch signaling involved in heart development +namespace: biological_process +def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time." [GOC:mtg_heart] +synonym: "Notch signalling involved in heart development" EXACT [GOC:mah] +is_a: GO:0007219 ! Notch signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-24T08:25:22Z + +[Term] +id: GO:0061315 +name: canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation +namespace: biological_process +def: "The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells." [GOC:mtg_heart] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation" EXACT [GOC:signaling] +is_a: GO:0044340 ! canonical Wnt signaling pathway involved in regulation of cell proliferation +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: part_of GO:0060045 ! positive regulation of cardiac muscle cell proliferation +relationship: part_of GO:0060045 ! positive regulation of cardiac muscle cell proliferation +created_by: dph +creation_date: 2010-09-24T08:53:58Z + +[Term] +id: GO:0061316 +name: canonical Wnt signaling pathway involved in heart development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_heart] +synonym: "canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:signaling] +is_a: GO:0003306 ! Wnt signaling pathway involved in heart development +is_a: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-24T09:25:03Z + +[Term] +id: GO:0061317 +name: canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:mtg_heart, PMID:17576928] +synonym: "canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:signaling] +synonym: "canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:signaling] +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0060923 ! cardiac muscle cell fate commitment +relationship: part_of GO:0060923 ! cardiac muscle cell fate commitment +created_by: dph +creation_date: 2010-09-24T09:29:21Z + +[Term] +id: GO:0061318 +name: renal filtration cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0072001 ! renal system development +created_by: dph +creation_date: 2010-09-24T12:18:35Z + +[Term] +id: GO:0061319 +name: nephrocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0002520, GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0061318 ! renal filtration cell differentiation +created_by: dph +creation_date: 2010-09-24T12:23:29Z + +[Term] +id: GO:0061320 +name: pericardial nephrocyte differentiation +namespace: biological_process +alt_id: GO:0007513 +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0000474, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135] +synonym: "pericardial cell differentiation" NARROW [] +is_a: GO:0061319 ! nephrocyte differentiation +created_by: dph +creation_date: 2010-09-24T12:25:53Z + +[Term] +id: GO:0061321 +name: garland nephrocyte differentiation +namespace: biological_process +alt_id: GO:0007514 +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0000486, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135] +synonym: "garland cell differentiation" EXACT [] +is_a: GO:0061319 ! nephrocyte differentiation +relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm +created_by: dph +creation_date: 2010-09-24T12:28:16Z + +[Term] +id: GO:0061322 +name: disseminated nephrocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0002524, GOC:19783135, GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0061319 ! nephrocyte differentiation +created_by: dph +creation_date: 2010-09-24T12:30:46Z + +[Term] +id: GO:0061323 +name: cell proliferation involved in heart morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart] +is_a: GO:0008283 ! cell population proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2010-09-28T09:05:26Z + +[Term] +id: GO:0061324 +name: canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation +namespace: biological_process +def: "The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells." [GOC:dph, GOC:mtg_heart] +synonym: "canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation" EXACT [] +synonym: "canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation" EXACT [GOC:mah] +synonym: "canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation" EXACT [GOC:signaling] +is_a: GO:0044340 ! canonical Wnt signaling pathway involved in regulation of cell proliferation +is_a: GO:0061316 ! canonical Wnt signaling pathway involved in heart development +is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis +created_by: dph +creation_date: 2010-09-28T09:19:37Z + +[Term] +id: GO:0061325 +name: cell proliferation involved in outflow tract morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: dph +creation_date: 2010-09-28T09:29:30Z + +[Term] +id: GO:0061326 +name: renal tubule development +namespace: biological_process +def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0072001 ! renal system development +created_by: dph +creation_date: 2010-09-28T12:50:43Z + +[Term] +id: GO:0061327 +name: anterior Malpighian tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0072002 ! Malpighian tubule development +created_by: dph +creation_date: 2010-09-28T01:23:18Z + +[Term] +id: GO:0061328 +name: posterior Malpighian tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0072002 ! Malpighian tubule development +created_by: dph +creation_date: 2010-09-28T01:24:35Z + +[Term] +id: GO:0061329 +name: Malpighian tubule principal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0072002 ! Malpighian tubule development +created_by: dph +creation_date: 2010-09-28T01:26:33Z + +[Term] +id: GO:0061330 +name: Malpighian tubule stellate cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0072002 ! Malpighian tubule development +created_by: dph +creation_date: 2010-09-28T01:32:55Z + +[Term] +id: GO:0061331 +name: epithelial cell proliferation involved in Malpighian tubule morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:2001013 ! epithelial cell proliferation involved in renal tubule morphogenesis +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-09-28T02:01:02Z + +[Term] +id: GO:0061332 +name: Malpighian tubule bud morphogenesis +namespace: biological_process +def: "The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +synonym: "Malpighian tubule formation" EXACT [GOC:dph] +is_a: GO:0060572 ! morphogenesis of an epithelial bud +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-09-28T01:39:32Z + +[Term] +id: GO:0061333 +name: renal tubule morphogenesis +namespace: biological_process +def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0061326 ! renal tubule development +created_by: dph +creation_date: 2010-09-28T01:43:04Z + +[Term] +id: GO:0061334 +name: cell rearrangement involved in Malpighian tubule morphogenesis +namespace: biological_process +def: "The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10] +synonym: "cell migration involved in Malpighian tubule morphogenesis" EXACT [] +is_a: GO:0016477 ! cell migration +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-09-28T02:04:05Z + +[Term] +id: GO:0061335 +name: cell growth involved in Malpighian tubule morphogenesis +namespace: biological_process +def: "The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0048588 ! developmental cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +intersection_of: GO:0048588 ! developmental cell growth +intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-09-28T02:08:25Z + +[Term] +id: GO:0061336 +name: cell morphogenesis involved in Malpighian tubule morphogenesis +namespace: biological_process +def: "The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: GO:0000904 ! cell morphogenesis involved in differentiation +intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis +relationship: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-09-28T02:11:47Z + +[Term] +id: GO:0061337 +name: cardiac conduction +namespace: biological_process +def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:0035637 ! multicellular organismal signaling +created_by: dph +creation_date: 2010-09-29T08:46:05Z + +[Term] +id: GO:0061338 +name: obsolete atrioventricular node impulse conduction delay +namespace: biological_process +def: "OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract." [GOC:dph] +comment: This term was made obsolete because it was created before the cardiac conduction overhaul, and represents a measurement rather than a process. +synonym: "atrioventricular node impulse conduction delay" EXACT [] +is_obsolete: true +consider: GO:0086016 +created_by: dph +creation_date: 2010-09-29T08:55:53Z + +[Term] +id: GO:0061339 +name: establishment or maintenance of monopolar cell polarity +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis." [GOC:dph, GOC:vw] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +created_by: dph +creation_date: 2010-09-29T09:10:05Z + +[Term] +id: GO:0061340 +name: establishment or maintenance of monopolar cell polarity regulating cell shape +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell." [GOC:dph, GOC:vw] +is_a: GO:0061339 ! establishment or maintenance of monopolar cell polarity +is_a: GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: dph +creation_date: 2010-09-29T09:13:55Z + +[Term] +id: GO:0061341 +name: non-canonical Wnt signaling pathway involved in heart development +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time." [GOC:dph, GOC:mtg_heart, PMID:16860783] +synonym: "non-canonical Wnt receptor signaling pathway involved in heart development" EXACT [] +synonym: "non-canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:mah] +synonym: "non-canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:signaling] +is_a: GO:0003306 ! Wnt signaling pathway involved in heart development +is_a: GO:0035567 ! non-canonical Wnt signaling pathway +intersection_of: GO:0035567 ! non-canonical Wnt signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-09-29T11:27:34Z + +[Term] +id: GO:0061342 +name: regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart." [PMID:16860783] +synonym: "regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway" EXACT [GOC:mah] +is_a: GO:0061341 ! non-canonical Wnt signaling pathway involved in heart development +is_a: GO:0061344 ! regulation of cell adhesion involved in heart morphogenesis +created_by: dph +creation_date: 2010-09-29T11:30:15Z + +[Term] +id: GO:0061343 +name: cell adhesion involved in heart morphogenesis +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] +is_a: GO:0007155 ! cell adhesion +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0003007 ! heart morphogenesis +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2010-09-29T11:34:06Z + +[Term] +id: GO:0061344 +name: regulation of cell adhesion involved in heart morphogenesis +namespace: biological_process +def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] +is_a: GO:0030155 ! regulation of cell adhesion +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis +relationship: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis +created_by: dph +creation_date: 2010-09-29T11:35:27Z + +[Term] +id: GO:0061345 +name: planar cell polarity pathway involved in cardiac muscle cell fate commitment +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate." [GOC:dph, GOC:mtg_heart, PMID:16860783] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +is_a: GO:0061341 ! non-canonical Wnt signaling pathway involved in heart development +created_by: dph +creation_date: 2010-09-30T12:39:05Z + +[Term] +id: GO:0061346 +name: planar cell polarity pathway involved in heart morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +is_a: GO:0061341 ! non-canonical Wnt signaling pathway involved in heart development +relationship: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2010-09-30T12:47:24Z + +[Term] +id: GO:0061347 +name: planar cell polarity pathway involved in outflow tract morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart, PMID:19056682] +is_a: GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: dph +creation_date: 2010-10-01T10:38:56Z + +[Term] +id: GO:0061348 +name: planar cell polarity pathway involved in ventricular septum morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum." [GOC:dph, GOC:mtg_heart, PMID:19056682] +is_a: GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: part_of GO:0060412 ! ventricular septum morphogenesis +created_by: dph +creation_date: 2010-10-01T10:47:49Z + +[Term] +id: GO:0061349 +name: planar cell polarity pathway involved in cardiac right atrium morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium." [GOC:dph, GOC:mtg_heart, PMID:19056682] +is_a: GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis +created_by: dph +creation_date: 2010-10-01T10:52:01Z + +[Term] +id: GO:0061350 +name: planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue." [GOC:dph, GOC:mtg_heart, PMID:19056682] +is_a: GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis +created_by: dph +creation_date: 2010-10-01T10:57:33Z + +[Term] +id: GO:0061351 +name: neural precursor cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf] +is_a: GO:0008283 ! cell population proliferation +created_by: dph +creation_date: 2010-10-01T11:06:04Z + +[Term] +id: GO:0061352 +name: cell chemotaxis involved in Malpighian tubule morphogenesis +namespace: biological_process +def: "The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0060326 ! cell chemotaxis +is_a: GO:0061334 ! cell rearrangement involved in Malpighian tubule morphogenesis +intersection_of: GO:0060326 ! cell chemotaxis +intersection_of: part_of GO:0007443 ! Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-10-01T11:57:28Z + +[Term] +id: GO:0061353 +name: BMP signaling pathway involved in Malpighian tubule cell chemotaxis +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] +synonym: "bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0061352 ! cell chemotaxis involved in Malpighian tubule morphogenesis +relationship: part_of GO:0061352 ! cell chemotaxis involved in Malpighian tubule morphogenesis +created_by: dph +creation_date: 2010-10-01T12:01:00Z + +[Term] +id: GO:0061354 +name: planar cell polarity pathway involved in pericardium morphogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium." [GOC:dph, GOC:mtg_heart, PMID:19056682] +is_a: GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: part_of GO:0003344 ! pericardium morphogenesis +created_by: dph +creation_date: 2010-10-01T03:12:53Z + +[Term] +id: GO:0061355 +name: Wnt protein secretion +namespace: biological_process +def: "The controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472] +is_a: GO:0009306 ! protein secretion +is_a: GO:0023061 ! signal release +relationship: part_of GO:0198738 ! cell-cell signaling by wnt +created_by: dph +creation_date: 2010-10-08T01:07:48Z + +[Term] +id: GO:0061356 +name: regulation of Wnt protein secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061355 ! Wnt protein secretion +relationship: regulates GO:0061355 ! Wnt protein secretion +created_by: dph +creation_date: 2010-10-08T01:09:51Z + +[Term] +id: GO:0061357 +name: positive regulation of Wnt protein secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0061356 ! regulation of Wnt protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061355 ! Wnt protein secretion +relationship: positively_regulates GO:0061355 ! Wnt protein secretion +created_by: dph +creation_date: 2010-10-08T01:12:21Z + +[Term] +id: GO:0061358 +name: negative regulation of Wnt protein secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell." [GOC:bf, PMID:19223472] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0061356 ! regulation of Wnt protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061355 ! Wnt protein secretion +relationship: negatively_regulates GO:0061355 ! Wnt protein secretion +created_by: dph +creation_date: 2010-10-08T01:15:15Z + +[Term] +id: GO:0061359 +name: regulation of Wnt signaling pathway by Wnt protein secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell." [GOC:bf, GOC:jl, PMID:19223472] +synonym: "regulation of Wnt receptor signaling pathway by Wnt protein secretion" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway by Wnt protein secretion" EXACT [GOC:mah] +synonym: "regulation of Wnt-activated signaling pathway by Wnt protein secretion" EXACT [GOC:signaling] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +is_a: GO:0061355 ! Wnt protein secretion +intersection_of: GO:0061355 ! Wnt protein secretion +intersection_of: regulates GO:0016055 ! Wnt signaling pathway +created_by: dph +creation_date: 2010-10-08T01:18:02Z + +[Term] +id: GO:0061360 +name: optic chiasma development +namespace: biological_process +def: "The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature." [GOC:dph] +synonym: "optic chiasm development" EXACT [GOC:dph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021554 ! optic nerve development +created_by: dph +creation_date: 2010-10-13T08:00:29Z + +[Term] +id: GO:0061361 +name: positive regulation of maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape." [GOC:dph] +is_a: GO:2000115 ! regulation of maintenance of bipolar cell polarity regulating cell shape +is_a: GO:2000247 ! positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +relationship: positively_regulates GO:0061305 ! maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-10-13T09:00:59Z + +[Term] +id: GO:0061362 +name: negative regulation of maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape." [GOC:dph] +is_a: GO:2000115 ! regulation of maintenance of bipolar cell polarity regulating cell shape +is_a: GO:2000750 ! negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +relationship: negatively_regulates GO:0061305 ! maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-10-13T09:03:42Z + +[Term] +id: GO:0061363 +name: negative regulation of progesterone biosynthesis involved in luteolysis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis." [GOC:dph] +synonym: "functional luteolysis" EXACT [GOC:dph] +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:2000183 ! negative regulation of progesterone biosynthetic process +intersection_of: GO:2000183 ! negative regulation of progesterone biosynthetic process +intersection_of: part_of GO:0001554 ! luteolysis +relationship: part_of GO:0001554 ! luteolysis +created_by: dph +creation_date: 2010-10-14T03:08:41Z + +[Term] +id: GO:0061364 +name: apoptotic process involved in luteolysis +namespace: biological_process +def: "The apoptotic process that contributes to luteolysis." [GOC:mtg_apoptosis, PMID:18566128] +synonym: "apoptosis involved in luteolysis" NARROW [] +synonym: "structural luteolysis" EXACT [GOC:dph] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022602 ! ovulation cycle process +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0001554 ! luteolysis +relationship: part_of GO:0001554 ! luteolysis +created_by: dph +creation_date: 2010-10-14T03:18:49Z + +[Term] +id: GO:0061365 +name: positive regulation of triglyceride lipase activity +namespace: biological_process +def: "Any process that increases the activity of triglyceride lipase." [GOC:dph] +synonym: "positive regulation of TAG activity" EXACT [PMID:16054079] +is_a: GO:0060193 ! positive regulation of lipase activity +intersection_of: GO:0065009 ! regulation of molecular function +intersection_of: positively_regulates GO:0004806 ! triglyceride lipase activity +relationship: positively_regulates GO:0004806 ! triglyceride lipase activity +created_by: dph +creation_date: 2010-10-15T08:27:22Z + +[Term] +id: GO:0061366 +name: behavioral response to chemical pain +namespace: biological_process +def: "Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus." [GOC:dph] +is_a: GO:0007635 ! chemosensory behavior +is_a: GO:0048266 ! behavioral response to pain +created_by: dph +creation_date: 2010-10-21T03:25:01Z + +[Term] +id: GO:0061367 +name: behavioral response to acetic acid induced pain +namespace: biological_process +def: "Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus." [GOC:dph] +is_a: GO:0061366 ! behavioral response to chemical pain +created_by: dph +creation_date: 2010-10-21T03:26:31Z + +[Term] +id: GO:0061368 +name: behavioral response to formalin induced pain +namespace: biological_process +def: "Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus." [GOC:dph] +is_a: GO:0061366 ! behavioral response to chemical pain +created_by: dph +creation_date: 2010-10-21T03:29:48Z + +[Term] +id: GO:0061369 +name: negative regulation of testicular blood vessel morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle." [GOC:BHF, GOC:dph] +synonym: "negative regulation of testicular vasculature morphogenesis" BROAD [GOC:BHF, GOC:dph] +is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis +created_by: dph +creation_date: 2010-10-27T02:47:14Z + +[Term] +id: GO:0061370 +name: testosterone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5." [GOC:dph, GOC:yaf] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0120178 ! steroid hormone biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +created_by: dph +creation_date: 2010-10-27T02:50:48Z + +[Term] +id: GO:0061371 +name: determination of heart left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of the heart with respect to the left and right halves of the organism." [GOC:dph, GOC:mtg_heart] +synonym: "determination of cardiac left/right asymmetry" EXACT [GOC:dph] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007507 ! heart development +created_by: dph +creation_date: 2010-11-03T02:13:58Z + +[Term] +id: GO:0061372 +name: activin receptor signaling pathway involved in heart jogging +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging." [GOC:dph, GOC:mtg_heart, GOC:signaling] +synonym: "activin receptor signalling pathway involved in heart jogging" EXACT [GOC:mah] +is_a: GO:0032924 ! activin receptor signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0032924 ! activin receptor signaling pathway +intersection_of: part_of GO:0003146 ! heart jogging +relationship: part_of GO:0003146 ! heart jogging +created_by: dph +creation_date: 2010-11-03T02:24:46Z + +[Term] +id: GO:0061373 +name: mammillary axonal complex development +namespace: biological_process +def: "The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain." [GOC:dph, GOC:yaf, PMID:10662642] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021767 ! mammillary body development +created_by: dph +creation_date: 2010-11-09T08:49:59Z + +[Term] +id: GO:0061374 +name: mammillothalamic axonal tract development +namespace: biological_process +def: "The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit." [GOC:dph, GOC:yaf, PMID:10662642] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061373 ! mammillary axonal complex development +created_by: dph +creation_date: 2010-11-09T08:54:43Z + +[Term] +id: GO:0061375 +name: mammillotectal axonal tract development +namespace: biological_process +def: "The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus." [GOC:dph, GOC:yaf, PMID:10662642] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061373 ! mammillary axonal complex development +created_by: dph +creation_date: 2010-11-09T09:01:14Z + +[Term] +id: GO:0061376 +name: mammillotegmental axonal tract development +namespace: biological_process +def: "The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons." [GOC:dph, GOC:yaf, PMID:10662642] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061373 ! mammillary axonal complex development +created_by: dph +creation_date: 2010-11-09T09:09:29Z + +[Term] +id: GO:0061377 +name: mammary gland lobule development +namespace: biological_process +def: "The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030879 ! mammary gland development +created_by: dph +creation_date: 2010-11-09T09:36:29Z + +[Term] +id: GO:0061378 +name: corpora quadrigemina development +namespace: biological_process +def: "The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030901 ! midbrain development +created_by: dph +creation_date: 2010-11-09T09:45:36Z + +[Term] +id: GO:0061379 +name: inferior colliculus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061378 ! corpora quadrigemina development +created_by: dph +creation_date: 2010-11-09T09:49:24Z + +[Term] +id: GO:0061380 +name: superior colliculus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain." [GOC:dph, GOC:yaf] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0061378 ! corpora quadrigemina development +created_by: dph +creation_date: 2010-11-09T09:51:00Z + +[Term] +id: GO:0061381 +name: cell migration in diencephalon +namespace: biological_process +def: "The orderly movement of a cell that will reside in the diencephalon." [GOC:dph] +is_a: GO:0021885 ! forebrain cell migration +relationship: part_of GO:0021536 ! diencephalon development +created_by: dph +creation_date: 2010-11-09T09:54:27Z + +[Term] +id: GO:0061382 +name: Malpighian tubule tip cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells." [GOC:dph, GOC:mtg_kidney_jan10, PMID:7821213] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0072002 ! Malpighian tubule development +created_by: dph +creation_date: 2010-11-23T09:52:44Z + +[Term] +id: GO:0061383 +name: trabecula morphogenesis +namespace: biological_process +def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: dph +creation_date: 2010-12-02T08:51:45Z + +[Term] +id: GO:0061384 +name: heart trabecula morphogenesis +namespace: biological_process +def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] +is_a: GO:0061383 ! trabecula morphogenesis +created_by: dph +creation_date: 2010-12-02T08:54:20Z + +[Term] +id: GO:0061385 +name: fibroblast proliferation involved in heart morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph] +is_a: GO:0048144 ! fibroblast proliferation +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +intersection_of: GO:0048144 ! fibroblast proliferation +intersection_of: part_of GO:0003007 ! heart morphogenesis +created_by: dph +creation_date: 2011-02-10T01:41:59Z + +[Term] +id: GO:0061386 +name: closure of optic fissure +namespace: biological_process +def: "The closure of the temporary ventral gap in the optic cup that contributes to its shaping." [GOC:dph] +synonym: "closure or choriod fissure" RELATED [GOC:dph] +is_a: GO:0002011 ! morphogenesis of an epithelial sheet +relationship: part_of GO:0002072 ! optic cup morphogenesis involved in camera-type eye development +created_by: dph +creation_date: 2011-03-30T08:14:59Z + +[Term] +id: GO:0061387 +name: regulation of extent of cell growth +namespace: biological_process +def: "Any process that modulates the extent of cell growth." [GOC:mah, GOC:vw] +is_a: GO:0001558 ! regulation of cell growth +relationship: part_of GO:0008361 ! regulation of cell size +created_by: dph +creation_date: 2011-07-14T10:15:42Z + +[Term] +id: GO:0061388 +name: regulation of rate of cell growth +namespace: biological_process +def: "Any process that modulates the rate of cell growth." [GOC:mah, GOC:vw] +is_a: GO:0001558 ! regulation of cell growth +created_by: dph +creation_date: 2011-07-14T10:18:06Z + +[Term] +id: GO:0061389 +name: regulation of direction of cell growth +namespace: biological_process +def: "Any process that modulates the direction of cell growth." [GOC:mah, GOC:vw] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0008360 ! regulation of cell shape +created_by: dph +creation_date: 2011-07-14T10:19:46Z + +[Term] +id: GO:0061390 +name: positive regulation of direction of cell growth +namespace: biological_process +def: "Any process that increases the direction of cell growth." [GOC:mah, GOC:vw] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0061389 ! regulation of direction of cell growth +created_by: dph +creation_date: 2011-07-14T10:22:55Z + +[Term] +id: GO:0061391 +name: negative regulation of direction of cell growth +namespace: biological_process +def: "Any process that decreases the direction of cell growth." [GOC:mah, GOC:vw] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0061389 ! regulation of direction of cell growth +created_by: dph +creation_date: 2011-07-14T10:25:55Z + +[Term] +id: GO:0061392 +name: regulation of transcription from RNA polymerase II promoter in response to osmotic stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, PMID:12086627, PMID:9858577] +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0071470 ! cellular response to osmotic stress +created_by: dph +creation_date: 2011-12-13T08:52:04Z + +[Term] +id: GO:0061393 +name: positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, PMID:12086627, PMID:9858577] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0061392 ! regulation of transcription from RNA polymerase II promoter in response to osmotic stress +created_by: dph +creation_date: 2011-12-13T08:58:20Z + +[Term] +id: GO:0061394 +name: regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance +namespace: biological_process +def: "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:dph] +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +relationship: part_of GO:0071243 ! cellular response to arsenic-containing substance +created_by: dph +creation_date: 2011-12-14T08:48:36Z + +[Term] +id: GO:0061395 +name: positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0061394 ! regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +created_by: dph +creation_date: 2011-12-14T08:53:20Z + +[Term] +id: GO:0061396 +name: obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus." [GOC:dph] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-01-10T09:07:08Z + +[Term] +id: GO:0061397 +name: obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus." [GOC:dph] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-01-10T09:14:51Z + +[Term] +id: GO:0061398 +name: obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus." [GOC:dph] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-01-10T09:17:02Z + +[Term] +id: GO:0061399 +name: positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus." [GOC:dph] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0071279 ! cellular response to cobalt ion +created_by: dph +creation_date: 2012-01-10T09:28:52Z + +[Term] +id: GO:0061400 +name: positive regulation of transcription from RNA polymerase II promoter in response to calcium ion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus." [GOC:dph] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0071277 ! cellular response to calcium ion +created_by: dph +creation_date: 2012-01-10T09:36:02Z + +[Term] +id: GO:0061401 +name: positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph] +is_a: GO:0061393 ! positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress +is_a: GO:0071476 ! cellular hypotonic response +created_by: dph +creation_date: 2012-01-10T09:43:08Z + +[Term] +id: GO:0061402 +name: positive regulation of transcription from RNA polymerase II promoter in response to acidic pH +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7." [GOC:dph, GOC:go_curators] +synonym: "positive regulation of transcription from RNA polymerase II promoter in response to acidity" BROAD [] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0071468 ! cellular response to acidic pH +created_by: dph +creation_date: 2012-01-10T03:06:32Z + +[Term] +id: GO:0061403 +name: positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0071500 ! cellular response to nitrosative stress +created_by: dph +creation_date: 2012-01-10T03:15:30Z + +[Term] +id: GO:0061404 +name: positive regulation of transcription from RNA polymerase II promoter in response to increased salt +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph] +is_a: GO:0036251 ! positive regulation of transcription from RNA polymerase II promoter in response to salt stress +is_a: GO:0071475 ! cellular hyperosmotic salinity response +created_by: dph +creation_date: 2012-01-10T03:20:40Z + +[Term] +id: GO:0061405 +name: positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0071464 ! cellular response to hydrostatic pressure +created_by: dph +creation_date: 2012-01-10T03:24:51Z + +[Term] +id: GO:0061406 +name: positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0042149 ! cellular response to glucose starvation +created_by: dph +creation_date: 2012-01-12T11:16:10Z + +[Term] +id: GO:0061407 +name: positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus." [GOC:dph] +is_a: GO:0036091 ! positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress +relationship: part_of GO:0070301 ! cellular response to hydrogen peroxide +created_by: dph +creation_date: 2012-01-12T11:39:10Z + +[Term] +id: GO:0061408 +name: positive regulation of transcription from RNA polymerase II promoter in response to heat stress +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:dph] +is_a: GO:0034605 ! cellular response to heat +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +created_by: dph +creation_date: 2012-01-12T11:50:30Z + +[Term] +id: GO:0061409 +name: positive regulation of transcription from RNA polymerase II promoter in response to freezing +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius." [GOC:dph] +is_a: GO:0061411 ! positive regulation of transcription from RNA polymerase II promoter in response to cold +is_a: GO:0071497 ! cellular response to freezing +created_by: dph +creation_date: 2012-01-12T12:11:06Z + +[Term] +id: GO:0061410 +name: positive regulation of transcription from RNA polymerase II promoter in response to ethanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus." [GOC:dph] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0071361 ! cellular response to ethanol +created_by: dph +creation_date: 2012-01-12T12:17:35Z + +[Term] +id: GO:0061411 +name: positive regulation of transcription from RNA polymerase II promoter in response to cold +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0070417 ! cellular response to cold +created_by: dph +creation_date: 2012-01-12T12:31:33Z + +[Term] +id: GO:0061412 +name: positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids." [GOC:dph] +is_a: GO:0034198 ! cellular response to amino acid starvation +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +created_by: dph +creation_date: 2012-01-12T12:54:05Z + +[Term] +id: GO:0061413 +name: regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source +namespace: biological_process +def: "A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338] +is_a: GO:0000429 ! carbon catabolite regulation of transcription from RNA polymerase II promoter +created_by: dph +creation_date: 2012-01-23T11:13:06Z + +[Term] +id: GO:0061414 +name: positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source +namespace: biological_process +def: "A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338] +is_a: GO:0000436 ! carbon catabolite activation of transcription from RNA polymerase II promoter +is_a: GO:0061413 ! regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source +created_by: dph +creation_date: 2012-01-23T11:31:27Z + +[Term] +id: GO:0061415 +name: negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source +namespace: biological_process +def: "A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources." [GOC:dph, PMID:19686338] +is_a: GO:0000437 ! carbon catabolite repression of transcription from RNA polymerase II promoter +is_a: GO:0061413 ! regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source +created_by: dph +creation_date: 2012-01-23T11:33:08Z + +[Term] +id: GO:0061416 +name: regulation of transcription from RNA polymerase II promoter in response to salt stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:dph, PMID:18667581] +is_a: GO:0061392 ! regulation of transcription from RNA polymerase II promoter in response to osmotic stress +is_a: GO:0071472 ! cellular response to salt stress +created_by: dph +creation_date: 2012-01-23T12:56:36Z + +[Term] +id: GO:0061417 +name: negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:dph, PMID:9767597] +is_a: GO:0043619 ! regulation of transcription from RNA polymerase II promoter in response to oxidative stress +is_a: GO:0097201 ! negative regulation of transcription from RNA polymerase II promoter in response to stress +created_by: dph +creation_date: 2012-01-23T01:02:10Z + +[Term] +id: GO:0061418 +name: regulation of transcription from RNA polymerase II promoter in response to hypoxia +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph, PMID:12511571] +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +relationship: part_of GO:0071456 ! cellular response to hypoxia +created_by: dph +creation_date: 2012-01-23T01:05:59Z + +[Term] +id: GO:0061419 +name: positive regulation of transcription from RNA polymerase II promoter in response to hypoxia +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0061418 ! regulation of transcription from RNA polymerase II promoter in response to hypoxia +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +created_by: dph +creation_date: 2012-01-23T01:07:43Z + +[Term] +id: GO:0061420 +name: regulation of transcription from RNA polymerase II promoter in response to biotin starvation +namespace: biological_process +def: "Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin." [GOC:dph, PMID:16533810] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +created_by: dph +creation_date: 2012-01-25T09:55:39Z + +[Term] +id: GO:0061421 +name: positive regulation of transcription by oleic acid +namespace: biological_process +def: "Any process involving oleic acid that activates or increases the rate of transcription." [GOC:dph, PMID:20395639] +is_a: GO:0045991 ! carbon catabolite activation of transcription +created_by: dph +creation_date: 2012-01-25T10:11:39Z + +[Term] +id: GO:0061422 +name: positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0." [GOC:dph, PMID:11523797, PMID:15299026, PMID:21749328] +synonym: "positive regulation of transcription from RNA polymerase II promoter in response to alkalinity" BROAD [] +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +is_a: GO:0071469 ! cellular response to alkaline pH +created_by: dph +creation_date: 2012-01-26T12:42:21Z + +[Term] +id: GO:0061423 +name: positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, PMID:11523797] +is_a: GO:0010765 ! positive regulation of sodium ion transport +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: positively_regulates GO:0006814 ! sodium ion transport +created_by: dph +creation_date: 2012-01-26T12:52:05Z + +[Term] +id: GO:0061424 +name: obsolete positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization." [GOC:dph, PMID:7500953] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of peroxisome organisation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:mah] +is_obsolete: true +created_by: dph +creation_date: 2012-02-02T12:50:36Z + +[Term] +id: GO:0061425 +name: positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process." [GOC:dph, PMID:10608811, PMID:7760841] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1900066 ! positive regulation of ethanol catabolic process +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: positively_regulates GO:0006068 ! ethanol catabolic process +created_by: dph +creation_date: 2012-02-02T01:12:36Z + +[Term] +id: GO:0061426 +name: positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport." [GOC:dph, PMID:10234785, PMID:10870099] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1900072 ! positive regulation of sulfite transport +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: positively_regulates GO:0000316 ! sulfite transport +created_by: dph +creation_date: 2012-02-02T01:21:46Z + +[Term] +id: GO:0061427 +name: obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process." [GOC:dph, PMID:15302821] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-02-02T01:30:41Z + +[Term] +id: GO:0061428 +name: negative regulation of transcription from RNA polymerase II promoter in response to hypoxia +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus." [GOC:dph, PMID:17785431] +is_a: GO:0061418 ! regulation of transcription from RNA polymerase II promoter in response to hypoxia +is_a: GO:0097201 ! negative regulation of transcription from RNA polymerase II promoter in response to stress +created_by: dph +creation_date: 2012-02-06T09:26:05Z + +[Term] +id: GO:0061429 +name: positive regulation of transcription from RNA polymerase II promoter by oleic acid +namespace: biological_process +def: "Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dph, PMID:20395639] +is_a: GO:0000436 ! carbon catabolite activation of transcription from RNA polymerase II promoter +is_a: GO:0061421 ! positive regulation of transcription by oleic acid +created_by: dph +creation_date: 2012-02-07T09:54:49Z + +[Term] +id: GO:0061430 +name: bone trabecula morphogenesis +namespace: biological_process +def: "The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:BHF, GOC:dph, GOC:vk] +is_a: GO:0061383 ! trabecula morphogenesis +created_by: dph +creation_date: 2012-02-07T10:15:36Z + +[Term] +id: GO:0061431 +name: cellular response to methionine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus." [GOC:dph, PMID:7891681] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1904640 ! response to methionine +created_by: dph +creation_date: 2012-02-07T10:27:01Z + +[Term] +id: GO:0061432 +name: obsolete regulation of transcription from RNA polymerase II promoter in response to methionine +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus." [GOC:dph, PMID:7891681] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-02-07T10:33:35Z + +[Term] +id: GO:0061433 +name: cellular response to caloric restriction +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake." [GOC:dph, PMID:17914901] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0061771 ! response to caloric restriction +created_by: dph +creation_date: 2012-02-09T09:03:15Z + +[Term] +id: GO:0061434 +name: obsolete regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus." [GOC:dph, PMID:17914901] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2012-02-09T09:06:09Z + +[Term] +id: GO:0061435 +name: positive regulation of transcription from a mobile element promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter." [GOC:dph, PMID:12230120, PMID:9271107] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +created_by: dph +creation_date: 2012-02-09T10:01:33Z + +[Term] +id: GO:0061436 +name: establishment of skin barrier +namespace: biological_process +def: "Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability." [GOC:dph] +synonym: "epithelial barrier development" RELATED [GOC:dph] +synonym: "establishment of epithelial barrier" BROAD [GOC:dph] +synonym: "skin barrier development" RELATED [GOC:dph] +is_a: GO:0033561 ! regulation of water loss via skin +relationship: part_of GO:0043588 ! skin development +created_by: dph +creation_date: 2012-03-02T09:14:26Z + +[Term] +id: GO:0061437 +name: renal system vasculature development +namespace: biological_process +def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] +is_a: GO:0001944 ! vasculature development +relationship: part_of GO:0072001 ! renal system development +created_by: dph +creation_date: 2012-03-08T12:16:24Z + +[Term] +id: GO:0061438 +name: renal system vasculature morphogenesis +namespace: biological_process +def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0061437 ! renal system vasculature development +created_by: dph +creation_date: 2012-03-08T12:21:56Z + +[Term] +id: GO:0061439 +name: kidney vasculature morphogenesis +namespace: biological_process +def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0061438 ! renal system vasculature morphogenesis +relationship: part_of GO:0061440 ! kidney vasculature development +created_by: dph +creation_date: 2012-03-08T12:30:11Z + +[Term] +id: GO:0061440 +name: kidney vasculature development +namespace: biological_process +def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] +is_a: GO:0061437 ! renal system vasculature development +relationship: part_of GO:0001822 ! kidney development +created_by: dph +creation_date: 2012-03-08T12:39:09Z + +[Term] +id: GO:0061441 +name: renal artery morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195] +is_a: GO:0048844 ! artery morphogenesis +relationship: part_of GO:0061439 ! kidney vasculature morphogenesis +created_by: dph +creation_date: 2012-03-08T12:42:09Z + +[Term] +id: GO:0061442 +name: cardiac muscle cell fate determination +namespace: biological_process +def: "The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:BHF, GOC:dph] +is_a: GO:0007521 ! muscle cell fate determination +is_a: GO:0060913 ! cardiac cell fate determination +relationship: part_of GO:0060923 ! cardiac muscle cell fate commitment +created_by: dph +creation_date: 2012-03-13T08:59:57Z + +[Term] +id: GO:0061443 +name: endocardial cushion cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell." [GOC:BHF, GOC:dph] +is_a: GO:0035051 ! cardiocyte differentiation +relationship: part_of GO:0003197 ! endocardial cushion development +created_by: dph +creation_date: 2012-03-13T09:05:38Z + +[Term] +id: GO:0061444 +name: endocardial cushion cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state." [GOC:BHF, GOC:dph] +is_a: GO:0055006 ! cardiac cell development +relationship: part_of GO:0061443 ! endocardial cushion cell differentiation +created_by: dph +creation_date: 2012-03-13T09:07:46Z + +[Term] +id: GO:0061445 +name: endocardial cushion cell fate commitment +namespace: biological_process +def: "The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell." [GOC:BHF, GOC:dph] +is_a: GO:0060957 ! endocardial cell fate commitment +relationship: part_of GO:0061443 ! endocardial cushion cell differentiation +created_by: dph +creation_date: 2012-03-13T09:11:03Z + +[Term] +id: GO:0061446 +name: endocardial cushion cell fate determination +namespace: biological_process +def: "The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [GOC:BHF, GOC:dph] +is_a: GO:0060913 ! cardiac cell fate determination +relationship: part_of GO:0061445 ! endocardial cushion cell fate commitment +created_by: dph +creation_date: 2012-03-13T09:22:13Z + +[Term] +id: GO:0061447 +name: endocardial cushion cell fate specification +namespace: biological_process +def: "The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:BHF, GOC:dph] +is_a: GO:0060912 ! cardiac cell fate specification +relationship: part_of GO:0061445 ! endocardial cushion cell fate commitment +created_by: dph +creation_date: 2012-03-13T09:25:56Z + +[Term] +id: GO:0061448 +name: connective tissue development +namespace: biological_process +def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF] +is_a: GO:0009888 ! tissue development +created_by: dph +creation_date: 2012-03-22T12:53:41Z + +[Term] +id: GO:0061449 +name: olfactory bulb tufted cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] +is_a: GO:0021954 ! central nervous system neuron development +relationship: part_of GO:0021772 ! olfactory bulb development +created_by: dph +creation_date: 2012-05-15T12:30:21Z + +[Term] +id: GO:0061450 +name: trophoblast cell migration +namespace: biological_process +def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph] +is_a: GO:0001667 ! ameboidal-type cell migration +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0007566 ! embryo implantation +created_by: dph +creation_date: 2012-07-10T08:38:37Z + +[Term] +id: GO:0061451 +name: retrotrapezoid nucleus development +namespace: biological_process +def: "The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration." [GOC:dph] +is_a: GO:0048857 ! neural nucleus development +relationship: part_of GO:0021550 ! medulla oblongata development +created_by: dph +creation_date: 2012-07-19T12:38:30Z + +[Term] +id: GO:0061452 +name: retrotrapezoid nucleus neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus." [GOC:dph] +is_a: GO:0021953 ! central nervous system neuron differentiation +relationship: part_of GO:0061451 ! retrotrapezoid nucleus development +created_by: dph +creation_date: 2012-07-19T12:43:18Z + +[Term] +id: GO:0061453 +name: interstitial cell of Cajal differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph] +synonym: "ICC differentiation" RELATED [GOC:dph] +is_a: GO:0060563 ! neuroepithelial cell differentiation +is_a: GO:0060575 ! intestinal epithelial cell differentiation +created_by: dph +creation_date: 2012-07-20T08:20:50Z + +[Term] +id: GO:0061454 +name: release of sequestered calcium ion into cytosol by Golgi +namespace: biological_process +def: "The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol." [GOC:dph, GOC:tb] +synonym: "Golgi calcium ion export" BROAD [] +is_a: GO:0051209 ! release of sequestered calcium ion into cytosol +is_a: GO:0061856 ! Golgi calcium ion transmembrane transport +created_by: dph +creation_date: 2012-07-27T02:29:43Z + +[Term] +id: GO:0061455 +name: integral component of muscle cell projection membrane +namespace: cellular_component +def: "The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:dph, GOC:tb] +synonym: "integral to muscle cell projection membrane" EXACT [] +is_a: GO:0005887 ! integral component of plasma membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0036195 ! muscle cell projection membrane +relationship: part_of GO:0036195 ! muscle cell projection membrane +created_by: dph +creation_date: 2012-07-27T02:38:01Z + +[Term] +id: GO:0061456 +name: mesenchymal stem cell migration involved in uteric bud morphogenesis +namespace: biological_process +def: "The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:dph, GOC:tb] +is_a: GO:0035787 ! cell migration involved in kidney development +relationship: part_of GO:0060675 ! ureteric bud morphogenesis +created_by: dph +creation_date: 2012-08-22T17:19:22Z + +[Term] +id: GO:0061457 +name: mesonephric cell migration involved in male gonad development +namespace: biological_process +def: "The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development." [GOC:dph, GOC:tb] +is_a: GO:0016477 ! cell migration +created_by: dph +creation_date: 2012-08-22T17:31:00Z + +[Term] +id: GO:0061458 +name: reproductive system development +namespace: biological_process +def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph] +is_a: GO:0048731 ! system development +created_by: dph +creation_date: 2012-08-22T17:47:53Z + +[Term] +id: GO:0061459 +name: L-arginine transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015598 +alt_id: GO:0102022 +def: "Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane." [GOC:dph] +synonym: "arginine porter activity" NARROW [] +synonym: "arginine-importing ATPase activity" NARROW [] +synonym: "ATP-dependent L-arginine transmembrane transporter activity" NARROW [] +synonym: "ATPase-coupled L-arginine transmembrane transporter activity" NARROW [] +synonym: "L-arginine-importing ATPase activity" NARROW [] +is_a: GO:0015179 ! L-amino acid transmembrane transporter activity +is_a: GO:0015181 ! arginine transmembrane transporter activity +relationship: part_of GO:1903400 ! L-arginine transmembrane transport +created_by: dph +creation_date: 2012-09-25T08:37:29Z + +[Term] +id: GO:0061462 +name: protein localization to lysosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a lysosome." [GOC:dph] +is_a: GO:0072665 ! protein localization to vacuole +created_by: dph +creation_date: 2012-10-05T10:50:51Z + +[Term] +id: GO:0061463 +name: O-acetyl-ADP-ribose deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate." [GOC:dph] +is_a: GO:0019213 ! deacetylase activity +created_by: dph +creation_date: 2012-10-05T11:05:06Z + +[Term] +id: GO:0061464 +name: obsolete plasma membrane part of cell-substrate junction +namespace: cellular_component +def: "OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell-substrate junction." [GOC:dph] +comment: The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM. +is_obsolete: true +created_by: dph +creation_date: 2012-10-19T11:04:48Z + +[Term] +id: GO:0061465 +name: obsolete plasma membrane part of hemidesmosome +namespace: cellular_component +def: "OBSOLETE. The part of the plasma membrane that contributes to the structure of a hemidesmosome." [GOC:dph] +comment: The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM. +is_obsolete: true +created_by: dph +creation_date: 2012-10-19T13:47:25Z + +[Term] +id: GO:0061466 +name: obsolete plasma membrane part of cell junction +namespace: cellular_component +def: "OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell junction." [GOC:dph] +comment: The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM. +is_obsolete: true +created_by: dph +creation_date: 2012-10-19T13:53:44Z + +[Term] +id: GO:0061468 +name: karyomere +namespace: cellular_component +def: "A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division." [GOC:dph, PMID:12734396, PMID:22863006] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +created_by: dph +creation_date: 2012-10-22T14:19:29Z + +[Term] +id: GO:0061469 +name: regulation of type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044342 ! type B pancreatic cell proliferation +relationship: regulates GO:0044342 ! type B pancreatic cell proliferation +created_by: dph +creation_date: 2012-11-01T13:16:23Z + +[Term] +id: GO:0061470 +name: T follicular helper cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell." [GOC:dph, PMID:21572431] +synonym: "T-helper follicular cell differentiation" EXACT [GOC:dph] +is_a: GO:0042093 ! T-helper cell differentiation +created_by: dph +creation_date: 2012-11-02T09:01:48Z + +[Term] +id: GO:0061471 +name: karyomere assembly +namespace: biological_process +def: "The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle." [GOC:dph, PMID:9732278] +is_a: GO:0070925 ! organelle assembly +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007084 ! mitotic nuclear envelope reassembly +created_by: dph +creation_date: 2012-11-02T09:13:59Z + +[Term] +id: GO:0061472 +name: karyomere membrane fusion +namespace: biological_process +def: "Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus." [GOC:dph, PMID:2734396] +is_a: GO:0090174 ! organelle membrane fusion +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007084 ! mitotic nuclear envelope reassembly +created_by: dph +creation_date: 2012-11-02T09:25:41Z + +[Term] +id: GO:0061473 +name: murein tripeptide carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate." [GOC:dph, PMID:22970852] +is_a: GO:0004181 ! metallocarboxypeptidase activity +created_by: dph +creation_date: 2012-11-06T12:23:39Z + +[Term] +id: GO:0061474 +name: phagolysosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a phagolysosome." [GOC:dph, PMID:22073313] +is_a: GO:0005765 ! lysosomal membrane +is_a: GO:0030670 ! phagocytic vesicle membrane +relationship: part_of GO:0032010 ! phagolysosome +created_by: dph +creation_date: 2012-11-06T12:26:18Z + +[Term] +id: GO:0061475 +name: cytosolic valyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:dph] +is_a: GO:0006438 ! valyl-tRNA aminoacylation +intersection_of: GO:0006438 ! valyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005829 ! cytosol +relationship: occurs_in GO:0005829 ! cytosol +created_by: dph +creation_date: 2012-11-06T12:29:42Z + +[Term] +id: GO:0061476 +name: response to anticoagulant +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus." [GOC:dph] +is_a: GO:0042493 ! response to drug +created_by: dph +creation_date: 2012-11-07T09:07:00Z + +[Term] +id: GO:0061477 +name: response to aromatase inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus." [GOC:dph] +is_a: GO:0042221 ! response to chemical +created_by: dph +creation_date: 2012-11-07T09:08:36Z + +[Term] +id: GO:0061478 +name: response to platelet aggregation inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus." [GOC:dph] +is_a: GO:0042493 ! response to drug +created_by: dph +creation_date: 2012-11-07T09:09:37Z + +[Term] +id: GO:0061479 +name: response to reverse transcriptase inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus." [GOC:dph] +is_a: GO:0046677 ! response to antibiotic +created_by: dph +creation_date: 2012-11-07T09:10:51Z + +[Term] +id: GO:0061480 +name: response to asparaginase +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus." [GOC:dph] +is_a: GO:0042221 ! response to chemical +created_by: dph +creation_date: 2012-11-07T09:13:08Z + +[Term] +id: GO:0061481 +name: response to TNF agonist +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus." [GOC:dph] +is_a: GO:0042221 ! response to chemical +created_by: dph +creation_date: 2012-11-07T09:14:07Z + +[Term] +id: GO:0061482 +name: response to irinotecan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus." [GOC:dph] +is_a: GO:0042221 ! response to chemical +created_by: dph +creation_date: 2012-11-07T09:15:03Z + +[Term] +id: GO:0061483 +name: sulfinylpropanyl adenylate synthase +namespace: molecular_function +def: "Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate." [GOC:dph, PMID:8346915] +synonym: "SPA synthase" RELATED [PMID:8346915] +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +created_by: dph +creation_date: 2012-11-16T10:08:15Z + +[Term] +id: GO:0061484 +name: hematopoietic stem cell homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411] +is_a: GO:0048872 ! homeostasis of number of cells +created_by: dph +creation_date: 2012-12-04T09:41:02Z + +[Term] +id: GO:0061485 +name: memory T cell proliferation +namespace: biological_process +def: "The expansion of a memory T cell population by cell division." [GOC:dph, PMID:14647273] +is_a: GO:0042098 ! T cell proliferation +created_by: dph +creation_date: 2012-12-04T09:52:54Z + +[Term] +id: GO:0061486 +name: high-affinity fructose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:dph, PMID:10735857] +synonym: "high affinity fructose transmembrane transporter activity" EXACT [] +is_a: GO:0005353 ! fructose transmembrane transporter activity +created_by: dph +creation_date: 2012-12-04T10:34:55Z + +[Term] +id: GO:0061487 +name: obsolete DNA replication initiation from late origin +namespace: biological_process +def: "OBSOLETE. The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase." [GOC:dph, PMID:19221029] +comment: The reason for obsoletion is that there is no evidence that this is a different process from its parent term (DNA replication initiation, GO:0006270), but only that regulation of initiation at late origins differs from regulation of initiation at early origins. +synonym: "late replication origin firing" EXACT [GOC:dph, PMID:19221029] +is_obsolete: true +consider: GO:0101017 +created_by: dph +creation_date: 2012-12-06T11:21:48Z + +[Term] +id: GO:0061492 +name: asymmetric protein localization to old or new spindle pole body +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, PMID:22119525] +is_a: GO:0071988 ! protein localization to spindle pole body +created_by: dph +creation_date: 2012-12-06T15:23:15Z + +[Term] +id: GO:0061493 +name: central plaque of mitotic spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the mitotic spindle pole body; the central plaque is embedded in the nuclear envelope." [GOC:dph] +is_a: GO:0005823 ! central plaque of spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:08:26Z + +[Term] +id: GO:0061494 +name: gamma-tubulin large complex, mitotic spindle pole body +namespace: cellular_component +def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the mitotic spindle pole body." [GOC:dph] +is_a: GO:0055032 ! gamma-tubulin large complex, spindle pole body +intersection_of: GO:0000931 ! gamma-tubulin large complex +intersection_of: part_of GO:0044732 ! mitotic spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:10:00Z + +[Term] +id: GO:0061495 +name: gamma-tubulin small complex, mitotic spindle pole body +namespace: cellular_component +def: "A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the mitotic spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae." [GOC:dph] +is_a: GO:0000928 ! gamma-tubulin small complex, spindle pole body +intersection_of: GO:0008275 ! gamma-tubulin small complex +intersection_of: part_of GO:0044732 ! mitotic spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:11:27Z + +[Term] +id: GO:0061496 +name: half bridge of mitotic spindle pole body +namespace: cellular_component +def: "Structure adjacent to the plaques of the mitotic spindle pole body." [GOC:dph] +is_a: GO:0005825 ! half bridge of spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:13:52Z + +[Term] +id: GO:0061497 +name: inner plaque of mitotic spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus." [GOC:dph, GOC:vw] +is_a: GO:0005822 ! inner plaque of spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:15:12Z + +[Term] +id: GO:0061498 +name: intermediate layer of mitotic spindle pole body +namespace: cellular_component +def: "Structure between the central and outer plaques of the mitotic spindle pole body." [GOC:dph] +is_a: GO:0005821 ! intermediate layer of spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:17:14Z + +[Term] +id: GO:0061499 +name: outer plaque of mitotic spindle pole body +namespace: cellular_component +def: "One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm." [GOC:dph] +is_a: GO:0005824 ! outer plaque of spindle pole body +relationship: part_of GO:0044732 ! mitotic spindle pole body +created_by: dph +creation_date: 2012-12-11T09:18:43Z + +[Term] +id: GO:0061500 +name: gene conversion at mating-type locus, termination of copy-synthesis +namespace: biological_process +def: "A DNA replication termination process that is part of gene conversion at a mating-type locus and takes place at a specific termination site." [GOC:dph, PMID:10716938] +is_a: GO:0022414 ! reproductive process +is_a: GO:0071170 ! site-specific DNA replication termination +intersection_of: GO:0071170 ! site-specific DNA replication termination +intersection_of: part_of GO:0007534 ! gene conversion at mating-type locus +relationship: part_of GO:0007534 ! gene conversion at mating-type locus +created_by: dph +creation_date: 2012-12-11T09:32:31Z + +[Term] +id: GO:0061501 +name: cyclic-GMP-AMP synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP." [GOC:dph, PMID:23258413] +xref: Reactome:R-HSA-3244614 "cGAS produces cyclic GMP-AMP" +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: dph +creation_date: 2013-01-04T07:17:57Z + +[Term] +id: GO:0061502 +name: early endosome to recycling endosome transport +namespace: biological_process +def: "The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes." [GOC:dph, GOC:kmv, PMID:21474295] +is_a: GO:0016482 ! cytosolic transport +is_a: GO:0098927 ! vesicle-mediated transport between endosomal compartments +created_by: dph +creation_date: 2013-01-04T07:24:56Z + +[Term] +id: GO:0061503 +name: tRNA threonylcarbamoyladenosine dehydratase +namespace: molecular_function +def: "Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A." [GOC:dph, PMID:23242255] +is_a: GO:0016836 ! hydro-lyase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +created_by: dph +creation_date: 2013-01-22T14:22:14Z + +[Term] +id: GO:0061504 +name: cyclic threonylcarbamoyladenosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules." [PMID:23242255] +is_a: GO:0006400 ! tRNA modification +created_by: dph +creation_date: 2013-01-22T14:25:00Z + +[Term] +id: GO:0061506 +name: obsolete DNA topoisomerase type II (ATP-independent) activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:dph] +comment: This term was made obsolete because there is no evidence that this function exists. There are no known type II topoisomerase enzymes that are ATP-independent; as far as we know, ALL type II topoisomerase enzymes utilize hydrolysis of ATP. +is_obsolete: true +created_by: dph +creation_date: 2013-01-23T10:41:58Z + +[Term] +id: GO:0061507 +name: cyclic-GMP-AMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cyclic-GMP-AMP (cGAMP) cyclic nucleotide." [GOC:dph, PMID:23258412] +is_a: GO:0030551 ! cyclic nucleotide binding +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +created_by: dph +creation_date: 2013-01-24T15:38:27Z + +[Term] +id: GO:0061508 +name: CDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into CDP to produce a CTP." [PMID:7499258] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +created_by: dph +creation_date: 2013-02-21T13:38:11Z + +[Term] +id: GO:0061509 +name: asymmetric protein localization to old mitotic spindle pole body +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, GOC:vw] +is_a: GO:0061492 ! asymmetric protein localization to old or new spindle pole body +is_a: GO:1902440 ! protein localization to mitotic spindle pole body +created_by: dph +creation_date: 2013-02-21T13:49:26Z + +[Term] +id: GO:0061510 +name: asymmetric protein localization to new mitotic spindle pole body +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically." [GOC:dph, GOC:vw] +is_a: GO:0061492 ! asymmetric protein localization to old or new spindle pole body +is_a: GO:1902440 ! protein localization to mitotic spindle pole body +created_by: dph +creation_date: 2013-02-21T13:49:54Z + +[Term] +id: GO:0061511 +name: centriole elongation +namespace: biological_process +def: "The centrosome organization process by which a centriole increases in length as part of the process of replication." [GOC:dph, PMID:21576394] +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0007099 ! centriole replication +created_by: dph +creation_date: 2013-03-22T09:06:27Z + +[Term] +id: GO:0061512 +name: protein localization to cilium +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph] +is_a: GO:0033365 ! protein localization to organelle +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +property_value: RO:0002161 NCBITaxon:4890 +property_value: RO:0002161 NCBITaxon:5782 +created_by: dph +creation_date: 2013-03-22T15:41:44Z + +[Term] +id: GO:0061513 +name: glucose 6-phosphate:inorganic phosphate antiporter activity +namespace: molecular_function +alt_id: GO:0008524 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out)." [GOC:dph, PMID:18337460] +synonym: "glucose 6-phosphate:phosphate antiporter activity" BROAD [] +xref: Reactome:R-HSA-198513 "Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4" +xref: Reactome:R-HSA-3229118 "Defective SLC37A4 does not exchange G6P and Pi across the ER membrane" +xref: Reactome:R-HSA-3257122 "SLC37A1, SLC37A2 exchange G6P for Pi across the endoplasmic reticulum membrane" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015526 ! hexose-phosphate:inorganic phosphate antiporter activity +created_by: dph +creation_date: 2013-04-17T08:47:40Z + +[Term] +id: GO:0061514 +name: interleukin-34-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:dph, PMID:18467591] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: dph +creation_date: 2013-04-18T13:00:33Z + +[Term] +id: GO:0061515 +name: myeloid cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0030099 ! myeloid cell differentiation +created_by: dph +creation_date: 2013-04-18T13:03:16Z + +[Term] +id: GO:0061516 +name: monocyte proliferation +namespace: biological_process +def: "The expansion of a monocyte population by cell division." [GOC:dph, PMID:18467591] +is_a: GO:0070661 ! leukocyte proliferation +created_by: dph +creation_date: 2013-04-18T13:14:24Z + +[Term] +id: GO:0061517 +name: macrophage proliferation +namespace: biological_process +def: "The expansion of a macrophage population by cell division." [GOC:dph, PMID:12614284, PMID:19466391] +is_a: GO:0070661 ! leukocyte proliferation +created_by: dph +creation_date: 2013-04-18T13:17:56Z + +[Term] +id: GO:0061518 +name: microglial cell proliferation +namespace: biological_process +def: "The expansion of a microglial cell population by cell division." [GOC:dph, PMID:17344397] +is_a: GO:0014009 ! glial cell proliferation +is_a: GO:0061517 ! macrophage proliferation +created_by: dph +creation_date: 2013-04-18T13:20:21Z + +[Term] +id: GO:0061519 +name: macrophage homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:dph, PMID:21727904] +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis +created_by: dph +creation_date: 2013-04-18T13:25:33Z + +[Term] +id: GO:0061520 +name: Langerhans cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a Langerhans cell." [GOC:dph, PMID:22729249] +is_a: GO:0043011 ! myeloid dendritic cell differentiation +created_by: dph +creation_date: 2013-04-18T13:29:07Z + +[Term] +id: GO:0061521 +name: hepatic stellate cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell." [GOC:dph, PMID:9407545] +is_a: GO:0030154 ! cell differentiation +created_by: dph +creation_date: 2013-04-18T13:36:08Z + +[Term] +id: GO:0061522 +name: 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity +namespace: molecular_function +def: "Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA." [GOC:dph] +is_a: GO:0016289 ! CoA hydrolase activity +created_by: dph +creation_date: 2013-04-18T14:37:32Z + +[Term] +id: GO:0061523 +name: cilium disassembly +namespace: biological_process +def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +synonym: "cilium resorption" EXACT [GOC:dph] +is_a: GO:0044782 ! cilium organization +is_a: GO:1903008 ! organelle disassembly +created_by: dph +creation_date: 2013-04-18T14:59:59Z + +[Term] +id: GO:0061524 +name: central canal development +namespace: biological_process +def: "The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [GOC:cvs, GOC:dph, PMID:23409159] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021510 ! spinal cord development +created_by: dph +creation_date: 2013-04-20T08:18:31Z + +[Term] +id: GO:0061525 +name: hindgut development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph] +is_a: GO:0048565 ! digestive tract development +created_by: dph +creation_date: 2013-06-14T11:22:21Z + +[Term] +id: GO:0061526 +name: acetylcholine secretion +namespace: biological_process +def: "The regulated release of acetylcholine by a cell." [GOC:dph] +is_a: GO:0015870 ! acetylcholine transport +is_a: GO:0023061 ! signal release +created_by: dph +creation_date: 2013-06-21T15:40:39Z + +[Term] +id: GO:0061527 +name: dopamine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0099124 ! axonal dopamine secretion +relationship: part_of GO:0001963 ! synaptic transmission, dopaminergic +created_by: dph +creation_date: 2013-06-21T15:43:15Z + +[Term] +id: GO:0061528 +name: aspartate secretion +namespace: biological_process +def: "The regulated release of aspartate by a cell." [GOC:dph] +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0046717 ! acid secretion +created_by: dph +creation_date: 2013-06-21T15:45:37Z + +[Term] +id: GO:0061529 +name: epinephrine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter." [GOC:dph] +synonym: "adrenaline secretion, neurotransmission" EXACT [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0048242 ! epinephrine secretion +created_by: dph +creation_date: 2013-06-21T15:47:22Z + +[Term] +id: GO:0061530 +name: aspartate secretion, neurotransmission +namespace: biological_process +def: "The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0061528 ! aspartate secretion +created_by: dph +creation_date: 2013-06-21T15:50:10Z + +[Term] +id: GO:0061531 +name: primary amine secretion +namespace: biological_process +def: "The regulated release of a primary amine by a cell." [GOC:dph] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015837 ! amine transport +is_a: GO:0032940 ! secretion by cell +created_by: dph +creation_date: 2013-06-21T15:56:08Z + +[Term] +id: GO:0061532 +name: primary amine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0061545 ! tyramine secretion +created_by: dph +creation_date: 2013-06-21T15:57:12Z + +[Term] +id: GO:0061533 +name: norepinephrine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph] +synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0048243 ! norepinephrine secretion +created_by: dph +creation_date: 2013-06-21T16:05:08Z + +[Term] +id: GO:0061534 +name: gamma-aminobutyric acid secretion, neurotransmission +namespace: biological_process +def: "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0014051 ! gamma-aminobutyric acid secretion +relationship: part_of GO:0051932 ! synaptic transmission, GABAergic +created_by: dph +creation_date: 2013-06-21T16:10:50Z + +[Term] +id: GO:0061535 +name: glutamate secretion, neurotransmission +namespace: biological_process +def: "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0014047 ! glutamate secretion +relationship: part_of GO:0035249 ! synaptic transmission, glutamatergic +created_by: dph +creation_date: 2013-06-21T16:14:47Z + +[Term] +id: GO:0061536 +name: glycine secretion +namespace: biological_process +def: "The controlled release of glycine by a cell." [GOC:dph] +is_a: GO:0015816 ! glycine transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0046717 ! acid secretion +created_by: dph +creation_date: 2013-06-21T16:18:23Z + +[Term] +id: GO:0061537 +name: glycine secretion, neurotransmission +namespace: biological_process +def: "The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0061536 ! glycine secretion +relationship: part_of GO:0060012 ! synaptic transmission, glycinergic +created_by: dph +creation_date: 2013-06-21T16:19:02Z + +[Term] +id: GO:0061538 +name: histamine secretion, neurotransmission +namespace: biological_process +def: "The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0001821 ! histamine secretion +is_a: GO:0007269 ! neurotransmitter secretion +created_by: dph +creation_date: 2013-06-21T16:21:21Z + +[Term] +id: GO:0061539 +name: octopamine secretion +namespace: biological_process +def: "The controlled release of octopamine by a cell." [GOC:dph] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0032940 ! secretion by cell +is_a: GO:0071705 ! nitrogen compound transport +created_by: dph +creation_date: 2013-06-21T16:24:02Z + +[Term] +id: GO:0061540 +name: octopamine secretion, neurotransmission +namespace: biological_process +def: "The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:0061539 ! octopamine secretion +created_by: dph +creation_date: 2013-06-21T16:24:47Z + +[Term] +id: GO:0061541 +name: rhabdomere morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments." [GOC:dph, PMID:22113834] +is_a: GO:0048812 ! neuron projection morphogenesis +relationship: part_of GO:0008594 ! photoreceptor cell morphogenesis +relationship: part_of GO:0042052 ! rhabdomere development +created_by: dph +creation_date: 2013-06-24T07:59:25Z + +[Term] +id: GO:0061542 +name: 3-demethylubiquinol-n 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n." [EC:2.1.1.64, GOC:dph] +synonym: "2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase" NARROW [] +synonym: "5-demethylubiquinone-10 methyltransferase" NARROW [] +synonym: "5-demethylubiquinone-9 methyltransferase" NARROW [] +synonym: "OMHMB-methyltransferase" RELATED [] +synonym: "S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase" RELATED [] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: dph +creation_date: 2013-06-25T08:01:46Z + +[Term] +id: GO:0061543 +name: 3-demethylubiquinol-6 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6." [GOC:dph] +is_a: GO:0061542 ! 3-demethylubiquinol-n 3-O-methyltransferase activity +created_by: dph +creation_date: 2013-06-25T08:05:14Z + +[Term] +id: GO:0061544 +name: peptide secretion, neurotransmission +namespace: biological_process +def: "The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter." [GOC:dph] +is_a: GO:0002790 ! peptide secretion +is_a: GO:0007269 ! neurotransmitter secretion +created_by: dph +creation_date: 2013-06-25T09:10:10Z + +[Term] +id: GO:0061545 +name: tyramine secretion +namespace: biological_process +def: "The regulated release of a tyramine by a cell." [GOC:dph] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015844 ! monoamine transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0061531 ! primary amine secretion +created_by: dph +creation_date: 2013-06-25T09:14:07Z + +[Term] +id: GO:0061546 +name: tyramine secretion, neurotransmission +namespace: biological_process +def: "The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter." [GOC:dph] +is_a: GO:0061532 ! primary amine secretion, neurotransmission +created_by: dph +creation_date: 2013-06-25T09:16:47Z + +[Term] +id: GO:0061547 +name: glycogen synthase activity, transferring glucose-1-phosphate +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate." [GOC:dph, PMID:21356517] +xref: Reactome:R-HSA-3780994 "GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2" +xref: Reactome:R-HSA-3781024 "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1" +is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups +created_by: dph +creation_date: 2013-07-02T09:59:18Z + +[Term] +id: GO:0061548 +name: ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph] +synonym: "ganglia development" RELATED [GOC:dph] +synonym: "gangliogenesis" NARROW [GOC:BHF, GOC:rl] +is_a: GO:0009888 ! tissue development +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0007399 ! nervous system development +created_by: dph +creation_date: 2013-07-10T08:36:12Z + +[Term] +id: GO:0061549 +name: sympathetic ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl] +synonym: "sympathetic ganglia development" RELATED [GOC:dph] +is_a: GO:0061548 ! ganglion development +relationship: part_of GO:0048485 ! sympathetic nervous system development +created_by: dph +creation_date: 2013-07-10T08:38:01Z + +[Term] +id: GO:0061550 +name: cranial ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph] +synonym: "cranial ganglia development" RELATED [GOC:dph] +is_a: GO:0061548 ! ganglion development +relationship: part_of GO:0021545 ! cranial nerve development +created_by: dph +creation_date: 2013-07-10T08:40:14Z + +[Term] +id: GO:0061551 +name: trigeminal ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph] +synonym: "trigeminal ganglia development" RELATED [GOC:dph] +is_a: GO:0061550 ! cranial ganglion development +created_by: dph +creation_date: 2013-07-10T08:42:19Z + +[Term] +id: GO:0061552 +name: ganglion morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph] +synonym: "ganglia morphogenesis" RELATED [GOC:dph] +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0061548 ! ganglion development +created_by: dph +creation_date: 2013-07-10T08:44:57Z + +[Term] +id: GO:0061553 +name: ganglion maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph] +synonym: "ganglia maturation" RELATED [GOC:dph] +is_a: GO:0048799 ! animal organ maturation +relationship: part_of GO:0061548 ! ganglion development +created_by: dph +creation_date: 2013-07-10T08:45:59Z + +[Term] +id: GO:0061554 +name: ganglion formation +namespace: biological_process +def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] +synonym: "ganglia formation" RELATED [GOC:dph] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0061552 ! ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T08:51:50Z + +[Term] +id: GO:0061555 +name: ganglion structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure." [GOC:dph] +synonym: "ganglia structural organization" RELATED [GOC:dph] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0061552 ! ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T08:54:39Z + +[Term] +id: GO:0061556 +name: trigeminal ganglion morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph] +synonym: "trigeminal ganglia morphogenesis" RELATED [GOC:dph] +is_a: GO:0061559 ! cranial ganglion morphogenesis +relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis +relationship: part_of GO:0061551 ! trigeminal ganglion development +created_by: dph +creation_date: 2013-07-10T08:57:12Z + +[Term] +id: GO:0061557 +name: trigeminal ganglion maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph] +synonym: "trigeminal ganglia maturation" RELATED [GOC:dph] +is_a: GO:0061558 ! cranial ganglion maturation +relationship: part_of GO:0021635 ! trigeminal nerve maturation +relationship: part_of GO:0061551 ! trigeminal ganglion development +created_by: dph +creation_date: 2013-07-10T08:58:24Z + +[Term] +id: GO:0061558 +name: cranial ganglion maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph] +synonym: "cranial ganglia maturation" RELATED [GOC:dph] +is_a: GO:0061553 ! ganglion maturation +relationship: part_of GO:0021605 ! cranial nerve maturation +relationship: part_of GO:0061550 ! cranial ganglion development +created_by: dph +creation_date: 2013-07-10T08:59:52Z + +[Term] +id: GO:0061559 +name: cranial ganglion morphogenesis +namespace: biological_process +def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph] +synonym: "cranial ganglia morphogenesis" RELATED [GOC:dph] +is_a: GO:0061552 ! ganglion morphogenesis +relationship: part_of GO:0021602 ! cranial nerve morphogenesis +relationship: part_of GO:0061550 ! cranial ganglion development +created_by: dph +creation_date: 2013-07-10T09:02:15Z + +[Term] +id: GO:0061560 +name: cranial ganglion formation +namespace: biological_process +def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] +synonym: "cranial ganglia formation" RELATED [GOC:dph] +is_a: GO:0061554 ! ganglion formation +relationship: part_of GO:0061559 ! cranial ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T09:07:27Z + +[Term] +id: GO:0061561 +name: trigeminal ganglion formation +namespace: biological_process +def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] +synonym: "trigeminal ganglia formation" RELATED [GOC:dph] +is_a: GO:0061560 ! cranial ganglion formation +relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T09:08:13Z + +[Term] +id: GO:0061562 +name: cranial ganglion structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure." [GOC:dph] +synonym: "cranial ganglia structural organization" RELATED [GOC:dph] +is_a: GO:0061555 ! ganglion structural organization +relationship: part_of GO:0021604 ! cranial nerve structural organization +relationship: part_of GO:0061559 ! cranial ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T09:10:52Z + +[Term] +id: GO:0061563 +name: trigeminal ganglion structural organization +namespace: biological_process +def: "The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure." [GOC:dph] +synonym: "trigeminal ganglia organization" RELATED [GOC:dph] +is_a: GO:0061562 ! cranial ganglion structural organization +relationship: part_of GO:0021637 ! trigeminal nerve structural organization +relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis +created_by: dph +creation_date: 2013-07-10T09:12:11Z + +[Term] +id: GO:0061564 +name: axon development +namespace: biological_process +def: "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." [GOC:dph, GOC:pg, GOC:pr] +is_a: GO:0031175 ! neuron projection development +created_by: dph +creation_date: 2013-07-18T14:43:01Z + +[Term] +id: GO:0061565 +name: dAMP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP." [GOC:dph, PMID:23416111] +is_a: GO:0046940 ! nucleoside monophosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T12:50:38Z + +[Term] +id: GO:0061566 +name: CMP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP." [GOC:dph, PMID:23416111] +is_a: GO:0046940 ! nucleoside monophosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T12:52:39Z + +[Term] +id: GO:0061567 +name: dCMP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP." [GOC:dph, PMID:23416111] +is_a: GO:0046940 ! nucleoside monophosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T12:54:21Z + +[Term] +id: GO:0061568 +name: GDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP." [GOC:dph, PMID:23416111] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T12:57:12Z + +[Term] +id: GO:0061569 +name: UDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP." [GOC:dph, PMID:23416111] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T12:59:32Z + +[Term] +id: GO:0061570 +name: dCDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into dCDP to produce a dCTP." [GOC:dph, PMID:23416111] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T13:02:16Z + +[Term] +id: GO:0061571 +name: TDP phosphorylation +namespace: biological_process +def: "The process of introducing a phosphate group into TDP to produce a TTP." [GOC:dph, PMID:23416111] +is_a: GO:0006165 ! nucleoside diphosphate phosphorylation +created_by: dph +creation_date: 2013-08-01T13:03:34Z + +[Term] +id: GO:0061572 +name: actin filament bundle organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph] +synonym: "actin filament cable organization" RELATED [GOC:dph] +is_a: GO:0007015 ! actin filament organization +created_by: dph +creation_date: 2013-08-02T11:24:11Z + +[Term] +id: GO:0061573 +name: actin filament bundle retrograde transport +namespace: biological_process +def: "A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell." [GOC:dph] +synonym: "actin filament cable retrograde transport" RELATED [GOC:dph] +is_a: GO:0070650 ! actin filament bundle distribution +created_by: dph +creation_date: 2013-08-02T11:31:04Z + +[Term] +id: GO:0061574 +name: ASAP complex +namespace: cellular_component +def: "A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1." [GOC:dph, PMID:12665594, PMID:16314458, PMID:22388736] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2013-10-08T13:09:16Z + +[Term] +id: GO:0061575 +name: cyclin-dependent protein serine/threonine kinase activator activity +namespace: molecular_function +alt_id: GO:0016534 +alt_id: GO:0016535 +def: "Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase." [GOC:dph, PMID:2569363, PMID:3322810] +synonym: "cyclin-dependent protein kinase 5 activator activity" NARROW [] +is_a: GO:0016538 ! cyclin-dependent protein serine/threonine kinase regulator activity +is_a: GO:0043539 ! protein serine/threonine kinase activator activity +relationship: part_of GO:0045737 ! positive regulation of cyclin-dependent protein serine/threonine kinase activity +created_by: dph +creation_date: 2013-10-08T13:50:35Z + +[Term] +id: GO:0061576 +name: acyl-CoA ceramide synthase complex +namespace: cellular_component +def: "A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1." [GOC:dph, PMID:15692566] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2013-10-24T14:42:06Z + +[Term] +id: GO:0061577 +name: calcium ion transmembrane transport via high voltage-gated calcium channel +namespace: biological_process +def: "A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel." [GOC:dph] +synonym: "generation of L-type calcium current" RELATED [] +is_a: GO:0070588 ! calcium ion transmembrane transport +relationship: has_part GO:0008331 ! high voltage-gated calcium channel activity +created_by: dph +creation_date: 2013-11-15T16:20:27Z + +[Term] +id: GO:0061578 +name: Lys63-specific deubiquitinase activity +namespace: molecular_function +def: "Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein." [GOC:dph, GOC:pg, PMID:18313383] +xref: Reactome:R-HSA-5357845 "RIPK1 is deubiquitinated" +xref: Reactome:R-HSA-5690856 "TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1" +xref: Reactome:R-HSA-5691411 "BRCA1-A complex deubiquitinates K63polyUb-histone H2A" +xref: Reactome:R-HSA-5691431 "PSMD14 cleaves K63-linked ubiquitin" +xref: Reactome:R-HSA-5691439 "BRISC complex deubiquitinates NLRP3" +xref: Reactome:R-HSA-5696547 "STAMBPL1 is a deubiquitinase" +xref: Reactome:R-HSA-688136 "TNFAIP3 (A20) deubiquitinates RIP2" +xref: Reactome:R-HSA-741411 "CYLD deubiquitinates NEMO" +xref: Reactome:R-HSA-8869506 "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6" +xref: Reactome:R-HSA-936381 "OTUD5 deubiquitinates TRAF3" +xref: Reactome:R-HSA-936390 "CYLD mediated deubiquitination of DDX58 (RIG-I)" +is_a: GO:0101005 ! ubiquitinyl hydrolase activity +relationship: part_of GO:0070536 ! protein K63-linked deubiquitination +created_by: dph +creation_date: 2013-11-15T19:13:12Z + +[Term] +id: GO:0061579 +name: N-acyl homoserine lactone synthase activity +namespace: molecular_function +def: "Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone." [GOC:dph] +synonym: "autoinducer-1 synthase" RELATED [GOC:dph] +xref: EC:2.3.1.184 +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dph +creation_date: 2013-11-15T19:48:23Z + +[Term] +id: GO:0061580 +name: colon epithelial cell migration +namespace: biological_process +def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] +is_a: GO:0061582 ! intestinal epithelial cell migration +created_by: dph +creation_date: 2013-12-23T07:26:54Z + +[Term] +id: GO:0061581 +name: corneal epithelial cell migration +namespace: biological_process +def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] +is_a: GO:0010631 ! epithelial cell migration +created_by: dph +creation_date: 2013-12-23T07:28:29Z + +[Term] +id: GO:0061582 +name: intestinal epithelial cell migration +namespace: biological_process +def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] +is_a: GO:0010631 ! epithelial cell migration +created_by: dph +creation_date: 2013-12-23T07:30:55Z + +[Term] +id: GO:0061583 +name: colon epithelial cell chemotaxis +namespace: biological_process +def: "The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [GOC:dph] +is_a: GO:0060326 ! cell chemotaxis +is_a: GO:0061580 ! colon epithelial cell migration +created_by: dph +creation_date: 2013-12-23T07:46:57Z + +[Term] +id: GO:0061584 +name: hypocretin secretion +namespace: biological_process +def: "The controlled release of hypocretin from a cell or a tissue." [GOC:dph] +synonym: "orexin secretion" EXACT [GOC:dph] +is_a: GO:0002790 ! peptide secretion +created_by: dph +creation_date: 2013-12-26T10:07:38Z + +[Term] +id: GO:0061585 +name: hypocretin secretion, neurotransmission +namespace: biological_process +def: "The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter." [GOC:dph] +synonym: "orexin secretion, neurotransmission" EXACT [GOC:dph] +is_a: GO:0061544 ! peptide secretion, neurotransmission +is_a: GO:0061584 ! hypocretin secretion +created_by: dph +creation_date: 2013-12-26T10:09:37Z + +[Term] +id: GO:0061586 +name: positive regulation of transcription by transcription factor localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor." [GOC:dph] +is_a: GO:0034613 ! cellular protein localization +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +created_by: dph +creation_date: 2014-01-31T08:43:43Z + +[Term] +id: GO:0061587 +name: transfer RNA gene-mediated silencing +namespace: biological_process +def: "The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes." [GOC:dph, PMID:23707796] +synonym: "tgm silencing" EXACT [PMID:23707796] +synonym: "transfer RNA gene-mediated chromatin silencing" EXACT [GOC:dph] +synonym: "transfer RNA gene-mediated gene silencing" EXACT [GOC:dph] +synonym: "tRNA gene-mediated chromatin silencing" EXACT [GOC:dph] +synonym: "tRNA gene-mediated gene silencing" EXACT [GOC:dph] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0006342 ! chromatin silencing +created_by: dph +creation_date: 2014-02-05T09:03:59Z + +[Term] +id: GO:0061588 +name: calcium activated phospholipid scrambling +namespace: biological_process +def: "The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839] +is_a: GO:0017121 ! plasma membrane phospholipid scrambling +created_by: dph +creation_date: 2014-02-05T15:14:34Z + +[Term] +id: GO:0061589 +name: calcium activated phosphatidylserine scrambling +namespace: biological_process +def: "The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839] +is_a: GO:0061588 ! calcium activated phospholipid scrambling +created_by: dph +creation_date: 2014-02-05T15:17:21Z + +[Term] +id: GO:0061590 +name: calcium activated phosphatidylcholine scrambling +namespace: biological_process +def: "The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839] +is_a: GO:0061588 ! calcium activated phospholipid scrambling +created_by: dph +creation_date: 2014-02-05T15:23:03Z + +[Term] +id: GO:0061591 +name: calcium activated galactosylceramide scrambling +namespace: biological_process +def: "The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus." [GOC:krc, PMID:23532839] +is_a: GO:0061588 ! calcium activated phospholipid scrambling +created_by: dph +creation_date: 2014-02-05T15:25:52Z + +[Term] +id: GO:0061592 +name: phosphatidylserine exposure on osteoblast involved in bone mineralization +namespace: biological_process +def: "A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization." [GOC:krc, PMID:22936354] +is_a: GO:0017121 ! plasma membrane phospholipid scrambling +relationship: part_of GO:0030282 ! bone mineralization +created_by: dph +creation_date: 2014-02-05T15:27:39Z + +[Term] +id: GO:0061593 +name: sulfoquinovose isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose." [GOC:dph, PMID:24463506] +is_a: GO:0016853 ! isomerase activity +created_by: dph +creation_date: 2014-02-10T09:56:04Z + +[Term] +id: GO:0061594 +name: 6-deoxy-6-sulfofructose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP." [PMID:24463506] +xref: EC:2.7.1.184 +xref: MetaCyc:RXN-15297 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +created_by: dph +creation_date: 2014-02-10T09:59:26Z + +[Term] +id: GO:0061595 +name: 6-deoxy-6-sulfofructose-1-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate." [PMID:24463506] +is_a: GO:0016832 ! aldehyde-lyase activity +created_by: dph +creation_date: 2014-02-10T10:05:27Z + +[Term] +id: GO:0061596 +name: 3-sulfolactaldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+." [EC:1.1.1.373, GOC:dph, PMID:24463506] +xref: EC:1.1.1.373 +xref: MetaCyc:RXN-15299 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: dph +creation_date: 2014-02-10T10:09:43Z + +[Term] +id: GO:0061597 +name: obsolete cyclic pyranopterin monophosphate synthase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate." [EC:4.1.99.18, GOC:dph, PMID:18154309] +comment: This term was made obsolete because it represents two distinct molecular functions. +is_obsolete: true +created_by: dph +creation_date: 2014-02-10T13:54:19Z + +[Term] +id: GO:0061598 +name: molybdopterin adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin." [EC:2.7.7.75, GOC:dph] +xref: EC:2.7.7.75 +xref: RHEA:31331 +is_a: GO:0070566 ! adenylyltransferase activity +created_by: dph +creation_date: 2014-02-10T14:14:06Z + +[Term] +id: GO:0061599 +name: molybdopterin molybdotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP." [EC:2.10.1.1, GOC:dph] +xref: EC:2.10.1.1 +xref: Reactome:R-HSA-947531 "Molybdenum ion transfer onto molybdopterin" +is_a: GO:0016740 ! transferase activity +created_by: dph +creation_date: 2014-02-10T14:30:31Z + +[Term] +id: GO:0061602 +name: molybdenum cofactor cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor." [EC:2.7.7.76, GOC:dph] +xref: EC:2.7.7.76 +is_a: GO:0070567 ! cytidylyltransferase activity +created_by: dph +creation_date: 2014-02-10T14:46:38Z + +[Term] +id: GO:0061603 +name: molybdenum cofactor guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor." [EC:2.7.7.77, GOC:dph] +xref: EC:2.7.7.77 +is_a: GO:0070568 ! guanylyltransferase activity +created_by: dph +creation_date: 2014-02-10T14:54:36Z + +[Term] +id: GO:0061604 +name: molybdopterin-synthase sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase." [EC:2.8.1.11, GOC:dph, PMID:18154309, PMID:22370186] +xref: EC:2.8.1.11 +is_a: GO:0016783 ! sulfurtransferase activity +created_by: dph +creation_date: 2014-02-11T11:56:16Z + +[Term] +id: GO:0061605 +name: molybdopterin-synthase adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP." [EC:2.7.7.80, GOC:dph, PMID:18154309, PMID:22370186] +xref: EC:2.7.7.80 +is_a: GO:0070566 ! adenylyltransferase activity +created_by: dph +creation_date: 2014-02-11T12:01:32Z + +[Term] +id: GO:0061606 +name: N-terminal protein amino acid propionylation +namespace: biological_process +def: "The propionylation of the N-terminal amino acid of proteins." [GOC:dph, PMID:17267393, PMID:23043182] +is_a: GO:0043687 ! post-translational protein modification +created_by: dph +creation_date: 2014-02-11T14:13:05Z + +[Term] +id: GO:0061607 +name: peptide alpha-N-propionyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein." [GOC:dph, PMID:23043182] +synonym: "N-terminal propionyltransferase activity" EXACT [PMID:23043182] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0061606 ! N-terminal protein amino acid propionylation +created_by: dph +creation_date: 2014-02-11T14:24:35Z + +[Term] +id: GO:0061608 +name: nuclear import signal receptor activity +namespace: molecular_function +def: "Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein." [GOC:dph, GOC:pg, GOC:vw, PMID:28713609, Wikipedia:Nuclear_transport] +synonym: "importin activity" RELATED [] +is_a: GO:0140142 ! nucleocytoplasmic carrier activity +intersection_of: GO:0140142 ! nucleocytoplasmic carrier activity +intersection_of: part_of GO:0051170 ! import into nucleus +relationship: part_of GO:0051170 ! import into nucleus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14336 xsd:anyURI +created_by: dph +creation_date: 2014-03-03T07:58:18Z + +[Term] +id: GO:0061609 +name: fructose-1-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde." [GOC:dph, GOC:glycolysis, ISBN:0201090910, RHEA:30851] +xref: Reactome:R-HSA-5656438 "Defective ALDOB does not cleave Fru 1-P to GA and DHAP" +xref: Reactome:R-HSA-70342 "ALDOB tetramer cleaves Fru-1-P to GA and DHAP" +xref: RHEA:30851 +is_a: GO:0016832 ! aldehyde-lyase activity +created_by: dph +creation_date: 2014-03-28T08:54:24Z + +[Term] +id: GO:0061610 +name: glycerol to glycerone phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate." [GOC:dph, ISBN:0201090910] +synonym: "glycerol metabolism to DHAP" EXACT [GOC:dph] +synonym: "glycerol metabolism to dihydroxyacetone phosphate" EXACT [GOC:dph] +synonym: "glycerol metabolism to glycerone phosphate" EXACT [GOC:dph] +synonym: "glycerol to DHAP metabolic process" EXACT [GOC:dph] +synonym: "glycerol to dihydroxyacetone phosphate metabolic process" EXACT [GOC:dph] +is_a: GO:0006071 ! glycerol metabolic process +relationship: has_part GO:0004367 ! glycerol-3-phosphate dehydrogenase [NAD+] activity +created_by: dph +creation_date: 2014-04-03T13:26:21Z + +[Term] +id: GO:0061611 +name: mannose to fructose-6-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +synonym: "mannose metabolism to fructose-6-phosphate" EXACT [GOC:dph] +is_a: GO:0006013 ! mannose metabolic process +created_by: dph +creation_date: 2014-04-03T13:38:50Z + +[Term] +id: GO:0061612 +name: galactose to glucose-1-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +is_a: GO:0006012 ! galactose metabolic process +relationship: has_part GO:0003978 ! UDP-glucose 4-epimerase activity +created_by: dph +creation_date: 2014-04-04T08:18:49Z + +[Term] +id: GO:0061613 +name: glycolytic process from glycerol +namespace: biological_process +def: "The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH." [GOC:dph, ISBN:0201090910] +is_a: GO:0006096 ! glycolytic process +is_a: GO:0019563 ! glycerol catabolic process +relationship: has_part GO:0004807 ! triose-phosphate isomerase activity +created_by: dph +creation_date: 2014-04-04T08:26:57Z + +[Term] +id: GO:0061614 +name: pri-miRNA transcription by RNA polymerase II +namespace: biological_process +def: "The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation." [GOC:dph, GOC:kmv, PMID:18778799] +synonym: "pri-miRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006366 ! transcription by RNA polymerase II +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: dph +creation_date: 2014-04-08T08:42:54Z + +[Term] +id: GO:0061615 +name: glycolytic process through fructose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +synonym: "glycolysis through fructose-6-phosphate" EXACT [GOC:dph] +xref: MetaCyc:PWY-5484 +is_a: GO:0006096 ! glycolytic process +intersection_of: GO:0006096 ! glycolytic process +intersection_of: has_part GO:0003872 ! 6-phosphofructokinase activity +intersection_of: has_part GO:0004332 ! fructose-bisphosphate aldolase activity +intersection_of: has_part GO:0004807 ! triose-phosphate isomerase activity +relationship: has_part GO:0003872 ! 6-phosphofructokinase activity +relationship: has_part GO:0004332 ! fructose-bisphosphate aldolase activity +relationship: has_part GO:0004807 ! triose-phosphate isomerase activity +created_by: dph +creation_date: 2014-04-08T10:08:49Z + +[Term] +id: GO:0061616 +name: glycolytic process from fructose through fructose-6-phosphate +namespace: biological_process +def: "The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +synonym: "glycolysis from fructose through fructose-6-phosphate" EXACT [GOC:dph] +xref: MetaCyc:PWY-5484 +is_a: GO:0006001 ! fructose catabolic process +is_a: GO:0061615 ! glycolytic process through fructose-6-phosphate +created_by: dph +creation_date: 2014-04-08T10:20:37Z + +[Term] +id: GO:0061617 +name: MICOS complex +namespace: cellular_component +def: "Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60." [GOC:dph, PMID:21944719, PMID:21987634, PMID:22009199, PMID:24687277] +synonym: "Fcj1 complex" EXACT [GOC:dph] +synonym: "MINOS complex" EXACT [GOC:dph] +synonym: "mitochondrial contact site and cristae organizing system" EXACT [GOC:dph] +synonym: "MitOS complex" EXACT [GOC:dph] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +relationship: part_of GO:0031305 ! integral component of mitochondrial inner membrane +created_by: dph +creation_date: 2014-04-14T07:18:13Z + +[Term] +id: GO:0061618 +name: obsolete sublamina densa +namespace: cellular_component +def: "OBSOLETE. The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers." [GOC:BHF, PMID:15623520] +comment: This term was made obsolete because it is thought to be an experimental artefact. +is_obsolete: true +created_by: dph +creation_date: 2014-04-14T08:43:13Z + +[Term] +id: GO:0061619 +name: glycolytic process from mannose through fructose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +is_a: GO:0019309 ! mannose catabolic process +is_a: GO:0061615 ! glycolytic process through fructose-6-phosphate +created_by: dph +creation_date: 2014-04-14T09:13:13Z + +[Term] +id: GO:0061620 +name: glycolytic process through glucose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +xref: MetaCyc:GLYCOLYSIS +is_a: GO:0061615 ! glycolytic process through fructose-6-phosphate +relationship: has_part GO:0004347 ! glucose-6-phosphate isomerase activity +created_by: dph +creation_date: 2014-04-14T09:17:48Z + +[Term] +id: GO:0061621 +name: canonical glycolysis +namespace: biological_process +def: "The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910, ISBN:0879010479] +xref: MetaCyc:ANAGLYCOLYSIS-PWY +xref: MetaCyc:PWY66-400 +xref: Reactome:R-HSA-70171 "Glycolysis, Homo sapiens" +xref: Wikipedia:Glycolysis +is_a: GO:0006735 ! NADH regeneration +is_a: GO:0061620 ! glycolytic process through glucose-6-phosphate +is_a: GO:0061718 ! glucose catabolic process to pyruvate +relationship: has_part GO:0004365 ! glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity +created_by: dph +creation_date: 2014-04-14T09:21:54Z + +[Term] +id: GO:0061622 +name: glycolytic process through glucose-1-phosphate +namespace: biological_process +def: "The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910] +is_a: GO:0061620 ! glycolytic process through glucose-6-phosphate +intersection_of: GO:0061620 ! glycolytic process through glucose-6-phosphate +intersection_of: has_part GO:0004614 ! phosphoglucomutase activity +relationship: has_part GO:0004614 ! phosphoglucomutase activity +created_by: dph +creation_date: 2014-04-28T08:08:01Z + +[Term] +id: GO:0061623 +name: glycolytic process from galactose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP." [GOC:dph, ISBN:0201090910] +is_a: GO:0019388 ! galactose catabolic process +is_a: GO:0061622 ! glycolytic process through glucose-1-phosphate +created_by: dph +creation_date: 2014-04-28T08:13:38Z + +[Term] +id: GO:0061624 +name: fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate." [GOC:dph, ISBN:0201090910] +is_a: GO:0006001 ! fructose catabolic process +is_a: GO:0019682 ! glyceraldehyde-3-phosphate metabolic process +relationship: has_part GO:0050354 ! triokinase activity +relationship: has_part GO:0061609 ! fructose-1-phosphate aldolase activity +created_by: dph +creation_date: 2014-04-29T12:58:28Z + +[Term] +id: GO:0061625 +name: glycolytic process through fructose-1-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH." [GOC:dph, ISBN:0201090910] +is_a: GO:0006001 ! fructose catabolic process +is_a: GO:0006096 ! glycolytic process +relationship: has_part GO:0004807 ! triose-phosphate isomerase activity +created_by: dph +creation_date: 2014-04-29T13:04:10Z + +[Term] +id: GO:0061626 +name: pharyngeal arch artery morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914] +synonym: "aortic arch artery morphogenesis" BROAD [GOC:dph] +is_a: GO:0048844 ! artery morphogenesis +relationship: part_of GO:0060037 ! pharyngeal system development +created_by: dph +creation_date: 2014-05-09T15:34:06Z + +[Term] +id: GO:0061627 +name: S-methylmethionine-homocysteine S-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+." [EC:2.1.1.10, GOC:BHF, GOC:dph] +synonym: "homocysteine methyltransferase activity" RELATED [EC:2.1.1.10] +synonym: "homocysteine transmethylase activity" RELATED [EC:2.1.1.10] +synonym: "methylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] +synonym: "S-methylmethionine homocysteine transmethylase activity" EXACT [EC:2.1.1.10] +xref: Reactome:R-HSA-5696838 "BHMT2 tetramer transfers CH3 group from SMM to LHCYS" +xref: RHEA:26337 +is_a: GO:0008172 ! S-methyltransferase activity +created_by: dph +creation_date: 2014-05-14T14:32:02Z + +[Term] +id: GO:0061628 +name: H3K27me3 modified histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 27 has been modified by trimethylation." [GOC:dph, PMID:23948251] +synonym: "H3-K27me3 modified histone binding" EXACT [GOC:dph] +is_a: GO:0035064 ! methylated histone binding +created_by: dph +creation_date: 2014-05-14T15:36:53Z + +[Term] +id: GO:0061629 +name: RNA polymerase II-specific DNA-binding transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription." [GOC:dph, GOC:vw] +synonym: "RNA polymerase II sequence-specific DNA binding transcription factor binding" EXACT [] +synonym: "RNA polymerase II sequence-specific DNA-binding transcription factor binding" EXACT [] +is_a: GO:0140297 ! DNA-binding transcription factor binding +created_by: dph +creation_date: 2014-05-15T09:12:24Z + +[Term] +id: GO:0061630 +name: ubiquitin protein ligase activity +namespace: molecular_function +alt_id: GO:0090302 +alt_id: GO:0090622 +alt_id: GO:1904264 +alt_id: GO:1904822 +def: "Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues." [GOC:BioGRID, GOC:dph, GOC:mah, GOC:tb, PMID:22863777] +comment: This enzyme catalyzes a transferase reaction. +synonym: "APC-Cdc20 complex activity" NARROW [GOC:vw] +synonym: "APC-fizzy related complex activity" NARROW [GOC:vw] +synonym: "E3" RELATED [GOC:dph] +synonym: "E3 involved in endoplasmic reticulum-associated degradation" NARROW [GOC:TermGenie] +synonym: "ER-associated E3 ligase" RELATED [PMID:24019521] +synonym: "protein ubiquitination activity" EXACT [GOC:dph] +synonym: "ubiquitin ligase activity" EXACT [GOC:dph] +synonym: "ubiquitin ligase activity involved in ER-associated degradation pathway" NARROW [GOC:TermGenie] +synonym: "ubiquitin protein ligase activity involved in chloroplast disassembly" NARROW [] +synonym: "ubiquitin protein ligase activity involved in ER-associated degradation pathway" NARROW [GOC:TermGenie] +synonym: "ubiquitin protein ligase activity involved in ERAD pathway" NARROW [] +synonym: "ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition" NARROW [GOC:dph, GOC:mah, GOC:tb] +xref: Reactome:R-HSA-1225956 "Inefficient ubiquitination of ligand-responsive p-6Y-EGFR mutants by p-Y371-CBL" +xref: Reactome:R-HSA-1504190 "DVL is ubiquitinated by CUL3:KLHL12:RBX1" +xref: Reactome:R-HSA-201445 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8" +xref: Reactome:R-HSA-3322429 "XIAP monoubiquinates TLE" +xref: Reactome:R-HSA-3640861 "RNF146 ubiquitinates ADP-ribosylated AXIN" +xref: Reactome:R-HSA-4608852 "SMURF1/2 ubiquitinates PRICKLE1" +xref: Reactome:R-HSA-4641129 "AXIN is ubiquitinated by SMURF2" +xref: Reactome:R-HSA-4641159 "DVL1 is ubiquitinated by HECW1" +xref: Reactome:R-HSA-4641246 "ZNRF3 autoubiquitinates to promote its internalization" +xref: Reactome:R-HSA-4641253 "ZNRF3 ubiquitinates FZD to promote its downregulation" +xref: Reactome:R-HSA-5246693 "APC is K63-polyubiquitinated" +xref: Reactome:R-HSA-5610737 "NUMB:ITCH bind and ubiquitnate GLI1" +xref: Reactome:R-HSA-5632648 "SMURF1/2 ubiquitinates PTCH1" +xref: Reactome:R-HSA-5635856 "SPOP:CUL3:RBX1 ubiquitinates GLI2,3" +xref: Reactome:R-HSA-5635864 "NUMB:ITCH ubiquitinates GLI1" +xref: Reactome:R-HSA-5654672 "CBL ubiquitinates FRS2 and FGFR1" +xref: Reactome:R-HSA-5654677 "CBL ubiquitinates FRS2 and FGFR2" +xref: Reactome:R-HSA-5654679 "CBL ubiquitinates FRS2 and FGFR3" +xref: Reactome:R-HSA-5654684 "CBL ubiquitinates FRS2 and FGFR4" +xref: Reactome:R-HSA-5658424 "KBTBD7:CUL3:RBX1 ubiquitinates NF1" +xref: Reactome:R-HSA-5674022 "BRAP autoubiquitinates" +xref: Reactome:R-HSA-5682858 "RNF8 and RNF168 ubiquitinate H2AFX" +xref: Reactome:R-HSA-5684071 "RNF4 ubiquitinates MDC1" +xref: Reactome:R-HSA-5687081 "MAPK6 is ubiquitinated at the N-terminal" +xref: Reactome:R-HSA-5689111 "PARK2 autoubiquitinates" +xref: Reactome:R-HSA-5690827 "TNFAIP3 (A20) ubiquitinates RIPK1" +xref: Reactome:R-HSA-6781867 "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II" +xref: Reactome:R-HSA-6782943 "UV-DDB ubiquitinates XPC" +xref: Reactome:R-HSA-6785361 "Monoubiquitination of FANCD2:FANCI" +xref: Reactome:R-HSA-6790487 "RNF111 ubiquitinates SUMOylated XPC" +xref: Reactome:R-HSA-6798373 "MDM2 ubiquitinates DYRK2" +xref: Reactome:R-HSA-6804253 "MDM2 ubiquitinates JMY" +xref: Reactome:R-HSA-6804441 "RNF34 or RFFL ubiquitinates phosphorylated TP53" +xref: Reactome:R-HSA-6804724 "MDM2 ubiquitinates phosphorylated MDM4" +xref: Reactome:R-HSA-6804879 "MDM2 ubiquitinates TP53" +xref: Reactome:R-HSA-6804942 "MDM2 homodimers auto-ubiquitinate" +xref: Reactome:R-HSA-6807106 "PTEN undergoes monoubiquitination" +xref: Reactome:R-HSA-6807134 "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN" +xref: Reactome:R-HSA-68946 "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin" +xref: Reactome:R-HSA-69015 "Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex" +xref: Reactome:R-HSA-8848829 "CBL autoubiquitinates" +xref: Reactome:R-HSA-8851011 "TRIM27 polyubiquitinates PTEN" +xref: Reactome:R-HSA-8854041 "SCF-FBXL7 ubiquitinates AURKA" +xref: Reactome:R-HSA-8854051 "SCF-FBXL18 ubiquitinates FBXL7" +xref: Reactome:R-HSA-8854628 "MYLIP dimer ubiquitinates VLDLR on Lys-839" +xref: Reactome:R-HSA-8866546 "RNF5 and RNF185 ubiquitinate misfolded CFTR" +xref: Reactome:R-HSA-8866856 "RNF5 and RNF185 ubiquitinate CFTR F508del" +xref: Reactome:R-HSA-8867288 "OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5" +xref: Reactome:R-HSA-8875183 "CBL monoubiquitinates activated MET" +xref: Reactome:R-HSA-8875431 "LRIG1 undergoes ubiquitination" +xref: Reactome:R-HSA-8876258 "CBL monoubiquitinates InlB-bound MET" +xref: Reactome:R-HSA-8877003 "CBLL1 ubiqutinates the InlA-bound CDH1 complex" +xref: Reactome:R-HSA-8938773 "RNF144A polyubiquitinates PRKDC" +xref: Reactome:R-HSA-8938815 "RNF152 polyubiquitinates RRAGA" +xref: Reactome:R-HSA-8939335 "RNF181 polyubiquinates BCL10" +xref: Reactome:R-HSA-8939706 "SCF(SKP2) polyubiquitinates RUNX2" +xref: Reactome:R-HSA-8942101 "RNF20:RNF40 monoubiquitinates Histone H2B" +xref: Reactome:R-HSA-8943003 "SHPRH polyubiquitinates monoubiquitinated PCNA" +xref: Reactome:R-HSA-8943040 "HLTF polyubiquitinates monoubiquitinated PCNA" +xref: Reactome:R-HSA-8943080 "TMEM129 polyubiquitinates HLA (MHC class I heavy chain) bound to cytomegalovirus US11" +xref: Reactome:R-HSA-8948775 "MKRN1 polyubiquitinates PTEN" +xref: Reactome:R-HSA-8948832 "RNF146 polyubiquitinates PARylated PTEN" +xref: Reactome:R-HSA-8952382 "MDM2 polyubiquitinates RUNX3" +xref: Reactome:R-HSA-8952419 "SMURFs ubiquitinate RUNX3" +xref: Reactome:R-HSA-8953946 "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11" +xref: Reactome:R-HSA-8956026 "CUL9:RBX1 ubiquitinates BIRC5" +xref: Reactome:R-HSA-8956684 "ITCH polyubiquitinates TP73" +xref: Reactome:R-HSA-9008076 "WWP1 polyubiquitinates RUNX2" +xref: Reactome:R-HSA-9008479 "FBXW7 polyubiquitinates RUNX2" +xref: Reactome:R-HSA-9009308 "STUB1 polyubiquitinates RUNX2" +xref: Reactome:R-HSA-9009403 "SMURF1 polyubiquitinates RUNX2" +xref: Reactome:R-HSA-9011300 "ZSWIM8 ubiquitinates ROBO3.1" +xref: Reactome:R-HSA-9021523 "WWP2 ubiquitinates NOTCH3" +xref: Reactome:R-HSA-9033485 "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11" +xref: Reactome:R-HSA-934604 "Phosphorylated SPRY2 is ubiquitinated by CBL" +xref: Reactome:R-HSA-936462 "PIN1 mediated IRF3 degradation" +xref: Reactome:R-HSA-936475 "Negative regulation of DDX58/IFIH1 signaling by RNF216" +xref: Reactome:R-HSA-9604629 "FBXW7 promotes ubiquitination of p-NICD4" +xref: Reactome:R-HSA-990526 "Recruitment of AIP4 and K48 ubiquitination of MAVS/IPS-1" +is_a: GO:0004842 ! ubiquitin-protein transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-05-18T09:11:21Z + +[Term] +id: GO:0061631 +name: ubiquitin conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue." [GOC:BioGRID, GOC:dph] +synonym: "E2" RELATED [GOC:dph] +synonym: "HECT E3" RELATED [GOC:dph] +xref: EC:2.3.2.23 +is_a: GO:0004842 ! ubiquitin-protein transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-05-18T09:25:19Z + +[Term] +id: GO:0061632 +name: RNA lariat debranching enzyme activator activity +namespace: molecular_function +def: "Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide." [GOC:dph, PMID:24919400] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0008419 ! RNA lariat debranching enzyme activity +created_by: dph +creation_date: 2014-06-17T10:07:31Z + +[Term] +id: GO:0061633 +name: transport-coupled glycolytic process through glucose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport." [GOC:dph] +is_a: GO:0061620 ! glycolytic process through glucose-6-phosphate +is_a: GO:0061718 ! glucose catabolic process to pyruvate +created_by: dph +creation_date: 2014-06-19T09:12:37Z + +[Term] +id: GO:0061634 +name: alpha-D-xyloside xylohydrolase +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose." [EC:3.2.1.177] +synonym: "alpha-xylosidase" EXACT [EC:3.2.1.177] +xref: EC:3.2.1.177 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: dph +creation_date: 2014-07-28T08:12:39Z + +[Term] +id: GO:0061635 +name: regulation of protein complex stability +namespace: biological_process +def: "Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly." [GOC:dph] +is_a: GO:0065008 ! regulation of biological quality +created_by: dph +creation_date: 2014-08-13T14:40:21Z + +[Term] +id: GO:0061638 +name: CENP-A containing chromatin +namespace: cellular_component +def: "The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment." [GOC:vw, PMID:20206496, PMID:22729156] +synonym: "centromeric core domain chromatin" RELATED [GOC:vw] +synonym: "centromeric core region chromatin" EXACT [GOC:vw] +is_a: GO:0000785 ! chromatin +relationship: part_of GO:0034506 ! chromosome, centromeric core domain +created_by: dph +creation_date: 2014-08-20T14:06:35Z + +[Term] +id: GO:0061639 +name: Cdv-dependent cytokinesis +namespace: biological_process +def: "A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells." [GOC:dph, PMID:18987308] +is_a: GO:0000910 ! cytokinesis +created_by: dph +creation_date: 2014-08-21T14:55:04Z + +[Term] +id: GO:0061640 +name: cytoskeleton-dependent cytokinesis +namespace: biological_process +def: "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." [GOC:dph] +is_a: GO:0000910 ! cytokinesis +created_by: dph +creation_date: 2014-08-22T14:21:35Z + +[Term] +id: GO:0061641 +name: CENP-A containing chromatin organization +namespace: biological_process +def: "Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin." [GOC:dph] +synonym: "centromeric chromatin organization" RELATED [GOC:dph] +is_a: GO:0006325 ! chromatin organization +created_by: dph +creation_date: 2014-08-27T12:26:14Z + +[Term] +id: GO:0061642 +name: chemoattraction of axon +namespace: biological_process +def: "The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal." [GOC:dph, GOC:krc] +is_a: GO:0050918 ! positive chemotaxis +intersection_of: GO:0050918 ! positive chemotaxis +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0070887 ! cellular response to chemical stimulus +created_by: dph +creation_date: 2014-08-29T08:21:24Z + +[Term] +id: GO:0061643 +name: chemorepulsion of axon +namespace: biological_process +def: "The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." [GOC:dph, GOC:krc] +is_a: GO:0050919 ! negative chemotaxis +intersection_of: GO:0050919 ! negative chemotaxis +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0070887 ! cellular response to chemical stimulus +created_by: dph +creation_date: 2014-08-29T08:35:40Z + +[Term] +id: GO:0061644 +name: protein localization to CENP-A containing chromatin +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin." [GOC:dph, GOC:vw] +is_a: GO:0071168 ! protein localization to chromatin +is_a: GO:0071459 ! protein localization to chromosome, centromeric region +created_by: dph +creation_date: 2014-08-29T12:17:05Z + +[Term] +id: GO:0061645 +name: endocytic patch +namespace: cellular_component +def: "The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle." [GOC:dph, PMID:22949647] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005938 ! cell cortex +created_by: dph +creation_date: 2014-09-02T09:23:38Z + +[Term] +id: GO:0061646 +name: positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter." [GOC:pad, GOC:PARL] +is_a: GO:0051716 ! cellular response to stimulus +is_a: GO:1903296 ! positive regulation of glutamate secretion, neurotransmission +created_by: dph +creation_date: 2014-10-02T14:18:49Z + +[Term] +id: GO:0061647 +name: histone H3-K9 modification +namespace: biological_process +def: "The modification of histone H3 at a lysine in position 9 of the histone." [GOC:vw] +is_a: GO:0016570 ! histone modification +created_by: dph +creation_date: 2014-10-02T15:07:42Z + +[Term] +id: GO:0061648 +name: tooth replacement +namespace: biological_process +def: "The process whose specific outcome is the replacement of an existing tooth with another tooth." [GOC:dph, PMID:15170864] +is_a: GO:0042476 ! odontogenesis +created_by: dph +creation_date: 2014-10-02T15:26:53Z + +[Term] +id: GO:0061649 +name: ubiquitin modification-dependent histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:dph, PMID:24526689] +synonym: "ubiquitinated histone binding" RELATED [] +is_a: GO:0042393 ! histone binding +is_a: GO:0140036 ! ubiquitin-dependent protein binding +created_by: dph +creation_date: 2014-11-04T10:21:04Z + +[Term] +id: GO:0061650 +name: ubiquitin-like protein conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [] +synonym: "small conjugating protein conjugating enzyme activity" EXACT [GOC:dph] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +created_by: dph +creation_date: 2014-11-06T13:15:27Z + +[Term] +id: GO:0061651 +name: Atg12 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0019777 ! Atg12 transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:17:36Z + +[Term] +id: GO:0061652 +name: FAT10 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0019775 ! FAT10 transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:21:50Z + +[Term] +id: GO:0061653 +name: ISG15 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0042296 ! ISG15 transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:24:50Z + +[Term] +id: GO:0061654 +name: NEDD8 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0019788 ! NEDD8 transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:27:56Z + +[Term] +id: GO:0061655 +name: Pup conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +is_a: GO:0072496 ! Pup transferase activity +created_by: dph +creation_date: 2014-11-06T13:30:46Z + +[Term] +id: GO:0061656 +name: SUMO conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0019789 ! SUMO transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:33:20Z + +[Term] +id: GO:0061657 +name: UFM1 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +is_a: GO:0071568 ! UFM1 transferase activity +created_by: dph +creation_date: 2014-11-06T13:35:13Z + +[Term] +id: GO:0061658 +name: URM1 conjugating enzyme activity +namespace: molecular_function +def: "Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue." [GOC:dph] +synonym: "E2" RELATED [GOC:dph] +is_a: GO:0042294 ! URM1 transferase activity +is_a: GO:0061650 ! ubiquitin-like protein conjugating enzyme activity +created_by: dph +creation_date: 2014-11-06T13:37:26Z + +[Term] +id: GO:0061659 +name: ubiquitin-like protein ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +synonym: "small conjugating protein ligase activity" EXACT [GOC:dph] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +created_by: dph +creation_date: 2014-11-06T13:46:23Z + +[Term] +id: GO:0061660 +name: Atg12 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0019777 ! Atg12 transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T13:50:42Z + +[Term] +id: GO:0061661 +name: FAT10 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0019775 ! FAT10 transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T13:53:10Z + +[Term] +id: GO:0061662 +name: ISG15 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0042296 ! ISG15 transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T13:54:48Z + +[Term] +id: GO:0061663 +name: NEDD8 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0019788 ! NEDD8 transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T13:57:00Z + +[Term] +id: GO:0061664 +name: Pup ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +is_a: GO:0072496 ! Pup transferase activity +created_by: dph +creation_date: 2014-11-06T13:59:09Z + +[Term] +id: GO:0061665 +name: SUMO ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0019789 ! SUMO transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T14:00:44Z + +[Term] +id: GO:0061666 +name: UFM1 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +is_a: GO:0071568 ! UFM1 transferase activity +created_by: dph +creation_date: 2014-11-06T14:02:37Z + +[Term] +id: GO:0061667 +name: URM1 ligase activity +namespace: molecular_function +def: "Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph] +synonym: "E3" RELATED [GOC:dph] +is_a: GO:0042294 ! URM1 transferase activity +is_a: GO:0061659 ! ubiquitin-like protein ligase activity +created_by: dph +creation_date: 2014-11-06T14:04:43Z + +[Term] +id: GO:0061668 +name: mitochondrial ribosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits." [GOC:dph] +is_a: GO:0042255 ! ribosome assembly +created_by: dph +creation_date: 2014-11-07T15:32:20Z + +[Term] +id: GO:0061669 +name: spontaneous neurotransmitter secretion +namespace: biological_process +def: "Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential." [GOC:dph, GOC:pad, GOC:PARL, PMID:21334193] +synonym: "stimulus-independent neurotransmitter secretion" EXACT [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +relationship: part_of GO:0098814 ! spontaneous synaptic transmission +created_by: dph +creation_date: 2014-11-17T07:52:35Z + +[Term] +id: GO:0061670 +name: evoked neurotransmitter secretion +namespace: biological_process +def: "Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential." [GOC:dph, GOC:pad, GOC:PARL, PMID:21334193] +synonym: "stimulus-dependant neurotransmitter secretion" EXACT [GOC:dph] +is_a: GO:0007269 ! neurotransmitter secretion +created_by: dph +creation_date: 2014-11-17T08:06:21Z + +[Term] +id: GO:0061671 +name: Cbp3p-Cbp6 complex +namespace: cellular_component +def: "A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly." [GOC:dph, GOC:rb, PMID:21670217] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2014-11-18T15:08:30Z + +[Term] +id: GO:0061672 +name: glutathione hydrolase complex +namespace: cellular_component +def: "Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly." [GOC:dph] +synonym: "gamma-glutamyltranspeptidase complex" EXACT [GOC:dph] +synonym: "glutamine amidotransferase II complex" NARROW [PMID:22277648] +synonym: "glutathionase complex" EXACT [GOC:dph] +is_a: GO:1905368 ! peptidase complex +created_by: dph +creation_date: 2014-11-24T14:38:08Z + +[Term] +id: GO:0061673 +name: mitotic spindle astral microtubule +namespace: cellular_component +def: "Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GOC:dph] +is_a: GO:0000235 ! astral microtubule +intersection_of: GO:0000235 ! astral microtubule +intersection_of: part_of GO:0072686 ! mitotic spindle +relationship: part_of GO:0072686 ! mitotic spindle +created_by: dph +creation_date: 2014-12-08T18:27:20Z + +[Term] +id: GO:0061674 +name: gap filling involved in double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining." [GOC:dph] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: dph +creation_date: 2015-01-05T10:07:32Z + +[Term] +id: GO:0061675 +name: RBL family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose." [PMID:22312473] +synonym: "rhamnose-binding lectin family protein binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: dph +creation_date: 2015-01-10T18:22:42Z + +[Term] +id: GO:0061676 +name: importin-alpha family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the importin-alpha family." [PMID:15350979, PMID:17170104, PMID:23734157] +is_a: GO:0005515 ! protein binding +created_by: dph +creation_date: 2015-01-10T18:25:22Z + +[Term] +id: GO:0061677 +name: 2-dehydro-3-deoxy-D-gluconate aldolase activity +namespace: molecular_function +alt_id: GO:0043725 +def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde." [EC:4.1.2.51, GOC:dph, PMID:12824170, RHEA:35583] +synonym: "2-keto-3-deoxygluconate aldolase activity" EXACT [] +synonym: "KDG aldolase activity" EXACT [] +xref: EC:4.1.2.51 +xref: MetaCyc:4.1.2.51-RXN +xref: MetaCyc:DHDOGALDOL-RXN +xref: RHEA:35583 +is_a: GO:0016832 ! aldehyde-lyase activity +created_by: dph +creation_date: 2015-01-15T13:46:25Z + +[Term] +id: GO:0061678 +name: Entner-Doudoroff pathway +namespace: biological_process +def: "A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate." [GOC:dph, PMID:12921536] +xref: MetaCyc:Entner-Doudoroff-Pathways +is_a: GO:0044275 ! cellular carbohydrate catabolic process +created_by: dph +creation_date: 2015-01-16T15:28:25Z + +[Term] +id: GO:0061679 +name: Entner-Doudoroff pathway through gluconate +namespace: biological_process +def: "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate." [GOC:dph, PMID:12921536] +synonym: "gluconate pathway" RELATED [] +is_a: GO:0061678 ! Entner-Doudoroff pathway +relationship: has_part GO:0047929 ! gluconate dehydratase activity +relationship: has_part GO:0047935 ! glucose 1-dehydrogenase (NADP+) activity +created_by: dph +creation_date: 2015-01-16T15:41:22Z + +[Term] +id: GO:0061680 +name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde +namespace: biological_process +def: "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde." [GOC:dph, MetaCyc:ENTNER-DOUDOROFF-PWY-II, PMID:12921536] +xref: MetaCyc:ENTNER-DOUDOROFF-PWY-II +is_a: GO:0061679 ! Entner-Doudoroff pathway through gluconate +created_by: dph +creation_date: 2015-01-22T08:51:31Z + +[Term] +id: GO:0061681 +name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate +namespace: biological_process +def: "The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate." [GOC:dph, MetaCyc:ENTNER-DOUFDOROFF-PWY-III, PMID:12921536] +xref: MetaCyc:ENTNER-DOUDOROFF-PWY-III +is_a: GO:0061679 ! Entner-Doudoroff pathway through gluconate +relationship: has_part GO:0008673 ! 2-dehydro-3-deoxygluconokinase activity +created_by: dph +creation_date: 2015-01-22T08:55:22Z + +[Term] +id: GO:0061682 +name: seminal vesicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0061107 ! seminal vesicle development +created_by: dph +creation_date: 2015-03-04T13:33:49Z + +[Term] +id: GO:0061683 +name: branching involved in seminal vesicle morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376] +synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph] +synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph] +synonym: "seminal vesicle branching" EXACT [GOC:dph] +synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: GO:0061138 ! morphogenesis of a branching epithelium +intersection_of: part_of GO:0061682 ! seminal vesicle morphogenesis +relationship: part_of GO:0061108 ! seminal vesicle epithelium development +relationship: part_of GO:0061682 ! seminal vesicle morphogenesis +created_by: dph +creation_date: 2015-03-04T13:39:47Z + +[Term] +id: GO:0061684 +name: chaperone-mediated autophagy +namespace: biological_process +def: "The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded." [GOC:pad, GOC:PARL, PMID:22743996, PMID:23434281] +synonym: "CASA" BROAD [PMID:23434281] +synonym: "chaperone-assisted selective autophagy" EXACT [PMID:23434281] +synonym: "CMA" BROAD [PMID:22743996] +xref: Wikipedia:Chaperone-mediated_autophagy +is_a: GO:0006914 ! autophagy +is_a: GO:0030163 ! protein catabolic process +relationship: has_part GO:0005102 ! signaling receptor binding +relationship: has_part GO:0072321 ! chaperone-mediated protein transport +created_by: dph +creation_date: 2015-03-04T14:35:26Z + +[Term] +id: GO:0061685 +name: diphthine methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol." [GOC:dph, PMID:24739148, RHEA:42656] +xref: EC:3.1.1.97 +xref: RHEA:42656 +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: dph +creation_date: 2015-03-04T16:00:21Z + +[Term] +id: GO:0061686 +name: hercynylcysteine sulfoxide synthase +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine + O2 <=> hercynylcysteine sulfoxide + H2O." [GOC:dph, PMID:28577] +synonym: "hercynylcysteine S-oxide synthase" EXACT [GOC:dph] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +relationship: part_of GO:0052699 ! ergothioneine biosynthetic process +created_by: dph +creation_date: 2015-03-06T15:08:51Z + +[Term] +id: GO:0061687 +name: detoxification of inorganic compound +namespace: biological_process +def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] +is_a: GO:0098754 ! detoxification +created_by: dph +creation_date: 2015-03-09T09:16:23Z + +[Term] +id: GO:0061688 +name: glycolytic process via Entner-Doudoroff Pathway +namespace: biological_process +def: "A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes." [GOC:dph, PMID:9657988] +synonym: "gluconate pathway" RELATED [] +is_a: GO:0006096 ! glycolytic process +created_by: dph +creation_date: 2015-03-12T14:39:00Z + +[Term] +id: GO:0061689 +name: tricellular tight junction +namespace: cellular_component +def: "An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet." [GOC:dk, GOC:dph, PMID:22520461, PMID:25822906] +is_a: GO:0070160 ! tight junction +created_by: dph +creation_date: 2015-04-12T10:34:19Z + +[Term] +id: GO:0061690 +name: lipoamidase activity +namespace: molecular_function +def: "Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein." [GOC:dph, PMID:14086741] +synonym: "lipoyl-X-hydrolase" EXACT [PMID:14086741] +xref: MetaCyc:RXN-13031 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: dph +creation_date: 2015-05-05T10:06:49Z + +[Term] +id: GO:0061691 +name: detoxification of hydrogen peroxide +namespace: biological_process +def: "Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration." [GOC:dph] +is_a: GO:0042743 ! hydrogen peroxide metabolic process +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:0042542 ! response to hydrogen peroxide +created_by: dph +creation_date: 2015-05-05T12:42:18Z + +[Term] +id: GO:0061692 +name: cellular detoxification of hydrogen peroxide +namespace: biological_process +def: "Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration." [GOC:dph, GOC:vw] +is_a: GO:0061691 ! detoxification of hydrogen peroxide +is_a: GO:0098869 ! cellular oxidant detoxification +relationship: part_of GO:0070301 ! cellular response to hydrogen peroxide +created_by: dph +creation_date: 2015-05-05T12:46:20Z + +[Term] +id: GO:0061693 +name: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine." [EC:2.7.8.37, GOC:dph, PMID:22089136] +xref: EC:2.7.8.37 +xref: MetaCyc:RXN0-6732 +xref: RHEA:34679 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: dph +creation_date: 2015-05-06T10:04:04Z + +[Term] +id: GO:0061694 +name: alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex +namespace: cellular_component +def: "A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity." [GOC:dph, PMID:22089136] +comment: An example of this complex is PhnI (P16687) in Escherichia coli. +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: dph +creation_date: 2015-05-06T10:12:02Z + +[Term] +id: GO:0061695 +name: transferase complex, transferring phosphorus-containing groups +namespace: cellular_component +def: "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph] +is_a: GO:1990234 ! transferase complex +created_by: dph +creation_date: 2015-05-06T11:22:38Z + +[Term] +id: GO:0061696 +name: pituitary gonadotropin complex +namespace: cellular_component +def: "A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function." [GOC:dph, PMID:11420129] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005576 ! extracellular region +created_by: dph +creation_date: 2015-05-06T13:11:18Z + +[Term] +id: GO:0061697 +name: protein-glutaryllysine deglutarylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [GOC:dph, PMID:24703693] +comment: This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide. +xref: RHEA:47664 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +relationship: part_of GO:0061699 ! peptidyl-lysine deglutarylation +created_by: dph +creation_date: 2015-05-07T10:55:53Z + +[Term] +id: GO:0061698 +name: protein deglutarylation +namespace: biological_process +def: "The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein." [GOC:dph, PMID:24703693] +is_a: GO:0035601 ! protein deacylation +created_by: dph +creation_date: 2015-05-07T11:02:31Z + +[Term] +id: GO:0061699 +name: peptidyl-lysine deglutarylation +namespace: biological_process +def: "The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein." [GOC:dph, PMID:24703693] +is_a: GO:0061698 ! protein deglutarylation +created_by: dph +creation_date: 2015-05-07T11:04:42Z + +[Term] +id: GO:0061700 +name: GATOR2 complex +namespace: cellular_component +def: "A multiprotein subcomplex of GATOR that regulates mTOR signaling by interacting with the Rag GTPases. In humans this complex consists of Mios, WDR24, WDR59, Seh1L, Sec13." [GOC:rb, PMID:23723238] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0035859 ! Seh1-associated complex +created_by: dph +creation_date: 2015-05-07T11:13:27Z + +[Term] +id: GO:0061701 +name: bacterial outer membrane vesicle +namespace: cellular_component +def: "A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes." [GOC:dph, GOC:pr, PMID:20596524] +is_a: GO:1903561 ! extracellular vesicle +created_by: dph +creation_date: 2015-05-07T13:53:47Z + +[Term] +id: GO:0061702 +name: inflammasome complex +namespace: cellular_component +def: "A cytosolic protein complex that is capable of activating caspase-1." [GOC:dph, PMID:17599095] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: dph +creation_date: 2015-05-08T14:30:54Z + +[Term] +id: GO:0061703 +name: pyroptosome complex +namespace: cellular_component +def: "A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis." [GOC:dph, PMID:17599095] +synonym: "ASC pyroptosome" EXACT [PMID:17599095] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2015-05-08T14:43:37Z + +[Term] +id: GO:0061704 +name: glycolytic process from sucrose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules." [GOC:dph, GOC:glycolysis, PMID:15012287] +is_a: GO:0005987 ! sucrose catabolic process +is_a: GO:0006096 ! glycolytic process +created_by: dph +creation_date: 2015-06-11T13:26:28Z + +[Term] +id: GO:0061705 +name: sucrose catabolic process to fructose-6-phosphate through glucose and fructose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates." [GOC:dph, GOC:glycolysis, MetaCyc:PWY-621, PMID:15012287] +xref: MetaCyc:PWY-621 +is_a: GO:0005987 ! sucrose catabolic process +relationship: has_part GO:0004340 ! glucokinase activity +relationship: has_part GO:0008865 ! fructokinase activity +created_by: dph +creation_date: 2015-06-11T13:32:05Z + +[Term] +id: GO:0061706 +name: glycolytic process from sucrose through glucose and fructose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules." [GOC:dph, GOC:glycolysis, MetaCyc:PWY-1042, PMID:15012287] +xref: MetaCyc:PWY-1042 +is_a: GO:0061615 ! glycolytic process through fructose-6-phosphate +is_a: GO:0061704 ! glycolytic process from sucrose +created_by: dph +creation_date: 2015-06-11T13:40:32Z + +[Term] +id: GO:0061707 +name: extracellular exosome macropinocytosis +namespace: biological_process +def: "The single-organism macropinocytosis process that results in the uptake of an extracellular exosome." [GOC:dph, PMID:24951588] +is_a: GO:0044351 ! macropinocytosis +is_a: GO:0051650 ! establishment of vesicle localization +created_by: dph +creation_date: 2015-06-15T16:02:38Z + +[Term] +id: GO:0061708 +name: tRNA-5-taurinomethyluridine 2-sulfurtransferase +namespace: molecular_function +def: "Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+." [GOC:dph, PMID:15509579] +xref: MetaCyc:RXN-16821 +xref: Reactome:R-HSA-6787447 "TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA" +is_a: GO:0016783 ! sulfurtransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +created_by: dph +creation_date: 2015-06-16T09:02:23Z + +[Term] +id: GO:0061709 +name: reticulophagy +namespace: biological_process +alt_id: GO:1990766 +def: "The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions." [GOC:autophagy, GOC:dph, PMID:22481944, PMID:24060720, PMID:26040717] +synonym: "autophagy of the endoplasmic reticulum" EXACT [] +synonym: "autophagy of the ER" EXACT [] +synonym: "endoplasmic reticulum degradation" RELATED [] +synonym: "ER degradation" RELATED [] +synonym: "ER-phagy" EXACT [] +is_a: GO:0061912 ! selective autophagy +is_a: GO:1903008 ! organelle disassembly +relationship: has_part GO:1905692 ! endoplasmic reticulum disassembly +created_by: dph +creation_date: 2015-06-18T15:15:48Z + +[Term] +id: GO:0061710 +name: L-threonylcarbamoyladenylate synthase +namespace: molecular_function +def: "Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O." [EC:2.7.7.87] +xref: EC:2.7.7.87 +xref: MetaCyc:RXN-14569 +xref: RHEA:36407 +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: dph +creation_date: 2015-06-23T08:25:14Z + +[Term] +id: GO:0061711 +name: N(6)-L-threonylcarbamoyladenine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA." [EC:2.3.1.234] +xref: EC:2.3.1.234 +xref: MetaCyc:RXN-14570 +xref: Reactome:R-HSA-6784494 "EKC complex threonylcarbamoylates A37 of tRNAs" +xref: RHEA:37059 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: dph +creation_date: 2015-06-23T08:34:44Z + +[Term] +id: GO:0061712 +name: tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase +namespace: molecular_function +def: "Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine." [EC:2.8.4.5] +xref: EC:2.8.4.5 +xref: MetaCyc:RXN-14531 +xref: RHEA:37075 +is_a: GO:0035596 ! methylthiotransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +created_by: dph +creation_date: 2015-06-23T08:47:10Z + +[Term] +id: GO:0061713 +name: anterior neural tube closure +namespace: biological_process +def: "The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline." [GOC:BHF, GOC:dph, GOC:hal, PMID:17286298] +is_a: GO:0060606 ! tube closure +relationship: part_of GO:0001843 ! neural tube closure +created_by: dph +creation_date: 2015-06-23T10:13:41Z + +[Term] +id: GO:0061714 +name: folic acid receptor activity +namespace: molecular_function +def: "Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis." [GOC:BHF, GOC:hal] +synonym: "folate receptor activity" EXACT [] +is_a: GO:0038024 ! cargo receptor activity +relationship: has_part GO:0005542 ! folic acid binding +relationship: part_of GO:0015884 ! folic acid transport +relationship: part_of GO:0071231 ! cellular response to folic acid +created_by: dph +creation_date: 2015-06-23T13:36:07Z + +[Term] +id: GO:0061715 +name: miRNA 2'-O-methylation +namespace: biological_process +def: "The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:20705645] +is_a: GO:0001510 ! RNA methylation +is_a: GO:0010586 ! miRNA metabolic process +created_by: dph +creation_date: 2015-06-29T08:41:03Z + +[Term] +id: GO:0061716 +name: miRNA export from nucleus +namespace: biological_process +def: "The directed movement of a processed miRNA from the nucleus to the cytoplasm." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756] +is_a: GO:0097064 ! ncRNA export from nucleus +is_a: GO:1990428 ! miRNA transport +created_by: dph +creation_date: 2015-06-29T08:54:41Z + +[Term] +id: GO:0061718 +name: glucose catabolic process to pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate." [GOC:dph] +synonym: "glucose catabolism to pyruvate" EXACT [GOC:dph] +is_a: GO:0006007 ! glucose catabolic process +is_a: GO:0006090 ! pyruvate metabolic process +created_by: dph +creation_date: 2015-06-30T13:17:26Z + +[Term] +id: GO:0061719 +name: glucose catabolic process to pyruvate utilizing ADP +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions." [GOC:dph, MetaCyc:P341-PWY] +xref: MetaCyc:P341-PWY +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0061718 ! glucose catabolic process to pyruvate +relationship: has_part GO:0004332 ! fructose-bisphosphate aldolase activity +relationship: has_part GO:0004347 ! glucose-6-phosphate isomerase activity +relationship: has_part GO:0004618 ! phosphoglycerate kinase activity +relationship: has_part GO:0004619 ! phosphoglycerate mutase activity +relationship: has_part GO:0004807 ! triose-phosphate isomerase activity +relationship: has_part GO:0043797 ! glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity +relationship: has_part GO:0043844 ! ADP-specific phosphofructokinase activity +created_by: dph +creation_date: 2015-06-30T13:23:42Z + +[Term] +id: GO:0061720 +name: 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)." [GOC:dph, PMID:24463506] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0019694 ! alkanesulfonate metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +is_a: GO:1902777 ! 6-sulfoquinovose(1-) catabolic process +relationship: has_part GO:0061594 ! 6-deoxy-6-sulfofructose kinase activity +created_by: dph +creation_date: 2015-07-01T08:47:30Z + +[Term] +id: GO:0061721 +name: 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-) +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-)." [GOC:dph, PMID:14602517, PMID:24463506] +xref: MetaCyc:PWY-7446 +is_a: GO:0019694 ! alkanesulfonate metabolic process +is_a: GO:0051143 ! propanediol metabolic process +is_a: GO:1902777 ! 6-sulfoquinovose(1-) catabolic process +created_by: dph +creation_date: 2015-07-01T09:20:08Z + +[Term] +id: GO:0061722 +name: sulphoglycolysis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate." [GOC:dph, PMID:24463506] +synonym: "sulfoglycolysis" EXACT [PMID:14602597] +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0006734 ! NADH metabolic process +is_a: GO:0019674 ! NAD metabolic process +is_a: GO:0046034 ! ATP metabolic process +is_a: GO:1902777 ! 6-sulfoquinovose(1-) catabolic process +relationship: has_part GO:0004365 ! glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity +relationship: has_part GO:0004618 ! phosphoglycerate kinase activity +relationship: has_part GO:0004619 ! phosphoglycerate mutase activity +relationship: has_part GO:0004634 ! phosphopyruvate hydratase activity +relationship: has_part GO:0004807 ! triose-phosphate isomerase activity +created_by: dph +creation_date: 2015-07-01T09:44:30Z + +[Term] +id: GO:0061723 +name: glycophagy +namespace: biological_process +def: "The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions." [GOC:autophagy, PMID:21893048] +is_a: GO:0005980 ! glycogen catabolic process +is_a: GO:0061912 ! selective autophagy +created_by: dph +creation_date: 2015-07-08T13:36:51Z + +[Term] +id: GO:0061724 +name: lipophagy +namespace: biological_process +def: "The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions." [GOC:autophagy, PMID:23708524, PMID:26076903] +is_a: GO:0061912 ! selective autophagy +relationship: has_part GO:1905691 ! lipid droplet disassembly +created_by: dph +creation_date: 2015-07-08T13:38:19Z + +[Term] +id: GO:0061725 +name: cytosolic lipolysis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases." [GOC:autophagy] +is_a: GO:0044242 ! cellular lipid catabolic process +relationship: occurs_in GO:0005829 ! cytosol +created_by: dph +creation_date: 2015-07-08T13:42:15Z + +[Term] +id: GO:0061726 +name: mitochondrion disassembly +namespace: biological_process +def: "The disaggregation of a mitochondrion into its constituent components." [GOC:autophagy, PMID:25009776] +synonym: "mitochondrion degradation" EXACT [GOC:autophagy] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:1903008 ! organelle disassembly +created_by: dph +creation_date: 2015-07-08T13:59:16Z + +[Term] +id: GO:0061727 +name: methylglyoxal catabolic process to lactate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate." [GOC:dph, PMID:2198020] +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0051596 ! methylglyoxal catabolic process +created_by: dph +creation_date: 2015-07-21T17:25:57Z + +[Term] +id: GO:0061728 +name: GDP-mannose biosynthetic process from mannose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose." [GOC:dph, PMID:16339137, PMID:24218558] +is_a: GO:0006013 ! mannose metabolic process +is_a: GO:0009298 ! GDP-mannose biosynthetic process +created_by: dph +creation_date: 2015-07-24T14:44:04Z + +[Term] +id: GO:0061729 +name: GDP-mannose biosynthetic process from fructose-6-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate." [GOC:dph, PMID:16339137] +xref: Reactome:R-HSA-446205 "Synthesis of GDP-mannose, Homo sapiens" +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0009298 ! GDP-mannose biosynthetic process +is_a: GO:0019637 ! organophosphate metabolic process +created_by: dph +creation_date: 2015-07-24T14:50:44Z + +[Term] +id: GO:0061730 +name: C-rich strand telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with C-rich, single-stranded, telomere-associated DNA." [GOC:dph, GOC:kmv, PMID:18329362] +is_a: GO:0043047 ! single-stranded telomeric DNA binding +created_by: dph +creation_date: 2015-08-20T09:08:27Z + +[Term] +id: GO:0061731 +name: ribonucleoside-diphosphate reductase activity +namespace: molecular_function +def: "Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor." [GOC:dph, GOC:vw, PMID:16756507] +synonym: "adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [] +synonym: "aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [] +synonym: "anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [] +synonym: "class I ribonucleotide reductase activity" RELATED [] +synonym: "class II ribonucleoside-diphosphate reductase activity" RELATED [] +synonym: "class II ribonucleotide reductase activity" RELATED [] +synonym: "class III ribonucleotide reductase activity" RELATED [] +synonym: "nucleoside diphosphate reductase activity" RELATED [] +synonym: "purine/pyrimidine nucleoside diphosphate reduction" RELATED [] +synonym: "ribonucleoside 5'-diphosphate reductase activity" EXACT [] +synonym: "ribonucleotide diphosphate reductase activity" EXACT [] +synonym: "ribonucleotide reductase activity" BROAD [] +synonym: "RNR" RELATED [] +is_a: GO:0016728 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor +created_by: dph +creation_date: 2015-08-24T07:25:59Z + +[Term] +id: GO:0061732 +name: mitochondrial acetyl-CoA biosynthetic process from pyruvate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA." [GOC:dph, ISBN:0201090910] +xref: Reactome:R-HSA-372342.1 +xref: Reactome:R-HSA-71397.1 +is_a: GO:0006086 ! acetyl-CoA biosynthetic process from pyruvate +created_by: dph +creation_date: 2015-08-24T13:44:02Z + +[Term] +id: GO:0061733 +name: peptide-lysine-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide." [GOC:dph] +xref: Reactome:R-HSA-6811508 "ING2-bound EP300 acetylates TP53" +xref: Reactome:R-HSA-8951966 "EP300 acetylates RUNX3" +xref: Reactome:R-HSA-9617758 "EP300,CREBBP acetylate FOXO4" +xref: Reactome:R-HSA-9620515 "KAT2B,EP300 acetylate FOXO3 under oxidative stress" +xref: Reactome:R-HSA-9626945 "CREBBP acetylates FOXO1" +is_a: GO:0034212 ! peptide N-acetyltransferase activity +created_by: dph +creation_date: 2015-09-10T10:22:19Z + +[Term] +id: GO:0061734 +name: parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190] +synonym: "Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +synonym: "PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +is_a: GO:0098779 ! positive regulation of mitophagy in response to mitochondrial depolarization +created_by: dph +creation_date: 2015-09-14T13:48:57Z + +[Term] +id: GO:0061735 +name: DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190] +synonym: "dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +is_a: GO:0098779 ! positive regulation of mitophagy in response to mitochondrial depolarization +created_by: dph +creation_date: 2015-09-14T14:00:43Z + +[Term] +id: GO:0061736 +name: engulfment of target by autophagosome +namespace: biological_process +def: "The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL] +is_a: GO:0010324 ! membrane invagination +intersection_of: GO:0010324 ! membrane invagination +intersection_of: part_of GO:0000045 ! autophagosome assembly +relationship: part_of GO:0000045 ! autophagosome assembly +created_by: dph +creation_date: 2015-09-14T14:10:24Z + +[Term] +id: GO:0061737 +name: leukotriene signaling pathway +namespace: biological_process +def: "A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription." [GOC:dph, PMID:21771892] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +property_value: RO:0002161 NCBITaxon:4751 +created_by: dph +creation_date: 2015-09-15T12:58:21Z + +[Term] +id: GO:0061738 +name: late endosomal microautophagy +namespace: biological_process +def: "The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:21238931] +is_a: GO:0006914 ! autophagy +created_by: dph +creation_date: 2015-09-24T14:40:02Z + +[Term] +id: GO:0061739 +name: protein lipidation involved in autophagosome assembly +namespace: biological_process +def: "The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly." [GOC:autophagy, GOC:dph, PMID:11096062, PMID:11100732, PMID:15277523] +is_a: GO:0006501 ! C-terminal protein lipidation +intersection_of: GO:0006501 ! C-terminal protein lipidation +intersection_of: part_of GO:0000045 ! autophagosome assembly +relationship: has_part GO:0019779 ! Atg8 activating enzyme activity +relationship: part_of GO:0000045 ! autophagosome assembly +created_by: dph +creation_date: 2015-10-14T12:02:01Z + +[Term] +id: GO:0061740 +name: protein targeting to lysosome involved in chaperone-mediated autophagy +namespace: biological_process +def: "The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor." [GOC:dph, GOC:pad, GOC:PARL, PMID:22748206] +is_a: GO:0006622 ! protein targeting to lysosome +is_a: GO:0071211 ! protein targeting to vacuole involved in autophagy +intersection_of: GO:0006622 ! protein targeting to lysosome +intersection_of: part_of GO:0061684 ! chaperone-mediated autophagy +relationship: has_part GO:0005102 ! signaling receptor binding +relationship: has_part GO:0051087 ! chaperone binding +relationship: part_of GO:0061684 ! chaperone-mediated autophagy +created_by: dph +creation_date: 2015-10-21T08:41:29Z + +[Term] +id: GO:0061741 +name: chaperone-mediated protein transport involved in chaperone-mediated autophagy +namespace: biological_process +def: "The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy." [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:22748206] +is_a: GO:0071806 ! protein transmembrane transport +is_a: GO:0072321 ! chaperone-mediated protein transport +intersection_of: GO:0072321 ! chaperone-mediated protein transport +intersection_of: part_of GO:0061684 ! chaperone-mediated autophagy +relationship: has_part GO:0043335 ! protein unfolding +relationship: part_of GO:0061684 ! chaperone-mediated autophagy +created_by: dph +creation_date: 2015-10-21T08:56:33Z + +[Term] +id: GO:0061742 +name: chaperone-mediated autophagy translocation complex +namespace: cellular_component +def: "A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy." [GOC:dph, GOC:pad, GOC:PARL, PMID:20797626] +synonym: "chaperone-mediated autophagy receptor complex" RELATED [GOC:dph, GOC:pad, GOC:PARL] +synonym: "CMA receptor complex" RELATED [GOC:dph, GOC:pad, GOC:PARL] +synonym: "CMA translocation complex" EXACT [GOC:dph, GOC:pad, GOC:PARL, PMID:20797626] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005765 ! lysosomal membrane +created_by: dph +creation_date: 2015-10-23T07:39:04Z + +[Term] +id: GO:0061743 +name: motor learning +namespace: biological_process +def: "Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience." [GOC:bf, GOC:PARL, Wikipedia:Motor_learning] +is_a: GO:0007612 ! learning +created_by: dph +creation_date: 2015-11-09T12:40:29Z + +[Term] +id: GO:0061744 +name: motor behavior +namespace: biological_process +def: "The specific neuromuscular movement of a single organism in response to external or internal stimuli." [GOC:bf, GOC:PARL, PMID:25318560] +is_a: GO:0007610 ! behavior +created_by: dph +creation_date: 2015-11-09T12:43:11Z + +[Term] +id: GO:0061746 +name: obsolete single-stranded DNA-dependent GTPase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction." [GOC:dph, PMID:26277776] +comment: This term was obsoleted because there is no evidence that this reaction occurs under physiological conditions. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19078 xsd:anyURI +is_obsolete: true +created_by: dph +creation_date: 2015-11-11T12:50:19Z + +[Term] +id: GO:0061749 +name: forked DNA-dependent helicase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA." [GOC:dph, PMID:26277776] +is_a: GO:0003678 ! DNA helicase activity +created_by: dph +creation_date: 2015-11-11T13:10:51Z + +[Term] +id: GO:0061750 +name: acid sphingomyelin phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment." [GOC:dph, PMID:26493087] +synonym: "acid SMase" RELATED [PMID:26493087] +synonym: "acid sphingomyelinase" EXACT [PMID:26493087] +is_a: GO:0004767 ! sphingomyelin phosphodiesterase activity +created_by: dph +creation_date: 2015-11-11T14:47:45Z + +[Term] +id: GO:0061751 +name: neutral sphingomyelin phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment." [GOC:dph, PMID:26493087] +synonym: "neutral SMase" EXACT [PMID:26493087] +synonym: "neutral sphingomyelinase" EXACT [GOC:26493087] +is_a: GO:0004767 ! sphingomyelin phosphodiesterase activity +created_by: dph +creation_date: 2015-11-11T14:48:08Z + +[Term] +id: GO:0061752 +name: telomeric repeat-containing RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats." [GOC:BHF, GOC:BHF_telomere, GOC:dph, GOC:jbu, PMID:20655916] +synonym: "TERRA binding" EXACT [PMID:20655916] +is_a: GO:0003723 ! RNA binding +created_by: dph +creation_date: 2015-11-13T07:55:06Z + +[Term] +id: GO:0061753 +name: substrate localization to autophagosome +namespace: biological_process +def: "The localization process by which an autophagic substrate is delivered to a forming autophagosome." [GOC:dph, GOC:pad, GOC:PARL, PMID:23545414] +synonym: "substrate sequestration to autophagosome" EXACT [] +synonym: "substrate sequestration to phagophore" EXACT [] +is_a: GO:0051649 ! establishment of localization in cell +relationship: part_of GO:0000045 ! autophagosome assembly +created_by: dph +creation_date: 2015-11-20T11:14:22Z + +[Term] +id: GO:0061754 +name: negative regulation of circulating fibrinogen levels +namespace: biological_process +def: "Any process that reduces the quantity of fibrinogen circulating in the bloodstream." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:20570858] +is_a: GO:0044537 ! regulation of circulating fibrinogen levels +created_by: dph +creation_date: 2016-02-29T16:19:09Z + +[Term] +id: GO:0061755 +name: positive regulation of circulating fibrinogen levels +namespace: biological_process +def: "Any process that increases the quantity of fibrinogen circulating in the bloodstream." [GOC:bf, GOC:BHF, GOC:BHF_miRNA, PMID:20570858] +is_a: GO:0044537 ! regulation of circulating fibrinogen levels +created_by: dph +creation_date: 2016-02-29T16:26:49Z + +[Term] +id: GO:0061756 +name: leukocyte adhesion to vascular endothelial cell +namespace: biological_process +def: "The attachment of a leukocyte to vascular endothelial cell via adhesion molecules." [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:23897866] +is_a: GO:0007159 ! leukocyte cell-cell adhesion +created_by: dph +creation_date: 2016-02-29T16:42:11Z + +[Term] +id: GO:0061757 +name: leukocyte adhesion to arterial endothelial cell +namespace: biological_process +def: "The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules." [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:22267480] +is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell +created_by: dph +creation_date: 2016-02-29T16:49:38Z + +[Term] +id: GO:0061758 +name: 2-hydroxyglutarate dehydrogenase activity, forward reaction +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor." [EC:1.1.99.2, GOC:dph, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN] +synonym: "alpha-ketoglutarate reductase activity, reverse reaction" EXACT [GOC:dph] +xref: RHEA:21253 +is_a: GO:0047545 ! 2-hydroxyglutarate dehydrogenase activity +created_by: dph +creation_date: 2016-03-07T08:28:58Z + +[Term] +id: GO:0061759 +name: alpha-ketoglutarate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + reduced acceptor -> (S)-2-hydroxyglutarate + acceptor." [EC:1.1.99.2, GOC:dph, PMID:26774271] +synonym: "2-hydroxyglutarate dehydrogenase activity, reverse reaction" EXACT [GOC:dph] +synonym: "2-ketoglutarate reductase activity" RELATED [GOC:dph] +synonym: "2-oxoglutarate reductase activity" RELATED [GOC:dph] +synonym: "D-2HG reductase activity" RELATED [GOC:dph] +xref: RHEA:21254 +is_a: GO:0047545 ! 2-hydroxyglutarate dehydrogenase activity +created_by: dph +creation_date: 2016-03-07T08:38:57Z + +[Term] +id: GO:0061760 +name: antifungal innate immune response +namespace: biological_process +def: "An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens." [GOC:dph, PMID:22470487] +is_a: GO:0045087 ! innate immune response +is_a: GO:0050832 ! defense response to fungus +created_by: dph +creation_date: 2016-03-07T08:53:08Z + +[Term] +id: GO:0061761 +name: alpha-latrotoxin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alpha-latrotoxin receptor." [GOC:dph, PMID:21724987] +synonym: "lasso receptor binding" EXACT [GOC:dph, PMID:21724987] +synonym: "latrophilin binding" EXACT [GOC:dph, PMID:21724987] +is_a: GO:0001664 ! G protein-coupled receptor binding +created_by: dph +creation_date: 2016-04-13T10:46:42Z + +[Term] +id: GO:0061762 +name: CAMKK-AMPK signaling cascade +namespace: biological_process +def: "A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity." [GOC:dph, GOC:pad, GOC:PARL, PMID:23010169, PMID:24709372] +synonym: "stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:dph] +is_a: GO:0019722 ! calcium-mediated signaling +is_a: GO:0099004 ! calmodulin dependent kinase signaling pathway +relationship: has_part GO:0005516 ! calmodulin binding +created_by: dph +creation_date: 2016-04-14T12:59:31Z + +[Term] +id: GO:0061763 +name: multivesicular body-lysosome fusion +namespace: biological_process +def: "The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle." [GOC:dph, GOC:pad, GOC:PARL, PMID:21118109] +synonym: "fusion of multivesicular body to lysosome" EXACT [GOC:dph] +synonym: "fusion of MVB to lysosome" EXACT [GOC:dph] +synonym: "MVB-lysosome fusion" EXACT [GOC:dph] +is_a: GO:0090174 ! organelle membrane fusion +relationship: part_of GO:0032510 ! endosome to lysosome transport via multivesicular body sorting pathway +created_by: dph +creation_date: 2016-04-15T07:12:40Z + +[Term] +id: GO:0061764 +name: late endosome to lysosome transport via multivesicular body sorting pathway +namespace: biological_process +def: "The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome." [GOC:dph] +is_a: GO:0032510 ! endosome to lysosome transport via multivesicular body sorting pathway +is_a: GO:0045324 ! late endosome to vacuole transport +is_a: GO:1902774 ! late endosome to lysosome transport +created_by: dph +creation_date: 2016-04-19T09:29:57Z + +[Term] +id: GO:0061765 +name: modulation by virus of host NIK/NF-kappaB signaling +namespace: biological_process +def: "Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:26764146] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:1901222 ! regulation of NIK/NF-kappaB signaling +created_by: dph +creation_date: 2016-04-19T10:41:22Z + +[Term] +id: GO:0061766 +name: positive regulation of lung blood pressure +namespace: biological_process +def: "The process that increases the force with which blood travels through the lungs." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:22161164] +synonym: "positive regulation of pulmonary blood pressure" EXACT [GOC:dph] +is_a: GO:0014916 ! regulation of lung blood pressure +created_by: dph +creation_date: 2016-04-27T11:54:34Z + +[Term] +id: GO:0061767 +name: negative regulation of lung blood pressure +namespace: biological_process +def: "The process that decreases the force with which blood travels through the lungs." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:dph, PMID:22161164] +synonym: "negative regulation of pulmonary blood pressure" EXACT [GOC:dph] +is_a: GO:0014916 ! regulation of lung blood pressure +created_by: dph +creation_date: 2016-04-27T11:58:55Z + +[Term] +id: GO:0061768 +name: magnesium:sodium antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in)." [GOC:pad, GOC:PARL, PMID:22031603] +is_a: GO:0015081 ! sodium ion transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +created_by: dph +creation_date: 2016-05-04T14:45:45Z + +[Term] +id: GO:0061769 +name: ribosylnicotinate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide." [GOC:dph, PMID:17914902] +xref: Reactome:R-HSA-8869606 "NMRK1 phosphorylates NAR to yield NAMN" +xref: Reactome:R-HSA-8869607 "NMRK2 phosphorylates NAR to yield NAMN" +is_a: GO:0016301 ! kinase activity +created_by: dph +creation_date: 2016-05-05T14:41:44Z + +[Term] +id: GO:0061770 +name: translation elongation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation." [GOC:dph] +is_a: GO:0005515 ! protein binding +created_by: dph +creation_date: 2016-07-09T09:31:11Z + +[Term] +id: GO:0061771 +name: response to caloric restriction +namespace: biological_process +def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake." [GOC:dph, PMID:15520862] +is_a: GO:0006950 ! response to stress +is_a: GO:0031667 ! response to nutrient levels +created_by: dph +creation_date: 2016-07-09T09:40:32Z + +[Term] +id: GO:0061772 +name: xenobiotic transport across blood-nerve barrier +namespace: biological_process +def: "The directed movement of a xenobiotic through the blood-nerve barrier." [GOC:dph, PMID:22733753] +synonym: "drug transport across blood-nerve barrier" RELATED [] +synonym: "drug transport across perineurial barrier" EXACT [PMID:22733753] +is_a: GO:0042908 ! xenobiotic transport +created_by: dph +creation_date: 2016-07-09T09:59:59Z + +[Term] +id: GO:0061773 +name: eNoSc complex +namespace: cellular_component +def: "A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation." [GOC:BHM, Intact:EBI-11789632, Intact:EBI-11790279, PMID:18485871] +synonym: "energy dependent nucleolar silencing complex" EXACT [] +is_a: GO:0005677 ! chromatin silencing complex +relationship: part_of GO:0005730 ! nucleolus +created_by: dph +creation_date: 2016-07-09T10:12:30Z + +[Term] +id: GO:0061774 +name: cohesin unloading +namespace: biological_process +def: "Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA." [GOC:dph, GOC:vw, PMID:26687354] +synonym: "DNA exit from the cohesin ring" EXACT [GOC:dph, GOC:vw] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:0045875 ! negative regulation of sister chromatid cohesion +created_by: dph +creation_date: 2016-07-13T12:40:25Z + +[Term] +id: GO:0061775 +name: cohesin ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, coupled to the topological linking or unlinking of a cohesin ring complex around homologous chromosomes." [GOC:dph, GOC:vw, PMID:26687354] +is_a: GO:0008094 ! DNA-dependent ATPase activity +created_by: dph +creation_date: 2016-07-13T12:54:43Z + +[Term] +id: GO:0061776 +name: topological DNA entrapment activity +namespace: molecular_function +def: "The DNA binding activity by which a protein complex interacts selectively and non-covalently with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring." [GOC:dph, GOC:vw, PMID:16179255, PMID:26687354, PMID:27797071] +is_a: GO:0003690 ! double-stranded DNA binding +created_by: dph +creation_date: 2016-07-13T13:10:15Z + +[Term] +id: GO:0061777 +name: obsolete DNA clamp activity +namespace: molecular_function +def: "OBSOLETE. A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA." [GOC:dph, GOC:vw, PMID:1349852] +comment: The reason for obsoletion is that the term captures the structure of a complex, not a specific function. +is_obsolete: true +created_by: dph +creation_date: 2016-07-13T13:15:24Z + +[Term] +id: GO:0061778 +name: intracellular chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:dph, PMID:23092411] +is_a: GO:0005254 ! chloride channel activity +created_by: dph +creation_date: 2016-08-02T09:37:15Z + +[Term] +id: GO:0061779 +name: Tapasin-ERp57 complex +namespace: cellular_component +def: "Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role." [GOC:bhm, GOC:dph, Intact:EBI-11896237, Intact:EBI-9013963, PMID:17603487] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0042824 ! MHC class I peptide loading complex +created_by: dph +creation_date: 2016-08-05T12:12:08Z + +[Term] +id: GO:0061780 +name: mitotic cohesin loading +namespace: biological_process +def: "The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle." [GOC:dph, GOC:vw] +is_a: GO:0071921 ! cohesin loading +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0071921 ! cohesin loading +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0034087 ! establishment of mitotic sister chromatid cohesion +created_by: dph +creation_date: 2016-08-23T13:00:34Z + +[Term] +id: GO:0061781 +name: mitotic cohesin unloading +namespace: biological_process +def: "Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle." [GOC:dph, GOC:mah, GOC:vw] +is_a: GO:0061774 ! cohesin unloading +intersection_of: GO:0061774 ! cohesin unloading +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000278 ! mitotic cell cycle +created_by: dph +creation_date: 2016-08-24T09:43:07Z + +[Term] +id: GO:0061782 +name: vesicle fusion with vesicle +namespace: biological_process +def: "Fusion of the membrane of a transport vesicle with a target membrane on another vesicle." [GOC:bf, GOC:PARL, PMID:16618809] +synonym: "vesicle to vesicle fusion" EXACT [GOC:dph] +synonym: "vesicle-vesicle fusion" EXACT [GOC:dph] +is_a: GO:0006906 ! vesicle fusion +created_by: dph +creation_date: 2016-09-06T13:29:49Z + +[Term] +id: GO:0061783 +name: peptidoglycan muralytic activity +namespace: molecular_function +def: "A catalytic activity that contributes to the degradation of peptidoglycan." [GOC:dph, GOC:jh, PMID:22748813] +is_a: GO:0003824 ! catalytic activity +created_by: dph +creation_date: 2016-09-07T15:47:49Z + +[Term] +id: GO:0061784 +name: peptidoglycan N-acetylglucosaminidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan." [GOC:dph, GOC:jh, PMID:22748813] +is_a: GO:0015929 ! hexosaminidase activity +is_a: GO:0061783 ! peptidoglycan muralytic activity +created_by: dph +creation_date: 2016-09-07T16:17:03Z + +[Term] +id: GO:0061785 +name: peptidoglycan endopeptidase activity +namespace: molecular_function +def: "An endopeptidase activity that uses peptidoglycan as a substrate." [GOC:dph, GOC:jh, PMID:22748813] +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0061783 ! peptidoglycan muralytic activity +created_by: dph +creation_date: 2016-09-07T16:30:48Z + +[Term] +id: GO:0061786 +name: peptidoglycan stem peptide endopeptidase activity +namespace: molecular_function +def: "A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan." [GOC:dph, GOC:jh, PMID:22748813] +is_a: GO:0061785 ! peptidoglycan endopeptidase activity +created_by: dph +creation_date: 2016-09-07T16:47:04Z + +[Term] +id: GO:0061787 +name: peptidoglycan cross-bridge peptide endopeptidase activity +namespace: molecular_function +def: "A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge." [GOC:dph, GOC:jh, PMID:22748813] +synonym: "lysostaphin activity" NARROW [GOC:dph, GOC:jh, PMID:22748813] +is_a: GO:0061785 ! peptidoglycan endopeptidase activity +created_by: dph +creation_date: 2016-09-07T16:54:02Z + +[Term] +id: GO:0061788 +name: EGF repeat binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Epidermal Growth Factor (EGF) repeats." [GOC:25700513, GOC:dph, PMID:25155514] +synonym: "Epidermal growth factor domain binding" BROAD [GOC:dph] +synonym: "Epidermal Growth Factor repeat binding" RELATED [GOC:dph] +is_a: GO:0019904 ! protein domain specific binding +created_by: dph +creation_date: 2016-09-08T15:22:28Z + +[Term] +id: GO:0061789 +name: dense core granule priming +namespace: biological_process +def: "A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking." [GOC:bf, GOC:PARL, PMID:10899113, PMID:26575293] +synonym: "dense core vesicle priming" EXACT [PMID:26575293] +synonym: "large dense-core vesicle priming" EXACT [PMID:10899113] +synonym: "LDCV priming" EXACT [PMID:26575293] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:1990504 ! dense core granule exocytosis +created_by: dph +creation_date: 2016-09-08T15:41:30Z + +[Term] +id: GO:0061790 +name: dense core granule docking +namespace: biological_process +def: "The initial attachment of a dense core granule membrane to the plasma membrane." [GOC:bf, GOC:PARL, PMID:26575293] +is_a: GO:0006904 ! vesicle docking involved in exocytosis +intersection_of: GO:0048278 ! vesicle docking +intersection_of: part_of GO:1990504 ! dense core granule exocytosis +relationship: part_of GO:1990504 ! dense core granule exocytosis +created_by: dph +creation_date: 2016-09-08T15:51:49Z + +[Term] +id: GO:0061791 +name: GTPase motor activity +namespace: molecular_function +def: "Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of GTP." [GOC:dph, GOC:vw] +is_a: GO:0003774 ! motor activity +is_a: GO:0003924 ! GTPase activity +created_by: dph +creation_date: 2016-09-09T13:17:29Z + +[Term] +id: GO:0061792 +name: secretory granule maturation +namespace: biological_process +def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809] +is_a: GO:0021700 ! developmental maturation +is_a: GO:0033363 ! secretory granule organization +created_by: dph +creation_date: 2016-09-09T13:24:34Z + +[Term] +id: GO:0061793 +name: chromatin lock complex +namespace: cellular_component +def: "A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping." [GOC:bhm, GOC:dph, PMID:17540172] +synonym: "nucleosome bridging complex" RELATED [GOC:dph] +xref: IntAct:EBI-11790939 +xref: IntAct:EBI-11792170 +is_a: GO:0005677 ! chromatin silencing complex +created_by: dph +creation_date: 2016-09-09T13:47:27Z + +[Term] +id: GO:0061794 +name: conidium development +namespace: biological_process +def: "The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus." [GOC:di, GOC:dph] +is_a: GO:0048468 ! cell development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: dph +creation_date: 2016-09-17T09:53:51Z + +[Term] +id: GO:0061795 +name: Golgi lumen acidification +namespace: biological_process +def: "Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion." [GOC:dph, PMID:23447592] +is_a: GO:0051452 ! intracellular pH reduction +created_by: dph +creation_date: 2016-10-05T08:42:40Z + +[Term] +id: GO:0061796 +name: membrane addition at site of mitotic cytokinesis +namespace: biological_process +def: "A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion." [GOC:dph, GOC:vw] +is_a: GO:0007107 ! membrane addition at site of cytokinesis +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0007107 ! membrane addition at site of cytokinesis +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: dph +creation_date: 2016-10-05T12:06:11Z + +[Term] +id: GO:0061797 +name: pH-gated chloride channel activity +namespace: molecular_function +def: "A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH." [GOC:dph, PMID:27358471] +is_a: GO:0005254 ! chloride channel activity +is_a: GO:0022836 ! gated channel activity +created_by: dph +creation_date: 2016-10-06T07:11:14Z + +[Term] +id: GO:0061798 +name: GTP 3',8'-cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate." [GOC:dph, GOC:ik, PMID:25896388] +xref: EC:4.1.99.22 +xref: MetaCyc:RXN-8340 +is_a: GO:0016830 ! carbon-carbon lyase activity +created_by: dph +creation_date: 2016-10-06T14:26:11Z + +[Term] +id: GO:0061799 +name: cyclic pyranopterin monophosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate." [GOC:dph, GOC:ik, PMID:25896388] +xref: EC:4.6.1.17 +xref: MetaCyc:RXN-17809 +is_a: GO:0016849 ! phosphorus-oxygen lyase activity +created_by: dph +creation_date: 2016-10-06T14:36:56Z + +[Term] +id: GO:0061800 +name: fibronectin fibril +namespace: cellular_component +def: "A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks." [GOC:dph, PMID:20690820] +is_a: GO:0099512 ! supramolecular fiber +relationship: part_of GO:0031012 ! extracellular matrix +created_by: dph +creation_date: 2016-10-24T14:04:21Z + +[Term] +id: GO:0061801 +name: laminin-5B complex +namespace: cellular_component +def: "A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains." [GOC:dph, PMID:15979864] +synonym: "laminin 3B32 complex" EXACT [PMID:15979864] +is_a: GO:0043256 ! laminin complex +created_by: dph +creation_date: 2016-10-26T15:05:15Z + +[Term] +id: GO:0061802 +name: anterior cell cortex +namespace: cellular_component +def: "The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis." [GOC:15666355, GOC:17981131, GOC:dph, GOC:kmv] +is_a: GO:0099738 ! cell cortex region +created_by: dph +creation_date: 2016-11-06T22:54:21Z + +[Term] +id: GO:0061803 +name: posterior cell cortex +namespace: cellular_component +def: "The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis." [GOC:dph, GOC:kmv, PMID:15666355, PMID:17981131] +is_a: GO:0099738 ! cell cortex region +created_by: dph +creation_date: 2016-11-06T22:55:45Z + +[Term] +id: GO:0061804 +name: mitotic spindle formation (spindle phase one) +namespace: biological_process +def: "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase." [GOC:dph, GOC:vw, PMID:21920317] +synonym: "mitotic spindle elongation during mitotic prophase" EXACT [] +synonym: "mitotic spindle elongation during prophase" EXACT [] +synonym: "mitotic spindle elongation during prophase and prometaphase" EXACT [] +is_a: GO:0007052 ! mitotic spindle organization +intersection_of: GO:0007051 ! spindle organization +intersection_of: happens_during GO:0000088 ! mitotic prophase +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: happens_during GO:0000088 ! mitotic prophase +relationship: part_of GO:0000022 ! mitotic spindle elongation +relationship: part_of GO:0090307 ! mitotic spindle assembly +created_by: dph +creation_date: 2016-11-06T23:08:01Z + +[Term] +id: GO:0061805 +name: mitotic spindle elongation (spindle phase three) +namespace: biological_process +def: "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B." [GOC:dph, GOC:vw, PMID:21920317] +synonym: "mitotic anaphase spindle elongation" EXACT [] +synonym: "mitotic spindle elongation during anaphase" EXACT [] +synonym: "mitotic spindle elongation during mitotic anaphase" EXACT [] +is_a: GO:0007052 ! mitotic spindle organization +intersection_of: GO:0007051 ! spindle organization +intersection_of: happens_during GO:0000092 ! mitotic anaphase B +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: happens_during GO:0000092 ! mitotic anaphase B +relationship: part_of GO:0000022 ! mitotic spindle elongation +created_by: dph +creation_date: 2016-11-06T23:09:43Z + +[Term] +id: GO:0061806 +name: regulation of DNA recombination at centromere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA." [GOC:dph, GOC:mah, PMID:27697832] +synonym: "regulation of centromeric recombination" EXACT [GOC:mah] +is_a: GO:0000018 ! regulation of DNA recombination +created_by: dph +creation_date: 2016-11-10T15:17:11Z + +[Term] +id: GO:0061807 +name: positive regulation of DNA recombination at centromere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere." [GOC:dph, GOC:mah] +synonym: "positive regulation of centromeric recombination" EXACT [GOC:mah] +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:0061806 ! regulation of DNA recombination at centromere +created_by: dph +creation_date: 2016-11-10T15:20:04Z + +[Term] +id: GO:0061808 +name: negative regulation of DNA recombination at centromere +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere." [GOC:dph, GOC:mah] +synonym: "negative regulation of centromeric recombination" EXACT [GOC:dph] +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:0061806 ! regulation of DNA recombination at centromere +created_by: dph +creation_date: 2016-11-10T15:24:50Z + +[Term] +id: GO:0061809 +name: NAD+ nucleotidase, cyclic ADP-ribose generating +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity." [GOC:dph, GOC:pad, GOC:PARL, GOC:pde, PMID:11866528] +xref: EC:3.2.2.6 +xref: MetaCyc:NADNUCLEOSID-RXN +is_a: GO:0003953 ! NAD+ nucleosidase activity +relationship: has_part GO:0061811 ! ADP-ribosyl cyclase activity +relationship: has_part GO:0061812 ! cyclic ADP-ribose hydrolase +created_by: dph +creation_date: 2016-11-11T13:14:13Z + +[Term] +id: GO:0061810 +name: NAD glycohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate." [GOC:dph, GOC:pad, GOC:PARL, GOC:pde, PMID:11866528] +xref: EC:3.2.2.5 +is_a: GO:0003953 ! NAD+ nucleosidase activity +created_by: dph +creation_date: 2016-11-11T13:18:54Z + +[Term] +id: GO:0061811 +name: ADP-ribosyl cyclase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide." [GOC:dph, GOC:pad, GOC:PARL, PMID:11866528] +is_a: GO:0009975 ! cyclase activity +created_by: dph +creation_date: 2016-11-11T13:25:18Z + +[Term] +id: GO:0061812 +name: cyclic ADP-ribose hydrolase +namespace: molecular_function +def: "Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR)." [GOC:dph, GOC:pad, GOC:PARL, PMID:11866528] +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: dph +creation_date: 2016-11-11T13:32:43Z + +[Term] +id: GO:0061813 +name: obsolete ARID domain binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a ARID domain. The AT-rich interaction domain (ARID) is an ~100-amino acid DNA-binding module found in a large number of eukaryotic transcription factors." [GOC:dph, InterPro:IPR001606, PMID:18270511] +is_obsolete: true +created_by: dph +creation_date: 2016-11-11T13:57:55Z + +[Term] +id: GO:0061814 +name: condensin I complex +namespace: cellular_component +def: "A condensin complex that associates with chromosomes after nuclear envelope breakdown." [GOC:dph, PMID:21795393] +is_a: GO:0000796 ! condensin complex +created_by: dph +creation_date: 2016-11-23T10:34:33Z + +[Term] +id: GO:0061815 +name: ubiquitinyl hydrolase activity, acting on linear ubiquitin +namespace: molecular_function +def: "Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains." [GOC:dph, PMID:26503766, PMID:27702987] +synonym: "linear ubiquitin specific deubiquitinase activity" EXACT [] +synonym: "Met1 linkage specific DUB" EXACT [] +is_a: GO:0101005 ! ubiquitinyl hydrolase activity +created_by: dph +creation_date: 2016-11-28T13:58:44Z + +[Term] +id: GO:0061816 +name: proteaphagy +namespace: biological_process +def: "The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles." [GOC:dph, GOC:se, PMID:26670610, PMID:27477278] +is_a: GO:0035973 ! aggrephagy +created_by: dph +creation_date: 2016-12-01T20:21:28Z + +[Term] +id: GO:0061817 +name: endoplasmic reticulum-plasma membrane tethering +namespace: biological_process +def: "The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers." [GOC:dph, GOC:vw, PMID:23237950, PMID:26877082, PMID:27875684] +synonym: "ER-plasma membrane tethering" EXACT [GOC:dph] +is_a: GO:0051643 ! endoplasmic reticulum localization +is_a: GO:0140056 ! organelle localization by membrane tethering +created_by: dph +creation_date: 2016-12-05T14:43:58Z + +[Term] +id: GO:0061818 +name: tRNA folding +namespace: biological_process +def: "The process of assisting in the folding of tRNAs into the correct tertiary structure." [GOC:dph, PMID:27849601] +is_a: GO:0034337 ! RNA folding +created_by: dph +creation_date: 2016-12-13T15:54:40Z + +[Term] +id: GO:0061819 +name: telomeric DNA-containing double minutes formation +namespace: biological_process +def: "A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:14690602, PMID:2397458] +synonym: "TDMs formation" EXACT [] +is_a: GO:0000722 ! telomere maintenance via recombination +created_by: dph +creation_date: 2016-12-20T09:49:03Z + +[Term] +id: GO:0061820 +name: telomeric D-loop disassembly +namespace: biological_process +def: "A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:10338204, PMID:24012755] +is_a: GO:0090657 ! telomeric loop disassembly +created_by: dph + +[Term] +id: GO:0061821 +name: telomeric D-loop binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:19734539] +synonym: "telomeric Displacement-loop binding" EXACT [] +is_a: GO:0062037 ! D-loop DNA binding +created_by: dph + +[Term] +id: GO:0061822 +name: ciliary cap +namespace: cellular_component +def: "An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole." [PMID:25447994, PMID:27646273] +synonym: "spermatid ciliary cap" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium +created_by: dph +creation_date: 2017-01-14T14:14:11Z + +[Term] +id: GO:0061823 +name: ring centriole +namespace: cellular_component +def: "A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum." [PMID:25447994, PMID:4903810] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium +created_by: dph +creation_date: 2017-01-14T14:18:29Z + +[Term] +id: GO:0061824 +name: cytosolic ciliogenesis +namespace: biological_process +def: "The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm." [PMID:25447994, PMID:26654377] +synonym: "intracellular ciliogenesis" RELATED [] +is_a: GO:0060271 ! cilium assembly +created_by: dph +creation_date: 2017-01-14T14:24:17Z + +[Term] +id: GO:0061825 +name: podosome core +namespace: cellular_component +def: "The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell." [PMID:23158496] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0002102 ! podosome +created_by: dph +creation_date: 2017-01-14T14:42:45Z + +[Term] +id: GO:0061826 +name: podosome ring +namespace: cellular_component +def: "The ring structure surrounding the podosome core, containing proteins such as vinculin and talin." [PMID:23158496] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0002102 ! podosome +created_by: dph +creation_date: 2017-01-14T14:44:53Z + +[Term] +id: GO:0061827 +name: sperm head +namespace: cellular_component +def: "The part of the late spermatid or spermatozoon that contains the nucleus and acrosome." [PMID:22797892, PMID:24665388] +is_a: GO:0110165 ! cellular anatomical entity +created_by: dph +creation_date: 2017-01-15T10:39:00Z + +[Term] +id: GO:0061828 +name: apical tubulobulbar complex +namespace: cellular_component +def: "Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell." [PMID:20403871, PMID:22510523] +synonym: "apical TBC" EXACT [] +is_a: GO:0036284 ! tubulobulbar complex +created_by: dph +creation_date: 2017-01-15T10:41:00Z + +[Term] +id: GO:0061829 +name: basal tubulobulbar complex +namespace: cellular_component +def: "Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell." [PMID:20403871, PMID:22510523] +synonym: "basal TBC" EXACT [] +is_a: GO:0036284 ! tubulobulbar complex +created_by: dph +creation_date: 2017-01-15T10:42:31Z + +[Term] +id: GO:0061830 +name: concave side of sperm head +namespace: cellular_component +def: "The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species." [PMID:22332112, PMID:23403943, PMID:26990065] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0061827 ! sperm head + +[Term] +id: GO:0061831 +name: apical ectoplasmic specialization +namespace: cellular_component +def: "Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell." [GOC:aruk, GOC:bc, GOC:dph, PMID:22332112, PMID:23546604] +synonym: "apical ES" EXACT [] +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0061832 +name: basal ectoplasmic specialization +namespace: cellular_component +def: "Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell." [GOC:aruk, GOC:bc, GOC:dph, PMID:22332112, PMID:23546604] +synonym: "basal ES" EXACT [] +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0061833 +name: protein localization to tricellular tight junction +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction." [PMID:24889144] +is_a: GO:0150105 ! protein localization to cell-cell junction + +[Term] +id: GO:0061834 +name: actin filament branch point +namespace: cellular_component +def: "The part of an actin filament where the structure forks." [PMID:18256280] +synonym: "microfilament branch point" EXACT [GOC:dph] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005884 ! actin filament + +[Term] +id: GO:0061835 +name: ventral surface of cell +namespace: cellular_component +def: "The surface of a migrating cell that is in contact with the substratum or cell layer." [PMID:11598004] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009986 ! cell surface + +[Term] +id: GO:0061836 +name: intranuclear rod +namespace: cellular_component +def: "A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions." [PMID:28074884] +synonym: "intranuclear actin rod" EXACT [] +is_a: GO:0099512 ! supramolecular fiber + +[Term] +id: GO:0061837 +name: neuropeptide processing +namespace: biological_process +def: "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide." [PMID:12657671, PMID:17564681] +is_a: GO:0140448 ! signaling receptor ligand precursor processing + +[Term] +id: GO:0061838 +name: CENP-T-W-S-X complex +namespace: cellular_component +def: "A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization." [PMID:22304909, PMID:22304917] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000775 ! chromosome, centromeric region + +[Term] +id: GO:0061840 +name: high-affinity ferrous iron transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:bhm, PMID:9413439] +synonym: "high affinity ferrous uptake transmembrane transporter activity" EXACT [] +synonym: "high-affinity ferrous iron uptake transmembrane transporter activity" EXACT [] +is_a: GO:0015093 ! ferrous iron transmembrane transporter activity + +[Term] +id: GO:0061841 +name: high-affinity iron exporter complex +namespace: cellular_component +def: "A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment." [GOC:bhm, PMID:10608875, PMID:9413439] +comment: An example of this is FET5 in Saccharomyces cerevisiae (P43561) in PMID:9413439. +synonym: "FET5-FTH1 high affinity iron exporter complex" NARROW [] +synonym: "FET5-FTH1 high-affinity iron exporter complex" NARROW [] +synonym: "high affinity iron exporter complex" EXACT [] +xref: IntAct:EBI-12592993 +is_a: GO:1902495 ! transmembrane transporter complex +is_a: GO:1905862 ! ferroxidase complex +relationship: part_of GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0061842 +name: microtubule organizing center localization +namespace: biological_process +def: "Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell." [PMID:21281821] +synonym: "microtubule organizing center polarity" NARROW [] +synonym: "MTOC localization" EXACT [] +synonym: "MTOC polarity" NARROW [] +is_a: GO:0009987 ! cellular process +is_a: GO:0051179 ! localization + +[Term] +id: GO:0061843 +name: Sertoli cell barrier remodeling +namespace: biological_process +def: "The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle." [PMID:20534520, PMID:24467744] +synonym: "blood testis barrier restructuring" BROAD [] +synonym: "restructuring of blood-testis barrier" BROAD [] +synonym: "restructuring of BTB" BROAD [] +synonym: "restructuring of SCB" EXACT [] +synonym: "SCB remodeling" EXACT [] +synonym: "Sertoli cell barrier restructuring" EXACT [] +is_a: GO:0048771 ! tissue remodeling + +[Term] +id: GO:0061844 +name: antimicrobial humoral immune response mediated by antimicrobial peptide +namespace: biological_process +def: "An immune response against microbes mediated by anti-microbial peptides in body fluid." [PMID:15761415, PMID:24287494] +synonym: "antimicrobial peptide-mediated antimicrobial humoral response" EXACT [] +synonym: "peptide-mediated antimicrobial humoral response" BROAD [] +is_a: GO:0019730 ! antimicrobial humoral response + +[Term] +id: GO:0061845 +name: neuron projection branch point +namespace: cellular_component +def: "The location where a secondary projection arises from a neuron projection." [PMID:25586189] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043005 ! neuron projection + +[Term] +id: GO:0061846 +name: dendritic spine cytoplasm +namespace: cellular_component +def: "The region of the neuronal cytoplasm located in dendritic spines." [PMID:15673667] +is_a: GO:0032839 ! dendrite cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0043197 ! dendritic spine +relationship: part_of GO:0043197 ! dendritic spine + +[Term] +id: GO:0061847 +name: response to cholecystokinin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus." [PMID:14622258] +is_a: GO:0043434 ! response to peptide hormone + +[Term] +id: GO:0061848 +name: cellular response to cholecystokinin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus." [PMID:14622258] +is_a: GO:0061847 ! response to cholecystokinin +is_a: GO:0071375 ! cellular response to peptide hormone stimulus + +[Term] +id: GO:0061849 +name: telomeric G-quadruplex DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:16142245, PMID:9512530] +is_a: GO:0042162 ! telomeric DNA binding +is_a: GO:0051880 ! G-quadruplex DNA binding + +[Term] +id: GO:0061850 +name: growth cone leading edge +namespace: cellular_component +def: "That part of the growth cone which represents the distal part of the structure." [PMID:10797548] +is_a: GO:0031252 ! cell leading edge +intersection_of: GO:0031252 ! cell leading edge +intersection_of: part_of GO:0090725 ! peripheral region of growth cone +relationship: part_of GO:0090725 ! peripheral region of growth cone + +[Term] +id: GO:0061851 +name: leading edge of lamellipodium +namespace: cellular_component +def: "That part of the lamellipodium which represents the distal part of the structure." [PMID:22339865] +is_a: GO:0031252 ! cell leading edge +intersection_of: GO:0031252 ! cell leading edge +intersection_of: part_of GO:0030027 ! lamellipodium +relationship: part_of GO:0030027 ! lamellipodium + +[Term] +id: GO:0061852 +name: retrograte transporter complex, Golgi to ER +namespace: cellular_component +def: "Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles." [GOC:bhm, PMID:16093310] +comment: An example of this is ERV41 in Saccharomyces cerevisiae (Q04651) in PMID:16093310 (inferred from direct assay). +synonym: "ERV41-ERV46 retrograde receptor complex" NARROW [] +synonym: "retrograte receptor complex, Golgi to endoplasmic reticulum" EXACT [] +synonym: "retrograte receptor complex, Golgi to ER" EXACT [] +synonym: "retrograte transporter complex, Golgi to endoplasmic reticulum" EXACT [] +is_a: GO:1990351 ! transporter complex +created_by: dph +creation_date: 2017-02-28T13:56:56Z + +[Term] +id: GO:0061853 +name: regulation of neuroblast migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097402 ! neuroblast migration +relationship: regulates GO:0097402 ! neuroblast migration +created_by: dph +creation_date: 2017-03-08T18:17:07Z + +[Term] +id: GO:0061854 +name: positive regulation of neuroblast migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0061853 ! regulation of neuroblast migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097402 ! neuroblast migration +relationship: positively_regulates GO:0097402 ! neuroblast migration +created_by: dph +creation_date: 2017-03-08T18:22:30Z + +[Term] +id: GO:0061855 +name: negative regulation of neuroblast migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0061853 ! regulation of neuroblast migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097402 ! neuroblast migration +relationship: negatively_regulates GO:0097402 ! neuroblast migration +created_by: dph +creation_date: 2017-03-08T18:26:21Z + +[Term] +id: GO:0061856 +name: Golgi calcium ion transmembrane transport +namespace: biological_process +def: "A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore." [PMID:21811607] +is_a: GO:0032472 ! Golgi calcium ion transport +is_a: GO:0070588 ! calcium ion transmembrane transport +created_by: dph +creation_date: 2017-03-14T16:08:23Z + +[Term] +id: GO:0061857 +name: endoplasmic reticulum stress-induced pre-emptive quality control +namespace: biological_process +def: "The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome." [PMID:17129784, PMID:26565908] +synonym: "ER pQC" EXACT [] +synonym: "ER stress-indiced pre-emptive quality control" EXACT [] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +created_by: dph +creation_date: 2017-03-28T13:05:03Z + +[Term] +id: GO:0061860 +name: DNA clamp unloader activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex." [GOC:vw, PMID:23499004] +is_a: GO:0003677 ! DNA binding +is_a: GO:0016887 ! ATPase activity +relationship: part_of GO:0090618 ! DNA clamp unloading +created_by: dph +creation_date: 2017-04-03T11:49:46Z + +[Term] +id: GO:0061862 +name: cellular response to differentiation-inducing factor 2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus." [PMID:19684855] +synonym: "cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one" EXACT [] +synonym: "cellular response to DIF-2" RELATED [] +synonym: "cellular response to DIF2" RELATED [] +is_a: GO:0051716 ! cellular response to stimulus +is_a: GO:1905960 ! response to differentiation-inducing factor 2 +created_by: dph +creation_date: 2017-04-07T17:14:16Z + +[Term] +id: GO:0061863 +name: microtubule plus end polymerase +namespace: molecular_function +def: "Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers." [PMID:27872152] +is_a: GO:0016740 ! transferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0000226 ! microtubule cytoskeleton organization +created_by: dph +creation_date: 2017-04-07T17:36:57Z + +[Term] +id: GO:0061864 +name: basement membrane constituent secretion +namespace: biological_process +def: "The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell." [PMID:26610918, PMID:28228250] +is_a: GO:0070278 ! extracellular matrix constituent secretion +created_by: dph +creation_date: 2017-04-07T18:23:39Z + +[Term] +id: GO:0061865 +name: polarized secretion of basement membrane proteins in epithelium +namespace: biological_process +def: "The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium." [PMID:26610918, PMID:28228250] +is_a: GO:0061864 ! basement membrane constituent secretion +created_by: dph +creation_date: 2017-04-07T18:26:02Z + +[Term] +id: GO:0061866 +name: negative regulation of histone H3-S10 phosphorylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10." [PMID:27521428] +is_a: GO:0033128 ! negative regulation of histone phosphorylation +is_a: GO:0033137 ! negative regulation of peptidyl-serine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043987 ! histone H3-S10 phosphorylation +relationship: negatively_regulates GO:0043987 ! histone H3-S10 phosphorylation +created_by: dph +creation_date: 2017-04-07T18:45:51Z + +[Term] +id: GO:0061867 +name: establishment of mitotic spindle asymmetry +namespace: biological_process +def: "The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure." [PMID:26659188] +is_a: GO:0007052 ! mitotic spindle organization +created_by: dph +creation_date: 2017-04-28T12:39:13Z + +[Term] +id: GO:0061868 +name: hepatic stellate cell migration +namespace: biological_process +def: "The orderly movement of a hepatic stellate cell from one site to another." [PMID:24204762] +is_a: GO:0010761 ! fibroblast migration +created_by: dph +creation_date: 2017-05-01T13:01:40Z + +[Term] +id: GO:0061869 +name: regulation of hepatic stellate cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatic stellate cell migration." [PMID:24204762] +is_a: GO:0010762 ! regulation of fibroblast migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061868 ! hepatic stellate cell migration +relationship: regulates GO:0061868 ! hepatic stellate cell migration +created_by: dph +creation_date: 2017-05-01T13:04:20Z + +[Term] +id: GO:0061870 +name: positive regulation of hepatic stellate cell migration +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of hepatic stellate cell migration." [PMID:24204762] +is_a: GO:0010763 ! positive regulation of fibroblast migration +is_a: GO:0061869 ! regulation of hepatic stellate cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061868 ! hepatic stellate cell migration +relationship: positively_regulates GO:0061868 ! hepatic stellate cell migration +created_by: dph +creation_date: 2017-05-01T13:17:23Z + +[Term] +id: GO:0061871 +name: negative regulation of hepatic stellate cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration." [PMID:24204762] +is_a: GO:0010764 ! negative regulation of fibroblast migration +is_a: GO:0061869 ! regulation of hepatic stellate cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061868 ! hepatic stellate cell migration +relationship: negatively_regulates GO:0061868 ! hepatic stellate cell migration +created_by: dph +creation_date: 2017-05-01T13:20:51Z + +[Term] +id: GO:0061872 +name: hepatic stellate cell contraction +namespace: biological_process +def: "The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell." [PMID:24204762] +is_a: GO:0070252 ! actin-mediated cell contraction +created_by: dph +creation_date: 2017-05-01T13:25:18Z + +[Term] +id: GO:0061873 +name: regulation of hepatic stellate cell contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction." [PMID:24204762] +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061872 ! hepatic stellate cell contraction +relationship: regulates GO:0061872 ! hepatic stellate cell contraction +created_by: dph +creation_date: 2017-05-01T13:26:49Z + +[Term] +id: GO:0061874 +name: positive regulation of hepatic stellate cell contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction." [PMID:24204762] +is_a: GO:0061873 ! regulation of hepatic stellate cell contraction +is_a: GO:1903116 ! positive regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061872 ! hepatic stellate cell contraction +relationship: positively_regulates GO:0061872 ! hepatic stellate cell contraction +created_by: dph +creation_date: 2017-05-01T13:29:30Z + +[Term] +id: GO:0061875 +name: negative regulation of hepatic stellate cell contraction +namespace: biological_process +def: "Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction." [PMID:24204762] +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0061873 ! regulation of hepatic stellate cell contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061872 ! hepatic stellate cell contraction +relationship: negatively_regulates GO:0061872 ! hepatic stellate cell contraction +created_by: dph +creation_date: 2017-05-01T13:31:42Z + +[Term] +id: GO:0061880 +name: regulation of anterograde axonal transport of mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." [PMID:24302729] +synonym: "regulation of anterograde axon transport of mitochondria" EXACT [] +is_a: GO:1902513 ! regulation of organelle transport along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098957 ! anterograde axonal transport of mitochondrion +relationship: regulates GO:0098957 ! anterograde axonal transport of mitochondrion +created_by: dph +creation_date: 2017-05-30T14:15:46Z + +[Term] +id: GO:0061881 +name: positive regulation of anterograde axonal transport of mitochondrion +namespace: biological_process +def: "Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." [PMID:24302729] +synonym: "positive regulation of anterograde axon transport of mitochondria" EXACT [] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:0061880 ! regulation of anterograde axonal transport of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098957 ! anterograde axonal transport of mitochondrion +relationship: positively_regulates GO:0098957 ! anterograde axonal transport of mitochondrion +created_by: dph +creation_date: 2017-05-30T14:21:08Z + +[Term] +id: GO:0061882 +name: negative regulation of anterograde axonal transport of mitochondrion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." [PMID:24302729] +synonym: "negative regulation of anterograde axon transport of mitochondria" EXACT [] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0061880 ! regulation of anterograde axonal transport of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098957 ! anterograde axonal transport of mitochondrion +relationship: negatively_regulates GO:0098957 ! anterograde axonal transport of mitochondrion +created_by: dph +creation_date: 2017-05-30T14:25:16Z + +[Term] +id: GO:0061883 +name: clathrin-dependent endocytosis involved in vitellogenesis +namespace: biological_process +def: "A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition." [PMID:26265702] +synonym: "clathrin-dependent endocytosis involved in yolk formation" EXACT [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0072583 ! clathrin-dependent endocytosis +intersection_of: GO:0072583 ! clathrin-dependent endocytosis +intersection_of: part_of GO:0007296 ! vitellogenesis +relationship: part_of GO:0007296 ! vitellogenesis +created_by: dph +creation_date: 2017-05-30T14:41:21Z + +[Term] +id: GO:0061884 +name: regulation of mini excitatory postsynaptic potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse." [GOC:aruk, GOC:bc, PMID:20395454] +is_a: GO:0098815 ! modulation of excitatory postsynaptic potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098816 ! mini excitatory postsynaptic potential +relationship: regulates GO:0098816 ! mini excitatory postsynaptic potential +created_by: dph +creation_date: 2017-05-30T15:35:46Z + +[Term] +id: GO:0061885 +name: positive regulation of mini excitatory postsynaptic potential +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse." [GOC:aruk, GOC:bc, PMID:20395454] +is_a: GO:0061884 ! regulation of mini excitatory postsynaptic potential +is_a: GO:2000463 ! positive regulation of excitatory postsynaptic potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098816 ! mini excitatory postsynaptic potential +relationship: positively_regulates GO:0098816 ! mini excitatory postsynaptic potential +created_by: dph +creation_date: 2017-05-30T15:46:16Z + +[Term] +id: GO:0061886 +name: negative regulation of mini excitatory postsynaptic potential +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse." [GOC:aruk, GOC:bc, PMID:20395454] +is_a: GO:0061884 ! regulation of mini excitatory postsynaptic potential +is_a: GO:0090394 ! negative regulation of excitatory postsynaptic potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098816 ! mini excitatory postsynaptic potential +relationship: negatively_regulates GO:0098816 ! mini excitatory postsynaptic potential +created_by: dph +creation_date: 2017-05-30T15:50:08Z + +[Term] +id: GO:0061887 +name: reproduction of symbiont in host +namespace: biological_process +def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms, occurring within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:23460907, PMID:25713147] +is_a: GO:0000003 ! reproduction +is_a: GO:0044403 ! symbiotic process +created_by: dph +creation_date: 2017-06-01T18:07:47Z + +[Term] +id: GO:0061888 +name: regulation of astrocyte activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of astrocyte activation." [GOC:aruk, GOC:bc, PMID:20005821] +is_a: GO:0048710 ! regulation of astrocyte differentiation +is_a: GO:0050865 ! regulation of cell activation +is_a: GO:0150077 ! regulation of neuroinflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048143 ! astrocyte activation +relationship: regulates GO:0048143 ! astrocyte activation +created_by: dph +creation_date: 2017-06-01T22:26:29Z + +[Term] +id: GO:0061889 +name: negative regulation of astrocyte activation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of astrocyte activation." [GOC:aruk, GOC:bc, PMID:20005821] +is_a: GO:0048712 ! negative regulation of astrocyte differentiation +is_a: GO:0050866 ! negative regulation of cell activation +is_a: GO:0061888 ! regulation of astrocyte activation +is_a: GO:0150079 ! negative regulation of neuroinflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048143 ! astrocyte activation +relationship: negatively_regulates GO:0048143 ! astrocyte activation +created_by: dph +creation_date: 2017-06-01T22:29:43Z + +[Term] +id: GO:0061890 +name: positive regulation of astrocyte activation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of astrocyte activation." [GOC:aruk, GOC:bc, PMID:20005821] +is_a: GO:0048711 ! positive regulation of astrocyte differentiation +is_a: GO:0050867 ! positive regulation of cell activation +is_a: GO:0061888 ! regulation of astrocyte activation +is_a: GO:0150078 ! positive regulation of neuroinflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048143 ! astrocyte activation +relationship: positively_regulates GO:0048143 ! astrocyte activation +created_by: dph +creation_date: 2017-06-01T22:31:50Z + +[Term] +id: GO:0061891 +name: calcium ion sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+)." [PMID:16005298, PMID:17020874, PMID:28151650] +is_a: GO:0005509 ! calcium ion binding +is_a: GO:0140299 ! small molecule sensor activity +created_by: dph +creation_date: 2017-06-01T23:37:01Z + +[Term] +id: GO:0061896 +name: all-trans retinol 3,4-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin]." [PMID:27059013] +xref: RHEA:50292 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2017-06-12T14:49:30Z + +[Term] +id: GO:0061897 +name: all-trans retinal 3,4-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin]." [PMID:27059013] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2017-06-12T14:56:58Z + +[Term] +id: GO:0061898 +name: all-trans retinoic acid 3,4-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin]." [PMID:27059013] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2017-06-12T15:01:23Z + +[Term] +id: GO:0061899 +name: 11-cis-retinal 3,4-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin]." [PMID:27059013] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2017-06-12T15:03:57Z + +[Term] +id: GO:0061900 +name: glial cell activation +namespace: biological_process +def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082] +is_a: GO:0001775 ! cell activation +relationship: part_of GO:0150076 ! neuroinflammatory response +created_by: dph +creation_date: 2017-06-13T13:06:23Z + +[Term] +id: GO:0061901 +name: regulation of 1-phosphatidylinositol-3-kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity." [GOC:aruk, GOC:bc, PMID:18723082] +is_a: GO:0010511 ! regulation of phosphatidylinositol biosynthetic process +is_a: GO:0043551 ! regulation of phosphatidylinositol 3-kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +relationship: regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +created_by: dph +creation_date: 2017-06-22T19:34:56Z + +[Term] +id: GO:0061902 +name: negative regulation of 1-phosphatidylinositol-3-kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity." [GOC:aruk, GOC:bc, PMID:18723082] +is_a: GO:0010512 ! negative regulation of phosphatidylinositol biosynthetic process +is_a: GO:0043553 ! negative regulation of phosphatidylinositol 3-kinase activity +is_a: GO:0061901 ! regulation of 1-phosphatidylinositol-3-kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +relationship: negatively_regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +created_by: dph +creation_date: 2017-06-22T19:51:34Z + +[Term] +id: GO:0061903 +name: positive regulation of 1-phosphatidylinositol-3-kinase activity +namespace: biological_process +def: "Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity." [GOC:aruk, GOC:bc, PMID:18723082] +is_a: GO:0010513 ! positive regulation of phosphatidylinositol biosynthetic process +is_a: GO:0043552 ! positive regulation of phosphatidylinositol 3-kinase activity +is_a: GO:0061901 ! regulation of 1-phosphatidylinositol-3-kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +relationship: positively_regulates GO:0016303 ! 1-phosphatidylinositol-3-kinase activity +created_by: dph +creation_date: 2017-06-22T19:54:53Z + +[Term] +id: GO:0061906 +name: autophagosome localization +namespace: biological_process +def: "Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell." [PMID:26763909] +is_a: GO:0051640 ! organelle localization +created_by: dph +creation_date: 2017-06-28T17:27:57Z + +[Term] +id: GO:0061907 +name: negative regulation of AMPA receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity." [GOC:aruk, GOC:bc, PMID:20739563] +is_a: GO:1900450 ! negative regulation of glutamate receptor signaling pathway +is_a: GO:2000272 ! negative regulation of signaling receptor activity +is_a: GO:2000311 ! regulation of AMPA receptor activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004971 ! AMPA glutamate receptor activity +relationship: negatively_regulates GO:0004971 ! AMPA glutamate receptor activity +created_by: dph +creation_date: 2017-06-29T11:55:11Z + +[Term] +id: GO:0061908 +name: phagophore +namespace: cellular_component +def: "A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle." [PMID:22664348, PMID:24201109] +synonym: "isolation membrane" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: dph +creation_date: 2017-06-29T16:59:19Z + +[Term] +id: GO:0061909 +name: autophagosome-lysosome fusion +namespace: biological_process +def: "The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome." [PMID:28077293] +synonym: "autophagosome fusion" BROAD [] +synonym: "autophagosome-vacuole fusion" EXACT [] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0016236 ! macroautophagy +created_by: dph +creation_date: 2017-06-29T17:07:52Z + +[Term] +id: GO:0061910 +name: autophagosome-endosome fusion +namespace: biological_process +def: "The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome." [PMID:24219988] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0016236 ! macroautophagy +created_by: dph +creation_date: 2017-06-29T17:10:43Z + +[Term] +id: GO:0061911 +name: amphisome-lysosome fusion +namespace: biological_process +def: "The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome." [PMID:24219988] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0016236 ! macroautophagy +created_by: dph +creation_date: 2017-07-05T18:54:52Z + +[Term] +id: GO:0061912 +name: selective autophagy +namespace: biological_process +def: "The macroautophagy process in which specific structures are targeted by the autophagy process." [PMID:20484971, PMID:21997368, PMID:22966490] +is_a: GO:0016236 ! macroautophagy +created_by: dph +creation_date: 2017-07-07T17:27:37Z + +[Term] +id: GO:0061913 +name: positive regulation of growth plate cartilage chondrocyte proliferation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population." [PMID:19264869] +is_a: GO:0003420 ! regulation of growth plate cartilage chondrocyte proliferation +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0046622 ! positive regulation of organ growth +is_a: GO:0061036 ! positive regulation of cartilage development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1903012 ! positive regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +relationship: positively_regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +created_by: dph +creation_date: 2017-07-10T17:31:09Z + +[Term] +id: GO:0061914 +name: negative regulation of growth plate cartilage chondrocyte proliferation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population." [PMID:19264869] +is_a: GO:0003420 ! regulation of growth plate cartilage chondrocyte proliferation +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0046621 ! negative regulation of organ growth +is_a: GO:0061037 ! negative regulation of cartilage development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1903011 ! negative regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +relationship: negatively_regulates GO:0003419 ! growth plate cartilage chondrocyte proliferation +created_by: dph +creation_date: 2017-07-10T17:39:17Z + +[Term] +id: GO:0061915 +name: actin fusion focus localization +namespace: biological_process +def: "Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion." [PMID:28410370] +synonym: "actin fusion focus localisation" EXACT [] +is_a: GO:0051641 ! cellular localization +created_by: dph +creation_date: 2017-07-10T18:11:47Z + +[Term] +id: GO:0061916 +name: leading edge of axonal growth cone +namespace: cellular_component +def: "That part of the axonal growth cone which represents the distal part of the structure." [PMID:16098134] +synonym: "axonal growth cone leading edge" EXACT [] +synonym: "distal tip of axonal growth cone" EXACT [] +is_a: GO:0061850 ! growth cone leading edge +intersection_of: GO:0031252 ! cell leading edge +intersection_of: part_of GO:0044295 ! axonal growth cone +intersection_of: part_of GO:0090725 ! peripheral region of growth cone +relationship: part_of GO:0044295 ! axonal growth cone +created_by: dph +creation_date: 2017-07-10T19:17:21Z + +[Term] +id: GO:0061917 +name: leading edge of dendritic growth cone +namespace: cellular_component +def: "That part of the dendritic growth cone which represents the distal part of the structure." [PMID:16098134] +synonym: "dendritic growth cone leading edge" EXACT [] +synonym: "distal tip of dendritic growth cone" EXACT [] +is_a: GO:0061850 ! growth cone leading edge +intersection_of: GO:0031252 ! cell leading edge +intersection_of: part_of GO:0044294 ! dendritic growth cone +intersection_of: part_of GO:0090725 ! peripheral region of growth cone +relationship: part_of GO:0044294 ! dendritic growth cone +created_by: dph +creation_date: 2017-07-10T19:25:23Z + +[Term] +id: GO:0061919 +name: process utilizing autophagic mechanism +namespace: biological_process +def: "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway." [PMID:21997368, PMID:22966490, PMID:28596378] +subset: gocheck_do_not_annotate +is_a: GO:0009987 ! cellular process +created_by: dph +creation_date: 2017-07-13T19:42:14Z + +[Term] +id: GO:0061920 +name: protein propionyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide." [PMID:17267393] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dph +creation_date: 2017-08-02T13:35:22Z + +[Term] +id: GO:0061921 +name: peptidyl-lysine propionylation +namespace: biological_process +def: "The propionylation of peptidyl-lysine." [PMID:17267393] +is_a: GO:0043543 ! protein acylation +created_by: dph +creation_date: 2017-08-02T13:37:14Z + +[Term] +id: GO:0061922 +name: histone propionyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone." [PMID:17267393] +is_a: GO:0061920 ! protein propionyltransferase activity +created_by: dph +creation_date: 2017-08-02T13:38:50Z + +[Term] +id: GO:0061923 +name: (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene." [PMID:27862766] +synonym: "protoillud-7-ene synthase activity" RELATED [] +is_a: GO:0010334 ! sesquiterpene synthase activity +created_by: dph +creation_date: 2017-08-02T15:48:21Z + +[Term] +id: GO:0061924 +name: regulation of formation of radial glial scaffolds +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells." [PMID:22076441] +synonym: "regulation of Bergmann fiber biosynthesis" RELATED [] +synonym: "regulation of Bergmann fiber formation" RELATED [] +synonym: "regulation of radial glial scaffold formation" EXACT [] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0021943 ! formation of radial glial scaffolds +relationship: regulates GO:0021943 ! formation of radial glial scaffolds +created_by: dph +creation_date: 2017-08-02T16:17:31Z + +[Term] +id: GO:0061925 +name: negative regulation of formation of radial glial scaffolds +namespace: biological_process +def: "Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells." [PMID:22076441] +synonym: "negative regulation of Bergmann fiber biosynthesis" RELATED [] +synonym: "negative regulation of Bergmann fiber formation" RELATED [] +synonym: "negative regulation of radial glial scaffold formation" EXACT [] +is_a: GO:0010771 ! negative regulation of cell morphogenesis involved in differentiation +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:0061924 ! regulation of formation of radial glial scaffolds +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021943 ! formation of radial glial scaffolds +relationship: negatively_regulates GO:0021943 ! formation of radial glial scaffolds +created_by: dph +creation_date: 2017-08-02T16:24:27Z + +[Term] +id: GO:0061926 +name: positive regulation of formation of radial glial scaffolds +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds." [PMID:22076441] +synonym: "positive regulation of Bergmann fiber biosynthesis" RELATED [] +synonym: "positive regulation of Bergmann fiber formation" RELATED [] +synonym: "positive regulation of radial glial scaffold formation" EXACT [] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:0061924 ! regulation of formation of radial glial scaffolds +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0021943 ! formation of radial glial scaffolds +relationship: positively_regulates GO:0021943 ! formation of radial glial scaffolds +created_by: dph +creation_date: 2017-08-02T16:29:37Z + +[Term] +id: GO:0061927 +name: TOC-TIC supercomplex I +namespace: cellular_component +def: "The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110." [PMID:28745032] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0009507 ! chloroplast +created_by: dph +creation_date: 2017-08-28T13:18:20Z + +[Term] +id: GO:0061928 +name: glutathione specific gamma-glutamylcyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine." [PMID:23070364, PMID:27913623] +xref: EC:4.3.2.7 +is_a: GO:0016842 ! amidine-lyase activity +created_by: dph +creation_date: 2017-08-29T14:55:30Z + +[Term] +id: GO:0061929 +name: gamma-glutamylaminecyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline." [PMID:20110353, PMID:6107907] +xref: EC:4.3.2.8 +is_a: GO:0016842 ! amidine-lyase activity +created_by: dph +creation_date: 2017-08-29T14:57:39Z + +[Term] +id: GO:0061930 +name: regulation of erythrocyte enucleation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of erythrocyte enucleation." [PMID:25241935] +is_a: GO:0045646 ! regulation of erythrocyte differentiation +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1903429 ! regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043131 ! erythrocyte enucleation +relationship: regulates GO:0043131 ! erythrocyte enucleation +created_by: dph +creation_date: 2017-09-05T12:48:05Z + +[Term] +id: GO:0061931 +name: positive regulation of erythrocyte enucleation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of erythrocyte enucleation." [PMID:25241935] +is_a: GO:0045648 ! positive regulation of erythrocyte differentiation +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0061930 ! regulation of erythrocyte enucleation +is_a: GO:1903431 ! positive regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043131 ! erythrocyte enucleation +relationship: positively_regulates GO:0043131 ! erythrocyte enucleation +created_by: dph +creation_date: 2017-09-05T12:57:33Z + +[Term] +id: GO:0061932 +name: negative regulation of erythrocyte enucleation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of erythrocyte enucleation." [PMID:25241935] +is_a: GO:0045647 ! negative regulation of erythrocyte differentiation +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0061930 ! regulation of erythrocyte enucleation +is_a: GO:1903430 ! negative regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043131 ! erythrocyte enucleation +relationship: negatively_regulates GO:0043131 ! erythrocyte enucleation +created_by: dph +creation_date: 2017-09-05T13:00:15Z + +[Term] +id: GO:0061934 +name: regulation of adenine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an adenine biosynthetic process." [PMID:19933844] +is_a: GO:0006141 ! regulation of purine nucleobase metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046084 ! adenine biosynthetic process +relationship: regulates GO:0046084 ! adenine biosynthetic process +created_by: dph +creation_date: 2017-09-05T14:58:46Z + +[Term] +id: GO:0061935 +name: fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes +namespace: biological_process +def: "The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes." [GOC:dph] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045026 ! plasma membrane fusion +relationship: part_of GO:0009677 ! double fertilization forming two zygotes +created_by: dph +creation_date: 2017-09-05T18:38:08Z + +[Term] +id: GO:0061936 +name: fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm +namespace: biological_process +def: "The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm." [PMID:21123745] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045026 ! plasma membrane fusion +relationship: part_of GO:0009567 ! double fertilization forming a zygote and endosperm +created_by: dph +creation_date: 2017-09-05T18:43:24Z + +[Term] +id: GO:0061938 +name: protein localization to somatodendritic compartment +namespace: biological_process +def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993] +synonym: "somatodendritic protein localization" EXACT [] +is_a: GO:0008104 ! protein localization +created_by: dph +creation_date: 2017-09-08T13:22:26Z + +[Term] +id: GO:0061939 +name: c-di-GMP signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal." [PMID:22864416, PMID:28057864] +synonym: "3',5'-cyclic di-GMP signaling" EXACT [] +synonym: "cyclic di-(3':5')-guanosine monophosphate signaling" EXACT [] +synonym: "cyclic di-GMP signaling" EXACT [] +synonym: "cyclic diguanylate signaling" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +created_by: dph +creation_date: 2017-09-14T18:59:04Z + +[Term] +id: GO:0061940 +name: regulation of c-di-GMP signaling +namespace: biological_process +def: "Any process that modulates the rate frequency or extent of c-di-GMP signaling." [PMID:22864416] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061939 ! c-di-GMP signaling +relationship: regulates GO:0061939 ! c-di-GMP signaling +created_by: dph +creation_date: 2017-09-14T19:07:41Z + +[Term] +id: GO:0061941 +name: positive regulation of c-di-GMP signaling +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of c-di-GMP signaling." [PMID:22864416] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0061940 ! regulation of c-di-GMP signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061939 ! c-di-GMP signaling +relationship: positively_regulates GO:0061939 ! c-di-GMP signaling +created_by: dph +creation_date: 2017-09-14T19:11:15Z + +[Term] +id: GO:0061942 +name: negative regulation of c-di-GMP signaling +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of c-di-GMP signaling." [PMID:22864416] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0061940 ! regulation of c-di-GMP signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061939 ! c-di-GMP signaling +relationship: negatively_regulates GO:0061939 ! c-di-GMP signaling +created_by: dph +creation_date: 2017-09-14T19:13:44Z + +[Term] +id: GO:0061944 +name: negative regulation of protein K48-linked ubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation." [GOC:BHF, GOC:rph, PMID:23460740] +is_a: GO:0061945 ! regulation of protein K48-linked ubiquitination +is_a: GO:1902915 ! negative regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070936 ! protein K48-linked ubiquitination +relationship: negatively_regulates GO:0070936 ! protein K48-linked ubiquitination +created_by: dph +creation_date: 2017-09-22T11:37:18Z + +[Term] +id: GO:0061945 +name: regulation of protein K48-linked ubiquitination +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation." [PMID:23460740] +is_a: GO:1902914 ! regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070936 ! protein K48-linked ubiquitination +relationship: regulates GO:0070936 ! protein K48-linked ubiquitination +created_by: dph +creation_date: 2017-09-22T11:45:43Z + +[Term] +id: GO:0061948 +name: premature acrosome loss +namespace: biological_process +def: "The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents." [PMID:19153666, PMID:21380641, PMID:26655718] +comment: If the release of the acrosome content when the sperm reaches to the zona pellucida, consider using acrosome reaction. +synonym: "spontaneous acrosome loss" EXACT [] +is_a: GO:0022414 ! reproductive process +created_by: dph +creation_date: 2017-10-25T17:46:55Z + +[Term] +id: GO:0061949 +name: regulation of premature acrosome loss +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents." [PMID:22228629, PMID:23430248] +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061948 ! premature acrosome loss +relationship: regulates GO:0061948 ! premature acrosome loss +created_by: dph +creation_date: 2017-10-25T17:51:32Z + +[Term] +id: GO:0061950 +name: negative regulation of premature acrosome loss +namespace: biological_process +def: "Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents." [PMID:22228629, PMID:23430248] +synonym: "negative regulation of spontaneous acrosome loss" EXACT [] +is_a: GO:0061949 ! regulation of premature acrosome loss +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061948 ! premature acrosome loss +relationship: negatively_regulates GO:0061948 ! premature acrosome loss +created_by: dph +creation_date: 2017-10-25T17:56:47Z + +[Term] +id: GO:0061951 +name: establishment of protein localization to plasma membrane +namespace: biological_process +def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw] +is_a: GO:0072659 ! protein localization to plasma membrane +is_a: GO:0090150 ! establishment of protein localization to membrane +created_by: dph +creation_date: 2017-10-26T12:55:15Z + +[Term] +id: GO:0061952 +name: midbody abscission +namespace: biological_process +def: "The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells." [PMID:12737809, PMID:29903934] +synonym: "cell separation during cytokinesis" EXACT [] +synonym: "cytokinetic abscission" EXACT [] +is_a: GO:0061024 ! membrane organization +is_a: GO:1902410 ! mitotic cytokinetic process +created_by: dph +creation_date: 2017-11-07T19:44:37Z + +[Term] +id: GO:0061953 +name: mRNA (adenine-N1-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA." [PMID:29072297] +is_a: GO:0008174 ! mRNA methyltransferase activity +created_by: dph +creation_date: 2017-11-08T13:26:35Z + +[Term] +id: GO:0061954 +name: positive regulation of actin filament polymerization involved in sperm capacitation +namespace: biological_process +def: "Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction." [PMID:15749953, PMID:25966627, PMID:26514336, PMID:27178669] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0030838 ! positive regulation of actin filament polymerization +intersection_of: GO:0065007 ! biological regulation +intersection_of: part_of GO:0048240 ! sperm capacitation +intersection_of: positively_regulates GO:0030041 ! actin filament polymerization +relationship: part_of GO:0048240 ! sperm capacitation +created_by: dph +creation_date: 2017-11-10T19:40:00Z + +[Term] +id: GO:0061955 +name: positive regulation of actin filament depolymerization involved in acrosome reaction +namespace: biological_process +def: "Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse." [PMID:20937821] +is_a: GO:0022414 ! reproductive process +is_a: GO:0030836 ! positive regulation of actin filament depolymerization +intersection_of: GO:0065007 ! biological regulation +intersection_of: part_of GO:0007340 ! acrosome reaction +intersection_of: positively_regulates GO:0030042 ! actin filament depolymerization +relationship: part_of GO:0007340 ! acrosome reaction +created_by: dph +creation_date: 2017-11-10T19:43:18Z + +[Term] +id: GO:0061956 +name: penetration of cumulus oophorus +namespace: biological_process +def: "The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm." [PMID:21380641] +synonym: "penetration of cumulus cells layer" EXACT [] +synonym: "penetration of cumulus mass" EXACT [] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007338 ! single fertilization +created_by: dph +creation_date: 2017-11-10T20:14:18Z + +[Term] +id: GO:0061957 +name: NVT complex +namespace: cellular_component +def: "A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1." [PMID:26365378] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2017-12-01T17:01:17Z + +[Term] +id: GO:0061959 +name: response to (R)-carnitine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus." [PMID:28102299] +synonym: "response to L-carnitine" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug +created_by: dph +creation_date: 2018-01-19T13:31:39Z + +[Term] +id: GO:0061960 +name: regulation of heme oxygenase activity +namespace: biological_process +def: "Any process that modulates the frequency, or rate of heme oxygenase activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24844779] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0004392 ! heme oxygenase (decyclizing) activity +relationship: regulates GO:0004392 ! heme oxygenase (decyclizing) activity +created_by: dph +creation_date: 2018-01-22T20:24:06Z + +[Term] +id: GO:0061961 +name: positive regulation of heme oxygenase activity +namespace: biological_process +def: "Any process that activates or increases the frequency or rate of heme oxygenase activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24844779] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:0061960 ! regulation of heme oxygenase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0004392 ! heme oxygenase (decyclizing) activity +relationship: positively_regulates GO:0004392 ! heme oxygenase (decyclizing) activity +created_by: dph +creation_date: 2018-01-22T20:32:05Z + +[Term] +id: GO:0061962 +name: negative regulation of heme oxygenase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24844779] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:0061960 ! regulation of heme oxygenase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0004392 ! heme oxygenase (decyclizing) activity +relationship: negatively_regulates GO:0004392 ! heme oxygenase (decyclizing) activity +created_by: dph +creation_date: 2018-01-22T20:37:03Z + +[Term] +id: GO:0061963 +name: regulation of entry into reproductive diapause +namespace: biological_process +def: "Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:ha, PMID:27689881] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0055116 ! entry into reproductive diapause +relationship: regulates GO:0055116 ! entry into reproductive diapause +created_by: dph +creation_date: 2018-02-05T15:02:16Z + +[Term] +id: GO:0061964 +name: negative regulation of entry into reproductive diapause +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:ha, PMID:27689881] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0061963 ! regulation of entry into reproductive diapause +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0055116 ! entry into reproductive diapause +relationship: negatively_regulates GO:0055116 ! entry into reproductive diapause +created_by: dph +creation_date: 2018-02-05T15:04:33Z + +[Term] +id: GO:0061965 +name: positive regulation of entry into reproductive diapause +namespace: biological_process +def: "Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:ha, PMID:27689881] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0061963 ! regulation of entry into reproductive diapause +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0055116 ! entry into reproductive diapause +relationship: positively_regulates GO:0055116 ! entry into reproductive diapause +created_by: dph +creation_date: 2018-02-05T15:06:51Z + +[Term] +id: GO:0061966 +name: establishment of left/right asymmetry +namespace: biological_process +def: "The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves." [GOC:BHF, PMID:18629866] +is_a: GO:0007368 ! determination of left/right symmetry +created_by: dph +creation_date: 2018-02-12T16:27:20Z + +[Term] +id: GO:0061967 +name: establishment of left sidedness +namespace: biological_process +def: "The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side." [GOC:18629866, GOC:BHF] +is_a: GO:0061966 ! establishment of left/right asymmetry +created_by: dph +creation_date: 2018-02-12T16:32:41Z + +[Term] +id: GO:0061968 +name: maintenance of left/right asymmetry +namespace: biological_process +def: "The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves." [GOC:BHF, PMID:18629866] +is_a: GO:0007389 ! pattern specification process +created_by: dph +creation_date: 2018-02-12T16:38:47Z + +[Term] +id: GO:0061969 +name: maintenance of left sidedness +namespace: biological_process +def: "The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves." [GOC:BHF, PMID:18629866] +is_a: GO:0061968 ! maintenance of left/right asymmetry +created_by: dph +creation_date: 2018-02-12T16:41:30Z + +[Term] +id: GO:0061970 +name: maintenance of right sidedness +namespace: biological_process +def: "The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves." [GOC:BHF, PMID:18629866] +is_a: GO:0061968 ! maintenance of left/right asymmetry +created_by: dph +creation_date: 2018-02-12T16:45:33Z + +[Term] +id: GO:0061971 +name: replacement bone morphogenesis +namespace: biological_process +def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [DOI:10.1002/(SICI)1097-4687(199608)229\:2<121\:\:AID-JMOR1>3.0.CO;2-4] +is_a: GO:0060349 ! bone morphogenesis +created_by: dph +creation_date: 2018-02-12T18:10:59Z + +[Term] +id: GO:0061972 +name: dermal bone morphogenesis +namespace: biological_process +def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632] +is_a: GO:0061973 ! membrane bone morphogenesis +created_by: dph +creation_date: 2018-02-12T18:16:21Z + +[Term] +id: GO:0061973 +name: membrane bone morphogenesis +namespace: biological_process +def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374] +is_a: GO:0060349 ! bone morphogenesis +created_by: dph +creation_date: 2018-02-12T18:21:09Z + +[Term] +id: GO:0061974 +name: perichondral bone morphogenesis +namespace: biological_process +def: "The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone." [PMID:21901110] +is_a: GO:0060350 ! endochondral bone morphogenesis +is_a: GO:0061973 ! membrane bone morphogenesis +created_by: dph +creation_date: 2018-02-12T18:26:10Z + +[Term] +id: GO:0061975 +name: articular cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure." [PMID:20097540, PMID:20679519] +synonym: "articular cartilage of joint development" EXACT [] +is_a: GO:0051216 ! cartilage development +created_by: dph +creation_date: 2018-02-12T19:57:31Z + +[Term] +id: GO:0061976 +name: temporomandibular joint articular cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure." [PMID:20679519] +is_a: GO:0061975 ! articular cartilage development +created_by: dph +creation_date: 2018-02-12T20:01:00Z + +[Term] +id: GO:0061977 +name: hip joint articular cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure." [PMID:20097540] +is_a: GO:0061975 ! articular cartilage development +created_by: dph +creation_date: 2018-02-12T20:03:22Z + +[Term] +id: GO:0061978 +name: mandibular condyle articular cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure." [PMID:20679519] +is_a: GO:0061976 ! temporomandibular joint articular cartilage development +created_by: dph +creation_date: 2018-02-12T20:04:49Z + +[Term] +id: GO:0061979 +name: femoral head articular cartilage development +namespace: biological_process +def: "The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure." [PMID:20097540] +is_a: GO:0061977 ! hip joint articular cartilage development +created_by: dph +creation_date: 2018-02-12T20:06:21Z + +[Term] +id: GO:0061980 +name: regulatory RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme." [PMID:14622403, PMID:23475961] +is_a: GO:0003723 ! RNA binding +created_by: dph +creation_date: 2018-02-13T21:46:08Z + +[Term] +id: GO:0061981 +name: 3-hydroxykynureninase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine." [PMID:17300176] +xref: RHEA:25143 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances +created_by: dph +creation_date: 2018-02-14T16:12:49Z + +[Term] +id: GO:0061982 +name: meiosis I cell cycle process +namespace: biological_process +def: "A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs." [PMID:29385397] +synonym: "first meiotic cell division" EXACT [PMID:29385397] +is_a: GO:1903046 ! meiotic cell cycle process +created_by: dph +creation_date: 2018-02-14T22:27:20Z + +[Term] +id: GO:0061983 +name: meiosis II cell cycle process +namespace: biological_process +def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397] +synonym: "second meiotic division" EXACT [PMID:29385397] +is_a: GO:1903046 ! meiotic cell cycle process +created_by: dph +creation_date: 2018-02-14T22:37:44Z + +[Term] +id: GO:0061984 +name: catabolite repression +namespace: biological_process +def: "A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources." [GOC:dph, PMID:29197127, PMID:29295552] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0031670 ! cellular response to nutrient +created_by: dph +creation_date: 2018-02-15T16:34:14Z + +[Term] +id: GO:0061985 +name: carbon catabolite repression +namespace: biological_process +def: "A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources." [PMID:29295552] +is_a: GO:0061984 ! catabolite repression +created_by: dph +creation_date: 2018-02-15T16:49:48Z + +[Term] +id: GO:0061986 +name: negative regulation of transcription by glucose +namespace: biological_process +def: "Any process involving glucose that decreases the frequency, rate or extent or transcription." [PMID:11875061] +is_a: GO:0046015 ! regulation of transcription by glucose +created_by: dph +creation_date: 2018-02-15T17:39:14Z + +[Term] +id: GO:0061987 +name: negative regulation of transcription from RNA polymerase II promoter by glucose +namespace: biological_process +def: "Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter." [PMID:11875061] +is_a: GO:0000430 ! regulation of transcription from RNA polymerase II promoter by glucose +is_a: GO:0061986 ! negative regulation of transcription by glucose +created_by: dph +creation_date: 2018-02-15T17:48:00Z + +[Term] +id: GO:0061988 +name: karyosome formation +namespace: biological_process +def: "The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome." [PMID:19696886] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0061982 ! meiosis I cell cycle process +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +relationship: part_of GO:0007276 ! gamete generation +created_by: dph +creation_date: 2018-02-15T21:24:08Z + +[Term] +id: GO:0061989 +name: sperm karyosome formation +namespace: biological_process +def: "The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome." [PMID:19696886] +is_a: GO:0061988 ! karyosome formation +relationship: part_of GO:0007283 ! spermatogenesis +created_by: dph +creation_date: 2018-02-15T21:29:47Z + +[Term] +id: GO:0061990 +name: beta-ketodecanoyl-[acyl-carrier-protein] synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2." [EC:2.3.1.207, PMID:22753057] +xref: MetaCyc:RXN-13613 +is_a: GO:0016415 ! octanoyltransferase activity +created_by: dph +creation_date: 2018-02-15T22:29:03Z + +[Term] +id: GO:0061992 +name: ATP-dependent chaperone mediated protein folding +namespace: biological_process +def: "The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis." [PMID:18311152] +is_a: GO:0061077 ! chaperone-mediated protein folding +created_by: dph +creation_date: 2018-02-15T23:34:28Z + +[Term] +id: GO:0061993 +name: calcium:proton antiporter complex +namespace: cellular_component +def: "A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in)." [GOC:bhm, PMID:19098009, PMID:28645169] +synonym: "CAX1 homodimer" NARROW [GOC:bhm] +synonym: "CAX1-CAX3 complex" NARROW [GOC:bhm] +synonym: "CAX3 homodimer" NARROW [GOC:bhm] +xref: IntAct:EBI-16693477 +xref: IntAct:EBI-16710427 +xref: IntAct:EBI-2292448 +is_a: GO:1902495 ! transmembrane transporter complex +created_by: dph +creation_date: 2018-02-16T02:17:10Z + +[Term] +id: GO:0061994 +name: ATP-dependent protein-nucleic acid complex displacement activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate coupled to the displacement of proteins or protein complexes from nucleic acid, sometimes in a 'wire stripping' fashion." [PMID:18593879] +is_a: GO:0008094 ! DNA-dependent ATPase activity +created_by: dph +creation_date: 2018-02-16T15:42:22Z + +[Term] +id: GO:0061995 +name: ATP-dependent protein-DNA complex displacement activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate coupled to the displacement of proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion." [PMID:18593879] +is_a: GO:0061994 ! ATP-dependent protein-nucleic acid complex displacement activity +created_by: dph +creation_date: 2018-02-16T15:46:47Z + +[Term] +id: GO:0061999 +name: regulation of cardiac endothelial to mesenchymal transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +relationship: regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +created_by: dph +creation_date: 2018-02-16T16:26:51Z + +[Term] +id: GO:0062000 +name: positive regulation of cardiac endothelial to mesenchymal transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0061999 ! regulation of cardiac endothelial to mesenchymal transition +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +relationship: positively_regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +created_by: dph +creation_date: 2018-02-16T16:31:06Z + +[Term] +id: GO:0062001 +name: negative regulation of cardiac endothelial to mesenchymal transition +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0061999 ! regulation of cardiac endothelial to mesenchymal transition +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +relationship: negatively_regulates GO:0140074 ! cardiac endothelial to mesenchymal transition +created_by: dph +creation_date: 2018-02-16T16:36:48Z + +[Term] +id: GO:0062002 +name: regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +namespace: biological_process +def: "Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity." [PMID:23407971] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0051336 ! regulation of hydrolase activity +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +relationship: regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +created_by: dph +creation_date: 2018-02-26T13:16:39Z + +[Term] +id: GO:0062003 +name: negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +namespace: biological_process +def: "Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity." [PMID:23407971] +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0062002 ! regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +relationship: negatively_regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +created_by: dph +creation_date: 2018-02-26T13:23:20Z + +[Term] +id: GO:0062009 +name: secondary palate development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences." [PMID:28784960] +is_a: GO:0060021 ! roof of mouth development +created_by: dph +creation_date: 2018-02-26T22:55:20Z + +[Term] +id: GO:0062010 +name: primitive palate development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure." [GOC:dph] +is_a: GO:0060021 ! roof of mouth development +created_by: dph +creation_date: 2018-02-26T23:00:48Z + +[Term] +id: GO:0062011 +name: mitochondrial respiratory chain complex IV pre-assembly complex +namespace: cellular_component +def: "A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components." [GOC:lnp, PMID:21068384] +synonym: "COX pre-assemply complex" BROAD [GOC:lnp] +synonym: "COX1 preassemply complex" EXACT [GOC:lnp] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +is_a: GO:0101031 ! chaperone complex +created_by: dph +creation_date: 2018-02-28T14:50:26Z + +[Term] +id: GO:0062012 +name: regulation of small molecule metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw] +synonym: "regulation of small molecule metabolism" EXACT [] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044281 ! small molecule metabolic process +relationship: regulates GO:0044281 ! small molecule metabolic process +created_by: dph +creation_date: 2018-03-19T14:11:54Z + +[Term] +id: GO:0062013 +name: positive regulation of small molecule metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] +synonym: "positive regulation of small molecule metabolism" EXACT [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044281 ! small molecule metabolic process +relationship: positively_regulates GO:0044281 ! small molecule metabolic process +created_by: dph +creation_date: 2018-03-19T14:25:10Z + +[Term] +id: GO:0062014 +name: negative regulation of small molecule metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] +synonym: "negative regulation of small molecule metabolism" EXACT [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044281 ! small molecule metabolic process +relationship: negatively_regulates GO:0044281 ! small molecule metabolic process +created_by: dph +creation_date: 2018-03-19T14:27:23Z + +[Term] +id: GO:0062021 +name: mitotic cohesin dsDNA (leading strand) loading +namespace: biological_process +def: "The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle." [GOC:vw, PMID:29358048] +is_a: GO:0061780 ! mitotic cohesin loading +created_by: dph +creation_date: 2018-04-06T13:04:41Z + +[Term] +id: GO:0062022 +name: mitotic cohesin ssDNA (lagging strand) loading +namespace: biological_process +def: "The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle." [GOC:vw, PMID:29358048] +synonym: "second-DNA capture" EXACT [GOC:vw] +is_a: GO:0061780 ! mitotic cohesin loading +created_by: dph +creation_date: 2018-04-06T13:06:36Z + +[Term] +id: GO:0062023 +name: collagen-containing extracellular matrix +namespace: cellular_component +def: "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." [GOC:BHF, GOC:rph, PMID:21123617] +is_a: GO:0031012 ! extracellular matrix +created_by: dph +creation_date: 2018-04-13T12:47:21Z + +[Term] +id: GO:0062025 +name: regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome." [PMID:28007894] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +relationship: regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +created_by: dph +creation_date: 2018-04-16T13:54:43Z + +[Term] +id: GO:0062026 +name: negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process +namespace: biological_process +def: "Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome." [PMID:28007894] +is_a: GO:0032435 ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:0062025 ! regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +relationship: negatively_regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +created_by: dph +creation_date: 2018-04-16T14:02:20Z + +[Term] +id: GO:0062027 +name: positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process +namespace: biological_process +def: "Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome." [PMID:28007894] +is_a: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:0062025 ! regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +relationship: positively_regulates GO:0031146 ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process +created_by: dph +creation_date: 2018-04-16T14:05:19Z + +[Term] +id: GO:0062028 +name: regulation of stress granule assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule." [PMID:20180778] +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034063 ! stress granule assembly +relationship: regulates GO:0034063 ! stress granule assembly +created_by: dph +creation_date: 2018-04-16T19:12:41Z + +[Term] +id: GO:0062029 +name: positive regulation of stress granule assembly +namespace: biological_process +def: "Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule." [PMID:20180778] +is_a: GO:0062028 ! regulation of stress granule assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034063 ! stress granule assembly +relationship: positively_regulates GO:0034063 ! stress granule assembly +created_by: dph +creation_date: 2018-04-16T19:17:10Z + +[Term] +id: GO:0062030 +name: negative regulation of stress granule assembly +namespace: biological_process +def: "Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule." [PMID:20180778] +is_a: GO:0062028 ! regulation of stress granule assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034063 ! stress granule assembly +relationship: negatively_regulates GO:0034063 ! stress granule assembly +created_by: dph +creation_date: 2018-04-16T19:19:32Z + +[Term] +id: GO:0062031 +name: filamentous growth MAPK cascade +namespace: biological_process +def: "The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth." [PMID:17604854] +is_a: GO:0051403 ! stress-activated MAPK cascade +created_by: dph +creation_date: 2018-04-17T15:18:44Z + +[Term] +id: GO:0062032 +name: cichorine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi." [PMID:24244835] +synonym: "cichorine anabolism" EXACT [] +synonym: "cichorine biosynthesis" EXACT [] +synonym: "cichorine formation" EXACT [] +synonym: "cichorine synthesis" EXACT [] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +created_by: dph +creation_date: 2018-04-19T16:22:09Z + +[Term] +id: GO:0062033 +name: positive regulation of mitotic sister chromatid segregation +namespace: biological_process +def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0045840 ! positive regulation of mitotic nuclear division +is_a: GO:0051984 ! positive regulation of chromosome segregation +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0000070 ! mitotic sister chromatid segregation +relationship: positively_regulates GO:0000070 ! mitotic sister chromatid segregation +created_by: dph +creation_date: 2018-04-23T14:32:23Z + +[Term] +id: GO:0062034 +name: L-pipecolic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine." [PMID:27758894, PMID:28330936] +synonym: "L-pipecolate biosynthetic process" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: dph +creation_date: 2018-04-24T12:19:36Z + +[Term] +id: GO:0062035 +name: sensory perception of cold stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal." [PMID:21335241] +is_a: GO:0050955 ! thermoception +created_by: dph +creation_date: 2018-04-30T13:48:10Z + +[Term] +id: GO:0062036 +name: sensory perception of hot stimulus +namespace: biological_process +def: "The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal." [PMID:21335241] +is_a: GO:0050955 ! thermoception +created_by: dph +creation_date: 2018-04-30T13:50:47Z + +[Term] +id: GO:0062037 +name: D-loop DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind." [PMID:20924116] +synonym: "DNA displacement loop binding" EXACT [] +is_a: GO:0000217 ! DNA secondary structure binding +created_by: dph +creation_date: 2018-04-30T15:21:21Z + +[Term] +id: GO:0062038 +name: positive regulation of pheromone response MAPK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade." [PMID:9315645] +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0090028 ! positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0071507 ! pheromone response MAPK cascade +relationship: positively_regulates GO:0071507 ! pheromone response MAPK cascade +created_by: dph +creation_date: 2018-05-01T13:00:56Z + +[Term] +id: GO:0062039 +name: biofilm matrix +namespace: cellular_component +def: "A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells." [GOC:BHF, PMID:22571672, PMID:27129222, PMID:28516088] +is_a: GO:0031012 ! extracellular matrix +created_by: dph +creation_date: 2018-05-04T12:49:17Z + +[Term] +id: GO:0062040 +name: fungal biofilm matrix +namespace: cellular_component +def: "An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses." [GOC:BHF, PMID:27129222, PMID:28516088] +is_a: GO:0062039 ! biofilm matrix +created_by: dph +creation_date: 2018-05-04T12:54:39Z + +[Term] +id: GO:0062041 +name: positive regulation of meiotic sister chromatid arm separation +namespace: biological_process +def: "Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis." [PMID:20383139] +is_a: GO:0060903 ! positive regulation of meiosis I +is_a: GO:1905134 ! positive regulation of meiotic chromosome separation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0051755 ! meiotic sister chromatid arm separation +relationship: positively_regulates GO:0051755 ! meiotic sister chromatid arm separation +created_by: dph +creation_date: 2018-05-04T18:20:28Z + +[Term] +id: GO:0062042 +name: regulation of cardiac epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:rph, PMID:20951801] +is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +relationship: regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +created_by: dph +creation_date: 2018-05-10T18:09:31Z + +[Term] +id: GO:0062043 +name: positive regulation of cardiac epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:rph, PMID:20951801] +is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition +is_a: GO:0062042 ! regulation of cardiac epithelial to mesenchymal transition +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +relationship: positively_regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +created_by: dph +creation_date: 2018-05-10T18:15:54Z + +[Term] +id: GO:0062044 +name: negative regulation of cardiac epithelial to mesenchymal transition +namespace: biological_process +def: "Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BFH, GOC:rph, PMID:20951801] +is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition +is_a: GO:0062042 ! regulation of cardiac epithelial to mesenchymal transition +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +relationship: negatively_regulates GO:0060317 ! cardiac epithelial to mesenchymal transition +created_by: dph +creation_date: 2018-05-10T18:21:00Z + +[Term] +id: GO:0062045 +name: L-lysine alpha-aminotransferase +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine." [PMID:27758894, PMID:28330936] +is_a: GO:0008483 ! transaminase activity +created_by: dph +creation_date: 2018-05-11T12:13:57Z + +[Term] +id: GO:0062046 +name: dehydropipecolic acid reductase +namespace: molecular_function +def: "Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+." [PMID:27758894, PMID:28330936] +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +created_by: dph +creation_date: 2018-05-11T12:16:00Z + +[Term] +id: GO:0062047 +name: pipecolic acid N-hydroxylase +namespace: molecular_function +def: "Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O." [PMID:27758894, PMID:28330936] +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen +created_by: dph +creation_date: 2018-05-11T12:17:15Z + +[Term] +id: GO:0062048 +name: lymphotoxin complex +namespace: cellular_component +def: "A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations." [PMID:1733951] +synonym: "lymphotoxin alpha-beta" NARROW [] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2018-05-18T18:34:55Z + +[Term] +id: GO:0062049 +name: protein phosphatase inhibitor complex +namespace: cellular_component +def: "A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase." [GOC:bhm, PMID:19407142, PMID:19933100] +xref: ComplexPortal:CPX-1620 +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2018-05-30T19:03:26Z + +[Term] +id: GO:0062050 +name: GPI-mannose ethanolamine phosphate phosphodiesterase activity +namespace: molecular_function +def: "A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor." [PMID:19837036] +is_a: GO:0008081 ! phosphoric diester hydrolase activity +created_by: dph +creation_date: 2018-06-01T18:26:54Z + +[Term] +id: GO:0062051 +name: lipopolysaccharide transport system +namespace: cellular_component +def: "A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner." [PMID:29449493] +is_a: GO:1990351 ! transporter complex +created_by: dph +creation_date: 2018-06-04T18:44:40Z + +[Term] +id: GO:0062052 +name: starch granule initiation +namespace: biological_process +def: "The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts." [PMID:28684429] +is_a: GO:0019252 ! starch biosynthetic process +created_by: dph +creation_date: 2018-06-08T17:18:57Z + +[Term] +id: GO:0062054 +name: fluoride channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [PMID:23991286, PMID:25156118] +is_a: GO:0005253 ! anion channel activity +is_a: GO:1903425 ! fluoride transmembrane transporter activity +created_by: dph +creation_date: 2018-06-25T13:30:23Z + +[Term] +id: GO:0062055 +name: photosynthetic state transition +namespace: biological_process +def: "A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems." [PMID:29967049] +is_a: GO:0042548 ! regulation of photosynthesis, light reaction +created_by: dph +creation_date: 2018-07-16T14:00:57Z + +[Term] +id: GO:0062056 +name: compound eye pigment cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia." [GOC:ha, PMID:8929534] +is_a: GO:0050931 ! pigment cell differentiation +relationship: part_of GO:0001745 ! compound eye morphogenesis +created_by: dph +creation_date: 2018-08-01T12:59:42Z + +[Term] +id: GO:0062057 +name: L-aspartate:fumarate antiporter activity +namespace: molecular_function +def: "Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out)." [PMID:29995997] +is_a: GO:0015138 ! fumarate transmembrane transporter activity +is_a: GO:0015183 ! L-aspartate transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +created_by: dph +creation_date: 2018-08-09T14:25:45Z + +[Term] +id: GO:0062058 +name: transcription factor TFIIH holo complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription factor TFIIH holo complex." [PMID:11259578] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:44:17Z + +[Term] +id: GO:0062059 +name: FACT complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a FACT complex." [PMID:10682845] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:49:30Z + +[Term] +id: GO:0062060 +name: NuA4 histone acetyltransferase complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a NuA4 histone acetyltransferase complex." [PMID:15528408] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:51:45Z + +[Term] +id: GO:0062061 +name: TAP complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a TAP complex." [PMID:17947644] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:54:22Z + +[Term] +id: GO:0062062 +name: oligosaccharyltransferase complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an oligosaccharyltransferase complex." [PMID:12887896] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:56:32Z + +[Term] +id: GO:0062063 +name: BBSome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a BBSome complex." [PMID:20603001] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T13:59:18Z + +[Term] +id: GO:0062064 +name: box C/D snoRNP complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a box C/D snoRNP complex." [PMID:10679015] +is_a: GO:0030519 ! snoRNP binding +created_by: dph +creation_date: 2018-08-31T14:01:03Z + +[Term] +id: GO:0062065 +name: box H/ACA snoRNP complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a box H/ACA snoRNP complex." [PMID:10679015] +is_a: GO:0030519 ! snoRNP binding +created_by: dph +creation_date: 2018-08-31T14:03:43Z + +[Term] +id: GO:0062066 +name: PSII associated light-harvesting complex II binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a PSII associated light-harvesting complex II." [PMID:17400553] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T14:06:01Z + +[Term] +id: GO:0062067 +name: chloroplast photosystem I binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chloroplast photosystem I." [PMID:17400553] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T14:07:46Z + +[Term] +id: GO:0062068 +name: chloroplast photosystem II binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chloroplast photosystem II." [PMID:17400553] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T14:09:17Z + +[Term] +id: GO:0062069 +name: GARP complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a GARP complex." [PMID:20163565] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T14:11:17Z + +[Term] +id: GO:0062070 +name: SAGA complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SAGA complex." [PMID:27185460] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-08-31T14:13:36Z + +[Term] +id: GO:0062071 +name: Pi Mi complex +namespace: cellular_component +def: "A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis." [PMID:30089908] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: dph +creation_date: 2018-09-04T13:40:52Z + +[Term] +id: GO:0062072 +name: H3K9me3 modified histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 9 has been modified by trimethylation." [PMID:30110338] +is_a: GO:0035064 ! methylated histone binding +created_by: dph +creation_date: 2018-09-05T12:58:43Z + +[Term] +id: GO:0062073 +name: histone mRNA stem-loop binding complex +namespace: cellular_component +def: "A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export." [GOC:bhm, PMID:18025107, PMID:23286197] +synonym: "SLBP-MIF4GD complex" NARROW [] +synonym: "SLBP-SLIP1 complex" NARROW [] +xref: ComplexPortal:CPX-1305 +xref: ComplexPortal:CPX-1311 +xref: ComplexPortal:CPX-1312 +xref: ComplexPortal:CPX-1313 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: dph +creation_date: 2018-09-10T13:46:56Z + +[Term] +id: GO:0062074 +name: pollen aperture +namespace: cellular_component +def: "An area where exine is reduced or absent, in the pollen wall." [PMID:30150313] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043667 ! pollen wall +created_by: dph +creation_date: 2018-09-19T19:19:58Z + +[Term] +id: GO:0062075 +name: pollen aperture formation +namespace: biological_process +def: "The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall." [PMID:30150313] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +relationship: part_of GO:0010208 ! pollen wall assembly +created_by: dph +creation_date: 2018-09-19T19:25:59Z + +[Term] +id: GO:0062076 +name: acyl-CoA delta5-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta5-acyl-CoA + acceptor + 2 H2O." [PMID:10601301, PMID:10769175] +synonym: "Acyl-CoA (8-3)-desaturase" EXACT [] +synonym: "acyl-CoA D5-desaturase activity" EXACT [] +synonym: "acyl-CoA delta(5)-desaturase activity" EXACT [] +xref: EC:1.14.19.44 +is_a: GO:0016215 ! acyl-CoA desaturase activity +created_by: dph +creation_date: 2018-09-24T15:33:59Z + +[Term] +id: GO:0062077 +name: phenylacetyl-CoA 1,2-epoxidase complex +namespace: cellular_component +def: "A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)." [GOC:bhm, PMID:21247899] +synonym: "paaABCE complex" NARROW [] +xref: ComplexPortal:CPX-2844 +is_a: GO:1990204 ! oxidoreductase complex +created_by: dph +creation_date: 2018-09-27T12:40:04Z + +[Term] +id: GO:0062078 +name: TSC1-TSC2 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a TSC1-TSC2 complex." [PMID:28561066] +synonym: "tuberin sclerosis complex binding" EXACT [] +synonym: "tuberin-hamartin complex binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2018-10-11T12:31:42Z + +[Term] +id: GO:0062079 +name: ATG2-ATG18 complex +namespace: cellular_component +def: "A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae." [GOC:bhm, PMID:23230146] +xref: ComplexPortal:CPX-361 +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0034045 ! phagophore assembly site membrane +created_by: dph +creation_date: 2018-10-12T13:47:25Z + +[Term] +id: GO:0062080 +name: inhibitory MHC class Ib receptor activity +namespace: molecular_function +def: "Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte." [DOI:10.1002/9780470015902.a0024246] +is_a: GO:0032394 ! MHC class Ib receptor activity +created_by: dph +creation_date: 2018-10-15T15:03:44Z + +[Term] +id: GO:0062081 +name: activating MHC class Ib receptor activity +namespace: molecular_function +def: "Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte." [DOI:10.1002/9780470015902.a0024246] +is_a: GO:0032394 ! MHC class Ib receptor activity +created_by: dph +creation_date: 2018-10-15T15:05:07Z + +[Term] +id: GO:0062082 +name: HLA-E specific inhibitory MHC class Ib receptor activity +namespace: molecular_function +def: "Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte." [DOI:10.1002/9780470015902.a0024246] +is_a: GO:0062080 ! inhibitory MHC class Ib receptor activity +created_by: dph +creation_date: 2018-10-15T15:06:22Z + +[Term] +id: GO:0062083 +name: HLA-G specific inhibitory MHC class Ib receptor activity +namespace: molecular_function +def: "Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte." [DOI:10.1002/9780470015902.a0024246] +is_a: GO:0062080 ! inhibitory MHC class Ib receptor activity +created_by: dph +creation_date: 2018-10-15T15:06:44Z + +[Term] +id: GO:0062084 +name: regulation of capsule polysaccharide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi." [PMID:21917918] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +is_a: GO:1901913 ! regulation of capsule organization +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045227 ! capsule polysaccharide biosynthetic process +relationship: regulates GO:0045227 ! capsule polysaccharide biosynthetic process +created_by: dph +creation_date: 2018-10-31T15:58:08Z + +[Term] +id: GO:0062085 +name: positive regulation of capsule polysaccharide biosynthetic process +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi." [PMID:21917918] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062084 ! regulation of capsule polysaccharide biosynthetic process +is_a: GO:1901915 ! positive regulation of capsule organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045227 ! capsule polysaccharide biosynthetic process +relationship: positively_regulates GO:0045227 ! capsule polysaccharide biosynthetic process +created_by: dph +creation_date: 2018-10-31T16:02:00Z + +[Term] +id: GO:0062086 +name: regulation of vein smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vein smooth muscle contraction." [PMID:8428203] +is_a: GO:0003056 ! regulation of vascular smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014826 ! vein smooth muscle contraction +relationship: regulates GO:0014826 ! vein smooth muscle contraction +created_by: dph +creation_date: 2018-11-02T15:17:26Z + +[Term] +id: GO:0062087 +name: positive regulation of vein smooth muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of vein smooth muscle contraction." [PMID:8428203] +is_a: GO:0062086 ! regulation of vein smooth muscle contraction +is_a: GO:1904695 ! positive regulation of vascular smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014826 ! vein smooth muscle contraction +relationship: positively_regulates GO:0014826 ! vein smooth muscle contraction +created_by: dph +creation_date: 2018-11-02T15:20:47Z + +[Term] +id: GO:0062088 +name: negative regulation of vein smooth muscle contraction +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of vein smooth muscle contraction." [PMID:8428203] +is_a: GO:0062086 ! regulation of vein smooth muscle contraction +is_a: GO:1904694 ! negative regulation of vascular smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014826 ! vein smooth muscle contraction +relationship: negatively_regulates GO:0014826 ! vein smooth muscle contraction +created_by: dph +creation_date: 2018-11-02T15:28:32Z + +[Term] +id: GO:0062089 +name: regulation of taurine biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of taurine biosynthesis." [GOC:BHF, PMID:18648510, PMID:24911144] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042412 ! taurine biosynthetic process +relationship: regulates GO:0042412 ! taurine biosynthetic process +created_by: dph +creation_date: 2018-11-07T14:05:44Z + +[Term] +id: GO:0062090 +name: positive regulation of taurine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of taurine biosynthesis." [GOC:BHF, PMID:18648510, PMID:24911144] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:0062089 ! regulation of taurine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042412 ! taurine biosynthetic process +relationship: positively_regulates GO:0042412 ! taurine biosynthetic process +created_by: dph +creation_date: 2018-11-07T14:10:58Z + +[Term] +id: GO:0062091 +name: Ycf2/FtsHi complex +namespace: cellular_component +def: "A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma." [PMID:30309901] +synonym: "TIC complex associated chloroplast protein import motor" EXACT [] +is_a: GO:1904949 ! ATPase complex +created_by: dph +creation_date: 2018-11-08T20:06:11Z + +[Term] +id: GO:0062092 +name: Yae1-Lto1 complex +namespace: cellular_component +def: "A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p." [PMID:26182403] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: dph +creation_date: 2018-11-15T17:39:46Z + +[Term] +id: GO:0062093 +name: lysophagy +namespace: biological_process +def: "The selective autophagy process in which a damaged lysosome is degraded by macroautophagy." [PMID:28743755] +is_a: GO:0061912 ! selective autophagy +created_by: dph +creation_date: 2018-11-20T16:47:11Z + +[Term] +id: GO:0062094 +name: stomach development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0048565 ! digestive tract development +created_by: dph +creation_date: 2018-11-20T18:15:45Z + +[Term] +id: GO:0062095 +name: endoplasmic reticulum-peroxisome tethering +namespace: biological_process +def: "The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:28463579] +is_a: GO:0060151 ! peroxisome localization +is_a: GO:0140056 ! organelle localization by membrane tethering +created_by: dph +creation_date: 2018-11-21T13:28:50Z + +[Term] +id: GO:0062096 +name: kinetochore disassembly +namespace: biological_process +def: "The disaggregation of a kinetochore into its constituent components." [GOC:mah, PMID:27611693] +is_a: GO:0051383 ! kinetochore organization +is_a: GO:1903008 ! organelle disassembly +created_by: dph +creation_date: 2018-11-26T16:34:55Z + +[Term] +id: GO:0062097 +name: chemosynthesis +namespace: biological_process +def: "The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane." [PMID:25050523] +xref: Wikipedia:Chemosynthesis +is_a: GO:0044237 ! cellular metabolic process +created_by: dph +creation_date: 2018-11-29T13:18:55Z + +[Term] +id: GO:0062098 +name: regulation of programmed necrotic cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of programmed necrotic cell death." [GOC:aruk, GOC:rph, PMID:27258785] +is_a: GO:0010939 ! regulation of necrotic cell death +is_a: GO:0043067 ! regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097300 ! programmed necrotic cell death +relationship: regulates GO:0097300 ! programmed necrotic cell death +created_by: dph +creation_date: 2018-11-29T14:58:26Z + +[Term] +id: GO:0062099 +name: negative regulation of programmed necrotic cell death +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of programmed necrotic cell death." [GOC:aruk, GOC:rph, PMID:27258785] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0060547 ! negative regulation of necrotic cell death +is_a: GO:0062098 ! regulation of programmed necrotic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097300 ! programmed necrotic cell death +relationship: negatively_regulates GO:0097300 ! programmed necrotic cell death +created_by: dph +creation_date: 2018-11-29T15:05:56Z + +[Term] +id: GO:0062100 +name: positive regulation of programmed necrotic cell death +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of programmed necrotic cell death." [GOC:aruk, GOC:rph, PMID:27258785] +is_a: GO:0010940 ! positive regulation of necrotic cell death +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:0062098 ! regulation of programmed necrotic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097300 ! programmed necrotic cell death +relationship: positively_regulates GO:0097300 ! programmed necrotic cell death +created_by: dph +creation_date: 2018-11-29T15:08:35Z + +[Term] +id: GO:0062101 +name: peptidyl-aspartic acid 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2." [PMID:1378441, PMID:1856229] +xref: EC:1.14.11.16 +xref: MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN +xref: RHEA:11508 +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: dph +creation_date: 2018-12-06T14:01:15Z + +[Term] +id: GO:0062102 +name: female germline stem cell symmetric division +namespace: biological_process +def: "Division of a female germline stem cell to produce two germline stem cells of the same type as the parent." [GOC:ha, PMID:30248087] +is_a: GO:0098729 ! germline stem cell symmetric division +created_by: dph +creation_date: 2018-12-18T14:17:54Z + +[Term] +id: GO:0062103 +name: double-stranded RNA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of double-stranded RNA." [PMID:19701182] +synonym: "double-stranded RNA biosynthesis" EXACT [] +synonym: "dsRNA biosynthesis" EXACT [] +synonym: "dsRNA biosynthetic process" EXACT [GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:rl] +is_a: GO:0032774 ! RNA biosynthetic process +created_by: dph +creation_date: 2019-01-07T13:29:47Z + +[Term] +id: GO:0062104 +name: pumilio-response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA." [PMID:30601114] +synonym: "PRE binding" EXACT [PMID:30601114] +is_a: GO:0003723 ! RNA binding +created_by: dph +creation_date: 2019-01-11T13:38:26Z + +[Term] +id: GO:0062105 +name: RNA 2'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide." [PMID:30626973, RHEA:58956] +xref: RHEA:58956 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008173 ! RNA methyltransferase activity +created_by: dph +creation_date: 2019-01-23T14:23:00Z + +[Term] +id: GO:0062107 +name: regulation of protein localization to non-growing cell tip +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip." [PMID:18328707] +is_a: GO:1903066 ! regulation of protein localization to cell tip +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902487 ! protein localization to non-growing cell tip +relationship: regulates GO:1902487 ! protein localization to non-growing cell tip +created_by: dph +creation_date: 2019-02-05T12:59:18Z + +[Term] +id: GO:0062108 +name: negative regulation of protein localization to non-growing cell tip +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip." [PMID:18328707] +is_a: GO:0062107 ! regulation of protein localization to non-growing cell tip +is_a: GO:1903067 ! negative regulation of protein localization to cell tip +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902487 ! protein localization to non-growing cell tip +relationship: negatively_regulates GO:1902487 ! protein localization to non-growing cell tip +created_by: dph +creation_date: 2019-02-05T13:03:52Z + +[Term] +id: GO:0062109 +name: regulation of DNA recombinase disassembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components." [PMID:30297419] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990986 ! DNA recombinase disassembly +relationship: regulates GO:1990986 ! DNA recombinase disassembly +created_by: dph +creation_date: 2019-02-05T13:53:19Z + +[Term] +id: GO:0062110 +name: negative regulation of DNA recombinase disassembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components." [PMID:30297419] +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +is_a: GO:0062109 ! regulation of DNA recombinase disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990986 ! DNA recombinase disassembly +relationship: negatively_regulates GO:1990986 ! DNA recombinase disassembly +created_by: dph +creation_date: 2019-02-05T13:57:35Z + +[Term] +id: GO:0062111 +name: zinc ion import into organelle +namespace: biological_process +def: "The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle." [PMID:29529046] +is_a: GO:0071577 ! zinc ion transmembrane transport +created_by: dph +creation_date: 2019-02-05T15:27:38Z + +[Term] +id: GO:0062112 +name: fatty acid primary amide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a fatty acid primary amide." [PMID:10079066, PMID:15952893] +synonym: "FAPA biosynthesis" EXACT [] +synonym: "FAPA biosynthetic process" EXACT [] +synonym: "fatty acid amide biosynthesis" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0062126 ! fatty acid primary amide metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901570 ! fatty acid derivative biosynthetic process +created_by: dph +creation_date: 2019-02-20T12:49:43Z + +[Term] +id: GO:0062113 +name: early phagosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an eary phagosome." [PMID:18813294] +synonym: "early phagocytic vesicle lumen" EXACT [] +is_a: GO:0097013 ! phagocytic vesicle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0032009 ! early phagosome +relationship: part_of GO:0032009 ! early phagosome +created_by: dph +creation_date: 2019-02-22T12:58:47Z + +[Term] +id: GO:0062116 +name: phenyloplast +namespace: cellular_component +def: "A chloroplast-derived plastid in which the solid form of phenol is stored." [PMID:24683183] +is_a: GO:0009536 ! plastid +created_by: dph +creation_date: 2019-03-15T11:57:05Z + +[Term] +id: GO:0062119 +name: LinE complex +namespace: cellular_component +def: "A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins." [PMID:30640914] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: dph +creation_date: 2019-03-19T14:00:26Z + +[Term] +id: GO:0062120 +name: LinE complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins." [PMID:30640914] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0030999 ! linear element assembly +created_by: dph +creation_date: 2019-03-19T14:14:25Z + +[Term] +id: GO:0062121 +name: linear element maturation +namespace: biological_process +def: "The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements." [PMID:30640914] +synonym: "LinE chromosome loading" EXACT [GOC:mah] +synonym: "LinE focus formation" EXACT [GOC:mah] +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +relationship: part_of GO:0030999 ! linear element assembly +created_by: dph +creation_date: 2019-03-19T14:19:27Z + +[Term] +id: GO:0062122 +name: histone methyltransferase activity (H3-K37 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein." [PMID:30773398] +synonym: "histone lysine N-methyltransferase activity (H3-K37 specific)" EXACT [] +is_a: GO:0018024 ! histone-lysine N-methyltransferase activity +created_by: dph +creation_date: 2019-04-01T13:30:11Z + +[Term] +id: GO:0062123 +name: regulation of linear element maturation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of linear element maturation." [PMID:30640914] +is_a: GO:0090006 ! regulation of linear element assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0062121 ! linear element maturation +relationship: regulates GO:0062121 ! linear element maturation +created_by: dph +creation_date: 2019-04-23T13:36:20Z + +[Term] +id: GO:0062124 +name: 4-hydroxybutyrate receptor activity +namespace: molecular_function +def: "Combining with 4-hydroxybutyrte to initiate a change in cell activity." [PMID:17197387] +synonym: "gamma-hydroxybutyrate receptor activity" EXACT [PMID:17197387] +is_a: GO:0038023 ! signaling receptor activity +created_by: dph +creation_date: 2019-05-15T12:22:38Z + +[Term] +id: GO:0062125 +name: regulation of mitochondrial gene expression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA)." [PMID:28285835] +is_a: GO:0010468 ! regulation of gene expression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0140053 ! mitochondrial gene expression +relationship: regulates GO:0140053 ! mitochondrial gene expression +created_by: dph +creation_date: 2019-05-30T16:45:04Z + +[Term] +id: GO:0062126 +name: fatty acid primary amide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides." [PMID:11128635] +synonym: "primary fatty amide metabolic process" EXACT [] +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901568 ! fatty acid derivative metabolic process +created_by: dph +creation_date: 2019-05-30T18:23:02Z + +[Term] +id: GO:0062127 +name: fatty acid primary amide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of primary fatty amides." [PMID:11128635] +synonym: "primary fatty amide catabolic process" EXACT [] +is_a: GO:0016042 ! lipid catabolic process +is_a: GO:0062126 ! fatty acid primary amide metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901569 ! fatty acid derivative catabolic process +created_by: dph +creation_date: 2019-05-30T18:26:49Z + +[Term] +id: GO:0062128 +name: MutSgamma complex +namespace: cellular_component +def: "A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5." [PMID:27648641, PMID:7622037, PMID:8001134, PMID:9374523] +synonym: "Msh4-Msh5 complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: dph +creation_date: 2019-06-04T14:48:15Z + +[Term] +id: GO:0062129 +name: chitin-based extracellular matrix +namespace: cellular_component +def: "Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet." [PMID:23955854] +synonym: "chitin-based ECM" EXACT [GOC:dph] +is_a: GO:0031012 ! extracellular matrix +created_by: dph +creation_date: 2019-06-13T12:57:13Z + +[Term] +id: GO:0062130 +name: adhesive extracellular matrix +namespace: cellular_component +def: "A extracellular matrix which attaches an organism to a substrate." [GOC:dph, GOC:ha, PMID:825230] +synonym: "puparial glue" NARROW [GOC:ha] +is_a: GO:0031012 ! extracellular matrix +created_by: dph +creation_date: 2019-06-21T12:35:06Z + +[Term] +id: GO:0062131 +name: 3-butenylglucosinolate 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O." [PMID:18945935] +synonym: "But-3-enyl Glucosinolate-2-hydroxylase activity" EXACT [] +xref: MetaCyc:RXNQT-4343 +xref: RHEA:60628 +is_a: GO:0051213 ! dioxygenase activity +created_by: dph +creation_date: 2019-06-24T16:45:18Z + +[Term] +id: GO:0062132 +name: regulation of L-glutamine biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis." [GOC:ha, PMID:19755423] +is_a: GO:0000820 ! regulation of glutamine family amino acid metabolic process +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901704 ! L-glutamine biosynthetic process +relationship: regulates GO:1901704 ! L-glutamine biosynthetic process +created_by: dph +creation_date: 2019-06-27T13:44:21Z + +[Term] +id: GO:0062133 +name: negative regulation of L-glutamine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis." [GOC:ha, PMID:19755423] +is_a: GO:0062132 ! regulation of L-glutamine biosynthetic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901704 ! L-glutamine biosynthetic process +relationship: negatively_regulates GO:1901704 ! L-glutamine biosynthetic process +created_by: dph +creation_date: 2019-06-27T13:47:21Z + +[Term] +id: GO:0062134 +name: positive regulation of L-glutamine biosynthetic process +namespace: biological_process +def: "Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis." [GOC:ha, PMID:19755423] +is_a: GO:0062132 ! regulation of L-glutamine biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901704 ! L-glutamine biosynthetic process +relationship: positively_regulates GO:1901704 ! L-glutamine biosynthetic process +created_by: dph +creation_date: 2019-06-27T13:49:29Z + +[Term] +id: GO:0062136 +name: low-density lipoprotein receptor complex +namespace: cellular_component +def: "A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors." [GOC:bhm, PMID:26005850] +synonym: "LDL receptor complex" EXACT [GOC:dph] +synonym: "LDLR complex" EXACT [GOC:dph] +synonym: "low-density lipoprotein particle receptor complex" EXACT [GOC:dph] +is_a: GO:0062137 ! cargo receptor complex +is_a: GO:0098797 ! plasma membrane protein complex +created_by: dph +creation_date: 2019-07-02T13:41:28Z + +[Term] +id: GO:0062137 +name: cargo receptor complex +namespace: cellular_component +def: "Any protein complex that is part of a membrane and which functions as a cargo receptor." [PMID:27903609] +is_a: GO:0098796 ! membrane protein complex +created_by: dph +creation_date: 2019-07-08T18:09:01Z + +[Term] +id: GO:0062139 +name: camera-type eye photoreceptor cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure." [PMID:20648062, PMID:30237290] +is_a: GO:0042462 ! eye photoreceptor cell development +relationship: part_of GO:0043010 ! camera-type eye development +created_by: dph +creation_date: 2019-08-06T12:40:36Z + +[Term] +id: GO:0062140 +name: hyphae septin collar +namespace: cellular_component +def: "A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell." [PMID:29567712] +synonym: "septin collar of invasive hyphae" RELATED [] +is_a: GO:0032173 ! septin collar +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +created_by: dph +creation_date: 2019-08-06T14:31:04Z + +[Term] +id: GO:0062141 +name: nuclear exosome targeting complex +namespace: cellular_component +def: "A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts." [PMID:21855801, PMID:29844170] +synonym: "NEXT complex" EXACT [PMID:21855801, PMID:29844170] +is_a: GO:0032991 ! protein-containing complex +created_by: dph +creation_date: 2019-08-29T14:46:59Z + +[Term] +id: GO:0062142 +name: L-beta-ethynylserine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria." [PMID:3082841, PMID:30867596] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0043453 ! alkyne biosynthetic process +created_by: dph +creation_date: 2019-09-02T16:39:59Z + +[Term] +id: GO:0062143 +name: L-propargylglycine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria." [PMID:30867596] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0043453 ! alkyne biosynthetic process +created_by: dph +creation_date: 2019-09-02T16:45:12Z + +[Term] +id: GO:0062144 +name: L-propargylglycine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H(+) + L-propargylglycine." [PMID:30867596, RHEA:59892] +xref: RHEA:59892 +is_a: GO:0016848 ! carbon-halide lyase activity +created_by: dph +creation_date: 2019-09-02T16:48:52Z + +[Term] +id: GO:0062145 +name: L-propargylglycine--L-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate." [PMID:30867596, RHEA:59896] +xref: RHEA:59896 +is_a: GO:0016881 ! acid-amino acid ligase activity +created_by: dph +creation_date: 2019-09-02T16:56:59Z + +[Term] +id: GO:0062146 +name: 4-chloro-allylglycine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+)." [PMID:30867596, RHEA:59888] +xref: RHEA:59888 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2019-09-02T16:59:30Z + +[Term] +id: GO:0062147 +name: L-lysine 4-chlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate." [PMID:30867596, RHEA:59884] +xref: RHEA:59884 +is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated +created_by: dph +creation_date: 2019-09-02T17:01:46Z + +[Term] +id: GO:0062148 +name: L-gamma-glutamyl-L-propargylglycine hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate." [PMID:30867596, RHEA:59900] +xref: RHEA:59900 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +created_by: dph +creation_date: 2019-09-02T17:04:43Z + +[Term] +id: GO:0062149 +name: detection of stimulus involved in sensory perception of pain +namespace: biological_process +def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031] +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0019233 ! sensory perception of pain +relationship: part_of GO:0019233 ! sensory perception of pain +created_by: dph +creation_date: 2019-09-13T13:48:47Z + +[Term] +id: GO:0062150 +name: amorpha-4,11-diene 12-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]." [PMID:16458889, PMID:16612385, PMID:23246612, RHEA:32999] +xref: EC:1.14.14.114 +xref: RHEA:32999 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dph +creation_date: 2019-09-13T14:48:12Z + +[Term] +id: GO:0062151 +name: catalase complex +namespace: cellular_component +def: "A protein-containing complex that is capable of catalase activity." [GOC:bhm, PMID:10656833] +is_a: GO:1990204 ! oxidoreductase complex +created_by: dph +creation_date: 2019-09-17T12:18:02Z + +[Term] +id: GO:0062152 +name: mRNA (cytidine-5-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine." [PMID:22395603, PMID:23871666, RHEA:61464] +synonym: "mRNA (cytosine-5-)-methyltransferase activity" EXACT [] +xref: RHEA:61464 +is_a: GO:0008174 ! mRNA methyltransferase activity +created_by: dph +creation_date: 2019-09-18T14:40:32Z + +[Term] +id: GO:0062153 +name: C5-methylcytidine-containing RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA molecule modified by C5-methylcytidine." [PMID:28418038] +synonym: "C5-methylcytosine-containing RNA binding" EXACT [] +is_a: GO:0003723 ! RNA binding +created_by: dph +creation_date: 2019-09-18T14:46:22Z + +[Term] +id: GO:0062154 +name: N6-mAMP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H(+) + H2O + N6-methyl-AMP = IMP + methylamine." [PMID:29884623, RHEA:16001] +synonym: "MAPDA" EXACT [PMID:29884623] +xref: RHEA:16001 +is_a: GO:0019239 ! deaminase activity +created_by: dph +creation_date: 2019-09-20T13:16:37Z + +[Term] +id: GO:0062155 +name: curli secretion complex +namespace: cellular_component +def: "A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms." [PMID:25219853] +is_a: GO:1902495 ! transmembrane transporter complex +relationship: part_of GO:0009279 ! cell outer membrane +created_by: dph +creation_date: 2019-09-20T14:05:13Z + +[Term] +id: GO:0062156 +name: mitochondrial ATP-gated potassium channel activity +namespace: molecular_function +def: "Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane." [PMID:31435016] +synonym: "mitochondrial potassium channel activity" EXACT [] +synonym: "mitoK-ATP activity" EXACT [] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0035381 ! ATP-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity +created_by: dph +creation_date: 2019-09-20T16:07:07Z + +[Term] +id: GO:0062157 +name: mitochondrial ATP-gated potassium channel complex +namespace: cellular_component +def: "A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane." [PMID:31435016] +is_a: GO:0034705 ! potassium channel complex +created_by: dph +creation_date: 2019-09-20T16:17:05Z + +[Term] +id: GO:0062158 +name: chloride:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out)." [PMID:14985752] +is_a: GO:0015108 ! chloride transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity +created_by: dph +creation_date: 2019-09-24T19:26:32Z + +[Term] +id: GO:0062159 +name: contractile vacuole complex +namespace: cellular_component +def: "A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory." [PMID:23890380] +synonym: "CVC" RELATED [PMID:23890380] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +created_by: dph +creation_date: 2019-09-26T14:20:14Z + +[Term] +id: GO:0062160 +name: spongiome +namespace: cellular_component +def: "A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory." [PMID:23890380] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0062159 ! contractile vacuole complex +created_by: dph +creation_date: 2019-09-26T14:30:41Z + +[Term] +id: GO:0062161 +name: regulation of pyocyanine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process." [PMID:28715477] +synonym: "regulation of pyocyanin biosynthetic process" EXACT [] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0106220 ! pyocyanine biosynthetic process +relationship: regulates GO:0106220 ! pyocyanine biosynthetic process +created_by: dph +creation_date: 2019-11-06T14:36:27Z + +[Term] +id: GO:0062162 +name: positive regulation of pyocyanine biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process." [PMID:28715477] +synonym: "positive regulation of pyocyanin biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0062161 ! regulation of pyocyanine biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0106220 ! pyocyanine biosynthetic process +relationship: positively_regulates GO:0106220 ! pyocyanine biosynthetic process +created_by: dph +creation_date: 2019-11-06T14:40:35Z + +[Term] +id: GO:0062163 +name: pseudohyphal septin ring assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection." [PMID:29567712] +is_a: GO:0000921 ! septin ring assembly +created_by: dph +creation_date: 2019-11-07T15:46:26Z + +[Term] +id: GO:0062164 +name: regulation of pseudohyphal septin ring assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly." [PMID:29567712] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0051493 ! regulation of cytoskeleton organization +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0062163 ! pseudohyphal septin ring assembly +relationship: regulates GO:0062163 ! pseudohyphal septin ring assembly +created_by: dph +creation_date: 2019-11-07T15:52:20Z + +[Term] +id: GO:0062165 +name: positive regulation of pseudohyphal septin ring assembly +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation." [PMID:29567712] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0062164 ! regulation of pseudohyphal septin ring assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0062163 ! pseudohyphal septin ring assembly +relationship: positively_regulates GO:0062163 ! pseudohyphal septin ring assembly +created_by: dph +creation_date: 2019-11-07T15:55:38Z + +[Term] +id: GO:0062166 +name: negative regulation of pseudohyphal septin ring assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly." [PMID:29567712] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:0062164 ! regulation of pseudohyphal septin ring assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0062163 ! pseudohyphal septin ring assembly +relationship: negatively_regulates GO:0062163 ! pseudohyphal septin ring assembly +created_by: dph +creation_date: 2019-11-07T15:57:39Z + +[Term] +id: GO:0062167 +name: complement component C1q complex +namespace: cellular_component +def: "A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning." [PMID:29449492] +synonym: "C1q" EXACT [] +synonym: "Complement 1q" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: dph +creation_date: 2019-11-12T13:21:57Z + +[Term] +id: GO:0062168 +name: negative regulation of plus-end directed microtubule sliding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding." [PMID:21892183] +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0062169 ! regulation of plus-end directed microtubule sliding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031535 ! plus-end directed microtubule sliding +relationship: negatively_regulates GO:0031535 ! plus-end directed microtubule sliding +created_by: dph +creation_date: 2019-11-12T17:56:47Z + +[Term] +id: GO:0062169 +name: regulation of plus-end directed microtubule sliding +namespace: biological_process +def: "Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding." [PMID:21892183] +is_a: GO:0060632 ! regulation of microtubule-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031535 ! plus-end directed microtubule sliding +relationship: regulates GO:0031535 ! plus-end directed microtubule sliding +created_by: dph +creation_date: 2019-11-12T18:01:32Z + +[Term] +id: GO:0062170 +name: lutein metabolic process +namespace: biological_process +def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein." [PMID:24397433] +synonym: "lutein metabolism" EXACT [] +is_a: GO:0016122 ! xanthophyll metabolic process +created_by: dph +creation_date: 2019-11-18T15:56:36Z + +[Term] +id: GO:0062171 +name: lutein biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lutein." [PMID:24397433] +synonym: "lutein anabolism" EXACT [] +synonym: "lutein biosynthesis" EXACT [] +synonym: "lutein formation" EXACT [] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:0062170 ! lutein metabolic process +created_by: dph +creation_date: 2019-11-18T16:01:00Z + +[Term] +id: GO:0062172 +name: lutein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lutein." [PMID:24397433] +synonym: "lutein breakdown" EXACT [] +synonym: "lutein catabolism" EXACT [] +synonym: "lutein degradation" EXACT [] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:0062170 ! lutein metabolic process +created_by: dph +creation_date: 2019-11-18T16:06:07Z + +[Term] +id: GO:0062173 +name: brexanolone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways by which living organisms transform brexanolone." [PMID:24390875] +synonym: "allopregnanolone metabolic process" EXACT [] +synonym: "allopregnanolone metabolism" EXACT [] +synonym: "allotetrahydroprogesterone metabolic process" EXACT [] +synonym: "allotetrahydroprogesterone metabolism" EXACT [] +synonym: "brexanolone metabolism" EXACT [] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: dph +creation_date: 2019-11-18T19:42:45Z + +[Term] +id: GO:0062174 +name: brexanolone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of brexanolone." [PMID:24390875] +synonym: "allopregnanolone anabolism" EXACT [] +synonym: "allopregnanolone biosynthesis" EXACT [] +synonym: "allopregnanolone biosynthetic process" EXACT [] +synonym: "allopregnanolone synthesis" EXACT [] +synonym: "allotetrahydroprogesterone anabolism" EXACT [] +synonym: "allotetrahydroprogesterone biosynthesis" EXACT [] +synonym: "allotetrahydroprogesterone biosynthetic process" EXACT [] +synonym: "allotetrahydroprogesterone synthesis" EXACT [] +synonym: "brexanolone anabolism" EXACT [] +synonym: "brexanolone biosynthesis" EXACT [] +synonym: "brexanolone synthesis" EXACT [] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0062173 ! brexanolone metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +created_by: dph +creation_date: 2019-11-18T19:48:14Z + +[Term] +id: GO:0062175 +name: brexanolone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of brexanolone." [PMID:24390875] +synonym: "allopregnanolone breakdown" EXACT [] +synonym: "allopregnanolone catabolic process" EXACT [] +synonym: "allopregnanolone catabolism" EXACT [] +synonym: "allopregnanolone degradation" EXACT [] +synonym: "allotetrahydroprogesterone breakdown" EXACT [] +synonym: "allotetrahydroprogesterone catabolic process" EXACT [] +synonym: "allotetrahydroprogesterone catabolism" EXACT [] +synonym: "allotetrahydroprogesterone degradation" EXACT [] +synonym: "brexanolone breakdown" EXACT [] +synonym: "brexanolone catabolism" EXACT [] +synonym: "brexanolone degradation" EXACT [] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0062173 ! brexanolone metabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +created_by: dph +creation_date: 2019-11-18T19:57:46Z + +[Term] +id: GO:0062176 +name: R-loop disassembly +namespace: biological_process +def: "A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability." [PMID:28790157] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006261 ! DNA-dependent DNA replication +created_by: dph +creation_date: 2019-11-19T12:47:04Z + +[Term] +id: GO:0062177 +name: radial spoke assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules." [PMID:21613541, PMID:21692193, PMID:24124175, PMID:27940518, PMID:8408197] +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0035082 ! axoneme assembly +created_by: dph +creation_date: 2019-11-20T17:50:08Z + +[Term] +id: GO:0062179 +name: vitamin D 23-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of C-23 of any form of vitamin D." [PMID:22100522, PMID:30205156] +is_a: GO:0004497 ! monooxygenase activity +created_by: dph +creation_date: 2019-11-26T17:10:29Z + +[Term] +id: GO:0062180 +name: 25-hydroxycholecalciferol-23-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]." [PMID:22100522, PMID:30205156, RHEA:46616] +xref: RHEA:46616 +is_a: GO:0062179 ! vitamin D 23-hydroxylase activity +created_by: dph +creation_date: 2019-11-26T17:12:22Z + +[Term] +id: GO:0062181 +name: 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity +namespace: molecular_function +def: "Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]." [PMID:22100522, PMID:30205156, RHEA:49192] +xref: RHEA:49192 +is_a: GO:0062179 ! vitamin D 23-hydroxylase activity +created_by: dph +creation_date: 2019-11-26T17:16:39Z + +[Term] +id: GO:0062182 +name: all-trans retinoic acid 4-hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:9250660, PMID:9716180, RHEA:51492] +xref: RHEA:51492 +is_a: GO:0008401 ! retinoic acid 4-hydroxylase activity +created_by: dph +creation_date: 2019-11-26T18:36:06Z + +[Term] +id: GO:0062183 +name: all-trans retinoic acid 18-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:22020119, RHEA:55856] +xref: RHEA:55856 +is_a: GO:0004497 ! monooxygenase activity +created_by: dph +creation_date: 2019-11-26T18:41:32Z + +[Term] +id: GO:0062184 +name: testosterone 16-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:46304] +xref: RHEA:46304 +is_a: GO:0004497 ! monooxygenase activity +created_by: dph +creation_date: 2019-11-26T18:43:43Z + +[Term] +id: GO:0062185 +name: secalciferol 1-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]." [PMID:10518789, RHEA:49064] +xref: RHEA:49064 +is_a: GO:0004497 ! monooxygenase activity +created_by: dph +creation_date: 2019-11-26T18:46:18Z + +[Term] +id: GO:0062186 +name: anandamide epoxidase activity +namespace: molecular_function +def: "Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide." [PMID:21289075] +synonym: "arachidonoylethanolamide epoxidase activity" EXACT [PMID:21289075] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: dph +creation_date: 2019-11-26T18:49:50Z + +[Term] +id: GO:0062187 +name: anandamide 8,9 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53140] +xref: RHEA:53140 +is_a: GO:0062186 ! anandamide epoxidase activity +created_by: dph +creation_date: 2019-11-26T18:51:34Z + +[Term] +id: GO:0062188 +name: anandamide 11,12 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53144] +xref: RHEA:53144 +is_a: GO:0062186 ! anandamide epoxidase activity +created_by: dph +creation_date: 2019-11-26T18:53:52Z + +[Term] +id: GO:0062189 +name: anandamide 14,15 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]." [PMID:21289075, RHEA:53148] +xref: RHEA:53148 +is_a: GO:0062186 ! anandamide epoxidase activity +created_by: dph +creation_date: 2019-11-26T18:57:55Z + +[Term] +id: GO:0062191 +name: galactoxylomannan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals." [PMID:16441437, PMID:18952901, PMID:19684080, PMID:21843086] +synonym: "galactoxylomannan anabolism" EXACT [] +synonym: "galactoxylomannan biosynthesis" EXACT [] +synonym: "galactoxylomannan formation" EXACT [] +synonym: "galactoxylomannan synthesis" EXACT [] +synonym: "GalXM biosynthetic process" EXACT [] +synonym: "glucuronoxylomannogalactan biosynthetic process" EXACT [] +is_a: GO:0051278 ! fungal-type cell wall polysaccharide biosynthetic process +created_by: dph +creation_date: 2019-12-06T14:44:36Z + +[Term] +id: GO:0062192 +name: L-rhamnose mutarotase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose." [RHEA:25584] +xref: EC:5.1.3.32 +xref: RHEA:25584 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives +created_by: dph +creation_date: 2019-12-09T16:45:45Z + +[Term] +id: GO:0062193 +name: D-ribose pyranase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose." [RHEA:25432] +xref: EC:5.4.99.62 +xref: RHEA:25432 +is_a: GO:0016866 ! intramolecular transferase activity +created_by: dph +creation_date: 2019-12-09T16:49:07Z + +[Term] +id: GO:0062194 +name: cytoplasmic microtubule minus-end +namespace: cellular_component +def: "A microtubule minus end that is part of a cytoplasmic microtubule." [PMID:18061564] +is_a: GO:0036449 ! microtubule minus-end +intersection_of: GO:0036449 ! microtubule minus-end +intersection_of: part_of GO:0005881 ! cytoplasmic microtubule +relationship: part_of GO:0005881 ! cytoplasmic microtubule +created_by: dph +creation_date: 2019-12-09T19:06:36Z + +[Term] +id: GO:0062195 +name: microtubule bundle maintenance +namespace: biological_process +def: "The organization process that preserves a microtubule bundle in a stable functional or structural state." [PMID:18061564] +is_a: GO:0043954 ! cellular component maintenance +created_by: dph +creation_date: 2019-12-09T19:10:30Z + +[Term] +id: GO:0062196 +name: regulation of lysosome size +namespace: biological_process +def: "Any process that modulates the size of a lysosome." [PMID:31314175] +is_a: GO:0032535 ! regulation of cellular component size +created_by: dph +creation_date: 2019-12-09T21:06:44Z + +[Term] +id: GO:0062197 +name: cellular response to chemical stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." [PMID:26653712] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: dph +creation_date: 2019-12-10T14:42:03Z + +[Term] +id: GO:0062198 +name: obsolete rDNA replication pause site heterochromatin +namespace: cellular_component +def: "OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause." [PMID:25417108] +comment: This term was obsoleted because it does not represent a specific cellular component. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19178 xsd:anyURI +is_obsolete: true +created_by: dph +creation_date: 2019-12-11T20:32:24Z + +[Term] +id: GO:0062199 +name: chromosome, centromeric inner repeat region +namespace: cellular_component +def: "The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm." [PMID:21437270] +synonym: "chromosome, centric outer repeat region" RELATED [] +is_a: GO:0098687 ! chromosomal region +relationship: part_of GO:0000775 ! chromosome, centromeric region +created_by: dph +creation_date: 2019-12-11T20:38:14Z + +[Term] +id: GO:0062200 +name: RAM/MOR signaling pathway +namespace: biological_process +def: "An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase." [PMID:15731009, PMID:16096637, PMID:20805322, PMID:20826805, PMID:21246752, PMID:22629372] +synonym: "MOR signaling pathway" NARROW [] +synonym: "morphogenesis Orb6 network" EXACT [] +synonym: "RAM signaling pathway" NARROW [] +is_a: GO:0035556 ! intracellular signal transduction +created_by: dph +creation_date: 2019-12-17T20:21:12Z + +[Term] +id: GO:0062201 +name: actin wave +namespace: cellular_component +def: "A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis." [PMID:26190109, PMID:31230946, PMID:31390543, PMID:31678045, PMID:31774725] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005884 ! actin filament +relationship: part_of GO:0015629 ! actin cytoskeleton +created_by: dph +creation_date: 2020-01-02T13:45:03Z + +[Term] +id: GO:0062202 +name: Labd-13(16),14-diene-9-ol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol." [PMID:29315936, RHEA:62184] +xref: RHEA:62184 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: dph +creation_date: 2020-01-02T15:46:00Z + +[Term] +id: GO:0062203 +name: Viteagnusin D synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D." [PMID:29315936, RHEA:62180] +xref: RHEA:62180 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: dph +creation_date: 2020-01-02T18:25:47Z + +[Term] +id: GO:0062204 +name: (13S)-vitexifolin A synthase activity +namespace: molecular_function +def: "Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate." [PMID:29315936, RHEA:40027] +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: dph +creation_date: 2020-01-03T13:24:50Z + +[Term] +id: GO:0062205 +name: miltiradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene." [PMID:24990389, RHEA:33983] +xref: EC:4.2.3.131 +xref: RHEA:33983 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: dph +creation_date: 2020-01-03T14:05:49Z + +[Term] +id: GO:0062206 +name: manoyl oxide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate." [PMID:24990389, RHEA:54516] +xref: EC:4.2.3.190 +xref: RHEA:54516 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: dph +creation_date: 2020-01-03T14:48:52Z + +[Term] +id: GO:0062207 +name: regulation of pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway." [PMID:30610168] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002221 ! pattern recognition receptor signaling pathway +relationship: regulates GO:0002221 ! pattern recognition receptor signaling pathway +created_by: dph +creation_date: 2020-02-03T14:38:53Z + +[Term] +id: GO:0062208 +name: positive regulation of pattern recognition receptor signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway." [PMID:30610168] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0062207 ! regulation of pattern recognition receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002221 ! pattern recognition receptor signaling pathway +relationship: positively_regulates GO:0002221 ! pattern recognition receptor signaling pathway +created_by: dph +creation_date: 2020-02-03T14:45:27Z + +[Term] +id: GO:0062209 +name: spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +namespace: biological_process +def: "Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination." [PMID:25324213, PMID:30217891] +synonym: "crossover interference" RELATED [PMID:30217891] +synonym: "DSB interference" RELATED [] +synonym: "regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [] +synonym: "regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination" EXACT [] +is_a: GO:1905261 ! regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +created_by: dph +creation_date: 2020-02-03T19:19:29Z + +[Term] +id: GO:0062210 +name: shoot regeneration +namespace: biological_process +def: "The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot." [PMID:27143753] +synonym: "shoot system regeneration" EXACT [] +is_a: GO:0031099 ! regeneration +is_a: GO:0048367 ! shoot system development +created_by: dph +creation_date: 2020-02-21T12:38:43Z + +[Term] +id: GO:0062211 +name: root regeneration +namespace: biological_process +def: "The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root." [PMID:27143753] +is_a: GO:0031099 ! regeneration +is_a: GO:0048364 ! root development +created_by: dph +creation_date: 2020-02-21T12:47:41Z + +[Term] +id: GO:0062212 +name: regulation of mitotic DNA replication initiation from early origin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication." [PMID:22279046] +synonym: "regulation of early replication origin firing" EXACT [] +is_a: GO:1903466 ! regulation of mitotic DNA replication initiation +created_by: dph +creation_date: 2020-02-21T19:21:44Z + +[Term] +id: GO:0062213 +name: peroxynitrite isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: peroxynitrite = nitrate." [PMID:30524950] +is_a: GO:0016853 ! isomerase activity +created_by: dph +creation_date: 2020-02-22T13:57:50Z + +[Term] +id: GO:0062223 +name: regulation of somatic muscle development +namespace: biological_process +def: "Any process that regulates the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007525 ! somatic muscle development +relationship: regulates GO:0007525 ! somatic muscle development +created_by: dph +creation_date: 2020-03-13T18:58:37Z + +[Term] +id: GO:0062224 +name: positive regulation of somatic muscle development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0062223 ! regulation of somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007525 ! somatic muscle development +relationship: positively_regulates GO:0007525 ! somatic muscle development +created_by: dph +creation_date: 2020-03-13T19:03:38Z + +[Term] +id: GO:0062225 +name: negative regulation of somatic muscle development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0062223 ! regulation of somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007525 ! somatic muscle development +relationship: negatively_regulates GO:0007525 ! somatic muscle development +created_by: dph +creation_date: 2020-03-13T19:06:27Z + +[Term] +id: GO:0062226 +name: regulation of adult somatic muscle development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of adult somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0062223 ! regulation of somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007527 ! adult somatic muscle development +relationship: regulates GO:0007527 ! adult somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:24:07Z + +[Term] +id: GO:0062227 +name: positive regulation of adult somatic muscle development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of adult somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0062224 ! positive regulation of somatic muscle development +is_a: GO:0062226 ! regulation of adult somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007527 ! adult somatic muscle development +relationship: positively_regulates GO:0007527 ! adult somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:29:41Z + +[Term] +id: GO:0062228 +name: negative regulation of adult somatic muscle development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of adult somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0062225 ! negative regulation of somatic muscle development +is_a: GO:0062226 ! regulation of adult somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007527 ! adult somatic muscle development +relationship: negatively_regulates GO:0007527 ! adult somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:34:38Z + +[Term] +id: GO:0062229 +name: regulation of larval somatic muscle development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of larval somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0062223 ! regulation of somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007526 ! larval somatic muscle development +relationship: regulates GO:0007526 ! larval somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:42:44Z + +[Term] +id: GO:0062230 +name: negative regulation of larval somatic muscle development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of larval somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0062225 ! negative regulation of somatic muscle development +is_a: GO:0062229 ! regulation of larval somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007526 ! larval somatic muscle development +relationship: negatively_regulates GO:0007526 ! larval somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:46:48Z + +[Term] +id: GO:0062231 +name: positive regulation of larval somatic muscle development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of larval somatic muscle development." [PMID:16643882, PMID:25758712] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0062224 ! positive regulation of somatic muscle development +is_a: GO:0062229 ! regulation of larval somatic muscle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007526 ! larval somatic muscle development +relationship: positively_regulates GO:0007526 ! larval somatic muscle development +created_by: dph +creation_date: 2020-03-16T13:49:16Z + +[Term] +id: GO:0062232 +name: prostanoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prostanoids." [PMID:25449649] +is_a: GO:0006692 ! prostanoid metabolic process +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:1901523 ! icosanoid catabolic process +created_by: dph +creation_date: 2020-03-23T15:17:02Z + +[Term] +id: GO:0062233 +name: F2-isoprostane catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of F2-isoprostane." [PMID:16371369, PMID:25449649] +is_a: GO:1901523 ! icosanoid catabolic process +created_by: dph +creation_date: 2020-03-23T15:24:38Z + +[Term] +id: GO:0062234 +name: platelet activating factor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine." [PMID:16371369] +synonym: "2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process" EXACT [] +synonym: "PAF catabolic process" RELATED [] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046469 ! platelet activating factor metabolic process +is_a: GO:0046475 ! glycerophospholipid catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: dph +creation_date: 2020-03-23T15:35:49Z + +[Term] +id: GO:0062235 +name: axonemal basal plate assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate." [PMID:23352055, PMID:30810527] +synonym: "axonemal basal plate formation" NARROW [] +synonym: "axoneme basal plate assembly" EXACT [] +synonym: "basal plate assembly" BROAD [] +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0035082 ! axoneme assembly +created_by: dph +creation_date: 2020-04-16T12:21:35Z + +[Term] +id: GO:0062236 +name: ionocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis." [PMID:17555741] +is_a: GO:0030855 ! epithelial cell differentiation +created_by: dph +creation_date: 2020-04-20T12:30:35Z + +[Term] +id: GO:0062237 +name: protein localization to postsynapse +namespace: biological_process +def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538] +is_a: GO:0035418 ! protein localization to synapse +created_by: dph +creation_date: 2020-04-20T13:58:43Z + +[Term] +id: GO:0062238 +name: Smp focus +namespace: cellular_component +def: "A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I." [PMID:22582262, PMID:31811152] +synonym: "Smp dot" EXACT [] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0000228 ! nuclear chromosome +created_by: dph +creation_date: 2020-04-20T14:23:04Z + +[Term] +id: GO:0062239 +name: heterochromatin-nuclear membrane anchor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization." [PMID:31635174] +is_a: GO:0043495 ! protein-membrane adaptor activity +created_by: dph +creation_date: 2020-04-20T18:20:36Z + +[Term] +id: GO:0062240 +name: euchromatin-nuclear membrane anchor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization." [PMID:31635174] +is_a: GO:0043495 ! protein-membrane adaptor activity +created_by: dph +creation_date: 2020-04-20T18:22:35Z + +[Term] +id: GO:0062241 +name: double strand break-nuclear membrane anchor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair." [PMID:31635174] +synonym: "DNA repair factory" RELATED [] +is_a: GO:0043495 ! protein-membrane adaptor activity +created_by: dph +creation_date: 2020-04-20T18:23:59Z + +[Term] +id: GO:0062242 +name: double membrane vesicle viral factory membrane +namespace: cellular_component +def: "One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory." [PMID:22440839] +synonym: "membrane of double membrane vesicle viral factory" EXACT [] +is_a: GO:0044162 ! host cell cytoplasmic vesicle membrane +intersection_of: GO:0044162 ! host cell cytoplasmic vesicle membrane +intersection_of: part_of GO:0039718 ! double membrane vesicle viral factory +relationship: part_of GO:0039718 ! double membrane vesicle viral factory +created_by: dph +creation_date: 2020-04-20T20:42:28Z + +[Term] +id: GO:0062243 +name: double membrane vesicle viral factory outer membrane +namespace: cellular_component +def: "The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory." [PMID:22440839] +synonym: "outer membrane of double membrane vesicle viral factory" EXACT [] +is_a: GO:0062242 ! double membrane vesicle viral factory membrane +created_by: dph +creation_date: 2020-04-20T20:47:40Z + +[Term] +id: GO:0062244 +name: double membrane vesicle viral factory lumen +namespace: cellular_component +def: "The volume surrounded by the inner membrane of a double membrane vesicle viral factory." [PMID:22440839] +synonym: "lumen of double membrane vesicle viral factory" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0039718 ! double membrane vesicle viral factory +created_by: dph +creation_date: 2020-04-20T20:53:30Z + +[Term] +id: GO:0062245 +name: double membrane vesicle viral factory inner membrane +namespace: cellular_component +def: "The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory." [PMID:22440839] +synonym: "inner membrane of double membrane vesicle viral factory" EXACT [] +is_a: GO:0062242 ! double membrane vesicle viral factory membrane +created_by: dph +creation_date: 2020-04-20T20:55:49Z + +[Term] +id: GO:0062246 +name: exocytic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by an exocytic vesicle." [PMID:27384577] +is_a: GO:0098566 ! transport vesicle lumen +intersection_of: GO:0098566 ! transport vesicle lumen +intersection_of: part_of GO:0070382 ! exocytic vesicle +relationship: part_of GO:0070382 ! exocytic vesicle +created_by: dph +creation_date: 2020-04-27T12:10:09Z + +[Term] +id: GO:0062247 +name: chloroplast vesicle +namespace: cellular_component +def: "A intracellular vesicle that is part of a chloroplast." [PMID:32245810] +is_a: GO:0031410 ! cytoplasmic vesicle +intersection_of: GO:0097708 ! intracellular vesicle +intersection_of: part_of GO:0009507 ! chloroplast +relationship: part_of GO:0009507 ! chloroplast +created_by: dph +creation_date: 2020-05-01T12:10:16Z + +[Term] +id: GO:0065001 +name: specification of axis polarity +namespace: biological_process +def: "The pattern specification process in which the polarity of a body or organ axis is established and maintained." [GOC:mah] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0009798 ! axis specification + +[Term] +id: GO:0065002 +name: intracellular protein transmembrane transport +namespace: biological_process +def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "intracellular membrane translocation of a protein" EXACT [] +synonym: "intracellular protein membrane transport" EXACT [] +synonym: "intracellular protein transport across a membrane" EXACT [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0065003 +name: protein-containing complex assembly +namespace: biological_process +alt_id: GO:0006461 +def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_metagenomics +subset: goslim_pir +subset: goslim_pombe +synonym: "chaperone activity" RELATED [] +synonym: "macromolecular complex assembly" RELATED [] +synonym: "macromolecule complex assembly" RELATED [] +synonym: "protein complex assembly" RELATED [] +synonym: "protein complex formation" RELATED [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0043933 ! protein-containing complex subunit organization + +[Term] +id: GO:0065004 +name: protein-DNA complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl] +synonym: "DNA-protein complex assembly" EXACT [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly +is_a: GO:0071824 ! protein-DNA complex subunit organization + +[Term] +id: GO:0065005 +name: protein-lipid complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex." [GOC:jl] +is_a: GO:0065003 ! protein-containing complex assembly +is_a: GO:0071825 ! protein-lipid complex subunit organization + +[Term] +id: GO:0065007 +name: biological regulation +namespace: biological_process +def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] +subset: gocheck_do_not_annotate +subset: goslim_pir +synonym: "regulation" BROAD [] +is_a: GO:0008150 ! biological_process + +[Term] +id: GO:0065008 +name: regulation of biological quality +namespace: biological_process +def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] +subset: goslim_pir +synonym: "regulation of biological attribute" EXACT [] +synonym: "regulation of biological characteristic" EXACT [] +is_a: GO:0065007 ! biological regulation + +[Term] +id: GO:0065009 +name: regulation of molecular function +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] +subset: gocheck_do_not_annotate +subset: goslim_pir +subset: goslim_plant +synonym: "regulation of a molecular function" EXACT [] +is_a: GO:0065007 ! biological regulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003674 ! molecular_function +relationship: regulates GO:0003674 ! molecular_function + +[Term] +id: GO:0065010 +name: extracellular membrane-bounded organelle +namespace: cellular_component +def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] +synonym: "extracellular membrane-enclosed organelle" EXACT [] +is_a: GO:0043227 ! membrane-bounded organelle +is_a: GO:0043230 ! extracellular organelle + +[Term] +id: GO:0070001 +name: aspartic-type peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0070002 +name: glutamic-type peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0070003 +name: threonine-type peptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +is_a: GO:0070011 ! peptidase activity, acting on L-amino acid peptides + +[Term] +id: GO:0070004 +name: cysteine-type exopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE] +is_a: GO:0008234 ! cysteine-type peptidase activity +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0070005 +name: cysteine-type aminopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +xref: EC:3.4.18 +is_a: GO:0004177 ! aminopeptidase activity +is_a: GO:0070004 ! cysteine-type exopeptidase activity + +[Term] +id: GO:0070006 +name: metalloaminopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +is_a: GO:0004177 ! aminopeptidase activity +is_a: GO:0008235 ! metalloexopeptidase activity + +[Term] +id: GO:0070007 +name: glutamic-type endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE] +is_a: GO:0004175 ! endopeptidase activity +is_a: GO:0070002 ! glutamic-type peptidase activity + +[Term] +id: GO:0070008 +name: serine-type exopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE, ISBN:0716720094] +xref: EC:3.4.21 +is_a: GO:0008236 ! serine-type peptidase activity +is_a: GO:0008238 ! exopeptidase activity + +[Term] +id: GO:0070009 +name: serine-type aminopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094] +is_a: GO:0004177 ! aminopeptidase activity +is_a: GO:0070008 ! serine-type exopeptidase activity + +[Term] +id: GO:0070010 +name: peptidase activity, acting on D-amino acid peptides +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds formed between D-amino acids." [GOC:mah] +is_a: GO:0008233 ! peptidase activity + +[Term] +id: GO:0070011 +name: peptidase activity, acting on L-amino acid peptides +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds formed between L-amino acids." [GOC:mah] +xref: Reactome:R-HSA-3065958 "An unknown protease degrades ACACA" +xref: Reactome:R-HSA-3065959 "An unknown protease degrades hCBXs" +xref: Reactome:R-HSA-4167501 "An unknown protease degrades ACACB" +xref: Reactome:R-HSA-6803060 "DCD(63-110) is processed to DCD(63-109)" +is_a: GO:0008233 ! peptidase activity + +[Term] +id: GO:0070012 +name: oligopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds." [GOC:mah, ISBN:0198506732] +is_a: GO:0008233 ! peptidase activity + +[Term] +id: GO:0070013 +name: intracellular organelle lumen +namespace: cellular_component +def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah] +subset: goslim_mouse +is_a: GO:0043233 ! organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0043229 ! intracellular organelle +relationship: part_of GO:0043229 ! intracellular organelle + +[Term] +id: GO:0070014 +name: sucrase-isomaltase complex +namespace: cellular_component +def: "A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities." [PMID:3366777] +synonym: "oligo-1,6-glucosidase complex" RELATED [] +xref: Wikipedia:Sucrase-isomaltase +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1902687 ! glucosidase complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0070016 +name: armadillo repeat domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation." [GOC:BHF, GOC:mah, GOC:vk, InterPro:IPR000225] +synonym: "Arm repeat domain binding" EXACT [] +synonym: "armadillo domain binding" EXACT [] +synonym: "armadillo repeat binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0070017 +name: alphav-beta3 integrin-thrombospondin complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin." [PMID:2478219] +synonym: "ITGAV-ITGB3-THBS1 complex" NARROW [CORUM:2846] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070018 +name: obsolete transforming growth factor beta type I receptor homodimeric complex +namespace: cellular_component +def: "OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers." [Reactome:R-HSA-170864] +comment: This term was made obsolete because it does not represent a physiological complex. +synonym: "TGF-beta type I receptor complex" EXACT [] +synonym: "TGF-beta type I receptor dimer" EXACT [Reactome:R-HSA-170864] +synonym: "TGFBR1 homodimer" EXACT [Reactome:R-HSA-170864] +synonym: "transforming growth factor beta type I receptor complex" EXACT [GOC:bf] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12676 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0070019 +name: obsolete transforming growth factor beta type II receptor homodimeric complex +namespace: cellular_component +def: "OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers." [Reactome:R-HSA-170866] +comment: This term was made obsolete because it does not represent a physiological complex. +synonym: "TGF-beta type II receptor complex" EXACT [] +synonym: "TGF-beta type II receptor dimer" EXACT [Reactome:R-HSA-170866] +synonym: "TGFBR2 homodimer" EXACT [Reactome:R-HSA-170866] +synonym: "transforming growth factor beta type II receptor complex" EXACT [GOC:bf] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12676 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0070020 +name: obsolete transforming growth factor beta1-type II receptor complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer." [Reactome:R-HSA-170865] +comment: This term was made obsolete because it does not represent a physiological complex. +synonym: "TGF-beta receptor II-TGF-beta1 complex" EXACT [] +synonym: "TGF-beta1-type II receptor complex" EXACT [Reactome:R-HSA-170865] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12676 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0070021 +name: transforming growth factor beta ligand-receptor complex +namespace: cellular_component +def: "A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand." [Reactome:R-HSA-170840] +synonym: "TGF-beta 1:type II receptor:type I receptor complex" NARROW [Reactome:R-HSA-170840] +synonym: "TGF-beta ligand-receptor complex" EXACT [] +synonym: "TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex" NARROW [] +synonym: "TGF-beta1 ligand-receptor complex" NARROW [] +synonym: "TGF-beta1-beta2 ligand-receptor complex" NARROW [] +synonym: "TGF-beta1-type II receptor-type I receptor complex" NARROW [] +synonym: "TGF-beta2 ligand-receptor complex" NARROW [] +synonym: "TGFb ligand-receptor complex" EXACT [] +synonym: "TGFbeta ligand-receptor complex" EXACT [] +synonym: "TGFbeta1 ligand-receptor complex" NARROW [] +synonym: "TGFbeta1-beta2 ligand-receptor complex" NARROW [] +synonym: "TGFbeta2 ligand-receptor complex" NARROW [] +synonym: "transforming growth factor beta1-type II receptor-type I receptor complex" NARROW [] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +is_a: GO:1902554 ! serine/threonine protein kinase complex + +[Term] +id: GO:0070022 +name: obsolete transforming growth factor beta receptor complex +namespace: cellular_component +def: "OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers." [GOC:mah, Reactome:R-HSA-170864, Reactome:R-HSA-170866] +comment: This term was made obsolete because it does not represent a physiological complex. +synonym: "TGF-beta receptor complex" BROAD [] +synonym: "transforming growth factor beta receptor complex" EXACT [GOC:bf] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12676 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0070023 +name: interleukin-12-interleukin-12 receptor complex +namespace: cellular_component +def: "A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer." [PMID:11900991] +synonym: "IL12-IL12 receptor complex" EXACT [] +synonym: "IL12B-IL12RB1-IL12RB2 complex" NARROW [CORUM:2020] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070024 +name: CD19-Vav-PIK3R1 complex +namespace: cellular_component +def: "A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K)." [PMID:7528218] +synonym: "CD19-Vav-PI 3-kinase (p85 subunit) complex" EXACT [CORUM:2574] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070025 +name: carbon monoxide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with carbon monoxide (CO)." [GOC:ecd] +synonym: "CO binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0042165 ! neurotransmitter binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0070026 +name: nitric oxide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with nitric oxide (NO)." [GOC:ecd] +synonym: "nitrogen monoxide binding" EXACT [] +synonym: "nitrosyl binding" EXACT [CHEBI:16480] +synonym: "NO binding" EXACT [] +is_a: GO:0005488 ! binding + +[Term] +id: GO:0070027 +name: carbon monoxide sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO)." [GOC:ecd] +is_a: GO:0070025 ! carbon monoxide binding +is_a: GO:0140299 ! small molecule sensor activity + +[Term] +id: GO:0070028 +name: obsolete regulation of transcription by carbon monoxide +namespace: biological_process +def: "OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription." [GOC:ecd] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of transcription by CO" EXACT [] +is_obsolete: true + +[Term] +id: GO:0070029 +name: alphav-beta3 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin." [PMID:7532190] +synonym: "ITGAV-ITGB3-SPP1 complex" NARROW [CORUM:2358] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070030 +name: alphav-beta1 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin." [PMID:7592829] +synonym: "ITGAV-ITGB1-SPP1 complex" NARROW [CORUM:2885] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070031 +name: alphav-beta5 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin." [PMID:7592829] +synonym: "ITGAV-ITGB5-SPP1 complex" NARROW [CORUM:2347] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070032 +name: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof)." [PMID:7553862] +synonym: "SNARE complex (Vamp2, Snap25, Stx1a, Cplx1)" NARROW [CORUM:795] +synonym: "Vamp2-Snap25-Stx1a-Cplx1 complex" NARROW [CORUM:795] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070033 +name: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof)." [PMID:7553862] +synonym: "SNARE complex (Vamp2, Snap25, Stx1a, Cplx2)" NARROW [CORUM:796] +synonym: "Vamp2-Snap25-Stx1a-Cplx2 complex" NARROW [CORUM:796] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070034 +name: telomerase RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the telomerase RNA template." [GOC:krc, PMID:16884717] +synonym: "TERC binding" RELATED [GOC:dph] +is_a: GO:0003723 ! RNA binding + +[Term] +id: GO:0070035 +name: obsolete purine NTP-dependent helicase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix." [GOC:mah] +comment: The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term. +is_obsolete: true + +[Term] +id: GO:0070036 +name: obsolete GTP-dependent helicase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix." [GOC:mah] +comment: The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo). +is_obsolete: true + +[Term] +id: GO:0070037 +name: rRNA (pseudouridine) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule." [GOC:imk, GOC:mah] +xref: Reactome:R-HSA-6790906 "EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248" +is_a: GO:0008649 ! rRNA methyltransferase activity + +[Term] +id: GO:0070038 +name: rRNA (pseudouridine-N3-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine." [GOC:imk, GOC:mah] +is_a: GO:0070037 ! rRNA (pseudouridine) methyltransferase activity + +[Term] +id: GO:0070039 +name: rRNA (guanosine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine." [GOC:imk, GOC:mah] +xref: Reactome:R-HSA-6793096 "MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370" +xref: Reactome:R-HSA-6793122 "MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145" +is_a: GO:0016435 ! rRNA (guanine) methyltransferase activity +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity +relationship: part_of GO:0000451 ! rRNA 2'-O-methylation + +[Term] +id: GO:0070040 +name: rRNA (adenine-C2-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA." [GOC:imk, PMID:20007606, PMID:20184321, PMID:21368151, PMID:21415317, PMID:21527678] +xref: EC:2.1.1.192 +xref: MetaCyc:RXN-11586 +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity + +[Term] +id: GO:0070041 +name: rRNA (uridine-C5-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine." [GOC:imk, GOC:mah] +is_a: GO:0008169 ! C-methyltransferase activity +is_a: GO:0016436 ! rRNA (uridine) methyltransferase activity + +[Term] +id: GO:0070042 +name: rRNA (uridine-N3-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine." [GOC:imk, GOC:mah] +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016436 ! rRNA (uridine) methyltransferase activity + +[Term] +id: GO:0070043 +name: rRNA (guanine-N7-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine." [GOC:imk, GOC:mah] +xref: Reactome:R-HSA-6790982 "WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639" +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016435 ! rRNA (guanine) methyltransferase activity +relationship: part_of GO:0070476 ! rRNA (guanine-N7)-methylation + +[Term] +id: GO:0070044 +name: synaptobrevin 2-SNAP-25-syntaxin-1a complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof)." [PMID:10336434] +synonym: "Snap25-Stx1a-Vamp2 complex" NARROW [] +synonym: "SNARE complex (Snap25, Stx1a, Vamp2)" NARROW [CORUM:998] +synonym: "SNARE complex (Stx1a, SNAP25, VAMP)" NARROW [CORUM:841] +synonym: "Stx1a-SNAP25-VAMP complex" NARROW [CORUM:841] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070045 +name: synaptobrevin 2-SNAP-25-syntaxin-2 complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof)." [PMID:10336434] +synonym: "SNARE complex (Stx2, Snap25, Vamp2)" NARROW [CORUM:851] +synonym: "Stx2-Snap25-Vamp2 complex" NARROW [CORUM:851] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070046 +name: synaptobrevin 2-SNAP-25-syntaxin-3 complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof)." [PMID:10336434] +synonym: "SNARE complex (Stx3, Snap25, Vamp2)" NARROW [CORUM:852] +synonym: "Stx3-Snap25-Vamp2 complex" NARROW [CORUM:852] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070047 +name: synaptobrevin 2-SNAP-25-syntaxin-4 complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof)." [PMID:10336434] +synonym: "SNARE complex (Stx4, Snap25, Vamp2)" NARROW [CORUM:853] +synonym: "Stx4-Snap25-Vamp2 complex" NARROW [CORUM:853] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070048 +name: endobrevin-SNAP-25-syntaxin-1a complex +namespace: cellular_component +def: "A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof)." [PMID:10336434] +synonym: "SNARE complex (Stx1a, Snap25, Vamp8)" NARROW [CORUM:854] +synonym: "Stx1a-Snap25-Vamp8 complex" NARROW [CORUM:854] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070049 +name: endobrevin-SNAP-25-syntaxin-2 complex +namespace: cellular_component +def: "A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof)." [PMID:10336434] +synonym: "SNARE complex (Stx2, Snap25, Vamp8)" NARROW [CORUM:855] +synonym: "Stx2-Snap25-Vamp8 complex" NARROW [CORUM:855] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070050 +name: neuron cellular homeostasis +namespace: biological_process +def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah] +synonym: "neuron maintenance" EXACT [] +is_a: GO:0019725 ! cellular homeostasis +is_a: GO:0060249 ! anatomical structure homeostasis + +[Term] +id: GO:0070051 +name: fibrinogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade." [GOC:BHF, GOC:mah, GOC:vk] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0070052 +name: collagen V binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type V collagen trimer." [GOC:BHF, GOC:mah] +is_a: GO:0005518 ! collagen binding + +[Term] +id: GO:0070053 +name: thrombospondin receptor activity +namespace: molecular_function +def: "Combining with thrombospondin and transmitting the signal to initiate a change in cell activity." [GOC:BHF, GOC:signaling, GOC:vk] +is_a: GO:0038023 ! signaling receptor activity + +[Term] +id: GO:0070054 +name: mRNA splicing, via endonucleolytic cleavage and ligation +namespace: biological_process +alt_id: GO:0061012 +def: "Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons." [GOC:krc, GOC:mah] +comment: Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis. +synonym: "cytosolic mRNA splicing" RELATED [] +is_a: GO:0000394 ! RNA splicing, via endonucleolytic cleavage and ligation +is_a: GO:0006397 ! mRNA processing + +[Term] +id: GO:0070055 +name: obsolete mRNA endonucleolytic cleavage involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response." [GOC:bf, GOC:krc, GOC:mah, PMID:10357823] +comment: The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498). +synonym: "ERN1-mediated XBP-1 mRNA cleavage" RELATED [HGNC:3449] +synonym: "HAC1 mRNA cleavage" NARROW [GOC:bf] +synonym: "HAC1-type intron splice site recognition and cleavage" NARROW [] +synonym: "IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:bf] +synonym: "XBP1 mRNA cleavage" NARROW [GOC:bf] +is_obsolete: true +consider: GO:0036498 + +[Term] +id: GO:0070056 +name: prospore membrane leading edge +namespace: cellular_component +def: "The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization." [GOC:mah, PMID:14702385] +synonym: "forespore membrane leading edge" EXACT [] +is_a: GO:0098589 ! membrane region +relationship: part_of GO:0005628 ! prospore membrane + +[Term] +id: GO:0070057 +name: prospore membrane spindle pole body attachment site +namespace: cellular_component +def: "The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus." [GOC:mah, PMID:14702385] +synonym: "forespore membrane SPB attachment site" EXACT [] +synonym: "forespore membrane spindle pole body attachment site" EXACT [] +synonym: "prospore membrane SPB attachment site" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005628 ! prospore membrane + +[Term] +id: GO:0070058 +name: tRNA gene clustering +namespace: biological_process +def: "The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae." [GOC:jh, GOC:mah, PMID:18708579] +is_a: GO:0051276 ! chromosome organization + +[Term] +id: GO:0070059 +name: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:mah, GOC:mtg_apoptosis, PMID:18701708] +synonym: "apoptosis in response to endoplasmic reticulum stress" BROAD [] +synonym: "apoptosis in response to ER stress" EXACT [] +synonym: "apoptosis triggered by ER stress" EXACT [] +synonym: "endoplasmic reticulum stress-induced apoptosis" EXACT [] +synonym: "ER stress-induced apoptosis" EXACT [] +synonym: "intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway + +[Term] +id: GO:0070060 +name: 'de novo' actin filament nucleation +namespace: biological_process +def: "The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament." [GOC:mah, PMID:17477841] +synonym: "formin-mediated actin filament nucleation" NARROW [] +synonym: "unbranched actin filament nucleation" RELATED [] +is_a: GO:0045010 ! actin nucleation + +[Term] +id: GO:0070061 +name: fructose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose." [CHEBI:28757, GOC:BHF, GOC:mah] +is_a: GO:0048029 ! monosaccharide binding + +[Term] +id: GO:0070062 +name: extracellular exosome +namespace: cellular_component +def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] +synonym: "exosome" EXACT [GOC:pr] +synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles] +is_a: GO:1903561 ! extracellular vesicle +relationship: part_of GO:0005615 ! extracellular space + +[Term] +id: GO:0070063 +name: RNA polymerase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA polymerase molecule or complex." [GOC:BHF, GOC:mah, GOC:txnOH] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0070064 +name: proline-rich region binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein." [GOC:mah] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0070065 +name: cellubrevin-VAMP4-syntaxin-16 complex +namespace: cellular_component +def: "A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof)." [PMID:11839770] +synonym: "SNARE complex (Vamp3, Vamp4, Stx16)" NARROW [CORUM:875] +synonym: "Vamp3-Vamp4-Stx16 complex" NARROW [CORUM:875] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070066 +name: cellubrevin-VAMP4-endobrevin-syntaxin-6 complex +namespace: cellular_component +def: "A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof)." [PMID:11839770] +synonym: "SNARE complex (Vamp3, Vamp4, Vam8, Stx6)" NARROW [CORUM:874] +synonym: "Vamp3-Vamp4-Vam8-Stx6 complex" NARROW [CORUM:874] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070067 +name: syntaxin-6-syntaxin-16-Vti1a complex +namespace: cellular_component +def: "A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof)." [PMID:11839770] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070068 +name: VAMP4-syntaxin-6-syntaxin-16-Vti1a complex +namespace: cellular_component +def: "A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof)." [PMID:11839770] +synonym: "SNARE complex (Vamp4, Stx6, Stx16, Vti1a)" NARROW [CORUM:877] +synonym: "Vamp4-Stx6-Stx16-Vti1a complex" RELATED [CORUM:877] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070069 +name: cytochrome complex +namespace: cellular_component +def: "A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions." [GOC:mah] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0070070 +name: proton-transporting V-type ATPase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient." [GOC:mah] +synonym: "V-ATPase assembly" RELATED [] +synonym: "V-ATPase complex assembly" RELATED [] +is_a: GO:0070071 ! proton-transporting two-sector ATPase complex assembly + +[Term] +id: GO:0070071 +name: proton-transporting two-sector ATPase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane." [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0070072 +name: vacuolar proton-transporting V-type ATPase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane." [GOC:BHF, GOC:mah] +synonym: "V-ATPase assembly" BROAD [] +synonym: "V-ATPase complex assembly" BROAD [] +is_a: GO:0070070 ! proton-transporting V-type ATPase complex assembly + +[Term] +id: GO:0070073 +name: clustering of voltage-gated calcium channels +namespace: biological_process +def: "The process in which voltage-gated calcium channels become localized together in high densities." [GOC:BHF, GOC:sart, PMID:18385325] +synonym: "clustering of voltage gated calcium channels" EXACT [] +synonym: "clustering of voltage-dependent calcium channels" EXACT [] +synonym: "voltage-gated calcium channel clustering" EXACT [] +is_a: GO:0045161 ! neuronal ion channel clustering + +[Term] +id: GO:0070074 +name: mononeme +namespace: cellular_component +def: "A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts." [GOC:BHF, PMID:18048320] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0020007 ! apical complex + +[Term] +id: GO:0070075 +name: tear secretion +namespace: biological_process +def: "The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium." [GOC:rph] +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0032941 ! secretion by tissue + +[Term] +id: GO:0070076 +name: histone lysine demethylation +namespace: biological_process +def: "The modification of a histone by the removal of a methyl group from a lysine residue." [GOC:mah] +is_a: GO:0016577 ! histone demethylation + +[Term] +id: GO:0070077 +name: histone arginine demethylation +namespace: biological_process +def: "The modification of a histone by the removal of a methyl group from an arginine residue." [GOC:mah] +is_a: GO:0016577 ! histone demethylation + +[Term] +id: GO:0070078 +name: histone H3-R2 demethylation +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone." [GOC:BHF, GOC:vk] +is_a: GO:0070077 ! histone arginine demethylation + +[Term] +id: GO:0070079 +name: histone H4-R3 demethylation +namespace: biological_process +def: "The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone." [GOC:BHF, GOC:vk] +is_a: GO:0070077 ! histone arginine demethylation + +[Term] +id: GO:0070080 +name: titin Z domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34." [GOC:mah, InterPro:IPR015129] +synonym: "Z repeat domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0070081 +name: clathrin-sculpted monoamine transport vesicle +namespace: cellular_component +def: "A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines." [GOC:mg2] +synonym: "clathrin sculpted monoamine constitutive secretory pathway transport vesicle" EXACT [] +synonym: "clathrin sculpted monoamine transport vesicle" EXACT [GOC:sl] +is_a: GO:0030133 ! transport vesicle +is_a: GO:0060198 ! clathrin-sculpted vesicle + +[Term] +id: GO:0070082 +name: clathrin-sculpted monoamine transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle." [GOC:mg2] +synonym: "clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen" EXACT [] +synonym: "clathrin sculpted monoamine transport vesicle lumen" EXACT [GOC:sl] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0070081 ! clathrin-sculpted monoamine transport vesicle + +[Term] +id: GO:0070083 +name: clathrin-sculpted monoamine transport vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle." [GOC:mg2] +synonym: "clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane" EXACT [] +synonym: "clathrin sculpted monoamine transport vesicle membrane" EXACT [GOC:sl] +is_a: GO:0030658 ! transport vesicle membrane +is_a: GO:0030665 ! clathrin-coated vesicle membrane +relationship: part_of GO:0070081 ! clathrin-sculpted monoamine transport vesicle + +[Term] +id: GO:0070084 +name: protein initiator methionine removal +namespace: biological_process +def: "The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein." [GOC:imk, GOC:mah] +synonym: "removal of initiator methionine from protein" EXACT [] +is_a: GO:0006464 ! cellular protein modification process + +[Term] +id: GO:0070085 +name: glycosylation +namespace: biological_process +def: "The covalent attachment and further modification of carbohydrate residues to a substrate molecule." [GOC:hjd, GOC:mah] +xref: Wikipedia:Glycosylation +is_a: GO:0008152 ! metabolic process + +[Term] +id: GO:0070086 +name: ubiquitin-dependent endocytosis +namespace: biological_process +def: "Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded." [GOC:jp, GOC:mah, PMID:9409540] +synonym: "ubiquitin-mediated endocytosis" EXACT [GOC:jp] +is_a: GO:0006897 ! endocytosis +is_a: GO:0015031 ! protein transport +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0098657 ! import into cell + +[Term] +id: GO:0070087 +name: chromo shadow domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain." [GOC:BHF, GOC:vk, InterPro:IPR008251, PMID:7667093] +synonym: "chromoshadow domain binding" EXACT [GOC:vk] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0070088 +name: PHA granule +namespace: cellular_component +def: "An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR." [GOC:mah, PMID:15762612] +synonym: "PHB granule" NARROW [] +synonym: "polyhydroxyalkanoate granule" EXACT [] +is_a: GO:0016234 ! inclusion body +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0070089 +name: chloride-activated potassium channel activity +namespace: molecular_function +def: "Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient." [GOC:kmv, GOC:mtg_transport] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0022839 ! ion gated channel activity + +[Term] +id: GO:0070090 +name: metaphase plate +namespace: cellular_component +def: "The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division." [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0070091 +name: glucagon secretion +namespace: biological_process +def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0070092 +name: regulation of glucagon secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070091 ! glucagon secretion +relationship: regulates GO:0070091 ! glucagon secretion + +[Term] +id: GO:0070093 +name: negative regulation of glucagon secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] +synonym: "down regulation of glucagon secretion" EXACT [] +synonym: "down-regulation of glucagon secretion" EXACT [] +synonym: "downregulation of glucagon secretion" EXACT [] +synonym: "inhibition of glucagon secretion" NARROW [] +is_a: GO:0070092 ! regulation of glucagon secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070091 ! glucagon secretion +relationship: negatively_regulates GO:0070091 ! glucagon secretion + +[Term] +id: GO:0070094 +name: positive regulation of glucagon secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] +synonym: "activation of glucagon secretion" NARROW [] +synonym: "stimulation of glucagon secretion" NARROW [] +synonym: "up regulation of glucagon secretion" EXACT [] +synonym: "up-regulation of glucagon secretion" EXACT [] +synonym: "upregulation of glucagon secretion" EXACT [] +is_a: GO:0070092 ! regulation of glucagon secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070091 ! glucagon secretion +relationship: positively_regulates GO:0070091 ! glucagon secretion + +[Term] +id: GO:0070095 +name: fructose-6-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with fructose 6-phosphate." [GOC:mah] +synonym: "D-fructose 6-phosphate binding" NARROW [] +synonym: "fructose 6-phosphate binding" EXACT [] +is_a: GO:0043168 ! anion binding +is_a: GO:0097367 ! carbohydrate derivative binding + +[Term] +id: GO:0070096 +name: mitochondrial outer membrane translocase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex." [GOC:BHF, GOC:vk] +synonym: "TOM complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0007008 ! outer mitochondrial membrane organization + +[Term] +id: GO:0070097 +name: delta-catenin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the delta subunit of the catenin complex." [GOC:rph] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0070098 +name: chemokine-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling] +synonym: "chemokine-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:1990869 ! cellular response to chemokine + +[Term] +id: GO:0070099 +name: regulation of chemokine-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah] +synonym: "regulation of chemokine-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070098 ! chemokine-mediated signaling pathway +relationship: regulates GO:0070098 ! chemokine-mediated signaling pathway + +[Term] +id: GO:0070100 +name: negative regulation of chemokine-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah] +synonym: "negative regulation of chemokine-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0070099 ! regulation of chemokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070098 ! chemokine-mediated signaling pathway +relationship: negatively_regulates GO:0070098 ! chemokine-mediated signaling pathway + +[Term] +id: GO:0070101 +name: positive regulation of chemokine-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor." [GOC:mah] +synonym: "positive regulation of chemokine-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0070099 ! regulation of chemokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070098 ! chemokine-mediated signaling pathway +relationship: positively_regulates GO:0070098 ! chemokine-mediated signaling pathway + +[Term] +id: GO:0070102 +name: interleukin-6-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:add, GOC:BHF, GOC:mah, GOC:signaling] +synonym: "IL-6-mediated signaling pathway" RELATED [] +synonym: "interleukin-6-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071354 ! cellular response to interleukin-6 + +[Term] +id: GO:0070103 +name: regulation of interleukin-6-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "regulation of IL-6-mediated signaling pathway" EXACT [GOC:mah] +synonym: "regulation of interleukin-6-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070102 ! interleukin-6-mediated signaling pathway +relationship: regulates GO:0070102 ! interleukin-6-mediated signaling pathway + +[Term] +id: GO:0070104 +name: negative regulation of interleukin-6-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "negative regulation of IL-6-mediated signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of interleukin-6-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0070103 ! regulation of interleukin-6-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070102 ! interleukin-6-mediated signaling pathway +relationship: negatively_regulates GO:0070102 ! interleukin-6-mediated signaling pathway + +[Term] +id: GO:0070105 +name: positive regulation of interleukin-6-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "positive regulation of IL-6-mediated signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of interleukin-6-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0070103 ! regulation of interleukin-6-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070102 ! interleukin-6-mediated signaling pathway +relationship: positively_regulates GO:0070102 ! interleukin-6-mediated signaling pathway + +[Term] +id: GO:0070106 +name: interleukin-27-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:add, GOC:BHF, GOC:mah, GOC:signaling] +synonym: "IL-27-mediated signaling pathway" EXACT [GOC:mah] +synonym: "IL27RA/IL6ST signaling pathway" EXACT [GOC:add] +synonym: "interleukin-27-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0070107 +name: regulation of interleukin-27-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "regulation of IL-27-mediated signaling pathway" EXACT [GOC:mah] +synonym: "regulation of IL27RA/IL6ST signaling pathway" EXACT [GOC:add] +synonym: "regulation of interleukin-27-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070106 ! interleukin-27-mediated signaling pathway +relationship: regulates GO:0070106 ! interleukin-27-mediated signaling pathway + +[Term] +id: GO:0070108 +name: negative regulation of interleukin-27-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "negative regulation of IL-27-mediated signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of IL27RA/IL6ST signaling pathway" EXACT [GOC:add] +synonym: "negative regulation of interleukin-27-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0070107 ! regulation of interleukin-27-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070106 ! interleukin-27-mediated signaling pathway +relationship: negatively_regulates GO:0070106 ! interleukin-27-mediated signaling pathway + +[Term] +id: GO:0070109 +name: positive regulation of interleukin-27-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor." [GOC:BHF, GOC:mah] +synonym: "positive regulation of IL-27-mediated signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of IL27RA/IL6ST signaling pathway" EXACT [GOC:add] +synonym: "positive regulation of interleukin-27-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0070107 ! regulation of interleukin-27-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070106 ! interleukin-27-mediated signaling pathway +relationship: positively_regulates GO:0070106 ! interleukin-27-mediated signaling pathway + +[Term] +id: GO:0070110 +name: ciliary neurotrophic factor receptor complex +namespace: cellular_component +def: "A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR." [GOC:BHF, GOC:mah, GOC:rl, PMID:12707266] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane + +[Term] +id: GO:0070111 +name: organellar chromatophore +namespace: cellular_component +def: "A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora." [GOC:expert_mm, PMID:18356055] +synonym: "Paulinella-type chromatophore" EXACT [] +is_a: GO:0043660 ! bacteroid-containing symbiosome + +[Term] +id: GO:0070112 +name: organellar chromatophore membrane +namespace: cellular_component +def: "Either of the lipid bilayers that surround an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore membrane" EXACT [GOC:mah] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +relationship: part_of GO:0070111 ! organellar chromatophore + +[Term] +id: GO:0070113 +name: organellar chromatophore inner membrane +namespace: cellular_component +def: "The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore inner membrane" EXACT [GOC:mah] +is_a: GO:0070112 ! organellar chromatophore membrane + +[Term] +id: GO:0070114 +name: organellar chromatophore outer membrane +namespace: cellular_component +def: "The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore outer membrane" EXACT [GOC:mah] +is_a: GO:0043661 ! peribacteroid membrane +is_a: GO:0070112 ! organellar chromatophore membrane + +[Term] +id: GO:0070115 +name: organellar chromatophore intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers that surround an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore intermembrane space" EXACT [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0070111 ! organellar chromatophore + +[Term] +id: GO:0070116 +name: organellar chromatophore thylakoid +namespace: cellular_component +def: "A thylakoid located in an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore thylakoid" EXACT [GOC:mah] +is_a: GO:0009579 ! thylakoid +relationship: part_of GO:0070111 ! organellar chromatophore + +[Term] +id: GO:0070117 +name: organellar chromatophore thylakoid lumen +namespace: cellular_component +def: "The volume enclosed by an organellar chromatophore thylakoid membrane." [GOC:mah] +synonym: "Paulinella-type chromatophore thylakoid lumen" EXACT [GOC:mah] +is_a: GO:0031977 ! thylakoid lumen +relationship: part_of GO:0070116 ! organellar chromatophore thylakoid + +[Term] +id: GO:0070118 +name: organellar chromatophore thylakoid membrane +namespace: cellular_component +def: "The lipid bilayer membrane of any thylakoid within an organellar chromatophore." [GOC:mah] +synonym: "Paulinella-type chromatophore thylakoid membrane" EXACT [GOC:mah] +is_a: GO:0042651 ! thylakoid membrane +relationship: part_of GO:0070116 ! organellar chromatophore thylakoid + +[Term] +id: GO:0070119 +name: ciliary neurotrophic factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor." [GOC:BHF, GOC:mah] +synonym: "CNTF binding" EXACT [GOC:mah] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0070120 +name: ciliary neurotrophic factor-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mah] +synonym: "ciliary neurotrophic factor-mediated signalling pathway" EXACT [GOC:mah] +synonym: "CNTF-mediated signaling pathway" EXACT [GOC:rl] +is_a: GO:0019221 ! cytokine-mediated signaling pathway + +[Term] +id: GO:0070121 +name: Kupffer's vesicle development +namespace: biological_process +def: "The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period." [GOC:dgh] +synonym: "KV development" EXACT [GOC:dgh] +is_a: GO:0048856 ! anatomical structure development + +[Term] +id: GO:0070122 +name: isopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond)." [GOC:mah, Wikipedia:Isopeptidase] +is_a: GO:0008233 ! peptidase activity + +[Term] +id: GO:0070123 +name: transforming growth factor beta receptor activity, type III +namespace: molecular_function +def: "Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors." [GOC:BHF, GOC:mah, PMID:9759503] +synonym: "betaglycan" NARROW [] +synonym: "endoglin" NARROW [] +synonym: "transforming growth factor beta ligand binding to type III receptor" RELATED [] +synonym: "type III TGF-beta receptor activity" EXACT [] +synonym: "type III TGFbeta receptor activity" EXACT [] +synonym: "type III transforming growth factor beta receptor activity" EXACT [] +is_a: GO:0005024 ! transforming growth factor beta-activated receptor activity + +[Term] +id: GO:0070124 +name: mitochondrial translational initiation +namespace: biological_process +def: "The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA." [GOC:mah] +synonym: "mitochondrial translation initiation" EXACT [GOC:mah] +is_a: GO:0006413 ! translational initiation +intersection_of: GO:0006413 ! translational initiation +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070125 +name: mitochondrial translational elongation +namespace: biological_process +def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." [GOC:mah] +synonym: "mitochondrial translation elongation" EXACT [GOC:mah] +is_a: GO:0006414 ! translational elongation +intersection_of: GO:0006414 ! translational elongation +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070126 +name: mitochondrial translational termination +namespace: biological_process +def: "The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)." [GOC:mah, http://mitogenome.org/index.php/Genetic_Code_of_mitochondria] +synonym: "mitochondrial translation termination" EXACT [GOC:mah] +is_a: GO:0006415 ! translational termination +intersection_of: GO:0006415 ! translational termination +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070127 +name: tRNA aminoacylation for mitochondrial protein translation +namespace: biological_process +def: "The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion." [GOC:mah] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0006418 ! tRNA aminoacylation for protein translation +relationship: part_of GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070129 +name: regulation of mitochondrial translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah] +synonym: "regulation of mitochondrial protein anabolism" EXACT [GOC:mah] +synonym: "regulation of mitochondrial protein biosynthesis" EXACT [GOC:mah] +synonym: "regulation of mitochondrial protein formation" EXACT [GOC:mah] +synonym: "regulation of mitochondrial protein synthesis" EXACT [GOC:mah] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0062125 ! regulation of mitochondrial gene expression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032543 ! mitochondrial translation +relationship: regulates GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070130 +name: negative regulation of mitochondrial translation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah] +synonym: "negative regulation of mitochondrial protein anabolism" EXACT [GOC:mah] +synonym: "negative regulation of mitochondrial protein biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of mitochondrial protein formation" EXACT [GOC:mah] +synonym: "negative regulation of mitochondrial protein synthesis" EXACT [GOC:mah] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:0070129 ! regulation of mitochondrial translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032543 ! mitochondrial translation +relationship: negatively_regulates GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070131 +name: positive regulation of mitochondrial translation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." [GOC:mah] +synonym: "positive regulation of mitochondrial protein anabolism" EXACT [GOC:mah] +synonym: "positive regulation of mitochondrial protein biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of mitochondrial protein formation" EXACT [GOC:mah] +synonym: "positive regulation of mitochondrial protein synthesis" EXACT [GOC:mah] +is_a: GO:0045727 ! positive regulation of translation +is_a: GO:0070129 ! regulation of mitochondrial translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032543 ! mitochondrial translation +relationship: positively_regulates GO:0032543 ! mitochondrial translation + +[Term] +id: GO:0070132 +name: regulation of mitochondrial translational initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah] +synonym: "regulation of mitochondrial translation initiation" EXACT [GOC:mah] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0070129 ! regulation of mitochondrial translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070124 ! mitochondrial translational initiation +relationship: regulates GO:0070124 ! mitochondrial translational initiation + +[Term] +id: GO:0070133 +name: negative regulation of mitochondrial translational initiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah] +synonym: "negative regulation of mitochondrial translation initiation" EXACT [GOC:mah] +is_a: GO:0045947 ! negative regulation of translational initiation +is_a: GO:0070130 ! negative regulation of mitochondrial translation +is_a: GO:0070132 ! regulation of mitochondrial translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070124 ! mitochondrial translational initiation +relationship: negatively_regulates GO:0070124 ! mitochondrial translational initiation + +[Term] +id: GO:0070134 +name: positive regulation of mitochondrial translational initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion." [GOC:mah] +synonym: "positive regulation of mitochondrial translation initiation" EXACT [GOC:mah] +is_a: GO:0045948 ! positive regulation of translational initiation +is_a: GO:0070131 ! positive regulation of mitochondrial translation +is_a: GO:0070132 ! regulation of mitochondrial translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070124 ! mitochondrial translational initiation +relationship: positively_regulates GO:0070124 ! mitochondrial translational initiation + +[Term] +id: GO:0070135 +name: beta-1,2-oligomannoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan." [GOC:mah, PMID:18234669] +synonym: "beta-1,2-oligomannoside metabolism" EXACT [GOC:mah] +is_a: GO:0010412 ! mannan metabolic process + +[Term] +id: GO:0070136 +name: beta-1,2-oligomannoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan." [GOC:mah, PMID:18234669] +synonym: "beta-1,2-oligomannoside anabolism" EXACT [GOC:mah] +synonym: "beta-1,2-oligomannoside biosynthesis" EXACT [GOC:mah] +synonym: "beta-1,2-oligomannoside formation" EXACT [GOC:mah] +synonym: "beta-1,2-oligomannoside synthesis" EXACT [GOC:mah] +is_a: GO:0046354 ! mannan biosynthetic process +is_a: GO:0051278 ! fungal-type cell wall polysaccharide biosynthetic process +is_a: GO:0070135 ! beta-1,2-oligomannoside metabolic process + +[Term] +id: GO:0070137 +name: ubiquitin-like protein-specific endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO)." [GOC:mah] +synonym: "small conjugating protein-specific endopeptidase activity" EXACT [] +is_a: GO:0004197 ! cysteine-type endopeptidase activity +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity + +[Term] +id: GO:0070138 +name: ubiquitin-like protein-specific isopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated." [GOC:mah] +synonym: "small conjugating protein-specific isopeptidase activity" EXACT [GOC:dph] +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity +is_a: GO:0070122 ! isopeptidase activity + +[Term] +id: GO:0070139 +name: SUMO-specific endopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO." [GOC:mah] +xref: Reactome:R-HSA-2990840 "SENP1,2,5 proteolytically process SUMO1" +xref: Reactome:R-HSA-2990842 "SEN1,2,5 proteolytically process SUMO2" +xref: Reactome:R-HSA-2993763 "SENP1,2,5 proteolytically process SUMO3" +is_a: GO:0016929 ! SUMO-specific protease activity +is_a: GO:0070137 ! ubiquitin-like protein-specific endopeptidase activity + +[Term] +id: GO:0070140 +name: SUMO-specific isopeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated." [GOC:mah] +is_a: GO:0016929 ! SUMO-specific protease activity +is_a: GO:0070138 ! ubiquitin-like protein-specific isopeptidase activity + +[Term] +id: GO:0070141 +name: response to UV-A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm." [GOC:BHF, GOC:mah] +synonym: "response to UV-A light stimulus" EXACT [] +synonym: "response to UV-A radiation stimulus" EXACT [] +synonym: "response to UVA light stimulus" EXACT [] +synonym: "response to UVA radiation stimulus" EXACT [] +is_a: GO:0009411 ! response to UV + +[Term] +id: GO:0070142 +name: synaptic vesicle budding +namespace: biological_process +def: "Evagination of a membrane to form a synaptic vesicle." [GOC:mah] +is_a: GO:0006900 ! vesicle budding from membrane +relationship: part_of GO:0048489 ! synaptic vesicle transport + +[Term] +id: GO:0070143 +name: mitochondrial alanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006419 ! alanyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006419 ! alanyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070144 +name: mitochondrial arginyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006420 ! arginyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006420 ! arginyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070145 +name: mitochondrial asparaginyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006421 ! asparaginyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006421 ! asparaginyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070146 +name: mitochondrial aspartyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006422 ! aspartyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006422 ! aspartyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070147 +name: mitochondrial cysteinyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006423 ! cysteinyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006423 ! cysteinyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070148 +name: mitochondrial glutaminyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006425 ! glutaminyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006425 ! glutaminyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070149 +name: mitochondrial glutamyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006424 ! glutamyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006424 ! glutamyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070150 +name: mitochondrial glycyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006426 ! glycyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006426 ! glycyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070151 +name: mitochondrial histidyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006427 ! histidyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006427 ! histidyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070152 +name: mitochondrial isoleucyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006428 ! isoleucyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006428 ! isoleucyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070153 +name: mitochondrial leucyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006429 ! leucyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006429 ! leucyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070154 +name: mitochondrial lysyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006430 ! lysyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006430 ! lysyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070155 +name: mitochondrial methionyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006431 ! methionyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006431 ! methionyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070156 +name: mitochondrial phenylalanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006432 ! phenylalanyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006432 ! phenylalanyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070157 +name: mitochondrial prolyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006433 ! prolyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006433 ! prolyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070158 +name: mitochondrial seryl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006434 ! seryl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006434 ! seryl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070159 +name: mitochondrial threonyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006435 ! threonyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006435 ! threonyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070160 +name: tight junction +namespace: cellular_component +def: "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." [ISBN:0815332181] +synonym: "occluding cell junction" EXACT [GOC:mah] +synonym: "occluding junction" EXACT [GOC:mah] +xref: Wikipedia:Tight_junction +is_a: GO:0005911 ! cell-cell junction + +[Term] +id: GO:0070161 +name: anchoring junction +namespace: cellular_component +def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181] +synonym: "anchoring cell junction" EXACT [GOC:mah] +is_a: GO:0030054 ! cell junction + +[Term] +id: GO:0070162 +name: adiponectin secretion +namespace: biological_process +def: "The regulated release of adiponectin, a protein hormone, by adipose tissue." [GOC:BHF, GOC:rl] +is_a: GO:0009306 ! protein secretion +is_a: GO:0060986 ! endocrine hormone secretion + +[Term] +id: GO:0070163 +name: regulation of adiponectin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:mah] +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070162 ! adiponectin secretion +relationship: regulates GO:0070162 ! adiponectin secretion + +[Term] +id: GO:0070164 +name: negative regulation of adiponectin secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:BHF, GOC:mah] +synonym: "down regulation of adiponectin secretion" EXACT [GOC:mah] +synonym: "down-regulation of adiponectin secretion" EXACT [GOC:mah] +synonym: "downregulation of adiponectin secretion" EXACT [GOC:mah] +synonym: "inhibition of adiponectin secretion" NARROW [GOC:mah] +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0070163 ! regulation of adiponectin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070162 ! adiponectin secretion +relationship: negatively_regulates GO:0070162 ! adiponectin secretion + +[Term] +id: GO:0070165 +name: positive regulation of adiponectin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell." [GOC:BHF, GOC:mah] +synonym: "activation of adiponectin secretion" NARROW [GOC:mah] +synonym: "stimulation of adiponectin secretion" NARROW [GOC:mah] +synonym: "up regulation of adiponectin secretion" EXACT [GOC:mah] +synonym: "up-regulation of adiponectin secretion" EXACT [GOC:mah] +synonym: "upregulation of adiponectin secretion" EXACT [GOC:mah] +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0070163 ! regulation of adiponectin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070162 ! adiponectin secretion +relationship: positively_regulates GO:0070162 ! adiponectin secretion + +[Term] +id: GO:0070166 +name: enamel mineralization +namespace: biological_process +def: "The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel." [GOC:BHF, GOC:mah, GOC:sl, PMID:10206335, PMID:16931858, PMID:21196346] +synonym: "enamel formation" RELATED [PMID:16931858] +is_a: GO:0034505 ! tooth mineralization +relationship: part_of GO:0097186 ! amelogenesis + +[Term] +id: GO:0070167 +name: regulation of biomineral tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah] +is_a: GO:0110149 ! regulation of biomineralization +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031214 ! biomineral tissue development +relationship: regulates GO:0031214 ! biomineral tissue development + +[Term] +id: GO:0070168 +name: negative regulation of biomineral tissue development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0070167 ! regulation of biomineral tissue development +is_a: GO:0110150 ! negative regulation of biomineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031214 ! biomineral tissue development +relationship: negatively_regulates GO:0031214 ! biomineral tissue development + +[Term] +id: GO:0070169 +name: positive regulation of biomineral tissue development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds." [GOC:mah] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0070167 ! regulation of biomineral tissue development +is_a: GO:0110151 ! positive regulation of biomineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031214 ! biomineral tissue development +relationship: positively_regulates GO:0031214 ! biomineral tissue development + +[Term] +id: GO:0070170 +name: regulation of tooth mineralization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah] +is_a: GO:0042481 ! regulation of odontogenesis +is_a: GO:0070167 ! regulation of biomineral tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034505 ! tooth mineralization +relationship: regulates GO:0034505 ! tooth mineralization + +[Term] +id: GO:0070171 +name: negative regulation of tooth mineralization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah] +is_a: GO:0042483 ! negative regulation of odontogenesis +is_a: GO:0070168 ! negative regulation of biomineral tissue development +is_a: GO:0070170 ! regulation of tooth mineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034505 ! tooth mineralization +relationship: negatively_regulates GO:0034505 ! tooth mineralization + +[Term] +id: GO:0070172 +name: positive regulation of tooth mineralization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures." [GOC:BHF, GOC:mah] +is_a: GO:0042482 ! positive regulation of odontogenesis +is_a: GO:0070169 ! positive regulation of biomineral tissue development +is_a: GO:0070170 ! regulation of tooth mineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034505 ! tooth mineralization +relationship: positively_regulates GO:0034505 ! tooth mineralization + +[Term] +id: GO:0070173 +name: regulation of enamel mineralization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah] +is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth +is_a: GO:0070170 ! regulation of tooth mineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070166 ! enamel mineralization +relationship: regulates GO:0070166 ! enamel mineralization + +[Term] +id: GO:0070174 +name: negative regulation of enamel mineralization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah] +is_a: GO:0042489 ! negative regulation of odontogenesis of dentin-containing tooth +is_a: GO:0070171 ! negative regulation of tooth mineralization +is_a: GO:0070173 ! regulation of enamel mineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070166 ! enamel mineralization +relationship: negatively_regulates GO:0070166 ! enamel mineralization + +[Term] +id: GO:0070175 +name: positive regulation of enamel mineralization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel." [GOC:BHF, GOC:mah] +is_a: GO:0042488 ! positive regulation of odontogenesis of dentin-containing tooth +is_a: GO:0070172 ! positive regulation of tooth mineralization +is_a: GO:0070173 ! regulation of enamel mineralization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070166 ! enamel mineralization +relationship: positively_regulates GO:0070166 ! enamel mineralization + +[Term] +id: GO:0070176 +name: DRM complex +namespace: cellular_component +def: "A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification." [PMID:17075059] +synonym: "DP/Rb/MuvB" EXACT [PMID:17075059] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex + +[Term] +id: GO:0070177 +name: contractile vacuole discharge +namespace: biological_process +def: "The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane." [GOC:mah, PMID:10369671] +is_a: GO:0045055 ! regulated exocytosis + +[Term] +id: GO:0070178 +name: D-serine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid." [CHEBI:16523, GOC:jsg, GOC:mah] +synonym: "D-serine metabolism" EXACT [] +is_a: GO:0009069 ! serine family amino acid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process + +[Term] +id: GO:0070179 +name: D-serine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine." [CHEBI:16523, GOC:jsg, GOC:mah] +synonym: "D-serine anabolism" EXACT [] +synonym: "D-serine biosynthesis" EXACT [] +synonym: "D-serine formation" EXACT [] +synonym: "D-serine synthesis" EXACT [] +is_a: GO:0009070 ! serine family amino acid biosynthetic process +is_a: GO:0046437 ! D-amino acid biosynthetic process +is_a: GO:0070178 ! D-serine metabolic process + +[Term] +id: GO:0070180 +name: large ribosomal subunit rRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA." [GOC:elh] +synonym: "25S rRNA binding" EXACT [GOC:elh] +synonym: "LSU rRNA binding" EXACT [] +is_a: GO:0019843 ! rRNA binding + +[Term] +id: GO:0070181 +name: small ribosomal subunit rRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA." [GOC:elh] +synonym: "18S rRNA binding" EXACT [GOC:elh] +synonym: "SSU rRNA binding" EXACT [] +is_a: GO:0019843 ! rRNA binding + +[Term] +id: GO:0070182 +name: DNA polymerase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA polymerase." [GOC:BHF, GOC:mah] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0070183 +name: mitochondrial tryptophanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006436 ! tryptophanyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006436 ! tryptophanyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070184 +name: mitochondrial tyrosyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006437 ! tyrosyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006437 ! tyrosyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070185 +name: mitochondrial valyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA." [GOC:mah, GOC:mcc] +is_a: GO:0006438 ! valyl-tRNA aminoacylation +is_a: GO:0070127 ! tRNA aminoacylation for mitochondrial protein translation +intersection_of: GO:0006438 ! valyl-tRNA aminoacylation +intersection_of: occurs_in GO:0005739 ! mitochondrion + +[Term] +id: GO:0070186 +name: growth hormone activity +namespace: molecular_function +def: "The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth." [GOC:BHF, GOC:mah, PMID:11445442] +synonym: "GH activity" EXACT [PMID:11445442] +synonym: "pituitary growth hormone activity" NARROW [GOC:vk] +synonym: "placental growth hormone activity" NARROW [GOC:vk] +is_a: GO:0005179 ! hormone activity + +[Term] +id: GO:0070187 +name: shelterin complex +namespace: cellular_component +def: "A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1." [GOC:expert_mf, GOC:mah, GOC:vw, PMID:18828880] +synonym: "Pot1 complex" EXACT [GOC:vw] +synonym: "Pot1-Tpz1 complex" EXACT [GOC:vw] +synonym: "telosome" EXACT [GOC:mah, GOC:vw] +is_a: GO:0000783 ! nuclear telomere cap complex + +[Term] +id: GO:0070188 +name: obsolete Stn1-Ten1 complex +namespace: cellular_component +def: "OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present." [GOC:mah, GOC:vw, PMID:17715303, PMID:19064932] +comment: This term was made obsolete because it was inaccurate. +is_obsolete: true +replaced_by: GO:1990879 + +[Term] +id: GO:0070189 +name: kynurenine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine." [CHEBI:28683, GOC:mah, GOC:rph] +synonym: "kynurenine metabolism" EXACT [] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process + +[Term] +id: GO:0070190 +name: obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate." [GOC:jp, PMID:18981179] +comment: This term was made obsolete because it represents two reactions, and should be two separate terms. +synonym: "inositol hexakisphosphate 1-kinase or 3-kinase activity" EXACT [] +is_obsolete: true +consider: GO:0052723 +consider: GO:0052724 + +[Term] +id: GO:0070191 +name: methionine-R-sulfoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin." [GOC:mcc, PMID:17535911, PMID:19049972] +is_a: GO:0016671 ! oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + +[Term] +id: GO:0070192 +name: chromosome organization involved in meiotic cell cycle +namespace: biological_process +def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah] +synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah] +synonym: "meiotic chromosome organization" EXACT [GOC:mah] +is_a: GO:0051276 ! chromosome organization +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051276 ! chromosome organization +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0070193 +name: synaptonemal complex organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis." [GOC:mah] +synonym: "synaptonemal complex organisation" EXACT [GOC:mah] +is_a: GO:0051276 ! chromosome organization +property_value: RO:0002161 NCBITaxon:4896 + +[Term] +id: GO:0070194 +name: synaptonemal complex disassembly +namespace: biological_process +def: "The controlled breakdown of a synaptonemal complex." [GOC:mah] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0070193 ! synaptonemal complex organization + +[Term] +id: GO:0070195 +name: growth hormone receptor complex +namespace: cellular_component +def: "A receptor complex that consists of two identical subunits and binds growth hormone." [GOC:BHF, GOC:mah, GOC:vk, PMID:11445442] +is_a: GO:0043235 ! receptor complex + +[Term] +id: GO:0070196 +name: eukaryotic translation initiation factor 3 complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex." [GOC:mah] +synonym: "eIF-3 assembly" EXACT [GOC:mah] +synonym: "eIF3 assembly" EXACT [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0070197 +name: meiotic attachment of telomere to nuclear envelope +namespace: biological_process +def: "The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation." [GOC:jp, GOC:pr, GOC:vw, PMID:18818742] +synonym: "attachment of telomeres to nuclear envelope" BROAD [] +synonym: "attachment of telomeric chromatin to nuclear envelope" BROAD [] +synonym: "attachment of telomeric heterochromatin to nuclear envelope" EXACT [] +is_a: GO:0097240 ! chromosome attachment to the nuclear envelope +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0044821 ! meiotic telomere tethering at nuclear periphery + +[Term] +id: GO:0070198 +name: protein localization to chromosome, telomeric region +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome." [GOC:BHF, GOC:mah] +synonym: "protein localisation to chromosome, telomeric region" EXACT [GOC:mah] +synonym: "protein localization to telomere" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome + +[Term] +id: GO:0070199 +name: establishment of protein localization to chromosome +namespace: biological_process +def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] +synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome +is_a: GO:0072594 ! establishment of protein localization to organelle + +[Term] +id: GO:0070200 +name: establishment of protein localization to telomere +namespace: biological_process +def: "The directed movement of a protein to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:mah] +synonym: "establishment of protein localisation to telomere" EXACT [GOC:mah] +synonym: "establishment of protein localization to chromosome, telomeric region" EXACT [GOC:mah] +is_a: GO:0070198 ! protein localization to chromosome, telomeric region +is_a: GO:0070199 ! establishment of protein localization to chromosome + +[Term] +id: GO:0070201 +name: regulation of establishment of protein localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah] +synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah] +is_a: GO:0032880 ! regulation of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045184 ! establishment of protein localization +relationship: regulates GO:0045184 ! establishment of protein localization + +[Term] +id: GO:0070202 +name: regulation of establishment of protein localization to chromosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] +synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah] +is_a: GO:0070201 ! regulation of establishment of protein localization +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070199 ! establishment of protein localization to chromosome +relationship: regulates GO:0070199 ! establishment of protein localization to chromosome + +[Term] +id: GO:0070203 +name: regulation of establishment of protein localization to telomere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:mah] +synonym: "regulation of establishment of protein localisation to telomere" EXACT [GOC:mah] +is_a: GO:0070202 ! regulation of establishment of protein localization to chromosome +is_a: GO:1904814 ! regulation of protein localization to chromosome, telomeric region +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070200 ! establishment of protein localization to telomere +relationship: regulates GO:0070200 ! establishment of protein localization to telomere + +[Term] +id: GO:0070204 +name: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2)." [EC:2.2.1.9, RHEA:25593] +comment: Note that this function was formerly EC:4.1.3.18. +synonym: "MenD" RELATED [EC:2.2.1.9] +synonym: "SEPHCHC synthase activity" EXACT [EC:2.2.1.9] +xref: EC:2.2.1.9 +xref: KEGG_REACTION:R08165 +xref: MetaCyc:2.5.1.64-RXN +xref: RHEA:25593 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0070205 +name: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate." [EC:4.2.99.20, RHEA:25597] +synonym: "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity" EXACT [EC:4.2.99.20] +synonym: "6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity" EXACT [EC:4.2.99.20] +synonym: "MenH" RELATED [EC:4.2.99.20] +synonym: "SHCHC synthase activity" EXACT [EC:4.2.99.20] +synonym: "YfbB" RELATED [EC:4.2.99.20] +xref: EC:4.2.99.20 +xref: KEGG_REACTION:R08166 +xref: MetaCyc:RXN-9310 +xref: RHEA:25597 +is_a: GO:0016835 ! carbon-oxygen lyase activity + +[Term] +id: GO:0070206 +name: protein trimerization +namespace: biological_process +def: "The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits." [GOC:hjd] +synonym: "protein trimer assembly" EXACT [GOC:hjd] +synonym: "protein trimer biosynthesis" EXACT [GOC:hjd] +synonym: "protein trimer biosynthetic process" EXACT [GOC:hjd] +synonym: "protein trimer formation" EXACT [GOC:hjd] +is_a: GO:0051259 ! protein complex oligomerization + +[Term] +id: GO:0070207 +name: protein homotrimerization +namespace: biological_process +def: "The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits." [GOC:hjd] +synonym: "protein homotrimer assembly" EXACT [GOC:hjd] +synonym: "protein homotrimer biosynthesis" EXACT [GOC:hjd] +synonym: "protein homotrimer biosynthetic process" EXACT [GOC:hjd] +synonym: "protein homotrimer formation" EXACT [GOC:hjd] +is_a: GO:0051260 ! protein homooligomerization +is_a: GO:0070206 ! protein trimerization + +[Term] +id: GO:0070208 +name: protein heterotrimerization +namespace: biological_process +def: "The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical." [GOC:hjd] +synonym: "protein heterotrimer assembly" EXACT [GOC:hjd] +synonym: "protein heterotrimer biosynthesis" EXACT [GOC:hjd] +synonym: "protein heterotrimer biosynthetic process" EXACT [GOC:hjd] +synonym: "protein heterotrimer formation" EXACT [GOC:hjd] +is_a: GO:0051291 ! protein heterooligomerization +is_a: GO:0070206 ! protein trimerization + +[Term] +id: GO:0070209 +name: ASTRA complex +namespace: cellular_component +def: "A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p." [GOC:rb, PMID:19040720, PMID:22505622] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:0110078 ! TTT complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0070210 +name: Rpd3L-Expanded complex +namespace: cellular_component +def: "A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins." [GOC:rb, PMID:19040720] +synonym: "Clr6-LE complex" EXACT [GOC:vw] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0070211 +name: Snt2C complex +namespace: cellular_component +def: "A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p." [GOC:rb, PMID:19040720] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin + +[Term] +id: GO:0070212 +name: protein poly-ADP-ribosylation +namespace: biological_process +def: "The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain." [GOC:BHF, GOC:mah, GOC:rl, PMID:25043379] +synonym: "addition of poly-ADP-ribose to protein" EXACT [GOC:rl] +synonym: "poly(ADP-ribose) addition to protein" EXACT [GOC:rl] +synonym: "protein amino acid poly-ADP-ribosylation" EXACT [GOC:bf] +synonym: "protein poly(ADP-ribose) metabolism" RELATED [GOC:rl] +synonym: "protein poly(ADP-ribose) synthesis" EXACT [GOC:rl] +is_a: GO:0006471 ! protein ADP-ribosylation + +[Term] +id: GO:0070213 +name: protein auto-ADP-ribosylation +namespace: biological_process +def: "The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [GOC:BHF, GOC:rl] +synonym: "protein amino acid auto-ADP-ribosylation" EXACT [GOC:bf] +is_a: GO:0006471 ! protein ADP-ribosylation + +[Term] +id: GO:0070214 +name: CSK-GAP-A.p62 complex +namespace: cellular_component +def: "A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation." [PMID:7544435] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0031252 ! cell leading edge + +[Term] +id: GO:0070215 +name: obsolete MDM2 binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM2 protein, a negative regulator of p53." [GOC:mah, GOC:nln] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "MDM2 binding" EXACT [] +is_obsolete: true +replaced_by: GO:0097371 + +[Term] +id: GO:0070216 +name: obsolete MDM4 binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM4 protein, a negative regulator of p53." [GOC:mah, GOC:nln] +comment: This term was made obsolete because it represents binding to an individual protein. +synonym: "MDM4 binding" EXACT [] +synonym: "MDMX binding" EXACT [GOC:nln] +is_obsolete: true +replaced_by: GO:0097371 + +[Term] +id: GO:0070217 +name: transcription factor TFIIIB complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex." [GOC:mah] +synonym: "TFIIIB assembly" EXACT [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly + +[Term] +id: GO:0070218 +name: sulfide ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell." [GOC:mah] +synonym: "sulfide generation" RELATED [GOC:mah] +synonym: "sulfide homeostasis" EXACT [GOC:mah] +synonym: "sulfide production" RELATED [GOC:mah] +synonym: "sulphide generation" RELATED [GOC:mah] +synonym: "sulphide homeostasis" EXACT [GOC:mah] +synonym: "sulphide ion homeostasis" EXACT [GOC:mah] +synonym: "sulphide production" RELATED [GOC:mah] +is_a: GO:0055083 ! monovalent inorganic anion homeostasis +is_a: GO:0072505 ! divalent inorganic anion homeostasis + +[Term] +id: GO:0070219 +name: cellular sulfide ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell." [GOC:mah] +synonym: "cellular sulfide homeostasis" EXACT [GOC:mah] +synonym: "cellular sulphide homeostasis" EXACT [GOC:mah] +synonym: "cellular sulphide ion homeostasis" EXACT [GOC:mah] +is_a: GO:0030320 ! cellular monovalent inorganic anion homeostasis +is_a: GO:0070218 ! sulfide ion homeostasis +is_a: GO:0072501 ! cellular divalent inorganic anion homeostasis + +[Term] +id: GO:0070220 +name: aerobic sulfur oxidation +namespace: biological_process +def: "A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen." [MetaCyc:SULFUROX-PWY] +synonym: "aerobic sulphur oxidation" EXACT [GOC:mah] +xref: MetaCyc:SULFUROX-PWY +is_a: GO:0019417 ! sulfur oxidation + +[Term] +id: GO:0070221 +name: sulfide oxidation, using sulfide:quinone oxidoreductase +namespace: biological_process +def: "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase." [MetaCyc:P222-PWY] +synonym: "sulfide oxidation, using sulfide-quinone reductase" EXACT [GOC:mah, MetaCyc:P222-PWY] +synonym: "sulphide oxidation, using sulfide:quinone oxidoreductase" EXACT [GOC:mah] +xref: MetaCyc:P222-PWY +is_a: GO:0019418 ! sulfide oxidation + +[Term] +id: GO:0070222 +name: sulfide oxidation, using sulfide dehydrogenase +namespace: biological_process +def: "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase." [MetaCyc:PWY-5274] +synonym: "sulphide oxidation, using sulfide dehydrogenase" EXACT [GOC:mah] +xref: MetaCyc:PWY-5274 +is_a: GO:0019418 ! sulfide oxidation + +[Term] +id: GO:0070223 +name: sulfide oxidation, using sulfur dioxygenase +namespace: biological_process +def: "A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase." [MetaCyc:PWY-5285] +synonym: "sulphide oxidation, using sulfur dioxygenase" EXACT [GOC:mah] +xref: MetaCyc:PWY-5285 +is_a: GO:0019418 ! sulfide oxidation + +[Term] +id: GO:0070224 +name: sulfide:quinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone." [MetaCyc:R17-RXN] +synonym: "sulfide-quinone reductase activity" EXACT [MetaCyc:MONOMER-12314] +synonym: "sulphide:quinone oxidoreductase activity" EXACT [GOC:mah] +xref: MetaCyc:R17-RXN +xref: Reactome:R-HSA-1614665 "SQR oxidizes sulfide to bound persulfide" +is_a: GO:0016672 ! oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0070225 +name: sulfide dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c." [MetaCyc:RXN-8156] +synonym: "flavocytochrome c sulfide dehydrogenase activity" EXACT [MetaCyc:RXN-8156] +synonym: "sulphide dehydrogenase activity" EXACT [GOC:mah] +xref: EC:1.8.2 +xref: MetaCyc:RXN-8156 +is_a: GO:0016669 ! oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor + +[Term] +id: GO:0070226 +name: sulfur:ferric ion oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+." [MetaCyc:SULFFEOXIDO-RXN] +synonym: "hydrogen sulfide:ferric ion oxidoreductase" EXACT [MetaCyc:SULFFEOXIDO-RXN] +xref: MetaCyc:SULFFEOXIDO-RXN +is_a: GO:0016667 ! oxidoreductase activity, acting on a sulfur group of donors + +[Term] +id: GO:0070227 +name: lymphocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "lymphocyte apoptosis" NARROW [] +is_a: GO:0071887 ! leukocyte apoptotic process + +[Term] +id: GO:0070228 +name: regulation of lymphocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "regulation of lymphocyte apoptosis" NARROW [] +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070227 ! lymphocyte apoptotic process +relationship: regulates GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0070229 +name: negative regulation of lymphocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add] +synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add] +synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add] +synonym: "inhibition of lymphocyte apoptosis" NARROW [GOC:add] +synonym: "negative regulation of lymphocyte apoptosis" NARROW [] +is_a: GO:0070228 ! regulation of lymphocyte apoptotic process +is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070227 ! lymphocyte apoptotic process +relationship: negatively_regulates GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0070230 +name: positive regulation of lymphocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "activation of lymphocyte apoptosis" NARROW [GOC:add] +synonym: "positive regulation of lymphocyte apoptosis" NARROW [] +synonym: "stimulation of lymphocyte apoptosis" NARROW [GOC:add] +synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add] +synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add] +synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add] +is_a: GO:0070228 ! regulation of lymphocyte apoptotic process +is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070227 ! lymphocyte apoptotic process +relationship: positively_regulates GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0070231 +name: T cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add] +synonym: "T cell apoptosis" NARROW [] +synonym: "T lymphocyte apoptosis" EXACT [GOC:add] +synonym: "T-cell apoptosis" EXACT [GOC:add] +synonym: "T-lymphocyte apoptosis" EXACT [GOC:add] +is_a: GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0070232 +name: regulation of T cell apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] +synonym: "regulation of T cell apoptosis" NARROW [] +synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add] +synonym: "regulation of T-cell apoptosis" EXACT [GOC:add] +synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add] +is_a: GO:0070228 ! regulation of lymphocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070231 ! T cell apoptotic process +relationship: regulates GO:0070231 ! T cell apoptotic process + +[Term] +id: GO:0070233 +name: negative regulation of T cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "down regulation of T cell apoptosis" EXACT [GOC:add] +synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add] +synonym: "downregulation of T cell apoptosis" EXACT [GOC:add] +synonym: "inhibition of T cell apoptosis" NARROW [GOC:add] +synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] +synonym: "negative regulation of T cell apoptosis" NARROW [] +synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add] +synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add] +synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add] +is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070231 ! T cell apoptotic process +relationship: negatively_regulates GO:0070231 ! T cell apoptotic process + +[Term] +id: GO:0070234 +name: positive regulation of T cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "activation of T cell apoptosis" NARROW [GOC:add] +synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] +synonym: "positive regulation of T cell apoptosis" NARROW [] +synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add] +synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add] +synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add] +synonym: "stimulation of T cell apoptosis" NARROW [GOC:add] +synonym: "up regulation of T cell apoptosis" EXACT [GOC:add] +synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add] +synonym: "upregulation of T cell apoptosis" EXACT [GOC:add] +is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070231 ! T cell apoptotic process +relationship: positively_regulates GO:0070231 ! T cell apoptotic process + +[Term] +id: GO:0070235 +name: regulation of activation-induced cell death of T cells +namespace: biological_process +def: "Any process that modulates the occurrence or rate of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196] +synonym: "regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "regulation of activation-induced cell death of T lymphocytes" EXACT [GOC:add] +synonym: "regulation of activation-induced cell death of T-cells" EXACT [GOC:add] +synonym: "regulation of activation-induced cell death of T-lymphocytes" EXACT [GOC:add] +synonym: "regulation of AICD" BROAD [GOC:add] +synonym: "regulation of antigen-driven apoptosis" BROAD [GOC:add] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006924 ! activation-induced cell death of T cells +relationship: regulates GO:0006924 ! activation-induced cell death of T cells + +[Term] +id: GO:0070236 +name: negative regulation of activation-induced cell death of T cells +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196] +synonym: "down regulation of activation-induced cell death of T cells" EXACT [GOC:add] +synonym: "down-regulation of activation-induced cell death of T cells" EXACT [GOC:add] +synonym: "downregulation of activation-induced cell death of T cells" EXACT [GOC:add] +synonym: "inhibition of activation-induced cell death of T cells" NARROW [GOC:add] +synonym: "negative regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "negative regulation of activation-induced cell death of T lymphocytes" EXACT [GOC:add] +synonym: "negative regulation of activation-induced cell death of T-cells" EXACT [GOC:add] +synonym: "negative regulation of activation-induced cell death of T-lymphocytes" EXACT [GOC:add] +synonym: "negative regulation of AICD" BROAD [GOC:add] +synonym: "negative regulation of antigen-driven apoptosis" BROAD [] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0070233 ! negative regulation of T cell apoptotic process +is_a: GO:0070235 ! regulation of activation-induced cell death of T cells +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006924 ! activation-induced cell death of T cells +relationship: negatively_regulates GO:0006924 ! activation-induced cell death of T cells + +[Term] +id: GO:0070237 +name: positive regulation of activation-induced cell death of T cells +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells." [GOC:add, ISBN:0781765196] +synonym: "activation of activation-induced cell death of T cells" NARROW [GOC:add] +synonym: "positive regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "positive regulation of activation-induced cell death of T lymphocytes" EXACT [GOC:add] +synonym: "positive regulation of activation-induced cell death of T-cells" EXACT [GOC:add] +synonym: "positive regulation of activation-induced cell death of T-lymphocytes" EXACT [GOC:add] +synonym: "positive regulation of AICD" BROAD [GOC:add] +synonym: "positive regulation of antigen-driven apoptosis" BROAD [GOC:add] +synonym: "stimulation of activation-induced cell death of T cells" NARROW [GOC:add] +synonym: "up regulation of activation-induced cell death of T cells" EXACT [GOC:add] +synonym: "up-regulation of activation-induced cell death of T cells" EXACT [GOC:add] +synonym: "upregulation of activation-induced cell death of T cells" EXACT [GOC:add] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0070234 ! positive regulation of T cell apoptotic process +is_a: GO:0070235 ! regulation of activation-induced cell death of T cells +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006924 ! activation-induced cell death of T cells +relationship: positively_regulates GO:0006924 ! activation-induced cell death of T cells + +[Term] +id: GO:0070238 +name: activated T cell autonomous cell death +namespace: biological_process +def: "A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "ACAD" BROAD [GOC:add] +synonym: "activated cell autonomous cell death" BROAD [GOC:add] +synonym: "activated T cell apoptosis" BROAD [GOC:add] +synonym: "activated T lymphocyte autonomous cell death" EXACT [GOC:add] +synonym: "activated T-cell autonomous cell death" EXACT [GOC:add] +synonym: "activated T-lymphocyte autonomous cell death" EXACT [GOC:add] +is_a: GO:0070231 ! T cell apoptotic process +relationship: part_of GO:0043029 ! T cell homeostasis + +[Term] +id: GO:0070239 +name: regulation of activated T cell autonomous cell death +namespace: biological_process +def: "Any process that modulates the occurrence or rate of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "regulation of ACAD" BROAD [GOC:add] +synonym: "regulation of activated cell autonomous cell death" BROAD [GOC:add] +synonym: "regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "regulation of activated T lymphocyte autonomous cell death" EXACT [GOC:add] +synonym: "regulation of activated T-cell autonomous cell death" EXACT [GOC:add] +synonym: "regulation of activated T-lymphocyte autonomous cell death" EXACT [GOC:add] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070238 ! activated T cell autonomous cell death +relationship: regulates GO:0070238 ! activated T cell autonomous cell death + +[Term] +id: GO:0070240 +name: negative regulation of activated T cell autonomous cell death +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "down regulation of activated T cell autonomous cell death" EXACT [GOC:add] +synonym: "down-regulation of activated T cell autonomous cell death" EXACT [GOC:add] +synonym: "downregulation of activated T cell autonomous cell death" EXACT [GOC:add] +synonym: "inhibition of activated T cell autonomous cell death" NARROW [GOC:add] +synonym: "negative regulation of ACAD" BROAD [GOC:add] +synonym: "negative regulation of activated cell autonomous cell death" BROAD [GOC:add] +synonym: "negative regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "negative regulation of activated T lymphocyte autonomous cell death" EXACT [GOC:add] +synonym: "negative regulation of activated T-cell autonomous cell death" EXACT [GOC:add] +synonym: "negative regulation of activated T-lymphocyte autonomous cell death" EXACT [GOC:add] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0070233 ! negative regulation of T cell apoptotic process +is_a: GO:0070239 ! regulation of activated T cell autonomous cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070238 ! activated T cell autonomous cell death +relationship: negatively_regulates GO:0070238 ! activated T cell autonomous cell death + +[Term] +id: GO:0070241 +name: positive regulation of activated T cell autonomous cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "activation of activated T cell autonomous cell death" NARROW [GOC:add] +synonym: "positive regulation of ACAD" BROAD [GOC:add] +synonym: "positive regulation of activated cell autonomous cell death" BROAD [GOC:add] +synonym: "positive regulation of activated T cell apoptosis" BROAD [GOC:add] +synonym: "positive regulation of activated T lymphocyte autonomous cell death" EXACT [GOC:add] +synonym: "positive regulation of activated T-cell autonomous cell death" EXACT [GOC:add] +synonym: "positive regulation of activated T-lymphocyte autonomous cell death" EXACT [GOC:add] +synonym: "stimulation of activated T cell autonomous cell death" NARROW [GOC:add] +synonym: "up regulation of activated T cell autonomous cell death" EXACT [GOC:add] +synonym: "up-regulation of activated T cell autonomous cell death" EXACT [GOC:add] +synonym: "upregulation of activated T cell autonomous cell death" EXACT [GOC:add] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0070234 ! positive regulation of T cell apoptotic process +is_a: GO:0070239 ! regulation of activated T cell autonomous cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070238 ! activated T cell autonomous cell death +relationship: positively_regulates GO:0070238 ! activated T cell autonomous cell death + +[Term] +id: GO:0070242 +name: thymocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a thymocyte, an immature T cell located in the thymus." [CL:0000893, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a thymocyte is an immature T cell located in the thymus (CL:0000893). +synonym: "immature T cell apoptosis" RELATED [GOC:add] +synonym: "thymocyte apoptosis" NARROW [] +is_a: GO:0070231 ! T cell apoptotic process + +[Term] +id: GO:0070243 +name: regulation of thymocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a thymocyte is an immature T cell located in the thymus (CL:0000893). +synonym: "regulation of immature T cell apoptosis" RELATED [GOC:add] +synonym: "regulation of thymocyte apoptosis" NARROW [] +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070242 ! thymocyte apoptotic process +relationship: regulates GO:0070242 ! thymocyte apoptotic process + +[Term] +id: GO:0070244 +name: negative regulation of thymocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a thymocyte is an immature T cell located in the thymus (CL:0000893). +synonym: "down regulation of thymocyte apoptosis" EXACT [GOC:add] +synonym: "down-regulation of thymocyte apoptosis" EXACT [GOC:add] +synonym: "downregulation of thymocyte apoptosis" EXACT [GOC:add] +synonym: "inhibition of thymocyte apoptosis" NARROW [GOC:add] +synonym: "negative regulation of immature T cell apoptosis" RELATED [GOC:add] +synonym: "negative regulation of thymocyte apoptosis" NARROW [] +is_a: GO:0070233 ! negative regulation of T cell apoptotic process +is_a: GO:0070243 ! regulation of thymocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070242 ! thymocyte apoptotic process +relationship: negatively_regulates GO:0070242 ! thymocyte apoptotic process + +[Term] +id: GO:0070245 +name: positive regulation of thymocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +comment: Note that a thymocyte is an immature T cell located in the thymus (CL:0000893). +synonym: "activation of thymocyte apoptosis" NARROW [GOC:add] +synonym: "positive regulation of immature T cell apoptosis" RELATED [GOC:add] +synonym: "positive regulation of thymocyte apoptosis" NARROW [] +synonym: "stimulation of thymocyte apoptosis" NARROW [GOC:add] +synonym: "up regulation of thymocyte apoptosis" EXACT [GOC:add] +synonym: "up-regulation of thymocyte apoptosis" EXACT [GOC:add] +synonym: "upregulation of thymocyte apoptosis" EXACT [GOC:add] +is_a: GO:0070234 ! positive regulation of T cell apoptotic process +is_a: GO:0070243 ! regulation of thymocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070242 ! thymocyte apoptotic process +relationship: positively_regulates GO:0070242 ! thymocyte apoptotic process + +[Term] +id: GO:0070246 +name: natural killer cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation." [CL:0000623, GOC:add, GOC:mtg_apoptosis, PMID:15728472] +synonym: "natural killer cell apoptosis" NARROW [] +synonym: "NK cell apoptosis" EXACT [GOC:add] +is_a: GO:0070227 ! lymphocyte apoptotic process + +[Term] +id: GO:0070247 +name: regulation of natural killer cell apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "regulation of natural killer cell apoptosis" NARROW [] +synonym: "regulation of NK cell apoptosis" EXACT [GOC:add] +is_a: GO:0070228 ! regulation of lymphocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070246 ! natural killer cell apoptotic process +relationship: regulates GO:0070246 ! natural killer cell apoptotic process + +[Term] +id: GO:0070248 +name: negative regulation of natural killer cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "down regulation of natural killer cell apoptosis" EXACT [GOC:add] +synonym: "down-regulation of natural killer cell apoptosis" EXACT [GOC:add] +synonym: "downregulation of natural killer cell apoptosis" EXACT [GOC:add] +synonym: "inhibition of natural killer cell apoptosis" NARROW [GOC:add] +synonym: "negative regulation of natural killer cell apoptosis" NARROW [] +synonym: "negative regulation of NK cell apoptosis" EXACT [GOC:add] +is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process +is_a: GO:0070247 ! regulation of natural killer cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070246 ! natural killer cell apoptotic process +relationship: negatively_regulates GO:0070246 ! natural killer cell apoptotic process + +[Term] +id: GO:0070249 +name: positive regulation of natural killer cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] +synonym: "activation of natural killer cell apoptosis" NARROW [GOC:add] +synonym: "positive regulation of natural killer cell apoptosis" NARROW [] +synonym: "positive regulation of NK cell apoptosis" EXACT [GOC:add] +synonym: "stimulation of natural killer cell apoptosis" NARROW [GOC:add] +synonym: "up regulation of natural killer cell apoptosis" EXACT [GOC:add] +synonym: "up-regulation of natural killer cell apoptosis" EXACT [GOC:add] +synonym: "upregulation of natural killer cell apoptosis" EXACT [GOC:add] +is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process +is_a: GO:0070247 ! regulation of natural killer cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070246 ! natural killer cell apoptotic process +relationship: positively_regulates GO:0070246 ! natural killer cell apoptotic process + +[Term] +id: GO:0070250 +name: mating projection membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone." [GOC:jp] +synonym: "shmoo membrane" NARROW [GOC:jp] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0005937 ! mating projection + +[Term] +id: GO:0070251 +name: pristanate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA." [GOC:pde, PMID:10198260] +synonym: "pristanate:CoA ligase (AMP-forming)" EXACT [GOC:mah] +synonym: "pristanoyl-CoA ligase activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-389632 "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate" +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0070252 +name: actin-mediated cell contraction +namespace: biological_process +def: "The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body." [GOC:mah] +is_a: GO:0030048 ! actin filament-based movement + +[Term] +id: GO:0070253 +name: somatostatin secretion +namespace: biological_process +def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0070254 +name: mucus secretion +namespace: biological_process +def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544] +synonym: "mucus production" EXACT [GOC:add] +is_a: GO:0007589 ! body fluid secretion +is_a: GO:0032941 ! secretion by tissue +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901264 ! carbohydrate derivative transport + +[Term] +id: GO:0070255 +name: regulation of mucus secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] +synonym: "regulation of mucus production" EXACT [GOC:add] +is_a: GO:0050878 ! regulation of body fluid levels +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070254 ! mucus secretion +relationship: regulates GO:0070254 ! mucus secretion + +[Term] +id: GO:0070256 +name: negative regulation of mucus secretion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] +synonym: "negative regulation of mucus production" EXACT [GOC:add] +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0070255 ! regulation of mucus secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070254 ! mucus secretion +relationship: negatively_regulates GO:0070254 ! mucus secretion + +[Term] +id: GO:0070257 +name: positive regulation of mucus secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] +synonym: "positive regulation of mucus production" EXACT [GOC:add] +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0070255 ! regulation of mucus secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070254 ! mucus secretion +relationship: positively_regulates GO:0070254 ! mucus secretion + +[Term] +id: GO:0070258 +name: inner membrane pellicle complex +namespace: cellular_component +def: "A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell." [GOC:mah, PMID:12456714] +synonym: "inner membrane complex" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020039 ! pellicle + +[Term] +id: GO:0070259 +name: tyrosyl-DNA phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA." [GOC:elh, PMID:16751265] +comment: See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'. +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA + +[Term] +id: GO:0070260 +name: 5'-tyrosyl-DNA phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA." [PMID:16751265] +comment: See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'. +is_a: GO:0070259 ! tyrosyl-DNA phosphodiesterase activity + +[Term] +id: GO:0070262 +name: peptidyl-serine dephosphorylation +namespace: biological_process +def: "The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine." [GOC:bf] +is_a: GO:0006470 ! protein dephosphorylation + +[Term] +id: GO:0070263 +name: external side of fungal-type cell wall +namespace: cellular_component +def: "The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents." [GOC:mah] +is_a: GO:0010339 ! external side of cell wall +relationship: part_of GO:0009277 ! fungal-type cell wall + +[Term] +id: GO:0070264 +name: transcription factor TFIIIE complex +namespace: cellular_component +def: "A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins." [GOC:jp, PMID:19116144] +is_a: GO:0090576 ! RNA polymerase III transcription regulator complex + +[Term] +id: GO:0070265 +name: necrotic cell death +namespace: biological_process +def: "A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." [GOC:mtg_apoptosis, PMID:18846107, PMID:20823910] +comment: Note that the word necrosis has been widely used in earlier literature to describe forms of cell death which are now known by more precise terms, such as apoptosis. Necrosis can occur in a regulated fashion, involving a precise sequence of signals; in this case, consider annotating to GO:0097300 'programmed necrotic cell death' or to its more specific child GO:0070266 'necroptotic process'. +synonym: "cellular necrosis" EXACT [GOC:add] +synonym: "necrosis" BROAD [GOC:mah] +is_a: GO:0008219 ! cell death + +[Term] +id: GO:0070266 +name: necroptotic process +namespace: biological_process +alt_id: GO:0060553 +alt_id: GO:0060554 +alt_id: GO:0060555 +def: "A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former." [GOC:BHF, GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, PMID:18846107, PMID:20823910, PMID:21737330, PMID:21760595, PMID:21876153] +comment: Examples of this are Birc2 and Birc3 (UniProt symbols Q62210 and O08863) in PMID:21052097. +synonym: "activation of necroptosis" RELATED [] +synonym: "activation of necroptosis by extracellular signals" RELATED [] +synonym: "activation of necroptosis in response to extracellular signals" RELATED [] +synonym: "activation of necroptosis of activated-T cells" RELATED [] +synonym: "establishment of necroptosis" RELATED [] +synonym: "establishment of necroptosis of activated-T cells" RELATED [] +synonym: "extracellular signal-induced necroptosis" RELATED [] +synonym: "induction of necroptosis" BROAD [] +synonym: "induction of necroptosis by extracellular signals" BROAD [] +synonym: "induction of necroptosis of activated-T cells" BROAD [] +synonym: "necroptosis" NARROW [] +synonym: "PARP-dependent cell death" RELATED [] +synonym: "parthanatos" RELATED [] +synonym: "programmed necrosis" BROAD [Reactome:R-HSA-5213460.1] +synonym: "programmed necrotic cell death" BROAD [GOC:mah] +synonym: "RIPK1-mediated regulated necrosis" EXACT [Reactome:R-HSA-5213460.1] +synonym: "TNF-induced necroptosis" NARROW [PMID:21876153] +is_a: GO:0097300 ! programmed necrotic cell death + +[Term] +id: GO:0070267 +name: oncosis +namespace: biological_process +def: "A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death." [PMID:17873035, PMID:18846107] +comment: Note that oncosis is sometimes described as a type of cell death, but recent nomenclature recommendations define it as a feature of necrotic cell death rather than a distinct mode of cell death. +is_a: GO:0045793 ! positive regulation of cell size +relationship: part_of GO:0070265 ! necrotic cell death + +[Term] +id: GO:0070268 +name: cornification +namespace: biological_process +def: "A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability)." [GOC:krc, PMID:18846107] +is_a: GO:0012501 ! programmed cell death +relationship: has_part GO:1903575 ! cornified envelope assembly +relationship: part_of GO:0031424 ! keratinization + +[Term] +id: GO:0070269 +name: pyroptosis +namespace: biological_process +def: "A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18." [GOC:mtg_apoptosis, PMID:18846107, PMID:21760595] +is_a: GO:0012501 ! programmed cell death + +[Term] +id: GO:0070270 +name: obsolete mitotic catastrophe +namespace: biological_process +def: "OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation." [PMID:18846107] +comment: This term was made obsolete because it does not refer to a true process, but rather to the consequences of aberrations occurred during mitosis. +synonym: "cell death occurring during metaphase" RELATED [PMID:18846107] +synonym: "cell death preceded by multinucleation" RELATED [PMID:18846107] +synonym: "mitotic catastrophe" EXACT [] +is_obsolete: true + +[Term] +id: GO:0070271 +name: obsolete protein complex biogenesis +namespace: biological_process +def: "OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex." [GOC:mah] +synonym: "protein complex biogenesis and assembly" EXACT [GOC:mah] +is_obsolete: true + +[Term] +id: GO:0070272 +name: obsolete proton-transporting ATP synthase complex biogenesis +namespace: biological_process +def: "OBSOLETE. The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:mah, PMID:19103153] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +synonym: "F-type ATPase complex biogenesis" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0070273 +name: phosphatidylinositol-4-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position." [GOC:bf, GOC:mah] +is_a: GO:1901981 ! phosphatidylinositol phosphate binding + +[Term] +id: GO:0070274 +name: RES complex +namespace: cellular_component +def: "A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p." [PMID:15565172, PMID:18809678, PMID:19010333, PMID:19033360] +synonym: "pre-mRNA retention and splicing complex" EXACT [GOC:sre] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070275 +name: aerobic ammonia oxidation to nitrite via pyruvic oxime +namespace: biological_process +def: "The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite." [MetaCyc:PWY-2242] +xref: MetaCyc:PWY-2242 +is_a: GO:0019329 ! ammonia oxidation + +[Term] +id: GO:0070276 +name: halogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds." [CHEBI:22473, GOC:mah] +synonym: "halogen metabolism" EXACT [] +is_a: GO:0044281 ! small molecule metabolic process + +[Term] +id: GO:0070277 +name: iodide oxidation +namespace: biological_process +def: "The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons." [GOC:mah, MetaCyc:IODIDE-PEROXIDASE-RXN] +is_a: GO:0055114 ! oxidation-reduction process +is_a: GO:0070276 ! halogen metabolic process + +[Term] +id: GO:0070278 +name: extracellular matrix constituent secretion +namespace: biological_process +def: "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell." [GOC:mah] +synonym: "ECM constituent secretion" EXACT [GOC:mah] +synonym: "ECM secretion" EXACT [GOC:mah] +is_a: GO:0032940 ! secretion by cell +relationship: part_of GO:0030198 ! extracellular matrix organization + +[Term] +id: GO:0070279 +name: vitamin B6 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:mah] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding + +[Term] +id: GO:0070280 +name: pyridoxal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6." [CHEBI:17310, GOC:mah] +is_a: GO:0043169 ! cation binding +is_a: GO:0048037 ! cofactor binding +is_a: GO:0070279 ! vitamin B6 binding + +[Term] +id: GO:0070281 +name: pyridoxamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6." [CHEBI:16410, GOC:mah] +is_a: GO:0043169 ! cation binding +is_a: GO:0070279 ! vitamin B6 binding + +[Term] +id: GO:0070282 +name: pyridoxine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6." [CHEBI:16709, GOC:mah] +is_a: GO:0048037 ! cofactor binding +is_a: GO:0070279 ! vitamin B6 binding + +[Term] +id: GO:0070284 +name: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine." [PMID:18953358] +synonym: "HMP-P synthase activity" EXACT [PMID:18953358] +synonym: "ThiC" RELATED [PMID:18953358] +is_a: GO:0016853 ! isomerase activity + +[Term] +id: GO:0070285 +name: pigment cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0050931 ! pigment cell differentiation + +[Term] +id: GO:0070286 +name: axonemal dynein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion." [GOC:cilia, GOC:mah, PMID:19052621] +synonym: "dynein arm assembly" EXACT [GOC:vk, PMID:19944405] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0035082 ! axoneme assembly + +[Term] +id: GO:0070287 +name: ferritin receptor activity +namespace: molecular_function +def: "Combining with ferritin, and delivering ferritin into the cell via endocytosis." [GOC:bf, PMID:17459943, PMID:19154717] +synonym: "ferritin complex receptor activity" EXACT [GOC:mah] +is_a: GO:0038024 ! cargo receptor activity + +[Term] +id: GO:0070288 +name: ferritin complex +namespace: cellular_component +def: "A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain." [GOC:mah, PMID:19154717] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0070289 +name: extracellular ferritin complex +namespace: cellular_component +def: "A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains." [GOC:mah, PMID:19154717] +synonym: "serum ferritin complex" RELATED [PMID:19154717] +is_a: GO:0070288 ! ferritin complex +relationship: part_of GO:0005576 ! extracellular region + +[Term] +id: GO:0070290 +name: N-acylphosphatidylethanolamine-specific phospholipase D activity +namespace: molecular_function +def: "Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE)." [GOC:elh, PMID:14634025, PMID:15878693] +subset: goslim_chembl +synonym: "N-acyl-phosphatidylethanolamine-specific phospholipase D activity" EXACT [] +synonym: "NAPE-specific phospholipase D activity" EXACT [] +xref: EC:3.1.4.4 +xref: Reactome:R-HSA-2466831 "A2PE hydrolyses to A2E" +is_a: GO:0004620 ! phospholipase activity +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0070291 +name: N-acylethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group." [CHEBI:52640, GOC:elh, PMID:14634025, PMID:15878693] +synonym: "N-acylethanolamine metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +synonym: "NAE metabolic process" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +synonym: "NAE metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042439 ! ethanolamine-containing compound metabolic process + +[Term] +id: GO:0070292 +name: N-acylphosphatidylethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group." [GOC:elh, GOC:mah, PMID:14634025, PMID:15878693] +synonym: "N-acylphosphatidylethanolamine metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +synonym: "NAPE metabolic process" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +synonym: "NAPE metabolism" EXACT [GOC:elh, PMID:14634025, PMID:15877693] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046337 ! phosphatidylethanolamine metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process + +[Term] +id: GO:0070293 +name: renal absorption +namespace: biological_process +def: "A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)." [GOC:dph, GOC:mah, GOC:yaf] +synonym: "nephron absorption" EXACT [GOC:mah] +synonym: "renal reabsorption" EXACT [GOC:dph] +is_a: GO:0003014 ! renal system process + +[Term] +id: GO:0070294 +name: renal sodium ion absorption +namespace: biological_process +def: "A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:dph, GOC:mah] +synonym: "nephron sodium ion absorption" EXACT [GOC:mah] +synonym: "renal sodium ion reabsorption" EXACT [GOC:dph] +is_a: GO:0003096 ! renal sodium ion transport +is_a: GO:0070293 ! renal absorption + +[Term] +id: GO:0070295 +name: renal water absorption +namespace: biological_process +def: "A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:dph, GOC:mah] +synonym: "nephron water absorption" EXACT [GOC:mah] +synonym: "renal water reabsorption" EXACT [GOC:dph] +is_a: GO:0003097 ! renal water transport +is_a: GO:0070293 ! renal absorption + +[Term] +id: GO:0070296 +name: sarcoplasmic reticulum calcium ion transport +namespace: biological_process +def: "The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum." [GOC:BHF, GOC:vk] +is_a: GO:0006816 ! calcium ion transport + +[Term] +id: GO:0070297 +name: regulation of phosphorelay signal transduction system +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah] +synonym: "regulation of histidyl-aspartyl phosphorelay" EXACT [GOC:mah] +synonym: "regulation of two-component signal transduction system" EXACT [GOC:bf, GOC:mah] +synonym: "regulation of two-component signal transduction system (phosphorelay)" NARROW [] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000160 ! phosphorelay signal transduction system +relationship: regulates GO:0000160 ! phosphorelay signal transduction system + +[Term] +id: GO:0070298 +name: negative regulation of phosphorelay signal transduction system +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah] +synonym: "down regulation of two-component signal transduction" EXACT [GOC:mah] +synonym: "down-regulation of two-component signal transduction" EXACT [GOC:mah] +synonym: "downregulation of two-component signal transduction" EXACT [GOC:mah] +synonym: "inhibition of two-component signal transduction" NARROW [GOC:mah] +synonym: "negative regulation of histidyl-aspartyl phosphorelay" EXACT [GOC:mah] +synonym: "negative regulation of two-component signal transduction system (phosphorelay)" NARROW [] +is_a: GO:0070297 ! regulation of phosphorelay signal transduction system +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000160 ! phosphorelay signal transduction system +relationship: negatively_regulates GO:0000160 ! phosphorelay signal transduction system + +[Term] +id: GO:0070299 +name: positive regulation of phosphorelay signal transduction system +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system." [GOC:mah] +synonym: "activation of two-component signal transduction" NARROW [GOC:mah] +synonym: "positive regulation of histidyl-aspartyl phosphorelay" EXACT [GOC:mah] +synonym: "positive regulation of two-component signal transduction system (phosphorelay)" NARROW [] +synonym: "stimulation of two-component signal transduction" NARROW [GOC:mah] +synonym: "up regulation of two-component signal transduction" EXACT [GOC:mah] +synonym: "up-regulation of two-component signal transduction" EXACT [GOC:mah] +synonym: "upregulation of two-component signal transduction" EXACT [GOC:mah] +is_a: GO:0070297 ! regulation of phosphorelay signal transduction system +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000160 ! phosphorelay signal transduction system +relationship: positively_regulates GO:0000160 ! phosphorelay signal transduction system + +[Term] +id: GO:0070300 +name: phosphatidic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids." [CHEBI:16337, GOC:jp, ISBN:0198506732] +synonym: "phosphatidate binding" EXACT [GOC:jp] +is_a: GO:0005543 ! phospholipid binding + +[Term] +id: GO:0070301 +name: cellular response to hydrogen peroxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus." [CHEBI:16240, GOC:mah] +is_a: GO:0034614 ! cellular response to reactive oxygen species +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0042542 ! response to hydrogen peroxide +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0097237 ! cellular response to toxic substance + +[Term] +id: GO:0070302 +name: regulation of stress-activated protein kinase signaling cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade." [GOC:mah] +synonym: "regulation of SAPK signaling pathway" EXACT [GOC:mah] +synonym: "regulation of stress-activated protein kinase signaling pathway" EXACT [] +synonym: "regulation of stress-activated protein kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0080135 ! regulation of cellular response to stress +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031098 ! stress-activated protein kinase signaling cascade +relationship: regulates GO:0031098 ! stress-activated protein kinase signaling cascade + +[Term] +id: GO:0070303 +name: negative regulation of stress-activated protein kinase signaling cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade." [GOC:mah] +synonym: "down regulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +synonym: "down-regulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +synonym: "downregulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +synonym: "inhibition of stress-activated protein kinase signaling pathway" NARROW [GOC:mah] +synonym: "negative regulation of SAPK signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of stress-activated protein kinase signaling pathway" EXACT [] +synonym: "negative regulation of stress-activated protein kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0070302 ! regulation of stress-activated protein kinase signaling cascade +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031098 ! stress-activated protein kinase signaling cascade +relationship: negatively_regulates GO:0031098 ! stress-activated protein kinase signaling cascade + +[Term] +id: GO:0070304 +name: positive regulation of stress-activated protein kinase signaling cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade." [GOC:mah] +synonym: "activation of stress-activated protein kinase signaling pathway" NARROW [GOC:mah] +synonym: "positive regulation of SAPK signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of stress-activated protein kinase signaling pathway" EXACT [] +synonym: "positive regulation of stress-activated protein kinase signalling pathway" EXACT [GOC:mah] +synonym: "stimulation of stress-activated protein kinase signaling pathway" NARROW [GOC:mah] +synonym: "up regulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +synonym: "up-regulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +synonym: "upregulation of stress-activated protein kinase signaling pathway" EXACT [GOC:mah] +is_a: GO:0070302 ! regulation of stress-activated protein kinase signaling cascade +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031098 ! stress-activated protein kinase signaling cascade +relationship: positively_regulates GO:0031098 ! stress-activated protein kinase signaling cascade + +[Term] +id: GO:0070305 +name: response to cGMP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus." [GOC:sl] +synonym: "response to 3',5' cGMP" EXACT [GOC:mah] +synonym: "response to 3',5'-cGMP" EXACT [GOC:mah] +synonym: "response to cyclic GMP" EXACT [GOC:mah] +synonym: "response to guanosine 3',5'-cyclophosphate" EXACT [GOC:mah] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0070306 +name: lens fiber cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities." [GOC:mah, PMID:7693735] +synonym: "lens fibre cell differentiation" EXACT [GOC:mah] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0002088 ! lens development in camera-type eye + +[Term] +id: GO:0070307 +name: lens fiber cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735] +synonym: "lens fibre cell development" EXACT [GOC:mah] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0070306 ! lens fiber cell differentiation + +[Term] +id: GO:0070308 +name: lens fiber cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735] +synonym: "lens fibre cell fate commitment" EXACT [GOC:mah] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0070306 ! lens fiber cell differentiation + +[Term] +id: GO:0070309 +name: lens fiber cell morphogenesis +namespace: biological_process +def: "The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GOC:mah, PMID:7693735] +synonym: "elongation of lens fiber cell" NARROW [GOC:mah, GOC:vk] +synonym: "lens fiber cell morphogenesis during differentiation" EXACT systematic_synonym [GOC:mah] +synonym: "lens fibre cell morphogenesis" EXACT [GOC:mah] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0002089 ! lens morphogenesis in camera-type eye +relationship: part_of GO:0070307 ! lens fiber cell development + +[Term] +id: GO:0070310 +name: ATR-ATRIP complex +namespace: cellular_component +def: "A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A." [GOC:mah, PMID:14724280] +synonym: "Mec1-Lcd1 complex" NARROW [PMID:17339343] +synonym: "Rad3-Rad26 complex" NARROW [PMID:17339343] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070311 +name: nucleosomal methylation activator complex +namespace: cellular_component +def: "A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription." [GOC:mah, PMID:14729568] +synonym: "NUMAC" EXACT [PMID:14729568] +is_a: GO:0035097 ! histone methyltransferase complex + +[Term] +id: GO:0070312 +name: RAD52-ERCC4-ERCC1 complex +namespace: cellular_component +def: "A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein." [PMID:14734547] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +is_a: GO:0000109 ! nucleotide-excision repair complex + +[Term] +id: GO:0070313 +name: RGS6-DNMT1-DMAP1 complex +namespace: cellular_component +def: "A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1." [GOC:mah, PMID:14734556] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070314 +name: G1 to G0 transition +namespace: biological_process +def: "A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence." [GOC:mah, GOC:mtg_cell_cycle, ISBN:0815316194] +synonym: "cell cycle quiescence" RELATED [GOC:mah] +synonym: "establishment of cell quiescence" EXACT [GOC:mah] +synonym: "G1/G0 transition" EXACT [GOC:mah] +synonym: "stationary phase" RELATED [GOC:mah] +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0070315 +name: G1 to G0 transition involved in cell differentiation +namespace: biological_process +def: "A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation." [GOC:mah, ISBN:0815316194] +synonym: "G1/G0 transition involved in cell differentiation" EXACT [GOC:mah] +is_a: GO:0070314 ! G1 to G0 transition +intersection_of: GO:0070314 ! G1 to G0 transition +intersection_of: part_of GO:0030154 ! cell differentiation +relationship: part_of GO:0030154 ! cell differentiation + +[Term] +id: GO:0070316 +name: regulation of G0 to G1 transition +namespace: biological_process +def: "A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah] +is_a: GO:0010564 ! regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045023 ! G0 to G1 transition +relationship: regulates GO:0045023 ! G0 to G1 transition + +[Term] +id: GO:0070317 +name: negative regulation of G0 to G1 transition +namespace: biological_process +def: "A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah] +synonym: "maintenance of cell cycle quiescence" EXACT [GOC:mah] +synonym: "maintenance of cell quiescence" EXACT [GOC:mah] +synonym: "maintenance of G0 arrest" EXACT [GOC:mah] +synonym: "maintenance of G0 phase" EXACT [GOC:mah] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0070316 ! regulation of G0 to G1 transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045023 ! G0 to G1 transition +relationship: negatively_regulates GO:0045023 ! G0 to G1 transition + +[Term] +id: GO:0070318 +name: positive regulation of G0 to G1 transition +namespace: biological_process +def: "A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase." [GOC:mah] +is_a: GO:0070316 ! regulation of G0 to G1 transition +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045023 ! G0 to G1 transition +relationship: positively_regulates GO:0045023 ! G0 to G1 transition + +[Term] +id: GO:0070319 +name: Golgi to plasma membrane transport vesicle +namespace: cellular_component +def: "A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] +synonym: "Golgi to plasma membrane constitutive secretory pathway transport vesicle" EXACT [] +synonym: "Golgi-plasma membrane transport vesicle" EXACT [GOC:mah] +is_a: GO:0070382 ! exocytic vesicle + +[Term] +id: GO:0070320 +name: inward rectifier potassium channel inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel." [GOC:mah] +is_a: GO:0019870 ! potassium channel inhibitor activity + +[Term] +id: GO:0070321 +name: obsolete regulation of translation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah] +comment: This term was obsoleted because it was redundant with GO:1903832 ; regulation of cellular response to amino acid starvation. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19092 xsd:anyURI +is_obsolete: true +consider: GO:1903832 + +[Term] +id: GO:0070322 +name: obsolete negative regulation of translation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah] +comment: This term was obsoleted because it was redundant with GO:1903574 ; negative regulation of cellular response to amino acid starvation. +synonym: "down regulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +synonym: "down-regulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +synonym: "downregulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +synonym: "inhibition of translation in response to nitrogen starvation" NARROW [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19092 xsd:anyURI +is_obsolete: true +consider: GO:1903574 + +[Term] +id: GO:0070323 +name: obsolete positive regulation of translation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen." [GOC:mah] +comment: This term was obsoleted because it was redundant with GO:1903833 ; positive regulation of cellular response to amino acid starvation. +synonym: "activation of translation in response to nitrogen starvation" NARROW [GOC:mah] +synonym: "stimulation of translation in response to nitrogen starvation" NARROW [GOC:mah] +synonym: "up regulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +synonym: "up-regulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +synonym: "upregulation of translation in response to nitrogen starvation" EXACT [GOC:mah] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19092 xsd:anyURI +is_obsolete: true +consider: GO:1903833 + +[Term] +id: GO:0070324 +name: thyroid hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland." [GOC:rph] +subset: goslim_chembl +synonym: "thyroxine binding" NARROW [GOC:mah] +synonym: "triiodothyronine binding" NARROW [GOC:mah] +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0070325 +name: lipoprotein particle receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipoprotein particle receptor." [GOC:BHF, GOC:rl] +is_a: GO:0005102 ! signaling receptor binding + +[Term] +id: GO:0070326 +name: very-low-density lipoprotein particle receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a very-low-density lipoprotein receptor." [GOC:BHF, GOC:mah] +synonym: "apolipoprotein E receptor binding" RELATED [GOC:rl] +synonym: "very-low-density lipoprotein receptor binding" EXACT [GOC:bf, GOC:dph] +synonym: "VLDL receptor binding" EXACT [GOC:mah] +synonym: "VLDLR binding" EXACT [GOC:mah] +is_a: GO:0070325 ! lipoprotein particle receptor binding + +[Term] +id: GO:0070327 +name: thyroid hormone transport +namespace: biological_process +def: "The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:rph] +synonym: "thyroxine transport" NARROW [GOC:mah] +synonym: "triiodothyronine transport" NARROW [GOC:mah] +is_a: GO:0009914 ! hormone transport + +[Term] +id: GO:0070328 +name: triglyceride homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell." [GOC:BHF, GOC:mah] +synonym: "triacylglycerol homeostasis" EXACT [GOC:rl] +is_a: GO:0055090 ! acylglycerol homeostasis + +[Term] +id: GO:0070329 +name: tRNA seleno-modification +namespace: biological_process +def: "The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule." [GOC:jsg, PMID:14594807] +synonym: "tRNA base modification to selenouridine" EXACT [GOC:mah] +is_a: GO:0001887 ! selenium compound metabolic process +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0070330 +name: aromatase activity +namespace: molecular_function +def: "Catalysis of the reduction of an aliphatic ring to yield an aromatic ring." [GOC:cb] +synonym: "estrogen synthetase activity" NARROW [] +xref: EC:1.14.14.1 +xref: MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN +xref: UM-BBD_enzymeID:e0551 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0070331 +name: CD20-Lck-Fyn complex +namespace: cellular_component +def: "A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn." [GOC:mah, PMID:7545683] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0070332 +name: CD20-Lck-Lyn-Fyn complex +namespace: cellular_component +def: "A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn." [GOC:mah, PMID:7545683] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0070333 +name: alpha6-beta4 integrin-Shc-Grb2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2." [PMID:7556090] +synonym: "ITGA6-ITGB4-SHC-GRB2 complex" NARROW [CORUM:3096] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070334 +name: alpha6-beta4 integrin-laminin 5 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5." [GOC:mah, PMID:7556090] +synonym: "alpha6-beta4 integrin-laminin-332 complex" EXACT [GOC:sl, PMID:15979864] +synonym: "ITGA6-ITGB4-LAMA5 complex" NARROW [CORUM:2322] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070335 +name: aspartate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4." [CHEBI:29995, GOC:mah] +synonym: "aspartic acid binding" EXACT [GOC:mah] +is_a: GO:0016597 ! amino acid binding + +[Term] +id: GO:0070336 +name: flap-structured DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule." [GOC:mah, PMID:15189154] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0070337 +name: 3'-flap-structured DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule." [GOC:mah, PMID:15189154] +is_a: GO:0070336 ! flap-structured DNA binding + +[Term] +id: GO:0070338 +name: 5'-flap-structured DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers." [GOC:mah, PMID:15189154] +is_a: GO:0070336 ! flap-structured DNA binding + +[Term] +id: GO:0070339 +name: response to bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus." [GOC:add, PMID:12077222] +is_a: GO:0032493 ! response to bacterial lipoprotein + +[Term] +id: GO:0070340 +name: detection of bacterial lipopeptide +namespace: biological_process +def: "The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal." [GOC:add, PMID:12077222] +is_a: GO:0042494 ! detection of bacterial lipoprotein +is_a: GO:0070339 ! response to bacterial lipopeptide + +[Term] +id: GO:0070341 +name: fat cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl] +synonym: "adipocyte proliferation" EXACT [GOC:sl] +synonym: "adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0008283 ! cell population proliferation + +[Term] +id: GO:0070342 +name: brown fat cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species." [CL:0000449, GOC:mah, GOC:sl] +synonym: "brown adipocyte proliferation" EXACT [GOC:sl] +synonym: "brown adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070341 ! fat cell proliferation +property_value: RO:0002161 NCBITaxon:8782 + +[Term] +id: GO:0070343 +name: white fat cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population." [CL:0000448, GOC:mah, GOC:sl] +synonym: "white adipocyte proliferation" EXACT [GOC:sl] +synonym: "white adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070341 ! fat cell proliferation + +[Term] +id: GO:0070344 +name: regulation of fat cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl] +synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070341 ! fat cell proliferation +relationship: regulates GO:0070341 ! fat cell proliferation + +[Term] +id: GO:0070345 +name: negative regulation of fat cell proliferation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah] +synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah] +synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah] +synonym: "inhibition of fat cell proliferation" NARROW [GOC:mah] +synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl] +synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0070344 ! regulation of fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070341 ! fat cell proliferation +relationship: negatively_regulates GO:0070341 ! fat cell proliferation + +[Term] +id: GO:0070346 +name: positive regulation of fat cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "activation of fat cell proliferation" NARROW [GOC:mah] +synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl] +synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl] +synonym: "stimulation of fat cell proliferation" NARROW [GOC:mah] +synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah] +synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah] +synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0070344 ! regulation of fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070341 ! fat cell proliferation +relationship: positively_regulates GO:0070341 ! fat cell proliferation + +[Term] +id: GO:0070347 +name: regulation of brown fat cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "regulation of brown adipocyte proliferation" EXACT [GOC:sl] +synonym: "regulation of brown adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070344 ! regulation of fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070342 ! brown fat cell proliferation +relationship: regulates GO:0070342 ! brown fat cell proliferation + +[Term] +id: GO:0070348 +name: negative regulation of brown fat cell proliferation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "down regulation of brown fat cell proliferation" EXACT [GOC:mah] +synonym: "down-regulation of brown fat cell proliferation" EXACT [GOC:mah] +synonym: "downregulation of brown fat cell proliferation" EXACT [GOC:mah] +synonym: "inhibition of brown fat cell proliferation" NARROW [GOC:mah] +synonym: "negative regulation of brown adipocyte proliferation" EXACT [GOC:sl] +synonym: "negative regulation of brown adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070345 ! negative regulation of fat cell proliferation +is_a: GO:0070347 ! regulation of brown fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070342 ! brown fat cell proliferation +relationship: negatively_regulates GO:0070342 ! brown fat cell proliferation + +[Term] +id: GO:0070349 +name: positive regulation of brown fat cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of brown fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "activation of brown fat cell proliferation" NARROW [GOC:mah] +synonym: "positive regulation of brown adipocyte proliferation" EXACT [GOC:sl] +synonym: "positive regulation of brown adipose cell proliferation" EXACT [GOC:sl] +synonym: "stimulation of brown fat cell proliferation" NARROW [GOC:mah] +synonym: "up regulation of brown fat cell proliferation" EXACT [GOC:mah] +synonym: "up-regulation of brown fat cell proliferation" EXACT [GOC:mah] +synonym: "upregulation of brown fat cell proliferation" EXACT [GOC:mah] +is_a: GO:0070346 ! positive regulation of fat cell proliferation +is_a: GO:0070347 ! regulation of brown fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070342 ! brown fat cell proliferation +relationship: positively_regulates GO:0070342 ! brown fat cell proliferation + +[Term] +id: GO:0070350 +name: regulation of white fat cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "regulation of white adipocyte proliferation" EXACT [GOC:sl] +synonym: "regulation of white adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070344 ! regulation of fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070343 ! white fat cell proliferation +relationship: regulates GO:0070343 ! white fat cell proliferation + +[Term] +id: GO:0070351 +name: negative regulation of white fat cell proliferation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "down regulation of white fat cell proliferation" EXACT [GOC:mah] +synonym: "down-regulation of white fat cell proliferation" EXACT [GOC:mah] +synonym: "downregulation of white fat cell proliferation" EXACT [GOC:mah] +synonym: "inhibition of white fat cell proliferation" NARROW [GOC:mah] +synonym: "negative regulation of white adipocyte proliferation" EXACT [GOC:sl] +synonym: "negative regulation of white adipose cell proliferation" EXACT [GOC:sl] +is_a: GO:0070345 ! negative regulation of fat cell proliferation +is_a: GO:0070350 ! regulation of white fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070343 ! white fat cell proliferation +relationship: negatively_regulates GO:0070343 ! white fat cell proliferation + +[Term] +id: GO:0070352 +name: positive regulation of white fat cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of white fat cell proliferation." [GOC:mah, GOC:sl] +synonym: "activation of white fat cell proliferation" NARROW [GOC:mah] +synonym: "positive regulation of white adipocyte proliferation" EXACT [GOC:sl] +synonym: "positive regulation of white adipose cell proliferation" EXACT [GOC:sl] +synonym: "stimulation of white fat cell proliferation" NARROW [GOC:mah] +synonym: "up regulation of white fat cell proliferation" EXACT [GOC:mah] +synonym: "up-regulation of white fat cell proliferation" EXACT [GOC:mah] +synonym: "upregulation of white fat cell proliferation" EXACT [GOC:mah] +is_a: GO:0070346 ! positive regulation of fat cell proliferation +is_a: GO:0070350 ! regulation of white fat cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070343 ! white fat cell proliferation +relationship: positively_regulates GO:0070343 ! white fat cell proliferation + +[Term] +id: GO:0070353 +name: GATA1-TAL1-TCF3-Lmo2 complex +namespace: cellular_component +def: "A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis." [PMID:7568177] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070354 +name: GATA2-TAL1-TCF3-Lmo2 complex +namespace: cellular_component +def: "A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis." [PMID:7568177] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070355 +name: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex +namespace: cellular_component +def: "A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof)." [PMID:7654227] +synonym: "SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2)" NARROW [CORUM:1247] +synonym: "STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex" NARROW [CORUM:1247] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070356 +name: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex +namespace: cellular_component +def: "A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof)." [PMID:7654227] +synonym: "SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2)" NARROW [CORUM:1244] +synonym: "STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex" NARROW [CORUM:1244] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070357 +name: alphav-beta3 integrin-CD47 complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP)." [PMID:2277087, PMID:7691831] +synonym: "ITGB3-ITGAV-CD47 complex" NARROW [CORUM:2356] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070358 +name: actin polymerization-dependent cell motility +namespace: biological_process +def: "A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell." [GOC:mah, PMID:15773977] +synonym: "cell motility by actin tail formation" EXACT [PMID:15773977] +is_a: GO:0048870 ! cell motility + +[Term] +id: GO:0070359 +name: actin polymerization-dependent cell motility involved in migration of symbiont in host +namespace: biological_process +def: "A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell." [GOC:jl, GOC:mah, PMID:15773977] +synonym: "actin polymerization-dependent cell motility involved in migration of symbiont within host" EXACT [] +is_a: GO:0070358 ! actin polymerization-dependent cell motility +relationship: part_of GO:0070360 ! migration of symbiont within host by polymerization of host actin + +[Term] +id: GO:0070360 +name: migration of symbiont within host by polymerization of host actin +namespace: biological_process +def: "The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:mah] +is_a: GO:0044001 ! migration in host + +[Term] +id: GO:0070365 +name: hepatocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884] +synonym: "liver cell differentiation" EXACT [GOC:mah] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0001889 ! liver development + +[Term] +id: GO:0070366 +name: regulation of hepatocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] +synonym: "regulation of liver cell differentiation" EXACT [GOC:sl] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070365 ! hepatocyte differentiation +relationship: regulates GO:0070365 ! hepatocyte differentiation + +[Term] +id: GO:0070367 +name: negative regulation of hepatocyte differentiation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] +synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah] +synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah] +synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah] +synonym: "inhibition of hepatocyte differentiation" NARROW [GOC:mah] +synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0070366 ! regulation of hepatocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070365 ! hepatocyte differentiation +relationship: negatively_regulates GO:0070365 ! hepatocyte differentiation + +[Term] +id: GO:0070368 +name: positive regulation of hepatocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] +synonym: "activation of hepatocyte differentiation" NARROW [GOC:mah] +synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl] +synonym: "stimulation of hepatocyte differentiation" NARROW [GOC:mah] +synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah] +synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah] +synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0070366 ! regulation of hepatocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070365 ! hepatocyte differentiation +relationship: positively_regulates GO:0070365 ! hepatocyte differentiation + +[Term] +id: GO:0070369 +name: beta-catenin-TCF7L2 complex +namespace: cellular_component +def: "A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:rl, PMID:9065401, PMID:9065402] +synonym: "beta-catenin-TCF4 complex" EXACT [PMID:9065401, PMID:9065402] +is_a: GO:0071664 ! catenin-TCF7L2 complex +is_a: GO:1990907 ! beta-catenin-TCF complex + +[Term] +id: GO:0070370 +name: cellular heat acclimation +namespace: biological_process +def: "Any process that increases heat tolerance of a cell in response to high temperatures." [GOC:jp] +synonym: "cellular thermotolerance" EXACT [GOC:jp] +is_a: GO:0010286 ! heat acclimation +is_a: GO:0034605 ! cellular response to heat + +[Term] +id: GO:0070371 +name: ERK1 and ERK2 cascade +namespace: biological_process +def: "An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0121245462, ISBN:0896039986, PMID:20811974, PMID:28903453] +comment: Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2 and should not be confused with cascades that involve other ERK kinases. +synonym: "ERK cascade" BROAD [GOC:add] +synonym: "ERK1 and ERK2 signaling pathway" EXACT [GOC:mah] +synonym: "ERK1 and ERK2 signalling pathway" EXACT [GOC:mah] +synonym: "ERK1 cascade" NARROW [GOC:add] +synonym: "ERK1/2 cascade" EXACT [GOC:add] +synonym: "ERK2 cascade" NARROW [GOC:add] +synonym: "extracellular signal-regulated kinase 1/2 (ERK1/2) cascade" EXACT [PMID:20811974] +synonym: "extracellular signal-regulated kinase 1/2 cascade" EXACT [PMID:20811974] +synonym: "MAPK1 cascade" NARROW [GOC:add] +synonym: "MAPK3 cascade" NARROW [GOC:add] +is_a: GO:0000165 ! MAPK cascade + +[Term] +id: GO:0070372 +name: regulation of ERK1 and ERK2 cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986] +synonym: "regulation of ERK cascade" BROAD [GOC:add] +synonym: "regulation of ERK1 and ERK2 signaling pathway" EXACT [GOC:mah] +synonym: "regulation of ERK1 and ERK2 signalling pathway" EXACT [GOC:mah] +synonym: "regulation of ERK1 cascade" NARROW [GOC:add] +synonym: "regulation of ERK1/2 cascade" EXACT [GOC:add] +synonym: "regulation of ERK2 cascade" NARROW [GOC:add] +synonym: "regulation of MAPK1 cascade" NARROW [GOC:add] +synonym: "regulation of MAPK3 cascade" NARROW [GOC:add] +is_a: GO:0043408 ! regulation of MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070371 ! ERK1 and ERK2 cascade +relationship: regulates GO:0070371 ! ERK1 and ERK2 cascade + +[Term] +id: GO:0070373 +name: negative regulation of ERK1 and ERK2 cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986] +synonym: "down regulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +synonym: "down-regulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +synonym: "downregulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +synonym: "inhibition of ERK1 and ERK2 cascade" NARROW [GOC:mah] +synonym: "negative regulation of ERK cascade" BROAD [GOC:add] +synonym: "negative regulation of ERK1 and ERK2 signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of ERK1 and ERK2 signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of ERK1 cascade" NARROW [GOC:add] +synonym: "negative regulation of ERK1/2 cascade" EXACT [GOC:add] +synonym: "negative regulation of ERK2 cascade" NARROW [GOC:add] +synonym: "negative regulation of MAPK1 cascade" NARROW [GOC:add] +synonym: "negative regulation of MAPK3 cascade" NARROW [GOC:add] +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0070372 ! regulation of ERK1 and ERK2 cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070371 ! ERK1 and ERK2 cascade +relationship: negatively_regulates GO:0070371 ! ERK1 and ERK2 cascade + +[Term] +id: GO:0070374 +name: positive regulation of ERK1 and ERK2 cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." [GOC:mah] +synonym: "activation of ERK1 and ERK2 cascade" NARROW [GOC:mah] +synonym: "positive regulation of ERK cascade" BROAD [GOC:add] +synonym: "positive regulation of ERK1 and ERK2 signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of ERK1 and ERK2 signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of ERK1 cascade" NARROW [GOC:add] +synonym: "positive regulation of ERK1/2 cascade" EXACT [GOC:add] +synonym: "positive regulation of ERK2 cascade" NARROW [GOC:add] +synonym: "positive regulation of MAPK1 cascade" NARROW [GOC:add] +synonym: "positive regulation of MAPK3 cascade" NARROW [GOC:add] +synonym: "stimulation of ERK1 and ERK2 cascade" NARROW [GOC:mah] +synonym: "up regulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +synonym: "up-regulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +synonym: "upregulation of ERK1 and ERK2 cascade" EXACT [GOC:mah] +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0070372 ! regulation of ERK1 and ERK2 cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070371 ! ERK1 and ERK2 cascade +relationship: positively_regulates GO:0070371 ! ERK1 and ERK2 cascade + +[Term] +id: GO:0070375 +name: ERK5 cascade +namespace: biological_process +def: "An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0896039986, PMID:16376520, PMID:16880823, PMID:20811974, PMID:28903453] +synonym: "big MAP kinase signaling cascade" EXACT [PMID:20811974] +synonym: "BMK cascade" EXACT [PMID:20811974] +synonym: "BMK signaling pathway" EXACT [GOC:mah] +synonym: "BMK signalling pathway" EXACT [GOC:mah] +synonym: "BMK1 cascade" EXACT [GOC:add] +synonym: "ERK5 signaling pathway" EXACT [PMID:16376520] +synonym: "extracellular signal-regulated kinase 5 cascade" EXACT [PMID:20811974] +synonym: "MAPK7 cascade" EXACT [GOC:add] +is_a: GO:0000165 ! MAPK cascade + +[Term] +id: GO:0070376 +name: regulation of ERK5 cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986] +synonym: "regulation of BMK cascade" EXACT [GOC:signaling] +synonym: "regulation of BMK signaling pathway" EXACT [GOC:mah] +synonym: "regulation of BMK signalling pathway" EXACT [GOC:mah] +synonym: "regulation of BMK1 cascade" EXACT [GOC:add] +synonym: "regulation of ERK5 signaling pathway" EXACT [PMID:16376520] +synonym: "regulation of MAPK7 cascade" EXACT [GOC:add] +is_a: GO:0043408 ! regulation of MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070375 ! ERK5 cascade +relationship: regulates GO:0070375 ! ERK5 cascade + +[Term] +id: GO:0070377 +name: negative regulation of ERK5 cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:add, ISBN:0121245462, ISBN:0896039986] +synonym: "down regulation of BMK cascade" EXACT [GOC:mah] +synonym: "down-regulation of BMK cascade" EXACT [GOC:mah] +synonym: "downregulation of BMK cascade" EXACT [GOC:mah] +synonym: "inhibition of BMK cascade" NARROW [GOC:mah] +synonym: "negative regulation of BMK cascade" EXACT [GOC:signaling] +synonym: "negative regulation of BMK signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of BMK signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of BMK1 cascade" EXACT [GOC:add] +synonym: "negative regulation of ERK5 signaling pathway" EXACT [PMID:16376520] +synonym: "negative regulation of MAPK7 cascade" EXACT [GOC:add] +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0070376 ! regulation of ERK5 cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070375 ! ERK5 cascade +relationship: negatively_regulates GO:0070375 ! ERK5 cascade + +[Term] +id: GO:0070378 +name: positive regulation of ERK5 cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade." [GOC:mah] +synonym: "activation of BMK cascade" NARROW [GOC:mah] +synonym: "positive regulation of BMK cascade" EXACT [GOC:signaling] +synonym: "positive regulation of BMK signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of BMK signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of BMK1 cascade" EXACT [GOC:add] +synonym: "positive regulation of ERK5 signaling pathway" EXACT [PMID:16376520] +synonym: "positive regulation of MAPK7 cascade" EXACT [GOC:add] +synonym: "stimulation of BMK cascade" NARROW [GOC:mah] +synonym: "up regulation of BMK cascade" EXACT [GOC:mah] +synonym: "up-regulation of BMK cascade" EXACT [GOC:mah] +synonym: "upregulation of BMK cascade" EXACT [GOC:mah] +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0070376 ! regulation of ERK5 cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070375 ! ERK5 cascade +relationship: positively_regulates GO:0070375 ! ERK5 cascade + +[Term] +id: GO:0070379 +name: high mobility group box 1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1)." [GOC:add, PMID:18431461] +synonym: "HMGB1 binding" EXACT [GOC:add] +is_a: GO:0019955 ! cytokine binding + +[Term] +id: GO:0070380 +name: high mobility group box 1 receptor activity +namespace: molecular_function +def: "Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling, PMID:18431461] +synonym: "HMGB1 receptor activity" EXACT [GOC:add] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0070379 ! high mobility group box 1 binding + +[Term] +id: GO:0070381 +name: endosome to plasma membrane transport vesicle +namespace: cellular_component +def: "A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah, PMID:10679016, PMID:12110576] +synonym: "endosome to plasma membrane constitutive secretory pathway transport vesicle" EXACT [] +synonym: "endosome-plasma membrane transport vesicle" EXACT [GOC:mah] +is_a: GO:0070382 ! exocytic vesicle + +[Term] +id: GO:0070382 +name: exocytic vesicle +namespace: cellular_component +def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] +synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT [] +synonym: "exocytotic vesicle" EXACT [GOC:kad] +is_a: GO:0030133 ! transport vesicle +is_a: GO:0099503 ! secretory vesicle + +[Term] +id: GO:0070383 +name: DNA cytosine deamination +namespace: biological_process +def: "The removal of an amino group from a cytosine residue in DNA, forming a uracil residue." [GOC:mah] +is_a: GO:0045006 ! DNA deamination + +[Term] +id: GO:0070384 +name: Harderian gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species." [GOC:hjd, PMID:16856596, PMID:7559104] +comment: Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages. +is_a: GO:0048732 ! gland development + +[Term] +id: GO:0070385 +name: egasyn-beta-glucuronidase complex +namespace: cellular_component +def: "A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum." [PMID:7744842] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0070386 +name: procollagen-proline 4-dioxygenase complex, alpha(I) type +namespace: cellular_component +def: "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline)." [PMID:14500733, PMID:7753822] +synonym: "procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(I) type" EXACT [PMID:7753822] +synonym: "prolyl 4-hydroxylase complex (alpha(I)-type)" BROAD [CORUM:472] +is_a: GO:0016222 ! procollagen-proline 4-dioxygenase complex + +[Term] +id: GO:0070387 +name: procollagen-proline 4-dioxygenase complex, alpha(II) type +namespace: cellular_component +def: "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations." [PMID:14500733, PMID:7753822] +synonym: "procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(II) type" EXACT [PMID:7753822] +synonym: "prolyl 4-hydroxylase complex (alpha(II)-type)" BROAD [CORUM:473] +is_a: GO:0016222 ! procollagen-proline 4-dioxygenase complex + +[Term] +id: GO:0070388 +name: procollagen-proline 4-dioxygenase complex, alpha(III) type +namespace: cellular_component +def: "A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform." [PMID:14500733] +synonym: "procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(III) type" EXACT [PMID:14500733] +synonym: "prolyl 4-hydroxylase complex (alpha(III)-type)" BROAD [CORUM:474] +is_a: GO:0016222 ! procollagen-proline 4-dioxygenase complex + +[Term] +id: GO:0070390 +name: transcription export complex 2 +namespace: cellular_component +def: "A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p." [GOC:dgf, GOC:mah, PMID:17786152, PMID:19289793, PMID:28334829] +synonym: "Sac3-Thp1-Sus1-Sem1-Cdc31 complex" EXACT [PMID:17786152] +synonym: "TREX-2 complex" EXACT [GOC:dgf] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070391 +name: response to lipoteichoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "response to LTA" EXACT [GOC:add] +is_a: GO:0002237 ! response to molecule of bacterial origin +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0070392 +name: detection of lipoteichoic acid +namespace: biological_process +def: "The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "detection of LTA" EXACT [GOC:add] +is_a: GO:0032490 ! detection of molecule of bacterial origin +is_a: GO:0070391 ! response to lipoteichoic acid + +[Term] +id: GO:0070393 +name: teichoic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues." [GOC:add, PMID:14665680] +synonym: "teichoic acid breakdown" EXACT [GOC:add] +synonym: "teichoic acid catabolism" EXACT [GOC:add] +synonym: "teichoic acid degradation" EXACT [GOC:add] +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:0046374 ! teichoic acid metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process + +[Term] +id: GO:0070394 +name: lipoteichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "lipoteichoic acid metabolism" EXACT [GOC:add] +synonym: "LTA metabolic process" EXACT [GOC:add] +is_a: GO:0046374 ! teichoic acid metabolic process + +[Term] +id: GO:0070395 +name: lipoteichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "lipoteichoic acid anabolism" EXACT [GOC:add] +synonym: "lipoteichoic acid biosynthesis" EXACT [GOC:add] +synonym: "lipoteichoic acid formation" EXACT [GOC:add] +synonym: "lipoteichoic acid synthesis" EXACT [GOC:add] +synonym: "LTA biosynthetic process" BROAD [GOC:add] +is_a: GO:0019350 ! teichoic acid biosynthetic process +is_a: GO:0070394 ! lipoteichoic acid metabolic process + +[Term] +id: GO:0070396 +name: lipoteichoic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680] +synonym: "lipoteichoic acid breakdown" EXACT [GOC:add] +synonym: "lipoteichoic acid catabolism" EXACT [GOC:add] +synonym: "lipoteichoic acid degradation" EXACT [GOC:add] +is_a: GO:0070393 ! teichoic acid catabolic process +is_a: GO:0070394 ! lipoteichoic acid metabolic process + +[Term] +id: GO:0070397 +name: wall teichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "wall teichoic acid metabolism" EXACT [GOC:add] +synonym: "WTA metabolic process" EXACT [GOC:add] +is_a: GO:0046374 ! teichoic acid metabolic process + +[Term] +id: GO:0070398 +name: wall teichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "wall teichoic acid anabolism" EXACT [GOC:add] +synonym: "wall teichoic acid biosynthesis" EXACT [GOC:add] +synonym: "wall teichoic acid formation" EXACT [GOC:add] +synonym: "wall teichoic acid synthesis" EXACT [GOC:add] +synonym: "WTA biosynthetic process" EXACT [GOC:add] +is_a: GO:0019350 ! teichoic acid biosynthetic process +is_a: GO:0070397 ! wall teichoic acid metabolic process + +[Term] +id: GO:0070399 +name: wall teichoic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680] +synonym: "wall teichoic acid breakdown" EXACT [GOC:add] +synonym: "wall teichoic acid catabolism" EXACT [GOC:add] +synonym: "wall teichoic acid degradation" EXACT [GOC:add] +is_a: GO:0070397 ! wall teichoic acid metabolic process + +[Term] +id: GO:0070400 +name: teichoic acid D-alanylation +namespace: biological_process +def: "The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid." [GOC:add, PMID:14665680, PMID:16020688] +synonym: "teichoic acid alanylation" EXACT [GOC:add] +is_a: GO:0019350 ! teichoic acid biosynthetic process + +[Term] +id: GO:0070401 +name: NADP+ binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] +synonym: "NADP (oxidized) binding" EXACT [GOC:mah] +synonym: "NADP binding" RELATED [GOC:mah] +synonym: "oxidized NADP binding" EXACT [GOC:mah] +synonym: "oxidized nicotinamide adenine dinucleotide phosphate binding" EXACT [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0050661 ! NADP binding + +[Term] +id: GO:0070402 +name: NADPH binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] +synonym: "NADP (reduced) binding" EXACT [GOC:mah] +synonym: "reduced NADP binding" EXACT [GOC:mah] +synonym: "reduced nicotinamide adenine dinucleotide phosphate binding" EXACT [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0050661 ! NADP binding + +[Term] +id: GO:0070403 +name: NAD+ binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] +synonym: "NAD (oxidized) binding" EXACT [GOC:mah] +synonym: "NAD binding" RELATED [GOC:mah] +synonym: "oxidized NAD binding" EXACT [GOC:mah] +synonym: "oxidized nicotinamide adenine dinucleotide binding" EXACT [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0051287 ! NAD binding + +[Term] +id: GO:0070404 +name: NADH binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] +synonym: "NAD (reduced) binding" EXACT [GOC:mah] +synonym: "reduced NAD binding" EXACT [GOC:mah] +synonym: "reduced nicotinamide adenine dinucleotide binding" EXACT [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0051287 ! NAD binding + +[Term] +id: GO:0070405 +name: ammonium ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ammonium ions (NH4+)." [CHEBI:28938, GOC:ecd] +synonym: "ammonium binding" RELATED [] +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0070406 +name: glutamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid." [CHEBI:28300, GOC:ecd] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding + +[Term] +id: GO:0070407 +name: oxidation-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein." [GOC:mah] +synonym: "oxidation-dependent protein breakdown" EXACT [GOC:mah] +synonym: "oxidation-dependent protein catabolism" EXACT [GOC:mah] +synonym: "oxidation-dependent protein degradation" EXACT [GOC:mah] +synonym: "oxidation-dependent proteolysis" EXACT [GOC:mah] +synonym: "oxidized protein catabolic process" EXACT [GOC:mah] +is_a: GO:0019941 ! modification-dependent protein catabolic process + +[Term] +id: GO:0070408 +name: carbamoyl phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [CHEBI:17672, GOC:mah, GOC:rph] +synonym: "carbamoyl phosphate metabolism" EXACT [GOC:mah] +xref: UM-BBD_pathwayID:bzn +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process + +[Term] +id: GO:0070409 +name: carbamoyl phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways." [CHEBI:17672, GOC:mah, GOC:rph] +synonym: "carbamoyl phosphate anabolism" EXACT [] +synonym: "carbamoyl phosphate biosynthesis" EXACT [] +synonym: "carbamoyl phosphate formation" EXACT [] +synonym: "carbamoyl phosphate synthesis" EXACT [] +synonym: "carbamyl phosphate biosynthetic process" EXACT [GOC:rph] +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0070408 ! carbamoyl phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process + +[Term] +id: GO:0070410 +name: co-SMAD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a common mediator SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992] +synonym: "common mediator SMAD binding" EXACT [GOC:rl] +synonym: "common partner SMAD binding" EXACT [GOC:rl] +synonym: "common-mediator SMAD binding" EXACT [GOC:rl] +synonym: "common-partner SMAD binding" EXACT [GOC:rl] +is_a: GO:0046332 ! SMAD binding + +[Term] +id: GO:0070411 +name: I-SMAD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an inhibitory SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992] +is_a: GO:0046332 ! SMAD binding + +[Term] +id: GO:0070412 +name: R-SMAD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein." [GOC:BHF, GOC:vk, PMID:19114992] +synonym: "pathway restricted SMAD binding" EXACT [GOC:rl] +synonym: "pathway-restricted SMAD binding" EXACT [GOC:rl] +synonym: "receptor regulated SMAD binding" EXACT [GOC:rl] +synonym: "receptor-regulated SMAD binding" EXACT [GOC:rl] +is_a: GO:0046332 ! SMAD binding + +[Term] +id: GO:0070413 +name: trehalose metabolism in response to stress +namespace: biological_process +def: "The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress." [GOC:jp, GOC:mah, PMID:9797333] +synonym: "trehalose metabolic process involved in response to stress" EXACT systematic_synonym [GOC:mah] +is_a: GO:0005991 ! trehalose metabolic process +intersection_of: GO:0005991 ! trehalose metabolic process +intersection_of: part_of GO:0006950 ! response to stress +relationship: part_of GO:0033554 ! cellular response to stress + +[Term] +id: GO:0070414 +name: trehalose metabolism in response to heat stress +namespace: biological_process +def: "The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:jp, GOC:mah, PMID:9797333] +synonym: "trehalose metabolic process involved in response to heat stress" EXACT systematic_synonym [GOC:mah] +is_a: GO:0070413 ! trehalose metabolism in response to stress +relationship: part_of GO:0034605 ! cellular response to heat + +[Term] +id: GO:0070415 +name: trehalose metabolism in response to cold stress +namespace: biological_process +def: "The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:jp, GOC:mah, PMID:9797333] +synonym: "trehalose metabolic process involved in response to cold stress" EXACT systematic_synonym [GOC:mah] +is_a: GO:0070413 ! trehalose metabolism in response to stress +is_a: GO:0070417 ! cellular response to cold + +[Term] +id: GO:0070416 +name: trehalose metabolism in response to water deprivation +namespace: biological_process +def: "The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water." [GOC:jp, GOC:mah, PMID:9797333] +synonym: "trehalose metabolic process involved in response to water deprivation" EXACT systematic_synonym [GOC:mah] +is_a: GO:0070413 ! trehalose metabolism in response to stress +intersection_of: GO:0005991 ! trehalose metabolic process +intersection_of: part_of GO:0009414 ! response to water deprivation +relationship: part_of GO:0009414 ! response to water deprivation + +[Term] +id: GO:0070417 +name: cellular response to cold +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism." [GOC:jp] +synonym: "cellular response to cold stress" EXACT [GOC:jp] +is_a: GO:0009409 ! response to cold +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0070418 +name: DNA-dependent protein kinase complex +namespace: cellular_component +def: "A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku." [GOC:mah, PMID:10854421, PMID:12235392] +synonym: "DNA-dependent protein kinase, DNA-end-binding complex" NARROW [] +synonym: "DNA-PK complex" EXACT [] +synonym: "DNA-PK-Ku antigen complex" EXACT [CORUM:355] +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070419 +name: nonhomologous end joining complex +namespace: cellular_component +def: "A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends." [GOC:mah, PMID:17072889, PMID:17938628] +synonym: "NHEJ complex" EXACT [GOC:mah] +synonym: "non-homologous end joining complex" EXACT [GOC:mah] +is_a: GO:1990391 ! DNA repair complex +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0070420 +name: Ku-DNA ligase complex +namespace: cellular_component +def: "A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria." [GOC:mah, PMID:17938628] +is_a: GO:0070419 ! nonhomologous end joining complex + +[Term] +id: GO:0070421 +name: DNA ligase III-XRCC1 complex +namespace: cellular_component +def: "A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair." [PMID:15141024, PMID:7760816] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070422 +name: G-protein beta/gamma-Raf-1 complex +namespace: cellular_component +def: "A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein." [GOC:mah, PMID:7782277] +comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'. +synonym: "G protein complex (GNG2, GNB2L1, RAF1)" RELATED [CORUM:1539] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0070423 +name: nucleotide-binding oligomerization domain containing signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein." [GOC:add, PMID:17944960, PMID:18585455] +synonym: "NOD signaling pathway" EXACT [GOC:add] +synonym: "nucleotide-binding oligomerization domain containing signalling pathway" EXACT [GOC:mah] +is_a: GO:0002753 ! cytoplasmic pattern recognition receptor signaling pathway +is_a: GO:0035872 ! nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + +[Term] +id: GO:0070424 +name: regulation of nucleotide-binding oligomerization domain containing signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add] +synonym: "regulation of NOD signaling pathway" EXACT [GOC:add] +synonym: "regulation of nucleotide-binding oligomerization domain containing signalling pathway" EXACT [GOC:mah] +is_a: GO:0062207 ! regulation of pattern recognition receptor signaling pathway +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway +relationship: regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway + +[Term] +id: GO:0070425 +name: negative regulation of nucleotide-binding oligomerization domain containing signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add] +synonym: "negative regulation of NOD signaling pathway" EXACT [GOC:add] +synonym: "negative regulation of nucleotide-binding oligomerization domain containing signalling pathway" EXACT [GOC:mah] +is_a: GO:0070424 ! regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway +relationship: negatively_regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway + +[Term] +id: GO:0070426 +name: positive regulation of nucleotide-binding oligomerization domain containing signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway." [GOC:add] +synonym: "positive regulation of NOD signaling pathway" EXACT [GOC:add] +synonym: "positive regulation of nucleotide-binding oligomerization domain containing signalling pathway" EXACT [GOC:mah] +is_a: GO:0062208 ! positive regulation of pattern recognition receptor signaling pathway +is_a: GO:0070424 ! regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway +relationship: positively_regulates GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway + +[Term] +id: GO:0070427 +name: nucleotide-binding oligomerization domain containing 1 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1)." [GOC:add, PMID:17944960, PMID:18585455] +synonym: "NOD1 signaling pathway" EXACT [GOC:add] +synonym: "nucleotide-binding oligomerization domain containing 1 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway + +[Term] +id: GO:0070428 +name: regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add] +synonym: "regulation of NOD1 signaling pathway" EXACT [GOC:add] +synonym: "regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070424 ! regulation of nucleotide-binding oligomerization domain containing signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway +relationship: regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway + +[Term] +id: GO:0070429 +name: negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add] +synonym: "negative regulation of NOD1 signaling pathway" EXACT [GOC:add] +synonym: "negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070425 ! negative regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:0070428 ! regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway +relationship: negatively_regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway + +[Term] +id: GO:0070430 +name: positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway." [GOC:add] +synonym: "positive regulation of NOD1 signaling pathway" EXACT [GOC:add] +synonym: "positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070426 ! positive regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:0070428 ! regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway +relationship: positively_regulates GO:0070427 ! nucleotide-binding oligomerization domain containing 1 signaling pathway + +[Term] +id: GO:0070431 +name: nucleotide-binding oligomerization domain containing 2 signaling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2)." [GOC:add, PMID:17944960, PMID:18585455] +synonym: "NOD2 signaling pathway" EXACT [GOC:add] +synonym: "nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070423 ! nucleotide-binding oligomerization domain containing signaling pathway + +[Term] +id: GO:0070432 +name: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add] +synonym: "regulation of NOD2 signaling pathway" EXACT [GOC:add] +synonym: "regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070424 ! regulation of nucleotide-binding oligomerization domain containing signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway +relationship: regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway + +[Term] +id: GO:0070433 +name: negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add] +synonym: "negative regulation of NOD2 signaling pathway" EXACT [GOC:add] +synonym: "negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070425 ! negative regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:0070432 ! regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway +relationship: negatively_regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway + +[Term] +id: GO:0070434 +name: positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway." [GOC:add] +synonym: "positive regulation of NOD2 signaling pathway" EXACT [GOC:add] +synonym: "positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT [GOC:mah] +is_a: GO:0070426 ! positive regulation of nucleotide-binding oligomerization domain containing signaling pathway +is_a: GO:0070432 ! regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway +relationship: positively_regulates GO:0070431 ! nucleotide-binding oligomerization domain containing 2 signaling pathway + +[Term] +id: GO:0070435 +name: Shc-EGFR complex +namespace: cellular_component +def: "A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267] +synonym: "Shc-Egfr complex, EGF stimulated" NARROW [CORUM:2887] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070436 +name: Grb2-EGFR complex +namespace: cellular_component +def: "A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267] +synonym: "Grb2-Egfr complex, EGF stimulated" NARROW [CORUM:2889] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070437 +name: Grb2-Shc complex +namespace: cellular_component +def: "A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway." [GOC:mah, PMID:7798267] +synonym: "Grb2-Shc complex, EGF stimulated" NARROW [CORUM:2888] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070438 +name: obsolete mTOR-FKBP12-rapamycin complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus)." [GOC:sl, PMID:20005306, PMID:7822316] +comment: This term was made obsolete because it describes a complex with a drug bound, with the drug being exogenous to the species where the experiment takes place and where that interaction would never occur naturally. +synonym: "Fkbp1a-Frap1 complex" NARROW [CORUM:2987] +synonym: "mTOR-FKBP12-rapamycin complex" EXACT [] +is_obsolete: true + +[Term] +id: GO:0070439 +name: Mad-Max-mSin3A complex +namespace: cellular_component +def: "A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p." [PMID:7889570] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex + +[Term] +id: GO:0070440 +name: Mad-Max-mSin3B complex +namespace: cellular_component +def: "A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p." [PMID:7889570] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex + +[Term] +id: GO:0070441 +name: G-protein beta/gamma-Btk complex +namespace: cellular_component +def: "A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein." [GOC:mah, PMID:7972043] +comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'. +synonym: "G protein complex (BTK, GNG1, GNG2)" RELATED [CORUM:1615] +synonym: "G protein complex (Btk, Gng2, Gnb1)" RELATED [CORUM:3195] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0070442 +name: integrin alphaIIb-beta3 complex +namespace: cellular_component +def: "An integrin complex that comprises one alphaIIb subunit and one beta3 subunit." [PMID:12297042] +synonym: "alphaIIb-beta3 integrin complex" EXACT [] +synonym: "ITGA2B-ITGB3 complex" NARROW [CORUM:2381] +is_a: GO:0008305 ! integrin complex + +[Term] +id: GO:0070443 +name: Mad-Max complex +namespace: cellular_component +def: "A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max." [PMID:8224841] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex + +[Term] +id: GO:0070444 +name: oligodendrocyte progenitor proliferation +namespace: biological_process +def: "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system." [GOC:mah, GOC:sl, PMID:15504915] +synonym: "oligodendrocyte precursor proliferation" EXACT [GOC:mah] +is_a: GO:0061351 ! neural precursor cell proliferation +relationship: part_of GO:0042063 ! gliogenesis + +[Term] +id: GO:0070445 +name: regulation of oligodendrocyte progenitor proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] +synonym: "regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] +is_a: GO:0014013 ! regulation of gliogenesis +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070444 ! oligodendrocyte progenitor proliferation +relationship: regulates GO:0070444 ! oligodendrocyte progenitor proliferation + +[Term] +id: GO:0070446 +name: negative regulation of oligodendrocyte progenitor proliferation +namespace: biological_process +def: "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] +synonym: "negative regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] +is_a: GO:0014014 ! negative regulation of gliogenesis +is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation +is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation +relationship: negatively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation + +[Term] +id: GO:0070447 +name: positive regulation of oligodendrocyte progenitor proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] +synonym: "positive regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] +is_a: GO:0014015 ! positive regulation of gliogenesis +is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation +is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation +relationship: positively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation + +[Term] +id: GO:0070448 +name: laricitrin 5'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin." [RHEA:25633] +comment: Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267. +synonym: "CrCOMT2" RELATED [] +synonym: "flavonoid 3',5'-O-dimethyltransferase activity" RELATED [] +synonym: "S-adenosyl-L-methionine:myricetin O-methyltransferase activity" RELATED [] +xref: EC:2.1.1.267 +xref: KEGG_REACTION:R06816 +xref: MetaCyc:RXN-8452 +xref: RHEA:25633 +is_a: GO:0008171 ! O-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0070449 +name: elongin complex +namespace: cellular_component +def: "A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits." [PMID:12676794] +comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'. +synonym: "elongin (SIII) complex" EXACT [CORUM:56] +synonym: "transcription elongation factor SIII complex" EXACT [PMID:8244996] +synonym: "transcription factor B (SIII) complex" EXACT [] +is_a: GO:0008023 ! transcription elongation factor complex + +[Term] +id: GO:0070450 +name: interleukin4-interleukin-4 receptor complex +namespace: cellular_component +def: "A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule." [GOC:mah, PMID:10358772] +synonym: "IL4-IL4 receptor complex" EXACT [GOC:mah] +synonym: "IL4-IL4R-IL2RG complex" NARROW [CORUM:1515] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070451 +name: cell hair +namespace: cellular_component +def: "A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located." [PMID:11526084] +synonym: "imaginal disc-derived wing hair" NARROW [GOC:mah] +synonym: "non-sensory hair" EXACT [GOC:bf] +xref: Wikipedia:Membrane_nanotube +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0070452 +name: positive regulation of ergosterol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol." [GOC:mah] +synonym: "activation of ergosterol biosynthetic process" NARROW [] +synonym: "positive regulation of ergosterol anabolism" EXACT [] +synonym: "positive regulation of ergosterol biosynthesis" EXACT [] +synonym: "positive regulation of ergosterol formation" EXACT [] +synonym: "positive regulation of ergosterol synthesis" EXACT [] +synonym: "stimulation of ergosterol biosynthetic process" NARROW [] +synonym: "up regulation of ergosterol biosynthetic process" EXACT [] +synonym: "up-regulation of ergosterol biosynthetic process" EXACT [] +synonym: "upregulation of ergosterol biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0032443 ! regulation of ergosterol biosynthetic process +is_a: GO:0106120 ! positive regulation of sterol biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006696 ! ergosterol biosynthetic process +relationship: positively_regulates GO:0006696 ! ergosterol biosynthetic process + +[Term] +id: GO:0070453 +name: regulation of heme biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme." [GOC:mah] +synonym: "regulation of haem biosynthesis" EXACT [GOC:mah] +synonym: "regulation of haem biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of heme anabolism" EXACT [GOC:mah] +synonym: "regulation of heme biosynthesis" EXACT [GOC:mah] +synonym: "regulation of heme formation" EXACT [GOC:mah] +synonym: "regulation of heme synthesis" EXACT [GOC:mah] +is_a: GO:0051193 ! regulation of cofactor metabolic process +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006783 ! heme biosynthetic process +relationship: regulates GO:0006783 ! heme biosynthetic process + +[Term] +id: GO:0070454 +name: negative regulation of heme biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme." [GOC:mah] +synonym: "down regulation of heme biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of heme biosynthetic process" EXACT [GOC:mah] +synonym: "downregulation of heme biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of heme biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of haem biosynthetic process" EXACT [GOC:mah] +synonym: "negative regulation of heme anabolism" EXACT [GOC:mah] +synonym: "negative regulation of heme biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of heme formation" EXACT [GOC:mah] +synonym: "negative regulation of heme synthesis" EXACT [GOC:mah] +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:0070453 ! regulation of heme biosynthetic process +is_a: GO:1901464 ! negative regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006783 ! heme biosynthetic process +relationship: negatively_regulates GO:0006783 ! heme biosynthetic process + +[Term] +id: GO:0070455 +name: positive regulation of heme biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme." [GOC:mah] +synonym: "activation of heme biosynthetic process" NARROW [GOC:mah] +synonym: "positive regulation of haem biosynthetic process" EXACT [GOC:mah] +synonym: "positive regulation of heme anabolism" EXACT [GOC:mah] +synonym: "positive regulation of heme biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of heme formation" EXACT [GOC:mah] +synonym: "positive regulation of heme synthesis" EXACT [GOC:mah] +synonym: "stimulation of heme biosynthetic process" NARROW [GOC:mah] +synonym: "up regulation of heme biosynthetic process" EXACT [GOC:mah] +synonym: "up-regulation of heme biosynthetic process" EXACT [GOC:mah] +synonym: "upregulation of heme biosynthetic process" EXACT [GOC:mah] +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:0070453 ! regulation of heme biosynthetic process +is_a: GO:1901465 ! positive regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006783 ! heme biosynthetic process +relationship: positively_regulates GO:0006783 ! heme biosynthetic process + +[Term] +id: GO:0070456 +name: galactose-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate." [GOC:mah] +is_a: GO:0050308 ! sugar-phosphatase activity + +[Term] +id: GO:0070457 +name: D-galactose-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate." [GOC:mah, PMID:9462881] +is_a: GO:0070456 ! galactose-1-phosphate phosphatase activity + +[Term] +id: GO:0070458 +name: cellular detoxification of nitrogen compound +namespace: biological_process +def: "Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:mah] +synonym: "cellular detoxification of nitrogenous compound" EXACT [GOC:mah] +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:1990748 ! cellular detoxification +relationship: part_of GO:0033554 ! cellular response to stress + +[Term] +id: GO:0070459 +name: prolactin secretion +namespace: biological_process +def: "The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary." [GOC:mah, ISBN:0198506732] +is_a: GO:0009306 ! protein secretion +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0070460 +name: thyroid-stimulating hormone secretion +namespace: biological_process +def: "The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary." [GOC:mah, ISBN:0198506732] +synonym: "thyroid stimulating hormone secretion" EXACT [GOC:mah] +synonym: "TSH secretion" EXACT [] +is_a: GO:0030072 ! peptide hormone secretion + +[Term] +id: GO:0070461 +name: SAGA-type complex +namespace: cellular_component +def: "A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins." [GOC:mah, PMID:10637607, PMID:17337012] +synonym: "SAGA family complex" EXACT [PMID:17337012] +is_a: GO:0000123 ! histone acetyltransferase complex + +[Term] +id: GO:0070462 +name: plus-end specific microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from the plus end of a microtubule." [GOC:krc, PMID:16906145, PMID:16906148] +is_a: GO:0007019 ! microtubule depolymerization + +[Term] +id: GO:0070463 +name: tubulin-dependent ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate." [GOC:mah, PMID:16906148] +synonym: "tubulin-activated ATPase activity" EXACT [] +is_a: GO:0016887 ! ATPase activity + +[Term] +id: GO:0070464 +name: alphav-beta3 integrin-collagen alpha3(VI) complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen." [PMID:8387021] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070465 +name: alpha1-beta1 integrin-alpha3(VI) complex +namespace: cellular_component +def: "A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain." [PMID:8387021] +synonym: "ITGA1-ITGB1-COL6A3 complex" NARROW [CORUM:2434] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070466 +name: alpha2-beta1 integrin-alpha3(VI) complex +namespace: cellular_component +def: "A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain." [PMID:8387021] +synonym: "ITGA2-ITGB1-COL6A3 complex" NARROW [CORUM:2431] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070467 +name: RC-1 DNA recombination complex +namespace: cellular_component +def: "A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA." [PMID:8392064, PMID:8670910] +synonym: "DNA recombination complex RC-1" EXACT [GOC:mah] +synonym: "RC-1 complex (recombination complex 1)" EXACT [CORUM:364] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070468 +name: dentin secretion +namespace: biological_process +def: "The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin." [GOC:mah, PMID:12856968] +synonym: "dentine secretion" EXACT [GOC:mah] +synonym: "predentin secretion" EXACT [] +is_a: GO:0070278 ! extracellular matrix constituent secretion +relationship: part_of GO:0042475 ! odontogenesis of dentin-containing tooth + +[Term] +id: GO:0070469 +name: respirasome +namespace: cellular_component +def: "The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient." [GOC:ecd, GOC:mah, ISBN:0198547684, Wikipedia:Respirasome] +synonym: "membrane electron transport chain" EXACT [GOC:mah] +synonym: "respiratory chain" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016020 ! membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12846 xsd:anyURI + +[Term] +id: GO:0070470 +name: plasma membrane respirasome +namespace: cellular_component +def: "A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient." [GOC:curators, GOC:imk, GOC:mah, ISBN:0198547684] +synonym: "plasma membrane electron transport chain" EXACT [GOC:mah] +synonym: "plasma membrane respiratory chain" EXACT [] +is_a: GO:0070469 ! respirasome +relationship: part_of GO:0005886 ! plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12846 xsd:anyURI + +[Term] +id: GO:0070471 +name: uterine smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth." [GOC:sl] +synonym: "myometrial contraction" EXACT [GOC:sl] +synonym: "myometrial smooth muscle contraction" EXACT [GOC:sl] +synonym: "myometrium contraction" EXACT [GOC:sl] +is_a: GO:0006939 ! smooth muscle contraction + +[Term] +id: GO:0070472 +name: regulation of uterine smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction." [GOC:go_curators] +synonym: "regulation of myometrial contraction" EXACT [GOC:sl] +synonym: "regulation of myometrial smooth muscle contraction" EXACT [GOC:sl] +synonym: "regulation of myometrium contraction" EXACT [GOC:sl] +is_a: GO:0006940 ! regulation of smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070471 ! uterine smooth muscle contraction +relationship: regulates GO:0070471 ! uterine smooth muscle contraction + +[Term] +id: GO:0070473 +name: negative regulation of uterine smooth muscle contraction +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction." [GOC:go_curators] +synonym: "down regulation of uterine smooth muscle contraction" EXACT [GOC:mah] +synonym: "down-regulation of uterine smooth muscle contraction" EXACT [GOC:mah] +synonym: "downregulation of uterine smooth muscle contraction" EXACT [GOC:mah] +synonym: "inhibition of uterine smooth muscle contraction" NARROW [GOC:mah] +synonym: "negative regulation of myometrial contraction" EXACT [GOC:sl] +synonym: "negative regulation of myometrial smooth muscle contraction" EXACT [GOC:sl] +synonym: "negative regulation of myometrium contraction" EXACT [GOC:sl] +synonym: "uterine smooth muscle relaxation" RELATED [GOC:mah] +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +is_a: GO:0070472 ! regulation of uterine smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070471 ! uterine smooth muscle contraction +relationship: negatively_regulates GO:0070471 ! uterine smooth muscle contraction + +[Term] +id: GO:0070474 +name: positive regulation of uterine smooth muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of uterine smooth muscle contraction." [GOC:go_curators] +synonym: "activation of uterine smooth muscle contraction" NARROW [GOC:mah] +synonym: "positive regulation of myometrial contraction" EXACT [GOC:sl] +synonym: "positive regulation of myometrial smooth muscle contraction" EXACT [GOC:sl] +synonym: "positive regulation of myometrium contraction" EXACT [GOC:sl] +synonym: "stimulation of uterine smooth muscle contraction" NARROW [GOC:mah] +synonym: "up regulation of uterine smooth muscle contraction" EXACT [GOC:mah] +synonym: "up-regulation of uterine smooth muscle contraction" EXACT [GOC:mah] +synonym: "upregulation of uterine smooth muscle contraction" EXACT [GOC:mah] +is_a: GO:0045987 ! positive regulation of smooth muscle contraction +is_a: GO:0070472 ! regulation of uterine smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070471 ! uterine smooth muscle contraction +relationship: positively_regulates GO:0070471 ! uterine smooth muscle contraction + +[Term] +id: GO:0070475 +name: rRNA base methylation +namespace: biological_process +def: "The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule." [GOC:mah] +is_a: GO:0031167 ! rRNA methylation + +[Term] +id: GO:0070476 +name: rRNA (guanine-N7)-methylation +namespace: biological_process +def: "The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule." [GOC:mah] +is_a: GO:0036265 ! RNA (guanine-N7)-methylation +is_a: GO:0070475 ! rRNA base methylation + +[Term] +id: GO:0070477 +name: endospore core +namespace: cellular_component +def: "An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive." [GOC:mah, PMID:15035041, PMID:18035610] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular + +[Term] +id: GO:0070478 +name: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction." [PMID:12769863] +synonym: "3'-5' NMD" EXACT [GOC:jp] +synonym: "3'-5' nonsense-mediated decay" EXACT [GOC:jp] +synonym: "3'-5' nonsense-mediated mRNA decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +is_a: GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +is_a: GO:0034427 ! nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' + +[Term] +id: GO:0070479 +name: nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction." [PMID:18554525] +synonym: "5'-3' NMD" EXACT [GOC:jp] +synonym: "5'-3' nonsense-mediated decay" EXACT [GOC:jp] +synonym: "5'-3' nonsense-mediated mRNA decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay" EXACT [GOC:mah] +is_a: GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +is_a: GO:0034428 ! nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' +is_a: GO:0070480 ! exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay + +[Term] +id: GO:0070480 +name: exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay." [GOC:jp] +synonym: "exonucleolytic nuclear-transcribed mRNA breakdown involved in deadenylation-independent decay" EXACT [GOC:mah] +synonym: "exonucleolytic nuclear-transcribed mRNA catabolism involved in deadenylation-independent decay" EXACT [GOC:mah] +synonym: "exonucleolytic nuclear-transcribed mRNA degradation involved in deadenylation-independent decay" EXACT [GOC:mah] +is_a: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: GO:0000291 ! nuclear-transcribed mRNA catabolic process, exonucleolytic +intersection_of: part_of GO:0031086 ! nuclear-transcribed mRNA catabolic process, deadenylation-independent decay +relationship: part_of GO:0031086 ! nuclear-transcribed mRNA catabolic process, deadenylation-independent decay + +[Term] +id: GO:0070481 +name: nuclear-transcribed mRNA catabolic process, non-stop decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon." [PMID:11910110] +synonym: "non-stop decay" EXACT [GOC:jp] +synonym: "non-stop mRNA decay" EXACT [GOC:jp] +synonym: "nonstop mRNA decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA breakdown, non-stop decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA catabolism, non-stop decay" EXACT [GOC:mah] +synonym: "nuclear-transcribed mRNA degradation, non-stop decay" EXACT [GOC:mah] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process + +[Term] +id: GO:0070482 +name: response to oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:BHF, GOC:mah] +is_a: GO:0009628 ! response to abiotic stimulus + +[Term] +id: GO:0070483 +name: detection of hypoxia +namespace: biological_process +def: "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:BHF, GOC:mah] +synonym: "detection of reduced oxygen levels" EXACT [GOC:vk] +is_a: GO:0001666 ! response to hypoxia +is_a: GO:0003032 ! detection of oxygen + +[Term] +id: GO:0070484 +name: dehydro-D-arabinono-1,4-lactone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one." [GOC:cjk, GOC:mah] +synonym: "dehydro-D-arabinono-1,4-lactone metabolism" EXACT [GOC:mah] +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901334 ! lactone metabolic process + +[Term] +id: GO:0070485 +name: dehydro-D-arabinono-1,4-lactone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one." [GOC:cjk, GOC:mah] +synonym: "dehydro-D-arabinono-1,4-lactone anabolism" EXACT [GOC:mah] +synonym: "dehydro-D-arabinono-1,4-lactone biosynthesis" EXACT [GOC:mah] +synonym: "dehydro-D-arabinono-1,4-lactone formation" EXACT [GOC:mah] +synonym: "dehydro-D-arabinono-1,4-lactone synthesis" EXACT [GOC:mah] +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0070484 ! dehydro-D-arabinono-1,4-lactone metabolic process +is_a: GO:1901336 ! lactone biosynthetic process + +[Term] +id: GO:0070486 +name: leukocyte aggregation +namespace: biological_process +def: "The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules." [GOC:sl, PMID:12972508] +synonym: "immune cell aggregation" EXACT [CL:0000738] +synonym: "leucocyte aggregation" EXACT [CL:0000738, GOC:sl] +synonym: "white blood cell aggregation" EXACT [CL:0000738, GOC:sl] +synonym: "white corpuscle aggregation" EXACT [GOC:sl] +is_a: GO:0007159 ! leukocyte cell-cell adhesion + +[Term] +id: GO:0070487 +name: monocyte aggregation +namespace: biological_process +def: "The adhesion of one monocyte to one or more other monocytes via adhesion molecules." [GOC:sl, PMID:12972508] +synonym: "mononuclear phagocyte aggregation" EXACT [GOC:sl] +is_a: GO:0070486 ! leukocyte aggregation + +[Term] +id: GO:0070488 +name: neutrophil aggregation +namespace: biological_process +def: "The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules." [GOC:sl, PMID:12972508] +synonym: "neutrocyte aggregation" EXACT [CL:0000775, GOC:mah] +synonym: "neutrophil leucocyte aggregation" EXACT [CL:0000775, GOC:mah] +synonym: "neutrophil leukocyte aggregation" EXACT [CL:0000775, GOC:mah] +synonym: "neutrophilic leucocyte aggregation" EXACT [CL:0000775, GOC:mah] +synonym: "neutrophilic leukocyte aggregation" EXACT [CL:0000775, GOC:mah] +is_a: GO:0070486 ! leukocyte aggregation + +[Term] +id: GO:0070489 +name: T cell aggregation +namespace: biological_process +def: "The adhesion of one T cell to one or more other T cells via adhesion molecules." [GOC:sl, PMID:12972508] +synonym: "T lymphocyte aggregation" EXACT [CL:0000084, GOC:sl] +synonym: "T-cell aggregation" EXACT [CL:0000084, GOC:mah] +synonym: "T-lymphocyte aggregation" EXACT [CL:0000084, GOC:mah] +is_a: GO:0071593 ! lymphocyte aggregation + +[Term] +id: GO:0070490 +name: protein pupylation +namespace: biological_process +def: "The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein." [PMID:18980670] +synonym: "Pup-protein conjugation" EXACT [GOC:mah] +synonym: "pupylation" EXACT [GOC:mah] +is_a: GO:0018205 ! peptidyl-lysine modification +is_a: GO:0032446 ! protein modification by small protein conjugation + +[Term] +id: GO:0070491 +name: repressing transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription." [GOC:mah, GOC:txnOH] +is_a: GO:0140297 ! DNA-binding transcription factor binding + +[Term] +id: GO:0070492 +name: oligosaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages." [GOC:mah] +is_a: GO:0030246 ! carbohydrate binding + +[Term] +id: GO:0070493 +name: thrombin-activated receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands." [GOC:mah, PMID:1672265] +synonym: "thrombin receptor signaling pathway" EXACT [] +synonym: "thrombin receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0070494 +name: regulation of thrombin-activated receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "regulation of thrombin receptor signaling pathway" EXACT [] +synonym: "regulation of thrombin receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070493 ! thrombin-activated receptor signaling pathway +relationship: regulates GO:0070493 ! thrombin-activated receptor signaling pathway + +[Term] +id: GO:0070495 +name: negative regulation of thrombin-activated receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "negative regulation of thrombin receptor signaling pathway" EXACT [] +synonym: "negative regulation of thrombin receptor signalling pathway" RELATED [GOC:mah] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0070494 ! regulation of thrombin-activated receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070493 ! thrombin-activated receptor signaling pathway +relationship: negatively_regulates GO:0070493 ! thrombin-activated receptor signaling pathway + +[Term] +id: GO:0070496 +name: positive regulation of thrombin-activated receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "positive regulation of thrombin receptor signaling pathway" EXACT [] +synonym: "positive regulation of thrombin receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0070494 ! regulation of thrombin-activated receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070493 ! thrombin-activated receptor signaling pathway +relationship: positively_regulates GO:0070493 ! thrombin-activated receptor signaling pathway + +[Term] +id: GO:0070497 +name: 6-carboxy-5,6,7,8-tetrahydropterin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+." [GOC:imk, MetaCyc:RXN0-5507, PMID:19231875] +xref: EC:4.1.2.50 +xref: MetaCyc:RXN0-5507 +xref: RHEA:27966 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0070498 +name: interleukin-1-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mah, GOC:signaling] +synonym: "IL-1 alpha-mediated signaling pathway" NARROW [GOC:add] +synonym: "IL-1 beta-mediated signaling pathway" NARROW [GOC:add] +synonym: "IL-1-mediated signaling pathway" EXACT [GOC:mah] +synonym: "interleukin-1 alpha-mediated signaling pathway" NARROW [GOC:add] +synonym: "interleukin-1 beta-mediated signaling pathway" NARROW [GOC:add] +synonym: "interleukin-1-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0071347 ! cellular response to interleukin-1 + +[Term] +id: GO:0070499 +name: exosporium assembly +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore." [GOC:mah] +synonym: "exosporium formation" EXACT [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0045229 ! external encapsulating structure organization + +[Term] +id: GO:0070500 +name: poly-gamma-glutamate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds." [GOC:mah, PMID:16689787] +synonym: "poly-gamma-glutamate metabolism" EXACT [GOC:mah] +is_a: GO:0044260 ! cellular macromolecule metabolic process + +[Term] +id: GO:0070501 +name: poly-gamma-glutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds." [GOC:mah, PMID:16689787] +synonym: "poly-gamma-glutamate anabolism" EXACT [GOC:mah] +synonym: "poly-gamma-glutamate biosynthesis" EXACT [GOC:mah] +synonym: "poly-gamma-glutamate formation" EXACT [GOC:mah] +synonym: "poly-gamma-glutamate synthesis" EXACT [GOC:mah] +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0070500 ! poly-gamma-glutamate metabolic process + +[Term] +id: GO:0070502 +name: capsule poly-gamma-glutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule." [GOC:mah, PMID:16689787] +synonym: "capsular poly-gamma-glutamate biosynthetic process" EXACT [GOC:mah] +synonym: "capsule poly-gamma-glutamate anabolism" EXACT [GOC:mah] +synonym: "capsule poly-gamma-glutamate biosynthesis" EXACT [GOC:mah] +synonym: "capsule poly-gamma-glutamate formation" EXACT [GOC:mah] +synonym: "capsule poly-gamma-glutamate synthesis" EXACT [GOC:mah] +is_a: GO:0045230 ! capsule organization +is_a: GO:0070501 ! poly-gamma-glutamate biosynthetic process + +[Term] +id: GO:0070503 +name: selenium-containing prosthetic group metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments." [GOC:dh, GOC:mah] +synonym: "selenium-containing prosthetic group metabolism" EXACT [GOC:mah] +is_a: GO:0001887 ! selenium compound metabolic process +is_a: GO:0051189 ! prosthetic group metabolic process + +[Term] +id: GO:0070504 +name: selenium-containing prosthetic group biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments." [GOC:dh, GOC:mah] +synonym: "selenium-containing prosthetic group anabolism" EXACT [GOC:mah] +synonym: "selenium-containing prosthetic group biosynthesis" EXACT [GOC:mah] +synonym: "selenium-containing prosthetic group formation" EXACT [GOC:mah] +synonym: "selenium-containing prosthetic group synthesis" EXACT [GOC:mah] +is_a: GO:0051191 ! prosthetic group biosynthetic process +is_a: GO:0070503 ! selenium-containing prosthetic group metabolic process + +[Term] +id: GO:0070505 +name: pollen coat +namespace: cellular_component +def: "A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma." [GOC:mah, GOC:rph, PMID:12930826, PMID:15012271] +synonym: "pollenkitt" EXACT [PMID:15012271] +synonym: "tryphine" EXACT [PMID:15012271] +is_a: GO:0031012 ! extracellular matrix + +[Term] +id: GO:0070506 +name: high-density lipoprotein particle receptor activity +namespace: molecular_function +def: "Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis." [GOC:bf, GOC:BHF, GOC:rl, PMID:9211901] +synonym: "HDL receptor" EXACT [GOC:rl] +synonym: "high-density lipoprotein receptor activity" EXACT [GOC:dph] +is_a: GO:0030228 ! lipoprotein particle receptor activity +relationship: has_part GO:0008035 ! high-density lipoprotein particle binding + +[Term] +id: GO:0070507 +name: regulation of microtubule cytoskeleton organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] +synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah] +synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb] +is_a: GO:0032886 ! regulation of microtubule-based process +is_a: GO:0051493 ! regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization +relationship: regulates GO:0000226 ! microtubule cytoskeleton organization + +[Term] +id: GO:0070508 +name: cholesterol import +namespace: biological_process +def: "The directed movement of cholesterol into a cell or organelle." [GOC:BHF, GOC:rl] +synonym: "cholesterol uptake" EXACT [GOC:rl] +is_a: GO:0030301 ! cholesterol transport +is_a: GO:0035376 ! sterol import + +[Term] +id: GO:0070509 +name: calcium ion import +namespace: biological_process +def: "The directed movement of calcium ions into a cell or organelle." [GOC:mah] +synonym: "calcium ion uptake" EXACT [GOC:mah] +synonym: "transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0006816 ! calcium ion transport + +[Term] +id: GO:0070510 +name: regulation of histone H4-K20 methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4." [GOC:mah] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034770 ! histone H4-K20 methylation +relationship: regulates GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0070511 +name: negative regulation of histone H4-K20 methylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4." [GOC:mah] +synonym: "down regulation of histone H4-K20 methylation" EXACT [GOC:mah] +synonym: "down-regulation of histone H4-K20 methylation" EXACT [GOC:mah] +synonym: "downregulation of histone H4-K20 methylation" EXACT [GOC:mah] +synonym: "inhibition of histone H4-K20 methylation" NARROW [GOC:mah] +is_a: GO:0031061 ! negative regulation of histone methylation +is_a: GO:0070510 ! regulation of histone H4-K20 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034770 ! histone H4-K20 methylation +relationship: negatively_regulates GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0070512 +name: positive regulation of histone H4-K20 methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4." [GOC:mah] +synonym: "activation of histone H4-K20 methylation" NARROW [GOC:mah] +synonym: "stimulation of histone H4-K20 methylation" NARROW [GOC:mah] +synonym: "up regulation of histone H4-K20 methylation" EXACT [GOC:mah] +synonym: "up-regulation of histone H4-K20 methylation" EXACT [GOC:mah] +synonym: "upregulation of histone H4-K20 methylation" EXACT [GOC:mah] +is_a: GO:0031062 ! positive regulation of histone methylation +is_a: GO:0070510 ! regulation of histone H4-K20 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034770 ! histone H4-K20 methylation +relationship: positively_regulates GO:0034770 ! histone H4-K20 methylation + +[Term] +id: GO:0070513 +name: death domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB." [GOC:BHF, GOC:rl, InterPro:IPR000488, Pfam:PF00531] +comment: For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'. +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0070514 +name: SRF-myogenin-E12 complex +namespace: cellular_component +def: "A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes." [PMID:8617811] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0070515 +name: alphaIIb-beta3 integrin-talin complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin." [PMID:8663236] +synonym: "ITGA2b-ITGB3-TLN1 complex" NARROW [CORUM:2378] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070516 +name: CAK-ERCC2 complex +namespace: cellular_component +def: "A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2." [PMID:8692841, PMID:8692842] +synonym: "cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex" EXACT [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070517 +name: DNA replication factor C core complex +namespace: cellular_component +def: "A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37." [PMID:8692848, PMID:9228079, PMID:9582326] +synonym: "RFC core complex" EXACT [CORUM:278] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043599 ! nuclear DNA replication factor C complex + +[Term] +id: GO:0070518 +name: alpha4-beta1 integrin-CD53 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family." [PMID:8757325] +synonym: "ITGA4-ITGB1-CD53 complex" NARROW [CORUM:2420] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070519 +name: alpha4-beta1 integrin-CD63 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family." [PMID:8757325] +synonym: "ITGA4-ITGB1-CD63 complex" NARROW [CORUM:2424] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070520 +name: alpha4-beta1 integrin-CD81 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family." [PMID:10229664, PMID:8757325] +synonym: "ITGA4-ITGB1-CD81 complex" NARROW [CORUM:2419] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070521 +name: alpha4-beta1 integrin-CD82 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family." [PMID:8757325] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070522 +name: ERCC4-ERCC1 complex +namespace: cellular_component +def: "A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae." [PMID:14734547] +comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. +synonym: "Rad1-Rad10 complex" EXACT [GOC:mah] +synonym: "XPF-ERCC1 complex" EXACT [PMID:14734547] +is_a: GO:0000109 ! nucleotide-excision repair complex + +[Term] +id: GO:0070523 +name: 11-beta-hydroxysteroid dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+." [PMID:15761036] +is_a: GO:0003845 ! 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity + +[Term] +id: GO:0070524 +name: 11-beta-hydroxysteroid dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+." [EC:1.1.1.146] +synonym: "11beta-hydroxysteroid:NADP+ 11-oxidoreductase" EXACT [EC:1.1.1.146] +synonym: "beta-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.146] +synonym: "corticosteroid 11-beta-dehydrogenase activity" EXACT [EC:1.1.1.146] +xref: EC:1.1.1.146 +xref: MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN +is_a: GO:0003845 ! 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity + +[Term] +id: GO:0070525 +name: tRNA threonylcarbamoyladenosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules." [GOC:imk, GOC:mah, PMID:19287007] +synonym: "t6A metabolic process" EXACT [PMID:19287007] +synonym: "t6A metabolism" EXACT [PMID:19287007] +synonym: "threonylcarbamoyladenosine metabolism" EXACT [GOC:MAH] +is_a: GO:0016070 ! RNA metabolic process + +[Term] +id: GO:0070527 +name: platelet aggregation +namespace: biological_process +def: "The adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:BHF, GOC:vk] +synonym: "blood platelet aggregation" EXACT [CL:0000233] +synonym: "thrombocyte aggregation" RELATED [CL:0000233] +is_a: GO:0034109 ! homotypic cell-cell adhesion +relationship: part_of GO:0030168 ! platelet activation + +[Term] +id: GO:0070528 +name: protein kinase C signaling +namespace: biological_process +def: "A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound." [GOC:BHF, GOC:mah] +synonym: "PKC signal transduction" EXACT [GOC:signaling] +synonym: "PKC signaling cascade" RELATED [GOC:mah] +synonym: "protein kinase C signal transduction" EXACT [GOC:signaling] +synonym: "protein kinase C signaling cascade" RELATED [GOC:signaling] +synonym: "protein kinase C signalling cascade" RELATED [GOC:mah] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0070529 +name: L-tryptophan aminotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid." [GOC:mah] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0070530 +name: K63-linked polyubiquitin modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein." [GOC:mah, PMID:15556404, PMID:17525341] +is_a: GO:0031593 ! polyubiquitin modification-dependent protein binding + +[Term] +id: GO:0070531 +name: BRCA1-A complex +namespace: cellular_component +def: "A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites." [GOC:mah, PMID:19261749] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070532 +name: BRCA1-B complex +namespace: cellular_component +def: "A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites." [GOC:mah, PMID:16391231] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070533 +name: BRCA1-C complex +namespace: cellular_component +def: "A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint." [GOC:mah, PMID:15485915, PMID:16391231] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070534 +name: protein K63-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair." [GOC:mah, PMID:15556404] +synonym: "protein K63-linked polyubiquitination" EXACT [GOC:mah] +is_a: GO:0000209 ! protein polyubiquitination + +[Term] +id: GO:0070535 +name: histone H2A K63-linked ubiquitination +namespace: biological_process +def: "A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX." [GOC:mah, PMID:18430235] +is_a: GO:0033522 ! histone H2A ubiquitination +is_a: GO:0070534 ! protein K63-linked ubiquitination + +[Term] +id: GO:0070536 +name: protein K63-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein." [GOC:mah, PMID:19202061, PMID:19214193] +is_a: GO:0016579 ! protein deubiquitination + +[Term] +id: GO:0070537 +name: histone H2A K63-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX." [GOC:mah, PMID:19202061, PMID:19214193] +is_a: GO:0016578 ! histone deubiquitination +is_a: GO:0070536 ! protein K63-linked deubiquitination + +[Term] +id: GO:0070538 +name: oleic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid." [GOC:lp, GOC:mah] +is_a: GO:0036041 ! long-chain fatty acid binding + +[Term] +id: GO:0070539 +name: linoleic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid." [GOC:lp, GOC:mah] +is_a: GO:0036041 ! long-chain fatty acid binding + +[Term] +id: GO:0070540 +name: stearic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with stearic acid, the 18-carbon saturated fatty acid octadecanoic acid." [GOC:lp, GOC:mah] +is_a: GO:0036041 ! long-chain fatty acid binding + +[Term] +id: GO:0070541 +name: response to platinum ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus." [GOC:sl] +synonym: "response to platinum" EXACT [GOC:mah] +is_a: GO:0010038 ! response to metal ion + +[Term] +id: GO:0070542 +name: response to fatty acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." [GOC:lp] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0070543 +name: response to linoleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus." [GOC:lp] +synonym: "response to linoleate" EXACT [GOC:mah] +is_a: GO:0070542 ! response to fatty acid + +[Term] +id: GO:0070544 +name: histone H3-K36 demethylation +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone." [GOC:sart, PMID:19061644] +synonym: "H3K36 demethylation" RELATED [] +is_a: GO:0070076 ! histone lysine demethylation + +[Term] +id: GO:0070545 +name: PeBoW complex +namespace: cellular_component +def: "A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively." [GOC:ab, GOC:mah, PMID:16043514, PMID:17353269] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0030686 ! 90S preribosome + +[Term] +id: GO:0070546 +name: L-phenylalanine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid." [GOC:mah] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0070547 +name: L-tyrosine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid." [GOC:mah] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0070548 +name: L-glutamine aminotransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid." [GOC:mah] +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0070549 +name: negative regulation of translation involved in RNA interference +namespace: biological_process +def: "A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA." [GOC:mah, PMID:18771919] +synonym: "down regulation of translation involved in RNA interference" EXACT [GOC:mah] +synonym: "down-regulation of translation involved in RNA interference" EXACT [GOC:mah] +synonym: "downregulation of translation involved in RNA interference" EXACT [GOC:mah] +synonym: "inhibition of translation involved in RNA interference" NARROW [GOC:mah] +synonym: "RNA interference, negative regulation of translation" EXACT [GOC:mah] +is_a: GO:0040033 ! negative regulation of translation, ncRNA-mediated +intersection_of: GO:0017148 ! negative regulation of translation +intersection_of: part_of GO:0016246 ! RNA interference +relationship: part_of GO:0016246 ! RNA interference + +[Term] +id: GO:0070550 +name: rDNA condensation +namespace: biological_process +def: "The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase." [GOC:dgf, PMID:10811823, PMID:15137940] +synonym: "rDNA packaging" EXACT [] +is_a: GO:0006323 ! DNA packaging +relationship: part_of GO:0030261 ! chromosome condensation + +[Term] +id: GO:0070551 +name: endoribonuclease activity, cleaving siRNA-paired mRNA +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters." [GOC:mah, PMID:15105377] +synonym: "argonaute endoribonuclease activity" RELATED [GOC:mah] +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters + +[Term] +id: GO:0070552 +name: BRISC complex +namespace: cellular_component +def: "A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains." [GOC:mah, PMID:19214193] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070553 +name: nicotinic acid receptor activity +namespace: molecular_function +def: "Combining with nicotinic acid to initiate a change in cell activity." [GOC:mah, PMID:12522134] +synonym: "niacin receptor activity" EXACT [CHEBI:15940, GOC:mah] +is_a: GO:0004930 ! G protein-coupled receptor activity + +[Term] +id: GO:0070554 +name: synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex +namespace: cellular_component +def: "A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof)." [PMID:8824312] +synonym: "SNARE complex (Stx3, Snap25, Vamp2, Cplx1)" NARROW [CORUM:842] +synonym: "Stx3-Snap25-Vamp2-Cplx1 complex" NARROW [CORUM:842] +is_a: GO:0031201 ! SNARE complex + +[Term] +id: GO:0070555 +name: response to interleukin-1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus." [GOC:BHF, GOC:mah] +synonym: "response to IL-1" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine + +[Term] +id: GO:0070556 +name: TAF4B-containing transcription factor TFIID complex +namespace: cellular_component +def: "A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4." [GOC:mah, PMID:8858156] +synonym: "TFIID complex, B-cell specific" RELATED [CORUM:485] +is_a: GO:0005669 ! transcription factor TFIID complex + +[Term] +id: GO:0070557 +name: PCNA-p21 complex +namespace: cellular_component +def: "A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication." [GOC:mah, PMID:7911228, PMID:7915843] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0070558 +name: alphaM-beta2 integrin-CD63 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family." [PMID:8871662] +synonym: "ITGAM-ITGB2-CD63 complex" NARROW [CORUM:2153] +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0070559 +name: lysosomal multienzyme complex +namespace: cellular_component +def: "A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism." [GOC:mah, PMID:8910459] +synonym: "GALNS-lysosomal hydrolase 1.27 MDa complex" NARROW [CORUM:1379] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005764 ! lysosome + +[Term] +id: GO:0070560 +name: protein secretion by platelet +namespace: biological_process +def: "The regulated release of proteins by a platelet or group of platelets." [GOC:BHF, GOC:mah] +is_a: GO:0009306 ! protein secretion +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0002576 ! platelet degranulation +created_by: mah +creation_date: 2009-04-09T02:38:05Z + +[Term] +id: GO:0070561 +name: vitamin D receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands." [GOC:BHF, GOC:mah, PMID:12637589] +synonym: "calcitriol signaling pathway" NARROW [GOC:bf] +synonym: "VDR signaling pathway" EXACT [PMID:12637589] +synonym: "vitamin D receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0030522 ! intracellular receptor signaling pathway +relationship: part_of GO:0071305 ! cellular response to vitamin D +created_by: mah +creation_date: 2009-04-14T01:43:59Z + +[Term] +id: GO:0070562 +name: regulation of vitamin D receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity." [GOC:BHF, GOC:mah] +synonym: "regulation of VDR signaling pathway" EXACT [PMID:12637589] +synonym: "regulation of vitamin D receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0032107 ! regulation of response to nutrient levels +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070561 ! vitamin D receptor signaling pathway +relationship: regulates GO:0070561 ! vitamin D receptor signaling pathway +created_by: mah +creation_date: 2009-04-14T01:46:03Z + +[Term] +id: GO:0070563 +name: negative regulation of vitamin D receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity." [GOC:BHF, GOC:mah] +synonym: "down regulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +synonym: "down-regulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +synonym: "downregulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +synonym: "inhibition of vitamin D receptor signaling pathway" NARROW [GOC:mah] +synonym: "negative regulation of VDR signaling pathway" EXACT [GOC:mah] +synonym: "negative regulation of VDR signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation vitamin D receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:0070562 ! regulation of vitamin D receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070561 ! vitamin D receptor signaling pathway +relationship: negatively_regulates GO:0070561 ! vitamin D receptor signaling pathway +created_by: mah +creation_date: 2009-04-14T01:59:21Z + +[Term] +id: GO:0070564 +name: positive regulation of vitamin D receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity." [GOC:BHF, GOC:mah] +synonym: "activation of vitamin D receptor signaling pathway" NARROW [GOC:mah] +synonym: "positive regulation of VDR signaling pathway" EXACT [GOC:mah] +synonym: "positive regulation of vitamin D receptor signalling pathway" EXACT [GOC:mah] +synonym: "stimulation of vitamin D receptor signaling pathway" NARROW [GOC:mah] +synonym: "up regulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +synonym: "up-regulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +synonym: "upregulation of vitamin D receptor signaling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:0070562 ! regulation of vitamin D receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070561 ! vitamin D receptor signaling pathway +relationship: positively_regulates GO:0070561 ! vitamin D receptor signaling pathway +created_by: mah +creation_date: 2009-04-14T02:02:54Z + +[Term] +id: GO:0070565 +name: telomere-telomerase complex +namespace: cellular_component +def: "A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome." [GOC:pde, PMID:19179534] +comment: Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome. +is_a: GO:0032993 ! protein-DNA complex +relationship: part_of GO:0000781 ! chromosome, telomeric region +created_by: mah +creation_date: 2009-04-14T03:07:50Z + +[Term] +id: GO:0070566 +name: adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an adenylyl group to an acceptor." [GOC:mah] +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: mah +creation_date: 2009-04-15T11:04:22Z + +[Term] +id: GO:0070567 +name: cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a cytidylyl group to an acceptor." [GOC:mah] +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: mah +creation_date: 2009-04-15T11:05:22Z + +[Term] +id: GO:0070568 +name: guanylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a guanylyl group to an acceptor." [GOC:mah] +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: mah +creation_date: 2009-04-15T11:05:47Z + +[Term] +id: GO:0070569 +name: uridylyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an uridylyl group to an acceptor." [GOC:mah] +synonym: "uridyl transferase activity" EXACT [] +synonym: "uridyltransferase activity" EXACT [] +is_a: GO:0016779 ! nucleotidyltransferase activity +created_by: mah +creation_date: 2009-04-15T11:06:07Z + +[Term] +id: GO:0070570 +name: regulation of neuron projection regeneration +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah] +is_a: GO:0010975 ! regulation of neuron projection development +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031102 ! neuron projection regeneration +relationship: regulates GO:0031102 ! neuron projection regeneration +created_by: mah +creation_date: 2009-04-15T01:23:48Z + +[Term] +id: GO:0070571 +name: negative regulation of neuron projection regeneration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah] +synonym: "growth cone collapse" RELATED [GOC:pr] +is_a: GO:0010977 ! negative regulation of neuron projection development +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0070570 ! regulation of neuron projection regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031102 ! neuron projection regeneration +relationship: negatively_regulates GO:0031102 ! neuron projection regeneration +created_by: mah +creation_date: 2009-04-15T01:43:19Z + +[Term] +id: GO:0070572 +name: positive regulation of neuron projection regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage." [GOC:mah] +is_a: GO:0010976 ! positive regulation of neuron projection development +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0070570 ! regulation of neuron projection regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031102 ! neuron projection regeneration +relationship: positively_regulates GO:0031102 ! neuron projection regeneration +created_by: mah +creation_date: 2009-04-15T01:45:27Z + +[Term] +id: GO:0070573 +name: metallodipeptidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE] +synonym: "metallo-exo-dipeptidase activity" EXACT [GOC:rb] +synonym: "metalloexodipeptidase activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-2022398 "ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)" +xref: Reactome:R-HSA-2022405 "ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)" +xref: Reactome:R-HSA-2065355 "Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)" +is_a: GO:0008235 ! metalloexopeptidase activity +is_a: GO:0016805 ! dipeptidase activity +created_by: mah +creation_date: 2009-04-15T03:11:29Z + +[Term] +id: GO:0070574 +name: cadmium ion transmembrane transport +namespace: biological_process +def: "A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "cadmium ion membrane transport" EXACT [] +synonym: "transmembrane cadmium transport" EXACT [GOC:mah] +is_a: GO:0015691 ! cadmium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2009-04-20T03:31:47Z + +[Term] +id: GO:0070575 +name: peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation +namespace: biological_process +def: "The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation." [GOC:mah] +synonym: "peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah] +synonym: "peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation" EXACT [GOC:mah] +is_a: GO:0007323 ! peptide pheromone maturation +is_a: GO:0046999 ! regulation of conjugation +relationship: regulates GO:0000762 ! pheromone-induced unidirectional conjugation +created_by: mah +creation_date: 2009-04-20T04:32:07Z + +[Term] +id: GO:0070576 +name: vitamin D 24-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of C-24 of any form of vitamin D." [GOC:BHF, GOC:mah, PMID:15546903] +synonym: "calciferol 24-hydroxylase activity" NARROW [GOC:rl] +synonym: "cholecalciferol 24-hydroxylase activity" NARROW [GOC:rl] +synonym: "ergocalciferol 24-hydroxylase activity" NARROW [GOC:rl] +synonym: "vitamin D2 24-hydroxylase activity" NARROW [GOC:rl] +synonym: "vitamin D3 24-hydroxylase activity" NARROW [GOC:rl] +is_a: GO:0004497 ! monooxygenase activity +created_by: mah +creation_date: 2009-04-21T02:20:52Z + +[Term] +id: GO:0070577 +name: lysine-acetylated histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation." [GOC:BHF, GOC:mah, GOC:rl, PMID:17582821] +synonym: "acetylated histone residue binding" BROAD [GOC:rl] +is_a: GO:0042393 ! histone binding +is_a: GO:0140033 ! acetylation-dependent protein binding +created_by: mah +creation_date: 2009-04-21T03:03:35Z + +[Term] +id: GO:0070578 +name: RISC-loading complex +namespace: cellular_component +def: "A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity." [GOC:ab, GOC:BHF, GOC:nc, GOC:rph, PMID:18178619, PMID:19820710] +synonym: "microRNA loading complex" EXACT [GOC:ab] +synonym: "miRLC" EXACT [GOC:ab] +synonym: "RLC" RELATED [GOC:ab, GOC:mah] +is_a: GO:1902555 ! endoribonuclease complex +created_by: mah +creation_date: 2009-04-22T01:40:19Z + +[Term] +id: GO:0070579 +name: methylcytosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2." [PMID:19372391] +xref: Reactome:R-HSA-5220952 "TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine" +xref: Reactome:R-HSA-5220990 "TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine" +xref: Reactome:R-HSA-5221014 "TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine" +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +created_by: mah +creation_date: 2009-04-22T02:29:41Z + +[Term] +id: GO:0070580 +name: base J metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J." [PMID:19114062] +synonym: "base J metabolism" EXACT [GOC:mah] +synonym: "beta-D-glucosyl-HOMedU metabolic process" EXACT [GOC:mah] +synonym: "beta-D-glucosyl-hydroxymethyluracil metabolism" EXACT [PMID:19114062] +is_a: GO:0006304 ! DNA modification +created_by: mah +creation_date: 2009-04-22T02:37:23Z + +[Term] +id: GO:0070581 +name: rolling circle DNA replication +namespace: biological_process +def: "A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon." [GOC:cb, GOC:mah, ISBN:0198506732] +synonym: "rolling circle replication" EXACT [GOC:cb] +is_a: GO:0006261 ! DNA-dependent DNA replication +created_by: mah +creation_date: 2009-04-22T02:53:52Z + +[Term] +id: GO:0070582 +name: theta DNA replication +namespace: biological_process +def: "A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template." [GOC:cb, GOC:mah, ISBN:0198506732] +synonym: "theta replication" EXACT [GOC:cb] +is_a: GO:0006261 ! DNA-dependent DNA replication +created_by: mah +creation_date: 2009-04-22T02:54:50Z + +[Term] +id: GO:0070583 +name: spore membrane bending pathway +namespace: biological_process +def: "The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore." [GOC:dgf, PMID:18756268] +synonym: "ascospore-type prospore membrane bending" EXACT [GOC:mah] +synonym: "forespore membrane bending" EXACT [GOC:mah] +synonym: "FSM bending" EXACT [GOC:mah] +is_a: GO:0061024 ! membrane organization +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0032120 ! ascospore-type prospore membrane formation +created_by: mah +creation_date: 2009-04-24T10:48:09Z + +[Term] +id: GO:0070584 +name: mitochondrion morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mitochondrion are generated and organized." [GOC:mah] +comment: Note that this term is intended for annotation of gene products involved in mitochondrial shape changes associated with development; an example is the morphogenesis of the Nebenkern during spermatogenesis. +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0032990 ! cell part morphogenesis +created_by: mah +creation_date: 2009-04-24T10:54:19Z + +[Term] +id: GO:0070585 +name: protein localization to mitochondrion +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the mitochondrion." [GOC:ecd] +synonym: "protein localisation in mitochondrion" EXACT [GOC:mah] +synonym: "protein localization in mitochondrion" EXACT [] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2009-04-24T02:31:18Z + +[Term] +id: GO:0070586 +name: cell-cell adhesion involved in gastrulation +namespace: biological_process +def: "The attachment of one cell to another cell affecting gastrulation." [GOC:dsf, PMID:19091770] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0007369 ! gastrulation +created_by: mah +creation_date: 2009-04-24T02:48:23Z + +[Term] +id: GO:0070587 +name: regulation of cell-cell adhesion involved in gastrulation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation." [GOC:dsf, PMID:19091770] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070586 ! cell-cell adhesion involved in gastrulation +relationship: regulates GO:0070586 ! cell-cell adhesion involved in gastrulation +created_by: mah +creation_date: 2009-04-24T02:51:07Z + +[Term] +id: GO:0070588 +name: calcium ion transmembrane transport +namespace: biological_process +def: "A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "calcium ion membrane transport" EXACT [] +synonym: "transmembrane calcium transport" EXACT [GOC:mah] +is_a: GO:0006816 ! calcium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2009-04-28T10:44:09Z + +[Term] +id: GO:0070589 +name: cellular component macromolecule biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component." [GOC:mah] +synonym: "cellular component macromolecule biosynthesis" EXACT [GOC:mah] +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +relationship: part_of GO:0044085 ! cellular component biogenesis +created_by: mah +creation_date: 2009-04-28T11:01:25Z + +[Term] +id: GO:0070590 +name: spore wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore." [GOC:mah] +is_a: GO:0042546 ! cell wall biogenesis +relationship: part_of GO:0030435 ! sporulation resulting in formation of a cellular spore +created_by: mah +creation_date: 2009-04-28T01:06:10Z + +[Term] +id: GO:0070591 +name: ascospore wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall." [GOC:mah] +is_a: GO:0009272 ! fungal-type cell wall biogenesis +is_a: GO:0070590 ! spore wall biogenesis +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0030437 ! ascospore formation +created_by: mah +creation_date: 2009-04-28T01:12:11Z + +[Term] +id: GO:0070592 +name: cell wall polysaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall." [GOC:mah] +synonym: "cell wall polysaccharide anabolism" EXACT [GOC:mah] +synonym: "cell wall polysaccharide biosynthesis" EXACT [GOC:mah] +synonym: "cell wall polysaccharide synthesis" EXACT [GOC:mah] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process +is_a: GO:0033692 ! cellular polysaccharide biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process +created_by: mah +creation_date: 2009-04-28T01:25:54Z + +[Term] +id: GO:0070593 +name: dendrite self-avoidance +namespace: biological_process +def: "The process in which dendrites recognize and avoid contact with sister dendrites from the same cell." [GOC:sart, PMID:17482551] +synonym: "dendrite repulsion" EXACT [GOC:sart] +is_a: GO:0008038 ! neuron recognition +created_by: mah +creation_date: 2009-04-28T03:29:14Z + +[Term] +id: GO:0070594 +name: juvenile hormone response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone." [GOC:sart, PMID:17956872] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "JHRE binding" EXACT [GOC:mah] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: mah +creation_date: 2009-04-28T03:31:27Z + +[Term] +id: GO:0070595 +name: (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +synonym: "1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0030978 ! alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-28T03:35:03Z + +[Term] +id: GO:0070596 +name: (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan anabolism" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan biosynthesis" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan biosynthetic process" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan formation" EXACT [GOC:mah] +synonym: "alpha-1,3 glucan synthesis" EXACT [GOC:mah] +is_a: GO:0030979 ! alpha-glucan biosynthetic process +is_a: GO:0070595 ! (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-28T03:39:24Z + +[Term] +id: GO:0070597 +name: cell wall (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process +is_a: GO:0070595 ! (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-28T04:03:00Z + +[Term] +id: GO:0070598 +name: cell wall (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "cell wall 1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3-glucan anabolism" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3-glucan biosynthesis" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3-glucan formation" EXACT [GOC:mah] +synonym: "cell wall alpha-1,3-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0070592 ! cell wall polysaccharide biosynthetic process +is_a: GO:0070596 ! (1->3)-alpha-glucan biosynthetic process +is_a: GO:0070597 ! cell wall (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-28T04:04:59Z + +[Term] +id: GO:0070599 +name: fungal-type cell wall (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "ascospore wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +synonym: "ascospore wall 1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "ascospore wall alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "ascospore wall alpha-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0070597 ! cell wall (1->3)-alpha-glucan metabolic process +is_a: GO:0071966 ! fungal-type cell wall polysaccharide metabolic process +created_by: mah +creation_date: 2009-04-28T04:07:23Z + +[Term] +id: GO:0070600 +name: fungal-type cell wall (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores." [GOC:mah] +synonym: "fungal-type cell wall 1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall alpha-1,3-glucan anabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall alpha-1,3-glucan biosynthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall alpha-1,3-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "fungal-type cell wall alpha-1,3-glucan formation" EXACT [GOC:mah] +synonym: "fungal-type cell wall alpha-1,3-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0051278 ! fungal-type cell wall polysaccharide biosynthetic process +is_a: GO:0070598 ! cell wall (1->3)-alpha-glucan biosynthetic process +is_a: GO:0070599 ! fungal-type cell wall (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-28T04:09:48Z + +[Term] +id: GO:0070601 +name: centromeric sister chromatid cohesion +namespace: biological_process +def: "The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome." [GOC:mah] +synonym: "sister chromatid cohesion at centromere" EXACT [GOC:mah] +is_a: GO:0007062 ! sister chromatid cohesion +created_by: mah +creation_date: 2009-04-28T04:31:00Z + +[Term] +id: GO:0070602 +name: regulation of centromeric sister chromatid cohesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome." [GOC:mah] +synonym: "regulation of sister chromatid cohesion at centromere" EXACT [GOC:mah] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070601 ! centromeric sister chromatid cohesion +relationship: regulates GO:0070601 ! centromeric sister chromatid cohesion +created_by: mah +creation_date: 2009-04-28T04:32:53Z + +[Term] +id: GO:0070603 +name: SWI/SNF superfamily-type complex +namespace: cellular_component +alt_id: GO:0090544 +def: "A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP." [GOC:bhm, GOC:krc, GOC:mah, PMID:16155938] +subset: gocheck_do_not_manually_annotate +synonym: "BAF-type complex" EXACT [] +synonym: "SWI-SNF global transcription activator complex" RELATED [CORUM:224] +synonym: "SWI-SNF-type complex" EXACT [GOC:mah] +synonym: "SWI/SNF-type complex" RELATED [GOC:krc] +synonym: "SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex" RELATED [GOC:krc] +is_a: GO:1904949 ! ATPase complex +relationship: part_of GO:0000790 ! nuclear chromatin +created_by: mah +creation_date: 2009-04-29T12:55:46Z + +[Term] +id: GO:0070605 +name: regulation of (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0032948 ! regulation of alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070595 ! (1->3)-alpha-glucan metabolic process +relationship: regulates GO:0070595 ! (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-29T01:20:12Z + +[Term] +id: GO:0070606 +name: regulation of (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "regulation of 1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan formation" EXACT [GOC:mah] +synonym: "regulation of alpha-1,3 glucan synthesis" EXACT [GOC:mah] +is_a: GO:0032949 ! regulation of alpha-glucan biosynthetic process +is_a: GO:0070605 ! regulation of (1->3)-alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070596 ! (1->3)-alpha-glucan biosynthetic process +relationship: regulates GO:0070596 ! (1->3)-alpha-glucan biosynthetic process +created_by: mah +creation_date: 2009-04-29T01:22:45Z + +[Term] +id: GO:0070607 +name: regulation of cell wall (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0070605 ! regulation of (1->3)-alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070597 ! cell wall (1->3)-alpha-glucan metabolic process +relationship: regulates GO:0070597 ! cell wall (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-29T01:24:57Z + +[Term] +id: GO:0070608 +name: regulation of cell wall (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells." [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "regulation of cell wall 1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3-glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3-glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3-glucan formation" EXACT [GOC:mah] +synonym: "regulation of cell wall alpha-1,3-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0070606 ! regulation of (1->3)-alpha-glucan biosynthetic process +is_a: GO:0070607 ! regulation of cell wall (1->3)-alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070598 ! cell wall (1->3)-alpha-glucan biosynthetic process +relationship: regulates GO:0070598 ! cell wall (1->3)-alpha-glucan biosynthetic process +created_by: mah +creation_date: 2009-04-29T01:27:15Z + +[Term] +id: GO:0070609 +name: regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores." [GOC:mah] +synonym: "regulation of ascospore wall 1,3-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "regulation of ascospore wall alpha-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "regulation of ascospore wall alpha-1,3 glucan metabolism" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] +is_a: GO:0070607 ! regulation of cell wall (1->3)-alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070599 ! fungal-type cell wall (1->3)-alpha-glucan metabolic process +relationship: regulates GO:0070599 ! fungal-type cell wall (1->3)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-04-29T01:29:02Z + +[Term] +id: GO:0070610 +name: regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores." [GOC:mah] +synonym: "regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:dph, GOC:tb] +synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan formation" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall alpha-1,3-glucan anabolism" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall alpha-1,3-glucan formation" EXACT [GOC:mah] +synonym: "regulation of fungal-type cell wall alpha-1,3-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0032995 ! regulation of fungal-type cell wall biogenesis +is_a: GO:0070608 ! regulation of cell wall (1->3)-alpha-glucan biosynthetic process +is_a: GO:0070609 ! regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070600 ! fungal-type cell wall (1->3)-alpha-glucan biosynthetic process +relationship: regulates GO:0070600 ! fungal-type cell wall (1->3)-alpha-glucan biosynthetic process +created_by: mah +creation_date: 2009-04-29T01:32:19Z + +[Term] +id: GO:0070611 +name: histone methyltransferase activity (H3-R2 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3." [GOC:mah, PMID:17898714] +synonym: "histone methylase activity (H3-R2 specific)" EXACT [GOC:mah] +synonym: "histone-arginine N-methyltransferase activity (H3-R2 specific)" EXACT [GOC:mah] +is_a: GO:0008469 ! histone-arginine N-methyltransferase activity +relationship: part_of GO:0034970 ! histone H3-R2 methylation +created_by: mah +creation_date: 2009-04-29T02:04:44Z + +[Term] +id: GO:0070612 +name: histone methyltransferase activity (H2A-R3 specific) +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A." [GOC:mah, PMID:17898714] +synonym: "histone methylase activity (H2A-R3 specific)" EXACT [GOC:mah] +synonym: "histone-arginine N-methyltransferase activity (H2A-R3 specific)" EXACT [GOC:mah] +is_a: GO:0008469 ! histone-arginine N-methyltransferase activity +created_by: mah +creation_date: 2009-04-29T02:06:45Z + +[Term] +id: GO:0070613 +name: regulation of protein processing +namespace: biological_process +alt_id: GO:0010953 +def: "Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein." [GOC:mah] +synonym: "regulation of protein maturation by peptide bond cleavage" EXACT [] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:1903317 ! regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016485 ! protein processing +relationship: regulates GO:0016485 ! protein processing +created_by: mah +creation_date: 2009-04-29T02:49:14Z + +[Term] +id: GO:0070614 +name: tungstate ion transport +namespace: biological_process +def: "The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten." [GOC:dh] +is_a: GO:0015698 ! inorganic anion transport +created_by: mah +creation_date: 2009-04-29T03:07:40Z + +[Term] +id: GO:0070615 +name: nucleosome-dependent ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes." [GOC:mah, PMID:19165147] +synonym: "nucleosome-activated ATPase activity" EXACT [GOC:mah] +is_a: GO:0016887 ! ATPase activity +created_by: mah +creation_date: 2009-04-29T03:15:31Z + +[Term] +id: GO:0070616 +name: regulation of thiamine diphosphate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate." [GOC:mah] +synonym: "regulation of thiamin diphosphate biosynthetic process" EXACT [] +synonym: "regulation of thiamine diphosphate anabolism" EXACT [GOC:mah] +synonym: "regulation of thiamine diphosphate biosynthesis" EXACT [GOC:mah] +synonym: "regulation of thiamine diphosphate formation" EXACT [GOC:mah] +synonym: "regulation of thiamine diphosphate synthesis" EXACT [GOC:mah] +is_a: GO:0019220 ! regulation of phosphate metabolic process +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009229 ! thiamine diphosphate biosynthetic process +relationship: regulates GO:0009229 ! thiamine diphosphate biosynthetic process +created_by: mah +creation_date: 2009-04-29T03:37:35Z + +[Term] +id: GO:0070617 +name: negative regulation of thiamine diphosphate biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate." [GOC:mah] +synonym: "down regulation of thiamine diphosphate biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of thiamine diphosphate biosynthetic process" EXACT [GOC:mah] +synonym: "downregulation of thiamine diphosphate biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of thiamine diphosphate biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of thiamin diphosphate biosynthetic process" EXACT [] +synonym: "negative regulation of thiamine diphosphate anabolism" EXACT [GOC:mah] +synonym: "negative regulation of thiamine diphosphate biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of thiamine diphosphate formation" EXACT [GOC:mah] +synonym: "negative regulation of thiamine diphosphate synthesis" EXACT [GOC:mah] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0070616 ! regulation of thiamine diphosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009229 ! thiamine diphosphate biosynthetic process +relationship: negatively_regulates GO:0009229 ! thiamine diphosphate biosynthetic process +created_by: mah +creation_date: 2009-04-29T03:39:48Z + +[Term] +id: GO:0070618 +name: Grb2-Sos complex +namespace: cellular_component +def: "A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267, PMID:8940013] +synonym: "Grb2-mSos1 complex" NARROW [CORUM:2545] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-04-29T04:19:02Z + +[Term] +id: GO:0070619 +name: Shc-Grb2-Sos complex +namespace: cellular_component +def: "A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7970708, PMID:8940013] +synonym: "Shc-Grb2-mSos1 complex, EGF stimulated" NARROW [CORUM:2553] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-04-29T04:30:00Z + +[Term] +id: GO:0070620 +name: EGFR-Grb2-Sos complex +namespace: cellular_component +def: "A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267, PMID:8940013] +synonym: "Egfr-Grb2-mSos1 complex, EGF stimulated" NARROW [CORUM:2548] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-04-29T04:36:30Z + +[Term] +id: GO:0070621 +name: EGFR-Shc-Grb2-Sos complex +namespace: cellular_component +def: "A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267, PMID:8940013] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-04-29T04:38:10Z + +[Term] +id: GO:0070622 +name: UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex +namespace: cellular_component +def: "A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits." [GOC:mah, PMID:8940155] +synonym: "N-acetylglucosamine-1-phosphotransferase complex" RELATED [CORUM:406] +synonym: "UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex" EXACT [PMID:8940155] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +relationship: part_of GO:0005764 ! lysosome +created_by: mah +creation_date: 2009-04-29T04:50:35Z + +[Term] +id: GO:0070623 +name: regulation of thiamine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine." [GOC:mah] +synonym: "regulation of thiamin biosynthetic process" EXACT [] +synonym: "regulation of thiamine anabolism" EXACT [GOC:mah] +synonym: "regulation of thiamine biosynthesis" EXACT [GOC:mah] +synonym: "regulation of thiamine formation" EXACT [GOC:mah] +synonym: "regulation of thiamine synthesis" EXACT [GOC:mah] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009228 ! thiamine biosynthetic process +relationship: regulates GO:0009228 ! thiamine biosynthetic process +created_by: mah +creation_date: 2009-05-01T03:15:49Z + +[Term] +id: GO:0070624 +name: negative regulation of thiamine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine." [GOC:mah] +synonym: "down regulation of thiamine biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of thiamine biosynthetic process" EXACT [GOC:mah] +synonym: "downregulation of thiamine biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of thiamine biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of thiamin biosynthetic process" EXACT [] +synonym: "negative regulation of thiamine anabolism" EXACT [GOC:mah] +synonym: "negative regulation of thiamine biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of thiamine formation" EXACT [GOC:mah] +synonym: "negative regulation of thiamine synthesis" EXACT [GOC:mah] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0070623 ! regulation of thiamine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009228 ! thiamine biosynthetic process +relationship: negatively_regulates GO:0009228 ! thiamine biosynthetic process +created_by: mah +creation_date: 2009-05-01T03:20:41Z + +[Term] +id: GO:0070625 +name: zymogen granule exocytosis +namespace: biological_process +def: "The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions." [GOC:BHF, GOC:vk, PMID:17442889] +is_a: GO:0017156 ! calcium-ion regulated exocytosis +created_by: mah +creation_date: 2009-05-01T03:56:02Z + +[Term] +id: GO:0070626 +name: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide." [GOC:mah, GOC:pde] +synonym: "adenylosuccinase activity" BROAD [EC:4.3.2.2, GOC:mah] +synonym: "adenylosuccinate lyase activity" BROAD [GOC:mah] +synonym: "succino AMP-lyase activity" BROAD [EC:4.3.2.2, GOC:mah] +xref: EC:4.3.2.2 +xref: KEGG_REACTION:R04559 +xref: MetaCyc:AICARSYN-RXN +is_a: GO:0016842 ! amidine-lyase activity +created_by: mah +creation_date: 2009-05-01T04:13:49Z + +[Term] +id: GO:0070628 +name: proteasome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation." [GOC:mah] +subset: goslim_chembl +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2009-05-01T04:38:58Z + +[Term] +id: GO:0070629 +name: (1->4)-alpha-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "(1->4)-alpha-D-glucan metabolism" EXACT [GOC:mah] +synonym: "1,4-alpha-D-glucan metabolism" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan metabolism" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan metabolic process" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0030978 ! alpha-glucan metabolic process +created_by: mah +creation_date: 2009-05-01T04:45:42Z + +[Term] +id: GO:0070630 +name: (1->4)-alpha-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds." [GOC:mah] +synonym: "(1->4)-alpha-D-glucan anabolism" EXACT [GOC:mah] +synonym: "(1->4)-alpha-D-glucan biosynthesis" EXACT [GOC:mah] +synonym: "(1->4)-alpha-D-glucan formation" EXACT [GOC:mah] +synonym: "(1->4)-alpha-D-glucan synthesis" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan anabolism" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan biosynthesis" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan formation" EXACT [GOC:mah] +synonym: "1,4-alpha-glucan synthesis" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan anabolism" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan biosynthesis" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan biosynthetic process" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan formation" EXACT [GOC:mah] +synonym: "alpha-1,4 glucan synthesis" EXACT [GOC:mah] +is_a: GO:0030979 ! alpha-glucan biosynthetic process +is_a: GO:0070629 ! (1->4)-alpha-glucan metabolic process +created_by: mah +creation_date: 2009-05-01T04:46:34Z + +[Term] +id: GO:0070631 +name: spindle pole body localization +namespace: biological_process +alt_id: GO:0071790 +alt_id: GO:1990944 +def: "Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells." [GOC:mah] +synonym: "establishment and maintenance of spindle pole body localization" EXACT [GOC:mah] +synonym: "establishment of spindle pole body localisation in nuclear envelope" NARROW [GOC:mah] +synonym: "establishment of spindle pole body localization in nuclear envelope" NARROW [] +synonym: "establishment of spindle pole body localization to nuclear envelope" NARROW [] +synonym: "maintenance of spindle pole body localization" NARROW [] +synonym: "spindle pole body localisation" EXACT [GOC:mah] +is_a: GO:0051641 ! cellular localization +is_a: GO:0061842 ! microtubule organizing center localization +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19149 xsd:anyURI +created_by: mah +creation_date: 2009-05-06T02:21:38Z + +[Term] +id: GO:0070633 +name: transepithelial transport +namespace: biological_process +def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363] +is_a: GO:0006810 ! transport +created_by: mah +creation_date: 2009-05-06T03:31:02Z + +[Term] +id: GO:0070634 +name: transepithelial ammonium transport +namespace: biological_process +def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] +is_a: GO:0015696 ! ammonium transport +is_a: GO:0070633 ! transepithelial transport +created_by: mah +creation_date: 2009-05-06T03:34:43Z + +[Term] +id: GO:0070635 +name: nicotinamide riboside hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose." [MetaCyc:RXN-8441, PMID:19001417] +synonym: "N-ribosylnicotinamide hydrolase activity" EXACT [CHEBI:15927] +synonym: "nicotinamide ribonucleoside hydrolase activity" EXACT [CHEBI:15927] +xref: MetaCyc:RXN-8441 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: mah +creation_date: 2009-05-07T02:01:42Z + +[Term] +id: GO:0070636 +name: nicotinic acid riboside hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose." [GOC:mah, PMID:19001417] +synonym: "D-ribosylnicotinate hydrolase activity" EXACT [GOC:mah] +synonym: "D-ribosylnicotinic acid hydrolase activity" EXACT [CHEBI:27748] +synonym: "nicotinate ribonucleoside hydrolase activity" EXACT [GOC:mah] +synonym: "nicotinate riboside hydrolase activity" EXACT [GOC:mah] +synonym: "nicotinic acid ribonucleoside hydrolase activity" EXACT [GOC:mah] +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: mah +creation_date: 2009-05-07T02:12:00Z + +[Term] +id: GO:0070637 +name: pyridine nucleoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose." [GOC:mah] +synonym: "pyridine nucleoside metabolism" EXACT [GOC:mah] +is_a: GO:0009116 ! nucleoside metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +created_by: mah +creation_date: 2009-05-07T02:24:21Z + +[Term] +id: GO:0070638 +name: pyridine nucleoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose." [GOC:mah] +synonym: "pyridine nucleoside breakdown" EXACT [GOC:mah] +synonym: "pyridine nucleoside catabolism" EXACT [GOC:mah] +synonym: "pyridine nucleoside degradation" EXACT [GOC:mah] +is_a: GO:0009164 ! nucleoside catabolic process +is_a: GO:0070637 ! pyridine nucleoside metabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process +created_by: mah +creation_date: 2009-05-07T02:27:14Z + +[Term] +id: GO:0070639 +name: vitamin D2 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol." [GOC:BHF, GOC:mah] +synonym: "calciferol metabolic process" EXACT [CHEBI:28934] +synonym: "ergocalciferol metabolic process" EXACT [CHEBI:28934] +synonym: "vitamin D2 metabolism" EXACT [GOC:mah] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042359 ! vitamin D metabolic process +created_by: mah +creation_date: 2009-05-08T02:11:35Z + +[Term] +id: GO:0070640 +name: vitamin D3 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol." [GOC:BHF, GOC:mah] +synonym: "calciol metabolic process" EXACT [CHEBI:28940] +synonym: "cholecalciferol metabolic process" EXACT [CHEBI:28940] +synonym: "vitamin D3 metabolism" EXACT [GOC:mah] +is_a: GO:0042359 ! vitamin D metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: mah +creation_date: 2009-05-08T02:24:24Z + +[Term] +id: GO:0070641 +name: vitamin D4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol." [GOC:BHF, GOC:mah] +synonym: "vitamin D4 metabolism" EXACT [GOC:mah] +is_a: GO:0042359 ! vitamin D metabolic process +created_by: mah +creation_date: 2009-05-08T02:33:01Z + +[Term] +id: GO:0070642 +name: vitamin D5 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol." [GOC:BHF, GOC:mah, PubChem_Compound:9547700] +synonym: "vitamin D5 metabolism" EXACT [GOC:mah] +is_a: GO:0042359 ! vitamin D metabolic process +created_by: mah +creation_date: 2009-05-08T02:47:41Z + +[Term] +id: GO:0070643 +name: vitamin D 25-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the hydroxylation of C-25 of any form of vitamin D." [GOC:BHF, GOC:mah] +synonym: "calciferol 25-hydroxylase activity" NARROW [GOC:mah] +synonym: "cholecalciferol 25-hydroxylase activity" NARROW [GOC:mah] +synonym: "ergocalciferol 25-hydroxylase activity" NARROW [GOC:mah] +synonym: "vitamin D2 25-hydroxylase activity" NARROW [GOC:mah] +is_a: GO:0004497 ! monooxygenase activity +created_by: mah +creation_date: 2009-05-08T03:42:29Z + +[Term] +id: GO:0070644 +name: vitamin D response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum." [GOC:BHF, GOC:vk, PMID:17426122] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "VDRE binding" EXACT [GOC:vk, PMID:17426122] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: mah +creation_date: 2009-05-08T04:23:44Z + +[Term] +id: GO:0070645 +name: Ubisch body +namespace: cellular_component +def: "A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development." [GOC:ecd, GOC:mah, PMID:14612572, PMID:16524248] +synonym: "orbicule" EXACT [PMID:14612572] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031012 ! extracellular matrix +created_by: mah +creation_date: 2009-05-11T11:35:33Z + +[Term] +id: GO:0070646 +name: protein modification by small protein removal +namespace: biological_process +def: "A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein." [GOC:mah] +is_a: GO:0006508 ! proteolysis +is_a: GO:0070647 ! protein modification by small protein conjugation or removal +created_by: mah +creation_date: 2009-05-11T01:58:15Z + +[Term] +id: GO:0070647 +name: protein modification by small protein conjugation or removal +namespace: biological_process +def: "A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein." [GOC:mah] +subset: goslim_drosophila +subset: goslim_pombe +subset: goslim_yeast +is_a: GO:0006464 ! cellular protein modification process +created_by: mah +creation_date: 2009-05-11T02:54:03Z + +[Term] +id: GO:0070648 +name: formin-nucleated actin cable +namespace: cellular_component +def: "An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth." [PMID:14671023, PMID:16959963] +is_a: GO:0097518 ! parallel actin filament bundle +created_by: mah +creation_date: 2009-05-12T02:09:57Z + +[Term] +id: GO:0070649 +name: formin-nucleated actin cable assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins." [GOC:mah, PMID:14671023, PMID:16959963] +synonym: "formin-nucleated actin cable formation" EXACT [GOC:mah] +is_a: GO:0030046 ! parallel actin filament bundle assembly +is_a: GO:0110009 ! formin-nucleated actin cable organization +created_by: mah +creation_date: 2009-05-12T02:14:36Z + +[Term] +id: GO:0070650 +name: actin filament bundle distribution +namespace: biological_process +def: "Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell." [GOC:mah] +is_a: GO:0061572 ! actin filament bundle organization +created_by: mah +creation_date: 2009-05-12T02:20:58Z + +[Term] +id: GO:0070651 +name: nonfunctional rRNA decay +namespace: biological_process +def: "An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system." [GOC:mah, GOC:rn, PMID:17188037, PMID:19390089] +synonym: "NRD" RELATED [GOC:rn] +is_a: GO:0016075 ! rRNA catabolic process +created_by: mah +creation_date: 2009-05-28T02:22:49Z + +[Term] +id: GO:0070652 +name: HAUS complex +namespace: cellular_component +def: "A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex." [PMID:19427217] +synonym: "HAUS augmin complex" EXACT [GOC:mm2] +is_a: GO:0005875 ! microtubule associated complex +created_by: mah +creation_date: 2009-05-28T03:21:01Z + +[Term] +id: GO:0070653 +name: high-density lipoprotein particle receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a high-density lipoprotein receptor." [GOC:BHF, GOC:mah] +synonym: "HDL receptor binding" EXACT [GOC:mah] +synonym: "high-density lipoprotein receptor binding" EXACT [GOC:dph] +is_a: GO:0070325 ! lipoprotein particle receptor binding +created_by: mah +creation_date: 2009-05-28T03:44:33Z + +[Term] +id: GO:0070654 +name: sensory epithelium regeneration +namespace: biological_process +def: "The regrowth of a sensory epithelium following its loss or destruction." [GOC:dsf, PMID:19381250] +is_a: GO:1990399 ! epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:02:27Z + +[Term] +id: GO:0070655 +name: mechanosensory epithelium regeneration +namespace: biological_process +def: "The regrowth of lost or destroyed mechanosensory epithelia." [GOC:dsf, PMID:19381250] +is_a: GO:0070654 ! sensory epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:05:18Z + +[Term] +id: GO:0070656 +name: mechanoreceptor differentiation involved in mechanosensory epithelium regeneration +namespace: biological_process +def: "Differentiation of new mechanoreceptors to replace those lost or destroyed by injury." [GOC:dsf, PMID:19381250] +is_a: GO:0042490 ! mechanoreceptor differentiation +intersection_of: GO:0042490 ! mechanoreceptor differentiation +intersection_of: part_of GO:0070655 ! mechanosensory epithelium regeneration +relationship: part_of GO:0070655 ! mechanosensory epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:08:13Z + +[Term] +id: GO:0070657 +name: neuromast regeneration +namespace: biological_process +def: "The regrowth of a neuromast following its loss or destruction." [GOC:dsf, PMID:19381250] +is_a: GO:0070655 ! mechanosensory epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:11:44Z + +[Term] +id: GO:0070658 +name: neuromast hair cell differentiation involved in neuromast regeneration +namespace: biological_process +def: "Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury." [GOC:dsf, PMID:19381250] +is_a: GO:0048886 ! neuromast hair cell differentiation +is_a: GO:0070656 ! mechanoreceptor differentiation involved in mechanosensory epithelium regeneration +intersection_of: GO:0048886 ! neuromast hair cell differentiation +intersection_of: part_of GO:0070657 ! neuromast regeneration +relationship: part_of GO:0070657 ! neuromast regeneration +created_by: mah +creation_date: 2009-05-28T04:16:27Z + +[Term] +id: GO:0070659 +name: inner ear sensory epithelium regeneration +namespace: biological_process +def: "The regrowth of lost or destroyed inner ear sensory epithelia." [GOC:dsf, PMID:19381250] +is_a: GO:0070655 ! mechanosensory epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:21:09Z + +[Term] +id: GO:0070660 +name: inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration +namespace: biological_process +def: "Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury." [GOC:dsf, PMID:19381250] +is_a: GO:0060113 ! inner ear receptor cell differentiation +is_a: GO:0070656 ! mechanoreceptor differentiation involved in mechanosensory epithelium regeneration +intersection_of: GO:0060113 ! inner ear receptor cell differentiation +intersection_of: part_of GO:0070659 ! inner ear sensory epithelium regeneration +relationship: part_of GO:0070659 ! inner ear sensory epithelium regeneration +created_by: mah +creation_date: 2009-05-28T04:24:23Z + +[Term] +id: GO:0070661 +name: leukocyte proliferation +namespace: biological_process +def: "The expansion of a leukocyte population by cell division." [GOC:add] +is_a: GO:0008283 ! cell population proliferation +created_by: mah +creation_date: 2009-05-28T05:25:28Z + +[Term] +id: GO:0070662 +name: mast cell proliferation +namespace: biological_process +def: "The expansion of a mast cell population by cell division." [GOC:add] +is_a: GO:0070661 ! leukocyte proliferation +created_by: mah +creation_date: 2009-05-28T05:27:51Z + +[Term] +id: GO:0070663 +name: regulation of leukocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070661 ! leukocyte proliferation +relationship: regulates GO:0070661 ! leukocyte proliferation +created_by: mah +creation_date: 2009-05-28T05:30:39Z + +[Term] +id: GO:0070664 +name: negative regulation of leukocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] +synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah] +synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah] +synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah] +synonym: "inhibition of leukocyte proliferation" NARROW [GOC:mah] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070661 ! leukocyte proliferation +relationship: negatively_regulates GO:0070661 ! leukocyte proliferation +created_by: mah +creation_date: 2009-05-28T05:34:50Z + +[Term] +id: GO:0070665 +name: positive regulation of leukocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] +synonym: "activation of leukocyte proliferation" NARROW [GOC:mah] +synonym: "stimulation of leukocyte proliferation" NARROW [GOC:mah] +synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah] +synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah] +synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070661 ! leukocyte proliferation +relationship: positively_regulates GO:0070661 ! leukocyte proliferation +created_by: mah +creation_date: 2009-05-28T05:36:46Z + +[Term] +id: GO:0070666 +name: regulation of mast cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mast cell proliferation." [GOC:add, GOC:mah] +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070662 ! mast cell proliferation +relationship: regulates GO:0070662 ! mast cell proliferation +created_by: mah +creation_date: 2009-05-28T05:40:43Z + +[Term] +id: GO:0070667 +name: negative regulation of mast cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of mast cell proliferation." [GOC:add, GOC:mah] +synonym: "down regulation of mast cell proliferation" EXACT [GOC:mah] +synonym: "down-regulation of mast cell proliferation" EXACT [GOC:mah] +synonym: "downregulation of mast cell proliferation" EXACT [GOC:mah] +synonym: "inhibition of mast cell proliferation" NARROW [GOC:mah] +is_a: GO:0070664 ! negative regulation of leukocyte proliferation +is_a: GO:0070666 ! regulation of mast cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070662 ! mast cell proliferation +relationship: negatively_regulates GO:0070662 ! mast cell proliferation +created_by: mah +creation_date: 2009-05-28T05:45:11Z + +[Term] +id: GO:0070668 +name: positive regulation of mast cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of mast cell proliferation." [GOC:add, GOC:mah] +synonym: "activation of mast cell proliferation" NARROW [GOC:mah] +synonym: "stimulation of mast cell proliferation" NARROW [GOC:mah] +synonym: "up regulation of mast cell proliferation" EXACT [GOC:mah] +synonym: "up-regulation of mast cell proliferation" EXACT [GOC:mah] +synonym: "upregulation of mast cell proliferation" EXACT [GOC:mah] +is_a: GO:0070665 ! positive regulation of leukocyte proliferation +is_a: GO:0070666 ! regulation of mast cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070662 ! mast cell proliferation +relationship: positively_regulates GO:0070662 ! mast cell proliferation +created_by: mah +creation_date: 2009-05-28T05:48:30Z + +[Term] +id: GO:0070669 +name: response to interleukin-2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus." [GOC:mah] +synonym: "response to IL-2" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-05-29T09:59:43Z + +[Term] +id: GO:0070670 +name: response to interleukin-4 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus." [GOC:mah] +synonym: "response to IL-4" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-05-29T10:01:46Z + +[Term] +id: GO:0070671 +name: response to interleukin-12 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus." [GOC:mah] +synonym: "response to IL-12" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-05-29T10:02:31Z + +[Term] +id: GO:0070672 +name: response to interleukin-15 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus." [GOC:mah] +synonym: "response to IL-15" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-05-29T10:03:09Z + +[Term] +id: GO:0070673 +name: response to interleukin-18 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus." [GOC:mah] +synonym: "response to IL-18" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-05-29T10:03:52Z + +[Term] +id: GO:0070674 +name: hypoxanthine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+." [GOC:mah, GOC:pde] +synonym: "hypoxanthine oxidoreductase activity" BROAD [EC:1.17.1.4] +synonym: "hypoxanthine-NAD oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "hypoxanthine/NAD(+) oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "hypoxanthine/NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "hypoxanthine:NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] +synonym: "NAD-hypoxanthine dehydrogenase activity" EXACT [EC:1.17.1.4] +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor +created_by: mah +creation_date: 2009-05-29T01:02:13Z + +[Term] +id: GO:0070675 +name: hypoxanthine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2." [GOC:mah, GOC:pde] +synonym: "hypoxanthine-xanthine oxidase activity" BROAD [EC:1.17.3.2] +synonym: "hypoxanthine:O(2) oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "hypoxanthine:O2 oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "hypoxanthine:oxygen oxidoreductase activity" EXACT [EC:1.17.3.2] +synonym: "schardinger enzyme" RELATED [EC:1.17.3.2] +synonym: "Schardinger enzyme activity" RELATED [EC:1.17.3.2] +synonym: "xanthine oxidoreductase activity" BROAD [EC:1.17.3.2] +is_a: GO:0016727 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor +created_by: mah +creation_date: 2009-05-29T01:12:55Z + +[Term] +id: GO:0070676 +name: intralumenal vesicle formation +namespace: biological_process +def: "The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome." [GOC:jp, PMID:19234443] +synonym: "endosome membrane budding" EXACT [GOC:jp, GOC:mah] +is_a: GO:0006900 ! vesicle budding from membrane +is_a: GO:0007032 ! endosome organization +relationship: occurs_in GO:0010008 ! endosome membrane +created_by: mah +creation_date: 2009-05-29T02:02:30Z + +[Term] +id: GO:0070677 +name: rRNA (cytosine-2'-O-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine." [GOC:mah, PMID:19400805] +is_a: GO:0016434 ! rRNA (cytosine) methyltransferase activity +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity +created_by: mah +creation_date: 2009-05-29T03:37:53Z + +[Term] +id: GO:0070678 +name: preprotein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing." [GOC:imk, GOC:mah, PMID:12914940] +synonym: "unprocessed protein binding" EXACT [GOC:imk] +is_a: GO:0005515 ! protein binding +created_by: mah +creation_date: 2009-05-29T03:41:54Z + +[Term] +id: GO:0070679 +name: inositol 1,4,5 trisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate." [GOC:BHF, GOC:mah] +synonym: "InsP3 binding" EXACT [GOC:mah] +synonym: "IP3 binding" EXACT [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0043178 ! alcohol binding +created_by: mah +creation_date: 2009-05-29T04:07:00Z + +[Term] +id: GO:0070680 +name: asparaginyl-tRNAAsn biosynthesis via transamidation +namespace: biological_process +def: "A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase." [GOC:mah, MetaCyc:PWY490-4] +xref: MetaCyc:PWY490-4 +is_a: GO:0043039 ! tRNA aminoacylation +created_by: mah +creation_date: 2009-06-02T03:11:19Z + +[Term] +id: GO:0070681 +name: glutaminyl-tRNAGln biosynthesis via transamidation +namespace: biological_process +def: "A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase." [GOC:mah, MetaCyc:PWY-5921] +xref: MetaCyc:PWY-5921 +is_a: GO:0043039 ! tRNA aminoacylation +created_by: mah +creation_date: 2009-06-02T03:15:57Z + +[Term] +id: GO:0070682 +name: proteasome regulatory particle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex." [GOC:mah, GOC:rb, PMID:19412159] +synonym: "proteasome regulatory complex assembly" EXACT [GOC:mah] +is_a: GO:0043248 ! proteasome assembly +created_by: mah +creation_date: 2009-06-02T03:46:29Z + +[Term] +id: GO:0070684 +name: seminal clot liquefaction +namespace: biological_process +def: "The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa." [GOC:mah, PMID:18482984] +synonym: "semen liquefaction" EXACT [PMID:18482984] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0007320 ! insemination +created_by: mah +creation_date: 2009-06-02T04:33:54Z + +[Term] +id: GO:0070685 +name: macropinocytic cup +namespace: cellular_component +def: "A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin." [PMID:12538772, PMID:16968738, PMID:9044041] +synonym: "crown" EXACT [GOC:pf, PMID:9044041] +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: mah +creation_date: 2009-06-03T10:18:00Z + +[Term] +id: GO:0070686 +name: macropinocytic cup membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a macropinocytic cup." [GOC:mah] +synonym: "crown membrane" EXACT [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0070685 ! macropinocytic cup +created_by: mah +creation_date: 2009-06-03T10:52:25Z + +[Term] +id: GO:0070687 +name: macropinocytic cup cytoskeleton +namespace: cellular_component +def: "The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup." [GOC:mah] +synonym: "crown cytoskeleton" EXACT [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030864 ! cortical actin cytoskeleton +relationship: part_of GO:0070685 ! macropinocytic cup +created_by: mah +creation_date: 2009-06-03T10:59:50Z + +[Term] +id: GO:0070688 +name: obsolete MLL5-L complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively." [GOC:mah, PMID:19377461] +comment: This term was made obsolete because there is no evidence for the existence of this complex. +is_obsolete: true +created_by: mah +creation_date: 2009-06-03T11:50:18Z + +[Term] +id: GO:0070689 +name: L-threonine catabolic process to propionate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate." [GOC:bf, GOC:mah, MetaCyc:PWY-5437] +synonym: "L-threonine breakdown to propionate" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine catabolism to propionate" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine degradation to propionate" EXACT [GOC:bf, GOC:mah] +synonym: "threonine catabolic process to propionate" BROAD [GOC:bf] +xref: MetaCyc:PWY-5437 +is_a: GO:0006567 ! threonine catabolic process +is_a: GO:0019541 ! propionate metabolic process +is_a: GO:0042737 ! drug catabolic process +created_by: mah +creation_date: 2009-06-03T01:36:54Z + +[Term] +id: GO:0070690 +name: L-threonine catabolic process to acetyl-CoA +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA." [GOC:bf, GOC:mah, MetaCyc:PWY-5436] +synonym: "L-threonine breakdown to acetyl-CoA" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine catabolism to acetyl-CoA" EXACT [GOC:bf, GOC:mah] +synonym: "L-threonine degradation to acetyl-CoA" EXACT [GOC:bf, GOC:mah] +synonym: "threonine catabolic process to acetyl-CoA" BROAD [GOC:bf] +xref: MetaCyc:PWY-5436 +is_a: GO:0006084 ! acetyl-CoA metabolic process +is_a: GO:0006567 ! threonine catabolic process +is_a: GO:0042737 ! drug catabolic process +created_by: mah +creation_date: 2009-06-03T01:40:22Z + +[Term] +id: GO:0070691 +name: P-TEFb complex +namespace: cellular_component +def: "A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T." [GOC:mah, GOC:vw, PMID:16721054, PMID:19328067, Wikipedia:P-TEFb] +synonym: "Bur1/Bur2 complex" NARROW [PMID:16721054, PMID:19328067] +synonym: "cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex" NARROW [GOC:vw] +synonym: "cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex" NARROW [GOC:bhm] +synonym: "dimeric positive transcription elongation factor complex b" RELATED [] +synonym: "Sgv1/Bur2 complex" NARROW [GOC:mah] +is_a: GO:0008024 ! cyclin/CDK positive transcription elongation factor complex +created_by: mah +creation_date: 2009-06-03T03:12:56Z + +[Term] +id: GO:0070692 +name: CTDK-1 complex +namespace: cellular_component +def: "A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638)." [GOC:mah, GOC:vw, PMID:16721054, PMID:19328067] +synonym: "C-terminal domain kinase I complex" EXACT [PMID:15047695, PMID:16721054, PMID:19328067] +synonym: "CTDK-I complex" EXACT [PMID:15047695, PMID:16721054, PMID:19328067] +synonym: "Ctk complex" EXACT [PMID:16721054] +synonym: "trimeric positive transcription elongation factor complex b" RELATED [] +is_a: GO:0008024 ! cyclin/CDK positive transcription elongation factor complex +created_by: mah +creation_date: 2009-06-03T03:18:04Z + +[Term] +id: GO:0070693 +name: P-TEFb-cap methyltransferase complex +namespace: cellular_component +def: "A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase." [PMID:17332744, PMID:19328067] +synonym: "Cdk9-Pcm1 complex" NARROW [GOC:vw] +synonym: "P-TEFb-Pcm1 complex" NARROW [GOC:vw] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2009-06-04T02:38:58Z + +[Term] +id: GO:0070694 +name: deoxyribonucleoside 5'-monophosphate N-glycosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base." [GOC:ab, PMID:17234634] +synonym: "deoxynucleoside 5'-monophosphate N-glycosidase activity" EXACT [] +xref: EC:3.2.2 +xref: Reactome:R-HSA-8953339 "DNPH1 hydrolyses dGMP" +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: mah +creation_date: 2009-06-04T03:06:57Z + +[Term] +id: GO:0070695 +name: FHF complex +namespace: cellular_component +def: "A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex)." [GOC:ab, GOC:mah, PMID:18799622] +comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-06-04T03:17:29Z + +[Term] +id: GO:0070696 +name: transmembrane receptor protein serine/threonine kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity." [GOC:BHF, GOC:mah] +is_a: GO:0033612 ! receptor serine/threonine kinase binding +created_by: mah +creation_date: 2009-06-04T03:57:42Z + +[Term] +id: GO:0070697 +name: activin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an activin receptor." [GOC:BHF, GOC:vk] +is_a: GO:0070696 ! transmembrane receptor protein serine/threonine kinase binding +created_by: mah +creation_date: 2009-06-04T04:02:13Z + +[Term] +id: GO:0070698 +name: type I activin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type I activin receptor." [GOC:BHF, GOC:vk] +is_a: GO:0070697 ! activin receptor binding +created_by: mah +creation_date: 2009-06-04T04:15:21Z + +[Term] +id: GO:0070699 +name: type II activin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type II activin receptor." [GOC:BHF, GOC:vk] +is_a: GO:0070697 ! activin receptor binding +created_by: mah +creation_date: 2009-06-04T04:16:26Z + +[Term] +id: GO:0070700 +name: BMP receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a BMP receptor." [GOC:BHF, GOC:vk] +synonym: "bone morphogenetic protein receptor binding" EXACT [GOC:mah] +is_a: GO:0070696 ! transmembrane receptor protein serine/threonine kinase binding +created_by: mah +creation_date: 2009-06-04T04:24:16Z + +[Term] +id: GO:0070701 +name: mucus layer +namespace: cellular_component +def: "An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes." [GOC:krc, GOC:mah, GOC:mm2, PMID:18806221, PMID:19432394, Wikipedia:Mucin] +synonym: "extracellular proteinaceous gel" BROAD [] +synonym: "mucous" EXACT [] +synonym: "mucous layer" EXACT [] +synonym: "mucus" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region +created_by: mah +creation_date: 2009-06-08T02:31:34Z + +[Term] +id: GO:0070702 +name: inner mucus layer +namespace: cellular_component +def: "The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria." [GOC:mah, GOC:mm2, PMID:18806221, PMID:19432394] +is_a: GO:0070701 ! mucus layer +created_by: mah +creation_date: 2009-06-08T02:38:55Z + +[Term] +id: GO:0070703 +name: outer mucus layer +namespace: cellular_component +def: "The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria." [GOC:mah, GOC:mm2, PMID:18806221, PMID:19432394] +is_a: GO:0070701 ! mucus layer +created_by: mah +creation_date: 2009-06-08T02:44:51Z + +[Term] +id: GO:0070704 +name: sterol desaturase activity +namespace: molecular_function +def: "Catalysis of the introduction of a double bond into a sterol molecule." [GOC:mah, GOC:vw] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: mah +creation_date: 2009-06-08T03:53:44Z + +[Term] +id: GO:0070705 +name: RNA nucleotide insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of one or more nucleotides." [GOC:cb, GOC:mah] +is_a: GO:0009451 ! RNA modification +created_by: mah +creation_date: 2009-06-08T04:48:35Z + +[Term] +id: GO:0070706 +name: RNA nucleotide deletion +namespace: biological_process +def: "The modification of an RNA molecule by removal of a single nucleotide." [GOC:cb, GOC:mah] +synonym: "RNA nucleotide excision" EXACT [GOC:cb, GOC:mah] +is_a: GO:0009451 ! RNA modification +created_by: mah +creation_date: 2009-06-08T04:50:51Z + +[Term] +id: GO:0070707 +name: RNA dinucleotide insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of a dinucleotide." [GOC:cb, GOC:mah] +is_a: GO:0070705 ! RNA nucleotide insertion +created_by: mah +creation_date: 2009-06-08T04:50:59Z + +[Term] +id: GO:0070708 +name: RNA cytidine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of a cytidine nucleotide." [GOC:cb, GOC:mah] +synonym: "RNA C insertion" EXACT [GOC:mah] +is_a: GO:0070705 ! RNA nucleotide insertion +created_by: mah +creation_date: 2009-06-08T04:52:49Z + +[Term] +id: GO:0070709 +name: RNA guanosine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of a guanosine nucleotide." [GOC:cb, GOC:mah] +synonym: "RNA G insertion" EXACT [GOC:mah] +is_a: GO:0070705 ! RNA nucleotide insertion +created_by: mah +creation_date: 2009-06-08T04:57:26Z + +[Term] +id: GO:0070710 +name: RNA uridine deletion +namespace: biological_process +def: "The modification of an RNA molecule by removal of a uridine nucleotide." [GOC:cb, GOC:mah] +synonym: "RNA U deletion" EXACT [GOC:mah] +synonym: "RNA uridine excision" EXACT [GOC:cb, GOC:mah] +is_a: GO:0070706 ! RNA nucleotide deletion +created_by: mah +creation_date: 2009-06-08T05:12:43Z + +[Term] +id: GO:0070711 +name: RNA adenosine-uridine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide." [GOC:cb, GOC:mah] +synonym: "RNA AU insertion" EXACT [GOC:mah] +is_a: GO:0070707 ! RNA dinucleotide insertion +created_by: mah +creation_date: 2009-06-08T05:16:39Z + +[Term] +id: GO:0070712 +name: RNA cytidine-uridine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide." [GOC:cb, GOC:mah] +synonym: "RNA CU insertion" EXACT [GOC:mah] +is_a: GO:0070707 ! RNA dinucleotide insertion +created_by: mah +creation_date: 2009-06-08T05:27:01Z + +[Term] +id: GO:0070713 +name: RNA guanosine-cytidine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide." [GOC:cb, GOC:mah] +synonym: "RNA GC insertion" EXACT [GOC:mah] +is_a: GO:0070707 ! RNA dinucleotide insertion +created_by: mah +creation_date: 2009-06-08T05:31:43Z + +[Term] +id: GO:0070714 +name: RNA guanosine-uridine insertion +namespace: biological_process +def: "The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide." [GOC:cb, GOC:mah] +synonym: "RNA GU insertion" EXACT [GOC:mah] +is_a: GO:0070707 ! RNA dinucleotide insertion +created_by: mah +creation_date: 2009-06-08T05:33:20Z + +[Term] +id: GO:0070715 +name: sodium-dependent organic cation transport +namespace: biological_process +def: "The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah] +is_a: GO:0015695 ! organic cation transport +created_by: mah +creation_date: 2009-06-09T03:26:27Z + +[Term] +id: GO:0070716 +name: mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication +namespace: biological_process +def: "A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication." [GOC:BHF, GOC:mah] +synonym: "mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication" RELATED [GOC:dph, GOC:tb] +is_a: GO:0006298 ! mismatch repair +intersection_of: GO:0006298 ! mismatch repair +intersection_of: part_of GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +relationship: part_of GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +created_by: mah +creation_date: 2009-06-09T04:00:29Z + +[Term] +id: GO:0070717 +name: poly-purine tract binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule." [GOC:mah] +is_a: GO:0003727 ! single-stranded RNA binding +created_by: mah +creation_date: 2009-06-10T03:32:15Z + +[Term] +id: GO:0070718 +name: alphaPDGFR-SHP-2 complex +namespace: cellular_component +def: "A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway." [GOC:mah, PMID:8943348] +synonym: "PDGFRA-SHP-2 complex, PDGF stimulated" NARROW [CORUM:3183] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-10T05:00:43Z + +[Term] +id: GO:0070719 +name: alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex +namespace: cellular_component +def: "A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway." [GOC:mah, PMID:8943348] +synonym: "PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated" NARROW [CORUM:2551] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-10T05:04:20Z + +[Term] +id: GO:0070720 +name: Grb2-SHP-2 complex +namespace: cellular_component +def: "A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway." [GOC:mah, PMID:8943348] +synonym: "GRB2-SHP-2 complex, PDGF stimulated" NARROW [CORUM:3186] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-10T05:08:21Z + +[Term] +id: GO:0070721 +name: ISGF3 complex +namespace: cellular_component +def: "A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein." [GOC:mah, PMID:8943351] +synonym: "interferon-stimulated gene factor 3 transcription complex" EXACT [CORUM:60] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2009-06-10T05:22:05Z + +[Term] +id: GO:0070722 +name: Tle3-Aes complex +namespace: cellular_component +def: "A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product." [GOC:mah, PMID:8955148] +synonym: "Grg3b-Grg5 complex" EXACT [CORUM:3130, PMID:8955148] +is_a: GO:0090571 ! RNA polymerase II transcription repressor complex +created_by: mah +creation_date: 2009-06-10T05:45:28Z + +[Term] +id: GO:0070723 +name: response to cholesterol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus." [GOC:BHF, GOC:vk] +is_a: GO:0036314 ! response to sterol +is_a: GO:0097305 ! response to alcohol +created_by: mah +creation_date: 2009-06-15T02:28:27Z + +[Term] +id: GO:0070724 +name: BMP receptor complex +namespace: cellular_component +def: "A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits." [GOC:mah, GOC:mh, PMID:19377468] +synonym: "bone morphogenetic protein receptor complex" EXACT [GOC:mah] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: mah +creation_date: 2009-06-15T02:34:27Z + +[Term] +id: GO:0070725 +name: Yb body +namespace: cellular_component +def: "A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell." [GOC:sart, PMID:19433453] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-06-15T05:17:28Z + +[Term] +id: GO:0070726 +name: cell wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells." [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0071555 ! cell wall organization +relationship: part_of GO:0042546 ! cell wall biogenesis +created_by: mah +creation_date: 2009-06-16T03:58:20Z + +[Term] +id: GO:0070727 +name: cellular macromolecule localization +namespace: biological_process +def: "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah] +synonym: "cellular macromolecule localisation" EXACT [GOC:mah] +is_a: GO:0033036 ! macromolecule localization +is_a: GO:0051641 ! cellular localization +created_by: mah +creation_date: 2009-06-16T04:08:29Z + +[Term] +id: GO:0070728 +name: leucine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid." [GOC:BHF, GOC:mah] +synonym: "Leu binding" EXACT [GOC:mah] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding +created_by: mah +creation_date: 2009-06-17T03:16:30Z + +[Term] +id: GO:0070729 +name: cyclic nucleotide transport +namespace: biological_process +def: "The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell." [GOC:mah, ISBN:0198506732] +is_a: GO:0006862 ! nucleotide transport +created_by: mah +creation_date: 2009-06-17T03:49:56Z + +[Term] +id: GO:0070730 +name: cAMP transport +namespace: biological_process +def: "The directed movement of cyclic AMP (cAMP), into, out of or within a cell." [GOC:mah, ISBN:0198506732] +synonym: "cyclic AMP transport" EXACT [GOC:mah] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:0070729 ! cyclic nucleotide transport +created_by: mah +creation_date: 2009-06-17T03:53:45Z + +[Term] +id: GO:0070731 +name: cGMP transport +namespace: biological_process +def: "The directed movement of cyclic GMP (cGMP), into, out of or within a cell." [GOC:mah, ISBN:0198506732] +synonym: "cyclic GMP transport" EXACT [GOC:mah] +is_a: GO:0001408 ! guanine nucleotide transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0070729 ! cyclic nucleotide transport +created_by: mah +creation_date: 2009-06-17T04:40:27Z + +[Term] +id: GO:0070732 +name: spindle envelope +namespace: cellular_component +def: "An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase." [GOC:mah, GOC:sart, PMID:19417004, PMID:6428889] +subset: goslim_candida +is_a: GO:0031967 ! organelle envelope +created_by: mah +creation_date: 2009-06-18T12:00:59Z + +[Term] +id: GO:0070733 +name: protein adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins." [GOC:mah, PMID:19039103, PMID:19362538] +synonym: "adenosine monophosphate-protein transferase activity" EXACT [GOC:mah] +synonym: "AMPylator" RELATED [GOC:mah] +xref: EC:2.7.7.n1 +is_a: GO:0070566 ! adenylyltransferase activity +relationship: part_of GO:0018117 ! protein adenylylation +created_by: mah +creation_date: 2009-06-18T01:09:15Z + +[Term] +id: GO:0070734 +name: histone H3-K27 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone." [GOC:mah, GOC:pr] +synonym: "histone H3 K27 methylation" EXACT [GOC:mah] +synonym: "histone H3K27me" EXACT [GOC:mah] +synonym: "histone lysine H3 K27 methylation" EXACT [GOC:mah] +is_a: GO:0034968 ! histone lysine methylation +created_by: mah +creation_date: 2009-06-19T11:44:37Z + +[Term] +id: GO:0070735 +name: protein-glycine ligase activity +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein." [GOC:mah, PMID:19524510] +synonym: "protein glycylase activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-8867370 "TTLL3, TTLL8, TTLL10 polyglycylate tubulin" +is_a: GO:0016881 ! acid-amino acid ligase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: mah +creation_date: 2009-06-19T01:51:21Z + +[Term] +id: GO:0070736 +name: protein-glycine ligase activity, initiating +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein." [GOC:mah, PMID:19524510] +synonym: "protein glycylase activity, initiating" EXACT [GOC:mah] +is_a: GO:0070735 ! protein-glycine ligase activity +created_by: mah +creation_date: 2009-06-19T01:56:32Z + +[Term] +id: GO:0070737 +name: protein-glycine ligase activity, elongating +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain." [GOC:mah, PMID:19524510] +synonym: "protein glycylase activity, elongating" EXACT [GOC:mah] +is_a: GO:0070735 ! protein-glycine ligase activity +created_by: mah +creation_date: 2009-06-19T02:00:21Z + +[Term] +id: GO:0070738 +name: tubulin-glycine ligase activity +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin." [GOC:mah, PMID:19524510] +synonym: "tubulin glycylase activity" EXACT [GOC:mah] +is_a: GO:0070735 ! protein-glycine ligase activity +created_by: mah +creation_date: 2009-06-19T02:02:01Z + +[Term] +id: GO:0070739 +name: protein-glutamic acid ligase activity +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein." [GOC:mah, PMID:19524510] +synonym: "protein glutamylase activity" EXACT [GOC:mah] +synonym: "protein-glutamate ligase activity" EXACT [GOC:mah] +is_a: GO:0016881 ! acid-amino acid ligase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: mah +creation_date: 2009-06-19T02:23:22Z + +[Term] +id: GO:0070740 +name: tubulin-glutamic acid ligase activity +namespace: molecular_function +def: "Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule." [GOC:mah, PMID:19524510] +synonym: "tubulin glutamylase activity" EXACT [GOC:mah] +synonym: "tubulin-glutamate ligase activity" EXACT [GOC:mah] +xref: Reactome:R-HSA-8865774 "TTLLs polyglutamylate tubulin" +xref: Reactome:R-HSA-8955869 "Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin" +is_a: GO:0070739 ! protein-glutamic acid ligase activity +created_by: mah +creation_date: 2009-06-19T02:26:15Z + +[Term] +id: GO:0070741 +name: response to interleukin-6 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus." [GOC:mah] +synonym: "response to IL-6" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-06-19T03:39:12Z + +[Term] +id: GO:0070742 +name: C2H2 zinc finger domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion." [GOC:BHF, GOC:mah, Pfam:PF00096] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2009-06-23T11:26:02Z + +[Term] +id: GO:0070743 +name: interleukin-23 complex +namespace: cellular_component +def: "A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space." [GOC:add, PMID:11114383, PMID:15999093] +comment: Note that this heterodimeric cytokine utilizes the same beta subunit as IL-12. +synonym: "IL-23 complex" EXACT [GOC:add] +synonym: "IL12B" NARROW [GOC:add] +synonym: "IL23A" NARROW [GOC:add] +synonym: "p19" NARROW [GOC:add] +synonym: "p40" NARROW [GOC:add] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: mah +creation_date: 2009-06-23T01:06:02Z + +[Term] +id: GO:0070744 +name: interleukin-27 complex +namespace: cellular_component +def: "A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space." [GOC:add, PMID:15999093, PMID:19161428] +comment: Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits. +synonym: "EBI3" NARROW [GOC:add] +synonym: "IL-27 complex" EXACT [GOC:add] +synonym: "IL27" NARROW [GOC:add] +synonym: "p28" NARROW [GOC:add] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: mah +creation_date: 2009-06-23T01:09:58Z + +[Term] +id: GO:0070745 +name: interleukin-35 complex +namespace: cellular_component +def: "A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space." [GOC:add, PMID:19161428, PMID:19161429] +comment: Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene. +synonym: "EBI3" NARROW [GOC:add] +synonym: "IL-35 complex" EXACT [GOC:add] +synonym: "IL12A" NARROW [GOC:add] +synonym: "p35" NARROW [GOC:add] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: mah +creation_date: 2009-06-23T01:13:14Z + +[Term] +id: GO:0070746 +name: interleukin-35 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with interleukin-35." [GOC:add] +synonym: "IL-35 binding" EXACT [GOC:add] +is_a: GO:0019955 ! cytokine binding +created_by: mah +creation_date: 2009-06-23T01:15:36Z + +[Term] +id: GO:0070747 +name: interleukin-35 receptor activity +namespace: molecular_function +def: "Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:add, GOC:signaling] +synonym: "IL-35 receptor activity" EXACT [GOC:add] +synonym: "IL-35R" EXACT [GOC:add] +is_a: GO:0004896 ! cytokine receptor activity +relationship: has_part GO:0070746 ! interleukin-35 binding +relationship: part_of GO:0070757 ! interleukin-35-mediated signaling pathway +created_by: mah +creation_date: 2009-06-23T01:18:09Z + +[Term] +id: GO:0070748 +name: interleukin-35 receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the interleukin-35 receptor." [GOC:add] +synonym: "IL-35" NARROW [GOC:add] +synonym: "interleukin-35 receptor ligand" NARROW [GOC:add] +is_a: GO:0005126 ! cytokine receptor binding +created_by: mah +creation_date: 2009-06-23T01:21:54Z + +[Term] +id: GO:0070749 +name: interleukin-35 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-35." [GOC:add] +synonym: "IL-35 biosynthesis" EXACT [GOC:mah] +synonym: "IL-35 biosynthetic process" EXACT [GOC:add] +synonym: "interleukin-35 anabolism" EXACT [GOC:mah] +synonym: "interleukin-35 biosynthesis" EXACT [GOC:mah] +synonym: "interleukin-35 formation" EXACT [GOC:mah] +synonym: "interleukin-35 synthesis" EXACT [GOC:mah] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0070753 ! interleukin-35 production +created_by: mah +creation_date: 2009-06-23T01:25:11Z + +[Term] +id: GO:0070750 +name: regulation of interleukin-35 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35." [GOC:add] +synonym: "regulation of IL-35 biosynthesis" EXACT [GOC:mah] +synonym: "regulation of IL-35 biosynthetic process" EXACT [GOC:add] +synonym: "regulation of interleukin-35 anabolism" EXACT [GOC:mah] +synonym: "regulation of interleukin-35 biosynthesis" EXACT [GOC:mah] +synonym: "regulation of interleukin-35 formation" EXACT [GOC:mah] +synonym: "regulation of interleukin-35 synthesis" EXACT [GOC:mah] +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +is_a: GO:0070754 ! regulation of interleukin-35 production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070749 ! interleukin-35 biosynthetic process +relationship: regulates GO:0070749 ! interleukin-35 biosynthetic process +created_by: mah +creation_date: 2009-06-23T01:29:17Z + +[Term] +id: GO:0070751 +name: negative regulation of interleukin-35 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35." [GOC:add] +synonym: "down regulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +synonym: "downregulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of interleukin-35 biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of IL-35 biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of IL-35 biosynthetic process" EXACT [GOC:add] +synonym: "negative regulation of interleukin-35 anabolism" EXACT [GOC:mah] +synonym: "negative regulation of interleukin-35 biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of interleukin-35 formation" EXACT [GOC:mah] +synonym: "negative regulation of interleukin-35 synthesis" EXACT [GOC:mah] +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0070750 ! regulation of interleukin-35 biosynthetic process +is_a: GO:0070755 ! negative regulation of interleukin-35 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070749 ! interleukin-35 biosynthetic process +relationship: negatively_regulates GO:0070749 ! interleukin-35 biosynthetic process +created_by: mah +creation_date: 2009-06-23T01:34:54Z + +[Term] +id: GO:0070752 +name: positive regulation of interleukin-35 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35." [GOC:add] +synonym: "activation of interleukin-35 biosynthetic process" NARROW [GOC:mah] +synonym: "positive regulation of IL-35 biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of IL-35 biosynthetic process" EXACT [GOC:add] +synonym: "positive regulation of interleukin-35 anabolism" EXACT [GOC:mah] +synonym: "positive regulation of interleukin-35 biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of interleukin-35 formation" EXACT [GOC:mah] +synonym: "positive regulation of interleukin-35 synthesis" EXACT [GOC:mah] +synonym: "stimulation of interleukin-35 biosynthetic process" NARROW [GOC:mah] +synonym: "up regulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +synonym: "up-regulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +synonym: "upregulation of interleukin-35 biosynthetic process" EXACT [GOC:mah] +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0070750 ! regulation of interleukin-35 biosynthetic process +is_a: GO:0070756 ! positive regulation of interleukin-35 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070749 ! interleukin-35 biosynthetic process +relationship: positively_regulates GO:0070749 ! interleukin-35 biosynthetic process +created_by: mah +creation_date: 2009-06-23T01:39:45Z + +[Term] +id: GO:0070753 +name: interleukin-35 production +namespace: biological_process +def: "The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah] +synonym: "IL-35 production" EXACT [GOC:add] +is_a: GO:0001816 ! cytokine production +created_by: mah +creation_date: 2009-06-23T01:42:04Z + +[Term] +id: GO:0070754 +name: regulation of interleukin-35 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of interleukin-35 production." [GOC:mah] +synonym: "regulation of IL-35 production" EXACT [GOC:add] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070753 ! interleukin-35 production +relationship: regulates GO:0070753 ! interleukin-35 production +created_by: mah +creation_date: 2009-06-23T01:44:37Z + +[Term] +id: GO:0070755 +name: negative regulation of interleukin-35 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production." [GOC:mah] +synonym: "down regulation of interleukin-35 production" EXACT [GOC:mah] +synonym: "down-regulation of interleukin-35 production" EXACT [GOC:mah] +synonym: "downregulation of interleukin-35 production" EXACT [GOC:mah] +synonym: "inhibition of interleukin-35 production" NARROW [GOC:mah] +synonym: "negative regulation of IL-35 production" EXACT [GOC:add] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0070754 ! regulation of interleukin-35 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070753 ! interleukin-35 production +relationship: negatively_regulates GO:0070753 ! interleukin-35 production +created_by: mah +creation_date: 2009-06-23T01:48:25Z + +[Term] +id: GO:0070756 +name: positive regulation of interleukin-35 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of interleukin-35 production." [GOC:mah] +synonym: "activation of interleukin-35 production" NARROW [GOC:mah] +synonym: "positive regulation of IL-35 production" EXACT [GOC:add] +synonym: "stimulation of interleukin-35 production" NARROW [GOC:mah] +synonym: "up regulation of interleukin-35 production" EXACT [GOC:mah] +synonym: "up-regulation of interleukin-35 production" EXACT [GOC:mah] +synonym: "upregulation of interleukin-35 production" EXACT [GOC:mah] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0070754 ! regulation of interleukin-35 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070753 ! interleukin-35 production +relationship: positively_regulates GO:0070753 ! interleukin-35 production +created_by: mah +creation_date: 2009-06-23T01:52:31Z + +[Term] +id: GO:0070757 +name: interleukin-35-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:add, GOC:mah, GOC:signaling] +synonym: "IL-35-mediated signaling pathway" EXACT [GOC:add] +synonym: "interleukin-35-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: mah +creation_date: 2009-06-23T01:55:02Z + +[Term] +id: GO:0070758 +name: regulation of interleukin-35-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor." [GOC:mah] +synonym: "regulation of IL-35-mediated signaling pathway" EXACT [GOC:mah] +synonym: "regulation of interleukin-35-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070757 ! interleukin-35-mediated signaling pathway +relationship: regulates GO:0070757 ! interleukin-35-mediated signaling pathway +created_by: mah +creation_date: 2009-06-23T01:58:43Z + +[Term] +id: GO:0070759 +name: negative regulation of interleukin-35-mediated signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor." [GOC:mah] +synonym: "negative regulation of IL-35-mediated signaling pathway" EXACT [GOC:add] +synonym: "negative regulation of interleukin-35-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:0070758 ! regulation of interleukin-35-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070757 ! interleukin-35-mediated signaling pathway +relationship: negatively_regulates GO:0070757 ! interleukin-35-mediated signaling pathway +created_by: mah +creation_date: 2009-06-23T02:02:07Z + +[Term] +id: GO:0070760 +name: positive regulation of interleukin-35-mediated signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor." [GOC:mah] +synonym: "positive regulation of IL-35-mediated signaling pathway" EXACT [GOC:add] +synonym: "positive regulation of interleukin-35-mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0070758 ! regulation of interleukin-35-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070757 ! interleukin-35-mediated signaling pathway +relationship: positively_regulates GO:0070757 ! interleukin-35-mediated signaling pathway +created_by: mah +creation_date: 2009-06-23T02:06:16Z + +[Term] +id: GO:0070761 +name: pre-snoRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes." [GOC:BHF, GOC:mah, GOC:rl, PMID:17636026, PMID:17709390] +synonym: "pre-small nucleolar ribonucleoprotein complex" EXACT [GOC:rl] +is_a: GO:1990904 ! ribonucleoprotein complex +created_by: mah +creation_date: 2009-06-23T02:32:10Z + +[Term] +id: GO:0070762 +name: nuclear pore transmembrane ring +namespace: cellular_component +def: "A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078] +synonym: "NDC1 complex" EXACT [] +synonym: "NDC1 subcomplex" EXACT [PMID:19414609] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005643 ! nuclear pore +created_by: mah +creation_date: 2009-06-29T11:02:56Z + +[Term] +id: GO:0070763 +name: Delta1 complex +namespace: cellular_component +def: "A protein complex that consists of homodimer of the Notch ligand Delta1." [PMID:12794186] +synonym: "Delta1 homodimer complex" EXACT [CORUM:3271] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T01:04:12Z + +[Term] +id: GO:0070764 +name: gamma-secretase-Delta1 complex +namespace: cellular_component +def: "A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex." [PMID:12794186] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T01:11:51Z + +[Term] +id: GO:0070765 +name: gamma-secretase complex +namespace: cellular_component +def: "A protein complex that has aspartic-type endopeptidase activity, and contains a catalytic subunit, presenilin (PS), that is a prototypical member of the GxGD-type aspartyl peptidases. The complex also contains additional subunits, including nicastrin, APH-1, PEN-2, and a regulatory subunit, CD147. Gamma-secretase cleaves several transmembrane proteins including the cell surface receptor Notch and the amyloid-beta precursor protein." [GOC:mah, PMID:15286082, PMID:15890777, PMID:17047368] +synonym: "CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)" NARROW [CORUM:142] +synonym: "gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant)" NARROW [CORUM:130, CORUM:2891, CORUM:43, CORUM:45, CORUM:466] +synonym: "gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)" NARROW [CORUM:468] +synonym: "gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)" RELATED [CORUM:3128] +synonym: "gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)" NARROW [CORUM:467] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T01:33:19Z + +[Term] +id: GO:0070766 +name: endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex +namespace: cellular_component +def: "A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof)." [PMID:8973549] +synonym: "SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)" NARROW [CORUM:1876] +synonym: "Stx4-Napa-Vamp3-Nsf-Vamp2 complex" NARROW [CORUM:1876] +is_a: GO:0031201 ! SNARE complex +created_by: mah +creation_date: 2009-06-29T04:41:55Z + +[Term] +id: GO:0070767 +name: BRCA1-Rad51 complex +namespace: cellular_component +def: "A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity." [GOC:mah, PMID:9008167] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2009-06-29T05:04:21Z + +[Term] +id: GO:0070768 +name: synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex +namespace: cellular_component +def: "A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof)." [PMID:8999968] +synonym: "Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex" NARROW [CORUM:1873] +synonym: "SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a)" NARROW [CORUM:1873] +is_a: GO:0031201 ! SNARE complex +created_by: mah +creation_date: 2009-06-29T05:14:04Z + +[Term] +id: GO:0070769 +name: alphaIIb-beta3 integrin-CIB complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin." [PMID:9030514] +synonym: "ITGA2B-ITGB3-CIB1 complex" NARROW [CORUM:2379] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T05:20:01Z + +[Term] +id: GO:0070770 +name: alphaIIb-beta3 integrin-CD47-FAK complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK." [PMID:9169439] +synonym: "ITGA2b-ITGB3-CD47-FAK complex" NARROW [CORUM:2896] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T05:43:59Z + +[Term] +id: GO:0070771 +name: alphaIIb-beta3 integrin-CD47-Src complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src." [PMID:9169439] +synonym: "ITGA2b-ITGB3-CD47-SRC complex" NARROW [CORUM:2377] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-06-29T05:46:53Z + +[Term] +id: GO:0070772 +name: PAS complex +namespace: cellular_component +def: "A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p." [PMID:18950639, PMID:19037259, PMID:19158662] +synonym: "autophagy-specific phosphatidylinositol 3-kinase complex" RELATED [PMID:24165940] +is_a: GO:0035032 ! phosphatidylinositol 3-kinase complex, class III +relationship: part_of GO:0005774 ! vacuolar membrane +created_by: mah +creation_date: 2009-06-30T11:13:32Z + +[Term] +id: GO:0070773 +name: protein-N-terminal glutamine amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein." [PMID:19560421] +synonym: "NtQ-amidase activity" EXACT [PMID:19560421] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: mah +creation_date: 2009-06-30T11:34:08Z + +[Term] +id: GO:0070774 +name: phytoceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine." [GOC:pde, PMID:11356846] +xref: KEGG_REACTION:R06528 +xref: MetaCyc:CERAMIDASE-YEAST-RXN +xref: Reactome:R-HSA-428262 "phytoceramide + H2O => stearate + phytosphingosine" +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +is_a: GO:0017040 ! N-acylsphingosine amidohydrolase activity +created_by: mah +creation_date: 2009-07-02T10:52:42Z + +[Term] +id: GO:0070775 +name: H3 histone acetyltransferase complex +namespace: cellular_component +def: "A multisubunit complex that catalyzes the acetylation of histone H3." [GOC:mah] +synonym: "H3 HAT complex" EXACT [GOC:mah] +is_a: GO:0000123 ! histone acetyltransferase complex +created_by: mah +creation_date: 2009-07-02T11:56:48Z + +[Term] +id: GO:0070776 +name: MOZ/MORF histone acetyltransferase complex +namespace: cellular_component +def: "A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3." [PMID:18794358] +is_a: GO:0070775 ! H3 histone acetyltransferase complex +created_by: mah +creation_date: 2009-07-02T12:06:04Z + +[Term] +id: GO:0070777 +name: D-aspartate transport +namespace: biological_process +def: "The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah, GOC:rph] +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0042940 ! D-amino acid transport +created_by: mah +creation_date: 2009-07-02T01:42:57Z + +[Term] +id: GO:0070778 +name: L-aspartate transmembrane transport +namespace: biological_process +alt_id: GO:0089712 +def: "The directed movement of L-aspartate across a membrane." [PMID:21307582] +synonym: "L-aspartate transport" BROAD [] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: mah +creation_date: 2009-07-02T01:46:31Z + +[Term] +id: GO:0070779 +name: D-aspartate import across plasma membrane +namespace: biological_process +alt_id: GO:0140016 +def: "The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol." [PMID:7914198] +synonym: "D-aspartate import" BROAD [] +synonym: "D-aspartate import into cell" EXACT [] +synonym: "D-aspartate uptake" EXACT [GOC:mah] +is_a: GO:0070777 ! D-aspartate transport +is_a: GO:0089718 ! amino acid import across plasma membrane +created_by: mah +creation_date: 2009-07-02T01:57:00Z + +[Term] +id: GO:0070780 +name: dihydrosphingosine-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate." [GOC:pde, PMID:12815058] +synonym: "dihydrosphingosine-1-phosphate phosphohydrolase activity" EXACT [GOC:mah] +synonym: "sphinganine-1-phosphate phosphatase activity" EXACT [GOC:mah] +xref: MetaCyc:RXN3DJ-25 +xref: Reactome:R-HSA-428664 "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate" +is_a: GO:0016791 ! phosphatase activity +created_by: mah +creation_date: 2009-07-02T02:13:49Z + +[Term] +id: GO:0070781 +name: response to biotin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus." [GOC:sl] +synonym: "response to Bios IIB" EXACT [GOC:sl] +synonym: "response to coenzyme R" EXACT [GOC:sl] +synonym: "response to vitamin B7" EXACT [GOC:sl] +synonym: "response to vitamin H" EXACT [GOC:sl] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033273 ! response to vitamin +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2009-07-02T02:34:43Z + +[Term] +id: GO:0070782 +name: phosphatidylserine exposure on apoptotic cell surface +namespace: biological_process +def: "A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity." [GOC:mah, GOC:mtg_apoptosis, GOC:rk, PMID:11536005] +comment: In normal cells, phosphatidylserine residues are found exclusively on the inner side of the cellular membrane. During apoptosis, phosphatidylserine is transported to the outer cell surface by scramblase proteins. This event acts as an "eat-me" signal for macrophages to dispose of the dying cell. When annotating to this term, curators should be aware of the following: 1) phosphatidylserine exposure on the cell surface can occur in circumstances other than apoptosis (for example, when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system, see PMID:21107324). Do not annotate to GO:0070782 unless phosphatidylserine exposure is shown to be part of an apoptotic event. 2) Caution should be applied when a study quotes annexin V assays. The annexin A5 protein binds to phosphatidylserine-containing membrane surfaces, which are usually only present on the inner leaflet of the membrane. However, in cells undergoing apoptosis, phosphatidylserine becomes exposed on the outer leaflet of the membrane. A positive annexin assay can therefore be linked to apoptotic death, but it shouldn't be confused with molecular events strictly involved in the process of phosphatidylserine exposure. +synonym: "externalization of phosphatidylserine" EXACT [GOC:rk] +is_a: GO:0017121 ! plasma membrane phospholipid scrambling +relationship: has_part GO:0017128 ! phospholipid scramblase activity +relationship: part_of GO:0097194 ! execution phase of apoptosis +created_by: mah +creation_date: 2009-07-02T02:41:44Z + +[Term] +id: GO:0070783 +name: growth of unicellular organism as a thread of attached cells +namespace: biological_process +def: "A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions." [GOC:mah, GOC:mcc] +subset: goslim_candida +is_a: GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: mah +creation_date: 2009-07-07T02:21:14Z + +[Term] +id: GO:0070784 +name: regulation of growth of unicellular organism as a thread of attached cells +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium." [GOC:mah] +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +relationship: regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +created_by: mah +creation_date: 2009-07-07T02:34:59Z + +[Term] +id: GO:0070785 +name: negative regulation of growth of unicellular organism as a thread of attached cells +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium." [GOC:mah] +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:1900429 ! negative regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +relationship: negatively_regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +created_by: mah +creation_date: 2009-07-07T02:37:21Z + +[Term] +id: GO:0070786 +name: positive regulation of growth of unicellular organism as a thread of attached cells +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium." [GOC:mah] +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +relationship: positively_regulates GO:0070783 ! growth of unicellular organism as a thread of attached cells +created_by: mah +creation_date: 2009-07-07T02:39:48Z + +[Term] +id: GO:0070787 +name: conidiophore development +namespace: biological_process +def: "The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores." [PMID:9529886] +is_a: GO:0075259 ! spore-bearing structure development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T01:30:36Z + +[Term] +id: GO:0070788 +name: conidiophore stalk development +namespace: biological_process +def: "The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop." [PMID:9529886] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0070787 ! conidiophore development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T01:31:44Z + +[Term] +id: GO:0070789 +name: metula development +namespace: biological_process +def: "The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip." [PMID:9529886] +synonym: "development of primary sterigmata" EXACT [PMID:9529886] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048468 ! cell development +relationship: part_of GO:0070787 ! conidiophore development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T01:33:46Z + +[Term] +id: GO:0070790 +name: phialide development +namespace: biological_process +def: "The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips." [PMID:9529886] +synonym: "development of secondary sterigmata" EXACT [PMID:9529886] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048468 ! cell development +relationship: part_of GO:0070787 ! conidiophore development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T02:32:30Z + +[Term] +id: GO:0070791 +name: cleistothecium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella." [ISBN:0471522295, PMID:17446882] +is_a: GO:0000909 ! sporocarp development involved in sexual reproduction +created_by: mah +creation_date: 2009-07-08T02:52:32Z + +[Term] +id: GO:0070792 +name: Hulle cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body." [PMID:19210625] +synonym: "Huelle cell development" EXACT [GOC:mah] +synonym: "Hulle cell formation" NARROW [PMID:19210625] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048468 ! cell development +relationship: part_of GO:0070791 ! cleistothecium development +created_by: mah +creation_date: 2009-07-08T02:54:30Z + +[Term] +id: GO:0070793 +name: regulation of conidiophore development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores." [GOC:mah] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070787 ! conidiophore development +relationship: regulates GO:0070787 ! conidiophore development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T03:04:29Z + +[Term] +id: GO:0070794 +name: negative regulation of conidiophore development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores." [GOC:mah] +is_a: GO:0070793 ! regulation of conidiophore development +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070787 ! conidiophore development +relationship: negatively_regulates GO:0070787 ! conidiophore development +created_by: mah +creation_date: 2009-07-08T03:06:48Z + +[Term] +id: GO:0070795 +name: positive regulation of conidiophore development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores." [GOC:mah] +is_a: GO:0070793 ! regulation of conidiophore development +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070787 ! conidiophore development +relationship: positively_regulates GO:0070787 ! conidiophore development +created_by: mah +creation_date: 2009-07-08T03:08:29Z + +[Term] +id: GO:0070796 +name: regulation of cleistothecium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella." [GOC:mah] +is_a: GO:1902058 ! regulation of sporocarp development involved in sexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070791 ! cleistothecium development +relationship: regulates GO:0070791 ! cleistothecium development +created_by: mah +creation_date: 2009-07-08T03:30:04Z + +[Term] +id: GO:0070797 +name: negative regulation of cleistothecium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella." [GOC:mah] +is_a: GO:0070796 ! regulation of cleistothecium development +is_a: GO:1902059 ! negative regulation of sporocarp development involved in sexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070791 ! cleistothecium development +relationship: negatively_regulates GO:0070791 ! cleistothecium development +created_by: mah +creation_date: 2009-07-08T03:36:12Z + +[Term] +id: GO:0070798 +name: positive regulation of cleistothecium development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella." [GOC:mah] +is_a: GO:0070796 ! regulation of cleistothecium development +is_a: GO:1902060 ! positive regulation of sporocarp development involved in sexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070791 ! cleistothecium development +relationship: positively_regulates GO:0070791 ! cleistothecium development +created_by: mah +creation_date: 2009-07-08T03:36:43Z + +[Term] +id: GO:0070799 +name: regulation of conidiophore stalk development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop." [GOC:mah] +is_a: GO:0070793 ! regulation of conidiophore development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070788 ! conidiophore stalk development +relationship: regulates GO:0070788 ! conidiophore stalk development +created_by: mah +creation_date: 2009-07-08T04:03:40Z + +[Term] +id: GO:0070800 +name: negative regulation of conidiophore stalk development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop." [GOC:mah] +is_a: GO:0070794 ! negative regulation of conidiophore development +is_a: GO:0070799 ! regulation of conidiophore stalk development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070788 ! conidiophore stalk development +relationship: negatively_regulates GO:0070788 ! conidiophore stalk development +created_by: mah +creation_date: 2009-07-08T04:10:42Z + +[Term] +id: GO:0070801 +name: positive regulation of conidiophore stalk development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop." [GOC:mah] +is_a: GO:0070795 ! positive regulation of conidiophore development +is_a: GO:0070799 ! regulation of conidiophore stalk development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070788 ! conidiophore stalk development +relationship: positively_regulates GO:0070788 ! conidiophore stalk development +created_by: mah +creation_date: 2009-07-08T04:11:22Z + +[Term] +id: GO:0070802 +name: regulation of metula development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip." [GOC:mah] +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0070793 ! regulation of conidiophore development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070789 ! metula development +relationship: regulates GO:0070789 ! metula development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T04:14:34Z + +[Term] +id: GO:0070803 +name: negative regulation of metula development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip." [GOC:mah] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0070794 ! negative regulation of conidiophore development +is_a: GO:0070802 ! regulation of metula development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070789 ! metula development +relationship: negatively_regulates GO:0070789 ! metula development +created_by: mah +creation_date: 2009-07-08T04:38:04Z + +[Term] +id: GO:0070804 +name: positive regulation of metula development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip." [GOC:mah] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0070795 ! positive regulation of conidiophore development +is_a: GO:0070802 ! regulation of metula development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070789 ! metula development +relationship: positively_regulates GO:0070789 ! metula development +created_by: mah +creation_date: 2009-07-08T04:38:33Z + +[Term] +id: GO:0070805 +name: regulation of phialide development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip." [GOC:mah] +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0070793 ! regulation of conidiophore development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070790 ! phialide development +relationship: regulates GO:0070790 ! phialide development +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: mah +creation_date: 2009-07-08T04:45:03Z + +[Term] +id: GO:0070806 +name: negative regulation of phialide development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip." [GOC:mah] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0070794 ! negative regulation of conidiophore development +is_a: GO:0070805 ! regulation of phialide development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070790 ! phialide development +relationship: negatively_regulates GO:0070790 ! phialide development +created_by: mah +creation_date: 2009-07-08T04:47:16Z + +[Term] +id: GO:0070807 +name: positive regulation of phialide development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip." [GOC:mah] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0070795 ! positive regulation of conidiophore development +is_a: GO:0070805 ! regulation of phialide development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070790 ! phialide development +relationship: positively_regulates GO:0070790 ! phialide development +created_by: mah +creation_date: 2009-07-08T04:48:08Z + +[Term] +id: GO:0070808 +name: regulation of Hulle cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body." [GOC:mah] +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0070796 ! regulation of cleistothecium development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070792 ! Hulle cell development +relationship: regulates GO:0070792 ! Hulle cell development +created_by: mah +creation_date: 2009-07-08T04:51:33Z + +[Term] +id: GO:0070809 +name: negative regulation of Hulle cell development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body." [GOC:mah] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0070797 ! negative regulation of cleistothecium development +is_a: GO:0070808 ! regulation of Hulle cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070792 ! Hulle cell development +relationship: negatively_regulates GO:0070792 ! Hulle cell development +created_by: mah +creation_date: 2009-07-08T04:53:11Z + +[Term] +id: GO:0070810 +name: positive regulation of Hulle cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body." [GOC:mah] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0070798 ! positive regulation of cleistothecium development +is_a: GO:0070808 ! regulation of Hulle cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070792 ! Hulle cell development +relationship: positively_regulates GO:0070792 ! Hulle cell development +created_by: mah +creation_date: 2009-07-08T04:54:12Z + +[Term] +id: GO:0070811 +name: glycerol-2-phosphate transmembrane transport +namespace: biological_process +def: "The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol." [GOC:mah] +synonym: "glycerol-2-phosphate transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015748 ! organophosphate ester transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901264 ! carbohydrate derivative transport +created_by: mah +creation_date: 2009-07-08T04:57:38Z + +[Term] +id: GO:0070812 +name: ATPase-coupled glycerol-2-phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-2-phosphate(out) = ADP + phosphate + glycerol-2-phosphate(in)." [GOC:mah] +synonym: "ATP-dependent glycerol-2-phosphate transmembrane transporter activity" EXACT [] +synonym: "glycerol-2-phosphate-transporting ATPase activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0070811 ! glycerol-2-phosphate transmembrane transport +created_by: mah +creation_date: 2009-07-08T05:01:33Z + +[Term] +id: GO:0070813 +name: hydrogen sulfide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hydrogen sulfide, H2S." [GOC:mah] +synonym: "hydrogen sulfide metabolism" EXACT [GOC:mah] +synonym: "hydrogen sulphide metabolic process" EXACT [GOC:mah] +synonym: "hydrogen sulphide metabolism" EXACT [GOC:mah] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0017144 ! drug metabolic process +created_by: mah +creation_date: 2009-07-09T10:37:32Z + +[Term] +id: GO:0070814 +name: hydrogen sulfide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S." [GOC:mah] +synonym: "hydrogen sulfide anabolism" EXACT [GOC:mah] +synonym: "hydrogen sulfide biosynthesis" EXACT [GOC:mah] +synonym: "hydrogen sulfide formation" EXACT [GOC:mah] +synonym: "hydrogen sulfide synthesis" EXACT [GOC:mah] +synonym: "hydrogen sulphide biosynthesis" EXACT [GOC:mah] +synonym: "hydrogen sulphide biosynthetic process" EXACT [GOC:mah] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0070813 ! hydrogen sulfide metabolic process +created_by: mah +creation_date: 2009-07-09T10:45:02Z + +[Term] +id: GO:0070815 +name: peptidyl-lysine 5-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2." [PMID:19574390] +synonym: "lysine hydroxylase activity" BROAD [GOC:mah] +synonym: "lysine,2-oxoglutarate 5-dioxygenase activity" BROAD [GOC:mah] +synonym: "lysine-2-oxoglutarate dioxygenase activity" BROAD [GOC:mah] +synonym: "lysyl hydroxylase activity" BROAD [GOC:mah] +synonym: "peptide-lysine 5-dioxygenase activity" EXACT [GOC:mah] +synonym: "peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity" EXACT [EC:1.14.11.4, GOC:mah] +synonym: "peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity" EXACT [EC:1.14.11.4, GOC:mah] +synonym: "protein lysine hydroxylase activity" EXACT [GOC:mah] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: mah +creation_date: 2009-07-09T11:42:07Z + +[Term] +id: GO:0070816 +name: phosphorylation of RNA polymerase II C-terminal domain +namespace: biological_process +alt_id: GO:0016245 +def: "The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex." [GOC:krc, GOC:mah, PMID:17079683] +synonym: "CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:mah] +synonym: "generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:krc] +synonym: "generation of II(0) form of RNA polymerase II" EXACT [GOC:krc] +synonym: "hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:krc] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0006468 ! protein phosphorylation +created_by: mah +creation_date: 2009-07-13T04:01:19Z + +[Term] +id: GO:0070817 +name: P-TEFb-cap methyltransferase complex localization +namespace: biological_process +def: "Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of P-TEFb-cap methyltransferase complex localization" EXACT [GOC:MAH] +synonym: "P-TEFb-cap methyltransferase complex localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization +created_by: mah +creation_date: 2009-07-13T04:20:17Z + +[Term] +id: GO:0070818 +name: protoporphyrinogen oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor." [EC:1.3.3.4, GOC:mah, PMID:19583219] +synonym: "protoporphyrinogen IX oxidase activity" EXACT [EC:1.3.3.4] +synonym: "protoporphyrinogen-IX oxidase activity" EXACT [EC:1.3.3.4] +synonym: "protoporphyrinogenase activity" EXACT [EC:1.3.3.4] +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors +created_by: mah +creation_date: 2009-07-20T02:41:12Z + +[Term] +id: GO:0070819 +name: menaquinone-dependent protoporphyrinogen oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone." [GOC:mah, PMID:19583219] +synonym: "protoporphyrinogen-IX:menaquinone oxidoreductase activity" EXACT [GOC:mah] +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor +is_a: GO:0070818 ! protoporphyrinogen oxidase activity +created_by: mah +creation_date: 2009-07-20T02:46:06Z + +[Term] +id: GO:0070820 +name: tertiary granule +namespace: cellular_component +def: "A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells." [GOC:BHF, GOC:mah, GOC:rl, PMID:12070036] +synonym: "gelatinase granule" EXACT [PMID:23650620] +is_a: GO:0030141 ! secretory granule +created_by: mah +creation_date: 2009-07-20T03:57:00Z + +[Term] +id: GO:0070821 +name: tertiary granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a tertiary granule." [GOC:BHF, GOC:mah, GOC:rl, PMID:12070036] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0070820 ! tertiary granule +created_by: mah +creation_date: 2009-07-20T03:59:41Z + +[Term] +id: GO:0070822 +name: Sin3-type complex +namespace: cellular_component +def: "Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex." [PMID:15565322, PMID:18292778] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin +created_by: mah +creation_date: 2009-07-20T04:32:33Z + +[Term] +id: GO:0070823 +name: HDA1 complex +namespace: cellular_component +def: "A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p." [GOC:dgf, GOC:mah, PMID:11287668, PMID:8663039] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin +created_by: mah +creation_date: 2009-07-20T04:47:11Z + +[Term] +id: GO:0070824 +name: SHREC complex +namespace: cellular_component +def: "A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures." [GOC:mah, PMID:17289569] +is_a: GO:0000118 ! histone deacetylase complex +is_a: GO:0017053 ! transcription repressor complex +created_by: mah +creation_date: 2009-07-20T05:02:12Z + +[Term] +id: GO:0070825 +name: micropyle +namespace: cellular_component +def: "An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization." [GOC:cvs, GOC:mah, PMID:18649270] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0042600 ! egg chorion +created_by: mah +creation_date: 2009-07-21T05:33:09Z + +[Term] +id: GO:0070826 +name: paraferritin complex +namespace: cellular_component +def: "A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme." [GOC:mah, GOC:rph, PMID:11842004, PMID:8639593] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-07-23T03:05:08Z + +[Term] +id: GO:0070827 +name: chromatin maintenance +namespace: biological_process +def: "The chromatin organization process that preserves chromatin in a stable functional or structural state." [GOC:mah] +is_a: GO:0006325 ! chromatin organization +is_a: GO:0043954 ! cellular component maintenance +created_by: mah +creation_date: 2009-07-23T04:09:59Z + +[Term] +id: GO:0070828 +name: heterochromatin organization +namespace: biological_process +def: "Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin." [GOC:mah] +synonym: "heterochromatin organisation" EXACT [GOC:mah] +is_a: GO:0006325 ! chromatin organization +created_by: mah +creation_date: 2009-07-23T04:12:48Z + +[Term] +id: GO:0070829 +name: heterochromatin maintenance +namespace: biological_process +alt_id: GO:0006344 +alt_id: GO:0070870 +def: "The chromatin organization process that preserves heterochromatin in a stable functional or structural state." [GOC:mah] +synonym: "heterochromatin maintenance involved in chromatin silencing" RELATED [] +synonym: "maintenance of chromatin silencing" RELATED [] +synonym: "maintenance of heterochromatic silencing" RELATED [] +is_a: GO:0051276 ! chromosome organization +is_a: GO:0070827 ! chromatin maintenance +is_a: GO:0070868 ! heterochromatin organization involved in chromatin silencing +created_by: mah +creation_date: 2009-07-23T04:14:49Z + +[Term] +id: GO:0070830 +name: bicellular tight junction assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet." [GOC:mah] +synonym: "tight junction formation" EXACT [GOC:mah] +is_a: GO:0120192 ! tight junction assembly +relationship: part_of GO:0043297 ! apical junction assembly +created_by: mah +creation_date: 2009-07-23T04:32:38Z + +[Term] +id: GO:0070831 +name: basement membrane assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah] +comment: Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer. +is_a: GO:0071711 ! basement membrane organization +is_a: GO:0085029 ! extracellular matrix assembly +created_by: mah +creation_date: 2009-07-23T05:01:51Z + +[Term] +id: GO:0070832 +name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine." [MetaCyc:PWY4FS-2] +xref: MetaCyc:PWY4FS-2 +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: mah +creation_date: 2009-07-29T03:49:14Z + +[Term] +id: GO:0070833 +name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine." [MetaCyc:PWY4FS-3] +xref: MetaCyc:PWY4FS-3 +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +is_a: GO:1901160 ! primary amino compound metabolic process +created_by: mah +creation_date: 2009-07-29T03:51:39Z + +[Term] +id: GO:0070834 +name: phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine." [MetaCyc:PWY4FS-4] +xref: MetaCyc:PWY4FS-4 +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: mah +creation_date: 2009-07-29T03:54:47Z + +[Term] +id: GO:0070835 +name: chromium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of chromium (Cr) ions from one side of a membrane to the other." [GOC:mah, GOC:yaf] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +created_by: mah +creation_date: 2009-07-30T03:04:09Z + +[Term] +id: GO:0070836 +name: caveola assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane." [GOC:BHF, GOC:mah, GOC:vk, PMID:12633858] +synonym: "caveola formation" EXACT [GOC:mah] +synonym: "caveolar biogenesis" RELATED [PMID:12633858] +is_a: GO:0044854 ! plasma membrane raft assembly +created_by: mah +creation_date: 2009-07-30T04:45:54Z + +[Term] +id: GO:0070837 +name: dehydroascorbic acid transport +namespace: biological_process +def: "The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C." [GOC:sl] +synonym: "dehydroascorbate transport" EXACT [GOC:sl] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0051180 ! vitamin transport +created_by: mah +creation_date: 2009-07-30T05:24:31Z + +[Term] +id: GO:0070838 +name: divalent metal ion transport +namespace: biological_process +def: "The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0030001 ! metal ion transport +is_a: GO:0072511 ! divalent inorganic cation transport +created_by: mah +creation_date: 2009-07-31T01:02:39Z + +[Term] +id: GO:0070839 +name: divalent metal ion export +namespace: biological_process +def: "The directed movement of divalent metal cations, any metal ion with a +2 electric charge, out of a cell or organelle." [GOC:mah] +is_a: GO:0070838 ! divalent metal ion transport +created_by: mah +creation_date: 2009-07-31T01:07:46Z + +[Term] +id: GO:0070840 +name: dynein complex binding +namespace: molecular_function +alt_id: GO:0045502 +def: "Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity." [GOC:bf, GOC:BHF, GOC:mah] +synonym: "dynein binding" RELATED [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2009-07-31T01:22:47Z + +[Term] +id: GO:0070841 +name: inclusion body assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an inclusion body." [GOC:BHF, GOC:mah] +is_a: GO:0022607 ! cellular component assembly +created_by: mah +creation_date: 2009-07-31T01:28:14Z + +[Term] +id: GO:0070842 +name: aggresome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein." [GOC:BHF, GOC:rl, PMID:14675537] +is_a: GO:0070841 ! inclusion body assembly +created_by: mah +creation_date: 2009-07-31T01:30:25Z + +[Term] +id: GO:0070843 +name: misfolded protein transport +namespace: biological_process +def: "The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell." [GOC:BHF, GOC:mah, PMID:14675537] +is_a: GO:0006886 ! intracellular protein transport +created_by: mah +creation_date: 2009-07-31T12:50:00Z + +[Term] +id: GO:0070844 +name: polyubiquitinated protein transport +namespace: biological_process +def: "The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell." [GOC:BHF, GOC:mah, PMID:14675537] +synonym: "polyubiquitylated protein transport" EXACT [GOC:mah] +is_a: GO:0006886 ! intracellular protein transport +created_by: mah +creation_date: 2009-07-31T12:51:10Z + +[Term] +id: GO:0070845 +name: polyubiquitinated misfolded protein transport +namespace: biological_process +def: "The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell." [GOC:BHF, GOC:mah, PMID:14675537] +synonym: "misfolded polyubiquitinated protein transport" RELATED [GOC:mah] +synonym: "polyubiquitylated misfolded protein transport" EXACT [GOC:mah] +is_a: GO:0070843 ! misfolded protein transport +is_a: GO:0070844 ! polyubiquitinated protein transport +created_by: mah +creation_date: 2009-07-31T12:52:26Z + +[Term] +id: GO:0070846 +name: Hsp90 deacetylation +namespace: biological_process +def: "The modification of an Hsp90 protein by removal of acetyl groups." [GOC:BHF, GOC:mah] +is_a: GO:0006476 ! protein deacetylation +created_by: mah +creation_date: 2009-07-31T12:58:47Z + +[Term] +id: GO:0070847 +name: core mediator complex +namespace: cellular_component +def: "A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins." [PMID:11454195, PMID:16168358, PMID:17870225] +synonym: "C mediator complex" EXACT [PMID:17870225] +synonym: "S mediator complex" EXACT [PMID:17043218] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15979 xsd:anyURI +created_by: mah +creation_date: 2009-08-04T02:56:11Z + +[Term] +id: GO:0070848 +name: response to growth factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." [GOC:BHF, GOC:mah] +synonym: "response to growth factor stimulus" EXACT [GOC:dos] +is_a: GO:0010033 ! response to organic substance +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: mah +creation_date: 2009-08-04T04:24:18Z + +[Term] +id: GO:0070849 +name: response to epidermal growth factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus." [GOC:BHF, GOC:mah] +synonym: "response to EGF stimulus" EXACT [GOC:mah] +synonym: "response to epidermal growth factor stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: mah +creation_date: 2009-08-04T04:26:26Z + +[Term] +id: GO:0070850 +name: TACC/TOG complex +namespace: cellular_component +def: "A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase." [GOC:mah, GOC:vw, PMID:19606211] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-08-05T03:06:08Z + +[Term] +id: GO:0070851 +name: growth factor receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a growth factor receptor." [GOC:mah, GOC:vw] +is_a: GO:0005102 ! signaling receptor binding +created_by: mah +creation_date: 2009-08-07T11:23:02Z + +[Term] +id: GO:0070852 +name: cell body fiber +namespace: cellular_component +def: "A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches." [GOC:dos, GOC:mah] +synonym: "cell body fibre" EXACT [] +synonym: "primary neurite" RELATED [GOC:dos, GOC:mah] +is_a: GO:0043005 ! neuron projection +created_by: mah +creation_date: 2009-08-11T04:38:53Z + +[Term] +id: GO:0070853 +name: myosin VI binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:15473855] +is_a: GO:0017022 ! myosin binding +created_by: mah +creation_date: 2009-08-13T01:28:36Z + +[Term] +id: GO:0070854 +name: myosin VI heavy chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a heavy chain of a myosin VI complex." [GOC:sart] +is_a: GO:0032036 ! myosin heavy chain binding +is_a: GO:0070853 ! myosin VI binding +created_by: mah +creation_date: 2009-08-13T01:44:05Z + +[Term] +id: GO:0070855 +name: myosin VI head/neck binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the head/neck region of a myosin VI heavy chain." [GOC:sart] +is_a: GO:0032028 ! myosin head/neck binding +is_a: GO:0070854 ! myosin VI heavy chain binding +created_by: mah +creation_date: 2009-08-13T01:45:08Z + +[Term] +id: GO:0070856 +name: myosin VI light chain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a light chain of a myosin VI complex." [GOC:sart] +is_a: GO:0032027 ! myosin light chain binding +is_a: GO:0070853 ! myosin VI binding +created_by: mah +creation_date: 2009-08-13T01:46:13Z + +[Term] +id: GO:0070857 +name: regulation of bile acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] +synonym: "regulation of bile acid anabolism" EXACT [GOC:mah] +synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah] +synonym: "regulation of bile acid formation" EXACT [GOC:mah] +synonym: "regulation of bile acid synthesis" EXACT [GOC:mah] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +is_a: GO:1904251 ! regulation of bile acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006699 ! bile acid biosynthetic process +relationship: regulates GO:0006699 ! bile acid biosynthetic process +created_by: mah +creation_date: 2009-08-14T03:09:02Z + +[Term] +id: GO:0070858 +name: negative regulation of bile acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] +synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah] +synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of bile acid biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah] +synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of bile acid formation" EXACT [GOC:mah] +synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0070857 ! regulation of bile acid biosynthetic process +is_a: GO:1904252 ! negative regulation of bile acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006699 ! bile acid biosynthetic process +relationship: negatively_regulates GO:0006699 ! bile acid biosynthetic process +created_by: mah +creation_date: 2009-08-14T03:16:40Z + +[Term] +id: GO:0070859 +name: positive regulation of bile acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] +synonym: "activation of bile acid biosynthetic process" NARROW [GOC:mah] +synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah] +synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of bile acid formation" EXACT [GOC:mah] +synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah] +synonym: "stimulation of bile acid biosynthetic process" NARROW [GOC:mah] +synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah] +synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah] +synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0070857 ! regulation of bile acid biosynthetic process +is_a: GO:1904253 ! positive regulation of bile acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006699 ! bile acid biosynthetic process +relationship: positively_regulates GO:0006699 ! bile acid biosynthetic process +created_by: mah +creation_date: 2009-08-14T03:22:58Z + +[Term] +id: GO:0070860 +name: RNA polymerase I core factor complex +namespace: cellular_component +def: "A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p." [PMID:8702872] +comment: Note that, although this complex can be considered analogous to the mammalian transcription factor SL complex, the core factor complex does not include TBP, whereas SL1 does. +is_a: GO:0000120 ! RNA polymerase I transcription regulator complex +created_by: mah +creation_date: 2009-08-14T05:00:44Z + +[Term] +id: GO:0070861 +name: regulation of protein exit from endoplasmic reticulum +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum." [GOC:mah] +synonym: "regulation of protein exit from ER" EXACT [GOC:mah] +synonym: "regulation of protein export from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "regulation of protein export from ER" EXACT [GOC:mah] +is_a: GO:0033157 ! regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032527 ! protein exit from endoplasmic reticulum +relationship: regulates GO:0032527 ! protein exit from endoplasmic reticulum +created_by: mah +creation_date: 2009-08-17T03:39:18Z + +[Term] +id: GO:0070862 +name: negative regulation of protein exit from endoplasmic reticulum +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum." [GOC:mah] +synonym: "down regulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "down-regulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "downregulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "inhibition of protein exit from endoplasmic reticulum" NARROW [GOC:mah] +synonym: "negative regulation of protein exit from ER" EXACT [GOC:mah] +synonym: "negative regulation of protein export from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "negative regulation of protein export from ER" EXACT [GOC:mah] +is_a: GO:0070861 ! regulation of protein exit from endoplasmic reticulum +is_a: GO:0090317 ! negative regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032527 ! protein exit from endoplasmic reticulum +relationship: negatively_regulates GO:0032527 ! protein exit from endoplasmic reticulum +created_by: mah +creation_date: 2009-08-17T03:45:56Z + +[Term] +id: GO:0070863 +name: positive regulation of protein exit from endoplasmic reticulum +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum." [GOC:mah] +synonym: "activation of protein exit from endoplasmic reticulum" NARROW [GOC:mah] +synonym: "positive regulation of protein exit from ER" EXACT [GOC:mah] +synonym: "positive regulation of protein export from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "positive regulation of protein export from ER" EXACT [GOC:mah] +synonym: "stimulation of protein exit from endoplasmic reticulum" NARROW [GOC:mah] +synonym: "up regulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "up-regulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +synonym: "upregulation of protein exit from endoplasmic reticulum" EXACT [GOC:mah] +is_a: GO:0070861 ! regulation of protein exit from endoplasmic reticulum +is_a: GO:0090316 ! positive regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032527 ! protein exit from endoplasmic reticulum +relationship: positively_regulates GO:0032527 ! protein exit from endoplasmic reticulum +created_by: mah +creation_date: 2009-08-17T03:50:04Z + +[Term] +id: GO:0070864 +name: sperm individualization complex +namespace: cellular_component +def: "A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst." [GOC:sart, PMID:10588662, PMID:9550716] +is_a: GO:0032991 ! protein-containing complex +created_by: mah +creation_date: 2009-08-19T01:25:33Z + +[Term] +id: GO:0070865 +name: investment cone +namespace: cellular_component +def: "A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization." [GOC:sart, PMID:15829565, PMID:9550716] +synonym: "F-actin cone" EXACT [PMID:15829565] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +relationship: part_of GO:0070864 ! sperm individualization complex +created_by: mah +creation_date: 2009-08-19T01:29:33Z + +[Term] +id: GO:0070866 +name: sterol-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) in the presence of sterols." [GOC:ecd] +is_a: GO:0005515 ! protein binding +created_by: mah +creation_date: 2009-08-19T01:43:35Z + +[Term] +id: GO:0070867 +name: mating projection tip membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a mating projection tip." [GOC:mah] +synonym: "mating projection membrane fusion domain" EXACT [PMID:29134248] +synonym: "shmoo tip membrane" NARROW [GOC:mah] +is_a: GO:0031520 ! plasma membrane of cell tip +intersection_of: GO:0098590 ! plasma membrane region +intersection_of: part_of GO:0043332 ! mating projection tip +relationship: part_of GO:0043332 ! mating projection tip +created_by: mah +creation_date: 2009-08-19T04:05:58Z + +[Term] +id: GO:0070868 +name: heterochromatin organization involved in chromatin silencing +namespace: biological_process +def: "Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing." [GOC:mah] +synonym: "heterochromatin organisation involved in chromatin silencing" EXACT [GOC:mah] +is_a: GO:0070828 ! heterochromatin organization +is_a: GO:0097549 ! chromatin organization involved in negative regulation of transcription +intersection_of: GO:0070828 ! heterochromatin organization +intersection_of: part_of GO:0006342 ! chromatin silencing +relationship: part_of GO:0006342 ! chromatin silencing +created_by: mah +creation_date: 2009-08-20T12:45:52Z + +[Term] +id: GO:0070871 +name: cell wall organization involved in conjugation with cellular fusion +namespace: biological_process +def: "A process of cell wall organization that contributes to conjugation with cellular fusion." [GOC:mah] +synonym: "cell wall organisation involved in conjugation with cellular fusion" EXACT [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0071555 ! cell wall organization +intersection_of: GO:0071555 ! cell wall organization +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2009-08-20T02:23:19Z + +[Term] +id: GO:0070873 +name: regulation of glycogen metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] +synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005977 ! glycogen metabolic process +relationship: regulates GO:0005977 ! glycogen metabolic process +created_by: mah +creation_date: 2009-08-20T02:44:53Z + +[Term] +id: GO:0070874 +name: negative regulation of glycogen metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] +synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0070873 ! regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005977 ! glycogen metabolic process +relationship: negatively_regulates GO:0005977 ! glycogen metabolic process +created_by: mah +creation_date: 2009-08-20T02:50:41Z + +[Term] +id: GO:0070875 +name: positive regulation of glycogen metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] +synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010907 ! positive regulation of glucose metabolic process +is_a: GO:0070873 ! regulation of glycogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005977 ! glycogen metabolic process +relationship: positively_regulates GO:0005977 ! glycogen metabolic process +created_by: mah +creation_date: 2009-08-20T02:53:55Z + +[Term] +id: GO:0070876 +name: SOSS complex +namespace: cellular_component +def: "A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80." [PMID:19683501] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2009-08-20T03:30:48Z + +[Term] +id: GO:0070877 +name: microprocessor complex +namespace: cellular_component +def: "A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs." [PMID:16963499, PMID:17159994] +xref: IntAct:EBI-9519039 +xref: IntAct:EBI-9519056 +is_a: GO:1903095 ! ribonuclease III complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2009-08-20T03:56:26Z + +[Term] +id: GO:0070878 +name: primary miRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding." [GOC:sl, PMID:15531877, PMID:15574589] +synonym: "pri-miRNA binding" EXACT [] +synonym: "primary microRNA binding" EXACT [PMID:15531877, PMID:15574589] +is_a: GO:0003723 ! RNA binding +created_by: mah +creation_date: 2009-08-20T04:11:36Z + +[Term] +id: GO:0070879 +name: fungal-type cell wall beta-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells." [GOC:mah, GOC:vw] +synonym: "fungal-type cell wall beta-glucan metabolism" EXACT [GOC:mah] +is_a: GO:0034406 ! cell wall beta-glucan metabolic process +is_a: GO:0071966 ! fungal-type cell wall polysaccharide metabolic process +relationship: part_of GO:0009272 ! fungal-type cell wall biogenesis +created_by: mah +creation_date: 2009-08-21T02:46:09Z + +[Term] +id: GO:0070880 +name: fungal-type cell wall beta-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells." [GOC:mah] +synonym: "fungal-type cell wall beta-glucan anabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-glucan biosynthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-glucan formation" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0034410 ! cell wall beta-glucan biosynthetic process +is_a: GO:0051278 ! fungal-type cell wall polysaccharide biosynthetic process +is_a: GO:0070879 ! fungal-type cell wall beta-glucan metabolic process +created_by: mah +creation_date: 2009-08-21T02:48:24Z + +[Term] +id: GO:0070881 +name: regulation of proline transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proline transport." [GOC:mah] +is_a: GO:0051955 ! regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015824 ! proline transport +relationship: regulates GO:0015824 ! proline transport +created_by: mah +creation_date: 2009-08-21T04:48:34Z + +[Term] +id: GO:0070883 +name: pre-miRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA." [PMID:18951094] +synonym: "pre-microRNA binding" EXACT [GOC:pr] +synonym: "precursor microRNA binding" EXACT [PMID:18951094] +is_a: GO:0003723 ! RNA binding +created_by: mah +creation_date: 2009-08-24T04:36:24Z + +[Term] +id: GO:0070884 +name: regulation of calcineurin-NFAT signaling cascade +namespace: biological_process +alt_id: GO:0051531 +alt_id: GO:0051532 +def: "Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade." [GOC:ai] +synonym: "NFAT protein import into nucleus" NARROW [] +synonym: "regulation of calcineurin-NFAT signaling pathway" RELATED [GOC:bf] +synonym: "regulation of calcineurin-NFAT signalling cascade" EXACT [GOC:mah] +synonym: "regulation of NFAT protein import into nucleus" NARROW [] +is_a: GO:0106056 ! regulation of calcineurin-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033173 ! calcineurin-NFAT signaling cascade +relationship: regulates GO:0033173 ! calcineurin-NFAT signaling cascade +created_by: mah +creation_date: 2009-08-26T03:25:30Z + +[Term] +id: GO:0070885 +name: negative regulation of calcineurin-NFAT signaling cascade +namespace: biological_process +alt_id: GO:0051534 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade." [GOC:mah] +synonym: "down regulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +synonym: "down-regulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +synonym: "downregulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +synonym: "inhibition of calcineurin-NFAT signaling cascade" NARROW [GOC:mah] +synonym: "inhibition of NFAT protein import into nucleus" NARROW [] +synonym: "negative regulation of calcineurin-NFAT signaling pathway" RELATED [GOC:bf] +synonym: "negative regulation of calcineurin-NFAT signalling cascade" EXACT [GOC:mah] +synonym: "negative regulation of NFAT protein import into nucleus" NARROW [] +synonym: "termination of calcineurin-NFAT signaling cascade" NARROW [GOC:bf] +is_a: GO:0070884 ! regulation of calcineurin-NFAT signaling cascade +is_a: GO:0106057 ! negative regulation of calcineurin-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033173 ! calcineurin-NFAT signaling cascade +relationship: negatively_regulates GO:0033173 ! calcineurin-NFAT signaling cascade +created_by: mah +creation_date: 2009-08-26T03:29:33Z + +[Term] +id: GO:0070886 +name: positive regulation of calcineurin-NFAT signaling cascade +namespace: biological_process +alt_id: GO:0051533 +def: "Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade." [GOC:mah] +synonym: "activation of calcineurin-NFAT signaling cascade" NARROW [GOC:mah] +synonym: "positive regulation of calcineurin-NFAT signaling pathway" RELATED [GOC:bf] +synonym: "positive regulation of calcineurin-NFAT signalling cascade" EXACT [GOC:mah] +synonym: "positive regulation of NFAT protein import into nucleus" NARROW [] +synonym: "stimulation of calcineurin-NFAT signaling cascade" NARROW [GOC:mah] +synonym: "up regulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +synonym: "up-regulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +synonym: "upregulation of calcineurin-NFAT signaling cascade" EXACT [GOC:mah] +is_a: GO:0070884 ! regulation of calcineurin-NFAT signaling cascade +is_a: GO:0106058 ! positive regulation of calcineurin-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033173 ! calcineurin-NFAT signaling cascade +relationship: positively_regulates GO:0033173 ! calcineurin-NFAT signaling cascade +created_by: mah +creation_date: 2009-08-26T03:37:10Z + +[Term] +id: GO:0070887 +name: cellular response to chemical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0042221 ! response to chemical +is_a: GO:0051716 ! cellular response to stimulus +created_by: mah +creation_date: 2009-08-27T04:41:45Z + +[Term] +id: GO:0070888 +name: E-box binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues." [GOC:BHF, GOC:vk, PMID:11812799] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "E-box promoter binding" EXACT [GOC:vk] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: mah +creation_date: 2009-08-28T10:37:01Z + +[Term] +id: GO:0070889 +name: platelet alpha granule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets." [GOC:rph, PMID:16123220] +synonym: "platelet alpha granule organisation" EXACT [GOC:mah] +synonym: "platelet alpha granule organization and biogenesis" RELATED [GOC:mah] +synonym: "platelet alpha-granule organization" EXACT [GOC:mah] +is_a: GO:0033363 ! secretory granule organization +created_by: mah +creation_date: 2009-08-28T10:43:31Z + +[Term] +id: GO:0070890 +name: sodium-dependent L-ascorbate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in)." [GOC:mah, GOC:yaf, PMID:18094143] +is_a: GO:0008520 ! L-ascorbate:sodium symporter activity +created_by: mah +creation_date: 2009-09-01T02:25:22Z + +[Term] +id: GO:0070891 +name: lipoteichoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipoteichoic acid." [GOC:add, PMID:14665680] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: mah +creation_date: 2009-09-01T02:56:36Z + +[Term] +id: GO:0070892 +name: lipoteichoic acid immune receptor activity +namespace: molecular_function +def: "Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response." [GOC:add, PMID:14665680] +synonym: "lipoteichoic acid receptor activity" BROAD [] +is_a: GO:0038187 ! pattern recognition receptor activity +relationship: has_part GO:0070891 ! lipoteichoic acid binding +created_by: mah +creation_date: 2009-09-01T02:59:24Z + +[Term] +id: GO:0070893 +name: transposon integration +namespace: biological_process +def: "Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome." [GOC:jp, PMID:10882723] +is_a: GO:0015074 ! DNA integration +is_a: GO:0032196 ! transposition +created_by: mah +creation_date: 2009-09-01T04:08:19Z + +[Term] +id: GO:0070894 +name: regulation of transposon integration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule." [GOC:mah] +is_a: GO:0010528 ! regulation of transposition +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070893 ! transposon integration +relationship: regulates GO:0070893 ! transposon integration +created_by: mah +creation_date: 2009-09-01T04:14:09Z + +[Term] +id: GO:0070895 +name: negative regulation of transposon integration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule." [GOC:mah] +synonym: "down regulation of transposon integration" EXACT [GOC:mah] +synonym: "down-regulation of transposon integration" EXACT [GOC:mah] +synonym: "downregulation of transposon integration" EXACT [GOC:mah] +synonym: "inhibition of transposon integration" NARROW [GOC:mah] +is_a: GO:0010529 ! negative regulation of transposition +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:0070894 ! regulation of transposon integration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070893 ! transposon integration +relationship: negatively_regulates GO:0070893 ! transposon integration +created_by: mah +creation_date: 2009-09-01T04:20:36Z + +[Term] +id: GO:0070896 +name: positive regulation of transposon integration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule." [GOC:mah] +synonym: "activation of transposon integration" NARROW [GOC:mah] +synonym: "stimulation of transposon integration" NARROW [GOC:mah] +synonym: "up regulation of transposon integration" EXACT [GOC:mah] +synonym: "up-regulation of transposon integration" EXACT [GOC:mah] +synonym: "upregulation of transposon integration" EXACT [GOC:mah] +is_a: GO:0010530 ! positive regulation of transposition +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:0070894 ! regulation of transposon integration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070893 ! transposon integration +relationship: positively_regulates GO:0070893 ! transposon integration +created_by: mah +creation_date: 2009-09-01T04:25:06Z + +[Term] +id: GO:0070897 +name: transcription preinitiation complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription." [GOC:jp, GOC:txnOH] +synonym: "DNA-dependent transcriptional preinitiation complex assembly" EXACT [GOC:txnOH] +synonym: "DNA-templated transcriptional preinitiation complex assembly" EXACT [] +synonym: "transcription PIC biosynthesis" BROAD [GOC:mah] +synonym: "transcription PIC formation" BROAD [GOC:mah] +synonym: "transcriptional preinitiation complex formation" BROAD [GOC:mah] +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0006352 ! DNA-templated transcription, initiation +created_by: mah +creation_date: 2009-09-01T04:33:47Z + +[Term] +id: GO:0070898 +name: RNA polymerase III preinitiation complex assembly +namespace: biological_process +alt_id: GO:0000999 +alt_id: GO:0001020 +alt_id: GO:0001021 +alt_id: GO:0001043 +def: "The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter." [GOC:jp, GOC:txnOH, PMID:11387215, PMID:12381659] +synonym: "RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly" NARROW [] +synonym: "RNA polymerase III transcription PIC biosynthesis" EXACT [GOC:mah] +synonym: "RNA polymerase III transcription PIC formation" EXACT [GOC:mah] +synonym: "RNA polymerase III transcriptional preinitiation complex assembly" EXACT [] +synonym: "RNA polymerase III transcriptional preinitiation complex formation" EXACT [GOC:mah] +synonym: "RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly" NARROW [] +synonym: "RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly" NARROW [] +synonym: "RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly" NARROW [] +is_a: GO:0070897 ! transcription preinitiation complex assembly +relationship: part_of GO:0006384 ! transcription initiation from RNA polymerase III promoter +created_by: mah +creation_date: 2010-08-19T04:16:04Z + +[Term] +id: GO:0070899 +name: mitochondrial tRNA wobble uridine modification +namespace: biological_process +def: "The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified." [GOC:mah, GOC:mcc] +is_a: GO:0002098 ! tRNA wobble uridine modification +is_a: GO:0070900 ! mitochondrial tRNA modification +intersection_of: GO:0002098 ! tRNA wobble uridine modification +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2009-09-02T03:14:13Z + +[Term] +id: GO:0070900 +name: mitochondrial tRNA modification +namespace: biological_process +def: "The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically." [GOC:mah, GOC:mcc] +is_a: GO:0006400 ! tRNA modification +is_a: GO:0070525 ! tRNA threonylcarbamoyladenosine metabolic process +is_a: GO:0090646 ! mitochondrial tRNA processing +is_a: GO:1900864 ! mitochondrial RNA modification +intersection_of: GO:0006400 ! tRNA modification +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2009-09-02T03:16:53Z + +[Term] +id: GO:0070901 +name: mitochondrial tRNA methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule." [GOC:mah, GOC:mcc] +is_a: GO:0030488 ! tRNA methylation +is_a: GO:0070900 ! mitochondrial tRNA modification +intersection_of: GO:0030488 ! tRNA methylation +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2009-09-02T04:08:00Z + +[Term] +id: GO:0070902 +name: mitochondrial tRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule." [GOC:mah, GOC:mcc] +is_a: GO:0031119 ! tRNA pseudouridine synthesis +is_a: GO:0070900 ! mitochondrial tRNA modification +intersection_of: GO:0031119 ! tRNA pseudouridine synthesis +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2009-09-02T04:09:48Z + +[Term] +id: GO:0070903 +name: mitochondrial tRNA thio-modification +namespace: biological_process +def: "The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule." [GOC:mah, GOC:mcc] +is_a: GO:0034227 ! tRNA thio-modification +is_a: GO:0070900 ! mitochondrial tRNA modification +intersection_of: GO:0034227 ! tRNA thio-modification +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2009-09-02T04:11:17Z + +[Term] +id: GO:0070904 +name: transepithelial L-ascorbic acid transport +namespace: biological_process +def: "The directed movement of L-ascorbic acid from one side of an epithelium to the other." [GOC:mah, GOC:yaf] +synonym: "transepithelial L-ascorbate transport" EXACT [GOC:mah] +synonym: "transepithelial vitamin C transport" EXACT [GOC:mah] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0051182 ! coenzyme transport +is_a: GO:0070633 ! transepithelial transport +created_by: mah +creation_date: 2009-09-03T02:21:25Z + +[Term] +id: GO:0070905 +name: serine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 2-amino-3-hydroxypropanoic acid." [GOC:rph] +synonym: "Ser binding" EXACT [GOC:mah] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding +created_by: mah +creation_date: 2009-09-04T03:28:29Z + +[Term] +id: GO:0070906 +name: aspartate:alanine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out)." [GOC:dh] +synonym: "aspartate-alanine antiporter activity" EXACT [GOC:mah] +synonym: "aspartate/alanine antiporter activity" EXACT [GOC:mah] +xref: RHEA:33139 +is_a: GO:0015298 ! solute:cation antiporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +is_a: GO:0022858 ! alanine transmembrane transporter activity +created_by: mah +creation_date: 2009-09-04T03:44:15Z + +[Term] +id: GO:0070907 +name: histidine:histamine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out)." [GOC:dh] +synonym: "histidine-histamine antiporter activity" EXACT [GOC:mah] +synonym: "histidine/histamine antiporter activity" EXACT [GOC:mah] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +created_by: mah +creation_date: 2009-09-04T03:47:07Z + +[Term] +id: GO:0070908 +name: tyrosine:tyramine antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out)." [GOC:dh] +synonym: "tyrosine-tyramine antiporter activity" EXACT [GOC:mah] +synonym: "tyrosine/tyramine antiporter activity" EXACT [GOC:mah] +is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity +is_a: GO:0008504 ! monoamine transmembrane transporter activity +is_a: GO:0015173 ! aromatic amino acid transmembrane transporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +created_by: mah +creation_date: 2009-09-04T03:49:45Z + +[Term] +id: GO:0070909 +name: glutamate:gamma-aminobutyric acid antiporter activity +namespace: molecular_function +def: "Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out)." [GOC:dh] +synonym: "glutamate-gamma-aminobutyric acid antiporter activity" EXACT [GOC:mah] +synonym: "glutamate/gamma-aminobutyric acid antiporter activity" EXACT [GOC:mah] +synonym: "glutamate: GABA antiporter activity" EXACT [GOC:dh] +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +is_a: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity +is_a: GO:0015301 ! anion:anion antiporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +created_by: mah +creation_date: 2009-09-04T03:51:32Z + +[Term] +id: GO:0070910 +name: cell wall macromolecule catabolic process involved in cell wall disassembly +namespace: biological_process +def: "The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall." [GOC:mah] +is_a: GO:0016998 ! cell wall macromolecule catabolic process +intersection_of: GO:0016998 ! cell wall macromolecule catabolic process +intersection_of: part_of GO:0044277 ! cell wall disassembly +relationship: part_of GO:0044277 ! cell wall disassembly +created_by: mah +creation_date: 2009-09-09T02:40:57Z + +[Term] +id: GO:0070911 +name: global genome nucleotide-excision repair +namespace: biological_process +def: "The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome." [PMID:10197977, PMID:18794354] +synonym: "GG-NER" EXACT [PMID:10197977] +synonym: "GGR" EXACT [GOC:vw, PMID:18794354] +synonym: "global genome NER" EXACT [GOC:mah] +synonym: "global genomic nucleotide-excision repair" EXACT [GOC:mah, GOC:vw] +synonym: "global genomic repair" EXACT [GOC:vw, PMID:18794354] +is_a: GO:0006289 ! nucleotide-excision repair +created_by: mah +creation_date: 2009-09-09T03:13:11Z + +[Term] +id: GO:0070912 +name: Ddb1-Ckn1 complex +namespace: cellular_component +def: "A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases." [PMID:18794354] +is_a: GO:0000109 ! nucleotide-excision repair complex +created_by: mah +creation_date: 2009-09-09T03:41:04Z + +[Term] +id: GO:0070913 +name: Ddb1-Wdr21 complex +namespace: cellular_component +def: "A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases." [PMID:18794354] +is_a: GO:0000109 ! nucleotide-excision repair complex +created_by: mah +creation_date: 2009-09-09T03:47:54Z + +[Term] +id: GO:0070914 +name: UV-damage excision repair +namespace: biological_process +def: "A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [GOC:mah, PMID:9619100] +synonym: "AER" RELATED [GOC:mah, PMID:10704216] +synonym: "alternative excision repair" RELATED [GOC:mah, PMID:10704216] +synonym: "UV-damaged DNA endonuclease-dependent excision repair" EXACT [GOC:vw] +synonym: "UVDE-dependent excision repair" EXACT [GOC:vw, PMID:9619100] +synonym: "UVER" EXACT [GOC:vw, PMID:9619100] +is_a: GO:0006281 ! DNA repair +is_a: GO:0034644 ! cellular response to UV +created_by: mah +creation_date: 2009-09-10T03:14:06Z + +[Term] +id: GO:0070915 +name: lysophosphatidic acid receptor activity +namespace: molecular_function +def: "Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein." [GOC:bf, GOC:mah, PMID:15755723] +synonym: "LPA receptor activity" EXACT [PMID:15755723] +is_a: GO:0045125 ! bioactive lipid receptor activity +relationship: has_part GO:0035727 ! lysophosphatidic acid binding +created_by: mah +creation_date: 2009-09-10T05:05:13Z + +[Term] +id: GO:0070916 +name: inositol phosphoceramide synthase complex +namespace: cellular_component +def: "A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces)." [GOC:mah, PMID:19726565] +synonym: "IPC synthase complex" EXACT [GOC:mah] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005794 ! Golgi apparatus +created_by: mah +creation_date: 2009-09-10T05:23:21Z + +[Term] +id: GO:0070917 +name: inositol phosphoceramide synthase regulator activity +namespace: molecular_function +def: "Modulates the activity of inositol phosphoceramide synthase." [GOC:mah] +comment: See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'. +synonym: "IPC synthase regulator activity" EXACT [] +is_a: GO:0030234 ! enzyme regulator activity +relationship: regulates GO:0045140 ! inositol phosphoceramide synthase activity +created_by: mah +creation_date: 2009-09-10T05:27:06Z + +[Term] +id: GO:0070918 +name: production of small RNA involved in gene silencing by RNA +namespace: biological_process +def: "The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease." [GOC:mah, PMID:19239886] +synonym: "gene silencing by RNA, production of guide RNA" EXACT [GOC:mah] +synonym: "gene silencing by RNA, production of small RNA" EXACT [GOC:mah] +is_a: GO:0031050 ! dsRNA processing +relationship: part_of GO:0031047 ! gene silencing by RNA +created_by: mah +creation_date: 2009-09-11T03:32:19Z + +[Term] +id: GO:0070919 +name: production of siRNA involved in chromatin silencing by small RNA +namespace: biological_process +def: "Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA." [GOC:mah, PMID:19239886] +synonym: "chromatin silencing by small RNA, production of guide RNAs" EXACT [] +synonym: "chromatin silencing by small RNA, production of siRNA" EXACT [GOC:mah] +synonym: "production of guide RNAs involved in chromatin silencing by small RNA" EXACT [GOC:mah] +is_a: GO:0070918 ! production of small RNA involved in gene silencing by RNA +relationship: part_of GO:0031048 ! heterochromatin assembly by small RNA +created_by: mah +creation_date: 2009-09-11T03:39:18Z + +[Term] +id: GO:0070920 +name: regulation of production of small RNA involved in gene silencing by RNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA." [GOC:mah] +synonym: "regulation of gene silencing by RNA, production of guide RNA" EXACT [GOC:mah] +synonym: "regulation of gene silencing by RNA, production of small RNA" EXACT [GOC:mah] +is_a: GO:0051252 ! regulation of RNA metabolic process +is_a: GO:0060966 ! regulation of gene silencing by RNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070918 ! production of small RNA involved in gene silencing by RNA +relationship: regulates GO:0070918 ! production of small RNA involved in gene silencing by RNA +created_by: mah +creation_date: 2009-09-11T03:41:59Z + +[Term] +id: GO:0070921 +name: regulation of production of siRNA involved in chromatin silencing by small RNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA." [GOC:mah] +synonym: "regulation of chromatin silencing by small RNA, production of siRNA" EXACT [GOC:mah] +is_a: GO:0070920 ! regulation of production of small RNA involved in gene silencing by RNA +created_by: mah +creation_date: 2009-09-11T03:42:51Z + +[Term] +id: GO:0070922 +name: small RNA loading onto RISC +namespace: biological_process +def: "The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA." [GOC:mah, PMID:19239886] +synonym: "gene silencing by RNA, small RNA loading onto RISC" EXACT [GOC:mah] +synonym: "RISC assembly" RELATED [GOC:mah] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +relationship: part_of GO:0031047 ! gene silencing by RNA +created_by: mah +creation_date: 2009-09-11T03:57:38Z + +[Term] +id: GO:0070923 +name: siRNA loading onto RISC involved in chromatin silencing by small RNA +namespace: biological_process +def: "The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA." [GOC:mah, PMID:19239886] +synonym: "chromatin silencing by small RNA, siRNA loading onto RISC" EXACT [GOC:mah] +is_a: GO:0070922 ! small RNA loading onto RISC +relationship: part_of GO:0031048 ! heterochromatin assembly by small RNA +created_by: mah +creation_date: 2009-09-11T04:01:44Z + +[Term] +id: GO:0070925 +name: organelle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] +subset: goslim_yeast +is_a: GO:0006996 ! organelle organization +is_a: GO:0022607 ! cellular component assembly +created_by: mah +creation_date: 2009-09-15T03:00:51Z + +[Term] +id: GO:0070926 +name: regulation of ATP:ADP antiporter activity +namespace: biological_process +def: "Any process that modulates the activity of an ATP:ADP antiporter." [GOC:BHF, GOC:mah] +is_a: GO:0032239 ! regulation of nucleobase-containing compound transport +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1903959 ! regulation of anion transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005471 ! ATP:ADP antiporter activity +relationship: regulates GO:0005471 ! ATP:ADP antiporter activity +created_by: mah +creation_date: 2009-09-16T02:56:35Z + +[Term] +id: GO:0070927 +name: negative regulation of ATP:ADP antiporter activity +namespace: biological_process +def: "Any process that stops or reduces the activity of an ATP:ADP antiporter." [GOC:BHF, GOC:mah] +synonym: "down regulation of ATP:ADP antiporter activity" EXACT [GOC:mah] +synonym: "down-regulation of ATP:ADP antiporter activity" EXACT [GOC:mah] +synonym: "downregulation of ATP:ADP antiporter activity" EXACT [GOC:mah] +synonym: "inhibition of ATP:ADP antiporter activity" NARROW [GOC:mah] +is_a: GO:0032240 ! negative regulation of nucleobase-containing compound transport +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0070926 ! regulation of ATP:ADP antiporter activity +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005471 ! ATP:ADP antiporter activity +relationship: negatively_regulates GO:0005471 ! ATP:ADP antiporter activity +created_by: mah +creation_date: 2009-09-16T02:58:02Z + +[Term] +id: GO:0070928 +name: regulation of mRNA stability, ncRNA-mediated +namespace: biological_process +def: "Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs." [GOC:jh2] +synonym: "ncRNA-mediated regulation of mRNA stability" EXACT [GOC:mah] +synonym: "regulation of mRNA stability, non-coding RNA-mediated" EXACT [GOC:mah] +is_a: GO:0043488 ! regulation of mRNA stability +created_by: mah +creation_date: 2009-09-16T03:26:21Z + +[Term] +id: GO:0070929 +name: trans-translation +namespace: biological_process +def: "A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes." [GOC:jh2, GOC:mah] +is_a: GO:0006414 ! translational elongation +created_by: mah +creation_date: 2009-09-16T04:06:12Z + +[Term] +id: GO:0070930 +name: trans-translation-dependent protein tagging +namespace: biological_process +def: "A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation." [GOC:jh2, GOC:jsg, GOC:mah] +comment: Note that this term is not a child of 'co-translational protein modification process ; GO:0043686' because co-translational protein modification implies modification of a previously incorporated amino acid in a nascent chain, rather than addition of new sequence to the C-terminus. +synonym: "co-translational protein tagging" EXACT [GOC:jh2, GOC:jsg] +synonym: "cotranslational protein tagging" EXACT [GOC:mah] +synonym: "protein modification by trans-translation" EXACT [GOC:mah] +is_a: GO:0006464 ! cellular protein modification process +relationship: has_part GO:0070929 ! trans-translation +created_by: mah +creation_date: 2009-09-16T04:10:49Z + +[Term] +id: GO:0070931 +name: Golgi-associated vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a Golgi-associated vesicle." [GOC:mah] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0005798 ! Golgi-associated vesicle +created_by: mah +creation_date: 2009-09-16T04:26:50Z + +[Term] +id: GO:0070932 +name: histone H3 deacetylation +namespace: biological_process +def: "The modification of histone H3 by the removal of one or more acetyl groups." [GOC:BHF, GOC:rl] +is_a: GO:0016575 ! histone deacetylation +created_by: mah +creation_date: 2009-09-16T04:50:55Z + +[Term] +id: GO:0070933 +name: histone H4 deacetylation +namespace: biological_process +def: "The modification of histone H4 by the removal of one or more acetyl groups." [GOC:BHF, GOC:rl] +is_a: GO:0016575 ! histone deacetylation +created_by: mah +creation_date: 2009-09-16T04:53:06Z + +[Term] +id: GO:0070934 +name: CRD-mediated mRNA stabilization +namespace: biological_process +def: "An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD)." [GOC:mah, PMID:19029303] +synonym: "coding region determinant-mediated mRNA stabilization" EXACT [GOC:mah] +is_a: GO:0048255 ! mRNA stabilization +created_by: mah +creation_date: 2009-09-21T02:57:06Z + +[Term] +id: GO:0070935 +name: 3'-UTR-mediated mRNA stabilization +namespace: biological_process +def: "An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA." [GOC:mah, PMID:19029303] +synonym: "3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:mah] +is_a: GO:0048255 ! mRNA stabilization +created_by: mah +creation_date: 2009-09-21T03:08:20Z + +[Term] +id: GO:0070936 +name: protein K48-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation." [GOC:cvs, PMID:15556404] +synonym: "protein K48-linked polyubiquitination" EXACT [GOC:mah] +is_a: GO:0000209 ! protein polyubiquitination +created_by: mah +creation_date: 2009-09-21T03:25:27Z + +[Term] +id: GO:0070937 +name: CRD-mediated mRNA stability complex +namespace: cellular_component +def: "A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9." [GOC:mah, PMID:19029303] +comment: See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'. +synonym: "coding-region determinant of instability-mediated mRNA stability complex" EXACT [] +synonym: "coding-region instability determinant -mediated mRNA stability complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-09-22T02:00:22Z + +[Term] +id: GO:0070938 +name: contractile ring +namespace: cellular_component +def: "A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles." [GOC:mah, ISBN:0123645859, ISBN:0792354923, PMID:10791428, PMID:17913889] +synonym: "constriction ring" RELATED [GOC:mah] +synonym: "cytokinetic ring" RELATED [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +created_by: mah +creation_date: 2009-09-22T02:41:32Z + +[Term] +id: GO:0070939 +name: Dsl1/NZR complex +namespace: cellular_component +def: "A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p." [GOC:jh, GOC:mah, PMID:19151722, PMID:21550981] +comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'. +synonym: "CATCHR family complex" BROAD [] +synonym: "Dsl1p complex" EXACT [PMID:19151722] +synonym: "NZR complex" EXACT [PMID:25364732] +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +created_by: mah +creation_date: 2009-09-22T03:41:38Z + +[Term] +id: GO:0070940 +name: dephosphorylation of RNA polymerase II C-terminal domain +namespace: biological_process +def: "The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form." [GOC:krc, GOC:mah, PMID:17079683] +synonym: "CTD domain dephosphorylation of RNA polymerase II" EXACT [GOC:mah] +synonym: "generation of hypophosphorylated CTD of RNA polymerase II" EXACT [GOC:krc] +synonym: "generation of II(A) form of RNA polymerase II" EXACT [GOC:krc] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0006470 ! protein dephosphorylation +created_by: mah +creation_date: 2009-09-29T04:34:14Z + +[Term] +id: GO:0070941 +name: eisosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane." [GOC:al, GOC:jp, GOC:mah, PMID:19564405] +is_a: GO:0022607 ! cellular component assembly +created_by: mah +creation_date: 2009-09-30T02:49:30Z + +[Term] +id: GO:0070942 +name: neutrophil mediated cytotoxicity +namespace: biological_process +def: "The directed killing of a target cell by a neutrophil." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated cell killing" EXACT [GOC:add] +is_a: GO:0001909 ! leukocyte mediated cytotoxicity +is_a: GO:0002446 ! neutrophil mediated immunity +created_by: mah +creation_date: 2009-10-01T01:49:30Z + +[Term] +id: GO:0070943 +name: neutrophil-mediated killing of symbiont cell +namespace: biological_process +def: "The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated killing of symbiont cell" EXACT [] +is_a: GO:0051873 ! killing by host of symbiont cells +is_a: GO:0070942 ! neutrophil mediated cytotoxicity +created_by: mah +creation_date: 2009-10-01T01:52:03Z + +[Term] +id: GO:0070944 +name: neutrophil-mediated killing of bacterium +namespace: biological_process +def: "The directed killing of a bacterium by a neutrophil." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated killing of bacterium" EXACT [] +is_a: GO:0070943 ! neutrophil-mediated killing of symbiont cell +relationship: part_of GO:0042742 ! defense response to bacterium +created_by: mah +creation_date: 2009-10-01T01:55:56Z + +[Term] +id: GO:0070945 +name: neutrophil-mediated killing of gram-negative bacterium +namespace: biological_process +def: "The directed killing of a gram-negative bacterium by a neutrophil." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated killing of gram-negative bacterium" EXACT [] +is_a: GO:0070944 ! neutrophil-mediated killing of bacterium +relationship: part_of GO:0050829 ! defense response to Gram-negative bacterium +created_by: mah +creation_date: 2009-10-01T01:59:12Z + +[Term] +id: GO:0070946 +name: neutrophil-mediated killing of gram-positive bacterium +namespace: biological_process +def: "The directed killing of a gram-positive bacterium by a neutrophil." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated killing of gram-positive bacterium" EXACT [] +is_a: GO:0070944 ! neutrophil-mediated killing of bacterium +relationship: part_of GO:0050830 ! defense response to Gram-positive bacterium +created_by: mah +creation_date: 2009-10-01T02:04:15Z + +[Term] +id: GO:0070947 +name: neutrophil-mediated killing of fungus +namespace: biological_process +def: "The directed killing of a fungal cell by a neutrophil." [GOC:add, ISBN:0781765196] +synonym: "neutrophil mediated killing of fungus" EXACT [] +is_a: GO:0070943 ! neutrophil-mediated killing of symbiont cell +relationship: part_of GO:0050832 ! defense response to fungus +created_by: mah +creation_date: 2009-10-01T02:07:44Z + +[Term] +id: GO:0070948 +name: regulation of neutrophil mediated cytotoxicity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "regulation of neutrophil mediated cell killing" EXACT [GOC:add] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070942 ! neutrophil mediated cytotoxicity +relationship: regulates GO:0070942 ! neutrophil mediated cytotoxicity +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070949 +name: regulation of neutrophil mediated killing of symbiont cell +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil." [GOC:add, GOC:mah] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0051709 ! regulation of killing of cells of other organism +is_a: GO:0070948 ! regulation of neutrophil mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +relationship: regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070950 +name: regulation of neutrophil mediated killing of bacterium +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil." [GOC:add, GOC:mah] +is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070944 ! neutrophil-mediated killing of bacterium +relationship: regulates GO:0070944 ! neutrophil-mediated killing of bacterium +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070951 +name: regulation of neutrophil mediated killing of gram-negative bacterium +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil." [GOC:add, GOC:mah] +is_a: GO:0070950 ! regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +relationship: regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070952 +name: regulation of neutrophil mediated killing of gram-positive bacterium +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil." [GOC:add, GOC:mah] +is_a: GO:0070950 ! regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +relationship: regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070953 +name: regulation of neutrophil mediated killing of fungus +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil." [GOC:add, GOC:mah] +is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell +is_a: GO:1900150 ! regulation of defense response to fungus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070947 ! neutrophil-mediated killing of fungus +relationship: regulates GO:0070947 ! neutrophil-mediated killing of fungus +created_by: mah +creation_date: 2009-10-01T02:14:36Z + +[Term] +id: GO:0070954 +name: negative regulation of neutrophil mediated cytotoxicity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated cytotoxicity" NARROW [GOC:mah] +synonym: "negative regulation of neutrophil mediated cell killing" EXACT [GOC:add] +is_a: GO:0001911 ! negative regulation of leukocyte mediated cytotoxicity +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0070948 ! regulation of neutrophil mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070942 ! neutrophil mediated cytotoxicity +relationship: negatively_regulates GO:0070942 ! neutrophil mediated cytotoxicity +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070955 +name: negative regulation of neutrophil mediated killing of symbiont cell +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated killing of symbiont cell" NARROW [GOC:mah] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0051711 ! negative regulation of killing of cells of other organism +is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell +is_a: GO:0070954 ! negative regulation of neutrophil mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +relationship: negatively_regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070956 +name: negative regulation of neutrophil mediated killing of bacterium +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated killing of bacterium" NARROW [GOC:mah] +is_a: GO:0070950 ! regulation of neutrophil mediated killing of bacterium +is_a: GO:0070955 ! negative regulation of neutrophil mediated killing of symbiont cell +is_a: GO:1900425 ! negative regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070944 ! neutrophil-mediated killing of bacterium +relationship: negatively_regulates GO:0070944 ! neutrophil-mediated killing of bacterium +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070957 +name: negative regulation of neutrophil mediated killing of gram-negative bacterium +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated killing of gram-negative bacterium" NARROW [GOC:mah] +is_a: GO:0070951 ! regulation of neutrophil mediated killing of gram-negative bacterium +is_a: GO:0070956 ! negative regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +relationship: negatively_regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070958 +name: negative regulation of neutrophil mediated killing of gram-positive bacterium +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated killing of gram-positive bacterium" NARROW [GOC:mah] +is_a: GO:0070952 ! regulation of neutrophil mediated killing of gram-positive bacterium +is_a: GO:0070956 ! negative regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +relationship: negatively_regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070959 +name: negative regulation of neutrophil mediated killing of fungus +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "down regulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +synonym: "down-regulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +synonym: "downregulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +synonym: "inhibition of neutrophil mediated killing of fungus" NARROW [GOC:mah] +is_a: GO:0070953 ! regulation of neutrophil mediated killing of fungus +is_a: GO:0070955 ! negative regulation of neutrophil mediated killing of symbiont cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070947 ! neutrophil-mediated killing of fungus +relationship: negatively_regulates GO:0070947 ! neutrophil-mediated killing of fungus +created_by: mah +creation_date: 2009-10-01T02:20:17Z + +[Term] +id: GO:0070960 +name: positive regulation of neutrophil mediated cytotoxicity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated cytotoxicity" NARROW [GOC:mah] +synonym: "positive regulation of neutrophil mediated cell killing" EXACT [GOC:add] +synonym: "stimulation of neutrophil mediated cytotoxicity" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated cytotoxicity" EXACT [GOC:mah] +is_a: GO:0001912 ! positive regulation of leukocyte mediated cytotoxicity +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0070948 ! regulation of neutrophil mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070942 ! neutrophil mediated cytotoxicity +relationship: positively_regulates GO:0070942 ! neutrophil mediated cytotoxicity +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070961 +name: positive regulation of neutrophil mediated killing of symbiont cell +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated killing of symbiont cell" NARROW [GOC:mah] +synonym: "stimulation of neutrophil mediated killing of symbiont cell" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated killing of symbiont cell" EXACT [GOC:mah] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0051712 ! positive regulation of killing of cells of other organism +is_a: GO:0070949 ! regulation of neutrophil mediated killing of symbiont cell +is_a: GO:0070960 ! positive regulation of neutrophil mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +relationship: positively_regulates GO:0070943 ! neutrophil-mediated killing of symbiont cell +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070962 +name: positive regulation of neutrophil mediated killing of bacterium +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated killing of bacterium" NARROW [GOC:mah] +synonym: "stimulation of neutrophil mediated killing of bacterium" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated killing of bacterium" EXACT [GOC:mah] +is_a: GO:0070950 ! regulation of neutrophil mediated killing of bacterium +is_a: GO:0070961 ! positive regulation of neutrophil mediated killing of symbiont cell +is_a: GO:1900426 ! positive regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070944 ! neutrophil-mediated killing of bacterium +relationship: positively_regulates GO:0070944 ! neutrophil-mediated killing of bacterium +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070963 +name: positive regulation of neutrophil mediated killing of gram-negative bacterium +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated killing of gram-negative bacterium" NARROW [GOC:mah] +synonym: "stimulation of neutrophil mediated killing of gram-negative bacterium" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated killing of gram-negative bacterium" EXACT [GOC:mah] +is_a: GO:0070951 ! regulation of neutrophil mediated killing of gram-negative bacterium +is_a: GO:0070962 ! positive regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +relationship: positively_regulates GO:0070945 ! neutrophil-mediated killing of gram-negative bacterium +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070964 +name: positive regulation of neutrophil mediated killing of gram-positive bacterium +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated killing of gram-positive bacterium" NARROW [GOC:mah] +synonym: "stimulation of neutrophil mediated killing of gram-positive bacterium" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated killing of gram-positive bacterium" EXACT [GOC:mah] +is_a: GO:0070952 ! regulation of neutrophil mediated killing of gram-positive bacterium +is_a: GO:0070962 ! positive regulation of neutrophil mediated killing of bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +relationship: positively_regulates GO:0070946 ! neutrophil-mediated killing of gram-positive bacterium +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070965 +name: positive regulation of neutrophil mediated killing of fungus +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil." [GOC:add, GOC:mah] +synonym: "activation of neutrophil mediated killing of fungus" NARROW [GOC:mah] +synonym: "stimulation of neutrophil mediated killing of fungus" NARROW [GOC:mah] +synonym: "up regulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +synonym: "up-regulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +synonym: "upregulation of neutrophil mediated killing of fungus" EXACT [GOC:mah] +is_a: GO:0070953 ! regulation of neutrophil mediated killing of fungus +is_a: GO:0070961 ! positive regulation of neutrophil mediated killing of symbiont cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070947 ! neutrophil-mediated killing of fungus +relationship: positively_regulates GO:0070947 ! neutrophil-mediated killing of fungus +created_by: mah +creation_date: 2009-10-01T02:28:49Z + +[Term] +id: GO:0070966 +name: nuclear-transcribed mRNA catabolic process, no-go decay +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation." [GOC:jp, PMID:16554824] +synonym: "no-go decay" EXACT [GOC:jp] +synonym: "no-go mRNA decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA breakdown, no-go decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA catabolism, no-go decay" EXACT [GOC:jp] +synonym: "nuclear-transcribed mRNA degradation, no-go decay" EXACT [GOC:jp] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process +created_by: mah +creation_date: 2009-10-01T02:36:22Z + +[Term] +id: GO:0070967 +name: coenzyme F420 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:dh] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0097367 ! carbohydrate derivative binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mah +creation_date: 2009-10-02T11:33:26Z + +[Term] +id: GO:0070968 +name: pyrroloquinoline quinone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases." [GOC:dh] +synonym: "PQQ binding" EXACT [GOC:dh] +is_a: GO:0019842 ! vitamin binding +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0048038 ! quinone binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mah +creation_date: 2009-10-02T11:39:13Z + +[Term] +id: GO:0070970 +name: interleukin-2 secretion +namespace: biological_process +def: "The regulated release of interleukin-2 from a cell." [GOC:mah, PMID:16930574] +synonym: "IL-2 secretion" EXACT [GOC:mah] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032623 ! interleukin-2 production +created_by: mah +creation_date: 2009-10-02T12:03:07Z + +[Term] +id: GO:0070971 +name: endoplasmic reticulum exit site +namespace: cellular_component +def: "An endoplasmic reticulum part at which COPII-coated vesicles are produced." [NIF_Subcellular:sao124393998, PMID:15623529, PMID:16957052] +synonym: "ER exit site" EXACT [GOC:mah] +synonym: "transitional ER" EXACT [PMID:15623529] +xref: NIF_Subcellular:sao124393998 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005783 ! endoplasmic reticulum +created_by: mah +creation_date: 2009-10-02T12:19:23Z + +[Term] +id: GO:0070972 +name: protein localization to endoplasmic reticulum +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum." [GOC:mah] +synonym: "protein localisation in endoplasmic reticulum" EXACT [GOC:mah] +synonym: "protein localization in endoplasmic reticulum" EXACT [] +synonym: "protein localization in ER" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2009-10-02T12:43:34Z + +[Term] +id: GO:0070973 +name: protein localization to endoplasmic reticulum exit site +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site." [GOC:mah] +synonym: "protein localisation to endoplasmic reticulum exit site" EXACT [GOC:mah] +synonym: "protein localization to ER exit site" EXACT [GOC:mah] +is_a: GO:0070972 ! protein localization to endoplasmic reticulum +created_by: mah +creation_date: 2009-10-02T12:45:41Z + +[Term] +id: GO:0070974 +name: POU domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors." [GOC:mah, GOC:yaf, InterPro:IPR000327] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2009-10-02T12:53:02Z + +[Term] +id: GO:0070975 +name: FHA domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich." [GOC:mah, InterPro:IPR000253] +synonym: "Forkhead-associated domain binding" EXACT [InterPro:IPR000253] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2009-10-02T01:09:20Z + +[Term] +id: GO:0070976 +name: TIR domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components." [GOC:mah, InterPro:IPR000157] +subset: goslim_chembl +synonym: "Toll-Interleukin receptor domain binding" EXACT [InterPro:IPR000157] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2009-10-02T01:17:29Z + +[Term] +id: GO:0070977 +name: bone maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah] +is_a: GO:0048799 ! animal organ maturation +relationship: part_of GO:0060348 ! bone development +created_by: mah +creation_date: 2009-10-05T04:35:31Z + +[Term] +id: GO:0070978 +name: voltage-gated calcium channel complex assembly +namespace: biological_process +def: "Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex." [GOC:mh] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: mah +creation_date: 2009-10-06T04:51:13Z + +[Term] +id: GO:0070979 +name: protein K11-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains." [GOC:jsg, GOC:pr, GOC:sp, PMID:18485873, PMID:20655260, PMID:21113135] +is_a: GO:0000209 ! protein polyubiquitination +created_by: mah +creation_date: 2009-10-26T04:50:57Z + +[Term] +id: GO:0070980 +name: biphenyl catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)." [PMID:16310831, PMID:16339959, UniPathway:UPA00155] +synonym: "biphenyl breakdown" EXACT [GOC:mah] +synonym: "biphenyl catabolism" EXACT [GOC:mah] +synonym: "biphenyl degradation" EXACT [GOC:mah] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0018879 ! biphenyl metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: mah +creation_date: 2009-10-27T11:24:59Z + +[Term] +id: GO:0070981 +name: L-asparagine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid." [GOC:mah] +synonym: "L-asparagine anabolism" EXACT [GOC:mah] +synonym: "L-asparagine biosynthesis" EXACT [GOC:mah] +synonym: "L-asparagine formation" EXACT [GOC:mah] +synonym: "L-asparagine synthesis" EXACT [GOC:mah] +is_a: GO:0006529 ! asparagine biosynthetic process +is_a: GO:0070982 ! L-asparagine metabolic process +created_by: mah +creation_date: 2009-10-27T12:59:42Z + +[Term] +id: GO:0070982 +name: L-asparagine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid." [GOC:mah] +synonym: "L-asparagine metabolism" EXACT [GOC:mah] +is_a: GO:0006528 ! asparagine metabolic process +is_a: GO:0017144 ! drug metabolic process +created_by: mah +creation_date: 2009-10-27T01:03:46Z + +[Term] +id: GO:0070983 +name: dendrite guidance +namespace: biological_process +def: "The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues." [GOC:sart, PMID:15046878] +synonym: "dendritic guidance" EXACT [GOC:sart] +is_a: GO:0097485 ! neuron projection guidance +relationship: part_of GO:0048813 ! dendrite morphogenesis +created_by: mah +creation_date: 2009-10-27T03:53:23Z + +[Term] +id: GO:0070984 +name: SET domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation." [GOC:sart, Pfam:PF00856, PMID:12575990] +synonym: "SET binding" EXACT [GOC:sart] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2009-10-27T04:09:28Z + +[Term] +id: GO:0070985 +name: transcription factor TFIIK complex +namespace: cellular_component +def: "A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7." [GOC:mah, PMID:19818408, PMID:22572993] +synonym: "cyclin H-CDK7 complex" RELATED [] +synonym: "Mcs6/Mcs2/Pmh1 complex" NARROW [GOC:vw, PMID:19328067] +synonym: "TFIIK complex" EXACT [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005675 ! transcription factor TFIIH holo complex +created_by: mah +creation_date: 2009-10-27T04:19:37Z + +[Term] +id: GO:0070986 +name: left/right axis specification +namespace: biological_process +def: "The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes)." [GOC:dph, GOC:gvg, GOC:mah] +synonym: "left-right axis specification" EXACT [GOC:mah] +synonym: "left/right axis determination" RELATED [GOC:dph] +is_a: GO:0009798 ! axis specification +relationship: part_of GO:0060972 ! left/right pattern formation +created_by: mah +creation_date: 2009-10-29T01:43:34Z + +[Term] +id: GO:0070987 +name: error-free translesion synthesis +namespace: biological_process +def: "The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level." [GOC:elh] +comment: Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication. +is_a: GO:0019985 ! translesion synthesis +created_by: mah +creation_date: 2009-10-29T02:45:42Z + +[Term] +id: GO:0070988 +name: demethylation +namespace: biological_process +def: "The process of removing one or more methyl groups from a molecule." [GOC:BHF, GOC:rl] +is_a: GO:0008152 ! metabolic process +created_by: mah +creation_date: 2009-10-29T03:12:51Z + +[Term] +id: GO:0070989 +name: oxidative demethylation +namespace: biological_process +def: "The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate." [GOC:BHF, GOC:mah, GOC:rl] +subset: goslim_chembl +is_a: GO:0055114 ! oxidation-reduction process +is_a: GO:0070988 ! demethylation +created_by: mah +creation_date: 2009-10-29T03:33:25Z + +[Term] +id: GO:0070990 +name: snRNP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a small nuclear ribonucleoprotein particle." [GOC:BHF, GOC:mah, GOC:rl] +is_a: GO:0043021 ! ribonucleoprotein complex binding +created_by: mah +creation_date: 2009-10-29T03:54:25Z + +[Term] +id: GO:0070991 +name: medium-chain-acyl-CoA dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12." [GOC:BHF, GOC:mah] +synonym: "MCAD activity" EXACT [GOC:mah] +xref: EC:1.3.99 +is_a: GO:0003995 ! acyl-CoA dehydrogenase activity +created_by: mah +creation_date: 2009-10-29T04:11:49Z + +[Term] +id: GO:0070992 +name: translation initiation complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site." [GOC:hjd, GOC:mah] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-10-30T01:23:52Z + +[Term] +id: GO:0070993 +name: translation preinitiation complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA." [GOC:hjd, GOC:mah] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-10-30T01:25:00Z + +[Term] +id: GO:0070994 +name: detection of oxidative stress +namespace: biological_process +def: "The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal." [GOC:mah] +is_a: GO:0006979 ! response to oxidative stress +created_by: mah +creation_date: 2009-10-30T02:54:35Z + +[Term] +id: GO:0070995 +name: NADPH oxidation +namespace: biological_process +def: "A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP." [GOC:BHF, GOC:mah] +synonym: "NADP (reduced) dehydrogenation" EXACT [GOC:mah] +synonym: "NADP (reduced) oxidation" EXACT [GOC:mah] +synonym: "NADPH dehydrogenation" EXACT [GOC:mah] +synonym: "reduced NADP dehydrogenation" EXACT [GOC:mah] +synonym: "reduced NADP oxidation" EXACT [GOC:mah] +synonym: "reduced nicotinamide adenine dinucleotide phosphate dehydrogenation" EXACT [GOC:mah] +synonym: "reduced nicotinamide adenine dinucleotide phosphate oxidation" EXACT [GOC:mah] +is_a: GO:0006739 ! NADP metabolic process +is_a: GO:0055114 ! oxidation-reduction process +created_by: mah +creation_date: 2009-11-03T12:02:15Z + +[Term] +id: GO:0070996 +name: type 1 melanocortin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type 1 melanocortin receptor." [GOC:BHF, GOC:mah] +synonym: "type 1 melanocortin receptor ligand" NARROW [GOC:mah] +is_a: GO:0031779 ! melanocortin receptor binding +created_by: mah +creation_date: 2009-11-03T01:50:53Z + +[Term] +id: GO:0070997 +name: neuron death +namespace: biological_process +def: "The process of cell death in a neuron." [GOC:BHF, GOC:mah] +comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate. +synonym: "neuron cell death" EXACT [GOC:mah, GOC:rl] +synonym: "neuronal cell death" EXACT [GOC:mah] +is_a: GO:0008219 ! cell death +created_by: mah +creation_date: 2009-11-03T02:37:17Z + +[Term] +id: GO:0070998 +name: sensory perception of gravity +namespace: biological_process +def: "The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:mah] +is_a: GO:0007600 ! sensory perception +created_by: mah +creation_date: 2009-11-03T03:25:12Z + +[Term] +id: GO:0070999 +name: detection of mechanical stimulus involved in sensory perception of gravity +namespace: biological_process +def: "The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah] +is_a: GO:0009590 ! detection of gravity +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0070998 ! sensory perception of gravity +relationship: part_of GO:0070998 ! sensory perception of gravity +created_by: mah +creation_date: 2009-11-03T03:27:30Z + +[Term] +id: GO:0071000 +name: response to magnetism +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus." [GOC:sl] +synonym: "response to magnetic stimulus" EXACT [GOC:mah] +is_a: GO:0009628 ! response to abiotic stimulus +created_by: mah +creation_date: 2009-11-04T12:02:03Z + +[Term] +id: GO:0071001 +name: U4/U6 snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains base-paired U4 and U6 small nuclear RNAs." [GOC:mah, PMID:14685174] +is_a: GO:0097525 ! spliceosomal snRNP complex +relationship: has_part GO:0005687 ! U4 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071002 +name: U4atac/U6atac snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains base-paired U4atac and U6atac small nuclear RNAs." [GOC:mah, PMID:14685174] +is_a: GO:0097525 ! spliceosomal snRNP complex +relationship: has_part GO:0005690 ! U4atac snRNP +relationship: has_part GO:0005691 ! U6atac snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071003 +name: penta-snRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins." [GOC:mah, PMID:11804584, PMID:12724403] +synonym: "penta-RNP complex" EXACT [GOC:rb] +is_a: GO:0097525 ! spliceosomal snRNP complex +relationship: has_part GO:0005682 ! U5 snRNP +relationship: has_part GO:0005685 ! U1 snRNP +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0071001 ! U4/U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071004 +name: U2-type prespliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation." [GOC:ab, GOC:krc, GOC:mah, PMID:17332742, PMID:19239890] +synonym: "GT-AG prespliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "major prespliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex A" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "yeast U2-type spliceosomal complex B" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071010 ! prespliceosome +relationship: has_part GO:0005685 ! U1 snRNP +relationship: has_part GO:0005686 ! U2 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071005 +name: U2-type precatalytic spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890] +synonym: "GT-AG precatalytic spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "major precatalytic spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex B" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U2-type spliceosomal complex B1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast U12-type spliceosomal complex A2-1" RELATED [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071011 ! precatalytic spliceosome +relationship: has_part GO:0005685 ! U1 snRNP +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0046540 ! U4/U6 x U5 tri-snRNP complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071006 +name: U2-type catalytic step 1 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:18322460, PMID:19239890] +synonym: "GT-AG catalytic step 1 spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "major catalytic step 1 spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex B*" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U2-type spliceosomal complex B2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "U2-type activated spliceosome" EXACT [GOC:krc, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast U2-type spliceosomal complex A1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071012 ! catalytic step 1 spliceosome +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071007 +name: U2-type catalytic step 2 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:18322460, PMID:19239890] +synonym: "GT-AG catalytic step 2 spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "major catalytic step 2 spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex C" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U2-type spliceosomal complex C1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast U2-type spliceosomal complex A2-2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071013 ! catalytic step 2 spliceosome +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071008 +name: U2-type post-mRNA release spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "GT-AG post-mRNA release spliceosomal complex" NARROW [GOC:krc, GOC:mah] +synonym: "major post-mRNA release spliceosomal complex" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex I" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "U2/U5/U6 snRNP complex" EXACT [GOC:mah, PMID:12374752, PMID:20400941, PMID:24442611] +synonym: "U2/U5/U6 tri-snRNP complex" EXACT [GOC:mah, PMID:12374752, PMID:20400941] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071014 ! post-mRNA release spliceosomal complex +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071009 +name: U4atac/U6atac x U5 tri-snRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex formed by the association of the U4atac/U6atac and U5 small nuclear ribonucleoproteins." [GOC:krc, GOC:mah, GOC:pr, PMID:16201866] +synonym: "U4atac/U6atac.U5 snRNP complex" EXACT [] +is_a: GO:0097526 ! spliceosomal tri-snRNP complex +relationship: has_part GO:0005682 ! U5 snRNP +relationship: has_part GO:0071002 ! U4atac/U6atac snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071010 +name: prespliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex." [GOC:ab, GOC:krc, GOC:mah, PMID:17332742, PMID:19239890] +synonym: "mammalian spliceosomal complex A" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "prespliceosomal complex" EXACT [GOC:vw] +synonym: "yeast spliceosomal complex B" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071011 +name: precatalytic spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890] +synonym: "mammalian spliceosomal complex B" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian spliceosomal complex B1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast spliceosomal complex A2-1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071012 +name: catalytic step 1 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890] +synonym: "activated spliceosome" EXACT [GOC:krc, ISBN:0879695897, ISBN:0879697393] +synonym: "mammalian spliceosomal complex B*" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian spliceosomal complex B2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast spliceosomal complex A1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +is_a: GO:1902494 ! catalytic complex +relationship: has_part GO:0000974 ! Prp19 complex +relationship: has_part GO:0005682 ! U5 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071013 +name: catalytic step 2 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:18322460, PMID:19239890] +synonym: "mammalian spliceosomal complex C" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian spliceosomal complex C1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast spliceosomal complex A2-2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +is_a: GO:1902494 ! catalytic complex +relationship: has_part GO:0000974 ! Prp19 complex +relationship: has_part GO:0005682 ! U5 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071014 +name: post-mRNA release spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian spliceosomal complex I" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +relationship: has_part GO:0005682 ! U5 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071015 +name: U12-type prespliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation." [GOC:ab, GOC:krc, GOC:mah, PMID:10197985, PMID:16201866] +synonym: "AT-AC prespliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex A" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "minor prespliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "yeast U12-type spliceosomal complex B" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0071010 ! prespliceosome +relationship: has_part GO:0034693 ! U11/U12 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071016 +name: U12-type precatalytic spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs." [GOC:ab, GOC:krc, GOC:mah, PMID:16201866] +synonym: "AT-AC precatalytic spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex B" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U12-type spliceosomal complex B1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "minor precatalytic spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "yeast U12-type spliceosomal complex A2-1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0071011 ! precatalytic spliceosome +relationship: has_part GO:0005692 ! U11 snRNP +relationship: has_part GO:0005693 ! U12 snRNP +relationship: has_part GO:0071009 ! U4atac/U6atac x U5 tri-snRNP complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071017 +name: U12-type catalytic step 1 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:16201866] +synonym: "AT-AC catalytic step 1 spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex B*" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U12-type spliceosomal complex B2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "minor catalytic step 1 spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "U12-type activated spliceosome" EXACT [GOC:krc, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast U12-type spliceosomal complex A1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0071012 ! catalytic step 1 spliceosome +relationship: has_part GO:0005691 ! U6atac snRNP +relationship: has_part GO:0005693 ! U12 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071018 +name: U12-type catalytic step 2 spliceosome +namespace: cellular_component +def: "A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:16201866] +synonym: "AT-AC catalytic step 2 spliceosome" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex C" NARROW [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:19239890] +synonym: "mammalian U12-type spliceosomal complex C1" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "minor catalytic step 2 spliceosome" EXACT [GOC:krc, GOC:mah] +synonym: "yeast U12-type spliceosomal complex A2-2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0071013 ! catalytic step 2 spliceosome +relationship: has_part GO:0005691 ! U6atac snRNP +relationship: has_part GO:0005693 ! U12 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071019 +name: U12-type post-mRNA release spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:16201866] +synonym: "AT-AC post-mRNA release spliceosomal complex" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex I" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "minor post-mRNA release spliceosomal complex" EXACT [GOC:krc, GOC:mah] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0005691 ! U6atac snRNP +is_a: GO:0005693 ! U12 snRNP +is_a: GO:0071014 ! post-mRNA release spliceosomal complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071020 +name: post-spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5." [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "mammalian spliceosomal complex C2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast spliceosomal complex A2-3" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +relationship: has_part GO:0005682 ! U5 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071021 +name: U2-type post-spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6." [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "GT-AG post-spliceosomal complex" NARROW [GOC:krc, GOC:mah] +synonym: "major post-spliceosomal complex" EXACT [GOC:krc, GOC:mah] +synonym: "mammalian U2-type spliceosomal complex C2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "yeast U2-type spliceosomal complex A2-3" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005684 ! U2-type spliceosomal complex +is_a: GO:0071020 ! post-spliceosomal complex +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071022 +name: U12-type post-spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac." [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "AT-AC post-spliceosomal complex" NARROW [GOC:krc, GOC:mah] +synonym: "mammalian U12-type spliceosomal complex C2" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +synonym: "minor post-spliceosomal complex" EXACT [GOC:krc, GOC:mah] +synonym: "yeast U12-type spliceosomal complex A2-3" NARROW [GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393] +is_a: GO:0005689 ! U12-type spliceosomal complex +is_a: GO:0071020 ! post-spliceosomal complex +relationship: has_part GO:0005691 ! U6atac snRNP +relationship: has_part GO:0005693 ! U12 snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071023 +name: trans spliceosomal complex +namespace: cellular_component +def: "A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates." [GOC:krc, ISBN:0879697393] +is_a: GO:0005681 ! spliceosomal complex +relationship: has_part GO:0005682 ! U5 snRNP +relationship: has_part GO:0005686 ! U2 snRNP +relationship: has_part GO:0005687 ! U4 snRNP +relationship: has_part GO:0005688 ! U6 snRNP +relationship: has_part GO:0071024 ! SL snRNP +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071024 +name: SL snRNP +namespace: cellular_component +def: "A ribonucleoprotein complex that contains spliced leader (SL) RNA." [GOC:krc, ISBN:0879697393] +is_a: GO:0097525 ! spliceosomal snRNP complex +created_by: mah +creation_date: 2009-07-30T12:00:35Z + +[Term] +id: GO:0071025 +name: RNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant RNAs." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "aberrant RNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "RNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0006401 ! RNA catabolic process +created_by: krc +creation_date: 2009-07-28T03:10:28Z + +[Term] +id: GO:0071026 +name: cytoplasmic RNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "cytoplasmic aberrant RNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "cytoplasmic RNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0071025 ! RNA surveillance +intersection_of: GO:0071025 ! RNA surveillance +intersection_of: occurs_in GO:0005737 ! cytoplasm +relationship: occurs_in GO:0005737 ! cytoplasm +created_by: krc +creation_date: 2009-07-28T03:14:03Z + +[Term] +id: GO:0071027 +name: nuclear RNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear aberrant RNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear RNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0071025 ! RNA surveillance +intersection_of: GO:0071025 ! RNA surveillance +intersection_of: occurs_in GO:0005634 ! nucleus +relationship: occurs_in GO:0005634 ! nucleus +created_by: krc +creation_date: 2009-07-28T03:45:02Z + +[Term] +id: GO:0071028 +name: nuclear mRNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear aberrant mRNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear mRNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process +is_a: GO:0071027 ! nuclear RNA surveillance +created_by: krc +creation_date: 2009-07-28T04:14:29Z + +[Term] +id: GO:0071029 +name: nuclear ncRNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear aberrant ncRNA catabolic process" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear ncRNA quality control" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0034661 ! ncRNA catabolic process +is_a: GO:0071027 ! nuclear RNA surveillance +created_by: krc +creation_date: 2009-07-28T04:22:31Z + +[Term] +id: GO:0071030 +name: nuclear mRNA surveillance of spliceosomal pre-mRNA splicing +namespace: biological_process +def: "The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear mRNA quality control of incorrectly spliced pre-mRNA" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear RNA catabolic process of incorrectly spliced pre-mRNA" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0071028 ! nuclear mRNA surveillance +relationship: has_part GO:0071042 ! nuclear polyadenylation-dependent mRNA catabolic process +created_by: krc +creation_date: 2009-07-28T04:24:04Z + +[Term] +id: GO:0071031 +name: nuclear mRNA surveillance of mRNA 3'-end processing +namespace: biological_process +def: "The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear mRNA catabolic process of mRNA with aberrant 3'-ends" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear mRNA quality control of mRNAs with aberrant 3'-ends" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0071028 ! nuclear mRNA surveillance +relationship: has_part GO:0071042 ! nuclear polyadenylation-dependent mRNA catabolic process +created_by: krc +creation_date: 2009-07-28T04:29:17Z + +[Term] +id: GO:0071032 +name: nuclear mRNA surveillance of mRNP export +namespace: biological_process +def: "The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm." [GOC:dgf, GOC:krc, PMID:18644474] +synonym: "nuclear mRNA catabolic process of mRNAs in aberrant mRNPs" EXACT [GOC:dgf, GOC:krc] +synonym: "nuclear mRNA quality control of mRNAs in aberrant mRNPs" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0071028 ! nuclear mRNA surveillance +created_by: krc +creation_date: 2009-07-28T04:31:57Z + +[Term] +id: GO:0071033 +name: nuclear retention of pre-mRNA at the site of transcription +namespace: biological_process +def: "The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription." [GOC:dgf, GOC:krc, PMID:11586364, PMID:12417728, PMID:14718167, PMID:18644474] +is_a: GO:0008298 ! intracellular mRNA localization +relationship: occurs_in GO:0005634 ! nucleus +relationship: part_of GO:0071028 ! nuclear mRNA surveillance +created_by: krc +creation_date: 2009-07-28T04:35:54Z + +[Term] +id: GO:0071034 +name: CUT catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs)." [GOC:dgf, GOC:krc] +synonym: "cryptic unstable transcript catabolic process" EXACT [GOC:dgf, GOC:krc] +is_a: GO:0034661 ! ncRNA catabolic process +is_a: GO:0071043 ! CUT metabolic process +created_by: krc +creation_date: 2009-07-29T12:38:04Z + +[Term] +id: GO:0071035 +name: nuclear polyadenylation-dependent rRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA." [GOC:dgf, GOC:krc, PMID:15173578, PMID:15572680, PMID:15935758, PMID:17652137, PMID:18591258] +synonym: "nuclear poly(A)-dependent rRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0016075 ! rRNA catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +created_by: krc +creation_date: 2009-07-29T12:42:39Z + +[Term] +id: GO:0071036 +name: nuclear polyadenylation-dependent snoRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA." [GOC:dgf, GOC:krc, PMID:15935758] +synonym: "nuclear poly(A)-dependent snoRNA catabolic process" RELATED [GOC:tb] +is_a: GO:0016077 ! snoRNA catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +relationship: has_part GO:0071050 ! snoRNA polyadenylation +created_by: krc +creation_date: 2009-07-29T01:04:44Z + +[Term] +id: GO:0071037 +name: nuclear polyadenylation-dependent snRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA." [GOC:dgf, GOC:krc] +synonym: "nuclear poly(A)-dependent snRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0016076 ! snRNA catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +created_by: krc +creation_date: 2009-07-29T01:07:18Z + +[Term] +id: GO:0071038 +name: nuclear polyadenylation-dependent tRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA." [GOC:dgf, GOC:krc] +synonym: "nuclear poly(A)-dependent tRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0016078 ! tRNA catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +created_by: krc +creation_date: 2009-07-29T01:08:14Z + +[Term] +id: GO:0071039 +name: nuclear polyadenylation-dependent CUT catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT." [GOC:dgf, GOC:krc, PMID:15935759, PMID:16973436, PMID:16973437, PMID:18007593, PMID:18591258] +synonym: "nuclear poly(A)-dependent CUT catabolic process" RELATED [GOC:vw] +is_a: GO:0071034 ! CUT catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +created_by: krc +creation_date: 2009-07-29T01:10:34Z + +[Term] +id: GO:0071040 +name: nuclear polyadenylation-dependent antisense transcript catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript." [GOC:dgf, GOC:krc, PMID:18022365] +synonym: "nuclear poly(A)-dependent antisense transcript catabolic process" RELATED [GOC:vw] +is_a: GO:0071041 ! antisense RNA transcript catabolic process +is_a: GO:0071046 ! nuclear polyadenylation-dependent ncRNA catabolic process +created_by: krc +creation_date: 2009-07-29T01:25:21Z + +[Term] +id: GO:0071041 +name: antisense RNA transcript catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product." [GOC:dgf, GOC:krc] +is_a: GO:0034661 ! ncRNA catabolic process +is_a: GO:0042868 ! antisense RNA metabolic process +created_by: krc +creation_date: 2009-07-29T01:39:36Z + +[Term] +id: GO:0071042 +name: nuclear polyadenylation-dependent mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA." [GOC:dgf, GOC:krc, PMID:15145828, PMID:15828860, PMID:16431988, PMID:17643380, PMID:18000032, PMID:18644474] +synonym: "nuclear poly(A)-dependent mRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0071047 ! polyadenylation-dependent mRNA catabolic process +created_by: krc +creation_date: 2009-07-29T02:06:19Z + +[Term] +id: GO:0071043 +name: CUT metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome." [GOC:dgf, GOC:krc, PMID:15935759, PMID:16973436] +is_a: GO:0034660 ! ncRNA metabolic process +created_by: krc +creation_date: 2009-07-29T02:31:31Z + +[Term] +id: GO:0071044 +name: histone mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA)." [GOC:dgf, GOC:krc, PMID:17179095, PMID:17855393] +is_a: GO:0000956 ! nuclear-transcribed mRNA catabolic process +is_a: GO:0008334 ! histone mRNA metabolic process +created_by: krc +creation_date: 2009-07-30T09:48:10Z + +[Term] +id: GO:0071045 +name: nuclear histone mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus." [GOC:dgf, GOC:krc, PMID:17179095, PMID:17855393] +is_a: GO:0071044 ! histone mRNA catabolic process +created_by: krc +creation_date: 2009-07-30T09:52:44Z + +[Term] +id: GO:0071046 +name: nuclear polyadenylation-dependent ncRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA." [GOC:dgf, GOC:jl, GOC:krc, PMID:17410208] +synonym: "nuclear poly(A)-dependent ncRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0043634 ! polyadenylation-dependent ncRNA catabolic process +is_a: GO:0071029 ! nuclear ncRNA surveillance +created_by: krc +creation_date: 2009-08-06T02:14:53Z + +[Term] +id: GO:0071047 +name: polyadenylation-dependent mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA." [GOC:dgf, GOC:krc] +synonym: "poly(A)-dependent mRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0006402 ! mRNA catabolic process +is_a: GO:0043633 ! polyadenylation-dependent RNA catabolic process +relationship: has_part GO:0006378 ! mRNA polyadenylation +created_by: krc +creation_date: 2009-08-07T09:57:56Z + +[Term] +id: GO:0071048 +name: nuclear retention of unspliced pre-mRNA at the site of transcription +namespace: biological_process +def: "The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription." [GOC:dgf, GOC:krc, PMID:14718167] +is_a: GO:0071033 ! nuclear retention of pre-mRNA at the site of transcription +relationship: part_of GO:0071030 ! nuclear mRNA surveillance of spliceosomal pre-mRNA splicing +created_by: krc +creation_date: 2009-08-11T02:19:03Z + +[Term] +id: GO:0071049 +name: nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription +namespace: biological_process +def: "The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription." [GOC:dgf, GOC:krc, PMID:11586364, PMID:12417728] +is_a: GO:0071033 ! nuclear retention of pre-mRNA at the site of transcription +relationship: part_of GO:0071031 ! nuclear mRNA surveillance of mRNA 3'-end processing +created_by: krc +creation_date: 2009-08-11T02:40:56Z + +[Term] +id: GO:0071050 +name: snoRNA polyadenylation +namespace: biological_process +def: "The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA molecule. In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation." [GOC:dgf, GOC:krc, PMID:18951092] +is_a: GO:0031126 ! snoRNA 3'-end processing +is_a: GO:0043629 ! ncRNA polyadenylation +created_by: krc +creation_date: 2009-08-25T03:33:44Z + +[Term] +id: GO:0071051 +name: polyadenylation-dependent snoRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA." [GOC:dgf, GOC:krc, PMID:18951092] +synonym: "poly(A)-dependent snoRNA 3'-end processing" RELATED [GOC:vw] +is_a: GO:0031126 ! snoRNA 3'-end processing +relationship: has_part GO:0071050 ! snoRNA polyadenylation +created_by: krc +creation_date: 2009-08-25T03:47:24Z + +[Term] +id: GO:0071052 +name: alpha9-beta1 integrin-ADAM1 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1." [PMID:11882657] +synonym: "ITGA9-ITGB1-ADAM1 complex" NARROW [CORUM:2964] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T03:55:15Z + +[Term] +id: GO:0071053 +name: alpha9-beta1 integrin-ADAM2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2." [PMID:11882657] +synonym: "ITGA9-ITGB1-ADAM2 complex" NARROW [CORUM:2441] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T03:58:22Z + +[Term] +id: GO:0071054 +name: alpha9-beta1 integrin-ADAM3 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3." [PMID:11882657] +synonym: "ITGA9-ITGB1-ADAM3 complex" NARROW [CORUM:2965] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T03:59:02Z + +[Term] +id: GO:0071055 +name: alpha9-beta1 integrin-ADAM9 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9." [PMID:11882657] +synonym: "ITGA9-ITGB1-ADAM9 complex" NARROW [CORUM:2440] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T03:59:24Z + +[Term] +id: GO:0071056 +name: alpha9-beta1 integrin-ADAM15 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15." [PMID:11882657] +synonym: "ITGA9-ITGB1-ADAM15 complex" NARROW [CORUM:2445] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T03:59:49Z + +[Term] +id: GO:0071057 +name: alphav-beta3 integrin-ADAM15 complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15." [PMID:10944520, PMID:11882657] +synonym: "ITGAV-ITGB3-ADAM15 complex" NARROW [CORUM:2359] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:00:14Z + +[Term] +id: GO:0071058 +name: alpha3-beta1 integrin-CD151 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151." [PMID:10811835, PMID:11884516] +synonym: "ITGA3-ITGB1-CD151 complex" NARROW [CORUM:2400] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:00:39Z + +[Term] +id: GO:0071059 +name: alpha6-beta1 integrin-CD151 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151." [PMID:11884516] +synonym: "ITGA6-ITGB1-CD151 complex" NARROW [CORUM:2411] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:01:23Z + +[Term] +id: GO:0071060 +name: alpha7-beta1 integrin-CD151 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151." [PMID:11884516] +synonym: "ITGA7-ITGB1-CD151 complex" NARROW [CORUM:2395] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:02:01Z + +[Term] +id: GO:0071061 +name: alpha6-beta4 integrin-CD151 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151." [PMID:10811835] +synonym: "ITGA6-ITGB4-CD151 complex" NARROW [CORUM:2320] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:02:37Z + +[Term] +id: GO:0071062 +name: alphav-beta3 integrin-vitronectin complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin." [PMID:10835423] +synonym: "ITGAV-ITGB3-VTN complex" NARROW [CORUM:2826] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:02:57Z + +[Term] +id: GO:0071063 +name: sensory perception of wind +namespace: biological_process +def: "The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal." [GOC:mah, PMID:19279637] +synonym: "perception of wind" EXACT [GOC:mah] +synonym: "sensory perception of air flow" EXACT [GOC:mah, PMID:19279637] +is_a: GO:0050954 ! sensory perception of mechanical stimulus +created_by: mah +creation_date: 2009-11-04T02:40:34Z + +[Term] +id: GO:0071064 +name: alphaE-beta7 integrin-E-cadherin complex +namespace: cellular_component +def: "A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin." [PMID:10837471] +synonym: "ITGAE-ITGB7-CDH1 complex" NARROW [CORUM:1834] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:03:37Z + +[Term] +id: GO:0071065 +name: alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1." [PMID:10209034] +synonym: "ITGA9-ITGB1-VCAM1 complex" NARROW [CORUM:2442] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:04:01Z + +[Term] +id: GO:0071066 +name: detection of mechanical stimulus involved in sensory perception of wind +namespace: biological_process +def: "The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal." [GOC:dos, GOC:mah, PMID:19279637] +synonym: "detection of mechanical stimulus involved in sensory perception of air flow" EXACT [GOC:mah] +synonym: "detection of wind" EXACT [GOC:mah] +synonym: "perception of wind, detection of mechanical stimulus" EXACT [GOC:mah] +synonym: "perception of wind, sensory detection of mechanical stimulus" EXACT [GOC:mah] +synonym: "perception of wind, sensory transduction of mechanical stimulus" EXACT [GOC:mah] +synonym: "sensory detection of mechanical stimulus during perception of wind" EXACT [GOC:mah] +synonym: "sensory transduction of mechanical stimulus during perception of wind" EXACT [GOC:mah] +synonym: "sensory transduction of wind" EXACT [GOC:mah] +is_a: GO:0050877 ! nervous system process +is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception +intersection_of: GO:0050982 ! detection of mechanical stimulus +intersection_of: part_of GO:0071063 ! sensory perception of wind +relationship: part_of GO:0071063 ! sensory perception of wind +created_by: mah +creation_date: 2009-11-04T02:47:36Z + +[Term] +id: GO:0071067 +name: alphav-beta3 integrin-ADAM23 complex +namespace: cellular_component +def: "A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23." [PMID:10749942] +synonym: "ITGAV-ITGB3-ADAM23 complex" NARROW [CORUM:2364] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:04:40Z + +[Term] +id: GO:0071068 +name: alpha9-beta1 integrin-ADAM12 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12." [PMID:10944520] +synonym: "ITGA9-ITGB1-ADAM12 complex" NARROW [CORUM:2447] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:05:15Z + +[Term] +id: GO:0071069 +name: alpha4-beta1 integrin-thrombospondin-1 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1." [PMID:11980922] +synonym: "ITGA4-ITGB1-THBS1 complex" NARROW [CORUM:2426] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:05:35Z + +[Term] +id: GO:0071070 +name: alpha4-beta1 integrin-thrombospondin-2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2." [PMID:11980922] +synonym: "ITGA4-ITGB1-THBS2 complex" NARROW [CORUM:2428] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-03T04:05:56Z + +[Term] +id: GO:0071071 +name: regulation of phospholipid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids." [GOC:mah] +synonym: "regulation of phospholipid anabolism" EXACT [GOC:mah] +synonym: "regulation of phospholipid biosynthesis" EXACT [GOC:mah] +synonym: "regulation of phospholipid formation" EXACT [GOC:mah] +synonym: "regulation of phospholipid synthesis" EXACT [GOC:mah] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008654 ! phospholipid biosynthetic process +relationship: regulates GO:0008654 ! phospholipid biosynthetic process +created_by: mah +creation_date: 2009-11-04T03:05:11Z + +[Term] +id: GO:0071072 +name: negative regulation of phospholipid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids." [GOC:mah] +synonym: "down regulation of phospholipid biosynthetic process" EXACT [GOC:mah] +synonym: "down-regulation of phospholipid biosynthetic process" EXACT [GOC:ma] +synonym: "downregulation of phospholipid biosynthetic process" EXACT [GOC:mah] +synonym: "inhibition of phospholipid biosynthetic process" NARROW [GOC:mah] +synonym: "negative regulation of phospholipid anabolism" EXACT [GOC:mah] +synonym: "negative regulation of phospholipid biosynthesis" EXACT [GOC:mah] +synonym: "negative regulation of phospholipid formation" EXACT [GOC:mah] +synonym: "negative regulation of phospholipid synthesis" EXACT [GOC:mah] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008654 ! phospholipid biosynthetic process +relationship: negatively_regulates GO:0008654 ! phospholipid biosynthetic process +created_by: mah +creation_date: 2009-11-04T03:14:08Z + +[Term] +id: GO:0071073 +name: positive regulation of phospholipid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids." [GOC:mah] +synonym: "activation of phospholipid biosynthetic process" NARROW [GOC:mah] +synonym: "positive regulation of phospholipid anabolism" EXACT [GOC:mah] +synonym: "positive regulation of phospholipid biosynthesis" EXACT [GOC:mah] +synonym: "positive regulation of phospholipid formation" EXACT [GOC:mah] +synonym: "positive regulation of phospholipid synthesis" EXACT [GOC:mah] +synonym: "stimulation of phospholipid biosynthetic process" NARROW [GOC:mah] +synonym: "up regulation of phospholipid biosynthetic process" EXACT [GOC:mah] +synonym: "up-regulation of phospholipid biosynthetic process" EXACT [GOC:mah] +synonym: "upregulation of phospholipid biosynthetic process" EXACT [GOC:mah] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008654 ! phospholipid biosynthetic process +relationship: positively_regulates GO:0008654 ! phospholipid biosynthetic process +created_by: mah +creation_date: 2009-11-04T03:18:51Z + +[Term] +id: GO:0071074 +name: eukaryotic initiation factor eIF2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation." [GOC:hjd] +is_a: GO:0031369 ! translation initiation factor binding +created_by: mah +creation_date: 2009-11-06T01:39:02Z + +[Term] +id: GO:0071075 +name: CUGBP1-eIF2 complex +namespace: cellular_component +def: "A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation." [PMID:16931514] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-11-06T01:43:30Z + +[Term] +id: GO:0071076 +name: RNA 3' uridylation +namespace: biological_process +def: "The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule." [GOC:vw, PMID:19430462] +is_a: GO:0031123 ! RNA 3'-end processing +created_by: mah +creation_date: 2009-11-06T02:41:23Z + +[Term] +id: GO:0071077 +name: adenosine 3',5'-bisphosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other." [GOC:mah] +synonym: "adenosine 3',5'-diphosphate transporter activity" EXACT [PubChem_Compound:159296] +synonym: "adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity" EXACT [PubChem_Compound:159296] +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +relationship: part_of GO:0071106 ! adenosine 3',5'-bisphosphate transmembrane transport +created_by: mah +creation_date: 2009-11-06T03:44:14Z + +[Term] +id: GO:0071078 +name: fibronectin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion." [PMID:10684262] +synonym: "FN-TGM2 complex" NARROW [CORUM:2375] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:42:22Z + +[Term] +id: GO:0071079 +name: alpha2-beta1 integrin-chondroadherin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin." [PMID:9281592] +synonym: "ITGA2-ITGB1-CHAD complex" NARROW [CORUM:2430] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:42:55Z + +[Term] +id: GO:0071080 +name: alpha3-beta1 integrin-basigin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin." [PMID:9360995] +synonym: "ITGA3-ITGB1-BSG complex" NARROW [CORUM:2398] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:43:26Z + +[Term] +id: GO:0071081 +name: alpha3-beta1 integrin-CD63 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63." [PMID:7629079] +synonym: "ITGA3-ITGB1-CD63 complex" NARROW [CORUM:2399] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:43:43Z + +[Term] +id: GO:0071082 +name: alpha9-beta1 integrin-tenascin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin." [PMID:9565552] +synonym: "ITGA9-ITGB1-TNC complex" NARROW [CORUM:2443] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:43:58Z + +[Term] +id: GO:0071083 +name: alphaV-beta3 integrin-CD47-FCER2 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2)." [PMID:10037797] +synonym: "ITGAV-ITGB3-CD447-FCER2 complex" NARROW [CORUM:2355] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:44:20Z + +[Term] +id: GO:0071084 +name: alpha2-beta1 integrin-CD47 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47." [PMID:10397731] +synonym: "ITGA2-ITGB1-CD47 complex" NARROW [CORUM:2429] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:44:35Z + +[Term] +id: GO:0071085 +name: alphaIIb-beta3 integrin-CD9 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9." [PMID:10429193] +synonym: "ITGA2b-ITGB3-CD9 complex" NARROW [CORUM:2370] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:44:52Z + +[Term] +id: GO:0071086 +name: alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib." [PMID:10429193] +synonym: "ITGA2b-ITGB3-CD9-GP1b-CD47 complex" NARROW [CORUM:2872] +is_a: GO:0090665 ! glycoprotein complex +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:45:08Z + +[Term] +id: GO:0071087 +name: alpha11-beta1 integrin-collagen type I complex +namespace: cellular_component +def: "A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen." [PMID:10464311] +synonym: "ITGA11-ITGB1-COL1A1 complex" NARROW [CORUM:3059] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:45:27Z + +[Term] +id: GO:0071088 +name: alpha5-beta1 integrin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase." [PMID:10684262] +synonym: "ITGA5-ITGB1-TGM2 complex" NARROW [CORUM:2433] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:45:47Z + +[Term] +id: GO:0071089 +name: alphaV-beta3 integrin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase." [PMID:10684262] +synonym: "ITGAV-ITGB3-TGM2 complex" NARROW [CORUM:3095] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:46:02Z + +[Term] +id: GO:0071090 +name: alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase." [PMID:10684262] +synonym: "ITGA2b-ITGB3-FN1-TGM2 complex" NARROW [CORUM:2376] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:46:24Z + +[Term] +id: GO:0071091 +name: alpha1-beta1 integrin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase." [PMID:10684262] +synonym: "ITGA1-ITGB1-TGM2 complex" NARROW [CORUM:2894] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:46:44Z + +[Term] +id: GO:0071092 +name: alpha3-beta1 integrin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase." [PMID:10684262] +synonym: "ITGA3-ITGB1-TGM2 complex" NARROW [CORUM:2402] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:47:04Z + +[Term] +id: GO:0071093 +name: alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase." [PMID:10684262] +synonym: "ITGA5-ITGB1-FN1-TGM2 complex" NARROW [CORUM:2383] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:47:22Z + +[Term] +id: GO:0071094 +name: alpha6-beta4 integrin-CD9 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9." [PMID:10711425] +synonym: "ITGA6-ITGB4-CD9 complex" NARROW [CORUM:2770] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:47:44Z + +[Term] +id: GO:0071095 +name: alpha3-beta1 integrin-thrombospondin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin." [PMID:11358957] +synonym: "ITGA3-ITGB1-THBS1 complex" NARROW [CORUM:2401] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:48:03Z + +[Term] +id: GO:0071096 +name: alphaV-beta3 integrin-gelsolin complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin." [PMID:11577104] +synonym: "ITGAV-ITGB3-Gsn complex" NARROW [CORUM:2360] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:49:31Z + +[Term] +id: GO:0071097 +name: alphaV-beta3 integrin-paxillin-Pyk2 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2." [PMID:11683411] +synonym: "ITGAV-ITGB3-PXN-PTK2b complex" NARROW [CORUM:2363] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:51:52Z + +[Term] +id: GO:0071098 +name: alpha6-beta4 integrin-Fyn complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn." [PMID:11684709] +synonym: "ITGA6-ITGB4-FYN complex" NARROW [CORUM:2321] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:52:10Z + +[Term] +id: GO:0071099 +name: alphaV-beta6 integrin-TGFbeta-3 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3)." [PMID:11821050] +synonym: "ITGAV-ITGB6-TFGB3 complex" NARROW [CORUM:2353] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:52:27Z + +[Term] +id: GO:0071100 +name: alphaV-beta8 integrin-MMP14-TGFbeta-1 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1)." [PMID:11970960] +synonym: "ITGAV-ITGB8-MMP14-TGFB1 complex" NARROW [CORUM:2342] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:52:43Z + +[Term] +id: GO:0071101 +name: alpha4-beta1 integrin-JAM2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2." [PMID:12070135] +synonym: "ITGA4-ITGB1-JAM2 complex" NARROW [CORUM:2422] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:52:59Z + +[Term] +id: GO:0071102 +name: alpha4-beta1 integrin-paxillin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin." [PMID:12221126] +synonym: "ITGA4-ITGB1-PXN complex" NARROW [CORUM:2425] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-06T04:53:22Z + +[Term] +id: GO:0071103 +name: DNA conformation change +namespace: biological_process +def: "A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule." [GOC:mah] +subset: goslim_metagenomics +synonym: "DNA conformation modification" EXACT [GOC:mah] +is_a: GO:0051276 ! chromosome organization +created_by: mah +creation_date: 2009-11-09T11:36:34Z + +[Term] +id: GO:0071104 +name: response to interleukin-9 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus." [GOC:mah, GOC:yaf] +synonym: "response to IL-9" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-11-09T12:50:25Z + +[Term] +id: GO:0071105 +name: response to interleukin-11 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus." [GOC:mah, GOC:yaf] +synonym: "response to IL-11" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine +created_by: mah +creation_date: 2009-11-09T12:52:51Z + +[Term] +id: GO:0071106 +name: adenosine 3',5'-bisphosphate transmembrane transport +namespace: biological_process +def: "The process in which adenosine 3',5'-bisphosphate is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "adenosine 3',5'-bisphosphate membrane transport" EXACT [] +synonym: "adenosine 3',5'-diphosphate transport" EXACT [PubChem_Compound:159296] +synonym: "adenosine 3'-phosphate-5'-phosphate transmembrane transport" EXACT [PubChem_Compound:159296] +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: mah +creation_date: 2009-11-12T10:40:49Z + +[Term] +id: GO:0071107 +name: response to parathyroid hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus." [GOC:mah, GOC:yaf] +synonym: "response to parathyroid hormone stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +created_by: mah +creation_date: 2009-11-12T10:58:45Z + +[Term] +id: GO:0071108 +name: protein K48-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein." [GOC:mah] +is_a: GO:0016579 ! protein deubiquitination +created_by: mah +creation_date: 2009-11-12T01:34:01Z + +[Term] +id: GO:0071109 +name: superior temporal gyrus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus." [FMA:61905, GOC:BHF, GOC:mah, PMID:11484000] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0021987 ! cerebral cortex development +created_by: mah +creation_date: 2009-11-12T02:19:23Z + +[Term] +id: GO:0071110 +name: histone biotinylation +namespace: biological_process +def: "The modification of a histone by the addition of a biotinyl group." [GOC:rph, PMID:14613969, PMID:19019041] +is_a: GO:0009305 ! protein biotinylation +is_a: GO:0016570 ! histone modification +created_by: mah +creation_date: 2009-11-13T01:22:59Z + +[Term] +id: GO:0071111 +name: cyclic-guanylate-specific phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+)." [EC:3.1.4.52, RHEA:24902] +synonym: "c-di-GMP phosphodiesterase activity" EXACT [EC:3.1.4.52] +synonym: "c-di-GMP-specific phosphodiesterase activity" EXACT [EC:3.1.4.52] +synonym: "cyclic bis(3->5')diguanylate phosphodiesterase activity" EXACT [EC:3.1.4.52] +synonym: "PDEA1" RELATED [EC:3.1.4.52] +synonym: "phosphodiesterase A1 activity" RELATED [EC:3.1.4.52] +synonym: "VieA" RELATED [EC:3.1.4.52] +xref: EC:3.1.4.52 +xref: KEGG_REACTION:R08991 +xref: MetaCyc:RXN0-4181 +xref: RHEA:24902 +is_a: GO:0008081 ! phosphoric diester hydrolase activity +created_by: mah +creation_date: 2009-11-13T02:10:39Z + +[Term] +id: GO:0071112 +name: alpha4-beta4 integrin-EMILIN-1 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN)." [PMID:12456677] +synonym: "ITGA4-ITGB4-EMILIN1 complex" NARROW [CORUM:2417] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:17:11Z + +[Term] +id: GO:0071113 +name: alphaIIb-beta3 integrin-ICAM-4 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4." [PMID:12477717] +synonym: "ITGAIIb-ITGB3-ICAM4 complex" NARROW [CORUM:3115] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:17:59Z + +[Term] +id: GO:0071114 +name: alphaV-beta3 integrin-tumstatin complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen." [PMID:12682293] +synonym: "ITGAV-ITGB3-COL4A3 complex" NARROW [CORUM:2365] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:18:29Z + +[Term] +id: GO:0071115 +name: alpha5-beta1 integrin-endostatin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen." [PMID:12682293] +synonym: "ITGA5-ITGB1-CAL4A3 complex" NARROW [CORUM:2853] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:18:57Z + +[Term] +id: GO:0071116 +name: alpha6-beta1 integrin-CYR61 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis." [PMID:12826661] +synonym: "ITGA6-ITGB1-CYR61 complex" NARROW [CORUM:2437] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:19:23Z + +[Term] +id: GO:0071117 +name: alpha5-beta1 integrin-fibronectin-NOV complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV." [PMID:12902636] +synonym: "ITGA5-ITGB1-FN-1-NOV complex" NARROW [CORUM:2850] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:19:52Z + +[Term] +id: GO:0071118 +name: alphaV-beta3 integrin-NOV complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV." [PMID:12902636] +synonym: "ITGAV-ITGB3-FN-1-NOV complex" NARROW [CORUM:2849] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:20:20Z + +[Term] +id: GO:0071119 +name: alpha7-beta1 integrin-nicotinamide riboside kinase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP)." [PMID:12941630] +synonym: "ITGA7-ITGB1-ITGB1BP3 complex" NARROW [CORUM:2397] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:20:44Z + +[Term] +id: GO:0071120 +name: alpha4-beta1 integrin-CD47 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47." [PMID:15292185] +synonym: "ITGA4-ITGB1-CB47 complex" NARROW [CORUM:2423] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:21:10Z + +[Term] +id: GO:0071121 +name: alpha9-beta1 integrin-VEGF-D complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D." [PMID:15590642] +synonym: "ITGA9-ITGB1-FIGF complex" NARROW [CORUM:2446] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:21:37Z + +[Term] +id: GO:0071122 +name: alpha9-beta1 integrin-VEGF-A complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A." [PMID:17363377] +synonym: "ITGA9-ITGB1-VEGFA complex" NARROW [CORUM:2972] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:22:01Z + +[Term] +id: GO:0071123 +name: alpha9-beta1 integrin-VEGF-C complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C." [PMID:15590642] +synonym: "ITGA9-ITGB1-VEGFC complex" NARROW [CORUM:2971] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:22:27Z + +[Term] +id: GO:0071124 +name: alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2." [PMID:15592458] +synonym: "ITGA1-ITGB1-PTPN2 complex" NARROW [CORUM:2435] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:22:51Z + +[Term] +id: GO:0071125 +name: alphaV-beta3 integrin-EGFR complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor." [PMID:15834425] +synonym: "ITGAV-ITGB3-EGFR complex" NARROW [CORUM:2369] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:23:18Z + +[Term] +id: GO:0071126 +name: alphaV-beta6 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin." [PMID:16005200] +synonym: "ITGAV-ITGB6-SPP1 complex" NARROW [CORUM:2352] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:23:43Z + +[Term] +id: GO:0071127 +name: alpha9-beta1 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin." [PMID:16005200] +synonym: "ITGA9-ITGB1-SPP1 complex" NARROW [CORUM:3111] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:24:09Z + +[Term] +id: GO:0071128 +name: alpha5-beta1 integrin-osteopontin complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin." [PMID:16005200] +synonym: "ITGA5-ITGB1-SPP1 complex" NARROW [CORUM:3112] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:24:43Z + +[Term] +id: GO:0071129 +name: alphaV-beta3 integrin-LPP3 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3." [PMID:16099422] +synonym: "ITGAV-ITGB3-PPAP2B complex" NARROW [CORUM:2366] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:25:17Z + +[Term] +id: GO:0071130 +name: alpha5-beta1 integrin-LPP3 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3." [PMID:16099422] +synonym: "ITGA5-ITGB1-PPAP2B complex" NARROW [CORUM:2386] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:25:47Z + +[Term] +id: GO:0071131 +name: alphaV-beta3 integrin-laminin alpha-4 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4." [PMID:16824487] +synonym: "ITGAV-ITGB3-LAMA4 complex" NARROW [CORUM:2374] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:26:11Z + +[Term] +id: GO:0071132 +name: alphaX-beta2 integrin-ICAM-4 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4." [PMID:16985175] +synonym: "ITGAX-ITGB2-ICAM4 complex" NARROW [CORUM:3114] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:28:30Z + +[Term] +id: GO:0071133 +name: alpha9-beta1 integrin-ADAM8 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8." [PMID:16995821] +synonym: "ITGA9-ITGB1-ADAM8 complex" NARROW [CORUM:2989] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:28:49Z + +[Term] +id: GO:0071134 +name: alpha9-beta1 integrin-thrombospondin-1 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1." [PMID:17413041] +synonym: "ITGA9-ITGB1-THBS1 complex" NARROW [CORUM:2967] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:29:07Z + +[Term] +id: GO:0071135 +name: alpha7-beta1 integrin-focal adhesion kinase complex +namespace: cellular_component +def: "A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase." [PMID:17598176] +synonym: "ITGA7-ITGB1-PTK2 complex" NARROW [CORUM:3106] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:29:24Z + +[Term] +id: GO:0071136 +name: alpha7-beta1 integrin-laminin alpha-2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2." [PMID:17598176] +synonym: "ITGA7-ITGB1-LAMA2 complex" NARROW [CORUM:3105] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:29:42Z + +[Term] +id: GO:0071137 +name: alphaV-beta3 integrin-CD98 complex +namespace: cellular_component +def: "A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98." [PMID:18032696] +synonym: "ITGAV-ITGB3-SLC3A2 complex" NARROW [CORUM:3103] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:29:59Z + +[Term] +id: GO:0071138 +name: alpha5-beta5-fibronectin-SFRP2 complex +namespace: cellular_component +def: "A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2." [PMID:14709558] +synonym: "ITGA5-ITGB5-FN-1-SFRP2 complex" NARROW [CORUM:2388] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-13T02:30:31Z + +[Term] +id: GO:0071139 +name: resolution of recombination intermediates +namespace: biological_process +def: "The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, GOC:mah, GOC:vw] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006310 ! DNA recombination +created_by: mah +creation_date: 2009-11-16T12:02:21Z + +[Term] +id: GO:0071140 +name: resolution of mitotic recombination intermediates +namespace: biological_process +def: "The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, GOC:mah, GOC:vw] +is_a: GO:0071139 ! resolution of recombination intermediates +relationship: part_of GO:0006312 ! mitotic recombination +created_by: mah +creation_date: 2009-11-16T12:06:05Z + +[Term] +id: GO:0071141 +name: SMAD protein complex +namespace: cellular_component +def: "A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven." [GOC:bhm, GOC:mah, PMID:9670020] +synonym: "SMAD complex" EXACT [GOC:mah] +is_a: GO:0005622 ! intracellular +is_a: GO:0032991 ! protein-containing complex +created_by: mah +creation_date: 2009-11-16T02:28:59Z + +[Term] +id: GO:0071142 +name: homomeric SMAD protein complex +namespace: cellular_component +alt_id: GO:0071143 +def: "A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive." [GOC:bhm, GOC:mah, PMID:11779505, PMID:16322555, PMID:9670020] +synonym: "SMAD1 homotrimer complex" NARROW [] +synonym: "SMAD1 protein complex" NARROW [] +synonym: "SMAD2 homotrimer complex" NARROW [] +synonym: "SMAD2 protein complex" NARROW [] +synonym: "SMAD3 homotrimer complex" NARROW [CORUM:3003] +synonym: "SMAD3 protein complex" NARROW [] +xref: IntAct:EBI-10043504 +xref: IntAct:EBI-10043549 +xref: IntAct:EBI-10043574 +xref: IntAct:EBI-10043586 +xref: IntAct:EBI-10828213 +xref: IntAct:EBI-10828300 +is_a: GO:0071141 ! SMAD protein complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-11-16T02:41:19Z + +[Term] +id: GO:0071144 +name: heteromeric SMAD protein complex +namespace: cellular_component +alt_id: GO:0071145 +alt_id: GO:0071146 +def: "A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric." [GOC:bhm, GOC:mah, PMID:11779505, PMID:15350224, PMID:16322555, PMID:9389648, PMID:9670020] +synonym: "SMAD1-SMAD4 protein complex" NARROW [] +synonym: "SMAD2-SMAD3-SMAD4 protein complex" NARROW [] +synonym: "SMAD2-SMAD4 protein complex" NARROW [CORUM:3001] +synonym: "SMAD3-SMAD4 protein complex" NARROW [] +xref: IntAct:EBI-10021614 +xref: IntAct:EBI-10043452 +xref: IntAct:EBI-10127301 +xref: IntAct:EBI-10828741 +xref: IntAct:EBI-9692430 +xref: IntAct:EBI-9826270 +xref: IntAct:EBI-9826300 +xref: IntAct:EBI-9990274 +is_a: GO:0071141 ! SMAD protein complex +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +creation_date: 2009-11-16T02:44:37Z + +[Term] +id: GO:0071147 +name: TEAD-2 multiprotein complex +namespace: cellular_component +def: "A protein complex that consists of the DNA binding protein TEAD-2 bound to 12 other polypeptides including the transcriptional coactivator YAP, the multi-PDZ domain protein MPDZ (also called MUPP1), a 14-3-3 domain protein, and others." [GOC:mah, PMID:11358867] +xref: CORUM:2870 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-16T03:31:35Z + +[Term] +id: GO:0071148 +name: TEAD-1-YAP complex +namespace: cellular_component +def: "A transcription factor complex that is composed of the DNA binding protein TEAD-1 and the transcriptional coactivator YAP." [GOC:mah, PMID:11358867] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2009-11-16T03:38:43Z + +[Term] +id: GO:0071149 +name: TEAD-2-YAP complex +namespace: cellular_component +def: "A transcription factor complex that is composed of the DNA binding protein TEAD-2 and the transcriptional coactivator YAP." [GOC:mah, PMID:11358867] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2009-11-16T03:58:10Z + +[Term] +id: GO:0071150 +name: TEAD-3-YAP complex +namespace: cellular_component +def: "A transcription factor complex that is composed of the DNA binding protein TEAD-3 and the transcriptional coactivator YAP." [GOC:mah, PMID:11358867] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2009-11-16T03:58:31Z + +[Term] +id: GO:0071151 +name: TEAD-4-YAP complex +namespace: cellular_component +def: "A transcription factor complex that is composed of the DNA binding protein TEAD-4 and the transcriptional coactivator YAP." [GOC:mah, PMID:11358867] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2009-11-16T03:58:48Z + +[Term] +id: GO:0071152 +name: G-protein alpha(q)-synembrin complex +namespace: cellular_component +def: "A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein." [GOC:mah, PMID:12509430] +synonym: "Ric-8A G(q) alpha subunit complex" NARROW [CORUM:175] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-16T04:48:05Z + +[Term] +id: GO:0071153 +name: G-protein alpha(o)-synembrin complex +namespace: cellular_component +def: "A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein." [GOC:mah, PMID:12509430] +synonym: "Ric-8A G(o) alpha-1 subunit complex" NARROW [CORUM:172] +synonym: "Ric-8A G(o) alpha-2 subunit complex" NARROW [CORUM:174] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-16T04:55:00Z + +[Term] +id: GO:0071154 +name: G-protein alpha(i)1-synembrin complex +namespace: cellular_component +def: "A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein." [GOC:mah, PMID:12509430] +synonym: "Ric-8A G(i) alpha-1 subunit complex" NARROW [CORUM:170] +synonym: "Ric-8A G(i) alpha-2 subunit complex" RELATED [CORUM:171] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-16T04:57:46Z + +[Term] +id: GO:0071155 +name: G-protein alpha(13)-synembrin complex +namespace: cellular_component +def: "A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein." [GOC:mah, PMID:12509430] +synonym: "Ric-8A G alpha 13 subunit complex" NARROW [CORUM:176] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-16T05:01:55Z + +[Term] +id: GO:0071156 +name: regulation of cell cycle arrest +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases." [GOC:mah] +is_a: GO:0010564 ! regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007050 ! cell cycle arrest +relationship: regulates GO:0007050 ! cell cycle arrest +created_by: mah +creation_date: 2009-11-17T01:38:39Z + +[Term] +id: GO:0071157 +name: negative regulation of cell cycle arrest +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases." [GOC:mah] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045787 ! positive regulation of cell cycle +is_a: GO:0071156 ! regulation of cell cycle arrest +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007050 ! cell cycle arrest +relationship: negatively_regulates GO:0007050 ! cell cycle arrest +created_by: mah +creation_date: 2009-11-17T01:42:57Z + +[Term] +id: GO:0071158 +name: positive regulation of cell cycle arrest +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases." [GOC:mah] +is_a: GO:0071156 ! regulation of cell cycle arrest +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007050 ! cell cycle arrest +relationship: positively_regulates GO:0007050 ! cell cycle arrest +created_by: mah +creation_date: 2009-11-17T01:43:47Z + +[Term] +id: GO:0071159 +name: NF-kappaB complex +namespace: cellular_component +def: "A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression." [ISBN:0849327946] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2009-11-17T02:03:34Z + +[Term] +id: GO:0071160 +name: cyanophycin synthetase activity (L-aspartate-adding) +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp." [EC:6.3.2.29] +xref: EC:6.3.2.29 +is_a: GO:0043860 ! cyanophycin synthetase activity +created_by: mah +creation_date: 2009-11-17T05:18:17Z + +[Term] +id: GO:0071161 +name: cyanophycin synthetase activity (L-arginine-adding) +namespace: molecular_function +def: "Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1." [EC:6.3.2.30] +xref: EC:6.3.2.30 +is_a: GO:0043860 ! cyanophycin synthetase activity +created_by: mah +creation_date: 2009-11-17T05:19:54Z + +[Term] +id: GO:0071162 +name: CMG complex +namespace: cellular_component +def: "A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication." [GOC:rb, PMID:19228417] +synonym: "unwindosome" EXACT [PMID:19228417] +is_a: GO:0031261 ! DNA replication preinitiation complex +relationship: has_part GO:0000811 ! GINS complex +relationship: part_of GO:0000228 ! nuclear chromosome +created_by: mah +creation_date: 2009-11-19T11:04:13Z + +[Term] +id: GO:0071163 +name: DNA replication preinitiation complex assembly +namespace: biological_process +alt_id: GO:1902293 +alt_id: GO:1902316 +def: "The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity." [GOC:mah, PMID:28209641] +synonym: "DNA replication preinitiation complex formation" EXACT [GOC:mah] +synonym: "pre-IC complex assembly" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: mah +creation_date: 2009-11-19T11:13:41Z + +[Term] +id: GO:0071164 +name: RNA trimethylguanosine synthase activity +namespace: molecular_function +def: "Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine." [GOC:BHF, PMID:11983179, PMID:18775984] +synonym: "cap hypermethylase activity" EXACT [PMID:11983179] +synonym: "small nuclear RNA methyltransferase activity" RELATED [GOC:rl] +synonym: "snRNA methyltransferase activity" RELATED [GOC:rl] +is_a: GO:0008173 ! RNA methyltransferase activity +relationship: part_of GO:0036261 ! 7-methylguanosine cap hypermethylation +created_by: mah +creation_date: 2009-11-19T03:23:20Z + +[Term] +id: GO:0071165 +name: GINS complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks." [GOC:mah, PMID:16990792] +is_a: GO:0071163 ! DNA replication preinitiation complex assembly +created_by: mah +creation_date: 2009-11-19T03:37:20Z + +[Term] +id: GO:0071166 +name: ribonucleoprotein complex localization +namespace: biological_process +def: "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." [GOC:mah] +synonym: "cellular ribonucleoprotein complex localization" EXACT [GOC:mah] +synonym: "establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex localisation" EXACT [GOC:mah] +synonym: "RNP localization" EXACT [GOC:mah] +is_a: GO:0051641 ! cellular localization +created_by: mah +creation_date: 2009-11-19T04:46:05Z + +[Term] +id: GO:0071167 +name: obsolete ribonucleoprotein complex import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus." [GOC:BHF, GOC:mah] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "ribonucleoprotein complex import into cell nucleus" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex nucleus import" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex targeting to nucleus" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex transport from cytoplasm to nucleus" EXACT [GOC:mah] +synonym: "ribonucleoprotein import into nucleus" EXACT [GOC:rl] +synonym: "RNP import into nucleus" EXACT [GOC:mah] +is_obsolete: true +consider: GO:0006606 +created_by: mah +creation_date: 2009-11-19T04:48:42Z + +[Term] +id: GO:0071168 +name: protein localization to chromatin +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah] +synonym: "protein localisation to chromatin" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome +created_by: mah +creation_date: 2009-11-20T11:51:20Z + +[Term] +id: GO:0071169 +name: establishment of protein localization to chromatin +namespace: biological_process +def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah] +synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah] +is_a: GO:0070199 ! establishment of protein localization to chromosome +is_a: GO:0071168 ! protein localization to chromatin +created_by: mah +creation_date: 2009-11-20T11:52:43Z + +[Term] +id: GO:0071170 +name: site-specific DNA replication termination +namespace: biological_process +def: "A DNA replication termination process that takes place at a specific termination site." [GOC:mah, PMID:12009298, PMID:18723894] +comment: See also the biological process term 'replication fork arrest ; GO:0043111' and its children. +is_a: GO:0006274 ! DNA replication termination +created_by: mah +creation_date: 2009-11-20T01:07:30Z + +[Term] +id: GO:0071171 +name: site-specific DNA replication termination at RTS1 barrier +namespace: biological_process +def: "A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching." [GOC:vw, PMID:12009298, PMID:18723894] +is_a: GO:0071170 ! site-specific DNA replication termination +relationship: part_of GO:0071516 ! establishment of imprinting at mating-type locus +created_by: mah +creation_date: 2009-11-20T01:24:41Z + +[Term] +id: GO:0071172 +name: dihydromonapterin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+." [GOC:imk, PMID:19897652] +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor +created_by: mah +creation_date: 2009-11-23T11:10:17Z + +[Term] +id: GO:0071173 +name: spindle assembly checkpoint +namespace: biological_process +def: "A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mah] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic). +subset: gocheck_do_not_manually_annotate +synonym: "SAC" BROAD [GOC:mah] +is_a: GO:0031577 ! spindle checkpoint +created_by: mah +creation_date: 2009-11-23T12:36:57Z + +[Term] +id: GO:0071174 +name: mitotic spindle checkpoint +namespace: biological_process +def: "A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form." [GOC:mtg_cell_cycle] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent). +subset: gocheck_do_not_manually_annotate +synonym: "mitotic cell cycle spindle checkpoint" EXACT [] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:0031577 ! spindle checkpoint +intersection_of: GO:0031577 ! spindle checkpoint +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: mah +creation_date: 2009-11-23T12:41:36Z + +[Term] +id: GO:0071175 +name: MAML2-RBP-Jkappa-ICN1 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML2-RBP-Jkappa-Notch1 complex" EXACT [CORUM:1949] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:36:28Z + +[Term] +id: GO:0071176 +name: MAML2-RBP-Jkappa-ICN2 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML2-RBP-Jkappa-Notch2 complex" EXACT [CORUM:3217] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:42:24Z + +[Term] +id: GO:0071177 +name: MAML2-RBP-Jkappa-ICN3 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML2-RBP-Jkappa-Notch3 complex" EXACT [CORUM:3218] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:48:56Z + +[Term] +id: GO:0071178 +name: MAML2-RBP-Jkappa-ICN4 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML2-RBP-Jkappa-Notch4 complex" EXACT [CORUM:3219] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:49:21Z + +[Term] +id: GO:0071179 +name: MAML3-RBP-Jkappa-ICN1 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML3-RBP-Jkappa-Notch1 complex" EXACT [CORUM:3220] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:50:39Z + +[Term] +id: GO:0071180 +name: MAML3-RBP-Jkappa-ICN2 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML3-RBP-Jkappa-Notch2 complex" EXACT [CORUM:3221] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:51:29Z + +[Term] +id: GO:0071181 +name: MAML3-RBP-Jkappa-ICN3 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML3-RBP-Jkappa-Notch3 complex" EXACT [CORUM:3222] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:52:05Z + +[Term] +id: GO:0071182 +name: MAML3-RBP-Jkappa-ICN4 complex +namespace: cellular_component +def: "A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling." [PMID:12370315] +synonym: "MAML3-RBP-Jkappa-Notch4 complex" EXACT [CORUM:3223] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2009-11-23T02:52:35Z + +[Term] +id: GO:0071183 +name: protocadherin-alpha-protocadherin-gamma complex +namespace: cellular_component +def: "A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: mah +creation_date: 2009-11-23T04:10:30Z + +[Term] +id: GO:0071184 +name: protocadherin-alpha-v4-protocadherin-gamma-a1 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdhga1-Pcdha4 complex" NARROW [CORUM:1014] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:11:47Z + +[Term] +id: GO:0071185 +name: protocadherin-alpha-v4-protocadherin-gamma-a3 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdhga1-Pcdhga3 complex" NARROW [CORUM:1016] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:16:47Z + +[Term] +id: GO:0071186 +name: protocadherin-alpha-v4-protocadherin-gamma-b2 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdhga1-Pcdhgb2 complex" NARROW [CORUM:1015] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:21:33Z + +[Term] +id: GO:0071187 +name: protocadherin-alpha-v4-protocadherin-gamma-b4 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdhga1-Pcdhgb4 complex" NARROW [CORUM:1017] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:22:08Z + +[Term] +id: GO:0071188 +name: protocadherin-alpha-v7-protocadherin-gamma-a1 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdha7-Pcdhga1 complex" NARROW [CORUM:1021] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:23:25Z + +[Term] +id: GO:0071189 +name: protocadherin-alpha-v7-protocadherin-gamma-a3 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdha7-Pcdhga3 complex" NARROW [CORUM:1019] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:24:28Z + +[Term] +id: GO:0071190 +name: protocadherin-alpha-v7-protocadherin-gamma-b2 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdha7-Pcdhgb4 complex" NARROW [CORUM:1018] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:30:12Z + +[Term] +id: GO:0071191 +name: protocadherin-alpha-v7-protocadherin-gamma-b4 complex +namespace: cellular_component +def: "A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane." [PMID:15347688] +synonym: "Pcdha7-Pcdhgb2 complex" NARROW [CORUM:1020] +is_a: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex +created_by: mah +creation_date: 2009-11-23T04:30:51Z + +[Term] +id: GO:0071192 +name: Kv4.2-KChIP1 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2." [PMID:15356203] +xref: CORUM:606 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T04:51:42Z + +[Term] +id: GO:0071193 +name: Kv4.2-KChIP2 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2." [PMID:15356203] +xref: CORUM:607 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T04:58:09Z + +[Term] +id: GO:0071194 +name: Kv4.2-KChIP3 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2." [PMID:15356203] +xref: CORUM:608 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T04:58:41Z + +[Term] +id: GO:0071195 +name: Kv4.2-KChIP4 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2." [PMID:15356203] +xref: CORUM:3090 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T04:59:06Z + +[Term] +id: GO:0071196 +name: Kv4.3-KChIP1 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3." [PMID:15356203] +xref: CORUM:3091 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T04:59:38Z + +[Term] +id: GO:0071197 +name: Kv4.2-Kv4.3 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3." [PMID:15356203] +xref: CORUM:609 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:00:33Z + +[Term] +id: GO:0071198 +name: Kv4.1-DPP6 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1." [PMID:15911355] +synonym: "Kv4.1-DPPX channel complex" EXACT [PMID:15911355] +xref: CORUM:600 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:14:37Z + +[Term] +id: GO:0071199 +name: Kv4.1-DPP10 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1." [PMID:15911355] +synonym: "Kv4.1-DPPY channel complex" EXACT [PMID:15911355] +xref: CORUM:601 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:17:50Z + +[Term] +id: GO:0071200 +name: Kv4.2-DPP6 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2." [PMID:12575952, PMID:15911355] +synonym: "Kv4.2-DPPX channel complex" EXACT [PMID:15911355] +xref: CORUM:603 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:18:31Z + +[Term] +id: GO:0071201 +name: Kv4.3-DPP6 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3." [PMID:12575952, PMID:15911355] +synonym: "Kv4.3-DPPX channel complex" EXACT [PMID:15911355] +xref: CORUM:599 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:20:54Z + +[Term] +id: GO:0071202 +name: Kv4.3-DPP10 channel complex +namespace: cellular_component +def: "A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3." [PMID:15911355] +synonym: "Kv4.3-DPPY channel complex" EXACT [PMID:15911355] +xref: CORUM:598 +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: mah +creation_date: 2009-11-23T05:21:37Z + +[Term] +id: GO:0071203 +name: WASH complex +namespace: cellular_component +def: "A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53." [GOC:sp, PMID:19922875] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-11-25T11:01:33Z + +[Term] +id: GO:0071204 +name: histone pre-mRNA 3'end processing complex +namespace: cellular_component +def: "A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1." [GOC:mah, PMID:19470752] +synonym: "histone 3'end pre-mRNA complex" EXACT [GOC:mah] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2009-11-25T11:11:02Z + +[Term] +id: GO:0071205 +name: protein localization to juxtaparanode region of axon +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon." [GOC:BHF, GOC:mah] +synonym: "protein localisation to juxtaparanode region of axon" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +is_a: GO:0099612 ! protein localization to axon +created_by: mah +creation_date: 2009-11-25T01:13:55Z + +[Term] +id: GO:0071206 +name: establishment of protein localization to juxtaparanode region of axon +namespace: biological_process +def: "The directed movement of a protein to the juxtaparanode region of an axon." [GOC:BHF, GOC:mah] +synonym: "establishment of protein localisation to juxtaparanode region of axon" EXACT [GOC:mah] +is_a: GO:0045184 ! establishment of protein localization +is_a: GO:0071205 ! protein localization to juxtaparanode region of axon +created_by: mah +creation_date: 2009-11-25T01:15:23Z + +[Term] +id: GO:0071207 +name: histone pre-mRNA stem-loop binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs." [PMID:19470752] +is_a: GO:0036002 ! pre-mRNA binding +created_by: mah +creation_date: 2009-11-25T01:25:15Z + +[Term] +id: GO:0071208 +name: histone pre-mRNA DCP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing." [PMID:19470752] +is_a: GO:0003723 ! RNA binding +created_by: mah +creation_date: 2009-11-25T01:41:35Z + +[Term] +id: GO:0071209 +name: U7 snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA)." [GOC:mah, PMID:12975319] +comment: Note that this term may be useful for annotating other small nuclear RNAs (snRNAs). +is_a: GO:0017069 ! snRNA binding +created_by: mah +creation_date: 2009-11-25T01:46:50Z + +[Term] +id: GO:0071210 +name: protein insertion into membrane raft +namespace: biological_process +def: "The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes." [GOC:mah] +synonym: "establishment of protein localization to membrane raft" BROAD [GOC:mah, GOC:vw] +is_a: GO:0051205 ! protein insertion into membrane +is_a: GO:1903044 ! protein localization to membrane raft +relationship: part_of GO:0031579 ! membrane raft organization +created_by: mah +creation_date: 2009-11-25T02:11:46Z + +[Term] +id: GO:0071211 +name: protein targeting to vacuole involved in autophagy +namespace: biological_process +def: "The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm." [GOC:mah] +synonym: "protein targeting to autophagosome" RELATED [GOC:pad] +is_a: GO:0006623 ! protein targeting to vacuole +intersection_of: GO:0006623 ! protein targeting to vacuole +intersection_of: part_of GO:0006914 ! autophagy +relationship: part_of GO:0006914 ! autophagy +created_by: mah +creation_date: 2009-11-25T02:25:27Z + +[Term] +id: GO:0071212 +name: subsynaptic reticulum +namespace: cellular_component +def: "An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane." [PMID:1460464, PMID:18171947, PMID:19244343, PMID:7946331] +synonym: "SSR" EXACT [PMID:19244343] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0061174 ! type I terminal bouton +created_by: mah +creation_date: 2009-12-01T05:05:21Z + +[Term] +id: GO:0071213 +name: cellular response to 1-aminocyclopropane-1-carboxylic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus." [GOC:mah] +is_a: GO:0009961 ! response to 1-aminocyclopropane-1-carboxylic acid +is_a: GO:0071230 ! cellular response to amino acid stimulus +created_by: mah +creation_date: 2009-12-03T12:10:11Z + +[Term] +id: GO:0071214 +name: cellular response to abiotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "cellular response to abiotic stress" NARROW [GOC:mah] +is_a: GO:0009628 ! response to abiotic stimulus +is_a: GO:0104004 ! cellular response to environmental stimulus +created_by: mah +creation_date: 2009-12-03T01:02:11Z + +[Term] +id: GO:0071215 +name: cellular response to abscisic acid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus." [GOC:mah] +is_a: GO:0009737 ! response to abscisic acid +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2009-12-03T01:04:18Z + +[Term] +id: GO:0071216 +name: cellular response to biotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "cellular response to biotic stress" NARROW [GOC:mah] +is_a: GO:0009607 ! response to biotic stimulus +is_a: GO:0051716 ! cellular response to stimulus +created_by: mah +creation_date: 2009-12-03T01:09:08Z + +[Term] +id: GO:0071217 +name: cellular response to external biotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:mah] +is_a: GO:0043207 ! response to external biotic stimulus +is_a: GO:0071216 ! cellular response to biotic stimulus +is_a: GO:0071496 ! cellular response to external stimulus +created_by: mah +creation_date: 2009-12-03T01:14:27Z + +[Term] +id: GO:0071218 +name: cellular response to misfolded protein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus." [GOC:mah] +is_a: GO:0035967 ! cellular response to topologically incorrect protein +is_a: GO:0051788 ! response to misfolded protein +created_by: mah +creation_date: 2009-12-03T01:17:46Z + +[Term] +id: GO:0071219 +name: cellular response to molecule of bacterial origin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin." [GOC:mah] +synonym: "cellular response to bacteria associated molecule" EXACT [GOC:mah] +synonym: "cellular response to bacterial associated molecule" EXACT [GOC:mah] +synonym: "cellular response to bacterium associated molecule" EXACT [GOC:mah] +is_a: GO:0002237 ! response to molecule of bacterial origin +is_a: GO:0071216 ! cellular response to biotic stimulus +created_by: mah +creation_date: 2009-12-03T01:22:00Z + +[Term] +id: GO:0071220 +name: cellular response to bacterial lipoprotein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus." [GOC:mah] +is_a: GO:0032493 ! response to bacterial lipoprotein +is_a: GO:0071219 ! cellular response to molecule of bacterial origin +created_by: mah +creation_date: 2009-12-03T01:26:36Z + +[Term] +id: GO:0071221 +name: cellular response to bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus." [GOC:mah] +is_a: GO:0070339 ! response to bacterial lipopeptide +is_a: GO:0071220 ! cellular response to bacterial lipoprotein +created_by: mah +creation_date: 2009-12-03T01:28:03Z + +[Term] +id: GO:0071222 +name: cellular response to lipopolysaccharide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." [GOC:mah] +synonym: "cellular response to endotoxin" BROAD [GOC:mah, GOC:sl] +synonym: "cellular response to LPS" EXACT [GOC:mah] +is_a: GO:0032496 ! response to lipopolysaccharide +is_a: GO:0071219 ! cellular response to molecule of bacterial origin +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T01:29:29Z + +[Term] +id: GO:0071223 +name: cellular response to lipoteichoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:mah] +synonym: "cellular response to LTA" EXACT [GOC:mah] +is_a: GO:0070391 ! response to lipoteichoic acid +is_a: GO:0071219 ! cellular response to molecule of bacterial origin +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T01:31:00Z + +[Term] +id: GO:0071224 +name: cellular response to peptidoglycan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule." [GOC:mah] +is_a: GO:0032494 ! response to peptidoglycan +is_a: GO:0071219 ! cellular response to molecule of bacterial origin +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T01:36:38Z + +[Term] +id: GO:0071225 +name: cellular response to muramyl dipeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan." [GOC:mah] +is_a: GO:0032495 ! response to muramyl dipeptide +is_a: GO:0035690 ! cellular response to drug +is_a: GO:1901653 ! cellular response to peptide +created_by: mah +creation_date: 2009-12-03T01:41:23Z + +[Term] +id: GO:0071226 +name: cellular response to molecule of fungal origin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide." [GOC:mah] +synonym: "cellular response to fungus associated molecule" EXACT [GOC:mah] +is_a: GO:0002238 ! response to molecule of fungal origin +is_a: GO:0071216 ! cellular response to biotic stimulus +created_by: mah +creation_date: 2009-12-03T01:50:01Z + +[Term] +id: GO:0071227 +name: cellular response to molecule of oomycetes origin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin." [GOC:mah] +synonym: "cellular response to oomycetes associated molecule" EXACT [GOC:mah] +is_a: GO:0002240 ! response to molecule of oomycetes origin +is_a: GO:0071216 ! cellular response to biotic stimulus +is_a: GO:0071310 ! cellular response to organic substance +relationship: part_of GO:0009620 ! response to fungus +created_by: mah +creation_date: 2009-12-03T01:55:09Z + +[Term] +id: GO:0071228 +name: cellular response to tumor cell +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell." [GOC:mah] +is_a: GO:0002347 ! response to tumor cell +is_a: GO:0071216 ! cellular response to biotic stimulus +created_by: mah +creation_date: 2009-12-03T02:04:43Z + +[Term] +id: GO:0071229 +name: cellular response to acid chemical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:mah, Wikipedia:Acid] +comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead. +subset: gocheck_do_not_manually_annotate +synonym: "cellular response to acid" BROAD [] +synonym: "cellular response to acid anion" RELATED [] +synonym: "cellular response to oxoanion" RELATED [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-03T02:07:23Z + +[Term] +id: GO:0071230 +name: cellular response to amino acid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:mah] +synonym: "cellular response to amino acid" EXACT [GOC:mah] +is_a: GO:0043200 ! response to amino acid +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:08:11Z + +[Term] +id: GO:0071231 +name: cellular response to folic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus." [GOC:mah] +synonym: "response to folate" EXACT [GOC:mah] +synonym: "response to vitamin B9" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0051593 ! response to folic acid +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:08:32Z + +[Term] +id: GO:0071232 +name: cellular response to histidine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus." [GOC:mah] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0080052 ! response to histidine +created_by: mah +creation_date: 2009-12-03T02:09:15Z + +[Term] +id: GO:0071233 +name: cellular response to leucine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus." [GOC:mah] +is_a: GO:0043201 ! response to leucine +is_a: GO:0071230 ! cellular response to amino acid stimulus +created_by: mah +creation_date: 2009-12-03T02:09:26Z + +[Term] +id: GO:0071234 +name: cellular response to phenylalanine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus." [GOC:mah] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0080053 ! response to phenylalanine +created_by: mah +creation_date: 2009-12-03T02:09:36Z + +[Term] +id: GO:0071235 +name: cellular response to proline +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus." [GOC:mah] +is_a: GO:0010238 ! response to proline +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-03T02:09:45Z + +[Term] +id: GO:0071236 +name: cellular response to antibiotic +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms." [GOC:mah] +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-03T02:23:49Z + +[Term] +id: GO:0071237 +name: cellular response to bacteriocin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation." [GOC:mah] +is_a: GO:0046678 ! response to bacteriocin +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:1901653 ! cellular response to peptide +created_by: mah +creation_date: 2009-12-03T02:25:43Z + +[Term] +id: GO:0071238 +name: cellular response to brefeldin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus." [GOC:mah] +is_a: GO:0031001 ! response to brefeldin A +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:25:52Z + +[Term] +id: GO:0071239 +name: cellular response to streptomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0046679 ! response to streptomycin +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:25:59Z + +[Term] +id: GO:0071240 +name: cellular response to food +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." [GOC:mah] +is_a: GO:0032094 ! response to food +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-03T02:28:35Z + +[Term] +id: GO:0071241 +name: cellular response to inorganic substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:mah] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-03T02:35:49Z + +[Term] +id: GO:0071242 +name: cellular response to ammonium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus." [GOC:mah] +is_a: GO:0060359 ! response to ammonium ion +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: mah +creation_date: 2009-12-03T02:39:40Z + +[Term] +id: GO:0071243 +name: cellular response to arsenic-containing substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:mah] +synonym: "cellular response to arsenic" EXACT [] +is_a: GO:0046685 ! response to arsenic-containing substance +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-03T02:41:05Z + +[Term] +id: GO:0071244 +name: cellular response to carbon dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus." [GOC:mah] +is_a: GO:0010037 ! response to carbon dioxide +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:41:21Z + +[Term] +id: GO:0071245 +name: cellular response to carbon monoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus." [GOC:mah] +is_a: GO:0034465 ! response to carbon monoxide +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:44:43Z + +[Term] +id: GO:0071246 +name: cellular response to chlorate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus." [GOC:mah] +is_a: GO:0010157 ! response to chlorate +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:45:36Z + +[Term] +id: GO:0071247 +name: cellular response to chromate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus." [GOC:mah] +is_a: GO:0046687 ! response to chromate +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T02:46:01Z + +[Term] +id: GO:0071248 +name: cellular response to metal ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:mah] +synonym: "cellular response to heavy metal" NARROW [GOC:mah] +synonym: "cellular response to metal" EXACT [GOC:mah] +is_a: GO:0010038 ! response to metal ion +is_a: GO:0071241 ! cellular response to inorganic substance +created_by: mah +creation_date: 2009-12-03T02:46:31Z + +[Term] +id: GO:0071249 +name: cellular response to nitrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus." [GOC:mah] +is_a: GO:0010167 ! response to nitrate +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902170 ! cellular response to reactive nitrogen species +created_by: mah +creation_date: 2009-12-03T03:02:06Z + +[Term] +id: GO:0071250 +name: cellular response to nitrite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus." [GOC:mah] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0080033 ! response to nitrite +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902170 ! cellular response to reactive nitrogen species +created_by: mah +creation_date: 2009-12-03T03:03:49Z + +[Term] +id: GO:0071251 +name: cellular response to silicon dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus." [GOC:mah] +synonym: "cellular response to silica" EXACT [GOC:mah] +synonym: "cellular response to silox" EXACT [GOC:mah] +is_a: GO:0034021 ! response to silicon dioxide +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T03:09:41Z + +[Term] +id: GO:0071252 +name: cellular response to sulfur dioxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus." [GOC:mah] +is_a: GO:0010477 ! response to sulfur dioxide +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-03T03:10:16Z + +[Term] +id: GO:0071253 +name: connexin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions." [GOC:mah, PMID:19864490] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: mah +creation_date: 2009-12-04T10:07:54Z + +[Term] +id: GO:0071254 +name: cytoplasmic U snRNP body +namespace: cellular_component +def: "A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies." [GOC:sart, PMID:17595295] +synonym: "U body" EXACT [GOC:sart, PMID:17595295] +synonym: "U-body" EXACT [GOC:mah] +is_a: GO:1990904 ! ribonucleoprotein complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2009-12-04T10:31:29Z + +[Term] +id: GO:0071255 +name: Cvt vesicle assembly +namespace: biological_process +def: "A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI)." [GOC:rb, PMID:10966461, PMID:11085977] +synonym: "Cvt vesicle biosynthesis" RELATED [GOC:mah] +synonym: "Cvt vesicle formation" EXACT [GOC:mah] +synonym: "cytoplasm to vacuole targeting vesicle assembly" EXACT [] +synonym: "cytoplasm-to-vacuole targetin vesicle assembly" EXACT [] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0032258 ! cytoplasm to vacuole transport by the Cvt pathway +created_by: mah +creation_date: 2009-12-04T10:39:50Z + +[Term] +id: GO:0071256 +name: translocon complex +namespace: cellular_component +alt_id: GO:0031206 +def: "A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins." [GOC:mah, PMID:10611978, PMID:18166647, PMID:8612571] +subset: goslim_pir +synonym: "Sec complex-associated translocon complex" NARROW [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030867 ! rough endoplasmic reticulum membrane +created_by: mah +creation_date: 2009-12-08T02:08:03Z + +[Term] +id: GO:0071257 +name: cellular response to electrical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:mah] +synonym: "cellular response to electricity" RELATED [GOC:mah] +is_a: GO:0051602 ! response to electrical stimulus +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-04T03:27:03Z + +[Term] +id: GO:0071258 +name: cellular response to gravity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus." [GOC:mah] +synonym: "cellular response to gravitational stimulus" EXACT [GOC:mah] +is_a: GO:0009629 ! response to gravity +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-04T03:31:36Z + +[Term] +id: GO:0071259 +name: cellular response to magnetism +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus." [GOC:mah] +synonym: "cellular response to magnetic stimulus" EXACT [GOC:mah] +is_a: GO:0071000 ! response to magnetism +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-04T03:54:53Z + +[Term] +id: GO:0071260 +name: cellular response to mechanical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus." [GOC:mah] +synonym: "cellular mechanical stimulus response" EXACT [GOC:mah] +is_a: GO:0009612 ! response to mechanical stimulus +is_a: GO:0071214 ! cellular response to abiotic stimulus +is_a: GO:0071496 ! cellular response to external stimulus +created_by: mah +creation_date: 2009-12-04T03:55:44Z + +[Term] +id: GO:0071261 +name: Ssh1 translocon complex +namespace: cellular_component +def: "A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences." [GOC:mah, PMID:12134063, PMID:8612571] +synonym: "Ssh1p-Sss1p-Sbh2p complex" NARROW [GOC:mah] +is_a: GO:0071256 ! translocon complex +created_by: mah +creation_date: 2009-12-08T02:22:55Z + +[Term] +id: GO:0071262 +name: regulation of translational initiation in response to starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment." [GOC:mah] +synonym: "regulation of translational initiation in response to nutrient starvation" EXACT [GOC:vw] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0043558 ! regulation of translational initiation in response to stress +created_by: mah +creation_date: 2009-12-08T05:31:05Z + +[Term] +id: GO:0071263 +name: negative regulation of translational initiation in response to starvation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment." [GOC:mah] +synonym: "down regulation of translation initiation in response to starvation" EXACT [GOC:mah] +synonym: "down-regulation of translation initiation in response to starvation" EXACT [GOC:mah] +synonym: "downregulation of translation initiation in response to starvation" EXACT [GOC:mah] +synonym: "inhibition of translation initiation in response to starvation" NARROW [GOC:mah] +synonym: "negative regulation of translational initiation in response to nutrient starvation" EXACT [GOC:vw] +is_a: GO:0032057 ! negative regulation of translational initiation in response to stress +is_a: GO:0071262 ! regulation of translational initiation in response to starvation +created_by: mah +creation_date: 2009-12-08T05:33:12Z + +[Term] +id: GO:0071264 +name: positive regulation of translational initiation in response to starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment." [GOC:mah] +synonym: "activation of translation initiation in response to starvation" NARROW [GOC:mah] +synonym: "positive regulation of translational initiation in response to nutrient starvation" EXACT [GOC:mah] +synonym: "stimulation of translation initiation in response to starvation" NARROW [GOC:mah] +synonym: "up regulation of translation initiation in response to starvation" EXACT [GOC:mah] +synonym: "up-regulation of translation initiation in response to starvation" EXACT [GOC:mah] +synonym: "upregulation of translation initiation in response to starvation" EXACT [GOC:mah] +is_a: GO:0032058 ! positive regulation of translational initiation in response to stress +is_a: GO:0071262 ! regulation of translational initiation in response to starvation +created_by: mah +creation_date: 2009-12-08T05:35:45Z + +[Term] +id: GO:0071265 +name: L-methionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid." [GOC:ecd] +synonym: "L-methionine anabolism" EXACT [GOC:mah] +synonym: "L-methionine biosynthesis" EXACT [GOC:mah] +synonym: "L-methionine formation" EXACT [GOC:mah] +synonym: "L-methionine synthesis" EXACT [GOC:mah] +is_a: GO:0009086 ! methionine biosynthetic process +is_a: GO:0017144 ! drug metabolic process +created_by: mah +creation_date: 2009-12-09T04:28:15Z + +[Term] +id: GO:0071266 +name: 'de novo' L-methionine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components." [GOC:ecd] +synonym: "'de novo' L-methionine anabolism" EXACT [GOC:mah] +synonym: "'de novo' L-methionine biosynthesis" EXACT [GOC:mah] +synonym: "'de novo' L-methionine formation" EXACT [GOC:mah] +synonym: "'de novo' L-methionine synthesis" EXACT [GOC:mah] +is_a: GO:0071265 ! L-methionine biosynthetic process +created_by: mah +creation_date: 2009-12-09T04:34:41Z + +[Term] +id: GO:0071267 +name: L-methionine salvage +namespace: biological_process +def: "Any process that generates L-methionine from derivatives of it, without de novo synthesis." [GOC:ecd] +is_a: GO:0043102 ! amino acid salvage +is_a: GO:0071265 ! L-methionine biosynthetic process +created_by: mah +creation_date: 2009-12-09T04:36:49Z + +[Term] +id: GO:0071268 +name: homocysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid." [GOC:ecd, GOC:mah] +synonym: "homocysteine anabolism" EXACT [GOC:mah] +synonym: "homocysteine biosynthesis" EXACT [GOC:mah] +synonym: "homocysteine formation" EXACT [GOC:mah] +synonym: "homocysteine synthesis" EXACT [GOC:mah] +is_a: GO:0000097 ! sulfur amino acid biosynthetic process +is_a: GO:0050667 ! homocysteine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +created_by: mah +creation_date: 2009-12-09T05:32:48Z + +[Term] +id: GO:0071269 +name: L-homocysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid." [GOC:ecd, GOC:mah] +synonym: "L-homocysteine anabolism" EXACT [GOC:mah] +synonym: "L-homocysteine biosynthesis" EXACT [GOC:mah] +synonym: "L-homocysteine formation" EXACT [GOC:mah] +synonym: "L-homocysteine synthesis" EXACT [GOC:mah] +is_a: GO:0009070 ! serine family amino acid biosynthetic process +is_a: GO:0071268 ! homocysteine biosynthetic process +created_by: mah +creation_date: 2009-12-09T05:36:37Z + +[Term] +id: GO:0071270 +name: 1-butanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O." [GOC:ecd, GOC:mah] +synonym: "1-butanol metabolism" EXACT [GOC:mah] +synonym: "butan-1-ol metabolic process" EXACT [CHEBI:28885] +synonym: "butanol metabolic process" BROAD [GOC:mah] +is_a: GO:0034308 ! primary alcohol metabolic process +created_by: mah +creation_date: 2009-12-10T10:23:11Z + +[Term] +id: GO:0071271 +name: 1-butanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O." [GOC:ecd, GOC:mah] +synonym: "1-butanol anabolism" EXACT [GOC:mah] +synonym: "1-butanol biosynthesis" EXACT [GOC:mah] +synonym: "1-butanol formation" EXACT [GOC:mah] +synonym: "1-butanol synthesis" EXACT [GOC:mah] +synonym: "butan-1-ol biosynthetic process" EXACT [CHEBI:28885] +synonym: "butanol biosynthetic process" BROAD [GOC:mah] +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0071270 ! 1-butanol metabolic process +created_by: mah +creation_date: 2009-12-10T10:27:24Z + +[Term] +id: GO:0071272 +name: morphine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum." [GOC:mah] +synonym: "morphine metabolism" EXACT [GOC:mah] +xref: Wikipedia:Morphine +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: mah +creation_date: 2009-12-10T11:11:51Z + +[Term] +id: GO:0071273 +name: morphine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum." [GOC:ecd, GOC:mah] +synonym: "morphine breakdown" EXACT [GOC:mah] +synonym: "morphine catabolism" EXACT [GOC:mah] +synonym: "morphine degradation" EXACT [GOC:mah] +xref: UniPathway:Q02198 +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0071272 ! morphine metabolic process +is_a: GO:0071274 ! isoquinoline alkaloid catabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +created_by: mah +creation_date: 2009-12-10T11:16:28Z + +[Term] +id: GO:0071274 +name: isoquinoline alkaloid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin." [GOC:mah, http://www.life.uiuc.edu/ib/425/lecture32.html] +synonym: "ipecac alkaloid catabolism" RELATED [GOC:mah] +synonym: "isoquinoline alkaloid breakdown" EXACT [GOC:mah] +synonym: "isoquinoline alkaloid catabolism" EXACT [GOC:mah] +synonym: "isoquinoline alkaloid degradation" EXACT [GOC:mah] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: mah +creation_date: 2009-12-10T11:17:49Z + +[Term] +id: GO:0071275 +name: cellular response to aluminum ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus." [GOC:mah] +synonym: "cellular response to aluminium ion" EXACT [GOC:mah] +synonym: "cellular response to aluminum" EXACT [GOC:mah] +is_a: GO:0010044 ! response to aluminum ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:52:20Z + +[Term] +id: GO:0071276 +name: cellular response to cadmium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus." [GOC:mah] +synonym: "cellular response to cadmium" EXACT [GOC:mah] +is_a: GO:0046686 ! response to cadmium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:54:49Z + +[Term] +id: GO:0071277 +name: cellular response to calcium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." [GOC:mah] +synonym: "cellular response to Ca2+ ion" EXACT [GOC:mah] +is_a: GO:0051592 ! response to calcium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:55:01Z + +[Term] +id: GO:0071278 +name: cellular response to cesium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus." [GOC:mah] +synonym: "cellular response to cesium" EXACT [GOC:mah] +is_a: GO:0010164 ! response to cesium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:55:44Z + +[Term] +id: GO:0071279 +name: cellular response to cobalt ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus." [GOC:mah] +is_a: GO:0032025 ! response to cobalt ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:55:55Z + +[Term] +id: GO:0071280 +name: cellular response to copper ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus." [GOC:mah] +synonym: "cellular response to copper" EXACT [GOC:mah] +is_a: GO:0046688 ! response to copper ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:57:03Z + +[Term] +id: GO:0071281 +name: cellular response to iron ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus." [GOC:mah] +synonym: "cellular response to iron" EXACT [GOC:mah] +is_a: GO:0010039 ! response to iron ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T03:57:22Z + +[Term] +id: GO:0071282 +name: cellular response to iron(II) ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus." [GOC:mah] +synonym: "cellular response to iron(II)" EXACT [GOC:mah] +is_a: GO:0010040 ! response to iron(II) ion +is_a: GO:0071281 ! cellular response to iron ion +created_by: mah +creation_date: 2009-12-10T03:57:49Z + +[Term] +id: GO:0071283 +name: cellular response to iron(III) ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus." [GOC:mah] +synonym: "cellular response to iron(III)" EXACT [GOC:mah] +is_a: GO:0010041 ! response to iron(III) ion +is_a: GO:0071281 ! cellular response to iron ion +created_by: mah +creation_date: 2009-12-10T03:58:00Z + +[Term] +id: GO:0071284 +name: cellular response to lead ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus." [GOC:mah] +is_a: GO:0010288 ! response to lead ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:00:41Z + +[Term] +id: GO:0071285 +name: cellular response to lithium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus." [GOC:mah] +is_a: GO:0010226 ! response to lithium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:04:13Z + +[Term] +id: GO:0071286 +name: cellular response to magnesium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus." [GOC:mah] +is_a: GO:0032026 ! response to magnesium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:05:50Z + +[Term] +id: GO:0071287 +name: cellular response to manganese ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus." [GOC:mah] +synonym: "cellular response to manganese" EXACT [GOC:mah] +is_a: GO:0010042 ! response to manganese ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:06:18Z + +[Term] +id: GO:0071288 +name: cellular response to mercury ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus." [GOC:mah] +synonym: "cellular response to mercuric ion" EXACT [GOC:mah] +synonym: "cellular response to mercury" EXACT [GOC:mah] +is_a: GO:0046689 ! response to mercury ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:06:37Z + +[Term] +id: GO:0071289 +name: cellular response to nickel ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus." [GOC:mah] +synonym: "cellular response to nickel" EXACT [GOC:mah] +is_a: GO:0010045 ! response to nickel cation +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:07:31Z + +[Term] +id: GO:0071290 +name: cellular response to platinum ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus." [GOC:mah] +synonym: "cellular response to platinum" EXACT [GOC:mah] +is_a: GO:0070541 ! response to platinum ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:08:06Z + +[Term] +id: GO:0071291 +name: cellular response to selenium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion." [GOC:mah] +is_a: GO:0010269 ! response to selenium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:15:52Z + +[Term] +id: GO:0071292 +name: cellular response to silver ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus." [GOC:mah] +is_a: GO:0010272 ! response to silver ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:16:30Z + +[Term] +id: GO:0071293 +name: cellular response to tellurium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus." [GOC:mah] +synonym: "cellular response to tellurium" EXACT [GOC:mah] +is_a: GO:0046690 ! response to tellurium ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:16:52Z + +[Term] +id: GO:0071294 +name: cellular response to zinc ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus." [GOC:mah] +synonym: "cellular response to zinc" EXACT [GOC:mah] +is_a: GO:0010043 ! response to zinc ion +is_a: GO:0071248 ! cellular response to metal ion +created_by: mah +creation_date: 2009-12-10T04:17:10Z + +[Term] +id: GO:0071295 +name: cellular response to vitamin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus." [GOC:mah] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0033273 ! response to vitamin +created_by: mah +creation_date: 2009-12-10T04:27:24Z + +[Term] +id: GO:0071296 +name: cellular response to biotin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus." [GOC:mah] +synonym: "cellular response to Bios IIB" EXACT [GOC:sl] +synonym: "cellular response to coenzyme R" EXACT [GOC:sl] +synonym: "cellular response to vitamin B7" EXACT [GOC:sl] +synonym: "cellular response to vitamin H" EXACT [GOC:sl] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0070781 ! response to biotin +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:28:22Z + +[Term] +id: GO:0071297 +name: cellular response to cobalamin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus." [GOC:mah] +synonym: "cellular response to vitamin B12" EXACT [GOC:mah] +is_a: GO:0033590 ! response to cobalamin +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-10T04:28:45Z + +[Term] +id: GO:0071298 +name: cellular response to L-ascorbic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus." [GOC:mah] +synonym: "cellular response to ascorbic acid" BROAD [GOC:mah] +synonym: "cellular response to L-ascorbate" EXACT [GOC:mah] +synonym: "cellular response to vitamin C" EXACT [GOC:mah] +is_a: GO:0033591 ! response to L-ascorbic acid +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071326 ! cellular response to monosaccharide stimulus +created_by: mah +creation_date: 2009-12-10T04:29:19Z + +[Term] +id: GO:0071299 +name: cellular response to vitamin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus." [GOC:mah] +synonym: "cellular response to retinol" NARROW [GOC:mah] +is_a: GO:0033189 ! response to vitamin A +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071396 ! cellular response to lipid +created_by: mah +creation_date: 2009-12-10T04:29:30Z + +[Term] +id: GO:0071300 +name: cellular response to retinoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus." [GOC:mah] +synonym: "cellular response to vitamin A acid" EXACT [GOC:mah] +is_a: GO:0032526 ! response to retinoic acid +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:30:34Z + +[Term] +id: GO:0071301 +name: cellular response to vitamin B1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus." [GOC:mah] +synonym: "cellular response to thiamin" EXACT [GOC:mah] +synonym: "cellular response to thiamine" EXACT [GOC:mah] +is_a: GO:0010266 ! response to vitamin B1 +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-10T04:32:09Z + +[Term] +id: GO:0071302 +name: cellular response to vitamin B2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus." [GOC:mah] +synonym: "cellular response to riboflavin" EXACT [GOC:mah] +is_a: GO:0033274 ! response to vitamin B2 +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-10T04:34:52Z + +[Term] +id: GO:0071303 +name: cellular response to vitamin B3 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus." [GOC:mah] +synonym: "cellular response to niacin" NARROW [GOC:mah] +synonym: "cellular response to nicotinamide" NARROW [GOC:mah] +is_a: GO:0033552 ! response to vitamin B3 +is_a: GO:0071295 ! cellular response to vitamin +created_by: mah +creation_date: 2009-12-10T04:35:04Z + +[Term] +id: GO:0071304 +name: cellular response to vitamin B6 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate." [GOC:mah] +is_a: GO:0034516 ! response to vitamin B6 +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-10T04:35:23Z + +[Term] +id: GO:0071305 +name: cellular response to vitamin D +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus." [GOC:mah] +synonym: "cellular response to calciferol" EXACT [GOC:mah] +synonym: "cellular response to cholecalciferol" NARROW [GOC:mah] +synonym: "cellular response to ergocalciferol" NARROW [GOC:mah] +is_a: GO:0033280 ! response to vitamin D +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:35:37Z + +[Term] +id: GO:0071306 +name: cellular response to vitamin E +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus." [GOC:mah] +synonym: "cellular response to DL-alpha-tocopherol acetate" NARROW [GOC:mah] +synonym: "cellular response to DL-alpha-tocopheryl acetate" NARROW [GOC:mah] +synonym: "cellular response to O-Acetyl-alpha-tocopherol" NARROW [GOC:mah] +is_a: GO:0033197 ! response to vitamin E +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:35:58Z + +[Term] +id: GO:0071307 +name: cellular response to vitamin K +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus." [GOC:mah] +is_a: GO:0032571 ! response to vitamin K +is_a: GO:0071295 ! cellular response to vitamin +created_by: mah +creation_date: 2009-12-10T04:36:09Z + +[Term] +id: GO:0071308 +name: cellular response to menaquinone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus." [GOC:mah] +synonym: "cellular response to menatetrenone" EXACT [GOC:mah] +synonym: "cellular response to vitamin K2" EXACT [GOC:mah] +is_a: GO:0032572 ! response to menaquinone +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-10T04:37:08Z + +[Term] +id: GO:0071309 +name: cellular response to phylloquinone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus." [GOC:mah] +synonym: "cellular response to vitamin K1" EXACT [GOC:mah] +is_a: GO:0032573 ! response to phylloquinone +is_a: GO:0071295 ! cellular response to vitamin +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-10T04:37:18Z + +[Term] +id: GO:0071310 +name: cellular response to organic substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:mah] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-10T04:46:04Z + +[Term] +id: GO:0071311 +name: cellular response to acetate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:mah] +is_a: GO:0010034 ! response to acetate +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:48:16Z + +[Term] +id: GO:0071312 +name: cellular response to alkaloid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:mah] +is_a: GO:0043279 ! response to alkaloid +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-10T04:50:58Z + +[Term] +id: GO:0071313 +name: cellular response to caffeine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them." [GOC:mah] +is_a: GO:0031000 ! response to caffeine +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071415 ! cellular response to purine-containing compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +created_by: mah +creation_date: 2009-12-10T04:52:51Z + +[Term] +id: GO:0071314 +name: cellular response to cocaine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0042220 ! response to cocaine +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T04:53:20Z + +[Term] +id: GO:0071315 +name: cellular response to morphine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0043278 ! response to morphine +is_a: GO:0071317 ! cellular response to isoquinoline alkaloid +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +created_by: mah +creation_date: 2009-12-10T04:53:46Z + +[Term] +id: GO:0071316 +name: cellular response to nicotine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus." [GOC:mah] +is_a: GO:0035094 ! response to nicotine +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0097237 ! cellular response to toxic substance +created_by: mah +creation_date: 2009-12-10T05:05:05Z + +[Term] +id: GO:0071317 +name: cellular response to isoquinoline alkaloid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids." [GOC:mah] +is_a: GO:0014072 ! response to isoquinoline alkaloid +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-10T05:06:08Z + +[Term] +id: GO:0071318 +name: cellular response to ATP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus." [GOC:mah] +synonym: "cellular response to adenosine 5'-triphosphate" EXACT [GOC:mah] +synonym: "cellular response to adenosine triphosphate" EXACT [GOC:mah] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0033198 ! response to ATP +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:09:47Z + +[Term] +id: GO:0071319 +name: cellular response to benzoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0080021 ! response to benzoic acid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:10:20Z + +[Term] +id: GO:0071320 +name: cellular response to cAMP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus." [GOC:mah] +synonym: "cellular response to 3',5' cAMP" EXACT [GOC:mah] +synonym: "cellular response to 3',5'-cAMP" EXACT [GOC:mah] +synonym: "cellular response to adenosine 3',5'-cyclophosphate" EXACT [GOC:mah] +synonym: "cellular response to cyclic AMP" EXACT [GOC:mah] +is_a: GO:0051591 ! response to cAMP +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:12:15Z + +[Term] +id: GO:0071321 +name: cellular response to cGMP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus." [GOC:mah] +synonym: "cellular response to 3',5' cGMP" EXACT [GOC:mah] +synonym: "cellular response to 3',5'-cGMP" EXACT [GOC:mah] +synonym: "cellular response to cyclic GMP" EXACT [GOC:mah] +synonym: "cellular response to guanosine 3',5'-cyclophosphate" EXACT [GOC:mah] +is_a: GO:0070305 ! response to cGMP +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:12:58Z + +[Term] +id: GO:0071322 +name: cellular response to carbohydrate stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:mah] +is_a: GO:0009743 ! response to carbohydrate +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:13:33Z + +[Term] +id: GO:0071323 +name: cellular response to chitin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:mah] +is_a: GO:0010200 ! response to chitin +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-10T05:25:54Z + +[Term] +id: GO:0071324 +name: cellular response to disaccharide stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus." [GOC:mah] +is_a: GO:0034285 ! response to disaccharide +is_a: GO:0071322 ! cellular response to carbohydrate stimulus +created_by: mah +creation_date: 2009-12-10T05:26:14Z + +[Term] +id: GO:0071325 +name: cellular response to mannitol stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus." [GOC:mah] +is_a: GO:0010555 ! response to mannitol +is_a: GO:0071322 ! cellular response to carbohydrate stimulus +created_by: mah +creation_date: 2009-12-10T05:27:00Z + +[Term] +id: GO:0071326 +name: cellular response to monosaccharide stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] +is_a: GO:0034284 ! response to monosaccharide +is_a: GO:0071322 ! cellular response to carbohydrate stimulus +created_by: mah +creation_date: 2009-12-10T05:27:18Z + +[Term] +id: GO:0071327 +name: cellular response to trehalose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus." [GOC:mah] +is_a: GO:0010353 ! response to trehalose +is_a: GO:0071324 ! cellular response to disaccharide stimulus +created_by: mah +creation_date: 2009-12-10T05:27:54Z + +[Term] +id: GO:0071328 +name: cellular response to maltose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus." [GOC:mah] +is_a: GO:0034286 ! response to maltose +is_a: GO:0071324 ! cellular response to disaccharide stimulus +created_by: mah +creation_date: 2009-12-10T05:30:45Z + +[Term] +id: GO:0071329 +name: cellular response to sucrose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus." [GOC:mah] +is_a: GO:0009744 ! response to sucrose +is_a: GO:0071324 ! cellular response to disaccharide stimulus +created_by: mah +creation_date: 2009-12-10T05:31:22Z + +[Term] +id: GO:0071330 +name: cellular response to trehalose-6-phosphate stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus." [GOC:mah] +is_a: GO:0071324 ! cellular response to disaccharide stimulus +is_a: GO:0080094 ! response to trehalose-6-phosphate +created_by: mah +creation_date: 2009-12-10T05:32:52Z + +[Term] +id: GO:0071331 +name: cellular response to hexose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:mah] +is_a: GO:0009746 ! response to hexose +is_a: GO:0071326 ! cellular response to monosaccharide stimulus +created_by: mah +creation_date: 2009-12-10T05:37:00Z + +[Term] +id: GO:0071332 +name: cellular response to fructose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus." [GOC:mah] +is_a: GO:0009750 ! response to fructose +is_a: GO:0071331 ! cellular response to hexose stimulus +created_by: mah +creation_date: 2009-12-10T05:37:39Z + +[Term] +id: GO:0071333 +name: cellular response to glucose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:mah] +is_a: GO:0001678 ! cellular glucose homeostasis +is_a: GO:0009749 ! response to glucose +is_a: GO:0071331 ! cellular response to hexose stimulus +created_by: mah +creation_date: 2009-12-10T05:38:03Z + +[Term] +id: GO:0071334 +name: cellular response to rhamnose stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus." [GOC:mah] +synonym: "cellular response to L-rhamnose stimulus" NARROW [GOC:mah] +is_a: GO:0032149 ! response to rhamnose +is_a: GO:0071331 ! cellular response to hexose stimulus +created_by: mah +creation_date: 2009-12-10T05:38:38Z + +[Term] +id: GO:0071335 +name: hair follicle cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population." [GOC:rph, PMID:16086254] +is_a: GO:0008283 ! cell population proliferation +created_by: mah +creation_date: 2009-12-11T10:49:53Z + +[Term] +id: GO:0071336 +name: regulation of hair follicle cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hair follicle cell proliferation." [GOC:mah] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071335 ! hair follicle cell proliferation +relationship: regulates GO:0071335 ! hair follicle cell proliferation +created_by: mah +creation_date: 2009-12-11T10:53:40Z + +[Term] +id: GO:0071337 +name: negative regulation of hair follicle cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation." [GOC:mah] +synonym: "down regulation of hair follicle cell proliferation" EXACT [GOC:mah] +synonym: "down-regulation of hair follicle cell proliferation" EXACT [GOC:mah] +synonym: "downregulation of hair follicle cell proliferation" EXACT [GOC:mah] +synonym: "inhibition of hair follicle cell proliferation" NARROW [GOC:mah] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0071336 ! regulation of hair follicle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071335 ! hair follicle cell proliferation +relationship: negatively_regulates GO:0071335 ! hair follicle cell proliferation +created_by: mah +creation_date: 2009-12-11T10:59:20Z + +[Term] +id: GO:0071338 +name: positive regulation of hair follicle cell proliferation +namespace: biological_process +def: "Any process that activates or increases the rate or extent of hair follicle cell proliferation." [GOC:mah] +synonym: "activation of hair follicle cell proliferation" NARROW [GOC:mah] +synonym: "stimulation of hair follicle cell proliferation" NARROW [GOC:mah] +synonym: "up regulation of hair follicle cell proliferation" EXACT [GOC:mah] +synonym: "up-regulation of hair follicle cell proliferation" EXACT [GOC:mah] +synonym: "upregulation of hair follicle cell proliferation" EXACT [GOC:mah] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0071336 ! regulation of hair follicle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071335 ! hair follicle cell proliferation +relationship: positively_regulates GO:0071335 ! hair follicle cell proliferation +created_by: mah +creation_date: 2009-12-11T11:00:57Z + +[Term] +id: GO:0071339 +name: MLL1 complex +namespace: cellular_component +def: "A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5." [GOC:sp, PMID:15960975] +is_a: GO:0044665 ! MLL1/2 complex +created_by: mah +creation_date: 2009-12-11T11:11:36Z + +[Term] +id: GO:0071340 +name: skeletal muscle acetylcholine-gated channel clustering +namespace: biological_process +def: "The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals." [GOC:bf, GOC:dsf, PMID:19285469] +synonym: "skeletal muscle AChR clustering" EXACT [GOC:mah] +synonym: "skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:bf] +is_a: GO:0043113 ! receptor clustering +relationship: part_of GO:0001941 ! postsynaptic membrane organization +relationship: part_of GO:0007528 ! neuromuscular junction development +created_by: mah +creation_date: 2009-12-11T11:13:55Z + +[Term] +id: GO:0071341 +name: medial cortical node +namespace: cellular_component +def: "A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis." [GOC:mah, GOC:vw, PMID:19474789, PMID:19959363] +synonym: "mid1p medial cortical dot" EXACT [GOC:vw] +synonym: "midsome" EXACT [GOC:vw, PMID:19959363] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031097 ! medial cortex +created_by: mah +creation_date: 2009-12-11T11:40:36Z + +[Term] +id: GO:0071342 +name: regulation of establishment of actomyosin contractile ring localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:mah] +synonym: "regulation of establishment of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle" RELATED [GOC:dph, GOC:tb] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:1901648 ! regulation of actomyosin contractile ring localization +is_a: GO:2000073 ! regulation of cytokinesis, site selection +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032188 ! establishment of actomyosin contractile ring localization +relationship: regulates GO:0032188 ! establishment of actomyosin contractile ring localization +created_by: mah +creation_date: 2009-12-11T01:22:11Z + +[Term] +id: GO:0071343 +name: obsolete negative regulation of establishment of actomyosin contractile ring localization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location." [GOC:mah] +comment: This term was made obsolete because it does not describe a wild-type or normal process. +synonym: "negative regulation of establishment of actomyosin contractile ring localization" EXACT [] +synonym: "negative regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:mah] +synonym: "negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:mah, GOC:vw] +synonym: "negative regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle" RELATED [GOC:dph, GOC:tb] +is_obsolete: true +created_by: mah +creation_date: 2009-12-11T01:33:14Z + +[Term] +id: GO:0071344 +name: diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid." [GOC:pde] +synonym: "pyrophosphate metabolism" EXACT [GOC:mah] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0043436 ! oxoacid metabolic process +created_by: mah +creation_date: 2009-12-11T01:43:41Z + +[Term] +id: GO:0071345 +name: cellular response to cytokine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus." [GOC:mah] +is_a: GO:0034097 ! response to cytokine +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-11T02:41:12Z + +[Term] +id: GO:0071346 +name: cellular response to interferon-gamma +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far." [GOC:mah, PR:000000017] +synonym: "cellular response to gamma-interferon" RELATED [GOC:mah] +synonym: "cellular response to immune interferon" EXACT [GOC:mah] +synonym: "cellular response to type II IFN" BROAD [GOC:mah] +synonym: "cellular response to type II interferon" BROAD [GOC:mah] +is_a: GO:0034341 ! response to interferon-gamma +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:48:00Z + +[Term] +id: GO:0071347 +name: cellular response to interleukin-1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus." [GOC:mah] +synonym: "cellular response to IL-1" EXACT [GOC:mah] +is_a: GO:0070555 ! response to interleukin-1 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:49:17Z + +[Term] +id: GO:0071348 +name: cellular response to interleukin-11 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus." [GOC:mah] +synonym: "cellular response to IL-11" EXACT [GOC:mah] +is_a: GO:0071105 ! response to interleukin-11 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:49:29Z + +[Term] +id: GO:0071349 +name: cellular response to interleukin-12 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus." [GOC:mah] +synonym: "cellular response to IL-12" EXACT [GOC:mah] +is_a: GO:0070671 ! response to interleukin-12 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:49:40Z + +[Term] +id: GO:0071350 +name: cellular response to interleukin-15 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus." [GOC:mah] +synonym: "cellular response to IL-15" EXACT [GOC:mah] +is_a: GO:0070672 ! response to interleukin-15 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:49:51Z + +[Term] +id: GO:0071351 +name: cellular response to interleukin-18 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus." [GOC:mah] +synonym: "cellular response to IL-18" EXACT [GOC:mah] +is_a: GO:0070673 ! response to interleukin-18 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:50:03Z + +[Term] +id: GO:0071352 +name: cellular response to interleukin-2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus." [GOC:mah] +synonym: "cellular response to IL-2" EXACT [GOC:mah] +is_a: GO:0070669 ! response to interleukin-2 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:50:48Z + +[Term] +id: GO:0071353 +name: cellular response to interleukin-4 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus." [GOC:mah] +synonym: "cellular response to IL-4" EXACT [GOC:mah] +is_a: GO:0070670 ! response to interleukin-4 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:51:00Z + +[Term] +id: GO:0071354 +name: cellular response to interleukin-6 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus." [GOC:mah] +synonym: "cellular response to IL-6" EXACT [GOC:mah] +is_a: GO:0070741 ! response to interleukin-6 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:51:14Z + +[Term] +id: GO:0071355 +name: cellular response to interleukin-9 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus." [GOC:mah] +synonym: "cellular response to IL-9" EXACT [GOC:mah] +is_a: GO:0071104 ! response to interleukin-9 +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:51:26Z + +[Term] +id: GO:0071356 +name: cellular response to tumor necrosis factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus." [GOC:mah] +synonym: "cellular response to TNF" EXACT [GOC:mah] +is_a: GO:0034612 ! response to tumor necrosis factor +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:51:37Z + +[Term] +id: GO:0071357 +name: cellular response to type I interferon +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families." [GOC:mah, PR:000025848] +synonym: "cellular response to type I IFN" EXACT [GOC:mah] +is_a: GO:0034340 ! response to type I interferon +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:51:47Z + +[Term] +id: GO:0071358 +name: cellular response to type III interferon +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far." [GOC:mah] +synonym: "cellular response to interferon-lambda" NARROW [GOC:mah] +synonym: "cellular response to type III IFN" EXACT [GOC:mah] +is_a: GO:0034342 ! response to type III interferon +is_a: GO:0071345 ! cellular response to cytokine stimulus +created_by: mah +creation_date: 2009-12-11T02:52:00Z + +[Term] +id: GO:0071359 +name: cellular response to dsRNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus." [GOC:mah] +synonym: "cellular response to double-stranded RNA" EXACT [GOC:mah] +is_a: GO:0043331 ! response to dsRNA +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: mah +creation_date: 2009-12-11T03:00:32Z + +[Term] +id: GO:0071360 +name: cellular response to exogenous dsRNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus." [GOC:mah] +synonym: "cellular response to exogenous double-stranded RNA" EXACT [GOC:mah] +synonym: "cellular response to viral dsRNA" NARROW [GOC:mah] +is_a: GO:0043330 ! response to exogenous dsRNA +is_a: GO:0071359 ! cellular response to dsRNA +created_by: mah +creation_date: 2009-12-11T03:02:00Z + +[Term] +id: GO:0071361 +name: cellular response to ethanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0045471 ! response to ethanol +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2009-12-11T03:02:59Z + +[Term] +id: GO:0071362 +name: cellular response to ether +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus." [GOC:mah] +is_a: GO:0045472 ! response to ether +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T03:03:22Z + +[Term] +id: GO:0071363 +name: cellular response to growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." [GOC:mah] +is_a: GO:0070848 ! response to growth factor +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-11T03:05:07Z + +[Term] +id: GO:0071364 +name: cellular response to epidermal growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus." [GOC:mah] +synonym: "cellular response to EGF stimulus" EXACT [GOC:mah] +is_a: GO:0070849 ! response to epidermal growth factor +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +created_by: mah +creation_date: 2009-12-11T03:05:34Z + +[Term] +id: GO:0071365 +name: cellular response to auxin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus." [GOC:mah] +is_a: GO:0009733 ! response to auxin +is_a: GO:0032870 ! cellular response to hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:10:22Z + +[Term] +id: GO:0071366 +name: cellular response to indolebutyric acid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus." [GOC:mah] +synonym: "cellular response to IBA stimulus" EXACT [GOC:mah] +synonym: "cellular response to indole-3-butyric acid stimulus" NARROW [GOC:mah] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071365 ! cellular response to auxin stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0080026 ! response to indolebutyric acid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T03:12:14Z + +[Term] +id: GO:0071367 +name: cellular response to brassinosteroid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus." [GOC:mah] +is_a: GO:0009741 ! response to brassinosteroid +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T03:13:33Z + +[Term] +id: GO:0071368 +name: cellular response to cytokinin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus." [GOC:mah] +is_a: GO:0009735 ! response to cytokinin +is_a: GO:0032870 ! cellular response to hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:13:47Z + +[Term] +id: GO:0071369 +name: cellular response to ethylene stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus." [GOC:mah] +synonym: "cellular response to ethene stimulus" EXACT [GOC:mah] +is_a: GO:0009723 ! response to ethylene +is_a: GO:0032870 ! cellular response to hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:13:57Z + +[Term] +id: GO:0071370 +name: cellular response to gibberellin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus." [GOC:mah] +synonym: "cellular response to gibberellic acid stimulus" NARROW [GOC:mah] +is_a: GO:0009739 ! response to gibberellin +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T03:14:21Z + +[Term] +id: GO:0071371 +name: cellular response to gonadotropin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus." [GOC:mah] +synonym: "cellular response to gonadotrophin stimulus" EXACT [GOC:dph] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0034698 ! response to gonadotropin +created_by: mah +creation_date: 2009-12-11T03:14:35Z + +[Term] +id: GO:0071372 +name: cellular response to follicle-stimulating hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus." [GOC:mah] +synonym: "cellular response to follicle stimulating hormone stimulus" EXACT [] +synonym: "cellular response to FSH stimulus" EXACT [] +is_a: GO:0032354 ! response to follicle-stimulating hormone +is_a: GO:0071371 ! cellular response to gonadotropin stimulus +created_by: mah +creation_date: 2009-12-11T03:15:56Z + +[Term] +id: GO:0071373 +name: cellular response to luteinizing hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus." [GOC:mah] +is_a: GO:0034699 ! response to luteinizing hormone +is_a: GO:0071371 ! cellular response to gonadotropin stimulus +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:16:02Z + +[Term] +id: GO:0071374 +name: cellular response to parathyroid hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071107 ! response to parathyroid hormone +created_by: mah +creation_date: 2009-12-11T03:19:29Z + +[Term] +id: GO:0071375 +name: cellular response to peptide hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [GOC:mah] +synonym: "cellular response to polypeptide hormone stimulus" EXACT [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0043434 ! response to peptide hormone +is_a: GO:1901653 ! cellular response to peptide +created_by: mah +creation_date: 2009-12-11T03:24:18Z + +[Term] +id: GO:0071376 +name: cellular response to corticotropin-releasing hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response." [GOC:mah] +synonym: "cellular response to corticoliberin stimulus" EXACT [GOC:mah] +synonym: "cellular response to corticotropin-releasing factor stimulus" EXACT [GOC:mah] +synonym: "cellular response to CRF stimulus" EXACT [GOC:mah] +synonym: "cellular response to CRH stimulus" EXACT [GOC:mah] +is_a: GO:0043435 ! response to corticotropin-releasing hormone +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:24:56Z + +[Term] +id: GO:0071377 +name: cellular response to glucagon stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:mah] +is_a: GO:0033762 ! response to glucagon +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:25:07Z + +[Term] +id: GO:0071378 +name: cellular response to growth hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth." [GOC:mah] +is_a: GO:0060416 ! response to growth hormone +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:25:17Z + +[Term] +id: GO:0071379 +name: cellular response to prostaglandin stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0034694 ! response to prostaglandin +is_a: GO:0071398 ! cellular response to fatty acid +created_by: mah +creation_date: 2009-12-11T03:33:52Z + +[Term] +id: GO:0071380 +name: cellular response to prostaglandin E stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus." [GOC:mah] +is_a: GO:0034695 ! response to prostaglandin E +is_a: GO:0071379 ! cellular response to prostaglandin stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T03:34:43Z + +[Term] +id: GO:0071381 +name: cellular response to prostaglandin F stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus." [GOC:mah] +is_a: GO:0034696 ! response to prostaglandin F +is_a: GO:0071379 ! cellular response to prostaglandin stimulus +created_by: mah +creation_date: 2009-12-11T03:34:57Z + +[Term] +id: GO:0071382 +name: cellular response to prostaglandin I stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus." [GOC:mah] +is_a: GO:0034697 ! response to prostaglandin I +is_a: GO:0071379 ! cellular response to prostaglandin stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-11T03:45:10Z + +[Term] +id: GO:0071383 +name: cellular response to steroid hormone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0048545 ! response to steroid hormone +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-11T03:49:02Z + +[Term] +id: GO:0071384 +name: cellular response to corticosteroid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids." [GOC:mah] +is_a: GO:0031960 ! response to corticosteroid +is_a: GO:0071383 ! cellular response to steroid hormone stimulus +created_by: mah +creation_date: 2009-12-11T03:52:07Z + +[Term] +id: GO:0071385 +name: cellular response to glucocorticoid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." [GOC:mah] +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0071384 ! cellular response to corticosteroid stimulus +created_by: mah +creation_date: 2009-12-11T03:53:56Z + +[Term] +id: GO:0071386 +name: cellular response to corticosterone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses." [GOC:mah] +is_a: GO:0051412 ! response to corticosterone +is_a: GO:0071385 ! cellular response to glucocorticoid stimulus +is_a: GO:0071389 ! cellular response to mineralocorticoid stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T03:57:44Z + +[Term] +id: GO:0071387 +name: cellular response to cortisol stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions." [GOC:mah] +synonym: "cellular response to hydrocortisone stimulus" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0051414 ! response to cortisol +is_a: GO:0071385 ! cellular response to glucocorticoid stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T03:57:55Z + +[Term] +id: GO:0071388 +name: cellular response to cortisone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues." [GOC:mah] +is_a: GO:0051413 ! response to cortisone +is_a: GO:0071385 ! cellular response to glucocorticoid stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T03:57:59Z + +[Term] +id: GO:0071389 +name: cellular response to mineralocorticoid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance." [GOC:mah] +is_a: GO:0051385 ! response to mineralocorticoid +is_a: GO:0071384 ! cellular response to corticosteroid stimulus +created_by: mah +creation_date: 2009-12-11T03:59:02Z + +[Term] +id: GO:0071390 +name: cellular response to ecdysone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035075 ! response to ecdysone +is_a: GO:0036315 ! cellular response to sterol +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T04:03:57Z + +[Term] +id: GO:0071391 +name: cellular response to estrogen stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics." [GOC:mah] +synonym: "cellular response to oestrogen stimulus" EXACT [GOC:mah] +is_a: GO:0043627 ! response to estrogen +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-11T04:09:56Z + +[Term] +id: GO:0071392 +name: cellular response to estradiol stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." [GOC:mah] +synonym: "cellular response to E2 stimulus" EXACT [GOC:mah] +is_a: GO:0032355 ! response to estradiol +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T04:10:31Z + +[Term] +id: GO:0071393 +name: cellular response to progesterone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus." [GOC:mah] +is_a: GO:0032570 ! response to progesterone +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071383 ! cellular response to steroid hormone stimulus +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T04:11:13Z + +[Term] +id: GO:0071394 +name: cellular response to testosterone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0033574 ! response to testosterone +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-11T04:11:29Z + +[Term] +id: GO:0071395 +name: cellular response to jasmonic acid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus." [GOC:mah] +is_a: GO:0009753 ! response to jasmonic acid +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T04:13:34Z + +[Term] +id: GO:0071396 +name: cellular response to lipid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:mah] +is_a: GO:0033993 ! response to lipid +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-11T04:37:10Z + +[Term] +id: GO:0071397 +name: cellular response to cholesterol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus." [GOC:mah] +is_a: GO:0036315 ! cellular response to sterol +is_a: GO:0070723 ! response to cholesterol +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2009-12-11T04:39:31Z + +[Term] +id: GO:0071398 +name: cellular response to fatty acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus." [GOC:mah] +is_a: GO:0070542 ! response to fatty acid +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T04:39:56Z + +[Term] +id: GO:0071399 +name: cellular response to linoleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus." [GOC:mah] +synonym: "cellular response to linoleate" EXACT [GOC:mah] +is_a: GO:0070543 ! response to linoleic acid +is_a: GO:0071398 ! cellular response to fatty acid +created_by: mah +creation_date: 2009-12-11T04:40:22Z + +[Term] +id: GO:0071400 +name: cellular response to oleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus." [GOC:mah] +synonym: "cellular response to oleate" EXACT [GOC:mah] +is_a: GO:0034201 ! response to oleic acid +is_a: GO:0071398 ! cellular response to fatty acid +created_by: mah +creation_date: 2009-12-11T04:40:38Z + +[Term] +id: GO:0071401 +name: cellular response to triglyceride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus." [GOC:mah] +synonym: "cellular response to triacylglyceride" EXACT [GOC:mah] +synonym: "cellular response to triacylglycerol" EXACT [GOC:mah] +is_a: GO:0034014 ! response to triglyceride +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-11T04:40:56Z + +[Term] +id: GO:0071402 +name: cellular response to lipoprotein particle stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus." [GOC:mah] +is_a: GO:0051716 ! cellular response to stimulus +created_by: mah +creation_date: 2009-12-14T02:48:51Z + +[Term] +id: GO:0071403 +name: cellular response to high density lipoprotein particle stimulus +namespace: biological_process +alt_id: GO:0055099 +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus." [GOC:mah] +synonym: "cellular response to high-density lipoprotein particle stimulus" EXACT [] +synonym: "response to high density lipoprotein particle" BROAD [] +synonym: "response to high density lipoprotein particle stimulus" BROAD [GOC:dos] +is_a: GO:0071402 ! cellular response to lipoprotein particle stimulus +created_by: mah +creation_date: 2009-12-14T02:51:43Z + +[Term] +id: GO:0071404 +name: cellular response to low-density lipoprotein particle stimulus +namespace: biological_process +alt_id: GO:0055098 +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus." [GOC:mah] +synonym: "response to low density lipoprotein particle" BROAD [] +synonym: "response to low-density lipoprotein particle" BROAD [GOC:dos] +synonym: "response to low-density lipoprotein particle stimulus" BROAD [] +is_a: GO:0055094 ! response to lipoprotein particle +is_a: GO:0071402 ! cellular response to lipoprotein particle stimulus +created_by: mah +creation_date: 2009-12-14T02:51:57Z + +[Term] +id: GO:0071405 +name: cellular response to methanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus." [GOC:mah] +is_a: GO:0033986 ! response to methanol +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2009-12-14T02:54:44Z + +[Term] +id: GO:0071406 +name: cellular response to methylmercury +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus." [GOC:mah] +synonym: "cellular response to CH3-Hg+" EXACT [GOC:mah] +synonym: "cellular response to MeHg+" EXACT [GOC:mah] +is_a: GO:0051597 ! response to methylmercury +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-14T02:55:12Z + +[Term] +id: GO:0071407 +name: cellular response to organic cyclic compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:mah] +synonym: "cellular response to organic cyclic substance" EXACT [GOC:mah] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-14T02:55:58Z + +[Term] +id: GO:0071408 +name: cellular response to cycloalkane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n." [GOC:mah] +is_a: GO:0014071 ! response to cycloalkane +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-14T02:57:15Z + +[Term] +id: GO:0071409 +name: cellular response to cycloheximide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes." [GOC:mah] +synonym: "cellular response to actidione" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0046898 ! response to cycloheximide +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2009-12-14T02:57:24Z + +[Term] +id: GO:0071410 +name: cellular response to cyclopentenone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid." [GOC:mah] +is_a: GO:0010583 ! response to cyclopentenone +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-14T03:09:49Z + +[Term] +id: GO:0071411 +name: cellular response to fluoxetine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor." [GOC:mah, GOC:pr] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0014076 ! response to fluoxetine +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +created_by: mah +creation_date: 2009-12-14T03:09:58Z + +[Term] +id: GO:0071412 +name: cellular response to genistein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus." [GOC:mah] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0033595 ! response to genistein +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071413 ! cellular response to hydroxyisoflavone +created_by: mah +creation_date: 2009-12-14T03:10:04Z + +[Term] +id: GO:0071413 +name: cellular response to hydroxyisoflavone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus." [GOC:mah] +is_a: GO:0033594 ! response to hydroxyisoflavone +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1905546 ! cellular response to phenylpropanoid +created_by: mah +creation_date: 2009-12-14T03:10:09Z + +[Term] +id: GO:0071414 +name: cellular response to methotrexate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase." [GOC:mah] +is_a: GO:0031427 ! response to methotrexate +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-14T03:10:30Z + +[Term] +id: GO:0071415 +name: cellular response to purine-containing compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus." [GOC:mah] +synonym: "cellular response to purine" RELATED [] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-14T03:12:20Z + +[Term] +id: GO:0071416 +name: cellular response to tropane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine." [GOC:mah] +is_a: GO:0014073 ! response to tropane +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071407 ! cellular response to organic cyclic compound +created_by: mah +creation_date: 2009-12-14T03:12:24Z + +[Term] +id: GO:0071417 +name: cellular response to organonitrogen compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [GOC:mah] +synonym: "cellular response to organic nitrogen" EXACT [GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: mah +creation_date: 2009-12-14T04:07:27Z + +[Term] +id: GO:0071418 +name: cellular response to amine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:mah] +is_a: GO:0014075 ! response to amine +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-14T04:08:17Z + +[Term] +id: GO:0071419 +name: cellular response to amphetamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine." [GOC:mah] +is_a: GO:0001975 ! response to amphetamine +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071418 ! cellular response to amine stimulus +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:0097237 ! cellular response to toxic substance +created_by: mah +creation_date: 2009-12-14T04:09:02Z + +[Term] +id: GO:0071420 +name: cellular response to histamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." [GOC:mah] +synonym: "cellular response to histamine stimulus" EXACT [GOC:mah] +is_a: GO:0034776 ! response to histamine +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +created_by: mah +creation_date: 2009-12-14T04:09:25Z + +[Term] +id: GO:0071421 +name: manganese ion transmembrane transport +namespace: biological_process +def: "A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "manganese ion membrane transport" EXACT [] +synonym: "transmembrane manganese transport" EXACT [GOC:mah] +is_a: GO:0006828 ! manganese ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2009-12-15T02:41:31Z + +[Term] +id: GO:0071422 +name: succinate transmembrane transport +namespace: biological_process +def: "The process in which succinate is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "succinate membrane transport" EXACT [] +synonym: "transmembrane succinate transport" EXACT [GOC:mah] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015744 ! succinate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: mah +creation_date: 2009-12-15T03:29:44Z + +[Term] +id: GO:0071423 +name: malate transmembrane transport +namespace: biological_process +def: "A process in which a malate ion is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "malate membrane transport" EXACT [] +synonym: "transmembrane malate transport" EXACT [GOC:mah] +is_a: GO:0015743 ! malate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: mah +creation_date: 2009-12-15T03:31:37Z + +[Term] +id: GO:0071424 +name: rRNA (cytosine-N4-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine." [GOC:imk, PMID:19965768] +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0016434 ! rRNA (cytosine) methyltransferase activity +created_by: mah +creation_date: 2009-12-15T03:46:52Z + +[Term] +id: GO:0071425 +name: hematopoietic stem cell proliferation +namespace: biological_process +def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl] +synonym: "hemopoietic stem cell proliferation" EXACT [] +is_a: GO:0072089 ! stem cell proliferation +relationship: part_of GO:0030097 ! hemopoiesis +created_by: mah +creation_date: 2009-12-16T10:22:52Z + +[Term] +id: GO:0071426 +name: ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm." [GOC:mah] +synonym: "ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0006405 ! RNA export from nucleus +is_a: GO:0006611 ! protein export from nucleus +is_a: GO:0031503 ! protein-containing complex localization +relationship: part_of GO:0071166 ! ribonucleoprotein complex localization +created_by: mah +creation_date: 2009-12-16T10:13:01Z + +[Term] +id: GO:0071427 +name: mRNA-containing ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm." [GOC:mah] +synonym: "mRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "mRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "mRNA-containing RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0071426 ! ribonucleoprotein complex export from nucleus +created_by: mah +creation_date: 2009-12-16T10:13:59Z + +[Term] +id: GO:0071428 +name: rRNA-containing ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm." [GOC:mah] +synonym: "rRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "rRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "rRNA-containing RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0071426 ! ribonucleoprotein complex export from nucleus +created_by: mah +creation_date: 2009-12-16T10:15:07Z + +[Term] +id: GO:0071429 +name: snRNA-containing ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm." [GOC:mah] +synonym: "snRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "snRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "snRNA-containing RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0071426 ! ribonucleoprotein complex export from nucleus +relationship: has_part GO:0006408 ! snRNA export from nucleus +created_by: mah +creation_date: 2009-12-16T10:15:38Z + +[Term] +id: GO:0071430 +name: pre-miRNA-containing ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm." [GOC:mah, GOC:sl] +synonym: "pre-microRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "pre-microRNA-containing ribonucleoprotein complex export from nucleus" EXACT [] +synonym: "pre-microRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "pre-microRNA-containing RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0071426 ! ribonucleoprotein complex export from nucleus +relationship: has_part GO:0035281 ! pre-miRNA export from nucleus +created_by: mah +creation_date: 2009-12-16T10:26:16Z + +[Term] +id: GO:0071431 +name: tRNA-containing ribonucleoprotein complex export from nucleus +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm." [GOC:mah] +synonym: "tRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah] +synonym: "tRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah] +synonym: "tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "tRNA-containing RNP export from nucleus" EXACT [GOC:mah] +is_a: GO:0071426 ! ribonucleoprotein complex export from nucleus +created_by: mah +creation_date: 2009-12-16T10:27:03Z + +[Term] +id: GO:0071432 +name: peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion." [GOC:mah] +synonym: "a-factor processing (proteolytic)" NARROW [GOC:vw] +synonym: "alpha-factor maturation" NARROW [GOC:vw] +synonym: "mating-type peptide pheromone maturation involved in conjugation with cellular fusion" EXACT [GOC:mah] +synonym: "peptide mating pheromone formation involved in conjugation with cellular fusion" EXACT [GOC:mah] +synonym: "peptide mating pheromone processing involved in conjugation with cellular fusion" EXACT [GOC:mah] +is_a: GO:0007323 ! peptide pheromone maturation +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +created_by: mah +creation_date: 2009-12-16T10:46:50Z + +[Term] +id: GO:0071433 +name: cell wall repair +namespace: biological_process +def: "A process of cell wall organization that results in the restoration of the cell wall following damage." [GOC:mah, GOC:vw] +is_a: GO:0071555 ! cell wall organization +created_by: mah +creation_date: 2009-12-16T11:00:50Z + +[Term] +id: GO:0071434 +name: cell chemotaxis to angiotensin +namespace: biological_process +def: "The directed movement of a motile cell in response to the presence of angiotensin." [GOC:mah] +synonym: "angiotensin mediated chemotaxis" BROAD [GOC:mah] +synonym: "angiotensin-mediated cell chemotaxis" EXACT [GOC:mah] +is_a: GO:0060326 ! cell chemotaxis +created_by: mah +creation_date: 2009-12-16T11:07:15Z + +[Term] +id: GO:0071437 +name: invadopodium +namespace: cellular_component +def: "A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate." [GOC:mah, PMID:16651416, PMID:19491051, PMID:19931459] +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: mah +creation_date: 2009-12-16T02:19:58Z + +[Term] +id: GO:0071438 +name: invadopodium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding an invadopodium." [GOC:mah] +is_a: GO:0031253 ! cell projection membrane +relationship: part_of GO:0071437 ! invadopodium +created_by: mah +creation_date: 2009-12-16T03:00:30Z + +[Term] +id: GO:0071439 +name: clathrin complex +namespace: cellular_component +def: "A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface." [GOC:mah, PMID:16493411] +synonym: "clathrin triskelion" EXACT [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030118 ! clathrin coat +created_by: mah +creation_date: 2009-12-16T03:17:58Z + +[Term] +id: GO:0071440 +name: regulation of histone H3-K14 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone." [GOC:mah] +synonym: "regulation of histone H3 acetylation at K14" EXACT [GOC:mah] +synonym: "regulation of histone H3K14 acetylation" EXACT [GOC:mah] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044154 ! histone H3-K14 acetylation +relationship: regulates GO:0044154 ! histone H3-K14 acetylation +created_by: mah +creation_date: 2009-12-16T03:24:53Z + +[Term] +id: GO:0071441 +name: negative regulation of histone H3-K14 acetylation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone." [GOC:mah] +synonym: "down regulation of histone H3-K14 acetylation" EXACT [GOC:mah] +synonym: "down-regulation of histone H3-K14 acetylation" EXACT [GOC:mah] +synonym: "downregulation of histone H3-K14 acetylation" EXACT [GOC:mah] +synonym: "inhibition of histone H3-K14 acetylation" NARROW [GOC:mah] +synonym: "negative regulation of histone H3 acetylation at K14" EXACT [GOC:mah] +synonym: "negative regulation of histone H3K14 acetylation" EXACT [GOC:mah] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:0071440 ! regulation of histone H3-K14 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044154 ! histone H3-K14 acetylation +relationship: negatively_regulates GO:0044154 ! histone H3-K14 acetylation +created_by: mah +creation_date: 2009-12-16T03:28:23Z + +[Term] +id: GO:0071442 +name: positive regulation of histone H3-K14 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone." [GOC:mah] +synonym: "activation of histone H3-K14 acetylation" NARROW [GOC:mah] +synonym: "positive regulation of histone H3 acetylation at K14" EXACT [GOC:mah] +synonym: "positive regulation of histone H3K14 acetylation" EXACT [GOC:mah] +synonym: "stimulation of histone H3-K14 acetylation" NARROW [GOC:mah] +synonym: "up regulation of histone H3-K14 acetylation" EXACT [GOC:mah] +synonym: "up-regulation of histone H3-K14 acetylation" EXACT [GOC:mah] +synonym: "upregulation of histone H3-K14 acetylation" EXACT [GOC:mah] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:0071440 ! regulation of histone H3-K14 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044154 ! histone H3-K14 acetylation +relationship: positively_regulates GO:0044154 ! histone H3-K14 acetylation +created_by: mah +creation_date: 2009-12-16T03:29:49Z + +[Term] +id: GO:0071443 +name: tDNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with DNA sequences encoding transfer RNA." [GOC:mah] +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding +created_by: mah +creation_date: 2009-12-16T03:47:31Z + +[Term] +id: GO:0071444 +name: cellular response to pheromone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus." [GOC:mah] +synonym: "cellular pheromone response" EXACT [GOC:mah] +is_a: GO:0019236 ! response to pheromone +is_a: GO:0071310 ! cellular response to organic substance +created_by: mah +creation_date: 2009-12-16T04:05:33Z + +[Term] +id: GO:0071445 +name: obsolete cellular response to protein stimulus +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus." [GOC:mah] +comment: This term was made obsolete because more specific terms exist. +synonym: "cellular response to protein stimulus" EXACT [] +is_obsolete: true +consider: GO:0032870 +consider: GO:0034620 +consider: GO:0071218 +consider: GO:0071345 +consider: GO:0071363 +created_by: mah +creation_date: 2009-12-16T04:12:04Z + +[Term] +id: GO:0071446 +name: cellular response to salicylic acid stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus." [GOC:mah] +synonym: "cellular response to salicylate stimulus" EXACT [GOC:dph] +is_a: GO:0009751 ! response to salicylic acid +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-16T04:14:16Z + +[Term] +id: GO:0071447 +name: cellular response to hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH." [GOC:mah] +is_a: GO:0033194 ! response to hydroperoxide +is_a: GO:0034599 ! cellular response to oxidative stress +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-16T04:16:42Z + +[Term] +id: GO:0071448 +name: cellular response to alkyl hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group." [GOC:mah] +is_a: GO:0033195 ! response to alkyl hydroperoxide +is_a: GO:0071447 ! cellular response to hydroperoxide +created_by: mah +creation_date: 2009-12-16T04:17:52Z + +[Term] +id: GO:0071449 +name: cellular response to lipid hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids." [GOC:mah] +synonym: "cellular response to LHPO" EXACT [GOC:mah] +is_a: GO:0006982 ! response to lipid hydroperoxide +is_a: GO:0071447 ! cellular response to hydroperoxide +created_by: mah +creation_date: 2009-12-16T04:17:57Z + +[Term] +id: GO:0071450 +name: cellular response to oxygen radical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." [GOC:mah] +is_a: GO:0000305 ! response to oxygen radical +is_a: GO:0034614 ! cellular response to reactive oxygen species +created_by: mah +creation_date: 2009-12-16T04:38:52Z + +[Term] +id: GO:0071451 +name: cellular response to superoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:mah] +is_a: GO:0000303 ! response to superoxide +is_a: GO:0071450 ! cellular response to oxygen radical +created_by: mah +creation_date: 2009-12-16T04:39:14Z + +[Term] +id: GO:0071452 +name: cellular response to singlet oxygen +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst." [GOC:mah] +is_a: GO:0000304 ! response to singlet oxygen +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0034614 ! cellular response to reactive oxygen species +is_a: GO:0035690 ! cellular response to drug +created_by: mah +creation_date: 2009-12-16T04:39:46Z + +[Term] +id: GO:0071453 +name: cellular response to oxygen levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:mah] +synonym: "cellular response to oxygen" RELATED [GOC:al] +is_a: GO:0070482 ! response to oxygen levels +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-16T04:43:59Z + +[Term] +id: GO:0071454 +name: cellular response to anoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." [GOC:mah] +comment: Note that this term should not be confused with 'cellular response to hypoxia ; GO:0071456'. +synonym: "cellular response to anaerobic conditions" EXACT [GOC:elh] +synonym: "cellular response to anoxic stress" EXACT [GOC:mah] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0034059 ! response to anoxia +is_a: GO:0036294 ! cellular response to decreased oxygen levels +created_by: mah +creation_date: 2009-12-16T04:44:20Z + +[Term] +id: GO:0071455 +name: cellular response to hyperoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension." [GOC:mah] +synonym: "cellular response to hyperoxic stress" EXACT [GOC:mah] +synonym: "cellular response to increased oxygen tension" EXACT [GOC:mah] +is_a: GO:0036295 ! cellular response to increased oxygen levels +is_a: GO:0055093 ! response to hyperoxia +is_a: GO:0062197 ! cellular response to chemical stress +created_by: mah +creation_date: 2009-12-16T04:44:41Z + +[Term] +id: GO:0071456 +name: cellular response to hypoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:mah] +comment: Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. +synonym: "cellular response to hypoxic stress" EXACT [GOC:mah] +synonym: "cellular response to lowered oxygen tension" EXACT [GOC:mah] +is_a: GO:0001666 ! response to hypoxia +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0036294 ! cellular response to decreased oxygen levels +created_by: mah +creation_date: 2009-12-16T04:45:20Z + +[Term] +id: GO:0071457 +name: cellular response to ozone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus." [GOC:mah] +is_a: GO:0010193 ! response to ozone +is_a: GO:0034614 ! cellular response to reactive oxygen species +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071236 ! cellular response to antibiotic +created_by: mah +creation_date: 2009-12-16T04:45:59Z + +[Term] +id: GO:0071458 +name: integral component of cytoplasmic side of endoplasmic reticulum membrane +namespace: cellular_component +def: "The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to cytosolic leaflet of endoplasmic reticulum membrane" EXACT [GOC:ab] +synonym: "integral to cytosolic side of endoplasmic reticulum membrane" EXACT [] +synonym: "integral to cytosolic side of ER membrane" EXACT [GOC:mah] +synonym: "integral to ER membrane, cytosolic side" EXACT [GOC:vw] +is_a: GO:0030176 ! integral component of endoplasmic reticulum membrane +intersection_of: GO:0030176 ! integral component of endoplasmic reticulum membrane +intersection_of: part_of GO:0098554 ! cytoplasmic side of endoplasmic reticulum membrane +relationship: part_of GO:0098554 ! cytoplasmic side of endoplasmic reticulum membrane +created_by: mah +creation_date: 2009-12-17T01:43:33Z + +[Term] +id: GO:0071459 +name: protein localization to chromosome, centromeric region +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome." [GOC:mah] +synonym: "protein localisation to chromosome, centromeric region" EXACT [GOC:mah] +synonym: "protein localization to centromere" EXACT [GOC:mah] +synonym: "protein localization to chromosome, centric region" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome +created_by: mah +creation_date: 2009-12-17T02:11:23Z + +[Term] +id: GO:0071460 +name: cellular response to cell-matrix adhesion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion." [GOC:sl, PMID:11425869] +is_a: GO:0031668 ! cellular response to extracellular stimulus +created_by: mah +creation_date: 2009-12-17T02:25:45Z + +[Term] +id: GO:0071461 +name: cellular response to redox state +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important." [GOC:mah] +synonym: "cellular redox signal response" EXACT [GOC:mah] +is_a: GO:0051775 ! response to redox state +created_by: mah +creation_date: 2009-12-18T11:30:21Z + +[Term] +id: GO:0071462 +name: cellular response to water stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." [GOC:mah] +is_a: GO:0009415 ! response to water +is_a: GO:0071214 ! cellular response to abiotic stimulus +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-18T11:32:44Z + +[Term] +id: GO:0071463 +name: cellular response to humidity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere." [GOC:mah] +is_a: GO:0009270 ! response to humidity +is_a: GO:0071462 ! cellular response to water stimulus +created_by: mah +creation_date: 2009-12-18T11:33:55Z + +[Term] +id: GO:0071464 +name: cellular response to hydrostatic pressure +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it." [GOC:mah] +synonym: "cellular response to biomechanical stress" BROAD [GOC:mah] +synonym: "cellular response to static fluid pressure" EXACT [GOC:mah] +is_a: GO:0051599 ! response to hydrostatic pressure +is_a: GO:0062197 ! cellular response to chemical stress +is_a: GO:0071462 ! cellular response to water stimulus +created_by: mah +creation_date: 2009-12-18T11:34:07Z + +[Term] +id: GO:0071465 +name: cellular response to desiccation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." [GOC:mah] +synonym: "desiccation tolerance" RELATED [GOC:mah] +is_a: GO:0009269 ! response to desiccation +is_a: GO:0042631 ! cellular response to water deprivation +created_by: mah +creation_date: 2009-12-18T11:35:19Z + +[Term] +id: GO:0071466 +name: cellular response to xenobiotic stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms." [GOC:mah] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: mah +creation_date: 2009-12-18T11:38:48Z + +[Term] +id: GO:0071467 +name: cellular response to pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:mah, Wikipedia:PH] +is_a: GO:0009268 ! response to pH +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-18T11:41:54Z + +[Term] +id: GO:0071468 +name: cellular response to acidic pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:go_curators, GOC:mah, Wikipedia:PH] +comment: This term should be used to annotate instances where a cell is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0071229 'cellular response to acid chemical'. +synonym: "cellular response to acidity" BROAD [] +is_a: GO:0010447 ! response to acidic pH +is_a: GO:0071467 ! cellular response to pH +created_by: mah +creation_date: 2009-12-18T11:42:35Z + +[Term] +id: GO:0071469 +name: cellular response to alkaline pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution." [GOC:go_curators, GOC:mah, Wikipedia:PH] +synonym: "cellular response to alkalinity" BROAD [] +synonym: "cellular response to basic pH" EXACT [GOC:mah] +is_a: GO:0010446 ! response to alkaline pH +is_a: GO:0071467 ! cellular response to pH +created_by: mah +creation_date: 2009-12-18T11:42:47Z + +[Term] +id: GO:0071470 +name: cellular response to osmotic stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] +synonym: "cellular osmotic response" EXACT [GOC:mah] +synonym: "cellular osmotic stress response" EXACT [GOC:mah] +is_a: GO:0006970 ! response to osmotic stress +is_a: GO:0062197 ! cellular response to chemical stress +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-18T11:45:33Z + +[Term] +id: GO:0071471 +name: cellular response to non-ionic osmotic stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment." [GOC:mah] +is_a: GO:0010335 ! response to non-ionic osmotic stress +is_a: GO:0071470 ! cellular response to osmotic stress +created_by: mah +creation_date: 2009-12-18T11:47:59Z + +[Term] +id: GO:0071472 +name: cellular response to salt stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:mah] +synonym: "cellular response to ionic osmotic stress" EXACT [GOC:mah] +synonym: "cellular salinity response" EXACT [GOC:mah] +is_a: GO:0009651 ! response to salt stress +is_a: GO:0071470 ! cellular response to osmotic stress +created_by: mah +creation_date: 2009-12-18T11:48:23Z + +[Term] +id: GO:0071473 +name: cellular response to cation stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment." [GOC:mah] +is_a: GO:0043157 ! response to cation stress +is_a: GO:0071472 ! cellular response to salt stress +created_by: mah +creation_date: 2009-12-18T11:49:46Z + +[Term] +id: GO:0071474 +name: cellular hyperosmotic response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell." [GOC:mah] +synonym: "cellular HOG response" EXACT [GOC:mah] +synonym: "cellular hypertonic response" EXACT [GOC:mah] +synonym: "cellular response to hypertonicity" EXACT [GOC:mah, GOC:yaf] +is_a: GO:0006972 ! hyperosmotic response +is_a: GO:0071470 ! cellular response to osmotic stress +created_by: mah +creation_date: 2009-12-18T11:51:36Z + +[Term] +id: GO:0071475 +name: cellular hyperosmotic salinity response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:mah] +synonym: "cellular response to hyperosmotic salt stress" EXACT [GOC:mah] +is_a: GO:0042538 ! hyperosmotic salinity response +is_a: GO:0071472 ! cellular response to salt stress +is_a: GO:0071474 ! cellular hyperosmotic response +created_by: mah +creation_date: 2009-12-18T11:52:06Z + +[Term] +id: GO:0071476 +name: cellular hypotonic response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell." [GOC:mah] +synonym: "cellular hypo-osmotic response" EXACT [GOC:mah] +is_a: GO:0006971 ! hypotonic response +is_a: GO:0071470 ! cellular response to osmotic stress +created_by: mah +creation_date: 2009-12-18T11:52:59Z + +[Term] +id: GO:0071477 +name: cellular hypotonic salinity response +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:mah] +synonym: "cellular response to hypotonic salt stress" EXACT [GOC:mah] +is_a: GO:0042539 ! hypotonic salinity response +is_a: GO:0071472 ! cellular response to salt stress +is_a: GO:0071476 ! cellular hypotonic response +created_by: mah +creation_date: 2009-12-18T11:53:20Z + +[Term] +id: GO:0071478 +name: cellular response to radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:mah] +comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength. +synonym: "cellular response to electromagnetic radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to radiation stimulus" EXACT [GOC:mah] +is_a: GO:0009314 ! response to radiation +is_a: GO:0071214 ! cellular response to abiotic stimulus +created_by: mah +creation_date: 2009-12-18T01:59:37Z + +[Term] +id: GO:0071479 +name: cellular response to ionizing radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." [GOC:mah] +synonym: "cellular response to ionising radiation" EXACT [GOC:mah] +synonym: "cellular response to ionizing radiation stimulus" EXACT [GOC:mah] +is_a: GO:0010212 ! response to ionizing radiation +is_a: GO:0071478 ! cellular response to radiation +created_by: mah +creation_date: 2009-12-18T02:00:31Z + +[Term] +id: GO:0071480 +name: cellular response to gamma radiation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." [GOC:mah] +synonym: "cellular response to gamma ray" RELATED [GOC:mah] +synonym: "cellular response to gamma-ray photon" RELATED [GOC:mah] +is_a: GO:0010332 ! response to gamma radiation +is_a: GO:0071479 ! cellular response to ionizing radiation +created_by: mah +creation_date: 2009-12-18T02:00:50Z + +[Term] +id: GO:0071481 +name: cellular response to X-ray +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)." [GOC:mah] +synonym: "cellular response to X-ray radiation stimulus" EXACT [GOC:mah] +is_a: GO:0010165 ! response to X-ray +is_a: GO:0071479 ! cellular response to ionizing radiation +created_by: mah +creation_date: 2009-12-18T02:00:59Z + +[Term] +id: GO:0071482 +name: cellular response to light stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:mah] +is_a: GO:0009416 ! response to light stimulus +is_a: GO:0071478 ! cellular response to radiation +created_by: mah +creation_date: 2009-12-18T02:03:49Z + +[Term] +id: GO:0071483 +name: cellular response to blue light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm." [GOC:mah] +synonym: "cellular response to blue light stimulus" EXACT [GOC:mah] +is_a: GO:0009637 ! response to blue light +is_a: GO:0071482 ! cellular response to light stimulus +created_by: mah +creation_date: 2009-12-18T02:09:48Z + +[Term] +id: GO:0071484 +name: cellular response to light intensity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus." [GOC:mah] +is_a: GO:0009642 ! response to light intensity +is_a: GO:0071482 ! cellular response to light stimulus +created_by: mah +creation_date: 2009-12-18T02:11:03Z + +[Term] +id: GO:0071485 +name: cellular response to absence of light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli." [GOC:mah] +synonym: "cellular response to darkness" RELATED [] +is_a: GO:0009646 ! response to absence of light +is_a: GO:0071484 ! cellular response to light intensity +created_by: mah +creation_date: 2009-12-18T02:13:12Z + +[Term] +id: GO:0071486 +name: cellular response to high light intensity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus." [GOC:mah] +is_a: GO:0009644 ! response to high light intensity +is_a: GO:0071484 ! cellular response to light intensity +created_by: mah +creation_date: 2009-12-18T02:13:23Z + +[Term] +id: GO:0071487 +name: cellular response to low light intensity stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2." [GOC:mah] +is_a: GO:0009645 ! response to low light intensity stimulus +is_a: GO:0071484 ! cellular response to light intensity +created_by: mah +creation_date: 2009-12-18T02:13:29Z + +[Term] +id: GO:0071488 +name: cellular response to very low light intensity stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec." [GOC:mah] +is_a: GO:0055122 ! response to very low light intensity stimulus +is_a: GO:0071484 ! cellular response to light intensity +created_by: mah +creation_date: 2009-12-18T02:13:40Z + +[Term] +id: GO:0071489 +name: cellular response to red or far red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mah] +is_a: GO:0009639 ! response to red or far red light +is_a: GO:0071482 ! cellular response to light stimulus +created_by: mah +creation_date: 2009-12-18T02:18:25Z + +[Term] +id: GO:0071490 +name: cellular response to far red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mah] +synonym: "cellular response to far red light stimulus" EXACT [GOC:mah] +is_a: GO:0010218 ! response to far red light +is_a: GO:0071489 ! cellular response to red or far red light +created_by: mah +creation_date: 2009-12-18T02:19:40Z + +[Term] +id: GO:0071491 +name: cellular response to red light +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs." [GOC:mah] +synonym: "cellular response to red light stimulus" EXACT [GOC:mah] +is_a: GO:0010114 ! response to red light +is_a: GO:0071489 ! cellular response to red or far red light +created_by: mah +creation_date: 2009-12-18T02:19:47Z + +[Term] +id: GO:0071492 +name: cellular response to UV-A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm." [GOC:mah] +synonym: "cellular response to UV-A light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UV-A radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVA light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVA radiation stimulus" EXACT [GOC:mah] +is_a: GO:0034644 ! cellular response to UV +is_a: GO:0070141 ! response to UV-A +created_by: mah +creation_date: 2009-12-18T02:21:51Z + +[Term] +id: GO:0071493 +name: cellular response to UV-B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm." [GOC:mah] +synonym: "cellular response to medium wave ultraviolet light stimulus" EXACT [GOC:mah] +synonym: "cellular response to medium wave ultraviolet radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to UV-B light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UV-B radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVB light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVB radiation stimulus" EXACT [GOC:mah] +is_a: GO:0010224 ! response to UV-B +is_a: GO:0034644 ! cellular response to UV +created_by: mah +creation_date: 2009-12-18T02:21:56Z + +[Term] +id: GO:0071494 +name: cellular response to UV-C +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm." [GOC:mah] +synonym: "cellular response to germicidal ultraviolet light stimulus" EXACT [GOC:mah] +synonym: "cellular response to germicidal ultraviolet radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to shortwave ultraviolet light stimulus" EXACT [GOC:mah] +synonym: "cellular response to shortwave ultraviolet radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to UV-C light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UV-C radiation stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVC light stimulus" EXACT [GOC:mah] +synonym: "cellular response to UVC radiation stimulus" EXACT [GOC:mah] +is_a: GO:0010225 ! response to UV-C +is_a: GO:0034644 ! cellular response to UV +created_by: mah +creation_date: 2009-12-18T02:22:01Z + +[Term] +id: GO:0071495 +name: cellular response to endogenous stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0009719 ! response to endogenous stimulus +created_by: mah +creation_date: 2009-12-18T02:25:40Z + +[Term] +id: GO:0071496 +name: cellular response to external stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:mah] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0009605 ! response to external stimulus +created_by: mah +creation_date: 2009-12-18T02:36:52Z + +[Term] +id: GO:0071497 +name: cellular response to freezing +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius." [GOC:mah] +synonym: "antifreeze activity" RELATED [GOC:mah] +synonym: "ice nucleation inhibitor activity" RELATED [GOC:mah] +is_a: GO:0050826 ! response to freezing +is_a: GO:0070417 ! cellular response to cold +created_by: mah +creation_date: 2009-12-18T02:41:02Z + +[Term] +id: GO:0071498 +name: cellular response to fluid shear stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface." [GOC:mah] +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0034405 ! response to fluid shear stress +created_by: mah +creation_date: 2009-12-18T02:41:44Z + +[Term] +id: GO:0071499 +name: cellular response to laminar fluid shear stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers." [GOC:mah] +is_a: GO:0034616 ! response to laminar fluid shear stress +is_a: GO:0071498 ! cellular response to fluid shear stress +created_by: mah +creation_date: 2009-12-18T02:43:02Z + +[Term] +id: GO:0071500 +name: cellular response to nitrosative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [GOC:mah] +is_a: GO:0051409 ! response to nitrosative stress +is_a: GO:0062197 ! cellular response to chemical stress +created_by: mah +creation_date: 2009-12-18T02:49:46Z + +[Term] +id: GO:0071501 +name: cellular response to sterol depletion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:mah] +synonym: "cellular sterol depletion response" EXACT [GOC:mah] +is_a: GO:0006991 ! response to sterol depletion +is_a: GO:0033554 ! cellular response to stress +created_by: mah +creation_date: 2009-12-18T02:54:14Z + +[Term] +id: GO:0071502 +name: cellular response to temperature stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." [GOC:mah] +synonym: "cellular response to thermal stimulus" EXACT [GOC:mah] +is_a: GO:0009266 ! response to temperature stimulus +created_by: mah +creation_date: 2009-12-18T02:56:45Z + +[Term] +id: GO:0071503 +name: response to heparin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus." [GOC:mah, GOC:yaf] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0061476 ! response to anticoagulant +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-18T03:33:49Z + +[Term] +id: GO:0071504 +name: cellular response to heparin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus." [GOC:mah, GOC:yaf] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0071503 ! response to heparin +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-18T03:34:38Z + +[Term] +id: GO:0071505 +name: response to mycophenolic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus." [GOC:mah, GOC:yaf] +synonym: "response to mycophenolate" EXACT [GOC:mah] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010046 ! response to mycotoxin +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-18T03:46:00Z + +[Term] +id: GO:0071506 +name: cellular response to mycophenolic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus." [GOC:mah, GOC:yaf] +synonym: "cellular response to mycophenolate" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0036146 ! cellular response to mycotoxin +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:0071505 ! response to mycophenolic acid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2009-12-18T03:47:25Z + +[Term] +id: GO:0071507 +name: pheromone response MAPK cascade +namespace: biological_process +def: "A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion." [GOC:mah, GOC:vw, PMID:17604854] +synonym: "conjugation with cellular fusion, MAPKKK cascade" EXACT [GOC:mah] +synonym: "Fus3 signaling cascade" NARROW [PMID:20880736] +synonym: "MAPK cascade involved in conjugation with cellular fusion" EXACT [] +synonym: "MAPK signaling in response to pheromone" RELATED [PMID:20880736] +synonym: "MAPKKK cascade involved in conjugation with cellular fusion" EXACT [GOC:signaling] +synonym: "MAPKKK cascade involved in mating response" RELATED [GOC:mah] +synonym: "pheromone MAPK module" RELATED [PMID:20880736] +is_a: GO:0000165 ! MAPK cascade +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0000165 ! MAPK cascade +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000747 ! conjugation with cellular fusion +relationship: part_of GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +created_by: mah +creation_date: 2010-01-05T01:43:47Z + +[Term] +id: GO:0071508 +name: activation of MAPK activity involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion." [GOC:mah] +synonym: "activation of MAPK activity involved in mating response" RELATED [GOC:mah] +synonym: "conjugation with cellular fusion, activation of MAPK activity" EXACT [GOC:mah] +is_a: GO:0000187 ! activation of MAPK activity +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-01-05T02:09:35Z + +[Term] +id: GO:0071509 +name: activation of MAPKK activity involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion." [GOC:mah] +synonym: "activation of MAP kinase kinase activity during conjugation with cellular fusion" EXACT [GOC:mah] +synonym: "activation of MAPKK activity involved in mating response" RELATED [GOC:mah] +synonym: "conjugation with cellular fusion, activation of MAP kinase kinase activity" EXACT [GOC:mah] +synonym: "conjugation with cellular fusion, activation of MAPKK activity" EXACT [GOC:mah] +is_a: GO:0000186 ! activation of MAPKK activity +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-01-05T02:09:58Z + +[Term] +id: GO:0071510 +name: activation of MAPKKK activity involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion." [GOC:mah] +synonym: "activation of MAP kinase kinase kinase activity during conjugation with cellular fusion" EXACT [GOC:mah] +synonym: "activation of MAPKKK activity involved in mating response" RELATED [GOC:mah] +synonym: "conjugation with cellular fusion, activation of MAP kinase kinase kinase activity" EXACT [GOC:mah] +synonym: "conjugation with cellular fusion, activation of MAPKKK activity" EXACT [GOC:mah] +is_a: GO:0000185 ! activation of MAPKKK activity +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-01-05T02:10:18Z + +[Term] +id: GO:0071511 +name: inactivation of MAPK activity involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion." [GOC:mah] +synonym: "conjugation with cellular fusion, inactivation of MAPK activity" EXACT [GOC:mah] +synonym: "conjugation with cellular fusion, termination of MAPK activity" EXACT [GOC:mah] +synonym: "inactivation of MAPK activity involved in mating response" RELATED [GOC:mah] +synonym: "termination of MAPK activity during conjugation with cellular fusion" EXACT [GOC:mah] +is_a: GO:0000188 ! inactivation of MAPK activity +is_a: GO:0022414 ! reproductive process +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-01-05T02:10:47Z + +[Term] +id: GO:0071512 +name: obsolete MAPK import into nucleus involved in conjugation with cellular fusion +namespace: biological_process +def: "OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion." [GOC:mah] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "conjugation with cellular fusion, MAPK import into nucleus" EXACT [GOC:mah] +synonym: "conjugation with cellular fusion, nuclear translocation of MAPK" NARROW [GOC:mah] +synonym: "MAPK import into nucleus involved in mating response" RELATED [GOC:mah] +synonym: "nuclear translocation of MAPK involved in conjugation with cellular fusion" NARROW [GOC:mah] +synonym: "nuclear translocation of MAPK involved in mating response" RELATED [GOC:mah] +is_obsolete: true +consider: GO:0006606 +created_by: mah +creation_date: 2010-01-05T02:11:08Z + +[Term] +id: GO:0071513 +name: phosphopantothenoylcysteine decarboxylase complex +namespace: cellular_component +def: "A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces." [GOC:jh, PMID:19915539] +comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'. +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2010-01-05T05:23:13Z + +[Term] +id: GO:0071514 +name: genetic imprinting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence." [GOC:mah, GOC:vw] +synonym: "DNA imprinting" EXACT [GOC:mah] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +created_by: mah +creation_date: 2010-01-06T11:56:31Z + +[Term] +id: GO:0071515 +name: genetic imprinting at mating-type locus +namespace: biological_process +def: "A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication." [GOC:mah, PMID:14765111, PMID:18723894] +synonym: "mating type determination, imprinting" EXACT [GOC:vw] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0031494 ! regulation of mating type switching +is_a: GO:0071514 ! genetic imprinting +created_by: mah +creation_date: 2010-01-06T12:58:56Z + +[Term] +id: GO:0071516 +name: establishment of imprinting at mating-type locus +namespace: biological_process +def: "The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication." [GOC:mah, PMID:18723894] +synonym: "mating type determination, establishment of imprinting" EXACT [GOC:vw] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0071515 ! genetic imprinting at mating-type locus +created_by: mah +creation_date: 2010-01-06T01:16:27Z + +[Term] +id: GO:0071517 +name: maintenance of imprinting at mating-type locus +namespace: biological_process +def: "Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication." [GOC:mah, PMID:14765111, PMID:18723894] +synonym: "mating type determination, maintenance of imprinting" EXACT [GOC:mah] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0071515 ! genetic imprinting at mating-type locus +created_by: mah +creation_date: 2010-01-06T01:17:05Z + +[Term] +id: GO:0071518 +name: autoinducer-2 kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP." [GOC:imk, PMID:17274596, PMID:20025244] +synonym: "4,5-dihydroxy-pentane-2,3-dione kinase activity" EXACT [CHEBI:425228, GOC:mah] +xref: MetaCyc:RXN0-5461 +is_a: GO:0016301 ! kinase activity +created_by: mah +creation_date: 2010-01-06T05:08:17Z + +[Term] +id: GO:0071519 +name: actomyosin contractile ring actin filament bundle assembly +namespace: biological_process +def: "A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis." [GOC:mah, PMID:19713940] +synonym: "actin filament bundle assembly involved in actomyosin contractile ring formation" RELATED [GOC:dph, GOC:tb] +synonym: "actin filament bundle assembly involved in cytokinetic actomyosin contractile ring assembly" EXACT [] +is_a: GO:0051017 ! actin filament bundle assembly +is_a: GO:2000689 ! actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0051017 ! actin filament bundle assembly +intersection_of: part_of GO:0000915 ! actomyosin contractile ring assembly +created_by: mah +creation_date: 2010-01-06T05:27:59Z + +[Term] +id: GO:0071520 +name: actomyosin contractile ring assembly actin filament bundle convergence +namespace: biological_process +def: "A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring." [GOC:mah, PMID:19713940] +synonym: "actin filament bundle convergence involved in actomyosin contractile ring formation" RELATED [GOC:dph, GOC:tb] +synonym: "actin filament bundle convergence involved in cytokinetic actomyosin contractile ring assembly" EXACT [] +is_a: GO:0090426 ! actin filament bundle convergence +is_a: GO:2000689 ! actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0090426 ! actin filament bundle convergence +intersection_of: part_of GO:0000915 ! actomyosin contractile ring assembly +created_by: mah +creation_date: 2010-01-06T05:33:16Z + +[Term] +id: GO:0071521 +name: Cdc42 GTPase complex +namespace: cellular_component +def: "A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway." [GOC:mah, GOC:vw, PMID:10567532, PMID:7923372, PMID:8943016] +synonym: "Ras1-Scd1-Scd2-Cdc42-Shk1 complex" EXACT [GOC:vw] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2010-01-07T01:29:12Z + +[Term] +id: GO:0071522 +name: ureidoglycine aminohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3." [MetaCyc:URUR-RXN, PMID:19935661, PMID:20038185] +xref: EC:3.5.3.26 +xref: MetaCyc:URUR-RXN +is_a: GO:0016813 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines +created_by: mah +creation_date: 2010-01-07T01:43:58Z + +[Term] +id: GO:0071523 +name: obsolete TIR domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction." [GOC:amm] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +is_obsolete: true +created_by: mah +creation_date: 2010-01-07T02:11:47Z + +[Term] +id: GO:0071524 +name: pyrrolysine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine." [GOC:dh, PMID:17204561] +synonym: "monomethylamine methyltransferase cofactor lysine adduct biosynthetic process" EXACT [CHEBI:21860] +synonym: "pyrrolysine anabolism" EXACT [GOC:mah] +synonym: "pyrrolysine biosynthesis" EXACT [GOC:mah] +synonym: "pyrrolysine formation" EXACT [GOC:mah] +synonym: "pyrrolysine synthesis" EXACT [GOC:mah] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0071525 ! pyrrolysine metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: mah +creation_date: 2010-01-07T02:40:24Z + +[Term] +id: GO:0071525 +name: pyrrolysine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine." [GOC:mah, PMID:17204561] +synonym: "monomethylamine methyltransferase cofactor lysine adduct metabolic process" EXACT [CHEBI:21860] +synonym: "pyrrolysine metabolism" EXACT [GOC:mah] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: mah +creation_date: 2010-01-07T02:44:49Z + +[Term] +id: GO:0071526 +name: semaphorin-plexin signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand." [GOC:BHF, GOC:mah, GOC:vk, PMID:15239959] +synonym: "semaphorin-plexin signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: mah +creation_date: 2010-01-07T03:48:07Z + +[Term] +id: GO:0071527 +name: semaphorin-plexin signaling pathway involved in outflow tract morphogenesis +namespace: biological_process +def: "A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis." [GOC:BHF, GOC:mah, GOC:vk, PMID:15239959] +synonym: "semaphorin-plexin signalling pathway involved in outflow tract morphogenesis" EXACT [GOC:mah] +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +is_a: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: mah +creation_date: 2010-01-07T03:49:33Z + +[Term] +id: GO:0071528 +name: tRNA re-export from nucleus +namespace: biological_process +def: "The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export." [GOC:mcc, PMID:17475781, PMID:20032305] +synonym: "tRNA reexport from nucleus" EXACT [GOC:mcc] +is_a: GO:0006409 ! tRNA export from nucleus +created_by: mah +creation_date: 2010-01-07T04:17:05Z + +[Term] +id: GO:0071529 +name: cementum mineralization +namespace: biological_process +def: "The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum." [GOC:sl, PMID:17043865] +synonym: "cementum formation" RELATED [GOC:mah] +is_a: GO:0034505 ! tooth mineralization +created_by: mah +creation_date: 2010-01-07T04:18:54Z + +[Term] +id: GO:0071530 +name: obsolete FHA domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction." [GOC:amm, InterPro:IPR000253] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "forkhead-associated domain-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T01:57:36Z + +[Term] +id: GO:0071531 +name: obsolete Rel homology domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction." [GOC:amm, InterPro:IPR011539] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "RHD domain-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T02:16:39Z + +[Term] +id: GO:0071532 +name: ankyrin repeat binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure." [GOC:mah, InterPro:IPR002110] +synonym: "ANK repeat binding" EXACT [GOC:amm] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-01-08T02:21:02Z + +[Term] +id: GO:0071533 +name: obsolete ankyrin repeat-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction." [GOC:amm, InterPro:IPR002110] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "ANK repeat-mediated complex assembly" EXACT [GOC:amm] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T02:27:56Z + +[Term] +id: GO:0071534 +name: obsolete zf-TRAF domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction." [GOC:amm, InterPro:IPR001293] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "TRAF-type zinc finger domain-mediated complex assembly" EXACT [GOC:mah] +synonym: "zinc finger TRAF-type domain-mediated complex assembly" EXACT [GOC:mah] +synonym: "zinc-finger-TRAF domain-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T02:40:50Z + +[Term] +id: GO:0071535 +name: RING-like zinc finger domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain." [GOC:mah, InterPro:IPR014857] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-01-08T03:10:14Z + +[Term] +id: GO:0071536 +name: obsolete RING-like zinc finger domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction." [GOC:amm, InterPro:IPR014857] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "RING-like domain-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T03:19:47Z + +[Term] +id: GO:0071537 +name: obsolete C3HC4-type RING finger domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction." [GOC:amm, InterPro:IPR018957] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "zinc finger C3HC4 type domain-mediated complex assembly" EXACT [GOC:amm] +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T03:42:46Z + +[Term] +id: GO:0071538 +name: obsolete SH2 domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction." [GOC:amm] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +is_obsolete: true +created_by: mah +creation_date: 2010-01-08T03:46:16Z + +[Term] +id: GO:0071539 +name: protein localization to centrosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, the centrosome." [GOC:ecd] +synonym: "protein localisation to centrosome" EXACT [GOC:mah] +is_a: GO:1905508 ! protein localization to microtubule organizing center +created_by: mah +creation_date: 2010-01-12T02:09:45Z + +[Term] +id: GO:0071540 +name: eukaryotic translation initiation factor 3 complex, eIF3e +namespace: cellular_component +def: "An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e." [PMID:15904532, PMID:19061185] +synonym: "eIF3e-containing eukaryotic translation initiation factor 3 complex" EXACT [GOC:mah] +is_a: GO:0005852 ! eukaryotic translation initiation factor 3 complex +created_by: mah +creation_date: 2010-01-12T02:20:24Z + +[Term] +id: GO:0071541 +name: eukaryotic translation initiation factor 3 complex, eIF3m +namespace: cellular_component +def: "An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m." [PMID:15904532, PMID:19061185] +synonym: "eIF3m-containing eukaryotic translation initiation factor 3 complex" EXACT [GOC:mah] +is_a: GO:0005852 ! eukaryotic translation initiation factor 3 complex +created_by: mah +creation_date: 2010-01-12T02:26:41Z + +[Term] +id: GO:0071542 +name: dopaminergic neuron differentiation +namespace: biological_process +def: "The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine." [GOC:rph] +is_a: GO:0030182 ! neuron differentiation +created_by: mah +creation_date: 2010-01-12T02:28:44Z + +[Term] +id: GO:0071543 +name: diphosphoinositol polyphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached." [GOC:mah, PMID:12387729] +synonym: "diphosphoinositol polyphosphate metabolism" EXACT [GOC:mah] +is_a: GO:0043647 ! inositol phosphate metabolic process +created_by: mah +creation_date: 2010-01-12T05:04:00Z + +[Term] +id: GO:0071544 +name: diphosphoinositol polyphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached." [GOC:mah, PMID:12387729] +synonym: "diphosphoinositol polyphosphate breakdown" EXACT [GOC:mah] +synonym: "diphosphoinositol polyphosphate catabolism" EXACT [GOC:mah] +synonym: "diphosphoinositol polyphosphate degradation" EXACT [GOC:mah] +is_a: GO:0071543 ! diphosphoinositol polyphosphate metabolic process +is_a: GO:0071545 ! inositol phosphate catabolic process +created_by: mah +creation_date: 2010-01-12T05:07:10Z + +[Term] +id: GO:0071545 +name: inositol phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached." [GOC:mah] +comment: See also the biological process term 'inositol phosphate dephosphorylation ; GO:0046855'. +synonym: "inositol phosphate breakdown" EXACT [GOC:mah] +synonym: "inositol phosphate catabolism" EXACT [GOC:mah] +synonym: "inositol phosphate degradation" EXACT [GOC:mah] +synonym: "myo-inositol phosphate catabolic process" NARROW [GOC:mah] +is_a: GO:0043647 ! inositol phosphate metabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +created_by: mah +creation_date: 2010-01-12T05:07:45Z + +[Term] +id: GO:0071546 +name: pi-body +namespace: cellular_component +def: "A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes." [GOC:sp, PMID:20011505] +synonym: "intermitochondrial cement" EXACT [GOC:sp] +is_a: GO:0043186 ! P granule +created_by: mah +creation_date: 2010-01-12T05:44:12Z + +[Term] +id: GO:0071547 +name: piP-body +namespace: cellular_component +def: "A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway." [GOC:sp, PMID:20011505] +is_a: GO:0043186 ! P granule +created_by: mah +creation_date: 2010-01-12T05:47:47Z + +[Term] +id: GO:0071548 +name: response to dexamethasone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus." [GOC:mah, GOC:yaf] +synonym: "response to dexamethasone stimulus" EXACT [GOC:dos] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0051384 ! response to glucocorticoid +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: mah +creation_date: 2010-01-13T01:24:40Z + +[Term] +id: GO:0071549 +name: cellular response to dexamethasone stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus." [GOC:mah, GOC:yaf] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071385 ! cellular response to glucocorticoid stimulus +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:0071548 ! response to dexamethasone +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2010-01-13T01:24:49Z + +[Term] +id: GO:0071550 +name: death-inducing signaling complex assembly +namespace: biological_process +def: "A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway." [GOC:amm, GOC:mtg_apoptosis, InterPro:IPR000488] +synonym: "DD-mediated complex assembly" EXACT [GOC:mah] +synonym: "death domain-mediated complex assembly" EXACT [] +synonym: "death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [] +synonym: "death-inducing signaling complex formation" EXACT [] +synonym: "death-inducing signalling complex assembly" EXACT [] +synonym: "DISC assembly" EXACT [] +synonym: "DISC formation" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: mah +creation_date: 2010-01-13T02:48:38Z + +[Term] +id: GO:0071551 +name: RIP homotypic interaction motif binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases." [GOC:mah, PMID:11734559] +synonym: "RHIM binding" EXACT [GOC:mah] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-01-13T03:03:51Z + +[Term] +id: GO:0071552 +name: obsolete RIP homotypic interaction motif-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction." [GOC:amm, PMID:11734559] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "RHIM-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-13T03:08:30Z + +[Term] +id: GO:0071553 +name: G protein-coupled pyrimidinergic nucleotide receptor activity +namespace: molecular_function +def: "Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:sl, PMID:10736418, PMID:12369950, PMID:15796906] +synonym: "G protein coupled pyrimidinergic nucleotide receptor activity" EXACT [] +synonym: "G-protein coupled pyrimidinergic nucleotide receptor activity" EXACT [] +synonym: "pyrimidinergic nucleotide receptor activity, G protein coupled" EXACT [] +synonym: "pyrimidinergic nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0016502 ! nucleotide receptor activity +relationship: has_part GO:0019103 ! pyrimidine nucleotide binding +created_by: mah +creation_date: 2010-01-13T03:13:22Z + +[Term] +id: GO:0071554 +name: cell wall organization or biogenesis +namespace: biological_process +alt_id: GO:0070882 +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall." [GOC:mah] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pombe +subset: goslim_yeast +synonym: "cell wall organisation or biogenesis" EXACT [GOC:mah] +synonym: "cell wall organization or biogenesis at cellular level" EXACT [GOC:mah] +synonym: "cellular cell wall organisation or biogenesis" EXACT [GOC:mah] +synonym: "cellular cell wall organization or biogenesis" EXACT [] +is_a: GO:0009987 ! cellular process +created_by: mah +creation_date: 2010-01-13T03:19:38Z + +[Term] +id: GO:0071555 +name: cell wall organization +namespace: biological_process +alt_id: GO:0007047 +alt_id: GO:0044234 +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:mah] +subset: goslim_candida +subset: goslim_pir +synonym: "cell wall organisation" EXACT [] +synonym: "cell wall organisation in other organism" EXACT [GOC:mah] +synonym: "cell wall organization and biogenesis" RELATED [GOC:mah] +synonym: "cell wall organization at cellular level" EXACT [GOC:mah] +synonym: "cell wall organization in other organism" EXACT [] +synonym: "cellular cell wall organisation" EXACT [] +synonym: "cellular cell wall organization" EXACT [] +is_a: GO:0045229 ! external encapsulating structure organization +is_a: GO:0071554 ! cell wall organization or biogenesis +created_by: mah +creation_date: 2010-01-13T03:33:07Z + +[Term] +id: GO:0071556 +name: integral component of lumenal side of endoplasmic reticulum membrane +namespace: cellular_component +def: "The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to ER membrane, lumenal side" EXACT [GOC:vw] +synonym: "integral to lumenal leaflet of endoplasmic reticulum membrane" EXACT [GOC:ab] +synonym: "integral to lumenal side of endoplasmic reticulum membrane" NARROW [] +synonym: "integral to lumenal side of ER membrane" EXACT [GOC:mah] +is_a: GO:0030176 ! integral component of endoplasmic reticulum membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098553 ! lumenal side of endoplasmic reticulum membrane +relationship: part_of GO:0098553 ! lumenal side of endoplasmic reticulum membrane +created_by: mah +creation_date: 2010-01-15T10:56:58Z + +[Term] +id: GO:0071557 +name: histone H3-K27 demethylation +namespace: biological_process +def: "The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone." [GOC:sp, PMID:20023638] +synonym: "H3K27 demethylation" RELATED [GOC:mah] +is_a: GO:0070076 ! histone lysine demethylation +created_by: mah +creation_date: 2010-01-15T10:59:50Z + +[Term] +id: GO:0071558 +name: histone demethylase activity (H3-K27 specific) +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein." [GOC:sp, PMID:20622853] +xref: EC:1.14.11.68 +xref: Reactome:R-HSA-3222593 "KDM6B demethylates H3K27me3 on p16-INK4A promoter" +xref: Reactome:R-HSA-5617431 "Retinoic acid activates HOXA1 chromatin" +xref: Reactome:R-HSA-5617887 "HOXC4 chromatin is activated" +is_a: GO:0032452 ! histone demethylase activity +relationship: part_of GO:0071557 ! histone H3-K27 demethylation +created_by: mah +creation_date: 2010-01-15T11:33:17Z + +[Term] +id: GO:0071559 +name: response to transforming growth factor beta +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus." [GOC:mah] +synonym: "response to TGF-beta stimulus" EXACT [GOC:mah] +synonym: "response to TGFbeta stimulus" EXACT [GOC:mah] +synonym: "response to transforming growth factor beta stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: mah +creation_date: 2010-01-20T11:49:59Z + +[Term] +id: GO:0071560 +name: cellular response to transforming growth factor beta stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus." [GOC:ecd, PMID:15451575] +synonym: "cellular response to TGF-beta stimulus" EXACT [GOC:mah] +synonym: "cellular response to TGFbeta stimulus" EXACT [GOC:mah] +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:0071559 ! response to transforming growth factor beta +created_by: mah +creation_date: 2010-01-20T11:51:18Z + +[Term] +id: GO:0071561 +name: nucleus-vacuole junction +namespace: cellular_component +def: "An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p." [GOC:jp, PMID:16709156, PMID:16806880] +synonym: "nucleus-vacuole membrane contact site" EXACT [GOC:mah] +synonym: "NV junction" EXACT [GOC:jp, PMID:16709156] +synonym: "NVJ" EXACT [GOC:mah, PMID:16806880] +is_a: GO:0044232 ! organelle membrane contact site +created_by: mah +creation_date: 2010-01-20T02:09:42Z + +[Term] +id: GO:0071562 +name: nucleus-vacuole junction assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p." [GOC:jp, PMID:16709156] +synonym: "nucleus-vacuole junction formation" EXACT [GOC:jp] +synonym: "NV junction assembly" EXACT [GOC:jp, PMID:16709156] +synonym: "NV junction formation" EXACT [GOC:jp, PMID:16709156] +synonym: "NVJ assembly" EXACT [GOC:mah, PMID:16806880] +synonym: "NVJ formation" EXACT [GOC:mah, PMID:16806880] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0140056 ! organelle localization by membrane tethering +relationship: part_of GO:0034727 ! piecemeal microautophagy of the nucleus +created_by: mah +creation_date: 2010-01-20T02:16:36Z + +[Term] +id: GO:0071563 +name: Myo2p-Vac17p-Vac8p transport complex +namespace: cellular_component +def: "A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p." [GOC:jp, PMID:12594460] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2010-01-20T03:03:24Z + +[Term] +id: GO:0071564 +name: npBAF complex +namespace: cellular_component +def: "A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells." [GOC:mah, GOC:ss, PMID:17640523] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: mah +creation_date: 2010-01-20T03:33:42Z + +[Term] +id: GO:0071565 +name: nBAF complex +namespace: cellular_component +def: "A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth." [GOC:mah, GOC:ss, PMID:17640523] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: mah +creation_date: 2010-01-20T03:41:19Z + +[Term] +id: GO:0071566 +name: UFM1 activating enzyme activity +namespace: molecular_function +def: "Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:sp, PMID:20018847] +is_a: GO:0008641 ! ubiquitin-like modifier activating enzyme activity +created_by: mah +creation_date: 2010-01-20T04:06:05Z + +[Term] +id: GO:0071567 +name: UFM1 hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates." [GOC:sp, PMID:20018847] +is_a: GO:0019783 ! ubiquitin-like protein-specific protease activity +created_by: mah +creation_date: 2010-01-20T04:08:34Z + +[Term] +id: GO:0071568 +name: UFM1 transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages." [GOC:sp, PMID:20018847] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +created_by: mah +creation_date: 2010-01-20T04:10:11Z + +[Term] +id: GO:0071569 +name: protein ufmylation +namespace: biological_process +def: "Covalent attachment of the ubiquitin-like protein UFM1 to another protein." [GOC:vw, PMID:20018847] +is_a: GO:0032446 ! protein modification by small protein conjugation +created_by: mah +creation_date: 2010-01-20T04:12:01Z + +[Term] +id: GO:0071570 +name: cement gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed." [GOC:bf] +is_a: GO:0048732 ! gland development +created_by: mah +creation_date: 2010-01-20T04:31:04Z + +[Term] +id: GO:0071571 +name: obsolete LRR domain-mediated complex assembly +namespace: biological_process +def: "OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction." [GOC:amm, InterPro:IPR001611] +comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex. +synonym: "leucine-rich repeat domain-mediated complex assembly" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-01-20T04:33:49Z + +[Term] +id: GO:0071572 +name: histone H3-K56 deacetylation +namespace: biological_process +def: "The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone." [GOC:mah] +is_a: GO:0070932 ! histone H3 deacetylation +created_by: mah +creation_date: 2010-01-20T04:50:03Z + +[Term] +id: GO:0071573 +name: shelterin complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase." [GOC:mah, GOC:vw] +synonym: "Pot1 complex assembly" RELATED [GOC:mah, GOC:vw] +synonym: "Pot1-Tpz1 complex assembly" RELATED [GIOC:vw, GOC:mah] +synonym: "shelterin complex formation" RELATED [GOC:mah, GOC:vw] +synonym: "telosome assembly" EXACT [] +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0032200 ! telomere organization +created_by: mah +creation_date: 2010-01-26T01:45:20Z + +[Term] +id: GO:0071574 +name: protein localization to medial cortex +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the medial cortex." [GOC:mah] +synonym: "protein localisation to medial cortex" EXACT [GOC:mah] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:0072741 ! protein localization to cell division site +created_by: mah +creation_date: 2010-01-26T05:17:50Z + +[Term] +id: GO:0071575 +name: integral component of external side of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to external leaflet of plasma membrane" EXACT [GOC:ab] +synonym: "integral to external side of plasma membrane" NARROW [] +is_a: GO:0005887 ! integral component of plasma membrane +is_a: GO:0031233 ! intrinsic component of external side of plasma membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009897 ! external side of plasma membrane +created_by: mah +creation_date: 2010-01-26T05:20:28Z + +[Term] +id: GO:0071576 +name: tetrahydrodictyopterin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one." [GOC:mah, GOC:vw] +synonym: "D-threo-tetrahydrobiopterin" EXACT [GOC:mah] +synonym: "DH4 binding" EXACT [GOC:mah] +is_a: GO:0034617 ! tetrahydrobiopterin binding +created_by: mah +creation_date: 2010-01-26T05:24:59Z + +[Term] +id: GO:0071577 +name: zinc ion transmembrane transport +namespace: biological_process +def: "A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "zinc II ion transmembrane transport" EXACT [] +synonym: "zinc ion membrane transport" EXACT [] +synonym: "zinc transmembrane transport" EXACT [GOC:mah] +is_a: GO:0006829 ! zinc ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2010-01-28T02:17:12Z + +[Term] +id: GO:0071578 +name: zinc ion import across plasma membrane +namespace: biological_process +alt_id: GO:0006830 +alt_id: GO:0006831 +alt_id: GO:0044749 +alt_id: GO:0140160 +def: "The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw, PMID:18637840] +synonym: "high-affinity zinc II ion transmembrane import" NARROW [] +synonym: "high-affinity zinc II ion transport" NARROW [] +synonym: "low-affinity zinc II ion transport" NARROW [] +synonym: "zinc II ion plasma membrane import" EXACT [] +synonym: "zinc II ion transmembrane import" EXACT [] +synonym: "zinc import" EXACT [GOC:mah] +synonym: "zinc ion transmembrane import" RELATED [] +synonym: "zinc uptake" EXACT [GOC:mah] +is_a: GO:0071577 ! zinc ion transmembrane transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: jl +creation_date: 2010-01-28T02:22:02Z + +[Term] +id: GO:0071579 +name: regulation of zinc ion transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah] +is_a: GO:0010959 ! regulation of metal ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006829 ! zinc ion transport +relationship: regulates GO:0006829 ! zinc ion transport +created_by: mah +creation_date: 2010-01-28T03:02:15Z + +[Term] +id: GO:0071580 +name: regulation of zinc ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other." [GOC:BHF, GOC:mah] +synonym: "regulation of zinc ion membrane transport" EXACT [] +is_a: GO:0071579 ! regulation of zinc ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071577 ! zinc ion transmembrane transport +relationship: regulates GO:0071577 ! zinc ion transmembrane transport +created_by: mah +creation_date: 2010-01-28T03:05:53Z + +[Term] +id: GO:0071581 +name: regulation of zinc ion transmembrane import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of zinc ion import." [GOC:BHF, GOC:mah] +is_a: GO:0071580 ! regulation of zinc ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071578 ! zinc ion import across plasma membrane +relationship: regulates GO:0071578 ! zinc ion import across plasma membrane +created_by: mah +creation_date: 2010-01-28T03:09:19Z + +[Term] +id: GO:0071582 +name: negative regulation of zinc ion transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0071579 ! regulation of zinc ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006829 ! zinc ion transport +relationship: negatively_regulates GO:0006829 ! zinc ion transport +created_by: mah +creation_date: 2010-01-28T03:14:25Z + +[Term] +id: GO:0071583 +name: negative regulation of zinc ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other." [GOC:BHF, GOC:mah] +synonym: "negative regulation of zinc ion membrane transport" EXACT [] +is_a: GO:0071580 ! regulation of zinc ion transmembrane transport +is_a: GO:0071582 ! negative regulation of zinc ion transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071577 ! zinc ion transmembrane transport +relationship: negatively_regulates GO:0071577 ! zinc ion transmembrane transport +created_by: mah +creation_date: 2010-01-28T03:15:54Z + +[Term] +id: GO:0071584 +name: negative regulation of zinc ion transmembrane import +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import." [GOC:BHF, GOC:mah] +is_a: GO:0071581 ! regulation of zinc ion transmembrane import +is_a: GO:0071583 ! negative regulation of zinc ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071578 ! zinc ion import across plasma membrane +relationship: negatively_regulates GO:0071578 ! zinc ion import across plasma membrane +created_by: mah +creation_date: 2010-01-28T03:17:21Z + +[Term] +id: GO:0071585 +name: detoxification of cadmium ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion." [GOC:BHF, GOC:kmv, PMID:16741752] +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:1990170 ! stress response to cadmium ion +created_by: mah +creation_date: 2010-01-28T03:38:48Z + +[Term] +id: GO:0071586 +name: CAAX-box protein processing +namespace: biological_process +def: "The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis." [GOC:mah] +is_a: GO:0016485 ! protein processing +relationship: part_of GO:0080120 ! CAAX-box protein maturation +created_by: mah +creation_date: 2010-01-28T04:42:45Z + +[Term] +id: GO:0071587 +name: CAAX-box protein modification +namespace: biological_process +def: "The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins." [GOC:mah] +is_a: GO:0043687 ! post-translational protein modification +relationship: part_of GO:0080120 ! CAAX-box protein maturation +created_by: mah +creation_date: 2010-01-28T04:48:56Z + +[Term] +id: GO:0071588 +name: hydrogen peroxide mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2)." [GOC:mah, PMID:17043891] +synonym: "H2O2 mediated signaling pathway" EXACT [GOC:mah] +synonym: "hydrogen peroxide mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0007165 ! signal transduction +created_by: mah +creation_date: 2010-01-29T11:18:58Z + +[Term] +id: GO:0071589 +name: pyridine nucleoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose." [GOC:mah] +synonym: "pyridine nucleoside anabolism" EXACT [GOC:mah] +synonym: "pyridine nucleoside biosynthesis" EXACT [GOC:mah] +synonym: "pyridine nucleoside formation" EXACT [GOC:mah] +synonym: "pyridine nucleoside synthesis" EXACT [GOC:mah] +is_a: GO:0009163 ! nucleoside biosynthetic process +is_a: GO:0070637 ! pyridine nucleoside metabolic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process +created_by: mah +creation_date: 2010-01-29T11:35:30Z + +[Term] +id: GO:0071590 +name: nicotinamide riboside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide." [GOC:mah, PMID:19846558] +synonym: "N-ribosylnicotinamide biosynthetic process" EXACT [CHEBI:15927] +synonym: "nicotinamide riboside anabolism" EXACT [GOC:mah] +synonym: "nicotinamide riboside biosynthesis" EXACT [GOC:mah] +synonym: "nicotinamide riboside formation" EXACT [GOC:mah] +synonym: "nicotinamide riboside synthesis" EXACT [GOC:mah] +is_a: GO:0046495 ! nicotinamide riboside metabolic process +is_a: GO:0071589 ! pyridine nucleoside biosynthetic process +created_by: mah +creation_date: 2010-01-29T11:39:27Z + +[Term] +id: GO:0071591 +name: nicotinic acid riboside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid." [GOC:mah, PMID:19846558] +synonym: "D-ribosylnicotinic acid metabolic process" EXACT [CHEBI:27748] +synonym: "nicotinic acid riboside metabolism" EXACT [GOC:mah] +is_a: GO:0070637 ! pyridine nucleoside metabolic process +created_by: mah +creation_date: 2010-01-29T11:50:42Z + +[Term] +id: GO:0071592 +name: nicotinic acid riboside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid." [GOC:mah, PMID:19846558] +synonym: "D-ribosylnicotinic acid biosynthetic process" EXACT [CHEBI:27748] +synonym: "nicotinic acid riboside anabolism" EXACT [GOC:mah] +synonym: "nicotinic acid riboside biosynthesis" EXACT [GOC:mah] +synonym: "nicotinic acid riboside formation" EXACT [GOC:mah] +synonym: "nicotinic acid riboside synthesis" EXACT [GOC:mah] +is_a: GO:0071589 ! pyridine nucleoside biosynthetic process +is_a: GO:0071591 ! nicotinic acid riboside metabolic process +created_by: mah +creation_date: 2010-01-29T12:01:25Z + +[Term] +id: GO:0071593 +name: lymphocyte aggregation +namespace: biological_process +def: "The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules." [GOC:sl] +is_a: GO:0070486 ! leukocyte aggregation +created_by: mah +creation_date: 2010-01-29T01:37:30Z + +[Term] +id: GO:0071594 +name: thymocyte aggregation +namespace: biological_process +def: "The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules." [GOC:sl, PMID:1382990] +synonym: "immature T cell aggregation" BROAD [CL:0000893, GOC:sl] +synonym: "immature T-cell aggregation" BROAD [CL:0000893, GOC:mah] +synonym: "immature T-lymphocyte aggregation" EXACT [CL:0000893, GOC:mah] +synonym: "T cell precursor aggregation" EXACT [GOC:sl] +synonym: "thymic lymphocyte aggregation" EXACT [GOC:sl] +is_a: GO:0070489 ! T cell aggregation +created_by: mah +creation_date: 2010-01-29T01:38:49Z + +[Term] +id: GO:0071595 +name: Nem1-Spo7 phosphatase complex +namespace: cellular_component +def: "A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p." [GOC:mah, PMID:9822591] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network +created_by: mah +creation_date: 2010-01-29T02:17:29Z + +[Term] +id: GO:0071596 +name: ubiquitin-dependent protein catabolic process via the N-end rule pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation." [GOC:mah, GOC:rb, PMID:19246002, PMID:9112437] +synonym: "ubiquitin-dependent protein breakdown via the N-end rule pathway" EXACT [GOC:mah] +synonym: "ubiquitin-dependent protein catabolism via the N-end rule pathway" EXACT [GOC:mah] +synonym: "ubiquitin-dependent protein degradation via the N-end rule pathway" EXACT [GOC:mah] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +created_by: mah +creation_date: 2010-01-29T03:01:09Z + +[Term] +id: GO:0071597 +name: cellular birth scar +namespace: cellular_component +def: "Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation." [GOC:mcc, PMID:16672383, PMID:7730409] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009277 ! fungal-type cell wall +created_by: mah +creation_date: 2010-02-02T02:42:44Z + +[Term] +id: GO:0071598 +name: neuronal ribonucleoprotein granule +namespace: cellular_component +def: "A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli." [GOC:BHF, GOC:go_curators, GOC:mah, PMID:19015237, PMID:20368989] +synonym: "neuronal RNA granule" NARROW [] +synonym: "neuronal RNP granule" EXACT [] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +relationship: part_of GO:0120111 ! neuron projection cytoplasm +created_by: mah +creation_date: 2010-02-04T04:01:57Z + +[Term] +id: GO:0071599 +name: otic vesicle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] +is_a: GO:0007423 ! sensory organ development +is_a: GO:0035295 ! tube development +is_a: GO:0048839 ! inner ear development +is_a: GO:0060429 ! epithelium development +created_by: mah +creation_date: 2010-02-04T04:07:17Z + +[Term] +id: GO:0071600 +name: otic vesicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] +is_a: GO:0042472 ! inner ear morphogenesis +is_a: GO:0048562 ! embryonic organ morphogenesis +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0071599 ! otic vesicle development +created_by: mah +creation_date: 2010-02-04T04:07:27Z + +[Term] +id: GO:0071601 +name: sphere organelle +namespace: cellular_component +def: "A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins." [PMID:7758244, PMID:8349728] +is_a: GO:0016604 ! nuclear body +created_by: mah +creation_date: 2010-02-04T04:26:41Z + +[Term] +id: GO:0071602 +name: phytosphingosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol." [GOC:mah] +synonym: "phytosphingosine anabolism" EXACT [GOC:mah] +synonym: "phytosphingosine biosynthesis" EXACT [GOC:mah] +synonym: "phytosphingosine formation" EXACT [GOC:mah] +synonym: "phytosphingosine synthesis" EXACT [GOC:mah] +is_a: GO:0006671 ! phytosphingosine metabolic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0046520 ! sphingoid biosynthetic process +created_by: mah +creation_date: 2010-02-04T05:15:59Z + +[Term] +id: GO:0071603 +name: endothelial cell-cell adhesion +namespace: biological_process +def: "The attachment of an endothelial cell to another endothelial cell via adhesion molecules." [GOC:BHF] +is_a: GO:0090136 ! epithelial cell-cell adhesion +created_by: mah +creation_date: 2010-02-04T05:21:30Z + +[Term] +id: GO:0071604 +name: transforming growth factor beta production +namespace: biological_process +def: "The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3." [GOC:add, GOC:rv] +synonym: "TGF-B production" EXACT [GOC:mah] +synonym: "TGF-beta production" EXACT [GOC:mah] +synonym: "TGFB production" EXACT [GOC:mah] +synonym: "TGFb production" EXACT [GOC:rv] +synonym: "transforming growth factor-beta production" EXACT [GOC:bf] +is_a: GO:0001816 ! cytokine production +created_by: mah +creation_date: 2010-02-05T03:56:57Z + +[Term] +id: GO:0071605 +name: monocyte chemotactic protein-1 production +namespace: biological_process +def: "The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL2 production" EXACT [GOC:add, GOC:rv] +synonym: "MCP-1 production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:09:53Z + +[Term] +id: GO:0071606 +name: chemokine (C-C motif) ligand 4 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL4 production" EXACT [GOC:add, GOC:rv] +synonym: "macrophage inflammatory protein production" BROAD [GOC:add, GOC:rv] +synonym: "MIP-1b production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:16:42Z + +[Term] +id: GO:0071607 +name: macrophage inflammatory protein-1 gamma production +namespace: biological_process +def: "The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL9 production" EXACT [GOC:add, GOC:rv] +synonym: "chemokine (C-C motif) ligand 9 production" EXACT [GOC:add, GOC:rv] +synonym: "MIP-1g production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:19:52Z + +[Term] +id: GO:0071608 +name: macrophage inflammatory protein-1 alpha production +namespace: biological_process +def: "The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL3 production" EXACT [GOC:add, GOC:rv] +synonym: "chemokine (C-C motif) ligand 3 production" EXACT [GOC:add, GOC:rv] +synonym: "macrophage inflammatory protein production" BROAD [GOC:add, GOC:rv] +synonym: "MIP-1a production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:24:17Z + +[Term] +id: GO:0071609 +name: chemokine (C-C motif) ligand 5 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL5 production" EXACT [GOC:add, GOC:rv] +synonym: "RANTES production" EXACT [GOC:bf] +synonym: "Regulated upon Activation, Normal T-cell Expressed, and Secreted production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:32:35Z + +[Term] +id: GO:0071610 +name: chemokine (C-C motif) ligand 1 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "CCL1 production" EXACT [GOC:add, GOC:rv] +synonym: "T cell activation 3 production" EXACT [GOC:add, GOC:rv] +synonym: "TCA-3 production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:35:00Z + +[Term] +id: GO:0071611 +name: granulocyte colony-stimulating factor production +namespace: biological_process +def: "The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "colony stimulating factor 3 (granulocyte) production" EXACT [GOC:add] +synonym: "CSF3 production" EXACT [GOC:add] +synonym: "filgrastim production" EXACT [GOC:add] +synonym: "G-CSF production" EXACT [GOC:add] +synonym: "granulocyte colony stimulating factor production" EXACT [] +synonym: "lenograstim production" EXACT [GOC:add] +synonym: "pluripoietin production" EXACT [GOC:add] +is_a: GO:0001816 ! cytokine production +created_by: mah +creation_date: 2010-02-05T04:38:11Z + +[Term] +id: GO:0071612 +name: IP-10 production +namespace: biological_process +def: "The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +synonym: "chemokine (C-C motif) ligand 10 production" EXACT [GOC:add, GOC:rv] +synonym: "CXCL10 production" EXACT [GOC:add, GOC:rv] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-02-05T04:43:56Z + +[Term] +id: GO:0071613 +name: granzyme B production +namespace: biological_process +def: "The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:rv] +is_a: GO:0002440 ! production of molecular mediator of immune response +created_by: mah +creation_date: 2010-02-05T04:47:15Z + +[Term] +id: GO:0071614 +name: linoleic acid epoxygenase activity +namespace: molecular_function +def: "Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid." [GOC:BHF, PMID:11042099] +synonym: "linoleic acid monooxygenase activity" EXACT [GOC:mah] +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: mah +creation_date: 2010-02-05T06:05:22Z + +[Term] +id: GO:0071615 +name: oxidative deethylation +namespace: biological_process +def: "The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate." [GOC:BHF, GOC:mah, GOC:rl] +is_a: GO:0055114 ! oxidation-reduction process +created_by: mah +creation_date: 2010-02-05T06:11:41Z + +[Term] +id: GO:0071616 +name: acyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group." [GOC:cjk] +synonym: "acyl-CoA anabolism" EXACT [GOC:mah] +synonym: "acyl-CoA biosynthesis" EXACT [GOC:mah] +synonym: "acyl-CoA formation" EXACT [GOC:mah] +synonym: "acyl-CoA synthesis" EXACT [GOC:mah] +is_a: GO:0006637 ! acyl-CoA metabolic process +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0034030 ! ribonucleoside bisphosphate biosynthetic process +is_a: GO:0034033 ! purine nucleoside bisphosphate biosynthetic process +is_a: GO:0035384 ! thioester biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +created_by: mah +creation_date: 2010-02-08T04:43:31Z + +[Term] +id: GO:0071617 +name: lysophospholipid acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid." [GOC:cjk] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: mah +creation_date: 2010-02-08T04:53:37Z + +[Term] +id: GO:0071618 +name: lysophosphatidylethanolamine acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine." [GOC:cjk] +is_a: GO:0071617 ! lysophospholipid acyltransferase activity +created_by: mah +creation_date: 2010-02-08T04:59:07Z + +[Term] +id: GO:0071619 +name: phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +namespace: biological_process +def: "The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans." [GOC:krc, PMID:17079683] +is_a: GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +created_by: mah +creation_date: 2010-02-09T02:37:02Z + +[Term] +id: GO:0071620 +name: phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +namespace: biological_process +def: "The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans)." [GOC:krc, PMID:17079683] +is_a: GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +created_by: mah +creation_date: 2010-02-09T02:39:52Z + +[Term] +id: GO:0071621 +name: granulocyte chemotaxis +namespace: biological_process +def: "The movement of a granulocyte in response to an external stimulus." [GOC:rph] +is_a: GO:0030595 ! leukocyte chemotaxis +is_a: GO:0097530 ! granulocyte migration +created_by: mah +creation_date: 2010-02-09T04:08:17Z + +[Term] +id: GO:0071622 +name: regulation of granulocyte chemotaxis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." [GOC:mah] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071621 ! granulocyte chemotaxis +relationship: regulates GO:0071621 ! granulocyte chemotaxis +created_by: mah +creation_date: 2010-02-09T04:09:24Z + +[Term] +id: GO:0071623 +name: negative regulation of granulocyte chemotaxis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." [GOC:mah] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:0071622 ! regulation of granulocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071621 ! granulocyte chemotaxis +relationship: negatively_regulates GO:0071621 ! granulocyte chemotaxis +created_by: mah +creation_date: 2010-02-09T04:13:19Z + +[Term] +id: GO:0071624 +name: positive regulation of granulocyte chemotaxis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus." [GOC:mah] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:0071622 ! regulation of granulocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071621 ! granulocyte chemotaxis +relationship: positively_regulates GO:0071621 ! granulocyte chemotaxis +created_by: mah +creation_date: 2010-02-09T04:15:36Z + +[Term] +id: GO:0071625 +name: vocalization behavior +namespace: biological_process +def: "The behavior in which an organism produces sounds by a mechanism involving its respiratory system." [GOC:mah] +synonym: "vocalisation behaviour" EXACT [GOC:mah] +is_a: GO:0007610 ! behavior +created_by: mah +creation_date: 2010-02-10T11:02:58Z + +[Term] +id: GO:0071626 +name: mastication +namespace: biological_process +def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg] +synonym: "chewing" EXACT [GOC:mah] +is_a: GO:0022600 ! digestive system process +created_by: mah +creation_date: 2010-02-10T11:19:48Z + +[Term] +id: GO:0071627 +name: integral component of fungal-type vacuolar membrane +namespace: cellular_component +def: "The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:mah] +synonym: "integral to fungal-type vacuolar membrane" NARROW [] +is_a: GO:0031166 ! integral component of vacuolar membrane +is_a: GO:0071628 ! intrinsic component of fungal-type vacuolar membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0000329 ! fungal-type vacuole membrane +created_by: mah +creation_date: 2010-02-10T03:45:23Z + +[Term] +id: GO:0071628 +name: intrinsic component of fungal-type vacuolar membrane +namespace: cellular_component +def: "The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +is_a: GO:0031310 ! intrinsic component of vacuolar membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0000329 ! fungal-type vacuole membrane +relationship: part_of GO:0000329 ! fungal-type vacuole membrane +created_by: mah +creation_date: 2010-02-10T03:53:00Z + +[Term] +id: GO:0071629 +name: cytoplasm protein quality control by the ubiquitin-proteasome system +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation." [GOC:mah, GOC:rb, PMID:20080635] +comment: See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'. +synonym: "cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown" EXACT [GOC:mah] +synonym: "cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism" EXACT [GOC:mah] +synonym: "cytoplasm-associated proteasomal ubiquitin-dependent protein degradation" EXACT [GOC:mah] +synonym: "ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome" EXACT [] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +is_a: GO:0140455 ! cytoplasm protein quality control +relationship: part_of GO:0071218 ! cellular response to misfolded protein +created_by: mah +creation_date: 2010-02-11T03:06:57Z + +[Term] +id: GO:0071630 +name: nuclear protein quality control by the ubiquitin-proteasome system +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation." [GOC:mah, GOC:rb, PMID:20080635, PMID:21211726, PMID:21324894] +comment: See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'. +synonym: "nucleus-associated proteasomal ubiquitin-dependent protein breakdown" EXACT [GOC:mah] +synonym: "nucleus-associated proteasomal ubiquitin-dependent protein catabolism" EXACT [GOC:mah] +synonym: "nucleus-associated proteasomal ubiquitin-dependent protein degradation" EXACT [GOC:mah] +synonym: "ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome" EXACT [] +is_a: GO:0006515 ! protein quality control for misfolded or incompletely synthesized proteins +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +relationship: part_of GO:0071218 ! cellular response to misfolded protein +created_by: mah +creation_date: 2010-02-11T03:31:46Z + +[Term] +id: GO:0071631 +name: mating pheromone secretion involved in positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types." [GOC:elh, GOC:jh, GOC:mah] +synonym: "mating-type pheromone secretion involved in conjugation with cellular fusion" EXACT [GOC:vw] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +is_a: GO:0071834 ! mating pheromone secretion +intersection_of: GO:0071834 ! mating pheromone secretion +intersection_of: positively_regulates GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-02-11T03:36:57Z + +[Term] +id: GO:0071632 +name: optomotor response +namespace: biological_process +def: "Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish." [GOC:dos, PMID:12726833, PMID:2469195] +xref: Wikipedia:Optomotor_response +is_a: GO:0007634 ! optokinetic behavior +created_by: mah +creation_date: 2010-02-11T04:06:41Z + +[Term] +id: GO:0071633 +name: dihydroceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine." [GOC:mah, PMID:10900202] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +is_a: GO:0017040 ! N-acylsphingosine amidohydrolase activity +created_by: mah +creation_date: 2010-02-11T04:24:12Z + +[Term] +id: GO:0071634 +name: regulation of transforming growth factor beta production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta." [GOC:mah] +synonym: "regulation of TGF-B production" EXACT [GOC:mah] +synonym: "regulation of TGF-beta production" EXACT [GOC:mah] +synonym: "regulation of TGFB production" EXACT [GOC:mah] +synonym: "regulation of transforming growth factor-beta production" EXACT [GOC:bf] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071604 ! transforming growth factor beta production +relationship: regulates GO:0071604 ! transforming growth factor beta production +created_by: mah +creation_date: 2010-02-12T10:33:07Z + +[Term] +id: GO:0071635 +name: negative regulation of transforming growth factor beta production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta." [GOC:mah] +synonym: "negative regulation of TGF-B production" EXACT [GOC:mah] +synonym: "negative regulation of TGF-beta production" EXACT [GOC:mah] +synonym: "negative regulation of TGFB production" EXACT [GOC:mah] +synonym: "negative regulation of transforming growth factor-beta production" EXACT [GOC:bf] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071604 ! transforming growth factor beta production +relationship: negatively_regulates GO:0071604 ! transforming growth factor beta production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071636 +name: positive regulation of transforming growth factor beta production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta." [GOC:mah] +synonym: "positive regulation of TGF-B production" EXACT [GOC:mah] +synonym: "positive regulation of TGF-beta production" EXACT [GOC:mah] +synonym: "positive regulation of TGFB production" EXACT [GOC:mah] +synonym: "positive regulation of transforming growth factor-beta production" EXACT [GOC:bf] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071604 ! transforming growth factor beta production +relationship: positively_regulates GO:0071604 ! transforming growth factor beta production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071637 +name: regulation of monocyte chemotactic protein-1 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1." [GOC:mah] +synonym: "regulation of CCL2 production" EXACT [GOC:mah] +synonym: "regulation of MCP-1 production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071605 ! monocyte chemotactic protein-1 production +relationship: regulates GO:0071605 ! monocyte chemotactic protein-1 production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071638 +name: negative regulation of monocyte chemotactic protein-1 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1." [GOC:mah] +synonym: "negative regulation of CCL2 production" EXACT [GOC:mah] +synonym: "negative regulation of MCP-1 production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071637 ! regulation of monocyte chemotactic protein-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071605 ! monocyte chemotactic protein-1 production +relationship: negatively_regulates GO:0071605 ! monocyte chemotactic protein-1 production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071639 +name: positive regulation of monocyte chemotactic protein-1 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1." [GOC:mah] +synonym: "positive regulation of CCL2 production" EXACT [GOC:mah] +synonym: "positive regulation of MCP-1 production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071637 ! regulation of monocyte chemotactic protein-1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071605 ! monocyte chemotactic protein-1 production +relationship: positively_regulates GO:0071605 ! monocyte chemotactic protein-1 production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071640 +name: regulation of macrophage inflammatory protein 1 alpha production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha." [GOC:mah] +synonym: "regulation of CCL3 production" EXACT [GOC:mah] +synonym: "regulation of chemokine (C-C motif) ligand 3 production" EXACT [GOC:mah] +synonym: "regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "regulation of MIP-1a production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +relationship: regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071641 +name: negative regulation of macrophage inflammatory protein 1 alpha production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha." [GOC:mah] +synonym: "negative regulation of CCL3 production" EXACT [GOC:mah] +synonym: "negative regulation of chemokine (C-C motif) ligand 3 production" EXACT [GOC:mah] +synonym: "negative regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "negative regulation of MIP-1a production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071640 ! regulation of macrophage inflammatory protein 1 alpha production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +relationship: negatively_regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071642 +name: positive regulation of macrophage inflammatory protein 1 alpha production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha." [GOC:mah] +synonym: "positive regulation of CCL3 production" EXACT [GOC:mah] +synonym: "positive regulation of chemokine (C-C motif) ligand 3 production" EXACT [GOC:mah] +synonym: "positive regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "positive regulation of MIP-1a production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071640 ! regulation of macrophage inflammatory protein 1 alpha production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +relationship: positively_regulates GO:0071608 ! macrophage inflammatory protein-1 alpha production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071643 +name: regulation of chemokine (C-C motif) ligand 4 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4." [GOC:mah] +synonym: "regulation of CCL4 production" EXACT [GOC:mah] +synonym: "regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "regulation of MIP-1b production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +relationship: regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +created_by: mah +creation_date: 2010-02-12T10:39:51Z + +[Term] +id: GO:0071644 +name: negative regulation of chemokine (C-C motif) ligand 4 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4." [GOC:mah] +synonym: "negative regulation of CCL4 production" EXACT [GOC:mah] +synonym: "negative regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "negative regulation of MIP-1b production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071643 ! regulation of chemokine (C-C motif) ligand 4 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +relationship: negatively_regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071645 +name: positive regulation of chemokine (C-C motif) ligand 4 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4." [GOC:mah] +synonym: "positive regulation of CCL4 production" EXACT [GOC:mah] +synonym: "positive regulation of macrophage inflammatory protein production" BROAD [GOC:mah] +synonym: "positive regulation of MIP-1b production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071643 ! regulation of chemokine (C-C motif) ligand 4 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +relationship: positively_regulates GO:0071606 ! chemokine (C-C motif) ligand 4 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071646 +name: regulation of macrophage inflammatory protein-1 gamma production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma." [GOC:mah] +synonym: "regulation of CCL9 production" EXACT [GOC:mah] +synonym: "regulation of chemokine (C-C motif) ligand 9 production" EXACT [GOC:mah] +synonym: "regulation of MIP-1g production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +relationship: regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071647 +name: negative regulation of macrophage inflammatory protein-1 gamma production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma." [GOC:mah] +synonym: "negative regulation of CCL9 production" EXACT [GOC:mah] +synonym: "negative regulation of chemokine (C-C motif) ligand 9 production" EXACT [GOC:mah] +synonym: "negative regulation of MIP-1g production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071646 ! regulation of macrophage inflammatory protein-1 gamma production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +relationship: negatively_regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071648 +name: positive regulation of macrophage inflammatory protein-1 gamma production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma." [GOC:mah] +synonym: "positive regulation of CCL9 production" EXACT [GOC:mah] +synonym: "positive regulation of chemokine (C-C motif) ligand 9 production" EXACT [GOC:mah] +synonym: "positive regulation of MIP-1g production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071646 ! regulation of macrophage inflammatory protein-1 gamma production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +relationship: positively_regulates GO:0071607 ! macrophage inflammatory protein-1 gamma production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071649 +name: regulation of chemokine (C-C motif) ligand 5 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5." [GOC:mah] +synonym: "regulation of CCL5 production" EXACT [GOC:mah] +synonym: "regulation of RANTES production" EXACT [GOC:bf] +synonym: "regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +relationship: regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071650 +name: negative regulation of chemokine (C-C motif) ligand 5 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5." [GOC:mah] +synonym: "negative regulation of CCL5 production" EXACT [GOC:mah] +synonym: "negative regulation of RANTES production" EXACT [GOC:bf] +synonym: "negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071649 ! regulation of chemokine (C-C motif) ligand 5 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +relationship: negatively_regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071651 +name: positive regulation of chemokine (C-C motif) ligand 5 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5." [GOC:mah] +synonym: "positive regulation of CCL5 production" EXACT [GOC:mah] +synonym: "positive regulation of RANTES production" EXACT [GOC:bf] +synonym: "positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071649 ! regulation of chemokine (C-C motif) ligand 5 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +relationship: positively_regulates GO:0071609 ! chemokine (C-C motif) ligand 5 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071652 +name: regulation of chemokine (C-C motif) ligand 1 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1." [GOC:mah] +synonym: "regulation of CCL1 production" EXACT [GOC:mah] +synonym: "regulation of T cell activation 3 production" EXACT [GOC:mah] +synonym: "regulation of TCA-3 production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +relationship: regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +created_by: mah +creation_date: 2010-02-12T10:40:19Z + +[Term] +id: GO:0071653 +name: negative regulation of chemokine (C-C motif) ligand 1 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1." [GOC:mah] +synonym: "negative regulation of CCL1 production" EXACT [GOC:mah] +synonym: "negative regulation of T cell activation 3 production" EXACT [GOC:mah] +synonym: "negative regulation of TCA-3 production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071652 ! regulation of chemokine (C-C motif) ligand 1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +relationship: negatively_regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071654 +name: positive regulation of chemokine (C-C motif) ligand 1 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1." [GOC:mah] +synonym: "positive regulation of CCL1 production" EXACT [GOC:mah] +synonym: "positive regulation of T cell activation 3 production" EXACT [GOC:mah] +synonym: "positive regulation of TCA-3 production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071652 ! regulation of chemokine (C-C motif) ligand 1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +relationship: positively_regulates GO:0071610 ! chemokine (C-C motif) ligand 1 production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071655 +name: regulation of granulocyte colony-stimulating factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor." [GOC:mah] +synonym: "regulation of colony stimulating factor 3 (granulocyte) production" EXACT [GOC:mah] +synonym: "regulation of CSF3 production" EXACT [GOC:mah] +synonym: "regulation of filgrastim production" EXACT [GOC:mah] +synonym: "regulation of G-CSF production" EXACT [GOC:mah] +synonym: "regulation of granulocyte colony stimulating factor production" EXACT [] +synonym: "regulation of lenograstim production" EXACT [GOC:mah] +synonym: "regulation of pluripoietin production" EXACT [GOC:mah] +is_a: GO:1901256 ! regulation of macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071611 ! granulocyte colony-stimulating factor production +relationship: regulates GO:0071611 ! granulocyte colony-stimulating factor production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071656 +name: negative regulation of granulocyte colony-stimulating factor production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor." [GOC:mah] +synonym: "negative regulation of colony stimulating factor 3 (granulocyte) production" EXACT [GOC:mah] +synonym: "negative regulation of CSF3 production" EXACT [GOC:mah] +synonym: "negative regulation of filgrastim production" EXACT [GOC:mah] +synonym: "negative regulation of G-CSF production" EXACT [GOC:mah] +synonym: "negative regulation of granulocyte colony stimulating factor production" EXACT [] +synonym: "negative regulation of lenograstim production" EXACT [GOC:mah] +synonym: "negative regulation of pluripoietin production" EXACT [GOC:mah] +is_a: GO:0071655 ! regulation of granulocyte colony-stimulating factor production +is_a: GO:1901257 ! negative regulation of macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071611 ! granulocyte colony-stimulating factor production +relationship: negatively_regulates GO:0071611 ! granulocyte colony-stimulating factor production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071657 +name: positive regulation of granulocyte colony-stimulating factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor." [GOC:mah] +synonym: "positive regulation of colony stimulating factor 3 (granulocyte) production" EXACT [GOC:mah] +synonym: "positive regulation of CSF3 production" EXACT [GOC:mah] +synonym: "positive regulation of filgrastim production" EXACT [GOC:mah] +synonym: "positive regulation of G-CSF production" EXACT [GOC:mah] +synonym: "positive regulation of granulocyte colony stimulating factor production" EXACT [] +synonym: "positive regulation of lenograstim production" EXACT [GOC:mah] +synonym: "positive regulation of pluripoietin production" EXACT [GOC:mah] +is_a: GO:0071655 ! regulation of granulocyte colony-stimulating factor production +is_a: GO:1901258 ! positive regulation of macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071611 ! granulocyte colony-stimulating factor production +relationship: positively_regulates GO:0071611 ! granulocyte colony-stimulating factor production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071658 +name: regulation of IP-10 production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of IP-10." [GOC:mah] +synonym: "regulation of chemokine (C-C motif) ligand 10 production" EXACT [GOC:mah] +synonym: "regulation of CXCL10 production" EXACT [GOC:mah] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071612 ! IP-10 production +relationship: regulates GO:0071612 ! IP-10 production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071659 +name: negative regulation of IP-10 production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10." [GOC:mah] +synonym: "negative regulation of chemokine (C-C motif) ligand 10 production" EXACT [GOC:mah] +synonym: "negative regulation of CXCL10 production" EXACT [GOC:mah] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0071658 ! regulation of IP-10 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071612 ! IP-10 production +relationship: negatively_regulates GO:0071612 ! IP-10 production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071660 +name: positive regulation of IP-10 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of IP-10." [GOC:mah] +synonym: "positive regulation of chemokine (C-C motif) ligand 10 production" EXACT [GOC:mah] +synonym: "positive regulation of CXCL10 production" EXACT [GOC:mah] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0071658 ! regulation of IP-10 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071612 ! IP-10 production +relationship: positively_regulates GO:0071612 ! IP-10 production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071661 +name: regulation of granzyme B production +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of production of granzyme B." [GOC:mah] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071613 ! granzyme B production +relationship: regulates GO:0071613 ! granzyme B production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071662 +name: negative regulation of granzyme B production +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B." [GOC:mah] +is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response +is_a: GO:0071661 ! regulation of granzyme B production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071613 ! granzyme B production +relationship: negatively_regulates GO:0071613 ! granzyme B production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071663 +name: positive regulation of granzyme B production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of production of granzyme B." [GOC:mah] +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +is_a: GO:0071661 ! regulation of granzyme B production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071613 ! granzyme B production +relationship: positively_regulates GO:0071613 ! granzyme B production +created_by: mah +creation_date: 2010-02-12T10:41:14Z + +[Term] +id: GO:0071664 +name: catenin-TCF7L2 complex +namespace: cellular_component +def: "A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:rl, GOC:vk, PMID:14661054] +synonym: "catenin-TCF4 complex" EXACT [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: mah +creation_date: 2010-02-12T03:19:16Z + +[Term] +id: GO:0071665 +name: gamma-catenin-TCF7L2 complex +namespace: cellular_component +def: "A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:vk, PMID:14661054] +synonym: "gamma-catenin-TCF4 complex" EXACT [GOC:mah] +synonym: "plakoglobin-TCF4 complex" EXACT [PMID:14661054] +is_a: GO:0071664 ! catenin-TCF7L2 complex +created_by: mah +creation_date: 2010-02-12T03:23:08Z + +[Term] +id: GO:0071666 +name: Slit-Robo signaling complex +namespace: cellular_component +def: "A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate." [GOC:sart, PMID:17062560, PMID:18359766] +synonym: "Slit-Robo signalling complex" EXACT [GOC:mah] +is_a: GO:0032992 ! protein-carbohydrate complex +created_by: mah +creation_date: 2010-02-12T03:35:28Z + +[Term] +id: GO:0071667 +name: DNA/RNA hybrid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RNA/DNA hybrid." [GOC:ecd] +synonym: "RNA/DNA hybrid binding" EXACT [GOC:ecd] +is_a: GO:0003676 ! nucleic acid binding +created_by: mah +creation_date: 2010-02-15T01:51:44Z + +[Term] +id: GO:0071668 +name: plant-type cell wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall." [GOC:mah] +synonym: "plant cell wall assembly" NARROW [] +is_a: GO:0009664 ! plant-type cell wall organization +is_a: GO:0070726 ! cell wall assembly +relationship: part_of GO:0009832 ! plant-type cell wall biogenesis +created_by: mah +creation_date: 2010-02-15T02:19:39Z + +[Term] +id: GO:0071669 +name: plant-type cell wall organization or biogenesis +namespace: biological_process +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall." [GOC:ecd, GOC:mah] +synonym: "plant-type cell wall organisation or biogenesis" EXACT [GOC:mah] +synonym: "plant-type cell wall organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071554 ! cell wall organization or biogenesis +created_by: mah +creation_date: 2010-02-15T02:32:10Z + +[Term] +id: GO:0071670 +name: smooth muscle cell chemotaxis +namespace: biological_process +def: "The directed movement of a smooth muscle cell in response to an external stimulus." [GOC:mah] +is_a: GO:0014909 ! smooth muscle cell migration +is_a: GO:0060326 ! cell chemotaxis +created_by: mah +creation_date: 2010-02-16T01:32:59Z + +[Term] +id: GO:0071671 +name: regulation of smooth muscle cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis." [GOC:mah] +is_a: GO:0014910 ! regulation of smooth muscle cell migration +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071670 ! smooth muscle cell chemotaxis +relationship: regulates GO:0071670 ! smooth muscle cell chemotaxis +created_by: mah +creation_date: 2010-02-16T01:42:03Z + +[Term] +id: GO:0071672 +name: negative regulation of smooth muscle cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis." [GOC:mah] +synonym: "down regulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +synonym: "down-regulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +synonym: "downregulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +synonym: "inhibition of smooth muscle cell chemotaxis" NARROW [GOC:mah] +is_a: GO:0014912 ! negative regulation of smooth muscle cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0071671 ! regulation of smooth muscle cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071670 ! smooth muscle cell chemotaxis +relationship: negatively_regulates GO:0071670 ! smooth muscle cell chemotaxis +created_by: mah +creation_date: 2010-02-16T01:44:28Z + +[Term] +id: GO:0071673 +name: positive regulation of smooth muscle cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis." [GOC:mah] +synonym: "activation of smooth muscle cell chemotaxis" NARROW [GOC:mah] +synonym: "stimulation of smooth muscle cell chemotaxis" NARROW [GOC:mah] +synonym: "up regulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +synonym: "up-regulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +synonym: "upregulation of smooth muscle cell chemotaxis" EXACT [GOC:mah] +is_a: GO:0014911 ! positive regulation of smooth muscle cell migration +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:0071671 ! regulation of smooth muscle cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071670 ! smooth muscle cell chemotaxis +relationship: positively_regulates GO:0071670 ! smooth muscle cell chemotaxis +created_by: mah +creation_date: 2010-02-16T01:48:14Z + +[Term] +id: GO:0071674 +name: mononuclear cell migration +namespace: biological_process +def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] +is_a: GO:0050900 ! leukocyte migration +created_by: mah +creation_date: 2010-02-16T02:11:00Z + +[Term] +id: GO:0071675 +name: regulation of mononuclear cell migration +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071674 ! mononuclear cell migration +relationship: regulates GO:0071674 ! mononuclear cell migration +created_by: mah +creation_date: 2010-02-16T02:11:53Z + +[Term] +id: GO:0071676 +name: negative regulation of mononuclear cell migration +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] +synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah] +synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah] +synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah] +synonym: "inhibition of mononuclear cell migration" NARROW [GOC:mah] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:0071675 ! regulation of mononuclear cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071674 ! mononuclear cell migration +relationship: negatively_regulates GO:0071674 ! mononuclear cell migration +created_by: mah +creation_date: 2010-02-16T02:13:55Z + +[Term] +id: GO:0071677 +name: positive regulation of mononuclear cell migration +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] +synonym: "activation of mononuclear cell migration" NARROW [GOC:mah] +synonym: "stimulation of mononuclear cell migration" NARROW [GOC:mah] +synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah] +synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah] +synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:0071675 ! regulation of mononuclear cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071674 ! mononuclear cell migration +relationship: positively_regulates GO:0071674 ! mononuclear cell migration +created_by: mah +creation_date: 2010-02-16T02:15:29Z + +[Term] +id: GO:0071678 +name: olfactory bulb axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:BHF, GOC:mah] +synonym: "olfactory bulb axon pathfinding" EXACT [GOC:vk] +is_a: GO:0007411 ! axon guidance +created_by: mah +creation_date: 2010-02-17T02:09:34Z + +[Term] +id: GO:0071679 +name: commissural neuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:BHF, GOC:mah] +synonym: "commissural neuron axon pathfinding" EXACT [GOC:vk] +is_a: GO:0007411 ! axon guidance +created_by: mah +creation_date: 2010-02-17T02:21:36Z + +[Term] +id: GO:0071680 +name: response to indole-3-methanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus." [GOC:mah, GOC:yaf] +synonym: "response to indole-3-carbinol" EXACT [CHEBI:24814] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +created_by: mah +creation_date: 2010-02-18T04:05:09Z + +[Term] +id: GO:0071681 +name: cellular response to indole-3-methanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus." [GOC:mah, GOC:yaf] +synonym: "cellular response to indole-3-carbinol" EXACT [CHEBI:24814] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0071680 ! response to indole-3-methanol +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2010-02-18T04:05:29Z + +[Term] +id: GO:0071682 +name: endocytic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of an endocytic vesicle." [GOC:pde] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0030139 ! endocytic vesicle +relationship: part_of GO:0030139 ! endocytic vesicle +created_by: mah +creation_date: 2010-02-18T04:21:53Z + +[Term] +id: GO:0071683 +name: sensory dendrite +namespace: cellular_component +def: "A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron." [GOC:dos, GOC:kmv, GOC:mah] +is_a: GO:0030425 ! dendrite +created_by: mah +creation_date: 2010-02-19T04:17:05Z + +[Term] +id: GO:0071684 +name: organism emergence from protective structure +namespace: biological_process +def: "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." [GOC:mah] +is_a: GO:0032501 ! multicellular organismal process +created_by: mah +creation_date: 2010-02-19T04:23:55Z + +[Term] +id: GO:0071685 +name: NADH dehydrogenase complex (plastoquinone) +namespace: cellular_component +def: "An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids." [DOI:10.1078/0176-1617-00593, GOC:mah] +is_a: GO:0010598 ! NAD(P)H dehydrogenase complex (plastoquinone) +is_a: GO:0030964 ! NADH dehydrogenase complex +relationship: part_of GO:0031976 ! plastid thylakoid +created_by: mah +creation_date: 2010-02-19T05:20:45Z + +[Term] +id: GO:0071686 +name: obsolete horsetail nucleus +namespace: cellular_component +def: "OBSOLETE. The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe." [GOC:vw, PMID:15030757] +comment: This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions. +is_obsolete: true +created_by: mah +creation_date: 2010-02-22T04:52:01Z + +[Term] +id: GO:0071687 +name: obsolete horsetail nucleus leading edge +namespace: cellular_component +def: "OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe." [GOC:mah, GOC:vw, PMID:15030757] +comment: This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions. +is_obsolete: true +created_by: mah +creation_date: 2010-02-22T05:04:40Z + +[Term] +id: GO:0071688 +name: striated muscle myosin thick filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle." [GOC:mah] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0031034 ! myosin filament assembly +relationship: part_of GO:0030239 ! myofibril assembly +created_by: mah +creation_date: 2010-02-25T03:52:21Z + +[Term] +id: GO:0071689 +name: muscle thin filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle." [GOC:mah] +is_a: GO:0007015 ! actin filament organization +relationship: part_of GO:0030239 ! myofibril assembly +created_by: mah +creation_date: 2010-02-25T03:54:06Z + +[Term] +id: GO:0071690 +name: cardiac muscle myosin thick filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle." [GOC:mah] +is_a: GO:0071688 ! striated muscle myosin thick filament assembly +relationship: part_of GO:0055003 ! cardiac myofibril assembly +created_by: mah +creation_date: 2010-02-25T03:55:44Z + +[Term] +id: GO:0071691 +name: cardiac muscle thin filament assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle." [GOC:mah] +is_a: GO:0007015 ! actin filament organization +relationship: part_of GO:0055003 ! cardiac myofibril assembly +created_by: mah +creation_date: 2010-02-25T03:57:01Z + +[Term] +id: GO:0071692 +name: protein localization to extracellular region +namespace: biological_process +def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah] +synonym: "protein localisation in extracellular region" EXACT [GOC:mah] +synonym: "protein localization in extracellular region" EXACT [] +is_a: GO:0008104 ! protein localization +created_by: mah +creation_date: 2010-02-25T04:00:13Z + +[Term] +id: GO:0071693 +name: protein transport within extracellular region +namespace: biological_process +def: "The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0015031 ! protein transport +is_a: GO:0035592 ! establishment of protein localization to extracellular region +created_by: mah +creation_date: 2010-02-25T04:02:35Z + +[Term] +id: GO:0071694 +name: maintenance of protein location in extracellular region +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0045185 ! maintenance of protein location +relationship: part_of GO:0071692 ! protein localization to extracellular region +created_by: mah +creation_date: 2010-02-25T04:04:41Z + +[Term] +id: GO:0071695 +name: anatomical structure maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah] +is_a: GO:0021700 ! developmental maturation +relationship: part_of GO:0048856 ! anatomical structure development +created_by: mah +creation_date: 2010-03-02T11:43:38Z + +[Term] +id: GO:0071696 +name: ectodermal placode development +namespace: biological_process +def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] +is_a: GO:0048856 ! anatomical structure development +created_by: mah +creation_date: 2010-03-02T11:48:01Z + +[Term] +id: GO:0071697 +name: ectodermal placode morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0071696 ! ectodermal placode development +created_by: mah +creation_date: 2010-03-02T11:49:51Z + +[Term] +id: GO:0071698 +name: olfactory placode development +namespace: biological_process +def: "The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] +is_a: GO:0071696 ! ectodermal placode development +created_by: mah +creation_date: 2010-03-02T12:45:14Z + +[Term] +id: GO:0071699 +name: olfactory placode morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] +is_a: GO:0048598 ! embryonic morphogenesis +is_a: GO:0071697 ! ectodermal placode morphogenesis +relationship: part_of GO:0071698 ! olfactory placode development +created_by: mah +creation_date: 2010-03-02T12:45:45Z + +[Term] +id: GO:0071700 +name: olfactory placode maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] +is_a: GO:0071695 ! anatomical structure maturation +relationship: part_of GO:0071698 ! olfactory placode development +created_by: mah +creation_date: 2010-03-02T01:10:54Z + +[Term] +id: GO:0071701 +name: regulation of MAPK export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm." [GOC:dgf] +synonym: "regulation of cytoplasmic translocation of MAP kinase" EXACT [GOC:mah] +synonym: "regulation of cytoplasmic translocation of mitogen-activated protein kinase" EXACT [GOC:mah] +synonym: "regulation of MAPK export from cell nucleus" EXACT [GOC:mah] +synonym: "regulation of MAPK export out of nucleus" EXACT [GOC:mah] +synonym: "regulation of MAPK transport from nucleus to cytoplasm" EXACT [GOC:mah] +synonym: "regulation of MAPK-nucleus export" EXACT [GOC:mah] +is_a: GO:0046825 ! regulation of protein export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045204 ! MAPK export from nucleus +relationship: regulates GO:0045204 ! MAPK export from nucleus +created_by: mah +creation_date: 2010-03-02T01:24:12Z + +[Term] +id: GO:0071702 +name: organic substance transport +namespace: biological_process +def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah] +is_a: GO:0006810 ! transport +created_by: mah +creation_date: 2010-03-08T02:15:14Z + +[Term] +id: GO:0071703 +name: detection of organic substance +namespace: biological_process +def: "The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal." [GOC:mah] +is_a: GO:0009593 ! detection of chemical stimulus +is_a: GO:0010033 ! response to organic substance +created_by: mah +creation_date: 2010-03-08T03:18:44Z + +[Term] +id: GO:0071704 +name: organic substance metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +synonym: "organic molecular entity metabolic process" EXACT [] +synonym: "organic molecular entity metabolism" EXACT [] +synonym: "organic substance metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process +created_by: mah +creation_date: 2010-03-08T03:32:18Z + +[Term] +id: GO:0071705 +name: nitrogen compound transport +namespace: biological_process +def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +is_a: GO:0006810 ! transport +created_by: mah +creation_date: 2010-03-08T03:56:28Z + +[Term] +id: GO:0071706 +name: tumor necrosis factor superfamily cytokine production +namespace: biological_process +def: "The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add] +synonym: "TNF superfamily production" RELATED [GOC:rv] +synonym: "TNFSF cytokine production" EXACT [GOC:add] +is_a: GO:0001816 ! cytokine production +created_by: mah +creation_date: 2010-03-09T02:40:35Z + +[Term] +id: GO:0071707 +name: immunoglobulin heavy chain V-D-J recombination +namespace: biological_process +def: "The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)." [GOC:add, ISBN:0781735149] +synonym: "immunoglobulin V(D)J joining" BROAD [GOC:add] +synonym: "immunoglobulin V(D)J recombination" BROAD [GOC:add] +synonym: "immunoglobulin V-D-J joining" EXACT [GOC:add] +is_a: GO:0033152 ! immunoglobulin V(D)J recombination +created_by: mah +creation_date: 2010-03-09T04:20:31Z + +[Term] +id: GO:0071708 +name: immunoglobulin light chain V-J recombination +namespace: biological_process +def: "The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)." [GOC:add, ISBN:0781735149] +synonym: "immunoglobulin V(D)J joining" BROAD [GOC:add] +synonym: "immunoglobulin V(D)J recombination" BROAD [GOC:add] +synonym: "immunoglobulin V-J joining" EXACT [GOC:add] +is_a: GO:0033152 ! immunoglobulin V(D)J recombination +created_by: mah +creation_date: 2010-03-09T04:22:29Z + +[Term] +id: GO:0071709 +name: membrane assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0044091 ! membrane biogenesis +created_by: mah +creation_date: 2010-03-10T11:19:17Z + +[Term] +id: GO:0071710 +name: membrane macromolecule biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell." [GOC:mah] +synonym: "membrane macromolecule anabolism" EXACT [GOC:mah] +synonym: "membrane macromolecule biosynthesis" EXACT [GOC:mah] +synonym: "membrane macromolecule formation" EXACT [GOC:mah] +synonym: "membrane macromolecule synthesis" EXACT [GOC:mah] +is_a: GO:0070589 ! cellular component macromolecule biosynthetic process +relationship: part_of GO:0044091 ! membrane biogenesis +created_by: mah +creation_date: 2010-03-10T11:29:52Z + +[Term] +id: GO:0071711 +name: basement membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah] +comment: Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer. +synonym: "basement membrane organisation" EXACT [GOC:mah] +is_a: GO:0030198 ! extracellular matrix organization +created_by: mah +creation_date: 2010-03-10T11:57:10Z + +[Term] +id: GO:0071712 +name: ER-associated misfolded protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation." [GOC:mah, GOC:vw, PMID:14607247, PMID:19520858] +comment: See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'. +synonym: "endoplasmic reticulum-associated misfolded protein catabolic process" EXACT [GOC:mah] +synonym: "endoplasmic reticulum-associated misfolded protein catabolism" EXACT [GOC:mah] +synonym: "ER-associated misfolded protein breakdown" EXACT [GOC:mah] +synonym: "ER-associated misfolded protein catabolism" EXACT [GOC:mah] +synonym: "ER-associated misfolded protein degradation" EXACT [GOC:mah] +synonym: "proteasomal protein catabolism of misfolded ER proteins" EXACT [GOC:bf] +is_a: GO:0006515 ! protein quality control for misfolded or incompletely synthesized proteins +is_a: GO:0036503 ! ERAD pathway +relationship: part_of GO:0071218 ! cellular response to misfolded protein +created_by: mah +creation_date: 2010-03-10T12:53:27Z + +[Term] +id: GO:0071713 +name: para-aminobenzoyl-glutamate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate." [GOC:imk, PMID:20190044] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: mah +creation_date: 2010-03-10T01:25:31Z + +[Term] +id: GO:0071714 +name: icosanoid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of icosanoids from one side of a membrane to the other." [GOC:sl] +synonym: "eicosanoid transmembrane transporter activity" EXACT [GOC:sl] +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +relationship: part_of GO:0071715 ! icosanoid transport +created_by: mah +creation_date: 2010-03-10T01:50:08Z + +[Term] +id: GO:0071715 +name: icosanoid transport +namespace: biological_process +def: "The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds." [GOC:mah] +synonym: "eicosanoid transport" EXACT [GOC:sl] +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:1901571 ! fatty acid derivative transport +created_by: mah +creation_date: 2010-03-10T02:47:22Z + +[Term] +id: GO:0071716 +name: leukotriene transport +namespace: biological_process +def: "The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups." [GOC:mah] +is_a: GO:0071715 ! icosanoid transport +property_value: RO:0002161 NCBITaxon:4751 +created_by: mah +creation_date: 2010-03-10T02:53:59Z + +[Term] +id: GO:0071717 +name: thromboxane transport +namespace: biological_process +def: "The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels." [GOC:mah] +is_a: GO:0015908 ! fatty acid transport +is_a: GO:0071715 ! icosanoid transport +created_by: mah +creation_date: 2010-03-10T03:03:49Z + +[Term] +id: GO:0071718 +name: sodium-independent icosanoid transport +namespace: biological_process +def: "The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds." [GOC:mah, GOC:sl] +synonym: "sodium-independent eicosanoid transport" EXACT [GOC:sl] +is_a: GO:0071715 ! icosanoid transport +created_by: mah +creation_date: 2010-03-10T03:05:13Z + +[Term] +id: GO:0071719 +name: sodium-independent leukotriene transport +namespace: biological_process +def: "The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups." [GOC:mah] +is_a: GO:0071716 ! leukotriene transport +is_a: GO:0071718 ! sodium-independent icosanoid transport +created_by: mah +creation_date: 2010-03-10T03:08:42Z + +[Term] +id: GO:0071720 +name: sodium-independent prostaglandin transport +namespace: biological_process +def: "The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] +is_a: GO:0015732 ! prostaglandin transport +is_a: GO:0071718 ! sodium-independent icosanoid transport +created_by: mah +creation_date: 2010-03-10T03:09:10Z + +[Term] +id: GO:0071721 +name: sodium-independent thromboxane transport +namespace: biological_process +def: "The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels." [GOC:mah] +is_a: GO:0071717 ! thromboxane transport +is_a: GO:0071718 ! sodium-independent icosanoid transport +created_by: mah +creation_date: 2010-03-10T03:10:45Z + +[Term] +id: GO:0071722 +name: detoxification of arsenic-containing substance +namespace: biological_process +def: "Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds." [GOC:kmv, PMID:11313333, PMID:20221439] +synonym: "detoxification of arsenic" EXACT [] +is_a: GO:0098754 ! detoxification +relationship: part_of GO:0046685 ! response to arsenic-containing substance +created_by: mah +creation_date: 2010-03-17T01:35:56Z + +[Term] +id: GO:0071723 +name: lipopeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "bacterial lipopeptide binding" NARROW [GOC:add] +synonym: "bacterial lipoprotein binding" RELATED [GOC:add] +is_a: GO:0008289 ! lipid binding +is_a: GO:0042277 ! peptide binding +created_by: mah +creation_date: 2010-03-17T02:13:21Z + +[Term] +id: GO:0071724 +name: response to diacyl bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "response to diacylated bacterial lipoprotein" EXACT [GOC:add] +is_a: GO:0070339 ! response to bacterial lipopeptide +created_by: mah +creation_date: 2010-03-17T02:14:41Z + +[Term] +id: GO:0071725 +name: response to triacyl bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "response to triacylated bacterial lipoprotein" EXACT [GOC:add] +is_a: GO:0070339 ! response to bacterial lipopeptide +created_by: mah +creation_date: 2010-03-17T02:16:40Z + +[Term] +id: GO:0071726 +name: cellular response to diacyl bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "cellular response to diacylated bacterial lipoprotein" EXACT [GOC:add] +is_a: GO:0071221 ! cellular response to bacterial lipopeptide +is_a: GO:0071724 ! response to diacyl bacterial lipopeptide +created_by: mah +creation_date: 2010-03-17T02:17:02Z + +[Term] +id: GO:0071727 +name: cellular response to triacyl bacterial lipopeptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus." [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794] +comment: Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature. +synonym: "cellular response to triacylated bacterial lipoprotein" EXACT [GOC:add] +is_a: GO:0071221 ! cellular response to bacterial lipopeptide +is_a: GO:0071725 ! response to triacyl bacterial lipopeptide +created_by: mah +creation_date: 2010-03-17T02:17:49Z + +[Term] +id: GO:0071728 +name: beak development +namespace: biological_process +def: "The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus." [GOC:lp, ISBN:0702008729] +is_a: GO:0048856 ! anatomical structure development +created_by: mah +creation_date: 2010-03-17T03:52:48Z + +[Term] +id: GO:0071729 +name: beak morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus." [GOC:lp, ISBN:0702008729] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0071728 ! beak development +created_by: mah +creation_date: 2010-03-17T03:54:34Z + +[Term] +id: GO:0071730 +name: beak formation +namespace: biological_process +def: "The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus." [GOC:lp, ISBN:0702008729] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0071729 ! beak morphogenesis +created_by: mah +creation_date: 2010-03-17T03:57:07Z + +[Term] +id: GO:0071731 +name: response to nitric oxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0097366 ! response to bronchodilator +is_a: GO:1901698 ! response to nitrogen compound +created_by: mah +creation_date: 2010-03-17T04:03:38Z + +[Term] +id: GO:0071732 +name: cellular response to nitric oxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] +is_a: GO:0034614 ! cellular response to reactive oxygen species +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0071731 ! response to nitric oxide +is_a: GO:1902170 ! cellular response to reactive nitrogen species +created_by: mah +creation_date: 2010-03-17T04:12:52Z + +[Term] +id: GO:0071733 +name: transcriptional activation by promoter-enhancer looping +namespace: biological_process +def: "The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter." [GOC:mah, PMID:15060134, PMID:19923429] +synonym: "long-range enhancer-promoter communication" RELATED [PMID:15060134] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0090202 ! gene looping +created_by: mah +creation_date: 2010-03-19T02:01:19Z + +[Term] +id: GO:0071734 +name: biotin-[pyruvate-carboxylase] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase)." [GOC:mah, PMID:10551847] +synonym: "biotin-[pyruvate carboxylase] ligase activity" EXACT [GOC:jp] +synonym: "biotin-[pyruvate carboxylase] synthetase activity" EXACT [GOC:mah] +synonym: "biotin-pyruvate carboxylase synthetase activity" EXACT [GOC:mah] +synonym: "biotin-pyruvate-carboxylase ligase activity" EXACT [GOC:mah] +synonym: "biotin:apo-pyruvate-carboxylase ligase" EXACT [GOC:mah] +xref: EC:6.3.4 +is_a: GO:0018271 ! biotin-protein ligase activity +created_by: mah +creation_date: 2010-03-19T02:37:24Z + +[Term] +id: GO:0071735 +name: IgG immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species. +synonym: "IgG1" NARROW [GOC:add] +synonym: "IgG2" NARROW [GOC:add] +synonym: "IgG2a" NARROW [GOC:add] +synonym: "IgG2b" NARROW [GOC:add] +synonym: "IgG2c" NARROW [GOC:add] +synonym: "IgG3" NARROW [GOC:add] +synonym: "IgG4" NARROW [GOC:add] +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071736 +name: IgG immunoglobulin complex, circulating +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species. +synonym: "IgG antibody" NARROW [GOC:add] +synonym: "IgG1 antibody" NARROW [GOC:add] +synonym: "IgG2 antibody" NARROW [GOC:add] +synonym: "IgG2a antibody" NARROW [GOC:add] +synonym: "IgG2b antibody" NARROW [GOC:add] +synonym: "IgG2c antibody" NARROW [GOC:add] +synonym: "IgG3 antibody" NARROW [GOC:add] +synonym: "IgG4 antibody" NARROW [GOC:add] +is_a: GO:0042571 ! immunoglobulin complex, circulating +is_a: GO:0071735 ! IgG immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071737 +name: IgG B cell receptor complex +namespace: cellular_component +def: "An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196] +comment: Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species. +synonym: "membrane-bound IgG" NARROW [GOC:add] +synonym: "membrane-bound IgG1" NARROW [GOC:add] +synonym: "membrane-bound IgG2" NARROW [GOC:add] +synonym: "membrane-bound IgG2a" NARROW [GOC:add] +synonym: "membrane-bound IgG2b" NARROW [GOC:add] +synonym: "membrane-bound IgG2c" NARROW [GOC:add] +synonym: "membrane-bound IgG3" NARROW [GOC:add] +synonym: "membrane-bound IgG4" NARROW [GOC:add] +synonym: "surface IgG" NARROW [GOC:add] +synonym: "surface IgG1" NARROW [GOC:add] +synonym: "surface IgG2" NARROW [GOC:add] +synonym: "surface IgG2a" NARROW [GOC:add] +synonym: "surface IgG2b" NARROW [GOC:add] +synonym: "surface IgG2c" NARROW [GOC:add] +synonym: "surface IgG3" NARROW [GOC:add] +synonym: "surface IgG4" NARROW [GOC:add] +is_a: GO:0019815 ! B cell receptor complex +is_a: GO:0071735 ! IgG immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071738 +name: IgD immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:11282392] +comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071739 +name: IgD immunoglobulin complex, circulating +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:11282392] +comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "IgD antibody" EXACT [GOC:add] +is_a: GO:0042571 ! immunoglobulin complex, circulating +is_a: GO:0071738 ! IgD immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071740 +name: IgD B cell receptor complex +namespace: cellular_component +def: "An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:11282392] +comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "membrane-bound IgD" EXACT [GOC:add] +synonym: "surface IgD" EXACT [GOC:add] +is_a: GO:0019815 ! B cell receptor complex +is_a: GO:0071738 ! IgD immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071741 +name: IgD immunoglobulin complex, GPI-anchored +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells." [GOC:add, ISBN:0781765196, PMID:11282392] +comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "GPI-anchored IgD" EXACT [GOC:add] +is_a: GO:0071738 ! IgD immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071742 +name: IgE immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071743 +name: IgE immunoglobulin complex, circulating +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "IgE antibody" EXACT [GOC:add] +is_a: GO:0042571 ! immunoglobulin complex, circulating +is_a: GO:0071742 ! IgE immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071744 +name: IgE B cell receptor complex +namespace: cellular_component +def: "An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196] +comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "membrane-bound IgE" EXACT [GOC:add] +synonym: "surface IgE" EXACT [GOC:add] +is_a: GO:0019815 ! B cell receptor complex +is_a: GO:0071742 ! IgE immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071745 +name: IgA immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "IgA1 antibody" NARROW [GOC:add] +synonym: "IgA2 antibody" NARROW [GOC:add] +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071746 +name: IgA immunoglobulin complex, circulating +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "IgA antibody" EXACT [GOC:add] +synonym: "IgA1 antibody" NARROW [GOC:add] +synonym: "IgA2 antibody" NARROW [GOC:add] +is_a: GO:0042571 ! immunoglobulin complex, circulating +is_a: GO:0071745 ! IgA immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071747 +name: IgA B cell receptor complex +namespace: cellular_component +def: "An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "membrane-bound IgA" NARROW [GOC:add] +synonym: "membrane-bound IgA1" NARROW [GOC:add] +synonym: "membrane-bound IgA2" NARROW [GOC:add] +synonym: "surface IgA" NARROW [GOC:add] +synonym: "surface IgA1" NARROW [GOC:add] +synonym: "surface IgA2" NARROW [GOC:add] +is_a: GO:0019815 ! B cell receptor complex +is_a: GO:0071745 ! IgA immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071748 +name: monomeric IgA immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "monomeric IgA antibody" EXACT [GOC:add] +synonym: "monomeric IgA1 antibody" NARROW [GOC:add] +synonym: "monomeric IgA2 antibody" NARROW [GOC:add] +is_a: GO:0071746 ! IgA immunoglobulin complex, circulating +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071749 +name: polymeric IgA immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms. +synonym: "pIgA antibody" EXACT [GOC:add] +synonym: "pIgA1 antibody" NARROW [GOC:add] +synonym: "polymeric IgA antibody" EXACT [GOC:add] +synonym: "polymeric IgA1 antibody" NARROW [GOC:add] +is_a: GO:0071746 ! IgA immunoglobulin complex, circulating +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071750 +name: dimeric IgA immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form. +synonym: "dimeric IgA antibody" EXACT [GOC:add] +synonym: "dimeric IgA1 antibody" NARROW [GOC:add] +is_a: GO:0071749 ! polymeric IgA immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071751 +name: secretory IgA immunoglobulin complex +namespace: cellular_component +def: "A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA. +synonym: "secretory IgA antibody" EXACT [GOC:add] +synonym: "sIgA antibody" EXACT [GOC:add] +synonym: "sIgA1 antibody" NARROW [GOC:add] +is_a: GO:0071749 ! polymeric IgA immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071752 +name: secretory dimeric IgA immunoglobulin complex +namespace: cellular_component +def: "A dimeric form of secretory IgA immunoglobulin complex." [GOC:add, ISBN:0781765196, PMID:16362985] +comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form. +synonym: "secretory dimeric IgA antibody" EXACT [GOC:add] +synonym: "secretory dimeric IgA1 antibody" NARROW [GOC:add] +is_a: GO:0071750 ! dimeric IgA immunoglobulin complex +is_a: GO:0071751 ! secretory IgA immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071753 +name: IgM immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:20176268] +comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071754 +name: IgM immunoglobulin complex, circulating +namespace: cellular_component +def: "A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:20176268] +comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "IgM antibody" EXACT [GOC:add] +is_a: GO:0042571 ! immunoglobulin complex, circulating +is_a: GO:0071753 ! IgM immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071755 +name: IgM B cell receptor complex +namespace: cellular_component +def: "An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:20176268] +comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "membrane-bound IgM" NARROW [GOC:add] +synonym: "surface IgM" NARROW [GOC:add] +is_a: GO:0019815 ! B cell receptor complex +is_a: GO:0071753 ! IgM immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071756 +name: pentameric IgM immunoglobulin complex +namespace: cellular_component +def: "A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide." [GOC:add, ISBN:0781765196, PMID:20176268] +comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "pentameric IgM antibody" EXACT [GOC:add] +is_a: GO:0071754 ! IgM immunoglobulin complex, circulating +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071757 +name: hexameric IgM immunoglobulin complex +namespace: cellular_component +def: "A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide." [GOC:add, ISBN:0781765196, PMID:20176268] +comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available. +synonym: "hexameric IgM antibody" EXACT [GOC:add] +is_a: GO:0071754 ! IgM immunoglobulin complex, circulating +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071758 +name: IgW immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgW immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgW is found in fish. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071759 +name: IgX immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgX immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgX is found in amphibians. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071760 +name: IgY immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196] +comment: Note that an IgY immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgY is found in amphibians, reptiles, and birds. +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071761 +name: IgZ immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish." [GOC:add, ISBN:0781765196] +comment: Note that an IgZ immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgZ is found in bony fish, and called IgT in certain species, such as trout. +synonym: "IgT antibody" NARROW [GOC:add] +synonym: "IgT immunoglobulin complex" EXACT [ISBN:0781765196] +synonym: "IgZ antibody" NARROW [GOC:add] +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071762 +name: heavy chain immunoglobulin complex +namespace: cellular_component +def: "A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains." [GOC:add, ISBN:0781765196, PMID:12543123, PMID:16051357] +comment: Note that a heavy chain immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgNAR is found in serum of cartilaginous fish as a heavy chain dimer without immunoglobulin light chains. Note that HCab is found in camels as a heavy chain dimer without immunoglobulin light chains. +synonym: "HCab" NARROW [GOC:add] +synonym: "Ig NAR immunoglobulin complex" NARROW [GOC:add] +synonym: "IgNAR antibody" NARROW [GOC:add] +synonym: "IgNAR immunoglobulin complex" NARROW [GOC:add] +is_a: GO:0019814 ! immunoglobulin complex +created_by: mah +creation_date: 2010-03-24T01:44:53Z + +[Term] +id: GO:0071763 +name: nuclear membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah] +synonym: "nuclear membrane organisation" EXACT [GOC:mah] +synonym: "nuclear membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0006998 ! nuclear envelope organization +created_by: mah +creation_date: 2010-03-29T03:59:35Z + +[Term] +id: GO:0071764 +name: nuclear outer membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah] +synonym: "nuclear outer membrane organisation" EXACT [GOC:mah] +synonym: "nuclear outer membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071763 ! nuclear membrane organization +created_by: mah +creation_date: 2010-03-29T04:03:37Z + +[Term] +id: GO:0071765 +name: nuclear inner membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane." [GOC:mah] +synonym: "nuclear inner membrane organisation" EXACT [GOC:mah] +synonym: "nuclear inner membrane organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071763 ! nuclear membrane organization +created_by: mah +creation_date: 2010-03-29T04:04:57Z + +[Term] +id: GO:0071766 +name: Actinobacterium-type cell wall biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface." [GOC:mah, PMID:15653820, PMID:3149973] +is_a: GO:0009273 ! peptidoglycan-based cell wall biogenesis +created_by: mah +creation_date: 2010-03-29T04:12:51Z + +[Term] +id: GO:0071767 +name: mycolic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain." [GOC:mah, PMID:15653820] +synonym: "mycolate metabolic process" EXACT [GOC:mah] +synonym: "mycolic acid metabolism" EXACT [GOC:mah] +is_a: GO:0006631 ! fatty acid metabolic process +created_by: mah +creation_date: 2010-03-29T04:33:31Z + +[Term] +id: GO:0071768 +name: mycolic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain." [GOC:mah, MetaCyc:PWYG-321, PMID:15653820] +synonym: "mycolate biosynthetic process" EXACT [GOC:mah] +synonym: "mycolic acid anabolism" EXACT [GOC:mah] +synonym: "mycolic acid biosynthesis" EXACT [GOC:mah] +synonym: "mycolic acid formation" EXACT [GOC:mah] +synonym: "mycolic acid synthesis" EXACT [GOC:mah] +xref: MetaCyc:PWYG-321 +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0044038 ! cell wall macromolecule biosynthetic process +is_a: GO:0071767 ! mycolic acid metabolic process +relationship: part_of GO:0071766 ! Actinobacterium-type cell wall biogenesis +created_by: mah +creation_date: 2010-03-29T04:36:10Z + +[Term] +id: GO:0071769 +name: mycolate cell wall layer assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer." [GOC:mah, MetaCyc:PWY-6397, PMID:15653820, PMID:3149973] +synonym: "mycolate cell wall layer biogenesis" RELATED [GOC:mah] +xref: MetaCyc:PWY-6397 +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0071766 ! Actinobacterium-type cell wall biogenesis +created_by: mah +creation_date: 2010-03-29T04:40:45Z + +[Term] +id: GO:0071770 +name: DIM/DIP cell wall layer assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall." [GOC:mah, GOC:pr, PMID:15653820, PMID:3149973] +synonym: "DIM cell wall layer assembly" EXACT [GOC:mah] +synonym: "DIM/DIP cell wall layer biogenesis" RELATED [GOC:mah] +synonym: "PDIM cell wall layer assembly" EXACT [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0071766 ! Actinobacterium-type cell wall biogenesis +created_by: mah +creation_date: 2010-03-29T04:47:19Z + +[Term] +id: GO:0071771 +name: aldehyde decarbonylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO." [GOC:kad, PMID:6593720, PMID:8718622] +synonym: "decarbonylase activity" EXACT [GOC:kad, GOC:mah] +is_a: GO:0016830 ! carbon-carbon lyase activity +created_by: mah +creation_date: 2010-04-01T12:02:50Z + +[Term] +id: GO:0071772 +name: response to BMP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus." [GOC:mah, GOC:yaf] +synonym: "response to BMP stimulus" EXACT [GOC:dos] +synonym: "response to bone morphogenetic protein stimulus" EXACT [GOC:mah] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: mah +creation_date: 2010-08-31T11:02:11Z + +[Term] +id: GO:0071773 +name: cellular response to BMP stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus." [GOC:mah, GOC:yaf] +synonym: "cellular response to bone morphogenetic protein stimulus" EXACT [GOC:mah] +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:0071772 ! response to BMP +created_by: mah +creation_date: 2010-08-31T11:04:45Z + +[Term] +id: GO:0071774 +name: response to fibroblast growth factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus." [GOC:mah] +synonym: "response to FGF stimulus" EXACT [GOC:mah] +synonym: "response to fibroblast growth factor stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: mah +creation_date: 2010-08-31T11:06:32Z + +[Term] +id: GO:0071778 +name: obsolete WINAC complex +namespace: cellular_component +def: "OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors." [GOC:BHF, PMID:12837248] +comment: This term was made obsolete because the paper describing the characterization of this complex, which was used to create this term, has been retracted. +synonym: "WINAC complex" EXACT [] +is_obsolete: true +created_by: mah +creation_date: 2010-08-31T12:19:54Z + +[Term] +id: GO:0071781 +name: endoplasmic reticulum cisternal network +namespace: cellular_component +def: "A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells." [GOC:vw, PMID:16469703, PMID:20434336] +synonym: "ER cisternal network" EXACT [GOC:mah] +is_a: GO:0098827 ! endoplasmic reticulum subcompartment +created_by: mah +creation_date: 2010-09-01T01:29:54Z + +[Term] +id: GO:0071782 +name: endoplasmic reticulum tubular network +namespace: cellular_component +def: "A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section." [GOC:vw, PMID:16469703, PMID:20434336] +synonym: "ER tubular network" EXACT [GOC:mah] +is_a: GO:0098827 ! endoplasmic reticulum subcompartment +created_by: mah +creation_date: 2010-09-01T01:32:55Z + +[Term] +id: GO:0071783 +name: endoplasmic reticulum cisternal network organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section." [GOC:vw, PMID:16469703, PMID:20434336] +synonym: "endoplasmic reticulum cisternal network organisation" EXACT [GOC:mah] +synonym: "ER cisternal network organisation" EXACT [GOC:mah] +synonym: "ER cisternal network organization" EXACT [GOC:mah] +is_a: GO:0007029 ! endoplasmic reticulum organization +created_by: mah +creation_date: 2010-09-01T01:47:28Z + +[Term] +id: GO:0071784 +name: endoplasmic reticulum cisternal network assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section." [GOC:mah, PMID:16469703, PMID:20434336] +synonym: "endoplasmic reticulum cisternal network formation" EXACT [GOC:mah] +synonym: "ER cisternal network assembly" EXACT [GOC:mah] +synonym: "ER cisternal network formation" EXACT [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0071783 ! endoplasmic reticulum cisternal network organization +created_by: mah +creation_date: 2010-09-01T01:50:49Z + +[Term] +id: GO:0071785 +name: endoplasmic reticulum cisternal network maintenance +namespace: biological_process +def: "The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section." [GOC:mah, PMID:16469703, PMID:20434336] +synonym: "ER cisternal network maintenance" EXACT [GOC:mah] +is_a: GO:0043954 ! cellular component maintenance +is_a: GO:0071783 ! endoplasmic reticulum cisternal network organization +created_by: mah +creation_date: 2010-09-01T01:52:26Z + +[Term] +id: GO:0071786 +name: endoplasmic reticulum tubular network organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section." [GOC:vw, PMID:16469703, PMID:20434336] +synonym: "endoplasmic reticulum tubular network organisation" EXACT [GOC:mah] +synonym: "ER tubular network organisation" EXACT [GOC:mah] +synonym: "ER tubular network organization" EXACT [GOC:mah] +is_a: GO:0007029 ! endoplasmic reticulum organization +created_by: mah +creation_date: 2010-09-01T01:53:51Z + +[Term] +id: GO:0071787 +name: endoplasmic reticulum tubular network formation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section." [GOC:mah, GOC:vw, PMID:16469703, PMID:20434336] +synonym: "endoplasmic reticulum tubular network assembly" EXACT [] +synonym: "ER tubular network assembly" EXACT [GOC:mah] +synonym: "ER tubular network formation" EXACT [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: mah +creation_date: 2010-09-01T01:54:29Z + +[Term] +id: GO:0071788 +name: endoplasmic reticulum tubular network maintenance +namespace: biological_process +def: "The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section." [GOC:mah, PMID:16469703, PMID:20434336] +synonym: "ER tubular network maintenance" EXACT [GOC:mah] +is_a: GO:0043954 ! cellular component maintenance +is_a: GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: mah +creation_date: 2010-09-01T01:55:06Z + +[Term] +id: GO:0071791 +name: chemokine (C-C motif) ligand 5 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 5." [GOC:add, GOC:amm] +synonym: "CCL5 binding" EXACT [GOC:add, GOC:amm] +synonym: "RANTES binding" EXACT [GOC:bf] +synonym: "Regulated upon Activation, Normal T-cell Expressed, and Secreted binding" EXACT [GOC:add] +is_a: GO:0019957 ! C-C chemokine binding +created_by: mah +creation_date: 2010-09-01T02:28:22Z + +[Term] +id: GO:0071792 +name: bacillithiol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species." [GOC:dh, PMID:20308541] +synonym: "bacillithiol metabolism" EXACT [GOC:mah] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0051186 ! cofactor metabolic process +created_by: mah +creation_date: 2010-09-02T11:13:47Z + +[Term] +id: GO:0071793 +name: bacillithiol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species." [GOC:dh, PMID:20308541] +synonym: "bacillithiol anabolism" EXACT [GOC:mah] +synonym: "bacillithiol biosynthesis" EXACT [GOC:mah] +synonym: "bacillithiol formation" EXACT [GOC:mah] +synonym: "bacillithiol synthesis" EXACT [GOC:mah] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:0071792 ! bacillithiol metabolic process +created_by: mah +creation_date: 2010-09-02T11:16:04Z + +[Term] +id: GO:0071794 +name: CAP-Gly domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets." [GOC:mah, InterPro:IPR000938] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-09-02T02:02:53Z + +[Term] +id: GO:0071795 +name: K11-linked polyubiquitin modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein." [GOC:sp, PMID:18775313] +is_a: GO:0031593 ! polyubiquitin modification-dependent protein binding +created_by: mah +creation_date: 2010-09-02T02:11:41Z + +[Term] +id: GO:0071796 +name: K6-linked polyubiquitin modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein." [GOC:sp, PMID:17525341, PMID:20351172] +is_a: GO:0031593 ! polyubiquitin modification-dependent protein binding +created_by: mah +creation_date: 2010-09-02T02:13:07Z + +[Term] +id: GO:0071797 +name: LUBAC complex +namespace: cellular_component +def: "A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex." [GOC:sp, PMID:17006537, PMID:19136968, PMID:21455180] +is_a: GO:0000151 ! ubiquitin ligase complex +created_by: mah +creation_date: 2010-09-02T04:09:55Z + +[Term] +id: GO:0071798 +name: response to prostaglandin D +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus." [GOC:sl] +synonym: "response to prostaglandin D stimulus" EXACT [GOC:dos] +is_a: GO:0034694 ! response to prostaglandin +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: mah +creation_date: 2010-09-03T10:48:03Z + +[Term] +id: GO:0071799 +name: cellular response to prostaglandin D stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus." [GOC:sl] +is_a: GO:0071379 ! cellular response to prostaglandin stimulus +is_a: GO:0071798 ! response to prostaglandin D +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2010-09-03T10:48:35Z + +[Term] +id: GO:0071800 +name: podosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell." [GOC:mah, GOC:sl] +is_a: GO:0065003 ! protein-containing complex assembly +is_a: GO:0070925 ! organelle assembly +created_by: mah +creation_date: 2010-09-03T11:00:45Z + +[Term] +id: GO:0071801 +name: regulation of podosome assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of podosome assembly." [GOC:mah, GOC:sl] +comment: Note that the assembly is regulated by several small GTPases of the Rab and Rho families. +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071800 ! podosome assembly +relationship: regulates GO:0071800 ! podosome assembly +created_by: mah +creation_date: 2010-09-03T01:34:29Z + +[Term] +id: GO:0071802 +name: negative regulation of podosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate or extent of podosome assembly." [GOC:mah, GOC:sl] +synonym: "down regulation of podosome assembly" EXACT [GOC:mah] +synonym: "down-regulation of podosome assembly" EXACT [GOC:mah] +synonym: "downregulation of podosome assembly" EXACT [GOC:mah] +synonym: "inhibition of podosome assembly" NARROW [GOC:mah] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0071801 ! regulation of podosome assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071800 ! podosome assembly +relationship: negatively_regulates GO:0071800 ! podosome assembly +created_by: mah +creation_date: 2010-09-03T01:49:14Z + +[Term] +id: GO:0071803 +name: positive regulation of podosome assembly +namespace: biological_process +def: "Any process that activates or increases the rate or extent of podosome assembly." [GOC:mah, GOC:sl] +synonym: "activation of podosome assembly" NARROW [GOC:mah] +synonym: "stimulation of podosome assembly" NARROW [GOC:mah] +synonym: "up regulation of podosome assembly" EXACT [GOC:mah] +synonym: "up-regulation of podosome assembly" EXACT [GOC:mah] +synonym: "upregulation of podosome assembly" EXACT [GOC:mah] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0071801 ! regulation of podosome assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071800 ! podosome assembly +relationship: positively_regulates GO:0071800 ! podosome assembly +created_by: mah +creation_date: 2010-09-03T01:50:50Z + +[Term] +id: GO:0071805 +name: potassium ion transmembrane transport +namespace: biological_process +alt_id: GO:0010163 +def: "A process in which a potassium ion is transported from one side of a membrane to the other." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "high affinity potassium ion import" NARROW [] +synonym: "high affinity potassium ion uptake" NARROW [GOC:dph, GOC:tb] +synonym: "high-affinity potassium ion import" NARROW [] +synonym: "high-affinity potassium ion uptake" NARROW [GOC:dph, GOC:tb] +synonym: "potassium ion membrane transport" EXACT [] +is_a: GO:0006813 ! potassium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2010-09-03T02:43:49Z + +[Term] +id: GO:0071806 +name: protein transmembrane transport +namespace: biological_process +def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +subset: goslim_drosophila +synonym: "protein membrane transport" EXACT [] +is_a: GO:0015031 ! protein transport +is_a: GO:0055085 ! transmembrane transport +created_by: mah +creation_date: 2010-09-03T02:54:26Z + +[Term] +id: GO:0071807 +name: replication fork arrest involved in DNA replication termination +namespace: biological_process +def: "A replication fork arrest process that contributes to the termination of DNA replication." [GOC:mah, PMID:17347517, PMID:20797631] +is_a: GO:0043111 ! replication fork arrest +intersection_of: GO:0043111 ! replication fork arrest +intersection_of: part_of GO:0006274 ! DNA replication termination +relationship: part_of GO:0006274 ! DNA replication termination +created_by: mah +creation_date: 2010-09-03T03:26:38Z + +[Term] +id: GO:0071808 +name: satellite fibril +namespace: cellular_component +def: "An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section)." [GOC:mah, GOC:sl, PMID:20108326] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005930 ! axoneme +created_by: mah +creation_date: 2010-09-03T03:42:14Z + +[Term] +id: GO:0071809 +name: regulation of fever generation by regulation of prostaglandin biosynthesis +namespace: biological_process +def: "Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:BHF, GOC:dph, GOC:mah] +is_a: GO:0031392 ! regulation of prostaglandin biosynthetic process +is_a: GO:0031620 ! regulation of fever generation +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0100008 ! regulation of fever generation by prostaglandin biosynthetic process +relationship: regulates GO:0100008 ! regulation of fever generation by prostaglandin biosynthetic process +created_by: mah +creation_date: 2010-09-03T05:07:17Z + +[Term] +id: GO:0071810 +name: regulation of fever generation by regulation of prostaglandin secretion +namespace: biological_process +def: "Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:BHF, GOC:dph, GOC:mah] +is_a: GO:0031620 ! regulation of fever generation +is_a: GO:0032306 ! regulation of prostaglandin secretion +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0100009 ! regulation of fever generation by prostaglandin secretion +relationship: regulates GO:0100009 ! regulation of fever generation by prostaglandin secretion +created_by: mah +creation_date: 2010-09-03T05:09:27Z + +[Term] +id: GO:0071811 +name: positive regulation of fever generation by positive regulation of prostaglandin biosynthesis +namespace: biological_process +def: "Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:BHF, GOC:dph, GOC:mah] +is_a: GO:0031394 ! positive regulation of prostaglandin biosynthetic process +is_a: GO:0031622 ! positive regulation of fever generation +intersection_of: GO:0031394 ! positive regulation of prostaglandin biosynthetic process +intersection_of: positively_regulates GO:0001660 ! fever generation +created_by: mah +creation_date: 2010-09-03T05:10:05Z + +[Term] +id: GO:0071812 +name: positive regulation of fever generation by positive regulation of prostaglandin secretion +namespace: biological_process +def: "Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell." [GOC:BHF, GOC:dph, GOC:mah] +is_a: GO:0031622 ! positive regulation of fever generation +is_a: GO:0032308 ! positive regulation of prostaglandin secretion +intersection_of: GO:0031622 ! positive regulation of fever generation +intersection_of: positively_regulates GO:0032310 ! prostaglandin secretion +created_by: mah +creation_date: 2010-09-03T05:10:36Z + +[Term] +id: GO:0071813 +name: lipoprotein particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids." [GOC:BHF, GOC:mah] +synonym: "lipoprotein binding" RELATED [GOC:mah] +synonym: "plasma lipoprotein binding" RELATED [GOC:mah] +synonym: "plasma lipoprotein particle binding" EXACT [GOC:mah] +is_a: GO:0071814 ! protein-lipid complex binding +created_by: mah +creation_date: 2010-09-06T03:16:01Z + +[Term] +id: GO:0071814 +name: protein-lipid complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules." [GOC:BHF, GOC:mah] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2010-09-06T04:26:27Z + +[Term] +id: GO:0071815 +name: intermediate-density lipoprotein particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm." [GOC:BHF, GOC:mah] +synonym: "IDL binding" EXACT [GOC:BHF] +synonym: "intermediate-density lipoprotein binding" EXACT [GOC:dph] +is_a: GO:0071813 ! lipoprotein particle binding +created_by: mah +creation_date: 2010-09-06T04:28:35Z + +[Term] +id: GO:0071816 +name: tail-anchored membrane protein insertion into ER membrane +namespace: biological_process +def: "A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region." [GOC:mah, GOC:sp, PMID:20516149, PMID:20676083] +synonym: "protein insertion of tail-anchored membrane proteins into ER membrane" EXACT [GOC:sp] +synonym: "tail-anchored membrane protein insertion into endoplasmic reticulum membrane" EXACT [GOC:mah] +synonym: "type II transmembrane protein insertion into ER membrane" EXACT [GOC:mah, GOC:sp] +is_a: GO:0045048 ! protein insertion into ER membrane +created_by: mah +creation_date: 2010-09-06T04:55:16Z + +[Term] +id: GO:0071817 +name: MMXD complex +namespace: cellular_component +def: "A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation." [GOC:sp, PMID:20797633] +synonym: "MMS19-MIP18-XPD complex" EXACT [GOC:sp, PMID:20797633] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005819 ! spindle +created_by: mah +creation_date: 2010-09-07T10:53:42Z + +[Term] +id: GO:0071818 +name: BAT3 complex +namespace: cellular_component +def: "A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD)." [GOC:bf, GOC:mah, GOC:sp, PMID:20676083, PMID:21636303] +synonym: "Bag6 complex" EXACT [PMID:21636303] +synonym: "BAG6-UBL4A-TRC35 complex" EXACT [PMID:21636303] +synonym: "BAT3-TRC35-UBL4A complex" RELATED [PMID:20676083] +is_a: GO:0072379 ! ER membrane insertion complex +created_by: mah +creation_date: 2010-09-07T11:01:38Z + +[Term] +id: GO:0071819 +name: DUBm complex +namespace: cellular_component +def: "A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p." [PMID:19226466, PMID:20395473] +synonym: "deubiquitinating module" EXACT [GOC:jp, PMID:20395473] +synonym: "deubiquitination module" EXACT [PMID:19226466] +synonym: "SAGA DUBm complex" NARROW [GOC:jp] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2010-09-07T11:19:28Z + +[Term] +id: GO:0071820 +name: N-box binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses." [GOC:yaf, PMID:11498047] +comment: Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16. +synonym: "N box binding" EXACT [GOC:mah] +synonym: "N-box promoter binding" EXACT [GOC:mah] +is_a: GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding +created_by: mah +creation_date: 2010-09-07T11:55:32Z + +[Term] +id: GO:0071821 +name: FANCM-MHF complex +namespace: cellular_component +def: "A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes." [GOC:mah, GOC:vw, PMID:20347428] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: mah +creation_date: 2010-09-07T12:08:38Z + +[Term] +id: GO:0071823 +name: protein-carbohydrate complex subunit organization +namespace: biological_process +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex." [GOC:mah] +synonym: "protein-carbohydrate complex subunit organisation" EXACT [GOC:mah] +is_a: GO:0043933 ! protein-containing complex subunit organization +created_by: mah +creation_date: 2010-09-08T10:03:03Z + +[Term] +id: GO:0071824 +name: protein-DNA complex subunit organization +namespace: biological_process +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." [GOC:mah] +synonym: "DNA-protein complex subunit organization" EXACT [GOC:mah] +synonym: "protein-DNA complex subunit organisation" EXACT [GOC:mah] +is_a: GO:0043933 ! protein-containing complex subunit organization +created_by: mah +creation_date: 2010-09-08T10:03:26Z + +[Term] +id: GO:0071825 +name: protein-lipid complex subunit organization +namespace: biological_process +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex." [GOC:mah] +synonym: "protein-lipid complex subunit organisation" EXACT [GOC:mah] +is_a: GO:0043933 ! protein-containing complex subunit organization +created_by: mah +creation_date: 2010-09-08T10:04:36Z + +[Term] +id: GO:0071826 +name: ribonucleoprotein complex subunit organization +namespace: biological_process +def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah] +synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah] +synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah] +synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah] +is_a: GO:0043933 ! protein-containing complex subunit organization +created_by: mah +creation_date: 2010-09-08T10:10:35Z + +[Term] +id: GO:0071827 +name: plasma lipoprotein particle organization +namespace: biological_process +def: "A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins." [GOC:BHF, GOC:mah] +synonym: "plasma lipoprotein particle organisation" EXACT [GOC:mah] +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0071825 ! protein-lipid complex subunit organization +created_by: mah +creation_date: 2010-09-08T10:32:26Z + +[Term] +id: GO:0071828 +name: apolipoprotein E recycling +namespace: biological_process +def: "The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle." [GOC:BHF, PMID:16373604] +synonym: "APOE recycling" EXACT [GOC:BHF] +is_a: GO:0015031 ! protein transport +relationship: part_of GO:0034380 ! high-density lipoprotein particle assembly +relationship: part_of GO:0034382 ! chylomicron remnant clearance +created_by: mah +creation_date: 2010-09-08T11:05:15Z + +[Term] +id: GO:0071829 +name: plasma lipoprotein particle disassembly +namespace: biological_process +def: "The disaggregation of a plasma lipoprotein particle into its constituent components." [GOC:mah] +is_a: GO:0032987 ! protein-lipid complex disassembly +is_a: GO:0071827 ! plasma lipoprotein particle organization +relationship: part_of GO:0097006 ! regulation of plasma lipoprotein particle levels +created_by: mah +creation_date: 2010-09-08T11:14:21Z + +[Term] +id: GO:0071830 +name: triglyceride-rich lipoprotein particle clearance +namespace: biological_process +def: "The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF] +is_a: GO:0034381 ! plasma lipoprotein particle clearance +created_by: mah +creation_date: 2010-09-08T11:23:55Z + +[Term] +id: GO:0071831 +name: intermediate-density lipoprotein particle clearance +namespace: biological_process +def: "The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:BHF] +synonym: "IDL clearance" EXACT [GOC:BHF] +is_a: GO:0071830 ! triglyceride-rich lipoprotein particle clearance +created_by: mah +creation_date: 2010-09-08T11:26:12Z + +[Term] +id: GO:0071832 +name: peptide pheromone export involved in regulation of conjugation +namespace: biological_process +def: "The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms." [GOC:elh, GOC:jh, GOC:mah] +is_a: GO:0000770 ! peptide pheromone export +is_a: GO:0046999 ! regulation of conjugation +intersection_of: GO:0000770 ! peptide pheromone export +intersection_of: regulates GO:0000746 ! conjugation +created_by: mah +creation_date: 2010-09-09T11:06:46Z + +[Term] +id: GO:0071833 +name: peptide pheromone export involved in positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types." [GOC:elh, GOC:jh, GOC:mah] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +is_a: GO:0071832 ! peptide pheromone export involved in regulation of conjugation +intersection_of: GO:0000770 ! peptide pheromone export +intersection_of: positively_regulates GO:0000747 ! conjugation with cellular fusion +created_by: mah +creation_date: 2010-09-09T11:09:43Z + +[Term] +id: GO:0071834 +name: mating pheromone secretion +namespace: biological_process +def: "The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction." [GOC:mah] +synonym: "mating-type pheromone secretion" EXACT [GOC:vw] +is_a: GO:0030072 ! peptide hormone secretion +created_by: mah +creation_date: 2010-09-09T11:22:35Z + +[Term] +id: GO:0071835 +name: mating pheromone secretion involved in regulation of conjugation +namespace: biological_process +def: "The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms." [GOC:elh, GOC:jh, GOC:mah] +synonym: "mating-type pheromone secretion involved in conjugation" EXACT [GOC:mah, GOC:vw] +is_a: GO:0071834 ! mating pheromone secretion +intersection_of: GO:0071834 ! mating pheromone secretion +intersection_of: part_of GO:0000746 ! conjugation +relationship: part_of GO:0000746 ! conjugation +created_by: mah +creation_date: 2010-09-09T11:23:19Z + +[Term] +id: GO:0071836 +name: nectar secretion +namespace: biological_process +def: "The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins." [GOC:kad, PMID:19861655] +synonym: "nectar production" RELATED [GOC:kad] +is_a: GO:0046903 ! secretion +created_by: mah +creation_date: 2010-09-09T01:06:04Z + +[Term] +id: GO:0071837 +name: HMG box domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin." [GOC:yaf, InterPro:IPR009071, PMID:18445004] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-09-10T12:05:45Z + +[Term] +id: GO:0071838 +name: cell proliferation in bone marrow +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow." [GOC:mah, GOC:yaf, PMID:17063141] +synonym: "bone marrow cell proliferation" EXACT [GOC:yaf] +is_a: GO:0008283 ! cell population proliferation +created_by: mah +creation_date: 2010-09-10T12:15:41Z + +[Term] +id: GO:0071839 +name: apoptotic process in bone marrow cell +namespace: biological_process +def: "The apoptotic process in cells in the bone marrow." [GOC:mah, GOC:mtg_apoptosis, PMID:17063141] +synonym: "apoptosis in bone marrow" NARROW [] +synonym: "apoptotic process in bone marrow cell" EXACT [] +synonym: "bone marrow cell apoptosis" EXACT [GOC:yaf] +synonym: "bone marrow cell programmed cell death by apoptosis" EXACT [GOC:mah] +synonym: "killing of bone marrow cells" EXACT [GOC:mah] +synonym: "programmed cell death of bone marrow cells by apoptosis" EXACT [GOC:mah] +synonym: "programmed cell death, bone marrow cells" EXACT [GOC:mah] +is_a: GO:0006915 ! apoptotic process +created_by: mah +creation_date: 2010-09-10T12:19:18Z + +[Term] +id: GO:0071840 +name: cellular component organization or biogenesis +namespace: biological_process +alt_id: GO:0071841 +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah] +subset: goslim_flybase_ribbon +subset: goslim_metagenomics +synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah] +synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah] +synonym: "cellular component organization or biogenesis at cellular level" EXACT [] +is_a: GO:0009987 ! cellular process +created_by: mah +creation_date: 2010-09-10T01:39:16Z + +[Term] +id: GO:0071846 +name: actin filament debranching +namespace: biological_process +def: "An actin filament severing process that results in the removal of actin filament branches specifically at the branch points." [GOC:jh, GOC:mah, PMID:20362448] +is_a: GO:0051014 ! actin filament severing +created_by: mah +creation_date: 2010-09-10T02:15:42Z + +[Term] +id: GO:0071847 +name: TNFSF11-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:signaling, PMID:18606301, PR:000002107] +synonym: "RANKL-mediated signaling pathway" EXACT [GOC:BHF] +synonym: "receptor activator of nuclear factor kappa-B ligand signaling pathway" EXACT [Wikipedia:RANKL] +synonym: "TNF-related activation-induced cytokine-mediated signaling pathway" EXACT [Wikipedia:RANKL] +synonym: "TNFSF11-mediated signalling pathway" EXACT [GOC:mah] +synonym: "tumor necrosis factor superfamily member 11-mediated signaling pathway" EXACT [Wikipedia:RANKL] +is_a: GO:0033209 ! tumor necrosis factor-mediated signaling pathway +created_by: mah +creation_date: 2010-09-10T02:22:42Z + +[Term] +id: GO:0071848 +name: positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling +namespace: biological_process +def: "Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade." [GOC:BHF, PMID:18606301] +synonym: "positive regulation of ERK1 and ERK2 cascade via RANKL-mediated signaling" EXACT [GOC:BHF] +synonym: "positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalling" EXACT [GOC:mah] +is_a: GO:0070374 ! positive regulation of ERK1 and ERK2 cascade +is_a: GO:0071847 ! TNFSF11-mediated signaling pathway +created_by: mah +creation_date: 2010-09-10T02:25:31Z + +[Term] +id: GO:0071849 +name: G1 cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen." [GOC:vw] +is_a: GO:0007050 ! cell cycle arrest +created_by: mah +creation_date: 2010-09-10T02:46:11Z + +[Term] +id: GO:0071850 +name: mitotic cell cycle arrest +namespace: biological_process +def: "The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M)." [GOC:mah] +synonym: "arrest of mitotic cell cycle progression" EXACT [GOC:mah] +synonym: "cessation of mitotic cell cycle" EXACT [GOC:mah] +synonym: "termination of mitotic cell cycle" EXACT [GOC:mah] +is_a: GO:0007050 ! cell cycle arrest +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +created_by: mah +creation_date: 2010-09-10T02:56:30Z + +[Term] +id: GO:0071851 +name: mitotic G1 cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen." [GOC:vw] +synonym: "G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:vw] +is_a: GO:0071849 ! G1 cell cycle arrest in response to nitrogen starvation +is_a: GO:0071850 ! mitotic cell cycle arrest +created_by: mah +creation_date: 2010-09-10T02:58:09Z + +[Term] +id: GO:0071852 +name: fungal-type cell wall organization or biogenesis +namespace: biological_process +def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall." [GOC:mah] +synonym: "fungal-type cell wall organisation or biogenesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0071554 ! cell wall organization or biogenesis +created_by: mah +creation_date: 2010-09-10T03:07:55Z + +[Term] +id: GO:0071853 +name: fungal-type cell wall disassembly +namespace: biological_process +def: "A cellular process that results in the breakdown of a fungal-type cell wall." [GOC:mah] +is_a: GO:0031505 ! fungal-type cell wall organization +is_a: GO:0044277 ! cell wall disassembly +created_by: mah +creation_date: 2010-09-10T03:10:47Z + +[Term] +id: GO:0071854 +name: cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly +namespace: biological_process +def: "The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall." [GOC:mah] +is_a: GO:0070910 ! cell wall macromolecule catabolic process involved in cell wall disassembly +intersection_of: GO:0016998 ! cell wall macromolecule catabolic process +intersection_of: part_of GO:0071853 ! fungal-type cell wall disassembly +relationship: part_of GO:0071853 ! fungal-type cell wall disassembly +created_by: mah +creation_date: 2010-09-10T03:12:08Z + +[Term] +id: GO:0071855 +name: neuropeptide receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuropeptide receptor." [GOC:kmv, GOC:mah] +is_a: GO:0001664 ! G protein-coupled receptor binding +created_by: mah +creation_date: 2010-09-10T03:21:43Z + +[Term] +id: GO:0071857 +name: beta-endorphin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a beta-endorphin receptor." [GOC:kmv, GOC:mah] +is_a: GO:0071855 ! neuropeptide receptor binding +created_by: mah +creation_date: 2010-09-10T03:23:01Z + +[Term] +id: GO:0071858 +name: corazonin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a corazonin receptor." [GOC:kmv, GOC:mah] +is_a: GO:0071855 ! neuropeptide receptor binding +created_by: mah +creation_date: 2010-09-10T03:23:40Z + +[Term] +id: GO:0071859 +name: neuropeptide F receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a neuropeptide F receptor." [GOC:kmv, GOC:mah] +is_a: GO:0071855 ! neuropeptide receptor binding +created_by: mah +creation_date: 2010-09-10T03:23:56Z + +[Term] +id: GO:0071860 +name: proctolin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proctolin receptor." [GOC:kmv, GOC:mah] +is_a: GO:0071855 ! neuropeptide receptor binding +created_by: mah +creation_date: 2010-09-10T03:24:19Z + +[Term] +id: GO:0071861 +name: tachykinin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a tachykinin receptor." [GOC:kmv, GOC:mah] +is_a: GO:0071855 ! neuropeptide receptor binding +created_by: mah +creation_date: 2010-09-10T03:24:34Z + +[Term] +id: GO:0071863 +name: regulation of cell proliferation in bone marrow +namespace: biological_process +def: "A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow." [GOC:mah, GOC:yaf, PMID:17063141] +synonym: "regulation of bone marrow cell proliferation" EXACT [GOC:yaf] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071838 ! cell proliferation in bone marrow +relationship: regulates GO:0071838 ! cell proliferation in bone marrow +created_by: mah +creation_date: 2010-09-13T02:11:08Z + +[Term] +id: GO:0071864 +name: positive regulation of cell proliferation in bone marrow +namespace: biological_process +def: "A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow." [GOC:mah, GOC:yaf, PMID:17063141] +synonym: "activation of cell proliferation in bone marrow" NARROW [GOC:mah] +synonym: "positive regulation of bone marrow cell proliferation" EXACT [GOC:yaf] +synonym: "stimulation of cell proliferation in bone marrow" NARROW [GOC:mah] +synonym: "up regulation of cell proliferation in bone marrow" EXACT [GOC:mah] +synonym: "up-regulation of cell proliferation in bone marrow" EXACT [GOC:mah] +synonym: "upregulation of cell proliferation in bone marrow" EXACT [GOC:mah] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0071863 ! regulation of cell proliferation in bone marrow +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071838 ! cell proliferation in bone marrow +relationship: positively_regulates GO:0071838 ! cell proliferation in bone marrow +created_by: mah +creation_date: 2010-09-13T02:12:36Z + +[Term] +id: GO:0071865 +name: regulation of apoptotic process in bone marrow cell +namespace: biological_process +def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow." [GOC:mah, GOC:mtg_apoptosis, GOC:yaf, PMID:17063141] +synonym: "regulation of apoptosis in bone marrow" NARROW [] +synonym: "regulation of apoptotic process in bone marrow" EXACT [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071839 ! apoptotic process in bone marrow cell +relationship: regulates GO:0071839 ! apoptotic process in bone marrow cell +created_by: mah +creation_date: 2010-09-13T02:16:43Z + +[Term] +id: GO:0071866 +name: negative regulation of apoptotic process in bone marrow cell +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow." [GOC:mah, GOC:mtg_apoptosis, GOC:yaf, PMID:17063141] +synonym: "down regulation of apoptosis in bone marrow" EXACT [GOC:mah] +synonym: "down-regulation of apoptosis in bone marrow" EXACT [GOC:mah] +synonym: "downregulation of apoptosis in bone marrow" EXACT [GOC:mah] +synonym: "inhibition of apoptosis in bone marrow" NARROW [GOC:mah] +synonym: "negative regulation of apoptosis in bone marrow" NARROW [] +synonym: "negative regulation of apoptotic process in bone marrow" EXACT [] +synonym: "negative regulation of bone marrow cell apoptosis" EXACT [GOC:mah, GOC:yaf] +synonym: "negative regulation of bone marrow cell programmed cell death by apoptosis" EXACT [GOC:mah] +synonym: "negative regulation of killing of bone marrow cells" EXACT [GOC:mah] +synonym: "negative regulation of programmed cell death of bone marrow cells by apoptosis" EXACT [GOC:mah] +synonym: "negative regulation of programmed cell death, bone marrow cells" EXACT [GOC:mah] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:0071865 ! regulation of apoptotic process in bone marrow cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071839 ! apoptotic process in bone marrow cell +relationship: negatively_regulates GO:0071839 ! apoptotic process in bone marrow cell +created_by: mah +creation_date: 2010-09-13T02:17:38Z + +[Term] +id: GO:0071867 +name: response to monoamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] +synonym: "response to monoamine stimulus" EXACT [GOC:dos] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: mah +creation_date: 2010-09-13T02:36:37Z + +[Term] +id: GO:0071868 +name: cellular response to monoamine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0071867 ! response to monoamine +created_by: mah +creation_date: 2010-09-13T02:38:52Z + +[Term] +id: GO:0071869 +name: response to catecholamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] +synonym: "response to catecholamine stimulus" EXACT [GOC:dos] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0071867 ! response to monoamine +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2010-09-13T02:51:13Z + +[Term] +id: GO:0071870 +name: cellular response to catecholamine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071868 ! cellular response to monoamine stimulus +is_a: GO:0071869 ! response to catecholamine +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2010-09-13T02:54:50Z + +[Term] +id: GO:0071871 +name: response to epinephrine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system." [GOC:BHF, GOC:mah] +comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. +synonym: "response to adrenaline stimulus" EXACT [GOC:mah] +synonym: "response to epinephrine stimulus" EXACT [GOC:dos] +is_a: GO:0071869 ! response to catecholamine +created_by: mah +creation_date: 2010-09-13T03:27:48Z + +[Term] +id: GO:0071872 +name: cellular response to epinephrine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system." [GOC:BHF, GOC:mah] +comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. +synonym: "cellular response to adrenaline stimulus" EXACT [GOC:mah] +is_a: GO:0071870 ! cellular response to catecholamine stimulus +is_a: GO:0071871 ! response to epinephrine +created_by: mah +creation_date: 2010-09-13T03:31:40Z + +[Term] +id: GO:0071873 +name: response to norepinephrine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] +comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. +synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] +synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] +is_a: GO:0071869 ! response to catecholamine +created_by: mah +creation_date: 2010-09-13T03:31:53Z + +[Term] +id: GO:0071874 +name: cellular response to norepinephrine stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] +comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. +synonym: "cellular response to noradrenaline stimulus" EXACT [GOC:mah] +is_a: GO:0071870 ! cellular response to catecholamine stimulus +is_a: GO:0071873 ! response to norepinephrine +created_by: mah +creation_date: 2010-09-13T03:33:32Z + +[Term] +id: GO:0071875 +name: adrenergic receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands." [GOC:BHF] +synonym: "adrenergic receptor signalling pathway" EXACT [GOC:mah] +synonym: "adrenoceptor signaling pathway" EXACT [GOC:mah] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T03:44:44Z + +[Term] +id: GO:0071876 +name: obsolete initiation of adrenergic receptor signal transduction +namespace: biological_process +def: "OBSOLETE. A process of signal initiation in which epinephrine or norepinephrine causes activation of an adrenergic receptor." [GOC:BHF, GOC:mah] +comment: This term was made obsolete because the meaning of the term is ambiguous. +synonym: "initiation of adrenergic receptor signal transduction" EXACT [] +is_obsolete: true +consider: GO:0004935 +consider: GO:0005179 +consider: GO:0071872 +consider: GO:0071874 +consider: GO:0071875 +created_by: mah +creation_date: 2010-09-13T04:05:38Z + +[Term] +id: GO:0071877 +name: regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands." [GOC:BHF, GOC:mah] +synonym: "false" BROAD [] +synonym: "regulation of adrenergic receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071881 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway +relationship: regulates GO:0071881 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:12:10Z + +[Term] +id: GO:0071878 +name: negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands." [GOC:BHF, GOC:mah] +synonym: "false" BROAD [] +synonym: "negative regulation of adrenergic receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0106072 ! negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +relationship: negatively_regulates GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:15:34Z + +[Term] +id: GO:0071879 +name: positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands." [GOC:BHF, GOC:mah] +synonym: "positive regulation of adrenergic receptor signaling pathway" BROAD [] +synonym: "positive regulation of adrenergic receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071875 ! adrenergic receptor signaling pathway +relationship: positively_regulates GO:0071875 ! adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:15:57Z + +[Term] +id: GO:0071880 +name: adenylate cyclase-activating adrenergic receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:BHF, GOC:mah, GOC:signaling] +synonym: "activation of adenylate cyclase activity by adrenergic receptor signaling pathway" RELATED [GOC:signaling] +synonym: "activation of adenylate cyclase activity by adrenergic receptor signalling pathway" EXACT [GOC:mah] +synonym: "adrenergic receptor, adenylate cyclase activating pathway" EXACT [GOC:mah] +synonym: "adrenergic receptor, adenylyl cyclase activating pathway" EXACT [GOC:mah] +is_a: GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:0071875 ! adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:21:28Z + +[Term] +id: GO:0071881 +name: adenylate cyclase-inhibiting adrenergic receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP)." [GOC:BHF, GOC:mah, GOC:signaling] +synonym: "adrenergic receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:mah] +synonym: "adrenergic receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:mah] +synonym: "inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway" RELATED [GOC:signaling] +synonym: "inhibition of adenylate cyclase activity by adrenergic receptor signalling pathway" RELATED [GOC:mah] +is_a: GO:0007193 ! adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway +is_a: GO:0071875 ! adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:22:53Z + +[Term] +id: GO:0071882 +name: phospholipase C-activating adrenergic receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG)." [GOC:BHF, GOC:mah, GOC:signaling] +synonym: "activation of phospholipase C activity by adrenergic receptor signaling pathway" RELATED [GOC:bf] +synonym: "activation of phospholipase C activity by adrenergic receptor signalling pathway" RELATED [GOC:mah] +synonym: "adrenergic receptor, phospholipase C activating pathway" RELATED [GOC:mah] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0071875 ! adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:32:03Z + +[Term] +id: GO:0071883 +name: activation of MAPK activity by adrenergic receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, followed by the activation of a MAP kinase." [GOC:BHF, GOC:mah] +synonym: "activation of MAP kinase activity by adrenergic receptor signaling pathway" EXACT [GOC:mah] +synonym: "activation of MAP kinase activity by adrenergic receptor signalling pathway" EXACT [GOC:mah] +synonym: "activation of MAPK activity by adrenergic receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0000187 ! activation of MAPK activity +is_a: GO:0071875 ! adrenergic receptor signaling pathway +created_by: mah +creation_date: 2010-09-13T04:34:47Z + +[Term] +id: GO:0071885 +name: N-terminal protein N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser." [PMID:20481588] +synonym: "X-Pro-Lys N-terminal methyltransferase" NARROW [GOC:rn] +is_a: GO:0008276 ! protein methyltransferase activity +created_by: mah +creation_date: 2010-09-13T04:53:57Z + +[Term] +id: GO:0071886 +name: 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug." [GOC:yaf, PMID:19057895] +synonym: "(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding" EXACT [CHEBI:100436] +synonym: "1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding" EXACT [PMID:19057895] +synonym: "4-iodo-2,5-dimethoxyphenylisopropylamine binding" EXACT [PubChem_Compound:1229] +is_a: GO:0008144 ! drug binding +is_a: GO:0043176 ! amine binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: mah +creation_date: 2010-09-14T12:29:36Z + +[Term] +id: GO:0071887 +name: leukocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "leukocyte apoptosis" NARROW [] +is_a: GO:0006915 ! apoptotic process +created_by: mah +creation_date: 2010-09-14T12:44:09Z + +[Term] +id: GO:0071888 +name: macrophage apoptotic process +namespace: biological_process +def: "Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues." [CL:0000235, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). +synonym: "activation-induced cell death" RELATED [GOC:yaf] +synonym: "AICD" RELATED [GOC:yaf] +synonym: "macrophage apoptosis" NARROW [] +is_a: GO:0006925 ! inflammatory cell apoptotic process +is_a: GO:0033028 ! myeloid cell apoptotic process +is_a: GO:0071887 ! leukocyte apoptotic process +created_by: mah +creation_date: 2010-09-14T12:50:40Z + +[Term] +id: GO:0071889 +name: 14-3-3 protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins." [GOC:cna, GOC:mah, InterPro:IPR000308, PMID:15167810, PMID:19575580, PR:000003237] +is_a: GO:0005515 ! protein binding +created_by: mah +creation_date: 2010-09-14T01:21:50Z + +[Term] +id: GO:0071890 +name: bicarbonate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with bicarbonate (CHO3-) ions." [GOC:curators] +synonym: "hydrogencarbonate binding" EXACT [CHEBI:17544] +is_a: GO:0043168 ! anion binding +created_by: mah +creation_date: 2010-09-14T01:47:43Z + +[Term] +id: GO:0071891 +name: N-terminal peptidyl-proline dimethylation involved in translation +namespace: biological_process +def: "An N-terminal peptidyl-proline dimethylation process that contributes to translation." [GOC:mah] +is_a: GO:0018016 ! N-terminal peptidyl-proline dimethylation +intersection_of: GO:0018016 ! N-terminal peptidyl-proline dimethylation +intersection_of: part_of GO:0006412 ! translation +relationship: part_of GO:0006412 ! translation +created_by: mah +creation_date: 2010-09-14T02:19:40Z + +[Term] +id: GO:0071892 +name: thrombocyte activation +namespace: biological_process +def: "A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals." [GOC:lb, GOC:mah, PMID:10606877, PMID:15634265, PMID:20180901] +synonym: "blood coagulation, thrombocyte activation" EXACT [GOC:mah] +is_a: GO:0001775 ! cell activation +relationship: part_of GO:0007596 ! blood coagulation +created_by: mah +creation_date: 2010-09-14T03:06:33Z + +[Term] +id: GO:0071893 +name: BMP signaling pathway involved in nephric duct formation +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation." [GOC:mah, GOC:mtg_kidney_jan10] +synonym: "BMP signalling pathway involved in nephric duct formation" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: part_of GO:0072179 ! nephric duct formation +relationship: part_of GO:0072179 ! nephric duct formation +created_by: mah +creation_date: 2010-09-14T03:14:59Z + +[Term] +id: GO:0071894 +name: histone H2B conserved C-terminal lysine ubiquitination +namespace: biological_process +def: "A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals." [GOC:mah, GOC:vw] +synonym: "budding yeast H2B K123 ubiquitination" NARROW [GOC:vw] +synonym: "fission yeast H2B K119 ubiquitination" NARROW [GOC:vw] +synonym: "mammalian H2B K120 ubiquitination" NARROW [GOC:vw] +is_a: GO:0033523 ! histone H2B ubiquitination +created_by: mah +creation_date: 2010-09-14T03:43:46Z + +[Term] +id: GO:0071895 +name: odontoblast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin." [GOC:sl, PMID:20425127] +is_a: GO:0060563 ! neuroepithelial cell differentiation +created_by: mah +creation_date: 2010-09-14T04:00:40Z + +[Term] +id: GO:0071896 +name: protein localization to adherens junction +namespace: biological_process +alt_id: GO:1904696 +def: "Any process in which a protein is transported to, and/or maintained at the adherens junction." [GOC:aruk, GOC:bc, GOC:BHF, GOC:mah, PMID:26412237] +synonym: "protein localisation in adherens junction" EXACT [] +synonym: "protein localisation in cell-cell adherens junction" EXACT [] +synonym: "protein localisation to adherens junction" EXACT [GOC:mah] +synonym: "protein localisation to cell-cell adherens junction" EXACT [] +synonym: "protein localization in adherens junction" EXACT [] +synonym: "protein localization in cell-cell adherens junction" EXACT [] +synonym: "protein localization to cell-cell adherens junction" EXACT [] +is_a: GO:0150105 ! protein localization to cell-cell junction +created_by: mah +creation_date: 2010-09-14T04:03:27Z + +[Term] +id: GO:0071897 +name: DNA biosynthetic process +namespace: biological_process +def: "The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:mah] +synonym: "DNA anabolism" EXACT [GOC:mah] +synonym: "DNA biosynthesis" EXACT [GOC:mah] +synonym: "DNA formation" EXACT [GOC:mah] +synonym: "DNA synthesis" EXACT [GOC:mah] +is_a: GO:0006259 ! DNA metabolic process +is_a: GO:0034645 ! cellular macromolecule biosynthetic process +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +created_by: mah +creation_date: 2010-09-15T02:14:33Z + +[Term] +id: GO:0071898 +name: regulation of estrogen receptor binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor." [GOC:BHF, GOC:mah] +is_a: GO:0050789 ! regulation of biological process +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0030331 ! estrogen receptor binding +relationship: regulates GO:0030331 ! estrogen receptor binding +created_by: mah +creation_date: 2010-09-15T02:48:49Z + +[Term] +id: GO:0071899 +name: negative regulation of estrogen receptor binding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor." [GOC:BHF, GOC:mah] +is_a: GO:0071898 ! regulation of estrogen receptor binding +is_a: GO:1900121 ! negative regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030331 ! estrogen receptor binding +relationship: negatively_regulates GO:0030331 ! estrogen receptor binding +created_by: mah +creation_date: 2010-09-15T02:51:10Z + +[Term] +id: GO:0071900 +name: regulation of protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:mah] +is_a: GO:0045859 ! regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004674 ! protein serine/threonine kinase activity +relationship: regulates GO:0004674 ! protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-09-15T03:08:35Z + +[Term] +id: GO:0071901 +name: negative regulation of protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:BHF, GOC:mah] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004674 ! protein serine/threonine kinase activity +relationship: negatively_regulates GO:0004674 ! protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-09-15T03:09:43Z + +[Term] +id: GO:0071902 +name: positive regulation of protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:mah] +is_a: GO:0045860 ! positive regulation of protein kinase activity +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004674 ! protein serine/threonine kinase activity +relationship: positively_regulates GO:0004674 ! protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-09-15T03:09:57Z + +[Term] +id: GO:0071903 +name: protein N-linked N-acetylglucosaminylation via asparagine +namespace: biological_process +def: "A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue." [GOC:pr, RESID:AA0151] +synonym: "protein amino acid N-linked N-acetylglucosaminylation via asparagine" EXACT [GOC:bf] +xref: RESID:AA0151 +is_a: GO:0018279 ! protein N-linked glycosylation via asparagine +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: mah +creation_date: 2010-09-15T03:49:16Z + +[Term] +id: GO:0071904 +name: protein N-linked N-acetylgalactosaminylation via asparagine +namespace: biological_process +def: "A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue." [GOC:pr, RESID:AA0420] +synonym: "protein amino acid N-linked N-acetylgalactosaminylation via asparagine" EXACT [GOC:bf] +xref: RESID:AA0420 +is_a: GO:0018279 ! protein N-linked glycosylation via asparagine +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: mah +creation_date: 2010-09-15T03:52:28Z + +[Term] +id: GO:0071905 +name: protein N-linked glucosylation via asparagine +namespace: biological_process +def: "A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue." [GOC:pr, RESID:AA0421] +synonym: "protein amino acid N-linked glucosylation via asparagine" EXACT [GOC:bf] +xref: RESID:AA0421 +is_a: GO:0018279 ! protein N-linked glycosylation via asparagine +created_by: mah +creation_date: 2010-09-15T03:54:25Z + +[Term] +id: GO:0071906 +name: CRD domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins." [GOC:yaf, PMID:19460168] +synonym: "context dependent regulatory domain binding" EXACT [GOC:mah] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-09-21T04:08:53Z + +[Term] +id: GO:0071907 +name: determination of digestive tract left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:cvs] +synonym: "determination of gut left/right asymmetry" EXACT [GOC:cvs] +synonym: "determination of left/right asymmetry of the digestive tract" EXACT [GOC:cvs] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0048565 ! digestive tract development +created_by: mah +creation_date: 2010-09-22T10:14:29Z + +[Term] +id: GO:0071908 +name: determination of intestine left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism." [GOC:cvs] +is_a: GO:0071907 ! determination of digestive tract left/right asymmetry +created_by: mah +creation_date: 2010-09-22T10:24:33Z + +[Term] +id: GO:0071909 +name: determination of stomach left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism." [GOC:cvs] +is_a: GO:0071907 ! determination of digestive tract left/right asymmetry +relationship: part_of GO:0062094 ! stomach development +created_by: mah +creation_date: 2010-09-22T10:25:30Z + +[Term] +id: GO:0071910 +name: determination of liver left/right asymmetry +namespace: biological_process +def: "Determination of the asymmetric location of the liver with respect to the left and right halves of the organism." [GOC:cvs] +is_a: GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0001889 ! liver development +created_by: mah +creation_date: 2010-09-22T10:26:47Z + +[Term] +id: GO:0071911 +name: synchronous neurotransmitter secretion +namespace: biological_process +def: "Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion." [GOC:dsf, PMID:19477156, PMID:20643933] +is_a: GO:0007269 ! neurotransmitter secretion +created_by: mah +creation_date: 2010-09-22T01:38:36Z + +[Term] +id: GO:0071912 +name: asynchronous neurotransmitter secretion +namespace: biological_process +def: "Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion." [GOC:dsf, PMID:19477156, PMID:20643933] +is_a: GO:0007269 ! neurotransmitter secretion +created_by: mah +creation_date: 2010-09-22T01:45:35Z + +[Term] +id: GO:0071913 +name: citrate secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mah, GOC:mtg_transport, GOC:vw] +synonym: "citrate carrier activity" EXACT [GOC:mah] +is_a: GO:0005371 ! tricarboxylate secondary active transmembrane transporter activity +is_a: GO:0015137 ! citrate transmembrane transporter activity +created_by: mah +creation_date: 2010-09-22T02:18:54Z + +[Term] +id: GO:0071914 +name: prominosome +namespace: cellular_component +def: "An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known." [GOC:vesicles, PMID:15976444, PMID:17109118, PMID:17283184] +synonym: "prominin-containing extracellular membrane vesicle" EXACT [] +is_a: GO:1903561 ! extracellular vesicle +created_by: mah +creation_date: 2010-09-24T09:24:36Z + +[Term] +id: GO:0071915 +name: protein-lysine lysylation +namespace: biological_process +def: "The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)." [GOC:imk, GOC:jsg, PMID:20729861] +synonym: "protein amino acid lysylation" EXACT [GOC:imk] +is_a: GO:0018205 ! peptidyl-lysine modification +relationship: part_of GO:0072580 ! bacterial-type EF-P lysine modification +created_by: mah +creation_date: 2010-09-24T10:01:57Z + +[Term] +id: GO:0071916 +name: dipeptide transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0042936 +def: "Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond." [GOC:mah] +synonym: "dipeptide transporter activity" RELATED [] +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity +relationship: part_of GO:0035442 ! dipeptide transmembrane transport +created_by: mah +creation_date: 2010-09-24T10:32:36Z + +[Term] +id: GO:0071917 +name: triose-phosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a triose phosphate from one side of a membrane to the other." [GOC:mah, GOC:vw] +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:0035436 ! triose phosphate transmembrane transport +created_by: mah +creation_date: 2010-09-24T10:35:26Z + +[Term] +id: GO:0071918 +name: urea transmembrane transport +namespace: biological_process +def: "The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "urea membrane transport" EXACT [] +is_a: GO:0015840 ! urea transport +is_a: GO:0055085 ! transmembrane transport +created_by: mah +creation_date: 2010-09-24T10:41:36Z + +[Term] +id: GO:0071919 +name: G-quadruplex DNA formation +namespace: biological_process +def: "A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature." [GOC:sre, PMID:20098422] +synonym: "G quadruplex DNA formation" EXACT [GOC:mah] +synonym: "G quartet DNA formation" EXACT [GOC:mah] +synonym: "G-quartet DNA formation" EXACT [GOC:mah] +is_a: GO:0006259 ! DNA metabolic process +created_by: mah +creation_date: 2010-09-24T10:57:43Z + +[Term] +id: GO:0071920 +name: cleavage body +namespace: cellular_component +def: "A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing." [PMID:10564273, PMID:11598190, PMID:8654386] +is_a: GO:0016604 ! nuclear body +created_by: mah +creation_date: 2010-09-28T10:35:05Z + +[Term] +id: GO:0071921 +name: cohesin loading +namespace: biological_process +def: "The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA." [GOC:dph, GOC:mah, GOC:vw, PMID:10882066, PMID:17113138, PMID:26687354] +synonym: "cohesin association with chromatin" EXACT [GOC:lb] +synonym: "cohesin localisation to chromatin" EXACT [GOC:mah] +synonym: "cohesin localization to chromatin" EXACT [GOC:vw] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:0071168 ! protein localization to chromatin +relationship: part_of GO:0034085 ! establishment of sister chromatid cohesion +created_by: mah +creation_date: 2010-09-28T11:07:26Z + +[Term] +id: GO:0071922 +name: regulation of cohesin loading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:lb, GOC:mah, PMID:17113138] +synonym: "regulation of cohesin association with chromatin" EXACT [GOC:lb] +synonym: "regulation of cohesin localisation to chromatin" EXACT [GOC:mah] +synonym: "regulation of cohesin localization to chromatin" EXACT [GOC:vw] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +is_a: GO:0051101 ! regulation of DNA binding +is_a: GO:1905634 ! regulation of protein localization to chromatin +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071921 ! cohesin loading +relationship: regulates GO:0071921 ! cohesin loading +created_by: mah +creation_date: 2010-09-28T11:13:35Z + +[Term] +id: GO:0071923 +name: negative regulation of cohesin loading +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:lb, GOC:mah, PMID:17113138] +synonym: "negative regulation of cohesin association with chromatin" EXACT [GOC:lb] +synonym: "negative regulation of cohesin localisation to chromatin" EXACT [GOC:mah] +synonym: "negative regulation of cohesin localization to chromatin" RELATED [GOC:vw] +is_a: GO:0045875 ! negative regulation of sister chromatid cohesion +is_a: GO:0071922 ! regulation of cohesin loading +is_a: GO:0120186 ! negative regulation of protein localization to chromatin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071921 ! cohesin loading +relationship: negatively_regulates GO:0071921 ! cohesin loading +created_by: mah +creation_date: 2010-09-28T11:17:50Z + +[Term] +id: GO:0071924 +name: chemokine (C-C motif) ligand 22 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah, PMID:18832724] +synonym: "C-C motif chemokine 22 production" EXACT [GOC:mah] +synonym: "CCL-22 production" EXACT [GOC:mah] +synonym: "CCL22 production" EXACT [GOC:mah] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-09-28T11:33:13Z + +[Term] +id: GO:0071925 +name: thymic stromal lymphopoietin production +namespace: biological_process +def: "The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah, PMID:17129180] +synonym: "TSLP production" EXACT [GOC:mah] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-09-28T11:38:55Z + +[Term] +id: GO:0071926 +name: endocannabinoid signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol." [GOC:bf, GOC:mah, PMID:15550444] +synonym: "endocannabinoid signalling pathway" EXACT [GOC:mah] +is_a: GO:0038171 ! cannabinoid signaling pathway +created_by: mah +creation_date: 2010-09-28T11:52:03Z + +[Term] +id: GO:0071927 +name: octopamine signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor." [GOC:mah, PMID:15355245] +synonym: "octopamine signalling pathway" EXACT [GOC:mah] +is_a: GO:0007211 ! octopamine or tyramine signaling pathway +created_by: mah +creation_date: 2010-09-28T01:18:57Z + +[Term] +id: GO:0071928 +name: tyramine signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor." [GOC:mah, PMID:15355245] +synonym: "tyramine signalling pathway" EXACT [GOC:mah] +is_a: GO:0007211 ! octopamine or tyramine signaling pathway +created_by: mah +creation_date: 2010-09-28T01:20:10Z + +[Term] +id: GO:0071929 +name: alpha-tubulin acetylation +namespace: biological_process +def: "The addition of an acetyl group to the lysine 40 residue of alpha-tubulin." [GOC:kmv, PMID:17786050] +is_a: GO:0018393 ! internal peptidyl-lysine acetylation +created_by: mah +creation_date: 2010-09-28T01:46:38Z + +[Term] +id: GO:0071930 +name: negative regulation of transcription involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle." [GOC:mah, GOC:vw] +synonym: "negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle" RELATED [GOC:mah] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle" EXACT [GOC:mah] +is_a: GO:0000083 ! regulation of transcription involved in G1/S transition of mitotic cell cycle +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: part_of GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: mah +creation_date: 2010-09-29T11:12:11Z + +[Term] +id: GO:0071931 +name: positive regulation of transcription involved in G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle." [GOC:mah, GOC:vw] +synonym: "positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle" RELATED [GOC:mah] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle" EXACT [GOC:mah] +is_a: GO:0000083 ! regulation of transcription involved in G1/S transition of mitotic cell cycle +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: part_of GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: mah +creation_date: 2010-09-29T11:15:34Z + +[Term] +id: GO:0071932 +name: replication fork reversal +namespace: biological_process +def: "Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved." [PMID:19406929] +is_a: GO:0031297 ! replication fork processing +created_by: mah +creation_date: 2010-09-29T02:34:22Z + +[Term] +id: GO:0071933 +name: Arp2/3 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5)." [GOC:mah] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2010-09-29T02:48:41Z + +[Term] +id: GO:0071934 +name: thiamine transmembrane transport +namespace: biological_process +def: "The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "thiamin transmembrane transport" EXACT [GOC:mah] +synonym: "thiamine membrane transport" EXACT [] +synonym: "vitamin B1 transmembrane transport" EXACT [GOC:mah] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015888 ! thiamine transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:0072531 ! pyrimidine-containing compound transmembrane transport +created_by: mah +creation_date: 2010-09-29T02:59:39Z + +[Term] +id: GO:0071935 +name: octopamine signaling pathway involved in response to food +namespace: biological_process +def: "The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus." [GOC:mah, PMID:19609300] +synonym: "octopamine signalling pathway involved in response to food" EXACT [GOC:mah] +is_a: GO:0071927 ! octopamine signaling pathway +intersection_of: GO:0071927 ! octopamine signaling pathway +intersection_of: part_of GO:0032094 ! response to food +relationship: part_of GO:0032094 ! response to food +created_by: mah +creation_date: 2010-09-30T11:55:59Z + +[Term] +id: GO:0071936 +name: coreceptor activity involved in Wnt signaling pathway +namespace: molecular_function +def: "In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway." [GOC:BHF, GOC:mah] +synonym: "coreceptor activity involved in Wnt receptor signaling pathway" EXACT [] +synonym: "coreceptor activity involved in Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "coreceptor activity involved in Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "Wnt co-receptor activity" EXACT [GOC:bf] +is_a: GO:0015026 ! coreceptor activity +intersection_of: GO:0015026 ! coreceptor activity +intersection_of: part_of GO:0016055 ! Wnt signaling pathway +relationship: part_of GO:0016055 ! Wnt signaling pathway +created_by: mah +creation_date: 2010-09-30T03:54:34Z + +[Term] +id: GO:0071938 +name: vitamin A transport +namespace: biological_process +def: "The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid." [GOC:mah, PMID:16011460, PMID:1924551] +synonym: "vitamin A uptake and transport" RELATED [GOC:rs] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0034633 ! retinol transport +is_a: GO:0051180 ! vitamin transport +created_by: mah +creation_date: 2010-09-30T04:15:10Z + +[Term] +id: GO:0071939 +name: vitamin A import +namespace: biological_process +def: "The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid." [GOC:mah, PMID:16011460, PMID:1924551] +synonym: "vitamin A uptake" EXACT [GOC:mah, GOC:rs] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0071938 ! vitamin A transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: mah +creation_date: 2010-09-30T04:36:22Z + +[Term] +id: GO:0071940 +name: fungal-type cell wall assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall." [GOC:mah, GOC:vw, PMID:19646873] +synonym: "fungal-type cell wall formation" RELATED [GOC:mah] +is_a: GO:0031505 ! fungal-type cell wall organization +is_a: GO:0070726 ! cell wall assembly +relationship: part_of GO:0009272 ! fungal-type cell wall biogenesis +created_by: mah +creation_date: 2010-09-30T04:59:36Z + +[Term] +id: GO:0071941 +name: nitrogen cycle metabolic process +namespace: biological_process +def: "A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization." [GOC:mah, PMID:16675690, Wikipedia:Nitrogen_cycle] +subset: goslim_chembl +subset: goslim_generic +subset: goslim_pombe +xref: Wikipedia:Nitrogen_cycle +is_a: GO:0006807 ! nitrogen compound metabolic process +created_by: mah +creation_date: 2010-09-30T05:21:03Z + +[Term] +id: GO:0071942 +name: XPC complex +namespace: cellular_component +def: "A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2." [PMID:11279143, PMID:15964821, PMID:19941824] +is_a: GO:0000109 ! nucleotide-excision repair complex +created_by: mah +creation_date: 2010-10-01T11:09:36Z + +[Term] +id: GO:0071943 +name: Myc-Max complex +namespace: cellular_component +def: "A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max." [GOC:cna, PMID:16620027, PMID:16620031, PMID:20170194] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: mah +creation_date: 2010-10-01T11:56:17Z + +[Term] +id: GO:0071944 +name: cell periphery +namespace: cellular_component +def: "The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures." [GOC:mah] +subset: goslim_flybase_ribbon +is_a: GO:0110165 ! cellular anatomical entity +created_by: mah +creation_date: 2010-10-04T01:51:47Z + +[Term] +id: GO:0071945 +name: regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed +namespace: biological_process +def: "A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein." [GOC:cilia, GOC:jl, PMID:20371342] +synonym: "regulation of bacterial-type flagellar cell motility by regulation of motor speed" RELATED [] +synonym: "regulation of bacterial-type flagellum cell motility by regulation of motor speed" EXACT [] +synonym: "regulation of flagellar cell motility by regulation of motor speed" BROAD [] +is_a: GO:1902021 ! regulation of bacterial-type flagellum-dependent cell motility +created_by: mah +creation_date: 2010-10-05T04:10:27Z + +[Term] +id: GO:0071946 +name: cis-acting DNA replication termination +namespace: biological_process +def: "A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing." [GOC:vw, PMID:20850009] +synonym: "cis acting DNA replication termination" EXACT [GOC:vw] +is_a: GO:0071170 ! site-specific DNA replication termination +created_by: mah +creation_date: 2010-10-06T01:08:48Z + +[Term] +id: GO:0071947 +name: protein deubiquitination involved in ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism." [GOC:mah] +is_a: GO:0016579 ! protein deubiquitination +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process +intersection_of: GO:0016579 ! protein deubiquitination +intersection_of: part_of GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: part_of GO:0006511 ! ubiquitin-dependent protein catabolic process +created_by: mah +creation_date: 2010-10-06T02:06:10Z + +[Term] +id: GO:0071948 +name: activation-induced B cell apoptotic process +namespace: biological_process +def: "B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death." [GOC:mtg_apoptosis, GOC:tfm, PMID:11032170, PMID:19300454] +synonym: "activated B cell apoptosis" BROAD [GOC:tfm] +synonym: "activation-induced B cell apoptosis" NARROW [] +synonym: "activation-induced B-cell apoptosis" EXACT [GOC:tfm] +synonym: "activation-induced cell death of B cells" EXACT [GOC:tfm] +synonym: "activation-induced cell death of B lymphocytes" EXACT [GOC:tfm] +synonym: "activation-induced cell death of B-cells" EXACT [GOC:tfm] +synonym: "activation-induced cell death of B-lymphocytes" EXACT [GOC:tfm] +synonym: "AICD" BROAD [GOC:tfm] +synonym: "antigen-driven apoptosis" BROAD [GOC:tfm] +is_a: GO:0001783 ! B cell apoptotic process +created_by: mah +creation_date: 2010-10-06T02:47:46Z + +[Term] +id: GO:0071949 +name: FAD binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah] +synonym: "oxidized flavin adenine dinucleotide binding" EXACT [GOC:mah] +synonym: "oxidized flavine-adenine dinucleotide binding" EXACT [GOC:mah] +is_a: GO:0050660 ! flavin adenine dinucleotide binding +created_by: mah +creation_date: 2010-10-07T12:30:28Z + +[Term] +id: GO:0071950 +name: FADH2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah] +synonym: "reduced flavin adenine dinucleotide binding" EXACT [GOC:mah] +synonym: "reduced flavine-adenine dinucleotide binding" EXACT [GOC:mah] +is_a: GO:0050660 ! flavin adenine dinucleotide binding +created_by: mah +creation_date: 2010-10-07T12:31:34Z + +[Term] +id: GO:0071951 +name: conversion of methionyl-tRNA to N-formyl-methionyl-tRNA +namespace: biological_process +def: "The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet)." [GOC:jsg, PMID:5337045] +is_a: GO:0019988 ! charged-tRNA amino acid modification +created_by: mah +creation_date: 2010-10-08T11:54:38Z + +[Term] +id: GO:0071952 +name: conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA +namespace: biological_process +def: "The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA." [GOC:jsg, PMID:17351629, PMID:18559341] +comment: Note that this process has been observed in some archaeal and bacterial species. +is_a: GO:0019988 ! charged-tRNA amino acid modification +created_by: mah +creation_date: 2010-10-08T12:02:00Z + +[Term] +id: GO:0071953 +name: elastic fiber +namespace: cellular_component +def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] +synonym: "elastic fibre" EXACT [GOC:mah] +synonym: "elastin fiber" EXACT [GOC:BHF] +is_a: GO:0099512 ! supramolecular fiber +relationship: part_of GO:0031012 ! extracellular matrix +created_by: mah +creation_date: 2010-10-11T11:44:57Z + +[Term] +id: GO:0071954 +name: chemokine (C-C motif) ligand 11 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:mah, PMID:9600955] +synonym: "C-C motif chemokine 11 production" EXACT [GOC:mah] +synonym: "CCL-11 production" EXACT [GOC:mah] +synonym: "CCL11 production" EXACT [GOC:mah] +synonym: "eotaxin production" BROAD [GOC:mah] +synonym: "eotaxin-1 production" EXACT [GOC:mah] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2010-10-08T12:10:34Z + +[Term] +id: GO:0071955 +name: recycling endosome to Golgi transport +namespace: biological_process +def: "The directed movement of substances from recycling endosomes to the Golgi." [GOC:lb] +is_a: GO:0042147 ! retrograde transport, endosome to Golgi +is_a: GO:0048193 ! Golgi vesicle transport +created_by: mah +creation_date: 2010-10-08T01:19:00Z + +[Term] +id: GO:0071957 +name: old mitotic spindle pole body +namespace: cellular_component +def: "The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis." [GOC:mah, GOC:vw, PMID:15132994] +synonym: "old SPB" EXACT [GOC:mah] +is_a: GO:0044732 ! mitotic spindle pole body +created_by: mah +creation_date: 2011-06-01T02:32:10Z + +[Term] +id: GO:0071958 +name: new mitotic spindle pole body +namespace: cellular_component +def: "The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize." [GOC:mah, GOC:vw, PMID:15132994] +synonym: "new SPB" EXACT [GOC:mah] +is_a: GO:0044732 ! mitotic spindle pole body +created_by: mah +creation_date: 2011-06-01T02:34:34Z + +[Term] +id: GO:0071959 +name: maintenance of mitotic sister chromatid cohesion, arms +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle." [GOC:mah, PMID:1708436] +synonym: "maintenance of mitotic sister chromatin cohesion along arms" EXACT [GOC:mah] +synonym: "maintenance of sister chromatin cohesion along arms at mitosis" EXACT [GOC:mah] +is_a: GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: part_of GO:0071961 ! mitotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-01T04:08:43Z + +[Term] +id: GO:0071960 +name: maintenance of mitotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle." [GOC:mah, PMID:1708436] +synonym: "maintenance of centromeric mitotic sister chromatin cohesion" EXACT [GOC:mah] +synonym: "maintenance of mitotic sister chromatin cohesion at centromere" EXACT [GOC:mah] +synonym: "maintenance of sister chromatin cohesion at centromere at mitosis" EXACT [GOC:mah] +is_a: GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: part_of GO:0071962 ! mitotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-01T04:10:59Z + +[Term] +id: GO:0071961 +name: mitotic sister chromatid cohesion, arms +namespace: biological_process +def: "The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis." [GOC:mah] +synonym: "mitotic sister chromatid cohesion along arms" EXACT [GOC:mah] +synonym: "sister chromatid cohesion along arms at mitosis" EXACT [GOC:mah] +is_a: GO:0007064 ! mitotic sister chromatid cohesion +created_by: mah +creation_date: 2011-06-02T11:21:13Z + +[Term] +id: GO:0071962 +name: mitotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "The cell cycle process in which centromeres of sister chromatids are joined during mitosis." [GOC:mah] +synonym: "centromeric mitotic sister chromatin cohesion" EXACT [GOC:mah] +synonym: "mitotic sister chromatid cohesion at centromere" EXACT [GOC:mah] +synonym: "sister chromatid cohesion at centromere at mitosis" EXACT [GOC:mah] +is_a: GO:0007064 ! mitotic sister chromatid cohesion +is_a: GO:0070601 ! centromeric sister chromatid cohesion +created_by: mah +creation_date: 2011-06-02T11:24:17Z + +[Term] +id: GO:0071963 +name: establishment or maintenance of cell polarity regulating cell shape +namespace: biological_process +def: "Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell." [GOC:mah] +is_a: GO:0007163 ! establishment or maintenance of cell polarity +is_a: GO:0008360 ! regulation of cell shape +created_by: mah +creation_date: 2011-06-21T03:47:21Z + +[Term] +id: GO:0071964 +name: establishment of cell polarity regulating cell shape +namespace: biological_process +def: "Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell." [GOC:mah] +is_a: GO:0030010 ! establishment of cell polarity +is_a: GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-22T03:10:08Z + +[Term] +id: GO:0071965 +name: multicellular organismal locomotion +namespace: biological_process +def: "Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another." [GOC:mah] +is_a: GO:0040011 ! locomotion +is_a: GO:0050879 ! multicellular organismal movement +created_by: mah +creation_date: 2010-10-14T10:34:35Z + +[Term] +id: GO:0071966 +name: fungal-type cell wall polysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall." [GOC:mah] +is_a: GO:0010383 ! cell wall polysaccharide metabolic process +relationship: part_of GO:0071852 ! fungal-type cell wall organization or biogenesis +created_by: mah +creation_date: 2010-10-14T11:56:47Z + +[Term] +id: GO:0071967 +name: lipopolysaccharide core heptosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+." [MetaCyc:RXN0-5122] +synonym: "LPS core heptosyltransferase activity" EXACT [MetaCyc:LIPA-CORESYN-PWY] +xref: MetaCyc:RXN0-5122 +is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity +created_by: mah +creation_date: 2010-10-14T05:13:31Z + +[Term] +id: GO:0071968 +name: lipid A-core heptosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+." [MetaCyc:RXN0-5127] +xref: MetaCyc:RXN0-5127 +is_a: GO:0008920 ! lipopolysaccharide heptosyltransferase activity +created_by: mah +creation_date: 2010-10-14T05:15:22Z + +[Term] +id: GO:0071969 +name: fungal-type cell wall (1->3)-beta-D-glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi." [GOC:mah] +synonym: "fungal-type cell wall 1,3-beta-D-glucan metabolic process" EXACT [] +synonym: "fungal-type cell wall 1,3-beta-glucan metabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3 glucan metabolic process" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3 glucan metabolism" EXACT [GOC:mah] +is_a: GO:0034407 ! cell wall (1->3)-beta-D-glucan metabolic process +is_a: GO:0070879 ! fungal-type cell wall beta-glucan metabolic process +created_by: mah +creation_date: 2010-10-18T03:25:38Z + +[Term] +id: GO:0071970 +name: fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls." [GOC:mah] +synonym: "fungal-type cell wall 1,3-beta-D-glucan biosynthetic process" EXACT [] +synonym: "fungal-type cell wall 1,3-beta-glucan anabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-beta-glucan biosynthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-beta-glucan formation" EXACT [GOC:mah] +synonym: "fungal-type cell wall 1,3-beta-glucan synthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3-glucan anabolism" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3-glucan biosynthesis" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3-glucan biosynthetic process" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3-glucan formation" EXACT [GOC:mah] +synonym: "fungal-type cell wall beta-1,3-glucan synthesis" EXACT [GOC:mah] +is_a: GO:0034411 ! cell wall (1->3)-beta-D-glucan biosynthetic process +is_a: GO:0070880 ! fungal-type cell wall beta-glucan biosynthetic process +is_a: GO:0071969 ! fungal-type cell wall (1->3)-beta-D-glucan metabolic process +created_by: mah +creation_date: 2010-10-18T03:25:56Z + +[Term] +id: GO:0071971 +name: extracellular exosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458] +synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0097734 ! extracellular exosome biogenesis +created_by: mah +creation_date: 2010-10-18T03:44:18Z + +[Term] +id: GO:0071972 +name: peptidoglycan L,D-transpeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine." [MetaCyc:RXN-11349] +xref: MetaCyc:RXN-11349 +is_a: GO:0004185 ! serine-type carboxypeptidase activity +created_by: mah +creation_date: 2010-10-18T04:36:19Z + +[Term] +id: GO:0071973 +name: bacterial-type flagellum-dependent cell motility +namespace: biological_process +def: "Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope." [GOC:cilia, GOC:krc, GOC:mah] +subset: goslim_metagenomics +synonym: "bacterial-type flagellar cell motility" RELATED [] +synonym: "flagellin-based flagellar cell motility" EXACT [GOC:mah] +is_a: GO:0097588 ! archaeal or bacterial-type flagellum-dependent cell motility +created_by: mah +creation_date: 2010-10-21T12:00:53Z + +[Term] +id: GO:0071975 +name: cell swimming +namespace: biological_process +def: "Cell motility that results in the smooth movement of a cell through a liquid medium." [PMID:18461074] +synonym: "cell swimming motility" EXACT [GOC:mah] +is_a: GO:0048870 ! cell motility +created_by: mah +creation_date: 2010-10-21T02:31:34Z + +[Term] +id: GO:0071976 +name: cell gliding +namespace: biological_process +def: "Cell motility that results in the smooth movement of a cell along a solid surface." [PMID:18461074] +synonym: "cell gliding motility" EXACT [GOC:mah] +is_a: GO:0048870 ! cell motility +created_by: mah +creation_date: 2010-10-21T02:33:24Z + +[Term] +id: GO:0071977 +name: bacterial-type flagellum-dependent swimming motility +namespace: biological_process +def: "Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium." [GOC:cilia, PMID:18461074] +synonym: "bacterial-type flagellar swimming motility" RELATED [] +synonym: "bacterial-type flagellum-mediated cell swimming" EXACT [GOC:mah] +is_a: GO:0071973 ! bacterial-type flagellum-dependent cell motility +is_a: GO:0071975 ! cell swimming +created_by: mah +creation_date: 2010-10-21T02:58:51Z + +[Term] +id: GO:0071978 +name: bacterial-type flagellum-dependent swarming motility +namespace: biological_process +def: "Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria." [GOC:cilia, PMID:14527279, PMID:18461074] +synonym: "bacterial-type flagellar swarming motility" RELATED [] +synonym: "bacterial-type flagellum-mediated cell swarming" EXACT [GOC:mah] +is_a: GO:0071973 ! bacterial-type flagellum-dependent cell motility +created_by: mah +creation_date: 2010-10-21T03:00:14Z + +[Term] +id: GO:0071979 +name: cytoskeleton-mediated cell swimming +namespace: biological_process +def: "Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium." [PMID:18461074] +synonym: "cytoskeleton-mediated swimming motility" EXACT [GOC:mah] +is_a: GO:0071975 ! cell swimming +created_by: mah +creation_date: 2010-10-21T03:02:36Z + +[Term] +id: GO:0071980 +name: cell surface adhesin-mediated gliding motility +namespace: biological_process +def: "Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins." [PMID:18461074] +is_a: GO:0071976 ! cell gliding +created_by: mah +creation_date: 2010-10-21T03:03:44Z + +[Term] +id: GO:0071981 +name: exit from diapause +namespace: biological_process +def: "The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." [GOC:mah] +is_a: GO:0022611 ! dormancy process +created_by: mah +creation_date: 2010-10-21T04:45:40Z + +[Term] +id: GO:0071982 +name: maintenance of diapause +namespace: biological_process +def: "The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." [GOC:mah] +is_a: GO:0022611 ! dormancy process +created_by: mah +creation_date: 2010-10-21T04:46:32Z + +[Term] +id: GO:0071983 +name: exit from reproductive diapause +namespace: biological_process +def: "The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:mah] +is_a: GO:0071981 ! exit from diapause +created_by: mah +creation_date: 2010-10-21T04:48:12Z + +[Term] +id: GO:0071984 +name: maintenance of reproductive diapause +namespace: biological_process +def: "The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli." [GOC:mah] +is_a: GO:0071982 ! maintenance of diapause +created_by: mah +creation_date: 2010-10-21T04:49:28Z + +[Term] +id: GO:0071985 +name: multivesicular body sorting pathway +namespace: biological_process +def: "A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded." [GOC:mah, PMID:17603537] +is_a: GO:0016192 ! vesicle-mediated transport +created_by: mah +creation_date: 2010-10-22T12:04:16Z + +[Term] +id: GO:0071986 +name: Ragulator complex +namespace: cellular_component +def: "A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases." [GOC:krc, GOC:lb, GOC:vw, PMID:19177150, PMID:20381137, PMID:22980980, PMID:29199950] +synonym: "MAPKSP1/ROBLD3/C11orf59 complex" EXACT [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0031902 ! late endosome membrane +relationship: part_of GO:0045121 ! membrane raft +created_by: mah +creation_date: 2010-10-22T02:42:13Z + +[Term] +id: GO:0071987 +name: WD40-repeat domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain." [GOC:yaf, InterPro:IPR017986] +synonym: "beta-transducin repeat domain binding" EXACT [GOC:yaf] +synonym: "WD domain binding" EXACT [GOC:yaf] +is_a: GO:0019904 ! protein domain specific binding +created_by: mah +creation_date: 2010-10-22T02:53:29Z + +[Term] +id: GO:0071988 +name: protein localization to spindle pole body +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, the spindle pole body." [GOC:mah] +synonym: "protein localisation to spindle pole body" EXACT [GOC:mah] +is_a: GO:1905508 ! protein localization to microtubule organizing center +created_by: mah +creation_date: 2010-10-25T10:56:33Z + +[Term] +id: GO:0071989 +name: establishment of protein localization to spindle pole body +namespace: biological_process +def: "The directed movement of a protein to a specific location at the spindle pole body." [GOC:mah] +synonym: "establishment of protein localisation to spindle pole body" EXACT [GOC:mah] +is_a: GO:0071988 ! protein localization to spindle pole body +is_a: GO:0072594 ! establishment of protein localization to organelle +created_by: mah +creation_date: 2010-10-25T11:01:17Z + +[Term] +id: GO:0071990 +name: maintenance of protein location to spindle pole body +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere." [GOC:mah, GOC:vw] +synonym: "maintenance of protein location at spindle pole body" EXACT [] +synonym: "maintenance of protein location in spindle pole body" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005816 ! spindle pole body +relationship: occurs_in GO:0005816 ! spindle pole body +relationship: part_of GO:0051300 ! spindle pole body organization +relationship: part_of GO:0071988 ! protein localization to spindle pole body +created_by: mah +creation_date: 2010-10-25T11:02:31Z + +[Term] +id: GO:0071993 +name: phytochelatin transport +namespace: biological_process +def: "The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." [GOC:mah, ISBN:0198506732] +synonym: "cadystin transport" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +is_a: GO:0015833 ! peptide transport +created_by: mah +creation_date: 2010-10-25T01:57:55Z + +[Term] +id: GO:0071994 +name: phytochelatin transmembrane transport +namespace: biological_process +def: "The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." [GOC:mah, ISBN:0198506732] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "cadystin transmembrane transport" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "phytochelatin membrane transport" EXACT [] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0071993 ! phytochelatin transport +created_by: mah +creation_date: 2010-10-25T01:58:50Z + +[Term] +id: GO:0071995 +name: phytochelatin import into vacuole +namespace: biological_process +def: "The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." [GOC:mah, ISBN:0198506732] +synonym: "cadystin import into vacuole" RELATED [GOC:vw, Wikipedia:Phytochelatin#History] +synonym: "phytochelatin transport into vacuole" EXACT [GOC:vw] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0071994 ! phytochelatin transmembrane transport +created_by: mah +creation_date: 2010-10-25T02:01:59Z + +[Term] +id: GO:0071996 +name: glutathione transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of glutathione into the vacuole across the vacuolar membrane." [GOC:mah] +synonym: "glutathione transport into vacuole" EXACT [GOC:vw] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0034775 ! glutathione transmembrane transport +created_by: mah +creation_date: 2010-10-25T02:12:01Z + +[Term] +id: GO:0071998 +name: ascospore release from ascus +namespace: biological_process +def: "A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive." [DOI:10.1016/S0953-7562(96)80057-8, GOC:mah] +synonym: "ascospore liberation" EXACT [DOI:10.1016/S0953-7562(96)80057-8] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048869 ! cellular developmental process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0043935 ! sexual sporulation resulting in formation of a cellular spore +created_by: mah +creation_date: 2010-10-25T03:41:44Z + +[Term] +id: GO:0071999 +name: extracellular polysaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures." [GOC:mah, GOC:vw] +synonym: "extracellular polysaccharide breakdown" EXACT [GOC:mah] +synonym: "extracellular polysaccharide catabolism" EXACT [GOC:mah] +synonym: "extracellular polysaccharide degradation" EXACT [GOC:mah] +is_a: GO:0044247 ! cellular polysaccharide catabolic process +is_a: GO:0046379 ! extracellular polysaccharide metabolic process +created_by: mah +creation_date: 2010-10-25T05:11:25Z + +[Term] +id: GO:0072000 +name: extracellular polysaccharide catabolic process involved in ascospore release from ascus +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus." [GOC:mah, GOC:vw] +synonym: "ascus catabolic process" RELATED [GOC:vw] +synonym: "ascus endolysis" RELATED [GOC:vw] +synonym: "extracellular polysaccharide breakdown involved in ascospore release from ascus" EXACT [GOC:mah] +synonym: "extracellular polysaccharide catabolism involved in ascospore release from ascus" EXACT [GOC:mah] +synonym: "extracellular polysaccharide degradation involved in ascospore release from ascus" EXACT [GOC:mah] +is_a: GO:0071999 ! extracellular polysaccharide catabolic process +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0071999 ! extracellular polysaccharide catabolic process +intersection_of: part_of GO:0071998 ! ascospore release from ascus +relationship: part_of GO:0071998 ! ascospore release from ascus +created_by: mah +creation_date: 2010-10-25T05:30:41Z + +[Term] +id: GO:0072001 +name: renal system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System] +subset: gocheck_do_not_annotate +synonym: "urinary system development" BROAD [GOC:yaf] +synonym: "urinary tract development" BROAD [GOC:yaf, PMID:17881463] +is_a: GO:0048731 ! system development +relationship: part_of GO:0001655 ! urogenital system development +created_by: mah +creation_date: 2010-01-25T10:31:00Z + +[Term] +id: GO:0072002 +name: Malpighian tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut." [FBbt:00005786, GOC:mtg_kidney_jan10, PMID:19783135] +is_a: GO:0048513 ! animal organ development +is_a: GO:0061326 ! renal tubule development +created_by: mah +creation_date: 2010-01-25T10:54:30Z + +[Term] +id: GO:0072003 +name: kidney rudiment formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +synonym: "kidney anlage formation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060993 ! kidney morphogenesis +created_by: mah +creation_date: 2010-01-25T11:18:58Z + +[Term] +id: GO:0072004 +name: kidney field specification +namespace: biological_process +def: "The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop." [GOC:mtg_kidney_jan10] +synonym: "specification of kidney anlage" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0010092 ! specification of animal organ identity +is_a: GO:0061004 ! pattern specification involved in kidney development +relationship: part_of GO:0072003 ! kidney rudiment formation +created_by: mah +creation_date: 2010-01-25T11:24:33Z + +[Term] +id: GO:0072005 +name: maintenance of kidney identity +namespace: biological_process +def: "The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:mtg_kidney_jan10] +synonym: "maintenance of kidney anlage identity" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0048496 ! maintenance of animal organ identity +relationship: part_of GO:0072003 ! kidney rudiment formation +created_by: mah +creation_date: 2010-01-25T11:57:41Z + +[Term] +id: GO:0072006 +name: nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] +synonym: "nephrogenesis" RELATED [GOC:rph] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T01:37:16Z + +[Term] +id: GO:0072007 +name: mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +is_a: GO:1904238 ! pericyte cell differentiation +created_by: mah +creation_date: 2010-01-25T01:59:09Z + +[Term] +id: GO:0072008 +name: glomerular mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +is_a: GO:0072007 ! mesangial cell differentiation +relationship: part_of GO:0072109 ! glomerular mesangium development +created_by: mah +creation_date: 2010-01-25T01:59:33Z + +[Term] +id: GO:0072009 +name: nephron epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0072073 ! kidney epithelium development +relationship: part_of GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T02:01:39Z + +[Term] +id: GO:0072010 +name: glomerular epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +relationship: part_of GO:0032835 ! glomerulus development +created_by: mah +creation_date: 2010-01-25T02:02:14Z + +[Term] +id: GO:0072011 +name: glomerular endothelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0003158 ! endothelium development +is_a: GO:0072010 ! glomerular epithelium development +relationship: part_of GO:0072012 ! glomerulus vasculature development +created_by: mah +creation_date: 2010-01-25T02:02:57Z + +[Term] +id: GO:0072012 +name: glomerulus vasculature development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus." [GOC:mtg_kidney_jan10] +synonym: "glomerulus capillary development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0001568 ! blood vessel development +is_a: GO:0061440 ! kidney vasculature development +relationship: part_of GO:0032835 ! glomerulus development +created_by: mah +creation_date: 2010-01-25T02:05:04Z + +[Term] +id: GO:0072013 +name: glomus development +namespace: biological_process +def: "The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment." [GOC:mtg_kidney_jan10, PMID:10572058, PMID:15647339, PMID:9268568, XAO:0000318] +synonym: "pronephric glomus development" EXACT [GOC:mtg_kidney_jan10, PMID:15895368] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048793 ! pronephros development +created_by: mah +creation_date: 2010-01-25T02:23:19Z + +[Term] +id: GO:0072014 +name: proximal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-01-25T02:33:46Z + +[Term] +id: GO:0072015 +name: glomerular visceral epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells." [GOC:mtg_kidney_jan10] +synonym: "podocyte development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072310 ! glomerular epithelial cell development +relationship: part_of GO:0072112 ! glomerular visceral epithelial cell differentiation +created_by: mah +creation_date: 2010-01-25T02:12:45Z + +[Term] +id: GO:0072016 +name: glomerular parietal epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +synonym: "Bowman's capsule development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072310 ! glomerular epithelial cell development +relationship: part_of GO:0072139 ! glomerular parietal epithelial cell differentiation +created_by: mah +creation_date: 2010-01-25T02:13:16Z + +[Term] +id: GO:0072017 +name: distal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-01-25T02:34:19Z + +[Term] +id: GO:0072019 +name: proximal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0072014 ! proximal tubule development +created_by: mah +creation_date: 2010-01-25T02:35:35Z + +[Term] +id: GO:0072020 +name: proximal straight tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule." [GOC:mtg_kidney_jan10] +synonym: "S3 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0072014 ! proximal tubule development +created_by: mah +creation_date: 2010-01-25T02:36:14Z + +[Term] +id: GO:0072021 +name: ascending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0072070 ! loop of Henle development +created_by: mah +creation_date: 2010-01-25T02:37:13Z + +[Term] +id: GO:0072022 +name: descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0072070 ! loop of Henle development +created_by: mah +creation_date: 2010-01-25T02:37:47Z + +[Term] +id: GO:0072023 +name: thick ascending limb development +namespace: biological_process +alt_id: GO:0072026 +def: "The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule." [GOC:mtg_kidney_jan10] +synonym: "TAL development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0072017 ! distal tubule development +created_by: mah +creation_date: 2010-01-25T02:39:51Z + +[Term] +id: GO:0072024 +name: macula densa development +namespace: biological_process +def: "The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +relationship: part_of GO:0072051 ! juxtaglomerular apparatus development +created_by: mah +creation_date: 2010-01-25T02:40:15Z + +[Term] +id: GO:0072025 +name: distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +relationship: part_of GO:0072017 ! distal tubule development +created_by: mah +creation_date: 2010-01-25T02:40:45Z + +[Term] +id: GO:0072027 +name: connecting tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct." [GOC:mtg_kidney_jan10] +synonym: "connecting duct development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-01-25T02:42:05Z + +[Term] +id: GO:0072028 +name: nephron morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060993 ! kidney morphogenesis +relationship: part_of GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T02:45:52Z + +[Term] +id: GO:0072029 +name: long nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla." [GOC:mtg_kidney_jan10] +synonym: "juxtamedullary nephron development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T02:49:08Z + +[Term] +id: GO:0072030 +name: short nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb." [GOC:mtg_kidney_jan10] +is_a: GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T02:49:32Z + +[Term] +id: GO:0072031 +name: proximal convoluted tubule segment 1 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes." [GOC:mtg_kidney_jan10, MA:0002612] +synonym: "S1 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0072019 ! proximal convoluted tubule development +created_by: mah +creation_date: 2010-01-25T02:55:57Z + +[Term] +id: GO:0072032 +name: proximal convoluted tubule segment 2 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride." [GOC:mtg_kidney_jan10, MA:0002613] +synonym: "S2 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0072019 ! proximal convoluted tubule development +created_by: mah +creation_date: 2010-01-25T02:56:36Z + +[Term] +id: GO:0072033 +name: renal vesicle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] +synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0072077 ! renal vesicle morphogenesis +created_by: mah +creation_date: 2010-01-25T02:57:03Z + +[Term] +id: GO:0072034 +name: renal vesicle induction +namespace: biological_process +def: "Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle." [GOC:mtg_kidney_jan10] +synonym: "nephron induction" EXACT [GOC:mtg_kidney_jan10] +synonym: "positive regulation of nephron formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0031128 ! developmental induction +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +relationship: positively_regulates GO:0072033 ! renal vesicle formation +created_by: mah +creation_date: 2010-01-25T02:58:18Z + +[Term] +id: GO:0072035 +name: pre-tubular aggregate formation +namespace: biological_process +def: "The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney." [GOC:mtg_kidney_jan10] +synonym: "mesenchymal cell condensation involved in renal vesicle formation" EXACT [GOC:mtg_kidney_jan10] +synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0072033 ! renal vesicle formation +created_by: mah +creation_date: 2010-01-25T03:03:10Z + +[Term] +id: GO:0072036 +name: mesenchymal to epithelial transition involved in renal vesicle formation +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +is_a: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: part_of GO:0072033 ! renal vesicle formation +relationship: part_of GO:0072033 ! renal vesicle formation +created_by: mah +creation_date: 2010-01-25T03:04:24Z + +[Term] +id: GO:0072037 +name: mesenchymal stem cell differentiation involved in nephron morphogenesis +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +is_a: GO:0072497 ! mesenchymal stem cell differentiation +intersection_of: GO:0072497 ! mesenchymal stem cell differentiation +intersection_of: part_of GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:07:39Z + +[Term] +id: GO:0072038 +name: mesenchymal stem cell maintenance involved in nephron morphogenesis +namespace: biological_process +def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0035019 ! somatic stem cell population maintenance +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:08:05Z + +[Term] +id: GO:0072039 +name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +namespace: biological_process +def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] +synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] +is_a: GO:0090183 ! regulation of kidney development +is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis +is_a: GO:1904672 ! regulation of somatic stem cell population maintenance +is_a: GO:2000027 ! regulation of animal organ morphogenesis +is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +relationship: regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis +relationship: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:08:34Z + +[Term] +id: GO:0072040 +name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +namespace: biological_process +def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] +synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] +is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis +is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance +is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +relationship: negatively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis +relationship: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:09:30Z + +[Term] +id: GO:0072041 +name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +namespace: biological_process +def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] +synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] +is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis +is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance +is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +relationship: positively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis +relationship: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:10:32Z + +[Term] +id: GO:0072042 +name: regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10] +is_a: GO:1902460 ! regulation of mesenchymal stem cell proliferation +relationship: regulates GO:0072090 ! mesenchymal stem cell proliferation involved in nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:11:26Z + +[Term] +id: GO:0072043 +name: regulation of pre-tubular aggregate formation by cell-cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney." [GOC:mtg_kidney_jan10] +synonym: "regulation of pre-tubular aggregate formation by cell-cell signalling" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0090183 ! regulation of kidney development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072035 ! pre-tubular aggregate formation +relationship: regulates GO:0072035 ! pre-tubular aggregate formation +created_by: mah +creation_date: 2010-01-25T03:12:03Z + +[Term] +id: GO:0072044 +name: collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T03:18:06Z + +[Term] +id: GO:0072045 +name: convergent extension involved in nephron morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0060029 ! convergent extension involved in organogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:22:47Z + +[Term] +id: GO:0072046 +name: establishment of planar polarity involved in nephron morphogenesis +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10] +synonym: "establishment of planar cell polarity involved in nephron morphogenesis" NARROW [GOC:mtg_kidney_jan10] +is_a: GO:0001736 ! establishment of planar polarity +intersection_of: GO:0001736 ! establishment of planar polarity +intersection_of: part_of GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:24:04Z + +[Term] +id: GO:0072047 +name: proximal/distal pattern formation involved in nephron development +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)." [GOC:mtg_kidney_jan10] +synonym: "proximal-distal pattern formation involved in nephron development" EXACT [GOC:mtg_kidney_jan10] +synonym: "proximal/distal nephron patterning" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0009954 ! proximal/distal pattern formation +is_a: GO:0061004 ! pattern specification involved in kidney development +intersection_of: GO:0009954 ! proximal/distal pattern formation +intersection_of: part_of GO:0072006 ! nephron development +relationship: part_of GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T03:30:48Z + +[Term] +id: GO:0072048 +name: renal system pattern specification +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10] +synonym: "renal system pattern formation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0072001 ! renal system development +created_by: mah +creation_date: 2010-01-25T03:31:51Z + +[Term] +id: GO:0072049 +name: comma-shaped body morphogenesis +namespace: biological_process +def: "The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:44:48Z + +[Term] +id: GO:0072050 +name: S-shaped body morphogenesis +namespace: biological_process +def: "The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-01-25T03:45:19Z + +[Term] +id: GO:0072051 +name: juxtaglomerular apparatus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T03:52:23Z + +[Term] +id: GO:0072052 +name: juxtaglomerulus cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +relationship: part_of GO:0072051 ! juxtaglomerular apparatus development +created_by: mah +creation_date: 2010-01-25T03:58:01Z + +[Term] +id: GO:0072053 +name: renal inner medulla development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney." [GOC:mtg_kidney_jan10] +synonym: "inner renal medulla development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T03:59:37Z + +[Term] +id: GO:0072054 +name: renal outer medulla development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla." [GOC:mtg_kidney_jan10] +synonym: "outer renal medulla development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T04:00:42Z + +[Term] +id: GO:0072055 +name: renal cortex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T04:01:12Z + +[Term] +id: GO:0072056 +name: pyramid development +namespace: biological_process +def: "The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts." [GOC:mtg_kidney_jan10] +synonym: "kidney pyramid development" EXACT [GOC:mah] +synonym: "pyramids development" EXACT [GOC:mah] +synonym: "renal medulla development" EXACT [GOC:mah] +synonym: "renal pyramid development" EXACT [GOC:mah] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T04:01:36Z + +[Term] +id: GO:0072057 +name: inner stripe development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0072054 ! renal outer medulla development +created_by: mah +creation_date: 2010-01-25T04:01:58Z + +[Term] +id: GO:0072058 +name: outer stripe development +namespace: biological_process +def: "The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0072054 ! renal outer medulla development +created_by: mah +creation_date: 2010-01-25T04:02:56Z + +[Term] +id: GO:0072059 +name: cortical collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] +is_a: GO:0048856 ! anatomical structure development +created_by: mah +creation_date: 2010-01-25T04:07:07Z + +[Term] +id: GO:0072060 +name: outer medullary collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla." [GOC:mtg_kidney_jan10] +is_a: GO:0072044 ! collecting duct development +created_by: mah +creation_date: 2010-01-25T04:08:18Z + +[Term] +id: GO:0072061 +name: inner medullary collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla." [GOC:mtg_kidney_jan10] +is_a: GO:0072044 ! collecting duct development +created_by: mah +creation_date: 2010-01-25T04:08:45Z + +[Term] +id: GO:0072062 +name: proximal convoluted tubule segment 1 cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "S1 cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +relationship: part_of GO:0072031 ! proximal convoluted tubule segment 1 development +created_by: mah +creation_date: 2010-01-25T04:11:17Z + +[Term] +id: GO:0072063 +name: short descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +is_a: GO:0072022 ! descending thin limb development +relationship: part_of GO:0072030 ! short nephron development +created_by: mah +creation_date: 2010-01-25T04:12:39Z + +[Term] +id: GO:0072064 +name: long descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +is_a: GO:0072022 ! descending thin limb development +relationship: part_of GO:0072029 ! long nephron development +created_by: mah +creation_date: 2010-01-25T04:13:17Z + +[Term] +id: GO:0072065 +name: long descending thin limb bend development +namespace: biological_process +def: "The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0072064 ! long descending thin limb development +created_by: mah +creation_date: 2010-01-25T04:13:38Z + +[Term] +id: GO:0072066 +name: prebend segment development +namespace: biological_process +def: "The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +relationship: part_of GO:0072022 ! descending thin limb development +created_by: mah +creation_date: 2010-01-25T04:14:02Z + +[Term] +id: GO:0072067 +name: early distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +relationship: part_of GO:0072025 ! distal convoluted tubule development +created_by: mah +creation_date: 2010-01-25T04:15:17Z + +[Term] +id: GO:0072068 +name: late distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +relationship: part_of GO:0072025 ! distal convoluted tubule development +created_by: mah +creation_date: 2010-01-25T04:15:50Z + +[Term] +id: GO:0072069 +name: DCT cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "distal convoluted tubule cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +relationship: part_of GO:0072025 ! distal convoluted tubule development +created_by: mah +creation_date: 2010-01-25T04:17:22Z + +[Term] +id: GO:0072070 +name: loop of Henle development +namespace: biological_process +alt_id: GO:0072018 +def: "The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule." [GOC:mtg_kidney_jan10] +synonym: "intermediate tubule development" EXACT [] +is_a: GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-01-25T04:20:27Z + +[Term] +id: GO:0072071 +name: kidney interstitial fibroblast differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +created_by: mah +creation_date: 2010-01-25T04:34:31Z + +[Term] +id: GO:0072072 +name: kidney stroma development +namespace: biological_process +def: "The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0061448 ! connective tissue development +is_a: GO:0072074 ! kidney mesenchyme development +created_by: mah +creation_date: 2010-01-25T04:35:36Z + +[Term] +id: GO:0072073 +name: kidney epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T04:37:42Z + +[Term] +id: GO:0072074 +name: kidney mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0060485 ! mesenchyme development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-01-25T04:39:04Z + +[Term] +id: GO:0072075 +name: metanephric mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072074 ! kidney mesenchyme development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-01-25T04:40:11Z + +[Term] +id: GO:0072076 +name: nephrogenic mesenchyme development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0072074 ! kidney mesenchyme development +relationship: part_of GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-01-25T04:40:44Z + +[Term] +id: GO:0072077 +name: renal vesicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0072087 ! renal vesicle development +relationship: part_of GO:0072088 ! nephron epithelium morphogenesis +created_by: mah +creation_date: 2010-02-01T02:21:06Z + +[Term] +id: GO:0072078 +name: nephron tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0061333 ! renal tubule morphogenesis +is_a: GO:0072088 ! nephron epithelium morphogenesis +relationship: part_of GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-02-01T02:25:14Z + +[Term] +id: GO:0072079 +name: nephron tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0001838 ! embryonic epithelial tube formation +relationship: part_of GO:0072078 ! nephron tubule morphogenesis +created_by: mah +creation_date: 2010-02-01T02:29:26Z + +[Term] +id: GO:0072080 +name: nephron tubule development +namespace: biological_process +def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0061326 ! renal tubule development +is_a: GO:0072009 ! nephron epithelium development +created_by: mah +creation_date: 2010-02-01T02:32:12Z + +[Term] +id: GO:0072081 +name: specification of nephron tubule identity +namespace: biological_process +def: "The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0007379 ! segment specification +is_a: GO:0061004 ! pattern specification involved in kidney development +relationship: part_of GO:0072047 ! proximal/distal pattern formation involved in nephron development +relationship: part_of GO:0072079 ! nephron tubule formation +created_by: mah +creation_date: 2010-02-01T02:42:34Z + +[Term] +id: GO:0072082 +name: specification of proximal tubule identity +namespace: biological_process +def: "The process in which the proximal tubule of the kidney nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0072158 ! proximal tubule morphogenesis +created_by: mah +creation_date: 2010-02-01T02:44:34Z + +[Term] +id: GO:0072084 +name: specification of distal tubule identity +namespace: biological_process +def: "The process in which the distal tubule of the kidney nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0072156 ! distal tubule morphogenesis +created_by: mah +creation_date: 2010-02-01T02:47:53Z + +[Term] +id: GO:0072085 +name: specification of connecting tubule identity +namespace: biological_process +def: "The process in which the connecting tubule of the kidney nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0072027 ! connecting tubule development +created_by: mah +creation_date: 2010-02-01T02:49:11Z + +[Term] +id: GO:0072086 +name: specification of loop of Henle identity +namespace: biological_process +alt_id: GO:0072083 +def: "The process in which the loop of Henle of the kidney nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "specification of intermediate tubule identity" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0072070 ! loop of Henle development +created_by: mah +creation_date: 2010-02-01T02:49:35Z + +[Term] +id: GO:0072087 +name: renal vesicle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072073 ! kidney epithelium development +relationship: part_of GO:0072009 ! nephron epithelium development +created_by: mah +creation_date: 2010-02-08T01:18:31Z + +[Term] +id: GO:0072088 +name: nephron epithelium morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0072009 ! nephron epithelium development +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: mah +creation_date: 2010-02-08T01:19:06Z + +[Term] +id: GO:0072089 +name: stem cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] +is_a: GO:0008283 ! cell population proliferation +relationship: has_part GO:0017145 ! stem cell division +created_by: mah +creation_date: 2010-02-08T02:03:36Z + +[Term] +id: GO:0072090 +name: mesenchymal stem cell proliferation involved in nephron morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0097168 ! mesenchymal stem cell proliferation +created_by: mah +creation_date: 2010-02-08T02:05:54Z + +[Term] +id: GO:0072091 +name: regulation of stem cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072089 ! stem cell proliferation +relationship: regulates GO:0072089 ! stem cell proliferation +created_by: mah +creation_date: 2010-02-08T02:09:03Z + +[Term] +id: GO:0072092 +name: ureteric bud invasion +namespace: biological_process +def: "The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0060677 ! ureteric bud elongation +relationship: part_of GO:0072093 ! metanephric renal vesicle formation +created_by: mah +creation_date: 2010-02-10T01:15:13Z + +[Term] +id: GO:0072093 +name: metanephric renal vesicle formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072033 ! renal vesicle formation +relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis +created_by: mah +creation_date: 2010-02-10T01:17:11Z + +[Term] +id: GO:0072094 +name: metanephric renal vesicle induction +namespace: biological_process +def: "Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] +synonym: "positive regulation of metanephros formation" BROAD [GOC:mtg_kidney_jan10] +is_a: GO:0072034 ! renal vesicle induction +is_a: GO:0072216 ! positive regulation of metanephros development +relationship: positively_regulates GO:0072093 ! metanephric renal vesicle formation +created_by: mah +creation_date: 2010-02-10T01:23:20Z + +[Term] +id: GO:0072095 +name: regulation of branch elongation involved in ureteric bud branching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis." [GOC:mtg_kidney_jan10] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060681 ! branch elongation involved in ureteric bud branching +relationship: regulates GO:0060681 ! branch elongation involved in ureteric bud branching +created_by: mah +creation_date: 2010-02-10T01:41:18Z + +[Term] +id: GO:0072096 +name: negative regulation of branch elongation involved in ureteric bud branching +namespace: biological_process +def: "Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis." [GOC:mtg_kidney_jan10] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0072095 ! regulation of branch elongation involved in ureteric bud branching +is_a: GO:0090191 ! negative regulation of branching involved in ureteric bud morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060681 ! branch elongation involved in ureteric bud branching +relationship: negatively_regulates GO:0060681 ! branch elongation involved in ureteric bud branching +created_by: mah +creation_date: 2010-02-10T01:52:09Z + +[Term] +id: GO:0072097 +name: negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis." [GOC:mtg_kidney_jan10] +synonym: "negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +is_a: GO:0072096 ! negative regulation of branch elongation involved in ureteric bud branching +intersection_of: GO:0030509 ! BMP signaling pathway +intersection_of: negatively_regulates GO:0060681 ! branch elongation involved in ureteric bud branching +created_by: mah +creation_date: 2010-02-10T02:00:34Z + +[Term] +id: GO:0072098 +name: anterior/posterior pattern specification involved in kidney development +namespace: biological_process +def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] +synonym: "anterior/posterior pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] +synonym: "kidney anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] +synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0009952 ! anterior/posterior pattern specification +is_a: GO:0061004 ! pattern specification involved in kidney development +intersection_of: GO:0009952 ! anterior/posterior pattern specification +intersection_of: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-02-10T02:06:24Z + +[Term] +id: GO:0072099 +name: anterior/posterior pattern specification involved in ureteric bud development +namespace: biological_process +def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] +synonym: "ureteric bud anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0061227 ! pattern specification involved in mesonephros development +is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development +intersection_of: GO:0009952 ! anterior/posterior pattern specification +intersection_of: part_of GO:0001657 ! ureteric bud development +relationship: part_of GO:0001657 ! ureteric bud development +created_by: mah +creation_date: 2010-02-10T02:12:09Z + +[Term] +id: GO:0072100 +name: specification of ureteric bud anterior/posterior symmetry +namespace: biological_process +def: "The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis." [GOC:mtg_kidney_jan10] +synonym: "specification of ureteric bud anterior/posterior asymmetry" EXACT [GOC:dph] +is_a: GO:0009799 ! specification of symmetry +is_a: GO:0072099 ! anterior/posterior pattern specification involved in ureteric bud development +created_by: mah +creation_date: 2010-02-10T02:18:16Z + +[Term] +id: GO:0072101 +name: specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway +namespace: biological_process +def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis." [GOC:mtg_kidney_jan10] +synonym: "specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway" EXACT [GOC:dph] +synonym: "specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway" EXACT [GOC:mah] +is_a: GO:0030509 ! BMP signaling pathway +is_a: GO:0072100 ! specification of ureteric bud anterior/posterior symmetry +created_by: mah +creation_date: 2010-02-10T02:21:03Z + +[Term] +id: GO:0072102 +name: glomerulus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0032835 ! glomerulus development +created_by: mah +creation_date: 2010-02-10T02:32:09Z + +[Term] +id: GO:0072103 +name: glomerulus vasculature morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0048514 ! blood vessel morphogenesis +is_a: GO:0061439 ! kidney vasculature morphogenesis +relationship: part_of GO:0072012 ! glomerulus vasculature development +relationship: part_of GO:0072102 ! glomerulus morphogenesis +created_by: mah +creation_date: 2010-02-10T02:34:54Z + +[Term] +id: GO:0072104 +name: glomerular capillary formation +namespace: biological_process +def: "The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts." [GOC:mtg_kidney_jan10] +is_a: GO:0001525 ! angiogenesis +relationship: part_of GO:0072103 ! glomerulus vasculature morphogenesis +created_by: mah +creation_date: 2010-02-10T02:40:40Z + +[Term] +id: GO:0072105 +name: ureteric peristalsis +namespace: biological_process +def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10] +is_a: GO:0014849 ! ureter smooth muscle contraction +is_a: GO:0030432 ! peristalsis +created_by: mah +creation_date: 2010-02-10T03:07:54Z + +[Term] +id: GO:0072106 +name: regulation of ureteric bud formation +namespace: biological_process +def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:1905276 ! regulation of epithelial tube formation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060676 ! ureteric bud formation +relationship: regulates GO:0060676 ! ureteric bud formation +created_by: mah +creation_date: 2010-02-12T02:34:40Z + +[Term] +id: GO:0072107 +name: positive regulation of ureteric bud formation +namespace: biological_process +def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0072106 ! regulation of ureteric bud formation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905278 ! positive regulation of epithelial tube formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060676 ! ureteric bud formation +relationship: positively_regulates GO:0060676 ! ureteric bud formation +created_by: mah +creation_date: 2010-02-12T02:37:28Z + +[Term] +id: GO:0072108 +name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +relationship: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +created_by: mah +creation_date: 2010-02-12T02:45:57Z + +[Term] +id: GO:0072109 +name: glomerular mesangium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0072012 ! glomerulus vasculature development +created_by: mah +creation_date: 2010-02-22T10:35:24Z + +[Term] +id: GO:0072110 +name: glomerular mesangial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population." [GOC:mtg_kidney_jan10] +is_a: GO:0072111 ! cell proliferation involved in kidney development +relationship: part_of GO:0072109 ! glomerular mesangium development +created_by: mah +creation_date: 2010-02-22T10:45:47Z + +[Term] +id: GO:0072111 +name: cell proliferation involved in kidney development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0008283 ! cell population proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-02-22T10:48:45Z + +[Term] +id: GO:0072112 +name: glomerular visceral epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells." [GOC:mtg_kidney_jan10] +synonym: "podocyte differentiation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0061318 ! renal filtration cell differentiation +is_a: GO:0072311 ! glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-02-22T10:52:11Z + +[Term] +id: GO:0072113 +name: head kidney development +namespace: biological_process +def: "The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis." [GOC:mtg_kidney_jan10, ZFA:0000669] +is_a: GO:0048534 ! hematopoietic or lymphoid organ development +is_a: GO:0048793 ! pronephros development +created_by: mah +creation_date: 2010-02-22T11:09:38Z + +[Term] +id: GO:0072114 +name: pronephros morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] +synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0060993 ! kidney morphogenesis +relationship: part_of GO:0048793 ! pronephros development +created_by: mah +creation_date: 2010-02-22T11:12:15Z + +[Term] +id: GO:0072115 +name: head kidney morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney." [GOC:mtg_kidney_jan10, ZFA:0000669] +is_a: GO:0072114 ! pronephros morphogenesis +relationship: part_of GO:0072113 ! head kidney development +created_by: mah +creation_date: 2010-02-22T11:13:37Z + +[Term] +id: GO:0072116 +name: pronephros formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] +synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048645 ! animal organ formation +is_a: GO:0072003 ! kidney rudiment formation +relationship: part_of GO:0072114 ! pronephros morphogenesis +created_by: mah +creation_date: 2010-02-22T11:16:26Z + +[Term] +id: GO:0072117 +name: head kidney formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney." [GOC:mtg_kidney_jan10, ZFA:0000669] +is_a: GO:0072116 ! pronephros formation +relationship: part_of GO:0072115 ! head kidney morphogenesis +created_by: mah +creation_date: 2010-02-22T11:17:20Z + +[Term] +id: GO:0072118 +name: pronephros structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] +synonym: "pronephric kidney structural organization" EXACT [GOC:mtg_kidney_jan10] +synonym: "pronephros structural organisation" EXACT [GOC:mah] +is_a: GO:0048532 ! anatomical structure arrangement +relationship: part_of GO:0072114 ! pronephros morphogenesis +created_by: mah +creation_date: 2010-02-22T11:21:38Z + +[Term] +id: GO:0072119 +name: head kidney structural organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney." [GOC:mtg_kidney_jan10, ZFA:0000669] +synonym: "head kidney structural organisation" EXACT [GOC:mah] +is_a: GO:0072118 ! pronephros structural organization +relationship: part_of GO:0072115 ! head kidney morphogenesis +created_by: mah +creation_date: 2010-02-22T11:22:12Z + +[Term] +id: GO:0072120 +name: pronephros maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] +synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048799 ! animal organ maturation +relationship: part_of GO:0048793 ! pronephros development +created_by: mah +creation_date: 2010-02-22T11:25:48Z + +[Term] +id: GO:0072121 +name: head kidney maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney." [GOC:mtg_kidney_jan10, ZFA:0000669] +is_a: GO:0072120 ! pronephros maturation +relationship: part_of GO:0072113 ! head kidney development +created_by: mah +creation_date: 2010-02-22T11:28:08Z + +[Term] +id: GO:0072122 +name: extraglomerular mesangial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10] +synonym: "Goormaghtigh proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "lacis cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072111 ! cell proliferation involved in kidney development +relationship: part_of GO:0072006 ! nephron development +created_by: mah +creation_date: 2010-02-22T01:42:23Z + +[Term] +id: GO:0072123 +name: intraglomerular mesangial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis." [GOC:mtg_kidney_jan10] +is_a: GO:0072110 ! glomerular mesangial cell proliferation +created_by: mah +creation_date: 2010-02-22T01:44:29Z + +[Term] +id: GO:0072124 +name: regulation of glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0090192 ! regulation of glomerulus development +is_a: GO:1901342 ! regulation of vasculature development +is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072110 ! glomerular mesangial cell proliferation +relationship: regulates GO:0072110 ! glomerular mesangial cell proliferation +created_by: mah +creation_date: 2010-02-22T01:46:12Z + +[Term] +id: GO:0072125 +name: negative regulation of glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072124 ! regulation of glomerular mesangial cell proliferation +is_a: GO:0090194 ! negative regulation of glomerulus development +is_a: GO:1901343 ! negative regulation of vasculature development +is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072110 ! glomerular mesangial cell proliferation +relationship: negatively_regulates GO:0072110 ! glomerular mesangial cell proliferation +created_by: mah +creation_date: 2010-02-22T01:48:49Z + +[Term] +id: GO:0072126 +name: positive regulation of glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072124 ! regulation of glomerular mesangial cell proliferation +is_a: GO:0090193 ! positive regulation of glomerulus development +is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development +is_a: GO:1904018 ! positive regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072110 ! glomerular mesangial cell proliferation +relationship: positively_regulates GO:0072110 ! glomerular mesangial cell proliferation +created_by: mah +creation_date: 2010-02-22T01:49:31Z + +[Term] +id: GO:0072127 +name: renal capsule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] +is_a: GO:0061448 ! connective tissue development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-02-22T02:02:55Z + +[Term] +id: GO:0072128 +name: renal capsule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0072127 ! renal capsule development +created_by: mah +creation_date: 2010-02-22T02:06:19Z + +[Term] +id: GO:0072129 +name: renal capsule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0072128 ! renal capsule morphogenesis +created_by: mah +creation_date: 2010-02-22T02:08:14Z + +[Term] +id: GO:0072130 +name: renal capsule specification +namespace: biological_process +def: "The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:mtg_kidney_jan10] +is_a: GO:0003002 ! regionalization +is_a: GO:0061004 ! pattern specification involved in kidney development +relationship: part_of GO:0072129 ! renal capsule formation +created_by: mah +creation_date: 2010-02-22T02:12:34Z + +[Term] +id: GO:0072131 +name: kidney mesenchyme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0072132 ! mesenchyme morphogenesis +relationship: part_of GO:0072074 ! kidney mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:16:43Z + +[Term] +id: GO:0072132 +name: mesenchyme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10] +is_a: GO:0048729 ! tissue morphogenesis +relationship: part_of GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0060485 ! mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:17:15Z + +[Term] +id: GO:0072133 +name: metanephric mesenchyme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072131 ! kidney mesenchyme morphogenesis +relationship: part_of GO:0072075 ! metanephric mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:20:14Z + +[Term] +id: GO:0072134 +name: nephrogenic mesenchyme morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] +is_a: GO:0072131 ! kidney mesenchyme morphogenesis +relationship: part_of GO:0072076 ! nephrogenic mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:21:16Z + +[Term] +id: GO:0072135 +name: kidney mesenchymal cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0010463 ! mesenchymal cell proliferation +is_a: GO:0072111 ! cell proliferation involved in kidney development +relationship: part_of GO:0072074 ! kidney mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:33:10Z + +[Term] +id: GO:0072136 +name: metanephric mesenchymal cell proliferation involved in metanephros development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population." [GOC:mtg_kidney_jan10] +is_a: GO:0072135 ! kidney mesenchymal cell proliferation +is_a: GO:0072203 ! cell proliferation involved in metanephros development +relationship: part_of GO:0072075 ! metanephric mesenchyme development +created_by: mah +creation_date: 2010-02-22T02:34:56Z + +[Term] +id: GO:0072137 +name: condensed mesenchymal cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0010463 ! mesenchymal cell proliferation +created_by: mah +creation_date: 2010-02-22T02:38:54Z + +[Term] +id: GO:0072138 +name: mesenchymal cell proliferation involved in ureteric bud development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10] +synonym: "ureteric bud mesenchymal cell proliferation" BROAD [GOC:mtg_kidney_jan10] +is_a: GO:0010463 ! mesenchymal cell proliferation +is_a: GO:0061209 ! cell proliferation involved in mesonephros development +intersection_of: GO:0010463 ! mesenchymal cell proliferation +intersection_of: part_of GO:0001657 ! ureteric bud development +relationship: part_of GO:0001657 ! ureteric bud development +created_by: mah +creation_date: 2010-02-22T02:40:38Z + +[Term] +id: GO:0072139 +name: glomerular parietal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +is_a: GO:0072311 ! glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-02-24T01:33:05Z + +[Term] +id: GO:0072140 +name: DCT cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +synonym: "distal convoluted tubule cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0072069 ! DCT cell differentiation +created_by: mah +creation_date: 2010-02-24T01:36:21Z + +[Term] +id: GO:0072141 +name: renal interstitial fibroblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation +created_by: mah +creation_date: 2010-02-24T01:39:05Z + +[Term] +id: GO:0072142 +name: juxtaglomerulus cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0072052 ! juxtaglomerulus cell differentiation +created_by: mah +creation_date: 2010-02-24T01:42:53Z + +[Term] +id: GO:0072143 +name: mesangial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0072007 ! mesangial cell differentiation +created_by: mah +creation_date: 2010-02-24T01:44:28Z + +[Term] +id: GO:0072144 +name: glomerular mesangial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0002064 ! epithelial cell development +is_a: GO:0072143 ! mesangial cell development +relationship: part_of GO:0072008 ! glomerular mesangial cell differentiation +created_by: mah +creation_date: 2010-02-24T01:53:13Z + +[Term] +id: GO:0072145 +name: proximal convoluted tubule segment 1 cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "S1 cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0072062 ! proximal convoluted tubule segment 1 cell differentiation +created_by: mah +creation_date: 2010-02-24T01:54:56Z + +[Term] +id: GO:0072146 +name: DCT cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell." [GOC:mtg_kidney_jan10] +synonym: "distal convoluted tubule cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0072069 ! DCT cell differentiation +created_by: mah +creation_date: 2010-02-24T01:59:04Z + +[Term] +id: GO:0072147 +name: glomerular parietal epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes." [GOC:mtg_kidney_jan10] +synonym: "Bowman's capsule cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072148 ! epithelial cell fate commitment +is_a: GO:0072314 ! glomerular epithelial cell fate commitment +relationship: part_of GO:0072139 ! glomerular parietal epithelial cell differentiation +created_by: mah +creation_date: 2010-02-24T02:00:52Z + +[Term] +id: GO:0072148 +name: epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell." [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0030855 ! epithelial cell differentiation +created_by: mah +creation_date: 2010-02-24T02:05:03Z + +[Term] +id: GO:0072149 +name: glomerular visceral epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells." [GOC:mtg_kidney_jan10] +synonym: "podocyte cell fate commitment" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072148 ! epithelial cell fate commitment +is_a: GO:0072314 ! glomerular epithelial cell fate commitment +relationship: part_of GO:0072112 ! glomerular visceral epithelial cell differentiation +created_by: mah +creation_date: 2010-02-24T02:08:03Z + +[Term] +id: GO:0072150 +name: juxtaglomerulus cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell." [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0072052 ! juxtaglomerulus cell differentiation +created_by: mah +creation_date: 2010-02-24T02:09:49Z + +[Term] +id: GO:0072151 +name: mesangial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell." [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0072007 ! mesangial cell differentiation +created_by: mah +creation_date: 2010-02-24T02:11:13Z + +[Term] +id: GO:0072152 +name: glomerular mesangial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell." [GOC:mtg_kidney_jan10] +is_a: GO:0072151 ! mesangial cell fate commitment +relationship: part_of GO:0072008 ! glomerular mesangial cell differentiation +created_by: mah +creation_date: 2010-02-24T02:14:58Z + +[Term] +id: GO:0072153 +name: renal interstitial fibroblast fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast." [GOC:mtg_kidney_jan10] +synonym: "kidney interstitial cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation +created_by: mah +creation_date: 2010-02-24T02:16:53Z + +[Term] +id: GO:0072154 +name: proximal convoluted tubule segment 1 cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "S1 cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0072062 ! proximal convoluted tubule segment 1 cell differentiation +created_by: mah +creation_date: 2010-02-24T02:18:19Z + +[Term] +id: GO:0072155 +name: epithelial cell migration involved in nephron tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0010631 ! epithelial cell migration +is_a: GO:0035787 ! cell migration involved in kidney development +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072078 ! nephron tubule morphogenesis +relationship: part_of GO:0072078 ! nephron tubule morphogenesis +created_by: mah +creation_date: 2010-02-24T02:21:25Z + +[Term] +id: GO:0072156 +name: distal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072078 ! nephron tubule morphogenesis +relationship: part_of GO:0072017 ! distal tubule development +created_by: mah +creation_date: 2010-02-24T02:32:03Z + +[Term] +id: GO:0072157 +name: epithelial cell migration involved in distal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072156 ! distal tubule morphogenesis +relationship: part_of GO:0072156 ! distal tubule morphogenesis +created_by: mah +creation_date: 2010-02-24T02:33:33Z + +[Term] +id: GO:0072158 +name: proximal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072078 ! nephron tubule morphogenesis +relationship: part_of GO:0072014 ! proximal tubule development +created_by: mah +creation_date: 2010-02-24T02:35:36Z + +[Term] +id: GO:0072159 +name: epithelial cell migration involved in proximal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072158 ! proximal tubule morphogenesis +relationship: part_of GO:0072158 ! proximal tubule morphogenesis +created_by: mah +creation_date: 2010-02-24T02:37:08Z + +[Term] +id: GO:0072160 +name: nephron tubule epithelial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +relationship: part_of GO:0072080 ! nephron tubule development +created_by: mah +creation_date: 2010-02-24T02:40:11Z + +[Term] +id: GO:0072161 +name: mesenchymal cell differentiation involved in kidney development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0001822 ! kidney development +relationship: part_of GO:0072074 ! kidney mesenchyme development +created_by: mah +creation_date: 2010-02-26T01:31:49Z + +[Term] +id: GO:0072162 +name: metanephric mesenchymal cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0072161 ! mesenchymal cell differentiation involved in kidney development +is_a: GO:0072202 ! cell differentiation involved in metanephros development +relationship: part_of GO:0072075 ! metanephric mesenchyme development +created_by: mah +creation_date: 2010-02-26T01:35:00Z + +[Term] +id: GO:0072163 +name: mesonephric epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072073 ! kidney epithelium development +relationship: part_of GO:0001823 ! mesonephros development +created_by: mah +creation_date: 2010-02-26T01:40:43Z + +[Term] +id: GO:0072164 +name: mesonephric tubule development +namespace: biological_process +def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +is_a: GO:0072163 ! mesonephric epithelium development +created_by: mah +creation_date: 2010-02-26T01:45:58Z + +[Term] +id: GO:0072165 +name: anterior mesonephric tubule development +namespace: biological_process +def: "The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072164 ! mesonephric tubule development +created_by: mah +creation_date: 2010-02-26T01:47:26Z + +[Term] +id: GO:0072166 +name: posterior mesonephric tubule development +namespace: biological_process +def: "The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072164 ! mesonephric tubule development +created_by: mah +creation_date: 2010-02-26T01:47:50Z + +[Term] +id: GO:0072167 +name: specification of mesonephric tubule identity +namespace: biological_process +def: "The process in which the tubules of the mesonephros acquire their identity." [GOC:mtg_kidney_jan10] +is_a: GO:0061227 ! pattern specification involved in mesonephros development +is_a: GO:0072081 ! specification of nephron tubule identity +relationship: part_of GO:0072172 ! mesonephric tubule formation +created_by: mah +creation_date: 2010-02-26T01:51:03Z + +[Term] +id: GO:0072168 +name: specification of anterior mesonephric tubule identity +namespace: biological_process +def: "The process in which the tubules of the anterior mesonephros acquire their identity." [GOC:mtg_kidney_jan10] +is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development +is_a: GO:0072167 ! specification of mesonephric tubule identity +relationship: part_of GO:0072165 ! anterior mesonephric tubule development +created_by: mah +creation_date: 2010-02-26T01:52:36Z + +[Term] +id: GO:0072169 +name: specification of posterior mesonephric tubule identity +namespace: biological_process +def: "The process in which the tubules of the posterior mesonephros acquire their identity." [GOC:mtg_kidney_jan10] +is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development +is_a: GO:0072167 ! specification of mesonephric tubule identity +relationship: part_of GO:0072166 ! posterior mesonephric tubule development +created_by: mah +creation_date: 2010-02-26T01:54:06Z + +[Term] +id: GO:0072170 +name: metanephric tubule development +namespace: biological_process +def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +is_a: GO:0072207 ! metanephric epithelium development +created_by: mah +creation_date: 2010-02-26T01:58:18Z + +[Term] +id: GO:0072171 +name: mesonephric tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072078 ! nephron tubule morphogenesis +relationship: part_of GO:0072164 ! mesonephric tubule development +created_by: mah +creation_date: 2010-02-26T02:02:13Z + +[Term] +id: GO:0072172 +name: mesonephric tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072079 ! nephron tubule formation +relationship: part_of GO:0072171 ! mesonephric tubule morphogenesis +created_by: mah +creation_date: 2010-02-26T02:02:37Z + +[Term] +id: GO:0072173 +name: metanephric tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0072170 ! metanephric tubule development +created_by: mah +creation_date: 2010-02-26T02:06:42Z + +[Term] +id: GO:0072174 +name: metanephric tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0072173 ! metanephric tubule morphogenesis +created_by: mah +creation_date: 2010-02-26T02:07:41Z + +[Term] +id: GO:0072175 +name: epithelial tube formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10] +is_a: GO:0035148 ! tube formation +relationship: part_of GO:0060562 ! epithelial tube morphogenesis +created_by: mah +creation_date: 2010-02-26T02:15:40Z + +[Term] +id: GO:0072176 +name: nephric duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +is_a: GO:0072073 ! kidney epithelium development +created_by: mah +creation_date: 2010-02-26T02:27:31Z + +[Term] +id: GO:0072177 +name: mesonephric duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "Wolffian duct development" EXACT [GOC:dph] +is_a: GO:0072164 ! mesonephric tubule development +is_a: GO:0072176 ! nephric duct development +created_by: mah +creation_date: 2010-02-26T02:32:22Z + +[Term] +id: GO:0072178 +name: nephric duct morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0060562 ! epithelial tube morphogenesis +relationship: part_of GO:0072176 ! nephric duct development +created_by: mah +creation_date: 2010-02-26T02:35:29Z + +[Term] +id: GO:0072179 +name: nephric duct formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0072175 ! epithelial tube formation +relationship: part_of GO:0072178 ! nephric duct morphogenesis +created_by: mah +creation_date: 2010-02-26T02:35:55Z + +[Term] +id: GO:0072180 +name: mesonephric duct morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "Wolffian duct morphogenesis" RELATED [GOC:dph] +is_a: GO:0072171 ! mesonephric tubule morphogenesis +is_a: GO:0072178 ! nephric duct morphogenesis +relationship: part_of GO:0072177 ! mesonephric duct development +created_by: mah +creation_date: 2010-02-26T02:37:13Z + +[Term] +id: GO:0072181 +name: mesonephric duct formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10] +synonym: "Wolffian duct formation" EXACT [GOC:dph] +is_a: GO:0072172 ! mesonephric tubule formation +is_a: GO:0072179 ! nephric duct formation +is_a: GO:0072180 ! mesonephric duct morphogenesis +created_by: mah +creation_date: 2010-02-26T02:38:03Z + +[Term] +id: GO:0072182 +name: regulation of nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072160 ! nephron tubule epithelial cell differentiation +relationship: regulates GO:0072160 ! nephron tubule epithelial cell differentiation +created_by: mah +creation_date: 2010-02-26T02:45:09Z + +[Term] +id: GO:0072183 +name: negative regulation of nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation +is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation +relationship: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation +created_by: mah +creation_date: 2010-02-26T02:47:25Z + +[Term] +id: GO:0072184 +name: renal vesicle progenitor cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing." [GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +relationship: part_of GO:0072087 ! renal vesicle development +created_by: mah +creation_date: 2010-02-26T02:52:54Z + +[Term] +id: GO:0072185 +name: metanephric cap development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip." [GOC:mtg_kidney_jan10] +is_a: GO:0072075 ! metanephric mesenchyme development +created_by: mah +creation_date: 2010-03-01T01:20:22Z + +[Term] +id: GO:0072186 +name: metanephric cap morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip." [GOC:mtg_kidney_jan10] +is_a: GO:0072133 ! metanephric mesenchyme morphogenesis +relationship: part_of GO:0072185 ! metanephric cap development +created_by: mah +creation_date: 2010-03-01T01:22:51Z + +[Term] +id: GO:0072187 +name: metanephric cap formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip." [GOC:mtg_kidney_jan10] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0072186 ! metanephric cap morphogenesis +created_by: mah +creation_date: 2010-03-01T01:26:53Z + +[Term] +id: GO:0072188 +name: metanephric cap specification +namespace: biological_process +def: "The process in which the metanephric cap acquires its identity." [GOC:mtg_kidney_jan10] +is_a: GO:0072048 ! renal system pattern specification +is_a: GO:0072187 ! metanephric cap formation +is_a: GO:0072268 ! pattern specification involved in metanephros development +created_by: mah +creation_date: 2010-03-01T01:35:25Z + +[Term] +id: GO:0072189 +name: ureter development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10] +is_a: GO:0035295 ! tube development +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0072001 ! renal system development +created_by: mah +creation_date: 2010-03-01T01:44:14Z + +[Term] +id: GO:0072190 +name: ureter urothelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter." [GOC:mtg_kidney_jan10] +synonym: "ureter epithelium development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0072189 ! ureter development +created_by: mah +creation_date: 2010-03-01T01:46:31Z + +[Term] +id: GO:0072191 +name: ureter smooth muscle development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0048745 ! smooth muscle tissue development +relationship: part_of GO:0072189 ! ureter development +created_by: mah +creation_date: 2010-03-01T01:48:53Z + +[Term] +id: GO:0072192 +name: ureter epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter." [GOC:mtg_kidney_jan10] +is_a: GO:0030855 ! epithelial cell differentiation +relationship: part_of GO:0072190 ! ureter urothelium development +created_by: mah +creation_date: 2010-03-01T01:53:17Z + +[Term] +id: GO:0072193 +name: ureter smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10] +is_a: GO:0051145 ! smooth muscle cell differentiation +relationship: part_of GO:0072191 ! ureter smooth muscle development +created_by: mah +creation_date: 2010-03-01T01:55:01Z + +[Term] +id: GO:0072194 +name: kidney smooth muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0048745 ! smooth muscle tissue development +relationship: part_of GO:0001822 ! kidney development +created_by: mah +creation_date: 2010-03-01T02:05:30Z + +[Term] +id: GO:0072195 +name: kidney smooth muscle cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0051145 ! smooth muscle cell differentiation +is_a: GO:0061005 ! cell differentiation involved in kidney development +relationship: part_of GO:0072194 ! kidney smooth muscle tissue development +created_by: mah +creation_date: 2010-03-01T02:07:52Z + +[Term] +id: GO:0072196 +name: proximal/distal pattern formation involved in pronephric nephron development +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros." [GOC:mtg_kidney_jan10] +synonym: "pronephros proximal/distal pattern formation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0039017 ! pattern specification involved in pronephros development +is_a: GO:0072047 ! proximal/distal pattern formation involved in nephron development +intersection_of: GO:0009954 ! proximal/distal pattern formation +intersection_of: part_of GO:0039019 ! pronephric nephron development +relationship: part_of GO:0039019 ! pronephric nephron development +created_by: mah +creation_date: 2010-03-01T02:11:07Z + +[Term] +id: GO:0072197 +name: ureter morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10] +is_a: GO:0009887 ! animal organ morphogenesis +is_a: GO:0035239 ! tube morphogenesis +relationship: part_of GO:0072189 ! ureter development +created_by: mah +creation_date: 2010-03-01T02:24:55Z + +[Term] +id: GO:0072198 +name: mesenchymal cell proliferation involved in ureter development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10] +synonym: "ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0010463 ! mesenchymal cell proliferation +intersection_of: GO:0010463 ! mesenchymal cell proliferation +intersection_of: part_of GO:0072189 ! ureter development +relationship: part_of GO:0072189 ! ureter development +created_by: mah +creation_date: 2010-03-01T03:24:41Z + +[Term] +id: GO:0072199 +name: regulation of mesenchymal cell proliferation involved in ureter development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] +synonym: "regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +relationship: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +created_by: mah +creation_date: 2010-03-01T03:38:13Z + +[Term] +id: GO:0072200 +name: negative regulation of mesenchymal cell proliferation involved in ureter development +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] +synonym: "negative regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "negative regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development +is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +relationship: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +created_by: mah +creation_date: 2010-03-01T03:42:31Z + +[Term] +id: GO:0072201 +name: negative regulation of mesenchymal cell proliferation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010463 ! mesenchymal cell proliferation +relationship: negatively_regulates GO:0010463 ! mesenchymal cell proliferation +created_by: mah +creation_date: 2010-03-01T03:43:29Z + +[Term] +id: GO:0072202 +name: cell differentiation involved in metanephros development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10] +is_a: GO:0061005 ! cell differentiation involved in kidney development +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T10:40:14Z + +[Term] +id: GO:0072203 +name: cell proliferation involved in metanephros development +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072111 ! cell proliferation involved in kidney development +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T10:42:27Z + +[Term] +id: GO:0072204 +name: cell-cell signaling involved in metanephros development +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] +synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah] +is_a: GO:0060995 ! cell-cell signaling involved in kidney development +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T10:54:36Z + +[Term] +id: GO:0072205 +name: metanephric collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] +is_a: GO:0072044 ! collecting duct development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T11:15:37Z + +[Term] +id: GO:0072206 +name: metanephric juxtaglomerular apparatus development +namespace: biological_process +def: "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate." [GOC:mtg_kidney_jan10] +is_a: GO:0072051 ! juxtaglomerular apparatus development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T11:17:47Z + +[Term] +id: GO:0072207 +name: metanephric epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072073 ! kidney epithelium development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T11:50:37Z + +[Term] +id: GO:0072208 +name: metanephric smooth muscle tissue development +namespace: biological_process +def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072194 ! kidney smooth muscle tissue development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T11:51:59Z + +[Term] +id: GO:0072209 +name: metanephric mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0072007 ! mesangial cell differentiation +is_a: GO:0072202 ! cell differentiation involved in metanephros development +created_by: mah +creation_date: 2010-03-18T11:56:44Z + +[Term] +id: GO:0072210 +name: metanephric nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] +is_a: GO:0072006 ! nephron development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T12:52:57Z + +[Term] +id: GO:0072211 +name: metanephric pyramids development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts." [GOC:mtg_kidney_jan10] +synonym: "metanephric kidney pyramid development" EXACT [GOC:mah] +synonym: "metanephric pyramid development" EXACT [GOC:mah] +synonym: "metanephric renal medulla development" EXACT [GOC:mah] +synonym: "metanephric renal pyramid development" EXACT [GOC:mah] +is_a: GO:0072056 ! pyramid development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:04:51Z + +[Term] +id: GO:0072212 +name: regulation of transcription from RNA polymerase II promoter involved in metanephros development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0060994 ! regulation of transcription from RNA polymerase II promoter involved in kidney development +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:14:09Z + +[Term] +id: GO:0072213 +name: metanephric capsule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] +is_a: GO:0072127 ! renal capsule development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:25:19Z + +[Term] +id: GO:0072214 +name: metanephric cortex development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0060485 ! mesenchyme development +is_a: GO:0072055 ! renal cortex development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:29:49Z + +[Term] +id: GO:0072215 +name: regulation of metanephros development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001656 ! metanephros development +relationship: regulates GO:0001656 ! metanephros development + +[Term] +id: GO:0072216 +name: positive regulation of metanephros development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:0090184 ! positive regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001656 ! metanephros development +relationship: positively_regulates GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:40:12Z + +[Term] +id: GO:0072217 +name: negative regulation of metanephros development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:0090185 ! negative regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001656 ! metanephros development +relationship: negatively_regulates GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-18T01:45:48Z + +[Term] +id: GO:0072218 +name: metanephric ascending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent." [GOC:mtg_kidney_jan10] +is_a: GO:0072021 ! ascending thin limb development +is_a: GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072236 ! metanephric loop of Henle development +created_by: mah +creation_date: 2010-03-18T03:34:42Z + +[Term] +id: GO:0072219 +name: metanephric cortical collecting duct development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] +is_a: GO:0072059 ! cortical collecting duct development +created_by: mah +creation_date: 2010-03-18T03:34:52Z + +[Term] +id: GO:0072220 +name: metanephric descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle." [GOC:mtg_kidney_jan10] +is_a: GO:0072022 ! descending thin limb development +relationship: part_of GO:0072236 ! metanephric loop of Henle development +created_by: mah +creation_date: 2010-03-18T03:35:05Z + +[Term] +id: GO:0072221 +name: metanephric distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter." [GOC:mtg_kidney_jan10] +is_a: GO:0072025 ! distal convoluted tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072235 ! metanephric distal tubule development +created_by: mah +creation_date: 2010-03-18T03:35:27Z + +[Term] +id: GO:0072222 +name: metanephric early distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive." [GOC:mtg_kidney_jan10] +is_a: GO:0072067 ! early distal convoluted tubule development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072221 ! metanephric distal convoluted tubule development +created_by: mah +creation_date: 2010-03-18T03:35:46Z + +[Term] +id: GO:0072223 +name: metanephric glomerular mesangium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072109 ! glomerular mesangium development +relationship: part_of GO:0072239 ! metanephric glomerulus vasculature development +created_by: mah +creation_date: 2010-03-18T03:35:56Z + +[Term] +id: GO:0072224 +name: metanephric glomerulus development +namespace: biological_process +def: "The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros." [GOC:mah] +synonym: "metanephric glomerular development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0032835 ! glomerulus development +relationship: part_of GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-18T03:36:20Z + +[Term] +id: GO:0072225 +name: metanephric late distal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive." [GOC:mtg_kidney_jan10] +is_a: GO:0072068 ! late distal convoluted tubule development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072221 ! metanephric distal convoluted tubule development +created_by: mah +creation_date: 2010-03-18T03:37:04Z + +[Term] +id: GO:0072226 +name: metanephric long descending thin limb bend development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072065 ! long descending thin limb bend development +relationship: part_of GO:0072220 ! metanephric descending thin limb development +relationship: part_of GO:0072269 ! metanephric long descending thin limb development +created_by: mah +creation_date: 2010-03-18T03:37:16Z + +[Term] +id: GO:0072227 +name: metanephric macula densa development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072024 ! macula densa development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072206 ! metanephric juxtaglomerular apparatus development +created_by: mah +creation_date: 2010-03-18T03:37:26Z + +[Term] +id: GO:0072228 +name: metanephric prebend segment development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability." [GOC:mtg_kidney_jan10] +is_a: GO:0072066 ! prebend segment development +relationship: part_of GO:0072220 ! metanephric descending thin limb development +created_by: mah +creation_date: 2010-03-18T03:37:46Z + +[Term] +id: GO:0072229 +name: metanephric proximal convoluted tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072019 ! proximal convoluted tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072237 ! metanephric proximal tubule development +created_by: mah +creation_date: 2010-03-18T03:37:56Z + +[Term] +id: GO:0072230 +name: metanephric proximal straight tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule." [GOC:mtg_kidney_jan10] +synonym: "metanephric S3 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072020 ! proximal straight tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072237 ! metanephric proximal tubule development +created_by: mah +creation_date: 2010-03-18T03:38:53Z + +[Term] +id: GO:0072231 +name: metanephric proximal convoluted tubule segment 1 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "metanephric S1 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072031 ! proximal convoluted tubule segment 1 development +relationship: part_of GO:0072229 ! metanephric proximal convoluted tubule development +created_by: mah +creation_date: 2010-03-18T03:39:10Z + +[Term] +id: GO:0072232 +name: metanephric proximal convoluted tubule segment 2 development +namespace: biological_process +def: "The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "metanephric S2 development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072032 ! proximal convoluted tubule segment 2 development +relationship: part_of GO:0072229 ! metanephric proximal convoluted tubule development +created_by: mah +creation_date: 2010-03-18T03:39:28Z + +[Term] +id: GO:0072233 +name: metanephric thick ascending limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule." [GOC:mtg_kidney_jan10] +synonym: "metanephric TAL development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072023 ! thick ascending limb development +is_a: GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072235 ! metanephric distal tubule development +created_by: mah +creation_date: 2010-03-18T03:39:36Z + +[Term] +id: GO:0072234 +name: metanephric nephron tubule development +namespace: biological_process +def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072080 ! nephron tubule development +is_a: GO:0072170 ! metanephric tubule development +is_a: GO:0072243 ! metanephric nephron epithelium development +created_by: mah +creation_date: 2010-03-18T03:41:23Z + +[Term] +id: GO:0072235 +name: metanephric distal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072017 ! distal tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +created_by: mah +creation_date: 2010-03-18T03:45:37Z + +[Term] +id: GO:0072236 +name: metanephric loop of Henle development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric intermediate tubule development" EXACT [] +is_a: GO:0072070 ! loop of Henle development +is_a: GO:0072234 ! metanephric nephron tubule development +created_by: mah +creation_date: 2010-03-18T03:46:18Z + +[Term] +id: GO:0072237 +name: metanephric proximal tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072014 ! proximal tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +created_by: mah +creation_date: 2010-03-18T03:46:54Z + +[Term] +id: GO:0072238 +name: metanephric long nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric juxtamedullary nephron development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072029 ! long nephron development +is_a: GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-18T03:48:23Z + +[Term] +id: GO:0072239 +name: metanephric glomerulus vasculature development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus." [GOC:mtg_kidney_jan10] +synonym: "glomerulus capillary development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072012 ! glomerulus vasculature development +relationship: part_of GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-03-18T03:50:29Z + +[Term] +id: GO:0072240 +name: metanephric DCT cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "metanephric distal convoluted tubule cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072069 ! DCT cell differentiation +is_a: GO:0072202 ! cell differentiation involved in metanephros development +relationship: part_of GO:0072221 ! metanephric distal convoluted tubule development +created_by: mah +creation_date: 2010-03-19T03:24:25Z + +[Term] +id: GO:0072241 +name: metanephric DCT cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +synonym: "metanephric distal convoluted tubule cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072140 ! DCT cell development +relationship: part_of GO:0072240 ! metanephric DCT cell differentiation +created_by: mah +creation_date: 2010-03-19T03:26:44Z + +[Term] +id: GO:0072242 +name: metanephric DCT cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell." [GOC:mtg_kidney_jan10] +synonym: "metanephric distal convoluted tubule cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072146 ! DCT cell fate commitment +relationship: part_of GO:0072240 ! metanephric DCT cell differentiation +created_by: mah +creation_date: 2010-03-19T03:27:00Z + +[Term] +id: GO:0072243 +name: metanephric nephron epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072009 ! nephron epithelium development +is_a: GO:0072207 ! metanephric epithelium development +created_by: mah +creation_date: 2010-03-19T03:29:49Z + +[Term] +id: GO:0072244 +name: metanephric glomerular epithelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072010 ! glomerular epithelium development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-03-19T03:38:47Z + +[Term] +id: GO:0072245 +name: metanephric glomerular parietal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +is_a: GO:0072139 ! glomerular parietal epithelial cell differentiation +is_a: GO:0072312 ! metanephric glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:41:26Z + +[Term] +id: GO:0072246 +name: metanephric glomerular parietal epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport." [GOC:mtg_kidney_jan10] +synonym: "metanephric Bowman's capsule development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072016 ! glomerular parietal epithelial cell development +is_a: GO:0072313 ! metanephric glomerular epithelial cell development +relationship: part_of GO:0072245 ! metanephric glomerular parietal epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:42:13Z + +[Term] +id: GO:0072247 +name: metanephric glomerular parietal epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes." [GOC:mtg_kidney_jan10] +synonym: "metanephric Bowman's capsule cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072147 ! glomerular parietal epithelial cell fate commitment +is_a: GO:0072315 ! metanephric glomerular epithelial cell fate commitment +relationship: part_of GO:0072245 ! metanephric glomerular parietal epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:42:27Z + +[Term] +id: GO:0072248 +name: metanephric glomerular visceral epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric podocyte differentiation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072112 ! glomerular visceral epithelial cell differentiation +is_a: GO:0072312 ! metanephric glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:44:57Z + +[Term] +id: GO:0072249 +name: metanephric glomerular visceral epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric podocyte development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072015 ! glomerular visceral epithelial cell development +is_a: GO:0072313 ! metanephric glomerular epithelial cell development +relationship: part_of GO:0072248 ! metanephric glomerular visceral epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:46:26Z + +[Term] +id: GO:0072250 +name: metanephric glomerular visceral epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric podocyte cell fate commitment" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072149 ! glomerular visceral epithelial cell fate commitment +is_a: GO:0072315 ! metanephric glomerular epithelial cell fate commitment +relationship: part_of GO:0072248 ! metanephric glomerular visceral epithelial cell differentiation +created_by: mah +creation_date: 2010-03-19T03:46:41Z + +[Term] +id: GO:0072251 +name: metanephric juxtaglomerulus cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0072052 ! juxtaglomerulus cell differentiation +is_a: GO:0072202 ! cell differentiation involved in metanephros development +relationship: part_of GO:0072206 ! metanephric juxtaglomerular apparatus development +created_by: mah +creation_date: 2010-03-19T03:54:35Z + +[Term] +id: GO:0072252 +name: metanephric juxtaglomerulus cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072142 ! juxtaglomerulus cell development +relationship: part_of GO:0072251 ! metanephric juxtaglomerulus cell differentiation +created_by: mah +creation_date: 2010-03-19T03:55:31Z + +[Term] +id: GO:0072253 +name: metanephric juxtaglomerulus cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell." [GOC:mtg_kidney_jan10] +is_a: GO:0072150 ! juxtaglomerulus cell fate commitment +relationship: part_of GO:0072251 ! metanephric juxtaglomerulus cell differentiation +created_by: mah +creation_date: 2010-03-19T03:55:47Z + +[Term] +id: GO:0072254 +name: metanephric glomerular mesangial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0072008 ! glomerular mesangial cell differentiation +is_a: GO:0072209 ! metanephric mesangial cell differentiation +relationship: part_of GO:0072223 ! metanephric glomerular mesangium development +created_by: mah +creation_date: 2010-03-19T04:04:02Z + +[Term] +id: GO:0072255 +name: metanephric glomerular mesangial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +is_a: GO:0072144 ! glomerular mesangial cell development +relationship: part_of GO:0072254 ! metanephric glomerular mesangial cell differentiation +created_by: mah +creation_date: 2010-03-19T04:06:58Z + +[Term] +id: GO:0072256 +name: metanephric glomerular mesangial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell." [GOC:mtg_kidney_jan10] +is_a: GO:0072152 ! glomerular mesangial cell fate commitment +relationship: part_of GO:0072254 ! metanephric glomerular mesangial cell differentiation +created_by: mah +creation_date: 2010-03-19T04:07:10Z + +[Term] +id: GO:0072257 +name: metanephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +is_a: GO:0072160 ! nephron tubule epithelial cell differentiation +is_a: GO:0072202 ! cell differentiation involved in metanephros development +relationship: part_of GO:0072234 ! metanephric nephron tubule development +created_by: mah +creation_date: 2010-03-19T04:11:02Z + +[Term] +id: GO:0072258 +name: metanephric interstitial fibroblast differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] +synonym: "metanephros interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072071 ! kidney interstitial fibroblast differentiation +is_a: GO:0072202 ! cell differentiation involved in metanephros development +created_by: mah +creation_date: 2010-03-19T04:17:32Z + +[Term] +id: GO:0072259 +name: metanephric interstitial fibroblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] +synonym: "metanephros interstitial cell development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072141 ! renal interstitial fibroblast development +relationship: part_of GO:0072258 ! metanephric interstitial fibroblast differentiation +created_by: mah +creation_date: 2010-03-19T04:18:00Z + +[Term] +id: GO:0072260 +name: metanephric interstitial fibroblast fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast." [GOC:mtg_kidney_jan10] +synonym: "metanephros interstitial cell fate commitment" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072153 ! renal interstitial fibroblast fate commitment +relationship: part_of GO:0072258 ! metanephric interstitial fibroblast differentiation +created_by: mah +creation_date: 2010-03-19T04:18:10Z + +[Term] +id: GO:0072261 +name: metanephric extraglomerular mesangial cell proliferation involved in metanephros development +namespace: biological_process +def: "The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa." [GOC:mtg_kidney_jan10] +synonym: "metanephric Goormaghtigh proliferation" RELATED [GOC:mtg_kidney_jan10] +synonym: "metanephric lacis cell proliferation" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0072122 ! extraglomerular mesangial cell proliferation +is_a: GO:0072203 ! cell proliferation involved in metanephros development +relationship: part_of GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-30T02:14:17Z + +[Term] +id: GO:0072262 +name: metanephric glomerular mesangial cell proliferation involved in metanephros development +namespace: biological_process +def: "The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population." [GOC:mtg_kidney_jan10] +is_a: GO:0072110 ! glomerular mesangial cell proliferation +is_a: GO:0072203 ! cell proliferation involved in metanephros development +relationship: part_of GO:0072223 ! metanephric glomerular mesangium development +created_by: mah +creation_date: 2010-03-30T02:27:27Z + +[Term] +id: GO:0072263 +name: metanephric intraglomerular mesangial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis." [GOC:mtg_kidney_jan10] +is_a: GO:0072123 ! intraglomerular mesangial cell proliferation +is_a: GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +created_by: mah +creation_date: 2010-03-30T02:27:53Z + +[Term] +id: GO:0072264 +name: metanephric glomerular endothelium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072011 ! glomerular endothelium development +is_a: GO:0072244 ! metanephric glomerular epithelium development +relationship: part_of GO:0072239 ! metanephric glomerulus vasculature development +created_by: mah +creation_date: 2010-03-30T02:42:26Z + +[Term] +id: GO:0072265 +name: metanephric capsule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] +is_a: GO:0072128 ! renal capsule morphogenesis +relationship: part_of GO:0072213 ! metanephric capsule development +created_by: mah +creation_date: 2010-03-30T02:54:49Z + +[Term] +id: GO:0072266 +name: metanephric capsule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] +is_a: GO:0072129 ! renal capsule formation +relationship: part_of GO:0072265 ! metanephric capsule morphogenesis +created_by: mah +creation_date: 2010-03-30T02:56:35Z + +[Term] +id: GO:0072267 +name: metanephric capsule specification +namespace: biological_process +def: "The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:mtg_kidney_jan10] +is_a: GO:0072130 ! renal capsule specification +is_a: GO:0072268 ! pattern specification involved in metanephros development +relationship: part_of GO:0072266 ! metanephric capsule formation +created_by: mah +creation_date: 2010-03-30T02:57:36Z + +[Term] +id: GO:0072268 +name: pattern specification involved in metanephros development +namespace: biological_process +def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] +synonym: "metanephros pattern formation" RELATED [GOC:mtg_kidney_jan10] +synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10] +synonym: "pattern formation involved in metanephros development" RELATED [GOC:mtg_kidney_jan10] +is_a: GO:0061004 ! pattern specification involved in kidney development +intersection_of: GO:0007389 ! pattern specification process +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: mah +creation_date: 2010-03-30T03:06:30Z + +[Term] +id: GO:0072269 +name: metanephric long descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla." [GOC:mtg_kidney_jan10] +is_a: GO:0072064 ! long descending thin limb development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072238 ! metanephric long nephron development +created_by: mah +creation_date: 2010-03-30T03:12:05Z + +[Term] +id: GO:0072270 +name: metanephric short nephron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb." [GOC:mtg_kidney_jan10] +is_a: GO:0072030 ! short nephron development +is_a: GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-30T03:15:18Z + +[Term] +id: GO:0072271 +name: metanephric short descending thin limb development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072063 ! short descending thin limb development +is_a: GO:0072243 ! metanephric nephron epithelium development +relationship: part_of GO:0072270 ! metanephric short nephron development +created_by: mah +creation_date: 2010-03-30T03:16:25Z + +[Term] +id: GO:0072272 +name: proximal/distal pattern formation involved in metanephric nephron development +namespace: biological_process +def: "The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)." [GOC:mtg_kidney_jan10] +synonym: "proximal-distal pattern formation involved in metanephric nephron development" EXACT [GOC:mtg_kidney_jan10] +synonym: "proximal/distal metanephric nephron patterning" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072047 ! proximal/distal pattern formation involved in nephron development +is_a: GO:0072268 ! pattern specification involved in metanephros development +intersection_of: GO:0009954 ! proximal/distal pattern formation +intersection_of: part_of GO:0072210 ! metanephric nephron development +relationship: part_of GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-30T03:25:37Z + +[Term] +id: GO:0072273 +name: metanephric nephron morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0003338 ! metanephros morphogenesis +relationship: part_of GO:0072210 ! metanephric nephron development +created_by: mah +creation_date: 2010-03-30T03:33:19Z + +[Term] +id: GO:0072274 +name: metanephric glomerular basement membrane development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration." [GOC:mtg_kidney_jan10] +is_a: GO:0032836 ! glomerular basement membrane development +relationship: part_of GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-04-01T02:43:51Z + +[Term] +id: GO:0072275 +name: metanephric glomerulus morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072102 ! glomerulus morphogenesis +relationship: part_of GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-04-01T02:46:58Z + +[Term] +id: GO:0072276 +name: metanephric glomerulus vasculature morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus." [GOC:mtg_kidney_jan10] +is_a: GO:0072103 ! glomerulus vasculature morphogenesis +relationship: part_of GO:0072239 ! metanephric glomerulus vasculature development +relationship: part_of GO:0072275 ! metanephric glomerulus morphogenesis +created_by: mah +creation_date: 2010-04-01T02:47:32Z + +[Term] +id: GO:0072277 +name: metanephric glomerular capillary formation +namespace: biological_process +def: "The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts." [GOC:mtg_kidney_jan10] +is_a: GO:0072104 ! glomerular capillary formation +relationship: part_of GO:0072276 ! metanephric glomerulus vasculature morphogenesis +created_by: mah +creation_date: 2010-04-01T02:47:56Z + +[Term] +id: GO:0072278 +name: metanephric comma-shaped body morphogenesis +namespace: biological_process +def: "The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072049 ! comma-shaped body morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:14:42Z + +[Term] +id: GO:0072279 +name: convergent extension involved in metanephric nephron morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072045 ! convergent extension involved in nephron morphogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:16:11Z + +[Term] +id: GO:0072280 +name: establishment of planar polarity involved in metanephric nephron morphogenesis +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "establishment of planar cell polarity involved in metanephric nephron morphogenesis" NARROW [GOC:mtg_kidney_jan10] +is_a: GO:0072046 ! establishment of planar polarity involved in nephron morphogenesis +intersection_of: GO:0001736 ! establishment of planar polarity +intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:17:18Z + +[Term] +id: GO:0072281 +name: mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0061208 ! cell differentiation involved in mesonephros development +is_a: GO:0072037 ! mesenchymal stem cell differentiation involved in nephron morphogenesis +is_a: GO:0072202 ! cell differentiation involved in metanephros development +intersection_of: GO:0072497 ! mesenchymal stem cell differentiation +intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:22:06Z + +[Term] +id: GO:0072282 +name: metanephric nephron tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072078 ! nephron tubule morphogenesis +is_a: GO:0072173 ! metanephric tubule morphogenesis +relationship: part_of GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:25:11Z + +[Term] +id: GO:0072283 +name: metanephric renal vesicle morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072077 ! renal vesicle morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:28:00Z + +[Term] +id: GO:0072284 +name: metanephric S-shaped body morphogenesis +namespace: biological_process +def: "The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072050 ! S-shaped body morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-01T03:41:36Z + +[Term] +id: GO:0072285 +name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation +namespace: biological_process +def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] +is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis +is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation +intersection_of: GO:0060231 ! mesenchymal to epithelial transition +intersection_of: part_of GO:0072093 ! metanephric renal vesicle formation +relationship: part_of GO:0072093 ! metanephric renal vesicle formation +created_by: mah +creation_date: 2010-04-01T03:43:31Z + +[Term] +id: GO:0072286 +name: metanephric connecting tubule development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros." [GOC:mtg_kidney_jan10] +synonym: "metanephric connecting duct development" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072027 ! connecting tubule development +is_a: GO:0072234 ! metanephric nephron tubule development +created_by: mah +creation_date: 2010-04-09T03:30:09Z + +[Term] +id: GO:0072287 +name: metanephric distal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule." [GOC:mtg_kidney_jan10] +is_a: GO:0072156 ! distal tubule morphogenesis +is_a: GO:0072282 ! metanephric nephron tubule morphogenesis +relationship: part_of GO:0072235 ! metanephric distal tubule development +created_by: mah +creation_date: 2010-04-09T03:41:47Z + +[Term] +id: GO:0072288 +name: metanephric proximal tubule morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology." [GOC:mtg_kidney_jan10] +is_a: GO:0072158 ! proximal tubule morphogenesis +is_a: GO:0072282 ! metanephric nephron tubule morphogenesis +relationship: part_of GO:0072237 ! metanephric proximal tubule development +created_by: mah +creation_date: 2010-04-09T03:42:03Z + +[Term] +id: GO:0072289 +name: metanephric nephron tubule formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072079 ! nephron tubule formation +is_a: GO:0072174 ! metanephric tubule formation +relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T03:47:44Z + +[Term] +id: GO:0072290 +name: epithelial cell migration involved in metanephric nephron tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0035788 ! cell migration involved in metanephros development +is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072282 ! metanephric nephron tubule morphogenesis +relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T03:52:29Z + +[Term] +id: GO:0072291 +name: epithelial cell migration involved in metanephric distal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0072157 ! epithelial cell migration involved in distal tubule morphogenesis +is_a: GO:0072290 ! epithelial cell migration involved in metanephric nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072287 ! metanephric distal tubule morphogenesis +relationship: part_of GO:0072287 ! metanephric distal tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T03:53:37Z + +[Term] +id: GO:0072292 +name: epithelial cell migration involved in metanephric proximal tubule morphogenesis +namespace: biological_process +def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis." [GOC:mtg_kidney_jan10] +is_a: GO:0072159 ! epithelial cell migration involved in proximal tubule morphogenesis +is_a: GO:0072290 ! epithelial cell migration involved in metanephric nephron tubule morphogenesis +intersection_of: GO:0010631 ! epithelial cell migration +intersection_of: part_of GO:0072288 ! metanephric proximal tubule morphogenesis +relationship: part_of GO:0072288 ! metanephric proximal tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T03:54:28Z + +[Term] +id: GO:0072293 +name: specification of metanephric nephron tubule identity +namespace: biological_process +def: "The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072081 ! specification of nephron tubule identity +is_a: GO:0072268 ! pattern specification involved in metanephros development +relationship: part_of GO:0072272 ! proximal/distal pattern formation involved in metanephric nephron development +relationship: part_of GO:0072289 ! metanephric nephron tubule formation +created_by: mah +creation_date: 2010-04-09T03:58:10Z + +[Term] +id: GO:0072294 +name: specification of metanephric connecting tubule identity +namespace: biological_process +def: "The process in which the connecting tubule of the metanephric nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072085 ! specification of connecting tubule identity +is_a: GO:0072293 ! specification of metanephric nephron tubule identity +relationship: part_of GO:0072286 ! metanephric connecting tubule development +created_by: mah +creation_date: 2010-04-09T04:00:31Z + +[Term] +id: GO:0072295 +name: specification of metanephric distal tubule identity +namespace: biological_process +def: "The process in which the distal tubule of the metanephric nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072084 ! specification of distal tubule identity +is_a: GO:0072293 ! specification of metanephric nephron tubule identity +relationship: part_of GO:0072287 ! metanephric distal tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T04:01:42Z + +[Term] +id: GO:0072296 +name: specification of metanephric loop of Henle identity +namespace: biological_process +def: "The process in which the loop of Henle of the metanephric nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +synonym: "specification of metanephric intermediate tubule identity" EXACT [GOC:mtg_kidney_jan10] +is_a: GO:0072086 ! specification of loop of Henle identity +is_a: GO:0072293 ! specification of metanephric nephron tubule identity +relationship: part_of GO:0072236 ! metanephric loop of Henle development +created_by: mah +creation_date: 2010-04-09T04:08:05Z + +[Term] +id: GO:0072297 +name: specification of metanephric proximal tubule identity +namespace: biological_process +def: "The process in which the proximal tubule of the metanephric nephron acquires its identity." [GOC:bf, GOC:mtg_kidney_jan10] +is_a: GO:0072082 ! specification of proximal tubule identity +is_a: GO:0072293 ! specification of metanephric nephron tubule identity +relationship: part_of GO:0072288 ! metanephric proximal tubule morphogenesis +created_by: mah +creation_date: 2010-04-09T04:08:20Z + +[Term] +id: GO:0072298 +name: regulation of metanephric glomerulus development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0001656 ! metanephros development +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:0090192 ! regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072224 ! metanephric glomerulus development +relationship: regulates GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-04-09T05:03:14Z + +[Term] +id: GO:0072299 +name: negative regulation of metanephric glomerulus development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0072298 ! regulation of metanephric glomerulus development +is_a: GO:0090194 ! negative regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072224 ! metanephric glomerulus development +relationship: negatively_regulates GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072300 +name: positive regulation of metanephric glomerulus development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros." [GOC:mtg_kidney_jan10] +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:0072298 ! regulation of metanephric glomerulus development +is_a: GO:0090193 ! positive regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072224 ! metanephric glomerulus development +relationship: positively_regulates GO:0072224 ! metanephric glomerulus development +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072301 +name: regulation of metanephric glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072124 ! regulation of glomerular mesangial cell proliferation +is_a: GO:0072298 ! regulation of metanephric glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +relationship: regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072302 +name: negative regulation of metanephric glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072125 ! negative regulation of glomerular mesangial cell proliferation +is_a: GO:0072299 ! negative regulation of metanephric glomerulus development +is_a: GO:0072301 ! regulation of metanephric glomerular mesangial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +relationship: negatively_regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072303 +name: positive regulation of glomerular metanephric mesangial cell proliferation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072126 ! positive regulation of glomerular mesangial cell proliferation +is_a: GO:0072300 ! positive regulation of metanephric glomerulus development +is_a: GO:0072301 ! regulation of metanephric glomerular mesangial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +relationship: positively_regulates GO:0072262 ! metanephric glomerular mesangial cell proliferation involved in metanephros development +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072304 +name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +namespace: biological_process +def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] +synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] +is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +relationship: regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis +relationship: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072305 +name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +namespace: biological_process +def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] +synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] +is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +relationship: negatively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis +relationship: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072306 +name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +namespace: biological_process +def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] +synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] +synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] +is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis +is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +relationship: positively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis +relationship: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072307 +name: regulation of metanephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation +is_a: GO:0072215 ! regulation of metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation +relationship: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072308 +name: negative regulation of metanephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation +relationship: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072309 +name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis +namespace: biological_process +def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: mah +creation_date: 2010-04-09T05:03:41Z + +[Term] +id: GO:0072310 +name: glomerular epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0072311 ! glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-04-09T06:47:31Z + +[Term] +id: GO:0072311 +name: glomerular epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development +relationship: part_of GO:0072010 ! glomerular epithelium development +created_by: mah +creation_date: 2010-04-09T06:49:21Z + +[Term] +id: GO:0072312 +name: metanephric glomerular epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072202 ! cell differentiation involved in metanephros development +is_a: GO:0072311 ! glomerular epithelial cell differentiation +relationship: part_of GO:0072244 ! metanephric glomerular epithelium development +created_by: mah +creation_date: 2010-04-09T06:54:15Z + +[Term] +id: GO:0072313 +name: metanephric glomerular epithelial cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072310 ! glomerular epithelial cell development +relationship: part_of GO:0072312 ! metanephric glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-04-09T06:57:26Z + +[Term] +id: GO:0072314 +name: glomerular epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0002064 ! epithelial cell development +relationship: part_of GO:0072311 ! glomerular epithelial cell differentiation +created_by: mah +creation_date: 2010-04-09T07:02:25Z + +[Term] +id: GO:0072315 +name: metanephric glomerular epithelial cell fate commitment +namespace: biological_process +def: "The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells." [GOC:mtg_kidney_jan10] +is_a: GO:0072314 ! glomerular epithelial cell fate commitment +created_by: mah +creation_date: 2010-04-09T07:03:50Z + +[Term] +id: GO:0072316 +name: alpha-glucan catabolic process involved in ascospore release from ascus +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus." [GOC:mah] +synonym: "alpha-glucan breakdown involved in ascospore release from ascus" EXACT [GOC:mah] +synonym: "alpha-glucan catabolism involved in ascospore release from ascus" EXACT [GOC:mah] +synonym: "alpha-glucan degradation involved in ascospore release from ascus" EXACT [GOC:mah] +is_a: GO:0030980 ! alpha-glucan catabolic process +is_a: GO:0072000 ! extracellular polysaccharide catabolic process involved in ascospore release from ascus +intersection_of: GO:0030980 ! alpha-glucan catabolic process +intersection_of: part_of GO:0071998 ! ascospore release from ascus +created_by: mah +creation_date: 2010-10-25T05:43:52Z + +[Term] +id: GO:0072317 +name: obsolete glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus." [GOC:jl] +comment: This term was obsoleted because it should be captured as a GO-CAM model. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15204 xsd:anyURI +is_obsolete: true +created_by: mah +creation_date: 2010-10-25T05:46:13Z + +[Term] +id: GO:0072318 +name: clathrin coat disassembly +namespace: biological_process +def: "The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system." [PMID:11084334, PMID:11146663, PMID:8524399] +synonym: "clathrin-coat disassembly" EXACT [GOC:rb] +synonym: "clathrin-coat uncoating" EXACT [GOC:rb] +synonym: "clathrin-coated vesicle uncoating" EXACT [GOC:mah] +is_a: GO:0072319 ! vesicle uncoating +created_by: mah +creation_date: 2010-10-26T12:03:37Z + +[Term] +id: GO:0072319 +name: vesicle uncoating +namespace: biological_process +def: "A protein depolymerization process that results in the disassembly of vesicle coat proteins." [GOC:mah] +synonym: "vesicle coat disassembly" EXACT [GOC:mah] +is_a: GO:0051261 ! protein depolymerization +relationship: part_of GO:0016192 ! vesicle-mediated transport +created_by: mah +creation_date: 2010-10-26T12:09:21Z + +[Term] +id: GO:0072320 +name: volume-sensitive chloride channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell." [GOC:mah] +synonym: "swell-activated chloride channel" RELATED [GOC:sart, PMID:23056495] +is_a: GO:0005225 ! volume-sensitive anion channel activity +is_a: GO:0005254 ! chloride channel activity +created_by: mah +creation_date: 2010-10-26T12:53:38Z + +[Term] +id: GO:0072321 +name: chaperone-mediated protein transport +namespace: biological_process +def: "The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins." [GOC:mah, PMID:20378773] +is_a: GO:0015031 ! protein transport +created_by: mah +creation_date: 2010-10-28T04:23:20Z + +[Term] +id: GO:0072322 +name: protein transport across periplasmic space +namespace: biological_process +def: "The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall." [GOC:mah] +is_a: GO:0015031 ! protein transport +created_by: mah +creation_date: 2010-10-28T04:24:59Z + +[Term] +id: GO:0072323 +name: chaperone-mediated protein transport across periplasmic space +namespace: biological_process +def: "The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane, mediated by chaperone molecules that bind to the transported proteins. This process has been observed in Gram-negative bacteria." [GOC:mah, PMID:20378773] +is_a: GO:0072321 ! chaperone-mediated protein transport +is_a: GO:0072322 ! protein transport across periplasmic space +created_by: mah +creation_date: 2010-10-28T04:26:53Z + +[Term] +id: GO:0072324 +name: ascus epiplasm +namespace: cellular_component +def: "Ascus cytoplasm that is not packaged into ascospores." [DOI:10.1016/S0953-7562(96)80057-8, GOC:mcc] +comment: Note that this term is an is_a child of 'cell part' because the epiplasm is extracellular to the spore (each of which is a cell) but within the ascus structure, and originated from cytoplasm. +is_a: GO:0110165 ! cellular anatomical entity +property_value: RO:0002161 NCBITaxon:5878 +created_by: mah +creation_date: 2010-10-28T04:37:46Z + +[Term] +id: GO:0072325 +name: vulval cell fate commitment +namespace: biological_process +def: "The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes." [GOC:kmv, GOC:mah, ISBN:087969307X, PMID:11236714] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0040025 ! vulval development +created_by: mah +creation_date: 2010-11-01T02:02:16Z + +[Term] +id: GO:0072326 +name: vulval cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes." [GOC:kmv, GOC:mah, ISBN:087969307X, PMID:11236714] +is_a: GO:0001709 ! cell fate determination +relationship: part_of GO:0072325 ! vulval cell fate commitment +created_by: mah +creation_date: 2010-11-01T02:04:46Z + +[Term] +id: GO:0072327 +name: vulval cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes." [GOC:kmv, GOC:mah, ISBN:087969307X, PMID:11236714] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0072325 ! vulval cell fate commitment +created_by: mah +creation_date: 2010-11-01T02:14:06Z + +[Term] +id: GO:0072328 +name: alkene binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n." [GOC:mah] +is_a: GO:0005488 ! binding +created_by: mah +creation_date: 2010-11-02T12:39:40Z + +[Term] +id: GO:0072329 +name: monocarboxylic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +created_by: mah +creation_date: 2010-11-02T04:41:55Z + +[Term] +id: GO:0072330 +name: monocarboxylic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] +synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah] +synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah] +synonym: "monocarboxylic acid formation" EXACT [GOC:mah] +synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +created_by: mah +creation_date: 2010-11-02T04:51:32Z + +[Term] +id: GO:0072331 +name: signal transduction by p53 class mediator +namespace: biological_process +def: "An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein." [GOC:mah] +is_a: GO:0035556 ! intracellular signal transduction +created_by: mah +creation_date: 2010-11-03T01:32:59Z + +[Term] +id: GO:0072332 +name: intrinsic apoptotic signaling pathway by p53 class mediator +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered." [GOC:mah, GOC:mtg_apoptosis] +synonym: "intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [] +synonym: "signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [] +is_a: GO:0072331 ! signal transduction by p53 class mediator +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway +created_by: mah +creation_date: 2010-11-03T01:47:56Z + +[Term] +id: GO:0072333 +name: obsolete anoikis by p53 class mediator +namespace: biological_process +def: "OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, that results in the induction of anoikis." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +comment: This term was made obsolete because it is misleading, since anoikis occurs following detachment of cells from each other and/or from the culture surface; it is not p53 that induces such separation. +synonym: "anoikis by p53 class mediator" EXACT [] +synonym: "anoikis by signal transduction by p53 class mediator" EXACT [] +synonym: "signal transduction by p53 class mediator resulting in induction of anoikis" RELATED [] +is_obsolete: true +created_by: mah +creation_date: 2010-11-03T01:52:56Z + +[Term] +id: GO:0072334 +name: UDP-galactose transmembrane transport +namespace: biological_process +alt_id: GO:0015785 +def: "The process in which UDP-galactose is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "UDP-galactose membrane transport" EXACT [] +synonym: "UDP-galactose transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +created_by: mah +creation_date: 2010-11-03T02:03:36Z + +[Term] +id: GO:0072335 +name: regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:dgh] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation" EXACT [] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation" EXACT [GOC:signaling] +synonym: "regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation" EXACT [GOC:mah] +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +is_a: GO:1905292 ! regulation of neural crest cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +relationship: regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +created_by: mah +creation_date: 2010-11-03T03:12:38Z + +[Term] +id: GO:0072336 +name: negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:dgh] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation" EXACT [] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation" RELATED [] +synonym: "negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation" EXACT [GOC:mah] +is_a: GO:0072335 ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:1905293 ! negative regulation of neural crest cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +relationship: negatively_regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +created_by: mah +creation_date: 2010-11-03T03:16:10Z + +[Term] +id: GO:0072337 +name: modified amino acid transport +namespace: biological_process +def: "The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "amino acid derivative transport" EXACT [] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: mah +creation_date: 2010-11-04T12:18:23Z + +[Term] +id: GO:0072338 +name: cellular lactam metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:mah] +synonym: "cellular lactam metabolism" EXACT [GOC:mah] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0044281 ! small molecule metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: mah +creation_date: 2010-11-04T04:31:21Z + +[Term] +id: GO:0072339 +name: cellular lactam biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:mah] +synonym: "cellular lactam anabolism" EXACT [GOC:mah] +synonym: "cellular lactam biosynthesis" EXACT [GOC:mah] +synonym: "cellular lactam formation" EXACT [GOC:mah] +synonym: "cellular lactam synthesis" EXACT [GOC:mah] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0072338 ! cellular lactam metabolic process +created_by: mah +creation_date: 2010-11-04T04:33:01Z + +[Term] +id: GO:0072340 +name: cellular lactam catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." [GOC:mah] +synonym: "cellular lactam breakdown" EXACT [GOC:mah] +synonym: "cellular lactam catabolism" EXACT [GOC:mah] +synonym: "cellular lactam degradation" EXACT [GOC:mah] +is_a: GO:0043605 ! cellular amide catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072338 ! cellular lactam metabolic process +created_by: mah +creation_date: 2010-11-04T04:33:22Z + +[Term] +id: GO:0072341 +name: modified amino acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a modified amino acid." [GOC:mah] +synonym: "amino acid derivative binding" EXACT [] +is_a: GO:0005488 ! binding +created_by: mah +creation_date: 2010-11-04T05:45:32Z + +[Term] +id: GO:0072342 +name: response to anion stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment." [GOC:cvs, PMID:19641131] +is_a: GO:0009651 ! response to salt stress +created_by: mah +creation_date: 2010-11-05T02:25:28Z + +[Term] +id: GO:0072343 +name: pancreatic stellate cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus." [CL:0002410, GOC:mah, PMID:17200706] +is_a: GO:0048144 ! fibroblast proliferation +created_by: mah +creation_date: 2010-11-05T03:04:50Z + +[Term] +id: GO:0072344 +name: rescue of stalled ribosome +namespace: biological_process +def: "A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex." [GOC:jh2, GOC:mah, PMID:18557701, PMID:19170872, PMID:20117091, PMID:20185543] +is_a: GO:0006414 ! translational elongation +is_a: GO:0006417 ! regulation of translation +created_by: mah +creation_date: 2010-11-10T11:54:26Z + +[Term] +id: GO:0072345 +name: NAADP-sensitive calcium-release channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts." [PMID:19387438, PMID:19557428] +xref: Reactome:R-HSA-2685505 "TPCN1/2 transport lysosomal Ca2+ to cytosol" +is_a: GO:0015278 ! calcium-release channel activity +created_by: mah +creation_date: 2010-11-10T01:03:35Z + +[Term] +id: GO:0072346 +name: cADPR-sensitive calcium-release channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts." [PMID:11752598] +is_a: GO:0015278 ! calcium-release channel activity +created_by: mah +creation_date: 2010-11-10T01:10:51Z + +[Term] +id: GO:0072347 +name: response to anesthetic +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation." [GOC:sart] +synonym: "response to anaesthetic" EXACT [GOC:mah] +is_a: GO:0042493 ! response to drug +created_by: mah +creation_date: 2010-11-10T01:26:18Z + +[Term] +id: GO:0072348 +name: sulfur compound transport +namespace: biological_process +def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] +synonym: "sulfur-containing compound transport" EXACT [GOC:mah] +is_a: GO:0006810 ! transport +created_by: mah +creation_date: 2010-11-11T11:43:56Z + +[Term] +id: GO:0072349 +name: modified amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of modified amino acids from one side of a membrane to the other." [GOC:mah] +synonym: "amino acid derivative transmembrane transporter activity" EXACT [] +synonym: "modified amino acid transporter activity" BROAD [GOC:mah] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0072337 ! modified amino acid transport +created_by: mah +creation_date: 2010-11-11T11:50:31Z + +[Term] +id: GO:0072350 +name: tricarboxylic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-)." [GOC:mah] +synonym: "tricarboxylic acid metabolism" EXACT [GOC:mah] +is_a: GO:0019752 ! carboxylic acid metabolic process +created_by: mah +creation_date: 2010-11-11T05:07:30Z + +[Term] +id: GO:0072351 +name: tricarboxylic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups." [GOC:mah] +synonym: "tricarboxylate biosynthesis" EXACT [GOC:mah] +synonym: "tricarboxylate biosynthetic process" EXACT [GOC:mah] +synonym: "tricarboxylic acid anabolism" EXACT [GOC:mah] +synonym: "tricarboxylic acid biosynthesis" EXACT [GOC:mah] +synonym: "tricarboxylic acid formation" EXACT [GOC:mah] +synonym: "tricarboxylic acid synthesis" EXACT [GOC:mah] +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +created_by: mah +creation_date: 2010-11-11T05:08:54Z + +[Term] +id: GO:0072352 +name: tricarboxylic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups." [GOC:mah] +synonym: "tricarboxylate catabolic process" EXACT [GOC:mah] +synonym: "tricarboxylate catabolism" EXACT [GOC:mah] +synonym: "tricarboxylic acid breakdown" EXACT [GOC:mah] +synonym: "tricarboxylic acid catabolism" EXACT [GOC:mah] +synonym: "tricarboxylic acid degradation" EXACT [GOC:mah] +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0072350 ! tricarboxylic acid metabolic process +created_by: mah +creation_date: 2010-11-11T05:11:24Z + +[Term] +id: GO:0072353 +name: cellular age-dependent response to reactive oxygen species +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism." [GOC:mah] +is_a: GO:0001315 ! age-dependent response to reactive oxygen species +is_a: GO:0034614 ! cellular response to reactive oxygen species +created_by: mah +creation_date: 2010-11-12T11:27:27Z + +[Term] +id: GO:0072354 +name: histone kinase activity (H3-T3 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3." [GOC:mah] +synonym: "histone threonine kinase activity (H3-T3 specific)" EXACT [GOC:mah] +synonym: "histone-threonine kinase activity (H3-T3 specific)" EXACT [GOC:mah] +is_a: GO:0035184 ! histone threonine kinase activity +relationship: part_of GO:0072355 ! histone H3-T3 phosphorylation +created_by: mah +creation_date: 2010-11-12T04:27:57Z + +[Term] +id: GO:0072355 +name: histone H3-T3 phosphorylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone." [GOC:mah] +is_a: GO:0035405 ! histone-threonine phosphorylation +created_by: mah +creation_date: 2010-11-12T04:28:56Z + +[Term] +id: GO:0072356 +name: chromosome passenger complex localization to kinetochore +namespace: biological_process +def: "A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis." [GOC:mah] +synonym: "chromosomal passenger complex localization to kinetochore" EXACT [GOC:mah] +synonym: "chromosome passenger complex localisation to kinetochore" RELATED [GOC:mah] +synonym: "CPC complex localization to kinetochore" EXACT [GOC:vw] +synonym: "CPC localization to kinetochore" EXACT [GOC:mah] +is_a: GO:0034501 ! protein localization to kinetochore +is_a: GO:0034629 ! cellular protein-containing complex localization +created_by: mah +creation_date: 2010-11-15T11:30:38Z + +[Term] +id: GO:0072357 +name: PTW/PP1 phosphatase complex +namespace: cellular_component +def: "A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase." [GOC:mah, PMID:20516061] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +created_by: mah +creation_date: 2010-11-15T03:32:27Z + +[Term] +id: GO:0072358 +name: cardiovascular system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels." [GOC:mah, UBERON:0004535] +is_a: GO:0048731 ! system development +relationship: part_of GO:0072359 ! circulatory system development +created_by: mah +creation_date: 2010-11-16T11:25:49Z + +[Term] +id: GO:0072359 +name: circulatory system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009] +is_a: GO:0048731 ! system development +created_by: mah +creation_date: 2010-11-16T11:27:39Z + +[Term] +id: GO:0072360 +name: vascular cord development +namespace: biological_process +def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0072358 ! cardiovascular system development +created_by: mah +creation_date: 2010-11-16T11:46:55Z + +[Term] +id: GO:0072361 +name: obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T02:57:18Z + +[Term] +id: GO:0072362 +name: obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: The reason for obsoletion is that this term represented a GO-CAM model. +synonym: "regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T02:59:32Z + +[Term] +id: GO:0072363 +name: obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:08:25Z + +[Term] +id: GO:0072364 +name: obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +synonym: "regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:11:39Z + +[Term] +id: GO:0072365 +name: obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +synonym: "regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:12:09Z + +[Term] +id: GO:0072366 +name: obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +synonym: "regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:12:47Z + +[Term] +id: GO:0072367 +name: obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:17:54Z + +[Term] +id: GO:0072368 +name: obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:18:13Z + +[Term] +id: GO:0072369 +name: obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:mah] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter" EXACT [GOC:bf] +is_obsolete: true +created_by: mah +creation_date: 2010-11-16T03:23:53Z + +[Term] +id: GO:0072370 +name: histone H2A-S121 phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone." [GOC:mah, PMID:19965387] +synonym: "histone H2A phosphorylation at S121" EXACT [GOC:mah] +synonym: "histone H2AS121 phosphorylation" EXACT [GOC:mah] +is_a: GO:0035404 ! histone-serine phosphorylation +is_a: GO:1990164 ! histone H2A phosphorylation +created_by: mah +creation_date: 2010-11-16T03:42:52Z + +[Term] +id: GO:0072371 +name: histone kinase activity (H2A-S121 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A." [GOC:mah, PMID:19965387] +synonym: "histone serine kinase activity (H2A-S121 specific)" EXACT [GOC:mah] +synonym: "histone-serine kinase activity (H2A-S121 specific)" EXACT [GOC:mah] +is_a: GO:0035174 ! histone serine kinase activity +relationship: part_of GO:0072370 ! histone H2A-S121 phosphorylation +created_by: mah +creation_date: 2010-11-16T03:42:59Z + +[Term] +id: GO:0072373 +name: alpha-carotene epsilon hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O." [GOC:mah, MetaCyc:CPD-7421, MetaCyc:CPD1F-118, MetaCyc:RXN-5962] +xref: EC:1.14.99 +is_a: GO:0072374 ! carotene epsilon hydroxylase activity +created_by: mah +creation_date: 2010-11-19T03:52:25Z + +[Term] +id: GO:0072374 +name: carotene epsilon hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene." [GOC:mah, MetaCyc:CPD-7421, MetaCyc:CPD1F-118, MetaCyc:RXN-5962] +xref: EC:1.14.99 +is_a: GO:0004497 ! monooxygenase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: mah +creation_date: 2010-11-19T03:57:55Z + +[Term] +id: GO:0072375 +name: medium-term memory +namespace: biological_process +def: "The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster)." [GOC:sart, PMID:14659098, PMID:7923375] +synonym: "middle-term memory" EXACT [GOC:sart] +synonym: "MTM" NARROW [GOC:sart] +is_a: GO:0007613 ! memory +created_by: mah +creation_date: 2010-11-22T11:26:54Z + +[Term] +id: GO:0072376 +name: protein activation cascade +namespace: biological_process +def: "A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events." [GOC:add, GOC:mah, GOC:pde] +synonym: "protein activation pathway" EXACT [GOC:add] +synonym: "protein activitory cascade" EXACT [GOC:add] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0050896 ! response to stimulus +created_by: mah +creation_date: 2010-11-22T02:54:18Z + +[Term] +id: GO:0072377 +name: blood coagulation, common pathway +namespace: biological_process +def: "A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex." [GOC:add, GOC:mah, GOC:pde, PMID:1931959] +comment: See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'. +is_a: GO:0072376 ! protein activation cascade +relationship: part_of GO:0072378 ! blood coagulation, fibrin clot formation +created_by: mah +creation_date: 2010-11-22T03:01:12Z + +[Term] +id: GO:0072378 +name: blood coagulation, fibrin clot formation +namespace: biological_process +def: "A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events." [GOC:add, GOC:mah, GOC:pde] +comment: See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'. +is_a: GO:0072376 ! protein activation cascade +relationship: part_of GO:0007596 ! blood coagulation +created_by: mah +creation_date: 2010-11-22T03:09:32Z + +[Term] +id: GO:0072379 +name: ER membrane insertion complex +namespace: cellular_component +def: "A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast." [GOC:mah, PMID:20676083, PMID:20850366] +synonym: "endoplasmic reticulum membrane insertion complex" EXACT [GOC:mah] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: mah +creation_date: 2010-11-24T02:07:09Z + +[Term] +id: GO:0072380 +name: TRC complex +namespace: cellular_component +def: "An ER membrane insertion complex that contains subunits that recognize two types of transmembrane domain signals. In budding yeast the complex contains Get4p, Get5p, Sgt2p, and at least two heat shock proteins (HSPs)." [GOC:mah, PMID:20850366] +synonym: "TMD recognition complex" EXACT [PMID:20850366] +is_a: GO:0072379 ! ER membrane insertion complex +created_by: mah +creation_date: 2010-11-24T02:43:41Z + +[Term] +id: GO:0072381 +name: positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:mah] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation" EXACT [] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation" EXACT [GOC:mah] +synonym: "positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation" EXACT [GOC:signaling] +synonym: "positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation" EXACT [GOC:mah] +is_a: GO:0072335 ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation +is_a: GO:0090263 ! positive regulation of canonical Wnt signaling pathway +is_a: GO:1905294 ! positive regulation of neural crest cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +relationship: positively_regulates GO:0044335 ! canonical Wnt signaling pathway involved in neural crest cell differentiation +created_by: mah +creation_date: 2010-11-24T03:10:15Z + +[Term] +id: GO:0072382 +name: minus-end-directed vesicle transport along microtubule +namespace: biological_process +def: "The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:BHF, GOC:mah] +synonym: "microtubule minus-end-directed vesicle distribution" NARROW [GOC:rl] +synonym: "microtubule minus-end-directed vesicle localization" EXACT [GOC:rl] +is_a: GO:0047496 ! vesicle transport along microtubule +is_a: GO:0072385 ! minus-end-directed organelle transport along microtubule +created_by: mah +creation_date: 2010-12-01T04:12:59Z + +[Term] +id: GO:0072383 +name: plus-end-directed vesicle transport along microtubule +namespace: biological_process +def: "The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:BHF, GOC:mah] +synonym: "microtubule plus-end-directed vesicle distribution" NARROW [GOC:rl] +synonym: "microtubule plus-end-directed vesicle localization" EXACT [GOC:rl] +is_a: GO:0047496 ! vesicle transport along microtubule +is_a: GO:0072386 ! plus-end-directed organelle transport along microtubule +created_by: mah +creation_date: 2010-12-01T04:24:51Z + +[Term] +id: GO:0072384 +name: organelle transport along microtubule +namespace: biological_process +def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah] +synonym: "microtubule-based organelle localization" EXACT [GOC:rl] +is_a: GO:0010970 ! transport along microtubule +is_a: GO:0051656 ! establishment of organelle localization +created_by: mah +creation_date: 2010-12-01T04:59:11Z + +[Term] +id: GO:0072385 +name: minus-end-directed organelle transport along microtubule +namespace: biological_process +def: "The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:BHF, GOC:mah] +synonym: "microtubule minus-end-directed organelle distribution" NARROW [GOC:rl] +synonym: "microtubule minus-end-directed organelle localization" EXACT [GOC:rl] +is_a: GO:0072384 ! organelle transport along microtubule +created_by: mah +creation_date: 2010-12-01T05:01:20Z + +[Term] +id: GO:0072386 +name: plus-end-directed organelle transport along microtubule +namespace: biological_process +def: "The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:BHF, GOC:mah] +synonym: "microtubule plus-end-directed organelle distribution" NARROW [GOC:rl] +synonym: "microtubule plus-end-directed organelle localization" EXACT [GOC:rl] +is_a: GO:0072384 ! organelle transport along microtubule +created_by: mah +creation_date: 2010-12-01T05:02:09Z + +[Term] +id: GO:0072387 +name: flavin adenine dinucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah] +synonym: "FAD or FADH2 metabolic process" EXACT [] +synonym: "flavin adenine dinucleotide metabolism" EXACT [] +synonym: "flavin-adenine dinucleotide metabolic process" EXACT [] +is_a: GO:0006732 ! coenzyme metabolic process +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0042726 ! flavin-containing compound metabolic process +created_by: mah +creation_date: 2010-12-02T04:21:43Z + +[Term] +id: GO:0072388 +name: flavin adenine dinucleotide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah] +synonym: "FAD or FADH2 biosynthetic process" EXACT [] +synonym: "flavin adenine dinucleotide anabolism" EXACT [] +synonym: "flavin adenine dinucleotide biosynthesis" EXACT [] +synonym: "flavin adenine dinucleotide formation" EXACT [] +synonym: "flavin adenine dinucleotide synthesis" EXACT [] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:0042727 ! flavin-containing compound biosynthetic process +is_a: GO:0072387 ! flavin adenine dinucleotide metabolic process +created_by: mah +creation_date: 2010-12-02T04:26:34Z + +[Term] +id: GO:0072389 +name: flavin adenine dinucleotide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:mah] +synonym: "FAD or FADH2 catabolic process" EXACT [] +synonym: "flavin adenine dinucleotide breakdown" EXACT [] +synonym: "flavin adenine dinucleotide catabolism" EXACT [] +synonym: "flavin adenine dinucleotide degradation" EXACT [] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0009166 ! nucleotide catabolic process +is_a: GO:0042728 ! flavin-containing compound catabolic process +is_a: GO:0072387 ! flavin adenine dinucleotide metabolic process +created_by: mah +creation_date: 2010-12-02T04:28:02Z + +[Term] +id: GO:0072390 +name: phenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group." [GOC:mah] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +created_by: mah +creation_date: 2010-12-06T04:05:51Z + +[Term] +id: GO:0072391 +name: phenol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group." [GOC:mah] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072390 ! phenol metabolic process +created_by: mah +creation_date: 2010-12-06T04:08:04Z + +[Term] +id: GO:0072392 +name: phenol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group." [GOC:mah] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072390 ! phenol metabolic process +created_by: mah +creation_date: 2010-12-06T04:08:44Z + +[Term] +id: GO:0072393 +name: microtubule anchoring at microtubule organizing center +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center." [GOC:BHF, PMID:19825938] +synonym: "microtubule anchoring at microtubule organising centre" EXACT [GOC:mah] +synonym: "microtubule anchoring at MTOC" EXACT [GOC:BHF] +is_a: GO:0034453 ! microtubule anchoring +created_by: mah +creation_date: 2010-12-07T11:54:35Z + +[Term] +id: GO:0072394 +name: detection of stimulus involved in cell cycle checkpoint +namespace: biological_process +alt_id: GO:0072403 +alt_id: GO:0072406 +def: "The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint." [GOC:mtg_cell_cycle] +synonym: "cell cycle checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "cell cycle checkpoint sensor process" RELATED [GOC:mah] +synonym: "detection of stimulus involved in G1/S transition checkpoint" RELATED [] +synonym: "detection of stimulus involved in G2/M transition checkpoint" RELATED [] +synonym: "G1/S transition checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "G1/S transition checkpoint sensor process" RELATED [GOC:mah] +synonym: "G2/M transition checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "G2/M transition checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in cell cycle checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in G1/S transition checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in G2/M transition checkpoint" RELATED [GOC:mah] +is_a: GO:0090429 ! detection of endogenous biotic stimulus +intersection_of: GO:0090429 ! detection of endogenous biotic stimulus +intersection_of: part_of GO:0000075 ! cell cycle checkpoint +relationship: part_of GO:0000075 ! cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T02:55:56Z + +[Term] +id: GO:0072395 +name: signal transduction involved in cell cycle checkpoint +namespace: biological_process +alt_id: GO:0072404 +alt_id: GO:0072407 +def: "A signal transduction process that contributes to a cell cycle checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in G2/M transition checkpoint" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0000075 ! cell cycle checkpoint +relationship: part_of GO:0000075 ! cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T02:59:45Z + +[Term] +id: GO:0072396 +name: response to cell cycle checkpoint signaling +namespace: biological_process +alt_id: GO:0072405 +alt_id: GO:0072408 +def: "A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "cell cycle checkpoint effector process" EXACT [GOC:mah] +synonym: "G1/S transition checkpoint effector process" RELATED [GOC:mah] +synonym: "G2/M transition checkpoint effector process" RELATED [GOC:mah] +synonym: "response to G1/S transition checkpoint signaling" RELATED [] +synonym: "response to G2/M transition checkpoint signaling" RELATED [] +synonym: "response to signal involved in cell cycle checkpoint" EXACT [GOC:mah] +synonym: "response to signal involved in G1/S transition checkpoint" RELATED [GOC:mah] +synonym: "response to signal involved in G2/M transition checkpoint" RELATED [GOC:mah] +is_a: GO:0071216 ! cellular response to biotic stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +created_by: mah +creation_date: 2010-12-08T03:05:46Z + +[Term] +id: GO:0072397 +name: detection of stimulus involved in cytokinesis checkpoint +namespace: biological_process +alt_id: GO:0072418 +def: "The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint." [GOC:mtg_cell_cycle] +synonym: "cytokinesis checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "cytokinesis checkpoint sensor process" RELATED [GOC:mah] +synonym: "detection of stimulus involved in septin checkpoint" RELATED [] +synonym: "sensing involved in cytokinesis checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in septin checkpoint" RELATED [GOC:mah] +synonym: "septin checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "septin checkpoint sensor process" RELATED [GOC:mah] +is_a: GO:0072412 ! detection of stimulus involved in mitotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:18:11Z + +[Term] +id: GO:0072398 +name: signal transduction involved in cytokinesis checkpoint +namespace: biological_process +alt_id: GO:0072419 +def: "A signal transduction process that contributes to a cytokinesis checkpoint." [GOC:mtg_cell_cycle] +is_a: GO:0072413 ! signal transduction involved in mitotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:22:21Z + +[Term] +id: GO:0072399 +name: response to cytokinesis checkpoint signaling +namespace: biological_process +alt_id: GO:0072420 +def: "A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "cytokinesis checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in cytokinesis checkpoint" EXACT [GOC:mah] +is_a: GO:0072396 ! response to cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-08T03:23:32Z + +[Term] +id: GO:0072400 +name: detection of stimulus involved in mitotic DNA integrity checkpoint +namespace: biological_process +alt_id: GO:0072457 +def: "The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in mitotic G2/M transition decatenation checkpoint" RELATED [] +synonym: "DNA integrity checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "DNA integrity checkpoint sensor process" RELATED [GOC:mah] +synonym: "mitotic G2/M transition decatenation checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic G2/M transition decatenation checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in DNA integrity checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in mitotic G2/M transition decatenation checkpoint" RELATED [GOC:mah] +is_a: GO:0072412 ! detection of stimulus involved in mitotic cell cycle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044774 ! mitotic DNA integrity checkpoint +relationship: part_of GO:0044774 ! mitotic DNA integrity checkpoint +created_by: mah +creation_date: 2010-12-08T03:29:11Z + +[Term] +id: GO:0072401 +name: signal transduction involved in DNA integrity checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a DNA integrity checkpoint." [GOC:mah] +is_a: GO:0072395 ! signal transduction involved in cell cycle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031570 ! DNA integrity checkpoint +relationship: part_of GO:0031570 ! DNA integrity checkpoint +created_by: mah +creation_date: 2010-12-08T03:31:56Z + +[Term] +id: GO:0072402 +name: response to DNA integrity checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "DNA integrity checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in DNA integrity checkpoint" EXACT [GOC:mah] +is_a: GO:0072396 ! response to cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-08T03:32:17Z + +[Term] +id: GO:0072409 +name: detection of stimulus involved in meiotic cell cycle checkpoint +namespace: biological_process +def: "The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint." [GOC:mah, GOC:mtg_cell_cycle] +synonym: "meiotic cell cycle checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "meiotic cell cycle checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in meiotic cell cycle checkpoint" RELATED [GOC:mah] +is_a: GO:0022414 ! reproductive process +is_a: GO:0072394 ! detection of stimulus involved in cell cycle checkpoint +intersection_of: GO:0090429 ! detection of endogenous biotic stimulus +intersection_of: part_of GO:0033313 ! meiotic cell cycle checkpoint +relationship: part_of GO:0033313 ! meiotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:47:50Z + +[Term] +id: GO:0072410 +name: response to meiotic cell cycle checkpoint signaling +namespace: biological_process +def: "A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint." [GOC:mah] +synonym: "meiotic cell cycle checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in meiotic cell cycle checkpoint" EXACT [GOC:mah] +is_a: GO:0072396 ! response to cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-08T03:48:38Z + +[Term] +id: GO:0072411 +name: signal transduction involved in meiotic cell cycle checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a meiotic cell cycle checkpoint." [GOC:mah] +is_a: GO:0072395 ! signal transduction involved in cell cycle checkpoint +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0033313 ! meiotic cell cycle checkpoint +relationship: part_of GO:0033313 ! meiotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:48:45Z + +[Term] +id: GO:0072412 +name: detection of stimulus involved in mitotic cell cycle checkpoint +namespace: biological_process +alt_id: GO:0072454 +alt_id: GO:0072472 +def: "The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in mitotic cell cycle G1/S checkpoint" RELATED [] +synonym: "mitotic cell cycle checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle checkpoint sensor process" RELATED [GOC:mah] +synonym: "mitotic cell cycle G1/S checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle G1/S checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle G1/S checkpoint" RELATED [GOC:mah] +is_a: GO:0072394 ! detection of stimulus involved in cell cycle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0007093 ! mitotic cell cycle checkpoint +relationship: part_of GO:0007093 ! mitotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:48:57Z + +[Term] +id: GO:0072413 +name: signal transduction involved in mitotic cell cycle checkpoint +namespace: biological_process +alt_id: GO:0072456 +alt_id: GO:0072474 +def: "A signal transduction process that contributes to a mitotic cell cycle checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in mitotic cell cycle G1/S checkpoint" RELATED [] +synonym: "signal transduction involved in mitotic G2/M transition checkpoint" RELATED [] +is_a: GO:0072395 ! signal transduction involved in cell cycle checkpoint +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0007093 ! mitotic cell cycle checkpoint +relationship: part_of GO:0007093 ! mitotic cell cycle checkpoint +created_by: mah +creation_date: 2010-12-08T03:50:28Z + +[Term] +id: GO:0072414 +name: response to mitotic cell cycle checkpoint signaling +namespace: biological_process +alt_id: GO:0072455 +alt_id: GO:0072473 +def: "A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle checkpoint effector process" EXACT [GOC:mah] +synonym: "mitotic cell cycle G1/S checkpoint effector process" RELATED [GOC:mah] +synonym: "mitotic G2/M transition checkpoint effector process" RELATED [GOC:mah] +synonym: "response to mitotic cell cycle G1/S checkpoint signaling" RELATED [] +synonym: "response to mitotic G2/M transition checkpoint signal" RELATED [] +synonym: "response to signal involved in mitotic cell cycle checkpoint" RELATED [GOC:mah] +synonym: "response to signal involved in mitotic cell cycle G1/S checkpoint" RELATED [GOC:mah] +synonym: "response to signal involved in mitotic G2/M transition checkpoint" RELATED [GOC:mah] +is_a: GO:0072396 ! response to cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-08T03:50:43Z + +[Term] +id: GO:0072415 +name: detection of stimulus involved in spindle checkpoint +namespace: biological_process +def: "The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint." [GOC:mah, GOC:mtg_cell_cycle] +synonym: "sensing involved in spindle checkpoint" RELATED [GOC:mah] +synonym: "spindle checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "spindle checkpoint sensor process" RELATED [GOC:mah] +is_a: GO:0072394 ! detection of stimulus involved in cell cycle checkpoint +intersection_of: GO:0090429 ! detection of endogenous biotic stimulus +intersection_of: part_of GO:0031577 ! spindle checkpoint +relationship: part_of GO:0031577 ! spindle checkpoint +created_by: mah +creation_date: 2010-12-08T03:54:50Z + +[Term] +id: GO:0072416 +name: signal transduction involved in spindle checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a spindle checkpoint." [GOC:mah] +is_a: GO:0072395 ! signal transduction involved in cell cycle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031577 ! spindle checkpoint +relationship: part_of GO:0031577 ! spindle checkpoint +created_by: mah +creation_date: 2010-12-08T03:55:51Z + +[Term] +id: GO:0072417 +name: response to spindle checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of spindle checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "response to signal involved in spindle checkpoint" EXACT [GOC:mah] +synonym: "spindle checkpoint effector process" EXACT [GOC:mah] +is_a: GO:0072396 ! response to cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-08T03:56:04Z + +[Term] +id: GO:0072421 +name: detection of DNA damage stimulus involved in DNA damage checkpoint +namespace: biological_process +def: "The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "DNA damage checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "DNA damage checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in DNA damage checkpoint" RELATED [GOC:mah] +is_a: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: part_of GO:0000077 ! DNA damage checkpoint +relationship: part_of GO:0000077 ! DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:16:04Z + +[Term] +id: GO:0072422 +name: signal transduction involved in DNA damage checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a DNA damage checkpoint." [GOC:mah] +is_a: GO:0042770 ! signal transduction in response to DNA damage +is_a: GO:0072401 ! signal transduction involved in DNA integrity checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0000077 ! DNA damage checkpoint +relationship: part_of GO:0000077 ! DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:18:11Z + +[Term] +id: GO:0072423 +name: response to DNA damage checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "DNA damage checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in DNA damage checkpoint" EXACT [GOC:mah] +is_a: GO:0072402 ! response to DNA integrity checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:20:25Z + +[Term] +id: GO:0072424 +name: detection of DNA damage stimulus involved in G2 DNA damage checkpoint +namespace: biological_process +def: "The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a G2/M transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of DNA damage stimulus involved in G2/M transition DNA damage checkpoint" EXACT [] +synonym: "G2/M transition DNA damage checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "G2/M transition DNA damage checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in G2/M transition DNA damage checkpoint" RELATED [GOC:mah] +is_a: GO:0072421 ! detection of DNA damage stimulus involved in DNA damage checkpoint +intersection_of: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: part_of GO:0031572 ! G2 DNA damage checkpoint +relationship: part_of GO:0031572 ! G2 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:24:59Z + +[Term] +id: GO:0072425 +name: signal transduction involved in G2 DNA damage checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a G2/M transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in G2/M transition DNA damage checkpoint" EXACT [] +is_a: GO:0072422 ! signal transduction involved in DNA damage checkpoint +is_a: GO:1902750 ! negative regulation of cell cycle G2/M phase transition +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031572 ! G2 DNA damage checkpoint +relationship: part_of GO:0031572 ! G2 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:25:26Z + +[Term] +id: GO:0072426 +name: response to G2 DNA damage checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "G2/M transition DNA damage checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:mah] +is_a: GO:0072423 ! response to DNA damage checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:26:35Z + +[Term] +id: GO:0072427 +name: detection of DNA damage stimulus involved in intra-S DNA damage checkpoint +namespace: biological_process +def: "The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint." [GOC:mah] +synonym: "intra-S DNA damage checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "intra-S DNA damage checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in intra-S DNA damage checkpoint" RELATED [GOC:mah] +is_a: GO:0072421 ! detection of DNA damage stimulus involved in DNA damage checkpoint +is_a: GO:1902401 ! detection of stimulus involved in mitotic DNA damage checkpoint +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: part_of GO:0031573 ! intra-S DNA damage checkpoint +relationship: part_of GO:0031573 ! intra-S DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:30:27Z + +[Term] +id: GO:0072428 +name: signal transduction involved in intra-S DNA damage checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to an intra-S DNA damage checkpoint." [GOC:mah] +is_a: GO:1902402 ! signal transduction involved in mitotic DNA damage checkpoint +is_a: GO:1903464 ! negative regulation of mitotic cell cycle DNA replication +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031573 ! intra-S DNA damage checkpoint +relationship: part_of GO:0031573 ! intra-S DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:31:08Z + +[Term] +id: GO:0072429 +name: response to intra-S DNA damage checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "intra-S DNA damage checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in intra-S DNA damage checkpoint" EXACT [GOC:mah] +is_a: GO:0072423 ! response to DNA damage checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:31:56Z + +[Term] +id: GO:0072430 +name: detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint +namespace: biological_process +def: "The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of DNA damage stimulus involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [] +synonym: "mitotic cell cycle G1/S transition DNA damage checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle G1/S transition DNA damage checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle G1/S transition DNA damage checkpoint" RELATED [GOC:mah] +is_a: GO:0072421 ! detection of DNA damage stimulus involved in DNA damage checkpoint +is_a: GO:1902399 ! detection of stimulus involved in G1 DNA damage checkpoint +is_a: GO:1902401 ! detection of stimulus involved in mitotic DNA damage checkpoint +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: part_of GO:0031571 ! mitotic G1 DNA damage checkpoint +relationship: part_of GO:0031571 ! mitotic G1 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:37:40Z + +[Term] +id: GO:0072431 +name: signal transduction involved in mitotic G1 DNA damage checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [] +is_a: GO:1902400 ! intracellular signal transduction involved in G1 DNA damage checkpoint +is_a: GO:1902402 ! signal transduction involved in mitotic DNA damage checkpoint +is_a: GO:2000134 ! negative regulation of G1/S transition of mitotic cell cycle +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031571 ! mitotic G1 DNA damage checkpoint +relationship: part_of GO:0031571 ! mitotic G1 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:37:55Z + +[Term] +id: GO:0072432 +name: response to G1 DNA damage checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:mah] +synonym: "response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [] +synonym: "response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:mah] +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +is_a: GO:0072423 ! response to DNA damage checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:38:04Z + +[Term] +id: GO:0072433 +name: detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of DNA damage stimulus involved in mitotic G2/M transition DNA damage checkpoint" EXACT [] +synonym: "mitotic G2/M transition DNA damage checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic G2/M transition DNA damage checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic G2/M transition DNA damage checkpoint" RELATED [GOC:mah] +is_a: GO:0072424 ! detection of DNA damage stimulus involved in G2 DNA damage checkpoint +is_a: GO:1902401 ! detection of stimulus involved in mitotic DNA damage checkpoint +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: part_of GO:0007095 ! mitotic G2 DNA damage checkpoint +relationship: part_of GO:0007095 ! mitotic G2 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:43:14Z + +[Term] +id: GO:0072434 +name: signal transduction involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a mitotic G2/M transition DNA damage checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [] +is_a: GO:0010972 ! negative regulation of G2/M transition of mitotic cell cycle +is_a: GO:0072425 ! signal transduction involved in G2 DNA damage checkpoint +is_a: GO:1902402 ! signal transduction involved in mitotic DNA damage checkpoint +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0007095 ! mitotic G2 DNA damage checkpoint +relationship: part_of GO:0007095 ! mitotic G2 DNA damage checkpoint +created_by: mah +creation_date: 2010-12-08T04:43:48Z + +[Term] +id: GO:0072435 +name: response to mitotic G2 DNA damage checkpoint signaling +namespace: biological_process +alt_id: GO:0072458 +def: "A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic G2/M transition decatenation checkpoint effector process" RELATED [GOC:mah] +synonym: "mitotic G2/M transition DNA damage checkpoint effector process" EXACT [GOC:mah] +synonym: "response to mitotic G2/M transition decatenation checkpoint signaling" RELATED [] +synonym: "response to mitotic G2/M transition DNA damage checkpoint signaling" EXACT [] +synonym: "response to signal involved in mitotic G2/M transition decatenation checkpoint" RELATED [GOC:mah] +synonym: "response to signal involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:mah] +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +is_a: GO:0072426 ! response to G2 DNA damage checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:44:01Z + +[Term] +id: GO:0072436 +name: detection of stimulus involved in DNA replication checkpoint +namespace: biological_process +def: "The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint." [GOC:mtg_cell_cycle] +synonym: "DNA replication checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "DNA replication checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in DNA replication checkpoint" RELATED [GOC:mah] +is_a: GO:0042769 ! DNA damage response, detection of DNA damage +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0000076 ! DNA replication checkpoint +relationship: part_of GO:0000076 ! DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T04:52:09Z + +[Term] +id: GO:0072437 +name: signal transduction involved in DNA replication checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a DNA replication checkpoint." [GOC:mah] +is_a: GO:0072401 ! signal transduction involved in DNA integrity checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0000076 ! DNA replication checkpoint +relationship: part_of GO:0000076 ! DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T04:52:31Z + +[Term] +id: GO:0072438 +name: response to DNA replication checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "DNA replication checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in DNA replication checkpoint" EXACT [GOC:mah] +is_a: GO:0072402 ! response to DNA integrity checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:53:12Z + +[Term] +id: GO:0072439 +name: detection of stimulus involved in meiotic DNA replication checkpoint +namespace: biological_process +def: "The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint." [GOC:mtg_cell_cycle] +synonym: "meiotic DNA replication checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "meiotic DNA replication checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in meiotic DNA replication checkpoint" RELATED [GOC:mah] +is_a: GO:0072436 ! detection of stimulus involved in DNA replication checkpoint +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0033315 ! meiotic G2/MI DNA replication checkpoint +relationship: part_of GO:0033315 ! meiotic G2/MI DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T04:59:08Z + +[Term] +id: GO:0072440 +name: signal transduction involved in meiotic DNA replication checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a meiotic DNA replication checkpoint." [GOC:mah] +is_a: GO:0072411 ! signal transduction involved in meiotic cell cycle checkpoint +is_a: GO:0072437 ! signal transduction involved in DNA replication checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0033315 ! meiotic G2/MI DNA replication checkpoint +relationship: part_of GO:0033315 ! meiotic G2/MI DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T04:59:18Z + +[Term] +id: GO:0072441 +name: response to meiotic DNA replication checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "meiotic DNA replication checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in meiotic DNA replication checkpoint" EXACT [GOC:mah] +is_a: GO:0072410 ! response to meiotic cell cycle checkpoint signaling +is_a: GO:0072438 ! response to DNA replication checkpoint signaling +created_by: mah +creation_date: 2010-12-08T04:59:26Z + +[Term] +id: GO:0072442 +name: detection of stimulus involved in mitotic DNA replication checkpoint +namespace: biological_process +alt_id: GO:0072445 +def: "The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in S-M checkpoint" RELATED [] +synonym: "mitotic DNA replication checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic DNA replication checkpoint sensor process" RELATED [GOC:mah] +synonym: "S-M checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "S-M checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic DNA replication checkpoint" RELATED [GOC:mah] +synonym: "sensing involved in S-M checkpoint" RELATED [GOC:mah] +is_a: GO:0072400 ! detection of stimulus involved in mitotic DNA integrity checkpoint +is_a: GO:0072436 ! detection of stimulus involved in DNA replication checkpoint +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0033314 ! mitotic DNA replication checkpoint +relationship: part_of GO:0033314 ! mitotic DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T05:12:49Z + +[Term] +id: GO:0072443 +name: signal transduction involved in mitotic DNA replication checkpoint +namespace: biological_process +alt_id: GO:0072446 +alt_id: GO:0072459 +def: "A signal transduction process that contributes to a mitotic DNA replication checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in mitotic G2/M transition decatenation checkpoint" RELATED [] +synonym: "signal transduction involved in S-M checkpoint" EXACT [] +is_a: GO:0072437 ! signal transduction involved in DNA replication checkpoint +is_a: GO:1902403 ! signal transduction involved in mitotic DNA integrity checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0033314 ! mitotic DNA replication checkpoint +relationship: part_of GO:0033314 ! mitotic DNA replication checkpoint +created_by: mah +creation_date: 2010-12-08T05:12:56Z + +[Term] +id: GO:0072444 +name: response to mitotic DNA replication checkpoint signaling +namespace: biological_process +alt_id: GO:0072447 +def: "A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic DNA replication checkpoint effector process" EXACT [GOC:mah] +synonym: "response to S-M checkpoint signaling" EXACT [] +synonym: "response to signal involved in mitotic DNA replication checkpoint" EXACT [GOC:mah] +synonym: "response to signal involved in S-M checkpoint" EXACT [GOC:mah] +synonym: "S-M checkpoint effector process" EXACT [GOC:mah] +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +is_a: GO:0072438 ! response to DNA replication checkpoint signaling +created_by: mah +creation_date: 2010-12-08T05:13:27Z + +[Term] +id: GO:0072448 +name: detection of stimulus involved in G1 cell size control checkpoint +namespace: biological_process +def: "The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in mitotic cell cycle G1/S transition size control checkpoint" RELATED [] +synonym: "mitotic cell cycle G1/S transition size control checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle G1/S transition size control checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle G1/S transition size control checkpoint" RELATED [GOC:mah] +is_a: GO:0072469 ! detection of stimulus involved in cell size control checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0031568 ! G1 cell size control checkpoint +relationship: part_of GO:0031568 ! G1 cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T10:56:32Z + +[Term] +id: GO:0072449 +name: response to G1 cell size control checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle G1/S transition size control checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in mitotic cell cycle G1/S transition size control checkpoint" EXACT [GOC:mah] +is_a: GO:0072470 ! response to cell size control checkpoint signaling +created_by: mah +creation_date: 2010-12-09T10:56:39Z + +[Term] +id: GO:0072450 +name: signal transduction involved in G1 cell size control checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of mitosis." [GOC:mah] +synonym: "signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint" EXACT [] +is_a: GO:0072471 ! signal transduction involved in cell size control checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031568 ! G1 cell size control checkpoint +relationship: part_of GO:0031568 ! G1 cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T10:56:44Z + +[Term] +id: GO:0072451 +name: detection of stimulus involved in G2 cell size control checkpoint +namespace: biological_process +def: "The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in G2/M transition size control checkpoint" EXACT [] +synonym: "detection of stimulus involved in mitotic cell cycle G2/M transition size control checkpoint" RELATED [GOC:mah] +synonym: "G2/M transition size control checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "G2/M transition size control checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in G2/M transition size control checkpoint" RELATED [GOC:mah] +is_a: GO:0072469 ! detection of stimulus involved in cell size control checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0031569 ! mitotic G2 cell size control checkpoint +relationship: part_of GO:0031569 ! mitotic G2 cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T11:14:00Z + +[Term] +id: GO:0072452 +name: response to G2 transition size control checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "G2/M transition size control checkpoint effector process" EXACT [GOC:mah] +synonym: "response to G2/M transition size control checkpoint signaling" EXACT [] +synonym: "response to mitotic cell cycle G2/M transition size control checkpoint signaling" EXACT [GOC:mah] +synonym: "response to signal involved in G2/M transition size control checkpoint" EXACT [GOC:mah] +is_a: GO:0072470 ! response to cell size control checkpoint signaling +created_by: mah +creation_date: 2010-12-09T11:14:12Z + +[Term] +id: GO:0072453 +name: signal transduction involved in G2 cell size control checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a cell size control checkpoint during the G2/M transition of mitosis." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in G2/M transition size control checkpoint" EXACT [] +synonym: "signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint" EXACT [GOC:mah] +is_a: GO:0072471 ! signal transduction involved in cell size control checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031569 ! mitotic G2 cell size control checkpoint +relationship: part_of GO:0031569 ! mitotic G2 cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T11:14:22Z + +[Term] +id: GO:0072460 +name: detection of stimulus involved in meiotic recombination checkpoint +namespace: biological_process +def: "The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint." [GOC:mah] +synonym: "meiotic recombination checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "meiotic recombination checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in meiotic recombination checkpoint" RELATED [GOC:mah] +is_a: GO:0072409 ! detection of stimulus involved in meiotic cell cycle checkpoint +intersection_of: GO:0072409 ! detection of stimulus involved in meiotic cell cycle checkpoint +intersection_of: part_of GO:0051598 ! meiotic recombination checkpoint +relationship: part_of GO:0051598 ! meiotic recombination checkpoint +created_by: mah +creation_date: 2010-12-09T11:36:42Z + +[Term] +id: GO:0072461 +name: response to meiotic recombination checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "meiotic recombination checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in meiotic recombination checkpoint" EXACT [GOC:mah] +is_a: GO:0072410 ! response to meiotic cell cycle checkpoint signaling +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0051598 ! meiotic recombination checkpoint +created_by: mah +creation_date: 2010-12-09T11:37:01Z + +[Term] +id: GO:0072462 +name: signal transduction involved in meiotic recombination checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a meiotic recombination checkpoint." [GOC:mah] +is_a: GO:0072411 ! signal transduction involved in meiotic cell cycle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0051598 ! meiotic recombination checkpoint +relationship: part_of GO:0051598 ! meiotic recombination checkpoint +created_by: mah +creation_date: 2010-12-09T11:37:17Z + +[Term] +id: GO:0072463 +name: detection of stimulus involved in meiotic spindle assembly checkpoint +namespace: biological_process +def: "The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint." [GOC:mah] +synonym: "meiotic spindle assembly checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "meiotic spindle assembly checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in meiotic spindle assembly checkpoint" RELATED [GOC:mah] +is_a: GO:0072409 ! detection of stimulus involved in meiotic cell cycle checkpoint +is_a: GO:0072484 ! detection of stimulus involved in spindle assembly checkpoint +is_a: GO:1902397 ! detection of stimulus involved in meiotic spindle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0033316 ! meiotic spindle assembly checkpoint +relationship: part_of GO:0033316 ! meiotic spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T11:37:41Z + +[Term] +id: GO:0072464 +name: response to meiotic spindle assembly checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "meiotic spindle assembly checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in meiotic spindle assembly checkpoint" EXACT [GOC:mah] +is_a: GO:0072410 ! response to meiotic cell cycle checkpoint signaling +is_a: GO:0072485 ! response to spindle assembly checkpoint signaling +created_by: mah +creation_date: 2010-12-09T11:37:48Z + +[Term] +id: GO:0072465 +name: signal transduction involved in meiotic spindle assembly checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a meiotic spindle assembly checkpoint." [GOC:mtg_cell_cycle] +is_a: GO:0072486 ! signal transduction involved in spindle assembly checkpoint +is_a: GO:1902398 ! intracellular signal transduction involved in meiotic spindle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0033316 ! meiotic spindle assembly checkpoint +relationship: part_of GO:0033316 ! meiotic spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T11:37:54Z + +[Term] +id: GO:0072466 +name: obsolete detection of stimulus involved in cell shape checkpoint +namespace: biological_process +def: "OBSOLETE. The series of events in which information about aspects of cell polarity control is received and converted into a molecular signal, contributing to a cell shape checkpoint." [GOC:mah, GOC:mtg_cell_cycle] +comment: This term was made obsolete because it was ambiguous. +synonym: "cell shape checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "cell shape checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in cell shape checkpoint" RELATED [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-12-09T11:43:58Z + +[Term] +id: GO:0072467 +name: obsolete response to cell shape checkpoint signaling +namespace: biological_process +def: "OBSOLETE. A process that occurs in response to signals generated as a result of cell shape checkpoint signaling." [GOC:mtg_cell_cycle] +comment: This term was made obsolete because it was ambiguous. +synonym: "cell shape checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in cell shape checkpoint" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2010-12-09T11:44:11Z + +[Term] +id: GO:0072468 +name: obsolete signal transduction involved in cell shape checkpoint +namespace: biological_process +def: "OBSOLETE. A signal transduction process that contributes to a cell shape checkpoint." [GOC:mah] +comment: This term was made obsolete because it was ambiguous. +is_obsolete: true +created_by: mah +creation_date: 2010-12-09T11:45:12Z + +[Term] +id: GO:0072469 +name: detection of stimulus involved in cell size control checkpoint +namespace: biological_process +def: "The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint." [GOC:mtg_cell_cycle] +synonym: "cell size control checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "cell size control checkpoint sensor process" RELATED [GOC:mah] +synonym: "detection of stimulus involved in mitotic cell cycle cell size control checkpoint" EXACT [GOC:mah] +synonym: "sensing involved in cell size control checkpoint" RELATED [GOC:mah] +is_a: GO:0072412 ! detection of stimulus involved in mitotic cell cycle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0031567 ! mitotic cell size control checkpoint +relationship: part_of GO:0031567 ! mitotic cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T11:46:08Z + +[Term] +id: GO:0072470 +name: response to cell size control checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of cell size control checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "cell size control checkpoint effector process" EXACT [GOC:mah] +synonym: "response to mitotic cell cycle cell size control checkpoint signaling" EXACT [GOC:mah] +synonym: "response to signal involved in cell size control checkpoint" EXACT [GOC:mah] +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +created_by: mah +creation_date: 2010-12-09T11:46:13Z + +[Term] +id: GO:0072471 +name: signal transduction involved in cell size control checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a cell size control checkpoint during mitosis." [GOC:mtg_cell_cycle] +is_a: GO:0072413 ! signal transduction involved in mitotic cell cycle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031567 ! mitotic cell size control checkpoint +relationship: part_of GO:0031567 ! mitotic cell size control checkpoint +created_by: mah +creation_date: 2010-12-09T11:46:18Z + +[Term] +id: GO:0072475 +name: detection of stimulus involved in mitotic spindle checkpoint +namespace: biological_process +def: "The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in mitotic cell cycle spindle checkpoint" EXACT [] +synonym: "mitotic cell cycle spindle checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle spindle checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle spindle checkpoint" RELATED [GOC:mah] +is_a: GO:0072412 ! detection of stimulus involved in mitotic cell cycle checkpoint +is_a: GO:0072415 ! detection of stimulus involved in spindle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0071174 ! mitotic spindle checkpoint +relationship: part_of GO:0071174 ! mitotic spindle checkpoint +created_by: mah +creation_date: 2010-12-09T11:49:55Z + +[Term] +id: GO:0072476 +name: response to mitotic spindle checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle spindle checkpoint effector process" EXACT [GOC:mah] +synonym: "response to mitotic cell cycle spindle checkpoint signaling" EXACT [] +synonym: "response to signal involved in mitotic cell cycle spindle checkpoint" EXACT [GOC:mah] +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +is_a: GO:0072417 ! response to spindle checkpoint signaling +created_by: mah +creation_date: 2010-12-09T11:50:09Z + +[Term] +id: GO:0072477 +name: signal transduction involved in mitotic spindle checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a mitotic cell cycle spindle checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in mitotic cell cycle spindle checkpoint" EXACT [] +is_a: GO:0072413 ! signal transduction involved in mitotic cell cycle checkpoint +is_a: GO:0072416 ! signal transduction involved in spindle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0071174 ! mitotic spindle checkpoint +relationship: part_of GO:0071174 ! mitotic spindle checkpoint +created_by: mah +creation_date: 2010-12-09T11:50:16Z + +[Term] +id: GO:0072478 +name: detection of stimulus involved in mitotic spindle assembly checkpoint +namespace: biological_process +alt_id: GO:1902419 +def: "The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in Dma1-dependent checkpoint" NARROW [] +synonym: "detection of stimulus involved in mitotic cell cycle spindle assembly checkpoint" EXACT [] +synonym: "detection of stimulus involved in SAC-independent checkpoint" EXACT [GOC:TermGenie] +synonym: "mitotic cell cycle spindle assembly checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle spindle assembly checkpoint sensor process" RELATED [GOC:mah] +synonym: "perception of stimulus involved in DMA1-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "perception of stimulus involved in SAC-independent checkpoint" RELATED [GOC:TermGenie] +synonym: "sensing involved in mitotic cell cycle spindle assembly checkpoint" RELATED [GOC:mah] +synonym: "stimulus detection involved in DMA1-dependent checkpoint" NARROW [GOC:TermGenie] +synonym: "stimulus detection involved in SAC-independent checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in DMA1-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus sensing involved in SAC-independent checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072475 ! detection of stimulus involved in mitotic spindle checkpoint +is_a: GO:0072484 ! detection of stimulus involved in spindle assembly checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0007094 ! mitotic spindle assembly checkpoint +relationship: part_of GO:0007094 ! mitotic spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T12:11:18Z + +[Term] +id: GO:0072479 +name: response to mitotic cell cycle spindle assembly checkpoint signaling +namespace: biological_process +alt_id: GO:0044811 +def: "A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle spindle assembly checkpoint effector process" EXACT [GOC:mah] +synonym: "response to Dma1-dependent checkpoint signaling" NARROW [] +synonym: "response to Dma1-dependent checkpoint signalling" NARROW [] +synonym: "response to signal involved in mitotic cell cycle spindle assembly checkpoint" EXACT [GOC:mah] +is_a: GO:0072476 ! response to mitotic spindle checkpoint signaling +is_a: GO:0072485 ! response to spindle assembly checkpoint signaling +created_by: mah +creation_date: 2010-12-09T12:11:31Z + +[Term] +id: GO:0072480 +name: signal transduction involved in mitotic spindle assembly checkpoint +namespace: biological_process +alt_id: GO:1902420 +def: "A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint." [GOC:mtg_cell_cycle] +synonym: "signal transduction involved in Dma1-dependent checkpoint" NARROW [] +synonym: "signal transduction involved in mitotic cell cycle spindle assembly checkpoint" EXACT [] +synonym: "signal transduction involved in SAC-independent checkpoint" NARROW [GOC:TermGenie] +synonym: "signaling cascade involved in Dma1-dependent checkpoint" NARROW [GOC:TermGenie] +synonym: "signaling cascade involved in SAC-independent checkpoint" NARROW [GOC:TermGenie] +synonym: "signaling pathway involved in Dma1-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "signaling pathway involved in SAC-independent checkpoint" RELATED [GOC:TermGenie] +synonym: "signalling cascade involved in Dma1-dependent checkpoint" NARROW [GOC:TermGenie] +synonym: "signalling cascade involved in SAC-independent checkpoint" NARROW [GOC:TermGenie] +synonym: "signalling pathway involved in Dma1-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "signalling pathway involved in SAC-independent checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072477 ! signal transduction involved in mitotic spindle checkpoint +is_a: GO:0072486 ! signal transduction involved in spindle assembly checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0007094 ! mitotic spindle assembly checkpoint +relationship: part_of GO:0007094 ! mitotic spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T12:11:42Z + +[Term] +id: GO:0072481 +name: detection of stimulus involved in mitotic spindle orientation checkpoint +namespace: biological_process +def: "The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint." [GOC:mtg_cell_cycle] +synonym: "detection of stimulus involved in mitotic cell cycle spindle orientation checkpoint" EXACT [] +synonym: "mitotic cell cycle spindle orientation checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "mitotic cell cycle spindle orientation checkpoint sensor process" RELATED [GOC:mah] +synonym: "sensing involved in mitotic cell cycle spindle orientation checkpoint" RELATED [GOC:mah] +is_a: GO:0072475 ! detection of stimulus involved in mitotic spindle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0031578 ! mitotic spindle orientation checkpoint +relationship: part_of GO:0031578 ! mitotic spindle orientation checkpoint +created_by: mah +creation_date: 2010-12-09T12:11:52Z + +[Term] +id: GO:0072482 +name: response to mitotic cell cycle spindle orientation checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "mitotic cell cycle spindle orientation checkpoint effector process" EXACT [GOC:mah] +synonym: "response to signal involved in mitotic cell cycle spindle orientation checkpoint" EXACT [GOC:mah] +is_a: GO:0072476 ! response to mitotic spindle checkpoint signaling +created_by: mah +creation_date: 2010-12-09T12:11:56Z + +[Term] +id: GO:0072483 +name: signal transduction involved in mitotic cell cycle spindle orientation checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a mitotic cell cycle spindle orientation checkpoint." [GOC:mtg_cell_cycle] +is_a: GO:0072477 ! signal transduction involved in mitotic spindle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0031578 ! mitotic spindle orientation checkpoint +relationship: part_of GO:0031578 ! mitotic spindle orientation checkpoint +created_by: mah +creation_date: 2010-12-09T12:12:00Z + +[Term] +id: GO:0072484 +name: detection of stimulus involved in spindle assembly checkpoint +namespace: biological_process +def: "The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint." [GOC:mah] +synonym: "sensing involved in spindle assembly checkpoint" RELATED [GOC:mah] +synonym: "spindle assembly checkpoint sensor mechanism" RELATED [GOC:mah] +synonym: "spindle assembly checkpoint sensor process" RELATED [GOC:mah] +is_a: GO:0072415 ! detection of stimulus involved in spindle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0071173 ! spindle assembly checkpoint +relationship: part_of GO:0071173 ! spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T12:19:16Z + +[Term] +id: GO:0072485 +name: response to spindle assembly checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling." [GOC:mtg_cell_cycle] +synonym: "response to signal involved in spindle assembly checkpoint" EXACT [GOC:mah] +synonym: "spindle assembly checkpoint effector process" EXACT [GOC:mah] +is_a: GO:0072417 ! response to spindle checkpoint signaling +created_by: mah +creation_date: 2010-12-09T12:19:35Z + +[Term] +id: GO:0072486 +name: signal transduction involved in spindle assembly checkpoint +namespace: biological_process +def: "A signal transduction process that contributes to a spindle assembly checkpoint." [GOC:mtg_cell_cycle] +is_a: GO:0072416 ! signal transduction involved in spindle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0071173 ! spindle assembly checkpoint +relationship: part_of GO:0071173 ! spindle assembly checkpoint +created_by: mah +creation_date: 2010-12-09T12:19:51Z + +[Term] +id: GO:0072487 +name: MSL complex +namespace: cellular_component +def: "A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3." [PMID:16227571, PMID:20018852] +is_a: GO:1902562 ! H4 histone acetyltransferase complex +created_by: mah +creation_date: 2010-12-10T10:15:11Z + +[Term] +id: GO:0072488 +name: ammonium transmembrane transport +namespace: biological_process +def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "ammonium membrane transport" EXACT [] +is_a: GO:0015696 ! ammonium transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mah +creation_date: 2010-12-10T10:29:57Z + +[Term] +id: GO:0072489 +name: methylammonium transmembrane transport +namespace: biological_process +def: "The process in which methylammonium is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "methylammonium membrane transport" EXACT [] +is_a: GO:0015843 ! methylammonium transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: mah +creation_date: 2010-12-10T10:36:33Z + +[Term] +id: GO:0072490 +name: toluene-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives." [GOC:mah] +synonym: "toluene and derivative metabolic process" EXACT [GOC:mah] +synonym: "toluene-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: mah +creation_date: 2010-12-14T03:46:52Z + +[Term] +id: GO:0072491 +name: toluene-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives." [GOC:mah] +synonym: "toluene and derivative catabolic process" EXACT [GOC:mah] +synonym: "toluene-containing compound breakdown" EXACT [GOC:mah] +synonym: "toluene-containing compound catabolism" EXACT [GOC:mah] +synonym: "toluene-containing compound degradation" EXACT [GOC:mah] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0072490 ! toluene-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: mah +creation_date: 2010-12-14T03:51:03Z + +[Term] +id: GO:0072492 +name: host cell mitochondrial intermembrane space +namespace: cellular_component +def: "The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope." [GOC:ecd] +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0044190 ! host cell mitochondrial envelope +created_by: mah +creation_date: 2010-12-15T11:44:02Z + +[Term] +id: GO:0072493 +name: host cell endosome lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the host cell endosome." [GOC:ecd] +synonym: "host endosome lumen" EXACT [GOC:mah] +is_a: GO:0033655 ! host cell cytoplasm part +relationship: part_of GO:0044174 ! host cell endosome +created_by: mah +creation_date: 2010-12-15T11:45:53Z + +[Term] +id: GO:0072494 +name: host multivesicular body +namespace: cellular_component +def: "A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm." [GOC:rph] +synonym: "host cell multivesicular body" EXACT [GOC:mah] +is_a: GO:0044184 ! host cell late endosome +created_by: mah +creation_date: 2010-12-15T11:48:39Z + +[Term] +id: GO:0072495 +name: host cell Cajal body +namespace: cellular_component +def: "A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction." [GOC:rph] +synonym: "coiled body of host" EXACT [GOC:rph] +synonym: "host cell coiled body" EXACT [GOC:mah] +is_a: GO:0044094 ! host cell nuclear part +relationship: part_of GO:0044095 ! host cell nucleoplasm +created_by: mah +creation_date: 2010-12-15T11:51:12Z + +[Term] +id: GO:0072496 +name: Pup transferase activity +namespace: molecular_function +def: "Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages." [GOC:sp] +synonym: "Pup conjugating enzyme activity" NARROW [GOC:mah] +is_a: GO:0019787 ! ubiquitin-like protein transferase activity +created_by: mah +creation_date: 2010-12-15T11:58:13Z + +[Term] +id: GO:0072497 +name: mesenchymal stem cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [CL:0002452, GOC:BHF] +is_a: GO:0048863 ! stem cell differentiation +created_by: mah +creation_date: 2010-12-15T12:59:30Z + +[Term] +id: GO:0072498 +name: embryonic skeletal joint development +namespace: biological_process +def: "The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure." [GOC:BHF, GOC:vk] +is_a: GO:0048706 ! embryonic skeletal system development +created_by: mah +creation_date: 2010-12-15T04:14:42Z + +[Term] +id: GO:0072499 +name: photoreceptor cell axon guidance +namespace: biological_process +def: "The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues." [GOC:sart, PMID:20826677] +synonym: "photoreceptor cell axon pathfinding" EXACT [GOC:mah] +is_a: GO:0007411 ! axon guidance +created_by: mah +creation_date: 2010-12-15T05:34:10Z + +[Term] +id: GO:0072500 +name: obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor +namespace: biological_process +def: "OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:mah] +comment: This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand. +synonym: "negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor" EXACT [] +is_obsolete: true +consider: GO:0000122 +consider: GO:0004879 +consider: GO:0030374 +consider: GO:0030522 +created_by: mah +creation_date: 2010-12-16T11:47:39Z + +[Term] +id: GO:0072501 +name: cellular divalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell." [GOC:mah] +comment: Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular trivalent inorganic anion homeostasis' ; GO:0072502'). +is_a: GO:0030002 ! cellular anion homeostasis +is_a: GO:0072505 ! divalent inorganic anion homeostasis +created_by: mah +creation_date: 2010-12-16T12:53:05Z + +[Term] +id: GO:0072502 +name: cellular trivalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell." [GOC:mah] +comment: Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular divalent inorganic anion homeostasis' ; GO:0072501'). +is_a: GO:0030002 ! cellular anion homeostasis +is_a: GO:0072506 ! trivalent inorganic anion homeostasis +created_by: mah +creation_date: 2010-12-16T12:53:42Z + +[Term] +id: GO:0072503 +name: cellular divalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell." [GOC:mah] +comment: Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular trivalent inorganic cation homeostasis' ; GO:0072504'). +is_a: GO:0030003 ! cellular cation homeostasis +is_a: GO:0072507 ! divalent inorganic cation homeostasis +created_by: mah +creation_date: 2010-12-16T01:25:40Z + +[Term] +id: GO:0072504 +name: cellular trivalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell." [GOC:mah] +comment: Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular divalent inorganic cation homeostasis' ; GO:0072503'). +is_a: GO:0030003 ! cellular cation homeostasis +is_a: GO:0072508 ! trivalent inorganic cation homeostasis +created_by: mah +creation_date: 2010-12-16T01:26:43Z + +[Term] +id: GO:0072505 +name: divalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell." [GOC:mah] +comment: Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'trivalent inorganic anion homeostasis' ; GO:0072506'). +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis +created_by: mah +creation_date: 2010-12-16T01:39:00Z + +[Term] +id: GO:0072506 +name: trivalent inorganic anion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell." [GOC:mah] +comment: Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'divalent inorganic anion homeostasis' ; GO:0072505'). +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis +created_by: mah +creation_date: 2010-12-16T01:39:39Z + +[Term] +id: GO:0072507 +name: divalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell." [GOC:mah] +comment: Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'trivalent inorganic cation homeostasis' ; GO:0072508'). +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis +created_by: mah +creation_date: 2010-12-16T03:22:48Z + +[Term] +id: GO:0072508 +name: trivalent inorganic cation homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell." [GOC:mah] +comment: Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'divalent inorganic cation homeostasis' ; GO:0072507'). +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0098771 ! inorganic ion homeostasis +created_by: mah +creation_date: 2010-12-16T03:26:40Z + +[Term] +id: GO:0072509 +name: divalent inorganic cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of inorganic cations with a valency of two from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:mah] +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity +relationship: part_of GO:0072511 ! divalent inorganic cation transport +created_by: mah +creation_date: 2010-12-16T04:01:36Z + +[Term] +id: GO:0072510 +name: trivalent inorganic cation transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of inorganic cations with a valency of three from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:mah] +is_a: GO:0022890 ! inorganic cation transmembrane transporter activity +relationship: part_of GO:0072512 ! trivalent inorganic cation transport +created_by: mah +creation_date: 2010-12-16T04:03:00Z + +[Term] +id: GO:0072511 +name: divalent inorganic cation transport +namespace: biological_process +def: "The directed movement of inorganic cations with a valency of two into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage." [GOC:mah] +is_a: GO:0006812 ! cation transport +created_by: mah +creation_date: 2010-12-16T04:11:02Z + +[Term] +id: GO:0072512 +name: trivalent inorganic cation transport +namespace: biological_process +def: "The directed movement of inorganic cations with a valency of three into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage." [GOC:mah] +is_a: GO:0006812 ! cation transport +created_by: mah +creation_date: 2010-12-16T04:12:40Z + +[Term] +id: GO:0072513 +name: positive regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)." [GOC:BHF, GOC:mah, GOC:rl] +synonym: "negative regulation of second heart field cardioblast proliferation" EXACT [GOC:mah] +is_a: GO:0003266 ! regulation of secondary heart field cardioblast proliferation +is_a: GO:0008284 ! positive regulation of cell population proliferation +created_by: mah +creation_date: 2010-12-17T10:16:43Z + +[Term] +id: GO:0072514 +name: trehalose transport in response to water deprivation +namespace: biological_process +def: "The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water." [GOC:mah] +is_a: GO:0015771 ! trehalose transport +relationship: part_of GO:0042631 ! cellular response to water deprivation +created_by: mah +creation_date: 2010-12-21T11:26:14Z + +[Term] +id: GO:0072515 +name: trehalose transport in response to desiccation +namespace: biological_process +def: "The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water." [GOC:mah] +is_a: GO:0072514 ! trehalose transport in response to water deprivation +relationship: part_of GO:0071465 ! cellular response to desiccation +created_by: mah +creation_date: 2010-12-21T11:30:31Z + +[Term] +id: GO:0072516 +name: viral assembly compartment +namespace: cellular_component +def: "A membrane-bounded compartment that forms in the cytoplasm of virus-infected cells, in which virus assembly takes place." [GOC:BHF, PMID:20374631] +synonym: "viral assembly site" RELATED [GOC:BHF] +synonym: "virion assembly compartment" EXACT [GOC:mah] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2010-12-21T03:08:42Z + +[Term] +id: GO:0072517 +name: host cell viral assembly compartment +namespace: cellular_component +def: "A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place." [GOC:BHF, PMID:20374631] +synonym: "host cell viral assembly site" RELATED [GOC:BHF] +synonym: "host cell virion assembly compartment" EXACT [GOC:mah] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0039714 ! cytoplasmic viral factory +created_by: mah +creation_date: 2010-12-21T03:14:06Z + +[Term] +id: GO:0072518 +name: Rho-dependent protein serine/threonine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires binding of the GTPase Rho." [GOC:ecd, PMID:12778124, PMID:20230755] +synonym: "Rho-associated protein kinase activity" EXACT [GOC:ecd] +synonym: "ROCK kinase activity" EXACT [GOC:ecd] +is_a: GO:0004674 ! protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-12-22T11:07:29Z + +[Term] +id: GO:0072520 +name: seminiferous tubule development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343] +is_a: GO:0035295 ! tube development +is_a: GO:0048608 ! reproductive structure development +relationship: part_of GO:0008584 ! male gonad development +created_by: mah +creation_date: 2011-01-04T12:50:36Z + +[Term] +id: GO:0072521 +name: purine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof." [GOC:mah] +synonym: "purine and derivative metabolic process" EXACT [] +synonym: "purine-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: mah +creation_date: 2011-01-04T03:03:59Z + +[Term] +id: GO:0072522 +name: purine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof." [GOC:mah] +synonym: "purine and derivative biosynthetic process" EXACT [] +synonym: "purine-containing compound anabolism" EXACT [GOC:mah] +synonym: "purine-containing compound biosynthesis" EXACT [GOC:mah] +synonym: "purine-containing compound formation" EXACT [GOC:mah] +synonym: "purine-containing compound synthesis" EXACT [GOC:mah] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0072521 ! purine-containing compound metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: mah +creation_date: 2011-01-04T03:15:29Z + +[Term] +id: GO:0072523 +name: purine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof." [GOC:mah] +synonym: "purine and derivative catabolic process" EXACT [] +synonym: "purine-containing compound breakdown" EXACT [GOC:mah] +synonym: "purine-containing compound catabolism" EXACT [GOC:mah] +synonym: "purine-containing compound degradation" EXACT [GOC:mah] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072521 ! purine-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: mah +creation_date: 2011-01-04T03:17:20Z + +[Term] +id: GO:0072524 +name: pyridine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof." [GOC:mah] +synonym: "pyridine and derivative metabolic process" EXACT [] +synonym: "pyridine-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: mah +creation_date: 2011-01-04T03:21:47Z + +[Term] +id: GO:0072525 +name: pyridine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof." [GOC:mah] +synonym: "pyridine and derivative biosynthetic process" EXACT [] +synonym: "pyridine-containing compound anabolism" EXACT [GOC:mah] +synonym: "pyridine-containing compound biosynthesis" EXACT [GOC:mah] +synonym: "pyridine-containing compound formation" EXACT [GOC:mah] +synonym: "pyridine-containing compound synthesis" EXACT [GOC:mah] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: mah +creation_date: 2011-01-04T03:23:01Z + +[Term] +id: GO:0072526 +name: pyridine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof." [GOC:mah] +synonym: "pyridine and derivative catabolic process" EXACT [] +synonym: "pyridine-containing compound breakdown" EXACT [GOC:mah] +synonym: "pyridine-containing compound catabolism" EXACT [GOC:mah] +synonym: "pyridine-containing compound degradation" EXACT [GOC:mah] +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: mah +creation_date: 2011-01-04T03:23:14Z + +[Term] +id: GO:0072527 +name: pyrimidine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof." [GOC:mah] +synonym: "pyrimidine and derivative metabolic process" EXACT [] +synonym: "pyrimidine-containing compound metabolism" EXACT [GOC:mah] +is_a: GO:0034641 ! cellular nitrogen compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: mah +creation_date: 2011-01-04T03:27:19Z + +[Term] +id: GO:0072528 +name: pyrimidine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof." [GOC:mah] +synonym: "pyrimidine and derivative biosynthetic process" EXACT [] +synonym: "pyrimidine-containing compound anabolism" EXACT [GOC:mah] +synonym: "pyrimidine-containing compound biosynthesis" EXACT [GOC:mah] +synonym: "pyrimidine-containing compound formation" EXACT [GOC:mah] +synonym: "pyrimidine-containing compound synthesis" EXACT [GOC:mah] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: mah +creation_date: 2011-01-04T03:27:36Z + +[Term] +id: GO:0072529 +name: pyrimidine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof." [GOC:mah] +synonym: "pyrimidine and derivative catabolic process" EXACT [] +synonym: "pyrimidine-containing compound breakdown" EXACT [GOC:mah] +synonym: "pyrimidine-containing compound catabolism" EXACT [GOC:mah] +synonym: "pyrimidine-containing compound degradation" EXACT [GOC:mah] +is_a: GO:0044270 ! cellular nitrogen compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: mah +creation_date: 2011-01-04T03:27:51Z + +[Term] +id: GO:0072530 +name: purine-containing compound transmembrane transport +namespace: biological_process +def: "The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "purine-containing compound membrane transport" EXACT [] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: mah +creation_date: 2011-01-05T01:45:14Z + +[Term] +id: GO:0072531 +name: pyrimidine-containing compound transmembrane transport +namespace: biological_process +def: "The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "pyrimidine-containing compound membrane transport" EXACT [] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: mah +creation_date: 2011-01-05T01:47:22Z + +[Term] +id: GO:0072532 +name: tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives." [GOC:kad, PMID:19779199] +comment: Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-triferuloyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tri-(hydroxyferuloyl)-spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11262 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11262) and the KEGG reaction R08986 (http://www.genome.jp/dbget-bin/www_bget?rn:R08986). +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: mah +creation_date: 2011-01-12T01:54:31Z + +[Term] +id: GO:0072533 +name: tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives." [GOC:kad, PMID:19779199] +comment: Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-tricoumaroyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tricaffeoyl spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11260 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11260). +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: mah +creation_date: 2011-01-12T02:03:07Z + +[Term] +id: GO:0072534 +name: perineuronal net +namespace: cellular_component +def: "A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain." [GOC:sl, PMID:18364019] +synonym: "PNN" EXACT [GOC:sl] +is_a: GO:0098966 ! perisynaptic extracellular matrix +created_by: mah +creation_date: 2011-01-14T01:37:40Z + +[Term] +id: GO:0072535 +name: tumor necrosis factor (ligand) superfamily member 11 production +namespace: biological_process +def: "The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah] +synonym: "RANKL production" EXACT [GOC:ebc, PR:000002107] +synonym: "TNFSF11 production" EXACT [GOC:mah, PR:000002107] +synonym: "tumor necrosis factor ligand superfamily member 11 production" EXACT [GOC:bf, PR:000002107] +is_a: GO:0071706 ! tumor necrosis factor superfamily cytokine production +created_by: mah +creation_date: 2011-01-14T01:42:23Z + +[Term] +id: GO:0072536 +name: interleukin-23 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits." [GOC:BHF, GOC:mah, PMID:12023369] +synonym: "IL-23 receptor complex" EXACT [GOC:mah] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: mah +creation_date: 2011-01-14T02:51:14Z + +[Term] +id: GO:0072537 +name: fibroblast activation +namespace: biological_process +def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah] +is_a: GO:0001775 ! cell activation +created_by: mah +creation_date: 2011-01-14T04:35:08Z + +[Term] +id: GO:0072538 +name: T-helper 17 type immune response +namespace: biological_process +def: "An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22." [GOC:BHF, GOC:ebc] +synonym: "Th17 immune response" EXACT [GOC:mah] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +created_by: mah +creation_date: 2011-01-17T11:13:53Z + +[Term] +id: GO:0072539 +name: T-helper 17 cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17." [CL:0000899, GOC:BHF, GOC:ebc] +comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. +synonym: "T-helper 17 cell development" RELATED [GOC:mah] +is_a: GO:0042093 ! T-helper cell differentiation +relationship: part_of GO:0072538 ! T-helper 17 type immune response +created_by: mah +creation_date: 2011-01-17T11:18:47Z + +[Term] +id: GO:0072540 +name: T-helper 17 cell lineage commitment +namespace: biological_process +def: "The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17." [CL:0000899, GOC:BHF, GOC:ebc] +synonym: "T-helper 17 cell fate commitment" EXACT [GOC:mah] +synonym: "Th17 cell lineage commitment" EXACT [CL:0000899, GOC:mah] +synonym: "Th17 fate commitment" EXACT [CL:0000899] +is_a: GO:0002295 ! T-helper cell lineage commitment +relationship: part_of GO:0072539 ! T-helper 17 cell differentiation +created_by: mah +creation_date: 2011-01-17T11:19:48Z + +[Term] +id: GO:0072541 +name: peroxynitrite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O." [GOC:rs, PMID:11001062] +comment: Note that this activity is usually associated in vivo with an NADPH-dependent disulfide reductase activity, so that catalysis of the reduction of peroxynitrite to nitrite involves the possible creation of oxygen or water, using NADPH as reduction equivalent. +synonym: "peroxynitritase activity" EXACT [GOC:rs] +is_a: GO:0051920 ! peroxiredoxin activity +created_by: mah +creation_date: 2011-01-17T11:43:37Z + +[Term] +id: GO:0072542 +name: protein phosphatase activator activity +namespace: molecular_function +alt_id: GO:0071862 +alt_id: GO:0072543 +def: "Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule." [GOC:mah] +synonym: "protein phosphatase 2 activator activity" NARROW [GOC:dph, GOC:rl] +synonym: "protein phosphatase type 1 activator activity" NARROW [] +synonym: "protein phosphatase type 2A activator activity" NARROW [] +is_a: GO:0019211 ! phosphatase activator activity +is_a: GO:0019888 ! protein phosphatase regulator activity +created_by: mah +creation_date: 2010-09-10T03:39:56Z + +[Term] +id: GO:0072544 +name: L-DOPA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid." [GOC:mah, GOC:vw] +synonym: "L-dopa binding" EXACT [CHEBI:15765] +is_a: GO:0008144 ! drug binding +is_a: GO:0016597 ! amino acid binding +is_a: GO:0072341 ! modified amino acid binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: mah +creation_date: 2011-01-19T05:40:04Z + +[Term] +id: GO:0072545 +name: tyrosine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:mah] +synonym: "Tyr binding" EXACT [GOC:mah] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: mah +creation_date: 2011-01-19T05:43:55Z + +[Term] +id: GO:0072546 +name: ER membrane protein complex +namespace: cellular_component +def: "A transmembrane protein complex located in the ER that is involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6." [GOC:dgf, GOC:krc, GOC:vw, PMID:19325107, PMID:25313861] +synonym: "EMC" EXACT [] +synonym: "endoplasmic reticulum membrane protein complex" EXACT [GOC:mah] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030176 ! integral component of endoplasmic reticulum membrane +created_by: mah +creation_date: 2011-01-19T06:16:53Z + +[Term] +id: GO:0072547 +name: tricoumaroylspermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +synonym: "tricoumaroyl spermidine meta-hydroxylase activity" EXACT [GOC:mah] +xref: MetaCyc:RXN-11260 +is_a: GO:0072533 ! tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T02:49:37Z + +[Term] +id: GO:0072548 +name: dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +is_a: GO:0072533 ! tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T02:57:22Z + +[Term] +id: GO:0072549 +name: monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +is_a: GO:0072533 ! tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T02:58:04Z + +[Term] +id: GO:0072550 +name: triferuloylspermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +synonym: "triferuloyl spermidine meta-hydroxylase activity" EXACT [GOC:mah] +xref: MetaCyc:RXN-11262 +is_a: GO:0072532 ! tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T02:58:56Z + +[Term] +id: GO:0072551 +name: diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +is_a: GO:0072532 ! tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T03:04:16Z + +[Term] +id: GO:0072552 +name: monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O." [GOC:kad, PMID:19779199] +is_a: GO:0072532 ! tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity +created_by: mah +creation_date: 2011-01-25T03:15:31Z + +[Term] +id: GO:0072553 +name: terminal button organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters." [GOC:BHF, GOC:mah] +synonym: "bouton organization" EXACT [GOC:mah] +synonym: "presynaptic bouton organization" EXACT [GOC:mah] +synonym: "synaptic bouton organization" EXACT [GOC:mah] +synonym: "terminal bouton organization" EXACT [GOC:mah] +synonym: "terminal button organisation" EXACT [GOC:mah] +is_a: GO:0099172 ! presynapse organization +created_by: mah +creation_date: 2011-01-25T04:09:35Z + +[Term] +id: GO:0072554 +name: blood vessel lumenization +namespace: biological_process +def: "The process in which a developing blood vessel forms an endothelial lumen through which blood will flow." [GOC:dsf, PMID:16799567, PMID:20926893] +is_a: GO:0061154 ! endothelial tube morphogenesis +relationship: part_of GO:0048514 ! blood vessel morphogenesis +created_by: mah +creation_date: 2011-01-25T05:19:30Z + +[Term] +id: GO:0072555 +name: 17-beta-ketosteroid reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+." [GOC:kad, PMID:17074428] +synonym: "17-beta-ketosteroid reductase (NADPH) activity" EXACT [GOC:kad] +synonym: "7beta-ketosteroid reductase activity" EXACT [GOC:kad] +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: mah +creation_date: 2011-01-27T11:36:14Z + +[Term] +id: GO:0072557 +name: IPAF inflammasome complex +namespace: cellular_component +def: "A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri." [GOC:add, GOC:BHF, GOC:vp, PMID:20303873] +is_a: GO:0061702 ! inflammasome complex +created_by: mah +creation_date: 2011-01-27T12:01:44Z + +[Term] +id: GO:0072558 +name: NLRP1 inflammasome complex +namespace: cellular_component +def: "A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential." [GOC:add, GOC:BHF, GOC:vp, PMID:20303873] +synonym: "NALP1 inflammasome complex" EXACT [] +is_a: GO:0061702 ! inflammasome complex +created_by: mah +creation_date: 2011-01-27T12:03:50Z + +[Term] +id: GO:0072559 +name: NLRP3 inflammasome complex +namespace: cellular_component +def: "A protein complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus." [GOC:add, GOC:BHF, GOC:vp, PMID:20303873] +synonym: "NALP3 inflammasome complex" EXACT [] +is_a: GO:0061702 ! inflammasome complex +created_by: mah +creation_date: 2011-01-27T12:04:30Z + +[Term] +id: GO:0072560 +name: type B pancreatic cell maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF] +comment: These processes continue to 60 DPA in Gossypium spp. +synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah] +synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah] +is_a: GO:0002071 ! glandular epithelial cell maturation +relationship: part_of GO:0003323 ! type B pancreatic cell development +created_by: mah +creation_date: 2011-01-27T01:57:14Z + +[Term] +id: GO:0072562 +name: blood microparticle +namespace: cellular_component +def: "A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids." [GOC:BHF, GOC:mah, PMID:16373184] +synonym: "cell membrane microparticle" EXACT [PMID:16373184] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005615 ! extracellular space +created_by: mah +creation_date: 2011-01-28T11:50:56Z + +[Term] +id: GO:0072563 +name: endothelial microparticle +namespace: cellular_component +def: "A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell." [GOC:BHF, GOC:mah, PMID:16373184] +is_a: GO:0072562 ! blood microparticle +created_by: mah +creation_date: 2011-01-28T01:53:25Z + +[Term] +id: GO:0072564 +name: blood microparticle formation +namespace: biological_process +def: "The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell." [GOC:BHF, GOC:mah, PMID:16373184] +synonym: "microparticle generation" EXACT [PMID:20978343] +synonym: "microparticle release" EXACT [PMID:16373184] +is_a: GO:0016043 ! cellular component organization +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +created_by: mah +creation_date: 2011-01-28T02:15:50Z + +[Term] +id: GO:0072565 +name: endothelial microparticle formation +namespace: biological_process +def: "The cellular component organization process in which microparticles bud off from an endothelial cell." [GOC:BHF, GOC:mah, PMID:16373184] +synonym: "endothelial microparticle generation" EXACT [GOC:mah, PMID:20978343] +synonym: "endothelial microparticle release" EXACT [GOC:mah, PMID:16373184] +is_a: GO:0072564 ! blood microparticle formation +created_by: mah +creation_date: 2011-01-28T02:21:58Z + +[Term] +id: GO:0072566 +name: chemokine (C-X-C motif) ligand 1 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah] +synonym: "CXCL1 production" EXACT [GOC:BHF] +synonym: "KC production" EXACT [GOC:BHF] +synonym: "keratinocyte derived chemokine production" EXACT [GOC:BHF] +synonym: "SCYB1 production" EXACT [GOC:BHF] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2011-01-31T11:31:58Z + +[Term] +id: GO:0072567 +name: chemokine (C-X-C motif) ligand 2 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah] +synonym: "CXCL2 production" EXACT [GOC:mah] +synonym: "MIP-2 production" EXACT [GOC:BHF] +synonym: "MIP2 production" EXACT [GOC:BHF] +synonym: "SCYB2 production" EXACT [GOC:BHF] +is_a: GO:0032602 ! chemokine production +created_by: mah +creation_date: 2011-01-31T11:33:40Z + +[Term] +id: GO:0072570 +name: ADP-D-ribose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment." [GOC:mah, GOC:sart, PMID:20088964] +synonym: "ADP-ribose binding" BROAD [GOC:mah] +is_a: GO:0043168 ! anion binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0097367 ! carbohydrate derivative binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mah +creation_date: 2011-01-31T02:37:30Z + +[Term] +id: GO:0072571 +name: mono-ADP-D-ribose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment." [GOC:mah, GOC:sart, PMID:20088964] +synonym: "mADPr binding" EXACT [PMID:20088964] +synonym: "mono-ADP-ribose binding" BROAD [GOC:mah] +is_a: GO:0072570 ! ADP-D-ribose binding +created_by: mah +creation_date: 2011-01-31T02:39:12Z + +[Term] +id: GO:0072572 +name: poly-ADP-D-ribose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring." [GOC:mah, GOC:sart, PMID:20088964] +synonym: "pADPr binding" EXACT [PMID:20088964] +synonym: "poly-ADP-ribose binding" BROAD [GOC:mah] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: mah +creation_date: 2011-01-31T02:49:04Z + +[Term] +id: GO:0072573 +name: tolerance induction to lipopolysaccharide +namespace: biological_process +def: "Tolerance induction directed at lipopolysaccharide antigens." [GOC:BHF, GOC:mah] +synonym: "tolerance induction to endotoxin" BROAD [GOC:add, GOC:mah] +synonym: "tolerance induction to LPS" EXACT [GOC:add, GOC:mah] +is_a: GO:0002507 ! tolerance induction +is_a: GO:0031665 ! negative regulation of lipopolysaccharide-mediated signaling pathway +relationship: part_of GO:0071222 ! cellular response to lipopolysaccharide +created_by: mah +creation_date: 2011-02-02T03:05:19Z + +[Term] +id: GO:0072574 +name: hepatocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules." [CL:0000182, GOC:BHF, GOC:mah] +is_a: GO:0072575 ! epithelial cell proliferation involved in liver morphogenesis +created_by: mah +creation_date: 2011-02-02T03:34:49Z + +[Term] +id: GO:0072575 +name: epithelial cell proliferation involved in liver morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah] +is_a: GO:0050673 ! epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0072576 ! liver morphogenesis +relationship: part_of GO:0072576 ! liver morphogenesis +created_by: mah +creation_date: 2011-02-02T03:37:50Z + +[Term] +id: GO:0072576 +name: liver morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah] +is_a: GO:0022612 ! gland morphogenesis +relationship: part_of GO:0001889 ! liver development +created_by: mah +creation_date: 2011-02-02T03:41:30Z + +[Term] +id: GO:0072577 +name: endothelial cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +synonym: "apoptosis of endothelial cells" EXACT [GOC:mah] +synonym: "endothelial cell apoptosis" NARROW [] +synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah] +synonym: "killing of endothelial cells" EXACT [GOC:mah] +synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah] +synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: mah +creation_date: 2011-02-02T03:56:24Z + +[Term] +id: GO:0072578 +name: neurotransmitter-gated ion channel clustering +namespace: biological_process +def: "The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane." [GOC:dsf, PMID:20843816] +is_a: GO:0043113 ! receptor clustering +relationship: part_of GO:0050808 ! synapse organization +created_by: mah +creation_date: 2011-02-03T01:45:48Z + +[Term] +id: GO:0072579 +name: glycine receptor clustering +namespace: biological_process +def: "The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane." [GOC:dsf, GOC:mah, GOC:pr, PMID:20843816] +is_a: GO:0072578 ! neurotransmitter-gated ion channel clustering +relationship: part_of GO:0001941 ! postsynaptic membrane organization +created_by: mah +creation_date: 2011-02-03T01:47:40Z + +[Term] +id: GO:0072580 +name: bacterial-type EF-P lysine modification +namespace: biological_process +def: "The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P)." [GOC:curators, GOC:imk, GOC:mah, PMID:20729861, PMID:22706199, RESID:AA0530, RESID:AA0531] +comment: The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34. +synonym: "EF-P modification pathway" EXACT [PMID:22706199] +is_a: GO:0018205 ! peptidyl-lysine modification +created_by: mah +creation_date: 2011-02-07T11:47:33Z + +[Term] +id: GO:0072581 +name: protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine +namespace: biological_process +def: "The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)." [GOC:jsg, GOC:mah, PMID:20729861, RESID:AA0531] +is_a: GO:0018205 ! peptidyl-lysine modification +relationship: part_of GO:0072580 ! bacterial-type EF-P lysine modification +created_by: mah +creation_date: 2011-02-07T11:51:02Z + +[Term] +id: GO:0072582 +name: 17-beta-hydroxysteroid dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+." [GOC:kad, PMID:17074428] +xref: RHEA:24616 +is_a: GO:0033764 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: mah +creation_date: 2011-02-07T01:54:21Z + +[Term] +id: GO:0072583 +name: clathrin-dependent endocytosis +namespace: biological_process +def: "An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles." [GOC:BHF, GOC:mah, PMID:18498251, PMID:8970738, PMID:9234965] +synonym: "clathrin coated pit-dependent endocytosis" EXACT [GOC:BHF] +synonym: "clathrin-dependent endocytosis" EXACT [GOC:mah] +synonym: "clathrin-mediated endocytosis" EXACT [] +synonym: "CME" EXACT [PMID:20074057] +is_a: GO:0006898 ! receptor-mediated endocytosis +created_by: mah +creation_date: 2011-02-08T03:59:18Z + +[Term] +id: GO:0072584 +name: caveolin-mediated endocytosis +namespace: biological_process +def: "An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers." [GOC:BHF, GOC:mah, PMID:17318224, PMID:18498251, PMID:8970738, PMID:9234965] +synonym: "caveolae-dependent endocytosis" EXACT [GOC:mah] +synonym: "caveolae-mediated endocytosis" EXACT [GOC:mah] +synonym: "caveolin-dependent endocytosis" EXACT [GOC:BHF] +is_a: GO:0006897 ! endocytosis +created_by: mah +creation_date: 2011-02-08T04:08:33Z + +[Term] +id: GO:0072585 +name: xanthosine nucleotidase activity +namespace: molecular_function +def: "Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine." [GOC:kad, MetaCyc:RXN0-363, PMID:21235647] +synonym: "xanthosine ribohydrolase activity" EXACT [GOC:kad] +xref: MetaCyc:RXN0-363 +is_a: GO:0008477 ! purine nucleosidase activity +created_by: mah +creation_date: 2011-02-08T04:38:31Z + +[Term] +id: GO:0072586 +name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity +namespace: molecular_function +def: "Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:mah] +is_a: GO:0060590 ! ATPase regulator activity +relationship: part_of GO:2000371 ! regulation of DNA topoisomerase (ATP-hydrolyzing) activity +relationship: regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +created_by: mah +creation_date: 2011-02-09T05:31:50Z + +[Term] +id: GO:0072587 +name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity +namespace: molecular_function +def: "Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [GOC:mah] +is_a: GO:0001671 ! ATPase activator activity +is_a: GO:0072586 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity +relationship: part_of GO:2000373 ! positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity +relationship: positively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +created_by: mah +creation_date: 2011-02-09T05:34:47Z + +[Term] +id: GO:0072588 +name: box H/ACA RNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex." [GOC:BHF, GOC:BHF_telomerase, GOC:jbu, GOC:mah, GOC:vw, PMID:17284456, PMID:20227365] +synonym: "box H/ACA snoRNP pseudouridylase complex" RELATED [GOC:mah] +synonym: "sRNP complex" NARROW [GOC:mah, PMID:17284456, PMID:20227365] +is_a: GO:0005732 ! small nucleolar ribonucleoprotein complex +created_by: mah +creation_date: 2011-02-10T01:43:37Z + +[Term] +id: GO:0072589 +name: box H/ACA scaRNP complex +namespace: cellular_component +def: "A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs." [GOC:mah, PMID:17284456, PMID:20227365] +synonym: "nucleoplasmic box H/ACA RNP pseudouridylase complex" EXACT [GOC:mah, GOC:vw, PMID:20227365] +is_a: GO:0072588 ! box H/ACA RNP complex +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0015030 ! Cajal body +created_by: mah +creation_date: 2011-02-10T02:47:17Z + +[Term] +id: GO:0072590 +name: N-acetyl-L-aspartate-L-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate." [PMID:20643647, PMID:20657015] +xref: Reactome:R-HSA-8942575 "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG" +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +created_by: mah +creation_date: 2011-02-10T03:20:41Z + +[Term] +id: GO:0072591 +name: citrate-L-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate." [PMID:20657015] +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds +created_by: mah +creation_date: 2011-02-10T03:24:26Z + +[Term] +id: GO:0072592 +name: oxygen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah] +synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] +synonym: "oxygen metabolism" EXACT [GOC:mah] +is_a: GO:0017144 ! drug metabolic process +created_by: mah +creation_date: 2011-02-11T10:46:51Z + +[Term] +id: GO:0072593 +name: reactive oxygen species metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." [GOC:mah] +synonym: "reactive oxygen species metabolism" EXACT [GOC:mah] +synonym: "ROS metabolic process" EXACT [CHEBI:26523, GOC:mah] +is_a: GO:0044237 ! cellular metabolic process +created_by: mah +creation_date: 2011-02-11T10:50:06Z + +[Term] +id: GO:0072594 +name: establishment of protein localization to organelle +namespace: biological_process +def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] +synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle +is_a: GO:0045184 ! establishment of protein localization +created_by: mah +creation_date: 2011-02-14T01:56:51Z + +[Term] +id: GO:0072595 +name: maintenance of protein localization in organelle +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] +synonym: "maintenance of protein localisation to organelle" EXACT [GOC:mah] +synonym: "maintenance of protein localization to organelle" EXACT [] +is_a: GO:0032507 ! maintenance of protein location in cell +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0043226 ! organelle +relationship: occurs_in GO:0043226 ! organelle +relationship: part_of GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:09:13Z + +[Term] +id: GO:0072596 +name: establishment of protein localization to chloroplast +namespace: biological_process +def: "The directed movement of a protein to a specific location in a chloroplast." [GOC:mah] +synonym: "establishment of protein localisation to chloroplast" EXACT [GOC:mah] +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0072598 ! protein localization to chloroplast +created_by: mah +creation_date: 2011-02-14T02:16:13Z + +[Term] +id: GO:0072597 +name: maintenance of protein location in chloroplast +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0009507 ! chloroplast +relationship: occurs_in GO:0009507 ! chloroplast +relationship: part_of GO:0072598 ! protein localization to chloroplast +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 +created_by: mah +creation_date: 2011-02-14T02:17:48Z + +[Term] +id: GO:0072598 +name: protein localization to chloroplast +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location in a chloroplast." [GOC:ecd] +synonym: "protein localisation to chloroplast" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:20:30Z + +[Term] +id: GO:0072599 +name: establishment of protein localization to endoplasmic reticulum +namespace: biological_process +def: "The directed movement of a protein to a specific location in the endoplasmic reticulum." [GOC:mah] +synonym: "establishment of protein localisation to endoplasmic reticulum" EXACT [GOC:mah] +synonym: "establishment of protein localisation to ER" EXACT [GOC:mah] +synonym: "establishment of protein localization in endoplasmic reticulum" EXACT [] +synonym: "establishment of protein localization to ER" EXACT [GOC:mah] +is_a: GO:0070972 ! protein localization to endoplasmic reticulum +is_a: GO:0072594 ! establishment of protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:23:41Z + +[Term] +id: GO:0072601 +name: interleukin-3 secretion +namespace: biological_process +def: "The regulated release of interleukin-3 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-3 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032632 ! interleukin-3 production + +[Term] +id: GO:0072602 +name: interleukin-4 secretion +namespace: biological_process +def: "The regulated release of interleukin-4 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-4 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032633 ! interleukin-4 production + +[Term] +id: GO:0072603 +name: interleukin-5 secretion +namespace: biological_process +def: "The regulated release of interleukin-5 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-5 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032634 ! interleukin-5 production + +[Term] +id: GO:0072604 +name: interleukin-6 secretion +namespace: biological_process +def: "The regulated release of interleukin-6 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-6 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032635 ! interleukin-6 production + +[Term] +id: GO:0072605 +name: interleukin-7 secretion +namespace: biological_process +def: "The regulated release of interleukin-7 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-7 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032636 ! interleukin-7 production + +[Term] +id: GO:0072606 +name: interleukin-8 secretion +namespace: biological_process +def: "The regulated release of interleukin-8 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-8 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032637 ! interleukin-8 production + +[Term] +id: GO:0072607 +name: interleukin-9 secretion +namespace: biological_process +def: "The regulated release of interleukin-9 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-9 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032638 ! interleukin-9 production + +[Term] +id: GO:0072608 +name: interleukin-10 secretion +namespace: biological_process +def: "The regulated release of interleukin-10 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-10 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032613 ! interleukin-10 production + +[Term] +id: GO:0072609 +name: interleukin-11 secretion +namespace: biological_process +def: "The regulated release of interleukin-11 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-11 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032614 ! interleukin-11 production + +[Term] +id: GO:0072610 +name: interleukin-12 secretion +namespace: biological_process +def: "The regulated release of interleukin-12 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "CLMF secretion" NARROW [GOC:BHF] +synonym: "IL-12 secretion" EXACT [GOC:BHF] +synonym: "IL12 secretion" EXACT [GOC:BHF] +synonym: "interleukin-12 complex secretion" EXACT [GOC:BHF] +synonym: "NKSF secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032615 ! interleukin-12 production + +[Term] +id: GO:0072611 +name: interleukin-13 secretion +namespace: biological_process +def: "The regulated release of interleukin-13 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-13 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032616 ! interleukin-13 production + +[Term] +id: GO:0072612 +name: interleukin-14 secretion +namespace: biological_process +def: "The regulated release of interleukin-14 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-14 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032617 ! interleukin-14 production + +[Term] +id: GO:0072613 +name: interleukin-15 secretion +namespace: biological_process +def: "The regulated release of interleukin-15 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-15 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032618 ! interleukin-15 production + +[Term] +id: GO:0072614 +name: interleukin-16 secretion +namespace: biological_process +def: "The regulated release of interleukin-16 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-16 secretion" EXACT [GOC:BHF] +synonym: "IL16 secretion" EXACT [GOC:BHF] +synonym: "LCF secretion" NARROW [GOC:BHF] +synonym: "pro-interleukin-16 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032619 ! interleukin-16 production + +[Term] +id: GO:0072615 +name: interleukin-17 secretion +namespace: biological_process +def: "The regulated release of any member of the interleukin-17 family of cytokines from a cell." [GOC:add, GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "CTLA-8 secretion" EXACT [GOC:BHF] +synonym: "Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:BHF] +synonym: "IL-17 secretion" EXACT [GOC:BHF] +synonym: "IL-17A secretion" EXACT [GOC:BHF] +synonym: "IL17A secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032620 ! interleukin-17 production + +[Term] +id: GO:0072616 +name: interleukin-18 secretion +namespace: biological_process +def: "The regulated release of interleukin-18 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IGIF secretion" EXACT [GOC:BHF] +synonym: "IL-18 secretion" EXACT [GOC:BHF] +synonym: "IL1F4 secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032621 ! interleukin-18 production + +[Term] +id: GO:0072617 +name: interleukin-19 secretion +namespace: biological_process +def: "The regulated release of interleukin-19 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-19 secretion" EXACT [GOC:BHF] +synonym: "ZMDA1 secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032622 ! interleukin-19 production + +[Term] +id: GO:0072618 +name: interleukin-20 secretion +namespace: biological_process +def: "The regulated release of interleukin-20 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-20 secretion" EXACT [GOC:BHF] +synonym: "ZCYTO10 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032624 ! interleukin-20 production + +[Term] +id: GO:0072619 +name: interleukin-21 secretion +namespace: biological_process +def: "The regulated release of interleukin-21 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-21 secretion" EXACT [GOC:BHF] +synonym: "IL21 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032625 ! interleukin-21 production + +[Term] +id: GO:0072620 +name: interleukin-22 secretion +namespace: biological_process +def: "The regulated release of interleukin-22 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-22 secretion" EXACT [GOC:BHF] +synonym: "IL22 secretion" EXACT [GOC:BHF] +synonym: "ILTIF secretion" EXACT [GOC:BHF] +synonym: "ZCYTO18 secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032626 ! interleukin-22 production + +[Term] +id: GO:0072621 +name: interleukin-23 secretion +namespace: biological_process +def: "The regulated release of interleukin-23 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-23 secretion" EXACT [GOC:BHF] +synonym: "IL23 secretion" EXACT [GOC:BHF] +synonym: "interleukin-23 complex secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032627 ! interleukin-23 production + +[Term] +id: GO:0072622 +name: interleukin-24 secretion +namespace: biological_process +def: "The regulated release of interleukin-24 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-24 secretion" EXACT [GOC:BHF] +synonym: "IL24 secretion" EXACT [GOC:BHF] +synonym: "MDA7 secretion" EXACT [GOC:BHF] +synonym: "ST16 secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032628 ! interleukin-24 production + +[Term] +id: GO:0072623 +name: interleukin-25 secretion +namespace: biological_process +def: "The regulated release of interleukin-25 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-25 secretion" EXACT [GOC:BHF] +synonym: "IL17E secretion" EXACT [GOC:BHF] +synonym: "IL25 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032629 ! interleukin-25 production + +[Term] +id: GO:0072624 +name: interleukin-26 secretion +namespace: biological_process +def: "The regulated release of interleukin-26 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "AK155 secretion" NARROW [GOC:BHF] +synonym: "IL-26 secretion" EXACT [GOC:BHF] +synonym: "IL26 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032630 ! interleukin-26 production + +[Term] +id: GO:0072625 +name: interleukin-27 secretion +namespace: biological_process +def: "The regulated release of interleukin-27 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-27 secretion" EXACT [GOC:BHF] +synonym: "IL27 secretion" EXACT [GOC:BHF] +synonym: "interleukin-27 complex secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032631 ! interleukin-27 production + +[Term] +id: GO:0072626 +name: interleukin-35 secretion +namespace: biological_process +def: "The regulated release of interleukin-35 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-35 secretion" EXACT [GOC:BHF] +synonym: "IL35 secretion" EXACT [GOC:BHF] +synonym: "interleukin-35 complex secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0070753 ! interleukin-35 production + +[Term] +id: GO:0072627 +name: interleukin-28A production +namespace: biological_process +def: "The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-28A production" EXACT [GOC:BHF] +synonym: "IL28A production" EXACT [GOC:BHF] +synonym: "interferon lambda 2 production" EXACT [GOC:BHF] +is_a: GO:0034343 ! type III interferon production + +[Term] +id: GO:0072628 +name: interleukin-28A secretion +namespace: biological_process +def: "The regulated release of interleukin-28A from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-28A secretion" EXACT [GOC:BHF] +synonym: "IL28A secretion" EXACT [GOC:BHF] +synonym: "interferon lambda 2 secretion" EXACT [GOC:BHF] +is_a: GO:0072644 ! type III interferon secretion +relationship: part_of GO:0072627 ! interleukin-28A production + +[Term] +id: GO:0072629 +name: interleukin-28B production +namespace: biological_process +def: "The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-28B production" EXACT [GOC:BHF] +synonym: "IL28B production" EXACT [GOC:BHF] +synonym: "interferon lambda 3 production" EXACT [GOC:BHF] +is_a: GO:0034343 ! type III interferon production + +[Term] +id: GO:0072630 +name: interleukin-28B secretion +namespace: biological_process +def: "The regulated release of interleukin-28B from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-28B secretion" EXACT [GOC:BHF] +synonym: "IL28B secretion" EXACT [GOC:BHF] +synonym: "interferon lambda 3 secretion" EXACT [GOC:BHF] +is_a: GO:0072644 ! type III interferon secretion +relationship: part_of GO:0072629 ! interleukin-28B production + +[Term] +id: GO:0072631 +name: interleukin-29 production +namespace: biological_process +def: "The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-29 production" EXACT [GOC:BHF] +synonym: "IL29 production" EXACT [GOC:BHF] +synonym: "interferon lambda 1 production" EXACT [GOC:BHF] +is_a: GO:0034343 ! type III interferon production + +[Term] +id: GO:0072632 +name: interleukin-29 secretion +namespace: biological_process +def: "The regulated release of interleukin-29 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-29 secretion" EXACT [GOC:BHF] +synonym: "IL29 secretion" EXACT [GOC:BHF] +synonym: "interferon lambda 1 secretion" EXACT [GOC:BHF] +is_a: GO:0072644 ! type III interferon secretion +relationship: part_of GO:0072631 ! interleukin-29 production + +[Term] +id: GO:0072633 +name: interleukin-30 production +namespace: biological_process +def: "The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-30 production" EXACT [GOC:BHF] +synonym: "interleukin-30 complex production" EXACT [GOC:BHF] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0072634 +name: interleukin-30 secretion +namespace: biological_process +def: "The regulated release of interleukin-30 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-30 secretion" EXACT [GOC:BHF] +synonym: "interleukin-30 complex secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0072633 ! interleukin-30 production + +[Term] +id: GO:0072635 +name: interleukin-31 production +namespace: biological_process +def: "The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-31 production" EXACT [GOC:BHF] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0072636 +name: interleukin-31 secretion +namespace: biological_process +def: "The regulated release of interleukin-31 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-31 secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0072635 ! interleukin-31 production + +[Term] +id: GO:0072637 +name: interleukin-32 production +namespace: biological_process +def: "The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-32 production" EXACT [GOC:BHF] +synonym: "IL32 production" EXACT [GOC:BHF] +synonym: "NK4 production" NARROW [GOC:BHF] +synonym: "TAIF production" NARROW [GOC:BHF] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0072638 +name: interleukin-32 secretion +namespace: biological_process +def: "The regulated release of interleukin-32 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "IL-32 secretion" EXACT [GOC:BHF] +synonym: "IL32 secretion" EXACT [GOC:BHF] +synonym: "NK4 secretion" NARROW [GOC:BHF] +synonym: "TAIF secretion" NARROW [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0072637 ! interleukin-32 production + +[Term] +id: GO:0072639 +name: interleukin-33 production +namespace: biological_process +def: "The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "C9orf26 production" NARROW [GOC:BHF] +synonym: "IL-33 production" EXACT [GOC:BHF] +synonym: "IL1F11 production" NARROW [GOC:BHF] +synonym: "IL33 production" EXACT [GOC:BHF] +synonym: "NF-HEV production" EXACT [GOC:BHF] +is_a: GO:0001816 ! cytokine production + +[Term] +id: GO:0072640 +name: interleukin-33 secretion +namespace: biological_process +def: "The regulated release of interleukin-33 from a cell." [GOC:BHF, GOC:mah, http://www.copewithcytokines.de/cope.cgi?key=interleukins] +synonym: "C9orf26 secretion" NARROW [GOC:BHF] +synonym: "IL-33 secretion" EXACT [GOC:BHF] +synonym: "IL1F11 secretion" NARROW [GOC:BHF] +synonym: "IL33 secretion" EXACT [GOC:BHF] +synonym: "NF-HEV secretion" EXACT [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0072639 ! interleukin-33 production + +[Term] +id: GO:0072641 +name: type I interferon secretion +namespace: biological_process +def: "The regulated release of type I interferon from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "type I IFN secretion" EXACT [GOC:mah] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032606 ! type I interferon production + +[Term] +id: GO:0072642 +name: interferon-alpha secretion +namespace: biological_process +def: "The regulated release of interferon-alpha from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-alpha secretion" EXACT [GOC:mah] +synonym: "IFNA secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0032607 ! interferon-alpha production + +[Term] +id: GO:0072643 +name: interferon-gamma secretion +namespace: biological_process +def: "The regulated release of interferon-gamma from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-gamma secretion" EXACT [GOC:mah] +synonym: "IFNG secretion" EXACT [GOC:BHF] +synonym: "type II IFN secretion" BROAD [GOC:mah] +synonym: "type II interferon secretion" BROAD [GOC:BHF] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032609 ! interferon-gamma production + +[Term] +id: GO:0072644 +name: type III interferon secretion +namespace: biological_process +def: "The regulated release of type III interferon from a cell. Interferon lambda is the only member of the type III interferon found so far." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "type III IFN secretion" EXACT [GOC:mah] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0034343 ! type III interferon production + +[Term] +id: GO:0072645 +name: interferon-delta production +namespace: biological_process +def: "The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-delta production" EXACT [GOC:mah] +synonym: "IFND production" EXACT [GOC:BHF] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0072646 +name: interferon-delta secretion +namespace: biological_process +def: "The regulated release of interferon-delta from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-delta secretion" EXACT [GOC:mah] +synonym: "IFND secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0072645 ! interferon-delta production + +[Term] +id: GO:0072647 +name: interferon-epsilon production +namespace: biological_process +def: "The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-epsilon production" EXACT [GOC:mah] +synonym: "IFNE production" EXACT [GOC:BHF] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0072648 +name: interferon-epsilon secretion +namespace: biological_process +def: "The regulated release of interferon-epsilon from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-epsilon secretion" EXACT [GOC:mah] +synonym: "IFNE secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0072647 ! interferon-epsilon production + +[Term] +id: GO:0072649 +name: interferon-kappa production +namespace: biological_process +def: "The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-kappa production" EXACT [GOC:mah] +synonym: "IFNK production" EXACT [GOC:BHF] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0072650 +name: interferon-kappa secretion +namespace: biological_process +def: "The regulated release of interferon-kappa from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-kappa secretion" EXACT [GOC:mah] +synonym: "IFNK secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0072649 ! interferon-kappa production + +[Term] +id: GO:0072651 +name: interferon-tau production +namespace: biological_process +def: "The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-tau production" EXACT [GOC:mah] +synonym: "IFNT production" EXACT [GOC:BHF] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0072652 +name: interferon-tau secretion +namespace: biological_process +def: "The regulated release of interferon-tau from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-tau secretion" EXACT [GOC:mah] +synonym: "IFNT secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0072651 ! interferon-tau production + +[Term] +id: GO:0072653 +name: interferon-omega production +namespace: biological_process +def: "The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-omega production" EXACT [GOC:mah] +synonym: "IFNW production" EXACT [GOC:BHF] +is_a: GO:0032606 ! type I interferon production + +[Term] +id: GO:0072654 +name: interferon-omega secretion +namespace: biological_process +def: "The regulated release of interferon-omega from a cell." [GOC:BHF, GOC:mah, PMID:15546383] +synonym: "IFN-omega secretion" EXACT [GOC:mah] +synonym: "IFNW secretion" EXACT [GOC:BHF] +is_a: GO:0072641 ! type I interferon secretion +relationship: part_of GO:0072653 ! interferon-omega production + +[Term] +id: GO:0072655 +name: establishment of protein localization to mitochondrion +namespace: biological_process +def: "The directed movement of a protein to the mitochondrion or a part of the mitochondrion." [GOC:mah] +synonym: "establishment of protein localisation to mitochondrion" EXACT [GOC:mah] +synonym: "establishment of protein localization in mitochondrion" EXACT [] +is_a: GO:0070585 ! protein localization to mitochondrion +is_a: GO:0072594 ! establishment of protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:28:54Z + +[Term] +id: GO:0072656 +name: maintenance of protein location in mitochondrion +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +relationship: part_of GO:0070585 ! protein localization to mitochondrion +created_by: mah +creation_date: 2011-02-14T02:30:43Z + +[Term] +id: GO:0072657 +name: protein localization to membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] +synonym: "protein localisation in membrane" EXACT [GOC:mah] +synonym: "protein localization in membrane" EXACT [] +is_a: GO:0034613 ! cellular protein localization +created_by: mah +creation_date: 2011-02-14T02:35:18Z + +[Term] +id: GO:0072658 +name: maintenance of protein location in membrane +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0032507 ! maintenance of protein location in cell +relationship: part_of GO:0072657 ! protein localization to membrane +created_by: mah +creation_date: 2011-02-14T02:39:41Z + +[Term] +id: GO:0072659 +name: protein localization to plasma membrane +namespace: biological_process +alt_id: GO:0072661 +alt_id: GO:0090002 +def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah] +subset: goslim_pombe +synonym: "protein localisation in plasma membrane" RELATED [GOC:mah] +synonym: "protein localization in plasma membrane" RELATED [] +synonym: "protein targeting to plasma membrane" RELATED [] +synonym: "protein-plasma membrane targeting" RELATED [GOC:mah] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery +created_by: tb +creation_date: 2009-07-10T10:29:23Z + +[Term] +id: GO:0072660 +name: maintenance of protein location in plasma membrane +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0072658 ! maintenance of protein location in membrane +relationship: part_of GO:0072659 ! protein localization to plasma membrane +created_by: mah +creation_date: 2011-02-14T02:46:08Z + +[Term] +id: GO:0072662 +name: protein localization to peroxisome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location in a peroxisome." [GOC:ecd] +synonym: "protein localisation to peroxisome" EXACT [GOC:mah] +is_a: GO:0007031 ! peroxisome organization +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:50:04Z + +[Term] +id: GO:0072663 +name: establishment of protein localization to peroxisome +namespace: biological_process +def: "The directed movement of a protein to a specific location in a peroxisome." [GOC:mah] +synonym: "establishment of protein localisation to peroxisome" EXACT [GOC:mah] +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0072662 ! protein localization to peroxisome +created_by: mah +creation_date: 2011-02-14T02:50:36Z + +[Term] +id: GO:0072664 +name: maintenance of protein location in peroxisome +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005777 ! peroxisome +relationship: occurs_in GO:0005777 ! peroxisome +relationship: part_of GO:0072662 ! protein localization to peroxisome +created_by: mah +creation_date: 2011-02-14T02:51:51Z + +[Term] +id: GO:0072665 +name: protein localization to vacuole +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd] +synonym: "protein localisation to vacuole" EXACT [GOC:mah] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2011-02-14T02:55:35Z + +[Term] +id: GO:0072666 +name: establishment of protein localization to vacuole +namespace: biological_process +def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah] +synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah] +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0072665 ! protein localization to vacuole +created_by: mah +creation_date: 2011-02-14T02:56:29Z + +[Term] +id: GO:0072667 +name: maintenance of protein location in vacuole +namespace: biological_process +def: "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." [GOC:mah] +is_a: GO:0072595 ! maintenance of protein localization in organelle +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0005773 ! vacuole +relationship: occurs_in GO:0005773 ! vacuole +relationship: part_of GO:0072665 ! protein localization to vacuole +created_by: mah +creation_date: 2011-02-14T02:56:57Z + +[Term] +id: GO:0072668 +name: obsolete tubulin complex biogenesis +namespace: biological_process +def: "OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled." [GOC:mah] +comment: This term was obsoleted because biogenesis should only be used for complexes where synthesis of some non-protein component is necessary for assembly. +synonym: "tubulin complex biogenesis" EXACT [] +is_obsolete: true +replaced_by: GO:0007021 +created_by: mah +creation_date: 2011-02-14T03:25:18Z + +[Term] +id: GO:0072669 +name: tRNA-splicing ligase complex +namespace: cellular_component +def: "A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester." [GOC:sp, PMID:21311021] +synonym: "tRNA splicing ligase complex" EXACT [GOC:mah] +xref: MetaCyc:ENTMULTI-CPLX +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +created_by: mah +creation_date: 2011-02-18T10:55:26Z + +[Term] +id: GO:0072670 +name: mitochondrial tRNA threonylcarbamoyladenosine modification +namespace: biological_process +def: "The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base)." [GOC:mcc, PMID:21183954] +synonym: "mitochondrial tRNA t6A modification" EXACT [GOC:mcc] +is_a: GO:0002949 ! tRNA threonylcarbamoyladenosine modification +is_a: GO:0070900 ! mitochondrial tRNA modification +created_by: mah +creation_date: 2011-02-18T11:34:35Z + +[Term] +id: GO:0072671 +name: mitochondria-associated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions." [GOC:mcc, PMID:21070972, PMID:21109188] +synonym: "MAD" EXACT [GOC:mcc] +synonym: "mitochondria-associated protein catabolic process" EXACT [] +synonym: "mitochondria-associated protein degradation" EXACT [GOC:mcc] +synonym: "mitochondrion-associated protein catabolic process" EXACT [GOC:mah] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +created_by: mah +creation_date: 2011-02-18T11:53:28Z + +[Term] +id: GO:0072672 +name: neutrophil extravasation +namespace: biological_process +def: "The migration of a neutrophil from the blood vessels into the surrounding tissue." [CL:0000775, GOC:BHF] +is_a: GO:0045123 ! cellular extravasation +is_a: GO:1990266 ! neutrophil migration +created_by: mah +creation_date: 2011-02-21T03:03:52Z + +[Term] +id: GO:0072673 +name: lamellipodium morphogenesis +namespace: biological_process +def: "A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized." [GOC:BHF, GOC:mah] +synonym: "lamellipodium organization" RELATED [GOC:mah] +is_a: GO:0097581 ! lamellipodium organization +is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis +created_by: mah +creation_date: 2011-02-21T03:11:55Z + +[Term] +id: GO:0072674 +name: multinuclear osteoclast differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." [CL:0000779, GOC:mah, PMID:12713016] +synonym: "multinuclear osteoclast formation" RELATED [GOC:BHF, GOC:mah] +synonym: "multinuclear osteoclast morphogenesis" RELATED [GOC:BHF, GOC:mah] +is_a: GO:0030316 ! osteoclast differentiation +created_by: mah +creation_date: 2011-02-22T02:10:38Z + +[Term] +id: GO:0072675 +name: osteoclast fusion +namespace: biological_process +def: "The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast." [CL:0000092, CL:0000779, GOC:BHF, GOC:mah, PMID:12713016] +is_a: GO:0000768 ! syncytium formation by plasma membrane fusion +relationship: part_of GO:0072674 ! multinuclear osteoclast differentiation +created_by: mah +creation_date: 2011-02-22T02:14:34Z + +[Term] +id: GO:0072676 +name: lymphocyte migration +namespace: biological_process +def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah] +is_a: GO:0050900 ! leukocyte migration +created_by: mah +creation_date: 2011-02-22T03:38:12Z + +[Term] +id: GO:0072677 +name: eosinophil migration +namespace: biological_process +def: "The movement of an eosinophil within or between different tissues and organs of the body." [CL:0000771, GOC:BHF, GOC:mah] +is_a: GO:0097530 ! granulocyte migration +created_by: mah +creation_date: 2011-02-22T03:39:31Z + +[Term] +id: GO:0072678 +name: T cell migration +namespace: biological_process +def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah] +synonym: "T lymphocyte migration" EXACT [CL:0000084] +synonym: "T-cell migration" EXACT [CL:0000084] +synonym: "T-lymphocyte migration" EXACT [CL:0000084] +is_a: GO:0072676 ! lymphocyte migration +created_by: mah +creation_date: 2011-02-22T03:40:40Z + +[Term] +id: GO:0072679 +name: thymocyte migration +namespace: biological_process +def: "The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development." [CL:0000893, GOC:BHF, GOC:mah] +synonym: "immature T cell migration" RELATED [CL:0000893] +synonym: "immature T lymphocyte migration" RELATED [CL:0000893] +synonym: "immature T-cell migration" RELATED [CL:0000893] +synonym: "immature T-lymphocyte migration" RELATED [CL:0000893] +synonym: "thymic lymphocyte migration" EXACT [CL:0000893] +is_a: GO:0072678 ! T cell migration +created_by: mah +creation_date: 2011-02-22T03:47:51Z + +[Term] +id: GO:0072680 +name: extracellular matrix-dependent thymocyte migration +namespace: biological_process +def: "The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin." [CL:0000893, GOC:BHF, GOC:mah, PMID:20856819] +synonym: "extracellular matrix-dependent immature T cell migration" RELATED [CL:0000893, GOC:mah] +synonym: "extracellular matrix-dependent immature T lymphocyte migration" RELATED [CL:0000893, GOC:mah] +synonym: "extracellular matrix-dependent immature T-cell migration" RELATED [CL:0000893, GOC:mah] +synonym: "extracellular matrix-dependent immature T-lymphocyte migration" RELATED [CL:0000893, GOC:mah] +synonym: "extracellular matrix-dependent thymic lymphocyte migration" EXACT [CL:0000893, GOC:mah] +is_a: GO:0006929 ! substrate-dependent cell migration +is_a: GO:0072679 ! thymocyte migration +created_by: mah +creation_date: 2011-02-22T03:49:57Z + +[Term] +id: GO:0072681 +name: fibronectin-dependent thymocyte migration +namespace: biological_process +def: "The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix." [CL:0000893, GOC:BHF, GOC:mah, PMID:20856819] +synonym: "fibronectin-dependent immature T cell migration" RELATED [CL:0000893, GOC:mah] +synonym: "fibronectin-dependent immature T lymphocyte migration" RELATED [CL:0000893, GOC:mah] +synonym: "fibronectin-dependent immature T-cell migration" RELATED [CL:0000893, GOC:mah] +synonym: "fibronectin-dependent immature T-lymphocyte migration" RELATED [CL:0000893, GOC:mah] +synonym: "fibronectin-dependent thymic lymphocyte migration" EXACT [CL:0000893, GOC:mah] +is_a: GO:0072680 ! extracellular matrix-dependent thymocyte migration +created_by: mah +creation_date: 2011-02-22T03:53:06Z + +[Term] +id: GO:0072682 +name: eosinophil extravasation +namespace: biological_process +def: "The migration of an eosinophil from the blood vessels into the surrounding tissue." [CL:0000771, GOC:BHF, GOC:mah] +is_a: GO:0045123 ! cellular extravasation +is_a: GO:0072677 ! eosinophil migration +created_by: mah +creation_date: 2011-02-22T04:02:22Z + +[Term] +id: GO:0072683 +name: T cell extravasation +namespace: biological_process +def: "The migration of a T cell from the blood vessels into the surrounding tissue." [CL:0000084, GOC:BHF, GOC:mah] +synonym: "T lymphocyte extravasation" EXACT [CL:0000084] +synonym: "T-cell extravasation" EXACT [CL:0000084] +synonym: "T-lymphocyte extravasation" EXACT [CL:0000084] +is_a: GO:0045123 ! cellular extravasation +is_a: GO:0072678 ! T cell migration +created_by: mah +creation_date: 2011-02-22T04:05:45Z + +[Term] +id: GO:0072684 +name: mitochondrial tRNA 3'-trailer cleavage, endonucleolytic +namespace: biological_process +def: "Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion." [GOC:mah] +synonym: "mitochondrial endonucleolytic tRNA 3'-end cleavage" EXACT [GOC:mah] +synonym: "mitochondrial endonucleolytic tRNA 3'-trailer cleavage" RELATED [GOC:mah] +synonym: "mitochondrial tRNA 3'-end cleavage, endonucleolytic" EXACT [GOC:mah] +is_a: GO:0000963 ! mitochondrial RNA processing +is_a: GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic +intersection_of: GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2011-02-23T01:32:52Z + +[Term] +id: GO:0072685 +name: Mre11 complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling." [GOC:mah, PMID:19211838] +synonym: "MRN complex assembly" EXACT [GOC:mah] +synonym: "MRX complex assembly" EXACT [GOC:mah] +synonym: "Rad50 complex assembly" EXACT [GOC:mah] +synonym: "RAD50-MRE11-NBN complex assembly" EXACT [CORUM:2767, GOC:mah] +synonym: "Rad50-Rad32-Nbs1 complex assembly" EXACT [GOC:mah] +synonym: "RMX complex assembly" EXACT [GOC:mah] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: mah +creation_date: 2011-05-12T02:52:06Z + +[Term] +id: GO:0072686 +name: mitotic spindle +namespace: cellular_component +def: "A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules." [GOC:mah, GOC:vw, PMID:11408572, PMID:18367542, PMID:8027178] +is_a: GO:0005819 ! spindle +created_by: mah +creation_date: 2011-07-08T05:08:16Z + +[Term] +id: GO:0072687 +name: meiotic spindle +namespace: cellular_component +def: "A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle." [GOC:mah, GOC:vw, PMID:11408572, PMID:18367542, PMID:8027178] +is_a: GO:0005819 ! spindle +created_by: mah +creation_date: 2011-07-08T05:17:08Z + +[Term] +id: GO:0072688 +name: SHREC complex localization +namespace: biological_process +def: "Any process in which a SHREC complex is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of SHREC complex localization" EXACT [GOC:mah] +synonym: "SHREC complex localisation" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization +created_by: mah +creation_date: 2011-07-20T12:51:49Z + +[Term] +id: GO:0072689 +name: MCM complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication." [GOC:mah, PMID:21813639] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: mah +creation_date: 2011-08-12T10:57:29Z + +[Term] +id: GO:0072690 +name: single-celled organism vegetative growth phase +namespace: biological_process +alt_id: GO:0062178 +def: "A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods." [GOC:mah, GOV:vw] +subset: gocheck_do_not_annotate +synonym: "stationary phase" NARROW [] +synonym: "vegetative growth of a single-celled organism" EXACT [] +is_a: GO:0044848 ! biological phase +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18275 xsd:anyURI +created_by: mah +creation_date: 2011-08-19T12:05:19Z + +[Term] +id: GO:0072691 +name: initiation of premeiotic DNA replication +namespace: biological_process +def: "A process of DNA-dependent DNA replication initiation that occurs as part of premeiotic DNA replication." [GOC:mah, PMID:10888871] +synonym: "initiation of meiotic DNA synthesis" RELATED [GOC:mah] +synonym: "initiation of premeiotic DNA synthesis" RELATED [GOC:mah] +synonym: "meiotic DNA replication initiation" RELATED [GOC:mah] +synonym: "premeiotic DNA replication initiation" EXACT [GOC:mah] +is_a: GO:1902974 ! meiotic DNA replication initiation +intersection_of: GO:0006270 ! DNA replication initiation +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: mah +creation_date: 2011-08-19T03:16:20Z + +[Term] +id: GO:0072692 +name: obsolete chromatin silencing at centromere central core +namespace: biological_process +def: "OBSOLETE. Repression of transcription of DNA at the central core of a regional centromere by altering the structure of chromatin." [GOC:mah] +comment: This term was made obsolete because the process does not exist. +synonym: "centromere central core chromatin silencing" EXACT [GOC:mah] +synonym: "chromatin silencing at centromeric central core" EXACT [GOC:vw] +synonym: "chromatin silencing at chromosome kinetochore domain" EXACT [GOC:vw] +synonym: "heterochromatic silencing at centromere central core" EXACT [GOC:mah] +is_obsolete: true +created_by: mah +creation_date: 2011-09-12T03:16:41Z + +[Term] +id: GO:0072694 +name: obsolete cell cycle arrest in response to caffeine +namespace: biological_process +def: "OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a caffeine stimulus." [GOC:mah] +comment: This term was made obsolete because it does not represent a real process. +is_obsolete: true +created_by: mah +creation_date: 2011-12-05T01:29:00Z + +[Term] +id: GO:0072695 +name: regulation of DNA recombination at telomere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA recombination within the telomere." [GOC:mah] +synonym: "regulation of telomeric recombination" EXACT [GOC:mah] +is_a: GO:0000018 ! regulation of DNA recombination +created_by: mah +creation_date: 2012-04-03T10:31:50Z + +[Term] +id: GO:0072696 +name: positive regulation of DNA recombination at telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere." [GOC:mah] +synonym: "activation of telomeric recombination at telomere" NARROW [GOC:mah] +synonym: "positive regulation of telomeric recombination" EXACT [GOC:mah] +synonym: "up regulation of telomeric recombination at telomere" EXACT [GOC:mah] +synonym: "up-regulation of telomeric recombination at telomere" EXACT [GOC:mah] +synonym: "upregulation of telomeric recombination at telomere" EXACT [GOC:mah] +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:0072695 ! regulation of DNA recombination at telomere +created_by: mah +creation_date: 2012-04-03T11:28:19Z + +[Term] +id: GO:0072697 +name: protein localization to cell cortex +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah] +synonym: "protein localisation to cell cortex" EXACT [GOC:mah] +is_a: GO:1990778 ! protein localization to cell periphery +created_by: mah +creation_date: 2012-04-11T01:16:33Z + +[Term] +id: GO:0072698 +name: protein localization to microtubule cytoskeleton +namespace: biological_process +def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah] +synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah] +is_a: GO:0044380 ! protein localization to cytoskeleton +created_by: mah +creation_date: 2012-04-11T01:19:35Z + +[Term] +id: GO:0072699 +name: protein localization to cortical microtubule cytoskeleton +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton." [GOC:mah] +synonym: "protein localisation to cortical microtubule cytoskeleton" EXACT [GOC:mah] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +created_by: mah +creation_date: 2012-04-11T01:23:36Z + +[Term] +id: GO:0072700 +name: response to bismuth +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus." [GOC:mah] +synonym: "response to bismuth ion" EXACT [] +is_a: GO:0010035 ! response to inorganic substance +created_by: mah +creation_date: 2012-04-11T02:56:35Z + +[Term] +id: GO:0072701 +name: cellular response to bismuth +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus." [GOC:mah] +synonym: "cellular response to bismuth ion" EXACT [] +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0072700 ! response to bismuth +created_by: mah +creation_date: 2012-04-11T02:56:42Z + +[Term] +id: GO:0072702 +name: response to methyl methanesulfonate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus." [GOC:mah] +synonym: "response to MMS" EXACT [CHEBI:25255, GOC:mah] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-04-11T03:04:12Z + +[Term] +id: GO:0072703 +name: cellular response to methyl methanesulfonate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus." [GOC:mah] +synonym: "cellular response to MMS" EXACT [CHEBI:25255, GOC:mah] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0072702 ! response to methyl methanesulfonate +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-04-11T03:04:18Z + +[Term] +id: GO:0072704 +name: response to mercaptoethanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus." [GOC:mah] +synonym: "response to 2-sulfanylethanol" EXACT [CHEBI:41218, GOC:mah] +is_a: GO:0097305 ! response to alcohol +created_by: mah +creation_date: 2012-04-11T03:27:02Z + +[Term] +id: GO:0072705 +name: cellular response to mercaptoethanol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus." [GOC:mah] +synonym: "cellular response to 2-sulfanylethanol" EXACT [CHEBI:41218, GOC:mah] +is_a: GO:0072704 ! response to mercaptoethanol +is_a: GO:0097306 ! cellular response to alcohol +created_by: mah +creation_date: 2012-04-11T03:27:40Z + +[Term] +id: GO:0072706 +name: response to sodium dodecyl sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus." [GOC:mah] +synonym: "response to SDS" EXACT [CHEBI:8984, GOC:mah] +is_a: GO:1902074 ! response to salt +created_by: mah +creation_date: 2012-04-11T03:35:07Z + +[Term] +id: GO:0072707 +name: cellular response to sodium dodecyl sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus." [GOC:mah] +synonym: "cellular response to SDS" EXACT [CHEBI:8984, GOC:mah] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0072706 ! response to sodium dodecyl sulfate +is_a: GO:1902075 ! cellular response to salt +created_by: mah +creation_date: 2012-04-11T03:35:15Z + +[Term] +id: GO:0072708 +name: response to sorbitol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus." [GOC:mah] +synonym: "response to glucitol" EXACT [CHEBI:30911, GOC:mah] +is_a: GO:0009743 ! response to carbohydrate +created_by: mah +creation_date: 2012-04-11T03:40:57Z + +[Term] +id: GO:0072709 +name: cellular response to sorbitol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus." [GOC:mah] +synonym: "cellular response to glucitol" EXACT [CHEBI:30911, GOC:mah] +is_a: GO:0071322 ! cellular response to carbohydrate stimulus +is_a: GO:0072708 ! response to sorbitol +created_by: mah +creation_date: 2012-04-11T03:41:03Z + +[Term] +id: GO:0072710 +name: response to hydroxyurea +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus." [GOC:mah] +synonym: "response to HU" EXACT [GOC:mah] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901698 ! response to nitrogen compound +created_by: mah +creation_date: 2012-04-11T04:15:42Z + +[Term] +id: GO:0072711 +name: cellular response to hydroxyurea +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus." [GOC:mah] +synonym: "cellular response to HU" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0072710 ! response to hydroxyurea +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: mah +creation_date: 2012-04-11T04:15:56Z + +[Term] +id: GO:0072712 +name: response to thiabendazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus." [GOC:mah] +synonym: "response to TBZ" EXACT [CHEBI:45979, GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0060992 ! response to fungicide +created_by: mah +creation_date: 2012-04-11T04:23:56Z + +[Term] +id: GO:0072713 +name: cellular response to thiabendazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus." [GOC:mah] +synonym: "cellular response to TBZ" EXACT [CHEBI:45979, GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0072712 ! response to thiabendazole +is_a: GO:0097237 ! cellular response to toxic substance +created_by: mah +creation_date: 2012-04-11T04:24:19Z + +[Term] +id: GO:0072714 +name: response to selenite ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus." [GOC:mah] +is_a: GO:0010035 ! response to inorganic substance +created_by: mah +creation_date: 2012-04-19T02:46:28Z + +[Term] +id: GO:0072715 +name: cellular response to selenite ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus." [GOC:mah] +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0072714 ! response to selenite ion +created_by: mah +creation_date: 2012-04-19T02:47:50Z + +[Term] +id: GO:0072716 +name: response to actinomycin D +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus." [GOC:mah] +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901652 ! response to peptide +created_by: mah +creation_date: 2012-04-26T02:06:40Z + +[Term] +id: GO:0072717 +name: cellular response to actinomycin D +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus." [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0072716 ! response to actinomycin D +is_a: GO:1901653 ! cellular response to peptide +created_by: mah +creation_date: 2012-04-26T02:06:55Z + +[Term] +id: GO:0072718 +name: response to cisplatin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus." [GOC:mah] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0097327 ! response to antineoplastic agent +created_by: mah +creation_date: 2012-04-30T11:31:05Z + +[Term] +id: GO:0072719 +name: cellular response to cisplatin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0072718 ! response to cisplatin +is_a: GO:0097237 ! cellular response to toxic substance +created_by: mah +creation_date: 2012-04-30T11:31:12Z + +[Term] +id: GO:0072720 +name: response to dithiothreitol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus." [GOC:mah] +synonym: "response to 1,4-dithiothreitol" EXACT [CHEBI:18320, GOC:mah] +synonym: "response to DTT" EXACT [GOC:mah] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-09T11:08:58Z + +[Term] +id: GO:0072721 +name: cellular response to dithiothreitol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus." [GOC:mah] +synonym: "cellular response to 1,4-dithiothreitol" EXACT [CHEBI:18320, GOC:mah] +synonym: "cellular response to DTT" EXACT [GOC:mah] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0072720 ! response to dithiothreitol +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-09T11:09:08Z + +[Term] +id: GO:0072722 +name: response to amitrole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus." [GOC:mah] +synonym: "response to 3-amino-1,2,4-triazole" EXACT [CHEBI:40036, GOC:mah] +is_a: GO:0009635 ! response to herbicide +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +created_by: mah +creation_date: 2012-05-31T10:51:45Z + +[Term] +id: GO:0072723 +name: cellular response to amitrole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus." [GOC:mah] +synonym: "cellular response to 3-amino-1,2,4-triazole" EXACT [CHEBI:40036, GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0072722 ! response to amitrole +is_a: GO:0097237 ! cellular response to toxic substance +created_by: mah +creation_date: 2012-05-31T10:51:52Z + +[Term] +id: GO:0072724 +name: response to 4-nitroquinoline N-oxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus." [GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-31T11:00:37Z + +[Term] +id: GO:0072725 +name: cellular response to 4-nitroquinoline N-oxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus." [GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0072724 ! response to 4-nitroquinoline N-oxide +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-31T11:00:42Z + +[Term] +id: GO:0072726 +name: response to CCCP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus." [GOC:mah] +synonym: "response to carbonyl cyanide m-chlorophenyl hydrazone" EXACT [CHEBI:3259, GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +created_by: mah +creation_date: 2012-05-31T11:16:38Z + +[Term] +id: GO:0072727 +name: cellular response to CCCP +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus." [GOC:mah] +synonym: "cellular response to carbonyl cyanide m-chlorophenyl hydrazone" EXACT [CHEBI:3259, GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0072726 ! response to CCCP +created_by: mah +creation_date: 2012-05-31T11:16:43Z + +[Term] +id: GO:0072728 +name: response to Gentian violet +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus." [GOC:mah] +synonym: "response to crystal violet" EXACT [GOC:mah] +synonym: "response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride" EXACT [CHEBI:198346, GOC:mah] +is_a: GO:0010033 ! response to organic substance +created_by: mah +creation_date: 2012-05-31T11:23:25Z + +[Term] +id: GO:0072729 +name: cellular response to Gentian violet +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus." [GOC:mah] +synonym: "cellular response to crystal violet" EXACT [GOC:mah] +synonym: "cellular response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride" EXACT [CHEBI:198346, GOC:mah] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0072728 ! response to Gentian violet +created_by: mah +creation_date: 2012-05-31T11:23:40Z + +[Term] +id: GO:0072730 +name: response to papulacandin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus." [GOC:mah] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-31T11:30:32Z + +[Term] +id: GO:0072731 +name: cellular response to papulacandin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus." [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0072730 ! response to papulacandin B +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-05-31T11:30:39Z + +[Term] +id: GO:0072732 +name: cellular response to calcium ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions." [GOC:mah] +synonym: "cellular response to calcium starvation" EXACT [GOC:mah] +is_a: GO:0009267 ! cellular response to starvation +created_by: mah +creation_date: 2012-07-06T02:42:26Z + +[Term] +id: GO:0072733 +name: response to staurosporine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus." [GOC:mah] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043279 ! response to alkaloid +created_by: mah +creation_date: 2012-07-17T10:32:28Z + +[Term] +id: GO:0072734 +name: cellular response to staurosporine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus." [GOC:mah] +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0072733 ! response to staurosporine +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072735 +name: response to tert-butyl hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus." [GOC:mah] +synonym: "response to 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:365419] +synonym: "response to t-BOOH" EXACT [GOC:mah] +is_a: GO:0033195 ! response to alkyl hydroperoxide +is_a: GO:0046677 ! response to antibiotic +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072736 +name: cellular response to tert-butyl hydroperoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus." [GOC:mah] +synonym: "cellular response to 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:365419] +synonym: "cellular response to t-BOOH" EXACT [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0071448 ! cellular response to alkyl hydroperoxide +is_a: GO:0072735 ! response to tert-butyl hydroperoxide +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072737 +name: response to diamide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus." [GOC:mah] +synonym: "response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958] +is_a: GO:1901698 ! response to nitrogen compound +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072738 +name: cellular response to diamide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus." [GOC:mah] +synonym: "cellular response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958] +is_a: GO:0072737 ! response to diamide +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072739 +name: response to anisomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus." [GOC:mah] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072740 +name: cellular response to anisomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus." [GOC:mah] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0072739 ! response to anisomycin +created_by: mah +creation_date: 2012-07-17T10:33:00Z + +[Term] +id: GO:0072741 +name: protein localization to cell division site +namespace: biological_process +def: "A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division." [GOC:mah, PMID:19756689] +synonym: "protein localisation to cell division site" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +created_by: mah +creation_date: 2012-08-16T11:51:48Z + +[Term] +id: GO:0072742 +name: SAGA complex localization to transcription regulatory region +namespace: biological_process +def: "Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene." [GOC:mah] +synonym: "SAGA complex localization to promoter" EXACT [GOC:mah] +synonym: "SAGA complex recruitment" EXACT [GOC:mah] +is_a: GO:0034629 ! cellular protein-containing complex localization +created_by: mah +creation_date: 2012-08-24T10:36:03Z + +[Term] +id: GO:0072743 +name: cellular response to erythromycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus." [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1901323 ! response to erythromycin +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-31T12:24:52Z + +[Term] +id: GO:0072744 +name: cellular response to trichodermin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901324 ! response to trichodermin +created_by: mah +creation_date: 2012-08-31T12:29:38Z + +[Term] +id: GO:0072745 +name: cellular response to antimycin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus." [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901325 ! response to antimycin A +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-31T12:31:08Z + +[Term] +id: GO:0072746 +name: cellular response to tetracycline +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901326 ! response to tetracycline +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2012-08-31T12:32:43Z + +[Term] +id: GO:0072747 +name: cellular response to chloramphenicol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901322 ! response to chloramphenicol +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-31T12:33:30Z + +[Term] +id: GO:0072748 +name: cellular response to tacrolimus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus." [GOC:mah] +synonym: "cellular response to FK506" EXACT [CHEBI:61057] +synonym: "cellular response to tacrolimus hydrate" EXACT [CHEBI:61057] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:1901327 ! response to tacrolimus +created_by: mah +creation_date: 2012-08-31T12:34:32Z + +[Term] +id: GO:0072749 +name: cellular response to cytochalasin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0036146 ! cellular response to mycotoxin +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901328 ! response to cytochalasin B +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-31T12:37:15Z + +[Term] +id: GO:0072750 +name: cellular response to leptomycin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus." [GOC:mah] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901344 ! response to leptomycin B +created_by: mah +creation_date: 2012-09-10T14:07:32Z + +[Term] +id: GO:0072751 +name: cellular response to L-thialysine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus." [GOC:mah] +synonym: "cellular response to thialysine" BROAD [GOC:mah] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1901345 ! response to L-thialysine +created_by: mah +creation_date: 2012-09-10T14:12:21Z + +[Term] +id: GO:0072752 +name: cellular response to rapamycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus." [GOC:TermGenie] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901355 ! response to rapamycin +is_a: GO:1901655 ! cellular response to ketone +created_by: mah +creation_date: 2012-09-14T11:13:34Z + +[Term] +id: GO:0072753 +name: cellular response to glutathione +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus." [GOC:mah] +is_a: GO:1901370 ! response to glutathione +is_a: GO:1901653 ! cellular response to peptide +created_by: mah +creation_date: 2012-09-25T12:27:39Z + +[Term] +id: GO:0072754 +name: cellular response to purvalanol A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus." [GOC:mah] +is_a: GO:0071415 ! cellular response to purine-containing compound +is_a: GO:1901560 ! response to purvalanol A +created_by: mah +creation_date: 2012-11-07T12:05:57Z + +[Term] +id: GO:0072755 +name: cellular response to benomyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901561 ! response to benomyl +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T12:06:58Z + +[Term] +id: GO:0072756 +name: cellular response to paraquat +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus." [GOC:mah] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901562 ! response to paraquat +created_by: mah +creation_date: 2012-11-07T12:08:59Z + +[Term] +id: GO:0072757 +name: cellular response to camptothecin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus." [GOC:mah] +synonym: "cellular response to CPT" EXACT [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071312 ! cellular response to alkaloid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901563 ! response to camptothecin +created_by: mah +creation_date: 2012-11-07T12:12:35Z + +[Term] +id: GO:0072758 +name: response to topoisomerase inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus." [GOC:mah] +is_a: GO:0042221 ! response to chemical +created_by: mah +creation_date: 2012-11-09T11:34:51Z + +[Term] +id: GO:0072759 +name: cellular response to topoisomerase inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus." [GOC:mah] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:0072758 ! response to topoisomerase inhibitor +created_by: mah +creation_date: 2012-11-09T11:38:08Z + +[Term] +id: GO:0072760 +name: cellular response to GW 7647 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus." [GOC:mah] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:1901593 ! response to GW 7647 +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-09T11:46:28Z + +[Term] +id: GO:0072761 +name: cellular response to capsazepine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus." [GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901594 ! response to capsazepine +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-09T11:47:53Z + +[Term] +id: GO:0072762 +name: cellular response to carbendazim +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901597 ! response to carbendazim +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-09T11:48:11Z + +[Term] +id: GO:0072763 +name: cellular response to hesperadin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus." [GOC:mah] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071418 ! cellular response to amine stimulus +is_a: GO:1901595 ! response to hesperadin +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-09T11:50:58Z + +[Term] +id: GO:0072764 +name: cellular response to reversine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus." [GOC:mah] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071415 ! cellular response to purine-containing compound +is_a: GO:1901596 ! response to reversine +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-09T11:52:22Z + +[Term] +id: GO:0072765 +name: centromere localization +namespace: biological_process +def: "A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location." [GOC:mah] +synonym: "establishment and maintenance of kinetochore localization" EXACT [GOC:mah] +synonym: "kinetochore localisation" EXACT [GOC:mah] +synonym: "kinetochore localization" EXACT [] +is_a: GO:0034629 ! cellular protein-containing complex localization +is_a: GO:0051640 ! organelle localization +created_by: mah +creation_date: 2012-11-21T13:30:53Z + +[Term] +id: GO:0072766 +name: centromere clustering at the mitotic interphase nuclear envelope +namespace: biological_process +def: "A cellular localization process in which kinetochores/centromeres are coupled to each other and to the nuclear periphery close to the spindle pole body/centrosome. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei." [GOC:mah, GOC:vw, PMID:21965289, PMID:23166349] +synonym: "centromere clustering at the mitotic nuclear envelope" RELATED [] +synonym: "centromere clustering at the nuclear periphery" BROAD [] +synonym: "centromere-SPB clustering" BROAD [GOC:vw, PMID:18158900] +synonym: "kinetochore clustering at SPB" BROAD [GOC:mah] +synonym: "kinetochore clustering at spindle pole body" BROAD [] +synonym: "kinetochore clustering at the old mitotic spindle pole body" EXACT [] +synonym: "kinetochore localization at spindle pole body" BROAD [GOC:pr] +synonym: "rabl configuration" RELATED [PMID:17881496] +is_a: GO:0098653 ! centromere clustering +is_a: GO:1903047 ! mitotic cell cycle process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19227 xsd:anyURI +created_by: mah +creation_date: 2012-11-21T13:32:22Z + +[Term] +id: GO:0075000 +name: response to host osmotic environment +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "response of symbiont to host osmotic environment" EXACT [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0075001 +name: adhesion of symbiont infection structure to host +namespace: biological_process +def: "The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process. +synonym: "adhesion of symbiont infection structure to host during symbiotic interaction" EXACT [] +synonym: "attachment of symbiont infection structure to host" EXACT [] +is_a: GO:0044406 ! adhesion of symbiont to host + +[Term] +id: GO:0075002 +name: adhesion of symbiont germination tube to host +namespace: biological_process +def: "The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont germination tube to host during symbiotic interaction" EXACT [] +is_a: GO:0075001 ! adhesion of symbiont infection structure to host + +[Term] +id: GO:0075003 +name: adhesion of symbiont appressorium to host +namespace: biological_process +def: "The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont appressorium to host during symbiotic interaction" EXACT [] +is_a: GO:0075001 ! adhesion of symbiont infection structure to host + +[Term] +id: GO:0075004 +name: adhesion of symbiont spore to host +namespace: biological_process +def: "The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont spore to host during symbiotic interaction" EXACT [] +is_a: GO:0044406 ! adhesion of symbiont to host + +[Term] +id: GO:0075005 +name: spore germination on or near host +namespace: biological_process +def: "The physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0009847 ! spore germination +is_a: GO:0044132 ! development of symbiont on or near host +is_a: GO:0051701 ! interaction with host + +[Term] +id: GO:0075006 +name: modulation of spore germination on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:1904359 ! regulation of spore germination +relationship: regulates GO:0075005 ! spore germination on or near host + +[Term] +id: GO:0075007 +name: positive regulation of spore germination on or near host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075006 ! modulation of spore germination on or near host +is_a: GO:1904361 ! positive regulation of spore germination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075005 ! spore germination on or near host +relationship: positively_regulates GO:0075005 ! spore germination on or near host + +[Term] +id: GO:0075008 +name: negative regulation of spore germination on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075006 ! modulation of spore germination on or near host +is_a: GO:1904360 ! negative regulation of spore germination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075005 ! spore germination on or near host +relationship: negatively_regulates GO:0075005 ! spore germination on or near host + +[Term] +id: GO:0075009 +name: germ tube formation on or near host +namespace: biological_process +def: "Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044132 ! development of symbiont on or near host +relationship: part_of GO:0075005 ! spore germination on or near host + +[Term] +id: GO:0075010 +name: modulation of germ tube formation on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075006 ! modulation of spore germination on or near host +relationship: regulates GO:0075009 ! germ tube formation on or near host + +[Term] +id: GO:0075011 +name: positive regulation of germ tube formation on or near host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075007 ! positive regulation of spore germination on or near host +is_a: GO:0075010 ! modulation of germ tube formation on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075009 ! germ tube formation on or near host +relationship: positively_regulates GO:0075009 ! germ tube formation on or near host + +[Term] +id: GO:0075012 +name: negative regulation of germ tube formation on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075008 ! negative regulation of spore germination on or near host +is_a: GO:0075010 ! modulation of germ tube formation on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075009 ! germ tube formation on or near host +relationship: negatively_regulates GO:0075009 ! germ tube formation on or near host + +[Term] +id: GO:0075013 +name: obsolete growth or development of symbiont on or near host phyllosphere +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "growth or development of symbiont on or near host phyllosphere" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075014 +name: obsolete growth or development of symbiont on or near host rhizosphere +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "growth or development of symbiont on or near host rhizosphere" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075015 +name: formation of host infection structure +namespace: biological_process +def: "The process in which a symbiont structure that serves to infect the host is formed on its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process. +synonym: "formation by symbiont of infection structure on or near host" EXACT [] +synonym: "formation of infection structure on or near host" EXACT [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0044409 ! entry into host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19014 xsd:anyURI + +[Term] +id: GO:0075016 +name: appressorium formation +namespace: biological_process +def: "The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface." [GOC:pamgo_curators] +synonym: "appressorium formation for entry into host, on or near host" EXACT [] +synonym: "appressorium formation on or near host" RELATED [] +synonym: "formation of an appressorium by symbiont on or near host" EXACT [] +is_a: GO:0044134 ! development of symbiont on or near host phyllosphere +is_a: GO:0075015 ! formation of host infection structure + +[Term] +id: GO:0075017 +name: regulation of appressorium formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont appressorium formation." [GOC:pamgo_curators] +synonym: "regulation of appressorium formation on or near host" RELATED [] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075016 ! appressorium formation +relationship: regulates GO:0075016 ! appressorium formation + +[Term] +id: GO:0075018 +name: positive regulation of appressorium formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "positive regulation of appressorium formation on or near host" RELATED [] +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075017 ! regulation of appressorium formation +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075016 ! appressorium formation +relationship: positively_regulates GO:0075016 ! appressorium formation + +[Term] +id: GO:0075019 +name: negative regulation of appressorium formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "negative regulation of appressorium formation on or near host" RELATED [] +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075017 ! regulation of appressorium formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075016 ! appressorium formation +relationship: negatively_regulates GO:0075016 ! appressorium formation + +[Term] +id: GO:0075020 +name: obsolete calcium or calmodulin-mediated activation of appressorium formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "Ca++ or calmodulin-mediated activation of appressorium formation" EXACT [] +synonym: "Ca2+ or calmodulin-mediated activation of appressorium formation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075021 +name: obsolete cAMP-mediated activation of appressorium formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "cyclic AMP mediated activation of appressorium formation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075022 +name: obsolete ethylene-mediated activation of appressorium formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0075023 +name: obsolete MAPK-mediated regulation of appressorium formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "mitogen-activated protein kinase-mediated activation of appressorium formation" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075024 +name: obsolete phospholipase C-mediated activation of appressorium formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true + +[Term] +id: GO:0075025 +name: initiation of appressorium formation +namespace: biological_process +def: "The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "appressorium initiation on or near host" EXACT [] +synonym: "initiation of appressorium by symbiont on or near host" EXACT [] +synonym: "initiation of appressorium on or near host" RELATED [] +synonym: "initiation of symbiont appressorium on or near host" EXACT [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +relationship: part_of GO:0075016 ! appressorium formation + +[Term] +id: GO:0075026 +name: regulation of appressorium initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont appressorium initiation." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "regulation of appressorium initiation on or near host" RELATED [] +synonym: "regulation of initiation of appressorium on or near host" EXACT [] +is_a: GO:0075017 ! regulation of appressorium formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075025 ! initiation of appressorium formation +relationship: regulates GO:0075025 ! initiation of appressorium formation + +[Term] +id: GO:0075027 +name: positive regulation of appressorium initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation." [GOC:pamgo_curators] +synonym: "positive regulation of appressorium initiation on or near host" RELATED [] +synonym: "positive regulation of initiation of appressorium on or near host" EXACT [] +is_a: GO:0075018 ! positive regulation of appressorium formation +is_a: GO:0075026 ! regulation of appressorium initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075025 ! initiation of appressorium formation +relationship: positively_regulates GO:0075025 ! initiation of appressorium formation + +[Term] +id: GO:0075028 +name: negative regulation of appressorium initiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation." [GOC:pamgo_curators] +synonym: "negative regulation of appressorium initiation on or near host" RELATED [] +synonym: "negative regulation of initiation of appressorium on or near host" EXACT [] +is_a: GO:0075019 ! negative regulation of appressorium formation +is_a: GO:0075026 ! regulation of appressorium initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075025 ! initiation of appressorium formation +relationship: negatively_regulates GO:0075025 ! initiation of appressorium formation + +[Term] +id: GO:0075029 +name: formation of symbiont germ tube hook structure for appressorium development +namespace: biological_process +def: "The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation." [GOC:pamgo_curators] +synonym: "formation of germ tube tip of symbiont on or near the exterior of host" EXACT [] +synonym: "formation of symbiont germ tube hook structure on or near host" RELATED [] +synonym: "symbiont germ tube hook structure formation on or near host" EXACT [] +is_a: GO:0075015 ! formation of host infection structure +relationship: part_of GO:0075025 ! initiation of appressorium formation + +[Term] +id: GO:0075030 +name: modulation of formation of symbiont germ tube hook structure for appressorium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation." [GOC:pamgo_curators] +synonym: "modulation of germ tube tip of symbiont on or near the exterior of host" EXACT [] +synonym: "modulation of symbiont germ tube hook structure formation on or near host" RELATED [] +synonym: "regulation of formation of symbiont germ tube hook structure on or near host" EXACT [] +is_a: GO:0075026 ! regulation of appressorium initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development +relationship: regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development + +[Term] +id: GO:0075031 +name: positive regulation of formation of symbiont germ tube hook structure for appressorium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation." [GOC:pamgo_curators] +synonym: "positive regulation of formation of symbiont germ tube hook structure on or near host" EXACT [] +synonym: "positive regulation of germ tube tip of symbiont on or near the exterior of host" EXACT [] +synonym: "positive regulation of symbiont germ tube hook structure formation on or near host" RELATED [] +is_a: GO:0075027 ! positive regulation of appressorium initiation +is_a: GO:0075030 ! modulation of formation of symbiont germ tube hook structure for appressorium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development +relationship: positively_regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development + +[Term] +id: GO:0075032 +name: negative regulation of formation of symbiont germ tube hook structure for appressorium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation." [GOC:pamgo_curators] +synonym: "negative regulation of formation of symbiont germ tube hook structure on or near host" EXACT [] +synonym: "negative regulation of germ tube tip of symbiont on or near the exterior of host" EXACT [] +synonym: "negative regulation of symbiont germ tube hook structure formation on or near host" RELATED [] +is_a: GO:0075028 ! negative regulation of appressorium initiation +is_a: GO:0075030 ! modulation of formation of symbiont germ tube hook structure for appressorium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development +relationship: negatively_regulates GO:0075029 ! formation of symbiont germ tube hook structure for appressorium development + +[Term] +id: GO:0075033 +name: septum formation involved in appressorium formation on or near host +namespace: biological_process +def: "The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring on or near the exterior of its host organism during appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "septum formation during appressorium formation on or near host" RELATED [GOC:tb] +is_a: GO:0044132 ! development of symbiont on or near host +relationship: part_of GO:0075016 ! appressorium formation + +[Term] +id: GO:0075034 +name: nuclear division involved in appressorium formation on or near host +namespace: biological_process +def: "The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:dph, GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "nuclear division during appressorium formation on or near host" RELATED [GOC:dph] +is_a: GO:0000280 ! nuclear division +intersection_of: GO:0000280 ! nuclear division +intersection_of: part_of GO:0075016 ! appressorium formation +relationship: part_of GO:0075016 ! appressorium formation + +[Term] +id: GO:0075035 +name: appressorium maturation +namespace: biological_process +def: "The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "appressorium maturation on or near host" EXACT [] +synonym: "maturation of appressorium on or near host" RELATED [] +synonym: "maturation of symbiont appressorium on or near host" EXACT [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +relationship: part_of GO:0075016 ! appressorium formation + +[Term] +id: GO:0075036 +name: regulation of appressorium maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont appressorium maturation." [GOC:pamgo_curators] +synonym: "regulation of appressorium maturation on or near host" RELATED [] +synonym: "regulation of maturation of appressorium on or near host" EXACT [] +is_a: GO:0075017 ! regulation of appressorium formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075035 ! appressorium maturation +relationship: regulates GO:0075035 ! appressorium maturation + +[Term] +id: GO:0075037 +name: positive regulation of appressorium maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation." [GOC:pamgo_curators] +synonym: "positive regulation maturation of appressorium on or near host" EXACT [] +synonym: "positive regulation of appressorium maturation on or near host" RELATED [] +is_a: GO:0075018 ! positive regulation of appressorium formation +is_a: GO:0075036 ! regulation of appressorium maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075035 ! appressorium maturation +relationship: positively_regulates GO:0075035 ! appressorium maturation + +[Term] +id: GO:0075038 +name: negative regulation of appressorium maturation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation." [GOC:pamgo_curators] +synonym: "negative regulation of appressorium maturation on or near host" RELATED [] +synonym: "negative regulation of maturation of appressorium on or near host" EXACT [] +is_a: GO:0075019 ! negative regulation of appressorium formation +is_a: GO:0075036 ! regulation of appressorium maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075035 ! appressorium maturation +relationship: negatively_regulates GO:0075035 ! appressorium maturation + +[Term] +id: GO:0075039 +name: establishment of turgor in appressorium +namespace: biological_process +def: "The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "establishment of turgor in symbiont appressorium on or near host" EXACT [] +synonym: "formation of turgor in appressorium" EXACT [] +synonym: "generation of turgor in appressorium" EXACT [] +is_a: GO:0044115 ! development of symbiont involved in interaction with host +relationship: part_of GO:0075035 ! appressorium maturation + +[Term] +id: GO:0075040 +name: regulation of establishment of turgor in appressorium +namespace: biological_process +def: "Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium." [GOC:pamgo_curators] +synonym: "regulation of turgor formation in appressorium" RELATED [] +is_a: GO:0075036 ! regulation of appressorium maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075039 ! establishment of turgor in appressorium +relationship: regulates GO:0075039 ! establishment of turgor in appressorium + +[Term] +id: GO:0075041 +name: positive regulation of establishment of turgor in appressorium +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium." [GOC:pamgo_curators] +is_a: GO:0075037 ! positive regulation of appressorium maturation +is_a: GO:0075040 ! regulation of establishment of turgor in appressorium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075039 ! establishment of turgor in appressorium +relationship: positively_regulates GO:0075039 ! establishment of turgor in appressorium + +[Term] +id: GO:0075042 +name: negative regulation of establishment of turgor in appressorium +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium." [GOC:pamgo_curators] +is_a: GO:0075038 ! negative regulation of appressorium maturation +is_a: GO:0075040 ! regulation of establishment of turgor in appressorium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075039 ! establishment of turgor in appressorium +relationship: negatively_regulates GO:0075039 ! establishment of turgor in appressorium + +[Term] +id: GO:0075043 +name: melanization of appressorium wall +namespace: biological_process +def: "The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium." [GOC:pamgo_curators, Wikipedia:Appressorium] +synonym: "maintenance of turgor in appressorium by melanization" RELATED [] +synonym: "melanization of appressorium to maintain turgor pressure" EXACT [] +is_a: GO:0075035 ! appressorium maturation +relationship: has_part GO:0042438 ! melanin biosynthetic process + +[Term] +id: GO:0075044 +name: positive regulation by symbiont of host autophagy +namespace: biological_process +def: "Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "autophagy of host cells during interaction with symbiont" RELATED [GOC:dph] +synonym: "autophagy of host cells involved in interaction with symbiont" RELATED [] +synonym: "positive regulation by symbiont of host autophagotic process" RELATED [] +is_a: GO:0010508 ! positive regulation of autophagy +is_a: GO:0075071 ! modulation by symbiont of host autophagy +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: positively_regulates GO:0006914 ! autophagy + +[Term] +id: GO:0075045 +name: regulation of formation by symbiont of haustorium for nutrient acquisition from host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:0044127 ! regulation of development of symbiont in host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host +relationship: regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host + +[Term] +id: GO:0075046 +name: positive regulation of formation by symbiont of haustorium for nutrient acquisition from host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044129 ! positive regulation of development of symbiont in host +is_a: GO:0075045 ! regulation of formation by symbiont of haustorium for nutrient acquisition from host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host +relationship: positively_regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host + +[Term] +id: GO:0075047 +name: negative regulation of formation by symbiont of haustorium for nutrient acquisition from host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044131 ! negative regulation of development of symbiont in host +is_a: GO:0075045 ! regulation of formation by symbiont of haustorium for nutrient acquisition from host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host +relationship: negatively_regulates GO:0052094 ! formation by symbiont of haustorium for nutrient acquisition from host + +[Term] +id: GO:0075048 +name: obsolete cell wall strengthening in symbiont involved in entry into host +namespace: biological_process +def: "OBSOLETE. A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "cell wall strengthening in symbiont during entry into host" RELATED [GOC:tb] +synonym: "cell wall thickening in symbiont during entry into host" RELATED [] +synonym: "symbiont cell wall strengthening during entry into host" RELATED [] +is_obsolete: true + +[Term] +id: GO:0075049 +name: obsolete modulation of symbiont cell wall strengthening involved in entry into host +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for the obsoletion is that there is no evidence that those processes exist. +synonym: "modulation of symbiont cell wall strengthening during entry into host" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0075050 +name: obsolete positive regulation of symbiont cell wall strengthening involved in entry into host +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for the obsoletion is that there is no evidence that those processes exist. +synonym: "positive regulation of symbiont cell wall strengthening during entry into host" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0075051 +name: obsolete negative regulation of symbiont cell wall strengthening involved in entry into host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for the obsoletion is that there is no evidence that those processes exist. +synonym: "negative regulation of symbiont cell wall strengthening during entry into host" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0075053 +name: penetration peg formation +namespace: biological_process +alt_id: GO:0075057 +def: "The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators, PMID:26441323] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "formation of symbiont penetration peg for entry into host" RELATED [] +synonym: "initiation of symbiont penetration peg" NARROW [] +synonym: "symbiont penetration peg formation for entry into host" RELATED [] +synonym: "symbiont penetration peg initiation" NARROW [] +is_a: GO:0075015 ! formation of host infection structure +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18557 xsd:anyURI + +[Term] +id: GO:0075054 +name: modulation of penetration peg formation +namespace: biological_process +alt_id: GO:0075058 +def: "Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "modulation of symbiont penetration peg formation for entry into host" NARROW [] +synonym: "modulation of symbiont penetration peg initiation" NARROW [] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0052372 ! modulation by symbiont of entry into host +relationship: regulates GO:0075053 ! penetration peg formation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18557 xsd:anyURI + +[Term] +id: GO:0075055 +name: positive regulation of penetration peg formation +namespace: biological_process +alt_id: GO:0075059 +def: "Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "positive regulation of symbiont penetration peg formation for entry into host" NARROW [] +synonym: "positive regulation of symbiont penetration peg initiation" NARROW [] +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +is_a: GO:0075054 ! modulation of penetration peg formation +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0075053 ! penetration peg formation +relationship: positively_regulates GO:0075053 ! penetration peg formation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18557 xsd:anyURI + +[Term] +id: GO:0075056 +name: obsolete negative regulation of penetration peg formation +namespace: biological_process +alt_id: GO:0075060 +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont penetration peg formation for entry into host" NARROW [] +synonym: "negative regulation of symbiont penetration peg initiation" NARROW [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18779 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075062 +name: obsolete regulation of invasive hypha growth +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont invasive hypha formation in host" EXACT [] +synonym: "regulation of symbiont invasive hypha formation within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075063 +name: obsolete positive regulation of invasive hypha growth +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont invasive hypha formation in host" EXACT [] +synonym: "positive regulation of symbiont invasive hypha formation within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075064 +name: obsolete negative regulation invasive hypha growth +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont invasive hypha formation in host" EXACT [] +synonym: "negative regulation of symbiont invasive hypha formation within host" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075065 +name: obsolete growth or development of symbiont in host cell +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host cell ; GO:0044118' and 'growth of symbiont in host cell ; GO:0044119'. +synonym: "growth or development of symbiont in host cell" EXACT [] +is_obsolete: true +consider: GO:0044118 +consider: GO:0044119 + +[Term] +id: GO:0075066 +name: obsolete growth or development of symbiont in host organelle +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host organelle ; GO:0044120' and 'growth of symbiont in host organelle ; GO:0044121'. +synonym: "growth or development of symbiont in host organelle" EXACT [] +is_obsolete: true +consider: GO:0044120 +consider: GO:0044121 + +[Term] +id: GO:0075067 +name: obsolete growth or development of symbiont in host intercellular space +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development during symbiotic interaction ; GO:0044111' and 'growth of symbiont in host intercellular space ; GO:0044125'. +synonym: "growth or development of symbiont in host intercellular space" EXACT [] +is_obsolete: true +consider: GO:0044114 +consider: GO:0044117 + +[Term] +id: GO:0075068 +name: obsolete growth or development of symbiont in host vascular tissue +namespace: biological_process +def: "OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host vascular tissue ; GO:0044122' and 'growth of symbiont in host vascular tissue ; GO:0044123'. +synonym: "growth or development of symbiont in host vascular tissue" EXACT [] +is_obsolete: true +consider: GO:0044114 +consider: GO:0044117 + +[Term] +id: GO:0075069 +name: adhesion of symbiont infection cushion to host +namespace: biological_process +def: "The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont infection cushion to host during symbiotic interaction" EXACT [] +is_a: GO:0075001 ! adhesion of symbiont infection structure to host + +[Term] +id: GO:0075070 +name: adhesion of symbiont hyphopodium to host +namespace: biological_process +def: "The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont hyphopodium to host during symbiotic interaction" EXACT [] +is_a: GO:0075001 ! adhesion of symbiont infection structure to host + +[Term] +id: GO:0075071 +name: modulation by symbiont of host autophagy +namespace: biological_process +def: "Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "autophagy during symbiotic interaction" RELATED [GOC:dph] +synonym: "autophagy involved in symbiotic interaction" RELATED [] +synonym: "modulation by symbiont of host autophagic process" RELATED [] +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: regulates GO:0006914 ! autophagy + +[Term] +id: GO:0075072 +name: obsolete autophagy of symbiont cells involved in interaction with host +namespace: biological_process +def: "OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that this term did not represent any specific host/symbiont process. +synonym: "autophagy of symbiont cells during interaction with host" RELATED [GOC:dph] +is_obsolete: true + +[Term] +id: GO:0075073 +name: obsolete autophagy of symbiont cells on or near host surface +namespace: biological_process +def: "OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that this term did not represent any specific host/symbiont process. +is_obsolete: true + +[Term] +id: GO:0075074 +name: obsolete spore autophagy involved in appressorium formation on or near host +namespace: biological_process +def: "OBSOLETE. The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that this term did not represent any specific host/symbiont process. +synonym: "autophagy of spores during appressorium formation on or near host" EXACT [] +synonym: "spore autophagy during appressorium formation on or near host" RELATED [GOC:tb] +is_obsolete: true + +[Term] +id: GO:0075075 +name: modulation by host of symbiont adenylate cyclase activity +namespace: biological_process +def: "Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the host. To annotate symbiont gene products, consider the biological process term "modulation by symbiont of host adenylate cyclase activity ; GO:0075106". +is_a: GO:0045761 ! regulation of adenylate cyclase activity +is_a: GO:0052422 ! modulation by host of symbiont catalytic activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075076 +name: positive regulation by host of symbiont adenylate cyclase activity +namespace: biological_process +def: "Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0043947 ! positive regulation by host of symbiont catalytic activity +is_a: GO:0045762 ! positive regulation of adenylate cyclase activity +is_a: GO:0075075 ! modulation by host of symbiont adenylate cyclase activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: positively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075077 +name: negative regulation by host of symbiont adenylate cyclase activity +namespace: biological_process +def: "Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the host. To annotate symbiont gene products, consider the biological process term "negative regulation by symbiont of host adenylate cyclase activity ; GO:0075108". +is_a: GO:0007194 ! negative regulation of adenylate cyclase activity +is_a: GO:0052403 ! negative regulation by host of symbiont catalytic activity +is_a: GO:0075075 ! modulation by host of symbiont adenylate cyclase activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: negatively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075078 +name: obsolete modulation by host of symbiont receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075079 +name: obsolete positive regulation by host of symbiont receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075080 +name: obsolete negative regulation by host of symbiont receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075081 +name: obsolete modulation by host of symbiont transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075082 +name: obsolete positive regulation by host of symbiont transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075083 +name: obsolete negative regulation by host of symbiont transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075084 +name: obsolete modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "modulation by host of symbiont transmembrane receptor-mediated cAMP signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075085 +name: obsolete positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "activation by host of symbiont transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "positive regulation by host of symbiont transmembrane receptor-mediated cAMP signaling" EXACT [] +synonym: "promotion by host of symbiont transmembrane receptor protein activity involved in cAMP-mediated signal transduction" EXACT [] +synonym: "stimulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "upregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075086 +name: obsolete negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "downregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction" EXACT [] +synonym: "inhibition by host of symbiont transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "negative regulation by host of symbiont transmembrane receptor-mediated cAMP signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075087 +name: obsolete modulation by host of symbiont G protein-coupled receptor signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "modulation by host of symbiont G-protein coupled receptor protein signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075088 +name: obsolete positive regulation by host of symbiont G protein-coupled receptor signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "positive regulation by host of symbiont G-protein coupled receptor protein signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075089 +name: obsolete negative regulation by host of symbiont G protein-coupled receptor signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "negative regulation by host of symbiont G-protein coupled receptor protein signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075090 +name: obsolete modulation by host of symbiont signal transduction mediated by G-protein alpha subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075091 +name: obsolete positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075092 +name: obsolete negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075093 +name: obsolete modulation by host of symbiont signal transduction mediated by G-protein beta subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075094 +name: obsolete positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075095 +name: obsolete negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075096 +name: obsolete modulation by host of symbiont signal transduction mediated by G-protein gamma subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075097 +name: obsolete positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075098 +name: obsolete negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075099 +name: obsolete modulation by host of symbiont protein kinase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075100 +name: obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075101 +name: obsolete negative regulation by host of symbiont protein kinase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075102 +name: obsolete negative regulation by host of symbiont MAP kinase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075103 +name: obsolete modulation by host of symbiont calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "modulation by host of symbiont Ca++ or calmodulin-mediated signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075104 +name: obsolete positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "positive regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075105 +name: obsolete negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "negative regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075106 +name: modulation by symbiont of host adenylate cyclase activity +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont adenylate cyclase activity ; GO:0075075". +synonym: "Modulation by symbiont of host 3',5'-cyclic AMP synthetase activity" EXACT [] +synonym: "Modulation by symbiont of host adenyl cyclase activity" EXACT [] +synonym: "Modulation by symbiont of host adenylyl cyclase activity" EXACT [] +synonym: "Modulation by symbiont of host adenylylcyclase activity" EXACT [] +synonym: "Modulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity" EXACT [] +synonym: "Modulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity" EXACT [] +synonym: "Modulation by symbiont of host ATP pyrophosphate-lyase activity" EXACT [] +synonym: "Modulation by symbiont of host cAMP generating peptide activity" RELATED [] +is_a: GO:0045761 ! regulation of adenylate cyclase activity +is_a: GO:0052148 ! modulation by symbiont of host catalytic activity +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075107 +name: positive regulation by symbiont of host adenylate cyclase activity +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont adenylate cyclase activity ; GO:0075076". +synonym: "positive regulation by symbiont of host 3',5'-cyclic AMP synthetase activity" EXACT [] +synonym: "positive regulation by symbiont of host adenyl cyclase activity" EXACT [] +synonym: "positive regulation by symbiont of host adenylyl cyclase activity" EXACT [] +synonym: "positive regulation by symbiont of host adenylylcyclase activity" EXACT [] +synonym: "positive regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity" EXACT [] +is_a: GO:0043948 ! induction by symbiont of host catalytic activity +is_a: GO:0045762 ! positive regulation of adenylate cyclase activity +is_a: GO:0075106 ! modulation by symbiont of host adenylate cyclase activity +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: positively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075108 +name: negative regulation by symbiont of host adenylate cyclase activity +namespace: biological_process +def: "Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont adenylate cyclase activity ; GO:0075077". +synonym: "Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity" EXACT [] +synonym: "Negative regulation by symbiont of host adenyl cyclase activity" EXACT [] +synonym: "Negative regulation by symbiont of host adenylyl cyclase activity" EXACT [] +synonym: "Negative regulation by symbiont of host adenylylcyclase activity" EXACT [] +synonym: "Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity" EXACT [] +synonym: "Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity" EXACT [] +synonym: "Negative regulation by symbiont of host ATP pyrophosphate-lyase activity" EXACT [] +synonym: "Negative regulation by symbiont of host cAMP generating peptide activity" RELATED [] +is_a: GO:0007194 ! negative regulation of adenylate cyclase activity +is_a: GO:0052053 ! negative regulation by symbiont of host catalytic activity +is_a: GO:0075106 ! modulation by symbiont of host adenylate cyclase activity +intersection_of: GO:0052055 ! modulation by symbiont of host molecular function +intersection_of: negatively_regulates GO:0004016 ! adenylate cyclase activity + +[Term] +id: GO:0075109 +name: modulation by symbiont of host receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont receptor-mediated signal transduction ; GO:0075078". +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0075110 +name: induction by symbiont of host receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont receptor-mediated signal transduction ; GO:0075079". +synonym: "positive regulation by symbiont of host receptor-mediated signal transduction" EXACT [] +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0075109 ! modulation by symbiont of host receptor-mediated signal transduction + +[Term] +id: GO:0075111 +name: suppression by symbiont of host receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont receptor-mediated signal transduction ; GO:0075080". +synonym: "negative regulation by symbiont of host receptor-mediated signal transduction" EXACT [] +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +is_a: GO:0075109 ! modulation by symbiont of host receptor-mediated signal transduction + +[Term] +id: GO:0075112 +name: modulation by symbiont of host transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075081". +is_a: GO:0075109 ! modulation by symbiont of host receptor-mediated signal transduction + +[Term] +id: GO:0075113 +name: induction by symbiont of host transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075082". +synonym: "positive regulation by symbiont of host transmembrane receptor-mediated signal transduction" EXACT [] +is_a: GO:0075110 ! induction by symbiont of host receptor-mediated signal transduction +is_a: GO:0075112 ! modulation by symbiont of host transmembrane receptor-mediated signal transduction + +[Term] +id: GO:0075114 +name: suppression by symbiont of host transmembrane receptor-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075083". +synonym: "negative regulation by symbiont of host transmembrane receptor-mediated signal transduction" EXACT [] +is_a: GO:0075111 ! suppression by symbiont of host receptor-mediated signal transduction +is_a: GO:0075112 ! modulation by symbiont of host transmembrane receptor-mediated signal transduction + +[Term] +id: GO:0075115 +name: obsolete modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that this process exists. +synonym: "modulation by symbiont of host transmembrane receptor-mediated cAMP signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075116 +name: obsolete induction by symbiont of host transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that this process exists. +synonym: "activation by symbiont of host transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction" EXACT [] +synonym: "positive regulation by symbiont of host transmembrane receptor-mediated cAMP signaling" EXACT [] +synonym: "promotion by symbiont of host transmembrane receptor-mediated cAMP signal transduction" EXACT [] +synonym: "stimulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "upregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075117 +name: obsolete suppression by symbiont of host transmembrane receptor-mediated cAMP signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that this process exists. +synonym: "downregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction" EXACT [] +synonym: "inhibition by symbiont of host transmembrane receptor-mediated cAMP signal transduction" NARROW [] +synonym: "negative regulation by symbiont of host transmembrane receptor-mediated cAMP signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075118 +name: modulation by symbiont of host G protein-coupled receptor signal transduction +namespace: biological_process +alt_id: GO:0075121 +alt_id: GO:0075124 +alt_id: GO:0075127 +def: "Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont G protein-coupled receptor signal transduction ; GO:0075087". +synonym: "modulation by symbiont of host G-protein coupled receptor protein signal transduction" EXACT [] +synonym: "modulation by symbiont of host signal transduction mediated by G-protein alpha subunit" NARROW [] +synonym: "modulation by symbiont of host signal transduction mediated by G-protein beta subunit" NARROW [] +synonym: "modulation by symbiont of host signal transduction mediated by G-protein gamma subunit" NARROW [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0075112 ! modulation by symbiont of host transmembrane receptor-mediated signal transduction + +[Term] +id: GO:0075119 +name: induction by symbiont of host G protein-coupled receptor signal transduction +namespace: biological_process +alt_id: GO:0075122 +alt_id: GO:0075125 +alt_id: GO:0075128 +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by symbiont of host G protein-coupled receptor signal transduction ; GO:0075088". +synonym: "positive regulation by symbiont of host G protein-coupled receptor signal transduction" EXACT [] +synonym: "positive regulation by symbiont of host G-protein coupled receptor protein signal transduction" EXACT [] +synonym: "positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit" NARROW [] +synonym: "positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit" NARROW [] +synonym: "positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit" NARROW [] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0075113 ! induction by symbiont of host transmembrane receptor-mediated signal transduction +is_a: GO:0075118 ! modulation by symbiont of host G protein-coupled receptor signal transduction + +[Term] +id: GO:0075120 +name: suppression by symbiont of host G protein-coupled receptor signal transduction +namespace: biological_process +alt_id: GO:0075123 +alt_id: GO:0075126 +alt_id: GO:0075129 +def: "Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont G protein-coupled receptor signal transduction ; GO:0075089". +synonym: "negative regulation by symbiont of host G protein-coupled receptor signal transduction" EXACT [] +synonym: "negative regulation by symbiont of host G-protein coupled receptor protein signal transduction" EXACT [] +synonym: "negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit" NARROW [] +synonym: "negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit" NARROW [] +synonym: "negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit" NARROW [] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0075114 ! suppression by symbiont of host transmembrane receptor-mediated signal transduction +is_a: GO:0075118 ! modulation by symbiont of host G protein-coupled receptor signal transduction + +[Term] +id: GO:0075130 +name: modulation by symbiont of host protein kinase-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075099". +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0075131 +name: induction by symbiont of host protein kinase-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075100". +synonym: "positive regulation by symbiont of host protein kinase-mediated signal transduction" EXACT [] +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0075130 ! modulation by symbiont of host protein kinase-mediated signal transduction + +[Term] +id: GO:0075132 +name: suppression by symbiont of host protein kinase-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075101". +synonym: "negative regulation by symbiont of host protein kinase-mediated signal transduction" EXACT [] +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +is_a: GO:0075130 ! modulation by symbiont of host protein kinase-mediated signal transduction + +[Term] +id: GO:0075133 +name: modulation by symbiont of host calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075103". +synonym: "modulation by symbiont of host Ca++ or calmodulin-mediated signal transduction" EXACT [] +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0075134 +name: induction by symbiont of host calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075104". +synonym: "positive regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction" EXACT [] +synonym: "positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction" EXACT [] +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0075133 ! modulation by symbiont of host calcium or calmodulin-mediated signal transduction + +[Term] +id: GO:0075135 +name: suppression by symbiont of host calcium or calmodulin-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075105". +synonym: "negative regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction" EXACT [] +synonym: "negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction" EXACT [] +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +is_a: GO:0075133 ! modulation by symbiont of host calcium or calmodulin-mediated signal transduction + +[Term] +id: GO:0075136 +name: response to host +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "response of symbiont to host" RELATED [] +is_a: GO:0051701 ! interaction with host +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0075137 +name: response to host redox environment +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "response of symbiont to host redox environment" EXACT [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0075138 +name: response to host oxygen tension environment +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "response of symbiont to host oxygen tension environment" EXACT [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0075139 +name: response to host iron concentration +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "response of symbiont to host iron concentration" EXACT [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0075141 +name: symbiont tolerance to host environment +namespace: biological_process +alt_id: GO:0075142 +alt_id: GO:0075143 +alt_id: GO:0075144 +alt_id: GO:0075146 +alt_id: GO:0075238 +def: "Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "maintenance of symbiont tolerance to host environment" RELATED [] +synonym: "maintenance of symbiont tolerance to host iron concentration" NARROW [] +synonym: "maintenance of symbiont tolerance to host osmotic environment" NARROW [] +synonym: "maintenance of symbiont tolerance to host oxygen tension environment" NARROW [] +synonym: "maintenance of symbiont tolerance to host pH environment" NARROW [] +synonym: "maintenance of symbiont tolerance to host redox environment" NARROW [] +is_a: GO:0044403 ! symbiotic process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18827 xsd:anyURI + +[Term] +id: GO:0075147 +name: obsolete regulation of signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075148 +name: obsolete positive regulation of signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075149 +name: obsolete negative regulation of signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075150 +name: obsolete regulation of receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont receptor-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075151 +name: obsolete positive regulation of receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont receptor-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075152 +name: obsolete negative regulation of receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont receptor-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075153 +name: obsolete regulation of transmembrane receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont transmembrane receptor-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075154 +name: obsolete positive regulation of transmembrane receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0075155 +name: obsolete negative regulation of transmembrane receptor-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont transmembrane receptor-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075156 +name: obsolete regulation of G protein-coupled receptor signaling pathway in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of G-protein coupled receptor protein signaling pathway in response to host" EXACT [] +synonym: "regulation of G-protein coupled receptor protein signalling pathway in response to host" EXACT [GOC:mah] +synonym: "regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075157 +name: obsolete positive regulation of G protein-coupled receptor signaling pathway in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of G-protein coupled receptor protein signaling pathway in response to host" EXACT [] +synonym: "positive regulation of G-protein coupled receptor protein signalling pathway in response to host" EXACT [GOC:mah] +synonym: "positive regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075158 +name: obsolete negative regulation of G protein-coupled receptor signaling pathway in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of G-protein coupled receptor protein signaling pathway in response to host" EXACT [] +synonym: "negative regulation of G-protein coupled receptor protein signalling pathway in response to host" EXACT [GOC:mah] +synonym: "negative regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075159 +name: obsolete regulation of G-protein alpha subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075160 +name: obsolete positive regulation of G-protein alpha subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075161 +name: obsolete negative regulation of G-protein alpha subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075162 +name: obsolete regulation of G-protein beta subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075163 +name: obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075164 +name: obsolete negative regulation of G-protein beta subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075165 +name: obsolete regulation of G-protein gamma subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075166 +name: obsolete positive regulation of G-protein gamma subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075167 +name: obsolete negative regulation of G-protein gamma subunit-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075168 +name: obsolete regulation of protein kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont protein kinase-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075169 +name: obsolete positive regulation of symbiont protein kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0075170 +name: obsolete negative regulation of protein kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont protein kinase-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075171 +name: obsolete regulation of MAP kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont MAP kinase-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075172 +name: obsolete positive regulation of MAP kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont MAP kinase-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075173 +name: obsolete negative regulation of MAP kinase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont MAP kinase-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075174 +name: obsolete regulation of cAMP-mediated signaling in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of cAMP-mediated signal transduction in response to host" EXACT [] +synonym: "regulation of cAMP-mediated signalling in response to host" EXACT [] +synonym: "regulation of symbiont cAMP-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075175 +name: obsolete positive regulation of cAMP-mediated signaling in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of cAMP-mediated signal transduction in response to host" EXACT [] +synonym: "positive regulation of cAMP-mediated signalling in response to host" EXACT [] +synonym: "positive regulation of symbiont cAMP-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075176 +name: obsolete negative regulation of cAMP-mediated signaling in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of cAMP-mediated signal transduction in response to host" EXACT [] +synonym: "negative regulation of cAMP-mediated signalling in response to host" EXACT [] +synonym: "negative regulation of symbiont cAMP-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075177 +name: obsolete regulation of calcium or calmodulin-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "modulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host" EXACT [] +synonym: "modulation of symbiont calcium or calmodulin-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075178 +name: obsolete positive regulation of calcium or calmodulin-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host" EXACT [] +synonym: "positive regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075179 +name: obsolete negative regulation of calcium or calmodulin-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host" EXACT [] +synonym: "negative regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075180 +name: regulation of transcription in response to host +namespace: biological_process +def: "Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +synonym: "regulation of symbiont transcription in response to host" EXACT [] +is_a: GO:0075136 ! response to host +is_a: GO:2001141 ! regulation of RNA biosynthetic process + +[Term] +id: GO:0075181 +name: positive regulation of symbiont transcription in response to host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0075180 ! regulation of transcription in response to host + +[Term] +id: GO:0075182 +name: negative regulation of symbiont transcription in response to host +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0075180 ! regulation of transcription in response to host + +[Term] +id: GO:0075183 +name: infection cushion formation on or near host +namespace: biological_process +def: "The process in which an organized mass of hyphae is formed on or near the host organism, and numerous infective hyphae develop from the hyphae mass. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075015 ! formation of host infection structure + +[Term] +id: GO:0075184 +name: regulation of infection cushion formation on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075183 ! infection cushion formation on or near host +relationship: regulates GO:0075183 ! infection cushion formation on or near host + +[Term] +id: GO:0075185 +name: positive regulation of infection cushion formation on or near host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +is_a: GO:0075184 ! regulation of infection cushion formation on or near host +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075183 ! infection cushion formation on or near host +relationship: positively_regulates GO:0075183 ! infection cushion formation on or near host + +[Term] +id: GO:0075186 +name: negative regulation of infection cushion formation on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044147 ! negative regulation of development of symbiont involved in interaction with host +is_a: GO:0075184 ! regulation of infection cushion formation on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075183 ! infection cushion formation on or near host +relationship: negatively_regulates GO:0075183 ! infection cushion formation on or near host + +[Term] +id: GO:0075187 +name: hyphopodium formation on or near host +namespace: biological_process +def: "The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075015 ! formation of host infection structure + +[Term] +id: GO:0075188 +name: regulation of hyphopodium formation on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075187 ! hyphopodium formation on or near host +relationship: regulates GO:0075187 ! hyphopodium formation on or near host + +[Term] +id: GO:0075189 +name: positive regulation of hyphopodium formation on or near host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075188 ! regulation of hyphopodium formation on or near host +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075187 ! hyphopodium formation on or near host +relationship: positively_regulates GO:0075187 ! hyphopodium formation on or near host + +[Term] +id: GO:0075190 +name: negative regulation of hyphopodium formation on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075188 ! regulation of hyphopodium formation on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075187 ! hyphopodium formation on or near host +relationship: negatively_regulates GO:0075187 ! hyphopodium formation on or near host + +[Term] +id: GO:0075191 +name: obsolete autophagy of host cells on or near symbiont surface +namespace: biological_process +def: "OBSOLETE. The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that this term did not represent any specific host/symbiont process. +is_obsolete: true + +[Term] +id: GO:0075192 +name: haustorium mother cell formation on or near host +namespace: biological_process +def: "The process in which a symbiont cell is formed on or near its host organism, via separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075015 ! formation of host infection structure + +[Term] +id: GO:0075193 +name: regulation of haustorium mother cell formation on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075192 ! haustorium mother cell formation on or near host +relationship: regulates GO:0075192 ! haustorium mother cell formation on or near host + +[Term] +id: GO:0075194 +name: positive regulation of haustorium mother cell formation on or near host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075193 ! regulation of haustorium mother cell formation on or near host +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075192 ! haustorium mother cell formation on or near host +relationship: positively_regulates GO:0075192 ! haustorium mother cell formation on or near host + +[Term] +id: GO:0075195 +name: negative regulation of haustorium mother cell formation on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075193 ! regulation of haustorium mother cell formation on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075192 ! haustorium mother cell formation on or near host +relationship: negatively_regulates GO:0075192 ! haustorium mother cell formation on or near host + +[Term] +id: GO:0075196 +name: adhesion of symbiont haustorium mother cell to host +namespace: biological_process +def: "The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "adhesion of symbiont haustorium mother cell to host during symbiotic interaction" EXACT [] +is_a: GO:0075001 ! adhesion of symbiont infection structure to host + +[Term] +id: GO:0075197 +name: haustorium neck formation +namespace: biological_process +def: "The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators, Wikipedia:Haustorium] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "formation of symbiont haustorium neck for entry into host" RELATED [] +synonym: "symbiont haustorium neck formation for entry into host" RELATED [] +is_a: GO:0075015 ! formation of host infection structure +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18557 xsd:anyURI + +[Term] +id: GO:0075198 +name: modulation of symbiont haustorium neck formation for entry into host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +is_a: GO:0052372 ! modulation by symbiont of entry into host +relationship: regulates GO:0075197 ! haustorium neck formation + +[Term] +id: GO:0075199 +name: positive regulation of symbiont haustorium neck formation for entry into host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +is_a: GO:0075198 ! modulation of symbiont haustorium neck formation for entry into host +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0075197 ! haustorium neck formation +relationship: positively_regulates GO:0075197 ! haustorium neck formation + +[Term] +id: GO:0075200 +name: obsolete negative regulation of symbiont haustorium neck formation for entry into host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18779 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075201 +name: penetration hypha formation +namespace: biological_process +def: "The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators, PMID:26441323] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "formation of symbiont penetration hypha for entry into host" RELATED [] +synonym: "symbiont penetration hypha formation for entry into host" RELATED [] +is_a: GO:0075015 ! formation of host infection structure +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18557 xsd:anyURI + +[Term] +id: GO:0075202 +name: modulation of symbiont penetration hypha formation for entry into host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +is_a: GO:0052372 ! modulation by symbiont of entry into host +relationship: regulates GO:0075201 ! penetration hypha formation + +[Term] +id: GO:0075203 +name: positive regulation of symbiont penetration hypha formation for entry into host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +is_a: GO:0075202 ! modulation of symbiont penetration hypha formation for entry into host +is_a: GO:0075294 ! positive regulation by symbiont of entry into host +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0075201 ! penetration hypha formation +relationship: positively_regulates GO:0075201 ! penetration hypha formation + +[Term] +id: GO:0075204 +name: obsolete negative regulation of symbiont penetration hypha formation for entry into host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18779 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0075205 +name: obsolete modulation by host of symbiont cAMP-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "modulation by host of symbiont cAMP-mediated signaling" RELATED [] +synonym: "modulation by host of symbiont cAMP-mediated signalling" EXACT [] +synonym: "regulation by host of symbiont cAMP-mediated signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075206 +name: obsolete positive regulation by host of symbiont cAMP-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "positive regulation by host of symbiont cAMP-mediated signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075207 +name: obsolete negative regulation by host of symbiont cAMP-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +synonym: "negative regulation by host of symbiont cAMP-mediated signaling" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075208 +name: modulation by symbiont of host cAMP-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont cAMP-mediated signal transduction ; GO:0075205". +synonym: "modulation by symbiont of host cAMP-mediated signaling" EXACT [] +is_a: GO:0043949 ! regulation of cAMP-mediated signaling +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway + +[Term] +id: GO:0075209 +name: induction by symbiont of host cAMP-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075206". +synonym: "positive regulation by symbiont of host cAMP-mediated signal transduction" EXACT [] +synonym: "positive regulation by symbiont of host cAMP-mediated signaling" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0052028 ! induction by symbiont of host signal transduction pathway +is_a: GO:0075208 ! modulation by symbiont of host cAMP-mediated signal transduction + +[Term] +id: GO:0075210 +name: suppression by symbiont of host cAMP-mediated signal transduction +namespace: biological_process +def: "Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075207". +synonym: "negative regulation by symbiont of host cAMP-mediated signal transduction" EXACT [] +synonym: "negative regulation by symbiont of host cAMP-mediated signaling" EXACT [] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +is_a: GO:0075208 ! modulation by symbiont of host cAMP-mediated signal transduction + +[Term] +id: GO:0075211 +name: obsolete regulation of transmembrane receptor-mediated cAMP signaling in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host" EXACT [] +synonym: "regulation of transmembrane receptor-mediated cAMP signal transduction in response to host" EXACT [] +synonym: "regulation of transmembrane receptor-mediated cAMP signalling in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075212 +name: obsolete positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "positive regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host" RELATED [] +is_obsolete: true + +[Term] +id: GO:0075213 +name: obsolete negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "negative regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075214 +name: spore encystment on host +namespace: biological_process +def: "The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:kmv, GOC:pamgo_curators] +is_a: GO:0022611 ! dormancy process +is_a: GO:0044132 ! development of symbiont on or near host + +[Term] +id: GO:0075215 +name: modulation of spore encystment on host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0044138 ! modulation of development of symbiont on or near host +relationship: regulates GO:0075214 ! spore encystment on host + +[Term] +id: GO:0075216 +name: positive regulation of spore encystment on host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075215 ! modulation of spore encystment on host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075214 ! spore encystment on host +relationship: positively_regulates GO:0075214 ! spore encystment on host + +[Term] +id: GO:0075217 +name: negative regulation of spore encystment on host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075215 ! modulation of spore encystment on host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075214 ! spore encystment on host +relationship: negatively_regulates GO:0075214 ! spore encystment on host + +[Term] +id: GO:0075218 +name: zoospore encystment on host +namespace: biological_process +def: "The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0075214 ! spore encystment on host + +[Term] +id: GO:0075219 +name: modulation of zoospore encystment on host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0075215 ! modulation of spore encystment on host +relationship: regulates GO:0075218 ! zoospore encystment on host + +[Term] +id: GO:0075220 +name: positive regulation of zoospore encystment on host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0075216 ! positive regulation of spore encystment on host +is_a: GO:0075219 ! modulation of zoospore encystment on host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075218 ! zoospore encystment on host +relationship: positively_regulates GO:0075218 ! zoospore encystment on host + +[Term] +id: GO:0075221 +name: negative regulation of zoospore encystment on host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0075217 ! negative regulation of spore encystment on host +is_a: GO:0075219 ! modulation of zoospore encystment on host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075218 ! zoospore encystment on host +relationship: negatively_regulates GO:0075218 ! zoospore encystment on host + +[Term] +id: GO:0075222 +name: sporangium germination on or near host +namespace: biological_process +def: "The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth occurring on or near its host organism. A sporangium is a structure producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +synonym: "direct germination on or near host" NARROW [] +synonym: "germination of symbiont sporangium on or near host" EXACT [] +synonym: "symbiont sporangium germination on or near host" EXACT [] +is_a: GO:0043582 ! sporangium development +is_a: GO:0044132 ! development of symbiont on or near host +is_a: GO:0044703 ! multi-organism reproductive process + +[Term] +id: GO:0075223 +name: modulation of sporangium germination on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sporangium germination. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044138 ! modulation of development of symbiont on or near host +is_a: GO:0075310 ! regulation of sporangium development +relationship: regulates GO:0075222 ! sporangium germination on or near host + +[Term] +id: GO:0075224 +name: positive regulation of sporangium germination on or near host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044143 ! positive regulation of development of symbiont on or near host surface +is_a: GO:0075223 ! modulation of sporangium germination on or near host +is_a: GO:0075311 ! positive regulation of sporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075222 ! sporangium germination on or near host +relationship: positively_regulates GO:0075222 ! sporangium germination on or near host + +[Term] +id: GO:0075225 +name: negative regulation of sporangium germination on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044141 ! negative regulation of development of symbiont on or near host surface +is_a: GO:0075223 ! modulation of sporangium germination on or near host +is_a: GO:0075312 ! negative regulation of sporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075222 ! sporangium germination on or near host +relationship: negatively_regulates GO:0075222 ! sporangium germination on or near host + +[Term] +id: GO:0075226 +name: encysted zoospore germination on or near host +namespace: biological_process +def: "The physiological, developmental and morphological changes that occur in the symbiont encysted zoospore, which is on or near its host organism and germinates by developing a germ tube that may penetrate the host directly or indirectly through an appresorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075005 ! spore germination on or near host + +[Term] +id: GO:0075227 +name: modulation of encysted zoospore germination on or near host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075006 ! modulation of spore germination on or near host +relationship: regulates GO:0075226 ! encysted zoospore germination on or near host + +[Term] +id: GO:0075228 +name: positive regulation of encysted zoospore germination on or near host +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075007 ! positive regulation of spore germination on or near host +is_a: GO:0075227 ! modulation of encysted zoospore germination on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075226 ! encysted zoospore germination on or near host +relationship: positively_regulates GO:0075226 ! encysted zoospore germination on or near host + +[Term] +id: GO:0075229 +name: negative regulation of encysted zoospore germination on or near host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0075008 ! negative regulation of spore germination on or near host +is_a: GO:0075227 ! modulation of encysted zoospore germination on or near host +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075226 ! encysted zoospore germination on or near host +relationship: negatively_regulates GO:0075226 ! encysted zoospore germination on or near host + +[Term] +id: GO:0075230 +name: obsolete spore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075231 +name: obsolete modulation of spore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075232 +name: obsolete positive regulation of spore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075233 +name: obsolete negative regulation of spore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075234 +name: obsolete zoospore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "zoospore motility on or near host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075235 +name: obsolete modulation of zoospore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +synonym: "regulation of zoospore motility on or near host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075236 +name: obsolete positive regulation of zoospore movement on or near host +namespace: biological_process +def: "OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075237 +name: obsolete obsolete negative regulation of zoospore movement on or near host +namespace: biological_process +def: "OBSOLETE. OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it represented both a process and a location. +is_obsolete: true + +[Term] +id: GO:0075239 +name: zoospore formation +namespace: biological_process +def: "The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores." [GOC:pamgo_curators] +is_a: GO:0034300 ! sporangiospore formation + +[Term] +id: GO:0075240 +name: regulation of zoospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores." [GOC:pamgo_curators] +is_a: GO:0075286 ! regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075239 ! zoospore formation +relationship: regulates GO:0075239 ! zoospore formation + +[Term] +id: GO:0075241 +name: positive regulation of zoospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores." [GOC:pamgo_curators] +is_a: GO:0075240 ! regulation of zoospore formation +is_a: GO:0075287 ! positive regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075239 ! zoospore formation +relationship: positively_regulates GO:0075239 ! zoospore formation + +[Term] +id: GO:0075242 +name: negative regulation of zoospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores." [GOC:pamgo_curators] +is_a: GO:0075240 ! regulation of zoospore formation +is_a: GO:0075288 ! negative regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075239 ! zoospore formation +relationship: negatively_regulates GO:0075239 ! zoospore formation + +[Term] +id: GO:0075243 +name: oospore formation +namespace: biological_process +def: "The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi." [GOC:pamgo_curators] +is_a: GO:0043935 ! sexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0075244 +name: regulation of oospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes." [GOC:pamgo_curators] +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075243 ! oospore formation +relationship: regulates GO:0075243 ! oospore formation + +[Term] +id: GO:0075245 +name: positive regulation of oospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes." [GOC:pamgo_curators] +is_a: GO:0043941 ! positive regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075244 ! regulation of oospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075243 ! oospore formation +relationship: positively_regulates GO:0075243 ! oospore formation + +[Term] +id: GO:0075246 +name: negative regulation of oospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes." [GOC:pamgo_curators] +is_a: GO:0043942 ! negative regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075244 ! regulation of oospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075243 ! oospore formation +relationship: negatively_regulates GO:0075243 ! oospore formation + +[Term] +id: GO:0075247 +name: aeciospore formation +namespace: biological_process +def: "The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host." [GOC:pamgo_curators] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0075248 +name: regulation of aeciospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium." [GOC:pamgo_curators] +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075247 ! aeciospore formation +relationship: regulates GO:0075247 ! aeciospore formation + +[Term] +id: GO:0075249 +name: positive regulation of aeciospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium." [GOC:pamgo_curators] +is_a: GO:0043945 ! positive regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075248 ! regulation of aeciospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075247 ! aeciospore formation +relationship: positively_regulates GO:0075247 ! aeciospore formation + +[Term] +id: GO:0075250 +name: negative regulation of aeciospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium." [GOC:pamgo_curators] +is_a: GO:0043944 ! negative regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075248 ! regulation of aeciospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075247 ! aeciospore formation +relationship: negatively_regulates GO:0075247 ! aeciospore formation + +[Term] +id: GO:0075251 +name: uredospore formation +namespace: biological_process +def: "The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus." [GOC:pamgo_curators] +synonym: "urediniospore formation" EXACT [] +synonym: "ureidospore formation" EXACT [] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0075252 +name: regulation of uredospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium." [GOC:pamgo_curators] +synonym: "regulation of ureidospore formation" EXACT [] +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075251 ! uredospore formation +relationship: regulates GO:0075251 ! uredospore formation + +[Term] +id: GO:0075253 +name: positive regulation of uredospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium." [GOC:pamgo_curators] +synonym: "positive regulation of ureidospore formation" EXACT [] +is_a: GO:0043945 ! positive regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075252 ! regulation of uredospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075251 ! uredospore formation +relationship: positively_regulates GO:0075251 ! uredospore formation + +[Term] +id: GO:0075254 +name: negative regulation of uredospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium." [GOC:pamgo_curators] +synonym: "negative regulation of ureidospore formation" EXACT [] +is_a: GO:0043944 ! negative regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075252 ! regulation of uredospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075251 ! uredospore formation +relationship: negatively_regulates GO:0075251 ! uredospore formation + +[Term] +id: GO:0075255 +name: teliospore formation +namespace: biological_process +def: "The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs." [GOC:pamgo_curators] +is_a: GO:0043936 ! asexual sporulation resulting in formation of a cellular spore + +[Term] +id: GO:0075256 +name: regulation of teliospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs." [GOC:pamgo_curators] +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075255 ! teliospore formation +relationship: regulates GO:0075255 ! teliospore formation + +[Term] +id: GO:0075257 +name: positive regulation of teliospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs." [GOC:pamgo_curators] +is_a: GO:0043945 ! positive regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075256 ! regulation of teliospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075255 ! teliospore formation +relationship: positively_regulates GO:0075255 ! teliospore formation + +[Term] +id: GO:0075258 +name: negative regulation of teliospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs." [GOC:pamgo_curators] +is_a: GO:0043944 ! negative regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075256 ! regulation of teliospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075255 ! teliospore formation +relationship: negatively_regulates GO:0075255 ! teliospore formation + +[Term] +id: GO:0075259 +name: spore-bearing structure development +namespace: biological_process +def: "The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores." [GOC:di, GOC:mah, GOC:mcc, GOC:pamgo_curators] +synonym: "fruiting structure development" EXACT [] +synonym: "sporangium development" BROAD [] +synonym: "spore-bearing organ development" RELATED [] +synonym: "sporophore development" EXACT [] +is_a: GO:0048608 ! reproductive structure development +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0075260 +name: regulation of spore-bearing organ development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores." [GOC:pamgo_curators] +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075259 ! spore-bearing structure development +relationship: regulates GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075261 +name: positive regulation of spore-bearing organ development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores." [GOC:pamgo_curators] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0075260 ! regulation of spore-bearing organ development +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075259 ! spore-bearing structure development +relationship: positively_regulates GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075262 +name: negative regulation of spore-bearing organ development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores." [GOC:pamgo_curators] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0075260 ! regulation of spore-bearing organ development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075259 ! spore-bearing structure development +relationship: negatively_regulates GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075263 +name: oogonium development +namespace: biological_process +def: "The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes." [GOC:pamgo_curators] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075264 +name: regulation of oogonium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075263 ! oogonium development +relationship: regulates GO:0075263 ! oogonium development + +[Term] +id: GO:0075265 +name: positive regulation of oogonium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075264 ! regulation of oogonium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075263 ! oogonium development +relationship: positively_regulates GO:0075263 ! oogonium development + +[Term] +id: GO:0075266 +name: negative regulation of oogonium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075264 ! regulation of oogonium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075263 ! oogonium development +relationship: negatively_regulates GO:0075263 ! oogonium development + +[Term] +id: GO:0075267 +name: aecium development +namespace: biological_process +def: "The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium." [GOC:pamgo_curators] +is_a: GO:0030582 ! reproductive fruiting body development + +[Term] +id: GO:0075268 +name: regulation of aecium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed." [GOC:pamgo_curators] +is_a: GO:0031155 ! regulation of reproductive fruiting body development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075267 ! aecium development +relationship: regulates GO:0075267 ! aecium development + +[Term] +id: GO:0075269 +name: positive regulation of aecium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075268 ! regulation of aecium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075267 ! aecium development +relationship: positively_regulates GO:0075267 ! aecium development + +[Term] +id: GO:0075270 +name: negative regulation of aecium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075268 ! regulation of aecium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075267 ! aecium development +relationship: negatively_regulates GO:0075267 ! aecium development + +[Term] +id: GO:0075271 +name: zygosporangium development +namespace: biological_process +def: "The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes." [GOC:pamgo_curators] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075272 +name: regulation of zygosporangium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075271 ! zygosporangium development +relationship: regulates GO:0075271 ! zygosporangium development + +[Term] +id: GO:0075273 +name: positive regulation of zygosporangium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075272 ! regulation of zygosporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075271 ! zygosporangium development +relationship: positively_regulates GO:0075271 ! zygosporangium development + +[Term] +id: GO:0075274 +name: negative regulation of zygosporangium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075272 ! regulation of zygosporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075271 ! zygosporangium development +relationship: negatively_regulates GO:0075271 ! zygosporangium development + +[Term] +id: GO:0075275 +name: telium development +namespace: biological_process +def: "The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi." [GOC:pamgo_curators] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075276 +name: regulation of telium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075275 ! telium development +relationship: regulates GO:0075275 ! telium development + +[Term] +id: GO:0075277 +name: positive regulation of telium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075276 ! regulation of telium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075275 ! telium development +relationship: positively_regulates GO:0075275 ! telium development + +[Term] +id: GO:0075278 +name: negative regulation of telium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075276 ! regulation of telium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075275 ! telium development +relationship: negatively_regulates GO:0075275 ! telium development + +[Term] +id: GO:0075279 +name: uredinium development +namespace: biological_process +def: "The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores." [GOC:pamgo_curators] +synonym: "development of uredium" EXACT [] +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075280 +name: regulation of uredinium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075279 ! uredinium development +relationship: regulates GO:0075279 ! uredinium development + +[Term] +id: GO:0075281 +name: positive regulation of uredinium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075280 ! regulation of uredinium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075279 ! uredinium development +relationship: positively_regulates GO:0075279 ! uredinium development + +[Term] +id: GO:0075282 +name: negative regulation of uredinium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075280 ! regulation of uredinium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075279 ! uredinium development +relationship: negatively_regulates GO:0075279 ! uredinium development + +[Term] +id: GO:0075283 +name: sporulation resulting in formation of a multicellular or syncytial spore +namespace: biological_process +def: "The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure." [GOC:pamgo_curators] +synonym: "multicellular or syncytial spore formation by sporulation" EXACT [GOC:dph, GOC:tb] +is_a: GO:0043934 ! sporulation +property_value: RO:0002161 NCBITaxon:33083 + +[Term] +id: GO:0075284 +name: asexual sporulation resulting in formation of a multicellular or syncytial spore +namespace: biological_process +def: "The formation of a multicellular or syncytial spore via septations derived from mitosis." [GOC:pamgo_curators] +is_a: GO:0030436 ! asexual sporulation +is_a: GO:0075283 ! sporulation resulting in formation of a multicellular or syncytial spore + +[Term] +id: GO:0075285 +name: sexual sporulation resulting in formation of a multicellular or syncytial spore +namespace: biological_process +def: "The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction." [GOC:pamgo_curators] +is_a: GO:0034293 ! sexual sporulation +is_a: GO:0075283 ! sporulation resulting in formation of a multicellular or syncytial spore +intersection_of: GO:0075283 ! sporulation resulting in formation of a multicellular or syncytial spore +intersection_of: part_of GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0075286 +name: regulation of sporangiospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm." [GOC:pamgo_curators] +is_a: GO:0043943 ! regulation of asexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034300 ! sporangiospore formation +relationship: regulates GO:0034300 ! sporangiospore formation + +[Term] +id: GO:0075287 +name: positive regulation of sporangiospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm." [GOC:pamgo_curators] +is_a: GO:0043945 ! positive regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075286 ! regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034300 ! sporangiospore formation +relationship: positively_regulates GO:0034300 ! sporangiospore formation + +[Term] +id: GO:0075288 +name: negative regulation of sporangiospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm." [GOC:pamgo_curators] +is_a: GO:0043944 ! negative regulation of asexual sporulation resulting in formation of a cellular spore +is_a: GO:0075286 ! regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034300 ! sporangiospore formation +relationship: negatively_regulates GO:0034300 ! sporangiospore formation + +[Term] +id: GO:0075289 +name: aplanospore formation +namespace: biological_process +def: "The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell." [GOC:pamgo_curators] +is_a: GO:0034300 ! sporangiospore formation + +[Term] +id: GO:0075290 +name: regulation of aplanospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell." [GOC:pamgo_curators] +is_a: GO:0075286 ! regulation of sporangiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075289 ! aplanospore formation +relationship: regulates GO:0075289 ! aplanospore formation + +[Term] +id: GO:0075291 +name: positive regulation of aplanospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell." [GOC:pamgo_curators] +is_a: GO:0075287 ! positive regulation of sporangiospore formation +is_a: GO:0075290 ! regulation of aplanospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075289 ! aplanospore formation +relationship: positively_regulates GO:0075289 ! aplanospore formation + +[Term] +id: GO:0075292 +name: negative regulation of aplanospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell." [GOC:pamgo_curators] +is_a: GO:0075288 ! negative regulation of sporangiospore formation +is_a: GO:0075290 ! regulation of aplanospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075289 ! aplanospore formation +relationship: negatively_regulates GO:0075289 ! aplanospore formation + +[Term] +id: GO:0075293 +name: response to host pH environment +namespace: biological_process +def: "Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "response of symbiont to host pH environment" EXACT [] +is_a: GO:0075136 ! response to host + +[Term] +id: GO:0075294 +name: positive regulation by symbiont of entry into host +namespace: biological_process +alt_id: GO:0075295 +def: "Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "activation by organism of entry into other organism during symbiotic interaction" NARROW [] +synonym: "activation by symbiont of entry into host" NARROW [] +synonym: "positive regulation by organism of entry into other organism during symbiotic interaction" RELATED [GOC:tb] +synonym: "positive regulation by organism of entry into other organism involved in symbiotic interaction" RELATED [] +synonym: "up regulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "up regulation by symbiont of entry into host" EXACT [] +synonym: "up-regulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "up-regulation by symbiont of entry into host" EXACT [] +synonym: "upregulation by organism of entry into other organism during symbiotic interaction" RELATED [] +synonym: "upregulation by symbiont of entry into host" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0044409 ! entry into host +relationship: positively_regulates GO:0044409 ! entry into host +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19027 xsd:anyURI + +[Term] +id: GO:0075296 +name: positive regulation of ascospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus." [GOC:pamgo_curators] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0034307 ! regulation of ascospore formation +is_a: GO:0043941 ! positive regulation of sexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030437 ! ascospore formation +relationship: positively_regulates GO:0030437 ! ascospore formation + +[Term] +id: GO:0075297 +name: negative regulation of ascospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus." [GOC:pamgo_curators] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0034307 ! regulation of ascospore formation +is_a: GO:0043942 ! negative regulation of sexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030437 ! ascospore formation +relationship: negatively_regulates GO:0030437 ! ascospore formation + +[Term] +id: GO:0075298 +name: regulation of zygospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase." [GOC:pamgo_curators] +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034296 ! zygospore formation +relationship: regulates GO:0034296 ! zygospore formation + +[Term] +id: GO:0075299 +name: positive regulation of zygospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase." [GOC:pamgo_curators] +is_a: GO:0043941 ! positive regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075298 ! regulation of zygospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034296 ! zygospore formation +relationship: positively_regulates GO:0034296 ! zygospore formation + +[Term] +id: GO:0075300 +name: negative regulation of zygospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase." [GOC:pamgo_curators] +is_a: GO:0043942 ! negative regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075298 ! regulation of zygospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034296 ! zygospore formation +relationship: negatively_regulates GO:0034296 ! zygospore formation + +[Term] +id: GO:0075301 +name: obsolete cell differentiation involved in spore germination +namespace: biological_process +def: "OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a specific cell type occurring during spore germination, the physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth." [GOC:jl] +comment: This term was made obsolete because it describes a process that doesn't exist. +is_obsolete: true + +[Term] +id: GO:0075302 +name: regulation of basidiospore formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes." [GOC:pamgo_curators] +is_a: GO:0043940 ! regulation of sexual sporulation resulting in formation of a cellular spore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034295 ! basidiospore formation +relationship: regulates GO:0034295 ! basidiospore formation + +[Term] +id: GO:0075303 +name: positive regulation of basidiospore formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes." [GOC:pamgo_curators] +is_a: GO:0043941 ! positive regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075302 ! regulation of basidiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034295 ! basidiospore formation +relationship: positively_regulates GO:0034295 ! basidiospore formation + +[Term] +id: GO:0075304 +name: negative regulation of basidiospore formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes." [GOC:pamgo_curators] +is_a: GO:0043942 ! negative regulation of sexual sporulation resulting in formation of a cellular spore +is_a: GO:0075302 ! regulation of basidiospore formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034295 ! basidiospore formation +relationship: negatively_regulates GO:0034295 ! basidiospore formation + +[Term] +id: GO:0075305 +name: obsolete modulation of growth or development of symbiont on or near host +namespace: biological_process +def: "OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'modulation of growth of symbiont on or near host ; GO:0044139' and 'modulation of development of symbiont on or near host ; GO:0044138'. +synonym: "modulation of growth or development of symbiont on or near host" EXACT [] +synonym: "modulation of growth or development of symbiont on or near host surface" EXACT [] +is_obsolete: true +consider: GO:0044138 + +[Term] +id: GO:0075306 +name: regulation of conidium formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus." [GOC:di, GOC:pamgo_curators] +is_a: GO:0034305 ! regulation of asexual sporulation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048315 ! conidium formation +relationship: regulates GO:0048315 ! conidium formation +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 + +[Term] +id: GO:0075307 +name: positive regulation of conidium formation +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus." [GOC:di, GOC:pamgo_curators] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0043938 ! positive regulation of sporulation +is_a: GO:0075306 ! regulation of conidium formation +is_a: GO:1903666 ! positive regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048315 ! conidium formation +relationship: positively_regulates GO:0048315 ! conidium formation + +[Term] +id: GO:0075308 +name: negative regulation of conidium formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus." [GOC:di, GOC:pamgo_curators] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0043939 ! negative regulation of sporulation +is_a: GO:0075306 ! regulation of conidium formation +is_a: GO:1903665 ! negative regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048315 ! conidium formation +relationship: negatively_regulates GO:0048315 ! conidium formation + +[Term] +id: GO:0075309 +name: obsolete negative regulation of growth or development of symbiont on or near host surface +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'negative regulation of development of symbiont on or near host surface ; GO:0044141' and 'negative regulation of growth of symbiont on or near host surface ; GO:0044140'. +synonym: "negative regulation of growth or development of symbiont on or near host surface" EXACT [] +is_obsolete: true +consider: GO:0044141 + +[Term] +id: GO:0075310 +name: regulation of sporangium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043582 ! sporangium development +relationship: regulates GO:0043582 ! sporangium development + +[Term] +id: GO:0075311 +name: positive regulation of sporangium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075310 ! regulation of sporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043582 ! sporangium development +relationship: positively_regulates GO:0043582 ! sporangium development + +[Term] +id: GO:0075312 +name: negative regulation of sporangium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075310 ! regulation of sporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043582 ! sporangium development +relationship: negatively_regulates GO:0043582 ! sporangium development + +[Term] +id: GO:0075313 +name: basidium development +namespace: biological_process +def: "The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi." [GOC:di, GOC:mah, GOC:mcc, GOC:pamgo_curators] +comment: Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked. +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075314 +name: regulation of basidium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075313 ! basidium development +relationship: regulates GO:0075313 ! basidium development + +[Term] +id: GO:0075315 +name: positive regulation of basidium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075314 ! regulation of basidium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075313 ! basidium development +relationship: positively_regulates GO:0075313 ! basidium development + +[Term] +id: GO:0075316 +name: negative regulation of basidium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075314 ! regulation of basidium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075313 ! basidium development +relationship: negatively_regulates GO:0075313 ! basidium development + +[Term] +id: GO:0075317 +name: ascus development +namespace: biological_process +def: "The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed." [GOC:di, GOC:mah, GOC:mcc, GOC:pamgo_curators] +comment: Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked. +is_a: GO:0075259 ! spore-bearing structure development + +[Term] +id: GO:0075318 +name: regulation of ascus development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed." [GOC:pamgo_curators] +is_a: GO:0075260 ! regulation of spore-bearing organ development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075317 ! ascus development +relationship: regulates GO:0075317 ! ascus development + +[Term] +id: GO:0075319 +name: positive regulation of ascus development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed." [GOC:pamgo_curators] +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:0075318 ! regulation of ascus development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075317 ! ascus development +relationship: positively_regulates GO:0075317 ! ascus development + +[Term] +id: GO:0075320 +name: negative regulation of ascus development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed." [GOC:pamgo_curators] +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:0075318 ! regulation of ascus development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075317 ! ascus development +relationship: negatively_regulates GO:0075317 ! ascus development + +[Term] +id: GO:0075321 +name: oomycete sporangium development +namespace: biological_process +def: "The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated." [GOC:pamgo_curators] +is_a: GO:0030436 ! asexual sporulation +is_a: GO:0043582 ! sporangium development + +[Term] +id: GO:0075322 +name: regulation of oomycete sporangium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated." [GOC:pamgo_curators] +is_a: GO:0034305 ! regulation of asexual sporulation +is_a: GO:0075310 ! regulation of sporangium development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075321 ! oomycete sporangium development +relationship: regulates GO:0075321 ! oomycete sporangium development + +[Term] +id: GO:0075323 +name: positive regulation of oomycete sporangium development +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated." [GOC:pamgo_curators] +is_a: GO:0043938 ! positive regulation of sporulation +is_a: GO:0075311 ! positive regulation of sporangium development +is_a: GO:0075322 ! regulation of oomycete sporangium development +is_a: GO:1903666 ! positive regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075321 ! oomycete sporangium development +relationship: positively_regulates GO:0075321 ! oomycete sporangium development + +[Term] +id: GO:0075324 +name: negative regulation of oomycete sporangium development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated." [GOC:pamgo_curators] +is_a: GO:0043939 ! negative regulation of sporulation +is_a: GO:0075312 ! negative regulation of sporangium development +is_a: GO:0075322 ! regulation of oomycete sporangium development +is_a: GO:1903665 ! negative regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075321 ! oomycete sporangium development +relationship: negatively_regulates GO:0075321 ! oomycete sporangium development + +[Term] +id: GO:0075325 +name: spore dispersal +namespace: biological_process +alt_id: GO:0075326 +alt_id: GO:0075327 +def: "Any process in which an organism disseminates its spores." [Wikipedia:Spore] +synonym: "active spore dispersal on or near host" NARROW [] +synonym: "active spore dispersal on or near host during symbiotic interaction" NARROW [] +synonym: "passive spore dispersal on or near host" NARROW [] +synonym: "spore dispersal on or near host" NARROW [] +synonym: "spore dispersal on or near host during symbiotic interaction" EXACT [] +is_a: GO:0000003 ! reproduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18823 xsd:anyURI + +[Term] +id: GO:0075328 +name: formation by symbiont of arbuscule for nutrient acquisition from host +namespace: biological_process +def: "The assembly by an organism of an arbuscule, a fine, tree-like hyphal structure projected into the host cell for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0052093 ! formation of specialized structure for nutrient acquisition from host + +[Term] +id: GO:0075329 +name: regulation of arbuscule formation for nutrient acquisition from host +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0044145 ! modulation of development of symbiont involved in interaction with host +is_a: GO:0060259 ! regulation of feeding behavior +relationship: regulates GO:0075328 ! formation by symbiont of arbuscule for nutrient acquisition from host + +[Term] +id: GO:0075330 +name: positive regulation of arbuscule formation for nutrient acquisition from host +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044149 ! positive regulation of development of symbiont involved in interaction with host +is_a: GO:0075329 ! regulation of arbuscule formation for nutrient acquisition from host +relationship: positively_regulates GO:0075328 ! formation by symbiont of arbuscule for nutrient acquisition from host + +[Term] +id: GO:0075331 +name: negative regulation of arbuscule formation for nutrient acquisition from host +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. +is_a: GO:0044147 ! negative regulation of development of symbiont involved in interaction with host +is_a: GO:0075329 ! regulation of arbuscule formation for nutrient acquisition from host +relationship: negatively_regulates GO:0075328 ! formation by symbiont of arbuscule for nutrient acquisition from host + +[Term] +id: GO:0075332 +name: obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075333 +name: obsolete positive regulation by host of symbiont adenylate cyclase-mediated signal transduction +namespace: biological_process +def: "OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway. +is_obsolete: true + +[Term] +id: GO:0075334 +name: obsolete modulation of symbiont adenylate cyclase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0075335 +name: obsolete positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0075336 +name: obsolete negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host +namespace: biological_process +def: "OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0075337 +name: obsolete positive regulation of growth or development of symbiont on or near host surface +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism." [GOC:pamgo_curators] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'positive regulation of development of symbiont on or near host surface ; GO:0044143' and 'positive regulation of growth of symbiont on or near host surface ; GO:0044142'. +synonym: "positive regulation of growth or development of symbiont on or near host surface" EXACT [] +is_obsolete: true +consider: GO:0044143 + +[Term] +id: GO:0075338 +name: obsolete modulation of growth or development of symbiont during interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'modulation of development of symbiont during interaction with host ; GO:0044145' and 'modulation of growth of symbiont during interaction with host ; GO:0044144'. +synonym: "modulation of growth or development of symbiont during interaction with host" EXACT [] +is_obsolete: true +consider: GO:0044145 + +[Term] +id: GO:0075339 +name: obsolete positive regulation of growth or development of symbiont during interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'positive regulation of development of symbiont during interaction with host ; GO:0044149' and 'positive regulation of growth of symbiont during interaction with host ; GO:0044148'. +synonym: "positive regulation of growth or development of symbiont during interaction with host" EXACT [] +is_obsolete: true + +[Term] +id: GO:0075340 +name: obsolete negative regulation of growth or development of symbiont during interaction with host +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism." [GOC:jl] +comment: This term was made obsolete because it contained a conjunction (or). It has been replaced with 'negative regulation of development of symbiont during interaction with host ; GO:0044147'. +synonym: "negative regulation of growth or development of symbiont during interaction with host" EXACT [] +is_obsolete: true +consider: GO:0044147 + +[Term] +id: GO:0075341 +name: host cell PML body +namespace: cellular_component +def: "A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism." [GOC:BHF, GOC:jl] +synonym: "host cell PML NB" EXACT [] +synonym: "host cell PML nuclear body" EXACT [] +is_a: GO:0044094 ! host cell nuclear part + +[Term] +id: GO:0075342 +name: disruption by symbiont of host cell PML body +namespace: biological_process +def: "The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:BHF, GOC:jl] +synonym: "catabolism by symbiont of host cell PML body" EXACT [] +synonym: "degradation by symbiont of host cell PML body" EXACT [] +synonym: "disassembly by symbiont of host cell PML body" EXACT [] +synonym: "disassembly by symbiont of host cell PML body during symbiotic interaction" EXACT [] +synonym: "disassembly by symbiont of host cell PML NB" EXACT [] +synonym: "disassembly by symbiont of host cell PML nuclear body" EXACT [] +is_a: GO:0052008 ! disruption by symbiont of host cellular component + +[Term] +id: GO:0075343 +name: modulation by symbiont of abscisic acid levels in host +namespace: biological_process +def: "The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate abscisic acid levels in the host, consider annotating to 'regulation of abscisic acid mediated signaling ; GO:0009787' or 'regulation of abscisic acid biosynthetic process ; GO:0010115'. +is_a: GO:0052019 ! modulation by symbiont of host hormone or growth regulator levels + +[Term] +id: GO:0075344 +name: obsolete modulation by symbiont of host protein levels +namespace: biological_process +def: "OBSOLETE. The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true + +[Term] +id: GO:0075345 +name: modification by symbiont of host protein +namespace: biological_process +def: "The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is intended for use in annotation of symbiont gene products. For host gene products that modify host proteins, consider annotation to 'protein modification process' GO:0006464. +is_a: GO:0052228 ! metabolism by symbiont of host protein + +[Term] +id: GO:0075346 +name: modification by symbiont of host protein by ubiquitination +namespace: biological_process +def: "The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: Note that this term is intended for use in annotation of symbiont gene products. For host gene products that ubiquitinate host proteins, consider annotation to 'protein ubiquitination ; GO:0016567'. +synonym: "modification by symbiont of host protein by ubiquitinylation" EXACT [] +synonym: "modification by symbiont of host protein by ubiquitylation" EXACT [] +is_a: GO:0075345 ! modification by symbiont of host protein + +[Term] +id: GO:0075502 +name: endosome membrane permeabilization involved in viral entry into host cell +namespace: biological_process +alt_id: GO:0075518 +def: "Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm." [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane" RELATED [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization" RELATED [GOC:bf, GOC:jl] +is_a: GO:0039665 ! permeabilization of host organelle membrane involved in viral entry into host cell +created_by: jl +creation_date: 2010-06-02T02:40:25Z + +[Term] +id: GO:0075503 +name: fusion of virus membrane with host macropinosome membrane +namespace: biological_process +def: "Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm." [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane" EXACT [] +synonym: "viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane" RELATED [GOC:bf, GOC:jl] +is_a: GO:0039654 ! fusion of virus membrane with host endosome membrane +created_by: jl +creation_date: 2010-06-02T02:45:47Z + +[Term] +id: GO:0075504 +name: macropinosomal membrane permeabilization involved in viral entry into host cell +namespace: biological_process +def: "Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm." [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization" RELATED [GOC:bf, GOC:jl] +is_a: GO:0039665 ! permeabilization of host organelle membrane involved in viral entry into host cell +created_by: jl +creation_date: 2010-06-02T02:48:36Z + +[Term] +id: GO:0075505 +name: entry of intact viral capsid into host nucleus through nuclear pore complex +namespace: biological_process +def: "Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC)." [PMID:22929056, VZ:989] +comment: This mechanism is used by viruses with capsids small enough to cross the nuclear pore complex, such as the single-stranded (ss) DNA viruses Parvoviridae, Circoviridae and Geminiviridae. +is_a: GO:0075732 ! viral penetration into host nucleus +created_by: jl +creation_date: 2011-07-26T04:35:03Z + +[Term] +id: GO:0075506 +name: entry of viral genome into host nucleus through nuclear pore complex via importin +namespace: biological_process +def: "Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery." [PMID:22929056, VZ:989] +comment: This mechanism is used by some RNA viruses (e.g. Orthomyxoviridae), some dsDNA viruses (e.g. Polyomaviridae) and some ssRNA viruses (e.g. Lentivirus). +synonym: "entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex" EXACT [GOC:jl] +is_a: GO:0075732 ! viral penetration into host nucleus +created_by: jl +creation_date: 2011-07-26T04:36:46Z + +[Term] +id: GO:0075507 +name: entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome +namespace: biological_process +def: "Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm." [PMID:22929056, VZ:989] +comment: This mechanism is used by viruses such as Herpesvirales whose capsid is too large to enter the nuclear pore complex (NPC) pore. +is_a: GO:0075732 ! viral penetration into host nucleus +created_by: jl +creation_date: 2011-07-26T04:52:51Z + +[Term] +id: GO:0075508 +name: entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm +namespace: biological_process +def: "Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm." [PMID:22929056, VZ:989] +comment: This mechanism is used by viruses such as Hepadnaviridae whose capsids enter the NPC but are too big to pass intact into the nucleus. +synonym: "entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm" EXACT [GOC:jl] +is_a: GO:0075732 ! viral penetration into host nucleus +created_by: jl +creation_date: 2011-07-26T04:56:10Z + +[Term] +id: GO:0075509 +name: endocytosis involved in viral entry into host cell +namespace: biological_process +def: "Any endocytosis that is involved in the uptake of a virus into a host cell." [GOC:bf, GOC:jl, VZ:977] +synonym: "viral entry into host cell via endocytosis" RELATED [GOC:bf, GOC:jl] +synonym: "viral penetration via endocytosis followed by endosome disruption" EXACT [] +synonym: "virus endocytosis by host" EXACT [UniProtKB-KW:KW-1164] +xref: VZ:977 "Virus endocytosis by host" +is_a: GO:0006897 ! endocytosis +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0046794 ! transport of virus +intersection_of: GO:0006897 ! endocytosis +intersection_of: part_of GO:0046718 ! viral entry into host cell +relationship: part_of GO:0046718 ! viral entry into host cell +created_by: jl +creation_date: 2011-07-27T11:06:34Z + +[Term] +id: GO:0075510 +name: macropinocytosis involved in viral entry into host cell +namespace: biological_process +def: "Any macropinocytosis that is involved in the uptake of a virus into a host cell." [GOC:jl, GOC:sp, PMID:17077125, PMID:19404330, VZ:800] +synonym: "viral entry into host cell via macropinocytosis" RELATED [GOC:bf, GOC:jl] +xref: VZ:800 "Macropinocytosis of virus by host" +is_a: GO:0075509 ! endocytosis involved in viral entry into host cell +is_a: GO:1902539 ! multi-organism macropinocytosis +intersection_of: GO:1902539 ! multi-organism macropinocytosis +intersection_of: part_of GO:0046718 ! viral entry into host cell +created_by: jl +creation_date: 2011-07-27T11:24:59Z + +[Term] +id: GO:0075511 +name: macropinosome lysis involved in viral entry into host cell +namespace: biological_process +def: "Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm." [GOC:bf, GOC:jl] +is_a: GO:0039664 ! lysis of host organelle involved in viral entry into host cell +created_by: jl +creation_date: 2011-07-27T11:38:07Z + +[Term] +id: GO:0075512 +name: clathrin-dependent endocytosis of virus by host cell +namespace: biological_process +alt_id: GO:0075516 +def: "Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus." [GOC:bf, GOC:jl, VZ:957] +synonym: "clathrin-mediated endocytosis of virus by host cell" EXACT [] +synonym: "viral entry into host cell via clathrin-mediated endocytosis" RELATED [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis" NARROW [] +synonym: "viral penetration via clathrin-mediated endocytosis" EXACT [GOC:sp] +xref: VZ:957 "Clathrin-mediated endocytosis of virus by host" +is_a: GO:0019065 ! receptor-mediated endocytosis of virus by host cell +is_a: GO:0072583 ! clathrin-dependent endocytosis +intersection_of: GO:0072583 ! clathrin-dependent endocytosis +intersection_of: part_of GO:0046718 ! viral entry into host cell +created_by: jl +creation_date: 2011-07-27T02:08:54Z + +[Term] +id: GO:0075513 +name: caveolin-mediated endocytosis of virus by host cell +namespace: biological_process +def: "Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus." [GOC:bf, GOC:jl, VZ:976] +synonym: "viral entry into host cell via caveolae-mediated endocytosis" EXACT [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via caveolin-mediated endocytosis" RELATED [GOC:bf, GOC:jl] +synonym: "viral penetration via caveolae-mediated endocytosis followed by endosome disruption" EXACT [] +xref: VZ:976 "Caveolin-mediated endocytosis of virus by host" +is_a: GO:0019065 ! receptor-mediated endocytosis of virus by host cell +is_a: GO:0072584 ! caveolin-mediated endocytosis +intersection_of: GO:0072584 ! caveolin-mediated endocytosis +intersection_of: part_of GO:0046718 ! viral entry into host cell +created_by: jl +creation_date: 2011-07-27T02:40:04Z + +[Term] +id: GO:0075514 +name: endosome lysis involved in viral entry into host cell +namespace: biological_process +def: "Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm." [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis" EXACT [GOC:bf, GOC:jl] +is_a: GO:0039664 ! lysis of host organelle involved in viral entry into host cell +created_by: jl +creation_date: 2011-07-27T02:56:15Z + +[Term] +id: GO:0075515 +name: obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane +namespace: biological_process +def: "OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane." [GOC:jl, VZ:976] +comment: This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis. +synonym: "viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane" EXACT [GOC:bf, GOC:jl] +synonym: "viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2011-07-27T02:57:55Z + +[Term] +id: GO:0075519 +name: microtubule-dependent intracellular transport of viral material +namespace: biological_process +def: "The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus." [VZ:983] +is_a: GO:0075733 ! intracellular transport of virus +created_by: jl +creation_date: 2011-08-03T01:45:25Z + +[Term] +id: GO:0075520 +name: actin-dependent intracellular transport of virus +namespace: biological_process +def: "The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions." [UniProtKB-KW:KW-1178, VZ:991] +synonym: "actin-dependent intracellular transport of viral material" EXACT [] +xref: VZ:991 "Actin-dependent inwards viral transport" +is_a: GO:0075733 ! intracellular transport of virus +created_by: jl +creation_date: 2011-08-03T01:45:55Z + +[Term] +id: GO:0075521 +name: microtubule-dependent intracellular transport of viral material towards nucleus +namespace: biological_process +def: "The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules." [UniProtKB-KW:KW-1177, VZ:983] +synonym: "microtubule-dependent intracellular transport of viral material to nucleus" EXACT [GOC:jl] +xref: VZ:983 "Microtubular inwards viral transport" +is_a: GO:0075519 ! microtubule-dependent intracellular transport of viral material +is_a: GO:0075606 ! transport of viral material towards nucleus +created_by: jl +creation_date: 2011-08-03T02:09:21Z + +[Term] +id: GO:0075522 +name: IRES-dependent viral translational initiation +namespace: biological_process +def: "Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation." [GOC:bf, GOC:jl, PMID:19632368, VZ:867] +xref: VZ:867 "Viral initiation of translation: IRES and DLP" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019081 ! viral translation +created_by: jl +creation_date: 2011-08-03T02:25:03Z + +[Term] +id: GO:0075523 +name: viral translational frameshifting +namespace: biological_process +def: "A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins." [GOC:bf, GOC:ch, GOC:jl, PMID:24825891, PMID:8852897, VZ:860] +comment: This term is intended to annotate gene products involved in the process of viral translational frameshifting, not viral proteins produced by this translation process. +synonym: "ribosomal frameshifting involved in viral translation" EXACT [GOC:jl] +xref: VZ:860 "Ribosomal frameshifting" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019081 ! viral translation +created_by: jl +creation_date: 2011-08-03T02:48:46Z + +[Term] +id: GO:0075524 +name: ribosomal skipping +namespace: biological_process +def: "A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue." [GOC:bf, GOC:ch, GOC:jl, VZ:914] +comment: This term is intended to annotate gene products involved in the process of ribosomal skipping, not viral proteins produced by this translation process. +xref: VZ:914 "Ribosomal skipping" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019081 ! viral translation +created_by: jl +creation_date: 2011-08-03T03:19:37Z + +[Term] +id: GO:0075525 +name: viral translational termination-reinitiation +namespace: biological_process +def: "A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF." [GOC:bf, GOC:ch, GOC:jl, PMID:18631147, PMID:18824510, VZ:858] +comment: This term is intended to annotate gene products involved in the process of viral translational termination-reinitiation, not viral proteins produced by this translation process. +synonym: "termination reinitiation involved in viral translation" EXACT [GO:jl] +synonym: "viral translation involving termination re-initiation" EXACT [GO:jl] +synonym: "viral translation involving termination-reinitiation" EXACT [GO:jl] +synonym: "viral translation involving translational stop-start" EXACT [GO:jl] +xref: VZ:858 "RNA termination-reinitiation" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019081 ! viral translation +created_by: jl +creation_date: 2011-08-04T12:01:22Z + +[Term] +id: GO:0075526 +name: cap snatching +namespace: biological_process +def: "A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs." [GOC:bf, GOC:jl, VZ:839] +synonym: "cap snatching involved in viral mRNA transcription" EXACT [GO:jl] +xref: VZ:839 +is_a: GO:0016032 ! viral process +relationship: part_of GO:0039697 ! negative stranded viral RNA transcription +created_by: jl +creation_date: 2011-08-04T01:19:00Z + +[Term] +id: GO:0075527 +name: viral RNA editing +namespace: biological_process +def: "The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon." [PMID:1629949, VZ:857] +synonym: "RNA editing involved in viral mRNA transcription" EXACT [GO:jl] +xref: VZ:857 "RNA editing" +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019083 ! viral transcription +created_by: jl +creation_date: 2011-08-04T02:07:03Z + +[Term] +id: GO:0075528 +name: modulation by virus of host immune response +namespace: biological_process +def: "The process in which a virus effects a change in the host immune response." [GOC:bf, GOC:jl] +synonym: "regulation by virus of host immune system process" EXACT [GOC:jl] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052553 ! modulation by symbiont of host immune response +created_by: jl +creation_date: 2011-08-04T02:47:57Z + +[Term] +id: GO:0075529 +name: establishment of latency as a circular episome +namespace: biological_process +def: "A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure." [GOC:jl] +synonym: "establishment of circular plasmid latency" EXACT [] +synonym: "establishment of latency as a circular plasmid" EXACT [] +is_a: GO:0075720 ! establishment of episomal latency +created_by: jl +creation_date: 2011-08-04T03:08:17Z + +[Term] +id: GO:0075530 +name: establishment of latency as a linear episome +namespace: biological_process +def: "A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure." [GOC:jl] +synonym: "establishment of latency as a linear plasmid" EXACT [] +synonym: "establishment of linear plasmid latency" EXACT [] +is_a: GO:0075720 ! establishment of episomal latency +created_by: jl +creation_date: 2011-08-04T03:14:23Z + +[Term] +id: GO:0075606 +name: transport of viral material towards nucleus +namespace: biological_process +def: "The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane." [GOC:bf, GOC:jl, VZ:990] +comment: This process does not include the viral material crossing the nuclear membrane. For transport of viral material into the nucleus, consider instead: 'viral penetration into host nucleus ; GO:0075732'. +synonym: "cytoplasmic inwards viral transport" EXACT [UniProtKB-KW:KW-1176, VZ:990] +synonym: "transport of viral material to nucleus" EXACT [GOC:jl] +synonym: "viral genome transport to host cell nucleus" EXACT [] +xref: VZ:990 "Cytoplasmic inwards viral transport" +is_a: GO:0075733 ! intracellular transport of virus +created_by: jl +creation_date: 2009-11-05T03:33:36Z + +[Term] +id: GO:0075705 +name: obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane +namespace: biological_process +def: "OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane." [GOC:jl] +comment: This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis. +synonym: "viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane" EXACT [] +synonym: "viral penetration via endocytosis followed by genetic injection through the endosome membrane" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2009-04-23T02:08:06Z + +[Term] +id: GO:0075713 +name: establishment of integrated proviral latency +namespace: biological_process +alt_id: GO:0019047 +def: "A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage." [GOC:jl] +synonym: "prophage integration" EXACT [] +synonym: "provirus integration" EXACT [] +xref: VZ:980 "Viral genome integration" +is_a: GO:0019043 ! establishment of viral latency +relationship: has_part GO:0044826 ! viral genome integration into host DNA +created_by: jl +creation_date: 2009-05-07T02:28:41Z + +[Term] +id: GO:0075720 +name: establishment of episomal latency +namespace: biological_process +def: "A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity." [GOC:jl] +synonym: "establishment as a plasmid prophage" NARROW [] +synonym: "establishment of plasmid latency" EXACT [] +is_a: GO:0019043 ! establishment of viral latency +created_by: jl +creation_date: 2009-11-26T03:57:44Z + +[Term] +id: GO:0075732 +name: viral penetration into host nucleus +namespace: biological_process +def: "The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid." [PMID:22929056, VZ:989] +synonym: "viral entry into host nucleus" EXACT [] +synonym: "viral import into host nucleus" EXACT [] +xref: VZ:989 "Viral penetration into host nucleus" +is_a: GO:0075733 ! intracellular transport of virus +created_by: jl +creation_date: 2009-05-01T02:43:16Z + +[Term] +id: GO:0075733 +name: intracellular transport of virus +namespace: biological_process +alt_id: GO:0046788 +alt_id: GO:0046795 +alt_id: GO:0046796 +def: "The directed movement of a virus, or part of a virus, within the host cell." [GOC:ai, GOC:bf, GOC:jl, PMID:11733033] +synonym: "egress of virus within host cell" EXACT [] +synonym: "intracellular transport of viral material" EXACT [GOC:bf, GOC:jl] +synonym: "intracellular virion transport" RELATED [] +synonym: "movement of virus within host cell" EXACT [] +synonym: "viral egress" RELATED [] +synonym: "viral genome transport in host cell" EXACT [] +is_a: GO:0046794 ! transport of virus +intersection_of: GO:0046794 ! transport of virus +intersection_of: occurs_in GO:0043657 ! host cell +relationship: occurs_in GO:0043657 ! host cell +relationship: part_of GO:0019058 ! viral life cycle +created_by: jl +creation_date: 2009-05-01T04:01:33Z + +[Term] +id: GO:0080001 +name: mucilage extrusion from seed coat +namespace: biological_process +def: "The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat." [PMID:18266922] +synonym: "mucilage release from seed coat" RELATED [] +synonym: "secretion of mucilage from seed coat" RELATED [] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0009845 ! seed germination +relationship: part_of GO:0048316 ! seed development + +[Term] +id: GO:0080002 +name: UDP-glucose:4-aminobenzoate acylglucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP." [EC:2.4.1.-, PMID:18385129] +synonym: "UDP-glucose:p-aminobenzoate acylglucosyltransferase activity" RELATED [] +synonym: "UDP-glucose:p-aminobenzoate glucosyltransferase activity" RELATED [] +synonym: "UDP-glucose:pABA acylglucosyltransferase activity" RELATED [] +xref: MetaCyc:RXN-6142 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080003 +name: thalianol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the triterpene thalianol." [PMID:18356490] +synonym: "thalianol metabolism" EXACT [GOC:tair_curators] +is_a: GO:0010683 ! tricyclic triterpenoid metabolic process + +[Term] +id: GO:0080004 +name: thalian-diol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15." [PMID:18356490] +xref: EC:1.14.21 +xref: MetaCyc:RXN-9637 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0080005 +name: photosystem stoichiometry adjustment +namespace: biological_process +def: "Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis." [PMID:11607105] +is_a: GO:0010109 ! regulation of photosynthesis + +[Term] +id: GO:0080006 +name: internode patterning +namespace: biological_process +def: "Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached." [GOC:tb] +is_a: GO:0007389 ! pattern specification process +relationship: part_of GO:0048367 ! shoot system development + +[Term] +id: GO:0080007 +name: S-nitrosoglutathione reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+." [MetaCyc:RXN-10742, PMID:11260719] +xref: MetaCyc:RXN-10742 +is_a: GO:0016657 ! oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor + +[Term] +id: GO:0080008 +name: Cul4-RING E3 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein." [PMID:16792691, PMID:18223036, PMID:18552200] +is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex + +[Term] +id: GO:0080009 +name: mRNA methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule." [PMID:18505803] +is_a: GO:0001510 ! RNA methylation +is_a: GO:0016556 ! mRNA modification + +[Term] +id: GO:0080010 +name: obsolete regulation of oxygen and reactive oxygen species metabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH)." [PMID:18450450] +comment: This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together. +synonym: "regulation of oxygen and reactive oxygen species metabolic process" EXACT [] +is_obsolete: true +consider: GO:2000374 +consider: GO:2000377 + +[Term] +id: GO:0080011 +name: baruol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol." [MetaCyc:RXN-9685, PMID:17705488] +xref: EC:5.4.99 +xref: MetaCyc:RXN-9685 +is_a: GO:0031559 ! oxidosqualene cyclase activity + +[Term] +id: GO:0080012 +name: trihydroxyferuloyl spermidine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+." [PMID:18557837] +synonym: "N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity" EXACT [MetaCyc:RXN-11263] +xref: MetaCyc:RXN-11263 +is_a: GO:0008171 ! O-methyltransferase activity + +[Term] +id: GO:0080013 +name: (E,E)-geranyllinalool synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate." [MetaCyc:RXN-10441, PMID:18398052] +xref: MetaCyc:RXN-10441 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0080014 +name: thalianol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X." [MetaCyc:RXN-9631, PMID:17474751, PMID:18356490] +comment: In Field and Osbourn 2008 (PMID:18356490), thalianol is referred to as (3S,13S,3R)-malabarica-8,17,21-trien-3-ol and thalian-diol is referred to as (3S,13S,14R)-malabarica-8,17,21-trien-3,?-diol, but the error in this naming system was pointed out in Kolesnikova 2007 (PMID:17474751). The new names used in the definition have been approved by the authors (Field and Osbourn 2008). +xref: EC:1.14.13 +xref: MetaCyc:RXN-9631 +is_a: GO:0004497 ! monooxygenase activity + +[Term] +id: GO:0080015 +name: sabinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate." [MetaCyc:RXN-5103, PMID:12566586, PMID:9747540] +xref: EC:4.2.3 +xref: MetaCyc:RXN-5103 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0010333 ! terpene synthase activity + +[Term] +id: GO:0080016 +name: (-)-E-beta-caryophyllene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate." [MetaCyc:RXN-8414, PMID:12566586, PMID:9442047] +xref: EC:4.2.3 +xref: MetaCyc:RXN-8414 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0080017 +name: alpha-humulene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate." [PMID:12566586, PMID:9442047] +xref: EC:4.2.3 +xref: MetaCyc:RXN-8415 +is_a: GO:0009975 ! cyclase activity +is_a: GO:0010334 ! sesquiterpene synthase activity + +[Term] +id: GO:0080018 +name: anthocyanin 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP." [PMID:15807784] +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080019 +name: fatty-acyl-CoA reductase (alcohol-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA." [PMID:16980563] +synonym: "fatty acyl CoA reductase (alcohol-forming) activity" EXACT [] +synonym: "fatty acyl-CoA reductase (alcohol-forming) activity" EXACT [GOC:mah] +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0080020 +name: regulation of coenzyme A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A." [PMID:18621975] +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015937 ! coenzyme A biosynthetic process +relationship: regulates GO:0015937 ! coenzyme A biosynthetic process + +[Term] +id: GO:0080021 +name: response to benzoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus." [PMID:18753285] +synonym: "response to benzoic acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0080022 +name: primary root development +namespace: biological_process +def: "The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle." [GOC:dhl] +is_a: GO:0048364 ! root development + +[Term] +id: GO:0080023 +name: 3R-hydroxyacyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O." [PMID:16982622] +xref: Reactome:R-HSA-5676637 "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA" +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0080024 +name: indolebutyric acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants." [PMID:18725356] +synonym: "IBA metabolic process" EXACT [] +synonym: "IBA metabolism" EXACT [] +synonym: "indole-3-butyric acid metabolic process" NARROW [] +is_a: GO:0009850 ! auxin metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process + +[Term] +id: GO:0080025 +name: phosphatidylinositol-3,5-bisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions." [GOC:bf, PMID:18397324] +synonym: "PtdIns(3,5)P2 binding" EXACT [] +is_a: GO:1902936 ! phosphatidylinositol bisphosphate binding + +[Term] +id: GO:0080026 +name: response to indolebutyric acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus." [PMID:18725356] +synonym: "response to IBA stimulus" EXACT [] +synonym: "response to indole-3-butyric acid stimulus" NARROW [] +synonym: "response to indolebutyric acid stimulus" EXACT [GOC:dos] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009733 ! response to auxin +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0080027 +name: response to herbivore +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore." [PMID:18987211] +is_a: GO:0051707 ! response to other organism + +[Term] +id: GO:0080028 +name: nitrile biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom." [PMID:18987211] +is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process +is_a: GO:0050898 ! nitrile metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process + +[Term] +id: GO:0080029 +name: cellular response to boron-containing substance levels +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances." [PMID:18952773] +synonym: "cellular response to boron levels" EXACT [] +is_a: GO:0010036 ! response to boron-containing substance +is_a: GO:0031669 ! cellular response to nutrient levels +is_a: GO:0070887 ! cellular response to chemical stimulus + +[Term] +id: GO:0080030 +name: methyl indole-3-acetate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+." [MetaCyc:RXN-10711, PMID:18467465] +synonym: "indole-3-Acetic acid methyl ester esterase activity" EXACT [] +synonym: "MeIAA esterase activity" EXACT [] +synonym: "Methyl IAA esterase activity" EXACT [] +synonym: "methyl indole-3-acetate esterase activity" RELATED [] +xref: EC:3.1.1.1 +xref: MetaCyc:RXN-10711 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0080031 +name: methyl salicylate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+." [MetaCyc:RXNQT-4366, PMID:18467465, PMID:18643994] +synonym: "MESA esterase activity" EXACT [] +synonym: "methyl SA esterase activity" EXACT [] +synonym: "methylsalicylate esterase activity" EXACT [] +synonym: "salicylic acid methyl ester esterase activity" EXACT [] +xref: MetaCyc:RXNQT-4366 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0080032 +name: methyl jasmonate esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol." [PMID:15233793, PMID:18467465] +synonym: "jasmonic acid methyl ester esterase activity" EXACT [] +synonym: "MEJA esterase activity" EXACT [] +synonym: "methyl JA esterase activity" EXACT [] +xref: MetaCyc:RXN-10767 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0080033 +name: response to nitrite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus." [GOC:dhl, PMID:17951451] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound + +[Term] +id: GO:0080034 +name: host response to induction by symbiont of tumor, nodule or growth in host +namespace: biological_process +def: "Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:18836040] +is_a: GO:0009608 ! response to symbiont + +[Term] +id: GO:0080035 +name: 2-hydroxy-but-3-enyl glucosinolate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables." [PMID:11560911, PMID:18945935] +synonym: "2-hydroxy-but-3-enyl glucosinolate anabolism" EXACT [] +synonym: "2-hydroxy-but-3-enyl glucosinolate biosynthesis" EXACT [] +synonym: "2-hydroxy-but-3-enyl glucosinolate formation" EXACT [] +synonym: "2-hydroxy-but-3-enyl glucosinolate synthesis" EXACT [] +synonym: "progoitrin biosynthesis" EXACT [] +synonym: "progoitrin biosynthetic process" EXACT [] +synonym: "progoitrin synthesis" EXACT [] +is_a: GO:0019761 ! glucosinolate biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process + +[Term] +id: GO:0080036 +name: regulation of cytokinin-activated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytokinin signaling." [GOC:dhl] +synonym: "regulation of cytokinin mediated signaling pathway" RELATED [] +synonym: "regulation of cytokinin mediated signalling" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009736 ! cytokinin-activated signaling pathway +relationship: regulates GO:0009736 ! cytokinin-activated signaling pathway + +[Term] +id: GO:0080037 +name: negative regulation of cytokinin-activated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling." [GOC:dhl, PMID:14973166] +synonym: "negative regulation of cytokinin mediated signaling pathway" RELATED [] +synonym: "negative regulation of cytokinin mediated signalling" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0080036 ! regulation of cytokinin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009736 ! cytokinin-activated signaling pathway +relationship: negatively_regulates GO:0009736 ! cytokinin-activated signaling pathway + +[Term] +id: GO:0080038 +name: positive regulation of cytokinin-activated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytokinin signaling." [GOC:dhl] +synonym: "positive regulation of cytokinin mediated signaling pathway" RELATED [] +synonym: "positive regulation of cytokinin mediated signalling" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0080036 ! regulation of cytokinin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009736 ! cytokinin-activated signaling pathway +relationship: positively_regulates GO:0009736 ! cytokinin-activated signaling pathway + +[Term] +id: GO:0080040 +name: positive regulation of cellular response to phosphate starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation." [PMID:18315545] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:0140255 ! regulation of cellular response to phosphate starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016036 ! cellular response to phosphate starvation +relationship: positively_regulates GO:0016036 ! cellular response to phosphate starvation + +[Term] +id: GO:0080041 +name: ADP-ribose pyrophosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate." [GOC:tb] +is_a: GO:0019144 ! ADP-sugar diphosphatase activity + +[Term] +id: GO:0080042 +name: ADP-glucose pyrophosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate." [GOC:tb] +is_a: GO:0019144 ! ADP-sugar diphosphatase activity + +[Term] +id: GO:0080043 +name: quercetin 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule." [PMID:15352060] +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080044 +name: quercetin 7-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule." [PMID:15352060] +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080045 +name: quercetin 3'-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule." [PMID:15352060] +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080046 +name: quercetin 4'-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule." [PMID:15352060] +xref: MetaCyc:RXN-10788 +is_a: GO:0035251 ! UDP-glucosyltransferase activity + +[Term] +id: GO:0080047 +name: GDP-L-galactose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP." [EC:2.7.7.69, PMID:18463094] +xref: EC:2.7.7.69 +xref: MetaCyc:RXNQT-4141 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0080048 +name: GDP-D-glucose phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP." [PMID:18463094] +xref: EC:2.7.7.78 +xref: MetaCyc:RXN-12486 +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity + +[Term] +id: GO:0080049 +name: L-gulono-1,4-lactone dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c." [PMID:18190525] +xref: MetaCyc:RXN-1439 +is_a: GO:0016632 ! oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor + +[Term] +id: GO:0080050 +name: regulation of seed development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of seed development." [PMID:19141706] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048316 ! seed development +relationship: regulates GO:0048316 ! seed development + +[Term] +id: GO:0080051 +name: cutin transport +namespace: biological_process +def: "The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface." [PMID:17951461] +is_a: GO:0071702 ! organic substance transport + +[Term] +id: GO:0080052 +name: response to histidine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus." [PMID:15889294] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0080053 +name: response to phenylalanine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus." [PMID:15889294] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043200 ! response to amino acid + +[Term] +id: GO:0080054 +name: low-affinity nitrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [PMID:19050168] +synonym: "low affinity nitrate transmembrane transporter activity" EXACT [] +is_a: GO:0015112 ! nitrate transmembrane transporter activity + +[Term] +id: GO:0080056 +name: petal vascular tissue pattern formation +namespace: biological_process +def: "Vascular tissue pattern formation as it occurs in the petal of vascular plants." [PMID:17369435] +is_a: GO:0010051 ! xylem and phloem pattern formation +created_by: dhl +creation_date: 2009-04-13T02:25:01Z + +[Term] +id: GO:0080057 +name: sepal vascular tissue pattern formation +namespace: biological_process +def: "Vascular tissue pattern formation as it occurs in the sepal of vascular plants." [PMID:17369435] +is_a: GO:0010051 ! xylem and phloem pattern formation +created_by: dhl +creation_date: 2009-04-13T02:26:19Z + +[Term] +id: GO:0080058 +name: protein deglutathionylation +namespace: biological_process +def: "The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage." [GOC:tb] +synonym: "protein amino acid deglutathionylation" EXACT [GOC:bf] +is_a: GO:0006464 ! cellular protein modification process +created_by: dhl +creation_date: 2009-04-13T02:48:06Z + +[Term] +id: GO:0080059 +name: flavonol 3-O-arabinosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside." [PMID:18757557] +is_a: GO:0008194 ! UDP-glycosyltransferase activity +is_a: GO:0052636 ! arabinosyltransferase activity +created_by: dhl +creation_date: 2009-04-13T02:55:11Z + +[Term] +id: GO:0080060 +name: integument development +namespace: biological_process +def: "The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex." [PMID:19054366, PO:0020021] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009888 ! tissue development +relationship: part_of GO:0048481 ! plant ovule development +created_by: dhl +creation_date: 2009-04-13T02:58:07Z + +[Term] +id: GO:0080061 +name: indole-3-acetonitrile nitrilase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3." [EC:3.5.5.1, MetaCyc:RXN-1404] +is_a: GO:0000257 ! nitrilase activity +created_by: dhl +creation_date: 2009-04-13T03:30:42Z + +[Term] +id: GO:0080062 +name: cytokinin 9-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event." [KEGG_REACTION:R08369, PMID:15342621] +xref: KEGG_REACTION:R08369 +is_a: GO:0035251 ! UDP-glucosyltransferase activity +created_by: dhl +creation_date: 2009-04-13T03:34:38Z + +[Term] +id: GO:0080064 +name: 4,4-dimethyl-9beta,19-cyclopropylsterol oxidation +namespace: biological_process +def: "A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O." [GOC:pr, PMID:14653780] +synonym: "4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity" RELATED [] +is_a: GO:0034440 ! lipid oxidation +created_by: dhl +creation_date: 2009-04-13T03:39:58Z + +[Term] +id: GO:0080065 +name: 4-alpha-methyl-delta7-sterol oxidation +namespace: biological_process +def: "A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O." [GOC:pr, PMID:14653780] +synonym: "4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity" RELATED [] +is_a: GO:0034440 ! lipid oxidation +created_by: dhl +creation_date: 2009-04-13T03:41:50Z + +[Term] +id: GO:0080066 +name: 3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXN-2209 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:04:08Z + +[Term] +id: GO:0080067 +name: 4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXNQT-4329 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:05:53Z + +[Term] +id: GO:0080068 +name: 5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXNQT-4330 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:06:59Z + +[Term] +id: GO:0080069 +name: 7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXNQT-4332 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:07:32Z + +[Term] +id: GO:0080070 +name: 8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXNQT-4333 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:07:58Z + +[Term] +id: GO:0080071 +name: indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate." [PMID:19077143] +xref: MetaCyc:RXN-1443 +is_a: GO:0047364 ! desulfoglucosinolate sulfotransferase activity +created_by: dhl +creation_date: 2009-04-13T04:08:33Z + +[Term] +id: GO:0080072 +name: spermidine:sinapoyl CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule." [PMID:19077165] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dhl +creation_date: 2009-04-13T04:16:28Z + +[Term] +id: GO:0080073 +name: spermidine:coumaroyl CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule." [PMID:19077165] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dhl +creation_date: 2009-04-13T04:16:59Z + +[Term] +id: GO:0080074 +name: spermidine:caffeoyl CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule." [PMID:19077165] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dhl +creation_date: 2009-04-13T04:17:23Z + +[Term] +id: GO:0080075 +name: spermidine:feruloyl CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule." [PMID:19077165] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dhl +creation_date: 2009-04-13T04:17:50Z + +[Term] +id: GO:0080076 +name: caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule." [PMID:19077165] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: dhl +creation_date: 2009-04-14T03:55:49Z + +[Term] +id: GO:0080077 +name: trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule." [PMID:19077165] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: dhl +creation_date: 2009-04-14T04:00:45Z + +[Term] +id: GO:0080078 +name: tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule." [PMID:19077165] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: dhl +creation_date: 2009-04-14T04:01:25Z + +[Term] +id: GO:0080079 +name: cellobiose glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cellobiose + H2O = 2 D-glucose." [PMID:15604686] +synonym: "cellobiose glucohydrolase activity" EXACT [] +xref: MetaCyc:RXN-10773 +is_a: GO:0008422 ! beta-glucosidase activity +created_by: dhl +creation_date: 2009-04-14T04:07:16Z + +[Term] +id: GO:0080081 +name: 4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside." [PMID:15604686] +is_a: GO:0008422 ! beta-glucosidase activity +created_by: dhl +creation_date: 2009-04-14T04:09:06Z + +[Term] +id: GO:0080082 +name: esculin beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of glucosidic link in esculin." [PMID:15604686] +is_a: GO:0008422 ! beta-glucosidase activity +created_by: dhl +creation_date: 2009-04-14T04:09:42Z + +[Term] +id: GO:0080083 +name: beta-gentiobiose beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose." [PMID:15604686] +is_a: GO:0008422 ! beta-glucosidase activity +created_by: dhl +creation_date: 2009-04-14T04:10:14Z + +[Term] +id: GO:0080084 +name: 5S rDNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the 5S rDNA sequence encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists." [PMID:12711688] +is_a: GO:0000182 ! rDNA binding +created_by: dhl +creation_date: 2009-04-22T02:32:20Z + +[Term] +id: GO:0080085 +name: signal recognition particle, chloroplast targeting +namespace: cellular_component +def: "A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast." [PMID:17513500] +is_a: GO:0048500 ! signal recognition particle +created_by: dhl +creation_date: 2009-04-22T02:36:01Z + +[Term] +id: GO:0080086 +name: stamen filament development +namespace: biological_process +def: "The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen." [PMID:19139039, PO:0009067] +synonym: "filament development" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048443 ! stamen development +created_by: dhl +creation_date: 2009-04-22T03:12:03Z + +[Term] +id: GO:0080088 +name: spermidine hydroxycinnamate conjugate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates." [PMID:19077165] +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: dhl +creation_date: 2009-04-22T03:24:03Z + +[Term] +id: GO:0080089 +name: sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative." [PMID:19168716] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: dhl +creation_date: 2009-04-22T03:27:55Z + +[Term] +id: GO:0080090 +name: regulation of primary metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044238 ! primary metabolic process +relationship: regulates GO:0044238 ! primary metabolic process +created_by: dhl +creation_date: 2009-04-22T04:30:52Z + +[Term] +id: GO:0080091 +name: regulation of raffinose metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose." [PMID:19211694] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033530 ! raffinose metabolic process +relationship: regulates GO:0033530 ! raffinose metabolic process +created_by: dhl +creation_date: 2009-04-22T04:36:27Z + +[Term] +id: GO:0080092 +name: regulation of pollen tube growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pollen tube growth." [PMID:19208902] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0051510 ! regulation of unidimensional cell growth +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009860 ! pollen tube growth +relationship: regulates GO:0009860 ! pollen tube growth +created_by: dhl +creation_date: 2009-04-22T04:41:29Z + +[Term] +id: GO:0080093 +name: regulation of photorespiration +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved." [GOC:tb] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009853 ! photorespiration +relationship: regulates GO:0009853 ! photorespiration +created_by: dhl +creation_date: 2009-04-22T04:44:48Z + +[Term] +id: GO:0080094 +name: response to trehalose-6-phosphate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus." [PMID:19193861] +synonym: "response to trehalose-6-phosphate stimulus" EXACT [GOC:dos] +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: dhl +creation_date: 2009-04-22T04:49:13Z + +[Term] +id: GO:0080095 +name: phosphatidylethanolamine-sterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine." [PMID:16020547] +is_a: GO:0008374 ! O-acyltransferase activity +created_by: dhl +creation_date: 2009-04-23T03:39:33Z + +[Term] +id: GO:0080096 +name: phosphatidate-sterol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate." [PMID:16020547] +is_a: GO:0008374 ! O-acyltransferase activity +created_by: dhl +creation_date: 2009-04-23T03:41:42Z + +[Term] +id: GO:0080097 +name: L-tryptophan:pyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine." [MetaCyc:RXN-10139] +comment: This reaction falls within the larger set of reactions associated with EC:2.6.1.28 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.28; note: 3-indole-2-oxopropanoate = indolepyruvate = 3-(indol-3-yl)pyruvate). +xref: EC:2.6.1.28 +xref: MetaCyc:RXN-10139 +xref: RHEA:27587 +is_a: GO:0070529 ! L-tryptophan aminotransferase activity +created_by: dhl +creation_date: 2009-04-23T03:45:23Z + +[Term] +id: GO:0080098 +name: L-tyrosine:pyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine." [MetaCyc:RXN3O-4157] +xref: EC:2.6.1.58 +xref: MetaCyc:RXN3O-4157 +is_a: GO:0070547 ! L-tyrosine aminotransferase activity +created_by: dhl +creation_date: 2009-04-23T03:47:53Z + +[Term] +id: GO:0080099 +name: L-methionine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate." [PMID:18394996] +comment: This reaction falls within the larger set of reactions associated with EC:2.6.1.5 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.5). +synonym: "L-methionine:alpha-ketoglutarate aminotransferase activity" EXACT [] +is_a: GO:0010326 ! methionine-oxo-acid transaminase activity +created_by: dhl +creation_date: 2009-04-23T03:51:20Z + +[Term] +id: GO:0080100 +name: L-glutamine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate." [PMID:18394996] +comment: This reaction falls within the larger set of reactions associated with EC:2.6.1.50 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.50). +synonym: "L-glutamine:alpha-ketoglutarate aminotransferase activity" EXACT [] +xref: EC:2.6.1.50 +is_a: GO:0070548 ! L-glutamine aminotransferase activity +created_by: dhl +creation_date: 2009-04-23T03:56:16Z + +[Term] +id: GO:0080101 +name: phosphatidyl-N-dimethylethanolamine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine." [EC:2.1.1.71, PMID:19366698] +xref: EC:2.1.1.71 +xref: KEGG_REACTION:R01320 +xref: MetaCyc:RXN4FS-2 +is_a: GO:0008170 ! N-methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: dhl +creation_date: 2009-04-23T04:02:41Z + +[Term] +id: GO:0080102 +name: 3-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +xref: MetaCyc:RXN-2221 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:26:41Z + +[Term] +id: GO:0080103 +name: 4-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:27:45Z + +[Term] +id: GO:0080104 +name: 5-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:28:25Z + +[Term] +id: GO:0080105 +name: 6-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:28:55Z + +[Term] +id: GO:0080106 +name: 7-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:29:37Z + +[Term] +id: GO:0080107 +name: 8-methylthiopropyl glucosinolate S-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate." [PMID:18799661] +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: dhl +creation_date: 2009-04-23T04:30:08Z + +[Term] +id: GO:0080108 +name: S-alkylthiohydroximate lyase activity +namespace: molecular_function +def: "Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate." [PMID:14871316] +synonym: "S-alkylthiohydroximate C-S lyase activity" NARROW [] +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: dhl +creation_date: 2009-04-23T04:35:14Z + +[Term] +id: GO:0080109 +name: indole-3-acetonitrile nitrile hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide." [EC:4.2.1.84, MetaCyc:RXN-7567, PMID:11607511, PMID:12430025] +xref: EC:4.2.1.84 +xref: KEGG_REACTION:R04020 +xref: MetaCyc:RXN-7567 +is_a: GO:0018822 ! nitrile hydratase activity +created_by: dhl +creation_date: 2009-04-23T04:37:57Z + +[Term] +id: GO:0080110 +name: sporopollenin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer." [PMID:19218397] +synonym: "sporopollenin biosynthesis" EXACT [] +is_a: GO:0019438 ! aromatic compound biosynthetic process +relationship: part_of GO:0010584 ! pollen exine formation +created_by: dhl +creation_date: 2009-04-23T04:44:16Z + +[Term] +id: GO:0080111 +name: DNA demethylation +namespace: biological_process +def: "The removal of a methyl group from one or more nucleotides within an DNA molecule." [PMID:17208187] +is_a: GO:0035510 ! DNA dealkylation +is_a: GO:0044728 ! DNA methylation or demethylation +is_a: GO:0070988 ! demethylation +created_by: dhl +creation_date: 2009-04-27T02:42:05Z + +[Term] +id: GO:0080112 +name: seed growth +namespace: biological_process +def: "The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo." [GOC:dhl, PO:0009010] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0048316 ! seed development +created_by: dhl +creation_date: 2009-04-27T02:52:07Z + +[Term] +id: GO:0080113 +name: regulation of seed growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of growth of the seed of an plant." [PMID:19141706] +synonym: "regulation of seed size" EXACT [] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0080050 ! regulation of seed development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080112 ! seed growth +relationship: regulates GO:0080112 ! seed growth +created_by: dhl +creation_date: 2009-04-27T02:55:01Z + +[Term] +id: GO:0080114 +name: positive regulation of glycine hydroxymethyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine." [EC:2.1.2.1, PMID:19223513] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051347 ! positive regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004372 ! glycine hydroxymethyltransferase activity +relationship: positively_regulates GO:0004372 ! glycine hydroxymethyltransferase activity +created_by: dhl +creation_date: 2009-04-27T03:27:15Z + +[Term] +id: GO:0080115 +name: myosin XI tail binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the tail region of a myosin XI heavy chain." [PMID:18703495] +is_a: GO:0032029 ! myosin tail binding +created_by: dhl +creation_date: 2009-04-27T03:31:45Z + +[Term] +id: GO:0080116 +name: glucuronoxylan glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule." [PMID:18980649] +is_a: GO:0015020 ! glucuronosyltransferase activity +created_by: dhl +creation_date: 2009-04-27T03:33:49Z + +[Term] +id: GO:0080117 +name: secondary growth +namespace: biological_process +def: "Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium." [ISBN:0471245208, PMID:19074290, PO:0005598, PO:0025004] +comment: Occurs in vascular plants, including gymnosperms and most dicotyledons. Commonly supplemented by activity of the cork cambium or phellogen (PO:0005599). Monocotyledons do not have secondary growth, but may undergo primary thickening (GO:0080192) or secondary thickening (GO:0080191), which can give the appearance of secondary growth. Primary and secondary growth can occur simultaneously in the same organism. +synonym: "cambial secondary growth" EXACT [] +is_a: GO:0080190 ! lateral growth +created_by: dhl +creation_date: 2009-04-27T03:36:28Z + +[Term] +id: GO:0080118 +name: brassinosteroid sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative." [PMID:10409637, PMID:17039368] +is_a: GO:0008146 ! sulfotransferase activity +created_by: dhl +creation_date: 2009-04-27T03:39:36Z + +[Term] +id: GO:0080119 +name: ER body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species." [PMID:18780803, PMID:19147648] +synonym: "endoplasmic reticulum body organization" EXACT [] +synonym: "endoplasmic reticulum body organization and biogenesis" RELATED [GOC:mah] +synonym: "ER body organisation" EXACT [GOC:mah] +synonym: "ER body organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0006996 ! organelle organization +created_by: dhl +creation_date: 2009-04-27T04:01:26Z + +[Term] +id: GO:0080120 +name: CAAX-box protein maturation +namespace: biological_process +def: "A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase." [PMID:12039957, PMID:17114793, PMID:18641086] +synonym: "CAAX-box protein processing" RELATED [] +synonym: "farnesylated protein maturation" RELATED [GOC:vw] +is_a: GO:0044267 ! cellular protein metabolic process +is_a: GO:0051604 ! protein maturation +relationship: has_part GO:0016485 ! protein processing +relationship: has_part GO:0018342 ! protein prenylation +created_by: dhl +creation_date: 2009-04-28T03:06:13Z + +[Term] +id: GO:0080121 +name: AMP transport +namespace: biological_process +def: "The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [PMID:18923018] +synonym: "adenosine monophosphate transport" EXACT [] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051503 ! adenine nucleotide transport +created_by: dhl +creation_date: 2009-04-28T04:01:37Z + +[Term] +id: GO:0080122 +name: AMP transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other." [PMID:18923018] +synonym: "adenosine monophosphate transmembrane transporter activity" EXACT [] +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +relationship: part_of GO:0080121 ! AMP transport +created_by: dhl +creation_date: 2009-04-28T04:05:39Z + +[Term] +id: GO:0080123 +name: jasmonate-amino synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate)." [PMID:15258265, PMID:17291501] +synonym: "ja-amino synthetase activity" EXACT [] +synonym: "jasmonate-amido synthetase activity" EXACT [] +synonym: "jasmonate-amino acid conjugate synthetase activity" EXACT [] +synonym: "jasmonate-amino acid synthetase activity" EXACT [] +synonym: "jasmonate:amino acid synthetase activity" EXACT [] +synonym: "jasmonic acid-amino synthetase activity" EXACT [] +synonym: "jasmonyl-amino synthetase activity" EXACT [] +is_a: GO:0016881 ! acid-amino acid ligase activity +created_by: dhl +creation_date: 2009-04-28T04:08:35Z + +[Term] +id: GO:0080124 +name: pheophytinase activity +namespace: molecular_function +def: "Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide." [PMID:19304936] +synonym: "pheophytin pheophorbide hydrolase activity" EXACT [] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: dhl +creation_date: 2009-04-28T04:16:11Z + +[Term] +id: GO:0080125 +name: obsolete multicellular structure septum development +namespace: biological_process +def: "OBSOLETE. The process whose specific outcome is the progression of the multicellular structure septum over time, from its formation to the mature structure. The multicellular structure septum is the thin partition or membrane that divides a cavity or a mass of tissue." [GOC:dhl] +comment: This term was made obsolete because it is not a useful grouping term. +is_obsolete: true +created_by: dhl +creation_date: 2009-04-28T04:31:14Z + +[Term] +id: GO:0080126 +name: ovary septum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)." [PMID:17855426] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:1905328 ! plant septum development +relationship: part_of GO:0035670 ! plant-type ovary development +created_by: dhl +creation_date: 2009-04-28T04:34:39Z + +[Term] +id: GO:0080127 +name: fruit septum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit." [GOC:dhl, PO:0005008] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009791 ! post-embryonic development +is_a: GO:1905328 ! plant septum development +relationship: part_of GO:0010154 ! fruit development +created_by: dhl +creation_date: 2009-04-28T04:37:19Z + +[Term] +id: GO:0080128 +name: anther septum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone." [GOC:dhl, PO:0005010] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:1905328 ! plant septum development +relationship: part_of GO:0048653 ! anther development +created_by: dhl +creation_date: 2009-04-28T04:41:16Z + +[Term] +id: GO:0080129 +name: proteasome core complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles." [PMID:12401807, PMID:17971041] +synonym: "20S proteasome assembly" EXACT [] +is_a: GO:0043248 ! proteasome assembly +created_by: dhl +creation_date: 2009-04-29T03:34:50Z + +[Term] +id: GO:0080130 +name: L-phenylalanine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate." [GOC:pmn_curators, PMID:18394996] +comment: This reaction falls within the larger set of reactions associated with EC:2.6.1.57 and several other EC numbers (See BRENDA:http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.57). +synonym: "L-phenylalanine:alpha-ketoglutarate aminotransferase activity" EXACT [] +xref: EC:2.6.1.57 +xref: KEGG_REACTION:R00694 +xref: MetaCyc:PHEAMINOTRANS-RXN +xref: MetaCyc:RXN-10814 +xref: RHEA:25152 +is_a: GO:0008793 ! aromatic-amino-acid:2-oxoglutarate aminotransferase activity +is_a: GO:0070546 ! L-phenylalanine aminotransferase activity +created_by: dhl +creation_date: 2009-04-29T03:42:47Z + +[Term] +id: GO:0080131 +name: hydroxyjasmonate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate." [EC:2.8.2.-, GOC:pmn_curators, MetaCyc:RXN-10451, MetaCyc:RXN-10453, PMID:12637544] +synonym: "11-hydroxyjasmonate sulfotransferase activity" NARROW [MetaCyc:RXN-10453] +synonym: "11-hydroxyjasmonic acid sulfotransferase activity" NARROW [MetaCyc:RXN-10453] +synonym: "11-OHJA sulfotransferase activity" NARROW [MetaCyc:RXN-10453] +synonym: "12-hydroxyjasmonate sulfotransferase activity" NARROW [MetaCyc:RXN-10451] +synonym: "12-hydroxyjasmonic acid sulfotransferase activity" NARROW [MetaCyc:RXN-10451] +synonym: "12-OHJA sulfotransferase activity" NARROW [MetaCyc:RXN-10451] +synonym: "hydroxyjasmonic acid sulfotransferase activity" EXACT [] +synonym: "OHJA sulfotransferase activity" EXACT [] +is_a: GO:0008146 ! sulfotransferase activity +created_by: dhl +creation_date: 2009-04-29T03:47:12Z + +[Term] +id: GO:0080132 +name: fatty acid alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain." [PMID:19054355] +synonym: "fatty acid 2-hydroxylase" EXACT [] +xref: Reactome:R-HSA-5693761 "FA2H hydroxylates CERA" +is_a: GO:0016491 ! oxidoreductase activity +created_by: dhl +creation_date: 2009-05-06T04:43:36Z + +[Term] +id: GO:0080133 +name: midchain alkane hydroxylase activity +namespace: molecular_function +def: "Catalysis of the conversion of an alkane to a secondary alcohol." [PMID:17905869] +is_a: GO:0016713 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen +created_by: dhl +creation_date: 2009-05-06T04:46:17Z + +[Term] +id: GO:0080134 +name: regulation of response to stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006950 ! response to stress +relationship: regulates GO:0006950 ! response to stress +created_by: dhl +creation_date: 2009-05-06T04:51:28Z + +[Term] +id: GO:0080135 +name: regulation of cellular response to stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033554 ! cellular response to stress +relationship: regulates GO:0033554 ! cellular response to stress +created_by: dhl +creation_date: 2009-05-06T05:02:52Z + +[Term] +id: GO:0080136 +name: priming of cellular response to stress +namespace: biological_process +def: "The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress." [PMID:19318610] +synonym: "priming of response to stress" BROAD [] +synonym: "priming of stress response" BROAD [] +is_a: GO:0080135 ! regulation of cellular response to stress +relationship: part_of GO:0033554 ! cellular response to stress +created_by: dhl +creation_date: 2009-05-06T05:05:15Z + +[Term] +id: GO:0080139 +name: borate efflux transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane." [PMID:18603465] +synonym: "boron efflux transmembrane transporter activity" RELATED [] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +is_a: GO:0015562 ! efflux transmembrane transporter activity +relationship: part_of GO:0035445 ! borate transmembrane transport +created_by: dhl +creation_date: 2009-05-19T04:11:45Z + +[Term] +id: GO:0080140 +name: regulation of jasmonic acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid." [GOC:dhl] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009694 ! jasmonic acid metabolic process +relationship: regulates GO:0009694 ! jasmonic acid metabolic process +created_by: dhl +creation_date: 2009-05-19T04:24:55Z + +[Term] +id: GO:0080141 +name: regulation of jasmonic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid." [GOC:dhl] +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0080140 ! regulation of jasmonic acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009695 ! jasmonic acid biosynthetic process +relationship: regulates GO:0009695 ! jasmonic acid biosynthetic process +created_by: dhl +creation_date: 2009-05-19T04:28:39Z + +[Term] +id: GO:0080142 +name: regulation of salicylic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid." [GOC:dhl] +is_a: GO:0010337 ! regulation of salicylic acid metabolic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009697 ! salicylic acid biosynthetic process +relationship: regulates GO:0009697 ! salicylic acid biosynthetic process +created_by: dhl +creation_date: 2009-05-19T04:38:23Z + +[Term] +id: GO:0080143 +name: regulation of amino acid export +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle." [PMID:20018597] +is_a: GO:1903789 ! regulation of amino acid transmembrane transport +relationship: regulates GO:0032973 ! amino acid export across plasma membrane +created_by: dhl +creation_date: 2010-01-20T04:43:56Z + +[Term] +id: GO:0080144 +name: amino acid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell." [PMID:19955263] +is_a: GO:0055081 ! anion homeostasis +created_by: dhl +creation_date: 2010-01-27T04:47:27Z + +[Term] +id: GO:0080145 +name: cysteine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell." [PMID:19955263] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: dhl +creation_date: 2010-01-27T04:49:14Z + +[Term] +id: GO:0080146 +name: L-cysteine desulfhydrase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+." [MetaCyc:LCYSDESULF-RXN, PMID:19955263] +xref: EC:4.4.1.1 +xref: MetaCyc:LCYSDESULF-RXN +xref: Reactome:R-HSA-1614591 "Excess cysteine yields lanthionine and H2S" +xref: Reactome:R-HSA-1614614 "Cysteine is degraded to serine and H2S" +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: dhl +creation_date: 2010-01-27T04:50:43Z + +[Term] +id: GO:0080147 +name: root hair cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state." [PMID:19675148] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0048765 ! root hair cell differentiation +created_by: dhl +creation_date: 2010-03-26T01:45:08Z + +[Term] +id: GO:0080148 +name: negative regulation of response to water deprivation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." [PMID:18835996] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2000070 ! regulation of response to water deprivation +relationship: negatively_regulates GO:0009414 ! response to water deprivation +created_by: dhl +creation_date: 2010-03-26T01:58:11Z + +[Term] +id: GO:0080149 +name: sucrose induced translational repression +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level." [PMID:19403731] +synonym: "negative regulation of translation in response to sucrose" EXACT [] +is_a: GO:0032055 ! negative regulation of translation in response to stress +created_by: dhl +creation_date: 2010-03-26T04:13:15Z + +[Term] +id: GO:0080150 +name: S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine." [MetaCyc:RXN-6722, PMID:10852939] +synonym: "S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity" EXACT [] +xref: MetaCyc:RXN-6722 +is_a: GO:0008171 ! O-methyltransferase activity +created_by: dhl +creation_date: 2010-03-26T04:19:39Z + +[Term] +id: GO:0080151 +name: positive regulation of salicylic acid mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction." [PMID:20181750] +synonym: "positive regulation of salicylic acid mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:2000031 ! regulation of salicylic acid mediated signaling pathway +is_a: GO:2001040 ! positive regulation of cellular response to drug +relationship: positively_regulates GO:0009863 ! salicylic acid mediated signaling pathway +created_by: dhl +creation_date: 2010-05-20T03:10:46Z + +[Term] +id: GO:0080152 +name: regulation of reductive pentose-phosphate cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle." [PMID:17031544] +synonym: "regulation of C3 photosynthesis" NARROW [] +synonym: "regulation of Calvin cycle" NARROW [] +is_a: GO:0010110 ! regulation of photosynthesis, dark reaction +relationship: regulates GO:0019253 ! reductive pentose-phosphate cycle +created_by: dhl +creation_date: 2010-07-01T02:49:55Z + +[Term] +id: GO:0080153 +name: negative regulation of reductive pentose-phosphate cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle." [PMID:17031544, PMID:20399532] +synonym: "negative regulation of C3 photosynthesis" NARROW [] +synonym: "negative regulation of Calvin cycle" NARROW [] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:0080152 ! regulation of reductive pentose-phosphate cycle +is_a: GO:1905156 ! negative regulation of photosynthesis +relationship: negatively_regulates GO:0019253 ! reductive pentose-phosphate cycle +created_by: dhl +creation_date: 2010-07-01T02:55:27Z + +[Term] +id: GO:0080154 +name: regulation of fertilization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009566 ! fertilization +relationship: regulates GO:0009566 ! fertilization +created_by: dhl +creation_date: 2010-09-01T03:44:27Z + +[Term] +id: GO:0080155 +name: regulation of double fertilization forming a zygote and endosperm +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana." [GOC:DHL, PMID:20478994] +is_a: GO:0080154 ! regulation of fertilization +relationship: regulates GO:0009567 ! double fertilization forming a zygote and endosperm +created_by: dhl +creation_date: 2010-09-01T03:46:39Z + +[Term] +id: GO:0080156 +name: mitochondrial mRNA modification +namespace: biological_process +def: "The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically." [PMID:20566637] +synonym: "mitochondrial mRNA editing" NARROW [] +synonym: "mitochondrial RNA editing" BROAD [] +is_a: GO:0016556 ! mRNA modification +is_a: GO:1900864 ! mitochondrial RNA modification +intersection_of: GO:0016556 ! mRNA modification +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: dhl +creation_date: 2010-09-01T03:55:48Z + +[Term] +id: GO:0080157 +name: regulation of plant-type cell wall organization or biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall." [PMID:20530756] +synonym: "regulation of plant-type cell wall organisation or biogenesis" EXACT [GOC:mah] +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +relationship: regulates GO:0071669 ! plant-type cell wall organization or biogenesis +created_by: dhl +creation_date: 2010-09-01T04:02:37Z + +[Term] +id: GO:0080158 +name: obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis +namespace: biological_process +def: "OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex." [PMID:20561259] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true +created_by: dhl +creation_date: 2010-09-01T04:05:55Z + +[Term] +id: GO:0080159 +name: zygote elongation +namespace: biological_process +def: "The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana." [GOC:tb] +is_a: GO:0009826 ! unidimensional cell growth +is_a: GO:0048598 ! embryonic morphogenesis +created_by: dhl +creation_date: 2010-09-01T04:07:51Z + +[Term] +id: GO:0080160 +name: selenate transport +namespace: biological_process +def: "The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [PMID:18761637] +is_a: GO:0015698 ! inorganic anion transport +created_by: dhl +creation_date: 2010-09-01T04:17:38Z + +[Term] +id: GO:0080161 +name: auxin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth." [PMID:19506555] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0060918 ! auxin transport +created_by: dhl +creation_date: 2010-09-23T03:37:43Z + +[Term] +id: GO:0080162 +name: intracellular auxin transport +namespace: biological_process +def: "The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth." [PMID:19506555] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0060919 ! auxin influx +intersection_of: GO:0060918 ! auxin transport +intersection_of: occurs_in GO:0005622 ! intracellular +created_by: dhl +creation_date: 2010-09-23T03:46:29Z + +[Term] +id: GO:0080163 +name: regulation of protein serine/threonine phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate." [PMID:19407142] +synonym: "regulation of protein phosphatase type 2c activity" NARROW [] +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +relationship: regulates GO:0004722 ! protein serine/threonine phosphatase activity +created_by: dhl +creation_date: 2010-09-23T03:51:37Z + +[Term] +id: GO:0080164 +name: regulation of nitric oxide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:DHL] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +relationship: regulates GO:0046209 ! nitric oxide metabolic process +created_by: dhl +creation_date: 2010-09-23T04:02:50Z + +[Term] +id: GO:0080165 +name: callose deposition in phloem sieve plate +namespace: biological_process +def: "Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls." [PMID:19470642] +is_a: GO:0052545 ! callose localization +created_by: dhl +creation_date: 2010-09-23T04:12:49Z + +[Term] +id: GO:0080166 +name: stomium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released." [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048653 ! anther development +created_by: dhl +creation_date: 2010-09-23T05:03:40Z + +[Term] +id: GO:0080167 +name: response to karrikin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants)." [PMID:20351290] +is_a: GO:0009628 ! response to abiotic stimulus +created_by: dhl +creation_date: 2010-09-23T05:07:22Z + +[Term] +id: GO:0080168 +name: abscisic acid transport +namespace: biological_process +def: "The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore." [PMID:20133881] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0046865 ! terpenoid transport +created_by: dhl +creation_date: 2010-09-23T05:08:56Z + +[Term] +id: GO:0080169 +name: cellular response to boron-containing substance deprivation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances." [PMID:20059736] +synonym: "cellular response to boron deprivation" EXACT [] +synonym: "cellular response to boron starvation" EXACT [] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0062197 ! cellular response to chemical stress +is_a: GO:0080029 ! cellular response to boron-containing substance levels +created_by: dhl +creation_date: 2010-09-23T05:10:00Z + +[Term] +id: GO:0080170 +name: hydrogen peroxide transmembrane transport +namespace: biological_process +def: "The process in which hydrogen peroxide is transported across a membrane." [GOC:tb] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "hydrogen peroxide membrane transport" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0051181 ! cofactor transport +created_by: dhl +creation_date: 2010-09-23T05:12:14Z + +[Term] +id: GO:0080171 +name: lytic vacuole organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole." [PMID:20729380] +synonym: "lytic vacuolar assembly" NARROW [] +synonym: "lytic vacuole biogenesis" RELATED [] +synonym: "lytic vacuole organisation" EXACT [] +synonym: "lytic vacuole organization and biogenesis" RELATED [] +is_a: GO:0007033 ! vacuole organization +created_by: dhl +creation_date: 2011-04-25T04:40:46Z + +[Term] +id: GO:0080172 +name: petal epidermis patterning +namespace: biological_process +def: "The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis." [GOC:tb] +is_a: GO:0003002 ! regionalization +created_by: dhl +creation_date: 2011-04-25T04:44:06Z + +[Term] +id: GO:0080173 +name: male-female gamete recognition during double fertilization forming a zygote and endosperm +namespace: biological_process +def: "The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana." [PMID:21123745] +synonym: "gamete recognition" BROAD [] +synonym: "male-female gamete recognition" EXACT [] +is_a: GO:0009988 ! cell-cell recognition +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0061936 ! fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm +created_by: dhl +creation_date: 2011-04-26T04:58:58Z + +[Term] +id: GO:0080175 +name: phragmoplast microtubule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells." [PMID:19383896] +synonym: "phragmoplast microtubule cytoskeleton organization" EXACT [] +synonym: "phragmoplast microtubule organisation" EXACT [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: occurs_in GO:0009524 ! phragmoplast +relationship: occurs_in GO:0009524 ! phragmoplast +created_by: dhl +creation_date: 2011-04-28T03:54:11Z + +[Term] +id: GO:0080176 +name: xyloglucan 1,6-alpha-xylosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus." [PMID:20801759] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: dhl +creation_date: 2011-04-28T04:08:39Z + +[Term] +id: GO:0080177 +name: plastoglobule organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids." [PMID:20813909] +synonym: "plastoglobule organisation" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0009658 ! chloroplast organization +created_by: dhl +creation_date: 2011-04-28T04:13:07Z + +[Term] +id: GO:0080178 +name: 5-carbamoylmethyl uridine residue modification +namespace: biological_process +def: "The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA." [GOC:dph, GOC:tb] +synonym: "5-carbamoylmethyluridine metabolic process" RELATED [] +is_a: GO:0030488 ! tRNA methylation +created_by: dhl +creation_date: 2011-04-28T04:36:23Z + +[Term] +id: GO:0080179 +name: 1-methylguanosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-methylguanosine." [GOC:tb] +is_a: GO:1901068 ! guanosine-containing compound metabolic process +created_by: dhl +creation_date: 2011-04-28T04:38:13Z + +[Term] +id: GO:0080180 +name: 2-methylguanosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-methylguanosine." [GOC:tb] +is_a: GO:1901068 ! guanosine-containing compound metabolic process +created_by: dhl +creation_date: 2011-04-28T04:41:01Z + +[Term] +id: GO:0080181 +name: lateral root branching +namespace: biological_process +def: "Any process involved in the formation of branches in lateral roots." [GOC:tb] +is_a: GO:0001763 ! morphogenesis of a branching structure +relationship: part_of GO:0010102 ! lateral root morphogenesis +created_by: dhl +creation_date: 2011-08-10T04:13:33Z + +[Term] +id: GO:0080182 +name: histone H3-K4 trimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone." [GOC:BHF, GOC:se, GOC:tb] +is_a: GO:0018023 ! peptidyl-lysine trimethylation +is_a: GO:0051568 ! histone H3-K4 methylation +created_by: dhl +creation_date: 2011-08-10T04:18:36Z + +[Term] +id: GO:0080183 +name: response to photooxidative stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [DOI:10.1111/j.1399-3054.1994.tb03042.x] +is_a: GO:0006979 ! response to oxidative stress +created_by: dhl +creation_date: 2011-08-10T04:26:11Z + +[Term] +id: GO:0080184 +name: response to phenylpropanoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin." [GOC:tb] +is_a: GO:0014070 ! response to organic cyclic compound +created_by: dhl +creation_date: 2011-08-10T04:28:21Z + +[Term] +id: GO:0080185 +name: effector-mediated induction of plant hypersensitive response by symbiont +namespace: biological_process +alt_id: GO:0052101 +alt_id: GO:0052286 +alt_id: GO:0052423 +alt_id: GO:0052527 +def: "A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes)." [PMID:16497589, PMID:22241993, PMID:23411798, PMID:27641772, Wikipedia:Effector-triggered_immunity] +synonym: "activation by organism of defense response in host by specific elicitors" BROAD [] +synonym: "activation by organism of host gene-for-gene resistance" EXACT [] +synonym: "activation by organism of host resistance gene-dependent defense response" EXACT [] +synonym: "activation by symbiont of host resistance gene-dependent defense response" EXACT [] +synonym: "avirulence protein" RELATED [] +synonym: "effector-triggered immunity" RELATED [] +synonym: "effector-triggered induction of host innate immune response" RELATED [] +synonym: "effector-triggered induction of plant hypersensitive response by symbiont" RELATED [] +synonym: "effector-triggered necrosis" RELATED [PMID:27641772] +synonym: "ETI triggered of host innate immune response" RELATED [] +synonym: "ETI-triggered of host innate immune response" RELATED [] +synonym: "induction by organism of defense response in host by specific elicitors" BROAD [] +synonym: "induction by organism of host gene-for-gene resistance" EXACT [] +synonym: "induction by organism of pathogen-race/host plant cultivar-specific resistance in host" BROAD [] +synonym: "induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction" BROAD [] +synonym: "induction by symbiont of host resistance gene-dependent defense response" EXACT [] +synonym: "induction of effector-triggered immunity (ETI)" RELATED [] +synonym: "positive regulation by organism of defense response in host by specific elicitors" BROAD [] +synonym: "positive regulation by organism of host gene-for-gene resistance" EXACT [] +synonym: "positive regulation by symbiont of host resistance gene-dependent defense response" RELATED [] +is_a: GO:0034053 ! modulation by symbiont of host defense-related programmed cell death +is_a: GO:0052042 ! positive regulation by symbiont of host programmed cell death +is_a: GO:0052158 ! modulation by symbiont of host resistance gene-dependent defense response +is_a: GO:0052390 ! induction by symbiont of host innate immune response +is_a: GO:0140404 ! effector-mediated modulation of host innate immune response by symbiont +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18694 xsd:anyURI +created_by: dhl +creation_date: 2011-08-10T04:33:53Z + +[Term] +id: GO:0080186 +name: developmental vegetative growth +namespace: biological_process +def: "The increase in size or mass of non-reproductive plant parts." [PO:0007134] +is_a: GO:0048589 ! developmental growth +created_by: dhl +creation_date: 2011-08-17T03:45:53Z + +[Term] +id: GO:0080187 +name: floral organ senescence +namespace: biological_process +def: "An organ senescence that has as a participant a floral organ." [PMID:21689171, PO:0025395] +comment: Includes senescence of petals, sepals, anthers, and any other plant organ that is part of a flower. Floral organ senescence may follow pollination. In some flowers, the organs of the corolla abscise before they senesce. +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0090693 ! plant organ senescence +relationship: part_of GO:0048437 ! floral organ development +created_by: dhl +creation_date: 2012-03-09T04:08:50Z + +[Term] +id: GO:0080188 +name: gene silencing by RNA-directed DNA methylation +namespace: biological_process +def: "An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci." [PMID:21420348] +synonym: "RdDM" EXACT [] +synonym: "RNA-directed DNA methylation" RELATED [] +is_a: GO:0140458 ! pre-transcriptional gene silencing by RNA +relationship: has_part GO:0006306 ! DNA methylation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19328 xsd:anyURI +created_by: dhl +creation_date: 2012-05-22T02:22:50Z + +[Term] +id: GO:0080189 +name: primary growth +namespace: biological_process +def: "Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed." [ISBN:0471245208] +comment: Has its inception in the apical meristems (PO:0020144) and continues in their derivative meristems - protoderm (PO:0006210) and procambium (PO:0025275) - even in older tissues. Primary and secondary growth can occur simultaneously in the same organism. +is_a: GO:0032501 ! multicellular organismal process +is_a: GO:0040007 ! growth +created_by: dhl +creation_date: 2012-12-06T15:20:41Z + +[Term] +id: GO:0080190 +name: lateral growth +namespace: biological_process +def: "Growth of a plant axis (shoot axis or root) that originates from a lateral meristem." [PO:0020145] +comment: Includes thickening of plant axes (PO:0025004) due to the activity of a cambium (PO:0005597), known as secondary growth and found in most gymnosperms and dicotyledons, a primary thickening meristem (PO:0005039) as found in many monocotyledons, some ferns and some cycads, or secondary thickening meristem, (PO:0025414) as found in some monocotyledons. +is_a: GO:0040007 ! growth +created_by: dhl +creation_date: 2012-12-06T15:42:28Z + +[Term] +id: GO:0080191 +name: secondary thickening +namespace: biological_process +def: "Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem." [JSTOR:4354165, PO:0025004, PO:0025414] +comment: Occurs in shoot axes in some monocotyledons such as Dracaena, and rarely in roots of monocotyledons. Distinct from primary thickening, because it is distant from and generally discontinuous with the apical meristem. +is_a: GO:0080190 ! lateral growth +created_by: dhl +creation_date: 2012-12-06T15:50:33Z + +[Term] +id: GO:0080192 +name: primary thickening +namespace: biological_process +def: "Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem." [ISBN:0471245208, JSTOR:4354165, PO:0005039, PO:0025004] +comment: Occurs in shoot axes and rarely in roots in many monocotyledons. +is_a: GO:0080190 ! lateral growth +created_by: dhl +creation_date: 2012-12-06T15:55:18Z + +[Term] +id: GO:0080193 +name: diffuse secondary thickening +namespace: biological_process +def: "Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem." [GOC:dhl] +comment: Occurs in the stems (PO:0009047) of some Arecaceae (palms). +is_a: GO:0080190 ! lateral growth +created_by: dhl +creation_date: 2012-12-06T15:57:50Z + +[Term] +id: GO:0085000 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:08:54Z + +[Term] +id: GO:0085001 +name: formation by symbiont of stylet for nutrient acquisition from host +namespace: biological_process +def: "The assembly by a symbiont of a stylet, a hollow protrusible spear-like structure projected into the host cell for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +is_a: GO:0052093 ! formation of specialized structure for nutrient acquisition from host +created_by: jl +creation_date: 2010-02-24T01:49:06Z + +[Term] +id: GO:0085002 +name: obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T02:38:10Z + +[Term] +id: GO:0085003 +name: obsolete interaction with host via secreted substance released from stylet +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T02:53:56Z + +[Term] +id: GO:0085004 +name: obsolete interaction with host via secreted substance released from haustorium +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T02:58:39Z + +[Term] +id: GO:0085005 +name: obsolete interaction with host via secreted substance released from invasive hyphae +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T02:59:51Z + +[Term] +id: GO:0085006 +name: obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:00:56Z + +[Term] +id: GO:0085007 +name: obsolete interaction with host via secreted substance released from rhoptry +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secreaton system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:02:08Z + +[Term] +id: GO:0085008 +name: obsolete interaction with host via secreted substance released from microneme +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:03:16Z + +[Term] +id: GO:0085009 +name: obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with host mediated by symbiont secreted substance released from Maurers cleft" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:08:39Z + +[Term] +id: GO:0085010 +name: obsolete interaction with host mediated by secreted substance entering host via endocytosis +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:12:31Z + +[Term] +id: GO:0085011 +name: obsolete interaction with host via protein secreted by Sec complex +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with host via protein secreted by Sec secretion system" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:18:36Z + +[Term] +id: GO:0085012 +name: obsolete interaction with host via protein secreted by Tat complex +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "interaction with host via protein secreted by Tat secretion system" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:29:37Z + +[Term] +id: GO:0085013 +name: obsolete interaction with host via protein secreted by type VII secretion system +namespace: biological_process +def: "OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-02-10T03:31:07Z + +[Term] +id: GO:0085014 +name: dormancy entry of symbiont in host +namespace: biological_process +def: "Entry into a dormant state of the symbiont within the host organism." [GOC:jl] +is_a: GO:0022611 ! dormancy process +is_a: GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2010-05-19T02:33:26Z + +[Term] +id: GO:0085015 +name: dormancy maintenance of symbiont in host +namespace: biological_process +def: "Any process in which a dormant state is maintained by the symbiont within the host organism." [GOC:jl] +synonym: "non-replicating persistence" EXACT [] +synonym: "NRP" EXACT [] +is_a: GO:0022611 ! dormancy process +is_a: GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2010-05-19T03:17:32Z + +[Term] +id: GO:0085016 +name: dormancy exit of symbiont in host +namespace: biological_process +def: "Exit from dormant state, also known as resuscitation, of the symbiont within the host organism." [GOC:jl] +synonym: "resuscitation of symbiont" EXACT [] +is_a: GO:0022611 ! dormancy process +is_a: GO:0044114 ! development of symbiont in host +created_by: jl +creation_date: 2010-05-19T03:23:07Z + +[Term] +id: GO:0085017 +name: entry into host cell by a symbiont-containing vacuole +namespace: biological_process +alt_id: GO:0052370 +def: "The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole." [GOC:jl, PMID:18665841, PMID:8690024, PMID:9580555] +synonym: "symbiont entry into host cell forming a parasitophorous vacuole" EXACT [] +synonym: "symbiont entry into host cell forming a pathogen-containing vacuole" EXACT [] +synonym: "symbiont entry into host cell forming a symbiont-containing vacuole" RELATED [] +is_a: GO:0044409 ! entry into host +created_by: jl +creation_date: 2010-05-20T02:55:34Z + +[Term] +id: GO:0085018 +name: maintenance of symbiont-containing vacuole by host +namespace: biological_process +def: "The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment." [GOC:jl, GOC:yaf, PMID:18665841] +synonym: "maintenance of parasitophorous vacuole" EXACT [] +synonym: "maintenance of pathogen-containing vacuole" EXACT [] +synonym: "maintenance of vacuolar integrity during bacterial infection" NARROW [] +is_a: GO:0051851 ! modulation by host of symbiont process +created_by: jl +creation_date: 2010-05-20T03:58:51Z + +[Term] +id: GO:0085019 +name: formation by symbiont of a tubovesicular network for nutrient acquisition from host +namespace: biological_process +def: "The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "formation of a symbiont- induced tubovesicular network for nutrient acquisition from host" EXACT [] +is_a: GO:0052093 ! formation of specialized structure for nutrient acquisition from host +created_by: jl +creation_date: 2010-05-20T04:29:24Z + +[Term] +id: GO:0085020 +name: protein K6-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair." [GOC:sp] +synonym: "protein K6-linked polyubiquitination" EXACT [GOC:mah] +is_a: GO:0000209 ! protein polyubiquitination +created_by: jl +creation_date: 2010-06-01T03:05:03Z + +[Term] +id: GO:0085021 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:20:44Z + +[Term] +id: GO:0085022 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:32:02Z + +[Term] +id: GO:0085023 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system +namespace: biological_process +def: "OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:35:02Z + +[Term] +id: GO:0085024 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex +namespace: biological_process +def: "OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:44:31Z + +[Term] +id: GO:0085025 +name: obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex +namespace: biological_process +def: "OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +comment: This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target. +synonym: "modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system" EXACT [] +is_obsolete: true +created_by: jl +creation_date: 2010-07-09T03:47:01Z + +[Term] +id: GO:0085026 +name: tubovesicular membrane network +namespace: cellular_component +def: "A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains." [GOC:pamgo_curators] +synonym: "TVM network" EXACT [] +synonym: "TVN" EXACT [] +is_a: GO:0033655 ! host cell cytoplasm part +is_a: GO:0043264 ! extracellular non-membrane-bounded organelle +created_by: jl +creation_date: 2010-07-09T03:55:41Z + +[Term] +id: GO:0085029 +name: extracellular matrix assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0030198 ! extracellular matrix organization +created_by: jl +creation_date: 2010-07-14T12:52:49Z + +[Term] +id: GO:0085030 +name: symbiotic process benefiting host +namespace: biological_process +def: "A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism." [GOC:pdt] +synonym: "mutualism" RELATED [] +is_a: GO:0044403 ! symbiotic process +created_by: jl +creation_date: 2010-07-27T01:25:21Z + +[Term] +id: GO:0085032 +name: modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade +namespace: biological_process +def: "Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "modulation by symbiont of host NF-kappaB-mediated signal transduction pathway" EXACT [] +is_a: GO:0043122 ! regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:0052027 ! modulation by symbiont of host signal transduction pathway +created_by: jl +creation_date: 2010-07-27T02:13:37Z + +[Term] +id: GO:0085033 +name: induction by symbiont of host I-kappaB kinase/NF-kappaB cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "activation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "induction by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway" EXACT [] +synonym: "positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway" EXACT [] +synonym: "stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +synonym: "upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +is_a: GO:0043123 ! positive regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:0085032 ! modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade +created_by: jl +creation_date: 2010-07-27T02:47:01Z + +[Term] +id: GO:0085034 +name: suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] +synonym: "negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade" EXACT [] +is_a: GO:0043124 ! negative regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:0052029 ! suppression by symbiont of host signal transduction pathway +created_by: jl +creation_date: 2010-07-27T03:32:44Z + +[Term] +id: GO:0085035 +name: haustorium +namespace: cellular_component +def: "A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane." [GOC:pamgo_curators] +comment: See also: extrahaustorial matrix ; GO:0085036 and extrahaustorial membrane ; GO:0085037. +is_a: GO:0042995 ! cell projection +created_by: jl +creation_date: 2010-07-27T03:42:24Z + +[Term] +id: GO:0085036 +name: extrahaustorial matrix +namespace: cellular_component +def: "The space between the symbiont plasma membrane and the extrahaustorial membrane of the host." [GOC:pamgo_curators] +comment: See also: haustorium ; GO:0085035 and extrahaustorial membrane ; GO:0085037. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005576 ! extracellular region +relationship: part_of GO:0043655 ! host extracellular space +created_by: jl +creation_date: 2010-07-27T03:58:20Z + +[Term] +id: GO:0085037 +name: extrahaustorial membrane +namespace: cellular_component +def: "The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane." [GOC:pamgo_curators] +comment: See also: haustorium ; GO:0085035 and extrahaustorial matrix ; GO:0085036. +is_a: GO:0033644 ! host cell membrane +relationship: part_of GO:0020002 ! host cell plasma membrane +created_by: jl +creation_date: 2010-07-27T04:00:49Z + +[Term] +id: GO:0085039 +name: hyphal membrane +namespace: cellular_component +def: "A host-derived membrane surrounding the symbiont hypha during infection." [GOC:pamgo_curators] +synonym: "extra-invasive hyphal membrane" RELATED [] +is_a: GO:0033644 ! host cell membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +created_by: jl +creation_date: 2010-07-27T04:19:46Z + +[Term] +id: GO:0085040 +name: obsolete extra-invasive hyphal space +namespace: cellular_component +def: "OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane." [GOC:pamgo_curators] +comment: This term was obsoleted because the cellular component represented is not different from 'host cytoplasm'. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19013 xsd:anyURI +is_obsolete: true +created_by: jl +creation_date: 2010-07-27T04:21:26Z + +[Term] +id: GO:0085041 +name: arbuscule +namespace: cellular_component +def: "Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange." [GOC:pamgo_curators] +comment: See also: periarbuscular membrane ; GO:0085042. +is_a: GO:0085035 ! haustorium +created_by: jl +creation_date: 2010-07-27T04:29:03Z + +[Term] +id: GO:0085042 +name: periarbuscular membrane +namespace: cellular_component +def: "A host-derived membrane surrounding the symbiont arbuscule during symbiosis." [GOC:pamgo_curators] +comment: See also: arbuscule ; GO:0085041. +is_a: GO:0033644 ! host cell membrane +created_by: jl +creation_date: 2010-07-27T04:31:37Z + +[Term] +id: GO:0085044 +name: disassembly by symbiont of host cuticle +namespace: biological_process +def: "The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:jl, GOC:pamgo_curators] +synonym: "catabolism of host cuticle" EXACT [] +synonym: "degradation of host cuticle" RELATED [] +is_a: GO:0052111 ! modification by symbiont of host structure +created_by: jl +creation_date: 2010-07-27T01:08:15Z + +[Term] +id: GO:0086001 +name: cardiac muscle cell action potential +namespace: biological_process +def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0001508 ! action potential +created_by: tb +creation_date: 2011-11-10T07:45:11Z + +[Term] +id: GO:0086002 +name: cardiac muscle cell action potential involved in contraction +namespace: biological_process +def: "An action potential that occurs in a cardiac muscle cell and is involved in its contraction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086001 ! cardiac muscle cell action potential +intersection_of: GO:0086001 ! cardiac muscle cell action potential +intersection_of: part_of GO:0086003 ! cardiac muscle cell contraction +relationship: part_of GO:0086003 ! cardiac muscle cell contraction +created_by: tb +creation_date: 2011-11-10T07:45:11Z + +[Term] +id: GO:0086003 +name: cardiac muscle cell contraction +namespace: biological_process +def: "The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0070252 ! actin-mediated cell contraction +relationship: part_of GO:0060048 ! cardiac muscle contraction +created_by: tb +creation_date: 2011-11-10T07:48:15Z + +[Term] +id: GO:0086004 +name: regulation of cardiac muscle cell contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0055117 ! regulation of cardiac muscle contraction +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086003 ! cardiac muscle cell contraction +relationship: regulates GO:0086003 ! cardiac muscle cell contraction +created_by: tb +creation_date: 2011-11-10T07:49:10Z + +[Term] +id: GO:0086005 +name: ventricular cardiac muscle cell action potential +namespace: biological_process +def: "An action potential that occurs in a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086002 ! cardiac muscle cell action potential involved in contraction +created_by: tb +creation_date: 2011-11-10T07:59:36Z + +[Term] +id: GO:0086006 +name: voltage-gated sodium channel activity involved in cardiac muscle cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: part_of GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +relationship: part_of GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:34:49Z + +[Term] +id: GO:0086007 +name: voltage-gated calcium channel activity involved in cardiac muscle cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +relationship: part_of GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:04:42Z + +[Term] +id: GO:0086008 +name: voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005249 ! voltage-gated potassium channel activity +intersection_of: GO:0005249 ! voltage-gated potassium channel activity +intersection_of: part_of GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +relationship: part_of GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:38:09Z + +[Term] +id: GO:0086009 +name: membrane repolarization +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0034220 ! ion transmembrane transport +is_a: GO:0042391 ! regulation of membrane potential +created_by: tb +creation_date: 2011-11-10T08:13:18Z + +[Term] +id: GO:0086010 +name: membrane depolarization during action potential +namespace: biological_process +def: "The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0051899 ! membrane depolarization +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0001508 ! action potential +relationship: part_of GO:0001508 ! action potential +created_by: tb +creation_date: 2011-11-10T08:15:05Z + +[Term] +id: GO:0086011 +name: membrane repolarization during action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086009 ! membrane repolarization +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0001508 ! action potential +relationship: part_of GO:0001508 ! action potential +created_by: tb +creation_date: 2011-11-10T08:15:05Z + +[Term] +id: GO:0086012 +name: membrane depolarization during cardiac muscle cell action potential +namespace: biological_process +def: "The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086010 ! membrane depolarization during action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086001 ! cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:20:33Z + +[Term] +id: GO:0086013 +name: membrane repolarization during cardiac muscle cell action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086011 ! membrane repolarization during action potential +is_a: GO:0099622 ! cardiac muscle cell membrane repolarization +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086001 ! cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:23:25Z + +[Term] +id: GO:0086014 +name: atrial cardiac muscle cell action potential +namespace: biological_process +def: "An action potential that occurs in an atrial cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086002 ! cardiac muscle cell action potential involved in contraction +relationship: part_of GO:0086026 ! atrial cardiac muscle cell to AV node cell signaling +created_by: tb +creation_date: 2011-11-10T08:49:13Z + +[Term] +id: GO:0086015 +name: SA node cell action potential +namespace: biological_process +def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "SA node cardiac muscle cell action potential" EXACT [] +synonym: "SAN cardiac muscle cell action potential" EXACT [] +synonym: "sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086018 ! SA node cell to atrial cardiac muscle cell signaling +created_by: tb +creation_date: 2011-11-10T08:50:15Z + +[Term] +id: GO:0086016 +name: AV node cell action potential +namespace: biological_process +def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086027 ! AV node cell to bundle of His cell signaling +created_by: tb +creation_date: 2011-11-10T08:58:56Z + +[Term] +id: GO:0086017 +name: Purkinje myocyte action potential +namespace: biological_process +def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086029 ! Purkinje myocyte to ventricular cardiac muscle cell signaling +created_by: tb +creation_date: 2011-11-10T08:58:56Z + +[Term] +id: GO:0086018 +name: SA node cell to atrial cardiac muscle cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT [] +synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] +synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] +synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] +synonym: "sinus node cardiomyocyte to atrial cardiomyocyte signalling" NARROW [] +is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction +is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication +created_by: tb +creation_date: 2011-11-10T09:15:01Z + +[Term] +id: GO:0086019 +name: cell-cell signaling involved in cardiac conduction +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah] +is_a: GO:0007267 ! cell-cell signaling +is_a: GO:0086065 ! cell communication involved in cardiac conduction +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: part_of GO:0061337 ! cardiac conduction +created_by: dph +creation_date: 2011-11-16T03:43:52Z + +[Term] +id: GO:0086020 +name: gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling" EXACT [] +synonym: "gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling" EXACT [] +synonym: "gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling" EXACT [] +synonym: "gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling" NARROW [] +is_a: GO:0086075 ! gap junction channel activity involved in cardiac conduction electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086021 ! SA node cell to atrial cardiac muscle cell communication by electrical coupling +relationship: part_of GO:0086021 ! SA node cell to atrial cardiac muscle cell communication by electrical coupling +created_by: tb +creation_date: 2011-11-11T02:08:19Z + +[Term] +id: GO:0086021 +name: SA node cell to atrial cardiac muscle cell communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication by electrical coupling" EXACT [] +synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling" EXACT [] +synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication by electrical coupling" EXACT [] +synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling" EXACT [] +synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling" NARROW [] +is_a: GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication +created_by: tb +creation_date: 2011-11-10T09:20:39Z + +[Term] +id: GO:0086022 +name: SA node cell-atrial cardiac muscle cell adhesion involved in cell communication +namespace: biological_process +def: "The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "SA cardiac muscle cell-atrial cardiac muscle cell adhesion involved in cell communication" EXACT [] +synonym: "SA cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication" EXACT [] +synonym: "SAN cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication" EXACT [] +synonym: "sinoatrial node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication" EXACT [] +synonym: "sinus node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication" NARROW [] +is_a: GO:0034113 ! heterotypic cell-cell adhesion +is_a: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +relationship: part_of GO:0086070 ! SA node cell to atrial cardiac muscle cell communication +created_by: tb +creation_date: 2011-11-10T09:26:52Z + +[Term] +id: GO:0086023 +name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "adrenergic receptor signaling pathway involved in heart process" EXACT [] +synonym: "adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:bf] +synonym: "beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:bf] +is_a: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +is_a: GO:0086103 ! G protein-coupled receptor signaling pathway involved in heart process +intersection_of: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: tb +creation_date: 2011-11-11T02:51:03Z + +[Term] +id: GO:0086024 +name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate +namespace: biological_process +def: "An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate." [GOC:bf, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21099118] +synonym: "activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:mtg_cardiac_conduct_nov11] +synonym: "adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:mtg_cardiac_conduct_nov11] +synonym: "adrenergic receptor signaling pathway involved in positive regulation of heart rate" BROAD [] +synonym: "adrenergic receptor signalling pathway involved in positive regulation of heart rate" BROAD [GOC:bf] +synonym: "beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:mtg_cardiac_conduct_nov11] +synonym: "Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:mtg_cardiac_conduct_nov11] +synonym: "If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0001996 ! positive regulation of heart rate by epinephrine-norepinephrine +is_a: GO:0140200 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate +intersection_of: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +intersection_of: part_of GO:0010460 ! positive regulation of heart rate +relationship: part_of GO:0010460 ! positive regulation of heart rate +created_by: tb +creation_date: 2011-11-10T09:38:49Z + +[Term] +id: GO:0086026 +name: atrial cardiac muscle cell to AV node cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrial cardiomyocyte to atrioventricular node cell signaling" EXACT [] +synonym: "atrial cardiomyocyte to AV node cell signaling" EXACT [] +synonym: "atrial cardiomyocyte to AV node cell signalling" EXACT [GOC:mah] +is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction +is_a: GO:0086066 ! atrial cardiac muscle cell to AV node cell communication +created_by: tb +creation_date: 2011-11-11T02:02:14Z + +[Term] +id: GO:0086027 +name: AV node cell to bundle of His cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrioventricular node to bundle of His cell signaling" EXACT [] +synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah] +is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction +is_a: GO:0086067 ! AV node cell to bundle of His cell communication +created_by: tb +creation_date: 2011-11-11T02:02:14Z + +[Term] +id: GO:0086028 +name: bundle of His cell to Purkinje myocyte signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "bundle of His cardiac muscle cell to Purkinje myocyte signaling" EXACT [] +synonym: "bundle of His cardiac muscle cell to Purkinje myocyte signalling" EXACT [GOC:mah] +is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction +is_a: GO:0086069 ! bundle of His cell to Purkinje myocyte communication +created_by: tb +creation_date: 2011-11-11T02:02:14Z + +[Term] +id: GO:0086029 +name: Purkinje myocyte to ventricular cardiac muscle cell signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah] +is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction +is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication +created_by: tb +creation_date: 2011-11-11T02:02:14Z + +[Term] +id: GO:0086030 +name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation +namespace: biological_process +def: "An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10571541] +synonym: "adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation" EXACT [GOC:mtg_cardiac_conduct_nov11] +synonym: "adrenergic receptor signaling pathway involved in cardiac muscle relaxation" EXACT [] +synonym: "adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC" RELATED [GOC:mtg_cardiac_conduct_nov11] +synonym: "adrenergic receptor-induced cardiac relaxation" RELATED [PMID:10571541] +synonym: "Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation" EXACT [GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +intersection_of: part_of GO:0055119 ! relaxation of cardiac muscle +relationship: part_of GO:0055119 ! relaxation of cardiac muscle +created_by: tb +creation_date: 2011-11-11T02:53:24Z + +[Term] +id: GO:0086033 +name: G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +namespace: biological_process +def: "A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, Wikipedia:G_protein-gated_ion_channel] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate" EXACT [] +synonym: "M2 receptor signalling pathway involved in negative regulation of heart rate" EXACT [] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate" EXACT [] +synonym: "muscarinic receptor signalling pathway involved in negative regulation of heart rate" EXACT [] +is_a: GO:0086093 ! G protein-coupled acetylcholine receptor signaling pathway involved in heart process +intersection_of: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway +intersection_of: part_of GO:0010459 ! negative regulation of heart rate +relationship: part_of GO:0003063 ! negative regulation of heart rate by acetylcholine +created_by: tb +creation_date: 2011-11-11T03:11:58Z + +[Term] +id: GO:0086036 +name: regulation of cardiac muscle cell membrane potential +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0042391 ! regulation of membrane potential +created_by: tb +creation_date: 2011-11-11T03:23:36Z + +[Term] +id: GO:0086037 +name: sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005391 ! sodium:potassium-exchanging ATPase activity +intersection_of: GO:0005391 ! sodium:potassium-exchanging ATPase activity +intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +created_by: tb +creation_date: 2011-11-11T03:33:44Z + +[Term] +id: GO:0086038 +name: calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005432 ! calcium:sodium antiporter activity +intersection_of: GO:0005432 ! calcium:sodium antiporter activity +intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +created_by: tb +creation_date: 2011-11-11T03:33:44Z + +[Term] +id: GO:0086039 +name: calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +created_by: tb +creation_date: 2011-11-11T03:33:44Z + +[Term] +id: GO:0086040 +name: sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential" EXACT [] +is_a: GO:0015385 ! sodium:proton antiporter activity +intersection_of: GO:0015385 ! sodium:proton antiporter activity +intersection_of: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +relationship: part_of GO:0086036 ! regulation of cardiac muscle cell membrane potential +created_by: tb +creation_date: 2011-11-11T03:33:44Z + +[Term] +id: GO:0086041 +name: voltage-gated potassium channel activity involved in SA node cell action potential depolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated potassium channel activity involved in SAN cell action potential depolarization" EXACT [] +synonym: "voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization" EXACT [] +synonym: "voltage-gated potassium channel activity involved in sinus node cell action potential depolarization" NARROW [] +is_a: GO:0005249 ! voltage-gated potassium channel activity +intersection_of: GO:0005267 ! potassium channel activity +intersection_of: part_of GO:0086046 ! membrane depolarization during SA node cell action potential +relationship: part_of GO:0086046 ! membrane depolarization during SA node cell action potential +created_by: tb +creation_date: 2011-11-11T03:37:42Z + +[Term] +id: GO:0086042 +name: cardiac muscle cell-cardiac muscle cell adhesion +namespace: biological_process +def: "The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "cardiomyocyte-cardiomyocyte adhesion" EXACT [] +is_a: GO:0034109 ! homotypic cell-cell adhesion +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: tb +creation_date: 2011-11-11T04:06:25Z + +[Term] +id: GO:0086043 +name: bundle of His cell action potential +namespace: biological_process +def: "An action potential that occurs in a bundle of His cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086028 ! bundle of His cell to Purkinje myocyte signaling +created_by: dph +creation_date: 2011-11-15T12:01:18Z + +[Term] +id: GO:0086044 +name: atrial cardiac muscle cell to AV node cell communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrial cardiomyocyte to atrioventricular node cell communication by electrical coupling" EXACT [] +synonym: "atrial cardiomyocyte to AV node cell communication by electrical coupling" EXACT [] +is_a: GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +is_a: GO:0086066 ! atrial cardiac muscle cell to AV node cell communication +created_by: dph +creation_date: 2011-11-15T02:51:29Z + +[Term] +id: GO:0086045 +name: membrane depolarization during AV node cell action potential +namespace: biological_process +def: "The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "membrane depolarization during AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086016 ! AV node cell action potential +relationship: part_of GO:0086016 ! AV node cell action potential +created_by: dph +creation_date: 2011-11-16T10:45:18Z + +[Term] +id: GO:0086046 +name: membrane depolarization during SA node cell action potential +namespace: biological_process +def: "The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane depolarization involved in regulation of SA node cardiac muscle cell action potential" EXACT [] +synonym: "membrane depolarization involved in regulation of SAN cardiac muscle cell action potential" EXACT [] +synonym: "membrane depolarization involved in regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "membrane depolarization involved in regulation of sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086015 ! SA node cell action potential +relationship: part_of GO:0086015 ! SA node cell action potential +created_by: dph +creation_date: 2011-11-16T10:52:57Z + +[Term] +id: GO:0086047 +name: membrane depolarization during Purkinje myocyte cell action potential +namespace: biological_process +def: "The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086017 ! Purkinje myocyte action potential +relationship: part_of GO:0086017 ! Purkinje myocyte action potential +created_by: dph +creation_date: 2011-11-16T10:54:47Z + +[Term] +id: GO:0086048 +name: membrane depolarization during bundle of His cell action potential +namespace: biological_process +def: "The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane depolarization during bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086043 ! bundle of His cell action potential +relationship: part_of GO:0086043 ! bundle of His cell action potential +created_by: dph +creation_date: 2011-11-16T10:56:26Z + +[Term] +id: GO:0086049 +name: membrane repolarization during AV node cell action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane repolarization involved in regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "membrane repolarization involved in regulation of AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086016 ! AV node cell action potential +relationship: part_of GO:0086016 ! AV node cell action potential +created_by: dph +creation_date: 2011-11-16T11:43:38Z + +[Term] +id: GO:0086050 +name: membrane repolarization during bundle of His cell action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane repolarization during bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086043 ! bundle of His cell action potential +relationship: part_of GO:0086043 ! bundle of His cell action potential +created_by: dph +creation_date: 2011-11-16T11:50:41Z + +[Term] +id: GO:0086051 +name: membrane repolarization during Purkinje myocyte action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086017 ! Purkinje myocyte action potential +relationship: part_of GO:0086017 ! Purkinje myocyte action potential +created_by: dph +creation_date: 2011-11-16T11:51:56Z + +[Term] +id: GO:0086052 +name: membrane repolarization during SA node cell action potential +namespace: biological_process +def: "The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11] +synonym: "membrane repolarization involved in regulation of SA node cardiac muscle cell action potential" EXACT [] +synonym: "membrane repolarization involved in regulation of SAN cardiac muscle cell action potential" EXACT [] +synonym: "membrane repolarization involved in regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "membrane repolarization involved in regulation of sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086015 ! SA node cell action potential +relationship: part_of GO:0086015 ! SA node cell action potential +created_by: dph +creation_date: 2011-11-16T11:54:12Z + +[Term] +id: GO:0086053 +name: AV node cell to bundle of His cell communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrioventricular node cell to bundle of His cell communication by electrical coupling" EXACT [] +is_a: GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +is_a: GO:0086067 ! AV node cell to bundle of His cell communication +created_by: dph +creation_date: 2011-11-16T12:31:08Z + +[Term] +id: GO:0086054 +name: bundle of His cell to Purkinje myocyte communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "bundle of His cardiac muscle cell to Purkinje myocyte communication by electrical coupling" EXACT [] +is_a: GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +is_a: GO:0086069 ! bundle of His cell to Purkinje myocyte communication +created_by: dph +creation_date: 2011-11-17T10:46:43Z + +[Term] +id: GO:0086055 +name: Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling +namespace: biological_process +def: "The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication +created_by: dph +creation_date: 2011-11-17T10:51:59Z + +[Term] +id: GO:0086056 +name: voltage-gated calcium channel activity involved in AV node cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0086007 ! voltage-gated calcium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0086016 ! AV node cell action potential +relationship: part_of GO:0086045 ! membrane depolarization during AV node cell action potential +created_by: dph +creation_date: 2011-11-17T12:24:22Z + +[Term] +id: GO:0086057 +name: voltage-gated calcium channel activity involved in bundle of His cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0086007 ! voltage-gated calcium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0086043 ! bundle of His cell action potential +relationship: part_of GO:0086048 ! membrane depolarization during bundle of His cell action potential +created_by: dph +creation_date: 2011-11-17T12:32:51Z + +[Term] +id: GO:0086058 +name: voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086007 ! voltage-gated calcium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0086017 ! Purkinje myocyte action potential +relationship: part_of GO:0086047 ! membrane depolarization during Purkinje myocyte cell action potential +created_by: dph +creation_date: 2011-11-17T12:35:02Z + +[Term] +id: GO:0086059 +name: voltage-gated calcium channel activity involved SA node cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0086007 ! voltage-gated calcium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0086015 ! SA node cell action potential +relationship: part_of GO:0086046 ! membrane depolarization during SA node cell action potential +created_by: dph +creation_date: 2011-11-17T12:39:27Z + +[Term] +id: GO:0086060 +name: voltage-gated sodium channel activity involved in AV node cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0086006 ! voltage-gated sodium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: part_of GO:0086016 ! AV node cell action potential +relationship: part_of GO:0086045 ! membrane depolarization during AV node cell action potential +created_by: dph +creation_date: 2011-11-17T12:52:48Z + +[Term] +id: GO:0086061 +name: voltage-gated sodium channel activity involved in bundle of His cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0086006 ! voltage-gated sodium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: part_of GO:0086043 ! bundle of His cell action potential +relationship: part_of GO:0086048 ! membrane depolarization during bundle of His cell action potential +created_by: dph +creation_date: 2011-11-17T12:58:13Z + +[Term] +id: GO:0086062 +name: voltage-gated sodium channel activity involved in Purkinje myocyte action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086006 ! voltage-gated sodium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: part_of GO:0086017 ! Purkinje myocyte action potential +relationship: part_of GO:0086047 ! membrane depolarization during Purkinje myocyte cell action potential +created_by: dph +creation_date: 2011-11-17T01:50:43Z + +[Term] +id: GO:0086063 +name: voltage-gated sodium channel activity involved in SA node cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0086006 ! voltage-gated sodium channel activity involved in cardiac muscle cell action potential +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: part_of GO:0086015 ! SA node cell action potential +relationship: part_of GO:0086046 ! membrane depolarization during SA node cell action potential +created_by: dph +creation_date: 2011-11-17T01:53:08Z + +[Term] +id: GO:0086064 +name: cell communication by electrical coupling involved in cardiac conduction +namespace: biological_process +def: "The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0010644 ! cell communication by electrical coupling +is_a: GO:0086065 ! cell communication involved in cardiac conduction +intersection_of: GO:0010644 ! cell communication by electrical coupling +intersection_of: part_of GO:0061337 ! cardiac conduction +created_by: dph +creation_date: 2011-11-22T08:49:44Z + +[Term] +id: GO:0086065 +name: cell communication involved in cardiac conduction +namespace: biological_process +def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0007154 ! cell communication +intersection_of: GO:0007154 ! cell communication +intersection_of: part_of GO:0061337 ! cardiac conduction +relationship: part_of GO:0061337 ! cardiac conduction +created_by: dph +creation_date: 2011-11-22T08:57:02Z + +[Term] +id: GO:0086066 +name: atrial cardiac muscle cell to AV node cell communication +namespace: biological_process +def: "The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrial cardiomyocyte to atrioventricular node cell communication" EXACT [] +synonym: "atrial cardiomyocyte to AV node cell communication" EXACT [] +is_a: GO:0086065 ! cell communication involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T09:05:09Z + +[Term] +id: GO:0086067 +name: AV node cell to bundle of His cell communication +namespace: biological_process +def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrioventricular node cell to bundle of His cell communication" EXACT [] +is_a: GO:0086065 ! cell communication involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T09:11:44Z + +[Term] +id: GO:0086068 +name: Purkinje myocyte to ventricular cardiac muscle cell communication +namespace: biological_process +def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086065 ! cell communication involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T09:14:49Z + +[Term] +id: GO:0086069 +name: bundle of His cell to Purkinje myocyte communication +namespace: biological_process +def: "The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "bundle of His cardiac muscle cell to Purkinje myocyte communication" EXACT [] +is_a: GO:0086065 ! cell communication involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T09:18:49Z + +[Term] +id: GO:0086070 +name: SA node cell to atrial cardiac muscle cell communication +namespace: biological_process +def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT [] +synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] +synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT [] +synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] +synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication" NARROW [] +is_a: GO:0086065 ! cell communication involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T09:32:45Z + +[Term] +id: GO:0086071 +name: atrial cardiac muscle cell-AV node cell adhesion involved in cell communication +namespace: biological_process +def: "The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrial cardiomyocyte-atrioventricular node cell adhesion involved in cell communication" EXACT [] +synonym: "atrial cardiomyocyte-AV node cell adhesion involved in cell communication" EXACT [] +is_a: GO:0034113 ! heterotypic cell-cell adhesion +is_a: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +intersection_of: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +intersection_of: part_of GO:0086066 ! atrial cardiac muscle cell to AV node cell communication +relationship: part_of GO:0086066 ! atrial cardiac muscle cell to AV node cell communication +created_by: dph +creation_date: 2011-11-22T09:46:33Z + +[Term] +id: GO:0086072 +name: AV node cell-bundle of His cell adhesion involved in cell communication +namespace: biological_process +def: "The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "atrioventricular node cell-bundle of His cell adhesion involved in cell communication" EXACT [] +is_a: GO:0034113 ! heterotypic cell-cell adhesion +is_a: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +relationship: part_of GO:0086067 ! AV node cell to bundle of His cell communication +created_by: dph +creation_date: 2011-11-22T09:49:59Z + +[Term] +id: GO:0086073 +name: bundle of His cell-Purkinje myocyte adhesion involved in cell communication +namespace: biological_process +def: "The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0034113 ! heterotypic cell-cell adhesion +is_a: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +relationship: part_of GO:0086069 ! bundle of His cell to Purkinje myocyte communication +created_by: dph +creation_date: 2011-11-22T10:00:30Z + +[Term] +id: GO:0086074 +name: Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication +namespace: biological_process +def: "The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0034113 ! heterotypic cell-cell adhesion +is_a: GO:0086042 ! cardiac muscle cell-cardiac muscle cell adhesion +relationship: part_of GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication +created_by: dph +creation_date: 2011-11-22T10:02:24Z + +[Term] +id: GO:0086075 +name: gap junction channel activity involved in cardiac conduction electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:1903763 ! gap junction channel activity involved in cell communication by electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +relationship: part_of GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +created_by: dph +creation_date: 2011-11-22T10:08:29Z + +[Term] +id: GO:0086076 +name: gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling" EXACT [] +synonym: "gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling" RELATED [] +is_a: GO:0086075 ! gap junction channel activity involved in cardiac conduction electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086044 ! atrial cardiac muscle cell to AV node cell communication by electrical coupling +relationship: part_of GO:0086044 ! atrial cardiac muscle cell to AV node cell communication by electrical coupling +created_by: dph +creation_date: 2011-11-22T10:26:27Z + +[Term] +id: GO:0086077 +name: gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling" EXACT [] +is_a: GO:0086075 ! gap junction channel activity involved in cardiac conduction electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086053 ! AV node cell to bundle of His cell communication by electrical coupling +relationship: part_of GO:0086053 ! AV node cell to bundle of His cell communication by electrical coupling +created_by: dph +creation_date: 2011-11-22T10:29:53Z + +[Term] +id: GO:0086078 +name: gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086075 ! gap junction channel activity involved in cardiac conduction electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086054 ! bundle of His cell to Purkinje myocyte communication by electrical coupling +relationship: part_of GO:0086054 ! bundle of His cell to Purkinje myocyte communication by electrical coupling +created_by: dph +creation_date: 2011-11-22T10:34:13Z + +[Term] +id: GO:0086079 +name: gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling +namespace: molecular_function +def: "A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086075 ! gap junction channel activity involved in cardiac conduction electrical coupling +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0086055 ! Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling +relationship: part_of GO:0086055 ! Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling +created_by: dph +creation_date: 2011-11-22T10:36:23Z + +[Term] +id: GO:0086080 +name: protein binding involved in heterotypic cell-cell adhesion +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0098632 ! cell-cell adhesion mediator activity +intersection_of: GO:0005515 ! protein binding +intersection_of: part_of GO:0034113 ! heterotypic cell-cell adhesion +relationship: part_of GO:0034113 ! heterotypic cell-cell adhesion +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: dph +creation_date: 2011-11-22T10:53:52Z + +[Term] +id: GO:0086081 +name: cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication" EXACT [] +synonym: "cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication" EXACT [] +is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: part_of GO:0086071 ! atrial cardiac muscle cell-AV node cell adhesion involved in cell communication +relationship: part_of GO:0086071 ! atrial cardiac muscle cell-AV node cell adhesion involved in cell communication +created_by: dph +creation_date: 2011-11-22T11:00:47Z + +[Term] +id: GO:0086082 +name: cell adhesive protein binding involved in AV node cell-bundle of His cell communication +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication" EXACT [] +is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: part_of GO:0086072 ! AV node cell-bundle of His cell adhesion involved in cell communication +relationship: part_of GO:0086072 ! AV node cell-bundle of His cell adhesion involved in cell communication +created_by: dph +creation_date: 2011-11-22T11:09:37Z + +[Term] +id: GO:0086083 +name: cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: part_of GO:0086073 ! bundle of His cell-Purkinje myocyte adhesion involved in cell communication +relationship: part_of GO:0086073 ! bundle of His cell-Purkinje myocyte adhesion involved in cell communication +created_by: dph +creation_date: 2011-11-22T11:11:03Z + +[Term] +id: GO:0086084 +name: cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: part_of GO:0086074 ! Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication +relationship: part_of GO:0086074 ! Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication +created_by: dph +creation_date: 2011-11-22T11:13:16Z + +[Term] +id: GO:0086085 +name: cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication" EXACT [] +is_a: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion +intersection_of: part_of GO:0086022 ! SA node cell-atrial cardiac muscle cell adhesion involved in cell communication +relationship: part_of GO:0086022 ! SA node cell-atrial cardiac muscle cell adhesion involved in cell communication +created_by: dph +creation_date: 2011-11-22T11:15:07Z + +[Term] +id: GO:0086086 +name: voltage-gated potassium channel activity involved in AV node cell action potential repolarization +namespace: molecular_function +def: "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization" EXACT [] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0086049 ! membrane repolarization during AV node cell action potential +created_by: dph +creation_date: 2011-11-22T01:26:32Z + +[Term] +id: GO:0086087 +name: voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0086050 ! membrane repolarization during bundle of His cell action potential +created_by: dph +creation_date: 2011-11-22T01:30:20Z + +[Term] +id: GO:0086088 +name: voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0086051 ! membrane repolarization during Purkinje myocyte action potential +created_by: dph +creation_date: 2011-11-22T01:32:02Z + +[Term] +id: GO:0086089 +name: voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0086014 ! atrial cardiac muscle cell action potential +created_by: dph +creation_date: 2011-11-22T01:33:01Z + +[Term] +id: GO:0086090 +name: voltage-gated potassium channel activity involved in SA node cell action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "voltage-gated potassium channel activity involved in SAN cell action potential" EXACT [] +synonym: "voltage-gated potassium channel activity involved in sinoatrial node cell action potential" EXACT [] +synonym: "voltage-gated potassium channel activity involved in sinus node cell action potential" NARROW [] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0086052 ! membrane repolarization during SA node cell action potential +created_by: dph +creation_date: 2011-11-22T01:38:08Z + +[Term] +id: GO:0086091 +name: regulation of heart rate by cardiac conduction +namespace: biological_process +def: "A cardiac conduction process that modulates the frequency or rate of heart contraction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0002027 ! regulation of heart rate +is_a: GO:0061337 ! cardiac conduction +created_by: dph +creation_date: 2011-11-29T01:04:19Z + +[Term] +id: GO:0086092 +name: regulation of the force of heart contraction by cardiac conduction +namespace: biological_process +def: "A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0002026 ! regulation of the force of heart contraction +is_a: GO:0061337 ! cardiac conduction +created_by: dph +creation_date: 2011-11-29T01:26:41Z + +[Term] +id: GO:0086093 +name: G protein-coupled acetylcholine receptor signaling pathway involved in heart process +namespace: biological_process +def: "A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in heart process" EXACT [] +synonym: "G-protein coupled acetylcholine receptor signalling pathway involved in heart process" EXACT [GOC:bf] +synonym: "M2 receptor signaling pathway involved in heart process" NARROW [GOC:mtg_cardiac_conduct_nov11] +synonym: "muscarinic receptor signaling pathway involved in heart process" RELATED [GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway +is_a: GO:0086103 ! G protein-coupled receptor signaling pathway involved in heart process +intersection_of: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: bf + +[Term] +id: GO:0086094 +name: positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction +namespace: biological_process +def: "An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction." [GOC:bf, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21099118] +synonym: "adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction via ryanodine receptor phosphorylation" NARROW [PMID:21099118] +is_a: GO:0140200 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate +relationship: part_of GO:0060452 ! positive regulation of cardiac muscle contraction +created_by: bf + +[Term] +id: GO:0086095 +name: positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +namespace: biological_process +def: "A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, Wikipedia:G_protein-gated_ion_channel] +synonym: "cardiac muscarinic receptor signaling via Gbeta/gamma" RELATED [GOC:mtg_cardiac_conduct_nov11] +synonym: "Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate" RELATED [GOC:mtg_cardiac_conduct_nov11] +synonym: "muscarinic receptor signaling pathway involved in activation of IKACH" EXACT [GOC:mtg_cardiac_conduct_nov11] +synonym: "muscarinic receptor signaling pathway involved in ion channel activation" BROAD [GOC:mtg_cardiac_conduct_nov11] +synonym: "positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling" EXACT [] +is_a: GO:0086033 ! G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +is_a: GO:1900129 ! positive regulation of G-protein activated inward rectifier potassium channel activity +intersection_of: GO:0086033 ! G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +intersection_of: positively_regulates GO:0015467 ! G-protein activated inward rectifier potassium channel activity +created_by: bf + +[Term] +id: GO:0086096 +name: adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10571541] +comment: Although Beta1-adrenergic receptors couple exclusively to the Gs protein, Beta2-adrenergic receptors couple to both Gs and Gi proteins. Coupling to Gi proteins may localize the Gs-mediated signaling. +synonym: "cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity" EXACT [GOC:bf] +synonym: "G-inhibitory-coupled Beta2AR signaling pathway involved in heart process" EXACT [PMID:17376402] +synonym: "Gi-coupled adrenergic receptor signaling pathway involved in heart process" EXACT [PMID:10571541] +synonym: "Gi-coupled Beta2-AR signaling pathway involved in heart process" EXACT [PMID:10571541] +is_a: GO:0071881 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway +is_a: GO:0086103 ! G protein-coupled receptor signaling pathway involved in heart process +intersection_of: GO:0071881 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: bf + +[Term] +id: GO:0086097 +name: phospholipase C-activating angiotensin-activated signaling pathway +namespace: biological_process +def: "An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores." [GOC:bf, GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "angiotensin-mediated signaling pathway via activation of phospholipase C" EXACT [GOC:bf] +synonym: "Gq-coupled angiotensin receptor signaling pathway" EXACT [GOC:bf] +synonym: "phospholipase C-activating angiotensin receptor signaling pathway" EXACT [GOC:bf] +synonym: "phospholipase C-activating angiotensin-mediated signaling pathway" RELATED [] +synonym: "PLC-activating angiotensin receptor signaling pathway" EXACT [GOC:bf] +is_a: GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +is_a: GO:0038166 ! angiotensin-activated signaling pathway +created_by: bf +creation_date: 2012-06-13T11:28:15Z + +[Term] +id: GO:0086098 +name: angiotensin-activated signaling pathway involved in heart process +namespace: biological_process +def: "An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402] +synonym: "angiotensin receptor signaling pathway involved in heart process" EXACT [GOC:bf] +synonym: "angiotensin receptor signalling pathway involved in heart process" EXACT [GOC:bf] +synonym: "angiotensin-mediated signaling pathway involved in heart process" RELATED [] +is_a: GO:0038166 ! angiotensin-activated signaling pathway +is_a: GO:0086103 ! G protein-coupled receptor signaling pathway involved in heart process +intersection_of: GO:0038166 ! angiotensin-activated signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: bf + +[Term] +id: GO:0086099 +name: phospholipase C-activating angiotensin-activated signaling pathway involved in heart process +namespace: biological_process +def: "An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402] +synonym: "angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process" EXACT [GOC:bf] +synonym: "cardiac angiotensin receptor signaling pathway via activation of PLC" EXACT [GOC:bf] +synonym: "Gq-coupled angiotensin receptor signaling pathway involved in heart process" EXACT [PMID:17376402] +synonym: "phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process" RELATED [] +synonym: "PLC-activating angiotensin receptor signaling pathway involved in heart process" EXACT [GOC:bf] +is_a: GO:0086097 ! phospholipase C-activating angiotensin-activated signaling pathway +is_a: GO:0086098 ! angiotensin-activated signaling pathway involved in heart process +intersection_of: GO:0086097 ! phospholipase C-activating angiotensin-activated signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: bf + +[Term] +id: GO:0086100 +name: endothelin receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10977869] +synonym: "endothelin signaling pathway" RELATED [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: bf + +[Term] +id: GO:0086101 +name: endothelin receptor signaling pathway involved in heart process +namespace: biological_process +def: "An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402] +synonym: "endothelin receptor signalling pathway involved in heart process" EXACT [GOC:bf] +is_a: GO:0086100 ! endothelin receptor signaling pathway +is_a: GO:0086103 ! G protein-coupled receptor signaling pathway involved in heart process +intersection_of: GO:0086100 ! endothelin receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +created_by: bf + +[Term] +id: GO:0086102 +name: adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +namespace: biological_process +def: "A G protein-coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "AC-inhibiting muscarinic receptor signaling pathway involved in negative regulation of heart rate" RELATED [GOC:bf] +synonym: "adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate" EXACT [] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate via inhibition of adenylate cyclase activity" EXACT [GOC:bf] +synonym: "Gi-coupled G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate" BROAD [GOC:bf] +synonym: "muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of funny current" EXACT [GOC:mtg_cardiac_conduct_nov11] +synonym: "muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of If channel" EXACT [GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0007197 ! adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway +is_a: GO:0086033 ! G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate +intersection_of: GO:0007197 ! adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway +intersection_of: part_of GO:0010459 ! negative regulation of heart rate +created_by: bf + +[Term] +id: GO:0086103 +name: G protein-coupled receptor signaling pathway involved in heart process +namespace: biological_process +def: "An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402] +synonym: "G-protein coupled receptor signaling pathway involved in heart process" EXACT [GOC:bf] +synonym: "G-protein coupled receptor signalling pathway involved in heart process" EXACT [GOC:bf] +synonym: "GPCR signaling pathway involved in cardiac process" EXACT [GOC:bf] +synonym: "GPCR signaling pathway involved in heart process" EXACT [GOC:bf] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +relationship: part_of GO:0003015 ! heart process +created_by: bf +creation_date: 2012-03-19T01:28:23Z + +[Term] +id: GO:0089700 +name: protein kinase D signaling +namespace: biological_process +def: "A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound." [GOC:BHF, GOC:dos, GOC:mah] +synonym: "PKD signal transduction" EXACT [GOC:signaling] +synonym: "PKD signaling cascade" RELATED [GOC:mah] +synonym: "protein kinase D signal transduction" EXACT [GOC:signaling] +synonym: "protein kinase D signaling cascade" RELATED [GOC:signaling] +synonym: "protein kinase D signalling cascade" RELATED [GOC:mah] +is_a: GO:0035556 ! intracellular signal transduction + +[Term] +id: GO:0089701 +name: U2AF +namespace: cellular_component +def: "A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point." [GOC:dos, GOC:mah, PMID:15231733, PMID:1538748, PMID:2963698, PMID:8657565] +synonym: "U2 accessory factor" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus + +[Term] +id: GO:0089702 +name: undecaprenyl-phosphate glucose phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol." [EC:2.7.8.31, GOC:dos, GOC:imk] +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0089703 +name: L-aspartate transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane." [PMID:21307582] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0034487 ! vacuolar amino acid transmembrane transport +is_a: GO:0070778 ! L-aspartate transmembrane transport + +[Term] +id: GO:0089704 +name: L-glutamate transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane." [PMID:21307582] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0032974 ! amino acid transmembrane export from vacuole +is_a: GO:0046618 ! drug export +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport + +[Term] +id: GO:0089705 +name: protein localization to outer membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane." [GOC:dos, PMID:12823819] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0089706 +name: L-ornithine transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane." [PMID:21307582] +is_a: GO:0032974 ! amino acid transmembrane export from vacuole +is_a: GO:0046618 ! drug export +is_a: GO:1903352 ! L-ornithine transmembrane transport + +[Term] +id: GO:0089707 +name: L-lysine transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-lysine out of the vacuole, across the vacuolar membrane." [PMID:21307582] +is_a: GO:0032974 ! amino acid transmembrane export from vacuole +is_a: GO:0046618 ! drug export +is_a: GO:1903401 ! L-lysine transmembrane transport + +[Term] +id: GO:0089708 +name: L-histidine transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-histidine out of the vacuole, across the vacuolar membrane." [PMID:21307582] +is_a: GO:0032974 ! amino acid transmembrane export from vacuole +is_a: GO:0046618 ! drug export +is_a: GO:0089709 ! L-histidine transmembrane transport +is_a: GO:1902024 ! L-histidine transport +is_a: GO:1990822 ! basic amino acid transmembrane transport + +[Term] +id: GO:0089709 +name: L-histidine transmembrane transport +namespace: biological_process +def: "The directed movement of L-histidine across a membrane." [PMID:21307582] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015801 ! aromatic amino acid transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport + +[Term] +id: GO:0089710 +name: endocytic targeting sequence binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits." [PMID:8918456] +is_a: GO:0005515 ! protein binding + +[Term] +id: GO:0089713 +name: Cbf1-Met4-Met28 complex +namespace: cellular_component +def: "A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation." [PMID:8665859, PMID:9171357] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0089714 +name: UDP-N-acetyl-D-mannosamine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+." [EC:1.1.1.336] +xref: EC:1.1.1.336 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0089715 +name: tRNA m6t6A37 methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine." [PMID:25063302] +comment: This activity is distinct from 'tRNA (adenine-N6-)-methyltransferase activity' (GO:0016430) in that it requires the presence of a threonylcarbamoyl modification. +xref: MetaCyc:RXN0-7114 +is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity + +[Term] +id: GO:0089716 +name: Pip2-Oaf1 complex +namespace: cellular_component +def: "A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins." [PMID:8972187, PMID:9288897] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0089717 +name: spanning component of membrane +namespace: cellular_component +def: "The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane." [GOC:dos] +is_a: GO:0016021 ! integral component of membrane + +[Term] +id: GO:0089718 +name: amino acid import across plasma membrane +namespace: biological_process +alt_id: GO:0043092 +alt_id: GO:0044745 +alt_id: GO:1902837 +def: "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol." [GOC:krc, PMID:8195186] +synonym: "amino acid import into cell" EXACT [] +synonym: "amino acid transmembrane import" BROAD [] +synonym: "L-amino acid import" BROAD [] +synonym: "L-amino acid uptake" NARROW [] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0043090 ! amino acid import +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: jl +creation_date: 2012-11-14T14:21:41Z + +[Term] +id: GO:0089719 +name: RHG protein domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif)." [GOC:dos, GOC:ha] +synonym: "iap binding domain binding" EXACT [] +synonym: "inhibitor of apoptosis binding domain binding" EXACT [] +synonym: "reaper hid grim domain binding" EXACT [] +synonym: "RHG domain binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0089720 +name: caspase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a caspase family protein." [GOC:dos, GOC:ha] +is_a: GO:0002020 ! protease binding + +[Term] +id: GO:0089721 +name: phosphoenolpyruvate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other." [GOC:dos] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +relationship: part_of GO:0089722 ! phosphoenolpyruvate transmembrane transport + +[Term] +id: GO:0089722 +name: phosphoenolpyruvate transmembrane transport +namespace: biological_process +def: "The directed movement of phosphoenolpytuvate across a membrane." [GOC:dos] +is_a: GO:0015714 ! phosphoenolpyruvate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport + +[Term] +id: GO:0090001 +name: replication fork arrest at tRNA locus +namespace: biological_process +def: "A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit." [GOC:dph, GOC:tb] +is_a: GO:0043111 ! replication fork arrest +created_by: tb +creation_date: 2009-06-24T11:36:15Z + +[Term] +id: GO:0090006 +name: regulation of linear element assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase." [GOC:tb] +synonym: "regulation of linear element assembly" RELATED [GOC:dph] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0060629 ! regulation of homologous chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030999 ! linear element assembly +relationship: regulates GO:0030999 ! linear element assembly +created_by: tb +creation_date: 2009-07-17T01:05:13Z + +[Term] +id: GO:0090007 +name: obsolete regulation of mitotic anaphase +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic anaphase, a cell cycle process comprising the steps by which a cell progresses through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other." [GOC:tb] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "regulation of mitotic anaphase" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2009-07-17T01:08:58Z + +[Term] +id: GO:0090008 +name: hypoblast development +namespace: biological_process +def: "The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009888 ! tissue development +created_by: tb +creation_date: 2009-07-29T10:25:54Z + +[Term] +id: GO:0090009 +name: primitive streak formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0001702 ! gastrulation with mouth forming second +relationship: part_of GO:0009948 ! anterior/posterior axis specification +created_by: tb +creation_date: 2009-07-29T10:31:31Z + +[Term] +id: GO:0090010 +name: transforming growth factor beta receptor signaling pathway involved in primitive streak formation +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "TGFbeta signaling pathway involved in primitive streak formation" RELATED [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "transforming growth factor beta receptor signalling pathway involved in primitive streak formation" EXACT [GOC:mah] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0090009 ! primitive streak formation +relationship: part_of GO:0090009 ! primitive streak formation +created_by: tb +creation_date: 2009-07-29T10:38:40Z + +[Term] +id: GO:0090011 +name: Wnt signaling pathway involved in primitive streak formation +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "Wnt receptor signaling pathway involved in primitive streak formation" EXACT [] +synonym: "Wnt receptor signalling pathway involved in primitive streak formation" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in primitive streak formation" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0090009 ! primitive streak formation +relationship: part_of GO:0090009 ! primitive streak formation +created_by: tb +creation_date: 2009-07-29T10:44:53Z + +[Term] +id: GO:0090012 +name: negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "negative regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation" EXACT [GOC:mah] +is_a: GO:0030512 ! negative regulation of transforming growth factor beta receptor signaling pathway +is_a: GO:0090013 ! regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090010 ! transforming growth factor beta receptor signaling pathway involved in primitive streak formation +relationship: negatively_regulates GO:0090010 ! transforming growth factor beta receptor signaling pathway involved in primitive streak formation +created_by: tb +creation_date: 2009-07-29T10:51:57Z + +[Term] +id: GO:0090013 +name: regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation" EXACT [GOC:mah] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090010 ! transforming growth factor beta receptor signaling pathway involved in primitive streak formation +relationship: regulates GO:0090010 ! transforming growth factor beta receptor signaling pathway involved in primitive streak formation +created_by: tb +creation_date: 2009-07-29T10:54:44Z + +[Term] +id: GO:0090014 +name: leaflet formation +namespace: biological_process +def: "The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0060794 ! leaflet morphogenesis +created_by: tb +creation_date: 2009-07-29T11:05:37Z + +[Term] +id: GO:0090015 +name: positive regulation of leaflet formation by auxin mediated signaling pathway +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "positive regulation of leaflet formation by auxin mediated signalling pathway" EXACT [GOC:mah] +is_a: GO:0009734 ! auxin-activated signaling pathway +is_a: GO:0090016 ! regulation of leaflet formation +is_a: GO:1905423 ! positive regulation of plant organ morphogenesis +is_a: GO:1905623 ! positive regulation of leaf development +relationship: positively_regulates GO:0090014 ! leaflet formation +created_by: tb +creation_date: 2009-07-29T11:18:45Z + +[Term] +id: GO:0090016 +name: regulation of leaflet formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leaflet formation." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:1901371 ! regulation of leaf morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090014 ! leaflet formation +relationship: regulates GO:0090014 ! leaflet formation +created_by: tb +creation_date: 2009-07-29T11:23:48Z + +[Term] +id: GO:0090017 +name: anterior neural plate formation +namespace: biological_process +def: "The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021990 ! neural plate formation +created_by: tb +creation_date: 2009-07-29T11:31:35Z + +[Term] +id: GO:0090018 +name: posterior neural plate formation +namespace: biological_process +def: "The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0021990 ! neural plate formation +created_by: tb +creation_date: 2009-07-29T11:32:08Z + +[Term] +id: GO:0090019 +name: obsolete regulation of transcription involved in anterior neural plate formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: tb +creation_date: 2009-07-29T11:38:28Z + +[Term] +id: GO:0090020 +name: obsolete regulation of transcription involved in posterior neural plate formation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate." [GOC:dph, GOC:sdb_2009, GOC:tb] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: tb +creation_date: 2009-07-29T11:39:29Z + +[Term] +id: GO:0090021 +name: positive regulation of posterior neural plate formation by Wnt signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation." [GOC:dph, GOC:sdb_2009, GOC:tb] +synonym: "positive regulation of posterior neural plate formation by Wnt receptor signaling pathway" EXACT [] +synonym: "positive regulation of posterior neural plate formation by Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of posterior neural plate formation by Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +relationship: positively_regulates GO:0090018 ! posterior neural plate formation +created_by: tb +creation_date: 2009-07-29T11:44:13Z + +[Term] +id: GO:0090022 +name: regulation of neutrophil chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding." [GOC:dph, GOC:tb] +is_a: GO:0071622 ! regulation of granulocyte chemotaxis +is_a: GO:1902622 ! regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030593 ! neutrophil chemotaxis +relationship: regulates GO:0030593 ! neutrophil chemotaxis +created_by: tb +creation_date: 2009-08-03T10:09:34Z + +[Term] +id: GO:0090023 +name: positive regulation of neutrophil chemotaxis +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding." [GOC:dph, GOC:tb] +is_a: GO:0071624 ! positive regulation of granulocyte chemotaxis +is_a: GO:0090022 ! regulation of neutrophil chemotaxis +is_a: GO:1902624 ! positive regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030593 ! neutrophil chemotaxis +relationship: positively_regulates GO:0030593 ! neutrophil chemotaxis +created_by: tb +creation_date: 2009-08-03T10:12:23Z + +[Term] +id: GO:0090024 +name: negative regulation of neutrophil chemotaxis +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding." [GOC:dph, GOC:tb] +is_a: GO:0071623 ! negative regulation of granulocyte chemotaxis +is_a: GO:0090022 ! regulation of neutrophil chemotaxis +is_a: GO:1902623 ! negative regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030593 ! neutrophil chemotaxis +relationship: negatively_regulates GO:0030593 ! neutrophil chemotaxis +created_by: tb +creation_date: 2009-08-03T10:13:09Z + +[Term] +id: GO:0090025 +name: regulation of monocyte chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of monocyte chemotaxis." [GOC:dph, GOC:tb] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +is_a: GO:0071675 ! regulation of mononuclear cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002548 ! monocyte chemotaxis +relationship: regulates GO:0002548 ! monocyte chemotaxis +created_by: tb +creation_date: 2009-08-03T10:17:03Z + +[Term] +id: GO:0090026 +name: positive regulation of monocyte chemotaxis +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of monocyte chemotaxis." [GOC:dph, GOC:tb] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:0071677 ! positive regulation of mononuclear cell migration +is_a: GO:0090025 ! regulation of monocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002548 ! monocyte chemotaxis +relationship: positively_regulates GO:0002548 ! monocyte chemotaxis +created_by: tb +creation_date: 2009-08-03T10:18:54Z + +[Term] +id: GO:0090027 +name: negative regulation of monocyte chemotaxis +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of monocyte chemotaxis." [GOC:dph, GOC:tb] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:0071676 ! negative regulation of mononuclear cell migration +is_a: GO:0090025 ! regulation of monocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002548 ! monocyte chemotaxis +relationship: negatively_regulates GO:0002548 ! monocyte chemotaxis +created_by: tb +creation_date: 2009-08-03T10:19:40Z + +[Term] +id: GO:0090028 +name: positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0010969 ! regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +is_a: GO:0060239 ! positive regulation of signal transduction involved in conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +relationship: positively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +created_by: tb +creation_date: 2009-08-03T10:25:27Z + +[Term] +id: GO:0090029 +name: negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] +is_a: GO:0010969 ! regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +is_a: GO:0060240 ! negative regulation of signal transduction involved in conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +relationship: negatively_regulates GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion +created_by: tb +creation_date: 2009-08-03T10:27:04Z + +[Term] +id: GO:0090030 +name: regulation of steroid hormone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones." [GOC:dph, GOC:tb] +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +created_by: tb +creation_date: 2009-08-03T10:38:27Z + +[Term] +id: GO:0090031 +name: positive regulation of steroid hormone biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones." [GOC:dph, GOC:tb] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +created_by: tb +creation_date: 2009-08-03T10:40:32Z + +[Term] +id: GO:0090032 +name: negative regulation of steroid hormone biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones." [GOC:dph, GOC:tb] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0090030 ! regulation of steroid hormone biosynthetic process +created_by: tb +creation_date: 2009-08-03T10:41:35Z + +[Term] +id: GO:0090033 +name: positive regulation of filamentous growth +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape." [GOC:dph, GOC:tb] +is_a: GO:0010570 ! regulation of filamentous growth +is_a: GO:0045927 ! positive regulation of growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030447 ! filamentous growth +relationship: positively_regulates GO:0030447 ! filamentous growth +created_by: tb +creation_date: 2009-08-03T11:04:21Z + +[Term] +id: GO:0090034 +name: regulation of chaperone-mediated protein complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051131 ! chaperone-mediated protein complex assembly +relationship: regulates GO:0051131 ! chaperone-mediated protein complex assembly +created_by: tb +creation_date: 2009-08-03T11:12:37Z + +[Term] +id: GO:0090035 +name: positive regulation of chaperone-mediated protein complex assembly +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0090034 ! regulation of chaperone-mediated protein complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051131 ! chaperone-mediated protein complex assembly +relationship: positively_regulates GO:0051131 ! chaperone-mediated protein complex assembly +created_by: tb +creation_date: 2009-08-03T11:15:25Z + +[Term] +id: GO:0090036 +name: regulation of protein kinase C signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound." [GOC:dph, GOC:tb] +synonym: "regulation of protein kinase C signaling cascade" RELATED [GOC:signaling] +synonym: "regulation of protein kinase C signalling cascade" RELATED [GOC:mah] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070528 ! protein kinase C signaling +relationship: regulates GO:0070528 ! protein kinase C signaling +created_by: tb +creation_date: 2009-08-03T11:27:26Z + +[Term] +id: GO:0090037 +name: positive regulation of protein kinase C signaling +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound." [GOC:dph, GOC:tb] +synonym: "positive regulation of protein kinase C signaling cascade" RELATED [GOC:signaling] +synonym: "positive regulation of protein kinase C signalling cascade" EXACT [GOC:mah] +is_a: GO:0090036 ! regulation of protein kinase C signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070528 ! protein kinase C signaling +relationship: positively_regulates GO:0070528 ! protein kinase C signaling +created_by: tb +creation_date: 2009-08-03T11:28:44Z + +[Term] +id: GO:0090038 +name: negative regulation of protein kinase C signaling +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound." [GOC:dph, GOC:tb] +synonym: "negative regulation of protein kinase C signaling cascade" RELATED [GOC:signaling] +synonym: "negative regulation of protein kinase C signalling cascade" RELATED [GOC:mah] +is_a: GO:0090036 ! regulation of protein kinase C signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070528 ! protein kinase C signaling +relationship: negatively_regulates GO:0070528 ! protein kinase C signaling +created_by: tb +creation_date: 2009-08-03T11:29:33Z + +[Term] +id: GO:0090042 +name: tubulin deacetylation +namespace: biological_process +def: "The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0006476 ! protein deacetylation +created_by: tb +creation_date: 2009-08-03T11:50:47Z + +[Term] +id: GO:0090043 +name: regulation of tubulin deacetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0090311 ! regulation of protein deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090042 ! tubulin deacetylation +relationship: regulates GO:0090042 ! tubulin deacetylation +created_by: tb +creation_date: 2009-08-03T11:53:07Z + +[Term] +id: GO:0090044 +name: positive regulation of tubulin deacetylation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0090043 ! regulation of tubulin deacetylation +is_a: GO:0090312 ! positive regulation of protein deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090042 ! tubulin deacetylation +relationship: positively_regulates GO:0090042 ! tubulin deacetylation +created_by: tb +creation_date: 2009-08-03T11:54:18Z + +[Term] +id: GO:0090045 +name: positive regulation of deacetylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0150065 ! regulation of deacetylase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0019213 ! deacetylase activity +relationship: positively_regulates GO:0019213 ! deacetylase activity +created_by: tb +creation_date: 2009-08-03T12:00:14Z + +[Term] +id: GO:0090046 +name: obsolete regulation of transcription regulator activity +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GOC:BHF, GOC:rl] +comment: At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term. +synonym: "regulation of transcription regulator activity" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2009-08-07T10:19:57Z + +[Term] +id: GO:0090047 +name: obsolete positive regulation of transcription regulator activity +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GOC:BHF, GOC:rl] +comment: At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term. +synonym: "positive regulation of transcription regulator activity" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2009-08-07T10:24:24Z + +[Term] +id: GO:0090048 +name: obsolete negative regulation of transcription regulator activity +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GOC:BHF, GOC:rl] +comment: At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term. +synonym: "negative regulation of transcription regulator activity" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2009-08-07T10:25:04Z + +[Term] +id: GO:0090049 +name: regulation of cell migration involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration +is_a: GO:1903670 ! regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +relationship: regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +created_by: tb +creation_date: 2009-08-07T10:37:16Z + +[Term] +id: GO:0090050 +name: positive regulation of cell migration involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +is_a: GO:0043536 ! positive regulation of blood vessel endothelial cell migration +is_a: GO:0090049 ! regulation of cell migration involved in sprouting angiogenesis +is_a: GO:1903672 ! positive regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +relationship: positively_regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +created_by: tb +creation_date: 2009-08-07T10:41:09Z + +[Term] +id: GO:0090051 +name: negative regulation of cell migration involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] +is_a: GO:0043537 ! negative regulation of blood vessel endothelial cell migration +is_a: GO:0090049 ! regulation of cell migration involved in sprouting angiogenesis +is_a: GO:1903671 ! negative regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +relationship: negatively_regulates GO:0002042 ! cell migration involved in sprouting angiogenesis +created_by: tb +creation_date: 2009-08-07T10:42:00Z + +[Term] +id: GO:0090052 +name: regulation of pericentric heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin." [GOC:dph, GOC:tb] +synonym: "regulation of chromatin silencing at centromere" EXACT [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +is_a: GO:0090230 ! regulation of centromere complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031508 ! pericentric heterochromatin assembly +relationship: regulates GO:0031508 ! pericentric heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: tb +creation_date: 2009-08-07T10:47:41Z + +[Term] +id: GO:0090053 +name: positive regulation of pericentric heterochromatin assembly +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin." [GOC:dph, GOC:tb] +synonym: "positive regulation of chromatin silencing at centromere" EXACT [] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:0090052 ! regulation of pericentric heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031508 ! pericentric heterochromatin assembly +relationship: positively_regulates GO:0031508 ! pericentric heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: tb +creation_date: 2009-08-07T10:49:40Z + +[Term] +id: GO:0090054 +name: regulation of silent mating-type cassette heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin." [GOC:dph, GOC:tb] +synonym: "regulation of chromatin silencing at silent mating-type cassette" EXACT [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +relationship: regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: tb +creation_date: 2009-08-07T10:52:59Z + +[Term] +id: GO:0090055 +name: positive regulation of silent mating-type cassette heterochromatin assembly +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin." [GOC:dph, GOC:tb] +synonym: "positive regulation of chromatin silencing at silent mating-type cassette" EXACT [] +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:0090054 ! regulation of silent mating-type cassette heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +relationship: positively_regulates GO:0030466 ! silent mating-type cassette heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19112 xsd:anyURI +created_by: tb +creation_date: 2009-08-07T10:54:36Z + +[Term] +id: GO:0090056 +name: regulation of chlorophyll metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll." [GOC:dph, GOC:tb] +is_a: GO:0051193 ! regulation of cofactor metabolic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015994 ! chlorophyll metabolic process +relationship: regulates GO:0015994 ! chlorophyll metabolic process +created_by: tb +creation_date: 2009-08-07T11:47:27Z + +[Term] +id: GO:0090057 +name: root radial pattern formation +namespace: biological_process +def: "The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0009956 ! radial pattern formation +relationship: part_of GO:0048364 ! root development +created_by: tb +creation_date: 2009-08-11T02:58:06Z + +[Term] +id: GO:0090058 +name: metaxylem development +namespace: biological_process +def: "The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0010089 ! xylem development +created_by: tb +creation_date: 2009-08-11T03:05:15Z + +[Term] +id: GO:0090059 +name: protoxylem development +namespace: biological_process +def: "The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:0010089 ! xylem development +created_by: tb +creation_date: 2009-08-11T03:08:06Z + +[Term] +id: GO:0090060 +name: regulation of metaxylem development +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed." [GOC:dph, GOC:sdb_2009, GOC:tb] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090058 ! metaxylem development +relationship: regulates GO:0090058 ! metaxylem development +created_by: tb +creation_date: 2009-08-11T03:14:54Z + +[Term] +id: GO:0090062 +name: regulation of trehalose metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi." [GOC:dph, GOC:tb] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005991 ! trehalose metabolic process +relationship: regulates GO:0005991 ! trehalose metabolic process +created_by: tb +creation_date: 2009-08-12T11:24:29Z + +[Term] +id: GO:0090063 +name: positive regulation of microtubule nucleation +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] +is_a: GO:0010968 ! regulation of microtubule nucleation +is_a: GO:0031116 ! positive regulation of microtubule polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007020 ! microtubule nucleation +relationship: positively_regulates GO:0007020 ! microtubule nucleation +created_by: tb +creation_date: 2009-08-12T11:33:09Z + +[Term] +id: GO:0090064 +name: activation of microtubule nucleation +namespace: biological_process +def: "Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] +is_a: GO:0090063 ! positive regulation of microtubule nucleation +created_by: tb +creation_date: 2009-08-12T11:36:15Z + +[Term] +id: GO:0090065 +name: regulation of production of siRNA involved in RNA interference +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference." [GOC:dph, GOC:mah, GOC:tb] +synonym: "regulation of RNA interference, production of siRNA" EXACT [GOC:mah] +is_a: GO:0070920 ! regulation of production of small RNA involved in gene silencing by RNA +is_a: GO:1900368 ! regulation of RNA interference +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030422 ! production of siRNA involved in RNA interference +relationship: regulates GO:0030422 ! production of siRNA involved in RNA interference +created_by: tb +creation_date: 2009-08-12T11:41:09Z + +[Term] +id: GO:0090066 +name: regulation of anatomical structure size +namespace: biological_process +def: "Any process that modulates the size of an anatomical structure." [GOC:dph, GOC:tb] +is_a: GO:0065008 ! regulation of biological quality +created_by: tb +creation_date: 2009-09-02T11:00:08Z + +[Term] +id: GO:0090067 +name: regulation of thalamus size +namespace: biological_process +def: "Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus." [GOC:dph, GOC:tb] +is_a: GO:0090066 ! regulation of anatomical structure size +created_by: tb +creation_date: 2009-09-02T11:03:03Z + +[Term] +id: GO:0090068 +name: positive regulation of cell cycle process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0045787 ! positive regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022402 ! cell cycle process +relationship: positively_regulates GO:0022402 ! cell cycle process +created_by: tb +creation_date: 2009-09-09T11:39:52Z + +[Term] +id: GO:0090069 +name: regulation of ribosome biogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042254 ! ribosome biogenesis +relationship: regulates GO:0042254 ! ribosome biogenesis +created_by: tb +creation_date: 2009-09-11T10:32:17Z + +[Term] +id: GO:0090070 +name: positive regulation of ribosome biogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0090069 ! regulation of ribosome biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042254 ! ribosome biogenesis +relationship: positively_regulates GO:0042254 ! ribosome biogenesis +created_by: tb +creation_date: 2009-09-11T10:32:17Z + +[Term] +id: GO:0090071 +name: negative regulation of ribosome biogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0090069 ! regulation of ribosome biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042254 ! ribosome biogenesis +relationship: negatively_regulates GO:0042254 ! ribosome biogenesis +created_by: tb +creation_date: 2009-09-11T10:32:17Z + +[Term] +id: GO:0090072 +name: obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels." [GOC:dph, GOC:tb] +comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round. +synonym: "positive regulation of sodium ion transport via voltage-gated sodium channel activity" EXACT [] +is_obsolete: true +consider: GO:0005248 +created_by: tb +creation_date: 2009-09-11T10:46:13Z + +[Term] +id: GO:0090073 +name: positive regulation of protein homodimerization activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer." [GOC:dph, GOC:tb] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:0043496 ! regulation of protein homodimerization activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042803 ! protein homodimerization activity +relationship: positively_regulates GO:0042803 ! protein homodimerization activity +created_by: tb +creation_date: 2009-09-11T11:15:40Z + +[Term] +id: GO:0090074 +name: negative regulation of protein homodimerization activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer." [GOC:dph, GOC:tb] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:0043496 ! regulation of protein homodimerization activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042803 ! protein homodimerization activity +relationship: negatively_regulates GO:0042803 ! protein homodimerization activity +created_by: tb +creation_date: 2009-09-11T11:15:40Z + +[Term] +id: GO:0090075 +name: relaxation of muscle +namespace: biological_process +def: "A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain." [GOC:BHF, GOC:rl, PMID:19996365] +is_a: GO:0003012 ! muscle system process +created_by: tb +creation_date: 2009-09-11T11:43:38Z + +[Term] +id: GO:0090076 +name: relaxation of skeletal muscle +namespace: biological_process +def: "A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases." [GOC:BHF, GOC:rl] +is_a: GO:0090075 ! relaxation of muscle +created_by: tb +creation_date: 2009-09-11T11:44:32Z + +[Term] +id: GO:0090077 +name: foam cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0030154 ! cell differentiation +created_by: tb +creation_date: 2009-09-15T03:46:30Z + +[Term] +id: GO:0090078 +name: smooth muscle derived foam cell differentiation +namespace: biological_process +def: "The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions." [GOC:add, GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0090077 ! foam cell differentiation +property_value: RO:0002161 NCBITaxon:4751 +created_by: tb +creation_date: 2009-09-15T03:48:10Z + +[Term] +id: GO:0090079 +name: translation regulator activity, nucleic acid binding +namespace: molecular_function +def: "Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome." [GOC:dph, GOC:tb, GOC:vw] +is_a: GO:0003676 ! nucleic acid binding +is_a: GO:0045182 ! translation regulator activity +created_by: tb +creation_date: 2009-10-19T10:19:05Z + +[Term] +id: GO:0090080 +name: positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade." [GOC:dph, GOC:tb] +synonym: "positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +is_a: GO:0043410 ! positive regulation of MAPK cascade +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: positively_regulates GO:0000165 ! MAPK cascade +created_by: tb +creation_date: 2009-10-19T11:30:22Z + +[Term] +id: GO:0090081 +name: regulation of heart induction by regulation of canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:mtg_heart] +synonym: "regulation of heart induction by regulation of canonical Wnt receptor signaling pathway" EXACT [] +synonym: "regulation of heart induction by regulation of canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of heart induction by regulation of canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0003307 ! regulation of Wnt signaling pathway involved in heart development +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +is_a: GO:0090381 ! regulation of heart induction +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0100012 ! regulation of heart induction by canonical Wnt signaling pathway +relationship: regulates GO:0100012 ! regulation of heart induction by canonical Wnt signaling pathway +created_by: tb +creation_date: 2009-10-23T10:55:18Z + +[Term] +id: GO:0090082 +name: positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:mtg_heart, PMID:16860783] +synonym: "positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway" EXACT [] +synonym: "positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0003308 ! negative regulation of Wnt signaling pathway involved in heart development +is_a: GO:0090081 ! regulation of heart induction by regulation of canonical Wnt signaling pathway +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:1901321 ! positive regulation of heart induction +created_by: tb +creation_date: 2009-10-23T10:58:03Z + +[Term] +id: GO:0090083 +name: regulation of inclusion body assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070841 ! inclusion body assembly +relationship: regulates GO:0070841 ! inclusion body assembly +created_by: tb +creation_date: 2009-10-23T11:07:22Z + +[Term] +id: GO:0090084 +name: negative regulation of inclusion body assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0090083 ! regulation of inclusion body assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070841 ! inclusion body assembly +relationship: negatively_regulates GO:0070841 ! inclusion body assembly +created_by: tb +creation_date: 2009-10-23T11:08:56Z + +[Term] +id: GO:0090085 +name: regulation of protein deubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016579 ! protein deubiquitination +relationship: regulates GO:0016579 ! protein deubiquitination +created_by: tb +creation_date: 2009-10-23T11:16:32Z + +[Term] +id: GO:0090086 +name: negative regulation of protein deubiquitination +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:0090085 ! regulation of protein deubiquitination +is_a: GO:1903321 ! negative regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016579 ! protein deubiquitination +relationship: negatively_regulates GO:0016579 ! protein deubiquitination +created_by: tb +creation_date: 2009-10-23T11:18:06Z + +[Term] +id: GO:0090087 +name: regulation of peptide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015833 ! peptide transport +relationship: regulates GO:0015833 ! peptide transport +created_by: tb +creation_date: 2009-10-23T11:21:38Z + +[Term] +id: GO:0090088 +name: regulation of oligopeptide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:dph, GOC:tb] +is_a: GO:0090087 ! regulation of peptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006857 ! oligopeptide transport +relationship: regulates GO:0006857 ! oligopeptide transport +created_by: tb +creation_date: 2009-10-23T11:23:18Z + +[Term] +id: GO:0090089 +name: regulation of dipeptide transport +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] +is_a: GO:0090088 ! regulation of oligopeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042938 ! dipeptide transport +relationship: regulates GO:0042938 ! dipeptide transport +created_by: tb +creation_date: 2009-10-23T11:24:36Z + +[Term] +id: GO:0090090 +name: negative regulation of canonical Wnt signaling pathway +namespace: biological_process +alt_id: GO:0035414 +def: "Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:dph, GOC:tb] +synonym: "negative regulation of canonical Wnt receptor signaling pathway" EXACT [] +synonym: "negative regulation of canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "negative regulation of catenin import into nucleus" NARROW [] +synonym: "negative regulation of catenin protein nuclear translocation" NARROW [GOC:mah] +synonym: "negative regulation of Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:mtg_signal] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060070 ! canonical Wnt signaling pathway +relationship: negatively_regulates GO:0060070 ! canonical Wnt signaling pathway +created_by: tb +creation_date: 2009-10-30T11:27:17Z + +[Term] +id: GO:0090091 +name: positive regulation of extracellular matrix disassembly +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb] +is_a: GO:0010715 ! regulation of extracellular matrix disassembly +is_a: GO:1903055 ! positive regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022617 ! extracellular matrix disassembly +relationship: positively_regulates GO:0022617 ! extracellular matrix disassembly +created_by: tb +creation_date: 2009-11-04T10:03:25Z + +[Term] +id: GO:0090092 +name: regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand." [GOC:dph, GOC:tb] +synonym: "regulation of transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +relationship: regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +created_by: tb +creation_date: 2009-11-04T11:46:40Z + +[Term] +id: GO:0090093 +name: regulation of fungal-type cell wall beta-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells." [GOC:dph, GOC:tb] +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0032951 ! regulation of beta-glucan biosynthetic process +is_a: GO:0032995 ! regulation of fungal-type cell wall biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070880 ! fungal-type cell wall beta-glucan biosynthetic process +relationship: regulates GO:0070880 ! fungal-type cell wall beta-glucan biosynthetic process +created_by: tb +creation_date: 2009-11-13T10:10:38Z + +[Term] +id: GO:0090094 +name: metanephric cap mesenchymal cell proliferation involved in metanephros development +namespace: biological_process +def: "The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip." [GOC:dph, GOC:tb, GOC:yaf, PMID:19161241] +is_a: GO:0010463 ! mesenchymal cell proliferation +is_a: GO:0072203 ! cell proliferation involved in metanephros development +relationship: part_of GO:0072186 ! metanephric cap morphogenesis +created_by: tb +creation_date: 2009-11-13T10:34:10Z + +[Term] +id: GO:0090095 +name: regulation of metanephric cap mesenchymal cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090094 ! metanephric cap mesenchymal cell proliferation involved in metanephros development +relationship: regulates GO:0090094 ! metanephric cap mesenchymal cell proliferation involved in metanephros development +created_by: tb +creation_date: 2009-11-13T10:40:32Z + +[Term] +id: GO:0090096 +name: positive regulation of metanephric cap mesenchymal cell proliferation +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:0090095 ! regulation of metanephric cap mesenchymal cell proliferation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090094 ! metanephric cap mesenchymal cell proliferation involved in metanephros development +relationship: positively_regulates GO:0090094 ! metanephric cap mesenchymal cell proliferation involved in metanephros development +created_by: tb +creation_date: 2009-11-13T10:40:32Z + +[Term] +id: GO:0090100 +name: positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand." [GOC:dph, GOC:tb] +synonym: "positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +relationship: positively_regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +created_by: tb +creation_date: 2009-11-13T10:55:53Z + +[Term] +id: GO:0090101 +name: negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand." [GOC:dph, GOC:tb] +synonym: "negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0090092 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +relationship: negatively_regulates GO:0007178 ! transmembrane receptor protein serine/threonine kinase signaling pathway +created_by: tb +creation_date: 2009-11-13T10:56:52Z + +[Term] +id: GO:0090102 +name: cochlea development +namespace: biological_process +def: "The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound." [GOC:dph, GOC:tb] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048839 ! inner ear development +created_by: tb +creation_date: 2009-11-18T11:42:15Z + +[Term] +id: GO:0090103 +name: cochlea morphogenesis +namespace: biological_process +def: "The process in which the cochlea is generated and organized." [GOC:dph, GOC:tb] +is_a: GO:0048598 ! embryonic morphogenesis +relationship: part_of GO:0042472 ! inner ear morphogenesis +relationship: part_of GO:0090102 ! cochlea development +created_by: tb +creation_date: 2009-11-18T11:45:11Z + +[Term] +id: GO:0090104 +name: pancreatic epsilon cell differentiation +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin." [GOC:dph, GOC:tb] +synonym: "pancreatic E cell differentiation" EXACT [] +is_a: GO:0030154 ! cell differentiation +relationship: part_of GO:0031018 ! endocrine pancreas development +created_by: tb +creation_date: 2009-11-18T11:48:52Z + +[Term] +id: GO:0090105 +name: pancreatic E cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure." [GOC:dph, GOC:tb] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0090104 ! pancreatic epsilon cell differentiation +created_by: tb +creation_date: 2009-11-18T11:51:00Z + +[Term] +id: GO:0090106 +name: pancreatic E cell fate commitment +namespace: biological_process +def: "The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell." [GOC:dph, GOC:tb] +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0090104 ! pancreatic epsilon cell differentiation +created_by: tb +creation_date: 2009-11-18T11:51:41Z + +[Term] +id: GO:0090107 +name: regulation of high-density lipoprotein particle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle." [GOC:dph, GOC:tb] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034380 ! high-density lipoprotein particle assembly +relationship: regulates GO:0034380 ! high-density lipoprotein particle assembly +created_by: tb +creation_date: 2009-11-25T10:50:18Z + +[Term] +id: GO:0090108 +name: positive regulation of high-density lipoprotein particle assembly +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0090107 ! regulation of high-density lipoprotein particle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034380 ! high-density lipoprotein particle assembly +relationship: positively_regulates GO:0034380 ! high-density lipoprotein particle assembly +created_by: tb +creation_date: 2009-11-25T10:50:18Z + +[Term] +id: GO:0090109 +name: regulation of cell-substrate junction assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate." [GOC:dph, GOC:tb] +is_a: GO:0150116 ! regulation of cell-substrate junction organization +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0007044 ! cell-substrate junction assembly +relationship: regulates GO:0007044 ! cell-substrate junction assembly +created_by: tb +creation_date: 2009-11-25T11:00:58Z + +[Term] +id: GO:0090110 +name: COPII-coated vesicle cargo loading +namespace: biological_process +def: "The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi." [GOC:ascb_2009, GOC:dph, GOC:lb, GOC:tb] +synonym: "cargo loading into COPII vesicle" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "cargo loading into COPII-coated vesicle" EXACT [] +synonym: "cargo selection into COPII-coated vesicle" EXACT [GOC:vw] +synonym: "COPII coat-cargo complex assembly" RELATED [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0035459 ! vesicle cargo loading +is_a: GO:0046907 ! intracellular transport +is_a: GO:0051668 ! localization within membrane +relationship: part_of GO:0090114 ! COPII-coated vesicle budding +created_by: tb +creation_date: 2009-12-06T08:28:34Z + +[Term] +id: GO:0090111 +name: regulation of COPII vesicle uncoating +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090112 ! COPII vesicle uncoating +relationship: regulates GO:0090112 ! COPII vesicle uncoating +created_by: tb +creation_date: 2009-12-06T08:34:01Z + +[Term] +id: GO:0090112 +name: COPII vesicle uncoating +namespace: biological_process +def: "The process in which COPII vesicle coat proteins are disassembled, and released." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0072319 ! vesicle uncoating +relationship: part_of GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: tb +creation_date: 2009-12-06T08:56:50Z + +[Term] +id: GO:0090113 +name: regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis +namespace: biological_process +def: "The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport +created_by: tb +creation_date: 2009-12-06T09:16:14Z + +[Term] +id: GO:0090114 +name: COPII-coated vesicle budding +namespace: biological_process +def: "The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "COPII vesicle budding" RELATED [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +synonym: "ER exit" NARROW [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +synonym: "ER vesicle budding" BROAD [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0048194 ! Golgi vesicle budding +relationship: part_of GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: tb +creation_date: 2009-12-06T09:21:16Z + +[Term] +id: GO:0090115 +name: obsolete C-5 methylation on cytosine involved in chromatin silencing +namespace: biological_process +def: "OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: This term was obsoleted because it represents a molecular function. +is_obsolete: true +created_by: tb +creation_date: 2009-12-07T11:55:16Z + +[Term] +id: GO:0090116 +name: C-5 methylation of cytosine +namespace: biological_process +def: "The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0032776 ! DNA methylation on cytosine +created_by: tb +creation_date: 2009-12-07T11:58:47Z + +[Term] +id: GO:0090117 +name: endosome to lysosome transport of low-density lipoprotein particle +namespace: biological_process +def: "The directed movement of low-density lipoprotein particle from endosomes to lysosomes." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "endosome to lysosome transport of LDL" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0008333 ! endosome to lysosome transport +is_a: GO:0090119 ! vesicle-mediated cholesterol transport +created_by: tb +creation_date: 2009-12-07T12:04:34Z + +[Term] +id: GO:0090118 +name: receptor-mediated endocytosis involved in cholesterol transport +namespace: biological_process +def: "A receptor-mediated endocytosis process involved in intracellular cholesterol transport." [GOC:ascb_2009, GOC:dph, GOC:pr, GOC:tb] +synonym: "receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [] +synonym: "receptor-mediated endocytosis of LDL" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:dph] +synonym: "receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [] +is_a: GO:0006898 ! receptor-mediated endocytosis +is_a: GO:0046907 ! intracellular transport +intersection_of: GO:0006898 ! receptor-mediated endocytosis +intersection_of: part_of GO:0032367 ! intracellular cholesterol transport +relationship: part_of GO:0032367 ! intracellular cholesterol transport +created_by: tb +creation_date: 2009-12-07T12:06:05Z + +[Term] +id: GO:0090119 +name: vesicle-mediated cholesterol transport +namespace: biological_process +def: "The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0016482 ! cytosolic transport +is_a: GO:0032367 ! intracellular cholesterol transport +created_by: tb +creation_date: 2009-12-07T12:14:37Z + +[Term] +id: GO:0090120 +name: lysosome to ER cholesterol transport +namespace: biological_process +def: "The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum." [GOC:mah] +synonym: "lysosome to endoplasmic reticulum cholesterol transport" EXACT [GOC:mah] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0090119 ! vesicle-mediated cholesterol transport +relationship: occurs_in GO:0005737 ! cytoplasm +created_by: tb +creation_date: 2009-12-07T12:22:12Z + +[Term] +id: GO:0090121 +name: low-density lipoprotein particle disassembly involved in cholesterol transport +namespace: biological_process +def: "The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090495 ! low-density lipoprotein particle disassembly +intersection_of: GO:0090495 ! low-density lipoprotein particle disassembly +intersection_of: part_of GO:0030301 ! cholesterol transport +relationship: part_of GO:0030301 ! cholesterol transport +created_by: tb +creation_date: 2009-12-07T12:59:14Z + +[Term] +id: GO:0090122 +name: cholesterol ester hydrolysis involved in cholesterol transport +namespace: biological_process +def: "The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0008203 ! cholesterol metabolic process +relationship: part_of GO:0090119 ! vesicle-mediated cholesterol transport +created_by: tb +creation_date: 2009-12-07T01:06:54Z + +[Term] +id: GO:0090123 +name: lysosomal glycocalyx +namespace: cellular_component +def: "The polysaccharide-based coating on the inner side of a lysosomal membrane that protects it from digestion by lysosomal enzymes." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005764 ! lysosome +created_by: tb +creation_date: 2009-12-07T01:16:20Z + +[Term] +id: GO:0090124 +name: N-4 methylation of cytosine +namespace: biological_process +def: "The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0032776 ! DNA methylation on cytosine +created_by: tb +creation_date: 2009-12-07T02:40:38Z + +[Term] +id: GO:0090125 +name: cell-cell adhesion involved in synapse maturation +namespace: biological_process +def: "The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "trans-synaptic adhesion" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0098609 ! cell-cell adhesion +intersection_of: GO:0098609 ! cell-cell adhesion +intersection_of: part_of GO:0060074 ! synapse maturation +relationship: part_of GO:0060074 ! synapse maturation +created_by: tb +creation_date: 2009-12-07T02:43:24Z + +[Term] +id: GO:0090126 +name: protein-containing complex assembly involved in synapse maturation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "protein complex assembly involved in synapse maturation" RELATED [] +is_a: GO:0065003 ! protein-containing complex assembly +intersection_of: GO:0065003 ! protein-containing complex assembly +intersection_of: part_of GO:0060074 ! synapse maturation +relationship: part_of GO:0060074 ! synapse maturation +created_by: tb +creation_date: 2009-12-07T02:49:28Z + +[Term] +id: GO:0090127 +name: positive regulation of synapse maturation by synaptic transmission +namespace: biological_process +def: "Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007268 ! chemical synaptic transmission +is_a: GO:0090129 ! positive regulation of synapse maturation +intersection_of: GO:0007268 ! chemical synaptic transmission +intersection_of: positively_regulates GO:0060074 ! synapse maturation +created_by: tb +creation_date: 2009-12-07T02:57:21Z + +[Term] +id: GO:0090128 +name: regulation of synapse maturation +namespace: biological_process +def: "Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state." [GOC:ascb_2009, GOC:dph, GOC:tb] +subset: goslim_synapse +is_a: GO:0050807 ! regulation of synapse organization +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060074 ! synapse maturation +relationship: regulates GO:0060074 ! synapse maturation +created_by: tb +creation_date: 2009-12-07T03:00:58Z + +[Term] +id: GO:0090129 +name: positive regulation of synapse maturation +namespace: biological_process +def: "Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:0090128 ! regulation of synapse maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060074 ! synapse maturation +relationship: positively_regulates GO:0060074 ! synapse maturation +created_by: tb +creation_date: 2009-12-07T03:00:58Z + +[Term] +id: GO:0090130 +name: tissue migration +namespace: biological_process +def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0032501 ! multicellular organismal process +created_by: tb +creation_date: 2009-12-07T03:13:55Z + +[Term] +id: GO:0090131 +name: mesenchyme migration +namespace: biological_process +def: "The process in which the population of cells that make up a mesenchyme undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090130 ! tissue migration +relationship: part_of GO:0072132 ! mesenchyme morphogenesis +created_by: tb +creation_date: 2009-12-07T03:15:17Z + +[Term] +id: GO:0090132 +name: epithelium migration +namespace: biological_process +def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090130 ! tissue migration +created_by: tb +creation_date: 2009-12-07T03:19:34Z + +[Term] +id: GO:0090133 +name: mesendoderm migration +namespace: biological_process +def: "The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090132 ! epithelium migration +relationship: part_of GO:0007369 ! gastrulation +relationship: part_of GO:0048382 ! mesendoderm development +created_by: tb +creation_date: 2009-12-07T03:22:08Z + +[Term] +id: GO:0090134 +name: cell migration involved in mesendoderm migration +namespace: biological_process +def: "The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0042074 ! cell migration involved in gastrulation +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0090133 ! mesendoderm migration +relationship: part_of GO:0090133 ! mesendoderm migration +created_by: tb +creation_date: 2009-12-07T03:28:11Z + +[Term] +id: GO:0090135 +name: actin filament branching +namespace: biological_process +def: "The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007015 ! actin filament organization +created_by: tb +creation_date: 2009-12-08T01:53:14Z + +[Term] +id: GO:0090136 +name: epithelial cell-cell adhesion +namespace: biological_process +def: "The attachment of an epithelial cell to another epithelial cell via adhesion molecules." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0098609 ! cell-cell adhesion +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: tb +creation_date: 2009-12-08T01:56:53Z + +[Term] +id: GO:0090137 +name: epithelial cell-cell adhesion involved in epithelium migration +namespace: biological_process +def: "The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090136 ! epithelial cell-cell adhesion +intersection_of: GO:0090136 ! epithelial cell-cell adhesion +intersection_of: part_of GO:0090132 ! epithelium migration +relationship: part_of GO:0090132 ! epithelium migration +created_by: tb +creation_date: 2009-12-08T01:58:19Z + +[Term] +id: GO:0090138 +name: regulation of actin cytoskeleton organization by cell-cell adhesion +namespace: biological_process +def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +is_a: GO:0098609 ! cell-cell adhesion +intersection_of: GO:0098609 ! cell-cell adhesion +intersection_of: regulates GO:0030036 ! actin cytoskeleton organization +created_by: tb +creation_date: 2009-12-08T02:05:00Z + +[Term] +id: GO:0090139 +name: mitochondrial DNA packaging +namespace: biological_process +def: "Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0036385 ! nucleoid DNA packaging +intersection_of: GO:0006323 ! DNA packaging +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +created_by: tb +creation_date: 2009-12-08T02:12:19Z + +[Term] +id: GO:0090140 +name: regulation of mitochondrial fission +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of mitochondrial division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000266 ! mitochondrial fission +relationship: regulates GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T02:20:48Z + +[Term] +id: GO:0090141 +name: positive regulation of mitochondrial fission +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "positive regulation of mitochondrial division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0090140 ! regulation of mitochondrial fission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000266 ! mitochondrial fission +relationship: positively_regulates GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T02:20:48Z + +[Term] +id: GO:0090143 +name: nucleoid organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "nucleoid organisation" EXACT [GOC:mah] +is_a: GO:0016043 ! cellular component organization +created_by: tb +creation_date: 2009-12-08T02:35:48Z + +[Term] +id: GO:0090144 +name: mitochondrial nucleoid organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "mitochondrial nucleoid organisation" EXACT [GOC:mah] +is_a: GO:0090143 ! nucleoid organization +intersection_of: GO:0090143 ! nucleoid organization +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +created_by: tb +creation_date: 2009-12-08T02:38:26Z + +[Term] +id: GO:0090145 +name: mitochondrial nucleoid organization involved in mitochondrial fission +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "mitochondrial nucleoid organisation involved in mitochondrial fission" EXACT [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb] +is_a: GO:0090144 ! mitochondrial nucleoid organization +intersection_of: GO:0090144 ! mitochondrial nucleoid organization +intersection_of: part_of GO:0000266 ! mitochondrial fission +relationship: part_of GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T02:39:34Z + +[Term] +id: GO:0090146 +name: establishment of mitochondrion localization involved in mitochondrial fission +namespace: biological_process +def: "The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "establishment of mitochondrion localisation involved in mitochondrial fission" EXACT [GOC:mah] +synonym: "mitochondrial localization involved in mitochondrial fission" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051654 ! establishment of mitochondrion localization +intersection_of: GO:0051654 ! establishment of mitochondrion localization +intersection_of: part_of GO:0000266 ! mitochondrial fission +relationship: part_of GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T02:53:15Z + +[Term] +id: GO:0090147 +name: regulation of establishment of mitochondrion localization involved in mitochondrial fission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of establishment of mitochondrion localisation involved in mitochondrial fission" EXACT [GOC:mah] +synonym: "regulation of mitochondrial localization involved in mitochondrial fission" RELATED [GOC:dph, GOC:tb] +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0090140 ! regulation of mitochondrial fission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090146 ! establishment of mitochondrion localization involved in mitochondrial fission +relationship: regulates GO:0090146 ! establishment of mitochondrion localization involved in mitochondrial fission +created_by: tb +creation_date: 2009-12-08T03:01:01Z + +[Term] +id: GO:0090148 +name: membrane fission +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "membrane scission" EXACT [] +is_a: GO:0061024 ! membrane organization +created_by: tb +creation_date: 2009-12-08T03:06:36Z + +[Term] +id: GO:0090149 +name: mitochondrial membrane fission +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "membrane fission involved in mitochondrial fission" EXACT [] +synonym: "mitochondrial membrane scission" EXACT [] +is_a: GO:0090148 ! membrane fission +intersection_of: GO:0090148 ! membrane fission +intersection_of: part_of GO:0000266 ! mitochondrial fission +relationship: part_of GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T03:08:57Z + +[Term] +id: GO:0090150 +name: establishment of protein localization to membrane +namespace: biological_process +def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah] +synonym: "establishment of protein localization in membrane" EXACT [] +is_a: GO:0045184 ! establishment of protein localization +is_a: GO:0072657 ! protein localization to membrane +created_by: tb +creation_date: 2009-12-08T03:18:51Z + +[Term] +id: GO:0090151 +name: establishment of protein localization to mitochondrial membrane +namespace: biological_process +def: "The directed movement of a protein to a specific location in the mitochondrial membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "establishment of protein localisation in mitochondrial membrane" EXACT [GOC:mah] +synonym: "establishment of protein localization in mitochondrial membrane" EXACT [] +is_a: GO:0007006 ! mitochondrial membrane organization +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0072655 ! establishment of protein localization to mitochondrion +is_a: GO:0090150 ! establishment of protein localization to membrane +created_by: tb +creation_date: 2009-12-08T03:18:51Z + +[Term] +id: GO:0090152 +name: establishment of protein localization to mitochondrial membrane involved in mitochondrial fission +namespace: biological_process +def: "The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission" EXACT [GOC:mah] +synonym: "establishment of protein localization in mitochondrial membrane involved in mitochondrial fission" EXACT [] +is_a: GO:0090151 ! establishment of protein localization to mitochondrial membrane +intersection_of: GO:0090151 ! establishment of protein localization to mitochondrial membrane +intersection_of: part_of GO:0000266 ! mitochondrial fission +relationship: part_of GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2009-12-08T03:18:51Z + +[Term] +id: GO:0090153 +name: regulation of sphingolipid biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1905038 ! regulation of membrane lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030148 ! sphingolipid biosynthetic process +relationship: regulates GO:0030148 ! sphingolipid biosynthetic process +created_by: tb +creation_date: 2009-12-08T03:25:49Z + +[Term] +id: GO:0090154 +name: positive regulation of sphingolipid biosynthetic process +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030148 ! sphingolipid biosynthetic process +relationship: positively_regulates GO:0030148 ! sphingolipid biosynthetic process +created_by: tb +creation_date: 2009-12-08T03:27:33Z + +[Term] +id: GO:0090155 +name: negative regulation of sphingolipid biosynthetic process +namespace: biological_process +alt_id: GO:0090157 +def: "Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis" RELATED [] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030148 ! sphingolipid biosynthetic process +relationship: negatively_regulates GO:0030148 ! sphingolipid biosynthetic process +created_by: tb +creation_date: 2009-12-08T03:33:39Z + +[Term] +id: GO:0090156 +name: cellular sphingolipid homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:0055088 ! lipid homeostasis +created_by: tb +creation_date: 2009-12-08T08:21:36Z + +[Term] +id: GO:0090158 +name: endoplasmic reticulum membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "endoplasmic reticulum membrane organisation" EXACT [GOC:mah] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0007029 ! endoplasmic reticulum organization +created_by: tb +creation_date: 2009-12-08T08:27:17Z + +[Term] +id: GO:0090159 +name: sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation" EXACT [GOC:mah] +is_a: GO:0030148 ! sphingolipid biosynthetic process +intersection_of: GO:0030148 ! sphingolipid biosynthetic process +intersection_of: part_of GO:0090158 ! endoplasmic reticulum membrane organization +relationship: part_of GO:0090158 ! endoplasmic reticulum membrane organization +created_by: tb +creation_date: 2009-12-08T08:31:13Z + +[Term] +id: GO:0090160 +name: Golgi to lysosome transport +namespace: biological_process +def: "The directed movement of substances from the Golgi to lysosomes." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0006896 ! Golgi to vacuole transport +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0016482 ! cytosolic transport +created_by: tb +creation_date: 2009-12-08T08:35:13Z + +[Term] +id: GO:0090161 +name: Golgi ribbon formation +namespace: biological_process +def: "The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007030 ! Golgi organization +created_by: tb +creation_date: 2009-12-08T08:38:14Z + +[Term] +id: GO:0090162 +name: establishment of epithelial cell polarity +namespace: biological_process +def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0030010 ! establishment of cell polarity +created_by: tb +creation_date: 2009-12-08T08:58:27Z + +[Term] +id: GO:0090163 +name: establishment of epithelial cell planar polarity +namespace: biological_process +def: "The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090162 ! establishment of epithelial cell polarity +created_by: tb +creation_date: 2009-12-08T08:59:57Z + +[Term] +id: GO:0090164 +name: asymmetric Golgi ribbon formation +namespace: biological_process +def: "The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090161 ! Golgi ribbon formation +relationship: part_of GO:0090162 ! establishment of epithelial cell polarity +created_by: tb +creation_date: 2009-12-08T09:02:45Z + +[Term] +id: GO:0090165 +name: regulation of secretion by asymmetric Golgi ribbon formation +namespace: biological_process +def: "The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0051046 ! regulation of secretion +is_a: GO:0090164 ! asymmetric Golgi ribbon formation +intersection_of: GO:0090164 ! asymmetric Golgi ribbon formation +intersection_of: regulates GO:0046903 ! secretion +created_by: tb +creation_date: 2009-12-08T09:05:16Z + +[Term] +id: GO:0090166 +name: Golgi disassembly +namespace: biological_process +def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007030 ! Golgi organization +is_a: GO:1903008 ! organelle disassembly +relationship: part_of GO:0048313 ! Golgi inheritance +created_by: tb +creation_date: 2009-12-08T09:15:11Z + +[Term] +id: GO:0090167 +name: Golgi distribution to daughter cells +namespace: biological_process +def: "Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007030 ! Golgi organization +is_a: GO:0051645 ! Golgi localization +relationship: part_of GO:0048313 ! Golgi inheritance +created_by: tb +creation_date: 2009-12-08T09:15:11Z + +[Term] +id: GO:0090168 +name: Golgi reassembly +namespace: biological_process +def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007030 ! Golgi organization +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0048313 ! Golgi inheritance +created_by: tb +creation_date: 2009-12-08T09:15:11Z + +[Term] +id: GO:0090169 +name: regulation of spindle assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of spindle formation" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090224 ! regulation of spindle organization +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051225 ! spindle assembly +relationship: regulates GO:0051225 ! spindle assembly +created_by: tb +creation_date: 2009-12-11T10:17:51Z + +[Term] +id: GO:0090170 +name: regulation of Golgi inheritance +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:1903358 ! regulation of Golgi organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048313 ! Golgi inheritance +relationship: regulates GO:0048313 ! Golgi inheritance +created_by: tb +creation_date: 2009-12-11T10:21:59Z + +[Term] +id: GO:0090171 +name: chondrocyte morphogenesis +namespace: biological_process +def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +relationship: part_of GO:0002063 ! chondrocyte development +created_by: tb +creation_date: 2009-12-11T10:36:02Z + +[Term] +id: GO:0090172 +name: microtubule cytoskeleton organization involved in homologous chromosome segregation +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "microtubule cytoskeleton organisation involved in homologous chromosome segregation" EXACT [GOC:mah] +synonym: "microtubule organization involved in chromosome pairing" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: part_of GO:0045143 ! homologous chromosome segregation +relationship: part_of GO:0045143 ! homologous chromosome segregation +created_by: tb +creation_date: 2009-12-11T11:07:42Z + +[Term] +id: GO:0090173 +name: regulation of synaptonemal complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0060629 ! regulation of homologous chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007130 ! synaptonemal complex assembly +relationship: regulates GO:0007130 ! synaptonemal complex assembly +created_by: tb +creation_date: 2009-12-11T11:40:36Z + +[Term] +id: GO:0090174 +name: organelle membrane fusion +namespace: biological_process +def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048284 ! organelle fusion +is_a: GO:0061025 ! membrane fusion +created_by: tb +creation_date: 2009-12-11T11:44:58Z + +[Term] +id: GO:0090175 +name: regulation of establishment of planar polarity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001736 ! establishment of planar polarity +relationship: regulates GO:0001736 ! establishment of planar polarity +created_by: tb +creation_date: 2009-12-14T10:29:41Z + +[Term] +id: GO:0090176 +name: microtubule cytoskeleton organization involved in establishment of planar polarity +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "microtubule cytoskeleton organisation involved in establishment of planar polarity" EXACT [GOC:mah] +is_a: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: part_of GO:0001736 ! establishment of planar polarity +relationship: part_of GO:0001736 ! establishment of planar polarity +created_by: tb +creation_date: 2009-12-14T10:34:25Z + +[Term] +id: GO:0090177 +name: establishment of planar polarity involved in neural tube closure +namespace: biological_process +def: "Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0042249 ! establishment of planar polarity of embryonic epithelium +is_a: GO:0048598 ! embryonic morphogenesis +intersection_of: GO:0001736 ! establishment of planar polarity +intersection_of: part_of GO:0001843 ! neural tube closure +relationship: part_of GO:0001843 ! neural tube closure +created_by: tb +creation_date: 2009-12-14T10:38:46Z + +[Term] +id: GO:0090178 +name: regulation of establishment of planar polarity involved in neural tube closure +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:0090175 ! regulation of establishment of planar polarity +is_a: GO:1905276 ! regulation of epithelial tube formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090177 ! establishment of planar polarity involved in neural tube closure +relationship: regulates GO:0090177 ! establishment of planar polarity involved in neural tube closure +created_by: tb +creation_date: 2009-12-14T11:14:27Z + +[Term] +id: GO:0090179 +name: planar cell polarity pathway involved in neural tube closure +namespace: biological_process +def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +is_a: GO:0090178 ! regulation of establishment of planar polarity involved in neural tube closure +intersection_of: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: part_of GO:0001843 ! neural tube closure +relationship: part_of GO:0001843 ! neural tube closure +created_by: tb +creation_date: 2009-12-14T11:20:27Z + +[Term] +id: GO:0090180 +name: positive regulation of thiamine biosynthetic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine." [GOC:dph, GOC:tb] +synonym: "positive regulation of thiamin biosynthetic process" EXACT [] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046136 ! positive regulation of vitamin metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0070623 ! regulation of thiamine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009228 ! thiamine biosynthetic process +relationship: positively_regulates GO:0009228 ! thiamine biosynthetic process +created_by: tb +creation_date: 2009-12-18T10:30:07Z + +[Term] +id: GO:0090181 +name: regulation of cholesterol metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008203 ! cholesterol metabolic process +relationship: regulates GO:0008203 ! cholesterol metabolic process +created_by: tb +creation_date: 2009-12-18T10:33:49Z + +[Term] +id: GO:0090182 +name: regulation of secretion of lysosomal enzymes +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033299 ! secretion of lysosomal enzymes +relationship: regulates GO:0033299 ! secretion of lysosomal enzymes +created_by: tb +creation_date: 2009-12-18T10:40:46Z + +[Term] +id: GO:0090183 +name: regulation of kidney development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] +synonym: "regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001822 ! kidney development +relationship: regulates GO:0001822 ! kidney development +created_by: tb +creation_date: 2009-12-18T10:50:56Z + +[Term] +id: GO:0090184 +name: positive regulation of kidney development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] +synonym: "positive regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001822 ! kidney development +relationship: positively_regulates GO:0001822 ! kidney development +created_by: tb +creation_date: 2009-12-18T10:52:01Z + +[Term] +id: GO:0090185 +name: negative regulation of kidney development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] +synonym: "negative regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001822 ! kidney development +relationship: negatively_regulates GO:0001822 ! kidney development +created_by: tb +creation_date: 2009-12-18T10:58:45Z + +[Term] +id: GO:0090186 +name: regulation of pancreatic juice secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine." [GOC:dph, GOC:tb] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0050878 ! regulation of body fluid levels +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030157 ! pancreatic juice secretion +relationship: regulates GO:0030157 ! pancreatic juice secretion +created_by: tb +creation_date: 2009-12-18T11:03:24Z + +[Term] +id: GO:0090187 +name: positive regulation of pancreatic juice secretion +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0060456 ! positive regulation of digestive system process +is_a: GO:0090186 ! regulation of pancreatic juice secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030157 ! pancreatic juice secretion +relationship: positively_regulates GO:0030157 ! pancreatic juice secretion +created_by: tb +creation_date: 2009-12-18T11:03:24Z + +[Term] +id: GO:0090188 +name: negative regulation of pancreatic juice secretion +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0060457 ! negative regulation of digestive system process +is_a: GO:0090186 ! regulation of pancreatic juice secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030157 ! pancreatic juice secretion +relationship: negatively_regulates GO:0030157 ! pancreatic juice secretion +created_by: tb +creation_date: 2009-12-18T11:03:24Z + +[Term] +id: GO:0090189 +name: regulation of branching involved in ureteric bud morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: tb +creation_date: 2009-12-18T11:11:17Z + +[Term] +id: GO:0090190 +name: positive regulation of branching involved in ureteric bud morphogenesis +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: tb +creation_date: 2009-12-18T11:11:17Z + +[Term] +id: GO:0090191 +name: negative regulation of branching involved in ureteric bud morphogenesis +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +relationship: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis +created_by: tb +creation_date: 2009-12-18T11:11:17Z + +[Term] +id: GO:0090192 +name: regulation of glomerulus development +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032835 ! glomerulus development +relationship: regulates GO:0032835 ! glomerulus development +created_by: tb +creation_date: 2009-12-18T11:17:13Z + +[Term] +id: GO:0090193 +name: positive regulation of glomerulus development +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:0090192 ! regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032835 ! glomerulus development +relationship: positively_regulates GO:0032835 ! glomerulus development +created_by: tb +creation_date: 2009-12-18T11:17:13Z + +[Term] +id: GO:0090194 +name: negative regulation of glomerulus development +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:0090192 ! regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032835 ! glomerulus development +relationship: negatively_regulates GO:0032835 ! glomerulus development +created_by: tb +creation_date: 2009-12-18T11:17:13Z + +[Term] +id: GO:0090195 +name: chemokine secretion +namespace: biological_process +def: "The regulated release of chemokines from a cell." [GOC:BHF, GOC:rl] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032602 ! chemokine production +created_by: tb +creation_date: 2009-12-18T11:26:20Z + +[Term] +id: GO:0090196 +name: regulation of chemokine secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell." [GOC:BHF, GOC:rl] +is_a: GO:0032642 ! regulation of chemokine production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090195 ! chemokine secretion +relationship: regulates GO:0090195 ! chemokine secretion +created_by: tb +creation_date: 2009-12-18T11:28:00Z + +[Term] +id: GO:0090197 +name: positive regulation of chemokine secretion +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell." [GOC:BHF, GOC:rl] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0090196 ! regulation of chemokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090195 ! chemokine secretion +relationship: positively_regulates GO:0090195 ! chemokine secretion +created_by: tb +creation_date: 2009-12-18T11:28:00Z + +[Term] +id: GO:0090198 +name: negative regulation of chemokine secretion +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell." [GOC:BHF, GOC:rl] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0090196 ! regulation of chemokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090195 ! chemokine secretion +relationship: negatively_regulates GO:0090195 ! chemokine secretion +created_by: tb +creation_date: 2009-12-18T11:28:00Z + +[Term] +id: GO:0090199 +name: regulation of release of cytochrome c from mitochondria +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] +comment: The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly regulate this process. +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001836 ! release of cytochrome c from mitochondria +relationship: regulates GO:0001836 ! release of cytochrome c from mitochondria +created_by: tb +creation_date: 2009-12-18T11:35:20Z + +[Term] +id: GO:0090200 +name: positive regulation of release of cytochrome c from mitochondria +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +comment: The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and positively regulate this process. +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0090199 ! regulation of release of cytochrome c from mitochondria +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001836 ! release of cytochrome c from mitochondria +relationship: positively_regulates GO:0001836 ! release of cytochrome c from mitochondria +created_by: tb +creation_date: 2009-12-18T11:35:20Z + +[Term] +id: GO:0090201 +name: negative regulation of release of cytochrome c from mitochondria +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] +comment: The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and negatively regulate this process. +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0090199 ! regulation of release of cytochrome c from mitochondria +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001836 ! release of cytochrome c from mitochondria +relationship: negatively_regulates GO:0001836 ! release of cytochrome c from mitochondria +created_by: tb +creation_date: 2009-12-18T11:35:20Z + +[Term] +id: GO:0090202 +name: gene looping +namespace: biological_process +def: "The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes." [GOC:dph, GOC:rb, GOC:tb, PMID:19923429, PMID:19933150] +is_a: GO:0006325 ! chromatin organization +is_a: GO:0090579 ! dsDNA loop formation +created_by: tb +creation_date: 2009-12-18T11:56:00Z + +[Term] +id: GO:0090203 +name: transcriptional activation by promoter-terminator looping +namespace: biological_process +def: "The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter." [GOC:dph, GOC:rb, GOC:tb] +synonym: "transcriptional activation by memory gene loops" RELATED [GOC:dph, GOC:rb, GOC:tb] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0090202 ! gene looping +created_by: tb +creation_date: 2009-12-18T11:58:32Z + +[Term] +id: GO:0090204 +name: protein localization to nuclear pore +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a nuclear pore." [GOC:dph, GOC:rb, GOC:tb] +synonym: "protein localisation to nuclear pore" EXACT [GOC:mah] +is_a: GO:0090435 ! protein localization to nuclear envelope +created_by: tb +creation_date: 2009-12-18T12:05:01Z + +[Term] +id: GO:0090205 +name: positive regulation of cholesterol metabolic process +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0045940 ! positive regulation of steroid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:0090181 ! regulation of cholesterol metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008203 ! cholesterol metabolic process +relationship: positively_regulates GO:0008203 ! cholesterol metabolic process +created_by: tb +creation_date: 2009-12-23T10:27:37Z + +[Term] +id: GO:0090206 +name: negative regulation of cholesterol metabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0045939 ! negative regulation of steroid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0090181 ! regulation of cholesterol metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008203 ! cholesterol metabolic process +relationship: negatively_regulates GO:0008203 ! cholesterol metabolic process +created_by: tb +creation_date: 2009-12-23T10:27:37Z + +[Term] +id: GO:0090207 +name: regulation of triglyceride metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006641 ! triglyceride metabolic process +relationship: regulates GO:0006641 ! triglyceride metabolic process +created_by: tb +creation_date: 2009-12-23T10:35:06Z + +[Term] +id: GO:0090208 +name: positive regulation of triglyceride metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045834 ! positive regulation of lipid metabolic process +is_a: GO:0090207 ! regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006641 ! triglyceride metabolic process +relationship: positively_regulates GO:0006641 ! triglyceride metabolic process +created_by: tb +creation_date: 2009-12-23T10:35:06Z + +[Term] +id: GO:0090209 +name: negative regulation of triglyceride metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0090207 ! regulation of triglyceride metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006641 ! triglyceride metabolic process +relationship: negatively_regulates GO:0006641 ! triglyceride metabolic process +created_by: tb +creation_date: 2009-12-23T10:35:06Z + +[Term] +id: GO:0090210 +name: regulation of establishment of blood-brain barrier +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain." [GOC:dph, GOC:tb] +synonym: "regulation of establishment of BBB" EXACT [PMID:20080302] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060856 ! establishment of blood-brain barrier +relationship: regulates GO:0060856 ! establishment of blood-brain barrier +created_by: tb +creation_date: 2009-12-23T12:15:53Z + +[Term] +id: GO:0090211 +name: positive regulation of establishment of blood-brain barrier +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain." [GOC:BHF, GOC:dph, GOC:tb] +synonym: "positive regulation of establishment of BBB" EXACT [PMID:20080302] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:0090210 ! regulation of establishment of blood-brain barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060856 ! establishment of blood-brain barrier +relationship: positively_regulates GO:0060856 ! establishment of blood-brain barrier +created_by: tb +creation_date: 2009-12-23T12:15:53Z + +[Term] +id: GO:0090212 +name: negative regulation of establishment of blood-brain barrier +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain." [GOC:dph, GOC:tb] +synonym: "negative regulation of establishment of BBB" EXACT [PMID:20080302] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:0090210 ! regulation of establishment of blood-brain barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060856 ! establishment of blood-brain barrier +relationship: negatively_regulates GO:0060856 ! establishment of blood-brain barrier +created_by: tb +creation_date: 2009-12-23T12:15:53Z + +[Term] +id: GO:0090213 +name: regulation of radial pattern formation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur." [GOC:tb] +synonym: "regulation of radial pattern specification" NARROW [GOC:tb] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009956 ! radial pattern formation +relationship: regulates GO:0009956 ! radial pattern formation +created_by: tb +creation_date: 2010-01-05T10:59:10Z + +[Term] +id: GO:0090214 +name: spongiotrophoblast layer developmental growth +namespace: biological_process +def: "The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state." [GOC:dph, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0048589 ! developmental growth +relationship: part_of GO:0060712 ! spongiotrophoblast layer development +created_by: tb +creation_date: 2010-01-08T12:10:44Z + +[Term] +id: GO:0090215 +name: regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GOC:dph, GOC:tb] +is_a: GO:0043550 ! regulation of lipid kinase activity +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +relationship: regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +created_by: tb +creation_date: 2010-01-12T10:00:45Z + +[Term] +id: GO:0090216 +name: positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GOC:dph, GOC:tb] +is_a: GO:0090215 ! regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +is_a: GO:0090218 ! positive regulation of lipid kinase activity +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +relationship: positively_regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +created_by: tb +creation_date: 2010-01-12T10:00:45Z + +[Term] +id: GO:0090217 +name: negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GOC:dph, GOC:tb] +is_a: GO:0090215 ! regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +is_a: GO:0090219 ! negative regulation of lipid kinase activity +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +relationship: negatively_regulates GO:0016308 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity +created_by: tb +creation_date: 2010-01-12T10:00:45Z + +[Term] +id: GO:0090218 +name: positive regulation of lipid kinase activity +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." [GOC:dph, GOC:tb] +is_a: GO:0033674 ! positive regulation of kinase activity +is_a: GO:0043550 ! regulation of lipid kinase activity +is_a: GO:0045834 ! positive regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001727 ! lipid kinase activity +relationship: positively_regulates GO:0001727 ! lipid kinase activity +created_by: tb +creation_date: 2010-01-12T10:18:30Z + +[Term] +id: GO:0090219 +name: negative regulation of lipid kinase activity +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." [GOC:dph, GOC:tb] +is_a: GO:0033673 ! negative regulation of kinase activity +is_a: GO:0043550 ! regulation of lipid kinase activity +is_a: GO:0045833 ! negative regulation of lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001727 ! lipid kinase activity +relationship: negatively_regulates GO:0001727 ! lipid kinase activity +created_by: tb +creation_date: 2010-01-12T10:18:30Z + +[Term] +id: GO:0090220 +name: chromosome localization to nuclear envelope involved in homologous chromosome segregation +namespace: biological_process +def: "The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:19913287] +synonym: "chromosome localisation to nuclear envelope involved in homologous chromosome segregation" EXACT [GOC:mah] +is_a: GO:0051303 ! establishment of chromosome localization +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0045143 ! homologous chromosome segregation +created_by: tb +creation_date: 2010-01-13T10:20:33Z + +[Term] +id: GO:0090221 +name: mitotic spindle-templated microtubule nucleation +namespace: biological_process +def: "The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007020 ! microtubule nucleation +created_by: tb +creation_date: 2010-01-13T10:42:37Z + +[Term] +id: GO:0090222 +name: centrosome-templated microtubule nucleation +namespace: biological_process +def: "The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0051418 ! microtubule nucleation by microtubule organizing center +created_by: tb +creation_date: 2010-01-13T10:52:36Z + +[Term] +id: GO:0090223 +name: chromatin-templated microtubule nucleation +namespace: biological_process +def: "The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0007020 ! microtubule nucleation +created_by: tb +creation_date: 2010-01-13T10:53:35Z + +[Term] +id: GO:0090224 +name: regulation of spindle organization +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of spindle organisation" EXACT [GOC:mah] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007051 ! spindle organization +relationship: regulates GO:0007051 ! spindle organization +created_by: tb +creation_date: 2010-01-13T11:04:53Z + +[Term] +id: GO:0090225 +name: regulation of spindle density +namespace: biological_process +def: "Any process that modulates the number of microtubules in a given region of the spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0090224 ! regulation of spindle organization +created_by: tb +creation_date: 2010-01-13T11:24:53Z + +[Term] +id: GO:0090226 +name: regulation of microtubule nucleation by Ran protein signal transduction +namespace: biological_process +def: "Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010968 ! regulation of microtubule nucleation +is_a: GO:0031291 ! Ran protein signal transduction +intersection_of: GO:0031291 ! Ran protein signal transduction +intersection_of: regulates GO:0007020 ! microtubule nucleation +created_by: tb +creation_date: 2010-01-13T11:35:31Z + +[Term] +id: GO:0090227 +name: regulation of red or far-red light signaling pathway +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light." [GOC:tb] +synonym: "regulation of phytochrome signaling pathway" EXACT [GOC:tb] +synonym: "regulation of red or far-red light signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:2000030 ! regulation of response to red or far red light +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010017 ! red or far-red light signaling pathway +relationship: regulates GO:0010017 ! red or far-red light signaling pathway +created_by: tb +creation_date: 2010-01-19T04:03:29Z + +[Term] +id: GO:0090228 +name: positive regulation of red or far-red light signaling pathway +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light." [GOC:tb] +synonym: "positive regulation of phytochrome signaling pathway" EXACT [GOC:tb] +synonym: "positive regulation of red or far-red light signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0090227 ! regulation of red or far-red light signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010017 ! red or far-red light signaling pathway +relationship: positively_regulates GO:0010017 ! red or far-red light signaling pathway +created_by: tb +creation_date: 2010-01-19T04:03:29Z + +[Term] +id: GO:0090229 +name: negative regulation of red or far-red light signaling pathway +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light." [GOC:tb] +synonym: "negative regulation of phytochrome signaling pathway" EXACT [GOC:tb] +synonym: "negative regulation of red or far-red light signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0090227 ! regulation of red or far-red light signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010017 ! red or far-red light signaling pathway +relationship: negatively_regulates GO:0010017 ! red or far-red light signaling pathway +created_by: tb +creation_date: 2010-01-19T04:03:29Z + +[Term] +id: GO:0090230 +name: regulation of centromere complex assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "centromere licensing" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034508 ! centromere complex assembly +relationship: regulates GO:0034508 ! centromere complex assembly +created_by: tb +creation_date: 2010-01-20T10:20:49Z + +[Term] +id: GO:0090231 +name: regulation of spindle checkpoint +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc). +subset: gocheck_do_not_manually_annotate +is_a: GO:1901976 ! regulation of cell cycle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031577 ! spindle checkpoint +relationship: regulates GO:0031577 ! spindle checkpoint +created_by: tb +creation_date: 2010-01-20T10:29:43Z + +[Term] +id: GO:0090232 +name: positive regulation of spindle checkpoint +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +subset: gocheck_do_not_manually_annotate +synonym: "spindle checkpoint activation" NARROW [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090231 ! regulation of spindle checkpoint +is_a: GO:1901978 ! positive regulation of cell cycle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031577 ! spindle checkpoint +relationship: positively_regulates GO:0031577 ! spindle checkpoint +created_by: tb +creation_date: 2010-01-20T10:29:43Z + +[Term] +id: GO:0090233 +name: negative regulation of spindle checkpoint +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc). +subset: gocheck_do_not_manually_annotate +synonym: "spindle checkpoint silencing" NARROW [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090231 ! regulation of spindle checkpoint +is_a: GO:1901977 ! negative regulation of cell cycle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031577 ! spindle checkpoint +relationship: negatively_regulates GO:0031577 ! spindle checkpoint +created_by: tb +creation_date: 2010-01-20T10:29:43Z + +[Term] +id: GO:0090234 +name: regulation of kinetochore assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of chromosome-kinetochore attachment" NARROW [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090230 ! regulation of centromere complex assembly +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051382 ! kinetochore assembly +relationship: regulates GO:0051382 ! kinetochore assembly +created_by: tb +creation_date: 2010-01-20T10:46:56Z + +[Term] +id: GO:0090235 +name: regulation of metaphase plate congression +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "regulation of chromosome congression" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051983 ! regulation of chromosome segregation +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051310 ! metaphase plate congression +relationship: regulates GO:0051310 ! metaphase plate congression +created_by: tb +creation_date: 2010-01-20T11:05:55Z + +[Term] +id: GO:0090236 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in somitogenesis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:ascb_2009, GOC:dph, GOC:tb] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: tb +creation_date: 2010-01-20T11:12:29Z + +[Term] +id: GO:0090237 +name: regulation of arachidonic acid secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue." [GOC:dph, GOC:tb] +is_a: GO:0032303 ! regulation of icosanoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050482 ! arachidonic acid secretion +relationship: regulates GO:0050482 ! arachidonic acid secretion +created_by: tb +creation_date: 2010-01-20T03:32:22Z + +[Term] +id: GO:0090238 +name: positive regulation of arachidonic acid secretion +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0032305 ! positive regulation of icosanoid secretion +is_a: GO:0090237 ! regulation of arachidonic acid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050482 ! arachidonic acid secretion +relationship: positively_regulates GO:0050482 ! arachidonic acid secretion +created_by: tb +creation_date: 2010-01-20T03:32:22Z + +[Term] +id: GO:0090239 +name: regulation of histone H4 acetylation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group." [GOC:dph, GOC:tb] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043967 ! histone H4 acetylation +relationship: regulates GO:0043967 ! histone H4 acetylation +created_by: tb +creation_date: 2010-01-20T03:48:09Z + +[Term] +id: GO:0090240 +name: positive regulation of histone H4 acetylation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group." [GOC:dph, GOC:tb] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:0090239 ! regulation of histone H4 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043967 ! histone H4 acetylation +relationship: positively_regulates GO:0043967 ! histone H4 acetylation +created_by: tb +creation_date: 2010-01-20T03:48:09Z + +[Term] +id: GO:0090241 +name: negative regulation of histone H4 acetylation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group." [GOC:dph, GOC:tb] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:0090239 ! regulation of histone H4 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043967 ! histone H4 acetylation +relationship: negatively_regulates GO:0043967 ! histone H4 acetylation +created_by: tb +creation_date: 2010-01-20T03:48:09Z + +[Term] +id: GO:0090242 +name: retinoic acid receptor signaling pathway involved in somitogenesis +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "retinoic acid receptor signalling pathway involved in somitogenesis" EXACT [GOC:mah] +is_a: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: GO:0048384 ! retinoic acid receptor signaling pathway +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0001756 ! somitogenesis +created_by: tb +creation_date: 2010-01-22T10:42:54Z + +[Term] +id: GO:0090243 +name: fibroblast growth factor receptor signaling pathway involved in somitogenesis +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "fibroblast growth factor receptor signalling pathway involved in somitogenesis" EXACT [GOC:mah] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0001756 ! somitogenesis +created_by: tb +creation_date: 2010-01-22T10:46:15Z + +[Term] +id: GO:0090244 +name: Wnt signaling pathway involved in somitogenesis +namespace: biological_process +def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "Wnt receptor signaling pathway involved in somitogenesis" EXACT [] +synonym: "Wnt receptor signalling" EXACT [GOC:mah] +synonym: "Wnt-activated signaling pathway involved in somitogenesis" EXACT [GOC:signaling] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0001756 ! somitogenesis +created_by: tb +creation_date: 2010-01-22T10:47:59Z + +[Term] +id: GO:0090245 +name: axis elongation involved in somitogenesis +namespace: biological_process +def: "The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0003401 ! axis elongation +intersection_of: GO:0003401 ! axis elongation +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0001756 ! somitogenesis +created_by: tb +creation_date: 2010-01-22T10:54:29Z + +[Term] +id: GO:0090246 +name: convergent extension involved in somitogenesis +namespace: biological_process +def: "The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0060027 ! convergent extension involved in gastrulation +is_a: GO:0060028 ! convergent extension involved in axis elongation +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0090245 ! axis elongation involved in somitogenesis +created_by: tb +creation_date: 2010-01-22T10:59:06Z + +[Term] +id: GO:0090247 +name: cell motility involved in somitogenic axis elongation +namespace: biological_process +def: "Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0048870 ! cell motility +intersection_of: GO:0048870 ! cell motility +intersection_of: part_of GO:0090245 ! axis elongation involved in somitogenesis +relationship: part_of GO:0090245 ! axis elongation involved in somitogenesis +created_by: tb +creation_date: 2010-01-22T11:07:17Z + +[Term] +id: GO:0090248 +name: cell migration involved in somitogenic axis elongation +namespace: biological_process +def: "The orderly movement of a presomitic mesoderm cell that contributes to somitogenic axis elongation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0016477 ! cell migration +is_a: GO:0090247 ! cell motility involved in somitogenic axis elongation +intersection_of: GO:0016477 ! cell migration +intersection_of: part_of GO:0090245 ! axis elongation involved in somitogenesis +created_by: tb +creation_date: 2010-01-22T11:13:59Z + +[Term] +id: GO:0090249 +name: regulation of cell motility involved in somitogenic axis elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0014807 ! regulation of somitogenesis +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090247 ! cell motility involved in somitogenic axis elongation +relationship: regulates GO:0090247 ! cell motility involved in somitogenic axis elongation +created_by: tb +creation_date: 2010-01-22T11:20:05Z + +[Term] +id: GO:0090250 +name: cell-cell adhesion involved in establishment of planar polarity +namespace: biological_process +def: "The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +intersection_of: part_of GO:0001736 ! establishment of planar polarity +relationship: part_of GO:0001736 ! establishment of planar polarity +created_by: tb +creation_date: 2010-01-22T11:28:03Z + +[Term] +id: GO:0090251 +name: protein localization involved in establishment of planar polarity +namespace: biological_process +def: "Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity." [GOC:ascb_2009, GOC:dph, GOC:tb] +synonym: "protein localisation involved in establishment of planar polarity" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +intersection_of: GO:0008104 ! protein localization +intersection_of: part_of GO:0001736 ! establishment of planar polarity +relationship: part_of GO:0001736 ! establishment of planar polarity +created_by: tb +creation_date: 2010-01-22T11:31:32Z + +[Term] +id: GO:0090252 +name: epithelium migration involved in imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0090132 ! epithelium migration +intersection_of: GO:0090132 ! epithelium migration +intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +created_by: tb +creation_date: 2010-01-22T11:40:46Z + +[Term] +id: GO:0090253 +name: convergent extension involved in imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0009886 ! post-embryonic animal morphogenesis +is_a: GO:0060029 ! convergent extension involved in organogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +created_by: tb +creation_date: 2010-01-22T11:40:46Z + +[Term] +id: GO:0090254 +name: cell elongation involved in imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0009826 ! unidimensional cell growth +is_a: GO:0009886 ! post-embryonic animal morphogenesis +intersection_of: GO:0009826 ! unidimensional cell growth +intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +created_by: tb +creation_date: 2010-01-22T11:40:46Z + +[Term] +id: GO:0090255 +name: cell proliferation involved in imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0008283 ! cell population proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +created_by: tb +creation_date: 2010-01-22T11:40:46Z + +[Term] +id: GO:0090256 +name: regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis." [GOC:ascb_2009, GOC:dph, GOC:tb] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0042127 ! regulation of cell population proliferation +intersection_of: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: part_of GO:0007476 ! imaginal disc-derived wing morphogenesis +relationship: regulates GO:0090255 ! cell proliferation involved in imaginal disc-derived wing morphogenesis +created_by: tb +creation_date: 2010-01-22T11:40:46Z + +[Term] +id: GO:0090257 +name: regulation of muscle system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003012 ! muscle system process +relationship: regulates GO:0003012 ! muscle system process +created_by: tb +creation_date: 2010-02-03T11:48:13Z + +[Term] +id: GO:0090258 +name: negative regulation of mitochondrial fission +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." [GOC:sl, GOC:tb] +synonym: "negative regulation of mitochondrial division" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0090140 ! regulation of mitochondrial fission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000266 ! mitochondrial fission +relationship: negatively_regulates GO:0000266 ! mitochondrial fission +created_by: tb +creation_date: 2010-02-03T04:05:32Z + +[Term] +id: GO:0090259 +name: regulation of retinal ganglion cell axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:tb, GOC:yaf] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031290 ! retinal ganglion cell axon guidance +relationship: regulates GO:0031290 ! retinal ganglion cell axon guidance +created_by: tb +creation_date: 2010-02-03T04:13:59Z + +[Term] +id: GO:0090260 +name: negative regulation of retinal ganglion cell axon guidance +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues." [GOC:tb, GOC:yaf] +comment: Note that growth cone collapse has been observed only in assays performed in vitro. +synonym: "axon growth cone collapse" RELATED [] +is_a: GO:0090259 ! regulation of retinal ganglion cell axon guidance +is_a: GO:1902668 ! negative regulation of axon guidance +intersection_of: GO:0048519 ! negative regulation of biological process +intersection_of: negatively_regulates GO:0031290 ! retinal ganglion cell axon guidance +relationship: negatively_regulates GO:0031290 ! retinal ganglion cell axon guidance +created_by: tb +creation_date: 2010-02-03T04:13:59Z + +[Term] +id: GO:0090261 +name: positive regulation of inclusion body assembly +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body." [GOC:tb] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0090083 ! regulation of inclusion body assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070841 ! inclusion body assembly +relationship: positively_regulates GO:0070841 ! inclusion body assembly +created_by: tb +creation_date: 2010-02-03T04:23:54Z + +[Term] +id: GO:0090262 +name: regulation of transcription-coupled nucleotide-excision repair +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway." [GOC:tb] +is_a: GO:2000819 ! regulation of nucleotide-excision repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006283 ! transcription-coupled nucleotide-excision repair +relationship: regulates GO:0006283 ! transcription-coupled nucleotide-excision repair +created_by: tb +creation_date: 2010-02-03T04:27:42Z + +[Term] +id: GO:0090263 +name: positive regulation of canonical Wnt signaling pathway +namespace: biological_process +alt_id: GO:0035413 +def: "Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes." [GOC:tb] +synonym: "positive regulation of canonical Wnt receptor signaling pathway" EXACT [] +synonym: "positive regulation of canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "positive regulation of catenin import into nucleus" NARROW [] +synonym: "positive regulation of catenin protein nuclear translocation" NARROW [GOC:mah] +synonym: "positive regulation of Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:mtg_signal] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060070 ! canonical Wnt signaling pathway +relationship: positively_regulates GO:0060070 ! canonical Wnt signaling pathway +created_by: tb +creation_date: 2010-02-03T04:32:16Z + +[Term] +id: GO:0090264 +name: regulation of immune complex clearance by monocytes and macrophages +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages." [GOC:tb] +is_a: GO:0002697 ! regulation of immune effector process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002436 ! immune complex clearance by monocytes and macrophages +relationship: regulates GO:0002436 ! immune complex clearance by monocytes and macrophages +created_by: tb +creation_date: 2010-02-04T04:31:29Z + +[Term] +id: GO:0090265 +name: positive regulation of immune complex clearance by monocytes and macrophages +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages." [GOC:BHF] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0090264 ! regulation of immune complex clearance by monocytes and macrophages +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002436 ! immune complex clearance by monocytes and macrophages +relationship: positively_regulates GO:0002436 ! immune complex clearance by monocytes and macrophages +created_by: tb +creation_date: 2010-02-04T04:32:18Z + +[Term] +id: GO:0090266 +name: regulation of mitotic cell cycle spindle assembly checkpoint +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mtg_cell_cycle] +is_a: GO:0030071 ! regulation of mitotic metaphase/anaphase transition +is_a: GO:1903504 ! regulation of mitotic spindle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007094 ! mitotic spindle assembly checkpoint +relationship: regulates GO:0007094 ! mitotic spindle assembly checkpoint +created_by: tb +creation_date: 2010-02-05T02:06:37Z + +[Term] +id: GO:0090267 +name: positive regulation of mitotic cell cycle spindle assembly checkpoint +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mah, GOC:vw] +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:0090232 ! positive regulation of spindle checkpoint +is_a: GO:0090266 ! regulation of mitotic cell cycle spindle assembly checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007094 ! mitotic spindle assembly checkpoint +relationship: positively_regulates GO:0007094 ! mitotic spindle assembly checkpoint +created_by: tb +creation_date: 2010-02-05T02:09:44Z + +[Term] +id: GO:0090268 +name: activation of mitotic cell cycle spindle assembly checkpoint +namespace: biological_process +def: "Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint." [GOC:mah, GOC:vw] +is_a: GO:0090267 ! positive regulation of mitotic cell cycle spindle assembly checkpoint +created_by: tb +creation_date: 2010-02-05T02:09:44Z + +[Term] +id: GO:0090269 +name: fibroblast growth factor production +namespace: biological_process +def: "The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001816 ! cytokine production +created_by: tb +creation_date: 2010-02-05T02:33:33Z + +[Term] +id: GO:0090270 +name: regulation of fibroblast growth factor production +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001816 ! cytokine production +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090269 ! fibroblast growth factor production +relationship: regulates GO:0090269 ! fibroblast growth factor production +created_by: tb +creation_date: 2010-02-05T02:33:33Z + +[Term] +id: GO:0090271 +name: positive regulation of fibroblast growth factor production +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0090270 ! regulation of fibroblast growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090269 ! fibroblast growth factor production +relationship: positively_regulates GO:0090269 ! fibroblast growth factor production +created_by: tb +creation_date: 2010-02-05T02:33:33Z + +[Term] +id: GO:0090272 +name: negative regulation of fibroblast growth factor production +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0090270 ! regulation of fibroblast growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090269 ! fibroblast growth factor production +relationship: negatively_regulates GO:0090269 ! fibroblast growth factor production +created_by: tb +creation_date: 2010-02-05T02:33:33Z + +[Term] +id: GO:0090273 +name: regulation of somatostatin secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070253 ! somatostatin secretion +relationship: regulates GO:0070253 ! somatostatin secretion +created_by: tb +creation_date: 2010-02-05T02:54:14Z + +[Term] +id: GO:0090274 +name: positive regulation of somatostatin secretion +namespace: biological_process +def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] +is_a: GO:0090273 ! regulation of somatostatin secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070253 ! somatostatin secretion +relationship: positively_regulates GO:0070253 ! somatostatin secretion +created_by: tb +creation_date: 2010-02-05T02:54:14Z + +[Term] +id: GO:0090275 +name: negative regulation of somatostatin secretion +namespace: biological_process +def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] +is_a: GO:0090273 ! regulation of somatostatin secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070253 ! somatostatin secretion +relationship: negatively_regulates GO:0070253 ! somatostatin secretion +created_by: tb +creation_date: 2010-02-05T02:54:14Z + +[Term] +id: GO:0090276 +name: regulation of peptide hormone secretion +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] +is_a: GO:0002791 ! regulation of peptide secretion +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030072 ! peptide hormone secretion +relationship: regulates GO:0030072 ! peptide hormone secretion +created_by: tb +creation_date: 2010-02-05T02:56:39Z + +[Term] +id: GO:0090277 +name: positive regulation of peptide hormone secretion +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] +is_a: GO:0002793 ! positive regulation of peptide secretion +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030072 ! peptide hormone secretion +relationship: positively_regulates GO:0030072 ! peptide hormone secretion +created_by: tb +creation_date: 2010-02-05T02:56:39Z + +[Term] +id: GO:0090278 +name: negative regulation of peptide hormone secretion +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] +is_a: GO:0002792 ! negative regulation of peptide secretion +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030072 ! peptide hormone secretion +relationship: negatively_regulates GO:0030072 ! peptide hormone secretion +created_by: tb +creation_date: 2010-02-05T02:56:39Z + +[Term] +id: GO:0090279 +name: regulation of calcium ion import +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051924 ! regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070509 ! calcium ion import +relationship: regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + +[Term] +id: GO:0090280 +name: positive regulation of calcium ion import +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "positive regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051928 ! positive regulation of calcium ion transport +is_a: GO:0090279 ! regulation of calcium ion import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070509 ! calcium ion import +relationship: positively_regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + +[Term] +id: GO:0090281 +name: negative regulation of calcium ion import +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "negative regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051926 ! negative regulation of calcium ion transport +is_a: GO:0090279 ! regulation of calcium ion import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070509 ! calcium ion import +relationship: negatively_regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + +[Term] +id: GO:0090282 +name: positive regulation of transcription involved in G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle." [GOC:rn, PMID:10747051, PMID:10894548, PMID:10899128, PMID:10959837] +synonym: "activation of G2/M-specific transcription in the mitotic cell cycle" EXACT [GOC:rn] +synonym: "activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle" EXACT [GOC:rn] +synonym: "activation of transcription involved in G2/M transition of mitotic cell cycle" EXACT [GOC:rn] +synonym: "positive regulation of G2/M-specific transcription in the mitotic cell cycle" EXACT [GOC:rn] +synonym: "positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle" EXACT [GOC:rn] +synonym: "up-regulation of G2/M-specific transcription in the mitotic cell cycle" EXACT [GOC:rn] +synonym: "up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle" EXACT [GOC:rn] +synonym: "up-regulation of transcription involved in G2/M transition of mitotic cell cycle" EXACT [GOC:rn] +is_a: GO:0000117 ! regulation of transcription involved in G2/M transition of mitotic cell cycle +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045893 ! positive regulation of transcription, DNA-templated +intersection_of: part_of GO:0000086 ! G2/M transition of mitotic cell cycle +created_by: tb +creation_date: 2010-02-09T02:13:26Z + +[Term] +id: GO:0090283 +name: regulation of protein glycosylation in Golgi +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus." [GOC:pr, GOC:tb] +synonym: "regulation of protein amino acid glycosylation in Golgi" EXACT [GOC:bf] +is_a: GO:0060049 ! regulation of protein glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033578 ! protein glycosylation in Golgi +relationship: regulates GO:0033578 ! protein glycosylation in Golgi +created_by: tb +creation_date: 2010-02-18T02:43:55Z + +[Term] +id: GO:0090284 +name: positive regulation of protein glycosylation in Golgi +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus." [GOC:pr, GOC:tb] +synonym: "positive regulation of protein amino acid glycosylation in Golgi" EXACT [GOC:bf] +is_a: GO:0060050 ! positive regulation of protein glycosylation +is_a: GO:0090283 ! regulation of protein glycosylation in Golgi +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033578 ! protein glycosylation in Golgi +relationship: positively_regulates GO:0033578 ! protein glycosylation in Golgi +created_by: tb +creation_date: 2010-02-18T02:43:55Z + +[Term] +id: GO:0090285 +name: negative regulation of protein glycosylation in Golgi +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus." [GOC:pr, GOC:tb] +synonym: "negative regulation of protein amino acid glycosylation in Golgi" EXACT [GOC:bf] +is_a: GO:0060051 ! negative regulation of protein glycosylation +is_a: GO:0090283 ! regulation of protein glycosylation in Golgi +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033578 ! protein glycosylation in Golgi +relationship: negatively_regulates GO:0033578 ! protein glycosylation in Golgi +created_by: tb +creation_date: 2010-02-18T02:43:55Z + +[Term] +id: GO:0090286 +name: obsolete cytoskeletal anchoring at nuclear membrane +namespace: biological_process +def: "OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane." [GOC:tb] +comment: This term was obsoleted because it represented a molecular function. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18283 xsd:anyURI +is_obsolete: true +consider: GO:0140444 +created_by: tb +creation_date: 2010-02-18T02:56:26Z + +[Term] +id: GO:0090287 +name: regulation of cellular response to growth factor stimulus +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." [GOC:tb] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071363 ! cellular response to growth factor stimulus +relationship: regulates GO:0071363 ! cellular response to growth factor stimulus +created_by: tb +creation_date: 2010-02-18T03:01:25Z + +[Term] +id: GO:0090288 +name: negative regulation of cellular response to growth factor stimulus +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." [GOC:BHF] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071363 ! cellular response to growth factor stimulus +relationship: negatively_regulates GO:0071363 ! cellular response to growth factor stimulus +created_by: tb +creation_date: 2010-02-18T03:01:25Z + +[Term] +id: GO:0090289 +name: regulation of osteoclast proliferation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." [GOC:tb] +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002158 ! osteoclast proliferation +relationship: regulates GO:0002158 ! osteoclast proliferation +created_by: tb +creation_date: 2010-02-18T03:11:03Z + +[Term] +id: GO:0090290 +name: positive regulation of osteoclast proliferation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." [GOC:tb] +is_a: GO:0070665 ! positive regulation of leukocyte proliferation +is_a: GO:0090289 ! regulation of osteoclast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002158 ! osteoclast proliferation +relationship: positively_regulates GO:0002158 ! osteoclast proliferation +created_by: tb +creation_date: 2010-02-18T03:11:03Z + +[Term] +id: GO:0090291 +name: negative regulation of osteoclast proliferation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population." [GOC:tb] +is_a: GO:0070664 ! negative regulation of leukocyte proliferation +is_a: GO:0090289 ! regulation of osteoclast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002158 ! osteoclast proliferation +relationship: negatively_regulates GO:0002158 ! osteoclast proliferation +created_by: tb +creation_date: 2010-02-18T03:11:03Z + +[Term] +id: GO:0090292 +name: nuclear matrix anchoring at nuclear membrane +namespace: biological_process +def: "The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane." [GOC:tb] +synonym: "nucleoskeleton anchoring at nuclear membrane" EXACT [GOC:tb] +is_a: GO:0043578 ! nuclear matrix organization +is_a: GO:0051457 ! maintenance of protein location in nucleus +created_by: tb +creation_date: 2010-02-22T03:05:13Z + +[Term] +id: GO:0090293 +name: nitrogen catabolite regulation of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:rb, PMID:19104072] +synonym: "regulation of transcription by nitrogen catabolites" EXACT [GOC:mah] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0006808 ! regulation of nitrogen utilization +is_a: GO:0031670 ! cellular response to nutrient +relationship: part_of GO:0071417 ! cellular response to organonitrogen compound +created_by: tb +creation_date: 2010-02-24T02:31:53Z + +[Term] +id: GO:0090294 +name: nitrogen catabolite activation of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:rb, PMID:19104072] +synonym: "positive regulation of transcription by nitrogen catabolites" EXACT [GOC:mah] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:0090293 ! nitrogen catabolite regulation of transcription +created_by: tb +creation_date: 2010-02-24T02:31:53Z + +[Term] +id: GO:0090295 +name: nitrogen catabolite repression of transcription +namespace: biological_process +def: "A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources." [GOC:mah, GOC:rb, PMID:19104072] +synonym: "negative regulation of transcription by nitrogen catabolites" EXACT [GOC:mah] +synonym: "nitrogen catabolite repression" EXACT [GOC:mah, GOC:rb] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:0061984 ! catabolite repression +is_a: GO:0090293 ! nitrogen catabolite regulation of transcription +created_by: tb +creation_date: 2010-02-24T02:31:53Z + +[Term] +id: GO:0090296 +name: regulation of mitochondrial DNA replication +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." [GOC:tb] +synonym: "regulation of mitochondrial DNA synthesis" RELATED [GOC:tb] +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006264 ! mitochondrial DNA replication +relationship: regulates GO:0006264 ! mitochondrial DNA replication +created_by: tb +creation_date: 2010-03-12T03:58:25Z + +[Term] +id: GO:0090297 +name: positive regulation of mitochondrial DNA replication +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." [GOC:tb] +synonym: "positive regulation of mitochondrial DNA synthesis" RELATED [GOC:tb] +is_a: GO:0090296 ! regulation of mitochondrial DNA replication +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006264 ! mitochondrial DNA replication +relationship: positively_regulates GO:0006264 ! mitochondrial DNA replication +created_by: tb +creation_date: 2010-03-12T03:58:25Z + +[Term] +id: GO:0090298 +name: negative regulation of mitochondrial DNA replication +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." [GOC:tb] +synonym: "negative regulation of mitochondrial DNA synthesis" RELATED [GOC:tb] +is_a: GO:0090296 ! regulation of mitochondrial DNA replication +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006264 ! mitochondrial DNA replication +relationship: negatively_regulates GO:0006264 ! mitochondrial DNA replication +created_by: tb +creation_date: 2010-03-12T03:58:25Z + +[Term] +id: GO:0090299 +name: regulation of neural crest formation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] +is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014029 ! neural crest formation +relationship: regulates GO:0014029 ! neural crest formation +created_by: tb +creation_date: 2010-03-12T04:08:26Z + +[Term] +id: GO:0090300 +name: positive regulation of neural crest formation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] +is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0090299 ! regulation of neural crest formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014029 ! neural crest formation +relationship: positively_regulates GO:0014029 ! neural crest formation +created_by: tb +creation_date: 2010-03-12T04:08:26Z + +[Term] +id: GO:0090301 +name: negative regulation of neural crest formation +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] +is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0090299 ! regulation of neural crest formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014029 ! neural crest formation +relationship: negatively_regulates GO:0014029 ! neural crest formation +created_by: tb +creation_date: 2010-03-12T04:08:26Z + +[Term] +id: GO:0090303 +name: positive regulation of wound healing +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:BHF] +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:1903036 ! positive regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042060 ! wound healing +relationship: positively_regulates GO:0042060 ! wound healing +created_by: tb +creation_date: 2010-03-22T02:12:03Z + +[Term] +id: GO:0090304 +name: nucleic acid metabolic process +namespace: biological_process +def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0043170 ! macromolecule metabolic process +created_by: tb +creation_date: 2010-04-07T10:18:47Z + +[Term] +id: GO:0090305 +name: nucleic acid phosphodiester bond hydrolysis +namespace: biological_process +def: "The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis." [GOC:dph, GOC:tb] +synonym: "nucleic acid cleavage" EXACT [GOC:dph, GOC:tb] +is_a: GO:0090304 ! nucleic acid metabolic process +created_by: tb +creation_date: 2010-04-07T10:26:30Z + +[Term] +id: GO:0090306 +name: spindle assembly involved in meiosis +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis." [GOC:tb, GOC:vw] +synonym: "meiotic spindle assembly" EXACT [GOC:vw] +is_a: GO:0000212 ! meiotic spindle organization +is_a: GO:0051225 ! spindle assembly +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0140013 ! meiotic nuclear division +relationship: part_of GO:0140013 ! meiotic nuclear division +created_by: tb +creation_date: 2010-04-09T11:21:56Z + +[Term] +id: GO:0090307 +name: mitotic spindle assembly +namespace: biological_process +def: "Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied." [GOC:tb, GOC:vw] +synonym: "spindle assembly involved in mitosis" EXACT [] +is_a: GO:0007052 ! mitotic spindle organization +is_a: GO:0051225 ! spindle assembly +intersection_of: GO:0051225 ! spindle assembly +intersection_of: part_of GO:0140014 ! mitotic nuclear division +relationship: part_of GO:0140014 ! mitotic nuclear division +created_by: tb +creation_date: 2010-04-09T11:31:28Z + +[Term] +id: GO:0090308 +name: regulation of DNA methylation-dependent heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin." [GOC:BHF] +synonym: "regulation of methylation-dependent chromatin silencing" BROAD [] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +relationship: regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +created_by: tb +creation_date: 2010-04-09T02:12:53Z + +[Term] +id: GO:0090309 +name: positive regulation of DNA methylation-dependent heterochromatin assembly +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin." [GOC:BHF] +synonym: "positive regulation of methylation-dependent chromatin silencing" BROAD [] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:0090308 ! regulation of DNA methylation-dependent heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +relationship: positively_regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +created_by: tb +creation_date: 2010-04-09T02:12:53Z + +[Term] +id: GO:0090310 +name: negative regulation of DNA methylation-dependent heterochromatin assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin." [GOC:BHF] +synonym: "negative regulation of methylation-dependent chromatin silencing" BROAD [] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +is_a: GO:0090308 ! regulation of DNA methylation-dependent heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +relationship: negatively_regulates GO:0006346 ! DNA methylation-dependent heterochromatin assembly +created_by: tb +creation_date: 2010-04-09T02:12:53Z + +[Term] +id: GO:0090311 +name: regulation of protein deacetylation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:tb] +synonym: "regulation of protein amino acid deacetylation" EXACT [GOC:bf] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006476 ! protein deacetylation +relationship: regulates GO:0006476 ! protein deacetylation +created_by: tb +creation_date: 2010-04-14T01:30:45Z + +[Term] +id: GO:0090312 +name: positive regulation of protein deacetylation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ecd, PMID:20027304] +synonym: "positive regulation of protein amino acid deacetylation" EXACT [GOC:bf] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:0090311 ! regulation of protein deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006476 ! protein deacetylation +relationship: positively_regulates GO:0006476 ! protein deacetylation +created_by: tb +creation_date: 2010-04-14T01:30:45Z + +[Term] +id: GO:0090313 +name: regulation of protein targeting to membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein." [GOC:tb] +is_a: GO:1903533 ! regulation of protein targeting +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006612 ! protein targeting to membrane +relationship: regulates GO:0006612 ! protein targeting to membrane +created_by: tb +creation_date: 2010-04-16T03:42:22Z + +[Term] +id: GO:0090314 +name: positive regulation of protein targeting to membrane +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein." [GOC:tb] +is_a: GO:0090313 ! regulation of protein targeting to membrane +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006612 ! protein targeting to membrane +relationship: positively_regulates GO:0006612 ! protein targeting to membrane +created_by: tb +creation_date: 2010-04-16T03:42:22Z + +[Term] +id: GO:0090315 +name: negative regulation of protein targeting to membrane +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein." [GOC:tb] +is_a: GO:0090313 ! regulation of protein targeting to membrane +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006612 ! protein targeting to membrane +relationship: negatively_regulates GO:0006612 ! protein targeting to membrane +created_by: tb +creation_date: 2010-04-16T03:42:22Z + +[Term] +id: GO:0090316 +name: positive regulation of intracellular protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006886 ! intracellular protein transport +relationship: positively_regulates GO:0006886 ! intracellular protein transport +created_by: tb +creation_date: 2010-04-16T03:45:07Z + +[Term] +id: GO:0090317 +name: negative regulation of intracellular protein transport +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006886 ! intracellular protein transport +relationship: negatively_regulates GO:0006886 ! intracellular protein transport +created_by: tb +creation_date: 2010-04-16T03:45:07Z + +[Term] +id: GO:0090318 +name: regulation of chylomicron remodeling +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:tb] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034371 ! chylomicron remodeling +relationship: regulates GO:0034371 ! chylomicron remodeling +created_by: tb +creation_date: 2010-04-30T10:09:08Z + +[Term] +id: GO:0090319 +name: positive regulation of chylomicron remodeling +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid." [GOC:BHF] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0090318 ! regulation of chylomicron remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034371 ! chylomicron remodeling +relationship: positively_regulates GO:0034371 ! chylomicron remodeling +created_by: tb +creation_date: 2010-04-30T10:09:08Z + +[Term] +id: GO:0090320 +name: regulation of chylomicron remnant clearance +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded." [GOC:tb] +is_a: GO:0010984 ! regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034382 ! chylomicron remnant clearance +relationship: regulates GO:0034382 ! chylomicron remnant clearance +created_by: tb +creation_date: 2010-04-30T10:20:26Z + +[Term] +id: GO:0090321 +name: positive regulation of chylomicron remnant clearance +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded." [GOC:BHF] +is_a: GO:0010986 ! positive regulation of lipoprotein particle clearance +is_a: GO:0090320 ! regulation of chylomicron remnant clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034382 ! chylomicron remnant clearance +relationship: positively_regulates GO:0034382 ! chylomicron remnant clearance +created_by: tb +creation_date: 2010-04-30T10:20:26Z + +[Term] +id: GO:0090322 +name: regulation of superoxide metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species." [GOC:tb] +synonym: "regulation of superoxide metabolism" EXACT [GOC:tb] +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006801 ! superoxide metabolic process +relationship: regulates GO:0006801 ! superoxide metabolic process +created_by: tb +creation_date: 2010-05-06T02:29:05Z + +[Term] +id: GO:0090323 +name: prostaglandin secretion involved in immune response +namespace: biological_process +def: "The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring." [GOC:dph, GOC:tb] +is_a: GO:0002440 ! production of molecular mediator of immune response +is_a: GO:0032310 ! prostaglandin secretion +intersection_of: GO:0032310 ! prostaglandin secretion +intersection_of: part_of GO:0006955 ! immune response +relationship: part_of GO:0006955 ! immune response +created_by: tb +creation_date: 2010-05-12T10:41:04Z + +[Term] +id: GO:0090324 +name: negative regulation of oxidative phosphorylation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis." [GOC:BHF] +is_a: GO:0002082 ! regulation of oxidative phosphorylation +is_a: GO:0042326 ! negative regulation of phosphorylation +is_a: GO:1903579 ! negative regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006119 ! oxidative phosphorylation +relationship: negatively_regulates GO:0006119 ! oxidative phosphorylation +created_by: tb +creation_date: 2010-05-14T10:21:33Z + +[Term] +id: GO:0090325 +name: regulation of locomotion involved in locomotory behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0040012 ! regulation of locomotion +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031987 ! locomotion involved in locomotory behavior +relationship: regulates GO:0031987 ! locomotion involved in locomotory behavior +created_by: tb +creation_date: 2010-05-14T10:24:29Z + +[Term] +id: GO:0090326 +name: positive regulation of locomotion involved in locomotory behavior +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0040017 ! positive regulation of locomotion +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior +relationship: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior +created_by: tb +creation_date: 2010-05-14T10:26:58Z + +[Term] +id: GO:0090327 +name: negative regulation of locomotion involved in locomotory behavior +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] +is_a: GO:0040013 ! negative regulation of locomotion +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior +relationship: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior +created_by: tb +creation_date: 2010-05-14T10:26:58Z + +[Term] +id: GO:0090328 +name: regulation of olfactory learning +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue." [GOC:dph, GOC:tb] +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008355 ! olfactory learning +relationship: regulates GO:0008355 ! olfactory learning +created_by: tb +creation_date: 2010-05-14T10:37:22Z + +[Term] +id: GO:0090329 +name: regulation of DNA-dependent DNA replication +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." [GOC:dph, GOC:tb] +is_a: GO:0006275 ! regulation of DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006261 ! DNA-dependent DNA replication +relationship: regulates GO:0006261 ! DNA-dependent DNA replication +created_by: tb +creation_date: 2010-05-14T10:42:04Z + +[Term] +id: GO:0090330 +name: regulation of platelet aggregation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:dph, GOC:tb] +is_a: GO:0010543 ! regulation of platelet activation +is_a: GO:0034110 ! regulation of homotypic cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070527 ! platelet aggregation +relationship: regulates GO:0070527 ! platelet aggregation +created_by: tb +creation_date: 2010-05-14T10:46:08Z + +[Term] +id: GO:0090331 +name: negative regulation of platelet aggregation +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:BHF] +synonym: "platelet disaggregation" NARROW [GOC:dph, PMID:12871378] +is_a: GO:0010544 ! negative regulation of platelet activation +is_a: GO:0034111 ! negative regulation of homotypic cell-cell adhesion +is_a: GO:0090330 ! regulation of platelet aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070527 ! platelet aggregation +relationship: negatively_regulates GO:0070527 ! platelet aggregation +created_by: tb +creation_date: 2010-05-14T10:46:08Z + +[Term] +id: GO:0090332 +name: stomatal closure +namespace: biological_process +def: "The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange." [GOC:tb] +is_a: GO:0010118 ! stomatal movement +created_by: tb +creation_date: 2010-05-26T02:14:49Z + +[Term] +id: GO:0090333 +name: regulation of stomatal closure +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange." [GOC:tb] +is_a: GO:0010119 ! regulation of stomatal movement +relationship: regulates GO:0090332 ! stomatal closure +created_by: tb +creation_date: 2010-05-26T02:14:49Z + +[Term] +id: GO:0090334 +name: regulation of cell wall (1->3)-beta-D-glucan biosynthetic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells." [GOC:tb] +synonym: "regulation of cell wall 1,3-beta-D-glucan biosynthetic process" BROAD [] +synonym: "regulation of cell wall 1,3-beta-glucan biosynthetic process" BROAD [] +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0032953 ! regulation of (1->3)-beta-D-glucan biosynthetic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034411 ! cell wall (1->3)-beta-D-glucan biosynthetic process +relationship: regulates GO:0034411 ! cell wall (1->3)-beta-D-glucan biosynthetic process +created_by: tb +creation_date: 2010-06-01T03:11:34Z + +[Term] +id: GO:0090335 +name: regulation of brown fat cell differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria." [GOC:tb] +is_a: GO:0045598 ! regulation of fat cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050873 ! brown fat cell differentiation +relationship: regulates GO:0050873 ! brown fat cell differentiation +created_by: tb +creation_date: 2010-06-01T03:16:57Z + +[Term] +id: GO:0090336 +name: positive regulation of brown fat cell differentiation +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria." [GOC:BHF] +is_a: GO:0045600 ! positive regulation of fat cell differentiation +is_a: GO:0090335 ! regulation of brown fat cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050873 ! brown fat cell differentiation +relationship: positively_regulates GO:0050873 ! brown fat cell differentiation +created_by: tb +creation_date: 2010-06-01T03:19:26Z + +[Term] +id: GO:0090337 +name: regulation of formin-nucleated actin cable assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins." [GOC:jh, GOC:tb, PMID:12810699, PMID:15923184] +is_a: GO:0032231 ! regulation of actin filament bundle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070649 ! formin-nucleated actin cable assembly +relationship: regulates GO:0070649 ! formin-nucleated actin cable assembly +created_by: tb +creation_date: 2010-06-01T03:26:31Z + +[Term] +id: GO:0090338 +name: positive regulation of formin-nucleated actin cable assembly +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins." [GOC:jh, GOC:tb, PMID:12810699, PMID:15923184] +is_a: GO:0032233 ! positive regulation of actin filament bundle assembly +is_a: GO:0090337 ! regulation of formin-nucleated actin cable assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070649 ! formin-nucleated actin cable assembly +relationship: positively_regulates GO:0070649 ! formin-nucleated actin cable assembly +created_by: tb +creation_date: 2010-06-01T03:26:31Z + +[Term] +id: GO:0090339 +name: negative regulation of formin-nucleated actin cable assembly +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins." [GOC:jh, GOC:tb, PMID:12810699, PMID:15923184] +is_a: GO:0032232 ! negative regulation of actin filament bundle assembly +is_a: GO:0090337 ! regulation of formin-nucleated actin cable assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070649 ! formin-nucleated actin cable assembly +relationship: negatively_regulates GO:0070649 ! formin-nucleated actin cable assembly +created_by: tb +creation_date: 2010-06-01T03:26:31Z + +[Term] +id: GO:0090340 +name: positive regulation of secretion of lysosomal enzymes +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell." [GOC:BHF] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0090182 ! regulation of secretion of lysosomal enzymes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033299 ! secretion of lysosomal enzymes +relationship: positively_regulates GO:0033299 ! secretion of lysosomal enzymes +created_by: tb +creation_date: 2010-06-01T03:35:57Z + +[Term] +id: GO:0090341 +name: negative regulation of secretion of lysosomal enzymes +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell." [GOC:BHF] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0090182 ! regulation of secretion of lysosomal enzymes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033299 ! secretion of lysosomal enzymes +relationship: negatively_regulates GO:0033299 ! secretion of lysosomal enzymes +created_by: tb +creation_date: 2010-06-01T03:35:57Z + +[Term] +id: GO:0090342 +name: regulation of cell aging +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007569 ! cell aging +relationship: regulates GO:0007569 ! cell aging +created_by: tb +creation_date: 2010-06-02T10:12:37Z + +[Term] +id: GO:0090343 +name: positive regulation of cell aging +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0090342 ! regulation of cell aging +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007569 ! cell aging +relationship: positively_regulates GO:0007569 ! cell aging +created_by: tb +creation_date: 2010-06-02T10:12:37Z + +[Term] +id: GO:0090344 +name: negative regulation of cell aging +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan." [GOC:BHF, GOC:dph, GOC:tb] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0090342 ! regulation of cell aging +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007569 ! cell aging +relationship: negatively_regulates GO:0007569 ! cell aging +created_by: tb +creation_date: 2010-06-02T10:12:37Z + +[Term] +id: GO:0090345 +name: cellular organohalogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0044237 ! cellular metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090346 +name: cellular organofluorine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0090345 ! cellular organohalogen metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090347 +name: regulation of cellular organohalogen metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090345 ! cellular organohalogen metabolic process +relationship: regulates GO:0090345 ! cellular organohalogen metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090348 +name: regulation of cellular organofluorine metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0090347 ! regulation of cellular organohalogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090346 ! cellular organofluorine metabolic process +relationship: regulates GO:0090346 ! cellular organofluorine metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090349 +name: negative regulation of cellular organohalogen metabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0090347 ! regulation of cellular organohalogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090345 ! cellular organohalogen metabolic process +relationship: negatively_regulates GO:0090345 ! cellular organohalogen metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090350 +name: negative regulation of cellular organofluorine metabolic process +namespace: biological_process +def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells." [GOC:BHF] +is_a: GO:0090348 ! regulation of cellular organofluorine metabolic process +is_a: GO:0090349 ! negative regulation of cellular organohalogen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090346 ! cellular organofluorine metabolic process +relationship: negatively_regulates GO:0090346 ! cellular organofluorine metabolic process +created_by: tb +creation_date: 2010-06-02T10:36:42Z + +[Term] +id: GO:0090351 +name: seedling development +namespace: biological_process +def: "The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge." [GOC:tb, PO:0007131] +xref: PO:0008037 +is_a: GO:0009791 ! post-embryonic development +created_by: tb +creation_date: 2010-06-10T03:33:10Z + +[Term] +id: GO:0090352 +name: regulation of nitrate assimilation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances." [GOC:tb] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1903314 ! regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042128 ! nitrate assimilation +relationship: regulates GO:0042128 ! nitrate assimilation +created_by: tb +creation_date: 2010-06-10T04:11:13Z + +[Term] +id: GO:0090353 +name: polygalacturonase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a polygalacturonase. Polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans." [GOC:tb] +is_a: GO:0004857 ! enzyme inhibitor activity +created_by: tb +creation_date: 2010-06-15T04:19:49Z + +[Term] +id: GO:0090354 +name: regulation of auxin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth." [GOC:tb] +synonym: "regulation of auxin metabolism" EXACT [GOC:tb] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009850 ! auxin metabolic process +relationship: regulates GO:0009850 ! auxin metabolic process +created_by: tb +creation_date: 2010-06-29T01:51:18Z + +[Term] +id: GO:0090355 +name: positive regulation of auxin metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth." [GOC:tb] +synonym: "positive regulation of auxin metabolism" EXACT [GOC:tb] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0090354 ! regulation of auxin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009850 ! auxin metabolic process +relationship: positively_regulates GO:0009850 ! auxin metabolic process +created_by: tb +creation_date: 2010-06-29T01:51:18Z + +[Term] +id: GO:0090356 +name: negative regulation of auxin metabolic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth." [GOC:tb] +synonym: "negative regulation of auxin metabolism" EXACT [GOC:tb] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0090354 ! regulation of auxin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009850 ! auxin metabolic process +relationship: negatively_regulates GO:0009850 ! auxin metabolic process +created_by: tb +creation_date: 2010-06-29T01:51:18Z + +[Term] +id: GO:0090357 +name: regulation of tryptophan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:tb] +synonym: "regulation of tryptophan metabolism" EXACT [GOC:tb] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006568 ! tryptophan metabolic process +relationship: regulates GO:0006568 ! tryptophan metabolic process +created_by: tb +creation_date: 2010-06-29T02:38:48Z + +[Term] +id: GO:0090358 +name: positive regulation of tryptophan metabolic process +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:tb] +synonym: "positive regulation of tryptophan metabolism" EXACT [GOC:tb] +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:0090357 ! regulation of tryptophan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006568 ! tryptophan metabolic process +relationship: positively_regulates GO:0006568 ! tryptophan metabolic process +created_by: tb +creation_date: 2010-06-29T02:38:48Z + +[Term] +id: GO:0090359 +name: negative regulation of abscisic acid biosynthetic process +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid." [GOC:tb] +synonym: "negative regulation of abscisic acid biosynthesis" EXACT [GOC:tb] +is_a: GO:0010115 ! regulation of abscisic acid biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009688 ! abscisic acid biosynthetic process +relationship: negatively_regulates GO:0009688 ! abscisic acid biosynthetic process +created_by: tb +creation_date: 2010-06-29T02:47:12Z + +[Term] +id: GO:0090360 +name: platelet-derived growth factor production +namespace: biological_process +def: "The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001816 ! cytokine production +created_by: tb +creation_date: 2010-07-12T10:32:27Z + +[Term] +id: GO:0090361 +name: regulation of platelet-derived growth factor production +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090360 ! platelet-derived growth factor production +relationship: regulates GO:0090360 ! platelet-derived growth factor production +created_by: tb +creation_date: 2010-07-12T10:32:27Z + +[Term] +id: GO:0090362 +name: positive regulation of platelet-derived growth factor production +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:BHF] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0090361 ! regulation of platelet-derived growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090360 ! platelet-derived growth factor production +relationship: positively_regulates GO:0090360 ! platelet-derived growth factor production +created_by: tb +creation_date: 2010-07-12T10:32:27Z + +[Term] +id: GO:0090363 +name: regulation of proteasome core complex assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles." [GOC:dph, GOC:elh, GOC:tb] +is_a: GO:0090364 ! regulation of proteasome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080129 ! proteasome core complex assembly +relationship: regulates GO:0080129 ! proteasome core complex assembly +created_by: tb +creation_date: 2010-07-12T10:48:57Z + +[Term] +id: GO:0090364 +name: regulation of proteasome assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex." [GOC:dph, GOC:elh, GOC:tb] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043248 ! proteasome assembly +relationship: regulates GO:0043248 ! proteasome assembly +created_by: tb +creation_date: 2010-07-12T10:55:21Z + +[Term] +id: GO:0090365 +name: regulation of mRNA modification +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:dph, GOC:sl, GOC:tb, PMID:14559896] +synonym: "regulation of mRNA editing" NARROW [] +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016556 ! mRNA modification +relationship: regulates GO:0016556 ! mRNA modification +created_by: tb +creation_date: 2010-07-12T11:04:45Z + +[Term] +id: GO:0090366 +name: positive regulation of mRNA modification +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0090365 ! regulation of mRNA modification +is_a: GO:1903313 ! positive regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016556 ! mRNA modification +relationship: positively_regulates GO:0016556 ! mRNA modification +created_by: tb +creation_date: 2010-07-12T11:04:45Z + +[Term] +id: GO:0090367 +name: negative regulation of mRNA modification +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:dph, GOC:sl, GOC:tb] +is_a: GO:0090365 ! regulation of mRNA modification +is_a: GO:1903312 ! negative regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016556 ! mRNA modification +relationship: negatively_regulates GO:0016556 ! mRNA modification +created_by: tb +creation_date: 2010-07-12T11:04:45Z + +[Term] +id: GO:0090368 +name: regulation of ornithine metabolic process +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006591 ! ornithine metabolic process +relationship: regulates GO:0006591 ! ornithine metabolic process +created_by: tb +creation_date: 2010-07-12T11:14:12Z + +[Term] +id: GO:0090369 +name: ornithine carbamoyltransferase inhibitor activity +namespace: molecular_function +def: "Stops, prevents, or reduces ornithine carbamoyltransferase activity, the catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline." [GOC:dph, GOC:jp, GOC:tb] +is_a: GO:0004857 ! enzyme inhibitor activity +relationship: negatively_regulates GO:0004585 ! ornithine carbamoyltransferase activity +relationship: part_of GO:0090368 ! regulation of ornithine metabolic process +created_by: tb +creation_date: 2010-07-12T11:19:55Z + +[Term] +id: GO:0090370 +name: negative regulation of cholesterol efflux +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle." [GOC:dph, GOC:tb, GOC:yaf] +is_a: GO:0010874 ! regulation of cholesterol efflux +is_a: GO:0032375 ! negative regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033344 ! cholesterol efflux +relationship: negatively_regulates GO:0033344 ! cholesterol efflux +created_by: tb +creation_date: 2010-07-12T11:26:04Z + +[Term] +id: GO:0090371 +name: regulation of glycerol transport +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:jh, GOC:tb] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015793 ! glycerol transport +relationship: regulates GO:0015793 ! glycerol transport +created_by: tb +creation_date: 2010-07-12T11:30:22Z + +[Term] +id: GO:0090372 +name: positive regulation of glycerol transport +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:jh, GOC:tb] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0090371 ! regulation of glycerol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015793 ! glycerol transport +relationship: positively_regulates GO:0015793 ! glycerol transport +created_by: tb +creation_date: 2010-07-12T11:30:22Z + +[Term] +id: GO:0090373 +name: negative regulation of glycerol transport +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:jh, GOC:tb] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0090371 ! regulation of glycerol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015793 ! glycerol transport +relationship: negatively_regulates GO:0015793 ! glycerol transport +created_by: tb +creation_date: 2010-07-12T11:30:22Z + +[Term] +id: GO:0090374 +name: oligopeptide export from mitochondrion +namespace: biological_process +def: "The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [PMID:11251115] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: tb +creation_date: 2010-08-27T04:38:18Z + +[Term] +id: GO:0090375 +name: negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions." [GOC:tb] +synonym: "negative regulation of transcription from RNA polymerase II promoter in response to iron deficiency" EXACT [GOC:tb] +is_a: GO:0033217 ! regulation of transcription from RNA polymerase II promoter in response to iron ion starvation +is_a: GO:0097201 ! negative regulation of transcription from RNA polymerase II promoter in response to stress +created_by: tb +creation_date: 2010-09-01T01:22:23Z + +[Term] +id: GO:0090376 +name: seed trichome differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function." [GOC:tb, PMID:17905721] +synonym: "cotton fiber development" NARROW [GOC:tb] +synonym: "seed hair differentiation" EXACT [PO:0004511] +synonym: "seed trichome development" RELATED [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0010026 ! trichome differentiation +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0048316 ! seed development +created_by: tb +creation_date: 2010-09-15T02:07:10Z + +[Term] +id: GO:0090377 +name: seed trichome initiation +namespace: biological_process +def: "The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis." [PMID:17905721] +comment: These processes continue up to 3 days post-anthesis (DPA) in Gossypium spp. +synonym: "seed trichome fate commitment" EXACT [GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0045165 ! cell fate commitment +relationship: part_of GO:0090376 ! seed trichome differentiation +created_by: tb +creation_date: 2010-09-15T02:13:59Z + +[Term] +id: GO:0090378 +name: seed trichome elongation +namespace: biological_process +def: "The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell." [GOC:tb] +comment: The increase in length of the seed trichome without cell division. Elongation is defined to be from 5 to 20 DPA in Gossypium spp. +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009826 ! unidimensional cell growth +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0090376 ! seed trichome differentiation +created_by: tb +creation_date: 2010-09-15T02:20:47Z + +[Term] +id: GO:0090379 +name: secondary cell wall biogenesis involved in seed trichome differentiation +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete." [GOC:tb] +comment: The processes involved in the massive amount of secondary wall cellulose synthesis in seed trichomes continue to 30 DPA in Gossypium spp. +synonym: "secondary cell wall biosynthesis involved in seed trichome differentiation" EXACT [GOC:tb] +synonym: "seed trichome secondary wall biosynthesis" RELATED [GOC:tb] +is_a: GO:0009834 ! plant-type secondary cell wall biogenesis +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +intersection_of: GO:0009834 ! plant-type secondary cell wall biogenesis +intersection_of: part_of GO:0090376 ! seed trichome differentiation +relationship: part_of GO:0090376 ! seed trichome differentiation +created_by: tb +creation_date: 2010-09-15T02:24:34Z + +[Term] +id: GO:0090380 +name: seed trichome maturation +namespace: biological_process +def: "A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state." [GOC:tb] +comment: These processes continue to 60 DPA in Gossypium spp. +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0048469 ! cell maturation +relationship: part_of GO:0090376 ! seed trichome differentiation +created_by: tb +creation_date: 2010-09-15T02:29:42Z + +[Term] +id: GO:0090381 +name: regulation of heart induction +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart." [GOC:dph, GOC:tb] +is_a: GO:0003156 ! regulation of animal organ formation +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003129 ! heart induction +relationship: regulates GO:0003129 ! heart induction +created_by: tb +creation_date: 2010-10-04T10:23:43Z + +[Term] +id: GO:0090382 +name: phagosome maturation +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome." [GOC:kmv, GOC:tb] +is_a: GO:0006996 ! organelle organization +created_by: tb +creation_date: 2010-10-19T11:10:34Z + +[Term] +id: GO:0090383 +name: phagosome acidification +namespace: biological_process +def: "Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion." [GOC:kmv, GOC:tb] +synonym: "phagosomal acidification" EXACT [GOC:kmv, GOC:tb] +is_a: GO:0051452 ! intracellular pH reduction +relationship: part_of GO:0090382 ! phagosome maturation +created_by: tb +creation_date: 2010-10-27T10:20:22Z + +[Term] +id: GO:0090384 +name: phagosome-lysosome docking +namespace: biological_process +def: "The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:kmv, GOC:tb] +synonym: "lysosome recruitment to phagosome" EXACT [GOC:kmv, GOC:tb] +is_a: GO:0048278 ! vesicle docking +relationship: part_of GO:0001845 ! phagolysosome assembly +created_by: tb +creation_date: 2010-10-27T10:24:28Z + +[Term] +id: GO:0090385 +name: phagosome-lysosome fusion +namespace: biological_process +def: "The creation of a phagolysosome from a phagosome and a lysosome." [GOC:kmv, GOC:tb] +is_a: GO:0006906 ! vesicle fusion +relationship: part_of GO:0001845 ! phagolysosome assembly +created_by: tb +creation_date: 2010-10-27T10:24:28Z + +[Term] +id: GO:0090386 +name: phagosome maturation involved in apoptotic cell clearance +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome." [GOC:kmv, GOC:tb] +is_a: GO:0090382 ! phagosome maturation +intersection_of: GO:0090382 ! phagosome maturation +intersection_of: part_of GO:0043277 ! apoptotic cell clearance +relationship: part_of GO:0043277 ! apoptotic cell clearance +created_by: tb +creation_date: 2010-10-27T10:57:39Z + +[Term] +id: GO:0090387 +name: phagolysosome assembly involved in apoptotic cell clearance +namespace: biological_process +def: "The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance." [GOC:kmv, GOC:tb] +is_a: GO:0001845 ! phagolysosome assembly +intersection_of: GO:0001845 ! phagolysosome assembly +intersection_of: part_of GO:0043277 ! apoptotic cell clearance +relationship: part_of GO:0090386 ! phagosome maturation involved in apoptotic cell clearance +created_by: tb +creation_date: 2010-10-27T10:57:39Z + +[Term] +id: GO:0090388 +name: phagosome-lysosome docking involved in apoptotic cell clearance +namespace: biological_process +def: "The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere." [GOC:kmv, GOC:tb] +is_a: GO:0090384 ! phagosome-lysosome docking +intersection_of: GO:0090384 ! phagosome-lysosome docking +intersection_of: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance +relationship: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance +created_by: tb +creation_date: 2010-10-27T10:57:39Z + +[Term] +id: GO:0090389 +name: phagosome-lysosome fusion involved in apoptotic cell clearance +namespace: biological_process +def: "The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance." [GOC:kmv, GOC:tb] +is_a: GO:0090385 ! phagosome-lysosome fusion +intersection_of: GO:0090385 ! phagosome-lysosome fusion +intersection_of: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance +relationship: part_of GO:0090387 ! phagolysosome assembly involved in apoptotic cell clearance +created_by: tb +creation_date: 2010-10-27T10:57:39Z + +[Term] +id: GO:0090390 +name: phagosome acidification involved in apoptotic cell clearance +namespace: biological_process +def: "Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance." [GOC:kmv, GOC:tb] +is_a: GO:0090383 ! phagosome acidification +intersection_of: GO:0090383 ! phagosome acidification +intersection_of: part_of GO:0090386 ! phagosome maturation involved in apoptotic cell clearance +relationship: part_of GO:0090386 ! phagosome maturation involved in apoptotic cell clearance +created_by: tb +creation_date: 2010-10-27T10:57:39Z + +[Term] +id: GO:0090391 +name: granum assembly +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts." [GOC:tb] +synonym: "grana formation" EXACT [GOC:tb] +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0009658 ! chloroplast organization +created_by: tb +creation_date: 2010-12-08T04:25:46Z + +[Term] +id: GO:0090392 +name: sepal giant cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C." [GOC:tb, PMID:20485493] +is_a: GO:0090627 ! plant epidermal cell differentiation +created_by: tb +creation_date: 2010-12-14T04:38:06Z + +[Term] +id: GO:0090393 +name: sepal giant cell development +namespace: biological_process +def: "The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:tb] +synonym: "sepal giant cell formation" RELATED [GOC:tb] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0090392 ! sepal giant cell differentiation +created_by: tb +creation_date: 2010-12-14T04:44:34Z + +[Term] +id: GO:0090394 +name: negative regulation of excitatory postsynaptic potential +namespace: biological_process +def: "Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:BHF] +synonym: "negative regulation of EPSP" RELATED [] +synonym: "negative regulation of excitatory post-synaptic membrane potential" EXACT [] +synonym: "reduction of excitatory postsynaptic membrane potential" EXACT [GOC:bf] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0050805 ! negative regulation of synaptic transmission +is_a: GO:0098815 ! modulation of excitatory postsynaptic potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: negatively_regulates GO:0060079 ! excitatory postsynaptic potential +relationship: negatively_regulates GO:0060079 ! excitatory postsynaptic potential +created_by: tb +creation_date: 2010-12-15T01:43:12Z + +[Term] +id: GO:0090395 +name: plant cell papilla +namespace: cellular_component +def: "A cell projection that is a short, rounded projection from a plant epidermal cell." [GOC:tb] +comment: Part of papilla cell (PO:0025166), which is a shoot epidermal cell (PO:0025165) in plants. Replaces the obsolete term papillae (PO:0002001). +is_a: GO:0042995 ! cell projection +created_by: tb +creation_date: 2010-12-15T03:26:20Z + +[Term] +id: GO:0090396 +name: leaf papilla +namespace: cellular_component +def: "A plant cell papilla that is part of a leaf papilla cell." [GOC:tb] +comment: Part of leaf papilla cell (PO:0025167). +is_a: GO:0090395 ! plant cell papilla +created_by: tb +creation_date: 2010-12-15T03:26:20Z + +[Term] +id: GO:0090397 +name: stigma papilla +namespace: cellular_component +def: "A plant cell papilla that is part of a stigma papilla cell." [GOC:tb] +comment: Part of stigma papilla cell (PO:0025168). +is_a: GO:0090395 ! plant cell papilla +created_by: tb +creation_date: 2010-12-15T03:26:20Z + +[Term] +id: GO:0090398 +name: cellular senescence +namespace: biological_process +def: "A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest." [GOC:BHF] +is_a: GO:0007569 ! cell aging +is_a: GO:0033554 ! cellular response to stress +created_by: tb +creation_date: 2011-01-05T02:27:08Z + +[Term] +id: GO:0090399 +name: replicative senescence +namespace: biological_process +def: "A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging." [GOC:BHF] +is_a: GO:0007569 ! cell aging +created_by: tb +creation_date: 2011-01-05T02:32:29Z + +[Term] +id: GO:0090400 +name: stress-induced premature senescence +namespace: biological_process +def: "A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays." [GOC:BHF] +synonym: "SIPS" EXACT [GOC:BHF] +is_a: GO:0090398 ! cellular senescence +created_by: tb +creation_date: 2011-01-05T02:32:29Z + +[Term] +id: GO:0090401 +name: obsolete viral-induced premature senescence +namespace: biological_process +def: "OBSOLETE. A cellular senescence process associated with the dismantling of a cell as a response to viral infection." [GOC:BHF] +comment: The reason for obsoletion is was not clearly defined. There is nothing in the literature that mentions this process; there are papers that mention viral proteins overcoming premature senescence, for example, PMID:22326283. +is_obsolete: true +created_by: tb +creation_date: 2011-01-05T02:37:57Z + +[Term] +id: GO:0090402 +name: oncogene-induced cell senescence +namespace: biological_process +def: "A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family." [GOC:BHF] +synonym: "OIS" EXACT [GOC:BHF] +is_a: GO:0090398 ! cellular senescence +created_by: tb +creation_date: 2011-01-05T02:37:57Z + +[Term] +id: GO:0090403 +name: oxidative stress-induced premature senescence +namespace: biological_process +def: "A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals." [GOC:BHF] +is_a: GO:0090400 ! stress-induced premature senescence +relationship: part_of GO:0034599 ! cellular response to oxidative stress +created_by: tb +creation_date: 2011-01-05T02:37:57Z + +[Term] +id: GO:0090404 +name: pollen tube tip +namespace: cellular_component +def: "The region at growing end of the pollen tube cell, where polarized growth occurs." [GOC:tb, PO:0025195, PO:0025281] +is_a: GO:0035838 ! growing cell tip +relationship: part_of GO:0090406 ! pollen tube +created_by: tb +creation_date: 2011-01-10T10:25:58Z + +[Term] +id: GO:0090405 +name: unicellular trichome branch +namespace: cellular_component +def: "A cell projection part that is a branch of a unicellular trichome." [GOC:tb, PO:0025537] +comment: Unicellular trichome (PO:0025537) is a trichome(PO:0000282) that is a single plant cell (PO:0009002). For a cell that forms a branch of a multicellular trichome, see multicellular trichome branch cell (PO:0025163). +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0090552 ! unicellular trichome apex +relationship: part_of GO:0042995 ! cell projection +created_by: tb +creation_date: 2011-01-10T10:30:39Z + +[Term] +id: GO:0090406 +name: pollen tube +namespace: cellular_component +def: "A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain." [GOC:tb, PO:0025195, PO:0025281] +comment: Carries the male gametes to into or near the ovule. May be branched in gymnosperms. This term replaces the obsolete term PO:0006345. Part of pollen tube cell (PO:0025195). +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: tb +creation_date: 2011-01-10T01:59:40Z + +[Term] +id: GO:0090407 +name: organophosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose." [GOC:chem_mtg] +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: tb +creation_date: 2011-02-26T02:22:41Z + +[Term] +id: GO:0090408 +name: phloem nitrate loading +namespace: biological_process +def: "The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink." [GOC:tb] +is_a: GO:0015706 ! nitrate transport +is_a: GO:0110126 ! phloem loading +created_by: tb +creation_date: 2011-06-01T10:06:21Z + +[Term] +id: GO:0090409 +name: malonyl-CoA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate." [MetaCyc:RXN-12359] +xref: EC:6.2.1.n3 +xref: MetaCyc:RXN-12359 +xref: RHEA:32139 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity +created_by: tb +creation_date: 2011-06-10T01:51:16Z + +[Term] +id: GO:0090410 +name: malonate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion." [GOC:tb] +is_a: GO:0043649 ! dicarboxylic acid catabolic process +created_by: tb +creation_date: 2011-06-10T01:53:43Z + +[Term] +id: GO:0090411 +name: brassinosteroid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a brassinosteroid." [GOC:tb] +is_a: GO:0005496 ! steroid binding +created_by: tb +creation_date: 2011-08-11T02:25:30Z + +[Term] +id: GO:0090412 +name: obsolete positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process." [GOC:vw] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2011-09-01T03:10:41Z + +[Term] +id: GO:0090413 +name: obsolete negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process." [GOC:vw] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process" EXACT [] +is_obsolete: true +created_by: tb +creation_date: 2011-09-01T03:10:41Z + +[Term] +id: GO:0090414 +name: molybdate ion export from vacuole +namespace: biological_process +def: "The directed movement of molybdate ions out of the vacuole." [GOC:tb] +is_a: GO:0015689 ! molybdate ion transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: tb +creation_date: 2011-09-15T02:08:43Z + +[Term] +id: GO:0090415 +name: 7-hydroxymethyl chlorophyll a reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O." [GOC:kad, PMID:21934147] +is_a: GO:0052592 ! oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor +created_by: tb +creation_date: 2011-10-03T12:08:27Z + +[Term] +id: GO:0090416 +name: nicotinate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of nicotinate from one side of a membrane to the other." [GOC:tb] +xref: Reactome:R-HSA-8869603 "SLC22A13 transports NCA from extracellular region to cytosol" +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:2001142 ! nicotinate transport +created_by: tb +creation_date: 2011-10-19T11:09:59Z + +[Term] +id: GO:0090417 +name: N-methylnicotinate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of N-methylnicotinate from one side of a membrane to the other." [GOC:tb] +synonym: "N-methylnicotinate transporter activity" RELATED [] +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +relationship: part_of GO:2001143 ! N-methylnicotinate transport +created_by: tb +creation_date: 2011-10-19T11:09:59Z + +[Term] +id: GO:0090418 +name: obsolete positive regulation of transcription involved in S-phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the S phase of the mitotic cell cycle." [PMID:16912276] +comment: This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'. +synonym: "activation of S phase specific transcription in the mitotic cell cycle" RELATED [] +synonym: "activation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle" RELATED [] +synonym: "activation of transcription involved in S phase of mitotic cell cycle" RELATED [] +synonym: "positive regulation of S phase specific transcription in the mitotic cell cycle" RELATED [] +synonym: "positive regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle" RELATED [] +synonym: "positive regulation of transcription involved in S-phase of mitotic cell cycle" EXACT [] +synonym: "up-regulation of S phase specific transcription in the mitotic cell cycle" RELATED [] +synonym: "up-regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle" RELATED [] +synonym: "up-regulation of transcription involved in S phase of mitotic cell cycle" RELATED [] +is_obsolete: true +created_by: tb +creation_date: 2011-10-26T03:54:00Z + +[Term] +id: GO:0090419 +name: negative regulation of transcription involved in G2/M transition of mitotic cell cycle +namespace: biological_process +def: "Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle." [GOC:mtg_cell_cycle, PMID:10747051] +synonym: "down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle" RELATED [] +synonym: "negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle" RELATED [] +is_a: GO:0000117 ! regulation of transcription involved in G2/M transition of mitotic cell cycle +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: part_of GO:0000086 ! G2/M transition of mitotic cell cycle +created_by: tb +creation_date: 2011-10-26T03:59:41Z + +[Term] +id: GO:0090420 +name: naphthalene-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving naphthalene-containing compounds." [GOC:dph, GOC:tb] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: tb +creation_date: 2011-12-12T11:32:34Z + +[Term] +id: GO:0090421 +name: embryonic meristem initiation +namespace: biological_process +def: "Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation." [GOC:tb] +is_a: GO:0010014 ! meristem initiation +created_by: tb +creation_date: 2012-04-13T02:52:34Z + +[Term] +id: GO:0090422 +name: thiamine pyrophosphate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other." [GOC:tb] +synonym: "thiamine diphosphate transporter activity" EXACT [GOC:tb] +synonym: "thiamine pyrophosphate transporter activity" NARROW [] +xref: Reactome:R-HSA-8875838 "SLC25A19 transports ThDP from cytosol to mitochondrial matrix" +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015605 ! organophosphate ester transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:0030974 ! thiamine pyrophosphate transmembrane transport +created_by: tb +creation_date: 2012-04-17T12:28:11Z + +[Term] +id: GO:0090423 +name: phytochelatin-metal complex formation +namespace: biological_process +def: "A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex." [GOC:tb] +synonym: "low molecular weight phytochelatin complex formation" RELATED [] +synonym: "LWM phytochelatin complex formation" RELATED [] +is_a: GO:0046937 ! phytochelatin metabolic process +created_by: tb +creation_date: 2012-04-20T03:46:45Z + +[Term] +id: GO:0090424 +name: phytochelatin-metal-sulfur complex formation +namespace: biological_process +def: "A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex." [GOC:tb] +synonym: "high molecular weight phytochelatin complex formation" RELATED [] +synonym: "HWM phytochelatin complex formation" RELATED [] +is_a: GO:0046937 ! phytochelatin metabolic process +created_by: tb +creation_date: 2012-04-20T03:46:45Z + +[Term] +id: GO:0090425 +name: acinar cell differentiation +namespace: biological_process +def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb] +is_a: GO:0002067 ! glandular epithelial cell differentiation +created_by: tb +creation_date: 2012-05-04T09:24:48Z + +[Term] +id: GO:0090426 +name: actin filament bundle convergence +namespace: biological_process +def: "A process of actin filament bundle distribution that results in the compaction of actin filaments." [GOC:dph, GOC:tb] +is_a: GO:0070650 ! actin filament bundle distribution +created_by: tb +creation_date: 2012-05-04T09:33:09Z + +[Term] +id: GO:0090427 +name: activation of meiosis +namespace: biological_process +def: "Any process that starts the inactive process of meiosis." [GOC:dph, GOC:tb] +is_a: GO:0045836 ! positive regulation of meiotic nuclear division +created_by: tb +creation_date: 2012-05-04T09:50:19Z + +[Term] +id: GO:0090428 +name: perianth development +namespace: biological_process +def: "The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals." [GOC:tb, PO:0009058] +is_a: GO:0048438 ! floral whorl development +created_by: tb +creation_date: 2012-05-08T06:02:15Z + +[Term] +id: GO:0090429 +name: detection of endogenous biotic stimulus +namespace: biological_process +def: "The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal." [GOC:dph, GOC:tb] +is_a: GO:0009595 ! detection of biotic stimulus +is_a: GO:0009726 ! detection of endogenous stimulus +created_by: tb +creation_date: 2012-05-11T09:19:39Z + +[Term] +id: GO:0090430 +name: caffeoyl-CoA: alcohol caffeoyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA." [GOC:pz] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: tb +creation_date: 2012-07-25T10:48:15Z + +[Term] +id: GO:0090431 +name: alkyl caffeate ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate." [GOC:pz] +synonym: "alkyl caffeate ester anabolism" EXACT [GOC:tb] +synonym: "alkyl caffeate ester biosynthesis" EXACT [GOC:tb] +synonym: "alkyl caffeate ester formation" EXACT [GOC:tb] +synonym: "alkyl caffeate ester synthesis" EXACT [GOC:tb] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0009802 ! cinnamic acid ester biosynthetic process +created_by: tb +creation_date: 2012-07-25T11:12:09Z + +[Term] +id: GO:0090432 +name: myristoyl-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA." [GOC:al, PMID:18071249] +synonym: "myristoyl-CoA synthetase activity" EXACT [] +is_a: GO:0004467 ! long-chain fatty acid-CoA ligase activity +created_by: tb +creation_date: 2012-07-25T03:31:31Z + +[Term] +id: GO:0090433 +name: palmitoyl-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA." [GOC:al, PMID:18071249] +synonym: "palmitoyl-CoA synthetase activity" EXACT [] +xref: Reactome:R-HSA-434382 "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell" +is_a: GO:0004467 ! long-chain fatty acid-CoA ligase activity +created_by: tb +creation_date: 2012-07-25T03:31:31Z + +[Term] +id: GO:0090434 +name: oleoyl-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA." [GOC:al, PMID:18071249] +synonym: "oleoyl-CoA synthetase activity" EXACT [] +is_a: GO:0004467 ! long-chain fatty acid-CoA ligase activity +created_by: tb +creation_date: 2012-07-25T03:31:31Z + +[Term] +id: GO:0090435 +name: protein localization to nuclear envelope +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb] +synonym: "protein localization in nuclear envelope" EXACT [] +is_a: GO:0034504 ! protein localization to nucleus +created_by: tb +creation_date: 2012-07-30T01:50:41Z + +[Term] +id: GO:0090436 +name: leaf pavement cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate." [GOC:tb] +is_a: GO:0048468 ! cell development +relationship: part_of GO:0048366 ! leaf development +created_by: tb +creation_date: 2012-07-31T16:08:53Z + +[Term] +id: GO:0090437 +name: socket cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support." [GOC:tb] +is_a: GO:0090627 ! plant epidermal cell differentiation +relationship: part_of GO:0090558 ! plant epidermis development +created_by: tb +creation_date: 2012-07-31T17:01:28Z + +[Term] +id: GO:0090438 +name: camelliol C synthase activity +namespace: molecular_function +def: "Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C." [GOC:tb, PMID:17985917] +synonym: "(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)" EXACT [] +is_a: GO:0016866 ! intramolecular transferase activity +created_by: tb +creation_date: 2012-08-08T15:41:45Z + +[Term] +id: GO:0090439 +name: tetraketide alpha-pyrone synthase activity +namespace: molecular_function +def: "Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A ." [MetaCyc:RXN-12183, PMID:21193570] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: tb +creation_date: 2012-08-09T14:35:06Z + +[Term] +id: GO:0090440 +name: abscisic acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of abscisic acid from one side of a membrane to the other." [GOC:tb] +synonym: "abscisic acid transporter activity" EXACT [] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +relationship: part_of GO:0080168 ! abscisic acid transport +created_by: tb +creation_date: 2012-08-20T14:29:42Z + +[Term] +id: GO:0090441 +name: trehalose biosynthesis in response to heat stress +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:dph, GOC:tb] +synonym: "trehalose biosynthetic process in response to heat stress" EXACT systematic_synonym [GOC:tb] +is_a: GO:0005992 ! trehalose biosynthetic process +is_a: GO:0070414 ! trehalose metabolism in response to heat stress +created_by: tb +creation_date: 2012-08-23T13:53:07Z + +[Term] +id: GO:0090442 +name: trehalose catabolism in response to heat stress +namespace: biological_process +def: "The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." [GOC:dph, GOC:tb] +synonym: "trehalose catabolic process in response to heat stress" EXACT systematic_synonym [GOC:tb] +is_a: GO:0070414 ! trehalose metabolism in response to heat stress +is_a: GO:1903134 ! trehalose catabolic process involved in cellular response to stress +created_by: tb +creation_date: 2012-08-23T13:53:07Z + +[Term] +id: GO:0090443 +name: FAR/SIN/STRIPAK complex +namespace: cellular_component +def: "A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body." [GOC:vw, PMID:21561862, PMID:22119525] +synonym: "FAR complex" RELATED [GOC:vw] +synonym: "SIP complex" EXACT [PMID:22119525] +synonym: "striatin interacting phosphatase and kinase complex" EXACT [GOC:vw] +synonym: "STRIPAK signalling complex" RELATED [GOC:vw] +is_a: GO:0032991 ! protein-containing complex +created_by: tb +creation_date: 2012-08-23T14:20:39Z + +[Term] +id: GO:0090444 +name: regulation of nematode larval development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:17550772] +is_a: GO:0040034 ! regulation of development, heterochronic +is_a: GO:0061062 ! regulation of nematode larval development +created_by: tb +creation_date: 2012-08-24T13:24:43Z + +[Term] +id: GO:0090445 +name: positive regulation of nematode larval development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached." [PMID:17550772] +is_a: GO:0045962 ! positive regulation of development, heterochronic +is_a: GO:0061063 ! positive regulation of nematode larval development +is_a: GO:0090444 ! regulation of nematode larval development, heterochronic +created_by: tb +creation_date: 2012-08-24T13:24:43Z + +[Term] +id: GO:0090446 +name: negative regulation of nematode larval development, heterochronic +namespace: biological_process +def: "Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached." [PMID:17550772] +is_a: GO:0045961 ! negative regulation of development, heterochronic +is_a: GO:0061064 ! negative regulation of nematode larval development +is_a: GO:0090444 ! regulation of nematode larval development, heterochronic +created_by: tb +creation_date: 2012-08-24T13:24:43Z + +[Term] +id: GO:0090447 +name: glycerol-3-phosphate 2-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate." [EC:2.3.1.198] +is_a: GO:0008374 ! O-acyltransferase activity +created_by: tb +creation_date: 2012-08-31T09:23:12Z + +[Term] +id: GO:0090448 +name: glucosinolate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in)." [PMID:22864417] +synonym: "glucosinolate:hydrogen symporter activity" EXACT [] +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +created_by: tb +creation_date: 2012-09-07T16:10:37Z + +[Term] +id: GO:0090449 +name: phloem glucosinolate loading +namespace: biological_process +def: "The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink." [PMID:22864417] +is_a: GO:0110126 ! phloem loading +is_a: GO:1901349 ! glucosinolate transport +created_by: tb +creation_date: 2012-09-07T16:21:22Z + +[Term] +id: GO:0090451 +name: cotyledon boundary formation +namespace: biological_process +def: "The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained." [GOC:tb] +is_a: GO:0090691 ! formation of plant organ boundary +created_by: tb +creation_date: 2012-09-19T10:26:54Z + +[Term] +id: GO:0090452 +name: lithium ion transmembrane transport +namespace: biological_process +def: "The directed movement of lithium ions across a membrane." [GOC:tb] +synonym: "lithium ion import" NARROW [] +synonym: "lithium ion uptake" EXACT [GOC:tb] +is_a: GO:0010351 ! lithium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:04:41Z + +[Term] +id: GO:0090453 +name: aspartate transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of aspartate into the vacuole across the vacuolar membrane." [GOC:tb] +synonym: "vacuolar aspartate import" EXACT [GOC:tb] +is_a: GO:0015740 ! C4-dicarboxylate transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0034487 ! vacuolar amino acid transmembrane transport +is_a: GO:0043090 ! amino acid import +created_by: tb +creation_date: 2012-09-24T14:12:46Z + +[Term] +id: GO:0090454 +name: glutamate transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of glutamate into the vacuole across the vacuolar membrane." [GOC:tb] +synonym: "vacuolar glutamate import" RELATED [GOC:tb] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0015800 ! acidic amino acid transport +is_a: GO:0032975 ! amino acid transmembrane import into vacuole +created_by: tb +creation_date: 2012-09-24T14:12:46Z + +[Term] +id: GO:0090455 +name: ornithine transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of ornithine into the vacuole across the vacuolar membrane." [GOC:tb] +synonym: "vacuolar ornithine import" RELATED [GOC:tb] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015822 ! ornithine transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0043090 ! amino acid import +is_a: GO:0098655 ! cation transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:12:46Z + +[Term] +id: GO:0090459 +name: aspartate homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell." [GOC:tb] +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090460 +name: threonine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of threonine within an organism or cell." [GOC:tb] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090461 +name: glutamate homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell." [GOC:tb] +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090462 +name: ornithine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell." [GOC:tb] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090463 +name: lysine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of lysine within an organism or cell." [GOC:tb] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090464 +name: histidine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of histidine within an organism or cell." [GOC:tb] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090465 +name: arginine homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of arginine within an organism or cell." [GOC:tb] +is_a: GO:0055080 ! cation homeostasis +is_a: GO:0080144 ! amino acid homeostasis +created_by: tb +creation_date: 2012-09-24T14:22:02Z + +[Term] +id: GO:0090470 +name: shoot organ boundary specification +namespace: biological_process +def: "The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained." [PMID:18757555] +is_a: GO:0090691 ! formation of plant organ boundary +created_by: tb +creation_date: 2012-09-24T16:22:03Z + +[Term] +id: GO:0090471 +name: 9,15,9'-tri-cis-zeta-carotene isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene." [EC:5.2.1.12] +synonym: "9,15,9'-tricis-zeta-carotene cis-trans-isomerase" RELATED [] +is_a: GO:0016859 ! cis-trans isomerase activity +created_by: tb +creation_date: 2012-09-24T16:29:49Z + +[Term] +id: GO:0090472 +name: dibasic protein processing +namespace: biological_process +def: "Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein." [GOC:al] +is_a: GO:0016485 ! protein processing +created_by: tb +creation_date: 2012-10-01T10:39:26Z + +[Term] +id: GO:0090473 +name: lys-arg specific dibasic protein processing +namespace: biological_process +def: "Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein." [GOC:al] +is_a: GO:0090472 ! dibasic protein processing +created_by: tb +creation_date: 2012-10-01T10:42:30Z + +[Term] +id: GO:0090474 +name: arg-arg specific dibasic protein processing +namespace: biological_process +def: "Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein." [GOC:al] +is_a: GO:0090472 ! dibasic protein processing +created_by: tb +creation_date: 2012-10-01T10:42:30Z + +[Term] +id: GO:0090475 +name: lys-lys specific dibasic protein processing +namespace: biological_process +def: "Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein." [GOC:al] +is_a: GO:0090472 ! dibasic protein processing +created_by: tb +creation_date: 2012-10-01T10:42:30Z + +[Term] +id: GO:0090480 +name: purine nucleotide-sugar transmembrane transport +namespace: biological_process +alt_id: GO:0036079 +def: "The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:tb] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "purine nucleotide-sugar membrane transport" EXACT [] +synonym: "purine nucleotide-sugar transport" RELATED [] +is_a: GO:0015780 ! nucleotide-sugar transmembrane transport +created_by: tb +creation_date: 2011-12-19T03:22:58Z + +[Term] +id: GO:0090481 +name: pyrimidine nucleotide-sugar transmembrane transport +namespace: biological_process +alt_id: GO:0015781 +def: "The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:tb] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "pyrimidine nucleotide-sugar membrane transport" EXACT [] +synonym: "pyrimidine nucleotide-sugar transport" RELATED [] +is_a: GO:0015780 ! nucleotide-sugar transmembrane transport +created_by: tb +creation_date: 2012-10-01T16:43:54Z + +[Term] +id: GO:0090482 +name: vitamin transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0051183 +def: "Enables the transfer of a vitamin from one side of a membrane to the other." [GOC:tb] +synonym: "vitamin or cofactor transporter activity" BROAD [] +synonym: "vitamin transporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0035461 ! vitamin transmembrane transport +created_by: tb +creation_date: 2012-10-02T16:50:50Z + +[Term] +id: GO:0090483 +name: phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine." [PMID:22988102] +synonym: "cardiolipin synthase" RELATED [GOC:tb] +is_a: GO:0030572 ! phosphatidyltransferase activity +created_by: tb +creation_date: 2012-10-03T14:20:05Z + +[Term] +id: GO:0090485 +name: obsolete chromosome number maintenance +namespace: biological_process +def: "OBSOLETE. The maintenance of the standard number of chromosomes in a cell." [GOC:tb] +comment: The reason for obsoletion is that this term represents a phenotype, and could be captured by other terms such as GO:0007059 chromosome segregation or GO:1903467 negative regulation of mitotic DNA replication initiation. +synonym: "diploidization" RELATED [GOC:tb] +synonym: "haploidization" RELATED [GOC:tb] +is_obsolete: true +consider: GO:0007059 +consider: GO:1903467 +created_by: tb +creation_date: 2012-10-05T11:21:45Z + +[Term] +id: GO:0090486 +name: small RNA 2'-O-methyltransferase +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide." [EC:2.1.1.n8, GOC:tb, GOC:vw] +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity +created_by: tb +creation_date: 2012-10-15T16:32:49Z + +[Term] +id: GO:0090487 +name: secondary metabolite catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:tb] +synonym: "secondary metabolite breakdown" EXACT [GOC:tb] +synonym: "secondary metabolite catabolism" EXACT [GOC:tb] +synonym: "secondary metabolite degradation" EXACT [GOC:tb] +is_a: GO:0009056 ! catabolic process +is_a: GO:0019748 ! secondary metabolic process +created_by: tb +creation_date: 2012-10-15T16:43:09Z + +[Term] +id: GO:0090488 +name: polo box domain specific binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases." [GOC:al, GOC:tb, Pfam:PF00659, PMID:12352953] +is_a: GO:0019904 ! protein domain specific binding +created_by: tb +creation_date: 2012-10-16T10:47:30Z + +[Term] +id: GO:0090489 +name: L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating) +namespace: molecular_function +def: "Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O." [EC:1.14.13.125, KEGG_REACTION:R08160] +synonym: "tryptophan N-monooxygenase activity" RELATED [] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +relationship: has_part GO:0090490 ! L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) +relationship: has_part GO:0090491 ! N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) +relationship: has_part GO:0090492 ! N,N-Dihydroxy-L-tryptophan decarboxylase activity +created_by: tb +creation_date: 2012-10-16T16:22:19Z + +[Term] +id: GO:0090490 +name: L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) +namespace: molecular_function +def: "Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O." [KEGG_REACTION:R09583] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: tb +creation_date: 2012-10-16T16:27:19Z + +[Term] +id: GO:0090491 +name: N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) +namespace: molecular_function +def: "Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O." [KEGG_REACTION:R09584] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: tb +creation_date: 2012-10-16T16:27:19Z + +[Term] +id: GO:0090492 +name: N,N-Dihydroxy-L-tryptophan decarboxylase activity +namespace: molecular_function +def: "Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O." [KEGG_REACTION:R09585] +is_a: GO:0016831 ! carboxy-lyase activity +created_by: tb +creation_date: 2012-10-16T16:32:30Z + +[Term] +id: GO:0090493 +name: catecholamine uptake +namespace: biological_process +def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] +is_a: GO:0051937 ! catecholamine transport +is_a: GO:0098657 ! import into cell +created_by: tb +creation_date: 2012-10-17T11:06:17Z + +[Term] +id: GO:0090494 +name: dopamine uptake +namespace: biological_process +def: "The directed movement of dopamine into a cell." [GOC:dph, GOC:tb] +is_a: GO:0015872 ! dopamine transport +is_a: GO:0090493 ! catecholamine uptake +created_by: tb +creation_date: 2012-10-17T11:12:09Z + +[Term] +id: GO:0090495 +name: low-density lipoprotein particle disassembly +namespace: biological_process +def: "The disaggregation of a low-density lipoprotein particle into its constituent components." [GOC:dph, GOC:tb] +is_a: GO:0071829 ! plasma lipoprotein particle disassembly +created_by: tb +creation_date: 2012-10-17T11:48:56Z + +[Term] +id: GO:0090496 +name: mesenchyme migration involved in limb bud formation +namespace: biological_process +def: "The migration of mesenchymal tissue that contributes to the formation of a limb bud." [GOC:dph, GOC:tb] +is_a: GO:0090131 ! mesenchyme migration +intersection_of: GO:0090131 ! mesenchyme migration +intersection_of: part_of GO:0060174 ! limb bud formation +relationship: part_of GO:0060174 ! limb bud formation +created_by: tb +creation_date: 2012-10-17T12:04:20Z + +[Term] +id: GO:0090497 +name: mesenchymal cell migration +namespace: biological_process +def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb] +is_a: GO:0001667 ! ameboidal-type cell migration +created_by: tb +creation_date: 2012-10-17T12:08:17Z + +[Term] +id: GO:0090498 +name: extrinsic component of Golgi membrane +namespace: cellular_component +def: "The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos, PMID:21337012] +synonym: "extrinsic to Golgi membrane" NARROW [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0000139 ! Golgi membrane +relationship: part_of GO:0000139 ! Golgi membrane +created_by: tb +creation_date: 2012-10-18T14:12:48Z + +[Term] +id: GO:0090499 +name: pimelyl-[acyl-carrier protein] methyl ester esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol." [EC:3.1.1.85, PMID:23045647] +comment: Note that while this reaction occurs on a modified protein (acyl-carrier protein), the ACP only acts as a carrier that later releases the end product. +synonym: "pimelyl-[acyl-carrier protein] methyl ester hydrolase activity" RELATED [] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: tb +creation_date: 2012-10-19T12:10:01Z + +[Term] +id: GO:0090500 +name: endocardial cushion to mesenchymal transition +namespace: biological_process +def: "A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, GOC:tb] +is_a: GO:0060317 ! cardiac epithelial to mesenchymal transition +created_by: tb +creation_date: 2012-10-22T11:51:44Z + +[Term] +id: GO:0090501 +name: RNA phosphodiester bond hydrolysis +namespace: biological_process +def: "The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis." [GOC:dph, GOC:tb] +is_a: GO:0016070 ! RNA metabolic process +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +created_by: tb +creation_date: 2012-10-22T12:05:27Z + +[Term] +id: GO:0090502 +name: RNA phosphodiester bond hydrolysis, endonucleolytic +namespace: biological_process +def: "The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides." [GOC:dph, GOC:tb] +is_a: GO:0090501 ! RNA phosphodiester bond hydrolysis +created_by: tb +creation_date: 2012-10-22T12:05:27Z + +[Term] +id: GO:0090503 +name: RNA phosphodiester bond hydrolysis, exonucleolytic +namespace: biological_process +def: "The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides." [GOC:dph, GOC:tb] +is_a: GO:0090501 ! RNA phosphodiester bond hydrolysis +created_by: tb +creation_date: 2012-10-22T12:05:27Z + +[Term] +id: GO:0090504 +name: epiboly +namespace: biological_process +def: "The expansion of one cell sheet over other cells or yolk." [GOC:dph, GOC:tb] +is_a: GO:0002011 ! morphogenesis of an epithelial sheet +created_by: tb +creation_date: 2012-10-22T12:29:52Z + +[Term] +id: GO:0090505 +name: epiboly involved in wound healing +namespace: biological_process +def: "The expansion of one cell sheet over other cells involved in wound healing." [GOC:dph, GOC:tb] +is_a: GO:0090504 ! epiboly +intersection_of: GO:0090504 ! epiboly +intersection_of: part_of GO:0042060 ! wound healing +relationship: part_of GO:0042060 ! wound healing +created_by: tb +creation_date: 2012-10-22T12:38:51Z + +[Term] +id: GO:0090506 +name: axillary shoot meristem initiation +namespace: biological_process +def: "A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf." [GOC:tb] +synonym: "axillary bud meristem initiation" RELATED [] +is_a: GO:0010014 ! meristem initiation +relationship: part_of GO:0010223 ! secondary shoot formation +created_by: tb +creation_date: 2012-10-23T14:47:00Z + +[Term] +id: GO:0090507 +name: phenylethylamine metabolic process involved in synaptic transmission +namespace: biological_process +def: "The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission." [GOC:tb] +is_a: GO:0042133 ! neurotransmitter metabolic process +is_a: GO:0042443 ! phenylethylamine metabolic process +intersection_of: GO:0042443 ! phenylethylamine metabolic process +intersection_of: part_of GO:0007268 ! chemical synaptic transmission +relationship: part_of GO:0007268 ! chemical synaptic transmission +created_by: tb +creation_date: 2012-11-15T15:06:08Z + +[Term] +id: GO:0090508 +name: phenylethylamine biosynthetic process involved in synaptic transmission +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission." [GOC:tb] +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0042444 ! phenylethylamine biosynthetic process +is_a: GO:0090507 ! phenylethylamine metabolic process involved in synaptic transmission +intersection_of: GO:0042444 ! phenylethylamine biosynthetic process +intersection_of: part_of GO:0007268 ! chemical synaptic transmission +created_by: tb +creation_date: 2012-11-15T15:10:23Z + +[Term] +id: GO:0090510 +name: anticlinal cell division +namespace: biological_process +def: "A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file." [GOC:tair_curators, PMID:21391814] +is_a: GO:0051301 ! cell division +created_by: tb +creation_date: 2012-11-21T11:52:40Z + +[Term] +id: GO:0090511 +name: periclinal cell division +namespace: biological_process +def: "A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file." [GOC:tair_curators, PMID:21391814] +is_a: GO:0051301 ! cell division +created_by: tb +creation_date: 2012-11-21T11:52:40Z + +[Term] +id: GO:0090512 +name: eisosome membrane domain/MCC +namespace: cellular_component +def: "A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins." [GOC:al, GOC:vw, PMID:22368779] +is_a: GO:0044853 ! plasma membrane raft +relationship: part_of GO:0032126 ! eisosome +created_by: tb +creation_date: 2012-12-07T17:00:19Z + +[Term] +id: GO:0090513 +name: L-histidine transmembrane import into vacuole +namespace: biological_process +alt_id: GO:0090457 +def: "The directed movement of L-histidine into the vacuole across the vacuolar membrane." [GOC:al] +synonym: "histidine transmembrane import into vacuole" BROAD [] +synonym: "vacuolar histidine import" BROAD [GOC:tb] +is_a: GO:0034490 ! basic amino acid transmembrane import into vacuole +is_a: GO:0089709 ! L-histidine transmembrane transport +is_a: GO:1902024 ! L-histidine transport +created_by: tb +creation_date: 2012-12-14T11:25:52Z + +[Term] +id: GO:0090514 +name: L-tyrosine transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of L-tyrosine into the vacuole across the vacuolar membrane." [GOC:al] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015828 ! tyrosine transport +is_a: GO:0032975 ! amino acid transmembrane import into vacuole +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: tb +creation_date: 2012-12-14T11:25:52Z + +[Term] +id: GO:0090515 +name: L-glutamate transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of L-glutamate into the vacuole across the vacuolar membrane." [GOC:al] +is_a: GO:0015813 ! L-glutamate transmembrane transport +is_a: GO:0051938 ! L-glutamate import +is_a: GO:0090454 ! glutamate transmembrane import into vacuole +created_by: tb +creation_date: 2012-12-14T11:25:52Z + +[Term] +id: GO:0090516 +name: L-serine transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of L-serine into the vacuole across the vacuolar membrane." [GOC:al] +is_a: GO:0015825 ! L-serine transport +is_a: GO:0034491 ! neutral amino acid transmembrane import into vacuole +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: tb +creation_date: 2012-12-14T11:25:52Z + +[Term] +id: GO:0090517 +name: L-lysine transmembrane import into vacuole +namespace: biological_process +alt_id: GO:0090456 +def: "The directed movement of L-lysine into the vacuole across the vacuolar membrane." [GOC:al] +synonym: "lysine transmembrane import into vacuole" BROAD [] +synonym: "vacuolar lysine import" BROAD [GOC:tb] +is_a: GO:0015819 ! lysine transport +is_a: GO:0034490 ! basic amino acid transmembrane import into vacuole +is_a: GO:1903401 ! L-lysine transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:12:46Z + +[Term] +id: GO:0090518 +name: L-arginine transmembrane import into vacuole +namespace: biological_process +alt_id: GO:0090458 +def: "The directed movement of L-arginine into the vacuole across the vacuolar membrane." [GOC:al] +synonym: "arginine transmembrane import into vacuole" BROAD [] +synonym: "vacuolar arginine import" EXACT [GOC:tb] +is_a: GO:0034490 ! basic amino acid transmembrane import into vacuole +is_a: GO:1903400 ! L-arginine transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:12:46Z + +[Term] +id: GO:0090519 +name: anoxia protection +namespace: biological_process +def: "Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia." [GOC:tb, PMID:19372430] +is_a: GO:0034059 ! response to anoxia +created_by: tb +creation_date: 2012-12-21T15:37:37Z + +[Term] +id: GO:0090520 +name: sphingolipid mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by a sphingolipid." [PMID:9525917] +synonym: "ceramide 1-phosphate signaling pathway" NARROW [PMID:20870412] +synonym: "ceramide signaling pathway" NARROW [PMID:20870412] +synonym: "sphingolipid mediated signal transduction" EXACT [GOC:signaling] +synonym: "sphingolipid signaling pathway" RELATED [] +synonym: "sphingolipid-mediated signaling pathway" EXACT [GOC:signaling] +synonym: "sphingosine signaling pathway" NARROW [PMID:20870412] +is_a: GO:0007165 ! signal transduction +created_by: tb +creation_date: 2013-01-08T09:30:54Z + +[Term] +id: GO:0090521 +name: glomerular visceral epithelial cell migration +namespace: biological_process +def: "The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell." [GOC:pm, PMID:21402783] +synonym: "podocyte cell migration" RELATED [GOC:pm] +is_a: GO:0010631 ! epithelial cell migration +created_by: tb +creation_date: 2013-01-08T11:08:57Z + +[Term] +id: GO:0090522 +name: vesicle tethering involved in exocytosis +namespace: biological_process +def: "The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion." [GOC:rn, PMID:10559876, PMID:17052174, PMID:17488620, PMID:22420621, PMID:27243008] +synonym: "vesicle tethering to plasma membrane" NARROW [] +is_a: GO:0099022 ! vesicle tethering +is_a: GO:0140029 ! exocytic process +intersection_of: GO:0099022 ! vesicle tethering +intersection_of: part_of GO:0006887 ! exocytosis +created_by: tb +creation_date: 2013-01-08T15:07:50Z + +[Term] +id: GO:0090523 +name: cytochrome-b5 reductase activity, acting on NADPH +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5)." [GOC:tb] +synonym: "cytochrome-b5 reductase activity" BROAD [] +is_a: GO:0004128 ! cytochrome-b5 reductase activity, acting on NAD(P)H +created_by: tb +creation_date: 2013-01-11T12:21:41Z + +[Term] +id: GO:0090524 +name: cytochrome-b5 reductase activity, acting on NADH +namespace: molecular_function +def: "Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5)." [GOC:tb] +synonym: "cytochrome b5 reductase activity" BROAD [] +is_a: GO:0004128 ! cytochrome-b5 reductase activity, acting on NAD(P)H +created_by: tb +creation_date: 2013-01-11T12:21:50Z + +[Term] +id: GO:0090527 +name: actin filament reorganization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments." [GOC:dph, GOC:tb] +is_a: GO:0007015 ! actin filament organization +relationship: part_of GO:0031532 ! actin cytoskeleton reorganization +created_by: tb +creation_date: 2013-01-23T10:27:44Z + +[Term] +id: GO:0090528 +name: smooth septate junction assembly +namespace: biological_process +def: "The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions." [PMID:22854041] +is_a: GO:0019991 ! septate junction assembly +created_by: tb +creation_date: 2013-02-05T14:47:40Z + +[Term] +id: GO:0090529 +name: cell septum assembly +namespace: biological_process +alt_id: GO:0090530 +def: "The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." [GOC:mtg_cell_cycle] +synonym: "cell septum assembly involved in cell cycle cytokinesis" EXACT [] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0032506 ! cytokinetic process +created_by: tb +creation_date: 2013-02-06T10:26:38Z + +[Term] +id: GO:0090531 +name: L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose." [GOC:yaf, PMID:11153268] +synonym: "L-ascorbic acid biosynthesis via GDP-alpha-D-mannose" RELATED [] +synonym: "Smirnoff-Wheeler's pathway" RELATED [] +xref: BioCyc:PWY-882 +is_a: GO:0019853 ! L-ascorbic acid biosynthetic process +created_by: tb +creation_date: 2013-02-06T15:31:01Z + +[Term] +id: GO:0090532 +name: L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate." [BioCyc:PWY3DJ-35471, GOC:yaf, PMID:11153268, UniPathway:UPA00991] +comment: This pathway occurs in most vertebrates, although not in guinea pigs and primates, including humans. +synonym: "L-ascorbic acid biosynthesis via UDP-alpha-D-glucuronate" RELATED [] +is_a: GO:0019853 ! L-ascorbic acid biosynthetic process +created_by: tb +creation_date: 2013-02-06T15:31:01Z + +[Term] +id: GO:0090533 +name: cation-transporting ATPase complex +namespace: cellular_component +def: "Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)." [GOC:BHF] +is_a: GO:0098533 ! ATPase dependent transmembrane transport complex +created_by: tb +creation_date: 2013-02-07T15:50:28Z + +[Term] +id: GO:0090534 +name: calcium ion-transporting ATPase complex +namespace: cellular_component +def: "Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in)." [GOC:BHF] +is_a: GO:0090533 ! cation-transporting ATPase complex +created_by: tb +creation_date: 2013-02-07T15:52:58Z + +[Term] +id: GO:0090535 +name: WICH complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair." [GOC:krc, PMID:15284901, PMID:16568949, PMID:21810179] +is_a: GO:0031010 ! ISWI-type complex +created_by: tb +creation_date: 2013-02-11T14:07:14Z + +[Term] +id: GO:0090536 +name: NoRC complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters." [GOC:krc] +is_a: GO:0031010 ! ISWI-type complex +created_by: tb +creation_date: 2013-02-11T14:07:14Z + +[Term] +id: GO:0090537 +name: CERF complex +namespace: cellular_component +def: "An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters." [GOC:krc] +is_a: GO:0031010 ! ISWI-type complex +created_by: tb +creation_date: 2013-02-11T14:07:14Z + +[Term] +id: GO:0090538 +name: peptide pheromone secretion +namespace: biological_process +def: "The regulated release of a peptide pheromone from a cell." [GOC:al, GOC:tb, GOC:vw] +is_a: GO:0000770 ! peptide pheromone export +is_a: GO:0030072 ! peptide hormone secretion +created_by: tb +creation_date: 2013-02-11T15:38:29Z + +[Term] +id: GO:0090539 +name: peptide pheromone export by transmembrane transport +namespace: biological_process +def: "The directed movement of a peptide pheromone across a membrane and out of a cell." [GOC:al, GOC:tb, GOC:vw] +synonym: "peptide pheromone export by membrane transport" EXACT [] +is_a: GO:0000770 ! peptide pheromone export +is_a: GO:0140115 ! export across plasma membrane +created_by: tb +creation_date: 2013-02-11T15:44:51Z + +[Term] +id: GO:0090540 +name: bacterial cellulose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria." [DOI:10.1016/S0268-005X(87)80024-3, DOI:10.1023/A\:1009272904582, GOC:tb, GOC:yaf, UniPathway:UPA00694] +synonym: "bacterial cellulose biosynthesis" EXACT [GOC:yaf] +is_a: GO:0030244 ! cellulose biosynthetic process +created_by: tb +creation_date: 2013-02-11T16:32:44Z + +[Term] +id: GO:0090541 +name: MIT domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking." [GOC:pm, InterPro:IPR007330] +is_a: GO:0019904 ! protein domain specific binding +created_by: tb +creation_date: 2013-02-14T17:11:29Z + +[Term] +id: GO:0090542 +name: ELYC domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the ELYC domain of a protein. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC." [GOC:pm, PMID:18032582, PMID:19525971] +is_a: GO:0019904 ! protein domain specific binding +created_by: tb +creation_date: 2013-02-14T17:11:29Z + +[Term] +id: GO:0090543 +name: Flemming body +namespace: cellular_component +def: "A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge." [GOC:pm, PMID:18641129, PMID:22522702] +synonym: "Midbody ring" RELATED [PMID:18329369] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030496 ! midbody +created_by: tb +creation_date: 2013-02-14T17:24:43Z + +[Term] +id: GO:0090545 +name: CHD-type complex +namespace: cellular_component +def: "A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure." [GOC:krc, GOC:tb, PMID:17350655] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: tb +creation_date: 2013-02-15T12:11:57Z + +[Term] +id: GO:0090546 +name: chlorophyll fluorescence +namespace: biological_process +def: "The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light." [PMID:10938857] +is_a: GO:1990066 ! energy quenching +created_by: tb +creation_date: 2013-03-27T14:23:27Z + +[Term] +id: GO:0090547 +name: response to low humidity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere." [GOC:tb] +is_a: GO:0009270 ! response to humidity +created_by: tb +creation_date: 2013-04-17T13:46:28Z + +[Term] +id: GO:0090548 +name: response to nitrate starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate." [GOC:tair_curators] +is_a: GO:0042594 ! response to starvation +created_by: tb +creation_date: 2013-04-22T13:57:16Z + +[Term] +id: GO:0090549 +name: response to carbon starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source." [GOC:tair_curators, PMID:18245858] +is_a: GO:0042594 ! response to starvation +created_by: tb +creation_date: 2013-04-22T13:57:16Z + +[Term] +id: GO:0090550 +name: response to molybdenum starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum." [GOC:tair_curators] +is_a: GO:0042594 ! response to starvation +created_by: tb +creation_date: 2013-04-22T13:57:16Z + +[Term] +id: GO:0090551 +name: response to manganese starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese." [GOC:tair_curators] +is_a: GO:0042594 ! response to starvation +created_by: tb +creation_date: 2013-04-22T13:57:16Z + +[Term] +id: GO:0090552 +name: unicellular trichome apex +namespace: cellular_component +def: "A cell projection part that is the apical most portion of a unicellular trichome." [GOC:PO_curators, PO:0025537] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0042995 ! cell projection +created_by: tb +creation_date: 2013-04-25T11:56:56Z + +[Term] +id: GO:0090553 +name: unicellular trichome tip +namespace: cellular_component +def: "A cell projection part that is the apical most portion of a unicellular trichome apex." [GOC:PO_curators] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0090552 ! unicellular trichome apex +created_by: tb +creation_date: 2013-04-25T11:56:56Z + +[Term] +id: GO:0090554 +name: phosphatidylcholine floppase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, RHEA:38584] +synonym: "ATP-dependent phosphatidylcholine transporter activity" BROAD [] +synonym: "ATPase-coupled phosphatidylcholine transporter activity" BROAD [] +synonym: "phosphatidylcholine floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "phosphatidylcholine-translocating ATPase activity" BROAD [] +is_a: GO:0008525 ! phosphatidylcholine transporter activity +is_a: GO:0140328 ! floppase activity +created_by: tb +creation_date: 2013-10-24T16:07:20Z + +[Term] +id: GO:0090555 +name: phosphatidylethanolamine flippase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, RHEA:36440] +comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. Some authors however use the names flippases and floppases interchangeably to denote any enzyme catalyzing transbilayer lipid motion, in some cases even in the absence of ATP requirements (PMID 20043909). The direction of the translocation should be taken into account for annotation. +synonym: "ATP-dependent phosphatidylethanolamine transporter activity" RELATED [] +synonym: "ATPase-coupled phosphatidylethanolamine transporter activity" BROAD [] +synonym: "phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +synonym: "phosphatidylethanolamine-translocating ATPase activity" RELATED [] +is_a: GO:0140333 ! glycerophospholipid flippase activity +created_by: tb +creation_date: 2013-10-24T16:07:20Z + +[Term] +id: GO:0090556 +name: phosphatidylserine floppase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, PMID:20224745, RHEA:38568] +synonym: "ATPase-coupled phosphatidylserine transporter activity" BROAD [] +synonym: "ATPase-dependent phosphatidylserine transporter activity" BROAD [] +synonym: "phosphatidylserine floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "phosphatidylserine-translocating ATPase activity" BROAD [] +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0140328 ! floppase activity +created_by: tb +creation_date: 2013-10-24T16:07:20Z + +[Term] +id: GO:0090557 +name: establishment of endothelial intestinal barrier +namespace: biological_process +def: "The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition." [GOC:krc, PMID:22155109] +is_a: GO:0061028 ! establishment of endothelial barrier +created_by: tb +creation_date: 2013-10-29T15:08:27Z + +[Term] +id: GO:0090558 +name: plant epidermis development +namespace: biological_process +def: "The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure." [GOC:tb] +is_a: GO:0009888 ! tissue development +created_by: tb +creation_date: 2014-02-27T15:17:37Z + +[Term] +id: GO:0090559 +name: regulation of membrane permeability +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane." [GOC:kmv, PMID:22677064] +is_a: GO:0065008 ! regulation of biological quality +created_by: tb +creation_date: 2014-03-27T13:48:35Z + +[Term] +id: GO:0090560 +name: 2-(3-amino-3-carboxypropyl)histidine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2]." [BRENDA:2.5.1.108, GOC:pde, PMID:15485916] +xref: MetaCyc:RXN-11371 +xref: Reactome:R-HSA-5358494 "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: tb +creation_date: 2014-03-27T14:58:50Z + +[Term] +id: GO:0090561 +name: nuclear migration during mitotic telophase +namespace: biological_process +def: "The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis." [GOC:vw, PMID:23087209] +is_a: GO:0030473 ! nuclear migration along microtubule +created_by: tb +creation_date: 2014-03-27T15:17:10Z + +[Term] +id: GO:0090562 +name: protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in)." [GOC:am, PMID:10913119] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-04-08T14:55:02Z + +[Term] +id: GO:0090563 +name: protein-phosphocysteine-sugar phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:am] +is_a: GO:0015144 ! carbohydrate transmembrane transporter activity +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0022804 ! active transmembrane transporter activity +created_by: tb +creation_date: 2014-04-08T14:58:00Z + +[Term] +id: GO:0090564 +name: protein-phosphocysteine-glucose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:am] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-04-08T15:03:08Z + +[Term] +id: GO:0090565 +name: protein-phosphocysteine-mannitol phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:am] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-04-08T15:03:08Z + +[Term] +id: GO:0090566 +name: protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in)." [GOC:am, PMID:10913119] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-04-08T15:08:43Z + +[Term] +id: GO:0090567 +name: reproductive shoot system development +namespace: biological_process +def: "The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure." [GOC:pj] +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0048367 ! shoot system development +is_a: GO:0048608 ! reproductive structure development +created_by: tb +creation_date: 2014-04-25T15:42:03Z + +[Term] +id: GO:0090570 +name: RNA polymerase I transcription repressor complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter." [GOC:tb] +is_a: GO:0017053 ! transcription repressor complex +created_by: tb +creation_date: 2014-05-09T13:26:16Z + +[Term] +id: GO:0090571 +name: RNA polymerase II transcription repressor complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter." [GOC:tb] +is_a: GO:0017053 ! transcription repressor complex +created_by: tb +creation_date: 2014-05-09T13:26:16Z + +[Term] +id: GO:0090572 +name: RNA polymerase III transcription repressor complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter." [GOC:tb] +is_a: GO:0017053 ! transcription repressor complex +created_by: tb +creation_date: 2014-05-09T13:26:16Z + +[Term] +id: GO:0090573 +name: RNA polymerase IV transcription repressor complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter." [GOC:tb] +is_a: GO:0017053 ! transcription repressor complex +created_by: tb +creation_date: 2014-05-09T13:26:16Z + +[Term] +id: GO:0090574 +name: RNA polymerase V transcription repressor complex +namespace: cellular_component +def: "A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter." [GOC:tb] +is_a: GO:0017053 ! transcription repressor complex +created_by: tb +creation_date: 2014-05-09T13:26:16Z + +[Term] +id: GO:0090575 +name: RNA polymerase II transcription regulator complex +namespace: cellular_component +def: "A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II." [GOC:tb] +synonym: "RNA polymerase II transcription factor complex" NARROW [] +is_a: GO:0005667 ! transcription regulator complex +created_by: tb +creation_date: 2014-05-09T14:04:37Z + +[Term] +id: GO:0090576 +name: RNA polymerase III transcription regulator complex +namespace: cellular_component +def: "A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III." [GOC:tb] +synonym: "RNA polymerase III transcription factor complex" NARROW [] +is_a: GO:0005667 ! transcription regulator complex +created_by: tb +creation_date: 2014-05-09T14:04:37Z + +[Term] +id: GO:0090577 +name: RNA polymerase IV transcription regulator complex +namespace: cellular_component +def: "A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV." [GOC:tb] +synonym: "RNA polymerase IV transcription factor complex" NARROW [] +is_a: GO:0005667 ! transcription regulator complex +created_by: tb +creation_date: 2014-05-09T14:04:37Z + +[Term] +id: GO:0090578 +name: RNA polymerase V transcription regulator complex +namespace: cellular_component +def: "A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V." [GOC:tb] +synonym: "RNA polymerase V transcription factor complex" NARROW [] +is_a: GO:0005667 ! transcription regulator complex +created_by: tb +creation_date: 2014-05-09T14:04:37Z + +[Term] +id: GO:0090579 +name: dsDNA loop formation +namespace: biological_process +def: "The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule." [GOC:jh, PMID:15950878] +synonym: "chromatin looping" RELATED [GOC:dph] +synonym: "dsDNA looping" EXACT [GOC:dph] +is_a: GO:0051276 ! chromosome organization +created_by: tb +creation_date: 2014-05-12T14:45:58Z + +[Term] +id: GO:0090580 +name: phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +namespace: molecular_function +def: "Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand." [GOC:pde, GOC:rb, PMID:11238902] +is_a: GO:0008081 ! phosphoric diester hydrolase activity +is_a: GO:0140097 ! catalytic activity, acting on DNA +created_by: tb +creation_date: 2014-05-14T15:52:41Z + +[Term] +id: GO:0090581 +name: protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in)." [PMID:14645248] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090582 +name: protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in)." [PMID:8626640] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090583 +name: protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in)." [PMID:8875915] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090584 +name: protein-phosphocysteine-galactitol-phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in)." [PMID:8955298] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090585 +name: protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in)." [PMID:15153772] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090586 +name: protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in)." [PMID:8246840] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090587 +name: protein-phosphocysteine-glucosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in)." [PMID:8246840] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090588 +name: protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in)." [PMID:15060041] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090589 +name: protein-phosphocysteine-trehalose phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in)." [PMID:7608078] +is_a: GO:0090563 ! protein-phosphocysteine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:22:31Z + +[Term] +id: GO:0090590 +name: protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in)." [PMID:8246840] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:33:01Z + +[Term] +id: GO:0090591 +name: protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity +namespace: molecular_function +def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in)." [PMID:9864311] +is_a: GO:0008982 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity +created_by: tb +creation_date: 2014-06-04T16:33:01Z + +[Term] +id: GO:0090592 +name: DNA synthesis involved in DNA replication +namespace: biological_process +def: "Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA." [GOC:vw] +is_a: GO:0071897 ! DNA biosynthetic process +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:0006260 ! DNA replication +relationship: part_of GO:0006260 ! DNA replication +created_by: tb +creation_date: 2014-06-06T13:54:36Z + +[Term] +id: GO:0090593 +name: peptidyl-histidine autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein." [PMID:15947782, PMID:8962061] +is_a: GO:0046777 ! protein autophosphorylation +created_by: tb +creation_date: 2014-06-06T14:19:46Z + +[Term] +id: GO:0090594 +name: inflammatory response to wounding +namespace: biological_process +def: "The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents." [GOC:add] +is_a: GO:0006954 ! inflammatory response +is_a: GO:0009611 ! response to wounding +created_by: tb +creation_date: 2014-08-12T12:13:53Z + +[Term] +id: GO:0090595 +name: acetyl-CoA:L-lysine N6-acetyltransferase +namespace: molecular_function +def: "Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+)." [MetaCyc:LYSACET-RXN] +is_a: GO:0008080 ! N-acetyltransferase activity +created_by: tb +creation_date: 2014-08-21T17:19:06Z + +[Term] +id: GO:0090596 +name: sensory organ morphogenesis +namespace: biological_process +def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0007423 ! sensory organ development +created_by: tb +creation_date: 2014-08-22T13:23:20Z + +[Term] +id: GO:0090597 +name: nematode male tail mating organ morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules." [GOC:kmv, PMID:1782863, PMID:18050419, PMID:7409314] +is_a: GO:0048808 ! male genitalia morphogenesis +is_a: GO:0090596 ! sensory organ morphogenesis +created_by: tb +creation_date: 2014-08-22T13:25:22Z + +[Term] +id: GO:0090598 +name: male anatomical structure morphogenesis +namespace: biological_process +def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0046661 ! male sex differentiation +created_by: tb +creation_date: 2014-08-22T13:29:45Z + +[Term] +id: GO:0090599 +name: alpha-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose." [GOC:tb] +xref: EC:3.2.1.20 +xref: Reactome:R-HSA-9036727 "GAA hydrolyzes lysosomal glycogen" +xref: Reactome:R-HSA-9036729 "Defective GAA does not hydrolyze lysosomal glycogen" +is_a: GO:0015926 ! glucosidase activity +created_by: tb +creation_date: 2014-08-22T14:33:31Z + +[Term] +id: GO:0090600 +name: alpha-1,3-glucosidase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose." [GOC:sd, GOC:tb] +is_a: GO:0090599 ! alpha-glucosidase activity +created_by: tb +creation_date: 2014-08-22T15:00:45Z + +[Term] +id: GO:0090601 +name: enucleation +namespace: biological_process +def: "The process in which nucleated precursor cells lose their nucleus." [GOC:tb] +is_a: GO:0022411 ! cellular component disassembly +created_by: tb +creation_date: 2014-09-05T16:25:16Z + +[Term] +id: GO:0090602 +name: sieve element enucleation +namespace: biological_process +def: "The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded." [GOC:tb, PMID:25081480] +is_a: GO:0090601 ! enucleation +relationship: part_of GO:0090603 ! sieve element differentiation +created_by: tb +creation_date: 2014-09-05T16:25:16Z + +[Term] +id: GO:0090603 +name: sieve element differentiation +namespace: biological_process +def: "The process whereby a relatively unspecialized cell acquires specialized features of a sieve element." [GOC:tb] +is_a: GO:0030154 ! cell differentiation +created_by: tb +creation_date: 2014-09-05T16:38:20Z + +[Term] +id: GO:0090604 +name: surface biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, GOC:tb] +is_a: GO:0042710 ! biofilm formation +created_by: tb +creation_date: 2014-09-16T14:38:45Z + +[Term] +id: GO:0090605 +name: submerged biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, GOC:tb] +synonym: "solid substrate biofilm formation" RELATED [] +is_a: GO:0042710 ! biofilm formation +created_by: tb +creation_date: 2014-09-16T14:44:46Z + +[Term] +id: GO:0090606 +name: single-species surface biofilm formation +namespace: biological_process +alt_id: GO:0032022 +def: "A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface." [GOC:ml] +synonym: "multicellular pellicle formation" RELATED [] +is_a: GO:0044010 ! single-species biofilm formation +is_a: GO:0090604 ! surface biofilm formation +created_by: tb +creation_date: 2014-09-16T14:47:11Z + +[Term] +id: GO:0090607 +name: multi-species surface biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms of different species grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, GOC:tb] +is_a: GO:0044399 ! multi-species biofilm formation +is_a: GO:0090604 ! surface biofilm formation +created_by: tb +creation_date: 2014-09-16T14:49:35Z + +[Term] +id: GO:0090608 +name: multi-species submerged biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms of different species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, GOC:tb] +is_a: GO:0044399 ! multi-species biofilm formation +is_a: GO:0090605 ! submerged biofilm formation +created_by: tb +creation_date: 2014-09-16T14:49:35Z + +[Term] +id: GO:0090609 +name: single-species submerged biofilm formation +namespace: biological_process +def: "A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription." [GOC:di, GOC:tb] +is_a: GO:0044010 ! single-species biofilm formation +is_a: GO:0090605 ! submerged biofilm formation +created_by: tb +creation_date: 2014-09-16T14:55:15Z + +[Term] +id: GO:0090610 +name: bundle sheath cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:tb, PMID:24517883] +is_a: GO:0001708 ! cell fate specification +created_by: tb +creation_date: 2014-09-26T13:17:05Z + +[Term] +id: GO:0090611 +name: ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination." [PMID:22547407] +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process +relationship: has_part GO:0007039 ! protein catabolic process in the vacuole +relationship: has_part GO:0071985 ! multivesicular body sorting pathway +created_by: tb +creation_date: 2014-10-23T15:27:12Z + +[Term] +id: GO:0090612 +name: cAMP deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3." [PMID:24074367] +synonym: "cyclic adenosine monophosphate deaminase activity" EXACT [] +is_a: GO:0019239 ! deaminase activity +created_by: tb +creation_date: 2014-10-23T15:46:42Z + +[Term] +id: GO:0090613 +name: 5'-deoxyadenosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3." [PMID:23968233] +is_a: GO:0019239 ! deaminase activity +created_by: tb +creation_date: 2014-10-23T15:59:38Z + +[Term] +id: GO:0090614 +name: 5'-methylthioadenosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3." [PMID:23968233] +is_a: GO:0019239 ! deaminase activity +created_by: tb +creation_date: 2014-10-23T15:59:38Z + +[Term] +id: GO:0090615 +name: mitochondrial mRNA processing +namespace: biological_process +def: "Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs." [GOC:tb, PMID:25181358] +is_a: GO:0000963 ! mitochondrial RNA processing +is_a: GO:0006397 ! mRNA processing +intersection_of: GO:0006397 ! mRNA processing +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: tb +creation_date: 2014-10-24T12:43:27Z + +[Term] +id: GO:0090616 +name: mitochondrial mRNA 3'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome." [GOC:tb, PMID:25181358] +is_a: GO:0000965 ! mitochondrial RNA 3'-end processing +is_a: GO:0031124 ! mRNA 3'-end processing +is_a: GO:0090615 ! mitochondrial mRNA processing +intersection_of: GO:0031124 ! mRNA 3'-end processing +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: tb +creation_date: 2014-10-24T12:45:08Z + +[Term] +id: GO:0090617 +name: mitochondrial mRNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome." [GOC:tb, PMID:25181358] +is_a: GO:0090615 ! mitochondrial mRNA processing +created_by: tb +creation_date: 2014-10-24T12:45:08Z + +[Term] +id: GO:0090618 +name: DNA clamp unloading +namespace: biological_process +def: "The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates." [GOC:rb, PMID:23499004] +synonym: "PCNA unloading" RELATED [GOC:rb, PMID:23499004] +is_a: GO:0009987 ! cellular process +created_by: tb +creation_date: 2014-10-29T12:57:05Z + +[Term] +id: GO:0090619 +name: meiotic spindle pole +namespace: cellular_component +def: "Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules." [GOC:ha, PMID:18250200] +is_a: GO:0000922 ! spindle pole +relationship: part_of GO:0072687 ! meiotic spindle +created_by: tb +creation_date: 2014-12-16T16:38:34Z + +[Term] +id: GO:0090620 +name: obsolete APC-Cdc20 complex +namespace: cellular_component +def: "OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation." [GOC:vw, PMID:10921876] +comment: This term was made obsolete because it is too fine-grained for GO. Consider Complex Portal EBI-1252490, Anaphase-Promoting Complex variant 2 as an alternate term. +synonym: "APC-fizzy complex" EXACT [GOC:vw] +synonym: "APC-Slp1 complex" EXACT [GOC:vw] +synonym: "mitotic anaphase promotic complex" RELATED [GOC:vw] +is_obsolete: true +consider: GO:0005680 +created_by: tb +creation_date: 2014-12-17T17:01:38Z + +[Term] +id: GO:0090621 +name: obsolete APC-fizzy-related complex +namespace: cellular_component +def: "OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1." [GOC:vw, PMID:10921876] +comment: This term was made obsolete because it is too fine-grained for GO. +synonym: "APC-Hct1/Cdh1 complex" EXACT [GOC:vw] +synonym: "APC-Srw1 complex" EXACT [GOC:vw] +is_obsolete: true +consider: GO:0005680 +created_by: tb +creation_date: 2014-12-17T17:01:38Z + +[Term] +id: GO:0090624 +name: endoribonuclease activity, cleaving miRNA-paired mRNA +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15260970, PMID:19239888] +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters +relationship: part_of GO:0035279 ! mRNA cleavage involved in gene silencing by miRNA +created_by: tb +creation_date: 2015-01-21T16:28:52Z + +[Term] +id: GO:0090625 +name: mRNA cleavage involved in gene silencing by siRNA +namespace: biological_process +def: "The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15260970] +is_a: GO:0098795 ! mRNA cleavage involved in gene silencing +intersection_of: GO:0006379 ! mRNA cleavage +intersection_of: part_of GO:0016246 ! RNA interference +relationship: part_of GO:0016246 ! RNA interference +created_by: tb +creation_date: 2015-01-21T17:15:13Z + +[Term] +id: GO:0090626 +name: plant epidermis morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the plant epidermis are generated and organized." [GOC:tb] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0090558 ! plant epidermis development +created_by: tb +creation_date: 2015-01-29T14:54:03Z + +[Term] +id: GO:0090627 +name: plant epidermal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell." [GOC:tb] +is_a: GO:0030154 ! cell differentiation +created_by: tb +creation_date: 2015-02-05T14:23:28Z + +[Term] +id: GO:0090628 +name: plant epidermal cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed." [GOC:tb] +is_a: GO:0001708 ! cell fate specification +relationship: part_of GO:0090627 ! plant epidermal cell differentiation +created_by: tb +creation_date: 2015-02-06T17:32:21Z + +[Term] +id: GO:0090629 +name: lagging strand initiation +namespace: biological_process +def: "The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started." [GOC:mah, GOC:tb] +is_a: GO:0006259 ! DNA metabolic process +relationship: part_of GO:0006273 ! lagging strand elongation +created_by: tb +creation_date: 2015-02-11T14:37:13Z + +[Term] +id: GO:0090630 +name: activation of GTPase activity +namespace: biological_process +alt_id: GO:0032856 +alt_id: GO:0032857 +alt_id: GO:0032858 +alt_id: GO:0032859 +alt_id: GO:0032860 +alt_id: GO:0032861 +alt_id: GO:0032862 +alt_id: GO:0032863 +alt_id: GO:0032864 +def: "Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] +synonym: "activation of ARF GTPase activity" NARROW [] +synonym: "activation of Cdc42 GTPase activity" NARROW [] +synonym: "activation of Rab GTPase activity" NARROW [] +synonym: "activation of Rac GTPase activity" NARROW [] +synonym: "activation of Ral GTPase activity" NARROW [] +synonym: "activation of Ran GTPase activity" NARROW [] +synonym: "activation of Rap GTPase activity" NARROW [] +synonym: "activation of Ras GTPase activity" NARROW [] +synonym: "activation of Rho GTPase activity" NARROW [] +synonym: "ARF GTPase activation" NARROW [] +synonym: "Cdc42 GTPase activation" NARROW [] +synonym: "Rab GTPase activation" NARROW [] +synonym: "Rac GTPase activation" NARROW [] +synonym: "Ral GTPase activation" NARROW [] +synonym: "Ran GTPase activation" NARROW [] +synonym: "Rap GTPase activation" NARROW [] +synonym: "Ras GTPase activation" NARROW [] +synonym: "Rho GTPase activation" NARROW [] +is_a: GO:0043547 ! positive regulation of GTPase activity +created_by: tb +creation_date: 2015-02-11T16:09:19Z + +[Term] +id: GO:0090632 +name: N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc." [ISBN:978-1-60805-067-3, PMID:11479279, PMID:8381411] +synonym: "CMP-Neu5Gc synthetase activity" EXACT [] +is_a: GO:0070567 ! cytidylyltransferase activity +property_value: RO:0002161 NCBITaxon:9606 +created_by: tb +creation_date: 2015-03-19T15:05:54Z + +[Term] +id: GO:0090633 +name: keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN." [ISBN:978-1-60805-067-3, PMID:11479279, PMID:8381411] +synonym: "CMP-KDN synthetase activity" EXACT [] +synonym: "cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity" EXACT [] +is_a: GO:0070567 ! cytidylyltransferase activity +created_by: tb +creation_date: 2015-03-19T15:05:54Z + +[Term] +id: GO:0090634 +name: microglial cell mediated cytotoxicity +namespace: biological_process +def: "The directed killing of a target cell by a microglial cell." [GOC:BHF, GOC:nc, PMID:19100238] +is_a: GO:0001909 ! leukocyte mediated cytotoxicity +is_a: GO:0002444 ! myeloid leukocyte mediated immunity +created_by: tb +creation_date: 2015-04-14T14:04:54Z + +[Term] +id: GO:0090635 +name: extracellular core region of desmosome +namespace: cellular_component +def: "The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner." [PMID:20066089] +synonym: "desmoglea" EXACT [PMID:20066089] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030057 ! desmosome +created_by: tb +creation_date: 2015-04-20T16:10:51Z + +[Term] +id: GO:0090636 +name: outer dense plaque of desmosome +namespace: cellular_component +def: "The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane." [PMID:20066089] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030057 ! desmosome +created_by: tb +creation_date: 2015-04-20T16:10:51Z + +[Term] +id: GO:0090637 +name: inner dense plaque of desmosome +namespace: cellular_component +def: "The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane." [PMID:20066089] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030057 ! desmosome +created_by: tb +creation_date: 2015-04-20T16:10:51Z + +[Term] +id: GO:0090638 +name: phosphatidylcholine biosynthesis from phosphatidylethanolamine +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations." [MetaCyc:PWY-6825] +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2015-04-23T15:56:12Z + +[Term] +id: GO:0090639 +name: phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine." [MetaCyc:PWY-6826] +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2015-04-23T15:56:12Z + +[Term] +id: GO:0090640 +name: phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine +namespace: biological_process +def: "The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine." [MetaCyc:PWY-7470, PMID:24329598, PMID:27758859] +is_a: GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2015-04-23T15:56:12Z + +[Term] +id: GO:0090641 +name: microsporidian-type endospore +namespace: cellular_component +def: "The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins." [PMID:19457051] +comment: Microsporidian biology uses the term endospore differently than GO:0043593 endospore coat which is for a spore formed inside of another cell. Microsporidian endospore refers to the inner layer of the spore wall itself. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031160 ! spore wall +created_by: tb +creation_date: 2015-05-04T14:17:06Z + +[Term] +id: GO:0090642 +name: microsporidian-type exospore +namespace: cellular_component +def: "The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore." [PMID:19457051, PMID:25363531] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031160 ! spore wall +created_by: tb +creation_date: 2015-05-04T14:17:06Z + +[Term] +id: GO:0090643 +name: inflorescence phyllotactic patterning +namespace: biological_process +def: "The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem." [PMID:25352850] +is_a: GO:0060771 ! phyllotactic patterning +created_by: tb +creation_date: 2015-05-05T14:25:09Z + +[Term] +id: GO:0090644 +name: age-related resistance +namespace: biological_process +def: "An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR)." [PMID:17635216, PMID:19694953] +synonym: "adult seedling resistance" NARROW [] +synonym: "ARR" EXACT [] +synonym: "developmental resistance" BROAD [] +synonym: "flowering-induced resistance" NARROW [] +synonym: "mature seedling resistance" NARROW [] +synonym: "ontogenic resistance" BROAD [] +synonym: "senescence-induced resistance" NARROW [] +is_a: GO:0032502 ! developmental process +is_a: GO:0045087 ! innate immune response +created_by: tb +creation_date: 2015-05-19T10:36:38Z + +[Term] +id: GO:0090646 +name: mitochondrial tRNA processing +namespace: biological_process +def: "The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion." [GOC:vw] +is_a: GO:0000963 ! mitochondrial RNA processing +is_a: GO:0008033 ! tRNA processing +created_by: tb +creation_date: 2015-06-12T15:57:13Z + +[Term] +id: GO:0090647 +name: modulation of age-related behavioral decline +namespace: biological_process +def: "Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory." [GOC:cjm, GOC:kmv, PMID:20523893] +is_a: GO:0065008 ! regulation of biological quality +relationship: part_of GO:0007568 ! aging +created_by: tb +creation_date: 2015-06-15T12:45:44Z + +[Term] +id: GO:0090648 +name: response to environmental enrichment +namespace: biological_process +def: "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment." [GOC:sl, PMID:23644055, PMID:25934034] +synonym: "response to the introduction of novel objects" NARROW [] +is_a: GO:0009605 ! response to external stimulus +created_by: tb +creation_date: 2015-07-01T10:20:37Z + +[Term] +id: GO:0090649 +name: response to oxygen-glucose deprivation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose." [GOC:sl, PMID:21525936] +synonym: "response to OGD" EXACT [GOC:sl] +is_a: GO:0031667 ! response to nutrient levels +is_a: GO:0036293 ! response to decreased oxygen levels +created_by: tb +creation_date: 2015-07-01T10:27:29Z + +[Term] +id: GO:0090650 +name: cellular response to oxygen-glucose deprivation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose." [GOC:sl, PMID:21525936] +synonym: "cellular response to OGD" EXACT [GOC:sl] +is_a: GO:0031669 ! cellular response to nutrient levels +is_a: GO:0036294 ! cellular response to decreased oxygen levels +is_a: GO:0090649 ! response to oxygen-glucose deprivation +created_by: tb +creation_date: 2015-07-01T10:27:29Z + +[Term] +id: GO:0090651 +name: apical cytoplasm +namespace: cellular_component +def: "The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells." [PMID:17494872] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0045177 ! apical part of cell +created_by: tb +creation_date: 2015-07-01T15:46:19Z + +[Term] +id: GO:0090652 +name: basolateral cytoplasm +namespace: cellular_component +def: "The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells." [PMID:17494872] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: tb +creation_date: 2015-07-01T15:46:19Z + +[Term] +id: GO:0090653 +name: apical recycling endosome +namespace: cellular_component +def: "Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells." [PMID:12669082, PMID:16394106, PMID:17494872, PMID:21170358, PMID:9405315] +is_a: GO:0055037 ! recycling endosome +relationship: part_of GO:0090651 ! apical cytoplasm +created_by: tb +creation_date: 2015-07-01T15:46:19Z + +[Term] +id: GO:0090654 +name: basolateral recycling endosome +namespace: cellular_component +def: "Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells." [PMID:11389442, PMID:16394106, PMID:17494872, PMID:21170358, PMID:9405315] +is_a: GO:0055037 ! recycling endosome +relationship: part_of GO:0090652 ! basolateral cytoplasm +created_by: tb +creation_date: 2015-07-01T15:46:19Z + +[Term] +id: GO:0090655 +name: double-stranded/single-stranded junction telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang." [GOC:BHF, GOC:BHF_telomere, GOC:bhm, GOC:nc, PMID:21852327] +is_a: GO:0000406 ! double-strand/single-strand DNA junction binding +is_a: GO:0042162 ! telomeric DNA binding +created_by: tb +creation_date: 2015-07-02T11:33:39Z + +[Term] +id: GO:0090656 +name: t-circle formation +namespace: biological_process +def: "A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD)." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:19214183, PMID:19581589, PMID:19809492, PMID:19858100] +synonym: "telomeric circle formation" EXACT [] +is_a: GO:0001325 ! formation of extrachromosomal circular DNA +relationship: part_of GO:0090737 ! telomere maintenance via telomere trimming +created_by: tb +creation_date: 2015-07-02T11:44:23Z + +[Term] +id: GO:0090657 +name: telomeric loop disassembly +namespace: biological_process +def: "The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:22579284] +synonym: "T loop disassembly" EXACT [] +synonym: "t-loop disassembly" EXACT [] +is_a: GO:0000723 ! telomere maintenance +created_by: tb +creation_date: 2015-07-07T13:53:40Z + +[Term] +id: GO:0090658 +name: cone matrix sheath +namespace: cellular_component +def: "A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments." [GOC:mr, PMID:2055688] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0033165 ! interphotoreceptor matrix +created_by: tb +creation_date: 2015-07-15T13:35:32Z + +[Term] +id: GO:0090659 +name: walking behavior +namespace: biological_process +def: "The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg." [GOC:tb] +synonym: "locomotor gait pattern" NARROW [] +is_a: GO:0007626 ! locomotory behavior +created_by: tb +creation_date: 2015-08-27T16:34:28Z + +[Term] +id: GO:0090660 +name: cerebrospinal fluid circulation +namespace: biological_process +def: "The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional." [GOC:mgi_curators, PMID:22100360, PMID:24229449] +synonym: "cerebrospinal fluid flow" EXACT [] +synonym: "CSF circulation" EXACT [] +synonym: "CSF flow" EXACT [] +is_a: GO:0003351 ! epithelial cilium movement involved in extracellular fluid movement +is_a: GO:0050877 ! nervous system process +created_by: tb +creation_date: 2015-09-11T15:49:59Z + +[Term] +id: GO:0090661 +name: box H/ACA telomerase RNP complex +namespace: cellular_component +def: "A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell." [GOC:BHF, GOC:BHF_telomere, GOC:jbu, PMID:22527283] +is_a: GO:0072588 ! box H/ACA RNP complex +relationship: part_of GO:0005697 ! telomerase holoenzyme complex +created_by: tb +creation_date: 2015-09-21T14:46:16Z + +[Term] +id: GO:0090663 +name: galanin-activated signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor." [GOC:lb, PMID:25691535] +synonym: "galanin signaling pathway" RELATED [] +synonym: "galanin signalling pathway" RELATED [] +synonym: "galanin-activated signalling pathway" EXACT [] +is_a: GO:0007218 ! neuropeptide signaling pathway +created_by: tb +creation_date: 2015-10-21T13:38:04Z + +[Term] +id: GO:0090664 +name: response to high population density +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area." [GOC:mr, PMID:26439857] +synonym: "response to crowding" EXACT [GOC:mr] +is_a: GO:0006950 ! response to stress +is_a: GO:0032501 ! multicellular organismal process +created_by: tb +creation_date: 2015-10-21T16:00:30Z + +[Term] +id: GO:0090665 +name: glycoprotein complex +namespace: cellular_component +def: "A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds." [GOC:pf, PMID:7693675, PMID:8662961] +comment: An example is the Dictyostelium multi protein pspB complex, which is secreted from prespore vesicles and incorporated into the spore coat. +is_a: GO:0032991 ! protein-containing complex +created_by: tb +creation_date: 2015-12-11T17:45:23Z + +[Term] +id: GO:0090666 +name: scaRNA localization to Cajal body +namespace: biological_process +def: "A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444] +is_a: GO:0090670 ! RNA localization to Cajal body +created_by: tb +creation_date: 2015-12-15T10:57:05Z + +[Term] +id: GO:0090667 +name: cell chemotaxis to vascular endothelial growth factor +namespace: biological_process +def: "The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF)." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:21885851] +is_a: GO:0060326 ! cell chemotaxis +relationship: part_of GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +created_by: tb +creation_date: 2015-12-15T11:27:12Z + +[Term] +id: GO:0090668 +name: endothelial cell chemotaxis to vascular endothelial growth factor +namespace: biological_process +def: "The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF)." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:21885851] +is_a: GO:0090667 ! cell chemotaxis to vascular endothelial growth factor +created_by: tb +creation_date: 2015-12-15T11:31:43Z + +[Term] +id: GO:0090669 +name: telomerase RNA stabilization +namespace: biological_process +def: "Prevention of degradation of telomerase RNA (TERC) molecules." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444] +synonym: "TERC stabilization" EXACT [] +is_a: GO:0043489 ! RNA stabilization +created_by: tb +creation_date: 2015-12-17T14:01:11Z + +[Term] +id: GO:0090670 +name: RNA localization to Cajal body +namespace: biological_process +def: "A process in which an RNA is transported to, or maintained in, a Cajal body." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444] +is_a: GO:0090685 ! RNA localization to nucleus +created_by: tb +creation_date: 2015-12-17T14:04:40Z + +[Term] +id: GO:0090671 +name: telomerase RNA localization to Cajal body +namespace: biological_process +def: "A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444] +is_a: GO:0090670 ! RNA localization to Cajal body +is_a: GO:0090672 ! telomerase RNA localization +created_by: tb +creation_date: 2015-12-17T14:06:21Z + +[Term] +id: GO:0090672 +name: telomerase RNA localization +namespace: biological_process +def: "Any process in which telomerase RNA is transported to, or maintained in, a specific location." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444] +is_a: GO:0006403 ! RNA localization +created_by: tb +creation_date: 2015-12-17T14:08:01Z + +[Term] +id: GO:0090673 +name: endothelial cell-matrix adhesion +namespace: biological_process +def: "The binding of an endothelial cell to the extracellular matrix via adhesion molecules." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:19460962] +is_a: GO:0007160 ! cell-matrix adhesion +created_by: tb +creation_date: 2016-01-15T15:38:11Z + +[Term] +id: GO:0090674 +name: endothelial cell-matrix adhesion via fibronectin +namespace: biological_process +def: "The binding of an endothelial cell to the extracellular matrix via fibronectin." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:19460962] +is_a: GO:0090673 ! endothelial cell-matrix adhesion +created_by: tb +creation_date: 2016-01-15T15:40:58Z + +[Term] +id: GO:0090675 +name: intermicrovillar adhesion +namespace: biological_process +def: "The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin." [GOC:lb, PMID:24725409] +is_a: GO:0022610 ! biological adhesion +relationship: part_of GO:1904970 ! brush border assembly +created_by: tb +creation_date: 2016-02-19T13:34:07Z + +[Term] +id: GO:0090676 +name: calcium ion transmembrane transport via low voltage-gated calcium channel +namespace: biological_process +def: "A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel." [GOC:bf, GOC:PARL, PMID:20371816] +synonym: "generation of T-type calcium current" RELATED [] +is_a: GO:0070588 ! calcium ion transmembrane transport +relationship: has_part GO:0008332 ! low voltage-gated calcium channel activity +created_by: tb +creation_date: 2016-03-23T10:15:23Z + +[Term] +id: GO:0090677 +name: reversible differentiation +namespace: biological_process +def: "A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another." [GOC:curators] +is_a: GO:0036166 ! phenotypic switching +created_by: tb +creation_date: 2016-04-28T17:32:40Z + +[Term] +id: GO:0090678 +name: cell dedifferentiation involved in phenotypic switching +namespace: biological_process +def: "A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations." [GOC:curators] +is_a: GO:0043697 ! cell dedifferentiation +relationship: part_of GO:0090677 ! reversible differentiation +created_by: tb +creation_date: 2016-04-28T17:32:40Z + +[Term] +id: GO:0090679 +name: cell differentiation involved in phenotypic switching +namespace: biological_process +def: "A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations." [GOC:curators] +is_a: GO:0030154 ! cell differentiation +intersection_of: GO:0030154 ! cell differentiation +intersection_of: part_of GO:0090677 ! reversible differentiation +relationship: part_of GO:0090677 ! reversible differentiation +created_by: tb +creation_date: 2016-04-28T17:32:40Z + +[Term] +id: GO:0090680 +name: disruption by virus of host outer membrane +namespace: biological_process +def: "A process by which a virus has a negative effect on the functioning of a host outer membrane." [PMID:17900620] +is_a: GO:0044662 ! disruption by virus of host cell membrane +created_by: tb +creation_date: 2016-05-04T15:52:02Z + +[Term] +id: GO:0090681 +name: GPCR taste receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor activity that is responsible for the sense of taste." [GOC:hat, GOC:tb] +synonym: "G-protein coupled taste receptor activity" EXACT [] +synonym: "G-protein-coupled taste receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0008527 ! taste receptor activity +created_by: tb +creation_date: 2016-05-20T15:47:18Z + +[Term] +id: GO:0090682 +name: GPCR bitter taste receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor activity that is responsible for the sense of bitter taste." [GOC:hat, GOC:tb] +synonym: "G protein-coupled receptor bitter taste receptor activity" EXACT [] +synonym: "G-protein coupled receptor bitter taste receptor activity" EXACT [] +is_a: GO:0033038 ! bitter taste receptor activity +is_a: GO:0090681 ! GPCR taste receptor activity +created_by: tb +creation_date: 2016-05-20T15:49:18Z + +[Term] +id: GO:0090683 +name: GPCR sweet taste receptor activity +namespace: molecular_function +def: "A G protein-coupled receptor activity that is responsible for the sense of sweet taste." [GOC:hat, GOC:tb] +synonym: "G-protein coupled receptor sweet taste receptor activity" EXACT [] +is_a: GO:0033041 ! sweet taste receptor activity +is_a: GO:0090681 ! GPCR taste receptor activity +created_by: tb +creation_date: 2016-05-20T15:49:18Z + +[Term] +id: GO:0090684 +name: contact chemoreceptor activity +namespace: molecular_function +def: "A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception." [GOC:hat, GOC:tb] +synonym: "contact chemosensation receptor activity" EXACT [] +is_a: GO:0008527 ! taste receptor activity +created_by: tb +creation_date: 2016-05-20T15:53:01Z + +[Term] +id: GO:0090685 +name: RNA localization to nucleus +namespace: biological_process +def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931] +synonym: "RNA localisation to nucleus" EXACT [GOC:mah] +is_a: GO:0006403 ! RNA localization +created_by: tb +creation_date: 2016-07-19T17:00:49Z + +[Term] +id: GO:0090686 +name: glycine betaine-activated nonselective monovalent cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts." [GOC:kmv, PMID:24212673] +is_a: GO:0099094 ! ligand-gated cation channel activity +created_by: tb +creation_date: 2016-07-20T16:29:01Z + +[Term] +id: GO:0090687 +name: activation of meiosis I spindle assembly checkpoint +namespace: biological_process +def: "Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint." [GOC:mah] +is_a: GO:1905326 ! positive regulation of meiosis I spindle assembly checkpoint +created_by: tb +creation_date: 2016-07-20T16:49:17Z + +[Term] +id: GO:0090688 +name: cleavage furrow rim +namespace: cellular_component +def: "The part of the cleavage furrow closest to the cell surface." [GOC:vw, PMID:27082518] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032154 ! cleavage furrow +created_by: tb +creation_date: 2016-07-26T16:00:10Z + +[Term] +id: GO:0090689 +name: cleavage furrow leading edge +namespace: cellular_component +def: "The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring." [GOC:vw, PMID:27082518] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032154 ! cleavage furrow +created_by: tb +creation_date: 2016-07-26T16:00:10Z + +[Term] +id: GO:0090690 +name: obsolete heteroreceptor complex +namespace: cellular_component +def: "OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function." [GOC:pad, GOC:PARL, PMID:22035699, PMID:24157794] +comment: This term was obsoleted as it was created in error. +is_obsolete: true +created_by: tb +creation_date: 2016-08-24T09:47:15Z + +[Term] +id: GO:0090691 +name: formation of plant organ boundary +namespace: biological_process +def: "The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:tb] +is_a: GO:0048859 ! formation of anatomical boundary +created_by: tb +creation_date: 2016-08-24T10:16:28Z + +[Term] +id: GO:0090692 +name: mitochondrial membrane scission site +namespace: cellular_component +def: "The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission." [GOC:bc, GOC:PARL, PMID:26618722] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031966 ! mitochondrial membrane +created_by: tb +creation_date: 2016-08-24T10:46:09Z + +[Term] +id: GO:0090693 +name: plant organ senescence +namespace: biological_process +def: "The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism." [GOC:tb] +is_a: GO:0007568 ! aging +relationship: part_of GO:0099402 ! plant organ development +created_by: tb +creation_date: 2016-08-24T10:50:29Z + +[Term] +id: GO:0090694 +name: Scc2-Scc4 cohesin loading complex +namespace: cellular_component +def: "A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA." [GOC:vw, PMID:24291789] +synonym: "Mis4-Ssl3 cohesin loading complex" EXACT [GOC:vw] +is_a: GO:0032116 ! SMC loading complex +created_by: tb +creation_date: 2016-08-24T17:09:11Z + +[Term] +id: GO:0090695 +name: Wpl/Pds5 cohesin loading/unloading complex +namespace: cellular_component +def: "A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA." [GOC:vw, PMID:26687354] +is_a: GO:0032116 ! SMC loading complex +created_by: tb +creation_date: 2016-08-24T17:09:11Z + +[Term] +id: GO:0090696 +name: post-embryonic plant organ development +namespace: biological_process +def: "Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:tb] +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0099402 ! plant organ development +created_by: tb +creation_date: 2016-08-25T16:35:55Z + +[Term] +id: GO:0090697 +name: post-embryonic plant organ morphogenesis +namespace: biological_process +def: "Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:tb] +is_a: GO:0090698 ! post-embryonic plant morphogenesis +is_a: GO:1905392 ! plant organ morphogenesis +relationship: part_of GO:0090696 ! post-embryonic plant organ development +created_by: tb +creation_date: 2016-08-25T17:04:35Z + +[Term] +id: GO:0090698 +name: post-embryonic plant morphogenesis +namespace: biological_process +def: "The process, occurring after plant embryonic development, by which anatomical structures are generated and organized." [GOC:tb] +is_a: GO:0009653 ! anatomical structure morphogenesis +property_value: RO:0002161 NCBITaxon:4751 +created_by: tb +creation_date: 2016-08-25T17:08:33Z + +[Term] +id: GO:0090699 +name: repair of merotelic kinetochore attachment defect, meiosis I +namespace: biological_process +def: "The cell cycle process that corrects the anomalous association of a single chromatid kinetochore with meiotic spindle microtubules emanating from both spindle poles at meiosis I." [GOC:vw, PMID:21920317] +synonym: "correction of merotelic kinetochore attachment, meiosis I" EXACT [] +is_a: GO:0140274 ! repair of kinetochore microtubule attachment defect +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0043060 ! meiotic metaphase I plate congression +created_by: tb +creation_date: 2016-08-29T14:03:26Z + +[Term] +id: GO:0090700 +name: maintenance of plant organ identity +namespace: biological_process +def: "The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb, PMID:9090883] +is_a: GO:0045596 ! negative regulation of cell differentiation +relationship: part_of GO:0099402 ! plant organ development +created_by: tb +creation_date: 2016-08-29T15:01:08Z + +[Term] +id: GO:0090701 +name: specification of plant organ identity +namespace: biological_process +def: "The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:1905393 ! plant organ formation +created_by: tb +creation_date: 2016-08-29T15:09:18Z + +[Term] +id: GO:0090702 +name: non-reproductive fruiting body development +namespace: biological_process +def: "The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies." [GOC:pf] +is_a: GO:0099120 ! socially cooperative development +created_by: tb +creation_date: 2016-09-09T16:14:21Z + +[Term] +id: GO:0090703 +name: obsolete triplex DNA unwinding +namespace: biological_process +def: "OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'." [PMID:26503245] +comment: This term was made obsolete because it was created in error. +is_obsolete: true +created_by: tb +creation_date: 2016-09-20T16:37:15Z + +[Term] +id: GO:0090704 +name: nicotinate-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP." [GOC:tb, PMID:26116607] +is_a: GO:0035251 ! UDP-glucosyltransferase activity +created_by: tb +creation_date: 2016-09-21T12:46:21Z + +[Term] +id: GO:0090705 +name: trichome papilla +namespace: cellular_component +def: "A plant cell papilla that is part of a trichome cell." [GOC:tb, PMID:24014871] +comment: Part of trichome cell (PO:0008030). +is_a: GO:0090395 ! plant cell papilla +created_by: tb +creation_date: 2016-09-26T12:49:36Z + +[Term] +id: GO:0090706 +name: specification of plant organ position +namespace: biological_process +def: "The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ." [GOC:tb, PMID:9611175] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-10-05T12:33:21Z + +[Term] +id: GO:0090707 +name: establishment of plant organ orientation +namespace: biological_process +def: "The process that determines the orientation of a plant organ or tissue with reference to an axis." [GOC:tb] +is_a: GO:0048560 ! establishment of anatomical structure orientation +relationship: part_of GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-10-05T12:42:47Z + +[Term] +id: GO:0090708 +name: specification of plant organ axis polarity +namespace: biological_process +def: "The process in which the polarity of a plant organ axis is specified." [GOC:tb] +is_a: GO:0065001 ! specification of axis polarity +relationship: part_of GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-10-05T12:47:11Z + +[Term] +id: GO:0090709 +name: regulation of timing of plant organ formation +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development." [GOC:tb] +is_a: GO:0040034 ! regulation of development, heterochronic +is_a: GO:1905428 ! regulation of plant organ formation +created_by: tb +creation_date: 2016-10-05T12:49:58Z + +[Term] +id: GO:0090710 +name: phosphomevalonate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate." [EC:4.1.1.99, MetaCyc:RXN-10067, PMID:24375100] +is_a: GO:0016831 ! carboxy-lyase activity +created_by: tb +creation_date: 2016-10-21T15:59:34Z + +[Term] +id: GO:0090711 +name: FMN hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: FMN + H2O = riboflavin + phosphate." [EC:3.1.3.102, PMID:16183635] +is_a: GO:0016791 ! phosphatase activity +created_by: tb +creation_date: 2016-10-21T16:27:34Z + +[Term] +id: GO:0090712 +name: basal pole of outer hair cell +namespace: cellular_component +def: "The end of the outer hair cell which receives and transmits neural signals." [GOC:sl, PMID:12845523] +is_a: GO:0060187 ! cell pole +created_by: tb +creation_date: 2016-11-01T12:57:03Z + +[Term] +id: GO:0090713 +name: immunological memory process +namespace: biological_process +def: "Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory." [GOC:add, PMID:26086132, PMID:26831526] +is_a: GO:0002376 ! immune system process +relationship: part_of GO:0006955 ! immune response +created_by: tb +creation_date: 2016-11-11T12:20:30Z + +[Term] +id: GO:0090714 +name: innate immunity memory response +namespace: biological_process +def: "An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus." [GOC:add, PMID:26086132] +is_a: GO:0045087 ! innate immune response +is_a: GO:0090713 ! immunological memory process +created_by: tb +creation_date: 2016-11-11T12:23:03Z + +[Term] +id: GO:0090715 +name: immunological memory formation process +namespace: biological_process +def: "Any immunological memory process that can contribute to the formation of immunological memory." [GOC:add, PMID:26086132, PMID:26831526] +is_a: GO:0090713 ! immunological memory process +created_by: tb +creation_date: 2016-11-11T12:25:47Z + +[Term] +id: GO:0090716 +name: adaptive immune memory response +namespace: biological_process +def: "An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response." [GOC:add, PMID:26831526] +is_a: GO:0002250 ! adaptive immune response +is_a: GO:0090713 ! immunological memory process +created_by: tb +creation_date: 2016-11-11T12:32:42Z + +[Term] +id: GO:0090717 +name: adaptive immune memory response involving T cells and B cells +namespace: biological_process +def: "An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response." [GOC:add, PMID:26831526] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0090716 ! adaptive immune memory response +created_by: tb +creation_date: 2016-11-11T12:35:19Z + +[Term] +id: GO:0090718 +name: adaptive immune effector response +namespace: biological_process +def: "An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response." [GOC:add, ISBN:1405196831] +is_a: GO:0002250 ! adaptive immune response +relationship: has_part GO:0002252 ! immune effector process +created_by: tb +creation_date: 2016-11-11T12:37:26Z + +[Term] +id: GO:0090719 +name: adaptive immune effector response involving T cells and B lineage cells +namespace: biological_process +def: "An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells." [GOC:add, ISBN:1405196831] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0090718 ! adaptive immune effector response +created_by: tb +creation_date: 2016-11-11T12:43:26Z + +[Term] +id: GO:0090720 +name: primary adaptive immune response +namespace: biological_process +def: "An adaptive immune response against an antigen not previously encountered by immune system." [GOC:add, PMID:26831526] +is_a: GO:0002250 ! adaptive immune response +created_by: tb +creation_date: 2016-11-11T12:44:55Z + +[Term] +id: GO:0090721 +name: primary adaptive immune response involving T cells and B cells +namespace: biological_process +def: "An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system." [GOC:add, PMID:26831526] +is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:0090720 ! primary adaptive immune response +created_by: tb +creation_date: 2016-11-11T12:46:29Z + +[Term] +id: GO:0090722 +name: receptor-receptor interaction +namespace: molecular_function +def: "The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function." [GOC:dox, GOC:pad, GOC:PARL, PMID:22035699, PMID:24157794] +synonym: "hetero-receptor complex formation" EXACT [] +is_a: GO:0005102 ! signaling receptor binding +created_by: tb +creation_date: 2016-11-11T17:41:56Z + +[Term] +id: GO:0090723 +name: obsolete growth cone part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite." [GOC:sl, GOC:tb] +is_obsolete: true +consider: GO:0030426 +created_by: tb +creation_date: 2016-11-18T09:36:19Z + +[Term] +id: GO:0090724 +name: central region of growth cone +namespace: cellular_component +def: "The center of the migrating motile tip of a growing nerve cell axon or dendrite." [GOC:sl, PMID:16260607] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030426 ! growth cone +created_by: tb +creation_date: 2016-11-18T12:44:25Z + +[Term] +id: GO:0090725 +name: peripheral region of growth cone +namespace: cellular_component +def: "The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite." [GOC:sl, PMID:16260607] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030426 ! growth cone +created_by: tb +creation_date: 2016-11-18T12:44:25Z + +[Term] +id: GO:0090726 +name: cortical dynamic polarity patch +namespace: cellular_component +def: "A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation." [GOC:mah, PMID:23200991] +synonym: "dynamic polarity patch at the cell cortex" EXACT [GOC:mah] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005938 ! cell cortex +created_by: tb +creation_date: 2016-11-22T16:17:02Z + +[Term] +id: GO:0090727 +name: positive regulation of brood size +namespace: biological_process +def: "Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." [GOC:rz] +is_a: GO:0060378 ! regulation of brood size +created_by: tb +creation_date: 2016-12-19T15:07:32Z + +[Term] +id: GO:0090728 +name: negative regulation of brood size +namespace: biological_process +def: "Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." [GOC:rz] +is_a: GO:0060378 ! regulation of brood size +created_by: tb +creation_date: 2016-12-19T15:07:32Z + +[Term] +id: GO:0090729 +name: toxin activity +namespace: molecular_function +alt_id: GO:0050827 +def: "Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom." [GOC:pt] +synonym: "toxin receptor binding" EXACT [] +xref: Wikipedia:Toxin +is_a: GO:0003674 ! molecular_function +relationship: part_of GO:0035821 ! modulation of process of other organism +created_by: tb +creation_date: 2016-12-19T15:23:27Z + +[Term] +id: GO:0090730 +name: Las1 complex +namespace: cellular_component +def: "A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448)." [GOC:vw, PMID:26638174] +synonym: "Las1-Grc3-Rat1-Rai1" NARROW [GOC:vw] +is_a: GO:1902555 ! endoribonuclease complex +is_a: GO:1902911 ! protein kinase complex +is_a: GO:1905354 ! exoribonuclease complex +relationship: part_of GO:0005829 ! cytosol +created_by: tb +creation_date: 2017-01-05T16:51:46Z + +[Term] +id: GO:0090731 +name: cellular response to very-low-density lipoprotein particle stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus." [GOC:aruk, GOC:bc] +synonym: "cellular response to VLDL particle stimulus" EXACT [] +is_a: GO:0055094 ! response to lipoprotein particle +is_a: GO:0071402 ! cellular response to lipoprotein particle stimulus +created_by: tb +creation_date: 2017-01-31T17:10:08Z + +[Term] +id: GO:0090732 +name: cofilin-actin rod +namespace: cellular_component +def: "A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers." [GOC:sl, PMID:22573689, PMID:24760020] +is_a: GO:0031002 ! actin rod +created_by: tb +creation_date: 2017-01-31T17:44:04Z + +[Term] +id: GO:0090733 +name: tenascin complex +namespace: cellular_component +def: "A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R." [GOC:bhm, PMID:11731446, PMID:12845616, PMID:17909022, PMID:23658023] +comment: An example is Tenascin-N (Q9UQP3) in PMID:17909022 (IDA). +synonym: "Tenascin-C" NARROW [] +synonym: "Tenascin-N" NARROW [] +synonym: "Tenascin-R" NARROW [] +synonym: "Tenascin-W" NARROW [] +synonym: "Tenascin-X" NARROW [] +xref: IntAct:EBI-11789587 +xref: IntAct:EBI-13640819 +is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: tb +creation_date: 2017-02-01T16:29:55Z + +[Term] +id: GO:0090734 +name: site of DNA damage +namespace: cellular_component +def: "A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix." [GOC:pg] +xref: Wikipedia:DNA_repair +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005694 ! chromosome +created_by: tb +creation_date: 2017-02-03T17:24:08Z + +[Term] +id: GO:0090735 +name: DNA repair complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex." [GOC:pg, PMID:27113759, PMID:27233470] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: tb +creation_date: 2017-02-06T16:42:27Z + +[Term] +id: GO:0090736 +name: MATH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a meprin and TRAF homology (MATH) domain." [InterPro:IPR002083, PMID:22621901] +is_a: GO:0019904 ! protein domain specific binding +created_by: tb +creation_date: 2017-02-06T17:08:28Z + +[Term] +id: GO:0090737 +name: telomere maintenance via telomere trimming +namespace: biological_process +def: "A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:27918544] +is_a: GO:0000723 ! telomere maintenance +created_by: tb +creation_date: 2017-02-07T16:51:24Z + +[Term] +id: GO:0090740 +name: integral component of pigment granule membrane +namespace: cellular_component +def: "The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [PMID:11294610] +is_a: GO:0031301 ! integral component of organelle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0090741 ! pigment granule membrane +relationship: part_of GO:0090741 ! pigment granule membrane +created_by: tb +creation_date: 2017-05-16T17:48:35Z + +[Term] +id: GO:0090741 +name: pigment granule membrane +namespace: cellular_component +def: "Any membrane that is part of a pigment granule." [PMID:11294610] +is_a: GO:0098588 ! bounding membrane of organelle +created_by: tb +creation_date: 2017-05-16T22:33:39Z + +[Term] +id: GO:0093001 +name: glycolysis from storage polysaccharide through glucose-1-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH." [GOC:dph, GOC:glycolysis] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0061622 ! glycolytic process through glucose-1-phosphate + +[Term] +id: GO:0093002 +name: response to nematicide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes." [GOC:kvm, PMID:22301316] +synonym: "response to antihelmintic" EXACT [GOC:kvm] +synonym: "response to nematocide" EXACT [GOC:kvm] +is_a: GO:0009636 ! response to toxic substance + +[Term] +id: GO:0095500 +name: acetylcholine receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "acetylcholine receptor signalling pathway" EXACT [] +is_a: GO:0098926 ! postsynaptic signal transduction +relationship: part_of GO:1905145 ! cellular response to acetylcholine + +[Term] +id: GO:0097001 +name: ceramide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any ceramide, a class of lipids that is composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes." [GOC:sart] +is_a: GO:0033218 ! amide binding +is_a: GO:0046625 ! sphingolipid binding +created_by: pr +creation_date: 2011-03-09T11:34:09Z + +[Term] +id: GO:0097002 +name: mitochondrial inner boundary membrane +namespace: cellular_component +def: "The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane." [GOC:mcc, PMID:16054341, PMID:19019989] +synonym: "inner bounding mitochondrial membrane" EXACT [NIF_Subcellular:sao18461326] +xref: NIF_Subcellular:sao18461326 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005743 ! mitochondrial inner membrane +created_by: pr +creation_date: 2011-03-10T04:11:50Z + +[Term] +id: GO:0097003 +name: adipokinetic hormone receptor activity +namespace: molecular_function +def: "Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis." [GOC:sart, PMID:11904407] +synonym: "AKH receptor activity" EXACT [] +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: has_part GO:0055100 ! adiponectin binding +relationship: has_part GO:0097004 ! adipokinetic hormone binding +created_by: pr +creation_date: 2011-03-14T10:24:08Z + +[Term] +id: GO:0097004 +name: adipokinetic hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis." [GOC:sart, PMID:11904407] +synonym: "AKH binding" EXACT [] +is_a: GO:0017046 ! peptide hormone binding +created_by: pr +creation_date: 2011-03-14T12:50:02Z + +[Term] +id: GO:0097005 +name: adipokinetic hormone receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis." [GOC:sart, PMID:11904407] +synonym: "AKH receptor binding" EXACT [] +is_a: GO:0051428 ! peptide hormone receptor binding +created_by: pr +creation_date: 2011-03-14T12:58:19Z + +[Term] +id: GO:0097006 +name: regulation of plasma lipoprotein particle levels +namespace: biological_process +def: "Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism." [GOC:BHF] +synonym: "plasma lipoprotein particle homeostasis" NARROW [] +is_a: GO:0050789 ! regulation of biological process +created_by: pr +creation_date: 2011-03-15T09:52:53Z + +[Term] +id: GO:0097007 +name: 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone." [GOC:kad, MetaCyc:RXN-8620, PMID:21088219] +synonym: "4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity" EXACT [] +synonym: "TMTT synthase activity" EXACT [] +xref: MetaCyc:RXN-8620 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: pr +creation_date: 2011-03-16T04:37:20Z + +[Term] +id: GO:0097008 +name: (3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone." [GOC:kad, MetaCyc:RXN-8619, PMID:21088219] +synonym: "(3E)-4,8-dimethylnona-1,3,7-triene synthase activity" EXACT [] +synonym: "DNMT synthase activity" RELATED [] +xref: MetaCyc:RXN-8619 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: pr +creation_date: 2011-03-17T10:38:01Z + +[Term] +id: GO:0097009 +name: energy homeostasis +namespace: biological_process +alt_id: GO:2000505 +alt_id: GO:2000506 +alt_id: GO:2000507 +def: "Any process involved in the balance between food intake (energy input) and energy expenditure." [GOC:yaf, PMID:15919751] +synonym: "negative regulation of energy homeostasis" RELATED [] +synonym: "positive regulation of energy homeostasis" RELATED [] +synonym: "regulation of energy homeostasis" RELATED [] +is_a: GO:0048871 ! multicellular organismal homeostasis +created_by: pr +creation_date: 2011-03-21T10:52:44Z + +[Term] +id: GO:0097010 +name: eukaryotic translation initiation factor 4F complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex." [GOC:BHF, GOC:ebc, PMID:18337562] +synonym: "eIF-4F assembly" EXACT [GOC:pr] +synonym: "eIF4F assembly" EXACT [GOC:pr] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: pr +creation_date: 2011-03-21T04:19:26Z + +[Term] +id: GO:0097011 +name: cellular response to granulocyte macrophage colony-stimulating factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus." [GOC:BHF, GOC:ebc, PMID:7901744] +synonym: "cellular response to GM-CSF stimulus" EXACT [] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:0097012 ! response to granulocyte macrophage colony-stimulating factor +created_by: pr +creation_date: 2011-03-21T05:25:06Z + +[Term] +id: GO:0097012 +name: response to granulocyte macrophage colony-stimulating factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus." [GOC:pr] +synonym: "response to GM-CSF" EXACT [] +synonym: "response to granulocyte macrophage colony-stimulating factor stimulus" EXACT [GOC:dos] +is_a: GO:0034097 ! response to cytokine +created_by: pr +creation_date: 2011-03-22T01:12:15Z + +[Term] +id: GO:0097013 +name: phagocytic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a phagocytic vesicle." [GOC:rs] +is_a: GO:0071682 ! endocytic vesicle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0045335 ! phagocytic vesicle +relationship: part_of GO:0045335 ! phagocytic vesicle +created_by: pr +creation_date: 2011-03-22T01:44:47Z + +[Term] +id: GO:0097014 +name: ciliary plasm +namespace: cellular_component +def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm". +synonym: "cilial cytoplasm" RELATED [] +synonym: "ciliary cytoplasm" RELATED [] +synonym: "cilium cytoplasm" RELATED [] +synonym: "cilium plasm" EXACT [] +synonym: "microtubule-based flagellar cytoplasm" RELATED [] +synonym: "microtubule-based flagellar matrix" NARROW [] +synonym: "microtubule-based flagellum cytoplasm" RELATED [] +synonym: "microtubule-based flagellum matrix" NARROW [] +is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0005929 ! cilium +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2011-03-23T01:52:31Z + +[Term] +id: GO:0097015 +name: obsolete bacterial-type flagellar cytoplasm +namespace: cellular_component +def: "OBSOLETE. All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum." [GOC:BHF] +comment: The reason for obsoletion is that this term describes a cellular component that does not exist. +synonym: "bacterial-type flagellum cytoplasm" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2011-03-23T01:59:44Z + +[Term] +id: GO:0097016 +name: L27 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner." [GOC:BHF, PMID:15241471, PMID:17237226, Prosite:PDOC51022] +is_a: GO:0019904 ! protein domain specific binding +created_by: pr +creation_date: 2011-03-23T02:17:51Z + +[Term] +id: GO:0097017 +name: renal protein absorption +namespace: biological_process +def: "A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)." [GOC:yaf, PMID:18431508] +is_a: GO:0070293 ! renal absorption +created_by: pr +creation_date: 2011-03-23T03:13:04Z + +[Term] +id: GO:0097018 +name: renal albumin absorption +namespace: biological_process +def: "A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron." [GOC:yaf, PMID:18431508] +is_a: GO:0097017 ! renal protein absorption +created_by: pr +creation_date: 2011-03-23T03:15:04Z + +[Term] +id: GO:0097019 +name: neurotransmitter receptor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors." [GOC:kmv] +synonym: "neurotransmitter receptor breakdown" EXACT [] +synonym: "neurotransmitter receptor catabolism" EXACT [] +synonym: "neurotransmitter receptor degradation" EXACT [] +is_a: GO:0032801 ! receptor catabolic process +is_a: GO:0045213 ! neurotransmitter receptor metabolic process +created_by: pr +creation_date: 2011-03-23T04:16:11Z + +[Term] +id: GO:0097020 +name: COPII adaptor activity +namespace: molecular_function +def: "Bringing together a cargo protein with the COPII coat complex component to allow its uptake by the COPII vesicle." [GOC:rb, PMID:16957051, PMID:20236934] +is_a: GO:0140312 ! cargo adaptor activity +created_by: pr +creation_date: 2011-03-24T04:19:55Z + +[Term] +id: GO:0097021 +name: lymphocyte migration into lymphoid organs +namespace: biological_process +def: "The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen." [GOC:BHF, GOC:pr, PMID:18379575] +synonym: "lymphocyte homing" NARROW [] +is_a: GO:0072676 ! lymphocyte migration +created_by: pr +creation_date: 2011-03-29T04:26:08Z + +[Term] +id: GO:0097022 +name: lymphocyte migration into lymph node +namespace: biological_process +def: "The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen." [GOC:BHF, GOC:pr, PMID:18379575] +synonym: "lymphocyte homing" EXACT [] +is_a: GO:0097021 ! lymphocyte migration into lymphoid organs +created_by: pr +creation_date: 2011-03-29T04:29:27Z + +[Term] +id: GO:0097023 +name: fructose 6-phosphate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate." [GOC:imk, PMID:11120740, PMID:21290439] +xref: RHEA:28002 +is_a: GO:0016832 ! aldehyde-lyase activity +created_by: pr +creation_date: 2011-03-29T04:54:05Z + +[Term] +id: GO:0097025 +name: MPP7-DLG1-LIN7 complex +namespace: cellular_component +def: "A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions." [GOC:BHF, PMID:17237226] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005912 ! adherens junction +created_by: pr +creation_date: 2011-03-30T05:03:33Z + +[Term] +id: GO:0097026 +name: dendritic cell dendrite assembly +namespace: biological_process +def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351] +comment: Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals. +synonym: "dendritic extension" BROAD [] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +created_by: pr +creation_date: 2011-03-31T04:52:53Z + +[Term] +id: GO:0097027 +name: ubiquitin-protein transferase activator activity +namespace: molecular_function +def: "Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein." [GOC:rb, PMID:18321851] +is_a: GO:0055106 ! ubiquitin-protein transferase regulator activity +relationship: positively_regulates GO:0004842 ! ubiquitin-protein transferase activity +created_by: pr +creation_date: 2011-03-31T05:19:23Z + +[Term] +id: GO:0097028 +name: dendritic cell differentiation +namespace: biological_process +def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr] +comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. +is_a: GO:0002521 ! leukocyte differentiation +created_by: pr +creation_date: 2011-04-01T10:08:42Z + +[Term] +id: GO:0097029 +name: mature conventional dendritic cell differentiation +namespace: biological_process +def: "The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells." [GOC:BHF, http://www.rndsystems.com/mini_review_detail_objectname_MR02_DendriticCellMat.aspx, PMID:15845453] +comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. +is_a: GO:0002573 ! myeloid leukocyte differentiation +is_a: GO:0097028 ! dendritic cell differentiation +created_by: pr +creation_date: 2011-04-01T10:10:22Z + +[Term] +id: GO:0097030 +name: CENP-A containing nucleosome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3)." [GOC:jp, PMID:21412236] +synonym: "centromere-specific nucleosome binding" RELATED [GOC:vw] +synonym: "centromeric nucleosome binding" RELATED [] +is_a: GO:0031491 ! nucleosome binding +created_by: pr +creation_date: 2011-04-01T03:19:35Z + +[Term] +id: GO:0097031 +name: obsolete mitochondrial respiratory chain complex I biogenesis +namespace: biological_process +def: "OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:pr] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true +created_by: pr +creation_date: 2011-04-05T02:53:14Z + +[Term] +id: GO:0097032 +name: obsolete mitochondrial respiratory chain complex II biogenesis +namespace: biological_process +def: "OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:pr] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true +created_by: pr +creation_date: 2011-04-05T02:57:33Z + +[Term] +id: GO:0097033 +name: obsolete mitochondrial respiratory chain complex III biogenesis +namespace: biological_process +def: "OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:mcc] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +synonym: "mitochondrial cytochrome bc(1) complex biogenesis" EXACT [GOC:pr] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true +created_by: pr +creation_date: 2011-04-05T03:00:31Z + +[Term] +id: GO:0097034 +name: obsolete mitochondrial respiratory chain complex IV biogenesis +namespace: biological_process +def: "OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together." [GOC:mcc] +comment: The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation. +synonym: "mitochondrial cytochrome c oxidase complex biogenesis" EXACT [GOC:pr] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15173 xsd:anyURI +is_obsolete: true +created_by: pr +creation_date: 2011-04-05T03:02:54Z + +[Term] +id: GO:0097035 +name: regulation of membrane lipid distribution +namespace: biological_process +def: "Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane." [GOC:mah, PMID:18441123, PMID:20823909] +is_a: GO:0061024 ! membrane organization +is_a: GO:0065008 ! regulation of biological quality +created_by: pr +creation_date: 2011-04-08T02:01:19Z + +[Term] +id: GO:0097036 +name: regulation of plasma membrane sterol distribution +namespace: biological_process +def: "Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane." [GOC:mah, PMID:18441123, PMID:20823909] +is_a: GO:0007009 ! plasma membrane organization +is_a: GO:0097035 ! regulation of membrane lipid distribution +created_by: pr +creation_date: 2011-04-08T02:08:08Z + +[Term] +id: GO:0097037 +name: heme export +namespace: biological_process +def: "The directed movement of heme out of a cell or organelle." [GOC:lf, PMID:15369674, PMID:20610401] +is_a: GO:0015886 ! heme transport +created_by: pr +creation_date: 2011-04-11T10:39:22Z + +[Term] +id: GO:0097038 +name: perinuclear endoplasmic reticulum +namespace: cellular_component +def: "The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes." [GOC:bf, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] +synonym: "perinuclear ER" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0048471 ! perinuclear region of cytoplasm +created_by: pr +creation_date: 2011-04-12T10:51:05Z + +[Term] +id: GO:0097039 +name: protein linear polyubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein." [GOC:jsg, GOC:sp, PMID:21455173, PMID:21455180, PMID:21455181] +synonym: "M1 linkage" NARROW [] +is_a: GO:0000209 ! protein polyubiquitination +created_by: pr +creation_date: 2011-04-13T01:52:51Z + +[Term] +id: GO:0097040 +name: phthiocerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents." [GOC:dph, GOC:ecd, PMID:9201977] +synonym: "phthiocerol anabolism" EXACT [] +synonym: "phthiocerol biosynthesis" EXACT [] +synonym: "phthiocerol formation" EXACT [] +synonym: "phthiocerol synthesis" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0042845 ! glycol biosynthetic process +created_by: pr +creation_date: 2011-04-15T01:18:17Z + +[Term] +id: GO:0097041 +name: phenolic phthiocerol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position." [GOC:dph, GOC:ecd, PMID:9201977] +synonym: "phenolic phthiocerol anabolism" EXACT [] +synonym: "phenolic phthiocerol biosynthesis" EXACT [] +synonym: "phenolic phthiocerol formation" EXACT [] +synonym: "phenolic phthiocerol synthesis" EXACT [] +synonym: "phenolphthiocerol biosynthesis" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +created_by: pr +creation_date: 2011-04-15T01:25:59Z + +[Term] +id: GO:0097042 +name: extrinsic component of fungal-type vacuolar membrane +namespace: cellular_component +def: "The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:jh, PMID:21454883] +synonym: "extrinsic to fungal-type vacuolar membrane" NARROW [] +is_a: GO:0000306 ! extrinsic component of vacuolar membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0000329 ! fungal-type vacuole membrane +relationship: part_of GO:0000329 ! fungal-type vacuole membrane +created_by: pr +creation_date: 2011-04-19T03:42:39Z + +[Term] +id: GO:0097043 +name: histone H3-K56 acetylation +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone." [GOC:bf, GOC:pr] +is_a: GO:0043966 ! histone H3 acetylation +created_by: pr +creation_date: 2011-04-19T05:18:29Z + +[Term] +id: GO:0097044 +name: histone H3-K56 acetylation in response to DNA damage +namespace: biological_process +def: "The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell." [GOC:pr, GOC:vw, PMID:18344406] +is_a: GO:0097043 ! histone H3-K56 acetylation +relationship: part_of GO:0006974 ! cellular response to DNA damage stimulus +created_by: pr +creation_date: 2011-04-19T05:22:54Z + +[Term] +id: GO:0097045 +name: phosphatidylserine exposure on blood platelet +namespace: biological_process +def: "A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system." [GOC:bf, GOC:lf, GOC:pr, PMID:21107324] +is_a: GO:0017121 ! plasma membrane phospholipid scrambling +is_a: GO:0030194 ! positive regulation of blood coagulation +created_by: pr +creation_date: 2011-04-20T12:54:35Z + +[Term] +id: GO:0097046 +name: replication fork progression beyond termination site +namespace: biological_process +def: "Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks." [GOC:bf, GOC:mcc, GOC:pr, PMID:20797631] +is_a: GO:2000621 ! regulation of DNA replication termination +created_by: pr +creation_date: 2011-05-03T03:34:01Z + +[Term] +id: GO:0097047 +name: DNA replication termination region +namespace: cellular_component +def: "A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks." [GOC:mcc, GOC:pr, PMID:20797631] +synonym: "TER" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005694 ! chromosome +created_by: pr +creation_date: 2011-05-03T03:38:40Z + +[Term] +id: GO:0097048 +name: dendritic cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845] +synonym: "dendritic cell apoptosis" NARROW [] +is_a: GO:0071887 ! leukocyte apoptotic process +created_by: pr +creation_date: 2011-05-04T02:18:59Z + +[Term] +id: GO:0097049 +name: motor neuron apoptotic process +namespace: biological_process +def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086] +synonym: "motoneuron apoptosis" EXACT [] +synonym: "motor neuron apoptosis" NARROW [] +is_a: GO:0051402 ! neuron apoptotic process +created_by: pr +creation_date: 2011-05-04T02:21:43Z + +[Term] +id: GO:0097050 +name: type B pancreatic cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305] +synonym: "pancreatic B cell apoptosis" EXACT [] +synonym: "pancreatic beta cell apoptosis" EXACT [] +synonym: "type B pancreatic cell apoptosis" NARROW [] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: pr +creation_date: 2011-05-04T02:24:38Z + +[Term] +id: GO:0097051 +name: establishment of protein localization to endoplasmic reticulum membrane +namespace: biological_process +def: "The directed movement of a protein to a specific location in the endoplasmic reticulum membrane." [GOC:rb, PMID:9388185] +synonym: "establishment of protein localisation in endoplasmic reticulum membrane" EXACT [GOC:mah] +synonym: "establishment of protein localization in endoplasmic reticulum membrane" EXACT [] +is_a: GO:0072599 ! establishment of protein localization to endoplasmic reticulum +is_a: GO:0090150 ! establishment of protein localization to membrane +created_by: pr +creation_date: 2011-05-04T05:55:26Z + +[Term] +id: GO:0097052 +name: L-kynurenine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)." [GOC:yaf] +synonym: "L-kynurenine metabolism" EXACT [] +is_a: GO:0070189 ! kynurenine metabolic process +created_by: pr +creation_date: 2011-05-24T03:28:44Z + +[Term] +id: GO:0097053 +name: L-kynurenine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)." [GOC:yaf] +synonym: "L-kynurenine breakdown" EXACT [] +synonym: "L-kynurenine catabolism" EXACT [] +synonym: "L-kynurenine degradation" EXACT [] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0097052 ! L-kynurenine metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +created_by: pr +creation_date: 2011-05-24T03:30:58Z + +[Term] +id: GO:0097054 +name: L-glutamate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid." [GOC:yaf] +synonym: "L-glutamate anabolism" EXACT [] +synonym: "L-glutamate biosynthesis" EXACT [] +synonym: "L-glutamate formation" EXACT [] +synonym: "L-glutamate synthesis" EXACT [] +is_a: GO:0006537 ! glutamate biosynthetic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +created_by: pr +creation_date: 2011-05-24T04:30:38Z + +[Term] +id: GO:0097055 +name: agmatine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase." [GOC:pr, GOC:yaf] +synonym: "agmatine anabolism" EXACT [] +synonym: "agmatine biosynthesis" EXACT [] +synonym: "agmatine formation" EXACT [] +synonym: "agmatine synthesis" EXACT [] +is_a: GO:1901162 ! primary amino compound biosynthetic process +created_by: pr +creation_date: 2011-05-25T03:56:17Z + +[Term] +id: GO:0097056 +name: selenocysteinyl-tRNA(Sec) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine." [GOC:yaf, PMID:15317934, UniPathway:UPA00906] +synonym: "selenocysteinyl-tRNA(Sec) anabolism" EXACT [] +synonym: "selenocysteinyl-tRNA(Sec) biosynthesis" EXACT [] +synonym: "selenocysteinyl-tRNA(Sec) formation" EXACT [] +synonym: "selenocysteinyl-tRNA(Sec) synthesis" EXACT [] +is_a: GO:0006399 ! tRNA metabolic process +is_a: GO:0032774 ! RNA biosynthetic process +created_by: pr +creation_date: 2011-05-25T05:33:19Z + +[Term] +id: GO:0097057 +name: TRAF2-GSTP1 complex +namespace: cellular_component +def: "A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses." [GOC:BHF, PMID:16636664] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2011-05-26T10:35:45Z + +[Term] +id: GO:0097058 +name: CRLF-CLCF1 complex +namespace: cellular_component +def: "A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex." [GOC:BHF, PMID:10966616] +synonym: "CLF-CLC complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: pr +creation_date: 2011-05-26T10:37:55Z + +[Term] +id: GO:0097059 +name: CNTFR-CLCF1 complex +namespace: cellular_component +def: "A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space." [GOC:BHF, PMID:11285233] +synonym: "sCNTFR-CLC complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: pr +creation_date: 2011-05-26T10:43:22Z + +[Term] +id: GO:0097060 +name: synaptic membrane +namespace: cellular_component +def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104] +subset: goslim_synapse +is_a: GO:0098590 ! plasma membrane region +intersection_of: GO:0098590 ! plasma membrane region +intersection_of: part_of GO:0045202 ! synapse +relationship: part_of GO:0045202 ! synapse +created_by: pr +creation_date: 2011-06-07T11:22:09Z + +[Term] +id: GO:0097061 +name: dendritic spine organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission." [GOC:BHF, PMID:20410104] +synonym: "dendritic spine organisation" EXACT [] +is_a: GO:0099173 ! postsynapse organization +is_a: GO:0106027 ! neuron projection organization +created_by: pr +creation_date: 2011-06-07T11:26:53Z + +[Term] +id: GO:0097062 +name: dendritic spine maintenance +namespace: biological_process +def: "The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission." [GOC:BHF, PMID:20410104] +is_a: GO:0043954 ! cellular component maintenance +is_a: GO:0097061 ! dendritic spine organization +created_by: pr +creation_date: 2011-06-07T11:29:03Z + +[Term] +id: GO:0097063 +name: cadmium ion sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++)." [GOC:rs, PMID:19456862] +is_a: GO:0046870 ! cadmium ion binding +is_a: GO:0140299 ! small molecule sensor activity +created_by: pr +creation_date: 2011-06-08T09:46:14Z + +[Term] +id: GO:0097064 +name: ncRNA export from nucleus +namespace: biological_process +def: "The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm." [GOC:dgf, PMID:11352936] +synonym: "non-coding RNA export from nucleus" EXACT [GOC:pr] +is_a: GO:0006405 ! RNA export from nucleus +created_by: pr +creation_date: 2011-06-08T12:34:34Z + +[Term] +id: GO:0097065 +name: anterior head development +namespace: biological_process +def: "The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure." [GOC:yaf, PMID:14695376, PMID:15857913] +is_a: GO:0060322 ! head development +created_by: pr +creation_date: 2011-06-08T12:38:11Z + +[Term] +id: GO:0097066 +name: response to thyroid hormone +namespace: biological_process +def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus." [GOC:sjw, PMID:9916872] +synonym: "response to thyroid hormone stimulus" EXACT [GOC:dos] +is_a: GO:0009725 ! response to hormone +created_by: pr +creation_date: 2011-06-14T05:01:18Z + +[Term] +id: GO:0097067 +name: cellular response to thyroid hormone stimulus +namespace: biological_process +def: "A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus." [GOC:sjw, PMID:9916872] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0097066 ! response to thyroid hormone +created_by: pr +creation_date: 2011-06-14T05:02:47Z + +[Term] +id: GO:0097068 +name: response to thyroxine +namespace: biological_process +def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus." [GOC:sjw, PMID:9916872] +synonym: "response to T4" EXACT [Wikipedia:Thyroxine] +synonym: "response to T4 stimulus" EXACT [Wikipedia:Thyroxine] +synonym: "response to thyroxine stimulus" EXACT [GOC:dos] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +is_a: GO:0097066 ! response to thyroid hormone +is_a: GO:1904386 ! response to L-phenylalanine derivative +created_by: pr +creation_date: 2011-06-14T05:05:07Z + +[Term] +id: GO:0097069 +name: cellular response to thyroxine stimulus +namespace: biological_process +def: "A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus." [GOC:sjw, PMID:9916872] +synonym: "cellular response to T4 stimulus" EXACT [Wikipedia:Thyroxine] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097067 ! cellular response to thyroid hormone stimulus +is_a: GO:0097068 ! response to thyroxine +is_a: GO:1904387 ! cellular response to L-phenylalanine derivative +created_by: pr +creation_date: 2011-06-14T05:06:48Z + +[Term] +id: GO:0097070 +name: ductus arteriosus closure +namespace: biological_process +def: "The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs." [GOC:hw] +is_a: GO:0048844 ! artery morphogenesis +created_by: pr +creation_date: 2011-06-15T04:00:46Z + +[Term] +id: GO:0097071 +name: interferon regulatory factor complex +namespace: cellular_component +def: "A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit." [GOC:cna, PMID:20043992] +synonym: "IRF complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2011-06-15T04:22:30Z + +[Term] +id: GO:0097072 +name: interferon regulatory factor 3 complex +namespace: cellular_component +def: "An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3." [GOC:cna, PMID:12855817, PMID:14556004, Reactome:R-HSA-166272] +synonym: "IRF3:IRF3 complex" EXACT [] +is_a: GO:0097071 ! interferon regulatory factor complex +created_by: pr +creation_date: 2011-06-15T04:26:10Z + +[Term] +id: GO:0097073 +name: interferon regulatory factor 5 complex +namespace: cellular_component +def: "An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5." [GOC:cna, PMID:12138184, PMID:16751392] +synonym: "IRF5:IRF5 complex" EXACT [] +is_a: GO:0097071 ! interferon regulatory factor complex +created_by: pr +creation_date: 2011-06-15T04:28:57Z + +[Term] +id: GO:0097074 +name: interferon regulatory factor 7 complex +namespace: cellular_component +def: "An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7." [GOC:cna, PMID:18068231, Reactome:R-HSA-450344] +synonym: "IRF7:IRF7 complex" EXACT [] +is_a: GO:0097071 ! interferon regulatory factor complex +created_by: pr +creation_date: 2011-06-15T04:31:04Z + +[Term] +id: GO:0097075 +name: interferon regulatory factor 3-interferon regulatory factor 7 complex +namespace: cellular_component +def: "An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7." [GOC:cna, PMID:18068231, Reactome:R-HSA-1027367] +synonym: "IRF3:IRF7 complex" EXACT [] +is_a: GO:0097071 ! interferon regulatory factor complex +created_by: pr +creation_date: 2011-06-15T04:33:36Z + +[Term] +id: GO:0097076 +name: transforming growth factor beta activated kinase 1 complex +namespace: cellular_component +def: "A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits)." [GOC:cna, PMID:16410796, PMID:17496917, PMID:18021073] +synonym: "TAK1 kinase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2011-06-15T04:55:32Z + +[Term] +id: GO:0097077 +name: copper ion sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+)." [GOC:rs, PMID:19928961] +is_a: GO:0005507 ! copper ion binding +is_a: GO:0140299 ! small molecule sensor activity +created_by: pr +creation_date: 2011-06-17T09:57:11Z + +[Term] +id: GO:0097078 +name: FAL1-SGD1 complex +namespace: cellular_component +def: "A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits." [GOC:rb, PMID:21576267] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2011-06-17T09:59:10Z + +[Term] +id: GO:0097079 +name: selenite:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in)." [GOC:mcc, PMID:20861301] +synonym: "selenite:H+ symporter activity" EXACT [] +synonym: "selenite:hydrogen symporter activity" EXACT [] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +created_by: pr +creation_date: 2011-06-17T10:01:11Z + +[Term] +id: GO:0097080 +name: plasma membrane selenite transport +namespace: biological_process +def: "The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane." [GOC:mcc, PMID:20861301] +synonym: "plasma membrane hydrogenselenite transport" EXACT [] +is_a: GO:0098656 ! anion transmembrane transport +created_by: pr +creation_date: 2011-06-17T10:03:55Z + +[Term] +id: GO:0097081 +name: vascular smooth muscle cell fate commitment +namespace: biological_process +def: "The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] +is_a: GO:0042693 ! muscle cell fate commitment +relationship: part_of GO:0035886 ! vascular smooth muscle cell differentiation +created_by: pr +creation_date: 2011-06-20T03:51:52Z + +[Term] +id: GO:0097082 +name: vascular smooth muscle cell fate specification +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] +is_a: GO:0042694 ! muscle cell fate specification +relationship: part_of GO:0097081 ! vascular smooth muscle cell fate commitment +created_by: pr +creation_date: 2011-06-20T03:56:21Z + +[Term] +id: GO:0097083 +name: vascular smooth muscle cell fate determination +namespace: biological_process +def: "The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] +is_a: GO:0007521 ! muscle cell fate determination +relationship: part_of GO:0097081 ! vascular smooth muscle cell fate commitment +created_by: pr +creation_date: 2011-06-20T04:00:28Z + +[Term] +id: GO:0097084 +name: vascular smooth muscle cell development +namespace: biological_process +def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] +is_a: GO:0055001 ! muscle cell development +relationship: part_of GO:0035886 ! vascular smooth muscle cell differentiation +created_by: pr +creation_date: 2011-06-20T04:03:08Z + +[Term] +id: GO:0097085 +name: interferon regulatory factor 3-interferon regulatory factor 5 complex +namespace: cellular_component +def: "An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5." [GOC:cna, PMID:12138184] +synonym: "IRF3:IRF5 complex" EXACT [] +is_a: GO:0097071 ! interferon regulatory factor complex +created_by: pr +creation_date: 2011-06-21T06:30:30Z + +[Term] +id: GO:0097086 +name: amniotic stem cell differentiation +namespace: biological_process +def: "The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone." [CL:0002639, GOC:yaf, PMID:20942606, Wikipedia:Amniotic_stem_cells] +is_a: GO:0072497 ! mesenchymal stem cell differentiation +created_by: pr +creation_date: 2011-06-22T11:17:52Z + +[Term] +id: GO:0097087 +name: interleukin-17A production +namespace: biological_process +def: "The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv, PR:000001138, Wikipedia:Interleukin_17] +synonym: "IL-17A production" EXACT [] +is_a: GO:0032620 ! interleukin-17 production +created_by: pr +creation_date: 2011-06-23T11:31:10Z + +[Term] +id: GO:0097088 +name: interleukin-17F production +namespace: biological_process +def: "The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv, PR:000001142, Wikipedia:Interleukin_17] +synonym: "IL-17F production" EXACT [] +is_a: GO:0032620 ! interleukin-17 production +created_by: pr +creation_date: 2011-06-23T11:32:59Z + +[Term] +id: GO:0097089 +name: methyl-branched fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain." [GOC:rs, PMID:19933331] +synonym: "methyl-branched fatty acid metabolism" EXACT [] +is_a: GO:0006631 ! fatty acid metabolic process +created_by: pr +creation_date: 2011-07-01T01:06:15Z + +[Term] +id: GO:0097090 +name: presynaptic membrane organization +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction." [GOC:BHF, GOC:pr, GOC:sjp, PMID:19730411] +comment: Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron. +synonym: "pre-synaptic membrane organization" EXACT [] +synonym: "presynaptic membrane organisation" EXACT [] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0050808 ! synapse organization +created_by: pr +creation_date: 2011-07-04T01:45:30Z + +[Term] +id: GO:0097091 +name: synaptic vesicle clustering +namespace: biological_process +def: "The process that results in grouping synaptic vesicles in presynaptic structures." [GOC:ans, GOC:pr, PMID:19900895, PMID:7568108] +subset: goslim_synapse +is_a: GO:0097479 ! synaptic vesicle localization +relationship: part_of GO:0099504 ! synaptic vesicle cycle +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/163 xsd:anyURI +created_by: pr +creation_date: 2011-07-04T01:48:24Z + +[Term] +id: GO:0097092 +name: polyacyltrehalose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid." [GOC:rs, PMID:19729090] +synonym: "polyacyltrehalose metabolism" EXACT [] +is_a: GO:0006664 ! glycolipid metabolic process +created_by: pr +creation_date: 2011-07-05T01:58:28Z + +[Term] +id: GO:0097093 +name: polyacyltrehalose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid." [GOC:rs, PMID:19729090] +synonym: "polyacyltrehalose anabolism" EXACT [] +synonym: "polyacyltrehalose biosynthesis" EXACT [] +synonym: "polyacyltrehalose formation" EXACT [] +synonym: "polyacyltrehalose synthesis" EXACT [] +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:0097092 ! polyacyltrehalose metabolic process +created_by: pr +creation_date: 2011-07-05T02:01:08Z + +[Term] +id: GO:0097094 +name: craniofacial suture morphogenesis +namespace: biological_process +def: "The process in which any suture between cranial and/or facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0060349 ! bone morphogenesis +relationship: part_of GO:1904888 ! cranial skeletal system development +created_by: pr +creation_date: 2011-07-05T02:51:54Z + +[Term] +id: GO:0097095 +name: frontonasal suture morphogenesis +namespace: biological_process +def: "The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized." [GOC:pr, GOC:sl, PMID:12416537, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] +synonym: "nasofrontal suture morphogenesis" EXACT [] +is_a: GO:0097094 ! craniofacial suture morphogenesis +created_by: pr +creation_date: 2011-07-05T02:57:46Z + +[Term] +id: GO:0097096 +name: facial suture morphogenesis +namespace: biological_process +def: "The process in which any suture between facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] +is_a: GO:0097094 ! craniofacial suture morphogenesis +created_by: pr +creation_date: 2011-07-05T03:06:27Z + +[Term] +id: GO:0097097 +name: nasal suture morphogenesis +namespace: biological_process +def: "The process in which the nasal suture is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] +synonym: "internasal suture morphogenesis" EXACT [] +is_a: GO:0097096 ! facial suture morphogenesis +created_by: pr +creation_date: 2011-07-05T03:09:04Z + +[Term] +id: GO:0097098 +name: DNA/RNA hybrid annealing activity +namespace: molecular_function +def: "Facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops." [GOC:imk, PMID:21699496] +is_a: GO:0071667 ! DNA/RNA hybrid binding +is_a: GO:0097617 ! annealing activity +created_by: pr +creation_date: 2011-07-07T11:20:44Z + +[Term] +id: GO:0097099 +name: structural constituent of albumen +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo." [GOC:jj, Wikipedia:Albumen] +synonym: "structural constituent of egg white" EXACT [] +is_a: GO:0005198 ! structural molecule activity +created_by: pr +creation_date: 2011-07-07T02:12:51Z + +[Term] +id: GO:0097100 +name: supercoiled DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA." [GOC:pr, GOC:rph, PMID:20723754, PMID:21345933, Wikipedia:DNA_supercoil] +is_a: GO:0003690 ! double-stranded DNA binding +created_by: pr +creation_date: 2011-07-12T03:28:57Z + +[Term] +id: GO:0097101 +name: blood vessel endothelial cell fate specification +namespace: biological_process +def: "The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [CL:0002139, GOC:dgh, PMID:21521739] +is_a: GO:0060847 ! endothelial cell fate specification +relationship: part_of GO:0060846 ! blood vessel endothelial cell fate commitment +created_by: pr +creation_date: 2011-07-27T10:24:32Z + +[Term] +id: GO:0097102 +name: endothelial tip cell fate specification +namespace: biological_process +def: "The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels." [CL:0000704, GOC:dgh, PMID:21521739] +synonym: "angiogenic tip cell fate specification" EXACT [] +is_a: GO:0097101 ! blood vessel endothelial cell fate specification +relationship: part_of GO:0002040 ! sprouting angiogenesis +created_by: pr +creation_date: 2011-07-27T10:29:00Z + +[Term] +id: GO:0097103 +name: endothelial stalk cell fate specification +namespace: biological_process +def: "The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout." [CL:0002671, GOC:dgh, PMID:21521739] +synonym: "angiogenic stalk cell fate specification" EXACT [] +is_a: GO:0097101 ! blood vessel endothelial cell fate specification +relationship: part_of GO:0002040 ! sprouting angiogenesis +created_by: pr +creation_date: 2011-07-27T10:32:38Z + +[Term] +id: GO:0097104 +name: postsynaptic membrane assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)." [GOC:BHF, GOC:sjp, PMID:21424692] +subset: goslim_synapse +synonym: "post-synaptic membrane assembly" EXACT [] +is_a: GO:0001941 ! postsynaptic membrane organization +is_a: GO:0071709 ! membrane assembly +relationship: part_of GO:0099068 ! postsynapse assembly +created_by: pr +creation_date: 2011-07-27T01:26:49Z + +[Term] +id: GO:0097105 +name: presynaptic membrane assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction." [GOC:BHF, GOC:pr, GOC:sjp, PMID:15797875, PMID:18550748] +comment: Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron. +subset: goslim_synapse +synonym: "pre-synaptic membrane assembly" EXACT [] +is_a: GO:0071709 ! membrane assembly +is_a: GO:0097090 ! presynaptic membrane organization +relationship: part_of GO:0099054 ! presynapse assembly +created_by: pr +creation_date: 2011-07-27T01:30:45Z + +[Term] +id: GO:0097106 +name: postsynaptic density organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse." [GOC:BHF, GOC:sjp, PMID:21525273] +synonym: "post synaptic density organization" EXACT [] +synonym: "post-synaptic density organization" EXACT [] +synonym: "postsynaptic density organisation" EXACT [] +synonym: "PSD organization" EXACT [] +is_a: GO:0099084 ! postsynaptic specialization organization +created_by: pr +creation_date: 2011-07-27T05:17:12Z + +[Term] +id: GO:0097107 +name: postsynaptic density assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse." [GOC:BHF, GOC:sjp, PMID:21525273] +subset: goslim_synapse +synonym: "post synaptic density assembly" EXACT [] +synonym: "post-synaptic density assembly" EXACT [] +synonym: "PSD assembly" EXACT [] +is_a: GO:0097106 ! postsynaptic density organization +is_a: GO:0098698 ! postsynaptic specialization assembly +relationship: part_of GO:1904861 ! excitatory synapse assembly +created_by: pr +creation_date: 2011-07-27T05:21:39Z + +[Term] +id: GO:0097108 +name: hedgehog family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development." [GOC:BHF, GOC:pr, PMID:10050855] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2011-07-28T10:06:45Z + +[Term] +id: GO:0097109 +name: neuroligin family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation." [GOC:BHF, GOC:pr, GOC:sjp, PMID:21424692] +is_a: GO:0005102 ! signaling receptor binding +created_by: pr +creation_date: 2011-07-28T05:15:22Z + +[Term] +id: GO:0097110 +name: scaffold protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes." [GOC:BHF, GOC:sjp, PMID:10433269, Wikipedia:Scaffold_protein] +is_a: GO:0005515 ! protein binding +created_by: pr +creation_date: 2011-07-28T05:16:53Z + +[Term] +id: GO:0097111 +name: endoplasmic reticulum-Golgi intermediate compartment organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment." [GOC:br, PMID:18287528] +synonym: "endoplasmic reticulum-Golgi intermediate compartment organisation" EXACT [] +synonym: "endoplasmic reticulum-Golgi intermediate compartment organization and biogenesis" RELATED [] +synonym: "ER-Golgi intermediate compartment organization" EXACT [] +synonym: "ERGIC organization" EXACT [] +is_a: GO:0006996 ! organelle organization +created_by: pr +creation_date: 2011-07-29T04:45:54Z + +[Term] +id: GO:0097112 +name: gamma-aminobutyric acid receptor clustering +namespace: biological_process +def: "The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane." [GOC:BHF, GOC:sjp, PMID:15620359] +synonym: "GABA receptor clustering" EXACT [] +is_a: GO:0072578 ! neurotransmitter-gated ion channel clustering +relationship: part_of GO:0001941 ! postsynaptic membrane organization +created_by: pr +creation_date: 2011-07-31T05:21:08Z + +[Term] +id: GO:0097113 +name: AMPA glutamate receptor clustering +namespace: biological_process +def: "The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane." [GOC:BHF, GOC:pr, GOC:sjp, PMID:12796785] +synonym: "alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [] +synonym: "AMPA receptor clustering" EXACT [] +is_a: GO:0097688 ! glutamate receptor clustering +relationship: part_of GO:0001941 ! postsynaptic membrane organization +created_by: pr +creation_date: 2011-07-31T05:25:53Z + +[Term] +id: GO:0097114 +name: NMDA glutamate receptor clustering +namespace: biological_process +def: "The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane." [GOC:BHF, GOC:sjp, PMID:15620359] +synonym: "N-methyl-D-aspartate receptor clustering" EXACT [] +synonym: "NMDA receptor clustering" EXACT [] +is_a: GO:0072578 ! neurotransmitter-gated ion channel clustering +relationship: part_of GO:0001941 ! postsynaptic membrane organization +created_by: pr +creation_date: 2011-07-31T05:30:15Z + +[Term] +id: GO:0097115 +name: neurexin clustering involved in presynaptic membrane assembly +namespace: biological_process +def: "The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals." [GOC:BHF, GOC:sjp, PMID:12796785] +synonym: "neurexin clustering" BROAD [] +synonym: "Nrxn clustering" BROAD [] +synonym: "presynaptic neurexin clustering" EXACT [] +is_a: GO:0043113 ! receptor clustering +intersection_of: GO:0043113 ! receptor clustering +intersection_of: part_of GO:0097105 ! presynaptic membrane assembly +relationship: part_of GO:0097105 ! presynaptic membrane assembly +created_by: pr +creation_date: 2011-07-31T05:40:00Z + +[Term] +id: GO:0097116 +name: gephyrin clustering involved in postsynaptic density assembly +namespace: biological_process +def: "The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses." [GOC:BHF, GOC:sjp, PMID:15620359, PMID:24552784, PMID:25772192] +synonym: "Geph clustering" BROAD [] +is_a: GO:0035418 ! protein localization to synapse +intersection_of: GO:0035418 ! protein localization to synapse +intersection_of: part_of GO:0097107 ! postsynaptic density assembly +relationship: part_of GO:0097107 ! postsynaptic density assembly +created_by: pr +creation_date: 2011-07-31T05:42:29Z + +[Term] +id: GO:0097117 +name: guanylate kinase-associated protein clustering +namespace: biological_process +def: "The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons." [GOC:BHF, GOC:sjp, PMID:15620359] +synonym: "GKAP clustering" EXACT [] +is_a: GO:0072657 ! protein localization to membrane +relationship: part_of GO:0001941 ! postsynaptic membrane organization +created_by: pr +creation_date: 2011-07-31T05:44:35Z + +[Term] +id: GO:0097118 +name: neuroligin clustering involved in postsynaptic membrane assembly +namespace: biological_process +def: "The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons." [GOC:BHF, GOC:sjp, PMID:12796785] +synonym: "neuroligin clustering" BROAD [] +synonym: "Nlgn clustering" BROAD [] +synonym: "postsynaptic neuroligin clustering" EXACT [] +is_a: GO:0043113 ! receptor clustering +intersection_of: GO:0043113 ! receptor clustering +intersection_of: part_of GO:0097104 ! postsynaptic membrane assembly +relationship: part_of GO:0097104 ! postsynaptic membrane assembly +created_by: pr +creation_date: 2011-07-31T05:47:25Z + +[Term] +id: GO:0097119 +name: postsynaptic density protein 95 clustering +namespace: biological_process +def: "The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins." [GOC:BHF, GOC:sjp, PMID:10433269] +synonym: "Dlg4 clustering" EXACT [] +synonym: "post-synaptic density protein 95 clustering" EXACT [] +synonym: "PSD-95 clustering" EXACT [] +is_a: GO:0072657 ! protein localization to membrane +relationship: part_of GO:0001941 ! postsynaptic membrane organization +relationship: part_of GO:0097106 ! postsynaptic density organization +created_by: pr +creation_date: 2011-07-31T05:49:44Z + +[Term] +id: GO:0097120 +name: receptor localization to synapse +namespace: biological_process +def: "Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, GOC:sjp, PMID:21525273] +synonym: "receptor localisation to synapse" EXACT [] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0035418 ! protein localization to synapse +created_by: pr +creation_date: 2011-07-31T09:20:30Z + +[Term] +id: GO:0097121 +name: cyclin A1-CDK1 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:41:25Z + +[Term] +id: GO:0097122 +name: cyclin A2-CDK1 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:42:24Z + +[Term] +id: GO:0097123 +name: cyclin A1-CDK2 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:43:18Z + +[Term] +id: GO:0097124 +name: cyclin A2-CDK2 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:44:19Z + +[Term] +id: GO:0097125 +name: cyclin B1-CDK1 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:45:15Z + +[Term] +id: GO:0097126 +name: cyclin B2-CDK1 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:46:17Z + +[Term] +id: GO:0097127 +name: cyclin B3-CDK2 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:47:16Z + +[Term] +id: GO:0097128 +name: cyclin D1-CDK4 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619, PR:000026740] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:48:36Z + +[Term] +id: GO:0097129 +name: cyclin D2-CDK4 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:53:15Z + +[Term] +id: GO:0097130 +name: cyclin D3-CDK4 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:54:17Z + +[Term] +id: GO:0097131 +name: cyclin D1-CDK6 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:55:26Z + +[Term] +id: GO:0097132 +name: cyclin D2-CDK6 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:56:34Z + +[Term] +id: GO:0097133 +name: cyclin D3-CDK6 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:57:41Z + +[Term] +id: GO:0097134 +name: cyclin E1-CDK2 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619, PR:000026745] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:58:42Z + +[Term] +id: GO:0097135 +name: cyclin E2-CDK2 complex +namespace: cellular_component +def: "A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [GOC:so, PMID:15935619, PR:000026746] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: pr +creation_date: 2011-08-01T01:59:57Z + +[Term] +id: GO:0097136 +name: Bcl-2 family protein complex +namespace: cellular_component +def: "A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed." [GOC:so, PMID:14634621] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2011-08-02T01:34:19Z + +[Term] +id: GO:0097137 +name: BAD-BCL-xl complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:36:06Z + +[Term] +id: GO:0097138 +name: BAD-BCL-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:37:50Z + +[Term] +id: GO:0097139 +name: BID-BCL-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:40:31Z + +[Term] +id: GO:0097140 +name: BIM-BCL-xl complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:41:30Z + +[Term] +id: GO:0097141 +name: BIM-BCL-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:42:31Z + +[Term] +id: GO:0097142 +name: PUMA-BCL-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:43:18Z + +[Term] +id: GO:0097143 +name: PUMA-BCL-xl complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:44:10Z + +[Term] +id: GO:0097144 +name: BAX complex +namespace: cellular_component +def: "An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:45:15Z + +[Term] +id: GO:0097145 +name: BAK complex +namespace: cellular_component +def: "An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:48:11Z + +[Term] +id: GO:0097146 +name: NOXA-BCL-xl complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:49:00Z + +[Term] +id: GO:0097147 +name: NOXA-BCL-2 complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:50:14Z + +[Term] +id: GO:0097148 +name: BCL-2 complex +namespace: cellular_component +def: "A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:bhm, GOC:so, PMID:14634621] +is_a: GO:0097136 ! Bcl-2 family protein complex +created_by: pr +creation_date: 2011-08-02T01:51:16Z + +[Term] +id: GO:0097149 +name: centralspindlin complex +namespace: cellular_component +def: "A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals)." [GOC:ans, PMID:11782313, PMID:16236794] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0072686 ! mitotic spindle +created_by: pr +creation_date: 2011-08-04T11:15:37Z + +[Term] +id: GO:0097150 +name: neuronal stem cell population maintenance +namespace: biological_process +def: "Any process in by an organism or tissue maintains a population of neuronal stem cells." [CL:0000047, GOC:dos, GOC:yaf, PMID:11399758] +is_a: GO:0019827 ! stem cell population maintenance +created_by: pr +creation_date: 2011-08-04T11:18:28Z + +[Term] +id: GO:0097151 +name: positive regulation of inhibitory postsynaptic potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential." [GOC:BHF, GOC:sjp, PMID:18550748] +synonym: "positive regulation of inhibitory post-synaptic membrane potential" EXACT [] +synonym: "positive regulation of IPSP" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:0098828 ! modulation of inhibitory postsynaptic potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: positively_regulates GO:0060080 ! inhibitory postsynaptic potential +relationship: positively_regulates GO:0060080 ! inhibitory postsynaptic potential +created_by: pr +creation_date: 2011-08-12T10:07:45Z + +[Term] +id: GO:0097152 +name: mesenchymal cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833] +synonym: "mesenchymal cell apoptosis" NARROW [] +is_a: GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2011-09-06T02:31:59Z + +[Term] +id: GO:0097153 +name: cysteine-type endopeptidase activity involved in apoptotic process +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process." [GOC:mtg_apoptosis] +synonym: "caspase activity" BROAD [] +synonym: "metacaspase activity" NARROW [GOC:mtg_apoptosis] +xref: Reactome:R-HSA-6800797 "The PIDDosome activates CASP2" +is_a: GO:0004197 ! cysteine-type endopeptidase activity +intersection_of: GO:0004197 ! cysteine-type endopeptidase activity +intersection_of: part_of GO:0006915 ! apoptotic process +relationship: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2011-09-09T10:21:56Z + +[Term] +id: GO:0097154 +name: GABAergic neuron differentiation +namespace: biological_process +def: "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron." [GOC:kmv, PMID:11517269] +is_a: GO:0030182 ! neuron differentiation +created_by: pr +creation_date: 2011-09-14T09:39:11Z + +[Term] +id: GO:0097155 +name: fasciculation of sensory neuron axon +namespace: biological_process +def: "The collection of sensory neuron axons into a bundle of rods, known as a fascicle." [GOC:lb, PMID:18403711] +is_a: GO:0007413 ! axonal fasciculation +created_by: pr +creation_date: 2011-09-16T09:17:34Z + +[Term] +id: GO:0097156 +name: fasciculation of motor neuron axon +namespace: biological_process +def: "The collection of motor neuron axons into a bundle of rods, known as a fascicle." [GOC:lb, PMID:18403711] +is_a: GO:0007413 ! axonal fasciculation +created_by: pr +creation_date: 2011-09-16T09:20:46Z + +[Term] +id: GO:0097157 +name: pre-mRNA intronic binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA)." [GOC:ans, PMID:16260624] +synonym: "pre-messenger RNA intronic binding" EXACT [] +is_a: GO:0036002 ! pre-mRNA binding +created_by: pr +creation_date: 2011-09-23T11:27:01Z + +[Term] +id: GO:0097158 +name: pre-mRNA intronic pyrimidine-rich binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA)." [GOC:ans, PMID:16260624, PMID:16777844] +synonym: "pre-messenger RNA intronic pyrimidine-rich binding" EXACT [] +is_a: GO:0097157 ! pre-mRNA intronic binding +created_by: pr +creation_date: 2011-09-23T11:29:03Z + +[Term] +id: GO:0097159 +name: organic cyclic compound binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." [GOC:sjw, PMID:7583672] +is_a: GO:0005488 ! binding +created_by: pr +creation_date: 2011-09-23T02:31:01Z + +[Term] +id: GO:0097160 +name: polychlorinated biphenyl binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings." [GOC:sjw, PMID:7583672] +synonym: "PCB binding" EXACT [] +synonym: "polychlorobiphenyl binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: pr +creation_date: 2011-09-23T02:33:22Z + +[Term] +id: GO:0097161 +name: DH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket." [GOC:yaf, InterPro:IPR000219, PMID:12775584] +is_a: GO:0019904 ! protein domain specific binding +created_by: pr +creation_date: 2011-09-27T10:06:09Z + +[Term] +id: GO:0097162 +name: MADS box domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs." [GOC:yaf, InterPro:IPR002100, PMID:18296735, Wikipedia:MADS-box] +is_a: GO:0019904 ! protein domain specific binding +created_by: pr +creation_date: 2011-09-27T10:10:59Z + +[Term] +id: GO:0097163 +name: sulfur carrier activity +namespace: molecular_function +def: "Covalently binding to sulfur and delivering it to an acceptor molecule." [GOC:imk, PMID:16387657] +is_a: GO:0140104 ! molecular carrier activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14455 xsd:anyURI +created_by: pr +creation_date: 2011-09-27T10:15:41Z + +[Term] +id: GO:0097164 +name: ammonium ion metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the ammonium ion." [GOC:dhl, GOC:tb, PMID:14671018] +synonym: "ammonium ion metabolism" EXACT [] +synonym: "ammonium metabolic process" RELATED [] +is_a: GO:0006807 ! nitrogen compound metabolic process +created_by: pr +creation_date: 2011-09-28T04:21:30Z + +[Term] +id: GO:0097165 +name: nuclear stress granule +namespace: cellular_component +def: "A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress." [GOC:ans, PMID:10359787, PMID:12865437] +is_a: GO:0035770 ! ribonucleoprotein granule +relationship: part_of GO:0005634 ! nucleus +created_by: pr +creation_date: 2011-09-28T07:49:55Z + +[Term] +id: GO:0097166 +name: lens epithelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [CL:0002224, GOC:yaf, PMID:18423449, Wikipedia:Lens_%28anatomy%29#Lens_epithelium] +is_a: GO:0050673 ! epithelial cell proliferation +relationship: part_of GO:0002088 ! lens development in camera-type eye +created_by: pr +creation_date: 2011-09-29T01:27:50Z + +[Term] +id: GO:0097167 +name: circadian regulation of translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours." [GOC:ans, PMID:17264215] +synonym: "regulation of mRNA translation in response to circadian clock" EXACT [] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0007623 ! circadian rhythm +is_a: GO:0032501 ! multicellular organismal process +created_by: pr +creation_date: 2011-09-29T03:13:31Z + +[Term] +id: GO:0097168 +name: mesenchymal stem cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [CL:0000134, GOC:yaf, PMID:20626275] +synonym: "MSC proliferation" EXACT [] +is_a: GO:0072089 ! stem cell proliferation +created_by: pr +creation_date: 2011-09-29T04:44:48Z + +[Term] +id: GO:0097169 +name: AIM2 inflammasome complex +namespace: cellular_component +def: "A protein complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA." [GOC:vp, PMID:20303873] +is_a: GO:0061702 ! inflammasome complex +created_by: pr +creation_date: 2011-10-03T07:36:21Z + +[Term] +id: GO:0097170 +name: ADP-L-glycero-beta-D-manno-heptose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate." [GOC:yaf] +synonym: "ADP-L-glycero-beta-D-manno-heptose metabolism" EXACT [] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process +created_by: pr +creation_date: 2011-10-03T09:12:58Z + +[Term] +id: GO:0097171 +name: ADP-L-glycero-beta-D-manno-heptose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate." [GOC:yaf, UniPathway:UPA00356] +synonym: "ADP-L-glycero-beta-D-manno-heptose anabolism" EXACT [] +synonym: "ADP-L-glycero-beta-D-manno-heptose biosynthesis" EXACT [] +synonym: "ADP-L-glycero-beta-D-manno-heptose formation" EXACT [] +synonym: "ADP-L-glycero-beta-D-manno-heptose synthesis" EXACT [] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0097170 ! ADP-L-glycero-beta-D-manno-heptose metabolic process +created_by: pr +creation_date: 2011-10-03T09:15:03Z + +[Term] +id: GO:0097172 +name: N-acetylmuramic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine." [GOC:yaf] +synonym: "N-acetylmuramate metabolic process" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramate metabolism" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramic acid metabolism" EXACT [PubChem_Compound:5462244] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +created_by: pr +creation_date: 2011-10-07T12:45:24Z + +[Term] +id: GO:0097173 +name: N-acetylmuramic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine." [GOC:yaf, UniPathway:UPA00342] +synonym: "N-acetylmuramate breakdown" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramate catabolic process" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramate catabolism" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramate degradation" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramic acid breakdown" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramic acid catabolism" EXACT [PubChem_Compound:5462244] +synonym: "N-acetylmuramic acid degradation" EXACT [PubChem_Compound:5462244] +is_a: GO:0046348 ! amino sugar catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0097172 ! N-acetylmuramic acid metabolic process +created_by: pr +creation_date: 2011-10-07T12:48:47Z + +[Term] +id: GO:0097174 +name: 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid." [GOC:yaf, PMID:15901686] +synonym: "1,6-anhydro-N-acetyl-beta-muramate metabolic process" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramate metabolism" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramic acid metabolism" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid metabolic process" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid metabolism" EXACT [] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: pr +creation_date: 2011-10-07T12:54:36Z + +[Term] +id: GO:0097175 +name: 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid." [GOC:yaf, PMID:15901686, UniPathway:UPA00343] +synonym: "1,6-anhydro-N-acetyl-beta-muramate breakdown" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramate catabolic process" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramate catabolism" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramate degradation" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramic acid breakdown" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramic acid catabolism" EXACT [] +synonym: "1,6-anhydro-N-acetyl-beta-muramic acid degradation" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramate breakdown" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramate catabolic process" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramate catabolism" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramate degradation" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid breakdown" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid catabolic process" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid catabolism" EXACT [] +synonym: "1,6-anhydro-N-acetylmuramic acid degradation" EXACT [] +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0097174 ! 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +created_by: pr +creation_date: 2011-10-07T12:58:32Z + +[Term] +id: GO:0097176 +name: epoxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers." [GOC:rs, PMID:15822179] +synonym: "epoxide metabolism" EXACT [] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: pr +creation_date: 2011-10-10T11:29:49Z + +[Term] +id: GO:0097177 +name: mitochondrial ribosome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell." [GOC:ans, PMID:20739282] +is_a: GO:0043022 ! ribosome binding +created_by: pr +creation_date: 2011-10-11T03:03:03Z + +[Term] +id: GO:0097178 +name: ruffle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42." [GOC:yaf, http:en.wikipedia.org/wiki/Membrane_ruffling, PMID:12556481] +synonym: "membrane ruffle formation" EXACT [] +synonym: "membrane ruffling" EXACT [] +is_a: GO:0031529 ! ruffle organization +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +created_by: pr +creation_date: 2011-10-16T01:46:09Z + +[Term] +id: GO:0097179 +name: protease inhibitor complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity." [GOC:ans, PMID:6323392] +synonym: "peptidase inhibitor complex" BROAD [] +is_a: GO:1904090 ! peptidase inhibitor complex +created_by: pr +creation_date: 2011-10-16T08:53:44Z + +[Term] +id: GO:0097180 +name: serine protease inhibitor complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity." [GOC:ans, PMID:6323392] +synonym: "serine-type endopeptidase inhibitor complex" EXACT [GOC:bf, GOC:pr] +synonym: "serpin complex" EXACT [] +is_a: GO:0097179 ! protease inhibitor complex +created_by: pr +creation_date: 2011-10-16T08:55:17Z + +[Term] +id: GO:0097181 +name: protein C inhibitor-coagulation factor V complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V." [GOC:ans, PMID:6323392] +synonym: "PCI-coagulation factor V complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-coagulation factor V complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-F5 complex" EXACT [PR:000007300] +synonym: "serpin A5-coagulation factor V complex" EXACT [PR:000014685] +synonym: "SERPINA5-coagulation factor V complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: pr +creation_date: 2011-10-16T08:57:03Z + +[Term] +id: GO:0097182 +name: protein C inhibitor-coagulation factor Xa complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa." [GOC:ans, PMID:6323392] +synonym: "PCI-coagulation factor Xa complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-coagulation factor Xa complex" EXACT [PR:000014685] +synonym: "serpin A5-coagulation factor Xa complex" EXACT [PR:000014685] +synonym: "SERPINA5-coagulation factor Xa complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: pr +creation_date: 2011-10-16T09:01:29Z + +[Term] +id: GO:0097183 +name: protein C inhibitor-coagulation factor XI complex +namespace: cellular_component +def: "A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI." [GOC:ans, PMID:2844223] +synonym: "PCI-coagulation factor XI complex" EXACT [PR:000014685] +synonym: "plasma serine protease inhibitor-coagulation factor XI complex" EXACT [PR:000014685] +synonym: "protein C inhibitor-F11 complex" EXACT [PR:000007295] +synonym: "serpin A5-coagulation factor XI complex" EXACT [PR:000014685] +synonym: "SERPINA5-coagulation factor XI complex" EXACT [PR:000014685] +is_a: GO:0097180 ! serine protease inhibitor complex +created_by: pr +creation_date: 2011-10-16T09:03:22Z + +[Term] +id: GO:0097184 +name: response to azide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus." [GOC:yaf, PMID:16846222] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound +created_by: pr +creation_date: 2011-11-16T10:00:58Z + +[Term] +id: GO:0097185 +name: cellular response to azide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus." [GOC:yaf, PMID:16846222] +is_a: GO:0071241 ! cellular response to inorganic substance +is_a: GO:0097184 ! response to azide +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: pr +creation_date: 2011-11-16T10:04:41Z + +[Term] +id: GO:0097186 +name: amelogenesis +namespace: biological_process +def: "The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] +synonym: "enamel development" EXACT [] +is_a: GO:0042475 ! odontogenesis of dentin-containing tooth +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +created_by: pr +creation_date: 2011-11-21T09:01:24Z + +[Term] +id: GO:0097187 +name: dentinogenesis +namespace: biological_process +def: "The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] +synonym: "dentin development" EXACT [] +synonym: "dentine development" EXACT [] +is_a: GO:0042475 ! odontogenesis of dentin-containing tooth +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +created_by: pr +creation_date: 2011-11-21T09:04:17Z + +[Term] +id: GO:0097188 +name: dentin mineralization +namespace: biological_process +def: "The process in which calcium salts are deposited into the calcareous tooth structure known as dentin." [GOC:sl, PMID:10206335, PMID:21196346] +synonym: "dentine mineralization" EXACT [] +is_a: GO:0034505 ! tooth mineralization +relationship: part_of GO:0097187 ! dentinogenesis +created_by: pr +creation_date: 2011-11-21T09:05:43Z + +[Term] +id: GO:0097189 +name: apoptotic body +namespace: cellular_component +def: "A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um." [GOC:mtg_apoptosis, GOC:vesicles, PMID:15242875, PMID:24223256, Wikipedia:Apoptosis, Wikipedia:Bleb_(cell_biology)] +synonym: "apoptotic bleb" RELATED [GOC:vesicles] +synonym: "apoptotic vesicle" EXACT [GOC:vesicles] +is_a: GO:1903561 ! extracellular vesicle +created_by: pr +creation_date: 2011-11-22T08:05:20Z + +[Term] +id: GO:0097190 +name: apoptotic signaling pathway +namespace: biological_process +alt_id: GO:0008624 +def: "A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis] +comment: This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways. +synonym: "apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "induction of apoptosis by extracellular signals" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2011-11-23T09:30:23Z + +[Term] +id: GO:0097191 +name: extrinsic apoptotic signaling pathway +namespace: biological_process +def: "A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, GOC:yaf, PMID:17340152] +comment: Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer. +synonym: "death receptor-mediated apoptosis" NARROW [] +synonym: "extrinsic apoptosis" NARROW [] +synonym: "extrinsic apoptotic pathway" EXACT [] +synonym: "extrinsic apoptotic signaling pathway in presence of ligand" NARROW [] +synonym: "extrinsic apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:0007166 ! cell surface receptor signaling pathway +is_a: GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-23T09:34:28Z + +[Term] +id: GO:0097192 +name: extrinsic apoptotic signaling pathway in absence of ligand +namespace: biological_process +def: "A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, PMID:15044679, PMID:20816705] +comment: For dependence receptors, absence of a ligand or withdrawal of a ligand from a receptor acts as a signal. An example of 'extrinsic apoptotic signaling pathway in absence of ligand' is withdrawal of a growth factor such as NGF, even if traditionally apoptosis induced via growth factor withdrawal has been classified as an instance of intrinsic apoptosis. See an example in PMID:19767770. Ligands whose withdrawal or absence induce apoptosis should be annotated to GO:2001239 'regulation of extrinsic apoptotic signaling pathway in absence of ligand', rather than to the pathway term itself. Examples of gene products that may be annotated to GO:0097192 'extrinsic apoptotic signaling pathway in absence of ligand' include dependence receptors such as DCC or UNC5B, which relay lethal signals in the absence of their ligand (netrin-1). In the case of DCC and UNC5B, the signaling proceeds through the assembly of a DRAL- and TUCAN- (or NLRP1-) containing caspase-9-activating complex or by the dephosphorylation-mediated activation of death-associated protein kinase 1 (DAPK1) by UNC5B-bound protein phosphatase 2A (PP2A), respectively. DAPK1 can mediate the direct activation of executioner caspases or favor MOMP (reviewed in PMID:21760595). Also see PMID:21172653 (annotations to UNC5B and PR65beta, UniProt symbols O08722, PPP2R1B and P30154). +synonym: "dependence receptor signaling pathway" RELATED [] +synonym: "extrinsic apoptosis in absence of ligand" NARROW [] +synonym: "extrinsic apoptotic signalling pathway in absence of ligand" EXACT [GOC:mah] +is_a: GO:0038034 ! signal transduction in absence of ligand +is_a: GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-23T09:37:09Z + +[Term] +id: GO:0097193 +name: intrinsic apoptotic signaling pathway +namespace: biological_process +alt_id: GO:0008629 +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." [GOC:mtg_apoptosis, GOC:yaf, PMID:11919192, PMID:17340152, PMID:18852119] +comment: The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969S3 and Q99683) in PMID:21771788. A diagram of the intrinsic apoptotic pathway including examples of molecular players can be found in Figure 2 in PMID:21760595. +synonym: "induction of apoptosis by intracellular signals" RELATED [] +synonym: "intrinsic apoptosis" NARROW [] +synonym: "intrinsic apoptotic pathway" EXACT [] +synonym: "intrinsic apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "mitochondrial-mediated apoptotic pathway" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction +is_a: GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-23T09:40:50Z + +[Term] +id: GO:0097194 +name: execution phase of apoptosis +namespace: biological_process +def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595] +synonym: "apoptosis" NARROW [] +synonym: "execution phase of apoptotic process" EXACT [] +is_a: GO:0009987 ! cellular process +relationship: has_part GO:0032060 ! bleb assembly +relationship: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2011-11-23T09:45:24Z + +[Term] +id: GO:0097195 +name: pilomotor reflex +namespace: biological_process +def: "The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect." [GOC:BHF, PMID:21335239, Wikipedia:Pilomotor_reflex] +synonym: "goosebump reflex" EXACT [] +synonym: "horripilation" EXACT [] +synonym: "piloerection" EXACT [] +is_a: GO:0060004 ! reflex +created_by: pr +creation_date: 2011-12-01T05:08:14Z + +[Term] +id: GO:0097196 +name: Shu complex +namespace: cellular_component +def: "A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p." [GOC:jh, PMID:15654096, PMID:19496932] +is_a: GO:1990391 ! DNA repair complex +created_by: pr +creation_date: 2011-12-01T05:11:08Z + +[Term] +id: GO:0097197 +name: tetraspanin-enriched microdomain +namespace: cellular_component +def: "A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities." [GOC:ans, PMID:19709882, PMID:21930792] +synonym: "membrane tetraspanin-enriched microdomain" EXACT [] +synonym: "TEM" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +created_by: pr +creation_date: 2011-12-02T04:21:37Z + +[Term] +id: GO:0097198 +name: histone H3-K36 trimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone." [GOC:se, PMID:17948059] +is_a: GO:0010452 ! histone H3-K36 methylation +is_a: GO:0018023 ! peptidyl-lysine trimethylation +created_by: pr +creation_date: 2011-12-05T01:19:45Z + +[Term] +id: GO:0097199 +name: cysteine-type endopeptidase activity involved in apoptotic signaling pathway +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway." [GOC:mtg_apoptosis, PMID:11717445, Wikipedia:Caspase] +comment: Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases. +synonym: "activator caspase activity" NARROW [] +synonym: "apical caspase activity" NARROW [] +synonym: "cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "initiator caspase activity" NARROW [] +is_a: GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process +intersection_of: GO:0004197 ! cysteine-type endopeptidase activity +intersection_of: part_of GO:0097190 ! apoptotic signaling pathway +relationship: part_of GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-12-12T01:43:00Z + +[Term] +id: GO:0097200 +name: cysteine-type endopeptidase activity involved in execution phase of apoptosis +namespace: molecular_function +def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis." [GOC:mtg_apoptosis, Wikipedia:Caspase] +comment: Examples of gene products that may be annotated to this term include CASP3, CASP6 and CASP7, also called effector (or executioner) caspases. +synonym: "effector caspase activity" NARROW [] +synonym: "executioner caspase activity" NARROW [] +is_a: GO:0097153 ! cysteine-type endopeptidase activity involved in apoptotic process +intersection_of: GO:0004197 ! cysteine-type endopeptidase activity +intersection_of: part_of GO:0097194 ! execution phase of apoptosis +relationship: part_of GO:0097194 ! execution phase of apoptosis +created_by: pr +creation_date: 2011-12-12T01:46:06Z + +[Term] +id: GO:0097201 +name: negative regulation of transcription from RNA polymerase II promoter in response to stress +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:rn, PMID:11027285, PMID:15575969, PMID:16556235, PMID:18086556, PMID:18627600] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +created_by: pr +creation_date: 2011-12-14T09:16:22Z + +[Term] +id: GO:0097202 +name: activation of cysteine-type endopeptidase activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase." [GOC:mtg_apoptosis, PMID:21726810] +comment: This term should be used to annotate gene products within the context of cellular processes other than apoptotic cell death (e.g., cell cycle arrest). To annotate gene products involved in activation of cysteine-type endopeptidases where the activation results in apoptotic process, please use the more granular term GO:0006919. +synonym: "activation of caspase activity" NARROW [] +synonym: "activation of metacaspase activity" RELATED [] +is_a: GO:0031638 ! zymogen activation +is_a: GO:2001056 ! positive regulation of cysteine-type endopeptidase activity +created_by: pr +creation_date: 2011-12-19T02:44:04Z + +[Term] +id: GO:0097203 +name: phagocytic cup lip +namespace: cellular_component +def: "The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome." [GOC:pf, PMID:20200225] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0001891 ! phagocytic cup +created_by: pr +creation_date: 2011-12-21T10:26:41Z + +[Term] +id: GO:0097204 +name: phagocytic cup base +namespace: cellular_component +def: "The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking." [GOC:pf, PMID:20200225] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0001891 ! phagocytic cup +created_by: pr +creation_date: 2011-12-21T10:29:07Z + +[Term] +id: GO:0097205 +name: renal filtration +namespace: biological_process +def: "A renal system process in which fluid circulating through the body is filtered through a barrier system." [GOC:pr, GOC:sart] +is_a: GO:0003014 ! renal system process +created_by: pr +creation_date: 2012-01-03T03:10:17Z + +[Term] +id: GO:0097206 +name: nephrocyte filtration +namespace: biological_process +def: "The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm." [GOC:sart, PMID:18971929] +is_a: GO:0097205 ! renal filtration +created_by: pr +creation_date: 2012-01-03T03:13:31Z + +[Term] +id: GO:0097207 +name: bud dormancy process +namespace: biological_process +def: "A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud." [GOC:PO_curators, PO_REF:00009] +comment: Bud dormancy may precede dormancy of the whole plant. +synonym: "bud dormancy" RELATED [] +is_a: GO:0022611 ! dormancy process +is_a: GO:0032501 ! multicellular organismal process +created_by: pr +creation_date: 2012-01-04T01:18:24Z + +[Term] +id: GO:0097208 +name: alveolar lamellar body +namespace: cellular_component +def: "A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant." [GOC:cjm, Wikipedia:Lamellar_granule] +is_a: GO:0042599 ! lamellar body +created_by: pr +creation_date: 2012-01-04T02:33:04Z + +[Term] +id: GO:0097209 +name: epidermal lamellar body +namespace: cellular_component +def: "A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function." [GOC:cjm, Wikipedia:Lamellar_granule] +is_a: GO:0042599 ! lamellar body +created_by: pr +creation_date: 2012-01-04T02:34:27Z + +[Term] +id: GO:0097210 +name: response to gonadotropin-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus." [GOC:yaf, PMID:15976007] +synonym: "response to GnRH" EXACT [] +is_a: GO:0043434 ! response to peptide hormone +created_by: pr +creation_date: 2012-01-09T08:48:56Z + +[Term] +id: GO:0097211 +name: cellular response to gonadotropin-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus." [GOC:yaf, PMID:15976007] +synonym: "cellular response to GnRH" EXACT [] +synonym: "cellular response to gonadotrophin-releasing hormone" EXACT [GOC:dph] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:0097210 ! response to gonadotropin-releasing hormone +created_by: pr +creation_date: 2012-01-09T08:51:23Z + +[Term] +id: GO:0097212 +name: lysosomal membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." [GOC:yaf, PMID:20544854] +synonym: "lysosomal membrane organisation" EXACT [GOC:mah] +synonym: "lysosome membrane organization" EXACT [] +is_a: GO:0061024 ! membrane organization +relationship: part_of GO:0007040 ! lysosome organization +created_by: pr +creation_date: 2012-01-12T10:16:15Z + +[Term] +id: GO:0097213 +name: regulation of lysosomal membrane permeability +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane." [GOC:yaf, PMID:20544854] +synonym: "regulation of lysosome membrane permeability" EXACT [] +is_a: GO:0090559 ! regulation of membrane permeability +is_a: GO:0097212 ! lysosomal membrane organization +created_by: pr +creation_date: 2012-01-12T10:19:44Z + +[Term] +id: GO:0097214 +name: positive regulation of lysosomal membrane permeability +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane." [GOC:yaf, PMID:20544854] +synonym: "positive regulation of lysosome membrane permeability" EXACT [] +is_a: GO:0097213 ! regulation of lysosomal membrane permeability +is_a: GO:1905710 ! positive regulation of membrane permeability +created_by: pr +creation_date: 2012-01-12T10:22:17Z + +[Term] +id: GO:0097215 +name: negative regulation of lysosomal membrane permeability +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane." [GOC:yaf, PMID:20544854] +synonym: "negative regulation of lysosome membrane permeability" EXACT [] +is_a: GO:0097213 ! regulation of lysosomal membrane permeability +is_a: GO:1905709 ! negative regulation of membrane permeability +created_by: pr +creation_date: 2012-01-12T10:23:42Z + +[Term] +id: GO:0097216 +name: guanosine tetraphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions." [GOC:imk, PMID:15109491, PMID:16968770, PMID:18359660] +synonym: "5'-ppGpp-3' binding" EXACT [] +is_a: GO:0032550 ! purine ribonucleoside binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +created_by: pr +creation_date: 2012-01-13T08:35:50Z + +[Term] +id: GO:0097217 +name: sieve area +namespace: cellular_component +def: "A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements." [ISBN:0471738433, POC:curators] +comment: Part of a sieve element (PO:0025406). +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009505 ! plant-type cell wall +created_by: pr +creation_date: 2012-01-13T05:39:03Z + +[Term] +id: GO:0097218 +name: sieve plate +namespace: cellular_component +def: "A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas." [ISBN:0471738433, POC:curators] +comment: Typical of angiosperms. Part of sieve tube member (PO:0000289). +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097217 ! sieve area +relationship: part_of GO:0009505 ! plant-type cell wall +created_by: pr +creation_date: 2012-01-13T05:42:48Z + +[Term] +id: GO:0097219 +name: compound sieve plate +namespace: cellular_component +def: "A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement." [ISBN:0471738433, POC:curators] +comment: Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell. +is_a: GO:0097218 ! sieve plate +created_by: pr +creation_date: 2012-01-13T05:45:23Z + +[Term] +id: GO:0097220 +name: simple sieve plate +namespace: cellular_component +def: "A sieve plate that contains a single specialized sieve area." [ISBN:0471738433, POC:curators] +comment: Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell. +is_a: GO:0097218 ! sieve plate +created_by: pr +creation_date: 2012-01-13T05:46:46Z + +[Term] +id: GO:0097221 +name: M/G1 phase-specific MADS box-forkhead transcription factor complex +namespace: cellular_component +def: "A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2." [GOC:mah, PMID:18057023] +synonym: "PBF complex" NARROW [] +synonym: "PBF transcription complex" NARROW [GOC:vw] +synonym: "PCB binding factor complex" NARROW [] +synonym: "pombe cell cycle box binding factor complex" NARROW [] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: pr +creation_date: 2012-01-18T08:18:27Z + +[Term] +id: GO:0097222 +name: mitochondrial mRNA polyadenylation +namespace: biological_process +def: "The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails." [GOC:ans, PMID:18083837] +is_a: GO:0006378 ! mRNA polyadenylation +is_a: GO:0090616 ! mitochondrial mRNA 3'-end processing +intersection_of: GO:0006378 ! mRNA polyadenylation +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: pr +creation_date: 2012-01-24T02:47:19Z + +[Term] +id: GO:0097223 +name: obsolete sperm part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid." [GOC:cjm] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_obsolete: true +consider: CL:0000019 +created_by: pr +creation_date: 2012-01-25T01:19:35Z + +[Term] +id: GO:0097224 +name: sperm connecting piece +namespace: cellular_component +def: "The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum." [GOC:cjm, MP:0009830] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:21:02Z + +[Term] +id: GO:0097225 +name: sperm midpiece +namespace: cellular_component +def: "The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece." [GOC:cjm, MP:0009831] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:23:41Z + +[Term] +id: GO:0097226 +name: sperm mitochondrial sheath +namespace: cellular_component +def: "The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum." [GOC:cjm, MP:0009832] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:25:08Z + +[Term] +id: GO:0097227 +name: sperm annulus +namespace: cellular_component +def: "The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity." [GOC:cjm, MP:0009834] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:26:17Z + +[Term] +id: GO:0097228 +name: sperm principal piece +namespace: cellular_component +def: "The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece." [GOC:cjm, MP:0009836] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:27:27Z + +[Term] +id: GO:0097229 +name: sperm end piece +namespace: cellular_component +def: "The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane." [GOC:cjm, GOC:sart, MP:0009837] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0036126 ! sperm flagellum +created_by: pr +creation_date: 2012-01-25T01:29:04Z + +[Term] +id: GO:0097230 +name: cell motility in response to potassium ion +namespace: biological_process +def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus." [GOC:pf, PMID:19363786, PMID:21239624] +synonym: "K+ facilitation of cell motility" EXACT [] +synonym: "potassium ion facilitation of cell motility" EXACT [] +is_a: GO:0048870 ! cell motility +relationship: part_of GO:0035865 ! cellular response to potassium ion +created_by: pr +creation_date: 2012-01-25T04:39:45Z + +[Term] +id: GO:0097231 +name: cell motility in response to calcium ion +namespace: biological_process +def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus." [GOC:pf, PMID:19363786, PMID:21239624, PMID:8937985] +synonym: "Ca2+ facilitation of cell motility" EXACT [] +synonym: "calcium ion facilitation of cell motility" EXACT [] +is_a: GO:0048870 ! cell motility +relationship: part_of GO:0071277 ! cellular response to calcium ion +created_by: pr +creation_date: 2012-01-25T04:42:45Z + +[Term] +id: GO:0097232 +name: lamellar body membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome." [GOC:sl, PMID:11940594] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0042599 ! lamellar body +created_by: pr +creation_date: 2012-01-26T10:28:42Z + +[Term] +id: GO:0097233 +name: alveolar lamellar body membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant." [GOC:sl, PMID:11940594] +is_a: GO:0097232 ! lamellar body membrane +relationship: part_of GO:0097208 ! alveolar lamellar body +created_by: pr +creation_date: 2012-01-26T10:30:24Z + +[Term] +id: GO:0097234 +name: epidermal lamellar body membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function." [GOC:sl, PMID:11940594] +is_a: GO:0097232 ! lamellar body membrane +relationship: part_of GO:0097209 ! epidermal lamellar body +created_by: pr +creation_date: 2012-01-26T10:32:13Z + +[Term] +id: GO:0097235 +name: obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:1899286] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: pr +creation_date: 2012-02-01T05:07:12Z + +[Term] +id: GO:0097236 +name: obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions." [GOC:dgf, PMID:19702872] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: pr +creation_date: 2012-02-01T09:33:11Z + +[Term] +id: GO:0097237 +name: cellular response to toxic substance +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0070887 ! cellular response to chemical stimulus +created_by: pr +creation_date: 2012-02-02T12:23:31Z + +[Term] +id: GO:0097238 +name: cellular response to methylglyoxal +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal." [GOC:pr] +is_a: GO:0051595 ! response to methylglyoxal +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0110096 ! cellular response to aldehyde +is_a: GO:1901655 ! cellular response to ketone +created_by: pr +creation_date: 2012-02-02T12:26:35Z + +[Term] +id: GO:0097239 +name: positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus." [GOC:dgf, PMID:15773992] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +relationship: part_of GO:0097238 ! cellular response to methylglyoxal +created_by: pr +creation_date: 2012-02-02T12:28:46Z + +[Term] +id: GO:0097240 +name: chromosome attachment to the nuclear envelope +namespace: biological_process +def: "The process in which chromatin is anchored to the nuclear envelope." [GOC:vw, PMID:22156749] +synonym: "attachment of chromatin to nuclear envelope" RELATED [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0050000 ! chromosome localization +created_by: pr +creation_date: 2012-02-07T01:11:37Z + +[Term] +id: GO:0097241 +name: hematopoietic stem cell migration to bone marrow +namespace: biological_process +def: "The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:yaf, PMID:17368745] +synonym: "hematopoietic stem cell homing" BROAD [] +synonym: "hemopoietic stem cell migration to bone marrow" EXACT [] +synonym: "progenitor cell homing" BROAD [] +is_a: GO:0035701 ! hematopoietic stem cell migration +created_by: pr +creation_date: 2012-02-09T01:08:32Z + +[Term] +id: GO:0097242 +name: amyloid-beta clearance +namespace: biological_process +def: "The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors." [GOC:aruk, GOC:bc, GOC:BHF, PMID:18289866, PMID:19098903, PMID:26005850] +synonym: "beta-amyloid clearance" EXACT [] +is_a: GO:0032501 ! multicellular organismal process +created_by: pr +creation_date: 2012-02-16T05:32:29Z + +[Term] +id: GO:0097243 +name: flavonoid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge." [GOC:sl, PMID:20599706] +is_a: GO:0005488 ! binding +created_by: pr +creation_date: 2012-02-17T03:49:16Z + +[Term] +id: GO:0097244 +name: flavonol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone." [GOC:sl] +is_a: GO:0043168 ! anion binding +is_a: GO:0097243 ! flavonoid binding +created_by: pr +creation_date: 2012-02-17T03:50:45Z + +[Term] +id: GO:0097245 +name: flavanol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a flavanol." [GOC:sl] +synonym: "flavan-3-ol binding" NARROW [] +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0097243 ! flavonoid binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: pr +creation_date: 2012-02-17T03:52:10Z + +[Term] +id: GO:0097246 +name: catechin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure." [GOC:sl] +is_a: GO:0097245 ! flavanol binding +created_by: pr +creation_date: 2012-02-17T03:53:54Z + +[Term] +id: GO:0097247 +name: epigallocatechin 3-gallate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin." [GOC:sl, PMID:21307292] +synonym: "catechin gallate binding" BROAD [] +synonym: "EGCG binding" EXACT [] +is_a: GO:0008144 ! drug binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:0097243 ! flavonoid binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: pr +creation_date: 2012-02-17T03:55:05Z + +[Term] +id: GO:0097248 +name: maintenance of protein location in cell cortex of cell tip +namespace: biological_process +def: "A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell." [GOC:al, PMID:19646873] +is_a: GO:0032065 ! maintenance of protein location in cell cortex +created_by: pr +creation_date: 2012-02-20T04:27:31Z + +[Term] +id: GO:0097250 +name: mitochondrial respirasome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex." [GOC:mcc, PMID:21909073, PMID:22342701] +synonym: "mitochondrial respiratory chain supercomplex assembly" EXACT [] +synonym: "mitochondrial respiratory supercomplex assembly" EXACT [] +is_a: GO:0007005 ! mitochondrion organization +is_a: GO:0034622 ! cellular protein-containing complex assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/12846 xsd:anyURI +created_by: pr +creation_date: 2012-02-23T05:18:41Z + +[Term] +id: GO:0097251 +name: leukotriene B4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents." [GOC:yaf, UniPathway:UPA00878] +synonym: "leukotriene B4 anabolism" EXACT [] +synonym: "leukotriene B4 biosynthesis" EXACT [] +synonym: "leukotriene B4 formation" EXACT [] +synonym: "leukotriene B4 synthesis" EXACT [] +synonym: "LTB4 anabolism" EXACT [] +synonym: "LTB4 biosynthesis" EXACT [] +synonym: "LTB4 formation" EXACT [] +synonym: "LTB4 synthesis" EXACT [] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0019370 ! leukotriene biosynthetic process +is_a: GO:0036102 ! leukotriene B4 metabolic process +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +created_by: pr +creation_date: 2012-02-24T09:34:01Z + +[Term] +id: GO:0097252 +name: oligodendrocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons." [CL:0000128, GOC:mtg_apoptosis, GOC:yaf, PMID:16723520] +synonym: "oligodendrocyte apoptosis" NARROW [] +is_a: GO:0034349 ! glial cell apoptotic process +created_by: pr +creation_date: 2012-03-05T10:51:15Z + +[Term] +id: GO:0097253 +name: beta-hydroxybutyrate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid." [GOC:dsf, PMID:22302940] +synonym: "(R)-3-hydroxybutyrate transmembrane transporter activity" EXACT [] +synonym: "3-hydroxybutanoic acid transmembrane transporter activity" EXACT [] +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +created_by: pr +creation_date: 2012-03-05T01:22:37Z + +[Term] +id: GO:0097254 +name: renal tubular secretion +namespace: biological_process +def: "Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:10049739, Wikipedia:Renal_secretion#Secretion] +is_a: GO:0003014 ! renal system process +is_a: GO:0046903 ! secretion +created_by: pr +creation_date: 2012-03-05T02:03:58Z + +[Term] +id: GO:0097255 +name: R2TP complex +namespace: cellular_component +def: "A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others." [GOC:mcc, PMID:15766533, PMID:21925213] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2012-03-06T11:16:33Z + +[Term] +id: GO:0097256 +name: phenyllactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the oxidation of phenyllactate to produce phenylpyruvate." [GOC:pde, PMID:15421980] +comment: This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU). +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +created_by: pr +creation_date: 2012-03-07T11:39:39Z + +[Term] +id: GO:0097257 +name: leukotriene B4 12-hydroxy dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+)." [GOC:mw, KEGG_REACTION:R03864, PMID:8394361, PMID:9461497] +synonym: "leukotriene B4 12-hydroxydehydrogenase activity" EXACT [] +xref: Reactome:R-HSA-2161567 "LTB4 is oxidised to 12-oxoLTB4 by PTGR1" +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +created_by: pr +creation_date: 2012-03-07T02:07:41Z + +[Term] +id: GO:0097258 +name: 20-hydroxy-leukotriene B4 omega oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + NADPH + H(+) = 20-aldehyde-leukotriene B4 + 2H2O + NADP(+)." [GOC:mw, PMID:2836406] +synonym: "20-hydroxy-leukotriene B4 omega-oxidase activity" EXACT [] +synonym: "20-hydroxy-leukotriene B4 omega-oxidation" RELATED [] +xref: Reactome:R-HSA-2161745 "20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3" +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +created_by: pr +creation_date: 2012-03-07T03:37:53Z + +[Term] +id: GO:0097259 +name: 20-aldehyde-leukotriene B4 20-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 20-aldehyde-leukotriene B4 + O2 + NADPH + H(+) = 20-carboxy-leukotriene B4 + H2O + NADP(+)." [GOC:mw, PMID:2549038, PMID:2836406] +xref: Reactome:R-HSA-2161792 "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3" +xref: Reactome:R-HSA-2161979 "20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH" +is_a: GO:0004497 ! monooxygenase activity +created_by: pr +creation_date: 2012-03-07T03:40:05Z + +[Term] +id: GO:0097260 +name: eoxin A4 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: leukotriene A4 = eoxin A4." [GOC:mw, PMID:18184802, PMID:18647347] +xref: Reactome:R-HSA-2162019 "LTA4 is converted to EXA4 by ALOX15" +is_a: GO:0016853 ! isomerase activity +created_by: pr +creation_date: 2012-03-08T02:57:23Z + +[Term] +id: GO:0097261 +name: eoxin C4 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4." [GOC:mw, PMID:18184802, PMID:18647347] +xref: Reactome:R-HSA-2161768 "EXA4 is converted to EXC4 by LTC4S" +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: pr +creation_date: 2012-03-08T02:59:00Z + +[Term] +id: GO:0097262 +name: eoxin D4 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid." [GOC:mw, PMID:18184802, PMID:18647347] +xref: Reactome:R-HSA-2161945 "EXC4 is converted to EXD4 by GGT" +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups +created_by: pr +creation_date: 2012-03-08T03:01:00Z + +[Term] +id: GO:0097263 +name: eoxin E4 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine." [GOC:mw, PMID:18184802, PMID:18647347] +xref: Reactome:R-HSA-2161868 "EXD4 is converted to EXE4 by DPEP" +is_a: GO:0008238 ! exopeptidase activity +created_by: pr +creation_date: 2012-03-08T03:02:48Z + +[Term] +id: GO:0097264 +name: self proteolysis +namespace: biological_process +def: "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds." [GOC:yaf, PMID:18676612, PMID:19144634] +synonym: "autolysis" BROAD [] +synonym: "self-proteolysis" EXACT [] +is_a: GO:0006508 ! proteolysis +created_by: pr +creation_date: 2012-03-09T12:43:24Z + +[Term] +id: GO:0097265 +name: 5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+)." [GOC:mw, PMID:1326548] +synonym: "5(S)-HETE dehydrogenase activity" EXACT [] +synonym: "5-HETE dehydrogenase activity" EXACT [] +synonym: "5-hydroxy-eicosatetraenoic acid dehydrogenase activity" EXACT [] +xref: Reactome:R-HSA-2161776 "5S-HETE is oxidised to 5-oxoETE by 5-HEDH" +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: pr +creation_date: 2012-03-09T12:46:02Z + +[Term] +id: GO:0097266 +name: phenylacetyl-CoA 1,2-epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)." [EC:1.14.13.149, GOC:bf, GOC:gk, PMID:20660314, PMID:21247899] +synonym: "phenylacetyl-CoA epoxidase activity" EXACT [GOC:bf] +synonym: "phenylacetyl-CoA monooxygenase activity" EXACT [EC:1.14.13.149] +synonym: "ring 1,2-phenylacetyl-CoA epoxidase activity" EXACT [EC:1.14.13.149] +xref: EC:1.14.13.149 +xref: KEGG_REACTION:R09838 +xref: RHEA:32171 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: pr +creation_date: 2012-03-13T09:22:47Z + +[Term] +id: GO:0097267 +name: omega-hydroxylase P450 pathway +namespace: biological_process +def: "The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation." [GOC:mw, PMID:10681399] +synonym: "P450 omega-hydroxylase pathway" EXACT [] +is_a: GO:0019369 ! arachidonic acid metabolic process +created_by: pr +creation_date: 2012-03-15T12:58:15Z + +[Term] +id: GO:0097268 +name: cytoophidium +namespace: cellular_component +def: "A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human." [GOC:mag, PMID:20513629, PMID:21930098, Wikipedia:CTP_synthase#Cytoophidium] +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2012-03-15T01:00:20Z + +[Term] +id: GO:0097269 +name: all-trans-decaprenyl-diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate." [EC:2.5.1.91, GOC:mw, PMID:16262699] +synonym: "(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" EXACT [] +synonym: "2-trans,6-trans-farnesyl diphosphate activity" EXACT [] +xref: Reactome:R-HSA-2162253 "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: pr +creation_date: 2012-03-20T01:00:23Z + +[Term] +id: GO:0097270 +name: dishabituation +namespace: biological_process +def: "The temporary recovery of response to a stimulus when a novel stimulus is added." [GOC:kmv, PMID:11390637, Wikipedia:Habituation] +is_a: GO:0046958 ! nonassociative learning +created_by: pr +creation_date: 2012-03-20T01:39:25Z + +[Term] +id: GO:0097271 +name: protein localization to bud neck +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location within a cellular bud neck." [GOC:rb, PMID:22344253] +synonym: "protein localisation to bud neck" EXACT [GOC:mah] +synonym: "protein localization to cellular bud neck" EXACT [] +is_a: GO:0034613 ! cellular protein localization +created_by: pr +creation_date: 2012-03-20T03:39:20Z + +[Term] +id: GO:0097272 +name: ammonia homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of ammonia." [GOC:yaf, PMID:12695560] +is_a: GO:0048878 ! chemical homeostasis +created_by: pr +creation_date: 2012-03-22T02:51:22Z + +[Term] +id: GO:0097273 +name: creatinine homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of creatinine." [GOC:yaf, PMID:12695560] +is_a: GO:0048878 ! chemical homeostasis +created_by: pr +creation_date: 2012-03-22T02:52:50Z + +[Term] +id: GO:0097274 +name: urea homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of urea." [GOC:yaf, PMID:12695560] +is_a: GO:0048878 ! chemical homeostasis +created_by: pr +creation_date: 2012-03-22T02:53:39Z + +[Term] +id: GO:0097275 +name: cellular ammonia homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of ammonia at the level of the cell." [GOC:yaf, PMID:12695560] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:0097272 ! ammonia homeostasis +created_by: pr +creation_date: 2012-03-22T02:54:38Z + +[Term] +id: GO:0097276 +name: cellular creatinine homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell." [GOC:yaf, PMID:12695560] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:0097273 ! creatinine homeostasis +created_by: pr +creation_date: 2012-03-22T02:55:46Z + +[Term] +id: GO:0097277 +name: cellular urea homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell." [GOC:yaf, PMID:12695560] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:0097274 ! urea homeostasis +created_by: pr +creation_date: 2012-03-22T02:57:08Z + +[Term] +id: GO:0097278 +name: complement-dependent cytotoxicity +namespace: biological_process +def: "Cell killing caused by the membrane attack complex formed following complement activation." [GOC:add, GOC:rv] +is_a: GO:0001906 ! cell killing +relationship: has_part GO:0006956 ! complement activation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18715 xsd:anyURI +created_by: pr +creation_date: 2012-03-22T05:04:04Z + +[Term] +id: GO:0097279 +name: histamine secretion mediated by IgE immunoglobulin +namespace: biological_process +def: "Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen." [GOC:add, GOC:rv] +synonym: "histamine secretion mediated by IgE antibody" EXACT [] +synonym: "Ig-mediated histamine release" BROAD [] +is_a: GO:0097280 ! histamine secretion mediated by immunoglobulin +created_by: pr +creation_date: 2012-03-22T06:42:13Z + +[Term] +id: GO:0097280 +name: histamine secretion mediated by immunoglobulin +namespace: biological_process +def: "Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface." [GOC:add, GOC:rv, PMID:11490155, PMID:1719184] +is_a: GO:0002437 ! inflammatory response to antigenic stimulus +is_a: GO:0002441 ! histamine secretion involved in inflammatory response +relationship: has_part GO:0003823 ! antigen binding +created_by: pr +creation_date: 2012-03-26T01:30:25Z + +[Term] +id: GO:0097281 +name: immune complex formation +namespace: biological_process +def: "The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus." [GOC:add, GOC:rv] +synonym: "antibody-mediated agglutination" EXACT [] +is_a: GO:0016064 ! immunoglobulin mediated immune response +relationship: has_part GO:0003823 ! antigen binding +created_by: pr +creation_date: 2012-03-26T01:35:21Z + +[Term] +id: GO:0097282 +name: immunoglobulin-mediated neutralization +namespace: biological_process +def: "The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin." [GOC:add, GOC:rv] +synonym: "antibody-mediated neutralization" EXACT [] +is_a: GO:0016064 ! immunoglobulin mediated immune response +relationship: has_part GO:0003823 ! antigen binding +created_by: pr +creation_date: 2012-03-26T01:55:24Z + +[Term] +id: GO:0097283 +name: keratinocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin." [CL:0000312, GOC:jc, GOC:mtg_apoptosis, PMID:10201527] +synonym: "keratinocyte apoptosis" NARROW [] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: pr +creation_date: 2012-03-29T10:20:51Z + +[Term] +id: GO:0097284 +name: hepatocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] +synonym: "hepatocyte apoptosis" NARROW [] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: pr +creation_date: 2012-03-29T10:23:21Z + +[Term] +id: GO:0097285 +name: obsolete cell-type specific apoptotic process +namespace: biological_process +def: "OBSOLETE. Any apoptotic process in a specific cell type." [GOC:mtg_apoptosis] +comment: This term was made obsolete because it was an unnecessary grouping term. +synonym: "cell-type specific apoptosis" NARROW [] +is_obsolete: true +consider: GO:0006915 +created_by: pr +creation_date: 2012-03-29T04:00:25Z + +[Term] +id: GO:0097287 +name: 7-cyano-7-deazaguanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo." [GOC:yaf, PMID:364423] +synonym: "7-cyano-7-deazaguanine metabolism" EXACT [] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0050898 ! nitrile metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: pr +creation_date: 2012-04-25T10:50:50Z + +[Term] +id: GO:0097288 +name: 7-cyano-7-deazaguanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo." [GOC:yaf, PMID:364423, UniPathway:UPA00391] +synonym: "7-cyano-7-deazaguanine anabolism" EXACT [] +synonym: "7-cyano-7-deazaguanine biosynthesis" EXACT [] +synonym: "7-cyano-7-deazaguanine formation" EXACT [] +synonym: "7-cyano-7-deazaguanine synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0080028 ! nitrile biosynthetic process +is_a: GO:0097287 ! 7-cyano-7-deazaguanine metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: pr +creation_date: 2012-04-25T10:53:47Z + +[Term] +id: GO:0097289 +name: alpha-ribazole metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)." [GOC:yaf] +synonym: "alpha-ribazole metabolism" EXACT [] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901657 ! glycosyl compound metabolic process +created_by: pr +creation_date: 2012-04-25T11:49:24Z + +[Term] +id: GO:0097290 +name: alpha-ribazole biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)." [GOC:yaf, MetaCyc:PWY-5508, MetaCyc:PWY-6269, UniPathway:UPA00061] +synonym: "alpha-ribazole anabolism" EXACT [] +synonym: "alpha-ribazole biosynthesis" EXACT [] +synonym: "alpha-ribazole formation" EXACT [] +synonym: "alpha-ribazole synthesis" EXACT [] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0097289 ! alpha-ribazole metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901659 ! glycosyl compound biosynthetic process +created_by: pr +creation_date: 2012-04-25T11:51:07Z + +[Term] +id: GO:0097291 +name: renal phosphate ion absorption +namespace: biological_process +def: "A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:lb, PMID:18784102, PMID:22506049] +synonym: "renal phosphate absorption" EXACT [] +is_a: GO:0070293 ! renal absorption +created_by: pr +creation_date: 2012-04-25T03:34:48Z + +[Term] +id: GO:0097292 +name: XMP metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving XMP, xanthosine monophosphate." [GOC:yaf] +synonym: "XMP metabolism" EXACT [] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +is_a: GO:0009167 ! purine ribonucleoside monophosphate metabolic process +created_by: pr +creation_date: 2012-04-26T09:51:16Z + +[Term] +id: GO:0097293 +name: XMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate." [GOC:yaf] +synonym: "XMP anabolism" EXACT [] +synonym: "XMP biosynthesis" EXACT [] +synonym: "XMP formation" EXACT [] +synonym: "XMP synthesis" EXACT [] +is_a: GO:0009152 ! purine ribonucleotide biosynthetic process +is_a: GO:0009168 ! purine ribonucleoside monophosphate biosynthetic process +is_a: GO:0097292 ! XMP metabolic process +created_by: pr +creation_date: 2012-04-26T09:54:13Z + +[Term] +id: GO:0097294 +name: 'de novo' XMP biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors." [GOC:yaf, MetaCyc:IMP-DEHYDROG-RXN, UniPathway:UPA00601] +synonym: "'de novo' XMP anabolism" EXACT [] +synonym: "'de novo' XMP biosynthesis" EXACT [] +synonym: "'de novo' XMP formation" EXACT [] +synonym: "'de novo' XMP synthesis" EXACT [] +is_a: GO:0097293 ! XMP biosynthetic process +created_by: pr +creation_date: 2012-04-26T09:57:49Z + +[Term] +id: GO:0097295 +name: morphine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum." [GOC:yaf, UniPathway:UPA00852] +synonym: "morphine anabolism" EXACT [] +synonym: "morphine biosynthesis" EXACT [] +synonym: "morphine formation" EXACT [] +synonym: "morphine synthesis" EXACT [] +is_a: GO:0033075 ! isoquinoline alkaloid biosynthetic process +is_a: GO:0071272 ! morphine metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +created_by: pr +creation_date: 2012-05-02T09:51:19Z + +[Term] +id: GO:0097296 +name: activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway." [GOC:mtg_apoptosis] +comment: Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. +synonym: "activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [] +synonym: "activation of initiator caspase activity" NARROW [] +is_a: GO:2001269 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +created_by: pr +creation_date: 2012-05-02T03:19:35Z + +[Term] +id: GO:0097297 +name: activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +namespace: biological_process +def: "Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis." [GOC:mtg_apoptosis] +comment: Note that this term should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the execution phase of apoptosis (also known as an effector caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. +synonym: "activation of effector caspase activity" NARROW [] +is_a: GO:2001272 ! positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +created_by: pr +creation_date: 2012-05-02T03:23:01Z + +[Term] +id: GO:0097298 +name: regulation of nucleus size +namespace: biological_process +def: "Any process that modulates the size of the nucleus." [GOC:al, GOC:mah, PMID:19366728] +synonym: "regulation of nuclear size" EXACT [] +synonym: "regulation of nuclear volume" EXACT [] +is_a: GO:0032535 ! regulation of cellular component size +created_by: pr +creation_date: 2012-05-03T06:21:43Z + +[Term] +id: GO:0097299 +name: obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response +namespace: molecular_function +def: "OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen." [GOC:mtg_apoptosis] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "metacaspase activity involved in plant-type hypersensitive response" NARROW [] +is_obsolete: true +created_by: pr +creation_date: 2012-05-04T02:09:55Z + +[Term] +id: GO:0097300 +name: programmed necrotic cell death +namespace: biological_process +def: "A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors." [GOC:mtg_apoptosis, PMID:21760595] +comment: This term may be used when annotating instances of programmed cell death characterized by necrotic morphology where the involvement of RIPK1 and/or RIPK3 is not shown. See PMID:23818611 for some examples. +synonym: "programmed cell death by necrosis" EXACT [] +synonym: "regulated necrosis" BROAD [] +is_a: GO:0012501 ! programmed cell death +is_a: GO:0070265 ! necrotic cell death +created_by: pr +creation_date: 2012-05-04T03:03:39Z + +[Term] +id: GO:0097301 +name: regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, PMID:20412803] +synonym: "cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter" EXACT [] +synonym: "potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter" BROAD [] +is_a: GO:0030007 ! cellular potassium ion homeostasis +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +created_by: pr +creation_date: 2012-05-09T09:03:02Z + +[Term] +id: GO:0097302 +name: lipoprotein biosynthetic process via diacylglyceryl transfer +namespace: biological_process +def: "The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex." [GOC:pde, GOC:yaf, UniPathway:UPA00664] +synonym: "lipoprotein biosynthesis (diacylglyceryl transfer)" EXACT [] +is_a: GO:0042158 ! lipoprotein biosynthetic process +created_by: pr +creation_date: 2012-05-15T01:02:02Z + +[Term] +id: GO:0097303 +name: lipoprotein biosynthetic process via N-acyl transfer +namespace: biological_process +def: "The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex." [GOC:pde, GOC:yaf, UniPathway:UPA00666] +synonym: "lipoprotein biosynthesis (N-acyl transfer)" EXACT [] +is_a: GO:0042158 ! lipoprotein biosynthetic process +created_by: pr +creation_date: 2012-05-15T01:03:59Z + +[Term] +id: GO:0097304 +name: lipoprotein biosynthetic process via signal peptide cleavage +namespace: biological_process +def: "The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex." [GOC:pde, GOC:yaf, UniPathway:UPA00665] +synonym: "lipoprotein biosynthesis (signal peptide cleavage)" EXACT [] +is_a: GO:0042158 ! lipoprotein biosynthetic process +created_by: pr +creation_date: 2012-05-15T01:05:17Z + +[Term] +id: GO:0097305 +name: response to alcohol +namespace: biological_process +alt_id: GO:1990335 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." [GOC:pr, PMID:24014527] +synonym: "process resulting in tolerance to alcohol" NARROW [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-05-15T03:48:45Z + +[Term] +id: GO:0097306 +name: cellular response to alcohol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." [GOC:pr] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: pr +creation_date: 2012-05-15T03:49:51Z + +[Term] +id: GO:0097307 +name: response to farnesol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus." [GOC:pr] +is_a: GO:0033993 ! response to lipid +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +created_by: pr +creation_date: 2012-05-15T03:51:31Z + +[Term] +id: GO:0097308 +name: cellular response to farnesol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus." [GOC:di, PMID:11425711] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:0097307 ! response to farnesol +created_by: pr +creation_date: 2012-05-15T03:54:01Z + +[Term] +id: GO:0097309 +name: cap1 mRNA methylation +namespace: biological_process +def: "Methylation of the ribose of the first nucleotide of a 5'-capped mRNA." [GOC:sp, PMID:20713356] +synonym: "cap1 mRNA capping" BROAD [] +is_a: GO:0036451 ! cap mRNA methylation +created_by: pr +creation_date: 2012-05-23T04:03:13Z + +[Term] +id: GO:0097310 +name: cap2 mRNA methylation +namespace: biological_process +def: "Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA." [GOC:sp, PMID:20713356] +synonym: "cap2 mRNA capping" BROAD [] +is_a: GO:0036451 ! cap mRNA methylation +created_by: pr +creation_date: 2012-05-23T04:05:07Z + +[Term] +id: GO:0097311 +name: bacterial biofilm matrix +namespace: cellular_component +def: "A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria." [GOC:imk, PMID:22571672, Wikipedia:Biofilm] +is_a: GO:0062039 ! biofilm matrix +created_by: pr +creation_date: 2012-05-24T11:20:50Z + +[Term] +id: GO:0097312 +name: obsolete bacterial biofilm matrix component +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria." [GOC:imk, PMID:22571672, Wikipedia:Biofilm] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "biofilm matrix part" EXACT [] +is_obsolete: true +consider: GO:0097311 +created_by: pr +creation_date: 2012-05-24T11:22:56Z + +[Term] +id: GO:0097313 +name: bacterial biofilm matrix surface +namespace: cellular_component +def: "The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria." [GOC:imk, PMID:22571672, Wikipedia:Biofilm] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097311 ! bacterial biofilm matrix +created_by: pr +creation_date: 2012-05-24T11:25:47Z + +[Term] +id: GO:0097314 +name: apoptosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process." [GOC:mtg_apoptosis] +synonym: "apoptosome formation" EXACT [] +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2012-05-28T03:39:49Z + +[Term] +id: GO:0097315 +name: response to N-acetyl-D-glucosamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus." [GOC:di, PMID:21700702] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-05-30T03:58:54Z + +[Term] +id: GO:0097316 +name: cellular response to N-acetyl-D-glucosamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus." [GOC:di, PMID:21700702] +is_a: GO:0071310 ! cellular response to organic substance +is_a: GO:0097315 ! response to N-acetyl-D-glucosamine +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: pr +creation_date: 2012-05-30T04:01:02Z + +[Term] +id: GO:0097317 +name: invasive growth in response to biotic stimulus +namespace: biological_process +def: "The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus." [GOC:di, PMID:18679170] +is_a: GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +is_a: GO:0036267 ! invasive filamentous growth +created_by: pr +creation_date: 2012-05-31T10:38:16Z + +[Term] +id: GO:0097318 +name: invasive growth in response to abiotic stimulus +namespace: biological_process +def: "The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans." [GOC:di, PMID:18679170] +is_a: GO:0009628 ! response to abiotic stimulus +is_a: GO:0036267 ! invasive filamentous growth +created_by: pr +creation_date: 2012-05-31T10:39:31Z + +[Term] +id: GO:0097320 +name: plasma membrane tubulation +namespace: biological_process +def: "A membrane tubulation process occurring in a plasma membrane." [GOC:BHF, GOC:pr, PMID:15252009, PMID:20730103] +synonym: "membrane tubulation" BROAD [] +synonym: "vesicle scission" RELATED [] +is_a: GO:0007009 ! plasma membrane organization +created_by: pr +creation_date: 2012-05-31T10:01:22Z + +[Term] +id: GO:0097321 +name: cell growth mode switching, filamentous to budding +namespace: biological_process +def: "The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans." [GOC:di, PMID:14617167] +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +created_by: pr +creation_date: 2012-06-05T11:28:06Z + +[Term] +id: GO:0097322 +name: 7SK snRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA)." [GOC:nhn, PMID:21853533] +synonym: "7SK small nuclear RNA binding" EXACT [] +is_a: GO:0017069 ! snRNA binding +created_by: pr +creation_date: 2012-06-05T11:42:23Z + +[Term] +id: GO:0097323 +name: B cell adhesion +namespace: biological_process +def: "The attachment of a B cell to another cell via adhesion molecules." [GOC:jc] +is_a: GO:0007159 ! leukocyte cell-cell adhesion +created_by: pr +creation_date: 2012-06-06T01:59:19Z + +[Term] +id: GO:0097324 +name: melanocyte migration +namespace: biological_process +def: "The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance." [CL:0000148, GOC:uh, PMID:22637532] +is_a: GO:0010631 ! epithelial cell migration +created_by: pr +creation_date: 2012-06-08T10:08:18Z + +[Term] +id: GO:0097325 +name: melanocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance." [CL:0000148, GOC:uh, PMID:22637532] +is_a: GO:0050673 ! epithelial cell proliferation +created_by: pr +creation_date: 2012-06-08T10:10:12Z + +[Term] +id: GO:0097326 +name: melanocyte adhesion +namespace: biological_process +def: "The attachment of a melanocyte to another cell via adhesion molecules." [CL:0000148, GOC:uh, PMID:22637532] +is_a: GO:0090136 ! epithelial cell-cell adhesion +created_by: pr +creation_date: 2012-06-08T10:12:03Z + +[Term] +id: GO:0097327 +name: response to antineoplastic agent +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms." [GOC:pr] +is_a: GO:0042493 ! response to drug +created_by: pr +creation_date: 2012-06-12T10:48:28Z + +[Term] +id: GO:0097328 +name: response to carboplatin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus." [GOC:pr] +is_a: GO:0097327 ! response to antineoplastic agent +created_by: pr +creation_date: 2012-06-12T10:50:34Z + +[Term] +id: GO:0097329 +name: response to antimetabolite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." [GOC:pr] +is_a: GO:0042221 ! response to chemical +created_by: pr +creation_date: 2012-06-12T10:52:01Z + +[Term] +id: GO:0097330 +name: response to 5-fluoro-2'-deoxyuridine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-06-12T10:53:35Z + +[Term] +id: GO:0097331 +name: response to cytarabine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1903416 ! response to glycoside +created_by: pr +creation_date: 2012-06-12T10:55:29Z + +[Term] +id: GO:0097332 +name: response to antipsychotic drug +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." [GOC:pr] +is_a: GO:0042493 ! response to drug +created_by: pr +creation_date: 2012-06-12T10:58:13Z + +[Term] +id: GO:0097333 +name: response to olanzapine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097332 ! response to antipsychotic drug +created_by: pr +creation_date: 2012-06-12T11:00:04Z + +[Term] +id: GO:0097334 +name: response to perphenazine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097332 ! response to antipsychotic drug +created_by: pr +creation_date: 2012-06-12T11:01:14Z + +[Term] +id: GO:0097335 +name: response to quetiapine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097332 ! response to antipsychotic drug +created_by: pr +creation_date: 2012-06-12T11:03:22Z + +[Term] +id: GO:0097336 +name: response to risperidone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097332 ! response to antipsychotic drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-06-12T11:04:31Z + +[Term] +id: GO:0097337 +name: response to ziprasidone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms." [GOC:pr] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097332 ! response to antipsychotic drug +created_by: pr +creation_date: 2012-06-12T11:05:31Z + +[Term] +id: GO:0097338 +name: response to clozapine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus." [GOC:pr] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097332 ! response to antipsychotic drug +created_by: pr +creation_date: 2012-06-12T11:07:01Z + +[Term] +id: GO:0097339 +name: glycolate transmembrane transport +namespace: biological_process +def: "The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid)." [GOC:am, PMID:11283302, PMID:11785976] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "glycolate membrane transport" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:1900866 ! glycolate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: pr +creation_date: 2012-06-12T05:12:35Z + +[Term] +id: GO:0097340 +name: inhibition of cysteine-type endopeptidase activity +namespace: biological_process +def: "Any process that prevents the activation of an inactive cysteine-type endopeptidase." [GOC:mtg_apoptosis, PMID:20383739] +synonym: "inhibition of caspase activity" NARROW [] +synonym: "prevention of caspase activity" NARROW [] +synonym: "prevention of cysteine-type endopeptidase activity" EXACT [] +is_a: GO:0097341 ! zymogen inhibition +is_a: GO:2000117 ! negative regulation of cysteine-type endopeptidase activity +created_by: pr +creation_date: 2012-06-18T11:23:05Z + +[Term] +id: GO:0097341 +name: zymogen inhibition +namespace: biological_process +def: "Any process that prevents the proteolytic processing of an inactive enzyme to an active form." [GOC:mtg_apoptosis, PMID:20383739] +synonym: "prevention of zymogen activation" EXACT [] +is_a: GO:0010955 ! negative regulation of protein processing +created_by: pr +creation_date: 2012-06-18T11:25:45Z + +[Term] +id: GO:0097342 +name: ripoptosome +namespace: cellular_component +def: "A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more." [GOC:bhm, GOC:mtg_apoptosis, PMID:22265414, PMID:22274400] +comment: It has been shown that receptor-mediated necroptotic signaling pathway requires assembly of a ripoptosome protein complex consisting of caspase-8, caspase-10, Fas-associated death domain protein (FADD), casp8 and FADD-like apoptosis regulator (CFLAR) as well as the two receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (PMID:21737330). Optionally, depending on the receptor activated, this complex may contain TLR3 adaptor protein TRIF (PMID:21737330). +synonym: "necrosome" RELATED [] +synonym: "TNFR1 complex II" NARROW [PMID:22089168] +synonym: "Tnfr1-CII" NARROW [PMID:22089168] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005829 ! cytosol +created_by: pr +creation_date: 2012-06-18T12:55:34Z + +[Term] +id: GO:0097343 +name: ripoptosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more." [GOC:mtg_apoptosis, PMID:22274400] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pr +creation_date: 2012-06-18T12:57:20Z + +[Term] +id: GO:0097344 +name: Rix1 complex +namespace: cellular_component +def: "A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes." [GOC:vw, PMID:14759368, PMID:15260980, PMID:21385875] +synonym: "IPI complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2012-06-18T01:38:49Z + +[Term] +id: GO:0097345 +name: mitochondrial outer membrane permeabilization +namespace: biological_process +def: "The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:pg, PMID:21041309] +comment: BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively). +synonym: "mitochondrial outer membrane permeabilization" BROAD [] +synonym: "mitochondrial outer membrane permeabilization during apoptotic cell death" BROAD [] +synonym: "MOMP" EXACT [] +is_a: GO:1902110 ! positive regulation of mitochondrial membrane permeability involved in apoptotic process +relationship: part_of GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2012-06-19T04:06:54Z + +[Term] +id: GO:0097346 +name: INO80-type complex +namespace: cellular_component +def: "A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair." [GOC:rb, PMID:19355820] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: pr +creation_date: 2012-06-20T11:26:55Z + +[Term] +id: GO:0097347 +name: TAM protein secretion complex +namespace: cellular_component +def: "A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane." [GOC:am, PMID:22466966] +synonym: "translocation and assembly module protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2012-06-21T10:44:15Z + +[Term] +id: GO:0097348 +name: host cell endocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a host cell endocytic vesicle." [GOC:ecd] +is_a: GO:0044162 ! host cell cytoplasmic vesicle membrane +created_by: pr +creation_date: 2012-06-25T10:31:34Z + +[Term] +id: GO:0097350 +name: neutrophil clearance +namespace: biological_process +def: "The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms." [GOC:BHF, PMID:21957127] +is_a: GO:0048771 ! tissue remodeling +relationship: has_part GO:0006909 ! phagocytosis +relationship: part_of GO:0001780 ! neutrophil homeostasis +created_by: pr +creation_date: 2012-06-27T03:53:38Z + +[Term] +id: GO:0097351 +name: toxin-antitoxin pair type II binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other." [GOC:rs, PMID:19143615, PMID:19325885, PMID:21819231, PMID:22545240, Wikipedia:Toxin-antitoxin_system#Type_II] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:2759 +created_by: pr +creation_date: 2012-06-28T11:41:38Z + +[Term] +id: GO:0097352 +name: autophagosome maturation +namespace: biological_process +alt_id: GO:0000046 +def: "Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling." [GOC:autophagy, GOC:lf, PMID:28077293] +synonym: "autophagic vacuole fusion" EXACT [GOC:autophagy] +synonym: "autophagic vacuole maturation" EXACT [GOC:autophagy] +synonym: "autophagosome fusion" RELATED [] +is_a: GO:0032984 ! protein-containing complex disassembly +relationship: part_of GO:0016236 ! macroautophagy +created_by: pr +creation_date: 2012-06-28T03:12:18Z + +[Term] +id: GO:0097353 +name: centrolateral pattern formation +namespace: biological_process +def: "The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment." [GOC:dsz] +synonym: "mediolateral pattern formation" EXACT [] +is_a: GO:0003002 ! regionalization +created_by: pr +creation_date: 2012-07-02T11:34:08Z + +[Term] +id: GO:0097354 +name: prenylation +namespace: biological_process +def: "The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added." [GOC:di, PMID:18029206, PMID:21351751, PMID:22123822, PMID:22642693, PMID:22660767] +is_a: GO:0044237 ! cellular metabolic process +created_by: pr +creation_date: 2012-07-03T01:12:19Z + +[Term] +id: GO:0097355 +name: protein localization to heterochromatin +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah] +synonym: "protein localisation to heterochromatin" EXACT [GOC:mah] +is_a: GO:0071168 ! protein localization to chromatin +created_by: pr +creation_date: 2012-07-03T03:19:07Z + +[Term] +id: GO:0097356 +name: perinucleolar compartment +namespace: cellular_component +def: "The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC." [GOC:vw, PMID:21385875, Wikipedia:Perinucleolar_compartment] +synonym: "perinucleolar region" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0031981 ! nuclear lumen +created_by: pr +creation_date: 2012-07-03T05:11:01Z + +[Term] +id: GO:0097358 +name: D-leucyl-tRNA(Leu) deacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu)." [GOC:se, PMID:10918062] +is_a: GO:0051499 ! D-aminoacyl-tRNA deacylase activity +created_by: pr +creation_date: 2012-07-04T09:18:12Z + +[Term] +id: GO:0097359 +name: UDP-glucosylation +namespace: biological_process +def: "The covalent attachment of a UDP-glucose residue to a substrate molecule." [GOC:al] +is_a: GO:0006011 ! UDP-glucose metabolic process +created_by: pr +creation_date: 2012-07-06T02:26:35Z + +[Term] +id: GO:0097360 +name: chorionic trophoblast cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278] +is_a: GO:0008283 ! cell population proliferation +created_by: pr +creation_date: 2012-07-19T10:17:37Z + +[Term] +id: GO:0097361 +name: CIA complex +namespace: cellular_component +def: "The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity." [GOC:sp, PMID:22678362] +synonym: "cytosolic iron-sulfur protein assembly complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: pr +creation_date: 2012-07-20T02:07:22Z + +[Term] +id: GO:0097362 +name: MCM8-MCM9 complex +namespace: cellular_component +def: "A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links." [GOC:sp, PMID:22771115, PMID:22771120] +is_a: GO:0042555 ! MCM complex +created_by: pr +creation_date: 2012-07-20T02:10:12Z + +[Term] +id: GO:0097363 +name: protein O-GlcNAc transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine." [GOC:jsg, GOC:sart, PMID:22158438] +synonym: "O-GlcNAc transferase" EXACT [] +synonym: "O-linked N-acetylglucosaminyltransferase" EXACT [] +synonym: "OGTase" EXACT [] +synonym: "UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase" EXACT [] +xref: EC:2.4.1.255 +is_a: GO:0016757 ! transferase activity, transferring glycosyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: pr +creation_date: 2012-07-24T01:46:51Z + +[Term] +id: GO:0097364 +name: stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758] +is_a: GO:0015275 ! stretch-activated, cation-selective, calcium channel activity +intersection_of: GO:0015275 ! stretch-activated, cation-selective, calcium channel activity +intersection_of: regulates GO:0001508 ! action potential +relationship: regulates GO:0001508 ! action potential +created_by: pr +creation_date: 2012-07-25T04:08:33Z + +[Term] +id: GO:0097365 +name: stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:21290758] +is_a: GO:0097364 ! stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential +intersection_of: GO:0015275 ! stretch-activated, cation-selective, calcium channel activity +intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential +relationship: regulates GO:0086001 ! cardiac muscle cell action potential +created_by: pr +creation_date: 2012-07-26T02:39:10Z + +[Term] +id: GO:0097366 +name: response to bronchodilator +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to bronchodilator agent" EXACT [] +synonym: "response to broncholytic agent" RELATED [] +is_a: GO:0042493 ! response to drug +created_by: pr +creation_date: 2012-08-01T16:13:31Z + +[Term] +id: GO:0097367 +name: carbohydrate derivative binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a carbohydrate derivative." [GOC:pr] +subset: goslim_agr +subset: goslim_mouse +is_a: GO:0005488 ! binding +created_by: pr +creation_date: 2012-08-02T13:03:39Z + +[Term] +id: GO:0097368 +name: establishment of Sertoli cell barrier +namespace: biological_process +def: "Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions." [GOC:sl, PMID:19509333, Wikipedia:Blood-testis_barrier] +synonym: "establishment of blood-testis barrier" EXACT [] +synonym: "establishment of BTB" EXACT [] +synonym: "establishment of SCB" EXACT [] +is_a: GO:0060009 ! Sertoli cell development +created_by: pr +creation_date: 2012-08-02T17:05:55Z + +[Term] +id: GO:0097370 +name: protein O-GlcNAcylation via threonine +namespace: biological_process +def: "The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine." [GOC:pr, GOC:sart, PMID:22158438] +is_a: GO:0018243 ! protein O-linked glycosylation via threonine +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: pr +creation_date: 2012-08-06T16:57:37Z + +[Term] +id: GO:0097371 +name: MDM2/MDM4 family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53." [InterPro:IPR016495] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2012-08-08T16:20:59Z + +[Term] +id: GO:0097372 +name: NAD-dependent histone deacetylase activity (H3-K18 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein." [EC:3.5.1.17, GOC:sp, PMID:22722849, RHEA:24548] +is_a: GO:0017136 ! NAD-dependent histone deacetylase activity +is_a: GO:0034739 ! histone deacetylase activity (H4-K16 specific) +created_by: pr +creation_date: 2012-09-05T13:16:39Z + +[Term] +id: GO:0097373 +name: MCM core complex +namespace: cellular_component +def: "A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated." [GOC:mah, PMID:10770926, PMID:15007098, PMID:9305914] +synonym: "MCM4/6/7 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2012-09-12T10:41:42Z + +[Term] +id: GO:0097374 +name: sensory neuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses." [CL:0000101, GOC:pr] +is_a: GO:0007411 ! axon guidance +created_by: pr +creation_date: 2012-10-01T10:16:22Z + +[Term] +id: GO:0097375 +name: spinal sensory neuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord." [CL:0009000, GOC:pr, GOC:yaf] +is_a: GO:0097374 ! sensory neuron axon guidance +created_by: pr +creation_date: 2012-10-01T10:17:20Z + +[Term] +id: GO:0097376 +name: interneuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions." [CL:0000099, GOC:pr] +is_a: GO:0007411 ! axon guidance +created_by: pr +creation_date: 2012-10-01T10:18:35Z + +[Term] +id: GO:0097377 +name: spinal cord interneuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord." [CL:0005000, GOC:pr] +is_a: GO:0097376 ! interneuron axon guidance +created_by: pr +creation_date: 2012-10-01T10:19:42Z + +[Term] +id: GO:0097378 +name: dorsal spinal cord interneuron axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord." [GOC:yaf] +synonym: "dorsal interneuron axon guidance" EXACT [] +is_a: GO:0097377 ! spinal cord interneuron axon guidance +created_by: pr +creation_date: 2012-10-01T10:20:48Z + +[Term] +id: GO:0097379 +name: dorsal spinal cord interneuron posterior axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:yaf, PMID:19545367] +synonym: "dorsal interneuron caudal axon projection" RELATED [] +is_a: GO:0033564 ! anterior/posterior axon guidance +is_a: GO:0097378 ! dorsal spinal cord interneuron axon guidance +created_by: pr +creation_date: 2012-10-01T10:22:38Z + +[Term] +id: GO:0097380 +name: dorsal spinal cord interneuron anterior axon guidance +namespace: biological_process +def: "The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:yaf, PMID:19545367] +synonym: "dorsal interneuron rostral axon projection" RELATED [] +is_a: GO:0033564 ! anterior/posterior axon guidance +is_a: GO:0097378 ! dorsal spinal cord interneuron axon guidance +created_by: pr +creation_date: 2012-10-01T10:24:41Z + +[Term] +id: GO:0097381 +name: photoreceptor disc membrane +namespace: cellular_component +def: "Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane." [GOC:bj, GOC:krc, GOC:pde, PMID:11826267, PMID:19501669, PMID:2537204, PMID:26574505, PMID:6771304, PMID:7507907] +is_a: GO:0016020 ! membrane +relationship: part_of GO:0001750 ! photoreceptor outer segment +created_by: pr +creation_date: 2012-10-05T11:01:22Z + +[Term] +id: GO:0097382 +name: deoxynucleoside-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate." [GOC:pde] +is_a: GO:0016462 ! pyrophosphatase activity +created_by: pr +creation_date: 2012-10-11T16:03:22Z + +[Term] +id: GO:0097383 +name: dIDP diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: dIDP + H2O = dIMP + phosphate." [GOC:pde, PMID:20385596] +synonym: "deoxyinosine-diphosphatase activity" EXACT [] +xref: Reactome:R-HSA-2509793 "NUDT16 hydrolyses dIDP to dIMP" +is_a: GO:0097382 ! deoxynucleoside-diphosphatase activity +created_by: pr +creation_date: 2012-10-11T16:04:40Z + +[Term] +id: GO:0097384 +name: cellular lipid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells." [GOC:pr] +synonym: "cellular lipid anabolism" EXACT [] +synonym: "cellular lipid biosynthesis" EXACT [] +synonym: "cellular lipid formation" EXACT [] +synonym: "cellular lipid synthesis" EXACT [] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044255 ! cellular lipid metabolic process +created_by: pr +creation_date: 2012-10-16T16:47:09Z + +[Term] +id: GO:0097385 +name: programmed necrotic cell death in response to starvation +namespace: biological_process +def: "A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment)." [GOC:mtg_apoptosis, GOC:pg, PMID:13679856] +synonym: "necrotic cell death in response to starvation" BROAD [] +is_a: GO:0042594 ! response to starvation +is_a: GO:0097300 ! programmed necrotic cell death +created_by: pr +creation_date: 2012-10-22T09:02:18Z + +[Term] +id: GO:0097386 +name: glial cell projection +namespace: cellular_component +def: "A prolongation or process extending from a glial cell." [GOC:mc] +synonym: "glial process" RELATED [] +synonym: "glial projection" RELATED [] +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: pr +creation_date: 2012-10-22T13:55:54Z + +[Term] +id: GO:0097387 +name: capitate projection +namespace: cellular_component +def: "Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies)." [GOC:mc, PMID:3098431] +is_a: GO:0097386 ! glial cell projection +created_by: pr +creation_date: 2012-10-22T13:57:10Z + +[Term] +id: GO:0097388 +name: chemokine (C-C motif) ligand 19 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CCL19 production" EXACT [] +synonym: "EBI1 ligand chemokine production" EXACT [] +synonym: "ELC production" EXACT [] +synonym: "macrophage inflammatory protein-3-beta production" EXACT [] +synonym: "MIP-3-beta production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: pr +creation_date: 2012-10-23T07:54:10Z + +[Term] +id: GO:0097389 +name: chemokine (C-C motif) ligand 21 production +namespace: biological_process +def: "The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CCL21 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: pr +creation_date: 2012-10-23T07:56:26Z + +[Term] +id: GO:0097390 +name: chemokine (C-X-C motif) ligand 12 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CXCL12 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: pr +creation_date: 2012-10-23T07:57:28Z + +[Term] +id: GO:0097391 +name: chemokine (C-X-C motif) ligand 13 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CXCL13 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: pr +creation_date: 2012-10-23T07:58:28Z + +[Term] +id: GO:0097392 +name: chemokine (C-X-C motif) ligand 16 production +namespace: biological_process +def: "The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:rv] +synonym: "CXCL16 production" EXACT [] +is_a: GO:0032602 ! chemokine production +created_by: pr +creation_date: 2012-10-23T07:59:43Z + +[Term] +id: GO:0097393 +name: telomeric repeat-containing RNA transcription +namespace: biological_process +def: "The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome." [GOC:al, PMID:22139915] +synonym: "TERRA transcription" EXACT [PMID:22139915] +is_a: GO:0006351 ! transcription, DNA-templated +created_by: pr +creation_date: 2012-10-23T10:06:17Z + +[Term] +id: GO:0097394 +name: telomeric repeat-containing RNA transcription by RNA polymerase II +namespace: biological_process +def: "The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter." [GOC:al, PMID:22139915] +synonym: "telomeric repeat-containing RNA transcription from RNA pol II promoter" EXACT [] +synonym: "telomeric RNA transcription from Pol II promoter" RELATED [] +synonym: "TERRA RNA transcription from RNA pol II promoter" RELATED [GOC:22139915] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:0097393 ! telomeric repeat-containing RNA transcription +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14854 xsd:anyURI +created_by: pr +creation_date: 2012-10-23T10:09:15Z + +[Term] +id: GO:0097395 +name: response to interleukin-32 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus." [GOC:pr] +synonym: "response to IL-32" EXACT [] +is_a: GO:0034097 ! response to cytokine +created_by: pr +creation_date: 2012-10-23T13:21:16Z + +[Term] +id: GO:0097396 +name: response to interleukin-17 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus." [GOC:pr] +synonym: "response to IL-17" EXACT [] +is_a: GO:0034097 ! response to cytokine +created_by: pr +creation_date: 2012-10-23T13:22:28Z + +[Term] +id: GO:0097397 +name: cellular response to interleukin-32 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus." [GOC:pr] +synonym: "cellular response to IL-32" EXACT [] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:0097395 ! response to interleukin-32 +created_by: pr +creation_date: 2012-10-23T13:23:22Z + +[Term] +id: GO:0097398 +name: cellular response to interleukin-17 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus." [GOC:pr] +synonym: "cellular response to IL-17" EXACT [] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:0097396 ! response to interleukin-17 +created_by: pr +creation_date: 2012-10-23T13:25:43Z + +[Term] +id: GO:0097399 +name: interleukin-32-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:ic, PMID:21602493] +synonym: "IL-32-mediated signaling pathway" EXACT [] +synonym: "IL-32-mediated signalling pathway" EXACT [] +synonym: "interleukin-32-mediated signalling pathway" EXACT [] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0097397 ! cellular response to interleukin-32 +created_by: pr +creation_date: 2012-10-23T13:27:22Z + +[Term] +id: GO:0097400 +name: interleukin-17-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:ic, PMID:21602493] +synonym: "IL-17-mediated signaling pathway" EXACT [] +synonym: "IL-17-mediated signalling pathway" EXACT [] +synonym: "interleukin-17-mediated signalling pathway" EXACT [] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +relationship: part_of GO:0097398 ! cellular response to interleukin-17 +created_by: pr +creation_date: 2012-10-23T13:30:03Z + +[Term] +id: GO:0097401 +name: synaptic vesicle lumen acidification +namespace: biological_process +def: "The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading." [GOC:dsf, PMID:21172605, PMID:22875945] +subset: goslim_synapse +synonym: "synaptic vesicle lumen pH reduction" EXACT [] +synonym: "synaptic vesicle proton loading" EXACT syngo_official_label [] +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0070050 ! neuron cellular homeostasis +is_a: GO:1902600 ! proton transmembrane transport +relationship: part_of GO:0016188 ! synaptic vesicle maturation +relationship: part_of GO:0099504 ! synaptic vesicle cycle +created_by: pr +creation_date: 2012-10-25T09:03:34Z + +[Term] +id: GO:0097402 +name: neuroblast migration +namespace: biological_process +def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145] +is_a: GO:0016477 ! cell migration +created_by: pr +creation_date: 2012-10-29T08:24:37Z + +[Term] +id: GO:0097403 +name: cellular response to raffinose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus." [GOC:al] +is_a: GO:0071322 ! cellular response to carbohydrate stimulus +is_a: GO:1901545 ! response to raffinose +created_by: pr +creation_date: 2012-10-29T10:30:46Z + +[Term] +id: GO:0097407 +name: Bunina body +namespace: cellular_component +def: "Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles." [NIF_Subcellular:nlx_subcell_20090101, PMID:18026741] +xref: NIF_Subcellular:nlx_subcell_20090101 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-10-31T13:52:30Z + +[Term] +id: GO:0097408 +name: fibrillary inclusion +namespace: cellular_component +def: "Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra." [NIF_Subcellular:sao967812059] +xref: NIF_Subcellular:sao967812059 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-10-31T13:53:58Z + +[Term] +id: GO:0097409 +name: glial cytoplasmic inclusion +namespace: cellular_component +def: "Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy." [NIF_Subcellular:nlx_subcell_20090703, PMID:21562886, PMID:2559165] +synonym: "GCI" EXACT [] +synonym: "Papp-Lantos body" RELATED [] +xref: NIF_Subcellular:nlx_subcell_20090703 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-10-31T13:55:11Z + +[Term] +id: GO:0097410 +name: hippocampal interneuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron." [CL:1001569, GOC:jc, PMID:19655320] +is_a: GO:0021879 ! forebrain neuron differentiation +is_a: GO:0021895 ! cerebral cortex neuron differentiation +relationship: part_of GO:0021766 ! hippocampus development +created_by: pr +creation_date: 2012-11-04T10:58:28Z + +[Term] +id: GO:0097411 +name: hypoxia-inducible factor-1alpha signaling pathway +namespace: biological_process +def: "A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia." [GOC:bf, GOC:jc, http://www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway] +synonym: "HIF1alpha pathway" EXACT [] +synonym: "hypoxia-inducible factor signaling" EXACT [GOC:bf] +synonym: "hypoxia-inducible factor-1alpha signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0071456 ! cellular response to hypoxia +created_by: pr +creation_date: 2012-11-06T10:46:33Z + +[Term] +id: GO:0097412 +name: hyaline inclusion +namespace: cellular_component +def: "A glass-like, pale intracellular inclusion." [NIF_Subcellular:nlx_subcell_20090104] +synonym: "pale body" RELATED [] +xref: NIF_Subcellular:nlx_subcell_20090104 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T16:24:58Z + +[Term] +id: GO:0097413 +name: Lewy body +namespace: cellular_component +def: "Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein." [NIF_Subcellular:sao4933778419] +synonym: "cytoplasmic inclusion" RELATED [] +xref: NIF_Subcellular:sao4933778419 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T16:26:08Z + +[Term] +id: GO:0097414 +name: classical Lewy body +namespace: cellular_component +def: "Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils." [NIF_Subcellular:sao4749542545] +synonym: "brainstem Lewy body" RELATED [] +xref: NIF_Subcellular:sao4749542545 +is_a: GO:0097413 ! Lewy body +created_by: pr +creation_date: 2012-11-06T16:27:41Z + +[Term] +id: GO:0097415 +name: cortical Lewy body +namespace: cellular_component +def: "Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils." [NIF_Subcellular:sao4040591221] +xref: NIF_Subcellular:sao4040591221 +is_a: GO:0097413 ! Lewy body +created_by: pr +creation_date: 2012-11-06T16:29:11Z + +[Term] +id: GO:0097416 +name: Lewy body-like hyaline inclusion +namespace: cellular_component +def: "Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments." [NIF_Subcellular:nlx_subcell_20090105, PMID:18026741] +synonym: "LBHI" EXACT [] +xref: NIF_Subcellular:nlx_subcell_20090105 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T16:46:15Z + +[Term] +id: GO:0097417 +name: nematosome +namespace: cellular_component +def: "Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles." [NIF_Subcellular:sao138430598, PMID:5458990] +xref: NIF_Subcellular:sao138430598 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T16:47:56Z + +[Term] +id: GO:0097418 +name: neurofibrillary tangle +namespace: cellular_component +def: "Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star." [NIF_Subcellular:nlx_subcell_20090201, NIF_Subcellular:nlx_subcell_20090202, NIF_Subcellular:sao2409833926] +comment: Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267). +synonym: "flame-shaped neurofibrillary tangle" NARROW [] +synonym: "star-shaped neurofibrillary tangle" NARROW [] +xref: NIF_Subcellular:nlx_subcell_20090201 +xref: NIF_Subcellular:nlx_subcell_20090202 +xref: NIF_Subcellular:sao2409833926 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T16:49:35Z + +[Term] +id: GO:0097419 +name: Pick body +namespace: cellular_component +def: "Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E." [NIF_Subcellular:nlx_subcell_20090102] +xref: NIF_Subcellular:nlx_subcell_20090102 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T20:57:02Z + +[Term] +id: GO:0097420 +name: skein-like inclusion +namespace: cellular_component +def: "Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin." [NIF_Subcellular:nlx_subcell_20090103, PMID:18026741] +xref: NIF_Subcellular:nlx_subcell_20090103 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-11-06T20:58:35Z + +[Term] +id: GO:0097421 +name: liver regeneration +namespace: biological_process +def: "The regrowth of lost or destroyed liver." [GOC:gap, PMID:19447520] +is_a: GO:0001889 ! liver development +is_a: GO:0031100 ! animal organ regeneration +created_by: pr +creation_date: 2012-11-07T10:22:43Z + +[Term] +id: GO:0097422 +name: tubular endosome +namespace: cellular_component +def: "A network of fine tubules in the vicinity of the Golgi complex and around the centriole." [NIF_Subcellular:sao1570660411, NIF_Subcellular:sao694815499, PMID:11896161] +synonym: "coated tip" RELATED [] +xref: NIF_Subcellular:sao1570660411 +xref: NIF_Subcellular:sao694815499 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005768 ! endosome +created_by: pr +creation_date: 2012-11-07T13:36:26Z + +[Term] +id: GO:0097423 +name: mitochondrion-associated adherens complex +namespace: cellular_component +def: "An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans." [NIF_Subcellular:sao1933817066, PMID:20089910] +synonym: "MAC" RELATED [] +synonym: "mitochondrial adhaerens complex" EXACT [] +xref: NIF_Subcellular:sao1933817066 +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005739 ! mitochondrion +relationship: has_part GO:0005911 ! cell-cell junction +created_by: pr +creation_date: 2012-11-07T13:38:50Z + +[Term] +id: GO:0097424 +name: nucleolus-associated heterochromatin +namespace: cellular_component +def: "Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus." [NIF_Subcellular:sao1210952635] +xref: NIF_Subcellular:sao1210952635 +is_a: GO:0030874 ! nucleolar chromatin +created_by: pr +creation_date: 2012-11-07T13:43:17Z + +[Term] +id: GO:0097425 +name: obsolete smooth endoplasmic reticulum part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER)." [NIF_Subcellular:sao184202831] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +synonym: "SER subcomponent" RELATED [NIF_Subcellular:sao1842028314] +xref: NIF_Subcellular:sao184202831 +is_obsolete: true +consider: GO:0005790 +created_by: pr +creation_date: 2012-11-07T13:45:14Z + +[Term] +id: GO:0097426 +name: glial filament +namespace: cellular_component +def: "An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes." [NIF_Subcellular:sao1863852493] +xref: NIF_Subcellular:sao1863852493 +is_a: GO:0005882 ! intermediate filament +created_by: pr +creation_date: 2012-11-07T14:59:55Z + +[Term] +id: GO:0097427 +name: microtubule bundle +namespace: cellular_component +def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973] +synonym: "microtubule fascicle" EXACT [] +xref: NIF_Subcellular:sao1872343973 +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005874 ! microtubule +relationship: part_of GO:0005856 ! cytoskeleton +created_by: pr +creation_date: 2012-11-07T15:01:27Z + +[Term] +id: GO:0097428 +name: protein maturation by iron-sulfur cluster transfer +namespace: biological_process +def: "The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein." [GOC:al, GOC:mah, PMID:11939799, PMID:18322036, PMID:21977977] +is_a: GO:0051604 ! protein maturation +created_by: pr +creation_date: 2012-11-15T09:59:06Z + +[Term] +id: GO:0097429 +name: amino acid ligation activity by nonribosomal peptide synthase +namespace: molecular_function +def: "Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase." [GOC:vw] +is_a: GO:0016881 ! acid-amino acid ligase activity +relationship: part_of GO:0019184 ! nonribosomal peptide biosynthetic process +created_by: pr +creation_date: 2012-11-16T12:34:22Z + +[Term] +id: GO:0097430 +name: copper ion import across prospore membrane +namespace: biological_process +def: "The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol." [GOC:al, GOC:vw, PMID:21828039] +synonym: "copper ion import across prospore membrane" EXACT [] +synonym: "copper ion import into ascospore-type prospore" RELATED [] +synonym: "copper ion transport into forespores" RELATED [] +is_a: GO:0015677 ! copper ion import +is_a: GO:0035434 ! copper ion transmembrane transport +created_by: pr +creation_date: 2012-11-16T12:37:05Z + +[Term] +id: GO:0097431 +name: mitotic spindle pole +namespace: cellular_component +def: "Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules." [GOC:vw] +is_a: GO:0000922 ! spindle pole +relationship: part_of GO:0072686 ! mitotic spindle +created_by: pr +creation_date: 2012-11-20T09:03:16Z + +[Term] +id: GO:0097432 +name: hippocampal pyramidal neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus." [CL:1001571, GOC:jc, PMID:19342486] +is_a: GO:1905270 ! Meynert cell differentiation +created_by: pr +creation_date: 2012-11-22T09:33:31Z + +[Term] +id: GO:0097433 +name: dense body +namespace: cellular_component +def: "An electron dense body which may contain granules." [ISBN:0195065719, NIF_Subcellular:sao730872736] +xref: NIF_Subcellular:sao730872736 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: pr +creation_date: 2012-11-22T15:34:04Z + +[Term] +id: GO:0097434 +name: succinate:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in)." [GOC:al, PMID:1293882] +synonym: "succinate:hydrogen symporter activity" EXACT [] +is_a: GO:0015141 ! succinate transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +created_by: pr +creation_date: 2012-11-26T18:19:42Z + +[Term] +id: GO:0097435 +name: supramolecular fiber organization +namespace: biological_process +alt_id: GO:0043206 +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr] +synonym: "extracellular fibril organisation" NARROW [] +synonym: "extracellular fibril organization" NARROW [] +synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah] +synonym: "fibril organisation" RELATED [] +synonym: "fibril organization" RELATED [] +is_a: GO:0016043 ! cellular component organization +created_by: pr +creation_date: 2012-11-27T15:46:25Z + +[Term] +id: GO:0097436 +name: entry into dormancy +namespace: biological_process +def: "The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated." [GOC:PO_curators, PO_REF:00009] +synonym: "induction of dormancy" EXACT [] +is_a: GO:0022611 ! dormancy process +created_by: pr +creation_date: 2012-12-05T14:55:49Z + +[Term] +id: GO:0097437 +name: maintenance of dormancy +namespace: biological_process +def: "The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated." [GOC:PO_curators, PO_REF:00009] +is_a: GO:0022611 ! dormancy process +created_by: pr +creation_date: 2012-12-05T15:00:24Z + +[Term] +id: GO:0097438 +name: exit from dormancy +namespace: biological_process +def: "The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated." [GOC:PO_curators, PO_REF:00009] +synonym: "release from dormancy" EXACT [] +is_a: GO:0022611 ! dormancy process +created_by: pr +creation_date: 2012-12-05T15:01:24Z + +[Term] +id: GO:0097439 +name: acquisition of desiccation tolerance +namespace: biological_process +def: "The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state." [GOC:PO_curators] +is_a: GO:0022611 ! dormancy process +created_by: pr +creation_date: 2012-12-05T15:09:52Z + +[Term] +id: GO:0097440 +name: apical dendrite +namespace: cellular_component +def: "A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon." [NIF_Subcellular:sao273773228] +xref: NIF_Subcellular:sao273773228 +is_a: GO:0030425 ! dendrite +created_by: pr +creation_date: 2012-12-06T13:45:18Z + +[Term] +id: GO:0097441 +name: basal dendrite +namespace: cellular_component +def: "A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon." [GOC:aruk, GOC:bc, NIF_Subcellular:sao1079900774, PMID:17046728, PMID:22683681] +synonym: "basilar dendrite" EXACT [NIF_Subcellular:sao1079900774] +xref: NIF_Subcellular:sao1079900774 +is_a: GO:0030425 ! dendrite +created_by: pr +creation_date: 2012-12-06T13:46:28Z + +[Term] +id: GO:0097442 +name: CA3 pyramidal cell dendrite +namespace: cellular_component +def: "A dendrite of a hippocampal CA3 pyramidal cell." [NIF_Subcellular:nlx_subcell_1005001] +xref: NIF_Subcellular:nlx_subcell_1005001 +is_a: GO:0030425 ! dendrite +created_by: pr +creation_date: 2012-12-06T13:47:23Z + +[Term] +id: GO:0097443 +name: sorting endosome +namespace: cellular_component +def: "A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles." [NIF_Subcellular:sao1028571114] +synonym: "MVB-tubule complex" RELATED [] +xref: NIF_Subcellular:sao1028571114 +is_a: GO:0005768 ! endosome +created_by: pr +creation_date: 2012-12-06T14:04:14Z + +[Term] +id: GO:0097444 +name: spine apparatus +namespace: cellular_component +def: "A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum." [NIF_Subcellular:sao725931194, PMID:20400711, PMID:8987748] +subset: goslim_synapse +synonym: "dense material" NARROW [NIF_Subcellular:sao1004601938] +xref: NIF_Subcellular:sao725931194 +is_a: GO:0043227 ! membrane-bounded organelle +relationship: part_of GO:0012505 ! endomembrane system +relationship: part_of GO:0043197 ! dendritic spine +created_by: pr +creation_date: 2012-12-06T14:05:58Z + +[Term] +id: GO:0097445 +name: presynaptic active zone dense projection +namespace: cellular_component +def: "Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered." [NIF_Subcellular:sao494258938, PMID:15381754] +synonym: "active zone dense projection" EXACT [] +synonym: "pre-synaptic active zone dense projection" EXACT [] +xref: NIF_Subcellular:sao494258938 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0048786 ! presynaptic active zone +created_by: pr +creation_date: 2012-12-06T14:08:21Z + +[Term] +id: GO:0097446 +name: protein localization to eisosome filament +namespace: biological_process +def: "A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1." [GOC:mah, GOC:vw, PMID:22869600, PMID:23722945] +synonym: "protein localization to linear eisosome" EXACT [] +is_a: GO:0044380 ! protein localization to cytoskeleton +is_a: GO:0072697 ! protein localization to cell cortex +created_by: pr +creation_date: 2012-12-17T09:37:49Z + +[Term] +id: GO:0097447 +name: dendritic tree +namespace: cellular_component +def: "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches." [GOC:aruk, GOC:bc, NIF_Subcellular:sao172297168] +xref: NIF_Subcellular:sao172297168 +is_a: GO:0043005 ! neuron projection +relationship: has_part GO:0030425 ! dendrite +relationship: part_of GO:0036477 ! somatodendritic compartment +created_by: pr +creation_date: 2012-12-17T12:31:49Z + +[Term] +id: GO:0097448 +name: spine mat +namespace: cellular_component +def: "A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma." [NIF_Subcellular:sao2128156969, PMID:10818137] +xref: NIF_Subcellular:sao2128156969 +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0044309 ! neuron spine +created_by: pr +creation_date: 2012-12-17T12:34:16Z + +[Term] +id: GO:0097449 +name: astrocyte projection +namespace: cellular_component +def: "A prolongation or process extending from the soma of an astrocyte and wrapping around neurons." [NIF_Subcellular:sao1630537580] +synonym: "astrocyte process" EXACT [] +synonym: "peripheral astrocyte process" RELATED [NIF_Subcellular:sao1573004591, PMID:12445894] +synonym: "vellous process" RELATED [NIF_Subcellular:sao1189060993] +xref: NIF_Subcellular:sao1630537580 +is_a: GO:0097386 ! glial cell projection +created_by: pr +creation_date: 2012-12-17T13:29:55Z + +[Term] +id: GO:0097450 +name: astrocyte end-foot +namespace: cellular_component +def: "Terminal process of astrocyte abutting non-neuronal surfaces in the brain." [NIF_Subcellular:sao388182739] +synonym: "astrocyte endfoot" EXACT [] +xref: NIF_Subcellular:sao388182739 +is_a: GO:0097449 ! astrocyte projection +created_by: pr +creation_date: 2012-12-17T13:33:55Z + +[Term] +id: GO:0097451 +name: glial limiting end-foot +namespace: cellular_component +def: "Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans." [NIF_Subcellular:sao181458425] +synonym: "glial limiting endfoot" EXACT [] +xref: NIF_Subcellular:sao181458425 +is_a: GO:0097450 ! astrocyte end-foot +created_by: pr +creation_date: 2012-12-17T13:36:34Z + +[Term] +id: GO:0097452 +name: GAIT complex +namespace: cellular_component +def: "A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP." [GOC:br, PMID:15479637, PMID:23071094] +synonym: "gamma interferon-activated inhibitor of translation complex" EXACT [] +synonym: "IFN-gamma-activated inhibitor of translation complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2012-12-19T09:32:25Z + +[Term] +id: GO:0097453 +name: mesaxon +namespace: cellular_component +def: "Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide." [ISBN:0195065719, NIF_Subcellular:sao2127666702] +synonym: "mesaxon of Schwann cell" NARROW [] +xref: NIF_Subcellular:sao2127666702 +is_a: GO:1990015 ! ensheathing process +created_by: pr +creation_date: 2012-12-19T12:59:13Z + +[Term] +id: GO:0097454 +name: Schwann cell microvillus +namespace: cellular_component +def: "Small finger-like extension of a Schwann cell that contacts the nodal membrane." [NIF_Subcellular:sao1890444066, PMID:15988042] +xref: NIF_Subcellular:sao1890444066 +is_a: GO:0005902 ! microvillus +is_a: GO:0097386 ! glial cell projection +created_by: pr +creation_date: 2012-12-19T13:01:02Z + +[Term] +id: GO:0097455 +name: spiny bracelet of Nageotte +namespace: cellular_component +def: "Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin." [NIF_Subcellular:sao937871668, PMID:15988042] +xref: NIF_Subcellular:sao937871668 +is_a: GO:0097386 ! glial cell projection +created_by: pr +creation_date: 2012-12-19T13:02:33Z + +[Term] +id: GO:0097456 +name: terminal loop +namespace: cellular_component +def: "Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath." [NIF_Subcellular:sao924713546] +synonym: "terminal loop of Schwann cell" EXACT [] +xref: NIF_Subcellular:sao924713546 +is_a: GO:0097386 ! glial cell projection +created_by: pr +creation_date: 2012-12-19T13:04:06Z + +[Term] +id: GO:0097457 +name: hippocampal mossy fiber +namespace: cellular_component +def: "Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal." [NIF_Subcellular:nlx_subcell_100312, PMID:17765709] +xref: NIF_Subcellular:nlx_subcell_100312 +is_a: GO:0044302 ! dentate gyrus mossy fiber +created_by: pr +creation_date: 2012-12-19T16:51:57Z + +[Term] +id: GO:0097458 +name: obsolete neuron part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [GOC:pr, Wikipedia:Neuron] +subset: gocheck_do_not_annotate +subset: goslim_flybase_ribbon +is_obsolete: true +consider: CL:0000540 +created_by: pr +creation_date: 2012-12-19T16:53:50Z + +[Term] +id: GO:0097462 +name: Lewy neurite +namespace: cellular_component +def: "Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease." [NIF_Subcellular:sao601362597] +xref: NIF_Subcellular:sao601362597 +is_a: GO:0043005 ! neuron projection +created_by: pr +creation_date: 2012-12-21T07:57:58Z + +[Term] +id: GO:0097463 +name: gemmule +namespace: cellular_component +def: "Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex." [NIF_Subcellular:nlx_subcell_1005003] +xref: NIF_Subcellular:nlx_subcell_1005003 +is_a: GO:0043005 ! neuron projection +created_by: pr +creation_date: 2012-12-21T07:59:04Z + +[Term] +id: GO:0097464 +name: thorny excrescence +namespace: cellular_component +def: "Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads." [NIF_Subcellular:nlx_467, PMID:730852] +xref: NIF_Subcellular:nlx_467 +is_a: GO:0043197 ! dendritic spine +created_by: pr +creation_date: 2012-12-21T08:00:13Z + +[Term] +id: GO:0097465 +name: somatic spine +namespace: cellular_component +def: "Spine emanating from the cell soma of a neuron." [NIF_Subcellular:sao2048514053] +xref: NIF_Subcellular:sao2048514053 +is_a: GO:0044309 ! neuron spine +created_by: pr +creation_date: 2012-12-21T08:02:37Z + +[Term] +id: GO:0097466 +name: ubiquitin-dependent glycoprotein ERAD pathway +namespace: biological_process +def: "An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component." [GOC:al, GOC:bf, PMID:16079177] +synonym: "ER-associated glycoprotein degradation" EXACT [GOC:bf] +synonym: "glycoprotein ERAD" EXACT [GOC:bf] +synonym: "gpERAD" EXACT [PMID:25092655] +synonym: "misfolded or incompletely synthesized glycoprotein catabolic process" BROAD [] +is_a: GO:0006516 ! glycoprotein catabolic process +is_a: GO:0030433 ! ubiquitin-dependent ERAD pathway +is_a: GO:1904587 ! response to glycoprotein +created_by: pr +creation_date: 2013-02-05T16:37:13Z + +[Term] +id: GO:0097467 +name: type III terminal bouton +namespace: cellular_component +def: "Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones." [GOC:mc, PMID:10218156] +synonym: "type III terminal button" EXACT [] +is_a: GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2013-02-06T09:39:18Z + +[Term] +id: GO:0097468 +name: programmed cell death in response to reactive oxygen species +namespace: biological_process +def: "Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:mtg_apoptosis] +synonym: "PCD in response to oxidative stress" BROAD [] +synonym: "PCD in response to reactive oxygen species" EXACT [] +synonym: "programmed cell death in response to oxidative stress" BROAD [] +synonym: "reactive oxygen species-mediated PCD" EXACT [] +synonym: "reactive oxygen species-mediated programmed cell death" EXACT [] +is_a: GO:0012501 ! programmed cell death +is_a: GO:0036473 ! cell death in response to oxidative stress +relationship: part_of GO:0034614 ! cellular response to reactive oxygen species +created_by: pr +creation_date: 2013-02-19T10:03:36Z + +[Term] +id: GO:0097469 +name: obsolete cyclin-dependent protein tyrosine kinase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit." [GOC:al, GOC:vw, PMID:1372994] +comment: This term was made obsolete because it was added in error; the specific activity it refers to has never been observed. +synonym: "cyclin-dependent protein tyrosine kinase activity" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2013-02-19T12:42:11Z + +[Term] +id: GO:0097470 +name: ribbon synapse +namespace: cellular_component +def: "Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm." [NIF_Subcellular:sao1884931180, PMID:15626493] +synonym: "synapsis fasciolaris" EXACT [Wikipedia:Ribbon_synapse&oldid=757407851] +xref: NIF_Subcellular:sao1884931180 +is_a: GO:0045202 ! synapse +intersection_of: GO:0045202 ! synapse +intersection_of: has_part GO:0098681 ! synaptic ribbon +relationship: has_part GO:0098681 ! synaptic ribbon +created_by: pr +creation_date: 2013-02-21T07:40:01Z + +[Term] +id: GO:0097471 +name: mossy fiber rosette +namespace: cellular_component +def: "A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes." [NIF_Subcellular:nlx_subcell_091021, Wikipedia:Mossy_fiber_(cerebellum)] +subset: goslim_synapse +synonym: "cerebellar mossy fiber to granule cell synapse" EXACT syngo_official_label [] +xref: NIF_Subcellular:nlx_subcell_091021 +is_a: GO:0032279 ! asymmetric synapse +created_by: pr +creation_date: 2013-02-21T07:42:52Z + +[Term] +id: GO:0097472 +name: cyclin-dependent protein kinase activity +namespace: molecular_function +def: "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)." [GOC:pr] +is_a: GO:0004672 ! protein kinase activity +relationship: has_part GO:0030332 ! cyclin binding +relationship: part_of GO:0051726 ! regulation of cell cycle +created_by: pr +creation_date: 2013-03-06T13:46:04Z + +[Term] +id: GO:0097473 +name: retinal rod cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487] +synonym: "rod photoreceptor apoptotic process" EXACT [] +is_a: GO:0051402 ! neuron apoptotic process +is_a: GO:1990009 ! retinal cell apoptotic process +created_by: pr +creation_date: 2013-03-21T09:44:45Z + +[Term] +id: GO:0097474 +name: retinal cone cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc] +synonym: "cone photoreceptor apoptotic process" EXACT [] +is_a: GO:0051402 ! neuron apoptotic process +is_a: GO:1990009 ! retinal cell apoptotic process +created_by: pr +creation_date: 2013-03-21T09:46:22Z + +[Term] +id: GO:0097475 +name: motor neuron migration +namespace: biological_process +def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475] +is_a: GO:0001764 ! neuron migration +created_by: pr +creation_date: 2013-04-23T13:00:46Z + +[Term] +id: GO:0097476 +name: spinal cord motor neuron migration +namespace: biological_process +def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475] +is_a: GO:0097475 ! motor neuron migration +created_by: pr +creation_date: 2013-04-23T13:03:46Z + +[Term] +id: GO:0097477 +name: lateral motor column neuron migration +namespace: biological_process +def: "The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme." [CL:0011002, GOC:yaf, PMID:20711475] +is_a: GO:0097476 ! spinal cord motor neuron migration +created_by: pr +creation_date: 2013-04-23T13:05:32Z + +[Term] +id: GO:0097478 +name: leaflet of membrane bilayer +namespace: cellular_component +def: "Any of the two layers of lipid molecules that constitute a membrane." [GOC:cjm] +synonym: "membrane leaflet" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0016020 ! membrane +created_by: pr +creation_date: 2013-05-07T14:24:37Z + +[Term] +id: GO:0097479 +name: synaptic vesicle localization +namespace: biological_process +def: "Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:pr] +synonym: "establishment and maintenance of synaptic vesicle localization" EXACT [] +synonym: "establishment and maintenance of synaptic vesicle position" EXACT [] +synonym: "synaptic vesicle localisation" EXACT [] +is_a: GO:0051648 ! vesicle localization +created_by: pr +creation_date: 2013-05-22T14:29:55Z + +[Term] +id: GO:0097480 +name: establishment of synaptic vesicle localization +namespace: biological_process +def: "The directed movement of a synaptic vesicle or vesicles to a specific location." [GOC:pr] +synonym: "establishment of synaptic vesicle localisation" EXACT [] +is_a: GO:0051650 ! establishment of vesicle localization +relationship: part_of GO:0097479 ! synaptic vesicle localization +created_by: pr +creation_date: 2013-05-22T14:32:12Z + +[Term] +id: GO:0097482 +name: muscle cell postsynaptic specialization +namespace: cellular_component +def: "A postsynaptic specialization that is part of a neuromuscular junction." [GOC:pr] +synonym: "muscle cell postsynaptic density" EXACT [] +synonym: "muscle fiber postsynaptic density" EXACT [] +is_a: GO:0099572 ! postsynaptic specialization +intersection_of: GO:0099572 ! postsynaptic specialization +intersection_of: part_of GO:0098975 ! postsynapse of neuromuscular junction +relationship: part_of GO:0098975 ! postsynapse of neuromuscular junction +created_by: pr +creation_date: 2013-07-02T09:47:40Z + +[Term] +id: GO:0097484 +name: dendrite extension +namespace: biological_process +def: "Long distance growth of a single dendrite involved in cellular development." [GOC:BHF, GOC:rl] +is_a: GO:1990138 ! neuron projection extension +created_by: pr +creation_date: 2013-07-08T09:52:31Z + +[Term] +id: GO:0097485 +name: neuron projection guidance +namespace: biological_process +def: "The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues." [GOC:BHF, GOC:rl, PMID:22790009] +synonym: "neurite guidance" NARROW [] +synonym: "neuron process guidance" EXACT [] +synonym: "neuron protrusion guidance" EXACT [] +synonym: "neuronal cell projection guidance" EXACT [] +is_a: GO:0006928 ! movement of cell or subcellular component +relationship: part_of GO:0006935 ! chemotaxis +relationship: part_of GO:0048812 ! neuron projection morphogenesis +created_by: pr +creation_date: 2013-07-08T13:32:37Z + +[Term] +id: GO:0097486 +name: multivesicular body lumen +namespace: cellular_component +def: "The volume enclosed by the outermost membrane of a multivesicular body." [GOC:pde, PMID:21183070] +is_a: GO:0031906 ! late endosome lumen +relationship: part_of GO:0005771 ! multivesicular body +created_by: pr +creation_date: 2013-07-08T20:32:56Z + +[Term] +id: GO:0097487 +name: multivesicular body, internal vesicle +namespace: cellular_component +def: "A membrane-bounded vesicle wholly contained within a multivesicular body." [GOC:pde, PMID:21183070] +is_a: GO:0031410 ! cytoplasmic vesicle +relationship: part_of GO:0005771 ! multivesicular body +created_by: pr +creation_date: 2013-07-08T20:34:51Z + +[Term] +id: GO:0097488 +name: multivesicular body, internal vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a multivesicular body internal vesicle." [GOC:pde, PMID:21183070] +is_a: GO:0012506 ! vesicle membrane +is_a: GO:0098588 ! bounding membrane of organelle +relationship: part_of GO:0097487 ! multivesicular body, internal vesicle +created_by: pr +creation_date: 2013-07-08T20:36:33Z + +[Term] +id: GO:0097489 +name: multivesicular body, internal vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of the multivesicular body internal vesicle." [GOC:pde, PMID:21183070] +is_a: GO:0031983 ! vesicle lumen +is_a: GO:0070013 ! intracellular organelle lumen +relationship: part_of GO:0097487 ! multivesicular body, internal vesicle +created_by: pr +creation_date: 2013-07-08T20:38:36Z + +[Term] +id: GO:0097490 +name: sympathetic neuron projection extension +namespace: biological_process +def: "Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:BHF, GOC:rl, PMID:22790009] +synonym: "sympathetic neurite extension" NARROW [] +synonym: "sympathetic neuron process extension" EXACT [] +synonym: "sympathetic neuron protrusion extension" EXACT [] +synonym: "sympathetic neuronal cell projection extension" EXACT [] +is_a: GO:1990138 ! neuron projection extension +created_by: pr +creation_date: 2013-07-10T11:47:53Z + +[Term] +id: GO:0097491 +name: sympathetic neuron projection guidance +namespace: biological_process +def: "The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues." [GOC:BHF, GOC:rl, PMID:22790009] +synonym: "sympathetic neurite guidance" NARROW [] +synonym: "sympathetic neuron process guidance" EXACT [] +synonym: "sympathetic neuron protrusion guidance" EXACT [] +synonym: "sympathetic neuronal cell projection guidance" EXACT [] +is_a: GO:0097485 ! neuron projection guidance +created_by: pr +creation_date: 2013-07-10T11:49:21Z + +[Term] +id: GO:0097492 +name: sympathetic neuron axon guidance +namespace: biological_process +def: "The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." [GOC:BHF, GOC:rl, PMID:22790009] +synonym: "sympathetic neuron axon chemotaxis" RELATED [] +synonym: "sympathetic neuron axon growth cone guidance" NARROW [] +synonym: "sympathetic neuron axon pathfinding" EXACT [] +is_a: GO:0007411 ! axon guidance +created_by: pr +creation_date: 2013-07-10T11:50:52Z + +[Term] +id: GO:0097493 +name: structural molecule activity conferring elasticity +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling." [GOC:BHF, GOC:rl, PMID:23283722] +is_a: GO:0005198 ! structural molecule activity +created_by: pr +creation_date: 2013-07-26T09:47:26Z + +[Term] +id: GO:0097494 +name: regulation of vesicle size +namespace: biological_process +def: "Any process that modulates the size of a vesicle." [GOC:pm, PMID:20007772] +is_a: GO:0032535 ! regulation of cellular component size +created_by: pr +creation_date: 2013-08-06T11:48:51Z + +[Term] +id: GO:0097495 +name: H-NS-Hha complex +namespace: cellular_component +def: "A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes." [GOC:bhm, PMID:21600204] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990121 ! H-NS complex +relationship: part_of GO:0005829 ! cytosol +created_by: pr +creation_date: 2013-08-08T14:37:33Z + +[Term] +id: GO:0097496 +name: blood vessel lumen ensheathment +namespace: biological_process +def: "A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel." [GOC:dgh, PMID:23698350] +is_a: GO:0072554 ! blood vessel lumenization +created_by: pr +creation_date: 2013-08-12T13:46:45Z + +[Term] +id: GO:0097497 +name: blood vessel endothelial cell delamination +namespace: biological_process +def: "The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet." [GOC:dgh, PMID:23698350] +is_a: GO:0060232 ! delamination +created_by: pr +creation_date: 2013-08-12T13:48:34Z + +[Term] +id: GO:0097498 +name: endothelial tube lumen extension +namespace: biological_process +def: "Any endothelial tube morphogenesis process by which the tube is increased in length." [GOC:dgh, PMID:23698350] +is_a: GO:0061154 ! endothelial tube morphogenesis +created_by: pr +creation_date: 2013-08-12T13:49:54Z + +[Term] +id: GO:0097499 +name: protein localization to non-motile cilium +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a non-motile cilium." [GOC:cilia, GOC:kmv, PMID:23128241] +synonym: "protein localization to nonmotile primary cilium" RELATED [] +is_a: GO:0061512 ! protein localization to cilium +created_by: pr +creation_date: 2013-08-13T12:16:26Z + +[Term] +id: GO:0097500 +name: receptor localization to non-motile cilium +namespace: biological_process +def: "A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium." [GOC:cilia, GOC:kmv, PMID:23128241] +synonym: "receptor localization to nonmotile primary cilium" RELATED [] +is_a: GO:0097499 ! protein localization to non-motile cilium +is_a: GO:1903441 ! protein localization to ciliary membrane +created_by: pr +creation_date: 2013-08-13T12:17:34Z + +[Term] +id: GO:0097501 +name: stress response to metal ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus." [GOC:kmv] +synonym: "response to excess metal ion" RELATED [] +synonym: "response to metal ion stress" EXACT [] +synonym: "response to metal ion toxicity" RELATED [] +synonym: "response to metal toxicity" RELATED [] +is_a: GO:0006950 ! response to stress +is_a: GO:0010038 ! response to metal ion +created_by: pr +creation_date: 2013-08-15T10:37:45Z + +[Term] +id: GO:0097502 +name: mannosylation +namespace: biological_process +def: "The covalent attachment of a mannose residue to a substrate molecule." [GOC:cjm] +is_a: GO:0070085 ! glycosylation +created_by: pr +creation_date: 2013-09-20T09:47:40Z + +[Term] +id: GO:0097503 +name: sialylation +namespace: biological_process +def: "The covalent attachment of sialic acid to a substrate molecule." [GOC:cjm] +is_a: GO:0043412 ! macromolecule modification +created_by: pr +creation_date: 2013-09-20T09:53:10Z + +[Term] +id: GO:0097504 +name: Gemini of coiled bodies +namespace: cellular_component +def: "Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA)." [GOC:pr, PMID:11031238, PMID:9683623, Wikipedia:Cell_nucleus#Cajal_bodies_and_gems] +synonym: "Gems" EXACT [] +is_a: GO:0016604 ! nuclear body +created_by: pr +creation_date: 2013-09-24T15:20:12Z + +[Term] +id: GO:0097505 +name: Rad6-Rad18 complex +namespace: cellular_component +def: "A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity." [GOC:jd, PMID:9287349] +is_a: GO:0000151 ! ubiquitin ligase complex +created_by: pr +creation_date: 2013-09-26T13:42:58Z + +[Term] +id: GO:0097506 +name: deaminated base DNA N-glycosylase activity +namespace: molecular_function +def: "DNA N-glycosylase activity acting on deaminated bases." [GOC:al, PMID:18789404] +synonym: "deaminated base DNA glycosylase activity" EXACT [] +synonym: "DNA glycosylase activity acting on deaminated bases" EXACT [] +is_a: GO:0019104 ! DNA N-glycosylase activity +created_by: pr +creation_date: 2013-09-26T16:00:40Z + +[Term] +id: GO:0097507 +name: hypoxanthine DNA N-glycosylase activity +namespace: molecular_function +def: "DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine)." [GOC:al, PMID:18789404] +synonym: "hypoxanthine-DNA glycosylase activity" RELATED [] +is_a: GO:0097506 ! deaminated base DNA N-glycosylase activity +created_by: pr +creation_date: 2013-09-26T16:02:08Z + +[Term] +id: GO:0097508 +name: xanthine DNA N-glycosylase activity +namespace: molecular_function +def: "DNA N-glycosylase activity acting on deaminated guanine (xanthine)." [GOC:al, PMID:18789404] +synonym: "xanthine-DNA glycosylase activity" RELATED [] +is_a: GO:0097506 ! deaminated base DNA N-glycosylase activity +created_by: pr +creation_date: 2013-09-26T16:03:10Z + +[Term] +id: GO:0097509 +name: oxanine DNA N-glycosylase activity +namespace: molecular_function +def: "DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination." [GOC:al, PMID:18789404] +synonym: "oxanine-DNA glycosylase activity" RELATED [] +is_a: GO:0097506 ! deaminated base DNA N-glycosylase activity +created_by: pr +creation_date: 2013-09-26T16:03:58Z + +[Term] +id: GO:0097510 +name: base-excision repair, AP site formation via deaminated base removal +namespace: biological_process +def: "A base-excision repair, AP site formation process occurring via excision of a deaminated base." [GOC:al, PMID:18789404] +is_a: GO:0006285 ! base-excision repair, AP site formation +relationship: has_part GO:0097506 ! deaminated base DNA N-glycosylase activity +created_by: pr +creation_date: 2013-10-08T14:44:01Z + +[Term] +id: GO:0097511 +name: dendritic cell dendrite +namespace: cellular_component +def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351] +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: pr +creation_date: 2013-10-16T13:02:25Z + +[Term] +id: GO:0097512 +name: cardiac myofibril +namespace: cellular_component +def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol] +is_a: GO:0030016 ! myofibril +created_by: pr +creation_date: 2013-10-16T13:04:58Z + +[Term] +id: GO:0097513 +name: myosin II filament +namespace: cellular_component +def: "A bipolar filament composed of myosin II molecules." [GOC:cjm, GOC:mah] +is_a: GO:0032982 ! myosin filament +created_by: pr +creation_date: 2013-10-16T13:06:20Z + +[Term] +id: GO:0097514 +name: sexual spore wall +namespace: cellular_component +def: "A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis." [GOC:cjm, GOC:mah] +is_a: GO:0031160 ! spore wall +created_by: pr +creation_date: 2013-10-16T15:10:32Z + +[Term] +id: GO:0097515 +name: asexual spore wall +namespace: cellular_component +def: "A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species." [GOC:cjm, GOC:mah] +is_a: GO:0031160 ! spore wall +created_by: pr +creation_date: 2013-10-16T15:11:21Z + +[Term] +id: GO:0097516 +name: microvillar actin bundle +namespace: cellular_component +def: "A parallel bundle of actin filaments at the core of a microvillus." [GOC:cjm, GOC:mah] +is_a: GO:0098859 ! actin filament bundle of actin-based cell projection +intersection_of: GO:0097518 ! parallel actin filament bundle +intersection_of: part_of GO:0005902 ! microvillus +relationship: part_of GO:0005902 ! microvillus +created_by: pr +creation_date: 2013-10-16T15:12:13Z + +[Term] +id: GO:0097517 +name: contractile actin filament bundle +namespace: cellular_component +def: "An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle." [GOC:cjm, GOC:mah, ISBN:0815316194] +is_a: GO:0032432 ! actin filament bundle +disjoint_from: GO:0097518 ! parallel actin filament bundle +created_by: pr +creation_date: 2013-10-16T15:41:14Z + +[Term] +id: GO:0097518 +name: parallel actin filament bundle +namespace: cellular_component +def: "An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity." [GOC:cjm, GOC:mah, ISBN:0815316194] +is_a: GO:0032432 ! actin filament bundle +created_by: pr +creation_date: 2013-10-16T15:42:17Z + +[Term] +id: GO:0097519 +name: DNA recombinase complex +namespace: cellular_component +def: "A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA." [GOC:cjm, PMID:10357855] +is_a: GO:0032993 ! protein-DNA complex +created_by: pr +creation_date: 2013-10-16T15:43:22Z + +[Term] +id: GO:0097520 +name: nucleotide-excision repair, preincision complex +namespace: cellular_component +def: "A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage." [GOC:cjm, GOC:elh, PMID:10197977] +synonym: "UvrA(2)-UvrB(2) complex" NARROW [PMID:12145219] +synonym: "UvrA(2)B(2) complex" NARROW [GOC:bhm, PMID:12145219] +synonym: "UvrB dimer" NARROW [GOC:bhm, PMID:12145219] +is_a: GO:0032993 ! protein-DNA complex +created_by: pr +creation_date: 2013-10-17T14:32:37Z + +[Term] +id: GO:0097522 +name: protein-DNA ISRE complex +namespace: cellular_component +def: "A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA." [GOC:amm, GOC:cjm, PMID:11747630] +is_a: GO:0032993 ! protein-DNA complex +created_by: pr +creation_date: 2013-10-17T14:35:07Z + +[Term] +id: GO:0097523 +name: transcription ternary complex +namespace: cellular_component +def: "A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript." [GOC:cjm, GOC:txnOH] +synonym: "transcription protein-DNA-RNA complex" EXACT [] +is_a: GO:0001114 ! protein-DNA-RNA complex +created_by: pr +creation_date: 2013-10-18T11:29:57Z + +[Term] +id: GO:0097524 +name: sperm plasma membrane +namespace: cellular_component +def: "A plasma membrane that is part of a sperm cell." [GOC:cjm] +is_a: GO:0005886 ! plasma membrane +created_by: pr +creation_date: 2013-10-18T11:31:17Z + +[Term] +id: GO:0097525 +name: spliceosomal snRNP complex +namespace: cellular_component +def: "A ribonucleoprotein complex involved in formation of the spliceosome and composed of one or more snRNA and multiple protein components." [GOC:pr, ISBN:0879695897] +is_a: GO:0030532 ! small nuclear ribonucleoprotein complex +created_by: pr +creation_date: 2013-10-18T15:57:45Z + +[Term] +id: GO:0097526 +name: spliceosomal tri-snRNP complex +namespace: cellular_component +def: "A spliceosomal snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins." [GOC:pr, ISBN:0879695897, PMID:9452384] +is_a: GO:0097525 ! spliceosomal snRNP complex +created_by: pr +creation_date: 2013-10-18T15:58:47Z + +[Term] +id: GO:0097527 +name: necroptotic signaling pathway +namespace: biological_process +def: "A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered." [GOC:mtg_apoptosis, PMID:20823910] +comment: Gene products that may be annotated to this term include: 1) ligands such as TNF-alpha; 2) receptors such as TNFR (though care should be taken because TNF-alpha and TNFR may also be involved in non-necroptotic processes); 3) signaling molecules such as TNFR-associated death domain (TRADD), receptor-interacting protein kinase 1 (RIP1), cellular inhibitor of apoptosis 1 (cIAP1), cIAP2, TNFR-associated factor 2 (TRAF2) and TRAF5. Within the so-called complex I, RIP1 is polyubiquitinated by cIAPs, thereby providing a docking site for the recruitment of transforming growth factor beta (TGFbeta)-activated kinase 1 (TAK1), TAK1-binding protein 2 (TAB2) and TAB3 (which together deliver a pro-survival signal by activating the transcription factor NF-kB). In some pathophysiological and experimental settings, and in particular when caspase-8 is absent or when caspases are inhibited by pharmacological agents, cylindromatosis (CYLD)-deubiquitinated RIP1 engage in physical and functional interactions with its homolog RIP3, ultimately activating the execution of necrotic cell death. (The pathway downstream of RIPK3 remains largely unknown, although ROS generation, calcium overload, and the opening of the mitochondrial permeability transition pore have been implicated (PMID:22265414)). A necroptotic signaling pathway may also be induced by alkylating DNA damage (possibly by the overactivation of poly(ADP-ribose) polymerase 1, PARP1). This is sometimes referred to as PARP-dependent cell death or parthanatos; it is still being debated if it constitutes an independent cell death modality. +synonym: "necroptosis signaling" RELATED [] +synonym: "necroptosis signaling pathway" EXACT [] +synonym: "necroptotic signal transduction" EXACT [GOC:signaling] +synonym: "necroptotic signalling pathway" RELATED [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0070266 ! necroptotic process +created_by: pr +creation_date: 2013-11-05T14:17:28Z + +[Term] +id: GO:0097528 +name: execution phase of necroptosis +namespace: biological_process +def: "A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died." [GOC:mtg_apoptosis, PMID:20823910] +synonym: "execution phase of necroptotic process" EXACT [] +synonym: "necroptosis" BROAD [] +synonym: "necroptotic execution phase" EXACT [] +is_a: GO:0009987 ! cellular process +relationship: part_of GO:0070266 ! necroptotic process +created_by: pr +creation_date: 2013-11-05T14:23:53Z + +[Term] +id: GO:0097529 +name: myeloid leukocyte migration +namespace: biological_process +def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461] +is_a: GO:0050900 ! leukocyte migration +created_by: pr +creation_date: 2013-11-11T13:59:43Z + +[Term] +id: GO:0097530 +name: granulocyte migration +namespace: biological_process +def: "The movement of a granulocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:24163421, PMID:24193336] +is_a: GO:0097529 ! myeloid leukocyte migration +created_by: pr +creation_date: 2013-11-11T14:00:44Z + +[Term] +id: GO:0097531 +name: mast cell migration +namespace: biological_process +def: "The movement of a mast cell within or between different tissues and organs of the body." [GOC:cvs, PMID:24152847] +is_a: GO:0097529 ! myeloid leukocyte migration +created_by: pr +creation_date: 2013-11-11T14:01:41Z + +[Term] +id: GO:0097532 +name: stress response to acid chemical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:aa, GOC:BHF, GOC:go_curators, GOC:rl, PMID:10615049, PMID:19170886, Wikipedia:Acid] +synonym: "response to acid stress" BROAD [] +synonym: "stress response to acid" BROAD [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0006950 ! response to stress +created_by: pr +creation_date: 2013-11-12T13:04:15Z + +[Term] +id: GO:0097533 +name: cellular stress response to acid chemical +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:aa, GOC:BHF, GOC:go_curators, GOC:rl, PMID:10615049, PMID:19170886, Wikipedia:Acid] +synonym: "cellular response to acid stress" BROAD [] +synonym: "cellular stress response to acid" BROAD [] +is_a: GO:0097532 ! stress response to acid chemical +relationship: part_of GO:0033554 ! cellular response to stress +relationship: part_of GO:0071229 ! cellular response to acid chemical +created_by: pr +creation_date: 2013-11-12T13:07:12Z + +[Term] +id: GO:0097534 +name: lymphoid lineage cell migration +namespace: biological_process +def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843] +synonym: "lymphoid lineage restricted progenitor cell migration" EXACT [] +is_a: GO:0016477 ! cell migration +created_by: pr +creation_date: 2013-11-28T10:47:15Z + +[Term] +id: GO:0097535 +name: lymphoid lineage cell migration into thymus +namespace: biological_process +def: "The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process." [GOC:cvs, PMID:22342843] +synonym: "lymphoid lineage restricted progenitor cell migration into thymus" EXACT [] +is_a: GO:0097534 ! lymphoid lineage cell migration +created_by: pr +creation_date: 2013-11-28T10:48:58Z + +[Term] +id: GO:0097536 +name: thymus epithelium morphogenesis +namespace: biological_process +def: "The process in which the thymus epithelium is generated and organized." [GOC:pr, PMID:22342843] +synonym: "thymic epithelium morphogenesis" EXACT [] +is_a: GO:0002009 ! morphogenesis of an epithelium +relationship: part_of GO:0048538 ! thymus development +created_by: pr +creation_date: 2013-11-28T10:51:03Z + +[Term] +id: GO:0097537 +name: Y-shaped link +namespace: cellular_component +def: "A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium." [GOC:cilia, PMID:22653444, PMID:4554367] +synonym: "membrane-microtubule complex" RELATED [] +synonym: "Y-link" RELATED [] +synonym: "Y-link structure" RELATED [] +synonym: "Y-shaped assemblage" RELATED [] +synonym: "Y-shaped fiber" RELATED [] +synonym: "Y-shaped fibre" RELATED [] +synonym: "Y-shaped linker" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0035869 ! ciliary transition zone +created_by: pr +creation_date: 2013-12-03T16:34:34Z + +[Term] +id: GO:0097538 +name: ciliary necklace +namespace: cellular_component +def: "A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links." [GOC:cilia, PMID:22653444, PMID:4554367] +synonym: "cilial necklace" EXACT [] +synonym: "cilium necklace" EXACT [] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0035869 ! ciliary transition zone +relationship: part_of GO:0060170 ! ciliary membrane +created_by: pr +creation_date: 2013-12-03T16:43:41Z + +[Term] +id: GO:0097539 +name: ciliary transition fiber +namespace: cellular_component +def: "A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium)." [GOC:cilia, GOC:kmv, GOC:krc, PMID:22653444, PMID:24231678, PMID:5064817, PMID:5335827] +comment: In mammals, ciliary transition fibers comprise at least five components (Ccdc41/Cep83, Cep89/Cep123, Sclt1, Fbf1, and Cep164) (PMID:24469809). +synonym: "centriolar distal appendage" RELATED [PMID:24469809] +synonym: "cilial transition fiber" EXACT [] +synonym: "cilial transition fibre" EXACT [] +synonym: "ciliary transition fibre" EXACT [] +synonym: "cilium transition fiber" EXACT [] +synonym: "cilium transition fibre" EXACT [] +synonym: "distal appendage of basal body" RELATED [GOC:krc] +synonym: "distal appendage of centriole" RELATED [GOC:krc] +synonym: "distal appendage of mother centriole" RELATED [GOC:krc] +synonym: "transition fiber" BROAD [] +synonym: "transition fibre" BROAD [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2013-12-03T16:46:37Z + +[Term] +id: GO:0097540 +name: axonemal central pair +namespace: cellular_component +def: "Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia." [GOC:cilia, GOC:krc, PMID:24283352] +synonym: "axonemal microtubule central pair" EXACT [] +synonym: "axoneme central pair" EXACT [] +synonym: "axoneme microtubule central pair" EXACT [] +synonym: "central pair" BROAD [] +synonym: "central-pair microtubules" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:1990719 ! C1 axonemal microtubule +relationship: has_part GO:1990720 ! C2 axonemal microtubule +relationship: part_of GO:1990716 ! axonemal central apparatus +created_by: pr +creation_date: 2013-12-12T11:07:09Z + +[Term] +id: GO:0097541 +name: axonemal basal plate +namespace: cellular_component +def: "Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure." [GOC:cilia, PMID:23352055, PMID:4554367] +synonym: "axoneme basal plate" EXACT [] +synonym: "basal plate" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005930 ! axoneme +created_by: pr +creation_date: 2013-12-12T11:10:39Z + +[Term] +id: GO:0097542 +name: ciliary tip +namespace: cellular_component +def: "Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction." [GOC:cilia, PMID:23970417] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "cilial tip" EXACT [] +synonym: "cilium tip" EXACT [] +synonym: "flagellar tip" EXACT [] +synonym: "flagellum tip" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2013-12-12T11:12:22Z + +[Term] +id: GO:0097543 +name: ciliary inversin compartment +namespace: cellular_component +def: "Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium." [GOC:cilia, PMID:19050042] +comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "cilial inversin compartment" EXACT [] +synonym: "cilium inversin compartment" EXACT [] +synonym: "flagellar inversin compartment" EXACT [] +synonym: "flagellum inversin compartment" EXACT [] +synonym: "Inv compartment of the cilium" EXACT [] +synonym: "inversin compartment" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2013-12-12T11:14:36Z + +[Term] +id: GO:0097544 +name: ciliary shaft +namespace: cellular_component +def: "The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space." [GOC:cilia, GOC:krc, PMID:19866682] +comment: Note that 'ciliary shaft' is sparingly used in the literature to denote the projecting part of the cilium; many authors would refer to the axoneme instead. However, the definition of GO:0005930 'axoneme' is rather stringent, and the localization of many ciliary proteins would not fit that definition. Also, note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "cilial shaft" EXACT [] +synonym: "cilium shaft" EXACT [] +synonym: "flagellar shaft" EXACT [] +synonym: "flagellum shaft" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005930 ! axoneme +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2013-12-12T11:17:30Z + +[Term] +id: GO:0097545 +name: axonemal outer doublet +namespace: cellular_component +def: "Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium." [GOC:cilia, GOC:krc, GOC:pr, PMID:5044758, PMID:5664206, Wikipedia:Axoneme] +synonym: "axoneme outer doublet" EXACT [] +synonym: "outer doublet" BROAD [] +synonym: "outer-doublet microtubules" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097649 ! A axonemal microtubule +relationship: has_part GO:0097650 ! B axonemal microtubule +relationship: part_of GO:0005930 ! axoneme +created_by: pr +creation_date: 2013-12-12T11:19:29Z + +[Term] +id: GO:0097546 +name: ciliary base +namespace: cellular_component +def: "Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area." [GOC:cilia, GOC:krc, PMID:22653444] +comment: Due to resolution issues, researchers are often unable to assign protein localization to more specific ciliary compartments such as the basal body, transition fibers or transition zone, and instead refer to 'ciliary base'. The terms GO:0036064 'ciliary basal body', GO:0097539 'ciliary transition fiber' and GO:0035869 'ciliary transition zone' represent strictly defined compartments at the ciliary base and should be used for annotation whenever possible. Also, note that cilia and eukaryotic flagella are deemed to be equivalent. +synonym: "cilial base" EXACT [] +synonym: "cilium base" EXACT [] +synonym: "flagellar base" EXACT [] +synonym: "flagellum base" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0035869 ! ciliary transition zone +relationship: has_part GO:0097539 ! ciliary transition fiber +relationship: part_of GO:0005929 ! cilium +created_by: pr +creation_date: 2013-12-17T14:16:04Z + +[Term] +id: GO:0097547 +name: synaptic vesicle protein transport vesicle +namespace: cellular_component +def: "A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon." [GOC:dr, PMID:21569270] +comment: This term should not be confused with GO:0008021 'synaptic vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles. +synonym: "STV" EXACT [] +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: pr +creation_date: 2013-12-20T09:22:03Z + +[Term] +id: GO:0097548 +name: seed abscission +namespace: biological_process +def: "The controlled shedding of a seed." [GOC:lmo] +is_a: GO:0009838 ! abscission +created_by: pr +creation_date: 2014-01-22T07:57:41Z + +[Term] +id: GO:0097549 +name: chromatin organization involved in negative regulation of transcription +namespace: biological_process +alt_id: GO:1903758 +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization." [GOC:di, PMID:23123093] +subset: gocheck_do_not_manually_annotate +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription by chromatin organization" EXACT [] +synonym: "negative regulation of transcription from Pol II promoter by histone modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter by histone modification" NARROW [] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global by histone modification" NARROW [GOC:TermGenie] +is_a: GO:0034401 ! chromatin organization involved in regulation of transcription +intersection_of: GO:0006325 ! chromatin organization +intersection_of: part_of GO:0045892 ! negative regulation of transcription, DNA-templated +relationship: part_of GO:0045892 ! negative regulation of transcription, DNA-templated +created_by: pr +creation_date: 2014-01-22T08:20:50Z + +[Term] +id: GO:0097550 +name: transcription preinitiation complex +namespace: cellular_component +def: "A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription." [GOC:di, PMID:22751016] +synonym: "DNA-templated transcriptional preinitiation complex" EXACT [] +synonym: "PIC" NARROW [] +synonym: "preinitiation complex" NARROW [] +synonym: "transcription preinitiation complex" EXACT [] +synonym: "transcriptional pre-initiation complex" EXACT [] +synonym: "transcriptional preinitiation complex" EXACT [] +is_a: GO:0032993 ! protein-DNA complex +created_by: pr +creation_date: 2014-01-22T09:33:44Z + +[Term] +id: GO:0097551 +name: mitochondrial double-strand break repair +namespace: biological_process +def: "The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix." [GOC:di, PMID:22214610] +comment: Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable. +synonym: "mtDSB repair" EXACT [] +is_a: GO:0006302 ! double-strand break repair +created_by: pr +creation_date: 2014-01-22T10:06:54Z + +[Term] +id: GO:0097552 +name: mitochondrial double-strand break repair via homologous recombination +namespace: biological_process +def: "The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences." [GOC:di, PMID:22214610] +comment: Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable. +synonym: "mtDSB repair via homologous recombination" EXACT [] +is_a: GO:0000725 ! recombinational repair +is_a: GO:0097551 ! mitochondrial double-strand break repair +created_by: pr +creation_date: 2014-01-22T10:09:10Z + +[Term] +id: GO:0097553 +name: calcium ion transmembrane import into cytosol +namespace: biological_process +def: "A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore." [GOC:vw] +synonym: "calcium transmembrane import into cytosol" BROAD [] +is_a: GO:0060402 ! calcium ion transport into cytosol +is_a: GO:0070588 ! calcium ion transmembrane transport +created_by: pr +creation_date: 2014-01-23T11:05:13Z + +[Term] +id: GO:0097554 +name: left anterior flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "left anterior cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T12:47:41Z + +[Term] +id: GO:0097555 +name: right anterior flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "right anterior cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:18:36Z + +[Term] +id: GO:0097556 +name: left posteriolateral flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "left posteriolateral cilium" EXACT [] +synonym: "left posterolateral cilium" EXACT [] +synonym: "left posterolateral flagellum" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:21:09Z + +[Term] +id: GO:0097557 +name: right posteriolateral flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "right posteriolateral cilium" EXACT [] +synonym: "right posterolateral cilium" EXACT [] +synonym: "right posterolateral flagellum" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:24:55Z + +[Term] +id: GO:0097558 +name: left ventral flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "left ventral cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:26:51Z + +[Term] +id: GO:0097559 +name: right ventral flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "right ventral cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:28:20Z + +[Term] +id: GO:0097560 +name: left caudal flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "left caudal cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:29:44Z + +[Term] +id: GO:0097561 +name: right caudal flagellum +namespace: cellular_component +def: "A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "right caudal cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-02-05T13:31:15Z + +[Term] +id: GO:0097562 +name: left lateral basal body pair +namespace: cellular_component +def: "Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:1902671 ! left anterior basal body +relationship: has_part GO:1902675 ! left ventral basal body +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:09:11Z + +[Term] +id: GO:0097563 +name: left middle basal body pair +namespace: cellular_component +def: "Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:1902673 ! left posteriolateral basal body +relationship: has_part GO:1902677 ! left caudal basal body +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:11:14Z + +[Term] +id: GO:0097564 +name: right lateral basal body pair +namespace: cellular_component +def: "Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:1902672 ! right anterior basal body +relationship: has_part GO:1902676 ! right ventral basal body +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:12:42Z + +[Term] +id: GO:0097565 +name: right middle basal body pair +namespace: cellular_component +def: "Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:1902674 ! right posteriolateral basal body +relationship: has_part GO:1902678 ! right caudal basal body +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:14:05Z + +[Term] +id: GO:0097566 +name: left tetrad +namespace: cellular_component +def: "Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally)." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097562 ! left lateral basal body pair +relationship: has_part GO:0097563 ! left middle basal body pair +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:30:43Z + +[Term] +id: GO:0097567 +name: right tetrad +namespace: cellular_component +def: "Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally)." [GOC:giardia, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097564 ! right lateral basal body pair +relationship: has_part GO:0097565 ! right middle basal body pair +relationship: part_of GO:0042995 ! cell projection +created_by: pr +creation_date: 2014-02-05T16:32:33Z + +[Term] +id: GO:0097568 +name: median body +namespace: cellular_component +def: "A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc." [GOC:giardia, PMID:5961344] +comment: Note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "parabasal body" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005874 ! microtubule +relationship: part_of GO:0005856 ! cytoskeleton +created_by: pr +creation_date: 2014-02-11T13:34:19Z + +[Term] +id: GO:0097569 +name: lateral shield +namespace: cellular_component +def: "Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella." [GOC:giardia, ISBN:9780124260207] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044297 ! cell body +created_by: pr +creation_date: 2014-02-11T13:37:10Z + +[Term] +id: GO:0097570 +name: cyst wall +namespace: cellular_component +def: "The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins." [GOC:giardia, PMID:15134259, PMID:2026212, Wikipedia:Microbial_cyst] +is_a: GO:0005618 ! cell wall +created_by: pr +creation_date: 2014-02-18T10:25:53Z + +[Term] +id: GO:0097571 +name: left nucleus +namespace: cellular_component +def: "One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side." [GOC:giardia, ISBN:0-444-81258-X] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0005634 ! nucleus +created_by: pr +creation_date: 2014-02-18T11:21:31Z + +[Term] +id: GO:0097572 +name: right nucleus +namespace: cellular_component +def: "One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side." [GOC:giardia, ISBN:0-444-81258-X] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +is_a: GO:0005634 ! nucleus +created_by: pr +creation_date: 2014-02-18T11:23:01Z + +[Term] +id: GO:0097573 +name: glutathione oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione." [GOC:jd, PMID:18992757] +comment: Note that this activity is different from GO:0015038 'glutathione disulfide oxidoreductase activity'. See PMID:18992757: "Grxs [glutaredoxins] can also reduce mixed disulfides between proteins or low molecular weight thiols and GSH in reactions that require only their N-terminal active- site cysteine. It is important to note that the reduction of glutathionylated substrates through the monothiol mechanism seems to be the major activity of Grxs; all dithiol Grxs described so far catalyze these reactions, but not all dithiol Grxs catalyze the reduction of protein disulfides by the dithiol mechanism". +is_a: GO:0015035 ! protein disulfide oxidoreductase activity +created_by: pr +creation_date: 2014-02-19T13:41:38Z + +[Term] +id: GO:0097574 +name: lateral part of cell +namespace: cellular_component +def: "The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells." [GOC:pr] +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2014-02-26T13:27:27Z + +[Term] +id: GO:0097575 +name: lateral cell cortex +namespace: cellular_component +def: "The region directly beneath the plasma membrane of the lateral portion of the cell." [GOC:mah, PMID:24146635] +is_a: GO:0099738 ! cell cortex region +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0097574 ! lateral part of cell +relationship: part_of GO:0097574 ! lateral part of cell +created_by: pr +creation_date: 2014-02-26T13:29:22Z + +[Term] +id: GO:0097576 +name: vacuole fusion +namespace: biological_process +def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole] +is_a: GO:0007033 ! vacuole organization +is_a: GO:0048284 ! organelle fusion +created_by: pr +creation_date: 2014-02-28T09:49:31Z + +[Term] +id: GO:0097577 +name: sequestering of iron ion +namespace: biological_process +def: "The process of binding or confining iron ions such that they are separated from other components of a biological system." [GOC:mr, PMID:3099306] +synonym: "iron ion retention" EXACT [] +synonym: "iron ion sequestering" EXACT [] +synonym: "iron ion sequestration" EXACT [] +synonym: "iron ion storage" EXACT [] +synonym: "retention of iron ion" EXACT [] +synonym: "sequestration of iron ion" EXACT [] +synonym: "storage of iron ion" EXACT [] +is_a: GO:0051238 ! sequestering of metal ion +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0006879 ! cellular iron ion homeostasis +created_by: pr +creation_date: 2014-02-28T11:10:53Z + +[Term] +id: GO:0097578 +name: sequestering of copper ion +namespace: biological_process +def: "The process of binding or confining copper ions such that they are separated from other components of a biological system." [GOC:mr, PMID:3099306] +synonym: "copper ion retention" EXACT [] +synonym: "copper ion sequestering" EXACT [] +synonym: "copper ion sequestration" EXACT [] +synonym: "copper ion storage" EXACT [] +synonym: "retention of copper ion" EXACT [] +synonym: "sequestration of copper ion" EXACT [] +synonym: "storage of copper ion" EXACT [] +is_a: GO:0006878 ! cellular copper ion homeostasis +is_a: GO:0051238 ! sequestering of metal ion +is_a: GO:0051651 ! maintenance of location in cell +created_by: pr +creation_date: 2014-02-28T11:15:02Z + +[Term] +id: GO:0097579 +name: extracellular sequestering of copper ion +namespace: biological_process +def: "The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system." [GOC:mr, PMID:3099306] +synonym: "extracellular copper ion retention" EXACT [] +synonym: "extracellular copper ion sequestering" EXACT [] +synonym: "extracellular copper ion sequestration" EXACT [] +synonym: "extracellular copper ion storage" EXACT [] +synonym: "extracellular retention of copper ion" EXACT [] +synonym: "extracellular sequestration of copper ion" EXACT [] +synonym: "extracellular storage of copper ion" EXACT [] +is_a: GO:0097578 ! sequestering of copper ion +intersection_of: GO:0097578 ! sequestering of copper ion +intersection_of: occurs_in GO:0005576 ! extracellular region +relationship: occurs_in GO:0005576 ! extracellular region +relationship: part_of GO:0006878 ! cellular copper ion homeostasis +created_by: pr +creation_date: 2014-02-28T11:18:04Z + +[Term] +id: GO:0097580 +name: intracellular sequestering of copper ion +namespace: biological_process +def: "The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system." [GOC:mr, PMID:3099306] +synonym: "intracellular copper ion retention" EXACT [] +synonym: "intracellular copper ion sequestering" EXACT [] +synonym: "intracellular copper ion sequestration" EXACT [] +synonym: "intracellular copper ion storage" EXACT [] +synonym: "intracellular retention of copper ion" EXACT [] +synonym: "intracellular sequestration of copper ion" EXACT [] +synonym: "intracellular storage of copper ion" EXACT [] +is_a: GO:0097578 ! sequestering of copper ion +intersection_of: GO:0097578 ! sequestering of copper ion +intersection_of: occurs_in GO:0005622 ! intracellular +relationship: occurs_in GO:0005622 ! intracellular +relationship: part_of GO:0006878 ! cellular copper ion homeostasis +created_by: pr +creation_date: 2014-02-28T11:21:39Z + +[Term] +id: GO:0097581 +name: lamellipodium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments." [GOC:als, PMID:16054028] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +created_by: pr +creation_date: 2014-02-28T16:08:56Z + +[Term] +id: GO:0097582 +name: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex +namespace: cellular_component +def: "A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p." [GOC:jd, PMID:12551906] +synonym: "Pmt1p-Pmt2p complex" NARROW [] +is_a: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex +created_by: pr +creation_date: 2014-03-02T18:13:34Z + +[Term] +id: GO:0097583 +name: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex +namespace: cellular_component +def: "A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p." [GOC:jd, PMID:12551906] +synonym: "Pmt1p-Pmt3p complex" NARROW [] +is_a: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex +created_by: pr +creation_date: 2014-03-02T18:16:29Z + +[Term] +id: GO:0097584 +name: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex +namespace: cellular_component +def: "A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p." [GOC:jd, PMID:12551906] +synonym: "Pmt5p-Pmt2p complex" NARROW [] +is_a: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex +created_by: pr +creation_date: 2014-03-02T18:17:22Z + +[Term] +id: GO:0097585 +name: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex +namespace: cellular_component +def: "A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p." [GOC:jd, PMID:12551906] +synonym: "Pmt5p-Pmt3p complex" NARROW [] +is_a: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex +created_by: pr +creation_date: 2014-03-02T18:18:28Z + +[Term] +id: GO:0097586 +name: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex +namespace: cellular_component +def: "A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p." [GOC:bhm, GOC:jd, PMID:12551906] +synonym: "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer" EXACT [] +synonym: "dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex" EXACT [] +synonym: "Pmt4p-Pmt4p complex" NARROW [] +is_a: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex +created_by: pr +creation_date: 2014-03-02T18:19:05Z + +[Term] +id: GO:0097587 +name: MutLgamma complex +namespace: cellular_component +def: "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3." [GOC:jd, PMID:10570173] +is_a: GO:0032300 ! mismatch repair complex +created_by: pr +creation_date: 2014-03-06T11:48:12Z + +[Term] +id: GO:0097588 +name: archaeal or bacterial-type flagellum-dependent cell motility +namespace: biological_process +def: "Cell motility due to movement of bacterial- or archaeal-type flagella." [GOC:cilia, GOC:krc] +comment: Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. This term was added for mapping to the UniProt keyword "flagellar rotation". For manual annotation, please use one of the child terms of GO:0097588 that refer specifically to either archaeal- or bacterial-type flagella. +is_a: GO:0001539 ! cilium or flagellum-dependent cell motility +property_value: RO:0002161 NCBITaxon:2759 +created_by: pr +creation_date: 2014-03-25T16:51:19Z + +[Term] +id: GO:0097589 +name: archaeal-type flagellum +namespace: cellular_component +def: "A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function." [GOC:cilia, GOC:krc, PMID:21265748, PMID:23146836, PMID:23204365, PMID:24330313, Wikipedia:Flagellum#Archaeal] +synonym: "archaeal flagellum" RELATED [] +synonym: "archaella" RELATED [] +synonym: "archaellum" EXACT [] +is_a: GO:0042995 ! cell projection +is_a: GO:0043228 ! non-membrane-bounded organelle +created_by: pr +creation_date: 2014-03-25T20:36:24Z + +[Term] +id: GO:0097590 +name: archaeal-type flagellum-dependent cell motility +namespace: biological_process +def: "Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel." [GOC:cilia, GOC:krc, Wikipedia:Flagellum#Archaeal] +synonym: "archaeal-type flagellar cell motility" RELATED [] +is_a: GO:0097588 ! archaeal or bacterial-type flagellum-dependent cell motility +created_by: pr +creation_date: 2014-03-25T20:40:50Z + +[Term] +id: GO:0097591 +name: ventral disc lateral crest +namespace: cellular_component +def: "Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet." [GOC:giardia] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "lateral crest" BROAD [] +synonym: "ventral disk lateral crest" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T10:47:48Z + +[Term] +id: GO:0097592 +name: ventral disc overlap zone +namespace: cellular_component +def: "A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself)." [GOC:giardia] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "overlap zone" BROAD [] +synonym: "ventral disk overlap zone" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097593 ! ventral disc microtubule array +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T11:12:50Z + +[Term] +id: GO:0097593 +name: ventral disc microtubule array +namespace: cellular_component +def: "A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane." [GOC:giardia] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "spiral microtubule array" BROAD [] +synonym: "ventral disc spiral microtubule array" EXACT [] +synonym: "ventral disk microtubule array" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005874 ! microtubule +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T11:17:17Z + +[Term] +id: GO:0097594 +name: ventral disc dorsal microribbon +namespace: cellular_component +def: "Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons." [GOC:giardia, PMID:11432808] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "dorsal microribbon" BROAD [] +synonym: "dorsal ribbon" BROAD [] +synonym: "microribbon" BROAD [] +synonym: "ventral disk dorsal microribbon" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T11:20:06Z + +[Term] +id: GO:0097595 +name: ventral disc crossbridge +namespace: cellular_component +def: "Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet." [GOC:giardia] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "crossbridge" BROAD [] +synonym: "ventral disk crossbridge" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T11:23:33Z + +[Term] +id: GO:0097596 +name: ventral disc supernumerary microtubule array +namespace: cellular_component +def: "A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage)." [GOC:giardia, ISBN:9780124260207] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "supernumerary microtubule array" BROAD [] +synonym: "ventral disk supernumerary microtubule array" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005874 ! microtubule +relationship: part_of GO:0097597 ! ventral disc +created_by: pr +creation_date: 2014-04-03T11:25:07Z + +[Term] +id: GO:0097597 +name: ventral disc +namespace: cellular_component +def: "Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence." [GOC:giardia, ISBN:9780124260207, PMID:11432808, PMID:4777416, PMID:5961344] +comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "adhesive disc" RELATED [] +synonym: "ventral adhesive disc" EXACT [] +synonym: "ventral disk" RELATED [] +is_a: GO:0043226 ! organelle +relationship: has_part GO:0097591 ! ventral disc lateral crest +relationship: has_part GO:0097592 ! ventral disc overlap zone +relationship: has_part GO:0097594 ! ventral disc dorsal microribbon +relationship: has_part GO:0097595 ! ventral disc crossbridge +created_by: pr +creation_date: 2014-04-03T11:29:58Z + +[Term] +id: GO:0097598 +name: sperm cytoplasmic droplet +namespace: cellular_component +def: "A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted." [GOC:krc, GOC:vesicles, PMID:12672117, PMID:21076437, PMID:23159014] +synonym: "sperm residual cytoplasm" EXACT [] +is_a: GO:0097708 ! intracellular vesicle +created_by: pr +creation_date: 2014-04-10T14:03:30Z + +[Term] +id: GO:0097599 +name: xylanase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues." [GOC:jh2, ISBN:81-7736-269-0] +synonym: "xylosidase activity" RELATED [] +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds +created_by: pr +creation_date: 2014-05-06T13:46:48Z + +[Term] +id: GO:0097600 +name: exoxylanase activity +namespace: molecular_function +def: "A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains." [GOC:jh2, ISBN:81-7736-269-0, PMID:16535010] +is_a: GO:0097599 ! xylanase activity +created_by: pr +creation_date: 2014-05-06T13:48:27Z + +[Term] +id: GO:0097601 +name: retina blood vessel maintenance +namespace: biological_process +def: "A retina homeostatic process preventing the degeneration of a retina blood vessel." [GOC:jh2, PMID:23093773] +synonym: "maintenance of choriocapillaris" NARROW [] +synonym: "maintenance of retina blood vessel" EXACT [] +synonym: "maintenance of retinal blood vessel" EXACT [] +is_a: GO:0001895 ! retina homeostasis +created_by: pr +creation_date: 2014-05-11T18:42:24Z + +[Term] +id: GO:0097602 +name: cullin family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3)." [GOC:ha, InterPro:IPR016158, PMID:18698375] +synonym: "cullin binding" NARROW [] +is_a: GO:0005515 ! protein binding +created_by: pr +creation_date: 2014-05-11T20:41:10Z + +[Term] +id: GO:0097603 +name: temperature-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism)." [GOC:ha, GOC:pr, PMID:23027824] +synonym: "heat-activated ion channel activity" NARROW [] +synonym: "temperature gated ion channel activity" EXACT [] +synonym: "temperature-activated ion channel activity" EXACT [] +synonym: "temperature-dependent ion channel activity" EXACT [] +is_a: GO:0005216 ! ion channel activity +is_a: GO:0022836 ! gated channel activity +created_by: pr +creation_date: 2014-05-12T13:10:42Z + +[Term] +id: GO:0097604 +name: temperature-gated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism)." [GOC:ha, GOC:pr, PMID:23027824] +synonym: "heat-activated cation channel activity" NARROW [] +synonym: "temperature gated cation channel activity" EXACT [] +synonym: "temperature-activated cation channel activity" EXACT [] +synonym: "temperature-dependent cation channel activity" EXACT [] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0097603 ! temperature-gated ion channel activity +created_by: pr +creation_date: 2014-05-12T13:13:46Z + +[Term] +id: GO:0097605 +name: obsolete regulation of nuclear envelope permeability +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope." [GOC:pr] +comment: The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it. +synonym: "regulation of nuclear membrane permeability" RELATED [] +is_obsolete: true +created_by: pr +creation_date: 2014-05-14T15:41:44Z + +[Term] +id: GO:0097606 +name: obsolete positive regulation of nuclear envelope permeability +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope." [GOC:pr] +comment: The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it. +synonym: "positive regulation of nuclear membrane permeability" RELATED [] +is_obsolete: true +created_by: pr +creation_date: 2014-05-14T15:43:06Z + +[Term] +id: GO:0097607 +name: obsolete negative regulation of nuclear envelope permeability +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope." [GOC:pr] +comment: The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it. +synonym: "negative regulation of nuclear membrane permeability" RELATED [] +is_obsolete: true +created_by: pr +creation_date: 2014-05-14T15:43:47Z + +[Term] +id: GO:0097608 +name: transverse flagellum +namespace: cellular_component +def: "A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate. +synonym: "transverse cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-06-09T11:14:37Z + +[Term] +id: GO:0097609 +name: longitudinal flagellum +namespace: cellular_component +def: "A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate. +synonym: "longitudinal cilium" EXACT [] +is_a: GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2014-06-09T11:21:10Z + +[Term] +id: GO:0097610 +name: cell surface furrow +namespace: cellular_component +def: "A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates." [GOC:pr] +synonym: "cell surface groove" RELATED [] +synonym: "furrow" BROAD [] +synonym: "groove" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009986 ! cell surface +created_by: pr +creation_date: 2014-06-09T11:22:38Z + +[Term] +id: GO:0097611 +name: dinoflagellate cingulum +namespace: cellular_component +def: "A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "cingulum" BROAD [] +synonym: "girdle" RELATED [] +synonym: "transverse groove" RELATED [] +is_a: GO:0097610 ! cell surface furrow +created_by: pr +creation_date: 2014-06-09T11:28:22Z + +[Term] +id: GO:0097612 +name: dinoflagellate sulcus +namespace: cellular_component +def: "A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side). +synonym: "longitudinal furrow" RELATED [] +synonym: "longitudinal groove" RELATED [] +synonym: "sulcus" BROAD [] +is_a: GO:0097610 ! cell surface furrow +created_by: pr +creation_date: 2014-06-09T11:31:05Z + +[Term] +id: GO:0097613 +name: dinoflagellate epicone +namespace: cellular_component +def: "The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "epicone" BROAD [] +synonym: "episome" RELATED [] +synonym: "epitheca" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2014-06-09T11:32:48Z + +[Term] +id: GO:0097614 +name: dinoflagellate hypocone +namespace: cellular_component +def: "The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "hypocone" BROAD [] +synonym: "hyposome" RELATED [] +synonym: "hypotheca" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2014-06-09T11:35:07Z + +[Term] +id: GO:0097615 +name: modulation by host of symbiont type IV pilus-dependent motility +namespace: biological_process +def: "The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:als, PMID:12037568] +synonym: "modulation by host of bacterial type IV pilus-dependent motility" EXACT [] +is_a: GO:0051851 ! modulation by host of symbiont process +created_by: pr +creation_date: 2014-06-10T13:17:13Z + +[Term] +id: GO:0097616 +name: positive regulation by host of symbiont type IV pilus-dependent motility +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:als, PMID:12037568] +synonym: "positive regulation by host of bacterial type IV pilus-dependent motility" EXACT [] +is_a: GO:0097615 ! modulation by host of symbiont type IV pilus-dependent motility +created_by: pr +creation_date: 2014-06-10T13:19:51Z + +[Term] +id: GO:0097617 +name: annealing activity +namespace: molecular_function +def: "A nucleic acid binding activity that brings together complementary sequences of nucleic acids so that they pair by hydrogen bonds to form a double-stranded polynucleotide." [GOC:mba, Wikipedia:Nucleic_acid_thermodynamics#Annealing] +comment: The term 'annealing' is often used to describe the binding of a DNA probe, or the binding of a primer to a DNA strand during a polymerase chain reaction. The term is also often used to describe the reformation (renaturation) of complementary strands that were separated by heat (thermally denatured). For example, proteins such as RAD52 can help DNA anneal. If at all possible, please annotate to the more specific terms GO:0036310 'annealing helicase activity', GO:0097098 'DNA/RNA hybrid annealing activity' or GO:0033592 'RNA strand annealing activity'. +synonym: "renaturation" RELATED [] +xref: Reactome:R-HSA-5686642 "RAD52 promotes single strand annealing at resected DNA DSBs" +is_a: GO:0003676 ! nucleic acid binding +created_by: pr +creation_date: 2014-06-13T10:18:43Z + +[Term] +id: GO:0097618 +name: dinoflagellate sulcal notch +namespace: cellular_component +def: "A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side). The term 'sulcal notch' appears mostly in older literature; more recently, indication of a bilobed hypocone is used to express the same. +synonym: "dinoflagellate sulcus notch" EXACT [] +synonym: "sulcal notch" RELATED [] +is_a: GO:0097612 ! dinoflagellate sulcus +created_by: pr +creation_date: 2014-06-27T16:28:49Z + +[Term] +id: GO:0097619 +name: PTEX complex +namespace: cellular_component +def: "A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components." [GOC:pr, PMID:19536257, PMID:25043010, PMID:25043043] +synonym: "Plasmodium translocon of exported proteins" RELATED [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0020005 ! symbiont-containing vacuole membrane +created_by: pr +creation_date: 2014-07-29T16:05:32Z + +[Term] +id: GO:0097620 +name: (R)-mandelate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor." [GOC:pr, PMID:1731758, RHEA:43112] +comment: In the yeast Rhodotorula graminis, (R)-mandelate dehydrogenase is the first enzyme of the mandelate pathway, and catalyzes the NAD-dependent oxidation of (R)-mandelate to phenylglyoxylate. +synonym: "D-mandelate dehydrogenase activity" EXACT [] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors +created_by: pr +creation_date: 2014-07-30T09:53:23Z + +[Term] +id: GO:0097621 +name: monoamine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2." [EC:1.4.3.4, GOC:pr, RHEA:26414] +comment: Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC:1.4.3.21, primary-amine oxidase as it can oxidize secondary and tertiary amines but not methylamine. +synonym: "amine:oxygen oxidoreductase (deaminating) activity" EXACT [] +is_a: GO:0016641 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor +created_by: pr +creation_date: 2014-07-30T10:23:57Z + +[Term] +id: GO:0097622 +name: cytoplasmic translational elongation through polyproline stretches +namespace: biological_process +def: "The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm." [GOC:mcc, PMID:24923804] +is_a: GO:0002182 ! cytoplasmic translational elongation +created_by: pr +creation_date: 2014-08-06T16:29:10Z + +[Term] +id: GO:0097623 +name: potassium ion export across plasma membrane +namespace: biological_process +alt_id: GO:0071435 +alt_id: GO:0098668 +def: "The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:vw, PMID:11932440] +synonym: "potassium export" BROAD [GOC:mah] +synonym: "potassium export across plasma membrane" EXACT [] +synonym: "potassium ion export" BROAD [] +synonym: "potassium ion export from cell" EXACT [] +is_a: GO:0071805 ! potassium ion transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14265 xsd:anyURI +created_by: pr +creation_date: 2009-12-16T11:10:45Z + +[Term] +id: GO:0097624 +name: UDP-galactose transmembrane import into Golgi lumen +namespace: biological_process +def: "The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane." [GOC:vw, PMID:11378902] +synonym: "UDP-galactose import into Golgi lumen" BROAD [] +is_a: GO:0072334 ! UDP-galactose transmembrane transport +created_by: pr +creation_date: 2014-08-18T14:59:23Z + +[Term] +id: GO:0097625 +name: low-affinity basic amino acid transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:pr] +synonym: "low affinity basic amino acid transmembrane transporter activity" EXACT [] +is_a: GO:0015174 ! basic amino acid transmembrane transporter activity +created_by: pr +creation_date: 2014-08-20T14:23:18Z + +[Term] +id: GO:0097626 +name: low-affinity L-arginine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:krc, PMID:8195186] +synonym: "low affinity L-arginine transmembrane transporter activity" EXACT [] +is_a: GO:0061459 ! L-arginine transmembrane transporter activity +is_a: GO:0097625 ! low-affinity basic amino acid transmembrane transporter activity +created_by: pr +creation_date: 2014-08-20T14:24:22Z + +[Term] +id: GO:0097627 +name: high-affinity L-ornithine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:krc, PMID:8195186] +synonym: "high affinity L-ornithine transmembrane transporter activity" EXACT [] +is_a: GO:0000064 ! L-ornithine transmembrane transporter activity +created_by: pr +creation_date: 2014-08-20T14:26:33Z + +[Term] +id: GO:0097628 +name: distal tip cell migration +namespace: biological_process +def: "The orderly movement of a distal tip cell." [CL:0000661, GOC:mm2, PMID:24968003] +is_a: GO:0016477 ! cell migration +created_by: pr +creation_date: 2014-08-20T16:06:53Z + +[Term] +id: GO:0097629 +name: extrinsic component of omegasome membrane +namespace: cellular_component +def: "The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:mf, PMID:18725538, PMID:24591649] +synonym: "extrinsic to omegasome membrane" EXACT [] +synonym: "omegasome peripheral membrane" RELATED [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:1903349 ! omegasome membrane +relationship: part_of GO:1903349 ! omegasome membrane + +[Term] +id: GO:0097630 +name: intrinsic component of omegasome membrane +namespace: cellular_component +def: "The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:mf, PMID:18725538, PMID:24591649] +synonym: "intrinsic to omegasome membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:1903349 ! omegasome membrane +relationship: part_of GO:1903349 ! omegasome membrane + +[Term] +id: GO:0097631 +name: integral component of omegasome membrane +namespace: cellular_component +def: "The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:mf, PMID:18725538, PMID:24591649] +synonym: "integral to omegasome membrane" NARROW [] +synonym: "omegasome integral membrane protein" RELATED [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0097630 ! intrinsic component of omegasome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:1903349 ! omegasome membrane + +[Term] +id: GO:0097632 +name: extrinsic component of phagophore assembly site membrane +namespace: cellular_component +def: "The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:mf] +synonym: "extrinsic component of pre-autophagosomal structure membrane" NARROW [] +synonym: "extrinsic to phagophore assembly site membrane" EXACT [] +synonym: "phagophore assembly site peripheral membrane" RELATED [] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0034045 ! phagophore assembly site membrane +relationship: part_of GO:0034045 ! phagophore assembly site membrane + +[Term] +id: GO:0097633 +name: intrinsic component of phagophore assembly site membrane +namespace: cellular_component +def: "The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:mf] +synonym: "intrinsic to phagophore assembly site membrane" NARROW [] +is_a: GO:0031224 ! intrinsic component of membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0034045 ! phagophore assembly site membrane +relationship: part_of GO:0034045 ! phagophore assembly site membrane + +[Term] +id: GO:0097634 +name: integral component of phagophore assembly site membrane +namespace: cellular_component +def: "The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:mf] +synonym: "integral to phagophore assembly site membrane" NARROW [] +synonym: "phagophore assembly site integral membrane protein" RELATED [] +is_a: GO:0016021 ! integral component of membrane +is_a: GO:0097633 ! intrinsic component of phagophore assembly site membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0034045 ! phagophore assembly site membrane + +[Term] +id: GO:0097635 +name: extrinsic component of autophagosome membrane +namespace: cellular_component +def: "The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +synonym: "autophagic vacuole peripheral membrane" RELATED [] +synonym: "extrinsic component of autophagic vacuole membrane" EXACT [GOC:autophagy] +synonym: "extrinsic to autophagic vacuole membrane" EXACT [] +is_a: GO:0000306 ! extrinsic component of vacuolar membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0000421 ! autophagosome membrane +relationship: part_of GO:0000421 ! autophagosome membrane + +[Term] +id: GO:0097636 +name: intrinsic component of autophagosome membrane +namespace: cellular_component +def: "The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:autophagy, GOC:mf] +synonym: "intrinsic component of autophagic vacuole membrane" EXACT [GOC:autophagy] +synonym: "intrinsic to autophagic vacuole membrane" NARROW [] +is_a: GO:0031310 ! intrinsic component of vacuolar membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0000421 ! autophagosome membrane +relationship: part_of GO:0000421 ! autophagosome membrane + +[Term] +id: GO:0097637 +name: integral component of autophagosome membrane +namespace: cellular_component +def: "The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:autophagy, GOC:mf] +synonym: "autophagic vacuole integral membrane protein" RELATED [] +synonym: "integral component of autophagic vacuole membrane" EXACT [GOC:autophagy] +synonym: "integral to autophagic vacuole membrane" NARROW [] +is_a: GO:0031166 ! integral component of vacuolar membrane +is_a: GO:0097636 ! intrinsic component of autophagosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0000421 ! autophagosome membrane + +[Term] +id: GO:0097638 +name: L-arginine import across plasma membrane +namespace: biological_process +alt_id: GO:0090467 +alt_id: GO:1902765 +def: "The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:krc, PMID:8195186] +synonym: "arginine import" BROAD [] +synonym: "L-arginine import into cell" EXACT [] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1903400 ! L-arginine transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:28:58Z + +[Term] +id: GO:0097639 +name: L-lysine import across plasma membrane +namespace: biological_process +alt_id: GO:1903410 +def: "The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:krc, PMID:8195186] +synonym: "L-lysine import into cell" EXACT [] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1903401 ! L-lysine transmembrane transport +created_by: pr +creation_date: 2014-09-03T09:32:57Z + +[Term] +id: GO:0097640 +name: L-ornithine import across plasma membrane +namespace: biological_process +alt_id: GO:1903411 +def: "The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:krc, PMID:8195186] +synonym: "L-ornithine import into cell" EXACT [] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1903352 ! L-ornithine transmembrane transport +created_by: pr +creation_date: 2014-09-03T09:48:14Z + +[Term] +id: GO:0097641 +name: alpha-ketoglutarate-dependent xanthine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate." [GOC:vw, PMID:15948966, PMID:17429948, RHEA:43120] +synonym: "2-oxoglutarate-dependent xanthine dioxygenase activity" EXACT [] +synonym: "alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity" RELATED [] +synonym: "alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity" RELATED [] +is_a: GO:0051213 ! dioxygenase activity +created_by: pr +creation_date: 2014-09-03T14:55:42Z + +[Term] +id: GO:0097642 +name: calcitonin family receptor activity +namespace: molecular_function +def: "Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity." [GOC:bhm, InterPro:IPR003287, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:0008528 ! G protein-coupled peptide receptor activity +created_by: pr +creation_date: 2014-09-08T15:32:19Z + +[Term] +id: GO:0097643 +name: amylin receptor activity +namespace: molecular_function +def: "Combining with amylin to initiate a change in cell activity." [GOC:bhm, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:0097642 ! calcitonin family receptor activity +created_by: pr +creation_date: 2014-09-08T15:34:16Z + +[Term] +id: GO:0097644 +name: calcitonin family binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs))." [GOC:bhm, InterPro:IPR021116, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:0017046 ! peptide hormone binding +created_by: pr +creation_date: 2014-09-08T20:50:52Z + +[Term] +id: GO:0097645 +name: amylin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with amylin." [GOC:bhm, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:0097644 ! calcitonin family binding +created_by: pr +creation_date: 2014-09-08T20:53:03Z + +[Term] +id: GO:0097646 +name: calcitonin family receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far." [GOC:bhm, PMID:10871296, PMID:12037140, PMID:18687416] +synonym: "calcitonin family receptor signalling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +created_by: pr +creation_date: 2014-09-09T17:48:05Z + +[Term] +id: GO:0097647 +name: amylin receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell." [GOC:bhm, PMID:10871296, PMID:12037140, PMID:18687416] +synonym: "amilyn receptor signalling pathway" EXACT [] +is_a: GO:0097646 ! calcitonin family receptor signaling pathway +created_by: pr +creation_date: 2014-09-09T17:49:52Z + +[Term] +id: GO:0097648 +name: G protein-coupled receptor complex +namespace: cellular_component +def: "A protein complex that contains G protein-coupled receptors." [GOC:bhm] +synonym: "G-protein coupled receptor complex" EXACT [] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: pr +creation_date: 2014-09-10T09:14:30Z + +[Term] +id: GO:0097649 +name: A axonemal microtubule +namespace: cellular_component +def: "A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule." [GOC:cilia, ISBN:0716731363] +synonym: "A tubule" BROAD [] +is_a: GO:0005879 ! axonemal microtubule +relationship: part_of GO:0097545 ! axonemal outer doublet +created_by: pr +creation_date: 2014-09-10T20:41:28Z + +[Term] +id: GO:0097650 +name: B axonemal microtubule +namespace: cellular_component +def: "An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet." [GOC:cilia, ISBN:0716731363] +synonym: "B tubule" BROAD [] +is_a: GO:0005879 ! axonemal microtubule +relationship: part_of GO:0097545 ! axonemal outer doublet +created_by: pr +creation_date: 2014-09-10T20:43:18Z + +[Term] +id: GO:0097651 +name: phosphatidylinositol 3-kinase complex, class I +namespace: cellular_component +def: "A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast." [GOC:ha, PMID:24587488] +synonym: "class I phosphatidylinositol 3-kinase complex" EXACT [] +synonym: "class I PI3K complex" EXACT [] +is_a: GO:0005942 ! phosphatidylinositol 3-kinase complex +property_value: RO:0002161 NCBITaxon:4932 +created_by: pr +creation_date: 2014-09-16T11:19:58Z + +[Term] +id: GO:0097652 +name: phosphatidylinositol 3-kinase complex, class II +namespace: cellular_component +def: "A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast." [GOC:ha, PMID:24587488] +synonym: "class II phosphatidylinositol 3-kinase complex" EXACT [] +synonym: "class II PI3K complex" EXACT [] +is_a: GO:0005942 ! phosphatidylinositol 3-kinase complex +property_value: RO:0002161 NCBITaxon:4932 +created_by: pr +creation_date: 2014-09-16T13:14:17Z + +[Term] +id: GO:0097653 +name: unencapsulated part of cell +namespace: cellular_component +def: "The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures." [GOC:curators] +synonym: "non-encapsulated part of cell" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005622 ! intracellular +relationship: has_part GO:0005886 ! plasma membrane +created_by: pr +creation_date: 2014-09-23T12:57:14Z + +[Term] +id: GO:0097654 +name: platelet SNARE complex +namespace: cellular_component +def: "A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4." [GOC:bhm, PMID:12130530, PMID:19450911] +is_a: GO:0031201 ! SNARE complex +created_by: pr +creation_date: 2014-09-24T13:50:49Z + +[Term] +id: GO:0097655 +name: serpin family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors." [GOC:mr, InterPro:IPR000215, PMID:16737556] +synonym: "SERPIN family protein binding" EXACT [] +is_a: GO:0005515 ! protein binding +created_by: pr +creation_date: 2014-09-24T16:19:31Z + +[Term] +id: GO:0097656 +name: cell-cell self recognition +namespace: biological_process +def: "A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development." [GOC:pf, PMID:21700835, PMID:23910661] +comment: Examples are the membrane proteins TgrB1 and TgrC1 in the social amoeba Dictyostelium discoideum. +synonym: "kin discrimination" RELATED [] +synonym: "kin recognition" BROAD [] +synonym: "self recognition" BROAD [] +is_a: GO:0009988 ! cell-cell recognition +created_by: pr +creation_date: 2014-09-24T20:58:35Z + +[Term] +id: GO:0097657 +name: 3',5'-nucleotide bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',5'-nucleotide bisphosphate + H20 = 5'-nucleotide monophosphate + phosphate." [GOC:jh2, PMID:24401123, RHEA:43532] +is_a: GO:0016791 ! phosphatase activity +created_by: pr +creation_date: 2014-09-25T11:21:39Z + +[Term] +id: GO:0097658 +name: Asi complex +namespace: cellular_component +def: "A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p." [GOC:mcc, PMID:25236469] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005637 ! nuclear inner membrane +created_by: pr +creation_date: 2014-09-29T15:08:29Z + +[Term] +id: GO:0097659 +name: nucleic acid-templated transcription +namespace: biological_process +def: "The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA)." [GOC:pr, GOC:txnOH, GOC:vw] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +subset: goslim_mouse +is_a: GO:0032774 ! RNA biosynthetic process +created_by: pr +creation_date: 2014-10-01T13:49:27Z + +[Term] +id: GO:0097660 +name: SCF-Cdc4 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae." [GOC:jd, GOC:vw, PMID:9346238] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:23:13Z + +[Term] +id: GO:0097661 +name: SCF-Ctf13 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:25:56Z + +[Term] +id: GO:0097662 +name: SCF-Das1 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:26:27Z + +[Term] +id: GO:0097663 +name: SCF-Dia2/Pof3 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe)." [GOC:jd, GOC:vw, PMID:14747994, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:26:44Z + +[Term] +id: GO:0097664 +name: SCF-Grr1/Pof2 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe)." [GOC:jd, GOC:vw, PMID:10213692, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:27:10Z + +[Term] +id: GO:0097665 +name: SCF-Mdm30 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:27:30Z + +[Term] +id: GO:0097666 +name: SCF-Met30/Pof1 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe)." [GOC:jd, GOC:vw, PMID:15147268, PMID:9499404] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:27:49Z + +[Term] +id: GO:0097667 +name: SCF-Rcy1/Pof6 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe)." [GOC:jd, GOC:vw, PMID:14747994, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:28:09Z + +[Term] +id: GO:0097668 +name: SCF-Saf1/Pof9 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe)." [GOC:jd, GOC:vw, PMID:11283612, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:28:30Z + +[Term] +id: GO:0097669 +name: SCF-Skp2 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:28:52Z + +[Term] +id: GO:0097670 +name: SCF-Ufo1/Pof10 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe)." [GOC:jd, GOC:vw, PMID:14747994, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:29:13Z + +[Term] +id: GO:0097671 +name: SCF-YDR131C ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:29:35Z + +[Term] +id: GO:0097672 +name: SCF-Pof5 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae)." [GOC:jd, GOC:vw, PMID:14747994, PMID:15147268] +synonym: "SCF-YDR306C ubiquitin ligase complex" RELATED [] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:30:10Z + +[Term] +id: GO:0097673 +name: SCF-Ucc1 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae." [GOC:jd, GOC:vw, PMID:14747994, PMID:25982115] +synonym: "SCF-YLR224W ubiquitin ligase complex" EXACT [PMID:14747994] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:30:31Z + +[Term] +id: GO:0097674 +name: SCF-YLR352W ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae." [GOC:jd, GOC:vw, PMID:19882662] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:30:54Z + +[Term] +id: GO:0097675 +name: SCF-Hrt3/Pof7 ubiquitin ligase complex +namespace: cellular_component +def: "An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe)." [GOC:jd, GOC:vw, PMID:14747994, PMID:15147268] +is_a: GO:0019005 ! SCF ubiquitin ligase complex +created_by: pr +creation_date: 2014-10-06T10:31:14Z + +[Term] +id: GO:0097676 +name: histone H3-K36 dimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone." [GOC:lb, PMID:21187428] +is_a: GO:0010452 ! histone H3-K36 methylation +is_a: GO:0018027 ! peptidyl-lysine dimethylation +created_by: pr +creation_date: 2014-11-04T10:38:05Z + +[Term] +id: GO:0097677 +name: STAT family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses." [GOC:mr, InterPro:IPR001217, PMID:21447371, PMID:24470978] +synonym: "signal transducers and activators of transcription family protein binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2014-11-04T11:31:03Z + +[Term] +id: GO:0097678 +name: SOCS family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions." [GOC:mr, InterPro:IPR028413, PMID:23885323, PMID:24705897] +synonym: "suppressor of cytokine signaling family protein binding" EXACT [] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2014-11-04T11:32:49Z + +[Term] +id: GO:0097680 +name: double-strand break repair via classical nonhomologous end joining +namespace: biological_process +def: "An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining)." [GOC:rph, PMID:18584027] +synonym: "C-NHEJ" RELATED [] +synonym: "canonical nonhomologous end joining" EXACT [] +is_a: GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: pr +creation_date: 2014-12-17T15:15:18Z + +[Term] +id: GO:0097681 +name: double-strand break repair via alternative nonhomologous end joining +namespace: biological_process +def: "An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment." [GOC:rph, PMID:18584027, PMID:21655080, Wikipedia:Microhomology-mediated_end_joining] +synonym: "A-NHEJ" RELATED [] +synonym: "alt-NHEJ" RELATED [] +synonym: "double-strand break repair via microhomology-mediated end joining" EXACT [] +synonym: "MMEJ" RELATED [] +is_a: GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: pr +creation_date: 2014-12-17T15:17:45Z + +[Term] +id: GO:0097682 +name: intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts." [GOC:ha, PMID:24375408] +is_a: GO:0005217 ! intracellular ligand-gated ion channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity +created_by: pr +creation_date: 2014-12-17T16:50:30Z + +[Term] +id: GO:0097683 +name: dinoflagellate apex +namespace: cellular_component +def: "The anterior most point of a dinoflagellate epicone." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "apex" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097613 ! dinoflagellate epicone +created_by: pr +creation_date: 2014-12-18T09:29:51Z + +[Term] +id: GO:0097684 +name: dinoflagellate antapex +namespace: cellular_component +def: "The anterior most point of a dinoflagellate hypocone." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "antapex" BROAD [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097614 ! dinoflagellate hypocone +created_by: pr +creation_date: 2014-12-18T09:32:10Z + +[Term] +id: GO:0097685 +name: dinoflagellate apical groove +namespace: cellular_component +def: "A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex." [GOC:at, http://tolweb.org/Dinoflagellates/2445, http://www.sms.si.edu/irlspec/Phyl_Dinofl_Glossary.htm, ISBN:0632009152, Wikipedia:Dinoflagellate#Morphology] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +synonym: "apical groove" BROAD [] +is_a: GO:0097610 ! cell surface furrow +relationship: part_of GO:0097613 ! dinoflagellate epicone +created_by: pr +creation_date: 2014-12-18T09:34:52Z + +[Term] +id: GO:0097686 +name: dinoflagellate apical horn +namespace: cellular_component +def: "A horn-shaped dinoflagellate apex found in thecate species." [GOC:at, http://species-identification.org] +is_a: GO:0097683 ! dinoflagellate apex +created_by: pr +creation_date: 2014-12-18T09:38:15Z + +[Term] +id: GO:0097687 +name: dinoflagellate antapical horn +namespace: cellular_component +def: "A horn-shaped dinoflagellate antapex found in thecate species." [GOC:at, http://species-identification.org] +is_a: GO:0097684 ! dinoflagellate antapex +created_by: pr +creation_date: 2014-12-18T09:39:57Z + +[Term] +id: GO:0097688 +name: glutamate receptor clustering +namespace: biological_process +def: "The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane." [GOC:krc, PMID:19723286] +synonym: "glutamatergic receptor clustering" EXACT [] +is_a: GO:0072578 ! neurotransmitter-gated ion channel clustering +created_by: pr +creation_date: 2015-02-11T11:49:13Z + +[Term] +id: GO:0097690 +name: iron ion transmembrane transporter inhibitor activity +namespace: molecular_function +def: "An activity that stops, prevents, or reduces the activity of an iron ion transmembrane transporter." [GOC:BHF, GOC:kom, PMID:15514116] +comment: An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116). +synonym: "iron channel inhibitor activity" EXACT [] +is_a: GO:0098772 ! molecular function regulator +intersection_of: GO:0098772 ! molecular function regulator +intersection_of: negatively_regulates GO:0005381 ! iron ion transmembrane transporter activity +relationship: negatively_regulates GO:0005381 ! iron ion transmembrane transporter activity + +[Term] +id: GO:0097691 +name: bacterial extracellular vesicle +namespace: cellular_component +def: "Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells." [GOC:aa, PMID:25704309] +is_a: GO:1903561 ! extracellular vesicle +created_by: pr +creation_date: 2015-09-24T11:31:44Z + +[Term] +id: GO:0097692 +name: histone H3-K4 monomethylation +namespace: biological_process +def: "The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone." [GOC:jh2, PMID:26320581] +is_a: GO:0051568 ! histone H3-K4 methylation +created_by: pr +creation_date: 2015-11-05T11:23:15Z + +[Term] +id: GO:0097693 +name: ocelloid +namespace: cellular_component +def: "Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids." [GOC:ar, PMID:26131935] +is_a: GO:0043229 ! intracellular organelle +relationship: has_part GO:0005739 ! mitochondrion +relationship: has_part GO:0009536 ! plastid +created_by: pr +creation_date: 2015-11-13T14:27:01Z + +[Term] +id: GO:0097694 +name: establishment of RNA localization to telomere +namespace: biological_process +def: "The directed movement of RNA to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:BHF_telomere, GOC:rph, PMID:26586433] +synonym: "establishment of RNA localisation to telomere" EXACT [] +is_a: GO:0051236 ! establishment of RNA localization +created_by: pr +creation_date: 2015-12-22T09:33:43Z + +[Term] +id: GO:0097695 +name: establishment of protein-containing complex localization to telomere +namespace: biological_process +def: "The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome." [GOC:BHF, GOC:BHF_telomere, GOC:rph, PMID:26586433] +synonym: "establishment of macromolecular complex localisation to telomere" EXACT [] +synonym: "establishment of macromolecular complex localization to telomere" RELATED [] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0070200 ! establishment of protein localization to telomere +relationship: part_of GO:0070727 ! cellular macromolecule localization +created_by: pr +creation_date: 2015-12-22T09:38:13Z + +[Term] +id: GO:0097696 +name: receptor signaling pathway via STAT +namespace: biological_process +def: "An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins." [GOC:rjd, PMID:21534947, PMID:24587195] +comment: In most species, STAT proteins are activated by members of the JAK (Janus Activated Kinase) family of tyrosine kinases; the term GO:0007259 'JAK-STAT cascade' describes this specificity. In other cases, such as D. discoideum, no JAK orthologs are known, and STAT proteins are activated by tyrosine kinase-like proteins. +synonym: "kinase activated-STAT cascade" EXACT [] +synonym: "kinase-STAT cascade" EXACT [] +synonym: "STAT signalling pathway" EXACT [] +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: pr +creation_date: 2015-12-22T10:40:14Z + +[Term] +id: GO:0097697 +name: tRNA 5-carboxymethoxyuridine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule." [GOC:imk, PMID:26681692] +is_a: GO:0016300 ! tRNA (uracil) methyltransferase activity +created_by: pr +creation_date: 2016-01-07T10:36:46Z + +[Term] +id: GO:0097698 +name: telomere maintenance via base-excision repair +namespace: biological_process +def: "A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature." [GOC:BHF, GOC:BHF_telomere, GOC:jbu, PMID:24703901] +is_a: GO:0006284 ! base-excision repair +is_a: GO:0043247 ! telomere maintenance in response to DNA damage +created_by: pr +creation_date: 2016-01-07T11:15:39Z + +[Term] +id: GO:0097699 +name: vascular endothelial cell response to fluid shear stress +namespace: biological_process +def: "Any response to fluid shear stress in a vascular endothelial cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +synonym: "blood vessel endothelial cell response to fluid shear stress" EXACT [] +is_a: GO:0071498 ! cellular response to fluid shear stress +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2016-01-27T12:37:32Z + +[Term] +id: GO:0097700 +name: vascular endothelial cell response to laminar fluid shear stress +namespace: biological_process +def: "Any response to laminar fluid shear stress in a vascular endothelial cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +synonym: "blood vessel endothelial cell response to laminar fluid shear stress" EXACT [] +is_a: GO:0071499 ! cellular response to laminar fluid shear stress +is_a: GO:0097699 ! vascular endothelial cell response to fluid shear stress +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2016-01-27T12:42:01Z + +[Term] +id: GO:0097701 +name: response to pulsatile fluid shear stress +namespace: biological_process +def: "Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +is_a: GO:0034405 ! response to fluid shear stress +created_by: pr +creation_date: 2016-01-27T14:13:31Z + +[Term] +id: GO:0097702 +name: response to oscillatory fluid shear stress +namespace: biological_process +def: "Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +is_a: GO:0034405 ! response to fluid shear stress +created_by: pr +creation_date: 2016-01-27T14:17:08Z + +[Term] +id: GO:0097703 +name: cellular response to pulsatile fluid shear stress +namespace: biological_process +def: "Any response to pulsatile fluid shear stress that occurs at the level of a cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +is_a: GO:0071498 ! cellular response to fluid shear stress +is_a: GO:0097701 ! response to pulsatile fluid shear stress +created_by: pr +creation_date: 2016-01-27T14:18:23Z + +[Term] +id: GO:0097704 +name: cellular response to oscillatory fluid shear stress +namespace: biological_process +def: "Any response to oscillatory fluid shear stress that occurs at the level of a cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +is_a: GO:0071498 ! cellular response to fluid shear stress +is_a: GO:0097702 ! response to oscillatory fluid shear stress +created_by: pr +creation_date: 2016-01-27T14:20:54Z + +[Term] +id: GO:0097705 +name: vascular endothelial cell response to pulsatile fluid shear stress +namespace: biological_process +def: "Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +synonym: "blood vessel endothelial cell response to pulsatile fluid shear stress" EXACT [] +is_a: GO:0097699 ! vascular endothelial cell response to fluid shear stress +is_a: GO:0097703 ! cellular response to pulsatile fluid shear stress +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2016-01-27T14:22:44Z + +[Term] +id: GO:0097706 +name: vascular endothelial cell response to oscillatory fluid shear stress +namespace: biological_process +def: "Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:21768538] +synonym: "blood vessel endothelial cell response to oscillatory fluid shear stress" EXACT [] +is_a: GO:0097699 ! vascular endothelial cell response to fluid shear stress +is_a: GO:0097704 ! cellular response to oscillatory fluid shear stress +property_value: RO:0002161 NCBITaxon:4751 +created_by: pr +creation_date: 2016-01-27T14:25:34Z + +[Term] +id: GO:0097707 +name: ferroptosis +namespace: biological_process +def: "A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes." [GOC:mtg_apoptosis, PMID:25236395, PMID:26794443] +synonym: "iron-dependent programmed cell death" RELATED [] +is_a: GO:0012501 ! programmed cell death +created_by: pr +creation_date: 2016-03-03T12:51:18Z + +[Term] +id: GO:0097708 +name: intracellular vesicle +namespace: cellular_component +def: "Any vesicle that is part of the intracellular region." [GOC:vesicles] +is_a: GO:0031982 ! vesicle +is_a: GO:0043229 ! intracellular organelle +intersection_of: GO:0031982 ! vesicle +intersection_of: part_of GO:0005622 ! intracellular +created_by: pr +creation_date: 2016-03-29T17:39:45Z + +[Term] +id: GO:0097709 +name: connective tissue replacement +namespace: biological_process +def: "The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared." [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:25590961] +is_a: GO:0048771 ! tissue remodeling +created_by: pr +creation_date: 2016-05-17T10:49:10Z + +[Term] +id: GO:0097710 +name: viral terminase, small subunit +namespace: cellular_component +def: "The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit." [GOC:ch, GOC:jh2, PMID:18687036] +comment: This term should only be used when the small subunit consists of more than one polypeptide. +synonym: "virus terminase, small subunit" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043493 ! viral terminase complex +created_by: pr +creation_date: 2016-06-07T12:45:00Z + +[Term] +id: GO:0097711 +name: ciliary basal body-plasma membrane docking +namespace: biological_process +def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235, Reactome:R-HSA-5620912.1] +comment: Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella. +synonym: "anchoring of the basal body to the plasma membrane" RELATED [] +synonym: "ciliary basal body docking" EXACT [] +xref: Reactome:R-HSA-5620912.1 +is_a: GO:0140056 ! organelle localization by membrane tethering +relationship: part_of GO:0060271 ! cilium assembly +created_by: pr +creation_date: 2016-08-05T16:12:33Z + +[Term] +id: GO:0097712 +name: vesicle targeting, trans-Golgi to periciliary membrane compartment +namespace: biological_process +def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645, Reactome:R-HSA-5620920.1] +is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi +relationship: part_of GO:0060271 ! cilium assembly +created_by: pr +creation_date: 2016-08-05T16:16:28Z + +[Term] +id: GO:0097713 +name: dolichol-phosphate-mannose synthase regulator activity +namespace: molecular_function +def: "Binds to and modulates the activity of dolichol-phosphate-mannose synthase." [GOC:vw, PMID:10835346] +is_a: GO:0030234 ! enzyme regulator activity +created_by: pr +creation_date: 2016-08-23T11:19:37Z + +[Term] +id: GO:0097714 +name: response to viscosity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus." [GOC:sl, PMID:7061416] +is_a: GO:0009628 ! response to abiotic stimulus +created_by: pr +creation_date: 2016-08-23T14:32:46Z + +[Term] +id: GO:0097715 +name: cellular response to viscosity +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus." [GOC:sl, PMID:7061416] +is_a: GO:0071214 ! cellular response to abiotic stimulus +is_a: GO:0097714 ! response to viscosity +created_by: pr +creation_date: 2016-08-23T14:34:05Z + +[Term] +id: GO:0097716 +name: copper ion transport across blood-brain barrier +namespace: biological_process +def: "The directed movement of copper (Cu) ions passing through the blood-brain barrier." [GOC:sl, PMID:24614235] +synonym: "copper ion transport across BBB" RELATED [] +is_a: GO:0006825 ! copper ion transport +is_a: GO:0150104 ! transport across blood-brain barrier +created_by: pr +creation_date: 2016-08-23T14:35:54Z + +[Term] +id: GO:0097717 +name: copper ion transport across blood-cerebrospinal fluid barrier +namespace: biological_process +def: "The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier." [GOC:sl, PMID:24614235] +synonym: "copper ion transport across BCB" RELATED [] +synonym: "copper ion transport across BCSFB" EXACT [] +synonym: "copper ion transport across blood-CSF barrier" EXACT [] +synonym: "copper ion transport across blood/cerebrospinal fluid barrier" EXACT [] +synonym: "copper ion transport across blood/CSF barrier" EXACT [] +is_a: GO:0006825 ! copper ion transport +is_a: GO:0150195 ! transport across blood-cerebrospinal fluid barrier +created_by: pr +creation_date: 2016-08-23T14:37:33Z + +[Term] +id: GO:0097718 +name: disordered domain specific binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a disordered domain of a protein." [GOC:gg, PMID:11746698] +synonym: "disordered protein domain specific binding" RELATED [] +is_a: GO:0019904 ! protein domain specific binding +created_by: pr +creation_date: 2016-08-23T16:42:51Z + +[Term] +id: GO:0097719 +name: neural tissue regeneration +namespace: biological_process +def: "The regrowth of neural tissue following its loss or destruction." [Wikipedia:Neuroregeneration] +synonym: "neuroregeneration" RELATED [] +is_a: GO:0042246 ! tissue regeneration +created_by: pr +creation_date: 2016-08-25T13:14:27Z + +[Term] +id: GO:0097720 +name: calcineurin-mediated signaling +namespace: biological_process +def: "Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression." [GOC:di, PMID:25655284, PMID:25878052, PMID:26851544] +synonym: "calcineurin signaling" RELATED [] +synonym: "calcineurin-mediated signalling" EXACT [] +is_a: GO:0019722 ! calcium-mediated signaling +created_by: pr +creation_date: 2016-08-25T15:22:21Z + +[Term] +id: GO:0097721 +name: ciliary vesicle +namespace: cellular_component +def: "A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle." [GOC:cilia, PMID:13978319, PMID:25686250] +synonym: "CV" RELATED [PMID:2568625] +synonym: "primary ciliary vesicle" EXACT [PMID:20427320] +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: pr +creation_date: 2016-08-30T13:54:38Z + +[Term] +id: GO:0097722 +name: sperm motility +namespace: biological_process +def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc] +subset: gocheck_do_not_annotate +synonym: "sperm movement" EXACT [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0048870 ! cell motility +created_by: pr +creation_date: 2016-09-01T12:00:45Z + +[Term] +id: GO:0097723 +name: amoeboid sperm motility +namespace: biological_process +def: "Any process involved in the controlled movement of an amoeboid sperm cell." [GOC:cilia, GOC:krc] +synonym: "ameboid sperm motility" EXACT [] +synonym: "ameboid sperm movement" EXACT [] +synonym: "amoeboid sperm movement" EXACT [] +is_a: GO:0097722 ! sperm motility +created_by: pr +creation_date: 2016-09-01T12:02:19Z + +[Term] +id: GO:0097725 +name: histone H3-K79 dimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone." [GOC:hbye, PMID:27541139] +synonym: "histone H3 K79 dimethylation" EXACT [] +synonym: "histone lysine H3 K79 dimethylation" EXACT [] +is_a: GO:0018027 ! peptidyl-lysine dimethylation +is_a: GO:0034729 ! histone H3-K79 methylation +created_by: pr +creation_date: 2016-09-15T12:41:13Z + +[Term] +id: GO:0097726 +name: LEM domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF)." [GOC:rz, InterPro:IPR003887, PMID:22399800] +synonym: "lamina-associated polypeptide, emerin, MAN1 domain binding" EXACT [] +synonym: "LAP2, emerin, MAN1 domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding +created_by: pr +creation_date: 2016-09-19T10:19:02Z + +[Term] +id: GO:0097727 +name: blepharoplast +namespace: cellular_component +def: "An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell." [GOC:cilia, GOC:tb, PMID:22691130, PMID:25047614] +comment: The blepharoplast should not be confused with a basal body; rather, it acts as the precursor assembly zone for multiple basal bodies. +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +created_by: pr +creation_date: 2016-09-23T10:57:18Z + +[Term] +id: GO:0097728 +name: 9+0 motile cilium +namespace: cellular_component +def: "A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme)." [GOC:cilia, PMID:10330409, PMID:22118931] +comment: This type of cilia may be present in solitary (classic nodal cilia in embryonic nodes) or in multiple copies (e.g. in the choroid plexus epithelium). +synonym: "motile 9+0 cilium" EXACT [] +synonym: "nodal cilium" NARROW [] +is_a: GO:0031514 ! motile cilium +relationship: has_part GO:0036156 ! inner dynein arm +relationship: has_part GO:0036157 ! outer dynein arm +relationship: has_part GO:0097545 ! axonemal outer doublet +created_by: pr +creation_date: 2016-09-27T15:24:37Z + +[Term] +id: GO:0097729 +name: 9+2 motile cilium +namespace: cellular_component +def: "A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme)." [GOC:cilia, PMID:22118931] +comment: This type of cilia may be present in solitary (so-called flagella, e.g. in sperm) or in multiple copies (so-called conventional motile cilia, e.g. in tracheal epithelium, ependyma or oviduct epithelium). +synonym: "conventional motile cilium" NARROW [] +synonym: "motile 9+2 cilium" EXACT [] +synonym: "sperm flagellum" NARROW [] +is_a: GO:0031514 ! motile cilium +relationship: has_part GO:0036156 ! inner dynein arm +relationship: has_part GO:0036157 ! outer dynein arm +relationship: has_part GO:0097540 ! axonemal central pair +relationship: has_part GO:0097545 ! axonemal outer doublet +created_by: pr +creation_date: 2016-09-27T15:26:34Z + +[Term] +id: GO:0097730 +name: non-motile cilium +namespace: cellular_component +alt_id: GO:0031513 +def: "A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] +synonym: "immotile cilium" EXACT [] +synonym: "immotile primary cilium" RELATED [] +synonym: "nonmotile cilium" EXACT [] +synonym: "nonmotile primary cilia" RELATED [] +synonym: "nonmotile primary cilium" RELATED [] +synonym: "sensory cilium" RELATED [] +is_a: GO:0005929 ! cilium +created_by: pr +creation_date: 2016-09-29T14:02:11Z + +[Term] +id: GO:0097731 +name: 9+0 non-motile cilium +namespace: cellular_component +def: "A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme)." [GOC:cilia, PMID:22118931] +comment: This type of cilia may be present in solitary (authentic primary cilia in many cell types) or in multiple copies (e.g. in Grueneberg ganglion neurons). +synonym: "9+0 immotile cilium" EXACT [] +synonym: "non-motile 9+0 cilium" EXACT [] +synonym: "primary cilium" NARROW [] +is_a: GO:0097730 ! non-motile cilium +created_by: pr +creation_date: 2016-09-29T14:05:03Z + +[Term] +id: GO:0097732 +name: 9+2 non-motile cilium +namespace: cellular_component +def: "A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme)." [GOC:cilia, PMID:21307074, PMID:22118931] +comment: This type of cilia may be present in solitary (e.g. in inner hair cells) or in multiple copies (e.g. in olfactory neurons). +synonym: "9+2 immotile cilium" RELATED [] +synonym: "non-motile 9+2 cilium" EXACT [] +is_a: GO:0097730 ! non-motile cilium +relationship: has_part GO:0036157 ! outer dynein arm +created_by: pr +creation_date: 2016-09-29T14:07:33Z + +[Term] +id: GO:0097733 +name: photoreceptor cell cilium +namespace: cellular_component +def: "A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment." [GOC:cilia, Wikipedia:Photoreceptor_cell#Histology] +synonym: "photoreceptor cilium" EXACT [] +is_a: GO:0043005 ! neuron projection +is_a: GO:0097731 ! 9+0 non-motile cilium +created_by: pr +creation_date: 2016-09-30T10:50:11Z + +[Term] +id: GO:0097734 +name: extracellular exosome biogenesis +namespace: biological_process +def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495] +synonym: "exosome assembly or secretion" EXACT [] +synonym: "exosome biogenesis" EXACT [] +synonym: "exosome production" EXACT [] +synonym: "ILV assembly" RELATED [] +synonym: "intraluminal vesicle assembly" RELATED [] +is_a: GO:0140112 ! extracellular vesicle biogenesis +created_by: pr +creation_date: 2016-10-03T14:35:25Z + +[Term] +id: GO:0097735 +name: DIM/DIP cell wall layer +namespace: cellular_component +def: "A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds." [GOC:pr] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009275 ! Gram-positive-bacterium-type cell wall +created_by: pr +creation_date: 2016-10-05T14:55:30Z + +[Term] +id: GO:0097736 +name: aerial mycelium formation +namespace: biological_process +def: "The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae." [GOC:di, PMID:12832397] +synonym: "aerial hyphal growth" RELATED [] +synonym: "fertile mycelium formation" RELATED [] +is_a: GO:0019954 ! asexual reproduction +is_a: GO:0048856 ! anatomical structure development +created_by: pr +creation_date: 2016-10-14T14:25:22Z + +[Term] +id: GO:0097737 +name: acquisition of mycelium reproductive competence +namespace: biological_process +def: "A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium." [GOC:di, PMID:23864594] +synonym: "mycelium developmental competence" RELATED [] +is_a: GO:0032502 ! developmental process +created_by: pr +creation_date: 2016-10-14T16:36:09Z + +[Term] +id: GO:0097738 +name: substrate mycelium formation +namespace: biological_process +def: "The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate." [GOC:di, PMID:10021365] +is_a: GO:0019954 ! asexual reproduction +is_a: GO:0048856 ! anatomical structure development +created_by: pr +creation_date: 2016-10-18T16:21:05Z + +[Term] +id: GO:0097739 +name: negative regulation of ferrichrome biosynthetic process in response to iron +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus." [GOC:al] +is_a: GO:1905569 ! negative regulation of ferrichrome biosynthetic process +relationship: part_of GO:0071281 ! cellular response to iron ion +created_by: pr +creation_date: 2016-10-18T17:00:24Z + +[Term] +id: GO:0097740 +name: paraflagellar rod +namespace: cellular_component +def: "A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling." [GOC:cilia, PMID:19879876, PMID:26199333, PMID:26688619] +synonym: "PFR" RELATED [] +is_a: GO:0099080 ! supramolecular complex +relationship: part_of GO:0097729 ! 9+2 motile cilium +created_by: pr +creation_date: 2016-10-19T11:30:08Z + +[Term] +id: GO:0097741 +name: mastigoneme +namespace: cellular_component +def: "A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum." [GOC:cilia, PMID:943397, Wikipedia:Mastigoneme] +is_a: GO:0099080 ! supramolecular complex +relationship: part_of GO:0031514 ! motile cilium +created_by: pr +creation_date: 2016-10-19T11:33:38Z + +[Term] +id: GO:0097742 +name: de novo centriole assembly +namespace: biological_process +def: "Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects." [GOC:cilia, PMID:25047614, PMID:25291643] +synonym: "acentriolar basal body biogenesis" RELATED [] +synonym: "de novo basal body amplification" RELATED [] +synonym: "de novo basal body assembly" RELATED [] +synonym: "de novo basal body biogenesis" RELATED [] +synonym: "de novo basal body generation" RELATED [] +synonym: "de novo centriole amplification" RELATED [] +synonym: "de novo ciliary basal body assembly" RELATED [] +synonym: "multiciliation" RELATED [] +synonym: "multiciliogenesis" RELATED [] +is_a: GO:0098534 ! centriole assembly +created_by: pr +creation_date: 2016-10-19T15:13:50Z + +[Term] +id: GO:0097743 +name: de novo centriole assembly via blepharoplast +namespace: biological_process +def: "A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface." [GOC:cilia, PMID:25047614] +synonym: "multiciliation" RELATED [] +synonym: "multiciliogenesis" RELATED [] +is_a: GO:0097742 ! de novo centriole assembly +property_value: RO:0002161 NCBITaxon:3176 +property_value: RO:0002161 NCBITaxon:3312 +property_value: RO:0002161 NCBITaxon:3378 +property_value: RO:0002161 NCBITaxon:3398 +created_by: pr +creation_date: 2016-10-19T15:18:34Z + +[Term] +id: GO:0097744 +name: urate salt excretion +namespace: biological_process +def: "The elimination by an organism of urate salt or uric acid." [GOC:jl, Wikipedia:Uric_acid#Biology] +synonym: "urate excretion" BROAD [] +is_a: GO:0007588 ! excretion +created_by: pr +creation_date: 2016-10-27T11:35:59Z + +[Term] +id: GO:0097745 +name: mitochondrial tRNA 5'-end processing +namespace: biological_process +def: "The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion." [GOC:pf, PMID:21307182, PMID:26143376, PMID:27484477] +is_a: GO:0000964 ! mitochondrial RNA 5'-end processing +is_a: GO:0090646 ! mitochondrial tRNA processing +is_a: GO:0099116 ! tRNA 5'-end processing +created_by: pr +creation_date: 2016-11-08T10:50:51Z + +[Term] +id: GO:0097746 +name: regulation of blood vessel diameter +namespace: biological_process +alt_id: GO:0042312 +alt_id: GO:0050880 +def: "Any process that modulates the diameter of blood vessels." [GOC:pr] +synonym: "regulation of blood vessel size" RELATED [] +synonym: "regulation of vasodilatation" RELATED [] +synonym: "regulation of vasodilation" RELATED [] +is_a: GO:0003018 ! vascular process in circulatory system +is_a: GO:0035296 ! regulation of tube diameter +relationship: part_of GO:0008015 ! blood circulation +created_by: pr +creation_date: 2016-11-24T15:45:05Z + +[Term] +id: GO:0097747 +name: RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template." [GOC:pf] +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: pr +creation_date: 2016-12-02T11:48:55Z + +[Term] +id: GO:0097748 +name: 3'-5' RNA polymerase activity +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end." [GOC:pf, PMID:22456265, PMID:27484477] +xref: RHEA:57528 +is_a: GO:0097747 ! RNA polymerase activity +created_by: pr +creation_date: 2016-12-02T11:51:31Z + +[Term] +id: GO:0097749 +name: membrane tubulation +namespace: biological_process +def: "A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules)." [GOC:pr] +is_a: GO:0061024 ! membrane organization +created_by: pr +creation_date: 2016-12-21T12:32:24Z + +[Term] +id: GO:0097750 +name: endosome membrane tubulation +namespace: biological_process +def: "A membrane tubulation process occurring in an endosome membrane." [GOC:bc, GOC:PARL, PMID:26911690] +synonym: "endosomal membrane tubulation" EXACT [] +is_a: GO:0007032 ! endosome organization +is_a: GO:0097749 ! membrane tubulation +created_by: pr +creation_date: 2016-12-21T12:33:09Z + +[Term] +id: GO:0097751 +name: spore-bearing structure formation +namespace: biological_process +def: "The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores." [GOC:di] +synonym: "sporangium formation" BROAD [] +synonym: "sporophore formation" EXACT [] +is_a: GO:0003006 ! developmental process involved in reproduction +relationship: part_of GO:0075259 ! spore-bearing structure development +created_by: pr +creation_date: 2017-01-11T13:55:24Z + +[Term] +id: GO:0097752 +name: regulation of DNA stability +namespace: biological_process +def: "Any process that modulates the stability of DNA." [GOC:pr] +is_a: GO:0065008 ! regulation of biological quality +created_by: pr +creation_date: 2017-01-24T11:23:01Z + +[Term] +id: GO:0097753 +name: membrane bending +namespace: biological_process +def: "A membrane organization process resulting in the bending of a membrane." [GOC:krc, GOC:pr, GOC:vw, Wikipedia:Membrane_curvature] +synonym: "membrane curvature" RELATED [] +is_a: GO:0061024 ! membrane organization +created_by: pr +creation_date: 2017-01-25T16:37:06Z + +[Term] +id: GO:0097754 +name: clathrin-mediated membrane bending +namespace: biological_process +def: "A membrane bending process mediated by clathrin." [GOC:pr, Wikipedia:Membrane_curvature] +is_a: GO:0097753 ! membrane bending +relationship: has_part GO:0048268 ! clathrin coat assembly +created_by: pr +creation_date: 2017-01-25T16:38:42Z + +[Term] +id: GO:0097755 +name: positive regulation of blood vessel diameter +namespace: biological_process +alt_id: GO:0045909 +def: "Any process that increases the diameter of blood vessels." [GOC:pr] +synonym: "positive regulation of vasodilation" RELATED [] +is_a: GO:0097746 ! regulation of blood vessel diameter +created_by: pr +creation_date: 2017-02-08T15:33:21Z + +[Term] +id: GO:0097756 +name: negative regulation of blood vessel diameter +namespace: biological_process +alt_id: GO:0045908 +def: "Any process that decreases the diameter of blood vessels." [GOC:pr] +synonym: "negative regulation of vasodilation" RELATED [] +is_a: GO:0097746 ! regulation of blood vessel diameter +created_by: pr +creation_date: 2017-02-08T15:36:16Z + +[Term] +id: GO:0098001 +name: receptor-mediated bacteriophage reversible attachment to host cell +namespace: biological_process +def: "Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection." [GOC:bm] +comment: This process was historically defined by the release, by Waring blending or sonication, by dilution and centrifugation, or by filtration and washing, of infective virions from their complexes with cells, thus contrary to what is observed after irreversible adsorption. +synonym: "phage reversible adsorption" RELATED [GOC:bm] +synonym: "reversible bacteriophage attachment, binding of host cell surface receptor" EXACT [GOC:bf, GOC:jl] +is_a: GO:0098671 ! adhesion receptor-mediated virion attachment to host cell +created_by: bm + +[Term] +id: GO:0098002 +name: receptor-mediated bacteriophage irreversible attachment to host cell +namespace: biological_process +def: "The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell." [GOC:bm] +synonym: "irreversible bacteriophage attachment, binding of host cell surface receptor" EXACT [GOC:bf, GOC:jl] +synonym: "phage irreversible adsorption" RELATED [GOC:bm] +is_a: GO:0098670 ! entry receptor-mediated virion attachment to host cell +created_by: bm + +[Term] +id: GO:0098003 +name: viral tail assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a virus tail." [GOC:bm] +synonym: "bacteriophage tail assembly" NARROW [GOC:bm] +synonym: "virus tail assembly" EXACT [GOC:bf, GOC:jl] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly +created_by: bm +creation_date: 2012-07-18T16:01:59Z + +[Term] +id: GO:0098004 +name: virus tail fiber assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber." [GOC:bm] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0098003 ! viral tail assembly +created_by: bm +creation_date: 2012-07-18T16:08:15Z + +[Term] +id: GO:0098005 +name: viral head-tail joining +namespace: biological_process +def: "Process by which virus heads and tails are attached to each other." [GOC:bm] +synonym: "phage head tail joining" NARROW [GOC:bm] +synonym: "virus head-tail joining" EXACT [GOC:bf, GOC:jl] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019068 ! virion assembly +created_by: bm +creation_date: 2012-07-18T16:11:59Z + +[Term] +id: GO:0098006 +name: viral DNA genome packaging, headful +namespace: biological_process +def: "The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full." [GOC:bm] +comment: Generalized transducing phages usually use this mode of DNA packaging. +synonym: "phage headful packaging" NARROW [GOC:bm] +is_a: GO:0019073 ! viral DNA genome packaging +created_by: bm +creation_date: 2012-07-18T16:15:09Z + +[Term] +id: GO:0098009 +name: viral terminase, large subunit +namespace: cellular_component +def: "The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit." [GOC:bm, GOC:ch, GOC:jh2, PMID:18687036] +comment: This term should only be used when the large subunit consists of more than one polypeptide. +synonym: "virus terminase, large subunit" EXACT [] +is_a: GO:1904949 ! ATPase complex +relationship: part_of GO:0043493 ! viral terminase complex +created_by: bm +creation_date: 2012-07-25T10:13:00Z + +[Term] +id: GO:0098015 +name: virus tail +namespace: cellular_component +def: "Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell." [GOC:bm] +comment: Many bacteriophages with dsDNA genomes, or Caudovirales, have a tail. The viral tail can be short (Podoviridae), long and non-contractile (Siphoviridae) or long and contractile (Myoviridae). The tail is the channel through which the phage genome is injected into the host bacterial cell. +synonym: "bacteriophage tail" NARROW [GOC:bm] +synonym: "viral tail" RELATED [GOC:bf] +is_a: GO:0044423 ! virion part +created_by: bm +creation_date: 2012-07-18T17:04:46Z + +[Term] +id: GO:0098017 +name: viral capsid, major subunit +namespace: cellular_component +def: "The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits." [GOC:bm] +synonym: "major capsomere" EXACT [GOC:bf, GOC:bm, GOC:jl] +synonym: "major head protein" RELATED [] +is_a: GO:0046727 ! capsomere +created_by: bm +creation_date: 2012-07-19T11:21:21Z + +[Term] +id: GO:0098018 +name: viral capsid, minor subunit +namespace: cellular_component +def: "The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits." [GOC:bm] +synonym: "minor capsomere" EXACT [GOC:bf, GOC:bm, GOC:jl] +synonym: "minor head protein" RELATED [] +is_a: GO:0046727 ! capsomere +created_by: bm +creation_date: 2012-07-19T11:28:18Z + +[Term] +id: GO:0098019 +name: obsolete virus tail, major subunit +namespace: cellular_component +def: "OBSOLETE. The part of the viral tail that comprises the most common subunit type." [GOC:bm] +comment: The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages. +synonym: "major tail protein" RELATED [] +is_obsolete: true +created_by: bm +creation_date: 2012-07-19T11:32:55Z + +[Term] +id: GO:0098020 +name: obsolete virus tail, minor subunit +namespace: cellular_component +def: "OBSOLETE. The part of the viral tail that comprises the least common subunit type." [GOC:bm] +comment: The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages. +synonym: "bacteriophage minor protein subunit" NARROW [GOC:bm] +synonym: "minor tail protein" RELATED [GOC:bm] +is_obsolete: true +created_by: bm +creation_date: 2012-07-19T11:36:25Z + +[Term] +id: GO:0098021 +name: viral capsid, decoration +namespace: cellular_component +def: "Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential." [GOC:bm] +synonym: "decoration protein" RELATED [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019028 ! viral capsid +created_by: bm +creation_date: 2012-07-19T11:52:53Z + +[Term] +id: GO:0098022 +name: viral capsid, fiber +namespace: cellular_component +def: "A type of capsid decoration composed of fiber structures." [GOC:bm] +synonym: "head/capsid fiber" RELATED [GOC:bm] +is_a: GO:0098021 ! viral capsid, decoration +created_by: bm +creation_date: 2012-07-19T11:56:32Z + +[Term] +id: GO:0098023 +name: virus tail, tip +namespace: cellular_component +def: "The basal end of the virus tail, which is used by the virus to attach to the host cell." [GOC:bm] +synonym: "bacteriophage tail tip" NARROW [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:13:02Z + +[Term] +id: GO:0098024 +name: virus tail, fiber +namespace: cellular_component +def: "The fibrous region of the virus tail used to scan, recognize and attach to the host cell." [GOC:bm] +comment: For tailed bacteriophages, fibers typically bind to particular Lipopolysaccharide (LPS), polysaccharide or protein receptors on the cell surface. +synonym: "bacteriophage tail fiber" NARROW [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:14:50Z + +[Term] +id: GO:0098025 +name: virus tail, baseplate +namespace: cellular_component +def: "Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached." [GOC:bm] +comment: Tail fibers are often attached to the baseplate of Caudovirales (tailed bacteriophages with dsDNA genomes). Sometimes referred to as the tail tip or tip structure in Siphoviridae. +synonym: "bacteriophage baseplate" NARROW [GOC:bm] +synonym: "tail structure" RELATED [GOC:bm] +synonym: "tail tip" RELATED [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:16:51Z + +[Term] +id: GO:0098026 +name: virus tail, tube +namespace: cellular_component +def: "The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm." [GOC:bm] +comment: Applies in particular the Myoviridae bacteriophages. +synonym: "bacteriophage tail tube" NARROW [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:21:28Z + +[Term] +id: GO:0098027 +name: virus tail, sheath +namespace: cellular_component +def: "The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm." [GOC:bm] +synonym: "bacteriophage tail sheath" NARROW [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:23:27Z + +[Term] +id: GO:0098028 +name: virus tail, shaft +namespace: cellular_component +def: "The tube of the non-contractile tails of some viruses." [GOC:bm] +comment: This term applies in particular to the Siphoviridae bacteriophages, where the shaft is the channel for DNA translocation into the host cytoplasm. +synonym: "bacteriophage tail shaft" NARROW [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0098015 ! virus tail +created_by: bm +creation_date: 2012-07-19T14:24:28Z + +[Term] +id: GO:0098029 +name: icosahedral viral capsid, spike +namespace: cellular_component +def: "A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell." [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bm +creation_date: 2012-07-19T14:37:11Z + +[Term] +id: GO:0098030 +name: icosahedral viral capsid, neck +namespace: cellular_component +def: "A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae)." [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bm +creation_date: 2012-07-19T14:56:28Z + +[Term] +id: GO:0098031 +name: icosahedral viral capsid, collar +namespace: cellular_component +def: "A small disk located at the base of some icosahedral virus capsids." [GOC:bm] +is_a: GO:0044423 ! virion part +relationship: part_of GO:0019030 ! icosahedral viral capsid +created_by: bm +creation_date: 2012-07-19T15:01:12Z + +[Term] +id: GO:0098032 +name: icosahedral viral capsid, collar fiber +namespace: cellular_component +def: "A fiber attached to the collar structure of some icosahedral viral capsids." [GOC:bm] +is_a: GO:0098022 ! viral capsid, fiber +relationship: part_of GO:0098031 ! icosahedral viral capsid, collar +created_by: bm +creation_date: 2012-07-19T15:05:16Z + +[Term] +id: GO:0098033 +name: icosahedral viral capsid, neck fiber +namespace: cellular_component +def: "A fiber attached to the neck at the base of some icosahedral viral capsids." [GOC:bm] +is_a: GO:0098022 ! viral capsid, fiber +relationship: part_of GO:0098030 ! icosahedral viral capsid, neck +created_by: bm +creation_date: 2012-07-19T15:07:39Z + +[Term] +id: GO:0098035 +name: viral DNA genome packaging via site-specific sequence recognition +namespace: biological_process +def: "The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase." [GOC:bm] +is_a: GO:0019073 ! viral DNA genome packaging +relationship: has_part GO:0019071 ! viral DNA cleavage involved in viral genome maturation +created_by: bm +creation_date: 2012-07-20T11:36:49Z + +[Term] +id: GO:0098036 +name: viral DNA genome packaging, 3' extended cos packaging +namespace: biological_process +def: "The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends." [GOC:bm] +is_a: GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +created_by: bm +creation_date: 2012-07-20T11:38:40Z + +[Term] +id: GO:0098037 +name: viral DNA genome packaging, 5' extended cos packaging +namespace: biological_process +def: "The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends." [GOC:bm] +is_a: GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +created_by: bm +creation_date: 2012-07-20T11:40:47Z + +[Term] +id: GO:0098038 +name: non-replicative transposition, DNA-mediated +namespace: biological_process +def: "Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition." [GOC:bm, PMID:2553270] +synonym: "cut-and-paste transposition" EXACT [GOC:bm] +is_a: GO:0006313 ! transposition, DNA-mediated +created_by: bm +creation_date: 2012-07-20T16:47:50Z + +[Term] +id: GO:0098039 +name: replicative transposition, DNA-mediated +namespace: biological_process +def: "Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition." [GOC:bm, PMID:10540284] +synonym: "copy-and-paste transposition" EXACT [GOC:bm] +synonym: "transpositional DNA genome replication" EXACT [] +is_a: GO:0006313 ! transposition, DNA-mediated +relationship: has_part GO:0006260 ! DNA replication +created_by: bm +creation_date: 2012-07-20T16:52:02Z + +[Term] +id: GO:0098045 +name: virus baseplate assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a virus baseplate." [GOC:bm] +is_a: GO:0016032 ! viral process +relationship: part_of GO:0098003 ! viral tail assembly +created_by: bm +creation_date: 2012-07-25T14:50:32Z + +[Term] +id: GO:0098046 +name: type V protein secretion system complex +namespace: cellular_component +def: "A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc)." [GOC:bf, GOC:bhm, PMID:15119822, PMID:15590781] +comment: Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'. +synonym: "autotransporter system complex" NARROW [PMID:15590781, Wikipedia:Secretion] +synonym: "T5SS complex" EXACT [Wikipedia:Secretion] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2012-08-01T10:05:49Z + +[Term] +id: GO:0098061 +name: viral capsid, internal space +namespace: cellular_component +def: "The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins." [GOC:bm] +synonym: "internal head protein" EXACT [GOC:bm] +is_a: GO:0044423 ! virion part +created_by: bm +creation_date: 2012-08-01T12:12:47Z + +[Term] +id: GO:0098501 +name: polynucleotide dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from a polynucleotide." [GOC:DOS] +is_a: GO:0006139 ! nucleobase-containing compound metabolic process +is_a: GO:0016311 ! dephosphorylation +is_a: GO:0043170 ! macromolecule metabolic process +created_by: dos +creation_date: 2013-09-18T14:49:10Z + +[Term] +id: GO:0098502 +name: DNA dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from a DNA molecule." [GOC:DOS] +is_a: GO:0016311 ! dephosphorylation +created_by: dos +creation_date: 2013-09-18T14:50:16Z + +[Term] +id: GO:0098503 +name: obsolete DNA 3' dephosphorylation +namespace: biological_process +def: "OBSOLETE. The process of removing a 3' phosphate group from a DNA molecule." [GOC:DOS] +comment: This term was obsoleted because it represents a molecular function, and not a specific coordinated process. +is_obsolete: true +created_by: dos +creation_date: 2013-09-18T14:51:17Z + +[Term] +id: GO:0098504 +name: obsolete DNA 3' dephosphorylation involved in DNA repair +namespace: biological_process +def: "OBSOLETE. Any 3' DNA dephosphorylation that is involved in the process of DNA repair." [GOC:DOS, PMID:11729194] +comment: This term was obsoleted because it represents a molecular function, and not a specific coordinated process. +is_obsolete: true +created_by: dos +creation_date: 2013-09-18T14:52:15Z + +[Term] +id: GO:0098505 +name: G-rich strand telomeric DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA." [PMID:11349150] +is_a: GO:0043047 ! single-stranded telomeric DNA binding +created_by: dos +creation_date: 2013-09-23T13:16:24Z + +[Term] +id: GO:0098506 +name: polynucleotide 3' dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from the 3' end of a polynucleotide." [GOC:dos] +is_a: GO:0016311 ! dephosphorylation + +[Term] +id: GO:0098507 +name: polynucleotide 5' dephosphorylation +namespace: biological_process +def: "The process of removing one or more phosphate groups from the 5' end of a polynucleotide." [GOC:dos] +is_a: GO:0016311 ! dephosphorylation + +[Term] +id: GO:0098508 +name: endothelial to hematopoietic transition +namespace: biological_process +def: "The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium." [PMID:20154732, PMID:22521721] +is_a: GO:0000904 ! cell morphogenesis involved in differentiation +is_a: GO:0060232 ! delamination +created_by: dos +creation_date: 2013-09-24T15:20:39Z + +[Term] +id: GO:0098509 +name: sensory perception of humidity +namespace: biological_process +def: "The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process." [PMID:18269908, PMID:8650222] +comment: Note, this is not classified under 'detection of chemical stimulus' as there are various potential mechanisms of hygroperception including detection of mechanical stimulus. +synonym: "hygrosensory perception" EXACT [PMID:8650222] +is_a: GO:0007600 ! sensory perception +created_by: dos +creation_date: 2013-09-25T13:52:27Z + +[Term] +id: GO:0098510 +name: sensory perception of high humidity +namespace: biological_process +def: "The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process." [PMID:18269908] +is_a: GO:0098509 ! sensory perception of humidity +created_by: dos +creation_date: 2013-09-25T13:57:27Z + +[Term] +id: GO:0098511 +name: sensory perception of low humidity +namespace: biological_process +def: "The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process." [PMID:18269908] +is_a: GO:0098509 ! sensory perception of humidity +created_by: dos +creation_date: 2013-09-25T14:02:02Z + +[Term] +id: GO:0098512 +name: detection of humidity stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity." [GOC:dos, PMID:8650222] +is_a: GO:0050906 ! detection of stimulus involved in sensory perception +is_a: GO:0098513 ! detection of humidity +intersection_of: GO:0098513 ! detection of humidity +intersection_of: part_of GO:0098509 ! sensory perception of humidity +relationship: part_of GO:0098509 ! sensory perception of humidity +created_by: dos +creation_date: 2013-09-25T14:09:25Z + +[Term] +id: GO:0098513 +name: detection of humidity +namespace: biological_process +def: "The series of events in which a humidity stimulus is received and converted into a molecular signal." [GOC:dos] +is_a: GO:0009581 ! detection of external stimulus +is_a: GO:0009582 ! detection of abiotic stimulus +created_by: dos +creation_date: 2013-09-25T14:11:13Z + +[Term] +id: GO:0098514 +name: detection of high humidity stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity." [GOC:dos, PMID:18269908] +is_a: GO:0098512 ! detection of humidity stimulus involved in sensory perception +is_a: GO:0098516 ! detection of high humidity +intersection_of: GO:0098516 ! detection of high humidity +intersection_of: part_of GO:0098510 ! sensory perception of high humidity +relationship: part_of GO:0098510 ! sensory perception of high humidity +created_by: dos +creation_date: 2013-09-25T14:20:54Z + +[Term] +id: GO:0098515 +name: detection of low humidity stimulus involved in sensory perception +namespace: biological_process +def: "The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity." [GOC:dos, PMID:18269908] +is_a: GO:0098512 ! detection of humidity stimulus involved in sensory perception +is_a: GO:0098517 ! detection of low humidity +intersection_of: GO:0098517 ! detection of low humidity +intersection_of: part_of GO:0098511 ! sensory perception of low humidity +relationship: part_of GO:0098511 ! sensory perception of low humidity +created_by: dos +creation_date: 2013-09-25T14:24:29Z + +[Term] +id: GO:0098516 +name: detection of high humidity +namespace: biological_process +def: "The series of events in which high humidity is detected and converted into a molecular signal." [GOC:dos] +is_a: GO:0098513 ! detection of humidity +created_by: dos +creation_date: 2013-09-25T14:26:47Z + +[Term] +id: GO:0098517 +name: detection of low humidity +namespace: biological_process +def: "The series of events in which low humidity is detected and converted into a molecular signal." [GOC:dos] +is_a: GO:0098513 ! detection of humidity +created_by: dos +creation_date: 2013-09-25T14:27:18Z + +[Term] +id: GO:0098518 +name: polynucleotide phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate." [GOC:mah] +is_a: GO:0016791 ! phosphatase activity +relationship: part_of GO:0098501 ! polynucleotide dephosphorylation +created_by: dos +creation_date: 2013-09-26T11:02:35Z + +[Term] +id: GO:0098519 +name: nucleotide phosphatase activity, acting on free nucleotides +namespace: molecular_function +def: "Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate." [GOC:dos] +comment: To be used for NTP->NDP or NDP -> NMP. For nucleotide -> nucleoside (all phosphates removed) use nucleotidase. +synonym: "nucleotide phosphatase activity" EXACT [] +is_a: GO:0016791 ! phosphatase activity +created_by: dos +creation_date: 2013-09-26T11:04:45Z + +[Term] +id: GO:0098520 +name: excitatory neuromuscular junction +namespace: cellular_component +def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction." [GOC:dos] +is_a: GO:0031594 ! neuromuscular junction +is_a: GO:0060076 ! excitatory synapse +created_by: dos +creation_date: 2013-10-14T12:02:51Z + +[Term] +id: GO:0098521 +name: inhibitory neuromuscular junction +namespace: cellular_component +def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction." [GOC:dos] +comment: Inhibitory neuromuscular junctions are found in arthropods but not in vertebrates. +is_a: GO:0031594 ! neuromuscular junction +is_a: GO:0060077 ! inhibitory synapse +property_value: RO:0002161 NCBITaxon:7742 +created_by: dos +creation_date: 2013-10-14T12:04:08Z + +[Term] +id: GO:0098522 +name: neuromuscular junction of skeletal muscle fiber +namespace: cellular_component +def: "A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber." [GOC:dos] +comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT. +is_a: GO:0098520 ! excitatory neuromuscular junction +is_a: GO:0098523 ! neuromuscular junction of myotube +is_a: GO:0098981 ! cholinergic synapse +created_by: dos +creation_date: 2013-10-14T12:04:32Z + +[Term] +id: GO:0098523 +name: neuromuscular junction of myotube +namespace: cellular_component +def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos] +comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes. +is_a: GO:0031594 ! neuromuscular junction +created_by: dos +creation_date: 2013-10-14T12:05:12Z + +[Term] +id: GO:0098524 +name: neuromuscular junction of somatic muscle myotube +namespace: cellular_component +def: "A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell." [GOC:dos] +is_a: GO:0098523 ! neuromuscular junction of myotube +is_a: GO:0098527 ! neuromuscular junction of somatic muscle +created_by: dos +creation_date: 2013-10-14T12:05:43Z + +[Term] +id: GO:0098525 +name: excitatory neuromuscular junction of somatic myotube +namespace: cellular_component +def: "A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells." [GOC:dos] +is_a: GO:0098520 ! excitatory neuromuscular junction +is_a: GO:0098524 ! neuromuscular junction of somatic muscle myotube +created_by: dos +creation_date: 2013-10-14T12:06:08Z + +[Term] +id: GO:0098526 +name: inhibitory neuromuscular junction of somatic myotube +namespace: cellular_component +def: "A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods." [GOC:dos] +is_a: GO:0098521 ! inhibitory neuromuscular junction +is_a: GO:0098524 ! neuromuscular junction of somatic muscle myotube +created_by: dos +creation_date: 2013-10-14T12:06:43Z + +[Term] +id: GO:0098527 +name: neuromuscular junction of somatic muscle +namespace: cellular_component +def: "A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods." [GOC:dos] +is_a: GO:0031594 ! neuromuscular junction +created_by: dos +creation_date: 2013-10-14T12:07:05Z + +[Term] +id: GO:0098528 +name: skeletal muscle fiber differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos] +is_a: GO:0014902 ! myotube differentiation +is_a: GO:0035914 ! skeletal muscle cell differentiation +created_by: dos +creation_date: 2013-10-15T14:00:34Z + +[Term] +id: GO:0098529 +name: neuromuscular junction development, skeletal muscle fiber +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber." [GOC:mtg_OBO2OWL_2013] +is_a: GO:0007528 ! neuromuscular junction development +relationship: part_of GO:0048741 ! skeletal muscle fiber development + +[Term] +id: GO:0098530 +name: positive regulation of strand invasion +namespace: biological_process +def: "Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules." [GOC:dos, GOC:dph, GOC:elh, GOC:tb] +synonym: "positive regulation of D-loop biosynthesis" RELATED [GOC:elh] +synonym: "positive regulation of D-loop formation" RELATED [GOC:elh] +synonym: "positive regulation of Rad51-mediated strand invasion" EXACT [GOC:elh] +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:0060542 ! regulation of strand invasion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042148 ! strand invasion +relationship: positively_regulates GO:0042148 ! strand invasion +created_by: dos +creation_date: 2013-10-16T12:15:59Z + +[Term] +id: GO:0098531 +name: ligand-activated transcription factor activity +namespace: molecular_function +def: "A DNA-binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors." [GOC:dos, http://www.ecocyc.org/ECOLI/NEW-IMAGE?object=BC-3.1.2.3] +synonym: "direct ligand regulated sequence-specific DNA binding transcription factor activity" EXACT [] +synonym: "transcription factor activity, direct ligand regulated sequence-specific DNA binding" EXACT [] +is_a: GO:0003700 ! DNA-binding transcription factor activity +created_by: dos +creation_date: 2013-10-17T15:51:30Z + +[Term] +id: GO:0098532 +name: histone H3-K27 trimethylation +namespace: biological_process +def: "The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone." [PMID:19270745] +is_a: GO:0070734 ! histone H3-K27 methylation +created_by: dos +creation_date: 2013-10-18T14:11:17Z + +[Term] +id: GO:0098533 +name: ATPase dependent transmembrane transport complex +namespace: cellular_component +def: "A transmembrane protein complex that functions in ATPase dependent active transport across a membrane." [GOC:dos] +comment: The location of this complex is implicit in its activity, so its location is asserted as a regular relationship rather than as a part of an intersection. +is_a: GO:1902495 ! transmembrane transporter complex +created_by: dos +creation_date: 2013-10-22T12:12:52Z + +[Term] +id: GO:0098534 +name: centriole assembly +namespace: biological_process +def: "A cellular process that results in the assembly of one or more centrioles." [GOC:dos, PMID:24075808] +is_a: GO:0031023 ! microtubule organizing center organization +is_a: GO:0070925 ! organelle assembly +created_by: dos +creation_date: 2013-10-22T15:55:22Z + +[Term] +id: GO:0098535 +name: de novo centriole assembly involved in multi-ciliated epithelial cell differentiation +namespace: biological_process +def: "Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation." [GOC:cilia, GOC:dos, PMID:24075808, PMID:5111878, PMID:5661997] +comment: In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. +synonym: "centriole amplification" RELATED [PMID:24075808] +synonym: "de novo centriole assembly" BROAD [] +synonym: "de novo centriole assembly via deuterosome" EXACT [] +synonym: "deuterosomal basal body biogenesis" RELATED [] +synonym: "deuterosome pathway" RELATED [PMID:25047614] +synonym: "deuterosome-mediated centriole biogenesis" RELATED [PMID:24075808] +synonym: "multiciliation" RELATED [] +synonym: "multiciliogenesis" RELATED [] +is_a: GO:0097742 ! de novo centriole assembly +intersection_of: GO:0097742 ! de novo centriole assembly +intersection_of: part_of GO:1903251 ! multi-ciliated epithelial cell differentiation +relationship: part_of GO:1903251 ! multi-ciliated epithelial cell differentiation +created_by: dos +creation_date: 2013-10-22T16:03:13Z + +[Term] +id: GO:0098536 +name: deuterosome +namespace: cellular_component +def: "A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles." [GOC:cilia, GOC:dos, PMID:24075808, PMID:25047614, PMID:5661997] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +created_by: dos +creation_date: 2013-10-22T16:21:19Z + +[Term] +id: GO:0098537 +name: lobed nucleus +namespace: cellular_component +def: "Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans." [GOC:dos, GOC:tfm] +is_a: GO:0005634 ! nucleus +created_by: dos +creation_date: 2013-10-22T18:31:36Z + +[Term] +id: GO:0098538 +name: lumenal side of transport vesicle membrane +namespace: cellular_component +def: "The side (leaflet) of the transport vesicle membrane that faces the lumen." [GOC:ab] +synonym: "internal side of transport vesicle membrane" EXACT [] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0030658 ! transport vesicle membrane +created_by: dos +creation_date: 2013-10-24T11:43:55Z + +[Term] +id: GO:0098539 +name: cytoplasmic side of transport vesicle membrane +namespace: cellular_component +def: "The side (leaflet) of the transport vesicle membrane that faces the cytoplasm." [GOC:ab] +synonym: "external side of transport vesicle membrane" EXACT [] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0030658 ! transport vesicle membrane +created_by: dos +creation_date: 2013-10-24T11:48:07Z + +[Term] +id: GO:0098540 +name: lumenal side of trans-Golgi network transport vesicle membrane +namespace: cellular_component +def: "The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen." [GOC:ab] +synonym: "internal side of trans-Golgi network transport vesicle membrane" RELATED [] +is_a: GO:0098538 ! lumenal side of transport vesicle membrane +relationship: part_of GO:0012510 ! trans-Golgi network transport vesicle membrane +created_by: dos +creation_date: 2013-10-24T11:55:02Z + +[Term] +id: GO:0098541 +name: cytoplasmic side of trans-Golgi network transport vesicle membrane +namespace: cellular_component +def: "The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm." [GOC:ab] +synonym: "external side of trans-Golgi network transport vesicle membrane" EXACT [] +is_a: GO:0098539 ! cytoplasmic side of transport vesicle membrane +relationship: part_of GO:0012510 ! trans-Golgi network transport vesicle membrane +created_by: dos +creation_date: 2013-10-24T11:56:30Z + +[Term] +id: GO:0098542 +name: defense response to other organism +namespace: biological_process +def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] +is_a: GO:0006952 ! defense response +is_a: GO:0051707 ! response to other organism +created_by: dos +creation_date: 2013-11-11T12:59:11Z + +[Term] +id: GO:0098543 +name: detection of other organism +namespace: biological_process +alt_id: GO:0051824 +def: "The series of events in which a stimulus from another organism is received and converted into a molecular signal." [GOC:dos] +synonym: "recognition of other organism during symbiotic interaction" NARROW [GOC:dph] +synonym: "recognition of other organism involved in symbiotic interaction" NARROW [] +is_a: GO:0051707 ! response to other organism +is_a: GO:0098581 ! detection of external biotic stimulus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17977 xsd:anyURI +created_by: dos +creation_date: 2013-11-11T14:28:54Z + +[Term] +id: GO:0098544 +name: maintenance of protein complex location +namespace: biological_process +def: "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away." [GOC:dos] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0051235 ! maintenance of location +created_by: dos +creation_date: 2013-11-15T18:20:16Z + +[Term] +id: GO:0098545 +name: maintenance of protein complex location in cytoplasm +namespace: biological_process +def: "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere." [GOC:dos] +is_a: GO:0051651 ! maintenance of location in cell +is_a: GO:0098544 ! maintenance of protein complex location +relationship: occurs_in GO:0005737 ! cytoplasm +created_by: dos +creation_date: 2013-11-15T20:49:15Z + +[Term] +id: GO:0098546 +name: 2',5-3',5'-cyclic GMP-AMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with c[G(2',5')pA(2',5')p], a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages." [GOC:dos, PMID:23910378] +synonym: "c[G(2',5')pA(3',5')p] binding" EXACT [PMID:23910378] +is_a: GO:0030551 ! cyclic nucleotide binding +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0032561 ! guanyl ribonucleotide binding +is_a: GO:0043168 ! anion binding +created_by: dos +creation_date: 2013-12-03T15:31:39Z + +[Term] +id: GO:0098547 +name: lumenal side of Golgi membrane +namespace: cellular_component +def: "The side of the Golgi membrane that faces the lumen." [GOC:ab, GOC:dos] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0000139 ! Golgi membrane +created_by: dos +creation_date: 2013-12-03T10:44:23Z + +[Term] +id: GO:0098548 +name: cytoplasmic side of Golgi membrane +namespace: cellular_component +def: "The side (leaflet) of the Golgi membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0000139 ! Golgi membrane +created_by: dos +creation_date: 2013-12-03T10:49:33Z + +[Term] +id: GO:0098549 +name: somatic ring canal +namespace: cellular_component +def: "A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects." [GOC:dos, PMID:22135360, PMID:670316] +is_a: GO:0045171 ! intercellular bridge + +[Term] +id: GO:0098550 +name: lumenal side of early endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the early endosome membrane that faces the lumen." [GOC:lr] +synonym: "internal leaflet of early endosome membrane" EXACT [GOC:ab] +synonym: "internal side of early endosome membrane" EXACT [] +is_a: GO:0098565 ! lumenal side of endosome membrane +relationship: part_of GO:0031901 ! early endosome membrane + +[Term] +id: GO:0098551 +name: lumenal side of late endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the late endosome membrane that faces the lumen." [GOC:lr] +synonym: "internal leaflet of late endosome membrane" EXACT [GOC:ab] +synonym: "internal side of late endosome membrane" EXACT [] +is_a: GO:0098565 ! lumenal side of endosome membrane +relationship: part_of GO:0031902 ! late endosome membrane + +[Term] +id: GO:0098552 +name: side of membrane +namespace: cellular_component +def: "A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface." [GOC:dos] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0097478 ! leaflet of membrane bilayer +relationship: part_of GO:0016020 ! membrane +created_by: dos +creation_date: 2013-12-03T11:28:04Z + +[Term] +id: GO:0098553 +name: lumenal side of endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the plasma membrane that faces the lumen." [GOC:ab, GOC:dos] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:08:37Z + +[Term] +id: GO:0098554 +name: cytoplasmic side of endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the plasma membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:09:47Z + +[Term] +id: GO:0098555 +name: lumenal side of rough endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen." [GOC:ab, GOC:dos] +is_a: GO:0098553 ! lumenal side of endoplasmic reticulum membrane +relationship: part_of GO:0030867 ! rough endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:13:24Z + +[Term] +id: GO:0098556 +name: cytoplasmic side of rough endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +is_a: GO:0098554 ! cytoplasmic side of endoplasmic reticulum membrane +relationship: part_of GO:0030867 ! rough endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:15:44Z + +[Term] +id: GO:0098557 +name: cytoplasmic side of smooth endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +is_a: GO:0098554 ! cytoplasmic side of endoplasmic reticulum membrane +relationship: part_of GO:0030868 ! smooth endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:17:58Z + +[Term] +id: GO:0098558 +name: lumenal side of smooth endoplasmic reticulum membrane +namespace: cellular_component +def: "The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen." [GOC:ab, GOC:dos] +is_a: GO:0098553 ! lumenal side of endoplasmic reticulum membrane +relationship: part_of GO:0030868 ! smooth endoplasmic reticulum membrane +created_by: dos +creation_date: 2013-12-03T12:19:28Z + +[Term] +id: GO:0098559 +name: cytoplasmic side of early endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the early endosome membrane that faces the cytoplasm." [GOC:lr] +comment: In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane. +synonym: "external leaflet of early endosome membrane" EXACT [GOC:ab] +synonym: "external side of early endosome membrane" EXACT [] +is_a: GO:0010009 ! cytoplasmic side of endosome membrane +relationship: part_of GO:0031901 ! early endosome membrane + +[Term] +id: GO:0098560 +name: cytoplasmic side of late endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the late endosome membrane that faces the cytoplasm." [GOC:lr] +comment: In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane. +synonym: "external leaflet of late endosome membrane" EXACT [GOC:ab] +synonym: "external side of late endosome membrane" EXACT [] +is_a: GO:0010009 ! cytoplasmic side of endosome membrane +relationship: part_of GO:0031902 ! late endosome membrane + +[Term] +id: GO:0098561 +name: methyl accepting chemotaxis protein complex +namespace: cellular_component +def: "A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus." [GOC:dos, PMID:1326408, PMID:15802240] +comment: A number of complexes of this class are found in E.coli. +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0098562 +name: cytoplasmic side of membrane +namespace: cellular_component +def: "The side of a membrane that faces the cytoplasm." [GOC:dos] +is_a: GO:0098552 ! side of membrane +created_by: dos +creation_date: 2013-12-12T11:21:30Z + +[Term] +id: GO:0098563 +name: intrinsic component of synaptic vesicle membrane +namespace: cellular_component +def: "The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0030672 ! synaptic vesicle membrane +relationship: part_of GO:0030672 ! synaptic vesicle membrane + +[Term] +id: GO:0098564 +name: trans-Golgi network transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed within the membrane of a trans-Golgi network transport vesicle." [GOC:dos] +is_a: GO:0005796 ! Golgi lumen +is_a: GO:0098566 ! transport vesicle lumen +relationship: part_of GO:0030140 ! trans-Golgi network transport vesicle + +[Term] +id: GO:0098565 +name: lumenal side of endosome membrane +namespace: cellular_component +def: "The side (leaflet) of the endosome membrane that faces the lumen." [GOC:dos] +synonym: "internal leaflet of endosome membrane" EXACT [GOC:ab] +synonym: "internal side of endosome membrane" EXACT [] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0010008 ! endosome membrane + +[Term] +id: GO:0098566 +name: transport vesicle lumen +namespace: cellular_component +def: "The volume enclosed within the membrane of a transport vesicle." [GOC:dos] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0030133 ! transport vesicle + +[Term] +id: GO:0098567 +name: periplasmic side of plasma membrane +namespace: cellular_component +def: "The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface." [GOC:dos] +is_a: GO:0009897 ! external side of plasma membrane +created_by: dos +creation_date: 2013-12-19T09:31:30Z + +[Term] +id: GO:0098568 +name: external side of mycolate outer membrane +namespace: cellular_component +def: "The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface." [GOC:dos, PMID:18316738, PMID:18567661] +is_a: GO:0031240 ! external side of cell outer membrane + +[Term] +id: GO:0098569 +name: internal side of mycolate outer membrane +namespace: cellular_component +def: "The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network." [GOC:dos, PMID:18316738, PMID:18567661] +is_a: GO:0098552 ! side of membrane + +[Term] +id: GO:0098570 +name: stromal side of plastid inner membrane +namespace: cellular_component +def: "The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface." [GOC:dos] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0009528 ! plastid inner membrane + +[Term] +id: GO:0098571 +name: lumenal side of plastid thylakoid membrane +namespace: cellular_component +def: "The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface." [GOC:dos] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0055035 ! plastid thylakoid membrane + +[Term] +id: GO:0098572 +name: stromal side of plastid thylakoid membrane +namespace: cellular_component +def: "The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface." [GOC:dos] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0055035 ! plastid thylakoid membrane + +[Term] +id: GO:0098573 +name: intrinsic component of mitochondrial membrane +namespace: cellular_component +def: "The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos] +synonym: "intrinsic to mitochondrial membrane" NARROW [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031966 ! mitochondrial membrane +relationship: part_of GO:0031966 ! mitochondrial membrane + +[Term] +id: GO:0098574 +name: cytoplasmic side of lysosomal membrane +namespace: cellular_component +def: "The side (leaflet) of the lysosomal membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +synonym: "external leaflet of lysosomal membrane" EXACT [GOC:dos] +synonym: "external side of lysosomal membrane" EXACT [] +is_a: GO:0098562 ! cytoplasmic side of membrane +relationship: part_of GO:0005765 ! lysosomal membrane + +[Term] +id: GO:0098575 +name: lumenal side of lysosomal membrane +namespace: cellular_component +def: "The side (leaflet) of the lysosomal membrane that faces the lumen." [GOC:dos] +synonym: "internal leaflet of lysosomal membrane" EXACT [GOC:ab] +synonym: "internal side of lysosomal membrane" EXACT [] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0005765 ! lysosomal membrane + +[Term] +id: GO:0098576 +name: lumenal side of membrane +namespace: cellular_component +def: "Any side (leaflet) of a membrane that faces the lumen of an organelle." [GOC:dos] +is_a: GO:0098552 ! side of membrane +relationship: part_of GO:0031090 ! organelle membrane + +[Term] +id: GO:0098577 +name: inactive sex chromosome +namespace: cellular_component +def: "A sex chromosome that has been inactivated." [GOC:dos] +synonym: "inactivated sex chromosome" EXACT [] +is_a: GO:0000803 ! sex chromosome + +[Term] +id: GO:0098578 +name: condensed chromatin of inactivated sex chromosome +namespace: cellular_component +def: "A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation." [GOC:dos] +is_a: GO:0001739 ! sex chromatin +intersection_of: GO:0005720 ! nuclear heterochromatin +intersection_of: part_of GO:0098577 ! inactive sex chromosome +relationship: part_of GO:0098577 ! inactive sex chromosome + +[Term] +id: GO:0098579 +name: active sex chromosome +namespace: cellular_component +def: "A sex chromosome that has not been inactivated." [GOC:dos] +is_a: GO:0000803 ! sex chromosome + +[Term] +id: GO:0098580 +name: chromatin of active sex chromosome +namespace: cellular_component +def: "Chromatin that is part of an active sex chromosome." [GOC:dos, PMID:23816838] +comment: Some gene products are known to be associated with the chromatin of active sex chromosome, but not that of inactive sex chromosomes or autosome, e.g. see: Froberg et al., 2003 (PMID:23816838). +is_a: GO:0001739 ! sex chromatin +intersection_of: GO:0000790 ! nuclear chromatin +intersection_of: part_of GO:0098579 ! active sex chromosome +relationship: part_of GO:0098579 ! active sex chromosome + +[Term] +id: GO:0098581 +name: detection of external biotic stimulus +namespace: biological_process +def: "The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated." [GOC:dos] +synonym: "detection of exogenous biotic stimulus" EXACT [] +is_a: GO:0009595 ! detection of biotic stimulus +is_a: GO:0043207 ! response to external biotic stimulus +created_by: dos +creation_date: 2014-01-22T14:20:16Z + +[Term] +id: GO:0098582 +name: innate vocalization behavior +namespace: biological_process +def: "A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur." [GOC:BHF, GOC:dos, GOC:rl] +is_a: GO:0071625 ! vocalization behavior +created_by: dos +creation_date: 2014-01-24T12:47:01Z + +[Term] +id: GO:0098583 +name: learned vocalization behavior +namespace: biological_process +def: "A vocalization behavior that is the result of learning." [GOC:BHF, GOC:dos, GOC:rl, PMID:16418265, PMID:17035521] +comment: Examples include human speech and learned bird song. +is_a: GO:0071625 ! vocalization behavior +is_a: GO:0098598 ! learned vocalization behavior or vocal learning +created_by: dos +creation_date: 2014-01-24T12:48:57Z + +[Term] +id: GO:0098584 +name: host cell synaptic vesicle +namespace: cellular_component +def: "A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." [GOC:dos] +is_a: GO:0044161 ! host cell cytoplasmic vesicle +relationship: part_of GO:0044221 ! host cell synapse +created_by: dos +creation_date: 2014-01-24T13:14:13Z + +[Term] +id: GO:0098585 +name: host cell synaptic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a host synaptic vesicle." [GOC:dos] +is_a: GO:0044162 ! host cell cytoplasmic vesicle membrane +relationship: part_of GO:0098584 ! host cell synaptic vesicle +created_by: dos +creation_date: 2014-01-24T13:15:14Z + +[Term] +id: GO:0098586 +name: cellular response to virus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus." [GOC:dos] +is_a: GO:0009615 ! response to virus +created_by: dos +creation_date: 2014-01-24T14:54:08Z + +[Term] +id: GO:0098588 +name: bounding membrane of organelle +namespace: cellular_component +def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos] +comment: Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. +is_a: GO:0031090 ! organelle membrane +created_by: dos +creation_date: 2014-02-26T13:41:31Z + +[Term] +id: GO:0098589 +name: membrane region +namespace: cellular_component +def: "A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane." [GOC:dos] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. +subset: gocheck_do_not_manually_annotate +synonym: "region of membrane" EXACT [] +is_a: GO:0016020 ! membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0098805 ! whole membrane +disjoint_from: GO:0098805 ! whole membrane +relationship: part_of GO:0098805 ! whole membrane +creation_date: 2014-03-06T11:37:54Z + +[Term] +id: GO:0098590 +name: plasma membrane region +namespace: cellular_component +def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. +subset: gocheck_do_not_manually_annotate +synonym: "region of plasma membrane" EXACT [] +is_a: GO:0016020 ! membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005886 ! plasma membrane +created_by: dos +creation_date: 2014-03-06T11:55:32Z + +[Term] +id: GO:0098591 +name: external side of apical plasma membrane +namespace: cellular_component +def: "The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface." [GOC:ab, GOC:dos] +is_a: GO:0009897 ! external side of plasma membrane +relationship: part_of GO:0016324 ! apical plasma membrane +created_by: dos +creation_date: 2014-03-06T12:04:33Z + +[Term] +id: GO:0098592 +name: cytoplasmic side of apical plasma membrane +namespace: cellular_component +def: "The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm." [GOC:ab, GOC:dos] +is_a: GO:0009898 ! cytoplasmic side of plasma membrane +relationship: part_of GO:0016324 ! apical plasma membrane +created_by: dos +creation_date: 2014-03-06T12:07:32Z + +[Term] +id: GO:0098593 +name: goblet cell theca +namespace: cellular_component +def: "A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel." [PMID:6541604] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005856 ! cytoskeleton +created_by: dos +creation_date: 2014-03-11T14:52:33Z + +[Term] +id: GO:0098594 +name: mucin granule +namespace: cellular_component +def: "A secretory granule that contains mucin." [PMID:16377632] +is_a: GO:0030141 ! secretory granule +created_by: dos +creation_date: 2014-03-11T15:59:11Z + +[Term] +id: GO:0098595 +name: perivitelline space +namespace: cellular_component +def: "The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane)." [GOC:dos] +is_a: GO:0005576 ! extracellular region +created_by: dos +creation_date: 2014-04-08T16:07:31Z + +[Term] +id: GO:0098596 +name: imitative learning +namespace: biological_process +def: "Learning in which new behaviors are acquired through imitation." [GOC:dos, Wikipedia:Imitative_learning&oldid=593192364] +xref: Wikipedia:Imitative_learning +xref: Wikipedia:Observational_learning#Observational_learning_compared_to_imitation +is_a: GO:0098597 ! observational learning +created_by: dos +creation_date: 2014-04-10T11:00:39Z + +[Term] +id: GO:0098597 +name: observational learning +namespace: biological_process +def: "Learning that occurs through observing the behavior of others." [GOC:dos, Wikipedia:Observational_learning&oldid=603524137] +comment: Observation here is used in a broad sense to include perception of the behavior of others via any form or combination of forms of sensory perception (visual, auditory etc). Observational learning is broader than imitative learning in that it does not require a duplication of the behavior exhibited by the model. +xref: Wikipedia:Observational_learning +is_a: GO:0007612 ! learning +created_by: dos +creation_date: 2014-04-10T11:07:10Z + +[Term] +id: GO:0098598 +name: learned vocalization behavior or vocal learning +namespace: biological_process +def: "Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned." [GOC:BHF, GOC:dos, GOC:rl, PMID:16418265, PMID:17035521] +comment: This grouping term is necessary because, in the absence of conditional mutations, it is not possible to use phenotypic evidence to distinguish an effect on vocal learning from an effect on learned vocalisation behavior. +is_a: GO:0007611 ! learning or memory +created_by: dos +creation_date: 2014-04-10T11:34:33Z + +[Term] +id: GO:0098599 +name: palmitoyl hydrolase activity +namespace: molecular_function +def: "Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate." [GOC:dos, GOC:pg] +xref: Reactome:R-HSA-5690046 "PPT2 hydrolyses PALMCoA to PALM" +xref: Reactome:R-HSA-9027670 "ESTG binding induces ESR depalmitoylation" +is_a: GO:0016787 ! hydrolase activity +relationship: part_of GO:0098734 ! macromolecule depalmitoylation +created_by: dos +creation_date: 2014-04-11T17:57:36Z + +[Term] +id: GO:0098600 +name: selenomethionine gamma-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid." [PMID:11578145, PMID:16037612, PMID:16444005] +xref: Reactome:R-HSA-2408537 "Excess SeMet is cleaved into MeSeH by CTH" +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: dos +creation_date: 2014-04-15T15:00:28Z + +[Term] +id: GO:0098601 +name: selenomethionine adenosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine." [PMID:2339986] +xref: Reactome:R-HSA-2408551 "SeMet is converted to AdoSeMet by MAT" +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +created_by: dos +creation_date: 2014-04-15T15:15:03Z + +[Term] +id: GO:0098603 +name: selenol Se-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine." [PMID:1711890] +xref: Reactome:R-HSA-2408544 "AdoSeMet is converted to AdeSeHCys by MetTrans(1)" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0098604 +name: adenosylselenohomocysteinase activity +namespace: molecular_function +def: "Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine." [GOC:dos, PMID:1711890, PMID:7305945] +xref: Reactome:R-HSA-2408532 "AdeSeHCys is hydrolysed to SeHCys by AHCY" +is_a: GO:0016802 ! trialkylsulfonium hydrolase activity +created_by: dos +creation_date: 2014-04-16T10:53:22Z + +[Term] +id: GO:0098605 +name: selenocystathionine beta-synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O." [PMID:6456763] +xref: Reactome:R-HSA-2408559 "SeHCys and Ser are dehydrated into SeCysta by CBS" +is_a: GO:0016836 ! hydro-lyase activity +created_by: dos +creation_date: 2014-04-16T11:07:50Z + +[Term] +id: GO:0098606 +name: selenocystathionine gamma-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid." [PMID:6456763] +xref: Reactome:R-HSA-2408543 "SeCysta is hydrolysed to Sec by CTH" +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: dos +creation_date: 2014-04-16T11:20:00Z + +[Term] +id: GO:0098607 +name: methylselenocysteine deselenhydrase activity +namespace: molecular_function +def: "Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol." [PMID:17451884, PMID:20383543] +xref: Reactome:R-HSA-2408539 "MeSec is hydrolysed to MeSeH by CTH" +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: dos +creation_date: 2014-04-16T11:24:12Z + +[Term] +id: GO:0098608 +name: methylselenol demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH." [PMID:17451884, PMID:17988700] +xref: Reactome:R-HSA-2408530 "MeSeH is hydrolysed to H2Se by methylselenol demethylase" +is_a: GO:0032451 ! demethylase activity +created_by: dos +creation_date: 2014-04-16T11:28:00Z + +[Term] +id: GO:0098609 +name: cell-cell adhesion +namespace: biological_process +alt_id: GO:0016337 +def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos] +synonym: "single organismal cell-cell adhesion" RELATED [] +is_a: GO:0007155 ! cell adhesion +created_by: dos +creation_date: 2014-04-16T13:40:03Z + +[Term] +id: GO:0098610 +name: adhesion between unicellular organisms +namespace: biological_process +alt_id: GO:0098741 +def: "The attachment of two unicellular organisms to each other." [GOC:dos] +synonym: "adhesion between unicellular organisms via cell-wall interaction" NARROW [] +synonym: "multi-organismal cell-cell adhesion" BROAD [] +is_a: GO:0098609 ! cell-cell adhesion +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon:33208 +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18814 xsd:anyURI + +[Term] +id: GO:0098613 +name: methaneselenol methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide." [PMID:14705, PMID:17988700, PMID:4380351] +xref: Reactome:R-HSA-2408541 "MeSeH is methylated to Me2Se by MeSeH methyltransferase" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0098614 +name: hydrogen selenide methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol." [PMID:14705, PMID:17988700] +xref: Reactome:R-HSA-2408536 "H2Se is methylated to MeSeH by H2Se methyltransferase" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0098615 +name: dimethyl selenide methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium." [PMID:17988700, PMID:3350800] +xref: Reactome:R-HSA-2408554 "Me2Se is methylated to Me3Se+ by INMT" +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0098616 +name: selenate adenylyltransferase (ATP) activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate." [PMID:2537056] +xref: Reactome:R-HSA-2408525 "H2SeO4 is converted to APSe by PAPSS1,2" +is_a: GO:0070566 ! adenylyltransferase activity + +[Term] +id: GO:0098617 +name: adenylylselenate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate." [PMID:2537056] +xref: Reactome:R-HSA-2408540 "APSe is phosphorylated to PAPSe by PAPSS1,2" +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0098618 +name: selenomethionine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met)." [PMID:16661668, PMID:16661782] +xref: Reactome:R-HSA-2408546 "tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex" +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0098619 +name: selenocysteine-tRNA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate." [PMID:8890909, PMID:9431993, PMID:9637248] +xref: Reactome:R-HSA-2408526 "tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer" +is_a: GO:0004812 ! aminoacyl-tRNA ligase activity + +[Term] +id: GO:0098620 +name: seryl-selenocysteinyl-tRNA kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP." [PMID:15317934] +xref: Reactome:R-HSA-2408507 "Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK" +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0098621 +name: phosphoseryl-selenocysteinyl-tRNA selenium transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid." [PMID:17142313, PMID:19608919] +xref: Reactome:R-HSA-2408555 "Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by SEPSECS tetramer" +is_a: GO:0016785 ! transferase activity, transferring selenium-containing groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0098622 +name: selenodiglutathione-disulfide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+." [PMID:1569062] +xref: Reactome:R-HSA-2408542 "GSSeSG is reduced to GSSeH and GSH by GSR" +is_a: GO:0015036 ! disulfide oxidoreductase activity +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0098623 +name: selenite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O." [PMID:1321713] +xref: Reactome:R-HSA-2408558 "SeO3(2-) is reduced to H2Se by TXNRD1" +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0098624 +name: 3'-Phosphoadenylylselenate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+." [PMID:14723223] +synonym: "PAPSe reductase activity" EXACT [PMID:14723223] +xref: Reactome:R-HSA-2408548 "PAPSe is reduced to SeO3(2-) by PAPSe reductase" +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0098625 +name: methylselenol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O." [PMID:11782468] +xref: Reactome:R-HSA-5263614 "MeSeOH is reduced to MeSeH by TXNRD1" +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0098626 +name: methylseleninic acid reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O." [PMID:11782468] +xref: Reactome:R-HSA-5263616 "MeSeO2H is reduced to MeSeOH by TXNRD1" +is_a: GO:0016651 ! oxidoreductase activity, acting on NAD(P)H + +[Term] +id: GO:0098627 +name: protein arginine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate." [PMID:23770242] +comment: Made part of peptidyl-N-phospho-arginine phosphatase activity on the assumption that arginine phosphorylation in proteins occurs via an N link. +is_a: GO:0004721 ! phosphoprotein phosphatase activity +relationship: part_of GO:0098628 ! peptidyl-N-phospho-arginine dephosphorylation +created_by: dos +creation_date: 2014-04-17T17:57:39Z + +[Term] +id: GO:0098628 +name: peptidyl-N-phospho-arginine dephosphorylation +namespace: biological_process +def: "The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine." [PMID:23770242] +is_a: GO:0006470 ! protein dephosphorylation +created_by: dos +creation_date: 2014-04-17T18:03:31Z + +[Term] +id: GO:0098629 +name: trans-Golgi network membrane organization +namespace: biological_process +def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane." [GOC:di, GOC:dos, PMID:23345439] +is_a: GO:0061024 ! membrane organization + +[Term] +id: GO:0098630 +name: aggregation of unicellular organisms +namespace: biological_process +def: "The clustering together of unicellular organisms in suspension form aggregates." [GOC:dos] +synonym: "aggregation of single cell organisms" EXACT [] +is_a: GO:0098743 ! cell aggregation + +[Term] +id: GO:0098631 +name: cell adhesion mediator activity +namespace: molecular_function +def: "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell." [Wikipedia:Cell_adhesion] +synonym: "cell adhesion molecule" EXACT [] +synonym: "protein binding involved in cell adhesion" EXACT [] +is_a: GO:0005488 ! binding +intersection_of: GO:0005488 ! binding +intersection_of: part_of GO:0007155 ! cell adhesion +relationship: part_of GO:0007155 ! cell adhesion + +[Term] +id: GO:0098632 +name: cell-cell adhesion mediator activity +namespace: molecular_function +def: "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell." [Wikipedia:Cell_adhesion] +synonym: "cell-cell adhesion molecule" EXACT [] +synonym: "protein binding involved in cell-cell adhesion" EXACT [] +is_a: GO:0005515 ! protein binding +is_a: GO:0098631 ! cell adhesion mediator activity +intersection_of: GO:0005515 ! protein binding +intersection_of: part_of GO:0098609 ! cell-cell adhesion +relationship: part_of GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0098633 +name: collagen fibril binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a collagen fibril." [GOC:dos, PMID:21421911] +is_a: GO:0044877 ! protein-containing complex binding + +[Term] +id: GO:0098634 +name: cell-matrix adhesion mediator activity +namespace: molecular_function +def: "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix." [Wikipedia:Cell_adhesion] +synonym: "cell-matrix adhesion molecule" EXACT [] +synonym: "protein binding involved in cell-matrix adhesion" EXACT [] +is_a: GO:0098631 ! cell adhesion mediator activity +intersection_of: GO:0005488 ! binding +intersection_of: part_of GO:0007160 ! cell-matrix adhesion +relationship: part_of GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0098635 +name: protein complex involved in cell-cell adhesion +namespace: cellular_component +def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos] +is_a: GO:0098636 ! protein complex involved in cell adhesion + +[Term] +id: GO:0098636 +name: protein complex involved in cell adhesion +namespace: cellular_component +alt_id: GO:1990307 +def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos] +synonym: "cell adhesion complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0098637 +name: protein complex involved in cell-matrix adhesion +namespace: cellular_component +def: "Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion." [GOC:dos] +is_a: GO:0098636 ! protein complex involved in cell adhesion + +[Term] +id: GO:0098638 +name: laminin binding involved in cell-matrix adhesion +namespace: molecular_function +def: "Any laminin protein binding that occurs as part of cell-matrix adhesion." [GOC:dos] +is_a: GO:0043236 ! laminin binding +is_a: GO:0098634 ! cell-matrix adhesion mediator activity +intersection_of: GO:0043236 ! laminin binding +intersection_of: part_of GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0098639 +name: collagen binding involved in cell-matrix adhesion +namespace: molecular_function +def: "Any collagen binding that occurs as part of cell-matrix adhesion." [GOC:dos] +is_a: GO:0005518 ! collagen binding +is_a: GO:0098634 ! cell-matrix adhesion mediator activity +intersection_of: GO:0005518 ! collagen binding +intersection_of: part_of GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0098640 +name: integrin binding involved in cell-matrix adhesion +namespace: molecular_function +def: "Any integrin binding that occurs as part of the process of cell-matrix adhesion." [GOC:dos] +is_a: GO:0005178 ! integrin binding +is_a: GO:0098634 ! cell-matrix adhesion mediator activity +intersection_of: GO:0005178 ! integrin binding +intersection_of: part_of GO:0007160 ! cell-matrix adhesion + +[Term] +id: GO:0098641 +name: cadherin binding involved in cell-cell adhesion +namespace: molecular_function +def: "Any cadherin binding that occurs as part of the process of cell-cell adhesion." [GOC:dos] +is_a: GO:0045296 ! cadherin binding +is_a: GO:0098632 ! cell-cell adhesion mediator activity +intersection_of: GO:0045296 ! cadherin binding +intersection_of: part_of GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0098642 +name: network-forming collagen trimer +namespace: cellular_component +def: "A collagen trimer that forms networks." [PMID:21421911] +is_a: GO:0005581 ! collagen trimer +intersection_of: GO:0005581 ! collagen trimer +intersection_of: part_of GO:0098645 ! collagen network +relationship: part_of GO:0098645 ! collagen network + +[Term] +id: GO:0098643 +name: banded collagen fibril +namespace: cellular_component +def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:21421911] +is_a: GO:0098644 ! complex of collagen trimers +is_a: GO:0099512 ! supramolecular fiber + +[Term] +id: GO:0098644 +name: complex of collagen trimers +namespace: cellular_component +def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos] +synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541] +synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911] +is_a: GO:0099080 ! supramolecular complex +relationship: has_part GO:0005581 ! collagen trimer +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0098645 +name: collagen network +namespace: cellular_component +def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] +is_a: GO:0098644 ! complex of collagen trimers +is_a: GO:0099081 ! supramolecular polymer + +[Term] +id: GO:0098646 +name: collagen sheet +namespace: cellular_component +def: "A protein complex that consists of collagen triple helices associated to form a sheet-like network." [GOC:dos, PMID:21421911] +synonym: "collagen hexagonal network" EXACT [PMID:21421911] +is_a: GO:0098645 ! collagen network + +[Term] +id: GO:0098647 +name: collagen beaded filament +namespace: cellular_component +def: "A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure." [GOC:dos, PMID:19693541] +synonym: "beads on a string" RELATED [PMID:19693541] +is_a: GO:0099512 ! supramolecular fiber + +[Term] +id: GO:0098648 +name: collagen anchoring fibril +namespace: cellular_component +def: "A specialised collagen fibril that functions as an anchor, binding to other collagen structures." [GOC:dos] +is_a: GO:0098644 ! complex of collagen trimers + +[Term] +id: GO:0098649 +name: response to peptidyl-dipeptidase A inhibitor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus." [GOC:dos] +synonym: "response to ACE inhibitor" NARROW [] +synonym: "response to angiotensin-converting enzyme inhibitor" NARROW [] +is_a: GO:0042493 ! response to drug + +[Term] +id: GO:0098650 +name: peptidyl-proline 4-dioxygenase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a peptidyl-proline 4-dioxygenase." [GOC:dos, GOC:kvm] +is_a: GO:0019899 ! enzyme binding + +[Term] +id: GO:0098651 +name: basement membrane collagen trimer +namespace: cellular_component +def: "Any collagen timer that is part of a basement membrane." [GOC:dos, PMID:21421911] +is_a: GO:0005581 ! collagen trimer +intersection_of: GO:0005581 ! collagen trimer +intersection_of: part_of GO:0005604 ! basement membrane +relationship: part_of GO:0005604 ! basement membrane + +[Term] +id: GO:0098652 +name: collagen type VII anchoring fibril +namespace: cellular_component +def: "An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis." [PMID:19693541] +is_a: GO:0098648 ! collagen anchoring fibril + +[Term] +id: GO:0098653 +name: centromere clustering +namespace: biological_process +alt_id: GO:0098587 +def: "The process by which centromeres/kinetochores become localized to clusters." [GOC:di, GOC:dos, PMID:10761928, PMID:23283988, PMID:8486732] +comment: As inner kinetochores are an integral part of centromeres, we treat centromere and kinetochore clustering as the same process. +synonym: "kinetochore clustering" EXACT [] +is_a: GO:0050000 ! chromosome localization +is_a: GO:0072765 ! centromere localization +created_by: dos +creation_date: 2014-05-23T19:03:37Z + +[Term] +id: GO:0098654 +name: CENP-A recruiting complex +namespace: cellular_component +def: "A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere." [PMID:24774534] +synonym: "MIS18 complex" NARROW [GOC:bhm, GOC:vw] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0098655 +name: cation transmembrane transport +namespace: biological_process +alt_id: GO:0099132 +def: "The process in which a cation is transported across a membrane." [GOC:dos, GOC:vw] +synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW [] +is_a: GO:0006812 ! cation transport +is_a: GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0098656 +name: anion transmembrane transport +namespace: biological_process +alt_id: GO:0099133 +def: "The process in which an anion is transported across a membrane." [GOC:dos, GOC:vw] +synonym: "ATP hydrolysis coupled anion transmembrane transport" NARROW [] +is_a: GO:0006820 ! anion transport +is_a: GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0098657 +name: import into cell +namespace: biological_process +def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos] +synonym: "uptake" BROAD [] +is_a: GO:0006810 ! transport + +[Term] +id: GO:0098658 +name: inorganic anion import across plasma membrane +namespace: biological_process +def: "The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "inorganic anion import into cell" EXACT [] +is_a: GO:0098661 ! inorganic anion transmembrane transport +is_a: GO:0099587 ! inorganic ion import across plasma membrane + +[Term] +id: GO:0098659 +name: inorganic cation import across plasma membrane +namespace: biological_process +def: "The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "inorganic cation import into cell" EXACT [] +is_a: GO:0098662 ! inorganic cation transmembrane transport +is_a: GO:0099587 ! inorganic ion import across plasma membrane + +[Term] +id: GO:0098660 +name: inorganic ion transmembrane transport +namespace: biological_process +def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "inorganic ion membrane transport" EXACT [] +synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0034220 ! ion transmembrane transport + +[Term] +id: GO:0098661 +name: inorganic anion transmembrane transport +namespace: biological_process +def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "inorganic anion membrane transport" EXACT [] +synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0015698 ! inorganic anion transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:0098660 ! inorganic ion transmembrane transport + +[Term] +id: GO:0098662 +name: inorganic cation transmembrane transport +namespace: biological_process +def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "inorganic cation membrane transport" EXACT [] +synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb] +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:0098660 ! inorganic ion transmembrane transport + +[Term] +id: GO:0098663 +name: obsolete transmembrane transporter activity involved in import into cell +namespace: molecular_function +def: "OBSOLETE. Any transmembrane transporter activity that is involved in importing some substance into a cell." [GOC:dos] +comment: The reason for obsoletion is that this terms partly represents the process "import into cell". +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14322 xsd:anyURI +is_obsolete: true + +[Term] +id: GO:0098664 +name: G protein-coupled serotonin receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands." [GOC:mah] +synonym: "G-protein coupled serotonin receptor signaling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +is_a: GO:0007210 ! serotonin receptor signaling pathway +created_by: dos +creation_date: 2016-12-21T12:07:58Z + +[Term] +id: GO:0098665 +name: serotonin receptor complex +namespace: cellular_component +def: "A protein complex that is capable of serotonin receptor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16116092] +synonym: "5-HT receptor complex" EXACT [] +synonym: "5-hydroxytryptamine receptor complex" EXACT [] +synonym: "5HT receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +created_by: dos +creation_date: 2016-12-21T12:24:56Z + +[Term] +id: GO:0098666 +name: G protein-coupled serotonin receptor complex +namespace: cellular_component +def: "A protein complex that is capable of G protein-coupled serotonin receptor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie] +synonym: "G-protein coupled serotonin receptor complex" EXACT [] +is_a: GO:0098665 ! serotonin receptor complex +is_a: GO:0098878 ! neurotransmitter receptor complex +created_by: dos +creation_date: 2016-12-21T12:28:12Z + +[Term] +id: GO:0098669 +name: superinfection exclusion +namespace: biological_process +def: "The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented." [PMID:11985726, PMID:23692331, PMID:24089557, PMID:8012757, VZ:3971] +xref: VZ:3971 +is_a: GO:0016032 ! viral process +created_by: dos +creation_date: 2017-01-16T17:25:21Z + +[Term] +id: GO:0098670 +name: entry receptor-mediated virion attachment to host cell +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration." [PMID:18351291, VZ:3942] +synonym: "viral attachment to host entry receptor" EXACT [VZ:3942] +xref: VZ:3942 +is_a: GO:0046813 ! receptor-mediated virion attachment to host cell +created_by: dos +creation_date: 2017-01-16T13:18:27Z + +[Term] +id: GO:0098671 +name: adhesion receptor-mediated virion attachment to host cell +namespace: biological_process +def: "The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located." [PMID:18351291, VZ:3943] +synonym: "viral attachment to host adhesion receptor" EXACT [VZ:3943] +xref: VZ:3943 +is_a: GO:0046813 ! receptor-mediated virion attachment to host cell +created_by: dos +creation_date: 2017-01-16T13:22:54Z + +[Term] +id: GO:0098672 +name: evasion by virus of CRISPR-cas system +namespace: biological_process +def: "Any process, either active or passive, by which a virus evades the CRISPR-cas system of its host. Some viruses can directly suppress the CRISPR system." [PMID:23242138, PMID:23446421, PMID:26416740, VZ:3962] +synonym: "CRISPR-cas system evasion by virus" EXACT [VZ:3962] +xref: VZ:3962 +is_a: GO:0019049 ! mitigation of host defenses by virus +created_by: dos +creation_date: 2017-01-16T13:38:27Z + +[Term] +id: GO:0098673 +name: inhibition of host DNA replication by virus +namespace: biological_process +def: "Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication." [PMID:17010157, PMID:21205014] +is_a: GO:0019054 ! modulation by virus of host cellular process +created_by: dos +creation_date: 2017-01-17T15:58:15Z + +[Term] +id: GO:0098674 +name: extrinsic component of neuronal dense core vesicle membrane +namespace: cellular_component +def: "The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098922 ! extrinsic component of dense core granule membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0099012 ! neuronal dense core vesicle membrane +relationship: part_of GO:0099012 ! neuronal dense core vesicle membrane +created_by: dos +creation_date: 2017-01-17T16:20:56Z + +[Term] +id: GO:0098675 +name: intrinsic component of neuronal dense core vesicle membrane +namespace: cellular_component +def: "The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to neuronal dense core granule membrane" EXACT [] +is_a: GO:0098956 ! intrinsic component of dense core granule membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0099012 ! neuronal dense core vesicle membrane +relationship: part_of GO:0099012 ! neuronal dense core vesicle membrane +created_by: dos +creation_date: 2017-01-17T16:22:44Z + +[Term] +id: GO:0098676 +name: modulation of host virulence by virus +namespace: biological_process +def: "Any process by which a virus modulates the ability of its host to infect and/or damage an organism for which it is a host. Typically this involves a phage modulating the virulence of a bacterium. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production exotoxins or provide protection against host immune defenses." [PMID:10913072, PMID:11553559, PMID:23981100, VZ:3965] +xref: VZ:3965 +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0050789 ! regulation of biological process +relationship: regulates GO:0009405 ! pathogenesis +created_by: dos +creation_date: 2017-01-19T11:59:46Z + +[Term] +id: GO:0098677 +name: virion maturation +namespace: biological_process +def: "Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection." [ISBN:0781718325, UniProtKB-KW:KW-0917, VZ:1946] +synonym: "viral particle maturation" EXACT [] +synonym: "virus particle maturation" RELATED [] +xref: UniProtKB-KW:KW-0917 +xref: VZ:1946 +is_a: GO:0016032 ! viral process +relationship: part_of GO:0019075 ! virus maturation +created_by: dos +creation_date: 2017-01-19T12:49:22Z + +[Term] +id: GO:0098678 +name: viral tropism switching +namespace: biological_process +def: "A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase." [PMID:6232613, VZ:4498] +xref: VZ:4498 +is_a: GO:0016032 ! viral process +created_by: dos +creation_date: 2017-01-19T13:05:51Z + +[Term] +id: GO:0098679 +name: obsolete regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate catabloism." [PMID:16408318] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of carbohydrate catabolism by regulation of transcription from RNA polymerase II promoter" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2017-01-31T14:46:21Z + +[Term] +id: GO:0098680 +name: template-free RNA nucleotidyltransferase +namespace: molecular_function +def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template." [GOC:BHF, GOC:BHF_telomere, GOC:dos, GOC:nc, PMID:15994230] +is_a: GO:0016779 ! nucleotidyltransferase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: dos +creation_date: 2017-01-31T15:51:56Z + +[Term] +id: GO:0098681 +name: synaptic ribbon +namespace: cellular_component +def: "A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical." [PMID:15626493] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +created_by: dos +creation_date: 2017-02-05T15:59:43Z + +[Term] +id: GO:0098682 +name: arciform density +namespace: cellular_component +def: "An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane." [PMID:15626493] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0097470 ! ribbon synapse +created_by: dos +creation_date: 2017-02-05T16:12:22Z + +[Term] +id: GO:0098683 +name: cochlear hair cell ribbon synapse +namespace: cellular_component +def: "A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density." [PMID:15626493] +subset: goslim_synapse +is_a: GO:0097470 ! ribbon synapse +created_by: dos +creation_date: 2017-02-05T16:16:49Z + +[Term] +id: GO:0098684 +name: photoreceptor ribbon synapse +namespace: cellular_component +def: "A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon." [PMID:15626493] +subset: goslim_synapse +is_a: GO:0097470 ! ribbon synapse +created_by: dos +creation_date: 2017-02-05T16:26:27Z + +[Term] +id: GO:0098685 +name: Schaffer collateral - CA1 synapse +namespace: cellular_component +def: "A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell." [PMID:16399689] +subset: goslim_synapse +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-02-05T16:29:43Z + +[Term] +id: GO:0098686 +name: hippocampal mossy fiber to CA3 synapse +namespace: cellular_component +def: "One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell." [DOI:10.1002/1096-9861, PMID:13869693, PMID:23264762] +subset: goslim_synapse +is_a: GO:0098984 ! neuron to neuron synapse +intersection_of: GO:0045202 ! synapse +intersection_of: has_part GO:0097464 ! thorny excrescence +intersection_of: has_part GO:1990026 ! hippocampal mossy fiber expansion +relationship: has_part GO:0097464 ! thorny excrescence +relationship: has_part GO:1990026 ! hippocampal mossy fiber expansion +created_by: dos +creation_date: 2017-02-05T16:29:58Z + +[Term] +id: GO:0098687 +name: chromosomal region +namespace: cellular_component +def: "Any subdivision of a chromosome along its length." [GOC:dos] +comment: Chromosomal regions include parts that are not part of the chromatin. Examples include the kinetochore. +synonym: "chromosome region" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005694 ! chromosome + +[Term] +id: GO:0098688 +name: parallel fiber to Purkinje cell synapse +namespace: cellular_component +def: "An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells." [PMID:16623829, PMID:3209740] +subset: goslim_synapse +is_a: GO:0060076 ! excitatory synapse +created_by: dos +creation_date: 2017-02-21T18:32:05Z + +[Term] +id: GO:0098689 +name: latency-replication decision +namespace: biological_process +def: "The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli." [PMID:19416825, PMID:24339346, VZ:3964] +synonym: "Latency-replication switch" EXACT [] +synonym: "lytic switch" EXACT [] +synonym: "prophage induction" NARROW [] +synonym: "proviral induction" EXACT [] +synonym: "proviral switch" EXACT [] +synonym: "reactivation of latent virus" EXACT [] +xref: VZ:3964 +is_a: GO:0016032 ! viral process +is_a: GO:0050792 ! regulation of viral process +relationship: regulates GO:0019046 ! release from viral latency +created_by: dos +creation_date: 2017-02-28T11:24:26Z + +[Term] +id: GO:0098690 +name: glycinergic synapse +namespace: cellular_component +def: "A synapse that uses glycine as a neurotransmitter." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-03-07T14:50:33Z + +[Term] +id: GO:0098691 +name: dopaminergic synapse +namespace: cellular_component +def: "A synapse that uses dopamine as a neurotransmitter." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-03-07T14:51:52Z + +[Term] +id: GO:0098692 +name: noradrenergic synapse +namespace: cellular_component +def: "A synapse that uses noradrenaline as a neurotransmitter." [GOC:dos] +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-03-07T14:57:24Z + +[Term] +id: GO:0098693 +name: regulation of synaptic vesicle cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle." [GOC:dos] +subset: goslim_synapse +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099504 ! synaptic vesicle cycle +relationship: regulates GO:0099504 ! synaptic vesicle cycle +created_by: dos +creation_date: 2017-03-21T16:06:48Z + +[Term] +id: GO:0098694 +name: regulation of synaptic vesicle budding from presynaptic endocytic zone membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:1900242 ! regulation of synaptic vesicle endocytosis +is_a: GO:1902803 ! regulation of synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016185 ! synaptic vesicle budding from presynaptic endocytic zone membrane +relationship: regulates GO:0016185 ! synaptic vesicle budding from presynaptic endocytic zone membrane +created_by: dos +creation_date: 2017-04-04T17:03:29Z + +[Term] +id: GO:0098695 +name: inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels +namespace: molecular_function +def: "Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GOC:dos] +subset: goslim_synapse +synonym: "IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT [] +is_a: GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +intersection_of: GO:0005220 ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2017-04-04T17:07:09Z + +[Term] +id: GO:0098696 +name: regulation of neurotransmitter receptor localization to postsynaptic specialization membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:1902683 ! regulation of receptor localization to synapse +is_a: GO:1904375 ! regulation of protein localization to cell periphery +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane +relationship: regulates GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane +created_by: dos +creation_date: 2017-04-04T16:33:38Z + +[Term] +id: GO:0098697 +name: ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels +namespace: molecular_function +def: "Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005219 ! ryanodine-sensitive calcium-release channel activity +intersection_of: GO:0005219 ! ryanodine-sensitive calcium-release channel activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2017-04-04T17:11:38Z + +[Term] +id: GO:0098698 +name: postsynaptic specialization assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0070925 ! organelle assembly +is_a: GO:0099084 ! postsynaptic specialization organization +relationship: part_of GO:0099068 ! postsynapse assembly +created_by: dos +creation_date: 2017-04-04T17:22:01Z + +[Term] +id: GO:0098699 +name: structural constituent of presynaptic actin cytoskeleton +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005200 ! structural constituent of cytoskeleton +is_a: GO:0099181 ! structural constituent of presynapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0099143 ! presynaptic actin cytoskeleton +intersection_of: part_of GO:0099140 ! presynaptic actin cytoskeleton organization +relationship: occurs_in GO:0099143 ! presynaptic actin cytoskeleton +relationship: part_of GO:0099140 ! presynaptic actin cytoskeleton organization +created_by: dos +creation_date: 2017-06-09T18:33:07Z + +[Term] +id: GO:0098700 +name: neurotransmitter loading into synaptic vesicle +namespace: biological_process +def: "The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps." [GOC:bf, GOC:pad, GOC:PARL, PMID:10099709, PMID:15217342] +subset: goslim_synapse +synonym: "neurotransmitter import into synaptic vesicle" EXACT [] +synonym: "neurotransmitter uptake into synaptic vesicle" EXACT [PMID:15217342] +synonym: "synaptic vesicle neurotransmitter loading" EXACT syngo_official_label [] +is_a: GO:0006836 ! neurotransmitter transport +is_a: GO:0051649 ! establishment of localization in cell +relationship: part_of GO:0099504 ! synaptic vesicle cycle + +[Term] +id: GO:0098702 +name: adenine import across plasma membrane +namespace: biological_process +alt_id: GO:0061488 +def: "The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "adenine import into cell" EXACT [] +is_a: GO:0015853 ! adenine transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1904823 ! purine nucleobase transmembrane transport +created_by: dph +creation_date: 2012-12-06T14:51:42Z + +[Term] +id: GO:0098703 +name: calcium ion import across plasma membrane +namespace: biological_process +alt_id: GO:1990035 +def: "The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "calcium ion import into cell" EXACT [] +synonym: "calcium ion uptake into cell" EXACT [GOC:vw] +is_a: GO:0097553 ! calcium ion transmembrane import into cytosol +is_a: GO:0098659 ! inorganic cation import across plasma membrane +is_a: GO:1902656 ! calcium ion import into cytosol +created_by: mah +creation_date: 2013-02-07T13:07:59Z + +[Term] +id: GO:0098704 +name: carbohydrate import across plasma membrane +namespace: biological_process +alt_id: GO:0097319 +def: "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "carbohydrate import into cell" EXACT [] +is_a: GO:0034219 ! carbohydrate transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pr +creation_date: 2012-05-31T02:45:02Z + +[Term] +id: GO:0098705 +name: copper ion import across plasma membrane +namespace: biological_process +alt_id: GO:0015678 +alt_id: GO:1902861 +def: "The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "copper cation import into cell" EXACT [] +synonym: "copper ion import into cell" EXACT [] +synonym: "high affinity copper ion transport" NARROW [] +synonym: "high affinity copper transport" NARROW [] +synonym: "high-affinity copper ion transport" NARROW [] +is_a: GO:0015677 ! copper ion import +is_a: GO:0015679 ! plasma membrane copper ion transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: mah +creation_date: 2014-04-03T13:26:04Z + +[Term] +id: GO:0098706 +name: iron ion import across cell outer membrane +namespace: biological_process +alt_id: GO:0015683 +alt_id: GO:0097461 +def: "The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space." [GOC:mah, PMID:23192658] +synonym: "ferric ion import into cell" EXACT [GOC:mah] +synonym: "ferric iron import across cell outer membrane" NARROW [] +synonym: "ferric iron import into cell" EXACT [] +synonym: "ferric iron transmembrane transport" BROAD [] +synonym: "high affinity ferric iron transport" NARROW [] +synonym: "high-affinity ferric iron transmembrane transport" NARROW [] +is_a: GO:0034755 ! iron ion transmembrane transport +created_by: pr +creation_date: 2012-12-20T08:33:03Z + +[Term] +id: GO:0098708 +name: glucose import across plasma membrane +namespace: biological_process +alt_id: GO:0061490 +alt_id: GO:1990821 +def: "The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "glucose import into cell" EXACT [] +synonym: "high affinity glucose import" NARROW [] +is_a: GO:0046323 ! glucose import +is_a: GO:0140271 ! hexose import across plasma membrane +created_by: al +creation_date: 2012-12-06T14:54:07Z + +[Term] +id: GO:0098709 +name: glutathione import across plasma membrane +namespace: biological_process +alt_id: GO:0036347 +def: "The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "glutathione import into cell" EXACT [] +synonym: "glutathione uptake" EXACT [GOC:bf] +is_a: GO:0034775 ! glutathione transmembrane transport +is_a: GO:0140207 ! tripeptide import across plasma membrane +created_by: bf +creation_date: 2012-09-18T14:29:19Z + +[Term] +id: GO:0098710 +name: guanine import across plasma membrane +namespace: biological_process +alt_id: GO:0061489 +def: "The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "guanine import into cell" EXACT [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1903716 ! guanine transmembrane transport +created_by: dph +creation_date: 2012-12-06T14:52:43Z + +[Term] +id: GO:0098711 +name: iron ion import across plasma membrane +namespace: biological_process +alt_id: GO:0097459 +alt_id: GO:0097460 +alt_id: GO:0098707 +def: "The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:mah, PMID:8321236] +synonym: "ferrous ion import into cell" RELATED [GOC:mah] +synonym: "ferrous iron import across plasma membrane" RELATED [] +synonym: "ferrous iron import into cell" RELATED [] +synonym: "iron import into cell" RELATED [GOC:mah] +synonym: "iron ion import into cell" EXACT [] +is_a: GO:0033212 ! iron import into cell +is_a: GO:0034755 ! iron ion transmembrane transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: pr +creation_date: 2012-12-20T08:29:00Z + +[Term] +id: GO:0098712 +name: L-glutamate import across plasma membrane +namespace: biological_process +alt_id: GO:1903802 +alt_id: GO:1990123 +def: "The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "L-glutamate import into cell" EXACT [] +synonym: "L-glutamate(1-) import across plasma membrane" BROAD [] +synonym: "L-glutamate(1-) import into cell" EXACT [] +is_a: GO:0001504 ! neurotransmitter uptake +is_a: GO:0015813 ! L-glutamate transmembrane transport +is_a: GO:0051938 ! L-glutamate import +is_a: GO:0089718 ! amino acid import across plasma membrane +created_by: mah +creation_date: 2013-06-12T12:32:47Z + +[Term] +id: GO:0098713 +name: leucine import across plasma membrane +namespace: biological_process +alt_id: GO:1990122 +def: "The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "L-leucine import into cell" NARROW [GOC:mah] +synonym: "leucine import into cell" EXACT [] +is_a: GO:0015820 ! leucine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +created_by: mah +creation_date: 2013-06-12T12:27:47Z + +[Term] +id: GO:0098714 +name: malate import across plasma membrane +namespace: biological_process +alt_id: GO:0097405 +def: "The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "malate import into cell" EXACT [] +is_a: GO:0071423 ! malate transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pr +creation_date: 2012-10-29T11:18:48Z + +[Term] +id: GO:0098715 +name: malonic acid import across plasma membrane +namespace: biological_process +alt_id: GO:0097406 +def: "The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "malonate import into cell" EXACT [] +synonym: "malonic acid import into cell" EXACT [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1901553 ! malonic acid transmembrane transport +created_by: pr +creation_date: 2012-10-30T15:33:37Z + +[Term] +id: GO:0098716 +name: nickel cation import across plasma membrane +namespace: biological_process +alt_id: GO:0090509 +def: "The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "nickel cation import into cell" EXACT [] +is_a: GO:0035444 ! nickel cation transmembrane transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: tb +creation_date: 2012-11-16T16:12:53Z + +[Term] +id: GO:0098717 +name: pantothenate import across plasma membrane +namespace: biological_process +alt_id: GO:0044755 +alt_id: GO:1901688 +def: "The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "pantothenate import" RELATED [] +synonym: "pantothenate import into cell" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0042886 ! amide transport +is_a: GO:0051181 ! cofactor transport +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: jl +creation_date: 2012-12-06T13:02:23Z + +[Term] +id: GO:0098718 +name: serine import across plasma membrane +namespace: biological_process +alt_id: GO:0061491 +def: "The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "serine import into cell" EXACT [] +is_a: GO:0032329 ! serine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +created_by: dph +creation_date: 2012-12-06T14:55:29Z + +[Term] +id: GO:0098719 +name: sodium ion import across plasma membrane +namespace: biological_process +alt_id: GO:0097369 +alt_id: GO:1990118 +def: "The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "sodium import" EXACT [] +synonym: "sodium ion import" RELATED [] +synonym: "sodium ion import into cell" EXACT [] +is_a: GO:0035725 ! sodium ion transmembrane transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: pr +creation_date: 2012-08-03T16:55:52Z + +[Term] +id: GO:0098720 +name: succinate import across plasma membrane +namespace: biological_process +alt_id: GO:0097404 +def: "The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "succinate import into cell" EXACT [] +is_a: GO:0071422 ! succinate transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pr +creation_date: 2012-10-29T11:17:44Z + +[Term] +id: GO:0098721 +name: uracil import across plasma membrane +namespace: biological_process +alt_id: GO:1902431 +def: "The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "uracil import into cell" EXACT [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1903791 ! uracil transmembrane transport +created_by: tb +creation_date: 2013-09-27T17:54:23Z + +[Term] +id: GO:0098722 +name: asymmetric stem cell division +namespace: biological_process +def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950] +is_a: GO:0008356 ! asymmetric cell division +is_a: GO:0017145 ! stem cell division + +[Term] +id: GO:0098723 +name: skeletal muscle myofibril +namespace: cellular_component +def: "A myofibril of a skeletal muscle fiber." [GOC:dos] +is_a: GO:0030016 ! myofibril + +[Term] +id: GO:0098724 +name: symmetric stem cell division +namespace: biological_process +def: "Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population." [PMID:19948499, PMID:23303905] +comment: Examples include the self-renewal of spermatogonial stem cells and (some) division during amplification of skeletal muscle satellite cell populations. +is_a: GO:0017145 ! stem cell division +is_a: GO:0098725 ! symmetric cell division + +[Term] +id: GO:0098725 +name: symmetric cell division +namespace: biological_process +def: "Cell division in which both daughter cells are of the same type." [GOC:dos] +is_a: GO:0051301 ! cell division + +[Term] +id: GO:0098726 +name: symmetric division of skeletal muscle satellite stem cell +namespace: biological_process +def: "The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells." [PMID:23303905] +is_a: GO:0048103 ! somatic stem cell division +is_a: GO:0098724 ! symmetric stem cell division + +[Term] +id: GO:0098727 +name: maintenance of cell number +namespace: biological_process +def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos] +is_a: GO:0032502 ! developmental process + +[Term] +id: GO:0098728 +name: germline stem cell asymmetric division +namespace: biological_process +def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos] +is_a: GO:0042078 ! germ-line stem cell division +is_a: GO:0098722 ! asymmetric stem cell division + +[Term] +id: GO:0098729 +name: germline stem cell symmetric division +namespace: biological_process +def: "Division of a germline stem cell to produce two germline stem cells of the same type as the parent." [GOC:dos, PMID:19948499] +is_a: GO:0042078 ! germ-line stem cell division +is_a: GO:0098724 ! symmetric stem cell division + +[Term] +id: GO:0098730 +name: male germline stem cell symmetric division +namespace: biological_process +def: "The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic." [GOC:dos, PMID:19948499] +is_a: GO:0098729 ! germline stem cell symmetric division + +[Term] +id: GO:0098731 +name: skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration +namespace: biological_process +def: "Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells." [PMID:23303905] +is_a: GO:0014834 ! skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration +is_a: GO:0035019 ! somatic stem cell population maintenance + +[Term] +id: GO:0098732 +name: macromolecule deacylation +namespace: biological_process +def: "The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule." [GOC:dos] +is_a: GO:0043412 ! macromolecule modification + +[Term] +id: GO:0098733 +name: hemidesmosome associated protein complex +namespace: cellular_component +def: "Any protein complex that is part of or has some part in a hemidesmosome." [GOC:dos] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0098734 +name: macromolecule depalmitoylation +namespace: biological_process +def: "The removal of palymitoyl groups from a macromolecule." [GOC:dos] +is_a: GO:0098732 ! macromolecule deacylation + +[Term] +id: GO:0098735 +name: positive regulation of the force of heart contraction +namespace: biological_process +def: "Any process that increases the force of heart muscle contraction." [GOC:BHF, GOC:dos, GOC:mtg_cardiac_conduct_nov11, GOC:rl, PMID:17242280] +is_a: GO:0002026 ! regulation of the force of heart contraction + +[Term] +id: GO:0098736 +name: negative regulation of the force of heart contraction +namespace: biological_process +def: "Any process that decreases the force of heart muscle contraction." [GOC:BHF, GOC:dos, GOC:mtg_cardiac_conduct_nov11, GOC:rl, PMID:17242280] +is_a: GO:0002026 ! regulation of the force of heart contraction + +[Term] +id: GO:0098737 +name: protein insertion into plasma membrane +namespace: biological_process +def: "The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers." [GOC:DOS] +is_a: GO:0051205 ! protein insertion into membrane +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0098739 +name: import across plasma membrane +namespace: biological_process +def: "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "uptake" BROAD [] +is_a: GO:0055085 ! transmembrane transport + +[Term] +id: GO:0098740 +name: obsolete multi organism cell adhesion +namespace: biological_process +def: "OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms." [GOC:dos] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true + +[Term] +id: GO:0098742 +name: cell-cell adhesion via plasma-membrane adhesion molecules +namespace: biological_process +def: "The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane." [GOC:dos] +is_a: GO:0098609 ! cell-cell adhesion + +[Term] +id: GO:0098743 +name: cell aggregation +namespace: biological_process +def: "The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation." [GOC:dos] +is_a: GO:0009987 ! cellular process + +[Term] +id: GO:0098744 +name: 1-phosphatidylinositol 4-kinase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of 1-phosphatidylinositol 4-kinase." [PMID:21288895] +is_a: GO:0019209 ! kinase activator activity + +[Term] +id: GO:0098745 +name: Dcp1-Dcp2 complex +namespace: cellular_component +def: "A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA." [GOC:dos, GOC:vw, PMID:22323607] +comment: Additional components may be present, for example in ascomycetes this complex includes an additional regulatory subunit, Edc1. +is_a: GO:0005845 ! mRNA cap binding complex + +[Term] +id: GO:0098746 +name: fast, calcium ion-dependent exocytosis of neurotransmitter +namespace: biological_process +def: "The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release." [GOC:dos, GOC:pad, GOC:PARL, PMID:4405553, PMID:7809151, PMID:7954835] +synonym: "synchronous, calcium ion-dependent exocytosis of neurotransmitter" EXACT [PMID:7954835] +is_a: GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter + +[Term] +id: GO:0098747 +name: slow, calcium ion-dependent exocytosis of neurotransmitter +namespace: biological_process +def: "The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release." [GOC:dos, GOC:pad, GOC:parl, PMID:7809151, PMID:7954835] +is_a: GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter + +[Term] +id: GO:0098749 +name: cerebellar neuron development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] +is_a: GO:0021954 ! central nervous system neuron development +relationship: part_of GO:0021549 ! cerebellum development + +[Term] +id: GO:0098750 +name: FYXD domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a FXYD domain." [GOC:dos, GOC:mr, PMID:10950925, PMID:16403837, PMID:18000745] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0098751 +name: bone cell development +namespace: biological_process +def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] +comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development. +subset: gocheck_do_not_annotate +is_a: GO:0048468 ! cell development +relationship: part_of GO:0060348 ! bone development + +[Term] +id: GO:0098752 +name: integral component of the cytoplasmic side of the plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane." [GOC:dos] +is_a: GO:0005887 ! integral component of plasma membrane +is_a: GO:0031235 ! intrinsic component of the cytoplasmic side of the plasma membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0009898 ! cytoplasmic side of plasma membrane + +[Term] +id: GO:0098753 +name: anchored component of the cytoplasmic side of the plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane." [GOC:dos] +comment: Examples include many myristoylated proteins. +is_a: GO:0031235 ! intrinsic component of the cytoplasmic side of the plasma membrane +is_a: GO:0046658 ! anchored component of plasma membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0009898 ! cytoplasmic side of plasma membrane + +[Term] +id: GO:0098754 +name: detoxification +namespace: biological_process +def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] +subset: goslim_pombe +is_a: GO:0008150 ! biological_process +relationship: part_of GO:0009636 ! response to toxic substance + +[Term] +id: GO:0098755 +name: maintenance of seed dormancy by absisic acid +namespace: biological_process +def: "The process by which seed dormancy is maintained by the presence of absisic acid." [GOC:dos, PMID:9580097] +is_a: GO:0010231 ! maintenance of seed dormancy +intersection_of: GO:0010231 ! maintenance of seed dormancy +intersection_of: part_of GO:0009737 ! response to abscisic acid +relationship: part_of GO:0009737 ! response to abscisic acid + +[Term] +id: GO:0098756 +name: response to interleukin-21 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus." [GOC:BHF, GOC:mah] +synonym: "response to IL-21" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine + +[Term] +id: GO:0098757 +name: cellular response to interleukin-21 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus." [GOC:BHF, GOC:mah] +synonym: "cellular response to IL-21" EXACT [GOC:mah] +is_a: GO:0098756 ! response to interleukin-21 + +[Term] +id: GO:0098758 +name: response to interleukin-8 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus." [GOC:BHF, GOC:mah] +synonym: "response to IL-8" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine + +[Term] +id: GO:0098759 +name: cellular response to interleukin-8 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus." [GOC:BHF, GOC:mah] +synonym: "cellular response to IL-8" EXACT [GOC:mah] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:0098758 ! response to interleukin-8 + +[Term] +id: GO:0098760 +name: response to interleukin-7 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus." [GOC:BHF, GOC:mah] +synonym: "response to IL-7" EXACT [GOC:mah] +is_a: GO:0034097 ! response to cytokine + +[Term] +id: GO:0098761 +name: cellular response to interleukin-7 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus." [GOC:BHF, GOC:mah] +synonym: "cellular response to IL-7" EXACT [GOC:mah] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:0098760 ! response to interleukin-7 + +[Term] +id: GO:0098762 +name: meiotic cell cycle phase +namespace: biological_process +def: "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GOC:dos] +comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0022403 ! cell cycle phase +intersection_of: GO:0022403 ! cell cycle phase +intersection_of: happens_during GO:0051321 ! meiotic cell cycle +relationship: happens_during GO:0051321 ! meiotic cell cycle + +[Term] +id: GO:0098763 +name: mitotic cell cycle phase +namespace: biological_process +def: "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." [GOC:dos] +comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0022403 ! cell cycle phase +intersection_of: GO:0022403 ! cell cycle phase +intersection_of: happens_during GO:0000278 ! mitotic cell cycle +relationship: happens_during GO:0000278 ! mitotic cell cycle + +[Term] +id: GO:0098764 +name: meiosis I cell cycle phase +namespace: biological_process +def: "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs." [GOC:dos] +comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0098762 ! meiotic cell cycle phase + +[Term] +id: GO:0098765 +name: meiosis II cell cycle phase +namespace: biological_process +def: "A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division)." [GOC:dos] +comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0098762 ! meiotic cell cycle phase + +[Term] +id: GO:0098766 +name: obsolete meiosis I M phase +namespace: biological_process +def: "OBSOLETE. M phase during meiosis I." [GOC:dos] +comment: Obsoleted because added in error. +is_obsolete: true +consider: GO:0098762 + +[Term] +id: GO:0098767 +name: obsolete meiosis II M phase +namespace: biological_process +def: "OBSOLETE. M phase during meiosis II." [GOC:dos] +comment: Obsoleted because added in error. +is_obsolete: true +consider: GO:0098762 + +[Term] +id: GO:0098768 +name: meiotic prometaphase I +namespace: biological_process +def: "The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate." [PMID:16012859] +comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). +subset: gocheck_do_not_annotate +is_a: GO:0098764 ! meiosis I cell cycle phase + +[Term] +id: GO:0098769 +name: TIMP family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family." [PMID:22078297] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0098770 +name: FBXO family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction." [PMID:11178263] +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 + +[Term] +id: GO:0098771 +name: inorganic ion homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." [GOC:dos] +is_a: GO:0050801 ! ion homeostasis + +[Term] +id: GO:0098772 +name: molecular function regulator +namespace: molecular_function +def: "A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators." [GOC:dos, GOC:pt] +subset: goslim_flybase_ribbon +is_a: GO:0003674 ! molecular_function +relationship: part_of GO:0065009 ! regulation of molecular function + +[Term] +id: GO:0098773 +name: skin epidermis development +namespace: biological_process +def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos] +is_a: GO:0008544 ! epidermis development +is_a: GO:0060429 ! epithelium development +relationship: part_of GO:0043588 ! skin development + +[Term] +id: GO:0098774 +name: curli +namespace: cellular_component +def: "A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization." [PMID:16704339] +synonym: "tafi" NARROW [PMID:16704339] +synonym: "thin aggregative fimbrae" NARROW [PMID:16704339] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0097311 ! bacterial biofilm matrix + +[Term] +id: GO:0098775 +name: curli assembly +namespace: biological_process +def: "The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex." [PMID:16704339] +is_a: GO:0065003 ! protein-containing complex assembly + +[Term] +id: GO:0098776 +name: protein transport across the cell outer membrane +namespace: biological_process +def: "The directed movement of proteins across the cell outer membrane." [GOC:dos] +is_a: GO:0071806 ! protein transmembrane transport + +[Term] +id: GO:0098777 +name: protein secretion by the type VIII secretion system +namespace: biological_process +def: "Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits." [PMID:19299134, PMID:24080089] +comment: This term is defined so as to leave open the possibility that things other than curli subunits are secreted via same secretory system as that used by curli subunits. +synonym: "T8SS" EXACT [PMID:19299134] +is_a: GO:0098776 ! protein transport across the cell outer membrane + +[Term] +id: GO:0098778 +name: curli subunit secretion coupled to curli assembly +namespace: biological_process +def: "The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface." [PMID:24080089] +synonym: "extracellular nucleation-precipitation pathway" EXACT [PMID:19299134] +is_a: GO:0098777 ! protein secretion by the type VIII secretion system + +[Term] +id: GO:0098779 +name: positive regulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization." [GOC:PARL, PMID:18200046, PMID:23985961] +synonym: "positive regulation of macromitophagy in response to mitochondrial depolarization" EXACT [] +is_a: GO:1901526 ! positive regulation of mitophagy +is_a: GO:1904925 ! positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization +intersection_of: GO:0098780 ! response to mitochondrial depolarisation +intersection_of: positively_regulates GO:0000423 ! mitophagy + +[Term] +id: GO:0098780 +name: response to mitochondrial depolarisation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria." [GOC:dos] +is_a: GO:0033554 ! cellular response to stress + +[Term] +id: GO:0098781 +name: ncRNA transcription +namespace: biological_process +def: "The transcription of non (protein) coding RNA from a DNA template." [GOC:dos] +is_a: GO:0006351 ! transcription, DNA-templated + +[Term] +id: GO:0098782 +name: mechanosensitived potassium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress." [PMID:22282805, PMID:25471887, PMID:25500157] +synonym: "mechanically-gated potassium channel activity" EXACT [] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0140135 ! mechanosensitive cation channel activity + +[Term] +id: GO:0098783 +name: repair of mitotic merotelic kinetochore attachment defect +namespace: biological_process +def: "The cell cycle process that corrects the anomalous association of a single chromatid kinetochore with mitotic spindle microtubules emanating from both spindle poles (otherwise known as merotelic attachment to the spindle)." [PMID:21306900] +synonym: "correction of merotelic kinetochore attachment, mitotic" EXACT [] +synonym: "repair of mitotic merotelic kinetochore attachment defects" EXACT [] +is_a: GO:1990598 ! repair of mitotic mono-orientation defect + +[Term] +id: GO:0098784 +name: biofilm matrix organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix." [GOC:mah] +synonym: "biofilm matrix organization and biogenesis" RELATED [GOC:dos] +is_a: GO:0030198 ! extracellular matrix organization + +[Term] +id: GO:0098785 +name: biofilm matrix assembly +namespace: biological_process +def: "A process that results in the assembly of a biofilm matrix." [GOC:mah] +is_a: GO:0085029 ! extracellular matrix assembly +is_a: GO:0098784 ! biofilm matrix organization +relationship: part_of GO:0042710 ! biofilm formation + +[Term] +id: GO:0098786 +name: biofilm matrix disassembly +namespace: biological_process +def: "A process that results in the disassembly of a biofilm matrix." [GOC:mah] +is_a: GO:0022617 ! extracellular matrix disassembly +is_a: GO:0098784 ! biofilm matrix organization + +[Term] +id: GO:0098787 +name: mRNA cleavage involved in mRNA processing +namespace: biological_process +def: "Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide." [GOC:dos] +is_a: GO:0006379 ! mRNA cleavage +intersection_of: GO:0006379 ! mRNA cleavage +intersection_of: part_of GO:0006397 ! mRNA processing +relationship: part_of GO:0006397 ! mRNA processing + +[Term] +id: GO:0098788 +name: dendritic knob +namespace: cellular_component +def: "The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium." [PMID:20801626] +synonym: "apical dendritic knob" EXACT [] +is_a: GO:0044292 ! dendrite terminus + +[Term] +id: GO:0098789 +name: pre-mRNA cleavage required for polyadenylation +namespace: biological_process +def: "The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation." [http://www.ncbi.nlm.nih.gov/books/NBK21563/#_A2878_] +synonym: "cleavage and polyadenylylation specificity factor activity" RELATED [] +synonym: "pre-mRNA cleavage factor activity" EXACT [] +is_a: GO:0098787 ! mRNA cleavage involved in mRNA processing +relationship: has_part GO:0004521 ! endoribonuclease activity +relationship: part_of GO:0031124 ! mRNA 3'-end processing + +[Term] +id: GO:0098790 +name: ncRNA transcription associated with protein coding gene TSS/TES +namespace: biological_process +def: "The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes." [PMID:20502517] +synonym: "pasRNA transcription" NARROW [PMID:20502517] +is_a: GO:0098781 ! ncRNA transcription + +[Term] +id: GO:0098791 +name: Golgi apparatus subcompartment +namespace: cellular_component +def: "A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus." [GOC:dos] +synonym: "Golgi subcompartment" EXACT [] +is_a: GO:0031984 ! organelle subcompartment +intersection_of: GO:0031984 ! organelle subcompartment +intersection_of: part_of GO:0005794 ! Golgi apparatus +relationship: part_of GO:0005794 ! Golgi apparatus + +[Term] +id: GO:0098792 +name: xenophagy +namespace: biological_process +def: "The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents." [GOC:autophagy, GOC:pad, GOC:PARL, PMID:19802565, PMID:20159618, PMID:25497060] +comment: While making xenophagy a subclass of (macro)autophagy may seem to directly contradict the definition of autophagy (literally self eating), it is clear that the same pathway is involved as in macroautophagy that doesn't target foreign material: formation of double-membrane-bounded autophagosomes that enclose a region of cytoplasm for degradation. +is_a: GO:0061912 ! selective autophagy +relationship: part_of GO:0098542 ! defense response to other organism + +[Term] +id: GO:0098793 +name: presynapse +namespace: cellular_component +def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos] +subset: goslim_synapse +synonym: "presynaptic terminal" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045202 ! synapse + +[Term] +id: GO:0098794 +name: postsynapse +namespace: cellular_component +def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos] +subset: goslim_synapse +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045202 ! synapse + +[Term] +id: GO:0098795 +name: mRNA cleavage involved in gene silencing +namespace: biological_process +def: "Cleavage of an mRNA occurring as part of the mechanism of gene silencing." [GOC:BHF, GOC:BHF_miRNA, GOC:dos] +is_a: GO:0006379 ! mRNA cleavage +intersection_of: GO:0006379 ! mRNA cleavage +intersection_of: part_of GO:0016458 ! gene silencing +relationship: part_of GO:0016458 ! gene silencing + +[Term] +id: GO:0098796 +name: membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of a membrane." [GOC:dos] +subset: goslim_metagenomics +is_a: GO:0032991 ! protein-containing complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0016020 ! membrane +relationship: part_of GO:0016020 ! membrane + +[Term] +id: GO:0098797 +name: plasma membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of the plasma membrane." [GOC:dos] +is_a: GO:0098796 ! membrane protein complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0005886 ! plasma membrane +relationship: part_of GO:0005886 ! plasma membrane + +[Term] +id: GO:0098798 +name: mitochondrial protein complex +namespace: cellular_component +def: "A protein complex that is part of a mitochondrion." [GOC:dos] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0032991 ! protein-containing complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0005739 ! mitochondrion +relationship: part_of GO:0005739 ! mitochondrion + +[Term] +id: GO:0098799 +name: outer mitochondrial membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of the outer mitochondrial membrane." [GOC:dos] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0005741 ! mitochondrial outer membrane +relationship: part_of GO:0005741 ! mitochondrial outer membrane + +[Term] +id: GO:0098800 +name: inner mitochondrial membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of the inner mitochondrial membrane." [GOC:dos] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:0098798 ! mitochondrial protein complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0005743 ! mitochondrial inner membrane +relationship: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0098801 +name: regulation of renal system process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003014 ! renal system process +relationship: regulates GO:0003014 ! renal system process + +[Term] +id: GO:0098802 +name: plasma membrane signaling receptor complex +namespace: cellular_component +def: "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor." [GOC:dos] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0043235 ! receptor complex +is_a: GO:0098797 ! plasma membrane protein complex + +[Term] +id: GO:0098803 +name: respiratory chain complex +namespace: cellular_component +def: "Any protein complex that is part of a respiratory chain." [GOC:dos] +is_a: GO:0098796 ! membrane protein complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0070469 ! respirasome +relationship: part_of GO:0070469 ! respirasome + +[Term] +id: GO:0098804 +name: non-motile cilium membrane +namespace: cellular_component +def: "The portion of the plasma membrane surrounding a non-motile cilium." [GOC:cilia, GOC:dos] +synonym: "nonmotile primary cilium membrane" RELATED [] +is_a: GO:0060170 ! ciliary membrane + +[Term] +id: GO:0098805 +name: whole membrane +namespace: cellular_component +def: "Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes." [GOC:dos] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_annotate +is_a: GO:0016020 ! membrane + +[Term] +id: GO:0098806 +name: deadenylation involved in gene silencing by miRNA +namespace: biological_process +def: "Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation." [GOC:BHF, GOC:dos, PMID:21118121, PMID:23209154] +is_a: GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening +intersection_of: GO:0000289 ! nuclear-transcribed mRNA poly(A) tail shortening +intersection_of: part_of GO:0035195 ! gene silencing by miRNA +relationship: part_of GO:0035195 ! gene silencing by miRNA + +[Term] +id: GO:0098807 +name: chloroplast thylakoid membrane protein complex +namespace: cellular_component +def: "A protein complex that is part of a chloroplast thylakoid membrane." [GOC:dos] +is_a: GO:0098796 ! membrane protein complex +intersection_of: GO:0032991 ! protein-containing complex +intersection_of: part_of GO:0009535 ! chloroplast thylakoid membrane +relationship: part_of GO:0009535 ! chloroplast thylakoid membrane + +[Term] +id: GO:0098808 +name: mRNA cap binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule." [GOC:dos] +is_a: GO:0000339 ! RNA cap binding +is_a: GO:0003729 ! mRNA binding + +[Term] +id: GO:0098809 +name: nitrite reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor." [GOC:dos, GOC:jh] +is_a: GO:0016661 ! oxidoreductase activity, acting on other nitrogenous compounds as donors + +[Term] +id: GO:0098810 +name: neurotransmitter reuptake +namespace: biological_process +def: "The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0001504 ! neurotransmitter uptake +is_a: GO:0051649 ! establishment of localization in cell +relationship: occurs_in GO:0098793 ! presynapse + +[Term] +id: GO:0098811 +name: obsolete transcriptional repressor activity, RNA polymerase II activating transcription factor binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription." [GOC:BHF, GOC:dos, GOC:rl, GOC:txnOH] +comment: The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent. +synonym: "RNA polymerase II activating transcription factor binding transcription factor activity involved in negative regulation of transcription" EXACT [] +synonym: "RNA polymerase II activating transcription factor binding transcription repressor activity" EXACT [] +synonym: "RNA polymerase II transcription repressor activity" BROAD [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16053 xsd:anyURI +is_obsolete: true +consider: GO:0001102 +consider: GO:0001227 +created_by: krc +creation_date: 2011-08-25T02:12:30Z + +[Term] +id: GO:0098812 +name: nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process +namespace: biological_process +def: "The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus." [GOC:dph, GOC:jl, GOC:tb] +synonym: "nuclear rRNA polyadenylation during polyadenylation-dependent rRNA catabolic process" RELATED [GOC:dph, GOC:tb] +synonym: "nuclear rRNA polyadenylation involved in poly(A)-dependent rRNA catabolic process" RELATED [GOC:vw] +is_a: GO:0016072 ! rRNA metabolic process +is_a: GO:0043630 ! ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process +relationship: part_of GO:0071035 ! nuclear polyadenylation-dependent rRNA catabolic process + +[Term] +id: GO:0098813 +name: nuclear chromosome segregation +namespace: biological_process +def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos] +is_a: GO:0007059 ! chromosome segregation +is_a: GO:0022402 ! cell cycle process + +[Term] +id: GO:0098814 +name: spontaneous synaptic transmission +namespace: biological_process +def: "The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential." [PMID:20200227] +comment: This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs). +subset: goslim_synapse +synonym: "basal synaptic transmission" EXACT [PMID:16899074] +is_a: GO:0007268 ! chemical synaptic transmission +intersection_of: GO:0007268 ! chemical synaptic transmission +intersection_of: has_part GO:0061669 ! spontaneous neurotransmitter secretion +relationship: has_part GO:0061669 ! spontaneous neurotransmitter secretion + +[Term] +id: GO:0098815 +name: modulation of excitatory postsynaptic potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:dos] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0042391 ! regulation of membrane potential +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0060079 ! excitatory postsynaptic potential +relationship: regulates GO:0060079 ! excitatory postsynaptic potential + +[Term] +id: GO:0098816 +name: mini excitatory postsynaptic potential +namespace: biological_process +def: "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse." [GOC:dos] +is_a: GO:0060079 ! excitatory postsynaptic potential + +[Term] +id: GO:0098817 +name: evoked excitatory postsynaptic potential +namespace: biological_process +def: "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse." [GOC:dos] +is_a: GO:0060079 ! excitatory postsynaptic potential + +[Term] +id: GO:0098818 +name: hyperpolarization of postsynaptic membrane +namespace: biological_process +def: "A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold." [GOC:dos] +is_a: GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0098819 +name: depolarization of postsynaptic membrane +namespace: biological_process +def: "A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold." [GOC:dos] +is_a: GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0098820 +name: trans-synaptic protein complex +namespace: cellular_component +def: "A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes." [PMID:20200227] +subset: goslim_synapse +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0098821 +name: BMP receptor activity +namespace: molecular_function +def: "Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity." [GOC:BHF, GOC:dos] +is_a: GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity +relationship: part_of GO:0030509 ! BMP signaling pathway + +[Term] +id: GO:0098822 +name: peptidyl-cysteine modification to L-cysteine persulfide +namespace: biological_process +def: "The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide." [PMID:11592406] +xref: RESID:AA0269 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0098823 +name: peptidyl-cysteine modification to S-amindino-L-cysteine +namespace: biological_process +def: "The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine." [RESID:AA0335] +xref: RESID:AA0335 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0098824 +name: peptidyl-cysteine sulfation +namespace: biological_process +def: "The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine." [RESID:AA0171] +xref: RESID:AA0171 +is_a: GO:0018198 ! peptidyl-cysteine modification + +[Term] +id: GO:0098825 +name: peptidyl-histidine guanylation +namespace: biological_process +def: "The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine." [RESID:AA0325] +xref: RESID:AA0325 +is_a: GO:0018117 ! protein adenylylation +is_a: GO:0018202 ! peptidyl-histidine modification + +[Term] +id: GO:0098826 +name: endoplasmic reticulum tubular network membrane +namespace: cellular_component +def: "The membrane of the endoplasmic reticulum tubular network." [PMID:16469703] +is_a: GO:0016020 ! membrane + +[Term] +id: GO:0098827 +name: endoplasmic reticulum subcompartment +namespace: cellular_component +def: "A distinct region of the endoplasmic reticulum." [GOC:dos] +is_a: GO:0031984 ! organelle subcompartment +intersection_of: GO:0031984 ! organelle subcompartment +intersection_of: part_of GO:0005783 ! endoplasmic reticulum +relationship: part_of GO:0005783 ! endoplasmic reticulum + +[Term] +id: GO:0098828 +name: modulation of inhibitory postsynaptic potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential." [GOC:dos] +synonym: "regulation of inhibitory postsynaptic potential" EXACT [] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0042391 ! regulation of membrane potential +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0060080 ! inhibitory postsynaptic potential +relationship: regulates GO:0060080 ! inhibitory postsynaptic potential + +[Term] +id: GO:0098829 +name: intestinal folate absorption +namespace: biological_process +def: "Uptake of folic into the blood by absorption from the small intestine." [GOC:BHF, GOC:dos, GOC:hal, PMID:19762432] +is_a: GO:0015884 ! folic acid transport +is_a: GO:0050892 ! intestinal absorption + +[Term] +id: GO:0098830 +name: presynaptic endosome +namespace: cellular_component +def: "An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles." [PMID:20200227, PMID:25939282] +comment: As of 2015, there is still controversy over the nature of presynaptic endosomes and their relationship to regular endosomes. See Jahne et al., 2015 (PMID:25939282) for details. +subset: goslim_synapse +is_a: GO:0005768 ! endosome +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0098831 +name: presynaptic active zone cytoplasmic component +namespace: cellular_component +def: "A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles." [GOC:dos] +subset: goslim_synapse +synonym: "cortex of presynaptic active zone" EXACT [] +synonym: "presynaptic zone cortex" EXACT [] +is_a: GO:0099738 ! cell cortex region +relationship: part_of GO:0048786 ! presynaptic active zone + +[Term] +id: GO:0098832 +name: peri-centrosomal recycling endosome +namespace: cellular_component +def: "A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes." [PMID:19696797, PMID:20820847] +is_a: GO:0055037 ! recycling endosome + +[Term] +id: GO:0098833 +name: presynaptic endocytic zone +namespace: cellular_component +def: "A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity." [PMID:17455288] +comment: May be identical to periactive zone? +subset: goslim_synapse +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0098834 +name: presynaptic endocytic zone cytoplasmic component +namespace: cellular_component +def: "The cytoplasmic component of the presynaptic endocytic zone." [GOC:dos] +subset: goslim_synapse +synonym: "cortex of presynaptic endocytic zone" EXACT [] +is_a: GO:0099738 ! cell cortex region +relationship: part_of GO:0098833 ! presynaptic endocytic zone + +[Term] +id: GO:0098835 +name: presynaptic endocytic zone membrane +namespace: cellular_component +def: "The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release." [GOC:dos] +subset: goslim_synapse +is_a: GO:0097060 ! synaptic membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane +intersection_of: part_of GO:0098833 ! presynaptic endocytic zone +relationship: part_of GO:0042734 ! presynaptic membrane +relationship: part_of GO:0098833 ! presynaptic endocytic zone + +[Term] +id: GO:0098836 +name: cytoskeleton of dendritic spine +namespace: cellular_component +def: "The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling." [PMID:24854120] +is_a: GO:0099571 ! postsynaptic cytoskeleton +intersection_of: GO:0005856 ! cytoskeleton +intersection_of: part_of GO:0043197 ! dendritic spine +relationship: part_of GO:0043197 ! dendritic spine + +[Term] +id: GO:0098837 +name: postsynaptic recycling endosome +namespace: cellular_component +def: "A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation." [PMID:20820847] +subset: goslim_synapse +synonym: "postsynaptic endosomal recycling compartment" BROAD [PMID:20820847] +synonym: "postsynaptic recycling outpost" EXACT [PMID:20820847] +is_a: GO:0055037 ! recycling endosome +is_a: GO:0098845 ! postsynaptic endosome +intersection_of: GO:0055037 ! recycling endosome +intersection_of: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0098838 +name: folate transmembrane transport +namespace: biological_process +def: "The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane." [PMID:24745983] +synonym: "folic acid transmembrane transport" RELATED [] +synonym: "reduced folate transmembrane transport" NARROW [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015884 ! folic acid transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15461 xsd:anyURI + +[Term] +id: GO:0098839 +name: postsynaptic density membrane +namespace: cellular_component +def: "The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099634 ! postsynaptic specialization membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0014069 ! postsynaptic density +intersection_of: part_of GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0014069 ! postsynaptic density + +[Term] +id: GO:0098840 +name: protein transport along microtubule +namespace: biological_process +def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607] +synonym: "microtubule-based protein transport" BROAD [] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0010970 ! transport along microtubule +is_a: GO:0099118 ! microtubule-based protein transport + +[Term] +id: GO:0098841 +name: protein localization to cell division site after cytokinesis +namespace: biological_process +def: "A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis." [PMID:25411334] +is_a: GO:0072741 ! protein localization to cell division site + +[Term] +id: GO:0098842 +name: postsynaptic early endosome +namespace: cellular_component +def: "An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling." [PMID:19603039, PMID:20820847, PMID:24727350] +comment: Commonly used markers for postsynaptic early endosomes include RAB5A and EEA1. +subset: goslim_synapse +is_a: GO:0005769 ! early endosome +is_a: GO:0098845 ! postsynaptic endosome +intersection_of: GO:0005769 ! early endosome +intersection_of: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0098843 +name: postsynaptic endocytic zone +namespace: cellular_component +def: "A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins." [PMID:17880892] +subset: goslim_synapse +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0030118 ! clathrin coat +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0098844 +name: postsynaptic endocytic zone membrane +namespace: cellular_component +def: "The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta." [PMID:17880892] +subset: goslim_synapse +is_a: GO:0097060 ! synaptic membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane +intersection_of: part_of GO:0098843 ! postsynaptic endocytic zone +relationship: part_of GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0098843 ! postsynaptic endocytic zone + +[Term] +id: GO:0098845 +name: postsynaptic endosome +namespace: cellular_component +def: "An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse." [PMID:20820847] +subset: goslim_synapse +is_a: GO:0005768 ! endosome +intersection_of: GO:0005768 ! endosome +intersection_of: part_of GO:0098794 ! postsynapse +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0098846 +name: podocyte foot +namespace: cellular_component +def: "A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms." [PMID:25324828] +synonym: "pedicel" EXACT [Wikipedia:Podocyte] +synonym: "podocyte foot process" EXACT [PMID:25324828] +synonym: "secondary podocyte projection" EXACT [] +xref: Wikipedia:Podocyte +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0098847 +name: sequence-specific single stranded DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition." [PMID:9531483] +is_a: GO:0003697 ! single-stranded DNA binding +is_a: GO:0043565 ! sequence-specific DNA binding + +[Term] +id: GO:0098848 +name: alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane." [EC:4.7.1.1, GOC:dos, GOC:ik] +synonym: "alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming)" EXACT [EC:4.7.1.1] +xref: EC:4.7.1.1 +is_a: GO:0018835 ! carbon phosphorus lyase activity + +[Term] +id: GO:0098849 +name: cellular detoxification of cadmium ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration." [GOC:dos, GOC:vw] +is_a: GO:0071585 ! detoxification of cadmium ion +is_a: GO:1990748 ! cellular detoxification +relationship: part_of GO:0071276 ! cellular response to cadmium ion + +[Term] +id: GO:0098850 +name: extrinsic component of synaptic vesicle membrane +namespace: cellular_component +def: "The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0030672 ! synaptic vesicle membrane +relationship: part_of GO:0030672 ! synaptic vesicle membrane + +[Term] +id: GO:0098851 +name: double-stranded miRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:19966796] +synonym: "miRNA duplex binding" EXACT [] +is_a: GO:0003725 ! double-stranded RNA binding + +[Term] +id: GO:0098852 +name: lytic vacuole membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell." [GOC:dos] +is_a: GO:0005774 ! vacuolar membrane + +[Term] +id: GO:0098853 +name: endoplasmic reticulum-vacuole membrane contact site +namespace: cellular_component +def: "A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes." [GOC:dos, PMID:26283797] +synonym: "endoplasmic reticulum-vacuole membrane contact site" EXACT [] +synonym: "ER-vacuole membrane contact site" EXACT [] +is_a: GO:0044232 ! organelle membrane contact site + +[Term] +id: GO:0098854 +name: podocyte primary projection +namespace: cellular_component +def: "A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot." [PMID:24309184, PMID:25324828] +synonym: "glomerular visceral epithelial cell primary projection" EXACT [] +synonym: "podocyte major process" EXACT [] +synonym: "primary podocyte process" EXACT [] +is_a: GO:0120025 ! plasma membrane bounded cell projection + +[Term] +id: GO:0098855 +name: HCN channel complex +namespace: cellular_component +alt_id: GO:1990746 +alt_id: GO:1990759 +def: "A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart." [PMID:20829353] +synonym: "HCN1 channel complex" NARROW [] +synonym: "HCN2 channel complex" NARROW [] +synonym: "HCN3 channel complex" NARROW [] +synonym: "HCN4 channel complex" NARROW [] +synonym: "K/Na hyperpolarization-activated channel 3 complex" NARROW [] +synonym: "K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex" NARROW [] +synonym: "K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex" NARROW [] +synonym: "K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex" NARROW [] +synonym: "K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex" EXACT [] +synonym: "potassium/sodium hyperpolarization-activated channel 3 complex" NARROW [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex" NARROW [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex" NARROW [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer" RELATED [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex" NARROW [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer" RELATED [] +synonym: "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex" EXACT [] +is_a: GO:0008076 ! voltage-gated potassium channel complex + +[Term] +id: GO:0098856 +name: intestinal lipid absorption +namespace: biological_process +def: "Any process in which lipids are taken up from the contents of the intestine." [GOC:dos, GOC:sl, PMID:18768481] +is_a: GO:0006869 ! lipid transport +is_a: GO:0050892 ! intestinal absorption + +[Term] +id: GO:0098857 +name: membrane microdomain +namespace: cellular_component +def: "A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it." [PMID:20044567, PMID:26253820] +is_a: GO:0098589 ! membrane region + +[Term] +id: GO:0098858 +name: actin-based cell projection +namespace: cellular_component +def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519] +is_a: GO:0120025 ! plasma membrane bounded cell projection +relationship: has_part GO:0005884 ! actin filament + +[Term] +id: GO:0098859 +name: actin filament bundle of actin-based cell projection +namespace: cellular_component +def: "A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments." [PMID:12566431, PMID:15661519] +is_a: GO:0097518 ! parallel actin filament bundle +intersection_of: GO:0097518 ! parallel actin filament bundle +intersection_of: part_of GO:0098858 ! actin-based cell projection +relationship: part_of GO:0098858 ! actin-based cell projection + +[Term] +id: GO:0098860 +name: actin filament bundle of stereocilium +namespace: cellular_component +def: "A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane." [PMID:15661519] +is_a: GO:0098859 ! actin filament bundle of actin-based cell projection +intersection_of: GO:0097518 ! parallel actin filament bundle +intersection_of: part_of GO:0032420 ! stereocilium +relationship: part_of GO:0032420 ! stereocilium + +[Term] +id: GO:0098861 +name: actin filament bundle of filopodium +namespace: cellular_component +def: "A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex." [PMID:12566431] +is_a: GO:0098859 ! actin filament bundle of actin-based cell projection +intersection_of: GO:0097518 ! parallel actin filament bundle +intersection_of: part_of GO:0030175 ! filopodium +relationship: part_of GO:0030175 ! filopodium + +[Term] +id: GO:0098862 +name: cluster of actin-based cell projections +namespace: cellular_component +def: "A cell part consisting of multiple, closely packed actin-based cell projections." [GOC:dos] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0098858 ! actin-based cell projection + +[Term] +id: GO:0098863 +name: nuclear migration by microtubule mediated pushing forces +namespace: biological_process +def: "The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules." [GOC:vw, PMID:11309419, PMID:16611238] +is_a: GO:0007097 ! nuclear migration +is_a: GO:0099098 ! microtubule polymerization based movement +is_a: GO:0099111 ! microtubule-based transport + +[Term] +id: GO:0098864 +name: modification by symbiont of host tight cell-cell junction +namespace: biological_process +def: "The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." [PMID:24287273] +is_a: GO:0044067 ! modification by symbiont of host intercellular junctions + +[Term] +id: GO:0098865 +name: modification by symbiont of host bicellular tight junctions +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet." [PMID:24287273] +is_a: GO:0098864 ! modification by symbiont of host tight cell-cell junction + +[Term] +id: GO:0098866 +name: multivesicular body fusion to apical plasma membrane +namespace: biological_process +def: "The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell." [PMID:26459596] +is_a: GO:0090174 ! organelle membrane fusion +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:1990182 ! exosomal secretion + +[Term] +id: GO:0098867 +name: intramembranous bone growth +namespace: biological_process +def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686] +is_a: GO:0098868 ! bone growth + +[Term] +id: GO:0098868 +name: bone growth +namespace: biological_process +def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos] +is_a: GO:0035265 ! organ growth + +[Term] +id: GO:0098869 +name: cellular oxidant detoxification +namespace: biological_process +def: "Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide." [GOC:dos, GOC:vw] +is_a: GO:1990748 ! cellular detoxification + +[Term] +id: GO:0098870 +name: action potential propagation +namespace: biological_process +def: "The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold." [GOC:dos] +is_a: GO:0001508 ! action potential + +[Term] +id: GO:0098871 +name: postsynaptic actin cytoskeleton +namespace: cellular_component +def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0015629 ! actin cytoskeleton +is_a: GO:0099571 ! postsynaptic cytoskeleton +intersection_of: GO:0015629 ! actin cytoskeleton +intersection_of: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0098872 +name: G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse." [GOC:dos] +subset: goslim_synapse +synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [] +synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +is_a: GO:0099583 ! neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration +intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0098873 +name: neuronal action potential back-propagation +namespace: biological_process +def: "Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma." [GOC:dos] +is_a: GO:0098870 ! action potential propagation + +[Term] +id: GO:0098874 +name: spike train +namespace: biological_process +alt_id: GO:0099603 +def: "A series of sequential, propagated action potentials occurring in a single cell." [ISBN:978-0071390118] +synonym: "burst of action potentials" EXACT [] +synonym: "spike-train" EXACT [] +is_a: GO:0042391 ! regulation of membrane potential +relationship: has_part GO:0001508 ! action potential + +[Term] +id: GO:0098875 +name: epididymosome +namespace: cellular_component +def: "A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins." [GOC:dos, GOC:mg, PMID:23177142, PMID:26112475] +is_a: GO:1990742 ! microvesicle + +[Term] +id: GO:0098876 +name: vesicle-mediated transport to the plasma membrane +namespace: biological_process +def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos] +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0098877 +name: neurotransmitter receptor transport to plasma membrane +namespace: biological_process +def: "The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles." [GOC:dos] +subset: goslim_synapse +is_a: GO:0090150 ! establishment of protein localization to membrane +is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane +is_a: GO:0099637 ! neurotransmitter receptor transport +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0098878 +name: neurotransmitter receptor complex +namespace: cellular_component +def: "Any protein complex that is capable of functioning as a neurotransmitter receptor." [GOC:dos] +is_a: GO:0098802 ! plasma membrane signaling receptor complex + +[Term] +id: GO:0098879 +name: structural constituent of postsynaptic specialization +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a postsynaptic specialization." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099186 ! structural constituent of postsynapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0099572 ! postsynaptic specialization +intersection_of: part_of GO:0098880 ! maintenance of postsynaptic specialization structure +relationship: occurs_in GO:0099572 ! postsynaptic specialization +relationship: part_of GO:0098880 ! maintenance of postsynaptic specialization structure + +[Term] +id: GO:0098880 +name: maintenance of postsynaptic specialization structure +namespace: biological_process +def: "A process which maintains the organization and the arrangement of proteins in the presynaptic specialization." [GOC:dos] +subset: goslim_synapse +is_a: GO:0097106 ! postsynaptic density organization +is_a: GO:0099558 ! maintenance of synapse structure + +[Term] +id: GO:0098881 +name: exocytic insertion of neurotransmitter receptor to plasma membrane +namespace: biological_process +def: "The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion." [GOC:aruk, GOC:bc, PMID:19503082] +subset: goslim_synapse +synonym: "neurotransmitter receptor insertion" EXACT [] +is_a: GO:0006904 ! vesicle docking involved in exocytosis +is_a: GO:0090522 ! vesicle tethering involved in exocytosis +relationship: part_of GO:0098877 ! neurotransmitter receptor transport to plasma membrane + +[Term] +id: GO:0098882 +name: structural constituent of presynaptic active zone +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a presynaptic active zone." [GOC:dos] +subset: goslim_synapse +synonym: "structural constituent of active zone" EXACT syngo_official_label [] +is_a: GO:0098918 ! structural constituent of synapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0048786 ! presynaptic active zone +intersection_of: part_of GO:0048790 ! maintenance of presynaptic active zone structure +relationship: occurs_in GO:0048786 ! presynaptic active zone +relationship: part_of GO:0048790 ! maintenance of presynaptic active zone structure + +[Term] +id: GO:0098883 +name: synapse pruning +namespace: biological_process +def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190] +subset: goslim_synapse +synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716] +synonym: "synapse disassembly" EXACT syngo_official_label [PMID:12062020] +synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190] +synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716] +is_a: GO:0050808 ! synapse organization +is_a: GO:0150146 ! cell junction disassembly + +[Term] +id: GO:0098884 +name: postsynaptic neurotransmitter receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle." [GOC:dos] +subset: goslim_synapse +synonym: "postsynaptic neurotransmitter receptor endocytosis" EXACT syngo_official_label [] +is_a: GO:0099072 ! regulation of postsynaptic membrane neurotransmitter receptor levels +is_a: GO:0099590 ! neurotransmitter receptor internalization +is_a: GO:0140239 ! postsynaptic endocytosis +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/230 xsd:anyURI + +[Term] +id: GO:0098885 +name: modification of postsynaptic actin cytoskeleton +namespace: biological_process +def: "Any process that modifies the structure of a postsynaptic actin cytoskeleton." [GOC:dos] +comment: This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones. +subset: goslim_synapse +synonym: "postsynaptic actin cytoskeleton remodelling" EXACT [] +is_a: GO:0099010 ! modification of postsynaptic structure + +[Term] +id: GO:0098886 +name: modification of dendritic spine +namespace: biological_process +def: "Any process that modifies the structure of a dendritic spine." [GOC:dos] +comment: This class does not cover assembly or disassembly of dendritic spines, only the modification/remodelling of existing ones. +is_a: GO:0099010 ! modification of postsynaptic structure + +[Term] +id: GO:0098887 +name: neurotransmitter receptor transport, endosome to postsynaptic membrane +namespace: biological_process +def: "The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles." [GOC:dos] +subset: goslim_synapse +synonym: "postsynaptic neurotransmitter receptor endosomal trafficking" BROAD [] +is_a: GO:0098969 ! neurotransmitter receptor transport to postsynaptic membrane +is_a: GO:0099639 ! neurotransmitter receptor transport, endosome to plasma membrane + +[Term] +id: GO:0098888 +name: extrinsic component of presynaptic membrane +namespace: cellular_component +def: "The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +synonym: "extrinsic component of presynaptic plasma membrane" EXACT [] +is_a: GO:0099243 ! extrinsic component of synaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane +relationship: part_of GO:0042734 ! presynaptic membrane + +[Term] +id: GO:0098889 +name: intrinsic component of presynaptic membrane +namespace: cellular_component +def: "The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to presynaptic membrane" NARROW [] +is_a: GO:0099240 ! intrinsic component of synaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane +relationship: part_of GO:0042734 ! presynaptic membrane + +[Term] +id: GO:0098890 +name: extrinsic component of postsynaptic membrane +namespace: cellular_component +def: "The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0099243 ! extrinsic component of synaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0045211 ! postsynaptic membrane + +[Term] +id: GO:0098891 +name: extrinsic component of presynaptic active zone membrane +namespace: cellular_component +def: "The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098888 ! extrinsic component of presynaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0048787 ! presynaptic active zone membrane +relationship: part_of GO:0048787 ! presynaptic active zone membrane + +[Term] +id: GO:0098892 +name: extrinsic component of postsynaptic specialization membrane +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098890 ! extrinsic component of postsynaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0099634 ! postsynaptic specialization membrane +relationship: part_of GO:0099634 ! postsynaptic specialization membrane + +[Term] +id: GO:0098893 +name: extrinsic component of postsynaptic endocytic zone +namespace: cellular_component +def: "The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098890 ! extrinsic component of postsynaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098844 ! postsynaptic endocytic zone membrane +relationship: part_of GO:0098844 ! postsynaptic endocytic zone membrane + +[Term] +id: GO:0098894 +name: extrinsic component of presynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098888 ! extrinsic component of presynaptic membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098835 ! presynaptic endocytic zone membrane +relationship: part_of GO:0098835 ! presynaptic endocytic zone membrane + +[Term] +id: GO:0098895 +name: postsynaptic endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a postsynaptic endosome." [GOC:pz] +subset: goslim_synapse +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0098845 ! postsynaptic endosome + +[Term] +id: GO:0098896 +name: postsynaptic early endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a postsynaptic early endosome." [GOC:pz] +subset: goslim_synapse +is_a: GO:0031901 ! early endosome membrane +is_a: GO:0098895 ! postsynaptic endosome membrane +relationship: part_of GO:0098842 ! postsynaptic early endosome + +[Term] +id: GO:0098897 +name: spine apparatus membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the spine apparatus." [GOC:mah] +subset: goslim_synapse +is_a: GO:0098588 ! bounding membrane of organelle +is_a: GO:0098805 ! whole membrane +relationship: part_of GO:0097444 ! spine apparatus + +[Term] +id: GO:0098898 +name: dense core granule lumen +namespace: cellular_component +def: "The volume enclosed by the dense core granule membrane." [GOC:dos] +synonym: "dense core vesicle lumen" EXACT [] +is_a: GO:0034774 ! secretory granule lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0031045 ! dense core granule +relationship: part_of GO:0031045 ! dense core granule + +[Term] +id: GO:0098899 +name: spine apparatus lumen +namespace: cellular_component +def: "The volume enclosed by the spine apparatus membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0097444 ! spine apparatus +relationship: part_of GO:0097444 ! spine apparatus + +[Term] +id: GO:0098900 +name: regulation of action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] +comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term. +is_a: GO:0042391 ! regulation of membrane potential +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0001508 ! action potential +relationship: regulates GO:0001508 ! action potential + +[Term] +id: GO:0098901 +name: regulation of cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential +relationship: regulates GO:0086001 ! cardiac muscle cell action potential + +[Term] +id: GO:0098902 +name: regulation of membrane depolarization during action potential +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential." [GOC:dos, GOC:dph, GOC:tb, ISBN:978-0-07-139011-8] +is_a: GO:0003254 ! regulation of membrane depolarization +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086010 ! membrane depolarization during action potential +relationship: regulates GO:0086010 ! membrane depolarization during action potential + +[Term] +id: GO:0098903 +name: regulation of membrane repolarization during action potential +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential." [GOC:dos, GOC:dph, GOC:tb, ISBN:978-0-07-139011-8] +is_a: GO:0060306 ! regulation of membrane repolarization +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086011 ! membrane repolarization during action potential +relationship: regulates GO:0086011 ! membrane repolarization during action potential + +[Term] +id: GO:0098904 +name: regulation of AV node cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] +synonym: "regulation of AV node cardiac muscle cell action potential" EXACT [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086016 ! AV node cell action potential +relationship: regulates GO:0086016 ! AV node cell action potential +created_by: tb +creation_date: 2011-11-10T08:58:56Z + +[Term] +id: GO:0098905 +name: regulation of bundle of His cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "regulation of bundle of His cardiac muscle cell action potential" EXACT [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086043 ! bundle of His cell action potential +relationship: regulates GO:0086043 ! bundle of His cell action potential +created_by: dph +creation_date: 2011-11-15T12:01:18Z + +[Term] +id: GO:0098906 +name: regulation of Purkinje myocyte action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086017 ! Purkinje myocyte action potential +relationship: regulates GO:0086017 ! Purkinje myocyte action potential +created_by: tb +creation_date: 2011-11-10T08:58:56Z + +[Term] +id: GO:0098907 +name: regulation of SA node cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +synonym: "regulation of SA node cardiac muscle cell action potential" EXACT [] +synonym: "regulation of SAN cardiac muscle cell action potential" EXACT [] +synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] +synonym: "regulation of sinus node cardiac muscle cell action potential" NARROW [] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086015 ! SA node cell action potential +relationship: regulates GO:0086015 ! SA node cell action potential +created_by: tb +creation_date: 2011-11-10T08:50:15Z + +[Term] +id: GO:0098908 +name: regulation of neuronal action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb] +synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] +is_a: GO:0051969 ! regulation of transmission of nerve impulse +is_a: GO:0098900 ! regulation of action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0019228 ! neuronal action potential +relationship: regulates GO:0019228 ! neuronal action potential + +[Term] +id: GO:0098909 +name: regulation of cardiac muscle cell action potential involved in regulation of contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +intersection_of: GO:0065007 ! biological regulation +intersection_of: part_of GO:0086004 ! regulation of cardiac muscle cell contraction +intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential +relationship: part_of GO:0086004 ! regulation of cardiac muscle cell contraction +created_by: tb +creation_date: 2011-11-10T07:45:11Z + +[Term] +id: GO:0098910 +name: regulation of atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0086004 ! regulation of cardiac muscle cell contraction +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086014 ! atrial cardiac muscle cell action potential +relationship: regulates GO:0086014 ! atrial cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T08:49:13Z + +[Term] +id: GO:0098911 +name: regulation of ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0086004 ! regulation of cardiac muscle cell contraction +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086005 ! ventricular cardiac muscle cell action potential +relationship: regulates GO:0086005 ! ventricular cardiac muscle cell action potential +created_by: tb +creation_date: 2011-11-10T07:59:36Z + +[Term] +id: GO:0098912 +name: membrane depolarization during atrial cardiac muscle cell action potential +namespace: biological_process +def: "The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +synonym: "atrial cardiac muscle cell depolarization" BROAD [GOC:dph, GOC:tb] +synonym: "atrial depolarization" RELATED [GOC:dph, GOC:tb] +synonym: "electrocardiogram PR interval" RELATED [GOC:dph, GOC:tb] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086014 ! atrial cardiac muscle cell action potential +relationship: part_of GO:0086014 ! atrial cardiac muscle cell action potential + +[Term] +id: GO:0098913 +name: membrane depolarization during ventricular cardiac muscle cell action potential +namespace: biological_process +def: "The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential." [GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +synonym: "electrocardiogram QRS complex" RELATED [GOC:dph, GOC:tb] +synonym: "ventricular depolarization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0051899 ! membrane depolarization +intersection_of: part_of GO:0086005 ! ventricular cardiac muscle cell action potential +relationship: part_of GO:0086005 ! ventricular cardiac muscle cell action potential + +[Term] +id: GO:0098914 +name: membrane repolarization during atrial cardiac muscle cell action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +synonym: "atrial repolarization" RELATED [GOC:dph, GOC:tb] +synonym: "electrocardiogram QRS complex" RELATED [GOC:dph, GOC:tb] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +is_a: GO:0099624 ! atrial cardiac muscle cell membrane repolarization +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086014 ! atrial cardiac muscle cell action potential +relationship: part_of GO:0086014 ! atrial cardiac muscle cell action potential + +[Term] +id: GO:0098915 +name: membrane repolarization during ventricular cardiac muscle cell action potential +namespace: biological_process +def: "The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential." [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] +synonym: "electrocardiogram T wave" RELATED [GOC:dph, GOC:tb] +synonym: "regulation of ventricular cardiac muscle repolarization" RELATED [GOC:dph, GOC:tb] +synonym: "ventricular repolarization" RELATED [GOC:dph, GOC:tb] +is_a: GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +is_a: GO:0099625 ! ventricular cardiac muscle cell membrane repolarization +intersection_of: GO:0086009 ! membrane repolarization +intersection_of: part_of GO:0086005 ! ventricular cardiac muscle cell action potential +relationship: part_of GO:0086005 ! ventricular cardiac muscle cell action potential + +[Term] +id: GO:0098916 +name: anterograde trans-synaptic signaling +namespace: biological_process +def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos] +is_a: GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0098917 +name: retrograde trans-synaptic signaling +namespace: biological_process +def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos] +is_a: GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0098918 +name: structural constituent of synapse +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a synapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005198 ! structural molecule activity +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0045202 ! synapse +intersection_of: part_of GO:0050808 ! synapse organization +relationship: occurs_in GO:0045202 ! synapse +relationship: part_of GO:0050808 ! synapse organization + +[Term] +id: GO:0098919 +name: structural constituent of postsynaptic density +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a postsynaptic density." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098879 ! structural constituent of postsynaptic specialization +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0014069 ! postsynaptic density +intersection_of: part_of GO:0099562 ! maintenance of postsynaptic density structure +relationship: occurs_in GO:0014069 ! postsynaptic density +relationship: part_of GO:0099562 ! maintenance of postsynaptic density structure + +[Term] +id: GO:0098920 +name: retrograde trans-synaptic signaling by lipid +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098917 ! retrograde trans-synaptic signaling +is_a: GO:0099541 ! trans-synaptic signaling by lipid + +[Term] +id: GO:0098921 +name: retrograde trans-synaptic signaling by endocannabinoid +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098920 ! retrograde trans-synaptic signaling by lipid +is_a: GO:0099542 ! trans-synaptic signaling by endocannabinoid + +[Term] +id: GO:0098922 +name: extrinsic component of dense core granule membrane +namespace: cellular_component +def: "The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0032127 ! dense core granule membrane +relationship: part_of GO:0032127 ! dense core granule membrane + +[Term] +id: GO:0098923 +name: retrograde trans-synaptic signaling by soluble gas +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098917 ! retrograde trans-synaptic signaling +is_a: GO:0099543 ! trans-synaptic signaling by soluble gas + +[Term] +id: GO:0098924 +name: retrograde trans-synaptic signaling by nitric oxide +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098923 ! retrograde trans-synaptic signaling by soluble gas +is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide + +[Term] +id: GO:0098925 +name: retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission +namespace: biological_process +def: "Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0098924 ! retrograde trans-synaptic signaling by nitric oxide +is_a: GO:0099555 ! trans-synaptic signaling by nitric oxide, modulating synaptic transmission + +[Term] +id: GO:0098926 +name: postsynaptic signal transduction +namespace: biological_process +def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos] +comment: Do not directly annotate. This term is intended for automatically grouping annotations to signal transduction classes extended with has_start_location/occurs_in postsynapse or one of its parts. +subset: gocheck_do_not_manually_annotate +subset: goslim_synapse +synonym: "postsynaptic signaling pathway" EXACT syngo_official_label [] +is_a: GO:0007165 ! signal transduction +relationship: part_of GO:0099536 ! synaptic signaling + +[Term] +id: GO:0098927 +name: vesicle-mediated transport between endosomal compartments +namespace: biological_process +def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome." [GOC:dos, PMID:10930469] +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0098928 +name: presynaptic signal transduction +namespace: biological_process +def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos] +comment: Do not directly annotate. This term intended for grouping. Annotate to either a subclass or to some other subclass of signal transduction extended with has_start_location/occurs_in presynapse or one of its parts. Such extensions will result in automatic annotation to this term. +subset: gocheck_do_not_manually_annotate +subset: goslim_synapse +synonym: "presynaptic signaling pathway" EXACT syngo_official_label [] +is_a: GO:0007165 ! signal transduction + +[Term] +id: GO:0098929 +name: extrinsic component of spine apparatus membrane +namespace: cellular_component +def: "The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031312 ! extrinsic component of organelle membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098897 ! spine apparatus membrane +relationship: part_of GO:0098897 ! spine apparatus membrane + +[Term] +id: GO:0098930 +name: axonal transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules in axons." [ISBN:0815316194] +subset: goslim_synapse +synonym: "axon cargo transport" EXACT [] +synonym: "axoplasmic transport" EXACT [] +xref: Wikipedia:Axoplasmic_transport +is_a: GO:0008088 ! axo-dendritic transport +relationship: occurs_in GO:0030424 ! axon + +[Term] +id: GO:0098931 +name: virion attachment to host cell flagellum +namespace: biological_process +def: "The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface." [GOC:dos, VZ:3949] +xref: VZ:3949 +is_a: GO:0019062 ! virion attachment to host cell + +[Term] +id: GO:0098932 +name: disruption by virus of host cell wall peptidoglycan during virus entry +namespace: biological_process +def: "A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry." [GOC:dos, VZ:3940] +synonym: "catabolism of host cell wall peptidoglycan by virus" EXACT [] +synonym: "degradation of host cell wall peptidoglycan by virus" EXACT [] +synonym: "degradation of host peptidoglycans during virus entry" EXACT [VZ:3940] +synonym: "disassembly by virus of host cell wall peptidoglycan" EXACT [] +xref: VZ:3940 +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0052009 ! disruption by symbiont of host cell wall +is_a: GO:0098994 ! disruption of host cell envelope during viral entry + +[Term] +id: GO:0098933 +name: disruption by symbiont of host cell envelope +namespace: biological_process +def: "The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684] +is_a: GO:0052008 ! disruption by symbiont of host cellular component +is_a: GO:0052020 ! modification by symbiont of host cell wall +is_a: GO:0052339 ! disruption by organism of cell wall of other organism involved in symbiotic interaction + +[Term] +id: GO:0098934 +name: retrograde dendritic transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098935 ! dendritic transport +relationship: occurs_in GO:0032839 ! dendrite cytoplasm + +[Term] +id: GO:0098935 +name: dendritic transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules in dendrites." [ISBN:0815316194] +subset: goslim_synapse +synonym: "dendrite cargo transport" EXACT [] +is_a: GO:0008088 ! axo-dendritic transport +relationship: occurs_in GO:0030425 ! dendrite + +[Term] +id: GO:0098936 +name: intrinsic component of postsynaptic membrane +namespace: cellular_component +def: "The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic membrane" NARROW [] +is_a: GO:0099240 ! intrinsic component of synaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0045211 ! postsynaptic membrane + +[Term] +id: GO:0098937 +name: anterograde dendritic transport +namespace: biological_process +def: "The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites." [ISBN:0815316194] +subset: goslim_synapse +is_a: GO:0098935 ! dendritic transport +relationship: occurs_in GO:0032839 ! dendrite cytoplasm + +[Term] +id: GO:0098938 +name: actin cytoskeleton of dendritic spine +namespace: cellular_component +def: "The actin cytoskeleton that is part of a dendritic spine." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098836 ! cytoskeleton of dendritic spine +is_a: GO:0098871 ! postsynaptic actin cytoskeleton +intersection_of: GO:0015629 ! actin cytoskeleton +intersection_of: part_of GO:0043197 ! dendritic spine + +[Term] +id: GO:0098939 +name: dendritic transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in nerve cell dendrites." [GOC:ai] +subset: goslim_synapse +is_a: GO:0047497 ! mitochondrion transport along microtubule +is_a: GO:0098935 ! dendritic transport +relationship: occurs_in GO:0032839 ! dendrite cytoplasm + +[Term] +id: GO:0098940 +name: anterograde trans-synaptic signaling by nitric oxide +namespace: biological_process +def: "Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098916 ! anterograde trans-synaptic signaling +is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide + +[Term] +id: GO:0098941 +name: anterograde trans-synaptic signaling by trans-synaptic protein complex +namespace: biological_process +def: "Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098916 ! anterograde trans-synaptic signaling +is_a: GO:0099545 ! trans-synaptic signaling by trans-synaptic complex + +[Term] +id: GO:0098942 +name: retrograde trans-synaptic signaling by trans-synaptic protein complex +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098917 ! retrograde trans-synaptic signaling +is_a: GO:0099545 ! trans-synaptic signaling by trans-synaptic complex + +[Term] +id: GO:0098943 +name: neurotransmitter receptor transport, postsynaptic endosome to lysosome +namespace: biological_process +def: "The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation." [GOC:dos] +subset: goslim_synapse +synonym: "postsynaptic neurotransmitter receptor endosomal trafficking" BROAD [] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0061462 ! protein localization to lysosome +is_a: GO:0072666 ! establishment of protein localization to vacuole +is_a: GO:0099637 ! neurotransmitter receptor transport + +[Term] +id: GO:0098944 +name: postsynaptic recycling endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a postsynaptic recycling endosome." [GOC:pz] +subset: goslim_synapse +is_a: GO:0098895 ! postsynaptic endosome membrane +relationship: part_of GO:0098837 ! postsynaptic recycling endosome + +[Term] +id: GO:0098945 +name: intrinsic component of presynaptic active zone membrane +namespace: cellular_component +def: "The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to presynaptic acive zone membrane" NARROW [] +is_a: GO:0098889 ! intrinsic component of presynaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0048787 ! presynaptic active zone membrane +relationship: part_of GO:0048787 ! presynaptic active zone membrane + +[Term] +id: GO:0098946 +name: intrinsic component of presynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to presynaptic acive zone membrane" NARROW [] +is_a: GO:0098889 ! intrinsic component of presynaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098835 ! presynaptic endocytic zone membrane +relationship: part_of GO:0098835 ! presynaptic endocytic zone membrane + +[Term] +id: GO:0098947 +name: intrinsic component of postsynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic acive zone membrane" NARROW [] +is_a: GO:0098936 ! intrinsic component of postsynaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098844 ! postsynaptic endocytic zone membrane +relationship: part_of GO:0098844 ! postsynaptic endocytic zone membrane + +[Term] +id: GO:0098948 +name: intrinsic component of postsynaptic specialization membrane +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic specialization membrane" NARROW [] +is_a: GO:0098936 ! intrinsic component of postsynaptic membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0099634 ! postsynaptic specialization membrane +relationship: part_of GO:0099634 ! postsynaptic specialization membrane + +[Term] +id: GO:0098949 +name: intrinsic component of postsynaptic endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic endosome membrane" NARROW [] +is_a: GO:0031302 ! intrinsic component of endosome membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098895 ! postsynaptic endosome membrane +relationship: part_of GO:0098895 ! postsynaptic endosome membrane + +[Term] +id: GO:0098950 +name: intrinsic component of postsynaptic early endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic early endosome membrane" NARROW [] +is_a: GO:0098949 ! intrinsic component of postsynaptic endosome membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098896 ! postsynaptic early endosome membrane +relationship: part_of GO:0098896 ! postsynaptic early endosome membrane + +[Term] +id: GO:0098951 +name: intrinsic component of postsynaptic recycling endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic recycling endosome membrane" EXACT [] +is_a: GO:0098949 ! intrinsic component of postsynaptic endosome membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098944 ! postsynaptic recycling endosome membrane +relationship: part_of GO:0098944 ! postsynaptic recycling endosome membrane + +[Term] +id: GO:0098952 +name: intrinsic component of spine apparatus membrane +namespace: cellular_component +def: "The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to spine apparatus membrane" EXACT [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098897 ! spine apparatus membrane +relationship: part_of GO:0098897 ! spine apparatus membrane + +[Term] +id: GO:0098953 +name: receptor diffusion trapping +namespace: biological_process +def: "The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix." [PMID:18832033] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0051668 ! localization within membrane +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery +relationship: occurs_in GO:0005886 ! plasma membrane + +[Term] +id: GO:0098954 +name: presynaptic endosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a presynaptic endosome." [GOC:pz] +subset: goslim_synapse +is_a: GO:0010008 ! endosome membrane +relationship: part_of GO:0098830 ! presynaptic endosome + +[Term] +id: GO:0098955 +name: intrinsic component of presynaptic endosome membrane +namespace: cellular_component +def: "The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to presynaptic endosome membrane" EXACT [] +is_a: GO:0031302 ! intrinsic component of endosome membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098954 ! presynaptic endosome membrane +relationship: part_of GO:0098954 ! presynaptic endosome membrane + +[Term] +id: GO:0098956 +name: intrinsic component of dense core granule membrane +namespace: cellular_component +def: "The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +synonym: "intrinsic to dense core granule membrane" EXACT [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0032127 ! dense core granule membrane +relationship: part_of GO:0032127 ! dense core granule membrane + +[Term] +id: GO:0098957 +name: anterograde axonal transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse." [GOC:dos] +subset: goslim_synapse +synonym: "anterograde axon transport of mitochondria" EXACT [] +is_a: GO:0008089 ! anterograde axonal transport +is_a: GO:0019896 ! axonal transport of mitochondrion + +[Term] +id: GO:0098958 +name: retrograde axonal transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse." [GOC:dos] +subset: goslim_synapse +synonym: "retrograde axon transport of mitochondria" EXACT [] +is_a: GO:0008090 ! retrograde axonal transport +is_a: GO:0019896 ! axonal transport of mitochondrion + +[Term] +id: GO:0098959 +name: retrograde dendritic transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse." [GOC:dos] +subset: goslim_synapse +synonym: "retrograde dendrite transport of mitochondria" EXACT [] +is_a: GO:0098939 ! dendritic transport of mitochondrion + +[Term] +id: GO:0098960 +name: postsynaptic neurotransmitter receptor activity +namespace: molecular_function +def: "Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission." [GOC:dos, GOC:signaling] +synonym: "neurotransmitter receptor activity involved in chemical synaptic transmission" EXACT [] +is_a: GO:0030594 ! neurotransmitter receptor activity +intersection_of: GO:0030594 ! neurotransmitter receptor activity +intersection_of: part_of GO:0007268 ! chemical synaptic transmission +relationship: occurs_in GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0099565 ! chemical synaptic transmission, postsynaptic + +[Term] +id: GO:0098961 +name: dendritic transport of ribonucleoprotein complex +namespace: biological_process +def: "The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites." [GOC:dos] +subset: goslim_synapse +synonym: "dendritic transport of RNP complex" EXACT [] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0050658 ! RNA transport +is_a: GO:0098935 ! dendritic transport +is_a: GO:0099640 ! axo-dendritic protein transport +relationship: occurs_in GO:0032839 ! dendrite cytoplasm + +[Term] +id: GO:0098962 +name: regulation of postsynaptic neurotransmitter receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031644 ! regulation of nervous system process +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0099601 ! regulation of neurotransmitter receptor activity +intersection_of: GO:0065009 ! regulation of molecular function +intersection_of: regulates GO:0098960 ! postsynaptic neurotransmitter receptor activity +relationship: regulates GO:0098960 ! postsynaptic neurotransmitter receptor activity + +[Term] +id: GO:0098963 +name: dendritic transport of messenger ribonucleoprotein complex +namespace: biological_process +def: "The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites." [GOC:dos] +subset: goslim_synapse +synonym: "dendritic transport of mRNA RNP complex" EXACT [] +is_a: GO:0098961 ! dendritic transport of ribonucleoprotein complex + +[Term] +id: GO:0098964 +name: anterograde dendritic transport of messenger ribonucleoprotein complex +namespace: biological_process +def: "The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse." [GOC:dos] +subset: goslim_synapse +synonym: "anterograde dendritic transport of mRNA RNP complex" EXACT [] +is_a: GO:0062237 ! protein localization to postsynapse +is_a: GO:0098937 ! anterograde dendritic transport +is_a: GO:0098963 ! dendritic transport of messenger ribonucleoprotein complex + +[Term] +id: GO:0098965 +name: extracellular matrix of synaptic cleft +namespace: cellular_component +def: "The portion of the extracellular matrix that lies within the synaptic cleft." [GOC:dos] +subset: goslim_synapse +synonym: "ECM of synaptic cleft" EXACT [] +synonym: "synaptic cleft ECM" EXACT [] +is_a: GO:0062023 ! collagen-containing extracellular matrix +relationship: part_of GO:0043083 ! synaptic cleft +relationship: part_of GO:0099535 ! synapse-associated extracellular matrix + +[Term] +id: GO:0098966 +name: perisynaptic extracellular matrix +namespace: cellular_component +def: "The portion of the extracellular matrix that lies within the perisynaptic space." [GOC:dos] +subset: goslim_synapse +synonym: "extrasynaptic extracellular matrix" EXACT [] +synonym: "perisynaptic ECM" EXACT [] +is_a: GO:0062023 ! collagen-containing extracellular matrix +relationship: part_of GO:0099535 ! synapse-associated extracellular matrix +relationship: part_of GO:0099544 ! perisynaptic space + +[Term] +id: GO:0098967 +name: exocytic insertion of neurotransmitter receptor to postsynaptic membrane +namespace: biological_process +def: "The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion." [PMID:19503082] +subset: goslim_synapse +is_a: GO:0006887 ! exocytosis +is_a: GO:0099072 ! regulation of postsynaptic membrane neurotransmitter receptor levels +intersection_of: GO:0006887 ! exocytosis +intersection_of: part_of GO:0098969 ! neurotransmitter receptor transport to postsynaptic membrane +relationship: part_of GO:0098969 ! neurotransmitter receptor transport to postsynaptic membrane + +[Term] +id: GO:0098968 +name: neurotransmitter receptor transport postsynaptic membrane to endosome +namespace: biological_process +def: "Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome." [GOC:dos] +subset: goslim_synapse +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0062237 ! protein localization to postsynapse +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0097120 ! receptor localization to synapse +is_a: GO:0099637 ! neurotransmitter receptor transport +is_a: GO:1902946 ! protein localization to early endosome + +[Term] +id: GO:0098969 +name: neurotransmitter receptor transport to postsynaptic membrane +namespace: biological_process +def: "The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles." [GOC:dos] +subset: goslim_synapse +is_a: GO:0097120 ! receptor localization to synapse +is_a: GO:0098877 ! neurotransmitter receptor transport to plasma membrane +is_a: GO:0099072 ! regulation of postsynaptic membrane neurotransmitter receptor levels +is_a: GO:1903540 ! establishment of protein localization to postsynaptic membrane + +[Term] +id: GO:0098970 +name: postsynaptic neurotransmitter receptor diffusion trapping +namespace: biological_process +def: "The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization." [PMID:18832033] +subset: goslim_synapse +is_a: GO:0099628 ! neurotransmitter receptor diffusion trapping +is_a: GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane +relationship: occurs_in GO:0045211 ! postsynaptic membrane +relationship: occurs_in GO:0099634 ! postsynaptic specialization membrane + +[Term] +id: GO:0098971 +name: anterograde dendritic transport of neurotransmitter receptor complex +namespace: biological_process +def: "The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0062237 ! protein localization to postsynapse +is_a: GO:0097120 ! receptor localization to synapse +is_a: GO:0098937 ! anterograde dendritic transport +is_a: GO:0099637 ! neurotransmitter receptor transport +is_a: GO:0099640 ! axo-dendritic protein transport + +[Term] +id: GO:0098972 +name: anterograde dendritic transport of mitochondrion +namespace: biological_process +def: "The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098937 ! anterograde dendritic transport +is_a: GO:0098939 ! dendritic transport of mitochondrion + +[Term] +id: GO:0098973 +name: structural constituent of postsynaptic actin cytoskeleton +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005200 ! structural constituent of cytoskeleton +is_a: GO:0099186 ! structural constituent of postsynapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0098871 ! postsynaptic actin cytoskeleton +intersection_of: part_of GO:0098974 ! postsynaptic actin cytoskeleton organization +relationship: occurs_in GO:0098871 ! postsynaptic actin cytoskeleton +relationship: part_of GO:0098974 ! postsynaptic actin cytoskeleton organization + +[Term] +id: GO:0098974 +name: postsynaptic actin cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0030036 ! actin cytoskeleton organization +is_a: GO:0099188 ! postsynaptic cytoskeleton organization + +[Term] +id: GO:0098975 +name: postsynapse of neuromuscular junction +namespace: cellular_component +def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502] +is_a: GO:0098794 ! postsynapse +relationship: part_of GO:0031594 ! neuromuscular junction + +[Term] +id: GO:0098976 +name: excitatory chemical synaptic transmission +namespace: biological_process +def: "Synaptic transmission that results in an excitatory postsynaptic potential." [GOC:dos] +is_a: GO:0007268 ! chemical synaptic transmission +intersection_of: GO:0007268 ! chemical synaptic transmission +intersection_of: has_part GO:0060079 ! excitatory postsynaptic potential +relationship: has_part GO:0060079 ! excitatory postsynaptic potential + +[Term] +id: GO:0098977 +name: inhibitory chemical synaptic transmission +namespace: biological_process +def: "Synaptic transmission that results in an inhibitory postsynaptic potential." [GOC:dos] +is_a: GO:0007268 ! chemical synaptic transmission +intersection_of: GO:0007268 ! chemical synaptic transmission +intersection_of: has_part GO:0060080 ! inhibitory postsynaptic potential +relationship: has_part GO:0060080 ! inhibitory postsynaptic potential + +[Term] +id: GO:0098978 +name: glutamatergic synapse +namespace: cellular_component +def: "A synapse that uses glutamate as a neurotransmitter." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0098979 +name: polyadic synapse +namespace: cellular_component +def: "A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems." [PMID:26780543] +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0098980 +name: presynaptic density +namespace: cellular_component +def: "An electron dense specialization of the presynaptic active zone cytoskeleton." [GOC:dos, PMID:26780543] +is_a: GO:0048788 ! cytoskeleton of presynaptic active zone + +[Term] +id: GO:0098981 +name: cholinergic synapse +namespace: cellular_component +def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0098982 +name: GABA-ergic synapse +namespace: cellular_component +def: "A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0098983 +name: symmetric, GABA-ergic, inhibitory synapse +namespace: cellular_component +def: "A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials." [GOC:dos] +is_a: GO:0032280 ! symmetric synapse +is_a: GO:0060077 ! inhibitory synapse +is_a: GO:0098982 ! GABA-ergic synapse + +[Term] +id: GO:0098984 +name: neuron to neuron synapse +namespace: cellular_component +def: "A synapse in which pre and post-synaptic cells are neurons." [GOC:dos] +is_a: GO:0045202 ! synapse + +[Term] +id: GO:0098985 +name: asymmetric, glutamatergic, excitatory synapse +namespace: cellular_component +def: "A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials." [GOC:dos] +is_a: GO:0032279 ! asymmetric synapse +is_a: GO:0060076 ! excitatory synapse +is_a: GO:0098978 ! glutamatergic synapse + +[Term] +id: GO:0098986 +name: T-bar +namespace: cellular_component +def: "A T-shaped presynpatic density. These are common in arhropod central nervous systems." [GOC:dos, PMID:26780543] +is_a: GO:0098980 ! presynaptic density + +[Term] +id: GO:0098987 +name: regulation of modification of synapse structure, modulating synaptic transmission +namespace: biological_process +def: "Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:1905244 ! regulation of modification of synaptic structure +intersection_of: GO:1905244 ! regulation of modification of synaptic structure +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0098988 +name: G protein-coupled glutamate receptor activity +namespace: molecular_function +def: "Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity." [GOC:dos] +synonym: "G-protein coupled glutamate receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0008066 ! glutamate receptor activity + +[Term] +id: GO:0098989 +name: NMDA selective glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:dos, ISBN:9780071120005] +is_a: GO:0035235 ! ionotropic glutamate receptor signaling pathway + +[Term] +id: GO:0098990 +name: AMPA selective glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:dos, ISBN:9780071120005] +subset: goslim_synapse +is_a: GO:0035235 ! ionotropic glutamate receptor signaling pathway + +[Term] +id: GO:0098991 +name: kainate selective glutamate receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:9780071120005] +subset: goslim_synapse +is_a: GO:0035235 ! ionotropic glutamate receptor signaling pathway + +[Term] +id: GO:0098992 +name: neuronal dense core vesicle +namespace: cellular_component +def: "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." [GOC:dos, ISBN:978-0-07-181001-2, Wikipedia:Neuropeptide&oldid=713905176] +subset: goslim_synapse +is_a: GO:0031045 ! dense core granule + +[Term] +id: GO:0098993 +name: anchored component of synaptic vesicle membrane +namespace: cellular_component +def: "The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0098563 ! intrinsic component of synaptic vesicle membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0030672 ! synaptic vesicle membrane + +[Term] +id: GO:0098994 +name: disruption of host cell envelope during viral entry +namespace: biological_process +def: "The disruption of host cell envelope by viral proteins during virus entry." [GOC:dos] +xref: VZ:3938 +is_a: GO:0098933 ! disruption by symbiont of host cell envelope +intersection_of: GO:0098933 ! disruption by symbiont of host cell envelope +intersection_of: part_of GO:0046718 ! viral entry into host cell +relationship: part_of GO:0046718 ! viral entry into host cell + +[Term] +id: GO:0098995 +name: disruption by virus of host envelope lipopolysaccharide during virus entry +namespace: biological_process +def: "The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides." [GOC:dos, VZ:3940] +synonym: "degradation of host cell envelope lipopolysaccharide during viral entry" EXACT [] +synonym: "degradation of host lipopolysaccharide during virus entry" EXACT [VZ:3940] +synonym: "disassembly by virus of outer membrane lipopolysaccharide during viral entry" NARROW [] +xref: VZ:3939 +is_a: GO:0019048 ! modulation by virus of host process +is_a: GO:0052009 ! disruption by symbiont of host cell wall +is_a: GO:0098994 ! disruption of host cell envelope during viral entry + +[Term] +id: GO:0098996 +name: disruption of host cell glycocalyx during viral entry +namespace: biological_process +def: "The disruption of host cell glycocalyx by viral proteins during virus entry." [GOC:dos] +synonym: "catabolism of host glycocalyx during viral entry" EXACT [] +synonym: "degradation of host capsule during virus entry" EXACT [VZ:3896] +synonym: "degradation of host glycocalyx during viral entry" EXACT [] +synonym: "disassembly of glycocalyx during viral entry" EXACT [] +xref: VZ:3938 +is_a: GO:0098994 ! disruption of host cell envelope during viral entry + +[Term] +id: GO:0098997 +name: fusion of virus membrane with host outer membrane +namespace: biological_process +def: "Fusion of a viral membrane with the host cell outer membrane during viral entry." [GOC:dos, VZ:3941] +synonym: "fusion of viral membrane with host outer membrane" RELATED [GOC:dos, VZ:3941] +synonym: "viral envelope fusion" BROAD [] +synonym: "viral envelope fusion with host outer membrane" EXACT [] +synonym: "viral penetration via membrane fusion" BROAD [] +synonym: "viral-cell fusion molecule activity" RELATED [] +xref: VZ:3941 "Fusion of virus membrane with host cell membrane" +is_a: GO:0019064 ! fusion of virus membrane with host plasma membrane + +[Term] +id: GO:0098998 +name: extrinsic component of postsynaptic early endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098999 ! extrinsic component of postsynaptic endosome membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098896 ! postsynaptic early endosome membrane +relationship: part_of GO:0098896 ! postsynaptic early endosome membrane + +[Term] +id: GO:0098999 +name: extrinsic component of postsynaptic endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0031313 ! extrinsic component of endosome membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098895 ! postsynaptic endosome membrane +relationship: part_of GO:0098895 ! postsynaptic endosome membrane + +[Term] +id: GO:0099000 +name: viral genome ejection through host cell envelope, contractile tail mechanism +namespace: biological_process +def: "Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope." [GOC:dos, PMID:26283379, VZ:3950] +synonym: "viral contractile tail ejection system" EXACT [VZ:3950] +xref: VZ:3950 +is_a: GO:0039678 ! viral genome ejection through host cell envelope + +[Term] +id: GO:0099001 +name: viral genome ejection through host cell envelope, long flexible tail mechanism +namespace: biological_process +def: "Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm." [GOC:dos, PMID:22297512, VZ:3952] +synonym: "viral long flexible tail ejection system" EXACT [VZ:3952] +xref: VZ:3952 +is_a: GO:0039678 ! viral genome ejection through host cell envelope +is_a: GO:0046794 ! transport of virus + +[Term] +id: GO:0099002 +name: viral genome ejection through host cell envelope, short tail mechanism +namespace: biological_process +def: "Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties." [GOC:dos, PMID:22297513, VZ:3954] +synonym: "viral short tail ejection system" EXACT [VZ:3954] +xref: VZ:3954 +is_a: GO:0039678 ! viral genome ejection through host cell envelope +is_a: GO:0046794 ! transport of virus + +[Term] +id: GO:0099003 +name: vesicle-mediated transport in synapse +namespace: biological_process +def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0016192 ! vesicle-mediated transport +intersection_of: GO:0016192 ! vesicle-mediated transport +intersection_of: occurs_in GO:0045202 ! synapse +relationship: occurs_in GO:0045202 ! synapse + +[Term] +id: GO:0099004 +name: calmodulin dependent kinase signaling pathway +namespace: biological_process +def: "Any signal transduction pathway involving calmodulin dependent kinase activity." [GOC:dos] +synonym: "CAMK signaling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: has_part GO:0004683 ! calmodulin-dependent protein kinase activity +relationship: has_part GO:0004683 ! calmodulin-dependent protein kinase activity + +[Term] +id: GO:0099005 +name: extrinsic component of postsynaptic recycling endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098999 ! extrinsic component of postsynaptic endosome membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098944 ! postsynaptic recycling endosome membrane +relationship: part_of GO:0098944 ! postsynaptic recycling endosome membrane + +[Term] +id: GO:0099006 +name: viral entry via permeabilization of endosomal membrane +namespace: biological_process +def: "The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen." [PMID:15329727, PMID:25055856, VZ:985] +synonym: "viral penetration via permeabilization of host membrane" BROAD [vz:985] +xref: VZ:985 +is_a: GO:0140267 ! viral entry via permeabilization of host membrane + +[Term] +id: GO:0099007 +name: extrinsic component of presynaptic endosome membrane +namespace: cellular_component +def: "The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0031313 ! extrinsic component of endosome membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098954 ! presynaptic endosome membrane +relationship: part_of GO:0098954 ! presynaptic endosome membrane + +[Term] +id: GO:0099008 +name: viral entry via permeabilization of inner membrane +namespace: biological_process +def: "The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane." [PMID:15795287, PMID:20427561, VZ:985] +synonym: "viral penetration via permeabilization of host membrane" BROAD [vz:985] +xref: VZ:985 +is_a: GO:0140267 ! viral entry via permeabilization of host membrane + +[Term] +id: GO:0099009 +name: viral genome circularization +namespace: biological_process +def: "The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities." [PMID:11894948, PMID:15489417, PMID:19523475, PMID:319596, VZ:3968] +xref: VZ:3968 +is_a: GO:0016032 ! viral process + +[Term] +id: GO:0099010 +name: modification of postsynaptic structure +namespace: biological_process +def: "Any process that modifies the structure of a postsynapse." [GOC:dos] +comment: This class does not cover assembly or disassembly of postsynapses, only the modification/remodelling of existing ones. +subset: goslim_synapse +synonym: "synapse remodelling" BROAD [] +is_a: GO:0099563 ! modification of synaptic structure + +[Term] +id: GO:0099011 +name: neuronal dense core vesicle exocytosis +namespace: biological_process +def: "The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels." [GOC:kmv, PMID:17553987, PMID:24653208] +is_a: GO:1990504 ! dense core granule exocytosis +created_by: kmv + +[Term] +id: GO:0099012 +name: neuronal dense core vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a neuronal dense core vesicle." [GOC:dos] +subset: goslim_synapse +is_a: GO:0032127 ! dense core granule membrane +relationship: part_of GO:0098992 ! neuronal dense core vesicle + +[Term] +id: GO:0099013 +name: neuronal dense core vesicle lumen +namespace: cellular_component +def: "The volume enclosed by a neuronal dense core vesicle membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098898 ! dense core granule lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0098992 ! neuronal dense core vesicle +relationship: part_of GO:0098992 ! neuronal dense core vesicle + +[Term] +id: GO:0099014 +name: neuronal dense core vesicle organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." [GOC:dos] +is_a: GO:0061109 ! dense core granule organization + +[Term] +id: GO:0099015 +name: degradation of host chromosome by virus +namespace: biological_process +def: "The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis." [PMID:163355, PMID:335083, PMID:3972821, PMID:5263754, VZ:3947] +xref: VZ:3947 +is_a: GO:0039637 ! catabolism by virus of host DNA + +[Term] +id: GO:0099016 +name: DNA end degradation evasion by virus +namespace: biological_process +def: "Any process, either active or passive, by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases." [GOC:dos, VZ:3963] +xref: VZ:3963 +is_a: GO:0019049 ! mitigation of host defenses by virus + +[Term] +id: GO:0099017 +name: maintenance of protein localization at cell tip +namespace: biological_process +def: "Any process in which localization of a protein is maintained at the cell tip." [GOC:dos, GOC:vw, PMID:12894167] +synonym: "maintenance of protein location at cell tip" EXACT [] +is_a: GO:0032507 ! maintenance of protein location in cell +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0051286 ! cell tip +relationship: occurs_in GO:0051286 ! cell tip +property_value: http://purl.org/dc/elements/1.1/creator "dos" xsd:string +property_value: http://purl.org/dc/elements/1.1/date 2016-06-30T15:17:41Z xsd:dateTime + +[Term] +id: GO:0099018 +name: restriction-modification system evasion by virus +namespace: biological_process +def: "Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction." [PMID:20348932, PMID:23979432, PMID:24123737, VZ:3966] +xref: VZ:3966 +is_a: GO:0019049 ! mitigation of host defenses by virus + +[Term] +id: GO:0099019 +name: maintenance of protein localization at growing cell tip +namespace: biological_process +def: "Any process in which localization of a protein is maintained at the growing cell tip." [GOC:dos, GOC:vw, PMID:24146635] +synonym: "maintenance of protein location at growing cell tip" EXACT [] +is_a: GO:0099017 ! maintenance of protein localization at cell tip +intersection_of: GO:0045185 ! maintenance of protein location +intersection_of: occurs_in GO:0035838 ! growing cell tip +relationship: occurs_in GO:0035838 ! growing cell tip +created_by: dos +creation_date: 2016-06-30T15:17:41Z + +[Term] +id: GO:0099020 +name: perinuclear endoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the perinuclear endoplasmic reticulum." [GOC:dos, GOC:vw] +is_a: GO:0005788 ! endoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0097038 ! perinuclear endoplasmic reticulum +relationship: part_of GO:0097038 ! perinuclear endoplasmic reticulum + +[Term] +id: GO:0099021 +name: cortical endoplasmic reticulum lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of the cortical endoplasmic reticulum." [GOC:dos, GOC:vw] +is_a: GO:0005788 ! endoplasmic reticulum lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0032541 ! cortical endoplasmic reticulum +relationship: part_of GO:0032541 ! cortical endoplasmic reticulum + +[Term] +id: GO:0099022 +name: vesicle tethering +namespace: biological_process +def: "The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion." [PMID:27243008] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0006903 ! vesicle targeting + +[Term] +id: GO:0099023 +name: vesicle tethering complex +namespace: cellular_component +def: "Any protein complex that plays a role in vesicle tethering." [GOC:dos, GOC:vw, PMID:27243008] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0099024 +name: plasma membrane invagination +namespace: biological_process +def: "An infolding of the plasma membrane." [GOC:dos, GOC:vw] +is_a: GO:0010324 ! membrane invagination + +[Term] +id: GO:0099025 +name: anchored component of postsynaptic membrane +namespace: cellular_component +def: "The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098936 ! intrinsic component of postsynaptic membrane +is_a: GO:0099144 ! anchored component of synaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane + +[Term] +id: GO:0099026 +name: anchored component of presynaptic membrane +namespace: cellular_component +def: "The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +synonym: "anchored component of presynaptic plasma membrane" EXACT [] +is_a: GO:0098889 ! intrinsic component of presynaptic membrane +is_a: GO:0099144 ! anchored component of synaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane + +[Term] +id: GO:0099027 +name: anchored component of presynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098946 ! intrinsic component of presynaptic endocytic zone membrane +is_a: GO:0099026 ! anchored component of presynaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098835 ! presynaptic endocytic zone membrane + +[Term] +id: GO:0099028 +name: anchored component of postynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098947 ! intrinsic component of postsynaptic endocytic zone membrane +is_a: GO:0099025 ! anchored component of postsynaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098844 ! postsynaptic endocytic zone membrane + +[Term] +id: GO:0099029 +name: anchored component of presynaptic active zone membrane +namespace: cellular_component +def: "The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098945 ! intrinsic component of presynaptic active zone membrane +is_a: GO:0099026 ! anchored component of presynaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0048787 ! presynaptic active zone membrane + +[Term] +id: GO:0099030 +name: anchored component of postsynaptic specialization membrane +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098948 ! intrinsic component of postsynaptic specialization membrane +is_a: GO:0099025 ! anchored component of postsynaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0099634 ! postsynaptic specialization membrane + +[Term] +id: GO:0099031 +name: anchored component of postsynaptic density membrane +namespace: cellular_component +def: "The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099030 ! anchored component of postsynaptic specialization membrane +is_a: GO:0099146 ! intrinsic component of postsynaptic density membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098839 ! postsynaptic density membrane + +[Term] +id: GO:0099032 +name: anchored component of postsynaptic early endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098950 ! intrinsic component of postsynaptic early endosome membrane +is_a: GO:0099034 ! anchored component of postsynaptic endosome membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098896 ! postsynaptic early endosome membrane + +[Term] +id: GO:0099033 +name: anchored component of postsynaptic recycling endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098951 ! intrinsic component of postsynaptic recycling endosome membrane +is_a: GO:0099034 ! anchored component of postsynaptic endosome membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098944 ! postsynaptic recycling endosome membrane + +[Term] +id: GO:0099034 +name: anchored component of postsynaptic endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0098949 ! intrinsic component of postsynaptic endosome membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098895 ! postsynaptic endosome membrane + +[Term] +id: GO:0099035 +name: anchored component of spine apparatus membrane +namespace: cellular_component +def: "The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0098952 ! intrinsic component of spine apparatus membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098897 ! spine apparatus membrane + +[Term] +id: GO:0099036 +name: anchored component of neuronal dense core vesicle membrane +namespace: cellular_component +def: "The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0098675 ! intrinsic component of neuronal dense core vesicle membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0099012 ! neuronal dense core vesicle membrane + +[Term] +id: GO:0099037 +name: anchored component of presynaptic endosome membrane +namespace: cellular_component +def: "The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031225 ! anchored component of membrane +is_a: GO:0098955 ! intrinsic component of presynaptic endosome membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0098954 ! presynaptic endosome membrane + +[Term] +id: GO:0099038 +name: ceramide floppase activity +namespace: molecular_function +def: "Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [GOC:BHF, GOC:dos, GOC:rl] +synonym: "ATP-dependent ceramide transporter activity" BROAD [] +synonym: "ATPase-coupled ceramide transporter activity" BROAD [] +synonym: "ceramide floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +synonym: "ceramide-translocating ATPase activity" BROAD [] +is_a: GO:0046623 ! sphingolipid floppase activity +relationship: part_of GO:0099040 ! ceramide translocation + +[Term] +id: GO:0099039 +name: sphingolipid translocation +namespace: biological_process +def: "The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet." [GOC:BHF, GOC:rl] +is_a: GO:0034204 ! lipid translocation +is_a: GO:0071705 ! nitrogen compound transport + +[Term] +id: GO:0099040 +name: ceramide translocation +namespace: biological_process +def: "The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet." [GOC:BHF, GOC:rl] +is_a: GO:0035627 ! ceramide transport +is_a: GO:0099039 ! sphingolipid translocation + +[Term] +id: GO:0099041 +name: vesicle tethering to Golgi +namespace: biological_process +def: "The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion." [PMID:27243008] +is_a: GO:0099022 ! vesicle tethering +created_by: tb +creation_date: 2013-01-08T15:07:50Z + +[Term] +id: GO:0099042 +name: nucleation of clathrin-coated pit +namespace: biological_process +def: "The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit." [GOC:dos, GOC:vw, PMID:21779028] +is_a: GO:0099024 ! plasma membrane invagination +relationship: part_of GO:0072583 ! clathrin-dependent endocytosis + +[Term] +id: GO:0099043 +name: cargo loading involved in clathrin-dependent endocytosis +namespace: biological_process +def: "Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat." [GOC:dos, GOC:lb, GOC:vw, PMID:21779028] +is_a: GO:0035652 ! clathrin-coated vesicle cargo loading +intersection_of: GO:0035652 ! clathrin-coated vesicle cargo loading +intersection_of: part_of GO:0072583 ! clathrin-dependent endocytosis +relationship: part_of GO:0072583 ! clathrin-dependent endocytosis + +[Term] +id: GO:0099044 +name: vesicle tethering to endoplasmic reticulum +namespace: biological_process +def: "The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion." [PMID:27243008] +is_a: GO:0099022 ! vesicle tethering +created_by: tb +creation_date: 2013-01-08T15:07:50Z + +[Term] +id: GO:0099045 +name: viral extrusion +namespace: biological_process +def: "The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded." [PMID:2024582831, VZ:3951] +xref: VZ:3951 +is_a: GO:0046753 ! non-lytic viral release + +[Term] +id: GO:0099046 +name: clearance of foreign intracellular nucleic acids +namespace: biological_process +def: "A defense process that protects an organism from DNA or RNA from an invading organism." [GO:dos] +is_a: GO:0098542 ! defense response to other organism + +[Term] +id: GO:0099047 +name: clearance of foreign intracellular RNA +namespace: biological_process +def: "A defense process that protects an organism from invading foreign RNA." [GO:dos] +is_a: GO:0099046 ! clearance of foreign intracellular nucleic acids + +[Term] +id: GO:0099048 +name: CRISPR-cas system +namespace: biological_process +def: "An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci." [PMID:23495939] +is_a: GO:0099046 ! clearance of foreign intracellular nucleic acids + +[Term] +id: GO:0099049 +name: clathrin coat assembly involved in endocytosis +namespace: biological_process +def: "The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation." [PMID:21779028] +is_a: GO:0048268 ! clathrin coat assembly +relationship: part_of GO:0072583 ! clathrin-dependent endocytosis + +[Term] +id: GO:0099050 +name: vesicle scission +namespace: biological_process +def: "The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane." [PMID:21779028] +is_a: GO:0090148 ! membrane fission + +[Term] +id: GO:0099051 +name: vesicle scission involved in endocytosis +namespace: biological_process +def: "The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane." [PMID:21779028] +is_a: GO:0099050 ! vesicle scission +intersection_of: GO:0099050 ! vesicle scission +intersection_of: part_of GO:0006897 ! endocytosis +relationship: part_of GO:0006897 ! endocytosis + +[Term] +id: GO:0099052 +name: vesicle scission involved in clathrin-mediated endocytosis +namespace: biological_process +def: "The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane." [PMID:21779028] +comment: Like other vesicle scission events this involves dynamin. At least some of the dynamin recruiting factors are distinct to scission of clathrin-coated vesicles (PMID:21779028). +is_a: GO:0099051 ! vesicle scission involved in endocytosis +intersection_of: GO:0099050 ! vesicle scission +intersection_of: part_of GO:0072583 ! clathrin-dependent endocytosis +relationship: part_of GO:0072583 ! clathrin-dependent endocytosis + +[Term] +id: GO:0099053 +name: activating signal cointegrator 1 complex +namespace: cellular_component +def: "A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3." [PMID:12077347] +synonym: "ASC-1 complex" EXACT [PMID:12077347] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex + +[Term] +id: GO:0099054 +name: presynapse assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494] +subset: goslim_synapse +synonym: "presynapse biogenesis" EXACT [GOC:mah] +synonym: "presynaptic terminal assembly" EXACT [PMID:24449494] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0099172 ! presynapse organization +relationship: part_of GO:0007416 ! synapse assembly + +[Term] +id: GO:0099055 +name: integral component of postsynaptic membrane +namespace: cellular_component +def: "The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098936 ! intrinsic component of postsynaptic membrane +is_a: GO:0099699 ! integral component of synaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane + +[Term] +id: GO:0099056 +name: integral component of presynaptic membrane +namespace: cellular_component +def: "The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +synonym: "integral component of presynaptic plasma membrane" EXACT [] +is_a: GO:0098889 ! intrinsic component of presynaptic membrane +is_a: GO:0099699 ! integral component of synaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0042734 ! presynaptic membrane + +[Term] +id: GO:0099057 +name: integral component of presynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098946 ! intrinsic component of presynaptic endocytic zone membrane +is_a: GO:0099056 ! integral component of presynaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098835 ! presynaptic endocytic zone membrane + +[Term] +id: GO:0099058 +name: integral component of postsynaptic endocytic zone membrane +namespace: cellular_component +def: "The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098947 ! intrinsic component of postsynaptic endocytic zone membrane +is_a: GO:0099055 ! integral component of postsynaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098844 ! postsynaptic endocytic zone membrane + +[Term] +id: GO:0099059 +name: integral component of presynaptic active zone membrane +namespace: cellular_component +def: "The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098945 ! intrinsic component of presynaptic active zone membrane +is_a: GO:0099056 ! integral component of presynaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0048787 ! presynaptic active zone membrane + +[Term] +id: GO:0099060 +name: integral component of postsynaptic specialization membrane +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098948 ! intrinsic component of postsynaptic specialization membrane +is_a: GO:0099055 ! integral component of postsynaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0099634 ! postsynaptic specialization membrane + +[Term] +id: GO:0099061 +name: integral component of postsynaptic density membrane +namespace: cellular_component +def: "The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099060 ! integral component of postsynaptic specialization membrane +is_a: GO:0099146 ! intrinsic component of postsynaptic density membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098839 ! postsynaptic density membrane + +[Term] +id: GO:0099062 +name: integral component of postsynaptic early endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098950 ! intrinsic component of postsynaptic early endosome membrane +is_a: GO:0099064 ! integral component of postsynaptic endosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098896 ! postsynaptic early endosome membrane + +[Term] +id: GO:0099063 +name: integral component of postsynaptic recycling endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098951 ! intrinsic component of postsynaptic recycling endosome membrane +is_a: GO:0099064 ! integral component of postsynaptic endosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098944 ! postsynaptic recycling endosome membrane + +[Term] +id: GO:0099064 +name: integral component of postsynaptic endosome membrane +namespace: cellular_component +def: "The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031303 ! integral component of endosome membrane +is_a: GO:0098949 ! intrinsic component of postsynaptic endosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098895 ! postsynaptic endosome membrane + +[Term] +id: GO:0099065 +name: integral component of spine apparatus membrane +namespace: cellular_component +def: "The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0098952 ! intrinsic component of spine apparatus membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098897 ! spine apparatus membrane + +[Term] +id: GO:0099066 +name: integral component of neuronal dense core vesicle membrane +namespace: cellular_component +def: "The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:0098675 ! intrinsic component of neuronal dense core vesicle membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0099012 ! neuronal dense core vesicle membrane + +[Term] +id: GO:0099067 +name: integral component of presynaptic endosome membrane +namespace: cellular_component +def: "The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0031303 ! integral component of endosome membrane +is_a: GO:0098955 ! intrinsic component of presynaptic endosome membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0098954 ! presynaptic endosome membrane + +[Term] +id: GO:0099068 +name: postsynapse assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL] +synonym: "postsynapse biogenesis" EXACT [GOC:mah] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0099173 ! postsynapse organization +relationship: part_of GO:0007416 ! synapse assembly + +[Term] +id: GO:0099069 +name: synaptic vesicle tethering involved in synaptic vesicle exocytosis +namespace: biological_process +def: "The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion." [GOC:rn] +is_a: GO:0090522 ! vesicle tethering involved in exocytosis +relationship: part_of GO:0016081 ! synaptic vesicle docking + +[Term] +id: GO:0099070 +name: static microtubule bundle +namespace: cellular_component +def: "A microtubule bundle that has a constant length, and in which microtubule sliding does not take place." [GOC:vw, PMID:26124291] +comment: In fission yeast, quiescent cells contain only static microtubule bundles. +synonym: "Q-MT bundle" NARROW [] +synonym: "quiescent cell microtubule bundle" NARROW [] +synonym: "quiescent cell MT bundle" NARROW [] +is_a: GO:0097427 ! microtubule bundle + +[Term] +id: GO:0099071 +name: dynamic microtubule bundle +namespace: cellular_component +def: "A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place." [GOC:vw, PMID:26124291] +is_a: GO:0097427 ! microtubule bundle + +[Term] +id: GO:0099072 +name: regulation of postsynaptic membrane neurotransmitter receptor levels +namespace: biological_process +def: "Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0065008 ! regulation of biological quality + +[Term] +id: GO:0099073 +name: mitochondrion-derived vesicle +namespace: cellular_component +def: "A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae." [GOC:bc, GOC:pad, GOC:PARL-UCL, PMID:18207745, PMID:20619655, PMID:22226745, PMID:23300790] +synonym: "MDV" EXACT [PMID:26618722] +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0099074 +name: mitochondrion to lysosome transport +namespace: biological_process +def: "Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles." [GOC:bc, GOC:pad, GOC:PARL-UCL, PMID:20619655] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0099075 ! mitochondrion-derived vesicle mediated transport + +[Term] +id: GO:0099075 +name: mitochondrion-derived vesicle mediated transport +namespace: biological_process +def: "Transport from the mitochondrion, mediated by mitochondrion derived vesicles." [GOC:bc, GOC:pad, GOC:PARL-UCL, PMID:2061965, PMID:20619655] +is_a: GO:0006839 ! mitochondrial transport +is_a: GO:0016192 ! vesicle-mediated transport + +[Term] +id: GO:0099076 +name: mitochondrion to peroxisome transport +namespace: biological_process +def: "Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles." [GOC:bc, GOC:pad, GOC:PARL-UCL, PMID:20619655] +is_a: GO:0099075 ! mitochondrion-derived vesicle mediated transport + +[Term] +id: GO:0099077 +name: histone-dependent DNA binding +namespace: molecular_function +def: "DNA-binding activity that is dependent on binding to a histone." [PMID:11691835] +is_a: GO:0003677 ! DNA binding + +[Term] +id: GO:0099078 +name: BORC complex +namespace: cellular_component +def: "A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors." [GOC:dos, GOC:li, PMID:25898167] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0099079 +name: actin body +namespace: cellular_component +def: "An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin." [PMID:16914523] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0015629 ! actin cytoskeleton + +[Term] +id: GO:0099080 +name: supramolecular complex +namespace: cellular_component +def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos] +is_a: GO:0110165 ! cellular anatomical entity + +[Term] +id: GO:0099081 +name: supramolecular polymer +namespace: cellular_component +def: "A polymeric supramolecular structure." [GOC:dos] +is_a: GO:0099080 ! supramolecular complex + +[Term] +id: GO:0099082 +name: retrograde trans-synaptic signaling by neuropeptide +namespace: biological_process +def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] +subset: goslim_synapse +is_a: GO:0098917 ! retrograde trans-synaptic signaling +is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide + +[Term] +id: GO:0099083 +name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission +namespace: biological_process +def: "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission + +[Term] +id: GO:0099084 +name: postsynaptic specialization organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane." [GOC:BHF, GOC:sjp, PMID:21525273, PMID:26834556] +subset: goslim_synapse +synonym: "post synaptic specialization organization" EXACT [] +synonym: "post-synaptic specialization organization" EXACT [] +synonym: "postsynaptic specialization organisation" EXACT [] +is_a: GO:0006996 ! organelle organization +relationship: part_of GO:0099173 ! postsynapse organization +created_by: pr +creation_date: 2011-07-27T05:17:12Z + +[Term] +id: GO:0099085 +name: DIF dechlorinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-." [PMID:1521542, PMID:22035794] +synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity" EXACT [] +synonym: "1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity" EXACT [] +synonym: "DIF-1 3(5)-dechlorinase activity" EXACT [] +synonym: "DIF-1 dechlorinase activity" EXACT [] +synonym: "differentiation-inducing factor 1 dechlorinase activity" EXACT [] +synonym: "differentiation-inducing factor dechlorinase activity" EXACT [] +is_a: GO:0016848 ! carbon-halide lyase activity + +[Term] +id: GO:0099086 +name: synaptonemal structure +namespace: cellular_component +def: "A proteinaceous scaffold found between homologous chromosomes during meiosis." [GOC:elh, GOC:vw] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0000794 ! condensed nuclear chromosome + +[Term] +id: GO:0099087 +name: anterograde axonal transport of messenger ribonucleoprotein complex +namespace: biological_process +def: "The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse." [GOC:dos, PMID:26586091] +subset: goslim_synapse +synonym: "anterograde axonal transport of mRNA RNP complex" EXACT [] +is_a: GO:0099088 ! axonal transport of messenger ribonucleoprotein complex +is_a: GO:0099641 ! anterograde axonal protein transport + +[Term] +id: GO:0099088 +name: axonal transport of messenger ribonucleoprotein complex +namespace: biological_process +def: "The directed movement of a messenger ribonucleoprotein complex along microtubules in axons." [GOC:dos, PMID:26586091] +subset: goslim_synapse +synonym: "axonal transport of mRNA RNP complex" EXACT [] +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0050658 ! RNA transport +is_a: GO:0098930 ! axonal transport +is_a: GO:0099640 ! axo-dendritic protein transport +relationship: occurs_in GO:1904115 ! axon cytoplasm + +[Term] +id: GO:0099089 +name: establishment of endoplasmic reticulum localization to postsynapse +namespace: biological_process +def: "The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine." [GOC:dos, PMID:21151132] +subset: goslim_synapse +synonym: "establishment of ER localization to postsynapse" EXACT [GOC:dos] +is_a: GO:0051686 ! establishment of ER localization + +[Term] +id: GO:0099091 +name: postsynaptic specialization, intracellular component +namespace: cellular_component +def: "A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components." [GOC:dos] +subset: goslim_synapse +is_a: GO:0043228 ! non-membrane-bounded organelle +intersection_of: GO:0043228 ! non-membrane-bounded organelle +intersection_of: part_of GO:0099572 ! postsynaptic specialization +relationship: part_of GO:0099572 ! postsynaptic specialization + +[Term] +id: GO:0099092 +name: postsynaptic density, intracellular component +namespace: cellular_component +def: "A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099091 ! postsynaptic specialization, intracellular component +intersection_of: GO:0043228 ! non-membrane-bounded organelle +intersection_of: part_of GO:0014069 ! postsynaptic density +relationship: part_of GO:0014069 ! postsynaptic density + +[Term] +id: GO:0099093 +name: calcium export from the mitochondrion +namespace: biological_process +def: "A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol." [GOC:dos, GOC:vw] +synonym: "calcium ion transmembrane export from mitochondrion" EXACT [] +synonym: "mitochondrial calcium ion export" BROAD [GOC:vw] +synonym: "mitochondrial calcium release" EXACT [] +is_a: GO:0006851 ! mitochondrial calcium ion transmembrane transport +is_a: GO:0051209 ! release of sequestered calcium ion into cytosol +is_a: GO:1901660 ! calcium ion export +is_a: GO:1990542 ! mitochondrial transmembrane transport + +[Term] +id: GO:0099094 +name: ligand-gated cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0015276 ! ligand-gated ion channel activity + +[Term] +id: GO:0099095 +name: ligand-gated anion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] +is_a: GO:0005253 ! anion channel activity +is_a: GO:0015276 ! ligand-gated ion channel activity + +[Term] +id: GO:0099096 +name: vestibular calyx terminal +namespace: cellular_component +def: "The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell." [PMID:10706428, PMID:25355208] +is_a: GO:0043679 ! axon terminus + +[Term] +id: GO:0099098 +name: microtubule polymerization based movement +namespace: biological_process +def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194] +is_a: GO:0007018 ! microtubule-based movement +intersection_of: GO:0007018 ! microtubule-based movement +intersection_of: has_part GO:0046785 ! microtubule polymerization +relationship: has_part GO:0046785 ! microtubule polymerization + +[Term] +id: GO:0099099 +name: G-protein gated ion channel activity +namespace: molecular_function +def: "An ion channel activity that is gated by binding of a G-protein beta-gamma dimer." [GOC:dos] +is_a: GO:0015075 ! ion transmembrane transporter activity +is_a: GO:0022836 ! gated channel activity + +[Term] +id: GO:0099100 +name: G-protein gated cation channel activity +namespace: molecular_function +def: "A cation channel activity that is gated by binding of a G-protein beta-gamma dimer." [GOC:dos] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0099099 ! G-protein gated ion channel activity + +[Term] +id: GO:0099101 +name: G-protein gated potassium channel activity +namespace: molecular_function +def: "A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer." [GOC:dos, PMID:9429760] +is_a: GO:0005267 ! potassium channel activity +is_a: GO:0099100 ! G-protein gated cation channel activity + +[Term] +id: GO:0099102 +name: G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential." [GOC:dos, PMID:9429760] +subset: goslim_synapse +is_a: GO:0099101 ! G-protein gated potassium channel activity +intersection_of: GO:0099101 ! G-protein gated potassium channel activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0099103 +name: channel activator activity +namespace: molecular_function +def: "Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel." [GOC:dos] +synonym: "channel gating activity" EXACT [] +is_a: GO:0016247 ! channel regulator activity + +[Term] +id: GO:0099104 +name: potassium channel activator activity +namespace: molecular_function +def: "Direct interaction with a potassium channel (binding or modification), resulting in its opening." [GOC:dos] +is_a: GO:0015459 ! potassium channel regulator activity +is_a: GO:0099103 ! channel activator activity + +[Term] +id: GO:0099105 +name: ion channel modulating, G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel." [GOC:dos] +synonym: "ion channel modulating, G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: has_part GO:0005216 ! ion channel activity +intersection_of: has_part GO:0099106 ! ion channel regulator activity +relationship: has_part GO:0005216 ! ion channel activity +relationship: has_part GO:0099106 ! ion channel regulator activity + +[Term] +id: GO:0099106 +name: ion channel regulator activity +namespace: molecular_function +def: "Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel." [GOC:dos] +is_a: GO:0016247 ! channel regulator activity +relationship: regulates GO:0015267 ! channel activity + +[Term] +id: GO:0099107 +name: ion channel regulator activity involved in G protein-coupled receptor signaling pathway +namespace: molecular_function +def: "Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling." [GOC:dos] +synonym: "ion channel regulator activity involved in G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0099106 ! ion channel regulator activity +intersection_of: GO:0099106 ! ion channel regulator activity +intersection_of: part_of GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: part_of GO:0007186 ! G protein-coupled receptor signaling pathway + +[Term] +id: GO:0099108 +name: potassium channel activator activity involved in G protein-coupled receptor signaling pathway +namespace: molecular_function +def: "Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling." [PMID:9429760] +comment: Examples include G-protein beta-gamma complexes that bind to and activate potassium channels. +subset: goslim_synapse +synonym: "potassium channel activator activity involved in G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0099104 ! potassium channel activator activity +is_a: GO:0099107 ! ion channel regulator activity involved in G protein-coupled receptor signaling pathway +intersection_of: GO:0099104 ! potassium channel activator activity +intersection_of: part_of GO:0007186 ! G protein-coupled receptor signaling pathway +relationship: part_of GO:0099109 ! potassium channel activating, G protein-coupled receptor signaling pathway + +[Term] +id: GO:0099109 +name: potassium channel activating, G protein-coupled receptor signaling pathway +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel." [GOC:dos, PMID:9429760] +synonym: "potassium channel activating, G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0099105 ! ion channel modulating, G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: has_part GO:0005267 ! potassium channel activity +intersection_of: has_part GO:0099104 ! potassium channel activator activity +relationship: has_part GO:0005267 ! potassium channel activity +relationship: has_part GO:0099104 ! potassium channel activator activity + +[Term] +id: GO:0099110 +name: microtubule polymerization based protein transport to cell tip cortex +namespace: biological_process +def: "The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached." [GOC:dos, GOC:vw, PMID:11018050] +is_a: GO:0099112 ! microtubule polymerization based protein transport +is_a: GO:1990896 ! protein localization to cell cortex of cell tip + +[Term] +id: GO:0099111 +name: microtubule-based transport +namespace: biological_process +def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] +is_a: GO:0006810 ! transport +is_a: GO:0007018 ! microtubule-based movement + +[Term] +id: GO:0099112 +name: microtubule polymerization based protein transport +namespace: biological_process +def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0099098 ! microtubule polymerization based movement +is_a: GO:0099118 ! microtubule-based protein transport + +[Term] +id: GO:0099113 +name: negative regulation of presynaptic cytosolic calcium concentration +namespace: biological_process +def: "Any process that decreases the concentration of calcium ions in the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0051481 ! negative regulation of cytosolic calcium ion concentration +is_a: GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +intersection_of: GO:0051481 ! negative regulation of cytosolic calcium ion concentration +intersection_of: occurs_in GO:0098793 ! presynapse + +[Term] +id: GO:0099115 +name: chromosome, subtelomeric region +namespace: cellular_component +def: "A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin." [GOC:mah, PMID:22771823, PMID:26205977] +synonym: "subtelomere" EXACT [] +xref: SO:0001997 +is_a: GO:0000781 ! chromosome, telomeric region +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19086 xsd:anyURI + +[Term] +id: GO:0099116 +name: tRNA 5'-end processing +namespace: biological_process +def: "The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA." [GOC:dos, GOC:pf, PMID:27484477] +synonym: "tRNA 5' processing" EXACT [] +is_a: GO:0008033 ! tRNA processing +is_a: GO:0034471 ! ncRNA 5'-end processing + +[Term] +id: GO:0099117 +name: protein transport along microtubule to cell tip +namespace: biological_process +def: "The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins." [PMID:15177031] +is_a: GO:0098840 ! protein transport along microtubule +is_a: GO:1990151 ! protein localization to cell tip +created_by: vw +creation_date: 2015-09-15T11:09:54Z + +[Term] +id: GO:0099118 +name: microtubule-based protein transport +namespace: biological_process +def: "A microtubule-based process that results in the transport of proteins." [GOC:vw] +is_a: GO:0015031 ! protein transport +is_a: GO:0099111 ! microtubule-based transport + +[Term] +id: GO:0099119 +name: 3-demethylubiquinol-8 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8." [GOC:ic] +is_a: GO:0061542 ! 3-demethylubiquinol-n 3-O-methyltransferase activity + +[Term] +id: GO:0099120 +name: socially cooperative development +namespace: biological_process +def: "Development a structure consisting of multiple co-operating unicellular organisms of the same species. Examples include sorocarp development in Dictystelia and co-operative colonial structures formed by Myxococcus xanthus for the purpose of predation and fruiting body formation." [PMID:12448714] +synonym: "colonial development" EXACT [] +synonym: "socially co-operative development" EXACT [] +is_a: GO:0048856 ! anatomical structure development +is_a: GO:0051703 ! intraspecies interaction between organisms + +[Term] +id: GO:0099121 +name: fungal sorus development +namespace: biological_process +def: "The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure." [GOC:dos] +is_a: GO:0048608 ! reproductive structure development + +[Term] +id: GO:0099122 +name: RNA polymerase II C-terminal domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function." [PMID:20889714] +synonym: "RNAP II C-terminal binding" EXACT [] +is_a: GO:0000993 ! RNA polymerase II complex binding + +[Term] +id: GO:0099123 +name: somato-dendritic dopamine secretion +namespace: biological_process +def: "The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron." [GOC:bf, GOC:PARL, PMID:21576241] +synonym: "somatodendritic dopamine release" EXACT [PMID:21576241] +synonym: "STD DA release" EXACT [PMID:21576241] +synonym: "STD dopamine release" EXACT [PMID:21576241] +is_a: GO:0014046 ! dopamine secretion +is_a: GO:0051649 ! establishment of localization in cell +intersection_of: GO:0014046 ! dopamine secretion +intersection_of: occurs_in GO:0036477 ! somatodendritic compartment +relationship: occurs_in GO:0036477 ! somatodendritic compartment + +[Term] +id: GO:0099124 +name: axonal dopamine secretion +namespace: biological_process +def: "The regulated release of dopamine from an axon." [GOC:bf, GOC:PARL, PMID:21576241] +synonym: "axonal DA release" EXACT [PMID:21576241] +synonym: "axonal dopamine release" EXACT [PMID:21576241] +is_a: GO:0014046 ! dopamine secretion +is_a: GO:0051649 ! establishment of localization in cell +intersection_of: GO:0014046 ! dopamine secretion +intersection_of: occurs_in GO:0030424 ! axon +relationship: occurs_in GO:0030424 ! axon + +[Term] +id: GO:0099125 +name: PAK family kinase-Sog2 complex +namespace: cellular_component +def: "A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network." [PMID:23462181] +is_a: GO:1902911 ! protein kinase complex + +[Term] +id: GO:0099126 +name: transforming growth factor beta complex +namespace: cellular_component +def: "A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP." [GOC:bhm, PMID:22943793] +synonym: "TGF-beta complex" EXACT [] +synonym: "TGF-beta dimer" EXACT [] +synonym: "TGFB complex" EXACT [] +synonym: "TGFB dimer" EXACT [] +synonym: "TGFbeta complex" EXACT [] +synonym: "TGFbeta dimer" EXACT [] +xref: IntAct:EBI-12501958 +xref: IntAct:EBI-12502251 +xref: IntAct:EBI-12502440 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0099127 +name: envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism." [PMID:19491403] +is_a: GO:0035738 ! envenomation resulting in modulation of process in other organism +relationship: has_part GO:1905753 ! positive regulation of argininosuccinate synthase activity + +[Term] +id: GO:0099128 +name: mitochondrial iron-sulfur cluster assembly complex +namespace: cellular_component +def: "A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine." [PMID:27519411] +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0099129 +name: cochlear outer hair cell electromotile response +namespace: biological_process +def: "A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification." [PMID:12239568, PMID:2187727] +is_a: GO:0006928 ! movement of cell or subcellular component + +[Term] +id: GO:0099130 +name: estrogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any estrogen." [GOC:dos] +is_a: GO:0042562 ! hormone binding + +[Term] +id: GO:0099134 +name: chimeric sorocarp development +namespace: biological_process +def: "Development of a sorocarp formed by aggregation of cells with different genotypes." [PMID:18272966] +subset: gocheck_do_not_manually_annotate +is_a: GO:0030587 ! sorocarp development +is_a: GO:0099136 ! chimeric non-reproductive fruiting body development + +[Term] +id: GO:0099135 +name: chimeric colonial development +namespace: biological_process +def: "Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype." [PMID:18272966] +subset: gocheck_do_not_manually_annotate +is_a: GO:0099120 ! socially cooperative development + +[Term] +id: GO:0099136 +name: chimeric non-reproductive fruiting body development +namespace: biological_process +def: "Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes." [PMID:18272966] +subset: gocheck_do_not_manually_annotate +is_a: GO:0090702 ! non-reproductive fruiting body development +is_a: GO:0099135 ! chimeric colonial development + +[Term] +id: GO:0099137 +name: altruistic, chimeric, non-reproductive fruiting body development +namespace: biological_process +def: "Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell." [PMID:18272966] +synonym: "fully co-operative, chimeric, non-reproductive fruiting body development" EXACT [] +is_a: GO:0099136 ! chimeric non-reproductive fruiting body development + +[Term] +id: GO:0099138 +name: altruistic, chimeric sorocarp development +namespace: biological_process +def: "Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell." [PMID:18272966] +synonym: "fully co-operative, chimeric sorocarp development" EXACT [] +is_a: GO:0099134 ! chimeric sorocarp development +is_a: GO:0099137 ! altruistic, chimeric, non-reproductive fruiting body development + +[Term] +id: GO:0099139 +name: cheating during chimeric sorocarp development +namespace: biological_process +def: "Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes." [PMID:18272966] +is_a: GO:1901261 ! regulation of sorocarp spore cell differentiation +relationship: part_of GO:0099134 ! chimeric sorocarp development + +[Term] +id: GO:0099140 +name: presynaptic actin cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0030036 ! actin cytoskeleton organization +is_a: GO:0099187 ! presynaptic cytoskeleton organization +created_by: dos +creation_date: 2017-06-09T18:34:19Z + +[Term] +id: GO:0099141 +name: cellular response to protozoan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan." [GOC:dos] +is_a: GO:0001562 ! response to protozoan + +[Term] +id: GO:0099142 +name: intracellularly ATP-gated ion channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane." [PMID:9755289] +is_a: GO:0005217 ! intracellular ligand-gated ion channel activity +is_a: GO:0035381 ! ATP-gated ion channel activity + +[Term] +id: GO:0099143 +name: presynaptic actin cytoskeleton +namespace: cellular_component +def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0015629 ! actin cytoskeleton +is_a: GO:0099569 ! presynaptic cytoskeleton +intersection_of: GO:0015629 ! actin cytoskeleton +intersection_of: part_of GO:0098793 ! presynapse +created_by: dos +creation_date: 2017-06-09T18:36:19Z + +[Term] +id: GO:0099144 +name: anchored component of synaptic membrane +namespace: cellular_component +def: "The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0046658 ! anchored component of plasma membrane +is_a: GO:0099240 ! intrinsic component of synaptic membrane +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0097060 ! synaptic membrane +created_by: dos +creation_date: 2017-05-25T17:25:19Z + +[Term] +id: GO:0099145 +name: regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0017157 ! regulation of exocytosis +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:1902683 ! regulation of receptor localization to synapse +is_a: GO:1904375 ! regulation of protein localization to cell periphery +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098967 ! exocytic insertion of neurotransmitter receptor to postsynaptic membrane +relationship: regulates GO:0098967 ! exocytic insertion of neurotransmitter receptor to postsynaptic membrane +created_by: dos +creation_date: 2017-06-09T18:49:26Z + +[Term] +id: GO:0099146 +name: intrinsic component of postsynaptic density membrane +namespace: cellular_component +def: "The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic specialization membrane" NARROW [] +is_a: GO:0098948 ! intrinsic component of postsynaptic specialization membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0098839 ! postsynaptic density membrane +relationship: part_of GO:0098839 ! postsynaptic density membrane +created_by: dos +creation_date: 2017-07-05T10:43:24Z + +[Term] +id: GO:0099147 +name: extrinsic component of postsynaptic density membrane +namespace: cellular_component +def: "The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:autophagy, GOC:mf] +subset: goslim_synapse +is_a: GO:0098892 ! extrinsic component of postsynaptic specialization membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0098839 ! postsynaptic density membrane +relationship: part_of GO:0098839 ! postsynaptic density membrane +created_by: dos +creation_date: 2017-07-05T10:44:43Z + +[Term] +id: GO:0099148 +name: regulation of synaptic vesicle docking +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle docking." [GOC:dos] +subset: goslim_synapse +is_a: GO:0106020 ! regulation of vesicle docking +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016081 ! synaptic vesicle docking +relationship: regulates GO:0016081 ! synaptic vesicle docking +created_by: dos +creation_date: 2017-07-05T13:10:10Z + +[Term] +id: GO:0099149 +name: regulation of postsynaptic neurotransmitter receptor internalization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse." [GOC:ai] +subset: goslim_synapse +synonym: "regulation of postsynaptic neurotransmitter receptor endocytosis" EXACT syngo_official_label [] +is_a: GO:0002090 ! regulation of receptor internalization +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098884 ! postsynaptic neurotransmitter receptor internalization +relationship: regulates GO:0098884 ! postsynaptic neurotransmitter receptor internalization +created_by: dos +creation_date: 2017-07-05T13:13:49Z + +[Term] +id: GO:0099150 +name: regulation of postsynaptic specialization assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization." [GOC:dos] +subset: goslim_synapse +is_a: GO:0150052 ! regulation of postsynapse assembly +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098698 ! postsynaptic specialization assembly +relationship: regulates GO:0098698 ! postsynaptic specialization assembly +created_by: dos +creation_date: 2017-07-05T13:20:48Z + +[Term] +id: GO:0099151 +name: regulation of postsynaptic density assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099150 ! regulation of postsynaptic specialization assembly +is_a: GO:1904889 ! regulation of excitatory synapse assembly +is_a: GO:1905874 ! regulation of postsynaptic density organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097107 ! postsynaptic density assembly +relationship: regulates GO:0097107 ! postsynaptic density assembly +created_by: dos +creation_date: 2017-07-05T13:20:48Z + +[Term] +id: GO:0099152 +name: regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles." [GOC:dos, PMID:20098723] +subset: goslim_synapse +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:1902683 ! regulation of receptor localization to synapse +is_a: GO:1905749 ! regulation of endosome to plasma membrane protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098887 ! neurotransmitter receptor transport, endosome to postsynaptic membrane +relationship: regulates GO:0098887 ! neurotransmitter receptor transport, endosome to postsynaptic membrane +created_by: dos +creation_date: 2017-08-25T15:01:11Z + +[Term] +id: GO:0099153 +name: synaptic transmission, serotonergic +namespace: biological_process +def: "The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, GOC:dph] +synonym: "serotonergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission +created_by: dos +creation_date: 2017-07-05T14:16:51Z + +[Term] +id: GO:0099154 +name: serotonergic synapse +namespace: cellular_component +def: "A synapse that uses serotonin as a neurotransmitter." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-07-05T14:22:05Z + +[Term] +id: GO:0099155 +name: synaptic transmission, noradrenergic +namespace: biological_process +def: "The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, GOC:dph] +synonym: "noradrenergic synaptic transmission" EXACT [] +is_a: GO:0007268 ! chemical synaptic transmission +created_by: dos +creation_date: 2017-07-05T14:36:55Z + +[Term] +id: GO:0099156 +name: cell-cell signaling via exosome +namespace: biological_process +def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038] +synonym: "exosome mediated" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +created_by: dos +creation_date: 2017-07-05T16:40:45Z + +[Term] +id: GO:0099157 +name: trans-synaptic signalling via exosome +namespace: biological_process +def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038] +subset: goslim_synapse +synonym: "exosome mediated transynaptic signalling" EXACT [] +is_a: GO:0099156 ! cell-cell signaling via exosome +is_a: GO:0099537 ! trans-synaptic signaling +created_by: dos +creation_date: 2017-07-05T16:49:44Z + +[Term] +id: GO:0099158 +name: regulation of recycling endosome localization within postsynapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse." [GOC:dos, PMID:20098723] +subset: goslim_synapse +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:1903421 ! regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036466 ! synaptic vesicle recycling via endosome +relationship: regulates GO:0036466 ! synaptic vesicle recycling via endosome +created_by: dos +creation_date: 2017-08-25T15:37:50Z + +[Term] +id: GO:0099159 +name: regulation of modification of postsynaptic structure +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of modification of postsynaptic structure." [GOC:dos] +subset: goslim_synapse +synonym: "regulation of postsynapse remodelling" EXACT [] +is_a: GO:1905244 ! regulation of modification of synaptic structure +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099010 ! modification of postsynaptic structure +relationship: regulates GO:0099010 ! modification of postsynaptic structure +created_by: dos +creation_date: 2017-08-25T15:47:55Z + +[Term] +id: GO:0099160 +name: postsynaptic intermediate filament cytoskeleton +namespace: cellular_component +def: "The intermediate filament cytoskeleton that is part of a postsynapse." [GOC:dos, PMID:25869803] +subset: goslim_synapse +is_a: GO:0045111 ! intermediate filament cytoskeleton +is_a: GO:0099571 ! postsynaptic cytoskeleton +intersection_of: GO:0045111 ! intermediate filament cytoskeleton +intersection_of: part_of GO:0098794 ! postsynapse +created_by: dos +creation_date: 2017-08-28T15:26:08Z + +[Term] +id: GO:0099161 +name: regulation of presynaptic dense core granule exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis." [GOC:dos, PMID:17881523] +subset: goslim_synapse +synonym: "regulation of presynaptic dense core vesicle exocytosis" EXACT syngo_official_label [] +is_a: GO:1903233 ! regulation of calcium ion-dependent exocytosis of neurotransmitter +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099525 ! presynaptic dense core vesicle exocytosis +relationship: regulates GO:0099525 ! presynaptic dense core vesicle exocytosis +created_by: dos +creation_date: 2017-09-10T10:59:08Z + +[Term] +id: GO:0099162 +name: regulation of neurotransmitter loading into synaptic vesicle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles." [GOC:dos, PMID:25176177] +subset: goslim_synapse +synonym: "regulation of neurotransmitter uptake into synaptic vesicle" EXACT [PMID:15217342] +synonym: "regulation of synaptic vesicle neurotransmitter loading" EXACT syngo_official_label [] +is_a: GO:0051588 ! regulation of neurotransmitter transport +is_a: GO:0098693 ! regulation of synaptic vesicle cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098700 ! neurotransmitter loading into synaptic vesicle +relationship: regulates GO:0098700 ! neurotransmitter loading into synaptic vesicle +created_by: dos +creation_date: 2017-09-10T11:07:57Z + +[Term] +id: GO:0099163 +name: synaptic signaling by nitric oxide +namespace: biological_process +def: "Cell-cell signaling to or from a synapse, mediated by nitric oxide." [GOC:dos, PMID:19038221] +subset: goslim_synapse +is_a: GO:0099536 ! synaptic signaling + +[Term] +id: GO:0099164 +name: postsynaptic specialization membrane of symmetric synapse +namespace: cellular_component +def: "The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099634 ! postsynaptic specialization membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane +intersection_of: part_of GO:0099629 ! postsynaptic specialization of symmetric synapse +relationship: part_of GO:0099629 ! postsynaptic specialization of symmetric synapse +created_by: dos +creation_date: 2017-09-10T11:50:44Z + +[Term] +id: GO:0099165 +name: postsynaptic specialization of symmetric synapse, intracellular component +namespace: cellular_component +def: "A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099091 ! postsynaptic specialization, intracellular component +intersection_of: GO:0043228 ! non-membrane-bounded organelle +intersection_of: part_of GO:0099629 ! postsynaptic specialization of symmetric synapse +relationship: part_of GO:0099629 ! postsynaptic specialization of symmetric synapse +created_by: dos +creation_date: 2017-09-10T11:54:15Z + +[Term] +id: GO:0099166 +name: intrinsic component of postsynaptic specialization membrane of symmetric synapse +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos] +subset: goslim_synapse +synonym: "intrinsic to postsynaptic specialization membrane of symmetric synapse" NARROW [] +is_a: GO:0098948 ! intrinsic component of postsynaptic specialization membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +relationship: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +created_by: dos +creation_date: 2017-09-10T11:56:47Z + +[Term] +id: GO:0099167 +name: integral component of postsynaptic specialization membrane of symmetric synapse +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099060 ! integral component of postsynaptic specialization membrane +is_a: GO:0099166 ! intrinsic component of postsynaptic specialization membrane of symmetric synapse +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +created_by: dos +creation_date: 2017-09-10T11:58:46Z + +[Term] +id: GO:0099168 +name: extrinsic component of postsynaptic specialization membrane of symmetric synapse +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098892 ! extrinsic component of postsynaptic specialization membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +relationship: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +created_by: dos +creation_date: 2017-09-10T12:00:26Z + +[Term] +id: GO:0099169 +name: anchored component of postsynaptic specialization membrane of symmetric synapse +namespace: cellular_component +def: "The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099030 ! anchored component of postsynaptic specialization membrane +is_a: GO:0099166 ! intrinsic component of postsynaptic specialization membrane of symmetric synapse +intersection_of: GO:0031225 ! anchored component of membrane +intersection_of: part_of GO:0099164 ! postsynaptic specialization membrane of symmetric synapse +created_by: dos +creation_date: 2017-09-10T12:01:53Z + +[Term] +id: GO:0099170 +name: postsynaptic modulation of chemical synaptic transmission +namespace: biological_process +def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos] +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse +created_by: dos +creation_date: 2017-09-11T17:09:17Z + +[Term] +id: GO:0099171 +name: presynaptic modulation of chemical synaptic transmission +namespace: biological_process +def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos] +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: occurs_in GO:0098793 ! presynapse +relationship: occurs_in GO:0098793 ! presynapse +created_by: dos +creation_date: 2017-09-11T17:09:31Z + +[Term] +id: GO:0099172 +name: presynapse organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos] +subset: goslim_synapse +synonym: "presynapse development" EXACT [] +synonym: "presynapse morphogenesis" RELATED [GOC:BHF] +synonym: "presynapse organisation" EXACT [] +synonym: "presynapse organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0050808 ! synapse organization + +[Term] +id: GO:0099173 +name: postsynapse organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos] +subset: goslim_synapse +synonym: "postsynapse development" EXACT [] +synonym: "postsynapse morphogenesis" RELATED [GOC:BHF] +synonym: "postsynapse organisation" EXACT [] +synonym: "postsynapse organization and biogenesis" RELATED [GOC:mah] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0050808 ! synapse organization + +[Term] +id: GO:0099174 +name: regulation of presynapse organization +namespace: biological_process +def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_synapse +synonym: "regulation of presynapse organisation" EXACT [GOC:mah] +synonym: "regulation of presynapse organization and biogenesis" RELATED [GOC:mah] +synonym: "regulation of presynapse structure" EXACT [] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099172 ! presynapse organization +relationship: regulates GO:0099172 ! presynapse organization + +[Term] +id: GO:0099175 +name: regulation of postsynapse organization +namespace: biological_process +def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb] +subset: goslim_synapse +synonym: "regulation of postsynapse organisation" EXACT [GOC:mah] +synonym: "regulation of postsynapse organization and biogenesis" RELATED [GOC:mah] +synonym: "regulation of postsynapse structure" EXACT [] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099173 ! postsynapse organization +relationship: regulates GO:0099173 ! postsynapse organization + +[Term] +id: GO:0099176 +name: regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex." [GOC:dos, PMID:23209303] +subset: goslim_synapse +synonym: "regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +is_a: GO:0099177 ! regulation of trans-synaptic signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098942 ! retrograde trans-synaptic signaling by trans-synaptic protein complex +relationship: regulates GO:0098942 ! retrograde trans-synaptic signaling by trans-synaptic protein complex + +[Term] +id: GO:0099177 +name: regulation of trans-synaptic signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099537 ! trans-synaptic signaling +relationship: regulates GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0099178 +name: regulation of retrograde trans-synaptic signaling by endocanabinoid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid." [GOC:dos, PMID:15664177] +synonym: "regulation of endocannabinoid-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +is_a: GO:0099177 ! regulation of trans-synaptic signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid +relationship: regulates GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid + +[Term] +id: GO:0099179 +name: regulation of synaptic membrane adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes." [GOC:dos] +subset: goslim_synapse +synonym: "regulation of synapse adhesion between pre- and post-synapse" EXACT syngo_official_label [] +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099560 ! synaptic membrane adhesion +relationship: regulates GO:0099560 ! synaptic membrane adhesion + +[Term] +id: GO:0099180 +name: zinc ion import into synaptic vesicle +namespace: biological_process +def: "The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle." [PMID:9990090] +subset: goslim_synapse +synonym: "zinc import into synaptic vesicle" EXACT [] +synonym: "Zn2+ import into synaptic vesicle" EXACT [] +is_a: GO:0062111 ! zinc ion import into organelle + +[Term] +id: GO:0099181 +name: structural constituent of presynapse +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a presynapse." [GOC:dos, PMID:23751498] +subset: goslim_synapse +is_a: GO:0098918 ! structural constituent of synapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: part_of GO:0099172 ! presynapse organization +relationship: occurs_in GO:0098793 ! presynapse +relationship: part_of GO:0099172 ! presynapse organization +created_by: dos +creation_date: 2017-12-20T13:42:46Z + +[Term] +id: GO:0099182 +name: presynaptic intermediate filament cytoskeleton +namespace: cellular_component +def: "The intermediate filament cytoskeleton that is part of a presynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045111 ! intermediate filament cytoskeleton +is_a: GO:0099569 ! presynaptic cytoskeleton +intersection_of: GO:0045111 ! intermediate filament cytoskeleton +intersection_of: part_of GO:0098793 ! presynapse +created_by: dos +creation_date: 2017-12-01T18:10:21Z + +[Term] +id: GO:0099183 +name: trans-synaptic signaling by BDNF, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099191 ! trans-synaptic signaling by BDNF +is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission +created_by: dos +creation_date: 2017-12-01T18:25:24Z + +[Term] +id: GO:0099184 +name: structural constituent of postsynaptic intermediate filament cytoskeleton +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005200 ! structural constituent of cytoskeleton +is_a: GO:0099186 ! structural constituent of postsynapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0099160 ! postsynaptic intermediate filament cytoskeleton +intersection_of: part_of GO:0099185 ! postsynaptic intermediate filament cytoskeleton organization +relationship: occurs_in GO:0099160 ! postsynaptic intermediate filament cytoskeleton +relationship: part_of GO:0099185 ! postsynaptic intermediate filament cytoskeleton organization +created_by: dos +creation_date: 2017-12-20T13:45:35Z + +[Term] +id: GO:0099185 +name: postsynaptic intermediate filament cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0045104 ! intermediate filament cytoskeleton organization +is_a: GO:0099188 ! postsynaptic cytoskeleton organization +created_by: dos +creation_date: 2017-12-20T13:47:30Z + +[Term] +id: GO:0099186 +name: structural constituent of postsynapse +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of a postsynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098918 ! structural constituent of synapse +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0098794 ! postsynapse +intersection_of: part_of GO:0099173 ! postsynapse organization +relationship: occurs_in GO:0098794 ! postsynapse +relationship: part_of GO:0099173 ! postsynapse organization +created_by: dos +creation_date: 2017-12-20T14:54:33Z + +[Term] +id: GO:0099187 +name: presynaptic cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos] +is_a: GO:0007010 ! cytoskeleton organization +relationship: part_of GO:0099172 ! presynapse organization +created_by: dos +creation_date: 2017-12-20T15:05:34Z + +[Term] +id: GO:0099188 +name: postsynaptic cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] +subset: goslim_synapse +is_a: GO:0007010 ! cytoskeleton organization +relationship: part_of GO:0099173 ! postsynapse organization +created_by: dos +creation_date: 2017-12-20T15:06:57Z + +[Term] +id: GO:0099189 +name: postsynaptic spectrin-associated cytoskeleton +namespace: cellular_component +def: "The portion of the spectrin-associated cytoskeleton contained within the postsynapse." [GOC:dos, PMID:28576936] +subset: goslim_synapse +is_a: GO:0014731 ! spectrin-associated cytoskeleton +is_a: GO:0099571 ! postsynaptic cytoskeleton +intersection_of: GO:0014731 ! spectrin-associated cytoskeleton +intersection_of: part_of GO:0098794 ! postsynapse +created_by: dos +creation_date: 2017-12-20T15:29:09Z + +[Term] +id: GO:0099190 +name: postsynaptic spectrin-associated cytoskeleton organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse." [GOC:dos, PMID:28576936] +subset: goslim_synapse +is_a: GO:0099188 ! postsynaptic cytoskeleton organization +created_by: dos +creation_date: 2017-12-20T15:34:26Z + +[Term] +id: GO:0099191 +name: trans-synaptic signaling by BDNF +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft." [GOC:dos] +subset: goslim_synapse +synonym: "trans-synaptic signaling by brain-derived neurotrophic factor" EXACT [] +is_a: GO:0099537 ! trans-synaptic signaling +created_by: dos +creation_date: 2017-12-20T15:48:33Z + +[Term] +id: GO:0099192 +name: cerebellar Golgi cell to granule cell synapse +namespace: cellular_component +def: "A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell." [PMID:26134650] +subset: goslim_synapse +is_a: GO:0045202 ! synapse +created_by: dos +creation_date: 2017-12-20T16:12:25Z + +[Term] +id: GO:0099240 +name: intrinsic component of synaptic membrane +namespace: cellular_component +def: "The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:dos, GOC:mah] +subset: goslim_synapse +synonym: "intrinsic to synaptic membrane" NARROW [] +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0097060 ! synaptic membrane +relationship: part_of GO:0097060 ! synaptic membrane +created_by: dos +creation_date: 2017-05-25T17:23:21Z + +[Term] +id: GO:0099243 +name: extrinsic component of synaptic membrane +namespace: cellular_component +def: "The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +subset: goslim_synapse +is_a: GO:0019897 ! extrinsic component of plasma membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0097060 ! synaptic membrane +relationship: part_of GO:0097060 ! synaptic membrane +created_by: dos +creation_date: 2017-05-25T17:24:23Z + +[Term] +id: GO:0099400 +name: caveola neck +namespace: cellular_component +def: "A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it." [GOC:pad, GOC:PARL, PMID:17227843] +is_a: GO:0098590 ! plasma membrane region +is_a: GO:0098857 ! membrane microdomain +relationship: part_of GO:0005901 ! caveola + +[Term] +id: GO:0099401 +name: caveola bulb +namespace: cellular_component +def: "The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins." [GOC:PARL, GOC:POD, PMID:17227843] +synonym: "caveola crater" EXACT [] +is_a: GO:0098857 ! membrane microdomain + +[Term] +id: GO:0099402 +name: plant organ development +namespace: biological_process +def: "Development of a plant organ, a multi-tissue plant structure that forms a functional unit." [GOC:dos] +synonym: "development of a plant organ" EXACT [] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0048731 ! system development + +[Term] +id: GO:0099403 +name: maintenance of mitotic sister chromatid cohesion, telomeric +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle." [GOC:BHF, GOC:BHF_telomere, GOC:dos, GOC:rph, PMID:26373281] +synonym: "maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:mah] +synonym: "maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:mah] +synonym: "maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:mah] +is_a: GO:0034088 ! maintenance of mitotic sister chromatid cohesion +relationship: part_of GO:0099404 ! mitotic sister chromatid cohesion, telomeric + +[Term] +id: GO:0099404 +name: mitotic sister chromatid cohesion, telomeric +namespace: biological_process +def: "The cell cycle process in which telomeres of sister chromatids are joined during mitosis." [GOC:BHF, GOC:BHF_telomere, GOC:mah, GOC:rph, PMID:26373281] +synonym: "mitotic sister chromatid cohesion at telomere" EXACT [GOC:mah] +synonym: "sister chromatid cohesion at telomere at mitosis" EXACT [GOC:mah] +synonym: "telomeric mitotic sister chromatin cohesion" EXACT [GOC:mah] +is_a: GO:0007064 ! mitotic sister chromatid cohesion + +[Term] +id: GO:0099500 +name: vesicle fusion to plasma membrane +namespace: biological_process +def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] +is_a: GO:0006906 ! vesicle fusion +is_a: GO:0140029 ! exocytic process + +[Term] +id: GO:0099501 +name: exocytic vesicle membrane +namespace: cellular_component +def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos] +synonym: "secretory vesicle membrane" BROAD [] +is_a: GO:0030658 ! transport vesicle membrane + +[Term] +id: GO:0099502 +name: calcium-dependent activation of synaptic vesicle fusion +namespace: biological_process +def: "The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane." [PMID:23060190] +subset: goslim_synapse +is_a: GO:0031632 ! positive regulation of synaptic vesicle fusion to presynaptic active zone membrane +is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission +relationship: part_of GO:0016079 ! synaptic vesicle exocytosis + +[Term] +id: GO:0099503 +name: secretory vesicle +namespace: cellular_component +def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos] +subset: goslim_drosophila +is_a: GO:0031410 ! cytoplasmic vesicle + +[Term] +id: GO:0099504 +name: synaptic vesicle cycle +namespace: biological_process +def: "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters." [GOC:aruk, GOC:bc, PMID:15217342] +subset: goslim_synapse +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099003 ! vesicle-mediated transport in synapse +relationship: occurs_in GO:0098793 ! presynapse + +[Term] +id: GO:0099505 +name: regulation of presynaptic membrane potential +namespace: biological_process +def: "Any process that modulates the potential difference across a presynaptic membrane." [GOC:dph, GOC:ef] +subset: goslim_synapse +synonym: "regulation of pre-synaptic membrane potential" EXACT [] +is_a: GO:0042391 ! regulation of membrane potential + +[Term] +id: GO:0099506 +name: synaptic vesicle transport along actin filament +namespace: biological_process +def: "The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0030050 ! vesicle transport along actin filament +is_a: GO:0099514 ! synaptic vesicle cytoskeletal transport + +[Term] +id: GO:0099507 +name: ligand-gated ion channel activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos, PMID:15145529, PMID:19558451] +subset: goslim_synapse +synonym: "ligand gated ion channel activity involved in regulation of presynaptic membrane potential" EXACT [] +synonym: "ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential" EXACT [] +synonym: "ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential" EXACT [] +synonym: "ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential" EXACT [] +is_a: GO:0015276 ! ligand-gated ion channel activity +intersection_of: GO:0015276 ! ligand-gated ion channel activity +intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential +relationship: occurs_in GO:0042734 ! presynaptic membrane +relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential + +[Term] +id: GO:0099508 +name: voltage-gated ion channel activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse." [GOC:dos] +subset: goslim_synapse +synonym: "voltage gated ion channel activity involved in regulation of presynaptic membrane potential" EXACT [] +synonym: "voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential" EXACT [] +synonym: "voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential" EXACT [] +synonym: "voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential" EXACT [] +is_a: GO:0005244 ! voltage-gated ion channel activity +intersection_of: GO:0005244 ! voltage-gated ion channel activity +intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential +relationship: occurs_in GO:0042734 ! presynaptic membrane +relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential + +[Term] +id: GO:0099509 +name: regulation of presynaptic cytosolic calcium ion concentration +namespace: biological_process +def: "Any process that regulates the concentration of calcium in the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +synonym: "regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0051480 ! regulation of cytosolic calcium ion concentration +is_a: GO:0070050 ! neuron cellular homeostasis +intersection_of: GO:0051480 ! regulation of cytosolic calcium ion concentration +intersection_of: occurs_in GO:0098793 ! presynapse +relationship: occurs_in GO:0098793 ! presynapse + +[Term] +id: GO:0099510 +name: calcium ion binding involved in regulation of cytosolic calcium ion concentration +namespace: molecular_function +def: "The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations." [PMID:24442513, PMID:26190970] +synonym: "regulation of cytosolic calcium ion concentration by calcium ion buffering" EXACT [] +is_a: GO:0005509 ! calcium ion binding +intersection_of: GO:0005509 ! calcium ion binding +intersection_of: part_of GO:0051480 ! regulation of cytosolic calcium ion concentration +relationship: occurs_in GO:0005829 ! cytosol +relationship: part_of GO:0051480 ! regulation of cytosolic calcium ion concentration + +[Term] +id: GO:0099511 +name: voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels +namespace: molecular_function +def: "Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0051480 ! regulation of cytosolic calcium ion concentration +relationship: part_of GO:0051480 ! regulation of cytosolic calcium ion concentration + +[Term] +id: GO:0099512 +name: supramolecular fiber +namespace: cellular_component +alt_id: GO:0043205 +def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos] +synonym: "fibril" RELATED [] +is_a: GO:0099081 ! supramolecular polymer + +[Term] +id: GO:0099513 +name: polymeric cytoskeletal fiber +namespace: cellular_component +def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos] +is_a: GO:0099512 ! supramolecular fiber +relationship: part_of GO:0005856 ! cytoskeleton + +[Term] +id: GO:0099514 +name: synaptic vesicle cytoskeletal transport +namespace: biological_process +def: "The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0048489 ! synaptic vesicle transport +is_a: GO:0099518 ! vesicle cytoskeletal trafficking + +[Term] +id: GO:0099515 +name: actin filament-based transport +namespace: biological_process +def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb] +is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport +created_by: tb +creation_date: 2009-05-27T10:56:08Z + +[Term] +id: GO:0099517 +name: synaptic vesicle transport along microtubule +namespace: biological_process +def: "The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0047496 ! vesicle transport along microtubule +is_a: GO:0099514 ! synaptic vesicle cytoskeletal transport + +[Term] +id: GO:0099518 +name: vesicle cytoskeletal trafficking +namespace: biological_process +def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl] +synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl] +synonym: "vesicle cytoskeletal transport" EXACT [] +is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport +is_a: GO:0051650 ! establishment of vesicle localization + +[Term] +id: GO:0099519 +name: dense core granule cytoskeletal transport +namespace: biological_process +def: "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments." [GOC:kmv, PMID:23358451] +synonym: "dense core granule cytoskeletal transport" EXACT [] +synonym: "dense core vesicle cytoskeletal trafficking" EXACT [] +is_a: GO:0099518 ! vesicle cytoskeletal trafficking +is_a: GO:1901950 ! dense core granule transport +relationship: occurs_in GO:0030424 ! axon + +[Term] +id: GO:0099520 +name: ion antiporter activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos] +subset: goslim_synapse +synonym: "ion antiporter activity involved in regulation of pre-synaptic membrane potential" EXACT [] +is_a: GO:0015297 ! antiporter activity +relationship: occurs_in GO:0042734 ! presynaptic membrane + +[Term] +id: GO:0099521 +name: ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential." [GOC:dos, PMID:17220883] +subset: goslim_synapse +synonym: "ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential" EXACT [] +synonym: "ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential" EXACT [] +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +intersection_of: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential +relationship: occurs_in GO:0042734 ! presynaptic membrane +relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential + +[Term] +id: GO:0099522 +name: region of cytosol +namespace: cellular_component +def: "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol." [GOC:dos] +is_a: GO:0005829 ! cytosol +intersection_of: GO:0005829 ! cytosol +intersection_of: part_of GO:0005829 ! cytosol +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0099523 +name: presynaptic cytosol +namespace: cellular_component +def: "The region of the cytosol consisting of all cytosol that is part of the presynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099522 ! region of cytosol +intersection_of: GO:0005829 ! cytosol +intersection_of: part_of GO:0005829 ! cytosol +intersection_of: part_of GO:0098793 ! presynapse +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0099524 +name: postsynaptic cytosol +namespace: cellular_component +def: "The region of the cytosol consisting of all cytosol that is part of the postsynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099522 ! region of cytosol +intersection_of: GO:0005829 ! cytosol +intersection_of: part_of GO:0005829 ! cytosol +intersection_of: part_of GO:0098794 ! postsynapse +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0099525 +name: presynaptic dense core vesicle exocytosis +namespace: biological_process +def: "The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels." [PMID:17553987, PMID:24653208] +subset: goslim_synapse +is_a: GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +is_a: GO:0099011 ! neuronal dense core vesicle exocytosis + +[Term] +id: GO:0099526 +name: presynapse to nucleus signaling pathway +namespace: biological_process +def: "A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications)." [GOC:dos, PMID:24317321, PMID:25652077] +comment: This class does not cover the cellular machinery (motor proteins, cargo-recognition proteins) that transports the signaling protein along the cytoskeleton towards the nucleus. For these cases, annotate to the appropriate transport/trafficking term. +subset: goslim_synapse +synonym: "presynaptic signaling to nucleus" EXACT [] +is_a: GO:0098928 ! presynaptic signal transduction + +[Term] +id: GO:0099527 +name: postsynapse to nucleus signaling pathway +namespace: biological_process +def: "A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications)." [GOC:dos, PMID:24317321, PMID:25652077] +subset: goslim_synapse +synonym: "postsynaptic signaling to nucleus" EXACT [] +is_a: GO:0098926 ! postsynaptic signal transduction + +[Term] +id: GO:0099528 +name: G protein-coupled neurotransmitter receptor activity +namespace: molecular_function +def: "Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, GOC:fj, GOC:mah] +synonym: "G-protein coupled neurotransmitter receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +is_a: GO:0030594 ! neurotransmitter receptor activity + +[Term] +id: GO:0099529 +name: neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel)." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098960 ! postsynaptic neurotransmitter receptor activity +intersection_of: GO:0030594 ! neurotransmitter receptor activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0099530 +name: G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane." [GOC:dos] +subset: goslim_synapse +synonym: "G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +intersection_of: GO:0004930 ! G protein-coupled receptor activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +relationship: occurs_in GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0099531 +name: presynaptic process involved in chemical synaptic transmission +namespace: biological_process +def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] +subset: gocheck_do_not_annotate +subset: goslim_synapse +is_a: GO:0050877 ! nervous system process +intersection_of: GO:0050877 ! nervous system process +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: part_of GO:0007268 ! chemical synaptic transmission +relationship: occurs_in GO:0098793 ! presynapse +relationship: part_of GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099532 +name: synaptic vesicle endosomal processing +namespace: biological_process +def: "The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles." [GOC:aruk, GOC:bc, GOC:dos] +comment: This covers processing of synaptic vesicles trafficked to synapse as well as of endocytosed vesicles as part of recycling. It is there for not part of the synaptic vesicle cycle. +subset: goslim_synapse +synonym: "synaptic vesicle processing via endosome" EXACT [] +is_a: GO:0016197 ! endosomal transport + +[Term] +id: GO:0099533 +name: positive regulation of presynaptic cytosolic calcium concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +is_a: GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +intersection_of: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +intersection_of: occurs_in GO:0098793 ! presynapse + +[Term] +id: GO:0099534 +name: calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations." [PMID:24442513, PMID:26190970] +subset: goslim_synapse +synonym: "calcium ion binding involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "presynaptic calcium ion buffering" EXACT [] +synonym: "regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering" EXACT [] +is_a: GO:0099510 ! calcium ion binding involved in regulation of cytosolic calcium ion concentration +intersection_of: GO:0005509 ! calcium ion binding +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: occurs_in GO:0099523 ! presynaptic cytosol +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099535 +name: synapse-associated extracellular matrix +namespace: cellular_component +def: "The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft." [GOC:dos] +subset: goslim_synapse +synonym: "extra-synaptic extracellular matrix" EXACT [] +is_a: GO:0062023 ! collagen-containing extracellular matrix + +[Term] +id: GO:0099536 +name: synaptic signaling +namespace: biological_process +def: "Cell-cell signaling to, from or within a synapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0007267 ! cell-cell signaling +intersection_of: GO:0007267 ! cell-cell signaling +intersection_of: occurs_in GO:0045202 ! synapse +relationship: occurs_in GO:0045202 ! synapse +property_value: RO:0002161 NCBITaxon:4895 + +[Term] +id: GO:0099537 +name: trans-synaptic signaling +namespace: biological_process +def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099536 ! synaptic signaling + +[Term] +id: GO:0099538 +name: synaptic signaling via neuropeptide +namespace: biological_process +def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099536 ! synaptic signaling + +[Term] +id: GO:0099539 +name: neuropeptide secretion from presynapse +namespace: biological_process +def: "The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration." [PMID:17553987, PMID:24653208] +subset: goslim_synapse +synonym: "neuropeptide secretion from presynapse via dense core granule exocytosis" EXACT [] +is_a: GO:0002790 ! peptide secretion +is_a: GO:0099525 ! presynaptic dense core vesicle exocytosis +relationship: part_of GO:0099538 ! synaptic signaling via neuropeptide + +[Term] +id: GO:0099540 +name: trans-synaptic signaling by neuropeptide +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099537 ! trans-synaptic signaling +is_a: GO:0099538 ! synaptic signaling via neuropeptide + +[Term] +id: GO:0099541 +name: trans-synaptic signaling by lipid +namespace: biological_process +def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0099542 +name: trans-synaptic signaling by endocannabinoid +namespace: biological_process +def: "Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099541 ! trans-synaptic signaling by lipid + +[Term] +id: GO:0099543 +name: trans-synaptic signaling by soluble gas +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0099544 +name: perisynaptic space +namespace: cellular_component +def: "The extracellular region immediately adjacent to to a synapse." [GOC:dos] +subset: goslim_synapse +synonym: "extrasynaptic space" EXACT syngo_official_label [] +is_a: GO:0005576 ! extracellular region + +[Term] +id: GO:0099545 +name: trans-synaptic signaling by trans-synaptic complex +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099537 ! trans-synaptic signaling + +[Term] +id: GO:0099546 +name: protein catabolic process, modulating synaptic transmission +namespace: biological_process +def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0140246 ! protein catabolic process at synapse + +[Term] +id: GO:0099547 +name: regulation of translation at synapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0140243 ! regulation of translation at synapse +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0045202 ! synapse +intersection_of: regulates GO:0006412 ! translation +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099548 +name: trans-synaptic signaling by nitric oxide +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099163 ! synaptic signaling by nitric oxide +is_a: GO:0099543 ! trans-synaptic signaling by soluble gas + +[Term] +id: GO:0099549 +name: trans-synaptic signaling by carbon monoxide +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099543 ! trans-synaptic signaling by soluble gas + +[Term] +id: GO:0099550 +name: trans-synaptic signaling, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0099537 ! trans-synaptic signaling +intersection_of: GO:0099537 ! trans-synaptic signaling +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099551 +name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide +is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission + +[Term] +id: GO:0099552 +name: trans-synaptic signaling by lipid, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099541 ! trans-synaptic signaling by lipid +is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission + +[Term] +id: GO:0099553 +name: trans-synaptic signaling by endocannabinoid, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099542 ! trans-synaptic signaling by endocannabinoid +is_a: GO:0099552 ! trans-synaptic signaling by lipid, modulating synaptic transmission + +[Term] +id: GO:0099554 +name: trans-synaptic signaling by soluble gas, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099543 ! trans-synaptic signaling by soluble gas +is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission + +[Term] +id: GO:0099555 +name: trans-synaptic signaling by nitric oxide, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide +is_a: GO:0099554 ! trans-synaptic signaling by soluble gas, modulating synaptic transmission + +[Term] +id: GO:0099556 +name: trans-synaptic signaling by carbon monoxide, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099549 ! trans-synaptic signaling by carbon monoxide +is_a: GO:0099554 ! trans-synaptic signaling by soluble gas, modulating synaptic transmission + +[Term] +id: GO:0099557 +name: trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission +namespace: biological_process +def: "Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:19029886] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099545 ! trans-synaptic signaling by trans-synaptic complex +is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission + +[Term] +id: GO:0099558 +name: maintenance of synapse structure +namespace: biological_process +def: "A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds." [GOC:dos, PMID:24449494, PMID:25611509] +subset: goslim_synapse +synonym: "synaptic maintenance" EXACT [] +is_a: GO:0034331 ! cell junction maintenance +is_a: GO:0050808 ! synapse organization + +[Term] +id: GO:0099559 +name: maintenance of alignment of postsynaptic density and presynaptic active zone +namespace: biological_process +def: "The process by which alignment between postsynaptic density and presynaptic active zone is maintained." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099558 ! maintenance of synapse structure + +[Term] +id: GO:0099560 +name: synaptic membrane adhesion +namespace: biological_process +def: "The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane." [GOC:dos] +subset: goslim_synapse +synonym: "synapse adhesion between pre- and post-synapse" EXACT syngo_official_label [] +is_a: GO:0098742 ! cell-cell adhesion via plasma-membrane adhesion molecules +relationship: part_of GO:0050808 ! synapse organization + +[Term] +id: GO:0099561 +name: synaptic membrane adhesion to extracellular matrix +namespace: biological_process +def: "The binding of a synaptic membrane to the extracellular matrix via adhesion molecules." [GOC:dos] +subset: goslim_synapse +is_a: GO:0007160 ! cell-matrix adhesion +relationship: part_of GO:0050808 ! synapse organization + +[Term] +id: GO:0099562 +name: maintenance of postsynaptic density structure +namespace: biological_process +def: "A process which maintains the organization and the arrangement of proteins in the presynaptic density." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098880 ! maintenance of postsynaptic specialization structure + +[Term] +id: GO:0099563 +name: modification of synaptic structure +namespace: biological_process +def: "Any process that modifies the structure/morphology of a synapse." [GOC:dos] +comment: This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones. +subset: goslim_synapse +synonym: "synapse remodelling" EXACT [] +is_a: GO:0050808 ! synapse organization + +[Term] +id: GO:0099564 +name: modification of synaptic structure, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission via modification of the structure of the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0099563 ! modification of synaptic structure + +[Term] +id: GO:0099565 +name: chemical synaptic transmission, postsynaptic +namespace: biological_process +def: "The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol." [GOC:dos] +subset: gocheck_do_not_annotate +subset: goslim_synapse +synonym: "postsynaptic process involved in chemical synaptic transmission" RELATED syngo_official_label [] +is_a: GO:0050877 ! nervous system process +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +intersection_of: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: occurs_in GO:0098794 ! postsynapse +intersection_of: part_of GO:0007268 ! chemical synaptic transmission +relationship: occurs_in GO:0098794 ! postsynapse +relationship: part_of GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099566 +name: regulation of postsynaptic cytosolic calcium ion concentration +namespace: biological_process +def: "Any process that regulates the concentration of calcium in the postsynaptic cytosol." [GOC:dos] +subset: goslim_synapse +synonym: "regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0051480 ! regulation of cytosolic calcium ion concentration +intersection_of: GO:0051480 ! regulation of cytosolic calcium ion concentration +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse + +[Term] +id: GO:0099567 +name: calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations." [PMID:24442513, PMID:26190970] +subset: goslim_synapse +synonym: "calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "postsynaptic calcium ion buffering" EXACT [] +synonym: "regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering" RELATED [] +is_a: GO:0099510 ! calcium ion binding involved in regulation of cytosolic calcium ion concentration +intersection_of: GO:0005509 ! calcium ion binding +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: occurs_in GO:0099524 ! postsynaptic cytosol +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099568 +name: cytoplasmic region +namespace: cellular_component +def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] +is_a: GO:0005737 ! cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm + +[Term] +id: GO:0099569 +name: presynaptic cytoskeleton +namespace: cellular_component +def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005856 ! cytoskeleton +intersection_of: GO:0005856 ! cytoskeleton +intersection_of: part_of GO:0098793 ! presynapse +relationship: part_of GO:0098793 ! presynapse + +[Term] +id: GO:0099571 +name: postsynaptic cytoskeleton +namespace: cellular_component +def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835] +subset: goslim_synapse +is_a: GO:0005856 ! cytoskeleton +intersection_of: GO:0005856 ! cytoskeleton +intersection_of: part_of GO:0098794 ! postsynapse +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0099572 +name: postsynaptic specialization +namespace: cellular_component +def: "A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components." [PMID:22046028] +subset: goslim_synapse +is_a: GO:0043226 ! organelle +relationship: part_of GO:0098794 ! postsynapse + +[Term] +id: GO:0099573 +name: glutamatergic postsynaptic density +namespace: cellular_component +def: "The post-synaptic specialization of a glutamatergic excitatory synapse." [GOC:dos] +subset: goslim_synapse +synonym: "postsynaptic specialization, glutamatergic neuron-to-neuron synapse" EXACT syngo_official_label [] +is_a: GO:0014069 ! postsynaptic density + +[Term] +id: GO:0099574 +name: regulation of protein catabolic process at synapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +is_a: GO:0140250 ! regulation protein catabolic process at synapse + +[Term] +id: GO:0099575 +name: regulation of protein catabolic process at presynapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0042176 ! regulation of protein catabolic process +is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission +intersection_of: GO:0042176 ! regulation of protein catabolic process +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099576 +name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0042176 ! regulation of protein catabolic process +is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission +intersection_of: GO:0042176 ! regulation of protein catabolic process +intersection_of: occurs_in GO:0098794 ! postsynapse +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099577 +name: regulation of translation at presynapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission +is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission +is_a: GO:0140244 ! regulation of translation at presynapse +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: regulates GO:0006412 ! translation +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099578 +name: regulation of translation at postsynapse, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission +is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission +is_a: GO:0140245 ! regulation of translation at postsynapse +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0098794 ! postsynapse +intersection_of: regulates GO:0006412 ! translation +intersection_of: regulates GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099579 +name: G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential." [GOC:dos] +subset: goslim_synapse +synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential" EXACT [] +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +is_a: GO:0099529 ! neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential +is_a: GO:0099530 ! G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential +intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0099580 +name: ion antiporter activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos] +subset: goslim_synapse +synonym: "ion antiporter activity involved in regulation of post-synaptic membrane potential" EXACT [] +is_a: GO:0015297 ! antiporter activity +relationship: occurs_in GO:0045211 ! postsynaptic membrane + +[Term] +id: GO:0099581 +name: ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential." [GOC:dos] +subset: goslim_synapse +synonym: "ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential" EXACT [] +synonym: "ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential" EXACT [] +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +intersection_of: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +relationship: occurs_in GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential + +[Term] +id: GO:0099582 +name: neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +synonym: "neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0030594 ! neurotransmitter receptor activity +intersection_of: GO:0030594 ! neurotransmitter receptor activity +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: occurs_in GO:0042734 ! presynaptic membrane +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099583 +name: neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol." [GOC:dos] +subset: goslim_synapse +synonym: "neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0098960 ! postsynaptic neurotransmitter receptor activity +intersection_of: GO:0030594 ! neurotransmitter receptor activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099585 +name: release of sequestered calcium ion into presynaptic cytosol +namespace: biological_process +def: "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0051209 ! release of sequestered calcium ion into cytosol +is_a: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration + +[Term] +id: GO:0099586 +name: release of sequestered calcium ion into postsynaptic cytosol +namespace: biological_process +def: "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0051209 ! release of sequestered calcium ion into cytosol +is_a: GO:0099588 ! positive regulation of postsynaptic cytosolic calcium concentration + +[Term] +id: GO:0099587 +name: inorganic ion import across plasma membrane +namespace: biological_process +def: "The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] +synonym: "inorganic ion import into cell" EXACT [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098660 ! inorganic ion transmembrane transport +is_a: GO:0098739 ! import across plasma membrane + +[Term] +id: GO:0099588 +name: positive regulation of postsynaptic cytosolic calcium concentration +namespace: biological_process +def: "Any process that increases the concentration of calcium ions in the postsynaptic cytosol." [GOC:dos] +subset: goslim_synapse +is_a: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +is_a: GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +intersection_of: GO:0007204 ! positive regulation of cytosolic calcium ion concentration +intersection_of: occurs_in GO:0098794 ! postsynapse + +[Term] +id: GO:0099589 +name: serotonin receptor activity +namespace: molecular_function +def: "Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates." [GOC:dos] +is_a: GO:0004888 ! transmembrane signaling receptor activity + +[Term] +id: GO:0099590 +name: neurotransmitter receptor internalization +namespace: biological_process +def: "A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor." [GOC:dos] +is_a: GO:0031623 ! receptor internalization +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0098657 ! import into cell +is_a: GO:0099637 ! neurotransmitter receptor transport + +[Term] +id: GO:0099592 +name: endocytosed synaptic vesicle processing via endosome +namespace: biological_process +def: "The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles." [GOC:dos] +synonym: "synaptic vesicle processing via endosome involved in synaptic vesicle recycling" EXACT [] +is_a: GO:0099003 ! vesicle-mediated transport in synapse +is_a: GO:0099532 ! synaptic vesicle endosomal processing +intersection_of: GO:0099532 ! synaptic vesicle endosomal processing +intersection_of: part_of GO:0036466 ! synaptic vesicle recycling via endosome +relationship: part_of GO:0036466 ! synaptic vesicle recycling via endosome + +[Term] +id: GO:0099593 +name: endocytosed synaptic vesicle to endosome fusion +namespace: biological_process +def: "Fusion of an endocytosed synaptic vesicle with an endosome." [GOC:dos] +is_a: GO:0016189 ! synaptic vesicle to endosome fusion +intersection_of: GO:0016189 ! synaptic vesicle to endosome fusion +intersection_of: part_of GO:0036466 ! synaptic vesicle recycling via endosome +relationship: part_of GO:0036466 ! synaptic vesicle recycling via endosome + +[Term] +id: GO:0099601 +name: regulation of neurotransmitter receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030594 ! neurotransmitter receptor activity +relationship: regulates GO:0030594 ! neurotransmitter receptor activity + +[Term] +id: GO:0099602 +name: neurotransmitter receptor regulator activity +namespace: molecular_function +def: "A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing." [GOC:dos, PMID:12740117, PMID:25172949] +is_a: GO:0030545 ! receptor regulator activity +relationship: part_of GO:0099601 ! regulation of neurotransmitter receptor activity + +[Term] +id: GO:0099604 +name: ligand-gated calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:dos] +is_a: GO:0005262 ! calcium channel activity +is_a: GO:0099094 ! ligand-gated cation channel activity +relationship: part_of GO:0019722 ! calcium-mediated signaling + +[Term] +id: GO:0099605 +name: regulation of action potential firing rate +namespace: biological_process +def: "Any process that regulates the frequency of action potentials in a spike train." [ISBN:978-0071390118] +is_a: GO:0098900 ! regulation of action potential + +[Term] +id: GO:0099606 +name: microtubule plus-end directed mitotic chromosome migration +namespace: biological_process +def: "The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression." [GOC:dos, PMID:26258632, PMID:26705896] +synonym: "plus-end directed chromosome gliding" EXACT [PMID:26258632] +is_a: GO:0007018 ! microtubule-based movement +is_a: GO:0051303 ! establishment of chromosome localization +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007080 ! mitotic metaphase plate congression + +[Term] +id: GO:0099607 +name: lateral attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate)." [PMID:26258632, PMID:26705896] +is_a: GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore + +[Term] +id: GO:0099608 +name: regulation of action potential firing pattern +namespace: biological_process +def: "Any process that regulates the temporal pattern of a sequence of action potentials in a neuron." [ISBN:978-0071390118] +synonym: "spike train sculpting" EXACT [] +is_a: GO:0098900 ! regulation of action potential +relationship: regulates GO:0098874 ! spike train + +[Term] +id: GO:0099609 +name: microtubule lateral binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the side of a microtubule." [GOC:dos] +is_a: GO:0008017 ! microtubule binding + +[Term] +id: GO:0099610 +name: action potential initiation +namespace: biological_process +def: "The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate." [ISBN:978-0071390118, PMID:19439602] +synonym: "action potential firing" EXACT [] +synonym: "action potential triggering" EXACT [] +is_a: GO:0001508 ! action potential + +[Term] +id: GO:0099611 +name: regulation of action potential firing threshold +namespace: biological_process +def: "Any process that regulates the potential at which an axon potential is triggered." [ISBN:978-0071390118] +is_a: GO:0098900 ! regulation of action potential + +[Term] +id: GO:0099612 +name: protein localization to axon +namespace: biological_process +def: "A process in which a protein is transported to or maintained in a location within an axon." [GOC:dos, PMID:26157139] +is_a: GO:0008104 ! protein localization + +[Term] +id: GO:0099613 +name: protein localization to cell wall +namespace: biological_process +def: "The process of directing proteins towards the cell-wall." [ISBN:0716731363] +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0099614 +name: protein localization to spore cell wall +namespace: biological_process +def: "A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall." [GOC:dos] +synonym: "protein targeting to spore cell wall" RELATED [] +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0099615 +name: (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor." [PMID:26774271] +synonym: "D-2HG-pyruvate transhydrogenase activity" EXACT [] +synonym: "R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity" EXACT [] +is_a: GO:0016614 ! oxidoreductase activity, acting on CH-OH group of donors + +[Term] +id: GO:0099616 +name: extrinsic component of matrix side of mitochondrial inner membrane +namespace: cellular_component +def: "The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region." [GOC:dos] +is_a: GO:0031314 ! extrinsic component of mitochondrial inner membrane +intersection_of: GO:0019898 ! extrinsic component of membrane +intersection_of: part_of GO:0099617 ! matrix side of mitochondrial inner membrane +relationship: part_of GO:0099617 ! matrix side of mitochondrial inner membrane + +[Term] +id: GO:0099617 +name: matrix side of mitochondrial inner membrane +namespace: cellular_component +def: "The side (leaflet) of the mitochondrial inner membrane that faces the matrix." [GOC:dos] +is_a: GO:0098576 ! lumenal side of membrane +relationship: part_of GO:0005743 ! mitochondrial inner membrane + +[Term] +id: GO:0099618 +name: UDP-glucuronic acid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+." [GOC:al, GOC:dos] +synonym: "UDP-GlcUA decarboxylase activity" EXACT [] +xref: EC:1.1.1.305 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0099619 +name: UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose." [PMID:15695810, PMID:15807526, PMID:15809294, PMID:15939024, PMID:17928292] +synonym: "10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity" EXACT [] +synonym: "ArnAFT activity" EXACT [] +synonym: "UDP-L-Ara4N formyltransferase activity" EXACT [] +xref: EC:2.1.2.13 +is_a: GO:0016742 ! hydroxymethyl-, formyl- and related transferase activity + +[Term] +id: GO:0099620 +name: UDP-4-amino-4-deoxy-L-arabinose aminotransferase +namespace: molecular_function +def: "Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate." [GOC:al, GOC:dos, PMID:12429098, PMID:12704196] +synonym: "UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase" EXACT [] +synonym: "UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase" EXACT [] +synonym: "UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase" EXACT [] +synonym: "UDP-Ara4O aminotransferase" EXACT [] +synonym: "UDP-L-Ara4N transaminase" EXACT [] +xref: EC:2.6.1.87 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0099621 +name: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity +namespace: molecular_function +alt_id: GO:0103019 +def: "Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate." [GOC:al, GOC:dos, PMID:11706007, PMID:15695810] +synonym: "Ara4FN transferase activity" EXACT [] +synonym: "undecaprenyl phosphate-L-Ara4FN transferase activity" EXACT [] +synonym: "undecaprenyl-phosphate Ara4FN transferase activity" EXACT [] +xref: EC:2.4.2.53 +xref: MetaCyc:RXN0-3521 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0099622 +name: cardiac muscle cell membrane repolarization +namespace: biological_process +def: "The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential." [GOC:BHF] +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0086009 ! membrane repolarization + +[Term] +id: GO:0099623 +name: regulation of cardiac muscle cell membrane repolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte." [GOC:BHF, GOC:dos, GOC:rl] +synonym: "heart repolarization" RELATED [] +synonym: "regulation of cardiac muscle cell repolarization" EXACT [] +synonym: "regulation of cardiomyocyte membrane repolarization" EXACT [] +is_a: GO:0060306 ! regulation of membrane repolarization +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099622 ! cardiac muscle cell membrane repolarization +relationship: regulates GO:0099622 ! cardiac muscle cell membrane repolarization + +[Term] +id: GO:0099624 +name: atrial cardiac muscle cell membrane repolarization +namespace: biological_process +def: "The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential." [GOC:BHF] +is_a: GO:0099622 ! cardiac muscle cell membrane repolarization + +[Term] +id: GO:0099625 +name: ventricular cardiac muscle cell membrane repolarization +namespace: biological_process +def: "The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] +is_a: GO:0099622 ! cardiac muscle cell membrane repolarization + +[Term] +id: GO:0099626 +name: voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels +namespace: molecular_function +def: "Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels." [GOC:dos, PMID:15548655] +subset: goslim_synapse +synonym: "voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0099511 ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: occurs_in GO:0098793 ! presynapse +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099627 +name: neurotransmitter receptor cycle +namespace: biological_process +def: "The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping)." [GOC:dos] +is_a: GO:0099637 ! neurotransmitter receptor transport + +[Term] +id: GO:0099628 +name: neurotransmitter receptor diffusion trapping +namespace: biological_process +def: "The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane." [PMID:18832033] +subset: goslim_synapse +is_a: GO:0098953 ! receptor diffusion trapping +relationship: occurs_in GO:0098590 ! plasma membrane region + +[Term] +id: GO:0099629 +name: postsynaptic specialization of symmetric synapse +namespace: cellular_component +def: "A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses." [PMID:18832033] +subset: goslim_synapse +synonym: "postsynaptic density of inhibitory synapse" EXACT [PMID:18832033] +is_a: GO:0099572 ! postsynaptic specialization +intersection_of: GO:0099572 ! postsynaptic specialization +intersection_of: part_of GO:0032280 ! symmetric synapse +relationship: part_of GO:0032280 ! symmetric synapse + +[Term] +id: GO:0099630 +name: postsynaptic neurotransmitter receptor cycle +namespace: biological_process +def: "The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane." [PMID:18832033] +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099627 ! neurotransmitter receptor cycle +intersection_of: GO:0099627 ! neurotransmitter receptor cycle +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse + +[Term] +id: GO:0099631 +name: postsynaptic endocytic zone cytoplasmic component +namespace: cellular_component +def: "The cytoplasmic component of the postsynaptic endocytic zone." [GOC:dos] +subset: goslim_synapse +synonym: "postsynaptic endocytic zone cytoplasmic component" EXACT [] +is_a: GO:0099738 ! cell cortex region +relationship: part_of GO:0098843 ! postsynaptic endocytic zone + +[Term] +id: GO:0099632 +name: protein transport within plasma membrane +namespace: biological_process +def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos] +is_a: GO:0032594 ! protein transport within lipid bilayer +relationship: occurs_in GO:0005886 ! plasma membrane + +[Term] +id: GO:0099633 +name: protein localization to postsynaptic specialization membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density)." [GOC:dos] +synonym: "protein localisation in postsynaptic specialization membrane" EXACT [GOC:TermGenie] +is_a: GO:0033365 ! protein localization to organelle +is_a: GO:1903539 ! protein localization to postsynaptic membrane + +[Term] +id: GO:0099634 +name: postsynaptic specialization membrane +namespace: cellular_component +def: "The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated." [GOC:dos] +subset: goslim_synapse +is_a: GO:0097060 ! synaptic membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0045211 ! postsynaptic membrane +intersection_of: part_of GO:0099572 ! postsynaptic specialization +relationship: part_of GO:0045211 ! postsynaptic membrane +relationship: part_of GO:0099572 ! postsynaptic specialization + +[Term] +id: GO:0099635 +name: voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels +namespace: molecular_function +def: "Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission." [GOC:dos] +subset: goslim_synapse +is_a: GO:0099626 ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +relationship: part_of GO:0099703 ! induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration + +[Term] +id: GO:0099636 +name: cytoplasmic streaming +namespace: biological_process +def: "The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains." [GOC:dos, Wikipedia:Cytoplasmic_streaming&oldid=706214009] +xref: Wikipedia:Cytoplasmic_streaming +is_a: GO:0016482 ! cytosolic transport + +[Term] +id: GO:0099637 +name: neurotransmitter receptor transport +namespace: biological_process +def: "The directed movement of neurotransmitter receptors." [GOC:dos] +subset: goslim_synapse +is_a: GO:0015031 ! protein transport +is_a: GO:0031503 ! protein-containing complex localization + +[Term] +id: GO:0099638 +name: endosome to plasma membrane protein transport +namespace: biological_process +def: "The directed movement of proteins from the endosome to the plasma membrane in transport vesicles." [GOC:dos] +is_a: GO:0006886 ! intracellular protein transport +is_a: GO:0061951 ! establishment of protein localization to plasma membrane +is_a: GO:1990126 ! retrograde transport, endosome to plasma membrane + +[Term] +id: GO:0099639 +name: neurotransmitter receptor transport, endosome to plasma membrane +namespace: biological_process +def: "The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles." [GOC:dos] +subset: goslim_synapse +is_a: GO:0098877 ! neurotransmitter receptor transport to plasma membrane +is_a: GO:0099638 ! endosome to plasma membrane protein transport + +[Term] +id: GO:0099640 +name: axo-dendritic protein transport +namespace: biological_process +def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194] +subset: goslim_synapse +synonym: "axonal protein transport" NARROW [] +is_a: GO:0008088 ! axo-dendritic transport +is_a: GO:0098840 ! protein transport along microtubule + +[Term] +id: GO:0099641 +name: anterograde axonal protein transport +namespace: biological_process +def: "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons." [GOC:dos] +subset: goslim_synapse +synonym: "anterograde axon cargo transport" BROAD [] +is_a: GO:0008089 ! anterograde axonal transport +is_a: GO:0099640 ! axo-dendritic protein transport +is_a: GO:1905383 ! protein localization to presynapse + +[Term] +id: GO:0099642 +name: retrograde axonal protein transport +namespace: biological_process +def: "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] +subset: goslim_synapse +synonym: "retrograde axon cargo transport" BROAD [] +is_a: GO:0008090 ! retrograde axonal transport +is_a: GO:0099640 ! axo-dendritic protein transport + +[Term] +id: GO:0099643 +name: signal release from synapse +namespace: biological_process +def: "Any signal release from a synapse." [GOC:dos] +subset: goslim_synapse +is_a: GO:0023061 ! signal release +intersection_of: GO:0023061 ! signal release +intersection_of: occurs_in GO:0045202 ! synapse +relationship: occurs_in GO:0045202 ! synapse +relationship: part_of GO:0099536 ! synaptic signaling + +[Term] +id: GO:0099644 +name: protein localization to presynaptic membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane." [GOC:dos] +synonym: "protein localisation in presynaptic membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to presynaptic membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in presynaptic membrane" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1905383 ! protein localization to presynapse +is_a: GO:1990778 ! protein localization to cell periphery + +[Term] +id: GO:0099645 +name: neurotransmitter receptor localization to postsynaptic specialization membrane +namespace: biological_process +def: "A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density)." [GOC:dos] +subset: goslim_synapse +synonym: "neurotransmitter receptor localisation in postsynaptic specialization membrane" EXACT [GOC:TermGenie] +is_a: GO:0097120 ! receptor localization to synapse +is_a: GO:0099072 ! regulation of postsynaptic membrane neurotransmitter receptor levels +is_a: GO:0099633 ! protein localization to postsynaptic specialization membrane + +[Term] +id: GO:0099646 +name: neurotransmitter receptor transport, plasma membrane to endosome +namespace: biological_process +def: "Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome." [GOC:dos] +subset: goslim_synapse +is_a: GO:0036010 ! protein localization to endosome +is_a: GO:0048227 ! plasma membrane to endosome transport +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0099637 ! neurotransmitter receptor transport + +[Term] +id: GO:0099699 +name: integral component of synaptic membrane +namespace: cellular_component +def: "The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos] +subset: goslim_synapse +is_a: GO:0005887 ! integral component of plasma membrane +is_a: GO:0099240 ! intrinsic component of synaptic membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0097060 ! synaptic membrane +created_by: dos +creation_date: 2017-05-25T17:22:18Z + +[Term] +id: GO:0099703 +name: induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration +namespace: biological_process +def: "The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission." [GOC:dos, ISBN:9780071120005] +subset: goslim_synapse +is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission +is_a: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +is_a: GO:2000302 ! positive regulation of synaptic vesicle exocytosis +intersection_of: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +intersection_of: positively_regulates GO:0016079 ! synaptic vesicle exocytosis +relationship: part_of GO:0007268 ! chemical synaptic transmission + +[Term] +id: GO:0099738 +name: cell cortex region +namespace: cellular_component +def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] +synonym: "perimembrane region" EXACT [] +is_a: GO:0005938 ! cell cortex +is_a: GO:0099568 ! cytoplasmic region +intersection_of: GO:0005938 ! cell cortex +intersection_of: part_of GO:0005938 ! cell cortex +relationship: part_of GO:0005938 ! cell cortex + +[Term] +id: GO:0100001 +name: regulation of skeletal muscle contraction by action potential +namespace: biological_process +def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] +is_a: GO:0001508 ! action potential +is_a: GO:0014819 ! regulation of skeletal muscle contraction +intersection_of: GO:0001508 ! action potential +intersection_of: regulates GO:0003009 ! skeletal muscle contraction +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100002 +name: negative regulation of protein kinase activity by protein phosphorylation +namespace: biological_process +def: "Any protein phosphorylation process that negatively regulates protein kinase activity." [GOC:cjm, GOC:obol] +is_a: GO:0006468 ! protein phosphorylation +is_a: GO:0006469 ! negative regulation of protein kinase activity +intersection_of: GO:0006468 ! protein phosphorylation +intersection_of: negatively_regulates GO:0004672 ! protein kinase activity +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100003 +name: obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100004 +name: obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100005 +name: obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100006 +name: obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100007 +name: obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100008 +name: regulation of fever generation by prostaglandin biosynthetic process +namespace: biological_process +def: "Any prostaglandin biosynthetic process process that regulates fever generation." [GOC:cjm, GOC:obol] +is_a: GO:0001516 ! prostaglandin biosynthetic process +is_a: GO:0031620 ! regulation of fever generation +intersection_of: GO:0001516 ! prostaglandin biosynthetic process +intersection_of: regulates GO:0001660 ! fever generation +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100009 +name: regulation of fever generation by prostaglandin secretion +namespace: biological_process +def: "Any prostaglandin secretion process that regulates fever generation." [GOC:cjm, GOC:obol] +is_a: GO:0031620 ! regulation of fever generation +is_a: GO:0032310 ! prostaglandin secretion +intersection_of: GO:0032310 ! prostaglandin secretion +intersection_of: regulates GO:0001660 ! fever generation +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100010 +name: positive regulation of fever generation by prostaglandin biosynthetic process +namespace: biological_process +def: "Any prostaglandin biosynthetic process process that positively_regulates fever generation." [GOC:cjm, GOC:obol] +is_a: GO:0031622 ! positive regulation of fever generation +is_a: GO:0100008 ! regulation of fever generation by prostaglandin biosynthetic process +intersection_of: GO:0001516 ! prostaglandin biosynthetic process +intersection_of: positively_regulates GO:0001660 ! fever generation +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100011 +name: positive regulation of fever generation by prostaglandin secretion +namespace: biological_process +def: "Any prostaglandin secretion process that positively_regulates fever generation." [GOC:cjm, GOC:obol] +is_a: GO:0031622 ! positive regulation of fever generation +is_a: GO:0100009 ! regulation of fever generation by prostaglandin secretion +intersection_of: GO:0032310 ! prostaglandin secretion +intersection_of: positively_regulates GO:0001660 ! fever generation +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100012 +name: regulation of heart induction by canonical Wnt signaling pathway +namespace: biological_process +def: "Any canonical Wnt signaling pathway process that regulates heart induction." [GOC:cjm, GOC:obol] +is_a: GO:0060070 ! canonical Wnt signaling pathway +is_a: GO:0090381 ! regulation of heart induction +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: regulates GO:0003129 ! heart induction +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100013 +name: obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100014 +name: obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100015 +name: obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100016 +name: obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100017 +name: obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100018 +name: obsolete regulation of glucose import by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100019 +name: obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling." [GOC:cjm, GOC:obol] +comment: The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14279 xsd:anyURI +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100020 +name: obsolete regulation of transport by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100021 +name: obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:0100022 +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of iron ion import by transcription from RNA polymerase II promoter" RELATED [] +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100023 +name: obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100024 +name: obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100025 +name: obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100026 +name: positive regulation of DNA repair by transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any transcription from RNA polymerase II promoter process that positively regulates DNA repair." [GOC:cjm, GOC:obol] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:0045739 ! positive regulation of DNA repair +intersection_of: GO:0006366 ! transcription by RNA polymerase II +intersection_of: positively_regulates GO:0006281 ! DNA repair +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100027 +name: obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis." [GOC:cjm, GOC:obol] +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100028 +name: obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100029 +name: obsolete regulation of histone modification by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100030 +name: obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100031 +name: obsolete regulation of histone methylation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100032 +name: obsolete positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phospholipid biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100033 +name: obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100034 +name: obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100035 +name: obsolete negative regulation of transmembrane transport by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates transmembrane transport." [GOC:cjm, GOC:obol] +comment: The term was obsoleted because it is better represented by a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100036 +name: obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates purine nucleotide biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100037 +name: obsolete positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates cellular alcohol catabolic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100038 +name: obsolete regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100039 +name: obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100040 +name: obsolete negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates invasive growth in response to glucose limitation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100041 +name: obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100042 +name: obsolete negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates pseudohyphal growth." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100043 +name: obsolete negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular response to alkaline pH." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100044 +name: obsolete negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular hyperosmotic salinity response." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100045 +name: negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any transcription from RNA polymerase II promoter process that negatively regulates arginine catabolic process." [GOC:cjm, GOC:obol] +is_a: GO:0006366 ! transcription by RNA polymerase II +is_a: GO:1900082 ! negative regulation of arginine catabolic process +intersection_of: GO:0006366 ! transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0006527 ! arginine catabolic process +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100046 +name: obsolete positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates arginine biosynthetic process." [GOC:cjm, GOC:obol] +comment: GO:0100046 +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100047 +name: obsolete negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates inositol biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100048 +name: obsolete positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylcholine biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100049 +name: obsolete negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylcholine biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100050 +name: obsolete negative regulation of mating type switching by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates mating type switching." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100051 +name: obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates meiotic nuclear division." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100052 +name: obsolete negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates G1/S transition of mitotic cell cycle." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100053 +name: obsolete positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfate assimilation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100054 +name: obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100055 +name: obsolete positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylserine biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100056 +name: obsolete negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylserine biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100057 +name: obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100058 +name: obsolete positive regulation of phenotypic switching by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phenotypic switching." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100059 +name: obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100060 +name: obsolete negative regulation of SREBP signaling pathway by DNA binding +namespace: molecular_function +def: "OBSOLETE. Any DNA binding that negatively regulates SREBP signaling pathway." [GOC:cjm, GOC:obol] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100061 +name: obsolete negative regulation of SREBP signaling pathway by transcription factor catabolic process +namespace: biological_process +def: "OBSOLETE. Any transcription factor catabolic process process that negatively regulates SREBP signaling pathway." [GOC:cjm, GOC:obol] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100062 +name: obsolete positive regulation of SREBP signaling pathway by transcription factor catabolic process +namespace: biological_process +def: "OBSOLETE. Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway." [GOC:cjm, GOC:obol] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100063 +name: obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport." [GOC:cjm, GOC:obol] +comment: The term was obsoleted because it is better represented by a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100064 +name: obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates filamentous growth of a population of unicellular organisms in response to starvation." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100065 +name: obsolete negative regulation of leucine import by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates leucine import." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100066 +name: obsolete negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates induction of conjugation with cellular fusion." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100067 +name: positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway +namespace: biological_process +def: "Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation." [GOC:cjm, GOC:obol] +is_a: GO:0060070 ! canonical Wnt signaling pathway +is_a: GO:1902831 ! positive regulation of spinal cord association neuron differentiation +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: positively_regulates GO:0021527 ! spinal cord association neuron differentiation +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100068 +name: obsolete positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pyrimidine-containing compound salvage." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100069 +name: obsolete negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates neuron apoptotic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0100070 +name: obsolete obsolete regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process." [GOC:cjm, GOC:obol] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: cjm +creation_date: 2015-04-02T04:13:19Z + +[Term] +id: GO:0101002 +name: ficolin-1-rich granule +namespace: cellular_component +def: "Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry." [GOC:mec, PMID:19741154] +synonym: "ficolin granule" RELATED [] +synonym: "ficolin-1 rich granule" EXACT [] +is_a: GO:0030141 ! secretory granule + +[Term] +id: GO:0101003 +name: ficolin-1-rich granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a ficolin-1-rich granule." [GOC:mec, PMID:23650620] +is_a: GO:0030667 ! secretory granule membrane +relationship: part_of GO:0070820 ! tertiary granule +created_by: mec + +[Term] +id: GO:0101004 +name: cytolytic granule membrane +namespace: cellular_component +def: "The lipid bilayer surrounding the cytolytic granule." [PMID:17272266, PMID:21247065] +is_a: GO:0005765 ! lysosomal membrane +created_by: mec +creation_date: 2015-12-15T04:32:00Z + +[Term] +id: GO:0101005 +name: ubiquitinyl hydrolase activity +namespace: molecular_function +alt_id: GO:1904265 +def: "Catalysis of the hydrolysis of ubiquitin from proteins and other molecules." [GOC:mec] +comment: There are two main classes of deubiquitinating enzymes: cysteine proteases (i.e., thiol dependent) and metalloproteases. +synonym: "deubiquitinase activity" EXACT [] +synonym: "ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol" NARROW [] +is_a: GO:0016787 ! hydrolase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: mec +creation_date: 2016-02-08T09:39:38Z + +[Term] +id: GO:0101006 +name: protein histidine phosphatase activity +namespace: molecular_function +alt_id: GO:0008969 +def: "Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate." [GOC:mec] +synonym: "phosphohistidine phosphatase activity" BROAD [] +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0101007 +name: negative regulation of transcription from RNA polymerase II promoter in response to salt stress +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:mec] +is_a: GO:0061416 ! regulation of transcription from RNA polymerase II promoter in response to salt stress +created_by: mec + +[Term] +id: GO:0101008 +name: negative regulation of transcription from RNA polymerase II promoter in response to increased salt +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment." [GOC:mec] +is_a: GO:0101007 ! negative regulation of transcription from RNA polymerase II promoter in response to salt stress +created_by: mec + +[Term] +id: GO:0101010 +name: pulmonary blood vessel remodeling +namespace: biological_process +def: "The reorganization or renovation of existing pulmonary blood vessels." [GOC:mec] +is_a: GO:0001974 ! blood vessel remodeling + +[Term] +id: GO:0101011 +name: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate." [GOC:mah, PMID:26422458] +synonym: "inositol 1-pyrophosphate 2,3,4,5,6-pentakisphosphate 1-pyrophosphatase activity" EXACT [] +is_a: GO:0052745 ! inositol phosphate phosphatase activity + +[Term] +id: GO:0101012 +name: inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate." [GOC:mah, PMID:26422458] +synonym: "inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity" EXACT [] +is_a: GO:0052745 ! inositol phosphate phosphatase activity + +[Term] +id: GO:0101013 +name: mechanosensitive voltage-gated sodium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [PMID:21041530, PMID:26838316] +synonym: "mechanically-modulated voltage-gated sodium channel activity" EXACT [] +is_a: GO:0005248 ! voltage-gated sodium channel activity +is_a: GO:0140135 ! mechanosensitive cation channel activity +intersection_of: GO:0005248 ! voltage-gated sodium channel activity +intersection_of: GO:0008381 ! mechanosensitive ion channel activity + +[Term] +id: GO:0101014 +name: [isocitrate dehydrogenase (NADP+)] phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate." [PMID:6292732] +synonym: "isocitrate dehydrogenase kinase/phosphatase activity" BROAD [EC:2.7.11.5] +xref: MetaCyc:ICITDEHASE-KIN-PHOSPHA +is_a: GO:0004721 ! phosphoprotein phosphatase activity + +[Term] +id: GO:0101016 +name: FMN-binding domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the FMN-binding domain of a protein." [PMID:15752726] +is_a: GO:0019904 ! protein domain specific binding + +[Term] +id: GO:0101017 +name: regulation of mitotic DNA replication initiation from late origin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication." [PMID:26436827] +synonym: "regulation of late replication origin firing" EXACT [GOC:dph, GOC:krc, PMID:19221029] +is_a: GO:1903466 ! regulation of mitotic DNA replication initiation +created_by: mec + +[Term] +id: GO:0101018 +name: negative regulation of mitotic DNA replication initiation from late origin +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication." [PMID:26436827] +synonym: "negative regulation of late replication origin firing" EXACT [GOC:dph, GOC:krc, PMID:19221029] +is_a: GO:0101017 ! regulation of mitotic DNA replication initiation from late origin +is_a: GO:1903467 ! negative regulation of mitotic DNA replication initiation +created_by: mec + +[Term] +id: GO:0101019 +name: nucleolar exosome (RNase complex) +namespace: cellular_component +def: "A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured." [PMID:17174896, PMID:20531386, PMID:26726035] +is_a: GO:0000176 ! nuclear exosome (RNase complex) +intersection_of: GO:0000178 ! exosome (RNase complex) +intersection_of: part_of GO:0005730 ! nucleolus +relationship: part_of GO:0005730 ! nucleolus +created_by: bhm + +[Term] +id: GO:0101020 +name: estrogen 16-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O." [GOC:BHF] +synonym: "oestrogen 16-alpha-hydroxylase activity" EXACT [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0101021 +name: estrogen 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O." [GOC:BHF, GOC:rl, PMID:14559847] +synonym: "oestrogen 2-hydroxylase activity" EXACT [] +is_a: GO:0008395 ! steroid hydroxylase activity +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0101023 +name: vascular endothelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774] +is_a: GO:0001935 ! endothelial cell proliferation + +[Term] +id: GO:0101024 +name: nuclear membrane organization involved in mitotic nuclear division +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane during mitotic nuclear division." [GOC:vw, PMID:15147872] +comment: This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown. +is_a: GO:0071763 ! nuclear membrane organization +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0140014 ! mitotic nuclear division +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0101025 +name: nuclear membrane biogenesis +namespace: biological_process +def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw] +is_a: GO:0044091 ! membrane biogenesis +relationship: part_of GO:0071763 ! nuclear membrane organization + +[Term] +id: GO:0101026 +name: nuclear membrane biogenesis involved in mitotic nuclear division +namespace: biological_process +def: "A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division." [GOC:vw, PMID:26869222] +is_a: GO:0061024 ! membrane organization +is_a: GO:0101025 ! nuclear membrane biogenesis +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0140014 ! mitotic nuclear division +property_value: RO:0002161 NCBITaxon:33208 + +[Term] +id: GO:0101027 +name: optical nerve axon regeneration +namespace: biological_process +def: "The regrowth of axons of the optical nerve following their loss or damage." [GOC:pga, PMID:16699509] +is_a: GO:0031103 ! axon regeneration + +[Term] +id: GO:0101028 +name: positive regulation of liquid surface tension +namespace: biological_process +def: "Any process that activates or increases the surface tension of a liquid." [GOC:sl, PMID:20949060] +synonym: "positive regulation of surface tension of a liquid" EXACT [] +is_a: GO:0050828 ! regulation of liquid surface tension + +[Term] +id: GO:0101029 +name: negative regulation of liquid surface tension +namespace: biological_process +def: "Any process that prevents or reduces the surface tension of a liquid." [GOC:sl, PMID:20949060] +synonym: "negative regulation of surface tension of a liquid" EXACT [] +is_a: GO:0050828 ! regulation of liquid surface tension + +[Term] +id: GO:0101030 +name: tRNA-guanine transglycosylation +namespace: biological_process +def: "The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine." [GOC:PomBase, GOC:vw, PMID:24911101] +is_a: GO:0006400 ! tRNA modification + +[Term] +id: GO:0101031 +name: chaperone complex +namespace: cellular_component +def: "A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins." [GOC:bhm, PMID:21855797] +comment: An example of this is HSP90AB1 in human (P08238) in PMID:21855797 (inferred from direct assay). +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0102001 +name: isoleucine N-monooxygenase (oxime forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O." [EC:1.14.14.39] +xref: EC:1.14.14.39 +xref: MetaCyc:1.14.13.117-RXN +xref: RHEA:28602 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102002 +name: valine N-monooxygenase (oxime forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O." [EC:1.14.14.38] +xref: EC:1.14.14.38 +xref: MetaCyc:1.14.13.118-RXN +xref: RHEA:28606 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102003 +name: Delta8-sphingolipid desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.4] +xref: EC:1.14.19.4 +xref: MetaCyc:1.14.19.4-RXN +is_a: GO:0052631 ! sphingolipid delta-8 desaturase activity + +[Term] +id: GO:0102004 +name: 2-octaprenyl-6-hydroxyphenol methylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine." [EC:2.1.1.222] +xref: MetaCyc:2-OCTAPRENYL-6-OHPHENOL-METHY-RXN +is_a: GO:1990888 ! 2-polyprenyl-6-hydroxyphenol O-methyltransferase activity + +[Term] +id: GO:0102006 +name: 4-methyl-2-oxopentanoate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-)." [EC:1.2.1.-] +xref: MetaCyc:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102007 +name: acyl-L-homoserine-lactone lactonohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine." [EC:3.1.1.81] +xref: EC:3.1.1.81 +xref: MetaCyc:3.1.1.81-RXN +xref: Reactome:R-HSA-8932633 "PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE" +is_a: GO:0046573 ! lactonohydrolase activity + +[Term] +id: GO:0102008 +name: cytosolic dipeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a dipeptide <=> 2 a standard alpha amino acid that occurs in the cytosol." [EC:3.4.13.18] +xref: EC:3.4.13.18 +xref: MetaCyc:3.4.13.18-RXN +is_a: GO:0016805 ! dipeptidase activity + +[Term] +id: GO:0102009 +name: proline dipeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid." [EC:3.4.13.9] +xref: EC:3.4.13.9 +xref: MetaCyc:3.4.13.9-RXN +is_a: GO:0016805 ! dipeptidase activity + +[Term] +id: GO:0102013 +name: ATPase-coupled L-glutamate tranmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in)." [EC:7.4.2.1] +synonym: "L-glutamate-importing ATPase activity" RELATED [] +xref: MetaCyc:ABC-13-RXN +is_a: GO:0015426 ! ATPase-coupled polar amino acid-transporter activity + +[Term] +id: GO:0102014 +name: beta-D-galactose-importing ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+." [EC:3.6.3.17] +xref: MetaCyc:ABC-18-RXN +is_a: GO:0015407 ! ATPase-coupled monosaccharide transmembrane transporter activity + +[Term] +id: GO:0102025 +name: ATPase-coupled thiosulfate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0032146 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in)." [EC:7.3.2.3, GOC:mlg, GOC:pz] +synonym: "thiosulfate transmembrane-transporting ATPase activity" RELATED [] +synonym: "thiosulphate ABC transporter activity" EXACT [] +xref: EC:7.3.2.3 +xref: MetaCyc:ABC-7-RXN +is_a: GO:0015117 ! thiosulfate transmembrane transporter activity +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14642 xsd:anyURI + +[Term] +id: GO:0102027 +name: S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine." [GOC:pz, RHEA:30063] +xref: EC:2.1.1.163 +xref: MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN +xref: RHEA:30063 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102028 +name: cystathionine gamma-synthase activity (acts on O-phosphohomoserine) +namespace: molecular_function +def: "Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate." [EC:2.5.1.-, GOC:pz] +xref: MetaCyc:CYSPH-RXN +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102029 +name: D-lactate dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol." [EC:1.1.5.-, GOC:pz] +xref: MetaCyc:DLACTDEHYDROGFAD-RXN +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0102030 +name: dTDP-L-rhamnose synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+." [EC:1.1.1.-, GOC:pz, MetaCyc:DTDPRHAMSYNTHMULTI-RXN] +xref: MetaCyc:DTDPRHAMSYNTHMULTI-RXN +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102031 +name: 4-acetamido-4,6-dideoxy-D-galactose transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP." [EC:2.4.1.325, GOC:pz] +xref: EC:2.4.1.325 +xref: MetaCyc:FUC4NACTRANS-RXN +xref: RHEA:28759 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102033 +name: fatty acid omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: long-chain fatty acid + NADPH + H+ + O2 = an omega-hydroxy-long-chain fatty acid + NADP+ + H2O." [GOC:pz, PMID:18544608] +synonym: "cytochrome P450 fatty acid omega-hydroxylase activity" RELATED [] +xref: EC:1.14.13.205 +xref: MetaCyc:RXN-16394 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14194 xsd:anyURI + +[Term] +id: GO:0102035 +name: isobutyryl-CoA:FAD oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2." [EC:1.3.8.-, GOC:pz, MetaCyc:MEPROPCOA-FAD-RXN] +xref: MetaCyc:MEPROPCOA-FAD-RXN +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102036 +name: methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein]." [EC:2.1.1.258, GOC:pz] +xref: EC:2.1.1.258 +xref: MetaCyc:METHCOCLTH-RXN +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102037 +name: 4-nitrotoluene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O." [EC:1.14.13.-, GOC:pz, MetaCyc:R361-RXN] +xref: MetaCyc:R361-RXN +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102038 +name: 4-nitrobenzyl alcohol oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide." [EC:1.1.3.-, GOC:pz] +xref: MetaCyc:R362-RXN +is_a: GO:0016899 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor + +[Term] +id: GO:0102039 +name: alkylhydroperoxide reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide." [EC:1.8.1.-, GOC:pz] +xref: MetaCyc:R4-RXN +is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + +[Term] +id: GO:0102040 +name: fumarate reductase (menaquinone) +namespace: molecular_function +def: "Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone." [EC:1.3.5.4, GOC:pz] +xref: EC:1.3.5.4 +xref: MetaCyc:R601-RXN +is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor + +[Term] +id: GO:0102041 +name: 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase +namespace: molecular_function +def: "Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid." [EC:2.5.1.105, GOC:pz] +xref: EC:2.5.1.105 +xref: MetaCyc:RXN-10009 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102042 +name: dehydroquinate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+." [GOC:pz, RHEA:25956] +xref: EC:1.4.1.24 +xref: MetaCyc:RXN-10032 +xref: RHEA:25956 +is_a: GO:0016639 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102043 +name: isopentenyl phosphate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-)." [EC:2.7.4.26, GOC:pz] +xref: EC:2.7.4.26 +xref: MetaCyc:RXN-10068 +xref: RHEA:33963 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0102044 +name: 3-chlorobenzoate-4,5-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor." [EC:1.14.12.-, GOC:pz] +xref: MetaCyc:RXN-10421 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0102045 +name: 3-chlorobenzoate-3,4-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor." [EC:1.14.12.-, GOC:pz] +xref: MetaCyc:RXN-10422 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0102046 +name: 3,4-dichlorobenzoate-4,5-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor." [EC:1.14.12.-, GOC:pz] +xref: MetaCyc:RXN-10427 +is_a: GO:0016708 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + +[Term] +id: GO:0102047 +name: indole-3-acetyl-glycine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10429 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102048 +name: indole-3-acetyl-isoleucine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10430 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102049 +name: indole-3-acetyl-methionine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10431 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102050 +name: indole-3-acetyl-tyrosine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10432 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102051 +name: indole-3-acetyl-tryptophan synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10433 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102052 +name: indole-3-acetyl-proline synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10434 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102053 +name: (-)-jasmonoyl-isoleucine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10435 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102054 +name: maleylpyruvate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate." [EC:3.7.1.-, GOC:pz] +xref: MetaCyc:RXN-10447 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102055 +name: 12-hydroxyjasmonate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate." [EC:2.8.2.-, GOC:pz] +xref: MetaCyc:RXN-10451 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0102056 +name: 11-hydroxyjasmonate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate." [EC:2.8.2.-, GOC:pz] +xref: MetaCyc:RXN-10453 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0102057 +name: jasmonoyl-valine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10457 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102058 +name: jasmonoyl-leucine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-leucine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10459 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102059 +name: 2-cis,6-cis-farnesyl pyrophosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: prenyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphoric acid + 2-cis,6-cis-farnesyl diphosphate." [EC:2.5.1.92, GOC:pz] +xref: EC:2.5.1.92 +xref: MetaCyc:RXN-10481 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102060 +name: endo-alpha-bergamontene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid." [EC:4.2.3.54, GOC:pz] +xref: EC:4.2.3.54 +xref: MetaCyc:RXN-10482 +xref: RHEA:30471 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102061 +name: endo-beta-bergamontene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid." [EC:4.2.3.53, GOC:pz] +xref: EC:4.2.3.53 +xref: MetaCyc:RXN-10483 +xref: RHEA:30467 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102062 +name: alpha-santalene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid." [EC:4.2.3.50, GOC:pz] +xref: EC:4.2.3.50 +xref: MetaCyc:RXN-10567 +xref: RHEA:30463 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102063 +name: beta-curcumene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-10598 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102064 +name: gamma-curcumene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid." [EC:4.2.3.94, GOC:pz] +xref: EC:4.2.3.94 +xref: MetaCyc:RXN-10599 +xref: RHEA:32031 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102065 +name: patchoulene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-10602 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102066 +name: alpha-patchoulene synthase activityy +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-10603 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102067 +name: geranylgeranyl diphosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+." [EC:1.3.1.83, GOC:pz] +xref: EC:1.3.1.83 +xref: MetaCyc:RXN-10625 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102068 +name: alpha-humulene 10-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O." [EC:1.14.14.113, GOC:pz] +xref: EC:1.14.14.113 +xref: MetaCyc:RXN-10628 +xref: RHEA:32491 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102069 +name: zerumbone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+." [EC:1.1.1.326, GOC:pz] +xref: EC:1.1.1.326 +xref: MetaCyc:RXN-10629 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102070 +name: 18-hydroxyoleate peroxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol." [EC:1.11.-.-, GOC:pz] +xref: MetaCyc:RXN-1064 +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor + +[Term] +id: GO:0102071 +name: 9,10-epoxy-18-hydroxystearate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate." [EC:3.3.2.-, GOC:pz] +xref: MetaCyc:RXN-1065 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0102072 +name: 3-oxo-cis-Delta9-hexadecenoyl-[acp] reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP + a 3R-hydroxy cis Delta9-hexadecenoyl-[acp] <=> NADPH + H+ + a 3-oxo-cis-Delta9-hexadecenoyl-[acp]." [EC:1.1.1.100, GOC:pz] +xref: MetaCyc:RXN-10659 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102073 +name: OPC8-trans-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: OPC8-3-hydroxyacyl-CoA <=> OPC8-trans-2-enoyl-CoA + H2O." [EC:4.2.1.17, GOC:pz] +xref: MetaCyc:RXN-10697 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102074 +name: OPC6-trans-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA <=> OPC6-trans-2-enoyl-CoA + H2O." [EC:4.2.1.17, GOC:pz] +xref: MetaCyc:RXN-10704 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102075 +name: OPC4-trans-2-enoyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: OPC4-3-hydroxyacyl-CoA <=> OPC4-trans-2-enoyl-CoA + H2O." [EC:4.2.1.17, GOC:pz] +xref: MetaCyc:RXN-10705 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102076 +name: beta,beta-carotene-9',10'-cleaving oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone." [EC:1.13.11.71, GOC:pz] +xref: EC:1.13.11.71 +xref: MetaCyc:RXN-10741 +xref: RHEA:26389 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102077 +name: oleamide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium." [EC:3.5.1.99, GOC:pz] +xref: EC:3.5.1.99 +xref: MetaCyc:RXN-10756 +xref: RHEA:26506 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0102078 +name: methyl jasmonate methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonic acid <=> S-adenosyl-L-homocysteine + a methyl jasmonate." [EC:2.1.1.141, GOC:pz] +xref: EC:2.1.1.141 +xref: MetaCyc:RXN-10768 +xref: RHEA:13349 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102080 +name: phenylacetyl-coenzyme A:glycine N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A." [EC:2.3.1.192, GOC:pz] +xref: EC:2.3.1.192 +xref: MetaCyc:RXN-10821 +xref: RHEA:27850 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102081 +name: homotaurine:2-oxoglutarate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-)." [EC:2.6.1.-, GOC:pz] +xref: MetaCyc:RXN-10822 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0102082 +name: demethylrebeccamycin--D-glucose O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine." [EC:2.1.1.164, GOC:pz] +xref: EC:2.1.1.164 +xref: MetaCyc:RXN-10847 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102083 +name: 7,8-dihydromonapterin aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol." [GOC:pz, PMID:15107504] +xref: MetaCyc:RXN-10857 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0102084 +name: L-dopa O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.6, GOC:pz] +xref: EC:2.1.1.6 +xref: MetaCyc:RXN-10870 +is_a: GO:0008168 ! methyltransferase activity +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0102085 +name: N-(4-aminobenzoyl)-L-glutamate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10884 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102086 +name: N-vanillate-L-glutamate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10885 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102087 +name: N-benzoyl-L-glutamate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10886 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102088 +name: N-(4-hydroxybenzoyl)-L-glutamate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-10887 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102089 +name: dehydroscoulerine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+." [EC:1.21.3.-, GOC:pz] +xref: MetaCyc:RXN-10888 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0102090 +name: adrenaline O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine <=> metanephrine + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.6, GOC:pz] +xref: MetaCyc:RXN-10909 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102091 +name: phosphatidylinositol-5-phosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-10962 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102092 +name: 5-diphosphoinositol pentakisphosphate 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP." [EC:2.7.4.24, GOC:pz] +xref: EC:2.7.4.24 +xref: MetaCyc:RXN-10979 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0102093 +name: acrylate:acyl-coA CoA transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-10985 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102094 +name: S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a demethylmenaquinol <=> S-adenosyl-L-homocysteine + H+ + a menaquinol." [GOC:pz, PMID:1444716, PMID:9045837, RHEA:26466] +xref: EC:2.1.1.163 +xref: MetaCyc:RXN-11046 +xref: RHEA:26466 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102096 +name: decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+." [EC:2.4.1.289, GOC:pz] +xref: EC:2.4.1.289 +xref: MetaCyc:RXN-11070 +xref: RHEA:34487 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102097 +name: (22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O." [EC:1.14.14.147, GOC:pz] +xref: EC:1.14.14.147 +xref: MetaCyc:RXN-11101 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102098 +name: D-galacturonate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+." [EC:1.1.1.365, GOC:pz] +xref: EC:1.1.1.365 +xref: MetaCyc:RXN-11151 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102099 +name: FAD-dependent urate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O." [EC:1.14.13.113, GOC:pz] +xref: EC:1.14.13.113 +xref: MetaCyc:RXN-11186 +xref: RHEA:27329 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102100 +name: mycothiol-arsenate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O." [EC:2.8.4.2, GOC:pz] +xref: EC:2.8.4.2 +xref: MetaCyc:RXN-11187 +xref: RHEA:27349 +is_a: GO:0050497 ! transferase activity, transferring alkylthio groups + +[Term] +id: GO:0102101 +name: sterol 24C methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 26,27-dehydrozymosterol + S-adenosyl-L-methionine <=> 24-alkyl sterol 1 + S-adenosyl-L-homocysteine." [EC:2.1.1.43, GOC:pz] +xref: MetaCyc:RXN-11201 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102102 +name: homocarnosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate." [EC:6.3.2.11, GOC:pz] +xref: EC:6.3.2.11 +xref: MetaCyc:RXN-11222 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0102103 +name: demethoxycurcumin synthase +namespace: molecular_function +def: "Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide." [EC:2.3.1.219, GOC:pz] +xref: EC:2.3.1.219 +xref: MetaCyc:RXN-11223 +xref: RHEA:35119 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102104 +name: demethoxycurcumin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-11224 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102105 +name: demethoxycurcumin synthase activity from feruloylacetyl-CoA +namespace: molecular_function +def: "Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide." [GOC:pz, RHEA:35139] +xref: EC:2.3.1.219 +xref: MetaCyc:RXN-11225 +xref: RHEA:35139 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102106 +name: curcumin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide." [EC:2.3.1.217, GOC:pz] +xref: EC:2.3.1.217 +xref: MetaCyc:RXN-11226 +xref: RHEA:34823 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102109 +name: tricaffeoyl spermidine O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11261 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102111 +name: gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-113 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102113 +name: hypoxia-inducible factor-asparagine oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit." [GOC:pz, RHEA:54268] +xref: EC:1.14.11.30 +xref: MetaCyc:RXN-11321 +xref: RHEA:54268 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102114 +name: caprate dehydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: decanoate + NADPH + O2 + H+ <=> 10-hydroxycaprate + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11325 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102115 +name: peptidoglycan asparagine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid." [EC:6.3.1.-, GOC:pz] +xref: MetaCyc:RXN-11338 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0102116 +name: laurate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11340 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102117 +name: gibberellin A9 carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine." [EC:2.1.1.275, GOC:pz] +xref: EC:2.1.1.275 +xref: MetaCyc:RXN-11358 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102118 +name: gibberellin A4 carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine." [EC:2.1.1.276, GOC:pz] +xref: EC:2.1.1.276 +xref: MetaCyc:RXN-11359 +xref: RHEA:36107 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102119 +name: gibberellin A20 carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11360 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102121 +name: ceramidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid." [EC:3.5.1.23, GOC:pz] +xref: EC:3.5.1.23 +xref: MetaCyc:RXN-11375 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0102122 +name: gibberellin A34 carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz, RHEA:36127] +xref: MetaCyc:RXN-11384 +xref: RHEA:36127 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102123 +name: gibberellin A4 16alpha,17 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P)." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-11385 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102124 +name: gibberellin A12 16alpha,17 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P)." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-11387 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102125 +name: gibberellin A9 16alpha,17 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P)." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-11388 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102126 +name: coniferyl aldehyde 5-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-1142 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102127 +name: 8-oxoguanine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium." [EC:3.5.4.32, GOC:pz] +xref: EC:3.5.4.32 +xref: MetaCyc:RXN-11455 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0102128 +name: chalcone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-11468 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102130 +name: malonyl-CoA methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester." [GOC:pz, RHEA:17105] +xref: EC:2.1.1.197 +xref: MetaCyc:RXN-11475 +xref: RHEA:17105 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102131 +name: 3-oxo-glutaryl-[acp] methyl ester reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester." [EC:1.1.1.100, GOC:pz] +xref: EC:1.1.1.100 +xref: MetaCyc:RXN-11476 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102132 +name: 3-oxo-pimeloyl-[acp] methyl ester reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester." [EC:1.1.1.100, GOC:pz] +xref: EC:1.1.1.100 +xref: MetaCyc:RXN-11480 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102133 +name: limonene hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11493 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102134 +name: (22S)-22-hydroxy-campesterol C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11529 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102135 +name: (22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11530 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102136 +name: 3-epi-6-deoxocathasterone C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + NADPH + O2 <=> 6-deoxotyphasterol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11531 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102137 +name: 7-oxateasterone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11537 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102138 +name: 7-oxatyphasterol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11538 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102139 +name: 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate." [EC:3.7.1.13, GOC:pz] +xref: EC:3.7.1.13 +xref: MetaCyc:RXN-11543 +xref: RHEA:27870 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102140 +name: heparan sulfate N-deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine." [EC:3.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11557 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102141 +name: [chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate." [EC:2.8.2.-, GOC:pz] +xref: MetaCyc:RXN-11560 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0102142 +name: [dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate." [EC:2.8.2.-, GOC:pz] +xref: MetaCyc:RXN-11561 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0102143 +name: carboxynorspermidine dehydrogenase I activity +namespace: molecular_function +def: "Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+." [EC:1.5.1.43, GOC:pz] +xref: MetaCyc:RXN-11565 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102144 +name: carboxyspermidine dehydrogenase II activity +namespace: molecular_function +def: "Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+." [EC:1.5.1.43, GOC:pz] +xref: MetaCyc:RXN-11566 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102145 +name: (3R)-(E)-nerolidol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid." [EC:4.2.3.49, GOC:pz] +xref: EC:4.2.3.49 +xref: MetaCyc:RXN-11575 +xref: RHEA:27534 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102146 +name: tricetin O-methytransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11582 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102147 +name: 3'-O-methyltricetin O methyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11583 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102148 +name: N-acetyl-beta-D-galactosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan." [EC:3.2.1.52, GOC:pz] +xref: EC:3.2.1.52 +xref: MetaCyc:RXN-11622 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102149 +name: farnesylcysteine lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide." [EC:1.8.3.6, GOC:pz] +xref: EC:1.8.3.6 +xref: MetaCyc:RXN-11623 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + +[Term] +id: GO:0102150 +name: 3-oxo-myristoyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+." [EC:3.1.2.-, GOC:pz] +xref: MetaCyc:RXN-11668 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102151 +name: 3-oxo-myristate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide." [EC:4.1.1.56, GOC:pz] +xref: EC:4.1.1.56 +xref: MetaCyc:RXN-11669 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0102152 +name: Delta12-linoleate epoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11671 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102154 +name: 8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-11685 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102155 +name: S-sulfolactate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+." [EC:1.1.1.310, GOC:pz] +xref: EC:1.1.1.310 +xref: MetaCyc:RXN-11689 +xref: RHEA:28194 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102156 +name: 2,5-DHBA UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-11705 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102157 +name: (R)-sulfopropanediol 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11729 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102158 +name: very-long-chain 3-hydroxyacyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA." [GOC:pz, RHEA:45812] +xref: EC:4.2.1.134 +xref: MetaCyc:RXN-11750 +xref: RHEA:45812 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102159 +name: baicalein 7-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin." [EC:2.4.1.253, GOC:pz] +xref: EC:2.4.1.253 +xref: MetaCyc:RXN-11755 +xref: RHEA:28314 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102160 +name: cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP." [EC:2.4.1.254, GOC:pz] +xref: EC:2.4.1.254 +xref: MetaCyc:RXN-11756 +xref: RHEA:28258 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102161 +name: copal-8-ol diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O." [EC:4.2.1.133, GOC:pz] +xref: EC:4.2.1.133 +xref: MetaCyc:RXN-11772 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102162 +name: all-trans-8'-apo-beta-carotenal 15,15'-oxygenase +namespace: molecular_function +def: "Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial." [EC:1.13.11.75, GOC:pz] +xref: EC:1.13.11.75 +xref: MetaCyc:RXN-11783 +xref: RHEA:26385 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102163 +name: 3-hydroxyacyl-CoA-acyl carrier protein transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein]." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-11785 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102164 +name: 2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O." [EC:1.14.13.182, GOC:pz] +xref: EC:1.14.13.182 +xref: MetaCyc:RXN-11849 +xref: RHEA:37871 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102165 +name: (Z)-3-hexen-1-ol acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A." [EC:2.3.1.195, GOC:pz] +xref: EC:2.3.1.195 +xref: MetaCyc:RXN-11852 +xref: RHEA:28254 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102166 +name: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine." [EC:3.2.1.169, GOC:pz] +xref: EC:3.2.1.169 +xref: MetaCyc:RXN-11891 +xref: RHEA:48892 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102167 +name: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine." [EC:3.2.1.169, GOC:pz] +xref: EC:3.2.1.169 +xref: MetaCyc:RXN-11892 +xref: RHEA:48876 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102168 +name: 5-methyl-phenazine-1-carboxylate N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11897 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102169 +name: pyocyanin hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ <=> pyocyanin + NAD + carbon dioxide + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11898 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102170 +name: 5-epi-aristolochene-1,3-dihydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O." [EC:1.14.14.149, GOC:pz] +xref: EC:1.14.14.149 +xref: MetaCyc:RXN-11908 +xref: RHEA:28226 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102171 +name: DMNT synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11911 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102172 +name: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11925 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102173 +name: 24-methylenecycloartanol 4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11926 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102174 +name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11927 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102175 +name: 3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD <=> cycloeucalenone + NADH + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11928 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102176 +name: cycloeucalenone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11929 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102177 +name: 24-methylenelophenol methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11930 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102178 +name: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11932 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102179 +name: 24-ethylidenelophenol 4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11935 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102180 +name: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11936 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102181 +name: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11937 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102182 +name: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11938 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102183 +name: avenastenone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11939 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102184 +name: cycloartenol 4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11946 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102185 +name: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11947 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102186 +name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11948 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102187 +name: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol dehydrogenase/C4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) <=> 4alpha,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3-one + NADH(2-) + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11949 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102188 +name: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11956 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102189 +name: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11957 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102190 +name: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-11958 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102191 +name: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-11959 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102192 +name: neryl-diphosphate:isopentenyl-diphosphate cistransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: neryl diphosphate(3-) + isopentenyl diphosphate(3-) <=> diphosphoric acid + 2-cis,6-cis-farnesyl diphosphate(3-)." [EC:2.5.1.92, GOC:pz] +xref: EC:2.5.1.92 +xref: MetaCyc:RXN-11973 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102193 +name: protein-ribulosamine 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine." [EC:2.7.1.172, GOC:pz] +xref: EC:2.7.1.172 +xref: MetaCyc:RXN-12003 +xref: RHEA:48432 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0102194 +name: protein-fructosamine 3-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine." [EC:2.7.1.171, GOC:pz] +xref: EC:2.7.1.171 +xref: MetaCyc:RXN-12005 +xref: RHEA:59832 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0102195 +name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+." [EC:6.3.2.37, GOC:pz] +xref: EC:6.3.2.37 +xref: MetaCyc:RXN-12042 +xref: RHEA:25273 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0102196 +name: cortisol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12085 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102197 +name: vinylacetate caboxylester hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate." [EC:3.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12087 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102198 +name: L-idonate 5-dehydrogenase activity (NAD-dependent) +namespace: molecular_function +def: "Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+." [GOC:pz, RHEA:21172] +xref: EC:1.1.1.366 +xref: MetaCyc:RXN-12107 +xref: RHEA:21172 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102199 +name: nitric oxide reductase activity (NAD(P)H-dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H." [EC:1.7.1.14, GOC:pz] +xref: EC:1.7.1.14 +xref: MetaCyc:RXN-12112 +is_a: GO:0046857 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + +[Term] +id: GO:0102200 +name: N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate." [GOC:pz, RHEA:33159] +xref: EC:3.1.4.54 +xref: MetaCyc:RXN-12116 +xref: RHEA:33159 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0102201 +name: (+)-2-epi-prezizaene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-12117 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102202 +name: soladodine glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+." [EC:2.4.1.173, GOC:pz, RHEA:61844] +xref: EC:2.4.1.173 +xref: MetaCyc:RXN-12123 +xref: RHEA:61844 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102203 +name: brassicasterol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+." [EC:2.4.1.173, GOC:pz, RHEA:61840] +xref: EC:2.4.1.173 +xref: MetaCyc:RXN-12125 +xref: RHEA:61840 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102205 +name: cholesterol alpha-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+." [GOC:pz, RHEA:61848] +synonym: "cholesterol allpha-glucosyltransferase activity" EXACT [] +xref: EC:2.4.1.173 +xref: MetaCyc:RXN-12127 +xref: RHEA:61848 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102207 +name: very long chain fatty acid omega-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: behenate + NADPH + O2 + H+ = 22-hydroxydocosanoate + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-12155 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102208 +name: 2-polyprenyl-6-hydroxyphenol methylase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol." [EC:2.1.1.222, GOC:pz] +xref: MetaCyc:RXN-12160 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102209 +name: trans-permethrin hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate." [EC:3.1.1.88, GOC:pz] +xref: EC:3.1.1.88 +xref: MetaCyc:RXN-12167 +xref: RHEA:30283 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102210 +name: rhamnogalacturonan endolyase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide]." [EC:4.2.2.23, GOC:pz] +xref: EC:4.2.2.23 +xref: MetaCyc:RXN-12173 +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0102211 +name: unsaturated rhamnogalacturonyl hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose." [EC:3.2.1.172, GOC:pz] +xref: EC:3.2.1.172 +xref: MetaCyc:RXN-12174 +xref: RHEA:30927 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102212 +name: unsaturated chondroitin disaccharide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate." [EC:3.2.1.180, GOC:pz] +xref: EC:3.2.1.180 +xref: MetaCyc:RXN-12177 +xref: RHEA:31647 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102213 +name: in-chain hydroxy fatty acyl-CoA synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12184 +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0102214 +name: omega-hydroxy fatty acyl-CoA synthetase activity. +namespace: molecular_function +def: "Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12185 +is_a: GO:0015645 ! fatty acid ligase activity +is_a: GO:0016405 ! CoA-ligase activity + +[Term] +id: GO:0102215 +name: thiocyanate methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine <=> methyl thiocyanate + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12189 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102216 +name: maltodextrin water dikinase +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin." [EC:2.7.9.4, GOC:pz] +xref: EC:2.7.9.4 +xref: MetaCyc:RXN-12201 +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0102217 +name: 6-phosphoglucan, water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin." [GOC:pz, RHEA:10256] +xref: EC:2.7.9.5 +xref: MetaCyc:RXN-12202 +xref: RHEA:10256 +is_a: GO:0016781 ! phosphotransferase activity, paired acceptors + +[Term] +id: GO:0102218 +name: starch, H2O dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin." [EC:2.7.9.4, GOC:pz] +xref: EC:2.7.9.4 +xref: MetaCyc:RXN-12203 +is_a: GO:0050521 ! alpha-glucan, water dikinase activity + +[Term] +id: GO:0102219 +name: phosphogluco-amylopectin water dikinase activity +namespace: molecular_function +def: "Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin." [EC:2.7.9.5, GOC:pz] +xref: EC:2.7.9.5 +xref: MetaCyc:RXN-12204 +is_a: GO:0051752 ! phosphoglucan, water dikinase activity + +[Term] +id: GO:0102220 +name: hydrogenase activity (NAD+, ferredoxin) +namespace: molecular_function +def: "Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin." [GOC:pz, RHEA:30279] +xref: EC:1.12.1.4 +xref: MetaCyc:RXN-12215 +xref: RHEA:30279 +is_a: GO:0016696 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor + +[Term] +id: GO:0102222 +name: 6-phosophogluco-3-phosphogluco-starch phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: m+q H2O + a 6-phosphogluco-3-phosphogluco-amylopectin <=> m+q hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-12218 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102223 +name: 4,4'-diapophytoene desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD <=> 4,4'-diapolycopene + 4 FADH2." [EC:1.3.8.2, GOC:pz] +xref: EC:1.3.8.2 +xref: MetaCyc:RXN-12224 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102224 +name: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12236 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102225 +name: 4,4'-diaponeurosporene desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2." [EC:1.3.8.-, GOC:pz] +xref: MetaCyc:RXN-12258 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102229 +name: amylopectin maltohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose." [EC:3.2.1.2, GOC:pz] +xref: EC:3.2.1.2 +xref: MetaCyc:RXN-12278 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102232 +name: acrolein reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12281 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102233 +name: crotonaldehyde redutase activity +namespace: molecular_function +def: "Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12292 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102234 +name: but-1-en-3-one reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12293 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102235 +name: 1-penten-3-one reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12295 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102236 +name: trans-4-hexen-3-one reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12296 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102237 +name: ATP-dependent farnesol kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2-trans,6-trans)-farnesol + ATP(4-) <=> H+ + 2-trans,-6-trans-farnesyl monophosphate + ADP(3-)." [EC:2.7.1.-, GOC:pz] +xref: MetaCyc:RXN-12304 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0102238 +name: geraniol kinase activity (ATP-dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+." [EC:2.7.1.-, GOC:pz] +xref: MetaCyc:RXN-12307 +is_a: GO:0052670 ! geraniol kinase activity + +[Term] +id: GO:0102240 +name: soyasapogenol B glucuronide galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III." [EC:2.4.1.272, GOC:pz] +xref: EC:2.4.1.272 +xref: MetaCyc:RXN-12319 +xref: RHEA:31487 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102241 +name: soyasaponin III rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I." [EC:2.4.1.273, GOC:pz] +xref: EC:2.4.1.273 +xref: MetaCyc:RXN-12320 +xref: RHEA:31491 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102243 +name: ATP:geranylgeraniol phosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP." [GOC:pz, RHEA:61660] +xref: EC:2.7.1.216 +xref: MetaCyc:RXN-12325 +xref: RHEA:61660 +is_a: GO:0052671 ! geranylgeraniol kinase activity + +[Term] +id: GO:0102244 +name: 3-aminopropanal dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine + NADH." [EC:1.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12332 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102245 +name: lupan-3beta,20-diol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O." [EC:4.2.1.128, GOC:pz] +xref: EC:4.2.1.128 +xref: MetaCyc:RXN-12338 +xref: RHEA:31351 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102246 +name: 6-amino-6-deoxyfutalosine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine." [EC:3.2.2.30, GOC:pz] +xref: EC:3.2.2.30 +xref: MetaCyc:RXN-12346 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0102247 +name: malonyl-malonyl acyl carrier protein-condensing enzyme activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein]." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12361 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102248 +name: diacylglycerol transacylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12383 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102249 +name: phosphatidylcholine:diacylglycerol cholinephosphotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine." [EC:2.7.8.-, GOC:pz] +xref: MetaCyc:RXN-12386 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0102250 +name: linear malto-oligosaccharide phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide." [EC:2.4.1.1, GOC:pz] +xref: EC:2.4.1.1 +xref: MetaCyc:RXN-12392 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102251 +name: all-trans-beta-apo-10'-carotenal cleavage oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial." [EC:1.13.11.70, GOC:pz] +xref: EC:1.13.11.70 +xref: MetaCyc:RXN-12393 +xref: RHEA:26401 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102252 +name: cellulose 1,4-beta-cellobiosidase activity (reducing end) +namespace: molecular_function +def: "Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains." [EC:3.2.1.176, GOC:pz] +xref: EC:3.2.1.176 +xref: MetaCyc:RXN-12420 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102253 +name: neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside." [EC:3.2.1.159, GOC:pz] +xref: EC:3.2.1.159 +xref: MetaCyc:RXN-12426 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102254 +name: neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose." [EC:3.2.1.159, GOC:pz] +xref: EC:3.2.1.159 +xref: MetaCyc:RXN-12427 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102255 +name: neo-lambda-carrahexaose hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose." [EC:3.2.1.162, GOC:pz] +xref: EC:3.2.1.162 +xref: MetaCyc:RXN-12428 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102256 +name: neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose." [EC:3.2.1.159, GOC:pz] +xref: EC:3.2.1.159 +xref: MetaCyc:RXN-12429 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102257 +name: 1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+." [EC:3.1.1.32, GOC:pz] +xref: MetaCyc:RXN-12430 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102258 +name: 1,3-diacylglycerol acylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid." [EC:3.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12433 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102259 +name: 1,2-diacylglycerol acylhydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid." [EC:3.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12434 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102260 +name: germacrene A alcohol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-ol + 2 NADP + H2O <=> germacra-1(10),4,11(13)-trien-12-oate + 2 NADPH + 3 H+." [EC:1.1.1.314, GOC:pz] +xref: EC:1.1.1.314 +xref: MetaCyc:RXN-12449 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102261 +name: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420." [EC:1.5.1.40, GOC:pz] +xref: EC:1.5.1.40 +xref: MetaCyc:RXN-12450 +xref: RHEA:31363 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102262 +name: tRNA-dihydrouridine16 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H." [EC:1.3.1.88, GOC:pz] +xref: MetaCyc:RXN-12454 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102263 +name: tRNA-dihydrouridine17 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H." [EC:1.3.1.88, GOC:pz] +xref: EC:1.3.1.88 +xref: MetaCyc:RXN-12455 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102264 +name: tRNA-dihydrouridine20 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H." [EC:1.3.1.91, GOC:pz] +xref: EC:1.3.1.91 +xref: MetaCyc:RXN-12456 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102265 +name: tRNA-dihydrouridine47 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H." [EC:1.3.1.89, GOC:pz] +xref: EC:1.3.1.89 +xref: MetaCyc:RXN-12457 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102266 +name: tRNA-dihydrouridine20a synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H." [EC:1.3.1.90, GOC:pz] +xref: EC:1.3.1.90 +xref: MetaCyc:RXN-12475 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102267 +name: tRNA-dihydrouridine20b synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H." [EC:1.3.1.90, GOC:pz] +xref: MetaCyc:RXN-12476 +is_a: GO:0017150 ! tRNA dihydrouridine synthase activity + +[Term] +id: GO:0102272 +name: homophytochelatin synthase activity (polymer-forming) +namespace: molecular_function +def: "Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine." [EC:2.3.2.-, GOC:pz] +xref: MetaCyc:RXN-12528 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0102273 +name: homophytochelatin synthase (dimmer forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine." [EC:2.3.2.-, GOC:pz] +xref: MetaCyc:RXN-12529 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0102274 +name: glutathione S-conjugate carboxypeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate." [EC:3.4.17.-, GOC:pz] +xref: MetaCyc:RXN-12532 +is_a: GO:0004181 ! metallocarboxypeptidase activity + +[Term] +id: GO:0102275 +name: cysteine-S-conjugate N-malonyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12534 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102276 +name: 2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O." [EC:1.13.12.19, GOC:pz] +xref: EC:1.13.12.19 +xref: MetaCyc:RXN-12538 +xref: RHEA:31523 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0102277 +name: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12544 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102278 +name: N,N'-diacetylchitobiose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-12554 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102279 +name: lecithin:11-cis retinol acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine." [EC:2.3.1.135, GOC:pz] +xref: EC:2.3.1.135 +xref: MetaCyc:RXN-12563 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102280 +name: choline monooxygenase activity (NADP-dependent) +namespace: molecular_function +def: "Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12582 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102281 +name: formylaminopyrimidine deformylase activity +namespace: molecular_function +def: "Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate." [EC:3.5.1.-, GOC:pz] +xref: MetaCyc:RXN-12612 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0102282 +name: 3-ketodihydrosphinganine (C18) reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12641 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102283 +name: 3-ketodihydrosphinganine (C20) reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+." [EC:1.1.1.102, GOC:pz] +xref: MetaCyc:RXN-12642 +xref: RHEA:22640 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102284 +name: L-threo-sphinganine reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+)." [EC:1.1.1.102, GOC:pz] +xref: MetaCyc:RXN-12645 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102285 +name: 1-deoxy-11-oxopentalenate oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP." [GOC:pz, RHEA:34635] +xref: EC:1.14.13.170 +xref: MetaCyc:RXN-12654 +xref: RHEA:34635 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102286 +name: ornithine N-delta-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12667 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102287 +name: 4-coumaroylhexanoylmethane synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12668 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102289 +name: beta-amyrin 11-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP." [EC:1.14.14.152, GOC:pz] +xref: EC:1.14.14.152 +xref: MetaCyc:RXN-12680 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102290 +name: beta-amyrin monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP." [EC:1.14.14.152, GOC:pz] +xref: EC:1.14.14.152 +xref: MetaCyc:RXN-12681 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102291 +name: 11alpha-hydroxy-beta-amyrin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP." [EC:1.14.14.152, GOC:pz] +xref: EC:1.14.14.152 +xref: MetaCyc:RXN-12682 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102292 +name: 30-hydroxy-beta-amyrin 11-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-12683 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102293 +name: pheophytinase b activity +namespace: molecular_function +def: "Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol." [EC:3.1.1.14, GOC:pz] +xref: EC:3.1.1.14 +xref: MetaCyc:RXN-12686 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102294 +name: cholesterol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+." [EC:1.1.1.145, GOC:pz] +xref: EC:1.1.1.145 +xref: MetaCyc:RXN-12693 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102295 +name: 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12699 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102296 +name: 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+." [EC:3.7.1.17, GOC:pz] +xref: EC:3.7.1.17 +xref: MetaCyc:RXN-12718 +xref: RHEA:32035 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102297 +name: selenate adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid." [EC:2.7.7.4, GOC:pz] +xref: MetaCyc:RXN-12720 +is_a: GO:0016779 ! nucleotidyltransferase activity + +[Term] +id: GO:0102298 +name: selenocystathione synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine." [EC:2.5.1.-, GOC:pz] +xref: MetaCyc:RXN-12728 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102299 +name: linolenate 9R-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate." [EC:1.13.11.61, GOC:pz] +xref: EC:1.13.11.61 +xref: MetaCyc:RXN-12759 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102300 +name: linoleate 9R-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE." [GOC:pz, RHEA:31691] +xref: EC:1.13.11.61 +xref: MetaCyc:RXN-12760 +xref: RHEA:31691 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102301 +name: gamma-linolenate elongase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-12777 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102302 +name: mycinamicin VI 2''-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI <=> S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+." [EC:2.1.1.238, GOC:pz] +xref: EC:2.1.1.238 +xref: MetaCyc:RXN-12801 +xref: RHEA:31643 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102303 +name: resveratrol 3,5-O-dimethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine + pterostilbene + 2 H+." [EC:2.1.1.240, GOC:pz] +xref: EC:2.1.1.240 +xref: MetaCyc:RXN-12805 +xref: RHEA:32103 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102304 +name: sesquithujene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid." [EC:4.2.3.102, GOC:pz] +xref: EC:4.2.3.102 +xref: MetaCyc:RXN-12838 +xref: RHEA:31991 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102305 +name: (13E)-labda-7,13-dien-15-ol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid." [EC:3.1.7.10, GOC:pz] +xref: EC:3.1.7.10 +xref: MetaCyc:RXN-12892 +is_a: GO:0016794 ! diphosphoric monoester hydrolase activity + +[Term] +id: GO:0102306 +name: benzil reductase [(S)-benzoin-forming] activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+." [EC:1.1.1.320, GOC:pz] +xref: EC:1.1.1.320 +xref: MetaCyc:RXN-12898 +xref: RHEA:25968 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102307 +name: erythromycin C 3''-o-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+." [EC:2.1.1.254, GOC:pz] +xref: EC:2.1.1.254 +xref: MetaCyc:RXN-12923 +xref: RHEA:32647 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102308 +name: erythromycin D 3''-o-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+." [EC:2.1.1.254, GOC:pz] +xref: EC:2.1.1.254 +xref: MetaCyc:RXN-12924 +xref: RHEA:32651 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102309 +name: dTDP-4-oxo-2,6-dideoxy-D-glucose 4-ketoreductase (dTDP-D-oliose producing) activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-D-oliose + NADP <=> dTDP-4-dehydro-2,6-dideoxy-D-glucose + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-12930 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102310 +name: dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H." [EC:1.17.1.-, GOC:pz] +xref: MetaCyc:RXN-12940 +is_a: GO:0016726 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor + +[Term] +id: GO:0102311 +name: 8-hydroxygeraniol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+." [EC:1.1.1.324, GOC:pz] +xref: EC:1.1.1.324 +xref: MetaCyc:RXN-12961 +xref: RHEA:32659 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102312 +name: 4-coumaroyl 2'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-12963 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102313 +name: 1,8-cineole synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid." [EC:4.2.3.108, GOC:pz] +xref: EC:4.2.3.108 +xref: MetaCyc:RXN-12980 +xref: RHEA:32543 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102316 +name: L-dopa oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-dopa + 0.5 O2 = L-dopaquinone + H2O." [EC:1.10.3.-, GOC:pz] +xref: MetaCyc:RXN-13061 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0102317 +name: 4-methylaminobutyrate oxidase (demethylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(methylamino)butyric acid + O2 + H2O <=> gamma-aminobutyric acid + formaldehyde + hydrogen peroxide." [EC:1.5.3.19, GOC:pz] +xref: EC:1.5.3.19 +xref: MetaCyc:RXN-13067 +xref: RHEA:33907 +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor + +[Term] +id: GO:0102318 +name: 2-deoxystreptamine glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+." [EC:2.4.1.284, GOC:pz] +xref: EC:2.4.1.284 +xref: MetaCyc:RXN-13121 +xref: RHEA:34063 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102319 +name: 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-)." [EC:2.4.1.283, GOC:pz] +xref: EC:2.4.1.283 +xref: MetaCyc:RXN-13122 +xref: RHEA:33947 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102320 +name: 1,8-cineole 2-exo-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O." [EC:1.14.14.56, GOC:pz] +xref: EC:1.14.14.56 +xref: MetaCyc:RXN-13133 +xref: RHEA:32895 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102321 +name: 2,2'-hydroxybiphenyl monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD." [EC:1.14.13.44, GOC:pz] +xref: EC:1.14.13.44 +xref: MetaCyc:RXN-13150 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102322 +name: 2-propylphenol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13151 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102323 +name: 2-isopropylphenol monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13152 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102324 +name: 2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+." [EC:3.7.1.-, GOC:pz] +xref: MetaCyc:RXN-13157 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102325 +name: 2,2',3-trihydroxybiphenyl monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13169 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102326 +name: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+." [EC:3.7.1.8, GOC:pz] +xref: MetaCyc:RXN-13171 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102327 +name: 3-oxoacyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid." [EC:3.1.2.-, GOC:pz] +xref: MetaCyc:RXN-13247 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102328 +name: 3-oxoacid decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone." [EC:4.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13248 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0102329 +name: hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13251 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102330 +name: palmitoyl-[acp] elongase/decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-13258 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102331 +name: heptadecanoyl-[acp] elongase/decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-13259 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102332 +name: fatty-acyl-[acp] elongase/decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-13260 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102333 +name: stearoyl-[acp] elongase/decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-13261 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102334 +name: N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP." [EC:2.7.8.36, GOC:pz] +xref: EC:2.7.8.36 +xref: MetaCyc:RXN-13269 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups + +[Term] +id: GO:0102335 +name: N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+." [EC:2.4.1.290, GOC:pz] +xref: EC:2.4.1.290 +xref: MetaCyc:RXN-13274 +xref: RHEA:34511 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102336 +name: 3-oxo-arachidoyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A." [EC:2.3.1.199, GOC:pz] +xref: EC:2.3.1.199 +xref: MetaCyc:RXN-13294 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102337 +name: 3-oxo-cerotoyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A." [EC:2.3.1.199, GOC:pz] +xref: EC:2.3.1.199 +xref: MetaCyc:RXN-13296 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102338 +name: 3-oxo-lignoceronyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A." [EC:2.3.1.199, GOC:pz] +xref: EC:2.3.1.199 +xref: MetaCyc:RXN-13297 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102339 +name: 3-oxo-arachidoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+." [EC:1.1.1.330, GOC:pz] +xref: EC:1.1.1.330 +xref: MetaCyc:RXN-13298 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102340 +name: 3-oxo-behenoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+." [EC:1.1.1.330, GOC:pz] +xref: EC:1.1.1.330 +xref: MetaCyc:RXN-13299 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102341 +name: 3-oxo-lignoceroyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+." [EC:1.1.1.330, GOC:pz] +xref: EC:1.1.1.330 +xref: MetaCyc:RXN-13300 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102342 +name: 3-oxo-cerotoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+." [EC:1.1.1.330, GOC:pz] +xref: EC:1.1.1.330 +xref: MetaCyc:RXN-13301 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102343 +name: 3-hydroxy-arachidoyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA <=> trans-2-icosenoyl-CoA + H2O." [EC:4.2.1.134, GOC:pz] +xref: EC:4.2.1.134 +xref: MetaCyc:RXN-13302 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102344 +name: 3-hydroxy-behenoyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O." [EC:4.2.1.134, GOC:pz] +xref: EC:4.2.1.134 +xref: MetaCyc:RXN-13303 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102345 +name: 3-hydroxy-lignoceroyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O." [EC:4.2.1.134, GOC:pz] +xref: EC:4.2.1.134 +xref: MetaCyc:RXN-13304 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102346 +name: 3-hydroxy-cerotoyl-CoA dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA(4-) <=> trans-2-hexacosenoyl-CoA(4-) + H2O." [EC:4.2.1.134, GOC:pz] +xref: MetaCyc:RXN-13305 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102347 +name: trans-arachidon-2-enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: icosanoyl-CoA(4-) + NADP(3-) <=> trans-2-icosenoyl-CoA(4-) + NADPH(4-) + H+." [EC:1.3.1.93, GOC:pz] +xref: MetaCyc:RXN-13306 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102348 +name: trans-docosan-2-enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+." [EC:1.3.1.93, GOC:pz] +xref: MetaCyc:RXN-13307 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102349 +name: trans-lignocero-2-enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+." [EC:1.3.1.93, GOC:pz] +xref: MetaCyc:RXN-13308 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102350 +name: trans-cerot-2-enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+." [EC:1.3.1.93, GOC:pz] +xref: MetaCyc:RXN-13309 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102351 +name: gamma-aminobutyrate transaminase (glyoxylate dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine." [EC:2.6.1.96, GOC:pz] +xref: EC:2.6.1.96 +xref: MetaCyc:RXN-13328 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0102352 +name: phosphatidate kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate." [EC:2.7.4.-, GOC:pz] +xref: MetaCyc:RXN-13336 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0102353 +name: multiradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate <=> miltiradiene + diphosphoric acid." [EC:4.2.3.131, GOC:pz] +xref: EC:4.2.3.131 +xref: MetaCyc:RXN-13338 +xref: RHEA:33983 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102354 +name: 11-cis-retinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13363 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102355 +name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+." [EC:3.1.1.91, GOC:pz] +xref: EC:3.1.1.91 +xref: MetaCyc:RXN-13371 +xref: RHEA:33967 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102356 +name: isoitalicene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-13373 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102357 +name: mithramycin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13385 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102358 +name: daphnetin-8-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13448 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102359 +name: daphnetin 4-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+." [EC:2.4.1.126, GOC:pz] +xref: EC:2.4.1.126 +xref: MetaCyc:RXN-13450 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102360 +name: daphnetin 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+." [EC:2.4.1.91, GOC:pz] +xref: EC:2.4.1.91 +xref: MetaCyc:RXN-13452 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102361 +name: esculetin 4-O-beta-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+." [EC:2.4.1.126, GOC:pz] +xref: EC:2.4.1.126 +xref: MetaCyc:RXN-13471 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102362 +name: esculetin 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13472 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102363 +name: isoscopoletin-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13475 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102365 +name: taxusin 2-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13486 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102366 +name: 7-beta-hydroxytaxusin 2-alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13487 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102367 +name: 2-alpha-hydroxytaxusin 7-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13488 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102368 +name: beta-amyrin 30-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13489 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102369 +name: 11alpha-30-dihydroxy beta-amyrin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-13491 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102370 +name: lupeol 28-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13497 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102371 +name: betulin dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-13498 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102372 +name: alpha-amyrin 28-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13500 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102373 +name: uvaol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-13501 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102374 +name: ursolic aldehyde 28-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13502 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102375 +name: 11-oxo-beta-amyrin 30-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O." [EC:1.14.14.115, GOC:pz] +xref: EC:1.14.14.115 +xref: MetaCyc:RXN-13506 +xref: RHEA:35499 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102376 +name: lupeol 28-oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13507 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102377 +name: steviol 13-O glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13511 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102378 +name: steviolmonoside glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13512 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102379 +name: steviolbioside glucosyltransferase activity (stevioside forming) +namespace: molecular_function +def: "Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13514 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102380 +name: steviolbioside glucosyltransferase activity (rebaudioside B forming) +namespace: molecular_function +def: "Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13516 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102381 +name: stevioside glucosyltransferase activity (rebaudioside A forming) +namespace: molecular_function +def: "Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13517 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102382 +name: rebaudioside B glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13518 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102383 +name: steviol 19-O glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13520 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102384 +name: 19-O-beta-glucopyranosyl-steviol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13521 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102385 +name: patchoulol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-13522 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102386 +name: phenylacetaldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13536 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102387 +name: 2-phenylethanol acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A." [EC:2.3.1.224, GOC:pz] +xref: EC:2.3.1.224 +xref: MetaCyc:RXN-13542 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102388 +name: UDP-N,N'-diacetylbacillosamine 2-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+." [EC:3.2.1.184, GOC:pz] +xref: EC:3.2.1.184 +xref: MetaCyc:RXN-13574 +xref: RHEA:34491 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102389 +name: polyprenol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol." [EC:1.3.1.94, GOC:pz] +xref: EC:1.3.1.94 +xref: MetaCyc:RXN-13604 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102390 +name: mycophenolic acid acyl-glucuronide esterase activity +namespace: molecular_function +def: "Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate." [EC:3.1.1.93, GOC:pz] +xref: EC:3.1.1.93 +xref: MetaCyc:RXN-13605 +xref: RHEA:34179 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102391 +name: decanoate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: decanoate + ATP(4-) + coenzyme A(4-) <=> decanoyl-CoA(4-) + AMP(2-) + diphosphoric acid." [EC:6.2.1.3, GOC:pz] +xref: EC:6.2.1.3 +xref: MetaCyc:RXN-13614 +is_a: GO:0031956 ! medium-chain fatty acid-CoA ligase activity + +[Term] +id: GO:0102392 +name: decanoate-[HmqF protein] ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN-13623 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0102393 +name: decanoyl-[acp] 2-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF." [EC:1.3.8.-, GOC:pz] +xref: MetaCyc:RXN-13624 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102394 +name: 4-hydroxy-L-isoleucine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13637 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102395 +name: 9-cis-beta-carotene 9',10'-cleavage oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone." [EC:1.13.11.68, GOC:pz] +xref: EC:1.13.11.68 +xref: MetaCyc:RXN-13642 +xref: RHEA:34399 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102396 +name: 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal." [EC:1.13.11.69, GOC:pz] +xref: EC:1.13.11.69 +xref: MetaCyc:RXN-13643 +xref: RHEA:34403 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102398 +name: dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13657 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102399 +name: dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13658 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102400 +name: dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13667 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102402 +name: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose." [EC:3.2.1.149, GOC:pz] +xref: EC:3.2.1.149 +xref: MetaCyc:RXN-13694 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102404 +name: linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity +namespace: molecular_function +def: "Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool." [EC:3.2.1.149, GOC:pz] +xref: EC:3.2.1.149 +xref: MetaCyc:RXN-13701 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102405 +name: (+)-taxifolin 5'-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13718 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102406 +name: omega-hydroxypalmitate O-sinapoyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate." [EC:2.3.1.188, GOC:pz] +xref: EC:2.3.1.188 +xref: MetaCyc:RXN-13728 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102407 +name: sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: C22:0-DCA-CoA + sn-glycerol 3-phosphate <=> coenzyme A + 2-C22:0-DCA-LPA." [EC:2.3.1.198, GOC:pz] +xref: MetaCyc:RXN-13734 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102408 +name: sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate <=> coenzyme A + sn-2-C16:0-DCA-LPA." [EC:2.3.1.198, GOC:pz] +xref: MetaCyc:RXN-13735 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102409 +name: sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: behenoyl-CoA + sn-glycerol 3-phosphate(2-) <=> coenzyme A + 2-docosanoyl-glycerol 3-phosphate." [EC:2.3.1.198, GOC:pz] +xref: MetaCyc:RXN-13736 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102410 +name: quercetin-4',3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-)." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13765 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102411 +name: quercetin-3,4'-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-)." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13766 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102412 +name: valerena-4,7(11)-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid." [EC:4.2.3.139, GOC:pz] +xref: EC:4.2.3.139 +xref: MetaCyc:RXN-13769 +xref: RHEA:34467 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102413 +name: 6-O-methyl-deacetylisoipecoside beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-13791 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102414 +name: quercetin-3-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13797 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102415 +name: quercetin gentiobioside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13798 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102416 +name: quercetin gentiotrioside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13799 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102417 +name: apigenin-7-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13800 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102418 +name: luteolin-7-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13801 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102419 +name: sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA." [EC:2.3.1.198, GOC:pz] +xref: EC:2.3.1.198 +xref: MetaCyc:RXN-13803 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102420 +name: sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate." [EC:2.3.1.15, GOC:pz] +xref: EC:2.3.1.15 +xref: MetaCyc:RXN-13805 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102421 +name: curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13813 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102422 +name: curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13814 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102423 +name: (+)-sesaminol 2-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13818 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102424 +name: sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13821 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102425 +name: myricetin 3-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP." [EC:2.4.1.91, GOC:pz] +xref: EC:2.4.1.91 +xref: MetaCyc:RXN-13822 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102426 +name: myricetin-3-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13823 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102427 +name: allocryptopine 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-13828 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102428 +name: kaempferol-3-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13830 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102429 +name: genistein-3-O-glucoside 1,6-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-13831 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102430 +name: alpha-linolenate Delta5 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-13857 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102431 +name: linoleate Delta5 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O2 + a reduced electron acceptor = pinolenate + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-13858 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102432 +name: quercetin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13906 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102433 +name: phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine + a 10-formyltetrahydrofolate-4a-carbinolamine." [EC:1.14.16.1, GOC:pz] +xref: MetaCyc:RXN-13907 +is_a: GO:0016714 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102434 +name: pterin-4alpha-carbinolamine dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate." [GOC:pz, PMID:18245455, PMID:20959559] +xref: MetaCyc:RXN-13908 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102435 +name: myricetin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13910 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102436 +name: 7-methylmyricetin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13911 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102438 +name: laricitrin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13914 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102439 +name: 3',4',5'-trimethylmyricetin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13916 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102440 +name: 3',4',5'-trimethylmyricetin 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13918 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102441 +name: syringetin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13919 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102442 +name: syringetin 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13920 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102443 +name: L-2-hydroxycarboxylate dehydrogenase (NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate." [EC:1.1.1.337, GOC:pz] +xref: EC:1.1.1.337 +xref: MetaCyc:RXN-13927 +xref: RHEA:34555 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102444 +name: isorhamnetin 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13929 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102445 +name: 3-methylquercetin 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13930 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102446 +name: rhamnetin 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13932 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102447 +name: rhamnetin 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13933 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102448 +name: rhamnetin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> ombuin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13934 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102449 +name: kaempferol 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13935 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102450 +name: kaempferide 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13936 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102451 +name: kaempferide 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-13937 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102452 +name: bisdemethoxycurcumin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide." [EC:2.3.1.211, GOC:pz] +xref: EC:2.3.1.211 +xref: MetaCyc:RXN-13958 +xref: RHEA:34803 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102453 +name: anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside]." [GOC:pz, RHEA:35411] +xref: EC:2.3.1.215 +xref: MetaCyc:RXN-13959 +xref: RHEA:35411 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102454 +name: cyanidin 3-O-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP." [GOC:pz, RHEA:35631] +xref: EC:2.4.1.294 +xref: MetaCyc:RXN-13960 +xref: RHEA:35631 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102455 +name: anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside." [GOC:pz, RHEA:35419] +xref: EC:2.4.1.297 +xref: MetaCyc:RXN-13965 +xref: RHEA:35419 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102456 +name: cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+." [EC:2.4.1.299, GOC:pz] +xref: MetaCyc:RXN-13967 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102457 +name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate." [EC:2.4.1.300, GOC:pz] +xref: EC:2.4.1.300 +xref: MetaCyc:RXN-13969 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102458 +name: cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+." [EC:2.4.1.299, GOC:pz] +xref: EC:2.4.1.299 +xref: MetaCyc:RXN-13970 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102459 +name: 8-oxo-deoxyadenine diphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+." [EC:3.6.1.-, GOC:pz] +xref: MetaCyc:RXN-14005 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102460 +name: kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14008 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102461 +name: kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14009 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102462 +name: quercetin 3-sophoroside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14011 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102463 +name: quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14012 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102464 +name: zeaxanthin 2-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14016 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102465 +name: zeaxanthin 2,2'-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14018 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102466 +name: beta-carotene 2,2'-beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14019 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102467 +name: scutellarein 7-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+." [EC:2.4.1.253, GOC:pz] +xref: EC:2.4.1.253 +xref: MetaCyc:RXN-14058 +xref: RHEA:28318 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102468 +name: wogonin 7-O-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+." [EC:2.4.1.253, GOC:pz] +xref: EC:2.4.1.253 +xref: MetaCyc:RXN-14060 +xref: RHEA:28322 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102469 +name: naringenin 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14069 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102470 +name: 6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14075 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102471 +name: 2-hydroxynaringenin-6C-glucoside dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-14076 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102472 +name: eriodictyol 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14077 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102473 +name: eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14079 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102474 +name: eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14080 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102475 +name: 2-hydroxyeriodictyol 6C-glucoside dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-14081 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102476 +name: pinocembrin 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14083 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102477 +name: 2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-14088 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102478 +name: beta-L-arabinofuranosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose." [GOC:pz, RHEA:36051] +xref: EC:3.2.1.185 +xref: MetaCyc:RXN-14089 +xref: RHEA:36051 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102479 +name: quercetin 3-O-beta:-D-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+." [EC:2.4.1.234, GOC:pz] +xref: EC:2.4.1.234 +xref: MetaCyc:RXN-14109 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102480 +name: 5-fluorocytosine deaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium." [EC:3.5.4.1, GOC:pz] +xref: EC:3.5.4.1 +xref: MetaCyc:RXN-14129 +is_a: GO:0016814 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + +[Term] +id: GO:0102481 +name: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+." [EC:3.7.1.22, GOC:pz] +xref: EC:3.7.1.22 +xref: MetaCyc:RXN-14149 +xref: RHEA:25836 +is_a: GO:0016823 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances + +[Term] +id: GO:0102482 +name: 5-deoxy-D-glucuronate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate." [GOC:pz, RHEA:25840] +xref: EC:5.3.1.30 +xref: MetaCyc:RXN-14150 +xref: RHEA:25840 +is_a: GO:0016861 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses + +[Term] +id: GO:0102483 +name: scopolin beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin." [EC:3.2.1.21, GOC:pz] +xref: EC:3.2.1.21 +xref: MetaCyc:RXN-14179 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102484 +name: esculetin glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14182 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102485 +name: dATP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14195 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102486 +name: dCTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14198 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102487 +name: dUTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14199 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102488 +name: dTTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14200 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102489 +name: GTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14201 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102490 +name: 8-oxo-dGTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14205 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102491 +name: dGTP phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+." [EC:3.6.1.5, GOC:pz] +xref: EC:3.6.1.5 +xref: MetaCyc:RXN-14208 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0102493 +name: wogonin 7-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14239 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102494 +name: GA20 2,3-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-14317 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102495 +name: GA5 3beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-14318 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102496 +name: GA5 2,3 epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-14327 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102497 +name: scyllo-inositol dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+." [EC:1.1.1.371, GOC:pz] +xref: EC:1.1.1.371 +xref: MetaCyc:RXN-14347 +xref: RHEA:39063 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102498 +name: maltose glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + maltose = 2 glucose." [GOC:pz, PMID:16343940] +xref: MetaCyc:RXN-15910 +is_a: GO:0090599 ! alpha-glucosidase activity + +[Term] +id: GO:0102499 +name: SHG alpha-glucan phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan." [GOC:pz, RHEA:41732] +xref: EC:2.4.1.1 +xref: MetaCyc:RXN-14353 +xref: RHEA:41732 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102500 +name: beta-maltose 4-alpha-glucanotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose." [EC:2.4.1.25, GOC:pz] +xref: EC:2.4.1.25 +xref: MetaCyc:RXN-14354 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102501 +name: D-fructuronate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14368 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102502 +name: ADP-glucose-starch glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose." [EC:2.4.1.242, GOC:pz] +xref: EC:2.4.1.242 +xref: MetaCyc:RXN-14378 +is_a: GO:0033840 ! NDP-glucose-starch glucosyltransferase activity + +[Term] +id: GO:0102504 +name: luteolinidin 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14424 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102505 +name: apigeninidin 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-14427 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102506 +name: cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+." [EC:2.4.1.299, GOC:pz] +xref: EC:2.4.1.299 +xref: MetaCyc:RXN-14432 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102507 +name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+." [EC:2.4.1.300, GOC:pz] +xref: EC:2.4.1.300 +xref: MetaCyc:RXN-14434 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102508 +name: cyanidin 3,7-diglucoside glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-14435 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102509 +name: cyanidin 3,5-diglucoside glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-14436 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102510 +name: pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+." [EC:2.4.1.299, GOC:pz] +xref: EC:2.4.1.299 +xref: MetaCyc:RXN-14439 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102511 +name: pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+." [EC:2.4.1.300, GOC:pz] +xref: EC:2.4.1.300 +xref: MetaCyc:RXN-14440 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102512 +name: delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+." [EC:2.4.1.299, GOC:pz] +xref: EC:2.4.1.299 +xref: MetaCyc:RXN-14441 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102513 +name: delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+." [EC:2.4.1.300, GOC:pz] +xref: MetaCyc:RXN-14442 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102514 +name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+." [EC:2.4.1.300, GOC:pz] +xref: EC:2.4.1.300 +xref: MetaCyc:RXN-14446 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102515 +name: pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+." [EC:2.4.1.300, GOC:pz] +xref: MetaCyc:RXN-14447 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102516 +name: delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+." [EC:2.4.1.300, GOC:pz] +xref: MetaCyc:RXN-14448 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102517 +name: oleate 12-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14487 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102518 +name: (11Z)-eicosenoate 14-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14488 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102520 +name: L-threonine O-3-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-14505 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102521 +name: tRNA-4-demethylwyosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe." [GOC:pz, RHEA:36347] +xref: EC:4.1.3.44 +xref: MetaCyc:RXN-14516 +xref: RHEA:36347 +is_a: GO:0016833 ! oxo-acid-lyase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0102522 +name: tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe." [EC:2.5.1.114, GOC:pz] +xref: EC:2.5.1.114 +xref: MetaCyc:RXN-14518 +xref: RHEA:36355 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0102523 +name: 2-chloroacrylate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+." [EC:1.3.1.103, GOC:pz] +xref: EC:1.3.1.103 +xref: MetaCyc:RXN-14536 +xref: RHEA:36591 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102524 +name: tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe." [GOC:pz, RHEA:37899] +xref: EC:1.14.11.42 +xref: MetaCyc:RXN-14538 +xref: RHEA:37899 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA + +[Term] +id: GO:0102525 +name: 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide." [GOC:pz, RHEA:36607] +xref: EC:1.14.11.41 +xref: MetaCyc:RXN-14542 +xref: RHEA:36607 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102526 +name: 8-demethylnovobiocic acid C8-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine + novobiocic acid + H+." [EC:2.1.1.284, GOC:pz] +xref: EC:2.1.1.284 +xref: MetaCyc:RXN-14543 +xref: RHEA:36651 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102527 +name: 8-demethylnovobiocate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid." [EC:6.3.1.15, GOC:pz] +xref: EC:6.3.1.15 +xref: MetaCyc:RXN-14547 +xref: RHEA:36699 +is_a: GO:0016880 ! acid-ammonia (or amide) ligase activity + +[Term] +id: GO:0102528 +name: 7,8,4'-trihydroxyflavone methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14658 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102529 +name: apigenin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + apigenin-7-olate <=> S-adenosyl-L-homocysteine + genkwanin." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14661 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102530 +name: aclacinomycin T methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T + methanol + H+." [EC:3.1.1.95, GOC:pz] +xref: EC:3.1.1.95 +xref: MetaCyc:RXN-14703 +xref: RHEA:37891 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102531 +name: ecdysteroid-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate <=> hydrogenphosphate + an ecdysteroid." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-14734 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102532 +name: genkwanin 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14748 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102533 +name: genkwanin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14750 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102534 +name: apigenin-7,4'-dimethyl ether 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14751 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102535 +name: ladanein 6-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: ladanein + S-adenosyl-L-methionine <=> H+ + salvigenin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14752 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102536 +name: sakuranetin 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-14754 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102537 +name: ecdysone-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-14766 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102538 +name: UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14767 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102539 +name: UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-14769 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102540 +name: D-mannose 6-phosphate 1-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate." [EC:5.1.3.-, GOC:pz] +xref: MetaCyc:RXN-14815 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0102541 +name: D-galactose 6-phosphate 1-epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate." [EC:5.1.3.-, GOC:pz] +xref: MetaCyc:RXN-14816 +is_a: GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives + +[Term] +id: GO:0102542 +name: aclacinomycin A methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+." [EC:3.1.1.95, GOC:pz] +xref: EC:3.1.1.95 +xref: MetaCyc:RXN-14863 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102543 +name: epsilon-rhodomycinone methylesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+." [EC:3.1.1.95, GOC:pz] +xref: EC:3.1.1.95 +xref: MetaCyc:RXN-14865 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102544 +name: ornaline synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O." [EC:1.5.1.-, GOC:pz] +xref: MetaCyc:RXN-14880 +is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102545 +name: phosphatidyl phospholipase B activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate." [EC:3.1.1.5, GOC:pz] +xref: EC:3.1.1.5 +xref: MetaCyc:RXN-14899 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102546 +name: mannosylglycerate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate." [EC:3.3.2.-, GOC:pz] +xref: MetaCyc:RXN-14900 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0102547 +name: glucosylglycerate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate." [EC:3.3.2.-, GOC:pz] +xref: MetaCyc:RXN-14901 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0102549 +name: 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+." [EC:3.1.1.26, GOC:pz] +xref: EC:3.1.1.26 +xref: MetaCyc:RXN-14912 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102550 +name: 2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+." [EC:2.1.1.295, GOC:pz] +xref: EC:2.1.1.295 +xref: MetaCyc:RXN-14917 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102551 +name: homogentisate geranylgeranyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide." [EC:2.5.1.116, GOC:pz] +xref: EC:2.5.1.116 +xref: MetaCyc:RXN-14929 +xref: RHEA:38003 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102552 +name: lipoyl synthase activity (acting on glycine-cleavage complex H protein +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]." [EC:2.8.1.8, GOC:pz] +xref: EC:2.8.1.8 +xref: MetaCyc:RXN-14950 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0102553 +name: lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein) +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]." [EC:2.8.1.8, GOC:pz] +xref: EC:2.8.1.8 +xref: MetaCyc:RXN-14957 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0102554 +name: lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]." [EC:2.8.1.8, GOC:pz] +xref: MetaCyc:RXN-14959 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0102555 +name: octanoyl transferase activity (acting on glycine-cleavage complex H protein) +namespace: molecular_function +def: "Catalysis of the reaction: [glycine cleavage system lipoyl-carrier protein]-L-lysine + octanoyl-ACP = H+ + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein]." [GOC:pz, RHEA:17665] +xref: EC:2.3.1.181 +xref: MetaCyc:RXN-14966 +xref: RHEA:17665 +is_a: GO:0016415 ! octanoyltransferase activity + +[Term] +id: GO:0102556 +name: dammarenediol 12-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O." [EC:1.14.14.120, GOC:pz] +xref: EC:1.14.14.120 +xref: MetaCyc:RXN-14975 +xref: RHEA:38579 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102557 +name: protopanaxadiol 6-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O." [EC:1.14.14.121, GOC:pz] +xref: EC:1.14.14.121 +xref: MetaCyc:RXN-14978 +xref: RHEA:22272 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102559 +name: protein-(glutamine-N5) methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine." [GOC:pz, RHEA:42896] +xref: EC:2.1.1.297 +xref: MetaCyc:RXN-14992 +xref: RHEA:42896 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102560 +name: 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+." [EC:3.1.4.57, GOC:pz] +synonym: "phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase" EXACT [] +xref: EC:3.1.4.57 +xref: MetaCyc:RXN-14995 +xref: RHEA:41612 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0102561 +name: D-ribose 2,5-bisphosphate 2-phosphohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate." [EC:3.1.4.57, GOC:pz] +xref: EC:3.1.4.57 +xref: MetaCyc:RXN-14996 +xref: RHEA:41617 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0102562 +name: hydroxyproline O-arbinofuranose transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline." [EC:2.4.2.-, GOC:pz] +xref: MetaCyc:RXN-15011 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0102563 +name: aurachin C monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15029 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102564 +name: aurachin C epoxide hydrolase/isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P)." [EC:3.3.2.-, GOC:pz] +xref: MetaCyc:RXN-15030 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0102566 +name: 1-acyl dihydroxyacetone phosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP." [EC:1.1.1.101, GOC:pz] +xref: EC:1.1.1.101 +xref: MetaCyc:RXN-15046 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102567 +name: phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) +namespace: molecular_function +def: "Catalysis of the reaction: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+." [EC:3.1.1.4, GOC:pz] +xref: EC:3.1.1.4 +xref: MetaCyc:RXN-15065 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102568 +name: phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:1-phosphatidylethanolamine + H2O = 1-oleoyl-sn-glycero-3-phosphoethanolamine + oleate + H+." [EC:3.1.1.4, GOC:pz] +xref: EC:3.1.1.4 +xref: MetaCyc:RXN-15067 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102569 +name: FR-33289 synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-15082 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102570 +name: tyrosine:phenylpyruvate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine = L-phenylalanine + 3-(4-hydroxyphenyl)pyruvate." [EC:2.6.1.-, GOC:pz] +xref: MetaCyc:RXN-15200 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0102571 +name: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine)." [EC:3.2.1.169, GOC:pz] +xref: EC:3.2.1.169 +xref: MetaCyc:RXN-15215 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102572 +name: N-glutamylanilide hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+." [EC:3.5.1.-, GOC:pz] +xref: MetaCyc:RXN-15251 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0102573 +name: aminodeoxyfutalosine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O <=> aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+." [EC:2.5.1.120, GOC:pz] +xref: EC:2.5.1.120 +xref: MetaCyc:RXN-15264 +xref: RHEA:33075 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102574 +name: 3-oxo-myristoyl-ACP hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein]." [EC:3.1.2.-, GOC:pz] +xref: MetaCyc:RXN-15280 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102575 +name: 3-oxo-dodecanoyl-ACP hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein]." [EC:3.1.2.-, GOC:pz] +xref: MetaCyc:RXN-15281 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102576 +name: 3-oxo-palmitoyl-ACP hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein]." [EC:3.1.2.-, GOC:pz] +xref: MetaCyc:RXN-15282 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102577 +name: 3-oxo-palmitate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide." [EC:4.1.1.56, GOC:pz] +xref: EC:4.1.1.56 +xref: MetaCyc:RXN-15283 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0102580 +name: cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP." [EC:2.4.2.51, GOC:pz] +xref: EC:2.4.2.51 +xref: MetaCyc:RXN-15326 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0102581 +name: cyanidin 3-O-glucoside-p-coumaroyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15327 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102582 +name: cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+." [EC:2.4.2.-, GOC:pz] +xref: MetaCyc:RXN-15328 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0102583 +name: cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15329 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102584 +name: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15330 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102585 +name: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15331 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102586 +name: cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15332 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102587 +name: cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15333 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102588 +name: cyanidin 3-O-glucoside 6''-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A." [EC:2.3.1.171, GOC:pz] +xref: EC:2.3.1.171 +xref: MetaCyc:RXN-15335 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102589 +name: cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15336 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102590 +name: delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15351 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102591 +name: delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15352 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102592 +name: delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15354 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102593 +name: UDP-glucose: N-methylanthranilate glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15371 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102594 +name: cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15372 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102595 +name: cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15374 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102596 +name: cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O." [EC:1.14.14.70, GOC:pz] +xref: EC:1.14.14.70 +xref: MetaCyc:RXN-15379 +xref: RHEA:41464 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102597 +name: 3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O." [EC:1.14.14.122, GOC:pz] +xref: EC:1.14.14.122 +xref: MetaCyc:RXN-15381 +xref: RHEA:41468 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102598 +name: 3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O." [EC:1.14.14.123, GOC:pz] +xref: EC:1.14.14.123 +xref: MetaCyc:RXN-15382 +xref: RHEA:41472 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102599 +name: cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15383 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102600 +name: cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15384 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102601 +name: cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 16beta-hydroxy-beta-amyrin + H2O + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15385 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102602 +name: cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15386 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102603 +name: 12-demethyl-elloramycin C12a O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine <=> elloramycin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15402 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102604 +name: naringenin,NADPH:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O." [EC:1.14.14.87, GOC:pz] +xref: EC:1.14.14.87 +xref: MetaCyc:RXN-1541 +xref: RHEA:35487 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102605 +name: cyclooctat-9-en-5,7-diol C18-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15430 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102606 +name: octat-9-en-7-ol 5-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15431 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102607 +name: 3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15433 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102608 +name: tetracenomycin B3 8-O-methyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine <=> tetracenomycin E + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15435 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102609 +name: 9-beta-stemod-13(17)-ene oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: stemod-13(17)-ene + 3 NADPH + 3 O2 + 3 H+ <=> 9beta-stemod-13(17)-en-19-oate + 3 NADP + 4 H2O." [EC:1.14.13.144, GOC:pz] +xref: EC:1.14.13.144 +xref: MetaCyc:RXN-15437 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102610 +name: (+)-secoisolariciresinol glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15442 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102611 +name: (+)-secoisolariciresinol monoglucoside glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-15443 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102612 +name: syn-pimaradiene 6beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15452 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102613 +name: trimethyluric acid monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15454 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102614 +name: germacrene A acid 8beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15460 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102615 +name: ent-cassadiene-C2-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15462 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102616 +name: oryzalexin A synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15464 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102617 +name: oryzalexin C synthase (oryzalexin B dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: oryzalexin B + NAD(P) <=> oryzalexin C + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15465 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102618 +name: oryzalexin B synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15466 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102619 +name: oryzalexin C synthase (oryzalexin A dependent) activity +namespace: molecular_function +def: "Catalysis of the reaction: oryzalexin A + NAD(P) <=> oryzalexin C + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15467 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102620 +name: 3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15495 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102621 +name: emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity +namespace: molecular_function +def: "Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15496 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102622 +name: linuron hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline." [EC:3.5.1.-, GOC:pz] +xref: MetaCyc:RXN-15526 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0102623 +name: scutellarein 7-methyl ether 6-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15528 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102624 +name: scutellarein 7-methyl ether 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> ladanein + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15529 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102625 +name: cirsimaritin 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15530 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102626 +name: parthenolide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15531 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102627 +name: parthenolide 3beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15532 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102628 +name: costunolide 3beta-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15533 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102629 +name: patuletin 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: patuletin + S-adenosyl-L-methionine <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15534 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102630 +name: gossypetin 8-methyl ester 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15536 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102631 +name: caffeoylglucose 3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15537 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102632 +name: (S)-nandinine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-scoulerine + NADPH + H+ + O2 <=> (S)-nandinine + NADP + 2 H2O." [GOC:pz] +xref: MetaCyc:RXN-15538 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0102633 +name: flaviolin monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15585 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102634 +name: 1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+." [EC:1.13.12.-, GOC:pz] +xref: MetaCyc:RXN-15586 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0102635 +name: 11-deoxycorticosterone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15607 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102636 +name: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine gamma-glutamylcyclotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine <=> 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine + 2 5-oxo-L-prolinate." [EC:2.3.2.-, GOC:pz] +xref: MetaCyc:RXN-15681 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0102637 +name: 5-aminolevulinate-CoA ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15714 +is_a: GO:0016405 ! CoA-ligase activity +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0102638 +name: [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid." [EC:2.5.1.105, GOC:pz] +xref: EC:2.5.1.105 +xref: MetaCyc:RXN-15734 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102639 +name: paspalicine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15737 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102640 +name: paspalinine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-15738 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102641 +name: (R)-lactaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-15743 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102643 +name: scalarane-17alpha-19-diol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15755 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102644 +name: monocyclic sesterterpenediol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15756 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102645 +name: 17(E)-cheilanthenediol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15758 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102646 +name: 14betaH-scalarane-17alpha-19-diol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O." [EC:4.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15759 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102647 +name: D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate." [EC:2.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15789 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0102648 +name: D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate." [EC:2.2.1.-, GOC:pz] +xref: MetaCyc:RXN-15790 +is_a: GO:0016744 ! transferase activity, transferring aldehyde or ketonic groups + +[Term] +id: GO:0102649 +name: acetoacetyl-ACP synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-15810 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102650 +name: cyclo-acetoacetyl-L-tryptophan synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein]." [EC:6.3.2.-, GOC:pz] +xref: MetaCyc:RXN-15811 +is_a: GO:0016881 ! acid-amino acid ligase activity + +[Term] +id: GO:0102652 +name: gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-171 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102653 +name: gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-172 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102654 +name: 1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-1725 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102655 +name: 1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-1726 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102656 +name: 1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-1727 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102657 +name: 1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-1728 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102658 +name: 2-oxo-5-methylthiopentanoate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate." [EC:2.6.1.-, GOC:pz] +xref: MetaCyc:RXN-2205 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0102659 +name: UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXN-2208 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102660 +name: caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-2621 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102661 +name: homogentisate solanyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid." [EC:2.5.1.117, GOC:pz] +xref: EC:2.5.1.117 +xref: MetaCyc:RXN-2761 +xref: RHEA:37995 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102662 +name: malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-oxopropanoate + coenzyme A(4-) + NAD(1-) <=> acetyl-CoA(4-) + carbon dioxide + NADH(2-)." [EC:1.2.1.-, GOC:pz] +xref: MetaCyc:RXN-2902 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102663 +name: gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-292 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102664 +name: indole-3-acetyl-leucine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-leucine + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-2945 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102665 +name: indole-3-acetyl-glutamate synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-2947 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102666 +name: indole-3-acetyl-beta-4-D-glucose hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose." [EC:3.1.-.-, GOC:pz] +xref: MetaCyc:RXN-3164 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0102667 +name: indole-3-acetyl-beta-1-D-glucose hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose." [EC:3.1.-.-, GOC:pz] +xref: MetaCyc:RXN-3165 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds + +[Term] +id: GO:0102668 +name: liquiritigenin,NADPH:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O." [EC:1.14.14.87, GOC:pz] +xref: EC:1.14.14.87 +xref: MetaCyc:RXN-3283 +xref: RHEA:31723 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102669 +name: isoflavone-7-O-glucoside beta-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-3591 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102670 +name: 2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine." [EC:2.1.1.212, GOC:pz] +xref: EC:2.1.1.212 +xref: MetaCyc:RXN-3624 +xref: RHEA:31371 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102671 +name: 6a-hydroxymaackiain-3-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine." [EC:2.1.1.270, GOC:pz] +xref: EC:2.1.1.270 +xref: MetaCyc:RXN-4002 +xref: RHEA:35471 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102672 +name: fatty acid alpha-oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid." [EC:1.13.11.-, GOC:pz] +xref: MetaCyc:RXN-4121 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102673 +name: fatty aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid." [EC:1.2.1.3, GOC:pz] +xref: MetaCyc:RXN-4142 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102674 +name: C4-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-methylenelophenol + a demethylated methyl acceptor <=> 9xi-episterol + a methylated methyl acceptor." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-4181 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102675 +name: C4-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-ethylidenelophenol + a demethylated methyl acceptor <=> avenasterol + a methylated methyl acceptor." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-4208 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102676 +name: avenasterol-desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-4209 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102677 +name: campesterol,NADPH:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-4225 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102678 +name: 22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-4229 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102679 +name: (5alpha)-campestan-3-one hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-4230 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102680 +name: campest-4-en-3-one hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-4231 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102681 +name: isoamylase (maltodextrin-releasing) activity +namespace: molecular_function +def: "Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin." [EC:3.2.1.68, GOC:pz] +xref: MetaCyc:RXN-4301 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102682 +name: N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate." [EC:3.2.2.-, GOC:pz] +xref: MetaCyc:RXN-4313 +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds + +[Term] +id: GO:0102684 +name: L-phenylalanine N-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide." [EC:1.14.14.40, GOC:pz] +xref: EC:1.14.14.40 +xref: MetaCyc:RXN-4602 +xref: RHEA:33263 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102685 +name: UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4721 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102686 +name: UDP-glucose:trans-zeatin 9-N-glucosyltransferase +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-)." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4722 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102687 +name: UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4724 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102688 +name: dihydrozeatin UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4725 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102689 +name: UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4727 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102690 +name: isopentenyladenine UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4728 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102691 +name: UDP-glucose:benzyladenine 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4729 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102692 +name: benzyladenine UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4730 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102693 +name: UDP-glucose:kinetin 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4731 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102694 +name: kinetin UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4732 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102695 +name: UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4733 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102696 +name: cis-zeatin UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4734 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102697 +name: trans-zeatin-O-glucoside UDP glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-4736 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102698 +name: 5-epi-aristolochene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid." [EC:4.2.3.61, GOC:pz] +xref: EC:4.2.3.61 +xref: MetaCyc:RXN-4781 +xref: RHEA:28635 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102699 +name: 2-methylpropionitrile hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-5082 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102700 +name: alpha-thujene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-5105 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102701 +name: tricyclene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid." [EC:4.2.3.105, GOC:pz] +xref: EC:4.2.3.105 +xref: MetaCyc:RXN-5121 +xref: RHEA:32687 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102702 +name: 2-carene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-5122 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102703 +name: camphene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid." [EC:4.2.3.117, GOC:pz] +xref: EC:4.2.3.117 +xref: MetaCyc:RXN-5142 +xref: RHEA:25484 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102704 +name: GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol." [EC:2.4.1.257, GOC:pz] +xref: EC:2.4.1.257 +xref: MetaCyc:RXN-5463 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102705 +name: serine decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + L-serine <=> ethanolaminium(1+) + carbon dioxide." [EC:4.1.1.-, GOC:pz] +xref: MetaCyc:RXN-5641 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0102706 +name: butein:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+." [GOC:pz, RHEA:34203] +xref: EC:1.21.3.6 +xref: MetaCyc:RXN-6242 +xref: RHEA:34203 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0102707 +name: S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine." [EC:2.1.1.49, GOC:pz] +xref: EC:2.1.1.49 +xref: MetaCyc:RXN-6461 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0102708 +name: S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-6462 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0102709 +name: S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-6464 +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity + +[Term] +id: GO:0102710 +name: D-inositol-3-phosphate glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+." [GOC:pz, RHEA:26188] +xref: EC:2.4.1.250 +xref: MetaCyc:RXN-6501 +xref: RHEA:26188 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102711 +name: gibberellin A25,oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6541 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102712 +name: gibberellin A13,oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6542 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102713 +name: gibberellin A25 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6543 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102714 +name: gibberellin A12,oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6544 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102715 +name: gibberellin A17,oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6546 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102716 +name: gibberellin A28,oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-6547 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102717 +name: DIBOA-glucoside oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide." [EC:1.14.11.59, GOC:pz] +xref: EC:1.14.11.59 +xref: MetaCyc:RXN-6685 +xref: RHEA:32115 +is_a: GO:0050498 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated + +[Term] +id: GO:0102718 +name: TRIBOA-glucoside methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.241, GOC:pz] +xref: EC:2.1.1.241 +xref: MetaCyc:RXN-6687 +xref: RHEA:32099 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102719 +name: S-adenosyl-L-methionine:eugenol-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine." [EC:2.1.1.146, GOC:pz] +xref: EC:2.1.1.146 +xref: MetaCyc:RXN-6741 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102720 +name: acetyl-coenzyme A:acetyl alcohol acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A." [EC:2.3.1.224, GOC:pz] +xref: EC:2.3.1.224 +xref: MetaCyc:RXN-6762 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102721 +name: ubiquinol:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone." [GOC:pz, RHEA:30255] +xref: EC:1.10.3.11 +xref: MetaCyc:RXN-6883 +xref: RHEA:30255 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0102722 +name: gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-6903 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102723 +name: UDP-glucose:curcumin glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-7062 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102724 +name: UDP-glucose:curcumin monoglucoside glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-7063 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102725 +name: 24-methyldesmosterol reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP." [EC:1.3.-.-, GOC:pz] +xref: MetaCyc:RXN-708 +is_a: GO:0016627 ! oxidoreductase activity, acting on the CH-CH group of donors + +[Term] +id: GO:0102726 +name: DIMBOA glucoside beta-D-glucosidase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose." [EC:3.2.1.182, GOC:pz] +xref: EC:3.2.1.182 +xref: MetaCyc:RXN-7082 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102727 +name: 3beta-hydroxysteroid dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-710 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102728 +name: campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-711 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102729 +name: 6-oxocampestanol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-715 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102730 +name: cathasterone hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-716 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102731 +name: D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP." [EC:2.7.1.-, GOC:pz] +xref: MetaCyc:RXN-7185 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0102732 +name: myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP." [EC:2.7.1.140, GOC:pz] +xref: EC:2.7.1.140 +xref: MetaCyc:RXN-7186 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0102733 +name: typhasterol C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-719 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102734 +name: brassinolide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-720 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102735 +name: trihydroxybenzophenone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide." [GOC:pz, RHEA:35143] +xref: EC:2.3.1.220 +xref: MetaCyc:RXN-7481 +xref: RHEA:35143 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102737 +name: p-coumaroyltriacetic acid synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7577 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102738 +name: (gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-7589 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102739 +name: (gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-7591 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102740 +name: theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine." [EC:2.1.1.160, GOC:pz] +xref: EC:2.1.1.160 +xref: MetaCyc:RXN-7599 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102741 +name: paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine." [EC:2.1.1.160, GOC:pz] +xref: EC:2.1.1.160 +xref: MetaCyc:RXN-7601 +xref: RHEA:10280 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102742 +name: R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP." [EC:1.1.1.237, GOC:pz] +xref: EC:1.1.1.237 +xref: MetaCyc:RXN-7632 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102743 +name: eriodictyol,NADPH:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7653 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102744 +name: all-trans-geranyl-geranyl diphosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7658 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102745 +name: dihydrogeranylgeranyl-PP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7659 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102746 +name: tetrahydrogeranylgeranyl-PP reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7660 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102747 +name: chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid." [EC:2.5.1.-, GOC:pz] +xref: MetaCyc:RXN-7663 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102748 +name: geranylgeranyl-chlorophyll a reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7664 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102749 +name: dihydrogeranylgeranyl-chlorophyll a reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7665 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102750 +name: tetrahydrogeranylgeranyl-chlorophyll a reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7666 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102751 +name: UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+." [EC:2.4.1.186, GOC:pz] +xref: EC:2.4.1.186 +xref: MetaCyc:RXN-7667 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102752 +name: 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) +namespace: molecular_function +def: "Catalysis of the reaction: a glucosylated glycogenin = a glycogen." [EC:2.4.1.18, GOC:pz] +xref: EC:2.4.1.18 +xref: MetaCyc:RXN-7669 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102753 +name: chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid." [EC:2.5.1.-, GOC:pz] +xref: MetaCyc:RXN-7673 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102754 +name: chlorophyllide-b:phytyl-diphosphate phytyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid." [EC:2.5.1.-, GOC:pz] +xref: MetaCyc:RXN-7674 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102755 +name: gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-7680 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102756 +name: very-long-chain 3-ketoacyl-CoA synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA." [GOC:pz, RHEA:32727] +xref: EC:2.3.1.199 +xref: MetaCyc:RXN-7697 +xref: RHEA:32727 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102757 +name: NADPH phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN-7703 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0102758 +name: very-long-chain enoyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA." [EC:1.3.1.93, GOC:pz] +xref: EC:1.3.1.93 +xref: MetaCyc:RXN-7711 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102759 +name: campestanol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-773 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102760 +name: 6-deoxocathasterone hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-774 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102761 +name: eriodictyol 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-7753 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102762 +name: eriodictyol 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-7754 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102763 +name: phytyl-P kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate." [EC:2.7.4.-, GOC:pz] +xref: MetaCyc:RXN-7763 +is_a: GO:0016776 ! phosphotransferase activity, phosphate group as acceptor + +[Term] +id: GO:0102764 +name: 6-deoxotyphasterol C-23 hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor." [EC:1.14.-.-, GOC:pz] +xref: MetaCyc:RXN-777 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + +[Term] +id: GO:0102765 +name: UDP-D-apiose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide." [EC:4.1.1.-, GOC:pz] +xref: MetaCyc:RXN-7770 +is_a: GO:0016831 ! carboxy-lyase activity + +[Term] +id: GO:0102766 +name: naringenin 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine <=> sakuranetin + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.232, GOC:pz] +xref: EC:2.1.1.232 +xref: MetaCyc:RXN-7773 +xref: RHEA:31539 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102767 +name: flavanone 4'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine." [EC:2.1.1.231, GOC:pz] +xref: EC:2.1.1.231 +xref: MetaCyc:RXN-7777 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102768 +name: anthocyanidin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-7785 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102769 +name: dihydroceramide glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine." [EC:2.4.1.80, GOC:pz] +xref: EC:2.4.1.80 +xref: MetaCyc:RXN-7793 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102770 +name: inositol phosphorylceramide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol." [EC:2.7.1.-, GOC:pz] +xref: MetaCyc:RXN-7795 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0102771 +name: sphingolipid very long chain fatty acid alpha-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7796 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102772 +name: sphingolipid long-chain base 4-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P)." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7797 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102773 +name: dihydroceramide kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate." [EC:2.7.1.138, GOC:pz] +xref: EC:2.7.1.138 +xref: MetaCyc:RXN-7799 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0102774 +name: p-coumaroyltriacetic acid lactone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7822 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102775 +name: 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7826 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102776 +name: UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-7828 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102777 +name: caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-)." [EC:2.3.1.153, GOC:pz] +xref: EC:2.3.1.153 +xref: MetaCyc:RXN-7842 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102778 +name: Delta9-tetrahydrocannabinolate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide." [EC:1.21.3.7, GOC:pz] +xref: EC:1.21.3.7 +xref: MetaCyc:RXN-7854 +xref: RHEA:34143 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0102779 +name: cannabidiolate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide." [EC:1.21.3.8, GOC:pz] +xref: EC:1.21.3.8 +xref: MetaCyc:RXN-7855 +xref: RHEA:34411 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0102780 +name: sitosterol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7876 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102781 +name: isofucosterol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7877 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102782 +name: cholestanol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-7878 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102783 +name: beta-carotene oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial." [EC:1.13.11.-, GOC:pz] +xref: MetaCyc:RXN-7883 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102784 +name: lutein oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial." [EC:1.13.11.-, GOC:pz] +xref: MetaCyc:RXN-7884 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102785 +name: violaxanthin oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial." [EC:1.13.11.-, GOC:pz] +xref: MetaCyc:RXN-7886 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102786 +name: stearoyl-[acp] desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin." [EC:1.14.19.2, GOC:pz] +xref: EC:1.14.19.2 +xref: MetaCyc:RXN-7903 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102787 +name: caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7997 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102788 +name: 4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-7998 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102789 +name: UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8005 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102790 +name: cyanidin 5,3-O-glycosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8006 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102791 +name: sulfuretin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O." [EC:1.21.3.6, GOC:pz] +xref: EC:1.21.3.6 +xref: MetaCyc:RXN-8008 +is_a: GO:0046993 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor + +[Term] +id: GO:0102792 +name: sinapaldehyde:NAD(P)+ oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH." [EC:1.2.1.-, GOC:pz] +xref: MetaCyc:RXN-8014 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102793 +name: soyasapogenol B glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate." [EC:2.4.1.262, GOC:pz] +xref: EC:2.4.1.262 +xref: MetaCyc:RXN-8086 +xref: RHEA:31475 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102794 +name: cinnamaldehyde:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide." [EC:1.2.3.9, GOC:pz] +xref: EC:1.2.3.9 +xref: MetaCyc:RXN-8089 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0102795 +name: 1-naphthaldehyde:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide." [EC:1.2.3.9, GOC:pz] +xref: EC:1.2.3.9 +xref: MetaCyc:RXN-8090 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0102796 +name: protocatechualdehyde:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide." [EC:1.2.3.9, GOC:pz] +xref: EC:1.2.3.9 +xref: MetaCyc:RXN-8091 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0102797 +name: geranial:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranial + O2 + H2O = H+ + geranate + hydrogen peroxide." [EC:1.2.3.1, GOC:pz] +xref: EC:1.2.3.1 +xref: MetaCyc:RXN-8093 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0102798 +name: heptaldehyde:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: heptanal + O2 + H2O = H+ + heptanoate + hydrogen peroxide." [EC:1.2.3.1, GOC:pz] +xref: EC:1.2.3.1 +xref: MetaCyc:RXN-8094 +is_a: GO:0016623 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor + +[Term] +id: GO:0102799 +name: glucosinolate glucohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides." [EC:3.2.1.147, GOC:pz] +xref: EC:3.2.1.147 +xref: MetaCyc:RXN-8134 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102800 +name: caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8138 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102801 +name: anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A." [GOC:pz, RHEA:35515] +xref: EC:2.3.1.214 +xref: MetaCyc:RXN-8139 +xref: RHEA:35515 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102802 +name: thebaine 6-O-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide." [EC:1.14.11.31, GOC:pz] +xref: EC:1.14.11.31 +xref: MetaCyc:RXN-8147 +xref: RHEA:27477 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102803 +name: thebane O-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide." [EC:1.14.11.32, GOC:pz] +xref: EC:1.14.11.32 +xref: MetaCyc:RXN-8149 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102804 +name: oripavine 6-O-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide." [EC:1.14.11.31, GOC:pz] +xref: EC:1.14.11.31 +xref: MetaCyc:RXN-8151 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102805 +name: codeine O-demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide." [EC:1.14.11.32, GOC:pz] +xref: EC:1.14.11.32 +xref: MetaCyc:RXN-8152 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102806 +name: 4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8170 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102807 +name: cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8176 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102808 +name: pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8177 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102809 +name: delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8178 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102810 +name: glutarate-semialdehyde dehydrogenase (NADP+) activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+." [EC:1.2.1.-, GOC:pz] +xref: MetaCyc:RXN-8182 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102811 +name: geraniol 10-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O." [EC:1.14.14.83, GOC:pz] +xref: EC:1.14.14.83 +xref: MetaCyc:RXN-8197 +xref: RHEA:32495 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102812 +name: 4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8204 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102813 +name: UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8205 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102814 +name: caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8232 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102815 +name: caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A." [EC:2.3.1.153, GOC:pz] +xref: EC:2.3.1.153 +xref: MetaCyc:RXN-8233 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102816 +name: UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP." [EC:2.4.1.298, GOC:pz] +xref: EC:2.4.1.298 +xref: MetaCyc:RXN-8234 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102817 +name: caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8235 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102818 +name: lycopene cleavage oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde." [EC:1.13.12.-, GOC:pz] +xref: MetaCyc:RXN-8236 +is_a: GO:0016703 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) + +[Term] +id: GO:0102819 +name: bixin aldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+." [EC:1.2.1.-, GOC:pz] +xref: MetaCyc:RXN-8237 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102820 +name: norbixin methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: norbixin + S-adenosyl-L-methionine <=> bixin + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8238 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102821 +name: bixin methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: bixin + S-adenosyl-L-methionine <=> bixin dimethyl ester + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8239 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102822 +name: quercetin 3'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine = H+ + isorhamnetin + S-adenosyl-L-homocysteine." [EC:2.1.1.42, GOC:pz] +xref: EC:2.1.1.42 +xref: MetaCyc:RXN-8262 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102823 +name: kaempferol-3-rhamnoside-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8266 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102824 +name: UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8267 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102825 +name: quercetin 3-O-rhamnoside-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8268 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102826 +name: kaempferol-3-glucoside-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8270 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102827 +name: galactosylononitol-raffinose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol." [EC:2.4.1.67, GOC:pz] +xref: MetaCyc:RXN-8282 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102828 +name: stachyose galactinol:verbascose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8284 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102829 +name: ajugose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8285 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102830 +name: verbascose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8286 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102831 +name: stachyose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8287 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102832 +name: verbascose galactinol:ajugose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8288 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102833 +name: sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8292 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102834 +name: 1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8294 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102835 +name: 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8295 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102836 +name: 1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8296 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102837 +name: 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8297 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102838 +name: 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8298 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102839 +name: 1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8299 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102840 +name: 1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8301 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102841 +name: 1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8302 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102842 +name: 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8303 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102843 +name: 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8304 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102844 +name: 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8305 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102845 +name: 1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8307 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102846 +name: 1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8308 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102847 +name: 1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8309 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102848 +name: 1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8310 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102849 +name: 1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8314 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102850 +name: 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8316 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102851 +name: 1-18:2-2-16:0-phosphatidylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8318 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102852 +name: 1-18:3-2-16:0-phosphatidylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8319 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102853 +name: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8320 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102854 +name: 1-18:2-2-18:1-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8321 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102855 +name: 1-18:1-2-18:2-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8322 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102856 +name: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8323 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102857 +name: 1-18:1-2-18:3-phosphatidylcholinedesaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8324 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102858 +name: 1-18:2-2-18:3-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8325 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102859 +name: 1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8326 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102860 +name: 1-18:1-2-18:2-phosphatidylcholine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:1-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8327 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102861 +name: 1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8328 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102862 +name: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming) +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8329 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102863 +name: 1-18:3-2-18:1-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8330 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102864 +name: 1-18:3-2-18:2-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8331 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102865 +name: Delta6-acyl-lipid desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid gamma-linolenoyl group + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8343 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102866 +name: di-homo-gamma-linolenate Delta5 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8346 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102867 +name: molybdenum cofactor sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine <=> thio-molybdenum cofactor + L-alanine + H2O." [EC:2.8.1.9, GOC:pz] +xref: EC:2.8.1.9 +xref: MetaCyc:RXN-8351 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0102868 +name: 24-epi-campsterol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8352 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102869 +name: 6-hydroxyflavone-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8354 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102870 +name: 7-hydroxyflavone-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8355 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102871 +name: 1-16:0-2-18:1-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-16:0-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-palmitoyl-2-linoleoyl-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8360 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102872 +name: 1-16:0-2-18:2-phosphatidylcholine desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8361 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102873 +name: 1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8363 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102874 +name: 1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8365 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102875 +name: 1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-8366 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102876 +name: psoralen synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O." [EC:1.14.14.141, GOC:pz] +xref: EC:1.14.14.141 +xref: MetaCyc:RXN-8386 +xref: RHEA:19281 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102877 +name: alpha-copaene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid." [EC:4.2.3.133, GOC:pz] +xref: EC:4.2.3.133 +xref: MetaCyc:RXN-8416 +xref: RHEA:33991 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102878 +name: (+)-alpha-barbatene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid." [EC:4.2.3.69, GOC:pz] +xref: EC:4.2.3.69 +xref: MetaCyc:RXN-8417 +xref: RHEA:29499 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102879 +name: (+)-thujopsene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid." [EC:4.2.3.79, GOC:pz] +xref: EC:4.2.3.79 +xref: MetaCyc:RXN-8418 +xref: RHEA:30375 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102880 +name: isobazzanene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8419 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102881 +name: (+)-beta-barbatene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8421 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102882 +name: beta-acoradiene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8423 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102883 +name: (+)-beta-chamigrene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid." [EC:4.2.3.78, GOC:pz] +xref: EC:4.2.3.78 +xref: MetaCyc:RXN-8424 +xref: RHEA:30379 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102884 +name: alpha-zingiberene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid." [EC:4.2.3.65, GOC:pz] +xref: EC:4.2.3.65 +xref: MetaCyc:RXN-8425 +xref: RHEA:28643 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102885 +name: alpha-cuprenene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid." [EC:4.2.3.95, GOC:pz] +xref: EC:4.2.3.95 +xref: MetaCyc:RXN-8426 +xref: RHEA:32027 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102886 +name: alpha-chamigrene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8428 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102887 +name: beta-sesquiphellandrene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid." [EC:4.2.3.123, GOC:pz] +xref: EC:4.2.3.123 +xref: MetaCyc:RXN-8430 +xref: RHEA:32699 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102888 +name: delta-cuprenene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8431 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102889 +name: beta-elemene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8432 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102890 +name: naringenin chalcone 4'-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+." [EC:2.4.1.286, GOC:pz] +xref: EC:2.4.1.286 +xref: MetaCyc:RXN-8453 +xref: RHEA:34291 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102891 +name: 2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP." [EC:2.4.1.286, GOC:pz] +xref: EC:2.4.1.286 +xref: MetaCyc:RXN-8455 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102892 +name: betanidin 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8479 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102893 +name: betanidin 6-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8480 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102894 +name: UDPG:cyclo-DOPA 5-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8481 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102895 +name: colneleate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O." [EC:4.2.1.121, GOC:pz] +xref: EC:4.2.1.121 +xref: MetaCyc:RXN-8496 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102896 +name: colnelenate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O." [EC:4.2.1.121, GOC:pz] +xref: MetaCyc:RXN-8498 +is_a: GO:0016836 ! hydro-lyase activity + +[Term] +id: GO:0102897 +name: abietadienal hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8510 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102898 +name: levopimaradienol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8517 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102899 +name: dehydroabietadienol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8532 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102900 +name: dehydroabietadienal hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8534 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102901 +name: isopimaradienol hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8536 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102902 +name: isopimaradienal hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8538 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102903 +name: gamma-terpinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid." [GOC:pz, RHEA:32559] +xref: EC:4.2.3.114 +xref: MetaCyc:RXN-8547 +xref: RHEA:32559 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102904 +name: germacrene C synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid." [EC:4.2.3.60, GOC:pz] +xref: EC:4.2.3.60 +xref: MetaCyc:RXN-8561 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102905 +name: valencene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid." [EC:4.2.3.73, GOC:pz] +xref: EC:4.2.3.73 +xref: MetaCyc:RXN-8608 +xref: RHEA:29511 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102906 +name: 7-epi-alpha-selinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid." [EC:4.2.3.86, GOC:pz] +xref: EC:4.2.3.86 +xref: MetaCyc:RXN-8609 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102907 +name: sesquisabinene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8622 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102909 +name: alpha-ketoglutarate reductase activity (NADH-dependent) +namespace: molecular_function +def: "Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8645 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102910 +name: dirigent protein activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O." [EC:1.10.3.-, GOC:pz] +xref: MetaCyc:RXN-8677 +is_a: GO:0016682 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor + +[Term] +id: GO:0102911 +name: (-)-secoisolariciresinol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8680 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102912 +name: (-)-lactol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8681 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102913 +name: 3-aminomethylindole N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8686 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102914 +name: N-methyl-3-aminomethylindole N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-8687 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102915 +name: piperitol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8695 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102916 +name: sesamin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-8696 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102917 +name: (S)-reticuline 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine." [EC:2.1.1.291, GOC:pz] +xref: EC:2.1.1.291 +xref: MetaCyc:RXN-8700 +xref: RHEA:10444 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102918 +name: (R)-reticuline 7-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine + H+." [EC:2.1.1.291, GOC:pz] +xref: EC:2.1.1.291 +xref: MetaCyc:RXN-8701 +xref: RHEA:38907 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102919 +name: 5,6-dimethylbenzimidazole synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid." [EC:1.13.11.79, GOC:pz] +xref: EC:1.13.11.79 +xref: MetaCyc:RXN-8771 +xref: RHEA:27345 +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + +[Term] +id: GO:0102920 +name: acyl coenzyme A: isopenicillin N acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate." [EC:2.3.1.164, GOC:pz] +xref: EC:2.3.1.164 +xref: MetaCyc:RXN-8809 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102921 +name: mannosylglycerate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP." [EC:2.4.1.269, GOC:pz] +xref: EC:2.4.1.269 +xref: MetaCyc:RXN-8849 +xref: RHEA:30639 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102922 +name: phenylpropanoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8857 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102923 +name: 3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8859 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102924 +name: gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-886 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102925 +name: solanine UDP-galactose galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8875 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102926 +name: solanidine glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8882 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102927 +name: beta-chaconine rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8883 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102928 +name: beta-solanine rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-8884 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102929 +name: lachrymatory factor synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide." [EC:5.3.-.-, GOC:pz] +xref: MetaCyc:RXN-8911 +is_a: GO:0016860 ! intramolecular oxidoreductase activity + +[Term] +id: GO:0102930 +name: 4-hydroxybenzoate geranyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid." [GOC:pz, RHEA:27854] +xref: EC:2.5.1.93 +xref: MetaCyc:RXN-8920 +xref: RHEA:27854 +is_a: GO:0016765 ! transferase activity, transferring alkyl or aryl (other than methyl) groups + +[Term] +id: GO:0102931 +name: (Z,E)-alpha- farnesene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid." [EC:4.2.3.-, GOC:pz] +xref: MetaCyc:RXN-8931 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates + +[Term] +id: GO:0102932 +name: pterocarpan reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-8936 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102933 +name: GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate." [GOC:pz, RHEA:36779] +xref: EC:2.6.1.102 +xref: MetaCyc:RXN-8953 +xref: RHEA:36779 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0102934 +name: costunolide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP." [GOC:pz, RHEA:28230] +xref: EC:1.14.14.150 +xref: MetaCyc:RXN-8971 +xref: RHEA:28230 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102935 +name: gypsogenin-UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9012 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102936 +name: gypsogenate-UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9013 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102937 +name: 16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9014 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102938 +name: orcinol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: orcinol + S-adenosyl-L-methionine = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine." [EC:2.1.1.6, GOC:pz] +xref: EC:2.1.1.6 +xref: MetaCyc:RXN-9017 +is_a: GO:0008168 ! methyltransferase activity +property_value: RO:0002161 NCBITaxon:4890 + +[Term] +id: GO:0102939 +name: 3-methoxy-5-hydroxytoluene O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9018 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102940 +name: phloroglucinol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9020 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102941 +name: 3,5-dihydroxyanisole O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9021 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102942 +name: 3,5-dimethoxyphenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9022 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102943 +name: trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate." [GOC:pz, RHEA:28182] +xref: EC:5.3.3.17 +xref: MetaCyc:RXN-9031 +xref: RHEA:28182 +is_a: GO:0016863 ! intramolecular oxidoreductase activity, transposing C=C bonds + +[Term] +id: GO:0102944 +name: medicagenate UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9035 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102945 +name: soyasapogenol B UDP-glucosyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9037 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102946 +name: soyasapogenol E UDP-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9038 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102947 +name: (+)-delta-cadinene-8-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9045 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102948 +name: luteolin C-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9081 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102949 +name: 1,2-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9082 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102950 +name: indole-3-acetyl-valine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-9083 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102951 +name: indole-3-acetyl-phenylalanine synthetase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid." [EC:6.3.-.-, GOC:pz] +xref: MetaCyc:RXN-9084 +is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds + +[Term] +id: GO:0102952 +name: UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-91 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102953 +name: hypoglycin A gamma-glutamyl transpeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B." [EC:2.3.2.2, GOC:pz] +xref: EC:2.3.2.2 +xref: MetaCyc:RXN-9157 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0102954 +name: dalcochinase activity +namespace: molecular_function +def: "Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose." [EC:3.2.1.-, GOC:pz] +xref: MetaCyc:RXN-9162 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0102955 +name: S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+." [GOC:pz, PMID:1444716, PMID:9045837, RHEA:33255] +xref: EC:2.1.1.163 +xref: MetaCyc:RXN-9191 +xref: RHEA:33255 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102956 +name: UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-92 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102960 +name: momilactone-A synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H." [GOC:pz, RHEA:25367] +xref: EC:1.1.1.295 +xref: MetaCyc:RXN-9290 +xref: RHEA:25367 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102961 +name: 4,4'-diapophytofluene desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2." [EC:1.3.8.-, GOC:pz] +xref: MetaCyc:RXN-9304 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102962 +name: 4,4'-diapo-zeta-carotene desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2." [EC:1.3.8.-, GOC:pz] +xref: MetaCyc:RXN-9305 +is_a: GO:0052890 ! oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor + +[Term] +id: GO:0102963 +name: (S)-corytuberine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O." [EC:1.14.21.-, GOC:pz] +xref: MetaCyc:RXN-9314 +is_a: GO:0046996 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated + +[Term] +id: GO:0102964 +name: S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine <=> H+ + magnoflorine + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9315 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102965 +name: alcohol-forming fatty acyl-CoA reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol." [EC:1.2.1.84, GOC:pz] +xref: EC:1.2.1.84 +xref: MetaCyc:RXN-9344 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102966 +name: arachidoyl-CoA:1-dodecanol O-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A." [EC:2.3.1.75, GOC:pz] +xref: EC:2.3.1.75 +xref: MetaCyc:RXN-9356 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102967 +name: 10-hydroxygeraniol oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9367 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102968 +name: 10-hydroxygeranial oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9369 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102969 +name: 10-oxogeraniol oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9370 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102970 +name: 7-deoxyloganetic acid glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP." [EC:2.4.1.323, GOC:pz] +xref: EC:2.4.1.323 +xref: MetaCyc:RXN-9372 +xref: RHEA:39895 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102971 +name: phosphinothricin N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate." [EC:2.3.1.183, GOC:pz] +xref: EC:2.3.1.183 +xref: MetaCyc:RXN-9382 +xref: RHEA:12597 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102972 +name: gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming) +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-947 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0102973 +name: norsolorinate anthrone synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein]." [EC:2.3.1.221, GOC:pz] +synonym: "norsolorinic acid synthase" EXACT [] +xref: EC:2.3.1.221 +xref: MetaCyc:RXN-9479 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102974 +name: hydroxyversicolorone reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH." [GOC:pz, RHEA:35691] +xref: EC:1.1.1.353 +xref: MetaCyc:RXN-9489 +xref: RHEA:35691 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102975 +name: versiconal hemiacetal acetate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH." [EC:1.1.1.353, GOC:pz] +xref: EC:1.1.1.353 +xref: MetaCyc:RXN-9490 +xref: RHEA:35695 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102976 +name: versiconal reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+." [EC:1.1.1.353, GOC:pz] +xref: EC:1.1.1.353 +xref: MetaCyc:RXN-9491 +xref: RHEA:35699 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102977 +name: nitrilotriacetate monooxygenase activity (FMN-dependent) +namespace: molecular_function +def: "Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN." [EC:1.14.14.10, GOC:pz] +xref: EC:1.14.14.10 +xref: MetaCyc:RXN-9508 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102978 +name: furaneol oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+." [EC:1.3.1.105, GOC:pz] +xref: EC:1.3.1.105 +xref: MetaCyc:RXN-9563 +xref: RHEA:39111 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102979 +name: homofuraneol oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-9564 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102980 +name: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-9565 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102981 +name: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-9567 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102982 +name: UDP-3-dehydro-alpha-D-glucose dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9578 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102983 +name: xylogalacturonan beta-1,3-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan." [EC:2.4.2.41, GOC:pz] +xref: EC:2.4.2.41 +xref: MetaCyc:RXN-9589 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0102984 +name: sulfoacetaldehyde dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+." [EC:1.2.1.73, GOC:pz] +xref: EC:1.2.1.73 +xref: MetaCyc:RXN-9592 +xref: RHEA:25637 +is_a: GO:0016620 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102985 +name: Delta12-fatty-acid desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.6, GOC:pz] +xref: EC:1.14.19.6 +xref: MetaCyc:RXN-9601 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102986 +name: trehalose synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate." [EC:2.4.1.245, GOC:pz] +xref: EC:2.4.1.245 +xref: MetaCyc:RXN-9603 +xref: RHEA:47416 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102987 +name: palmitoleic acid delta 12 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-9616 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102988 +name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-9617 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102989 +name: 5-pentadecatrienylresorcinol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide." [EC:2.3.1.-, GOC:pz] +xref: MetaCyc:RXN-9618 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0102990 +name: 5-n-alk(en)ylresorcinol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9619 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0102991 +name: myristoyl-CoA hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A." [EC:3.1.2.2, GOC:pz] +xref: EC:3.1.2.2 +xref: MetaCyc:RXN-9626 +is_a: GO:0016790 ! thiolester hydrolase activity + +[Term] +id: GO:0102992 +name: 2-methylbutyronitrile hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9642 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102993 +name: linolenate Delta15 desaturase activity +namespace: molecular_function +def: "Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor." [EC:1.14.19.-, GOC:pz] +xref: MetaCyc:RXN-9667 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + +[Term] +id: GO:0102995 +name: angelicin synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O." [EC:1.14.14.148, GOC:pz] +xref: EC:1.14.14.148 +xref: MetaCyc:RXN-9689 +xref: RHEA:27481 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0102996 +name: beta,beta digalactosyldiacylglycerol galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol." [EC:2.4.1.184, GOC:pz] +xref: EC:2.4.1.184 +xref: MetaCyc:RXN-9721 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0102997 +name: progesterone 5beta- reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP." [EC:1.3.1.-, GOC:pz] +xref: MetaCyc:RXN-9726 +is_a: GO:0016628 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0102998 +name: 4-sulfomuconolactone hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+." [EC:3.1.1.92, GOC:pz] +xref: EC:3.1.1.92 +xref: MetaCyc:RXN-9733 +xref: RHEA:33711 +is_a: GO:0052689 ! carboxylic ester hydrolase activity + +[Term] +id: GO:0102999 +name: UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9743 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103000 +name: UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN-9748 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103001 +name: dimethylsulfoxide oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9767 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103002 +name: 16-hydroxypalmitate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN-9802 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103003 +name: oleate peroxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol." [EC:1.11.-.-, GOC:pz] +xref: MetaCyc:RXN-9804 +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor + +[Term] +id: GO:0103004 +name: 9,10-epoxystearate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9805 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103005 +name: 9,10-epoxystearate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate." [EC:3.3.2.-, GOC:pz] +xref: MetaCyc:RXN-9806 +is_a: GO:0016803 ! ether hydrolase activity + +[Term] +id: GO:0103006 +name: 9,10-dihydroxystearate hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9807 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103007 +name: indole-3-acetate carboxyl methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine." [EC:2.1.1.278, GOC:pz] +xref: EC:2.1.1.278 +xref: MetaCyc:RXN-9825 +xref: RHEA:36131 +is_a: GO:0008168 ! methyltransferase activity + +[Term] +id: GO:0103008 +name: 4-chloro-2-methylphenoxyacetate oxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-9864 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103009 +name: 3-chlorotoluene monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN-9908 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103010 +name: gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming) +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN-991 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103011 +name: mannosylfructose-phosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP." [EC:2.4.1.246, GOC:pz] +xref: EC:2.4.1.246 +xref: MetaCyc:RXN-9935 +xref: RHEA:26039 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103012 +name: ferredoxin-thioredoxin reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin." [GOC:pz, RHEA:42336] +xref: EC:1.8.7.2 +xref: MetaCyc:RXN-9944 +xref: RHEA:42336 +is_a: GO:0016673 ! oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor + +[Term] +id: GO:0103014 +name: beta-keto ester reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-1941 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103015 +name: 4-amino-4-deoxy-L-arabinose transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate." [EC:2.4.2.43, GOC:pz] +xref: EC:2.4.2.43 +xref: MetaCyc:RXN0-2001 +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups + +[Term] +id: GO:0103016 +name: tRNA-specific 2-thiouridylase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine." [GOC:pz, PMID:12949933] +xref: MetaCyc:RXN0-2023 +is_a: GO:0016874 ! ligase activity + +[Term] +id: GO:0103020 +name: 1-deoxy-D-xylulose kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP." [GOC:pz, PMID:11168365, PMID:16920870] +xref: MetaCyc:RXN0-382 +xref: RHEA:27990 +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0103023 +name: ITPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ITP + H2O <=> H+ + IDP + hydrogenphosphate." [EC:3.6.1.-, GOC:pz] +xref: MetaCyc:RXN0-5073 +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + +[Term] +id: GO:0103025 +name: alpha-amylase activity (releasing maltohexaose) +namespace: molecular_function +def: "Catalysis of the reaction: n H2O + a 1,4-alpha-D-glucan = alpha-maltohexaose + a 1,4-alpha-D-glucan." [EC:3.2.1.1, GOC:pz] +xref: EC:3.2.1.1 +xref: MetaCyc:RXN0-5181 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0103026 +name: fructose-1-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN0-5186 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0103027 +name: FMN phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate." [EC:3.1.3.-, GOC:pz] +xref: MetaCyc:RXN0-5187 +is_a: GO:0016791 ! phosphatase activity + +[Term] +id: GO:0103028 +name: murein hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide." [EC:4.2.2.-, GOC:pz] +xref: MetaCyc:RXN0-5190 +is_a: GO:0016837 ! carbon-oxygen lyase activity, acting on polysaccharides + +[Term] +id: GO:0103030 +name: ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-5213 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103031 +name: L-Ala-D/L-Glu epimerase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate." [EC:5.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-5228 +is_a: GO:0016855 ! racemase and epimerase activity, acting on amino acids and derivatives + +[Term] +id: GO:0103032 +name: tartronate semialdehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-5289 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103033 +name: beta-galactosidase activity (lactose isomerization) +namespace: molecular_function +def: "Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose." [EC:5.4.1.-, GOC:pz] +xref: MetaCyc:RXN0-5363 +is_a: GO:0016867 ! intramolecular transferase activity, transferring acyl groups + +[Term] +id: GO:0103035 +name: NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP." [EC:1.6.5.-, GOC:pz] +xref: MetaCyc:RXN0-5387 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0103036 +name: NADH:menaquinone oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol." [GOC:pz] +xref: MetaCyc:RXN0-5388 +is_a: GO:0016655 ! oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor + +[Term] +id: GO:0103037 +name: L-glyceraldehyde 3-phosphate reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-5410 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103039 +name: protein methylthiotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor." [EC:2.8.4.4, GOC:pz] +xref: EC:2.8.4.4 +xref: MetaCyc:RXN0-6366 +is_a: GO:0035596 ! methylthiotransferase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein + +[Term] +id: GO:0103040 +name: aldose sugar dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor." [EC:1.1.5.-, GOC:pz] +xref: MetaCyc:RXN0-6371 +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor + +[Term] +id: GO:0103041 +name: thiosulfate-thioredoxin sulfurtransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin." [EC:2.8.1.-, GOC:pz] +xref: MetaCyc:RXN0-6385 +is_a: GO:0016783 ! sulfurtransferase activity + +[Term] +id: GO:0103042 +name: 4-hydroxy-L-threonine aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine." [EC:4.1.2.-, GOC:pz] +xref: MetaCyc:RXN0-6563 +is_a: GO:0016832 ! aldehyde-lyase activity + +[Term] +id: GO:0103043 +name: 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate." [EC:3.1.4.55, GOC:pz] +xref: EC:3.1.4.55 +xref: MetaCyc:RXN0-6710 +xref: RHEA:34795 +is_a: GO:0008081 ! phosphoric diester hydrolase activity + +[Term] +id: GO:0103044 +name: ribosomal protein S6 glutamate-glutamate ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate." [EC:6.3.2.-, GOC:pz] +xref: MetaCyc:RXN0-6726 +is_a: GO:0018169 ! ribosomal S6-glutamic acid ligase activity + +[Term] +id: GO:0103045 +name: methione N-acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+." [EC:2.3.1.1, GOC:pz] +xref: EC:2.3.1.1 +xref: MetaCyc:RXN0-6948 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0103046 +name: alanylglutamate dipeptidase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate." [EC:3.4.13.18, GOC:pz] +xref: EC:3.4.13.18 +xref: MetaCyc:RXN0-6981 +is_a: GO:0016805 ! dipeptidase activity + +[Term] +id: GO:0103047 +name: methyl beta-D-glucoside 6-phosphate glucohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol." [EC:3.2.1.86, GOC:pz] +xref: EC:3.2.1.86 +xref: MetaCyc:RXN0-6994 +is_a: GO:0004553 ! hydrolase activity, hydrolyzing O-glycosyl compounds + +[Term] +id: GO:0103048 +name: tRNA m2A37 methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA." [EC:2.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-7007 +is_a: GO:0016426 ! tRNA (adenine) methyltransferase activity + +[Term] +id: GO:0103050 +name: isobutyraldehyde reductase activity +namespace: molecular_function +def: "Catalysis of the reaction: isobutanol + NADP <=> isobutyraldehyde + NADPH + H+." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXN0-7119 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103051 +name: N1-methyladenine demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-methyladenine + O2 + 2-oxoglutarate <=> adenine + carbon dioxide + formaldehyde + succinate." [EC:1.14.11.33, GOC:pz] +xref: MetaCyc:RXN0-984 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103052 +name: N3-methylcytosine demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: N3-methylcytosine + O2 + 2-oxoglutarate <=> H+ + cytosine + carbon dioxide + formaldehyde + succinate." [EC:1.14.11.33, GOC:pz] +xref: MetaCyc:RXN0-985 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103053 +name: 1-ethyladenine demethylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-ethyladenine + O2 + 2-oxoglutarate(2-) <=> adenine + carbon dioxide + acetaldehyde + succinate." [EC:1.14.11.33, GOC:pz] +xref: EC:1.14.11.33 +xref: MetaCyc:RXN0-986 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103054 +name: gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming) +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN1F-162 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103055 +name: gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN1F-163 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103056 +name: gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN1F-167 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103057 +name: gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate." [EC:1.14.11.-, GOC:pz] +xref: MetaCyc:RXN1F-169 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity + +[Term] +id: GO:0103058 +name: kaempferol 3-glucoside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN1F-443 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103059 +name: UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-)." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN1F-474 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103060 +name: kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN1F-475 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103061 +name: trans-methoxy-C60-meroacyl-AMP ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein]." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN1G-4141 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0103062 +name: cis-keto-C60-meroacyl-AMP ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN1G-4142 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0103063 +name: trans-keto-C61-meroacyl-AMP ligase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]." [EC:6.2.1.-, GOC:pz] +xref: MetaCyc:RXN1G-4143 +is_a: GO:0016878 ! acid-thiol ligase activity + +[Term] +id: GO:0103064 +name: inositol phosphorylceramide mannosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: GDP-alpha-D-mannose + an inositol-phospho-alpha hydroxyphytoceramide = H+ + GDP + a mannosyl-inositol-phospho-alpha hydroxyphytoceramide." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXN3O-663 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103066 +name: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H." [EC:1.1.1.170, GOC:pz] +xref: EC:1.1.1.170 +xref: MetaCyc:RXN66-18 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103067 +name: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity +namespace: molecular_function +def: "Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H." [EC:1.1.1.170, GOC:pz] +xref: EC:1.1.1.170 +xref: MetaCyc:RXN66-23 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103068 +name: leukotriene C4 gamma-glutamyl transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid." [GOC:pz, PMID:1676842, PMID:9139674] +xref: EC:2.3.2.2 +xref: MetaCyc:RXN66-336 +is_a: GO:0016755 ! transferase activity, transferring amino-acyl groups + +[Term] +id: GO:0103069 +name: 17-hydroxyprogesterone 21-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: 17alpha-hydroxyprogesterone + NADPH + H+ + O2 <=> NADP + H2O + 11-deoxycortisol." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXN66-356 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103071 +name: 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA <=> formyl-CoA + a 2-methyl branched 2,3,4-saturated fatty aldehyde." [EC:4.1.-.-, GOC:pz] +xref: MetaCyc:RXN66-471 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0103072 +name: straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity +namespace: molecular_function +def: "Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde." [EC:4.1.-.-, GOC:pz] +xref: MetaCyc:RXN66-475 +is_a: GO:0016830 ! carbon-carbon lyase activity + +[Term] +id: GO:0103073 +name: anandamide amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+)." [EC:3.5.1.99, GOC:pz] +xref: EC:3.5.1.99 +xref: MetaCyc:RXN6666-2 +xref: RHEA:26136 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0103074 +name: glucose-6-phosphate 3-dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate." [GOC:pz, RHEA:37547] +xref: EC:1.1.1.361 +xref: MetaCyc:RXN8J2-136 +xref: RHEA:37547 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103075 +name: indole-3-pyruvate monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O." [EC:1.14.13.168, GOC:pz] +xref: EC:1.14.13.168 +xref: MetaCyc:RXNDQC-2 +xref: RHEA:34331 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103077 +name: quercetin 3-glucoside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4161 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103078 +name: quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4162 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103079 +name: 2-(3'-methylthio)propylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A." [EC:2.3.3.-, GOC:pz] +xref: MetaCyc:RXNQT-4163 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0103080 +name: methylthiopropylmalate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate." [EC:5.4.4.-, GOC:pz] +xref: MetaCyc:RXNQT-4164 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0103081 +name: methylthiopropylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(3'-methylthio)propylmalate <=> H+ + 2-oxo-6-methylthiohexanoate + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4165 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103082 +name: 2-(4'-methylthio)butylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A." [EC:2.3.3.-, GOC:pz] +xref: MetaCyc:RXNQT-4166 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0103083 +name: methylthiobutylmalate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate." [EC:5.4.4.-, GOC:pz] +xref: MetaCyc:RXNQT-4167 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0103084 +name: methylthiobutylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(4'-methylthio)butylmalate <=> H+ + 2-oxo-7-methylthioheptanoate + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4168 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103085 +name: 2-(5'-methylthio)pentylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A." [EC:2.3.3.-, GOC:pz] +xref: MetaCyc:RXNQT-4169 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0103086 +name: methylthiopentylmalate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate." [EC:5.4.4.-, GOC:pz] +xref: MetaCyc:RXNQT-4170 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0103087 +name: methylthiopentylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(5'-methylthio)pentylmalate <=> H+ + 2-oxo-8-methylthiooctanoate + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4171 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103088 +name: 2-(6'-methylthio)hexylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A." [EC:2.3.3.-, GOC:pz] +xref: MetaCyc:RXNQT-4172 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0103089 +name: methylthiohexylmalate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate." [EC:5.4.4.-, GOC:pz] +xref: MetaCyc:RXNQT-4173 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0103090 +name: methylthiohexylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(6'-methylthio)hexylmalate <=> H+ + 2-oxo-9-methylthiononanoate + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4174 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103091 +name: 2-(7'-methylthio)heptylmalate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A." [EC:2.3.3.-, GOC:pz] +xref: MetaCyc:RXNQT-4175 +is_a: GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + +[Term] +id: GO:0103092 +name: methylthioalkylmalate isomerase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate." [EC:5.4.4.-, GOC:pz] +xref: MetaCyc:RXNQT-4176 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups + +[Term] +id: GO:0103093 +name: methylthioalkylmalate dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide." [EC:1.1.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4178 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + +[Term] +id: GO:0103096 +name: CYP79F1 dihomomethionine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXNQT-4309 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103097 +name: CYP79F1 trihomomethionine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXNQT-4310 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103098 +name: CYP79F1 tetrahomomethionine monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime." [EC:1.14.13.-, GOC:pz] +xref: MetaCyc:RXNQT-4311 +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + +[Term] +id: GO:0103099 +name: UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXNQT-4324 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103100 +name: UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-)." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXNQT-4325 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103101 +name: UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXNQT-4326 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103102 +name: UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXNQT-4327 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103103 +name: UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+." [EC:2.4.1.195, GOC:pz] +xref: EC:2.4.1.195 +xref: MetaCyc:RXNQT-4328 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103104 +name: 6-methylthiohexyldesulfoglucosinolate sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate." [EC:2.8.2.-, GOC:pz] +xref: MetaCyc:RXNQT-4331 +is_a: GO:0008146 ! sulfotransferase activity + +[Term] +id: GO:0103105 +name: 2-oxo-6-methylthiohexanoate aminotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate." [EC:2.6.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4345 +is_a: GO:0008483 ! transaminase activity + +[Term] +id: GO:0103106 +name: brassinolide 23-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4397 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103107 +name: castasterone 23-O-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+." [EC:2.4.1.-, GOC:pz] +xref: MetaCyc:RXNQT-4398 +is_a: GO:0016758 ! transferase activity, transferring hexosyl groups + +[Term] +id: GO:0103111 +name: D-glucosamine PTS permease activity +namespace: molecular_function +def: "Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine." [EC:2.7.1.69, GOC:pz] +xref: EC:2.7.1.69 +xref: MetaCyc:TRANS-RXN-167A +is_a: GO:0016773 ! phosphotransferase activity, alcohol group as acceptor + +[Term] +id: GO:0103113 +name: glucosyl-oleandomycin-exporting ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucosyl-oleandomycin + ATP + H2O <=> glucosyl-oleandomycin + ADP + hydrogenphosphate + H+." [EC:3.6.3.-, GOC:pz] +xref: MetaCyc:TRANS-RXN-220 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0103116 +name: ATPase-coupled alpha-D-galactofuranose transporter activity +namespace: molecular_function +def: "Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+." [GOC:pz] +synonym: "alpha-D-galactofuranose transporter activity" EXACT [] +synonym: "ATP-dependent alpha-D-galactofuranose transporter activity" EXACT [] +xref: MetaCyc:TRANS-RXN0-491 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity + +[Term] +id: GO:0103117 +name: UDP-3-O-acyl-N-acetylglucosamine deacetylase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate." [EC:3.5.1.108, GOC:pz] +xref: EC:3.5.1.108 +xref: MetaCyc:UDPACYLGLCNACDEACETYL-RXN +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + +[Term] +id: GO:0103118 +name: UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity +namespace: molecular_function +alt_id: GO:0043764 +def: "Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein]." [EC:2.3.1.191, GOC:pz] +synonym: "UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity" RELATED [] +xref: EC:2.3.1.191 +xref: MetaCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-RXN +xref: RHEA:17817 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups + +[Term] +id: GO:0104004 +name: cellular response to environmental stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus." [GOC:dos] +is_a: GO:0051716 ! cellular response to stimulus +created_by: dos +creation_date: 2017-02-17T16:02:42Z + +[Term] +id: GO:0104005 +name: obsolete hijacked molecular function +namespace: molecular_function +def: "OBSOLETE. A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor." [GOC:pdt] +comment: This term was obsoleted because it was an unnecessary grouping class. +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16741 xsd:anyURI +is_obsolete: true +created_by: dos +creation_date: 2017-08-04T02:12:09Z + +[Term] +id: GO:0106001 +name: intestinal hexose absorption +namespace: biological_process +def: "Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine." [GOC:hjd] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0050892 ! intestinal absorption + +[Term] +id: GO:0106002 +name: mCRD-mediated mRNA stability complex +namespace: cellular_component +def: "A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP." [GOC:bhm, PMID:11051545] +comment: This complex is related to GO:0070937 CRD-mediated mRNA stability complex but binds the major protein-coding-region determinant of instability (mCRD) domain rather than the CRD. Experimentally it has been shown to act on c-FOS mRNA while GO:0070937 acts on c-MYC mRNA. +synonym: "major coding region determinant of instability-mediated mRNA stability complex" EXACT [] +synonym: "major coding region instability determinant-mediated mRNA stability complex" EXACT [] +synonym: "major coding region instability determinant-poly(A)-bridging complex" EXACT [] +synonym: "major coding-region determinant of instability - poly(A) tail-bridging complex" EXACT [] +synonym: "mCRD-poly(A)-bridging complex" EXACT [] +xref: IntAct:EBI-13948957 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol + +[Term] +id: GO:0106003 +name: amyloid-beta complex +namespace: cellular_component +def: "Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease." [GOC:bhm, PMID:18568035] +comment: An example is Protein 40 of APP (P05067-PRO_0000000093) in PMID:18568035 (inferred by direct assay). +synonym: "Abeta complex" EXACT [] +synonym: "Abeta-derived diffusible ligand complex" NARROW [] +synonym: "ADDL complex" NARROW [] +synonym: "amyloid beta complex" EXACT [] +synonym: "amyloid beta dimer" NARROW [] +synonym: "amyloid beta heterodimer" NARROW [] +synonym: "amyloid beta heterooligomer" NARROW [] +synonym: "amyloid beta heterotrimer" NARROW [] +synonym: "amyloid beta homodimer" NARROW [] +synonym: "amyloid beta homooligomer" NARROW [] +synonym: "amyloid beta homotrimer" NARROW [] +synonym: "amyloid beta oligomer" NARROW [] +synonym: "amyloid beta trimer" NARROW [] +synonym: "amyloid-beta protein 40 complex" NARROW [] +synonym: "amyloid-beta protein 40/42 complex" NARROW [] +synonym: "amyloid-beta protein 42 complex" NARROW [] +synonym: "beta amyloid complex" EXACT [] +synonym: "beta-amyloid complex" EXACT [] +synonym: "betaA complex" EXACT [] +synonym: "heterodimer of amyloid beta protein" NARROW [] +synonym: "heterooligomer of amyloid beta protein" NARROW [] +synonym: "heterotrimer of amyloid beta protein" NARROW [] +synonym: "homodimer of amyloid beta protein" NARROW [] +synonym: "homooligomer of amyloid beta protein" NARROW [] +synonym: "homotrimer of amyloid beta protein" NARROW [] +is_a: GO:0032991 ! protein-containing complex +created_by: hjd +creation_date: 2017-03-15T19:19:29Z + +[Term] +id: GO:0106004 +name: tRNA (guanine-N7)-methylation +namespace: biological_process +def: "The process whereby a guanine in a tRNA is methylated at the N7 position of guanine." [GOC:hjd, PMID:17382321] +is_a: GO:0030488 ! tRNA methylation +is_a: GO:0036265 ! RNA (guanine-N7)-methylation +created_by: hjd +creation_date: 2017-04-07T18:17:38Z + +[Term] +id: GO:0106005 +name: RNA 5'-cap (guanine-N7)-methylation +namespace: biological_process +def: "The process whereby a guanine in 5-cap is methylated at the N7 position of guanine." [GOC:hjd] +is_a: GO:0036265 ! RNA (guanine-N7)-methylation +relationship: part_of GO:0009452 ! 7-methylguanosine RNA capping +created_by: hjd +creation_date: 2017-04-07T19:19:57Z + +[Term] +id: GO:0106006 +name: cytoskeletal protein-membrane anchor activity +namespace: molecular_function +alt_id: GO:0140362 +def: "The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location." [PMID:25736293, PMID:30840879] +synonym: "BAR domain adaptor" NARROW [] +synonym: "cytoskeletal protein membrane adaptor" EXACT [] +synonym: "cytoskeletal protein membrane adaptor activity" EXACT [] +synonym: "cytoskeletal protein membrane anchor activity" EXACT [] +synonym: "cytoskeletal protein-membrane adaptor activity" EXACT [] +synonym: "F-BAR domain adaptor" NARROW [] +synonym: "membrane-cytoskeletal protein anchor activity" EXACT [] +synonym: "microtubule cortical anchor activity" NARROW [] +is_a: GO:0008093 ! cytoskeletal anchor activity +is_a: GO:0043495 ! protein-membrane adaptor activity +relationship: has_part GO:0008289 ! lipid binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17668 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18281 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19119 xsd:anyURI +created_by: hjd +creation_date: 2017-04-14T15:11:13Z + +[Term] +id: GO:0106007 +name: microtubule anchoring at cell cortex of cell tip +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex." [GOC:mah, PMID:25736293] +is_a: GO:0034453 ! microtubule anchoring +created_by: hjd +creation_date: 2017-04-19T15:12:45Z + +[Term] +id: GO:0106008 +name: 2-oxoglutaramate amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3)." [EC:3.5.1.111, PMID:21288482] +xref: EC:3.5.1.111 +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: hjd +creation_date: 2017-04-25T14:10:02Z + +[Term] +id: GO:0106009 +name: (4S)-4-hydroxy-2-oxoglutarate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate." [EC:4.1.3.42, GOC:hjd, PMID:1098660, PMID:1339418] +xref: EC:4.1.3.42 +is_a: GO:0016833 ! oxo-acid-lyase activity +created_by: hjd +creation_date: 2017-04-25T14:14:58Z + +[Term] +id: GO:0106011 +name: regulation of protein localization to medial cortex +namespace: biological_process +def: "Any process that regulates the localization of a protein to the medial cortex." [GOC:hjd] +is_a: GO:1901900 ! regulation of protein localization to cell division site +is_a: GO:1904776 ! regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071574 ! protein localization to medial cortex +relationship: regulates GO:0071574 ! protein localization to medial cortex +created_by: hjd +creation_date: 2017-04-27T17:29:56Z + +[Term] +id: GO:0106012 +name: positive regulation of protein localization to medial cortex +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex." [GOC:hjd, PMID:19474789] +is_a: GO:0106011 ! regulation of protein localization to medial cortex +is_a: GO:1904778 ! positive regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071574 ! protein localization to medial cortex +relationship: positively_regulates GO:0071574 ! protein localization to medial cortex +created_by: hjd +creation_date: 2017-04-27T17:36:17Z + +[Term] +id: GO:0106013 +name: negative regulation of protein localization to cell cortex of cell tip +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip." [GOC:vw, PMID:19474792] +is_a: GO:1990895 ! regulation of protein localization to cell cortex of cell tip +created_by: hjd +creation_date: 2017-04-28T13:45:38Z + +[Term] +id: GO:0106014 +name: regulation of inflammatory response to wounding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the inflammatory response to wounding." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26022821] +is_a: GO:0050727 ! regulation of inflammatory response +is_a: GO:1903034 ! regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090594 ! inflammatory response to wounding +relationship: regulates GO:0090594 ! inflammatory response to wounding +created_by: hjd +creation_date: 2017-04-28T20:03:14Z + +[Term] +id: GO:0106015 +name: negative regulation of inflammatory response to wounding +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26022821] +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0106014 ! regulation of inflammatory response to wounding +is_a: GO:1903035 ! negative regulation of response to wounding +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0090594 ! inflammatory response to wounding +relationship: negatively_regulates GO:0090594 ! inflammatory response to wounding +created_by: hjd +creation_date: 2017-04-28T20:09:46Z + +[Term] +id: GO:0106016 +name: positive regulation of inflammatory response to wounding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26022821] +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0106014 ! regulation of inflammatory response to wounding +is_a: GO:1903036 ! positive regulation of response to wounding +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0090594 ! inflammatory response to wounding +relationship: positively_regulates GO:0090594 ! inflammatory response to wounding +created_by: hjd +creation_date: 2017-04-28T20:16:31Z + +[Term] +id: GO:0106017 +name: phosphatidylinositol-3,4-bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate." [GOC:hjd] +is_a: GO:0034593 ! phosphatidylinositol bisphosphate phosphatase activity +created_by: hjd +creation_date: 2017-05-10T14:08:06Z + +[Term] +id: GO:0106018 +name: phosphatidylinositol-3,5-bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate." [GOC:hjd] +is_a: GO:0034593 ! phosphatidylinositol bisphosphate phosphatase activity +created_by: hjd +creation_date: 2017-05-10T14:19:13Z + +[Term] +id: GO:0106019 +name: phosphatidylinositol-4,5-bisphosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate." [GOC:hjd] +is_a: GO:0034593 ! phosphatidylinositol bisphosphate phosphatase activity +created_by: hjd +creation_date: 2017-05-10T14:22:12Z + +[Term] +id: GO:0106020 +name: regulation of vesicle docking +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vesicle docking." [PMID:22810233] +synonym: "regulation of vesicle to membrane docking" EXACT [] +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048278 ! vesicle docking +relationship: regulates GO:0048278 ! vesicle docking +created_by: hjd +creation_date: 2017-05-16T13:58:54Z + +[Term] +id: GO:0106021 +name: negative regulation of vesicle docking +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking." [PMID:22810233] +synonym: "negative regulation of vesicle to membrane docking" EXACT [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0106020 ! regulation of vesicle docking +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048278 ! vesicle docking +relationship: negatively_regulates GO:0048278 ! vesicle docking +created_by: hjd +creation_date: 2017-05-16T14:05:29Z + +[Term] +id: GO:0106022 +name: positive regulation of vesicle docking +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vesicle docking." [PMID:22810233] +synonym: "positive regulation of vesicle to membrane docking" EXACT [] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0106020 ! regulation of vesicle docking +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048278 ! vesicle docking +relationship: positively_regulates GO:0048278 ! vesicle docking +created_by: hjd +creation_date: 2017-05-16T14:12:32Z + +[Term] +id: GO:0106023 +name: regulation of pupariation +namespace: biological_process +def: "Any process that modulates the onset of pupariation." [PMID:26510564] +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035073 ! pupariation +relationship: regulates GO:0035073 ! pupariation +created_by: hjd +creation_date: 2017-05-24T19:31:39Z + +[Term] +id: GO:0106024 +name: negative regulation of pupariation +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of onset of pupariation." [PMID:26510564] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0106023 ! regulation of pupariation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035073 ! pupariation +relationship: negatively_regulates GO:0035073 ! pupariation +created_by: hjd +creation_date: 2017-05-24T19:35:29Z + +[Term] +id: GO:0106025 +name: positive regulation of pupariation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of onset of pupariation." [GOC:hjd] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0106023 ! regulation of pupariation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035073 ! pupariation +relationship: positively_regulates GO:0035073 ! pupariation +created_by: hjd +creation_date: 2017-05-24T19:37:50Z + +[Term] +id: GO:0106026 +name: Gly-tRNA(Ala) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala)." [PMID:28362257] +is_a: GO:0002161 ! aminoacyl-tRNA editing activity +created_by: hjd +creation_date: 2017-06-16T17:13:33Z + +[Term] +id: GO:0106027 +name: neuron projection organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +created_by: hjd +creation_date: 2017-06-23T18:30:18Z + +[Term] +id: GO:0106028 +name: neuron projection retraction +namespace: biological_process +def: "The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:aruk, GOC:bc, PMID:11585923.] +synonym: "neuron projection disassembly" EXACT [] +is_a: GO:0106027 ! neuron projection organization +created_by: hjd +creation_date: 2017-06-23T18:32:42Z + +[Term] +id: GO:0106029 +name: tRNA pseudouridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [PMID:11095668] +synonym: "Mitochondrial tRNA pseudouridine(27/28) synthase" NARROW [EC:5.4.99.44] +synonym: "transfer ribonucleate pseudouridine synthetase activity" EXACT [] +synonym: "transfer RNA pseudouridine synthetase activity" EXACT [] +synonym: "tRNA pseudouridine(13) synthase" NARROW [EC:5.4.99.27] +synonym: "tRNA pseudouridine(31) synthase" NARROW [EC:5.4.99.42] +synonym: "tRNA pseudouridine(32) synthase" NARROW [EC:5.4.99.28] +synonym: "tRNA pseudouridine(38-40) synthase" NARROW [EC:5.4.99.12] +synonym: "tRNA pseudouridine(38/39) synthase" NARROW [EC:5.4.99.45] +synonym: "tRNA pseudouridine(55) synthase" NARROW [EC:5.4.99.25] +synonym: "tRNA pseudouridine(65) synthase" NARROW [EC:5.4.99.26] +synonym: "tRNA pseudouridylate synthase I activity" NARROW [EC:5.4.99.12] +synonym: "tRNA-pseudouridine synthase activity" EXACT [] +synonym: "tRNA-pseudouridine synthase I activity" NARROW [EC:5.4.99.12] +synonym: "tRNA-uridine isomerase activity" EXACT [] +synonym: "tRNA-uridine uracilmutase activity" EXACT [] +xref: EC:5.4.99.12 +xref: EC:5.4.99.25 +xref: EC:5.4.99.26 +xref: EC:5.4.99.27 +xref: EC:5.4.99.28 +xref: EC:5.4.99.42 +xref: EC:5.4.99.44 +xref: EC:5.4.99.45 +xref: MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN +is_a: GO:0009982 ! pseudouridine synthase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +created_by: hjd +creation_date: 2017-06-26T17:37:30Z + +[Term] +id: GO:0106030 +name: neuron projection fasciculation +namespace: biological_process +def: "The collection of neuronal projections into a bundle of rods, known as a fascicle." [GOC:aruk, GOC:bc., PMID:12761826] +is_a: GO:0031175 ! neuron projection development +created_by: hjd +creation_date: 2017-06-26T19:43:23Z + +[Term] +id: GO:0106032 +name: snRNA pseudouridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [PMID:28432181] +is_a: GO:0009982 ! pseudouridine synthase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: hjd +creation_date: 2017-06-28T17:44:20Z + +[Term] +id: GO:0106033 +name: spine synapse +namespace: cellular_component +def: "A type of synapse occurring between an axon and a dendritic spine." [PMID:15028757] +synonym: "dendritic spine synapse" EXACT [] +is_a: GO:0032279 ! asymmetric synapse +created_by: hjd +creation_date: 2017-07-05T19:20:48Z + +[Term] +id: GO:0106034 +name: protein maturation by [2Fe-2S] cluster transfer +namespace: biological_process +def: "The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein." [PMID:23615440] +is_a: GO:0097428 ! protein maturation by iron-sulfur cluster transfer +created_by: hjd +creation_date: 2017-07-07T17:24:59Z + +[Term] +id: GO:0106035 +name: protein maturation by [4Fe-4S] cluster transfer +namespace: biological_process +def: "The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein." [PMID:23615440] +is_a: GO:0097428 ! protein maturation by iron-sulfur cluster transfer +created_by: hjd +creation_date: 2017-07-07T17:26:10Z + +[Term] +id: GO:0106036 +name: assembly of apicomedial cortex actomyosin +namespace: biological_process +def: "A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin." [PMID:28263180] +is_a: GO:0030866 ! cortical actin cytoskeleton organization +is_a: GO:0031032 ! actomyosin structure organization +created_by: hjd +creation_date: 2017-07-12T16:57:06Z + +[Term] +id: GO:0106037 +name: apicomedial cortex +namespace: cellular_component +def: "The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell." [PMID:23831726, PMID:28263180] +synonym: "medioapical cortex" EXACT [] +is_a: GO:0045179 ! apical cortex +relationship: part_of GO:0045179 ! apical cortex +created_by: hjd +creation_date: 2017-07-12T16:59:52Z + +[Term] +id: GO:0106038 +name: obsolete vesicle assembly +namespace: biological_process +def: "OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050)." [GOC:aruk, GOC:bc, PMID:25898166] +comment: This term was made obsolete because it is an exact synonym of 'membrane budding'. +synonym: "vesicle biosynthesis" EXACT [] +synonym: "vesicle formation" EXACT [] +is_obsolete: true +created_by: hjd +creation_date: 2017-07-17T13:52:28Z + +[Term] +id: GO:0106039 +name: obsolete vesicle fusion involved in vesicle assembly +namespace: biological_process +def: "OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050)." [GOC:aruk, GOC:bc, PMID:25898166] +comment: This term was made obsolete becausethat 'fusion' should only be used for two membranes getting joined together, whereas in this case it would be one membrane 'closing/sealing up'. +is_obsolete: true +created_by: hjd +creation_date: 2017-07-17T13:56:31Z + +[Term] +id: GO:0106040 +name: regulation of GABA-A receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of GABA-A receptor activity." [PMID:24044036] +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004890 ! GABA-A receptor activity +relationship: regulates GO:0004890 ! GABA-A receptor activity +created_by: hjd +creation_date: 2017-07-27T18:47:02Z + +[Term] +id: GO:0106041 +name: positive regulation of GABA-A receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity." [PMID:24044036] +is_a: GO:0106040 ! regulation of GABA-A receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004890 ! GABA-A receptor activity +relationship: positively_regulates GO:0004890 ! GABA-A receptor activity +created_by: hjd +creation_date: 2017-07-27T18:51:30Z + +[Term] +id: GO:0106042 +name: negative regulation of GABA-A receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity." [PMID:24044036] +is_a: GO:0106040 ! regulation of GABA-A receptor activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004890 ! GABA-A receptor activity +relationship: negatively_regulates GO:0004890 ! GABA-A receptor activity +created_by: hjd +creation_date: 2017-07-27T18:55:03Z + +[Term] +id: GO:0106044 +name: guanine deglycation +namespace: biological_process +def: "The removal of a sugar or dicarbonyl from a glycated guanine." [PMID:28596309] +is_a: GO:0009117 ! nucleotide metabolic process +created_by: hjd +creation_date: 2017-08-01T18:15:28Z + +[Term] +id: GO:0106045 +name: guanine deglycation, methylglyoxal removal +namespace: biological_process +def: "The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine." [PMID:28596309] +is_a: GO:0106044 ! guanine deglycation +is_a: GO:0140041 ! cellular detoxification of methylglyoxal +created_by: hjd +creation_date: 2017-08-01T18:17:28Z + +[Term] +id: GO:0106046 +name: guanine deglycation, glyoxal removal +namespace: biological_process +def: "The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine." [PMID:28596309] +is_a: GO:0106044 ! guanine deglycation +created_by: hjd +creation_date: 2017-08-01T18:19:30Z + +[Term] +id: GO:0106047 +name: polyamine deacetylation +namespace: biological_process +def: "The modification of acetylpolyamine by the removal of acetyl groups." [PMID:28516954] +is_a: GO:0006595 ! polyamine metabolic process +is_a: GO:0098732 ! macromolecule deacylation +created_by: hjd +creation_date: 2017-08-01T18:36:46Z + +[Term] +id: GO:0106048 +name: spermidine deacetylation +namespace: biological_process +def: "The modification of acetylspermadine by the removal of acetyl groups." [PMID:28516954] +synonym: "N8-acetylspermidine deacetylation" EXACT [] +is_a: GO:0008216 ! spermidine metabolic process +is_a: GO:0106047 ! polyamine deacetylation +created_by: hjd +creation_date: 2017-08-01T18:39:17Z + +[Term] +id: GO:0106049 +name: regulation of cellular response to osmotic stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress." [PMID:10398679] +is_a: GO:0047484 ! regulation of response to osmotic stress +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071470 ! cellular response to osmotic stress +relationship: regulates GO:0071470 ! cellular response to osmotic stress +created_by: hjd +creation_date: 2017-08-04T14:53:47Z + +[Term] +id: GO:0106050 +name: tRNA 2'-O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide." [PMID:17242307] +is_a: GO:0008175 ! tRNA methyltransferase activity +is_a: GO:0062105 ! RNA 2'-O-methyltransferase activity +created_by: hjd +creation_date: 2017-08-11T20:30:31Z + +[Term] +id: GO:0106054 +name: tRNA U34 thiol-transferase activity +namespace: molecular_function +def: "Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+." [PMID:12549933, PMID:16387657] +synonym: "tRNA U34 2-thiouridylase" EXACT [] +synonym: "tRNA-specific 2-thiouridylase" RELATED [] +is_a: GO:0016783 ! sulfurtransferase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +relationship: part_of GO:0002098 ! tRNA wobble uridine modification +created_by: hjd +creation_date: 2017-09-05T19:10:12Z + +[Term] +id: GO:0106055 +name: mannosyl-oligosaccharide 1,2-alpha-mannosidase complex +namespace: cellular_component +def: "A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide." [GOC:bhm, PMID:21700223] +comment: An example is MNL1 (P38888) in Saccharomyces cerevisiae. PMID:19124653 (by physical interaction evidence). +xref: IntAct:EBI-16411902 +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005788 ! endoplasmic reticulum lumen +created_by: hjd +creation_date: 2017-09-14T15:23:28Z + +[Term] +id: GO:0106056 +name: regulation of calcineurin-mediated signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling." [PMID:25081204] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097720 ! calcineurin-mediated signaling +relationship: regulates GO:0097720 ! calcineurin-mediated signaling +created_by: hjd +creation_date: 2017-09-18T16:44:05Z + +[Term] +id: GO:0106057 +name: negative regulation of calcineurin-mediated signaling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling." [PMID:25081204] +is_a: GO:0050849 ! negative regulation of calcium-mediated signaling +is_a: GO:0106056 ! regulation of calcineurin-mediated signaling +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0097720 ! calcineurin-mediated signaling +relationship: negatively_regulates GO:0097720 ! calcineurin-mediated signaling +created_by: hjd +creation_date: 2017-09-18T16:50:11Z + +[Term] +id: GO:0106058 +name: positive regulation of calcineurin-mediated signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling." [PMID:25081204] +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +is_a: GO:0106056 ! regulation of calcineurin-mediated signaling +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0097720 ! calcineurin-mediated signaling +relationship: positively_regulates GO:0097720 ! calcineurin-mediated signaling +created_by: hjd +creation_date: 2017-09-18T16:57:06Z + +[Term] +id: GO:0106059 +name: tRNA (cytidine56-2'-O)-methyltransferase +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA." [EC:2.1.1.206] +is_a: GO:0052666 ! tRNA (cytosine-2'-O-)-methyltransferase activity +created_by: hjd +creation_date: 2017-10-05T19:02:22Z + +[Term] +id: GO:0106060 +name: regulation of exit from meiosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exit from mitosis." [GOC:al, PMID:11493649] +is_a: GO:1901993 ! regulation of meiotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990947 ! exit from meiosis +relationship: regulates GO:1990947 ! exit from meiosis +created_by: hjd +creation_date: 2017-10-18T16:48:01Z + +[Term] +id: GO:0106061 +name: negative regulation of exit from meiosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis." [GOC:al, PMID:11493649] +is_a: GO:0106060 ! regulation of exit from meiosis +is_a: GO:1901994 ! negative regulation of meiotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990947 ! exit from meiosis +relationship: negatively_regulates GO:1990947 ! exit from meiosis +created_by: hjd +creation_date: 2017-10-18T16:51:15Z + +[Term] +id: GO:0106062 +name: positive regulation of exit from meiosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exit from meiosis." [GOC:al, PMID:11493649] +is_a: GO:0106060 ! regulation of exit from meiosis +is_a: GO:1901995 ! positive regulation of meiotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990947 ! exit from meiosis +relationship: positively_regulates GO:1990947 ! exit from meiosis +created_by: hjd +creation_date: 2017-10-18T16:57:01Z + +[Term] +id: GO:0106063 +name: G protein-coupled folate receptor activity +namespace: molecular_function +def: "Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity." [PMID:26906738] +synonym: "G-protein coupled folate receptor activity" EXACT [] +synonym: "G-protein coupled folic acid receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +created_by: hjd +creation_date: 2017-10-27T17:10:07Z + +[Term] +id: GO:0106064 +name: regulation of cobalamin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [PMID:29056341] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009235 ! cobalamin metabolic process +relationship: regulates GO:0009235 ! cobalamin metabolic process +created_by: hjd +creation_date: 2017-10-27T17:33:05Z + +[Term] +id: GO:0106068 +name: SUMO ligase complex +namespace: cellular_component +def: "A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex." [PMID:16847351] +synonym: "SUMO transferase complex" EXACT [] +synonym: "SUMO-protein ligase complex" EXACT [] +synonym: "Sumoylation complex" EXACT [] +is_a: GO:1990234 ! transferase complex +created_by: hjd +creation_date: 2017-11-22T18:46:00Z + +[Term] +id: GO:0106069 +name: synapsis initiation complex +namespace: cellular_component +def: "A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase." [PMID:16847351] +xref: IntAct:EBI-16586568 +is_a: GO:0106068 ! SUMO ligase complex +relationship: part_of GO:0000794 ! condensed nuclear chromosome +created_by: hjd +creation_date: 2017-11-22T18:50:26Z + +[Term] +id: GO:0106070 +name: regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway." [GOC:hjd, PMID:19246489] +synonym: "regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0043949 ! regulation of cAMP-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +relationship: regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +created_by: hjd +creation_date: 2017-11-28T18:28:22Z + +[Term] +id: GO:0106071 +name: positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway." [GOC:hjd, PMID:19246489] +synonym: "positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0043950 ! positive regulation of cAMP-mediated signaling +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0106070 ! regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +relationship: positively_regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +created_by: hjd +creation_date: 2017-11-28T18:38:52Z + +[Term] +id: GO:0106072 +name: negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway." [GOC:hjd, PMID:19246489] +synonym: "negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0043951 ! negative regulation of cAMP-mediated signaling +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0106070 ! regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +relationship: negatively_regulates GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway +created_by: hjd +creation_date: 2017-11-28T18:41:31Z + +[Term] +id: GO:0106073 +name: dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity +namespace: molecular_function +def: "Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol." [GOC:ha, PMID:9597543] +xref: EC:2.4.1.256 +is_a: GO:0046527 ! glucosyltransferase activity +created_by: hjd +creation_date: 2017-11-28T19:16:37Z + +[Term] +id: GO:0106074 +name: aminoacyl-tRNA metabolism involved in translational fidelity +namespace: biological_process +def: "Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation." [GOC:hjd] +synonym: "aminoacyl-tRNA correction" RELATED [] +synonym: "aminoacyl-tRNA editin" RELATED [] +synonym: "aminoacyl-tRNA proofreading" RELATED [] +is_a: GO:0006399 ! tRNA metabolic process +is_a: GO:0006450 ! regulation of translational fidelity +created_by: hjd +creation_date: 2017-11-29T17:48:39Z + +[Term] +id: GO:0106075 +name: peptide N-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide." [PMID:29211711] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: hjd +creation_date: 2017-12-15T18:23:58Z + +[Term] +id: GO:0106076 +name: peptide-lysine-N-succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide." [PMID:29211711] +is_a: GO:0106075 ! peptide N-succinyltransferase activity +created_by: hjd +creation_date: 2017-12-15T18:25:16Z + +[Term] +id: GO:0106077 +name: histone succinylation +namespace: biological_process +def: "The modification of a histone by the addition of an succinyl group." [PMID:29211711] +is_a: GO:0018335 ! protein succinylation +created_by: hjd +creation_date: 2017-12-15T18:27:16Z + +[Term] +id: GO:0106078 +name: histone succinyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone." [PMID:29211711] +is_a: GO:0106075 ! peptide N-succinyltransferase activity +created_by: hjd +creation_date: 2017-12-15T18:29:40Z + +[Term] +id: GO:0106080 +name: GATOR1 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the GATOR1 complex." [PMID:28199306] +is_a: GO:0044877 ! protein-containing complex binding +created_by: hjd +creation_date: 2017-12-22T14:49:54Z + +[Term] +id: GO:0106081 +name: maltose import across plasma membrane +namespace: biological_process +def: "The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol." [PMID:11136464] +is_a: GO:0098704 ! carbohydrate import across plasma membrane +is_a: GO:1904981 ! maltose transmembrane transport +created_by: hjd +creation_date: 2017-12-28T18:14:16Z + +[Term] +id: GO:0106082 +name: sucrose import across plasma membrane +namespace: biological_process +def: "The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol." [PMID:11136464] +is_a: GO:0098704 ! carbohydrate import across plasma membrane +is_a: GO:1904982 ! sucrose transmembrane transport +created_by: hjd +creation_date: 2017-12-28T18:16:29Z + +[Term] +id: GO:0106083 +name: nuclear membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of the nuclear membrane." [GOC:lnp, PMID:28356353] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005635 ! nuclear envelope +relationship: part_of GO:0031224 ! intrinsic component of membrane +created_by: hjd +creation_date: 2018-01-05T19:51:26Z + +[Term] +id: GO:0106084 +name: nuclear membrane mitotic spindle pole body tethering complex +namespace: cellular_component +def: "A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane." [GOC:lnp, PMID:28356353] +comment: In S. cerevisae Mps2-Bpb1 is the membrane anchor sub complex and Spc29 is the spindle pole body linker molecule. +synonym: "Mps2-Bbp1-Spc29 complex" RELATED [] +xref: IntAct:EBI-16412392 +is_a: GO:0106083 ! nuclear membrane protein complex +created_by: hjd +creation_date: 2018-01-05T19:55:37Z + +[Term] +id: GO:0106088 +name: regulation of cell adhesion involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325] +is_a: GO:0030155 ! regulation of cell adhesion +is_a: GO:1903670 ! regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +relationship: regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +created_by: hjd +creation_date: 2018-01-22T18:24:12Z + +[Term] +id: GO:0106089 +name: negative regulation of cell adhesion involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325] +is_a: GO:0007162 ! negative regulation of cell adhesion +is_a: GO:0106088 ! regulation of cell adhesion involved in sprouting angiogenesis +is_a: GO:1903671 ! negative regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +relationship: negatively_regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +created_by: hjd +creation_date: 2018-01-22T18:28:08Z + +[Term] +id: GO:0106090 +name: positive regulation of cell adhesion involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325] +is_a: GO:0045785 ! positive regulation of cell adhesion +is_a: GO:0106088 ! regulation of cell adhesion involved in sprouting angiogenesis +is_a: GO:1903672 ! positive regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +relationship: positively_regulates GO:0120078 ! cell adhesion involved in sprouting angiogenesis +created_by: hjd +creation_date: 2018-01-22T18:31:02Z + +[Term] +id: GO:0106091 +name: glial cell projection elongation +namespace: biological_process +def: "The process of creating an elongation or projection from a glial cell." [GOC:ha, PMID:27131624] +is_a: GO:0048858 ! cell projection morphogenesis +relationship: part_of GO:0021782 ! glial cell development +created_by: hjd +creation_date: 2018-01-26T19:40:19Z + +[Term] +id: GO:0106092 +name: glial cell projection elongation involved in axon ensheathment +namespace: biological_process +def: "The extension of a glial cell process or projection to wrap around an axon." [GOC:ha, PMID:27131624] +is_a: GO:0008366 ! axon ensheathment +is_a: GO:0106091 ! glial cell projection elongation +created_by: hjd +creation_date: 2018-01-26T19:43:00Z + +[Term] +id: GO:0106093 +name: EDS1 disease-resistance complex +namespace: cellular_component +def: "A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes." [GOC:bhm, PMID:11574472, PMID:16040633] +comment: Interacts with the R genes triggering ETI and systemic resistance. +synonym: "EDS1-PAD4 complex" NARROW [] +synonym: "EDS1-PAD4-SAG101 complex" NARROW [] +synonym: "EDS1-SAG101 complex" NARROW [] +xref: IntAct:EBI-16422538 +xref: IntAct:EBI-16423002 +xref: IntAct:EBI-16423498 +xref: IntAct:EBI-16748636 +xref: IntAct:EBI-16748699 +xref: IntAct:EBI-16748728 +is_a: GO:0032991 ! protein-containing complex +created_by: hjd +creation_date: 2018-01-29T20:02:47Z + +[Term] +id: GO:0106094 +name: nuclear membrane microtubule tethering complex +namespace: cellular_component +def: "A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules." [GOC:vw, PMID:19225124] +is_a: GO:0106083 ! nuclear membrane protein complex +created_by: hjd +creation_date: 2018-02-02T18:58:35Z + +[Term] +id: GO:0106095 +name: m7G(5')pppN diphosphatase complex +namespace: cellular_component +def: "A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide." [GOC:lnp, PMID:22985415, PMID:26258763] +synonym: "7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme" EXACT [] +synonym: "DCS1 decapping scavenger complex" EXACT [] +synonym: "M(7)G(5')pppN pyrophosphatase enzyme" EXACT [] +synonym: "m7G(5')pppN diphosphatase enzyme" EXACT [] +synonym: "m7G(5')pppN pyrophosphatase enzyme" EXACT [] +xref: IntAct:EBI-15484673 +is_a: GO:0034518 ! RNA cap binding complex +is_a: GO:1903293 ! phosphatase complex +created_by: hjd +creation_date: 2018-02-07T17:52:03Z + +[Term] +id: GO:0106096 +name: response to ceramide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus." [PMID:18006463] +is_a: GO:0033993 ! response to lipid +created_by: hjd +creation_date: 2018-02-12T19:48:43Z + +[Term] +id: GO:0106097 +name: cellular response to ceramide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus." [PMID:18006463] +is_a: GO:0071396 ! cellular response to lipid +created_by: hjd +creation_date: 2018-02-12T19:52:55Z + +[Term] +id: GO:0106098 +name: NAGS/NAGK complex +namespace: cellular_component +def: "A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate." [GOC:lnp, PMID:11553611] +xref: IntAct:EBI-15101175 +is_a: GO:0031248 ! protein acetyltransferase complex +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +is_a: GO:0098798 ! mitochondrial protein complex +relationship: part_of GO:0005759 ! mitochondrial matrix +created_by: hjd +creation_date: 2018-02-15T00:22:31Z + +[Term] +id: GO:0106099 +name: 2-keto-3-deoxy-L-rhamnonate aldolase activity +namespace: molecular_function +def: "Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde." [EC:4.1.2.53, GOC:imk, PMID:18754683] +xref: EC:4.1.2.53 +is_a: GO:0016832 ! aldehyde-lyase activity +created_by: hjd +creation_date: 2018-02-15T16:12:17Z + +[Term] +id: GO:0106100 +name: beta-pinacene synthase activity +namespace: molecular_function +def: "Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene." [GOC:rjd, PMID:28696553] +is_a: GO:0010333 ! terpene synthase activity +created_by: hjd +creation_date: 2018-02-15T16:51:59Z + +[Term] +id: GO:0106101 +name: ER-dependent peroxisome localization +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum." [GOC:pga, PMID:19479899, PMID:26408931] +is_a: GO:0072662 ! protein localization to peroxisome +created_by: hjd +creation_date: 2018-02-15T17:54:20Z + +[Term] +id: GO:0106103 +name: COPII vesicles tethering complex +namespace: cellular_component +def: "A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae." [GOC:lnp, PMID:21482742, PMID:9628863] +synonym: "Bug1-Grh1 complex" NARROW [] +synonym: "GRASP65-GM130 complex" EXACT [] +xref: IntAct:EBI-14061261 +is_a: GO:0098796 ! membrane protein complex +is_a: GO:0099023 ! vesicle tethering complex +relationship: part_of GO:0033106 ! cis-Golgi network membrane +created_by: hjd +creation_date: 2018-02-15T23:36:12Z + +[Term] +id: GO:0106104 +name: regulation of glutamate receptor clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamate receptor clustering." [GOC:ha, PMID:28455372] +is_a: GO:0050807 ! regulation of synapse organization +is_a: GO:1903909 ! regulation of receptor clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097688 ! glutamate receptor clustering +relationship: regulates GO:0097688 ! glutamate receptor clustering +created_by: hjd +creation_date: 2018-03-06T15:54:33Z + +[Term] +id: GO:0106105 +name: Ala-tRNA(Thr) hydrolase activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of misacylated ala-tRNA(thr)." [PMID:29410408] +synonym: "L-alanyl-tRNA(Thr) deacylase" EXACT [] +is_a: GO:0002161 ! aminoacyl-tRNA editing activity +created_by: hjd +creation_date: 2018-03-14T22:03:29Z + +[Term] +id: GO:0106106 +name: cold-induced thermogenesis +namespace: biological_process +def: "The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature." [PMID:27876809] +synonym: "CIT" RELATED [] +is_a: GO:0001659 ! temperature homeostasis +is_a: GO:1990845 ! adaptive thermogenesis +created_by: hjd +creation_date: 2018-03-21T20:30:52Z + +[Term] +id: GO:0106107 +name: regulation of (R)-mevalonic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +relationship: regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +created_by: hjd +creation_date: 2018-03-27T14:08:59Z + +[Term] +id: GO:0106108 +name: negative regulation of (R)-mevalonic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:0106107 ! regulation of (R)-mevalonic acid biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +relationship: negatively_regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +created_by: hjd +creation_date: 2018-03-27T14:15:55Z + +[Term] +id: GO:0106109 +name: positive regulation of (R)-mevalonic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:0106107 ! regulation of (R)-mevalonic acid biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +relationship: positively_regulates GO:1901737 ! (R)-mevalonic acid biosynthetic process +created_by: hjd +creation_date: 2018-03-27T14:20:47Z + +[Term] +id: GO:0106110 +name: vomitoxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats." [http://www.inchem.org/documents/jecfa/jecmono/v47je05.htm, https://doi.org/10.1007/BF03356188, PMID:19333439, PMID:25680507, PMID:25758923, PMID:8637056] +synonym: "deoxynivalenol biosynthetic process" EXACT [] +synonym: "DON biosynthetic process" EXACT [] +synonym: "vomitoxin anabolism" EXACT [] +synonym: "vomitoxin biosynthesis" EXACT [] +synonym: "vomitoxin formation" EXACT [] +synonym: "vomitoxin synthesis" EXACT [] +is_a: GO:0043386 ! mycotoxin biosynthetic process +created_by: hjd +creation_date: 2018-04-16T19:06:06Z + +[Term] +id: GO:0106111 +name: regulation of mitotic cohesin ssDNA (lagging strand) loading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading." [PMID:29358048] +is_a: GO:1905405 ! regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +relationship: regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +created_by: hjd +creation_date: 2018-04-18T14:36:47Z + +[Term] +id: GO:0106112 +name: negative regulation of mitotic cohesin ssDNA (lagging strand) loading +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading." [PMID:29358048] +is_a: GO:0106111 ! regulation of mitotic cohesin ssDNA (lagging strand) loading +is_a: GO:1905412 ! negative regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +relationship: negatively_regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +created_by: hjd +creation_date: 2018-04-18T14:41:50Z + +[Term] +id: GO:0106113 +name: positive regulation of mitotic cohesin ssDNA (lagging strand) loading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading." [PMID:29358048] +is_a: GO:0106111 ! regulation of mitotic cohesin ssDNA (lagging strand) loading +is_a: GO:1905406 ! positive regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +relationship: positively_regulates GO:0062022 ! mitotic cohesin ssDNA (lagging strand) loading +created_by: hjd +creation_date: 2018-04-18T14:46:03Z + +[Term] +id: GO:0106114 +name: regulation of mitotic cohesin dsDNA (leading strand) loading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading." [PMID:29358048] +is_a: GO:1905405 ! regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +relationship: regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +created_by: hjd +creation_date: 2018-04-18T14:48:13Z + +[Term] +id: GO:0106115 +name: negative regulation of mitotic cohesin dsDNA (leading strand) loading +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading." [PMID:29358048] +is_a: GO:0106114 ! regulation of mitotic cohesin dsDNA (leading strand) loading +is_a: GO:1905412 ! negative regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +relationship: negatively_regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +created_by: hjd +creation_date: 2018-04-18T14:50:12Z + +[Term] +id: GO:0106116 +name: positive regulation of mitotic cohesin dsDNA (leading strand) loading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading." [PMID:29358048] +is_a: GO:0106114 ! regulation of mitotic cohesin dsDNA (leading strand) loading +is_a: GO:1905406 ! positive regulation of mitotic cohesin loading +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +relationship: positively_regulates GO:0062021 ! mitotic cohesin dsDNA (leading strand) loading +created_by: hjd +creation_date: 2018-04-18T14:52:21Z + +[Term] +id: GO:0106117 +name: acidocalcisome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations." [GO:0020022, PMID:25964650, PMID:26523947] +synonym: "acidocalcisome biogenesis" EXACT [] +synonym: "acidocalcisome organisation" EXACT [] +synonym: "acidocalcisome organization and biogenesis" EXACT [] +synonym: "metachromatic granule organization" EXACT [] +synonym: "polyphosphate vacuole organization" RELATED [] +synonym: "volutin granule organization" EXACT [] +is_a: GO:0006996 ! organelle organization +created_by: hjd +creation_date: 2018-04-19T17:18:01Z + +[Term] +id: GO:0106118 +name: regulation of sterol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a sterol biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310] +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0016126 ! sterol biosynthetic process +relationship: regulates GO:0016126 ! sterol biosynthetic process +created_by: hjd +creation_date: 2018-04-19T17:41:06Z + +[Term] +id: GO:0106119 +name: negative regulation of sterol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0106118 ! regulation of sterol biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0016126 ! sterol biosynthetic process +relationship: negatively_regulates GO:0016126 ! sterol biosynthetic process +created_by: hjd +creation_date: 2018-04-19T17:44:46Z + +[Term] +id: GO:0106120 +name: positive regulation of sterol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0106118 ! regulation of sterol biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0016126 ! sterol biosynthetic process +relationship: positively_regulates GO:0016126 ! sterol biosynthetic process +created_by: hjd +creation_date: 2018-04-19T17:48:21Z + +[Term] +id: GO:0106121 +name: positive regulation of cobalamin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process." [PMID:29056341] +is_a: GO:0046136 ! positive regulation of vitamin metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:0106064 ! regulation of cobalamin metabolic process +is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0009235 ! cobalamin metabolic process +relationship: positively_regulates GO:0009235 ! cobalamin metabolic process +created_by: hjd +creation_date: 2018-05-01T18:07:12Z + +[Term] +id: GO:0106122 +name: negative regulation of cobalamin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process." [PMID:29056341] +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:0106064 ! regulation of cobalamin metabolic process +is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0009235 ! cobalamin metabolic process +relationship: negatively_regulates GO:0009235 ! cobalamin metabolic process +created_by: hjd +creation_date: 2018-05-01T18:12:48Z + +[Term] +id: GO:0106123 +name: reservosome +namespace: cellular_component +def: "A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes." [GOC:ach, PMID:12204365, PMID:15521631, PMID:1845219, PMID:19288526, PMID:21818313, PMID:22425988] +is_a: GO:0000322 ! storage vacuole +is_a: GO:0000323 ! lytic vacuole +created_by: hjd +creation_date: 2018-05-03T17:48:59Z + +[Term] +id: GO:0106124 +name: reservosome lumen +namespace: cellular_component +def: "The volume enclosed by the membranes of a reservosome." [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0106123 ! reservosome +created_by: hjd +creation_date: 2018-05-03T17:54:46Z + +[Term] +id: GO:0106125 +name: reservosome matrix +namespace: cellular_component +def: "A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome." [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0106123 ! reservosome +created_by: hjd +creation_date: 2018-05-03T18:00:03Z + +[Term] +id: GO:0106126 +name: reservosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a reservosome." [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0106123 ! reservosome +created_by: hjd +creation_date: 2018-05-03T18:01:26Z + +[Term] +id: GO:0106128 +name: negative regulation of store-operated calcium entry +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23447642] +is_a: GO:0051926 ! negative regulation of calcium ion transport +is_a: GO:2001256 ! regulation of store-operated calcium entry +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0002115 ! store-operated calcium entry +relationship: negatively_regulates GO:0002115 ! store-operated calcium entry +created_by: hjd +creation_date: 2018-05-10T18:59:12Z + +[Term] +id: GO:0106129 +name: positive regulation of store-operated calcium entry +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of store-operated calcium entry." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23447642] +is_a: GO:0051928 ! positive regulation of calcium ion transport +is_a: GO:2001256 ! regulation of store-operated calcium entry +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0002115 ! store-operated calcium entry +relationship: positively_regulates GO:0002115 ! store-operated calcium entry +created_by: hjd +creation_date: 2018-05-10T19:02:40Z + +[Term] +id: GO:0106130 +name: purine phosphoribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate." [PMID:5123876] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +created_by: hjd +creation_date: 2018-06-14T17:38:53Z + +[Term] +id: GO:0106134 +name: positive regulation of cardiac muscle cell contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction." [PMID:19525381] +is_a: GO:0060452 ! positive regulation of cardiac muscle contraction +is_a: GO:0086004 ! regulation of cardiac muscle cell contraction +is_a: GO:1903116 ! positive regulation of actin filament-based movement +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0086003 ! cardiac muscle cell contraction +relationship: positively_regulates GO:0086003 ! cardiac muscle cell contraction +created_by: hjd +creation_date: 2018-07-26T16:05:16Z + +[Term] +id: GO:0106135 +name: negative regulation of cardiac muscle cell contraction +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction." [PMID:19525381] +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0055118 ! negative regulation of cardiac muscle contraction +is_a: GO:0086004 ! regulation of cardiac muscle cell contraction +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0086003 ! cardiac muscle cell contraction +relationship: negatively_regulates GO:0086003 ! cardiac muscle cell contraction +created_by: hjd +creation_date: 2018-07-26T16:10:17Z + +[Term] +id: GO:0106136 +name: lectin-induced modified bacterial internalization +namespace: biological_process +def: "The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:rjd, PMID:30049880] +synonym: "LIMBI" EXACT [] +is_a: GO:0051702 ! interaction with symbiont +created_by: hjd +creation_date: 2018-08-09T17:27:18Z + +[Term] +id: GO:0106137 +name: IkappaB kinase complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the IkappaB kinase complex." [GOC:pga, PMID:12492477] +is_a: GO:0044877 ! protein-containing complex binding +created_by: hjd +creation_date: 2018-08-15T14:05:10Z + +[Term] +id: GO:0106138 +name: Sec61 translocon complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Sec61 translocon complex." [GOC:pga, PMID:9792704] +is_a: GO:0044877 ! protein-containing complex binding +created_by: hjd +creation_date: 2018-08-15T14:50:29Z + +[Term] +id: GO:0106139 +name: symbiont cell surface +namespace: cellular_component +def: "The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:rjd, PMID:30049880] +synonym: "endosymbiont cell surface" EXACT [] +is_a: GO:0044217 ! other organism part +relationship: part_of GO:0044216 ! other organism cell +created_by: hjd +creation_date: 2018-08-15T18:56:57Z + +[Term] +id: GO:0106140 +name: P-TEFb complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the P-TEFb complex." [GOC:pga, PMID:18391197] +is_a: GO:0044877 ! protein-containing complex binding +created_by: hjd +creation_date: 2018-08-17T18:17:50Z + +[Term] +id: GO:0106141 +name: flavin prenyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate." [GOC:imk, PMID:26083743] +xref: EC:2.5.1.129 +xref: RHEA:37743 +is_a: GO:0004659 ! prenyltransferase activity +created_by: hjd +creation_date: 2018-08-17T18:50:00Z + +[Term] +id: GO:0106142 +name: rRNA (adenine-N1-)-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA." [EC:2.1.1.287, PMID:23180764] +comment: The m(1)A modification at position 645 in the large rRNA is highly conserved in eukaryotes. +synonym: "25S rRNA (adenine(645)-N(1))-methyltransferase" EXACT [EC:2.1.1.287] +synonym: "25S rRNA m(1)A(645) methyltransferase" EXACT [EC:2.1.1.287] +xref: EC:2.1.1.287 +is_a: GO:0016433 ! rRNA (adenine) methyltransferase activity +created_by: hjd +creation_date: 2018-08-22T20:13:21Z + +[Term] +id: GO:0106143 +name: tRNA (m7G46) methyltransferase complex +namespace: cellular_component +def: "A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat)." [GOC:vw, PMID:15811913, PMID:1738232, PMID:18164779, PMID:18184583] +synonym: "Trm8-Trm82 complex" EXACT [] +synonym: "tRNA (m7G46) methyltransferase" EXACT [] +synonym: "tRNA m7G methylation complex" EXACT [] +is_a: GO:0043527 ! tRNA methyltransferase complex +created_by: hjd +creation_date: 2018-09-07T14:53:29Z + +[Term] +id: GO:0106144 +name: fraxetin 5-hydroxylase activity +namespace: molecular_function +def: "Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20." [GOC:lr, PMID:29581584] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: hjd +creation_date: 2018-09-07T18:24:41Z + +[Term] +id: GO:0106145 +name: scopoletin 8-hydroxylase activity +namespace: molecular_function +def: "Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2)." [GOC:lr, PMID:29361149, PMID:29581584] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: hjd +creation_date: 2018-09-07T18:28:16Z + +[Term] +id: GO:0106146 +name: sideretin biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sideretin." [GOC:lr, PMID:29581584] +is_a: GO:0009805 ! coumarin biosynthetic process +created_by: hjd +creation_date: 2018-09-07T18:31:30Z + +[Term] +id: GO:0106147 +name: fraxetin biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fraxetin." [GOC:lr, PMID:29581584] +is_a: GO:0009805 ! coumarin biosynthetic process +created_by: hjd +creation_date: 2018-09-07T18:32:47Z + +[Term] +id: GO:0106148 +name: 4-hydroxyindole-3- carbonyl nitrile biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside." [GOC:lr, PMID:26352477] +is_a: GO:0019756 ! cyanogenic glycoside biosynthetic process +created_by: hjd +creation_date: 2018-09-10T19:42:16Z + +[Term] +id: GO:0106149 +name: indole-3-carbonyl nitrile 4-hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP(+) + H20." [GOC:lr, PMID:26352477] +is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +created_by: hjd +creation_date: 2018-09-10T19:44:15Z + +[Term] +id: GO:0106150 +name: zearalenone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals." [GOC:ach, PMID:16517624, PMID:20578001] +is_a: GO:0033068 ! macrolide biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +created_by: hjd +creation_date: 2018-09-14T17:08:18Z + +[Term] +id: GO:0106151 +name: CNBH domain intrinsic ligand binding +namespace: molecular_function +def: "Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide." [GOC:cvs, PMID:27025590, PMID:29567795] +comment: It is unclear if the motif bound by CNBHD is a specific motif or just a beta sheet with the appropriate amino acids. +is_a: GO:0005515 ! protein binding +created_by: hjd +creation_date: 2018-09-18T20:47:35Z + +[Term] +id: GO:0106153 +name: phosphorylated histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone in which a residue has been modified by phosphorylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes." [GOC:mah, PMID:20679485] +is_a: GO:0042393 ! histone binding +is_a: GO:0140031 ! phosphorylation-dependent protein binding +created_by: hjd +creation_date: 2018-09-19T17:23:06Z + +[Term] +id: GO:0106154 +name: perithecium formation +namespace: biological_process +def: "The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck." [DOI:10.1007/978-3-642-00286-1_2, GOC:ach, PMID:19547974, PMID:21134480, PMID:25311923] +is_a: GO:0120165 ! perithecium development +created_by: hjd +creation_date: 2018-09-19T19:12:53Z + +[Term] +id: GO:0106155 +name: peptidyl-lysine 3-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2." [GOC:al, PMID:29915238] +xref: RHEA:57153 +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: hjd +creation_date: 2018-11-15T20:09:45Z + +[Term] +id: GO:0106156 +name: peptidyl-lysine 4-dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2." [GOC:pde, PMID:24486019] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: hjd +creation_date: 2018-11-26T14:59:18Z + +[Term] +id: GO:0106157 +name: peptidyl-arginine 3-dioxygenase activity +namespace: molecular_function +def: "Proposed def: Catalysis of the reaction: protein L-arginie + 2-oxoglutarate + O2 = protein 3-hydroxy-L-arginine + succinate + CO2." [GOC:pde, PMID:29563586] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +created_by: hjd +creation_date: 2018-11-26T15:05:57Z + +[Term] +id: GO:0106158 +name: glycero-3-phosphocholine acyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine." [PMID:18430972, PMID:27758859] +synonym: "glycero-3-phosphocholine acyltransferase activity" RELATED [] +synonym: "glycerophosphocholine O-acyltransferase activity" RELATED [] +synonym: "GPCAT activity" RELATED [] +xref: BRENDA:EC2.3.1.B36 +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: hjd +creation_date: 2018-11-26T21:21:03Z + +[Term] +id: GO:0106159 +name: regulation of small RNA loading onto RISC +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent small RNA loading onto RISC." [GOC:ha, PMID:29775584] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0060966 ! regulation of gene silencing by RNA +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0070922 ! small RNA loading onto RISC +relationship: regulates GO:0070922 ! small RNA loading onto RISC +created_by: hjd +creation_date: 2018-11-30T15:38:50Z + +[Term] +id: GO:0106160 +name: negative regulation of small RNA loading onto RISC +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC." [GOC:ha, PMID:29775584] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0060967 ! negative regulation of gene silencing by RNA +is_a: GO:0106159 ! regulation of small RNA loading onto RISC +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0070922 ! small RNA loading onto RISC +relationship: negatively_regulates GO:0070922 ! small RNA loading onto RISC +created_by: hjd +creation_date: 2018-11-30T15:42:16Z + +[Term] +id: GO:0106161 +name: positive regulation of small RNA loading onto RISC +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC." [GOC:ha, PMID:29775584] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0106159 ! regulation of small RNA loading onto RISC +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0070922 ! small RNA loading onto RISC +relationship: positively_regulates GO:0070922 ! small RNA loading onto RISC +created_by: hjd +creation_date: 2018-11-30T15:45:53Z + +[Term] +id: GO:0106162 +name: mRNA N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H(+) + phosphate." [GOC:sp, PMID:30449621] +xref: RHEA:58480 +is_a: GO:0008080 ! N-acetyltransferase activity +created_by: hjd +creation_date: 2018-12-18T19:19:06Z + +[Term] +id: GO:0106163 +name: regulation of exonucleolytic catabolism of deadenylated mRNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay." [GOC:vw, PMID:30601114] +is_a: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +relationship: regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +created_by: hjd +creation_date: 2019-01-15T15:33:08Z + +[Term] +id: GO:0106164 +name: positive regulation of exonucleolytic catabolism of deadenylated mRNA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay." [GOC:vw, PMID:30601114] +is_a: GO:0106163 ! regulation of exonucleolytic catabolism of deadenylated mRNA +is_a: GO:1900153 ! positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +relationship: positively_regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +created_by: hjd +creation_date: 2019-01-15T15:39:19Z + +[Term] +id: GO:0106165 +name: negative regulation of exonucleolytic catabolism of deadenylated mRNA +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay." [GOC:vw, PMID:30601114] +is_a: GO:0106163 ! regulation of exonucleolytic catabolism of deadenylated mRNA +is_a: GO:1900152 ! negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +relationship: negatively_regulates GO:0043928 ! exonucleolytic catabolism of deadenylated mRNA +created_by: hjd +creation_date: 2019-01-15T15:42:13Z + +[Term] +id: GO:0106166 +name: spindle pole body-nuclear membrane anchor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body." [GOC:vw, PMID:9763447] +synonym: "nuclear membrane-spindle pole body anchor activity" EXACT [] +synonym: "spindle pole body anchor" EXACT [] +synonym: "spindle pole body nuclear membrane anchor activity" EXACT [] +is_a: GO:0043495 ! protein-membrane adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19119 xsd:anyURI +created_by: hjd +creation_date: 2019-01-18T15:57:42Z + +[Term] +id: GO:0106167 +name: extracellular ATP signaling +namespace: biological_process +def: "A series of molecular signals mediated by the detection of extracellular ATP." [GOC:tb, PMID:12948585, PMID:20817461, PMID:29274390] +is_a: GO:0007165 ! signal transduction +is_a: GO:0071318 ! cellular response to ATP +created_by: hjd +creation_date: 2019-02-06T19:21:44Z + +[Term] +id: GO:0106172 +name: COPI-coated vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a COPI-coated endocytic vesicle." [GOC:pde, PMID:29535154] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +relationship: part_of GO:0030137 ! COPI-coated vesicle +created_by: hjd +creation_date: 2019-02-11T18:04:08Z + +[Term] +id: GO:0106173 +name: COPII-coated vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a COPII-coated endocytic vesicle." [GOC:pde, PMID:21172817] +is_a: GO:0060205 ! cytoplasmic vesicle lumen +created_by: hjd +creation_date: 2019-02-11T18:16:22Z + +[Term] +id: GO:0106174 +name: phagolysosome vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a phagolysosome." [GOC:pde, PMID:29471269] +is_a: GO:0005775 ! vacuolar lumen +is_a: GO:0060205 ! cytoplasmic vesicle lumen +is_a: GO:0097013 ! phagocytic vesicle lumen +relationship: part_of GO:0032010 ! phagolysosome +created_by: hjd +creation_date: 2019-02-11T19:10:46Z + +[Term] +id: GO:0106175 +name: phagolysosome vesicle membrane +namespace: cellular_component +def: "The lipid bylayer surrounding a phagolysosome." [GOC:pde, PMID:29471269] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +relationship: part_of GO:0032010 ! phagolysosome +created_by: hjd +creation_date: 2019-02-11T19:12:53Z + +[Term] +id: GO:0106176 +name: clathrin-coated endocytic vesicle lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a clathrin-coated endocytic vesicle." [GOC:pde, PMID:2516741] +is_a: GO:0071682 ! endocytic vesicle lumen +relationship: part_of GO:0045334 ! clathrin-coated endocytic vesicle +created_by: hjd +creation_date: 2019-02-12T15:44:51Z + +[Term] +id: GO:0106177 +name: cyclic-GMP-AMP hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP." [GOC:sp, PMID:25344812, RHEA:58808] +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides +created_by: hjd +creation_date: 2019-03-07T21:06:24Z + +[Term] +id: GO:0106178 +name: obsolete translocase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:41:06Z + +[Term] +id: GO:0106179 +name: obsolete translocase activity acting on inorganic cations and their chelates +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.2 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:45:41Z + +[Term] +id: GO:0106180 +name: obsolete translocase activty of hydrons +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance)." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.1 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:48:44Z + +[Term] +id: GO:0106181 +name: obsolete translocase activity acting on inorganic anions +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic anions." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.3 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:50:54Z + +[Term] +id: GO:0106182 +name: obsolete translocase activity acting on amino acids and peptides. +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of amino acids and peptides." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.4 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:52:34Z + +[Term] +id: GO:0106183 +name: obsolete translocase activity acting on carbohydrates and their derivatives. +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.5 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:54:25Z + +[Term] +id: GO:0106184 +name: obsolete translocation activity acting on other compounds +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 ." [GOC:hjd, http://www.enzyme-database.org/] +comment: This term was made obsolete because the name and scope ( other compounds not included in EC:7.1 through EC:7.5 ) is not good ontological practice. +xref: EC:7.6 +is_obsolete: true +created_by: hjd +creation_date: 2019-04-05T15:56:19Z + +[Term] +id: GO:0106185 +name: histone H3-K37 methylation +namespace: biological_process +def: "The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone." [GOC:mah, PMID:30773398] +synonym: "histone H3 K37 methylation" EXACT [] +synonym: "histone H3K37me" EXACT [] +synonym: "histone lysine H3 K37 methylation" EXACT [] +is_a: GO:0034968 ! histone lysine methylation +created_by: hjd +creation_date: 2019-04-24T14:36:23Z + +[Term] +id: GO:0106186 +name: cytoplasmic side of plasma membrane, cell tip +namespace: cellular_component +def: "The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface." [GOC:vw, PMID:28292899] +is_a: GO:0009898 ! cytoplasmic side of plasma membrane +relationship: part_of GO:0031520 ! plasma membrane of cell tip +created_by: hjd +creation_date: 2019-05-01T17:48:02Z + +[Term] +id: GO:0106187 +name: obsolete translocase activity acting on hydrons linked to oxidoreductase reactions +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.1.1 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-07T18:04:40Z + +[Term] +id: GO:0106188 +name: obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.1.2 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-07T18:09:07Z + +[Term] +id: GO:0106189 +name: obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.1.3 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-07T18:12:33Z + +[Term] +id: GO:0106190 +name: obsolete translocase activity acting on hydrons linked to a decarboxylation reaction +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.1.4 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-07T18:17:17Z + +[Term] +id: GO:0106191 +name: obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.2.1 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T16:50:07Z + +[Term] +id: GO:0106192 +name: obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.2.2 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T16:52:54Z + +[Term] +id: GO:0106193 +name: obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.2.3 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T16:55:24Z + +[Term] +id: GO:0106194 +name: obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.2.4 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T16:58:50Z + +[Term] +id: GO:0106195 +name: obsolete translocase activty acting on inorganic anions linked to oxidoreductase reactions +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.3.1 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:13:05Z + +[Term] +id: GO:0106196 +name: obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.3.2 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:15:35Z + +[Term] +id: GO:0106197 +name: obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.3.3 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:17:37Z + +[Term] +id: GO:0106198 +name: obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.3.4 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:20:14Z + +[Term] +id: GO:0106199 +name: obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.4.1 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:23:04Z + +[Term] +id: GO:0106200 +name: obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.4.2 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:25:56Z + +[Term] +id: GO:0106201 +name: obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.4.3 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:28:18Z + +[Term] +id: GO:0106202 +name: obsolete translocase activity acting on amino acids and peptides linked to a decarboxylation reaction +namespace: molecular_function +def: "OBSOLETE. Catalysis of the translocation of amno acids and peptides linked to a decarboxylation reaction." [GOC:hjd, http://www.enzyme-database.org] +comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing. +xref: EC:7.4.4 +is_obsolete: true +created_by: hjd +creation_date: 2019-05-08T18:30:36Z + +[Term] +id: GO:0106210 +name: culmorin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris." [GOC:ach, PMID:19880637, PMID:26673640] +synonym: "culmorin anabolism" EXACT [] +synonym: "culmorin biosynthesis" EXACT [] +synonym: "culmorin formation" EXACT [] +synonym: "culmorin synthesis" EXACT [] +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0051762 ! sesquiterpene biosynthetic process +created_by: hjd +creation_date: 2019-05-13T17:30:41Z + +[Term] +id: GO:0106211 +name: inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate." [GOC:rn, PMID:29540476] +synonym: "5-diphospho-myo-inositol 1,3,4,6-tetrakisphosphate diphosphatase activity" EXACT [] +synonym: "5-diphosphoinositol 1,3,4,6-tetrakisphosphate diphosphatase activity" EXACT [] +synonym: "5-PP-InsP4 activity" EXACT [] +xref: RHEA:59500 +is_a: GO:0052840 ! inositol diphosphate tetrakisphosphate diphosphatase activity +created_by: hjd +creation_date: 2019-06-06T19:26:38Z + +[Term] +id: GO:0106212 +name: centromere detachment from spindle pole body involved in meiotic chromosome organization +namespace: biological_process +def: "The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I." [GOC:mah, PMID:27611693] +synonym: "centromere detachment from SPB involved in meiotic chromosome organization" EXACT [] +synonym: "centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle" EXACT [] +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +created_by: hjd +creation_date: 2019-06-25T18:28:39Z + +[Term] +id: GO:0106213 +name: kinetochore disassembly involved in meiotic chromosome organization +namespace: biological_process +def: "The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I." [GOC:mah, PMID:27611693] +synonym: "kinetochore disassembly from spindle pole body involved in chromosome organization involved in meiotic cell cycle" EXACT [] +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +created_by: hjd +creation_date: 2019-06-25T18:31:06Z + +[Term] +id: GO:0106214 +name: regulation of vesicle fusion with Golgi apparatus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] +is_a: GO:0031338 ! regulation of vesicle fusion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: regulates GO:0048280 ! vesicle fusion with Golgi apparatus +created_by: hjd +creation_date: 2019-06-27T15:12:22Z + +[Term] +id: GO:0106215 +name: negative regulation of vesicle fusion with Golgi apparatus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667] +is_a: GO:0031339 ! negative regulation of vesicle fusion +is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus +created_by: hjd +creation_date: 2019-06-27T15:17:17Z + +[Term] +id: GO:0106216 +name: positive regulation of vesicle fusion with Golgi apparatus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] +is_a: GO:0031340 ! positive regulation of vesicle fusion +is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus +created_by: hjd +creation_date: 2019-06-27T15:20:59Z + +[Term] +id: GO:0106217 +name: tRNA C3-cytosine methylation +namespace: biological_process +def: "The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine." [PMID:28655767] +is_a: GO:0030488 ! tRNA methylation +created_by: hjd +creation_date: 2019-07-19T19:52:40Z + +[Term] +id: GO:0106218 +name: galactosaminogalactan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN)." [PMID:173713, PMID:22102815, PMID:24257745, PMID:26492565, PMID:26932183, PMID:27048799, PMID:30667338] +synonym: "GAG biosynthetic process" RELATED [] +synonym: "galactosaminogalactan anabolism" RELATED [] +synonym: "galactosaminogalactan biosynthesis" RELATED [] +synonym: "galactosaminogalactan formation" RELATED [] +synonym: "galactosaminogalactan synthesis" RELATED [] +is_a: GO:0051278 ! fungal-type cell wall polysaccharide biosynthetic process +created_by: hjd +creation_date: 2019-08-05T14:46:56Z + +[Term] +id: GO:0106219 +name: zinc ion sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of zinc." [GOC:vw, PMID:31239353] +is_a: GO:0008270 ! zinc ion binding +is_a: GO:0140299 ! small molecule sensor activity +created_by: hjd +creation_date: 2019-08-15T16:45:43Z + +[Term] +id: GO:0106220 +name: pyocyanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group." [PMID:28715477] +synonym: "pyocyanin biosynthetic process" EXACT [] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: hjd +creation_date: 2019-08-19T17:15:48Z + +[Term] +id: GO:0106222 +name: long noncoding RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a long noncoding RNA (lncRNA)." [PMID:25578728] +synonym: "lncRNA binding" EXACT [] +is_a: GO:0003723 ! RNA binding +created_by: hjd +creation_date: 2019-08-27T14:52:58Z + +[Term] +id: GO:0106223 +name: germacrene A hydroxylase activity +namespace: molecular_function +def: "Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]." [PMID:11299372, PMID:20351109] +xref: EC:1.14.14.95 +xref: RHEA:30303 +is_a: GO:0004497 ! monooxygenase activity +created_by: hjd +creation_date: 2019-09-06T16:36:25Z + +[Term] +id: GO:0106225 +name: peptidyl-lysine 2-hydroxyisobutyrylation +namespace: biological_process +def: "The 2-hydroxyisobutyrylation of a lysine residue in a protein." [GOC:sp, PMID:29775581] +is_a: GO:0043543 ! protein acylation +created_by: hjd +creation_date: 2019-10-17T18:51:15Z + +[Term] +id: GO:0106226 +name: peptide 2-hydroxyisobutyryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide." [GOC:sp, PMID:29775581] +xref: RHEA:24180 +is_a: GO:0016410 ! N-acyltransferase activity +created_by: hjd +creation_date: 2019-10-17T18:55:24Z + +[Term] +id: GO:0106227 +name: peptidyl-lysine glutarylation +namespace: biological_process +def: "The glutarylation of a lysine residue in a protein." [GOC:sp, PMID:31542297] +is_a: GO:0043543 ! protein acylation +created_by: hjd +creation_date: 2019-10-17T18:57:19Z + +[Term] +id: GO:0106228 +name: peptide glutaryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein]." [GOC:sp, PMID:31542297] +xref: RHEA:18009 +is_a: GO:0016410 ! N-acyltransferase activity +created_by: hjd +creation_date: 2019-10-17T18:58:56Z + +[Term] +id: GO:0106229 +name: histone glutaryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone." [GOC:sp, PMID:31542297] +is_a: GO:0106228 ! peptide glutaryltransferase activity +created_by: hjd +creation_date: 2019-10-17T19:01:48Z + +[Term] +id: GO:0106230 +name: protein depropionylation +namespace: biological_process +def: "The removal of a propionyl group from a residue in a peptide or protein." [GOC:sp, PMID:30026585] +is_a: GO:0035601 ! protein deacylation +created_by: hjd +creation_date: 2019-10-17T19:10:50Z + +[Term] +id: GO:0106231 +name: protein-propionyllysine depropionylase activity +namespace: molecular_function +def: "Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide." [GOC:sp, PMID:30026585, RHEA:23500] +comment: This reaction is the removal of a propionyl group from a propionylated lysine residue of a protein or peptide. +xref: RHEA:23500 +is_a: GO:0016410 ! N-acyltransferase activity +created_by: hjd +creation_date: 2019-10-18T14:14:47Z + +[Term] +id: GO:0106232 +name: hydroxyisourate hydrolase complex +namespace: cellular_component +def: "A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin." [GOC:bhm, PMID:21795808] +synonym: "5-hydroxyisourate hydrolase complex" NARROW [] +synonym: "HIU hydrolase complex" NARROW [] +synonym: "HIUH complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: hjd +creation_date: 2019-10-31T16:34:19Z + +[Term] +id: GO:0106233 +name: glycosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis." [GOC:ach, PMID:15539076, PMID:28426655, PMID:31341002, PMID:8056787] +synonym: "glycosome biogenesis" RELATED [] +synonym: "glycosome organisation" EXACT [] +synonym: "glycosome organization and biogenesis" RELATED [] +is_a: GO:0006996 ! organelle organization +created_by: hjd +creation_date: 2019-11-01T18:29:46Z + +[Term] +id: GO:0106234 +name: outer membrane protein complex +namespace: cellular_component +def: "Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC." [GOC:am, PMID:25267629, PMID:27282389] +is_a: GO:0098796 ! membrane protein complex +created_by: hjd +creation_date: 2019-11-07T19:20:43Z + +[Term] +id: GO:0106235 +name: ceramide-1-phosphate phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate." [GOC:lb, PMID:10359651] +xref: RHEA:50888 +is_a: GO:0042577 ! lipid phosphatase activity +created_by: hjd +creation_date: 2019-11-21T20:40:39Z + +[Term] +id: GO:0106236 +name: rhamnolipid biosynthesis +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal." [GOC:vw, PMID:28715477] +synonym: "rhamnolipid production" RELATED [] +is_a: GO:0009247 ! glycolipid biosynthetic process +created_by: hjd +creation_date: 2019-12-09T18:37:49Z + +[Term] +id: GO:0106237 +name: arachidonate 12(R)-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: arachidonate + O(2)=(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate." [GOC:gap, PMID:10100631, PMID:11256953] +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +created_by: hjd +creation_date: 2019-12-18T21:03:02Z + +[Term] +id: GO:0106238 +name: peregrinol diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O." [GOC:emb, PMID:24990389, PMID:29315936, RHEA:54652] +xref: EC:4.2.1.174 +xref: RHEA:54652 +is_a: GO:0016836 ! hydro-lyase activity +created_by: hjd +creation_date: 2019-12-19T15:28:28Z + +[Term] +id: GO:0106239 +name: 9,13-epoxylabda-14-ene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate." [GOC:emb, PMID:24990389, RHEA:54512] +xref: EC:4.2.3.189 +xref: RHEA:54512 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: hjd +creation_date: 2019-12-19T16:00:49Z + +[Term] +id: GO:0106240 +name: labd-13Z-ene-9,15,16-triol synthase activity +namespace: molecular_function +def: "Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]." [GOC:eab, PMID:29315936, RHEA:62192] +xref: RHEA:62192 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: hjd +creation_date: 2019-12-19T17:43:00Z + +[Term] +id: GO:0106242 +name: kolavenyl diphosphate synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate." [GOC:eab, PMID:29315936, RHEA:54676] +xref: EC:5.5.1.29 +xref: RHEA:54676 +is_a: GO:0016872 ! intramolecular lyase activity +created_by: hjd +creation_date: 2019-12-19T18:31:00Z + +[Term] +id: GO:0106243 +name: syn-isopimara-7,15-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene." [GOC:emb, PMID:29315936, RHEA:62188] +xref: RHEA:62188 +is_a: GO:0016838 ! carbon-oxygen lyase activity, acting on phosphates +created_by: hjd +creation_date: 2019-12-19T19:04:32Z + +[Term] +id: GO:0106244 +name: eupatolide synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]." [GOC:eab, PMID:29758164, RHEA:57972] +xref: EC:1.14.14.169 +xref: RHEA:57972 +is_a: GO:0004497 ! monooxygenase activity +created_by: hjd +creation_date: 2019-12-20T14:50:15Z + +[Term] +id: GO:0106245 +name: L-serine-phosphatidylethanolamine phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine." [PMID:19014349, PMID:31869331, RHEA:27606] +xref: EC:2.7.8.29 +xref: RHEA:27606 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: hjd +creation_date: 2020-01-22T15:27:57Z + +[Term] +id: GO:0106246 +name: regulation of poly(A)-specific ribonuclease activity +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP." [GOC:mah, PMID:29932902] +is_a: GO:1901917 ! regulation of exoribonuclease activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0004535 ! poly(A)-specific ribonuclease activity +relationship: regulates GO:0004535 ! poly(A)-specific ribonuclease activity +created_by: hjd +creation_date: 2020-02-03T18:56:03Z + +[Term] +id: GO:0106247 +name: negative regulation of poly(A)-specific ribonuclease activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity." [GOC:mah, PMID:29932902] +is_a: GO:0106246 ! regulation of poly(A)-specific ribonuclease activity +is_a: GO:1901918 ! negative regulation of exoribonuclease activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0004535 ! poly(A)-specific ribonuclease activity +relationship: negatively_regulates GO:0004535 ! poly(A)-specific ribonuclease activity +created_by: hjd +creation_date: 2020-02-03T19:01:02Z + +[Term] +id: GO:0106248 +name: positive regulation of poly(A)-specific ribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity." [GOC:mah, PMID:29932902] +is_a: GO:0106246 ! regulation of poly(A)-specific ribonuclease activity +is_a: GO:1901919 ! positive regulation of exoribonuclease activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0004535 ! poly(A)-specific ribonuclease activity +relationship: positively_regulates GO:0004535 ! poly(A)-specific ribonuclease activity +created_by: hjd +creation_date: 2020-02-03T19:04:00Z + +[Term] +id: GO:0106249 +name: Nicalin-NOMO complex +namespace: cellular_component +def: "A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147." [GOC:al, GOC:bhm, PMID:20538592] +is_a: GO:0032991 ! protein-containing complex +created_by: hjd +creation_date: 2020-02-18T17:51:43Z + +[Term] +id: GO:0106250 +name: DNA-binding transcription repressor activity, RNA polymerase III-specific +namespace: molecular_function +def: "A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase III-transcribed gene to repress or decrease transcription." [GOC:vw, PMID:15590667, PMID:31833215] +is_a: GO:0001217 ! DNA-binding transcription repressor activity +created_by: hjd +creation_date: 2020-02-19T19:34:18Z + +[Term] +id: GO:0106251 +name: N4-acetylcytidine amidohydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate." [GOC:imk, PMID:31964920] +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: hjd +creation_date: 2020-02-19T20:31:17Z + +[Term] +id: GO:0106253 +name: positive regulation of DNA strand resection involved in replication fork processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing." [GOC:vw, PMID:31575705] +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:0110026 ! regulation of DNA strand resection involved in replication fork processing +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing +relationship: positively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing +created_by: hjd +creation_date: 2020-02-24T15:31:30Z + +[Term] +id: GO:0106254 +name: lipid sensor activity +namespace: molecular_function +def: "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a lipid." [GOC:vw, PMID:30075144] +is_a: GO:0140299 ! small molecule sensor activity +created_by: hjd +creation_date: 2020-03-09T17:36:09Z + +[Term] +id: GO:0106255 +name: hydroperoxy icosatetraenoate isomerase activity +namespace: molecular_function +def: "A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate." [PMID:12881489, RHEA:55560] +xref: EC:5.4.4.7 +xref: RHEA:55560 +is_a: GO:0050486 ! intramolecular transferase activity, transferring hydroxy groups +created_by: hjd +creation_date: 2020-03-20T14:00:30Z + +[Term] +id: GO:0106256 +name: hydroperoxy icosatetraenoate dehydratase activity +namespace: molecular_function +def: "A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H(2)O." [PMID:12881489, RHEA:55556] +xref: EC:4.2.1.152 +xref: RHEA:55556 +is_a: GO:0016836 ! hydro-lyase activity +created_by: hjd +creation_date: 2020-03-20T14:40:16Z + +[Term] +id: GO:0106257 +name: glycerol-3-phosphate dehydrogenase [NADP+] activity +namespace: molecular_function +def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = glycerone phosphate + NADH + H+." [RHEA:11096] +xref: RHEA:11096 +is_a: GO:0047952 ! glycerol-3-phosphate dehydrogenase [NAD(P)+] activity +created_by: hjd +creation_date: 2020-04-03T17:10:44Z + +[Term] +id: GO:0106258 +name: L-serine-phosphatidylcholine phosphatidyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline." [PMID:19014349., RHEA:45088] +xref: RHEA:45088 +is_a: GO:0016780 ! phosphotransferase activity, for other substituted phosphate groups +created_by: hjd +creation_date: 2020-04-21T17:31:56Z + +[Term] +id: GO:0106259 +name: cell-to-cell migration in host +namespace: biological_process +def: "The directional movement of a symbiont from one host cell to another." [GOC:vw, PMID:29567712] +is_a: GO:0044001 ! migration in host +created_by: hjd +creation_date: 2020-05-01T14:09:35Z + +[Term] +id: GO:0110001 +name: toxin-antitoxin complex +namespace: cellular_component +def: "A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon." [GOC:bhm, PMID:16109374, PMID:25093388] +comment: An example is YoeB (P69348) in Escherichia coli in PMID:16109374 (inferred by direct evidence). +xref: IntAct:EBI-10919614 +xref: IntAct:EBI-13949147 +xref: IntAct:EBI-13949218 +xref: IntAct:EBI-13949593 +xref: IntAct:EBI-13949715 +xref: IntAct:EBI-13949851 +is_a: GO:0017053 ! transcription repressor complex +created_by: kmv + +[Term] +id: GO:0110002 +name: regulation of tRNA methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation." [GOC:vw, PMID:23074192] +is_a: GO:2000235 ! regulation of tRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030488 ! tRNA methylation +relationship: regulates GO:0030488 ! tRNA methylation +created_by: kmv + +[Term] +id: GO:0110003 +name: regulation of tRNA C5-cytosine methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation." [GOC:vw, PMID:23074192] +is_a: GO:0110002 ! regulation of tRNA methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002946 ! tRNA C5-cytosine methylation +relationship: regulates GO:0002946 ! tRNA C5-cytosine methylation +created_by: kmv + +[Term] +id: GO:0110004 +name: positive regulation of tRNA methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA methylation." [GOC:vw, PMID:23074192] +is_a: GO:0110002 ! regulation of tRNA methylation +is_a: GO:2000237 ! positive regulation of tRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030488 ! tRNA methylation +relationship: positively_regulates GO:0030488 ! tRNA methylation +created_by: kmv + +[Term] +id: GO:0110005 +name: positive regulation of tRNA C5-cytosine methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation." [GOC:vw, PMID:23074192] +is_a: GO:0110003 ! regulation of tRNA C5-cytosine methylation +is_a: GO:0110004 ! positive regulation of tRNA methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002946 ! tRNA C5-cytosine methylation +relationship: positively_regulates GO:0002946 ! tRNA C5-cytosine methylation +created_by: kmv + +[Term] +id: GO:0110008 +name: ncRNA deadenylation +namespace: biological_process +def: "Shortening of the poly(A) tail of a nuclear-transcribed ncRNA." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:26950371] +is_a: GO:0034660 ! ncRNA metabolic process +created_by: kmv + +[Term] +id: GO:0110009 +name: formin-nucleated actin cable organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable." [GOC:mah] +is_a: GO:0061572 ! actin filament bundle organization +created_by: kmv + +[Term] +id: GO:0110010 +name: basolateral protein secretion +namespace: biological_process +def: "The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base." [GOC:ha, PMID:27404358] +is_a: GO:0009306 ! protein secretion +created_by: kmv + +[Term] +id: GO:0110011 +name: regulation of basement membrane organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358] +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071711 ! basement membrane organization +relationship: regulates GO:0071711 ! basement membrane organization +created_by: kmv + +[Term] +id: GO:0110012 +name: protein localization to P-body +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, a P-body." [GOC:mah, PMID:28031482] +synonym: "protein localisation to P-body" EXACT [GOC:mah] +synonym: "protein localization to cytoplasmic mRNA processing body" EXACT [] +synonym: "protein localization to P body" EXACT [] +is_a: GO:0033365 ! protein localization to organelle +created_by: kmv +creation_date: 2017-05-03T14:04:51Z + +[Term] +id: GO:0110013 +name: positive regulation of aggregation involved in sorocarp development +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:rjd, PMID:28257811] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0060176 ! regulation of aggregation involved in sorocarp development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031152 ! aggregation involved in sorocarp development +relationship: positively_regulates GO:0031152 ! aggregation involved in sorocarp development +created_by: kmv +creation_date: 2017-05-10T12:52:46Z + +[Term] +id: GO:0110014 +name: negative regulation of aggregation involved in sorocarp development +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug." [GOC:rjd, PMID:28257811] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0060176 ! regulation of aggregation involved in sorocarp development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031152 ! aggregation involved in sorocarp development +relationship: negatively_regulates GO:0031152 ! aggregation involved in sorocarp development +created_by: kmv +creation_date: 2017-05-10T12:53:12Z + +[Term] +id: GO:0110015 +name: positive regulation of elastin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045732 ! positive regulation of protein catabolic process +is_a: GO:0060310 ! regulation of elastin catabolic process +is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060309 ! elastin catabolic process +relationship: positively_regulates GO:0060309 ! elastin catabolic process +created_by: kmv +creation_date: 2017-05-10T14:54:12Z + +[Term] +id: GO:0110016 +name: B-WICH complex +namespace: cellular_component +def: "A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself." [GOC:bhm, PMID:16603771, PMID:21559432, PMID:23555303, PMID:26044184] +comment: An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI). +xref: IntAct:EBI-13952597 +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +relationship: part_of GO:0005730 ! nucleolus +created_by: kmv +creation_date: 2017-05-26T19:53:53Z + +[Term] +id: GO:0110017 +name: cap-independent translational initiation of linear mRNA +namespace: biological_process +def: "The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation." [GOC:kmv] +is_a: GO:0002190 ! cap-independent translational initiation +created_by: kmv +creation_date: 2017-06-08T15:13:55Z + +[Term] +id: GO:0110018 +name: cap-independent translational initiation of circular RNA +namespace: biological_process +def: "The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation." [GOC:sp, PMID:28281539, PMID:28344080, PMID:28344082] +synonym: "cap-independent translational initiation of circRNA" EXACT [] +is_a: GO:0002190 ! cap-independent translational initiation +created_by: kmv +creation_date: 2017-06-08T15:22:35Z + +[Term] +id: GO:0110019 +name: IRES-dependent translational initiation of circular RNA +namespace: biological_process +def: "The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation." [GOC:sp, PMID:28281539, PMID:28344080, PMID:28344082] +synonym: "IRES-dependent translational initiation of circRNA" EXACT [] +is_a: GO:0110018 ! cap-independent translational initiation of circular RNA +created_by: kmv +creation_date: 2017-06-08T15:36:38Z + +[Term] +id: GO:0110020 +name: regulation of actomyosin structure organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031032 ! actomyosin structure organization +relationship: regulates GO:0031032 ! actomyosin structure organization +created_by: kmv +creation_date: 2017-06-20T19:28:58Z + +[Term] +id: GO:0110021 +name: cardiac muscle myoblast proliferation +namespace: biological_process +def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] +is_a: GO:0051450 ! myoblast proliferation +created_by: kmv +creation_date: 2017-06-29T14:35:24Z + +[Term] +id: GO:0110022 +name: regulation of cardiac muscle myoblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] +is_a: GO:2000291 ! regulation of myoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0110021 ! cardiac muscle myoblast proliferation +relationship: regulates GO:0110021 ! cardiac muscle myoblast proliferation +created_by: kmv +creation_date: 2017-06-29T15:11:47Z + +[Term] +id: GO:0110023 +name: negative regulation of cardiac muscle myoblast proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] +is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation +is_a: GO:2000818 ! negative regulation of myoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation +relationship: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation +created_by: kmv +creation_date: 2017-06-29T15:18:30Z + +[Term] +id: GO:0110024 +name: positive regulation of cardiac muscle myoblast proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] +is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation +is_a: GO:2000288 ! positive regulation of myoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation +relationship: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation +created_by: kmv +creation_date: 2017-06-29T15:24:16Z + +[Term] +id: GO:0110025 +name: DNA strand resection involved in replication fork processing +namespace: biological_process +def: "The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing." [GOC:mah, PMID:28475874] +is_a: GO:0006259 ! DNA metabolic process +relationship: has_part GO:0035312 ! 5'-3' exodeoxyribonuclease activity +relationship: part_of GO:0031297 ! replication fork processing +created_by: kmv +creation_date: 2017-07-05T14:43:36Z + +[Term] +id: GO:0110026 +name: regulation of DNA strand resection involved in replication fork processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing." [GOC:mah, PMID:28475874] +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0110025 ! DNA strand resection involved in replication fork processing +relationship: regulates GO:0110025 ! DNA strand resection involved in replication fork processing +created_by: kmv +creation_date: 2017-07-05T18:21:06Z + +[Term] +id: GO:0110027 +name: negative regulation of DNA strand resection involved in replication fork processing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing." [GOC:mah, PMID:28475874] +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:0110026 ! regulation of DNA strand resection involved in replication fork processing +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing +relationship: negatively_regulates GO:0110025 ! DNA strand resection involved in replication fork processing +created_by: kmv +creation_date: 2017-07-05T18:39:49Z + +[Term] +id: GO:0110028 +name: positive regulation of mitotic spindle organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic spindle organization." [GOC:bhm, PMID:17576815] +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0060236 ! regulation of mitotic spindle organization +is_a: GO:0090068 ! positive regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007052 ! mitotic spindle organization +relationship: positively_regulates GO:0007052 ! mitotic spindle organization +created_by: kmv +creation_date: 2017-07-06T14:14:08Z + +[Term] +id: GO:0110029 +name: negative regulation of meiosis I +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [GOC:vw] +is_a: GO:0045835 ! negative regulation of meiotic nuclear division +is_a: GO:0060631 ! regulation of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007127 ! meiosis I +relationship: negatively_regulates GO:0007127 ! meiosis I +created_by: kmv +creation_date: 2017-07-12T18:47:33Z + +[Term] +id: GO:0110030 +name: regulation of G2/MI transition of meiotic cell cycle +namespace: biological_process +def: "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle." [GOC:vw] +is_a: GO:1901993 ! regulation of meiotic cell cycle phase transition +is_a: GO:1902749 ! regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +relationship: regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +created_by: kmv +creation_date: 2017-07-12T19:02:19Z + +[Term] +id: GO:0110031 +name: negative regulation of G2/MI transition of meiotic cell cycle +namespace: biological_process +def: "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle." [GOC:vw, PMID:25492408] +is_a: GO:0110030 ! regulation of G2/MI transition of meiotic cell cycle +is_a: GO:1901994 ! negative regulation of meiotic cell cycle phase transition +is_a: GO:1902750 ! negative regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +relationship: negatively_regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +created_by: kmv +creation_date: 2017-07-12T20:36:35Z + +[Term] +id: GO:0110032 +name: positive regulation of G2/MI transition of meiotic cell cycle +namespace: biological_process +def: "Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle." [GOC:vw, PMID:25492408] +is_a: GO:0110030 ! regulation of G2/MI transition of meiotic cell cycle +is_a: GO:1901995 ! positive regulation of meiotic cell cycle phase transition +is_a: GO:1902751 ! positive regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +relationship: positively_regulates GO:0008315 ! G2/MI transition of meiotic cell cycle +created_by: kmv +creation_date: 2017-07-12T20:40:54Z + +[Term] +id: GO:0110033 +name: regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)." [GOC:al, PMID:24297439] +synonym: "regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0106070 ! regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:1902659 ! regulation of glucose mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010619 ! adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +relationship: regulates GO:0010619 ! adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +created_by: kmv +creation_date: 2017-07-17T20:22:20Z + +[Term] +id: GO:0110034 +name: negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway." [GOC:al, PMID:24297439] +synonym: "negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway" EXACT [] +is_a: GO:0106072 ! negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:0110033 ! regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +is_a: GO:1902660 ! negative regulation of glucose mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010619 ! adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +relationship: negatively_regulates GO:0010619 ! adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway +created_by: kmv +creation_date: 2017-07-17T20:35:55Z + +[Term] +id: GO:0110035 +name: rDNA spacer replication fork barrier binding, bending +namespace: molecular_function +def: "The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence." [GOC:al, GOC:vw, PMID:27035982] +is_a: GO:0043110 ! rDNA spacer replication fork barrier binding +is_a: GO:0044374 ! sequence-specific DNA binding, bending +created_by: kmv +creation_date: 2017-07-17T21:09:50Z + +[Term] +id: GO:0110036 +name: C2 domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes." [GOC:sl, PMID:24882364] +is_a: GO:0019904 ! protein domain specific binding +created_by: kmv +creation_date: 2017-07-20T20:45:56Z + +[Term] +id: GO:0110037 +name: regulation of nematode male tail tip morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized." [GOC:rz, PMID:28068334] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045138 ! nematode male tail tip morphogenesis +relationship: regulates GO:0045138 ! nematode male tail tip morphogenesis +created_by: kmv +creation_date: 2017-07-24T20:21:34Z + +[Term] +id: GO:0110038 +name: negative regulation of nematode male tail tip morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis." [GOC:rz, PMID:28068334] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0110037 ! regulation of nematode male tail tip morphogenesis +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045138 ! nematode male tail tip morphogenesis +relationship: negatively_regulates GO:0045138 ! nematode male tail tip morphogenesis +created_by: kmv +creation_date: 2017-07-24T20:29:00Z + +[Term] +id: GO:0110039 +name: positive regulation of nematode male tail tip morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis." [GOC:rz, PMID:28068334] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0110037 ! regulation of nematode male tail tip morphogenesis +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045138 ! nematode male tail tip morphogenesis +relationship: positively_regulates GO:0045138 ! nematode male tail tip morphogenesis +created_by: kmv +creation_date: 2017-07-24T20:32:58Z + +[Term] +id: GO:0110040 +name: pharynx morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of the pharynx are generated and organized." [GOC:rz, PMID:20805556] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: kmv +creation_date: 2017-07-24T20:51:28Z + +[Term] +id: GO:0110041 +name: regulation of pharynx morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized." [GOC:rz, PMID:20805556] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0110040 ! pharynx morphogenesis +relationship: regulates GO:0110040 ! pharynx morphogenesis +created_by: kmv +creation_date: 2017-07-24T21:00:20Z + +[Term] +id: GO:0110042 +name: negative regulation of pharynx morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis." [GOC:rz, PMID:20805556] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0110041 ! regulation of pharynx morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0110040 ! pharynx morphogenesis +relationship: negatively_regulates GO:0110040 ! pharynx morphogenesis +created_by: kmv +creation_date: 2017-07-24T21:05:08Z + +[Term] +id: GO:0110043 +name: positive regulation of pharynx morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis." [GOC:rz, PMID:20805556] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0110041 ! regulation of pharynx morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0110040 ! pharynx morphogenesis +relationship: positively_regulates GO:0110040 ! pharynx morphogenesis +created_by: kmv +creation_date: 2017-07-24T21:09:48Z + +[Term] +id: GO:0110044 +name: regulation of cell cycle switching, mitotic to meiotic cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:al, PMID:17674143] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051445 ! regulation of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +relationship: regulates GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +created_by: kmv +creation_date: 2017-08-08T21:24:45Z + +[Term] +id: GO:0110045 +name: negative regulation of cell cycle switching, mitotic to meiotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:al, PMID:17674143] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0110044 ! regulation of cell cycle switching, mitotic to meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +relationship: negatively_regulates GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +created_by: kmv +creation_date: 2017-08-08T21:33:28Z + +[Term] +id: GO:0110046 +name: signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle +namespace: biological_process +def: "A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle." [GOC:al, PMID:17674143] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0035556 ! intracellular signal transduction +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +relationship: part_of GO:0051728 ! cell cycle switching, mitotic to meiotic cell cycle +created_by: kmv +creation_date: 2017-08-09T12:28:08Z + +[Term] +id: GO:0110050 +name: deaminated glutathione amidase activity +namespace: molecular_function +def: "Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine." [GOC:ka, PMID:28373563] +comment: N-(4-oxoglutarate)-L-cysteinylglycine = deaminated glutathione +is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides +created_by: kmv +creation_date: 2017-08-31T19:19:11Z + +[Term] +id: GO:0110051 +name: metabolite repair +namespace: biological_process +def: "A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites." [GOC:ka, PMID:23334546, PMID:28373563] +is_a: GO:0044237 ! cellular metabolic process +created_by: kmv +creation_date: 2017-09-08T15:16:01Z + +[Term] +id: GO:0110052 +name: toxic metabolite repair +namespace: biological_process +def: "A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites." [GOC:ka, GOC:vw, PMID:23334546] +is_a: GO:0110051 ! metabolite repair +is_a: GO:1990748 ! cellular detoxification +created_by: kmv +creation_date: 2017-09-08T15:19:16Z + +[Term] +id: GO:0110053 +name: regulation of actin filament organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007015 ! actin filament organization +relationship: regulates GO:0007015 ! actin filament organization +created_by: kmv +creation_date: 2017-09-20T19:52:57Z + +[Term] +id: GO:0110054 +name: regulation of actin filament annealing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments." [GOC:mah, PMID:10585915, PMID:11575927, PMID:15743909, PMID:19244341] +is_a: GO:0110053 ! regulation of actin filament organization +created_by: kmv +creation_date: 2017-09-20T20:07:58Z + +[Term] +id: GO:0110055 +name: negative regulation of actin filament annealing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments." [GOC:mah, PMID:15743909] +is_a: GO:0110054 ! regulation of actin filament annealing +created_by: kmv +creation_date: 2017-09-20T20:10:55Z + +[Term] +id: GO:0110056 +name: positive regulation of actin filament annealing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments." [GOC:mah, PMID:10585915, PMID:11575927, PMID:19244341] +is_a: GO:0110054 ! regulation of actin filament annealing +created_by: kmv +creation_date: 2017-09-20T20:13:09Z + +[Term] +id: GO:0110057 +name: regulation of blood vessel endothelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] +is_a: GO:0045601 ! regulation of endothelial cell differentiation +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060837 ! blood vessel endothelial cell differentiation +relationship: regulates GO:0060837 ! blood vessel endothelial cell differentiation +created_by: kmv +creation_date: 2017-10-23T14:32:09Z + +[Term] +id: GO:0110058 +name: positive regulation of blood vessel endothelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] +is_a: GO:0045603 ! positive regulation of endothelial cell differentiation +is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation +is_a: GO:1904018 ! positive regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation +relationship: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation +created_by: kmv +creation_date: 2017-10-23T14:38:19Z + +[Term] +id: GO:0110059 +name: negative regulation of blood vessel endothelial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] +is_a: GO:0045602 ! negative regulation of endothelial cell differentiation +is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation +is_a: GO:1901343 ! negative regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation +relationship: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation +created_by: kmv +creation_date: 2017-10-23T14:47:29Z + +[Term] +id: GO:0110061 +name: regulation of angiotensin-activated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway." [GOC:lf, PMID:28784619] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038166 ! angiotensin-activated signaling pathway +relationship: regulates GO:0038166 ! angiotensin-activated signaling pathway +created_by: kmv +creation_date: 2017-10-26T17:37:37Z + +[Term] +id: GO:0110062 +name: negative regulation of angiotensin-activated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway." [GOC:lf, PMID:28784619] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0110061 ! regulation of angiotensin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038166 ! angiotensin-activated signaling pathway +relationship: negatively_regulates GO:0038166 ! angiotensin-activated signaling pathway +created_by: kmv +creation_date: 2017-10-26T17:42:17Z + +[Term] +id: GO:0110063 +name: positive regulation of angiotensin-activated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway." [GOC:lf, PMID:28784619] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0110061 ! regulation of angiotensin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038166 ! angiotensin-activated signaling pathway +relationship: positively_regulates GO:0038166 ! angiotensin-activated signaling pathway +created_by: kmv +creation_date: 2017-10-26T17:47:37Z + +[Term] +id: GO:0110064 +name: lncRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length." [GOC:al, PMID:24493644] +synonym: "lncRNA breakdown" EXACT [] +synonym: "lncRNA catabolism" EXACT [] +synonym: "lncRNA degradation" EXACT [] +is_a: GO:0034661 ! ncRNA catabolic process +created_by: kmv +creation_date: 2017-11-06T13:49:49Z + +[Term] +id: GO:0110065 +name: regulation of interphase mitotic telomere clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase." [GOC:vw, PMID:25778919] +synonym: "regulation of mitotic telomere clustering during interphase" EXACT [] +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120110 ! interphase mitotic telomere clustering +relationship: regulates GO:0120110 ! interphase mitotic telomere clustering +created_by: kmv +creation_date: 2017-11-17T22:03:40Z + +[Term] +id: GO:0110066 +name: negative regulation of interphase mitotic telomere clustering +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase." [GOC:vw, PMID:25778919] +synonym: "negative regulation of mitotic telomere clustering during interphase" EXACT [] +synonym: "telomere dispersion during interphase" EXACT [GOC:vw, PMID:25778919] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0110065 ! regulation of interphase mitotic telomere clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120110 ! interphase mitotic telomere clustering +relationship: negatively_regulates GO:0120110 ! interphase mitotic telomere clustering +created_by: kmv +creation_date: 2017-11-17T22:11:59Z + +[Term] +id: GO:0110067 +name: ammonium transmembrane transporter complex +namespace: cellular_component +def: "High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other." [GOC:bhm, PMID:17026539, PMID:23463773] +synonym: "AMT1 complex" NARROW [GOC:bhm] +xref: IntAct:EBI-16426073 +is_a: GO:1902495 ! transmembrane transporter complex +created_by: kmv +creation_date: 2017-11-20T15:21:10Z + +[Term] +id: GO:0110068 +name: glucosylglycerate phosphorylase activity +namespace: molecular_function +def: "Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate." [GOC:imk, PMID:28754708] +is_a: GO:0004645 ! 1,4-alpha-oligoglucan phosphorylase activity +created_by: kmv +creation_date: 2017-11-21T21:50:10Z + +[Term] +id: GO:0110069 +name: syncytial embryo cellularization +namespace: biological_process +def: "The separation of a syncytial embryo into individual cells." [GOC:ha, PMID:27226317] +is_a: GO:0007349 ! cellularization +is_a: GO:0051301 ! cell division +relationship: part_of GO:0009790 ! embryo development +created_by: kmv +creation_date: 2017-11-22T19:59:19Z + +[Term] +id: GO:0110070 +name: cellularization cleavage furrow +namespace: cellular_component +def: "A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells." [GOC:ha, PMID:27226317] +is_a: GO:0032154 ! cleavage furrow +created_by: kmv +creation_date: 2017-11-22T20:10:14Z + +[Term] +id: GO:0110071 +name: cellularization cleavage furrow invagination front +namespace: cellular_component +def: "The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane." [GOC:ha, PMID:27226317] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0110070 ! cellularization cleavage furrow +created_by: kmv +creation_date: 2017-11-22T20:13:21Z + +[Term] +id: GO:0110072 +name: apical constriction involved in ventral furrow formation +namespace: biological_process +def: "The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation." [GOC:ha, PMID:28495958] +is_a: GO:0003384 ! apical constriction involved in gastrulation +intersection_of: GO:0003383 ! apical constriction +intersection_of: part_of GO:0007370 ! ventral furrow formation +relationship: part_of GO:0007370 ! ventral furrow formation +created_by: kmv +creation_date: 2017-12-06T17:04:49Z + +[Term] +id: GO:0110073 +name: regulation of apical constriction involved in ventral furrow formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation." [GOC:ha, PMID:28495958] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0110072 ! apical constriction involved in ventral furrow formation +relationship: regulates GO:0110072 ! apical constriction involved in ventral furrow formation +created_by: kmv +creation_date: 2017-12-06T17:30:29Z + +[Term] +id: GO:0110074 +name: positive regulation of apical constriction involved in ventral furrow formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation." [GOC:ha, PMID:28495958] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0110073 ! regulation of apical constriction involved in ventral furrow formation +is_a: GO:1903116 ! positive regulation of actin filament-based movement +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0110072 ! apical constriction involved in ventral furrow formation +relationship: positively_regulates GO:0110072 ! apical constriction involved in ventral furrow formation +created_by: kmv +creation_date: 2017-12-06T17:39:00Z + +[Term] +id: GO:0110075 +name: regulation of ferroptosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferroptosis." [GOC:sp, PMID:24439385, PMID:25402683, PMID:29290465] +is_a: GO:0043067 ! regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097707 ! ferroptosis +relationship: regulates GO:0097707 ! ferroptosis +created_by: kmv +creation_date: 2018-01-11T17:51:48Z + +[Term] +id: GO:0110076 +name: negative regulation of ferroptosis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis." [GOC:sp, PMID:24439385, PMID:25402683, PMID:29290465] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0110075 ! regulation of ferroptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097707 ! ferroptosis +relationship: negatively_regulates GO:0097707 ! ferroptosis +created_by: kmv +creation_date: 2018-01-11T18:00:05Z + +[Term] +id: GO:0110077 +name: vesicle-mediated intercellular transport +namespace: biological_process +def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916] +is_a: GO:0010496 ! intercellular transport +is_a: GO:0016192 ! vesicle-mediated transport +created_by: kmv +creation_date: 2018-01-29T14:46:52Z + +[Term] +id: GO:0110078 +name: TTT complex +namespace: cellular_component +def: "A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209)." [GOC:lnp, PMID:20810650, PMID:22505622, PMID:28827813] +synonym: "Tel2-Tti1-Tti2" EXACT [GOC:lnp, PMID:28827813] +synonym: "TELO2-TTI1-TTI2" EXACT [GOC:lnp] +synonym: "Triple T complex" EXACT [GOC:lnp, PMID:20810650] +xref: IntAct:EBI-16631004 +is_a: GO:0032991 ! protein-containing complex +created_by: kmv +creation_date: 2018-01-29T21:39:52Z + +[Term] +id: GO:0110079 +name: regulation of placenta blood vessel development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] +is_a: GO:1901342 ! regulation of vasculature development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0060674 ! placenta blood vessel development +relationship: regulates GO:0060674 ! placenta blood vessel development +created_by: kmv +creation_date: 2018-02-01T14:49:12Z + +[Term] +id: GO:0110080 +name: positive regulation of placenta blood vessel development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] +is_a: GO:0110079 ! regulation of placenta blood vessel development +is_a: GO:1904018 ! positive regulation of vasculature development +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0060674 ! placenta blood vessel development +relationship: positively_regulates GO:0060674 ! placenta blood vessel development +created_by: kmv +creation_date: 2018-02-01T14:55:30Z + +[Term] +id: GO:0110081 +name: negative regulation of placenta blood vessel development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] +is_a: GO:0110079 ! regulation of placenta blood vessel development +is_a: GO:1901343 ! negative regulation of vasculature development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0060674 ! placenta blood vessel development +relationship: negatively_regulates GO:0060674 ! placenta blood vessel development +created_by: kmv +creation_date: 2018-02-01T15:01:11Z + +[Term] +id: GO:0110082 +name: regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly." [GOC:vw, PMID:29343550] +is_a: GO:1901900 ! regulation of protein localization to cell division site +is_a: GO:1903499 ! regulation of mitotic actomyosin contractile ring assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +relationship: regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +created_by: kmv +creation_date: 2018-02-01T19:25:06Z + +[Term] +id: GO:0110083 +name: positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly." [GOC:vw, PMID:29343550] +is_a: GO:0110082 ! regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +is_a: GO:1903501 ! positive regulation of mitotic actomyosin contractile ring assembly +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +relationship: positively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +created_by: kmv +creation_date: 2018-02-01T19:30:03Z + +[Term] +id: GO:0110084 +name: negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly." [GOC:vw, PMID:29343550] +is_a: GO:0110082 ! regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +is_a: GO:1903500 ! negative regulation of mitotic actomyosin contractile ring assembly +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +relationship: negatively_regulates GO:1903476 ! protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +created_by: kmv +creation_date: 2018-02-01T19:33:51Z + +[Term] +id: GO:0110085 +name: mitotic actomyosin contractile ring +namespace: cellular_component +def: "A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis." [GOC:vw, PMID:27505246] +is_a: GO:0005826 ! actomyosin contractile ring +created_by: kmv +creation_date: 2018-02-12T17:04:02Z + +[Term] +id: GO:0110086 +name: meiotic actomyosin contractile ring +namespace: cellular_component +def: "A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis." [GOC:vw, PMID:22526418] +is_a: GO:0005826 ! actomyosin contractile ring +created_by: kmv +creation_date: 2018-02-12T17:26:17Z + +[Term] +id: GO:0110087 +name: suppression by virus of host protease activator activity +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity." [PMID:23303392] +is_a: GO:0039507 ! suppression by virus of host molecular function +created_by: kmv +creation_date: 2018-02-12T20:17:29Z + +[Term] +id: GO:0110088 +name: hippocampal neuron apoptotic process +namespace: biological_process +def: "Any apoptotic process that occurs in a hippocampal neuron." [GOC:sl, PMID:18940801] +is_a: GO:0051402 ! neuron apoptotic process +created_by: kmv +creation_date: 2018-02-13T21:06:23Z + +[Term] +id: GO:0110089 +name: regulation of hippocampal neuron apoptotic process +namespace: biological_process +def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons." [GOC:sl, PMID:18940801] +is_a: GO:0043523 ! regulation of neuron apoptotic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0110088 ! hippocampal neuron apoptotic process +relationship: regulates GO:0110088 ! hippocampal neuron apoptotic process +created_by: kmv +creation_date: 2018-02-13T21:18:29Z + +[Term] +id: GO:0110090 +name: positive regulation of hippocampal neuron apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons." [GOC:sl, PMID:18940801] +is_a: GO:0043525 ! positive regulation of neuron apoptotic process +is_a: GO:0110089 ! regulation of hippocampal neuron apoptotic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0110088 ! hippocampal neuron apoptotic process +relationship: positively_regulates GO:0110088 ! hippocampal neuron apoptotic process +created_by: kmv +creation_date: 2018-02-13T21:22:18Z + +[Term] +id: GO:0110091 +name: negative regulation of hippocampal neuron apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons." [GOC:sl, PMID:18940801] +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +is_a: GO:0110089 ! regulation of hippocampal neuron apoptotic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0110088 ! hippocampal neuron apoptotic process +relationship: negatively_regulates GO:0110088 ! hippocampal neuron apoptotic process +created_by: kmv +creation_date: 2018-02-13T21:25:01Z + +[Term] +id: GO:0110092 +name: nucleus leading edge +namespace: cellular_component +def: "The area of a motile nucleus closest to the direction of movement." [GOC:al, GOC:mah, GOC:vw, PMID:15030757, PMID:24335254] +synonym: "horsetail nucleus leading edge" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005634 ! nucleus +created_by: kmv +creation_date: 2018-02-14T22:39:58Z + +[Term] +id: GO:0110093 +name: nucleus lagging edge +namespace: cellular_component +def: "The area of a motile nucleus furthest from the direction of movement." [GOC:kmv, PMID:24335254] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005634 ! nucleus +created_by: kmv +creation_date: 2018-02-14T22:56:12Z + +[Term] +id: GO:0110094 +name: polyphosphate-mediated signaling +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal." [GOC:rjd, PMID:27519410, PMID:28584190] +synonym: "polyphosphate signaling" EXACT [GOC:rjd] +is_a: GO:0007267 ! cell-cell signaling +created_by: kmv +creation_date: 2018-02-15T16:42:30Z + +[Term] +id: GO:0110095 +name: cellular detoxification of aldehyde +namespace: biological_process +def: "Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw, PMID:25656103] +is_a: GO:1990748 ! cellular detoxification +relationship: part_of GO:0110096 ! cellular response to aldehyde +created_by: kmv +creation_date: 2018-02-16T21:19:20Z + +[Term] +id: GO:0110096 +name: cellular response to aldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus." [GOC:vw, PMID:25656103] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: kmv +creation_date: 2018-02-16T21:29:18Z + +[Term] +id: GO:0110097 +name: regulation of calcium import into the mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion." [GOC:sl, PMID:24085037] +is_a: GO:0090279 ! regulation of calcium ion import +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0036444 ! calcium import into the mitochondrion +relationship: regulates GO:0036444 ! calcium import into the mitochondrion +created_by: kmv +creation_date: 2018-02-28T00:33:51Z + +[Term] +id: GO:0110098 +name: positive regulation of calcium import into the mitochondrion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion." [GOC:sl, PMID:24085037] +is_a: GO:0090280 ! positive regulation of calcium ion import +is_a: GO:0110097 ! regulation of calcium import into the mitochondrion +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0036444 ! calcium import into the mitochondrion +relationship: positively_regulates GO:0036444 ! calcium import into the mitochondrion +created_by: kmv +creation_date: 2018-02-28T00:39:13Z + +[Term] +id: GO:0110099 +name: negative regulation of calcium import into the mitochondrion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion." [GOC:sl, PMID:24085037] +is_a: GO:0090281 ! negative regulation of calcium ion import +is_a: GO:0110097 ! regulation of calcium import into the mitochondrion +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0036444 ! calcium import into the mitochondrion +relationship: negatively_regulates GO:0036444 ! calcium import into the mitochondrion +created_by: kmv +creation_date: 2018-02-28T00:42:06Z + +[Term] +id: GO:0110100 +name: spindle pole body separation +namespace: biological_process +def: "The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble." [GOC:vw] +comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0022402 ! cell cycle process +relationship: part_of GO:0051300 ! spindle pole body organization +created_by: kmv +creation_date: 2018-03-06T15:09:28Z + +[Term] +id: GO:0110101 +name: L-valine transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of L-valine into the vacuole across the vacuolar membrane." [GOC:al, PMID:20944394] +is_a: GO:0034491 ! neutral amino acid transmembrane import into vacuole +is_a: GO:1903785 ! L-valine transmembrane transport +created_by: kmv +creation_date: 2018-03-14T19:56:06Z + +[Term] +id: GO:0110102 +name: chloroplast ribulose bisphosphate carboxylase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a chloroplast ribulose bisphosphate carboxylase complex." [GOC:tb, PMID:29396988] +synonym: "chloroplast rubisco assembly" EXACT [GOC:tb] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: kmv +creation_date: 2018-03-15T17:24:14Z + +[Term] +id: GO:0110103 +name: RNA polymerase II termination complex +namespace: cellular_component +def: "A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end." [GOC:lnp, PMID:23200120, PMID:25722373] +comment: In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1. +synonym: "TXT complex" EXACT [PMID:23084833] +xref: IntAct:EBI-16426399 +is_a: GO:1905354 ! exoribonuclease complex +created_by: kmv +creation_date: 2018-03-16T18:55:17Z + +[Term] +id: GO:0110104 +name: mRNA alternative polyadenylation +namespace: biological_process +def: "The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals)." [GOC:ans, PMID:28453393, PMID:29276085] +is_a: GO:1900363 ! regulation of mRNA polyadenylation +created_by: kmv +creation_date: 2018-03-27T19:26:56Z + +[Term] +id: GO:0110105 +name: mRNA cleavage and polyadenylation specificity factor complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex." [GOC:mah, PMID:27401558] +is_a: GO:0034622 ! cellular protein-containing complex assembly +relationship: part_of GO:0031123 ! RNA 3'-end processing +created_by: kmv +creation_date: 2018-04-13T19:05:17Z + +[Term] +id: GO:0110107 +name: regulation of imaginal disc-derived wing vein specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification." [GOC:ha, PMID:11861482] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0007474 ! imaginal disc-derived wing vein specification +relationship: regulates GO:0007474 ! imaginal disc-derived wing vein specification +created_by: kmv +creation_date: 2018-07-05T13:44:08Z + +[Term] +id: GO:0110108 +name: positive regulation of imaginal disc-derived wing vein specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification." [GOC:ha, PMID:11861482] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0110107 ! regulation of imaginal disc-derived wing vein specification +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0007474 ! imaginal disc-derived wing vein specification +relationship: positively_regulates GO:0007474 ! imaginal disc-derived wing vein specification +created_by: kmv +creation_date: 2018-07-05T13:52:31Z + +[Term] +id: GO:0110109 +name: negative regulation of imaginal disc-derived wing vein specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification." [GOC:ha, PMID:11861482] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0110107 ! regulation of imaginal disc-derived wing vein specification +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0007474 ! imaginal disc-derived wing vein specification +relationship: negatively_regulates GO:0007474 ! imaginal disc-derived wing vein specification +created_by: kmv +creation_date: 2018-07-05T13:55:37Z + +[Term] +id: GO:0110110 +name: positive regulation of animal organ morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0009887 ! animal organ morphogenesis +relationship: positively_regulates GO:0009887 ! animal organ morphogenesis +created_by: kmv +creation_date: 2018-07-05T14:10:14Z + +[Term] +id: GO:0110111 +name: negative regulation of animal organ morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0009887 ! animal organ morphogenesis +relationship: negatively_regulates GO:0009887 ! animal organ morphogenesis +created_by: kmv +creation_date: 2018-07-05T14:25:21Z + +[Term] +id: GO:0110112 +name: regulation of lipid transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0032409 ! regulation of transporter activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0005319 ! lipid transporter activity +relationship: regulates GO:0005319 ! lipid transporter activity +created_by: kmv +creation_date: 2018-07-06T18:53:55Z + +[Term] +id: GO:0110113 +name: positive regulation of lipid transporter activity +namespace: biological_process +def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0032411 ! positive regulation of transporter activity +is_a: GO:0110112 ! regulation of lipid transporter activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0005319 ! lipid transporter activity +relationship: positively_regulates GO:0005319 ! lipid transporter activity +created_by: kmv +creation_date: 2018-07-06T19:14:13Z + +[Term] +id: GO:0110114 +name: negative regulation of lipid transporter activity +namespace: biological_process +def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0032410 ! negative regulation of transporter activity +is_a: GO:0110112 ! regulation of lipid transporter activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0005319 ! lipid transporter activity +relationship: negatively_regulates GO:0005319 ! lipid transporter activity +created_by: kmv +creation_date: 2018-07-06T19:21:44Z + +[Term] +id: GO:0110115 +name: Cdr2 medial cortical node complex +namespace: cellular_component +def: "A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase." [GOC:vw, PMID:29514920] +synonym: "interphase cortical node" EXACT [GOC:vw] +synonym: "interphase node" EXACT [GOC:vw] +is_a: GO:1902911 ! protein kinase complex +relationship: part_of GO:0071341 ! medial cortical node +created_by: kmv +creation_date: 2018-07-10T14:02:26Z + +[Term] +id: GO:0110116 +name: regulation of compound eye photoreceptor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] +is_a: GO:0046532 ! regulation of photoreceptor cell differentiation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0001751 ! compound eye photoreceptor cell differentiation +relationship: regulates GO:0001751 ! compound eye photoreceptor cell differentiation +created_by: kmv +creation_date: 2018-07-16T18:08:49Z + +[Term] +id: GO:0110117 +name: positive regulation of compound eye photoreceptor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] +is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation +relationship: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation +created_by: kmv +creation_date: 2018-07-16T18:13:28Z + +[Term] +id: GO:0110118 +name: negative regulation of compound eye photoreceptor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] +is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation +relationship: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation +created_by: kmv +creation_date: 2018-07-16T18:15:52Z + +[Term] +id: GO:0110119 +name: positive regulation of very-low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:25510864] +is_a: GO:0010915 ! regulation of very-low-density lipoprotein particle clearance +is_a: GO:0010986 ! positive regulation of lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034447 ! very-low-density lipoprotein particle clearance +relationship: positively_regulates GO:0034447 ! very-low-density lipoprotein particle clearance +created_by: kmv +creation_date: 2018-07-27T14:13:47Z + +[Term] +id: GO:0110120 +name: gamma-tubulin complex localization to nuclear side of mitotic spindle pole body +namespace: biological_process +def: "Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body." [GOC:vw, PMID:19942852] +is_a: GO:1990735 ! gamma-tubulin complex localization to mitotic spindle pole body +created_by: kmv +creation_date: 2018-07-27T15:42:46Z + +[Term] +id: GO:0110121 +name: gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body +namespace: biological_process +def: "Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body." [GOC:vw, PMID:19001497] +is_a: GO:1990735 ! gamma-tubulin complex localization to mitotic spindle pole body +created_by: kmv +creation_date: 2018-07-27T15:49:05Z + +[Term] +id: GO:0110122 +name: myotube cell migration +namespace: biological_process +def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742] +is_a: GO:0014812 ! muscle cell migration +created_by: kmv +creation_date: 2018-08-22T20:58:09Z + +[Term] +id: GO:0110123 +name: regulation of myotube cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0110122 ! myotube cell migration +relationship: regulates GO:0110122 ! myotube cell migration +created_by: kmv +creation_date: 2018-08-22T21:06:53Z + +[Term] +id: GO:0110124 +name: positive regulation of myotube cell migration +namespace: biological_process +def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0110123 ! regulation of myotube cell migration +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0110122 ! myotube cell migration +relationship: positively_regulates GO:0110122 ! myotube cell migration +created_by: kmv +creation_date: 2018-08-22T21:09:38Z + +[Term] +id: GO:0110125 +name: negative regulation of myotube cell migration +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0110123 ! regulation of myotube cell migration +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0110122 ! myotube cell migration +relationship: negatively_regulates GO:0110122 ! myotube cell migration +created_by: kmv +creation_date: 2018-08-22T21:12:47Z + +[Term] +id: GO:0110126 +name: phloem loading +namespace: biological_process +def: "The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink." [GOC:lr, PMID:19025382] +is_a: GO:0010233 ! phloem transport +created_by: kmv +creation_date: 2018-09-07T21:24:54Z + +[Term] +id: GO:0110127 +name: phloem unloading +namespace: biological_process +def: "The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues." [GOC:lr, PMID:19025382] +is_a: GO:0010233 ! phloem transport +created_by: kmv +creation_date: 2018-09-07T21:33:07Z + +[Term] +id: GO:0110128 +name: phloem sucrose unloading +namespace: biological_process +def: "The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues." [GOC:lr, PMID:30018170] +is_a: GO:0015770 ! sucrose transport +is_a: GO:0110127 ! phloem unloading +created_by: kmv +creation_date: 2018-09-07T21:38:52Z + +[Term] +id: GO:0110129 +name: SHREC2 complex +namespace: cellular_component +def: "A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2." [GOC:mah, PMID:19111658] +is_a: GO:0000118 ! histone deacetylase complex +is_a: GO:0017053 ! transcription repressor complex +relationship: has_part GO:0070824 ! SHREC complex +created_by: kmv +creation_date: 2018-09-25T21:25:41Z + +[Term] +id: GO:0110130 +name: ribitol-5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate." [GOC:rn, PMID:30240188] +xref: RHEA:47648 +is_a: GO:0016791 ! phosphatase activity +created_by: kmv +creation_date: 2018-10-08T19:47:57Z + +[Term] +id: GO:0110131 +name: Aim21-Tda2 complex +namespace: cellular_component +def: "A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables." [GOC:rn, PMID:28706108, PMID:29467252] +synonym: "Aim21/Tda2 complex" EXACT [] +xref: ComplexPortal:CPX-3541 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030479 ! actin cortical patch +created_by: kmv +creation_date: 2018-10-09T21:08:36Z + +[Term] +id: GO:0110132 +name: regulation of CRISPR-cas system +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a CRISPR-cas system." [PMID:30190307, PMID:30190308] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099048 ! CRISPR-cas system +relationship: regulates GO:0099048 ! CRISPR-cas system +created_by: kmv +creation_date: 2018-11-14T17:13:16Z + +[Term] +id: GO:0110133 +name: negative regulation of CRISPR-cas system +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system." [PMID:30190307, PMID:30190308] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0110132 ! regulation of CRISPR-cas system +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0099048 ! CRISPR-cas system +relationship: negatively_regulates GO:0099048 ! CRISPR-cas system +created_by: kmv +creation_date: 2018-11-14T17:23:07Z + +[Term] +id: GO:0110134 +name: meiotic drive +namespace: biological_process +def: "A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis." [GOC:mah, PMID:26920473, PMID:29322557, PMID:29499907] +is_a: GO:0022414 ! reproductive process +created_by: kmv +creation_date: 2019-01-02T17:37:09Z + +[Term] +id: GO:0110135 +name: Norrin signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state." [GOC:BHF, GOC:rl, PMID:15035989, PMID:17955262] +is_a: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling +created_by: kmv +creation_date: 2019-01-18T19:07:18Z + +[Term] +id: GO:0110136 +name: protein-RNA complex remodeling +namespace: biological_process +def: "The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex." [GOC:rn, PMID:19737519, PMID:20542003, PMID:24240281] +is_a: GO:0034367 ! protein-containing complex remodeling +is_a: GO:0071826 ! ribonucleoprotein complex subunit organization +created_by: kmv +creation_date: 2019-01-22T19:23:17Z + +[Term] +id: GO:0110137 +name: regulation of imaginal disc-derived leg joint morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized." [GOC:ha, PMID:25329825] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +relationship: regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +created_by: kmv +creation_date: 2019-02-12T15:31:25Z + +[Term] +id: GO:0110138 +name: positive regulation of imaginal disc-derived leg joint morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis." [GOC:ha, PMID:25329825] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:0110137 ! regulation of imaginal disc-derived leg joint morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +relationship: positively_regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +created_by: kmv +creation_date: 2019-02-12T15:37:05Z + +[Term] +id: GO:0110139 +name: negative regulation of imaginal disc-derived leg joint morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis." [GOC:ha, PMID:25329825] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:0110137 ! regulation of imaginal disc-derived leg joint morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +relationship: negatively_regulates GO:0007480 ! imaginal disc-derived leg morphogenesis +created_by: kmv +creation_date: 2019-02-12T15:40:09Z + +[Term] +id: GO:0110140 +name: flagellum attachment zone organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species." [GOC:ach, PMID:26776656] +synonym: "FAZ organization" EXACT [] +synonym: "flagellum attachment zone organisation" EXACT [] +is_a: GO:0034330 ! cell junction organization +created_by: kmv +creation_date: 2019-03-04T19:55:50Z + +[Term] +id: GO:0110141 +name: L-glutamate import into mitochondrion +namespace: biological_process +def: "The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix." [GOC:vw, PMID:30297026] +is_a: GO:0015813 ! L-glutamate transmembrane transport +is_a: GO:0051938 ! L-glutamate import +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: kmv +creation_date: 2019-04-24T19:13:46Z + +[Term] +id: GO:0110142 +name: ubiquinone biosynthesis complex +namespace: cellular_component +def: "The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K." [GOC:imk, PMID:27060254, PMID:28927698, PMID:30686758] +synonym: "CoQ metabolon" EXACT [PMID:28927698] +synonym: "Ubi complex" EXACT [PMID:30686758] +is_a: GO:0032991 ! protein-containing complex +created_by: kmv +creation_date: 2019-04-25T15:48:21Z + +[Term] +id: GO:0110143 +name: magnetosome +namespace: cellular_component +def: "A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles." [GOC:aa, PMID:27620945] +is_a: GO:0043226 ! organelle +created_by: kmv +creation_date: 2019-05-30T17:31:21Z + +[Term] +id: GO:0110144 +name: obsolete magnetosome part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria." [GOC:aa, PMID:27620945] +is_obsolete: true +consider: GO:0110143 +created_by: kmv +creation_date: 2019-05-30T17:36:02Z + +[Term] +id: GO:0110145 +name: magnetosome lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a magnetosome." [GOC:aa, PMID:27620945] +is_a: GO:0043233 ! organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0110143 ! magnetosome +relationship: part_of GO:0110143 ! magnetosome +created_by: kmv +creation_date: 2019-05-30T17:42:14Z + +[Term] +id: GO:0110146 +name: magnetosome membrane +namespace: cellular_component +def: "The lipid bilayer surrounding a magnetosome." [GOC:aa, PMID:27620945] +is_a: GO:0031090 ! organelle membrane +relationship: part_of GO:0110143 ! magnetosome +created_by: kmv +creation_date: 2019-05-30T17:51:09Z + +[Term] +id: GO:0110147 +name: protein maturation by nickel ion transfer +namespace: biological_process +def: "A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation." [GOC:al, PMID:24115911] +is_a: GO:0051604 ! protein maturation +created_by: kmv +creation_date: 2019-05-31T14:41:20Z + +[Term] +id: GO:0110148 +name: biomineralization +namespace: biological_process +def: "The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products." [GOC:aa, PMID:24395694, PMID:28229486] +synonym: "biomineral formation" NARROW [] +synonym: "biomineralisation" EXACT [] +synonym: "mineralisation" EXACT [] +synonym: "mineralization" EXACT [] +xref: Wikipedia:Biomineralization +is_a: GO:0008150 ! biological_process +created_by: kmv +creation_date: 2019-06-10T17:55:28Z + +[Term] +id: GO:0110149 +name: regulation of biomineralization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms." [PMID:22992051] +synonym: "regulation of biomineral formation" NARROW [] +synonym: "regulation of biomineralisation" EXACT [] +synonym: "regulation of mineralisation" EXACT [] +synonym: "regulation of mineralization" EXACT [] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0110148 ! biomineralization +relationship: regulates GO:0110148 ! biomineralization +created_by: kmv +creation_date: 2019-06-10T18:06:59Z + +[Term] +id: GO:0110150 +name: negative regulation of biomineralization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms." [PMID:22992051] +synonym: "negative regulation of biomineral formation" NARROW [] +synonym: "negative regulation of biomineralisation" EXACT [] +synonym: "negative regulation of mineralisation" EXACT [] +synonym: "negative regulation of mineralization" EXACT [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0110149 ! regulation of biomineralization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0110148 ! biomineralization +relationship: negatively_regulates GO:0110148 ! biomineralization +created_by: kmv +creation_date: 2019-06-10T18:12:24Z + +[Term] +id: GO:0110151 +name: positive regulation of biomineralization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms." [PMID:22992051] +synonym: "positive regulation of biomineral formation" NARROW [] +synonym: "positive regulation of biomineralisation" EXACT [] +synonym: "positive regulation of mineralisation" EXACT [] +synonym: "positive regulation of mineralization" EXACT [] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0110149 ! regulation of biomineralization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0110148 ! biomineralization +relationship: positively_regulates GO:0110148 ! biomineralization +created_by: kmv +creation_date: 2019-06-10T18:18:01Z + +[Term] +id: GO:0110152 +name: RNA NAD-cap (NAD-forming) hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+)." [GOC:sp, PMID:28283058] +comment: This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides +created_by: kmv +creation_date: 2019-07-08T15:55:11Z + +[Term] +id: GO:0110153 +name: RNA NAD-cap (NMN-forming) hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)." [GOC:sp, PMID:25533955, PMID:31101919] +comment: This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. +is_a: GO:0016818 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides +created_by: kmv +creation_date: 2019-07-08T17:15:59Z + +[Term] +id: GO:0110154 +name: RNA decapping +namespace: biological_process +def: "Cleavage of the 5'-cap of an RNA." [GOC:sp, PMID:25533955, PMID:31101919] +is_a: GO:0016070 ! RNA metabolic process +created_by: kmv +creation_date: 2019-07-08T17:23:59Z + +[Term] +id: GO:0110155 +name: NAD-cap decapping +namespace: biological_process +def: "Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes." [GOC:sp, PMID:25533955, PMID:28283058, PMID:31101919] +is_a: GO:0110154 ! RNA decapping +created_by: kmv +creation_date: 2019-07-08T17:27:56Z + +[Term] +id: GO:0110156 +name: methylguanosine-cap decapping +namespace: biological_process +def: "Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA." [PMID:23287066] +is_a: GO:0110154 ! RNA decapping +created_by: kmv +creation_date: 2019-07-08T17:31:07Z + +[Term] +id: GO:0110157 +name: reelin complex +namespace: cellular_component +def: "An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain." [GOC:bhm, PMID:21844191, PMID:28887403] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005615 ! extracellular space +created_by: kmv +creation_date: 2019-07-15T15:10:58Z + +[Term] +id: GO:0110158 +name: calpain complex +namespace: cellular_component +def: "A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate." [GOC:bhm, PMID:10639123] +synonym: "M-calpain" NARROW [] +synonym: "mu-calpain" NARROW [] +is_a: GO:0008303 ! caspase complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: kmv +creation_date: 2019-07-15T18:30:51Z + +[Term] +id: GO:0110159 +name: regulation of mitotic spindle formation (spindle phase one) +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic spindle formation (spindle phase one)." [GOC:vw] +is_a: GO:0032888 ! regulation of mitotic spindle elongation +is_a: GO:1901673 ! regulation of mitotic spindle assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +relationship: regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +created_by: kmv +creation_date: 2019-08-12T15:10:26Z + +[Term] +id: GO:0110160 +name: negative regulation of mitotic spindle formation (spindle phase one) +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle formation (spindle phase one)." [GOC:vw] +is_a: GO:0110159 ! regulation of mitotic spindle formation (spindle phase one) +is_a: GO:1902845 ! negative regulation of mitotic spindle elongation +is_a: GO:1905831 ! negative regulation of spindle assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +relationship: negatively_regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +created_by: kmv +creation_date: 2019-08-12T15:18:32Z + +[Term] +id: GO:0110161 +name: positive regulation of mitotic spindle formation (spindle phase one) +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic spindle formation (spindle phase one)." [GOC:vw] +is_a: GO:0110159 ! regulation of mitotic spindle formation (spindle phase one) +is_a: GO:1902846 ! positive regulation of mitotic spindle elongation +is_a: GO:1905832 ! positive regulation of spindle assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +relationship: positively_regulates GO:0061804 ! mitotic spindle formation (spindle phase one) +created_by: kmv +creation_date: 2019-08-12T15:21:08Z + +[Term] +id: GO:0110162 +name: regulation of mitotic spindle elongation (spindle phase three) +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic spindle elongation (spindle phase three)." [GOC:vw, PMID:27697865] +is_a: GO:0032888 ! regulation of mitotic spindle elongation +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +relationship: regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +created_by: kmv +creation_date: 2019-08-12T15:26:01Z + +[Term] +id: GO:0110163 +name: negative regulation of mitotic spindle elongation (spindle phase three) +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation (spindle phase three)." [GOC:vw, PMID:27697865] +is_a: GO:0110162 ! regulation of mitotic spindle elongation (spindle phase three) +is_a: GO:1902845 ! negative regulation of mitotic spindle elongation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +relationship: negatively_regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +created_by: kmv +creation_date: 2019-08-12T15:29:43Z + +[Term] +id: GO:0110164 +name: positive regulation of mitotic spindle elongation (spindle phase three) +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation (spindle phase three)." [GOC:vw, PMID:27697865] +is_a: GO:0110162 ! regulation of mitotic spindle elongation (spindle phase three) +is_a: GO:1902846 ! positive regulation of mitotic spindle elongation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +relationship: positively_regulates GO:0061805 ! mitotic spindle elongation (spindle phase three) +created_by: kmv +creation_date: 2019-08-12T15:32:20Z + +[Term] +id: GO:0110165 +name: cellular anatomical entity +namespace: cellular_component +def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv] +is_a: GO:0005575 ! cellular_component +created_by: kmv +creation_date: 2019-08-12T18:01:37Z + +[Term] +id: GO:0110166 +name: DNA synthesis involved in mitochondrial DNA replication +namespace: biological_process +def: "Any DNA biosynthetic process that is involved in mitochondrial DNA replication." [PMID:28408491, PMID:29931097] +synonym: "DNA biosynthetic process involved in mitochondrial DNA replication" EXACT [] +is_a: GO:0032042 ! mitochondrial DNA metabolic process +is_a: GO:0090592 ! DNA synthesis involved in DNA replication +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:0006264 ! mitochondrial DNA replication +relationship: part_of GO:0006264 ! mitochondrial DNA replication +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17716 xsd:anyURI +created_by: kmv +creation_date: 2020-03-18T13:30:39Z + +[Term] +id: GO:0120001 +name: apical plasma membrane urothelial plaque +namespace: cellular_component +def: "A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array." [GOC:krc, PMID:21468280, PMID:21887288] +synonym: "asymmetric unit membrane" EXACT [] +synonym: "AUM" RELATED [] +is_a: GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0016324 ! apical plasma membrane +created_by: krc +creation_date: 2017-02-23T21:10:27Z + +[Term] +id: GO:0120002 +name: fusiform vesicle +namespace: cellular_component +def: "A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder." [GOC:krc, PMID:21468280, PMID:21887288] +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: krc +creation_date: 2017-02-23T21:12:27Z + +[Term] +id: GO:0120003 +name: hinge region between urothelial plaques of apical plasma membrane +namespace: cellular_component +def: "A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane." [GOC:krc, PMID:21468280, PMID:21887288] +is_a: GO:0098590 ! plasma membrane region +relationship: part_of GO:0016324 ! apical plasma membrane +created_by: krc +creation_date: 2017-02-23T22:13:27Z + +[Term] +id: GO:0120006 +name: regulation of glutamatergic neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation." [PMID:24030726] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905962 ! glutamatergic neuron differentiation +relationship: regulates GO:1905962 ! glutamatergic neuron differentiation +created_by: krc +creation_date: 2017-03-01T16:10:27Z + +[Term] +id: GO:0120007 +name: negative regulation of glutamatergic neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation." [PMID:24030726] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:0120006 ! regulation of glutamatergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905962 ! glutamatergic neuron differentiation +relationship: negatively_regulates GO:1905962 ! glutamatergic neuron differentiation +created_by: krc +creation_date: 2017-03-01T16:25:50Z + +[Term] +id: GO:0120008 +name: positive regulation of glutamatergic neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation." [PMID:24030726] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:0120006 ! regulation of glutamatergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905962 ! glutamatergic neuron differentiation +relationship: positively_regulates GO:1905962 ! glutamatergic neuron differentiation +created_by: krc +creation_date: 2017-03-01T16:35:45Z + +[Term] +id: GO:0120009 +name: intermembrane lipid transfer +namespace: biological_process +def: "The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +is_a: GO:0006869 ! lipid transport +is_a: GO:0061024 ! membrane organization +created_by: krc +creation_date: 2017-03-16T20:30:42Z + +[Term] +id: GO:0120010 +name: intermembrane phospholipid transfer +namespace: biological_process +def: "The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +is_a: GO:0015914 ! phospholipid transport +is_a: GO:0120009 ! intermembrane lipid transfer +created_by: krc +creation_date: 2017-03-16T20:56:03Z + +[Term] +id: GO:0120011 +name: intermembrane sterol transfer +namespace: biological_process +def: "The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +is_a: GO:0015918 ! sterol transport +is_a: GO:0120009 ! intermembrane lipid transfer +created_by: krc +creation_date: 2017-03-16T22:15:40Z + +[Term] +id: GO:0120012 +name: intermembrane sphingolipid transfer +namespace: biological_process +def: "The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0120009 ! intermembrane lipid transfer +created_by: krc +creation_date: 2017-03-16T22:20:45Z + +[Term] +id: GO:0120013 +name: lipid transfer activity +namespace: molecular_function +def: "Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane lipid transfer activity" EXACT [] +synonym: "lipid carrier activity" EXACT [] +is_a: GO:0005319 ! lipid transporter activity +relationship: part_of GO:0120009 ! intermembrane lipid transfer +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17648 xsd:anyURI +created_by: krc +creation_date: 2017-03-17T03:17:29Z + +[Term] +id: GO:0120014 +name: phospholipid transfer activity +namespace: molecular_function +def: "Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane phospholipid transfer activity" NARROW [] +synonym: "phospholipid carrier activity" EXACT [] +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0120013 ! lipid transfer activity +relationship: has_part GO:0005543 ! phospholipid binding +created_by: krc +creation_date: 2017-03-17T03:34:17Z + +[Term] +id: GO:0120015 +name: sterol transfer activity +namespace: molecular_function +def: "Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane sterol transfer activity" NARROW [] +synonym: "sterol carrier activity" EXACT [] +is_a: GO:0015248 ! sterol transporter activity +is_a: GO:0120013 ! lipid transfer activity +relationship: has_part GO:0032934 ! sterol binding +created_by: krc +creation_date: 2017-03-17T03:46:28Z + +[Term] +id: GO:0120016 +name: sphingolipid transfer activity +namespace: molecular_function +def: "Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane sphingolipid transfer activity" NARROW [] +synonym: "sphingolipid carrier activity" NARROW [] +is_a: GO:0046624 ! sphingolipid transporter activity +is_a: GO:0120013 ! lipid transfer activity +relationship: has_part GO:0046625 ! sphingolipid binding +created_by: krc +creation_date: 2017-03-17T03:52:30Z + +[Term] +id: GO:0120017 +name: ceramide transfer activity +namespace: molecular_function +alt_id: GO:0035620 +def: "Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "ceramide carrier activity" EXACT [] +synonym: "ceramide transporter activity" BROAD [] +synonym: "intermembrane ceramide transfer activity" NARROW [] +is_a: GO:0120016 ! sphingolipid transfer activity +relationship: has_part GO:0097001 ! ceramide binding +created_by: krc +creation_date: 2010-12-08T12:32:50Z + +[Term] +id: GO:0120019 +name: phosphatidylcholine transfer activity +namespace: molecular_function +def: "Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane phosphatidylcholine transfer activity" NARROW [] +synonym: "phosphatidylcholine carrier activity" EXACT [] +is_a: GO:0008525 ! phosphatidylcholine transporter activity +is_a: GO:0120014 ! phospholipid transfer activity +relationship: has_part GO:0031210 ! phosphatidylcholine binding +created_by: krc +creation_date: 2017-03-17T04:22:47Z + +[Term] +id: GO:0120020 +name: cholesterol transfer activity +namespace: molecular_function +alt_id: GO:0017127 +def: "Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "cholesterol carrier activity" EXACT [] +synonym: "cholesterol transporter activity" BROAD [] +synonym: "intermembrane cholesterol transfer activity" NARROW [] +is_a: GO:0120015 ! sterol transfer activity +relationship: has_part GO:0015485 ! cholesterol binding +created_by: krc +creation_date: 2017-03-17T04:46:12Z + +[Term] +id: GO:0120021 +name: oxysterol transfer activity +namespace: molecular_function +def: "Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198] +synonym: "intermembrane oxysterol transfer activity" NARROW [] +synonym: "oxysterol carrier activity" EXACT [] +is_a: GO:0120015 ! sterol transfer activity +relationship: has_part GO:0008142 ! oxysterol binding +created_by: krc +creation_date: 2017-03-17T04:50:30Z + +[Term] +id: GO:0120022 +name: glucagon binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glucagon, a polypeptide hormone involved in glucose response. It is produced by pancreatic alpha cells and raises the concentration of glucose in the blood." [GOC:cvs] +is_a: GO:0017046 ! peptide hormone binding +created_by: krc +creation_date: 2017-03-17T14:46:29Z + +[Term] +id: GO:0120023 +name: somatostatin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin." [GOC:cvs, PMID:20472043] +is_a: GO:0017046 ! peptide hormone binding +created_by: krc +creation_date: 2017-03-17T14:54:21Z + +[Term] +id: GO:0120024 +name: glucagon-like peptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glucagon-like peptide, a antihyperglycemic hormone. Glucagon-like peptide is derived from the glucagon gene produced by pancreatic alpha cells." [GOC:cvs] +is_a: GO:0017046 ! peptide hormone binding +created_by: krc +creation_date: 2017-03-17T14:57:26Z + +[Term] +id: GO:0120025 +name: plasma membrane bounded cell projection +namespace: cellular_component +def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] +is_a: GO:0042995 ! cell projection +intersection_of: GO:0042995 ! cell projection +intersection_of: has_part GO:0098590 ! plasma membrane region +relationship: has_part GO:0098590 ! plasma membrane region +created_by: krc +creation_date: 2017-03-21T17:26:07Z + +[Term] +id: GO:0120026 +name: host cell uropod +namespace: cellular_component +def: "A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively." [PMID:24965475] +synonym: "host cell uropodium" EXACT [] +is_a: GO:0044157 ! host cell projection +created_by: krc +creation_date: 2017-03-22T21:33:31Z + +[Term] +id: GO:0120027 +name: regulation of osmosensory signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osmosensory signaling pathway." [GOC:vw] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0106049 ! regulation of cellular response to osmotic stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007231 ! osmosensory signaling pathway +relationship: regulates GO:0007231 ! osmosensory signaling pathway +created_by: krc +creation_date: 2017-03-31T14:45:01Z + +[Term] +id: GO:0120028 +name: negative regulation of osmosensory signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway." [GOC:vw] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0120027 ! regulation of osmosensory signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007231 ! osmosensory signaling pathway +relationship: negatively_regulates GO:0007231 ! osmosensory signaling pathway +created_by: krc +creation_date: 2017-03-31T15:00:28Z + +[Term] +id: GO:0120029 +name: proton export across plasma membrane +namespace: biological_process +def: "The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region." [GOC:mah, PMID:9762918] +synonym: "hydrogen ion export across plasma membrane" EXACT [] +synonym: "hydrogen ion export from cell" BROAD [] +synonym: "proton export across plasma membrane" EXACT [] +synonym: "proton export from cell" BROAD [] +is_a: GO:0140115 ! export across plasma membrane +is_a: GO:1902600 ! proton transmembrane transport +created_by: krc +creation_date: 2017-03-31T17:39:03Z + +[Term] +id: GO:0120030 +name: positive regulation of cilium beat frequency involved in ciliary motility +namespace: biological_process +def: "Any process that activates or increases the frequency of cilium beating involved in ciliary motility." [PMID:28035044] +is_a: GO:0060296 ! regulation of cilium beat frequency involved in ciliary motility +created_by: krc +creation_date: 2017-04-19T14:32:16Z + +[Term] +id: GO:0120031 +name: plasma membrane bounded cell projection assembly +namespace: biological_process +def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] +synonym: "eupodium" NARROW [GOC:krc, GOC:rjd, PMID:10328951, PMID:9096956] +is_a: GO:0030031 ! cell projection assembly +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +created_by: krc +creation_date: 2017-04-24T23:56:08Z + +[Term] +id: GO:0120032 +name: regulation of plasma membrane bounded cell projection assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc] +is_a: GO:0060491 ! regulation of cell projection assembly +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: regulates GO:0120031 ! plasma membrane bounded cell projection assembly +created_by: krc +creation_date: 2017-04-26T04:27:04Z + +[Term] +id: GO:0120033 +name: negative regulation of plasma membrane bounded cell projection assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly +created_by: krc +creation_date: 2017-04-26T04:34:31Z + +[Term] +id: GO:0120034 +name: positive regulation of plasma membrane bounded cell projection assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly +relationship: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly +created_by: krc +creation_date: 2017-04-26T04:34:45Z + +[Term] +id: GO:0120035 +name: regulation of plasma membrane bounded cell projection organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc] +is_a: GO:0031344 ! regulation of cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120036 ! plasma membrane bounded cell projection organization +relationship: regulates GO:0120036 ! plasma membrane bounded cell projection organization +created_by: krc +creation_date: 2017-04-26T16:02:06Z + +[Term] +id: GO:0120036 +name: plasma membrane bounded cell projection organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] +is_a: GO:0030030 ! cell projection organization +created_by: krc +creation_date: 2017-04-26T16:07:02Z + +[Term] +id: GO:0120038 +name: obsolete plasma membrane bounded cell projection part +namespace: cellular_component +def: "OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] +is_obsolete: true +consider: GO:0120025 +created_by: krc +creation_date: 2017-04-28T17:20:43Z + +[Term] +id: GO:0120039 +name: plasma membrane bounded cell projection morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc] +is_a: GO:0048858 ! cell projection morphogenesis +created_by: krc +creation_date: 2017-04-28T23:39:37Z + +[Term] +id: GO:0120040 +name: regulation of macrophage proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0070663 ! regulation of leukocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061517 ! macrophage proliferation +relationship: regulates GO:0061517 ! macrophage proliferation +created_by: krc +creation_date: 2017-05-10T20:38:19Z + +[Term] +id: GO:0120041 +name: positive regulation of macrophage proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0070665 ! positive regulation of leukocyte proliferation +is_a: GO:0120040 ! regulation of macrophage proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061517 ! macrophage proliferation +relationship: positively_regulates GO:0061517 ! macrophage proliferation +created_by: krc +creation_date: 2017-05-10T20:45:01Z + +[Term] +id: GO:0120042 +name: negative regulation of macrophage proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0070664 ! negative regulation of leukocyte proliferation +is_a: GO:0120040 ! regulation of macrophage proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061517 ! macrophage proliferation +relationship: negatively_regulates GO:0061517 ! macrophage proliferation +created_by: krc +creation_date: 2017-05-10T20:51:40Z + +[Term] +id: GO:0120043 +name: stereocilium shaft +namespace: cellular_component +def: "The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle." [GOC:krc, PMID:20170899] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032420 ! stereocilium +created_by: krc +creation_date: 2017-05-15T20:38:32Z + +[Term] +id: GO:0120044 +name: stereocilium base +namespace: cellular_component +def: "The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium." [GOC:krc, PMID:20170899] +synonym: "stereocilium taper" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032420 ! stereocilium +created_by: krc +creation_date: 2017-05-15T20:45:06Z + +[Term] +id: GO:0120045 +name: stereocilium maintenance +namespace: biological_process +def: "The organization process that preserves a stereocilium in a stable functional or structural state." [GOC:krc, PMID:27693694] +is_a: GO:0043954 ! cellular component maintenance +is_a: GO:0060122 ! inner ear receptor cell stereocilium organization +created_by: krc +creation_date: 2017-05-15T20:55:13Z + +[Term] +id: GO:0120046 +name: regulation of protein localization to medial cortical node +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node." [PMID:19474789] +is_a: GO:0106011 ! regulation of protein localization to medial cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902577 ! protein localization to medial cortical node +relationship: regulates GO:1902577 ! protein localization to medial cortical node +created_by: krc +creation_date: 2017-06-02T17:29:23Z + +[Term] +id: GO:0120047 +name: positive regulation of protein localization to medial cortical node +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node." [PMID:19474789] +is_a: GO:0106012 ! positive regulation of protein localization to medial cortex +is_a: GO:0120046 ! regulation of protein localization to medial cortical node +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902577 ! protein localization to medial cortical node +relationship: positively_regulates GO:1902577 ! protein localization to medial cortical node +created_by: krc +creation_date: 2017-06-02T17:30:38Z + +[Term] +id: GO:0120048 +name: U6 snRNA (adenine-(43)-N(6))-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA." [PMID:28525753] +is_a: GO:0008173 ! RNA methyltransferase activity +created_by: krc +creation_date: 2017-06-02T20:37:40Z + +[Term] +id: GO:0120049 +name: snRNA (adenine-N6)-methylation +namespace: biological_process +def: "The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule." [PMID:28525753] +is_a: GO:0040031 ! snRNA modification +created_by: krc +creation_date: 2017-06-02T20:56:51Z + +[Term] +id: GO:0120053 +name: ribitol beta-1,4-xylosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R." [PMID:27733679] +is_a: GO:0035252 ! UDP-xylosyltransferase activity +created_by: krc +creation_date: 2017-06-13T19:35:01Z + +[Term] +id: GO:0120054 +name: intestinal motility +namespace: biological_process +def: "Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth)." [GOC:sl, PMID:15890336] +is_a: GO:0022600 ! digestive system process +created_by: krc +creation_date: 2017-06-13T20:42:24Z + +[Term] +id: GO:0120055 +name: small intestinal transit +namespace: biological_process +def: "Migration of ingested material along the length of the small intestine." [GOC:sl, PMID:15890336] +synonym: "small bowel transit" EXACT [] +synonym: "small intestine transit" EXACT [] +is_a: GO:0120054 ! intestinal motility +created_by: krc +creation_date: 2017-06-13T20:46:41Z + +[Term] +id: GO:0120056 +name: large intestinal transit +namespace: biological_process +def: "Migration of ingested material along the length of the large intestine." [GOC:sl, PMID:28157109] +synonym: "colon transit" EXACT [] +synonym: "colonic transit" EXACT [] +synonym: "large bowel transit" EXACT [] +synonym: "large intestine transit" EXACT [] +is_a: GO:0120054 ! intestinal motility +created_by: krc +creation_date: 2017-06-13T20:52:01Z + +[Term] +id: GO:0120057 +name: regulation of small intestinal transit +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine." [GOC:sl, PMID:15890336] +synonym: "regulation of small bowel transit" EXACT [] +synonym: "regulation of small intestine transit" EXACT [] +is_a: GO:0044058 ! regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120055 ! small intestinal transit +relationship: regulates GO:0120055 ! small intestinal transit +created_by: krc +creation_date: 2017-06-13T20:56:46Z + +[Term] +id: GO:0120058 +name: positive regulation of small intestinal transit +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine." [GOC:sl, PMID:15890336] +synonym: "positive regulation of small bowel transit" EXACT [] +synonym: "positive regulation of small intestine transit" EXACT [] +is_a: GO:0060456 ! positive regulation of digestive system process +is_a: GO:0120057 ! regulation of small intestinal transit +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0120055 ! small intestinal transit +relationship: positively_regulates GO:0120055 ! small intestinal transit +created_by: krc +creation_date: 2017-06-13T20:58:23Z + +[Term] +id: GO:0120059 +name: negative regulation of small intestinal transit +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine." [GOC:sl, PMID:15890336] +synonym: "negative regulation of small bowel transit" EXACT [] +synonym: "negative regulation of small intestine transit" EXACT [] +is_a: GO:0060457 ! negative regulation of digestive system process +is_a: GO:0120057 ! regulation of small intestinal transit +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120055 ! small intestinal transit +relationship: negatively_regulates GO:0120055 ! small intestinal transit +created_by: krc +creation_date: 2017-06-13T20:58:23Z + +[Term] +id: GO:0120060 +name: regulation of gastric emptying +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum." [GOC:sl, PMID:15890336] +synonym: "regulation of small bowel emptying" EXACT [] +synonym: "regulation of small intestine emptying" EXACT [] +is_a: GO:1905333 ! regulation of gastric motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035483 ! gastric emptying +relationship: regulates GO:0035483 ! gastric emptying +created_by: krc +creation_date: 2017-06-13T21:47:16Z + +[Term] +id: GO:0120061 +name: negative regulation of gastric emptying +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum." [GOC:sl, PMID:15890336] +is_a: GO:0060457 ! negative regulation of digestive system process +is_a: GO:0120060 ! regulation of gastric emptying +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035483 ! gastric emptying +relationship: negatively_regulates GO:0035483 ! gastric emptying +created_by: krc +creation_date: 2017-06-13T21:54:49Z + +[Term] +id: GO:0120062 +name: positive regulation of gastric emptying +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum." [GOC:sl, PMID:15890336] +is_a: GO:0060456 ! positive regulation of digestive system process +is_a: GO:0120060 ! regulation of gastric emptying +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035483 ! gastric emptying +relationship: positively_regulates GO:0035483 ! gastric emptying +created_by: krc +creation_date: 2017-06-13T21:55:08Z + +[Term] +id: GO:0120063 +name: stomach smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach." [GOC:sl, PMID:15890336] +is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T22:20:16Z + +[Term] +id: GO:0120064 +name: stomach pylorus smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach." [GOC:sl, PMID:15890336] +is_a: GO:0014828 ! distal stomach smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T22:32:04Z + +[Term] +id: GO:0120065 +name: pyloric antrum smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach." [GOC:sl, PMID:15890336] +synonym: "antrum smooth muscle contraction" EXACT [] +is_a: GO:0120064 ! stomach pylorus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T22:36:20Z + +[Term] +id: GO:0120066 +name: pyloric canal smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter." [GOC:sl, PMID:15890336] +is_a: GO:0120064 ! stomach pylorus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T22:37:51Z + +[Term] +id: GO:0120067 +name: pyloric sphincter smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum." [GOC:sl, PMID:15890336] +is_a: GO:0120064 ! stomach pylorus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T22:38:26Z + +[Term] +id: GO:0120068 +name: regulation of stomach fundus smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014825 ! stomach fundus smooth muscle contraction +relationship: regulates GO:0014825 ! stomach fundus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:22:52Z + +[Term] +id: GO:0120069 +name: positive regulation of stomach fundus smooth muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:0120068 ! regulation of stomach fundus smooth muscle contraction +is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014825 ! stomach fundus smooth muscle contraction +relationship: positively_regulates GO:0014825 ! stomach fundus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:27:25Z + +[Term] +id: GO:0120070 +name: negative regulation of stomach fundus smooth muscle contraction +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:0120068 ! regulation of stomach fundus smooth muscle contraction +is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014825 ! stomach fundus smooth muscle contraction +relationship: negatively_regulates GO:0014825 ! stomach fundus smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:27:40Z + +[Term] +id: GO:0120071 +name: regulation of pyloric antrum smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0120065 ! pyloric antrum smooth muscle contraction +relationship: regulates GO:0120065 ! pyloric antrum smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:32:39Z + +[Term] +id: GO:0120072 +name: positive regulation of pyloric antrum smooth muscle contraction +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:0120071 ! regulation of pyloric antrum smooth muscle contraction +is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0120065 ! pyloric antrum smooth muscle contraction +relationship: positively_regulates GO:0120065 ! pyloric antrum smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:32:56Z + +[Term] +id: GO:0120073 +name: negative regulation of pyloric antrum smooth muscle contraction +namespace: biological_process +def: "Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction." [GOC:sl, PMID:15890336] +is_a: GO:0120071 ! regulation of pyloric antrum smooth muscle contraction +is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0120065 ! pyloric antrum smooth muscle contraction +relationship: negatively_regulates GO:0120065 ! pyloric antrum smooth muscle contraction +created_by: krc +creation_date: 2017-06-13T23:33:11Z + +[Term] +id: GO:0120074 +name: regulation of endocardial cushion cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061443 ! endocardial cushion cell differentiation +relationship: regulates GO:0061443 ! endocardial cushion cell differentiation +created_by: krc +creation_date: 2017-06-26T23:32:00Z + +[Term] +id: GO:0120075 +name: positive regulation of endocardial cushion cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0120074 ! regulation of endocardial cushion cell differentiation +is_a: GO:1905209 ! positive regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061443 ! endocardial cushion cell differentiation +relationship: positively_regulates GO:0061443 ! endocardial cushion cell differentiation +created_by: krc +creation_date: 2017-06-26T23:36:59Z + +[Term] +id: GO:0120076 +name: negative regulation of endocardial cushion cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0120074 ! regulation of endocardial cushion cell differentiation +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061443 ! endocardial cushion cell differentiation +relationship: negatively_regulates GO:0061443 ! endocardial cushion cell differentiation +created_by: krc +creation_date: 2017-06-26T23:37:23Z + +[Term] +id: GO:0120077 +name: angiogenic sprout fusion +namespace: biological_process +def: "Def: The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis." [GOC:cvs, PMID:28264837] +synonym: "angiogenic sprout fusion" EXACT [] +synonym: "blood vessel anastomosis" EXACT [] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: has_part GO:0120078 ! cell adhesion involved in sprouting angiogenesis +relationship: part_of GO:0002040 ! sprouting angiogenesis +created_by: krc +creation_date: 2017-06-27T21:16:55Z + +[Term] +id: GO:0120078 +name: cell adhesion involved in sprouting angiogenesis +namespace: biological_process +def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network." [GOC:cvs, PMID:28264837] +synonym: "cell adhesion involved in blood vessel anastomosis" EXACT [] +synonym: "cell adhesion involved in vascular anastomosis" RELATED [] +is_a: GO:0007155 ! cell adhesion +intersection_of: GO:0007155 ! cell adhesion +intersection_of: part_of GO:0120077 ! angiogenic sprout fusion +relationship: part_of GO:0120077 ! angiogenic sprout fusion +created_by: krc +creation_date: 2017-06-27T21:29:47Z + +[Term] +id: GO:0120079 +name: regulation of microfilament motor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microfilament motor activity." [GOC:mah, PMID:20705471] +synonym: "regulation of actin filament motor activity" EXACT [] +synonym: "regulation of actin-filament motor activity" EXACT [] +synonym: "regulation of muscle motor activity" NARROW [] +synonym: "regulation of myosin ATPase activity" RELATED [] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000146 ! microfilament motor activity +relationship: regulates GO:0000146 ! microfilament motor activity +created_by: krc +creation_date: 2017-07-05T20:53:49Z + +[Term] +id: GO:0120080 +name: negative regulation of microfilament motor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity." [GOC:mah, PMID:20705471] +synonym: "negative regulation of actin filament motor activity" EXACT [] +synonym: "negative regulation of actin-filament motor activity" EXACT [] +synonym: "negative regulation of muscle motor activity" NARROW [] +synonym: "negative regulation of myosin ATPase activity" RELATED [] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0120079 ! regulation of microfilament motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000146 ! microfilament motor activity +relationship: negatively_regulates GO:0000146 ! microfilament motor activity +created_by: krc +creation_date: 2017-07-05T21:36:47Z + +[Term] +id: GO:0120081 +name: positive regulation of microfilament motor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microfilament motor activity." [GOC:mah, PMID:20705471] +synonym: "positive regulation of actin filament motor activity" EXACT [] +synonym: "positive regulation of actin-filament motor activity" EXACT [] +synonym: "positive regulation of muscle motor activity" NARROW [] +synonym: "positive regulation of myosin ATPase activity" BROAD [] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0120079 ! regulation of microfilament motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000146 ! microfilament motor activity +relationship: positively_regulates GO:0000146 ! microfilament motor activity +created_by: krc +creation_date: 2017-07-05T21:48:56Z + +[Term] +id: GO:0120082 +name: smooth endoplasmic reticulum cisterna +namespace: cellular_component +def: "A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity." [GOC:sl, PMID:12112448] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005790 ! smooth endoplasmic reticulum +relationship: part_of GO:0071781 ! endoplasmic reticulum cisternal network +created_by: krc +creation_date: 2017-07-05T23:32:11Z + +[Term] +id: GO:0120083 +name: rough endoplasmic reticulum cisterna +namespace: cellular_component +def: "A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity." [GOC:sl, PMID:12112448] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0071781 ! endoplasmic reticulum cisternal network +created_by: krc +creation_date: 2017-07-05T23:38:49Z + +[Term] +id: GO:0120084 +name: endothelial tip cell filopodium assembly +namespace: biological_process +def: "The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout." [GOC:cvs, PMID:28264837] +is_a: GO:0046847 ! filopodium assembly +created_by: krc +creation_date: 2017-07-07T18:05:10Z + +[Term] +id: GO:0120085 +name: transposon integration involved in RNA-mediated transposition +namespace: biological_process +def: "Any transposon integration that contributes to a process of RNA-mediated transposition." [GOC:mah, PMID:26358720] +synonym: "retrotransposon integration" EXACT [] +is_a: GO:0070893 ! transposon integration +intersection_of: GO:0070893 ! transposon integration +intersection_of: part_of GO:0032197 ! transposition, RNA-mediated +relationship: part_of GO:0032197 ! transposition, RNA-mediated +created_by: krc +creation_date: 2017-07-07T22:17:32Z + +[Term] +id: GO:0120086 +name: (3S)-(+)-asterisca-2(9),6-diene synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene." [PMID:27862766] +synonym: "asterisca-2(9),6-diene synthase activity" BROAD [] +is_a: GO:0010334 ! sesquiterpene synthase activity +created_by: krc +creation_date: 2017-08-02T14:55:38Z + +[Term] +id: GO:0120091 +name: jasmonic acid hydrolase +namespace: molecular_function +def: "Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid." [PMID:28559313, PMID:28760569] +synonym: "2-oxoglutarate dioxygenase" BROAD [] +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +created_by: krc +creation_date: 2017-08-18T23:25:52Z + +[Term] +id: GO:0120092 +name: crotonyl-CoA hydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine." [PMID:28803779] +xref: RHEA:45584 +is_a: GO:0016836 ! hydro-lyase activity +created_by: krc +creation_date: 2017-08-22T20:13:55Z + +[Term] +id: GO:0120093 +name: regulation of peptidyl-lysine crotonylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein." [PMID:28803779] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0140066 ! peptidyl-lysine crotonylation +relationship: regulates GO:0140066 ! peptidyl-lysine crotonylation +created_by: krc +creation_date: 2017-08-22T20:25:51Z + +[Term] +id: GO:0120094 +name: negative regulation of peptidyl-lysine crotonylation +namespace: biological_process +def: "Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein." [PMID:28803779] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0120093 ! regulation of peptidyl-lysine crotonylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0140066 ! peptidyl-lysine crotonylation +relationship: negatively_regulates GO:0140066 ! peptidyl-lysine crotonylation +created_by: krc +creation_date: 2017-08-22T20:36:36Z + +[Term] +id: GO:0120095 +name: vacuole-isolation membrane contact site +namespace: cellular_component +def: "An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome." [PMID:23549786] +synonym: "vacuole-IM contact site" EXACT [] +synonym: "vacuole-phagophore contact site" EXACT [] +synonym: "VICS" RELATED [] +is_a: GO:0044232 ! organelle membrane contact site +created_by: krc +creation_date: 2017-09-18T20:01:35Z + +[Term] +id: GO:0120097 +name: glycosylphosphatidylinositol-mannosyltransferase II complex +namespace: cellular_component +def: "A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p." [GOC:bhm, PMID:17615295] +synonym: "GPI-MT-I complex" RELATED [] +xref: IntAct:EBI-16398134 +is_a: GO:0031501 ! mannosyltransferase complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +created_by: krc +creation_date: 2017-09-18T20:51:56Z + +[Term] +id: GO:0120098 +name: procentriole +namespace: cellular_component +def: "A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells." [GOC:bhm, GOC:krc, PMID:18620859, PMID:21289083, PMID:25047614] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: krc +creation_date: 2017-09-28T21:22:56Z + +[Term] +id: GO:0120099 +name: procentriole replication complex +namespace: cellular_component +def: "A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates." [GOC:bhm, PMID:17576815, PMID:18207742, PMID:21059844, PMID:22020124, PMID:24997597] +xref: IntAct:EBI-15188467 +xref: IntAct:EBI-15189349 +xref: IntAct:EBI-15316456 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: krc +creation_date: 2017-09-28T21:41:34Z + +[Term] +id: GO:0120100 +name: bacterial-type flagellum motor +namespace: cellular_component +def: "A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation." [DOI:10.1002/9780470015902.a0000744.pub4, GOC:cilia, PMID:10572114, PMID:12624192, PMID:24697492, PMID:25251856] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009425 ! bacterial-type flagellum basal body +created_by: krc +creation_date: 2017-10-03T15:44:35Z + +[Term] +id: GO:0120101 +name: bacterial-type flagellum stator complex +namespace: cellular_component +def: "A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species." [GOC:cilia, PMID:10572114, PMID:12624192, PMID:24697492, PMID:25251856] +synonym: "bacterial-type flagellum motor force generator complex" EXACT [PMID:24697492] +synonym: "bacterial-type flagellum torque generator complex" EXACT [DOI:10.1002/9780470015902.a0000744.pub4] +is_a: GO:0005887 ! integral component of plasma membrane +relationship: part_of GO:0120100 ! bacterial-type flagellum motor +created_by: krc +creation_date: 2017-10-03T16:06:16Z + +[Term] +id: GO:0120102 +name: bacterial-type flagellum secretion apparatus +namespace: cellular_component +def: "A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament." [DOI:10.1002/9780470015902.a0000744.pub4, GOC:cilia, PMID:10572114, PMID:12624192, PMID:24697492, PMID:25251856] +synonym: "bacterial-type flagellum export apparatus" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0009425 ! bacterial-type flagellum basal body +created_by: krc +creation_date: 2017-10-03T16:13:24Z + +[Term] +id: GO:0120103 +name: centriolar subdistal appendage +namespace: cellular_component +def: "A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68." [GOC:cilia, PMID:23213374, PMID:27818179, PMID:28422092] +synonym: "subdistal appendage of basal body" EXACT [GOC:krc] +synonym: "subdistal appendage of centriole" EXACT [GOC:krc] +synonym: "subdistal appendage of mother centriole" EXACT [GOC:krc] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005929 ! cilium +created_by: krc +creation_date: 2017-10-10T15:31:40Z + +[Term] +id: GO:0120104 +name: actomyosin contractile ring, proximal layer +namespace: cellular_component +def: "The region of the actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located." [GOC:krc, GOC:vw, PMID:28914606] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005826 ! actomyosin contractile ring +created_by: krc +creation_date: 2017-10-11T22:49:58Z + +[Term] +id: GO:0120105 +name: actomyosin contractile ring, intermediate layer +namespace: cellular_component +def: "The region of the actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer." [GOC:krc, GOC:vw, PMID:28914606] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005826 ! actomyosin contractile ring +created_by: krc +creation_date: 2017-10-11T22:54:40Z + +[Term] +id: GO:0120106 +name: actomyosin contractile ring, distal actin filament layer +namespace: cellular_component +def: "The region of the actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to." [GOC:krc, GOC:vw, PMID:28914606] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005826 ! actomyosin contractile ring +created_by: krc +creation_date: 2017-10-11T22:56:44Z + +[Term] +id: GO:0120107 +name: bacterial-type flagellum rotor complex +namespace: cellular_component +def: "The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation." [GOC:cilia, PMID:10572114, PMID:12624192, PMID:25251856] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0120100 ! bacterial-type flagellum motor +created_by: krc +creation_date: 2017-10-17T20:54:45Z + +[Term] +id: GO:0120108 +name: DNA-3'-diphospho-5'-guanosine diphosphatase +namespace: molecular_function +def: "Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP." [PMID:26007660] +synonym: "DNA-3'pp5'G guanylate hydrolase" EXACT [] +xref: EC:3.1.12.2 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds +created_by: krc +creation_date: 2017-10-17T22:12:59Z + +[Term] +id: GO:0120109 +name: mitotic telomere clustering and tethering at nuclear periphery +namespace: biological_process +def: "The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle." [PMID:25778919] +is_a: GO:0034397 ! telomere localization +created_by: krc +creation_date: 2017-11-01T18:04:37Z + +[Term] +id: GO:0120110 +name: interphase mitotic telomere clustering +namespace: biological_process +def: "The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope." [PMID:25778919] +comment: It is likely that both intra chromosome telomere clustering and inter-chromosome occur because a single focus is sometimes observed, although this has yet to be proven. +synonym: "mitotic telomere clustering during interphase" EXACT [] +is_a: GO:0034397 ! telomere localization +relationship: part_of GO:0120109 ! mitotic telomere clustering and tethering at nuclear periphery +created_by: krc +creation_date: 2017-11-01T18:09:08Z + +[Term] +id: GO:0120111 +name: neuron projection cytoplasm +namespace: cellular_component +def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha] +is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0043005 ! neuron projection +relationship: part_of GO:0043005 ! neuron projection +created_by: krc +creation_date: 2017-11-01T18:58:12Z + +[Term] +id: GO:0120112 +name: UDP-glucose transmembrane transport into endoplasmic reticulum +namespace: biological_process +def: "The directed movement of UDP-glucose from cytosol to endoplasmic reticulum." [PMID:27587357] +is_a: GO:0015786 ! UDP-glucose transmembrane transport +is_a: GO:0046967 ! cytosol to endoplasmic reticulum transport +created_by: krc +creation_date: 2017-11-02T15:56:51Z + +[Term] +id: GO:0120113 +name: cytoplasm to vacuole transport by the NVT pathway +namespace: biological_process +def: "A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe." [PMID:26365378] +synonym: "cytoplasm to vacuole targeting" BROAD [] +synonym: "cytoplasm-to-vacuole targeting" BROAD [] +synonym: "protein localization by the Nbr1-mediated vacuolar targeting pathway" EXACT [] +synonym: "protein localization by the NVT pathway" EXACT [] +is_a: GO:0006623 ! protein targeting to vacuole +relationship: has_part GO:0006624 ! vacuolar protein processing +created_by: krc +creation_date: 2017-11-03T16:07:55Z + +[Term] +id: GO:0120114 +name: Sm-like protein family complex +namespace: cellular_component +def: "A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles." [GOC:bhm, GOC:krc, PMID:19121818, PMID:27627834] +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2017-11-06T18:46:43Z + +[Term] +id: GO:0120115 +name: Lsm2-8 complex +namespace: cellular_component +def: "A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular the U6 snRNA, and also to unspliced transcripts localized within the nucleus." [GOC:bhm, GOC:krc, PMID:19121818, PMID:23221597, PMID:27627834, PMID:28768202] +xref: IntAct:EBI-16419597 +is_a: GO:0120114 ! Sm-like protein family complex +created_by: krc +creation_date: 2017-11-06T18:56:22Z + +[Term] +id: GO:0120116 +name: glucagon processing +namespace: biological_process +def: "The formation of mature glucagon by proteolysis of the precursor proglucagon." [PMID:28719828] +is_a: GO:0016486 ! peptide hormone processing +created_by: krc +creation_date: 2017-11-08T19:31:42Z + +[Term] +id: GO:0120117 +name: T cell meandering migration +namespace: biological_process +def: "The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs)." [GOC:add, GOC:krc, PMID:25083865] +synonym: "lymph node surveillance" RELATED [] +synonym: "T cell meandering search" EXACT [] +is_a: GO:0072678 ! T cell migration +created_by: krc +creation_date: 2017-11-22T18:13:01Z + +[Term] +id: GO:0120118 +name: flagella connector +namespace: cellular_component +def: "A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum." [PMID:11641501, PMID:15075226, PMID:16954145, PMID:26820516] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. +is_a: GO:0030054 ! cell junction +created_by: krc +creation_date: 2017-12-11T22:24:17Z + +[Term] +id: GO:0120119 +name: flagellum attachment zone +namespace: cellular_component +def: "A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species." [PMID:10361731, PMID:16414276, PMID:17945531, PMID:20541452, PMID:25972344, PMID:2606941, PMID:26746239, PMID:26776656] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. +synonym: "FAZ" RELATED [] +is_a: GO:0070161 ! anchoring junction +created_by: krc +creation_date: 2017-12-11T22:46:43Z + +[Term] +id: GO:0120120 +name: bilobe structure +namespace: cellular_component +def: "A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone)." [PMID:22327007, PMID:22445359, PMID:26540076] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. +synonym: "kinetoplastid flagellar hook complex" EXACT [PMID:26540076] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +created_by: krc +creation_date: 2017-12-11T23:47:20Z + +[Term] +id: GO:0120121 +name: tripartite attachment complex +namespace: cellular_component +def: "A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body." [PMID:12802053, PMID:18059470, PMID:24821793, PMID:27168148] +synonym: "TAC" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +created_by: krc +creation_date: 2017-12-12T00:07:37Z + +[Term] +id: GO:0120122 +name: prolactin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals." [PMID:11015620] +synonym: "prolactin metabolism" EXACT [] +is_a: GO:0034754 ! cellular hormone metabolic process +created_by: krc +creation_date: 2018-01-25T17:28:40Z + +[Term] +id: GO:0120123 +name: ubiquitin activating enzyme complex +namespace: cellular_component +def: "A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate." [GOC:lnp, PMID:9545234] +synonym: "E1 complex" EXACT [GOC:lnp] +synonym: "E1 ubiquitin-activating enzyme" RELATED [GOC:lnp] +xref: IntAct:EBI-16629455 +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular +created_by: krc +creation_date: 2018-01-29T19:28:56Z + +[Term] +id: GO:0120124 +name: membrane fusion priming complex +namespace: cellular_component +def: "A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes." [GOC:lnp, PMID:90153011] +synonym: "GATE-16 complex" EXACT [] +synonym: "LMA1 complex" EXACT [] +xref: IntAct:EBI-16411729 +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2018-02-06T22:22:47Z + +[Term] +id: GO:0120125 +name: PNGase complex +namespace: cellular_component +def: "A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue." [GOC:lnp, PMID:15964983, PMID:16249333] +xref: IntAct:EBI-16422385 +is_a: GO:1905368 ! peptidase complex +created_by: krc +creation_date: 2018-02-12T16:31:57Z + +[Term] +id: GO:0120126 +name: response to copper ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion." [GOC:sl, PMID:24024382] +is_a: GO:0042594 ! response to starvation +created_by: krc +creation_date: 2018-02-12T19:49:19Z + +[Term] +id: GO:0120127 +name: response to zinc ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion." [GOC:sl, PMID:24024381] +is_a: GO:0042594 ! response to starvation +created_by: krc +creation_date: 2018-02-12T19:57:02Z + +[Term] +id: GO:0120132 +name: positive regulation of apoptotic process in bone marrow cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27908889] +synonym: "activation of apoptosis in bone marrow" NARROW [GOC:krc] +synonym: "positive regulation of apoptosis in bone marrow" NARROW [GO:krc] +synonym: "positive regulation of apoptotic process in bone marrow" EXACT [] +synonym: "positive regulation of bone marrow cell apoptosis" EXACT [GOC:krc] +synonym: "positive regulation of bone marrow cell programmed cell death by apoptosis" EXACT [GOC:krc] +synonym: "positive regulation of killing of bone marrow cells" EXACT [GOC:krc] +synonym: "positive regulation of programmed cell death of bone marrow cells by apoptosis" EXACT [GOC:krc] +synonym: "positive regulation of programmed cell death, bone marrow cells" EXACT [GOC:krc] +synonym: "up regulation of apoptosis in bone marrow" EXACT [GOC:krc] +synonym: "up-regulation of apoptosis in bone marrow" EXACT [GOC:krc] +synonym: "upregulation of apoptosis in bone marrow" EXACT [GOC:krc] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0071865 ! regulation of apoptotic process in bone marrow cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071839 ! apoptotic process in bone marrow cell +relationship: positively_regulates GO:0071839 ! apoptotic process in bone marrow cell +created_by: krc +creation_date: 2018-02-19T16:51:46Z + +[Term] +id: GO:0120133 +name: negative regulation of actin cortical patch assembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches." [PMID:19962315] +synonym: "down regulation of actin cortical patch assembly" EXACT [] +synonym: "down-regulation of actin cortical patch assembly" EXACT [] +synonym: "downregulation of actin cortical patch assembly" EXACT [] +synonym: "inhibition of actin cortical patch assembly" NARROW [] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000147 ! actin cortical patch assembly +relationship: negatively_regulates GO:0000147 ! actin cortical patch assembly +created_by: krc +creation_date: 2018-02-20T16:23:53Z + +[Term] +id: GO:0120134 +name: proximal portion of axoneme +namespace: cellular_component +def: "The portion of the axoneme that is close to the base of the cilium." [GOC:krc] +synonym: "proximal part of axoneme" EXACT [GOC:krc] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005930 ! axoneme +created_by: krc +creation_date: 2018-03-10T01:41:06Z + +[Term] +id: GO:0120135 +name: distal portion of axoneme +namespace: cellular_component +def: "The portion of the axoneme that is close to the tip of the cilium." [GOC:krc] +synonym: "distal part of axoneme" EXACT [GOC:krc] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005930 ! axoneme +created_by: krc +creation_date: 2018-03-10T01:45:34Z + +[Term] +id: GO:0120136 +name: dUMP kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + dUMP = ADP + dUDP." [PMID:3010881] +synonym: "ATP:dUMP phosphotransferase activity" EXACT [] +synonym: "deoxyuridine monophosphate kinase activity" EXACT [] +synonym: "dUMP-kinase activity" EXACT [] +is_a: GO:0009041 ! uridylate kinase activity +created_by: krc +creation_date: 2018-03-21T21:16:06Z + +[Term] +id: GO:0120137 +name: positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +namespace: biological_process +def: "Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity." [PMID:23407971] +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0062002 ! regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +relationship: positively_regulates GO:0052885 ! all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity +created_by: krc +creation_date: 2018-03-21T21:59:55Z + +[Term] +id: GO:0120138 +name: regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity." [PMID:17097615] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +relationship: regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +created_by: krc +creation_date: 2018-03-22T16:15:08Z + +[Term] +id: GO:0120139 +name: positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity." [PMID:17097615] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:0120138 ! regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +relationship: positively_regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +created_by: krc +creation_date: 2018-03-22T16:24:20Z + +[Term] +id: GO:0120140 +name: negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity." [PMID:17097615] +is_a: GO:0010923 ! negative regulation of phosphatase activity +is_a: GO:0120138 ! regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +relationship: negatively_regulates GO:0004439 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity +created_by: krc +creation_date: 2018-03-22T16:32:59Z + +[Term] +id: GO:0120141 +name: regulation of ecdysone receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway." [GOC:ha, PMID:23072462] +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:1905957 ! regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +relationship: regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +created_by: krc +creation_date: 2018-03-22T17:10:29Z + +[Term] +id: GO:0120142 +name: positive regulation of ecdysone receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway." [GOC:ha, PMID:23072462] +is_a: GO:0033145 ! positive regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:0120141 ! regulation of ecdysone receptor-mediated signaling pathway +is_a: GO:1905959 ! positive regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +relationship: positively_regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +created_by: krc +creation_date: 2018-03-22T17:25:00Z + +[Term] +id: GO:0120143 +name: negative regulation of ecdysone receptor-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway." [GOC:ha, PMID:23072462] +is_a: GO:0033144 ! negative regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:0120141 ! regulation of ecdysone receptor-mediated signaling pathway +is_a: GO:1905958 ! negative regulation of cellular response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +relationship: negatively_regulates GO:0035076 ! ecdysone receptor-mediated signaling pathway +created_by: krc +creation_date: 2018-03-22T17:28:29Z + +[Term] +id: GO:0120145 +name: protein localization to basal ectoplasmic specialization +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization." [PMID:22872576] +synonym: "protein localisation in basal ectoplasmic specialization" EXACT [GOC:krc] +synonym: "protein localisation to basal ectoplasmic specialization" EXACT [GOC:krc] +synonym: "protein localization in basal ectoplasmic specialization" EXACT [GOC:krc] +is_a: GO:0150105 ! protein localization to cell-cell junction +created_by: krc +creation_date: 2018-03-27T20:16:09Z + +[Term] +id: GO:0120146 +name: sulfatide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group." [GOC:krc, PMID:21525289, PMID:22619219, PMID:22977233, PMID:23574804, PMID:29497057, PMID:3549017, Wikipedia:Sulfatide] +synonym: "3-O-sulfogalactosylceramide binding" EXACT [] +synonym: "SM4 binding" EXACT [] +synonym: "sulfated galactocerebroside binding" EXACT [] +is_a: GO:0051861 ! glycolipid binding +created_by: krc +creation_date: 2018-03-30T20:44:03Z + +[Term] +id: GO:0120147 +name: Formylglycine-generating oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O." [EC:1.8.3.7, RHEA:51152] +xref: EC:1.8.3.7 +xref: MetaCyc:RXN-16226 +xref: RHEA:51152 +is_a: GO:0016670 ! oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor +created_by: krc +creation_date: 2018-04-06T15:38:52Z + +[Term] +id: GO:0120148 +name: host cell centrosome +namespace: cellular_component +def: "A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." [ISBN:0198547684] +synonym: "host centrosome" EXACT [] +is_a: GO:0044163 ! host cytoskeleton +created_by: krc +creation_date: 2018-04-13T15:22:54Z + +[Term] +id: GO:0120149 +name: host cell peroxisome +namespace: cellular_component +def: "A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism." [PMID:9302272] +synonym: "host peroxisome" EXACT [] +is_a: GO:0033648 ! host intracellular membrane-bounded organelle +is_a: GO:0033655 ! host cell cytoplasm part +created_by: krc +creation_date: 2018-04-13T15:36:40Z + +[Term] +id: GO:0120150 +name: regulation of mitotic actomyosin contractile ring disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly." [PMID:19109423] +synonym: "regulation of mitotic actomyosin ring disassembly" EXACT [PMID:19109423] +synonym: "regulation of mitotic CAR disassembly" EXACT [PMID:19109423] +synonym: "regulation of mitotic constriction ring disassembly" EXACT [PMID:19109423] +synonym: "regulation of mitotic contractile actomyosin ring disassembly" EXACT [PMID:19109423] +synonym: "regulation of mitotic cytokinetic ring disassembly" EXACT [PMID:19109423] +is_a: GO:0110020 ! regulation of actomyosin structure organization +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990274 ! mitotic actomyosin contractile ring disassembly +relationship: regulates GO:1990274 ! mitotic actomyosin contractile ring disassembly +created_by: krc +creation_date: 2018-04-24T15:06:28Z + +[Term] +id: GO:0120151 +name: positive regulation of mitotic actomyosin contractile ring disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly." [PMID:19109423] +synonym: "positive regulation of mitotic actomyosin ring disassembly" EXACT [PMID:19109423] +synonym: "positive regulation of mitotic CAR disassembly" EXACT [PMID:19109423] +synonym: "positive regulation of mitotic constriction ring disassembly" EXACT [PMID:19109423] +synonym: "positive regulation of mitotic contractile actomyosin ring disassembly" EXACT [PMID:19109423] +synonym: "positive regulation of mitotic cytokinetic ring disassembly" EXACT [PMID:19109423] +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0120150 ! regulation of mitotic actomyosin contractile ring disassembly +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990274 ! mitotic actomyosin contractile ring disassembly +relationship: positively_regulates GO:1990274 ! mitotic actomyosin contractile ring disassembly +created_by: krc +creation_date: 2018-04-24T15:06:51Z + +[Term] +id: GO:0120152 +name: calcium-dependent outer dynein arm binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an outer dynein arm in the presence of calcium." [GOC:krc, PMID:18620543] +is_a: GO:0048306 ! calcium-dependent protein binding +created_by: krc +creation_date: 2018-04-27T16:33:39Z + +[Term] +id: GO:0120153 +name: calcium-dependent carbohydrate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any carbohydrate in the presence of calcium." [PMID:25912189] +is_a: GO:0030246 ! carbohydrate binding +created_by: krc +creation_date: 2018-04-27T16:42:21Z + +[Term] +id: GO:0120154 +name: negative regulation of ERBB4 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway." [PMID:15219672] +is_a: GO:1901185 ! negative regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038130 ! ERBB4 signaling pathway +relationship: negatively_regulates GO:0038130 ! ERBB4 signaling pathway +created_by: krc +creation_date: 2018-05-01T17:12:23Z + +[Term] +id: GO:0120155 +name: MIH complex +namespace: cellular_component +def: "A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins." [GOC:rn, PMID:24413167, PMID:24895401] +synonym: "Mlc1p-Iqg1p-Hof1p complex" EXACT [GOC:rn] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005935 ! cellular bud neck +created_by: krc +creation_date: 2018-05-01T17:50:23Z + +[Term] +id: GO:0120157 +name: PAR polarity complex +namespace: cellular_component +def: "A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC." [GOC:lnp, PMID:11113154, PMID:18005931, PMID:22500799, PMID:28682236] +comment: "This tripartite complex named PAR6/PAR3/aPKC is conserved from worms to vertebrates" (PMID:18005931). In yeast, the components are BEM1, CDC24, and CLA4. +synonym: "apical polarity complex" EXACT [GOC:lnp] +synonym: "BEM1-CDC24-CLA4 complex" NARROW [] +synonym: "Cdc42p GEF-PAK complex" NARROW [] +synonym: "PAR3-PAR6-atypical PKC" NARROW [GOC:lnp] +synonym: "PAR3/PAR6/aPKC" NARROW [GOC:lnp] +synonym: "PAR6-PAR3-aPKC complex" NARROW [PMID:18005931] +xref: ComplexPortal:CPX-3462 +is_a: GO:1902554 ! serine/threonine protein kinase complex +created_by: krc +creation_date: 2018-05-11T15:41:30Z + +[Term] +id: GO:0120158 +name: positive regulation of collagen catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb] +synonym: "activation of collagen catabolic process" NARROW [GOC:dph, GOC:tb] +synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] +synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] +synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0010710 ! regulation of collagen catabolic process +is_a: GO:0010714 ! positive regulation of collagen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030574 ! collagen catabolic process +relationship: positively_regulates GO:0030574 ! collagen catabolic process +created_by: krc +creation_date: 2018-05-11T16:31:42Z + +[Term] +id: GO:0120159 +name: rRNA pseudouridine synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [PMID:28432181] +synonym: "16S rRNA pseudouridine(516) synthase" NARROW [EC:5.4.99.19] +synonym: "21S rRNA pseudouridine(2819) synthase" NARROW [EC:5.4.99.43] +synonym: "23S rRNA pseudouridine(1911/1915/1917) synthase" NARROW [EC:5.4.99.23] +synonym: "23S rRNA pseudouridine(2457) synthase" NARROW [EC:5.4.99.20] +synonym: "23S rRNA pseudouridine(2604) synthase" NARROW [EC:5.4.99.21] +synonym: "23S rRNA pseudouridine(2605) synthase" NARROW [EC:5.4.99.22] +synonym: "23S rRNA pseudouridine(746) synthase" NARROW [EC:5.4.99.29] +synonym: "23S rRNA pseudouridine(955/2504/2580) synthase" NARROW [EC:5.4.99.24] +xref: EC:5.4.99.19 +xref: EC:5.4.99.20 +xref: EC:5.4.99.21 +xref: EC:5.4.99.22 +xref: EC:5.4.99.23 +xref: EC:5.4.99.24 +xref: EC:5.4.99.29 +xref: EC:5.4.99.43 +is_a: GO:0009982 ! pseudouridine synthase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: krc +creation_date: 2018-05-11T21:24:19Z + +[Term] +id: GO:0120160 +name: intraciliary transport particle A binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an intraciliary transport particle A (IFT A) complex." [PMID:20889716] +synonym: "IFT A complex binding" RELATED [] +synonym: "intraciliary transport complex A binding" EXACT [] +synonym: "intraflagellar transport complex A binding" EXACT [] +synonym: "intraflagellar transport particle A binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2018-05-11T22:28:11Z + +[Term] +id: GO:0120161 +name: regulation of cold-induced thermogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cold-induced thermogenesis." [PMID:27876809] +synonym: "regulation of CIT" RELATED [] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0106106 ! cold-induced thermogenesis +relationship: regulates GO:0106106 ! cold-induced thermogenesis +created_by: krc +creation_date: 2018-05-14T17:03:19Z + +[Term] +id: GO:0120162 +name: positive regulation of cold-induced thermogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis." [PMID:27876809] +synonym: "positive regulation of CIT" RELATED [] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0120161 ! regulation of cold-induced thermogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0106106 ! cold-induced thermogenesis +relationship: positively_regulates GO:0106106 ! cold-induced thermogenesis +created_by: krc +creation_date: 2018-05-14T17:14:51Z + +[Term] +id: GO:0120163 +name: negative regulation of cold-induced thermogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis." [PMID:27876809] +synonym: "negative regulation of CIT" RELATED [] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0120161 ! regulation of cold-induced thermogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0106106 ! cold-induced thermogenesis +relationship: negatively_regulates GO:0106106 ! cold-induced thermogenesis +created_by: krc +creation_date: 2018-05-14T17:18:59Z + +[Term] +id: GO:0120164 +name: conidium germination +namespace: biological_process +def: "The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination." [DOI:10.1128/9781555815523.ch10, PMID:10835388, PMID:11377860, PMID:17950638, PMID:18944978, PMID:25063657, PMID:27355215, PMID:9529886] +is_a: GO:0009847 ! spore germination +property_value: RO:0002161 NCBITaxon:147554 +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:241407 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:451866 +property_value: RO:0002161 NCBITaxon:4930 +created_by: krc +creation_date: 2018-05-17T17:03:32Z + +[Term] +id: GO:0120165 +name: perithecium development +namespace: biological_process +def: "The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck." [DOI:10.1007/978-3-642-00286-1_2, PMID:125266, PMID:19547974, PMID:20739093, PMID:25311923] +is_a: GO:0030582 ! reproductive fruiting body development +created_by: krc +creation_date: 2018-05-17T17:17:44Z + +[Term] +id: GO:0120166 +name: protoperithecium formation +namespace: biological_process +def: "The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium." [DOI:10.1007/978-3-642-00286-1_2, PMID:125266, PMID:20739093, PMID:25311923, PMID:4410944, PMID:6235211, PMID:6235212] +comment: Note that this term represents protoperithecium formation across homothallic and heterothallic species that do not have the same mechanism. +is_a: GO:0030582 ! reproductive fruiting body development +created_by: krc +creation_date: 2018-05-17T17:27:16Z + +[Term] +id: GO:0120168 +name: detection of hot stimulus involved in thermoception +namespace: biological_process +def: "The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception." [PMID:21335241] +synonym: "sensory detection of heat stimulus during thermoception" EXACT [] +synonym: "sensory detection of hot stimulus during thermoception" EXACT [] +synonym: "sensory transduction of heat stimulus during thermoception" EXACT [] +synonym: "sensory transduction of hot stimulus during thermoception" EXACT [] +synonym: "thermoception, sensory detection of heat stimulus" EXACT [] +synonym: "thermoception, sensory detection of hot stimulus" EXACT [] +synonym: "thermoception, sensory transduction of heat stimulus" EXACT [] +synonym: "thermoception, sensory transduction of hot stimulus" EXACT [] +is_a: GO:0050960 ! detection of temperature stimulus involved in thermoception +relationship: part_of GO:0062036 ! sensory perception of hot stimulus +created_by: krc +creation_date: 2018-05-21T20:35:47Z + +[Term] +id: GO:0120169 +name: detection of cold stimulus involved in thermoception +namespace: biological_process +def: "The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception." [PMID:21335241] +synonym: "sensory detection of cold stimulus during thermoception" EXACT [] +synonym: "sensory transduction of cold stimulus during thermoception" EXACT [] +synonym: "thermoception, sensory detection of cold stimulus" EXACT [] +synonym: "thermoception, sensory transduction of cold stimulus" EXACT [] +is_a: GO:0050960 ! detection of temperature stimulus involved in thermoception +relationship: part_of GO:0062035 ! sensory perception of cold stimulus +created_by: krc +creation_date: 2018-05-21T20:36:05Z + +[Term] +id: GO:0120170 +name: intraciliary transport particle B binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an intraciliary transport particle B (IFT B) complex." [PMID:20889716] +synonym: "IFT B complex binding" RELATED [] +synonym: "intraciliary transport complex B binding" EXACT [] +synonym: "intraflagellar transport complex B binding" EXACT [] +synonym: "intraflagellar transport particle B binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: krc +creation_date: 2018-05-11T22:28:11Z + +[Term] +id: GO:0120171 +name: Cdc24p-Far1p-Gbetagamma complex +namespace: cellular_component +def: "A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit)." [PMID:10087263] +synonym: "CDC24-FAR1-BG complex" EXACT [GOC:bm] +synonym: "CDC24-FAR1-Gbetagamma complex" EXACT [GOC:bm] +synonym: "Cdc24p-Far1p-BG complex" EXACT [GOC:rn, PMID:10087263] +xref: ComplexPortal:CPX-977 +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2018-05-31T17:11:20Z + +[Term] +id: GO:0120172 +name: positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly." [GOC:vw, PMID:24798735] +is_a: GO:0120173 ! regulation of actin filament bundle convergence involved in mitotic contractile ring assembly +is_a: GO:1903482 ! positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903478 ! actin filament bundle convergence involved in mitotic contractile ring assembly +relationship: positively_regulates GO:1903478 ! actin filament bundle convergence involved in mitotic contractile ring assembly +created_by: krc +creation_date: 2018-05-31T17:54:35Z + +[Term] +id: GO:0120173 +name: regulation of actin filament bundle convergence involved in mitotic contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly." [GOC:vw, PMID:24798735] +is_a: GO:1903480 ! regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903478 ! actin filament bundle convergence involved in mitotic contractile ring assembly +relationship: regulates GO:1903478 ! actin filament bundle convergence involved in mitotic contractile ring assembly +created_by: krc +creation_date: 2018-05-31T18:08:01Z + +[Term] +id: GO:0120174 +name: stress-induced homeostatically regulated protein degradation pathway +namespace: biological_process +def: "A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway." [GOC:rl, GOC:rn, PMID:29861160] +comment: Note, although the SHRED pathway may contain some components in common with ER-associated protein degradation (ERAD) pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10 do not appear to be involved, and as such these pathways are currently considered to be distinct. ERAD pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M) and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by subsequent substrate ubiquitination and proteosome-mediated degradation. In contrast the SHRED pathway, although inducible by stress, targets diverse ER membrane and cytosolic proteins as well as numerous other native proteins in the absence of stress. In the SHRED pathway an Nma111p serine protease-mediated cleavage results in the generation of a Roq1p fragment that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. SHRED is also considered to be distinct from the endoplasmic reticulum unfolded protein response (GO:0030968), a process by which ER stress activates the ER membrane protein Ire1p, resulting in splicing of the HAC1 mRNA, followed by Hac1p-mediated up-regulation of UPR genes. Induction of SHRED does not require IRE1 or HAC1, and as such is currently considered to be distinct. +synonym: "SHRED pathway" RELATED [GOC:rn] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0033554 ! cellular response to stress +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +created_by: krc +creation_date: 2018-06-07T16:16:43Z + +[Term] +id: GO:0120175 +name: regulation of torso signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the torso signaling pathway." [GOC:ha, PMID:23732470] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008293 ! torso signaling pathway +relationship: regulates GO:0008293 ! torso signaling pathway +created_by: krc +creation_date: 2018-06-07T16:47:42Z + +[Term] +id: GO:0120176 +name: positive regulation of torso signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the torso signaling pathway." [GOC:ha, PMID:23732470] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0120175 ! regulation of torso signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008293 ! torso signaling pathway +relationship: positively_regulates GO:0008293 ! torso signaling pathway +created_by: krc +creation_date: 2018-06-07T16:52:52Z + +[Term] +id: GO:0120177 +name: negative regulation of torso signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway." [GOC:ha, PMID:23732470] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0120175 ! regulation of torso signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008293 ! torso signaling pathway +relationship: negatively_regulates GO:0008293 ! torso signaling pathway +created_by: krc +creation_date: 2018-06-07T16:58:08Z + +[Term] +id: GO:0120178 +name: steroid hormone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +created_by: krc +creation_date: 2019-05-20T22:34:00Z + +[Term] +id: GO:0120179 +name: adherens junction disassembly +namespace: biological_process +def: "The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GOC:aruk, GOC:bc, PMID:25490267] +is_a: GO:0034332 ! adherens junction organization +is_a: GO:0150147 ! cell-cell junction disassembly +created_by: krc +creation_date: 2018-07-12T17:29:56Z + +[Term] +id: GO:0120180 +name: cell-substrate junction disassembly +namespace: biological_process +def: "The disaggregation of a cell-substrate junction into its constituent components." [GOC:aruk, GOC:bc, PMID:25490267] +is_a: GO:0150115 ! cell-substrate junction organization +is_a: GO:0150146 ! cell junction disassembly +created_by: krc +creation_date: 2018-07-12T17:33:35Z + +[Term] +id: GO:0120181 +name: focal adhesion disassembly +namespace: biological_process +def: "The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity." [PMID:25490267] +is_a: GO:0120180 ! cell-substrate junction disassembly +created_by: krc +creation_date: 2018-07-12T17:37:14Z + +[Term] +id: GO:0120182 +name: regulation of focal adhesion disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components." [PMID:25490267] +is_a: GO:0150116 ! regulation of cell-substrate junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0120181 ! focal adhesion disassembly +relationship: regulates GO:0120181 ! focal adhesion disassembly +created_by: krc +creation_date: 2018-07-12T17:44:29Z + +[Term] +id: GO:0120183 +name: positive regulation of focal adhesion disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components." [PMID:25490267] +is_a: GO:0120182 ! regulation of focal adhesion disassembly +is_a: GO:0150117 ! positive regulation of cell-substrate junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0120181 ! focal adhesion disassembly +relationship: positively_regulates GO:0120181 ! focal adhesion disassembly +created_by: krc +creation_date: 2018-07-12T18:27:19Z + +[Term] +id: GO:0120184 +name: negative regulation of focal adhesion disassembly +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components." [PMID:25490267] +is_a: GO:0120182 ! regulation of focal adhesion disassembly +is_a: GO:0150118 ! negative regulation of cell-substrate junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0120181 ! focal adhesion disassembly +relationship: negatively_regulates GO:0120181 ! focal adhesion disassembly +created_by: krc +creation_date: 2018-07-12T18:30:06Z + +[Term] +id: GO:0120185 +name: MBF transcription complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex." [PMID:9303312] +synonym: "DSC1 transcription factor complex assembly" EXACT [] +synonym: "MBF complex assembly" EXACT [] +synonym: "Mlu1-box binding factor assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: krc +creation_date: 2018-07-13T23:21:43Z + +[Term] +id: GO:0120186 +name: negative regulation of protein localization to chromatin +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] +synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905634 ! regulation of protein localization to chromatin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071168 ! protein localization to chromatin +relationship: negatively_regulates GO:0071168 ! protein localization to chromatin +created_by: krc +creation_date: 2018-07-14T00:19:32Z + +[Term] +id: GO:0120187 +name: positive regulation of protein localization to chromatin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] +synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905634 ! regulation of protein localization to chromatin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071168 ! protein localization to chromatin +relationship: positively_regulates GO:0071168 ! protein localization to chromatin +created_by: krc +creation_date: 2018-07-14T00:21:28Z + +[Term] +id: GO:0120188 +name: regulation of bile acid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:0044070 ! regulation of anion transport +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032782 ! bile acid secretion +relationship: regulates GO:0032782 ! bile acid secretion +created_by: krc +creation_date: 2018-07-16T22:28:58Z + +[Term] +id: GO:0120189 +name: positive regulation of bile acid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] +is_a: GO:0032892 ! positive regulation of organic acid transport +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0120188 ! regulation of bile acid secretion +is_a: GO:1903793 ! positive regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032782 ! bile acid secretion +relationship: positively_regulates GO:0032782 ! bile acid secretion +created_by: krc +creation_date: 2018-07-16T22:36:17Z + +[Term] +id: GO:0120190 +name: negative regulation of bile acid secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] +is_a: GO:0032891 ! negative regulation of organic acid transport +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0120188 ! regulation of bile acid secretion +is_a: GO:1903792 ! negative regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032782 ! bile acid secretion +relationship: negatively_regulates GO:0032782 ! bile acid secretion +created_by: krc +creation_date: 2018-07-16T22:38:34Z + +[Term] +id: GO:0120191 +name: negative regulation of termination of RNA polymerase II transcription +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription." [GOC:krc, GOC:vw, PMID:29899453] +synonym: "down regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:krc] +synonym: "down regulation of RNA polymerase II transcription termination" EXACT [GOC:krc] +synonym: "down regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:krc] +synonym: "down regulation of termination of RNA polymerase II transcription" EXACT [GOC:krc] +synonym: "down regulation of transcription termination from Pol II promoter" EXACT [GOC:krc] +synonym: "down regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:krc] +synonym: "down-regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:krc] +synonym: "down-regulation of RNA polymerase II transcription termination" EXACT [GOC:krc] +synonym: "down-regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:krc] +synonym: "down-regulation of termination of RNA polymerase II transcription" EXACT [GOC:krc] +synonym: "down-regulation of transcription termination from Pol II promoter" EXACT [GOC:krc] +synonym: "down-regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:krc] +synonym: "downregulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:krc] +synonym: "downregulation of RNA polymerase II transcription termination" EXACT [GOC:krc] +synonym: "downregulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:krc] +synonym: "downregulation of termination of RNA polymerase II transcription" EXACT [GOC:krc] +synonym: "downregulation of transcription termination from Pol II promoter" EXACT [GOC:krc] +synonym: "downregulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:krc] +synonym: "negative regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:krc] +synonym: "negative regulation of RNA polymerase II transcription termination" EXACT [GOC:krc] +synonym: "negative regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:krc] +synonym: "negative regulation of transcription termination from Pol II promoter" EXACT [GOC:krc] +synonym: "negative regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:krc] +synonym: "repression of RNA 3'-end formation by RNA polymerase II" NARROW [GOC:krc] +synonym: "repression of RNA polymerase II transcription termination" NARROW [GOC:krc] +synonym: "repression of RNA polymerase II transcription termination factor activity" RELATED [GOC:krc] +synonym: "repression of termination of RNA polymerase II transcription" NARROW [GOC:krc] +synonym: "repression of transcription termination from Pol II promoter" NARROW [GOC:krc] +synonym: "repression of transcription termination from RNA polymerase II promoter" NARROW [GOC:krc] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0060567 ! negative regulation of DNA-templated transcription, termination +is_a: GO:1904594 ! regulation of termination of RNA polymerase II transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006369 ! termination of RNA polymerase II transcription +relationship: negatively_regulates GO:0006369 ! termination of RNA polymerase II transcription +created_by: krc +creation_date: 2018-07-18T15:43:40Z + +[Term] +id: GO:0120192 +name: tight junction assembly +namespace: biological_process +def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." [GOC:rl] +synonym: "occluding cell junction assembly" EXACT [GOC:rl] +synonym: "occluding junction assembly" EXACT [GOC:rl] +is_a: GO:0007043 ! cell-cell junction assembly +is_a: GO:0120193 ! tight junction organization +created_by: krc +creation_date: 2018-08-14T22:48:05Z + +[Term] +id: GO:0120193 +name: tight junction organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." [GOC:krc, GOC:rl] +synonym: "occluding cell junction organization" EXACT [GOC:rl] +synonym: "occluding junction organization" EXACT [] +is_a: GO:0045216 ! cell-cell junction organization +created_by: krc +creation_date: 2018-08-14T23:05:40Z + +[Term] +id: GO:0120194 +name: regulation of anther dehiscence +namespace: biological_process +def: "Any process involved in the dehiscence of an anther to release the pollen grains contained within it." [GOC:lr, PMID:30911018] +is_a: GO:0009909 ! regulation of flower development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009901 ! anther dehiscence +relationship: regulates GO:0009901 ! anther dehiscence +created_by: krc +creation_date: 2019-04-09T21:40:39Z + +[Term] +id: GO:0120195 +name: positive regulation of anther dehiscence +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anther dehiscence." [GOC:lr, PMID:30911018] +is_a: GO:0009911 ! positive regulation of flower development +is_a: GO:0120194 ! regulation of anther dehiscence +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009901 ! anther dehiscence +relationship: positively_regulates GO:0009901 ! anther dehiscence +created_by: krc +creation_date: 2019-04-09T21:58:31Z + +[Term] +id: GO:0120196 +name: negative regulation of anther dehiscence +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence." [GOC:lr, PMID:30911018] +is_a: GO:0009910 ! negative regulation of flower development +is_a: GO:0120194 ! regulation of anther dehiscence +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009901 ! anther dehiscence +relationship: negatively_regulates GO:0009901 ! anther dehiscence +created_by: krc +creation_date: 2019-04-09T22:03:16Z + +[Term] +id: GO:0120197 +name: mucociliary clearance +namespace: biological_process +def: "The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways." [GOC:krc, PMID:24119105, PMID:27864314] +synonym: "MCC" RELATED [PMID:24119105, PMID:27864314] +synonym: "MCT" RELATED [PMID:28289722] +synonym: "mucociliary transport" EXACT [PMID:28289722] +is_a: GO:0003016 ! respiratory system process +is_a: GO:0003351 ! epithelial cilium movement involved in extracellular fluid movement +created_by: krc +creation_date: 2019-04-26T16:16:50Z + +[Term] +id: GO:0120198 +name: positive regulation of imaginal disc-derived wing size +namespace: biological_process +def: "Any process that increases the size of an imaginal disc-derived wing." [GOC:ha, PIMD:23485686] +is_a: GO:0044719 ! regulation of imaginal disc-derived wing size +created_by: krc +creation_date: 2019-04-30T21:47:06Z + +[Term] +id: GO:0120199 +name: cone photoreceptor outer segment +namespace: cellular_component +def: "The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins." [GOC:krc, GOC:pde, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0001750 ! photoreceptor outer segment +created_by: krc +creation_date: 2019-05-07T22:23:28Z + +[Term] +id: GO:0120200 +name: rod photoreceptor outer segment +namespace: cellular_component +def: "The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins." [GOC:krc, GOC:pde, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0001750 ! photoreceptor outer segment +created_by: krc +creation_date: 2019-05-07T22:47:20Z + +[Term] +id: GO:0120201 +name: cone photoreceptor disc membrane +namespace: cellular_component +def: "Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane." [GOC:krc, GOC:pde, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0060170 ! ciliary membrane +is_a: GO:0097381 ! photoreceptor disc membrane +created_by: krc +creation_date: 2019-05-07T23:17:43Z + +[Term] +id: GO:0120202 +name: rod photoreceptor disc membrane +namespace: cellular_component +def: "Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment." [GOC:krc, GOC:pde, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0030659 ! cytoplasmic vesicle membrane +is_a: GO:0097381 ! photoreceptor disc membrane +created_by: krc +creation_date: 2019-05-07T23:27:06Z + +[Term] +id: GO:0120203 +name: rod photoreceptor disc lumen +namespace: cellular_component +def: "The volume enclosed by the membrane of a rod photoreceptor cell disc membrane." [GOC:krc, GOC:pde, PMID:19501669, PMID:26574505, PMID:6771304] +is_a: GO:0043233 ! organelle lumen +relationship: part_of GO:0120200 ! rod photoreceptor outer segment +created_by: krc +creation_date: 2019-05-07T23:49:50Z + +[Term] +id: GO:0120204 +name: methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2." [PMID:31043749] +xref: RHEA:60132 +xref: RHEA:60136 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +created_by: krc +creation_date: 2019-05-10T15:58:47Z + +[Term] +id: GO:0120205 +name: photoreceptor proximal connecting cilium +namespace: cellular_component +def: "The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR." [GOC:krc, PMID:29899041] +synonym: "PCC" RELATED [PMID:29899041] +synonym: "photoreceptor PCC" RELATED [PMID:29899041] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032391 ! photoreceptor connecting cilium +created_by: krc +creation_date: 2019-05-10T22:47:08Z + +[Term] +id: GO:0120206 +name: photoreceptor distal connecting cilium +namespace: cellular_component +def: "The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability." [GOC:krc, PMID:29899041] +synonym: "DCC" RELATED [PMID:29899041] +synonym: "photoreceptor DCC" RELATED [PMID:29899041] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0032391 ! photoreceptor connecting cilium +created_by: krc +creation_date: 2019-05-10T22:54:05Z + +[Term] +id: GO:0120207 +name: endocytosis, site selection +namespace: biological_process +def: "The process of selecting and or marking the position where endocytosis will occur." [GOC:vw, PMID:30044717] +is_a: GO:1990778 ! protein localization to cell periphery +relationship: part_of GO:0006897 ! endocytosis +created_by: krc +creation_date: 2019-05-15T21:25:49Z + +[Term] +id: GO:0120208 +name: telodendria +namespace: cellular_component +def: "Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons." [GOC:cvs, GOC:krc, PMID:11074451, PMID:11506430, PMID:14755521, PMID:1646866, PMID:20533354, PMID:29127712, PMID:451992, PMID:8390352] +is_a: GO:0043005 ! neuron projection +created_by: krc +creation_date: 2019-05-20T23:50:28Z + +[Term] +id: GO:0120209 +name: cone telodendria +namespace: cellular_component +def: "Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina." [GOC:cvs, GOC:krc, PMID:29127712] +is_a: GO:0120208 ! telodendria +created_by: krc +creation_date: 2019-05-21T00:01:34Z + +[Term] +id: GO:0120210 +name: rod telodendria +namespace: cellular_component +def: "Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina." [GOC:cvs, GOC:krc, PMID:14755521] +is_a: GO:0120208 ! telodendria +created_by: krc +creation_date: 2019-05-21T00:34:22Z + +[Term] +id: GO:0120211 +name: proacrosomal vesicle fusion +namespace: biological_process +def: "Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome." [GOC:krc, PMID:29991750] +is_a: GO:0006906 ! vesicle fusion +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0001675 ! acrosome assembly +created_by: krc +creation_date: 2019-05-22T17:12:55Z + +[Term] +id: GO:0120212 +name: sperm head-tail coupling apparatus +namespace: cellular_component +def: "A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head." [GOC:krc, PMID:24415959, PMID:30032984] +synonym: "head-tail coupling apparatus" EXACT [PMID:24415959, PMID:30032984] +synonym: "HTCA" RELATED [PMID:24415959] +is_a: GO:0110165 ! cellular anatomical entity +created_by: krc +creation_date: 2019-06-07T23:08:46Z + +[Term] +id: GO:0120213 +name: regulation of histidine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histidine biosynthetic process." [GOC:krc] +synonym: "regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "regulation of histidine formation" EXACT [GOC:krc] +synonym: "regulation of histidine synthesis" EXACT [GOC:krc] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000105 ! histidine biosynthetic process +relationship: regulates GO:0000105 ! histidine biosynthetic process +created_by: krc +creation_date: 2019-06-27T20:55:42Z + +[Term] +id: GO:0120214 +name: negative regulation of histidine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process." [GOC:krc] +synonym: "down regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "down regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "down regulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "down regulation of histidine formation" EXACT [GOC:krc] +synonym: "down regulation of histidine synthesis" EXACT [GOC:krc] +synonym: "down-regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "down-regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "down-regulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "down-regulation of histidine formation" EXACT [GOC:krc] +synonym: "down-regulation of histidine synthesis" EXACT [GOC:krc] +synonym: "downregulation of histidine anabolism" EXACT [GOC:krc] +synonym: "downregulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "downregulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "downregulation of histidine formation" EXACT [GOC:krc] +synonym: "downregulation of histidine synthesis" EXACT [GOC:krc] +synonym: "inhibition of histidine anabolism" NARROW [GOC:krc] +synonym: "inhibition of histidine biosynthesis" NARROW [GOC:krc] +synonym: "inhibition of histidine biosynthetic process" NARROW [GOC:krc] +synonym: "inhibition of histidine formation" NARROW [GOC:krc] +synonym: "inhibition of histidine synthesis" NARROW [GOC:krc] +synonym: "negative regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "negative regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "negative regulation of histidine formation" EXACT [GOC:krc] +synonym: "negative regulation of histidine synthesis" EXACT [GOC:krc] +is_a: GO:0120213 ! regulation of histidine biosynthetic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000105 ! histidine biosynthetic process +relationship: negatively_regulates GO:0000105 ! histidine biosynthetic process +created_by: krc +creation_date: 2019-06-27T20:56:35Z + +[Term] +id: GO:0120215 +name: positive regulation of histidine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process." [GOC:krc] +synonym: "activation of histidine anabolism" NARROW [GOC:krc] +synonym: "activation of histidine biosynthesis" NARROW [GOC:krc] +synonym: "activation of histidine biosynthetic process" NARROW [GOC:krc] +synonym: "activation of histidine formation" NARROW [GOC:krc] +synonym: "activation of histidine synthesis" NARROW [GOC:krc] +synonym: "positive regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "positive regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "positive regulation of histidine formation" EXACT [GOC:krc] +synonym: "positive regulation of histidine synthesis" EXACT [GOC:krc] +synonym: "up regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "up regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "up regulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "up regulation of histidine formation" EXACT [GOC:krc] +synonym: "up regulation of histidine synthesis" EXACT [GOC:krc] +synonym: "up-regulation of histidine anabolism" EXACT [GOC:krc] +synonym: "up-regulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "up-regulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "up-regulation of histidine formation" EXACT [GOC:krc] +synonym: "up-regulation of histidine synthesis" EXACT [GOC:krc] +synonym: "upregulation of histidine anabolism" EXACT [GOC:krc] +synonym: "upregulation of histidine biosynthesis" EXACT [GOC:krc] +synonym: "upregulation of histidine biosynthetic process" EXACT [GOC:krc] +synonym: "upregulation of histidine formation" EXACT [GOC:krc] +synonym: "upregulation of histidine synthesis" EXACT [GOC:krc] +is_a: GO:0120213 ! regulation of histidine biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000105 ! histidine biosynthetic process +relationship: positively_regulates GO:0000105 ! histidine biosynthetic process +created_by: krc +creation_date: 2019-06-27T20:57:28Z + +[Term] +id: GO:0120216 +name: matrilin complex +namespace: cellular_component +def: "A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer." [GOC:bhm, PMID:10367731, PMID:15075323, PMID:9699631] +synonym: "matrilin family complex" RELATED [GOC:bhm] +synonym: "matrilin-1 complex" NARROW [GOC:bhm] +synonym: "matrilin-2 complex" NARROW [GOC:bhm] +synonym: "matrilin-3 complex" NARROW [GOC:bhm] +synonym: "matrilin-4 complex" NARROW [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: krc +creation_date: 2019-07-09T22:05:11Z + +[Term] +id: GO:0120217 +name: DNA gyrase complex +namespace: cellular_component +def: "A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB)." [GOC:bhm, GOC:krc, PMID:1657531, PMID:20675723, Wikipedia:DNA_gyrase] +synonym: "topoisomerase II complex" EXACT [GOC:bhm, GOC:krc, Wikipedia:DNA_gyrase] +is_a: GO:0009330 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: krc +creation_date: 2019-08-20T18:36:35Z + +[Term] +id: GO:0120218 +name: host interaction involved in quorum sensing +namespace: biological_process +def: "A quorum sensing process that is modulated by some interaction with a host cell or organism." [GOC:krc, GOC:mlg, PMID:11780122, PMID:16630813] +is_a: GO:0009372 ! quorum sensing +created_by: krc +creation_date: 2019-11-01T21:52:08Z + +[Term] +id: GO:0120219 +name: subapical part of cell +namespace: cellular_component +def: "The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina." [GOC:krc, PMID:29891944] +synonym: "subapical region of cell" EXACT [GOC:krc] +is_a: GO:0110165 ! cellular anatomical entity +created_by: krc +creation_date: 2019-11-15T17:08:22Z + +[Term] +id: GO:0120220 +name: basal body patch +namespace: cellular_component +def: "The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster." [GOC:krc, PMID:20164345, PMID:20685736, PMID:29891944] +synonym: "centriolar patch" EXACT [GOC:krc, PMID:29891944] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045177 ! apical part of cell +created_by: krc +creation_date: 2019-11-15T17:19:24Z + +[Term] +id: GO:0120221 +name: maintenance of ciliary planar beating movement pattern +namespace: biological_process +def: "Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement." [GOC:krc, PMID:26506310] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. +is_a: GO:0003352 ! regulation of cilium movement +created_by: krc +creation_date: 2019-12-10T21:34:54Z + +[Term] +id: GO:0120222 +name: regulation of blastocyst development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001824 ! blastocyst development +relationship: regulates GO:0001824 ! blastocyst development +created_by: krc +creation_date: 2020-02-17T19:59:20Z + +[Term] +id: GO:0120223 +name: larynx morphogenesis +namespace: biological_process +def: "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] +synonym: "laryngeal morphogenesis" EXACT [GOC:krc, PMID:28177282] +is_a: GO:0009887 ! animal organ morphogenesis +relationship: part_of GO:0120224 ! larynx development +created_by: krc +creation_date: 2020-02-22T01:42:04Z + +[Term] +id: GO:0120224 +name: larynx development +namespace: biological_process +def: "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] +is_a: GO:0048513 ! animal organ development +relationship: part_of GO:0060541 ! respiratory system development +created_by: krc +creation_date: 2020-02-24T17:13:10Z + +[Term] +id: GO:0140007 +name: KICSTOR complex +namespace: cellular_component +def: "A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2." [PMID:28199306] +is_a: GO:0032991 ! protein-containing complex +created_by: pg +creation_date: 2017-03-10T12:47:30Z + +[Term] +id: GO:0140009 +name: L-aspartate import across plasma membrane +namespace: biological_process +def: "The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000069, PMID:7914198] +is_a: GO:0001504 ! neurotransmitter uptake +is_a: GO:0070778 ! L-aspartate transmembrane transport +is_a: GO:0089718 ! amino acid import across plasma membrane +created_by: pg +creation_date: 2017-03-13T10:59:51Z + +[Term] +id: GO:0140010 +name: D-aspartate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of D-aspartate from one side of a membrane to the other." [GO_REF:0000070, PMID:7914198] +is_a: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity +is_a: GO:0042943 ! D-amino acid transmembrane transporter activity +relationship: part_of GO:0070777 ! D-aspartate transport +created_by: pg +creation_date: 2017-03-13T11:15:15Z + +[Term] +id: GO:0140013 +name: meiotic nuclear division +namespace: biological_process +def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324] +is_a: GO:0000280 ! nuclear division +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0000280 ! nuclear division +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: pg +creation_date: 2017-03-23T09:40:00Z + +[Term] +id: GO:0140014 +name: mitotic nuclear division +namespace: biological_process +def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684] +subset: goslim_chembl +subset: goslim_generic +is_a: GO:0000280 ! nuclear division +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0000280 ! nuclear division +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: pg +creation_date: 2017-03-23T14:44:23Z + +[Term] +id: GO:0140018 +name: regulation of cytoplasmic translational fidelity +namespace: biological_process +def: "Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code." [PMID:22768388] +is_a: GO:0006450 ! regulation of translational fidelity +is_a: GO:1900247 ! regulation of cytoplasmic translational elongation +created_by: pg +creation_date: 2017-04-06T12:27:10Z + +[Term] +id: GO:0140020 +name: DNA methyltransferase complex +namespace: cellular_component +def: "A protein complex that possesses DNA methyltransferase activity." [PMID:20939822, PMID:24947342] +is_a: GO:0034708 ! methyltransferase complex +created_by: pg +creation_date: 2017-04-06T19:12:09Z + +[Term] +id: GO:0140021 +name: mitochondrial ADP transmembrane transport +namespace: biological_process +def: "The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:2541251] +is_a: GO:0015866 ! ADP transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: pg +creation_date: 2017-04-10T15:14:34Z + +[Term] +id: GO:0140022 +name: cnida +namespace: cellular_component +def: "A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria." [Wikipedia:Cnida#Structure_and_function] +synonym: "cnidae (plural)" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +created_by: cjm +creation_date: 2017-04-12T15:12:20Z + +[Term] +id: GO:0140023 +name: tRNA adenosine deamination to inosine +namespace: biological_process +def: "The removal of an amine group from an adenosine to produce inosine within a tRNA molecule." [PMID:27974624] +synonym: "A-to-I tRNA editing" EXACT [] +is_a: GO:0006400 ! tRNA modification +created_by: pg +creation_date: 2017-04-26T05:56:51Z + +[Term] +id: GO:0140024 +name: plus-end-directed endosome transport along mitotic spindle midzone microtubule +namespace: biological_process +def: "The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination." [PMID:24803650, PMID:25706234] +is_a: GO:0072383 ! plus-end-directed vesicle transport along microtubule +created_by: pg +creation_date: 2017-04-29T11:34:23Z + +[Term] +id: GO:0140025 +name: contractile vacuole tethering involved in discharge +namespace: biological_process +def: "The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion." [PMID:22323285] +synonym: "contractile vacuole tethering to plasma membrane" NARROW [] +is_a: GO:0006903 ! vesicle targeting +is_a: GO:0090522 ! vesicle tethering involved in exocytosis +intersection_of: GO:0006903 ! vesicle targeting +intersection_of: part_of GO:0070177 ! contractile vacuole discharge +relationship: part_of GO:0070177 ! contractile vacuole discharge +created_by: pg +creation_date: 2017-05-02T09:50:10Z + +[Term] +id: GO:0140026 +name: contractile vacuole dissociation from plasma membrane +namespace: biological_process +def: "The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network." [PMID:22323285] +synonym: "contractile vacuole detethering from plasma membrane" EXACT [] +is_a: GO:0016192 ! vesicle-mediated transport +created_by: pg +creation_date: 2017-05-02T10:16:12Z + +[Term] +id: GO:0140027 +name: establishment of contractile vacuole localization +namespace: biological_process +def: "The directed movement of the contractile vacuole to a specific location." [PMID:19687255] +is_a: GO:0051656 ! establishment of organelle localization +created_by: pg +creation_date: 2017-05-02T10:23:26Z + +[Term] +id: GO:0140028 +name: pore formation during contractile vacuole discharge +namespace: biological_process +def: "The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes." [PMID:22323285, Wikipedia:Exocytosis] +is_a: GO:0140029 ! exocytic process +relationship: part_of GO:0070177 ! contractile vacuole discharge +created_by: pg +creation_date: 2017-05-15T12:20:27Z + +[Term] +id: GO:0140029 +name: exocytic process +namespace: biological_process +def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis] +subset: gocheck_do_not_annotate +is_a: GO:0009987 ! cellular process +intersection_of: GO:0009987 ! cellular process +intersection_of: part_of GO:0006887 ! exocytosis +relationship: part_of GO:0006887 ! exocytosis +created_by: pg +creation_date: 2017-05-15T13:20:45Z + +[Term] +id: GO:0140030 +name: modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon post-translation modification of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require a post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term. +synonym: "modified protein binding" RELATED [] +is_a: GO:0005515 ! protein binding +created_by: pg +creation_date: 2017-05-17T11:50:41Z + +[Term] +id: GO:0140031 +name: phosphorylation-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon phosphorylation of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require phosphorylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of phosphorylation. It may be that the phosphorylation causes a conformational change that allows binding of the protein to another region; this type of phosphorylation-dependent protein binding is valid for annotation to this term. +is_a: GO:0140030 ! modification-dependent protein binding +created_by: pg +creation_date: 2017-05-17T15:15:19Z + +[Term] +id: GO:0140032 +name: glycosylation-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon glycosylation of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require glycosylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of glycosylation. It may be that the glycosylation causes a conformational change that allows binding of the protein to another region; this type of glycosylation-dependent protein binding is valid for annotation to this term. +is_a: GO:0140030 ! modification-dependent protein binding +created_by: pg +creation_date: 2017-05-17T15:20:50Z + +[Term] +id: GO:0140033 +name: acetylation-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon acetylation of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require acetylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of acetylation. It may be that the acetylation causes a conformational change that allows binding of the protein to another region; this type of acetylation-dependent protein binding is valid for annotation to this term. +is_a: GO:0140030 ! modification-dependent protein binding +created_by: pg +creation_date: 2017-05-17T15:35:43Z + +[Term] +id: GO:0140034 +name: methylation-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon methylation of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require methylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of methylation. It may be that the methylation causes a conformational change that allows binding of the protein to another region; this type of methylation-dependent protein binding is valid for annotation to this term. +is_a: GO:0140030 ! modification-dependent protein binding +created_by: pg +creation_date: 2017-05-17T15:40:02Z + +[Term] +id: GO:0140035 +name: ubiquitination-like modification-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon modification by a ubiquitin-like protein of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require a ubiquitin-like modification in the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitin-like modification. It may be that the modification causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term. +is_a: GO:0140030 ! modification-dependent protein binding +created_by: pg +creation_date: 2017-05-18T06:11:27Z + +[Term] +id: GO:0140036 +name: ubiquitin-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require ubiquitination of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitination. It may be that the ubiquitination causes a conformational change that allows binding of the protein to another region; this type of ubiquitination-dependent protein binding is valid for annotation to this term. +is_a: GO:0140035 ! ubiquitination-like modification-dependent protein binding +created_by: pg +creation_date: 2017-05-18T06:29:14Z + +[Term] +id: GO:0140037 +name: sumo-dependent protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein upon sumoylation of the target protein." [PMID:26060076] +comment: This term should only be used when the binding is shown to require sumoylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of sumoylation. It may be that the sumoylation causes a conformational change that allows binding of the protein to another region; this type of sumoylation-dependent protein binding is valid for annotation to this term. +is_a: GO:0140035 ! ubiquitination-like modification-dependent protein binding +created_by: pg +creation_date: 2017-05-18T06:29:27Z + +[Term] +id: GO:0140039 +name: cell-cell adhesion in response to extracellular stimulus +namespace: biological_process +def: "The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus." [PMID:14996911] +is_a: GO:0098609 ! cell-cell adhesion +intersection_of: GO:0098609 ! cell-cell adhesion +intersection_of: part_of GO:0031668 ! cellular response to extracellular stimulus +relationship: part_of GO:0031668 ! cellular response to extracellular stimulus +created_by: pg +creation_date: 2017-05-24T11:37:30Z + +[Term] +id: GO:0140040 +name: mitochondrial polycistronic RNA processing +namespace: biological_process +def: "The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs." [PMID:20211597] +is_a: GO:0031426 ! polycistronic mRNA processing +is_a: GO:0090615 ! mitochondrial mRNA processing +intersection_of: GO:0031426 ! polycistronic mRNA processing +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: pg +creation_date: 2017-06-16T07:18:38Z + +[Term] +id: GO:0140041 +name: cellular detoxification of methylglyoxal +namespace: biological_process +def: "Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal." [PMID:15042280] +is_a: GO:0009438 ! methylglyoxal metabolic process +is_a: GO:0110095 ! cellular detoxification of aldehyde +relationship: part_of GO:0097238 ! cellular response to methylglyoxal +created_by: pg +creation_date: 2017-06-16T09:43:30Z + +[Term] +id: GO:0140042 +name: lipid droplet formation +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts of a lipid droplet." [PMID:28011631] +synonym: "adiposome formation" EXACT [] +synonym: "lipid body formation" EXACT [] +synonym: "lipid particle formation" EXACT [] +is_a: GO:0034389 ! lipid droplet organization +is_a: GO:0070925 ! organelle assembly +relationship: part_of GO:0019915 ! lipid storage +created_by: pg +creation_date: 2017-06-19T09:18:43Z + +[Term] +id: GO:0140043 +name: lipid droplet localization to prospore membrane leading edge +namespace: biological_process +def: "Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge." [PMID:28011631] +synonym: "adiposome localization to ascospore-type prospore membrane leading edge" EXACT [] +synonym: "adiposome localization to forespore membrane leading edge" RELATED [] +synonym: "adiposome localization to FSM membrane leading edge" EXACT [] +synonym: "lipid body localization to ascospore-type prospore membrane leading edge" EXACT [] +synonym: "lipid body localization to forespore membrane leading edge" RELATED [] +synonym: "lipid body localization to FSM membrane leading edge" EXACT [] +synonym: "lipid particle localization to ascospore-type prospore membrane leading edge" EXACT [] +synonym: "lipid particle localization to forespore membrane leading edge" RELATED [] +synonym: "lipid particle localization to FSM membrane leading edge" EXACT [] +is_a: GO:0010876 ! lipid localization +created_by: pg +creation_date: 2017-06-19T09:20:13Z + +[Term] +id: GO:0140048 +name: manganese ion export across plasma membrane +namespace: biological_process +def: "The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region." [PMID:25319704] +synonym: "manganese ion export from cell" EXACT [] +is_a: GO:0071421 ! manganese ion transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +created_by: pg +creation_date: 2017-06-23T14:25:00Z + +[Term] +id: GO:0140049 +name: regulation of endocardial cushion to mesenchymal transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:21778427] +is_a: GO:0062042 ! regulation of cardiac epithelial to mesenchymal transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090500 ! endocardial cushion to mesenchymal transition +relationship: regulates GO:0090500 ! endocardial cushion to mesenchymal transition +created_by: pg +creation_date: 2017-06-23T15:57:00Z + +[Term] +id: GO:0140050 +name: negative regulation of endocardial cushion to mesenchymal transition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:21778427] +is_a: GO:0062044 ! negative regulation of cardiac epithelial to mesenchymal transition +is_a: GO:0140049 ! regulation of endocardial cushion to mesenchymal transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090500 ! endocardial cushion to mesenchymal transition +relationship: negatively_regulates GO:0090500 ! endocardial cushion to mesenchymal transition +created_by: pg +creation_date: 2017-06-26T09:02:27Z + +[Term] +id: GO:0140051 +name: positive regulation of endocardial cushion to mesenchymal transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:21778427] +is_a: GO:0062043 ! positive regulation of cardiac epithelial to mesenchymal transition +is_a: GO:0140049 ! regulation of endocardial cushion to mesenchymal transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090500 ! endocardial cushion to mesenchymal transition +relationship: positively_regulates GO:0090500 ! endocardial cushion to mesenchymal transition +created_by: pg +creation_date: 2017-06-26T09:11:03Z + +[Term] +id: GO:0140052 +name: cellular response to oxidised low-density lipoprotein particle stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus." [GOC:aruk, GOC:BHF, PMID:20037584, PMID:27607416] +synonym: "cellular response to ox-LDL particle stimulus" EXACT [] +synonym: "cellular response to oxidised LDL particle stimulus" EXACT [] +synonym: "cellular response to oxidized LDL particle stimulus" EXACT [] +synonym: "cellular response to oxidized low-density lipoprotein particle stimulus" EXACT [] +synonym: "cellular response to oxLDL particle stimulus" EXACT [] +is_a: GO:0055094 ! response to lipoprotein particle +is_a: GO:0071402 ! cellular response to lipoprotein particle stimulus +created_by: pg +creation_date: 2017-06-26T09:40:00Z + +[Term] +id: GO:0140053 +name: mitochondrial gene expression +namespace: biological_process +def: "The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [PMID:27058308] +subset: goslim_pombe +is_a: GO:0010467 ! gene expression +intersection_of: GO:0010467 ! gene expression +intersection_of: occurs_in GO:0005739 ! mitochondrion +relationship: occurs_in GO:0005739 ! mitochondrion +created_by: pg +creation_date: 2017-06-26T10:57:45Z + +[Term] +id: GO:0140056 +name: organelle localization by membrane tethering +namespace: biological_process +def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684] +subset: goslim_pombe +is_a: GO:0022406 ! membrane docking +is_a: GO:0051640 ! organelle localization +created_by: pg +creation_date: 2017-06-27T09:58:51Z + +[Term] +id: GO:0140057 +name: vacuole-mitochondria membrane tethering +namespace: biological_process +def: "The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles." [PMID:27875684] +is_a: GO:0140056 ! organelle localization by membrane tethering +created_by: pg +creation_date: 2017-06-27T10:31:12Z + +[Term] +id: GO:0140058 +name: neuron projection arborization +namespace: biological_process +def: "The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:aruk, GOC:bc, PMID:17114044, PMID:23270857, PMID:23764288] +synonym: "branching morphogenesis of a neurite" RELATED [] +synonym: "branching morphogenesis of a neuron projection" RELATED [] +synonym: "neurite arborization" EXACT [] +synonym: "neurite branching" EXACT [GOC:aruk, GOC:bc, PMID:17114044] +synonym: "neuron projection branching" EXACT [GOC:aruk, GOC:bc, PMID:17114044] +is_a: GO:0048812 ! neuron projection morphogenesis +created_by: pg +creation_date: 2017-07-12T12:25:31Z + +[Term] +id: GO:0140059 +name: dendrite arborization +namespace: biological_process +def: "The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches." [GOC:aruk, GOC:bc, PMID:23270857] +is_a: GO:0048813 ! dendrite morphogenesis +is_a: GO:0140058 ! neuron projection arborization +created_by: pg +creation_date: 2017-07-12T15:12:07Z + +[Term] +id: GO:0140060 +name: axon arborization +namespace: biological_process +def: "The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches." [GOC:aruk, GOC:bc, PMID:23764288] +is_a: GO:0007409 ! axonogenesis +is_a: GO:0140058 ! neuron projection arborization +created_by: pg +creation_date: 2017-07-12T15:17:22Z + +[Term] +id: GO:0140061 +name: 5-hydroxymethylcytosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2." [PMID:27918559] +synonym: "5hmC dioxygenase" EXACT [] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +created_by: pg +creation_date: 2017-07-20T09:54:50Z + +[Term] +id: GO:0140062 +name: 5-formylcytosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2." [PMID:27918559] +synonym: "5fC dioxygenase" EXACT [] +is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity +created_by: pg +creation_date: 2017-07-20T09:57:16Z + +[Term] +id: GO:0140064 +name: peptide crotonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide." [PMID:25818647] +synonym: "protein crotonyltransferase activity" RELATED [] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: pg +creation_date: 2017-07-20T16:40:57Z + +[Term] +id: GO:0140065 +name: peptide butyryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide." [PMID:27105113] +synonym: "protein butyryltransferase activity" RELATED [] +is_a: GO:0016410 ! N-acyltransferase activity +created_by: pg +creation_date: 2017-07-20T16:46:49Z + +[Term] +id: GO:0140066 +name: peptidyl-lysine crotonylation +namespace: biological_process +def: "The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid." [PMID:25818647, Wikipedia:crotonyl] +is_a: GO:0043543 ! protein acylation +created_by: pg +creation_date: 2017-07-20T16:48:58Z + +[Term] +id: GO:0140067 +name: peptidyl-lysine butyrylation +namespace: biological_process +def: "The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid." [PMID:27105113, Wikipedia:butyryl] +is_a: GO:0043543 ! protein acylation +created_by: pg +creation_date: 2017-07-20T16:52:19Z + +[Term] +id: GO:0140068 +name: histone crotonyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone." [PMID:25818647] +is_a: GO:0140064 ! peptide crotonyltransferase activity +created_by: pg +creation_date: 2017-07-20T16:55:16Z + +[Term] +id: GO:0140069 +name: histone butyryltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone." [PMID:27105113] +is_a: GO:0140065 ! peptide butyryltransferase activity +created_by: pg +creation_date: 2017-07-20T16:56:33Z + +[Term] +id: GO:0140074 +name: cardiac endothelial to mesenchymal transition +namespace: biological_process +def: "A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes." [GOC:BHF, GOC:nc, PMID:16162442, PMID:26053665] +synonym: "EndMT" EXACT [PMID:28181491] +synonym: "EndoMT" EXACT [] +is_a: GO:0048762 ! mesenchymal cell differentiation +created_by: pg +creation_date: 2017-07-21T09:39:49Z + +[Term] +id: GO:0140075 +name: regulation of lipoprotein transport +namespace: biological_process +def: "Any process that controls lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] +is_a: GO:0051223 ! regulation of protein transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0042953 ! lipoprotein transport +relationship: regulates GO:0042953 ! lipoprotein transport +created_by: pg +creation_date: 2017-07-21T15:35:47Z + +[Term] +id: GO:0140076 +name: negative regulation of lipoprotein transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:0140075 ! regulation of lipoprotein transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0042953 ! lipoprotein transport +relationship: negatively_regulates GO:0042953 ! lipoprotein transport +created_by: pg +creation_date: 2017-07-21T15:39:50Z + +[Term] +id: GO:0140077 +name: positive regulation of lipoprotein transport +namespace: biological_process +def: "Any process that activates or increases the rate or extent of lipoprotein transport." [GOC:BHF, GOC:BHF_miRNA, GOC:RPH, PMID:26501192] +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:0140075 ! regulation of lipoprotein transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0042953 ! lipoprotein transport +relationship: positively_regulates GO:0042953 ! lipoprotein transport +created_by: pg +creation_date: 2017-07-21T15:41:54Z + +[Term] +id: GO:0140078 +name: class I DNA-(apurinic or apyrimidinic site) endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate." [PMID:1698278, Wikipedia:AP_endonuclease] +synonym: "AP endonuclease class I activity" RELATED [] +synonym: "AP site-DNA 5'-phosphomonoester-lyase activity" EXACT [] +synonym: "class I DNA-(apurinic or apyrimidinic site) lyase activity" EXACT [] +synonym: "DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity" EXACT [] +synonym: "DNA-(apurinic or apyrimidinic site) lyase activity" EXACT [] +xref: EC:4.2.99.18 +xref: MetaCyc:4.2.99.18-RXN +is_a: GO:0003906 ! DNA-(apurinic or apyrimidinic site) endonuclease activity +is_a: GO:0016835 ! carbon-oxygen lyase activity +created_by: pg +creation_date: 2017-07-24T11:33:34Z + +[Term] +id: GO:0140080 +name: class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity +namespace: molecular_function +def: "Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH." [PMID:2519777, Wikipedia:AP_endonuclease] +synonym: "endonuclease III" RELATED [] +synonym: "endonuclease IV" RELATED [] +is_a: GO:0003906 ! DNA-(apurinic or apyrimidinic site) endonuclease activity +is_a: GO:0016889 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters +created_by: pg +creation_date: 2017-07-24T11:48:18Z + +[Term] +id: GO:0140081 +name: glycosylated region protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a glycosylated region of a protein." [GOC:pg] +is_a: GO:0005515 ! protein binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: pg +creation_date: 2017-07-25T10:58:31Z + +[Term] +id: GO:0140082 +name: SUMO-ubiquitin ligase activity +namespace: molecular_function +def: "Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue." [PMID:28552615] +is_a: GO:0061665 ! SUMO ligase activity +created_by: pg +creation_date: 2017-08-08T14:46:50Z + +[Term] +id: GO:0140083 +name: protein-DNA unloading ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate , this reaction drives the unwinding of the DNA helix and drives the removal of a protein or protein complex from a DNA molecule, by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction." [PMID:28552615] +is_a: GO:0016887 ! ATPase activity +created_by: pg +creation_date: 2017-08-08T14:50:27Z + +[Term] +id: GO:0140084 +name: sexual macrocyst formation +namespace: biological_process +def: "The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum." [PMID:16592095, PMID:20089169] +synonym: "macrocyst formation" RELATED [] +synonym: "sexual fusion" RELATED [] +is_a: GO:0019953 ! sexual reproduction +created_by: pg +creation_date: 2017-08-14T20:11:03Z + +[Term] +id: GO:0140090 +name: membrane curvature sensor activity +namespace: molecular_function +def: "Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins." [PMID:25898166] +is_a: GO:0008289 ! lipid binding +created_by: pg +creation_date: 2017-08-19T20:37:54Z + +[Term] +id: GO:0140091 +name: mBAF complex +namespace: cellular_component +def: "A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof." [GO:bhm, PMID:11175787, PMID:12620226, PMID:15525990, PMID:8804307, PMID:8895581] +synonym: "muscle-specific BAF complex" EXACT [] +synonym: "muscle-specific SWI/SNF complex" EXACT [] +synonym: "muscle-type BAF complex" EXACT [] +synonym: "muscle-type SWI/SNF complex" EXACT [] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: pg +creation_date: 2017-09-05T09:20:45Z + +[Term] +id: GO:0140092 +name: bBAF complex +namespace: cellular_component +def: "A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180." [GOC:bhm, PMID:12368262, PMID:12620226, PMID:15525990, PMID:17640523, PMID:17920018, PMID:8804307, PMID:8895581] +synonym: "brain-specific BAF complex" EXACT [] +synonym: "brain-specific SWI/SNF complex" EXACT [] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: pg +creation_date: 2017-09-05T09:22:41Z + +[Term] +id: GO:0140093 +name: esBAF complex +namespace: cellular_component +def: "An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C." [GOC:bhm, PMID:19279218, PMID:19279220, PMID:2620226, PMID:8804307, PMID:8895581] +synonym: "embryonic stem cell-specific BAF complex" EXACT [] +synonym: "embryonic stem cell-specific SWI/SNF complex" EXACT [] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: pg +creation_date: 2017-09-05T09:23:51Z + +[Term] +id: GO:0140096 +name: catalytic activity, acting on a protein +namespace: molecular_function +def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] +is_a: GO:0003824 ! catalytic activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-14T10:32:59Z + +[Term] +id: GO:0140097 +name: catalytic activity, acting on DNA +namespace: molecular_function +def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring\,GOC\:pdt] +is_a: GO:0003824 ! catalytic activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-14T12:03:51Z + +[Term] +id: GO:0140098 +name: catalytic activity, acting on RNA +namespace: molecular_function +def: "Catalytic activity that acts to modify RNA." [GOC:molecular_function_refactoring\,GOC\:pdt] +is_a: GO:0003824 ! catalytic activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-14T12:05:21Z + +[Term] +id: GO:0140101 +name: catalytic activity, acting on a tRNA +namespace: molecular_function +def: "Catalytic activity that acts to modify a tRNA." [GOC:molecular_function_refactoring, GOC:pdt] +is_a: GO:0140098 ! catalytic activity, acting on RNA +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-15T18:41:41Z + +[Term] +id: GO:0140102 +name: catalytic activity, acting on a rRNA +namespace: molecular_function +def: "Catalytic activity that acts to modify a ribosomal RNA." [GOC:molecular_function_refactoring, GOC:pdt] +is_a: GO:0140098 ! catalytic activity, acting on RNA +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-15T19:00:57Z + +[Term] +id: GO:0140103 +name: catalytic activity, acting on a glycoprotein +namespace: molecular_function +def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] +is_a: GO:0140096 ! catalytic activity, acting on a protein +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14225 xsd:anyURI +created_by: pg +creation_date: 2017-09-15T19:27:54Z + +[Term] +id: GO:0140104 +name: molecular carrier activity +namespace: molecular_function +def: "Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location." [GOC:molecular_function_refactoring, GOC:pdt] +subset: gocheck_do_not_annotate +is_a: GO:0003674 ! molecular_function +relationship: has_part GO:0051536 ! iron-sulfur cluster binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14221 xsd:anyURI +created_by: pg +creation_date: 2017-09-19T13:10:18Z + +[Term] +id: GO:0140105 +name: interleukin-10-mediated signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of interleukin-10 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [PMID:11244051] +synonym: "IL-10-mediated signaling pathway" EXACT [] +synonym: "interleukin-10-mediated signalling pathway" EXACT [] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +created_by: pg +creation_date: 2017-09-22T16:04:42Z + +[Term] +id: GO:0140107 +name: high-affinity potassium ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [PMID:10629185] +is_a: GO:0015079 ! potassium ion transmembrane transporter activity +created_by: pg +creation_date: 2017-10-12T09:54:39Z + +[Term] +id: GO:0140108 +name: high-affinity glucose transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [PMID:25411338] +is_a: GO:0005355 ! glucose transmembrane transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14212 xsd:anyURI +created_by: pg +creation_date: 2017-10-12T10:06:19Z + +[Term] +id: GO:0140110 +name: transcription regulator activity +namespace: molecular_function +def: "A molecular function that controls the rate, timing and/or magnitude of transcription of genetic information. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism." [GOC:pg, GOC:txnOH-2018, Wikipedia:Transcription_factor] +subset: gocheck_do_not_annotate +subset: goslim_flybase_ribbon +subset: goslim_plant +is_a: GO:0003674 ! molecular_function +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/13588 xsd:anyURI +created_by: pg +creation_date: 2017-10-18T07:05:44Z + +[Term] +id: GO:0140111 +name: [choline trimethylamine-lyase]-activating enzyme activity +namespace: molecular_function +def: "Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM)." [PMID:24854437] +xref: MetaCyc:RXN-16470 +is_a: GO:0043364 ! glycyl-radical enzyme activating activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14190 xsd:anyURI +created_by: pg +creation_date: 2017-10-20T13:57:38Z + +[Term] +id: GO:0140112 +name: extracellular vesicle biogenesis +namespace: biological_process +def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435] +synonym: "extracellular vesicle assembly" EXACT [] +is_a: GO:0044085 ! cellular component biogenesis +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14256 xsd:anyURI +created_by: pg +creation_date: 2017-10-23T11:53:42Z + +[Term] +id: GO:0140113 +name: extracellular microvesicle biogenesis +namespace: biological_process +def: "The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding." [PMID:28736435] +synonym: "extracellular microvesicle assembly" RELATED [] +is_a: GO:0140112 ! extracellular vesicle biogenesis +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14256 xsd:anyURI +created_by: pg +creation_date: 2017-10-23T12:00:11Z + +[Term] +id: GO:0140114 +name: cellular detoxification of fluoride +namespace: biological_process +def: "Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] +is_a: GO:1990748 ! cellular detoxification +relationship: part_of GO:1902618 ! cellular response to fluoride +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14391 xsd:anyURI +created_by: pg +creation_date: 2017-10-23T15:39:43Z + +[Term] +id: GO:0140115 +name: export across plasma membrane +namespace: biological_process +def: "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:pg] +synonym: "efflux" BROAD [] +is_a: GO:0055085 ! transmembrane transport +is_a: GO:0140352 ! export from cell +created_by: pg +creation_date: 2017-10-24T14:38:16Z + +[Term] +id: GO:0140116 +name: fluoride export across plasma membrane +namespace: biological_process +def: "The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:vw, PMID:27327046] +is_a: GO:0140115 ! export across plasma membrane +is_a: GO:1903424 ! fluoride transmembrane transport +created_by: pg +creation_date: 2017-10-24T14:51:01Z + +[Term] +id: GO:0140121 +name: Lewy body formation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a Lewy body." [PMID:15158159] +is_a: GO:0070841 ! inclusion body assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14160 xsd:anyURI +created_by: pg +creation_date: 2017-10-25T06:59:12Z + +[Term] +id: GO:0140122 +name: regulation of Lewy body formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Lewy body formation." [GOC:sl] +is_a: GO:0090083 ! regulation of inclusion body assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0140121 ! Lewy body formation +relationship: regulates GO:0140121 ! Lewy body formation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14160 xsd:anyURI +created_by: pg +creation_date: 2017-10-25T07:03:29Z + +[Term] +id: GO:0140123 +name: negative regulation of Lewy body formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation." [GOC:sl] +is_a: GO:0090084 ! negative regulation of inclusion body assembly +is_a: GO:0140122 ! regulation of Lewy body formation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0140121 ! Lewy body formation +relationship: negatively_regulates GO:0140121 ! Lewy body formation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14160 xsd:anyURI +created_by: pg +creation_date: 2017-10-25T07:08:56Z + +[Term] +id: GO:0140124 +name: positive regulation of Lewy body formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Lewy body formation." [GOC:sl] +is_a: GO:0090261 ! positive regulation of inclusion body assembly +is_a: GO:0140122 ! regulation of Lewy body formation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0140121 ! Lewy body formation +relationship: positively_regulates GO:0140121 ! Lewy body formation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14160 xsd:anyURI +created_by: pg +creation_date: 2017-10-25T07:10:14Z + +[Term] +id: GO:0140125 +name: thiamine import across plasma membrane +namespace: biological_process +def: "The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw] +is_a: GO:0071934 ! thiamine transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pg +creation_date: 2017-10-25T11:09:23Z + +[Term] +id: GO:0140131 +name: positive regulation of lymphocyte chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis." [PMID:19255442] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:1901623 ! regulation of lymphocyte chemotaxis +is_a: GO:2000403 ! positive regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048247 ! lymphocyte chemotaxis +relationship: positively_regulates GO:0048247 ! lymphocyte chemotaxis +created_by: pg +creation_date: 2017-11-02T10:26:40Z + +[Term] +id: GO:0140132 +name: iron-sulfur cluster carrier activity +namespace: molecular_function +def: "Binding to an iron-sulfur cluster and delivering it to an acceptor molecule." [PMID:22966982, PMID:29051382] +is_a: GO:0140104 ! molecular carrier activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14539 xsd:anyURI +created_by: pg +creation_date: 2017-11-10T08:55:38Z + +[Term] +id: GO:0140133 +name: suppression by symbiont of host cytokine secretion +namespace: biological_process +def: "Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine secretion in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:23083102] +synonym: "negative regulation by symbiont of host cytokine secretion" EXACT [] +is_a: GO:0052170 ! suppression by symbiont of host innate immune response +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14553 xsd:anyURI +created_by: pg +creation_date: 2017-11-14T07:07:04Z + +[Term] +id: GO:0140135 +name: mechanosensitive cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens in response to a mechanical stress." [GOC:ha, PMID:22343900] +synonym: "mechanically-gated cation channel activity" EXACT [] +is_a: GO:0005261 ! cation channel activity +is_a: GO:0008381 ! mechanosensitive ion channel activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14588 xsd:anyURI +created_by: pg +creation_date: 2017-11-17T12:40:37Z + +[Term] +id: GO:0140140 +name: mitochondrial guanine nucleotide transmembrane transport +namespace: biological_process +def: "The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:vw, PMID:14998997] +is_a: GO:1903716 ! guanine transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: pg +creation_date: 2017-11-24T13:26:17Z + +[Term] +id: GO:0140141 +name: mitochondrial potassium ion transmembrane transport +namespace: biological_process +def: "The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:vw, PMID:20197279] +is_a: GO:0071805 ! potassium ion transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: pg +creation_date: 2017-11-24T13:26:42Z + +[Term] +id: GO:0140142 +name: nucleocytoplasmic carrier activity +namespace: molecular_function +alt_id: GO:0061717 +alt_id: GO:0090631 +def: "Carries substances between the nucleus and the cytoplasm of a cell by moving along with the target protein." [GOC:pg] +subset: gocheck_do_not_annotate +synonym: "miRNA transporter activity" NARROW [] +synonym: "nucleocytoplasmic importin/exportin activity" EXACT [] +synonym: "pre-miRNA transporter activity" NARROW [] +is_a: GO:0005215 ! transporter activity +intersection_of: GO:0005215 ! transporter activity +intersection_of: part_of GO:0006913 ! nucleocytoplasmic transport +relationship: part_of GO:0006913 ! nucleocytoplasmic transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14336 xsd:anyURI +created_by: pg +creation_date: 2017-12-06T13:40:40Z + +[Term] +id: GO:0140145 +name: copper ion export from vacuole +namespace: biological_process +def: "The directed movement of copper ions out of the vacuole across the vacuolar membrane." [GOC:vw, PMID:12244050] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0060003 ! copper ion export +created_by: pg +creation_date: 2017-12-13T15:02:39Z + +[Term] +id: GO:0140146 +name: calcium ion import into vacuole +namespace: biological_process +def: "The directed movement of calcium cations into the vacuole across the vacuolar membrane." [GOC:vw, PMID:8628289] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0060401 ! cytosolic calcium ion transport +is_a: GO:0070588 ! calcium ion transmembrane transport +is_a: GO:1901660 ! calcium ion export +created_by: pg +creation_date: 2017-12-13T15:15:29Z + +[Term] +id: GO:0140147 +name: zinc ion export from vacuole +namespace: biological_process +def: "The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol." [GOC:vw, PMC:PMC203372] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0070839 ! divalent metal ion export +is_a: GO:0071577 ! zinc ion transmembrane transport +created_by: pg +creation_date: 2017-12-13T15:21:10Z + +[Term] +id: GO:0140157 +name: ammonium import across plasma membrane +namespace: biological_process +def: "The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw, PMID:16999738] +is_a: GO:0072488 ! ammonium transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pg +creation_date: 2018-01-26T12:39:56Z + +[Term] +id: GO:0140159 +name: borate export across plasma membrane +namespace: biological_process +def: "The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:vw, PMID:17459946] +is_a: GO:0035445 ! borate transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +created_by: pg +creation_date: 2018-02-02T10:21:37Z + +[Term] +id: GO:0140161 +name: monocarboxylate:sodium symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in)." [GOC:ln, PMID:15322102] +is_a: GO:0005343 ! organic acid:sodium symporter activity +is_a: GO:0015355 ! secondary active monocarboxylate transmembrane transporter activity +created_by: pg +creation_date: 2018-02-05T10:33:55Z + +[Term] +id: GO:0140164 +name: Golgi transport complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the Golgi transport complex, a multisubunit tethering complex of the CATCHR family." [GOC:ha, PMID:28100664] +synonym: "COG complex binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: pg +creation_date: 2018-02-08T11:49:38Z + +[Term] +id: GO:0140192 +name: regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0044057 ! regulation of system process +is_a: GO:0106070 ! regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +relationship: regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:06:38Z + +[Term] +id: GO:0140193 +name: regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0044057 ! regulation of system process +is_a: GO:0071877 ! regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +relationship: regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:08:49Z + +[Term] +id: GO:0140194 +name: negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0140193 ! regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +relationship: negatively_regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:13:02Z + +[Term] +id: GO:0140195 +name: positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0071879 ! positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +is_a: GO:0140193 ! regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +relationship: positively_regulates GO:0086096 ! adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:13:11Z + +[Term] +id: GO:0140196 +name: positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0071879 ! positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +is_a: GO:0106071 ! positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +is_a: GO:0140192 ! regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +relationship: positively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:13:29Z + +[Term] +id: GO:0140199 +name: negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process." [GOC:BHF, GOC:BHF_miRNA, GOC:rph] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0071878 ! negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +is_a: GO:0140192 ! regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +relationship: negatively_regulates GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +created_by: pg +creation_date: 2018-02-15T19:31:23Z + +[Term] +id: GO:0140200 +name: adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate +namespace: biological_process +def: "An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction." [GOC:BHF] +is_a: GO:0086023 ! adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process +intersection_of: GO:0071880 ! adenylate cyclase-activating adrenergic receptor signaling pathway +intersection_of: part_of GO:0002027 ! regulation of heart rate +relationship: has_part GO:0086010 ! membrane depolarization during action potential +relationship: part_of GO:0003062 ! regulation of heart rate by chemical signal +created_by: pg +creation_date: 2018-02-16T14:33:06Z + +[Term] +id: GO:0140201 +name: urea import across plasma membrane +namespace: biological_process +def: "The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol." [PMID:17218313] +is_a: GO:0071918 ! urea transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pg +creation_date: 2018-02-20T10:15:45Z + +[Term] +id: GO:0140202 +name: polyamine import across plasma membrane +namespace: biological_process +def: "The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol." [PMID:17218313] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pg +creation_date: 2018-02-20T10:24:54Z + +[Term] +id: GO:0140203 +name: spermidine import across plasma membrane +namespace: biological_process +def: "The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw] +is_a: GO:0140202 ! polyamine import across plasma membrane +is_a: GO:1903711 ! spermidine transmembrane transport +created_by: pg +creation_date: 2018-02-21T19:10:07Z + +[Term] +id: GO:0140204 +name: pyridoxal import across plasma membrane +namespace: biological_process +def: "The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol." [GOC:vw] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1903090 ! pyridoxal transmembrane transport +created_by: pg +creation_date: 2018-02-21T19:17:27Z + +[Term] +id: GO:0140205 +name: oligopeptide import across plasma membrane +namespace: biological_process +def: "The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol." [PMID:22226946] +is_a: GO:0035672 ! oligopeptide transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: pg +creation_date: 2018-02-22T15:48:21Z + +[Term] +id: GO:0140206 +name: dipeptide import across plasma membrane +namespace: biological_process +def: "The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol." [PMID:22226946] +is_a: GO:0035442 ! dipeptide transmembrane transport +is_a: GO:0140205 ! oligopeptide import across plasma membrane +created_by: pg +creation_date: 2018-02-22T15:49:19Z + +[Term] +id: GO:0140207 +name: tripeptide import across plasma membrane +namespace: biological_process +def: "The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol." [PMID:22226946] +is_a: GO:0035443 ! tripeptide transmembrane transport +is_a: GO:0140205 ! oligopeptide import across plasma membrane +created_by: pg +creation_date: 2018-02-22T15:49:55Z + +[Term] +id: GO:0140208 +name: apoptotic process in response to mitochondrial fragmentation +namespace: biological_process +def: "Any apoptotic process that occurs as a result of mitochondrial fragmentation." [PMID:18940801] +synonym: "apoptosis in response to mitochondrial fragmentation" EXACT [] +is_a: GO:0006915 ! apoptotic process +created_by: pg +creation_date: 2018-03-08T16:54:17Z + +[Term] +id: GO:0140209 +name: zinc ion import into endoplasmic reticulum +namespace: biological_process +def: "The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum." [PMID:11886869, PMID:29529046] +comment: This term covers zinc(2+) import *across* the endoplasmic reticulum membrane through a channel or pore. It does not cover import via vesicle fusion with endoplasmic reticulum membrane, as in this case transport does not involve crossing the membrane. +synonym: "zinc ion import across endoplasmic reticulum" EXACT [] +synonym: "zinc ion import into ER" EXACT [] +synonym: "zinc(2+) import across endoplasmic reticulum" EXACT [] +synonym: "zinc(2+) import into endoplasmic reticulum" EXACT [] +is_a: GO:0046967 ! cytosol to endoplasmic reticulum transport +is_a: GO:0062111 ! zinc ion import into organelle +created_by: pg +creation_date: 2018-03-19T10:40:01Z + +[Term] +id: GO:0140210 +name: protein transport along microtubule to kinetochore +namespace: biological_process +def: "Any process in which a protein is transported to the kinetochore along a microtubule." [PMID:25472718] +is_a: GO:0034501 ! protein localization to kinetochore +is_a: GO:0070199 ! establishment of protein localization to chromosome +is_a: GO:0098840 ! protein transport along microtubule +created_by: pg +creation_date: 2018-03-22T07:05:21Z + +[Term] +id: GO:0140211 +name: folic acid:proton symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid." [PMID:24745983] +xref: TC:2.A.1.50.1 +is_a: GO:0008517 ! folic acid transmembrane transporter activity +is_a: GO:0015295 ! solute:proton symporter activity +created_by: pg +creation_date: 2018-03-30T08:00:09Z + +[Term] +id: GO:0140212 +name: regulation of long-chain fatty acid import into cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell." [PMID:28178239] +is_a: GO:2000191 ! regulation of fatty acid transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0044539 ! long-chain fatty acid import into cell +relationship: regulates GO:0044539 ! long-chain fatty acid import into cell +created_by: pg +creation_date: 2018-04-10T15:10:41Z + +[Term] +id: GO:0140213 +name: negative regulation of long-chain fatty acid import into cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell." [PMID:28178239] +is_a: GO:0140212 ! regulation of long-chain fatty acid import into cell +is_a: GO:2000192 ! negative regulation of fatty acid transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0044539 ! long-chain fatty acid import into cell +relationship: negatively_regulates GO:0044539 ! long-chain fatty acid import into cell +created_by: pg +creation_date: 2018-04-10T15:13:28Z + +[Term] +id: GO:0140214 +name: positive regulation of long-chain fatty acid import into cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell." [PMID:28178239] +is_a: GO:0140212 ! regulation of long-chain fatty acid import into cell +is_a: GO:2000193 ! positive regulation of fatty acid transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0044539 ! long-chain fatty acid import into cell +relationship: positively_regulates GO:0044539 ! long-chain fatty acid import into cell +created_by: pg +creation_date: 2018-04-10T15:15:03Z + +[Term] +id: GO:0140215 +name: regulation of D-aspartate import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol." [PMID:27663541] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0070779 ! D-aspartate import across plasma membrane +relationship: regulates GO:0070779 ! D-aspartate import across plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15041 xsd:anyURI +created_by: pg +creation_date: 2018-04-11T15:33:35Z + +[Term] +id: GO:0140216 +name: negative regulation of D-aspartate import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol." [PMID:27663541] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:0140215 ! regulation of D-aspartate import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0070779 ! D-aspartate import across plasma membrane +relationship: negatively_regulates GO:0070779 ! D-aspartate import across plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15041 xsd:anyURI +created_by: pg +creation_date: 2018-04-11T15:43:25Z + +[Term] +id: GO:0140217 +name: positive regulation of D-aspartate import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol." [PMID:27663541] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:0140215 ! regulation of D-aspartate import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0070779 ! D-aspartate import across plasma membrane +relationship: positively_regulates GO:0070779 ! D-aspartate import across plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15041 xsd:anyURI +created_by: pg +creation_date: 2018-04-11T15:45:22Z + +[Term] +id: GO:0140220 +name: pathogen-containing vacuole +namespace: cellular_component +def: "A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides." [PMID:10560000, PMID:26842840] +synonym: "pathogen inclusion" RELATED [] +synonym: "pathogen-containing compartment" RELATED [] +is_a: GO:0033643 ! host cell part +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15580 xsd:anyURI +created_by: pg +creation_date: 2018-04-20T06:02:14Z + +[Term] +id: GO:0140221 +name: pathogen-containing vacuole membrane +namespace: cellular_component +def: "Host-derived membrane of a pathogen-containing vacuole." [PMID:10560000, PMID:26842840] +synonym: "pathogen inclusion membrane" RELATED [] +synonym: "pathogen-containing compartment membrane" EXACT [] +is_a: GO:0016020 ! membrane +relationship: part_of GO:0140220 ! pathogen-containing vacuole +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15580 xsd:anyURI +created_by: pg +creation_date: 2018-04-20T06:18:25Z + +[Term] +id: GO:0140222 +name: pathogen-containing vacuole lumen +namespace: cellular_component +def: "The enclosed volume within the sealed membrane of a pathogen-containing vacuole." [PMID:10560000, PMID:26842840] +synonym: "lumen of a pathogen-containing vacuole" EXACT [] +synonym: "pathogen inclusion lumen" RELATED [] +synonym: "pathogen-containing compartment lumen" EXACT [] +synonym: "pathogen-containing vacuolar lumen" EXACT [] +is_a: GO:0031974 ! membrane-enclosed lumen +relationship: part_of GO:0140220 ! pathogen-containing vacuole +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15580 xsd:anyURI +created_by: pg +creation_date: 2018-04-20T06:24:02Z + +[Term] +id: GO:0140223 +name: general transcription initiation factor activity +namespace: molecular_function +def: "An activity that contributes to transcription start site selection and transcription initiation." [GOC:txnOH-2018] +comment: General transcription factors assemble with the RNA polymerase at promoter DNA to form the pre-initiation complex (PIC), bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present in all promoters to initiate transcription. The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors belong to the constitutive machinery required for transcription to occur. +subset: gocheck_do_not_annotate +synonym: "basal transcription factor activity" EXACT [] +synonym: "general transcription factor activity" EXACT [] +synonym: "GTF activity" EXACT [] +is_a: GO:0140110 ! transcription regulator activity +relationship: part_of GO:0006351 ! transcription, DNA-templated +created_by: pg +creation_date: 2018-05-24T07:51:23Z + +[Term] +id: GO:0140224 +name: SLAC complex +namespace: cellular_component +def: "A protein complex that regulates Arp2/3 complex-mediated actin nucleation." [GOC:lnp, PMID:22973053] +xref: IntAct:EBI-7506670 +is_a: GO:0032991 ! protein-containing complex +created_by: pg +creation_date: 2018-05-29T09:54:08Z + +[Term] +id: GO:0140225 +name: DNA topoisomerase III-beta-TDRD3 complex +namespace: cellular_component +def: "A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities." [GOC:lnp, PMID:23912945, PMID:28176834] +synonym: "Top3-beta-TDRD3 complex" EXACT [GOC:krc] +is_a: GO:0032991 ! protein-containing complex +created_by: pg +creation_date: 2018-05-29T10:05:33Z + +[Term] +id: GO:0140226 +name: RNA topoisomerase activity +namespace: molecular_function +def: "Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA." [GOC:lnp, PMID:23912945, PMID:27257063] +is_a: GO:0016853 ! isomerase activity +is_a: GO:0140098 ! catalytic activity, acting on RNA +created_by: pg +creation_date: 2018-05-29T11:06:37Z + +[Term] +id: GO:0140227 +name: serotonin-gated cation-selective signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bhm, PMID:25392484, PMID:27764665] +synonym: "5-HT-gated cation-selective signaling pathway" EXACT [] +synonym: "5-HT-gated cation-selective signalling pathway" EXACT [] +synonym: "5-hydroxytryptamine-gated cation-selective signaling pathway" EXACT [] +synonym: "5-hydroxytryptamine-gated cation-selective signalling pathway" EXACT [] +synonym: "serotonin-gated cation-selective signalling pathway" EXACT [] +xref: ComplexPortal:CPX-2175 +xref: ComplexPortal:CPX-271 +xref: ComplexPortal:CPX-272 +xref: ComplexPortal:CPX-273 +xref: ComplexPortal:CPX-274 +xref: ComplexPortal:CPX-275 +xref: ComplexPortal:CPX-276 +xref: ComplexPortal:CPX-277 +xref: ComplexPortal:CPX-278 +is_a: GO:0007210 ! serotonin receptor signaling pathway +is_a: GO:1990806 ! ligand-gated ion channel signaling pathway +created_by: pg +creation_date: 2018-06-02T13:34:51Z + +[Term] +id: GO:0140231 +name: anterograde axonal transport of neurotransmitter receptor complex +namespace: biological_process +def: "The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons." [PMID:28680963] +subset: goslim_synapse +is_a: GO:0097120 ! receptor localization to synapse +is_a: GO:0099637 ! neurotransmitter receptor transport +is_a: GO:0099641 ! anterograde axonal protein transport +created_by: pg +creation_date: 2018-07-09T09:41:37Z + +[Term] +id: GO:0140232 +name: intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential." [PMID:21358644] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +synonym: "intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential" EXACT [] +is_a: GO:0005222 ! intracellular cAMP-activated cation channel activity +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/231 xsd:anyURI +created_by: pg +creation_date: 2018-07-09T11:30:40Z + +[Term] +id: GO:0140233 +name: intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential." [GOC:pvn] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +synonym: "intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential" EXACT [] +is_a: GO:0005222 ! intracellular cAMP-activated cation channel activity +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/231 xsd:anyURI +created_by: pg +creation_date: 2018-07-09T11:31:18Z + +[Term] +id: GO:0140235 +name: RNA polyadenylation at postsynapse +namespace: biological_process +def: "A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse." [PMID:22727665] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0043631 ! RNA polyadenylation +intersection_of: GO:0043631 ! RNA polyadenylation +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse +created_by: pg +creation_date: 2018-07-13T12:03:28Z + +[Term] +id: GO:0140236 +name: translation at presynapse +namespace: biological_process +def: "Translation that occurs at the presynapse." [PMID:27321671] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140241 ! translation at synapse +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0098793 ! presynapse +relationship: occurs_in GO:0098793 ! presynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/216 xsd:anyURI +created_by: pg +creation_date: 2018-07-13T13:00:33Z + +[Term] +id: GO:0140237 +name: translation at presynapse, modulating chemical synaptic transmission +namespace: biological_process +def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission +is_a: GO:0140236 ! translation at presynapse +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: regulates GO:0007268 ! chemical synaptic transmission +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/216 xsd:anyURI +created_by: pg +creation_date: 2018-07-13T13:07:23Z + +[Term] +id: GO:0140238 +name: presynaptic endocytosis +namespace: biological_process +def: "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:24719103] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0006897 ! endocytosis +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099003 ! vesicle-mediated transport in synapse +intersection_of: GO:0006897 ! endocytosis +intersection_of: occurs_in GO:0098793 ! presynapse +relationship: occurs_in GO:0098793 ! presynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/230 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T07:33:55Z + +[Term] +id: GO:0140239 +name: postsynaptic endocytosis +namespace: biological_process +def: "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:12839988] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0006897 ! endocytosis +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099003 ! vesicle-mediated transport in synapse +intersection_of: GO:0006897 ! endocytosis +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/230 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T07:38:27Z + +[Term] +id: GO:0140240 +name: perforant pathway to dendrate granule cell synapse +namespace: cellular_component +def: "A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus." [PMID:22727665, PMID:29199135] +subset: goslim_synapse +synonym: "perforant pathway to DG granule cell synapse" EXACT [] +is_a: GO:0045202 ! synapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/234 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T08:21:43Z + +[Term] +id: GO:0140241 +name: translation at synapse +namespace: biological_process +def: "Translation that occurs at the synapse." [PMID:23083742] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0006412 ! translation +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0045202 ! synapse +relationship: occurs_in GO:0045202 ! synapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T09:23:12Z + +[Term] +id: GO:0140242 +name: translation at postsynapse +namespace: biological_process +def: "Translation that occurs at the postsynapse." [PMID:20427644] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140241 ! translation at synapse +intersection_of: GO:0006412 ! translation +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T09:26:27Z + +[Term] +id: GO:0140243 +name: regulation of translation at synapse +namespace: biological_process +def: "Any process that regulates translation occurring at the synapse." [PMID:20427644] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0045202 ! synapse +intersection_of: regulates GO:0006412 ! translation +relationship: occurs_in GO:0045202 ! synapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T09:38:26Z + +[Term] +id: GO:0140244 +name: regulation of translation at presynapse +namespace: biological_process +def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140243 ! regulation of translation at synapse +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: regulates GO:0006412 ! translation +relationship: occurs_in GO:0098793 ! presynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T09:38:33Z + +[Term] +id: GO:0140245 +name: regulation of translation at postsynapse +namespace: biological_process +def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140243 ! regulation of translation at synapse +intersection_of: GO:0065007 ! biological regulation +intersection_of: occurs_in GO:0098794 ! postsynapse +intersection_of: regulates GO:0006412 ! translation +relationship: occurs_in GO:0098794 ! postsynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T09:38:54Z + +[Term] +id: GO:0140246 +name: protein catabolic process at synapse +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0030163 ! protein catabolic process +relationship: occurs_in GO:0045202 ! synapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/210 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:12:51Z + +[Term] +id: GO:0140247 +name: protein catabolic process at presynapse +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140246 ! protein catabolic process at synapse +relationship: occurs_in GO:0098793 ! presynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/204 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:23:49Z + +[Term] +id: GO:0140249 +name: protein catabolic process at postsynapse +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140246 ! protein catabolic process at synapse +relationship: occurs_in GO:0098794 ! postsynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/204 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:25:04Z + +[Term] +id: GO:0140250 +name: regulation protein catabolic process at synapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0009894 ! regulation of catabolic process +relationship: occurs_in GO:0045202 ! synapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/204 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:34:56Z + +[Term] +id: GO:0140251 +name: regulation protein catabolic process at presynapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140250 ! regulation protein catabolic process at synapse +relationship: occurs_in GO:0098793 ! presynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/204 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:35:39Z + +[Term] +id: GO:0140252 +name: regulation protein catabolic process at postsynapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0140250 ! regulation protein catabolic process at synapse +relationship: occurs_in GO:0098794 ! postsynapse +property_value: term_tracker_item https://github.com/geneontology/synapse/issues/204 xsd:anyURI +created_by: pg +creation_date: 2018-07-15T10:35:56Z + +[Term] +id: GO:0140253 +name: cell-cell fusion +namespace: biological_process +def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion] +synonym: "cell cell fusion" EXACT [] +synonym: "cell fusion" BROAD [] +is_a: GO:0009987 ! cellular process +relationship: has_part GO:0045026 ! plasma membrane fusion +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15939 xsd:anyURI +created_by: pg +creation_date: 2018-08-13T18:38:18Z + +[Term] +id: GO:0140255 +name: regulation of cellular response to phosphate starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation." [PMID:29414789] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0016036 ! cellular response to phosphate starvation +relationship: regulates GO:0016036 ! cellular response to phosphate starvation +created_by: pg +creation_date: 2018-09-07T17:11:42Z + +[Term] +id: GO:0140256 +name: negative regulation of cellular response to phosphate starvation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation." [PMID:29414789] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:0140255 ! regulation of cellular response to phosphate starvation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0016036 ! cellular response to phosphate starvation +relationship: negatively_regulates GO:0016036 ! cellular response to phosphate starvation +created_by: pg +creation_date: 2018-09-07T17:11:42Z + +[Term] +id: GO:0140259 +name: PRC1 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a PRC1 complex." [PMID:15280237] +is_a: GO:0044877 ! protein-containing complex binding +created_by: pg +creation_date: 2018-09-10T16:48:18Z + +[Term] +id: GO:0140260 +name: mitochondrial proton-transporting ATP synthase complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mitochondrial proton-transporting ATP synthase complex." [PMID:12110673] +is_a: GO:0044877 ! protein-containing complex binding +created_by: pg +creation_date: 2018-09-10T19:38:26Z + +[Term] +id: GO:0140261 +name: BCOR complex +namespace: cellular_component +def: "A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10." [PMID:16943429, PMID:22325352, PMID:24515802] +synonym: "BCL6 corepressor (BCOR) complex" EXACT [] +synonym: "BCOR/BCORL1 complex" EXACT [] +synonym: "non-canonical BCOR-PRC1.1 complex" EXACT [] +synonym: "non-canonical PRC1-BCOR complex" EXACT [] +synonym: "PRC1.1 complex" EXACT [] +is_a: GO:0000152 ! nuclear ubiquitin ligase complex +created_by: pg +creation_date: 2018-09-11T09:35:05Z + +[Term] +id: GO:0140262 +name: mRNA cap binding complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a mRNA cap binding complex." [PMID:16938833] +is_a: GO:0044877 ! protein-containing complex binding +created_by: pg +creation_date: 2018-09-12T12:56:16Z + +[Term] +id: GO:0140266 +name: Woronin body +namespace: cellular_component +def: "Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes." [PMID:12640443, PMID:15155882, PMID:18227279, PMID:20707002, PMID:23882222] +is_a: GO:0042579 ! microbody +created_by: pg +creation_date: 2018-09-24T14:53:37Z + +[Term] +id: GO:0140267 +name: viral entry via permeabilization of host membrane +namespace: biological_process +def: "The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm." [PMID:20427561, PMID:25055856] +subset: gocheck_do_not_annotate +is_a: GO:0046718 ! viral entry into host cell +created_by: pg +creation_date: 2018-09-25T14:33:03Z + +[Term] +id: GO:0140268 +name: endoplasmic reticulum-plasma membrane contact site +namespace: cellular_component +def: "A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes." [PMID:23041194, PMID:27955928, PMID:29290560, PMID:29782498, PMID:30012696] +synonym: "endoplasmic reticulum-plasma membrane contact junction" EXACT [] +synonym: "EPCS" EXACT [] +synonym: "ER-plasma membrane contact site" EXACT [] +synonym: "ER-PM contact site" EXACT [] +is_a: GO:0044232 ! organelle membrane contact site +created_by: pg +creation_date: 2018-09-26T09:29:41Z + +[Term] +id: GO:0140270 +name: gluconate import across plasma membrane +namespace: biological_process +def: "The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol." [PMID:10735857] +is_a: GO:0035429 ! gluconate transmembrane transport +is_a: GO:0098704 ! carbohydrate import across plasma membrane +created_by: pg +creation_date: 2018-10-01T08:47:35Z + +[Term] +id: GO:0140271 +name: hexose import across plasma membrane +namespace: biological_process +def: "The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol." [PMID:10735857] +is_a: GO:0008645 ! hexose transmembrane transport +is_a: GO:0098704 ! carbohydrate import across plasma membrane +created_by: pg +creation_date: 2018-10-01T08:49:49Z + +[Term] +id: GO:0140272 +name: exogenous protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein or protein complex from a different species, for example a pathogen molecule binding to a host protein (a complex of two or more proteins that may include other nonprotein molecules)." [PMID:28861068] +comment: Note that as GO captures normal processes, it may be that exogenous proteins interactions are normal for one of the participating species but not the other. Therefore reciprocal annotations should not be made without confirming that it is physiological relevant. +is_a: GO:0005488 ! binding +created_by: pg +creation_date: 2018-10-01T10:03:21Z + +[Term] +id: GO:0140273 +name: repair of mitotic kinetochore microtubule attachment defect +namespace: biological_process +def: "The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected." [PMID:15525536] +synonym: "correction of mitotic kinetochore microtubule attachment defects" EXACT [] +synonym: "repair of mitotic kinetochore microtubule attachment defects" EXACT [] +is_a: GO:0140274 ! repair of kinetochore microtubule attachment defect +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007080 ! mitotic metaphase plate congression +created_by: pg +creation_date: 2018-10-01T11:29:24Z + +[Term] +id: GO:0140274 +name: repair of kinetochore microtubule attachment defect +namespace: biological_process +def: "The cell cycle process where kinetochore microtubule attachment defects are corrected." [PMID:15525536] +synonym: "correction of kinetochore microtubule attachment defects" EXACT [] +synonym: "repair of kinetochore microtubule attachment defects" EXACT [] +is_a: GO:0022402 ! cell cycle process +created_by: pg +creation_date: 2018-10-01T11:30:19Z + +[Term] +id: GO:0140275 +name: MIB complex +namespace: cellular_component +def: "A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1." [PMID:26477565] +synonym: "mitochondrial intermembrane space bridging complex" EXACT [] +synonym: "mitofilin complex" EXACT [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +relationship: part_of GO:0031305 ! integral component of mitochondrial inner membrane +created_by: pg +creation_date: 2018-10-01T17:10:27Z + +[Term] +id: GO:0140276 +name: obsolete pericentric heterochromatin maintenance +namespace: biological_process +alt_id: GO:1902368 +def: "OBSOLETE. Any heterochromatin maintenance that is involved in chromatin silencing at or near a centromere." [GOC:TermGenie, GOC:vw, PMID:21289066] +comment: This term was obsoleted because it represents a phenotype. +synonym: "heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region" RELATED [] +synonym: "heterochromatin maintenance involved in chromatin silencing at centromeric outer repeats" EXACT [GOC:vw] +synonym: "heterochromatin maintenance involved in chromatin silencing at pericentric region" RELATED [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19301 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2013-08-21T10:13:39Z + +[Term] +id: GO:0140278 +name: mitotic division septum assembly +namespace: biological_process +def: "The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material." [PMID:22786806] +is_a: GO:0000917 ! division septum assembly +is_a: GO:1902410 ! mitotic cytokinetic process +created_by: pg +creation_date: 2018-10-08T09:46:11Z + +[Term] +id: GO:0140279 +name: regulation of mitotic division septum assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [PMID:22786806] +synonym: "regulation of division septum formation involved in mitotic cell cycle" EXACT [] +synonym: "regulation of formation of division septum involved in mitotic cell cycle" EXACT [] +synonym: "regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of septin assembly and septum formation involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0032955 ! regulation of division septum assembly +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0140278 ! mitotic division septum assembly +relationship: regulates GO:0140278 ! mitotic division septum assembly +created_by: pg +creation_date: 2018-10-08T09:55:51Z + +[Term] +id: GO:0140280 +name: negative regulation of mitotic division septum assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [PMID:22786806] +synonym: "down regulation of division septum formation involved in mitotic cell cycle" EXACT [] +synonym: "down regulation of formation of division septum involved in mitotic cell cycle" EXACT [] +synonym: "down regulation of mitotic division septum assembly" EXACT [] +synonym: "down regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [] +synonym: "down regulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [] +synonym: "down-regulation of division septum formation involved in mitotic cell cycle" EXACT [] +synonym: "down-regulation of formation of division septum involved in mitotic cell cycle" EXACT [] +synonym: "down-regulation of mitotic division septum assembly" EXACT [] +synonym: "down-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of division septum formation involved in mitotic cell cycle" EXACT [] +synonym: "downregulation of formation of division septum involved in mitotic cell cycle" EXACT [] +synonym: "downregulation of mitotic division septum assembly" EXACT [] +synonym: "downregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "inhibition of division septum formation involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of formation of division septum involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic division septum assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "inhibition of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of division septum formation involved in mitotic cell cycle" EXACT [] +synonym: "negative regulation of formation of division septum involved in mitotic cell cycle" EXACT [] +synonym: "negative regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0010974 ! negative regulation of division septum assembly +is_a: GO:0140279 ! regulation of mitotic division septum assembly +is_a: GO:1903437 ! negative regulation of mitotic cytokinetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0140278 ! mitotic division septum assembly +relationship: negatively_regulates GO:0140278 ! mitotic division septum assembly +created_by: pg +creation_date: 2018-10-08T10:03:22Z + +[Term] +id: GO:0140281 +name: positive regulation of mitotic division septum assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis." [PMID:22786806] +synonym: "activation of division septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "activation of formation of division septum involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "activation of mitotic division septum assembly" EXACT [GOC:TermGenie] +synonym: "activation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "activation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of division septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of formation of division septum involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic division septum assembly" EXACT [] +synonym: "positive regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of septin assembly and septum formation involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of division septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of formation of division septum involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic division septum assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of division septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of formation of division septum involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic division septum assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of division septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of formation of division septum involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of septin assembly and septum formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0010973 ! positive regulation of division septum assembly +is_a: GO:0140279 ! regulation of mitotic division septum assembly +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0140278 ! mitotic division septum assembly +relationship: positively_regulates GO:0140278 ! mitotic division septum assembly +created_by: pg +creation_date: 2018-10-08T10:03:30Z + +[Term] +id: GO:0140282 +name: carbon-nitrogen ligase activity on lipid II +namespace: molecular_function +def: "Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate." [PMID:22291598, PMID:30093673, PMID:30154570] +synonym: "carbon-nitrogen ligase activity on lipid II" EXACT [] +synonym: "L-glutamate--lipid II transaminase activity" EXACT [] +synonym: "undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl pentapeptide amidotransferase (glutamine-hydrolyzing) activity" EXACT [] +xref: RHEA:57928 +is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor +created_by: pg +creation_date: 2018-10-08T19:12:57Z + +[Term] +id: GO:0140284 +name: endoplasmic reticulum-endosome membrane contact site +namespace: cellular_component +def: "A contact site between the endoplasmic reticulum membrane and the endosome membrane." [PMID:24105263, PMID:30220460] +synonym: "ER-endosome membrane contact site" EXACT [] +is_a: GO:0044232 ! organelle membrane contact site +created_by: pg +creation_date: 2018-10-30T10:29:28Z + +[Term] +id: GO:0140285 +name: endosome fission +namespace: biological_process +def: "The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane." [PMID:25416943, PMID:30220460] +is_a: GO:0048285 ! organelle fission +created_by: pg +creation_date: 2018-10-30T10:36:33Z + +[Term] +id: GO:0140288 +name: GBAF complex +namespace: cellular_component +def: "A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM." [PMID:29374058] +is_a: GO:0070603 ! SWI/SNF superfamily-type complex +created_by: pg +creation_date: 2018-11-20T09:13:52Z + +[Term] +id: GO:0140289 +name: protein mono-ADP-ribosylation +namespace: biological_process +def: "The transfer, from NAD, of a single (mono) ADP-ribose molecule to protein amino acids." [PMID:25043379] +is_a: GO:0006471 ! protein ADP-ribosylation +created_by: pg +creation_date: 2018-11-22T13:52:54Z + +[Term] +id: GO:0140290 +name: peptidyl-serine ADP-deribosylation +namespace: biological_process +def: "The removal of ADP-ribose from ADP-ribosylserine." [PMID:28650317, PMID:29234005] +is_a: GO:0051725 ! protein de-ADP-ribosylation +created_by: pg +creation_date: 2018-11-22T14:32:30Z + +[Term] +id: GO:0140291 +name: peptidyl-glutamate ADP-deribosylation +namespace: biological_process +def: "The removal of ADP-ribose from ADP-ribosylglutamate." [PMID:23481255] +is_a: GO:0051725 ! protein de-ADP-ribosylation +created_by: pg +creation_date: 2018-11-22T14:34:24Z + +[Term] +id: GO:0140292 +name: ADP-ribosylserine hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose." [PMID:28650317, PMID:29234005] +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: pg +creation_date: 2018-11-22T14:35:39Z + +[Term] +id: GO:0140293 +name: ADP-ribosylglutamate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose." [PMID:23481255] +is_a: GO:0016799 ! hydrolase activity, hydrolyzing N-glycosyl compounds +created_by: pg +creation_date: 2018-11-22T14:36:37Z + +[Term] +id: GO:0140294 +name: NAD DNA ADP-ribosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA." [PMID:27471034, PMID:29361132, PMID:29520010] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +created_by: pg +creation_date: 2018-11-22T15:45:35Z + +[Term] +id: GO:0140295 +name: pathogen-derived receptor ligand activity +namespace: molecular_function +def: "The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity." [PMID:20601497] +comment: Note that this term is meant to annotate effectors for which the evolved activity is to act as a ligand to activate (for necrotrophs) or suppress (for biotrophs) the host immune system. It should not be used to annotate PAMPs (pathogen-associated molecular pattern molecules) or similar types of microbial proteins recognized by the host innate immune system (for example, PAMPs are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals). PAMPs activate innate immune responses, protecting the host from infection, but this is not the molecular function of PAMPs; those usually form the structure of the bacterial cell wall. +synonym: "innate receptor ligand activity" RELATED [] +is_a: GO:0048018 ! receptor ligand activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/16656 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19194 xsd:anyURI +created_by: pg +creation_date: 2018-11-26T13:30:21Z + +[Term] +id: GO:0140296 +name: general transcription initiation factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation." [GOC:txnOH-2018] +is_a: GO:0008134 ! transcription factor binding +created_by: pg +creation_date: 2018-11-28T12:48:06Z + +[Term] +id: GO:0140297 +name: DNA-binding transcription factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription." [GOC:txnOH-2018] +is_a: GO:0008134 ! transcription factor binding +created_by: pg +creation_date: 2018-11-28T12:48:20Z + +[Term] +id: GO:0140298 +name: endocytic iron import into cell +namespace: biological_process +def: "Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis." [PMID:23092063] +synonym: "iron import into cell by endocytosis" EXACT [] +is_a: GO:0006898 ! receptor-mediated endocytosis +is_a: GO:0033212 ! iron import into cell +created_by: pg +creation_date: 2018-12-10T10:31:31Z + +[Term] +id: GO:0140299 +name: small molecule sensor activity +namespace: molecular_function +def: "Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule." [PMID:26328879] +synonym: "small molecular sensor activity" EXACT [] +is_a: GO:0003674 ! molecular_function +created_by: pg +creation_date: 2018-12-10T14:30:28Z + +[Term] +id: GO:0140300 +name: serine import into mitochondrion +namespace: biological_process +def: "The process in which serine is transported from the cytosol, into the mitochondrial matrix." [PMID:30442778] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0032329 ! serine transport +is_a: GO:0043090 ! amino acid import +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: pg +creation_date: 2018-12-13T15:17:50Z + +[Term] +id: GO:0140301 +name: pollen-stigma interaction +namespace: biological_process +def: "The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae." [PMID:27899537] +is_a: GO:0009875 ! pollen-pistil interaction +created_by: pg +creation_date: 2019-02-22T13:58:21Z + +[Term] +id: GO:0140302 +name: pollen-style interaction +namespace: biological_process +def: "The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte." [PMID:27899537] +is_a: GO:0009875 ! pollen-pistil interaction +created_by: pg +creation_date: 2019-02-22T13:59:33Z + +[Term] +id: GO:0140303 +name: intramembrane lipid transporter activity +namespace: molecular_function +def: "Enables the transport of a lipid from a region of a membrane to a different region on the same membrane." [PMID:16828084] +synonym: "flippase activity" RELATED [] +is_a: GO:0005319 ! lipid transporter activity +relationship: part_of GO:0034204 ! lipid translocation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17648 xsd:anyURI +created_by: pg +creation_date: 2019-03-01T20:14:09Z + +[Term] +id: GO:0140306 +name: lipoprotein releasing activity +namespace: molecular_function +def: "The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex." [PMID:10783239, PMID:21670534] +is_a: GO:0140318 ! protein transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17058 xsd:anyURI +created_by: pg +creation_date: 2019-03-22T14:25:43Z + +[Term] +id: GO:0140311 +name: protein sequestering activity +namespace: molecular_function +def: "The selective interaction of a protein with a specific protein, thereby preventing it from interacting with other partners or inhibiting its localization to other areas of the cell." [PMID:1493333] +is_a: GO:0140313 ! molecular sequestering activity +intersection_of: GO:0140313 ! molecular sequestering activity +intersection_of: has_part GO:0005515 ! protein binding +relationship: has_part GO:0005515 ! protein binding +created_by: pg +creation_date: 2019-03-26T14:34:16Z + +[Term] +id: GO:0140312 +name: cargo adaptor activity +namespace: molecular_function +alt_id: GO:0098748 +def: "Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo, and membrane deformation machinery." [PMID:25795254] +synonym: "endocytic adaptor activity" NARROW [] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +relationship: part_of GO:0016192 ! vesicle-mediated transport +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17553 xsd:anyURI +created_by: pg +creation_date: 2019-03-26T17:01:45Z + +[Term] +id: GO:0140313 +name: molecular sequestering activity +namespace: molecular_function +def: "The selective interaction of a protein with a specific molecule, thereby preventing it from interacting with other partners or inhibiting its localization to other areas of the cell." [PMID:13130076] +is_a: GO:0003674 ! molecular_function +relationship: has_part GO:0005488 ! binding +created_by: pg +creation_date: 2019-03-28T10:00:25Z + +[Term] +id: GO:0140314 +name: calcium ion sequestering activity +namespace: molecular_function +def: "The selective interaction of a protein with a calcium ion, thereby preventing it from interacting with other partners or inhibiting its localization to other areas of the cell." [PMID:13130076] +is_a: GO:0140313 ! molecular sequestering activity +intersection_of: GO:0140313 ! molecular sequestering activity +intersection_of: has_part GO:0005509 ! calcium ion binding +relationship: has_part GO:0005509 ! calcium ion binding +created_by: pg +creation_date: 2019-03-28T10:07:18Z + +[Term] +id: GO:0140315 +name: iron ion sequestering activity +namespace: molecular_function +def: "The selective interaction of a protein with an iron ion, thereby preventing it from interacting with other partners or inhibiting its localization to other areas of the cell." [PMID:27780864] +is_a: GO:0140313 ! molecular sequestering activity +intersection_of: GO:0140313 ! molecular sequestering activity +intersection_of: has_part GO:0005506 ! iron ion binding +relationship: has_part GO:0005506 ! iron ion binding +created_by: pg +creation_date: 2019-03-28T10:10:33Z + +[Term] +id: GO:0140316 +name: obsolete vesicular transport adaptor activity +namespace: molecular_function +def: "OBSOLETE. Binding directly to sorting signals in the cytosolic tails of transmembrane cargos (or transmembrane cargo receptors serving as recognition interfaces for lumenal cargos), to concentrate them into vesicles or tubules for transport via intracellular vesicular transport or the secretory pathway." [PMID:25795254] +comment: Thi sterm was obsoleted because it represented an unnecessary grouping class. +is_obsolete: true +created_by: pg +creation_date: 2019-03-28T12:03:57Z + +[Term] +id: GO:0140317 +name: export across cell outer membrane +namespace: biological_process +def: "The directed movement of a substance across the outer membrane in cells with two membranes." [PMID:15968039] +is_a: GO:0055085 ! transmembrane transport +created_by: pg +creation_date: 2019-04-01T08:12:23Z + +[Term] +id: GO:0140318 +name: protein transporter activity +namespace: molecular_function +def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423] +comment: Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation. +synonym: "protein carrier activity" RELATED [] +synonym: "protein transport chaperone" RELATED [] +is_a: GO:0005215 ! transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17073 xsd:anyURI +created_by: pg +creation_date: 2019-04-01T10:41:38Z + +[Term] +id: GO:0140319 +name: receptor decoy activity +namespace: molecular_function +alt_id: GO:0005040 +def: "Recognizing, binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor." [Wikipedia:Decoy_receptors] +synonym: "decoy death receptor activity" NARROW [] +synonym: "decoy receptor" EXACT [] +is_a: GO:0140313 ! molecular sequestering activity +created_by: pg +creation_date: 2019-04-02T10:57:46Z + +[Term] +id: GO:0140320 +name: PAMP receptor decoy activity +namespace: molecular_function +def: "A gene product which recognizes, binds and sequesters PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response." [PMID:20724636] +synonym: "pathogen-associated molecular pattern receptor decoy activity" EXACT [] +synonym: "pattern recognition receptor decoy activity" EXACT [] +is_a: GO:0140319 ! receptor decoy activity +created_by: pg +creation_date: 2019-04-02T11:07:13Z + +[Term] +id: GO:0140321 +name: negative regulation by symbiont of host autophagy +namespace: biological_process +def: "Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pg] +is_a: GO:0010507 ! negative regulation of autophagy +is_a: GO:0075071 ! modulation by symbiont of host autophagy +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: negatively_regulates GO:0006914 ! autophagy +created_by: pg +creation_date: 2019-04-03T09:21:48Z + +[Term] +id: GO:0140323 +name: solute:anion antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(in) + solute(out) = anion(out) + solute(in)." [GOC:pg] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015297 ! antiporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +created_by: pg +creation_date: 2019-04-03T16:23:14Z + +[Term] +id: GO:0140325 +name: negative regulation of protein localization to medial cortex +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex." [PMID:30853434] +is_a: GO:0106011 ! regulation of protein localization to medial cortex +is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane +is_a: GO:1904777 ! negative regulation of protein localization to cell cortex +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0071574 ! protein localization to medial cortex +relationship: negatively_regulates GO:0071574 ! protein localization to medial cortex +created_by: pg +creation_date: 2019-04-17T11:58:27Z + +[Term] +id: GO:0140326 +name: ATPase-coupled intramembrane lipid transporter activity +namespace: molecular_function +alt_id: GO:0004012 +alt_id: GO:0008557 +def: "Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases." [PMID:16828084] +synonym: "aminophospholipid-transporting ATPase" RELATED [] +synonym: "ATPase-coupled phospholipid transporter activity" RELATED [] +synonym: "ATPase-dependent phospholipid transporter activity" RELATED [] +synonym: "phospholipid flippase activity" NARROW [] +synonym: "phospholipid translocating ATPase activity" RELATED [] +synonym: "phospholipid-translocating ATPase activity" RELATED [] +synonym: "phospholipid-transporting ATPase activity" RELATED [EC:7.6.2.1] +xref: EC:7.6.2.1 +xref: MetaCyc:3.6.3.1-RXN +xref: Reactome:R-HSA-939763 "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane" +xref: Reactome:R-HSA-947591 "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane" +is_a: GO:0140303 ! intramembrane lipid transporter activity +intersection_of: GO:0140303 ! intramembrane lipid transporter activity +intersection_of: has_part GO:0016887 ! ATPase activity +relationship: has_part GO:0016887 ! ATPase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17648 xsd:anyURI +created_by: pg +creation_date: 2019-04-29T12:42:26Z + +[Term] +id: GO:0140327 +name: flippase activity +namespace: molecular_function +def: "Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:20043909, PMID:25284293, Wikipedia:Flippase] +comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. Some authors however use the names flippases and floppases interchangeably to denote any enzyme catalyzing transbilayer lipid motion, in some cases even in the absence of ATP requirements (PMID 20043909). The direction of the translocation should be taken into account for annotation. +synonym: "flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0140326 ! ATPase-coupled intramembrane lipid transporter activity +created_by: pg +creation_date: 2019-04-29T12:51:21Z + +[Term] +id: GO:0140328 +name: floppase activity +namespace: molecular_function +def: "Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:20043909, PMID:25284293, Wikipedia:Flippase] +comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. Some authors however use the names flippases and floppases interchangeably to denote any enzyme catalyzing transbilayer lipid motion, in some cases even in the absence of ATP requirements (PMID 20043909). The direction of the translocation should be taken into account for annotation. +synonym: "floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +is_a: GO:0140326 ! ATPase-coupled intramembrane lipid transporter activity +created_by: pg +creation_date: 2019-04-29T12:58:53Z + +[Term] +id: GO:0140329 +name: lysophospholipid translocation +namespace: biological_process +def: "The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet." [PMID:15661733] +is_a: GO:0045332 ! phospholipid translocation +is_a: GO:0051977 ! lysophospholipid transport +created_by: pg +creation_date: 2019-05-03T07:26:52Z + +[Term] +id: GO:0140330 +name: xenobiotic detoxification by transmembrane export across the cell outer membrane +namespace: biological_process +def: "A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane." [PMID:11948170] +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0140317 ! export across cell outer membrane +relationship: part_of GO:0098754 ! detoxification +created_by: pg +creation_date: 2019-05-03T10:35:57Z + +[Term] +id: GO:0140331 +name: aminophospholipid translocation +namespace: biological_process +def: "The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet." [GOC:pg] +is_a: GO:0015917 ! aminophospholipid transport +is_a: GO:0045332 ! phospholipid translocation +created_by: pg +creation_date: 2019-05-10T13:46:34Z + +[Term] +id: GO:0140332 +name: lipopolysaccharide transfer activity +namespace: molecular_function +def: "Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane." [PMID:24639492] +synonym: "intermembrane lipopolysaccharide transfer activity" EXACT [] +synonym: "intermembrane lipopolysaccharide transporter activity" EXACT [] +synonym: "intermembrane LPS transporter activity" EXACT [] +synonym: "lipopolysaccharide carrier activity" EXACT [] +is_a: GO:0120013 ! lipid transfer activity +relationship: part_of GO:0015920 ! lipopolysaccharide transport +created_by: pg +creation_date: 2019-05-13T08:17:35Z + +[Term] +id: GO:0140333 +name: glycerophospholipid flippase activity +namespace: molecular_function +def: "Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:26212235] +synonym: "glycerophospholipid flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0140327 ! flippase activity +created_by: pg +creation_date: 2019-05-13T11:14:56Z + +[Term] +id: GO:0140334 +name: lipopolysaccharide localization to cell outer membrane +namespace: biological_process +def: "A process in which a lipopolysaccharide is transported to the cell outer membrane." [PMID:24639492] +synonym: "LPS localization to cell outer membrane" EXACT [] +is_a: GO:0010876 ! lipid localization +created_by: pg +creation_date: 2019-05-13T12:23:36Z + +[Term] +id: GO:0140337 +name: diacylglyceride transfer activity +namespace: molecular_function +def: "Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location." [PMID:9132017] +synonym: "diacylglyceride carrier activity" EXACT [] +is_a: GO:0120013 ! lipid transfer activity +created_by: pg +creation_date: 2019-05-16T11:28:08Z + +[Term] +id: GO:0140338 +name: sphingomyelin transfer activity +namespace: molecular_function +alt_id: GO:0010175 +def: "Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane." [PMID:9132017] +synonym: "sphingomyelin carrier activity" EXACT [] +synonym: "sphingosine transmembrane transporter activity" BROAD [] +is_a: GO:0120014 ! phospholipid transfer activity +is_a: GO:0120016 ! sphingolipid transfer activity +created_by: pg +creation_date: 2019-05-16T11:31:58Z + +[Term] +id: GO:0140339 +name: phosphatidylglycerol transfer activity +namespace: molecular_function +def: "Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location." [PMID:9132017] +synonym: "phosphatidylglycerol carrier activity" EXACT [] +is_a: GO:0120014 ! phospholipid transfer activity +created_by: pg +creation_date: 2019-05-16T11:34:45Z + +[Term] +id: GO:0140340 +name: cerebroside transfer activity +namespace: molecular_function +def: "Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location." [PMID:9132017] +synonym: "cerebroside carrier activity" EXACT [] +is_a: GO:0017089 ! glycolipid transfer activity +is_a: GO:0120017 ! ceramide transfer activity +created_by: pg +creation_date: 2019-05-16T11:37:31Z + +[Term] +id: GO:0140341 +name: phosphatidylethanolamine floppase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:10029989] +synonym: "phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaftlet)" EXACT [] +is_a: GO:0005548 ! phospholipid transporter activity +is_a: GO:0140328 ! floppase activity +created_by: pg +creation_date: 2019-05-16T11:40:45Z + +[Term] +id: GO:0140343 +name: phosphatidylserine transfer activity +namespace: molecular_function +def: "Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane." [PMID:26206935] +synonym: "intermembrane phosphatidylserine carrier activity" NARROW [] +is_a: GO:0120014 ! phospholipid transfer activity +created_by: pg +creation_date: 2019-05-16T11:46:19Z + +[Term] +id: GO:0140344 +name: triglyceride transfer activity +namespace: molecular_function +def: "Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location." [PMID:23475612] +synonym: "triglyceride carrier activity" EXACT [] +is_a: GO:0120013 ! lipid transfer activity +created_by: pg +creation_date: 2019-05-16T11:53:59Z + +[Term] +id: GO:0140345 +name: phosphatidylcholine flippase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:11870854] +synonym: "phosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0008525 ! phosphatidylcholine transporter activity +is_a: GO:0140333 ! glycerophospholipid flippase activity +created_by: pg +creation_date: 2019-05-16T13:43:47Z + +[Term] +id: GO:0140346 +name: phosphatidylserine flippase activity +namespace: molecular_function +def: "Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:11870854] +synonym: "phosphatidylserine flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0015247 ! aminophospholipid flippase activity +is_a: GO:0140333 ! glycerophospholipid flippase activity +created_by: pg +creation_date: 2019-05-16T13:44:23Z + +[Term] +id: GO:0140347 +name: N-retinylidene-phosphatidylethanolamine flippase activity +namespace: molecular_function +def: "Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:10412977] +synonym: "N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0140333 ! glycerophospholipid flippase activity +created_by: pg +creation_date: 2019-05-16T13:44:51Z + +[Term] +id: GO:0140348 +name: lysophosphatidylcholine flippase activity +namespace: molecular_function +def: "Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP." [PMID:26945070] +synonym: "lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0140333 ! glycerophospholipid flippase activity +created_by: pg +creation_date: 2019-05-16T13:45:17Z + +[Term] +id: GO:0140351 +name: glycosylceramide flippase activity +namespace: molecular_function +def: "Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar." [PMID:30530492] +synonym: "galactocerebroside flippase activity" NARROW [] +synonym: "galactosylceramide flippase activity" NARROW [] +synonym: "glucosylceramide flippase activity" NARROW [] +synonym: "glycoceramide flippase activity" EXACT [] +synonym: "glycosylceramide flippase activity (exoplasmic to cytosolic leaftlet)" EXACT [] +is_a: GO:0046624 ! sphingolipid transporter activity +is_a: GO:0140327 ! flippase activity +created_by: pg +creation_date: 2019-05-20T13:29:48Z + +[Term] +id: GO:0140352 +name: export from cell +namespace: biological_process +def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg] +synonym: "efflux" BROAD [] +is_a: GO:0006810 ! transport +is_a: GO:0009987 ! cellular process +created_by: pg +creation_date: 2019-05-22T11:20:45Z + +[Term] +id: GO:0140353 +name: lipid export from cell +namespace: biological_process +def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg] +synonym: "lipid efflux" BROAD [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0140352 ! export from cell +created_by: pg +creation_date: 2019-05-22T11:33:07Z + +[Term] +id: GO:0140354 +name: lipid import into cell +namespace: biological_process +def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] +synonym: "lipid uptake" BROAD [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0098657 ! import into cell +created_by: pg +creation_date: 2019-05-22T11:38:15Z + +[Term] +id: GO:0140355 +name: cargo receptor ligand activity +namespace: molecular_function +def: "The activity of a gene product that interacts with a cargo receptor and initiates endocytosis." [PMID:15797858] +synonym: "cargo" RELATED [] +is_a: GO:0005488 ! binding +created_by: pg +creation_date: 2019-05-27T09:56:50Z + +[Term] +id: GO:0140357 +name: heme export from vacuole to cytoplasm +namespace: biological_process +def: "The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol." [PMID:28193844] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0035351 ! heme transmembrane transport +is_a: GO:0097037 ! heme export +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17407 xsd:anyURI +created_by: pg +creation_date: 2019-05-28T07:40:48Z + +[Term] +id: GO:0140358 +name: P-type transmembrane transporter activity +namespace: molecular_function +def: "Primary transporter characterized by auto- (or self-) phosphorylation (hence P) of a key conserved aspartate residue. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane." [Wikipedia:P-type_ATPase] +synonym: "E1-E2 ATPase" EXACT [Wikipedia:P-type_ATPase] +synonym: "P-type ATPase" EXACT [Wikipedia:P-type_ATPase] +xref: TC:3.A.3 +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +created_by: pg +creation_date: 2019-06-25T19:07:46Z + +[Term] +id: GO:0140359 +name: ABC-type transmembrane transporter activity +namespace: molecular_function +def: "Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane." [PMID:26517899] +synonym: "ABC transporter" EXACT [] +synonym: "ABC-type efflux permease activity" EXACT [] +synonym: "ABC-type efflux porter activity" EXACT [] +synonym: "ABC-type uptake permease activity" EXACT [] +synonym: "ATP binding cassette transporter" EXACT [] +synonym: "ATP-binding cassette (ABC) transporter activity" EXACT [] +synonym: "ATP-binding cassette transporter" EXACT [] +xref: TC:3.A.1 +xref: Wikipedia:ATP-binding_cassette_transporter +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +created_by: pg +creation_date: 2019-06-25T19:08:14Z + +[Term] +id: GO:0140360 +name: cyclic-GMP-AMP transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other." [PMID:31126740] +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0001409 ! guanine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +created_by: pg +creation_date: 2019-07-02T14:49:32Z + +[Term] +id: GO:0140361 +name: cyclic-GMP-AMP transmembrane import across plasma membrane +namespace: biological_process +def: "The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol." [PMID:31126740] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:0070729 ! cyclic nucleotide transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1903790 ! guanine nucleotide transmembrane transport +created_by: pg +creation_date: 2019-07-02T15:49:24Z + +[Term] +id: GO:0140363 +name: TIS granule +namespace: cellular_component +def: "A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER)." [PMID:30449617, PMID:30479375, Wikipedia:TIGER_domain] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +created_by: pg +creation_date: 2019-07-25T19:20:58Z + +[Term] +id: GO:0140364 +name: GW body +namespace: cellular_component +def: "A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs." [PMID:16418578, PMID:26930655, PMID:29576456] +synonym: "GW-body" EXACT [] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +created_by: pg +creation_date: 2019-07-25T19:26:48Z + +[Term] +id: GO:0140365 +name: RNP body +namespace: cellular_component +def: "A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules." [PMID:30197298] +synonym: "BR-body" EXACT [] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +created_by: pg +creation_date: 2019-07-25T19:31:17Z + +[Term] +id: GO:0140366 +name: galectin lattice +namespace: cellular_component +def: "A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids." [PMID:19021578, PMID:26092931, PMID:28893908, PMID:30951647] +is_a: GO:0098635 ! protein complex involved in cell-cell adhesion +created_by: pg +creation_date: 2019-07-25T19:35:05Z + +[Term] +id: GO:0140367 +name: antibacterial innate immune response +namespace: biological_process +def: "An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens." [PMID:16177355, PMID:23006328] +is_a: GO:0042742 ! defense response to bacterium +is_a: GO:0045087 ! innate immune response +created_by: pg +creation_date: 2019-09-09T11:02:47Z + +[Term] +id: GO:0140368 +name: decoy receptor complex +namespace: cellular_component +def: "A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound." [GOC:bhm, PMID:30621730, PMID:9168977] +synonym: "osteoclastogenesis inhibitory factor" NARROW [] +synonym: "osteoprotegerin complex" NARROW [] +is_a: GO:0043235 ! receptor complex +created_by: pg +creation_date: 2019-09-13T16:39:24Z + +[Term] +id: GO:0140372 +name: histone H3 ubiquitination +namespace: biological_process +def: "The modification of histone H3 by the addition of one or more ubiquitin groups." [GOC:mah, PMID:31468675] +synonym: "histone H3 ubiquitylation" EXACT [] +is_a: GO:0016574 ! histone ubiquitination +created_by: pg +creation_date: 2019-10-03T15:29:54Z + +[Term] +id: GO:0140373 +name: histone H3-K14 ubiquitination +namespace: biological_process +def: "The modification of histone H3 by the addition of one or more ubiquitin groups to a lysine residue at position 14 of the histone." [GOC:mah, PMID:31468675] +synonym: "histone H3 ubiquitination at K14" EXACT [] +synonym: "histone H3-K14 ubiquitylation" EXACT [] +synonym: "histone H3K14 ubiquitination" EXACT [] +is_a: GO:0140372 ! histone H3 ubiquitination +created_by: pg +creation_date: 2019-10-03T15:31:15Z + +[Term] +id: GO:0140374 +name: antiviral innate immune response +namespace: biological_process +def: "A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens." [PMID:31006531] +is_a: GO:0045087 ! innate immune response +is_a: GO:0051607 ! defense response to virus +created_by: pg +creation_date: 2019-10-10T16:41:12Z + +[Term] +id: GO:0140375 +name: immune receptor activity +namespace: molecular_function +def: "Receiving a signal and transmitting it in a cell to initiate an immune response." [PMID:31415752, Wikipedia:Immune_receptor] +is_a: GO:0038023 ! signaling receptor activity +created_by: pg +creation_date: 2019-10-18T14:11:15Z + +[Term] +id: GO:0140376 +name: innate immune receptor activity +namespace: molecular_function +def: "Receiving a signal and transmitting it in a cell to initiate an innate immune response." [PMID:28921463, PMID:31415752] +is_a: GO:0140375 ! immune receptor activity +created_by: pg +creation_date: 2019-10-18T14:21:28Z + +[Term] +id: GO:0140380 +name: psilocybin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product." [PMID:28763571] +is_a: GO:0006568 ! tryptophan metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1902221 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process +relationship: has_part GO:0140382 ! tryptamine 4-monooxygenase activity +relationship: has_part GO:0140383 ! 4-hydroxytryptamine kinase activity +created_by: pg +creation_date: 2019-11-20T10:03:05Z + +[Term] +id: GO:0140381 +name: 4-hydroxytryptamine 4-phosphate methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin." [PMID:28763571] +synonym: "norbaeocystin methyltransferase" EXACT [] +synonym: "psilocybin synthase" EXACT [] +xref: EC:2.1.1.345 +xref: RHEA:55568 +is_a: GO:0008168 ! methyltransferase activity +created_by: pg +creation_date: 2019-11-20T10:16:28Z + +[Term] +id: GO:0140382 +name: tryptamine 4-monooxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O." [PMID:28763571] +xref: EC:1.14.99.59 +xref: RHEA:15865 +is_a: GO:0004497 ! monooxygenase activity +created_by: pg +creation_date: 2019-11-20T10:26:21Z + +[Term] +id: GO:0140383 +name: 4-hydroxytryptamine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H(+)." [PMID:28763571] +xref: EC:2.7.1.222 +xref: RHEA:55564 +is_a: GO:0016301 ! kinase activity +created_by: pg +creation_date: 2019-11-20T10:30:05Z + +[Term] +id: GO:0140384 +name: metacyclogenesis +namespace: biological_process +def: "The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania." [PMID:12152483, PMID:21514274, PMID:2659372, PMID:29091711, PMID:29409544] +is_a: GO:0044114 ! development of symbiont in host +created_by: pg +creation_date: 2019-11-20T13:25:55Z + +[Term] +id: GO:0140393 +name: norsolorinic acid ketoreductase activity +namespace: molecular_function +def: "Catalysis of the reaction: (1'S)-averantin + NADP(+) <=> norsolorinic acid + NADPH." [PMID:10584035, PMID:8368836, RHEA:35447] +xref: EC:1.1.1.349 +xref: KEGG_REACTION:R10309 +xref: MetaCyc:RXN-9480 +xref: RHEA:35447 +is_a: GO:0045703 ! ketoreductase activity +created_by: pg +creation_date: 2019-11-28T14:38:12Z + +[Term] +id: GO:0140394 +name: ATPase-coupled azole transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out)." [PMID:31501141] +synonym: "azole ABC transporter activity" EXACT [] +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +created_by: pg +creation_date: 2019-11-28T18:29:48Z + +[Term] +id: GO:0140395 +name: averantin hydroxylase activity +namespace: molecular_function +def: "Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O(2) <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H(2)O. Involved in aflatoxin biosynthesis." [EC:1.14.14.116, PMID:8368836] +xref: EC:1.14.14.116 +xref: MetaCyc:RXN-9482 +xref: RHEA:35575 +is_a: GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +relationship: part_of GO:0045122 ! aflatoxin biosynthetic process +created_by: pg +creation_date: 2019-11-29T08:48:23Z + +[Term] +id: GO:0140396 +name: 5'-hydroxyaverantin dehydrogenase activity +namespace: molecular_function +def: "Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH." [EC:1.1.1.352, PMID:14602595] +xref: EC:1.1.1.352 +xref: RHEA:35475 +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: pg +creation_date: 2019-11-29T08:56:49Z + +[Term] +id: GO:0140397 +name: versiconal hemiacetal acetate esterase activity +namespace: molecular_function +def: "Catalyzes the reactions: versiconal hemiacetal acetate + H(2)O <=> versiconal + acetate, as well as versiconol acetate + H(2)O <=> versiconol + acetate." [EC:3.1.1.94, PMID:15006741, PMID:15932995, PMID:8368837] +xref: EC:3.1.1.94 +xref: MetaCyc:RXN-9488 +xref: MetaCyc:RXN-9493 +xref: RHEA:35715 +is_a: GO:0016788 ! hydrolase activity, acting on ester bonds +created_by: pg +creation_date: 2019-11-29T10:14:17Z + +[Term] +id: GO:0140398 +name: versicolorin B desaturase activity +namespace: molecular_function +def: "Catalyzes the reaction: versicolorin B + NADPH + O(2) <=> versicolorin A + NADP(+) + 2 H(2)O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus." [PMID:15006741, PMID:8368837] +xref: KEGG_REACTION:R10479 +xref: MetaCyc:RXN-9495 +xref: RHEA:35743 +is_a: GO:0016717 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water +created_by: pg +creation_date: 2019-11-29T10:30:25Z + +[Term] +id: GO:0140399 +name: aflatoxin B synthase activity +namespace: molecular_function +def: "Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H(2)O + methanol + CO(2). Produces both aflatoxin B(1) and aflatoxin B(2)." [EC:1.14.14.117] +xref: EC:1.14.14.117 +xref: MetaCyc:RXN-9497 +xref: MetaCyc:RXN-9502 +xref: RHEA:35759 +is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen +relationship: part_of GO:0045122 ! aflatoxin biosynthetic process +created_by: pg +creation_date: 2019-11-29T11:06:07Z + +[Term] +id: GO:0140403 +name: effector-mediated suppression of host innate immune response by symbiont +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21467214, PMID:30584105] +synonym: "effector dependent suppression of host immune innate response by symbiont" EXACT [] +synonym: "effector triggered suppression of host immune innate response by symbiont" EXACT [] +synonym: "effector-dependent suppression of host immune innate response by symbiont" EXACT [] +synonym: "effector-mediated suppression of host immune innate response by symbiont" EXACT [] +synonym: "effector-mediated suppression of host innate immunity" EXACT [] +synonym: "effector-triggered suppression of host immune innate response by symbiont" EXACT [] +is_a: GO:0140404 ! effector-mediated modulation of host innate immune response by symbiont +created_by: pg +creation_date: 2019-12-05T11:34:55Z + +[Term] +id: GO:0140404 +name: effector-mediated modulation of host innate immune response by symbiont +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21467214] +synonym: "effector mediated modulation of host immune response by symbiont" EXACT [] +synonym: "effector triggered modulation of host immune response by symbiont" EXACT [] +synonym: "effector-dependent modulation of host immune response by symbiont" EXACT [] +synonym: "effector-mediated modulation of host immunity" EXACT [] +synonym: "effector-triggered modulation of host immune response by symbiont" EXACT [] +is_a: GO:0052167 ! modulation by symbiont of host innate immune response +is_a: GO:0140415 ! effector-mediated modulation of host defenses by symbiont +created_by: pg +creation_date: 2019-12-05T11:38:44Z + +[Term] +id: GO:0140405 +name: spindle pole body-led chromosome movement during mitotic interphase +namespace: biological_process +def: "A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase." [PMID:31483748] +is_a: GO:0007018 ! microtubule-based movement +is_a: GO:0051303 ! establishment of chromosome localization +relationship: happens_during GO:0051329 ! mitotic interphase +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18373 xsd:anyURI +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19149 xsd:anyURI +created_by: pg +creation_date: 2019-12-10T09:13:47Z + +[Term] +id: GO:0140406 +name: L-alanine export across the plasma membrane +namespace: biological_process +def: "The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region." [PMID:26073055, PMID:31591285] +is_a: GO:0032973 ! amino acid export across plasma membrane +is_a: GO:1904557 ! L-alanine transmembrane transport +created_by: pg +creation_date: 2019-12-11T14:13:07Z + +[Term] +id: GO:0140407 +name: L-alanine:proton antiporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out)." [PMID:26073055, PMID:31591285] +is_a: GO:0015180 ! L-alanine transmembrane transporter activity +is_a: GO:0015299 ! solute:proton antiporter activity +is_a: GO:0015491 ! cation:cation antiporter activity +created_by: pg +creation_date: 2019-12-11T14:17:48Z + +[Term] +id: GO:0140408 +name: regulation of mRNA alternative polyadenylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation." [PMID:29507755] +is_a: GO:1900363 ! regulation of mRNA polyadenylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0110104 ! mRNA alternative polyadenylation +relationship: regulates GO:0110104 ! mRNA alternative polyadenylation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15389 xsd:anyURI +created_by: pg +creation_date: 2019-12-13T12:48:14Z + +[Term] +id: GO:0140409 +name: positive regulation of mRNA alternative polyadenylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation." [PMID:29507755] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0140408 ! regulation of mRNA alternative polyadenylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0110104 ! mRNA alternative polyadenylation +relationship: positively_regulates GO:0110104 ! mRNA alternative polyadenylation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15389 xsd:anyURI +created_by: pg +creation_date: 2019-12-13T12:48:31Z + +[Term] +id: GO:0140410 +name: solute:bicarbonate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + HCO3-(out) = solute(in) + HCO3-(in)." [PMID:27166256] +is_a: GO:0015106 ! bicarbonate transmembrane transporter activity +is_a: GO:0015293 ! symporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18345 xsd:anyURI +created_by: pg +creation_date: 2020-01-07T16:58:49Z + +[Term] +id: GO:0140412 +name: zinc:bicarbonate symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in)." [PMID:27166256] +is_a: GO:0015294 ! solute:cation symporter activity +is_a: GO:0046915 ! transition metal ion transmembrane transporter activity +is_a: GO:0140410 ! solute:bicarbonate symporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18345 xsd:anyURI +created_by: pg +creation_date: 2020-01-07T18:43:02Z + +[Term] +id: GO:0140413 +name: zinc:bicarbonate:selenite symporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out)." [PMID:27166256] +is_a: GO:0015296 ! anion:cation symporter activity +is_a: GO:0140412 ! zinc:bicarbonate symporter activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18345 xsd:anyURI +created_by: pg +creation_date: 2020-01-07T18:58:12Z + +[Term] +id: GO:0140414 +name: phosphopantetheine-dependent carrier activity +namespace: molecular_function +def: "Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate." [PMID:17502372] +synonym: "carrier protein activity" EXACT [] +is_a: GO:0140104 ! molecular carrier activity +created_by: pg +creation_date: 2020-01-14T16:15:04Z + +[Term] +id: GO:0140415 +name: effector-mediated modulation of host defenses by symbiont +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:30610168] +is_a: GO:0030682 ! mitigation of host defenses by symbiont +created_by: pg +creation_date: 2020-01-20T16:46:41Z + +[Term] +id: GO:0140416 +name: DNA-binding transcription factor inhibitor activity +namespace: molecular_function +def: "An activity that stops, prevents, or reduces the activity of a DNA binding transcription factor activity." [PMID:10652346] +comment: An example is TCF23 Q7RTU1 is an example of a protein that regulates transcription factors by heterodimerising or binding to DbTFs and prevent DNA binding and their specific genomic binding site where the dbTF would have activated or repressed transcription. Also an example is NFKBIA P25963 which has a different way of regulating transcription factor activity by sequestering the dbTF (complex) in the cytoplasm. Another example is the HSP90 and HSP23 proteins that sequester steroid receptors away from the DNA. +is_a: GO:0098772 ! molecular function regulator +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18596 xsd:anyURI +created_by: pg +creation_date: 2020-01-21T14:17:39Z + +[Term] +id: GO:0140417 +name: ATP-sensitive calcium-release channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts." [PMID:22736763] +is_a: GO:0015278 ! calcium-release channel activity +created_by: pg +creation_date: 2020-01-27T09:22:04Z + +[Term] +id: GO:0140418 +name: effector-mediated modulation of host process by symbiont +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21467214] +synonym: "effector mediated modulation of host process by symbiont" EXACT [] +synonym: "effector triggered modulation of host process by symbiont" EXACT [] +synonym: "effector-dependent modulation of host process by symbiont" EXACT [] +is_a: GO:0140415 ! effector-mediated modulation of host defenses by symbiont +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18605 xsd:anyURI +created_by: pg +creation_date: 2020-01-29T21:24:42Z + +[Term] +id: GO:0140420 +name: heme import into cell +namespace: biological_process +def: "The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [PMID:28193844] +synonym: "heme assimilation" BROAD [] +is_a: GO:0015886 ! heme transport +is_a: GO:0033212 ! iron import into cell +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18671 xsd:anyURI +created_by: pg +creation_date: 2020-01-30T13:10:07Z + +[Term] +id: GO:0140421 +name: endocytic heme import into cell +namespace: biological_process +def: "The directed movement into cell of externally available heme by receptor-mediated endocytosis." [PMID:28193844] +synonym: "heme assimilation" BROAD [] +is_a: GO:0006898 ! receptor-mediated endocytosis +is_a: GO:0140420 ! heme import into cell +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18671 xsd:anyURI +created_by: pg +creation_date: 2020-01-30T13:14:02Z + +[Term] +id: GO:0140423 +name: effector-mediated suppression of pattern-triggered immunity signaling +namespace: biological_process +def: "A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants." [PMID:30584105] +synonym: "effector-mediated suppression of host pattern recognition receptor signaling" BROAD [] +synonym: "effector-mediated suppression of host PRR signaling" BROAD [] +synonym: "effector-mediated suppression of host PRR signalling" BROAD [] +synonym: "effector-mediated suppression of pattern-triggered immunity signaling" EXACT [] +synonym: "effector-mediated suppression of PTI signalling" EXACT [] +is_a: GO:0140403 ! effector-mediated suppression of host innate immune response by symbiont +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18683 xsd:anyURI +created_by: pg +creation_date: 2020-02-03T09:50:33Z + +[Term] +id: GO:0140425 +name: galactose import across plasma membrane +namespace: biological_process +def: "The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol." [PMID:23254763] +is_a: GO:0015757 ! galactose transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18788 xsd:anyURI +created_by: pg +creation_date: 2020-02-10T08:46:09Z + +[Term] +id: GO:0140426 +name: PAMP-triggered immunity signalling pathway +namespace: biological_process +def: "Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species." [PMID:25744358] +synonym: "MAMP-triggered immunity signalling" EXACT [] +synonym: "pathogen-associated molecular pattern signalling" EXACT [] +synonym: "PTI signalling" EXACT [] +is_a: GO:0002221 ! pattern recognition receptor signaling pathway +is_a: GO:0002758 ! innate immune response-activating signal transduction +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18588 xsd:anyURI +created_by: pg +creation_date: 2020-02-11T11:08:57Z + +[Term] +id: GO:0140429 +name: positive regulation of mitotic sister chromatid biorientation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed." [PMID:20739936] +is_a: GO:1902425 ! positive regulation of attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1990758 ! mitotic sister chromatid biorientation +relationship: positively_regulates GO:1990758 ! mitotic sister chromatid biorientation +created_by: pg +creation_date: 2020-02-19T05:16:40Z + +[Term] +id: GO:0140430 +name: positive regulation of chromosome passenger complex localization to kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore." [PMID:20739936] +is_a: GO:1905342 ! positive regulation of protein localization to kinetochore +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072356 ! chromosome passenger complex localization to kinetochore +relationship: positively_regulates GO:0072356 ! chromosome passenger complex localization to kinetochore +created_by: pg +creation_date: 2020-02-19T05:19:45Z + +[Term] +id: GO:0140431 +name: DNA-(abasic site) binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base." [PMID:23245849] +synonym: "DNA AP site binding" EXACT [] +synonym: "DNA-(apurinic site) binding" NARROW [] +synonym: "DNA-(apurinic site/apyrimidinic site) binding" EXACT [] +synonym: "DNA-(apyrimidinic site) binding" NARROW [] +is_a: GO:0003684 ! damaged DNA binding +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18878 xsd:anyURI +created_by: pg +creation_date: 2020-02-19T05:30:09Z + +[Term] +id: GO:0140432 +name: 5'-hydroxyl dinucleotide hydrolase +namespace: molecular_function +def: "Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA." [PMID:31777937] +is_a: GO:0004540 ! ribonuclease activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18881 xsd:anyURI +created_by: pg +creation_date: 2020-02-19T05:50:35Z + +[Term] +id: GO:0140433 +name: regulation of protein localization to meiotic spindle pole body +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body." [PMID:22438582] +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:0090224 ! regulation of spindle organization +is_a: GO:1902363 ! regulation of protein localization to spindle pole body +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1902441 ! protein localization to meiotic spindle pole body +relationship: regulates GO:1902441 ! protein localization to meiotic spindle pole body +created_by: pg +creation_date: 2020-02-24T13:26:53Z + +[Term] +id: GO:0140434 +name: positive regulation of protein localization to meiotic spindle pole body +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body." [PMID:22438582] +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:0140433 ! regulation of protein localization to meiotic spindle pole body +is_a: GO:1902365 ! positive regulation of protein localization to spindle pole body +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1902441 ! protein localization to meiotic spindle pole body +relationship: positively_regulates GO:1902441 ! protein localization to meiotic spindle pole body +created_by: pg +creation_date: 2020-02-24T13:27:01Z + +[Term] +id: GO:0140435 +name: negative regulation of protein localization to meiotic spindle pole body +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body." [PMID:22438582] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:0140433 ! regulation of protein localization to meiotic spindle pole body +is_a: GO:1902364 ! negative regulation of protein localization to spindle pole body +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1902441 ! protein localization to meiotic spindle pole body +relationship: negatively_regulates GO:1902441 ! protein localization to meiotic spindle pole body +created_by: pg +creation_date: 2020-02-24T13:27:15Z + +[Term] +id: GO:0140438 +name: protein stearoylation +namespace: biological_process +def: "The covalent attachment of a stearoyl group to an amino acid in a protein." [PMID:26214738] +is_a: GO:0006497 ! protein lipidation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18882 xsd:anyURI +created_by: pg +creation_date: 2020-03-11T07:54:48Z + +[Term] +id: GO:0140439 +name: protein-cysteine S-stearoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein]." [PMID:12681491, PMID:22247542, PMID:22968831, RHEA:59740] +xref: RHEA:59740 +is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18882 xsd:anyURI +created_by: pg +creation_date: 2020-03-11T09:55:48Z + +[Term] +id: GO:0140440 +name: protein-cysteine S-oleoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein]." [PMID:22247542, RHEA:59744] +xref: RHEA:59744 +is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18882 xsd:anyURI +created_by: pg +creation_date: 2020-03-11T09:56:11Z + +[Term] +id: GO:0140441 +name: protein-cysteine S-arachidonoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein]." [PMID:12681491, PMID:22247542, PMID:22968831, RHEA:59748] +xref: RHEA:59748 +is_a: GO:0019707 ! protein-cysteine S-acyltransferase activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18882 xsd:anyURI +created_by: pg +creation_date: 2020-03-11T09:56:24Z + +[Term] +id: GO:0140442 +name: peroxide sensor activity +namespace: molecular_function +def: "Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule." [PMID:20919928] +is_a: GO:0140299 ! small molecule sensor activity +relationship: part_of GO:0042542 ! response to hydrogen peroxide +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19126 xsd:anyURI +created_by: pg +creation_date: 2020-03-24T09:09:43Z + +[Term] +id: GO:0140443 +name: mitochondrion-plasma membrane adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion." [PMID:31582398] +synonym: "mitochondrion plasma membrane adaptor activity" EXACT [] +synonym: "plasma membrane-mitochondrion adaptor activity" EXACT [] +is_a: GO:0043495 ! protein-membrane adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/pull/19140 xsd:anyURI +created_by: pg +creation_date: 2020-03-24T13:11:20Z + +[Term] +id: GO:0140444 +name: cytoskeleton-nuclear membrane anchor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the plasma membrane." [PMID:16237665] +synonym: "cytoskeletal protein-nuclear membrane adaptor activity" EXACT [] +synonym: "cytoskeletal protein-nuclear membrane anchor activity" EXACT [] +synonym: "cytoskeleton nuclear membrane anchor activity" EXACT [] +synonym: "nuclear membrane-cytoskeleton anchor activity" EXACT [] +is_a: GO:0043495 ! protein-membrane adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18283 xsd:anyURI +created_by: pg +creation_date: 2020-03-24T14:57:59Z + +[Term] +id: GO:0140445 +name: chromosome, telomeric repeat region +namespace: cellular_component +def: "A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop." [PMID:11352055, PMID:30208292] +is_a: GO:0000781 ! chromosome, telomeric region +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19086 xsd:anyURI +created_by: pg +creation_date: 2020-03-27T13:29:16Z + +[Term] +id: GO:0140446 +name: fumigermin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus." [PMID:32083553] +synonym: "fumigermin anabolism" EXACT [] +synonym: "fumigermin biosynthesis" EXACT [] +synonym: "fumigermin formation" EXACT [] +synonym: "fumigermin synthesis" EXACT [] +xref: CHEBI:147341 +is_a: GO:0044550 ! secondary metabolite biosynthetic process +created_by: pg +creation_date: 2020-03-31T12:02:29Z + +[Term] +id: GO:0140447 +name: cytokine precursor processing +namespace: biological_process +def: "The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine." [PMID:29247995] +is_a: GO:0140448 ! signaling receptor ligand precursor processing +relationship: part_of GO:0001816 ! cytokine production +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19216 xsd:anyURI +created_by: pg +creation_date: 2020-04-03T12:49:29Z + +[Term] +id: GO:0140448 +name: signaling receptor ligand precursor processing +namespace: biological_process +alt_id: GO:0035638 +def: "The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand." [PMID:29247995] +synonym: "ligand maturation" NARROW [GOC:bf] +synonym: "signal maturation" RELATED [] +is_a: GO:0009987 ! cellular process +is_a: GO:0016485 ! protein processing +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19216 xsd:anyURI +created_by: pg +creation_date: 2020-04-03T13:30:04Z + +[Term] +id: GO:0140449 +name: centromere-nuclear envelope anchor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location." [PMID:31635174] +synonym: "centromere nuclear envelope anchor activity" EXACT [] +synonym: "centromere-inner nuclear envelope anchor activity" EXACT [] +synonym: "chromosome, centromeric region-nuclear envelope anchor activity" EXACT [] +synonym: "nuclear envelope-centromere anchor activity" EXACT [] +is_a: GO:0043495 ! protein-membrane adaptor activity +relationship: part_of GO:0072766 ! centromere clustering at the mitotic interphase nuclear envelope +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19227 xsd:anyURI +created_by: pg +creation_date: 2020-04-07T06:27:08Z + +[Term] +id: GO:0140450 +name: protein targeting to Golgi apparatus +namespace: biological_process +def: "The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation)." [PMID:18817523] +is_a: GO:0006605 ! protein targeting +is_a: GO:0034067 ! protein localization to Golgi apparatus +is_a: GO:0072594 ! establishment of protein localization to organelle +created_by: pg +creation_date: 2020-04-08T13:10:10Z + +[Term] +id: GO:0140451 +name: counting factor complex +namespace: cellular_component +def: "A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum." [PMID:10444594, PMID:12117815, PMID:12912898, PMID:16963635, PMID:18426773] +is_a: GO:0032991 ! protein-containing complex +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19220 xsd:anyURI +created_by: pg +creation_date: 2020-04-15T08:52:26Z + +[Term] +id: GO:0140453 +name: protein aggregate center +namespace: cellular_component +def: "Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773] +synonym: "PAC" BROAD [] +synonym: "protein aggregate centre" EXACT [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19172 xsd:anyURI +created_by: pg +creation_date: 2020-04-20T15:21:55Z + +[Term] +id: GO:0140454 +name: protein aggregate center assembly +namespace: biological_process +def: "The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773] +synonym: "PAC assembly" BROAD [] +synonym: "protein aggregate center formation" EXACT [] +synonym: "protein aggregate centre assembly" EXACT [] +is_a: GO:0022607 ! cellular component assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19172 xsd:anyURI +created_by: pg +creation_date: 2020-04-20T15:43:52Z + +[Term] +id: GO:0140455 +name: cytoplasm protein quality control +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding." [PMID:32075773] +is_a: GO:0006515 ! protein quality control for misfolded or incompletely synthesized proteins +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19172 xsd:anyURI +created_by: pg +creation_date: 2020-04-20T15:46:20Z + +[Term] +id: GO:0140456 +name: meiotic spindle pole body duplication +namespace: biological_process +def: "The release of duplicated meiotic spindle pole bodies (SPBs)." [PMID:31532702] +synonym: "initial spindle pole body separation involved in meiosis I" EXACT [] +is_a: GO:0000073 ! initial mitotic spindle pole body separation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17971 xsd:anyURI +created_by: pg +creation_date: 2020-04-22T19:07:22Z + +[Term] +id: GO:0140457 +name: protein demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from a protein." [PMID:24498420] +is_a: GO:0032451 ! demethylase activity +is_a: GO:0140096 ! catalytic activity, acting on a protein +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19325 xsd:anyURI +created_by: pg +creation_date: 2020-04-23T07:39:14Z + +[Term] +id: GO:0140458 +name: pre-transcriptional gene silencing by RNA +namespace: biological_process +def: "Any gene inactivation (silencing) process mediated by small RNA molecules that occur before the trancription begins." [PMID:21420348] +is_a: GO:0031047 ! gene silencing by RNA +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19328 xsd:anyURI +created_by: pg +creation_date: 2020-04-24T07:19:09Z + +[Term] +id: GO:0140459 +name: response to Gram-positive bacterium +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium." [PMID:23664307] +is_a: GO:0009617 ! response to bacterium +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19278 xsd:anyURI +created_by: pg +creation_date: 2020-04-30T07:33:34Z + +[Term] +id: GO:0140460 +name: response to Gram-negative bacterium +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium." [PMID:23664307] +is_a: GO:0009617 ! response to bacterium +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19278 xsd:anyURI +created_by: pg +creation_date: 2020-04-30T07:34:38Z + +[Term] +id: GO:0150001 +name: primary dendrite +namespace: cellular_component +def: "A dendrite emerging from the cell body (the soma) of a neuron." [GOC:aruk, GOC:bc] +is_a: GO:0030425 ! dendrite + +[Term] +id: GO:0150002 +name: distal dendrite +namespace: cellular_component +def: "The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma)." [GOC:aruk, GOC:bc, PMID:20629984] +is_a: GO:0030425 ! dendrite + +[Term] +id: GO:0150003 +name: regulation of spontaneous synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission." [GOC:aruk, GOC:bc, PMID:15457210] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098814 ! spontaneous synaptic transmission +relationship: regulates GO:0098814 ! spontaneous synaptic transmission + +[Term] +id: GO:0150004 +name: dendritic spine origin +namespace: cellular_component +def: "The part of the dendritic spine neck where the spine arises from the dendritic shaft." [GOC:aruk, GOC:bc, PMID:9030614] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0044326 ! dendritic spine neck + +[Term] +id: GO:0150005 +name: enzyme activator complex +namespace: cellular_component +def: "A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active." [GOC:bhm, PMID:16244137, PMID:28710280] +xref: IntAct:EBI-16417801 +is_a: GO:0032991 ! protein-containing complex + +[Term] +id: GO:0150006 +name: urease activator complex +namespace: cellular_component +def: "A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function." [GOC:bhm, PMID:16244137, PMID:28710280] +xref: IntAct:EBI-16417801 +is_a: GO:0150005 ! enzyme activator complex + +[Term] +id: GO:0150007 +name: clathrin-dependent synaptic vesicle endocytosis +namespace: biological_process +def: "Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds." [GOC:aruk, GOC:bc, GOC:ha, PMID:16982422, PMID:18579735, PMID:18579748, PMID:26430111, PMID:27252645, PMID:28391090, PMID:4348786] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0048488 ! synaptic vesicle endocytosis +is_a: GO:0072583 ! clathrin-dependent endocytosis +relationship: part_of GO:0036466 ! synaptic vesicle recycling via endosome +created_by: bc +creation_date: 2017-12-01T10:11:35Z + +[Term] +id: GO:0150008 +name: bulk synaptic vesicle endocytosis +namespace: biological_process +def: "Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse." [GOC:aruk, GOC:bc, GOC:ha, PMID:18250322, PMID:18579735, PMID:19266323, PMID:26430111, PMID:28391090] +synonym: "activity-dependent bulk endocytosis" EXACT [] +synonym: "activity-dependent bulk synaptic vesicle endocytosis" EXACT [] +synonym: "ADBE" EXACT [] +synonym: "bulk endocytosis" EXACT [] +is_a: GO:0048488 ! synaptic vesicle endocytosis +created_by: bc +creation_date: 2017-12-01T10:20:18Z + +[Term] +id: GO:0150011 +name: regulation of neuron projection arborization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches." [GOC:aruk, GOC:bc, PMID:17114044] +synonym: "regulation of neurite arborization" EXACT [] +synonym: "regulation of neurite branching" EXACT [] +synonym: "regulation of neuron projection branching" EXACT [] +is_a: GO:0010975 ! regulation of neuron projection development +is_a: GO:0022604 ! regulation of cell morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0140058 ! neuron projection arborization +relationship: regulates GO:0140058 ! neuron projection arborization +created_by: bc +creation_date: 2017-12-13T16:32:34Z + +[Term] +id: GO:0150012 +name: positive regulation of neuron projection arborization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches." [GOC:aruk, GOC:bc, PMID:17114044] +synonym: "positive regulation of neurite arborization" EXACT [] +synonym: "positive regulation of neurite branching" EXACT [] +synonym: "positive regulation of neuron projection branching" EXACT [] +is_a: GO:0010976 ! positive regulation of neuron projection development +is_a: GO:0150011 ! regulation of neuron projection arborization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0140058 ! neuron projection arborization +relationship: positively_regulates GO:0140058 ! neuron projection arborization +created_by: bc +creation_date: 2017-12-13T16:46:57Z + +[Term] +id: GO:0150013 +name: negative regulation of neuron projection arborization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches." [GOC:aruk, GOC:bc, PMID:17114044] +synonym: "negative regulation of neurite arborization" EXACT [] +synonym: "negative regulation of neurite branching" EXACT [] +synonym: "negative regulation of neuron projection branching" EXACT [] +is_a: GO:0010977 ! negative regulation of neuron projection development +is_a: GO:0150011 ! regulation of neuron projection arborization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0140058 ! neuron projection arborization +relationship: negatively_regulates GO:0140058 ! neuron projection arborization +created_by: bc +creation_date: 2017-12-13T16:50:53Z + +[Term] +id: GO:0150014 +name: apical distal dendrite +namespace: cellular_component +def: "Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma)." [GO:bc, GOC:aruk, PMID:1720142, PMID:20629984, PMID:9214543] +is_a: GO:0097440 ! apical dendrite +is_a: GO:0150002 ! distal dendrite +created_by: bc +creation_date: 2017-12-21T12:03:28Z + +[Term] +id: GO:0150015 +name: apical proximal dendrite +namespace: cellular_component +def: "The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma)." [GOC:aruk, GOC:bc, PMID:16899232, PMID:1720142, PMID:9214543] +is_a: GO:0097440 ! apical dendrite +is_a: GO:1990635 ! proximal dendrite +created_by: bc +creation_date: 2017-12-21T12:09:26Z + +[Term] +id: GO:0150016 +name: basal distal dendrite +namespace: cellular_component +def: "Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma)." [GOC:aruk, GOC:bc, PMID:17046728, PMID:1720142, PMID:20629984, PMID:22683681, PMID:9214543] +is_a: GO:0097441 ! basal dendrite +is_a: GO:0150002 ! distal dendrite +created_by: bc +creation_date: 2017-12-21T12:11:47Z + +[Term] +id: GO:0150017 +name: basal proximal dendrite +namespace: cellular_component +def: "Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma)." [GOC:aruk, GOC:bc, PMID:16899232, PMID:17046728, PMID:1720142, PMID:22683681, PMID:9214543] +is_a: GO:0097441 ! basal dendrite +is_a: GO:1990635 ! proximal dendrite +created_by: bc +creation_date: 2017-12-21T12:17:00Z + +[Term] +id: GO:0150018 +name: basal dendrite development +namespace: biological_process +def: "The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0016358 ! dendrite development +created_by: bc +creation_date: 2017-12-22T11:09:53Z + +[Term] +id: GO:0150019 +name: basal dendrite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of a basal dendrite are generated and organized." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0048813 ! dendrite morphogenesis +relationship: part_of GO:0150018 ! basal dendrite development +created_by: bc +creation_date: 2017-12-22T11:26:07Z + +[Term] +id: GO:0150020 +name: basal dendrite arborization +namespace: biological_process +def: "The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0140059 ! dendrite arborization +is_a: GO:0150019 ! basal dendrite morphogenesis +created_by: bc +creation_date: 2017-12-22T11:32:31Z + +[Term] +id: GO:0150021 +name: apical dendrite morphogenesis +namespace: biological_process +def: "The process in which the anatomical structures of an apical dendrite are generated and organized." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0048813 ! dendrite morphogenesis +relationship: part_of GO:0150022 ! apical dendrite development +created_by: bc +creation_date: 2017-12-22T11:50:00Z + +[Term] +id: GO:0150022 +name: apical dendrite development +namespace: biological_process +def: "The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0016358 ! dendrite development +created_by: bc +creation_date: 2017-12-22T11:52:40Z + +[Term] +id: GO:0150023 +name: apical dendrite arborization +namespace: biological_process +def: "The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches." [GOC:aruk, GOC:bc, PMID:22683681] +is_a: GO:0140059 ! dendrite arborization +is_a: GO:0150021 ! apical dendrite morphogenesis +created_by: bc +creation_date: 2017-12-22T11:56:05Z + +[Term] +id: GO:0150024 +name: oxidised low-density lipoprotein particle clearance +namespace: biological_process +def: "The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded." [GOC:aruk, GOC:bc, PMID:27607416] +synonym: "ox-LDL particle clearance" EXACT [] +synonym: "oxidised LDL particle clearance" EXACT [] +synonym: "oxidized LDL particle clearance" EXACT [] +synonym: "oxidized low-density lipoprotein particle clearance" EXACT [] +synonym: "oxLDL particle clearance" EXACT [] +is_a: GO:0034381 ! plasma lipoprotein particle clearance +created_by: bc +creation_date: 2018-02-05T16:14:05Z + +[Term] +id: GO:0150025 +name: oxidised low-density lipoprotein particle receptor activity +namespace: molecular_function +def: "Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis." [GOC:aruk, GOC:bc, PMID:27607416] +synonym: "ox-LDL particle receptor activity" EXACT [] +synonym: "ox-LDL receptor activity" RELATED [] +synonym: "oxidised LDL particle receptor activity" EXACT [] +synonym: "oxidised LDL receptor activity" RELATED [] +synonym: "oxidised low-density lipoprotein receptor activity" RELATED [] +synonym: "oxidized LDL particle receptor activity" EXACT [] +synonym: "oxidized LDL receptor activity" RELATED [] +synonym: "oxidized low-density lipoprotein particle receptor activity" EXACT [] +synonym: "oxidized low-density lipoprotein receptor activity" RELATED [] +synonym: "oxLDL particle receptor activity" EXACT [] +synonym: "oxLDL receptor activity" RELATED [] +is_a: GO:0030228 ! lipoprotein particle receptor activity +created_by: bc +creation_date: 2018-02-06T14:17:33Z + +[Term] +id: GO:0150031 +name: regulation of protein localization to lysosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to lysosome." [GOC:aruk, GOC:bc, PMID:24305806] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0061462 ! protein localization to lysosome +relationship: regulates GO:0061462 ! protein localization to lysosome +created_by: bc +creation_date: 2018-02-06T17:07:03Z + +[Term] +id: GO:0150032 +name: positive regulation of protein localization to lysosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to lysosome." [GOC:aruk, GOC:bc] +is_a: GO:0150031 ! regulation of protein localization to lysosome +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0061462 ! protein localization to lysosome +relationship: positively_regulates GO:0061462 ! protein localization to lysosome +created_by: bc +creation_date: 2018-02-06T17:11:02Z + +[Term] +id: GO:0150033 +name: negative regulation of protein localization to lysosome +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome." [GOC:aruk, GOC:bc, PMID:24305806] +is_a: GO:0150031 ! regulation of protein localization to lysosome +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0061462 ! protein localization to lysosome +relationship: negatively_regulates GO:0061462 ! protein localization to lysosome +created_by: bc +creation_date: 2018-02-06T17:14:16Z + +[Term] +id: GO:0150034 +name: distal axon +namespace: cellular_component +def: "That part of an axon close to and including the growth cone or the axon terminus." [GOC:aruk, GOC:bc, PMID:17202468] +synonym: "distal part of axon" EXACT [] +synonym: "distal part of the axon" EXACT [PMID:17202468] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +created_by: bc +creation_date: 2018-02-19T15:04:24Z + +[Term] +id: GO:0150035 +name: regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission." [GOC:aruk, GOC:bc, PMID:19448629] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099183 ! trans-synaptic signaling by BDNF, modulating synaptic transmission +relationship: regulates GO:0099183 ! trans-synaptic signaling by BDNF, modulating synaptic transmission +created_by: bc +creation_date: 2018-04-17T13:56:34Z + +[Term] +id: GO:0150036 +name: regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission." [GOC:aruk, GOC:bc, PMID:27296803] +comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. +subset: goslim_synapse +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099553 ! trans-synaptic signaling by endocannabinoid, modulating synaptic transmission +relationship: regulates GO:0099553 ! trans-synaptic signaling by endocannabinoid, modulating synaptic transmission +created_by: bc +creation_date: 2018-04-18T09:54:49Z + +[Term] +id: GO:0150037 +name: regulation of calcium-dependent activation of synaptic vesicle fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion." [GOC:aruk, GOC:bc, PMID:27052163] +subset: goslim_synapse +is_a: GO:0031630 ! regulation of synaptic vesicle fusion to presynaptic active zone membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099502 ! calcium-dependent activation of synaptic vesicle fusion +relationship: regulates GO:0099502 ! calcium-dependent activation of synaptic vesicle fusion +created_by: bc +creation_date: 2018-04-18T12:47:38Z + +[Term] +id: GO:0150038 +name: postsynaptic dense core vesicle exocytosis +namespace: biological_process +def: "The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels." [GOC:aruk, GOC:bc, PMID:19448629] +subset: goslim_synapse +is_a: GO:0051649 ! establishment of localization in cell +is_a: GO:0099003 ! vesicle-mediated transport in synapse +is_a: GO:0099011 ! neuronal dense core vesicle exocytosis +intersection_of: GO:0099011 ! neuronal dense core vesicle exocytosis +intersection_of: occurs_in GO:0098794 ! postsynapse +relationship: occurs_in GO:0098794 ! postsynapse +created_by: bc +creation_date: 2018-04-18T14:32:16Z + +[Term] +id: GO:0150043 +name: structural constituent of synapse-associated extracellular matrix +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft." [GOC:aruk, GOC:bc, PMID:17189701] +subset: goslim_synapse +synonym: "extra-synaptic extracellular matrix structural constituent" EXACT [] +synonym: "structural constituent of extra-synaptic extracellular matrix" EXACT [] +synonym: "synapse-associated extracellular matrix structural constituent" EXACT [] +is_a: GO:0005201 ! extracellular matrix structural constituent +intersection_of: GO:0005201 ! extracellular matrix structural constituent +intersection_of: occurs_in GO:0099535 ! synapse-associated extracellular matrix +relationship: occurs_in GO:0099535 ! synapse-associated extracellular matrix +created_by: bc +creation_date: 2018-04-19T13:42:40Z + +[Term] +id: GO:0150044 +name: regulation of postsynaptic dense core vesicle exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis." [GOC:aruk, GOC:bc, PMID:19448629] +subset: goslim_synapse +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150038 ! postsynaptic dense core vesicle exocytosis +relationship: regulates GO:0150038 ! postsynaptic dense core vesicle exocytosis +created_by: bc +creation_date: 2018-04-20T13:34:32Z + +[Term] +id: GO:0150045 +name: regulation of synaptic signaling by nitric oxide +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide." [GOC:aruk, GOC:bc, PMID:26311509] +subset: goslim_synapse +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099163 ! synaptic signaling by nitric oxide +relationship: regulates GO:0099163 ! synaptic signaling by nitric oxide +created_by: bc +creation_date: 2018-04-23T09:42:25Z + +[Term] +id: GO:0150047 +name: G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential +namespace: molecular_function +def: "G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential." [GOC:aruk, GOC:bc, PMID:11498050] +subset: goslim_synapse +synonym: "G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential" EXACT [] +is_a: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +intersection_of: GO:0099528 ! G protein-coupled neurotransmitter receptor activity +intersection_of: part_of GO:0099505 ! regulation of presynaptic membrane potential +relationship: occurs_in GO:0042734 ! presynaptic membrane +relationship: part_of GO:0099505 ! regulation of presynaptic membrane potential +created_by: bc +creation_date: 2018-04-23T10:51:20Z + +[Term] +id: GO:0150048 +name: cerebellar granule cell to Purkinje cell synapse +namespace: cellular_component +def: "A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum." [GOC:aruk, GOC:bc, PMID:12427822] +subset: goslim_synapse +synonym: "cerebellar parallel fiber to Purkinje cell synapse" EXACT [] +is_a: GO:0098985 ! asymmetric, glutamatergic, excitatory synapse +created_by: bc +creation_date: 2018-04-23T14:44:40Z + +[Term] +id: GO:0150050 +name: postsynaptic septin cytoskeleton +namespace: cellular_component +def: "The portion of the septin cytoskeleton contained within the postsynapse." [GOC:aruk, GOC:bc, PMID:28065648] +subset: goslim_synapse +is_a: GO:0032156 ! septin cytoskeleton +is_a: GO:0099571 ! postsynaptic cytoskeleton +created_by: bc +creation_date: 2018-04-26T14:45:52Z + +[Term] +id: GO:0150051 +name: postsynaptic Golgi apparatus +namespace: cellular_component +def: "The network of the Golgi apparatus structures located within the postsynapse." [GOC:aruk, GOC:bc, PMID:23838184] +subset: goslim_synapse +synonym: "Golgi outpost" RELATED [GOC:aruk, GOC:bc, PMID:21215635] +is_a: GO:0005794 ! Golgi apparatus +relationship: part_of GO:0098794 ! postsynapse +created_by: bc +creation_date: 2018-05-08T15:42:56Z + +[Term] +id: GO:0150052 +name: regulation of postsynapse assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854] +subset: goslim_synapse +is_a: GO:0051963 ! regulation of synapse assembly +is_a: GO:0099175 ! regulation of postsynapse organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0099068 ! postsynapse assembly +relationship: regulates GO:0099068 ! postsynapse assembly +created_by: bc +creation_date: 2018-05-08T16:38:55Z + +[Term] +id: GO:0150053 +name: cerebellar climbing fiber to Purkinje cell synapse +namespace: cellular_component +def: "A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata." [GOC:aruk, GOC:bc, PMID:19597563, PMID:23811844, PMID:5044254] +subset: goslim_synapse +synonym: "cerebellar climbing fibre to Purkinje cell synapse" EXACT [] +is_a: GO:0098985 ! asymmetric, glutamatergic, excitatory synapse +created_by: bc +creation_date: 2018-05-09T09:57:20Z + +[Term] +id: GO:0150054 +name: regulation of postsynaptic neurotransmitter receptor diffusion trapping +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping." [GOC:aruk, GOC:bc, PMID:20935643] +subset: goslim_synapse +is_a: GO:0098696 ! regulation of neurotransmitter receptor localization to postsynaptic specialization membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0098970 ! postsynaptic neurotransmitter receptor diffusion trapping +relationship: regulates GO:0098970 ! postsynaptic neurotransmitter receptor diffusion trapping +created_by: bc +creation_date: 2018-05-10T14:26:59Z + +[Term] +id: GO:0150056 +name: amylin receptor complex 1 +namespace: cellular_component +def: "A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM)." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY1 complex" EXACT [] +is_a: GO:1903440 ! amylin receptor complex +created_by: bc +creation_date: 2018-06-21T10:47:10Z + +[Term] +id: GO:0150057 +name: amylin receptor complex 2 +namespace: cellular_component +def: "A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM)." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY2 complex" EXACT [] +is_a: GO:1903440 ! amylin receptor complex +created_by: bc +creation_date: 2018-06-21T10:51:35Z + +[Term] +id: GO:0150058 +name: amylin receptor complex 3 +namespace: cellular_component +def: "A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signalling pathways." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY3 complex" EXACT [] +is_a: GO:1903440 ! amylin receptor complex +created_by: bc +creation_date: 2018-06-21T10:54:00Z + +[Term] +id: GO:0150059 +name: amylin receptor 1 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM)." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY1 signaling pathway" EXACT [] +is_a: GO:0097647 ! amylin receptor signaling pathway +created_by: bc +creation_date: 2018-06-21T10:58:02Z + +[Term] +id: GO:0150060 +name: amylin receptor 2 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM)." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY2 signaling pathway" EXACT [] +is_a: GO:0097647 ! amylin receptor signaling pathway +created_by: bc +creation_date: 2018-06-21T11:00:22Z + +[Term] +id: GO:0150061 +name: amylin receptor 3 signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos." [GOC:aruk, GOC:bc, PMID:22500019] +synonym: "AMY3 signaling pathway" EXACT [] +is_a: GO:0097647 ! amylin receptor signaling pathway +created_by: bc +creation_date: 2018-06-21T11:02:09Z + +[Term] +id: GO:0150062 +name: complement-mediated synapse pruning +namespace: biological_process +def: "Synaptic pruning mediated by complement system signalling." [GOC:aruk, GOC:bc, PMID:18083105, PMID:22632727, PMID:29844190] +synonym: "complement-dependent synapse pruning" EXACT [] +synonym: "synapse clearance" BROAD [] +synonym: "synapse disassembly" BROAD [] +synonym: "synapse elimination" BROAD [] +synonym: "synapse removal" BROAD [] +is_a: GO:0098883 ! synapse pruning +created_by: bc +creation_date: 2018-07-16T17:44:59Z + +[Term] +id: GO:0150063 +name: visual system development +namespace: biological_process +def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727] +synonym: "optic pathway development" RELATED [] +synonym: "visual pathway development" RELATED [] +is_a: GO:0048880 ! sensory system development +created_by: bc +creation_date: 2018-07-23T10:31:58Z + +[Term] +id: GO:0150064 +name: vertebrate eye-specific patterning +namespace: biological_process +def: "Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus." [GOC:aruk, GOC:bc, PMID:16025107, PMID:22632727, PMID:29322522] +synonym: "binocular vision development" RELATED [] +synonym: "eye-specific patterning" BROAD [] +synonym: "eye-specific segregation" BROAD [] +synonym: "vertebrate eye-specific segregation" EXACT [] +is_a: GO:0003002 ! regionalization +relationship: part_of GO:0007417 ! central nervous system development +relationship: part_of GO:0150063 ! visual system development +created_by: bc +creation_date: 2018-07-23T10:39:44Z + +[Term] +id: GO:0150065 +name: regulation of deacetylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of deacetylase activity." [GOC:aruk, GOC:bc, PMID:19457097] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0019213 ! deacetylase activity +relationship: regulates GO:0019213 ! deacetylase activity +created_by: bc +creation_date: 2018-07-23T12:24:28Z + +[Term] +id: GO:0150066 +name: negative regulation of deacetylase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity." [GOC:aruk, GOC:bc, PMID:19457097] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0150065 ! regulation of deacetylase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0019213 ! deacetylase activity +relationship: negatively_regulates GO:0019213 ! deacetylase activity +created_by: bc +creation_date: 2018-07-23T12:37:57Z + +[Term] +id: GO:0150067 +name: regulation of tubulin deacetylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tubulin deacetylase activity." [GOC:aruk, GOC:bc, PMID:19457097] +is_a: GO:0090043 ! regulation of tubulin deacetylation +is_a: GO:0150065 ! regulation of deacetylase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0042903 ! tubulin deacetylase activity +relationship: regulates GO:0042903 ! tubulin deacetylase activity +created_by: bc +creation_date: 2018-07-24T10:29:49Z + +[Term] +id: GO:0150068 +name: positive regulation of tubulin deacetylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity." [GOC:aruk, GOC:bc] +is_a: GO:0090044 ! positive regulation of tubulin deacetylation +is_a: GO:0090045 ! positive regulation of deacetylase activity +is_a: GO:0150067 ! regulation of tubulin deacetylase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0042903 ! tubulin deacetylase activity +relationship: positively_regulates GO:0042903 ! tubulin deacetylase activity +created_by: bc +creation_date: 2018-07-24T10:35:51Z + +[Term] +id: GO:0150069 +name: negative regulation of tubulin deacetylase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity." [GOC:aruk, GOC:bc, PMID:19457097] +is_a: GO:0150066 ! negative regulation of deacetylase activity +is_a: GO:0150067 ! regulation of tubulin deacetylase activity +is_a: GO:1904428 ! negative regulation of tubulin deacetylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0042903 ! tubulin deacetylase activity +relationship: negatively_regulates GO:0042903 ! tubulin deacetylase activity +created_by: bc +creation_date: 2018-07-24T10:40:19Z + +[Term] +id: GO:0150070 +name: regulation of arginase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arginase activity." [GOC:aruk, GOC:bc, PMID:26670206] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0004053 ! arginase activity +relationship: regulates GO:0004053 ! arginase activity +created_by: bc +creation_date: 2018-07-25T09:17:30Z + +[Term] +id: GO:0150071 +name: negative regulation of arginase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity." [GOC:aruk, GOC:bc] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:0150070 ! regulation of arginase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0004053 ! arginase activity +relationship: negatively_regulates GO:0004053 ! arginase activity +created_by: bc +creation_date: 2018-07-25T09:22:32Z + +[Term] +id: GO:0150072 +name: positive regulation of arginase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of arginase activity." [GOC:aruk, GOC:bc, PMID:26670206] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:0150070 ! regulation of arginase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0004053 ! arginase activity +relationship: positively_regulates GO:0004053 ! arginase activity +created_by: bc +creation_date: 2018-07-25T09:26:20Z + +[Term] +id: GO:0150073 +name: regulation of protein-glutamine gamma-glutamyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity." [GOC:aruk, GOC:bc, PMID:26670206] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +relationship: regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +created_by: bc +creation_date: 2018-07-25T10:03:10Z + +[Term] +id: GO:0150074 +name: positive regulation of protein-glutamine gamma-glutamyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity." [GOC:aruk, GOC:bc, PMID:26670206] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:0150073 ! regulation of protein-glutamine gamma-glutamyltransferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +relationship: positively_regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +created_by: bc +creation_date: 2018-07-25T10:08:19Z + +[Term] +id: GO:0150075 +name: negative regulation of protein-glutamine gamma-glutamyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity." [GOC:aruk, GOC:bc] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:0150073 ! regulation of protein-glutamine gamma-glutamyltransferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +relationship: negatively_regulates GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +created_by: bc +creation_date: 2018-07-25T10:10:24Z + +[Term] +id: GO:0150076 +name: neuroinflammatory response +namespace: biological_process +def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] +synonym: "nerve tissue inflammatory response" EXACT [] +synonym: "nervous tissue inflammatory response" EXACT [] +synonym: "neural tissue inflammatory response" EXACT [] +is_a: GO:0006954 ! inflammatory response +created_by: bc +creation_date: 2018-07-26T12:25:34Z + +[Term] +id: GO:0150077 +name: regulation of neuroinflammatory response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150076 ! neuroinflammatory response +relationship: regulates GO:0150076 ! neuroinflammatory response +created_by: bc +creation_date: 2018-07-26T12:32:18Z + +[Term] +id: GO:0150078 +name: positive regulation of neuroinflammatory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc] +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0150077 ! regulation of neuroinflammatory response +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150076 ! neuroinflammatory response +relationship: positively_regulates GO:0150076 ! neuroinflammatory response +created_by: bc +creation_date: 2018-07-26T12:35:50Z + +[Term] +id: GO:0150079 +name: negative regulation of neuroinflammatory response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423] +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0150077 ! regulation of neuroinflammatory response +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150076 ! neuroinflammatory response +relationship: negatively_regulates GO:0150076 ! neuroinflammatory response +created_by: bc +creation_date: 2018-07-26T12:38:08Z + +[Term] +id: GO:0150086 +name: multiple synapse bouton +namespace: cellular_component +def: "A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:11466428, PMID:18501438, PMID:22028887, PMID:29774619, PMID:7482800, PMID:8366344] +synonym: "MSB" EXACT [] +synonym: "multi-synapse" RELATED [] +synonym: "multi-synapse bouton" EXACT [] +synonym: "multi-synaptic bouton" EXACT [] +synonym: "multiple spine synapse bouton" EXACT [] +synonym: "multiple synapse" RELATED [] +synonym: "multiple-synapse bouton" EXACT [] +synonym: "multisynapse" RELATED [] +synonym: "multisynapse bouton" EXACT [] +synonym: "multisynaptic bouton" EXACT [] +is_a: GO:0043195 ! terminal bouton +created_by: bc +creation_date: 2018-08-08T13:21:17Z + +[Term] +id: GO:0150087 +name: multiple synapse bouton, contacting single dendrite +namespace: cellular_component +def: "A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:22028887, PMID:24487234] +synonym: "MSB1" EXACT [PMID:24487234] +synonym: "type 1 multi-synapse bouton" EXACT [PMID:24487234] +synonym: "type 1 multi-synaptic bouton" EXACT [PMID:24487234] +synonym: "type 1 multiple spine synapse bouton" EXACT [PMID:24487234] +synonym: "type 1 multiple-synapse bouton" EXACT [PMID:24487234] +synonym: "type 1 multisynapse bouton" EXACT [PMID:24487234] +synonym: "type 1 multisynaptic bouton" EXACT [PMID:24487234] +is_a: GO:0150086 ! multiple synapse bouton +created_by: bc +creation_date: 2018-08-08T13:26:34Z + +[Term] +id: GO:0150088 +name: multiple synapse bouton, contacting multiple dendrites +namespace: cellular_component +def: "A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:22028887, PMID:24487234, PMID:7482800, PMID:8366344] +synonym: "MSB2" EXACT [PMID:24487234] +synonym: "type 2 multi-synapse bouton" EXACT [PMID:24487234] +synonym: "type 2 multi-synaptic bouton" EXACT [PMID:24487234] +synonym: "type 2 multiple spine synapse bouton" EXACT [PMID:24487234] +synonym: "type 2 multiple-synapse bouton" EXACT [PMID:24487234] +synonym: "type 2 multisynapse bouton" EXACT [PMID:24487234] +synonym: "type 2 multisynaptic bouton" EXACT [PMID:24487234] +is_a: GO:0150086 ! multiple synapse bouton +created_by: bc +creation_date: 2018-08-08T13:31:43Z + +[Term] +id: GO:0150089 +name: multiple spine synapse organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:11466428, PMID:18501438, PMID:22028887, PMID:29774619, PMID:7482800, PMID:8366344] +synonym: "multi-synapse organisation" BROAD [] +synonym: "multi-synapse organization" BROAD [] +synonym: "multi-synaptic organisation" BROAD [] +synonym: "multi-synaptic organization" BROAD [] +synonym: "multiple spine synapse organisation" EXACT [] +synonym: "multisynapse organisation" BROAD [] +synonym: "multisynapse organization" BROAD [] +synonym: "multisynaptic organisation" BROAD [] +synonym: "multisynaptic organization" BROAD [] +is_a: GO:0050808 ! synapse organization +created_by: bc +creation_date: 2018-08-08T14:54:50Z + +[Term] +id: GO:0150090 +name: multiple spine synapse organization, single dendrite +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:22028887, PMID:24487234] +is_a: GO:0150089 ! multiple spine synapse organization +created_by: bc +creation_date: 2018-08-08T14:59:49Z + +[Term] +id: GO:0150091 +name: multiple spine synapse organization, multiple dendrites +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites." [GOC:aruk, GOC:bc, PMID:10586883, PMID:11248111, PMID:22028887, PMID:24487234, PMID:7482800, PMID:8366344] +is_a: GO:0150089 ! multiple spine synapse organization +created_by: bc +creation_date: 2018-08-08T15:05:29Z + +[Term] +id: GO:0150092 +name: regulation of synaptic scaling +namespace: biological_process +def: "A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell." [GOC:aruk, GOC:bc, PMID:14630218, PMID:14735113, PMID:16547515] +synonym: "homeostatic synaptic scaling" RELATED [PMID:16547515] +synonym: "regulation of homeostatic synaptic scaling" RELATED [] +is_a: GO:0048167 ! regulation of synaptic plasticity +created_by: bc +creation_date: 2018-08-09T16:27:28Z + +[Term] +id: GO:0150093 +name: amyloid-beta clearance by transcytosis +namespace: biological_process +def: "The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier." [GOC:aruk, GOC:bc, PMID:26005850] +is_a: GO:0045056 ! transcytosis +is_a: GO:0097242 ! amyloid-beta clearance +created_by: bc +creation_date: 2018-08-16T14:33:47Z + +[Term] +id: GO:0150094 +name: amyloid-beta clearance by cellular catabolic process +namespace: biological_process +def: "The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation." [GOC:aruk, GOC:bc, PMID:18289866] +synonym: "amyloid-beta clearance by phagocytosis" NARROW [] +is_a: GO:0044248 ! cellular catabolic process +is_a: GO:0097242 ! amyloid-beta clearance +created_by: bc +creation_date: 2018-08-16T14:38:09Z + +[Term] +id: GO:0150098 +name: glial cell-neuron signaling +namespace: biological_process +def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440] +synonym: "glia-neuron signaling" EXACT [] +synonym: "glia-neuron signalling" EXACT [] +synonym: "glia-neurone signaling" EXACT [] +synonym: "glia-neurone signalling" EXACT [] +synonym: "glial cell- neuron signalling" EXACT [] +synonym: "glial cell-neurone signalling" EXACT [] +synonym: "glial cell-neurone singaling" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +created_by: bc +creation_date: 2018-12-17T12:28:09Z + +[Term] +id: GO:0150099 +name: neuron-glial cell signaling +namespace: biological_process +def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368] +synonym: "neuron-glia signaling" EXACT [] +synonym: "neuron-glia signalling" EXACT [] +synonym: "neuron-glial cell signalling" EXACT [] +synonym: "neurone-glia signaling" EXACT [] +synonym: "neurone-glia signalling" EXACT [] +synonym: "neurone-glial cell signaling" EXACT [] +synonym: "neurone-glial cell signalling" EXACT [] +is_a: GO:0007267 ! cell-cell signaling +created_by: bc +creation_date: 2018-12-17T12:30:12Z + +[Term] +id: GO:0150100 +name: RNA binding involved in posttranscriptional gene silencing +namespace: molecular_function +def: "Any RNA binding that is involved in posttranscriptional gene silencing." [GOC:aruk, GOC:bc, GOC:rl, PMID:23985560, PMID:28379604] +synonym: "RNA binding involved in cosuppression" RELATED [] +synonym: "RNA binding involved in post-transcriptional gene silencing" EXACT [] +synonym: "RNA binding involved in PTGS" EXACT [] +synonym: "RNA binding involved in quelling" EXACT [] +is_a: GO:0003723 ! RNA binding +intersection_of: GO:0003723 ! RNA binding +intersection_of: part_of GO:0016441 ! posttranscriptional gene silencing +relationship: part_of GO:0016441 ! posttranscriptional gene silencing +created_by: bc +creation_date: 2019-03-11T11:48:27Z + +[Term] +id: GO:0150101 +name: regulation of microtubule anchoring at centrosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome." [GOC:aruk, GOC:bc, PMID:17139249] +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0034454 ! microtubule anchoring at centrosome +relationship: regulates GO:0034454 ! microtubule anchoring at centrosome +created_by: bc +creation_date: 2019-04-17T11:24:52Z + +[Term] +id: GO:0150102 +name: negative regulation of monocyte activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation." [GOC:aruk, PMID:15597323] +synonym: "repression of monocyte activation" EXACT [] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0042117 ! monocyte activation +relationship: regulates GO:0042117 ! monocyte activation +created_by: bc +creation_date: 2019-04-26T20:01:24Z + +[Term] +id: GO:0150103 +name: reactive gliosis +namespace: biological_process +def: "A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells." [GOC:aruk, GOC:bc, PMID:24462092] +synonym: "gliosis" BROAD [] +is_a: GO:0150076 ! neuroinflammatory response +created_by: bc +creation_date: 2019-05-21T12:37:31Z + +[Term] +id: GO:0150104 +name: transport across blood-brain barrier +namespace: biological_process +def: "The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier." [GOC:aruk, GOC:bc, PMID:29377008] +synonym: "transport across BBB" EXACT [] +synonym: "transport across blood brain barrier" EXACT [] +is_a: GO:0010232 ! vascular transport +created_by: bc +creation_date: 2019-05-27T09:12:03Z + +[Term] +id: GO:0150105 +name: protein localization to cell-cell junction +namespace: biological_process +def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] +is_a: GO:1902414 ! protein localization to cell junction +created_by: bc +creation_date: 2019-06-11T11:00:18Z + +[Term] +id: GO:0150106 +name: regulation of protein localization to cell-cell junction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] +is_a: GO:0032880 ! regulation of protein localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150105 ! protein localization to cell-cell junction +relationship: regulates GO:0150105 ! protein localization to cell-cell junction +created_by: bc +creation_date: 2019-06-11T11:17:15Z + +[Term] +id: GO:0150107 +name: positive regulation of protein localization to cell-cell junction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0150106 ! regulation of protein localization to cell-cell junction +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150105 ! protein localization to cell-cell junction +relationship: positively_regulates GO:0150105 ! protein localization to cell-cell junction +created_by: bc +creation_date: 2019-06-11T11:23:58Z + +[Term] +id: GO:0150110 +name: negative regulation of cholesterol esterification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification." [GOC:aruk, GOC:bc, PMID:21810484, PMID:24201375] +is_a: GO:0010872 ! regulation of cholesterol esterification +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045939 ! negative regulation of steroid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0034435 ! cholesterol esterification +relationship: negatively_regulates GO:0034435 ! cholesterol esterification +created_by: bc +creation_date: 2019-07-23T15:34:42Z + +[Term] +id: GO:0150111 +name: regulation of transepithelial transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0070633 ! transepithelial transport +relationship: regulates GO:0070633 ! transepithelial transport +created_by: bc +creation_date: 2019-09-15T07:16:49Z + +[Term] +id: GO:0150112 +name: regulation of interleukin-7 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-7 secretion." [GOC:aruk, PMID:25962782] +is_a: GO:0032676 ! regulation of interleukin-7 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072605 ! interleukin-7 secretion +relationship: regulates GO:0072605 ! interleukin-7 secretion +created_by: bc +creation_date: 2019-10-27T08:50:42Z + +[Term] +id: GO:0150113 +name: negative regulation of interleukin-7 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-7 secretion." [GOC:aruk, PMID:25962782] +is_a: GO:0032716 ! negative regulation of interleukin-7 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150112 ! regulation of interleukin-7 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072605 ! interleukin-7 secretion +relationship: negatively_regulates GO:0072605 ! interleukin-7 secretion +created_by: bc +creation_date: 2019-10-27T08:53:35Z + +[Term] +id: GO:0150114 +name: positive regulation of interleukin-7 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-7 secretion." [GOC:aruk] +is_a: GO:0032756 ! positive regulation of interleukin-7 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150112 ! regulation of interleukin-7 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072605 ! interleukin-7 secretion +relationship: positively_regulates GO:0072605 ! interleukin-7 secretion +created_by: bc +creation_date: 2019-10-27T08:55:49Z + +[Term] +id: GO:0150115 +name: cell-substrate junction organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix." [GOC:aruk, GOC:bc, PMID:10419689, PMID:1643657, PMID:16805308, PMID:26923917, PMID:8314002] +is_a: GO:0034330 ! cell junction organization +created_by: bc +creation_date: 2019-11-14T11:06:29Z + +[Term] +id: GO:0150116 +name: regulation of cell-substrate junction organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell-substrate junction organization." [GOC:aruk] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150115 ! cell-substrate junction organization +relationship: regulates GO:0150115 ! cell-substrate junction organization +created_by: bc +creation_date: 2019-11-14T12:12:27Z + +[Term] +id: GO:0150117 +name: positive regulation of cell-substrate junction organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization." [GOC:aruk] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0150116 ! regulation of cell-substrate junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150115 ! cell-substrate junction organization +relationship: positively_regulates GO:0150115 ! cell-substrate junction organization +created_by: bc +creation_date: 2019-11-14T12:15:07Z + +[Term] +id: GO:0150118 +name: negative regulation of cell-substrate junction organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization." [GOC:aruk] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0150116 ! regulation of cell-substrate junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150115 ! cell-substrate junction organization +relationship: negatively_regulates GO:0150115 ! cell-substrate junction organization +created_by: bc +creation_date: 2019-11-14T12:16:32Z + +[Term] +id: GO:0150119 +name: negative regulation of protein localization to cell-cell junction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc] +synonym: "negative regulation of protein localisation to cell-cell junction" EXACT [] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0150106 ! regulation of protein localization to cell-cell junction +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150105 ! protein localization to cell-cell junction +relationship: negatively_regulates GO:0150105 ! protein localization to cell-cell junction +created_by: bc +creation_date: 2019-11-21T13:53:34Z + +[Term] +id: GO:0150120 +name: regulation of interleukin-18 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-18 secretion." [GOC:aruk, PMID:23710316] +is_a: GO:0032661 ! regulation of interleukin-18 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072616 ! interleukin-18 secretion +relationship: regulates GO:0072616 ! interleukin-18 secretion +created_by: bc +creation_date: 2019-11-27T11:37:50Z + +[Term] +id: GO:0150121 +name: negative regulation of interleukin-18 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18 secretion." [GOC:aruk, PMID:23710316] +is_a: GO:0032701 ! negative regulation of interleukin-18 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150120 ! regulation of interleukin-18 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072616 ! interleukin-18 secretion +relationship: negatively_regulates GO:0072616 ! interleukin-18 secretion +created_by: bc +creation_date: 2019-11-27T11:40:37Z + +[Term] +id: GO:0150122 +name: positive regulation of interleukin-18 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-18 secretion." [GOC:aruk] +is_a: GO:0032741 ! positive regulation of interleukin-18 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150120 ! regulation of interleukin-18 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072616 ! interleukin-18 secretion +relationship: positively_regulates GO:0072616 ! interleukin-18 secretion +created_by: bc +creation_date: 2019-11-27T11:44:29Z + +[Term] +id: GO:0150123 +name: regulation of interleukin-33 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-33 biosynthetic process." [GOC:aruk, PMID:29778524] +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +is_a: GO:0150127 ! regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150126 ! interleukin-33 biosynthetic process +relationship: regulates GO:0150126 ! interleukin-33 biosynthetic process +created_by: bc +creation_date: 2019-12-01T16:39:17Z + +[Term] +id: GO:0150124 +name: negative regulation of interleukin-33 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 biosynthetic process." [GOC:aruk, PMID:29778524] +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0150123 ! regulation of interleukin-33 biosynthetic process +is_a: GO:0150128 ! negative regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150126 ! interleukin-33 biosynthetic process +relationship: negatively_regulates GO:0150126 ! interleukin-33 biosynthetic process +created_by: bc +creation_date: 2019-12-01T16:39:36Z + +[Term] +id: GO:0150125 +name: positive regulation of interleukin-33 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-33 biosynthetic process." [GOC:aruk] +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0150123 ! regulation of interleukin-33 biosynthetic process +is_a: GO:0150129 ! positive regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150126 ! interleukin-33 biosynthetic process +relationship: positively_regulates GO:0150126 ! interleukin-33 biosynthetic process +created_by: bc +creation_date: 2019-12-01T16:39:45Z + +[Term] +id: GO:0150126 +name: interleukin-33 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-33." [GOC:aruk, PMID:29778524] +is_a: GO:0042089 ! cytokine biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +relationship: part_of GO:0072639 ! interleukin-33 production +created_by: bc +creation_date: 2019-12-01T16:46:17Z + +[Term] +id: GO:0150127 +name: regulation of interleukin-33 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-33 production." [GOC:aruk, PMID:29778524] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072639 ! interleukin-33 production +relationship: regulates GO:0072639 ! interleukin-33 production +created_by: bc +creation_date: 2019-12-01T17:05:01Z + +[Term] +id: GO:0150128 +name: negative regulation of interleukin-33 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production." [GOC:aruk, PMID:29778524] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0150127 ! regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072639 ! interleukin-33 production +relationship: negatively_regulates GO:0072639 ! interleukin-33 production +created_by: bc +creation_date: 2019-12-01T17:08:31Z + +[Term] +id: GO:0150129 +name: positive regulation of interleukin-33 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-33 production." [GOC:aruk] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0150127 ! regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072639 ! interleukin-33 production +relationship: positively_regulates GO:0072639 ! interleukin-33 production +created_by: bc +creation_date: 2019-12-01T17:10:56Z + +[Term] +id: GO:0150130 +name: regulation of interleukin-33 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-33 secretion." [GOC:aruk, PMID:29778524] +is_a: GO:0050707 ! regulation of cytokine secretion +is_a: GO:0150127 ! regulation of interleukin-33 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072640 ! interleukin-33 secretion +relationship: regulates GO:0072640 ! interleukin-33 secretion +created_by: bc +creation_date: 2019-12-03T05:54:03Z + +[Term] +id: GO:0150131 +name: negative regulation of interleukin-33 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 secretion." [GOC:aruk, PMID:29778524] +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150128 ! negative regulation of interleukin-33 production +is_a: GO:0150130 ! regulation of interleukin-33 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072640 ! interleukin-33 secretion +relationship: negatively_regulates GO:0072640 ! interleukin-33 secretion +created_by: bc +creation_date: 2019-12-03T05:54:24Z + +[Term] +id: GO:0150132 +name: positive regulation of interleukin-33 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-33 secretion." [GOC:aruk] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150129 ! positive regulation of interleukin-33 production +is_a: GO:0150130 ! regulation of interleukin-33 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072640 ! interleukin-33 secretion +relationship: positively_regulates GO:0072640 ! interleukin-33 secretion +created_by: bc +creation_date: 2019-12-03T05:54:37Z + +[Term] +id: GO:0150133 +name: regulation of interleukin-4 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-4 secretion." [GOC:aruk, PMID:29778524] +is_a: GO:0032673 ! regulation of interleukin-4 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072602 ! interleukin-4 secretion +relationship: regulates GO:0072602 ! interleukin-4 secretion +created_by: bc +creation_date: 2019-12-03T11:33:28Z + +[Term] +id: GO:0150134 +name: negative regulation of interleukin-4 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4 secretion." [GOC:aruk, PMID:29778524] +is_a: GO:0032713 ! negative regulation of interleukin-4 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150133 ! regulation of interleukin-4 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072602 ! interleukin-4 secretion +relationship: negatively_regulates GO:0072602 ! interleukin-4 secretion +created_by: bc +creation_date: 2019-12-03T11:33:56Z + +[Term] +id: GO:0150135 +name: positive regulation of interleukin-4 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-4 secretion." [GOC:aruk] +is_a: GO:0032753 ! positive regulation of interleukin-4 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150133 ! regulation of interleukin-4 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072602 ! interleukin-4 secretion +relationship: positively_regulates GO:0072602 ! interleukin-4 secretion +created_by: bc +creation_date: 2019-12-03T11:35:42Z + +[Term] +id: GO:0150136 +name: regulation of interleukin-37 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-37 biosynthetic process." [GOC:aruk, PMID:30362558] +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150137 ! interleukin-37 biosynthetic process +relationship: regulates GO:0150137 ! interleukin-37 biosynthetic process +created_by: bc +creation_date: 2019-12-08T08:39:07Z + +[Term] +id: GO:0150137 +name: interleukin-37 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-37." [GOC:aruk, PMID:30362558] +is_a: GO:0042089 ! cytokine biosynthetic process +created_by: bc +creation_date: 2019-12-08T08:43:09Z + +[Term] +id: GO:0150138 +name: negative regulation of interleukin-37 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 biosynthetic process." [GOC:aruk, PMID:30362558] +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0150136 ! regulation of interleukin-37 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150137 ! interleukin-37 biosynthetic process +relationship: negatively_regulates GO:0150137 ! interleukin-37 biosynthetic process +created_by: bc +creation_date: 2019-12-08T08:45:29Z + +[Term] +id: GO:0150139 +name: positive regulation of interleukin-37 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-37 biosynthetic process." [GOC:aruk] +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0150136 ! regulation of interleukin-37 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150137 ! interleukin-37 biosynthetic process +relationship: positively_regulates GO:0150137 ! interleukin-37 biosynthetic process +created_by: bc +creation_date: 2019-12-08T08:47:29Z + +[Term] +id: GO:0150140 +name: regulation of CD86 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD86 biosynthetic process." [GOC:aruk, PMID:26936882] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0035781 ! CD86 biosynthetic process +relationship: regulates GO:0035781 ! CD86 biosynthetic process +created_by: bc +creation_date: 2019-12-08T09:31:00Z + +[Term] +id: GO:0150141 +name: negative regulation of CD86 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process." [GOC:aruk, PMID:26936882] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0150140 ! regulation of CD86 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0035781 ! CD86 biosynthetic process +relationship: negatively_regulates GO:0035781 ! CD86 biosynthetic process +created_by: bc +creation_date: 2019-12-08T09:33:39Z + +[Term] +id: GO:0150142 +name: positive regulation of CD86 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process." [GOC:aruk] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0150140 ! regulation of CD86 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0035781 ! CD86 biosynthetic process +relationship: positively_regulates GO:0035781 ! CD86 biosynthetic process +created_by: bc +creation_date: 2019-12-08T09:35:35Z + +[Term] +id: GO:0150143 +name: regulation of CD80 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD80 biosynthetic process." [GOC:aruk, PMID:26936882] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0035780 ! CD80 biosynthetic process +relationship: regulates GO:0035780 ! CD80 biosynthetic process +created_by: bc +creation_date: 2019-12-08T10:23:43Z + +[Term] +id: GO:0150144 +name: negative regulation of CD80 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process." [GOC:aruk, PMID:26936882] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +is_a: GO:0150143 ! regulation of CD80 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0035780 ! CD80 biosynthetic process +relationship: negatively_regulates GO:0035780 ! CD80 biosynthetic process +created_by: bc +creation_date: 2019-12-08T10:26:42Z + +[Term] +id: GO:0150145 +name: positive regulation of CD80 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process." [GOC:aruk] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:0150143 ! regulation of CD80 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0035780 ! CD80 biosynthetic process +relationship: positively_regulates GO:0035780 ! CD80 biosynthetic process +created_by: bc +creation_date: 2019-12-08T10:29:00Z + +[Term] +id: GO:0150146 +name: cell junction disassembly +namespace: biological_process +def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0034330 ! cell junction organization +created_by: bc +creation_date: 2019-12-08T11:12:13Z + +[Term] +id: GO:0150147 +name: cell-cell junction disassembly +namespace: biological_process +def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267] +is_a: GO:0045216 ! cell-cell junction organization +is_a: GO:0150146 ! cell junction disassembly +created_by: bc +creation_date: 2019-12-08T11:16:14Z + +[Term] +id: GO:0150148 +name: regulation of interleukin-25 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-25 secretion." [GOC:aruk, PMID:27901018] +is_a: GO:0032669 ! regulation of interleukin-25 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072623 ! interleukin-25 secretion +relationship: regulates GO:0072623 ! interleukin-25 secretion +created_by: bc +creation_date: 2019-12-09T16:51:07Z + +[Term] +id: GO:0150149 +name: negative regulation of interleukin-25 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-25 secretion." [GOC:aruk, PMID:27901018] +is_a: GO:0032709 ! negative regulation of interleukin-25 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150148 ! regulation of interleukin-25 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072623 ! interleukin-25 secretion +relationship: negatively_regulates GO:0072623 ! interleukin-25 secretion +created_by: bc +creation_date: 2019-12-09T16:51:28Z + +[Term] +id: GO:0150150 +name: positive regulation of interleukin-25 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-25 secretion." [GOC:aruk] +is_a: GO:0032749 ! positive regulation of interleukin-25 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150148 ! regulation of interleukin-25 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072623 ! interleukin-25 secretion +relationship: positively_regulates GO:0072623 ! interleukin-25 secretion +created_by: bc +creation_date: 2019-12-09T16:51:44Z + +[Term] +id: GO:0150151 +name: regulation of interleukin-17A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-17A biosynthetic process." [GOC:aruk, PMID:27901018] +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150154 ! interleukin-17A biosynthetic process +relationship: regulates GO:0150154 ! interleukin-17A biosynthetic process +created_by: bc +creation_date: 2019-12-11T07:44:52Z + +[Term] +id: GO:0150152 +name: negative regulation of interleukin-17A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A biosynthetic process." [GOC:aruk, PMID:27901018] +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0150151 ! regulation of interleukin-17A biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150154 ! interleukin-17A biosynthetic process +relationship: negatively_regulates GO:0150154 ! interleukin-17A biosynthetic process +created_by: bc +creation_date: 2019-12-11T07:45:24Z + +[Term] +id: GO:0150153 +name: positive regulation of interleukin-17A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-17A biosynthetic process." [GOC:aruk] +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0150151 ! regulation of interleukin-17A biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150154 ! interleukin-17A biosynthetic process +relationship: positively_regulates GO:0150154 ! interleukin-17A biosynthetic process +created_by: bc +creation_date: 2019-12-11T07:45:44Z + +[Term] +id: GO:0150154 +name: interleukin-17A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-17A." [GOC:aruk, PMID:27901018] +is_a: GO:0042089 ! cytokine biosynthetic process +created_by: bc +creation_date: 2019-12-11T07:55:52Z + +[Term] +id: GO:0150155 +name: interleukin-34 production +namespace: biological_process +def: "The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:aruk, PMID:26754294] +is_a: GO:0001816 ! cytokine production +created_by: bc +creation_date: 2020-01-06T16:25:25Z + +[Term] +id: GO:0150156 +name: interleukin-34 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-34." [GOC:aruk, PMID:26754294] +is_a: GO:0042089 ! cytokine biosynthetic process +relationship: part_of GO:0150155 ! interleukin-34 production +created_by: bc +creation_date: 2020-01-06T16:26:08Z + +[Term] +id: GO:0150157 +name: regulation of interleukin-34 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-34 production." [GOC:aruk, PMID:26754294] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150155 ! interleukin-34 production +relationship: regulates GO:0150155 ! interleukin-34 production +created_by: bc +creation_date: 2020-01-06T16:30:44Z + +[Term] +id: GO:0150158 +name: positive regulation of interleukin-34 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-34 production." [GOC:aruk] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0150157 ! regulation of interleukin-34 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150155 ! interleukin-34 production +relationship: positively_regulates GO:0150155 ! interleukin-34 production +created_by: bc +creation_date: 2020-01-06T16:31:00Z + +[Term] +id: GO:0150159 +name: negative regulation of interleukin-34 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production." [GOC:aruk, PMID:26754294] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0150157 ! regulation of interleukin-34 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150155 ! interleukin-34 production +relationship: negatively_regulates GO:0150155 ! interleukin-34 production +created_by: bc +creation_date: 2020-01-06T16:31:12Z + +[Term] +id: GO:0150160 +name: regulation of interleukin-34 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-34 biosynthetic process." [GOC:aruk, PMID:26754294] +is_a: GO:0042035 ! regulation of cytokine biosynthetic process +is_a: GO:0150157 ! regulation of interleukin-34 production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150156 ! interleukin-34 biosynthetic process +relationship: regulates GO:0150156 ! interleukin-34 biosynthetic process +created_by: bc +creation_date: 2020-01-06T16:31:29Z + +[Term] +id: GO:0150161 +name: positive regulation of interleukin-34 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-34 biosynthetic process." [GOC:aruk] +is_a: GO:0042108 ! positive regulation of cytokine biosynthetic process +is_a: GO:0150158 ! positive regulation of interleukin-34 production +is_a: GO:0150160 ! regulation of interleukin-34 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150156 ! interleukin-34 biosynthetic process +relationship: positively_regulates GO:0150156 ! interleukin-34 biosynthetic process +created_by: bc +creation_date: 2020-01-06T16:32:11Z + +[Term] +id: GO:0150162 +name: negative regulation of interleukin-34 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 biosynthetic process." [GOC:aruk, PMID:26754294] +is_a: GO:0042036 ! negative regulation of cytokine biosynthetic process +is_a: GO:0150159 ! negative regulation of interleukin-34 production +is_a: GO:0150160 ! regulation of interleukin-34 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150156 ! interleukin-34 biosynthetic process +relationship: negatively_regulates GO:0150156 ! interleukin-34 biosynthetic process +created_by: bc +creation_date: 2020-01-06T16:32:23Z + +[Term] +id: GO:0150163 +name: miRNA-mediated activation of transcription by RNA polymerase II +namespace: biological_process +def: "Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:aruk, PMID:20737563, PMID:27145859] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0150164 ! miRNA-mediated regulation of transcription by RNA polymerase II +is_a: GO:1903313 ! positive regulation of mRNA metabolic process +relationship: positively_regulates GO:0042789 ! mRNA transcription by RNA polymerase II +created_by: bc +creation_date: 2020-01-14T12:08:14Z + +[Term] +id: GO:0150164 +name: miRNA-mediated regulation of transcription by RNA polymerase II +namespace: biological_process +def: "Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:aruk, PMID:20737563, PMID:27145859] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:1903311 ! regulation of mRNA metabolic process +relationship: regulates GO:0042789 ! mRNA transcription by RNA polymerase II +created_by: bc +creation_date: 2020-01-14T12:16:32Z + +[Term] +id: GO:0150165 +name: miRNA-mediated inhibition of transcription by RNA polymerase II +namespace: biological_process +def: "Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:aruk] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0150164 ! miRNA-mediated regulation of transcription by RNA polymerase II +is_a: GO:1903312 ! negative regulation of mRNA metabolic process +relationship: negatively_regulates GO:0042789 ! mRNA transcription by RNA polymerase II +created_by: bc +creation_date: 2020-01-14T12:21:12Z + +[Term] +id: GO:0150166 +name: regulation of histone H3-K4 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation." [GOC:aruk] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0043973 ! histone H3-K4 acetylation +relationship: regulates GO:0043973 ! histone H3-K4 acetylation +created_by: bc +creation_date: 2020-01-14T12:27:26Z + +[Term] +id: GO:0150167 +name: positive regulation of histone H3-K4 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K4 acetylation." [GOC:aruk, PMID:20737563] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:0150166 ! regulation of histone H3-K4 acetylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0043973 ! histone H3-K4 acetylation +relationship: positively_regulates GO:0043973 ! histone H3-K4 acetylation +created_by: bc +creation_date: 2020-01-14T12:32:18Z + +[Term] +id: GO:0150168 +name: negative regulation of histone H3-K4 acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation." [GOC:aruk] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:0150166 ! regulation of histone H3-K4 acetylation +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0043973 ! histone H3-K4 acetylation +relationship: negatively_regulates GO:0043973 ! histone H3-K4 acetylation +created_by: bc +creation_date: 2020-01-14T12:34:01Z + +[Term] +id: GO:0150169 +name: regulation of interleukin-11 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-11 secretion." [GOC:aruk, PMID:29286137] +is_a: GO:0032654 ! regulation of interleukin-11 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072609 ! interleukin-11 secretion +relationship: regulates GO:0072609 ! interleukin-11 secretion +created_by: bc +creation_date: 2020-01-19T10:39:24Z + +[Term] +id: GO:0150170 +name: negative regulation of interleukin-11 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-11 secretion." [GOC:aruk, PMID:29286137] +is_a: GO:0032694 ! negative regulation of interleukin-11 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150169 ! regulation of interleukin-11 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072609 ! interleukin-11 secretion +relationship: negatively_regulates GO:0072609 ! interleukin-11 secretion +created_by: bc +creation_date: 2020-01-19T10:39:45Z + +[Term] +id: GO:0150171 +name: positive regulation of interleukin-11 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-11 secretion." [GOC:aruk] +is_a: GO:0032734 ! positive regulation of interleukin-11 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150169 ! regulation of interleukin-11 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072609 ! interleukin-11 secretion +relationship: positively_regulates GO:0072609 ! interleukin-11 secretion +created_by: bc +creation_date: 2020-01-19T10:40:06Z + +[Term] +id: GO:0150172 +name: regulation of phosphatidylcholine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0046470 ! phosphatidylcholine metabolic process +relationship: regulates GO:0046470 ! phosphatidylcholine metabolic process +created_by: bc +creation_date: 2020-01-21T14:03:11Z + +[Term] +id: GO:0150173 +name: positive regulation of phosphatidylcholine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0150172 ! regulation of phosphatidylcholine metabolic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0046470 ! phosphatidylcholine metabolic process +relationship: positively_regulates GO:0046470 ! phosphatidylcholine metabolic process +created_by: bc +creation_date: 2020-01-21T14:03:28Z + +[Term] +id: GO:0150174 +name: negative regulation of phosphatidylcholine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0065007 ! biological regulation +created_by: bc +creation_date: 2020-01-21T14:03:53Z + +[Term] +id: GO:0150175 +name: regulation of phosphatidylethanolamine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0046337 ! phosphatidylethanolamine metabolic process +relationship: regulates GO:0046337 ! phosphatidylethanolamine metabolic process +created_by: bc +creation_date: 2020-01-21T14:04:12Z + +[Term] +id: GO:0150176 +name: positive regulation of phosphatidylethanolamine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0150175 ! regulation of phosphatidylethanolamine metabolic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0046337 ! phosphatidylethanolamine metabolic process +relationship: positively_regulates GO:0046337 ! phosphatidylethanolamine metabolic process +created_by: bc +creation_date: 2020-01-21T14:04:32Z + +[Term] +id: GO:0150177 +name: negative regulation of phosphatidylethanolamine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0150175 ! regulation of phosphatidylethanolamine metabolic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0046337 ! phosphatidylethanolamine metabolic process +relationship: negatively_regulates GO:0046337 ! phosphatidylethanolamine metabolic process +created_by: bc +creation_date: 2020-01-21T14:05:00Z + +[Term] +id: GO:0150178 +name: regulation of phosphatidylserine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0006658 ! phosphatidylserine metabolic process +relationship: regulates GO:0006658 ! phosphatidylserine metabolic process +created_by: bc +creation_date: 2020-01-21T14:05:21Z + +[Term] +id: GO:0150179 +name: positive regulation of phosphatidylserine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0150178 ! regulation of phosphatidylserine metabolic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0006658 ! phosphatidylserine metabolic process +relationship: positively_regulates GO:0006658 ! phosphatidylserine metabolic process +created_by: bc +creation_date: 2020-01-21T14:05:52Z + +[Term] +id: GO:0150180 +name: negative regulation of phosphatidylserine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process." [GOC:aruk, GOC:bc, PMID:30074985] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0150178 ! regulation of phosphatidylserine metabolic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0006658 ! phosphatidylserine metabolic process +relationship: negatively_regulates GO:0006658 ! phosphatidylserine metabolic process +created_by: bc +creation_date: 2020-01-21T14:06:06Z + +[Term] +id: GO:0150188 +name: interleukin-32 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of interleukin-32." [GOC:aruk, PMID:23729669] +is_a: GO:0072637 ! interleukin-32 production +created_by: bc +creation_date: 2020-02-21T10:26:40Z + +[Term] +id: GO:0150189 +name: regulation of interleukin-32 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-32 biosynthetic process." [GOC:aruk, PMID:23729669] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150188 ! interleukin-32 biosynthetic process +relationship: regulates GO:0150188 ! interleukin-32 biosynthetic process +created_by: bc +creation_date: 2020-02-21T10:28:36Z + +[Term] +id: GO:0150190 +name: negative regulation of interleukin-32 biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 biosynthetic process." [GOC:aruk, PMID:23729669] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0150189 ! regulation of interleukin-32 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150188 ! interleukin-32 biosynthetic process +relationship: negatively_regulates GO:0150188 ! interleukin-32 biosynthetic process +created_by: bc +creation_date: 2020-02-21T10:31:53Z + +[Term] +id: GO:0150191 +name: positive regulation of interleukin-32 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-32 biosynthetic process." [GOC:aruk] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0150189 ! regulation of interleukin-32 biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150188 ! interleukin-32 biosynthetic process +relationship: positively_regulates GO:0150188 ! interleukin-32 biosynthetic process +created_by: bc +creation_date: 2020-02-21T10:33:39Z + +[Term] +id: GO:0150192 +name: regulation of interleukin-32 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-32 secretion." [GOC:aruk, PMID:23729669] +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0072638 ! interleukin-32 secretion +relationship: regulates GO:0072638 ! interleukin-32 secretion +created_by: bc +creation_date: 2020-02-21T10:34:56Z + +[Term] +id: GO:0150193 +name: negative regulation of interleukin-32 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 secretion." [GOC:aruk, PMID:23729669] +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:0150192 ! regulation of interleukin-32 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0072638 ! interleukin-32 secretion +relationship: negatively_regulates GO:0072638 ! interleukin-32 secretion +created_by: bc +creation_date: 2020-02-21T10:36:37Z + +[Term] +id: GO:0150194 +name: positive regulation of interleukin-32 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-32 secretion." [GOC:aruk] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:0150192 ! regulation of interleukin-32 secretion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0072638 ! interleukin-32 secretion +relationship: positively_regulates GO:0072638 ! interleukin-32 secretion +created_by: bc +creation_date: 2020-02-21T10:40:55Z + +[Term] +id: GO:0150195 +name: transport across blood-cerebrospinal fluid barrier +namespace: biological_process +def: "The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier." [GOC:aruk, GOC:bc, PMID:21349151] +synonym: "transport across BCSFB" EXACT [] +synonym: "transport across blood-CSF barrier" EXACT [] +synonym: "transport across blood/cerebrospinal fluid barrier" EXACT [] +synonym: "transport across blood/CSF barrier" EXACT [] +is_a: GO:0010232 ! vascular transport +created_by: bc +creation_date: 2020-03-26T14:43:04Z + +[Term] +id: GO:0150200 +name: regulation of transport across blood-brain barrier +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier." [GOC:aruk, GOC:bc, PMID:29377008, PMID:30280653] +is_a: GO:0044057 ! regulation of system process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0150104 ! transport across blood-brain barrier +relationship: part_of GO:0043114 ! regulation of vascular permeability +relationship: regulates GO:0150104 ! transport across blood-brain barrier +created_by: bc +creation_date: 2020-03-26T19:22:26Z + +[Term] +id: GO:0150201 +name: positive regulation of transport across blood-brain barrier +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier." [GOC:aruk, GOC:bc, PMID:29377008, PMID:30280653] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0150200 ! regulation of transport across blood-brain barrier +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0150104 ! transport across blood-brain barrier +relationship: part_of GO:0043117 ! positive regulation of vascular permeability +relationship: positively_regulates GO:0150104 ! transport across blood-brain barrier +created_by: bc +creation_date: 2020-03-26T19:26:38Z + +[Term] +id: GO:0150202 +name: negative regulation of transport across blood-brain barrier +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier." [GOC:aruk, GOC:bc, PMID:29377008, PMID:30280653] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0150200 ! regulation of transport across blood-brain barrier +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0150104 ! transport across blood-brain barrier +relationship: negatively_regulates GO:0150104 ! transport across blood-brain barrier +relationship: part_of GO:0043116 ! negative regulation of vascular permeability +created_by: bc +creation_date: 2020-03-26T19:28:51Z + +[Term] +id: GO:0198738 +name: cell-cell signaling by wnt +namespace: biological_process +def: "Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell." [GOC:dos] +is_a: GO:0007267 ! cell-cell signaling + +[Term] +id: GO:1900000 +name: regulation of anthocyanin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anthocyanin catabolic process." [GOC:TermGenie] +synonym: "regulation of anthocyanin breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of anthocyanin catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of anthocyanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0009894 ! regulation of catabolic process +is_a: GO:0031537 ! regulation of anthocyanin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046284 ! anthocyanin-containing compound catabolic process +relationship: regulates GO:0046284 ! anthocyanin-containing compound catabolic process +created_by: tb +creation_date: 2011-12-20T07:12:07Z + +[Term] +id: GO:1900001 +name: negative regulation of anthocyanin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process." [GOC:TermGenie] +synonym: "down regulation of anthocyanin breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of anthocyanin catabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of anthocyanin catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of anthocyanin degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of anthocyanin breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of anthocyanin catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of anthocyanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0031538 ! negative regulation of anthocyanin metabolic process +is_a: GO:1900000 ! regulation of anthocyanin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046284 ! anthocyanin-containing compound catabolic process +relationship: negatively_regulates GO:0046284 ! anthocyanin-containing compound catabolic process +created_by: tb +creation_date: 2011-12-20T07:12:11Z + +[Term] +id: GO:1900002 +name: positive regulation of anthocyanin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process." [GOC:TermGenie] +synonym: "positive regulation of anthocyanin breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of anthocyanin catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of anthocyanin degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of anthocyanin breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of anthocyanin catabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of anthocyanin catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of anthocyanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0031539 ! positive regulation of anthocyanin metabolic process +is_a: GO:1900000 ! regulation of anthocyanin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046284 ! anthocyanin-containing compound catabolic process +relationship: positively_regulates GO:0046284 ! anthocyanin-containing compound catabolic process +created_by: tb +creation_date: 2011-12-20T07:12:15Z + +[Term] +id: GO:1900003 +name: regulation of serine-type endopeptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] +synonym: "regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] +is_a: GO:0052548 ! regulation of endopeptidase activity +is_a: GO:1902571 ! regulation of serine-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004252 ! serine-type endopeptidase activity +relationship: regulates GO:0004252 ! serine-type endopeptidase activity +created_by: kmv +creation_date: 2012-01-09T10:03:15Z + +[Term] +id: GO:1900004 +name: negative regulation of serine-type endopeptidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] +synonym: "down regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] +synonym: "down regulation of serine-type endopeptidase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] +is_a: GO:0010951 ! negative regulation of endopeptidase activity +is_a: GO:1900003 ! regulation of serine-type endopeptidase activity +is_a: GO:1902572 ! negative regulation of serine-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004252 ! serine-type endopeptidase activity +relationship: negatively_regulates GO:0004252 ! serine-type endopeptidase activity +created_by: kmv +creation_date: 2012-01-09T10:03:20Z + +[Term] +id: GO:1900005 +name: positive regulation of serine-type endopeptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] +synonym: "positive regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of serine-type endopeptidase activity" RELATED [GOC:TermGenie] +is_a: GO:0010950 ! positive regulation of endopeptidase activity +is_a: GO:1900003 ! regulation of serine-type endopeptidase activity +is_a: GO:1902573 ! positive regulation of serine-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004252 ! serine-type endopeptidase activity +relationship: positively_regulates GO:0004252 ! serine-type endopeptidase activity +created_by: kmv +creation_date: 2012-01-09T10:03:29Z + +[Term] +id: GO:1900006 +name: positive regulation of dendrite development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendrite development." [GOC:TermGenie] +synonym: "up regulation of dendrite development" RELATED [GOC:TermGenie] +is_a: GO:0010976 ! positive regulation of neuron projection development +is_a: GO:0050773 ! regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016358 ! dendrite development +relationship: positively_regulates GO:0016358 ! dendrite development +created_by: hjd +creation_date: 2012-01-09T10:41:31Z + +[Term] +id: GO:1900007 +name: regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging." [GOC:TermGenie, PMID:15020466] +synonym: "regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [GOC:TermGenie] +synonym: "regulation of extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +is_a: GO:1900062 ! regulation of replicative cell aging +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +relationship: regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +created_by: se +creation_date: 2012-01-09T10:44:07Z + +[Term] +id: GO:1900008 +name: negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging." [GOC:TermGenie, PMID:15020466] +synonym: "down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [GOC:TermGenie] +synonym: "down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging" RELATED [GOC:TermGenie] +synonym: "down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [GOC:TermGenie] +synonym: "negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +is_a: GO:0090344 ! negative regulation of cell aging +is_a: GO:1900007 ! regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +relationship: negatively_regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +created_by: se +creation_date: 2012-01-09T10:44:10Z + +[Term] +id: GO:1900009 +name: positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging." [GOC:TermGenie, PMID:15020466] +synonym: "positive regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [GOC:TermGenie] +synonym: "positive regulation of extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "positive regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "up regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing" RELATED [GOC:TermGenie] +synonym: "up regulation of extrachromosomal rDNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +synonym: "up regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging" RELATED [GOC:TermGenie] +synonym: "up regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging" RELATED [GOC:TermGenie] +is_a: GO:0090343 ! positive regulation of cell aging +is_a: GO:1900007 ! regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +relationship: positively_regulates GO:0001310 ! extrachromosomal rDNA circle accumulation involved in replicative cell aging +created_by: se +creation_date: 2012-01-09T10:44:18Z + +[Term] +id: GO:1900010 +name: regulation of corticotropin-releasing hormone receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity." [GOC:TermGenie, GOC:yaf, PMID:18234674] +synonym: "regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] +synonym: "regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] +synonym: "regulation of CRF receptor activity" EXACT [GOC:TermGenie] +synonym: "regulation of CRH receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +relationship: regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +created_by: pr +creation_date: 2012-01-10T02:27:23Z + +[Term] +id: GO:1900011 +name: negative regulation of corticotropin-releasing hormone receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity." [GOC:TermGenie, GOC:yaf, PMID:18234674] +synonym: "down regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of corticotropin-releasing hormone receptor activity" RELATED [GOC:TermGenie] +synonym: "down regulation of CRF receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CRH receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CRF receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CRH receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900010 ! regulation of corticotropin-releasing hormone receptor activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +relationship: negatively_regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +created_by: pr +creation_date: 2012-01-10T02:27:27Z + +[Term] +id: GO:1900012 +name: positive regulation of corticotropin-releasing hormone receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity." [GOC:TermGenie, GOC:yaf, PMID:18234674] +synonym: "positive regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CRF receptor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CRH receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of corticotropin-releasing hormone receptor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of CRF receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CRH receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900010 ! regulation of corticotropin-releasing hormone receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +relationship: positively_regulates GO:0043404 ! corticotropin-releasing hormone receptor activity +created_by: pr +creation_date: 2012-01-10T02:27:30Z + +[Term] +id: GO:1900013 +name: obsolete cellular response to potassium ion involved in chemotaxis to cAMP +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus." [GOC:pf, GOC:TermGenie, PMID:19363786, PMID:21239624] +comment: This term was made obsolete because it was added by mistake. +synonym: "cellular response to K+ ion of chemotaxis to 3',5' cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to K+ ion of chemotaxis to 3',5'-cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to K+ ion of chemotaxis to adenosine 3',5'-cyclophosphate" EXACT [GOC:TermGenie] +synonym: "cellular response to K+ ion of chemotaxis to cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to K+ ion of chemotaxis to cyclic AMP" EXACT [GOC:TermGenie] +synonym: "cellular response to potassium ion involved in chemotaxis to cAMP" EXACT [] +synonym: "cellular response to potassium ion of chemotaxis to 3',5' cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium ion of chemotaxis to 3',5'-cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium ion of chemotaxis to adenosine 3',5'-cyclophosphate" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium ion of chemotaxis to cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium ion of chemotaxis to cyclic AMP" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium of chemotaxis to 3',5' cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to potassium of chemotaxis to 3',5'-cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to potassium of chemotaxis to adenosine 3',5'-cyclophosphate" EXACT [GOC:TermGenie] +synonym: "cellular response to potassium of chemotaxis to cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to potassium of chemotaxis to cyclic AMP" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2012-01-11T07:59:57Z + +[Term] +id: GO:1900014 +name: obsolete cellular response to calcium ion involved in chemotaxis to cAMP +namespace: biological_process +def: "OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." [GOC:pf, GOC:TermGenie, PMID:19363786, PMID:21239624, PMID:8937985] +synonym: "cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP" EXACT [GOC:TermGenie] +synonym: "cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate" EXACT [GOC:TermGenie] +synonym: "cellular response to Ca2+ ion of chemotaxis to cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to Ca2+ ion of chemotaxis to cyclic AMP" EXACT [GOC:TermGenie] +synonym: "cellular response to calcium ion involved in chemotaxis to cAMP" EXACT [] +synonym: "cellular response to calcium ion of chemotaxis to 3',5' cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to calcium ion of chemotaxis to 3',5'-cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate" RELATED [GOC:TermGenie] +synonym: "cellular response to calcium ion of chemotaxis to cAMP" RELATED [GOC:TermGenie] +synonym: "cellular response to calcium ion of chemotaxis to cyclic AMP" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2012-01-11T08:06:58Z + +[Term] +id: GO:1900015 +name: regulation of cytokine production involved in inflammatory response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] +synonym: "regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] +is_a: GO:0001817 ! regulation of cytokine production +is_a: GO:0050727 ! regulation of inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002534 ! cytokine production involved in inflammatory response +relationship: regulates GO:0002534 ! cytokine production involved in inflammatory response +created_by: rph +creation_date: 2012-01-11T09:34:27Z + +[Term] +id: GO:1900016 +name: negative regulation of cytokine production involved in inflammatory response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] +synonym: "down regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] +synonym: "down regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] +synonym: "negative regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response +relationship: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response +created_by: rph +creation_date: 2012-01-11T09:34:31Z + +[Term] +id: GO:1900017 +name: positive regulation of cytokine production involved in inflammatory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] +synonym: "positive regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] +synonym: "up regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] +synonym: "up regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response +relationship: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response +created_by: rph +creation_date: 2012-01-11T09:34:35Z + +[Term] +id: GO:1900018 +name: phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex +namespace: biological_process +def: "Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex." [GOC:rb, GOC:TermGenie, PMID:10594013, PMID:19666497] +is_a: GO:0071620 ! phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +intersection_of: GO:0071620 ! phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +intersection_of: part_of GO:0036031 ! recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex +relationship: part_of GO:0036031 ! recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex +created_by: bf +creation_date: 2012-01-11T11:40:41Z + +[Term] +id: GO:1900019 +name: regulation of protein kinase C activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein kinase C activity." [GOC:signaling, GOC:TermGenie] +synonym: "regulation of PKC" RELATED [GOC:TermGenie] +synonym: "regulation of PKC activity" EXACT [GOC:TermGenie] +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004697 ! protein kinase C activity +relationship: regulates GO:0004697 ! protein kinase C activity +created_by: bf +creation_date: 2012-01-11T03:50:47Z + +[Term] +id: GO:1900020 +name: positive regulation of protein kinase C activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein kinase C activity." [GOC:signaling, GOC:TermGenie] +synonym: "positive regulation of PKC" RELATED [GOC:TermGenie] +synonym: "positive regulation of PKC activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PKC" RELATED [GOC:TermGenie] +synonym: "up regulation of PKC activity" EXACT [GOC:TermGenie] +is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity +is_a: GO:1900019 ! regulation of protein kinase C activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004697 ! protein kinase C activity +relationship: positively_regulates GO:0004697 ! protein kinase C activity +created_by: bf +creation_date: 2012-01-11T03:50:55Z + +[Term] +id: GO:1900022 +name: regulation of D-erythro-sphingosine kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity." [GOC:signaling, GOC:TermGenie] +synonym: "regulation of sphingosine kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017050 ! D-erythro-sphingosine kinase activity +relationship: regulates GO:0017050 ! D-erythro-sphingosine kinase activity +created_by: bf +creation_date: 2012-01-11T04:30:29Z + +[Term] +id: GO:1900023 +name: positive regulation of D-erythro-sphingosine kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity." [GOC:signaling, GOC:TermGenie] +synonym: "positive regulation of sphingosine kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of D-erythro-sphingosine kinase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of sphingosine kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0033674 ! positive regulation of kinase activity +is_a: GO:1900022 ! regulation of D-erythro-sphingosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017050 ! D-erythro-sphingosine kinase activity +relationship: positively_regulates GO:0017050 ! D-erythro-sphingosine kinase activity +created_by: bf +creation_date: 2012-01-11T04:30:33Z + +[Term] +id: GO:1900024 +name: regulation of substrate adhesion-dependent cell spreading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of cell spreading during cell substrate adhesion" EXACT [GOC:TermGenie] +synonym: "regulation of substrate adhesion dependent cell spreading" EXACT [GOC:TermGenie] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0010810 ! regulation of cell-substrate adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034446 ! substrate adhesion-dependent cell spreading +relationship: regulates GO:0034446 ! substrate adhesion-dependent cell spreading +created_by: yaf +creation_date: 2012-01-12T05:00:39Z + +[Term] +id: GO:1900025 +name: negative regulation of substrate adhesion-dependent cell spreading +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of cell spreading during cell substrate adhesion" EXACT [GOC:TermGenie] +synonym: "down regulation of substrate adhesion dependent cell spreading" EXACT [GOC:TermGenie] +synonym: "down regulation of substrate adhesion-dependent cell spreading" RELATED [GOC:TermGenie] +synonym: "negative regulation of cell spreading during cell substrate adhesion" EXACT [GOC:TermGenie] +synonym: "negative regulation of substrate adhesion dependent cell spreading" EXACT [GOC:TermGenie] +is_a: GO:0010771 ! negative regulation of cell morphogenesis involved in differentiation +is_a: GO:0010812 ! negative regulation of cell-substrate adhesion +is_a: GO:1900024 ! regulation of substrate adhesion-dependent cell spreading +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034446 ! substrate adhesion-dependent cell spreading +relationship: negatively_regulates GO:0034446 ! substrate adhesion-dependent cell spreading +created_by: yaf +creation_date: 2012-01-12T05:00:43Z + +[Term] +id: GO:1900026 +name: positive regulation of substrate adhesion-dependent cell spreading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading." [GOC:TermGenie, GOC:yaf] +synonym: "positive regulation of cell spreading during cell substrate adhesion" EXACT [GOC:TermGenie] +synonym: "positive regulation of substrate adhesion dependent cell spreading" EXACT [GOC:TermGenie] +synonym: "up regulation of cell spreading during cell substrate adhesion" EXACT [GOC:TermGenie] +synonym: "up regulation of substrate adhesion dependent cell spreading" EXACT [GOC:TermGenie] +synonym: "up regulation of substrate adhesion-dependent cell spreading" RELATED [GOC:TermGenie] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0010811 ! positive regulation of cell-substrate adhesion +is_a: GO:1900024 ! regulation of substrate adhesion-dependent cell spreading +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034446 ! substrate adhesion-dependent cell spreading +relationship: positively_regulates GO:0034446 ! substrate adhesion-dependent cell spreading +created_by: yaf +creation_date: 2012-01-12T05:00:46Z + +[Term] +id: GO:1900027 +name: regulation of ruffle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ruffle assembly." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of membrane ruffle formation" EXACT [GOC:TermGenie] +synonym: "regulation of membrane ruffling" EXACT [GOC:TermGenie] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097178 ! ruffle assembly +relationship: regulates GO:0097178 ! ruffle assembly +created_by: yaf +creation_date: 2012-01-12T05:00:49Z + +[Term] +id: GO:1900028 +name: negative regulation of ruffle assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of membrane ruffle formation" EXACT [GOC:TermGenie] +synonym: "down regulation of membrane ruffling" EXACT [GOC:TermGenie] +synonym: "down regulation of ruffle assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of membrane ruffle formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of membrane ruffling" EXACT [GOC:TermGenie] +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:1900027 ! regulation of ruffle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097178 ! ruffle assembly +relationship: negatively_regulates GO:0097178 ! ruffle assembly +created_by: yaf +creation_date: 2012-01-12T05:00:53Z + +[Term] +id: GO:1900029 +name: positive regulation of ruffle assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ruffle assembly." [GOC:TermGenie, GOC:yaf] +synonym: "positive regulation of membrane ruffle formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of membrane ruffling" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane ruffle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane ruffling" EXACT [GOC:TermGenie] +synonym: "up regulation of ruffle assembly" RELATED [GOC:TermGenie] +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:1900027 ! regulation of ruffle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097178 ! ruffle assembly +relationship: positively_regulates GO:0097178 ! ruffle assembly +created_by: yaf +creation_date: 2012-01-12T05:00:56Z + +[Term] +id: GO:1900030 +name: regulation of pectin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pectin biosynthetic process." [GOC:TermGenie] +synonym: "regulation of pectin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of pectin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of pectin formation" EXACT [GOC:TermGenie] +synonym: "regulation of pectin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045489 ! pectin biosynthetic process +relationship: regulates GO:0045489 ! pectin biosynthetic process +created_by: tb +creation_date: 2012-01-13T02:03:37Z + +[Term] +id: GO:1900031 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling +namespace: biological_process +def: "OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling." [GOC:TermGenie, PMID:9407035, PMID:9407036] +synonym: "global transcription regulation from Pol II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of calcium signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of calcium signalling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signalling" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-01-13T04:09:19Z + +[Term] +id: GO:1900032 +name: regulation of trichome patterning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trichome patterning." [GOC:TermGenie] +synonym: "regulation of trichome distribution" BROAD [GOC:TermGenie] +synonym: "regulation of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "regulation of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "regulation of trichome spacing" EXACT [GOC:TermGenie] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048629 ! trichome patterning +relationship: regulates GO:0048629 ! trichome patterning +created_by: tb +creation_date: 2012-01-13T11:10:46Z + +[Term] +id: GO:1900033 +name: negative regulation of trichome patterning +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning." [GOC:TermGenie] +synonym: "down regulation of trichome distribution" BROAD [GOC:TermGenie] +synonym: "down regulation of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "down regulation of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "down regulation of trichome patterning" RELATED [GOC:TermGenie] +synonym: "down regulation of trichome spacing" EXACT [GOC:TermGenie] +synonym: "down-regulation of trichome distribution" BROAD [GOC:TermGenie] +synonym: "down-regulation of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "down-regulation of trichome patterning" RELATED [GOC:TermGenie] +synonym: "down-regulation of trichome spacing" EXACT [GOC:TermGenie] +synonym: "downregulation of trichome distribution" BROAD [GOC:TermGenie] +synonym: "downregulation of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "downregulation of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "downregulation of trichome patterning" RELATED [GOC:TermGenie] +synonym: "downregulation of trichome spacing" EXACT [GOC:TermGenie] +synonym: "inhibition of trichome distribution" BROAD [GOC:TermGenie] +synonym: "inhibition of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "inhibition of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "inhibition of trichome patterning" RELATED [GOC:TermGenie] +synonym: "inhibition of trichome spacing" EXACT [GOC:TermGenie] +synonym: "negative regulation of trichome distribution" BROAD [GOC:TermGenie] +synonym: "negative regulation of trichome pattern biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of trichome pattern formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of trichome pattern specification" RELATED [GOC:TermGenie] +synonym: "negative regulation of trichome spacing" EXACT [GOC:TermGenie] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1900032 ! regulation of trichome patterning +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048629 ! trichome patterning +relationship: negatively_regulates GO:0048629 ! trichome patterning +created_by: tb +creation_date: 2012-01-13T11:10:50Z + +[Term] +id: GO:1900034 +name: regulation of cellular response to heat +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to heat." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034605 ! cellular response to heat +relationship: regulates GO:0034605 ! cellular response to heat +created_by: yaf +creation_date: 2012-01-17T09:27:40Z + +[Term] +id: GO:1900035 +name: negative regulation of cellular response to heat +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "down regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "inhibition of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900034 ! regulation of cellular response to heat +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034605 ! cellular response to heat +relationship: negatively_regulates GO:0034605 ! cellular response to heat +created_by: yaf +creation_date: 2012-01-17T09:27:44Z + +[Term] +id: GO:1900036 +name: positive regulation of cellular response to heat +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to heat." [GOC:TermGenie, GOC:yaf] +synonym: "activation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "activation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "up regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "up-regulation of cellular response to heat stress" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to heat" RELATED [GOC:TermGenie] +synonym: "upregulation of cellular response to heat stress" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900034 ! regulation of cellular response to heat +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034605 ! cellular response to heat +relationship: positively_regulates GO:0034605 ! cellular response to heat +created_by: yaf +creation_date: 2012-01-17T09:27:47Z + +[Term] +id: GO:1900037 +name: regulation of cellular response to hypoxia +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to hypoxia." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071456 ! cellular response to hypoxia +relationship: regulates GO:0071456 ! cellular response to hypoxia +created_by: yaf +creation_date: 2012-01-17T09:29:03Z + +[Term] +id: GO:1900038 +name: negative regulation of cellular response to hypoxia +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "down regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "inhibition of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900037 ! regulation of cellular response to hypoxia +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071456 ! cellular response to hypoxia +relationship: negatively_regulates GO:0071456 ! cellular response to hypoxia +created_by: yaf +creation_date: 2012-01-17T09:29:16Z + +[Term] +id: GO:1900039 +name: positive regulation of cellular response to hypoxia +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia." [GOC:TermGenie, GOC:yaf] +synonym: "activation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "activation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "activation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "up regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "up-regulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to hypoxia" RELATED [GOC:TermGenie] +synonym: "upregulation of cellular response to hypoxic stress" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to lowered oxygen tension" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900037 ! regulation of cellular response to hypoxia +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071456 ! cellular response to hypoxia +relationship: positively_regulates GO:0071456 ! cellular response to hypoxia +created_by: yaf +creation_date: 2012-01-17T09:29:19Z + +[Term] +id: GO:1900040 +name: regulation of interleukin-2 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-2 secretion." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of IL-2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032663 ! regulation of interleukin-2 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070970 ! interleukin-2 secretion +relationship: regulates GO:0070970 ! interleukin-2 secretion +created_by: yaf +creation_date: 2012-01-17T11:20:57Z + +[Term] +id: GO:1900041 +name: negative regulation of interleukin-2 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2 secretion." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "down-regulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "downregulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "inhibition of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "negative regulation of IL-2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032703 ! negative regulation of interleukin-2 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1900040 ! regulation of interleukin-2 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070970 ! interleukin-2 secretion +relationship: negatively_regulates GO:0070970 ! interleukin-2 secretion +created_by: yaf +creation_date: 2012-01-17T11:21:06Z + +[Term] +id: GO:1900042 +name: positive regulation of interleukin-2 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-2 secretion." [GOC:TermGenie, GOC:yaf] +synonym: "activation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "activation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "positive regulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "up-regulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +synonym: "upregulation of IL-2 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-2 secretion" RELATED [GOC:TermGenie] +is_a: GO:0032743 ! positive regulation of interleukin-2 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1900040 ! regulation of interleukin-2 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070970 ! interleukin-2 secretion +relationship: positively_regulates GO:0070970 ! interleukin-2 secretion +created_by: yaf +creation_date: 2012-01-17T11:21:10Z + +[Term] +id: GO:1900043 +name: obsolete leptin-mediated signaling pathway involved in negative regulation of appetite +namespace: biological_process +def: "OBSOLETE. Any leptin-mediated signaling pathway that is involved in negative regulation of appetite." [GOC:BHF, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "adipocytokine signaling pathway of appetite suppression" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of down regulation of appetite" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of down-regulation of appetite" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of downregulation of appetite" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of inhibition of appetite" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of negative regulation of appetite" RELATED [GOC:TermGenie] +synonym: "adipocytokine signaling pathway of negative regulation of hunger" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway involved in negative regulation of appetite" EXACT [] +synonym: "leptin-mediated signaling pathway of appetite suppression" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of down regulation of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of down-regulation of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of downregulation of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of inhibition of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of negative regulation of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signaling pathway of negative regulation of hunger" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of appetite suppression" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of down regulation of appetite" EXACT [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of down-regulation of appetite" EXACT [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of downregulation of appetite" EXACT [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of inhibition of appetite" NARROW [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of negative regulation of appetite" RELATED [GOC:TermGenie] +synonym: "leptin-mediated signalling pathway of negative regulation of hunger" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: vk +creation_date: 2012-01-19T11:10:22Z + +[Term] +id: GO:1900044 +name: regulation of protein K63-linked ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination." [GOC:TermGenie] +synonym: "regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +is_a: GO:1902914 ! regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070534 ! protein K63-linked ubiquitination +relationship: regulates GO:0070534 ! protein K63-linked ubiquitination +created_by: bf +creation_date: 2012-01-19T11:44:37Z + +[Term] +id: GO:1900045 +name: negative regulation of protein K63-linked ubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination." [GOC:TermGenie] +synonym: "down regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein K63-linked ubiquitination" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein K63-linked ubiquitination" RELATED [GOC:TermGenie] +synonym: "downregulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein K63-linked ubiquitination" RELATED [GOC:TermGenie] +synonym: "inhibition of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "inhibition of protein K63-linked ubiquitination" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +is_a: GO:1900044 ! regulation of protein K63-linked ubiquitination +is_a: GO:1902915 ! negative regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070534 ! protein K63-linked ubiquitination +relationship: negatively_regulates GO:0070534 ! protein K63-linked ubiquitination +created_by: bf +creation_date: 2012-01-19T11:44:41Z + +[Term] +id: GO:1900046 +name: regulation of hemostasis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hemostasis." [GOC:TermGenie] +is_a: GO:0050789 ! regulation of biological process +is_a: GO:0050878 ! regulation of body fluid levels +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007599 ! hemostasis +relationship: regulates GO:0007599 ! hemostasis +created_by: jl +creation_date: 2012-01-19T03:23:38Z + +[Term] +id: GO:1900047 +name: negative regulation of hemostasis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis." [GOC:TermGenie] +synonym: "down regulation of hemostasis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemostasis" EXACT [GOC:TermGenie] +synonym: "downregulation of hemostasis" EXACT [GOC:TermGenie] +synonym: "inhibition of hemostasis" NARROW [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1900046 ! regulation of hemostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007599 ! hemostasis +relationship: negatively_regulates GO:0007599 ! hemostasis +created_by: jl +creation_date: 2012-01-19T03:23:42Z + +[Term] +id: GO:1900048 +name: positive regulation of hemostasis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hemostasis." [GOC:TermGenie] +synonym: "activation of hemostasis" NARROW [GOC:TermGenie] +synonym: "up regulation of hemostasis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemostasis" EXACT [GOC:TermGenie] +synonym: "upregulation of hemostasis" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1900046 ! regulation of hemostasis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007599 ! hemostasis +relationship: positively_regulates GO:0007599 ! hemostasis +created_by: jl +creation_date: 2012-01-19T03:23:45Z + +[Term] +id: GO:1900049 +name: regulation of histone exchange +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone exchange." [GOC:TermGenie, PMID:20332092] +synonym: "regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "regulation of histone displacement" EXACT [GOC:TermGenie] +synonym: "regulation of histone replacement" EXACT [GOC:TermGenie] +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043486 ! histone exchange +relationship: regulates GO:0043486 ! histone exchange +created_by: se +creation_date: 2012-01-19T10:59:02Z + +[Term] +id: GO:1900050 +name: negative regulation of histone exchange +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange." [GOC:TermGenie, PMID:20332092] +synonym: "down regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "down regulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "down regulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "down-regulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "down-regulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "downregulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "downregulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "downregulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "inhibition of histone chaperone" RELATED [GOC:TermGenie] +synonym: "inhibition of histone exchange" RELATED [GOC:TermGenie] +synonym: "inhibition of histone replacement" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "negative regulation of histone replacement" EXACT [GOC:TermGenie] +is_a: GO:1900049 ! regulation of histone exchange +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043486 ! histone exchange +relationship: negatively_regulates GO:0043486 ! histone exchange +created_by: se +creation_date: 2012-01-19T10:59:09Z + +[Term] +id: GO:1900051 +name: positive regulation of histone exchange +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone exchange." [GOC:TermGenie, PMID:20332092] +synonym: "activation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "activation of histone exchange" RELATED [GOC:TermGenie] +synonym: "activation of histone replacement" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "positive regulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "up regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "up regulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "up regulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "up-regulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "up-regulation of histone replacement" EXACT [GOC:TermGenie] +synonym: "upregulation of histone chaperone" RELATED [GOC:TermGenie] +synonym: "upregulation of histone exchange" RELATED [GOC:TermGenie] +synonym: "upregulation of histone replacement" EXACT [GOC:TermGenie] +is_a: GO:1900049 ! regulation of histone exchange +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043486 ! histone exchange +relationship: positively_regulates GO:0043486 ! histone exchange +created_by: se +creation_date: 2012-01-19T10:59:12Z + +[Term] +id: GO:1900052 +name: regulation of retinoic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002138 ! retinoic acid biosynthetic process +relationship: regulates GO:0002138 ! retinoic acid biosynthetic process +created_by: yaf +creation_date: 2012-01-20T09:55:45Z + +[Term] +id: GO:1900053 +name: negative regulation of retinoic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1900052 ! regulation of retinoic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002138 ! retinoic acid biosynthetic process +relationship: negatively_regulates GO:0002138 ! retinoic acid biosynthetic process +created_by: yaf +creation_date: 2012-01-20T09:55:49Z + +[Term] +id: GO:1900054 +name: positive regulation of retinoic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "activation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "activation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of retinoic acid anabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of retinoic acid biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046136 ! positive regulation of vitamin metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1900052 ! regulation of retinoic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002138 ! retinoic acid biosynthetic process +relationship: positively_regulates GO:0002138 ! retinoic acid biosynthetic process +created_by: yaf +creation_date: 2012-01-20T09:55:52Z + +[Term] +id: GO:1900055 +name: regulation of leaf senescence +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leaf senescence." [GOC:TermGenie] +is_a: GO:2000024 ! regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010150 ! leaf senescence +relationship: regulates GO:0010150 ! leaf senescence +created_by: tb +creation_date: 2012-01-24T11:51:24Z + +[Term] +id: GO:1900056 +name: negative regulation of leaf senescence +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence." [GOC:TermGenie] +synonym: "down regulation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "down-regulation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "downregulation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "inhibition of leaf senescence" RELATED [GOC:TermGenie] +is_a: GO:1900055 ! regulation of leaf senescence +is_a: GO:1905622 ! negative regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010150 ! leaf senescence +relationship: negatively_regulates GO:0010150 ! leaf senescence +created_by: tb +creation_date: 2012-01-24T11:51:32Z + +[Term] +id: GO:1900057 +name: positive regulation of leaf senescence +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leaf senescence." [GOC:TermGenie] +synonym: "activation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "up regulation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "up-regulation of leaf senescence" RELATED [GOC:TermGenie] +synonym: "upregulation of leaf senescence" RELATED [GOC:TermGenie] +is_a: GO:1900055 ! regulation of leaf senescence +is_a: GO:1905623 ! positive regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010150 ! leaf senescence +relationship: positively_regulates GO:0010150 ! leaf senescence +created_by: tb +creation_date: 2012-01-24T11:51:36Z + +[Term] +id: GO:1900058 +name: regulation of sulfate assimilation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sulfate assimilation." [GOC:TermGenie, PMID:7601277, PMID:7891681] +synonym: "regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "regulation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +is_a: GO:0042762 ! regulation of sulfur metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000103 ! sulfate assimilation +relationship: regulates GO:0000103 ! sulfate assimilation +created_by: dph +creation_date: 2012-01-25T03:14:40Z + +[Term] +id: GO:1900059 +name: positive regulation of sulfate assimilation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sulfate assimilation." [GOC:TermGenie, PMID:7601277, PMID:7891681] +synonym: "activation of sulfate assimilation" RELATED [GOC:TermGenie] +synonym: "activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "activation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "positive regulation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "up regulation of sulfate assimilation" RELATED [GOC:TermGenie] +synonym: "up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "up regulation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "up-regulation of sulfate assimilation" RELATED [GOC:TermGenie] +synonym: "up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "up-regulation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "upregulation of sulfate assimilation" RELATED [GOC:TermGenie] +synonym: "upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +synonym: "upregulation of sulphate assimilation" EXACT [GOC:TermGenie] +synonym: "upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor" NARROW [GOC:TermGenie] +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900058 ! regulation of sulfate assimilation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000103 ! sulfate assimilation +relationship: positively_regulates GO:0000103 ! sulfate assimilation +created_by: dph +creation_date: 2012-01-25T03:14:47Z + +[Term] +id: GO:1900060 +name: negative regulation of ceramide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process." [GOC:TermGenie, PMID:15302821] +synonym: "down regulation of ceramide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ceramide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ceramide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of ceramide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ceramide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ceramide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ceramide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ceramide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of ceramide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ceramide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ceramide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ceramide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ceramide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of ceramide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ceramide synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ceramide anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of ceramide biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ceramide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of ceramide formation" EXACT [GOC:TermGenie] +synonym: "inhibition of ceramide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ceramide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ceramide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ceramide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ceramide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0090155 ! negative regulation of sphingolipid biosynthetic process +is_a: GO:2000303 ! regulation of ceramide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046513 ! ceramide biosynthetic process +relationship: negatively_regulates GO:0046513 ! ceramide biosynthetic process +created_by: dph +creation_date: 2012-01-25T03:18:07Z + +[Term] +id: GO:1900061 +name: obsolete positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling +namespace: biological_process +def: "OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling." [GOC:TermGenie, PMID:9407035, PMID:9407036] +comment: This term was made obsolete because it represents a GO-CAM model. +synonym: "activation of global transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter of calcium ion signaling" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter of calcium signaling" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter of calcium signalling" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter of calcium-mediated signaling" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter of calcium-mediated signalling" NARROW [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter of calcium ion signaling" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter of calcium signaling" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter of calcium signalling" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter of calcium ion signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter of calcium signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter of calcium signalling" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter of calcium ion signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter of calcium signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter of calcium signalling" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter of calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter of calcium-mediated signalling" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dph +creation_date: 2012-01-26T01:42:53Z + +[Term] +id: GO:1900062 +name: regulation of replicative cell aging +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of replicative cell aging." [GOC:TermGenie, PMID:17914901] +synonym: "regulation of replicative cell ageing" EXACT [GOC:TermGenie] +is_a: GO:0090342 ! regulation of cell aging +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001302 ! replicative cell aging +relationship: regulates GO:0001302 ! replicative cell aging +created_by: dph +creation_date: 2012-01-26T01:46:47Z + +[Term] +id: GO:1900063 +name: regulation of peroxisome organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peroxisome organization." [GOC:TermGenie, PMID:7500953] +synonym: "regulation of peroxisome organisation" EXACT [GOC:TermGenie] +synonym: "regulation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007031 ! peroxisome organization +relationship: regulates GO:0007031 ! peroxisome organization +created_by: dph +creation_date: 2012-01-26T01:49:05Z + +[Term] +id: GO:1900064 +name: positive regulation of peroxisome organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peroxisome organization." [GOC:TermGenie, PMID:7500953] +synonym: "activation of peroxisome organisation" NARROW [GOC:TermGenie] +synonym: "activation of peroxisome organization" NARROW [GOC:TermGenie] +synonym: "activation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "activation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of peroxisome organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of peroxisome organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of peroxisome organization" RELATED [GOC:TermGenie] +synonym: "up regulation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of peroxisome organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of peroxisome organization" RELATED [GOC:TermGenie] +synonym: "up-regulation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of peroxisome organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of peroxisome organization" RELATED [GOC:TermGenie] +synonym: "upregulation of peroxisome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of peroxisome-assembly ATPase activity" RELATED [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1900063 ! regulation of peroxisome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007031 ! peroxisome organization +relationship: positively_regulates GO:0007031 ! peroxisome organization +created_by: dph +creation_date: 2012-01-26T01:49:09Z + +[Term] +id: GO:1900065 +name: regulation of ethanol catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ethanol catabolic process." [GOC:TermGenie, PMID:10608811, PMID:7760841] +synonym: "regulation of ethanol breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of ethanol catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ethanol degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006068 ! ethanol catabolic process +relationship: regulates GO:0006068 ! ethanol catabolic process +created_by: dph +creation_date: 2012-01-26T01:51:40Z + +[Term] +id: GO:1900066 +name: positive regulation of ethanol catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ethanol catabolic process." [GOC:TermGenie, PMID:10608811, PMID:7760841] +synonym: "activation of ethanol breakdown" NARROW [GOC:TermGenie] +synonym: "activation of ethanol catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ethanol catabolism" NARROW [GOC:TermGenie] +synonym: "activation of ethanol degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ethanol breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of ethanol catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ethanol degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of ethanol breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of ethanol catabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of ethanol catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ethanol degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ethanol breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of ethanol catabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of ethanol catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ethanol degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of ethanol breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of ethanol catabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of ethanol catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ethanol degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900065 ! regulation of ethanol catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006068 ! ethanol catabolic process +relationship: positively_regulates GO:0006068 ! ethanol catabolic process +created_by: dph +creation_date: 2012-01-26T01:51:44Z + +[Term] +id: GO:1900067 +name: regulation of cellular response to alkaline pH +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to alkalinity." [GOC:dgf, GOC:TermGenie, PMID:12509465, PMID:17023428] +synonym: "regulation of cellular response to alkalinity" BROAD [] +synonym: "regulation of cellular response to basic pH" EXACT [GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071469 ! cellular response to alkaline pH +relationship: regulates GO:0071469 ! cellular response to alkaline pH +created_by: pr +creation_date: 2012-01-26T02:34:59Z + +[Term] +id: GO:1900068 +name: negative regulation of cellular response to alkaline pH +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity." [GOC:dgf, GOC:TermGenie, PMID:12509465, PMID:17023428] +synonym: "down regulation of cellular response to alkaline pH" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to alkalinity" RELATED [GOC:TermGenie] +synonym: "down regulation of cellular response to basic pH" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to alkaline pH" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to alkalinity" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to basic pH" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to alkaline pH" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to alkalinity" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to basic pH" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to alkaline pH" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to alkalinity" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to basic pH" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to alkalinity" BROAD [] +synonym: "negative regulation of cellular response to basic pH" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900067 ! regulation of cellular response to alkaline pH +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071469 ! cellular response to alkaline pH +relationship: negatively_regulates GO:0071469 ! cellular response to alkaline pH +created_by: pr +creation_date: 2012-01-26T02:35:03Z + +[Term] +id: GO:1900069 +name: regulation of cellular hyperosmotic salinity response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response." [GOC:dgf, GOC:TermGenie, PMID:16278455] +synonym: "regulation of cellular response to hyperosmotic salt stress" EXACT [GOC:TermGenie] +is_a: GO:0106049 ! regulation of cellular response to osmotic stress +is_a: GO:1901000 ! regulation of response to salt stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071475 ! cellular hyperosmotic salinity response +relationship: regulates GO:0071475 ! cellular hyperosmotic salinity response +created_by: pr +creation_date: 2012-01-26T02:45:39Z + +[Term] +id: GO:1900070 +name: negative regulation of cellular hyperosmotic salinity response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response." [GOC:dgf, GOC:TermGenie, PMID:16278455] +synonym: "down regulation of cellular hyperosmotic salinity response" RELATED [GOC:TermGenie] +synonym: "down regulation of cellular response to hyperosmotic salt stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular hyperosmotic salinity response" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to hyperosmotic salt stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular hyperosmotic salinity response" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to hyperosmotic salt stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular hyperosmotic salinity response" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to hyperosmotic salt stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to hyperosmotic salt stress" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1900069 ! regulation of cellular hyperosmotic salinity response +is_a: GO:1901001 ! negative regulation of response to salt stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071475 ! cellular hyperosmotic salinity response +relationship: negatively_regulates GO:0071475 ! cellular hyperosmotic salinity response +created_by: pr +creation_date: 2012-01-26T02:45:43Z + +[Term] +id: GO:1900071 +name: regulation of sulfite transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sulfite transport." [GOC:TermGenie, PMID:10234785, PMID:10870099] +synonym: "regulation of sulphite transport" EXACT [GOC:TermGenie] +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000316 ! sulfite transport +relationship: regulates GO:0000316 ! sulfite transport +created_by: dph +creation_date: 2012-01-26T08:41:10Z + +[Term] +id: GO:1900072 +name: positive regulation of sulfite transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sulfite transport." [GOC:TermGenie, PMID:10234785, PMID:10870099] +synonym: "activation of sulfite transport" NARROW [GOC:TermGenie] +synonym: "activation of sulphite transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of sulphite transport" EXACT [GOC:TermGenie] +synonym: "up regulation of sulfite transport" RELATED [GOC:TermGenie] +synonym: "up regulation of sulphite transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of sulfite transport" RELATED [GOC:TermGenie] +synonym: "up-regulation of sulphite transport" EXACT [GOC:TermGenie] +synonym: "upregulation of sulfite transport" RELATED [GOC:TermGenie] +synonym: "upregulation of sulphite transport" EXACT [GOC:TermGenie] +is_a: GO:1900071 ! regulation of sulfite transport +is_a: GO:1903793 ! positive regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000316 ! sulfite transport +relationship: positively_regulates GO:0000316 ! sulfite transport +created_by: dph +creation_date: 2012-01-26T08:41:16Z + +[Term] +id: GO:1900073 +name: regulation of neuromuscular synaptic transmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] +is_a: GO:0050804 ! modulation of chemical synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007274 ! neuromuscular synaptic transmission +relationship: regulates GO:0007274 ! neuromuscular synaptic transmission +created_by: kmv +creation_date: 2012-01-26T10:14:10Z + +[Term] +id: GO:1900074 +name: negative regulation of neuromuscular synaptic transmission +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] +synonym: "down regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "down-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "downregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "inhibition of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +is_a: GO:0050805 ! negative regulation of synaptic transmission +is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission +relationship: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission +created_by: kmv +creation_date: 2012-01-26T10:14:18Z + +[Term] +id: GO:1900075 +name: positive regulation of neuromuscular synaptic transmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] +synonym: "activation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "up regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "up-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +synonym: "upregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007274 ! neuromuscular synaptic transmission +relationship: positively_regulates GO:0007274 ! neuromuscular synaptic transmission +created_by: kmv +creation_date: 2012-01-26T10:14:22Z + +[Term] +id: GO:1900076 +name: regulation of cellular response to insulin stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032869 ! cellular response to insulin stimulus +relationship: regulates GO:0032869 ! cellular response to insulin stimulus +created_by: yaf +creation_date: 2012-01-31T11:22:22Z + +[Term] +id: GO:1900077 +name: negative regulation of cellular response to insulin stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to insulin stimulus" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900076 ! regulation of cellular response to insulin stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032869 ! cellular response to insulin stimulus +relationship: negatively_regulates GO:0032869 ! cellular response to insulin stimulus +created_by: yaf +creation_date: 2012-01-31T11:23:15Z + +[Term] +id: GO:1900078 +name: positive regulation of cellular response to insulin stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus." [GOC:TermGenie, GOC:yaf] +synonym: "activation of cellular response to insulin stimulus" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to insulin stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900076 ! regulation of cellular response to insulin stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032869 ! cellular response to insulin stimulus +relationship: positively_regulates GO:0032869 ! cellular response to insulin stimulus +created_by: yaf +creation_date: 2012-01-31T11:24:30Z + +[Term] +id: GO:1900079 +name: regulation of arginine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arginine biosynthetic process." [GOC:dgf, GOC:TermGenie] +synonym: "regulation of arginine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of arginine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of arginine formation" EXACT [GOC:TermGenie] +synonym: "regulation of arginine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0000821 ! regulation of arginine metabolic process +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006526 ! arginine biosynthetic process +relationship: regulates GO:0006526 ! arginine biosynthetic process +created_by: pr +creation_date: 2012-02-01T03:57:36Z + +[Term] +id: GO:1900080 +name: positive regulation of arginine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process." [GOC:dgf, GOC:TermGenie] +synonym: "activation of arginine anabolism" NARROW [GOC:TermGenie] +synonym: "activation of arginine biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of arginine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of arginine formation" NARROW [GOC:TermGenie] +synonym: "activation of arginine synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of arginine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900079 ! regulation of arginine biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006526 ! arginine biosynthetic process +relationship: positively_regulates GO:0006526 ! arginine biosynthetic process +created_by: pr +creation_date: 2012-02-01T03:57:41Z + +[Term] +id: GO:1900081 +name: regulation of arginine catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arginine catabolic process." [GOC:dgf, GOC:TermGenie] +synonym: "regulation of arginine breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of arginine catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of arginine degradation" EXACT [GOC:TermGenie] +is_a: GO:0000821 ! regulation of arginine metabolic process +is_a: GO:0033241 ! regulation of cellular amine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006527 ! arginine catabolic process +relationship: regulates GO:0006527 ! arginine catabolic process +created_by: pr +creation_date: 2012-02-01T04:04:39Z + +[Term] +id: GO:1900082 +name: negative regulation of arginine catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process." [GOC:dgf, GOC:TermGenie] +synonym: "down regulation of arginine breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of arginine catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of arginine catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of arginine degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of arginine breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of arginine catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of arginine catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of arginine degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of arginine breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of arginine catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of arginine catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of arginine degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of arginine breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of arginine catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of arginine catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of arginine degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of arginine breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of arginine catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of arginine degradation" EXACT [GOC:TermGenie] +is_a: GO:0033242 ! negative regulation of cellular amine catabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:1900081 ! regulation of arginine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006527 ! arginine catabolic process +relationship: negatively_regulates GO:0006527 ! arginine catabolic process +created_by: pr +creation_date: 2012-02-01T04:04:45Z + +[Term] +id: GO:1900083 +name: obsolete regulation of Sertoli cell proliferation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of Sertoli cell proliferation." [GOC:pr, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of Sertoli cell proliferation" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2012-02-02T03:10:50Z + +[Term] +id: GO:1900084 +name: regulation of peptidyl-tyrosine autophosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] +synonym: "regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0031952 ! regulation of protein autophosphorylation +is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +relationship: regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +created_by: bf +creation_date: 2012-02-03T10:17:07Z + +[Term] +id: GO:1900085 +name: negative regulation of peptidyl-tyrosine autophosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] +synonym: "down regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "down regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "down-regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "downregulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidyl-tyrosine autophosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine autophosphorylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0031953 ! negative regulation of protein autophosphorylation +is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation +is_a: GO:1900084 ! regulation of peptidyl-tyrosine autophosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +relationship: negatively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +created_by: bf +creation_date: 2012-02-03T10:17:12Z + +[Term] +id: GO:1900086 +name: positive regulation of peptidyl-tyrosine autophosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] +synonym: "activation of peptidyl-tyrosine autophosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of tyrosine autophosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "up regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "up-regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] +synonym: "upregulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0031954 ! positive regulation of protein autophosphorylation +is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation +is_a: GO:1900084 ! regulation of peptidyl-tyrosine autophosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +relationship: positively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation +created_by: bf +creation_date: 2012-02-03T10:17:15Z + +[Term] +id: GO:1900087 +name: positive regulation of G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] +synonym: "activation of G1/S transition of mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "up regulation of G1/S transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of G1/S transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of G1/S transition of mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:1901992 ! positive regulation of mitotic cell cycle phase transition +is_a: GO:1902808 ! positive regulation of cell cycle G1/S phase transition +is_a: GO:2000045 ! regulation of G1/S transition of mitotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle +relationship: positively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: rph +creation_date: 2012-02-08T12:24:39Z + +[Term] +id: GO:1900088 +name: regulation of inositol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inositol biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006021 ! inositol biosynthetic process +relationship: regulates GO:0006021 ! inositol biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:27:11Z + +[Term] +id: GO:1900089 +name: negative regulation of inositol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "down regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of inositol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900088 ! regulation of inositol biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006021 ! inositol biosynthetic process +relationship: negatively_regulates GO:0006021 ! inositol biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:27:28Z + +[Term] +id: GO:1900090 +name: positive regulation of inositol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "activation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of inositol formation" EXACT [GOC:TermGenie] +synonym: "activation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "activation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of myo-inositol biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of myo-inositol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of vitamin Bh biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin Bh biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900088 ! regulation of inositol biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006021 ! inositol biosynthetic process +relationship: positively_regulates GO:0006021 ! inositol biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:27:31Z + +[Term] +id: GO:1900091 +name: regulation of raffinose biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of raffinose biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "regulation of raffinose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +is_a: GO:0080091 ! regulation of raffinose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033529 ! raffinose biosynthetic process +relationship: regulates GO:0033529 ! raffinose biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:31:54Z + +[Term] +id: GO:1900092 +name: negative regulation of raffinose biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "down regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "down regulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "downregulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of raffinose biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of raffinose formation" EXACT [GOC:TermGenie] +synonym: "inhibition of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of raffinose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:1900091 ! regulation of raffinose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033529 ! raffinose biosynthetic process +relationship: negatively_regulates GO:0033529 ! raffinose biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:31:58Z + +[Term] +id: GO:1900093 +name: positive regulation of raffinose biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process." [GOC:TermGenie, PMID:22307851] +synonym: "activation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "activation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of raffinose biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "activation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "up regulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of raffinose synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of raffinose anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of raffinose biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of raffinose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of raffinose formation" EXACT [GOC:TermGenie] +synonym: "upregulation of raffinose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:1900091 ! regulation of raffinose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033529 ! raffinose biosynthetic process +relationship: positively_regulates GO:0033529 ! raffinose biosynthetic process +created_by: dhl +creation_date: 2012-02-08T06:32:01Z + +[Term] +id: GO:1900094 +name: regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry +namespace: biological_process +def: "Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry." [GOC:BHF, GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of determination of left/right asymmetry" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter of determination of left/right symmetry" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right asymmetry" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right symmetry" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of determination of left/right asymmetry" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter of determination of left/right symmetry" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of determination of left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter of determination of left/right symmetry" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of determination of left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter of determination of left/right symmetry" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of determination of left/right asymmetry" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global of determination of left/right symmetry" RELATED [GOC:TermGenie] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0007368 ! determination of left/right symmetry +relationship: part_of GO:0007368 ! determination of left/right symmetry +created_by: vk +creation_date: 2012-02-14T10:58:20Z + +[Term] +id: GO:1900095 +name: regulation of dosage compensation by inactivation of X chromosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome." [GOC:mr, GOC:TermGenie, PMID:20622855, Wikipedia:XY_sex-determination_system] +synonym: "regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +is_a: GO:0010468 ! regulation of gene expression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +relationship: regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +property_value: RO:0002161 NCBITaxon:8782 +created_by: hjd +creation_date: 2012-02-14T07:29:45Z + +[Term] +id: GO:1900096 +name: negative regulation of dosage compensation by inactivation of X chromosome +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome." [GOC:TermGenie] +synonym: "down regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "down regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "down regulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "down regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "down-regulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "downregulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "downregulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "downregulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "downregulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "inhibition of Barr body formation" RELATED [GOC:TermGenie] +synonym: "inhibition of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "inhibition of dosage compensation, by inactivation of X chromosome" NARROW [GOC:TermGenie] +synonym: "inhibition of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "negative regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1900095 ! regulation of dosage compensation by inactivation of X chromosome +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +relationship: negatively_regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: hjd +creation_date: 2012-02-14T07:29:49Z + +[Term] +id: GO:1900097 +name: positive regulation of dosage compensation by inactivation of X chromosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome." [GOC:TermGenie] +synonym: "activation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "activation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "activation of dosage compensation, by inactivation of X chromosome" NARROW [GOC:TermGenie] +synonym: "activation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "positive regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "up regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "up regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "up regulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "up regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "up-regulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of X chromosome inactivation" EXACT [GOC:TermGenie] +synonym: "upregulation of Barr body formation" RELATED [GOC:TermGenie] +synonym: "upregulation of chromosome inactivation" BROAD [GOC:TermGenie] +synonym: "upregulation of dosage compensation, by inactivation of X chromosome" EXACT [GOC:TermGenie] +synonym: "upregulation of X chromosome inactivation" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1900095 ! regulation of dosage compensation by inactivation of X chromosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +relationship: positively_regulates GO:0009048 ! dosage compensation by inactivation of X chromosome +created_by: hjd +creation_date: 2012-02-14T07:29:52Z + +[Term] +id: GO:1900098 +name: regulation of plasma cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plasma cell differentiation." [GOC:TermGenie] +synonym: "regulation of plasma cell development" RELATED [GOC:TermGenie] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0045577 ! regulation of B cell differentiation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002317 ! plasma cell differentiation +relationship: regulates GO:0002317 ! plasma cell differentiation +created_by: bf +creation_date: 2012-02-15T10:46:00Z + +[Term] +id: GO:1900099 +name: negative regulation of plasma cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation." [GOC:TermGenie] +synonym: "down regulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "down regulation of plasma cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "down-regulation of plasma cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "downregulation of plasma cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of plasma cell development" RELATED [GOC:TermGenie] +synonym: "inhibition of plasma cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of plasma cell development" RELATED [GOC:TermGenie] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0045578 ! negative regulation of B cell differentiation +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:1900098 ! regulation of plasma cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002317 ! plasma cell differentiation +relationship: negatively_regulates GO:0002317 ! plasma cell differentiation +created_by: bf +creation_date: 2012-02-15T10:46:05Z + +[Term] +id: GO:1900100 +name: positive regulation of plasma cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plasma cell differentiation." [GOC:TermGenie] +synonym: "activation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "activation of plasma cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "up regulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "up regulation of plasma cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "up-regulation of plasma cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of plasma cell development" RELATED [GOC:TermGenie] +synonym: "upregulation of plasma cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0045579 ! positive regulation of B cell differentiation +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:1900098 ! regulation of plasma cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002317 ! plasma cell differentiation +relationship: positively_regulates GO:0002317 ! plasma cell differentiation +created_by: bf +creation_date: 2012-02-15T10:46:08Z + +[Term] +id: GO:1900101 +name: regulation of endoplasmic reticulum unfolded protein response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response." [GOC:TermGenie] +synonym: "regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +relationship: regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: ppm +creation_date: 2012-02-15T11:15:27Z + +[Term] +id: GO:1900102 +name: negative regulation of endoplasmic reticulum unfolded protein response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response." [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "down regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "down-regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of erUPR" EXACT [GOC:TermGenie] +synonym: "downregulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "inhibition of erUPR" EXACT [GOC:TermGenie] +synonym: "inhibition of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "negative regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903573 ! negative regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +relationship: negatively_regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: ppm +creation_date: 2012-02-15T11:15:31Z + +[Term] +id: GO:1900103 +name: positive regulation of endoplasmic reticulum unfolded protein response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response." [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "activation of erUPR" EXACT [GOC:TermGenie] +synonym: "activation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "positive regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "positive regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "up regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of erUPR" EXACT [GOC:TermGenie] +synonym: "up-regulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of ER unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of erUPR" EXACT [GOC:TermGenie] +synonym: "upregulation of SREBP-mediated signalling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1905898 ! positive regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +relationship: positively_regulates GO:0030968 ! endoplasmic reticulum unfolded protein response +created_by: ppm +creation_date: 2012-02-15T11:15:35Z + +[Term] +id: GO:1900104 +name: regulation of hyaluranon cable assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hyaluranon cable assembly." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of HA cable assembly" EXACT [GOC:TermGenie] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036118 ! hyaluranon cable assembly +relationship: regulates GO:0036118 ! hyaluranon cable assembly +created_by: yaf +creation_date: 2012-02-16T01:00:41Z + +[Term] +id: GO:1900105 +name: negative regulation of hyaluranon cable assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of hyaluranon cable assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of HA cable assembly" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1900104 ! regulation of hyaluranon cable assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036118 ! hyaluranon cable assembly +relationship: negatively_regulates GO:0036118 ! hyaluranon cable assembly +created_by: yaf +creation_date: 2012-02-16T01:00:50Z + +[Term] +id: GO:1900106 +name: positive regulation of hyaluranon cable assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly." [GOC:TermGenie, GOC:yaf] +synonym: "activation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "activation of hyaluranon cable assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of HA cable assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluranon cable assembly" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1900104 ! regulation of hyaluranon cable assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036118 ! hyaluranon cable assembly +relationship: positively_regulates GO:0036118 ! hyaluranon cable assembly +created_by: yaf +creation_date: 2012-02-16T01:00:54Z + +[Term] +id: GO:1900107 +name: regulation of nodal signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nodal signaling pathway." [GOC:BHF, GOC:TermGenie, GOC:vk] +synonym: "regulation of nodal signaling" EXACT [GOC:TermGenie] +synonym: "regulation of nodal signalling pathway" EXACT [GOC:mah] +is_a: GO:0032925 ! regulation of activin receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038092 ! nodal signaling pathway +relationship: regulates GO:0038092 ! nodal signaling pathway +created_by: bf +creation_date: 2012-02-16T03:34:19Z + +[Term] +id: GO:1900108 +name: negative regulation of nodal signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway." [GOC:BHF, GOC:TermGenie, GOC:vk] +synonym: "down regulation of nodal signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of nodal signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of nodal signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of nodal signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of nodal signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of nodal signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of nodal signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of nodal signalling pathway" EXACT [GOC:mah] +is_a: GO:0032926 ! negative regulation of activin receptor signaling pathway +is_a: GO:1900107 ! regulation of nodal signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038092 ! nodal signaling pathway +relationship: negatively_regulates GO:0038092 ! nodal signaling pathway +created_by: bf +creation_date: 2012-02-16T03:34:23Z + +[Term] +id: GO:1900109 +name: regulation of histone H3-K9 dimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation." [GOC:TermGenie, GOC:vw] +synonym: "regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:0051570 ! regulation of histone H3-K9 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036123 ! histone H3-K9 dimethylation +relationship: regulates GO:0036123 ! histone H3-K9 dimethylation +created_by: bf +creation_date: 2012-02-21T09:06:18Z + +[Term] +id: GO:1900110 +name: negative regulation of histone H3-K9 dimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation." [GOC:TermGenie, GOC:vw] +synonym: "down regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3 K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone H3-K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone lysine H3 K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:0051573 ! negative regulation of histone H3-K9 methylation +is_a: GO:1900109 ! regulation of histone H3-K9 dimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036123 ! histone H3-K9 dimethylation +relationship: negatively_regulates GO:0036123 ! histone H3-K9 dimethylation +created_by: bf +creation_date: 2012-02-21T09:06:22Z + +[Term] +id: GO:1900111 +name: positive regulation of histone H3-K9 dimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation." [GOC:TermGenie, GOC:vw] +synonym: "activation of histone H3 K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "activation of histone H3-K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "activation of histone lysine H3 K9 dimethylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3 K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K9 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone lysine H3 K9 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:0051574 ! positive regulation of histone H3-K9 methylation +is_a: GO:1900109 ! regulation of histone H3-K9 dimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036123 ! histone H3-K9 dimethylation +relationship: positively_regulates GO:0036123 ! histone H3-K9 dimethylation +created_by: bf +creation_date: 2012-02-21T09:06:26Z + +[Term] +id: GO:1900112 +name: regulation of histone H3-K9 trimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation." [GOC:TermGenie] +is_a: GO:0051570 ! regulation of histone H3-K9 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036124 ! histone H3-K9 trimethylation +relationship: regulates GO:0036124 ! histone H3-K9 trimethylation +created_by: bf +creation_date: 2012-02-21T09:09:49Z + +[Term] +id: GO:1900113 +name: negative regulation of histone H3-K9 trimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation." [GOC:TermGenie] +synonym: "down regulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3-K9 trimethylation" NARROW [GOC:TermGenie] +is_a: GO:0051573 ! negative regulation of histone H3-K9 methylation +is_a: GO:1900112 ! regulation of histone H3-K9 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036124 ! histone H3-K9 trimethylation +relationship: negatively_regulates GO:0036124 ! histone H3-K9 trimethylation +created_by: bf +creation_date: 2012-02-21T09:09:54Z + +[Term] +id: GO:1900114 +name: positive regulation of histone H3-K9 trimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation." [GOC:TermGenie] +synonym: "activation of histone H3-K9 trimethylation" NARROW [GOC:TermGenie] +synonym: "up regulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K9 trimethylation" EXACT [GOC:TermGenie] +is_a: GO:0051574 ! positive regulation of histone H3-K9 methylation +is_a: GO:1900112 ! regulation of histone H3-K9 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036124 ! histone H3-K9 trimethylation +relationship: positively_regulates GO:0036124 ! histone H3-K9 trimethylation +created_by: bf +creation_date: 2012-02-21T09:09:58Z + +[Term] +id: GO:1900115 +name: extracellular regulation of signal transduction +namespace: biological_process +def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie] +synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] +synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0009966 ! regulation of signal transduction +intersection_of: occurs_in GO:0005576 ! extracellular region +relationship: occurs_in GO:0005576 ! extracellular region +created_by: bf +creation_date: 2012-02-22T10:21:48Z + +[Term] +id: GO:1900116 +name: extracellular negative regulation of signal transduction +namespace: biological_process +def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie] +synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] +synonym: "extracellular inhibition of signaling pathway" NARROW [GOC:bf] +synonym: "inhibition of signal transduction in extracellular region" NARROW [GOC:TermGenie] +synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] +synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900115 ! extracellular regulation of signal transduction +intersection_of: GO:0009968 ! negative regulation of signal transduction +intersection_of: occurs_in GO:0005576 ! extracellular region +created_by: bf +creation_date: 2012-02-22T10:27:56Z + +[Term] +id: GO:1900117 +name: regulation of execution phase of apoptosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097194 ! execution phase of apoptosis +relationship: regulates GO:0097194 ! execution phase of apoptosis +created_by: pr +creation_date: 2012-02-22T11:26:20Z + +[Term] +id: GO:1900118 +name: negative regulation of execution phase of apoptosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of execution phase of apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:1900117 ! regulation of execution phase of apoptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097194 ! execution phase of apoptosis +relationship: negatively_regulates GO:0097194 ! execution phase of apoptosis +created_by: pr +creation_date: 2012-02-22T11:26:24Z + +[Term] +id: GO:1900119 +name: positive regulation of execution phase of apoptosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "activation of execution phase of apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:1900117 ! regulation of execution phase of apoptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097194 ! execution phase of apoptosis +relationship: positively_regulates GO:0097194 ! execution phase of apoptosis +created_by: pr +creation_date: 2012-02-22T11:26:27Z + +[Term] +id: GO:1900120 +name: regulation of receptor binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie] +synonym: "regulation of receptor ligand" NARROW [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005102 ! signaling receptor binding +relationship: regulates GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2012-02-22T11:40:53Z + +[Term] +id: GO:1900121 +name: negative regulation of receptor binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie] +synonym: "down regulation of receptor binding" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor-associated protein activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor binding" EXACT [GOC:TermGenie] +synonym: "inhibition of receptor binding" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor ligand" NARROW [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005102 ! signaling receptor binding +relationship: negatively_regulates GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2012-02-22T11:40:57Z + +[Term] +id: GO:1900122 +name: positive regulation of receptor binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor." [GOC:signaling, GOC:TermGenie] +synonym: "activation of receptor binding" NARROW [GOC:TermGenie] +synonym: "up regulation of receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor binding" EXACT [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005102 ! signaling receptor binding +relationship: positively_regulates GO:0005102 ! signaling receptor binding +created_by: bf +creation_date: 2012-02-22T11:41:00Z + +[Term] +id: GO:1900123 +name: regulation of nodal receptor complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nodal receptor complex assembly." [GOC:signaling, GOC:TermGenie, PMID:15062104] +synonym: "regulation of ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of nodal receptor complex formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:1900107 ! regulation of nodal signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038099 ! nodal receptor complex assembly +relationship: regulates GO:0038099 ! nodal receptor complex assembly +created_by: bf +creation_date: 2012-02-22T04:21:49Z + +[Term] +id: GO:1900124 +name: negative regulation of nodal receptor complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly." [GOC:signaling, GOC:TermGenie, PMID:15062104] +synonym: "down regulation of ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of nodal receptor complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of nodal receptor complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of nodal receptor complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of nodal receptor complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal receptor complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal receptor complex formation" EXACT [GOC:TermGenie] +synonym: "inhibition of ActRIIB.ALK4.EGF-CFC complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of nodal receptor complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of nodal receptor complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of ActRIIB.ALK4.EGF-CFC complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of nodal receptor complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1900108 ! negative regulation of nodal signaling pathway +is_a: GO:1900123 ! regulation of nodal receptor complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038099 ! nodal receptor complex assembly +relationship: negatively_regulates GO:0038099 ! nodal receptor complex assembly +created_by: bf +creation_date: 2012-02-22T04:21:53Z + +[Term] +id: GO:1900125 +name: regulation of hyaluronan biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030213 ! hyaluronan biosynthetic process +relationship: regulates GO:0030213 ! hyaluronan biosynthetic process +created_by: yaf +creation_date: 2012-02-23T01:09:21Z + +[Term] +id: GO:1900126 +name: negative regulation of hyaluronan biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process +relationship: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process +created_by: yaf +creation_date: 2012-02-23T01:09:29Z + +[Term] +id: GO:1900127 +name: positive regulation of hyaluronan biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] +synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] +synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030213 ! hyaluronan biosynthetic process +relationship: positively_regulates GO:0030213 ! hyaluronan biosynthetic process +created_by: yaf +creation_date: 2012-02-23T01:09:33Z + +[Term] +id: GO:1900128 +name: regulation of G-protein activated inward rectifier potassium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity." [GOC:TermGenie] +synonym: "regulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015467 ! G-protein activated inward rectifier potassium channel activity +relationship: regulates GO:0015467 ! G-protein activated inward rectifier potassium channel activity +created_by: bf +creation_date: 2012-02-23T03:12:53Z + +[Term] +id: GO:1900129 +name: positive regulation of G-protein activated inward rectifier potassium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity." [GOC:TermGenie] +synonym: "activation of G protein activated inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of G protein enhanced inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of G-protein activated inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of G-protein enhanced inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of G-protein-activated inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of G-protein-enhanced inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1900128 ! regulation of G-protein activated inward rectifier potassium channel activity +is_a: GO:1901980 ! positive regulation of inward rectifier potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015467 ! G-protein activated inward rectifier potassium channel activity +relationship: positively_regulates GO:0015467 ! G-protein activated inward rectifier potassium channel activity +created_by: bf +creation_date: 2012-02-23T03:12:58Z + +[Term] +id: GO:1900130 +name: regulation of lipid binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipid binding." [GOC:pm, GOC:TermGenie] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008289 ! lipid binding +relationship: regulates GO:0008289 ! lipid binding +created_by: pm +creation_date: 2012-02-23T04:05:03Z + +[Term] +id: GO:1900131 +name: negative regulation of lipid binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding." [GOC:pm, GOC:TermGenie] +synonym: "down regulation of lipid binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipid binding" EXACT [GOC:TermGenie] +synonym: "downregulation of lipid binding" EXACT [GOC:TermGenie] +synonym: "inhibition of lipid binding" NARROW [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1900130 ! regulation of lipid binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008289 ! lipid binding +relationship: negatively_regulates GO:0008289 ! lipid binding +created_by: pm +creation_date: 2012-02-23T04:05:07Z + +[Term] +id: GO:1900132 +name: positive regulation of lipid binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lipid binding." [GOC:pm, GOC:TermGenie] +synonym: "activation of lipid binding" NARROW [GOC:TermGenie] +synonym: "up regulation of lipid binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipid binding" EXACT [GOC:TermGenie] +synonym: "upregulation of lipid binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1900130 ! regulation of lipid binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008289 ! lipid binding +relationship: positively_regulates GO:0008289 ! lipid binding +created_by: pm +creation_date: 2012-02-23T04:05:11Z + +[Term] +id: GO:1900133 +name: regulation of renin secretion into blood stream +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of renin secretion into blood stream." [GOC:TermGenie] +synonym: "regulation of renin release into blood stream" EXACT [GOC:TermGenie] +is_a: GO:0003073 ! regulation of systemic arterial blood pressure +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0098801 ! regulation of renal system process +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002001 ! renin secretion into blood stream +relationship: regulates GO:0002001 ! renin secretion into blood stream +created_by: rph +creation_date: 2012-02-27T10:32:01Z + +[Term] +id: GO:1900134 +name: negative regulation of renin secretion into blood stream +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream." [GOC:TermGenie] +synonym: "down regulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "down regulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +synonym: "down-regulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "down-regulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +synonym: "downregulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "downregulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +synonym: "inhibition of renin release into blood stream" NARROW [GOC:TermGenie] +synonym: "inhibition of renin secretion into blood stream" NARROW [GOC:TermGenie] +synonym: "negative regulation of renin release into blood stream" EXACT [GOC:TermGenie] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:1900133 ! regulation of renin secretion into blood stream +is_a: GO:1903523 ! negative regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002001 ! renin secretion into blood stream +relationship: negatively_regulates GO:0002001 ! renin secretion into blood stream +created_by: rph +creation_date: 2012-02-27T10:32:05Z + +[Term] +id: GO:1900135 +name: positive regulation of renin secretion into blood stream +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream." [GOC:TermGenie] +synonym: "activation of renin release into blood stream" NARROW [GOC:TermGenie] +synonym: "activation of renin secretion into blood stream" NARROW [GOC:TermGenie] +synonym: "positive regulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "up regulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "up regulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +synonym: "up-regulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "up-regulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +synonym: "upregulation of renin release into blood stream" EXACT [GOC:TermGenie] +synonym: "upregulation of renin secretion into blood stream" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:1900133 ! regulation of renin secretion into blood stream +is_a: GO:1903524 ! positive regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002001 ! renin secretion into blood stream +relationship: positively_regulates GO:0002001 ! renin secretion into blood stream +created_by: rph +creation_date: 2012-02-27T10:32:08Z + +[Term] +id: GO:1900136 +name: regulation of chemokine activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokine activity." [GOC:TermGenie] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:0060300 ! regulation of cytokine activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008009 ! chemokine activity +relationship: regulates GO:0008009 ! chemokine activity +property_value: RO:0002161 NCBITaxon:4751 +created_by: bf +creation_date: 2012-02-28T01:36:29Z + +[Term] +id: GO:1900137 +name: negative regulation of chemokine activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity." [GOC:TermGenie] +synonym: "down regulation of chemokine activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemokine activity" EXACT [GOC:TermGenie] +synonym: "downregulation of chemokine activity" EXACT [GOC:TermGenie] +synonym: "inhibition of chemokine activity" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0060302 ! negative regulation of cytokine activity +is_a: GO:1900136 ! regulation of chemokine activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008009 ! chemokine activity +relationship: negatively_regulates GO:0008009 ! chemokine activity +created_by: bf +creation_date: 2012-02-28T01:36:33Z + +[Term] +id: GO:1900138 +name: negative regulation of phospholipase A2 activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity." [GOC:TermGenie] +synonym: "down regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of lecithinase A activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phospholipase A" RELATED [GOC:TermGenie] +synonym: "down regulation of phospholipase A2 activity" EXACT [GOC:TermGenie] +synonym: "down regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of lecithinase A activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipase A" RELATED [GOC:TermGenie] +synonym: "down-regulation of phospholipase A2 activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of lecithinase A activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of phosphatidolipase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipase A" RELATED [GOC:TermGenie] +synonym: "downregulation of phospholipase A2 activity" EXACT [GOC:TermGenie] +synonym: "downregulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of lecithinase A activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of phosphatidolipase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylcholine 2-acylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phospholipase A" RELATED [GOC:TermGenie] +synonym: "inhibition of phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of lecithinase A activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phospholipase A" RELATED [GOC:TermGenie] +synonym: "negative regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] +is_a: GO:0010519 ! negative regulation of phospholipase activity +is_a: GO:0032429 ! regulation of phospholipase A2 activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004623 ! phospholipase A2 activity +relationship: negatively_regulates GO:0004623 ! phospholipase A2 activity +created_by: rph +creation_date: 2012-03-01T09:18:24Z + +[Term] +id: GO:1900139 +name: negative regulation of arachidonic acid secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion." [GOC:TermGenie] +synonym: "down regulation of arachidonic acid secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of arachidonic acid secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of arachidonic acid secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of arachidonic acid secretion" NARROW [GOC:TermGenie] +is_a: GO:0032304 ! negative regulation of icosanoid secretion +is_a: GO:0090237 ! regulation of arachidonic acid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050482 ! arachidonic acid secretion +relationship: negatively_regulates GO:0050482 ! arachidonic acid secretion +created_by: rph +creation_date: 2012-03-01T09:21:19Z + +[Term] +id: GO:1900140 +name: regulation of seedling development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of seedling development." [GOC:TermGenie] +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090351 ! seedling development +relationship: regulates GO:0090351 ! seedling development +created_by: dhl +creation_date: 2012-03-01T09:26:07Z + +[Term] +id: GO:1900141 +name: regulation of oligodendrocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0034350 ! regulation of glial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097252 ! oligodendrocyte apoptotic process +relationship: regulates GO:0097252 ! oligodendrocyte apoptotic process +created_by: yaf +creation_date: 2012-03-06T10:22:45Z + +[Term] +id: GO:1900142 +name: negative regulation of oligodendrocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0034351 ! negative regulation of glial cell apoptotic process +is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097252 ! oligodendrocyte apoptotic process +relationship: negatively_regulates GO:0097252 ! oligodendrocyte apoptotic process +created_by: yaf +creation_date: 2012-03-06T10:22:50Z + +[Term] +id: GO:1900143 +name: positive regulation of oligodendrocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] +synonym: "activation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0034352 ! positive regulation of glial cell apoptotic process +is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097252 ! oligodendrocyte apoptotic process +relationship: positively_regulates GO:0097252 ! oligodendrocyte apoptotic process +created_by: yaf +creation_date: 2012-03-06T10:22:54Z + +[Term] +id: GO:1900144 +name: positive regulation of BMP secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of BMP secretion." [GOC:sart, GOC:TermGenie] +synonym: "activation of BMP protein secretion" NARROW [GOC:TermGenie] +synonym: "activation of BMP secretion" NARROW [GOC:TermGenie] +synonym: "activation of bone morphogenetic protein secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of BMP protein secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of bone morphogenetic protein secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP protein secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of bone morphogenetic protein secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP protein secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone morphogenetic protein secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP protein secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of bone morphogenetic protein secretion" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:2001284 ! regulation of BMP secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038055 ! BMP secretion +relationship: positively_regulates GO:0038055 ! BMP secretion +created_by: sart +creation_date: 2012-03-06T10:31:47Z + +[Term] +id: GO:1900145 +name: regulation of nodal signaling pathway involved in determination of left/right asymmetry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry." [GOC:BHF, GOC:signaling, GOC:TermGenie, GOC:vk] +synonym: "regulation of nodal signalling pathway involved in determination of left/right asymmetry" EXACT [GOC:mah] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:1900107 ! regulation of nodal signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038107 ! nodal signaling pathway involved in determination of left/right asymmetry +relationship: regulates GO:0038107 ! nodal signaling pathway involved in determination of left/right asymmetry +created_by: bf +creation_date: 2012-03-06T11:00:32Z + +[Term] +id: GO:1900146 +name: negative regulation of nodal signaling pathway involved in determination of left/right asymmetry +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry." [GOC:BHF, GOC:signaling, GOC:TermGenie, GOC:vk] +synonym: "down regulation of nodal signaling pathway involved in determination of left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "down-regulation of nodal signaling pathway involved in determination of left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal signaling pathway involved in determination of left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "inhibition of nodal signaling pathway involved in determination of left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "negative regulation of nodal signalling pathway involved in determination of left/right asymmetry" EXACT [GOC:mah] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1900108 ! negative regulation of nodal signaling pathway +is_a: GO:1900145 ! regulation of nodal signaling pathway involved in determination of left/right asymmetry +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038107 ! nodal signaling pathway involved in determination of left/right asymmetry +relationship: negatively_regulates GO:0038107 ! nodal signaling pathway involved in determination of left/right asymmetry +created_by: bf +creation_date: 2012-03-06T11:00:36Z + +[Term] +id: GO:1900147 +name: regulation of Schwann cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] +is_a: GO:1903975 ! regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036135 ! Schwann cell migration +relationship: regulates GO:0036135 ! Schwann cell migration +created_by: bf +creation_date: 2012-03-06T04:14:50Z + +[Term] +id: GO:1900148 +name: negative regulation of Schwann cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] +synonym: "down regulation of Schwann cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of Schwann cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of Schwann cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of Schwann cell migration" NARROW [GOC:TermGenie] +is_a: GO:1900147 ! regulation of Schwann cell migration +is_a: GO:1903976 ! negative regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036135 ! Schwann cell migration +relationship: negatively_regulates GO:0036135 ! Schwann cell migration +created_by: bf +creation_date: 2012-03-06T04:14:55Z + +[Term] +id: GO:1900149 +name: positive regulation of Schwann cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] +synonym: "activation of Schwann cell migration" NARROW [GOC:TermGenie] +synonym: "up regulation of Schwann cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of Schwann cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of Schwann cell migration" EXACT [GOC:TermGenie] +is_a: GO:1900147 ! regulation of Schwann cell migration +is_a: GO:1903977 ! positive regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036135 ! Schwann cell migration +relationship: positively_regulates GO:0036135 ! Schwann cell migration +created_by: bf +creation_date: 2012-03-06T04:14:58Z + +[Term] +id: GO:1900150 +name: regulation of defense response to fungus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006] +synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie] +synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie] +synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050832 ! defense response to fungus +relationship: regulates GO:0050832 ! defense response to fungus +created_by: dhl +creation_date: 2012-03-06T10:00:16Z + +[Term] +id: GO:1900151 +name: regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay." [GOC:mcc, GOC:TermGenie] +synonym: "regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +is_a: GO:0061013 ! regulation of mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +relationship: regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +created_by: bf +creation_date: 2012-03-07T09:14:43Z + +[Term] +id: GO:1900152 +name: negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay." [GOC:mcc, GOC:TermGenie] +synonym: "down regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down-regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "downregulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "inhibition of deadenylation-dependent mRNA decay" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA breakdown, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolic process, deadenylation-dependent" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolic process, deadenylylation-dependent" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolism, deadenylation-dependent" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolism, deadenylylation-dependent" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA degradation, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "negative regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "negative regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +is_a: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +is_a: GO:1902373 ! negative regulation of mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +relationship: negatively_regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +created_by: bf +creation_date: 2012-03-07T09:14:49Z + +[Term] +id: GO:1900153 +name: positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay." [GOC:mcc, GOC:TermGenie] +synonym: "activation of deadenylation-dependent mRNA decay" NARROW [GOC:TermGenie] +synonym: "activation of mRNA breakdown, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "activation of mRNA catabolic process, deadenylation-dependent" NARROW [GOC:TermGenie] +synonym: "activation of mRNA catabolic process, deadenylylation-dependent" NARROW [GOC:TermGenie] +synonym: "activation of mRNA catabolism, deadenylation-dependent" NARROW [GOC:TermGenie] +synonym: "activation of mRNA catabolism, deadenylylation-dependent" NARROW [GOC:TermGenie] +synonym: "activation of mRNA degradation, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "activation of nuclear mRNA catabolic process, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" NARROW [GOC:TermGenie] +synonym: "positive regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up-regulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "upregulation of deadenylation-dependent mRNA decay" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA breakdown, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA catabolic process, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA catabolic process, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA catabolism, deadenylation-dependent" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA catabolism, deadenylylation-dependent" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA degradation, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" EXACT [GOC:TermGenie] +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +is_a: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +relationship: positively_regulates GO:0000288 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay +created_by: bf +creation_date: 2012-03-07T09:14:52Z + +[Term] +id: GO:1900154 +name: regulation of bone trabecula formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone trabecula formation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060346 ! bone trabecula formation +relationship: regulates GO:0060346 ! bone trabecula formation +created_by: vk +creation_date: 2012-03-07T01:47:03Z + +[Term] +id: GO:1900155 +name: negative regulation of bone trabecula formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "down regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "down regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "down regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "downregulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "downregulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "inhibition of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of bone trabecula formation" NARROW [GOC:TermGenie] +synonym: "inhibition of bone trabeculation" NARROW [GOC:TermGenie] +synonym: "inhibition of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of skeletal trabecula formation" NARROW [GOC:TermGenie] +synonym: "inhibition of skeletal trabeculation" NARROW [GOC:TermGenie] +synonym: "negative regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "negative regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1900154 ! regulation of bone trabecula formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060346 ! bone trabecula formation +relationship: negatively_regulates GO:0060346 ! bone trabecula formation +created_by: vk +creation_date: 2012-03-07T01:47:07Z + +[Term] +id: GO:1900156 +name: positive regulation of bone trabecula formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone trabecula formation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "activation of bone trabecula formation" NARROW [GOC:TermGenie] +synonym: "activation of bone trabeculation" NARROW [GOC:TermGenie] +synonym: "activation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "activation of skeletal trabecula formation" NARROW [GOC:TermGenie] +synonym: "activation of skeletal trabeculation" NARROW [GOC:TermGenie] +synonym: "positive regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "positive regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "up regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "up regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "up regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "up regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal trabeculation" EXACT [GOC:TermGenie] +synonym: "upregulation of bone trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of bone trabecula formation" EXACT [GOC:TermGenie] +synonym: "upregulation of bone trabeculation" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal trabecula biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of skeletal trabecula formation" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal trabeculation" EXACT [GOC:TermGenie] +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1900154 ! regulation of bone trabecula formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060346 ! bone trabecula formation +relationship: positively_regulates GO:0060346 ! bone trabecula formation +created_by: vk +creation_date: 2012-03-07T01:47:10Z + +[Term] +id: GO:1900157 +name: regulation of bone mineralization involved in bone maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation." [GOC:BHF, GOC:TermGenie] +is_a: GO:0030500 ! regulation of bone mineralization +is_a: GO:1903010 ! regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035630 ! bone mineralization involved in bone maturation +relationship: regulates GO:0035630 ! bone mineralization involved in bone maturation +created_by: vk +creation_date: 2012-03-07T08:55:07Z + +[Term] +id: GO:1900158 +name: negative regulation of bone mineralization involved in bone maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of bone mineralization involved in bone maturation" NARROW [GOC:TermGenie] +is_a: GO:0030502 ! negative regulation of bone mineralization +is_a: GO:1900157 ! regulation of bone mineralization involved in bone maturation +is_a: GO:1903011 ! negative regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035630 ! bone mineralization involved in bone maturation +relationship: negatively_regulates GO:0035630 ! bone mineralization involved in bone maturation +created_by: vk +creation_date: 2012-03-07T08:55:12Z + +[Term] +id: GO:1900159 +name: positive regulation of bone mineralization involved in bone maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of bone mineralization involved in bone maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of bone mineralization involved in bone maturation" EXACT [GOC:TermGenie] +is_a: GO:0030501 ! positive regulation of bone mineralization +is_a: GO:1900157 ! regulation of bone mineralization involved in bone maturation +is_a: GO:1903012 ! positive regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035630 ! bone mineralization involved in bone maturation +relationship: positively_regulates GO:0035630 ! bone mineralization involved in bone maturation +created_by: vk +creation_date: 2012-03-07T08:55:16Z + +[Term] +id: GO:1900160 +name: plastid DNA packaging +namespace: biological_process +def: "Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure." [GOC:emb, GOC:TermGenie, PMID:12081370] +synonym: "DNA organisation in plastid" EXACT [GOC:TermGenie] +synonym: "DNA organization in plastid" EXACT [GOC:TermGenie] +synonym: "plastidial DNA packaging" EXACT [GOC:emb] +is_a: GO:0036385 ! nucleoid DNA packaging +intersection_of: GO:0006323 ! DNA packaging +intersection_of: occurs_in GO:0009536 ! plastid +relationship: occurs_in GO:0009536 ! plastid +property_value: RO:0002161 NCBITaxon:2 +property_value: RO:0002161 NCBITaxon:2157 +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 +created_by: bf +creation_date: 2012-03-08T10:51:50Z + +[Term] +id: GO:1900161 +name: regulation of phospholipid scramblase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipid scramblase activity." [GOC:TermGenie] +is_a: GO:0061091 ! regulation of phospholipid translocation +is_a: GO:0110112 ! regulation of lipid transporter activity +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017128 ! phospholipid scramblase activity +relationship: regulates GO:0017128 ! phospholipid scramblase activity +created_by: rph +creation_date: 2012-03-08T10:57:19Z + +[Term] +id: GO:1900162 +name: negative regulation of phospholipid scramblase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity." [GOC:TermGenie] +synonym: "down regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of phospholipid scramblase activity" NARROW [GOC:TermGenie] +is_a: GO:0061093 ! negative regulation of phospholipid translocation +is_a: GO:0110114 ! negative regulation of lipid transporter activity +is_a: GO:1900161 ! regulation of phospholipid scramblase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017128 ! phospholipid scramblase activity +relationship: negatively_regulates GO:0017128 ! phospholipid scramblase activity +created_by: rph +creation_date: 2012-03-08T10:57:23Z + +[Term] +id: GO:1900163 +name: positive regulation of phospholipid scramblase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity." [GOC:TermGenie] +synonym: "activation of phospholipid scramblase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] +is_a: GO:0061092 ! positive regulation of phospholipid translocation +is_a: GO:0110113 ! positive regulation of lipid transporter activity +is_a: GO:1900161 ! regulation of phospholipid scramblase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017128 ! phospholipid scramblase activity +relationship: positively_regulates GO:0017128 ! phospholipid scramblase activity +created_by: rph +creation_date: 2012-03-08T10:57:26Z + +[Term] +id: GO:1900164 +name: nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves." [GOC:BHF, GOC:TermGenie, GOC:vk] +synonym: "nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:mah] +is_a: GO:0038107 ! nodal signaling pathway involved in determination of left/right asymmetry +intersection_of: GO:0038092 ! nodal signaling pathway +intersection_of: part_of GO:0003140 ! determination of left/right asymmetry in lateral mesoderm +relationship: part_of GO:0003140 ! determination of left/right asymmetry in lateral mesoderm +created_by: bf +creation_date: 2012-03-08T02:58:39Z + +[Term] +id: GO:1900165 +name: negative regulation of interleukin-6 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of IL-6 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-6 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-6 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-6 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-6 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-6 secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of IL-6 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-6 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of IL-6 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032715 ! negative regulation of interleukin-6 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072604 ! interleukin-6 secretion +relationship: negatively_regulates GO:0072604 ! interleukin-6 secretion +created_by: yaf +creation_date: 2012-03-08T03:27:05Z + +[Term] +id: GO:1900166 +name: regulation of glial cell-derived neurotrophic factor secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor secretion." [GOC:TermGenie, GOC:yaf] +synonym: "regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "regulation of glial cell line-derived neurotrophic factor secretion" RELATED [] +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +relationship: regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +created_by: yaf +creation_date: 2012-03-08T03:44:39Z + +[Term] +id: GO:1900167 +name: negative regulation of glial cell-derived neurotrophic factor secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor secretion." [GOC:TermGenie, GOC:yaf] +synonym: "down regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of GDNF secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of glial cell line-derived neurotrophic factor secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of glial cell line-derived neurotrophic factor secretion" RELATED [] +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1900166 ! regulation of glial cell-derived neurotrophic factor secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +relationship: negatively_regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +created_by: yaf +creation_date: 2012-03-08T03:44:43Z + +[Term] +id: GO:1900168 +name: positive regulation of glial cell-derived neurotrophic factor secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor secretion." [GOC:TermGenie, GOC:yaf] +synonym: "activation of GDNF secretion" NARROW [GOC:TermGenie] +synonym: "activation of glial cell line-derived neurotrophic factor secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of glial cell line-derived neurotrophic factor secretion" RELATED [] +synonym: "up regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of GDNF secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of glial cell line-derived neurotrophic factor secretion" EXACT [GOC:TermGenie] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1900166 ! regulation of glial cell-derived neurotrophic factor secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +relationship: positively_regulates GO:0044467 ! glial cell-derived neurotrophic factor secretion +created_by: yaf +creation_date: 2012-03-08T03:44:47Z + +[Term] +id: GO:1900169 +name: regulation of glucocorticoid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway." [GOC:TermGenie] +synonym: "regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043402 ! glucocorticoid mediated signaling pathway +relationship: regulates GO:0043402 ! glucocorticoid mediated signaling pathway +created_by: hjd +creation_date: 2012-03-08T08:33:16Z + +[Term] +id: GO:1900170 +name: negative regulation of glucocorticoid mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway." [GOC:TermGenie] +synonym: "down regulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "downregulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "inhibition of glucocorticoid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of glucocorticoid mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900169 ! regulation of glucocorticoid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043402 ! glucocorticoid mediated signaling pathway +relationship: negatively_regulates GO:0043402 ! glucocorticoid mediated signaling pathway +created_by: hjd +creation_date: 2012-03-08T08:33:20Z + +[Term] +id: GO:1900171 +name: positive regulation of glucocorticoid mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway." [GOC:TermGenie] +synonym: "activation of glucocorticoid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of glucocorticoid mediated signalling" NARROW [GOC:TermGenie] +synonym: "positive regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "up regulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +synonym: "upregulation of glucocorticoid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of glucocorticoid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900169 ! regulation of glucocorticoid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043402 ! glucocorticoid mediated signaling pathway +relationship: positively_regulates GO:0043402 ! glucocorticoid mediated signaling pathway +created_by: hjd +creation_date: 2012-03-08T08:33:23Z + +[Term] +id: GO:1900175 +name: regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm." [GOC:BHF, GOC:TermGenie, GOC:vk] +synonym: "regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:mah] +is_a: GO:1900145 ! regulation of nodal signaling pathway involved in determination of left/right asymmetry +is_a: GO:2000380 ! regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: bf +creation_date: 2012-03-09T10:39:10Z + +[Term] +id: GO:1900176 +name: negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm." [GOC:BHF, GOC:TermGenie, GOC:vk, PMID:15084459] +synonym: "down-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "downregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "inhibition of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "negative regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:mah] +is_a: GO:1900146 ! negative regulation of nodal signaling pathway involved in determination of left/right asymmetry +is_a: GO:1900175 ! regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +is_a: GO:2000381 ! negative regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: negatively_regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: bf +creation_date: 2012-03-09T10:39:14Z + +[Term] +id: GO:1900177 +name: regulation of aflatoxin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process." [GOC:di] +synonym: "regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045122 ! aflatoxin biosynthetic process +relationship: regulates GO:0045122 ! aflatoxin biosynthetic process +created_by: di +creation_date: 2012-03-09T11:23:35Z + +[Term] +id: GO:1900178 +name: negative regulation of aflatoxin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process." [GOC:di] +synonym: "down regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of aflatoxin anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aflatoxin biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of aflatoxin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aflatoxin formation" NARROW [GOC:TermGenie] +synonym: "inhibition of aflatoxin synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900177 ! regulation of aflatoxin biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045122 ! aflatoxin biosynthetic process +relationship: negatively_regulates GO:0045122 ! aflatoxin biosynthetic process +created_by: di +creation_date: 2012-03-09T11:23:42Z + +[Term] +id: GO:1900179 +name: positive regulation of aflatoxin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process." [GOC:di] +synonym: "activation of aflatoxin anabolism" NARROW [GOC:TermGenie] +synonym: "activation of aflatoxin biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of aflatoxin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of aflatoxin formation" NARROW [GOC:TermGenie] +synonym: "activation of aflatoxin synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of aflatoxin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aflatoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of aflatoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aflatoxin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of aflatoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900177 ! regulation of aflatoxin biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045122 ! aflatoxin biosynthetic process +relationship: positively_regulates GO:0045122 ! aflatoxin biosynthetic process +created_by: di +creation_date: 2012-03-09T11:23:46Z + +[Term] +id: GO:1900180 +name: regulation of protein localization to nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] +synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034504 ! protein localization to nucleus +relationship: regulates GO:0034504 ! protein localization to nucleus +created_by: bf +creation_date: 2012-03-12T01:23:44Z + +[Term] +id: GO:1900181 +name: negative regulation of protein localization to nucleus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] +synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to nucleus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in cell nucleus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in nucleus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to nucleus" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +is_a: GO:1900180 ! regulation of protein localization to nucleus +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034504 ! protein localization to nucleus +relationship: negatively_regulates GO:0034504 ! protein localization to nucleus +created_by: bf +creation_date: 2012-03-12T01:23:48Z + +[Term] +id: GO:1900182 +name: positive regulation of protein localization to nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] +synonym: "activation of protein localisation to nucleus" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in cell nucleus" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "activation of protein localization to nucleus" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie] +is_a: GO:1900180 ! regulation of protein localization to nucleus +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034504 ! protein localization to nucleus +relationship: positively_regulates GO:0034504 ! protein localization to nucleus +created_by: bf +creation_date: 2012-03-12T01:23:52Z + +[Term] +id: GO:1900183 +name: regulation of xanthone-containing compound biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001307 ! xanthone-containing compound biosynthetic process +relationship: regulates GO:2001307 ! xanthone-containing compound biosynthetic process +created_by: di +creation_date: 2012-03-16T03:30:14Z + +[Term] +id: GO:1900184 +name: negative regulation of xanthone-containing compound biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "down regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "downregulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of xanthone-containing compound biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "inhibition of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of xanthones anabolism" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900183 ! regulation of xanthone-containing compound biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001307 ! xanthone-containing compound biosynthetic process +relationship: negatively_regulates GO:2001307 ! xanthone-containing compound biosynthetic process +created_by: di +creation_date: 2012-03-16T03:30:24Z + +[Term] +id: GO:1900185 +name: positive regulation of xanthone-containing compound biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "activation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of xanthone-containing compound biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "activation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "up regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of xanthone biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of xanthone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of xanthone-containing compound anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of xanthone-containing compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of xanthone-containing compound biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of xanthone-containing compound formation" EXACT [GOC:TermGenie] +synonym: "upregulation of xanthone-containing compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900183 ! regulation of xanthone-containing compound biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001307 ! xanthone-containing compound biosynthetic process +relationship: positively_regulates GO:2001307 ! xanthone-containing compound biosynthetic process +created_by: di +creation_date: 2012-03-16T03:30:32Z + +[Term] +id: GO:1900186 +name: negative regulation of clathrin-dependent endocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis." [GOC:TermGenie] +synonym: "down regulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of clathrin-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of clathrin-mediated endocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin-mediated endocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin-mediated endocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of clathrin coated pit-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of clathrin-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of clathrin-mediated endocytosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of clathrin-dependent endocytosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of clathrin-mediated endocytosis" EXACT [] +is_a: GO:0048261 ! negative regulation of receptor-mediated endocytosis +is_a: GO:2000369 ! regulation of clathrin-dependent endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072583 ! clathrin-dependent endocytosis +relationship: negatively_regulates GO:0072583 ! clathrin-dependent endocytosis +created_by: hjd +creation_date: 2012-03-16T05:25:02Z + +[Term] +id: GO:1900187 +name: regulation of cell adhesion involved in single-species biofilm formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation." [GOC:di, GOC:TermGenie] +synonym: "regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +is_a: GO:0010810 ! regulation of cell-substrate adhesion +is_a: GO:1900190 ! regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +relationship: regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:38:45Z + +[Term] +id: GO:1900188 +name: negative regulation of cell adhesion involved in single-species biofilm formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation." [GOC:di, GOC:TermGenie] +synonym: "down regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "down regulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "downregulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "downregulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "inhibition of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "inhibition of cell adhesion involved in single-species biofilm formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +is_a: GO:0010812 ! negative regulation of cell-substrate adhesion +is_a: GO:1900187 ! regulation of cell adhesion involved in single-species biofilm formation +is_a: GO:1900191 ! negative regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +relationship: negatively_regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:38:54Z + +[Term] +id: GO:1900189 +name: positive regulation of cell adhesion involved in single-species biofilm formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation." [GOC:di, GOC:TermGenie] +synonym: "activation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "activation of cell adhesion involved in single-species biofilm formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "up regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "up regulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "upregulation of cell adhesion during single-species biofilm formation" RELATED [GOC:TermGenie] +synonym: "upregulation of cell adhesion involved in single-species biofilm formation" EXACT [GOC:TermGenie] +is_a: GO:0010811 ! positive regulation of cell-substrate adhesion +is_a: GO:1900187 ! regulation of cell adhesion involved in single-species biofilm formation +is_a: GO:1900192 ! positive regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +relationship: positively_regulates GO:0043709 ! cell adhesion involved in single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:39:03Z + +[Term] +id: GO:1900190 +name: regulation of single-species biofilm formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single-species biofilm formation." [GOC:di, GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044010 ! single-species biofilm formation +relationship: regulates GO:0044010 ! single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:42:04Z + +[Term] +id: GO:1900191 +name: negative regulation of single-species biofilm formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation." [GOC:di, GOC:TermGenie] +synonym: "down regulation of single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "downregulation of single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "inhibition of single-species biofilm formation" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1900190 ! regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044010 ! single-species biofilm formation +relationship: negatively_regulates GO:0044010 ! single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:42:13Z + +[Term] +id: GO:1900192 +name: positive regulation of single-species biofilm formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of single-species biofilm formation." [GOC:di, GOC:TermGenie] +synonym: "activation of single-species biofilm formation" NARROW [GOC:TermGenie] +synonym: "up regulation of single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of single-species biofilm formation" EXACT [GOC:TermGenie] +synonym: "upregulation of single-species biofilm formation" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1900190 ! regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044010 ! single-species biofilm formation +relationship: positively_regulates GO:0044010 ! single-species biofilm formation +created_by: di +creation_date: 2012-03-19T12:42:21Z + +[Term] +id: GO:1900193 +name: regulation of oocyte maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] +is_a: GO:0060281 ! regulation of oocyte development +is_a: GO:1903429 ! regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001556 ! oocyte maturation +relationship: regulates GO:0001556 ! oocyte maturation +created_by: kmv +creation_date: 2012-03-19T09:41:18Z + +[Term] +id: GO:1900194 +name: negative regulation of oocyte maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] +synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of oocyte maturation" NARROW [GOC:TermGenie] +is_a: GO:0060283 ! negative regulation of oocyte development +is_a: GO:1900193 ! regulation of oocyte maturation +is_a: GO:1903430 ! negative regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001556 ! oocyte maturation +relationship: negatively_regulates GO:0001556 ! oocyte maturation +created_by: kmv +creation_date: 2012-03-19T09:41:27Z + +[Term] +id: GO:1900195 +name: positive regulation of oocyte maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] +synonym: "activation of oocyte maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie] +is_a: GO:0060282 ! positive regulation of oocyte development +is_a: GO:1900193 ! regulation of oocyte maturation +is_a: GO:1903431 ! positive regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001556 ! oocyte maturation +relationship: positively_regulates GO:0001556 ! oocyte maturation +created_by: kmv +creation_date: 2012-03-19T09:41:35Z + +[Term] +id: GO:1900196 +name: regulation of penicillin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of penicillin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "regulation of penicillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0033244 ! regulation of penicillin metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042318 ! penicillin biosynthetic process +relationship: regulates GO:0042318 ! penicillin biosynthetic process +created_by: di +creation_date: 2012-03-20T03:56:33Z + +[Term] +id: GO:1900197 +name: negative regulation of penicillin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of penicillin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of penicillin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of penicillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0033245 ! negative regulation of penicillin metabolic process +is_a: GO:1900196 ! regulation of penicillin biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042318 ! penicillin biosynthetic process +relationship: negatively_regulates GO:0042318 ! penicillin biosynthetic process +created_by: di +creation_date: 2012-03-20T03:56:43Z + +[Term] +id: GO:1900198 +name: positive regulation of penicillin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of penicillin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "activation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of penicillin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of penicillin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of penicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of penicillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of penicillin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of penicillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0033246 ! positive regulation of penicillin metabolic process +is_a: GO:1900196 ! regulation of penicillin biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042318 ! penicillin biosynthetic process +relationship: positively_regulates GO:0042318 ! penicillin biosynthetic process +created_by: di +creation_date: 2012-03-20T03:56:52Z + +[Term] +id: GO:1900199 +name: positive regulation of protein export from nucleus during meiotic anaphase II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II." [GOC:al, GOC:TermGenie, PMID:20970342] +synonym: "positive regulation of protein export from nucleus involved in meiotic anaphase II" BROAD [GOC:pr] +is_a: GO:0046827 ! positive regulation of protein export from nucleus +intersection_of: GO:0065007 ! biological regulation +intersection_of: happens_during GO:0007138 ! meiotic anaphase II +intersection_of: positively_regulates GO:0006611 ! protein export from nucleus +relationship: happens_during GO:0007138 ! meiotic anaphase II +created_by: pr +creation_date: 2012-03-20T06:35:19Z + +[Term] +id: GO:1900200 +name: mesenchymal cell apoptotic process involved in metanephros development +namespace: biological_process +def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "mesenchymal cell apoptosis involved in metanephros development" NARROW [] +is_a: GO:0097152 ! mesenchymal cell apoptotic process +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0097152 ! mesenchymal cell apoptotic process +intersection_of: part_of GO:0001656 ! metanephros development +relationship: part_of GO:0001656 ! metanephros development +created_by: yaf +creation_date: 2012-03-21T11:58:05Z + +[Term] +id: GO:1900201 +name: obsolete regulation of spread of virus in host, cell to cell +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of spread of virus in host, cell to cell." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "regulation of spread of virus in host, cell to cell" EXACT [] +synonym: "regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pm +creation_date: 2012-03-21T01:15:41Z + +[Term] +id: GO:1900202 +name: obsolete negative regulation of spread of virus in host, cell to cell +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of spread of virus in host, cell to cell." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "down regulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "down regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "down regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "down-regulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "downregulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "downregulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "downregulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "downregulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "inhibition of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "inhibition of spread of virus in host, cell to cell" NARROW [GOC:TermGenie] +synonym: "inhibition of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "inhibition of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "negative regulation of spread of virus in host, cell to cell" EXACT [] +synonym: "negative regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pm +creation_date: 2012-03-21T01:15:51Z + +[Term] +id: GO:1900203 +name: obsolete positive regulation of spread of virus in host, cell to cell +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of spread of virus in host, cell to cell." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "activation of spread of virus in host, cell to cell" NARROW [GOC:TermGenie] +synonym: "activation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "activation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "positive regulation of spread of virus in host, cell to cell" EXACT [] +synonym: "positive regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "up regulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "up-regulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "upregulation of cell to cell spread of virus within host" EXACT [GOC:TermGenie] +synonym: "upregulation of spread of virus in host, cell to cell" EXACT [GOC:TermGenie] +synonym: "upregulation of spread of virus within host, cell to cell" EXACT [GOC:TermGenie] +synonym: "upregulation of viral spread within host, cell to cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pm +creation_date: 2012-03-21T01:16:00Z + +[Term] +id: GO:1900204 +name: apoptotic process involved in metanephric collecting duct development +namespace: biological_process +def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0072205 ! metanephric collecting duct development +relationship: part_of GO:0072205 ! metanephric collecting duct development +created_by: yaf +creation_date: 2012-03-21T01:21:32Z + +[Term] +id: GO:1900205 +name: apoptotic process involved in metanephric nephron tubule development +namespace: biological_process +def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +is_a: GO:1902742 ! apoptotic process involved in development +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0072234 ! metanephric nephron tubule development +relationship: part_of GO:0072234 ! metanephric nephron tubule development +created_by: yaf +creation_date: 2012-03-21T01:21:45Z + +[Term] +id: GO:1900206 +name: regulation of pronephric nephron tubule development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie] +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039020 ! pronephric nephron tubule development +relationship: regulates GO:0039020 ! pronephric nephron tubule development +created_by: bf +creation_date: 2012-03-22T09:23:13Z + +[Term] +id: GO:1900207 +name: negative regulation of pronephric nephron tubule development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706] +synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "inhibition of pronephric nephron tubule development" NARROW [GOC:TermGenie] +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:1900206 ! regulation of pronephric nephron tubule development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039020 ! pronephric nephron tubule development +relationship: negatively_regulates GO:0039020 ! pronephric nephron tubule development +created_by: bf +creation_date: 2012-03-22T09:23:23Z + +[Term] +id: GO:1900208 +name: regulation of cardiolipin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiolipin metabolic process." [GOC:TermGenie] +synonym: "regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032048 ! cardiolipin metabolic process +relationship: regulates GO:0032048 ! cardiolipin metabolic process +created_by: jl +creation_date: 2012-03-22T10:43:33Z + +[Term] +id: GO:1900209 +name: negative regulation of cardiolipin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process." [GOC:TermGenie] +synonym: "down regulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "downregulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of cardiolipin metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "inhibition of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +is_a: GO:1900208 ! regulation of cardiolipin metabolic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032048 ! cardiolipin metabolic process +relationship: negatively_regulates GO:0032048 ! cardiolipin metabolic process +created_by: jl +creation_date: 2012-03-22T10:43:43Z + +[Term] +id: GO:1900210 +name: positive regulation of cardiolipin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process." [GOC:TermGenie] +synonym: "activation of cardiolipin metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "activation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "activation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of cardiolipin metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiolipin metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of diphosphatidylglycerol metabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of diphosphatidylglycerol metabolism" RELATED [GOC:TermGenie] +is_a: GO:1900208 ! regulation of cardiolipin metabolic process +is_a: GO:1903727 ! positive regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032048 ! cardiolipin metabolic process +relationship: positively_regulates GO:0032048 ! cardiolipin metabolic process +created_by: jl +creation_date: 2012-03-22T10:43:51Z + +[Term] +id: GO:1900211 +name: regulation of mesenchymal cell apoptotic process involved in metanephros development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:1904748 ! regulation of apoptotic process involved in development +is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +relationship: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +created_by: yaf +creation_date: 2012-03-22T10:52:50Z + +[Term] +id: GO:1900212 +name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +synonym: "inhibition of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] +synonym: "negative regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +relationship: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +created_by: yaf +creation_date: 2012-03-22T10:53:00Z + +[Term] +id: GO:1900213 +name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "activation of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] +synonym: "positive regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] +synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +relationship: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +created_by: yaf +creation_date: 2012-03-22T10:53:09Z + +[Term] +id: GO:1900214 +name: regulation of apoptotic process involved in metanephric collecting duct development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +relationship: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +created_by: yaf +creation_date: 2012-03-22T10:53:21Z + +[Term] +id: GO:1900215 +name: negative regulation of apoptotic process involved in metanephric collecting duct development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "down regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "down regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "down-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "downregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "inhibition of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "negative regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +relationship: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +created_by: yaf +creation_date: 2012-03-22T10:53:31Z + +[Term] +id: GO:1900216 +name: positive regulation of apoptotic process involved in metanephric collecting duct development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "activation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "activation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "activation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "positive regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "up regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "up-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] +synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] +synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +relationship: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development +created_by: yaf +creation_date: 2012-03-22T10:53:39Z + +[Term] +id: GO:1900217 +name: regulation of apoptotic process involved in metanephric nephron tubule development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +relationship: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +created_by: yaf +creation_date: 2012-03-22T10:53:51Z + +[Term] +id: GO:1900218 +name: negative regulation of apoptotic process involved in metanephric nephron tubule development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "down regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "down regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "down-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "downregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "inhibition of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "negative regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +relationship: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +created_by: yaf +creation_date: 2012-03-22T10:54:01Z + +[Term] +id: GO:1900219 +name: positive regulation of apoptotic process involved in metanephric nephron tubule development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] +synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "activation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "activation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "activation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "positive regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "up regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "up-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] +synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] +synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +relationship: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development +created_by: yaf +creation_date: 2012-03-22T10:54:09Z + +[Term] +id: GO:1900220 +name: semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis +namespace: biological_process +def: "Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis." [GOC:BHF, GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway of bone trabecula morphogenesis" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway of bone trabecula morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:0061430 ! bone trabecula morphogenesis +relationship: part_of GO:0061430 ! bone trabecula morphogenesis +created_by: vk +creation_date: 2012-03-22T01:13:56Z + +[Term] +id: GO:1900221 +name: regulation of amyloid-beta clearance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amyloid-beta clearance." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of beta-amyloid clearance" EXACT [] +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097242 ! amyloid-beta clearance +relationship: regulates GO:0097242 ! amyloid-beta clearance +created_by: vk +creation_date: 2012-03-22T01:29:32Z + +[Term] +id: GO:1900222 +name: negative regulation of amyloid-beta clearance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +synonym: "inhibition of beta-amyloid clearance" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-amyloid clearance" EXACT [] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1900221 ! regulation of amyloid-beta clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097242 ! amyloid-beta clearance +relationship: negatively_regulates GO:0097242 ! amyloid-beta clearance +created_by: vk +creation_date: 2012-03-22T01:29:41Z + +[Term] +id: GO:1900223 +name: positive regulation of amyloid-beta clearance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance." [GOC:BHF, GOC:TermGenie] +synonym: "activation of beta-amyloid clearance" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-amyloid clearance" EXACT [] +synonym: "up regulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-amyloid clearance" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1900221 ! regulation of amyloid-beta clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097242 ! amyloid-beta clearance +relationship: positively_regulates GO:0097242 ! amyloid-beta clearance +created_by: vk +creation_date: 2012-03-22T01:29:50Z + +[Term] +id: GO:1900224 +name: positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry." [GOC:BHF, GOC:TermGenie] +synonym: "activation of nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "activation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "activation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "positive regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "positive regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "positive regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:mah] +synonym: "up regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "up regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "up-regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "up-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up-regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "upregulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +synonym: "upregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "upregulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm" EXACT [GOC:TermGenie] +is_a: GO:0032927 ! positive regulation of activin receptor signaling pathway +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1900175 ! regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +is_a: GO:2000382 ! positive regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: positively_regulates GO:1900164 ! nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: vk +creation_date: 2012-03-22T02:30:13Z + +[Term] +id: GO:1900225 +name: regulation of NLRP3 inflammasome complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly." [GOC:TermGenie] +synonym: "regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044546 ! NLRP3 inflammasome complex assembly +relationship: regulates GO:0044546 ! NLRP3 inflammasome complex assembly +created_by: jl +creation_date: 2012-03-22T04:18:14Z + +[Term] +id: GO:1900226 +name: negative regulation of NLRP3 inflammasome complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly." [GOC:TermGenie] +synonym: "down regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "down regulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "down-regulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "downregulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "inhibition of NLRP3 inflammasome complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1900225 ! regulation of NLRP3 inflammasome complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044546 ! NLRP3 inflammasome complex assembly +relationship: negatively_regulates GO:0044546 ! NLRP3 inflammasome complex assembly +created_by: jl +creation_date: 2012-03-22T04:18:24Z + +[Term] +id: GO:1900227 +name: positive regulation of NLRP3 inflammasome complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly." [GOC:TermGenie] +synonym: "activation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "activation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "activation of NLRP3 inflammasome complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "up regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "up regulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "up-regulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of NALP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of NLRP3 inflammasome activation" RELATED [GOC:TermGenie] +synonym: "upregulation of NLRP3 inflammasome complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1900225 ! regulation of NLRP3 inflammasome complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044546 ! NLRP3 inflammasome complex assembly +relationship: positively_regulates GO:0044546 ! NLRP3 inflammasome complex assembly +created_by: jl +creation_date: 2012-03-22T04:18:32Z + +[Term] +id: GO:1900228 +name: regulation of single-species biofilm formation in or on host organism +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism." [GOC:di, GOC:TermGenie] +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +is_a: GO:1900190 ! regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044407 ! single-species biofilm formation in or on host organism +relationship: regulates GO:0044407 ! single-species biofilm formation in or on host organism +created_by: di +creation_date: 2012-03-23T04:36:54Z + +[Term] +id: GO:1900229 +name: negative regulation of single-species biofilm formation in or on host organism +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism." [GOC:di, GOC:TermGenie] +synonym: "down regulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +synonym: "down-regulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +synonym: "downregulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +synonym: "inhibition of single-species biofilm formation in or on host organism" NARROW [GOC:TermGenie] +is_a: GO:1900191 ! negative regulation of single-species biofilm formation +is_a: GO:1900228 ! regulation of single-species biofilm formation in or on host organism +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044407 ! single-species biofilm formation in or on host organism +relationship: negatively_regulates GO:0044407 ! single-species biofilm formation in or on host organism +created_by: di +creation_date: 2012-03-23T04:37:05Z + +[Term] +id: GO:1900230 +name: positive regulation of single-species biofilm formation in or on host organism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism." [GOC:di, GOC:TermGenie] +synonym: "activation of single-species biofilm formation in or on host organism" NARROW [GOC:TermGenie] +synonym: "up regulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +synonym: "up-regulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +synonym: "upregulation of single-species biofilm formation in or on host organism" EXACT [GOC:TermGenie] +is_a: GO:1900192 ! positive regulation of single-species biofilm formation +is_a: GO:1900228 ! regulation of single-species biofilm formation in or on host organism +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044407 ! single-species biofilm formation in or on host organism +relationship: positively_regulates GO:0044407 ! single-species biofilm formation in or on host organism +created_by: di +creation_date: 2012-03-23T04:37:14Z + +[Term] +id: GO:1900231 +name: regulation of single-species biofilm formation on inanimate substrate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate." [GOC:di, GOC:TermGenie] +is_a: GO:1900190 ! regulation of single-species biofilm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +relationship: regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +created_by: di +creation_date: 2012-03-23T04:40:35Z + +[Term] +id: GO:1900232 +name: negative regulation of single-species biofilm formation on inanimate substrate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate." [GOC:di, GOC:TermGenie] +synonym: "down regulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +synonym: "down-regulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +synonym: "downregulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +synonym: "inhibition of single-species biofilm formation on inanimate substrate" NARROW [GOC:TermGenie] +is_a: GO:1900191 ! negative regulation of single-species biofilm formation +is_a: GO:1900231 ! regulation of single-species biofilm formation on inanimate substrate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +relationship: negatively_regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +created_by: di +creation_date: 2012-03-23T04:40:45Z + +[Term] +id: GO:1900233 +name: positive regulation of single-species biofilm formation on inanimate substrate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate." [GOC:di, GOC:TermGenie] +synonym: "activation of single-species biofilm formation on inanimate substrate" NARROW [GOC:TermGenie] +synonym: "up regulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +synonym: "up-regulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +synonym: "upregulation of single-species biofilm formation on inanimate substrate" EXACT [GOC:TermGenie] +is_a: GO:1900192 ! positive regulation of single-species biofilm formation +is_a: GO:1900231 ! regulation of single-species biofilm formation on inanimate substrate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +relationship: positively_regulates GO:0044011 ! single-species biofilm formation on inanimate substrate +created_by: di +creation_date: 2012-03-23T04:40:53Z + +[Term] +id: GO:1900234 +name: regulation of Kit signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Kit signaling pathway." [GOC:signaling, GOC:TermGenie] +synonym: "regulation of Kit signalling pathway" EXACT [GOC:mah] +synonym: "regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038109 ! Kit signaling pathway +relationship: regulates GO:0038109 ! Kit signaling pathway +created_by: bf +creation_date: 2012-03-23T02:54:13Z + +[Term] +id: GO:1900235 +name: negative regulation of Kit signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway." [GOC:signaling, GOC:TermGenie] +synonym: "down regulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of Kit signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of Kit signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1900234 ! regulation of Kit signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038109 ! Kit signaling pathway +relationship: negatively_regulates GO:0038109 ! Kit signaling pathway +created_by: bf +creation_date: 2012-03-23T02:54:23Z + +[Term] +id: GO:1900236 +name: positive regulation of Kit signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Kit signaling pathway." [GOC:signaling, GOC:TermGenie] +synonym: "activation of Kit signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "activation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of Kit signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Kit signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of stem cell factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of stem cell factor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1900234 ! regulation of Kit signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038109 ! Kit signaling pathway +relationship: positively_regulates GO:0038109 ! Kit signaling pathway +created_by: bf +creation_date: 2012-03-23T02:54:32Z + +[Term] +id: GO:1900237 +name: positive regulation of induction of conjugation with cellular fusion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion." [GOC:TermGenie] +synonym: "up regulation of induction of conjugation with cellular fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of induction of conjugation with cellular fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of induction of conjugation with cellular fusion" EXACT [GOC:TermGenie] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010514 ! induction of conjugation with cellular fusion +relationship: positively_regulates GO:0010514 ! induction of conjugation with cellular fusion +created_by: al +creation_date: 2012-03-26T10:14:16Z + +[Term] +id: GO:1900238 +name: regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway." [GOC:mtg_kidney_jan10, GOC:TermGenie, goc:yaf, PMID:19450854] +synonym: "regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +synonym: "regulation of metanephric mesenchyme chemotaxis by platelet-derived growth factor receptor-beta signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +is_a: GO:2000589 ! regulation of metanephric mesenchymal cell migration +intersection_of: GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +intersection_of: regulates GO:0035789 ! metanephric mesenchymal cell migration +created_by: yaf +creation_date: 2012-03-27T03:33:56Z + +[Term] +id: GO:1900239 +name: regulation of phenotypic switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phenotypic switching." [GOC:di, GOC:TermGenie] +synonym: "regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036166 ! phenotypic switching +relationship: regulates GO:0036166 ! phenotypic switching +created_by: di +creation_date: 2012-03-28T01:49:16Z + +[Term] +id: GO:1900240 +name: negative regulation of phenotypic switching +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching." [GOC:di, GOC:TermGenie] +synonym: "down regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down regulation of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down-regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down-regulation of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "downregulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "downregulation of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "inhibition of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "inhibition of phenotypic switching" NARROW [GOC:TermGenie] +synonym: "negative regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1900239 ! regulation of phenotypic switching +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036166 ! phenotypic switching +relationship: negatively_regulates GO:0036166 ! phenotypic switching +created_by: di +creation_date: 2012-03-28T01:49:26Z + +[Term] +id: GO:1900241 +name: positive regulation of phenotypic switching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phenotypic switching." [GOC:di, GOC:TermGenie] +synonym: "activation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "activation of phenotypic switching" NARROW [GOC:TermGenie] +synonym: "positive regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up regulation of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up-regulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up-regulation of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "upregulation of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "upregulation of phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1900239 ! regulation of phenotypic switching +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036166 ! phenotypic switching +relationship: positively_regulates GO:0036166 ! phenotypic switching +created_by: di +creation_date: 2012-03-28T01:49:34Z + +[Term] +id: GO:1900242 +name: regulation of synaptic vesicle endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis." [GOC:BHF, GOC:TermGenie] +subset: goslim_synapse +synonym: "regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:1903421 ! regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048488 ! synaptic vesicle endocytosis +relationship: regulates GO:0048488 ! synaptic vesicle endocytosis +created_by: rl +creation_date: 2012-03-28T01:40:26Z + +[Term] +id: GO:1900243 +name: negative regulation of synaptic vesicle endocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle endocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:1900242 ! regulation of synaptic vesicle endocytosis +is_a: GO:1903422 ! negative regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048488 ! synaptic vesicle endocytosis +relationship: negatively_regulates GO:0048488 ! synaptic vesicle endocytosis +created_by: rl +creation_date: 2012-03-28T01:40:36Z + +[Term] +id: GO:1900244 +name: positive regulation of synaptic vesicle endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis." [GOC:BHF, GOC:TermGenie] +synonym: "activation of synaptic vesicle endocytosis" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle endocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle retrieval" RELATED [GOC:TermGenie] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:1900242 ! regulation of synaptic vesicle endocytosis +is_a: GO:1903423 ! positive regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048488 ! synaptic vesicle endocytosis +relationship: positively_regulates GO:0048488 ! synaptic vesicle endocytosis +created_by: rl +creation_date: 2012-03-28T01:40:44Z + +[Term] +id: GO:1900245 +name: positive regulation of MDA-5 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway." [GOC:TermGenie] +synonym: "activation of IFIH1 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of MDA-5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of MDA5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of melanoma differentiation-associated gene 5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of IFIH1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of MDA-5 signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of MDA5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of IFIH1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of MDA-5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of MDA5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of IFIH1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of MDA-5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of MDA5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of IFIH1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of MDA-5 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of MDA5 signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of melanoma differentiation-associated gene 5 signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0039533 ! regulation of MDA-5 signaling pathway +is_a: GO:0062208 ! positive regulation of pattern recognition receptor signaling pathway +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0039530 ! MDA-5 signaling pathway +relationship: positively_regulates GO:0039530 ! MDA-5 signaling pathway +created_by: ss +creation_date: 2012-04-02T10:55:38Z + +[Term] +id: GO:1900246 +name: positive regulation of RIG-I signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway." [GOC:TermGenie] +synonym: "activation of DDX58 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of retinoic acid inducible gene I signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of RIG-I signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of DDX58 signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of retinoic acid inducible gene I signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of RIG-I signalling pathway" EXACT [GOC:mah] +synonym: "up regulation of DDX58 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of retinoic acid inducible gene I signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of RIG-I signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of DDX58 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinoic acid inducible gene I signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of RIG-I signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of DDX58 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of retinoic acid inducible gene I signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of RIG-I signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0039535 ! regulation of RIG-I signaling pathway +is_a: GO:0062208 ! positive regulation of pattern recognition receptor signaling pathway +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0039529 ! RIG-I signaling pathway +relationship: positively_regulates GO:0039529 ! RIG-I signaling pathway +created_by: ss +creation_date: 2012-04-02T11:00:28Z + +[Term] +id: GO:1900247 +name: regulation of cytoplasmic translational elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] +is_a: GO:0006448 ! regulation of translational elongation +is_a: GO:2000765 ! regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002182 ! cytoplasmic translational elongation +relationship: regulates GO:0002182 ! cytoplasmic translational elongation +created_by: vw +creation_date: 2012-04-03T05:07:02Z + +[Term] +id: GO:1900248 +name: negative regulation of cytoplasmic translational elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] +synonym: "down regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of cytoplasmic translational elongation" NARROW [GOC:TermGenie] +is_a: GO:0045900 ! negative regulation of translational elongation +is_a: GO:1900247 ! regulation of cytoplasmic translational elongation +is_a: GO:2000766 ! negative regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002182 ! cytoplasmic translational elongation +relationship: negatively_regulates GO:0002182 ! cytoplasmic translational elongation +created_by: vw +creation_date: 2012-04-03T05:07:14Z + +[Term] +id: GO:1900249 +name: positive regulation of cytoplasmic translational elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation." [GOC:TermGenie] +synonym: "activation of cytoplasmic translational elongation" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of cytoplasmic translational elongation" EXACT [GOC:TermGenie] +is_a: GO:0045901 ! positive regulation of translational elongation +is_a: GO:1900247 ! regulation of cytoplasmic translational elongation +is_a: GO:2000767 ! positive regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002182 ! cytoplasmic translational elongation +relationship: positively_regulates GO:0002182 ! cytoplasmic translational elongation +created_by: vw +creation_date: 2012-04-03T05:07:24Z + +[Term] +id: GO:1900256 +name: regulation of beta1-adrenergic receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity." [GOC:TermGenie] +synonym: "regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004940 ! beta1-adrenergic receptor activity +relationship: regulates GO:0004940 ! beta1-adrenergic receptor activity +created_by: tb +creation_date: 2012-04-03T10:59:21Z + +[Term] +id: GO:1900257 +name: negative regulation of beta1-adrenergic receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity." [GOC:TermGenie] +synonym: "down regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "down regulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "downregulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +synonym: "inhibition of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "inhibition of beta1-adrenergic receptor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:1900256 ! regulation of beta1-adrenergic receptor activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004940 ! beta1-adrenergic receptor activity +relationship: negatively_regulates GO:0004940 ! beta1-adrenergic receptor activity +created_by: tb +creation_date: 2012-04-03T10:59:40Z + +[Term] +id: GO:1900258 +name: positive regulation of beta1-adrenergic receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity." [GOC:TermGenie] +synonym: "activation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "activation of beta1-adrenergic receptor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "up regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "up regulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta1 adrenoceptor" EXACT [GOC:TermGenie] +synonym: "upregulation of beta1-adrenergic receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0071879 ! positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway +is_a: GO:1900256 ! regulation of beta1-adrenergic receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004940 ! beta1-adrenergic receptor activity +relationship: positively_regulates GO:0004940 ! beta1-adrenergic receptor activity +created_by: tb +creation_date: 2012-04-03T10:59:49Z + +[Term] +id: GO:1900259 +name: regulation of RNA-directed 5'-3' RNA polymerase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity." [GOC:pf, GOC:TermGenie] +synonym: "regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA-directed RNA polymerase activity" BROAD [] +synonym: "regulation of transcriptase" BROAD [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +is_a: GO:1903506 ! regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +relationship: regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:01:53Z + +[Term] +id: GO:1900260 +name: negative regulation of RNA-directed 5'-3' RNA polymerase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity." [GOC:pf, GOC:TermGenie] +synonym: "down regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "down regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "down regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "down regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "down regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "down regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "down regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "down-regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "down-regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "down-regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "down-regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "down-regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "down-regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "down-regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "downregulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "downregulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "downregulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "downregulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "downregulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "downregulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RDRP" RELATED [GOC:TermGenie] +synonym: "downregulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "inhibition of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "inhibition of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "inhibition of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "inhibition of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "inhibition of polymerase L" RELATED [GOC:TermGenie] +synonym: "inhibition of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RDRP" RELATED [GOC:TermGenie] +synonym: "inhibition of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA-directed RNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of transcriptase" BROAD [GOC:TermGenie] +synonym: "negative regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "negative regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "negative regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "negative regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "negative regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "negative regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "negative regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA-directed RNA polymerase activity" BROAD [] +synonym: "negative regulation of transcriptase" BROAD [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1900259 ! regulation of RNA-directed 5'-3' RNA polymerase activity +is_a: GO:1903507 ! negative regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +relationship: negatively_regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:02:03Z + +[Term] +id: GO:1900261 +name: positive regulation of RNA-directed 5'-3' RNA polymerase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity." [GOC:pf, GOC:TermGenie] +synonym: "activation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "activation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "activation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "activation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "activation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "activation of polymerase L" RELATED [GOC:TermGenie] +synonym: "activation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of RDRP" RELATED [GOC:TermGenie] +synonym: "activation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "activation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "activation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "activation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "activation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "activation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "activation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "activation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of RNA-directed RNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of transcriptase" BROAD [GOC:TermGenie] +synonym: "positive regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "positive regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "positive regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "positive regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "positive regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "positive regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "positive regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA-directed RNA polymerase activity" BROAD [] +synonym: "positive regulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "up regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "up regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "up regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "up regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "up regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "up regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "up regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "up-regulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "up-regulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "up-regulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "up-regulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "up-regulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "up-regulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RDRP" RELATED [GOC:TermGenie] +synonym: "up-regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcriptase" BROAD [GOC:TermGenie] +synonym: "upregulation of 3D polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] +synonym: "upregulation of PB1 proteins" RELATED [GOC:TermGenie] +synonym: "upregulation of PB2 proteins" RELATED [GOC:TermGenie] +synonym: "upregulation of phage f2 replicase" NARROW [GOC:TermGenie] +synonym: "upregulation of polymerase L" RELATED [GOC:TermGenie] +synonym: "upregulation of Q-beta replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RDRP" RELATED [GOC:TermGenie] +synonym: "upregulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA synthetase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of transcriptase" BROAD [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1900259 ! regulation of RNA-directed 5'-3' RNA polymerase activity +is_a: GO:1903508 ! positive regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +relationship: positively_regulates GO:0003968 ! RNA-directed 5'-3' RNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:02:11Z + +[Term] +id: GO:1900262 +name: regulation of DNA-directed DNA polymerase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity." [GOC:TermGenie] +synonym: "regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003887 ! DNA-directed DNA polymerase activity +relationship: regulates GO:0003887 ! DNA-directed DNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:07:08Z + +[Term] +id: GO:1900263 +name: negative regulation of DNA-directed DNA polymerase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity." [GOC:TermGenie] +synonym: "down regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "down regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "down regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "down regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "down regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "down regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "down regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "down-regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "down-regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "down-regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "down-regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "down-regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "down-regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of duplicase" BROAD [GOC:TermGenie] +synonym: "downregulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "downregulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of sequenase" RELATED [GOC:TermGenie] +synonym: "downregulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "downregulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "downregulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "downregulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "inhibition of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of duplicase" BROAD [GOC:TermGenie] +synonym: "inhibition of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "inhibition of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sequenase" RELATED [GOC:TermGenie] +synonym: "inhibition of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "inhibition of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "inhibition of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "inhibition of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "negative regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "negative regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "negative regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "negative regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "negative regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "negative regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1900262 ! regulation of DNA-directed DNA polymerase activity +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003887 ! DNA-directed DNA polymerase activity +relationship: negatively_regulates GO:0003887 ! DNA-directed DNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:07:18Z + +[Term] +id: GO:1900264 +name: positive regulation of DNA-directed DNA polymerase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity." [GOC:TermGenie] +synonym: "activation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "activation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "activation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "activation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "activation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "activation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "activation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "activation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "activation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "activation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "activation of DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of duplicase" BROAD [GOC:TermGenie] +synonym: "activation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "activation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of sequenase" RELATED [GOC:TermGenie] +synonym: "activation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "activation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "activation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "activation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "positive regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "positive regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "positive regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "positive regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "positive regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "positive regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "up regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "up regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "up regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "up regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "up regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "up regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of duplicase" BROAD [GOC:TermGenie] +synonym: "up-regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "up-regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of sequenase" RELATED [GOC:TermGenie] +synonym: "up-regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "up-regulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "up-regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "up-regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA duplicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA polymerase alpha" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase beta" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase gamma" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase I" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase II" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase III" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA polymerase V activity" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA replicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of duplicase" BROAD [GOC:TermGenie] +synonym: "upregulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of Klenow fragment" NARROW [GOC:TermGenie] +synonym: "upregulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of sequenase" RELATED [GOC:TermGenie] +synonym: "upregulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of Taq DNA polymerase" NARROW [GOC:TermGenie] +synonym: "upregulation of Taq Pol I" NARROW [GOC:TermGenie] +synonym: "upregulation of Tca DNA polymerase" NARROW [GOC:TermGenie] +synonym: "upregulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1900262 ! regulation of DNA-directed DNA polymerase activity +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003887 ! DNA-directed DNA polymerase activity +relationship: positively_regulates GO:0003887 ! DNA-directed DNA polymerase activity +created_by: tb +creation_date: 2012-04-03T11:07:27Z + +[Term] +id: GO:1900265 +name: regulation of substance P receptor binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of substance P receptor binding." [GOC:TermGenie] +synonym: "regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031835 ! substance P receptor binding +relationship: regulates GO:0031835 ! substance P receptor binding +created_by: tb +creation_date: 2012-04-03T11:11:27Z + +[Term] +id: GO:1900266 +name: negative regulation of substance P receptor binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding." [GOC:TermGenie] +synonym: "down regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "down regulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "down regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "down-regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "downregulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "inhibition of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "inhibition of substance P receptor binding" NARROW [GOC:TermGenie] +synonym: "inhibition of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "negative regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +is_a: GO:1900121 ! negative regulation of receptor binding +is_a: GO:1900265 ! regulation of substance P receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031835 ! substance P receptor binding +relationship: negatively_regulates GO:0031835 ! substance P receptor binding +created_by: tb +creation_date: 2012-04-03T11:11:36Z + +[Term] +id: GO:1900267 +name: positive regulation of substance P receptor binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of substance P receptor binding." [GOC:TermGenie] +synonym: "activation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "activation of substance P receptor binding" NARROW [GOC:TermGenie] +synonym: "activation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "positive regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "up regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "up regulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "up regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "up-regulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of substance P receptor ligand" NARROW [GOC:TermGenie] +synonym: "upregulation of neurokinin-1 receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of substance P receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of substance P receptor ligand" NARROW [GOC:TermGenie] +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:1900265 ! regulation of substance P receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031835 ! substance P receptor binding +relationship: positively_regulates GO:0031835 ! substance P receptor binding +created_by: tb +creation_date: 2012-04-03T11:11:45Z + +[Term] +id: GO:1900268 +name: regulation of reverse transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reverse transcription." [GOC:TermGenie] +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001171 ! reverse transcription +relationship: regulates GO:0001171 ! reverse transcription +created_by: tb +creation_date: 2012-04-03T11:13:26Z + +[Term] +id: GO:1900269 +name: negative regulation of reverse transcription +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription." [GOC:TermGenie] +synonym: "down regulation of reverse transcription" EXACT [GOC:TermGenie] +synonym: "down-regulation of reverse transcription" EXACT [GOC:TermGenie] +synonym: "downregulation of reverse transcription" EXACT [GOC:TermGenie] +synonym: "inhibition of reverse transcription" NARROW [GOC:TermGenie] +is_a: GO:1900268 ! regulation of reverse transcription +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001171 ! reverse transcription +relationship: negatively_regulates GO:0001171 ! reverse transcription +created_by: tb +creation_date: 2012-04-03T11:13:35Z + +[Term] +id: GO:1900270 +name: positive regulation of reverse transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of reverse transcription." [GOC:TermGenie] +synonym: "activation of reverse transcription" NARROW [GOC:TermGenie] +synonym: "up regulation of reverse transcription" EXACT [GOC:TermGenie] +synonym: "up-regulation of reverse transcription" EXACT [GOC:TermGenie] +synonym: "upregulation of reverse transcription" EXACT [GOC:TermGenie] +is_a: GO:1900268 ! regulation of reverse transcription +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001171 ! reverse transcription +relationship: positively_regulates GO:0001171 ! reverse transcription +created_by: tb +creation_date: 2012-04-03T11:13:43Z + +[Term] +id: GO:1900271 +name: regulation of long-term synaptic potentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of long-term synaptic potentiation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "regulation of LTP" RELATED [GOC:TermGenie] +is_a: GO:0048167 ! regulation of synaptic plasticity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060291 ! long-term synaptic potentiation +relationship: regulates GO:0060291 ! long-term synaptic potentiation +created_by: rl +creation_date: 2012-04-04T07:17:13Z + +[Term] +id: GO:1900272 +name: negative regulation of long-term synaptic potentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "down regulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of LTP" RELATED [GOC:TermGenie] +synonym: "down-regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "down-regulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of LTP" RELATED [GOC:TermGenie] +synonym: "downregulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "downregulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of LTP" RELATED [GOC:TermGenie] +synonym: "inhibition of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "inhibition of long-term synaptic potentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of LTP" RELATED [GOC:TermGenie] +synonym: "negative regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "negative regulation of LTP" RELATED [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1900271 ! regulation of long-term synaptic potentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060291 ! long-term synaptic potentiation +relationship: negatively_regulates GO:0060291 ! long-term synaptic potentiation +created_by: rl +creation_date: 2012-04-04T07:17:21Z + +[Term] +id: GO:1900273 +name: positive regulation of long-term synaptic potentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "activation of long-term synaptic potentiation" NARROW [GOC:TermGenie] +synonym: "activation of LTP" RELATED [GOC:TermGenie] +synonym: "positive regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "positive regulation of LTP" RELATED [GOC:TermGenie] +synonym: "up regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "up regulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of LTP" RELATED [GOC:TermGenie] +synonym: "up-regulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "up-regulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of LTP" RELATED [GOC:TermGenie] +synonym: "upregulation of long-term potentiation" BROAD [GOC:TermGenie] +synonym: "upregulation of long-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of LTP" RELATED [GOC:TermGenie] +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:1900271 ! regulation of long-term synaptic potentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060291 ! long-term synaptic potentiation +relationship: positively_regulates GO:0060291 ! long-term synaptic potentiation +created_by: rl +creation_date: 2012-04-04T07:17:30Z + +[Term] +id: GO:1900274 +name: regulation of phospholipase C activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipase C activity." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "regulation of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "regulation of phosphatidase C" RELATED [GOC:TermGenie] +is_a: GO:0010517 ! regulation of phospholipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004629 ! phospholipase C activity +relationship: regulates GO:0004629 ! phospholipase C activity +created_by: rl +creation_date: 2012-04-04T01:19:00Z + +[Term] +id: GO:1900275 +name: negative regulation of phospholipase C activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "down regulation of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "down regulation of phosphatidase C" RELATED [GOC:TermGenie] +synonym: "down regulation of phospholipase C activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "down-regulation of phosphatidase C" RELATED [GOC:TermGenie] +synonym: "down-regulation of phospholipase C activity" EXACT [GOC:TermGenie] +synonym: "downregulation of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "downregulation of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "downregulation of phosphatidase C" RELATED [GOC:TermGenie] +synonym: "downregulation of phospholipase C activity" EXACT [GOC:TermGenie] +synonym: "inhibition of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "inhibition of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "inhibition of phosphatidase C" RELATED [GOC:TermGenie] +synonym: "inhibition of phospholipase C activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of lecithinase C activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of lipophosphodiesterase C" RELATED [GOC:TermGenie] +synonym: "negative regulation of phosphatidase C" RELATED [GOC:TermGenie] +is_a: GO:0010519 ! negative regulation of phospholipase activity +is_a: GO:1900274 ! regulation of phospholipase C activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004629 ! phospholipase C activity +relationship: negatively_regulates GO:0004629 ! phospholipase C activity +created_by: rl +creation_date: 2012-04-04T01:19:10Z + +[Term] +id: GO:1900276 +name: regulation of proteinase activated receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proteinase activated receptor activity." [GOC:BHF, GOC:TermGenie] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001648 ! proteinase activated receptor activity +relationship: regulates GO:0001648 ! proteinase activated receptor activity +created_by: rl +creation_date: 2012-04-04T01:31:20Z + +[Term] +id: GO:1900277 +name: negative regulation of proteinase activated receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +synonym: "inhibition of proteinase activated receptor activity" NARROW [GOC:TermGenie] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:1900276 ! regulation of proteinase activated receptor activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001648 ! proteinase activated receptor activity +relationship: negatively_regulates GO:0001648 ! proteinase activated receptor activity +created_by: rl +creation_date: 2012-04-04T01:31:29Z + +[Term] +id: GO:1900278 +name: positive regulation of proteinase activated receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity." [GOC:BHF, GOC:TermGenie] +synonym: "activation of proteinase activated receptor activity" NARROW [GOC:TermGenie] +synonym: "up regulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of proteinase activated receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:1900276 ! regulation of proteinase activated receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001648 ! proteinase activated receptor activity +relationship: positively_regulates GO:0001648 ! proteinase activated receptor activity +created_by: rl +creation_date: 2012-04-04T01:31:37Z + +[Term] +id: GO:1900279 +name: regulation of CD4-positive, alpha-beta T cell costimulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation." [GOC:BHF, GOC:pr, GOC:TermGenie] +synonym: "regulation of CD4-positive, alpha beta T cell costimulation" EXACT [] +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000523 ! regulation of T cell costimulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +relationship: regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +created_by: rl +creation_date: 2012-04-04T08:56:15Z + +[Term] +id: GO:1900280 +name: negative regulation of CD4-positive, alpha-beta T cell costimulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation." [GOC:BHF, GOC:pr, GOC:TermGenie] +synonym: "down regulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +synonym: "downregulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +synonym: "inhibition of CD4-positive, alpha beta T cell costimulation" NARROW [GOC:TermGenie] +synonym: "negative regulation of CD4-positive, alpha beta T cell costimulation" EXACT [] +is_a: GO:1900279 ! regulation of CD4-positive, alpha-beta T cell costimulation +is_a: GO:2000524 ! negative regulation of T cell costimulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +relationship: negatively_regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +created_by: rl +creation_date: 2012-04-04T08:56:26Z + +[Term] +id: GO:1900281 +name: positive regulation of CD4-positive, alpha-beta T cell costimulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation." [GOC:BHF, GOC:pr, GOC:TermGenie] +synonym: "activation of CD4-positive, alpha beta T cell costimulation" NARROW [GOC:TermGenie] +synonym: "positive regulation of CD4-positive, alpha beta T cell costimulation" EXACT [] +synonym: "up regulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +synonym: "upregulation of CD4-positive, alpha beta T cell costimulation" EXACT [GOC:TermGenie] +is_a: GO:1900279 ! regulation of CD4-positive, alpha-beta T cell costimulation +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000525 ! positive regulation of T cell costimulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +relationship: positively_regulates GO:0035783 ! CD4-positive, alpha-beta T cell costimulation +created_by: rl +creation_date: 2012-04-04T08:56:45Z + +[Term] +id: GO:1900282 +name: regulation of cellobiose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellobiose catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:2000930 ! regulation of cellobiose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000892 ! cellobiose catabolic process +relationship: regulates GO:2000892 ! cellobiose catabolic process +created_by: tt +creation_date: 2012-04-05T12:28:50Z + +[Term] +id: GO:1900283 +name: negative regulation of cellobiose catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of cellobiose catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of cellobiose catabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:1900282 ! regulation of cellobiose catabolic process +is_a: GO:2000931 ! negative regulation of cellobiose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000892 ! cellobiose catabolic process +relationship: negatively_regulates GO:2000892 ! cellobiose catabolic process +created_by: tt +creation_date: 2012-04-05T12:29:00Z + +[Term] +id: GO:1900284 +name: positive regulation of cellobiose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of cellobiose catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of cellobiose catabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellobiose catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of cellobiose catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cellobiose catabolism" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:1900282 ! regulation of cellobiose catabolic process +is_a: GO:2000932 ! positive regulation of cellobiose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000892 ! cellobiose catabolic process +relationship: positively_regulates GO:2000892 ! cellobiose catabolic process +created_by: tt +creation_date: 2012-04-05T12:29:09Z + +[Term] +id: GO:1900285 +name: regulation of cellotriose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellotriose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001096 ! cellotriose transport +relationship: regulates GO:2001096 ! cellotriose transport +created_by: tt +creation_date: 2012-04-05T05:56:46Z + +[Term] +id: GO:1900286 +name: negative regulation of cellotriose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of cellotriose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellotriose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of cellotriose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of cellotriose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900285 ! regulation of cellotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001096 ! cellotriose transport +relationship: negatively_regulates GO:2001096 ! cellotriose transport +created_by: tt +creation_date: 2012-04-05T05:56:56Z + +[Term] +id: GO:1900287 +name: positive regulation of cellotriose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of cellotriose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of cellotriose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellotriose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of cellotriose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900285 ! regulation of cellotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001096 ! cellotriose transport +relationship: positively_regulates GO:2001096 ! cellotriose transport +created_by: tt +creation_date: 2012-04-05T05:57:05Z + +[Term] +id: GO:1900288 +name: regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +relationship: regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +created_by: tt +creation_date: 2012-04-05T06:02:41Z + +[Term] +id: GO:1900289 +name: negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme F420-dependent nitroimidazole breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme F420-dependent nitroimidazole catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme F420-dependent nitroimidazole reduction" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900288 ! regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +relationship: negatively_regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +created_by: tt +creation_date: 2012-04-05T06:02:51Z + +[Term] +id: GO:1900290 +name: positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme F420-dependent nitroimidazole breakdown" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme F420-dependent nitroimidazole catabolism" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme F420-dependent nitroimidazole reduction" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "positive regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme F420-dependent nitroimidazole breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme F420-dependent nitroimidazole catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme F420-dependent nitroimidazole reduction" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme F420-dependent nitroreductase activity" RELATED [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900288 ! regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +relationship: positively_regulates GO:0052799 ! coenzyme F420-dependent bicyclic nitroimidazole catabolic process +created_by: tt +creation_date: 2012-04-05T06:02:59Z + +[Term] +id: GO:1900291 +name: regulation of galactotriose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of galactotriose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001093 ! galactotriose transport +relationship: regulates GO:2001093 ! galactotriose transport +created_by: tt +creation_date: 2012-04-05T07:25:58Z + +[Term] +id: GO:1900292 +name: negative regulation of galactotriose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of galactotriose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of galactotriose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of galactotriose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of galactotriose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900291 ! regulation of galactotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001093 ! galactotriose transport +relationship: negatively_regulates GO:2001093 ! galactotriose transport +created_by: tt +creation_date: 2012-04-05T07:26:08Z + +[Term] +id: GO:1900293 +name: positive regulation of galactotriose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of galactotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of galactotriose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of galactotriose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of galactotriose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of galactotriose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900291 ! regulation of galactotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001093 ! galactotriose transport +relationship: positively_regulates GO:2001093 ! galactotriose transport +created_by: tt +creation_date: 2012-04-05T07:26:28Z + +[Term] +id: GO:1900294 +name: regulation of heptasaccharide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heptasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001104 ! heptasaccharide transport +relationship: regulates GO:2001104 ! heptasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:40:40Z + +[Term] +id: GO:1900295 +name: negative regulation of heptasaccharide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of heptasaccharide transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of heptasaccharide transport" EXACT [GOC:TermGenie] +synonym: "downregulation of heptasaccharide transport" EXACT [GOC:TermGenie] +synonym: "inhibition of heptasaccharide transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900294 ! regulation of heptasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001104 ! heptasaccharide transport +relationship: negatively_regulates GO:2001104 ! heptasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:40:49Z + +[Term] +id: GO:1900296 +name: positive regulation of heptasaccharide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heptasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of heptasaccharide transport" NARROW [GOC:TermGenie] +synonym: "up regulation of heptasaccharide transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of heptasaccharide transport" EXACT [GOC:TermGenie] +synonym: "upregulation of heptasaccharide transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900294 ! regulation of heptasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001104 ! heptasaccharide transport +relationship: positively_regulates GO:2001104 ! heptasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:40:58Z + +[Term] +id: GO:1900297 +name: regulation of hexasaccharide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hexasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001102 ! hexasaccharide transport +relationship: regulates GO:2001102 ! hexasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:44:31Z + +[Term] +id: GO:1900298 +name: negative regulation of hexasaccharide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of hexasaccharide transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexasaccharide transport" EXACT [GOC:TermGenie] +synonym: "downregulation of hexasaccharide transport" EXACT [GOC:TermGenie] +synonym: "inhibition of hexasaccharide transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900297 ! regulation of hexasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001102 ! hexasaccharide transport +relationship: negatively_regulates GO:2001102 ! hexasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:44:40Z + +[Term] +id: GO:1900299 +name: positive regulation of hexasaccharide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hexasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of hexasaccharide transport" NARROW [GOC:TermGenie] +synonym: "up regulation of hexasaccharide transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexasaccharide transport" EXACT [GOC:TermGenie] +synonym: "upregulation of hexasaccharide transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900297 ! regulation of hexasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001102 ! hexasaccharide transport +relationship: positively_regulates GO:2001102 ! hexasaccharide transport +created_by: tt +creation_date: 2012-04-05T07:44:49Z + +[Term] +id: GO:1900300 +name: regulation of laminarabiose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of laminarabiose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001086 ! laminarabiose transport +relationship: regulates GO:2001086 ! laminarabiose transport +created_by: tt +creation_date: 2012-04-05T07:57:19Z + +[Term] +id: GO:1900301 +name: negative regulation of laminarabiose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of laminarabiose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of laminarabiose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of laminarabiose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of laminarabiose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900300 ! regulation of laminarabiose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001086 ! laminarabiose transport +relationship: negatively_regulates GO:2001086 ! laminarabiose transport +created_by: tt +creation_date: 2012-04-05T07:57:28Z + +[Term] +id: GO:1900302 +name: positive regulation of laminarabiose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of laminarabiose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of laminarabiose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of laminarabiose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of laminarabiose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of laminarabiose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900300 ! regulation of laminarabiose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001086 ! laminarabiose transport +relationship: positively_regulates GO:2001086 ! laminarabiose transport +created_by: tt +creation_date: 2012-04-05T07:57:37Z + +[Term] +id: GO:1900303 +name: regulation of laminaritriose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of laminaritriose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001097 ! laminaritriose transport +relationship: regulates GO:2001097 ! laminaritriose transport +created_by: tt +creation_date: 2012-04-05T07:57:49Z + +[Term] +id: GO:1900304 +name: negative regulation of laminaritriose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of laminaritriose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of laminaritriose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of laminaritriose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of laminaritriose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900303 ! regulation of laminaritriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001097 ! laminaritriose transport +relationship: negatively_regulates GO:2001097 ! laminaritriose transport +created_by: tt +creation_date: 2012-04-05T07:57:58Z + +[Term] +id: GO:1900305 +name: positive regulation of laminaritriose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of laminaritriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of laminaritriose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of laminaritriose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of laminaritriose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of laminaritriose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900303 ! regulation of laminaritriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001097 ! laminaritriose transport +relationship: positively_regulates GO:2001097 ! laminaritriose transport +created_by: tt +creation_date: 2012-04-05T07:58:06Z + +[Term] +id: GO:1900306 +name: regulation of maltoheptaose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltoheptaose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1900294 ! regulation of heptasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001105 ! maltoheptaose transport +relationship: regulates GO:2001105 ! maltoheptaose transport +created_by: tt +creation_date: 2012-04-05T07:58:18Z + +[Term] +id: GO:1900307 +name: negative regulation of maltoheptaose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltoheptaose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltoheptaose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltoheptaose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltoheptaose transport" NARROW [GOC:TermGenie] +is_a: GO:1900295 ! negative regulation of heptasaccharide transport +is_a: GO:1900306 ! regulation of maltoheptaose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001105 ! maltoheptaose transport +relationship: negatively_regulates GO:2001105 ! maltoheptaose transport +created_by: tt +creation_date: 2012-04-05T07:58:27Z + +[Term] +id: GO:1900308 +name: positive regulation of maltoheptaose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltoheptaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltoheptaose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltoheptaose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltoheptaose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltoheptaose transport" EXACT [GOC:TermGenie] +is_a: GO:1900296 ! positive regulation of heptasaccharide transport +is_a: GO:1900306 ! regulation of maltoheptaose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001105 ! maltoheptaose transport +relationship: positively_regulates GO:2001105 ! maltoheptaose transport +created_by: tt +creation_date: 2012-04-05T07:58:35Z + +[Term] +id: GO:1900309 +name: regulation of maltoheptaose metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001122 ! maltoheptaose metabolic process +relationship: regulates GO:2001122 ! maltoheptaose metabolic process +created_by: tt +creation_date: 2012-04-05T07:58:48Z + +[Term] +id: GO:1900310 +name: negative regulation of maltoheptaose metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of maltoheptaose metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of maltoheptaose metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:1900309 ! regulation of maltoheptaose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001122 ! maltoheptaose metabolic process +relationship: negatively_regulates GO:2001122 ! maltoheptaose metabolic process +created_by: tt +creation_date: 2012-04-05T07:58:58Z + +[Term] +id: GO:1900311 +name: positive regulation of maltoheptaose metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltoheptaose metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of maltoheptaose metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of maltoheptaose metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of maltoheptaose metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:1900309 ! regulation of maltoheptaose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001122 ! maltoheptaose metabolic process +relationship: positively_regulates GO:2001122 ! maltoheptaose metabolic process +created_by: tt +creation_date: 2012-04-05T07:59:06Z + +[Term] +id: GO:1900312 +name: regulation of maltohexaose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltohexaose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1900297 ! regulation of hexasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001103 ! maltohexaose transport +relationship: regulates GO:2001103 ! maltohexaose transport +created_by: tt +creation_date: 2012-04-05T07:59:18Z + +[Term] +id: GO:1900313 +name: negative regulation of maltohexaose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltohexaose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltohexaose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltohexaose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltohexaose transport" NARROW [GOC:TermGenie] +is_a: GO:1900298 ! negative regulation of hexasaccharide transport +is_a: GO:1900312 ! regulation of maltohexaose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001103 ! maltohexaose transport +relationship: negatively_regulates GO:2001103 ! maltohexaose transport +created_by: tt +creation_date: 2012-04-05T07:59:26Z + +[Term] +id: GO:1900314 +name: positive regulation of maltohexaose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltohexaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltohexaose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltohexaose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltohexaose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltohexaose transport" EXACT [GOC:TermGenie] +is_a: GO:1900299 ! positive regulation of hexasaccharide transport +is_a: GO:1900312 ! regulation of maltohexaose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001103 ! maltohexaose transport +relationship: positively_regulates GO:2001103 ! maltohexaose transport +created_by: tt +creation_date: 2012-04-05T07:59:35Z + +[Term] +id: GO:1900315 +name: regulation of maltopentaose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltopentaose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1900360 ! regulation of pentasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001101 ! maltopentaose transport +relationship: regulates GO:2001101 ! maltopentaose transport +created_by: tt +creation_date: 2012-04-05T07:59:47Z + +[Term] +id: GO:1900316 +name: negative regulation of maltopentaose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltopentaose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltopentaose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltopentaose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltopentaose transport" NARROW [GOC:TermGenie] +is_a: GO:1900315 ! regulation of maltopentaose transport +is_a: GO:1900361 ! negative regulation of pentasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001101 ! maltopentaose transport +relationship: negatively_regulates GO:2001101 ! maltopentaose transport +created_by: tt +creation_date: 2012-04-05T07:59:56Z + +[Term] +id: GO:1900317 +name: positive regulation of maltopentaose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltopentaose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltopentaose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltopentaose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltopentaose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltopentaose transport" EXACT [GOC:TermGenie] +is_a: GO:1900315 ! regulation of maltopentaose transport +is_a: GO:1900362 ! positive regulation of pentasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001101 ! maltopentaose transport +relationship: positively_regulates GO:2001101 ! maltopentaose transport +created_by: tt +creation_date: 2012-04-05T08:00:04Z + +[Term] +id: GO:1900318 +name: regulation of methane biosynthetic process from dimethylamine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001129 ! methane biosynthetic process from dimethylamine +relationship: regulates GO:2001129 ! methane biosynthetic process from dimethylamine +created_by: tt +creation_date: 2012-04-06T01:43:21Z + +[Term] +id: GO:1900319 +name: negative regulation of methane biosynthetic process from dimethylamine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from dimethylamine" NARROW [GOC:TermGenie] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900318 ! regulation of methane biosynthetic process from dimethylamine +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001129 ! methane biosynthetic process from dimethylamine +relationship: negatively_regulates GO:2001129 ! methane biosynthetic process from dimethylamine +created_by: tt +creation_date: 2012-04-06T01:43:31Z + +[Term] +id: GO:1900320 +name: positive regulation of methane biosynthetic process from dimethylamine +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from dimethylamine" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from dimethylamine" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900318 ! regulation of methane biosynthetic process from dimethylamine +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001129 ! methane biosynthetic process from dimethylamine +relationship: positively_regulates GO:2001129 ! methane biosynthetic process from dimethylamine +created_by: tt +creation_date: 2012-04-06T01:43:40Z + +[Term] +id: GO:1900321 +name: regulation of maltotetraose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltotetraose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001099 ! maltotetraose transport +relationship: regulates GO:2001099 ! maltotetraose transport +created_by: tt +creation_date: 2012-04-06T01:45:36Z + +[Term] +id: GO:1900322 +name: negative regulation of maltotetraose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltotetraose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltotetraose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltotetraose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltotetraose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900321 ! regulation of maltotetraose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001099 ! maltotetraose transport +relationship: negatively_regulates GO:2001099 ! maltotetraose transport +created_by: tt +creation_date: 2012-04-06T01:45:45Z + +[Term] +id: GO:1900323 +name: positive regulation of maltotetraose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltotetraose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltotetraose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltotetraose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltotetraose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltotetraose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900321 ! regulation of maltotetraose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001099 ! maltotetraose transport +relationship: positively_regulates GO:2001099 ! maltotetraose transport +created_by: tt +creation_date: 2012-04-06T01:45:54Z + +[Term] +id: GO:1900324 +name: regulation of maltotriulose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltotriulose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001090 ! maltotriulose transport +relationship: regulates GO:2001090 ! maltotriulose transport +created_by: tt +creation_date: 2012-04-06T01:48:06Z + +[Term] +id: GO:1900325 +name: negative regulation of maltotriulose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of maltotriulose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltotriulose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltotriulose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltotriulose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900324 ! regulation of maltotriulose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001090 ! maltotriulose transport +relationship: negatively_regulates GO:2001090 ! maltotriulose transport +created_by: tt +creation_date: 2012-04-06T01:48:16Z + +[Term] +id: GO:1900326 +name: positive regulation of maltotriulose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltotriulose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of maltotriulose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltotriulose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltotriulose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltotriulose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900324 ! regulation of maltotriulose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001090 ! maltotriulose transport +relationship: positively_regulates GO:2001090 ! maltotriulose transport +created_by: tt +creation_date: 2012-04-06T01:48:25Z + +[Term] +id: GO:1900327 +name: regulation of mannotriose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mannotriose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001095 ! mannotriose transport +relationship: regulates GO:2001095 ! mannotriose transport +created_by: tt +creation_date: 2012-04-06T01:50:05Z + +[Term] +id: GO:1900328 +name: negative regulation of mannotriose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of mannotriose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of mannotriose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of mannotriose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of mannotriose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900327 ! regulation of mannotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001095 ! mannotriose transport +relationship: negatively_regulates GO:2001095 ! mannotriose transport +created_by: tt +creation_date: 2012-04-06T01:50:13Z + +[Term] +id: GO:1900329 +name: positive regulation of mannotriose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mannotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of mannotriose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of mannotriose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of mannotriose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of mannotriose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900327 ! regulation of mannotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001095 ! mannotriose transport +relationship: positively_regulates GO:2001095 ! mannotriose transport +created_by: tt +creation_date: 2012-04-06T01:50:22Z + +[Term] +id: GO:1900330 +name: regulation of methane biosynthetic process from trimethylamine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001130 ! methane biosynthetic process from trimethylamine +relationship: regulates GO:2001130 ! methane biosynthetic process from trimethylamine +created_by: tt +creation_date: 2012-04-06T01:53:03Z + +[Term] +id: GO:1900331 +name: negative regulation of methane biosynthetic process from trimethylamine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from trimethylamine" NARROW [GOC:TermGenie] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900330 ! regulation of methane biosynthetic process from trimethylamine +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001130 ! methane biosynthetic process from trimethylamine +relationship: negatively_regulates GO:2001130 ! methane biosynthetic process from trimethylamine +created_by: tt +creation_date: 2012-04-06T01:53:12Z + +[Term] +id: GO:1900332 +name: positive regulation of methane biosynthetic process from trimethylamine +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from trimethylamine" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from trimethylamine" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900330 ! regulation of methane biosynthetic process from trimethylamine +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001130 ! methane biosynthetic process from trimethylamine +relationship: positively_regulates GO:2001130 ! methane biosynthetic process from trimethylamine +created_by: tt +creation_date: 2012-04-06T01:53:20Z + +[Term] +id: GO:1900333 +name: regulation of methane biosynthetic process from 3-(methylthio)propionic acid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +relationship: regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +created_by: tt +creation_date: 2012-04-06T01:56:13Z + +[Term] +id: GO:1900334 +name: negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from 3-(methylthio)propionic acid" NARROW [GOC:TermGenie] +is_a: GO:0045922 ! negative regulation of fatty acid metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1900333 ! regulation of methane biosynthetic process from 3-(methylthio)propionic acid +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +relationship: negatively_regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +created_by: tt +creation_date: 2012-04-06T01:56:23Z + +[Term] +id: GO:1900335 +name: positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from 3-(methylthio)propionic acid" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from 3-(methylthio)propionic acid" EXACT [GOC:TermGenie] +is_a: GO:0045923 ! positive regulation of fatty acid metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900333 ! regulation of methane biosynthetic process from 3-(methylthio)propionic acid +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +relationship: positively_regulates GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid +created_by: tt +creation_date: 2012-04-06T01:56:31Z + +[Term] +id: GO:1900336 +name: regulation of methane biosynthetic process from carbon monoxide +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +relationship: regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +created_by: tt +creation_date: 2012-04-06T02:03:15Z + +[Term] +id: GO:1900337 +name: negative regulation of methane biosynthetic process from carbon monoxide +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from carbon monoxide" NARROW [GOC:TermGenie] +is_a: GO:1900336 ! regulation of methane biosynthetic process from carbon monoxide +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +relationship: negatively_regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +created_by: tt +creation_date: 2012-04-06T02:03:24Z + +[Term] +id: GO:1900338 +name: positive regulation of methane biosynthetic process from carbon monoxide +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from carbon monoxide" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from carbon monoxide" EXACT [GOC:TermGenie] +is_a: GO:1900336 ! regulation of methane biosynthetic process from carbon monoxide +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +relationship: positively_regulates GO:2001134 ! methane biosynthetic process from carbon monoxide +created_by: tt +creation_date: 2012-04-06T02:03:33Z + +[Term] +id: GO:1900339 +name: regulation of methane biosynthetic process from formic acid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001127 ! methane biosynthetic process from formic acid +relationship: regulates GO:2001127 ! methane biosynthetic process from formic acid +created_by: tt +creation_date: 2012-04-06T02:04:53Z + +[Term] +id: GO:1900340 +name: negative regulation of methane biosynthetic process from formic acid +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from formic acid" NARROW [GOC:TermGenie] +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900339 ! regulation of methane biosynthetic process from formic acid +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001127 ! methane biosynthetic process from formic acid +relationship: negatively_regulates GO:2001127 ! methane biosynthetic process from formic acid +created_by: tt +creation_date: 2012-04-06T02:05:03Z + +[Term] +id: GO:1900341 +name: positive regulation of methane biosynthetic process from formic acid +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from formic acid" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from formic acid" EXACT [GOC:TermGenie] +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900339 ! regulation of methane biosynthetic process from formic acid +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001127 ! methane biosynthetic process from formic acid +relationship: positively_regulates GO:2001127 ! methane biosynthetic process from formic acid +created_by: tt +creation_date: 2012-04-06T02:05:11Z + +[Term] +id: GO:1900342 +name: regulation of methane biosynthetic process from dimethyl sulfide +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +relationship: regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +created_by: tt +creation_date: 2012-04-06T02:06:38Z + +[Term] +id: GO:1900343 +name: negative regulation of methane biosynthetic process from dimethyl sulfide +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from dimethyl sulfide" NARROW [GOC:TermGenie] +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1900342 ! regulation of methane biosynthetic process from dimethyl sulfide +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +relationship: negatively_regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +created_by: tt +creation_date: 2012-04-06T02:06:47Z + +[Term] +id: GO:1900344 +name: positive regulation of methane biosynthetic process from dimethyl sulfide +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from dimethyl sulfide" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from dimethyl sulfide" EXACT [GOC:TermGenie] +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900342 ! regulation of methane biosynthetic process from dimethyl sulfide +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +relationship: positively_regulates GO:2001131 ! methane biosynthetic process from dimethyl sulfide +created_by: tt +creation_date: 2012-04-06T02:06:56Z + +[Term] +id: GO:1900345 +name: regulation of methane biosynthetic process from methanethiol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001133 ! methane biosynthetic process from methanethiol +relationship: regulates GO:2001133 ! methane biosynthetic process from methanethiol +created_by: tt +creation_date: 2012-04-06T02:09:49Z + +[Term] +id: GO:1900346 +name: negative regulation of methane biosynthetic process from methanethiol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from methanethiol" NARROW [GOC:TermGenie] +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1900345 ! regulation of methane biosynthetic process from methanethiol +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001133 ! methane biosynthetic process from methanethiol +relationship: negatively_regulates GO:2001133 ! methane biosynthetic process from methanethiol +created_by: tt +creation_date: 2012-04-06T02:09:58Z + +[Term] +id: GO:1900347 +name: positive regulation of methane biosynthetic process from methanethiol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from methanethiol" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from methanethiol" EXACT [GOC:TermGenie] +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900345 ! regulation of methane biosynthetic process from methanethiol +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001133 ! methane biosynthetic process from methanethiol +relationship: positively_regulates GO:2001133 ! methane biosynthetic process from methanethiol +created_by: tt +creation_date: 2012-04-06T02:10:06Z + +[Term] +id: GO:1900348 +name: regulation of methane biosynthetic process from methylamine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0043457 ! regulation of cellular respiration +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001128 ! methane biosynthetic process from methylamine +relationship: regulates GO:2001128 ! methane biosynthetic process from methylamine +created_by: tt +creation_date: 2012-04-06T02:11:54Z + +[Term] +id: GO:1900349 +name: negative regulation of methane biosynthetic process from methylamine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +synonym: "down-regulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +synonym: "downregulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +synonym: "inhibition of methane biosynthetic process from methylamine" NARROW [GOC:TermGenie] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900348 ! regulation of methane biosynthetic process from methylamine +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +is_a: GO:1901856 ! negative regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001128 ! methane biosynthetic process from methylamine +relationship: negatively_regulates GO:2001128 ! methane biosynthetic process from methylamine +created_by: tt +creation_date: 2012-04-06T02:12:04Z + +[Term] +id: GO:1900350 +name: positive regulation of methane biosynthetic process from methylamine +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methane biosynthetic process from methylamine" NARROW [GOC:TermGenie] +synonym: "up regulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +synonym: "up-regulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +synonym: "upregulation of methane biosynthetic process from methylamine" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900348 ! regulation of methane biosynthetic process from methylamine +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +is_a: GO:1901857 ! positive regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001128 ! methane biosynthetic process from methylamine +relationship: positively_regulates GO:2001128 ! methane biosynthetic process from methylamine +created_by: tt +creation_date: 2012-04-06T02:12:12Z + +[Term] +id: GO:1900351 +name: regulation of methanofuran biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042068 ! regulation of pteridine metabolic process +is_a: GO:1900354 ! regulation of methanofuran metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001120 ! methanofuran biosynthetic process +relationship: regulates GO:2001120 ! methanofuran biosynthetic process +created_by: tt +creation_date: 2012-04-06T02:13:51Z + +[Term] +id: GO:1900352 +name: negative regulation of methanofuran biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of methanofuran biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045863 ! negative regulation of pteridine metabolic process +is_a: GO:1900351 ! regulation of methanofuran biosynthetic process +is_a: GO:1900355 ! negative regulation of methanofuran metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001120 ! methanofuran biosynthetic process +relationship: negatively_regulates GO:2001120 ! methanofuran biosynthetic process +created_by: tt +creation_date: 2012-04-06T02:14:00Z + +[Term] +id: GO:1900353 +name: positive regulation of methanofuran biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of methanofuran biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methanofuran biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of methanofuran biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045864 ! positive regulation of pteridine metabolic process +is_a: GO:1900351 ! regulation of methanofuran biosynthetic process +is_a: GO:1900356 ! positive regulation of methanofuran metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001120 ! methanofuran biosynthetic process +relationship: positively_regulates GO:2001120 ! methanofuran biosynthetic process +created_by: tt +creation_date: 2012-04-06T02:14:09Z + +[Term] +id: GO:1900354 +name: regulation of methanofuran metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methanofuran metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001119 ! methanofuran metabolic process +relationship: regulates GO:2001119 ! methanofuran metabolic process +created_by: tt +creation_date: 2012-04-06T02:15:44Z + +[Term] +id: GO:1900355 +name: negative regulation of methanofuran metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of methanofuran metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900354 ! regulation of methanofuran metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001119 ! methanofuran metabolic process +relationship: negatively_regulates GO:2001119 ! methanofuran metabolic process +created_by: tt +creation_date: 2012-04-06T02:15:53Z + +[Term] +id: GO:1900356 +name: positive regulation of methanofuran metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methanofuran metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanofuran metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of methanofuran metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methanofuran metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900354 ! regulation of methanofuran metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001119 ! methanofuran metabolic process +relationship: positively_regulates GO:2001119 ! methanofuran metabolic process +created_by: tt +creation_date: 2012-04-06T02:16:01Z + +[Term] +id: GO:1900357 +name: regulation of nigerotriose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nigerotriose transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001091 ! nigerotriose transport +relationship: regulates GO:2001091 ! nigerotriose transport +created_by: tt +creation_date: 2012-04-06T02:18:06Z + +[Term] +id: GO:1900358 +name: negative regulation of nigerotriose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of nigerotriose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of nigerotriose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of nigerotriose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of nigerotriose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900357 ! regulation of nigerotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001091 ! nigerotriose transport +relationship: negatively_regulates GO:2001091 ! nigerotriose transport +created_by: tt +creation_date: 2012-04-06T02:18:21Z + +[Term] +id: GO:1900359 +name: positive regulation of nigerotriose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nigerotriose transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of nigerotriose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of nigerotriose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of nigerotriose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of nigerotriose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900357 ! regulation of nigerotriose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001091 ! nigerotriose transport +relationship: positively_regulates GO:2001091 ! nigerotriose transport +created_by: tt +creation_date: 2012-04-06T02:18:29Z + +[Term] +id: GO:1900360 +name: regulation of pentasaccharide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pentasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001100 ! pentasaccharide transport +relationship: regulates GO:2001100 ! pentasaccharide transport +created_by: tt +creation_date: 2012-04-06T02:19:27Z + +[Term] +id: GO:1900361 +name: negative regulation of pentasaccharide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of pentasaccharide transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of pentasaccharide transport" EXACT [GOC:TermGenie] +synonym: "downregulation of pentasaccharide transport" EXACT [GOC:TermGenie] +synonym: "inhibition of pentasaccharide transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1900360 ! regulation of pentasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001100 ! pentasaccharide transport +relationship: negatively_regulates GO:2001100 ! pentasaccharide transport +created_by: tt +creation_date: 2012-04-06T02:19:36Z + +[Term] +id: GO:1900362 +name: positive regulation of pentasaccharide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pentasaccharide transport." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of pentasaccharide transport" NARROW [GOC:TermGenie] +synonym: "up regulation of pentasaccharide transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of pentasaccharide transport" EXACT [GOC:TermGenie] +synonym: "upregulation of pentasaccharide transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1900360 ! regulation of pentasaccharide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001100 ! pentasaccharide transport +relationship: positively_regulates GO:2001100 ! pentasaccharide transport +created_by: tt +creation_date: 2012-04-06T02:19:44Z + +[Term] +id: GO:1900363 +name: regulation of mRNA polyadenylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA polyadenylation." [GOC:se, GOC:TermGenie, PMID:15121841] +synonym: "regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +is_a: GO:0031440 ! regulation of mRNA 3'-end processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006378 ! mRNA polyadenylation +relationship: regulates GO:0006378 ! mRNA polyadenylation +created_by: pr +creation_date: 2012-04-12T04:36:21Z + +[Term] +id: GO:1900364 +name: negative regulation of mRNA polyadenylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation." [GOC:se, GOC:TermGenie, PMID:15121841] +synonym: "down regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "down regulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "downregulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "downregulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "inhibition of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA polyadenylation" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA polyadenylylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +is_a: GO:0031441 ! negative regulation of mRNA 3'-end processing +is_a: GO:1900363 ! regulation of mRNA polyadenylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006378 ! mRNA polyadenylation +relationship: negatively_regulates GO:0006378 ! mRNA polyadenylation +created_by: pr +creation_date: 2012-04-12T04:36:31Z + +[Term] +id: GO:1900365 +name: positive regulation of mRNA polyadenylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation." [GOC:se, GOC:TermGenie, PMID:15121841] +synonym: "activation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "activation of mRNA polyadenylation" NARROW [GOC:TermGenie] +synonym: "activation of mRNA polyadenylylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "up regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "up regulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +synonym: "upregulation of cleavage and polyadenylylation specificity factor activity" NARROW [GOC:TermGenie] +synonym: "upregulation of mRNA polyadenylation" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA polyadenylylation" EXACT [GOC:TermGenie] +is_a: GO:0031442 ! positive regulation of mRNA 3'-end processing +is_a: GO:1900363 ! regulation of mRNA polyadenylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006378 ! mRNA polyadenylation +relationship: positively_regulates GO:0006378 ! mRNA polyadenylation +created_by: pr +creation_date: 2012-04-12T04:36:39Z + +[Term] +id: GO:1900366 +name: negative regulation of defense response to insect +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] +synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "inhibition of defense response to insect" NARROW [GOC:TermGenie] +synonym: "inhibition of physiological defense response to insect" NARROW [GOC:TermGenie] +synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "susceptibility to insect" RELATED [] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:2000068 ! regulation of defense response to insect +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002213 ! defense response to insect +relationship: negatively_regulates GO:0002213 ! defense response to insect +created_by: dhl +creation_date: 2012-04-12T04:44:00Z + +[Term] +id: GO:1900367 +name: positive regulation of defense response to insect +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] +synonym: "activation of defense response to insect" NARROW [GOC:TermGenie] +synonym: "activation of physiological defense response to insect" NARROW [GOC:TermGenie] +synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] +synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie] +synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:2000068 ! regulation of defense response to insect +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002213 ! defense response to insect +relationship: positively_regulates GO:0002213 ! defense response to insect +created_by: dhl +creation_date: 2012-04-12T04:44:10Z + +[Term] +id: GO:1900368 +name: regulation of RNA interference +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA interference." [GOC:kmv, GOC:TermGenie, PMID:22412382] +synonym: "regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "regulation of RNAi" EXACT [GOC:TermGenie] +is_a: GO:0060147 ! regulation of posttranscriptional gene silencing +is_a: GO:0060966 ! regulation of gene silencing by RNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016246 ! RNA interference +relationship: regulates GO:0016246 ! RNA interference +created_by: kmv +creation_date: 2012-04-13T08:28:39Z + +[Term] +id: GO:1900369 +name: negative regulation of RNA interference +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference." [GOC:kmv, GOC:TermGenie, PMID:22412382] +synonym: "down regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "down regulation of RNAi" EXACT [GOC:TermGenie] +synonym: "down-regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNAi" EXACT [GOC:TermGenie] +synonym: "downregulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "downregulation of RNAi" EXACT [GOC:TermGenie] +synonym: "inhibition of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA interference" NARROW [GOC:TermGenie] +synonym: "inhibition of RNAi" EXACT [GOC:TermGenie] +synonym: "negative regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNAi" EXACT [GOC:TermGenie] +is_a: GO:0060149 ! negative regulation of posttranscriptional gene silencing +is_a: GO:0060967 ! negative regulation of gene silencing by RNA +is_a: GO:1900368 ! regulation of RNA interference +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016246 ! RNA interference +relationship: negatively_regulates GO:0016246 ! RNA interference +created_by: kmv +creation_date: 2012-04-13T08:28:50Z + +[Term] +id: GO:1900370 +name: positive regulation of RNA interference +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA interference." [GOC:kmv, GOC:TermGenie, PMID:22412382] +synonym: "activation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "activation of RNA interference" NARROW [GOC:TermGenie] +synonym: "activation of RNAi" EXACT [GOC:TermGenie] +synonym: "positive regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNAi" EXACT [GOC:TermGenie] +synonym: "up regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "up regulation of RNAi" EXACT [GOC:TermGenie] +synonym: "up-regulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNAi" EXACT [GOC:TermGenie] +synonym: "upregulation of posttranscriptional gene silencing by siRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA interference" EXACT [GOC:TermGenie] +synonym: "upregulation of RNAi" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0060148 ! positive regulation of posttranscriptional gene silencing +is_a: GO:1900368 ! regulation of RNA interference +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016246 ! RNA interference +relationship: positively_regulates GO:0016246 ! RNA interference +created_by: kmv +creation_date: 2012-04-13T08:29:00Z + +[Term] +id: GO:1900371 +name: regulation of purine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes." [GOC:go_curators, GOC:TermGenie] +synonym: "regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030808 ! regulation of nucleotide biosynthetic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006164 ! purine nucleotide biosynthetic process +relationship: regulates GO:0006164 ! purine nucleotide biosynthetic process +created_by: krc +creation_date: 2012-04-17T12:32:07Z + +[Term] +id: GO:1900372 +name: negative regulation of purine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes." [GOC:go_curators, GOC:TermGenie] +synonym: "down regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of purine nucleotide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "inhibition of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030809 ! negative regulation of nucleotide biosynthetic process +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +is_a: GO:1900543 ! negative regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006164 ! purine nucleotide biosynthetic process +relationship: negatively_regulates GO:0006164 ! purine nucleotide biosynthetic process +created_by: krc +creation_date: 2012-04-17T12:32:27Z + +[Term] +id: GO:1900373 +name: positive regulation of purine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes." [GOC:go_curators, GOC:TermGenie] +synonym: "activation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030810 ! positive regulation of nucleotide biosynthetic process +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +is_a: GO:1900544 ! positive regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006164 ! purine nucleotide biosynthetic process +relationship: positively_regulates GO:0006164 ! purine nucleotide biosynthetic process +created_by: krc +creation_date: 2012-04-17T12:32:37Z + +[Term] +id: GO:1900374 +name: obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching." [GOC:go_curators, GOC:TermGenie, PMID:8804308] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of mating type switching by regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-04-17T12:39:56Z + +[Term] +id: GO:1900375 +name: obsolete positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process." [GOC:go_curators, GOC:TermGenie, PMID:2004420] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of inositol formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-04-17T12:45:48Z + +[Term] +id: GO:1900376 +name: regulation of secondary metabolite biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0043455 ! regulation of secondary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044550 ! secondary metabolite biosynthetic process +relationship: regulates GO:0044550 ! secondary metabolite biosynthetic process +created_by: di +creation_date: 2012-04-17T01:55:23Z + +[Term] +id: GO:1900377 +name: negative regulation of secondary metabolite biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process +relationship: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process +created_by: di +creation_date: 2012-04-17T01:55:32Z + +[Term] +id: GO:1900378 +name: positive regulation of secondary metabolite biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process +relationship: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process +created_by: di +creation_date: 2012-04-17T01:55:41Z + +[Term] +id: GO:1900379 +name: regulation of asperthecin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036184 ! asperthecin biosynthetic process +relationship: regulates GO:0036184 ! asperthecin biosynthetic process +created_by: di +creation_date: 2012-04-17T01:58:27Z + +[Term] +id: GO:1900380 +name: negative regulation of asperthecin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of asperthecin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900379 ! regulation of asperthecin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036184 ! asperthecin biosynthetic process +relationship: negatively_regulates GO:0036184 ! asperthecin biosynthetic process +created_by: di +creation_date: 2012-04-17T01:58:37Z + +[Term] +id: GO:1900381 +name: positive regulation of asperthecin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of asperthecin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "activation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperthecin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of asperthecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of asperthecin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of asperthecin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of asperthecin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900379 ! regulation of asperthecin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036184 ! asperthecin biosynthetic process +relationship: positively_regulates GO:0036184 ! asperthecin biosynthetic process +created_by: di +creation_date: 2012-04-17T01:58:45Z + +[Term] +id: GO:1900382 +name: obsolete regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process." [GOC:mah, GOC:TermGenie, PMID:16874521] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of thiamin biosynthetic process by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of thiamine anabolism by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of thiamine biosynthesis by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of thiamine formation by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of thiamine synthesis by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-17T04:05:24Z + +[Term] +id: GO:1900383 +name: regulation of synaptic plasticity by receptor localization to synapse +namespace: biological_process +def: "Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse." [GOC:kmv, GOC:TermGenie, PMID:22464329] +synonym: "regulation of synaptic plasticity by receptor localisation to synapse" EXACT [GOC:TermGenie] +is_a: GO:0097120 ! receptor localization to synapse +created_by: kmv +creation_date: 2012-04-17T04:44:37Z + +[Term] +id: GO:1900384 +name: regulation of flavonol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of flavonol biosynthetic process." [GOC:TermGenie] +is_a: GO:0009962 ! regulation of flavonoid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051555 ! flavonol biosynthetic process +relationship: regulates GO:0051555 ! flavonol biosynthetic process +created_by: tb +creation_date: 2012-04-17T10:22:49Z + +[Term] +id: GO:1900385 +name: negative regulation of flavonol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of flavonol biosynthetic process" NARROW [GOC:TermGenie] +is_a: GO:0009964 ! negative regulation of flavonoid biosynthetic process +is_a: GO:1900384 ! regulation of flavonol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051555 ! flavonol biosynthetic process +relationship: negatively_regulates GO:0051555 ! flavonol biosynthetic process +created_by: tb +creation_date: 2012-04-17T10:22:59Z + +[Term] +id: GO:1900386 +name: positive regulation of flavonol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process." [GOC:TermGenie] +synonym: "activation of flavonol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of flavonol biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0009963 ! positive regulation of flavonoid biosynthetic process +is_a: GO:1900384 ! regulation of flavonol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051555 ! flavonol biosynthetic process +relationship: positively_regulates GO:0051555 ! flavonol biosynthetic process +created_by: tb +creation_date: 2012-04-17T10:23:09Z + +[Term] +id: GO:1900387 +name: obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion." [GOC:BHF, GOC:TermGenie, PMID:15737616] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: pr +creation_date: 2012-04-18T12:01:19Z + +[Term] +id: GO:1900388 +name: obsolete regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of vesicle-mediated transport." [GOC:mah, GOC:TermGenie, PMID:18622392] +comment: This term was made obsolete because there is no evidence that vesicle-mediated transport is regulated transcriptionally. +synonym: "regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter" EXACT [] +is_obsolete: true +created_by: mah +creation_date: 2012-04-18T03:52:29Z + +[Term] +id: GO:1900389 +name: obsolete regulation of glucose import by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import." [GOC:mah, GOC:TermGenie, PMID:18622392] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of glucose uptake by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-18T03:52:43Z + +[Term] +id: GO:1900391 +name: obsolete regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling." [GOC:mah, GOC:TermGenie, PMID:15448137] +comment: The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter. +synonym: "regulation of cAMP-mediated signalling by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14279 xsd:anyURI +is_obsolete: true +created_by: mah +creation_date: 2012-04-18T04:19:39Z + +[Term] +id: GO:1900392 +name: obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport." [GOC:mah, GOC:TermGenie, PMID:17446861] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2012-04-18T04:20:25Z + +[Term] +id: GO:1900394 +name: regulation of kojic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001317 ! kojic acid biosynthetic process +relationship: regulates GO:2001317 ! kojic acid biosynthetic process +created_by: di +creation_date: 2012-04-18T04:19:53Z + +[Term] +id: GO:1900395 +name: negative regulation of kojic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "down regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "downregulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "inhibition of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of kojic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "inhibition of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900394 ! regulation of kojic acid biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001317 ! kojic acid biosynthetic process +relationship: negatively_regulates GO:2001317 ! kojic acid biosynthetic process +created_by: di +creation_date: 2012-04-18T04:20:03Z + +[Term] +id: GO:1900396 +name: positive regulation of kojic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "activation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "activation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "activation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "activation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "activation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of kojic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "activation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "up regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of kojic acid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of C6H6O4 anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of C6H6O4 biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of C6H6O4 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of C6H6O4 formation" RELATED [GOC:TermGenie] +synonym: "upregulation of C6H6O4 synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of kojic acid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of kojic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of kojic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of kojic acid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of kojic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900394 ! regulation of kojic acid biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001317 ! kojic acid biosynthetic process +relationship: positively_regulates GO:2001317 ! kojic acid biosynthetic process +created_by: di +creation_date: 2012-04-18T04:20:11Z + +[Term] +id: GO:1900397 +name: regulation of pyrimidine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process." [GOC:TermGenie] +synonym: "regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030808 ! regulation of nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +relationship: regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +created_by: jh +creation_date: 2012-04-19T01:05:31Z + +[Term] +id: GO:1900398 +name: negative regulation of pyrimidine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of pyrimidine nucleotide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "inhibition of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030809 ! negative regulation of nucleotide biosynthetic process +is_a: GO:1900397 ! regulation of pyrimidine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +relationship: negatively_regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +created_by: jh +creation_date: 2012-04-19T01:05:41Z + +[Term] +id: GO:1900399 +name: positive regulation of pyrimidine nucleotide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process." [GOC:TermGenie] +synonym: "activation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "activation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of pyrimidine nucleotide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "activation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine nucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine nucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine nucleotide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine nucleotide formation" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine nucleotide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030810 ! positive regulation of nucleotide biosynthetic process +is_a: GO:1900397 ! regulation of pyrimidine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +relationship: positively_regulates GO:0006221 ! pyrimidine nucleotide biosynthetic process +created_by: jh +creation_date: 2012-04-19T01:05:50Z + +[Term] +id: GO:1900400 +name: regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +alt_id: GO:1900393 +def: "A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import." [GOC:mah, GOC:TermGenie, PMID:18622392] +synonym: "regulation of iron import by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of iron ion import by regulation of transcription from RNA polymerase II promoter" RELATED [] +synonym: "regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter" BROAD [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0034756 ! regulation of iron ion transport +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0006366 ! transcription by RNA polymerase II +intersection_of: regulates GO:0033212 ! iron import into cell +relationship: regulates GO:0033212 ! iron import into cell +creation_date: 2012-04-20T02:34:12Z + +[Term] +id: GO:1900402 +name: obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process." [GOC:mah, GOC:TermGenie, PMID:16408318] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T02:45:27Z + +[Term] +id: GO:1900403 +name: obsolete negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process." [GOC:mah, GOC:TermGenie, PMID:17446861] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular amino acid anabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular amino acid biosynthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular amino acid formation by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular amino acid synthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T02:45:42Z + +[Term] +id: GO:1900404 +name: positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair." [GOC:mah, GOC:TermGenie, PMID:20299455] +synonym: "activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045739 ! positive regulation of DNA repair +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: positively_regulates GO:0100026 ! positive regulation of DNA repair by transcription from RNA polymerase II promoter +relationship: positively_regulates GO:0100026 ! positive regulation of DNA repair by transcription from RNA polymerase II promoter +created_by: mah +creation_date: 2012-04-20T02:45:56Z + +[Term] +id: GO:1900405 +name: obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cell separation after cytokinesis." [GOC:mah, GOC:TermGenie, PMID:10491317, PMID:12665550] +synonym: "regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T02:46:10Z + +[Term] +id: GO:1900406 +name: obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion." [GOC:mah, GOC:TermGenie, PMID:1112904] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T02:46:24Z + +[Term] +id: GO:1900407 +name: regulation of cellular response to oxidative stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] +synonym: "regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +is_a: GO:0080135 ! regulation of cellular response to stress +is_a: GO:1902882 ! regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034599 ! cellular response to oxidative stress +relationship: regulates GO:0034599 ! cellular response to oxidative stress +created_by: mah +creation_date: 2012-04-20T03:30:52Z + +[Term] +id: GO:1900408 +name: negative regulation of cellular response to oxidative stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] +synonym: "down regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "down regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "down-regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "downregulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "inhibition of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1900407 ! regulation of cellular response to oxidative stress +is_a: GO:1902883 ! negative regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034599 ! cellular response to oxidative stress +relationship: negatively_regulates GO:0034599 ! cellular response to oxidative stress +created_by: mah +creation_date: 2012-04-20T03:31:05Z + +[Term] +id: GO:1900409 +name: positive regulation of cellular response to oxidative stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie] +synonym: "activation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "up regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "up-regulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of adaptive response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "upregulation of cellular response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1900407 ! regulation of cellular response to oxidative stress +is_a: GO:1902884 ! positive regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034599 ! cellular response to oxidative stress +relationship: positively_regulates GO:0034599 ! cellular response to oxidative stress +created_by: mah +creation_date: 2012-04-20T03:31:16Z + +[Term] +id: GO:1900410 +name: obsolete regulation of histone modification by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone modification." [GOC:mah, GOC:TermGenie] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:35:08Z + +[Term] +id: GO:1900411 +name: obsolete regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone acetylation." [GOC:mah, GOC:TermGenie, PMID:15218150] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:35:22Z + +[Term] +id: GO:1900412 +name: obsolete regulation of histone methylation by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone methylation." [GOC:mah, GOC:TermGenie, PMID:15218150] +comment: This term was obsoleted because it describes a process that does not exist. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:35:36Z + +[Term] +id: GO:1900413 +name: obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process." [GOC:mah, GOC:TermGenie, PMID:16537923] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:41:58Z + +[Term] +id: GO:1900414 +name: obsolete regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis." [GOC:mah, GOC:TermGenie, PMID:15509866] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:42:13Z + +[Term] +id: GO:1900415 +name: obsolete regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis." [GOC:mah, GOC:TermGenie, PMID:15509866] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of chitin- and beta-glucan-containing cell wall biogenesis by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:42:27Z + +[Term] +id: GO:1900416 +name: obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process." [GOC:mah, GOC:TermGenie, PMID:15173185] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:42:41Z + +[Term] +id: GO:1900417 +name: obsolete negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport." [GOC:mah, GOC:TermGenie, PMID:20404084] +comment: The term was obsoleted because it is better represented by a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2012-04-20T03:42:55Z + +[Term] +id: GO:1900418 +name: obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process." [GOC:curators, GOC:TermGenie, PMID:17573544] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-04-20T10:13:58Z + +[Term] +id: GO:1900419 +name: regulation of cellular alcohol catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process." [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044109 ! cellular alcohol catabolic process +relationship: regulates GO:0044109 ! cellular alcohol catabolic process +created_by: krc +creation_date: 2012-04-20T10:21:18Z + +[Term] +id: GO:1900420 +name: negative regulation of cellular alcohol catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process." [GOC:TermGenie] +synonym: "down regulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular alcohol catabolic process" NARROW [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900419 ! regulation of cellular alcohol catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044109 ! cellular alcohol catabolic process +relationship: negatively_regulates GO:0044109 ! cellular alcohol catabolic process +created_by: krc +creation_date: 2012-04-20T10:21:28Z + +[Term] +id: GO:1900421 +name: positive regulation of cellular alcohol catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process." [GOC:TermGenie] +synonym: "activation of cellular alcohol catabolic process" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular alcohol catabolic process" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900419 ! regulation of cellular alcohol catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044109 ! cellular alcohol catabolic process +relationship: positively_regulates GO:0044109 ! cellular alcohol catabolic process +created_by: krc +creation_date: 2012-04-20T10:21:46Z + +[Term] +id: GO:1900422 +name: obsolete positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process." [GOC:curators, GOC:TermGenie, PMID:3305157, PMID:8221926] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-04-24T05:13:25Z + +[Term] +id: GO:1900423 +name: obsolete positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching." [GOC:TermGenie, PMID:8804308] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of mating type switching by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "stimulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: krc +creation_date: 2012-04-24T05:50:51Z + +[Term] +id: GO:1900424 +name: regulation of defense response to bacterium +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] +synonym: "regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "regulation of defense response to bacteria" EXACT [GOC:TermGenie] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042742 ! defense response to bacterium +relationship: regulates GO:0042742 ! defense response to bacterium +created_by: dhl +creation_date: 2012-04-24T10:12:43Z + +[Term] +id: GO:1900425 +name: negative regulation of defense response to bacterium +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] +synonym: "down regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "down regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "down regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "down regulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "down regulation of defense response to bacterium" EXACT [GOC:TermGenie] +synonym: "down-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "down-regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "down-regulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "down-regulation of defense response to bacterium" EXACT [GOC:TermGenie] +synonym: "downregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "downregulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "downregulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "downregulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "downregulation of defense response to bacterium" EXACT [GOC:TermGenie] +synonym: "inhibition of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "inhibition of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "inhibition of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "inhibition of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "inhibition of defense response to bacterium" NARROW [GOC:TermGenie] +synonym: "negative regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "negative regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "negative regulation of defense response to bacteria" EXACT [GOC:TermGenie] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042742 ! defense response to bacterium +relationship: negatively_regulates GO:0042742 ! defense response to bacterium +created_by: dhl +creation_date: 2012-04-24T10:12:54Z + +[Term] +id: GO:1900426 +name: positive regulation of defense response to bacterium +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] +synonym: "activation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "activation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "activation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "activation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "activation of defense response to bacterium" NARROW [GOC:TermGenie] +synonym: "positive regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "positive regulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "up regulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of defense response to bacterium" EXACT [GOC:TermGenie] +synonym: "up-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "up-regulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "up-regulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "up-regulation of defense response to bacterium" EXACT [GOC:TermGenie] +synonym: "upregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "upregulation of defence response to bacteria" EXACT [GOC:TermGenie] +synonym: "upregulation of defence response to bacterium" EXACT [GOC:TermGenie] +synonym: "upregulation of defense response to bacteria" EXACT [GOC:TermGenie] +synonym: "upregulation of defense response to bacterium" EXACT [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042742 ! defense response to bacterium +relationship: positively_regulates GO:0042742 ! defense response to bacterium +created_by: dhl +creation_date: 2012-04-24T10:13:13Z + +[Term] +id: GO:1900427 +name: obsolete regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress." [GOC:mah, GOC:TermGenie, PMID:10348908] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of adaptive response to oxidative stress by regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: mah +creation_date: 2012-04-25T09:11:41Z + +[Term] +id: GO:1900428 +name: regulation of filamentous growth of a population of unicellular organisms +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms." [GOC:di, GOC:TermGenie] +is_a: GO:0010570 ! regulation of filamentous growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +relationship: regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: di +creation_date: 2012-04-25T05:53:33Z + +[Term] +id: GO:1900429 +name: negative regulation of filamentous growth of a population of unicellular organisms +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms" NARROW [GOC:TermGenie] +is_a: GO:0060258 ! negative regulation of filamentous growth +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +relationship: negatively_regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: di +creation_date: 2012-04-25T05:53:43Z + +[Term] +id: GO:1900430 +name: positive regulation of filamentous growth of a population of unicellular organisms +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms" EXACT [GOC:TermGenie] +is_a: GO:0090033 ! positive regulation of filamentous growth +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +relationship: positively_regulates GO:0044182 ! filamentous growth of a population of unicellular organisms +created_by: di +creation_date: 2012-04-25T05:53:52Z + +[Term] +id: GO:1900431 +name: regulation of filamentous growth of a population of unicellular organisms in response to heat +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat." [GOC:di, GOC:TermGenie] +is_a: GO:0080134 ! regulation of response to stress +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +relationship: regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +created_by: di +creation_date: 2012-04-25T05:54:05Z + +[Term] +id: GO:1900432 +name: negative regulation of filamentous growth of a population of unicellular organisms in response to heat +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to heat" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900429 ! negative regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900431 ! regulation of filamentous growth of a population of unicellular organisms in response to heat +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +relationship: negatively_regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +created_by: di +creation_date: 2012-04-25T05:54:15Z + +[Term] +id: GO:1900433 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to heat +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to heat" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to heat" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900431 ! regulation of filamentous growth of a population of unicellular organisms in response to heat +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +relationship: positively_regulates GO:0036168 ! filamentous growth of a population of unicellular organisms in response to heat +created_by: di +creation_date: 2012-04-25T05:54:23Z + +[Term] +id: GO:1900434 +name: regulation of filamentous growth of a population of unicellular organisms in response to starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation." [GOC:di, GOC:TermGenie] +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080134 ! regulation of response to stress +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036170 ! filamentous growth of a population of unicellular organisms in response to starvation +relationship: regulates GO:0036170 ! filamentous growth of a population of unicellular organisms in response to starvation +created_by: di +creation_date: 2012-04-25T05:54:46Z + +[Term] +id: GO:1900435 +name: obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation." [GOC:di, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to starvation" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: di +creation_date: 2012-04-25T05:54:56Z + +[Term] +id: GO:1900436 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to starvation" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to starvation" EXACT [GOC:TermGenie] +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900434 ! regulation of filamentous growth of a population of unicellular organisms in response to starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036170 ! filamentous growth of a population of unicellular organisms in response to starvation +relationship: positively_regulates GO:0036170 ! filamentous growth of a population of unicellular organisms in response to starvation +created_by: di +creation_date: 2012-04-25T05:55:05Z + +[Term] +id: GO:1900437 +name: regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus." [GOC:di, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +relationship: regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +created_by: di +creation_date: 2012-04-25T05:55:17Z + +[Term] +id: GO:1900438 +name: negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to chemical stimulus" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900429 ! negative regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900437 ! regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +relationship: negatively_regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +created_by: di +creation_date: 2012-04-25T05:55:26Z + +[Term] +id: GO:1900439 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900437 ! regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +relationship: positively_regulates GO:0036171 ! filamentous growth of a population of unicellular organisms in response to chemical stimulus +created_by: di +creation_date: 2012-04-25T05:55:35Z + +[Term] +id: GO:1900440 +name: regulation of filamentous growth of a population of unicellular organisms in response to neutral pH +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH." [GOC:di, GOC:TermGenie] +is_a: GO:1900741 ! regulation of filamentous growth of a population of unicellular organisms in response to pH +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +relationship: regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +created_by: di +creation_date: 2012-04-25T05:55:48Z + +[Term] +id: GO:1900441 +name: negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to neutral pH" NARROW [GOC:TermGenie] +is_a: GO:1900440 ! regulation of filamentous growth of a population of unicellular organisms in response to neutral pH +is_a: GO:1900742 ! negative regulation of filamentous growth of a population of unicellular organisms in response to pH +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +relationship: negatively_regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +created_by: di +creation_date: 2012-04-25T05:55:57Z + +[Term] +id: GO:1900442 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to neutral pH" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH" EXACT [GOC:TermGenie] +is_a: GO:1900440 ! regulation of filamentous growth of a population of unicellular organisms in response to neutral pH +is_a: GO:1900743 ! positive regulation of filamentous growth of a population of unicellular organisms in response to pH +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +relationship: positively_regulates GO:0036178 ! filamentous growth of a population of unicellular organisms in response to neutral pH +created_by: di +creation_date: 2012-04-25T05:56:06Z + +[Term] +id: GO:1900443 +name: regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus." [GOC:di, GOC:TermGenie] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +relationship: regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +created_by: di +creation_date: 2012-04-25T05:56:18Z + +[Term] +id: GO:1900444 +name: negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to biotic stimulus" NARROW [GOC:TermGenie] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:1900429 ! negative regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900443 ! regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +relationship: negatively_regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +created_by: di +creation_date: 2012-04-25T05:56:27Z + +[Term] +id: GO:1900445 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus" EXACT [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900443 ! regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +relationship: positively_regulates GO:0036180 ! filamentous growth of a population of unicellular organisms in response to biotic stimulus +created_by: di +creation_date: 2012-04-25T05:56:35Z + +[Term] +id: GO:1900446 +name: obsolete negative regulation of tRNA transcription from RNA polymerase III promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter." [GOC:sart, GOC:TermGenie] +comment: The reason for obsoletion is that there is no specific regulator for negatively regulating tRNA transcription which is separable from general negative regulation of transcription from RNA polymerase III. +synonym: "down regulation of tRNA transcription from Pol III promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of tRNA transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA transcription from Pol III promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA transcription from Pol III promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of tRNA transcription from Pol III promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of tRNA transcription from RNA polymerase III promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of tRNA transcription from Pol III promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: sart +creation_date: 2012-04-26T05:28:34Z + +[Term] +id: GO:1900447 +name: regulation of cell morphogenesis involved in phenotypic switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:di, GOC:TermGenie] +synonym: "negative regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "negative regulation of cell shape and cell size of phenotypic switching" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell shape and cell size of phenotypic switching" RELATED [GOC:TermGenie] +synonym: "regulation of cell morphogenesis of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "regulation of cell morphogenesis of phenotypic switching" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape and cell size of phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "regulation of cell shape and cell size of phenotypic switching" RELATED [GOC:TermGenie] +is_a: GO:0022604 ! regulation of cell morphogenesis +intersection_of: GO:0022604 ! regulation of cell morphogenesis +intersection_of: part_of GO:0036166 ! phenotypic switching +relationship: part_of GO:0036166 ! phenotypic switching +created_by: di +creation_date: 2012-04-27T02:43:32Z + +[Term] +id: GO:1900448 +name: obsolete regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: jh +creation_date: 2012-04-27T02:57:38Z + +[Term] +id: GO:1900449 +name: regulation of glutamate receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007215 ! glutamate receptor signaling pathway +relationship: regulates GO:0007215 ! glutamate receptor signaling pathway +created_by: rl +creation_date: 2012-04-27T03:45:43Z + +[Term] +id: GO:1900450 +name: negative regulation of glutamate receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of glutamate receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900449 ! regulation of glutamate receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007215 ! glutamate receptor signaling pathway +relationship: negatively_regulates GO:0007215 ! glutamate receptor signaling pathway +created_by: rl +creation_date: 2012-04-27T03:45:53Z + +[Term] +id: GO:1900451 +name: positive regulation of glutamate receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "activation of glutamate receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "activation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamate receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamate signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamate signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900449 ! regulation of glutamate receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007215 ! glutamate receptor signaling pathway +relationship: positively_regulates GO:0007215 ! glutamate receptor signaling pathway +created_by: rl +creation_date: 2012-04-27T03:46:03Z + +[Term] +id: GO:1900452 +name: regulation of long-term synaptic depression +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of long term synaptic depression." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "regulation of long term synaptic depression" EXACT [] +synonym: "regulation of LTD" RELATED [GOC:TermGenie] +is_a: GO:0048167 ! regulation of synaptic plasticity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060292 ! long-term synaptic depression +relationship: regulates GO:0060292 ! long-term synaptic depression +created_by: rl +creation_date: 2012-04-27T03:54:58Z + +[Term] +id: GO:1900453 +name: negative regulation of long-term synaptic depression +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "down regulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "down regulation of LTD" RELATED [GOC:TermGenie] +synonym: "down-regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "down-regulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "down-regulation of LTD" RELATED [GOC:TermGenie] +synonym: "downregulation of long term depression" BROAD [GOC:TermGenie] +synonym: "downregulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "downregulation of LTD" RELATED [GOC:TermGenie] +synonym: "inhibition of long term depression" BROAD [GOC:TermGenie] +synonym: "inhibition of long term synaptic depression" NARROW [GOC:TermGenie] +synonym: "inhibition of LTD" RELATED [GOC:TermGenie] +synonym: "negative regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "negative regulation of long term synaptic depression" RELATED [] +synonym: "negative regulation of LTD" RELATED [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:1900452 ! regulation of long-term synaptic depression +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060292 ! long-term synaptic depression +relationship: negatively_regulates GO:0060292 ! long-term synaptic depression +created_by: rl +creation_date: 2012-04-27T03:55:14Z + +[Term] +id: GO:1900454 +name: positive regulation of long-term synaptic depression +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of long term synaptic depression." [GOC:BHF, GOC:TermGenie] +synonym: "activation of long term depression" BROAD [GOC:TermGenie] +synonym: "activation of long term synaptic depression" NARROW [GOC:TermGenie] +synonym: "activation of LTD" RELATED [GOC:TermGenie] +synonym: "positive regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "positive regulation of long term synaptic depression" EXACT [] +synonym: "positive regulation of LTD" RELATED [GOC:TermGenie] +synonym: "up regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "up regulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "up regulation of LTD" RELATED [GOC:TermGenie] +synonym: "up-regulation of long term depression" BROAD [GOC:TermGenie] +synonym: "up-regulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "up-regulation of LTD" RELATED [GOC:TermGenie] +synonym: "upregulation of long term depression" BROAD [GOC:TermGenie] +synonym: "upregulation of long term synaptic depression" EXACT [GOC:TermGenie] +synonym: "upregulation of LTD" RELATED [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1900452 ! regulation of long-term synaptic depression +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060292 ! long-term synaptic depression +relationship: positively_regulates GO:0060292 ! long-term synaptic depression +created_by: rl +creation_date: 2012-04-27T03:55:23Z + +[Term] +id: GO:1900456 +name: obsolete regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:10373537, PMID:10591965, PMID:12024013, PMID:15466424, PMID:16568252, PMID:8710886, PMID:9811878, PMID:9987114] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of colony morphology by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter" EXACT [] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T05:42:03Z + +[Term] +id: GO:1900457 +name: regulation of brassinosteroid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway." [GOC:TermGenie, PMID:21855796] +synonym: "regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009742 ! brassinosteroid mediated signaling pathway +relationship: regulates GO:0009742 ! brassinosteroid mediated signaling pathway +created_by: dhl +creation_date: 2012-05-01T06:12:04Z + +[Term] +id: GO:1900458 +name: negative regulation of brassinosteroid mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway." [GOC:TermGenie, PMID:21855796] +synonym: "down regulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "down-regulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "downregulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "inhibition of brassinosteroid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900457 ! regulation of brassinosteroid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009742 ! brassinosteroid mediated signaling pathway +relationship: negatively_regulates GO:0009742 ! brassinosteroid mediated signaling pathway +created_by: dhl +creation_date: 2012-05-01T06:12:13Z + +[Term] +id: GO:1900459 +name: positive regulation of brassinosteroid mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway." [GOC:TermGenie, PMID:21855796] +synonym: "activation of brassinosteroid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "positive regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "up regulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "up-regulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +synonym: "upregulation of brassinosteroid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of brassinosteroid mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900457 ! regulation of brassinosteroid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009742 ! brassinosteroid mediated signaling pathway +relationship: positively_regulates GO:0009742 ! brassinosteroid mediated signaling pathway +created_by: dhl +creation_date: 2012-05-01T06:12:23Z + +[Term] +id: GO:1900460 +name: obsolete negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:12024013, PMID:15466424, PMID:9811878] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of colony morphology by negative regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T06:09:17Z + +[Term] +id: GO:1900461 +name: positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:11046133, PMID:8710886, PMID:9987114] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:2000222 ! positive regulation of pseudohyphal growth +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: positively_regulates GO:0007124 ! pseudohyphal growth +created_by: dgf +creation_date: 2012-05-01T07:01:40Z + +[Term] +id: GO:1900462 +name: obsolete negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:12024012, PMID:9811878] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T07:01:54Z + +[Term] +id: GO:1900463 +name: negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:12509465, PMID:17023428] +synonym: "negative regulation of cellular response to alkalinity by negative regulation of transcription from RNA polymerase II promoter" BROAD [] +synonym: "negative regulation of cellular response to basic pH by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1900068 ! negative regulation of cellular response to alkaline pH +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0071469 ! cellular response to alkaline pH +created_by: dgf +creation_date: 2012-05-01T07:22:50Z + +[Term] +id: GO:1900464 +name: negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:16278455] +synonym: "negative regulation of cellular response to hyperosmotic salt stress by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1900070 ! negative regulation of cellular hyperosmotic salinity response +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0071475 ! cellular hyperosmotic salinity response +created_by: dgf +creation_date: 2012-05-01T07:29:19Z + +[Term] +id: GO:1900465 +name: obsolete negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:19233144, PMID:8455631] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of arginine breakdown by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of arginine catabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of arginine degradation by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T07:38:01Z + +[Term] +id: GO:1900466 +name: obsolete positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:19233144, PMID:8455631] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of arginine formation by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T07:38:14Z + +[Term] +id: GO:1900467 +name: obsolete regulation of cellular potassium ion homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis." [GOC:dgf, GOC:TermGenie, PMID:20412803] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of cellular potassium ion homeostasis" EXACT [] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T07:48:07Z + +[Term] +id: GO:1900468 +name: regulation of phosphatidylserine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +synonym: "regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +is_a: GO:0150178 ! regulation of phosphatidylserine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006659 ! phosphatidylserine biosynthetic process +relationship: regulates GO:0006659 ! phosphatidylserine biosynthetic process +created_by: dgf +creation_date: 2012-05-01T08:01:01Z + +[Term] +id: GO:1900469 +name: negative regulation of phosphatidylserine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +synonym: "down regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +is_a: GO:0150180 ! negative regulation of phosphatidylserine metabolic process +is_a: GO:1900468 ! regulation of phosphatidylserine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006659 ! phosphatidylserine biosynthetic process +relationship: negatively_regulates GO:0006659 ! phosphatidylserine biosynthetic process +created_by: dgf +creation_date: 2012-05-01T08:01:11Z + +[Term] +id: GO:1900470 +name: positive regulation of phosphatidylserine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +synonym: "activation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +is_a: GO:0150179 ! positive regulation of phosphatidylserine metabolic process +is_a: GO:1900468 ! regulation of phosphatidylserine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006659 ! phosphatidylserine biosynthetic process +relationship: positively_regulates GO:0006659 ! phosphatidylserine biosynthetic process +created_by: dgf +creation_date: 2012-05-01T08:01:19Z + +[Term] +id: GO:1900471 +name: obsolete negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of inositol anabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol formation by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of inositol synthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of myo-inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of myo-inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of vitamin Bh biosynthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of vitamin Bh biosynthetic process by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T08:13:23Z + +[Term] +id: GO:1900472 +name: obsolete positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of phosphatidylcholine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylcholine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylcholine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylcholine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T08:13:36Z + +[Term] +id: GO:1900473 +name: obsolete negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8056324] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of phosphatidylcholine anabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylcholine biosynthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylcholine formation by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylcholine synthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T08:13:51Z + +[Term] +id: GO:1900474 +name: obsolete negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8625408, PMID:8625409] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T08:33:18Z + +[Term] +id: GO:1900477 +name: negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:19841732] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:2000134 ! negative regulation of G1/S transition of mitotic cell cycle +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: dgf +creation_date: 2012-05-01T09:01:04Z + +[Term] +id: GO:1900478 +name: obsolete positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:7601277, PMID:7891681] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up-regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "upregulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-01T09:08:04Z + +[Term] +id: GO:1900480 +name: regulation of diacylglycerol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process." [GOC:TermGenie] +synonym: "regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006651 ! diacylglycerol biosynthetic process +relationship: regulates GO:0006651 ! diacylglycerol biosynthetic process +created_by: al +creation_date: 2012-05-02T10:08:59Z + +[Term] +id: GO:1900481 +name: negative regulation of diacylglycerol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of diacylglycerol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1900480 ! regulation of diacylglycerol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006651 ! diacylglycerol biosynthetic process +relationship: negatively_regulates GO:0006651 ! diacylglycerol biosynthetic process +created_by: al +creation_date: 2012-05-02T10:09:09Z + +[Term] +id: GO:1900482 +name: positive regulation of diacylglycerol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process." [GOC:TermGenie] +synonym: "activation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of diacylglycerol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "activation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1900480 ! regulation of diacylglycerol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006651 ! diacylglycerol biosynthetic process +relationship: positively_regulates GO:0006651 ! diacylglycerol biosynthetic process +created_by: al +creation_date: 2012-05-02T10:09:18Z + +[Term] +id: GO:1900483 +name: regulation of protein targeting to vacuolar membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane." [GOC:TermGenie] +is_a: GO:0090313 ! regulation of protein targeting to membrane +is_a: GO:1903335 ! regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044395 ! protein targeting to vacuolar membrane +relationship: regulates GO:0044395 ! protein targeting to vacuolar membrane +created_by: al +creation_date: 2012-05-02T10:13:23Z + +[Term] +id: GO:1900484 +name: negative regulation of protein targeting to vacuolar membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane." [GOC:TermGenie] +synonym: "down regulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of protein targeting to vacuolar membrane" NARROW [GOC:TermGenie] +is_a: GO:0090315 ! negative regulation of protein targeting to membrane +is_a: GO:1900483 ! regulation of protein targeting to vacuolar membrane +is_a: GO:1903336 ! negative regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044395 ! protein targeting to vacuolar membrane +relationship: negatively_regulates GO:0044395 ! protein targeting to vacuolar membrane +created_by: al +creation_date: 2012-05-02T10:13:33Z + +[Term] +id: GO:1900485 +name: positive regulation of protein targeting to vacuolar membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane." [GOC:TermGenie] +synonym: "activation of protein targeting to vacuolar membrane" NARROW [GOC:TermGenie] +synonym: "up regulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein targeting to vacuolar membrane" EXACT [GOC:TermGenie] +is_a: GO:0090314 ! positive regulation of protein targeting to membrane +is_a: GO:1900483 ! regulation of protein targeting to vacuolar membrane +is_a: GO:1903337 ! positive regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044395 ! protein targeting to vacuolar membrane +relationship: positively_regulates GO:0044395 ! protein targeting to vacuolar membrane +created_by: al +creation_date: 2012-05-02T10:13:41Z + +[Term] +id: GO:1900486 +name: positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway." [GOC:TermGenie] +synonym: "activation of Ac-MVA pathway" EXACT [GOC:TermGenie] +synonym: "activation of acetate-mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "activation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "activation of isopentenyl diphosphate biosynthetic process, mevalonate pathway" NARROW [GOC:TermGenie] +synonym: "activation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "activation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of Ac-MVA pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of acetate-mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Ac-MVA pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of acetate-mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ac-MVA pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetate-mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Ac-MVA pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of acetate-mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:TermGenie] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +is_a: GO:1900544 ! positive regulation of purine nucleotide metabolic process +is_a: GO:2001210 ! regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +relationship: positively_regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +created_by: al +creation_date: 2012-05-02T10:46:46Z + +[Term] +id: GO:1900487 +name: regulation of [2Fe-2S] cluster assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly." [GOC:mengo_curators, GOC:pr, GOC:TermGenie] +synonym: "regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1903329 ! regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044571 ! [2Fe-2S] cluster assembly +relationship: regulates GO:0044571 ! [2Fe-2S] cluster assembly +created_by: tt +creation_date: 2012-05-02T01:22:22Z + +[Term] +id: GO:1900488 +name: negative regulation of [2Fe-2S] cluster assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of 2Fe-2S cluster assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of [2Fe-2S] cluster assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1900487 ! regulation of [2Fe-2S] cluster assembly +is_a: GO:1903330 ! negative regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044571 ! [2Fe-2S] cluster assembly +relationship: negatively_regulates GO:0044571 ! [2Fe-2S] cluster assembly +created_by: tt +creation_date: 2012-05-02T01:22:32Z + +[Term] +id: GO:1900489 +name: positive regulation of [2Fe-2S] cluster assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly." [GOC:mengo_curators, GOC:pr, GOC:TermGenie] +synonym: "activation of 2Fe-2S cluster assembly" NARROW [GOC:TermGenie] +synonym: "activation of [2Fe-2S] cluster assembly" NARROW [GOC:TermGenie] +synonym: "activation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of 2Fe-2S cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of [2Fe-2S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of [2Fe-2S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1900487 ! regulation of [2Fe-2S] cluster assembly +is_a: GO:1903331 ! positive regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044571 ! [2Fe-2S] cluster assembly +relationship: positively_regulates GO:0044571 ! [2Fe-2S] cluster assembly +created_by: tt +creation_date: 2012-05-02T01:22:40Z + +[Term] +id: GO:1900490 +name: positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity." [GOC:TermGenie] +synonym: "activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [GOC:TermGenie] +synonym: "activation of HMG-CoA reductase activity" BROAD [GOC:TermGenie] +synonym: "activation of hydroxymethylglutaryl-CoA reductase (NADPH) activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [GOC:TermGenie] +synonym: "positive regulation of HMG-CoA reductase activity" BROAD [GOC:TermGenie] +synonym: "up regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [GOC:TermGenie] +synonym: "up regulation of HMG-CoA reductase activity" BROAD [GOC:TermGenie] +synonym: "up regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [GOC:TermGenie] +synonym: "up-regulation of HMG-CoA reductase activity" BROAD [GOC:TermGenie] +synonym: "up-regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [GOC:TermGenie] +synonym: "upregulation of HMG-CoA reductase activity" BROAD [GOC:TermGenie] +synonym: "upregulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity" EXACT [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:2001215 ! regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +relationship: positively_regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +created_by: al +creation_date: 2012-05-02T03:01:43Z + +[Term] +id: GO:1900491 +name: regulation of [4Fe-4S] cluster assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly." [GOC:mengo_curators, GOC:pr, GOC:TermGenie] +synonym: "regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1903329 ! regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044572 ! [4Fe-4S] cluster assembly +relationship: regulates GO:0044572 ! [4Fe-4S] cluster assembly +created_by: tt +creation_date: 2012-05-02T03:48:49Z + +[Term] +id: GO:1900492 +name: negative regulation of [4Fe-4S] cluster assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly." [GOC:mengo_curators, GOC:pr, GOC:TermGenie] +synonym: "down regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of 4Fe-4S cluster assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of [4Fe-4S] cluster assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1900491 ! regulation of [4Fe-4S] cluster assembly +is_a: GO:1903330 ! negative regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044572 ! [4Fe-4S] cluster assembly +relationship: negatively_regulates GO:0044572 ! [4Fe-4S] cluster assembly +created_by: tt +creation_date: 2012-05-02T03:49:00Z + +[Term] +id: GO:1900493 +name: positive regulation of [4Fe-4S] cluster assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly." [GOC:mengo_curators, GOC:pr, GOC:TermGenie] +synonym: "activation of 4Fe-4S cluster assembly" NARROW [GOC:TermGenie] +synonym: "activation of [4Fe-4S] cluster assembly" NARROW [GOC:TermGenie] +synonym: "activation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of 4Fe-4S cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of [4Fe-4S] cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of [4Fe-4S] cluster biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:1900491 ! regulation of [4Fe-4S] cluster assembly +is_a: GO:1903331 ! positive regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044572 ! [4Fe-4S] cluster assembly +relationship: positively_regulates GO:0044572 ! [4Fe-4S] cluster assembly +created_by: tt +creation_date: 2012-05-02T03:49:10Z + +[Term] +id: GO:1900494 +name: regulation of butyryl-CoA biosynthetic process from acetyl-CoA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +is_a: GO:0050812 ! regulation of acyl-CoA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +relationship: regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +created_by: tt +creation_date: 2012-05-02T03:51:38Z + +[Term] +id: GO:1900495 +name: negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "down regulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA biosynthetic process from acetyl-CoA" NARROW [GOC:TermGenie] +synonym: "negative regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:1900372 ! negative regulation of purine nucleotide biosynthetic process +is_a: GO:1900494 ! regulation of butyryl-CoA biosynthetic process from acetyl-CoA +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +relationship: negatively_regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +created_by: tt +creation_date: 2012-05-02T03:51:49Z + +[Term] +id: GO:1900496 +name: positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "activation of butyryl-CoA biosynthetic process from acetyl-CoA" NARROW [GOC:TermGenie] +synonym: "positive regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA biosynthesis from acetyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA biosynthetic process from acetyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:1900373 ! positive regulation of purine nucleotide biosynthetic process +is_a: GO:1900494 ! regulation of butyryl-CoA biosynthetic process from acetyl-CoA +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +relationship: positively_regulates GO:0044579 ! butyryl-CoA biosynthetic process from acetyl-CoA +created_by: tt +creation_date: 2012-05-02T03:51:58Z + +[Term] +id: GO:1900497 +name: regulation of butyryl-CoA catabolic process to butanol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0033121 ! regulation of purine nucleotide catabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +relationship: regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +created_by: tt +creation_date: 2012-05-02T03:53:20Z + +[Term] +id: GO:1900498 +name: negative regulation of butyryl-CoA catabolic process to butanol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "down regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA catabolic process to butanol" NARROW [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "negative regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +is_a: GO:0033122 ! negative regulation of purine nucleotide catabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045922 ! negative regulation of fatty acid metabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:1900497 ! regulation of butyryl-CoA catabolic process to butanol +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +relationship: negatively_regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +created_by: tt +creation_date: 2012-05-02T03:53:31Z + +[Term] +id: GO:1900499 +name: positive regulation of butyryl-CoA catabolic process to butanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of butyryl-CoA catabolic process to butanol" NARROW [GOC:TermGenie] +synonym: "activation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "positive regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA catabolic process to butanol" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA catabolism to butanol" EXACT [GOC:TermGenie] +is_a: GO:0033123 ! positive regulation of purine nucleotide catabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045923 ! positive regulation of fatty acid metabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:1900497 ! regulation of butyryl-CoA catabolic process to butanol +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +relationship: positively_regulates GO:0044582 ! butyryl-CoA catabolic process to butanol +created_by: tt +creation_date: 2012-05-02T03:53:40Z + +[Term] +id: GO:1900500 +name: regulation of butyryl-CoA catabolic process to butyrate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +is_a: GO:0033121 ! regulation of purine nucleotide catabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +relationship: regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +created_by: tt +creation_date: 2012-05-02T03:56:19Z + +[Term] +id: GO:1900501 +name: negative regulation of butyryl-CoA catabolic process to butyrate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "down regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "down-regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "downregulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA catabolic process to butyrate" NARROW [GOC:TermGenie] +synonym: "inhibition of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "negative regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +is_a: GO:0033122 ! negative regulation of purine nucleotide catabolic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:1900500 ! regulation of butyryl-CoA catabolic process to butyrate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +relationship: negatively_regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +created_by: tt +creation_date: 2012-05-02T03:56:30Z + +[Term] +id: GO:1900502 +name: positive regulation of butyryl-CoA catabolic process to butyrate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of butyryl-CoA catabolic process to butyrate" NARROW [GOC:TermGenie] +synonym: "activation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "positive regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "up regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "up-regulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA catabolic process to butyrate" EXACT [GOC:TermGenie] +synonym: "upregulation of butyryl-CoA catabolism to butyrate" EXACT [GOC:TermGenie] +is_a: GO:0033123 ! positive regulation of purine nucleotide catabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:1900500 ! regulation of butyryl-CoA catabolic process to butyrate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +relationship: positively_regulates GO:0044581 ! butyryl-CoA catabolic process to butyrate +created_by: tt +creation_date: 2012-05-02T03:56:40Z + +[Term] +id: GO:1900503 +name: regulation of cellulosome assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellulosome assembly." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044575 ! cellulosome assembly +relationship: regulates GO:0044575 ! cellulosome assembly +created_by: tt +creation_date: 2012-05-02T03:58:15Z + +[Term] +id: GO:1900504 +name: negative regulation of cellulosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of cellulosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellulosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cellulosome assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of cellulosome assembly" NARROW [GOC:TermGenie] +is_a: GO:1900503 ! regulation of cellulosome assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044575 ! cellulosome assembly +relationship: negatively_regulates GO:0044575 ! cellulosome assembly +created_by: tt +creation_date: 2012-05-02T03:58:26Z + +[Term] +id: GO:1900505 +name: positive regulation of cellulosome assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellulosome assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of cellulosome assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of cellulosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellulosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of cellulosome assembly" EXACT [GOC:TermGenie] +is_a: GO:1900503 ! regulation of cellulosome assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044575 ! cellulosome assembly +relationship: positively_regulates GO:0044575 ! cellulosome assembly +created_by: tt +creation_date: 2012-05-02T03:58:35Z + +[Term] +id: GO:1900506 +name: regulation of iron-sulfur-molybdenum cofactor assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +relationship: regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +created_by: tt +creation_date: 2012-05-02T04:02:16Z + +[Term] +id: GO:1900507 +name: negative regulation of iron-sulfur-molybdenum cofactor assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of iron-sulfur-molybdenum cofactor assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1900506 ! regulation of iron-sulfur-molybdenum cofactor assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +relationship: negatively_regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +created_by: tt +creation_date: 2012-05-02T04:02:27Z + +[Term] +id: GO:1900508 +name: positive regulation of iron-sulfur-molybdenum cofactor assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "activation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "activation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "activation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "activation of iron-sulfur-molybdenum cofactor assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of FeMoco assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of FeMoco biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of iron molybdenum cofactor assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of iron molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of iron molybdenum cofactor biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of iron-sulfur-molybdenum cofactor assembly" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1900506 ! regulation of iron-sulfur-molybdenum cofactor assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +relationship: positively_regulates GO:0044593 ! iron-sulfur-molybdenum cofactor assembly +created_by: tt +creation_date: 2012-05-02T04:02:37Z + +[Term] +id: GO:1900509 +name: regulation of pentose catabolic process to ethanol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044576 ! pentose catabolic process to ethanol +relationship: regulates GO:0044576 ! pentose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:04:40Z + +[Term] +id: GO:1900510 +name: negative regulation of pentose catabolic process to ethanol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "down regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "downregulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "downregulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "inhibition of pentose catabolic process to ethanol" NARROW [GOC:TermGenie] +synonym: "inhibition of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "negative regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900509 ! regulation of pentose catabolic process to ethanol +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044576 ! pentose catabolic process to ethanol +relationship: negatively_regulates GO:0044576 ! pentose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:04:51Z + +[Term] +id: GO:1900511 +name: positive regulation of pentose catabolic process to ethanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of pentose catabolic process to ethanol" NARROW [GOC:TermGenie] +synonym: "activation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "positive regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "up regulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "up regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "upregulation of pentose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "upregulation of pentose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900509 ! regulation of pentose catabolic process to ethanol +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044576 ! pentose catabolic process to ethanol +relationship: positively_regulates GO:0044576 ! pentose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:05:01Z + +[Term] +id: GO:1900512 +name: regulation of starch utilization system complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of starch utilization system complex assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "regulation of SUS complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044574 ! starch utilization system complex assembly +relationship: regulates GO:0044574 ! starch utilization system complex assembly +created_by: tt +creation_date: 2012-05-02T04:06:44Z + +[Term] +id: GO:1900513 +name: negative regulation of starch utilization system complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "down regulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "down-regulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "downregulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "inhibition of starch utilization system complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "negative regulation of SUS complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1900512 ! regulation of starch utilization system complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044574 ! starch utilization system complex assembly +relationship: negatively_regulates GO:0044574 ! starch utilization system complex assembly +created_by: tt +creation_date: 2012-05-02T04:06:54Z + +[Term] +id: GO:1900514 +name: positive regulation of starch utilization system complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "activation of starch utilization system complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "positive regulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "up regulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "up-regulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of SUS complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of assembly of starch utilization system complex" EXACT [GOC:TermGenie] +synonym: "upregulation of starch utilization system complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of SUS complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1900512 ! regulation of starch utilization system complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044574 ! starch utilization system complex assembly +relationship: positively_regulates GO:0044574 ! starch utilization system complex assembly +created_by: tt +creation_date: 2012-05-02T04:07:04Z + +[Term] +id: GO:1900515 +name: regulation of xylose catabolic process to ethanol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:0043469 ! regulation of D-xylose catabolic process +is_a: GO:1900509 ! regulation of pentose catabolic process to ethanol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044577 ! xylose catabolic process to ethanol +relationship: regulates GO:0044577 ! xylose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:09:07Z + +[Term] +id: GO:1900516 +name: negative regulation of xylose catabolic process to ethanol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "down regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "downregulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "downregulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "inhibition of xylose catabolic process to ethanol" NARROW [GOC:TermGenie] +synonym: "inhibition of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "negative regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:1900510 ! negative regulation of pentose catabolic process to ethanol +is_a: GO:1900515 ! regulation of xylose catabolic process to ethanol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044577 ! xylose catabolic process to ethanol +relationship: negatively_regulates GO:0044577 ! xylose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:09:17Z + +[Term] +id: GO:1900517 +name: positive regulation of xylose catabolic process to ethanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of xylose catabolic process to ethanol" NARROW [GOC:TermGenie] +synonym: "activation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "positive regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "up regulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "up regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "upregulation of xylose catabolic process to ethanol" EXACT [GOC:TermGenie] +synonym: "upregulation of xylose catabolism to ethanol" EXACT [GOC:TermGenie] +is_a: GO:1900511 ! positive regulation of pentose catabolic process to ethanol +is_a: GO:1900515 ! regulation of xylose catabolic process to ethanol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044577 ! xylose catabolic process to ethanol +relationship: positively_regulates GO:0044577 ! xylose catabolic process to ethanol +created_by: tt +creation_date: 2012-05-02T04:09:26Z + +[Term] +id: GO:1900518 +name: regulation of response to pullulan +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to pullulan." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044592 ! response to pullulan +relationship: regulates GO:0044592 ! response to pullulan +created_by: tt +creation_date: 2012-05-02T04:11:58Z + +[Term] +id: GO:1900519 +name: negative regulation of response to pullulan +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to pullulan" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to pullulan" EXACT [GOC:TermGenie] +synonym: "downregulation of response to pullulan" EXACT [GOC:TermGenie] +synonym: "inhibition of response to pullulan" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900518 ! regulation of response to pullulan +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044592 ! response to pullulan +relationship: negatively_regulates GO:0044592 ! response to pullulan +created_by: tt +creation_date: 2012-05-02T04:12:09Z + +[Term] +id: GO:1900520 +name: positive regulation of response to pullulan +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to pullulan." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to pullulan" NARROW [GOC:TermGenie] +synonym: "up regulation of response to pullulan" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to pullulan" EXACT [GOC:TermGenie] +synonym: "upregulation of response to pullulan" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900518 ! regulation of response to pullulan +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044592 ! response to pullulan +relationship: positively_regulates GO:0044592 ! response to pullulan +created_by: tt +creation_date: 2012-05-02T04:12:19Z + +[Term] +id: GO:1900521 +name: regulation of response to amylopectin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to amylopectin." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044591 ! response to amylopectin +relationship: regulates GO:0044591 ! response to amylopectin +created_by: tt +creation_date: 2012-05-02T04:13:51Z + +[Term] +id: GO:1900522 +name: negative regulation of response to amylopectin +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to amylopectin" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to amylopectin" EXACT [GOC:TermGenie] +synonym: "downregulation of response to amylopectin" EXACT [GOC:TermGenie] +synonym: "inhibition of response to amylopectin" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900521 ! regulation of response to amylopectin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044591 ! response to amylopectin +relationship: negatively_regulates GO:0044591 ! response to amylopectin +created_by: tt +creation_date: 2012-05-02T04:14:01Z + +[Term] +id: GO:1900523 +name: positive regulation of response to amylopectin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to amylopectin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to amylopectin" NARROW [GOC:TermGenie] +synonym: "up regulation of response to amylopectin" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to amylopectin" EXACT [GOC:TermGenie] +synonym: "upregulation of response to amylopectin" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900521 ! regulation of response to amylopectin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044591 ! response to amylopectin +relationship: positively_regulates GO:0044591 ! response to amylopectin +created_by: tt +creation_date: 2012-05-02T04:14:11Z + +[Term] +id: GO:1900524 +name: obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:10591965, PMID:15466424, PMID:16568252] +comment: This term was obsoleted because it represents a GO-CAM. +synonym: "activation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "up regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-03T05:13:41Z + +[Term] +id: GO:1900525 +name: obsolete positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8056324, PMID:8614637] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "activation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-03T05:13:55Z + +[Term] +id: GO:1900526 +name: obsolete negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:dgf, GOC:TermGenie, PMID:8056324] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of phosphatidylserine anabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine biosynthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine formation by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine synthesis by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dgf +creation_date: 2012-05-03T05:14:10Z + +[Term] +id: GO:1900527 +name: obsolete regulation of nucleus size involved in G1 to G0 transition +namespace: biological_process +def: "OBSOLETE. Any regulation of nucleus size that is involved in G1 to G0 transition." [GOC:al, GOC:TermGenie, PMID:19366728] +comment: This term was made obsolete because it represents a phenotype. +synonym: "regulation of nuclear size involved in cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "regulation of nuclear size involved in establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear size involved in G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear size involved in G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear size involved in stationary phase" RELATED [GOC:TermGenie] +synonym: "regulation of nuclear volume involved in cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "regulation of nuclear volume involved in establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear volume involved in G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear volume involved in G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear volume involved in stationary phase" RELATED [GOC:TermGenie] +synonym: "regulation of nucleus size involved in cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "regulation of nucleus size involved in establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "regulation of nucleus size involved in G1 to G0 transition" EXACT [] +synonym: "regulation of nucleus size involved in G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of nucleus size involved in stationary phase" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T10:39:01Z + +[Term] +id: GO:1900528 +name: obsolete regulation of cell shape involved in G1 to G0 transition +namespace: biological_process +def: "OBSOLETE. Any regulation of cell shape that is involved in G1 to G0 transition." [GOC:al, GOC:TermGenie, PMID:19366728] +comment: This term was made obsolete because it represents a phenotype. +synonym: "regulation of cell shape involved in cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "regulation of cell shape involved in establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape involved in G1 to G0 transition" EXACT [] +synonym: "regulation of cell shape involved in G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape involved in stationary phase" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T10:42:45Z + +[Term] +id: GO:1900529 +name: obsolete regulation of cell shape involved in cellular response to glucose starvation +namespace: biological_process +def: "OBSOLETE. Any regulation of cell shape that is involved in cellular response to glucose starvation." [GOC:al, GOC:TermGenie, PMID:9135147] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of cell shape involved in cellular response to glucose starvation" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T01:43:38Z + +[Term] +id: GO:1900530 +name: obsolete regulation of cell shape involved in cellular response to salt stress +namespace: biological_process +def: "OBSOLETE. Any regulation of cell shape that is involved in cellular response to salt stress." [GOC:al, GOC:TermGenie, PMID:9135147] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of cell shape involved in cellular response to salt stress" EXACT [] +synonym: "regulation of cell shape of cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape of cellular response to salt stress" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape of cellular salinity response" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T01:48:01Z + +[Term] +id: GO:1900531 +name: obsolete regulation of cell shape involved in cellular response to heat +namespace: biological_process +def: "OBSOLETE. Any regulation of cell shape that is involved in cellular response to heat." [GOC:al, GOC:TermGenie, PMID:9135147] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of cell shape involved in cellular response to heat" EXACT [] +synonym: "regulation of cell shape of cellular response to heat" EXACT [GOC:TermGenie] +synonym: "regulation of cell shape of cellular response to heat stress" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T01:51:00Z + +[Term] +id: GO:1900532 +name: obsolete negative regulation of cell proliferation involved in cellular hyperosmotic response +namespace: biological_process +def: "OBSOLETE. Negative regulation of cell proliferation during cellular hyperosmotic response." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of cell proliferation of cellular HOG response" EXACT [GOC:TermGenie] +synonym: "down regulation of cell proliferation of cellular hyperosmotic response" EXACT [GOC:TermGenie] +synonym: "down regulation of cell proliferation of cellular hypertonic response" EXACT [GOC:TermGenie] +synonym: "down regulation of cell proliferation of cellular response to hypertonicity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation of cellular HOG response" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation of cellular hyperosmotic response" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation of cellular hypertonic response" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation of cellular response to hypertonicity" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation of cellular HOG response" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation of cellular hyperosmotic response" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation of cellular hypertonic response" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation of cellular response to hypertonicity" EXACT [GOC:TermGenie] +synonym: "inhibition of cell proliferation of cellular HOG response" NARROW [GOC:TermGenie] +synonym: "inhibition of cell proliferation of cellular hyperosmotic response" NARROW [GOC:TermGenie] +synonym: "inhibition of cell proliferation of cellular hypertonic response" NARROW [GOC:TermGenie] +synonym: "inhibition of cell proliferation of cellular response to hypertonicity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell proliferation involved in cellular hyperosmotic response" EXACT [] +synonym: "negative regulation of cell proliferation of cellular HOG response" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell proliferation of cellular hyperosmotic response" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell proliferation of cellular hypertonic response" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell proliferation of cellular response to hypertonicity" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-05-08T02:42:52Z + +[Term] +id: GO:1900533 +name: palmitic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving palmitic acid." [GOC:TermGenie] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +created_by: tb +creation_date: 2012-05-09T07:03:55Z + +[Term] +id: GO:1900534 +name: palmitic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of palmitic acid." [GOC:TermGenie] +is_a: GO:0042758 ! long-chain fatty acid catabolic process +is_a: GO:1900533 ! palmitic acid metabolic process +created_by: tb +creation_date: 2012-05-09T07:04:56Z + +[Term] +id: GO:1900535 +name: palmitic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of palmitic acid." [GOC:TermGenie] +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1900533 ! palmitic acid metabolic process +created_by: tb +creation_date: 2012-05-09T07:05:17Z + +[Term] +id: GO:1900536 +name: obsolete regulation of glucose homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of glucose homeostasis" EXACT [] +is_obsolete: true +created_by: hjd +creation_date: 2012-05-10T06:52:21Z + +[Term] +id: GO:1900537 +name: obsolete negative regulation of glucose homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose homeostasis." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of glucose homeostasis" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose homeostasis" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose homeostasis" EXACT [GOC:TermGenie] +synonym: "inhibition of glucose homeostasis" NARROW [GOC:TermGenie] +synonym: "negative regulation of glucose homeostasis" EXACT [] +is_obsolete: true +created_by: hjd +creation_date: 2012-05-10T06:53:14Z + +[Term] +id: GO:1900538 +name: obsolete positive regulation of glucose homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose homeostasis." [GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of glucose homeostasis" NARROW [GOC:TermGenie] +synonym: "positive regulation of glucose homeostasis" EXACT [] +synonym: "up regulation of glucose homeostasis" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose homeostasis" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose homeostasis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: hjd +creation_date: 2012-05-10T06:53:38Z + +[Term] +id: GO:1900539 +name: fumonisin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumonisin." [GOC:TermGenie] +synonym: "fumonisin metabolism" RELATED [] +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +created_by: tb +creation_date: 2012-05-11T12:53:29Z + +[Term] +id: GO:1900540 +name: fumonisin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumonisin." [GOC:TermGenie] +synonym: "fumonisin breakdown" EXACT [] +synonym: "fumonisin catabolism" EXACT [] +synonym: "fumonisin degradation" RELATED [] +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900539 ! fumonisin metabolic process +created_by: tb +creation_date: 2012-05-11T12:54:12Z + +[Term] +id: GO:1900541 +name: fumonisin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumonisin." [GOC:TermGenie] +synonym: "fumonisin anabolism" EXACT [] +synonym: "fumonisin biosynthesis" EXACT [] +synonym: "fumonisin formation" EXACT [] +synonym: "fumonisin synthesis" EXACT [] +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1900539 ! fumonisin metabolic process +created_by: tb +creation_date: 2012-05-11T12:54:37Z + +[Term] +id: GO:1900542 +name: regulation of purine nucleotide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process." [GOC:TermGenie] +synonym: "regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006140 ! regulation of nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006163 ! purine nucleotide metabolic process +relationship: regulates GO:0006163 ! purine nucleotide metabolic process +created_by: krc +creation_date: 2012-05-11T05:43:15Z + +[Term] +id: GO:1900543 +name: negative regulation of purine nucleotide metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process." [GOC:TermGenie] +synonym: "down regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "down regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "down regulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "downregulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "downregulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of purine metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of purine nucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of purine nucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045980 ! negative regulation of nucleotide metabolic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006163 ! purine nucleotide metabolic process +relationship: negatively_regulates GO:0006163 ! purine nucleotide metabolic process +created_by: krc +creation_date: 2012-05-11T05:44:21Z + +[Term] +id: GO:1900544 +name: positive regulation of purine nucleotide metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process." [GOC:TermGenie] +synonym: "activation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "activation of purine nucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of purine nucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "up regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "up regulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of purine metabolic process" NARROW [GOC:TermGenie] +synonym: "upregulation of purine metabolism" NARROW [GOC:TermGenie] +synonym: "upregulation of purine nucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of purine nucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045981 ! positive regulation of nucleotide metabolic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006163 ! purine nucleotide metabolic process +relationship: positively_regulates GO:0006163 ! purine nucleotide metabolic process +created_by: krc +creation_date: 2012-05-11T05:44:43Z + +[Term] +id: GO:1900545 +name: obsolete regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching." [GOC:di, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: di +creation_date: 2012-05-14T11:28:41Z + +[Term] +id: GO:1900546 +name: obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching." [GOC:di, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: di +creation_date: 2012-05-14T11:36:05Z + +[Term] +id: GO:1900547 +name: obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching." [GOC:di, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: di +creation_date: 2012-05-14T11:40:54Z + +[Term] +id: GO:1900548 +name: heme B catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes." [GOC:TermGenie, GOC:yaf, PMID:28352909, UniPathway:UPA00684] +synonym: "heme B breakdown" EXACT [GOC:TermGenie] +synonym: "heme B catabolism" EXACT [GOC:TermGenie] +synonym: "heme B degradation" EXACT [GOC:TermGenie] +synonym: "protoheme catabolic process" EXACT [] +synonym: "protoheme degradation" EXACT [] +xref: MetaCyc:PWY-5874 +is_a: GO:0042167 ! heme catabolic process +is_a: GO:0046492 ! heme B metabolic process +created_by: pr +creation_date: 2012-05-14T12:35:18Z + +[Term] +id: GO:1900549 +name: N',N'',N'''-triacetylfusarinine C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C." [GOC:di, GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: di +creation_date: 2012-05-15T12:59:06Z + +[Term] +id: GO:1900550 +name: N',N'',N'''-triacetylfusarinine C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C." [GOC:di, GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C breakdown" EXACT [GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C catabolism" EXACT [GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C degradation" EXACT [GOC:TermGenie] +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900549 ! N',N'',N'''-triacetylfusarinine C metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: di +creation_date: 2012-05-15T01:00:07Z + +[Term] +id: GO:1900551 +name: N',N'',N'''-triacetylfusarinine C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C." [GOC:di, GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900549 ! N',N'',N'''-triacetylfusarinine C metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: di +creation_date: 2012-05-15T01:00:58Z + +[Term] +id: GO:1900552 +name: asperfuranone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving asperfuranone." [GOC:di, GOC:TermGenie] +synonym: "asperfuranone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: di +creation_date: 2012-05-15T01:30:48Z + +[Term] +id: GO:1900553 +name: asperfuranone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of asperfuranone." [GOC:di, GOC:TermGenie] +synonym: "asperfuranone breakdown" EXACT [GOC:TermGenie] +synonym: "asperfuranone catabolism" EXACT [GOC:TermGenie] +synonym: "asperfuranone degradation" EXACT [GOC:TermGenie] +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900552 ! asperfuranone metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T01:31:35Z + +[Term] +id: GO:1900554 +name: asperfuranone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of asperfuranone." [GOC:di, GOC:TermGenie] +synonym: "asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "asperfuranone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1900552 ! asperfuranone metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process +created_by: di +creation_date: 2012-05-15T01:31:58Z + +[Term] +id: GO:1900555 +name: emericellamide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving emericellamide." [GOC:di, GOC:TermGenie] +synonym: "emericellamide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0050761 ! depsipeptide metabolic process +is_a: GO:1901334 ! lactone metabolic process +created_by: di +creation_date: 2012-05-15T01:32:19Z + +[Term] +id: GO:1900556 +name: emericellamide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of emericellamide." [GOC:di, GOC:TermGenie] +synonym: "emericellamide breakdown" EXACT [GOC:TermGenie] +synonym: "emericellamide catabolism" EXACT [GOC:TermGenie] +synonym: "emericellamide degradation" EXACT [GOC:TermGenie] +is_a: GO:0016042 ! lipid catabolic process +is_a: GO:0050762 ! depsipeptide catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900555 ! emericellamide metabolic process +is_a: GO:1901335 ! lactone catabolic process +created_by: di +creation_date: 2012-05-15T01:33:07Z + +[Term] +id: GO:1900557 +name: emericellamide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of emericellamide." [GOC:di, GOC:TermGenie] +synonym: "emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "emericellamide formation" EXACT [GOC:TermGenie] +synonym: "emericellamide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0050763 ! depsipeptide biosynthetic process +is_a: GO:1900555 ! emericellamide metabolic process +is_a: GO:1901336 ! lactone biosynthetic process +created_by: di +creation_date: 2012-05-15T01:33:31Z + +[Term] +id: GO:1900558 +name: austinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving austinol." [GOC:di, GOC:TermGenie] +synonym: "austinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: di +creation_date: 2012-05-15T06:26:58Z + +[Term] +id: GO:1900559 +name: austinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of austinol." [GOC:di, GOC:TermGenie] +synonym: "austinol breakdown" EXACT [GOC:TermGenie] +synonym: "austinol catabolism" EXACT [GOC:TermGenie] +synonym: "austinol degradation" EXACT [GOC:TermGenie] +is_a: GO:1900558 ! austinol metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: di +creation_date: 2012-05-15T06:27:22Z + +[Term] +id: GO:1900560 +name: austinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of austinol." [GOC:di, GOC:TermGenie] +synonym: "austinol anabolism" EXACT [GOC:TermGenie] +synonym: "austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "austinol formation" EXACT [GOC:TermGenie] +synonym: "austinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900558 ! austinol metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: di +creation_date: 2012-05-15T06:27:30Z + +[Term] +id: GO:1900561 +name: dehydroaustinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving dehydroaustinol." [GOC:di, GOC:TermGenie] +synonym: "dehydroaustinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: di +creation_date: 2012-05-15T06:27:35Z + +[Term] +id: GO:1900562 +name: dehydroaustinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dehydroaustinol." [GOC:di, GOC:TermGenie] +synonym: "dehydroaustinol breakdown" EXACT [GOC:TermGenie] +synonym: "dehydroaustinol catabolism" EXACT [GOC:TermGenie] +synonym: "dehydroaustinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900561 ! dehydroaustinol metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: di +creation_date: 2012-05-15T06:27:55Z + +[Term] +id: GO:1900563 +name: dehydroaustinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of dehydroaustinol." [GOC:di, GOC:TermGenie] +synonym: "dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "dehydroaustinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900561 ! dehydroaustinol metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: di +creation_date: 2012-05-15T06:28:03Z + +[Term] +id: GO:1900564 +name: chanoclavine-I metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chanoclavine-I." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I metabolism" EXACT [GOC:TermGenie] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0035836 ! ergot alkaloid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T06:30:25Z + +[Term] +id: GO:1900565 +name: chanoclavine-I catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chanoclavine-I." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I breakdown" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I catabolism" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I degradation" EXACT [GOC:TermGenie] +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900564 ! chanoclavine-I metabolic process +is_a: GO:1900806 ! ergot alkaloid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T06:30:48Z + +[Term] +id: GO:1900566 +name: chanoclavine-I biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chanoclavine-I." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0035837 ! ergot alkaloid biosynthetic process +is_a: GO:1900564 ! chanoclavine-I metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:30:55Z + +[Term] +id: GO:1900567 +name: chanoclavine-I aldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving chanoclavine-I aldehyde." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I aldehyde metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0035836 ! ergot alkaloid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T06:31:00Z + +[Term] +id: GO:1900568 +name: chanoclavine-I aldehyde catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I aldehyde breakdown" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I aldehyde catabolism" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I aldehyde degradation" EXACT [GOC:TermGenie] +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:1900567 ! chanoclavine-I aldehyde metabolic process +is_a: GO:1900806 ! ergot alkaloid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T06:31:21Z + +[Term] +id: GO:1900569 +name: chanoclavine-I aldehyde biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde." [GOC:di, GOC:TermGenie] +synonym: "chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +is_a: GO:0035837 ! ergot alkaloid biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:1900567 ! chanoclavine-I aldehyde metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:31:28Z + +[Term] +id: GO:1900570 +name: diorcinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diorcinol." [GOC:di, GOC:TermGenie] +synonym: "diorcinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +created_by: di +creation_date: 2012-05-15T06:35:01Z + +[Term] +id: GO:1900571 +name: diorcinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diorcinol." [GOC:di, GOC:TermGenie] +synonym: "diorcinol breakdown" EXACT [GOC:TermGenie] +synonym: "diorcinol catabolism" EXACT [GOC:TermGenie] +synonym: "diorcinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900570 ! diorcinol metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-05-15T06:35:22Z + +[Term] +id: GO:1900572 +name: diorcinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of diorcinol." [GOC:di, GOC:TermGenie] +synonym: "diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "diorcinol formation" EXACT [GOC:TermGenie] +synonym: "diorcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900570 ! diorcinol metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-05-15T06:35:29Z + +[Term] +id: GO:1900573 +name: emodin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving emodin." [GOC:di, GOC:TermGenie] +synonym: "emodin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: di +creation_date: 2012-05-15T06:41:44Z + +[Term] +id: GO:1900574 +name: emodin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of emodin." [GOC:di, GOC:TermGenie] +synonym: "emodin breakdown" EXACT [GOC:TermGenie] +synonym: "emodin catabolism" EXACT [GOC:TermGenie] +synonym: "emodin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900573 ! emodin metabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: di +creation_date: 2012-05-15T06:42:06Z + +[Term] +id: GO:1900575 +name: emodin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of emodin." [GOC:di, GOC:TermGenie] +synonym: "emodin anabolism" EXACT [GOC:TermGenie] +synonym: "emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "emodin formation" EXACT [GOC:TermGenie] +synonym: "emodin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900573 ! emodin metabolic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: di +creation_date: 2012-05-15T06:42:14Z + +[Term] +id: GO:1900576 +name: gerfelin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gerfelin." [GOC:di, GOC:TermGenie] +synonym: "gerfelin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: di +creation_date: 2012-05-15T06:42:19Z + +[Term] +id: GO:1900577 +name: gerfelin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gerfelin." [GOC:di, GOC:TermGenie] +synonym: "gerfelin breakdown" EXACT [GOC:TermGenie] +synonym: "gerfelin catabolism" EXACT [GOC:TermGenie] +synonym: "gerfelin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900576 ! gerfelin metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-05-15T06:42:39Z + +[Term] +id: GO:1900578 +name: gerfelin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gerfelin." [GOC:di, GOC:TermGenie] +synonym: "gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "gerfelin formation" EXACT [GOC:TermGenie] +synonym: "gerfelin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1900576 ! gerfelin metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-05-15T06:42:47Z + +[Term] +id: GO:1900579 +name: (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol." [GOC:di, GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0010685 ! tetracyclic triterpenoid metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: di +creation_date: 2012-05-15T06:47:07Z + +[Term] +id: GO:1900580 +name: (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol." [GOC:di, GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol breakdown" EXACT [GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol catabolism" EXACT [GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol degradation" EXACT [GOC:TermGenie] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0016105 ! triterpenoid catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900579 ! (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process +created_by: di +creation_date: 2012-05-15T06:47:30Z + +[Term] +id: GO:1900581 +name: (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol." [GOC:di, GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol anabolism" EXACT [GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol formation" EXACT [GOC:TermGenie] +synonym: "(17Z)-protosta-17(20),24-dien-3beta-ol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0010686 ! tetracyclic triterpenoid biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900579 ! (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process +created_by: di +creation_date: 2012-05-15T06:47:38Z + +[Term] +id: GO:1900582 +name: o-orsellinic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving o-orsellinic acid." [GOC:di, GOC:TermGenie] +synonym: "o-orsellinic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: di +creation_date: 2012-05-15T06:47:42Z + +[Term] +id: GO:1900583 +name: o-orsellinic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid." [GOC:di, GOC:TermGenie] +synonym: "o-orsellinic acid breakdown" EXACT [GOC:TermGenie] +synonym: "o-orsellinic acid catabolism" EXACT [GOC:TermGenie] +synonym: "o-orsellinic acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900582 ! o-orsellinic acid metabolic process +created_by: di +creation_date: 2012-05-15T06:48:04Z + +[Term] +id: GO:1900584 +name: o-orsellinic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of o-orsellinic acid." [GOC:di, GOC:TermGenie] +synonym: "o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900582 ! o-orsellinic acid metabolic process +created_by: di +creation_date: 2012-05-15T06:48:11Z + +[Term] +id: GO:1900585 +name: arugosin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving arugosin." [GOC:di, GOC:TermGenie] +synonym: "arugosin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: di +creation_date: 2012-05-15T06:48:15Z + +[Term] +id: GO:1900586 +name: arugosin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of arugosin." [GOC:di, GOC:TermGenie] +synonym: "arugosin breakdown" EXACT [GOC:TermGenie] +synonym: "arugosin catabolism" EXACT [GOC:TermGenie] +synonym: "arugosin degradation" EXACT [GOC:TermGenie] +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900585 ! arugosin metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: di +creation_date: 2012-05-15T06:48:37Z + +[Term] +id: GO:1900587 +name: arugosin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of arugosin." [GOC:di, GOC:TermGenie] +synonym: "arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "arugosin formation" EXACT [GOC:TermGenie] +synonym: "arugosin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900585 ! arugosin metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: di +creation_date: 2012-05-15T06:48:45Z + +[Term] +id: GO:1900588 +name: violaceol I metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving violaceol I." [GOC:di, GOC:TermGenie] +synonym: "violaceol I metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +created_by: di +creation_date: 2012-05-15T06:50:48Z + +[Term] +id: GO:1900589 +name: violaceol I catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of violaceol I." [GOC:di, GOC:TermGenie] +synonym: "violaceol I breakdown" EXACT [GOC:TermGenie] +synonym: "violaceol I catabolism" EXACT [GOC:TermGenie] +synonym: "violaceol I degradation" EXACT [GOC:TermGenie] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900588 ! violaceol I metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-05-15T06:51:09Z + +[Term] +id: GO:1900590 +name: violaceol I biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of violaceol I." [GOC:di, GOC:TermGenie] +synonym: "violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "violaceol I formation" EXACT [GOC:TermGenie] +synonym: "violaceol I synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:1900588 ! violaceol I metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-05-15T06:51:16Z + +[Term] +id: GO:1900591 +name: violaceol II metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving violaceol II." [GOC:di, GOC:TermGenie] +synonym: "violaceol II metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +created_by: di +creation_date: 2012-05-15T06:51:21Z + +[Term] +id: GO:1900592 +name: violaceol II catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of violaceol II." [GOC:di, GOC:TermGenie] +synonym: "violaceol II breakdown" EXACT [GOC:TermGenie] +synonym: "violaceol II catabolism" EXACT [GOC:TermGenie] +synonym: "violaceol II degradation" EXACT [GOC:TermGenie] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900591 ! violaceol II metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-05-15T06:51:43Z + +[Term] +id: GO:1900593 +name: violaceol II biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of violaceol II." [GOC:di, GOC:TermGenie] +synonym: "violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "violaceol II formation" EXACT [GOC:TermGenie] +synonym: "violaceol II synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:1900591 ! violaceol II metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-05-15T06:51:51Z + +[Term] +id: GO:1900594 +name: (+)-kotanin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-kotanin." [GOC:di, GOC:TermGenie] +synonym: "(+)-kotanin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T06:54:19Z + +[Term] +id: GO:1900595 +name: (+)-kotanin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-kotanin." [GOC:di, GOC:TermGenie] +synonym: "(+)-kotanin breakdown" EXACT [GOC:TermGenie] +synonym: "(+)-kotanin catabolism" EXACT [GOC:TermGenie] +synonym: "(+)-kotanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900594 ! (+)-kotanin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T06:54:40Z + +[Term] +id: GO:1900596 +name: (+)-kotanin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-kotanin." [GOC:di, GOC:TermGenie] +synonym: "(+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "(+)-kotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900594 ! (+)-kotanin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:54:47Z + +[Term] +id: GO:1900597 +name: demethylkotanin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving demethylkotanin." [GOC:di, GOC:TermGenie] +synonym: "demethylkotanin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T06:54:52Z + +[Term] +id: GO:1900598 +name: demethylkotanin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of demethylkotanin." [GOC:di, GOC:TermGenie] +synonym: "demethylkotanin breakdown" EXACT [GOC:TermGenie] +synonym: "demethylkotanin catabolism" EXACT [GOC:TermGenie] +synonym: "demethylkotanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900597 ! demethylkotanin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T06:55:14Z + +[Term] +id: GO:1900599 +name: demethylkotanin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of demethylkotanin." [GOC:di, GOC:TermGenie] +synonym: "demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "demethylkotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900597 ! demethylkotanin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:55:21Z + +[Term] +id: GO:1900600 +name: endocrocin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving endocrocin." [GOC:di, GOC:TermGenie] +synonym: "endocrocin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: di +creation_date: 2012-05-15T06:57:14Z + +[Term] +id: GO:1900601 +name: endocrocin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of endocrocin." [GOC:di, GOC:TermGenie] +synonym: "endocrocin breakdown" EXACT [GOC:TermGenie] +synonym: "endocrocin catabolism" EXACT [GOC:TermGenie] +synonym: "endocrocin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900600 ! endocrocin metabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: di +creation_date: 2012-05-15T06:57:34Z + +[Term] +id: GO:1900602 +name: endocrocin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of endocrocin." [GOC:di, GOC:TermGenie] +synonym: "endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "endocrocin formation" EXACT [GOC:TermGenie] +synonym: "endocrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900600 ! endocrocin metabolic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: di +creation_date: 2012-05-15T06:57:42Z + +[Term] +id: GO:1900603 +name: tensidol A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tensidol A." [GOC:di, GOC:TermGenie] +synonym: "tensidol A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: di +creation_date: 2012-05-15T06:57:47Z + +[Term] +id: GO:1900604 +name: tensidol A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tensidol A." [GOC:di, GOC:TermGenie] +synonym: "tensidol A breakdown" EXACT [GOC:TermGenie] +synonym: "tensidol A catabolism" EXACT [GOC:TermGenie] +synonym: "tensidol A degradation" EXACT [GOC:TermGenie] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900603 ! tensidol A metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: di +creation_date: 2012-05-15T06:58:09Z + +[Term] +id: GO:1900605 +name: tensidol A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tensidol A." [GOC:di, GOC:TermGenie] +synonym: "tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "tensidol A formation" EXACT [GOC:TermGenie] +synonym: "tensidol A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900603 ! tensidol A metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:58:16Z + +[Term] +id: GO:1900606 +name: tensidol B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tensidol B." [GOC:di, GOC:TermGenie] +synonym: "tensidol B metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T06:58:21Z + +[Term] +id: GO:1900607 +name: tensidol B catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tensidol B." [GOC:di, GOC:TermGenie] +synonym: "tensidol B breakdown" EXACT [GOC:TermGenie] +synonym: "tensidol B catabolism" EXACT [GOC:TermGenie] +synonym: "tensidol B degradation" EXACT [GOC:TermGenie] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900606 ! tensidol B metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T06:58:43Z + +[Term] +id: GO:1900608 +name: tensidol B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tensidol B." [GOC:di, GOC:TermGenie] +synonym: "tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "tensidol B formation" EXACT [GOC:TermGenie] +synonym: "tensidol B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900606 ! tensidol B metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T06:58:51Z + +[Term] +id: GO:1900609 +name: F-9775A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving F-9775A." [GOC:di, GOC:TermGenie] +synonym: "F-9775A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T07:02:27Z + +[Term] +id: GO:1900610 +name: F-9775A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of F-9775A." [GOC:di, GOC:TermGenie] +synonym: "F-9775A breakdown" EXACT [GOC:TermGenie] +synonym: "F-9775A catabolism" EXACT [GOC:TermGenie] +synonym: "F-9775A degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:1900609 ! F-9775A metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T07:02:49Z + +[Term] +id: GO:1900611 +name: F-9775A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of F-9775A." [GOC:di, GOC:TermGenie] +synonym: "F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "F-9775A formation" EXACT [GOC:TermGenie] +synonym: "F-9775A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900609 ! F-9775A metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T07:02:56Z + +[Term] +id: GO:1900612 +name: F-9775B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving F-9775B." [GOC:di, GOC:TermGenie] +synonym: "F-9775B metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: di +creation_date: 2012-05-15T07:03:01Z + +[Term] +id: GO:1900613 +name: F-9775B catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of F-9775B." [GOC:di, GOC:TermGenie] +synonym: "F-9775B breakdown" EXACT [GOC:TermGenie] +synonym: "F-9775B catabolism" EXACT [GOC:TermGenie] +synonym: "F-9775B degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:1900612 ! F-9775B metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +created_by: di +creation_date: 2012-05-15T07:03:24Z + +[Term] +id: GO:1900614 +name: F-9775B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of F-9775B." [GOC:di, GOC:TermGenie] +synonym: "F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "F-9775B formation" EXACT [GOC:TermGenie] +synonym: "F-9775B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900612 ! F-9775B metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +created_by: di +creation_date: 2012-05-15T07:03:32Z + +[Term] +id: GO:1900615 +name: emericellamide A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving emericellamide A." [GOC:di, GOC:TermGenie] +synonym: "emericellamide A metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900555 ! emericellamide metabolic process +created_by: di +creation_date: 2012-05-15T07:59:59Z + +[Term] +id: GO:1900616 +name: emericellamide A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of emericellamide A." [GOC:di, GOC:TermGenie] +synonym: "emericellamide A breakdown" EXACT [GOC:TermGenie] +synonym: "emericellamide A catabolism" EXACT [GOC:TermGenie] +synonym: "emericellamide A degradation" EXACT [GOC:TermGenie] +is_a: GO:1900556 ! emericellamide catabolic process +is_a: GO:1900615 ! emericellamide A metabolic process +created_by: di +creation_date: 2012-05-15T08:00:19Z + +[Term] +id: GO:1900617 +name: emericellamide A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of emericellamide A." [GOC:di, GOC:TermGenie] +synonym: "emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "emericellamide A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900557 ! emericellamide biosynthetic process +is_a: GO:1900615 ! emericellamide A metabolic process +created_by: di +creation_date: 2012-05-15T08:00:27Z + +[Term] +id: GO:1900618 +name: regulation of shoot system morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shoot morphogenesis." [GOC:TermGenie] +synonym: "regulation of shoot morphogenesis" EXACT [] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0048831 ! regulation of shoot system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010016 ! shoot system morphogenesis +relationship: regulates GO:0010016 ! shoot system morphogenesis +created_by: tb +creation_date: 2012-05-15T09:24:37Z + +[Term] +id: GO:1900619 +name: acetate ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie] +synonym: "acetate ester metabolism" EXACT [GOC:TermGenie] +synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622] +synonym: "acetyl ester metabolism" EXACT [CHEBI:47622] +is_a: GO:0071704 ! organic substance metabolic process +created_by: bf +creation_date: 2012-05-16T12:29:51Z + +[Term] +id: GO:1900620 +name: acetate ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596] +synonym: "acetate ester anabolism" EXACT [GOC:TermGenie] +synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "acetate ester formation" EXACT [GOC:TermGenie] +synonym: "acetate ester synthesis" EXACT [GOC:TermGenie] +synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622] +synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622] +is_a: GO:1900619 ! acetate ester metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: bf +creation_date: 2012-05-16T12:30:12Z + +[Term] +id: GO:1900621 +name: obsolete regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +namespace: biological_process +def: "OBSOLETE. Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter." [GOC:BHF, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2012-05-18T01:00:39Z + +[Term] +id: GO:1900622 +name: positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling +namespace: biological_process +def: "Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter." [GOC:bf, GOC:BHF, GOC:dgf, GOC:TermGenie, PMID:9407035, PMID:9407036] +synonym: "activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "calcineurin-dependent transcription activation" NARROW [PMID:9407036] +synonym: "calcineurin-dependent transcriptional induction" NARROW [PMID:9407035] +synonym: "calcineurin-mediated activation of transcription" NARROW [PMID:9407035] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling" EXACT [GOC:TermGenie] +is_a: GO:0019722 ! calcium-mediated signaling +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0019722 ! calcium-mediated signaling +intersection_of: positively_regulates GO:0006366 ! transcription by RNA polymerase II +created_by: bf +creation_date: 2012-05-18T01:01:04Z + +[Term] +id: GO:1900623 +name: regulation of monocyte aggregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of monocyte aggregation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070487 ! monocyte aggregation +relationship: regulates GO:0070487 ! monocyte aggregation +created_by: vk +creation_date: 2012-05-21T01:07:17Z + +[Term] +id: GO:1900624 +name: negative regulation of monocyte aggregation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "down regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "downregulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "downregulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "inhibition of monocyte aggregation" NARROW [GOC:TermGenie] +synonym: "inhibition of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "negative regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +is_a: GO:1900623 ! regulation of monocyte aggregation +is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070487 ! monocyte aggregation +relationship: negatively_regulates GO:0070487 ! monocyte aggregation +created_by: vk +creation_date: 2012-05-21T01:07:37Z + +[Term] +id: GO:1900625 +name: positive regulation of monocyte aggregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of monocyte aggregation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of monocyte aggregation" NARROW [GOC:TermGenie] +synonym: "activation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "positive regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "up regulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "up regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +synonym: "upregulation of monocyte aggregation" EXACT [GOC:TermGenie] +synonym: "upregulation of mononuclear phagocyte aggregation" EXACT [GOC:TermGenie] +is_a: GO:1900623 ! regulation of monocyte aggregation +is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070487 ! monocyte aggregation +relationship: positively_regulates GO:0070487 ! monocyte aggregation +created_by: vk +creation_date: 2012-05-21T01:07:44Z + +[Term] +id: GO:1900626 +name: regulation of arugosin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arugosin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "regulation of arugosin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900587 ! arugosin biosynthetic process +relationship: regulates GO:1900587 ! arugosin biosynthetic process +created_by: di +creation_date: 2012-05-21T05:47:39Z + +[Term] +id: GO:1900627 +name: negative regulation of arugosin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of arugosin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of arugosin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of arugosin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900626 ! regulation of arugosin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900587 ! arugosin biosynthetic process +relationship: negatively_regulates GO:1900587 ! arugosin biosynthetic process +created_by: di +creation_date: 2012-05-21T05:48:03Z + +[Term] +id: GO:1900628 +name: positive regulation of arugosin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of arugosin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "activation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of arugosin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arugosin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of arugosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arugosin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of arugosin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of arugosin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900626 ! regulation of arugosin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900587 ! arugosin biosynthetic process +relationship: positively_regulates GO:1900587 ! arugosin biosynthetic process +created_by: di +creation_date: 2012-05-21T05:48:11Z + +[Term] +id: GO:1900629 +name: methanophenazine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving methanophenazine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "methanophenazine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: tt +creation_date: 2012-05-21T06:12:07Z + +[Term] +id: GO:1900630 +name: methanophenazine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methanophenazine." [GOC:mengo_curators, GOC:TermGenie] +synonym: "methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "methanophenazine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1900629 ! methanophenazine metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: tt +creation_date: 2012-05-21T06:12:30Z + +[Term] +id: GO:1900631 +name: tridecane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tridecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "tridecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043446 ! cellular alkane metabolic process +created_by: tt +creation_date: 2012-05-21T06:41:16Z + +[Term] +id: GO:1900632 +name: tridecane biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tridecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "tridecane formation" EXACT [GOC:TermGenie] +synonym: "tridecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043447 ! alkane biosynthetic process +is_a: GO:1900631 ! tridecane metabolic process +created_by: tt +creation_date: 2012-05-21T06:41:37Z + +[Term] +id: GO:1900633 +name: pentadecane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentadecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "pentadecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043446 ! cellular alkane metabolic process +created_by: tt +creation_date: 2012-05-21T06:51:34Z + +[Term] +id: GO:1900634 +name: pentadecane biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pentadecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "pentadecane anabolism" EXACT [GOC:TermGenie] +synonym: "pentadecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "pentadecane formation" EXACT [GOC:TermGenie] +synonym: "pentadecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043447 ! alkane biosynthetic process +is_a: GO:1900633 ! pentadecane metabolic process +created_by: tt +creation_date: 2012-05-21T06:51:57Z + +[Term] +id: GO:1900635 +name: heptadecane metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heptadecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "heptadecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043446 ! cellular alkane metabolic process +created_by: tt +creation_date: 2012-05-21T07:05:01Z + +[Term] +id: GO:1900636 +name: heptadecane biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heptadecane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "heptadecane anabolism" EXACT [GOC:TermGenie] +synonym: "heptadecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "heptadecane formation" EXACT [GOC:TermGenie] +synonym: "heptadecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043447 ! alkane biosynthetic process +is_a: GO:1900635 ! heptadecane metabolic process +created_by: tt +creation_date: 2012-05-21T07:05:21Z + +[Term] +id: GO:1900637 +name: regulation of asperfuranone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900554 ! asperfuranone biosynthetic process +relationship: regulates GO:1900554 ! asperfuranone biosynthetic process +created_by: di +creation_date: 2012-05-22T03:49:55Z + +[Term] +id: GO:1900638 +name: negative regulation of asperfuranone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "down regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "downregulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of asperfuranone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "inhibition of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900637 ! regulation of asperfuranone biosynthetic process +is_a: GO:1900733 ! negative regulation of polyketide biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900554 ! asperfuranone biosynthetic process +relationship: negatively_regulates GO:1900554 ! asperfuranone biosynthetic process +created_by: di +creation_date: 2012-05-22T03:50:16Z + +[Term] +id: GO:1900639 +name: positive regulation of asperfuranone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "activation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of asperfuranone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "activation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "up regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of asperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of asperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of asperfuranone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of asperfuranone formation" EXACT [GOC:TermGenie] +synonym: "upregulation of asperfuranone synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900637 ! regulation of asperfuranone biosynthetic process +is_a: GO:1900734 ! positive regulation of polyketide biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900554 ! asperfuranone biosynthetic process +relationship: positively_regulates GO:1900554 ! asperfuranone biosynthetic process +created_by: di +creation_date: 2012-05-22T03:50:24Z + +[Term] +id: GO:1900640 +name: regulation of austinol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of austinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "regulation of austinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009889 ! regulation of biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900560 ! austinol biosynthetic process +relationship: regulates GO:1900560 ! austinol biosynthetic process +created_by: di +creation_date: 2012-05-22T03:57:33Z + +[Term] +id: GO:1900641 +name: negative regulation of austinol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of austinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of austinol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of austinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:1900640 ! regulation of austinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900560 ! austinol biosynthetic process +relationship: negatively_regulates GO:1900560 ! austinol biosynthetic process +created_by: di +creation_date: 2012-05-22T03:57:59Z + +[Term] +id: GO:1900642 +name: positive regulation of austinol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of austinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of austinol formation" EXACT [GOC:TermGenie] +synonym: "activation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of austinol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of austinol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of austinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of austinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of austinol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of austinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:1900640 ! regulation of austinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900560 ! austinol biosynthetic process +relationship: positively_regulates GO:1900560 ! austinol biosynthetic process +created_by: di +creation_date: 2012-05-22T03:58:07Z + +[Term] +id: GO:1900643 +name: regulation of chanoclavine-I biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900822 ! regulation of ergot alkaloid biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900566 ! chanoclavine-I biosynthetic process +relationship: regulates GO:1900566 ! chanoclavine-I biosynthetic process +created_by: di +creation_date: 2012-05-22T04:03:08Z + +[Term] +id: GO:1900644 +name: negative regulation of chanoclavine-I biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900643 ! regulation of chanoclavine-I biosynthetic process +is_a: GO:1900823 ! negative regulation of ergot alkaloid biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900566 ! chanoclavine-I biosynthetic process +relationship: negatively_regulates GO:1900566 ! chanoclavine-I biosynthetic process +created_by: di +creation_date: 2012-05-22T04:03:30Z + +[Term] +id: GO:1900645 +name: positive regulation of chanoclavine-I biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I formation" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900643 ! regulation of chanoclavine-I biosynthetic process +is_a: GO:1900824 ! positive regulation of ergot alkaloid biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900566 ! chanoclavine-I biosynthetic process +relationship: positively_regulates GO:1900566 ! chanoclavine-I biosynthetic process +created_by: di +creation_date: 2012-05-22T04:03:38Z + +[Term] +id: GO:1900646 +name: regulation of chanoclavine-I aldehyde biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900822 ! regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +relationship: regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +created_by: di +creation_date: 2012-05-22T04:04:38Z + +[Term] +id: GO:1900647 +name: negative regulation of chanoclavine-I aldehyde biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "down regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "downregulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I aldehyde biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "inhibition of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900646 ! regulation of chanoclavine-I aldehyde biosynthetic process +is_a: GO:1900823 ! negative regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +relationship: negatively_regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +created_by: di +creation_date: 2012-05-22T04:04:59Z + +[Term] +id: GO:1900648 +name: positive regulation of chanoclavine-I aldehyde biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I aldehyde biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "activation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "up regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I aldehyde biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I aldehyde formation" EXACT [GOC:TermGenie] +synonym: "upregulation of chanoclavine-I aldehyde synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900646 ! regulation of chanoclavine-I aldehyde biosynthetic process +is_a: GO:1900824 ! positive regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +relationship: positively_regulates GO:1900569 ! chanoclavine-I aldehyde biosynthetic process +created_by: di +creation_date: 2012-05-22T04:05:06Z + +[Term] +id: GO:1900649 +name: regulation of dehydroaustinol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900563 ! dehydroaustinol biosynthetic process +relationship: regulates GO:1900563 ! dehydroaustinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:06:03Z + +[Term] +id: GO:1900650 +name: negative regulation of dehydroaustinol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of dehydroaustinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900649 ! regulation of dehydroaustinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900563 ! dehydroaustinol biosynthetic process +relationship: negatively_regulates GO:1900563 ! dehydroaustinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:06:22Z + +[Term] +id: GO:1900651 +name: positive regulation of dehydroaustinol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of dehydroaustinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "activation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of dehydroaustinol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of dehydroaustinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of dehydroaustinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of dehydroaustinol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of dehydroaustinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900649 ! regulation of dehydroaustinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900563 ! dehydroaustinol biosynthetic process +relationship: positively_regulates GO:1900563 ! dehydroaustinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:06:30Z + +[Term] +id: GO:1900652 +name: regulation of demethylkotanin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900599 ! demethylkotanin biosynthetic process +relationship: regulates GO:1900599 ! demethylkotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:07:18Z + +[Term] +id: GO:1900653 +name: negative regulation of demethylkotanin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of demethylkotanin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900652 ! regulation of demethylkotanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900599 ! demethylkotanin biosynthetic process +relationship: negatively_regulates GO:1900599 ! demethylkotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:07:41Z + +[Term] +id: GO:1900654 +name: positive regulation of demethylkotanin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of demethylkotanin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "activation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of demethylkotanin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of demethylkotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of demethylkotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of demethylkotanin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of demethylkotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900652 ! regulation of demethylkotanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900599 ! demethylkotanin biosynthetic process +relationship: positively_regulates GO:1900599 ! demethylkotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:07:49Z + +[Term] +id: GO:1900655 +name: regulation of diorcinol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900572 ! diorcinol biosynthetic process +relationship: regulates GO:1900572 ! diorcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:08:40Z + +[Term] +id: GO:1900656 +name: negative regulation of diorcinol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of diorcinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900655 ! regulation of diorcinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900572 ! diorcinol biosynthetic process +relationship: negatively_regulates GO:1900572 ! diorcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:09:01Z + +[Term] +id: GO:1900657 +name: positive regulation of diorcinol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of diorcinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "activation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of diorcinol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of diorcinol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of diorcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of diorcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of diorcinol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of diorcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900655 ! regulation of diorcinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900572 ! diorcinol biosynthetic process +relationship: positively_regulates GO:1900572 ! diorcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:09:08Z + +[Term] +id: GO:1900658 +name: regulation of emericellamide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900557 ! emericellamide biosynthetic process +relationship: regulates GO:1900557 ! emericellamide biosynthetic process +created_by: di +creation_date: 2012-05-22T04:10:19Z + +[Term] +id: GO:1900659 +name: negative regulation of emericellamide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900658 ! regulation of emericellamide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900557 ! emericellamide biosynthetic process +relationship: negatively_regulates GO:1900557 ! emericellamide biosynthetic process +created_by: di +creation_date: 2012-05-22T04:10:44Z + +[Term] +id: GO:1900660 +name: positive regulation of emericellamide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide formation" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900658 ! regulation of emericellamide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900557 ! emericellamide biosynthetic process +relationship: positively_regulates GO:1900557 ! emericellamide biosynthetic process +created_by: di +creation_date: 2012-05-22T04:10:51Z + +[Term] +id: GO:1900661 +name: regulation of emericellamide A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900658 ! regulation of emericellamide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900617 ! emericellamide A biosynthetic process +relationship: regulates GO:1900617 ! emericellamide A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:13:07Z + +[Term] +id: GO:1900662 +name: negative regulation of emericellamide A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "down regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "inhibition of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900659 ! negative regulation of emericellamide biosynthetic process +is_a: GO:1900661 ! regulation of emericellamide A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900617 ! emericellamide A biosynthetic process +relationship: negatively_regulates GO:1900617 ! emericellamide A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:13:28Z + +[Term] +id: GO:1900663 +name: positive regulation of emericellamide A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "activation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "up regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide A anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide A biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide A formation" EXACT [GOC:TermGenie] +synonym: "upregulation of emericellamide A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900660 ! positive regulation of emericellamide biosynthetic process +is_a: GO:1900661 ! regulation of emericellamide A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900617 ! emericellamide A biosynthetic process +relationship: positively_regulates GO:1900617 ! emericellamide A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:13:36Z + +[Term] +id: GO:1900664 +name: regulation of emodin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of emodin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "regulation of emodin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900575 ! emodin biosynthetic process +relationship: regulates GO:1900575 ! emodin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:14:36Z + +[Term] +id: GO:1900665 +name: negative regulation of emodin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of emodin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of emodin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of emodin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900664 ! regulation of emodin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900575 ! emodin biosynthetic process +relationship: negatively_regulates GO:1900575 ! emodin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:14:58Z + +[Term] +id: GO:1900666 +name: positive regulation of emodin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of emodin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of emodin formation" EXACT [GOC:TermGenie] +synonym: "activation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of emodin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emodin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of emodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of emodin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of emodin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of emodin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900664 ! regulation of emodin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900575 ! emodin biosynthetic process +relationship: positively_regulates GO:1900575 ! emodin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:15:06Z + +[Term] +id: GO:1900667 +name: regulation of endocrocin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900602 ! endocrocin biosynthetic process +relationship: regulates GO:1900602 ! endocrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:16:04Z + +[Term] +id: GO:1900668 +name: negative regulation of endocrocin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of endocrocin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900667 ! regulation of endocrocin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900602 ! endocrocin biosynthetic process +relationship: negatively_regulates GO:1900602 ! endocrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:16:25Z + +[Term] +id: GO:1900669 +name: positive regulation of endocrocin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of endocrocin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "activation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endocrocin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of endocrocin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of endocrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of endocrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of endocrocin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of endocrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900667 ! regulation of endocrocin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900602 ! endocrocin biosynthetic process +relationship: positively_regulates GO:1900602 ! endocrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:16:35Z + +[Term] +id: GO:1900670 +name: regulation of F-9775A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900611 ! F-9775A biosynthetic process +relationship: regulates GO:1900611 ! F-9775A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:24:09Z + +[Term] +id: GO:1900671 +name: negative regulation of F-9775A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900670 ! regulation of F-9775A biosynthetic process +is_a: GO:1900733 ! negative regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900611 ! F-9775A biosynthetic process +relationship: negatively_regulates GO:1900611 ! F-9775A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:24:30Z + +[Term] +id: GO:1900672 +name: positive regulation of F-9775A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "activation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of F-9775A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "activation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775A synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775A anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775A biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775A formation" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900670 ! regulation of F-9775A biosynthetic process +is_a: GO:1900734 ! positive regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900611 ! F-9775A biosynthetic process +relationship: positively_regulates GO:1900611 ! F-9775A biosynthetic process +created_by: di +creation_date: 2012-05-22T04:24:37Z + +[Term] +id: GO:1900673 +name: olefin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving olefin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "olefin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: tt +creation_date: 2012-05-22T04:24:42Z + +[Term] +id: GO:1900674 +name: olefin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of olefin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "olefin anabolism" EXACT [GOC:TermGenie] +synonym: "olefin biosynthesis" EXACT [GOC:TermGenie] +synonym: "olefin formation" EXACT [GOC:TermGenie] +synonym: "olefin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900673 ! olefin metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: tt +creation_date: 2012-05-22T04:25:03Z + +[Term] +id: GO:1900675 +name: regulation of F-9775B biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900614 ! F-9775B biosynthetic process +relationship: regulates GO:1900614 ! F-9775B biosynthetic process +created_by: di +creation_date: 2012-05-22T04:26:31Z + +[Term] +id: GO:1900676 +name: negative regulation of F-9775B biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "down regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "downregulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775B biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "inhibition of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900675 ! regulation of F-9775B biosynthetic process +is_a: GO:1900733 ! negative regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900614 ! F-9775B biosynthetic process +relationship: negatively_regulates GO:1900614 ! F-9775B biosynthetic process +created_by: di +creation_date: 2012-05-22T04:26:53Z + +[Term] +id: GO:1900677 +name: positive regulation of F-9775B biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "activation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of F-9775B biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "activation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "up regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-9775B synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775B anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775B biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775B formation" EXACT [GOC:TermGenie] +synonym: "upregulation of F-9775B synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900675 ! regulation of F-9775B biosynthetic process +is_a: GO:1900734 ! positive regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900614 ! F-9775B biosynthetic process +relationship: positively_regulates GO:1900614 ! F-9775B biosynthetic process +created_by: di +creation_date: 2012-05-22T04:27:01Z + +[Term] +id: GO:1900678 +name: regulation of ferricrocin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1905568 ! regulation of ferrichrome biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031171 ! ferricrocin biosynthetic process +relationship: regulates GO:0031171 ! ferricrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:27:53Z + +[Term] +id: GO:1900679 +name: negative regulation of ferricrocin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "downregulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "downregulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ferricrocin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "inhibition of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900678 ! regulation of ferricrocin biosynthetic process +is_a: GO:1905569 ! negative regulation of ferrichrome biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031171 ! ferricrocin biosynthetic process +relationship: negatively_regulates GO:0031171 ! ferricrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:28:15Z + +[Term] +id: GO:1900680 +name: positive regulation of ferricrocin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of ferricrocin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "activation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "activation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "activation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ferricrocin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ferricrocin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ferricrocin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ferricrocin biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "upregulation of ferricrocin biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "upregulation of ferricrocin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ferricrocin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900678 ! regulation of ferricrocin biosynthetic process +is_a: GO:1905570 ! positive regulation of ferrichrome biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031171 ! ferricrocin biosynthetic process +relationship: positively_regulates GO:0031171 ! ferricrocin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:28:23Z + +[Term] +id: GO:1900681 +name: octadecene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving octadecene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "octadecene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-05-22T04:28:28Z + +[Term] +id: GO:1900682 +name: octadecene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of octadecene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "1-octadecene biosynthetic process" EXACT [GOC:mengo_curators] +synonym: "octadecene anabolism" EXACT [GOC:TermGenie] +synonym: "octadecene biosynthesis" EXACT [GOC:TermGenie] +synonym: "octadecene formation" EXACT [GOC:TermGenie] +synonym: "octadecene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900681 ! octadecene metabolic process +created_by: tt +creation_date: 2012-05-22T04:28:49Z + +[Term] +id: GO:1900683 +name: regulation of fumonisin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900541 ! fumonisin biosynthetic process +relationship: regulates GO:1900541 ! fumonisin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:29:38Z + +[Term] +id: GO:1900684 +name: negative regulation of fumonisin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of fumonisin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900683 ! regulation of fumonisin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900541 ! fumonisin biosynthetic process +relationship: negatively_regulates GO:1900541 ! fumonisin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:29:59Z + +[Term] +id: GO:1900685 +name: positive regulation of fumonisin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of fumonisin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "activation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumonisin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of fumonisin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of fumonisin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of fumonisin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of fumonisin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of fumonisin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900683 ! regulation of fumonisin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900541 ! fumonisin biosynthetic process +relationship: positively_regulates GO:1900541 ! fumonisin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:30:06Z + +[Term] +id: GO:1900686 +name: regulation of gerfelin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900578 ! gerfelin biosynthetic process +relationship: regulates GO:1900578 ! gerfelin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:49:44Z + +[Term] +id: GO:1900687 +name: negative regulation of gerfelin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of gerfelin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900686 ! regulation of gerfelin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900578 ! gerfelin biosynthetic process +relationship: negatively_regulates GO:1900578 ! gerfelin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:50:05Z + +[Term] +id: GO:1900688 +name: positive regulation of gerfelin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of gerfelin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "activation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of gerfelin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gerfelin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of gerfelin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gerfelin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of gerfelin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of gerfelin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900686 ! regulation of gerfelin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900578 ! gerfelin biosynthetic process +relationship: positively_regulates GO:1900578 ! gerfelin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:50:12Z + +[Term] +id: GO:1900689 +name: regulation of gliotoxin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001310 ! gliotoxin biosynthetic process +relationship: regulates GO:2001310 ! gliotoxin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:51:38Z + +[Term] +id: GO:1900690 +name: negative regulation of gliotoxin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of gliotoxin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900689 ! regulation of gliotoxin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001310 ! gliotoxin biosynthetic process +relationship: negatively_regulates GO:2001310 ! gliotoxin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:52:00Z + +[Term] +id: GO:1900691 +name: positive regulation of gliotoxin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of gliotoxin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "activation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gliotoxin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of gliotoxin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gliotoxin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of gliotoxin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of gliotoxin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900689 ! regulation of gliotoxin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001310 ! gliotoxin biosynthetic process +relationship: positively_regulates GO:2001310 ! gliotoxin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:52:08Z + +[Term] +id: GO:1900692 +name: regulation of (+)-kotanin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900596 ! (+)-kotanin biosynthetic process +relationship: regulates GO:1900596 ! (+)-kotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:53:04Z + +[Term] +id: GO:1900693 +name: negative regulation of (+)-kotanin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of (+)-kotanin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900692 ! regulation of (+)-kotanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900596 ! (+)-kotanin biosynthetic process +relationship: negatively_regulates GO:1900596 ! (+)-kotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:53:26Z + +[Term] +id: GO:1900694 +name: positive regulation of (+)-kotanin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of (+)-kotanin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "activation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of (+)-kotanin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of (+)-kotanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of (+)-kotanin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of (+)-kotanin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of (+)-kotanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900692 ! regulation of (+)-kotanin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900596 ! (+)-kotanin biosynthetic process +relationship: positively_regulates GO:1900596 ! (+)-kotanin biosynthetic process +created_by: di +creation_date: 2012-05-22T04:53:33Z + +[Term] +id: GO:1900695 +name: regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +relationship: regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +created_by: di +creation_date: 2012-05-22T04:54:24Z + +[Term] +id: GO:1900696 +name: negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "down regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "downregulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of N',N'',N'''-triacetylfusarinine C biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "inhibition of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900695 ! regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +relationship: negatively_regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +created_by: di +creation_date: 2012-05-22T04:54:45Z + +[Term] +id: GO:1900697 +name: positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "activation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of N',N'',N'''-triacetylfusarinine C biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "activation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "up regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of N',N'',N'''-triacetylfusarinine C anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of N',N'',N'''-triacetylfusarinine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of N',N'',N'''-triacetylfusarinine C formation" EXACT [GOC:TermGenie] +synonym: "upregulation of N',N'',N'''-triacetylfusarinine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900695 ! regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +relationship: positively_regulates GO:1900551 ! N',N'',N'''-triacetylfusarinine C biosynthetic process +created_by: di +creation_date: 2012-05-22T04:54:56Z + +[Term] +id: GO:1900698 +name: regulation of o-orsellinic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900584 ! o-orsellinic acid biosynthetic process +relationship: regulates GO:1900584 ! o-orsellinic acid biosynthetic process +created_by: di +creation_date: 2012-05-22T04:56:46Z + +[Term] +id: GO:1900699 +name: negative regulation of o-orsellinic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of o-orsellinic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "inhibition of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900698 ! regulation of o-orsellinic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900584 ! o-orsellinic acid biosynthetic process +relationship: negatively_regulates GO:1900584 ! o-orsellinic acid biosynthetic process +created_by: di +creation_date: 2012-05-22T04:57:08Z + +[Term] +id: GO:1900700 +name: positive regulation of o-orsellinic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "activation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of o-orsellinic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "activation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of o-orsellinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of o-orsellinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of o-orsellinic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of o-orsellinic acid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of o-orsellinic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900698 ! regulation of o-orsellinic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900584 ! o-orsellinic acid biosynthetic process +relationship: positively_regulates GO:1900584 ! o-orsellinic acid biosynthetic process +created_by: di +creation_date: 2012-05-22T04:57:16Z + +[Term] +id: GO:1900701 +name: regulation of orcinol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of orcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "regulation of orcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046197 ! orcinol biosynthetic process +relationship: regulates GO:0046197 ! orcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:57:59Z + +[Term] +id: GO:1900702 +name: negative regulation of orcinol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of orcinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of orcinol formation" EXACT [GOC:TermGenie] +synonym: "inhibition of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of orcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900701 ! regulation of orcinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046197 ! orcinol biosynthetic process +relationship: negatively_regulates GO:0046197 ! orcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:58:20Z + +[Term] +id: GO:1900703 +name: positive regulation of orcinol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "activation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of orcinol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "activation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of orcinol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of orcinol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of orcinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of orcinol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of orcinol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of orcinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900701 ! regulation of orcinol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046197 ! orcinol biosynthetic process +relationship: positively_regulates GO:0046197 ! orcinol biosynthetic process +created_by: di +creation_date: 2012-05-22T04:58:28Z + +[Term] +id: GO:1900704 +name: regulation of siderophore biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of siderophore biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "regulation of siderophore synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019290 ! siderophore biosynthetic process +relationship: regulates GO:0019290 ! siderophore biosynthetic process +created_by: di +creation_date: 2012-05-22T04:59:28Z + +[Term] +id: GO:1900705 +name: negative regulation of siderophore biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "down regulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down-regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "downregulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "downregulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "downregulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of siderophore biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "inhibition of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "inhibition of siderophore formation" EXACT [GOC:TermGenie] +synonym: "inhibition of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of siderophore synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900704 ! regulation of siderophore biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019290 ! siderophore biosynthetic process +relationship: negatively_regulates GO:0019290 ! siderophore biosynthetic process +created_by: di +creation_date: 2012-05-22T04:59:49Z + +[Term] +id: GO:1900706 +name: positive regulation of siderophore biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "activation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of siderophore biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "activation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "activation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "activation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "up regulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up-regulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of siderophore synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of siderochrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of siderochrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of siderophore anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of siderophore biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of siderophore biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of siderophore biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "upregulation of siderophore biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "upregulation of siderophore formation" EXACT [GOC:TermGenie] +synonym: "upregulation of siderophore synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900704 ! regulation of siderophore biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019290 ! siderophore biosynthetic process +relationship: positively_regulates GO:0019290 ! siderophore biosynthetic process +created_by: di +creation_date: 2012-05-22T05:00:00Z + +[Term] +id: GO:1900707 +name: regulation of tensidol A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900605 ! tensidol A biosynthetic process +relationship: regulates GO:1900605 ! tensidol A biosynthetic process +created_by: di +creation_date: 2012-05-22T05:01:44Z + +[Term] +id: GO:1900708 +name: negative regulation of tensidol A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900707 ! regulation of tensidol A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900605 ! tensidol A biosynthetic process +relationship: negatively_regulates GO:1900605 ! tensidol A biosynthetic process +created_by: di +creation_date: 2012-05-22T05:02:04Z + +[Term] +id: GO:1900709 +name: positive regulation of tensidol A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "activation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of tensidol A biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "activation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol A synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol A anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol A biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol A formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900707 ! regulation of tensidol A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900605 ! tensidol A biosynthetic process +relationship: positively_regulates GO:1900605 ! tensidol A biosynthetic process +created_by: di +creation_date: 2012-05-22T05:02:12Z + +[Term] +id: GO:1900710 +name: regulation of tensidol B biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900608 ! tensidol B biosynthetic process +relationship: regulates GO:1900608 ! tensidol B biosynthetic process +created_by: di +creation_date: 2012-05-22T05:02:55Z + +[Term] +id: GO:1900711 +name: negative regulation of tensidol B biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "down regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol B biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "inhibition of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900710 ! regulation of tensidol B biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900608 ! tensidol B biosynthetic process +relationship: negatively_regulates GO:1900608 ! tensidol B biosynthetic process +created_by: di +creation_date: 2012-05-22T05:03:16Z + +[Term] +id: GO:1900712 +name: positive regulation of tensidol B biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "activation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of tensidol B biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "activation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tensidol B synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol B anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol B biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol B formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tensidol B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900710 ! regulation of tensidol B biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900608 ! tensidol B biosynthetic process +relationship: positively_regulates GO:1900608 ! tensidol B biosynthetic process +created_by: di +creation_date: 2012-05-22T05:03:23Z + +[Term] +id: GO:1900713 +name: regulation of violaceol I biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900590 ! violaceol I biosynthetic process +relationship: regulates GO:1900590 ! violaceol I biosynthetic process +created_by: di +creation_date: 2012-05-22T05:04:12Z + +[Term] +id: GO:1900714 +name: negative regulation of violaceol I biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol I biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900713 ! regulation of violaceol I biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900590 ! violaceol I biosynthetic process +relationship: negatively_regulates GO:1900590 ! violaceol I biosynthetic process +created_by: di +creation_date: 2012-05-22T05:04:33Z + +[Term] +id: GO:1900715 +name: positive regulation of violaceol I biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "activation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of violaceol I biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "activation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol I synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol I anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol I biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol I biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol I formation" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol I synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900713 ! regulation of violaceol I biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900590 ! violaceol I biosynthetic process +relationship: positively_regulates GO:1900590 ! violaceol I biosynthetic process +created_by: di +creation_date: 2012-05-22T05:04:41Z + +[Term] +id: GO:1900716 +name: regulation of violaceol II biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900593 ! violaceol II biosynthetic process +relationship: regulates GO:1900593 ! violaceol II biosynthetic process +created_by: di +creation_date: 2012-05-22T05:05:37Z + +[Term] +id: GO:1900717 +name: negative regulation of violaceol II biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "down regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "downregulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol II biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "inhibition of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900716 ! regulation of violaceol II biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900593 ! violaceol II biosynthetic process +relationship: negatively_regulates GO:1900593 ! violaceol II biosynthetic process +created_by: di +creation_date: 2012-05-22T05:05:58Z + +[Term] +id: GO:1900718 +name: positive regulation of violaceol II biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "activation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of violaceol II biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "activation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "up regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of violaceol II synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol II anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol II biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol II biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol II formation" EXACT [GOC:TermGenie] +synonym: "upregulation of violaceol II synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900716 ! regulation of violaceol II biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900593 ! violaceol II biosynthetic process +relationship: positively_regulates GO:1900593 ! violaceol II biosynthetic process +created_by: di +creation_date: 2012-05-22T05:06:06Z + +[Term] +id: GO:1900719 +name: regulation of uterine smooth muscle relaxation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation." [GOC:TermGenie] +synonym: "regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +is_a: GO:1901080 ! regulation of relaxation of smooth muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044558 ! uterine smooth muscle relaxation +relationship: regulates GO:0044558 ! uterine smooth muscle relaxation +created_by: jl +creation_date: 2012-05-24T03:12:26Z + +[Term] +id: GO:1900720 +name: negative regulation of uterine smooth muscle relaxation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation." [GOC:TermGenie] +synonym: "down regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "down regulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "down-regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "down-regulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "downregulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "downregulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "inhibition of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "inhibition of uterine smooth muscle relaxation" NARROW [GOC:TermGenie] +synonym: "negative regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +is_a: GO:1900719 ! regulation of uterine smooth muscle relaxation +is_a: GO:1901081 ! negative regulation of relaxation of smooth muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044558 ! uterine smooth muscle relaxation +relationship: negatively_regulates GO:0044558 ! uterine smooth muscle relaxation +created_by: jl +creation_date: 2012-05-24T03:12:49Z + +[Term] +id: GO:1900721 +name: positive regulation of uterine smooth muscle relaxation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation." [GOC:TermGenie] +synonym: "activation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "activation of uterine smooth muscle relaxation" NARROW [GOC:TermGenie] +synonym: "positive regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "up regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "up regulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "up-regulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle relaxation of the uterus" EXACT [GOC:TermGenie] +synonym: "upregulation of uterine smooth muscle relaxation" EXACT [GOC:TermGenie] +is_a: GO:1900719 ! regulation of uterine smooth muscle relaxation +is_a: GO:1901082 ! positive regulation of relaxation of smooth muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044558 ! uterine smooth muscle relaxation +relationship: positively_regulates GO:0044558 ! uterine smooth muscle relaxation +created_by: jl +creation_date: 2012-05-24T03:12:57Z + +[Term] +id: GO:1900722 +name: regulation of protein adenylylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] +synonym: "regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein AMPylation" EXACT [GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018117 ! protein adenylylation +relationship: regulates GO:0018117 ! protein adenylylation +created_by: jl +creation_date: 2012-05-24T03:15:44Z + +[Term] +id: GO:1900723 +name: negative regulation of protein adenylylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] +synonym: "down regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein adenylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein adenylylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein AMPylation" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1900722 ! regulation of protein adenylylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018117 ! protein adenylylation +relationship: negatively_regulates GO:0018117 ! protein adenylylation +created_by: jl +creation_date: 2012-05-24T03:16:06Z + +[Term] +id: GO:1900724 +name: positive regulation of protein adenylylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] +synonym: "activation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "activation of protein adenylylation" NARROW [GOC:TermGenie] +synonym: "activation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "activation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein AMPylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein adenylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein adenylylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein AMPylation" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1900722 ! regulation of protein adenylylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018117 ! protein adenylylation +relationship: positively_regulates GO:0018117 ! protein adenylylation +created_by: jl +creation_date: 2012-05-24T03:16:13Z + +[Term] +id: GO:1900725 +name: osmoregulated periplasmic glucan metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving osmoregulated periplasmic glucan." [GOC:TermGenie, GOC:yaf] +synonym: "osmoregulated periplasmic glucan metabolism" EXACT [GOC:TermGenie] +is_a: GO:0044042 ! glucan metabolic process +created_by: jl +creation_date: 2012-05-24T03:18:32Z + +[Term] +id: GO:1900726 +name: osmoregulated periplasmic glucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan." [GOC:TermGenie, GOC:yaf] +synonym: "osmoregulated periplasmic glucan breakdown" EXACT [GOC:TermGenie] +synonym: "osmoregulated periplasmic glucan catabolism" EXACT [GOC:TermGenie] +synonym: "osmoregulated periplasmic glucan degradation" EXACT [GOC:TermGenie] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:1900725 ! osmoregulated periplasmic glucan metabolic process +created_by: jl +creation_date: 2012-05-24T03:18:54Z + +[Term] +id: GO:1900727 +name: osmoregulated periplasmic glucan biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan." [GOC:TermGenie, GOC:yaf] +synonym: "osmoregulated periplasmic glucan anabolism" EXACT [GOC:TermGenie] +synonym: "osmoregulated periplasmic glucan biosynthesis" EXACT [GOC:TermGenie] +synonym: "osmoregulated periplasmic glucan formation" EXACT [GOC:TermGenie] +synonym: "osmoregulated periplasmic glucan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009250 ! glucan biosynthetic process +is_a: GO:1900725 ! osmoregulated periplasmic glucan metabolic process +created_by: jl +creation_date: 2012-05-24T03:19:02Z + +[Term] +id: GO:1900728 +name: cardiac neural crest cell delamination involved in outflow tract morphogenesis +namespace: biological_process +def: "Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis." [GOC:hjd, GOC:TermGenie, PMID:18539270] +is_a: GO:0036036 ! cardiac neural crest cell delamination +intersection_of: GO:0036036 ! cardiac neural crest cell delamination +intersection_of: part_of GO:0003151 ! outflow tract morphogenesis +relationship: part_of GO:0003151 ! outflow tract morphogenesis +created_by: bf +creation_date: 2012-05-25T09:50:24Z + +[Term] +id: GO:1900729 +name: regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway." [GOC:sjw, GOC:TermGenie, PMID:17157995] +synonym: "regulation of inhibition of adenylate cyclase activity by opioid receptor" RELATED [PMID:17157995] +synonym: "regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of opioid receptor-mediated adenylate cyclase inhibition" RELATED [] +is_a: GO:2000474 ! regulation of opioid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +relationship: regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +created_by: bf +creation_date: 2012-05-25T03:20:49Z + +[Term] +id: GO:1900730 +name: negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway." [GOC:sjw, GOC:TermGenie, PMID:17157995] +synonym: "down regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of adenylate cyclase-inhibiting opioid receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of opioid receptor-mediated adenylate cyclase inhibition" RELATED [] +synonym: "negative regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway" RELATED [GOC:TermGenie] +is_a: GO:1900729 ! regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway +is_a: GO:2000475 ! negative regulation of opioid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +relationship: negatively_regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +created_by: bf +creation_date: 2012-05-25T03:21:12Z + +[Term] +id: GO:1900731 +name: positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway." [GOC:sjw, GOC:TermGenie, PMID:17157995] +synonym: "activation of adenylate cyclase-inhibiting opioid receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of opioid receptor-mediated adenylate cyclase inhibition" RELATED [] +synonym: "up regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1900729 ! regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway +is_a: GO:2000476 ! positive regulation of opioid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +relationship: positively_regulates GO:0031635 ! adenylate cyclase-inhibiting opioid receptor signaling pathway +created_by: bf +creation_date: 2012-05-25T03:21:19Z + +[Term] +id: GO:1900732 +name: regulation of polyketide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polyketide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "regulation of polyketide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030639 ! polyketide biosynthetic process +relationship: regulates GO:0030639 ! polyketide biosynthetic process +created_by: di +creation_date: 2012-05-26T01:29:40Z + +[Term] +id: GO:1900733 +name: negative regulation of polyketide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of polyketide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of polyketide formation" EXACT [GOC:TermGenie] +synonym: "inhibition of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyketide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030639 ! polyketide biosynthetic process +relationship: negatively_regulates GO:0030639 ! polyketide biosynthetic process +created_by: di +creation_date: 2012-05-26T01:30:02Z + +[Term] +id: GO:1900734 +name: positive regulation of polyketide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "activation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of polyketide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "activation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "up regulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyketide synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of polyketide anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of polyketide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of polyketide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of polyketide formation" EXACT [GOC:TermGenie] +synonym: "upregulation of polyketide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030639 ! polyketide biosynthetic process +relationship: positively_regulates GO:0030639 ! polyketide biosynthetic process +created_by: di +creation_date: 2012-05-26T01:30:10Z + +[Term] +id: GO:1900735 +name: positive regulation of flocculation +namespace: biological_process +alt_id: GO:1900479 +def: "Any process that activates or increases the frequency, rate or extent of flocculation." [GOC:dgf, GOC:TermGenie, PMID:10591965, PMID:15466424, PMID:16568252] +synonym: "activation of flocculation" NARROW [GOC:TermGenie] +synonym: "activation of flocculation via cell wall protein-carbohydrate interaction" NARROW [GOC:TermGenie] +synonym: "positive regulation of flocculation via cell wall protein-carbohydrate interaction" RELATED [] +synonym: "up regulation of flocculation" EXACT [GOC:TermGenie] +synonym: "up regulation of flocculation via cell wall protein-carbohydrate interaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of flocculation" EXACT [GOC:TermGenie] +synonym: "up-regulation of flocculation via cell wall protein-carbohydrate interaction" EXACT [GOC:TermGenie] +synonym: "upregulation of flocculation" EXACT [GOC:TermGenie] +synonym: "upregulation of flocculation via cell wall protein-carbohydrate interaction" EXACT [GOC:TermGenie] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0060256 ! regulation of flocculation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000128 ! flocculation +relationship: positively_regulates GO:0000128 ! flocculation +created_by: dgf +creation_date: 2012-05-27T08:27:38Z + +[Term] +id: GO:1900736 +name: regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [] +synonym: "regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +relationship: regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +created_by: rl +creation_date: 2012-05-28T10:07:27Z + +[Term] +id: GO:1900737 +name: negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "down regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "down regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "down-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "downregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "downregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "downregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "downregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "downregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "inhibition of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "inhibition of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "inhibition of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "inhibition of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "inhibition of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "inhibition of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of phospholipase C-activating G-protein coupled receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "negative regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "negative regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [] +synonym: "negative regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:1900736 ! regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +relationship: negatively_regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +created_by: rl +creation_date: 2012-05-28T10:07:48Z + +[Term] +id: GO:1900738 +name: positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "activation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "activation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "activation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "activation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "activation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "activation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "activation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of phospholipase C-activating G-protein coupled receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "positive regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [] +synonym: "positive regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "up regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "up-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger" RELATED [GOC:TermGenie] +synonym: "upregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "upregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipase C-activating dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of phospholipase C-activating G-protein coupled receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of PLC-activating GPCR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:1900736 ! regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +relationship: positively_regulates GO:0007200 ! phospholipase C-activating G protein-coupled receptor signaling pathway +created_by: rl +creation_date: 2012-05-28T10:07:56Z + +[Term] +id: GO:1900739 +name: regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway." [GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:1901028 ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001844 ! protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +relationship: regulates GO:0001844 ! protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +created_by: pr +creation_date: 2012-05-28T02:28:18Z + +[Term] +id: GO:1900740 +name: positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway." [GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "activation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of protein insertion into mitochondrial membrane during induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of protein insertion into mitochondrial membrane involved in induction of apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of protein insertion into mitochondrion membrane during induction of apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1900739 ! regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +is_a: GO:1901030 ! positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +is_a: GO:1903749 ! positive regulation of establishment of protein localization to mitochondrion +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001844 ! protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +relationship: positively_regulates GO:0001844 ! protein insertion into mitochondrial membrane involved in apoptotic signaling pathway +created_by: pr +creation_date: 2012-05-28T02:28:40Z + +[Term] +id: GO:1900741 +name: regulation of filamentous growth of a population of unicellular organisms in response to pH +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH." [GOC:di, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +relationship: regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +created_by: di +creation_date: 2012-05-28T02:34:39Z + +[Term] +id: GO:1900742 +name: negative regulation of filamentous growth of a population of unicellular organisms in response to pH +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH." [GOC:di, GOC:TermGenie] +synonym: "down regulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +synonym: "down-regulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +synonym: "downregulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +synonym: "inhibition of filamentous growth of a population of unicellular organisms in response to pH" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1900429 ! negative regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900741 ! regulation of filamentous growth of a population of unicellular organisms in response to pH +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +relationship: negatively_regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +created_by: di +creation_date: 2012-05-28T02:35:03Z + +[Term] +id: GO:1900743 +name: positive regulation of filamentous growth of a population of unicellular organisms in response to pH +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH." [GOC:di, GOC:TermGenie] +synonym: "activation of filamentous growth of a population of unicellular organisms in response to pH" NARROW [GOC:TermGenie] +synonym: "up regulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +synonym: "up-regulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +synonym: "upregulation of filamentous growth of a population of unicellular organisms in response to pH" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1900430 ! positive regulation of filamentous growth of a population of unicellular organisms +is_a: GO:1900741 ! regulation of filamentous growth of a population of unicellular organisms in response to pH +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +relationship: positively_regulates GO:0036177 ! filamentous growth of a population of unicellular organisms in response to pH +created_by: di +creation_date: 2012-05-28T02:35:11Z + +[Term] +id: GO:1900744 +name: regulation of p38MAPK cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of p38MAPK cascade." [GOC:TermGenie] +synonym: "regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +is_a: GO:0032872 ! regulation of stress-activated MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038066 ! p38MAPK cascade +relationship: regulates GO:0038066 ! p38MAPK cascade +created_by: pm +creation_date: 2012-05-28T02:40:14Z + +[Term] +id: GO:1900745 +name: positive regulation of p38MAPK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of p38MAPK cascade." [GOC:TermGenie] +synonym: "activation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "activation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "activation of p38MAPK cascade" NARROW [GOC:TermGenie] +synonym: "positive regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "positive regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of p38MAPK cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of p38MAPK cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of p38MAPK cascade" EXACT [GOC:TermGenie] +is_a: GO:0032874 ! positive regulation of stress-activated MAPK cascade +is_a: GO:1900744 ! regulation of p38MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038066 ! p38MAPK cascade +relationship: positively_regulates GO:0038066 ! p38MAPK cascade +created_by: pm +creation_date: 2012-05-28T02:40:48Z + +[Term] +id: GO:1900746 +name: regulation of vascular endothelial growth factor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway." [GOC:TermGenie] +synonym: "regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1902547 ! regulation of cellular response to vascular endothelial growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +relationship: regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +created_by: pm +creation_date: 2012-05-29T08:28:06Z + +[Term] +id: GO:1900747 +name: negative regulation of vascular endothelial growth factor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway." [GOC:TermGenie] +synonym: "down regulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular endothelial growth factor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "inhibition of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900746 ! regulation of vascular endothelial growth factor signaling pathway +is_a: GO:1902548 ! negative regulation of cellular response to vascular endothelial growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +relationship: negatively_regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +created_by: pm +creation_date: 2012-05-29T08:28:29Z + +[Term] +id: GO:1900748 +name: positive regulation of vascular endothelial growth factor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway." [GOC:TermGenie] +synonym: "activation of vascular endothelial growth factor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "activation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "activation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular endothelial growth factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular endothelial growth factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of VEGF signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of VEGF-activated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900746 ! regulation of vascular endothelial growth factor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +relationship: positively_regulates GO:0038084 ! vascular endothelial growth factor signaling pathway +created_by: pm +creation_date: 2012-05-29T08:28:36Z + +[Term] +id: GO:1900749 +name: (R)-carnitine transport +namespace: biological_process +def: "The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:16365044, PMID:20357772, PMID:20829798] +synonym: "(-)-Carnitine transport" RELATED [GOC:TermGenie] +synonym: "(-)-L-Carnitine transport" RELATED [GOC:TermGenie] +synonym: "(3R)-3-hydroxy-4-(trimethylammonio)butanoate transport" EXACT [GOC:TermGenie] +synonym: "(R)-Carnitine transport" EXACT [GOC:TermGenie] +synonym: "C7H15NO3 transport" RELATED [GOC:TermGenie] +synonym: "Carnicor transport" RELATED [GOC:TermGenie] +synonym: "Carnitene transport" RELATED [GOC:TermGenie] +synonym: "Carnitine transport" RELATED [GOC:TermGenie] +synonym: "Carnitor transport" RELATED [GOC:TermGenie] +synonym: "L-Carnitine transport" EXACT [GOC:TermGenie] +synonym: "Levocarnitine transport" RELATED [GOC:TermGenie] +synonym: "Vitamin BT transport" RELATED [GOC:TermGenie] +is_a: GO:0015879 ! carnitine transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +created_by: jl +creation_date: 2012-05-29T02:01:17Z + +[Term] +id: GO:1900750 +name: oligopeptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an oligopeptide." [GOC:TermGenie, PMID:21854595] +synonym: "Oligopeptid binding" RELATED [GOC:TermGenie] +synonym: "oligopeptides binding" EXACT [GOC:TermGenie] +synonym: "oligopeptido binding" RELATED [GOC:TermGenie] +is_a: GO:0042277 ! peptide binding +created_by: jl +creation_date: 2012-05-29T02:13:31Z + +[Term] +id: GO:1900751 +name: 4-(trimethylammonio)butanoate transport +namespace: biological_process +def: "The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:16365044, PMID:20357772, PMID:20829798] +synonym: "4-(N-trimethylamino)butyrate transport" EXACT [GOC:TermGenie] +synonym: "4-butyrobetaine transport" EXACT [GOC:TermGenie] +synonym: "Actinine transport" RELATED [GOC:TermGenie] +synonym: "butyrobetaine transport" RELATED [GOC:TermGenie] +synonym: "C7H15NO2 transport" RELATED [GOC:TermGenie] +synonym: "deoxycarnitine transport" RELATED [GOC:TermGenie] +synonym: "gamma-Butyrobetain transport" EXACT [GOC:TermGenie] +synonym: "gamma-butyrobetaine transport" EXACT [GOC:TermGenie] +is_a: GO:0015838 ! amino-acid betaine transport +created_by: jl +creation_date: 2012-05-29T02:32:37Z + +[Term] +id: GO:1900752 +name: malonic acid transport +namespace: biological_process +def: "The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:9128730, PMID:9573154] +synonym: "C3H4O4 transport" RELATED [GOC:TermGenie] +synonym: "H2malo transport" RELATED [GOC:TermGenie] +synonym: "HOOC-CH2-COOH transport" RELATED [GOC:TermGenie] +synonym: "propanedioic acid transport" EXACT [GOC:TermGenie] +is_a: GO:0006835 ! dicarboxylic acid transport +created_by: jl +creation_date: 2012-05-29T02:40:33Z + +[Term] +id: GO:1900753 +name: doxorubicin transport +namespace: biological_process +def: "The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:12057006, PMID:15090538, PMID:19063901, PMID:19651502, PMID:9651400] +synonym: "(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport" EXACT [GOC:TermGenie] +synonym: "(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport" RELATED [GOC:TermGenie] +synonym: "(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione transport" RELATED [GOC:TermGenie] +synonym: "14-hydroxydaunomycin transport" RELATED [GOC:TermGenie] +synonym: "14-hydroxydaunorubicine transport" RELATED [GOC:TermGenie] +synonym: "Adriamycin transport" RELATED [GOC:TermGenie] +synonym: "doxorubicine transport" RELATED [GOC:TermGenie] +synonym: "doxorubicinum transport" RELATED [GOC:TermGenie] +is_a: GO:0015695 ! organic cation transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1901656 ! glycoside transport +created_by: jl +creation_date: 2012-05-29T02:50:43Z + +[Term] +id: GO:1900754 +name: 4-hydroxyphenylacetate transport +namespace: biological_process +def: "The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:9315705] +synonym: "(4-hydroxyphenyl)acetate transport" EXACT [GOC:TermGenie] +synonym: "(p-hydroxyphenyl)acetate transport" EXACT [GOC:TermGenie] +synonym: "2-(4-hydroxyphenyl)ethanoate transport" EXACT [GOC:TermGenie] +synonym: "4-hydroxybenzeneacetate transport" EXACT [GOC:TermGenie] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +created_by: jl +creation_date: 2012-05-29T02:59:02Z + +[Term] +id: GO:1900756 +name: protein processing in phagocytic vesicle +namespace: biological_process +def: "Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation." [GOC:rjd, GOC:TermGenie] +synonym: "peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "protein processing in phagosome" EXACT [GOC:TermGenie] +is_a: GO:0016485 ! protein processing +intersection_of: GO:0016485 ! protein processing +intersection_of: occurs_in GO:0045335 ! phagocytic vesicle +relationship: occurs_in GO:0045335 ! phagocytic vesicle +created_by: rjd +creation_date: 2012-05-29T09:55:14Z + +[Term] +id: GO:1900757 +name: regulation of D-amino-acid oxidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity." [GOC:TermGenie] +synonym: "regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of new yellow enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003884 ! D-amino-acid oxidase activity +relationship: regulates GO:0003884 ! D-amino-acid oxidase activity +created_by: pm +creation_date: 2012-05-31T11:23:45Z + +[Term] +id: GO:1900758 +name: negative regulation of D-amino-acid oxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity." [GOC:TermGenie] +synonym: "down regulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "down regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "down-regulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "downregulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "downregulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "inhibition of D-amino-acid oxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "inhibition of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "negative regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of new yellow enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1900757 ! regulation of D-amino-acid oxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003884 ! D-amino-acid oxidase activity +relationship: negatively_regulates GO:0003884 ! D-amino-acid oxidase activity +created_by: pm +creation_date: 2012-05-31T11:24:06Z + +[Term] +id: GO:1900759 +name: positive regulation of D-amino-acid oxidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity." [GOC:TermGenie] +synonym: "activation of D-amino-acid oxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "activation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "activation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "up regulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "up regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of new yellow enzyme" RELATED [GOC:TermGenie] +synonym: "upregulation of D-amino-acid oxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [GOC:TermGenie] +synonym: "upregulation of L-amino acid:O2 oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of new yellow enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1900757 ! regulation of D-amino-acid oxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003884 ! D-amino-acid oxidase activity +relationship: positively_regulates GO:0003884 ! D-amino-acid oxidase activity +created_by: pm +creation_date: 2012-05-31T11:24:14Z + +[Term] +id: GO:1900760 +name: negative regulation of sterigmatocystin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of sterigmatocystin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of sterigmatocystin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of sterigmatocystin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of sterigmatocystin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of sterigmatocystin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterigmatocystin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterigmatocystin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterigmatocystin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterigmatocystin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterigmatocystin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sterigmatocystin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of sterigmatocystin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sterigmatocystin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of sterigmatocystin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of sterigmatocystin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sterigmatocystin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of sterigmatocystin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sterigmatocystin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of sterigmatocystin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of sterigmatocystin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of sterigmatocystin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of sterigmatocystin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of sterigmatocystin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of sterigmatocystin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010913 ! regulation of sterigmatocystin biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045461 ! sterigmatocystin biosynthetic process +relationship: negatively_regulates GO:0045461 ! sterigmatocystin biosynthetic process +created_by: di +creation_date: 2012-06-04T08:38:30Z + +[Term] +id: GO:1900761 +name: averantin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving averantin." [GOC:di, GOC:TermGenie] +synonym: "averantin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: di +creation_date: 2012-06-04T09:14:22Z + +[Term] +id: GO:1900762 +name: averantin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of averantin." [GOC:di, GOC:TermGenie] +synonym: "averantin breakdown" EXACT [GOC:TermGenie] +synonym: "averantin catabolism" EXACT [GOC:TermGenie] +synonym: "averantin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:1900761 ! averantin metabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: di +creation_date: 2012-06-04T09:14:45Z + +[Term] +id: GO:1900763 +name: averantin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of averantin." [GOC:di, GOC:TermGenie] +synonym: "averantin anabolism" EXACT [GOC:TermGenie] +synonym: "averantin biosynthesis" EXACT [GOC:TermGenie] +synonym: "averantin formation" EXACT [GOC:TermGenie] +synonym: "averantin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900761 ! averantin metabolic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: di +creation_date: 2012-06-04T09:14:52Z + +[Term] +id: GO:1900764 +name: emericellin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving emericellin." [GOC:di, GOC:TermGenie] +synonym: "emericellin metabolism" EXACT [GOC:TermGenie] +synonym: "Variecoxanthone B metabolic process" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B metabolism" RELATED [GOC:TermGenie] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:2001305 ! xanthone-containing compound metabolic process +created_by: di +creation_date: 2012-06-04T09:17:58Z + +[Term] +id: GO:1900765 +name: emericellin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of emericellin." [GOC:di, GOC:TermGenie] +synonym: "emericellin breakdown" EXACT [GOC:TermGenie] +synonym: "emericellin catabolism" EXACT [GOC:TermGenie] +synonym: "emericellin degradation" EXACT [GOC:TermGenie] +synonym: "Variecoxanthone B breakdown" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B catabolic process" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B catabolism" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B degradation" RELATED [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900764 ! emericellin metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-06-04T09:18:22Z + +[Term] +id: GO:1900766 +name: emericellin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of emericellin." [GOC:di, GOC:TermGenie] +synonym: "emericellin anabolism" EXACT [GOC:TermGenie] +synonym: "emericellin biosynthesis" EXACT [GOC:TermGenie] +synonym: "emericellin formation" EXACT [GOC:TermGenie] +synonym: "emericellin synthesis" EXACT [GOC:TermGenie] +synonym: "Variecoxanthone B anabolism" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B biosynthesis" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B formation" RELATED [GOC:TermGenie] +synonym: "Variecoxanthone B synthesis" RELATED [GOC:TermGenie] +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900764 ! emericellin metabolic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:2001307 ! xanthone-containing compound biosynthetic process +created_by: di +creation_date: 2012-06-04T09:18:29Z + +[Term] +id: GO:1900767 +name: fonsecin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fonsecin." [GOC:di, GOC:TermGenie] +synonym: "fonsecin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:1900785 ! naphtho-gamma-pyrone metabolic process +created_by: di +creation_date: 2012-06-04T09:21:14Z + +[Term] +id: GO:1900768 +name: fonsecin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fonsecin." [GOC:di, GOC:TermGenie] +synonym: "fonsecin breakdown" EXACT [GOC:TermGenie] +synonym: "fonsecin catabolism" EXACT [GOC:TermGenie] +synonym: "fonsecin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1900767 ! fonsecin metabolic process +is_a: GO:1900786 ! naphtho-gamma-pyrone catabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-06-04T09:21:38Z + +[Term] +id: GO:1900769 +name: fonsecin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fonsecin." [GOC:di, GOC:TermGenie] +synonym: "fonsecin anabolism" EXACT [GOC:TermGenie] +synonym: "fonsecin biosynthesis" EXACT [GOC:TermGenie] +synonym: "fonsecin formation" EXACT [GOC:TermGenie] +synonym: "fonsecin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900767 ! fonsecin metabolic process +is_a: GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-06-04T09:21:49Z + +[Term] +id: GO:1900770 +name: fumitremorgin B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumitremorgin B." [GOC:di, GOC:TermGenie] +synonym: "fumitremorgin B metabolism" EXACT [GOC:TermGenie] +synonym: "Lanosulin metabolic process" RELATED [GOC:TermGenie] +synonym: "Lanosulin metabolism" RELATED [GOC:TermGenie] +is_a: GO:0035834 ! indole alkaloid metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: di +creation_date: 2012-06-04T09:25:18Z + +[Term] +id: GO:1900771 +name: fumitremorgin B catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumitremorgin B." [GOC:di, GOC:TermGenie] +synonym: "fumitremorgin B breakdown" EXACT [GOC:TermGenie] +synonym: "fumitremorgin B catabolism" EXACT [GOC:TermGenie] +synonym: "fumitremorgin B degradation" EXACT [GOC:TermGenie] +synonym: "Lanosulin breakdown" RELATED [GOC:TermGenie] +synonym: "Lanosulin catabolic process" RELATED [GOC:TermGenie] +synonym: "Lanosulin catabolism" RELATED [GOC:TermGenie] +synonym: "Lanosulin degradation" RELATED [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900770 ! fumitremorgin B metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +created_by: di +creation_date: 2012-06-04T09:25:43Z + +[Term] +id: GO:1900772 +name: fumitremorgin B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumitremorgin B." [GOC:di, GOC:TermGenie] +synonym: "fumitremorgin B anabolism" EXACT [GOC:TermGenie] +synonym: "fumitremorgin B biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumitremorgin B formation" EXACT [GOC:TermGenie] +synonym: "fumitremorgin B synthesis" EXACT [GOC:TermGenie] +synonym: "Lanosulin anabolism" RELATED [GOC:TermGenie] +synonym: "Lanosulin biosynthesis" RELATED [GOC:TermGenie] +synonym: "Lanosulin biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Lanosulin formation" RELATED [GOC:TermGenie] +synonym: "Lanosulin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:1900770 ! fumitremorgin B metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +created_by: di +creation_date: 2012-06-04T09:25:50Z + +[Term] +id: GO:1900773 +name: fumiquinazoline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumiquinazoline." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline metabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazolines metabolic process" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines metabolism" RELATED [GOC:TermGenie] +is_a: GO:0035834 ! indole alkaloid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-06-04T09:29:22Z + +[Term] +id: GO:1900774 +name: fumiquinazoline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumiquinazoline." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline breakdown" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline catabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline degradation" EXACT [GOC:TermGenie] +synonym: "fumiquinazolines breakdown" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines catabolic process" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines catabolism" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines degradation" RELATED [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900773 ! fumiquinazoline metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-06-04T09:29:46Z + +[Term] +id: GO:1900775 +name: fumiquinazoline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumiquinazoline." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline anabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline formation" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline synthesis" EXACT [GOC:TermGenie] +synonym: "fumiquinazolines anabolism" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines biosynthesis" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines biosynthetic process" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines formation" RELATED [GOC:TermGenie] +synonym: "fumiquinazolines synthesis" RELATED [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:1900773 ! fumiquinazoline metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-06-04T09:29:54Z + +[Term] +id: GO:1900776 +name: fumiquinazoline A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumiquinazoline A." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline A metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900773 ! fumiquinazoline metabolic process +created_by: di +creation_date: 2012-06-04T09:29:58Z + +[Term] +id: GO:1900777 +name: fumiquinazoline A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline A breakdown" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline A catabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline A degradation" EXACT [GOC:TermGenie] +is_a: GO:1900774 ! fumiquinazoline catabolic process +is_a: GO:1900776 ! fumiquinazoline A metabolic process +created_by: di +creation_date: 2012-06-04T09:30:18Z + +[Term] +id: GO:1900778 +name: fumiquinazoline A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumiquinazoline A." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline A anabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline A biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline A formation" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline A synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900775 ! fumiquinazoline biosynthetic process +is_a: GO:1900776 ! fumiquinazoline A metabolic process +created_by: di +creation_date: 2012-06-04T09:30:25Z + +[Term] +id: GO:1900779 +name: fumiquinazoline C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumiquinazoline C." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline C metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900773 ! fumiquinazoline metabolic process +created_by: di +creation_date: 2012-06-04T09:30:30Z + +[Term] +id: GO:1900780 +name: fumiquinazoline C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline C breakdown" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline C catabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline C degradation" EXACT [GOC:TermGenie] +is_a: GO:1900774 ! fumiquinazoline catabolic process +is_a: GO:1900779 ! fumiquinazoline C metabolic process +created_by: di +creation_date: 2012-06-04T09:30:51Z + +[Term] +id: GO:1900781 +name: fumiquinazoline C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumiquinazoline C." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline C anabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline C biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline C formation" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline C synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900775 ! fumiquinazoline biosynthetic process +is_a: GO:1900779 ! fumiquinazoline C metabolic process +created_by: di +creation_date: 2012-06-04T09:30:58Z + +[Term] +id: GO:1900782 +name: fumiquinazoline F metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumiquinazoline F." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline F metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042430 ! indole-containing compound metabolic process +is_a: GO:1900773 ! fumiquinazoline metabolic process +created_by: di +creation_date: 2012-06-04T09:31:06Z + +[Term] +id: GO:1900783 +name: fumiquinazoline F catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline F breakdown" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline F catabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline F degradation" EXACT [GOC:TermGenie] +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:1900774 ! fumiquinazoline catabolic process +is_a: GO:1900782 ! fumiquinazoline F metabolic process +created_by: di +creation_date: 2012-06-04T09:31:27Z + +[Term] +id: GO:1900784 +name: fumiquinazoline F biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumiquinazoline F." [GOC:di, GOC:TermGenie] +synonym: "fumiquinazoline F anabolism" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline F biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline F formation" EXACT [GOC:TermGenie] +synonym: "fumiquinazoline F synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:1900775 ! fumiquinazoline biosynthetic process +is_a: GO:1900782 ! fumiquinazoline F metabolic process +created_by: di +creation_date: 2012-06-04T09:31:34Z + +[Term] +id: GO:1900785 +name: naphtho-gamma-pyrone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving naphtho-gamma-pyrone." [GOC:di, GOC:TermGenie] +synonym: "naphtho-gamma-pyrone metabolism" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones metabolic process" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones metabolism" RELATED [GOC:TermGenie] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-06-04T09:35:32Z + +[Term] +id: GO:1900786 +name: naphtho-gamma-pyrone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone." [GOC:di, GOC:TermGenie] +synonym: "naphtho-gamma-pyrone breakdown" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrone catabolism" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrone degradation" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones breakdown" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones catabolic process" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones catabolism" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones degradation" RELATED [GOC:TermGenie] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900785 ! naphtho-gamma-pyrone metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-06-04T09:35:54Z + +[Term] +id: GO:1900787 +name: naphtho-gamma-pyrone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone." [GOC:di, GOC:TermGenie] +synonym: "naphtho-gamma-pyrone anabolism" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrone biosynthesis" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrone formation" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrone synthesis" EXACT [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones anabolism" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones biosynthesis" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones biosynthetic process" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones formation" RELATED [GOC:TermGenie] +synonym: "naphtho-gamma-pyrones synthesis" RELATED [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1900785 ! naphtho-gamma-pyrone metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-06-04T09:36:02Z + +[Term] +id: GO:1900788 +name: pseurotin A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pseurotin A." [GOC:di, GOC:TermGenie] +synonym: "pseurotin A metabolism" EXACT [GOC:TermGenie] +synonym: "Pseurotin metabolic process" RELATED [GOC:TermGenie] +synonym: "Pseurotin metabolism" RELATED [GOC:TermGenie] +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: di +creation_date: 2012-06-04T09:37:18Z + +[Term] +id: GO:1900789 +name: pseurotin A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pseurotin A." [GOC:di, GOC:TermGenie] +synonym: "pseurotin A breakdown" EXACT [GOC:TermGenie] +synonym: "pseurotin A catabolism" EXACT [GOC:TermGenie] +synonym: "pseurotin A degradation" EXACT [GOC:TermGenie] +synonym: "Pseurotin breakdown" RELATED [GOC:TermGenie] +synonym: "Pseurotin catabolic process" RELATED [GOC:TermGenie] +synonym: "Pseurotin catabolism" RELATED [GOC:TermGenie] +synonym: "Pseurotin degradation" RELATED [GOC:TermGenie] +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900788 ! pseurotin A metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: di +creation_date: 2012-06-04T09:37:41Z + +[Term] +id: GO:1900790 +name: pseurotin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pseurotin A." [GOC:di, GOC:TermGenie] +synonym: "pseurotin A anabolism" EXACT [GOC:TermGenie] +synonym: "pseurotin A biosynthesis" EXACT [GOC:TermGenie] +synonym: "pseurotin A formation" EXACT [GOC:TermGenie] +synonym: "pseurotin A synthesis" EXACT [GOC:TermGenie] +synonym: "Pseurotin anabolism" RELATED [GOC:TermGenie] +synonym: "Pseurotin biosynthesis" RELATED [GOC:TermGenie] +synonym: "Pseurotin biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Pseurotin formation" RELATED [GOC:TermGenie] +synonym: "Pseurotin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1900788 ! pseurotin A metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: di +creation_date: 2012-06-04T09:37:49Z + +[Term] +id: GO:1900791 +name: shamixanthone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving shamixanthone." [GOC:di, GOC:TermGenie] +synonym: "shamixanthone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: di +creation_date: 2012-06-04T09:40:20Z + +[Term] +id: GO:1900792 +name: shamixanthone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of shamixanthone." [GOC:di, GOC:TermGenie] +synonym: "shamixanthone breakdown" EXACT [GOC:TermGenie] +synonym: "shamixanthone catabolism" EXACT [GOC:TermGenie] +synonym: "shamixanthone degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900791 ! shamixanthone metabolic process +created_by: di +creation_date: 2012-06-04T09:40:42Z + +[Term] +id: GO:1900793 +name: shamixanthone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of shamixanthone." [GOC:di, GOC:TermGenie] +synonym: "shamixanthone anabolism" EXACT [GOC:TermGenie] +synonym: "shamixanthone biosynthesis" EXACT [GOC:TermGenie] +synonym: "shamixanthone formation" EXACT [GOC:TermGenie] +synonym: "shamixanthone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900791 ! shamixanthone metabolic process +created_by: di +creation_date: 2012-06-04T09:40:49Z + +[Term] +id: GO:1900794 +name: terrequinone A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving terrequinone A." [GOC:di, GOC:TermGenie] +synonym: "terrequinone A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: di +creation_date: 2012-06-04T09:45:20Z + +[Term] +id: GO:1900795 +name: terrequinone A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of terrequinone A." [GOC:di, GOC:TermGenie] +synonym: "terrequinone A breakdown" EXACT [GOC:TermGenie] +synonym: "terrequinone A catabolism" EXACT [GOC:TermGenie] +synonym: "terrequinone A degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900794 ! terrequinone A metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: di +creation_date: 2012-06-04T09:45:41Z + +[Term] +id: GO:1900796 +name: terrequinone A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of terrequinone A." [GOC:di, GOC:TermGenie] +synonym: "terrequinone A anabolism" EXACT [GOC:TermGenie] +synonym: "terrequinone A biosynthesis" EXACT [GOC:TermGenie] +synonym: "terrequinone A formation" EXACT [GOC:TermGenie] +synonym: "terrequinone A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900794 ! terrequinone A metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: di +creation_date: 2012-06-04T09:45:48Z + +[Term] +id: GO:1900797 +name: cordyol C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cordyol C." [GOC:di, GOC:TermGenie] +synonym: "cordyol C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0019748 ! secondary metabolic process +created_by: di +creation_date: 2012-06-04T09:47:48Z + +[Term] +id: GO:1900798 +name: cordyol C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cordyol C." [GOC:di, GOC:TermGenie] +synonym: "cordyol C breakdown" EXACT [GOC:TermGenie] +synonym: "cordyol C catabolism" EXACT [GOC:TermGenie] +synonym: "cordyol C degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900797 ! cordyol C metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: di +creation_date: 2012-06-04T09:48:10Z + +[Term] +id: GO:1900799 +name: cordyol C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cordyol C." [GOC:di, GOC:TermGenie] +synonym: "cordyol C anabolism" EXACT [GOC:TermGenie] +synonym: "cordyol C biosynthesis" EXACT [GOC:TermGenie] +synonym: "cordyol C formation" EXACT [GOC:TermGenie] +synonym: "cordyol C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900797 ! cordyol C metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: di +creation_date: 2012-06-04T09:48:17Z + +[Term] +id: GO:1900800 +name: cspyrone B1 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cspyrone B1." [GOC:di, GOC:TermGenie] +synonym: "cspyrone B1 metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901334 ! lactone metabolic process +created_by: di +creation_date: 2012-06-04T09:50:37Z + +[Term] +id: GO:1900801 +name: cspyrone B1 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cspyrone B1." [GOC:di, GOC:TermGenie] +synonym: "cspyrone B1 breakdown" EXACT [GOC:TermGenie] +synonym: "cspyrone B1 catabolism" EXACT [GOC:TermGenie] +synonym: "cspyrone B1 degradation" EXACT [GOC:TermGenie] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900800 ! cspyrone B1 metabolic process +is_a: GO:1901335 ! lactone catabolic process +created_by: di +creation_date: 2012-06-04T09:50:58Z + +[Term] +id: GO:1900802 +name: cspyrone B1 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cspyrone B1." [GOC:di, GOC:TermGenie] +synonym: "cspyrone B1 anabolism" EXACT [GOC:TermGenie] +synonym: "cspyrone B1 biosynthesis" EXACT [GOC:TermGenie] +synonym: "cspyrone B1 formation" EXACT [GOC:TermGenie] +synonym: "cspyrone B1 synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900800 ! cspyrone B1 metabolic process +is_a: GO:1901336 ! lactone biosynthetic process +created_by: di +creation_date: 2012-06-04T09:51:06Z + +[Term] +id: GO:1900803 +name: brevianamide F metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving brevianamide F." [GOC:di, GOC:TermGenie] +synonym: "brevianamide F metabolism" EXACT [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) metabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro metabolic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro metabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline metabolic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline metabolism" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride metabolic process" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride metabolism" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride metabolic process" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride metabolism" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine metabolic process" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine metabolism" RELATED [GOC:TermGenie] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0042430 ! indole-containing compound metabolic process +created_by: di +creation_date: 2012-06-04T09:52:19Z + +[Term] +id: GO:1900804 +name: brevianamide F catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of brevianamide F." [GOC:di, GOC:TermGenie] +synonym: "brevianamide F breakdown" EXACT [GOC:TermGenie] +synonym: "brevianamide F catabolism" EXACT [GOC:TermGenie] +synonym: "brevianamide F degradation" EXACT [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) breakdown" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) catabolic process" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) catabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) degradation" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro breakdown" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro catabolic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro catabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro degradation" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline breakdown" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline catabolic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline catabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline degradation" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride breakdown" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride catabolic process" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride catabolism" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride degradation" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride breakdown" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride catabolic process" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride catabolism" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride degradation" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine breakdown" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine catabolic process" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine catabolism" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine degradation" RELATED [GOC:TermGenie] +is_a: GO:0042436 ! indole-containing compound catabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900803 ! brevianamide F metabolic process +created_by: di +creation_date: 2012-06-04T09:52:41Z + +[Term] +id: GO:1900805 +name: brevianamide F biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of brevianamide F." [GOC:di, GOC:TermGenie] +synonym: "brevianamide F anabolism" EXACT [GOC:TermGenie] +synonym: "brevianamide F biosynthesis" EXACT [GOC:TermGenie] +synonym: "brevianamide F formation" EXACT [GOC:TermGenie] +synonym: "brevianamide F synthesis" EXACT [GOC:TermGenie] +synonym: "C16H17N3O2 anabolism" RELATED [GOC:TermGenie] +synonym: "C16H17N3O2 biosynthesis" RELATED [GOC:TermGenie] +synonym: "C16H17N3O2 biosynthetic process" RELATED [GOC:TermGenie] +synonym: "C16H17N3O2 formation" RELATED [GOC:TermGenie] +synonym: "C16H17N3O2 synthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) anabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) biosynthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) biosynthetic process" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) formation" RELATED [GOC:TermGenie] +synonym: "cyclo-(Trp-Pro) synthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro anabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro biosynthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro biosynthetic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro formation" RELATED [GOC:TermGenie] +synonym: "cyclo-L-Trp-L-Pro synthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline anabolism" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline biosynthesis" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline biosynthetic process" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline formation" RELATED [GOC:TermGenie] +synonym: "cyclo-L-tryptophanyl-L-proline synthesis" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride anabolism" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride biosynthesis" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride biosynthetic process" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride formation" RELATED [GOC:TermGenie] +synonym: "L-prolyl-L-tryptophan anhydride synthesis" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride anabolism" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride biosynthesis" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride biosynthetic process" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride formation" RELATED [GOC:TermGenie] +synonym: "L-tryptophyl-L-proline cyclic anhydride synthesis" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine anabolism" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine formation" RELATED [GOC:TermGenie] +synonym: "tryptophan-proline diketopiperazine synthesis" RELATED [GOC:TermGenie] +is_a: GO:0042435 ! indole-containing compound biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900803 ! brevianamide F metabolic process +created_by: di +creation_date: 2012-06-04T09:52:48Z + +[Term] +id: GO:1900806 +name: ergot alkaloid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ergot alkaloid." [GOC:di, GOC:TermGenie] +synonym: "ergot alkaloid breakdown" EXACT [GOC:TermGenie] +synonym: "ergot alkaloid catabolism" EXACT [GOC:TermGenie] +synonym: "ergot alkaloid degradation" EXACT [GOC:TermGenie] +synonym: "ergot alkaloids breakdown" RELATED [GOC:TermGenie] +synonym: "ergot alkaloids catabolic process" RELATED [GOC:TermGenie] +synonym: "ergot alkaloids catabolism" RELATED [GOC:TermGenie] +synonym: "ergot alkaloids degradation" RELATED [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0035836 ! ergot alkaloid metabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +created_by: di +creation_date: 2012-06-04T09:57:39Z + +[Term] +id: GO:1900807 +name: fumigaclavine C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumigaclavine C." [GOC:di, GOC:TermGenie] +synonym: "fumigaclavine C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035836 ! ergot alkaloid metabolic process +is_a: GO:1900619 ! acetate ester metabolic process +created_by: di +creation_date: 2012-06-04T09:59:32Z + +[Term] +id: GO:1900808 +name: fumigaclavine C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumigaclavine C." [GOC:di, GOC:TermGenie] +synonym: "fumigaclavine C breakdown" EXACT [GOC:TermGenie] +synonym: "fumigaclavine C catabolism" EXACT [GOC:TermGenie] +synonym: "fumigaclavine C degradation" EXACT [GOC:TermGenie] +is_a: GO:1900806 ! ergot alkaloid catabolic process +is_a: GO:1900807 ! fumigaclavine C metabolic process +created_by: di +creation_date: 2012-06-04T09:59:55Z + +[Term] +id: GO:1900809 +name: fumigaclavine C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumigaclavine C." [GOC:di, GOC:TermGenie] +synonym: "fumigaclavine C anabolism" EXACT [GOC:TermGenie] +synonym: "fumigaclavine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumigaclavine C formation" EXACT [GOC:TermGenie] +synonym: "fumigaclavine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0035837 ! ergot alkaloid biosynthetic process +is_a: GO:1900620 ! acetate ester biosynthetic process +is_a: GO:1900807 ! fumigaclavine C metabolic process +created_by: di +creation_date: 2012-06-04T10:00:06Z + +[Term] +id: GO:1900810 +name: helvolic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving helvolic acid." [GOC:di, GOC:TermGenie] +synonym: "Fumigacin metabolic process" RELATED [GOC:TermGenie] +synonym: "Fumigacin metabolism" RELATED [GOC:TermGenie] +synonym: "helvolic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +created_by: di +creation_date: 2012-06-04T10:02:28Z + +[Term] +id: GO:1900811 +name: helvolic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of helvolic acid." [GOC:di, GOC:TermGenie] +synonym: "Fumigacin breakdown" RELATED [GOC:TermGenie] +synonym: "Fumigacin catabolic process" RELATED [GOC:TermGenie] +synonym: "Fumigacin catabolism" RELATED [GOC:TermGenie] +synonym: "Fumigacin degradation" RELATED [GOC:TermGenie] +synonym: "helvolic acid breakdown" EXACT [GOC:TermGenie] +synonym: "helvolic acid catabolism" EXACT [GOC:TermGenie] +synonym: "helvolic acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900810 ! helvolic acid metabolic process +created_by: di +creation_date: 2012-06-04T10:02:51Z + +[Term] +id: GO:1900812 +name: helvolic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of helvolic acid." [GOC:di, GOC:TermGenie] +synonym: "Fumigacin anabolism" RELATED [GOC:TermGenie] +synonym: "Fumigacin biosynthesis" RELATED [GOC:TermGenie] +synonym: "Fumigacin biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Fumigacin formation" RELATED [GOC:TermGenie] +synonym: "Fumigacin synthesis" RELATED [GOC:TermGenie] +synonym: "helvolic acid anabolism" EXACT [GOC:TermGenie] +synonym: "helvolic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "helvolic acid formation" EXACT [GOC:TermGenie] +synonym: "helvolic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900810 ! helvolic acid metabolic process +created_by: di +creation_date: 2012-06-04T10:02:58Z + +[Term] +id: GO:1900813 +name: monodictyphenone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monodictyphenone." [GOC:di, GOC:TermGenie] +synonym: "monodictyphenone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: di +creation_date: 2012-06-04T10:11:03Z + +[Term] +id: GO:1900814 +name: monodictyphenone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monodictyphenone." [GOC:di, GOC:TermGenie] +synonym: "monodictyphenone breakdown" EXACT [GOC:TermGenie] +synonym: "monodictyphenone catabolism" EXACT [GOC:TermGenie] +synonym: "monodictyphenone degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900813 ! monodictyphenone metabolic process +created_by: di +creation_date: 2012-06-04T10:11:27Z + +[Term] +id: GO:1900815 +name: monodictyphenone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monodictyphenone." [GOC:di, GOC:TermGenie] +synonym: "monodictyphenone anabolism" EXACT [GOC:TermGenie] +synonym: "monodictyphenone biosynthesis" EXACT [GOC:TermGenie] +synonym: "monodictyphenone formation" EXACT [GOC:TermGenie] +synonym: "monodictyphenone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1900813 ! monodictyphenone metabolic process +created_by: di +creation_date: 2012-06-04T10:11:35Z + +[Term] +id: GO:1900816 +name: ochratoxin A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ochratoxin A." [GOC:di, GOC:TermGenie] +synonym: "Ochratoxin A metabolic process" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-06-04T10:13:02Z + +[Term] +id: GO:1900817 +name: ochratoxin A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ochratoxin A." [GOC:di, GOC:TermGenie] +synonym: "Ochratoxin A breakdown" EXACT [GOC:TermGenie] +synonym: "ochratoxin A breakdown" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A catabolic process" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A catabolism" EXACT [GOC:TermGenie] +synonym: "ochratoxin A catabolism" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A degradation" EXACT [GOC:TermGenie] +synonym: "ochratoxin A degradation" EXACT [GOC:TermGenie] +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900816 ! ochratoxin A metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-06-04T10:13:26Z + +[Term] +id: GO:1900818 +name: ochratoxin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ochratoxin A." [GOC:di, GOC:TermGenie] +synonym: "Ochratoxin A anabolism" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A biosynthesis" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A formation" EXACT [GOC:TermGenie] +synonym: "Ochratoxin A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1900816 ! ochratoxin A metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-06-04T10:13:32Z + +[Term] +id: GO:1900819 +name: orlandin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving orlandin." [GOC:di, GOC:TermGenie] +synonym: "orlandin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2012-06-04T10:14:55Z + +[Term] +id: GO:1900820 +name: orlandin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of orlandin." [GOC:di, GOC:TermGenie] +synonym: "orlandin breakdown" EXACT [GOC:TermGenie] +synonym: "orlandin catabolism" EXACT [GOC:TermGenie] +synonym: "orlandin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0090487 ! secondary metabolite catabolic process +is_a: GO:1900819 ! orlandin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: di +creation_date: 2012-06-04T10:15:17Z + +[Term] +id: GO:1900821 +name: orlandin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of orlandin." [GOC:di, GOC:TermGenie] +synonym: "orlandin anabolism" EXACT [GOC:TermGenie] +synonym: "orlandin biosynthesis" EXACT [GOC:TermGenie] +synonym: "orlandin formation" EXACT [GOC:TermGenie] +synonym: "orlandin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0044550 ! secondary metabolite biosynthetic process +is_a: GO:1900819 ! orlandin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: di +creation_date: 2012-06-04T10:15:24Z + +[Term] +id: GO:1900822 +name: regulation of ergot alkaloid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035837 ! ergot alkaloid biosynthetic process +relationship: regulates GO:0035837 ! ergot alkaloid biosynthetic process +created_by: di +creation_date: 2012-06-04T11:12:32Z + +[Term] +id: GO:1900823 +name: negative regulation of ergot alkaloid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ergot alkaloid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "inhibition of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900822 ! regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035837 ! ergot alkaloid biosynthetic process +relationship: negatively_regulates GO:0035837 ! ergot alkaloid biosynthetic process +created_by: di +creation_date: 2012-06-04T11:12:54Z + +[Term] +id: GO:1900824 +name: positive regulation of ergot alkaloid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "activation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of ergot alkaloid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "activation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ergot alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ergot alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ergot alkaloid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ergot alkaloid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ergot alkaloid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900822 ! regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035837 ! ergot alkaloid biosynthetic process +relationship: positively_regulates GO:0035837 ! ergot alkaloid biosynthetic process +created_by: di +creation_date: 2012-06-04T11:13:05Z + +[Term] +id: GO:1900825 +name: regulation of membrane depolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:TermGenie] +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:0098902 ! regulation of membrane depolarization during action potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +relationship: regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +created_by: rl +creation_date: 2012-06-06T04:15:20Z + +[Term] +id: GO:1900826 +name: negative regulation of membrane depolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:TermGenie] +synonym: "down regulation of membrane depolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane depolarization during of cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane depolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane depolarization during cardiac muscle cell action potential" NARROW [GOC:TermGenie] +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:1900825 ! regulation of membrane depolarization during cardiac muscle cell action potential +is_a: GO:1904180 ! negative regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +relationship: negatively_regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +created_by: rl +creation_date: 2012-06-06T04:15:40Z + +[Term] +id: GO:1900827 +name: positive regulation of membrane depolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:TermGenie] +synonym: "activation of membrane depolarization during cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up regulation of membrane depolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane depolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane depolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:1900825 ! regulation of membrane depolarization during cardiac muscle cell action potential +is_a: GO:1904181 ! positive regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +relationship: positively_regulates GO:0086012 ! membrane depolarization during cardiac muscle cell action potential +created_by: rl +creation_date: 2012-06-06T04:15:48Z + +[Term] +id: GO:1900828 +name: D-tyrosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-tyrosine." [GOC:TermGenie, PMID:10766779] +synonym: "D-tyrosine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006570 ! tyrosine metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process +created_by: se +creation_date: 2012-06-06T09:27:00Z + +[Term] +id: GO:1900829 +name: D-tyrosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-tyrosine." [GOC:TermGenie, PMID:10766779] +synonym: "D-tyrosine breakdown" EXACT [GOC:TermGenie] +synonym: "D-tyrosine catabolism" EXACT [GOC:TermGenie] +synonym: "D-tyrosine degradation" EXACT [GOC:TermGenie] +is_a: GO:0006572 ! tyrosine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:1900828 ! D-tyrosine metabolic process +created_by: se +creation_date: 2012-06-06T09:27:24Z + +[Term] +id: GO:1900830 +name: D-tyrosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-tyrosine." [GOC:TermGenie, PMID:10766779] +synonym: "D-tyrosine anabolism" EXACT [GOC:TermGenie] +synonym: "D-tyrosine biosynthesis" EXACT [GOC:TermGenie] +synonym: "D-tyrosine formation" EXACT [GOC:TermGenie] +synonym: "D-tyrosine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006571 ! tyrosine biosynthetic process +is_a: GO:0046437 ! D-amino acid biosynthetic process +is_a: GO:1900828 ! D-tyrosine metabolic process +created_by: se +creation_date: 2012-06-06T09:27:31Z + +[Term] +id: GO:1900831 +name: D-leucine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-leucine." [GOC:TermGenie, PMID:10918062] +synonym: "D-leucine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006551 ! leucine metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process +created_by: se +creation_date: 2012-06-06T09:37:17Z + +[Term] +id: GO:1900832 +name: D-leucine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-leucine." [GOC:TermGenie, PMID:10918062] +synonym: "D-leucine breakdown" EXACT [GOC:TermGenie] +synonym: "D-leucine catabolism" EXACT [GOC:TermGenie] +synonym: "D-leucine degradation" EXACT [GOC:TermGenie] +is_a: GO:0006552 ! leucine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:1900831 ! D-leucine metabolic process +created_by: se +creation_date: 2012-06-06T09:37:40Z + +[Term] +id: GO:1900833 +name: D-leucine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-leucine." [GOC:TermGenie, PMID:10918062] +synonym: "D-leucine anabolism" EXACT [GOC:TermGenie] +synonym: "D-leucine biosynthesis" EXACT [GOC:TermGenie] +synonym: "D-leucine formation" EXACT [GOC:TermGenie] +synonym: "D-leucine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009098 ! leucine biosynthetic process +is_a: GO:0046437 ! D-amino acid biosynthetic process +is_a: GO:1900831 ! D-leucine metabolic process +created_by: se +creation_date: 2012-06-06T09:37:47Z + +[Term] +id: GO:1900834 +name: regulation of emericellin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of emericellin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of emericellin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of emericellin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of emericellin formation" EXACT [GOC:TermGenie] +synonym: "regulation of emericellin synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of Variecoxanthone B anabolism" RELATED [GOC:TermGenie] +synonym: "regulation of Variecoxanthone B biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of Variecoxanthone B biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of Variecoxanthone B formation" RELATED [GOC:TermGenie] +synonym: "regulation of Variecoxanthone B synthesis" RELATED [GOC:TermGenie] +is_a: GO:1900183 ! regulation of xanthone-containing compound biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900766 ! emericellin biosynthetic process +relationship: regulates GO:1900766 ! emericellin biosynthetic process +created_by: di +creation_date: 2012-06-07T09:32:02Z + +[Term] +id: GO:1900835 +name: negative regulation of emericellin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of emericellin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of emericellin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of emericellin biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:1900184 ! negative regulation of xanthone-containing compound biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900834 ! regulation of emericellin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900766 ! emericellin biosynthetic process +relationship: negatively_regulates GO:1900766 ! emericellin biosynthetic process +created_by: di +creation_date: 2012-06-07T09:32:24Z + +[Term] +id: GO:1900836 +name: positive regulation of emericellin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process." [GOC:di, GOC:TermGenie] +is_a: GO:1900185 ! positive regulation of xanthone-containing compound biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900834 ! regulation of emericellin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900766 ! emericellin biosynthetic process +relationship: positively_regulates GO:1900766 ! emericellin biosynthetic process +created_by: di +creation_date: 2012-06-07T09:32:31Z + +[Term] +id: GO:1900837 +name: regulation of fumigaclavine C biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of fumigaclavine C anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of fumigaclavine C biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of fumigaclavine C formation" EXACT [GOC:TermGenie] +synonym: "regulation of fumigaclavine C synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900822 ! regulation of ergot alkaloid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900809 ! fumigaclavine C biosynthetic process +relationship: regulates GO:1900809 ! fumigaclavine C biosynthetic process +created_by: di +creation_date: 2012-06-07T09:36:22Z + +[Term] +id: GO:1900838 +name: negative regulation of fumigaclavine C biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "inhibition of fumigaclavine C biosynthetic process" NARROW [GOC:TermGenie] +is_a: GO:1900823 ! negative regulation of ergot alkaloid biosynthetic process +is_a: GO:1900837 ! regulation of fumigaclavine C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900809 ! fumigaclavine C biosynthetic process +relationship: negatively_regulates GO:1900809 ! fumigaclavine C biosynthetic process +created_by: di +creation_date: 2012-06-07T09:36:45Z + +[Term] +id: GO:1900839 +name: positive regulation of fumigaclavine C biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of fumigaclavine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumigaclavine C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of fumigaclavine C biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:1900824 ! positive regulation of ergot alkaloid biosynthetic process +is_a: GO:1900837 ! regulation of fumigaclavine C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900809 ! fumigaclavine C biosynthetic process +relationship: positively_regulates GO:1900809 ! fumigaclavine C biosynthetic process +created_by: di +creation_date: 2012-06-07T09:36:52Z + +[Term] +id: GO:1900840 +name: regulation of helvolic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process." [GOC:di, GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900812 ! helvolic acid biosynthetic process +relationship: regulates GO:1900812 ! helvolic acid biosynthetic process +created_by: di +creation_date: 2012-06-07T09:38:33Z + +[Term] +id: GO:1900841 +name: negative regulation of helvolic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900840 ! regulation of helvolic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900812 ! helvolic acid biosynthetic process +relationship: negatively_regulates GO:1900812 ! helvolic acid biosynthetic process +created_by: di +creation_date: 2012-06-07T09:38:57Z + +[Term] +id: GO:1900842 +name: positive regulation of helvolic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of helvolic acid biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900840 ! regulation of helvolic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900812 ! helvolic acid biosynthetic process +relationship: positively_regulates GO:1900812 ! helvolic acid biosynthetic process +created_by: di +creation_date: 2012-06-07T09:39:05Z + +[Term] +id: GO:1900843 +name: regulation of monodictyphenone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of monodictyphenone anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of monodictyphenone biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of monodictyphenone formation" EXACT [GOC:TermGenie] +synonym: "regulation of monodictyphenone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900815 ! monodictyphenone biosynthetic process +relationship: regulates GO:1900815 ! monodictyphenone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:40:38Z + +[Term] +id: GO:1900844 +name: negative regulation of monodictyphenone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of monodictyphenone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of monodictyphenone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of monodictyphenone biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900843 ! regulation of monodictyphenone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900815 ! monodictyphenone biosynthetic process +relationship: negatively_regulates GO:1900815 ! monodictyphenone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:41:00Z + +[Term] +id: GO:1900845 +name: positive regulation of monodictyphenone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "upregulation of monodictyphenone biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900843 ! regulation of monodictyphenone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900815 ! monodictyphenone biosynthetic process +relationship: positively_regulates GO:1900815 ! monodictyphenone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:41:08Z + +[Term] +id: GO:1900846 +name: regulation of naphtho-gamma-pyrone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrone anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrone biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrone formation" EXACT [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrone synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrones anabolism" RELATED [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrones biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrones biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrones formation" RELATED [GOC:TermGenie] +synonym: "regulation of naphtho-gamma-pyrones synthesis" RELATED [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +relationship: regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:42:41Z + +[Term] +id: GO:1900847 +name: negative regulation of naphtho-gamma-pyrone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of naphtho-gamma-pyrone biosynthetic process" NARROW [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900846 ! regulation of naphtho-gamma-pyrone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +relationship: negatively_regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:43:03Z + +[Term] +id: GO:1900848 +name: positive regulation of naphtho-gamma-pyrone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of naphtho-gamma-pyrone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of naphtho-gamma-pyrone biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900846 ! regulation of naphtho-gamma-pyrone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +relationship: positively_regulates GO:1900787 ! naphtho-gamma-pyrone biosynthetic process +created_by: di +creation_date: 2012-06-07T09:43:11Z + +[Term] +id: GO:1900849 +name: regulation of pseurotin A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of pseurotin A anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of pseurotin A biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of pseurotin A formation" EXACT [GOC:TermGenie] +synonym: "regulation of pseurotin A synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of Pseurotin anabolism" RELATED [GOC:TermGenie] +synonym: "regulation of Pseurotin biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of Pseurotin biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of Pseurotin formation" RELATED [GOC:TermGenie] +synonym: "regulation of Pseurotin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900790 ! pseurotin A biosynthetic process +relationship: regulates GO:1900790 ! pseurotin A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:45:27Z + +[Term] +id: GO:1900850 +name: negative regulation of pseurotin A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:1900849 ! regulation of pseurotin A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900790 ! pseurotin A biosynthetic process +relationship: negatively_regulates GO:1900790 ! pseurotin A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:45:49Z + +[Term] +id: GO:1900851 +name: positive regulation of pseurotin A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of pseurotin A biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:1900849 ! regulation of pseurotin A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900790 ! pseurotin A biosynthetic process +relationship: positively_regulates GO:1900790 ! pseurotin A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:45:56Z + +[Term] +id: GO:1900852 +name: regulation of terrequinone A biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of terrequinone A anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of terrequinone A biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of terrequinone A formation" EXACT [GOC:TermGenie] +synonym: "regulation of terrequinone A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900796 ! terrequinone A biosynthetic process +relationship: regulates GO:1900796 ! terrequinone A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:47:09Z + +[Term] +id: GO:1900853 +name: negative regulation of terrequinone A biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900852 ! regulation of terrequinone A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900796 ! terrequinone A biosynthetic process +relationship: negatively_regulates GO:1900796 ! terrequinone A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:47:30Z + +[Term] +id: GO:1900854 +name: positive regulation of terrequinone A biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of terrequinone A biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900852 ! regulation of terrequinone A biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900796 ! terrequinone A biosynthetic process +relationship: positively_regulates GO:1900796 ! terrequinone A biosynthetic process +created_by: di +creation_date: 2012-06-07T09:47:38Z + +[Term] +id: GO:1900855 +name: regulation of fumitremorgin B biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of fumitremorgin B anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of fumitremorgin B biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of fumitremorgin B formation" EXACT [GOC:TermGenie] +synonym: "regulation of fumitremorgin B synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of Lanosulin anabolism" RELATED [GOC:TermGenie] +synonym: "regulation of Lanosulin biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of Lanosulin biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of Lanosulin formation" RELATED [GOC:TermGenie] +synonym: "regulation of Lanosulin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900772 ! fumitremorgin B biosynthetic process +relationship: regulates GO:1900772 ! fumitremorgin B biosynthetic process +created_by: di +creation_date: 2012-06-07T09:50:37Z + +[Term] +id: GO:1900856 +name: negative regulation of fumitremorgin B biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900855 ! regulation of fumitremorgin B biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900772 ! fumitremorgin B biosynthetic process +relationship: negatively_regulates GO:1900772 ! fumitremorgin B biosynthetic process +created_by: di +creation_date: 2012-06-07T09:51:01Z + +[Term] +id: GO:1900857 +name: positive regulation of fumitremorgin B biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of fumitremorgin B biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900855 ! regulation of fumitremorgin B biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900772 ! fumitremorgin B biosynthetic process +relationship: positively_regulates GO:1900772 ! fumitremorgin B biosynthetic process +created_by: di +creation_date: 2012-06-07T09:51:09Z + +[Term] +id: GO:1900858 +name: regulation of brevianamide F biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of brevianamide F anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of brevianamide F biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of brevianamide F formation" EXACT [GOC:TermGenie] +synonym: "regulation of brevianamide F synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900805 ! brevianamide F biosynthetic process +relationship: regulates GO:1900805 ! brevianamide F biosynthetic process +created_by: di +creation_date: 2012-06-07T09:52:56Z + +[Term] +id: GO:1900859 +name: negative regulation of brevianamide F biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900858 ! regulation of brevianamide F biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900805 ! brevianamide F biosynthetic process +relationship: negatively_regulates GO:1900805 ! brevianamide F biosynthetic process +created_by: di +creation_date: 2012-06-07T09:53:17Z + +[Term] +id: GO:1900860 +name: positive regulation of brevianamide F biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "up regulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of brevianamide F biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900858 ! regulation of brevianamide F biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900805 ! brevianamide F biosynthetic process +relationship: positively_regulates GO:1900805 ! brevianamide F biosynthetic process +created_by: di +creation_date: 2012-06-07T09:53:25Z + +[Term] +id: GO:1900861 +name: regulation of cordyol C biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process." [GOC:di, GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900799 ! cordyol C biosynthetic process +relationship: regulates GO:1900799 ! cordyol C biosynthetic process +created_by: di +creation_date: 2012-06-07T01:56:16Z + +[Term] +id: GO:1900862 +name: negative regulation of cordyol C biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1900861 ! regulation of cordyol C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900799 ! cordyol C biosynthetic process +relationship: negatively_regulates GO:1900799 ! cordyol C biosynthetic process +created_by: di +creation_date: 2012-06-07T01:56:38Z + +[Term] +id: GO:1900863 +name: positive regulation of cordyol C biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of cordyol C biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cordyol C biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1900861 ! regulation of cordyol C biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900799 ! cordyol C biosynthetic process +relationship: positively_regulates GO:1900799 ! cordyol C biosynthetic process +created_by: di +creation_date: 2012-06-07T01:56:46Z + +[Term] +id: GO:1900864 +name: mitochondrial RNA modification +namespace: biological_process +def: "Any RNA modification that takes place in mitochondrion." [GOC:TermGenie] +synonym: "mitochondrial RNA editing" NARROW [GOC:TermGenie] +is_a: GO:0000959 ! mitochondrial RNA metabolic process +is_a: GO:0009451 ! RNA modification +intersection_of: GO:0009451 ! RNA modification +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: tb +creation_date: 2012-06-11T10:49:56Z + +[Term] +id: GO:1900865 +name: chloroplast RNA modification +namespace: biological_process +def: "Any RNA modification that takes place in chloroplast." [GOC:TermGenie] +synonym: "RNA editing in chloroplast" NARROW [GOC:TermGenie] +is_a: GO:0009451 ! RNA modification +intersection_of: GO:0009451 ! RNA modification +intersection_of: occurs_in GO:0009507 ! chloroplast +relationship: occurs_in GO:0009507 ! chloroplast +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 +created_by: tb +creation_date: 2012-06-11T10:58:04Z + +[Term] +id: GO:1900866 +name: glycolate transport +namespace: biological_process +def: "The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:pr, GOC:TermGenie] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015850 ! organic hydroxy compound transport +is_a: GO:0015893 ! drug transport +created_by: pr +creation_date: 2012-06-12T04:29:56Z + +[Term] +id: GO:1900867 +name: sarcinapterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sarcinapterin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "sarcinapterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:2001115 ! methanopterin-containing compound metabolic process +created_by: tt +creation_date: 2012-06-12T04:34:10Z + +[Term] +id: GO:1900868 +name: sarcinapterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sarcinapterin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "sarcinapterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process +is_a: GO:1900867 ! sarcinapterin metabolic process +is_a: GO:2001116 ! methanopterin-containing compound biosynthetic process +created_by: tt +creation_date: 2012-06-12T04:34:33Z + +[Term] +id: GO:1900869 +name: tatiopterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tatiopterin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "tatiopterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process +created_by: tt +creation_date: 2012-06-12T04:43:57Z + +[Term] +id: GO:1900870 +name: tatiopterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tatiopterin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "tatiopterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1900869 ! tatiopterin metabolic process +created_by: tt +creation_date: 2012-06-12T04:44:19Z + +[Term] +id: GO:1900871 +name: chloroplast mRNA modification +namespace: biological_process +def: "The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:TermGenie, PMID:1653905] +synonym: "chloroplast mRNA editing" NARROW [] +synonym: "mRNA editing in chloroplast" NARROW [GOC:TermGenie] +is_a: GO:0016556 ! mRNA modification +is_a: GO:1900865 ! chloroplast RNA modification +intersection_of: GO:0016556 ! mRNA modification +intersection_of: occurs_in GO:0009507 ! chloroplast +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 +created_by: dhl +creation_date: 2012-06-12T06:13:58Z + +[Term] +id: GO:1900872 +name: pentadec-1-ene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "pentadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-06-13T01:45:22Z + +[Term] +id: GO:1900873 +name: pentadec-1-ene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pentadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "pentadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "pentadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "pentadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "pentadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900872 ! pentadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-13T01:45:45Z + +[Term] +id: GO:1900874 +name: heptadec-1-ene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving heptadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "heptadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042810 ! pheromone metabolic process +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-06-13T01:49:51Z + +[Term] +id: GO:1900875 +name: heptadec-1-ene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of heptadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "heptadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "heptadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "heptadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "heptadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042811 ! pheromone biosynthetic process +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900874 ! heptadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-13T01:50:11Z + +[Term] +id: GO:1900876 +name: nonadec-1-ene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-06-13T01:52:09Z + +[Term] +id: GO:1900877 +name: nonadec-1-ene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900876 ! nonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-13T01:52:37Z + +[Term] +id: GO:1900878 +name: (Z)-nonadeca-1,14-diene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "(Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900673 ! olefin metabolic process +created_by: tt +creation_date: 2012-06-13T02:09:18Z + +[Term] +id: GO:1900879 +name: (Z)-nonadeca-1,14-diene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "(Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "(Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "(Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "(Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900674 ! olefin biosynthetic process +is_a: GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +created_by: tt +creation_date: 2012-06-13T02:09:39Z + +[Term] +id: GO:1900880 +name: 18-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 18-methylnonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-06-13T02:26:28Z + +[Term] +id: GO:1900881 +name: 18-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900880 ! 18-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-13T02:26:55Z + +[Term] +id: GO:1900882 +name: 17-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 17-methylnonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2012-06-13T02:35:37Z + +[Term] +id: GO:1900883 +name: 17-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1900882 ! 17-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-13T02:35:59Z + +[Term] +id: GO:1900884 +name: regulation of tridecane biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tridecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "regulation of tridecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900893 ! regulation of tridecane metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900632 ! tridecane biosynthetic process +relationship: regulates GO:1900632 ! tridecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:00:31Z + +[Term] +id: GO:1900885 +name: negative regulation of tridecane biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "down regulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tridecane anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of tridecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of tridecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tridecane formation" NARROW [GOC:TermGenie] +synonym: "inhibition of tridecane synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tridecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900884 ! regulation of tridecane biosynthetic process +is_a: GO:1900894 ! negative regulation of tridecane metabolic process +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900632 ! tridecane biosynthetic process +relationship: negatively_regulates GO:1900632 ! tridecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:00:53Z + +[Term] +id: GO:1900886 +name: positive regulation of tridecane biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tridecane anabolism" NARROW [GOC:TermGenie] +synonym: "activation of tridecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of tridecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tridecane formation" NARROW [GOC:TermGenie] +synonym: "activation of tridecane synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900884 ! regulation of tridecane biosynthetic process +is_a: GO:1900895 ! positive regulation of tridecane metabolic process +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900632 ! tridecane biosynthetic process +relationship: positively_regulates GO:1900632 ! tridecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:01:01Z + +[Term] +id: GO:1900887 +name: regulation of pentadecane biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of pentadecane anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of pentadecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of pentadecane formation" EXACT [GOC:TermGenie] +synonym: "regulation of pentadecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900890 ! regulation of pentadecane metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900634 ! pentadecane biosynthetic process +relationship: regulates GO:1900634 ! pentadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:03:32Z + +[Term] +id: GO:1900888 +name: negative regulation of pentadecane biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "down regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "downregulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of pentadecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of pentadecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "inhibition of pentadecane synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +is_a: GO:1900887 ! regulation of pentadecane biosynthetic process +is_a: GO:1900891 ! negative regulation of pentadecane metabolic process +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900634 ! pentadecane biosynthetic process +relationship: negatively_regulates GO:1900634 ! pentadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:03:57Z + +[Term] +id: GO:1900889 +name: positive regulation of pentadecane biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of pentadecane anabolism" NARROW [GOC:TermGenie] +synonym: "activation of pentadecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of pentadecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of pentadecane formation" NARROW [GOC:TermGenie] +synonym: "activation of pentadecane synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "up regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of pentadecane synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of pentadecane anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of pentadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of pentadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of pentadecane formation" RELATED [GOC:TermGenie] +synonym: "upregulation of pentadecane synthesis" RELATED [GOC:TermGenie] +is_a: GO:1900887 ! regulation of pentadecane biosynthetic process +is_a: GO:1900892 ! positive regulation of pentadecane metabolic process +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900634 ! pentadecane biosynthetic process +relationship: positively_regulates GO:1900634 ! pentadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:04:04Z + +[Term] +id: GO:1900890 +name: regulation of pentadecane metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pentadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of pentadecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900633 ! pentadecane metabolic process +relationship: regulates GO:1900633 ! pentadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:05:48Z + +[Term] +id: GO:1900891 +name: negative regulation of pentadecane metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of pentadecane metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of pentadecane metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900890 ! regulation of pentadecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900633 ! pentadecane metabolic process +relationship: negatively_regulates GO:1900633 ! pentadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:06:11Z + +[Term] +id: GO:1900892 +name: positive regulation of pentadecane metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of pentadecane metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of pentadecane metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of pentadecane metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of pentadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of pentadecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900890 ! regulation of pentadecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900633 ! pentadecane metabolic process +relationship: positively_regulates GO:1900633 ! pentadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:06:20Z + +[Term] +id: GO:1900893 +name: regulation of tridecane metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tridecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tridecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900631 ! tridecane metabolic process +relationship: regulates GO:1900631 ! tridecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:14:40Z + +[Term] +id: GO:1900894 +name: negative regulation of tridecane metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of tridecane metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tridecane metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of tridecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900893 ! regulation of tridecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900631 ! tridecane metabolic process +relationship: negatively_regulates GO:1900631 ! tridecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:15:03Z + +[Term] +id: GO:1900895 +name: positive regulation of tridecane metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tridecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tridecane metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tridecane metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tridecane metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of tridecane metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tridecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900893 ! regulation of tridecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900631 ! tridecane metabolic process +relationship: positively_regulates GO:1900631 ! tridecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:15:11Z + +[Term] +id: GO:1900896 +name: regulation of heptadecane biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of heptadecane anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of heptadecane biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of heptadecane formation" EXACT [GOC:TermGenie] +synonym: "regulation of heptadecane synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900899 ! regulation of heptadecane metabolic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900636 ! heptadecane biosynthetic process +relationship: regulates GO:1900636 ! heptadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:27:38Z + +[Term] +id: GO:1900897 +name: negative regulation of heptadecane biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "down regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "downregulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of heptadecane anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of heptadecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of heptadecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of heptadecane formation" NARROW [GOC:TermGenie] +synonym: "inhibition of heptadecane synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +is_a: GO:1900896 ! regulation of heptadecane biosynthetic process +is_a: GO:1900900 ! negative regulation of heptadecane metabolic process +is_a: GO:1901578 ! negative regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900636 ! heptadecane biosynthetic process +relationship: negatively_regulates GO:1900636 ! heptadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:28:02Z + +[Term] +id: GO:1900898 +name: positive regulation of heptadecane biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of heptadecane anabolism" NARROW [GOC:TermGenie] +synonym: "activation of heptadecane biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of heptadecane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of heptadecane formation" NARROW [GOC:TermGenie] +synonym: "activation of heptadecane synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "up regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of heptadecane synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of heptadecane anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of heptadecane biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of heptadecane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of heptadecane formation" RELATED [GOC:TermGenie] +synonym: "upregulation of heptadecane synthesis" RELATED [GOC:TermGenie] +is_a: GO:1900896 ! regulation of heptadecane biosynthetic process +is_a: GO:1900901 ! positive regulation of heptadecane metabolic process +is_a: GO:1901579 ! positive regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900636 ! heptadecane biosynthetic process +relationship: positively_regulates GO:1900636 ! heptadecane biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:28:10Z + +[Term] +id: GO:1900899 +name: regulation of heptadecane metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heptadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of heptadecane metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900635 ! heptadecane metabolic process +relationship: regulates GO:1900635 ! heptadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:30:03Z + +[Term] +id: GO:1900900 +name: negative regulation of heptadecane metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of heptadecane metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of heptadecane metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900899 ! regulation of heptadecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900635 ! heptadecane metabolic process +relationship: negatively_regulates GO:1900635 ! heptadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:30:25Z + +[Term] +id: GO:1900901 +name: positive regulation of heptadecane metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of heptadecane metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of heptadecane metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of heptadecane metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of heptadecane metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of heptadecane metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900899 ! regulation of heptadecane metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900635 ! heptadecane metabolic process +relationship: positively_regulates GO:1900635 ! heptadecane metabolic process +created_by: tt +creation_date: 2012-06-13T03:30:33Z + +[Term] +id: GO:1900902 +name: regulation of hexadecanal biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of hexadecanal anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of hexadecanal biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hexadecanal formation" EXACT [GOC:TermGenie] +synonym: "regulation of hexadecanal synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of palmitaldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of palmitaldehyde biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900905 ! regulation of hexadecanal metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006634 ! hexadecanal biosynthetic process +relationship: regulates GO:0006634 ! hexadecanal biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:33:10Z + +[Term] +id: GO:1900903 +name: negative regulation of hexadecanal biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "down regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "downregulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of hexadecanal anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of hexadecanal biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hexadecanal biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hexadecanal formation" NARROW [GOC:TermGenie] +synonym: "inhibition of hexadecanal synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of palmitaldehyde biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of palmitaldehyde biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900902 ! regulation of hexadecanal biosynthetic process +is_a: GO:1900906 ! negative regulation of hexadecanal metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006634 ! hexadecanal biosynthetic process +relationship: negatively_regulates GO:0006634 ! hexadecanal biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:33:34Z + +[Term] +id: GO:1900904 +name: positive regulation of hexadecanal biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of hexadecanal anabolism" NARROW [GOC:TermGenie] +synonym: "activation of hexadecanal biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of hexadecanal biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of hexadecanal formation" NARROW [GOC:TermGenie] +synonym: "activation of hexadecanal synthesis" NARROW [GOC:TermGenie] +synonym: "activation of palmitaldehyde biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "up regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of hexadecanal anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of hexadecanal biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of hexadecanal biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hexadecanal formation" RELATED [GOC:TermGenie] +synonym: "upregulation of hexadecanal synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of palmitaldehyde biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of palmitaldehyde biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900902 ! regulation of hexadecanal biosynthetic process +is_a: GO:1900907 ! positive regulation of hexadecanal metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006634 ! hexadecanal biosynthetic process +relationship: positively_regulates GO:0006634 ! hexadecanal biosynthetic process +created_by: tt +creation_date: 2012-06-13T03:33:42Z + +[Term] +id: GO:1900905 +name: regulation of hexadecanal metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hexadecanal metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of hexadecanal metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046458 ! hexadecanal metabolic process +relationship: regulates GO:0046458 ! hexadecanal metabolic process +created_by: tt +creation_date: 2012-06-13T03:35:27Z + +[Term] +id: GO:1900906 +name: negative regulation of hexadecanal metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of hexadecanal metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900905 ! regulation of hexadecanal metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046458 ! hexadecanal metabolic process +relationship: negatively_regulates GO:0046458 ! hexadecanal metabolic process +created_by: tt +creation_date: 2012-06-13T03:35:54Z + +[Term] +id: GO:1900907 +name: positive regulation of hexadecanal metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of hexadecanal metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of hexadecanal metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of hexadecanal metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hexadecanal metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900905 ! regulation of hexadecanal metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046458 ! hexadecanal metabolic process +relationship: positively_regulates GO:0046458 ! hexadecanal metabolic process +created_by: tt +creation_date: 2012-06-13T03:36:02Z + +[Term] +id: GO:1900908 +name: regulation of olefin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of olefin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of olefin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900673 ! olefin metabolic process +relationship: regulates GO:1900673 ! olefin metabolic process +created_by: tt +creation_date: 2012-06-13T04:18:29Z + +[Term] +id: GO:1900909 +name: negative regulation of olefin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of olefin metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of olefin metabolism" RELATED [GOC:TermGenie] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900673 ! olefin metabolic process +relationship: negatively_regulates GO:1900673 ! olefin metabolic process +created_by: tt +creation_date: 2012-06-13T04:18:50Z + +[Term] +id: GO:1900910 +name: positive regulation of olefin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of olefin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of olefin metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of olefin metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of olefin metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of olefin metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of olefin metabolism" RELATED [GOC:TermGenie] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900673 ! olefin metabolic process +relationship: positively_regulates GO:1900673 ! olefin metabolic process +created_by: tt +creation_date: 2012-06-13T04:18:58Z + +[Term] +id: GO:1900911 +name: regulation of olefin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of olefin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of olefin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of olefin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of olefin formation" EXACT [GOC:TermGenie] +synonym: "regulation of olefin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900674 ! olefin biosynthetic process +relationship: regulates GO:1900674 ! olefin biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:20:08Z + +[Term] +id: GO:1900912 +name: negative regulation of olefin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "down regulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "downregulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of olefin anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of olefin biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of olefin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of olefin formation" NARROW [GOC:TermGenie] +synonym: "inhibition of olefin synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of olefin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900674 ! olefin biosynthetic process +relationship: negatively_regulates GO:1900674 ! olefin biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:20:30Z + +[Term] +id: GO:1900913 +name: positive regulation of olefin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of olefin anabolism" NARROW [GOC:TermGenie] +synonym: "activation of olefin biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of olefin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of olefin formation" NARROW [GOC:TermGenie] +synonym: "activation of olefin synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "up regulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of olefin synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of olefin anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of olefin biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of olefin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of olefin formation" RELATED [GOC:TermGenie] +synonym: "upregulation of olefin synthesis" RELATED [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900674 ! olefin biosynthetic process +relationship: positively_regulates GO:1900674 ! olefin biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:20:38Z + +[Term] +id: GO:1900914 +name: regulation of octadecene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of octadecene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 1-octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of octadecene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of octadecene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of octadecene formation" EXACT [GOC:TermGenie] +synonym: "regulation of octadecene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900917 ! regulation of octadecene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900682 ! octadecene biosynthetic process +relationship: regulates GO:1900682 ! octadecene biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:24:24Z + +[Term] +id: GO:1900915 +name: negative regulation of octadecene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "down regulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "downregulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of 1-octadecene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene formation" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of octadecene synthesis" RELATED [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900914 ! regulation of octadecene biosynthetic process +is_a: GO:1900918 ! negative regulation of octadecene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900682 ! octadecene biosynthetic process +relationship: negatively_regulates GO:1900682 ! octadecene biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:24:47Z + +[Term] +id: GO:1900916 +name: positive regulation of octadecene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "activation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of octadecene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "activation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "up regulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of octadecene synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of 1-octadecene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of octadecene anabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of octadecene biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of octadecene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of octadecene formation" RELATED [GOC:TermGenie] +synonym: "upregulation of octadecene synthesis" RELATED [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900914 ! regulation of octadecene biosynthetic process +is_a: GO:1900919 ! positive regulation of octadecene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900682 ! octadecene biosynthetic process +relationship: positively_regulates GO:1900682 ! octadecene biosynthetic process +created_by: tt +creation_date: 2012-06-13T04:24:55Z + +[Term] +id: GO:1900917 +name: regulation of octadecene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of octadecene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of octadecene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900681 ! octadecene metabolic process +relationship: regulates GO:1900681 ! octadecene metabolic process +created_by: tt +creation_date: 2012-06-13T04:26:11Z + +[Term] +id: GO:1900918 +name: negative regulation of octadecene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of octadecene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of octadecene metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of octadecene metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900917 ! regulation of octadecene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900681 ! octadecene metabolic process +relationship: negatively_regulates GO:1900681 ! octadecene metabolic process +created_by: tt +creation_date: 2012-06-13T04:26:34Z + +[Term] +id: GO:1900919 +name: positive regulation of octadecene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of octadecene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of octadecene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of octadecene metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of octadecene metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of octadecene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of octadecene metabolism" RELATED [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900917 ! regulation of octadecene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900681 ! octadecene metabolic process +relationship: positively_regulates GO:1900681 ! octadecene metabolic process +created_by: tt +creation_date: 2012-06-13T04:26:42Z + +[Term] +id: GO:1900923 +name: regulation of glycine import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycine import into a cell." [GOC:TermGenie] +synonym: "regulation of glycine import" BROAD [] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:0051580 ! regulation of neurotransmitter uptake +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903804 ! glycine import across plasma membrane +relationship: regulates GO:1903804 ! glycine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:40:11Z + +[Term] +id: GO:1900924 +name: negative regulation of glycine import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell." [GOC:TermGenie] +synonym: "down regulation of glycine import" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycine import" EXACT [GOC:TermGenie] +synonym: "downregulation of glycine import" EXACT [GOC:TermGenie] +synonym: "inhibition of glycine import" NARROW [GOC:TermGenie] +synonym: "negative regulation of glycine import" BROAD [] +is_a: GO:0051581 ! negative regulation of neurotransmitter uptake +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1900923 ! regulation of glycine import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903804 ! glycine import across plasma membrane +relationship: negatively_regulates GO:1903804 ! glycine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:40:32Z + +[Term] +id: GO:1900925 +name: positive regulation of glycine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycine import." [GOC:TermGenie] +synonym: "activation of glycine import" NARROW [GOC:TermGenie] +synonym: "positive regulation of glycine import" BROAD [] +synonym: "up regulation of glycine import" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycine import" EXACT [GOC:TermGenie] +synonym: "upregulation of glycine import" EXACT [GOC:TermGenie] +is_a: GO:0051582 ! positive regulation of neurotransmitter uptake +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1900923 ! regulation of glycine import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903804 ! glycine import across plasma membrane +relationship: positively_regulates GO:1903804 ! glycine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:40:40Z + +[Term] +id: GO:1900926 +name: regulation of L-threonine import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-threonine import into cell." [GOC:TermGenie] +synonym: "regulation of L-threonine import" BROAD [] +synonym: "regulation of L-threonine uptake" EXACT [GOC:TermGenie] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903807 ! L-threonine import across plasma membrane +relationship: regulates GO:1903807 ! L-threonine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:41:32Z + +[Term] +id: GO:1900927 +name: negative regulation of L-threonine import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell." [GOC:TermGenie] +synonym: "down regulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "down regulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "down-regulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "downregulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "downregulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "inhibition of L-threonine import" NARROW [GOC:TermGenie] +synonym: "inhibition of L-threonine uptake" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-threonine uptake" RELATED [GOC:TermGenie] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1900926 ! regulation of L-threonine import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903807 ! L-threonine import across plasma membrane +relationship: negatively_regulates GO:1903807 ! L-threonine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:41:52Z + +[Term] +id: GO:1900928 +name: positive regulation of L-threonine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-threonine import into cell." [GOC:TermGenie] +synonym: "activation of L-threonine import" NARROW [GOC:TermGenie] +synonym: "activation of L-threonine uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-threonine import" BROAD [] +synonym: "positive regulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "up regulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "up regulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "up-regulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-threonine uptake" RELATED [GOC:TermGenie] +synonym: "upregulation of L-threonine import" EXACT [GOC:TermGenie] +synonym: "upregulation of L-threonine uptake" RELATED [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1900926 ! regulation of L-threonine import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903807 ! L-threonine import across plasma membrane +relationship: positively_regulates GO:1903807 ! L-threonine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:42:00Z + +[Term] +id: GO:1900929 +name: regulation of L-tyrosine import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell." [GOC:TermGenie] +synonym: "regulation of L-tyrosine import" BROAD [] +synonym: "regulation of L-tyrosine uptake" EXACT [GOC:TermGenie] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903808 ! L-tyrosine import across plasma membrane +relationship: regulates GO:1903808 ! L-tyrosine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:42:52Z + +[Term] +id: GO:1900930 +name: negative regulation of L-tyrosine import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell." [GOC:TermGenie] +synonym: "down regulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "down regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "down-regulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "downregulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "downregulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "inhibition of L-tyrosine import" NARROW [GOC:TermGenie] +synonym: "inhibition of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "negative regulation of L-tyrosine import" BROAD [] +synonym: "negative regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1900929 ! regulation of L-tyrosine import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903808 ! L-tyrosine import across plasma membrane +relationship: negatively_regulates GO:1903808 ! L-tyrosine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:43:14Z + +[Term] +id: GO:1900931 +name: positive regulation of L-tyrosine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell." [GOC:TermGenie] +synonym: "activation of L-tyrosine import" NARROW [GOC:TermGenie] +synonym: "activation of L-tyrosine uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-tyrosine import" BROAD [] +synonym: "positive regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "up regulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "up regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "up-regulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +synonym: "upregulation of L-tyrosine import" EXACT [GOC:TermGenie] +synonym: "upregulation of L-tyrosine uptake" RELATED [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1900929 ! regulation of L-tyrosine import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903808 ! L-tyrosine import across plasma membrane +relationship: positively_regulates GO:1903808 ! L-tyrosine import across plasma membrane +created_by: al +creation_date: 2012-06-13T07:43:21Z + +[Term] +id: GO:1900932 +name: regulation of nonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900876 ! nonadec-1-ene metabolic process +relationship: regulates GO:1900876 ! nonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:11:28Z + +[Term] +id: GO:1900933 +name: negative regulation of nonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900932 ! regulation of nonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900876 ! nonadec-1-ene metabolic process +relationship: negatively_regulates GO:1900876 ! nonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:11:50Z + +[Term] +id: GO:1900934 +name: positive regulation of nonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of nonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900932 ! regulation of nonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900876 ! nonadec-1-ene metabolic process +relationship: positively_regulates GO:1900876 ! nonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:11:58Z + +[Term] +id: GO:1900935 +name: regulation of nonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900932 ! regulation of nonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900877 ! nonadec-1-ene biosynthetic process +relationship: regulates GO:1900877 ! nonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:13:34Z + +[Term] +id: GO:1900936 +name: negative regulation of nonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "downregulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "inhibition of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900933 ! negative regulation of nonadec-1-ene metabolic process +is_a: GO:1900935 ! regulation of nonadec-1-ene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900877 ! nonadec-1-ene biosynthetic process +relationship: negatively_regulates GO:1900877 ! nonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:13:56Z + +[Term] +id: GO:1900937 +name: positive regulation of nonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "activation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of nonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "activation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "upregulation of nonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900934 ! positive regulation of nonadec-1-ene metabolic process +is_a: GO:1900935 ! regulation of nonadec-1-ene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900877 ! nonadec-1-ene biosynthetic process +relationship: positively_regulates GO:1900877 ! nonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:14:04Z + +[Term] +id: GO:1900938 +name: regulation of (Z)-nonadeca-1,14-diene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +relationship: regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +created_by: tt +creation_date: 2012-06-14T03:15:37Z + +[Term] +id: GO:1900939 +name: negative regulation of (Z)-nonadeca-1,14-diene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900938 ! regulation of (Z)-nonadeca-1,14-diene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +relationship: negatively_regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +created_by: tt +creation_date: 2012-06-14T03:15:58Z + +[Term] +id: GO:1900940 +name: positive regulation of (Z)-nonadeca-1,14-diene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene metabolism" EXACT [GOC:TermGenie] +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900938 ! regulation of (Z)-nonadeca-1,14-diene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +relationship: positively_regulates GO:1900878 ! (Z)-nonadeca-1,14-diene metabolic process +created_by: tt +creation_date: 2012-06-14T03:16:05Z + +[Term] +id: GO:1900941 +name: regulation of (Z)-nonadeca-1,14-diene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900938 ! regulation of (Z)-nonadeca-1,14-diene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +relationship: regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:17:32Z + +[Term] +id: GO:1900942 +name: negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "down regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "downregulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene formation" NARROW [GOC:TermGenie] +synonym: "inhibition of (Z)-nonadeca-1,14-diene synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900939 ! negative regulation of (Z)-nonadeca-1,14-diene metabolic process +is_a: GO:1900941 ! regulation of (Z)-nonadeca-1,14-diene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +relationship: negatively_regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:17:54Z + +[Term] +id: GO:1900943 +name: positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene anabolism" NARROW [GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene formation" NARROW [GOC:TermGenie] +synonym: "activation of (Z)-nonadeca-1,14-diene synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "up regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene formation" EXACT [GOC:TermGenie] +synonym: "upregulation of (Z)-nonadeca-1,14-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900940 ! positive regulation of (Z)-nonadeca-1,14-diene metabolic process +is_a: GO:1900941 ! regulation of (Z)-nonadeca-1,14-diene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +relationship: positively_regulates GO:1900879 ! (Z)-nonadeca-1,14-diene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:18:01Z + +[Term] +id: GO:1900944 +name: regulation of isoprene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isoprene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of isoprene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043611 ! isoprene metabolic process +relationship: regulates GO:0043611 ! isoprene metabolic process +created_by: tt +creation_date: 2012-06-14T03:19:13Z + +[Term] +id: GO:1900945 +name: negative regulation of isoprene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 2-methyl-1,3-butadiene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 2-methyl-1,3-butadiene metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of hemiterpene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hemiterpene metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of isoprene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of isoprene metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoprene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900944 ! regulation of isoprene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043611 ! isoprene metabolic process +relationship: negatively_regulates GO:0043611 ! isoprene metabolic process +created_by: tt +creation_date: 2012-06-14T03:19:33Z + +[Term] +id: GO:1900946 +name: positive regulation of isoprene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isoprene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 2-methyl-1,3-butadiene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of 2-methyl-1,3-butadiene metabolism" NARROW [GOC:TermGenie] +synonym: "activation of hemiterpene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of hemiterpene metabolism" NARROW [GOC:TermGenie] +synonym: "activation of isoprene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of isoprene metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoprene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 2-methyl-1,3-butadiene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 2-methyl-1,3-butadiene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of hemiterpene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hemiterpene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of isoprene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of isoprene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900944 ! regulation of isoprene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043611 ! isoprene metabolic process +relationship: positively_regulates GO:0043611 ! isoprene metabolic process +created_by: tt +creation_date: 2012-06-14T03:19:41Z + +[Term] +id: GO:1900947 +name: regulation of isoprene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isoprene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900944 ! regulation of isoprene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043612 ! isoprene biosynthetic process +relationship: regulates GO:0043612 ! isoprene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:21:26Z + +[Term] +id: GO:1900948 +name: negative regulation of isoprene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of 2-methyl-1,3-butadiene biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of 2-methyl-1,3-butadiene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hemiterpene biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hemiterpene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of isoprene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900945 ! negative regulation of isoprene metabolic process +is_a: GO:1900947 ! regulation of isoprene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043612 ! isoprene biosynthetic process +relationship: negatively_regulates GO:0043612 ! isoprene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:21:47Z + +[Term] +id: GO:1900949 +name: positive regulation of isoprene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 2-methyl-1,3-butadiene biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of 2-methyl-1,3-butadiene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of hemiterpene biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of hemiterpene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of isoprene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 2-methyl-1,3-butadiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 2-methyl-1,3-butadiene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hemiterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hemiterpene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of isoprene biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900946 ! positive regulation of isoprene metabolic process +is_a: GO:1900947 ! regulation of isoprene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043612 ! isoprene biosynthetic process +relationship: positively_regulates GO:0043612 ! isoprene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:21:54Z + +[Term] +id: GO:1900950 +name: regulation of 18-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900953 ! regulation of 18-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +relationship: regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:23:34Z + +[Term] +id: GO:1900951 +name: negative regulation of 18-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900950 ! regulation of 18-methylnonadec-1-ene biosynthetic process +is_a: GO:1900954 ! negative regulation of 18-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +relationship: negatively_regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:23:55Z + +[Term] +id: GO:1900952 +name: positive regulation of 18-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900950 ! regulation of 18-methylnonadec-1-ene biosynthetic process +is_a: GO:1900955 ! positive regulation of 18-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +relationship: positively_regulates GO:1900881 ! 18-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:24:02Z + +[Term] +id: GO:1900953 +name: regulation of 18-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +relationship: regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:25:16Z + +[Term] +id: GO:1900954 +name: negative regulation of 18-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900953 ! regulation of 18-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +relationship: negatively_regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:25:37Z + +[Term] +id: GO:1900955 +name: positive regulation of 18-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 18-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900953 ! regulation of 18-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +relationship: positively_regulates GO:1900880 ! 18-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:25:44Z + +[Term] +id: GO:1900956 +name: regulation of 17-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900911 ! regulation of olefin biosynthetic process +is_a: GO:1900959 ! regulation of 17-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +relationship: regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:27:18Z + +[Term] +id: GO:1900957 +name: negative regulation of 17-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900912 ! negative regulation of olefin biosynthetic process +is_a: GO:1900956 ! regulation of 17-methylnonadec-1-ene biosynthetic process +is_a: GO:1900960 ! negative regulation of 17-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +relationship: negatively_regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:27:39Z + +[Term] +id: GO:1900958 +name: positive regulation of 17-methylnonadec-1-ene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene formation" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900913 ! positive regulation of olefin biosynthetic process +is_a: GO:1900956 ! regulation of 17-methylnonadec-1-ene biosynthetic process +is_a: GO:1900961 ! positive regulation of 17-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +relationship: positively_regulates GO:1900883 ! 17-methylnonadec-1-ene biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:27:46Z + +[Term] +id: GO:1900959 +name: regulation of 17-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:1900908 ! regulation of olefin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +relationship: regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:29:27Z + +[Term] +id: GO:1900960 +name: negative regulation of 17-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1900909 ! negative regulation of olefin metabolic process +is_a: GO:1900959 ! regulation of 17-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +relationship: negatively_regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:29:51Z + +[Term] +id: GO:1900961 +name: positive regulation of 17-methylnonadec-1-ene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 17-methylnonadec-1-ene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1900910 ! positive regulation of olefin metabolic process +is_a: GO:1900959 ! regulation of 17-methylnonadec-1-ene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +relationship: positively_regulates GO:1900882 ! 17-methylnonadec-1-ene metabolic process +created_by: tt +creation_date: 2012-06-14T03:29:59Z + +[Term] +id: GO:1900962 +name: regulation of methanophenazine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900965 ! regulation of methanophenazine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900630 ! methanophenazine biosynthetic process +relationship: regulates GO:1900630 ! methanophenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:53:15Z + +[Term] +id: GO:1900963 +name: negative regulation of methanophenazine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of methanophenazine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "inhibition of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900962 ! regulation of methanophenazine biosynthetic process +is_a: GO:1900966 ! negative regulation of methanophenazine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900630 ! methanophenazine biosynthetic process +relationship: negatively_regulates GO:1900630 ! methanophenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:53:38Z + +[Term] +id: GO:1900964 +name: positive regulation of methanophenazine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "activation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of methanophenazine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "activation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900962 ! regulation of methanophenazine biosynthetic process +is_a: GO:1900967 ! positive regulation of methanophenazine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900630 ! methanophenazine biosynthetic process +relationship: positively_regulates GO:1900630 ! methanophenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:53:46Z + +[Term] +id: GO:1900965 +name: regulation of methanophenazine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methanophenazine metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900629 ! methanophenazine metabolic process +relationship: regulates GO:1900629 ! methanophenazine metabolic process +created_by: tt +creation_date: 2012-06-14T03:55:26Z + +[Term] +id: GO:1900966 +name: negative regulation of methanophenazine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of methanophenazine metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900965 ! regulation of methanophenazine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900629 ! methanophenazine metabolic process +relationship: negatively_regulates GO:1900629 ! methanophenazine metabolic process +created_by: tt +creation_date: 2012-06-14T03:55:49Z + +[Term] +id: GO:1900967 +name: positive regulation of methanophenazine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methanophenazine metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methanophenazine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900965 ! regulation of methanophenazine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900629 ! methanophenazine metabolic process +relationship: positively_regulates GO:1900629 ! methanophenazine metabolic process +created_by: tt +creation_date: 2012-06-14T03:55:56Z + +[Term] +id: GO:1900968 +name: regulation of sarcinapterin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019220 ! regulation of phosphate metabolic process +is_a: GO:0042068 ! regulation of pteridine metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900867 ! sarcinapterin metabolic process +relationship: regulates GO:1900867 ! sarcinapterin metabolic process +created_by: tt +creation_date: 2012-06-14T03:58:11Z + +[Term] +id: GO:1900969 +name: negative regulation of sarcinapterin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of sarcinapterin metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045863 ! negative regulation of pteridine metabolic process +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900968 ! regulation of sarcinapterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900867 ! sarcinapterin metabolic process +relationship: negatively_regulates GO:1900867 ! sarcinapterin metabolic process +created_by: tt +creation_date: 2012-06-14T03:58:35Z + +[Term] +id: GO:1900970 +name: positive regulation of sarcinapterin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of sarcinapterin metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045864 ! positive regulation of pteridine metabolic process +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900968 ! regulation of sarcinapterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900867 ! sarcinapterin metabolic process +relationship: positively_regulates GO:1900867 ! sarcinapterin metabolic process +created_by: tt +creation_date: 2012-06-14T03:58:43Z + +[Term] +id: GO:1900971 +name: regulation of sarcinapterin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900968 ! regulation of sarcinapterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900868 ! sarcinapterin biosynthetic process +relationship: regulates GO:1900868 ! sarcinapterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T03:59:44Z + +[Term] +id: GO:1900972 +name: negative regulation of sarcinapterin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sarcinapterin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900969 ! negative regulation of sarcinapterin metabolic process +is_a: GO:1900971 ! regulation of sarcinapterin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900868 ! sarcinapterin biosynthetic process +relationship: negatively_regulates GO:1900868 ! sarcinapterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:00:06Z + +[Term] +id: GO:1900973 +name: positive regulation of sarcinapterin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of sarcinapterin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "activation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of sarcinapterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900970 ! positive regulation of sarcinapterin metabolic process +is_a: GO:1900971 ! regulation of sarcinapterin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900868 ! sarcinapterin biosynthetic process +relationship: positively_regulates GO:1900868 ! sarcinapterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:00:14Z + +[Term] +id: GO:1900974 +name: regulation of tatiopterin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900977 ! regulation of tatiopterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900870 ! tatiopterin biosynthetic process +relationship: regulates GO:1900870 ! tatiopterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:01:42Z + +[Term] +id: GO:1900975 +name: negative regulation of tatiopterin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tatiopterin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900974 ! regulation of tatiopterin biosynthetic process +is_a: GO:1900978 ! negative regulation of tatiopterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900870 ! tatiopterin biosynthetic process +relationship: negatively_regulates GO:1900870 ! tatiopterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:02:06Z + +[Term] +id: GO:1900976 +name: positive regulation of tatiopterin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of tatiopterin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "activation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900974 ! regulation of tatiopterin biosynthetic process +is_a: GO:1900979 ! positive regulation of tatiopterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900870 ! tatiopterin biosynthetic process +relationship: positively_regulates GO:1900870 ! tatiopterin biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:02:14Z + +[Term] +id: GO:1900977 +name: regulation of tatiopterin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tatiopterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0051174 ! regulation of phosphorus metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900869 ! tatiopterin metabolic process +relationship: regulates GO:1900869 ! tatiopterin metabolic process +created_by: tt +creation_date: 2012-06-14T04:03:06Z + +[Term] +id: GO:1900978 +name: negative regulation of tatiopterin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tatiopterin metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010563 ! negative regulation of phosphorus metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900977 ! regulation of tatiopterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900869 ! tatiopterin metabolic process +relationship: negatively_regulates GO:1900869 ! tatiopterin metabolic process +created_by: tt +creation_date: 2012-06-14T04:03:29Z + +[Term] +id: GO:1900979 +name: positive regulation of tatiopterin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tatiopterin metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tatiopterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010562 ! positive regulation of phosphorus metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900977 ! regulation of tatiopterin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900869 ! tatiopterin metabolic process +relationship: positively_regulates GO:1900869 ! tatiopterin metabolic process +created_by: tt +creation_date: 2012-06-14T04:03:37Z + +[Term] +id: GO:1900980 +name: regulation of phenazine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002047 ! phenazine biosynthetic process +relationship: regulates GO:0002047 ! phenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:04:39Z + +[Term] +id: GO:1900981 +name: negative regulation of phenazine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of phenazine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1900980 ! regulation of phenazine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002047 ! phenazine biosynthetic process +relationship: negatively_regulates GO:0002047 ! phenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:05:03Z + +[Term] +id: GO:1900982 +name: positive regulation of phenazine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of phenazine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of acridizine biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of acridizine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of azophenylene biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of azophenylene biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of dibenzo-p-diazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of dibenzo-p-diazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of dibenzopyrazine biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of dibenzopyrazine biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of phenazine biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1900980 ! regulation of phenazine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002047 ! phenazine biosynthetic process +relationship: positively_regulates GO:0002047 ! phenazine biosynthetic process +created_by: tt +creation_date: 2012-06-14T04:05:10Z + +[Term] +id: GO:1900983 +name: vindoline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vindoline." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5292, UniPathway:UPA00365] +synonym: "vindoline metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046447 ! terpenoid indole alkaloid metabolic process +is_a: GO:1900619 ! acetate ester metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: yaf +creation_date: 2012-06-14T09:16:29Z + +[Term] +id: GO:1900984 +name: vindoline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of vindoline." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5292, UniPathway:UPA00365] +synonym: "vindoline breakdown" EXACT [GOC:TermGenie] +synonym: "vindoline catabolism" EXACT [GOC:TermGenie] +synonym: "vindoline degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1900983 ! vindoline metabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +created_by: yaf +creation_date: 2012-06-14T09:16:56Z + +[Term] +id: GO:1900985 +name: vindoline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vindoline." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5292, UniPathway:UPA00365] +synonym: "vindoline anabolism" EXACT [GOC:TermGenie] +synonym: "vindoline biosynthesis" EXACT [GOC:TermGenie] +synonym: "vindoline formation" EXACT [GOC:TermGenie] +synonym: "vindoline synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009709 ! terpenoid indole alkaloid biosynthetic process +is_a: GO:1900620 ! acetate ester biosynthetic process +is_a: GO:1900983 ! vindoline metabolic process +is_a: GO:1901378 ! organic heteropentacyclic compound biosynthetic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process +created_by: yaf +creation_date: 2012-06-14T09:17:03Z + +[Term] +id: GO:1900986 +name: ajmaline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ajmaline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00310] +synonym: "ajmaline metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046447 ! terpenoid indole alkaloid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: yaf +creation_date: 2012-06-14T09:47:02Z + +[Term] +id: GO:1900987 +name: ajmaline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ajmaline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00310] +synonym: "ajmaline breakdown" EXACT [GOC:TermGenie] +synonym: "ajmaline catabolism" EXACT [GOC:TermGenie] +synonym: "ajmaline degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:1900986 ! ajmaline metabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +created_by: yaf +creation_date: 2012-06-14T09:47:26Z + +[Term] +id: GO:1900988 +name: ajmaline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ajmaline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00310] +synonym: "ajmaline anabolism" EXACT [GOC:TermGenie] +synonym: "ajmaline biosynthesis" EXACT [GOC:TermGenie] +synonym: "ajmaline formation" EXACT [GOC:TermGenie] +synonym: "ajmaline synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009709 ! terpenoid indole alkaloid biosynthetic process +is_a: GO:1900986 ! ajmaline metabolic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +created_by: yaf +creation_date: 2012-06-14T09:47:33Z + +[Term] +id: GO:1900989 +name: scopolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving scopolamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00725] +synonym: "scopolamine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046448 ! tropane alkaloid metabolic process +is_a: GO:0097176 ! epoxide metabolic process +created_by: yaf +creation_date: 2012-06-14T09:47:38Z + +[Term] +id: GO:1900990 +name: scopolamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of scopolamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00725] +synonym: "scopolamine breakdown" EXACT [GOC:TermGenie] +synonym: "scopolamine catabolism" EXACT [GOC:TermGenie] +synonym: "scopolamine degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900989 ! scopolamine metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: yaf +creation_date: 2012-06-14T09:48:00Z + +[Term] +id: GO:1900991 +name: scopolamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of scopolamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00725] +synonym: "scopolamine anabolism" EXACT [GOC:TermGenie] +synonym: "scopolamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "scopolamine formation" EXACT [GOC:TermGenie] +synonym: "scopolamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009710 ! tropane alkaloid biosynthetic process +is_a: GO:1900989 ! scopolamine metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: yaf +creation_date: 2012-06-14T09:48:07Z + +[Term] +id: GO:1900992 +name: (-)-secologanin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-secologanin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00328] +synonym: "(-)-secologanin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006081 ! cellular aldehyde metabolic process +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: yaf +creation_date: 2012-06-14T09:51:17Z + +[Term] +id: GO:1900993 +name: (-)-secologanin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-secologanin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00328] +synonym: "(-)-secologanin breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-secologanin catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-secologanin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016100 ! monoterpenoid catabolic process +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1900992 ! (-)-secologanin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901805 ! beta-glucoside catabolic process +created_by: yaf +creation_date: 2012-06-14T09:51:39Z + +[Term] +id: GO:1900994 +name: (-)-secologanin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-secologanin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00328] +synonym: "(-)-secologanin anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-secologanin biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-secologanin formation" EXACT [GOC:TermGenie] +synonym: "(-)-secologanin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016099 ! monoterpenoid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:1900992 ! (-)-secologanin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process +created_by: yaf +creation_date: 2012-06-14T09:51:46Z + +[Term] +id: GO:1900995 +name: ubiquinone-6 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2." [GOC:al, GOC:TermGenie] +is_a: GO:0048039 ! ubiquinone binding +created_by: bf +creation_date: 2012-06-14T02:49:15Z + +[Term] +id: GO:1900996 +name: benzene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00272] +synonym: "benzene breakdown" EXACT [GOC:TermGenie] +synonym: "benzene catabolism" EXACT [GOC:TermGenie] +synonym: "benzene degradation" EXACT [GOC:TermGenie] +is_a: GO:0018910 ! benzene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: yaf +creation_date: 2012-06-14T02:53:38Z + +[Term] +id: GO:1900997 +name: benzene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of benzene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00272] +synonym: "benzene anabolism" EXACT [GOC:TermGenie] +synonym: "benzene biosynthesis" EXACT [GOC:TermGenie] +synonym: "benzene formation" EXACT [GOC:TermGenie] +synonym: "benzene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018910 ! benzene metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: yaf +creation_date: 2012-06-14T02:54:01Z + +[Term] +id: GO:1900998 +name: nitrobenzene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nitrobenzene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00923] +synonym: "nitrobenzene breakdown" EXACT [GOC:TermGenie] +synonym: "nitrobenzene catabolism" EXACT [GOC:TermGenie] +synonym: "nitrobenzene degradation" EXACT [GOC:TermGenie] +is_a: GO:0018916 ! nitrobenzene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: yaf +creation_date: 2012-06-14T02:54:09Z + +[Term] +id: GO:1900999 +name: nitrobenzene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nitrobenzene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00923] +synonym: "nitrobenzene anabolism" EXACT [GOC:TermGenie] +synonym: "nitrobenzene biosynthesis" EXACT [GOC:TermGenie] +synonym: "nitrobenzene formation" EXACT [GOC:TermGenie] +synonym: "nitrobenzene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018916 ! nitrobenzene metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: yaf +creation_date: 2012-06-14T02:54:32Z + +[Term] +id: GO:1901000 +name: regulation of response to salt stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to salt stress." [GOC:TermGenie, PMID:22627139] +synonym: "regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "regulation of salinity response" EXACT [GOC:TermGenie] +is_a: GO:0047484 ! regulation of response to osmotic stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009651 ! response to salt stress +relationship: regulates GO:0009651 ! response to salt stress +created_by: dhl +creation_date: 2012-06-14T05:41:19Z + +[Term] +id: GO:1901001 +name: negative regulation of response to salt stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress." [GOC:TermGenie, PMID:22627139] +synonym: "down regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "down regulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "down regulation of salinity response" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of salinity response" EXACT [GOC:TermGenie] +synonym: "downregulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "downregulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "downregulation of salinity response" EXACT [GOC:TermGenie] +synonym: "inhibition of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "inhibition of response to salt stress" NARROW [GOC:TermGenie] +synonym: "inhibition of salinity response" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of salinity response" EXACT [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901000 ! regulation of response to salt stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009651 ! response to salt stress +relationship: negatively_regulates GO:0009651 ! response to salt stress +created_by: dhl +creation_date: 2012-06-14T05:41:43Z + +[Term] +id: GO:1901002 +name: positive regulation of response to salt stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to salt stress." [GOC:TermGenie, PMID:22627139] +synonym: "activation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "activation of response to salt stress" NARROW [GOC:TermGenie] +synonym: "activation of salinity response" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of salinity response" EXACT [GOC:TermGenie] +synonym: "up regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "up regulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "up regulation of salinity response" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of salinity response" EXACT [GOC:TermGenie] +synonym: "upregulation of response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "upregulation of response to salt stress" EXACT [GOC:TermGenie] +synonym: "upregulation of salinity response" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901000 ! regulation of response to salt stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009651 ! response to salt stress +relationship: positively_regulates GO:0009651 ! response to salt stress +created_by: dhl +creation_date: 2012-06-14T05:41:50Z + +[Term] +id: GO:1901003 +name: negative regulation of fermentation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fermentation." [GOC:TermGenie] +synonym: "down regulation of fermentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of fermentation" EXACT [GOC:TermGenie] +synonym: "downregulation of fermentation" EXACT [GOC:TermGenie] +synonym: "inhibition of fermentation" NARROW [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0043465 ! regulation of fermentation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006113 ! fermentation +relationship: negatively_regulates GO:0006113 ! fermentation +created_by: al +creation_date: 2012-06-15T08:21:31Z + +[Term] +id: GO:1901004 +name: ubiquinone-6 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2." [GOC:al, GOC:TermGenie, PMID:1409592] +synonym: "coenzyme Q6 metabolic process" EXACT [CHEBI:52971] +synonym: "coenzyme Q6 metabolism" EXACT [CHEBI:52971] +synonym: "ubiquinone-6 metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006743 ! ubiquinone metabolic process +created_by: bf +creation_date: 2012-06-15T09:59:28Z + +[Term] +id: GO:1901005 +name: ubiquinone-6 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ubiquinone-6." [GOC:TermGenie] +synonym: "ubiquinone-6 breakdown" EXACT [GOC:TermGenie] +synonym: "ubiquinone-6 catabolism" EXACT [GOC:TermGenie] +synonym: "ubiquinone-6 degradation" EXACT [GOC:TermGenie] +is_a: GO:0032322 ! ubiquinone catabolic process +is_a: GO:1901004 ! ubiquinone-6 metabolic process +created_by: bf +creation_date: 2012-06-15T09:59:51Z + +[Term] +id: GO:1901006 +name: ubiquinone-6 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ubiquinone-6." [GOC:TermGenie] +synonym: "ubiquinone-6 anabolism" EXACT [GOC:TermGenie] +synonym: "ubiquinone-6 biosynthesis" EXACT [GOC:TermGenie] +synonym: "ubiquinone-6 formation" EXACT [GOC:TermGenie] +synonym: "ubiquinone-6 synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006744 ! ubiquinone biosynthetic process +is_a: GO:1901004 ! ubiquinone-6 metabolic process +created_by: bf +creation_date: 2012-06-15T09:59:58Z + +[Term] +id: GO:1901007 +name: (S)-scoulerine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (S)-scoulerine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00319] +synonym: "(S)-scoulerine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +created_by: yaf +creation_date: 2012-06-15T10:45:48Z + +[Term] +id: GO:1901008 +name: (S)-scoulerine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00319] +synonym: "(S)-scoulerine breakdown" EXACT [GOC:TermGenie] +synonym: "(S)-scoulerine catabolism" EXACT [GOC:TermGenie] +synonym: "(S)-scoulerine degradation" EXACT [GOC:TermGenie] +is_a: GO:0071274 ! isoquinoline alkaloid catabolic process +is_a: GO:1901007 ! (S)-scoulerine metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:10Z + +[Term] +id: GO:1901009 +name: (S)-scoulerine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (S)-scoulerine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00319] +synonym: "(S)-scoulerine anabolism" EXACT [GOC:TermGenie] +synonym: "(S)-scoulerine biosynthesis" EXACT [GOC:TermGenie] +synonym: "(S)-scoulerine formation" EXACT [GOC:TermGenie] +synonym: "(S)-scoulerine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0033075 ! isoquinoline alkaloid biosynthetic process +is_a: GO:1901007 ! (S)-scoulerine metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:17Z + +[Term] +id: GO:1901010 +name: (S)-reticuline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (S)-reticuline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00306] +synonym: "(S)-reticuline metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046445 ! benzyl isoquinoline alkaloid metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:22Z + +[Term] +id: GO:1901011 +name: (S)-reticuline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (S)-reticuline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00306] +synonym: "(S)-reticuline breakdown" EXACT [GOC:TermGenie] +synonym: "(S)-reticuline catabolism" EXACT [GOC:TermGenie] +synonym: "(S)-reticuline degradation" EXACT [GOC:TermGenie] +is_a: GO:0071274 ! isoquinoline alkaloid catabolic process +is_a: GO:1901010 ! (S)-reticuline metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:45Z + +[Term] +id: GO:1901012 +name: (S)-reticuline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (S)-reticuline." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00306] +synonym: "(S)-reticuline anabolism" EXACT [GOC:TermGenie] +synonym: "(S)-reticuline biosynthesis" EXACT [GOC:TermGenie] +synonym: "(S)-reticuline formation" EXACT [GOC:TermGenie] +synonym: "(S)-reticuline synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009708 ! benzyl isoquinoline alkaloid biosynthetic process +is_a: GO:1901010 ! (S)-reticuline metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:52Z + +[Term] +id: GO:1901013 +name: 3alpha(S)-strictosidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3alpha(S)-strictosidine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00311] +synonym: "3alpha(S)-strictosidine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035834 ! indole alkaloid metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: yaf +creation_date: 2012-06-15T10:46:57Z + +[Term] +id: GO:1901014 +name: 3alpha(S)-strictosidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00311] +synonym: "3alpha(S)-strictosidine breakdown" EXACT [GOC:TermGenie] +synonym: "3alpha(S)-strictosidine catabolism" EXACT [GOC:TermGenie] +synonym: "3alpha(S)-strictosidine degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:1901013 ! 3alpha(S)-strictosidine metabolic process +is_a: GO:1901805 ! beta-glucoside catabolic process +created_by: yaf +creation_date: 2012-06-15T10:47:19Z + +[Term] +id: GO:1901015 +name: 3alpha(S)-strictosidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00311] +synonym: "3alpha(S)-strictosidine anabolism" EXACT [GOC:TermGenie] +synonym: "3alpha(S)-strictosidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "3alpha(S)-strictosidine formation" EXACT [GOC:TermGenie] +synonym: "3alpha(S)-strictosidine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:1901013 ! 3alpha(S)-strictosidine metabolic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process +created_by: yaf +creation_date: 2012-06-15T10:47:26Z + +[Term] +id: GO:1901016 +name: regulation of potassium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of potassium transporter activity" EXACT [GOC:TermGenie] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1901379 ! regulation of potassium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015079 ! potassium ion transmembrane transporter activity +relationship: regulates GO:0015079 ! potassium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T01:13:49Z + +[Term] +id: GO:1901017 +name: negative regulation of potassium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "down regulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "inhibition of potassium ion transmembrane transporter activity" NARROW [GOC:TermGenie] +synonym: "inhibition of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of potassium transporter activity" EXACT [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:1901380 ! negative regulation of potassium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015079 ! potassium ion transmembrane transporter activity +relationship: negatively_regulates GO:0015079 ! potassium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T01:14:10Z + +[Term] +id: GO:1901018 +name: positive regulation of potassium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +synonym: "activation of potassium ion transmembrane transporter activity" NARROW [GOC:TermGenie] +synonym: "activation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "up regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "up regulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium transporter activity" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium transporter activity" EXACT [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:1901381 ! positive regulation of potassium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015079 ! potassium ion transmembrane transporter activity +relationship: positively_regulates GO:0015079 ! potassium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T01:14:18Z + +[Term] +id: GO:1901019 +name: regulation of calcium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015085 ! calcium ion transmembrane transporter activity +relationship: regulates GO:0015085 ! calcium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T07:54:12Z + +[Term] +id: GO:1901020 +name: negative regulation of calcium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion transmembrane transporter activity" NARROW [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015085 ! calcium ion transmembrane transporter activity +relationship: negatively_regulates GO:0015085 ! calcium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T07:54:32Z + +[Term] +id: GO:1901021 +name: positive regulation of calcium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] +synonym: "activation of calcium ion transmembrane transporter activity" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015085 ! calcium ion transmembrane transporter activity +relationship: positively_regulates GO:0015085 ! calcium ion transmembrane transporter activity +created_by: rl +creation_date: 2012-06-15T07:54:40Z + +[Term] +id: GO:1901022 +name: 4-hydroxyphenylacetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-hydroxyphenylacetate." [GOC:TermGenie, GOC:yaf, MetaCyc:RXN-8505, UniPathway:UPA00208] +synonym: "4-hydroxyphenylacetate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +created_by: yaf +creation_date: 2012-06-18T02:31:37Z + +[Term] +id: GO:1901023 +name: 4-hydroxyphenylacetate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate." [GOC:TermGenie, GOC:yaf, MetaCyc:RXN-8505, UniPathway:UPA00208] +synonym: "4-hydroxyphenylacetate breakdown" EXACT [GOC:TermGenie] +synonym: "4-hydroxyphenylacetate catabolism" EXACT [GOC:TermGenie] +synonym: "4-hydroxyphenylacetate degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901022 ! 4-hydroxyphenylacetate metabolic process +created_by: yaf +creation_date: 2012-06-18T02:31:58Z + +[Term] +id: GO:1901024 +name: 4-hydroxyphenylacetate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate." [GOC:TermGenie, GOC:yaf, MetaCyc:RXN-8505, UniPathway:UPA00208] +synonym: "4-hydroxyphenylacetate anabolism" EXACT [GOC:TermGenie] +synonym: "4-hydroxyphenylacetate biosynthesis" EXACT [GOC:TermGenie] +synonym: "4-hydroxyphenylacetate formation" EXACT [GOC:TermGenie] +synonym: "4-hydroxyphenylacetate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901022 ! 4-hydroxyphenylacetate metabolic process +created_by: yaf +creation_date: 2012-06-18T02:32:06Z + +[Term] +id: GO:1901025 +name: ripoptosome assembly involved in extrinsic apoptotic signaling pathway +namespace: biological_process +def: "The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:22274400] +is_a: GO:0097343 ! ripoptosome assembly +intersection_of: GO:0097343 ! ripoptosome assembly +intersection_of: part_of GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: part_of GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2012-06-19T08:49:33Z + +[Term] +id: GO:1901026 +name: ripoptosome assembly involved in necroptotic process +namespace: biological_process +def: "The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:22274400] +synonym: "ripoptosome assembly involved in necroptosis" NARROW [] +is_a: GO:0097343 ! ripoptosome assembly +intersection_of: GO:0097343 ! ripoptosome assembly +intersection_of: part_of GO:0070266 ! necroptotic process +relationship: part_of GO:0070266 ! necroptotic process +created_by: pr +creation_date: 2012-06-19T08:54:28Z + +[Term] +id: GO:1901027 +name: dextrin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of dextrin." [GOC:TermGenie] +synonym: "dextrin breakdown" EXACT [GOC:TermGenie] +synonym: "dextrin catabolism" EXACT [GOC:TermGenie] +synonym: "dextrin degradation" EXACT [GOC:TermGenie] +is_a: GO:0009251 ! glucan catabolic process +created_by: al +creation_date: 2012-06-19T03:12:19Z + +[Term] +id: GO:1901028 +name: regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "regulation of mitochondrial outer membrane permeabilization" BROAD [] +synonym: "regulation of MOMP" EXACT [GOC:TermGenie] +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:0046902 ! regulation of mitochondrial membrane permeability +is_a: GO:0051049 ! regulation of transport +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097345 ! mitochondrial outer membrane permeabilization +relationship: regulates GO:0097345 ! mitochondrial outer membrane permeabilization +created_by: pr +creation_date: 2012-06-20T09:19:16Z + +[Term] +id: GO:1901029 +name: negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie] +synonym: "down regulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "down regulation of MOMP" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "down-regulation of MOMP" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "downregulation of MOMP" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial outer membrane permeabilization" NARROW [GOC:TermGenie] +synonym: "inhibition of MOMP" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial outer membrane permeabilization" BROAD [] +synonym: "negative regulation of MOMP" EXACT [GOC:TermGenie] +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1901028 ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097345 ! mitochondrial outer membrane permeabilization +relationship: negatively_regulates GO:0097345 ! mitochondrial outer membrane permeabilization +created_by: pr +creation_date: 2012-06-20T09:19:39Z + +[Term] +id: GO:1901030 +name: positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie] +comment: Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID. +synonym: "activation of mitochondrial outer membrane permeabilization" NARROW [GOC:TermGenie] +synonym: "activation of MOMP" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial outer membrane permeabilization" BROAD [] +synonym: "positive regulation of MOMP" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "up regulation of MOMP" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "up-regulation of MOMP" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial outer membrane permeabilization" EXACT [GOC:TermGenie] +synonym: "upregulation of MOMP" EXACT [GOC:TermGenie] +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1901028 ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097345 ! mitochondrial outer membrane permeabilization +relationship: positively_regulates GO:0097345 ! mitochondrial outer membrane permeabilization +created_by: pr +creation_date: 2012-06-20T09:19:46Z + +[Term] +id: GO:1901031 +name: regulation of response to reactive oxygen species +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] +synonym: "regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "regulation of response to ROS" EXACT [GOC:TermGenie] +is_a: GO:1902882 ! regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000302 ! response to reactive oxygen species +relationship: regulates GO:0000302 ! response to reactive oxygen species +created_by: kmv +creation_date: 2012-06-20T07:47:06Z + +[Term] +id: GO:1901032 +name: negative regulation of response to reactive oxygen species +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] +synonym: "down regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "down regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "down regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "down regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "down regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "down regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "down regulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "downregulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "downregulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "downregulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "downregulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "downregulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "downregulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "downregulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "inhibition of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "inhibition of response to AOS" EXACT [GOC:TermGenie] +synonym: "inhibition of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "inhibition of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "inhibition of response to reactive oxygen species" NARROW [GOC:TermGenie] +synonym: "inhibition of response to ROI" EXACT [GOC:TermGenie] +synonym: "inhibition of response to ROS" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to ROS" EXACT [GOC:TermGenie] +is_a: GO:1901031 ! regulation of response to reactive oxygen species +is_a: GO:1902883 ! negative regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000302 ! response to reactive oxygen species +relationship: negatively_regulates GO:0000302 ! response to reactive oxygen species +created_by: kmv +creation_date: 2012-06-20T07:47:28Z + +[Term] +id: GO:1901033 +name: positive regulation of response to reactive oxygen species +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." [GOC:kmv, GOC:TermGenie] +synonym: "activation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "activation of response to AOS" EXACT [GOC:TermGenie] +synonym: "activation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "activation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "activation of response to reactive oxygen species" NARROW [GOC:TermGenie] +synonym: "activation of response to ROI" EXACT [GOC:TermGenie] +synonym: "activation of response to ROS" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "up regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "up regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "up regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "up regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "up regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "up regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "up regulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to ROS" EXACT [GOC:TermGenie] +synonym: "upregulation of response to active oxygen species" EXACT [GOC:TermGenie] +synonym: "upregulation of response to AOS" EXACT [GOC:TermGenie] +synonym: "upregulation of response to reactive oxidative species" EXACT [GOC:TermGenie] +synonym: "upregulation of response to reactive oxygen intermediate" EXACT [GOC:TermGenie] +synonym: "upregulation of response to reactive oxygen species" EXACT [GOC:TermGenie] +synonym: "upregulation of response to ROI" EXACT [GOC:TermGenie] +synonym: "upregulation of response to ROS" EXACT [GOC:TermGenie] +is_a: GO:1901031 ! regulation of response to reactive oxygen species +is_a: GO:1902884 ! positive regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000302 ! response to reactive oxygen species +relationship: positively_regulates GO:0000302 ! response to reactive oxygen species +created_by: kmv +creation_date: 2012-06-20T07:47:35Z + +[Term] +id: GO:1901034 +name: regulation of L-glutamine import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-glutamine import into cell." [GOC:TermGenie] +synonym: "regulation of L-glutamine import" BROAD [] +synonym: "regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2000485 ! regulation of glutamine transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903803 ! L-glutamine import across plasma membrane +relationship: regulates GO:1903803 ! L-glutamine import across plasma membrane +created_by: al +creation_date: 2012-06-21T07:31:27Z + +[Term] +id: GO:1901035 +name: negative regulation of L-glutamine import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell." [GOC:TermGenie] +synonym: "down regulation of L-glutamine import" EXACT [GOC:TermGenie] +synonym: "down regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-glutamine import" BROAD [GOC:TermGenie] +synonym: "down-regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "downregulation of L-glutamine import" EXACT [GOC:TermGenie] +synonym: "downregulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "inhibition of L-glutamine import" NARROW [GOC:TermGenie] +synonym: "inhibition of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-glutamine import" BROAD [] +synonym: "negative regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +is_a: GO:1901034 ! regulation of L-glutamine import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2000486 ! negative regulation of glutamine transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903803 ! L-glutamine import across plasma membrane +relationship: negatively_regulates GO:1903803 ! L-glutamine import across plasma membrane +created_by: al +creation_date: 2012-06-21T07:31:48Z + +[Term] +id: GO:1901036 +name: positive regulation of L-glutamine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell." [GOC:TermGenie] +synonym: "activation of L-glutamine import" NARROW [GOC:TermGenie] +synonym: "activation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-glutamine import" BROAD [] +synonym: "positive regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "up regulation of L-glutamine import" EXACT [GOC:TermGenie] +synonym: "up regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-glutamine import" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-glutamine uptake" EXACT [GOC:TermGenie] +synonym: "upregulation of L-glutamine import" EXACT [GOC:TermGenie] +synonym: "upregulation of L-glutamine uptake" EXACT [GOC:TermGenie] +is_a: GO:1901034 ! regulation of L-glutamine import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2000487 ! positive regulation of glutamine transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903803 ! L-glutamine import across plasma membrane +relationship: positively_regulates GO:1903803 ! L-glutamine import across plasma membrane +created_by: al +creation_date: 2012-06-21T07:31:56Z + +[Term] +id: GO:1901037 +name: obsolete regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that regulates transcription such that the target genes are transcribed during the M/G1 transition of the mitotic cell cycle." [GOC:mah, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:12411492] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "global transcription regulation from Pol II promoter during M/G1 transition of mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter during M/G1 transition of mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of transcription during M/G1 transition of mitotic cell cycle" BROAD [] +synonym: "regulation of transcription from Pol II promoter during M/G1 transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter involved in M/G1 transition of mitotic cell cycle" RELATED [] +is_obsolete: true +created_by: pr +creation_date: 2012-06-21T10:09:51Z + +[Term] +id: GO:1901038 +name: cyanidin 3-O-glucoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside." [GOC:TermGenie, PMID:21899608] +synonym: "cyanidin 3-O-beta-D-glucoside metabolic process" EXACT [] +synonym: "cyanidin 3-O-beta-D-glucoside metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009812 ! flavonoid metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: tb +creation_date: 2012-06-22T12:16:26Z + +[Term] +id: GO:1901039 +name: regulation of peptide antigen transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptide antigen transport." [GOC:bf, GOC:TermGenie] +is_a: GO:0002583 ! regulation of antigen processing and presentation of peptide antigen +is_a: GO:0090087 ! regulation of peptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046968 ! peptide antigen transport +relationship: regulates GO:0046968 ! peptide antigen transport +created_by: bf +creation_date: 2012-06-22T04:07:56Z + +[Term] +id: GO:1901040 +name: negative regulation of peptide antigen transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport." [GOC:bf, GOC:TermGenie, PMID:16691491] +synonym: "down regulation of peptide antigen transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptide antigen transport" EXACT [GOC:TermGenie] +synonym: "downregulation of peptide antigen transport" EXACT [GOC:TermGenie] +synonym: "inhibition of peptide antigen transport" NARROW [GOC:TermGenie] +is_a: GO:0002584 ! negative regulation of antigen processing and presentation of peptide antigen +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1901039 ! regulation of peptide antigen transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046968 ! peptide antigen transport +relationship: negatively_regulates GO:0046968 ! peptide antigen transport +created_by: bf +creation_date: 2012-06-22T04:08:18Z + +[Term] +id: GO:1901041 +name: positive regulation of peptide antigen transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptide antigen transport." [GOC:bf, GOC:TermGenie] +synonym: "activation of peptide antigen transport" NARROW [GOC:TermGenie] +synonym: "up regulation of peptide antigen transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptide antigen transport" EXACT [GOC:TermGenie] +synonym: "upregulation of peptide antigen transport" EXACT [GOC:TermGenie] +is_a: GO:0002585 ! positive regulation of antigen processing and presentation of peptide antigen +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1901039 ! regulation of peptide antigen transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046968 ! peptide antigen transport +relationship: positively_regulates GO:0046968 ! peptide antigen transport +created_by: bf +creation_date: 2012-06-22T04:08:26Z + +[Term] +id: GO:1901043 +name: obsolete protein polyubiquitination involved in cellular response to misfolded protein +namespace: biological_process +def: "OBSOLETE. Any protein polyubiquitination that is involved in cellular response to misfolded protein." [GOC:al, GOC:TermGenie, PMID:21324894] +comment: This term was made obsolete because it was added in error and a more specific term was created. +synonym: "polyubiquitin of cellular response to misfolded protein" RELATED [GOC:TermGenie] +synonym: "protein polyubiquitination involved in cellular response to misfolded protein" EXACT [] +synonym: "protein polyubiquitination of cellular response to misfolded protein" EXACT [GOC:TermGenie] +synonym: "protein polyubiquitinylation of cellular response to misfolded protein" EXACT [GOC:TermGenie] +synonym: "protein polyubiquitylation of cellular response to misfolded protein" EXACT [GOC:TermGenie] +is_obsolete: true +consider: GO:1901044 +created_by: al +creation_date: 2012-06-26T09:40:45Z + +[Term] +id: GO:1901044 +name: protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process." [GOC:al, GOC:TermGenie, PMID:21324894] +is_a: GO:0000209 ! protein polyubiquitination +intersection_of: GO:0000209 ! protein polyubiquitination +intersection_of: part_of GO:0071630 ! nuclear protein quality control by the ubiquitin-proteasome system +relationship: part_of GO:0071630 ! nuclear protein quality control by the ubiquitin-proteasome system +created_by: al +creation_date: 2012-06-26T10:59:04Z + +[Term] +id: GO:1901045 +name: negative regulation of oviposition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oviposition." [GOC:kmv, GOC:TermGenie] +synonym: "down regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "down regulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "down regulation of oviposition" EXACT [GOC:TermGenie] +synonym: "down-regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "down-regulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "down-regulation of oviposition" EXACT [GOC:TermGenie] +synonym: "downregulation of egg laying" BROAD [GOC:TermGenie] +synonym: "downregulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "downregulation of oviposition" EXACT [GOC:TermGenie] +synonym: "inhibition of egg laying" BROAD [GOC:TermGenie] +synonym: "inhibition of egg-laying" BROAD [GOC:TermGenie] +synonym: "inhibition of oviposition" NARROW [GOC:TermGenie] +synonym: "negative regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "negative regulation of egg-laying" BROAD [GOC:TermGenie] +is_a: GO:0046662 ! regulation of oviposition +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018991 ! oviposition +relationship: negatively_regulates GO:0018991 ! oviposition +created_by: kmv +creation_date: 2012-06-27T06:19:58Z + +[Term] +id: GO:1901046 +name: positive regulation of oviposition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oviposition." [GOC:kmv, GOC:TermGenie] +synonym: "activation of egg laying" BROAD [GOC:TermGenie] +synonym: "activation of egg-laying" BROAD [GOC:TermGenie] +synonym: "activation of oviposition" NARROW [GOC:TermGenie] +synonym: "positive regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "positive regulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "up regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "up regulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "up regulation of oviposition" EXACT [GOC:TermGenie] +synonym: "up-regulation of egg laying" BROAD [GOC:TermGenie] +synonym: "up-regulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "up-regulation of oviposition" EXACT [GOC:TermGenie] +synonym: "upregulation of egg laying" BROAD [GOC:TermGenie] +synonym: "upregulation of egg-laying" BROAD [GOC:TermGenie] +synonym: "upregulation of oviposition" EXACT [GOC:TermGenie] +is_a: GO:0046662 ! regulation of oviposition +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018991 ! oviposition +relationship: positively_regulates GO:0018991 ! oviposition +created_by: kmv +creation_date: 2012-06-27T06:20:20Z + +[Term] +id: GO:1901047 +name: insulin receptor signaling pathway involved in determination of adult lifespan +namespace: biological_process +def: "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle." [GOC:kmv, GOC:TermGenie, PMID:9360933] +synonym: "daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +is_a: GO:0008286 ! insulin receptor signaling pathway +intersection_of: GO:0008286 ! insulin receptor signaling pathway +intersection_of: part_of GO:0008340 ! determination of adult lifespan +relationship: part_of GO:0008340 ! determination of adult lifespan +created_by: kmv +creation_date: 2012-06-27T06:55:18Z + +[Term] +id: GO:1901048 +name: transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth +namespace: biological_process +def: "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:kmv, GOC:TermGenie, PMID:9847239] +synonym: "TGF-beta receptor signaling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signaling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signaling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signaling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signaling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway of regulation of body growth" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway of regulation of body size" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth" EXACT [GOC:TermGenie] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0040014 ! regulation of multicellular organism growth +relationship: part_of GO:0040014 ! regulation of multicellular organism growth +created_by: kmv +creation_date: 2012-06-27T07:37:22Z + +[Term] +id: GO:1901049 +name: atropine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving atropine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00303] +synonym: "atropine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +created_by: yaf +creation_date: 2012-06-28T04:51:25Z + +[Term] +id: GO:1901050 +name: atropine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of atropine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00303] +synonym: "atropine breakdown" EXACT [GOC:TermGenie] +synonym: "atropine catabolism" EXACT [GOC:TermGenie] +synonym: "atropine degradation" EXACT [GOC:TermGenie] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901049 ! atropine metabolic process +created_by: yaf +creation_date: 2012-06-28T04:51:51Z + +[Term] +id: GO:1901051 +name: atropine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of atropine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00303] +synonym: "atropine anabolism" EXACT [GOC:TermGenie] +synonym: "atropine biosynthesis" EXACT [GOC:TermGenie] +synonym: "atropine formation" EXACT [GOC:TermGenie] +synonym: "atropine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:1901049 ! atropine metabolic process +created_by: yaf +creation_date: 2012-06-28T04:51:59Z + +[Term] +id: GO:1901052 +name: sarcosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sarcosine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00292] +synonym: "sarcosine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: yaf +creation_date: 2012-06-28T04:52:04Z + +[Term] +id: GO:1901053 +name: sarcosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of sarcosine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00292] +synonym: "sarcosine breakdown" EXACT [GOC:TermGenie] +synonym: "sarcosine catabolism" EXACT [GOC:TermGenie] +synonym: "sarcosine degradation" EXACT [GOC:TermGenie] +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:1901052 ! sarcosine metabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +created_by: yaf +creation_date: 2012-06-28T04:52:29Z + +[Term] +id: GO:1901054 +name: sarcosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sarcosine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00292] +synonym: "sarcosine anabolism" EXACT [GOC:TermGenie] +synonym: "sarcosine biosynthesis" EXACT [GOC:TermGenie] +synonym: "sarcosine formation" EXACT [GOC:TermGenie] +synonym: "sarcosine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:1901052 ! sarcosine metabolic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +created_by: yaf +creation_date: 2012-06-28T04:52:37Z + +[Term] +id: GO:1901055 +name: trimethylenediamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving trimethylenediamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00010] +synonym: "trimethylenediamine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006595 ! polyamine metabolic process +created_by: yaf +creation_date: 2012-06-28T04:52:42Z + +[Term] +id: GO:1901056 +name: trimethylenediamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of trimethylenediamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00010] +synonym: "trimethylenediamine breakdown" EXACT [GOC:TermGenie] +synonym: "trimethylenediamine catabolism" EXACT [GOC:TermGenie] +synonym: "trimethylenediamine degradation" EXACT [GOC:TermGenie] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:1901055 ! trimethylenediamine metabolic process +created_by: yaf +creation_date: 2012-06-28T04:53:06Z + +[Term] +id: GO:1901057 +name: trimethylenediamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of trimethylenediamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00010] +synonym: "trimethylenediamine anabolism" EXACT [GOC:TermGenie] +synonym: "trimethylenediamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "trimethylenediamine formation" EXACT [GOC:TermGenie] +synonym: "trimethylenediamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:1901055 ! trimethylenediamine metabolic process +created_by: yaf +creation_date: 2012-06-28T04:53:14Z + +[Term] +id: GO:1901058 +name: p-hydroxyphenyl lignin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving p-hydroxyphenyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "H-lignin metabolic process" EXACT [GOC:mengo_curators] +synonym: "p-hydroxyphenyl lignin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009808 ! lignin metabolic process +created_by: tt +creation_date: 2012-06-29T12:31:57Z + +[Term] +id: GO:1901059 +name: p-hydroxyphenyl lignin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "H-lignin catabolic process" EXACT [GOC:mengo_curators] +synonym: "p-hydroxyphenyl lignin breakdown" EXACT [GOC:TermGenie] +synonym: "p-hydroxyphenyl lignin catabolism" EXACT [GOC:TermGenie] +synonym: "p-hydroxyphenyl lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0046274 ! lignin catabolic process +is_a: GO:1901058 ! p-hydroxyphenyl lignin metabolic process +created_by: tt +creation_date: 2012-06-29T12:32:17Z + +[Term] +id: GO:1901060 +name: p-hydroxyphenyl lignin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "H-lignin biosynthetic process" EXACT [GOC:mengo_curators] +synonym: "p-hydroxyphenyl lignin anabolism" EXACT [GOC:TermGenie] +synonym: "p-hydroxyphenyl lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "p-hydroxyphenyl lignin formation" EXACT [GOC:TermGenie] +synonym: "p-hydroxyphenyl lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009809 ! lignin biosynthetic process +is_a: GO:1901058 ! p-hydroxyphenyl lignin metabolic process +created_by: tt +creation_date: 2012-06-29T02:42:36Z + +[Term] +id: GO:1901061 +name: guaiacyl lignin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guaiacyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "G-lignin metabolic process" EXACT [GOC:mengo_curators] +synonym: "guaiacyl lignin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009808 ! lignin metabolic process +created_by: tt +creation_date: 2012-06-29T02:46:39Z + +[Term] +id: GO:1901062 +name: guaiacyl lignin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "G-lignin catabolic process" EXACT [GOC:mengo_curators] +synonym: "guaiacyl lignin breakdown" EXACT [GOC:TermGenie] +synonym: "guaiacyl lignin catabolism" EXACT [GOC:TermGenie] +synonym: "guaiacyl lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0046274 ! lignin catabolic process +is_a: GO:1901061 ! guaiacyl lignin metabolic process +created_by: tt +creation_date: 2012-06-29T02:47:03Z + +[Term] +id: GO:1901063 +name: guaiacyl lignin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guaiacyl lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "G-lignin biosynthetic process" EXACT [GOC:mengo_curators] +synonym: "guaiacyl lignin anabolism" EXACT [GOC:TermGenie] +synonym: "guaiacyl lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "guaiacyl lignin formation" EXACT [GOC:TermGenie] +synonym: "guaiacyl lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009809 ! lignin biosynthetic process +is_a: GO:1901061 ! guaiacyl lignin metabolic process +created_by: tt +creation_date: 2012-06-29T03:29:53Z + +[Term] +id: GO:1901064 +name: syringal lignin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving syringal lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "S-lignin metabolic process" EXACT [GOC:mengo_curators] +synonym: "syringal lignin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009808 ! lignin metabolic process +created_by: tt +creation_date: 2012-06-29T03:48:11Z + +[Term] +id: GO:1901065 +name: syringal lignin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of syringal lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "S-lignin catabolic process" EXACT [GOC:mengo_curators] +synonym: "syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "syringal lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0046274 ! lignin catabolic process +is_a: GO:1901064 ! syringal lignin metabolic process +created_by: tt +creation_date: 2012-06-29T03:48:33Z + +[Term] +id: GO:1901066 +name: syringal lignin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of syringal lignin." [GOC:mengo_curators, GOC:TermGenie] +synonym: "S-lignin biosynthetic process" EXACT [GOC:mengo_curators] +synonym: "syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "syringal lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009809 ! lignin biosynthetic process +is_a: GO:1901064 ! syringal lignin metabolic process +created_by: tt +creation_date: 2012-06-29T03:48:41Z + +[Term] +id: GO:1901067 +name: ferulate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ferulate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "ferulate degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0033494 ! ferulate metabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: tt +creation_date: 2012-06-29T08:06:37Z + +[Term] +id: GO:1901068 +name: guanosine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving guanosine-containing compounds (guanosines)." [GOC:TermGenie] +synonym: "guanosine-containing compound metabolism" EXACT [GOC:bf] +synonym: "guanosines metabolic process" EXACT [CHEBI:24458] +synonym: "guanosines metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046128 ! purine ribonucleoside metabolic process +created_by: bf +creation_date: 2012-07-02T01:51:37Z + +[Term] +id: GO:1901069 +name: guanosine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines)." [GOC:TermGenie] +synonym: "guanosine-containing compound breakdown" EXACT [GOC:bf] +synonym: "guanosine-containing compound catabolism" EXACT [GOC:bf] +synonym: "guanosine-containing compound degradation" EXACT [GOC:bf] +synonym: "guanosines breakdown" EXACT [GOC:TermGenie] +synonym: "guanosines catabolic process" EXACT [CHEBI:24458] +synonym: "guanosines catabolism" EXACT [GOC:TermGenie] +synonym: "guanosines degradation" EXACT [GOC:TermGenie] +is_a: GO:0046130 ! purine ribonucleoside catabolic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process +created_by: bf +creation_date: 2012-07-02T01:52:00Z + +[Term] +id: GO:1901070 +name: guanosine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines)." [GOC:TermGenie] +synonym: "guanosine-containing compound anabolism" EXACT [GOC:bf] +synonym: "guanosine-containing compound biosynthesis" EXACT [GOC:bf] +synonym: "guanosine-containing compound formation" EXACT [GOC:bf] +synonym: "guanosine-containing compound synthesis" EXACT [GOC:bf] +synonym: "guanosines anabolism" EXACT [GOC:TermGenie] +synonym: "guanosines biosynthesis" EXACT [GOC:TermGenie] +synonym: "guanosines biosynthetic process" EXACT [CHEBI:24458] +synonym: "guanosines formation" EXACT [GOC:TermGenie] +synonym: "guanosines synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process +is_a: GO:1901068 ! guanosine-containing compound metabolic process +created_by: bf +creation_date: 2012-07-02T01:52:09Z + +[Term] +id: GO:1901071 +name: glucosamine-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] +synonym: "glucosamine-containing compound metabolism" EXACT [GOC:bf] +synonym: "glucosamines metabolic process" EXACT [CHEBI:24271] +synonym: "glucosamines metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006040 ! amino sugar metabolic process +created_by: bf +creation_date: 2012-07-02T03:18:04Z + +[Term] +id: GO:1901072 +name: glucosamine-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] +synonym: "glucosamine-containing compound breakdown" EXACT [GOC:bf] +synonym: "glucosamine-containing compound catabolism" EXACT [GOC:bf] +synonym: "glucosamine-containing compound degradation" EXACT [GOC:bf] +synonym: "glucosamines breakdown" EXACT [GOC:TermGenie] +synonym: "glucosamines catabolic process" EXACT [CHEBI:24271] +synonym: "glucosamines catabolism" EXACT [GOC:TermGenie] +synonym: "glucosamines degradation" EXACT [GOC:TermGenie] +is_a: GO:0046348 ! amino sugar catabolic process +is_a: GO:1901071 ! glucosamine-containing compound metabolic process +created_by: bf +creation_date: 2012-07-02T03:18:25Z + +[Term] +id: GO:1901073 +name: glucosamine-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie] +synonym: "glucosamine-containing compound anabolism" EXACT [GOC:bf] +synonym: "glucosamine-containing compound biosynthesis" EXACT [GOC:bf] +synonym: "glucosamine-containing compound formation" EXACT [GOC:bf] +synonym: "glucosamine-containing compound synthesis" EXACT [GOC:bf] +synonym: "glucosamines anabolism" EXACT [GOC:TermGenie] +synonym: "glucosamines biosynthesis" EXACT [GOC:TermGenie] +synonym: "glucosamines biosynthetic process" EXACT [CHEBI:24271] +synonym: "glucosamines formation" EXACT [GOC:TermGenie] +synonym: "glucosamines synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046349 ! amino sugar biosynthetic process +is_a: GO:1901071 ! glucosamine-containing compound metabolic process +created_by: bf +creation_date: 2012-07-02T03:18:33Z + +[Term] +id: GO:1901074 +name: regulation of engulfment of apoptotic cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell." [GO:kmv, GOC:TermGenie, PMID:19402756] +synonym: "regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +is_a: GO:0060099 ! regulation of phagocytosis, engulfment +is_a: GO:2000425 ! regulation of apoptotic cell clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043652 ! engulfment of apoptotic cell +relationship: regulates GO:0043652 ! engulfment of apoptotic cell +created_by: kmv +creation_date: 2012-07-02T07:32:21Z + +[Term] +id: GO:1901075 +name: negative regulation of engulfment of apoptotic cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell." [GO:kmv, GOC:TermGenie, PMID:19402756] +synonym: "down regulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "down regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "down regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "down-regulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "down-regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "downregulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "downregulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "downregulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "inhibition of engulfment of apoptotic cell" NARROW [GOC:TermGenie] +synonym: "inhibition of engulfment of apoptotic cell corpse" NARROW [GOC:TermGenie] +synonym: "inhibition of engulfment of cell corpse" NARROW [GOC:TermGenie] +synonym: "negative regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "negative regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +is_a: GO:0060101 ! negative regulation of phagocytosis, engulfment +is_a: GO:1901074 ! regulation of engulfment of apoptotic cell +is_a: GO:2000426 ! negative regulation of apoptotic cell clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043652 ! engulfment of apoptotic cell +relationship: negatively_regulates GO:0043652 ! engulfment of apoptotic cell +created_by: kmv +creation_date: 2012-07-02T07:32:43Z + +[Term] +id: GO:1901076 +name: positive regulation of engulfment of apoptotic cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell." [GO:kmv, GOC:TermGenie, PMID:19402756] +synonym: "activation of engulfment of apoptotic cell" NARROW [GOC:TermGenie] +synonym: "activation of engulfment of apoptotic cell corpse" NARROW [GOC:TermGenie] +synonym: "activation of engulfment of cell corpse" NARROW [GOC:TermGenie] +synonym: "positive regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "positive regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "up regulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "up regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "up regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "up-regulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "up-regulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +synonym: "upregulation of engulfment of apoptotic cell" EXACT [GOC:TermGenie] +synonym: "upregulation of engulfment of apoptotic cell corpse" EXACT [GOC:TermGenie] +synonym: "upregulation of engulfment of cell corpse" EXACT [GOC:TermGenie] +is_a: GO:0060100 ! positive regulation of phagocytosis, engulfment +is_a: GO:1901074 ! regulation of engulfment of apoptotic cell +is_a: GO:2000427 ! positive regulation of apoptotic cell clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043652 ! engulfment of apoptotic cell +relationship: positively_regulates GO:0043652 ! engulfment of apoptotic cell +created_by: kmv +creation_date: 2012-07-02T07:32:51Z + +[Term] +id: GO:1901077 +name: regulation of relaxation of muscle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of relaxation of muscle." [GOC:TermGenie] +is_a: GO:0090257 ! regulation of muscle system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090075 ! relaxation of muscle +relationship: regulates GO:0090075 ! relaxation of muscle +created_by: jl +creation_date: 2012-07-04T10:44:30Z + +[Term] +id: GO:1901078 +name: negative regulation of relaxation of muscle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle." [GOC:TermGenie] +synonym: "down regulation of relaxation of muscle" EXACT [GOC:TermGenie] +synonym: "down-regulation of relaxation of muscle" EXACT [GOC:TermGenie] +synonym: "downregulation of relaxation of muscle" EXACT [GOC:TermGenie] +synonym: "inhibition of relaxation of muscle" NARROW [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901077 ! regulation of relaxation of muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090075 ! relaxation of muscle +relationship: negatively_regulates GO:0090075 ! relaxation of muscle +created_by: jl +creation_date: 2012-07-04T10:44:54Z + +[Term] +id: GO:1901079 +name: positive regulation of relaxation of muscle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of relaxation of muscle." [GOC:TermGenie] +synonym: "activation of relaxation of muscle" NARROW [GOC:TermGenie] +synonym: "up regulation of relaxation of muscle" EXACT [GOC:TermGenie] +synonym: "up-regulation of relaxation of muscle" EXACT [GOC:TermGenie] +synonym: "upregulation of relaxation of muscle" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901077 ! regulation of relaxation of muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090075 ! relaxation of muscle +relationship: positively_regulates GO:0090075 ! relaxation of muscle +created_by: jl +creation_date: 2012-07-04T10:45:02Z + +[Term] +id: GO:1901080 +name: regulation of relaxation of smooth muscle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of relaxation of smooth muscle." [GOC:TermGenie] +synonym: "regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +is_a: GO:1901077 ! regulation of relaxation of muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044557 ! relaxation of smooth muscle +relationship: regulates GO:0044557 ! relaxation of smooth muscle +created_by: jl +creation_date: 2012-07-04T10:45:09Z + +[Term] +id: GO:1901081 +name: negative regulation of relaxation of smooth muscle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle." [GOC:TermGenie] +synonym: "down regulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "down regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "down-regulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "down-regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "downregulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "downregulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "inhibition of relaxation of smooth muscle" NARROW [GOC:TermGenie] +synonym: "inhibition of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "negative regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +is_a: GO:1901078 ! negative regulation of relaxation of muscle +is_a: GO:1901080 ! regulation of relaxation of smooth muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044557 ! relaxation of smooth muscle +relationship: negatively_regulates GO:0044557 ! relaxation of smooth muscle +created_by: jl +creation_date: 2012-07-04T10:45:31Z + +[Term] +id: GO:1901082 +name: positive regulation of relaxation of smooth muscle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle." [GOC:TermGenie] +synonym: "activation of relaxation of smooth muscle" NARROW [GOC:TermGenie] +synonym: "activation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "positive regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "up regulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "up regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "up-regulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +synonym: "upregulation of relaxation of smooth muscle" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle relaxation" EXACT [GOC:TermGenie] +is_a: GO:1901079 ! positive regulation of relaxation of muscle +is_a: GO:1901080 ! regulation of relaxation of smooth muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044557 ! relaxation of smooth muscle +relationship: positively_regulates GO:0044557 ! relaxation of smooth muscle +created_by: jl +creation_date: 2012-07-04T10:45:39Z + +[Term] +id: GO:1901083 +name: pyrrolizidine alkaloid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pyrrolizidine alkaloid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00329] +synonym: "pyrrolizidine alkaloid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009820 ! alkaloid metabolic process +created_by: yaf +creation_date: 2012-07-05T10:27:56Z + +[Term] +id: GO:1901084 +name: pyrrolizidine alkaloid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00329] +synonym: "pyrrolizidine alkaloid breakdown" EXACT [GOC:TermGenie] +synonym: "pyrrolizidine alkaloid catabolism" EXACT [GOC:TermGenie] +synonym: "pyrrolizidine alkaloid degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:1901083 ! pyrrolizidine alkaloid metabolic process +created_by: yaf +creation_date: 2012-07-05T10:28:20Z + +[Term] +id: GO:1901085 +name: pyrrolizidine alkaloid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00329] +synonym: "pyrrolizidine alkaloid anabolism" EXACT [GOC:TermGenie] +synonym: "pyrrolizidine alkaloid biosynthesis" EXACT [GOC:TermGenie] +synonym: "pyrrolizidine alkaloid formation" EXACT [GOC:TermGenie] +synonym: "pyrrolizidine alkaloid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:1901083 ! pyrrolizidine alkaloid metabolic process +created_by: yaf +creation_date: 2012-07-05T10:28:28Z + +[Term] +id: GO:1901086 +name: benzylpenicillin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzylpenicillin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00149] +synonym: "benzylpenicillin metabolism" EXACT [GOC:TermGenie] +synonym: "penicillin G metabolism" EXACT [] +is_a: GO:0042316 ! penicillin metabolic process +created_by: yaf +creation_date: 2012-07-05T10:28:33Z + +[Term] +id: GO:1901087 +name: benzylpenicillin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzylpenicillin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00149] +synonym: "benzylpenicillin breakdown" EXACT [GOC:TermGenie] +synonym: "benzylpenicillin catabolism" EXACT [GOC:TermGenie] +synonym: "benzylpenicillin degradation" EXACT [GOC:TermGenie] +synonym: "penicillin G breakdown" EXACT [] +synonym: "penicillin G catabolic process" EXACT [] +synonym: "penicillin G catabolism" EXACT [] +synonym: "penicillin G degradation" EXACT [] +is_a: GO:0042317 ! penicillin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901086 ! benzylpenicillin metabolic process +created_by: yaf +creation_date: 2012-07-05T10:28:59Z + +[Term] +id: GO:1901088 +name: benzylpenicillin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of benzylpenicillin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00149] +synonym: "benzylpenicillin anabolism" EXACT [GOC:TermGenie] +synonym: "benzylpenicillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "benzylpenicillin formation" EXACT [GOC:TermGenie] +synonym: "benzylpenicillin synthesis" EXACT [GOC:TermGenie] +synonym: "penicillin G anabolism" EXACT [GOC:yaf] +synonym: "penicillin G biosynthesis" EXACT [GOC:yaf] +synonym: "penicillin G formation" EXACT [GOC:yaf] +synonym: "penicillin G synthesis" EXACT [GOC:yaf] +is_a: GO:0042318 ! penicillin biosynthetic process +is_a: GO:1901086 ! benzylpenicillin metabolic process +created_by: yaf +creation_date: 2012-07-05T10:29:07Z + +[Term] +id: GO:1901089 +name: acetate ester metabolic process involved in fermentation +namespace: biological_process +def: "Any acetate ester metabolic process that is involved in fermentation." [GOC:sgd_curators, GOC:TermGenie] +synonym: "acetate ester metabolic process during fermentation" EXACT [GOC:sgd_curators] +is_a: GO:1900619 ! acetate ester metabolic process +intersection_of: GO:1900619 ! acetate ester metabolic process +intersection_of: part_of GO:0006113 ! fermentation +relationship: part_of GO:0006113 ! fermentation +created_by: rb +creation_date: 2012-07-05T11:47:17Z + +[Term] +id: GO:1901090 +name: regulation of protein tetramerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein tetramerization." [GOC:pm, GOC:TermGenie] +synonym: "regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of protein tetramer formation" EXACT [GOC:TermGenie] +is_a: GO:0032459 ! regulation of protein oligomerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051262 ! protein tetramerization +relationship: regulates GO:0051262 ! protein tetramerization +created_by: pm +creation_date: 2012-07-06T12:51:00Z + +[Term] +id: GO:1901091 +name: negative regulation of protein tetramerization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization." [GOC:pm, GOC:TermGenie] +synonym: "down regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein tetramerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tetramerization" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tetramerization" EXACT [GOC:TermGenie] +synonym: "inhibition of protein tetramer assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of protein tetramer biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of protein tetramer biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of protein tetramer formation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein tetramerization" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein tetramer formation" EXACT [GOC:TermGenie] +is_a: GO:0032460 ! negative regulation of protein oligomerization +is_a: GO:1901090 ! regulation of protein tetramerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051262 ! protein tetramerization +relationship: negatively_regulates GO:0051262 ! protein tetramerization +created_by: pm +creation_date: 2012-07-06T12:51:24Z + +[Term] +id: GO:1901092 +name: positive regulation of protein tetramerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein tetramerization." [GOC:pm, GOC:TermGenie] +synonym: "activation of protein tetramer assembly" NARROW [GOC:TermGenie] +synonym: "activation of protein tetramer biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of protein tetramer biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of protein tetramer formation" NARROW [GOC:TermGenie] +synonym: "activation of protein tetramerization" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tetramerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tetramerization" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tetramer assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tetramer formation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tetramerization" EXACT [GOC:TermGenie] +is_a: GO:0032461 ! positive regulation of protein oligomerization +is_a: GO:1901090 ! regulation of protein tetramerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051262 ! protein tetramerization +relationship: positively_regulates GO:0051262 ! protein tetramerization +created_by: pm +creation_date: 2012-07-06T12:51:32Z + +[Term] +id: GO:1901093 +name: regulation of protein homotetramerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein homotetramerization." [GOC:pm, GOC:TermGenie] +synonym: "regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +is_a: GO:0032462 ! regulation of protein homooligomerization +is_a: GO:1901090 ! regulation of protein tetramerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051289 ! protein homotetramerization +relationship: regulates GO:0051289 ! protein homotetramerization +created_by: pm +creation_date: 2012-07-06T12:57:33Z + +[Term] +id: GO:1901094 +name: negative regulation of protein homotetramerization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization." [GOC:pm, GOC:TermGenie] +synonym: "down regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein homotetramerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein homotetramerization" EXACT [GOC:TermGenie] +synonym: "downregulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein homotetramerization" EXACT [GOC:TermGenie] +synonym: "inhibition of protein homotetramer assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of protein homotetramer biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of protein homotetramer biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of protein homotetramer formation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein homotetramerization" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +is_a: GO:0032463 ! negative regulation of protein homooligomerization +is_a: GO:1901091 ! negative regulation of protein tetramerization +is_a: GO:1901093 ! regulation of protein homotetramerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051289 ! protein homotetramerization +relationship: negatively_regulates GO:0051289 ! protein homotetramerization +created_by: pm +creation_date: 2012-07-06T12:57:58Z + +[Term] +id: GO:1901095 +name: positive regulation of protein homotetramerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein homotetramerization." [GOC:pm, GOC:TermGenie] +synonym: "activation of protein homotetramer assembly" NARROW [GOC:TermGenie] +synonym: "activation of protein homotetramer biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of protein homotetramer biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of protein homotetramer formation" NARROW [GOC:TermGenie] +synonym: "activation of protein homotetramerization" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein homotetramerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein homotetramerization" EXACT [GOC:TermGenie] +synonym: "upregulation of protein homotetramer assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of protein homotetramer biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of protein homotetramer biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of protein homotetramer formation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein homotetramerization" EXACT [GOC:TermGenie] +is_a: GO:0032464 ! positive regulation of protein homooligomerization +is_a: GO:1901092 ! positive regulation of protein tetramerization +is_a: GO:1901093 ! regulation of protein homotetramerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051289 ! protein homotetramerization +relationship: positively_regulates GO:0051289 ! protein homotetramerization +created_by: pm +creation_date: 2012-07-06T12:58:06Z + +[Term] +id: GO:1901096 +name: regulation of autophagosome maturation +namespace: biological_process +alt_id: GO:1902452 +def: "Any process that modulates the frequency, rate or extent of autophagosome maturation." [GOC:autophagy, GOC:TermGenie, PMID:10436019, PMID:21383079] +synonym: "regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "regulation of autophagic vacuole fusion" EXACT [GOC:autophagy] +synonym: "regulation of autophagosome fusion" EXACT [] +synonym: "regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +is_a: GO:0016241 ! regulation of macroautophagy +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097352 ! autophagosome maturation +relationship: regulates GO:0097352 ! autophagosome maturation +created_by: lb +creation_date: 2012-07-10T07:22:01Z + +[Term] +id: GO:1901097 +name: negative regulation of autophagosome maturation +namespace: biological_process +alt_id: GO:1902453 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation." [GOC:autophagy, GOC:TermGenie, PMID:10436019, PMID:21383079] +synonym: "down regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "down regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "down regulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "down regulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "down regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "down regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "down-regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "down-regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "downregulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "downregulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "downregulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "inhibition of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "inhibition of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagic vacuole fusion" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagic vacuole maturation" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "negative regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of autophagic vacuole fusion" EXACT [GOC:autophagy] +synonym: "negative regulation of autophagosome fusion" EXACT [] +synonym: "negative regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "negative regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +is_a: GO:1901096 ! regulation of autophagosome maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097352 ! autophagosome maturation +relationship: negatively_regulates GO:0097352 ! autophagosome maturation +created_by: lb +creation_date: 2012-07-10T07:22:26Z + +[Term] +id: GO:1901098 +name: positive regulation of autophagosome maturation +namespace: biological_process +alt_id: GO:1902454 +def: "Any process that activates or increases the frequency, rate or extent of autophagosome maturation." [GOC:autophagy, GOC:TermGenie, PMID:10436019, PMID:21383079] +synonym: "activation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "activation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "activation of autophagic vacuole fusion" NARROW [GOC:TermGenie] +synonym: "activation of autophagic vacuole maturation" NARROW [GOC:TermGenie] +synonym: "activation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "activation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "positive regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of autophagic vacuole fusion" EXACT [GOC:autophagy] +synonym: "positive regulation of autophagosome fusion" EXACT [] +synonym: "positive regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "positive regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "up regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "up regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "up regulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "up regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "up regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "up-regulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "up-regulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +synonym: "upregulation of amphisome-lysosome fusion" NARROW [GOC:TermGenie] +synonym: "upregulation of autolysosome formation" NARROW [GOC:TermGenie] +synonym: "upregulation of autophagic vacuole fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of autophagic vacuole maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of autophagosome maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of fusion of autophagosome with lysosome" NARROW [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly +is_a: GO:1901096 ! regulation of autophagosome maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097352 ! autophagosome maturation +relationship: positively_regulates GO:0097352 ! autophagosome maturation +created_by: lb +creation_date: 2012-07-10T07:22:34Z + +[Term] +id: GO:1901099 +name: negative regulation of signal transduction in absence of ligand +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand." [GOC:TermGenie] +synonym: "down regulation of basal signaling" NARROW [GOC:TermGenie] +synonym: "down regulation of non-classical signal transduction" BROAD [GOC:TermGenie] +synonym: "down regulation of signal transduction in absence of agonist" EXACT [GOC:TermGenie] +synonym: "down regulation of signal transduction in absence of ligand" EXACT [GOC:TermGenie] +synonym: "down-regulation of basal signaling" NARROW [GOC:TermGenie] +synonym: "down-regulation of non-classical signal transduction" BROAD [GOC:TermGenie] +synonym: "down-regulation of signal transduction in absence of agonist" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction in absence of ligand" EXACT [GOC:TermGenie] +synonym: "downregulation of basal signaling" NARROW [GOC:TermGenie] +synonym: "downregulation of non-classical signal transduction" BROAD [GOC:TermGenie] +synonym: "downregulation of signal transduction in absence of agonist" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction in absence of ligand" EXACT [GOC:TermGenie] +synonym: "inhibition of signal transduction in absence of ligand" NARROW [GOC:TermGenie] +synonym: "negative regulation of non-classical signal transduction" BROAD [GOC:TermGenie] +synonym: "negative regulation of signal transduction in absence of agonist" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038034 ! signal transduction in absence of ligand +relationship: negatively_regulates GO:0038034 ! signal transduction in absence of ligand +created_by: al +creation_date: 2012-07-10T10:31:08Z + +[Term] +id: GO:1901101 +name: gramicidin S metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gramicidin S." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00102] +synonym: "gramicidin S metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006518 ! peptide metabolic process +created_by: yaf +creation_date: 2012-07-11T02:30:26Z + +[Term] +id: GO:1901102 +name: gramicidin S catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gramicidin S." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00102] +synonym: "gramicidin S breakdown" EXACT [GOC:TermGenie] +synonym: "gramicidin S catabolism" EXACT [GOC:TermGenie] +synonym: "gramicidin S degradation" EXACT [GOC:TermGenie] +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:1901101 ! gramicidin S metabolic process +created_by: yaf +creation_date: 2012-07-11T02:30:52Z + +[Term] +id: GO:1901103 +name: gramicidin S biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gramicidin S." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00102] +synonym: "gramicidin S anabolism" EXACT [GOC:TermGenie] +synonym: "gramicidin S biosynthesis" EXACT [GOC:TermGenie] +synonym: "gramicidin S formation" EXACT [GOC:TermGenie] +synonym: "gramicidin S synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:1901101 ! gramicidin S metabolic process +created_by: yaf +creation_date: 2012-07-11T02:31:00Z + +[Term] +id: GO:1901104 +name: tetracenomycin C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tetracenomycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00174] +synonym: "tetracenomycin C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: yaf +creation_date: 2012-07-11T02:50:32Z + +[Term] +id: GO:1901105 +name: tetracenomycin C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tetracenomycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00174] +synonym: "tetracenomycin C breakdown" EXACT [GOC:TermGenie] +synonym: "tetracenomycin C catabolism" EXACT [GOC:TermGenie] +synonym: "tetracenomycin C degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1901104 ! tetracenomycin C metabolic process +created_by: yaf +creation_date: 2012-07-11T02:50:54Z + +[Term] +id: GO:1901106 +name: tetracenomycin C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tetracenomycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00174] +synonym: "tetracenomycin C anabolism" EXACT [GOC:TermGenie] +synonym: "tetracenomycin C biosynthesis" EXACT [GOC:TermGenie] +synonym: "tetracenomycin C formation" EXACT [GOC:TermGenie] +synonym: "tetracenomycin C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1901104 ! tetracenomycin C metabolic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process +created_by: yaf +creation_date: 2012-07-11T02:51:03Z + +[Term] +id: GO:1901107 +name: granaticin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving granaticin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00175] +synonym: "granaticin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: yaf +creation_date: 2012-07-11T02:51:08Z + +[Term] +id: GO:1901108 +name: granaticin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of granaticin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00175] +synonym: "granaticin breakdown" EXACT [GOC:TermGenie] +synonym: "granaticin catabolism" EXACT [GOC:TermGenie] +synonym: "granaticin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901107 ! granaticin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: yaf +creation_date: 2012-07-11T02:51:33Z + +[Term] +id: GO:1901109 +name: granaticin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of granaticin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00175] +synonym: "granaticin anabolism" EXACT [GOC:TermGenie] +synonym: "granaticin biosynthesis" EXACT [GOC:TermGenie] +synonym: "granaticin formation" EXACT [GOC:TermGenie] +synonym: "granaticin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:1901107 ! granaticin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: yaf +creation_date: 2012-07-11T02:51:40Z + +[Term] +id: GO:1901110 +name: actinorhodin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving actinorhodin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00173] +synonym: "actinorhodin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: yaf +creation_date: 2012-07-11T03:05:37Z + +[Term] +id: GO:1901111 +name: actinorhodin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of actinorhodin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00173] +synonym: "actinorhodin breakdown" EXACT [GOC:TermGenie] +synonym: "actinorhodin catabolism" EXACT [GOC:TermGenie] +synonym: "actinorhodin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901110 ! actinorhodin metabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: yaf +creation_date: 2012-07-11T03:06:00Z + +[Term] +id: GO:1901112 +name: actinorhodin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of actinorhodin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00173] +synonym: "actinorhodin anabolism" EXACT [GOC:TermGenie] +synonym: "actinorhodin biosynthesis" EXACT [GOC:TermGenie] +synonym: "actinorhodin formation" EXACT [GOC:TermGenie] +synonym: "actinorhodin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901110 ! actinorhodin metabolic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: yaf +creation_date: 2012-07-11T03:06:08Z + +[Term] +id: GO:1901113 +name: erythromycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving erythromycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00240] +synonym: "erythromycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0033067 ! macrolide metabolic process +created_by: yaf +creation_date: 2012-07-11T03:06:13Z + +[Term] +id: GO:1901114 +name: erythromycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of erythromycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00240] +synonym: "erythromycin breakdown" EXACT [GOC:TermGenie] +synonym: "erythromycin catabolism" EXACT [GOC:TermGenie] +synonym: "erythromycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:1901113 ! erythromycin metabolic process +is_a: GO:1901335 ! lactone catabolic process +created_by: yaf +creation_date: 2012-07-11T03:06:38Z + +[Term] +id: GO:1901115 +name: erythromycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of erythromycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00240] +synonym: "erythromycin anabolism" EXACT [GOC:TermGenie] +synonym: "erythromycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "erythromycin formation" EXACT [GOC:TermGenie] +synonym: "erythromycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0033068 ! macrolide biosynthetic process +is_a: GO:1901113 ! erythromycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:06:46Z + +[Term] +id: GO:1901116 +name: cephamycin C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cephamycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00183] +synonym: "cephamycin C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-11T03:06:51Z + +[Term] +id: GO:1901117 +name: cephamycin C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cephamycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00183] +synonym: "cephamycin C breakdown" EXACT [GOC:TermGenie] +synonym: "cephamycin C catabolism" EXACT [GOC:TermGenie] +synonym: "cephamycin C degradation" EXACT [GOC:TermGenie] +is_a: GO:0030655 ! beta-lactam antibiotic catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901116 ! cephamycin C metabolic process +created_by: yaf +creation_date: 2012-07-11T03:07:13Z + +[Term] +id: GO:1901118 +name: cephamycin C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cephamycin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00183] +synonym: "cephamycin C anabolism" EXACT [GOC:TermGenie] +synonym: "cephamycin C biosynthesis" EXACT [GOC:TermGenie] +synonym: "cephamycin C formation" EXACT [GOC:TermGenie] +synonym: "cephamycin C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030654 ! beta-lactam antibiotic biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901116 ! cephamycin C metabolic process +created_by: yaf +creation_date: 2012-07-11T03:07:21Z + +[Term] +id: GO:1901119 +name: tobramycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tobramycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00971] +synonym: "tobramycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0019751 ! polyol metabolic process +created_by: yaf +creation_date: 2012-07-11T03:15:19Z + +[Term] +id: GO:1901120 +name: tobramycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tobramycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00971] +synonym: "tobramycin breakdown" EXACT [GOC:TermGenie] +synonym: "tobramycin catabolism" EXACT [GOC:TermGenie] +synonym: "tobramycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:1901119 ! tobramycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:15:43Z + +[Term] +id: GO:1901121 +name: tobramycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tobramycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00971] +synonym: "tobramycin anabolism" EXACT [GOC:TermGenie] +synonym: "tobramycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "tobramycin formation" EXACT [GOC:TermGenie] +synonym: "tobramycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901119 ! tobramycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:15:51Z + +[Term] +id: GO:1901122 +name: bacitracin A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bacitracin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00179] +synonym: "bacitracin A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-11T03:15:56Z + +[Term] +id: GO:1901123 +name: bacitracin A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of bacitracin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00179] +synonym: "bacitracin A breakdown" EXACT [GOC:TermGenie] +synonym: "bacitracin A catabolism" EXACT [GOC:TermGenie] +synonym: "bacitracin A degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:1901122 ! bacitracin A metabolic process +created_by: yaf +creation_date: 2012-07-11T03:16:20Z + +[Term] +id: GO:1901124 +name: bacitracin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of bacitracin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00179] +synonym: "bacitracin A anabolism" EXACT [GOC:TermGenie] +synonym: "bacitracin A biosynthesis" EXACT [GOC:TermGenie] +synonym: "bacitracin A formation" EXACT [GOC:TermGenie] +synonym: "bacitracin A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:1901122 ! bacitracin A metabolic process +created_by: yaf +creation_date: 2012-07-11T03:16:27Z + +[Term] +id: GO:1901125 +name: candicidin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving candicidin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00101] +synonym: "candicidin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: yaf +creation_date: 2012-07-11T03:16:32Z + +[Term] +id: GO:1901126 +name: candicidin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of candicidin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00101] +synonym: "candicidin breakdown" EXACT [GOC:TermGenie] +synonym: "candicidin catabolism" EXACT [GOC:TermGenie] +synonym: "candicidin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901125 ! candicidin metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: yaf +creation_date: 2012-07-11T03:16:54Z + +[Term] +id: GO:1901127 +name: candicidin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of candicidin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00101] +synonym: "candicidin anabolism" EXACT [GOC:TermGenie] +synonym: "candicidin biosynthesis" EXACT [GOC:TermGenie] +synonym: "candicidin formation" EXACT [GOC:TermGenie] +synonym: "candicidin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:1901125 ! candicidin metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: yaf +creation_date: 2012-07-11T03:17:02Z + +[Term] +id: GO:1901128 +name: gentamycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving gentamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00967] +synonym: "gentamycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-11T03:26:25Z + +[Term] +id: GO:1901129 +name: gentamycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of gentamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00967] +synonym: "gentamycin breakdown" EXACT [GOC:TermGenie] +synonym: "gentamycin catabolism" EXACT [GOC:TermGenie] +synonym: "gentamycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0030649 ! aminoglycoside antibiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901128 ! gentamycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:26:51Z + +[Term] +id: GO:1901130 +name: gentamycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of gentamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00967] +synonym: "gentamycin anabolism" EXACT [GOC:TermGenie] +synonym: "gentamycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "gentamycin formation" EXACT [GOC:TermGenie] +synonym: "gentamycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901128 ! gentamycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:26:59Z + +[Term] +id: GO:1901131 +name: kanamycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving kanamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00965] +synonym: "kanamycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-11T03:27:04Z + +[Term] +id: GO:1901132 +name: kanamycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of kanamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00965] +synonym: "kanamycin breakdown" EXACT [GOC:TermGenie] +synonym: "kanamycin catabolism" EXACT [GOC:TermGenie] +synonym: "kanamycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0030649 ! aminoglycoside antibiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901131 ! kanamycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:27:24Z + +[Term] +id: GO:1901133 +name: kanamycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of kanamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00965] +synonym: "kanamycin anabolism" EXACT [GOC:TermGenie] +synonym: "kanamycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "kanamycin formation" EXACT [GOC:TermGenie] +synonym: "kanamycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901131 ! kanamycin metabolic process +created_by: yaf +creation_date: 2012-07-11T03:27:32Z + +[Term] +id: GO:1901134 +name: negative regulation of coflocculation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of coflocculation, non-sexual aggregation between single-celled organisms of different species." [GOC:TermGenie, PMID:11472912] +synonym: "down regulation of coflocculation via lectin-mannose interaction" NARROW [GOC:TermGenie] +synonym: "down regulation of coflocculation via protein-carbohydrate interaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of coflocculation via lectin-mannose interaction" NARROW [GOC:TermGenie] +synonym: "down-regulation of coflocculation via protein-carbohydrate interaction" EXACT [GOC:TermGenie] +synonym: "downregulation of coflocculation via lectin-mannose interaction" NARROW [GOC:TermGenie] +synonym: "downregulation of coflocculation via protein-carbohydrate interaction" EXACT [GOC:TermGenie] +synonym: "inhibition of coflocculation via lectin-mannose interaction" NARROW [GOC:TermGenie] +synonym: "inhibition of coflocculation via protein-carbohydrate interaction" NARROW [GOC:TermGenie] +synonym: "negative regulation of coflocculation via lectin-mannose interaction" NARROW [GOC:TermGenie] +synonym: "negative regulation of coflocculation via protein-carbohydrate interaction" NARROW [] +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036281 ! coflocculation +relationship: negatively_regulates GO:0036281 ! coflocculation +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18785 xsd:anyURI +created_by: al +creation_date: 2012-07-12T07:17:11Z + +[Term] +id: GO:1901135 +name: carbohydrate derivative metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie] +subset: goslim_agr +subset: goslim_mouse +synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: bf +creation_date: 2012-07-12T04:05:09Z + +[Term] +id: GO:1901136 +name: carbohydrate derivative catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie] +synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] +synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] +synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] +is_a: GO:1901135 ! carbohydrate derivative metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: bf +creation_date: 2012-07-12T04:05:31Z + +[Term] +id: GO:1901137 +name: carbohydrate derivative biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie] +synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] +synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] +synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] +synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901135 ! carbohydrate derivative metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: bf +creation_date: 2012-07-12T04:05:39Z + +[Term] +id: GO:1901140 +name: p-coumaryl alcohol transport +namespace: biological_process +def: "The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] +synonym: "4-hydroxycinnamyl alcohol transport" EXACT [] +is_a: GO:0015850 ! organic hydroxy compound transport +created_by: tb +creation_date: 2012-07-12T09:46:16Z + +[Term] +id: GO:1901141 +name: regulation of lignin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lignin biosynthetic process." [GOC:TermGenie] +synonym: "regulation of lignin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of lignin formation" EXACT [GOC:TermGenie] +synonym: "regulation of lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +is_a: GO:2000762 ! regulation of phenylpropanoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009809 ! lignin biosynthetic process +relationship: regulates GO:0009809 ! lignin biosynthetic process +created_by: tb +creation_date: 2012-07-12T09:53:09Z + +[Term] +id: GO:1901142 +name: insulin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie] +synonym: "insulin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019538 ! protein metabolic process +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: pm +creation_date: 2012-07-13T12:32:40Z + +[Term] +id: GO:1901143 +name: insulin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie] +synonym: "insulin breakdown" EXACT [GOC:TermGenie] +synonym: "insulin catabolism" EXACT [GOC:TermGenie] +synonym: "insulin degradation" EXACT [GOC:TermGenie] +is_a: GO:0030163 ! protein catabolic process +is_a: GO:1901142 ! insulin metabolic process +created_by: pm +creation_date: 2012-07-13T12:33:03Z + +[Term] +id: GO:1901144 +name: obsolete insulin biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin." [GOC:TermGenie] +synonym: "insulin anabolism" EXACT [GOC:TermGenie] +synonym: "insulin biosynthesis" EXACT [GOC:TermGenie] +synonym: "insulin biosynthetic process" EXACT [] +synonym: "insulin formation" EXACT [GOC:TermGenie] +synonym: "insulin synthesis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pm +creation_date: 2012-07-13T12:33:10Z + +[Term] +id: GO:1901145 +name: mesenchymal cell apoptotic process involved in nephron morphogenesis +namespace: biological_process +def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +is_a: GO:0097152 ! mesenchymal cell apoptotic process +intersection_of: GO:0097152 ! mesenchymal cell apoptotic process +intersection_of: part_of GO:0072028 ! nephron morphogenesis +relationship: part_of GO:0072028 ! nephron morphogenesis +created_by: pr +creation_date: 2012-07-13T01:43:51Z + +[Term] +id: GO:1901146 +name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis +namespace: biological_process +def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] +is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +intersection_of: GO:0097152 ! mesenchymal cell apoptotic process +intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis +relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis +created_by: pr +creation_date: 2012-07-13T02:40:43Z + +[Term] +id: GO:1901147 +name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis +namespace: biological_process +def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] +is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development +is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis +intersection_of: GO:0097152 ! mesenchymal cell apoptotic process +intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis +relationship: part_of GO:0072273 ! metanephric nephron morphogenesis +created_by: pr +creation_date: 2012-07-13T02:41:12Z + +[Term] +id: GO:1901148 +name: gene expression involved in extracellular matrix organization +namespace: biological_process +def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558] +synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf] +synonym: "extracellular matrix protein production" RELATED [GOC:pg] +is_a: GO:0010467 ! gene expression +intersection_of: GO:0010467 ! gene expression +intersection_of: part_of GO:0030198 ! extracellular matrix organization +relationship: part_of GO:0030198 ! extracellular matrix organization +created_by: bf +creation_date: 2012-07-16T03:29:30Z + +[Term] +id: GO:1901149 +name: salicylic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with salicylic acid." [GOC:TermGenie, PMID:22699612] +synonym: "salicylic acid receptor" NARROW [PMID:22699612] +is_a: GO:0008144 ! drug binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: dhl +creation_date: 2012-07-16T05:26:38Z + +[Term] +id: GO:1901150 +name: vistamycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving vistamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00972] +synonym: "ribostamycin metabolic process" EXACT [GOC:yaf] +synonym: "ribostamycin metabolism" EXACT [GOC:yaf] +synonym: "vistamycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-17T04:26:45Z + +[Term] +id: GO:1901151 +name: vistamycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of vistamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00972] +synonym: "ribostamycin breakdown" EXACT [GOC:yaf] +synonym: "ribostamycin catabolic process" EXACT [GOC:yaf] +synonym: "ribostamycin catabolism" EXACT [GOC:yaf] +synonym: "ribostamycin degradation" EXACT [GOC:yaf] +synonym: "vistamycin breakdown" EXACT [GOC:TermGenie] +synonym: "vistamycin catabolism" EXACT [GOC:TermGenie] +synonym: "vistamycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901150 ! vistamycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:07Z + +[Term] +id: GO:1901152 +name: vistamycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vistamycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00972] +synonym: "ribostamycin anabolism" EXACT [GOC:yaf] +synonym: "ribostamycin biosynthesis" EXACT [GOC:yaf] +synonym: "ribostamycin biosynthetic process" EXACT [GOC:yaf] +synonym: "ribostamycin formation" EXACT [GOC:yaf] +synonym: "ribostamycin synthesis" EXACT [GOC:yaf] +synonym: "vistamycin anabolism" EXACT [GOC:TermGenie] +synonym: "vistamycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "vistamycin formation" EXACT [GOC:TermGenie] +synonym: "vistamycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901150 ! vistamycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:15Z + +[Term] +id: GO:1901153 +name: paromomycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving paromomycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00970] +synonym: "paromomycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:20Z + +[Term] +id: GO:1901154 +name: paromomycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of paromomycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00970] +synonym: "paromomycin breakdown" EXACT [GOC:TermGenie] +synonym: "paromomycin catabolism" EXACT [GOC:TermGenie] +synonym: "paromomycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0030649 ! aminoglycoside antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901153 ! paromomycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:44Z + +[Term] +id: GO:1901155 +name: paromomycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of paromomycin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00970] +synonym: "paromomycin anabolism" EXACT [GOC:TermGenie] +synonym: "paromomycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "paromomycin formation" EXACT [GOC:TermGenie] +synonym: "paromomycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901153 ! paromomycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:51Z + +[Term] +id: GO:1901156 +name: neomycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving neomycin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-7016, UniPathway:UPA00969] +synonym: "neomycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0030647 ! aminoglycoside antibiotic metabolic process +created_by: yaf +creation_date: 2012-07-17T04:27:57Z + +[Term] +id: GO:1901157 +name: neomycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of neomycin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-7016, UniPathway:UPA00969] +synonym: "neomycin breakdown" EXACT [GOC:TermGenie] +synonym: "neomycin catabolism" EXACT [GOC:TermGenie] +synonym: "neomycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0030649 ! aminoglycoside antibiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901156 ! neomycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:28:20Z + +[Term] +id: GO:1901158 +name: neomycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of neomycin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-7016, UniPathway:UPA00969] +synonym: "neomycin anabolism" EXACT [GOC:TermGenie] +synonym: "neomycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "neomycin formation" EXACT [GOC:TermGenie] +synonym: "neomycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901156 ! neomycin metabolic process +created_by: yaf +creation_date: 2012-07-17T04:28:28Z + +[Term] +id: GO:1901159 +name: xylulose 5-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate." [GOC:bf, GOC:TermGenie] +synonym: "xylulose 5-phosphate anabolism" EXACT [GOC:TermGenie] +synonym: "xylulose 5-phosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "xylulose 5-phosphate formation" EXACT [GOC:TermGenie] +synonym: "xylulose 5-phosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051167 ! xylulose 5-phosphate metabolic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +created_by: bf +creation_date: 2012-07-18T04:42:24Z + +[Term] +id: GO:1901160 +name: primary amino compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving primary amino compound." [GOC:TermGenie] +synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: bf +creation_date: 2012-07-18T04:44:39Z + +[Term] +id: GO:1901161 +name: primary amino compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie] +synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] +synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] +synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] +is_a: GO:1901160 ! primary amino compound metabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +created_by: bf +creation_date: 2012-07-18T04:45:06Z + +[Term] +id: GO:1901162 +name: primary amino compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie] +synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] +synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "primary amino compound formation" EXACT [GOC:TermGenie] +synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901160 ! primary amino compound metabolic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: bf +creation_date: 2012-07-18T04:45:14Z + +[Term] +id: GO:1901163 +name: regulation of trophoblast cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061450 ! trophoblast cell migration +relationship: regulates GO:0061450 ! trophoblast cell migration +created_by: vk +creation_date: 2012-07-19T07:53:06Z + +[Term] +id: GO:1901164 +name: negative regulation of trophoblast cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of trophoblast cell migration" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901163 ! regulation of trophoblast cell migration +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061450 ! trophoblast cell migration +relationship: negatively_regulates GO:0061450 ! trophoblast cell migration +created_by: vk +creation_date: 2012-07-19T07:53:28Z + +[Term] +id: GO:1901165 +name: positive regulation of trophoblast cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] +synonym: "activation of trophoblast cell migration" NARROW [GOC:TermGenie] +synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901163 ! regulation of trophoblast cell migration +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061450 ! trophoblast cell migration +relationship: positively_regulates GO:0061450 ! trophoblast cell migration +created_by: vk +creation_date: 2012-07-19T07:53:35Z + +[Term] +id: GO:1901166 +name: neural crest cell migration involved in autonomic nervous system development +namespace: biological_process +def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie] +is_a: GO:0001755 ! neural crest cell migration +intersection_of: GO:0001755 ! neural crest cell migration +intersection_of: part_of GO:0048483 ! autonomic nervous system development +relationship: part_of GO:0048483 ! autonomic nervous system development +created_by: vk +creation_date: 2012-07-19T08:39:56Z + +[Term] +id: GO:1901167 +name: 3-chlorocatechol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-chlorocatechol." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00083] +synonym: "3-chlorocatechol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009712 ! catechol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: yaf +creation_date: 2012-07-19T09:33:16Z + +[Term] +id: GO:1901168 +name: 3-chlorocatechol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00083] +synonym: "3-chlorocatechol breakdown" EXACT [GOC:TermGenie] +synonym: "3-chlorocatechol catabolism" EXACT [GOC:TermGenie] +synonym: "3-chlorocatechol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019614 ! catechol-containing compound catabolic process +is_a: GO:1901167 ! 3-chlorocatechol metabolic process +created_by: yaf +creation_date: 2012-07-19T09:33:38Z + +[Term] +id: GO:1901169 +name: 3-chlorocatechol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-chlorocatechol." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00083] +synonym: "3-chlorocatechol anabolism" EXACT [GOC:TermGenie] +synonym: "3-chlorocatechol biosynthesis" EXACT [GOC:TermGenie] +synonym: "3-chlorocatechol formation" EXACT [GOC:TermGenie] +synonym: "3-chlorocatechol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009713 ! catechol-containing compound biosynthetic process +is_a: GO:1901167 ! 3-chlorocatechol metabolic process +created_by: yaf +creation_date: 2012-07-19T09:33:45Z + +[Term] +id: GO:1901170 +name: naphthalene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of naphthalene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00082] +synonym: "naphthalene breakdown" EXACT [GOC:TermGenie] +synonym: "naphthalene catabolism" EXACT [GOC:TermGenie] +synonym: "naphthalene degradation" EXACT [GOC:TermGenie] +is_a: GO:0018931 ! naphthalene metabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: yaf +creation_date: 2012-07-19T09:33:50Z + +[Term] +id: GO:1901171 +name: naphthalene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of naphthalene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00082] +synonym: "naphthalene anabolism" EXACT [GOC:TermGenie] +synonym: "naphthalene biosynthesis" EXACT [GOC:TermGenie] +synonym: "naphthalene formation" EXACT [GOC:TermGenie] +synonym: "naphthalene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018931 ! naphthalene metabolic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: yaf +creation_date: 2012-07-19T09:34:11Z + +[Term] +id: GO:1901172 +name: phytoene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytoene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00799] +synonym: "phytoene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:47:46Z + +[Term] +id: GO:1901173 +name: phytoene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phytoene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00799] +synonym: "phytoene breakdown" EXACT [GOC:TermGenie] +synonym: "phytoene catabolism" EXACT [GOC:TermGenie] +synonym: "phytoene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901172 ! phytoene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:07Z + +[Term] +id: GO:1901174 +name: phytoene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phytoene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00799] +synonym: "phytoene anabolism" EXACT [GOC:TermGenie] +synonym: "phytoene biosynthesis" EXACT [GOC:TermGenie] +synonym: "phytoene formation" EXACT [GOC:TermGenie] +synonym: "phytoene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901172 ! phytoene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:15Z + +[Term] +id: GO:1901175 +name: lycopene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lycopene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00803] +synonym: "lycopene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:20Z + +[Term] +id: GO:1901176 +name: lycopene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lycopene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00803] +synonym: "lycopene breakdown" EXACT [GOC:TermGenie] +synonym: "lycopene catabolism" EXACT [GOC:TermGenie] +synonym: "lycopene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901175 ! lycopene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:41Z + +[Term] +id: GO:1901177 +name: lycopene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lycopene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00803] +synonym: "lycopene anabolism" EXACT [GOC:TermGenie] +synonym: "lycopene biosynthesis" EXACT [GOC:TermGenie] +synonym: "lycopene formation" EXACT [GOC:TermGenie] +synonym: "lycopene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901175 ! lycopene metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:49Z + +[Term] +id: GO:1901178 +name: spheroidene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving spheroidene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00683] +synonym: "spheroidene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016122 ! xanthophyll metabolic process +is_a: GO:0018904 ! ether metabolic process +created_by: yaf +creation_date: 2012-07-19T09:48:54Z + +[Term] +id: GO:1901179 +name: spheroidene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of spheroidene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00683] +synonym: "spheroidene breakdown" EXACT [GOC:TermGenie] +synonym: "spheroidene catabolism" EXACT [GOC:TermGenie] +synonym: "spheroidene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:1901178 ! spheroidene metabolic process +is_a: GO:1901502 ! ether catabolic process +created_by: yaf +creation_date: 2012-07-19T09:49:14Z + +[Term] +id: GO:1901180 +name: spheroidene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of spheroidene." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00683] +synonym: "spheroidene anabolism" EXACT [GOC:TermGenie] +synonym: "spheroidene biosynthesis" EXACT [GOC:TermGenie] +synonym: "spheroidene formation" EXACT [GOC:TermGenie] +synonym: "spheroidene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:1901178 ! spheroidene metabolic process +is_a: GO:1901503 ! ether biosynthetic process +created_by: yaf +creation_date: 2012-07-19T09:49:22Z + +[Term] +id: GO:1901181 +name: negative regulation of cellular response to caffeine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine." [GOC:TermGenie] +synonym: "down regulation of cellular response to caffeine" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to caffeine" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to caffeine" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to caffeine" NARROW [GOC:TermGenie] +is_a: GO:2001039 ! negative regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071313 ! cellular response to caffeine +relationship: negatively_regulates GO:0071313 ! cellular response to caffeine +created_by: al +creation_date: 2012-07-19T04:11:46Z + +[Term] +id: GO:1901182 +name: regulation of camalexin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of camalexin biosynthetic process." [GOC:TermGenie] +synonym: "regulation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "regulation of camalexin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0052319 ! regulation of phytoalexin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010120 ! camalexin biosynthetic process +relationship: regulates GO:0010120 ! camalexin biosynthetic process +created_by: tb +creation_date: 2012-07-23T02:16:52Z + +[Term] +id: GO:1901183 +name: positive regulation of camalexin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process." [GOC:TermGenie] +synonym: "activation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of camalexin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "activation of camalexin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of camalexin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of camalexin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of camalexin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of camalexin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of camalexin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of camalexin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of camalexin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of camalexin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of camalexin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of camalexin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0052322 ! positive regulation of phytoalexin biosynthetic process +is_a: GO:1901182 ! regulation of camalexin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010120 ! camalexin biosynthetic process +relationship: positively_regulates GO:0010120 ! camalexin biosynthetic process +created_by: tb +creation_date: 2012-07-23T02:17:21Z + +[Term] +id: GO:1901184 +name: regulation of ERBB signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ERBB signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038127 ! ERBB signaling pathway +relationship: regulates GO:0038127 ! ERBB signaling pathway +created_by: rl +creation_date: 2012-07-24T07:37:11Z + +[Term] +id: GO:1901185 +name: negative regulation of ERBB signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "inhibition of ERBB signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1901184 ! regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038127 ! ERBB signaling pathway +relationship: negatively_regulates GO:0038127 ! ERBB signaling pathway +created_by: rl +creation_date: 2012-07-24T07:37:35Z + +[Term] +id: GO:1901186 +name: positive regulation of ERBB signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "activation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "activation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "activation of ERBB signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of EGF receptor family signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of EGFR family signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of ErbB signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of ERBB signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of ERBB signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1901184 ! regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038127 ! ERBB signaling pathway +relationship: positively_regulates GO:0038127 ! ERBB signaling pathway +created_by: rl +creation_date: 2012-07-24T07:37:43Z + +[Term] +id: GO:1901187 +name: regulation of ephrin receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048013 ! ephrin receptor signaling pathway +relationship: regulates GO:0048013 ! ephrin receptor signaling pathway +created_by: rl +creation_date: 2012-07-24T07:41:49Z + +[Term] +id: GO:1901188 +name: negative regulation of ephrin receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of ephrin receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1901187 ! regulation of ephrin receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048013 ! ephrin receptor signaling pathway +relationship: negatively_regulates GO:0048013 ! ephrin receptor signaling pathway +created_by: rl +creation_date: 2012-07-24T07:42:14Z + +[Term] +id: GO:1901189 +name: positive regulation of ephrin receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway." [GOC:BHF, GOC:TermGenie] +synonym: "activation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "activation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "activation of ephrin receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Eph receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Eph receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of ephrin receptor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1901187 ! regulation of ephrin receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048013 ! ephrin receptor signaling pathway +relationship: positively_regulates GO:0048013 ! ephrin receptor signaling pathway +created_by: rl +creation_date: 2012-07-24T07:42:21Z + +[Term] +id: GO:1901190 +name: regulation of formation of translation initiation ternary complex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] +synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001677 ! formation of translation initiation ternary complex +relationship: regulates GO:0001677 ! formation of translation initiation ternary complex +created_by: ss +creation_date: 2012-07-25T02:26:58Z + +[Term] +id: GO:1901191 +name: negative regulation of formation of translation initiation ternary complex +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] +synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] +synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0045947 ! negative regulation of translational initiation +is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex +relationship: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex +created_by: ss +creation_date: 2012-07-25T02:27:21Z + +[Term] +id: GO:1901192 +name: positive regulation of formation of translation initiation ternary complex +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] +synonym: "activation of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] +synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] +synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0045948 ! positive regulation of translational initiation +is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001677 ! formation of translation initiation ternary complex +relationship: positively_regulates GO:0001677 ! formation of translation initiation ternary complex +created_by: ss +creation_date: 2012-07-25T02:27:29Z + +[Term] +id: GO:1901193 +name: regulation of formation of translation preinitiation complex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex." [GOC:TermGenie] +synonym: "regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:1904688 ! regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001731 ! formation of translation preinitiation complex +relationship: regulates GO:0001731 ! formation of translation preinitiation complex +created_by: ss +creation_date: 2012-07-25T02:31:20Z + +[Term] +id: GO:1901194 +name: negative regulation of formation of translation preinitiation complex +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex." [GOC:TermGenie] +synonym: "down regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "down regulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "down regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "down-regulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "down-regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "downregulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "downregulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "inhibition of formation of translation preinitiation complex" NARROW [GOC:TermGenie] +synonym: "inhibition of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "negative regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1901193 ! regulation of formation of translation preinitiation complex +is_a: GO:1904689 ! negative regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001731 ! formation of translation preinitiation complex +relationship: negatively_regulates GO:0001731 ! formation of translation preinitiation complex +created_by: ss +creation_date: 2012-07-25T02:31:41Z + +[Term] +id: GO:1901195 +name: positive regulation of formation of translation preinitiation complex +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex." [GOC:TermGenie] +synonym: "activation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "activation of formation of translation preinitiation complex" NARROW [GOC:TermGenie] +synonym: "activation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "positive regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "up regulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "up regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "up-regulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "up-regulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of formation of translation pre-initiation complex" EXACT [GOC:TermGenie] +synonym: "upregulation of formation of translation preinitiation complex" EXACT [GOC:TermGenie] +synonym: "upregulation of translation preinitiation complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1901193 ! regulation of formation of translation preinitiation complex +is_a: GO:1904690 ! positive regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001731 ! formation of translation preinitiation complex +relationship: positively_regulates GO:0001731 ! formation of translation preinitiation complex +created_by: ss +creation_date: 2012-07-25T02:31:50Z + +[Term] +id: GO:1901196 +name: positive regulation of calcium-mediated signaling involved in cellular response to salt stress +namespace: biological_process +def: "Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress." [GOC:TermGenie] +synonym: "activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" NARROW [GOC:TermGenie] +synonym: "activation of calcium-mediated signaling involved in cellular response to salt stress" NARROW [GOC:TermGenie] +synonym: "activation of calcium-mediated signaling involved in cellular salinity response" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signaling involved in cellular salinity response" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signalling involved in cellular response to salt stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signalling involved in cellular salinity response" EXACT [GOC:TermGenie] +synonym: "stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" NARROW [GOC:TermGenie] +synonym: "stimulation of calcium-mediated signaling involved in cellular response to salt stress" NARROW [GOC:TermGenie] +synonym: "stimulation of calcium-mediated signaling involved in cellular salinity response" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium-mediated signaling involved in cellular response to salt stress" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium-mediated signaling involved in cellular salinity response" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-mediated signaling involved in cellular response to salt stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-mediated signaling involved in cellular salinity response" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-mediated signaling involved in cellular response to salt stress" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-mediated signaling involved in cellular salinity response" EXACT [GOC:TermGenie] +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +intersection_of: GO:0050850 ! positive regulation of calcium-mediated signaling +intersection_of: part_of GO:0071472 ! cellular response to salt stress +relationship: part_of GO:0071472 ! cellular response to salt stress +created_by: al +creation_date: 2012-07-27T10:52:56Z + +[Term] +id: GO:1901197 +name: positive regulation of calcium-mediated signaling involved in cellular response to calcium ion +namespace: biological_process +def: "Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion." [GOC:TermGenie] +synonym: "activation of calcium-mediated signaling involved in cellular response to Ca2+ ion" NARROW [GOC:TermGenie] +synonym: "activation of calcium-mediated signaling involved in cellular response to calcium ion" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-mediated signalling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] +synonym: "stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" NARROW [GOC:TermGenie] +synonym: "stimulation of calcium-mediated signaling involved in cellular response to calcium ion" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium-mediated signaling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-mediated signaling involved in response to calcium ion" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-mediated signaling involved in cellular response to calcium ion" EXACT [GOC:TermGenie] +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +intersection_of: GO:0050850 ! positive regulation of calcium-mediated signaling +intersection_of: part_of GO:0071277 ! cellular response to calcium ion +relationship: part_of GO:0071277 ! cellular response to calcium ion +created_by: al +creation_date: 2012-07-27T10:57:56Z + +[Term] +id: GO:1901198 +name: positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion +namespace: biological_process +def: "Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion." [GOC:TermGenie] +synonym: "positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion" EXACT [GOC:TermGenie] +is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol +intersection_of: GO:0010524 ! positive regulation of calcium ion transport into cytosol +intersection_of: part_of GO:0071277 ! cellular response to calcium ion +relationship: part_of GO:0071277 ! cellular response to calcium ion +created_by: al +creation_date: 2012-07-27T11:07:43Z + +[Term] +id: GO:1901199 +name: positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress +namespace: biological_process +def: "Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie] +synonym: "positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium ion transport into cytosol involved in cellular salinity response" EXACT [GOC:TermGenie] +is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol +intersection_of: GO:0010524 ! positive regulation of calcium ion transport into cytosol +intersection_of: part_of GO:0071472 ! cellular response to salt stress +relationship: part_of GO:0071472 ! cellular response to salt stress +created_by: al +creation_date: 2012-07-27T11:09:37Z + +[Term] +id: GO:1901200 +name: negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress +namespace: biological_process +def: "Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress." [GOC:TermGenie] +synonym: "negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of calcium ion transport into cytosol involved in cellular salinity response" EXACT [GOC:TermGenie] +is_a: GO:0010523 ! negative regulation of calcium ion transport into cytosol +intersection_of: GO:0010523 ! negative regulation of calcium ion transport into cytosol +intersection_of: part_of GO:0071472 ! cellular response to salt stress +relationship: part_of GO:0071472 ! cellular response to salt stress +created_by: al +creation_date: 2012-07-27T11:11:09Z + +[Term] +id: GO:1901201 +name: regulation of extracellular matrix assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0085029 ! extracellular matrix assembly +relationship: regulates GO:0085029 ! extracellular matrix assembly +created_by: rl +creation_date: 2012-07-27T04:04:00Z + +[Term] +id: GO:1901202 +name: negative regulation of extracellular matrix assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of extracellular matrix assembly" NARROW [GOC:TermGenie] +is_a: GO:1901201 ! regulation of extracellular matrix assembly +is_a: GO:1903054 ! negative regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0085029 ! extracellular matrix assembly +relationship: negatively_regulates GO:0085029 ! extracellular matrix assembly +created_by: rl +creation_date: 2012-07-27T04:04:24Z + +[Term] +id: GO:1901203 +name: positive regulation of extracellular matrix assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] +synonym: "activation of extracellular matrix assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:1901201 ! regulation of extracellular matrix assembly +is_a: GO:1903055 ! positive regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0085029 ! extracellular matrix assembly +relationship: positively_regulates GO:0085029 ! extracellular matrix assembly +created_by: rl +creation_date: 2012-07-27T04:04:32Z + +[Term] +id: GO:1901204 +name: obsolete regulation of adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: hjd +creation_date: 2012-07-30T18:32:51Z + +[Term] +id: GO:1901205 +name: obsolete negative regulation of adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "down regulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "down-regulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "downregulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of adrenergic receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "inhibition of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "negative regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: hjd +creation_date: 2012-07-30T18:33:14Z + +[Term] +id: GO:1901206 +name: obsolete positive regulation of adrenergic receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "activation of adrenergic receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "activation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "positive regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "up regulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "up-regulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "upregulation of adrenergic receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of adrenergic receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-adrenergic receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: hjd +creation_date: 2012-07-30T18:33:22Z + +[Term] +id: GO:1901207 +name: regulation of heart looping +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heart looping." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of cardiac looping" EXACT [GOC:TermGenie] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001947 ! heart looping +relationship: regulates GO:0001947 ! heart looping +created_by: rl +creation_date: 2012-07-31T07:15:47Z + +[Term] +id: GO:1901208 +name: negative regulation of heart looping +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heart looping." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "down regulation of heart looping" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart looping" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "downregulation of heart looping" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac looping" EXACT [GOC:TermGenie] +synonym: "inhibition of heart looping" NARROW [GOC:TermGenie] +synonym: "negative regulation of cardiac looping" EXACT [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1901207 ! regulation of heart looping +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001947 ! heart looping +relationship: negatively_regulates GO:0001947 ! heart looping +created_by: rl +creation_date: 2012-07-31T07:16:10Z + +[Term] +id: GO:1901209 +name: positive regulation of heart looping +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heart looping." [GOC:BHF, GOC:TermGenie] +synonym: "activation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "activation of heart looping" NARROW [GOC:TermGenie] +synonym: "positive regulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "up regulation of heart looping" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart looping" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac looping" EXACT [GOC:TermGenie] +synonym: "upregulation of heart looping" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1901207 ! regulation of heart looping +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001947 ! heart looping +relationship: positively_regulates GO:0001947 ! heart looping +created_by: rl +creation_date: 2012-07-31T07:16:18Z + +[Term] +id: GO:1901210 +name: regulation of cardiac chamber formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie] +is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003207 ! cardiac chamber formation +relationship: regulates GO:0003207 ! cardiac chamber formation +created_by: rl +creation_date: 2012-07-31T07:18:35Z + +[Term] +id: GO:1901211 +name: negative regulation of cardiac chamber formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac chamber formation" NARROW [GOC:TermGenie] +synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie] +is_a: GO:1901210 ! regulation of cardiac chamber formation +is_a: GO:1901220 ! negative regulation of cardiac chamber morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003207 ! cardiac chamber formation +relationship: negatively_regulates GO:0003207 ! cardiac chamber formation +created_by: rl +creation_date: 2012-07-31T07:18:57Z + +[Term] +id: GO:1901212 +name: positive regulation of cardiac chamber formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of cardiac chamber formation" NARROW [GOC:TermGenie] +synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie] +synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie] +is_a: GO:1901210 ! regulation of cardiac chamber formation +is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003207 ! cardiac chamber formation +relationship: positively_regulates GO:0003207 ! cardiac chamber formation +created_by: rl +creation_date: 2012-07-31T07:19:05Z + +[Term] +id: GO:1901213 +name: regulation of transcription from RNA polymerase II promoter involved in heart development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time." [GOC:BHF, GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0007507 ! heart development +relationship: part_of GO:0007507 ! heart development +created_by: rl +creation_date: 2012-07-31T07:26:45Z + +[Term] +id: GO:1901214 +name: regulation of neuron death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] +synonym: "regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "regulation of neuronal cell death" EXACT [GOC:TermGenie] +is_a: GO:0010941 ! regulation of cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070997 ! neuron death +relationship: regulates GO:0070997 ! neuron death +created_by: rph +creation_date: 2012-08-02T09:57:41Z + +[Term] +id: GO:1901215 +name: negative regulation of neuron death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] +synonym: "down regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron death" EXACT [GOC:TermGenie] +synonym: "down regulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron death" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron death" EXACT [GOC:TermGenie] +synonym: "downregulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "inhibition of neuron cell death" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron death" NARROW [GOC:TermGenie] +synonym: "inhibition of neuronal cell death" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuronal cell death" EXACT [GOC:TermGenie] +is_a: GO:0060548 ! negative regulation of cell death +is_a: GO:1901214 ! regulation of neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070997 ! neuron death +relationship: negatively_regulates GO:0070997 ! neuron death +created_by: rph +creation_date: 2012-08-02T09:58:07Z + +[Term] +id: GO:1901216 +name: positive regulation of neuron death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] +synonym: "activation of neuron cell death" NARROW [GOC:TermGenie] +synonym: "activation of neuron death" NARROW [GOC:TermGenie] +synonym: "activation of neuronal cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "up regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "up regulation of neuron death" EXACT [GOC:TermGenie] +synonym: "up regulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuron death" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuronal cell death" EXACT [GOC:TermGenie] +synonym: "upregulation of neuron cell death" EXACT [GOC:TermGenie] +synonym: "upregulation of neuron death" EXACT [GOC:TermGenie] +synonym: "upregulation of neuronal cell death" EXACT [GOC:TermGenie] +is_a: GO:0010942 ! positive regulation of cell death +is_a: GO:1901214 ! regulation of neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070997 ! neuron death +relationship: positively_regulates GO:0070997 ! neuron death +created_by: rph +creation_date: 2012-08-02T09:58:15Z + +[Term] +id: GO:1901217 +name: regulation of holin activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of holin activity." [GOC:bm, GOC:TermGenie] +is_a: GO:0022898 ! regulation of transmembrane transporter activity +is_a: GO:0051709 ! regulation of killing of cells of other organism +is_a: GO:1902186 ! regulation of viral release from host cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034290 ! holin activity +relationship: regulates GO:0034290 ! holin activity +created_by: bf +creation_date: 2012-08-06T10:47:38Z + +[Term] +id: GO:1901218 +name: negative regulation of holin activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of holin activity." [GOC:bm, GOC:TermGenie] +synonym: "antiholin activity" EXACT [] +synonym: "down regulation of holin activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of holin activity" EXACT [GOC:TermGenie] +synonym: "downregulation of holin activity" EXACT [GOC:TermGenie] +synonym: "inhibition of holin activity" NARROW [GOC:TermGenie] +synonym: "phage antiholin" NARROW [GOC:bm] +is_a: GO:0032410 ! negative regulation of transporter activity +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:0051711 ! negative regulation of killing of cells of other organism +is_a: GO:1901217 ! regulation of holin activity +is_a: GO:1902187 ! negative regulation of viral release from host cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034290 ! holin activity +relationship: negatively_regulates GO:0034290 ! holin activity +created_by: bf +creation_date: 2012-08-06T10:48:00Z + +[Term] +id: GO:1901219 +name: regulation of cardiac chamber morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003206 ! cardiac chamber morphogenesis +relationship: regulates GO:0003206 ! cardiac chamber morphogenesis +created_by: rl +creation_date: 2012-08-06T17:59:11Z + +[Term] +id: GO:1901220 +name: negative regulation of cardiac chamber morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of heart chamber morphogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis +relationship: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis +created_by: rl +creation_date: 2012-08-06T17:59:34Z + +[Term] +id: GO:1901221 +name: positive regulation of cardiac chamber morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] +synonym: "activation of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of heart chamber morphogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003206 ! cardiac chamber morphogenesis +relationship: positively_regulates GO:0003206 ! cardiac chamber morphogenesis +created_by: rl +creation_date: 2012-08-06T17:59:42Z + +[Term] +id: GO:1901222 +name: regulation of NIK/NF-kappaB signaling +namespace: biological_process +alt_id: GO:0042345 +alt_id: GO:0042348 +def: "Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling." [GOC:TermGenie] +synonym: "NF-kappaB import into nucleus" NARROW [] +synonym: "NF-KB import into nucleus" NARROW [GOC:bf] +synonym: "regulation of NF-kappaB import into nucleus" NARROW [] +synonym: "regulation of NIK/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038061 ! NIK/NF-kappaB signaling +relationship: regulates GO:0038061 ! NIK/NF-kappaB signaling +created_by: hjd +creation_date: 2012-08-06T20:27:17Z + +[Term] +id: GO:1901223 +name: negative regulation of NIK/NF-kappaB signaling +namespace: biological_process +alt_id: GO:0042347 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling." [GOC:TermGenie] +synonym: "down regulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "down regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "down regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "down regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "down-regulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "down-regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "down-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "down-regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "downregulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "downregulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "downregulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of NIK/NF-kappaB cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "inhibition of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "inhibition of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "negative regulation of NF-kappaB import into nucleus" NARROW [] +synonym: "negative regulation of NIK/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "negative regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "negative regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "negative regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +is_a: GO:1901222 ! regulation of NIK/NF-kappaB signaling +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038061 ! NIK/NF-kappaB signaling +relationship: negatively_regulates GO:0038061 ! NIK/NF-kappaB signaling +created_by: hjd +creation_date: 2012-08-06T20:27:39Z + +[Term] +id: GO:1901224 +name: positive regulation of NIK/NF-kappaB signaling +namespace: biological_process +alt_id: GO:0008588 +alt_id: GO:0042346 +def: "Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling." [GOC:TermGenie] +synonym: "activation of NIK/NF-kappaB cascade" NARROW [GOC:TermGenie] +synonym: "activation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "activation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "activation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytoplasmic NF-kappaB storage" NARROW [] +synonym: "positive regulation of NF-kappaB import into nucleus" NARROW [] +synonym: "positive regulation of NIK/NF-kappaB cascade" RELATED [GOC:signaling] +synonym: "positive regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "positive regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "positive regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "release of cytoplasmic sequestered NF-kappaB" NARROW [] +synonym: "release of NF-kappaB sequestered in cytoplasm" NARROW [] +synonym: "up regulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "up regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "up regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "up-regulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "up-regulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "up-regulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +synonym: "upregulation of NIK/NF-kappaB cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of non-canonical NF-KB signaling" BROAD [GOC:TermGenie] +synonym: "upregulation of noncanonical NF-kappaB signaling" BROAD [GOC:TermGenie] +synonym: "upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway" BROAD [GOC:TermGenie] +synonym: "upregulation of p52-dependent NF-kappaB signaling" NARROW [GOC:TermGenie] +is_a: GO:1901222 ! regulation of NIK/NF-kappaB signaling +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038061 ! NIK/NF-kappaB signaling +relationship: positively_regulates GO:0038061 ! NIK/NF-kappaB signaling +created_by: hjd +creation_date: 2012-08-06T20:27:47Z + +[Term] +id: GO:1901225 +name: obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development." [GOC:BHF, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "downregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter involved in heart development" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "inhibition of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [] +is_obsolete: true +created_by: rl +creation_date: 2012-08-07T07:04:07Z + +[Term] +id: GO:1901226 +name: obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development." [GOC:BHF, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "activation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "activation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter involved in heart development" NARROW [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "activation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [] +synonym: "up regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription regulation from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription regulation from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "upregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: rl +creation_date: 2012-08-07T07:04:32Z + +[Term] +id: GO:1901227 +name: negative regulation of transcription from RNA polymerase II promoter involved in heart development +namespace: biological_process +def: "Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in heart development" NARROW [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1901213 ! regulation of transcription from RNA polymerase II promoter involved in heart development +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0007507 ! heart development +created_by: pr +creation_date: 2012-08-07T12:50:30Z + +[Term] +id: GO:1901228 +name: positive regulation of transcription from RNA polymerase II promoter involved in heart development +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development." [GOC:BHF, GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in heart development" NARROW [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in heart development" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in heart development" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in heart development" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1901213 ! regulation of transcription from RNA polymerase II promoter involved in heart development +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0007507 ! heart development +created_by: pr +creation_date: 2012-08-07T12:53:01Z + +[Term] +id: GO:1901229 +name: regulation of non-canonical Wnt signaling pathway via JNK cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [] +synonym: "regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "regulation of non-canonical Wnt-activated signaling pathway via JNK cascade" EXACT [GOC:signaling] +is_a: GO:2000050 ! regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +relationship: regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +created_by: vk +creation_date: 2012-08-07T14:14:16Z + +[Term] +id: GO:1901230 +name: negative regulation of non-canonical Wnt signaling pathway via JNK cascade +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "inhibition of non-canonical Wnt receptor signaling pathway via JNK cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of non-canonical Wnt receptor signalling pathway via JNK cascade" NARROW [GOC:TermGenie] +synonym: "negative regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [] +synonym: "negative regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of non-canonical Wnt-activated signaling pathway via JNK cascade" RELATED [GOC:signaling] +is_a: GO:1901229 ! regulation of non-canonical Wnt signaling pathway via JNK cascade +is_a: GO:2000051 ! negative regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +relationship: negatively_regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +created_by: vk +creation_date: 2012-08-07T14:14:39Z + +[Term] +id: GO:1901231 +name: positive regulation of non-canonical Wnt signaling pathway via JNK cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade." [GOC:BHF, GOC:TermGenie] +synonym: "activation of non-canonical Wnt receptor signaling pathway via JNK cascade" NARROW [GOC:TermGenie] +synonym: "activation of non-canonical Wnt receptor signalling pathway via JNK cascade" NARROW [GOC:TermGenie] +synonym: "positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [] +synonym: "positive regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "positive regulation of non-canonical Wnt-activated signaling pathway via JNK cascade" EXACT [GOC:signaling] +synonym: "up regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of non-canonical Wnt receptor signaling pathway via JNK cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of non-canonical Wnt receptor signalling pathway via JNK cascade" EXACT [GOC:TermGenie] +is_a: GO:1901229 ! regulation of non-canonical Wnt signaling pathway via JNK cascade +is_a: GO:2000052 ! positive regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +relationship: positively_regulates GO:0038031 ! non-canonical Wnt signaling pathway via JNK cascade +created_by: vk +creation_date: 2012-08-07T14:14:48Z + +[Term] +id: GO:1901232 +name: regulation of convergent extension involved in axis elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation." [GOC:BHF, GOC:TermGenie] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060028 ! convergent extension involved in axis elongation +relationship: regulates GO:0060028 ! convergent extension involved in axis elongation +created_by: vk +creation_date: 2012-08-07T14:21:46Z + +[Term] +id: GO:1901233 +name: negative regulation of convergent extension involved in axis elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in axis elongation" NARROW [GOC:TermGenie] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1901232 ! regulation of convergent extension involved in axis elongation +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060028 ! convergent extension involved in axis elongation +relationship: negatively_regulates GO:0060028 ! convergent extension involved in axis elongation +created_by: vk +creation_date: 2012-08-07T14:22:11Z + +[Term] +id: GO:1901234 +name: positive regulation of convergent extension involved in axis elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of convergent extension involved in axis elongation" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in axis elongation" EXACT [GOC:TermGenie] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1901232 ! regulation of convergent extension involved in axis elongation +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060028 ! convergent extension involved in axis elongation +relationship: positively_regulates GO:0060028 ! convergent extension involved in axis elongation +created_by: vk +creation_date: 2012-08-07T14:22:19Z + +[Term] +id: GO:1901235 +name: (R)-carnitine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of (R)-carnitine from one side of a membrane to the other." [GOC:TermGenie, PMID:16365042, PMID:20357772, PMID:20829798] +xref: RHEA:34959 +is_a: GO:0015226 ! carnitine transmembrane transporter activity +is_a: GO:0090482 ! vitamin transmembrane transporter activity +relationship: part_of GO:1902270 ! (R)-carnitine transmembrane transport +created_by: jl +creation_date: 2012-08-07T14:46:17Z + +[Term] +id: GO:1901236 +name: 4-(trimethylammonio)butanoate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other." [GOC:TermGenie, PMID:16952940, PMID:21784948] +xref: RHEA:32835 +is_a: GO:0015651 ! quaternary ammonium group transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +created_by: jl +creation_date: 2012-08-07T14:46:52Z + +[Term] +id: GO:1901238 +name: ATPase-coupled tungstate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901237 +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out)." [GOC:TermGenie, PMID:16952940, PMID:21784948] +synonym: "tungstate transmembrane transporter activity" BROAD [] +synonym: "tungstate transmembrane-transporting ATPase activity" RELATED [] +xref: EC:7.3.2.6 +xref: RHEA:35027 +is_a: GO:0043225 ! ATPase-coupled inorganic anion transmembrane transporter activity +created_by: jl +creation_date: 2012-08-07T14:47:36Z + +[Term] +id: GO:1901239 +name: malonate(1-) transmembrane transporter activity +namespace: molecular_function +alt_id: GO:1901549 +def: "Enables the transfer of malonate(1-) from one side of a membrane to the other." [GOC:TermGenie, PMID:9128730, PMID:9573154] +synonym: "malonic acid uptake transmembrane transporter activity" RELATED [] +xref: RHEA:33115 +is_a: GO:0005310 ! dicarboxylic acid transmembrane transporter activity +relationship: part_of GO:1901553 ! malonic acid transmembrane transport +created_by: al +creation_date: 2012-08-07T15:09:02Z + +[Term] +id: GO:1901241 +name: 4-hydroxyphenylacetate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other." [GOC:TermGenie, PMID:9315705] +xref: RHEA:33175 +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity +created_by: jl +creation_date: 2012-08-07T15:09:49Z + +[Term] +id: GO:1901242 +name: ATPase-coupled doxorubicin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out)." [GOC:TermGenie, PMID:12057006] +synonym: "doxorubicin transmembrane-transporting ATPase activity" RELATED [] +is_a: GO:0015101 ! organic cation transmembrane transporter activity +is_a: GO:0015665 ! alcohol transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +created_by: jl +creation_date: 2012-08-07T15:10:13Z + +[Term] +id: GO:1901243 +name: ATPase-coupled methionine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + methionine(in) = ADP + phosphate + methionine(out)." [GOC:TermGenie, PMID:12169620, PMID:12819857] +synonym: "ATP-dependent methionine transmembrane transporter activity" EXACT [] +synonym: "methionine transmembrane-transporting ATPase activity" RELATED [] +xref: RHEA:32827 +is_a: GO:0015424 ! ATPase-coupled amino acid transmembrane transporter activity +is_a: GO:0043865 ! methionine transmembrane transporter activity +created_by: jl +creation_date: 2012-08-07T15:59:50Z + +[Term] +id: GO:1901244 +name: obsolete positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus." [GOC:kmv, GOC:TermGenie] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of global transcription from RNA polymerase II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defence response to fungi" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defence response to fungus" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defense response to fungi" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defense response to fungus" NARROW [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defense response to fungus" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungi" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungus" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungi" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungus" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defense response to fungus" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defense response to fungus" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungus" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungi" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungus" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungi" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungus" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defence response to fungi" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defence response to fungus" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defense response to fungi" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defense response to fungus" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: kmv +creation_date: 2012-08-07T18:40:02Z + +[Term] +id: GO:1901245 +name: positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization +namespace: biological_process +def: "The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling." [GOC:amm, GOC:bf, GOC:TermGenie, PMID:18513998] +synonym: "BCR-induced TLR9 recruitment" NARROW [PMID:18513998] +synonym: "positive regulation of TLR9 signaling pathway by B cell receptor internalization" EXACT [GOC:TermGenie] +synonym: "positive regulation of TLR9 signaling pathway by BCR endocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of TLR9 signaling pathway by BCR receptor internalization" EXACT [GOC:TermGenie] +synonym: "positive regulation of toll-like receptor 9 signaling pathway by BCR endocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of toll-like receptor 9 signaling pathway by BCR receptor internalization" EXACT [GOC:TermGenie] +synonym: "positive regulation of toll-like receptor 9 signalling pathway by B cell receptor internalization" EXACT [GOC:TermGenie] +synonym: "positive regulation of toll-like receptor 9 signalling pathway by BCR endocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of toll-like receptor 9 signalling pathway by BCR receptor internalization" EXACT [GOC:TermGenie] +is_a: GO:0034165 ! positive regulation of toll-like receptor 9 signaling pathway +is_a: GO:0036300 ! B cell receptor internalization +is_a: GO:0038010 ! positive regulation of signal transduction by receptor internalization +intersection_of: GO:0036300 ! B cell receptor internalization +intersection_of: positively_regulates GO:0034162 ! toll-like receptor 9 signaling pathway +created_by: bf +creation_date: 2012-08-08T08:12:44Z + +[Term] +id: GO:1901246 +name: regulation of lung ciliated cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061141 ! lung ciliated cell differentiation +relationship: regulates GO:0061141 ! lung ciliated cell differentiation +created_by: vk +creation_date: 2012-08-08T08:58:34Z + +[Term] +id: GO:1901247 +name: negative regulation of lung ciliated cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of lung ciliated cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901246 ! regulation of lung ciliated cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061141 ! lung ciliated cell differentiation +relationship: negatively_regulates GO:0061141 ! lung ciliated cell differentiation +created_by: vk +creation_date: 2012-08-08T08:58:58Z + +[Term] +id: GO:1901248 +name: positive regulation of lung ciliated cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of lung ciliated cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901246 ! regulation of lung ciliated cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061141 ! lung ciliated cell differentiation +relationship: positively_regulates GO:0061141 ! lung ciliated cell differentiation +created_by: vk +creation_date: 2012-08-08T08:59:05Z + +[Term] +id: GO:1901249 +name: regulation of lung goblet cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lung goblet cell differentiation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060480 ! lung goblet cell differentiation +relationship: regulates GO:0060480 ! lung goblet cell differentiation +created_by: vk +creation_date: 2012-08-08T08:59:12Z + +[Term] +id: GO:1901250 +name: negative regulation of lung goblet cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of lung goblet cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of pulmonary goblet cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901249 ! regulation of lung goblet cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060480 ! lung goblet cell differentiation +relationship: negatively_regulates GO:0060480 ! lung goblet cell differentiation +created_by: vk +creation_date: 2012-08-08T08:59:36Z + +[Term] +id: GO:1901251 +name: positive regulation of lung goblet cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of lung goblet cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of pulmonary goblet cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of lung goblet cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of pulmonary goblet cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901249 ! regulation of lung goblet cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060480 ! lung goblet cell differentiation +relationship: positively_regulates GO:0060480 ! lung goblet cell differentiation +created_by: vk +creation_date: 2012-08-08T08:59:44Z + +[Term] +id: GO:1901252 +name: regulation of intracellular transport of viral material +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of egress of virus within host cell." [GOC:bf, GOC:jl, GOC:TermGenie] +synonym: "regulation of egress of virus within host cell" RELATED [] +synonym: "regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "regulation of viral egress" EXACT [GOC:TermGenie] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051049 ! regulation of transport +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0075733 ! intracellular transport of virus +relationship: regulates GO:0075733 ! intracellular transport of virus +created_by: ss +creation_date: 2012-08-09T05:45:25Z + +[Term] +id: GO:1901253 +name: negative regulation of intracellular transport of viral material +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material." [GOC:bf, GOC:jl, GOC:TermGenie] +synonym: "down regulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "down regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "down regulation of viral egress" EXACT [GOC:TermGenie] +synonym: "down-regulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral egress" EXACT [GOC:TermGenie] +synonym: "downregulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "downregulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "downregulation of viral egress" EXACT [GOC:TermGenie] +synonym: "inhibition of egress of virus within host cell" NARROW [GOC:TermGenie] +synonym: "inhibition of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "inhibition of viral egress" EXACT [GOC:TermGenie] +synonym: "negative regulation of egress of virus within host cell" RELATED [] +synonym: "negative regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral egress" EXACT [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1901252 ! regulation of intracellular transport of viral material +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0075733 ! intracellular transport of virus +relationship: negatively_regulates GO:0075733 ! intracellular transport of virus +created_by: ss +creation_date: 2012-08-09T05:45:47Z + +[Term] +id: GO:1901254 +name: positive regulation of intracellular transport of viral material +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material." [GOC:bf, GOC:jl, GOC:TermGenie] +synonym: "activation of egress of virus within host cell" NARROW [GOC:TermGenie] +synonym: "activation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "activation of viral egress" EXACT [GOC:TermGenie] +synonym: "positive regulation of egress of virus within host cell" RELATED [] +synonym: "positive regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral egress" EXACT [GOC:TermGenie] +synonym: "up regulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "up regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "up regulation of viral egress" EXACT [GOC:TermGenie] +synonym: "up-regulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral egress" EXACT [GOC:TermGenie] +synonym: "upregulation of egress of virus within host cell" EXACT [GOC:TermGenie] +synonym: "upregulation of movement of virus within host cell" EXACT [GOC:TermGenie] +synonym: "upregulation of viral egress" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1901252 ! regulation of intracellular transport of viral material +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0075733 ! intracellular transport of virus +relationship: positively_regulates GO:0075733 ! intracellular transport of virus +created_by: ss +creation_date: 2012-08-09T05:45:54Z + +[Term] +id: GO:1901255 +name: nucleotide-excision repair involved in interstrand cross-link repair +namespace: biological_process +def: "Any nucleotide-excision repair that is involved in interstrand cross-link repair." [GOC:TermGenie, PMID:22064477] +synonym: "NER involved in ICL repair" EXACT [GOC:TermGenie] +synonym: "NER involved in interstrand cross-link repair" EXACT [GOC:TermGenie] +synonym: "nucleotide-excision repair involved in ICL repair" EXACT [GOC:TermGenie] +is_a: GO:0006289 ! nucleotide-excision repair +intersection_of: GO:0006289 ! nucleotide-excision repair +intersection_of: part_of GO:0036297 ! interstrand cross-link repair +relationship: part_of GO:0036297 ! interstrand cross-link repair +created_by: vw +creation_date: 2012-08-09T06:09:50Z + +[Term] +id: GO:1901256 +name: regulation of macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of M-CSF production" EXACT [GOC:TermGenie] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036301 ! macrophage colony-stimulating factor production +relationship: regulates GO:0036301 ! macrophage colony-stimulating factor production +created_by: vk +creation_date: 2012-08-10T08:28:08Z + +[Term] +id: GO:1901257 +name: negative regulation of macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "down regulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +synonym: "down-regulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "down-regulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +synonym: "downregulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "downregulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +synonym: "inhibition of M-CSF production" EXACT [GOC:TermGenie] +synonym: "inhibition of macrophage colony-stimulating factor production" NARROW [GOC:TermGenie] +synonym: "negative regulation of M-CSF production" EXACT [GOC:TermGenie] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:1901256 ! regulation of macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036301 ! macrophage colony-stimulating factor production +relationship: negatively_regulates GO:0036301 ! macrophage colony-stimulating factor production +created_by: vk +creation_date: 2012-08-10T08:28:28Z + +[Term] +id: GO:1901258 +name: positive regulation of macrophage colony-stimulating factor production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production." [GOC:BHF, GOC:TermGenie] +synonym: "activation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "activation of macrophage colony-stimulating factor production" NARROW [GOC:TermGenie] +synonym: "positive regulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "up regulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "up regulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +synonym: "up-regulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "up-regulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +synonym: "upregulation of M-CSF production" EXACT [GOC:TermGenie] +synonym: "upregulation of macrophage colony-stimulating factor production" EXACT [GOC:TermGenie] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:1901256 ! regulation of macrophage colony-stimulating factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036301 ! macrophage colony-stimulating factor production +relationship: positively_regulates GO:0036301 ! macrophage colony-stimulating factor production +created_by: vk +creation_date: 2012-08-10T08:28:36Z + +[Term] +id: GO:1901259 +name: chloroplast rRNA processing +namespace: biological_process +def: "Any rRNA processing that takes place in chloroplast." [GOC:TermGenie] +is_a: GO:0006364 ! rRNA processing +intersection_of: GO:0006364 ! rRNA processing +intersection_of: occurs_in GO:0009507 ! chloroplast +relationship: occurs_in GO:0009507 ! chloroplast +property_value: RO:0002161 NCBITaxon:28009 +property_value: RO:0002161 NCBITaxon:33208 +property_value: RO:0002161 NCBITaxon:4751 +property_value: RO:0002161 NCBITaxon:554915 +created_by: tb +creation_date: 2012-08-10T17:43:19Z + +[Term] +id: GO:1901260 +name: peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification +namespace: biological_process +def: "Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification." [GOC:imk, GOC:TermGenie, PMID:22706199] +synonym: "EF-P lysine hydroxylation" RELATED [PMID:3555234] +is_a: GO:0017185 ! peptidyl-lysine hydroxylation +intersection_of: GO:0017185 ! peptidyl-lysine hydroxylation +intersection_of: part_of GO:0072580 ! bacterial-type EF-P lysine modification +relationship: part_of GO:0072580 ! bacterial-type EF-P lysine modification +created_by: bf +creation_date: 2012-08-14T13:20:12Z + +[Term] +id: GO:1901261 +name: regulation of sorocarp spore cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation." [GOC:rjd, GOC:TermGenie] +is_a: GO:0031156 ! regulation of sorocarp development +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044671 ! sorocarp spore cell differentiation +relationship: regulates GO:0044671 ! sorocarp spore cell differentiation +created_by: jl +creation_date: 2012-08-15T09:44:30Z + +[Term] +id: GO:1901262 +name: negative regulation of sorocarp spore cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation." [GOC:rjd, GOC:TermGenie] +synonym: "down regulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of sorocarp spore cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1901261 ! regulation of sorocarp spore cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044671 ! sorocarp spore cell differentiation +relationship: negatively_regulates GO:0044671 ! sorocarp spore cell differentiation +created_by: jl +creation_date: 2012-08-15T09:44:50Z + +[Term] +id: GO:1901263 +name: positive regulation of sorocarp spore cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation." [GOC:rjd, GOC:TermGenie] +synonym: "activation of sorocarp spore cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of sorocarp spore cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1901261 ! regulation of sorocarp spore cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044671 ! sorocarp spore cell differentiation +relationship: positively_regulates GO:0044671 ! sorocarp spore cell differentiation +created_by: jl +creation_date: 2012-08-15T09:44:58Z + +[Term] +id: GO:1901264 +name: carbohydrate derivative transport +namespace: biological_process +def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +created_by: bf +creation_date: 2012-08-16T14:51:22Z + +[Term] +id: GO:1901265 +name: nucleoside phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with nucleoside phosphate." [GOC:TermGenie] +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: bf +creation_date: 2012-08-17T12:59:58Z + +[Term] +id: GO:1901266 +name: cephalosporin C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cephalosporin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00172] +synonym: "cephalosporin C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0043645 ! cephalosporin metabolic process +created_by: yaf +creation_date: 2012-08-17T14:25:59Z + +[Term] +id: GO:1901267 +name: cephalosporin C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cephalosporin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00172] +synonym: "cephalosporin C breakdown" EXACT [GOC:TermGenie] +synonym: "cephalosporin C catabolism" EXACT [GOC:TermGenie] +synonym: "cephalosporin C degradation" EXACT [GOC:TermGenie] +is_a: GO:0030655 ! beta-lactam antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:1901266 ! cephalosporin C metabolic process +created_by: yaf +creation_date: 2012-08-17T14:26:19Z + +[Term] +id: GO:1901268 +name: cephalosporin C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cephalosporin C." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00172] +synonym: "cephalosporin C anabolism" EXACT [GOC:TermGenie] +synonym: "cephalosporin C biosynthesis" EXACT [GOC:TermGenie] +synonym: "cephalosporin C formation" EXACT [GOC:TermGenie] +synonym: "cephalosporin C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043646 ! cephalosporin biosynthetic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1901266 ! cephalosporin C metabolic process +created_by: yaf +creation_date: 2012-08-17T14:26:31Z + +[Term] +id: GO:1901269 +name: lipooligosaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipooligosaccharide." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00501] +synonym: "lipooligosaccharide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: yaf +creation_date: 2012-08-17T14:31:26Z + +[Term] +id: GO:1901270 +name: lipooligosaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00501] +synonym: "lipooligosaccharide breakdown" EXACT [GOC:TermGenie] +synonym: "lipooligosaccharide catabolism" EXACT [GOC:TermGenie] +synonym: "lipooligosaccharide degradation" EXACT [GOC:TermGenie] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:1901269 ! lipooligosaccharide metabolic process +created_by: yaf +creation_date: 2012-08-17T14:31:48Z + +[Term] +id: GO:1901271 +name: lipooligosaccharide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipooligosaccharide." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00501] +synonym: "lipooligosaccharide anabolism" EXACT [GOC:TermGenie] +synonym: "lipooligosaccharide biosynthesis" EXACT [GOC:TermGenie] +synonym: "lipooligosaccharide formation" EXACT [GOC:TermGenie] +synonym: "lipooligosaccharide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009312 ! oligosaccharide biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:1901269 ! lipooligosaccharide metabolic process +created_by: yaf +creation_date: 2012-08-17T14:31:55Z + +[Term] +id: GO:1901272 +name: 2-dehydro-3-deoxy-D-gluconic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00856] +synonym: "2-dehydro-3-deoxy-D-gluconic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0019520 ! aldonic acid metabolic process +created_by: yaf +creation_date: 2012-08-17T14:46:15Z + +[Term] +id: GO:1901273 +name: 2-dehydro-3-deoxy-D-gluconic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00856] +synonym: "2-dehydro-3-deoxy-D-gluconic acid breakdown" EXACT [GOC:TermGenie] +synonym: "2-dehydro-3-deoxy-D-gluconic acid catabolism" EXACT [GOC:TermGenie] +synonym: "2-dehydro-3-deoxy-D-gluconic acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0046176 ! aldonic acid catabolic process +is_a: GO:0046365 ! monosaccharide catabolic process +is_a: GO:1901272 ! 2-dehydro-3-deoxy-D-gluconic acid metabolic process +created_by: yaf +creation_date: 2012-08-17T14:46:37Z + +[Term] +id: GO:1901274 +name: 2-dehydro-3-deoxy-D-gluconic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00856] +synonym: "2-dehydro-3-deoxy-D-gluconic acid anabolism" EXACT [GOC:TermGenie] +synonym: "2-dehydro-3-deoxy-D-gluconic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "2-dehydro-3-deoxy-D-gluconic acid formation" EXACT [GOC:TermGenie] +synonym: "2-dehydro-3-deoxy-D-gluconic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046175 ! aldonic acid biosynthetic process +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:1901272 ! 2-dehydro-3-deoxy-D-gluconic acid metabolic process +created_by: yaf +creation_date: 2012-08-17T14:46:44Z + +[Term] +id: GO:1901275 +name: tartrate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tartrate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00839] +synonym: "tartrate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008152 ! metabolic process +created_by: yaf +creation_date: 2012-08-17T14:52:19Z + +[Term] +id: GO:1901276 +name: tartrate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tartrate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00839] +synonym: "tartrate breakdown" EXACT [GOC:TermGenie] +synonym: "tartrate catabolism" EXACT [GOC:TermGenie] +synonym: "tartrate degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process +is_a: GO:1901275 ! tartrate metabolic process +created_by: yaf +creation_date: 2012-08-17T14:52:40Z + +[Term] +id: GO:1901277 +name: tartrate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tartrate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00839] +synonym: "tartrate anabolism" EXACT [GOC:TermGenie] +synonym: "tartrate biosynthesis" EXACT [GOC:TermGenie] +synonym: "tartrate formation" EXACT [GOC:TermGenie] +synonym: "tartrate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:1901275 ! tartrate metabolic process +created_by: yaf +creation_date: 2012-08-17T14:52:48Z + +[Term] +id: GO:1901278 +name: D-ribose 5-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-ribose 5-phosphate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00293] +synonym: "D-ribose 5-phosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019693 ! ribose phosphate metabolic process +created_by: yaf +creation_date: 2012-08-17T14:59:58Z + +[Term] +id: GO:1901279 +name: D-ribose 5-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00293] +synonym: "D-ribose 5-phosphate breakdown" EXACT [GOC:TermGenie] +synonym: "D-ribose 5-phosphate catabolism" EXACT [GOC:TermGenie] +synonym: "D-ribose 5-phosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:1901278 ! D-ribose 5-phosphate metabolic process +created_by: yaf +creation_date: 2012-08-17T15:00:19Z + +[Term] +id: GO:1901280 +name: D-ribose 5-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00293] +synonym: "D-ribose 5-phosphate anabolism" EXACT [GOC:TermGenie] +synonym: "D-ribose 5-phosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "D-ribose 5-phosphate formation" EXACT [GOC:TermGenie] +synonym: "D-ribose 5-phosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046390 ! ribose phosphate biosynthetic process +is_a: GO:1901278 ! D-ribose 5-phosphate metabolic process +created_by: yaf +creation_date: 2012-08-17T15:00:27Z + +[Term] +id: GO:1901281 +name: fructoselysine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fructoselysine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00784] +synonym: "fructosyllysine breakdown" EXACT [GOC:TermGenie] +synonym: "fructosyllysine catabolic process" EXACT [] +synonym: "fructosyllysine catabolism" EXACT [GOC:TermGenie] +synonym: "fructosyllysine degradation" EXACT [GOC:TermGenie] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:0030392 ! fructosamine catabolic process +is_a: GO:0030393 ! fructoselysine metabolic process +created_by: yaf +creation_date: 2012-08-17T15:04:43Z + +[Term] +id: GO:1901282 +name: fructoselysine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fructoselysine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00784] +synonym: "fructosyllysine anabolism" EXACT [GOC:TermGenie] +synonym: "fructosyllysine biosynthesis" EXACT [GOC:TermGenie] +synonym: "fructosyllysine biosynthetic process" EXACT [] +synonym: "fructosyllysine formation" EXACT [GOC:TermGenie] +synonym: "fructosyllysine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:0030391 ! fructosamine biosynthetic process +is_a: GO:0030393 ! fructoselysine metabolic process +created_by: yaf +creation_date: 2012-08-17T15:05:05Z + +[Term] +id: GO:1901283 +name: 5,6,7,8-tetrahydromethanopterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00065] +synonym: "5,6,7,8-tetrahydromethanopterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043648 ! dicarboxylic acid metabolic process +is_a: GO:2001117 ! tetrahydromethanopterin metabolic process +created_by: yaf +creation_date: 2012-08-17T15:32:33Z + +[Term] +id: GO:1901284 +name: 5,6,7,8-tetrahydromethanopterin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00065] +synonym: "5,6,7,8-tetrahydromethanopterin breakdown" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydromethanopterin catabolism" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydromethanopterin degradation" EXACT [GOC:TermGenie] +is_a: GO:0042560 ! pteridine-containing compound catabolic process +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901283 ! 5,6,7,8-tetrahydromethanopterin metabolic process +created_by: yaf +creation_date: 2012-08-17T15:32:54Z + +[Term] +id: GO:1901285 +name: 5,6,7,8-tetrahydromethanopterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00065] +synonym: "5,6,7,8-tetrahydromethanopterin anabolism" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydromethanopterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydromethanopterin formation" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydromethanopterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:1901283 ! 5,6,7,8-tetrahydromethanopterin metabolic process +is_a: GO:2001118 ! tetrahydromethanopterin biosynthetic process +created_by: yaf +creation_date: 2012-08-17T15:33:02Z + +[Term] +id: GO:1901286 +name: iron-sulfur-molybdenum cofactor metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00782] +synonym: "FeMo-co metabolic process" EXACT [GOC:yaf] +synonym: "FeMo-co metabolism" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor metabolic process" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor metabolism" EXACT [GOC:yaf] +synonym: "iron-sulfur-molybdenum cofactor metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051186 ! cofactor metabolic process +created_by: yaf +creation_date: 2012-08-17T15:39:14Z + +[Term] +id: GO:1901287 +name: iron-sulfur-molybdenum cofactor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00782] +synonym: "FeMo-co breakdown" EXACT [GOC:yaf] +synonym: "FeMo-co catabolic process" EXACT [GOC:yaf] +synonym: "FeMo-co catabolism" EXACT [GOC:yaf] +synonym: "FeMo-co degradation" EXACT [GOC:yaf] +synonym: "iron-molybdenum breakdown" EXACT [GOC:yaf] +synonym: "iron-molybdenum catabolic process" EXACT [GOC:yaf] +synonym: "iron-molybdenum catabolism" EXACT [GOC:yaf] +synonym: "iron-molybdenum degradation" EXACT [GOC:yaf] +synonym: "iron-sulfur-molybdenum cofactor breakdown" EXACT [GOC:TermGenie] +synonym: "iron-sulfur-molybdenum cofactor catabolism" EXACT [GOC:TermGenie] +synonym: "iron-sulfur-molybdenum cofactor degradation" EXACT [GOC:TermGenie] +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:1901286 ! iron-sulfur-molybdenum cofactor metabolic process +created_by: yaf +creation_date: 2012-08-17T15:39:36Z + +[Term] +id: GO:1901288 +name: iron-sulfur-molybdenum cofactor biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00782] +synonym: "FeMo-co anabolism" EXACT [GOC:yaf] +synonym: "FeMo-co biosynthesis" EXACT [GOC:yaf] +synonym: "FeMo-co biosynthetic process" EXACT [GOC:yaf] +synonym: "FeMo-co formation" EXACT [GOC:yaf] +synonym: "FeMo-co synthesis" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor anabolism" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor biosynthesis" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor biosynthetic process" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor formation" EXACT [GOC:yaf] +synonym: "iron-molybdenum cofactor synthesis" EXACT [GOC:yaf] +synonym: "iron-sulfur-molybdenum cofactor anabolism" EXACT [GOC:TermGenie] +synonym: "iron-sulfur-molybdenum cofactor biosynthesis" EXACT [GOC:TermGenie] +synonym: "iron-sulfur-molybdenum cofactor formation" EXACT [GOC:TermGenie] +synonym: "iron-sulfur-molybdenum cofactor synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1901286 ! iron-sulfur-molybdenum cofactor metabolic process +created_by: yaf +creation_date: 2012-08-17T15:39:48Z + +[Term] +id: GO:1901289 +name: succinyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of succinyl-CoA." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00929] +synonym: "succinyl-CoA breakdown" EXACT [GOC:TermGenie] +synonym: "succinyl-CoA catabolism" EXACT [GOC:TermGenie] +synonym: "succinyl-CoA degradation" EXACT [GOC:TermGenie] +is_a: GO:0006104 ! succinyl-CoA metabolic process +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +created_by: yaf +creation_date: 2012-08-17T16:13:37Z + +[Term] +id: GO:1901290 +name: succinyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of succinyl-CoA." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00929] +synonym: "succinyl-CoA anabolism" EXACT [GOC:TermGenie] +synonym: "succinyl-CoA biosynthesis" EXACT [GOC:TermGenie] +synonym: "succinyl-CoA formation" EXACT [GOC:TermGenie] +synonym: "succinyl-CoA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006104 ! succinyl-CoA metabolic process +is_a: GO:0071616 ! acyl-CoA biosynthetic process +created_by: yaf +creation_date: 2012-08-17T16:13:57Z + +[Term] +id: GO:1901291 +name: negative regulation of double-strand break repair via single-strand annealing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing." [GOC:sart, GOC:TermGenie] +synonym: "down regulation of double-strand break repair via single-strand annealing" EXACT [GOC:TermGenie] +synonym: "down-regulation of double-strand break repair via single-strand annealing" EXACT [GOC:TermGenie] +synonym: "downregulation of double-strand break repair via single-strand annealing" EXACT [GOC:TermGenie] +synonym: "inhibition of double-strand break repair via single-strand annealing" NARROW [GOC:TermGenie] +is_a: GO:2000780 ! negative regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045002 ! double-strand break repair via single-strand annealing +relationship: negatively_regulates GO:0045002 ! double-strand break repair via single-strand annealing +created_by: sart +creation_date: 2012-08-20T09:03:03Z + +[Term] +id: GO:1901292 +name: nucleoside phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate." [GOC:TermGenie] +synonym: "nucleoside phosphate breakdown" EXACT [GOC:TermGenie] +synonym: "nucleoside phosphate catabolism" EXACT [GOC:TermGenie] +synonym: "nucleoside phosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0006753 ! nucleoside phosphate metabolic process +is_a: GO:0034404 ! nucleobase-containing small molecule biosynthetic process +is_a: GO:0034655 ! nucleobase-containing compound catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +created_by: bf +creation_date: 2012-08-20T12:33:25Z + +[Term] +id: GO:1901293 +name: nucleoside phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a nucleoside phosphate." [GOC:TermGenie] +synonym: "nucleoside phosphate anabolism" EXACT [GOC:TermGenie] +synonym: "nucleoside phosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "nucleoside phosphate formation" EXACT [GOC:TermGenie] +synonym: "nucleoside phosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006753 ! nucleoside phosphate metabolic process +is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +created_by: bf +creation_date: 2012-08-20T12:33:45Z + +[Term] +id: GO:1901294 +name: obsolete negative regulation of SREBP signaling pathway by negative regulation of DNA binding +namespace: biological_process +def: "OBSOLETE. Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway." [GOC:TermGenie, PMID:22017871] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +synonym: "inhibition of SREBP-dependent transcription by blocking DNA binding" EXACT [PMID:22017871] +synonym: "negative regulation of SREBP signaling pathway by down regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP signaling pathway by down-regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP signaling pathway by downregulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP signaling pathway by inhibition of DNA binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway by down regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway by down-regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway by downregulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway by inhibition of DNA binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway by negative regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by down regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by down-regulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by downregulation of DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by inhibition of DNA binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by negative regulation of DNA binding" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2012-08-20T14:11:03Z + +[Term] +id: GO:1901295 +name: regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:signaling] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:1905066 ! regulation of canonical Wnt signaling pathway involved in heart development +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +relationship: regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +created_by: vk +creation_date: 2012-08-21T09:06:32Z + +[Term] +id: GO:1901296 +name: negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:signaling] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:1901295 ! regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +is_a: GO:1905067 ! negative regulation of canonical Wnt signaling pathway involved in heart development +is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +relationship: negatively_regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +created_by: vk +creation_date: 2012-08-21T09:06:52Z + +[Term] +id: GO:1901297 +name: positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment." [GOC:BHF, GOC:TermGenie] +synonym: "activation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:signaling] +synonym: "up regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment" EXACT [GOC:TermGenie] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:1901295 ! regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +is_a: GO:1905068 ! positive regulation of canonical Wnt signaling pathway involved in heart development +is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +relationship: positively_regulates GO:0061317 ! canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment +created_by: vk +creation_date: 2012-08-21T09:06:59Z + +[Term] +id: GO:1901298 +name: regulation of hydrogen peroxide-mediated programmed cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death." [GOC:BHF, GOC:TermGenie] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:1903205 ! regulation of hydrogen peroxide-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +relationship: regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +created_by: vk +creation_date: 2012-08-21T09:44:59Z + +[Term] +id: GO:1901299 +name: negative regulation of hydrogen peroxide-mediated programmed cell death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +synonym: "inhibition of hydrogen peroxide-mediated programmed cell death" NARROW [GOC:TermGenie] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:1901298 ! regulation of hydrogen peroxide-mediated programmed cell death +is_a: GO:1903206 ! negative regulation of hydrogen peroxide-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +relationship: negatively_regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +created_by: vk +creation_date: 2012-08-21T09:45:21Z + +[Term] +id: GO:1901300 +name: positive regulation of hydrogen peroxide-mediated programmed cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death." [GOC:BHF, GOC:TermGenie] +synonym: "activation of hydrogen peroxide-mediated programmed cell death" NARROW [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide-mediated programmed cell death" EXACT [GOC:TermGenie] +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:1901298 ! regulation of hydrogen peroxide-mediated programmed cell death +is_a: GO:1905206 ! positive regulation of hydrogen peroxide-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +relationship: positively_regulates GO:0010421 ! hydrogen peroxide-mediated programmed cell death +created_by: vk +creation_date: 2012-08-21T09:45:29Z + +[Term] +id: GO:1901301 +name: regulation of cargo loading into COPII-coated vesicle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle." [GOC:lb, GOC:TermGenie, PMID:15899885] +synonym: "regulation of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090110 ! COPII-coated vesicle cargo loading +relationship: regulates GO:0090110 ! COPII-coated vesicle cargo loading +created_by: bf +creation_date: 2012-08-21T13:03:00Z + +[Term] +id: GO:1901303 +name: negative regulation of cargo loading into COPII-coated vesicle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle." [GOC:lb, GOC:TermGenie, PMID:15899885] +synonym: "down regulation of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of cargo loading into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of cargo loading into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of cargo loading into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "inhibition of cargo loading into COPII-coated vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "inhibition of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of COPII vesicle protein binding" NARROW [PMID:15899885] +synonym: "inhibition of protein sorting into COPII-coated vesicles" EXACT [PMID:15899885] +synonym: "negative regulation of cargo loading into COPII vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of cargo selection into COPII-coated vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of COPII coat-cargo complex assembly" RELATED [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:1901301 ! regulation of cargo loading into COPII-coated vesicle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090110 ! COPII-coated vesicle cargo loading +relationship: negatively_regulates GO:0090110 ! COPII-coated vesicle cargo loading +created_by: bf +creation_date: 2012-08-21T13:05:46Z + +[Term] +id: GO:1901304 +name: regulation of spermidine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spermidine biosynthetic process." [GOC:pm, GOC:TermGenie] +synonym: "regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "regulation of spermidine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010967 ! regulation of polyamine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008295 ! spermidine biosynthetic process +relationship: regulates GO:0008295 ! spermidine biosynthetic process +created_by: pm +creation_date: 2012-08-21T13:58:23Z + +[Term] +id: GO:1901305 +name: negative regulation of spermidine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process." [GOC:pm, GOC:TermGenie] +synonym: "down regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of spermidine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of spermidine formation" EXACT [GOC:TermGenie] +synonym: "inhibition of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of spermidine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0033239 ! negative regulation of cellular amine metabolic process +is_a: GO:1901304 ! regulation of spermidine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008295 ! spermidine biosynthetic process +relationship: negatively_regulates GO:0008295 ! spermidine biosynthetic process +created_by: pm +creation_date: 2012-08-21T13:58:45Z + +[Term] +id: GO:1901307 +name: positive regulation of spermidine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process." [GOC:pm, GOC:TermGenie] +synonym: "activation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "activation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of spermidine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "activation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of spermidine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of spermidine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of spermidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of spermidine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of spermidine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of spermidine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0033240 ! positive regulation of cellular amine metabolic process +is_a: GO:1901304 ! regulation of spermidine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008295 ! spermidine biosynthetic process +relationship: positively_regulates GO:0008295 ! spermidine biosynthetic process +created_by: pm +creation_date: 2012-08-21T14:02:58Z + +[Term] +id: GO:1901308 +name: regulation of sterol regulatory element binding protein cleavage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage." [GOC:TermGenie] +synonym: "regulation of SREBP cleavage" EXACT [GOC:TermGenie] +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0070613 ! regulation of protein processing +is_a: GO:2000638 ! regulation of SREBP signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035103 ! sterol regulatory element binding protein cleavage +relationship: regulates GO:0035103 ! sterol regulatory element binding protein cleavage +created_by: bf +creation_date: 2012-08-21T16:43:12Z + +[Term] +id: GO:1901309 +name: negative regulation of sterol regulatory element binding protein cleavage +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage." [GOC:TermGenie, PMID:15899885, PMID:16525117] +synonym: "down regulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "down regulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +synonym: "down-regulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "down-regulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +synonym: "downregulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "downregulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +synonym: "inhibition of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "inhibition of SREBP processing" EXACT [GOC:bf] +synonym: "inhibition of sterol regulatory element binding protein cleavage" NARROW [GOC:TermGenie] +synonym: "negative regulation of SREBP cleavage" EXACT [GOC:TermGenie] +is_a: GO:0010955 ! negative regulation of protein processing +is_a: GO:1901308 ! regulation of sterol regulatory element binding protein cleavage +is_a: GO:2000639 ! negative regulation of SREBP signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035103 ! sterol regulatory element binding protein cleavage +relationship: negatively_regulates GO:0035103 ! sterol regulatory element binding protein cleavage +created_by: bf +creation_date: 2012-08-21T16:43:32Z + +[Term] +id: GO:1901310 +name: positive regulation of sterol regulatory element binding protein cleavage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage." [GOC:TermGenie, PMID:15899885, PMID:16525117] +synonym: "activation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "activation of sterol regulatory element binding protein cleavage" NARROW [GOC:TermGenie] +synonym: "positive regulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "up regulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "up regulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +synonym: "up-regulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "up-regulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +synonym: "upregulation of SREBP cleavage" EXACT [GOC:TermGenie] +synonym: "upregulation of sterol regulatory element binding protein cleavage" EXACT [GOC:TermGenie] +is_a: GO:0010954 ! positive regulation of protein processing +is_a: GO:1901308 ! regulation of sterol regulatory element binding protein cleavage +is_a: GO:2000640 ! positive regulation of SREBP signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035103 ! sterol regulatory element binding protein cleavage +relationship: positively_regulates GO:0035103 ! sterol regulatory element binding protein cleavage +created_by: bf +creation_date: 2012-08-21T16:43:40Z + +[Term] +id: GO:1901311 +name: obsolete regulation of gene expression involved in extracellular matrix organization +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression involved in extracellular matrix organization." [GOC:BHF, GOC:TermGenie] +comment: This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization. +synonym: "regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +is_obsolete: true +consider: GO:0010468 +created_by: vk +creation_date: 2012-08-22T09:18:13Z + +[Term] +id: GO:1901312 +name: obsolete negative regulation of gene expression involved in extracellular matrix organization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gene expression involved in extracellular matrix organization." [GOC:BHF, GOC:TermGenie] +comment: This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization. +synonym: "down regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "down regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "down regulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "down-regulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "downregulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "downregulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "inhibition of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "inhibition of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "inhibition of gene expression involved in extracellular matrix organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "negative regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +is_obsolete: true +consider: GO:0010629 +created_by: vk +creation_date: 2012-08-22T09:18:35Z + +[Term] +id: GO:1901313 +name: obsolete positive regulation of gene expression involved in extracellular matrix organization +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization." [GOC:BHF, GOC:TermGenie] +comment: This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization. +synonym: "activation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "activation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "activation of gene expression involved in extracellular matrix organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "positive regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "up regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "up regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "up regulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "up-regulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "upregulation of expression of extracellular matrix proteins" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular matrix protein production" RELATED [GOC:TermGenie] +synonym: "upregulation of gene expression involved in extracellular matrix organization" EXACT [GOC:TermGenie] +is_obsolete: true +consider: GO:0010628 +created_by: vk +creation_date: 2012-08-22T09:18:42Z + +[Term] +id: GO:1901314 +name: regulation of histone H2A K63-linked ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination." [GOC:TermGenie] +is_a: GO:0033182 ! regulation of histone ubiquitination +is_a: GO:1900044 ! regulation of protein K63-linked ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070535 ! histone H2A K63-linked ubiquitination +relationship: regulates GO:0070535 ! histone H2A K63-linked ubiquitination +created_by: tb +creation_date: 2012-08-22T20:29:04Z + +[Term] +id: GO:1901315 +name: negative regulation of histone H2A K63-linked ubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination." [GOC:TermGenie] +synonym: "down regulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H2A K63-linked ubiquitination" NARROW [GOC:TermGenie] +is_a: GO:0033183 ! negative regulation of histone ubiquitination +is_a: GO:1900045 ! negative regulation of protein K63-linked ubiquitination +is_a: GO:1901314 ! regulation of histone H2A K63-linked ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070535 ! histone H2A K63-linked ubiquitination +relationship: negatively_regulates GO:0070535 ! histone H2A K63-linked ubiquitination +created_by: tb +creation_date: 2012-08-22T20:29:24Z + +[Term] +id: GO:1901316 +name: positive regulation of histone H2A K63-linked ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination." [GOC:TermGenie] +synonym: "activation of histone H2A K63-linked ubiquitination" NARROW [GOC:TermGenie] +synonym: "up regulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H2A K63-linked ubiquitination" EXACT [GOC:TermGenie] +is_a: GO:0033184 ! positive regulation of histone ubiquitination +is_a: GO:1901314 ! regulation of histone H2A K63-linked ubiquitination +is_a: GO:1902523 ! positive regulation of protein K63-linked ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070535 ! histone H2A K63-linked ubiquitination +relationship: positively_regulates GO:0070535 ! histone H2A K63-linked ubiquitination +created_by: tb +creation_date: 2012-08-22T20:29:32Z + +[Term] +id: GO:1901317 +name: regulation of flagellated sperm motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] +synonym: "regulation of sperm motility" BROAD [] +synonym: "regulation of sperm movement" BROAD [GOC:TermGenie] +is_a: GO:1902019 ! regulation of cilium-dependent cell motility +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030317 ! flagellated sperm motility +relationship: regulates GO:0030317 ! flagellated sperm motility +created_by: hjd +creation_date: 2012-08-22T20:50:14Z + +[Term] +id: GO:1901318 +name: negative regulation of flagellated sperm motility +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] +synonym: "down regulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "down regulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "down-regulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "down-regulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "downregulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "downregulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "inhibition of sperm motility" NARROW [GOC:TermGenie] +synonym: "inhibition of sperm movement" BROAD [GOC:TermGenie] +synonym: "negative regulation of sperm motility" BROAD [] +synonym: "negative regulation of sperm movement" BROAD [GOC:TermGenie] +is_a: GO:1901317 ! regulation of flagellated sperm motility +is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030317 ! flagellated sperm motility +relationship: negatively_regulates GO:0030317 ! flagellated sperm motility +created_by: hjd +creation_date: 2012-08-22T20:50:35Z + +[Term] +id: GO:1901319 +name: positive regulation of trehalose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of trehalose catabolic process." [GOC:TermGenie] +synonym: "activation of mycose catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of mycose catabolism" EXACT [GOC:TermGenie] +synonym: "activation of mykose catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of mykose catabolism" EXACT [GOC:TermGenie] +synonym: "activation of trehalose breakdown" EXACT [GOC:TermGenie] +synonym: "activation of trehalose catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of trehalose catabolism" EXACT [GOC:TermGenie] +synonym: "activation of trehalose degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of mycose catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of mycose catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of mykose catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of mykose catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of trehalose breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of trehalose catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of trehalose degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of mycose catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of mycose catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mykose catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of mykose catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of trehalose breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of trehalose catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of trehalose catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of trehalose degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mycose catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mycose catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mykose catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mykose catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of trehalose breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of trehalose catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of trehalose catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of trehalose degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of mycose catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mycose catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mykose catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mykose catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of trehalose breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of trehalose catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of trehalose catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of trehalose degradation" EXACT [GOC:TermGenie] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:0090062 ! regulation of trehalose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005993 ! trehalose catabolic process +relationship: positively_regulates GO:0005993 ! trehalose catabolic process +created_by: al +creation_date: 2012-08-24T12:57:52Z + +[Term] +id: GO:1901320 +name: negative regulation of heart induction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heart induction." [GOC:TermGenie] +synonym: "down regulation of heart induction" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart induction" EXACT [GOC:TermGenie] +synonym: "downregulation of heart induction" EXACT [GOC:TermGenie] +synonym: "inhibition of heart induction" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0090381 ! regulation of heart induction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003129 ! heart induction +relationship: negatively_regulates GO:0003129 ! heart induction +created_by: bf +creation_date: 2012-08-28T15:48:38Z + +[Term] +id: GO:1901321 +name: positive regulation of heart induction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heart induction." [GOC:TermGenie] +synonym: "activation of heart induction" NARROW [GOC:TermGenie] +synonym: "up regulation of heart induction" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart induction" EXACT [GOC:TermGenie] +synonym: "upregulation of heart induction" EXACT [GOC:TermGenie] +is_a: GO:0090381 ! regulation of heart induction +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003129 ! heart induction +relationship: positively_regulates GO:0003129 ! heart induction +created_by: bf +creation_date: 2012-08-28T15:49:51Z + +[Term] +id: GO:1901322 +name: response to chloramphenicol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: tb +creation_date: 2012-08-30T00:01:07Z + +[Term] +id: GO:1901323 +name: response to erythromycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus." [GOC:TermGenie] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-30T10:09:59Z + +[Term] +id: GO:1901324 +name: response to trichodermin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus." [GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +created_by: mah +creation_date: 2012-08-30T10:11:07Z + +[Term] +id: GO:1901325 +name: response to antimycin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-30T10:12:16Z + +[Term] +id: GO:1901326 +name: response to tetracycline +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus." [GOC:TermGenie] +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: mah +creation_date: 2012-08-30T10:13:26Z + +[Term] +id: GO:1901327 +name: response to tacrolimus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus." [GOC:TermGenie] +synonym: "response to FK506" EXACT [CHEBI:61057] +synonym: "response to tacrolimus hydrate" EXACT [CHEBI:61057] +is_a: GO:0042493 ! response to drug +created_by: mah +creation_date: 2012-08-30T10:14:40Z + +[Term] +id: GO:1901328 +name: response to cytochalasin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus." [GOC:TermGenie] +is_a: GO:0010046 ! response to mycotoxin +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061478 ! response to platelet aggregation inhibitor +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-08-30T16:36:35Z + +[Term] +id: GO:1901329 +name: regulation of odontoblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071895 ! odontoblast differentiation +relationship: regulates GO:0071895 ! odontoblast differentiation +created_by: hjd +creation_date: 2012-08-31T16:50:05Z + +[Term] +id: GO:1901330 +name: negative regulation of odontoblast differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] +synonym: "down regulation of odontoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of odontoblast differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of odontoblast differentiation" NARROW [GOC:TermGenie] +is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation +is_a: GO:1901329 ! regulation of odontoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071895 ! odontoblast differentiation +relationship: negatively_regulates GO:0071895 ! odontoblast differentiation +created_by: hjd +creation_date: 2012-08-31T16:50:27Z + +[Term] +id: GO:1901331 +name: positive regulation of odontoblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] +synonym: "activation of odontoblast differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of odontoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of odontoblast differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901329 ! regulation of odontoblast differentiation +is_a: GO:1902913 ! positive regulation of neuroepithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071895 ! odontoblast differentiation +relationship: positively_regulates GO:0071895 ! odontoblast differentiation +created_by: hjd +creation_date: 2012-08-31T16:50:35Z + +[Term] +id: GO:1901332 +name: negative regulation of lateral root development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development." [GOC:TermGenie] +synonym: "down regulation of lateral root development" EXACT [GOC:TermGenie] +synonym: "down-regulation of lateral root development" EXACT [GOC:TermGenie] +synonym: "downregulation of lateral root development" EXACT [GOC:TermGenie] +synonym: "inhibition of lateral root development" NARROW [GOC:TermGenie] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:2000023 ! regulation of lateral root development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048527 ! lateral root development +relationship: negatively_regulates GO:0048527 ! lateral root development +created_by: tb +creation_date: 2012-09-01T00:58:37Z + +[Term] +id: GO:1901333 +name: positive regulation of lateral root development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lateral root development." [GOC:TermGenie] +synonym: "activation of lateral root development" NARROW [GOC:TermGenie] +synonym: "up regulation of lateral root development" EXACT [GOC:TermGenie] +synonym: "up-regulation of lateral root development" EXACT [GOC:TermGenie] +synonym: "upregulation of lateral root development" EXACT [GOC:TermGenie] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:2000023 ! regulation of lateral root development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048527 ! lateral root development +relationship: positively_regulates GO:0048527 ! lateral root development +created_by: tb +creation_date: 2012-09-01T00:59:46Z + +[Term] +id: GO:1901334 +name: lactone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lactone." [GOC:TermGenie] +synonym: "lactone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: bf +creation_date: 2012-09-03T10:26:00Z + +[Term] +id: GO:1901335 +name: lactone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactone." [GOC:TermGenie] +synonym: "lactone breakdown" EXACT [GOC:TermGenie] +synonym: "lactone catabolism" EXACT [GOC:TermGenie] +synonym: "lactone degradation" EXACT [GOC:TermGenie] +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901334 ! lactone metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +created_by: bf +creation_date: 2012-09-03T10:27:11Z + +[Term] +id: GO:1901336 +name: lactone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lactone." [GOC:TermGenie] +synonym: "lactone anabolism" EXACT [GOC:TermGenie] +synonym: "lactone biosynthesis" EXACT [GOC:TermGenie] +synonym: "lactone formation" EXACT [GOC:TermGenie] +synonym: "lactone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901334 ! lactone metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +created_by: bf +creation_date: 2012-09-03T10:27:29Z + +[Term] +id: GO:1901337 +name: thioester transport +namespace: biological_process +def: "The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0072348 ! sulfur compound transport +created_by: bf +creation_date: 2012-09-03T13:14:44Z + +[Term] +id: GO:1901338 +name: catecholamine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with catecholamine." [GOC:TermGenie] +is_a: GO:0097159 ! organic cyclic compound binding +created_by: bf +creation_date: 2012-09-03T14:08:44Z + +[Term] +id: GO:1901339 +name: regulation of store-operated calcium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015279 ! store-operated calcium channel activity +relationship: regulates GO:0015279 ! store-operated calcium channel activity +created_by: pr +creation_date: 2012-09-03T14:23:10Z + +[Term] +id: GO:1901340 +name: negative regulation of store-operated calcium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] +synonym: "down regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of store-operated calcium channel activity" NARROW [GOC:TermGenie] +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:1901339 ! regulation of store-operated calcium channel activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015279 ! store-operated calcium channel activity +relationship: negatively_regulates GO:0015279 ! store-operated calcium channel activity +created_by: pr +creation_date: 2012-09-03T14:24:21Z + +[Term] +id: GO:1901341 +name: positive regulation of store-operated calcium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] +synonym: "activation of store-operated calcium channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:1901339 ! regulation of store-operated calcium channel activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015279 ! store-operated calcium channel activity +relationship: positively_regulates GO:0015279 ! store-operated calcium channel activity +created_by: pr +creation_date: 2012-09-03T14:24:38Z + +[Term] +id: GO:1901342 +name: regulation of vasculature development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie] +synonym: "regulation of vascular system development" RELATED [GOC:TermGenie] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001944 ! vasculature development +relationship: regulates GO:0001944 ! vasculature development +created_by: bf +creation_date: 2012-09-06T09:16:15Z + +[Term] +id: GO:1901343 +name: negative regulation of vasculature development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie] +synonym: "down regulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular system development" RELATED [GOC:TermGenie] +synonym: "inhibition of vasculature development" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular system development" RELATED [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001944 ! vasculature development +relationship: negatively_regulates GO:0001944 ! vasculature development +created_by: bf +creation_date: 2012-09-06T09:17:24Z + +[Term] +id: GO:1901344 +name: response to leptomycin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus." [GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0070542 ! response to fatty acid +created_by: mah +creation_date: 2012-09-07T13:20:47Z + +[Term] +id: GO:1901345 +name: response to L-thialysine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus." [GOC:TermGenie] +synonym: "response to thialysine" BROAD [GOC:mah] +is_a: GO:0043200 ! response to amino acid +created_by: mah +creation_date: 2012-09-07T13:22:49Z + +[Term] +id: GO:1901346 +name: negative regulation of vasculature development involved in avascular cornea development in camera-type eye +namespace: biological_process +def: "Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye." [GOC:TermGenie, GOC:uh, PMID:16849433, PMID:17051153] +synonym: "down regulation of vascular system development involved in avascular cornea development" RELATED [GOC:TermGenie] +synonym: "down regulation of vascular system development involved in avascular cornea development in camera-type eye" RELATED [GOC:TermGenie] +synonym: "down regulation of vasculature development involved in avascular cornea development" EXACT [GOC:TermGenie] +synonym: "down regulation of vasculature development involved in avascular cornea development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular system development involved in avascular cornea development" RELATED [GOC:TermGenie] +synonym: "down-regulation of vascular system development involved in avascular cornea development in camera-type eye" RELATED [GOC:TermGenie] +synonym: "down-regulation of vasculature development involved in avascular cornea development" EXACT [GOC:TermGenie] +synonym: "down-regulation of vasculature development involved in avascular cornea development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular system development involved in avascular cornea development" RELATED [GOC:TermGenie] +synonym: "downregulation of vascular system development involved in avascular cornea development in camera-type eye" RELATED [GOC:TermGenie] +synonym: "downregulation of vasculature development involved in avascular cornea development" EXACT [GOC:TermGenie] +synonym: "downregulation of vasculature development involved in avascular cornea development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular system development involved in avascular cornea development" RELATED [GOC:TermGenie] +synonym: "inhibition of vascular system development involved in avascular cornea development in camera-type eye" RELATED [GOC:TermGenie] +synonym: "inhibition of vasculature development involved in avascular cornea development" NARROW [GOC:TermGenie] +synonym: "inhibition of vasculature development involved in avascular cornea development in camera-type eye" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular system development involved in avascular cornea development" RELATED [GOC:TermGenie] +synonym: "negative regulation of vascular system development involved in avascular cornea development in camera-type eye" RELATED [GOC:TermGenie] +synonym: "negative regulation of vasculature development involved in avascular cornea development" EXACT [GOC:TermGenie] +is_a: GO:1901343 ! negative regulation of vasculature development +intersection_of: GO:1901343 ! negative regulation of vasculature development +intersection_of: part_of GO:0036331 ! avascular cornea development in camera-type eye +relationship: part_of GO:0036331 ! avascular cornea development in camera-type eye +created_by: bf +creation_date: 2012-09-07T15:53:40Z + +[Term] +id: GO:1901347 +name: negative regulation of secondary cell wall biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis." [GOC:TermGenie] +synonym: "down regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "down regulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "down regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "down regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "down-regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "down-regulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "down-regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "down-regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "downregulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "downregulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "downregulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "downregulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "inhibition of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "inhibition of secondary cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "inhibition of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "inhibition of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "negative regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "negative regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "negative regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "negative regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +is_a: GO:1903339 ! negative regulation of cell wall organization or biogenesis +is_a: GO:2000652 ! regulation of secondary cell wall biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009834 ! plant-type secondary cell wall biogenesis +relationship: negatively_regulates GO:0009834 ! plant-type secondary cell wall biogenesis +created_by: tb +creation_date: 2012-09-07T17:58:05Z + +[Term] +id: GO:1901348 +name: positive regulation of secondary cell wall biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis." [GOC:TermGenie] +synonym: "activation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "activation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "activation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "activation of secondary cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "activation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "activation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "positive regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "positive regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "positive regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "positive regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "up regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "up regulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "up regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "up regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "up-regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "up-regulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "up-regulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "up-regulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +synonym: "upregulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of plant-type secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of secondary cell wall anabolism" BROAD [GOC:TermGenie] +synonym: "upregulation of secondary cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of secondary cell wall biosynthetic process" BROAD [GOC:TermGenie] +synonym: "upregulation of secondary cell wall formation" BROAD [GOC:TermGenie] +synonym: "upregulation of secondary cell wall synthesis" BROAD [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:1903340 ! positive regulation of cell wall organization or biogenesis +is_a: GO:2000652 ! regulation of secondary cell wall biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009834 ! plant-type secondary cell wall biogenesis +relationship: positively_regulates GO:0009834 ! plant-type secondary cell wall biogenesis +created_by: tb +creation_date: 2012-09-07T17:59:14Z + +[Term] +id: GO:1901349 +name: glucosinolate transport +namespace: biological_process +def: "The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:0072348 ! sulfur compound transport +is_a: GO:1901264 ! carbohydrate derivative transport +created_by: tb +creation_date: 2012-09-07T22:44:34Z + +[Term] +id: GO:1901350 +name: obsolete cell-cell signaling involved in cell-cell junction organization +namespace: biological_process +def: "OBSOLETE. Any cell-cell signaling that is involved in cell-cell junction organization." [GOC:TermGenie] +comment: The reasons for obsoletion are that: (1) the term was created in 2012 and it had been used for only 1 NAS annotation (UniProt) since then; and (2)\nit can be represented as a GO-CAM. +synonym: "cell-cell signaling involved in cell-cell junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "cell-cell signaling involved in cell-cell junction biogenesis" RELATED [GOC:TermGenie] +synonym: "cell-cell signaling involved in cell-cell junction organisation" EXACT [GOC:TermGenie] +synonym: "cell-cell signaling involved in intercellular junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "cell-cell signalling involved in cell-cell junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "cell-cell signalling involved in cell-cell junction biogenesis" RELATED [GOC:TermGenie] +synonym: "cell-cell signalling involved in cell-cell junction organisation" EXACT [GOC:TermGenie] +synonym: "cell-cell signalling involved in cell-cell junction organization" EXACT [GOC:TermGenie] +synonym: "cell-cell signalling involved in intercellular junction assembly and maintenance" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rph +creation_date: 2012-09-11T09:15:04Z + +[Term] +id: GO:1901351 +name: regulation of phosphatidylglycerol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:12869188] +synonym: "regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +relationship: regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +created_by: dgf +creation_date: 2012-09-12T20:46:37Z + +[Term] +id: GO:1901352 +name: negative regulation of phosphatidylglycerol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:12869188] +synonym: "down regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidylglycerol anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylglycerol biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylglycerol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylglycerol formation" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylglycerol synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +is_a: GO:1901351 ! regulation of phosphatidylglycerol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +relationship: negatively_regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +created_by: dgf +creation_date: 2012-09-12T20:47:53Z + +[Term] +id: GO:1901353 +name: positive regulation of phosphatidylglycerol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process." [GOC:dgf, GOC:TermGenie, PMID:12869188] +synonym: "activation of phosphatidylglycerol anabolism" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylglycerol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylglycerol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylglycerol formation" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylglycerol synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylglycerol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylglycerol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylglycerol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylglycerol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylglycerol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +is_a: GO:1901351 ! regulation of phosphatidylglycerol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +relationship: positively_regulates GO:0006655 ! phosphatidylglycerol biosynthetic process +created_by: dgf +creation_date: 2012-09-12T20:48:11Z + +[Term] +id: GO:1901354 +name: response to L-canavanine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus." [GOC:TermGenie] +is_a: GO:0017085 ! response to insecticide +is_a: GO:0043200 ! response to amino acid +created_by: mah +creation_date: 2012-09-13T13:11:17Z + +[Term] +id: GO:1901355 +name: response to rapamycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: mah +creation_date: 2012-09-13T13:12:26Z + +[Term] +id: GO:1901356 +name: beta-D-galactofuranose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-D-galactofuranose." [GOC:di, GOC:TermGenie] +synonym: "beta-D-galactofuranose metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006012 ! galactose metabolic process +created_by: di +creation_date: 2012-09-13T22:18:20Z + +[Term] +id: GO:1901357 +name: beta-D-galactofuranose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose." [GOC:di, GOC:TermGenie] +synonym: "beta-D-galactofuranose breakdown" EXACT [GOC:TermGenie] +synonym: "beta-D-galactofuranose catabolism" EXACT [GOC:TermGenie] +synonym: "beta-D-galactofuranose degradation" EXACT [GOC:TermGenie] +is_a: GO:0019388 ! galactose catabolic process +is_a: GO:1901356 ! beta-D-galactofuranose metabolic process +created_by: di +creation_date: 2012-09-13T22:19:30Z + +[Term] +id: GO:1901358 +name: beta-D-galactofuranose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose." [GOC:di, GOC:TermGenie] +synonym: "beta-D-galactofuranose anabolism" EXACT [GOC:TermGenie] +synonym: "beta-D-galactofuranose biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-D-galactofuranose formation" EXACT [GOC:TermGenie] +synonym: "beta-D-galactofuranose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046369 ! galactose biosynthetic process +is_a: GO:1901356 ! beta-D-galactofuranose metabolic process +created_by: di +creation_date: 2012-09-13T22:19:47Z + +[Term] +id: GO:1901359 +name: tungstate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tungstate." [GOC:TermGenie] +is_a: GO:0043168 ! anion binding +created_by: crds +creation_date: 2012-09-14T08:33:56Z + +[Term] +id: GO:1901360 +name: organic cyclic compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] +synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: bf +creation_date: 2012-09-14T09:03:51Z + +[Term] +id: GO:1901361 +name: organic cyclic compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." [GOC:TermGenie] +synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie] +synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie] +synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie] +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: bf +creation_date: 2012-09-14T09:05:04Z + +[Term] +id: GO:1901362 +name: organic cyclic compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] +synonym: "organic cyclic compound anabolism" EXACT [GOC:TermGenie] +synonym: "organic cyclic compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "organic cyclic compound formation" EXACT [GOC:TermGenie] +synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: bf +creation_date: 2012-09-14T09:05:22Z + +[Term] +id: GO:1901363 +name: heterocyclic compound binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with heterocyclic compound." [GOC:TermGenie] +is_a: GO:0005488 ! binding +created_by: bf +creation_date: 2012-09-14T13:53:50Z + +[Term] +id: GO:1901364 +name: funalenone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving funalenone." [GOC:di, GOC:TermGenie] +synonym: "funalenone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +created_by: di +creation_date: 2012-09-17T18:24:23Z + +[Term] +id: GO:1901365 +name: funalenone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of funalenone." [GOC:di, GOC:TermGenie] +synonym: "funalenone breakdown" EXACT [GOC:TermGenie] +synonym: "funalenone catabolism" EXACT [GOC:TermGenie] +synonym: "funalenone degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:1901364 ! funalenone metabolic process +created_by: di +creation_date: 2012-09-17T18:25:29Z + +[Term] +id: GO:1901366 +name: funalenone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of funalenone." [GOC:di, GOC:TermGenie] +synonym: "funalenone anabolism" EXACT [GOC:TermGenie] +synonym: "funalenone biosynthesis" EXACT [GOC:TermGenie] +synonym: "funalenone formation" EXACT [GOC:TermGenie] +synonym: "funalenone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901364 ! funalenone metabolic process +created_by: di +creation_date: 2012-09-17T18:25:47Z + +[Term] +id: GO:1901367 +name: response to L-cysteine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus." [GOC:TermGenie] +is_a: GO:0043200 ! response to amino acid +created_by: bf +creation_date: 2012-09-18T13:49:42Z + +[Term] +id: GO:1901369 +name: cyclic 2,3-bisphospho-D-glycerate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid." [GOC:bf, GOC:crds, GOC:TermGenie, PMID:2226838] +synonym: "cDPG biosynthesis" EXACT [PMID:2226838] +synonym: "cyclic 2,3-bisphospho-D-glyceric acid anabolism" EXACT [GOC:TermGenie] +synonym: "cyclic 2,3-bisphospho-D-glyceric acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "cyclic 2,3-bisphospho-D-glyceric acid biosynthetic process" EXACT [CHEBI:28699] +synonym: "cyclic 2,3-bisphospho-D-glyceric acid formation" EXACT [GOC:TermGenie] +synonym: "cyclic 2,3-bisphospho-D-glyceric acid synthesis" EXACT [GOC:TermGenie] +synonym: "cyclic 2,3-diphosphoglycerate biosynthesis" EXACT [CHEBI:28699] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0046175 ! aldonic acid biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +created_by: bf +creation_date: 2012-09-19T14:17:57Z + +[Term] +id: GO:1901370 +name: response to glutathione +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus." [GOC:TermGenie] +is_a: GO:1901652 ! response to peptide +created_by: mah +creation_date: 2012-09-21T13:59:24Z + +[Term] +id: GO:1901371 +name: regulation of leaf morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leaf morphogenesis." [GOC:TermGenie] +is_a: GO:1900618 ! regulation of shoot system morphogenesis +is_a: GO:1905421 ! regulation of plant organ morphogenesis +is_a: GO:2000024 ! regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009965 ! leaf morphogenesis +relationship: regulates GO:0009965 ! leaf morphogenesis +created_by: tb +creation_date: 2012-09-24T23:07:17Z + +[Term] +id: GO:1901372 +name: trehalose biosynthetic process involved in ascospore formation +namespace: biological_process +def: "Any trehalose biosynthetic process that is involved in ascospore formation." [GOC:TermGenie] +synonym: "mycose biosynthesis involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "mycose biosynthesis involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "mycose biosynthetic process involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "mycose biosynthetic process involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "mykose biosynthesis involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "mykose biosynthesis involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "mykose biosynthetic process involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "mykose biosynthetic process involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "trehalose anabolism involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "trehalose anabolism involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "trehalose biosynthesis involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "trehalose biosynthesis involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "trehalose biosynthetic process involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "trehalose formation involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "trehalose formation involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "trehalose synthesis involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "trehalose synthesis involved in ascospore formation" EXACT [GOC:TermGenie] +is_a: GO:0005992 ! trehalose biosynthetic process +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0005992 ! trehalose biosynthetic process +intersection_of: part_of GO:0030437 ! ascospore formation +relationship: part_of GO:0030437 ! ascospore formation +created_by: al +creation_date: 2012-09-25T11:06:48Z + +[Term] +id: GO:1901373 +name: lipid hydroperoxide transport +namespace: biological_process +def: "The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +created_by: tb +creation_date: 2012-09-28T00:24:39Z + +[Term] +id: GO:1901374 +name: acetate ester transport +namespace: biological_process +def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +created_by: bf +creation_date: 2012-09-28T10:42:13Z + +[Term] +id: GO:1901375 +name: acetate ester transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1901374 ! acetate ester transport +created_by: bf +creation_date: 2012-09-28T10:47:08Z + +[Term] +id: GO:1901376 +name: organic heteropentacyclic compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic heteropentacyclic compound." [GOC:TermGenie] +synonym: "organic heteropentacyclic compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: bf +creation_date: 2012-09-28T12:50:41Z + +[Term] +id: GO:1901377 +name: organic heteropentacyclic compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound." [GOC:TermGenie] +synonym: "organic heteropentacyclic compound breakdown" EXACT [GOC:TermGenie] +synonym: "organic heteropentacyclic compound catabolism" EXACT [GOC:TermGenie] +synonym: "organic heteropentacyclic compound degradation" EXACT [GOC:TermGenie] +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: bf +creation_date: 2012-09-28T12:51:51Z + +[Term] +id: GO:1901378 +name: organic heteropentacyclic compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound." [GOC:TermGenie] +synonym: "organic heteropentacyclic compound anabolism" EXACT [GOC:TermGenie] +synonym: "organic heteropentacyclic compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "organic heteropentacyclic compound formation" EXACT [GOC:TermGenie] +synonym: "organic heteropentacyclic compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: bf +creation_date: 2012-09-28T12:52:09Z + +[Term] +id: GO:1901379 +name: regulation of potassium ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of potassium ion membrane transport" EXACT [] +is_a: GO:0043266 ! regulation of potassium ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071805 ! potassium ion transmembrane transport +relationship: regulates GO:0071805 ! potassium ion transmembrane transport +created_by: rl +creation_date: 2012-09-28T15:58:00Z + +[Term] +id: GO:1901380 +name: negative regulation of potassium ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of potassium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of potassium ion membrane transport" EXACT [] +is_a: GO:0043267 ! negative regulation of potassium ion transport +is_a: GO:1901379 ! regulation of potassium ion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071805 ! potassium ion transmembrane transport +relationship: negatively_regulates GO:0071805 ! potassium ion transmembrane transport +created_by: rl +creation_date: 2012-09-28T15:59:08Z + +[Term] +id: GO:1901381 +name: positive regulation of potassium ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport." [GOC:BHF, GOC:TermGenie] +synonym: "activation of potassium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of potassium ion membrane transport" EXACT [] +synonym: "up regulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium ion transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:0043268 ! positive regulation of potassium ion transport +is_a: GO:1901379 ! regulation of potassium ion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071805 ! potassium ion transmembrane transport +relationship: positively_regulates GO:0071805 ! potassium ion transmembrane transport +created_by: rl +creation_date: 2012-09-28T15:59:25Z + +[Term] +id: GO:1901382 +name: regulation of chorionic trophoblast cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097360 ! chorionic trophoblast cell proliferation +relationship: regulates GO:0097360 ! chorionic trophoblast cell proliferation +created_by: vk +creation_date: 2012-10-01T10:03:13Z + +[Term] +id: GO:1901383 +name: negative regulation of chorionic trophoblast cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation +relationship: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation +created_by: vk +creation_date: 2012-10-01T10:04:23Z + +[Term] +id: GO:1901384 +name: positive regulation of chorionic trophoblast cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation +relationship: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation +created_by: vk +creation_date: 2012-10-01T10:04:41Z + +[Term] +id: GO:1901385 +name: regulation of voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005245 ! voltage-gated calcium channel activity +relationship: regulates GO:0005245 ! voltage-gated calcium channel activity +created_by: vk +creation_date: 2012-10-01T10:34:08Z + +[Term] +id: GO:1901386 +name: negative regulation of voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "down regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "down regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "down regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "down-regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "down-regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "down-regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "downregulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "downregulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "downregulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "downregulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "inhibition of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "inhibition of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "inhibition of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage-gated calcium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "negative regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "negative regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "negative regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005245 ! voltage-gated calcium channel activity +relationship: negatively_regulates GO:0005245 ! voltage-gated calcium channel activity +created_by: vk +creation_date: 2012-10-01T10:35:15Z + +[Term] +id: GO:1901387 +name: positive regulation of voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] +synonym: "activation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "activation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "activation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of voltage-gated calcium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "activation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "positive regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "positive regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "positive regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "up regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "up regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "up regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "up-regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "up-regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "up-regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +synonym: "upregulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] +synonym: "upregulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] +synonym: "upregulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] +synonym: "upregulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005245 ! voltage-gated calcium channel activity +relationship: positively_regulates GO:0005245 ! voltage-gated calcium channel activity +created_by: vk +creation_date: 2012-10-01T10:35:32Z + +[Term] +id: GO:1901388 +name: regulation of transforming growth factor beta activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transforming growth factor beta activation." [GOC:sl, GOC:TermGenie] +synonym: "regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFbeta activation" EXACT [GOC:TermGenie] +is_a: GO:0071634 ! regulation of transforming growth factor beta production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036363 ! transforming growth factor beta activation +relationship: regulates GO:0036363 ! transforming growth factor beta activation +created_by: bf +creation_date: 2012-10-01T10:32:00Z + +[Term] +id: GO:1901389 +name: negative regulation of transforming growth factor beta activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation." [GOC:sl, GOC:TermGenie] +synonym: "down regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "down regulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +synonym: "downregulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "downregulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "downregulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +synonym: "inhibition of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "inhibition of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFB activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "inhibition of transforming growth factor beta activation" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFbeta activation" EXACT [GOC:TermGenie] +is_a: GO:0071635 ! negative regulation of transforming growth factor beta production +is_a: GO:1901388 ! regulation of transforming growth factor beta activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036363 ! transforming growth factor beta activation +relationship: negatively_regulates GO:0036363 ! transforming growth factor beta activation +created_by: bf +creation_date: 2012-10-01T10:33:09Z + +[Term] +id: GO:1901390 +name: positive regulation of transforming growth factor beta activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation." [GOC:sl, GOC:TermGenie] +synonym: "activation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "activation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "activation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "activation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "activation of transforming growth factor beta activation" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "up regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "up regulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +synonym: "upregulation of L-TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "upregulation of latent TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGF-B activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGF-beta activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFB activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFbeta activation" EXACT [GOC:TermGenie] +synonym: "upregulation of transforming growth factor beta activation" EXACT [GOC:TermGenie] +is_a: GO:0071636 ! positive regulation of transforming growth factor beta production +is_a: GO:1901388 ! regulation of transforming growth factor beta activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036363 ! transforming growth factor beta activation +relationship: positively_regulates GO:0036363 ! transforming growth factor beta activation +created_by: bf +creation_date: 2012-10-01T10:33:26Z + +[Term] +id: GO:1901392 +name: regulation of transforming growth factor beta1 activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation." [GOC:sl, GOC:TermGenie] +synonym: "regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +is_a: GO:0032908 ! regulation of transforming growth factor beta1 production +is_a: GO:1901388 ! regulation of transforming growth factor beta activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036364 ! transforming growth factor beta1 activation +relationship: regulates GO:0036364 ! transforming growth factor beta1 activation +created_by: bf +creation_date: 2012-10-01T10:40:06Z + +[Term] +id: GO:1901393 +name: negative regulation of transforming growth factor beta1 activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation." [GOC:sl, GOC:TermGenie] +synonym: "down regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of transforming growth factor beta1 activation" NARROW [GOC:TermGenie] +synonym: "inhibition of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +is_a: GO:0032911 ! negative regulation of transforming growth factor beta1 production +is_a: GO:1901389 ! negative regulation of transforming growth factor beta activation +is_a: GO:1901392 ! regulation of transforming growth factor beta1 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036364 ! transforming growth factor beta1 activation +relationship: negatively_regulates GO:0036364 ! transforming growth factor beta1 activation +created_by: bf +creation_date: 2012-10-01T10:41:17Z + +[Term] +id: GO:1901394 +name: positive regulation of transforming growth factor beta1 activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation." [GOC:sl, GOC:TermGenie] +synonym: "activation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "activation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "activation of transforming growth factor beta1 activation" NARROW [GOC:TermGenie] +synonym: "activation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of L-TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of latent-TGF-beta1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGF-beta 1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFB1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFbeta 1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of transforming growth factor beta1 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of transforming growth factor-beta1 activation" EXACT [GOC:TermGenie] +is_a: GO:0032914 ! positive regulation of transforming growth factor beta1 production +is_a: GO:1901390 ! positive regulation of transforming growth factor beta activation +is_a: GO:1901392 ! regulation of transforming growth factor beta1 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036364 ! transforming growth factor beta1 activation +relationship: positively_regulates GO:0036364 ! transforming growth factor beta1 activation +created_by: bf +creation_date: 2012-10-01T10:41:33Z + +[Term] +id: GO:1901395 +name: regulation of transforming growth factor beta2 activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation." [GOC:sl, GOC:TermGenie] +synonym: "regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +is_a: GO:0032909 ! regulation of transforming growth factor beta2 production +is_a: GO:1901388 ! regulation of transforming growth factor beta activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036365 ! transforming growth factor beta2 activation +relationship: regulates GO:0036365 ! transforming growth factor beta2 activation +created_by: bf +creation_date: 2012-10-01T10:46:50Z + +[Term] +id: GO:1901396 +name: negative regulation of transforming growth factor beta2 activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation." [GOC:sl, GOC:TermGenie] +synonym: "down regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of transforming growth factor beta2 activation" NARROW [GOC:TermGenie] +synonym: "negative regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +is_a: GO:0032912 ! negative regulation of transforming growth factor beta2 production +is_a: GO:1901389 ! negative regulation of transforming growth factor beta activation +is_a: GO:1901395 ! regulation of transforming growth factor beta2 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036365 ! transforming growth factor beta2 activation +relationship: negatively_regulates GO:0036365 ! transforming growth factor beta2 activation +created_by: bf +creation_date: 2012-10-01T10:47:59Z + +[Term] +id: GO:1901397 +name: positive regulation of transforming growth factor beta2 activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation." [GOC:sl, GOC:TermGenie] +synonym: "activation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "activation of transforming growth factor beta2 activation" NARROW [GOC:TermGenie] +synonym: "positive regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGF-beta 2 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFB2 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFbeta 2 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of transforming growth factor beta2 activation" EXACT [GOC:TermGenie] +is_a: GO:0032915 ! positive regulation of transforming growth factor beta2 production +is_a: GO:1901390 ! positive regulation of transforming growth factor beta activation +is_a: GO:1901395 ! regulation of transforming growth factor beta2 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036365 ! transforming growth factor beta2 activation +relationship: positively_regulates GO:0036365 ! transforming growth factor beta2 activation +created_by: bf +creation_date: 2012-10-01T10:48:15Z + +[Term] +id: GO:1901398 +name: regulation of transforming growth factor beta3 activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation." [GOC:sl, GOC:TermGenie] +synonym: "regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +is_a: GO:0032910 ! regulation of transforming growth factor beta3 production +is_a: GO:1901388 ! regulation of transforming growth factor beta activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036366 ! transforming growth factor beta3 activation +relationship: regulates GO:0036366 ! transforming growth factor beta3 activation +created_by: bf +creation_date: 2012-10-01T10:49:25Z + +[Term] +id: GO:1901399 +name: negative regulation of transforming growth factor beta3 activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation." [GOC:sl, GOC:TermGenie] +synonym: "down regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "down regulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "downregulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "inhibition of transforming growth factor beta3 activation" NARROW [GOC:TermGenie] +synonym: "negative regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +is_a: GO:0032913 ! negative regulation of transforming growth factor beta3 production +is_a: GO:1901389 ! negative regulation of transforming growth factor beta activation +is_a: GO:1901398 ! regulation of transforming growth factor beta3 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036366 ! transforming growth factor beta3 activation +relationship: negatively_regulates GO:0036366 ! transforming growth factor beta3 activation +created_by: bf +creation_date: 2012-10-01T10:50:32Z + +[Term] +id: GO:1901400 +name: positive regulation of transforming growth factor beta3 activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation." [GOC:sl, GOC:TermGenie] +synonym: "activation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "activation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "activation of transforming growth factor beta3 activation" NARROW [GOC:TermGenie] +synonym: "positive regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "up regulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGF-beta 3 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFB3 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of TGFbeta 3 activation" EXACT [GOC:TermGenie] +synonym: "upregulation of transforming growth factor beta3 activation" EXACT [GOC:TermGenie] +is_a: GO:0032916 ! positive regulation of transforming growth factor beta3 production +is_a: GO:1901390 ! positive regulation of transforming growth factor beta activation +is_a: GO:1901398 ! regulation of transforming growth factor beta3 activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036366 ! transforming growth factor beta3 activation +relationship: positively_regulates GO:0036366 ! transforming growth factor beta3 activation +created_by: bf +creation_date: 2012-10-01T10:50:49Z + +[Term] +id: GO:1901401 +name: regulation of tetrapyrrole metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033013 ! tetrapyrrole metabolic process +relationship: regulates GO:0033013 ! tetrapyrrole metabolic process +created_by: tt +creation_date: 2012-10-01T14:34:03Z + +[Term] +id: GO:1901402 +name: negative regulation of tetrapyrrole metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process +relationship: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process +created_by: tt +creation_date: 2012-10-01T14:35:11Z + +[Term] +id: GO:1901403 +name: positive regulation of tetrapyrrole metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033013 ! tetrapyrrole metabolic process +relationship: positively_regulates GO:0033013 ! tetrapyrrole metabolic process +created_by: tt +creation_date: 2012-10-01T14:35:29Z + +[Term] +id: GO:1901404 +name: regulation of tetrapyrrole catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033015 ! tetrapyrrole catabolic process +relationship: regulates GO:0033015 ! tetrapyrrole catabolic process +created_by: tt +creation_date: 2012-10-01T14:38:12Z + +[Term] +id: GO:1901405 +name: negative regulation of tetrapyrrole catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process +is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process +relationship: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process +created_by: tt +creation_date: 2012-10-01T14:39:22Z + +[Term] +id: GO:1901406 +name: positive regulation of tetrapyrrole catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process +is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033015 ! tetrapyrrole catabolic process +relationship: positively_regulates GO:0033015 ! tetrapyrrole catabolic process +created_by: tt +creation_date: 2012-10-01T14:39:40Z + +[Term] +id: GO:1901407 +name: regulation of phosphorylation of RNA polymerase II C-terminal domain +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain." [GOC:TermGenie] +synonym: "regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +relationship: regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +created_by: vw +creation_date: 2012-10-01T14:39:50Z + +[Term] +id: GO:1901408 +name: negative regulation of phosphorylation of RNA polymerase II C-terminal domain +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain." [GOC:TermGenie] +synonym: "down regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "down-regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down-regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "downregulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "downregulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "downregulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "inhibition of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "inhibition of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "inhibition of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphorylation of RNA polymerase II C-terminal domain" NARROW [GOC:TermGenie] +synonym: "negative regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "negative regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:1901407 ! regulation of phosphorylation of RNA polymerase II C-terminal domain +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +relationship: negatively_regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +created_by: vw +creation_date: 2012-10-01T14:40:58Z + +[Term] +id: GO:1901409 +name: positive regulation of phosphorylation of RNA polymerase II C-terminal domain +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain." [GOC:TermGenie] +synonym: "activation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "activation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "activation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "activation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "activation of phosphorylation of RNA polymerase II C-terminal domain" NARROW [GOC:TermGenie] +synonym: "positive regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "positive regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "positive regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "positive regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "up regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "up-regulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up-regulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up-regulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "upregulation of CTD domain phosphorylation of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "upregulation of generation of hyperphosphorylated CTD of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "upregulation of generation of II(0) form of RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "upregulation of hyperphosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphorylation of RNA polymerase II C-terminal domain" EXACT [GOC:TermGenie] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:1901407 ! regulation of phosphorylation of RNA polymerase II C-terminal domain +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +relationship: positively_regulates GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +created_by: vw +creation_date: 2012-10-01T14:41:15Z + +[Term] +id: GO:1901410 +name: regulation of tetrapyrrole biosynthetic process from glutamate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +is_a: GO:2000211 ! regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +relationship: regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +created_by: tt +creation_date: 2012-10-01T16:20:56Z + +[Term] +id: GO:1901411 +name: negative regulation of tetrapyrrole biosynthetic process from glutamate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthetic process from glutamate" NARROW [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +is_a: GO:1901410 ! regulation of tetrapyrrole biosynthetic process from glutamate +is_a: GO:1901464 ! negative regulation of tetrapyrrole biosynthetic process +is_a: GO:2000212 ! negative regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +relationship: negatively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +created_by: tt +creation_date: 2012-10-01T16:22:03Z + +[Term] +id: GO:1901412 +name: positive regulation of tetrapyrrole biosynthetic process from glutamate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthetic process from glutamate" NARROW [GOC:TermGenie] +synonym: "activation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole anabolism from glutamate" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthesis from glutamate" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthetic process from glutamate" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole formation from glutamate" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole synthesis from glutamate" EXACT [GOC:TermGenie] +is_a: GO:1901410 ! regulation of tetrapyrrole biosynthetic process from glutamate +is_a: GO:1901465 ! positive regulation of tetrapyrrole biosynthetic process +is_a: GO:2000213 ! positive regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +relationship: positively_regulates GO:0033526 ! tetrapyrrole biosynthetic process from glutamate +created_by: tt +creation_date: 2012-10-01T16:22:21Z + +[Term] +id: GO:1901413 +name: regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +relationship: regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +created_by: tt +creation_date: 2012-10-01T16:27:43Z + +[Term] +id: GO:1901414 +name: negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" NARROW [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:1900543 ! negative regulation of purine nucleotide metabolic process +is_a: GO:1901413 ! regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA +is_a: GO:1901464 ! negative regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +relationship: negatively_regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +created_by: tt +creation_date: 2012-10-01T16:28:54Z + +[Term] +id: GO:1901415 +name: positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" NARROW [GOC:TermGenie] +synonym: "activation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole anabolism from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole formation from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA" EXACT [GOC:TermGenie] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:1900544 ! positive regulation of purine nucleotide metabolic process +is_a: GO:1901413 ! regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA +is_a: GO:1901465 ! positive regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +relationship: positively_regulates GO:0033527 ! tetrapyrrole biosynthetic process from glycine and succinyl-CoA +created_by: tt +creation_date: 2012-10-01T16:29:12Z + +[Term] +id: GO:1901416 +name: regulation of response to ethanol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to ethanol." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1901419 ! regulation of response to alcohol +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045471 ! response to ethanol +relationship: regulates GO:0045471 ! response to ethanol +created_by: tt +creation_date: 2012-10-01T16:48:24Z + +[Term] +id: GO:1901417 +name: negative regulation of response to ethanol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to ethanol" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to ethanol" EXACT [GOC:TermGenie] +synonym: "downregulation of response to ethanol" EXACT [GOC:TermGenie] +synonym: "inhibition of response to ethanol" NARROW [GOC:TermGenie] +is_a: GO:1901416 ! regulation of response to ethanol +is_a: GO:1901420 ! negative regulation of response to alcohol +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045471 ! response to ethanol +relationship: negatively_regulates GO:0045471 ! response to ethanol +created_by: tt +creation_date: 2012-10-01T16:49:33Z + +[Term] +id: GO:1901418 +name: positive regulation of response to ethanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to ethanol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to ethanol" NARROW [GOC:TermGenie] +synonym: "up regulation of response to ethanol" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to ethanol" EXACT [GOC:TermGenie] +synonym: "upregulation of response to ethanol" EXACT [GOC:TermGenie] +is_a: GO:1901416 ! regulation of response to ethanol +is_a: GO:1901421 ! positive regulation of response to alcohol +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045471 ! response to ethanol +relationship: positively_regulates GO:0045471 ! response to ethanol +created_by: tt +creation_date: 2012-10-01T16:49:51Z + +[Term] +id: GO:1901419 +name: regulation of response to alcohol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097305 ! response to alcohol +relationship: regulates GO:0097305 ! response to alcohol +created_by: tt +creation_date: 2012-10-01T16:52:13Z + +[Term] +id: GO:1901420 +name: negative regulation of response to alcohol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to alcohol" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to alcohol" EXACT [GOC:TermGenie] +synonym: "downregulation of response to alcohol" EXACT [GOC:TermGenie] +synonym: "inhibition of response to alcohol" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901419 ! regulation of response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097305 ! response to alcohol +relationship: negatively_regulates GO:0097305 ! response to alcohol +created_by: tt +creation_date: 2012-10-01T16:53:25Z + +[Term] +id: GO:1901421 +name: positive regulation of response to alcohol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to alcohol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to alcohol" NARROW [GOC:TermGenie] +synonym: "up regulation of response to alcohol" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to alcohol" EXACT [GOC:TermGenie] +synonym: "upregulation of response to alcohol" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901419 ! regulation of response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097305 ! response to alcohol +relationship: positively_regulates GO:0097305 ! response to alcohol +created_by: tt +creation_date: 2012-10-01T16:53:42Z + +[Term] +id: GO:1901422 +name: response to butan-1-ol +namespace: biological_process +alt_id: GO:1990336 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus." [GOC:mengo_curators, GOC:TermGenie, PMID:24014527] +synonym: "process resulting in tolerance to butan-1-ol" NARROW [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0097305 ! response to alcohol + +[Term] +id: GO:1901423 +name: response to benzene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +created_by: tt +creation_date: 2012-10-01T18:35:11Z + +[Term] +id: GO:1901424 +name: response to toluene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +created_by: tt +creation_date: 2012-10-01T18:38:32Z + +[Term] +id: GO:1901425 +name: response to formic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010033 ! response to organic substance +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: tt +creation_date: 2012-10-01T18:43:05Z + +[Term] +id: GO:1901426 +name: response to furfural +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: tt +creation_date: 2012-10-01T18:45:43Z + +[Term] +id: GO:1901427 +name: response to propan-1-ol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0097305 ! response to alcohol +created_by: tt +creation_date: 2012-10-01T18:55:48Z + +[Term] +id: GO:1901428 +name: regulation of syringal lignin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process." [GOC:TermGenie] +synonym: "regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901141 ! regulation of lignin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901066 ! syringal lignin biosynthetic process +relationship: regulates GO:1901066 ! syringal lignin biosynthetic process +created_by: tb +creation_date: 2012-10-01T20:13:41Z + +[Term] +id: GO:1901429 +name: negative regulation of syringal lignin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1901428 ! regulation of syringal lignin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901066 ! syringal lignin biosynthetic process +relationship: negatively_regulates GO:1901066 ! syringal lignin biosynthetic process +created_by: tb +creation_date: 2012-10-01T20:14:51Z + +[Term] +id: GO:1901430 +name: positive regulation of syringal lignin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process." [GOC:TermGenie] +synonym: "activation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of S-lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1901428 ! regulation of syringal lignin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901066 ! syringal lignin biosynthetic process +relationship: positively_regulates GO:1901066 ! syringal lignin biosynthetic process +created_by: tb +creation_date: 2012-10-01T20:15:09Z + +[Term] +id: GO:1901431 +name: regulation of response to cycloalkane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to cycloalkane." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014071 ! response to cycloalkane +relationship: regulates GO:0014071 ! response to cycloalkane +created_by: tt +creation_date: 2012-10-01T21:01:58Z + +[Term] +id: GO:1901432 +name: negative regulation of response to cycloalkane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to cycloalkane" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to cycloalkane" EXACT [GOC:TermGenie] +synonym: "downregulation of response to cycloalkane" EXACT [GOC:TermGenie] +synonym: "inhibition of response to cycloalkane" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901431 ! regulation of response to cycloalkane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014071 ! response to cycloalkane +relationship: negatively_regulates GO:0014071 ! response to cycloalkane +created_by: tt +creation_date: 2012-10-01T21:03:08Z + +[Term] +id: GO:1901433 +name: positive regulation of response to cycloalkane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to cycloalkane." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to cycloalkane" NARROW [GOC:TermGenie] +synonym: "up regulation of response to cycloalkane" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to cycloalkane" EXACT [GOC:TermGenie] +synonym: "upregulation of response to cycloalkane" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901431 ! regulation of response to cycloalkane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014071 ! response to cycloalkane +relationship: positively_regulates GO:0014071 ! response to cycloalkane +created_by: tt +creation_date: 2012-10-01T21:03:26Z + +[Term] +id: GO:1901434 +name: regulation of toluene catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of toluene catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of toluene degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:1901437 ! regulation of toluene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042203 ! toluene catabolic process +relationship: regulates GO:0042203 ! toluene catabolic process +created_by: tt +creation_date: 2012-10-01T21:12:31Z + +[Term] +id: GO:1901435 +name: negative regulation of toluene catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of toluene catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of toluene degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of toluene degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901434 ! regulation of toluene catabolic process +is_a: GO:1901438 ! negative regulation of toluene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042203 ! toluene catabolic process +relationship: negatively_regulates GO:0042203 ! toluene catabolic process +created_by: tt +creation_date: 2012-10-01T21:13:41Z + +[Term] +id: GO:1901436 +name: positive regulation of toluene catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of toluene catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "activation of toluene catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "activation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901434 ! regulation of toluene catabolic process +is_a: GO:1901439 ! positive regulation of toluene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042203 ! toluene catabolic process +relationship: positively_regulates GO:0042203 ! toluene catabolic process +created_by: tt +creation_date: 2012-10-01T21:13:57Z + +[Term] +id: GO:1901437 +name: regulation of toluene metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of toluene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of toluene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018970 ! toluene metabolic process +relationship: regulates GO:0018970 ! toluene metabolic process +created_by: tt +creation_date: 2012-10-01T21:17:41Z + +[Term] +id: GO:1901438 +name: negative regulation of toluene metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of toluene metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of toluene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1901437 ! regulation of toluene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018970 ! toluene metabolic process +relationship: negatively_regulates GO:0018970 ! toluene metabolic process +created_by: tt +creation_date: 2012-10-01T21:18:50Z + +[Term] +id: GO:1901439 +name: positive regulation of toluene metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of toluene metabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "activation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "activation of toluene metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of toluene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of methylbenzene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methylbenzene metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of toluene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1901437 ! regulation of toluene metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018970 ! toluene metabolic process +relationship: positively_regulates GO:0018970 ! toluene metabolic process +created_by: tt +creation_date: 2012-10-01T21:19:08Z + +[Term] +id: GO:1901440 +name: poly(hydroxyalkanoate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(hydroxyalkanoate)." [GOC:mengo_curators, GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: tt +creation_date: 2012-10-02T01:47:26Z + +[Term] +id: GO:1901441 +name: poly(hydroxyalkanoate) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate)." [GOC:mengo_curators, GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) anabolism" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) formation" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901440 ! poly(hydroxyalkanoate) metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: tt +creation_date: 2012-10-02T01:48:33Z + +[Term] +id: GO:1901442 +name: regulation of response to furfural +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to furfural." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901426 ! response to furfural +relationship: regulates GO:1901426 ! response to furfural +created_by: tt +creation_date: 2012-10-02T14:09:26Z + +[Term] +id: GO:1901443 +name: negative regulation of response to furfural +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to furfural" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to furfural" EXACT [GOC:TermGenie] +synonym: "downregulation of response to furfural" EXACT [GOC:TermGenie] +synonym: "inhibition of response to furfural" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901442 ! regulation of response to furfural +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901426 ! response to furfural +relationship: negatively_regulates GO:1901426 ! response to furfural +created_by: tt +creation_date: 2012-10-02T14:10:34Z + +[Term] +id: GO:1901444 +name: positive regulation of response to furfural +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to furfural." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to furfural" NARROW [GOC:TermGenie] +synonym: "up regulation of response to furfural" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to furfural" EXACT [GOC:TermGenie] +synonym: "upregulation of response to furfural" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901442 ! regulation of response to furfural +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901426 ! response to furfural +relationship: positively_regulates GO:1901426 ! response to furfural +created_by: tt +creation_date: 2012-10-02T14:10:51Z + +[Term] +id: GO:1901445 +name: regulation of response to propan-1-ol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to propan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1901419 ! regulation of response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901427 ! response to propan-1-ol +relationship: regulates GO:1901427 ! response to propan-1-ol +created_by: tt +creation_date: 2012-10-02T14:12:46Z + +[Term] +id: GO:1901446 +name: negative regulation of response to propan-1-ol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to propan-1-ol" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to propan-1-ol" EXACT [GOC:TermGenie] +synonym: "downregulation of response to propan-1-ol" EXACT [GOC:TermGenie] +synonym: "inhibition of response to propan-1-ol" NARROW [GOC:TermGenie] +is_a: GO:1901420 ! negative regulation of response to alcohol +is_a: GO:1901445 ! regulation of response to propan-1-ol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901427 ! response to propan-1-ol +relationship: negatively_regulates GO:1901427 ! response to propan-1-ol +created_by: tt +creation_date: 2012-10-02T14:13:52Z + +[Term] +id: GO:1901447 +name: positive regulation of response to propan-1-ol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to propan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to propan-1-ol" NARROW [GOC:TermGenie] +synonym: "up regulation of response to propan-1-ol" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to propan-1-ol" EXACT [GOC:TermGenie] +synonym: "upregulation of response to propan-1-ol" EXACT [GOC:TermGenie] +is_a: GO:1901421 ! positive regulation of response to alcohol +is_a: GO:1901445 ! regulation of response to propan-1-ol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901427 ! response to propan-1-ol +relationship: positively_regulates GO:1901427 ! response to propan-1-ol +created_by: tt +creation_date: 2012-10-02T14:14:10Z + +[Term] +id: GO:1901448 +name: regulation of response to butan-1-ol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to butan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1901419 ! regulation of response to alcohol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901422 ! response to butan-1-ol +relationship: regulates GO:1901422 ! response to butan-1-ol +created_by: tt +creation_date: 2012-10-02T14:15:50Z + +[Term] +id: GO:1901449 +name: negative regulation of response to butan-1-ol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "downregulation of response to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "inhibition of response to butan-1-ol" NARROW [GOC:TermGenie] +is_a: GO:1901420 ! negative regulation of response to alcohol +is_a: GO:1901448 ! regulation of response to butan-1-ol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901422 ! response to butan-1-ol +relationship: negatively_regulates GO:1901422 ! response to butan-1-ol +created_by: tt +creation_date: 2012-10-02T14:16:59Z + +[Term] +id: GO:1901450 +name: positive regulation of response to butan-1-ol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to butan-1-ol." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to butan-1-ol" NARROW [GOC:TermGenie] +synonym: "up regulation of response to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "upregulation of response to butan-1-ol" EXACT [GOC:TermGenie] +is_a: GO:1901421 ! positive regulation of response to alcohol +is_a: GO:1901448 ! regulation of response to butan-1-ol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901422 ! response to butan-1-ol +relationship: positively_regulates GO:1901422 ! response to butan-1-ol +created_by: tt +creation_date: 2012-10-02T14:17:17Z + +[Term] +id: GO:1901451 +name: regulation of response to benzene +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to benzene." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901423 ! response to benzene +relationship: regulates GO:1901423 ! response to benzene +created_by: tt +creation_date: 2012-10-02T14:19:10Z + +[Term] +id: GO:1901452 +name: negative regulation of response to benzene +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to benzene" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to benzene" EXACT [GOC:TermGenie] +synonym: "downregulation of response to benzene" EXACT [GOC:TermGenie] +synonym: "inhibition of response to benzene" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901451 ! regulation of response to benzene +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901423 ! response to benzene +relationship: negatively_regulates GO:1901423 ! response to benzene +created_by: tt +creation_date: 2012-10-02T14:20:23Z + +[Term] +id: GO:1901453 +name: positive regulation of response to benzene +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to benzene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to benzene" NARROW [GOC:TermGenie] +synonym: "up regulation of response to benzene" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to benzene" EXACT [GOC:TermGenie] +synonym: "upregulation of response to benzene" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901451 ! regulation of response to benzene +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901423 ! response to benzene +relationship: positively_regulates GO:1901423 ! response to benzene +created_by: tt +creation_date: 2012-10-02T14:20:41Z + +[Term] +id: GO:1901454 +name: regulation of response to toluene +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to toluene." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901424 ! response to toluene +relationship: regulates GO:1901424 ! response to toluene +created_by: tt +creation_date: 2012-10-02T14:22:17Z + +[Term] +id: GO:1901455 +name: negative regulation of response to toluene +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to toluene" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to toluene" EXACT [GOC:TermGenie] +synonym: "downregulation of response to toluene" EXACT [GOC:TermGenie] +synonym: "inhibition of response to toluene" NARROW [GOC:TermGenie] +is_a: GO:1901454 ! regulation of response to toluene +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901424 ! response to toluene +relationship: negatively_regulates GO:1901424 ! response to toluene +created_by: tt +creation_date: 2012-10-02T14:23:28Z + +[Term] +id: GO:1901456 +name: positive regulation of response to toluene +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to toluene." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to toluene" NARROW [GOC:TermGenie] +synonym: "up regulation of response to toluene" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to toluene" EXACT [GOC:TermGenie] +synonym: "upregulation of response to toluene" EXACT [GOC:TermGenie] +is_a: GO:1901454 ! regulation of response to toluene +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901424 ! response to toluene +relationship: positively_regulates GO:1901424 ! response to toluene +created_by: tt +creation_date: 2012-10-02T14:23:45Z + +[Term] +id: GO:1901457 +name: regulation of response to acetate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010034 ! response to acetate +relationship: regulates GO:0010034 ! response to acetate +created_by: tt +creation_date: 2012-10-02T14:25:06Z + +[Term] +id: GO:1901458 +name: negative regulation of response to acetate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] +synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] +synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1901457 ! regulation of response to acetate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010034 ! response to acetate +relationship: negatively_regulates GO:0010034 ! response to acetate +created_by: tt +creation_date: 2012-10-02T14:26:15Z + +[Term] +id: GO:1901459 +name: positive regulation of response to acetate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to acetate" NARROW [GOC:TermGenie] +synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] +synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901457 ! regulation of response to acetate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010034 ! response to acetate +relationship: positively_regulates GO:0010034 ! response to acetate +created_by: tt +creation_date: 2012-10-02T14:26:34Z + +[Term] +id: GO:1901460 +name: regulation of response to formic acid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901425 ! response to formic acid +relationship: regulates GO:1901425 ! response to formic acid +created_by: tt +creation_date: 2012-10-02T14:27:54Z + +[Term] +id: GO:1901461 +name: negative regulation of response to formic acid +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of response to formic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to formic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of response to formic acid" EXACT [GOC:TermGenie] +synonym: "inhibition of response to formic acid" NARROW [GOC:TermGenie] +is_a: GO:1901460 ! regulation of response to formic acid +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901425 ! response to formic acid +relationship: negatively_regulates GO:1901425 ! response to formic acid +created_by: tt +creation_date: 2012-10-02T14:29:02Z + +[Term] +id: GO:1901462 +name: positive regulation of response to formic acid +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to formic acid." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of response to formic acid" NARROW [GOC:TermGenie] +synonym: "up regulation of response to formic acid" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to formic acid" EXACT [GOC:TermGenie] +synonym: "upregulation of response to formic acid" EXACT [GOC:TermGenie] +is_a: GO:1901460 ! regulation of response to formic acid +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901425 ! response to formic acid +relationship: positively_regulates GO:1901425 ! response to formic acid +created_by: tt +creation_date: 2012-10-02T14:29:20Z + +[Term] +id: GO:1901463 +name: regulation of tetrapyrrole biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033014 ! tetrapyrrole biosynthetic process +relationship: regulates GO:0033014 ! tetrapyrrole biosynthetic process +created_by: tt +creation_date: 2012-10-02T14:34:14Z + +[Term] +id: GO:1901464 +name: negative regulation of tetrapyrrole biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process +relationship: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process +created_by: tt +creation_date: 2012-10-02T14:35:26Z + +[Term] +id: GO:1901465 +name: positive regulation of tetrapyrrole biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process +is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process +relationship: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process +created_by: tt +creation_date: 2012-10-02T14:35:43Z + +[Term] +id: GO:1901466 +name: regulation of ferulate catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferulate catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ferulate degradation" EXACT [GOC:TermGenie] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901067 ! ferulate catabolic process +relationship: regulates GO:1901067 ! ferulate catabolic process +created_by: tt +creation_date: 2012-10-02T14:37:29Z + +[Term] +id: GO:1901467 +name: negative regulation of ferulate catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of ferulate catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferulate degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1901466 ! regulation of ferulate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901067 ! ferulate catabolic process +relationship: negatively_regulates GO:1901067 ! ferulate catabolic process +created_by: tt +creation_date: 2012-10-02T14:38:38Z + +[Term] +id: GO:1901468 +name: positive regulation of ferulate catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ferulate catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "activation of ferulate catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "activation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferulate degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of ferulate breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of ferulate catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ferulate catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ferulate degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1901466 ! regulation of ferulate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901067 ! ferulate catabolic process +relationship: positively_regulates GO:1901067 ! ferulate catabolic process +created_by: tt +creation_date: 2012-10-02T14:38:56Z + +[Term] +id: GO:1901469 +name: regulation of syringal lignin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of syringal lignin catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:2000762 ! regulation of phenylpropanoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901065 ! syringal lignin catabolic process +relationship: regulates GO:1901065 ! syringal lignin catabolic process +created_by: tt +creation_date: 2012-10-02T14:41:12Z + +[Term] +id: GO:1901470 +name: negative regulation of syringal lignin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "down regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:1901469 ! regulation of syringal lignin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901065 ! syringal lignin catabolic process +relationship: negatively_regulates GO:1901065 ! syringal lignin catabolic process +created_by: tt +creation_date: 2012-10-02T14:42:21Z + +[Term] +id: GO:1901471 +name: positive regulation of syringal lignin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process." [GOC:mengo_curators, GOC:TermGenie] +synonym: "activation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "activation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of syringal lignin degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of S-lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of syringal lignin degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:1901469 ! regulation of syringal lignin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901065 ! syringal lignin catabolic process +relationship: positively_regulates GO:1901065 ! syringal lignin catabolic process +created_by: tt +creation_date: 2012-10-02T14:42:39Z + +[Term] +id: GO:1901472 +name: regulation of Golgi calcium ion export +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Golgi calcium ion export." [GOC:TermGenie] +is_a: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061454 ! release of sequestered calcium ion into cytosol by Golgi +relationship: regulates GO:0061454 ! release of sequestered calcium ion into cytosol by Golgi +created_by: al +creation_date: 2012-10-03T07:26:03Z + +[Term] +id: GO:1901474 +name: azole transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0045118 +def: "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other." [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole] +synonym: "azole transporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:0045117 ! azole transmembrane transport +created_by: tb +creation_date: 2012-10-04T20:00:27Z + +[Term] +id: GO:1901475 +name: pyruvate transmembrane transport +namespace: biological_process +def: "The directed movement of pyruvate across a membrane." [GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "pyruvate membrane transport" EXACT [] +is_a: GO:0006848 ! pyruvate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: tb +creation_date: 2012-10-04T20:52:54Z + +[Term] +id: GO:1901477 +name: benomyl transmembrane transport +namespace: biological_process +def: "The directed movement of benomyl across a membrane." [GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "benomyl membrane transport" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015900 ! benomyl transport +created_by: tb +creation_date: 2012-10-04T23:11:36Z + +[Term] +id: GO:1901478 +name: aminotriazole transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015241 +def: "Enables the transfer of amitrole from one side of a membrane to the other." [GOC:TermGenie] +synonym: "aminotriazole transporter activity" BROAD [] +is_a: GO:1901474 ! azole transmembrane transporter activity +created_by: tb +creation_date: 2012-10-04T23:21:06Z + +[Term] +id: GO:1901479 +name: benomyl transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015242 +def: "Enables the transfer of benomyl from one side of a membrane to the other." [GOC:TermGenie] +synonym: "benomyl transporter activity" RELATED [] +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0042910 ! xenobiotic transmembrane transporter activity +relationship: part_of GO:1901477 ! benomyl transmembrane transport +created_by: tb +creation_date: 2012-10-04T23:21:10Z + +[Term] +id: GO:1901480 +name: oleate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of oleate from one side of a membrane to the other." [GOC:TermGenie, PMID:19493158, RHEA:33655] +synonym: "oleate transporter activity" RELATED [] +is_a: GO:0005324 ! long-chain fatty acid transporter activity +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +created_by: ab +creation_date: 2012-10-07T17:11:56Z + +[Term] +id: GO:1901481 +name: L-glutamate import involved in cellular response to nitrogen starvation +namespace: biological_process +def: "Any L-glutamate import that is involved in cellular response to nitrogen starvation." [GOC:TermGenie] +synonym: "L-glutamate uptake involved in cellular response to nitrogen starvation" EXACT [GOC:TermGenie] +is_a: GO:0051938 ! L-glutamate import +intersection_of: GO:0051938 ! L-glutamate import +intersection_of: part_of GO:0006995 ! cellular response to nitrogen starvation +relationship: part_of GO:0006995 ! cellular response to nitrogen starvation +created_by: al +creation_date: 2012-10-08T08:32:29Z + +[Term] +id: GO:1901482 +name: L-lysine import into vacuole involved in cellular response to nitrogen starvation +namespace: biological_process +def: "A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation." [GOC:TermGenie] +is_a: GO:0090517 ! L-lysine transmembrane import into vacuole +relationship: part_of GO:0006995 ! cellular response to nitrogen starvation +created_by: al +creation_date: 2012-10-08T08:34:03Z + +[Term] +id: GO:1901483 +name: regulation of transcription factor catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription factor catabolic process." [GOC:al, GOC:TermGenie, GOC:vw, PMID:22833559] +synonym: "regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of transcription factor degradation" EXACT [GOC:TermGenie] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036369 ! transcription factor catabolic process +relationship: regulates GO:0036369 ! transcription factor catabolic process +created_by: bf +creation_date: 2012-10-08T09:03:18Z + +[Term] +id: GO:1901484 +name: negative regulation of transcription factor catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process." [GOC:al, GOC:TermGenie, GOC:vw] +synonym: "down regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription factor catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription factor degradation" EXACT [GOC:TermGenie] +is_a: GO:0032435 ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1901483 ! regulation of transcription factor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036369 ! transcription factor catabolic process +relationship: negatively_regulates GO:0036369 ! transcription factor catabolic process +created_by: bf +creation_date: 2012-10-08T09:03:22Z + +[Term] +id: GO:1901485 +name: positive regulation of transcription factor catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process." [GOC:al, GOC:TermGenie, GOC:vw, PMID:22833559] +synonym: "activation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "activation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "activation of transcription factor catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "activation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription factor degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasome-mediated transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of sequence-specific DNA binding transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription factor breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription factor catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription factor degradation" EXACT [GOC:TermGenie] +is_a: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1901483 ! regulation of transcription factor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036369 ! transcription factor catabolic process +relationship: positively_regulates GO:0036369 ! transcription factor catabolic process +created_by: bf +creation_date: 2012-10-08T09:03:27Z + +[Term] +id: GO:1901486 +name: obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process +namespace: biological_process +def: "OBSOLETE. Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway." [GOC:TermGenie, GOC:vw, PMID:22833559] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +synonym: "negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation" NARROW [GOC:bf] +synonym: "negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolism" EXACT [GOC:bf] +synonym: "negative regulation of SREBP-mediated signaling pathway by positive regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signalling pathway by positive regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2012-10-09T08:23:26Z + +[Term] +id: GO:1901487 +name: obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels +namespace: biological_process +def: "OBSOLETE. Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway." [GOC:TermGenie, GOC:vw, PMID:22833559] +comment: The reason for obsoletion is that this is better captured in a GO-CAM model. +synonym: "negative regulation of SREBP signaling by acceleration of SREBP degradation, in response to increased oxygen levels" NARROW [PMID:22833559] +synonym: "negative regulation of SREBP signaling by positive regulation of transcription factor catabolism in response to increased oxygen levels" EXACT [GOC:bf] +synonym: "negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation, in response to elevated oxygen" NARROW [GOC:bf] +synonym: "negative regulation of SREBP-mediated signaling pathway in presence of oxygen by positive regulation of transcription factor catabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels by positive regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14544 xsd:anyURI +is_obsolete: true +created_by: bf +creation_date: 2012-10-09T08:23:33Z + +[Term] +id: GO:1901488 +name: obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process +namespace: biological_process +def: "OBSOLETE. Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway." [GOC:TermGenie, GOC:vw, PMID:22833559] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +synonym: "positive regulation of SREBP signaling pathway by inhibition of SREBP degradation" NARROW [PMID:22833559] +synonym: "positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation" NARROW [PMID:22833559] +synonym: "positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolism" EXACT [GOC:bf] +synonym: "positive regulation of SREBP-mediated signaling pathway by negative regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of SREBP-mediated signalling pathway by negative regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2012-10-09T08:23:43Z + +[Term] +id: GO:1901489 +name: obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels +namespace: biological_process +def: "OBSOLETE. Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway." [GOC:TermGenie, GOC:vw, PMID:22833559] +comment: The reason for obsoletion is that this term should be represented by a GO-CAM model. +synonym: "positive regulation of SREBP signaling by inhibition of SREBP degradation in response to decreased oxygen levels" EXACT [GOC:bf] +synonym: "positive regulation of SREBP signaling by negative regulation of transcription factor catabolism at low oxygen levels" EXACT [GOC:bf] +synonym: "positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation, in response to decreased oxygen" NARROW [PMID:22833559] +synonym: "positive regulation of SREBP-mediated signaling pathway in absence of oxygen by negative regulation of transcription factor catabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels by negative regulation of transcription factor catabolic process" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2012-10-09T08:23:50Z + +[Term] +id: GO:1901490 +name: regulation of lymphangiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphangiogenesis." [GOC:dph, GOC:TermGenie, PMID:20133819] +synonym: "regulation of lymph vessel formation" EXACT [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001946 ! lymphangiogenesis +relationship: regulates GO:0001946 ! lymphangiogenesis +created_by: dph +creation_date: 2012-10-15T13:08:17Z + +[Term] +id: GO:1901491 +name: negative regulation of lymphangiogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis." [GOC:dph, GOC:TermGenie, PMID:20133819] +synonym: "down regulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "down regulation of lymphangiogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lymphangiogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "downregulation of lymphangiogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of lymph vessel formation" NARROW [GOC:TermGenie] +synonym: "inhibition of lymphangiogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of lymph vessel formation" EXACT [GOC:TermGenie] +is_a: GO:1901343 ! negative regulation of vasculature development +is_a: GO:1901490 ! regulation of lymphangiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001946 ! lymphangiogenesis +relationship: negatively_regulates GO:0001946 ! lymphangiogenesis +created_by: dph +creation_date: 2012-10-15T13:08:21Z + +[Term] +id: GO:1901492 +name: positive regulation of lymphangiogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphangiogenesis." [GOC:dph, GOC:TermGenie, PMID:20133819] +synonym: "activation of lymph vessel formation" NARROW [GOC:TermGenie] +synonym: "activation of lymphangiogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "up regulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "up regulation of lymphangiogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lymphangiogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of lymph vessel formation" EXACT [GOC:TermGenie] +synonym: "upregulation of lymphangiogenesis" EXACT [GOC:TermGenie] +is_a: GO:1901490 ! regulation of lymphangiogenesis +is_a: GO:1904018 ! positive regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001946 ! lymphangiogenesis +relationship: positively_regulates GO:0001946 ! lymphangiogenesis +created_by: dph +creation_date: 2012-10-15T13:08:25Z + +[Term] +id: GO:1901493 +name: response to decalin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +created_by: tt +creation_date: 2012-10-16T13:41:09Z + +[Term] +id: GO:1901494 +name: regulation of cysteine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cysteine metabolic process." [GOC:TermGenie] +synonym: "regulation of cysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031335 ! regulation of sulfur amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006534 ! cysteine metabolic process +relationship: regulates GO:0006534 ! cysteine metabolic process +created_by: vw +creation_date: 2012-10-16T14:28:42Z + +[Term] +id: GO:1901495 +name: negative regulation of cysteine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process." [GOC:TermGenie] +synonym: "down regulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of cysteine metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of cysteine metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of cysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031336 ! negative regulation of sulfur amino acid metabolic process +is_a: GO:1901494 ! regulation of cysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006534 ! cysteine metabolic process +relationship: negatively_regulates GO:0006534 ! cysteine metabolic process +created_by: vw +creation_date: 2012-10-16T14:28:47Z + +[Term] +id: GO:1901496 +name: positive regulation of cysteine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cysteine metabolic process." [GOC:TermGenie] +synonym: "activation of cysteine metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of cysteine metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cysteine metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of cysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031337 ! positive regulation of sulfur amino acid metabolic process +is_a: GO:1901494 ! regulation of cysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006534 ! cysteine metabolic process +relationship: positively_regulates GO:0006534 ! cysteine metabolic process +created_by: vw +creation_date: 2012-10-16T14:28:51Z + +[Term] +id: GO:1901497 +name: response to diphenyl ether +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +created_by: tt +creation_date: 2012-10-16T14:58:08Z + +[Term] +id: GO:1901498 +name: response to tetralin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +created_by: tt +creation_date: 2012-10-16T15:10:22Z + +[Term] +id: GO:1901499 +name: response to hexane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2012-10-16T15:14:49Z + +[Term] +id: GO:1901500 +name: response to p-xylene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:1901501 ! response to xylene +created_by: tt +creation_date: 2012-10-16T15:23:54Z + +[Term] +id: GO:1901501 +name: response to xylene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus." [GOC:mengo_curators, GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +created_by: tt +creation_date: 2012-10-16T15:25:47Z + +[Term] +id: GO:1901502 +name: ether catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ether." [GOC:pr, GOC:TermGenie] +synonym: "ether breakdown" EXACT [GOC:TermGenie] +synonym: "ether catabolism" EXACT [GOC:TermGenie] +synonym: "ether degradation" EXACT [GOC:TermGenie] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: pr +creation_date: 2012-10-17T09:42:43Z + +[Term] +id: GO:1901503 +name: ether biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ether." [GOC:pr, GOC:TermGenie] +synonym: "ether anabolism" EXACT [GOC:TermGenie] +synonym: "ether biosynthesis" EXACT [GOC:TermGenie] +synonym: "ether formation" EXACT [GOC:TermGenie] +synonym: "ether synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: pr +creation_date: 2012-10-17T09:42:47Z + +[Term] +id: GO:1901504 +name: triazole transport +namespace: biological_process +def: "The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:pr, GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: pr +creation_date: 2012-10-17T09:47:46Z + +[Term] +id: GO:1901505 +name: carbohydrate derivative transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +synonym: "carbohydrate derivative transporter activity" RELATED [] +is_a: GO:0022857 ! transmembrane transporter activity +relationship: part_of GO:1901264 ! carbohydrate derivative transport +created_by: pr +creation_date: 2012-10-17T10:31:22Z + +[Term] +id: GO:1901506 +name: regulation of acylglycerol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acylglycerol transport." [GOC:sart, GOC:TermGenie] +synonym: "regulation of glyceride transport" EXACT [GOC:TermGenie] +is_a: GO:0032368 ! regulation of lipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034196 ! acylglycerol transport +relationship: regulates GO:0034196 ! acylglycerol transport +created_by: sart +creation_date: 2012-10-17T11:06:10Z + +[Term] +id: GO:1901507 +name: negative regulation of acylglycerol transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport." [GOC:sart, GOC:TermGenie] +synonym: "down regulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "down regulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "downregulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "downregulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "inhibition of acylglycerol transport" NARROW [GOC:TermGenie] +synonym: "inhibition of glyceride transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of glyceride transport" EXACT [GOC:TermGenie] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:1901506 ! regulation of acylglycerol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034196 ! acylglycerol transport +relationship: negatively_regulates GO:0034196 ! acylglycerol transport +created_by: sart +creation_date: 2012-10-17T11:06:18Z + +[Term] +id: GO:1901508 +name: positive regulation of acylglycerol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of acylglycerol transport." [GOC:sart, GOC:TermGenie] +synonym: "activation of acylglycerol transport" NARROW [GOC:TermGenie] +synonym: "activation of glyceride transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "up regulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "up regulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of glyceride transport" EXACT [GOC:TermGenie] +synonym: "upregulation of acylglycerol transport" EXACT [GOC:TermGenie] +synonym: "upregulation of glyceride transport" EXACT [GOC:TermGenie] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:1901506 ! regulation of acylglycerol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034196 ! acylglycerol transport +relationship: positively_regulates GO:0034196 ! acylglycerol transport +created_by: sart +creation_date: 2012-10-17T11:06:23Z + +[Term] +id: GO:1901509 +name: regulation of endothelial tube morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie] +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061154 ! endothelial tube morphogenesis +relationship: regulates GO:0061154 ! endothelial tube morphogenesis +created_by: dph +creation_date: 2012-10-17T14:30:40Z + +[Term] +id: GO:1901510 +name: (-)-microperfuranone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-microperfuranone." [GOC:di, GOC:TermGenie] +synonym: "(-)-microperfuranone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018904 ! ether metabolic process +is_a: GO:1901334 ! lactone metabolic process +created_by: di +creation_date: 2012-10-18T06:54:10Z + +[Term] +id: GO:1901511 +name: (-)-microperfuranone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone." [GOC:di, GOC:TermGenie] +synonym: "(-)-microperfuranone breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-microperfuranone catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-microperfuranone degradation" EXACT [GOC:TermGenie] +is_a: GO:1901335 ! lactone catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901510 ! (-)-microperfuranone metabolic process +created_by: di +creation_date: 2012-10-18T06:54:14Z + +[Term] +id: GO:1901512 +name: (-)-microperfuranone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-microperfuranone." [GOC:di, GOC:TermGenie] +synonym: "(-)-microperfuranone anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-microperfuranone biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-microperfuranone formation" EXACT [GOC:TermGenie] +synonym: "(-)-microperfuranone synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901336 ! lactone biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901510 ! (-)-microperfuranone metabolic process +created_by: di +creation_date: 2012-10-18T06:54:18Z + +[Term] +id: GO:1901513 +name: lipo-chitin oligosaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other." [GOC:TermGenie] +is_a: GO:0022857 ! transmembrane transporter activity +created_by: jl +creation_date: 2012-10-18T11:52:51Z + +[Term] +id: GO:1901514 +name: ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out)." [GOC:TermGenie] +synonym: "lipo-chitin oligosaccharide transmembrane-transporting ATPase activity" RELATED [] +is_a: GO:0042626 ! ATPase-coupled transmembrane transporter activity +is_a: GO:1901513 ! lipo-chitin oligosaccharide transmembrane transporter activity +created_by: jl +creation_date: 2012-10-18T11:52:55Z + +[Term] +id: GO:1901515 +name: poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other." [GOC:TermGenie, PMID:15090514, PMID:18359807] +is_a: GO:0022857 ! transmembrane transporter activity +created_by: jl +creation_date: 2012-10-18T11:57:04Z + +[Term] +id: GO:1901516 +name: aspyridone A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aspyridone A." [GOC:di, GOC:TermGenie] +synonym: "aspyridone A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +created_by: di +creation_date: 2012-10-18T18:31:28Z + +[Term] +id: GO:1901517 +name: aspyridone A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aspyridone A." [GOC:di, GOC:TermGenie] +synonym: "aspyridone A breakdown" EXACT [GOC:TermGenie] +synonym: "aspyridone A catabolism" EXACT [GOC:TermGenie] +synonym: "aspyridone A degradation" EXACT [GOC:TermGenie] +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process +is_a: GO:1901516 ! aspyridone A metabolic process +created_by: di +creation_date: 2012-10-18T18:31:32Z + +[Term] +id: GO:1901518 +name: aspyridone A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aspyridone A." [GOC:di, GOC:TermGenie] +synonym: "aspyridone A anabolism" EXACT [GOC:TermGenie] +synonym: "aspyridone A biosynthesis" EXACT [GOC:TermGenie] +synonym: "aspyridone A formation" EXACT [GOC:TermGenie] +synonym: "aspyridone A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process +is_a: GO:1901516 ! aspyridone A metabolic process +created_by: di +creation_date: 2012-10-18T18:31:36Z + +[Term] +id: GO:1901519 +name: aspyridone B metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aspyridone B." [GOC:di, GOC:TermGenie] +synonym: "aspyridone B metabolism" EXACT [GOC:TermGenie] +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +created_by: di +creation_date: 2012-10-18T18:31:40Z + +[Term] +id: GO:1901520 +name: aspyridone B catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of aspyridone B." [GOC:di, GOC:TermGenie] +synonym: "aspyridone B breakdown" EXACT [GOC:TermGenie] +synonym: "aspyridone B catabolism" EXACT [GOC:TermGenie] +synonym: "aspyridone B degradation" EXACT [GOC:TermGenie] +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process +is_a: GO:1901519 ! aspyridone B metabolic process +created_by: di +creation_date: 2012-10-18T18:31:44Z + +[Term] +id: GO:1901521 +name: aspyridone B biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aspyridone B." [GOC:di, GOC:TermGenie] +synonym: "aspyridone B anabolism" EXACT [GOC:TermGenie] +synonym: "aspyridone B biosynthesis" EXACT [GOC:TermGenie] +synonym: "aspyridone B formation" EXACT [GOC:TermGenie] +synonym: "aspyridone B synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process +is_a: GO:1901519 ! aspyridone B metabolic process +created_by: di +creation_date: 2012-10-18T18:31:52Z + +[Term] +id: GO:1901522 +name: positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus." [GOC:TermGenie, PMID:22840777] +synonym: "activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0070887 ! cellular response to chemical stimulus +relationship: part_of GO:0070887 ! cellular response to chemical stimulus +created_by: al +creation_date: 2012-10-19T08:25:05Z + +[Term] +id: GO:1901523 +name: icosanoid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of icosanoid." [GOC:pr, GOC:TermGenie] +synonym: "icosanoid breakdown" EXACT [GOC:TermGenie] +synonym: "icosanoid catabolism" EXACT [GOC:TermGenie] +synonym: "icosanoid degradation" EXACT [GOC:TermGenie] +is_a: GO:0006690 ! icosanoid metabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:1901569 ! fatty acid derivative catabolic process +created_by: pr +creation_date: 2012-10-22T10:50:09Z + +[Term] +id: GO:1901524 +name: regulation of mitophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macromitophagy." [GOC:TermGenie] +synonym: "regulation of macromitophagy" EXACT [] +is_a: GO:0016241 ! regulation of macroautophagy +is_a: GO:1903146 ! regulation of autophagy of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000423 ! mitophagy +relationship: regulates GO:0000423 ! mitophagy +created_by: krc +creation_date: 2012-10-22T16:56:45Z + +[Term] +id: GO:1901525 +name: negative regulation of mitophagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy." [GOC:TermGenie] +synonym: "down regulation of macromitophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of macromitophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of macromitophagy" EXACT [GOC:TermGenie] +synonym: "inhibition of macromitophagy" NARROW [GOC:TermGenie] +synonym: "negative regulation of macromitophagy" EXACT [] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:1901524 ! regulation of mitophagy +is_a: GO:1903147 ! negative regulation of autophagy of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000423 ! mitophagy +relationship: negatively_regulates GO:0000423 ! mitophagy +created_by: krc +creation_date: 2012-10-22T16:56:49Z + +[Term] +id: GO:1901526 +name: positive regulation of mitophagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitophagy." [GOC:TermGenie] +synonym: "activation of macromitophagy" NARROW [GOC:TermGenie] +synonym: "positive regulation of macromitophagy" EXACT [] +synonym: "up regulation of macromitophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of macromitophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of macromitophagy" EXACT [GOC:TermGenie] +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:1901524 ! regulation of mitophagy +is_a: GO:1903599 ! positive regulation of autophagy of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000423 ! mitophagy +relationship: positively_regulates GO:0000423 ! mitophagy +created_by: krc +creation_date: 2012-10-22T16:56:57Z + +[Term] +id: GO:1901527 +name: abscisic acid-activated signaling pathway involved in stomatal movement +namespace: biological_process +def: "Any abscisic acid mediated signaling pathway that is involved in stomatal movement." [GOC:TermGenie, PMID:22730405] +synonym: "abscisic acid mediated signaling pathway involved in stomatal movement" RELATED [] +synonym: "abscisic acid mediated signalling involved in stomatal movement" EXACT [GOC:TermGenie] +is_a: GO:0009738 ! abscisic acid-activated signaling pathway +intersection_of: GO:0009738 ! abscisic acid-activated signaling pathway +intersection_of: part_of GO:0010118 ! stomatal movement +relationship: part_of GO:0010118 ! stomatal movement +created_by: tb +creation_date: 2012-10-23T23:09:34Z + +[Term] +id: GO:1901528 +name: hydrogen peroxide mediated signaling pathway involved in stomatal movement +namespace: biological_process +def: "Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement." [GOC:TermGenie] +synonym: "H2O2 mediated signaling pathway involved in stomatal movement" EXACT [GOC:TermGenie] +synonym: "hydrogen peroxide mediated signalling pathway involved in stomatal movement" EXACT [GOC:TermGenie] +is_a: GO:0071588 ! hydrogen peroxide mediated signaling pathway +intersection_of: GO:0071588 ! hydrogen peroxide mediated signaling pathway +intersection_of: part_of GO:0010118 ! stomatal movement +relationship: part_of GO:0010118 ! stomatal movement +created_by: tb +creation_date: 2012-10-23T23:15:25Z + +[Term] +id: GO:1901529 +name: positive regulation of anion channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anion channel activity." [GOC:TermGenie] +synonym: "activation of anion channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of anion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of anion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of anion channel activity" EXACT [GOC:TermGenie] +is_a: GO:0010359 ! regulation of anion channel activity +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005253 ! anion channel activity +relationship: positively_regulates GO:0005253 ! anion channel activity +created_by: tb +creation_date: 2012-10-23T23:38:50Z + +[Term] +id: GO:1901530 +name: response to hypochlorite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus." [GOC:pr, GOC:TermGenie, PMID:22223481] +is_a: GO:0000302 ! response to reactive oxygen species +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +created_by: pr +creation_date: 2012-10-24T07:12:21Z + +[Term] +id: GO:1901531 +name: hypochlorite binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hypochlorite." [GOC:pr, GOC:TermGenie, PMID:22223481] +is_a: GO:0043168 ! anion binding +created_by: pr +creation_date: 2012-10-24T07:15:22Z + +[Term] +id: GO:1901532 +name: regulation of hematopoietic progenitor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] +synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT [] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002244 ! hematopoietic progenitor cell differentiation +relationship: regulates GO:0002244 ! hematopoietic progenitor cell differentiation +created_by: vk +creation_date: 2012-10-24T11:23:01Z + +[Term] +id: GO:1901533 +name: negative regulation of hematopoietic progenitor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] +synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "inhibition of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT [] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation +is_a: GO:1903707 ! negative regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation +relationship: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation +created_by: vk +creation_date: 2012-10-24T11:23:06Z + +[Term] +id: GO:1901534 +name: positive regulation of hematopoietic progenitor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] +synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "activation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "activation of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT [] +synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] +synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation +is_a: GO:1903708 ! positive regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation +relationship: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation +created_by: vk +creation_date: 2012-10-24T11:23:14Z + +[Term] +id: GO:1901535 +name: regulation of DNA demethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA demethylation." [GOC:TermGenie] +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080111 ! DNA demethylation +relationship: regulates GO:0080111 ! DNA demethylation +created_by: jl +creation_date: 2012-10-24T13:52:50Z + +[Term] +id: GO:1901536 +name: negative regulation of DNA demethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation." [GOC:TermGenie] +synonym: "down regulation of DNA demethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA demethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA demethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA demethylation" NARROW [GOC:TermGenie] +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:1901535 ! regulation of DNA demethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0080111 ! DNA demethylation +relationship: negatively_regulates GO:0080111 ! DNA demethylation +created_by: jl +creation_date: 2012-10-24T13:52:54Z + +[Term] +id: GO:1901537 +name: positive regulation of DNA demethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA demethylation." [GOC:TermGenie] +synonym: "activation of DNA demethylation" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA demethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA demethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA demethylation" EXACT [GOC:TermGenie] +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:1901535 ! regulation of DNA demethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0080111 ! DNA demethylation +relationship: positively_regulates GO:0080111 ! DNA demethylation +created_by: jl +creation_date: 2012-10-24T13:52:59Z + +[Term] +id: GO:1901538 +name: changes to DNA methylation involved in embryo development +namespace: biological_process +def: "The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression." [GOC:TermGenie] +synonym: "changes in DNA methylation involved in embryo development" EXACT [GOC:TermGenie] +synonym: "changes in DNA methylation involved in embryogenesis" EXACT [GOC:TermGenie] +synonym: "changes in DNA methylation involved in embryonal development" RELATED [GOC:TermGenie] +synonym: "DNA methylation or demethylation involved in embryogenesis" EXACT [GOC:TermGenie] +synonym: "DNA methylation or demethylation involved in embryonal development" EXACT [GOC:TermGenie] +is_a: GO:0044728 ! DNA methylation or demethylation +intersection_of: GO:0044728 ! DNA methylation or demethylation +intersection_of: part_of GO:0009790 ! embryo development +relationship: part_of GO:0009790 ! embryo development +created_by: jl +creation_date: 2012-10-25T14:53:43Z + +[Term] +id: GO:1901539 +name: ent-pimara-8(14),15-diene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ent-pimara-8(14),15-diene." [GOC:di, GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042214 ! terpene metabolic process +created_by: di +creation_date: 2012-10-25T15:38:13Z + +[Term] +id: GO:1901540 +name: ent-pimara-8(14),15-diene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene." [GOC:di, GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene breakdown" EXACT [GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene catabolism" EXACT [GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene degradation" EXACT [GOC:TermGenie] +is_a: GO:0046247 ! terpene catabolic process +is_a: GO:1901539 ! ent-pimara-8(14),15-diene metabolic process +created_by: di +creation_date: 2012-10-25T15:38:17Z + +[Term] +id: GO:1901541 +name: ent-pimara-8(14),15-diene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene." [GOC:di, GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046246 ! terpene biosynthetic process +is_a: GO:1901539 ! ent-pimara-8(14),15-diene metabolic process +created_by: di +creation_date: 2012-10-25T15:38:21Z + +[Term] +id: GO:1901542 +name: regulation of ent-pimara-8(14),15-diene biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +relationship: regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +created_by: di +creation_date: 2012-10-26T11:37:54Z + +[Term] +id: GO:1901543 +name: negative regulation of ent-pimara-8(14),15-diene biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "down regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ent-pimara-8(14),15-diene anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ent-pimara-8(14),15-diene biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of ent-pimara-8(14),15-diene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ent-pimara-8(14),15-diene formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ent-pimara-8(14),15-diene synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +is_a: GO:1901542 ! regulation of ent-pimara-8(14),15-diene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +relationship: negatively_regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +created_by: di +creation_date: 2012-10-26T11:37:58Z + +[Term] +id: GO:1901544 +name: positive regulation of ent-pimara-8(14),15-diene biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process." [GOC:di, GOC:TermGenie] +synonym: "activation of ent-pimara-8(14),15-diene anabolism" NARROW [GOC:TermGenie] +synonym: "activation of ent-pimara-8(14),15-diene biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of ent-pimara-8(14),15-diene biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ent-pimara-8(14),15-diene formation" NARROW [GOC:TermGenie] +synonym: "activation of ent-pimara-8(14),15-diene synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ent-pimara-8(14),15-diene anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ent-pimara-8(14),15-diene biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ent-pimara-8(14),15-diene biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ent-pimara-8(14),15-diene formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ent-pimara-8(14),15-diene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1901542 ! regulation of ent-pimara-8(14),15-diene biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +relationship: positively_regulates GO:1901541 ! ent-pimara-8(14),15-diene biosynthetic process +created_by: di +creation_date: 2012-10-26T11:38:07Z + +[Term] +id: GO:1901545 +name: response to raffinose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus." [GOC:TermGenie] +is_a: GO:0009743 ! response to carbohydrate +created_by: al +creation_date: 2012-10-26T14:32:23Z + +[Term] +id: GO:1901546 +name: regulation of synaptic vesicle lumen acidification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification." [GOC:TermGenie] +subset: goslim_synapse +synonym: "regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "regulation of synaptic vesicle lumen proton loading" EXACT syngo_official_label [] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0098693 ! regulation of synaptic vesicle cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097401 ! synaptic vesicle lumen acidification +relationship: regulates GO:0097401 ! synaptic vesicle lumen acidification +created_by: dsf +creation_date: 2012-10-26T16:09:24Z + +[Term] +id: GO:1901547 +name: negative regulation of synaptic vesicle lumen acidification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification." [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle lumen acidification" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle lumen pH reduction" NARROW [GOC:TermGenie] +synonym: "negative regulation of proton loading" EXACT syngo_official_label [] +synonym: "negative regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1901546 ! regulation of synaptic vesicle lumen acidification +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097401 ! synaptic vesicle lumen acidification +relationship: negatively_regulates GO:0097401 ! synaptic vesicle lumen acidification +created_by: dsf +creation_date: 2012-10-26T16:09:28Z + +[Term] +id: GO:1901548 +name: positive regulation of synaptic vesicle lumen acidification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification." [GOC:TermGenie] +synonym: "activation of synaptic vesicle lumen acidification" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle lumen pH reduction" NARROW [GOC:TermGenie] +synonym: "positive regulation of proton loading" EXACT syngo_official_label [] +synonym: "positive regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle lumen acidification" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle lumen pH reduction" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1901546 ! regulation of synaptic vesicle lumen acidification +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097401 ! synaptic vesicle lumen acidification +relationship: positively_regulates GO:0097401 ! synaptic vesicle lumen acidification +created_by: dsf +creation_date: 2012-10-26T16:09:32Z + +[Term] +id: GO:1901550 +name: regulation of endothelial cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] +is_a: GO:0045601 ! regulation of endothelial cell differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001885 ! endothelial cell development +relationship: regulates GO:0001885 ! endothelial cell development +created_by: pr +creation_date: 2012-10-30T12:59:50Z + +[Term] +id: GO:1901551 +name: negative regulation of endothelial cell development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] +synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie] +synonym: "inhibition of endothelial cell development" NARROW [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0045602 ! negative regulation of endothelial cell differentiation +is_a: GO:1901550 ! regulation of endothelial cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001885 ! endothelial cell development +relationship: negatively_regulates GO:0001885 ! endothelial cell development +created_by: pr +creation_date: 2012-10-30T12:59:54Z + +[Term] +id: GO:1901552 +name: positive regulation of endothelial cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] +synonym: "activation of endothelial cell development" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0045603 ! positive regulation of endothelial cell differentiation +is_a: GO:1901550 ! regulation of endothelial cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001885 ! endothelial cell development +relationship: positively_regulates GO:0001885 ! endothelial cell development +created_by: pr +creation_date: 2012-10-30T12:59:58Z + +[Term] +id: GO:1901553 +name: malonic acid transmembrane transport +namespace: biological_process +def: "The directed movement of malonic acid across a membrane." [GOC:al, GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "malonic acid membrane transport" EXACT [] +is_a: GO:1900752 ! malonic acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: pr +creation_date: 2012-10-30T15:23:54Z + +[Term] +id: GO:1901554 +name: response to paracetamol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus." [GOC:TermGenie] +synonym: "response to acetaminophen" EXACT [] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hp +creation_date: 2012-11-02T09:43:23Z + +[Term] +id: GO:1901555 +name: response to paclitaxel +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus." [GOC:TermGenie] +is_a: GO:0033993 ! response to lipid +is_a: GO:0097327 ! response to antineoplastic agent +created_by: hp +creation_date: 2012-11-02T09:46:08Z + +[Term] +id: GO:1901556 +name: response to candesartan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus." [GOC:TermGenie] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hp +creation_date: 2012-11-02T09:46:13Z + +[Term] +id: GO:1901557 +name: response to fenofibrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus." [GOC:TermGenie] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0045472 ! response to ether +is_a: GO:1901654 ! response to ketone +created_by: hp +creation_date: 2012-11-02T09:46:20Z + +[Term] +id: GO:1901558 +name: response to metformin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus." [GOC:TermGenie] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0042493 ! response to drug +created_by: hp +creation_date: 2012-11-02T09:46:24Z + +[Term] +id: GO:1901559 +name: response to ribavirin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0061479 ! response to reverse transcriptase inhibitor +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hp +creation_date: 2012-11-02T09:46:28Z + +[Term] +id: GO:1901560 +name: response to purvalanol A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus." [GOC:TermGenie] +is_a: GO:0014074 ! response to purine-containing compound +created_by: mah +creation_date: 2012-11-02T15:32:28Z + +[Term] +id: GO:1901561 +name: response to benomyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0060992 ! response to fungicide +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-02T15:32:33Z + +[Term] +id: GO:1901562 +name: response to paraquat +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus." [GOC:TermGenie] +is_a: GO:0009635 ! response to herbicide +is_a: GO:0010033 ! response to organic substance +created_by: mah +creation_date: 2012-11-02T15:32:41Z + +[Term] +id: GO:1901563 +name: response to camptothecin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus." [GOC:TermGenie] +synonym: "response to CPT" EXACT [GOC:mah] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043279 ! response to alkaloid +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +created_by: mah +creation_date: 2012-11-02T15:32:45Z + +[Term] +id: GO:1901564 +name: organonitrogen compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] +synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: pr +creation_date: 2012-11-04T15:17:52Z + +[Term] +id: GO:1901565 +name: organonitrogen compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie] +synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie] +synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie] +synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie] +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: pr +creation_date: 2012-11-04T15:17:56Z + +[Term] +id: GO:1901566 +name: organonitrogen compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie] +synonym: "organonitrogen compound anabolism" EXACT [GOC:TermGenie] +synonym: "organonitrogen compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "organonitrogen compound formation" EXACT [GOC:TermGenie] +synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: pr +creation_date: 2012-11-04T15:18:00Z + +[Term] +id: GO:1901567 +name: fatty acid derivative binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with fatty acid derivative." [GOC:pr, GOC:TermGenie] +is_a: GO:0005488 ! binding +created_by: pr +creation_date: 2012-11-04T17:13:28Z + +[Term] +id: GO:1901568 +name: fatty acid derivative metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fatty acid derivative." [GOC:pr, GOC:TermGenie] +synonym: "fatty acid derivative metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: pr +creation_date: 2012-11-04T17:13:36Z + +[Term] +id: GO:1901569 +name: fatty acid derivative catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fatty acid derivative." [GOC:pr, GOC:TermGenie] +synonym: "fatty acid derivative breakdown" EXACT [GOC:TermGenie] +synonym: "fatty acid derivative catabolism" EXACT [GOC:TermGenie] +synonym: "fatty acid derivative degradation" EXACT [GOC:TermGenie] +is_a: GO:1901568 ! fatty acid derivative metabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: pr +creation_date: 2012-11-04T17:13:40Z + +[Term] +id: GO:1901570 +name: fatty acid derivative biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fatty acid derivative." [GOC:pr, GOC:TermGenie] +synonym: "fatty acid derivative anabolism" EXACT [GOC:TermGenie] +synonym: "fatty acid derivative biosynthesis" EXACT [GOC:TermGenie] +synonym: "fatty acid derivative formation" EXACT [GOC:TermGenie] +synonym: "fatty acid derivative synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901568 ! fatty acid derivative metabolic process +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: pr +creation_date: 2012-11-04T17:13:44Z + +[Term] +id: GO:1901571 +name: fatty acid derivative transport +namespace: biological_process +def: "The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:pr, GOC:TermGenie] +is_a: GO:0071702 ! organic substance transport +created_by: pr +creation_date: 2012-11-04T17:13:49Z + +[Term] +id: GO:1901572 +name: obsolete chemical substance metabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways involving chemical substance." [GOC:pr, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "chemical substance metabolic process" EXACT [] +synonym: "chemical substance metabolism" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2012-11-04T18:10:32Z + +[Term] +id: GO:1901573 +name: obsolete chemical substance catabolic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of chemical substance." [GOC:pr, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "chemical substance breakdown" EXACT [GOC:TermGenie] +synonym: "chemical substance catabolic process" EXACT [] +synonym: "chemical substance catabolism" EXACT [GOC:TermGenie] +synonym: "chemical substance degradation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2012-11-04T18:10:36Z + +[Term] +id: GO:1901574 +name: obsolete chemical substance biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of chemical substance." [GOC:pr, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "chemical substance anabolism" EXACT [GOC:TermGenie] +synonym: "chemical substance biosynthesis" EXACT [GOC:TermGenie] +synonym: "chemical substance biosynthetic process" EXACT [] +synonym: "chemical substance formation" EXACT [GOC:TermGenie] +synonym: "chemical substance synthesis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2012-11-04T18:10:40Z + +[Term] +id: GO:1901575 +name: organic substance catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] +synonym: "organic molecular entity breakdown" EXACT [GOC:TermGenie] +synonym: "organic molecular entity catabolic process" EXACT [] +synonym: "organic molecular entity catabolism" EXACT [GOC:TermGenie] +synonym: "organic molecular entity degradation" EXACT [GOC:TermGenie] +synonym: "organic substance breakdown" EXACT [] +synonym: "organic substance catabolism" EXACT [] +synonym: "organic substance degradation" EXACT [] +is_a: GO:0009056 ! catabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: pr +creation_date: 2012-11-05T11:04:36Z + +[Term] +id: GO:1901576 +name: organic substance biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] +synonym: "organic molecular entity anabolism" EXACT [GOC:TermGenie] +synonym: "organic molecular entity biosynthesis" EXACT [GOC:TermGenie] +synonym: "organic molecular entity biosynthetic process" EXACT [] +synonym: "organic molecular entity formation" EXACT [GOC:TermGenie] +synonym: "organic molecular entity synthesis" EXACT [GOC:TermGenie] +synonym: "organic substance anabolism" EXACT [] +synonym: "organic substance biosynthesis" EXACT [] +synonym: "organic substance formation" EXACT [] +synonym: "organic substance synthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: pr +creation_date: 2012-11-05T11:04:40Z + +[Term] +id: GO:1901577 +name: regulation of alkane biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] +synonym: "regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "regulation of alkane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043447 ! alkane biosynthetic process +relationship: regulates GO:0043447 ! alkane biosynthetic process +created_by: dhl +creation_date: 2012-11-05T21:54:06Z + +[Term] +id: GO:1901578 +name: negative regulation of alkane biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "down regulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "downregulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of alkane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of alkane formation" EXACT [GOC:TermGenie] +synonym: "inhibition of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of alkane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043447 ! alkane biosynthetic process +relationship: negatively_regulates GO:0043447 ! alkane biosynthetic process +created_by: dhl +creation_date: 2012-11-05T21:54:11Z + +[Term] +id: GO:1901579 +name: positive regulation of alkane biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process." [GOC:TermGenie] +synonym: "activation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "activation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of alkane biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of alkane formation" EXACT [GOC:TermGenie] +synonym: "activation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "up regulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of alkane synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of alkane anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of alkane biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of alkane biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of alkane formation" EXACT [GOC:TermGenie] +synonym: "upregulation of alkane synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1901577 ! regulation of alkane biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043447 ! alkane biosynthetic process +relationship: positively_regulates GO:0043447 ! alkane biosynthetic process +created_by: dhl +creation_date: 2012-11-05T21:54:19Z + +[Term] +id: GO:1901580 +name: regulation of telomeric RNA transcription from RNA pol II promoter +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter." [GOC:TermGenie] +synonym: "regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +relationship: regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +created_by: al +creation_date: 2012-11-06T11:07:16Z + +[Term] +id: GO:1901581 +name: negative regulation of telomeric RNA transcription from RNA pol II promoter +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter." [GOC:TermGenie] +synonym: "down regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of telomeric RNA transcription from RNA pol II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1901580 ! regulation of telomeric RNA transcription from RNA pol II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +relationship: negatively_regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +created_by: al +creation_date: 2012-11-06T11:07:21Z + +[Term] +id: GO:1901582 +name: positive regulation of telomeric RNA transcription from RNA pol II promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter." [GOC:TermGenie] +synonym: "activation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "activation of telomeric RNA transcription from RNA pol II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric RNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric RNA transcription from RNA pol II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1901580 ! regulation of telomeric RNA transcription from RNA pol II promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +relationship: positively_regulates GO:0097394 ! telomeric repeat-containing RNA transcription by RNA polymerase II +created_by: al +creation_date: 2012-11-06T11:07:25Z + +[Term] +id: GO:1901583 +name: tetrapeptide transmembrane transport +namespace: biological_process +def: "The directed movement of tetrapeptide across a membrane." [GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "tetrapeptide membrane transport" EXACT [] +is_a: GO:0035672 ! oligopeptide transmembrane transport +created_by: jl +creation_date: 2012-11-06T15:40:02Z + +[Term] +id: GO:1901584 +name: tetrapeptide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of tetrapeptide from one side of a membrane to the other." [GOC:TermGenie] +is_a: GO:0035673 ! oligopeptide transmembrane transporter activity +relationship: part_of GO:1901583 ! tetrapeptide transmembrane transport +created_by: jl +creation_date: 2012-11-06T15:40:10Z + +[Term] +id: GO:1901585 +name: regulation of acid-sensing ion channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity." [GOC:TermGenie] +synonym: "regulation of ASIC activity" EXACT [GOC:TermGenie] +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044736 ! acid-sensing ion channel activity +relationship: regulates GO:0044736 ! acid-sensing ion channel activity +created_by: jl +creation_date: 2012-11-07T13:37:24Z + +[Term] +id: GO:1901586 +name: negative regulation of acid-sensing ion channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity." [GOC:TermGenie] +synonym: "down regulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "inhibition of acid-sensing ion channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ASIC activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ASIC activity" EXACT [GOC:TermGenie] +is_a: GO:1901585 ! regulation of acid-sensing ion channel activity +is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044736 ! acid-sensing ion channel activity +relationship: negatively_regulates GO:0044736 ! acid-sensing ion channel activity +created_by: jl +creation_date: 2012-11-07T13:37:32Z + +[Term] +id: GO:1901587 +name: positive regulation of acid-sensing ion channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity." [GOC:TermGenie] +synonym: "activation of acid-sensing ion channel activity" NARROW [GOC:TermGenie] +synonym: "activation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ASIC activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acid-sensing ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ASIC activity" EXACT [GOC:TermGenie] +is_a: GO:1901585 ! regulation of acid-sensing ion channel activity +is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044736 ! acid-sensing ion channel activity +relationship: positively_regulates GO:0044736 ! acid-sensing ion channel activity +created_by: jl +creation_date: 2012-11-07T13:37:37Z + +[Term] +id: GO:1901588 +name: dendritic microtubule +namespace: cellular_component +def: "Any microtubule in a dendrite, a neuron projection." [GOC:TermGenie, NIF_Subcellular:sao110773650] +synonym: "microtubule of dendrite" EXACT [GOC:TermGenie] +synonym: "microtubulus of dendrite" EXACT [GOC:TermGenie] +xref: NIF_Subcellular:sao110773650 +is_a: GO:0005874 ! microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:0030425 ! dendrite +relationship: part_of GO:0030425 ! dendrite +created_by: pr +creation_date: 2012-11-07T14:37:30Z + +[Term] +id: GO:1901589 +name: axon microtubule bundle +namespace: cellular_component +def: "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment." [GOC:TermGenie, NIF_Subcellular:sao707332678] +synonym: "axon microtubule fascicle" EXACT [] +synonym: "microtubule bundle of axon" EXACT [GOC:TermGenie] +synonym: "microtubule fascicle of axon" EXACT [GOC:TermGenie] +xref: NIF_Subcellular:sao707332678 +is_a: GO:0097427 ! microtubule bundle +intersection_of: GO:0097427 ! microtubule bundle +intersection_of: part_of GO:0030424 ! axon +relationship: part_of GO:0030424 ! axon +created_by: pr +creation_date: 2012-11-07T15:37:12Z + +[Term] +id: GO:1901591 +name: regulation of double-strand break repair via break-induced replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication." [GOC:TermGenie] +is_a: GO:0010569 ! regulation of double-strand break repair via homologous recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000727 ! double-strand break repair via break-induced replication +relationship: regulates GO:0000727 ! double-strand break repair via break-induced replication +created_by: al +creation_date: 2012-11-07T16:37:34Z + +[Term] +id: GO:1901592 +name: negative regulation of double-strand break repair via break-induced replication +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication." [GOC:TermGenie] +synonym: "down regulation of double-strand break repair via break-induced replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of double-strand break repair via break-induced replication" EXACT [GOC:TermGenie] +synonym: "downregulation of double-strand break repair via break-induced replication" EXACT [GOC:TermGenie] +synonym: "inhibition of double-strand break repair via break-induced replication" NARROW [GOC:TermGenie] +is_a: GO:1901591 ! regulation of double-strand break repair via break-induced replication +is_a: GO:2000042 ! negative regulation of double-strand break repair via homologous recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000727 ! double-strand break repair via break-induced replication +relationship: negatively_regulates GO:0000727 ! double-strand break repair via break-induced replication +created_by: al +creation_date: 2012-11-07T16:37:39Z + +[Term] +id: GO:1901593 +name: response to GW 7647 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus." [GOC:TermGenie] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T17:16:48Z + +[Term] +id: GO:1901594 +name: response to capsazepine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T17:16:53Z + +[Term] +id: GO:1901595 +name: response to hesperadin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus." [GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0014075 ! response to amine +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T17:16:57Z + +[Term] +id: GO:1901596 +name: response to reversine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus." [GOC:TermGenie] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T17:17:01Z + +[Term] +id: GO:1901597 +name: response to carbendazim +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus." [GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0060992 ! response to fungicide +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2012-11-07T17:17:06Z + +[Term] +id: GO:1901598 +name: (-)-pinoresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-pinoresinol." [GOC:TermGenie] +synonym: "(-)-pinoresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: tb +creation_date: 2012-11-08T01:15:57Z + +[Term] +id: GO:1901599 +name: (-)-pinoresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-pinoresinol." [GOC:TermGenie] +synonym: "(-)-pinoresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-pinoresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-pinoresinol formation" EXACT [GOC:TermGenie] +synonym: "(-)-pinoresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901598 ! (-)-pinoresinol metabolic process +created_by: tb +creation_date: 2012-11-08T01:16:05Z + +[Term] +id: GO:1901600 +name: strigolactone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving strigolactone." [GOC:TermGenie] +synonym: "strigolactone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:1901334 ! lactone metabolic process +created_by: tb +creation_date: 2012-11-08T01:20:09Z + +[Term] +id: GO:1901601 +name: strigolactone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of strigolactone." [GOC:TermGenie] +synonym: "strigolactone anabolism" EXACT [GOC:TermGenie] +synonym: "strigolactone biosynthesis" EXACT [GOC:TermGenie] +synonym: "strigolactone formation" EXACT [GOC:TermGenie] +synonym: "strigolactone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:1901336 ! lactone biosynthetic process +is_a: GO:1901600 ! strigolactone metabolic process +created_by: tb +creation_date: 2012-11-08T01:20:13Z + +[Term] +id: GO:1901602 +name: dethiobiotin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dethiobiotin." [GOC:TermGenie] +is_a: GO:0033218 ! amide binding +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: al +creation_date: 2012-11-08T14:09:14Z + +[Term] +id: GO:1901604 +name: dethiobiotin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of dethiobiotin from one side of a membrane to the other." [GOC:TermGenie] +is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity +is_a: GO:0042887 ! amide transmembrane transporter activity +created_by: al +creation_date: 2012-11-08T14:42:53Z + +[Term] +id: GO:1901605 +name: alpha-amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] +synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006520 ! cellular amino acid metabolic process +created_by: tb +creation_date: 2012-11-08T17:39:50Z + +[Term] +id: GO:1901606 +name: alpha-amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie] +synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] +synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] +synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0009063 ! cellular amino acid catabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: tb +creation_date: 2012-11-08T17:39:54Z + +[Term] +id: GO:1901607 +name: alpha-amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie] +synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] +synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] +synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008652 ! cellular amino acid biosynthetic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: tb +creation_date: 2012-11-08T17:39:58Z + +[Term] +id: GO:1901608 +name: regulation of vesicle transport along microtubule +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] +synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +is_a: GO:1902513 ! regulation of organelle transport along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0047496 ! vesicle transport along microtubule +relationship: regulates GO:0047496 ! vesicle transport along microtubule +created_by: hjd +creation_date: 2012-11-08T21:49:44Z + +[Term] +id: GO:1901609 +name: negative regulation of vesicle transport along microtubule +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] +synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "inhibition of vesicle transport along microtubule" NARROW [GOC:TermGenie] +synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:1901608 ! regulation of vesicle transport along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0047496 ! vesicle transport along microtubule +relationship: negatively_regulates GO:0047496 ! vesicle transport along microtubule +created_by: hjd +creation_date: 2012-11-08T21:49:48Z + +[Term] +id: GO:1901610 +name: positive regulation of vesicle transport along microtubule +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] +synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "activation of vesicle transport along microtubule" NARROW [GOC:TermGenie] +synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] +synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:1901608 ! regulation of vesicle transport along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0047496 ! vesicle transport along microtubule +relationship: positively_regulates GO:0047496 ! vesicle transport along microtubule +created_by: hjd +creation_date: 2012-11-08T21:49:53Z + +[Term] +id: GO:1901611 +name: phosphatidylglycerol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylglycerol." [GOC:kmv, GOC:TermGenie] +is_a: GO:0005543 ! phospholipid binding +created_by: kmv +creation_date: 2012-11-12T21:18:24Z + +[Term] +id: GO:1901612 +name: cardiolipin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cardiolipin." [GOC:kmv, GOC:TermGenie] +is_a: GO:1901611 ! phosphatidylglycerol binding +created_by: kmv +creation_date: 2012-11-12T21:19:50Z + +[Term] +id: GO:1901613 +name: negative regulation of terminal button organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization." [GOC:TermGenie, PMID:22426000] +synonym: "down regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "down regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal button organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal button organization" EXACT [GOC:TermGenie] +synonym: "downregulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal button organization" EXACT [GOC:TermGenie] +synonym: "inhibition of bouton organization" NARROW [GOC:TermGenie] +synonym: "inhibition of presynaptic bouton organization" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic bouton organization" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal bouton organization" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal button organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal button organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of terminal button organisation" EXACT [GOC:TermGenie] +is_a: GO:1905809 ! negative regulation of synapse organization +is_a: GO:2000331 ! regulation of terminal button organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072553 ! terminal button organization +relationship: negatively_regulates GO:0072553 ! terminal button organization +created_by: lb +creation_date: 2012-11-13T10:40:51Z + +[Term] +id: GO:1901614 +name: positive regulation of terminal button organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of terminal button organization." [GOC:TermGenie, PMID:22426000] +synonym: "activation of bouton organization" NARROW [GOC:TermGenie] +synonym: "activation of presynaptic bouton organization" NARROW [GOC:TermGenie] +synonym: "activation of synaptic bouton organization" NARROW [GOC:TermGenie] +synonym: "activation of terminal bouton organization" NARROW [GOC:TermGenie] +synonym: "activation of terminal button organisation" NARROW [GOC:TermGenie] +synonym: "activation of terminal button organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal button organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal button organization" EXACT [GOC:TermGenie] +synonym: "upregulation of bouton organization" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic bouton organization" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal bouton organization" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal button organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal button organization" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:2000331 ! regulation of terminal button organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072553 ! terminal button organization +relationship: positively_regulates GO:0072553 ! terminal button organization +created_by: lb +creation_date: 2012-11-13T10:40:58Z + +[Term] +id: GO:1901615 +name: organic hydroxy compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving organic hydroxy compound." [GOC:pr, GOC:TermGenie] +synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: pr +creation_date: 2012-11-13T12:54:27Z + +[Term] +id: GO:1901616 +name: organic hydroxy compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." [GOC:pr, GOC:TermGenie] +synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie] +synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie] +synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie] +is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: pr +creation_date: 2012-11-13T12:54:31Z + +[Term] +id: GO:1901617 +name: organic hydroxy compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." [GOC:pr, GOC:TermGenie] +synonym: "organic hydroxy compound anabolism" EXACT [GOC:TermGenie] +synonym: "organic hydroxy compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "organic hydroxy compound formation" EXACT [GOC:TermGenie] +synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901576 ! organic substance biosynthetic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: pr +creation_date: 2012-11-13T12:54:36Z + +[Term] +id: GO:1901618 +name: organic hydroxy compound transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +created_by: pr +creation_date: 2012-11-13T12:59:01Z + +[Term] +id: GO:1901619 +name: obsolete tRNA methylation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen." [GOC:TermGenie, PMID:23074192] +is_obsolete: true +created_by: al +creation_date: 2012-11-13T14:36:00Z + +[Term] +id: GO:1901620 +name: regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning." [GOC:TermGenie] +synonym: "regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +is_a: GO:0008589 ! regulation of smoothened signaling pathway +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +relationship: regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +created_by: krc +creation_date: 2012-11-13T20:11:57Z + +[Term] +id: GO:1901621 +name: negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning." [GOC:TermGenie] +synonym: "down regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "down-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "downregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "downregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "downregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "downregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "inhibition of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "inhibition of hh signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "inhibition of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "inhibition of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "negative regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "negative regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "negative regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +is_a: GO:0045879 ! negative regulation of smoothened signaling pathway +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +relationship: negatively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +created_by: krc +creation_date: 2012-11-13T20:12:01Z + +[Term] +id: GO:1901622 +name: positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning." [GOC:TermGenie] +synonym: "activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "activation of hh signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "activation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" NARROW [GOC:TermGenie] +synonym: "positive regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "positive regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "positive regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "up-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "upregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +synonym: "upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0045880 ! positive regulation of smoothened signaling pathway +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +relationship: positively_regulates GO:0060831 ! smoothened signaling pathway involved in dorsal/ventral neural tube patterning +created_by: krc +creation_date: 2012-11-13T20:12:06Z + +[Term] +id: GO:1901623 +name: regulation of lymphocyte chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis." [GOC:TermGenie] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +is_a: GO:2000401 ! regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048247 ! lymphocyte chemotaxis +relationship: regulates GO:0048247 ! lymphocyte chemotaxis +created_by: tb +creation_date: 2012-11-13T23:03:23Z + +[Term] +id: GO:1901624 +name: negative regulation of lymphocyte chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis." [GOC:TermGenie] +synonym: "down regulation of lymphocyte chemotaxis" EXACT [GOC:TermGenie] +synonym: "down-regulation of lymphocyte chemotaxis" EXACT [GOC:TermGenie] +synonym: "downregulation of lymphocyte chemotaxis" EXACT [GOC:TermGenie] +synonym: "inhibition of lymphocyte chemotaxis" NARROW [GOC:TermGenie] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:1901623 ! regulation of lymphocyte chemotaxis +is_a: GO:2000402 ! negative regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048247 ! lymphocyte chemotaxis +relationship: negatively_regulates GO:0048247 ! lymphocyte chemotaxis +created_by: tb +creation_date: 2012-11-13T23:03:28Z + +[Term] +id: GO:1901625 +name: cellular response to ergosterol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus." [GOC:TermGenie] +is_a: GO:0036315 ! cellular response to sterol +is_a: GO:0097306 ! cellular response to alcohol +created_by: dph +creation_date: 2012-11-14T13:53:51Z + +[Term] +id: GO:1901626 +name: regulation of postsynaptic membrane organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "regulation of post-synaptic membrane organization" EXACT [] +synonym: "regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +is_a: GO:0099175 ! regulation of postsynapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001941 ! postsynaptic membrane organization +relationship: regulates GO:0001941 ! postsynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:15Z + +[Term] +id: GO:1901627 +name: negative regulation of postsynaptic membrane organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "down regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "downregulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "inhibition of postsynaptic membrane organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of postsynaptic membrane organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of post-synaptic membrane organization" EXACT [] +synonym: "negative regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +is_a: GO:1901626 ! regulation of postsynaptic membrane organization +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001941 ! postsynaptic membrane organization +relationship: negatively_regulates GO:0001941 ! postsynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:20Z + +[Term] +id: GO:1901628 +name: positive regulation of postsynaptic membrane organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "activation of postsynaptic membrane organisation" NARROW [GOC:TermGenie] +synonym: "activation of postsynaptic membrane organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of post-synaptic membrane organization" EXACT [] +synonym: "positive regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "upregulation of postsynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of postsynaptic membrane organization" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901626 ! regulation of postsynaptic membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001941 ! postsynaptic membrane organization +relationship: positively_regulates GO:0001941 ! postsynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:24Z + +[Term] +id: GO:1901629 +name: regulation of presynaptic membrane organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of presynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "regulation of pre-synaptic membrane organization" EXACT [] +synonym: "regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097090 ! presynaptic membrane organization +relationship: regulates GO:0097090 ! presynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:32Z + +[Term] +id: GO:1901630 +name: negative regulation of presynaptic membrane organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "down regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "inhibition of presynaptic membrane organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of presynaptic membrane organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of pre-synaptic membrane organization" EXACT [] +synonym: "negative regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +is_a: GO:1901629 ! regulation of presynaptic membrane organization +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097090 ! presynaptic membrane organization +relationship: negatively_regulates GO:0097090 ! presynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:36Z + +[Term] +id: GO:1901631 +name: positive regulation of presynaptic membrane organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "activation of presynaptic membrane organisation" NARROW [GOC:TermGenie] +synonym: "activation of presynaptic membrane organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of pre-synaptic membrane organization" EXACT [] +synonym: "positive regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic membrane organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic membrane organization" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901629 ! regulation of presynaptic membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097090 ! presynaptic membrane organization +relationship: positively_regulates GO:0097090 ! presynaptic membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:40Z + +[Term] +id: GO:1901632 +name: regulation of synaptic vesicle membrane organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048499 ! synaptic vesicle membrane organization +relationship: regulates GO:0048499 ! synaptic vesicle membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:48Z + +[Term] +id: GO:1901633 +name: negative regulation of synaptic vesicle membrane organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "down regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle membrane organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle membrane organization" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle membrane organization and biogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1901632 ! regulation of synaptic vesicle membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048499 ! synaptic vesicle membrane organization +relationship: negatively_regulates GO:0048499 ! synaptic vesicle membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:55Z + +[Term] +id: GO:1901634 +name: positive regulation of synaptic vesicle membrane organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization." [GOC:TermGenie, PMID:22426000] +synonym: "activation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle membrane organisation" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle membrane organization" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of SLMV biogenesis" NARROW [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle membrane organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle membrane organization" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle membrane organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901632 ! regulation of synaptic vesicle membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048499 ! synaptic vesicle membrane organization +relationship: positively_regulates GO:0048499 ! synaptic vesicle membrane organization +created_by: ans +creation_date: 2012-11-15T11:40:59Z + +[Term] +id: GO:1901635 +name: obsolete regulation of maintenance of presynaptic active zone structure +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of presynaptic active zone structure." [GOC:TermGenie, PMID:22426000] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of maintenance of presynaptic active zone structure" EXACT [] +is_obsolete: true +created_by: ans +creation_date: 2012-11-15T14:17:03Z + +[Term] +id: GO:1901636 +name: obsolete negative regulation of maintenance of presynaptic active zone structure +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of presynaptic active zone structure." [GOC:TermGenie, PMID:22426000] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +synonym: "inhibition of maintenance of presynaptic active zone structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of maintenance of presynaptic active zone structure" EXACT [] +is_obsolete: true +created_by: ans +creation_date: 2012-11-15T14:17:07Z + +[Term] +id: GO:1901637 +name: obsolete positive regulation of maintenance of presynaptic active zone structure +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of presynaptic active zone structure." [GOC:TermGenie, PMID:22426000] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of maintenance of presynaptic active zone structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of maintenance of presynaptic active zone structure" EXACT [] +synonym: "up regulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of presynaptic active zone structure" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: ans +creation_date: 2012-11-15T14:17:16Z + +[Term] +id: GO:1901638 +name: obsolete copper ion import into ascospore-type prospore +namespace: biological_process +def: "OBSOLETE. Any copper ion import that takes place in ascospore-type prospore." [GOC:TermGenie] +comment: https://sourceforge.net/tracker/index.php?func=detail&aid=3510080&group_id=36855&atid=440764 +synonym: "copper ion import into ascospore-type prospore" EXACT [] +synonym: "copper ion uptake in ascospore-type prospore" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-11-15T15:44:04Z + +[Term] +id: GO:1901639 +name: XDP catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of XDP." [GOC:TermGenie] +synonym: "XDP breakdown" EXACT [GOC:TermGenie] +synonym: "XDP catabolism" EXACT [GOC:TermGenie] +synonym: "XDP degradation" EXACT [GOC:TermGenie] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0009181 ! purine ribonucleoside diphosphate catabolic process +created_by: tb +creation_date: 2012-11-15T22:56:26Z + +[Term] +id: GO:1901640 +name: XTP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with XTP." [GOC:TermGenie] +is_a: GO:0032555 ! purine ribonucleotide binding +is_a: GO:0035639 ! purine ribonucleoside triphosphate binding +created_by: tb +creation_date: 2012-11-15T22:56:35Z + +[Term] +id: GO:1901641 +name: ITP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ITP." [GOC:TermGenie] +is_a: GO:0032555 ! purine ribonucleotide binding +is_a: GO:0035639 ! purine ribonucleoside triphosphate binding +created_by: tb +creation_date: 2012-11-15T22:56:39Z + +[Term] +id: GO:1901642 +name: nucleoside transmembrane transport +namespace: biological_process +def: "The directed movement of nucleoside across a membrane." [GOC:pr, GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "nucleoside membrane transport" EXACT [] +is_a: GO:0015858 ! nucleoside transport +is_a: GO:0055085 ! transmembrane transport +created_by: pr +creation_date: 2012-11-16T13:32:01Z + +[Term] +id: GO:1901643 +name: obsolete regulation of tRNA methylation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation." [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-11-16T14:44:08Z + +[Term] +id: GO:1901644 +name: obsolete positive regulation of tRNA methylation in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation." [GOC:TermGenie] +synonym: "activation of tRNA methylation in response to nitrogen starvation" NARROW [GOC:TermGenie] +synonym: "up regulation of tRNA methylation in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA methylation in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA methylation in response to nitrogen starvation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2012-11-16T14:44:12Z + +[Term] +id: GO:1901645 +name: regulation of synoviocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synoviocyte proliferation." [GOC:TermGenie] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002941 ! synoviocyte proliferation +relationship: regulates GO:0002941 ! synoviocyte proliferation +created_by: hjd +creation_date: 2012-11-16T20:16:23Z + +[Term] +id: GO:1901646 +name: negative regulation of synoviocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation." [GOC:TermGenie] +synonym: "down regulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of synoviocyte proliferation" NARROW [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:1901645 ! regulation of synoviocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002941 ! synoviocyte proliferation +relationship: negatively_regulates GO:0002941 ! synoviocyte proliferation +created_by: hjd +creation_date: 2012-11-16T20:16:27Z + +[Term] +id: GO:1901647 +name: positive regulation of synoviocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation." [GOC:TermGenie] +synonym: "activation of synoviocyte proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of synoviocyte proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:1901645 ! regulation of synoviocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002941 ! synoviocyte proliferation +relationship: positively_regulates GO:0002941 ! synoviocyte proliferation +created_by: hjd +creation_date: 2012-11-16T20:16:32Z + +[Term] +id: GO:1901648 +name: regulation of actomyosin contractile ring localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization." [GOC:TermGenie] +synonym: "regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0032879 ! regulation of localization +is_a: GO:0032954 ! regulation of cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032187 ! actomyosin contractile ring localization +relationship: regulates GO:0032187 ! actomyosin contractile ring localization +created_by: vw +creation_date: 2012-11-19T13:42:45Z + +[Term] +id: GO:1901649 +name: negative regulation of actomyosin contractile ring localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization." [GOC:TermGenie] +synonym: "down regulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "down regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "down regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "downregulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "inhibition of actomyosin contractile ring localization" NARROW [GOC:TermGenie] +synonym: "inhibition of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "inhibition of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:1901648 ! regulation of actomyosin contractile ring localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032187 ! actomyosin contractile ring localization +relationship: negatively_regulates GO:0032187 ! actomyosin contractile ring localization +created_by: vw +creation_date: 2012-11-19T13:42:49Z + +[Term] +id: GO:1901650 +name: positive regulation of actomyosin contractile ring localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization." [GOC:TermGenie] +synonym: "activation of actomyosin contractile ring localization" NARROW [GOC:TermGenie] +synonym: "activation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "activation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "up regulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "up regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "up regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "upregulation of contractile ring localisation involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of contractile ring localization involved in cell cycle cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:1901648 ! regulation of actomyosin contractile ring localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032187 ! actomyosin contractile ring localization +relationship: positively_regulates GO:0032187 ! actomyosin contractile ring localization +created_by: vw +creation_date: 2012-11-19T13:42:54Z + +[Term] +id: GO:1901651 +name: regulation of mitotic chromosome decondensation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation." [GOC:TermGenie] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007083 ! mitotic chromosome decondensation +relationship: regulates GO:0007083 ! mitotic chromosome decondensation +created_by: dph +creation_date: 2012-11-19T14:13:58Z + +[Term] +id: GO:1901652 +name: response to peptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-11-20T09:45:15Z + +[Term] +id: GO:1901653 +name: cellular response to peptide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901652 ! response to peptide +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: pr +creation_date: 2012-11-20T09:45:19Z + +[Term] +id: GO:1901654 +name: response to ketone +namespace: biological_process +alt_id: GO:1990369 +def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] +synonym: "process resulting in tolerance to ketone" NARROW [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-11-20T10:55:47Z + +[Term] +id: GO:1901655 +name: cellular response to ketone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus." [GOC:pr, GOC:TermGenie] +is_a: GO:1901654 ! response to ketone +is_a: GO:1901701 ! cellular response to oxygen-containing compound +created_by: pr +creation_date: 2012-11-20T10:55:51Z + +[Term] +id: GO:1901656 +name: glycoside transport +namespace: biological_process +def: "The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:pr, GOC:TermGenie] +is_a: GO:1901264 ! carbohydrate derivative transport +created_by: pr +creation_date: 2012-11-20T11:59:16Z + +[Term] +id: GO:1901657 +name: glycosyl compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycosyl compound." [GOC:pr, GOC:TermGenie] +synonym: "glycosyl compound metabolism" EXACT [GOC:TermGenie] +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: pr +creation_date: 2012-11-20T14:24:07Z + +[Term] +id: GO:1901658 +name: glycosyl compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycosyl compound." [GOC:pr, GOC:TermGenie] +synonym: "glycosyl compound breakdown" EXACT [GOC:TermGenie] +synonym: "glycosyl compound catabolism" EXACT [GOC:TermGenie] +synonym: "glycosyl compound degradation" EXACT [GOC:TermGenie] +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:1901657 ! glycosyl compound metabolic process +created_by: pr +creation_date: 2012-11-20T14:24:11Z + +[Term] +id: GO:1901659 +name: glycosyl compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycosyl compound." [GOC:pr, GOC:TermGenie] +synonym: "glycosyl compound anabolism" EXACT [GOC:TermGenie] +synonym: "glycosyl compound biosynthesis" EXACT [GOC:TermGenie] +synonym: "glycosyl compound formation" EXACT [GOC:TermGenie] +synonym: "glycosyl compound synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:1901657 ! glycosyl compound metabolic process +created_by: pr +creation_date: 2012-11-20T14:24:19Z + +[Term] +id: GO:1901660 +name: calcium ion export +namespace: biological_process +def: "The directed movement of calcium ion out of a cell or organelle." [GOC:TermGenie] +is_a: GO:0006816 ! calcium ion transport +created_by: jl +creation_date: 2012-11-20T14:33:07Z + +[Term] +id: GO:1901661 +name: quinone metabolic process +namespace: biological_process +alt_id: GO:0042375 +def: "The chemical reactions and pathways involving quinone." [GOC:go_curators, GOC:pr, GOC:TermGenie] +synonym: "quinone cofactor metabolic process" RELATED [] +synonym: "quinone cofactor metabolism" RELATED [] +synonym: "quinone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0051186 ! cofactor metabolic process +created_by: pr +creation_date: 2012-11-20T14:44:39Z + +[Term] +id: GO:1901662 +name: quinone catabolic process +namespace: biological_process +alt_id: GO:0042378 +def: "The chemical reactions and pathways resulting in the breakdown of quinone." [GOC:go_curators, GOC:pr, GOC:TermGenie] +synonym: "quinone breakdown" EXACT [GOC:TermGenie] +synonym: "quinone catabolism" EXACT [GOC:TermGenie] +synonym: "quinone cofactor breakdown" RELATED [] +synonym: "quinone cofactor catabolic process" RELATED [] +synonym: "quinone cofactor catabolism" RELATED [] +synonym: "quinone cofactor degradation" RELATED [] +synonym: "quinone degradation" EXACT [GOC:TermGenie] +is_a: GO:0009109 ! coenzyme catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: pr +creation_date: 2012-11-20T14:44:44Z + +[Term] +id: GO:1901663 +name: quinone biosynthetic process +namespace: biological_process +alt_id: GO:0045426 +def: "The chemical reactions and pathways resulting in the formation of quinone." [GOC:mb, GOC:pr, GOC:TermGenie] +synonym: "quinone anabolism" EXACT [GOC:TermGenie] +synonym: "quinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "quinone cofactor anabolism" RELATED [] +synonym: "quinone cofactor biosynthesis" RELATED [] +synonym: "quinone cofactor biosynthetic process" RELATED [] +synonym: "quinone cofactor formation" RELATED [] +synonym: "quinone cofactor synthesis" RELATED [] +synonym: "quinone formation" EXACT [GOC:TermGenie] +synonym: "quinone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1901661 ! quinone metabolic process +created_by: pr +creation_date: 2012-11-20T14:44:48Z + +[Term] +id: GO:1901664 +name: regulation of NAD+ ADP-ribosyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +relationship: regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +created_by: vk +creation_date: 2012-11-20T18:50:07Z + +[Term] +id: GO:1901665 +name: negative regulation of NAD+ ADP-ribosyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "inhibition of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of NAD+ ADP-ribosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1901664 ! regulation of NAD+ ADP-ribosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +relationship: negatively_regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +created_by: vk +creation_date: 2012-11-20T18:50:15Z + +[Term] +id: GO:1901666 +name: positive regulation of NAD+ ADP-ribosyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity." [GOC:BHF, GOC:TermGenie] +synonym: "activation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "activation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "activation of NAD+ ADP-ribosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "activation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "activation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "activation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "activation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1901664 ! regulation of NAD+ ADP-ribosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +relationship: positively_regulates GO:0003950 ! NAD+ ADP-ribosyltransferase activity +created_by: vk +creation_date: 2012-11-20T18:50:20Z + +[Term] +id: GO:1901667 +name: negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration." [GOC:dph, GOC:TermGenie, PMID:21272575] +synonym: "down regulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of satellite cell activation involved in skeletal muscle regeneration" EXACT [GOC:TermGenie] +synonym: "inhibition of satellite cell activation involved in skeletal muscle regeneration" NARROW [GOC:TermGenie] +is_a: GO:0014717 ! regulation of satellite cell activation involved in skeletal muscle regeneration +is_a: GO:0043417 ! negative regulation of skeletal muscle tissue regeneration +is_a: GO:0050866 ! negative regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration +relationship: negatively_regulates GO:0014901 ! satellite cell activation involved in skeletal muscle regeneration +created_by: dph +creation_date: 2012-11-21T16:21:11Z + +[Term] +id: GO:1901668 +name: regulation of superoxide dismutase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] +synonym: "regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "regulation of SOD" RELATED [GOC:TermGenie] +synonym: "regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "regulation of SODF" RELATED [GOC:TermGenie] +synonym: "regulation of SODS" RELATED [GOC:TermGenie] +synonym: "regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +is_a: GO:2000121 ! regulation of removal of superoxide radicals +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004784 ! superoxide dismutase activity +relationship: regulates GO:0004784 ! superoxide dismutase activity +created_by: tb +creation_date: 2012-11-21T20:46:42Z + +[Term] +id: GO:1901670 +name: negative regulation of superoxide dismutase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] +synonym: "down regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "down regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "down regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "down regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "down regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "down regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "down regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "down regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "down regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "down regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down regulation of SOD" RELATED [GOC:TermGenie] +synonym: "down regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "down regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "down regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "down regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "down regulation of SODF" RELATED [GOC:TermGenie] +synonym: "down regulation of SODS" RELATED [GOC:TermGenie] +synonym: "down regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "down regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "down regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down-regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "down-regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "down-regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "down-regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "down-regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "down-regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "down-regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "down-regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down-regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down-regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "down-regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "down-regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "down-regulation of SOD" RELATED [GOC:TermGenie] +synonym: "down-regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "down-regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "down-regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "down-regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "down-regulation of SODF" RELATED [GOC:TermGenie] +synonym: "down-regulation of SODS" RELATED [GOC:TermGenie] +synonym: "down-regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "down-regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "down-regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "downregulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "downregulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cuprein" RELATED [GOC:TermGenie] +synonym: "downregulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "downregulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "downregulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "downregulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "downregulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "downregulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "downregulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "downregulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "downregulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "downregulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "downregulation of SOD" RELATED [GOC:TermGenie] +synonym: "downregulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "downregulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "downregulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "downregulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "downregulation of SODF" RELATED [GOC:TermGenie] +synonym: "downregulation of SODS" RELATED [GOC:TermGenie] +synonym: "downregulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "downregulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "downregulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "inhibition of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "inhibition of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cuprein" RELATED [GOC:TermGenie] +synonym: "inhibition of cytocuprein" RELATED [GOC:TermGenie] +synonym: "inhibition of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "inhibition of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "inhibition of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hemocuprein" RELATED [GOC:TermGenie] +synonym: "inhibition of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "inhibition of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "inhibition of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "inhibition of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "inhibition of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "inhibition of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "inhibition of SOD" RELATED [GOC:TermGenie] +synonym: "inhibition of SOD-1" RELATED [GOC:TermGenie] +synonym: "inhibition of SOD-2" RELATED [GOC:TermGenie] +synonym: "inhibition of SOD-3" RELATED [GOC:TermGenie] +synonym: "inhibition of SOD-4" RELATED [GOC:TermGenie] +synonym: "inhibition of SODF" RELATED [GOC:TermGenie] +synonym: "inhibition of SODS" RELATED [GOC:TermGenie] +synonym: "inhibition of superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "inhibition of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "inhibition of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "negative regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "negative regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "negative regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "negative regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "negative regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "negative regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "negative regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "negative regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "negative regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "negative regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "negative regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "negative regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "negative regulation of SOD" RELATED [GOC:TermGenie] +synonym: "negative regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "negative regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "negative regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "negative regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "negative regulation of SODF" RELATED [GOC:TermGenie] +synonym: "negative regulation of SODS" RELATED [GOC:TermGenie] +synonym: "negative regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "negative regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "negative regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1901668 ! regulation of superoxide dismutase activity +is_a: GO:1904832 ! negative regulation of removal of superoxide radicals +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004784 ! superoxide dismutase activity +relationship: negatively_regulates GO:0004784 ! superoxide dismutase activity +created_by: tb +creation_date: 2012-11-21T21:36:07Z + +[Term] +id: GO:1901671 +name: positive regulation of superoxide dismutase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] +synonym: "activation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "activation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of cuprein" RELATED [GOC:TermGenie] +synonym: "activation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "activation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "activation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "activation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "activation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "activation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "activation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "activation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "activation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "activation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "activation of SOD" RELATED [GOC:TermGenie] +synonym: "activation of SOD-1" RELATED [GOC:TermGenie] +synonym: "activation of SOD-2" RELATED [GOC:TermGenie] +synonym: "activation of SOD-3" RELATED [GOC:TermGenie] +synonym: "activation of SOD-4" RELATED [GOC:TermGenie] +synonym: "activation of SODF" RELATED [GOC:TermGenie] +synonym: "activation of SODS" RELATED [GOC:TermGenie] +synonym: "activation of superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "activation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "activation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "activation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "activation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "positive regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "positive regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "positive regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "positive regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "positive regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "positive regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "positive regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "positive regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "positive regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "positive regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "positive regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "positive regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "positive regulation of SOD" RELATED [GOC:TermGenie] +synonym: "positive regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "positive regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "positive regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "positive regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "positive regulation of SODF" RELATED [GOC:TermGenie] +synonym: "positive regulation of SODS" RELATED [GOC:TermGenie] +synonym: "positive regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "positive regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "positive regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "up regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "up regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "up regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "up regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "up regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "up regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "up regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "up regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "up regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up regulation of SOD" RELATED [GOC:TermGenie] +synonym: "up regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "up regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "up regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "up regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "up regulation of SODF" RELATED [GOC:TermGenie] +synonym: "up regulation of SODS" RELATED [GOC:TermGenie] +synonym: "up regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "up regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "up regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up-regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "up-regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cuprein" RELATED [GOC:TermGenie] +synonym: "up-regulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "up-regulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "up-regulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "up-regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "up-regulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "up-regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up-regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up-regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "up-regulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "up-regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "up-regulation of SOD" RELATED [GOC:TermGenie] +synonym: "up-regulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "up-regulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "up-regulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "up-regulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "up-regulation of SODF" RELATED [GOC:TermGenie] +synonym: "up-regulation of SODS" RELATED [GOC:TermGenie] +synonym: "up-regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "up-regulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "up-regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "upregulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] +synonym: "upregulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cuprein" RELATED [GOC:TermGenie] +synonym: "upregulation of cytocuprein" RELATED [GOC:TermGenie] +synonym: "upregulation of erythrocuprein" RELATED [GOC:TermGenie] +synonym: "upregulation of Fe-SOD" RELATED [GOC:TermGenie] +synonym: "upregulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hemocuprein" RELATED [GOC:TermGenie] +synonym: "upregulation of hepatocuprein" RELATED [GOC:TermGenie] +synonym: "upregulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "upregulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "upregulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] +synonym: "upregulation of Mn-SOD" RELATED [GOC:TermGenie] +synonym: "upregulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] +synonym: "upregulation of SOD" RELATED [GOC:TermGenie] +synonym: "upregulation of SOD-1" RELATED [GOC:TermGenie] +synonym: "upregulation of SOD-2" RELATED [GOC:TermGenie] +synonym: "upregulation of SOD-3" RELATED [GOC:TermGenie] +synonym: "upregulation of SOD-4" RELATED [GOC:TermGenie] +synonym: "upregulation of SODF" RELATED [GOC:TermGenie] +synonym: "upregulation of SODS" RELATED [GOC:TermGenie] +synonym: "upregulation of superoxide dismutase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of superoxide dismutase I" RELATED [GOC:TermGenie] +synonym: "upregulation of superoxide dismutase II" RELATED [GOC:TermGenie] +synonym: "upregulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1901668 ! regulation of superoxide dismutase activity +is_a: GO:1904833 ! positive regulation of removal of superoxide radicals +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004784 ! superoxide dismutase activity +relationship: positively_regulates GO:0004784 ! superoxide dismutase activity +created_by: tb +creation_date: 2012-11-21T21:36:11Z + +[Term] +id: GO:1901672 +name: positive regulation of systemic acquired resistance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of systemic acquired resistance." [GOC:TermGenie] +synonym: "activation of salicylic acid-dependent systemic resistance" EXACT [GOC:TermGenie] +synonym: "activation of systemic acquired resistance" NARROW [GOC:TermGenie] +synonym: "positive regulation of salicylic acid-dependent systemic resistance" EXACT [GOC:TermGenie] +synonym: "up regulation of salicylic acid-dependent systemic resistance" EXACT [GOC:TermGenie] +synonym: "up regulation of systemic acquired resistance" EXACT [GOC:TermGenie] +synonym: "up-regulation of salicylic acid-dependent systemic resistance" EXACT [GOC:TermGenie] +synonym: "up-regulation of systemic acquired resistance" EXACT [GOC:TermGenie] +synonym: "upregulation of salicylic acid-dependent systemic resistance" EXACT [GOC:TermGenie] +synonym: "upregulation of systemic acquired resistance" EXACT [GOC:TermGenie] +is_a: GO:0010112 ! regulation of systemic acquired resistance +is_a: GO:0045089 ! positive regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009627 ! systemic acquired resistance +relationship: positively_regulates GO:0009627 ! systemic acquired resistance +created_by: tb +creation_date: 2012-11-21T22:03:58Z + +[Term] +id: GO:1901673 +name: regulation of mitotic spindle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic spindle assembly." [GOC:TermGenie] +synonym: "regulation of spindle assembly involved in mitosis" EXACT [] +is_a: GO:0007088 ! regulation of mitotic nuclear division +is_a: GO:0060236 ! regulation of mitotic spindle organization +is_a: GO:0090169 ! regulation of spindle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090307 ! mitotic spindle assembly +relationship: regulates GO:0090307 ! mitotic spindle assembly +created_by: al +creation_date: 2012-11-22T09:50:00Z + +[Term] +id: GO:1901674 +name: regulation of histone H3-K27 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation." [GOC:BHF, GOC:TermGenie] +synonym: "regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043974 ! histone H3-K27 acetylation +relationship: regulates GO:0043974 ! histone H3-K27 acetylation +created_by: vk +creation_date: 2012-11-22T12:06:31Z + +[Term] +id: GO:1901675 +name: negative regulation of histone H3-K27 acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation." [GOC:BHF, GOC:TermGenie] +synonym: "down regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3-K27 acetylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:1901674 ! regulation of histone H3-K27 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043974 ! histone H3-K27 acetylation +relationship: negatively_regulates GO:0043974 ! histone H3-K27 acetylation +created_by: vk +creation_date: 2012-11-22T12:06:40Z + +[Term] +id: GO:1901676 +name: positive regulation of histone H3-K27 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation." [GOC:BHF, GOC:TermGenie] +synonym: "activation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "activation of histone H3-K27 acetylation" NARROW [GOC:TermGenie] +synonym: "activation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3 acetylation at K27" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K27 acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3K27 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:1901674 ! regulation of histone H3-K27 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043974 ! histone H3-K27 acetylation +relationship: positively_regulates GO:0043974 ! histone H3-K27 acetylation +created_by: vk +creation_date: 2012-11-22T12:06:45Z + +[Term] +id: GO:1901678 +name: iron coordination entity transport +namespace: biological_process +def: "The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:pr, GOC:TermGenie] +is_a: GO:0006826 ! iron ion transport +created_by: pr +creation_date: 2012-11-22T15:43:15Z + +[Term] +id: GO:1901679 +name: nucleotide transmembrane transport +namespace: biological_process +def: "The directed movement of nucleotide across a membrane." [GOC:pr, GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +synonym: "nucleotide membrane transport" EXACT [] +is_a: GO:0006862 ! nucleotide transport +is_a: GO:0055085 ! transmembrane transport +created_by: pr +creation_date: 2012-11-22T15:43:23Z + +[Term] +id: GO:1901680 +name: sulfur-containing amino acid secondary active transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:pr, GOC:TermGenie] +is_a: GO:0000099 ! sulfur amino acid transmembrane transporter activity +is_a: GO:0015291 ! secondary active transmembrane transporter activity +is_a: GO:0022853 ! active ion transmembrane transporter activity +created_by: pr +creation_date: 2012-11-22T16:16:48Z + +[Term] +id: GO:1901681 +name: sulfur compound binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a sulfur compound." [GOC:pr, GOC:TermGenie] +synonym: "sulfur molecular entity binding" EXACT [] +is_a: GO:0005488 ! binding +created_by: pr +creation_date: 2012-11-26T20:45:23Z + +[Term] +id: GO:1901682 +name: sulfur compound transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] +is_a: GO:0022857 ! transmembrane transporter activity +created_by: pr +creation_date: 2012-11-26T20:45:29Z + +[Term] +id: GO:1901683 +name: arsenate ion transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of an arsenate ion from one side of a membrane to the other." [GOC:TermGenie] +is_a: GO:0008509 ! anion transmembrane transporter activity +is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity +relationship: part_of GO:1901684 ! arsenate ion transmembrane transport +created_by: tb +creation_date: 2012-12-04T23:26:27Z + +[Term] +id: GO:1901684 +name: arsenate ion transmembrane transport +namespace: biological_process +def: "The process in which arsenate is transported across a membrane." [GOC:TermGenie] +comment: Note that this term is not intended for use in annotating lateral movement within membranes. +is_a: GO:0098656 ! anion transmembrane transport +created_by: tb +creation_date: 2012-12-04T23:26:36Z + +[Term] +id: GO:1901685 +name: glutathione derivative metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glutathione derivative." [GOC:pr, GOC:TermGenie] +synonym: "glutathione derivative metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: pr +creation_date: 2012-12-05T11:57:11Z + +[Term] +id: GO:1901686 +name: glutathione derivative catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glutathione derivative." [GOC:pr, GOC:TermGenie] +synonym: "glutathione derivative breakdown" EXACT [GOC:TermGenie] +synonym: "glutathione derivative catabolism" EXACT [GOC:TermGenie] +synonym: "glutathione derivative degradation" EXACT [GOC:TermGenie] +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901685 ! glutathione derivative metabolic process +created_by: pr +creation_date: 2012-12-05T11:57:16Z + +[Term] +id: GO:1901687 +name: glutathione derivative biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glutathione derivative." [GOC:pr, GOC:TermGenie] +synonym: "glutathione derivative anabolism" EXACT [GOC:TermGenie] +synonym: "glutathione derivative biosynthesis" EXACT [GOC:TermGenie] +synonym: "glutathione derivative formation" EXACT [GOC:TermGenie] +synonym: "glutathione derivative synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901685 ! glutathione derivative metabolic process +created_by: pr +creation_date: 2012-12-05T11:57:20Z + +[Term] +id: GO:1901691 +name: proton binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with proton." [GOC:TermGenie] +synonym: "hydrogen ion binding" EXACT [GOC:bm] +is_a: GO:0043169 ! cation binding +created_by: al +creation_date: 2012-12-07T13:50:53Z + +[Term] +id: GO:1901692 +name: regulation of compound eye retinal cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990010 ! compound eye retinal cell apoptotic process +relationship: regulates GO:1990010 ! compound eye retinal cell apoptotic process +created_by: pr +creation_date: 2012-12-12T10:28:35Z + +[Term] +id: GO:1901693 +name: negative regulation of compound eye retinal cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] +synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process +relationship: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process +created_by: pr +creation_date: 2012-12-12T10:28:40Z + +[Term] +id: GO:1901694 +name: positive regulation of compound eye retinal cell apoptotic process +namespace: biological_process +alt_id: GO:0046675 +def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] +synonym: "activation of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "induction of compound eye retinal cell programmed cell death" RELATED [] +synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death +is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process +relationship: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process +created_by: pr +creation_date: 2012-12-12T10:28:45Z + +[Term] +id: GO:1901695 +name: tyramine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tyramine." [GOC:TermGenie, PMID:21284755] +synonym: "tyramine anabolism" EXACT [GOC:TermGenie] +synonym: "tyramine biosynthesis" EXACT [GOC:TermGenie] +synonym: "tyramine formation" EXACT [GOC:TermGenie] +synonym: "tyramine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042136 ! neurotransmitter biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901162 ! primary amino compound biosynthetic process +created_by: tb +creation_date: 2012-12-12T19:31:35Z + +[Term] +id: GO:1901696 +name: cannabinoid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cannabinoid." [GOC:TermGenie] +synonym: "cannabinoid anabolism" EXACT [GOC:TermGenie] +synonym: "cannabinoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "cannabinoid formation" EXACT [GOC:TermGenie] +synonym: "cannabinoid synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901576 ! organic substance biosynthetic process +created_by: ms +creation_date: 2012-12-13T08:07:47Z + +[Term] +id: GO:1901697 +name: olivetolic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of olivetolic acid." [GOC:TermGenie] +synonym: "olivetolic acid anabolism" EXACT [GOC:TermGenie] +synonym: "olivetolic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "olivetolic acid formation" EXACT [GOC:TermGenie] +synonym: "olivetolic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +created_by: ms +creation_date: 2012-12-13T08:07:51Z + +[Term] +id: GO:1901698 +name: response to nitrogen compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] +synonym: "response to nitrogen molecular entity" EXACT [] +is_a: GO:0042221 ! response to chemical +created_by: pr +creation_date: 2012-12-13T15:06:08Z + +[Term] +id: GO:1901699 +name: cellular response to nitrogen compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] +synonym: "cellular response to nitrogen molecular entity" EXACT [] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1901698 ! response to nitrogen compound +created_by: pr +creation_date: 2012-12-13T15:06:13Z + +[Term] +id: GO:1901700 +name: response to oxygen-containing compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] +synonym: "response to oxygen molecular entity" EXACT [] +is_a: GO:0042221 ! response to chemical +created_by: pr +creation_date: 2012-12-13T15:11:37Z + +[Term] +id: GO:1901701 +name: cellular response to oxygen-containing compound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] +synonym: "cellular response to oxygen molecular entity" EXACT [] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2012-12-13T15:11:42Z + +[Term] +id: GO:1901702 +name: salt transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +is_a: GO:0008324 ! cation transmembrane transporter activity +is_a: GO:0008509 ! anion transmembrane transporter activity +created_by: pr +creation_date: 2012-12-13T15:14:47Z + +[Term] +id: GO:1901703 +name: protein localization involved in auxin polar transport +namespace: biological_process +def: "Any protein localization that is involved in auxin polar transport." [GOC:TermGenie, PMID:23163883] +synonym: "establishment and maintenance of protein localization involved in auxin polar transport" EXACT [GOC:TermGenie] +synonym: "protein localisation involved in auxin polar transport" EXACT [GOC:TermGenie] +is_a: GO:0008104 ! protein localization +intersection_of: GO:0008104 ! protein localization +intersection_of: part_of GO:0009926 ! auxin polar transport +relationship: part_of GO:0009926 ! auxin polar transport +created_by: tb +creation_date: 2012-12-13T19:06:13Z + +[Term] +id: GO:1901704 +name: L-glutamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-glutamine." [GOC:TermGenie] +synonym: "L-glutamine anabolism" EXACT [GOC:TermGenie] +synonym: "L-glutamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "L-glutamine formation" EXACT [GOC:TermGenie] +synonym: "L-glutamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006542 ! glutamine biosynthetic process +is_a: GO:0017144 ! drug metabolic process +created_by: pde +creation_date: 2012-12-13T23:32:52Z + +[Term] +id: GO:1901705 +name: L-isoleucine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-isoleucine." [GOC:TermGenie] +synonym: "L-isoleucine anabolism" EXACT [GOC:TermGenie] +synonym: "L-isoleucine biosynthesis" EXACT [GOC:TermGenie] +synonym: "L-isoleucine formation" EXACT [GOC:TermGenie] +synonym: "L-isoleucine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009067 ! aspartate family amino acid biosynthetic process +is_a: GO:0009097 ! isoleucine biosynthetic process +created_by: pde +creation_date: 2012-12-13T23:32:56Z + +[Term] +id: GO:1901706 +name: mesenchymal cell differentiation involved in bone development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217] +is_a: GO:0048762 ! mesenchymal cell differentiation +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0060348 ! bone development +relationship: part_of GO:0060348 ! bone development +created_by: hjd +creation_date: 2012-12-14T16:04:16Z + +[Term] +id: GO:1901707 +name: leptomycin B binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with leptomycin B." [GOC:TermGenie] +is_a: GO:0005504 ! fatty acid binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mah +creation_date: 2012-12-18T15:10:04Z + +[Term] +id: GO:1901708 +name: (+)-3'-hydroxylarreatricin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin." [GOC:TermGenie, pmid:12960376] +synonym: "(+)-3'-hydroxylarreatricin anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-3'-hydroxylarreatricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-3'-hydroxylarreatricin formation" EXACT [GOC:TermGenie] +synonym: "(+)-3'-hydroxylarreatricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +created_by: ms +creation_date: 2012-12-19T14:39:32Z + +[Term] +id: GO:1901709 +name: (+)-larreatricin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-larreatricin." [GOC:TermGenie, pmid:12960376] +synonym: "(+)-larreatricin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: ms +creation_date: 2012-12-19T14:44:29Z + +[Term] +id: GO:1901710 +name: regulation of homoserine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of homoserine biosynthetic process." [GOC:TermGenie] +synonym: "regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "regulation of homoserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009090 ! homoserine biosynthetic process +relationship: regulates GO:0009090 ! homoserine biosynthetic process +created_by: mcc +creation_date: 2012-12-19T16:01:56Z + +[Term] +id: GO:1901711 +name: negative regulation of homoserine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process." [GOC:TermGenie] +synonym: "down regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of homoserine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of homoserine formation" EXACT [GOC:TermGenie] +synonym: "inhibition of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of homoserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901710 ! regulation of homoserine biosynthetic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009090 ! homoserine biosynthetic process +relationship: negatively_regulates GO:0009090 ! homoserine biosynthetic process +created_by: mcc +creation_date: 2012-12-19T16:02:00Z + +[Term] +id: GO:1901712 +name: positive regulation of homoserine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process." [GOC:TermGenie] +synonym: "activation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "activation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of homoserine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "activation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of homoserine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of homoserine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of homoserine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of homoserine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of homoserine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of homoserine synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901710 ! regulation of homoserine biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009090 ! homoserine biosynthetic process +relationship: positively_regulates GO:0009090 ! homoserine biosynthetic process +created_by: mcc +creation_date: 2012-12-19T16:02:05Z + +[Term] +id: GO:1901713 +name: negative regulation of urea catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process." [GOC:TermGenie] +synonym: "down regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "down regulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "down-regulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "downregulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of urea breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of urea catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of urea catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of urea decomposition" EXACT [GOC:TermGenie] +synonym: "inhibition of urea degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "negative regulation of urea degradation" EXACT [GOC:TermGenie] +is_a: GO:0034252 ! negative regulation of cellular amide catabolic process +is_a: GO:0034254 ! regulation of urea catabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1903315 ! negative regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043419 ! urea catabolic process +relationship: negatively_regulates GO:0043419 ! urea catabolic process +created_by: mcc +creation_date: 2012-12-19T16:12:13Z + +[Term] +id: GO:1901714 +name: positive regulation of urea catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of urea catabolic process." [GOC:TermGenie] +synonym: "activation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "activation of urea catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "activation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "activation of urea degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "positive regulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "up regulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of urea breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of urea catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of urea catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of urea decomposition" EXACT [GOC:TermGenie] +synonym: "upregulation of urea degradation" EXACT [GOC:TermGenie] +is_a: GO:0034253 ! positive regulation of cellular amide catabolic process +is_a: GO:0034254 ! regulation of urea catabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1903316 ! positive regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043419 ! urea catabolic process +relationship: positively_regulates GO:0043419 ! urea catabolic process +created_by: mcc +creation_date: 2012-12-19T16:12:18Z + +[Term] +id: GO:1901715 +name: regulation of gamma-aminobutyric acid catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process." [GOC:TermGenie] +synonym: "regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +relationship: regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +created_by: mcc +creation_date: 2012-12-19T16:13:24Z + +[Term] +id: GO:1901716 +name: negative regulation of gamma-aminobutyric acid catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process." [GOC:TermGenie] +synonym: "down regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of gamma-aminobutyric acid catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:1901715 ! regulation of gamma-aminobutyric acid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +relationship: negatively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +created_by: mcc +creation_date: 2012-12-19T16:13:31Z + +[Term] +id: GO:1901717 +name: positive regulation of gamma-aminobutyric acid catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process." [GOC:TermGenie] +synonym: "activation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "activation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "activation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "activation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "activation of gamma-aminobutyric acid catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "activation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of 4-aminobutanoate catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 4-aminobutanoate catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 4-aminobutyrate catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 4-aminobutyrate catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of GABA catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of GABA catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of gamma-aminobutyric acid breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of gamma-aminobutyric acid catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:1901715 ! regulation of gamma-aminobutyric acid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +relationship: positively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process +created_by: mcc +creation_date: 2012-12-19T16:13:36Z + +[Term] +id: GO:1901718 +name: obsolete regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport." [GOC:TermGenie, GOC:vw] +comment: The term was obsoleted because it is better represented by a GO-CAM model. +is_obsolete: true +created_by: pr +creation_date: 2012-12-19T17:04:04Z + +[Term] +id: GO:1901719 +name: regulation of NMS complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation." [GOC:TermGenie, GOC:vw, PMID:22561345] +synonym: "regulation of KMN complex assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "regulation of NMS complex assembly involved in kinetochore assembly" EXACT [] +synonym: "regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +is_a: GO:0090234 ! regulation of kinetochore assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044768 ! NMS complex assembly +relationship: regulates GO:0044768 ! NMS complex assembly +created_by: jl +creation_date: 2012-12-20T11:44:17Z + +[Term] +id: GO:1901720 +name: negative regulation of NMS complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation." [GOC:TermGenie, GOC:vw, PMID:22561345] +synonym: "down regulation of KMN complex assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down regulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "downregulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "downregulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "downregulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "downregulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "inhibition of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "inhibition of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "inhibition of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "inhibition of NMS complex interaction involved in chromosome segregation" NARROW [GOC:TermGenie] +synonym: "negative regulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "negative regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "negative regulation of NMS complex assembly involved in kinetochore assembly" EXACT [] +synonym: "negative regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +is_a: GO:1901719 ! regulation of NMS complex assembly +is_a: GO:1905560 ! negative regulation of kinetochore assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044768 ! NMS complex assembly +relationship: negatively_regulates GO:0044768 ! NMS complex assembly +created_by: jl +creation_date: 2012-12-20T11:44:22Z + +[Term] +id: GO:1901721 +name: positive regulation of NMS complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation." [GOC:TermGenie, GOC:vw, PMID:22561345] +synonym: "activation of KMN complex assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "activation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "activation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "activation of NMS complex interaction involved in chromosome segregation" NARROW [GOC:TermGenie] +synonym: "positive regulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "positive regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "positive regulation of NMS complex assembly involved in kinetochore assembly" EXACT [] +synonym: "positive regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of KMN complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of KMN network assembly involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of NMS complex association involved in chromosome segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of NMS complex interaction involved in chromosome segregation" EXACT [GOC:TermGenie] +is_a: GO:1901719 ! regulation of NMS complex assembly +is_a: GO:1905561 ! positive regulation of kinetochore assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044768 ! NMS complex assembly +relationship: positively_regulates GO:0044768 ! NMS complex assembly +created_by: jl +creation_date: 2012-12-20T11:44:26Z + +[Term] +id: GO:1901722 +name: regulation of cell proliferation involved in kidney development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072111 ! cell proliferation involved in kidney development +relationship: regulates GO:0072111 ! cell proliferation involved in kidney development +created_by: krc +creation_date: 2012-12-27T19:30:31Z + +[Term] +id: GO:1901723 +name: negative regulation of cell proliferation involved in kidney development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] +synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +synonym: "inhibition of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development +relationship: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development +created_by: krc +creation_date: 2012-12-27T19:30:35Z + +[Term] +id: GO:1901724 +name: positive regulation of cell proliferation involved in kidney development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] +synonym: "activation of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] +synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072111 ! cell proliferation involved in kidney development +relationship: positively_regulates GO:0072111 ! cell proliferation involved in kidney development +created_by: krc +creation_date: 2012-12-27T19:30:40Z + +[Term] +id: GO:1901725 +name: regulation of histone deacetylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone deacetylase activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +is_a: GO:0031063 ! regulation of histone deacetylation +is_a: GO:0150065 ! regulation of deacetylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004407 ! histone deacetylase activity +relationship: regulates GO:0004407 ! histone deacetylase activity +created_by: rl +creation_date: 2013-01-07T09:14:12Z + +[Term] +id: GO:1901726 +name: negative regulation of histone deacetylase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +synonym: "down regulation of histone deacetylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone deacetylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of histone deacetylase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of histone deacetylase activity" NARROW [GOC:TermGenie] +is_a: GO:0031064 ! negative regulation of histone deacetylation +is_a: GO:0150066 ! negative regulation of deacetylase activity +is_a: GO:1901725 ! regulation of histone deacetylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004407 ! histone deacetylase activity +relationship: negatively_regulates GO:0004407 ! histone deacetylase activity +created_by: rl +creation_date: 2013-01-07T09:14:17Z + +[Term] +id: GO:1901727 +name: positive regulation of histone deacetylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone deacetylase activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +synonym: "activation of histone deacetylase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of histone deacetylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone deacetylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of histone deacetylase activity" EXACT [GOC:TermGenie] +is_a: GO:0031065 ! positive regulation of histone deacetylation +is_a: GO:0090045 ! positive regulation of deacetylase activity +is_a: GO:1901725 ! regulation of histone deacetylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004407 ! histone deacetylase activity +relationship: positively_regulates GO:0004407 ! histone deacetylase activity +created_by: rl +creation_date: 2013-01-07T09:14:21Z + +[Term] +id: GO:1901728 +name: monensin A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monensin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00178] +synonym: "monensin A metabolism" EXACT [GOC:TermGenie] +synonym: "monensin metabolism" EXACT [GOC:yaf] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: yaf +creation_date: 2013-01-09T11:55:45Z + +[Term] +id: GO:1901729 +name: monensin A catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monensin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00178] +synonym: "monensin A breakdown" EXACT [GOC:TermGenie] +synonym: "monensin A catabolism" EXACT [GOC:TermGenie] +synonym: "monensin A degradation" EXACT [GOC:TermGenie] +synonym: "monensin breakdown" EXACT [GOC:yaf] +synonym: "monensin catabolism" EXACT [GOC:yaf] +synonym: "monensin degradation" EXACT [GOC:yaf] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901728 ! monensin A metabolic process +created_by: yaf +creation_date: 2013-01-09T11:55:49Z + +[Term] +id: GO:1901730 +name: monensin A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monensin A." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00178] +synonym: "monensin A anabolism" EXACT [GOC:TermGenie] +synonym: "monensin A biosynthesis" EXACT [GOC:TermGenie] +synonym: "monensin A formation" EXACT [GOC:TermGenie] +synonym: "monensin A synthesis" EXACT [GOC:TermGenie] +synonym: "monensin anabolism" EXACT [GOC:yaf] +synonym: "monensin biosynthesis" EXACT [GOC:yaf] +synonym: "monensin formation" EXACT [GOC:yaf] +synonym: "monensin synthesis" EXACT [GOC:yaf] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901728 ! monensin A metabolic process +created_by: yaf +creation_date: 2013-01-09T11:55:53Z + +[Term] +id: GO:1901731 +name: positive regulation of platelet aggregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules." [GOC:fj, GOC:TermGenie] +synonym: "activation of blood platelet aggregation" NARROW [GOC:TermGenie] +synonym: "activation of platelet aggregation" NARROW [GOC:TermGenie] +synonym: "activation of thrombocyte aggregation" RELATED [GOC:TermGenie] +synonym: "positive regulation of blood platelet aggregation" EXACT [GOC:TermGenie] +synonym: "positive regulation of thrombocyte aggregation" RELATED [GOC:TermGenie] +synonym: "up regulation of blood platelet aggregation" EXACT [GOC:TermGenie] +synonym: "up regulation of platelet aggregation" EXACT [GOC:TermGenie] +synonym: "up regulation of thrombocyte aggregation" RELATED [GOC:TermGenie] +synonym: "up-regulation of blood platelet aggregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of platelet aggregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of thrombocyte aggregation" RELATED [GOC:TermGenie] +synonym: "upregulation of blood platelet aggregation" EXACT [GOC:TermGenie] +synonym: "upregulation of platelet aggregation" EXACT [GOC:TermGenie] +synonym: "upregulation of thrombocyte aggregation" RELATED [GOC:TermGenie] +is_a: GO:0010572 ! positive regulation of platelet activation +is_a: GO:0034112 ! positive regulation of homotypic cell-cell adhesion +is_a: GO:0090330 ! regulation of platelet aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070527 ! platelet aggregation +relationship: positively_regulates GO:0070527 ! platelet aggregation +created_by: pr +creation_date: 2013-01-10T13:25:39Z + +[Term] +id: GO:1901732 +name: quercetin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving quercetin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00724] +synonym: "quercetin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0051552 ! flavone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: yaf +creation_date: 2013-01-11T10:25:11Z + +[Term] +id: GO:1901733 +name: quercetin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of quercetin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00724] +synonym: "quercetin breakdown" EXACT [GOC:TermGenie] +synonym: "quercetin catabolism" EXACT [GOC:TermGenie] +synonym: "quercetin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046275 ! flavonoid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +is_a: GO:1901732 ! quercetin metabolic process +created_by: yaf +creation_date: 2013-01-11T10:25:15Z + +[Term] +id: GO:1901734 +name: quercetin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of quercetin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00724] +synonym: "quercetin anabolism" EXACT [GOC:TermGenie] +synonym: "quercetin biosynthesis" EXACT [GOC:TermGenie] +synonym: "quercetin formation" EXACT [GOC:TermGenie] +synonym: "quercetin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0051553 ! flavone biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1901732 ! quercetin metabolic process +created_by: yaf +creation_date: 2013-01-11T10:25:20Z + +[Term] +id: GO:1901735 +name: (R)-mevalonic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (R)-mevalonic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00058] +synonym: "(R) mevalonate metabolism" EXACT [GOC:yaf] +synonym: "(R)-mevalonic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: yaf +creation_date: 2013-01-11T11:25:50Z + +[Term] +id: GO:1901736 +name: (R)-mevalonic acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00058] +synonym: "(R)-mevalonate breakdown" EXACT [MetaCyc:PWY-5074] +synonym: "(R)-mevalonate catabolism" EXACT [MetaCyc:PWY-5074] +synonym: "(R)-mevalonate degradation" EXACT [MetaCyc:PWY-5074] +synonym: "(R)-mevalonic acid breakdown" EXACT [GOC:TermGenie] +synonym: "(R)-mevalonic acid catabolism" EXACT [GOC:TermGenie] +synonym: "(R)-mevalonic acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +is_a: GO:1901735 ! (R)-mevalonic acid metabolic process +created_by: yaf +creation_date: 2013-01-11T11:25:55Z + +[Term] +id: GO:1901737 +name: (R)-mevalonic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00058] +synonym: "(R)-mevalonate anabolism" EXACT [GOC:yaf] +synonym: "(R)-mevalonate biosynthesis" EXACT [GOC:yaf] +synonym: "(R)-mevalonate synthesis" EXACT [GOC:yaf] +synonym: "(R)-mevalonic acid anabolism" EXACT [GOC:TermGenie] +synonym: "(R)-mevalonic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "(R)-mevalonic acid formation" EXACT [GOC:TermGenie] +synonym: "(R)-mevalonic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1901735 ! (R)-mevalonic acid metabolic process +created_by: yaf +creation_date: 2013-01-11T11:25:59Z + +[Term] +id: GO:1901738 +name: regulation of vitamin A metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vitamin A metabolic process." [GOC:TermGenie, PMID:18093975] +synonym: "regulation of vitamin A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0030656 ! regulation of vitamin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006776 ! vitamin A metabolic process +relationship: regulates GO:0006776 ! vitamin A metabolic process +created_by: dph +creation_date: 2013-01-11T15:29:43Z + +[Term] +id: GO:1901739 +name: regulation of myoblast fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myoblast fusion." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21364645] +is_a: GO:0010830 ! regulation of myotube differentiation +is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007520 ! myoblast fusion +relationship: regulates GO:0007520 ! myoblast fusion +created_by: rl +creation_date: 2013-01-11T20:23:50Z + +[Term] +id: GO:1901740 +name: negative regulation of myoblast fusion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21364645] +synonym: "down regulation of myoblast fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of myoblast fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of myoblast fusion" EXACT [GOC:TermGenie] +synonym: "inhibition of myoblast fusion" NARROW [GOC:TermGenie] +is_a: GO:0010832 ! negative regulation of myotube differentiation +is_a: GO:0034242 ! negative regulation of syncytium formation by plasma membrane fusion +is_a: GO:1901739 ! regulation of myoblast fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007520 ! myoblast fusion +relationship: negatively_regulates GO:0007520 ! myoblast fusion +created_by: rl +creation_date: 2013-01-11T20:23:55Z + +[Term] +id: GO:1901741 +name: positive regulation of myoblast fusion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myoblast fusion." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21364645] +synonym: "activation of myoblast fusion" NARROW [GOC:TermGenie] +synonym: "up regulation of myoblast fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of myoblast fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of myoblast fusion" EXACT [GOC:TermGenie] +is_a: GO:0010831 ! positive regulation of myotube differentiation +is_a: GO:0060143 ! positive regulation of syncytium formation by plasma membrane fusion +is_a: GO:1901739 ! regulation of myoblast fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007520 ! myoblast fusion +relationship: positively_regulates GO:0007520 ! myoblast fusion +created_by: rl +creation_date: 2013-01-11T20:24:03Z + +[Term] +id: GO:1901742 +name: 2-deoxystreptamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-deoxystreptamine." [GOC:TermGenie, GOC:yaf] +synonym: "2-deoxystreptamine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0019751 ! polyol metabolic process +created_by: yaf +creation_date: 2013-01-14T10:01:57Z + +[Term] +id: GO:1901743 +name: 2-deoxystreptamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine." [GOC:TermGenie, GOC:yaf] +synonym: "2-deoxystreptamine breakdown" EXACT [GOC:TermGenie] +synonym: "2-deoxystreptamine catabolism" EXACT [GOC:TermGenie] +synonym: "2-deoxystreptamine degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901742 ! 2-deoxystreptamine metabolic process +created_by: yaf +creation_date: 2013-01-14T10:02:01Z + +[Term] +id: GO:1901744 +name: 2-deoxystreptamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00907] +synonym: "2-deoxystreptamine anabolism" EXACT [GOC:TermGenie] +synonym: "2-deoxystreptamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "2-deoxystreptamine formation" EXACT [GOC:TermGenie] +synonym: "2-deoxystreptamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901742 ! 2-deoxystreptamine metabolic process +created_by: yaf +creation_date: 2013-01-14T10:02:06Z + +[Term] +id: GO:1901745 +name: prephenate(2-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving prephenate(2-)." [GOC:TermGenie, GOC:yaf, PMID:16752890] +synonym: "prephenate metabolism" EXACT [GOC:yaf] +synonym: "prephenate(2-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043648 ! dicarboxylic acid metabolic process +created_by: yaf +creation_date: 2013-01-14T10:13:49Z + +[Term] +id: GO:1901746 +name: prephenate(2-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prephenate(2-)." [GOC:TermGenie, GOC:yaf, PMID:16752890] +synonym: "prephenate breakdown" EXACT [GOC:yaf] +synonym: "prephenate catabolism" EXACT [GOC:yaf] +synonym: "prephenate degradation" EXACT [GOC:yaf] +synonym: "prephenate(2-) breakdown" EXACT [GOC:TermGenie] +synonym: "prephenate(2-) catabolism" EXACT [GOC:TermGenie] +synonym: "prephenate(2-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0043649 ! dicarboxylic acid catabolic process +is_a: GO:1901745 ! prephenate(2-) metabolic process +created_by: yaf +creation_date: 2013-01-14T10:13:53Z + +[Term] +id: GO:1901747 +name: prephenate(2-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of prephenate(2-)." [GOC:TermGenie, GOC:yaf, PMID:16752890, UniPathway:UPA00120] +synonym: "prephenate anabolism" EXACT [GOC:yaf] +synonym: "prephenate biosynthesis" EXACT [GOC:yaf] +synonym: "prephenate formation" EXACT [GOC:yaf] +synonym: "prephenate synthesis" EXACT [GOC:yaf] +synonym: "prephenate(2-) anabolism" EXACT [GOC:TermGenie] +synonym: "prephenate(2-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "prephenate(2-) formation" EXACT [GOC:TermGenie] +synonym: "prephenate(2-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043650 ! dicarboxylic acid biosynthetic process +is_a: GO:1901745 ! prephenate(2-) metabolic process +created_by: yaf +creation_date: 2013-01-14T10:13:57Z + +[Term] +id: GO:1901748 +name: leukotriene D4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leukotriene D4." [GOC:TermGenie, GOC:yaf] +synonym: "leukotriene D4 metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0006691 ! leukotriene metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0017144 ! drug metabolic process +created_by: yaf +creation_date: 2013-01-14T10:56:12Z + +[Term] +id: GO:1901749 +name: leukotriene D4 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of leukotriene D4." [GOC:TermGenie, GOC:yaf] +synonym: "leukotriene D4 breakdown" EXACT [GOC:TermGenie] +synonym: "leukotriene D4 catabolism" EXACT [GOC:TermGenie] +synonym: "leukotriene D4 degradation" EXACT [GOC:TermGenie] +is_a: GO:0036100 ! leukotriene catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901748 ! leukotriene D4 metabolic process +created_by: yaf +creation_date: 2013-01-14T10:56:17Z + +[Term] +id: GO:1901750 +name: leukotriene D4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leukotriene D4." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00880] +synonym: "leukotriene D4 anabolism" EXACT [GOC:TermGenie] +synonym: "leukotriene D4 biosynthesis" EXACT [GOC:TermGenie] +synonym: "leukotriene D4 formation" EXACT [GOC:TermGenie] +synonym: "leukotriene D4 synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019370 ! leukotriene biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901748 ! leukotriene D4 metabolic process +created_by: yaf +creation_date: 2013-01-14T10:56:21Z + +[Term] +id: GO:1901751 +name: leukotriene A4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving leukotriene A4." [GOC:TermGenie, GOC:yaf] +synonym: "leukotriene A4 metabolism" EXACT [GOC:TermGenie] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0006691 ! leukotriene metabolic process +is_a: GO:0031407 ! oxylipin metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process +is_a: GO:0097176 ! epoxide metabolic process +created_by: yaf +creation_date: 2013-01-14T11:04:56Z + +[Term] +id: GO:1901752 +name: leukotriene A4 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of leukotriene A4." [GOC:TermGenie, GOC:yaf] +synonym: "leukotriene A4 breakdown" EXACT [GOC:TermGenie] +synonym: "leukotriene A4 catabolism" EXACT [GOC:TermGenie] +synonym: "leukotriene A4 degradation" EXACT [GOC:TermGenie] +is_a: GO:0036100 ! leukotriene catabolic process +is_a: GO:0042758 ! long-chain fatty acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901751 ! leukotriene A4 metabolic process +created_by: yaf +creation_date: 2013-01-14T11:05:04Z + +[Term] +id: GO:1901753 +name: leukotriene A4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of leukotriene A4." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00877] +synonym: "leukotriene A4 anabolism" EXACT [GOC:TermGenie] +synonym: "leukotriene A4 biosynthesis" EXACT [GOC:TermGenie] +synonym: "leukotriene A4 formation" EXACT [GOC:TermGenie] +synonym: "leukotriene A4 synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019370 ! leukotriene biosynthetic process +is_a: GO:0031408 ! oxylipin biosynthetic process +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901751 ! leukotriene A4 metabolic process +created_by: yaf +creation_date: 2013-01-14T11:05:09Z + +[Term] +id: GO:1901754 +name: vitamin D3 catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of vitamin D3." [GOC:TermGenie, GOC:yaf] +synonym: "calciol breakdown" EXACT [GOC:TermGenie] +synonym: "calciol catabolic process" EXACT [GOC:pr] +synonym: "calciol catabolism" EXACT [GOC:TermGenie] +synonym: "calciol degradation" EXACT [GOC:TermGenie] +synonym: "cholecalciferol catabolic process" EXACT [GOC:pr] +synonym: "cholecalciferol catabolism" EXACT [GOC:pr] +synonym: "vitamin D3 breakdown" EXACT [GOC:yaf] +synonym: "vitamin D3 catabolism" EXACT [GOC:yaf] +synonym: "vitamin D3 degradation" EXACT [GOC:yaf] +is_a: GO:0042369 ! vitamin D catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:0070640 ! vitamin D3 metabolic process +created_by: yaf +creation_date: 2013-01-14T11:11:04Z + +[Term] +id: GO:1901755 +name: vitamin D3 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of vitamin D3." [GOC:TermGenie, GOC:yaf, Unipathway:UPA00955] +synonym: "calciol anabolism" EXACT [GOC:TermGenie] +synonym: "calciol biosynthesis" EXACT [GOC:TermGenie] +synonym: "calciol biosynthetic process" EXACT [GOC:pr] +synonym: "calciol formation" EXACT [GOC:TermGenie] +synonym: "calciol synthesis" EXACT [GOC:TermGenie] +synonym: "cholecalciferol biosynthesis" EXACT [GOC:pr] +synonym: "cholecalciferol biosynthetic process" EXACT [GOC:pr] +synonym: "vitamin D3 anabolism" EXACT [GOC:yaf] +synonym: "vitamin D3 biosynthesis" EXACT [GOC:yaf] +synonym: "vitamin D3 formation" EXACT [GOC:yaf] +synonym: "vitamin D3 synthesis" EXACT [GOC:yaf] +is_a: GO:0042368 ! vitamin D biosynthetic process +is_a: GO:0070640 ! vitamin D3 metabolic process +is_a: GO:0120178 ! steroid hormone biosynthetic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process +created_by: yaf +creation_date: 2013-01-14T11:11:09Z + +[Term] +id: GO:1901756 +name: butirosin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving butirosin." [GOC:TermGenie, GOC:yaf] +synonym: "butirosin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016137 ! glycoside metabolic process +is_a: GO:0019751 ! polyol metabolic process +created_by: yaf +creation_date: 2013-01-14T11:36:18Z + +[Term] +id: GO:1901757 +name: butirosin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of butirosin." [GOC:TermGenie, GOC:yaf] +synonym: "butirosin breakdown" EXACT [GOC:TermGenie] +synonym: "butirosin catabolism" EXACT [GOC:TermGenie] +synonym: "butirosin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:1901756 ! butirosin metabolic process +created_by: yaf +creation_date: 2013-01-14T11:36:22Z + +[Term] +id: GO:1901758 +name: butirosin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of butirosin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00964] +synonym: "butirosin anabolism" EXACT [GOC:TermGenie] +synonym: "butirosin biosynthesis" EXACT [GOC:TermGenie] +synonym: "butirosin formation" EXACT [GOC:TermGenie] +synonym: "butirosin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:1901756 ! butirosin metabolic process +created_by: yaf +creation_date: 2013-01-14T11:36:27Z + +[Term] +id: GO:1901759 +name: beta-L-Ara4N-lipid A metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-L-Ara4N-lipid A." [GOC:TermGenie, GOC:yaf, PMID:17928292, PMID:19166326] +synonym: "4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process" EXACT [] +synonym: "4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism" EXACT [] +synonym: "beta-L-Ara4N-lipid A metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006664 ! glycolipid metabolic process +is_a: GO:1901269 ! lipooligosaccharide metabolic process +created_by: pr +creation_date: 2013-01-14T12:52:57Z + +[Term] +id: GO:1901760 +name: beta-L-Ara4N-lipid A biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system." [GOC:TermGenie, GOC:yaf, PMID:17928292, PMID:19166326, UniPathway:UPA00037] +synonym: "4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis" EXACT [] +synonym: "4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthetic process" EXACT [] +synonym: "beta-L-Ara4N-lipid A anabolism" EXACT [GOC:TermGenie] +synonym: "beta-L-Ara4N-lipid A biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-L-Ara4N-lipid A formation" EXACT [GOC:TermGenie] +synonym: "beta-L-Ara4N-lipid A synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0009247 ! glycolipid biosynthetic process +is_a: GO:1901271 ! lipooligosaccharide biosynthetic process +is_a: GO:1901759 ! beta-L-Ara4N-lipid A metabolic process +created_by: pr +creation_date: 2013-01-14T12:53:01Z + +[Term] +id: GO:1901761 +name: oxytetracycline metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving oxytetracycline." [GOC:TermGenie, GOC:yaf, PMID:8163168] +synonym: "oxytetracycline metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0030638 ! polyketide metabolic process +created_by: yaf +creation_date: 2013-01-15T09:52:50Z + +[Term] +id: GO:1901762 +name: oxytetracycline catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of oxytetracycline." [GOC:TermGenie, GOC:yaf, PMID:8163168] +synonym: "oxytetracycline breakdown" EXACT [GOC:TermGenie] +synonym: "oxytetracycline catabolism" EXACT [GOC:TermGenie] +synonym: "oxytetracycline degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901761 ! oxytetracycline metabolic process +created_by: yaf +creation_date: 2013-01-15T09:52:55Z + +[Term] +id: GO:1901763 +name: oxytetracycline biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of oxytetracycline." [GOC:TermGenie, GOC:yaf, PMID:8163168, UniPathway:UPA00926] +synonym: "oxytetracycline anabolism" EXACT [GOC:TermGenie] +synonym: "oxytetracycline biosynthesis" EXACT [GOC:TermGenie] +synonym: "oxytetracycline formation" EXACT [GOC:TermGenie] +synonym: "oxytetracycline synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:1901761 ! oxytetracycline metabolic process +created_by: yaf +creation_date: 2013-01-15T09:52:59Z + +[Term] +id: GO:1901764 +name: phosphinothricin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphinothricin." [GOC:TermGenie, GOC:yaf] +synonym: "phosphinothricin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0071704 ! organic substance metabolic process +created_by: yaf +creation_date: 2013-01-15T10:02:37Z + +[Term] +id: GO:1901765 +name: phosphinothricin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of phosphinothricin." [GOC:TermGenie, GOC:yaf] +synonym: "phosphinothricin breakdown" EXACT [GOC:TermGenie] +synonym: "phosphinothricin catabolism" EXACT [GOC:TermGenie] +synonym: "phosphinothricin degradation" EXACT [GOC:TermGenie] +is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:1901764 ! phosphinothricin metabolic process +created_by: yaf +creation_date: 2013-01-15T10:02:42Z + +[Term] +id: GO:1901766 +name: phosphinothricin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphinothricin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00168] +synonym: "phosphinothricin anabolism" EXACT [GOC:TermGenie] +synonym: "phosphinothricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "phosphinothricin formation" EXACT [GOC:TermGenie] +synonym: "phosphinothricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901576 ! organic substance biosynthetic process +is_a: GO:1901764 ! phosphinothricin metabolic process +created_by: yaf +creation_date: 2013-01-15T10:02:46Z + +[Term] +id: GO:1901767 +name: carbapenem metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving carbapenem." [GOC:TermGenie, GOC:yaf, PMID:9402024] +synonym: "carbapenem metabolism" EXACT [GOC:TermGenie] +is_a: GO:0030653 ! beta-lactam antibiotic metabolic process +created_by: yaf +creation_date: 2013-01-15T10:08:57Z + +[Term] +id: GO:1901768 +name: carbapenem catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of carbapenem." [GOC:TermGenie, GOC:yaf, PMID:9402024] +synonym: "carbapenem breakdown" EXACT [GOC:TermGenie] +synonym: "carbapenem catabolism" EXACT [GOC:TermGenie] +synonym: "carbapenem degradation" EXACT [GOC:TermGenie] +is_a: GO:0030655 ! beta-lactam antibiotic catabolic process +is_a: GO:1901767 ! carbapenem metabolic process +created_by: yaf +creation_date: 2013-01-15T10:09:02Z + +[Term] +id: GO:1901769 +name: carbapenem biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of carbapenem." [GOC:TermGenie, GOC:yaf, PMID:9402024, UniPathway:UPA00182] +synonym: "carbapenem anabolism" EXACT [GOC:TermGenie] +synonym: "carbapenem biosynthesis" EXACT [GOC:TermGenie] +synonym: "carbapenem formation" EXACT [GOC:TermGenie] +synonym: "carbapenem synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030654 ! beta-lactam antibiotic biosynthetic process +is_a: GO:1901767 ! carbapenem metabolic process +created_by: yaf +creation_date: 2013-01-15T10:09:06Z + +[Term] +id: GO:1901770 +name: daunorubicin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of daunorubicin." [GOC:TermGenie, GOC:yaf, PMID:7601857] +synonym: "daunorubicin breakdown" EXACT [GOC:TermGenie] +synonym: "daunorubicin catabolism" EXACT [GOC:TermGenie] +synonym: "daunorubicin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0030649 ! aminoglycoside antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0044597 ! daunorubicin metabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901662 ! quinone catabolic process +created_by: yaf +creation_date: 2013-01-15T10:14:29Z + +[Term] +id: GO:1901771 +name: daunorubicin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of daunorubicin." [GOC:TermGenie, GOC:yaf, PMID:7601857, UniPathway:UPA00054] +synonym: "daunorubicin anabolism" EXACT [GOC:TermGenie] +synonym: "daunorubicin biosynthesis" EXACT [GOC:TermGenie] +synonym: "daunorubicin formation" EXACT [GOC:TermGenie] +synonym: "daunorubicin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0030648 ! aminoglycoside antibiotic biosynthetic process +is_a: GO:0044597 ! daunorubicin metabolic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process +created_by: yaf +creation_date: 2013-01-15T10:14:33Z + +[Term] +id: GO:1901772 +name: lincomycin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lincomycin." [GOC:TermGenie, GOC:yaf, PMID:8577249] +synonym: "lincomycin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0016143 ! S-glycoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0043603 ! cellular amide metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: yaf +creation_date: 2013-01-15T11:53:52Z + +[Term] +id: GO:1901773 +name: lincomycin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lincomycin." [GOC:TermGenie, GOC:yaf, PMID:8577249] +synonym: "lincomycin breakdown" EXACT [GOC:TermGenie] +synonym: "lincomycin catabolism" EXACT [GOC:TermGenie] +synonym: "lincomycin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016145 ! S-glycoside catabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901772 ! lincomycin metabolic process +created_by: yaf +creation_date: 2013-01-15T11:53:57Z + +[Term] +id: GO:1901774 +name: lincomycin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lincomycin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6955, PMID:8577249, UniPathway:UPA00161] +synonym: "lincomycin anabolism" EXACT [GOC:TermGenie] +synonym: "lincomycin biosynthesis" EXACT [GOC:TermGenie] +synonym: "lincomycin formation" EXACT [GOC:TermGenie] +synonym: "lincomycin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016144 ! S-glycoside biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:0043604 ! amide biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901772 ! lincomycin metabolic process +created_by: yaf +creation_date: 2013-01-15T11:54:01Z + +[Term] +id: GO:1901775 +name: mitomycin C metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mitomycin C." [GOC:TermGenie, GOC:yaf, PMID:10094699, PMID:10099135] +synonym: "mitomycin C metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +is_a: GO:1901661 ! quinone metabolic process +created_by: yaf +creation_date: 2013-01-15T12:11:48Z + +[Term] +id: GO:1901776 +name: mitomycin C catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of mitomycin C." [GOC:TermGenie, GOC:yaf, PMID:10094699, PMID:10099135] +synonym: "mitomycin C breakdown" EXACT [GOC:TermGenie] +synonym: "mitomycin C catabolism" EXACT [GOC:TermGenie] +synonym: "mitomycin C degradation" EXACT [GOC:TermGenie] +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901662 ! quinone catabolic process +is_a: GO:1901775 ! mitomycin C metabolic process +created_by: yaf +creation_date: 2013-01-15T12:11:52Z + +[Term] +id: GO:1901777 +name: mitomycin C biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of mitomycin C." [GOC:TermGenie, GOC:yaf, PMID:10094699, PMID:10099135, UniPathway:UPA00851] +synonym: "mitomycin C anabolism" EXACT [GOC:TermGenie] +synonym: "mitomycin C biosynthesis" EXACT [GOC:TermGenie] +synonym: "mitomycin C formation" EXACT [GOC:TermGenie] +synonym: "mitomycin C synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901663 ! quinone biosynthetic process +is_a: GO:1901775 ! mitomycin C metabolic process +created_by: yaf +creation_date: 2013-01-15T12:11:57Z + +[Term] +id: GO:1901778 +name: pentalenolactone metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving pentalenolactone." [GOC:TermGenie, GOC:yaf, PMID:17178094] +synonym: "pentalenolactone metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0097176 ! epoxide metabolic process +is_a: GO:1901334 ! lactone metabolic process +created_by: yaf +creation_date: 2013-01-16T09:49:38Z + +[Term] +id: GO:1901779 +name: pentalenolactone catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pentalenolactone." [GOC:TermGenie, GOC:yaf, PMID:17178094] +synonym: "pentalenolactone breakdown" EXACT [GOC:TermGenie] +synonym: "pentalenolactone catabolism" EXACT [GOC:TermGenie] +synonym: "pentalenolactone degradation" EXACT [GOC:TermGenie] +is_a: GO:0016107 ! sesquiterpenoid catabolic process +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901335 ! lactone catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901778 ! pentalenolactone metabolic process +created_by: yaf +creation_date: 2013-01-16T09:49:42Z + +[Term] +id: GO:1901780 +name: pentalenolactone biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of pentalenolactone." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6915, PMID:17178094, UniPathway:UPA00974] +synonym: "pentalenolactone anabolism" EXACT [GOC:TermGenie] +synonym: "pentalenolactone biosynthesis" EXACT [GOC:TermGenie] +synonym: "pentalenolactone formation" EXACT [GOC:TermGenie] +synonym: "pentalenolactone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901336 ! lactone biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901778 ! pentalenolactone metabolic process +created_by: yaf +creation_date: 2013-01-16T09:49:47Z + +[Term] +id: GO:1901781 +name: p-cumate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving p-cumate." [GOC:TermGenie, GOC:yaf, PMID:8631713] +synonym: "p-cumate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: yaf +creation_date: 2013-01-16T10:40:28Z + +[Term] +id: GO:1901782 +name: p-cumate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of p-cumate." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5273, PMID:8631713, UniPathway:UPA00937] +synonym: "p-cumate breakdown" EXACT [GOC:TermGenie] +synonym: "p-cumate catabolism" EXACT [GOC:TermGenie] +synonym: "p-cumate degradation" EXACT [GOC:TermGenie] +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901781 ! p-cumate metabolic process +created_by: yaf +creation_date: 2013-01-16T10:40:32Z + +[Term] +id: GO:1901783 +name: p-cumate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of p-cumate." [GOC:TermGenie, GOC:yaf, PMID:8631713] +synonym: "p-cumate anabolism" EXACT [GOC:TermGenie] +synonym: "p-cumate biosynthesis" EXACT [GOC:TermGenie] +synonym: "p-cumate formation" EXACT [GOC:TermGenie] +synonym: "p-cumate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901781 ! p-cumate metabolic process +created_by: yaf +creation_date: 2013-01-16T10:40:36Z + +[Term] +id: GO:1901784 +name: p-cresol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving p-cresol." [GOC:TermGenie, GOC:yaf, PMID:10623531] +synonym: "p-cresol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0042212 ! cresol metabolic process +created_by: yaf +creation_date: 2013-01-16T11:03:59Z + +[Term] +id: GO:1901785 +name: p-cresol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of p-cresol." [GOC:TermGenie, GOC:yaf, PMID:10623531, UniPathway:UPA00708] +synonym: "p-cresol breakdown" EXACT [GOC:TermGenie] +synonym: "p-cresol catabolism" EXACT [GOC:TermGenie] +synonym: "p-cresol degradation" EXACT [GOC:TermGenie] +is_a: GO:0009407 ! toxin catabolic process +is_a: GO:0046199 ! cresol catabolic process +is_a: GO:1901784 ! p-cresol metabolic process +created_by: yaf +creation_date: 2013-01-16T11:04:04Z + +[Term] +id: GO:1901786 +name: p-cresol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of p-cresol." [GOC:TermGenie, GOC:yaf, PMID:10623531] +synonym: "p-cresol anabolism" EXACT [GOC:TermGenie] +synonym: "p-cresol biosynthesis" EXACT [GOC:TermGenie] +synonym: "p-cresol formation" EXACT [GOC:TermGenie] +synonym: "p-cresol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009403 ! toxin biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901784 ! p-cresol metabolic process +created_by: yaf +creation_date: 2013-01-16T11:04:08Z + +[Term] +id: GO:1901787 +name: benzoyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving benzoyl-CoA." [GOC:TermGenie, GOC:yaf] +synonym: "benzoyl-CoA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006637 ! acyl-CoA metabolic process +created_by: yaf +creation_date: 2013-01-16T11:13:54Z + +[Term] +id: GO:1901788 +name: benzoyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA." [GOC:TermGenie, GOC:yaf, MetaCyc:CENTBENZCOA-PWY, MetaCyc:P321-PWY, MetaCyc:PWY-1361, UniPathway:UPA00739] +synonym: "benzoyl-CoA breakdown" EXACT [GOC:TermGenie] +synonym: "benzoyl-CoA catabolism" EXACT [GOC:TermGenie] +synonym: "benzoyl-CoA degradation" EXACT [GOC:TermGenie] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901787 ! benzoyl-CoA metabolic process +created_by: yaf +creation_date: 2013-01-16T11:13:59Z + +[Term] +id: GO:1901789 +name: benzoyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of benzoyl-CoA." [GOC:TermGenie, GOC:yaf] +synonym: "benzoyl-CoA anabolism" EXACT [GOC:TermGenie] +synonym: "benzoyl-CoA biosynthesis" EXACT [GOC:TermGenie] +synonym: "benzoyl-CoA formation" EXACT [GOC:TermGenie] +synonym: "benzoyl-CoA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071616 ! acyl-CoA biosynthetic process +is_a: GO:1901787 ! benzoyl-CoA metabolic process +created_by: yaf +creation_date: 2013-01-16T11:14:03Z + +[Term] +id: GO:1901790 +name: 3-(2,3-dihydroxyphenyl)propanoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, MetaCyc:1.13.11.16-RXN, MetaCyc:HCAMHPDEG-PWY] +synonym: "3-(2,3-dihydroxyphenyl)propanoate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +created_by: yaf +creation_date: 2013-01-16T11:40:57Z + +[Term] +id: GO:1901791 +name: 3-(2,3-dihydroxyphenyl)propanoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, MetaCyc:1.13.11.16-RXN, MetaCyc:HCAMHPDEG-PWY, UniPathway:UPA00836] +synonym: "3-(2,3-dihydroxyphenyl)propanoate breakdown" EXACT [GOC:TermGenie] +synonym: "3-(2,3-dihydroxyphenyl)propanoate catabolism" EXACT [GOC:TermGenie] +synonym: "3-(2,3-dihydroxyphenyl)propanoate degradation" EXACT [GOC:TermGenie] +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901790 ! 3-(2,3-dihydroxyphenyl)propanoate metabolic process +created_by: yaf +creation_date: 2013-01-16T11:41:02Z + +[Term] +id: GO:1901792 +name: 3-(2,3-dihydroxyphenyl)propanoate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, MetaCyc:1.13.11.16-RXN, MetaCyc:HCAMHPDEG-PWY] +synonym: "3-(2,3-dihydroxyphenyl)propanoate anabolism" EXACT [GOC:TermGenie] +synonym: "3-(2,3-dihydroxyphenyl)propanoate biosynthesis" EXACT [GOC:TermGenie] +synonym: "3-(2,3-dihydroxyphenyl)propanoate formation" EXACT [GOC:TermGenie] +synonym: "3-(2,3-dihydroxyphenyl)propanoate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901790 ! 3-(2,3-dihydroxyphenyl)propanoate metabolic process +created_by: yaf +creation_date: 2013-01-16T11:41:06Z + +[Term] +id: GO:1901793 +name: 3-(3-hydroxyphenyl)propanoate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, PMID:10537203] +synonym: "3-(3-hydroxyphenyl)propanoate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +created_by: yaf +creation_date: 2013-01-16T11:47:09Z + +[Term] +id: GO:1901794 +name: 3-(3-hydroxyphenyl)propanoate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY0-1277, PMID:10537203, UniPathway:UPA00835] +synonym: "3-(3-hydroxyphenyl)propanoate breakdown" EXACT [GOC:TermGenie] +synonym: "3-(3-hydroxyphenyl)propanoate catabolism" EXACT [GOC:TermGenie] +synonym: "3-(3-hydroxyphenyl)propanoate degradation" EXACT [GOC:TermGenie] +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901793 ! 3-(3-hydroxyphenyl)propanoate metabolic process +created_by: yaf +creation_date: 2013-01-16T11:47:17Z + +[Term] +id: GO:1901795 +name: 3-(3-hydroxyphenyl)propanoate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, PMID:10537203] +synonym: "3-(3-hydroxyphenyl)propanoate anabolism" EXACT [GOC:TermGenie] +synonym: "3-(3-hydroxyphenyl)propanoate biosynthesis" EXACT [GOC:TermGenie] +synonym: "3-(3-hydroxyphenyl)propanoate formation" EXACT [GOC:TermGenie] +synonym: "3-(3-hydroxyphenyl)propanoate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901793 ! 3-(3-hydroxyphenyl)propanoate metabolic process +created_by: yaf +creation_date: 2013-01-16T11:47:21Z + +[Term] +id: GO:1901796 +name: regulation of signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator." [GOC:TermGenie] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072331 ! signal transduction by p53 class mediator +relationship: regulates GO:0072331 ! signal transduction by p53 class mediator +created_by: hjd +creation_date: 2013-01-18T21:51:39Z + +[Term] +id: GO:1901797 +name: negative regulation of signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator." [GOC:TermGenie] +synonym: "down regulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "inhibition of signal transduction by p53 class mediator" NARROW [GOC:TermGenie] +is_a: GO:1901796 ! regulation of signal transduction by p53 class mediator +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072331 ! signal transduction by p53 class mediator +relationship: negatively_regulates GO:0072331 ! signal transduction by p53 class mediator +created_by: hjd +creation_date: 2013-01-18T21:51:44Z + +[Term] +id: GO:1901798 +name: positive regulation of signal transduction by p53 class mediator +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator." [GOC:TermGenie] +synonym: "activation of signal transduction by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "up regulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +is_a: GO:1901796 ! regulation of signal transduction by p53 class mediator +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072331 ! signal transduction by p53 class mediator +relationship: positively_regulates GO:0072331 ! signal transduction by p53 class mediator +created_by: hjd +creation_date: 2013-01-18T21:51:48Z + +[Term] +id: GO:1901799 +name: negative regulation of proteasomal protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21669198] +synonym: "down regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of proteasomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +is_a: GO:0061136 ! regulation of proteasomal protein catabolic process +is_a: GO:1903051 ! negative regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010498 ! proteasomal protein catabolic process +relationship: negatively_regulates GO:0010498 ! proteasomal protein catabolic process +created_by: rl +creation_date: 2013-01-21T20:10:54Z + +[Term] +id: GO:1901800 +name: positive regulation of proteasomal protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21669198] +synonym: "activation of proteasomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasome-mediated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasome-mediated protein catabolism" EXACT [GOC:TermGenie] +is_a: GO:0061136 ! regulation of proteasomal protein catabolic process +is_a: GO:1903052 ! positive regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010498 ! proteasomal protein catabolic process +relationship: positively_regulates GO:0010498 ! proteasomal protein catabolic process +created_by: rl +creation_date: 2013-01-21T20:10:58Z + +[Term] +id: GO:1901801 +name: 1,5-anhydro-D-fructose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1,5-anhydro-D-fructose." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6992, PMID:15716041, UniPathway:UPA00738] +synonym: "1,5-anhydro-D-fructose metabolism" EXACT [GOC:TermGenie] +is_a: GO:0005996 ! monosaccharide metabolic process +is_a: GO:0019751 ! polyol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0097176 ! epoxide metabolic process +created_by: yaf +creation_date: 2013-01-22T09:56:20Z + +[Term] +id: GO:1901802 +name: 1,5-anhydro-D-fructose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6992, PMID:15716041, UniPathway:UPA00738] +synonym: "1,5-anhydro-D-fructose breakdown" EXACT [GOC:TermGenie] +synonym: "1,5-anhydro-D-fructose catabolism" EXACT [GOC:TermGenie] +synonym: "1,5-anhydro-D-fructose degradation" EXACT [GOC:TermGenie] +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046174 ! polyol catabolic process +is_a: GO:0046365 ! monosaccharide catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901801 ! 1,5-anhydro-D-fructose metabolic process +created_by: yaf +creation_date: 2013-01-22T09:56:25Z + +[Term] +id: GO:1901803 +name: 1,5-anhydro-D-fructose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6992, PMID:15716041, UniPathway:UPA00738] +synonym: "1,5-anhydro-D-fructose anabolism" EXACT [GOC:TermGenie] +synonym: "1,5-anhydro-D-fructose biosynthesis" EXACT [GOC:TermGenie] +synonym: "1,5-anhydro-D-fructose formation" EXACT [GOC:TermGenie] +synonym: "1,5-anhydro-D-fructose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046173 ! polyol biosynthetic process +is_a: GO:0046364 ! monosaccharide biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901801 ! 1,5-anhydro-D-fructose metabolic process +created_by: yaf +creation_date: 2013-01-22T09:56:34Z + +[Term] +id: GO:1901804 +name: beta-glucoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-glucoside." [GOC:TermGenie, GOC:yaf, PMID:15205427, PMID:16390337, PMID:8990303, Unipathway:UPA00237] +synonym: "beta-glucoside metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016137 ! glycoside metabolic process +created_by: yaf +creation_date: 2013-01-22T10:10:21Z + +[Term] +id: GO:1901805 +name: beta-glucoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-glucoside." [GOC:TermGenie, GOC:yaf, PMID:15205427, PMID:16390337, PMID:8990303, Unipathway:UPA00237] +synonym: "beta-glucoside breakdown" EXACT [GOC:TermGenie] +synonym: "beta-glucoside catabolism" EXACT [GOC:TermGenie] +synonym: "beta-glucoside degradation" EXACT [GOC:TermGenie] +is_a: GO:0016139 ! glycoside catabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: yaf +creation_date: 2013-01-22T10:10:26Z + +[Term] +id: GO:1901806 +name: beta-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-glucoside." [GOC:TermGenie, GOC:yaf, PMID:15205427, PMID:16390337, PMID:8990303, Unipathway:UPA00237] +synonym: "beta-glucoside anabolism" EXACT [GOC:TermGenie] +synonym: "beta-glucoside biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-glucoside formation" EXACT [GOC:TermGenie] +synonym: "beta-glucoside synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: yaf +creation_date: 2013-01-22T10:10:30Z + +[Term] +id: GO:1901807 +name: capsanthin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving capsanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, PMID:10995282, UniPathway:UPA00806] +synonym: "capsanthin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016122 ! xanthophyll metabolic process +created_by: yaf +creation_date: 2013-01-22T10:21:39Z + +[Term] +id: GO:1901808 +name: capsanthin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of capsanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, PMID:10995282, UniPathway:UPA00806] +synonym: "capsanthin breakdown" EXACT [GOC:TermGenie] +synonym: "capsanthin catabolism" EXACT [GOC:TermGenie] +synonym: "capsanthin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:1901807 ! capsanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T10:21:46Z + +[Term] +id: GO:1901809 +name: capsanthin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of capsanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, PMID:10995282, UniPathway:UPA00806] +synonym: "capsanthin anabolism" EXACT [GOC:TermGenie] +synonym: "capsanthin biosynthesis" EXACT [GOC:TermGenie] +synonym: "capsanthin formation" EXACT [GOC:TermGenie] +synonym: "capsanthin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:1901807 ! capsanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T10:21:50Z + +[Term] +id: GO:1901810 +name: beta-carotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5943, PMID:11387982, UniPathway:UPA00802] +synonym: "beta-carotene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:30:23Z + +[Term] +id: GO:1901811 +name: beta-carotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5943, PMID:11387982, UniPathway:UPA00802] +synonym: "beta-carotene breakdown" EXACT [GOC:TermGenie] +synonym: "beta-carotene catabolism" EXACT [GOC:TermGenie] +synonym: "beta-carotene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901810 ! beta-carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:30:28Z + +[Term] +id: GO:1901812 +name: beta-carotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5943, PMID:11387982, UniPathway:UPA00802] +synonym: "beta-carotene anabolism" EXACT [GOC:TermGenie] +synonym: "beta-carotene biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-carotene formation" EXACT [GOC:TermGenie] +synonym: "beta-carotene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901810 ! beta-carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:30:32Z + +[Term] +id: GO:1901813 +name: astaxanthin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving astaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5288, PMID:16434154, UniPathway:UPA00387] +synonym: "astaxanthin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016122 ! xanthophyll metabolic process +is_a: GO:0017144 ! drug metabolic process +created_by: yaf +creation_date: 2013-01-22T10:36:59Z + +[Term] +id: GO:1901814 +name: astaxanthin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of astaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5288, PMID:16434154, UniPathway:UPA00387] +synonym: "astaxanthin breakdown" EXACT [GOC:TermGenie] +synonym: "astaxanthin catabolism" EXACT [GOC:TermGenie] +synonym: "astaxanthin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:1901813 ! astaxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T10:37:03Z + +[Term] +id: GO:1901815 +name: astaxanthin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of astaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5288, PMID:16434154, UniPathway:UPA00387] +synonym: "astaxanthin anabolism" EXACT [GOC:TermGenie] +synonym: "astaxanthin biosynthesis" EXACT [GOC:TermGenie] +synonym: "astaxanthin formation" EXACT [GOC:TermGenie] +synonym: "astaxanthin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:1901813 ! astaxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T10:37:11Z + +[Term] +id: GO:1901816 +name: beta-zeacarotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:3710717, UniPathway:UPA00805] +synonym: "beta-zeacarotene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:42:03Z + +[Term] +id: GO:1901817 +name: beta-zeacarotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:3710717, UniPathway:UPA00805] +synonym: "beta-zeacarotene breakdown" EXACT [GOC:TermGenie] +synonym: "beta-zeacarotene catabolism" EXACT [GOC:TermGenie] +synonym: "beta-zeacarotene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901816 ! beta-zeacarotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:42:08Z + +[Term] +id: GO:1901818 +name: beta-zeacarotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:3710717, UniPathway:UPA00805] +synonym: "beta-zeacarotene anabolism" EXACT [GOC:TermGenie] +synonym: "beta-zeacarotene biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-zeacarotene formation" EXACT [GOC:TermGenie] +synonym: "beta-zeacarotene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901816 ! beta-zeacarotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:42:12Z + +[Term] +id: GO:1901819 +name: alpha-zeacarotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:6060456, UniPathway:UPA00804] +synonym: "alpha-zeacarotene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:51:02Z + +[Term] +id: GO:1901820 +name: alpha-zeacarotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:6060456, UniPathway:UPA00804] +synonym: "alpha-zeacarotene breakdown" EXACT [GOC:TermGenie] +synonym: "alpha-zeacarotene catabolism" EXACT [GOC:TermGenie] +synonym: "alpha-zeacarotene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901819 ! alpha-zeacarotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:51:06Z + +[Term] +id: GO:1901821 +name: alpha-zeacarotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alpha-zeacarotene." [GOC:TermGenie, GOC:yaf, PMID:6060456, UniPathway:UPA00804] +synonym: "alpha-zeacarotene anabolism" EXACT [GOC:TermGenie] +synonym: "alpha-zeacarotene biosynthesis" EXACT [GOC:TermGenie] +synonym: "alpha-zeacarotene formation" EXACT [GOC:TermGenie] +synonym: "alpha-zeacarotene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901819 ! alpha-zeacarotene metabolic process +created_by: yaf +creation_date: 2013-01-22T10:51:14Z + +[Term] +id: GO:1901822 +name: delta-carotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving delta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5946, PMID:8837512, UniPathway:UPA00801] +synonym: "delta-carotene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:0016119 ! carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T11:17:29Z + +[Term] +id: GO:1901823 +name: delta-carotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of delta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5946, PMID:8837512, UniPathway:UPA00801] +synonym: "delta-carotene breakdown" EXACT [GOC:TermGenie] +synonym: "delta-carotene catabolism" EXACT [GOC:TermGenie] +synonym: "delta-carotene degradation" EXACT [GOC:TermGenie] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:0016121 ! carotene catabolic process +is_a: GO:1901822 ! delta-carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T11:17:34Z + +[Term] +id: GO:1901824 +name: delta-carotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of delta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5946, PMID:8837512, UniPathway:UPA00801] +synonym: "delta-carotene anabolism" EXACT [GOC:TermGenie] +synonym: "delta-carotene biosynthesis" EXACT [GOC:TermGenie] +synonym: "delta-carotene formation" EXACT [GOC:TermGenie] +synonym: "delta-carotene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:0016120 ! carotene biosynthetic process +is_a: GO:1901822 ! delta-carotene metabolic process +created_by: yaf +creation_date: 2013-01-22T11:17:38Z + +[Term] +id: GO:1901825 +name: zeaxanthin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving zeaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5944, UniPathway:UPA00843] +synonym: "zeaxanthin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016122 ! xanthophyll metabolic process +created_by: yaf +creation_date: 2013-01-22T11:36:55Z + +[Term] +id: GO:1901826 +name: zeaxanthin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of zeaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5944, UniPathway:UPA00843] +synonym: "zeaxanthin breakdown" EXACT [GOC:TermGenie] +synonym: "zeaxanthin catabolism" EXACT [GOC:TermGenie] +synonym: "zeaxanthin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:1901825 ! zeaxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T11:37:00Z + +[Term] +id: GO:1901827 +name: zeaxanthin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of zeaxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5944, UniPathway:UPA00843] +synonym: "zeaxanthin anabolism" EXACT [GOC:TermGenie] +synonym: "zeaxanthin biosynthesis" EXACT [GOC:TermGenie] +synonym: "zeaxanthin formation" EXACT [GOC:TermGenie] +synonym: "zeaxanthin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:1901825 ! zeaxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T11:37:07Z + +[Term] +id: GO:1901828 +name: zeaxanthin bis(beta-D-glucoside) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside)." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6288, PMID:20075616, UniPathway:UPA00798] +synonym: "zeaxanthin bis(beta-D-glucoside) metabolism" EXACT [GOC:TermGenie] +synonym: "zeaxanthin diglucoside metabolism" EXACT [GOC:yaf] +is_a: GO:0016116 ! carotenoid metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: yaf +creation_date: 2013-01-22T12:31:56Z + +[Term] +id: GO:1901829 +name: zeaxanthin bis(beta-D-glucoside) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside)." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6288, PMID:20075616, UniPathway:UPA00798] +synonym: "zeaxanthin bis(beta-D-glucoside) breakdown" EXACT [GOC:TermGenie] +synonym: "zeaxanthin bis(beta-D-glucoside) catabolism" EXACT [GOC:TermGenie] +synonym: "zeaxanthin bis(beta-D-glucoside) degradation" EXACT [GOC:TermGenie] +synonym: "zeaxanthin diglucoside breakdown" EXACT [GOC:yaf] +synonym: "zeaxanthin diglucoside catabolism" EXACT [GOC:yaf] +synonym: "zeaxanthin diglucoside degradation" EXACT [GOC:yaf] +is_a: GO:0016118 ! carotenoid catabolic process +is_a: GO:1901805 ! beta-glucoside catabolic process +is_a: GO:1901828 ! zeaxanthin bis(beta-D-glucoside) metabolic process +created_by: yaf +creation_date: 2013-01-22T12:32:06Z + +[Term] +id: GO:1901830 +name: zeaxanthin bis(beta-D-glucoside) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside)." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6288, PMID:20075616, UniPathway:UPA00798] +synonym: "zeaxanthin bis(beta-D-glucoside) anabolism" EXACT [GOC:TermGenie] +synonym: "zeaxanthin bis(beta-D-glucoside) biosynthesis" EXACT [GOC:TermGenie] +synonym: "zeaxanthin bis(beta-D-glucoside) formation" EXACT [GOC:TermGenie] +synonym: "zeaxanthin bis(beta-D-glucoside) synthesis" EXACT [GOC:TermGenie] +synonym: "zeaxanthin diglucoside anabolism" EXACT [GOC:yaf] +synonym: "zeaxanthin diglucoside biosynthesis" EXACT [GOC:yaf] +synonym: "zeaxanthin diglucoside formation" EXACT [GOC:yaf] +synonym: "zeaxanthin diglucoside synthesis" EXACT [GOC:yaf] +is_a: GO:0016117 ! carotenoid biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process +is_a: GO:1901828 ! zeaxanthin bis(beta-D-glucoside) metabolic process +created_by: yaf +creation_date: 2013-01-22T12:32:10Z + +[Term] +id: GO:1901831 +name: all-trans-neoxanthin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving all-trans-neoxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6809, PMID:11029576, UniPathway:UPA00388] +synonym: "all-trans-neoxanthin metabolism" EXACT [GOC:TermGenie] +synonym: "neoxanthin metabolic process" EXACT [GOC:yaf] +synonym: "neoxanthin metabolism" EXACT [GOC:yaf] +is_a: GO:0016122 ! xanthophyll metabolic process +is_a: GO:0097176 ! epoxide metabolic process +created_by: yaf +creation_date: 2013-01-22T12:43:46Z + +[Term] +id: GO:1901832 +name: all-trans-neoxanthin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6809, PMID:11029576, UniPathway:UPA00388] +synonym: "all-trans-neoxanthin breakdown" EXACT [GOC:TermGenie] +synonym: "all-trans-neoxanthin catabolism" EXACT [GOC:TermGenie] +synonym: "all-trans-neoxanthin degradation" EXACT [GOC:TermGenie] +synonym: "neoxanthin breakdown" EXACT [GOC:yaf] +synonym: "neoxanthin catabolic process" EXACT [GOC:yaf] +synonym: "neoxanthin catabolism" EXACT [GOC:yaf] +synonym: "neoxanthin degradation" EXACT [GOC:yaf] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901831 ! all-trans-neoxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T12:43:51Z + +[Term] +id: GO:1901833 +name: all-trans-neoxanthin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6809, PMID:11029576, UniPathway:UPA00388] +synonym: "all-trans-neoxanthin anabolism" EXACT [GOC:TermGenie] +synonym: "all-trans-neoxanthin biosynthesis" EXACT [GOC:TermGenie] +synonym: "all-trans-neoxanthin formation" EXACT [GOC:TermGenie] +synonym: "all-trans-neoxanthin synthesis" EXACT [GOC:TermGenie] +synonym: "neoxanthin anabolism" EXACT [GOC:yaf] +synonym: "neoxanthin biosynthesis" EXACT [GOC:yaf] +synonym: "neoxanthin biosynthetic process" EXACT [GOC:yaf] +synonym: "neoxanthin formation" EXACT [GOC:yaf] +synonym: "neoxanthin synthesis" EXACT [GOC:yaf] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1901831 ! all-trans-neoxanthin metabolic process +created_by: yaf +creation_date: 2013-01-22T12:43:56Z + +[Term] +id: GO:1901834 +name: regulation of deadenylation-independent decapping of nuclear-transcribed mRNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA." [GOC:TermGenie] +synonym: "regulation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "regulation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +is_a: GO:0061013 ! regulation of mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031087 ! deadenylation-independent decapping of nuclear-transcribed mRNA +relationship: regulates GO:0031087 ! deadenylation-independent decapping of nuclear-transcribed mRNA +created_by: al +creation_date: 2013-01-22T22:42:17Z + +[Term] +id: GO:1901835 +name: positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA." [GOC:TermGenie] +synonym: "activation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "activation of deadenylation-independent decapping of nuclear-transcribed mRNA" NARROW [GOC:TermGenie] +synonym: "activation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +synonym: "positive regulation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "positive regulation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +synonym: "up regulation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "up regulation of deadenylation-independent decapping of nuclear-transcribed mRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +synonym: "up-regulation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "up-regulation of deadenylation-independent decapping of nuclear-transcribed mRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +synonym: "upregulation of deadenylation-independent decapping of nuclear mRNA" RELATED [GOC:TermGenie] +synonym: "upregulation of deadenylation-independent decapping of nuclear-transcribed mRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of deadenylylation-independent decapping" EXACT [GOC:TermGenie] +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +is_a: GO:1901834 ! regulation of deadenylation-independent decapping of nuclear-transcribed mRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031087 ! deadenylation-independent decapping of nuclear-transcribed mRNA +relationship: positively_regulates GO:0031087 ! deadenylation-independent decapping of nuclear-transcribed mRNA +created_by: al +creation_date: 2013-01-22T22:42:22Z + +[Term] +id: GO:1901836 +name: regulation of transcription of nucleolar large rRNA by RNA polymerase I +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I." [GOC:sart, GOC:TermGenie] +synonym: "regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [] +synonym: "regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +relationship: regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +created_by: sart +creation_date: 2013-01-23T10:16:27Z + +[Term] +id: GO:1901837 +name: negative regulation of transcription of nucleolar large rRNA by RNA polymerase I +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I." [GOC:sart, GOC:TermGenie] +synonym: "down regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [] +synonym: "negative regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +is_a: GO:0016479 ! negative regulation of transcription by RNA polymerase I +is_a: GO:1901836 ! regulation of transcription of nucleolar large rRNA by RNA polymerase I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +relationship: negatively_regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +created_by: sart +creation_date: 2013-01-23T10:16:31Z + +[Term] +id: GO:1901838 +name: positive regulation of transcription of nucleolar large rRNA by RNA polymerase I +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I." [GOC:sart, GOC:TermGenie] +synonym: "activation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" NARROW [GOC:TermGenie] +synonym: "activation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [] +synonym: "positive regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription of nuclear rRNA large Pol I transcript" EXACT [GOC:TermGenie] +is_a: GO:0045943 ! positive regulation of transcription by RNA polymerase I +is_a: GO:1901836 ! regulation of transcription of nucleolar large rRNA by RNA polymerase I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +relationship: positively_regulates GO:0042790 ! nucleolar large rRNA transcription by RNA polymerase I +created_by: sart +creation_date: 2013-01-23T10:16:36Z + +[Term] +id: GO:1901839 +name: regulation of RNA polymerase I regulatory region sequence-specific DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding." [GOC:sart, GOC:TermGenie] +is_a: GO:2000677 ! regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +relationship: regulates GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +created_by: sart +creation_date: 2013-01-23T10:24:33Z + +[Term] +id: GO:1901840 +name: negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding." [GOC:sart, GOC:TermGenie] +synonym: "down regulation of RNA polymerase I regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA polymerase I regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA polymerase I regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA polymerase I regulatory region sequence-specific DNA binding" NARROW [GOC:TermGenie] +is_a: GO:1901839 ! regulation of RNA polymerase I regulatory region sequence-specific DNA binding +is_a: GO:2000678 ! negative regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +relationship: negatively_regulates GO:0001163 ! RNA polymerase I transcription regulatory region sequence-specific DNA binding +created_by: sart +creation_date: 2013-01-23T10:24:37Z + +[Term] +id: GO:1901841 +name: regulation of high voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] +synonym: "regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008331 ! high voltage-gated calcium channel activity +relationship: regulates GO:0008331 ! high voltage-gated calcium channel activity +created_by: rl +creation_date: 2013-01-24T19:02:15Z + +[Term] +id: GO:1901842 +name: negative regulation of high voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] +synonym: "down regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of high voltage-gated calcium channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901386 ! negative regulation of voltage-gated calcium channel activity +is_a: GO:1901841 ! regulation of high voltage-gated calcium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008331 ! high voltage-gated calcium channel activity +relationship: negatively_regulates GO:0008331 ! high voltage-gated calcium channel activity +created_by: rl +creation_date: 2013-01-24T19:02:20Z + +[Term] +id: GO:1901843 +name: positive regulation of high voltage-gated calcium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] +synonym: "activation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "activation of high voltage-gated calcium channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901387 ! positive regulation of voltage-gated calcium channel activity +is_a: GO:1901841 ! regulation of high voltage-gated calcium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008331 ! high voltage-gated calcium channel activity +relationship: positively_regulates GO:0008331 ! high voltage-gated calcium channel activity +created_by: rl +creation_date: 2013-01-24T19:02:25Z + +[Term] +id: GO:1901844 +name: regulation of cell communication by electrical coupling involved in cardiac conduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17130302] +is_a: GO:0010649 ! regulation of cell communication by electrical coupling +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +relationship: regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +created_by: rl +creation_date: 2013-01-24T19:15:39Z + +[Term] +id: GO:1901845 +name: negative regulation of cell communication by electrical coupling involved in cardiac conduction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17130302] +synonym: "down regulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +synonym: "downregulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +synonym: "inhibition of cell communication by electrical coupling involved in cardiac conduction" NARROW [GOC:TermGenie] +is_a: GO:0010651 ! negative regulation of cell communication by electrical coupling +is_a: GO:1901844 ! regulation of cell communication by electrical coupling involved in cardiac conduction +is_a: GO:1903780 ! negative regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +relationship: negatively_regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +created_by: rl +creation_date: 2013-01-24T19:15:44Z + +[Term] +id: GO:1901846 +name: positive regulation of cell communication by electrical coupling involved in cardiac conduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17130302] +synonym: "activation of cell communication by electrical coupling involved in cardiac conduction" NARROW [GOC:TermGenie] +synonym: "up regulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +synonym: "upregulation of cell communication by electrical coupling involved in cardiac conduction" EXACT [GOC:TermGenie] +is_a: GO:0010650 ! positive regulation of cell communication by electrical coupling +is_a: GO:1901844 ! regulation of cell communication by electrical coupling involved in cardiac conduction +is_a: GO:1903781 ! positive regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +relationship: positively_regulates GO:0086064 ! cell communication by electrical coupling involved in cardiac conduction +created_by: rl +creation_date: 2013-01-24T19:15:49Z + +[Term] +id: GO:1901847 +name: nicotinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving nicotinate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00830] +synonym: "nicotinate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0006767 ! water-soluble vitamin metabolic process +is_a: GO:0009820 ! alkaloid metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +created_by: yaf +creation_date: 2013-01-28T11:23:48Z + +[Term] +id: GO:1901848 +name: nicotinate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of nicotinate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00830] +synonym: "nicotinate breakdown" EXACT [GOC:TermGenie] +synonym: "nicotinate catabolism" EXACT [GOC:TermGenie] +synonym: "nicotinate degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0042365 ! water-soluble vitamin catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:0072526 ! pyridine-containing compound catabolic process +is_a: GO:1901847 ! nicotinate metabolic process +created_by: yaf +creation_date: 2013-01-28T11:23:52Z + +[Term] +id: GO:1901849 +name: nicotinate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of nicotinate." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00830] +synonym: "nicotinate anabolism" EXACT [GOC:TermGenie] +synonym: "nicotinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "nicotinate formation" EXACT [GOC:TermGenie] +synonym: "nicotinate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009821 ! alkaloid biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0042364 ! water-soluble vitamin biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process +is_a: GO:1901847 ! nicotinate metabolic process +created_by: yaf +creation_date: 2013-01-28T11:23:57Z + +[Term] +id: GO:1901850 +name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin." [GOC:TermGenie, GOC:yaf, PMID:14593448, UniPathway:UPA00072] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolism" EXACT [GOC:TermGenie] +synonym: "coenzyme F0 metabolism" EXACT [GOC:yaf] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:0051186 ! cofactor metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +is_a: GO:1901564 ! organonitrogen compound metabolic process +created_by: yaf +creation_date: 2013-01-28T11:38:32Z + +[Term] +id: GO:1901851 +name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin." [GOC:TermGenie, GOC:yaf, PMID:14593448, UniPathway:UPA00072] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown" EXACT [GOC:TermGenie] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism" EXACT [GOC:TermGenie] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation" EXACT [GOC:TermGenie] +synonym: "coenzyme F0 breakdown" EXACT [GOC:yaf] +synonym: "coenzyme F0 catabolic process" EXACT [GOC:yaf] +synonym: "coenzyme F0 catabolism" EXACT [GOC:yaf] +synonym: "coenzyme F0 degradation" EXACT [GOC:yaf] +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0051187 ! cofactor catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901565 ! organonitrogen compound catabolic process +is_a: GO:1901850 ! 7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process +created_by: yaf +creation_date: 2013-01-28T11:38:36Z + +[Term] +id: GO:1901852 +name: 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin." [GOC:TermGenie, GOC:yaf, PMID:14593448, UniPathway:UPA00072] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin anabolism" EXACT [GOC:TermGenie] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis" EXACT [GOC:TermGenie] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin formation" EXACT [GOC:TermGenie] +synonym: "7,8-didemethyl-8-hydroxy-5-deazariboflavin synthesis" EXACT [GOC:TermGenie] +synonym: "coenzyme F0 anabolism" EXACT [GOC:yaf] +synonym: "coenzyme F0 biosynthesis" EXACT [GOC:yaf] +synonym: "coenzyme F0 biosynthetic process" EXACT [GOC:yaf] +synonym: "coenzyme F0 formation" EXACT [GOC:yaf] +synonym: "coenzyme F0 synthesis" EXACT [GOC:yaf] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0051188 ! cofactor biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1901850 ! 7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process +created_by: yaf +creation_date: 2013-01-28T11:38:41Z + +[Term] +id: GO:1901853 +name: 5,6,7,8-tetrahydrosarcinapterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00069] +synonym: "5,6,7,8-tetrahydrosarcinapterin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0072350 ! tricarboxylic acid metabolic process +is_a: GO:2001117 ! tetrahydromethanopterin metabolic process +created_by: yaf +creation_date: 2013-01-28T11:47:52Z + +[Term] +id: GO:1901854 +name: 5,6,7,8-tetrahydrosarcinapterin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00069] +synonym: "5,6,7,8-tetrahydrosarcinapterin breakdown" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydrosarcinapterin catabolism" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydrosarcinapterin degradation" EXACT [GOC:TermGenie] +is_a: GO:0042560 ! pteridine-containing compound catabolic process +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:0072352 ! tricarboxylic acid catabolic process +is_a: GO:1901853 ! 5,6,7,8-tetrahydrosarcinapterin metabolic process +created_by: yaf +creation_date: 2013-01-28T11:48:01Z + +[Term] +id: GO:1901855 +name: 5,6,7,8-tetrahydrosarcinapterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00069] +synonym: "5,6,7,8-tetrahydrosarcinapterin anabolism" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydrosarcinapterin biosynthesis" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydrosarcinapterin formation" EXACT [GOC:TermGenie] +synonym: "5,6,7,8-tetrahydrosarcinapterin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process +is_a: GO:1901853 ! 5,6,7,8-tetrahydrosarcinapterin metabolic process +is_a: GO:2001118 ! tetrahydromethanopterin biosynthetic process +created_by: yaf +creation_date: 2013-01-28T11:48:05Z + +[Term] +id: GO:1901856 +name: negative regulation of cellular respiration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "down regulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of respiration" BROAD [GOC:TermGenie] +synonym: "down-regulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of respiration" BROAD [GOC:TermGenie] +synonym: "downregulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of respiration" BROAD [GOC:TermGenie] +synonym: "inhibition of cellular respiration" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of respiration" BROAD [GOC:TermGenie] +synonym: "negative regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of respiration" BROAD [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045333 ! cellular respiration +relationship: negatively_regulates GO:0045333 ! cellular respiration +created_by: yaf +creation_date: 2013-02-01T09:56:23Z + +[Term] +id: GO:1901857 +name: positive regulation of cellular respiration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular respiration." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "activation of cellular respiration" NARROW [GOC:TermGenie] +synonym: "activation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "activation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "activation of respiration" BROAD [GOC:TermGenie] +synonym: "positive regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of respiration" BROAD [GOC:TermGenie] +synonym: "up regulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of respiration" BROAD [GOC:TermGenie] +synonym: "up-regulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of respiration" BROAD [GOC:TermGenie] +synonym: "upregulation of cellular respiration" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidative metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidative metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of respiration" BROAD [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0043457 ! regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045333 ! cellular respiration +relationship: positively_regulates GO:0045333 ! cellular respiration +created_by: yaf +creation_date: 2013-02-01T09:56:28Z + +[Term] +id: GO:1901858 +name: regulation of mitochondrial DNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032042 ! mitochondrial DNA metabolic process +relationship: regulates GO:0032042 ! mitochondrial DNA metabolic process +created_by: yaf +creation_date: 2013-02-01T10:05:04Z + +[Term] +id: GO:1901859 +name: negative regulation of mitochondrial DNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "down regulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial DNA metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:1901858 ! regulation of mitochondrial DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032042 ! mitochondrial DNA metabolic process +relationship: negatively_regulates GO:0032042 ! mitochondrial DNA metabolic process +created_by: yaf +creation_date: 2013-02-01T10:05:09Z + +[Term] +id: GO:1901860 +name: positive regulation of mitochondrial DNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "activation of mitochondrial DNA metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "activation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "activation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mtDNA metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial DNA metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial DNA metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mtDNA metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mtDNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:1901858 ! regulation of mitochondrial DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032042 ! mitochondrial DNA metabolic process +relationship: positively_regulates GO:0032042 ! mitochondrial DNA metabolic process +created_by: yaf +creation_date: 2013-02-01T10:05:14Z + +[Term] +id: GO:1901861 +name: regulation of muscle tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060537 ! muscle tissue development +relationship: regulates GO:0060537 ! muscle tissue development +created_by: yaf +creation_date: 2013-02-01T10:30:47Z + +[Term] +id: GO:1901862 +name: negative regulation of muscle tissue development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie] +synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie] +synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie] +synonym: "inhibition of muscle tissue development" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1901861 ! regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060537 ! muscle tissue development +relationship: negatively_regulates GO:0060537 ! muscle tissue development +created_by: yaf +creation_date: 2013-02-01T10:30:52Z + +[Term] +id: GO:1901863 +name: positive regulation of muscle tissue development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] +synonym: "activation of muscle tissue development" NARROW [GOC:TermGenie] +synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie] +synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie] +synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1901861 ! regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060537 ! muscle tissue development +relationship: positively_regulates GO:0060537 ! muscle tissue development +created_by: yaf +creation_date: 2013-02-01T10:30:57Z + +[Term] +id: GO:1901864 +name: capsorubin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving capsorubin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, UniPathway:UPA00807] +synonym: "capsorubin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016122 ! xanthophyll metabolic process +created_by: yaf +creation_date: 2013-02-04T10:50:13Z + +[Term] +id: GO:1901865 +name: capsorubin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of capsorubin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, UniPathway:UPA00807] +synonym: "capsorubin breakdown" EXACT [GOC:TermGenie] +synonym: "capsorubin catabolism" EXACT [GOC:TermGenie] +synonym: "capsorubin degradation" EXACT [GOC:TermGenie] +is_a: GO:0016124 ! xanthophyll catabolic process +is_a: GO:1901864 ! capsorubin metabolic process +created_by: yaf +creation_date: 2013-02-04T10:50:17Z + +[Term] +id: GO:1901866 +name: capsorubin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of capsorubin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, UniPathway:UPA00807] +synonym: "capsorubin anabolism" EXACT [GOC:TermGenie] +synonym: "capsorubin biosynthesis" EXACT [GOC:TermGenie] +synonym: "capsorubin formation" EXACT [GOC:TermGenie] +synonym: "capsorubin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016123 ! xanthophyll biosynthetic process +is_a: GO:1901864 ! capsorubin metabolic process +created_by: yaf +creation_date: 2013-02-04T10:50:26Z + +[Term] +id: GO:1901867 +name: ecgonine methyl ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ecgonine methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonine methyl ester metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0046448 ! tropane alkaloid metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:14Z + +[Term] +id: GO:1901868 +name: ecgonine methyl ester catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonine methyl ester breakdown" EXACT [GOC:TermGenie] +synonym: "ecgonine methyl ester catabolism" EXACT [GOC:TermGenie] +synonym: "ecgonine methyl ester degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901867 ! ecgonine methyl ester metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:18Z + +[Term] +id: GO:1901869 +name: ecgonine methyl ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ecgonine methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonine methyl ester anabolism" EXACT [GOC:TermGenie] +synonym: "ecgonine methyl ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "ecgonine methyl ester formation" EXACT [GOC:TermGenie] +synonym: "ecgonine methyl ester synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009710 ! tropane alkaloid biosynthetic process +is_a: GO:1901867 ! ecgonine methyl ester metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:25Z + +[Term] +id: GO:1901870 +name: ecgonone methyl ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ecgonone methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonone methyl ester metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046448 ! tropane alkaloid metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:30Z + +[Term] +id: GO:1901871 +name: ecgonone methyl ester catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonone methyl ester breakdown" EXACT [GOC:TermGenie] +synonym: "ecgonone methyl ester catabolism" EXACT [GOC:TermGenie] +synonym: "ecgonone methyl ester degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901870 ! ecgonone methyl ester metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:34Z + +[Term] +id: GO:1901872 +name: ecgonone methyl ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ecgonone methyl ester." [GOC:TermGenie, PMID:22665766] +synonym: "ecgonone methyl ester anabolism" EXACT [GOC:TermGenie] +synonym: "ecgonone methyl ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "ecgonone methyl ester formation" EXACT [GOC:TermGenie] +synonym: "ecgonone methyl ester synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009710 ! tropane alkaloid biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1901870 ! ecgonone methyl ester metabolic process +created_by: ms +creation_date: 2013-02-04T11:58:39Z + +[Term] +id: GO:1901873 +name: regulation of post-translational protein modification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of post-translational protein modification." [GOC:TermGenie, GOC:yaf, PMID:21209915] +synonym: "regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "regulation of PTM" EXACT [GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043687 ! post-translational protein modification +relationship: regulates GO:0043687 ! post-translational protein modification +created_by: yaf +creation_date: 2013-02-05T10:02:52Z + +[Term] +id: GO:1901874 +name: negative regulation of post-translational protein modification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification." [GOC:TermGenie, GOC:yaf, PMID:21209915] +synonym: "down regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "down regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "down regulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "down regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "down regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "down regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "down regulation of PTM" EXACT [GOC:TermGenie] +synonym: "down-regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of PTM" EXACT [GOC:TermGenie] +synonym: "downregulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "downregulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "downregulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "downregulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "downregulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "downregulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "downregulation of PTM" EXACT [GOC:TermGenie] +synonym: "inhibition of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "inhibition of post-translational modification" EXACT [GOC:TermGenie] +synonym: "inhibition of post-translational protein modification" NARROW [GOC:TermGenie] +synonym: "inhibition of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "inhibition of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "inhibition of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "inhibition of PTM" EXACT [GOC:TermGenie] +synonym: "negative regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of PTM" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1901873 ! regulation of post-translational protein modification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043687 ! post-translational protein modification +relationship: negatively_regulates GO:0043687 ! post-translational protein modification +created_by: yaf +creation_date: 2013-02-05T10:02:57Z + +[Term] +id: GO:1901875 +name: positive regulation of post-translational protein modification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of post-translational protein modification." [GOC:TermGenie, GOC:yaf, PMID:21209915] +synonym: "activation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "activation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "activation of post-translational protein modification" NARROW [GOC:TermGenie] +synonym: "activation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "activation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "activation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "activation of PTM" EXACT [GOC:TermGenie] +synonym: "positive regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of PTM" EXACT [GOC:TermGenie] +synonym: "up regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "up regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "up regulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "up regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "up regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "up regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "up regulation of PTM" EXACT [GOC:TermGenie] +synonym: "up-regulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of PTM" EXACT [GOC:TermGenie] +synonym: "upregulation of post-translational amino acid modification" EXACT [GOC:TermGenie] +synonym: "upregulation of post-translational modification" EXACT [GOC:TermGenie] +synonym: "upregulation of post-translational protein modification" EXACT [GOC:TermGenie] +synonym: "upregulation of posttranslational amino acid modification" EXACT [GOC:TermGenie] +synonym: "upregulation of posttranslational modification" EXACT [GOC:TermGenie] +synonym: "upregulation of posttranslational protein modification" EXACT [GOC:TermGenie] +synonym: "upregulation of PTM" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1901873 ! regulation of post-translational protein modification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043687 ! post-translational protein modification +relationship: positively_regulates GO:0043687 ! post-translational protein modification +created_by: yaf +creation_date: 2013-02-05T10:03:02Z + +[Term] +id: GO:1901876 +name: regulation of calcium ion binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion binding." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16432188] +synonym: "regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005509 ! calcium ion binding +relationship: regulates GO:0005509 ! calcium ion binding +created_by: rl +creation_date: 2013-02-06T12:38:12Z + +[Term] +id: GO:1901877 +name: negative regulation of calcium ion binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16432188] +synonym: "down regulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "down regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "downregulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "inhibition of calcium ion binding" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1901876 ! regulation of calcium ion binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005509 ! calcium ion binding +relationship: negatively_regulates GO:0005509 ! calcium ion binding +created_by: rl +creation_date: 2013-02-06T12:38:22Z + +[Term] +id: GO:1901878 +name: positive regulation of calcium ion binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion binding." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16432188] +synonym: "activation of calcium ion binding" NARROW [GOC:TermGenie] +synonym: "activation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "up regulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion storage activity" RELATED [GOC:TermGenie] +synonym: "upregulation of calcium ion binding" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion storage activity" RELATED [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1901876 ! regulation of calcium ion binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005509 ! calcium ion binding +relationship: positively_regulates GO:0005509 ! calcium ion binding +created_by: rl +creation_date: 2013-02-06T12:38:26Z + +[Term] +id: GO:1901879 +name: regulation of protein depolymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] +synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie] +is_a: GO:0043244 ! regulation of protein-containing complex disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051261 ! protein depolymerization +relationship: regulates GO:0051261 ! protein depolymerization +created_by: rl +creation_date: 2013-02-06T13:57:23Z + +[Term] +id: GO:1901880 +name: negative regulation of protein depolymerization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] +synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein depolymerization" NARROW [GOC:TermGenie] +synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie] +is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051261 ! protein depolymerization +relationship: negatively_regulates GO:0051261 ! protein depolymerization +created_by: rl +creation_date: 2013-02-06T13:57:28Z + +[Term] +id: GO:1901881 +name: positive regulation of protein depolymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] +synonym: "activation of protein depolymerization" NARROW [GOC:TermGenie] +synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie] +is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051261 ! protein depolymerization +relationship: positively_regulates GO:0051261 ! protein depolymerization +created_by: rl +creation_date: 2013-02-06T13:57:32Z + +[Term] +id: GO:1901882 +name: 4-hydroxycoumarin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 4-hydroxycoumarin." [GOC:TermGenie, pmid:19757094] +synonym: "4-hydroxycoumarin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009804 ! coumarin metabolic process +created_by: ms +creation_date: 2013-02-06T14:05:50Z + +[Term] +id: GO:1901883 +name: 4-hydroxycoumarin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin." [GOC:TermGenie, pmid:19757094] +synonym: "4-hydroxycoumarin breakdown" EXACT [GOC:TermGenie] +synonym: "4-hydroxycoumarin catabolism" EXACT [GOC:TermGenie] +synonym: "4-hydroxycoumarin degradation" EXACT [GOC:TermGenie] +is_a: GO:0046226 ! coumarin catabolic process +is_a: GO:1901882 ! 4-hydroxycoumarin metabolic process +created_by: ms +creation_date: 2013-02-06T14:05:54Z + +[Term] +id: GO:1901884 +name: 4-hydroxycoumarin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin." [GOC:TermGenie, pmid:19757094] +synonym: "4-hydroxycoumarin anabolism" EXACT [GOC:TermGenie] +synonym: "4-hydroxycoumarin biosynthesis" EXACT [GOC:TermGenie] +synonym: "4-hydroxycoumarin formation" EXACT [GOC:TermGenie] +synonym: "4-hydroxycoumarin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009805 ! coumarin biosynthetic process +is_a: GO:1901882 ! 4-hydroxycoumarin metabolic process +created_by: ms +creation_date: 2013-02-06T14:05:59Z + +[Term] +id: GO:1901885 +name: 2-hydroxybenzoyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA." [GOC:TermGenie, pmid:19757094] +synonym: "2-hydroxybenzoyl-CoA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006637 ! acyl-CoA metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +created_by: ms +creation_date: 2013-02-06T14:06:03Z + +[Term] +id: GO:1901886 +name: 2-hydroxybenzoyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA." [GOC:TermGenie, pmid:19757094] +synonym: "2-hydroxybenzoyl-CoA breakdown" EXACT [GOC:TermGenie] +synonym: "2-hydroxybenzoyl-CoA catabolism" EXACT [GOC:TermGenie] +synonym: "2-hydroxybenzoyl-CoA degradation" EXACT [GOC:TermGenie] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901885 ! 2-hydroxybenzoyl-CoA metabolic process +created_by: ms +creation_date: 2013-02-06T14:06:08Z + +[Term] +id: GO:1901887 +name: 2-hydroxybenzoyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA." [GOC:TermGenie, pmid:19757094] +synonym: "2-hydroxybenzoyl-CoA anabolism" EXACT [GOC:TermGenie] +synonym: "2-hydroxybenzoyl-CoA biosynthesis" EXACT [GOC:TermGenie] +synonym: "2-hydroxybenzoyl-CoA formation" EXACT [GOC:TermGenie] +synonym: "2-hydroxybenzoyl-CoA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:0071616 ! acyl-CoA biosynthetic process +is_a: GO:1901885 ! 2-hydroxybenzoyl-CoA metabolic process +created_by: ms +creation_date: 2013-02-06T14:06:12Z + +[Term] +id: GO:1901888 +name: regulation of cell junction assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0034329 ! cell junction assembly +relationship: regulates GO:0034329 ! cell junction assembly +created_by: tb +creation_date: 2013-02-06T19:40:32Z + +[Term] +id: GO:1901889 +name: negative regulation of cell junction assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] +synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of cell junction assembly" NARROW [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0034329 ! cell junction assembly +relationship: negatively_regulates GO:0034329 ! cell junction assembly +created_by: tb +creation_date: 2013-02-06T19:40:41Z + +[Term] +id: GO:1901890 +name: positive regulation of cell junction assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] +synonym: "activation of cell junction assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0034329 ! cell junction assembly +relationship: positively_regulates GO:0034329 ! cell junction assembly +created_by: tb +creation_date: 2013-02-06T19:40:46Z + +[Term] +id: GO:1901891 +name: regulation of cell septum assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell septum assembly." [GOC:TermGenie] +is_a: GO:0032954 ! regulation of cytokinetic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090529 ! cell septum assembly +relationship: regulates GO:0090529 ! cell septum assembly +created_by: tb +creation_date: 2013-02-06T20:14:40Z + +[Term] +id: GO:1901892 +name: negative regulation of cell septum assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly." [GOC:TermGenie] +synonym: "down regulation of cell septum assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell septum assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cell septum assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of cell septum assembly" NARROW [GOC:TermGenie] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1901891 ! regulation of cell septum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090529 ! cell septum assembly +relationship: negatively_regulates GO:0090529 ! cell septum assembly +created_by: tb +creation_date: 2013-02-06T20:14:45Z + +[Term] +id: GO:1901893 +name: positive regulation of cell septum assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell septum assembly." [GOC:TermGenie] +synonym: "activation of cell septum assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of cell septum assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell septum assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of cell septum assembly" EXACT [GOC:TermGenie] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901891 ! regulation of cell septum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090529 ! cell septum assembly +relationship: positively_regulates GO:0090529 ! cell septum assembly +created_by: tb +creation_date: 2013-02-06T20:14:50Z + +[Term] +id: GO:1901894 +name: regulation of ATPase-coupled calcium transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +synonym: "regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "regulation of calcium-transporting ATPase activity" EXACT [] +synonym: "regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +relationship: regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +created_by: rl +creation_date: 2013-02-06T21:18:16Z + +[Term] +id: GO:1901895 +name: negative regulation of ATPase-coupled calcium transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +synonym: "down regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "down regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "down regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "down regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "down regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "down regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "down-regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "down-regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "down-regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "down-regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "down-regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "downregulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "downregulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "downregulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "downregulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "downregulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "downregulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "inhibition of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium pump" BROAD [GOC:TermGenie] +synonym: "inhibition of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium-transporting ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "inhibition of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "negative regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "negative regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "negative regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "negative regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of calcium-transporting ATPase activity" EXACT [] +synonym: "negative regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "negative regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:1901894 ! regulation of ATPase-coupled calcium transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +relationship: negatively_regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +created_by: rl +creation_date: 2013-02-06T21:18:25Z + +[Term] +id: GO:1901896 +name: positive regulation of ATPase-coupled calcium transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +synonym: "activation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "activation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "activation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "activation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "activation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "activation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "activation of calcium pump" BROAD [GOC:TermGenie] +synonym: "activation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "activation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of calcium-transporting ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "activation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "activation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "positive regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "positive regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium-transporting ATPase activity" EXACT [] +synonym: "positive regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "positive regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "up regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "up regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "up regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "up regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "up-regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "up-regulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "up-regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "up-regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +synonym: "upregulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] +synonym: "upregulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ABC transporter" NARROW [GOC:TermGenie] +synonym: "upregulation of calcium efflux ATPase" NARROW [GOC:TermGenie] +synonym: "upregulation of calcium pump" BROAD [GOC:TermGenie] +synonym: "upregulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] +synonym: "upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] +synonym: "upregulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:1901894 ! regulation of ATPase-coupled calcium transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +relationship: positively_regulates GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +created_by: rl +creation_date: 2013-02-06T21:18:29Z + +[Term] +id: GO:1901897 +name: regulation of relaxation of cardiac muscle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +is_a: GO:1901077 ! regulation of relaxation of muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055119 ! relaxation of cardiac muscle +relationship: regulates GO:0055119 ! relaxation of cardiac muscle +created_by: rl +creation_date: 2013-02-06T21:26:58Z + +[Term] +id: GO:1901898 +name: negative regulation of relaxation of cardiac muscle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +synonym: "down regulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +synonym: "down-regulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +synonym: "downregulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +synonym: "inhibition of relaxation of cardiac muscle" NARROW [GOC:TermGenie] +is_a: GO:1901078 ! negative regulation of relaxation of muscle +is_a: GO:1901897 ! regulation of relaxation of cardiac muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055119 ! relaxation of cardiac muscle +relationship: negatively_regulates GO:0055119 ! relaxation of cardiac muscle +created_by: rl +creation_date: 2013-02-06T21:27:02Z + +[Term] +id: GO:1901899 +name: positive regulation of relaxation of cardiac muscle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] +synonym: "activation of relaxation of cardiac muscle" NARROW [GOC:TermGenie] +synonym: "up regulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +synonym: "up-regulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +synonym: "upregulation of relaxation of cardiac muscle" EXACT [GOC:TermGenie] +is_a: GO:1901079 ! positive regulation of relaxation of muscle +is_a: GO:1901897 ! regulation of relaxation of cardiac muscle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055119 ! relaxation of cardiac muscle +relationship: positively_regulates GO:0055119 ! relaxation of cardiac muscle +created_by: rl +creation_date: 2013-02-06T21:27:07Z + +[Term] +id: GO:1901900 +name: regulation of protein localization to cell division site +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell division site." [GOC:dph, GOC:TermGenie, PMID:22573892] +synonym: "regulation of protein localisation to cell division site" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072741 ! protein localization to cell division site +relationship: regulates GO:0072741 ! protein localization to cell division site +created_by: dph +creation_date: 2013-02-11T12:27:55Z + +[Term] +id: GO:1901901 +name: regulation of protein localization to cell division site involved in cytokinesis +namespace: biological_process +def: "Any regulation of protein localization to cell division site that is involved in cytokinesis." [GOC:dph, GOC:TermGenie, PMID:22573892] +synonym: "regulation of protein localisation to cell division site involved in cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:1901900 ! regulation of protein localization to cell division site +intersection_of: GO:1901900 ! regulation of protein localization to cell division site +intersection_of: part_of GO:0000910 ! cytokinesis +relationship: part_of GO:0000910 ! cytokinesis +created_by: dph +creation_date: 2013-02-12T18:01:34Z + +[Term] +id: GO:1901902 +name: tyrocidine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tyrocidine." [GOC:TermGenie, GOC:yaf, PMID:9352938] +synonym: "tyrocidine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008152 ! metabolic process +created_by: yaf +creation_date: 2013-02-12T23:40:29Z + +[Term] +id: GO:1901903 +name: tyrocidine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of tyrocidine." [GOC:TermGenie, GOC:yaf, PMID:9352938] +synonym: "tyrocidine breakdown" EXACT [GOC:TermGenie] +synonym: "tyrocidine catabolism" EXACT [GOC:TermGenie] +synonym: "tyrocidine degradation" EXACT [GOC:TermGenie] +is_a: GO:0009056 ! catabolic process +is_a: GO:1901902 ! tyrocidine metabolic process +created_by: yaf +creation_date: 2013-02-12T23:40:34Z + +[Term] +id: GO:1901904 +name: tyrocidine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tyrocidine." [GOC:TermGenie, GOC:yaf, PMID:9352938, UniPathway:UPA00180] +synonym: "tyrocidine anabolism" EXACT [GOC:TermGenie] +synonym: "tyrocidine biosynthesis" EXACT [GOC:TermGenie] +synonym: "tyrocidine formation" EXACT [GOC:TermGenie] +synonym: "tyrocidine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:1901902 ! tyrocidine metabolic process +created_by: yaf +creation_date: 2013-02-12T23:40:43Z + +[Term] +id: GO:1901905 +name: response to tamsulosin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus." [GOC:TermGenie] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0014075 ! response to amine +is_a: GO:0045472 ! response to ether +is_a: GO:0097327 ! response to antineoplastic agent +created_by: hp +creation_date: 2013-02-13T10:14:41Z + +[Term] +id: GO:1901906 +name: diadenosine pentaphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diadenosine pentaphosphate." [GOC:TermGenie, PMID:10090752] +synonym: "diadenosine pentaphosphate metabolism" EXACT [GOC:pr] +synonym: "diadenosyl pentaphosphate metabolic process" EXACT [GOC:pr] +synonym: "diadenosyl pentaphosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process +created_by: al +creation_date: 2013-02-13T13:48:16Z + +[Term] +id: GO:1901907 +name: diadenosine pentaphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate." [GOC:TermGenie, PMID:10090752] +synonym: "diadenosine pentaphosphate catabolism" EXACT [GOC:pr] +synonym: "diadenosyl pentaphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "diadenosyl pentaphosphate catabolic process" EXACT [GOC:pr] +synonym: "diadenosyl pentaphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "diadenosyl pentaphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0015961 ! diadenosine polyphosphate catabolic process +is_a: GO:1901906 ! diadenosine pentaphosphate metabolic process +created_by: al +creation_date: 2013-02-13T13:48:21Z + +[Term] +id: GO:1901908 +name: diadenosine hexaphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving diadenosine hexaphosphate." [GOC:TermGenie, PMID:10090752] +synonym: "diadenosine hexaphosphate metabolism" EXACT [GOC:pr] +synonym: "diadenosyl hexaphosphate metabolic process" EXACT [GOC:pr] +synonym: "diadenosyl hexaphosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0015959 ! diadenosine polyphosphate metabolic process +created_by: al +creation_date: 2013-02-13T13:50:40Z + +[Term] +id: GO:1901909 +name: diadenosine hexaphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate." [GOC:TermGenie, PMID:10090752] +synonym: "diadenosine hexaphosphate catabolism" EXACT [GOC:pr] +synonym: "diadenosyl hexaphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "diadenosyl hexaphosphate catabolic process" EXACT [GOC:pr] +synonym: "diadenosyl hexaphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "diadenosyl hexaphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0015961 ! diadenosine polyphosphate catabolic process +is_a: GO:1901908 ! diadenosine hexaphosphate metabolic process +created_by: al +creation_date: 2013-02-13T13:50:44Z + +[Term] +id: GO:1901910 +name: adenosine 5'-(hexahydrogen pentaphosphate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate)." [GOC:TermGenie, PMID:10090752] +synonym: "adenosine 5'-(hexahydrogen pentaphosphate) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009150 ! purine ribonucleotide metabolic process +created_by: al +creation_date: 2013-02-13T14:17:59Z + +[Term] +id: GO:1901911 +name: adenosine 5'-(hexahydrogen pentaphosphate) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate)." [GOC:TermGenie, PMID:10090752] +synonym: "adenosine 5'-(hexahydrogen pentaphosphate) breakdown" EXACT [GOC:TermGenie] +synonym: "adenosine 5'-(hexahydrogen pentaphosphate) catabolism" EXACT [GOC:TermGenie] +synonym: "adenosine 5'-(hexahydrogen pentaphosphate) degradation" EXACT [GOC:TermGenie] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:1901910 ! adenosine 5'-(hexahydrogen pentaphosphate) metabolic process +created_by: al +creation_date: 2013-02-13T14:18:03Z + +[Term] +id: GO:1901913 +name: regulation of capsule organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of capsule organization." [GOC:di, GOC:TermGenie] +synonym: "regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045230 ! capsule organization +relationship: regulates GO:0045230 ! capsule organization +created_by: di +creation_date: 2013-02-14T06:19:03Z + +[Term] +id: GO:1901914 +name: negative regulation of capsule organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization." [GOC:di, GOC:TermGenie] +synonym: "down regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "down regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "downregulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of capsule organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of capsule organization" NARROW [GOC:TermGenie] +synonym: "inhibition of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1901913 ! regulation of capsule organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045230 ! capsule organization +relationship: negatively_regulates GO:0045230 ! capsule organization +created_by: di +creation_date: 2013-02-14T06:19:07Z + +[Term] +id: GO:1901915 +name: positive regulation of capsule organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of capsule organization." [GOC:di, GOC:TermGenie] +synonym: "activation of capsule organisation" NARROW [GOC:TermGenie] +synonym: "activation of capsule organization" NARROW [GOC:TermGenie] +synonym: "activation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "up regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of capsule organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of capsule organization" EXACT [GOC:TermGenie] +synonym: "upregulation of capsule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1901913 ! regulation of capsule organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045230 ! capsule organization +relationship: positively_regulates GO:0045230 ! capsule organization +created_by: di +creation_date: 2013-02-14T06:19:16Z + +[Term] +id: GO:1901916 +name: protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis +namespace: molecular_function +def: "Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis." [GOC:dph, GOC:TermGenie, PMID:22573892] +synonym: "protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis" NARROW [GOC:TermGenie] +synonym: "protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis" NARROW [GOC:TermGenie] +synonym: "protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0004672 ! protein kinase activity +intersection_of: GO:0004672 ! protein kinase activity +intersection_of: part_of GO:1901901 ! regulation of protein localization to cell division site involved in cytokinesis +relationship: part_of GO:1901901 ! regulation of protein localization to cell division site involved in cytokinesis +created_by: dph +creation_date: 2013-02-14T15:30:37Z + +[Term] +id: GO:1901917 +name: regulation of exoribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exoribonuclease activity." [GOC:TermGenie, PMID:22570495] +is_a: GO:0060700 ! regulation of ribonuclease activity +is_a: GO:1905777 ! regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004532 ! exoribonuclease activity +relationship: regulates GO:0004532 ! exoribonuclease activity +created_by: rb +creation_date: 2013-02-15T00:57:56Z + +[Term] +id: GO:1901918 +name: negative regulation of exoribonuclease activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity." [GOC:TermGenie, PMID:22570495] +synonym: "down regulation of exoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of exoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "downregulation of exoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "inhibition of exoribonuclease activity" NARROW [GOC:TermGenie] +is_a: GO:0060701 ! negative regulation of ribonuclease activity +is_a: GO:1901917 ! regulation of exoribonuclease activity +is_a: GO:1905778 ! negative regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004532 ! exoribonuclease activity +relationship: negatively_regulates GO:0004532 ! exoribonuclease activity +created_by: rb +creation_date: 2013-02-15T00:58:03Z + +[Term] +id: GO:1901919 +name: positive regulation of exoribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exoribonuclease activity." [GOC:TermGenie, PMID:22570495] +synonym: "activation of exoribonuclease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of exoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of exoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "upregulation of exoribonuclease activity" EXACT [GOC:TermGenie] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1901917 ! regulation of exoribonuclease activity +is_a: GO:1905779 ! positive regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004532 ! exoribonuclease activity +relationship: positively_regulates GO:0004532 ! exoribonuclease activity +created_by: rb +creation_date: 2013-02-15T00:58:07Z + +[Term] +id: GO:1901920 +name: peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity +namespace: biological_process +def: "Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity." [GOC:TermGenie, PMID:1756737] +synonym: "peptidyl-tyrosine dephosphorylation involved in protein kinase activation" RELATED [GOC:TermGenie] +is_a: GO:0035335 ! peptidyl-tyrosine dephosphorylation +intersection_of: GO:0035335 ! peptidyl-tyrosine dephosphorylation +intersection_of: part_of GO:0032147 ! activation of protein kinase activity +relationship: part_of GO:0032147 ! activation of protein kinase activity +created_by: al +creation_date: 2013-02-15T18:54:53Z + +[Term] +id: GO:1901921 +name: phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex +namespace: biological_process +def: "Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex." [GOC:TermGenie, PMID:10594013] +synonym: "CTD domain phosphorylation of RNA polymerase II involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex" EXACT [GOC:TermGenie] +is_a: GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +intersection_of: GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain +intersection_of: part_of GO:0034402 ! recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex +relationship: part_of GO:0034402 ! recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex +created_by: rb +creation_date: 2013-02-15T19:09:31Z + +[Term] +id: GO:1901922 +name: regulation of sclerotium development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sclerotium development." [GOC:di, GOC:TermGenie, PMID:21148914] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990045 ! sclerotium development +relationship: regulates GO:1990045 ! sclerotium development +created_by: di +creation_date: 2013-02-15T20:00:19Z + +[Term] +id: GO:1901923 +name: negative regulation of sclerotium development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development." [GOC:di, GOC:TermGenie, PMID:21148914] +synonym: "down regulation of sclerotium development" EXACT [GOC:TermGenie] +synonym: "down-regulation of sclerotium development" EXACT [GOC:TermGenie] +synonym: "downregulation of sclerotium development" EXACT [GOC:TermGenie] +synonym: "inhibition of sclerotium development" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1901922 ! regulation of sclerotium development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990045 ! sclerotium development +relationship: negatively_regulates GO:1990045 ! sclerotium development +created_by: di +creation_date: 2013-02-15T20:00:23Z + +[Term] +id: GO:1901924 +name: positive regulation of sclerotium development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sclerotium development." [GOC:di, GOC:TermGenie, PMID:21148914] +synonym: "activation of sclerotium development" NARROW [GOC:TermGenie] +synonym: "up regulation of sclerotium development" EXACT [GOC:TermGenie] +synonym: "up-regulation of sclerotium development" EXACT [GOC:TermGenie] +synonym: "upregulation of sclerotium development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1901922 ! regulation of sclerotium development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990045 ! sclerotium development +relationship: positively_regulates GO:1990045 ! sclerotium development +created_by: di +creation_date: 2013-02-15T20:00:28Z + +[Term] +id: GO:1901925 +name: negative regulation of protein import into nucleus during spindle assembly checkpoint +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p)." [GOC:dgf, GOC:TermGenie, PMID:23177738] +synonym: "Kap121p transport inhibitory pathway" RELATED [] +synonym: "KTIP" RELATED [] +synonym: "negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint" EXACT [] +is_a: GO:0072479 ! response to mitotic cell cycle spindle assembly checkpoint signaling +created_by: pr +creation_date: 2013-02-17T20:55:16Z + +[Term] +id: GO:1901926 +name: cadinene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cadinene." [GOC:TermGenie, pmid:22867794] +synonym: "cadinene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051761 ! sesquiterpene metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:22Z + +[Term] +id: GO:1901927 +name: cadinene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cadinene." [GOC:TermGenie, pmid:22867794] +synonym: "cadinene breakdown" EXACT [GOC:TermGenie] +synonym: "cadinene catabolism" EXACT [GOC:TermGenie] +synonym: "cadinene degradation" EXACT [GOC:TermGenie] +is_a: GO:0051763 ! sesquiterpene catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901926 ! cadinene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:29Z + +[Term] +id: GO:1901928 +name: cadinene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cadinene." [GOC:TermGenie, pmid:22867794] +synonym: "cadinene anabolism" EXACT [GOC:TermGenie] +synonym: "cadinene biosynthesis" EXACT [GOC:TermGenie] +synonym: "cadinene formation" EXACT [GOC:TermGenie] +synonym: "cadinene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051762 ! sesquiterpene biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901926 ! cadinene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:34Z + +[Term] +id: GO:1901929 +name: alpha-copaene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving alpha-copaene." [GOC:TermGenie, pmid:22867794] +synonym: "alpha-copaene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051761 ! sesquiterpene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:39Z + +[Term] +id: GO:1901930 +name: alpha-copaene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of alpha-copaene." [GOC:TermGenie, pmid:22867794] +synonym: "alpha-copaene breakdown" EXACT [GOC:TermGenie] +synonym: "alpha-copaene catabolism" EXACT [GOC:TermGenie] +synonym: "alpha-copaene degradation" EXACT [GOC:TermGenie] +is_a: GO:0051763 ! sesquiterpene catabolic process +is_a: GO:1901929 ! alpha-copaene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:43Z + +[Term] +id: GO:1901931 +name: alpha-copaene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of alpha-copaene." [GOC:TermGenie, pmid:22867794] +synonym: "alpha-copaene anabolism" EXACT [GOC:TermGenie] +synonym: "alpha-copaene biosynthesis" EXACT [GOC:TermGenie] +synonym: "alpha-copaene formation" EXACT [GOC:TermGenie] +synonym: "alpha-copaene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051762 ! sesquiterpene biosynthetic process +is_a: GO:1901929 ! alpha-copaene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:48Z + +[Term] +id: GO:1901932 +name: bicyclogermacrene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bicyclogermacrene." [GOC:TermGenie, pmid:22867794] +synonym: "bicyclogermacrene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051761 ! sesquiterpene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:52Z + +[Term] +id: GO:1901933 +name: bicyclogermacrene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene." [GOC:TermGenie, pmid:22867794] +synonym: "bicyclogermacrene breakdown" EXACT [GOC:TermGenie] +synonym: "bicyclogermacrene catabolism" EXACT [GOC:TermGenie] +synonym: "bicyclogermacrene degradation" EXACT [GOC:TermGenie] +is_a: GO:0051763 ! sesquiterpene catabolic process +is_a: GO:1901932 ! bicyclogermacrene metabolic process +created_by: ms +creation_date: 2013-02-18T14:54:57Z + +[Term] +id: GO:1901934 +name: bicyclogermacrene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of bicyclogermacrene." [GOC:TermGenie, pmid:22867794] +synonym: "bicyclogermacrene anabolism" EXACT [GOC:TermGenie] +synonym: "bicyclogermacrene biosynthesis" EXACT [GOC:TermGenie] +synonym: "bicyclogermacrene formation" EXACT [GOC:TermGenie] +synonym: "bicyclogermacrene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051762 ! sesquiterpene biosynthetic process +is_a: GO:1901932 ! bicyclogermacrene metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:01Z + +[Term] +id: GO:1901935 +name: beta-caryophyllene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving beta-caryophyllene." [GOC:TermGenie, pmid:22867794] +synonym: "beta-caryophyllene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051761 ! sesquiterpene metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:06Z + +[Term] +id: GO:1901936 +name: beta-caryophyllene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene." [GOC:TermGenie, pmid:22867794] +synonym: "beta-caryophyllene breakdown" EXACT [GOC:TermGenie] +synonym: "beta-caryophyllene catabolism" EXACT [GOC:TermGenie] +synonym: "beta-caryophyllene degradation" EXACT [GOC:TermGenie] +is_a: GO:0051763 ! sesquiterpene catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901935 ! beta-caryophyllene metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:13Z + +[Term] +id: GO:1901937 +name: beta-caryophyllene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of beta-caryophyllene." [GOC:TermGenie, pmid:22867794] +synonym: "beta-caryophyllene anabolism" EXACT [GOC:TermGenie] +synonym: "beta-caryophyllene biosynthesis" EXACT [GOC:TermGenie] +synonym: "beta-caryophyllene formation" EXACT [GOC:TermGenie] +synonym: "beta-caryophyllene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051762 ! sesquiterpene biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901935 ! beta-caryophyllene metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:18Z + +[Term] +id: GO:1901938 +name: (-)-exo-alpha-bergamotene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-exo-alpha-bergamotene." [GOC:TermGenie, pmid:22867794] +synonym: "(-)-exo-alpha-bergamotene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051761 ! sesquiterpene metabolic process +is_a: GO:1900673 ! olefin metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:23Z + +[Term] +id: GO:1901939 +name: (-)-exo-alpha-bergamotene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene." [GOC:TermGenie, pmid:22867794] +synonym: "(-)-exo-alpha-bergamotene breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-exo-alpha-bergamotene catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-exo-alpha-bergamotene degradation" EXACT [GOC:TermGenie] +is_a: GO:0051763 ! sesquiterpene catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901938 ! (-)-exo-alpha-bergamotene metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:27Z + +[Term] +id: GO:1901940 +name: (-)-exo-alpha-bergamotene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene." [GOC:TermGenie, pmid:22867794] +synonym: "(-)-exo-alpha-bergamotene anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-exo-alpha-bergamotene biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-exo-alpha-bergamotene formation" EXACT [GOC:TermGenie] +synonym: "(-)-exo-alpha-bergamotene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051762 ! sesquiterpene biosynthetic process +is_a: GO:1900674 ! olefin biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901938 ! (-)-exo-alpha-bergamotene metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:32Z + +[Term] +id: GO:1901941 +name: (+)-epi-alpha-bisabolol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-epi-alpha-bisabolol." [GOC:TermGenie, pmid:22867794] +synonym: "(+)-epi-alpha-bisabolol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006714 ! sesquiterpenoid metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:36Z + +[Term] +id: GO:1901942 +name: (+)-epi-alpha-bisabolol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol." [GOC:TermGenie, pmid:22867794] +synonym: "(+)-epi-alpha-bisabolol breakdown" EXACT [GOC:TermGenie] +synonym: "(+)-epi-alpha-bisabolol catabolism" EXACT [GOC:TermGenie] +synonym: "(+)-epi-alpha-bisabolol degradation" EXACT [GOC:TermGenie] +is_a: GO:0016107 ! sesquiterpenoid catabolic process +is_a: GO:1901941 ! (+)-epi-alpha-bisabolol metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:41Z + +[Term] +id: GO:1901943 +name: (+)-epi-alpha-bisabolol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol." [GOC:TermGenie, pmid:22867794] +synonym: "(+)-epi-alpha-bisabolol anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-epi-alpha-bisabolol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-epi-alpha-bisabolol formation" EXACT [GOC:TermGenie] +synonym: "(+)-epi-alpha-bisabolol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016106 ! sesquiterpenoid biosynthetic process +is_a: GO:1901941 ! (+)-epi-alpha-bisabolol metabolic process +created_by: ms +creation_date: 2013-02-18T14:55:46Z + +[Term] +id: GO:1901944 +name: miltiradiene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving miltiradiene." [GOC:TermGenie, pmid:22027823] +synonym: "miltiradiene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042214 ! terpene metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:23Z + +[Term] +id: GO:1901945 +name: miltiradiene catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of miltiradiene." [GOC:TermGenie, pmid:22027823] +synonym: "miltiradiene breakdown" EXACT [GOC:TermGenie] +synonym: "miltiradiene catabolism" EXACT [GOC:TermGenie] +synonym: "miltiradiene degradation" EXACT [GOC:TermGenie] +is_a: GO:0046247 ! terpene catabolic process +is_a: GO:1901944 ! miltiradiene metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:27Z + +[Term] +id: GO:1901946 +name: miltiradiene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of miltiradiene." [GOC:TermGenie, pmid:22027823] +synonym: "miltiradiene anabolism" EXACT [GOC:TermGenie] +synonym: "miltiradiene biosynthesis" EXACT [GOC:TermGenie] +synonym: "miltiradiene formation" EXACT [GOC:TermGenie] +synonym: "miltiradiene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046246 ! terpene biosynthetic process +is_a: GO:1901944 ! miltiradiene metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:32Z + +[Term] +id: GO:1901947 +name: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate." [GOC:TermGenie, pmid:22027823] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:41Z + +[Term] +id: GO:1901948 +name: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate." [GOC:TermGenie, pmid:22027823] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0016103 ! diterpenoid catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901947 ! 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:45Z + +[Term] +id: GO:1901949 +name: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate." [GOC:TermGenie, pmid:22027823] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate formation" EXACT [GOC:TermGenie] +synonym: "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901947 ! 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process +created_by: ms +creation_date: 2013-02-18T15:50:50Z + +[Term] +id: GO:1901950 +name: dense core granule transport +namespace: biological_process +def: "The directed movement a dense core granule within a cell." [GOC:kmv, GOC:TermGenie, PMID:23358451] +comment: goslim_synapse +synonym: "dense core vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:0016482 ! cytosolic transport +is_a: GO:0032253 ! dense core granule localization +is_a: GO:0051650 ! establishment of vesicle localization +created_by: pr +creation_date: 2013-02-19T13:00:52Z + +[Term] +id: GO:1901951 +name: regulation of anterograde dense core granule transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +is_a: GO:1901608 ! regulation of vesicle transport along microtubule +is_a: GO:1904809 ! regulation of dense core granule transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +relationship: regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:21Z + +[Term] +id: GO:1901952 +name: negative regulation of anterograde dense core granule transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +synonym: "down regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "downregulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "inhibition of anterograde dense core granule transport" NARROW [GOC:TermGenie] +is_a: GO:1901609 ! negative regulation of vesicle transport along microtubule +is_a: GO:1901951 ! regulation of anterograde dense core granule transport +is_a: GO:1904810 ! negative regulation of dense core granule transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +relationship: negatively_regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:30Z + +[Term] +id: GO:1901953 +name: positive regulation of anterograde dense core granule transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +synonym: "activation of anterograde dense core granule transport" NARROW [GOC:TermGenie] +synonym: "up regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "upregulation of anterograde dense core granule transport" EXACT [GOC:TermGenie] +is_a: GO:1901610 ! positive regulation of vesicle transport along microtubule +is_a: GO:1901951 ! regulation of anterograde dense core granule transport +is_a: GO:1904811 ! positive regulation of dense core granule transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +relationship: positively_regulates GO:1990048 ! anterograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:35Z + +[Term] +id: GO:1901954 +name: regulation of retrograde dense core granule transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +is_a: GO:1901608 ! regulation of vesicle transport along microtubule +is_a: GO:1904809 ! regulation of dense core granule transport +is_a: GO:2001017 ! regulation of retrograde axon cargo transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +relationship: regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:43Z + +[Term] +id: GO:1901955 +name: negative regulation of retrograde dense core granule transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +synonym: "down regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "inhibition of retrograde dense core granule transport" NARROW [GOC:TermGenie] +is_a: GO:1901609 ! negative regulation of vesicle transport along microtubule +is_a: GO:1901954 ! regulation of retrograde dense core granule transport +is_a: GO:1904810 ! negative regulation of dense core granule transport +is_a: GO:2001018 ! negative regulation of retrograde axon cargo transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +relationship: negatively_regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:47Z + +[Term] +id: GO:1901956 +name: positive regulation of retrograde dense core granule transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport." [GOC:kmv, GOC:TermGenie, PMID:23358451] +synonym: "activation of retrograde dense core granule transport" NARROW [GOC:TermGenie] +synonym: "up regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde dense core granule transport" EXACT [GOC:TermGenie] +is_a: GO:1901610 ! positive regulation of vesicle transport along microtubule +is_a: GO:1901954 ! regulation of retrograde dense core granule transport +is_a: GO:1904811 ! positive regulation of dense core granule transport +is_a: GO:2001019 ! positive regulation of retrograde axon cargo transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +relationship: positively_regulates GO:1990049 ! retrograde neuronal dense core vesicle transport +created_by: pr +creation_date: 2013-02-19T13:36:52Z + +[Term] +id: GO:1901957 +name: regulation of cutin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cutin biosynthetic process." [GOC:tb, GOC:TermGenie, PMID:23243127] +synonym: "regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "regulation of cutin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010143 ! cutin biosynthetic process +relationship: regulates GO:0010143 ! cutin biosynthetic process +created_by: tb +creation_date: 2013-02-19T19:06:06Z + +[Term] +id: GO:1901958 +name: negative regulation of cutin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process." [GOC:tb, GOC:TermGenie, PMID:23243127] +synonym: "down regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cutin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of cutin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of cutin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:1901957 ! regulation of cutin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010143 ! cutin biosynthetic process +relationship: negatively_regulates GO:0010143 ! cutin biosynthetic process +created_by: tb +creation_date: 2013-02-19T19:06:10Z + +[Term] +id: GO:1901959 +name: positive regulation of cutin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process." [GOC:tb, GOC:TermGenie, PMID:23243127] +synonym: "activation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of cutin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of cutin formation" EXACT [GOC:TermGenie] +synonym: "activation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cutin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cutin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of cutin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cutin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cutin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of cutin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:1901957 ! regulation of cutin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010143 ! cutin biosynthetic process +relationship: positively_regulates GO:0010143 ! cutin biosynthetic process +created_by: tb +creation_date: 2013-02-19T19:06:19Z + +[Term] +id: GO:1901960 +name: isobutanol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isobutanol." [GOC:mengo_curators, GOC:TermGenie, PMID:22224870] +synonym: "isobutanol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0034308 ! primary alcohol metabolic process +created_by: tt +creation_date: 2013-02-19T21:49:44Z + +[Term] +id: GO:1901961 +name: isobutanol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isobutanol." [GOC:mengo_curators, GOC:TermGenie, PMID:22224870] +synonym: "isobutanol anabolism" EXACT [GOC:TermGenie] +synonym: "isobutanol biosynthesis" EXACT [GOC:TermGenie] +synonym: "isobutanol formation" EXACT [GOC:TermGenie] +synonym: "isobutanol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:1901960 ! isobutanol metabolic process +created_by: tt +creation_date: 2013-02-19T21:49:49Z + +[Term] +id: GO:1901962 +name: S-adenosyl-L-methionine transmembrane transport +namespace: biological_process +def: "The directed movement of S-adenosyl-L-methionine across a membrane." [GOC:TermGenie, PMID:10497160] +synonym: "S-adenosylmethionine transmembrane transport" EXACT [] +synonym: "SAM transmembrane transport" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015805 ! S-adenosyl-L-methionine transport +created_by: jl +creation_date: 2013-02-20T14:45:08Z + +[Term] +id: GO:1901963 +name: regulation of cell proliferation involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] +is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis +relationship: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis +created_by: dph +creation_date: 2013-02-20T20:30:26Z + +[Term] +id: GO:1901964 +name: positive regulation of cell proliferation involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] +synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis +is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis +relationship: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis +created_by: dph +creation_date: 2013-02-20T20:30:31Z + +[Term] +id: GO:1901965 +name: endoplasmic reticulum to chloroplast transport +namespace: biological_process +def: "The directed movement of substances from endoplasmic reticulum to chloroplast." [GOC:TermGenie, PMID:18689504] +synonym: "ER to chloroplast transport" EXACT [GOC:TermGenie] +is_a: GO:0046907 ! intracellular transport +created_by: tb +creation_date: 2013-02-20T23:48:52Z + +[Term] +id: GO:1901966 +name: regulation of cellular response to iron ion starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation." [GOC:TermGenie, PMID:23115244] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0065008 ! regulation of biological quality +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010106 ! cellular response to iron ion starvation +relationship: regulates GO:0010106 ! cellular response to iron ion starvation +created_by: al +creation_date: 2013-02-21T11:35:57Z + +[Term] +id: GO:1901967 +name: negative regulation of cellular response to iron ion starvation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation." [GOC:TermGenie, PMID:23115244] +synonym: "down regulation of cellular response to iron ion starvation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to iron ion starvation" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to iron ion starvation" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to iron ion starvation" NARROW [GOC:TermGenie] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:1901966 ! regulation of cellular response to iron ion starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010106 ! cellular response to iron ion starvation +relationship: negatively_regulates GO:0010106 ! cellular response to iron ion starvation +created_by: al +creation_date: 2013-02-21T11:36:02Z + +[Term] +id: GO:1901968 +name: regulation of polynucleotide 3'-phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity." [GOC:TermGenie, PMID:23316050] +synonym: "regulation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0010921 ! regulation of phosphatase activity +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046403 ! polynucleotide 3'-phosphatase activity +relationship: regulates GO:0046403 ! polynucleotide 3'-phosphatase activity +created_by: tb +creation_date: 2013-02-22T00:58:17Z + +[Term] +id: GO:1901969 +name: positive regulation of polynucleotide 3'-phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity." [GOC:TermGenie, PMID:23316050] +synonym: "activation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "activation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "activation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "activation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "activation of polynucleotide 3'-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polynucleotide 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polynucleotide 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 2'(3')-polynucleotidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5'-polynucleotidekinase 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleate 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polynucleotide 3'-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polynucleotide 3'-phosphohydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:1901968 ! regulation of polynucleotide 3'-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046403 ! polynucleotide 3'-phosphatase activity +relationship: positively_regulates GO:0046403 ! polynucleotide 3'-phosphatase activity +created_by: tb +creation_date: 2013-02-22T00:58:31Z + +[Term] +id: GO:1901970 +name: positive regulation of mitotic sister chromatid separation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation." [GOC:TermGenie, PMID:1846086] +synonym: "activation of chromosome separation during mitosis" RELATED [GOC:TermGenie] +synonym: "activation of mitotic chromosome separation" RELATED [GOC:TermGenie] +synonym: "activation of mitotic sister chromatid resolution" EXACT [GOC:TermGenie] +synonym: "activation of mitotic sister chromatid separation" NARROW [GOC:TermGenie] +synonym: "activation of sister chromatid separation during mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chromosome separation during mitosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitotic chromosome separation" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitotic sister chromatid resolution" EXACT [GOC:TermGenie] +synonym: "positive regulation of sister chromatid separation during mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of chromosome separation during mitosis" RELATED [GOC:TermGenie] +synonym: "up regulation of mitotic chromosome separation" RELATED [GOC:TermGenie] +synonym: "up regulation of mitotic sister chromatid resolution" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic sister chromatid separation" EXACT [GOC:TermGenie] +synonym: "up regulation of sister chromatid separation during mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromosome separation during mitosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of mitotic chromosome separation" RELATED [GOC:TermGenie] +synonym: "up-regulation of mitotic sister chromatid resolution" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic sister chromatid separation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sister chromatid separation during mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of chromosome separation during mitosis" RELATED [GOC:TermGenie] +synonym: "upregulation of mitotic chromosome separation" RELATED [GOC:TermGenie] +synonym: "upregulation of mitotic sister chromatid resolution" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic sister chromatid separation" EXACT [GOC:TermGenie] +synonym: "upregulation of sister chromatid separation during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0010965 ! regulation of mitotic sister chromatid separation +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +is_a: GO:1905820 ! positive regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051306 ! mitotic sister chromatid separation +relationship: positively_regulates GO:0051306 ! mitotic sister chromatid separation +created_by: al +creation_date: 2013-02-22T19:06:19Z + +[Term] +id: GO:1901971 +name: regulation of DNA-5-methylcytosine glycosylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity." [GOC:TermGenie, PMID:23316050] +is_a: GO:1902544 ! regulation of DNA N-glycosylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990053 ! DNA-5-methylcytosine glycosylase activity +relationship: regulates GO:1990053 ! DNA-5-methylcytosine glycosylase activity +created_by: tb +creation_date: 2013-02-25T20:01:29Z + +[Term] +id: GO:1901972 +name: positive regulation of DNA-5-methylcytosine glycosylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity." [GOC:TermGenie, PMID:23316050] +synonym: "activation of DNA-5-methylcytosine glycosylase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA-5-methylcytosine glycosylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA-5-methylcytosine glycosylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA-5-methylcytosine glycosylase activity" EXACT [GOC:TermGenie] +is_a: GO:1901971 ! regulation of DNA-5-methylcytosine glycosylase activity +is_a: GO:1902546 ! positive regulation of DNA N-glycosylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990053 ! DNA-5-methylcytosine glycosylase activity +relationship: positively_regulates GO:1990053 ! DNA-5-methylcytosine glycosylase activity +created_by: tb +creation_date: 2013-02-25T20:01:34Z + +[Term] +id: GO:1901973 +name: proline binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with proline." [GOC:pm, GOC:TermGenie, PMID:7730362] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: pm +creation_date: 2013-02-26T14:58:01Z + +[Term] +id: GO:1901974 +name: glycerate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of glycerate from one side of a membrane to the other." [GOC:TermGenie, pmid:23382251] +is_a: GO:0042879 ! aldonate transmembrane transporter activity +relationship: part_of GO:1901975 ! glycerate transmembrane transport +created_by: ms +creation_date: 2013-03-05T16:48:45Z + +[Term] +id: GO:1901975 +name: glycerate transmembrane transport +namespace: biological_process +def: "The process in which glycerate is transported across a membrane." [GOC:TermGenie, pmid:23382251] +is_a: GO:0042873 ! aldonate transmembrane transport +created_by: ms +creation_date: 2013-03-05T16:48:50Z + +[Term] +id: GO:1901976 +name: regulation of cell cycle checkpoint +namespace: biological_process +alt_id: GO:2001047 +def: "Any process that modulates the frequency, rate or extent of cell cycle checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:23028116] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc). +subset: gocheck_do_not_manually_annotate +synonym: "regulation of G1/S checkpoint" RELATED [GOC:obol] +synonym: "regulation of G1/S transition checkpoint" RELATED [] +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000075 ! cell cycle checkpoint +relationship: regulates GO:0000075 ! cell cycle checkpoint +created_by: jl +creation_date: 2013-03-06T15:10:20Z + +[Term] +id: GO:1901977 +name: negative regulation of cell cycle checkpoint +namespace: biological_process +alt_id: GO:2001048 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:23028116] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc). +subset: gocheck_do_not_manually_annotate +synonym: "down regulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "inhibition of cell cycle checkpoint" NARROW [GOC:TermGenie] +synonym: "negative regulation of G1/S checkpoint" RELATED [GOC:obol] +synonym: "negative regulation of G1/S transition checkpoint" RELATED [] +is_a: GO:0045787 ! positive regulation of cell cycle +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1901976 ! regulation of cell cycle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000075 ! cell cycle checkpoint +relationship: negatively_regulates GO:0000075 ! cell cycle checkpoint +created_by: jl +creation_date: 2013-03-06T15:10:29Z + +[Term] +id: GO:1901978 +name: positive regulation of cell cycle checkpoint +namespace: biological_process +alt_id: GO:2001052 +def: "Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:23028116] +synonym: "activation of cell cycle checkpoint" NARROW [GOC:TermGenie] +synonym: "positive regulation of G1/S checkpoint" RELATED [GOC:obol] +synonym: "positive regulation of G1/S transition checkpoint" RELATED [] +synonym: "up regulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1901976 ! regulation of cell cycle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000075 ! cell cycle checkpoint +relationship: positively_regulates GO:0000075 ! cell cycle checkpoint +created_by: jl +creation_date: 2013-03-06T15:10:34Z + +[Term] +id: GO:1901979 +name: regulation of inward rectifier potassium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity." [GOC:TermGenie, PMID:23449501] +synonym: "regulation of Kir channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005242 ! inward rectifier potassium channel activity +relationship: regulates GO:0005242 ! inward rectifier potassium channel activity +created_by: tb +creation_date: 2013-03-12T18:21:12Z + +[Term] +id: GO:1901980 +name: positive regulation of inward rectifier potassium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity." [GOC:TermGenie, PMID:23449501] +synonym: "activation of inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Kir channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity +is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005242 ! inward rectifier potassium channel activity +relationship: positively_regulates GO:0005242 ! inward rectifier potassium channel activity +created_by: tb +creation_date: 2013-03-12T18:21:17Z + +[Term] +id: GO:1901981 +name: phosphatidylinositol phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol phosphate." [GOC:TermGenie, PMID:23445487] +is_a: GO:0035091 ! phosphatidylinositol binding +created_by: tb +creation_date: 2013-03-12T18:21:22Z + +[Term] +id: GO:1901982 +name: maltose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with maltose." [GOC:TermGenie, PMID:21566157] +is_a: GO:0048030 ! disaccharide binding +created_by: tb +creation_date: 2013-03-13T18:17:19Z + +[Term] +id: GO:1901983 +name: regulation of protein acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] +synonym: "regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006473 ! protein acetylation +relationship: regulates GO:0006473 ! protein acetylation +created_by: ss +creation_date: 2013-03-14T00:40:07Z + +[Term] +id: GO:1901984 +name: negative regulation of protein acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] +synonym: "down regulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein acetylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein amino acid acetylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1901983 ! regulation of protein acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006473 ! protein acetylation +relationship: negatively_regulates GO:0006473 ! protein acetylation +created_by: ss +creation_date: 2013-03-14T00:40:11Z + +[Term] +id: GO:1901985 +name: positive regulation of protein acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] +synonym: "activation of protein acetylation" NARROW [GOC:TermGenie] +synonym: "activation of protein amino acid acetylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein amino acid acetylation" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1901983 ! regulation of protein acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006473 ! protein acetylation +relationship: positively_regulates GO:0006473 ! protein acetylation +created_by: ss +creation_date: 2013-03-14T00:40:19Z + +[Term] +id: GO:1901986 +name: response to ketamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus." [GOC:TermGenie, PMID:11251190] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0072347 ! response to anesthetic +is_a: GO:1901654 ! response to ketone +created_by: dph +creation_date: 2013-03-15T19:16:35Z + +[Term] +id: GO:1901987 +name: regulation of cell cycle phase transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "cell cycle control" EXACT [GOC:vw] +synonym: "regulation of cell cycle transition" EXACT [GOC:TermGenie] +is_a: GO:0010564 ! regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044770 ! cell cycle phase transition +relationship: regulates GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:11:27Z + +[Term] +id: GO:1901988 +name: negative regulation of cell cycle phase transition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "down regulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "down regulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "inhibition of cell cycle phase transition" NARROW [GOC:TermGenie] +synonym: "inhibition of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell cycle transition" EXACT [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044770 ! cell cycle phase transition +relationship: negatively_regulates GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:11:32Z + +[Term] +id: GO:1901989 +name: positive regulation of cell cycle phase transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "activation of cell cycle phase transition" NARROW [GOC:TermGenie] +synonym: "activation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "up regulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "up regulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle transition" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle transition" EXACT [GOC:TermGenie] +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044770 ! cell cycle phase transition +relationship: positively_regulates GO:0044770 ! cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:11:37Z + +[Term] +id: GO:1901990 +name: regulation of mitotic cell cycle phase transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +subset: goslim_pombe +synonym: "mitotic cell cycle control" EXACT [GOC:vw] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044772 ! mitotic cell cycle phase transition +relationship: regulates GO:0044772 ! mitotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:14:38Z + +[Term] +id: GO:1901991 +name: negative regulation of mitotic cell cycle phase transition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "down regulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic cell cycle phase transition" NARROW [GOC:TermGenie] +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:1901988 ! negative regulation of cell cycle phase transition +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044772 ! mitotic cell cycle phase transition +relationship: negatively_regulates GO:0044772 ! mitotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:14:46Z + +[Term] +id: GO:1901992 +name: positive regulation of mitotic cell cycle phase transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "activation of mitotic cell cycle phase transition" NARROW [GOC:TermGenie] +synonym: "up regulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic cell cycle phase transition" EXACT [GOC:TermGenie] +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:1901989 ! positive regulation of cell cycle phase transition +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044772 ! mitotic cell cycle phase transition +relationship: positively_regulates GO:0044772 ! mitotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:14:51Z + +[Term] +id: GO:1901993 +name: regulation of meiotic cell cycle phase transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "meiotic cell cycle control" EXACT [GOC:vw] +synonym: "regulation of cell cycle transition" BROAD [GOC:TermGenie] +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044771 ! meiotic cell cycle phase transition +relationship: regulates GO:0044771 ! meiotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:14:58Z + +[Term] +id: GO:1901994 +name: negative regulation of meiotic cell cycle phase transition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "down regulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "down regulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "down-regulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "downregulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "inhibition of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "inhibition of meiotic cell cycle phase transition" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell cycle transition" BROAD [GOC:TermGenie] +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:1901988 ! negative regulation of cell cycle phase transition +is_a: GO:1901993 ! regulation of meiotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044771 ! meiotic cell cycle phase transition +relationship: negatively_regulates GO:0044771 ! meiotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:15:03Z + +[Term] +id: GO:1901995 +name: positive regulation of meiotic cell cycle phase transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition." [GOC:mtg_cell_cycle, GOC:TermGenie, PMID:22841721] +synonym: "activation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "activation of meiotic cell cycle phase transition" NARROW [GOC:TermGenie] +synonym: "positive regulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "up regulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "up regulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "up-regulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle transition" BROAD [GOC:TermGenie] +synonym: "upregulation of meiotic cell cycle phase transition" EXACT [GOC:TermGenie] +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:1901989 ! positive regulation of cell cycle phase transition +is_a: GO:1901993 ! regulation of meiotic cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044771 ! meiotic cell cycle phase transition +relationship: positively_regulates GO:0044771 ! meiotic cell cycle phase transition +created_by: jl +creation_date: 2013-03-19T16:15:08Z + +[Term] +id: GO:1901996 +name: regulation of indoleacetic acid biosynthetic process via tryptophan +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan." [GOC:TermGenie, PMID:23377040] +synonym: "regulation of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "regulation of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "regulation of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "regulation of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +is_a: GO:0010600 ! regulation of auxin biosynthetic process +is_a: GO:0090357 ! regulation of tryptophan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009848 ! indoleacetic acid biosynthetic process via tryptophan +relationship: regulates GO:0009848 ! indoleacetic acid biosynthetic process via tryptophan +created_by: tb +creation_date: 2013-03-19T19:14:09Z + +[Term] +id: GO:1901997 +name: negative regulation of indoleacetic acid biosynthetic process via tryptophan +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan." [GOC:TermGenie, PMID:23377040] +synonym: "down regulation of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "down regulation of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "down regulation of indoleacetic acid biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "down regulation of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "down regulation of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of indoleacetic acid biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of indoleacetic acid biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +synonym: "inhibition of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "inhibition of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "inhibition of indoleacetic acid biosynthetic process via tryptophan" NARROW [GOC:TermGenie] +synonym: "inhibition of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "inhibition of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +synonym: "negative regulation of IAA biosynthetic process via tryptophan" EXACT [GOC:TermGenie] +synonym: "negative regulation of indoleacetic acid anabolism via tryptophan" EXACT [GOC:TermGenie] +synonym: "negative regulation of indoleacetic acid formation via tryptophan" EXACT [GOC:TermGenie] +synonym: "negative regulation of indoleacetic acid synthesis via tryptophan" EXACT [GOC:TermGenie] +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0090356 ! negative regulation of auxin metabolic process +is_a: GO:1901996 ! regulation of indoleacetic acid biosynthetic process via tryptophan +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009848 ! indoleacetic acid biosynthetic process via tryptophan +relationship: negatively_regulates GO:0009848 ! indoleacetic acid biosynthetic process via tryptophan +created_by: tb +creation_date: 2013-03-19T19:14:13Z + +[Term] +id: GO:1901998 +name: toxin transport +namespace: biological_process +def: "The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:TermGenie, PMID:17118486] +is_a: GO:0006810 ! transport +created_by: dph +creation_date: 2013-03-19T19:24:55Z + +[Term] +id: GO:1901999 +name: homogentisate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving homogentisate." [GOC:TermGenie, PMID:22980205] +synonym: "homogentisate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +created_by: tb +creation_date: 2013-03-21T00:01:02Z + +[Term] +id: GO:1902000 +name: homogentisate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of homogentisate." [GOC:TermGenie, PMID:22980205] +synonym: "homogentisate breakdown" EXACT [GOC:TermGenie] +synonym: "homogentisate catabolism" EXACT [GOC:TermGenie] +synonym: "homogentisate degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901999 ! homogentisate metabolic process +created_by: tb +creation_date: 2013-03-21T00:01:12Z + +[Term] +id: GO:1902001 +name: fatty acid transmembrane transport +namespace: biological_process +def: "The process in which a fatty acid is transported across a membrane." [GOC:rb, GOC:TermGenie, PMID:9395310] +is_a: GO:0015908 ! fatty acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: pr +creation_date: 2013-03-21T09:57:00Z + +[Term] +id: GO:1902002 +name: obsolete protein phosphorylation involved in cellular protein catabolic process +namespace: biological_process +def: "OBSOLETE. Any protein phosphorylation that is involved in cellular protein catabolic process." [GOC:rb, GOC:TermGenie, PMID:21098119, PMID:21993622, PMID:23264631] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "protein amino acid phosphorylation involved in cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "protein amino acid phosphorylation involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "protein amino acid phosphorylation involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "protein amino acid phosphorylation involved in cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "protein phosphorylation involved in cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "protein phosphorylation involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "protein phosphorylation involved in cellular protein degradation" EXACT [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14137 xsd:anyURI +is_obsolete: true +created_by: pr +creation_date: 2013-03-21T10:08:19Z + +[Term] +id: GO:1902003 +name: regulation of amyloid-beta formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amyloid-beta formation." [GOC:dph, GOC:TermGenie, PMID:17098871] +synonym: "regulation of beta-amyloid formation" EXACT [] +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034205 ! amyloid-beta formation +relationship: regulates GO:0034205 ! amyloid-beta formation +created_by: dph +creation_date: 2013-03-21T19:59:26Z + +[Term] +id: GO:1902004 +name: positive regulation of amyloid-beta formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amyloid-beta formation." [GOC:dph, GOC:TermGenie, PMID:17098871] +synonym: "activation of beta-amyloid formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-amyloid formation" EXACT [] +synonym: "up regulation of beta-amyloid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-amyloid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-amyloid formation" EXACT [GOC:TermGenie] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:1902003 ! regulation of amyloid-beta formation +is_a: GO:1902993 ! positive regulation of amyloid precursor protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034205 ! amyloid-beta formation +relationship: positively_regulates GO:0034205 ! amyloid-beta formation +created_by: dph +creation_date: 2013-03-21T19:59:31Z + +[Term] +id: GO:1902005 +name: regulation of proline biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proline biosynthetic process." [GOC:TermGenie, PMID:23415322] +synonym: "regulation of proline anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of proline formation" EXACT [GOC:TermGenie] +synonym: "regulation of proline synthesis" EXACT [GOC:TermGenie] +is_a: GO:2000214 ! regulation of proline metabolic process +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006561 ! proline biosynthetic process +relationship: regulates GO:0006561 ! proline biosynthetic process +created_by: tb +creation_date: 2013-03-21T21:48:07Z + +[Term] +id: GO:1902006 +name: negative regulation of proline biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process." [GOC:TermGenie, PMID:23415322] +synonym: "down regulation of proline anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of proline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of proline formation" EXACT [GOC:TermGenie] +synonym: "down regulation of proline synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of proline anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of proline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of proline formation" EXACT [GOC:TermGenie] +synonym: "downregulation of proline synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of proline anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of proline biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of proline formation" EXACT [GOC:TermGenie] +synonym: "inhibition of proline synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of proline anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of proline biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of proline formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of proline synthesis" EXACT [GOC:TermGenie] +is_a: GO:1902005 ! regulation of proline biosynthetic process +is_a: GO:2000215 ! negative regulation of proline metabolic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006561 ! proline biosynthetic process +relationship: negatively_regulates GO:0006561 ! proline biosynthetic process +created_by: tb +creation_date: 2013-03-21T21:48:12Z + +[Term] +id: GO:1902007 +name: regulation of toxin transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of toxin transport." [GOC:dph, GOC:TermGenie, PMID:22792315] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901998 ! toxin transport +relationship: regulates GO:1901998 ! toxin transport +created_by: dph +creation_date: 2013-03-22T12:53:56Z + +[Term] +id: GO:1902008 +name: negative regulation of toxin transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport." [GOC:dph, GOC:TermGenie, PMID:22792315] +synonym: "down regulation of toxin transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of toxin transport" EXACT [GOC:TermGenie] +synonym: "downregulation of toxin transport" EXACT [GOC:TermGenie] +synonym: "inhibition of toxin transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1902007 ! regulation of toxin transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901998 ! toxin transport +relationship: negatively_regulates GO:1901998 ! toxin transport +created_by: dph +creation_date: 2013-03-22T12:54:00Z + +[Term] +id: GO:1902009 +name: positive regulation of toxin transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of toxin transport." [GOC:dph, GOC:TermGenie, PMID:22792315] +synonym: "activation of toxin transport" NARROW [GOC:TermGenie] +synonym: "up regulation of toxin transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of toxin transport" EXACT [GOC:TermGenie] +synonym: "upregulation of toxin transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1902007 ! regulation of toxin transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901998 ! toxin transport +relationship: positively_regulates GO:1901998 ! toxin transport +created_by: dph +creation_date: 2013-03-22T12:54:09Z + +[Term] +id: GO:1902010 +name: negative regulation of translation in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." [GOC:dph, GOC:TermGenie, PMID:10882126] +synonym: "down regulation of protein biosynthetic process involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down regulation of protein biosynthetic process involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein biosynthetic process involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein biosynthetic process involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "downregulation of protein biosynthetic process involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of protein biosynthetic process involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "inhibition of protein biosynthetic process involved in ER stress response" NARROW [GOC:TermGenie] +synonym: "inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "inhibition of protein biosynthetic process involved in response to ER stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein anabolism involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein anabolism involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein anabolism involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthesis involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthesis involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthetic process involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein biosynthetic process involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein formation involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein formation involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein formation involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein synthesis involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein synthesis involved in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein synthesis involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of translation involved in ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of translation involved in response to ER stress" EXACT [GOC:TermGenie] +synonym: "protein biosynthesis inhibitor activity involved in ER stress response" RELATED [GOC:TermGenie] +synonym: "protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "protein biosynthesis inhibitor activity involved in response to ER stress" RELATED [GOC:TermGenie] +synonym: "protein biosynthetic process inhibitor activity involved in ER stress response" RELATED [GOC:TermGenie] +synonym: "protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "protein biosynthetic process inhibitor activity involved in response to ER stress" RELATED [GOC:TermGenie] +is_a: GO:0032055 ! negative regulation of translation in response to stress +is_a: GO:0036490 ! regulation of translation in response to endoplasmic reticulum stress +created_by: dph +creation_date: 2013-03-22T13:43:26Z + +[Term] +id: GO:1902011 +name: poly(ribitol phosphate) teichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid." [GOC:TermGenie, PMID:11882717, UniPathway:UPA00790] +synonym: "poly(ribitol phosphate) teichoic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046374 ! teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:36Z + +[Term] +id: GO:1902012 +name: poly(ribitol phosphate) teichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid." [GOC:TermGenie, PMID:11882717, UniPathway:UPA00790] +synonym: "poly(ribitol phosphate) teichoic acid anabolism" EXACT [GOC:TermGenie] +synonym: "poly(ribitol phosphate) teichoic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(ribitol phosphate) teichoic acid formation" EXACT [GOC:TermGenie] +synonym: "poly(ribitol phosphate) teichoic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019350 ! teichoic acid biosynthetic process +is_a: GO:1902011 ! poly(ribitol phosphate) teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:40Z + +[Term] +id: GO:1902013 +name: poly(glycerol phosphate) teichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid." [GOC:TermGenie, PMID:11882717, UniPathway:UPA00827] +synonym: "poly(glycerol phosphate) teichoic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046374 ! teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:45Z + +[Term] +id: GO:1902014 +name: poly(glycerol phosphate) teichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid." [GOC:TermGenie, PMID:11882717, UniPathway:UPA00827] +synonym: "poly(glycerol phosphate) teichoic acid anabolism" EXACT [GOC:TermGenie] +synonym: "poly(glycerol phosphate) teichoic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(glycerol phosphate) teichoic acid formation" EXACT [GOC:TermGenie] +synonym: "poly(glycerol phosphate) teichoic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019350 ! teichoic acid biosynthetic process +is_a: GO:1902013 ! poly(glycerol phosphate) teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:50Z + +[Term] +id: GO:1902015 +name: poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid." [GOC:TermGenie, PMID:16735734, UniPathway:UPA00789, UniPathway:UPA00828] +synonym: "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism" EXACT [GOC:TermGenie] +synonym: "poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process" EXACT [] +synonym: "poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism" EXACT [] +is_a: GO:0046374 ! teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:55Z + +[Term] +id: GO:1902016 +name: poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid." [GOC:TermGenie, PMID:16735734, UniPathway:UPA00789, UniPathway:UPA00828] +synonym: "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid anabolism" EXACT [GOC:TermGenie] +synonym: "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid formation" EXACT [GOC:TermGenie] +synonym: "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid synthesis" EXACT [GOC:TermGenie] +synonym: "poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis" EXACT [] +synonym: "poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process" EXACT [] +is_a: GO:0019350 ! teichoic acid biosynthetic process +is_a: GO:1902015 ! poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process +created_by: tb +creation_date: 2013-03-22T15:43:59Z + +[Term] +id: GO:1902017 +name: regulation of cilium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] +synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of cilium biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060271 ! cilium assembly +relationship: regulates GO:0060271 ! cilium assembly +created_by: dph +creation_date: 2013-03-26T18:10:51Z + +[Term] +id: GO:1902018 +name: negative regulation of cilium assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] +synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cilium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cilium biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:1902017 ! regulation of cilium assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060271 ! cilium assembly +relationship: negatively_regulates GO:0060271 ! cilium assembly +created_by: dph +creation_date: 2013-03-26T18:10:56Z + +[Term] +id: GO:1902019 +name: regulation of cilium-dependent cell motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] +synonym: "regulation of ciliary cell motility" RELATED [] +synonym: "regulation of cilium cell motility" EXACT [] +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060285 ! cilium-dependent cell motility +relationship: regulates GO:0060285 ! cilium-dependent cell motility +created_by: jl +creation_date: 2013-03-27T14:42:38Z + +[Term] +id: GO:1902020 +name: negative regulation of cilium-dependent cell motility +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] +synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie] +synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie] +synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie] +synonym: "inhibition of ciliary cell motility" NARROW [GOC:TermGenie] +synonym: "negative regulation of ciliary cell motility" RELATED [] +synonym: "negative regulation of cilium cell motility" EXACT [] +is_a: GO:1902019 ! regulation of cilium-dependent cell motility +is_a: GO:2000146 ! negative regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060285 ! cilium-dependent cell motility +relationship: negatively_regulates GO:0060285 ! cilium-dependent cell motility +created_by: jl +creation_date: 2013-03-27T14:42:42Z + +[Term] +id: GO:1902021 +name: regulation of bacterial-type flagellum-dependent cell motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] +synonym: "regulation of bacterial-type flagellar cell motility" RELATED [] +synonym: "regulation of bacterial-type flagellum cell motility" EXACT [] +synonym: "regulation of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071973 ! bacterial-type flagellum-dependent cell motility +relationship: regulates GO:0071973 ! bacterial-type flagellum-dependent cell motility +created_by: jl +creation_date: 2013-03-27T14:42:50Z + +[Term] +id: GO:1902022 +name: L-lysine transport +namespace: biological_process +def: "The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0006812 ! cation transport +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0015893 ! drug transport +created_by: kmv +creation_date: 2013-03-27T16:09:06Z + +[Term] +id: GO:1902023 +name: L-arginine transport +namespace: biological_process +alt_id: GO:0043091 +def: "The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:kmv, GOC:TermGenie, PMID:22822152] +synonym: "L-arginine import" NARROW [] +synonym: "L-arginine uptake" NARROW [] +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0015809 ! arginine transport +is_a: GO:0015893 ! drug transport +created_by: kmv +creation_date: 2013-03-27T16:09:11Z + +[Term] +id: GO:1902024 +name: L-histidine transport +namespace: biological_process +def: "The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0015807 ! L-amino acid transport +is_a: GO:0015817 ! histidine transport +is_a: GO:0015893 ! drug transport +created_by: kmv +creation_date: 2013-03-27T16:09:15Z + +[Term] +id: GO:1902025 +name: nitrate import +namespace: biological_process +def: "The directed movement of nitrate into a cell or organelle." [GOC:TermGenie, PMID:22658680] +synonym: "nitrate influx" EXACT [] +synonym: "nitrate uptake" EXACT [] +is_a: GO:0015706 ! nitrate transport +created_by: tb +creation_date: 2013-03-27T21:32:58Z + +[Term] +id: GO:1902026 +name: regulation of cartilage condensation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cartilage condensation." [GOC:TermGenie, PMID:17202865] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0061035 ! regulation of cartilage development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001502 ! cartilage condensation +relationship: regulates GO:0001502 ! cartilage condensation +created_by: jl +creation_date: 2013-03-28T17:02:42Z + +[Term] +id: GO:1902027 +name: positive regulation of cartilage condensation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cartilage condensation." [GOC:TermGenie, PMID:17202865] +synonym: "activation of cartilage condensation" NARROW [GOC:TermGenie] +synonym: "up regulation of cartilage condensation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cartilage condensation" EXACT [GOC:TermGenie] +synonym: "upregulation of cartilage condensation" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0061036 ! positive regulation of cartilage development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1902026 ! regulation of cartilage condensation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001502 ! cartilage condensation +relationship: positively_regulates GO:0001502 ! cartilage condensation +created_by: jl +creation_date: 2013-03-28T17:02:46Z + +[Term] +id: GO:1902028 +name: regulation of histone H3-K18 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation." [GOC:TermGenie, PMID:22110608] +synonym: "regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043971 ! histone H3-K18 acetylation +relationship: regulates GO:0043971 ! histone H3-K18 acetylation +created_by: jl +creation_date: 2013-03-28T20:17:39Z + +[Term] +id: GO:1902029 +name: positive regulation of histone H3-K18 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation." [GOC:TermGenie, PMID:22110608] +synonym: "activation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "activation of histone H3-K18 acetylation" NARROW [GOC:TermGenie] +synonym: "activation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:1902028 ! regulation of histone H3-K18 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043971 ! histone H3-K18 acetylation +relationship: positively_regulates GO:0043971 ! histone H3-K18 acetylation +created_by: jl +creation_date: 2013-03-28T20:17:44Z + +[Term] +id: GO:1902030 +name: negative regulation of histone H3-K18 acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation." [GOC:TermGenie, PMID:22110608] +synonym: "down regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K18 acetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3-K18 acetylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone H3K18 acetylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone H3 acetylation at K18" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone H3K18 acetylation" EXACT [GOC:TermGenie] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:1902028 ! regulation of histone H3-K18 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043971 ! histone H3-K18 acetylation +relationship: negatively_regulates GO:0043971 ! histone H3-K18 acetylation +created_by: jl +creation_date: 2013-03-28T20:19:39Z + +[Term] +id: GO:1902031 +name: regulation of NADP metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NADP metabolic process." [GOC:TermGenie, PMID:23334421] +synonym: "regulation of NAD phosphorylation and dephosphorylation" RELATED [GOC:TermGenie] +synonym: "regulation of NADP (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of NADP (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of NADP (reduced) metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of NADP (reduced) metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of NADP metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of NADPH metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of NADPH metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of nicotinamide adenine dinucleotide phosphate metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized NADP metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized NADP metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of reduced NADP metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of reduced NADP metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of reduced nicotinamide adenine dinucleotide phosphate metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of reduced nicotinamide adenine dinucleotide phosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006739 ! NADP metabolic process +relationship: regulates GO:0006739 ! NADP metabolic process +created_by: jl +creation_date: 2013-03-28T20:21:48Z + +[Term] +id: GO:1902032 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress +namespace: biological_process +def: "OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in response to osmotic stress." [GOC:kmv, GOC:TermGenie, PMID:18636113] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "global transcription regulation from Pol II promoter involved in osmotic response" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in osmotic stress response" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in response to osmotic stress" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic response" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic stress response" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in response to osmotic stress" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in osmotic response" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in osmotic stress response" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in response to osmotic stress" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in osmotic response" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in osmotic stress response" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in osmotic response" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in osmotic stress response" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress" EXACT [] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in osmotic response" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in osmotic stress response" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in response to osmotic stress" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: kmv +creation_date: 2013-04-01T17:24:04Z + +[Term] +id: GO:1902033 +name: regulation of hematopoietic stem cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] +synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0072091 ! regulation of stem cell proliferation +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071425 ! hematopoietic stem cell proliferation +relationship: regulates GO:0071425 ! hematopoietic stem cell proliferation +created_by: ss +creation_date: 2013-04-02T05:13:19Z + +[Term] +id: GO:1902034 +name: negative regulation of hematopoietic stem cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] +synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation +is_a: GO:1903707 ! negative regulation of hemopoiesis +is_a: GO:2000647 ! negative regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation +relationship: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation +created_by: ss +creation_date: 2013-04-02T05:13:24Z + +[Term] +id: GO:1902035 +name: positive regulation of hematopoietic stem cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] +synonym: "activation of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation +is_a: GO:1903708 ! positive regulation of hemopoiesis +is_a: GO:2000648 ! positive regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation +relationship: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation +created_by: ss +creation_date: 2013-04-02T05:13:31Z + +[Term] +id: GO:1902036 +name: regulation of hematopoietic stem cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] +synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060218 ! hematopoietic stem cell differentiation +relationship: regulates GO:0060218 ! hematopoietic stem cell differentiation +created_by: ss +creation_date: 2013-04-02T05:19:09Z + +[Term] +id: GO:1902037 +name: negative regulation of hematopoietic stem cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] +synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation +is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation +is_a: GO:2000737 ! negative regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation +relationship: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation +created_by: ss +creation_date: 2013-04-02T05:19:14Z + +[Term] +id: GO:1902038 +name: positive regulation of hematopoietic stem cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] +synonym: "activation of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation +is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation +is_a: GO:2000738 ! positive regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation +relationship: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation +created_by: ss +creation_date: 2013-04-02T05:19:19Z + +[Term] +id: GO:1902039 +name: negative regulation of seed dormancy process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process." [GOC:TermGenie, PMID:23378449] +synonym: "down regulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "down regulation of seed dormancy process" EXACT [GOC:TermGenie] +synonym: "down-regulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "down-regulation of seed dormancy process" EXACT [GOC:TermGenie] +synonym: "downregulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "downregulation of seed dormancy process" EXACT [GOC:TermGenie] +synonym: "inhibition of seed dormancy" RELATED [GOC:TermGenie] +synonym: "inhibition of seed dormancy process" NARROW [GOC:TermGenie] +synonym: "negative regulation of seed dormancy" RELATED [GOC:TermGenie] +is_a: GO:2000033 ! regulation of seed dormancy process +is_a: GO:2000692 ! negative regulation of seed maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010162 ! seed dormancy process +relationship: negatively_regulates GO:0010162 ! seed dormancy process +created_by: tb +creation_date: 2013-04-02T22:13:15Z + +[Term] +id: GO:1902040 +name: positive regulation of seed dormancy process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of seed dormancy process." [GOC:TermGenie, PMID:23378449] +synonym: "activation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "activation of seed dormancy process" NARROW [GOC:TermGenie] +synonym: "positive regulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "up regulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "up regulation of seed dormancy process" EXACT [GOC:TermGenie] +synonym: "up-regulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "up-regulation of seed dormancy process" EXACT [GOC:TermGenie] +synonym: "upregulation of seed dormancy" RELATED [GOC:TermGenie] +synonym: "upregulation of seed dormancy process" EXACT [GOC:TermGenie] +is_a: GO:2000033 ! regulation of seed dormancy process +is_a: GO:2000693 ! positive regulation of seed maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010162 ! seed dormancy process +relationship: positively_regulates GO:0010162 ! seed dormancy process +created_by: tb +creation_date: 2013-04-02T22:13:20Z + +[Term] +id: GO:1902041 +name: regulation of extrinsic apoptotic signaling pathway via death domain receptors +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors." [GOC:TermGenie, PMID:17245429] +synonym: "regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +is_a: GO:2001236 ! regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +relationship: regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +created_by: lb +creation_date: 2013-04-03T07:16:59Z + +[Term] +id: GO:1902042 +name: negative regulation of extrinsic apoptotic signaling pathway via death domain receptors +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors." [GOC:TermGenie, PMID:17245429] +synonym: "down regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +synonym: "down-regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +synonym: "downregulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +synonym: "inhibition of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of extrinsic apoptotic signaling pathway via death domain receptors" NARROW [GOC:TermGenie] +synonym: "negative regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1902041 ! regulation of extrinsic apoptotic signaling pathway via death domain receptors +is_a: GO:2001237 ! negative regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +relationship: negatively_regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +created_by: lb +creation_date: 2013-04-03T07:17:04Z + +[Term] +id: GO:1902043 +name: positive regulation of extrinsic apoptotic signaling pathway via death domain receptors +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors." [GOC:TermGenie, PMID:17245429] +synonym: "activation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of extrinsic apoptotic signaling pathway via death domain receptors" NARROW [GOC:TermGenie] +synonym: "positive regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +synonym: "up-regulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +synonym: "upregulation of death receptor-mediated apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of extrinsic apoptotic signaling pathway via death domain receptors" EXACT [GOC:TermGenie] +is_a: GO:1902041 ! regulation of extrinsic apoptotic signaling pathway via death domain receptors +is_a: GO:2001238 ! positive regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +relationship: positively_regulates GO:0008625 ! extrinsic apoptotic signaling pathway via death domain receptors +created_by: lb +creation_date: 2013-04-03T07:17:11Z + +[Term] +id: GO:1902044 +name: regulation of Fas signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Fas signaling pathway." [GOC:TermGenie, PMID:17245429] +synonym: "regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036337 ! Fas signaling pathway +relationship: regulates GO:0036337 ! Fas signaling pathway +created_by: lb +creation_date: 2013-04-03T07:21:23Z + +[Term] +id: GO:1902045 +name: negative regulation of Fas signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway." [GOC:TermGenie, PMID:17245429] +synonym: "down regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of Apo-1 signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of CD95 signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of Fas receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of FasR signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902044 ! regulation of Fas signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036337 ! Fas signaling pathway +relationship: negatively_regulates GO:0036337 ! Fas signaling pathway +created_by: lb +creation_date: 2013-04-03T07:21:28Z + +[Term] +id: GO:1902046 +name: positive regulation of Fas signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Fas signaling pathway." [GOC:TermGenie, PMID:17245429] +synonym: "activation of Apo-1 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of CD95 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of Fas receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of FasR signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of FasR signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Apo-1 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of CD95 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of FAS ligand-Fas signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of Fas receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Fas signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Fas-FasL signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of FasL signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of FasR signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902044 ! regulation of Fas signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036337 ! Fas signaling pathway +relationship: positively_regulates GO:0036337 ! Fas signaling pathway +created_by: lb +creation_date: 2013-04-03T07:21:33Z + +[Term] +id: GO:1902047 +name: polyamine transmembrane transport +namespace: biological_process +alt_id: GO:1905122 +def: "The process in which a polyamine macromolecule is transported across a membrane." [GOC:TermGenie, GOC:vw] +synonym: "polyamine import" RELATED [] +synonym: "polyamine uptake" RELATED [PMID:23205587] +is_a: GO:0015846 ! polyamine transport +is_a: GO:0055085 ! transmembrane transport +created_by: tb +creation_date: 2013-04-03T15:34:57Z + +[Term] +id: GO:1902048 +name: neosartoricin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving neosartoricin." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "neosartoricin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0030638 ! polyketide metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1900619 ! acetate ester metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: di +creation_date: 2013-04-08T20:31:02Z + +[Term] +id: GO:1902049 +name: neosartoricin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of neosartoricin." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "neosartoricin breakdown" EXACT [GOC:TermGenie] +synonym: "neosartoricin catabolism" EXACT [GOC:TermGenie] +synonym: "neosartoricin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0030640 ! polyketide catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1902048 ! neosartoricin metabolic process +created_by: di +creation_date: 2013-04-08T20:31:06Z + +[Term] +id: GO:1902050 +name: neosartoricin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of neosartoricin." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "neosartoricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030639 ! polyketide biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1900620 ! acetate ester biosynthetic process +is_a: GO:1902048 ! neosartoricin metabolic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process +created_by: di +creation_date: 2013-04-08T20:31:11Z + +[Term] +id: GO:1902051 +name: (25S)-Delta(4)-dafachronate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with (25S)-Delta(4)-dafachronate." [GOC:TermGenie, PMID:16529801] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:1990239 ! steroid hormone binding +created_by: ab +creation_date: 2013-04-11T08:33:41Z + +[Term] +id: GO:1902052 +name: (25S)-Delta(7)-dafachronate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with (25S)-Delta(7)-dafachronate." [GOC:TermGenie, PMID:16529801] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:1990239 ! steroid hormone binding +created_by: ab +creation_date: 2013-04-11T08:34:38Z + +[Term] +id: GO:1902053 +name: regulation of neosartoricin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900732 ! regulation of polyketide biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902050 ! neosartoricin biosynthetic process +relationship: regulates GO:1902050 ! neosartoricin biosynthetic process +created_by: di +creation_date: 2013-04-11T15:46:06Z + +[Term] +id: GO:1902054 +name: negative regulation of neosartoricin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "down regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of neosartoricin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900733 ! negative regulation of polyketide biosynthetic process +is_a: GO:1902053 ! regulation of neosartoricin biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902050 ! neosartoricin biosynthetic process +relationship: negatively_regulates GO:1902050 ! neosartoricin biosynthetic process +created_by: di +creation_date: 2013-04-11T15:46:15Z + +[Term] +id: GO:1902055 +name: positive regulation of neosartoricin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23368997] +synonym: "activation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of neosartoricin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "activation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of neosartoricin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of neosartoricin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of neosartoricin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of neosartoricin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of neosartoricin synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900734 ! positive regulation of polyketide biosynthetic process +is_a: GO:1902053 ! regulation of neosartoricin biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902050 ! neosartoricin biosynthetic process +relationship: positively_regulates GO:1902050 ! neosartoricin biosynthetic process +created_by: di +creation_date: 2013-04-11T15:46:20Z + +[Term] +id: GO:1902056 +name: (25S)-Delta(7)-dafachronate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate." [GOC:TermGenie, PMID:22505847] +synonym: "(25S)-Delta(7)-dafachronate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042445 ! hormone metabolic process +created_by: ab +creation_date: 2013-04-13T09:05:27Z + +[Term] +id: GO:1902057 +name: (25S)-Delta(4)-dafachronate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate." [GOC:TermGenie, PMID:20178781] +synonym: "(25S)-Delta(4)-dafachronate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0042445 ! hormone metabolic process +created_by: ab +creation_date: 2013-04-13T09:22:54Z + +[Term] +id: GO:1902058 +name: regulation of sporocarp development involved in sexual reproduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction." [GOC:di, GOC:TermGenie, PMID:23480775] +synonym: "regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +is_a: GO:0031155 ! regulation of reproductive fruiting body development +is_a: GO:0043900 ! regulation of multi-organism process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000909 ! sporocarp development involved in sexual reproduction +relationship: regulates GO:0000909 ! sporocarp development involved in sexual reproduction +created_by: di +creation_date: 2013-04-16T04:08:38Z + +[Term] +id: GO:1902059 +name: negative regulation of sporocarp development involved in sexual reproduction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction." [GOC:di, GOC:TermGenie, PMID:23480775] +synonym: "down regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "down regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "down regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "down regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "down regulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "down-regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "down-regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "down-regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "down-regulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +synonym: "downregulation of ascus development" NARROW [GOC:TermGenie] +synonym: "downregulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "downregulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "downregulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "downregulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +synonym: "inhibition of ascus development" NARROW [GOC:TermGenie] +synonym: "inhibition of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "inhibition of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "inhibition of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "inhibition of sporocarp development involved in sexual reproduction" NARROW [GOC:TermGenie] +synonym: "negative regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "negative regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "negative regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "negative regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0075262 ! negative regulation of spore-bearing organ development +is_a: GO:1902058 ! regulation of sporocarp development involved in sexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000909 ! sporocarp development involved in sexual reproduction +relationship: negatively_regulates GO:0000909 ! sporocarp development involved in sexual reproduction +created_by: di +creation_date: 2013-04-16T04:08:42Z + +[Term] +id: GO:1902060 +name: positive regulation of sporocarp development involved in sexual reproduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction." [GOC:di, GOC:TermGenie, PMID:23480775] +synonym: "activation of ascus development" NARROW [GOC:TermGenie] +synonym: "activation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "activation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "activation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "activation of sporocarp development involved in sexual reproduction" NARROW [GOC:TermGenie] +synonym: "positive regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "positive regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "positive regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "positive regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "up regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "up regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "up regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "up regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "up regulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of ascus development" NARROW [GOC:TermGenie] +synonym: "up-regulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "up-regulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "up-regulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "up-regulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +synonym: "upregulation of ascus development" NARROW [GOC:TermGenie] +synonym: "upregulation of fruiting body development involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "upregulation of fruiting body formation involved in sexual reproduction" BROAD [GOC:TermGenie] +synonym: "upregulation of perfect stage fruiting body development" NARROW [GOC:TermGenie] +synonym: "upregulation of sporocarp development involved in sexual reproduction" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0075261 ! positive regulation of spore-bearing organ development +is_a: GO:1902058 ! regulation of sporocarp development involved in sexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000909 ! sporocarp development involved in sexual reproduction +relationship: positively_regulates GO:0000909 ! sporocarp development involved in sexual reproduction +created_by: di +creation_date: 2013-04-16T04:08:47Z + +[Term] +id: GO:1902061 +name: betaine aldehyde metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving betaine aldehyde." [GOC:di, GOC:TermGenie, PMID:23563483] +synonym: "betaine aldehyde metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006807 ! nitrogen compound metabolic process +is_a: GO:0071704 ! organic substance metabolic process +created_by: di +creation_date: 2013-04-16T12:07:03Z + +[Term] +id: GO:1902062 +name: betaine aldehyde catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of betaine aldehyde." [GOC:di, GOC:TermGenie, PMID:23563483] +synonym: "betaine aldehyde breakdown" EXACT [GOC:TermGenie] +synonym: "betaine aldehyde catabolism" EXACT [GOC:TermGenie] +synonym: "betaine aldehyde degradation" EXACT [GOC:TermGenie] +is_a: GO:1901575 ! organic substance catabolic process +is_a: GO:1902061 ! betaine aldehyde metabolic process +created_by: di +creation_date: 2013-04-16T12:07:12Z + +[Term] +id: GO:1902063 +name: betaine aldehyde biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of betaine aldehyde." [GOC:di, GOC:TermGenie, PMID:23563483] +synonym: "betaine aldehyde anabolism" EXACT [GOC:TermGenie] +synonym: "betaine aldehyde biosynthesis" EXACT [GOC:TermGenie] +synonym: "betaine aldehyde formation" EXACT [GOC:TermGenie] +synonym: "betaine aldehyde synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901576 ! organic substance biosynthetic process +is_a: GO:1902061 ! betaine aldehyde metabolic process +created_by: di +creation_date: 2013-04-16T12:07:17Z + +[Term] +id: GO:1902064 +name: regulation of transcription from RNA polymerase II promoter involved in spermatogenesis +namespace: biological_process +def: "Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis." [GOC:kmv, GOC:TermGenie, PMID:22570621] +synonym: "global transcription regulation from Pol II promoter involved in generation of spermatozoa" RELATED [GOC:TermGenie] +synonym: "global transcription regulation from Pol II promoter involved in spermatogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa" RELATED [GOC:TermGenie] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in generation of spermatozoa" RELATED [GOC:TermGenie] +synonym: "regulation of global transcription from Pol II promoter involved in spermatogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in generation of spermatozoa" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from Pol II promoter involved in spermatogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa" RELATED [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis" RELATED [GOC:TermGenie] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0007283 ! spermatogenesis +relationship: part_of GO:0007283 ! spermatogenesis +created_by: kmv +creation_date: 2013-04-16T20:27:18Z + +[Term] +id: GO:1902065 +name: response to L-glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus." [GOC:TermGenie, PMID:23574009] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +created_by: tb +creation_date: 2013-04-16T21:21:14Z + +[Term] +id: GO:1902066 +name: regulation of cell wall pectin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process." [GOC:TermGenie, PMID:23453954] +synonym: "regulation of cell wall pectin metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of cellulose and pectin-containing cell wall pectin metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of pectin metabolism during cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of plant-type cell wall pectin metabolic process" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052546 ! cell wall pectin metabolic process +relationship: regulates GO:0052546 ! cell wall pectin metabolic process +created_by: tb +creation_date: 2013-04-17T20:05:56Z + +[Term] +id: GO:1902068 +name: regulation of sphingolipid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sphingolipid signaling." [GOC:TermGenie, PMID:20870412] +synonym: "regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090520 ! sphingolipid mediated signaling pathway +relationship: regulates GO:0090520 ! sphingolipid mediated signaling pathway +created_by: bf +creation_date: 2013-04-18T13:24:47Z + +[Term] +id: GO:1902069 +name: negative regulation of sphingolipid mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling." [GOC:TermGenie, PMID:20870412] +synonym: "down regulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of sphingolipid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902068 ! regulation of sphingolipid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090520 ! sphingolipid mediated signaling pathway +relationship: negatively_regulates GO:0090520 ! sphingolipid mediated signaling pathway +created_by: bf +creation_date: 2013-04-18T13:24:51Z + +[Term] +id: GO:1902070 +name: positive regulation of sphingolipid mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sphingolipid signaling." [GOC:TermGenie, PMID:20870412] +synonym: "activation of sphingolipid mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of sphingolipid mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of sphingolipid signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902068 ! regulation of sphingolipid mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090520 ! sphingolipid mediated signaling pathway +relationship: positively_regulates GO:0090520 ! sphingolipid mediated signaling pathway +created_by: bf +creation_date: 2013-04-18T13:24:56Z + +[Term] +id: GO:1902071 +name: regulation of hypoxia-inducible factor-1alpha signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway." [GOC:bf, GOC:TermGenie] +synonym: "regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:1900037 ! regulation of cellular response to hypoxia +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +relationship: regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +created_by: bf +creation_date: 2013-04-18T13:28:21Z + +[Term] +id: GO:1902072 +name: negative regulation of hypoxia-inducible factor-1alpha signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway." [GOC:bf, GOC:TermGenie] +synonym: "down regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of hypoxia-inducible factor-1alpha signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900038 ! negative regulation of cellular response to hypoxia +is_a: GO:1902071 ! regulation of hypoxia-inducible factor-1alpha signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +relationship: negatively_regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +created_by: bf +creation_date: 2013-04-18T13:28:25Z + +[Term] +id: GO:1902073 +name: positive regulation of hypoxia-inducible factor-1alpha signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway." [GOC:bf, GOC:TermGenie, PMID:21685248] +synonym: "activation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "activation of hypoxia-inducible factor-1alpha signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "hypoxic stabilization of HIF1A" NARROW [] +synonym: "positive regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of HIF1alpha pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of hypoxia-inducible factor-1alpha signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of hypoxia-inducible factor-1alpha signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900039 ! positive regulation of cellular response to hypoxia +is_a: GO:1902071 ! regulation of hypoxia-inducible factor-1alpha signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +relationship: positively_regulates GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway +created_by: bf +creation_date: 2013-04-18T13:28:30Z + +[Term] +id: GO:1902074 +name: response to salt +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] +synonym: "response to salinity" NARROW [GOC:mls] +is_a: GO:0042221 ! response to chemical +created_by: mls +creation_date: 2013-04-22T15:41:57Z + +[Term] +id: GO:1902075 +name: cellular response to salt +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] +synonym: "cellular response to salinity" NARROW [GOC:mls] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1902074 ! response to salt +created_by: mls +creation_date: 2013-04-22T15:42:02Z + +[Term] +id: GO:1902076 +name: regulation of lateral motor column neuron migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lateral motor column neuron migration." [GOC:TermGenie, GOC:yaf, PMID:20711475] +is_a: GO:1905483 ! regulation of motor neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097477 ! lateral motor column neuron migration +relationship: regulates GO:0097477 ! lateral motor column neuron migration +created_by: pr +creation_date: 2013-04-23T14:42:18Z + +[Term] +id: GO:1902077 +name: negative regulation of lateral motor column neuron migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration." [GOC:TermGenie, GOC:yaf, PMID:20711475] +synonym: "down regulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +synonym: "downregulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +synonym: "inhibition of lateral motor column neuron migration" NARROW [GOC:TermGenie] +is_a: GO:1902076 ! regulation of lateral motor column neuron migration +is_a: GO:1905484 ! negative regulation of motor neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097477 ! lateral motor column neuron migration +relationship: negatively_regulates GO:0097477 ! lateral motor column neuron migration +created_by: pr +creation_date: 2013-04-23T14:42:23Z + +[Term] +id: GO:1902078 +name: positive regulation of lateral motor column neuron migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration." [GOC:TermGenie, GOC:yaf, PMID:20711475] +synonym: "activation of lateral motor column neuron migration" NARROW [GOC:TermGenie] +synonym: "up regulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +synonym: "upregulation of lateral motor column neuron migration" EXACT [GOC:TermGenie] +is_a: GO:1902076 ! regulation of lateral motor column neuron migration +is_a: GO:1905485 ! positive regulation of motor neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097477 ! lateral motor column neuron migration +relationship: positively_regulates GO:0097477 ! lateral motor column neuron migration +created_by: pr +creation_date: 2013-04-23T14:42:28Z + +[Term] +id: GO:1902079 +name: D-valine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of D-valine." [GOC:TermGenie, PMID:23085840] +synonym: "D-valine breakdown" EXACT [GOC:TermGenie] +synonym: "D-valine catabolism" EXACT [GOC:TermGenie] +synonym: "D-valine degradation" EXACT [GOC:TermGenie] +is_a: GO:0006574 ! valine catabolic process +is_a: GO:0019478 ! D-amino acid catabolic process +is_a: GO:1902114 ! D-valine metabolic process +created_by: al +creation_date: 2013-04-23T21:34:29Z + +[Term] +id: GO:1902080 +name: regulation of calcium ion import into sarcoplasmic reticulum +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:8349590] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0090279 ! regulation of calcium ion import +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +relationship: regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +created_by: rl +creation_date: 2013-04-24T16:07:50Z + +[Term] +id: GO:1902081 +name: negative regulation of calcium ion import into sarcoplasmic reticulum +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:8349590] +synonym: "down regulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion import into sarcoplasmic reticulum" NARROW [GOC:TermGenie] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0090281 ! negative regulation of calcium ion import +is_a: GO:1902080 ! regulation of calcium ion import into sarcoplasmic reticulum +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +relationship: negatively_regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +created_by: rl +creation_date: 2013-04-24T16:07:59Z + +[Term] +id: GO:1902082 +name: positive regulation of calcium ion import into sarcoplasmic reticulum +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:8349590] +synonym: "activation of calcium ion import into sarcoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion import into sarcoplasmic reticulum" EXACT [GOC:TermGenie] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0090280 ! positive regulation of calcium ion import +is_a: GO:1902080 ! regulation of calcium ion import into sarcoplasmic reticulum +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +relationship: positively_regulates GO:1990036 ! calcium ion import into sarcoplasmic reticulum +created_by: rl +creation_date: 2013-04-24T16:08:03Z + +[Term] +id: GO:1902083 +name: negative regulation of peptidyl-cysteine S-nitrosylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19198614] +synonym: "down regulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "down regulation of S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "downregulation of S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidyl-cysteine S-nitrosylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "inhibition of S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of S-nitrosylation" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:2000169 ! regulation of peptidyl-cysteine S-nitrosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +relationship: negatively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +created_by: rl +creation_date: 2013-04-24T16:49:34Z + +[Term] +id: GO:1902084 +name: fumagillin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fumagillin." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "fumagillin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0019752 ! carboxylic acid metabolic process +is_a: GO:0097176 ! epoxide metabolic process +created_by: di +creation_date: 2013-04-25T14:00:41Z + +[Term] +id: GO:1902085 +name: fumagillin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fumagillin." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "fumagillin breakdown" EXACT [GOC:TermGenie] +synonym: "fumagillin catabolism" EXACT [GOC:TermGenie] +synonym: "fumagillin degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046395 ! carboxylic acid catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1902084 ! fumagillin metabolic process +created_by: di +creation_date: 2013-04-25T14:00:45Z + +[Term] +id: GO:1902086 +name: fumagillin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fumagillin." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "fumagillin formation" EXACT [GOC:TermGenie] +synonym: "fumagillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019748 ! secondary metabolic process +is_a: GO:0046394 ! carboxylic acid biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1902084 ! fumagillin metabolic process +created_by: di +creation_date: 2013-04-25T14:00:50Z + +[Term] +id: GO:1902087 +name: dimethylsulfoniopropionate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin." [GOC:jh2, GOC:TermGenie, PMID:19807777] +synonym: "S,S-dimethyl-beta-propiothetin breakdown" EXACT [GOC:TermGenie] +synonym: "S,S-dimethyl-beta-propiothetin catabolic process" EXACT [] +synonym: "S,S-dimethyl-beta-propiothetin catabolism" EXACT [GOC:TermGenie] +synonym: "S,S-dimethyl-beta-propiothetin degradation" EXACT [GOC:TermGenie] +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901575 ! organic substance catabolic process +created_by: tb +creation_date: 2013-04-26T17:29:13Z + +[Term] +id: GO:1902088 +name: plant-type cell wall loosening involved in abscission +namespace: biological_process +def: "Any plant-type cell wall loosening that is involved in abscission." [GOC:TermGenie, PMID:23479623] +synonym: "cellulose and pectin-containing cell wall loosening involved in abscission" EXACT [GOC:TermGenie] +is_a: GO:0009828 ! plant-type cell wall loosening +is_a: GO:0009830 ! cell wall modification involved in abscission +intersection_of: GO:0009828 ! plant-type cell wall loosening +intersection_of: part_of GO:0009838 ! abscission +created_by: tb +creation_date: 2013-04-26T18:34:45Z + +[Term] +id: GO:1902089 +name: cell wall polysaccharide catabolic process involved in lateral root development +namespace: biological_process +def: "Any cell wall polysaccharide catabolic process that is involved in lateral root development." [GOC:TermGenie, PMID:23479623] +synonym: "cell wall polysaccharide breakdown involved in lateral root development" EXACT [GOC:TermGenie] +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +intersection_of: GO:0044347 ! cell wall polysaccharide catabolic process +intersection_of: part_of GO:0048527 ! lateral root development +relationship: part_of GO:0048527 ! lateral root development +created_by: tb +creation_date: 2013-04-26T18:34:53Z + +[Term] +id: GO:1902090 +name: regulation of fumagillin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043455 ! regulation of secondary metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902086 ! fumagillin biosynthetic process +relationship: regulates GO:1902086 ! fumagillin biosynthetic process +created_by: di +creation_date: 2013-04-27T03:44:59Z + +[Term] +id: GO:1902091 +name: negative regulation of fumagillin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "down regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of fumagillin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "inhibition of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1902090 ! regulation of fumagillin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902086 ! fumagillin biosynthetic process +relationship: negatively_regulates GO:1902086 ! fumagillin biosynthetic process +created_by: di +creation_date: 2013-04-27T03:45:04Z + +[Term] +id: GO:1902092 +name: positive regulation of fumagillin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process." [GOC:di, GOC:TermGenie, PMID:23488861] +synonym: "activation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "activation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "activation of fumagillin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "activation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumagillin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of fumagillin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of fumagillin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of fumagillin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of fumagillin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of fumagillin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1902090 ! regulation of fumagillin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902086 ! fumagillin biosynthetic process +relationship: positively_regulates GO:1902086 ! fumagillin biosynthetic process +created_by: di +creation_date: 2013-04-27T03:45:09Z + +[Term] +id: GO:1902093 +name: positive regulation of flagellated sperm motility +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657] +synonym: "activation of sperm motility" NARROW [GOC:TermGenie] +synonym: "activation of sperm movement" BROAD [GOC:TermGenie] +synonym: "positive regulation of sperm motility" BROAD [] +synonym: "positive regulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "up regulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "up regulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "up-regulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "up-regulation of sperm movement" BROAD [GOC:TermGenie] +synonym: "upregulation of sperm motility" BROAD [GOC:TermGenie] +synonym: "upregulation of sperm movement" BROAD [GOC:TermGenie] +is_a: GO:1901317 ! regulation of flagellated sperm motility +is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030317 ! flagellated sperm motility +relationship: positively_regulates GO:0030317 ! flagellated sperm motility +created_by: bf +creation_date: 2013-04-29T09:15:25Z + +[Term] +id: GO:1902097 +name: positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium." [GOC:kmv, GOC:TermGenie, PMID:17183709] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0050829 ! defense response to Gram-negative bacterium +relationship: part_of GO:0050829 ! defense response to Gram-negative bacterium +created_by: kmv +creation_date: 2013-04-30T16:54:30Z + +[Term] +id: GO:1902098 +name: calcitriol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3." [GOC:TermGenie, PMID:21872797, Wikipedia:Calcitriol_receptor] +synonym: "1,25-dihydroxycholecalciferol binding" EXACT [Wikipedia:Calcitriol] +synonym: "1,25-dihydroxyvitamin D3 binding" EXACT [Wikipedia:Calcitriol] +synonym: "1alpha,25(OH)2 vitamin D3 binding" EXACT [PMID:21872797] +synonym: "1alpha,25(OH)2D3 binding" EXACT [CHEBI:17823] +synonym: "1alpha,25-dihydroxycholecalciferol binding" EXACT [CHEBI:17823] +synonym: "1alpha,25-dihydroxyvitamin D3 binding" EXACT [CHEBI:17823] +synonym: "hormonally active vitamin D3 binding" EXACT [GOC:bf] +is_a: GO:0008144 ! drug binding +is_a: GO:0042562 ! hormone binding +is_a: GO:1902271 ! D3 vitamins binding +created_by: bf +creation_date: 2013-05-02T09:41:15Z + +[Term] +id: GO:1902099 +name: regulation of metaphase/anaphase transition of cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +is_a: GO:0033045 ! regulation of sister chromatid segregation +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +relationship: regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:15Z + +[Term] +id: GO:1902100 +name: negative regulation of metaphase/anaphase transition of cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "down regulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +synonym: "inhibition of metaphase/anaphase transition of cell cycle" NARROW [GOC:TermGenie] +is_a: GO:1901988 ! negative regulation of cell cycle phase transition +is_a: GO:1902099 ! regulation of metaphase/anaphase transition of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +relationship: negatively_regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:20Z + +[Term] +id: GO:1902101 +name: positive regulation of metaphase/anaphase transition of cell cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of metaphase/anaphase transition of cell cycle" NARROW [GOC:TermGenie] +synonym: "up regulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of metaphase/anaphase transition of cell cycle" EXACT [GOC:TermGenie] +is_a: GO:1901989 ! positive regulation of cell cycle phase transition +is_a: GO:1902099 ! regulation of metaphase/anaphase transition of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +relationship: positively_regulates GO:0044784 ! metaphase/anaphase transition of cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:30Z + +[Term] +id: GO:1902102 +name: regulation of metaphase/anaphase transition of meiotic cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1901993 ! regulation of meiotic cell cycle phase transition +is_a: GO:1902099 ! regulation of metaphase/anaphase transition of cell cycle +is_a: GO:1905132 ! regulation of meiotic chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +relationship: regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:38Z + +[Term] +id: GO:1902103 +name: negative regulation of metaphase/anaphase transition of meiotic cell cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "down regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "down regulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "inhibition of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "inhibition of metaphase/anaphase transition of meiotic cell cycle" NARROW [GOC:TermGenie] +synonym: "negative regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1901994 ! negative regulation of meiotic cell cycle phase transition +is_a: GO:1902100 ! negative regulation of metaphase/anaphase transition of cell cycle +is_a: GO:1902102 ! regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905133 ! negative regulation of meiotic chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +relationship: negatively_regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:43Z + +[Term] +id: GO:1902104 +name: positive regulation of metaphase/anaphase transition of meiotic cell cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "activation of metaphase/anaphase transition of meiotic cell cycle" NARROW [GOC:TermGenie] +synonym: "positive regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "up regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "up regulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic metaphase/anaphase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of metaphase/anaphase transition of meiotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:1901995 ! positive regulation of meiotic cell cycle phase transition +is_a: GO:1902101 ! positive regulation of metaphase/anaphase transition of cell cycle +is_a: GO:1902102 ! regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905134 ! positive regulation of meiotic chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +relationship: positively_regulates GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +created_by: jl +creation_date: 2013-05-02T12:45:48Z + +[Term] +id: GO:1902105 +name: regulation of leukocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] +synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002521 ! leukocyte differentiation +relationship: regulates GO:0002521 ! leukocyte differentiation +created_by: pr +creation_date: 2013-05-02T17:32:42Z + +[Term] +id: GO:1902106 +name: negative regulation of leukocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] +synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of immune cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of leucocyte differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of leukocyte differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1902105 ! regulation of leukocyte differentiation +is_a: GO:1903707 ! negative regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002521 ! leukocyte differentiation +relationship: negatively_regulates GO:0002521 ! leukocyte differentiation +created_by: pr +creation_date: 2013-05-02T17:32:47Z + +[Term] +id: GO:1902107 +name: positive regulation of leukocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] +synonym: "activation of immune cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of leucocyte differentiation" NARROW [GOC:TermGenie] +synonym: "activation of leukocyte differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1902105 ! regulation of leukocyte differentiation +is_a: GO:1903708 ! positive regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002521 ! leukocyte differentiation +relationship: positively_regulates GO:0002521 ! leukocyte differentiation +created_by: pr +creation_date: 2013-05-02T17:32:52Z + +[Term] +id: GO:1902108 +name: regulation of mitochondrial membrane permeability involved in apoptotic process +namespace: biological_process +def: "Any regulation of mitochondrial membrane permeability that is involved in apoptotic process." [GOC:mtg_apoptosis, GOC:pm, GOC:TermGenie, PMID:19168129] +synonym: "regulation of mitochondrial membrane permeability involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "regulation of mitochondrial membrane permeability involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "regulation of transport across mitochondrial membrane involved in type I programmed cell death" NARROW [GOC:TermGenie] +is_a: GO:0008637 ! apoptotic mitochondrial changes +is_a: GO:0046902 ! regulation of mitochondrial membrane permeability +intersection_of: GO:0046902 ! regulation of mitochondrial membrane permeability +intersection_of: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2013-05-03T12:09:35Z + +[Term] +id: GO:1902109 +name: negative regulation of mitochondrial membrane permeability involved in apoptotic process +namespace: biological_process +def: "Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process." [GOC:mtg_apoptosis, GOC:pm, GOC:TermGenie, PMID:19168129] +synonym: "mitochondrial membrane impermeability involved in apoptosis" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in apoptotic cell death" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in apoptotic process" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in apoptotic program" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in apoptotic programmed cell death" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in programmed cell death by apoptosis" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeability involved in type I programmed cell death" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in apoptotic cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in apoptotic process" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in programmed cell death by apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane impermeabilization involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial membrane permeability involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of transport across mitochondrial membrane involved in type I programmed cell death" NARROW [GOC:TermGenie] +is_a: GO:0035795 ! negative regulation of mitochondrial membrane permeability +is_a: GO:1902108 ! regulation of mitochondrial membrane permeability involved in apoptotic process +intersection_of: GO:0035795 ! negative regulation of mitochondrial membrane permeability +intersection_of: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2013-05-03T12:11:53Z + +[Term] +id: GO:1902110 +name: positive regulation of mitochondrial membrane permeability involved in apoptotic process +namespace: biological_process +def: "Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process." [GOC:mtg_apoptosis, GOC:pm, GOC:TermGenie, PMID:19168129] +comment: Individual components of the mitochondrial permeability transition pore complex, such as the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D), are involved in this process. +synonym: "mitochondrial membrane permeability transition involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in apoptotic cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in apoptotic process" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in programmed cell death by apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in apoptotic cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in apoptotic process" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in programmed cell death by apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in apoptotic cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in apoptotic process" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in programmed cell death by apoptosis" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in type I programmed cell death" NARROW [GOC:TermGenie] +is_a: GO:1902108 ! regulation of mitochondrial membrane permeability involved in apoptotic process +is_a: GO:1902686 ! mitochondrial outer membrane permeabilization involved in programmed cell death +intersection_of: GO:0035794 ! positive regulation of mitochondrial membrane permeability +intersection_of: part_of GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2013-05-03T12:13:56Z + +[Term] +id: GO:1902111 +name: response to diethyl maleate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus." [GOC:TermGenie, PMID:12100563] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2013-05-08T16:00:35Z + +[Term] +id: GO:1902112 +name: cellular response to diethyl maleate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus." [GOC:TermGenie, PMID:12100563] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902111 ! response to diethyl maleate +created_by: mah +creation_date: 2013-05-08T16:00:40Z + +[Term] +id: GO:1902113 +name: nucleotide phosphorylation involved in DNA repair +namespace: biological_process +def: "Any nucleotide phosphorylation that is involved in DNA repair." [GOC:TermGenie, PMID:11729194] +is_a: GO:0046939 ! nucleotide phosphorylation +intersection_of: GO:0046939 ! nucleotide phosphorylation +intersection_of: part_of GO:0006281 ! DNA repair +relationship: part_of GO:0006281 ! DNA repair +created_by: al +creation_date: 2013-05-13T08:56:02Z + +[Term] +id: GO:1902114 +name: D-valine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving D-valine." [GOC:TermGenie, PMID:23085840] +synonym: "D-valine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006573 ! valine metabolic process +is_a: GO:0046416 ! D-amino acid metabolic process +created_by: al +creation_date: 2013-05-13T23:27:23Z + +[Term] +id: GO:1902115 +name: regulation of organelle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070925 ! organelle assembly +relationship: regulates GO:0070925 ! organelle assembly +created_by: pr +creation_date: 2013-05-14T09:43:21Z + +[Term] +id: GO:1902116 +name: negative regulation of organelle assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] +synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070925 ! organelle assembly +relationship: negatively_regulates GO:0070925 ! organelle assembly +created_by: pr +creation_date: 2013-05-14T09:43:31Z + +[Term] +id: GO:1902117 +name: positive regulation of organelle assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] +synonym: "activation of organelle assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070925 ! organelle assembly +relationship: positively_regulates GO:0070925 ! organelle assembly +created_by: pr +creation_date: 2013-05-14T09:43:36Z + +[Term] +id: GO:1902118 +name: calcidiol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcidiol." [GOC:bf, GOC:TermGenie, PMID:11799400] +synonym: "25(OH)D3 binding" EXACT [CHEBI:17933] +synonym: "25-hydroxycholecalciferol binding" EXACT [CHEBI:17933] +synonym: "25-hydroxyvitamin D3 binding" EXACT [CHEBI:17933] +synonym: "25OHD3 binding" EXACT [PMID:11799400] +synonym: "calcifediol binding" EXACT [CHEBI:17933] +is_a: GO:0008144 ! drug binding +is_a: GO:1902271 ! D3 vitamins binding +created_by: bf +creation_date: 2013-05-15T14:55:58Z + +[Term] +id: GO:1902119 +name: regulation of meiotic spindle elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic spindle elongation." [GOC:TermGenie, PMID:23370392] +synonym: "regulation of spindle elongation during meiosis" EXACT [GOC:TermGenie] +is_a: GO:0032887 ! regulation of spindle elongation +is_a: GO:0040020 ! regulation of meiotic nuclear division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051232 ! meiotic spindle elongation +relationship: regulates GO:0051232 ! meiotic spindle elongation +created_by: al +creation_date: 2013-05-15T15:15:48Z + +[Term] +id: GO:1902120 +name: negative regulation of meiotic spindle elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation." [GOC:TermGenie, PMID:23370392] +synonym: "down regulation of meiotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "down regulation of spindle elongation during meiosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spindle elongation during meiosis" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of spindle elongation during meiosis" EXACT [GOC:TermGenie] +synonym: "inhibition of meiotic spindle elongation" NARROW [GOC:TermGenie] +synonym: "inhibition of spindle elongation during meiosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of spindle elongation during meiosis" EXACT [GOC:TermGenie] +is_a: GO:0045835 ! negative regulation of meiotic nuclear division +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:0051985 ! negative regulation of chromosome segregation +is_a: GO:1902119 ! regulation of meiotic spindle elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051232 ! meiotic spindle elongation +relationship: negatively_regulates GO:0051232 ! meiotic spindle elongation +created_by: al +creation_date: 2013-05-15T15:15:53Z + +[Term] +id: GO:1902121 +name: lithocholic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lithocholic acid." [GOC:bf, GOC:TermGenie, PMID:20371703] +synonym: "LCA binding" EXACT [PMID:20371703] +is_a: GO:0005496 ! steroid binding +is_a: GO:0032052 ! bile acid binding +created_by: bf +creation_date: 2013-05-15T16:05:12Z + +[Term] +id: GO:1902122 +name: chenodeoxycholic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chenodeoxycholic acid." [GOC:bf, GOC:TermGenie, PMID:10334992] +synonym: "CDCA binding" EXACT [CHEBI:16755] +is_a: GO:0005496 ! steroid binding +is_a: GO:0032052 ! bile acid binding +created_by: bf +creation_date: 2013-05-16T09:17:19Z + +[Term] +id: GO:1902123 +name: (-)-pinoresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(-)-pinoresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-pinoresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-pinoresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1901598 ! (-)-pinoresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:05Z + +[Term] +id: GO:1902124 +name: (+)-pinoresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-pinoresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-pinoresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0042445 ! hormone metabolic process +is_a: GO:0042537 ! benzene-containing compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:10Z + +[Term] +id: GO:1902125 +name: (+)-pinoresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-pinoresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(+)-pinoresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(+)-pinoresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1902124 ! (+)-pinoresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:23Z + +[Term] +id: GO:1902126 +name: (+)-pinoresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-pinoresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-pinoresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-pinoresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-pinoresinol formation" EXACT [GOC:TermGenie] +synonym: "(+)-pinoresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1902124 ! (+)-pinoresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:28Z + +[Term] +id: GO:1902127 +name: (-)-lariciresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-lariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(-)-lariciresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:33Z + +[Term] +id: GO:1902128 +name: (-)-lariciresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(-)-lariciresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-lariciresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-lariciresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1902127 ! (-)-lariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:38Z + +[Term] +id: GO:1902129 +name: (-)-lariciresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-lariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(-)-lariciresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-lariciresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-lariciresinol formation" EXACT [GOC:TermGenie] +synonym: "(-)-lariciresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1902127 ! (-)-lariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:44Z + +[Term] +id: GO:1902130 +name: (+)-lariciresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-lariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-lariciresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:49Z + +[Term] +id: GO:1902131 +name: (+)-lariciresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-lariciresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(+)-lariciresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(+)-lariciresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1902130 ! (+)-lariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:54Z + +[Term] +id: GO:1902132 +name: (+)-lariciresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-lariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(+)-lariciresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-lariciresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-lariciresinol formation" EXACT [GOC:TermGenie] +synonym: "(+)-lariciresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1902130 ! (+)-lariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:49:59Z + +[Term] +id: GO:1902133 +name: (+)-secoisolariciresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (+)-secoisolariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(+)-secoisolariciresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0034311 ! diol metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:04Z + +[Term] +id: GO:1902134 +name: (+)-secoisolariciresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(+)-secoisolariciresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(+)-secoisolariciresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(+)-secoisolariciresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:1902133 ! (+)-secoisolariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:09Z + +[Term] +id: GO:1902135 +name: (+)-secoisolariciresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol." [GOC:TermGenie, PMID:15949826, PMID:9872995] +synonym: "(+)-secoisolariciresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(+)-secoisolariciresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(+)-secoisolariciresinol formation" EXACT [GOC:TermGenie] +synonym: "(+)-secoisolariciresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1902133 ! (+)-secoisolariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:14Z + +[Term] +id: GO:1902136 +name: (-)-secoisolariciresinol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving (-)-secoisolariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(-)-secoisolariciresinol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009806 ! lignan metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018958 ! phenol-containing compound metabolic process +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0042445 ! hormone metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:19Z + +[Term] +id: GO:1902137 +name: (-)-secoisolariciresinol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(-)-secoisolariciresinol breakdown" EXACT [GOC:TermGenie] +synonym: "(-)-secoisolariciresinol catabolism" EXACT [GOC:TermGenie] +synonym: "(-)-secoisolariciresinol degradation" EXACT [GOC:TermGenie] +is_a: GO:0019336 ! phenol-containing compound catabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0042447 ! hormone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0046273 ! lignan catabolic process +is_a: GO:1902136 ! (-)-secoisolariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:24Z + +[Term] +id: GO:1902138 +name: (-)-secoisolariciresinol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol." [GOC:TermGenie, PMID:8910615, PMID:9872995] +synonym: "(-)-secoisolariciresinol anabolism" EXACT [GOC:TermGenie] +synonym: "(-)-secoisolariciresinol biosynthesis" EXACT [GOC:TermGenie] +synonym: "(-)-secoisolariciresinol formation" EXACT [GOC:TermGenie] +synonym: "(-)-secoisolariciresinol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009807 ! lignan biosynthetic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0042446 ! hormone biosynthetic process +is_a: GO:0046189 ! phenol-containing compound biosynthetic process +is_a: GO:1902136 ! (-)-secoisolariciresinol metabolic process +created_by: ms +creation_date: 2013-05-21T08:50:29Z + +[Term] +id: GO:1902140 +name: response to inositol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus." [GOC:TermGenie, PMID:16496115] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: al +creation_date: 2013-05-21T13:42:10Z + +[Term] +id: GO:1902141 +name: cellular response to inositol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus." [GOC:TermGenie, PMID:16496115] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902140 ! response to inositol +created_by: al +creation_date: 2013-05-21T13:42:15Z + +[Term] +id: GO:1902145 +name: regulation of response to cell cycle checkpoint signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "regulation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "regulation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "regulation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "regulation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "regulation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072396 ! response to cell cycle checkpoint signaling +relationship: regulates GO:0072396 ! response to cell cycle checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:43:40Z + +[Term] +id: GO:1902146 +name: positive regulation of response to cell cycle checkpoint signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "activation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "activation of response to cell cycle checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "activation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "activation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "activation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "activation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "positive regulation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "positive regulation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +synonym: "up regulation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "up regulation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "up regulation of response to cell cycle checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "up regulation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "up regulation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "up-regulation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "up-regulation of response to cell cycle checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +synonym: "upregulation of cell cycle checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of G1/S transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "upregulation of G2/M transition checkpoint effector process" RELATED [GOC:TermGenie] +synonym: "upregulation of response to cell cycle checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to G1/S transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of response to G2/M transition checkpoint signaling" RELATED [GOC:TermGenie] +synonym: "upregulation of response to signal involved in cell cycle checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in G1/S transition checkpoint" RELATED [GOC:TermGenie] +synonym: "upregulation of response to signal involved in G2/M transition checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1902145 ! regulation of response to cell cycle checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072396 ! response to cell cycle checkpoint signaling +relationship: positively_regulates GO:0072396 ! response to cell cycle checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:43:45Z + +[Term] +id: GO:1902147 +name: regulation of response to cytokinesis checkpoint signaling +namespace: biological_process +alt_id: GO:1902149 +def: "Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902145 ! regulation of response to cell cycle checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072399 ! response to cytokinesis checkpoint signaling +relationship: regulates GO:0072399 ! response to cytokinesis checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:43:53Z + +[Term] +id: GO:1902148 +name: positive regulation of response to cytokinesis checkpoint signaling +namespace: biological_process +alt_id: GO:1902150 +def: "Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of response to cytokinesis checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of response to cytokinesis checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to cytokinesis checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of cytokinesis checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of response to cytokinesis checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in cytokinesis checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902146 ! positive regulation of response to cell cycle checkpoint signaling +is_a: GO:1902147 ! regulation of response to cytokinesis checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072399 ! response to cytokinesis checkpoint signaling +relationship: positively_regulates GO:0072399 ! response to cytokinesis checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:43:58Z + +[Term] +id: GO:1902151 +name: regulation of response to DNA integrity checkpoint signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902145 ! regulation of response to cell cycle checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072402 ! response to DNA integrity checkpoint signaling +relationship: regulates GO:0072402 ! response to DNA integrity checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:26Z + +[Term] +id: GO:1902152 +name: positive regulation of response to DNA integrity checkpoint signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of response to DNA integrity checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of response to DNA integrity checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to DNA integrity checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA integrity checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of response to DNA integrity checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in DNA integrity checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902146 ! positive regulation of response to cell cycle checkpoint signaling +is_a: GO:1902151 ! regulation of response to DNA integrity checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072402 ! response to DNA integrity checkpoint signaling +relationship: positively_regulates GO:0072402 ! response to DNA integrity checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:31Z + +[Term] +id: GO:1902153 +name: regulation of response to DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902151 ! regulation of response to DNA integrity checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072423 ! response to DNA damage checkpoint signaling +relationship: regulates GO:0072423 ! response to DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:39Z + +[Term] +id: GO:1902154 +name: positive regulation of response to DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of response to DNA damage checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of response to DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of response to DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902152 ! positive regulation of response to DNA integrity checkpoint signaling +is_a: GO:1902153 ! regulation of response to DNA damage checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072423 ! response to DNA damage checkpoint signaling +relationship: positively_regulates GO:0072423 ! response to DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:44Z + +[Term] +id: GO:1902155 +name: regulation of response to G1 DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902153 ! regulation of response to DNA damage checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072432 ! response to G1 DNA damage checkpoint signaling +relationship: regulates GO:0072432 ! response to G1 DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:53Z + +[Term] +id: GO:1902156 +name: positive regulation of response to G1 DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of response to G1 DNA damage checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "activation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of response to G1 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to G1 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of response to G1 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902154 ! positive regulation of response to DNA damage checkpoint signaling +is_a: GO:1902155 ! regulation of response to G1 DNA damage checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072432 ! response to G1 DNA damage checkpoint signaling +relationship: positively_regulates GO:0072432 ! response to G1 DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:44:58Z + +[Term] +id: GO:1902157 +name: regulation of response to G2 DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "regulation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902153 ! regulation of response to DNA damage checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072426 ! response to G2 DNA damage checkpoint signaling +relationship: regulates GO:0072426 ! response to G2 DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:45:06Z + +[Term] +id: GO:1902158 +name: positive regulation of response to G2 DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "activation of response to G2 DNA damage checkpoint signaling" NARROW [GOC:TermGenie] +synonym: "activation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "positive regulation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up regulation of response to G2 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to G2 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of G2/M transition DNA damage checkpoint effector process" EXACT [GOC:TermGenie] +synonym: "upregulation of response to G2 DNA damage checkpoint signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of response to signal involved in G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902154 ! positive regulation of response to DNA damage checkpoint signaling +is_a: GO:1902157 ! regulation of response to G2 DNA damage checkpoint signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072426 ! response to G2 DNA damage checkpoint signaling +relationship: positively_regulates GO:0072426 ! response to G2 DNA damage checkpoint signaling +created_by: jl +creation_date: 2013-05-21T15:45:10Z + +[Term] +id: GO:1902159 +name: regulation of cyclic nucleotide-gated ion channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity." [GOC:TermGenie, PMID:11420311] +synonym: "regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +relationship: regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +created_by: sl +creation_date: 2013-05-21T19:24:30Z + +[Term] +id: GO:1902160 +name: negative regulation of cyclic nucleotide-gated ion channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity." [GOC:TermGenie, PMID:11420311] +synonym: "down regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of cyclic nucleotide-gated ion channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1902159 ! regulation of cyclic nucleotide-gated ion channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +relationship: negatively_regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +created_by: sl +creation_date: 2013-05-21T19:24:35Z + +[Term] +id: GO:1902161 +name: positive regulation of cyclic nucleotide-gated ion channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity." [GOC:TermGenie, PMID:11420311] +synonym: "activation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "activation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "activation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "activation of cyclic nucleotide-gated ion channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1902159 ! regulation of cyclic nucleotide-gated ion channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +relationship: positively_regulates GO:0043855 ! cyclic nucleotide-gated ion channel activity +created_by: sl +creation_date: 2013-05-21T19:24:48Z + +[Term] +id: GO:1902162 +name: regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator." [GOC:TermGenie, PMID:17719541] +is_a: GO:0043516 ! regulation of DNA damage response, signal transduction by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +relationship: regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +created_by: lb +creation_date: 2013-05-22T12:39:18Z + +[Term] +id: GO:1902163 +name: negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator." [GOC:TermGenie, PMID:17719541] +synonym: "down regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" NARROW [GOC:TermGenie] +is_a: GO:0043518 ! negative regulation of DNA damage response, signal transduction by p53 class mediator +is_a: GO:1902162 ! regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +relationship: negatively_regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +created_by: lb +creation_date: 2013-05-22T12:39:23Z + +[Term] +id: GO:1902164 +name: positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator." [GOC:TermGenie, PMID:17719541] +synonym: "activation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" EXACT [GOC:TermGenie] +is_a: GO:0043517 ! positive regulation of DNA damage response, signal transduction by p53 class mediator +is_a: GO:1902162 ! regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +relationship: positively_regulates GO:0006978 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +created_by: lb +creation_date: 2013-05-22T12:39:29Z + +[Term] +id: GO:1902165 +name: regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator." [GOC:TermGenie, PMID:17719541] +synonym: "regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1902229 ! regulation of intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:1902253 ! regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +relationship: regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +created_by: lb +creation_date: 2013-05-22T12:45:10Z + +[Term] +id: GO:1902166 +name: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator." [GOC:TermGenie, PMID:17719541] +synonym: "down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1902165 ! regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +is_a: GO:1902230 ! negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:1902254 ! negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +relationship: negatively_regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +created_by: lb +creation_date: 2013-05-22T12:45:15Z + +[Term] +id: GO:1902167 +name: positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator." [GOC:TermGenie, PMID:17719541] +synonym: "activation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" EXACT [GOC:TermGenie] +is_a: GO:1902165 ! regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +is_a: GO:1902231 ! positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:1902255 ! positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +relationship: positively_regulates GO:0042771 ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +created_by: lb +creation_date: 2013-05-22T12:45:20Z + +[Term] +id: GO:1902168 +name: response to catechin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus." [GOC:rjd, GOC:TermGenie, PMID:23516620] +is_a: GO:0080184 ! response to phenylpropanoid +is_a: GO:1905395 ! response to flavonoid +created_by: rjd +creation_date: 2013-05-22T17:35:35Z + +[Term] +id: GO:1902169 +name: cellular response to catechin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus." [GOC:rjd, GOC:TermGenie, PMID:23516620] +is_a: GO:1902168 ! response to catechin +is_a: GO:1905396 ! cellular response to flavonoid +is_a: GO:1905546 ! cellular response to phenylpropanoid +created_by: rjd +creation_date: 2013-05-22T17:35:40Z + +[Term] +id: GO:1902170 +name: cellular response to reactive nitrogen species +namespace: biological_process +alt_id: GO:1990106 +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus." [GOC:sl, GOC:TermGenie, PMID:22504638] +is_a: GO:1901699 ! cellular response to nitrogen compound +created_by: tb +creation_date: 2013-05-23T00:23:59Z + +[Term] +id: GO:1902171 +name: regulation of tocopherol cyclase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tocopherol cyclase activity." [GOC:TermGenie, PMID:23632854] +is_a: GO:0031279 ! regulation of cyclase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009976 ! tocopherol cyclase activity +relationship: regulates GO:0009976 ! tocopherol cyclase activity +created_by: tb +creation_date: 2013-05-25T00:41:14Z + +[Term] +id: GO:1902172 +name: regulation of keratinocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:18938133] +synonym: "regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097283 ! keratinocyte apoptotic process +relationship: regulates GO:0097283 ! keratinocyte apoptotic process +created_by: rl +creation_date: 2013-05-29T14:36:11Z + +[Term] +id: GO:1902173 +name: negative regulation of keratinocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:18938133] +synonym: "down regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of keratinocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1902172 ! regulation of keratinocyte apoptotic process +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097283 ! keratinocyte apoptotic process +relationship: negatively_regulates GO:0097283 ! keratinocyte apoptotic process +created_by: rl +creation_date: 2013-05-29T14:36:15Z + +[Term] +id: GO:1902174 +name: positive regulation of keratinocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:18938133] +synonym: "activation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of keratinocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of keratinocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of keratinocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1902172 ! regulation of keratinocyte apoptotic process +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097283 ! keratinocyte apoptotic process +relationship: positively_regulates GO:0097283 ! keratinocyte apoptotic process +created_by: rl +creation_date: 2013-05-29T14:36:21Z + +[Term] +id: GO:1902175 +name: regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie, PMID:11672522] +synonym: "regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:bf] +is_a: GO:1903201 ! regulation of oxidative stress-induced cell death +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: pr +creation_date: 2013-05-29T18:30:00Z + +[Term] +id: GO:1902176 +name: negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie, PMID:11672522] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:bf] +is_a: GO:1902175 ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903202 ! negative regulation of oxidative stress-induced cell death +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: negatively_regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: pr +creation_date: 2013-05-29T18:30:05Z + +[Term] +id: GO:1902177 +name: positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie, PMID:11672522] +synonym: "activation of intrinsic apoptotic signaling pathway in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:bf] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:1902175 ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903209 ! positive regulation of oxidative stress-induced cell death +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: positively_regulates GO:0008631 ! intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: pr +creation_date: 2013-05-29T18:30:10Z + +[Term] +id: GO:1902178 +name: fibroblast growth factor receptor apoptotic signaling pathway +namespace: biological_process +def: "An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR)." [GOC:mtg_apoptosis, GOC:pm, GOC:pr, GOC:TermGenie, PMID:17561467] +synonym: "FGF receptor signaling pathway involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "FGF receptor signaling pathway involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "FGF receptor signalling pathway involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "FGFR signaling pathway involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in apoptotic process" EXACT [GOC:pm] +synonym: "fibroblast growth factor receptor signaling pathway involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signaling pathway involved in type I programmed cell death" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in apoptotic cell death" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in apoptotic process" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in apoptotic program" NARROW [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in apoptotic programmed cell death" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in programmed cell death by apoptosis" EXACT [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in signaling (initiator) caspase activity" RELATED [GOC:TermGenie] +synonym: "fibroblast growth factor receptor signalling pathway involved in type I programmed cell death" NARROW [GOC:TermGenie] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +is_a: GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pm +creation_date: 2013-05-30T13:59:57Z + +[Term] +id: GO:1902179 +name: verruculogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving verruculogen." [GOC:di, GOC:TermGenie, PMID:23649274] +synonym: "verruculogen metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0018904 ! ether metabolic process +is_a: GO:0034311 ! diol metabolic process +is_a: GO:0035834 ! indole alkaloid metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: di +creation_date: 2013-05-30T17:44:25Z + +[Term] +id: GO:1902180 +name: verruculogen catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of verruculogen." [GOC:di, GOC:TermGenie, PMID:23649274] +synonym: "verruculogen breakdown" EXACT [GOC:TermGenie] +synonym: "verruculogen catabolism" EXACT [GOC:TermGenie] +synonym: "verruculogen degradation" EXACT [GOC:TermGenie] +is_a: GO:0009822 ! alkaloid catabolic process +is_a: GO:0019439 ! aromatic compound catabolic process +is_a: GO:0034313 ! diol catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:1901502 ! ether catabolic process +is_a: GO:1902179 ! verruculogen metabolic process +created_by: di +creation_date: 2013-05-30T17:44:30Z + +[Term] +id: GO:1902181 +name: verruculogen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of verruculogen." [GOC:di, GOC:TermGenie, PMID:23649274] +synonym: "verruculogen anabolism" EXACT [GOC:TermGenie] +synonym: "verruculogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "verruculogen formation" EXACT [GOC:TermGenie] +synonym: "verruculogen synthesis" EXACT [GOC:TermGenie] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0034312 ! diol biosynthetic process +is_a: GO:0035835 ! indole alkaloid biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901503 ! ether biosynthetic process +is_a: GO:1902179 ! verruculogen metabolic process +created_by: di +creation_date: 2013-05-30T17:44:35Z + +[Term] +id: GO:1902182 +name: shoot apical meristem development +namespace: biological_process +def: "The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure." [GOC:TermGenie, PMID:21496644] +synonym: "primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "promeristem development" BROAD [GOC:TermGenie] +synonym: "SAM development" EXACT [GOC:TermGenie] +is_a: GO:0048507 ! meristem development +created_by: tb +creation_date: 2013-05-30T23:13:21Z + +[Term] +id: GO:1902183 +name: regulation of shoot apical meristem development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shoot apical meristem development." [GOC:TermGenie, PMID:21496644] +synonym: "regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "regulation of SAM development" EXACT [GOC:TermGenie] +is_a: GO:0048509 ! regulation of meristem development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902182 ! shoot apical meristem development +relationship: regulates GO:1902182 ! shoot apical meristem development +created_by: tb +creation_date: 2013-05-31T16:33:55Z + +[Term] +id: GO:1902184 +name: negative regulation of shoot apical meristem development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development." [GOC:TermGenie, PMID:21496644] +synonym: "down regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "down regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "down regulation of SAM development" EXACT [GOC:TermGenie] +synonym: "down regulation of shoot apical meristem development" EXACT [GOC:TermGenie] +synonym: "down-regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "down-regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "down-regulation of SAM development" EXACT [GOC:TermGenie] +synonym: "down-regulation of shoot apical meristem development" EXACT [GOC:TermGenie] +synonym: "downregulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "downregulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "downregulation of SAM development" EXACT [GOC:TermGenie] +synonym: "downregulation of shoot apical meristem development" EXACT [GOC:TermGenie] +synonym: "inhibition of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "inhibition of promeristem development" BROAD [GOC:TermGenie] +synonym: "inhibition of SAM development" EXACT [GOC:TermGenie] +synonym: "inhibition of shoot apical meristem development" NARROW [GOC:TermGenie] +synonym: "negative regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "negative regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "negative regulation of SAM development" EXACT [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1902183 ! regulation of shoot apical meristem development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902182 ! shoot apical meristem development +relationship: negatively_regulates GO:1902182 ! shoot apical meristem development +created_by: tb +creation_date: 2013-05-31T16:34:00Z + +[Term] +id: GO:1902185 +name: positive regulation of shoot apical meristem development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of shoot apical meristem development." [GOC:TermGenie, PMID:21496644] +synonym: "activation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "activation of promeristem development" BROAD [GOC:TermGenie] +synonym: "activation of SAM development" EXACT [GOC:TermGenie] +synonym: "activation of shoot apical meristem development" NARROW [GOC:TermGenie] +synonym: "positive regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "positive regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "positive regulation of SAM development" EXACT [GOC:TermGenie] +synonym: "up regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "up regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "up regulation of SAM development" EXACT [GOC:TermGenie] +synonym: "up regulation of shoot apical meristem development" EXACT [GOC:TermGenie] +synonym: "up-regulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "up-regulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "up-regulation of SAM development" EXACT [GOC:TermGenie] +synonym: "up-regulation of shoot apical meristem development" EXACT [GOC:TermGenie] +synonym: "upregulation of primary shoot meristem development" RELATED [GOC:TermGenie] +synonym: "upregulation of promeristem development" BROAD [GOC:TermGenie] +synonym: "upregulation of SAM development" EXACT [GOC:TermGenie] +synonym: "upregulation of shoot apical meristem development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1902183 ! regulation of shoot apical meristem development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902182 ! shoot apical meristem development +relationship: positively_regulates GO:1902182 ! shoot apical meristem development +created_by: tb +creation_date: 2013-05-31T16:34:05Z + +[Term] +id: GO:1902186 +name: regulation of viral release from host cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral release from host cell." [GOC:TermGenie, PMID:18305167] +synonym: "regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "regulation of viral release" EXACT [GOC:TermGenie] +synonym: "regulation of viral shedding" EXACT [GOC:TermGenie] +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019076 ! viral release from host cell +relationship: regulates GO:0019076 ! viral release from host cell +created_by: ss +creation_date: 2013-06-04T03:54:03Z + +[Term] +id: GO:1902187 +name: negative regulation of viral release from host cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell." [GOC:TermGenie, PMID:18305167] +synonym: "down regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "down regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "down regulation of viral release" EXACT [GOC:TermGenie] +synonym: "down regulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "down regulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "down-regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral release" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "downregulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "downregulation of viral exit" EXACT [GOC:TermGenie] +synonym: "downregulation of viral release" EXACT [GOC:TermGenie] +synonym: "downregulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "downregulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "inhibition of release of virus from host" EXACT [GOC:TermGenie] +synonym: "inhibition of viral exit" EXACT [GOC:TermGenie] +synonym: "inhibition of viral release" EXACT [GOC:TermGenie] +synonym: "inhibition of viral release from host cell" NARROW [GOC:TermGenie] +synonym: "inhibition of viral shedding" EXACT [GOC:TermGenie] +synonym: "negative regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral release" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral shedding" EXACT [GOC:TermGenie] +is_a: GO:1902186 ! regulation of viral release from host cell +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019076 ! viral release from host cell +relationship: negatively_regulates GO:0019076 ! viral release from host cell +created_by: ss +creation_date: 2013-06-04T03:54:08Z + +[Term] +id: GO:1902188 +name: positive regulation of viral release from host cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral release from host cell." [GOC:TermGenie, PMID:18305167] +synonym: "activation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "activation of viral exit" EXACT [GOC:TermGenie] +synonym: "activation of viral release" EXACT [GOC:TermGenie] +synonym: "activation of viral release from host cell" NARROW [GOC:TermGenie] +synonym: "activation of viral shedding" EXACT [GOC:TermGenie] +synonym: "positive regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral release" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "up regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "up regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "up regulation of viral release" EXACT [GOC:TermGenie] +synonym: "up regulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "up regulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "up-regulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral exit" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral release" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral shedding" EXACT [GOC:TermGenie] +synonym: "upregulation of release of virus from host" EXACT [GOC:TermGenie] +synonym: "upregulation of viral exit" EXACT [GOC:TermGenie] +synonym: "upregulation of viral release" EXACT [GOC:TermGenie] +synonym: "upregulation of viral release from host cell" EXACT [GOC:TermGenie] +synonym: "upregulation of viral shedding" EXACT [GOC:TermGenie] +is_a: GO:1902186 ! regulation of viral release from host cell +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019076 ! viral release from host cell +relationship: positively_regulates GO:0019076 ! viral release from host cell +created_by: ss +creation_date: 2013-06-04T03:54:14Z + +[Term] +id: GO:1902189 +name: 2-methylbutanoyl-CoA(4-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbutanoyl-CoA(4-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:14Z + +[Term] +id: GO:1902190 +name: 2-methylbutanoyl-CoA(4-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbutanoyl-CoA(4-) breakdown" EXACT [GOC:TermGenie] +synonym: "2-methylbutanoyl-CoA(4-) catabolism" EXACT [GOC:TermGenie] +synonym: "2-methylbutanoyl-CoA(4-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +is_a: GO:1902189 ! 2-methylbutanoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:20Z + +[Term] +id: GO:1902191 +name: 2-methylbutanoyl-CoA(4-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbutanoyl-CoA(4-) anabolism" EXACT [GOC:TermGenie] +synonym: "2-methylbutanoyl-CoA(4-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "2-methylbutanoyl-CoA(4-) formation" EXACT [GOC:TermGenie] +synonym: "2-methylbutanoyl-CoA(4-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +is_a: GO:1902189 ! 2-methylbutanoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:25Z + +[Term] +id: GO:1902192 +name: 2-methylbut-2-enoyl-CoA(4-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbut-2-enoyl-CoA(4-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:30Z + +[Term] +id: GO:1902193 +name: 2-methylbut-2-enoyl-CoA(4-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbut-2-enoyl-CoA(4-) breakdown" EXACT [GOC:TermGenie] +synonym: "2-methylbut-2-enoyl-CoA(4-) catabolism" EXACT [GOC:TermGenie] +synonym: "2-methylbut-2-enoyl-CoA(4-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +is_a: GO:1902192 ! 2-methylbut-2-enoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:41Z + +[Term] +id: GO:1902194 +name: 2-methylbut-2-enoyl-CoA(4-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, PMID:15574432] +synonym: "2-methylbut-2-enoyl-CoA(4-) anabolism" EXACT [GOC:TermGenie] +synonym: "2-methylbut-2-enoyl-CoA(4-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "2-methylbut-2-enoyl-CoA(4-) formation" EXACT [GOC:TermGenie] +synonym: "2-methylbut-2-enoyl-CoA(4-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +is_a: GO:1902192 ! 2-methylbut-2-enoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:40:46Z + +[Term] +id: GO:1902195 +name: isovaleryl-CoA(4-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isovaleryl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "isovaleryl-CoA(4-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: ms +creation_date: 2013-06-06T09:55:55Z + +[Term] +id: GO:1902196 +name: isovaleryl-CoA(4-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "isovaleryl-CoA(4-) breakdown" EXACT [GOC:TermGenie] +synonym: "isovaleryl-CoA(4-) catabolism" EXACT [GOC:TermGenie] +synonym: "isovaleryl-CoA(4-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +is_a: GO:1902195 ! isovaleryl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:56:00Z + +[Term] +id: GO:1902197 +name: isovaleryl-CoA(4-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "isovaleryl-CoA(4-) anabolism" EXACT [GOC:TermGenie] +synonym: "isovaleryl-CoA(4-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "isovaleryl-CoA(4-) formation" EXACT [GOC:TermGenie] +synonym: "isovaleryl-CoA(4-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +is_a: GO:1902195 ! isovaleryl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:56:05Z + +[Term] +id: GO:1902198 +name: 3-methylbut-2-enoyl-CoA(4-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "3-methylbut-2-enoyl-CoA(4-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: ms +creation_date: 2013-06-06T09:56:11Z + +[Term] +id: GO:1902199 +name: 3-methylbut-2-enoyl-CoA(4-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "3-methylbut-2-enoyl-CoA(4-) breakdown" EXACT [GOC:TermGenie] +synonym: "3-methylbut-2-enoyl-CoA(4-) catabolism" EXACT [GOC:TermGenie] +synonym: "3-methylbut-2-enoyl-CoA(4-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +is_a: GO:1902198 ! 3-methylbut-2-enoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:56:16Z + +[Term] +id: GO:1902200 +name: 3-methylbut-2-enoyl-CoA(4-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-)." [GOC:TermGenie, pmid:11231285] +synonym: "3-methylbut-2-enoyl-CoA(4-) anabolism" EXACT [GOC:TermGenie] +synonym: "3-methylbut-2-enoyl-CoA(4-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "3-methylbut-2-enoyl-CoA(4-) formation" EXACT [GOC:TermGenie] +synonym: "3-methylbut-2-enoyl-CoA(4-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +is_a: GO:1902198 ! 3-methylbut-2-enoyl-CoA(4-) metabolic process +created_by: ms +creation_date: 2013-06-06T09:56:21Z + +[Term] +id: GO:1902201 +name: negative regulation of bacterial-type flagellum-dependent cell motility +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] +synonym: "down regulation of bacterial-type flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "down regulation of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "down-regulation of bacterial-type flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "down-regulation of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "downregulation of bacterial-type flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "downregulation of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "inhibition of bacterial-type flagellar cell motility" NARROW [GOC:TermGenie] +synonym: "inhibition of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +synonym: "negative regulation of bacterial-type flagellar cell motility" RELATED [] +synonym: "negative regulation of flagellin-based flagellar cell motility" EXACT [GOC:TermGenie] +is_a: GO:1902021 ! regulation of bacterial-type flagellum-dependent cell motility +is_a: GO:2000146 ! negative regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071973 ! bacterial-type flagellum-dependent cell motility +relationship: negatively_regulates GO:0071973 ! bacterial-type flagellum-dependent cell motility +created_by: jl +creation_date: 2013-06-06T14:58:41Z + +[Term] +id: GO:1902202 +name: regulation of hepatocyte growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway." [GOC:TermGenie, PMID:18819921] +synonym: "regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of Met signaling pathway" NARROW [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +relationship: regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +created_by: lb +creation_date: 2013-06-10T13:20:45Z + +[Term] +id: GO:1902203 +name: negative regulation of hepatocyte growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway." [GOC:TermGenie, PMID:18819921] +synonym: "down regulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of hepatocyte growth factor receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of Met signaling pathway" NARROW [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902202 ! regulation of hepatocyte growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +relationship: negatively_regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +created_by: lb +creation_date: 2013-06-10T13:20:51Z + +[Term] +id: GO:1902204 +name: positive regulation of hepatocyte growth factor receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway." [GOC:TermGenie, PMID:18819921] +synonym: "activation of hepatocyte growth factor receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "activation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "activation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of Met signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of hepatocyte growth factor receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of HGF receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of HGF receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of Met signaling pathway" NARROW [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902202 ! regulation of hepatocyte growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +relationship: positively_regulates GO:0048012 ! hepatocyte growth factor receptor signaling pathway +created_by: lb +creation_date: 2013-06-10T13:20:56Z + +[Term] +id: GO:1902205 +name: regulation of interleukin-2-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway." [GOC:TermGenie, PMID:11909529] +synonym: "regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038110 ! interleukin-2-mediated signaling pathway +relationship: regulates GO:0038110 ! interleukin-2-mediated signaling pathway +created_by: lb +creation_date: 2013-06-11T07:34:39Z + +[Term] +id: GO:1902206 +name: negative regulation of interleukin-2-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway." [GOC:TermGenie, PMID:11909529] +synonym: "down regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of IL-2-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-2-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-2-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1902205 ! regulation of interleukin-2-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038110 ! interleukin-2-mediated signaling pathway +relationship: negatively_regulates GO:0038110 ! interleukin-2-mediated signaling pathway +created_by: lb +creation_date: 2013-06-11T07:34:45Z + +[Term] +id: GO:1902207 +name: positive regulation of interleukin-2-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway." [GOC:TermGenie, PMID:11909529] +synonym: "activation of IL-2-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-2-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-2-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-2-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-2-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1902205 ! regulation of interleukin-2-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038110 ! interleukin-2-mediated signaling pathway +relationship: positively_regulates GO:0038110 ! interleukin-2-mediated signaling pathway +created_by: lb +creation_date: 2013-06-11T07:34:50Z + +[Term] +id: GO:1902208 +name: regulation of bacterial-type flagellum assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly." [GOC:jl, GOC:TermGenie] +synonym: "regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +is_a: GO:0060491 ! regulation of cell projection assembly +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044780 ! bacterial-type flagellum assembly +relationship: regulates GO:0044780 ! bacterial-type flagellum assembly +created_by: jl +creation_date: 2013-06-11T14:20:19Z + +[Term] +id: GO:1902209 +name: negative regulation of bacterial-type flagellum assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly." [GOC:jl, GOC:TermGenie] +synonym: "down regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of bacterial flagellum assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of bacterial-type flagellum assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:1902208 ! regulation of bacterial-type flagellum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044780 ! bacterial-type flagellum assembly +relationship: negatively_regulates GO:0044780 ! bacterial-type flagellum assembly +created_by: jl +creation_date: 2013-06-11T14:20:24Z + +[Term] +id: GO:1902210 +name: positive regulation of bacterial-type flagellum assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly." [GOC:jl, GOC:TermGenie] +synonym: "activation of bacterial flagellum assembly" NARROW [GOC:TermGenie] +synonym: "activation of bacterial-type flagellum assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of bacterial flagellum assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of bacterial-type flagellum assembly" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:1902208 ! regulation of bacterial-type flagellum assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044780 ! bacterial-type flagellum assembly +relationship: positively_regulates GO:0044780 ! bacterial-type flagellum assembly +created_by: jl +creation_date: 2013-06-11T14:20:30Z + +[Term] +id: GO:1902211 +name: regulation of prolactin signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of prolactin signaling pathway." [GOC:TermGenie, PMID:11773439] +synonym: "regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038161 ! prolactin signaling pathway +relationship: regulates GO:0038161 ! prolactin signaling pathway +created_by: lb +creation_date: 2013-06-12T10:10:07Z + +[Term] +id: GO:1902212 +name: negative regulation of prolactin signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway." [GOC:TermGenie, PMID:11773439] +synonym: "down regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of PRL signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of prolactin signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of prolactin-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1902211 ! regulation of prolactin signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038161 ! prolactin signaling pathway +relationship: negatively_regulates GO:0038161 ! prolactin signaling pathway +created_by: lb +creation_date: 2013-06-12T10:10:12Z + +[Term] +id: GO:1902213 +name: positive regulation of prolactin signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway." [GOC:TermGenie, PMID:11773439] +synonym: "activation of PRL signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of prolactin signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of prolactin-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of PRL signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of prolactin signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of prolactin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1902211 ! regulation of prolactin signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038161 ! prolactin signaling pathway +relationship: positively_regulates GO:0038161 ! prolactin signaling pathway +created_by: lb +creation_date: 2013-06-12T10:10:18Z + +[Term] +id: GO:1902214 +name: regulation of interleukin-4-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway." [GOC:TermGenie, PMID:17210636] +synonym: "regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035771 ! interleukin-4-mediated signaling pathway +relationship: regulates GO:0035771 ! interleukin-4-mediated signaling pathway +created_by: lb +creation_date: 2013-06-12T12:53:09Z + +[Term] +id: GO:1902215 +name: negative regulation of interleukin-4-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway." [GOC:TermGenie, PMID:17210636] +synonym: "down regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of IL-4-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-4-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-4-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1902214 ! regulation of interleukin-4-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035771 ! interleukin-4-mediated signaling pathway +relationship: negatively_regulates GO:0035771 ! interleukin-4-mediated signaling pathway +created_by: lb +creation_date: 2013-06-12T12:53:14Z + +[Term] +id: GO:1902216 +name: positive regulation of interleukin-4-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway." [GOC:TermGenie, PMID:17210636] +synonym: "activation of IL-4-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-4-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-4-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-4-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-4-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1902214 ! regulation of interleukin-4-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035771 ! interleukin-4-mediated signaling pathway +relationship: positively_regulates GO:0035771 ! interleukin-4-mediated signaling pathway +created_by: lb +creation_date: 2013-06-12T12:53:20Z + +[Term] +id: GO:1902217 +name: erythrocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0033028 ! myeloid cell apoptotic process +property_value: RO:0002161 NCBITaxon:4751 +created_by: rl +creation_date: 2013-06-13T10:02:29Z + +[Term] +id: GO:1902218 +name: regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +is_a: GO:0106049 ! regulation of cellular response to osmotic stress +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +relationship: regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +created_by: rl +creation_date: 2013-06-13T10:19:07Z + +[Term] +id: GO:1902219 +name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress" NARROW [GOC:TermGenie] +is_a: GO:1902218 ! regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +relationship: negatively_regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +created_by: rl +creation_date: 2013-06-13T10:19:12Z + +[Term] +id: GO:1902220 +name: positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "activation of intrinsic apoptotic signaling pathway in response to osmotic stress" NARROW [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress" EXACT [GOC:TermGenie] +is_a: GO:1902218 ! regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +relationship: positively_regulates GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +created_by: rl +creation_date: 2013-06-13T10:19:18Z + +[Term] +id: GO:1902221 +name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid." [GOC:pr, GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: pr +creation_date: 2013-06-13T10:37:38Z + +[Term] +id: GO:1902222 +name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid." [GOC:pr, GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid breakdown" EXACT [GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolism" EXACT [GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid degradation" EXACT [GOC:TermGenie] +is_a: GO:1901606 ! alpha-amino acid catabolic process +is_a: GO:1902221 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process +created_by: pr +creation_date: 2013-06-13T10:37:43Z + +[Term] +id: GO:1902223 +name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid." [GOC:pr, GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid anabolism" EXACT [GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid formation" EXACT [GOC:TermGenie] +synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +is_a: GO:1902221 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process +created_by: pr +creation_date: 2013-06-13T10:37:49Z + +[Term] +id: GO:1902224 +name: ketone body metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ketone body." [GOC:pr, GOC:TermGenie] +synonym: "ketone body metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006091 ! generation of precursor metabolites and energy +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901568 ! fatty acid derivative metabolic process +created_by: pr +creation_date: 2013-06-13T10:37:54Z + +[Term] +id: GO:1902225 +name: negative regulation of acrosome reaction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction." [GOC:TermGenie, PMID:23430248] +synonym: "down regulation of acrosome reaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of acrosome reaction" EXACT [GOC:TermGenie] +synonym: "downregulation of acrosome reaction" EXACT [GOC:TermGenie] +synonym: "inhibition of acrosome reaction" NARROW [GOC:TermGenie] +is_a: GO:0060046 ! regulation of acrosome reaction +is_a: GO:0060467 ! negative regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007340 ! acrosome reaction +relationship: negatively_regulates GO:0007340 ! acrosome reaction +created_by: ae +creation_date: 2013-06-13T14:17:11Z + +[Term] +id: GO:1902226 +name: regulation of macrophage colony-stimulating factor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway." [GOC:TermGenie, PMID:16705167] +synonym: "regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +is_a: GO:1903972 ! regulation of cellular response to macrophage colony-stimulating factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +relationship: regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +created_by: lb +creation_date: 2013-06-14T06:28:42Z + +[Term] +id: GO:1902227 +name: negative regulation of macrophage colony-stimulating factor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway." [GOC:TermGenie, PMID:16705167] +synonym: "down regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of M-CSF signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of macrophage colony-stimulating factor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of macrophage colony-stimulating factor signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1902226 ! regulation of macrophage colony-stimulating factor signaling pathway +is_a: GO:1903973 ! negative regulation of cellular response to macrophage colony-stimulating factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +relationship: negatively_regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +created_by: lb +creation_date: 2013-06-14T06:28:54Z + +[Term] +id: GO:1902228 +name: positive regulation of macrophage colony-stimulating factor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway." [GOC:TermGenie, PMID:16705167] +synonym: "activation of M-CSF signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of macrophage colony-stimulating factor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of macrophage colony-stimulating factor signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of M-CSF signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of macrophage colony-stimulating factor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of macrophage colony-stimulating factor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1902226 ! regulation of macrophage colony-stimulating factor signaling pathway +is_a: GO:1903974 ! positive regulation of cellular response to macrophage colony-stimulating factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +relationship: positively_regulates GO:0038145 ! macrophage colony-stimulating factor signaling pathway +created_by: lb +creation_date: 2013-06-14T06:29:00Z + +[Term] +id: GO:1902229 +name: regulation of intrinsic apoptotic signaling pathway in response to DNA damage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15314165] +synonym: "regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +relationship: regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +created_by: rl +creation_date: 2013-06-14T09:39:52Z + +[Term] +id: GO:1902230 +name: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15314165] +synonym: "down regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to DNA damage" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1902229 ! regulation of intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:2001021 ! negative regulation of response to DNA damage stimulus +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +relationship: negatively_regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +created_by: rl +creation_date: 2013-06-14T09:39:58Z + +[Term] +id: GO:1902231 +name: positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15314165] +synonym: "activation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to DNA damage" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA damage response, signal transduction resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to DNA damage" EXACT [GOC:TermGenie] +is_a: GO:1902229 ! regulation of intrinsic apoptotic signaling pathway in response to DNA damage +is_a: GO:2001022 ! positive regulation of response to DNA damage stimulus +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +relationship: positively_regulates GO:0008630 ! intrinsic apoptotic signaling pathway in response to DNA damage +created_by: rl +creation_date: 2013-06-14T09:40:03Z + +[Term] +id: GO:1902232 +name: regulation of positive thymic T cell selection +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of positive thymic T cell selection." [GOC:TermGenie, PMID:22080863] +synonym: "regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +is_a: GO:0033081 ! regulation of T cell differentiation in thymus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045059 ! positive thymic T cell selection +relationship: regulates GO:0045059 ! positive thymic T cell selection +created_by: lb +creation_date: 2013-06-14T11:19:09Z + +[Term] +id: GO:1902233 +name: negative regulation of positive thymic T cell selection +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection." [GOC:TermGenie, PMID:22080863] +synonym: "down regulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "down regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "down regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "down regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "downregulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "downregulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "downregulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "downregulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "inhibition of positive thymic T cell selection" NARROW [GOC:TermGenie] +synonym: "inhibition of positive thymic T lymphocyte selection" NARROW [GOC:TermGenie] +synonym: "inhibition of positive thymic T-cell selection" NARROW [GOC:TermGenie] +synonym: "inhibition of positive thymic T-lymphocyte selection" NARROW [GOC:TermGenie] +synonym: "negative regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "negative regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "negative regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +is_a: GO:0033085 ! negative regulation of T cell differentiation in thymus +is_a: GO:1902232 ! regulation of positive thymic T cell selection +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045059 ! positive thymic T cell selection +relationship: negatively_regulates GO:0045059 ! positive thymic T cell selection +created_by: lb +creation_date: 2013-06-14T11:19:15Z + +[Term] +id: GO:1902234 +name: positive regulation of positive thymic T cell selection +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection." [GOC:TermGenie, PMID:22080863] +synonym: "activation of positive thymic T cell selection" NARROW [GOC:TermGenie] +synonym: "activation of positive thymic T lymphocyte selection" NARROW [GOC:TermGenie] +synonym: "activation of positive thymic T-cell selection" NARROW [GOC:TermGenie] +synonym: "activation of positive thymic T-lymphocyte selection" NARROW [GOC:TermGenie] +synonym: "positive regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "positive regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "positive regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "up regulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "up regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "up regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "up regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "up-regulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "up-regulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "up-regulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "up-regulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "upregulation of positive thymic T cell selection" EXACT [GOC:TermGenie] +synonym: "upregulation of positive thymic T lymphocyte selection" EXACT [GOC:TermGenie] +synonym: "upregulation of positive thymic T-cell selection" EXACT [GOC:TermGenie] +synonym: "upregulation of positive thymic T-lymphocyte selection" EXACT [GOC:TermGenie] +is_a: GO:0033089 ! positive regulation of T cell differentiation in thymus +is_a: GO:1902232 ! regulation of positive thymic T cell selection +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045059 ! positive thymic T cell selection +relationship: positively_regulates GO:0045059 ! positive thymic T cell selection +created_by: lb +creation_date: 2013-06-14T11:19:20Z + +[Term] +id: GO:1902235 +name: regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:20160352] +synonym: "regulation of apoptosis in response to endoplasmic reticulum stress" BROAD [GOC:TermGenie] +synonym: "regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +created_by: rl +creation_date: 2013-06-18T15:19:37Z + +[Term] +id: GO:1902236 +name: negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:20160352] +synonym: "down regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptosis in response to ER stress" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis triggered by ER stress" NARROW [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum stress-induced apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of ER stress-induced apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:1902235 ! regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903573 ! negative regulation of response to endoplasmic reticulum stress +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: negatively_regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +created_by: rl +creation_date: 2013-06-18T15:19:43Z + +[Term] +id: GO:1902237 +name: positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:20160352] +synonym: "activation of apoptosis in response to ER stress" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis triggered by ER stress" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum stress-induced apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of ER stress-induced apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "up regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptosis in response to ER stress" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptosis triggered by ER stress" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of ER stress-induced apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:1902235 ! regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1905898 ! positive regulation of response to endoplasmic reticulum stress +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: positively_regulates GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +created_by: rl +creation_date: 2013-06-18T15:19:49Z + +[Term] +id: GO:1902238 +name: regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator." [GOC:krc, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16571598] +is_a: GO:1902218 ! regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:1902253 ! regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +relationship: regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +created_by: pr +creation_date: 2013-06-19T14:00:34Z + +[Term] +id: GO:1902239 +name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator." [GOC:krc, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16571598] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" NARROW [GOC:TermGenie] +is_a: GO:1902219 ! negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:1902238 ! regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +is_a: GO:1902254 ! negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +relationship: negatively_regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +created_by: pr +creation_date: 2013-06-19T14:00:39Z + +[Term] +id: GO:1902240 +name: positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator." [GOC:krc, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16571598] +synonym: "activation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator" EXACT [GOC:TermGenie] +is_a: GO:1902220 ! positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:1902238 ! regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +is_a: GO:1902255 ! positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +relationship: positively_regulates GO:1990127 ! intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +created_by: pr +creation_date: 2013-06-19T14:00:44Z + +[Term] +id: GO:1902241 +name: copal-8-ol diphosphate(3-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving copal-8-ol diphosphate(3-)." [GOC:TermGenie, pmid:22672125] +synonym: "copal-8-ol diphosphate(3-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0016101 ! diterpenoid metabolic process +created_by: ms +creation_date: 2013-06-20T09:09:27Z + +[Term] +id: GO:1902242 +name: copal-8-ol diphosphate(3-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-)." [GOC:TermGenie, pmid:22672125] +synonym: "copal-8-ol diphosphate(3-) breakdown" EXACT [GOC:TermGenie] +synonym: "copal-8-ol diphosphate(3-) catabolism" EXACT [GOC:TermGenie] +synonym: "copal-8-ol diphosphate(3-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0016103 ! diterpenoid catabolic process +is_a: GO:1902241 ! copal-8-ol diphosphate(3-) metabolic process +created_by: ms +creation_date: 2013-06-20T09:09:33Z + +[Term] +id: GO:1902243 +name: copal-8-ol diphosphate(3-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-)." [GOC:TermGenie, pmid:22672125] +synonym: "copal-8-ol diphosphate(3-) anabolism" EXACT [GOC:TermGenie] +synonym: "copal-8-ol diphosphate(3-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "copal-8-ol diphosphate(3-) formation" EXACT [GOC:TermGenie] +synonym: "copal-8-ol diphosphate(3-) synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:1902241 ! copal-8-ol diphosphate(3-) metabolic process +created_by: ms +creation_date: 2013-06-20T09:09:38Z + +[Term] +id: GO:1902244 +name: cis-abienol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cis-abienol." [GOC:TermGenie, pmid:22672125] +synonym: "cis-abienol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016101 ! diterpenoid metabolic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: ms +creation_date: 2013-06-20T09:09:51Z + +[Term] +id: GO:1902245 +name: cis-abienol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cis-abienol." [GOC:TermGenie, pmid:22672125] +synonym: "cis-abienol breakdown" EXACT [GOC:TermGenie] +synonym: "cis-abienol catabolism" EXACT [GOC:TermGenie] +synonym: "cis-abienol degradation" EXACT [GOC:TermGenie] +is_a: GO:0016103 ! diterpenoid catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1902244 ! cis-abienol metabolic process +created_by: ms +creation_date: 2013-06-20T09:09:57Z + +[Term] +id: GO:1902246 +name: cis-abienol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cis-abienol." [GOC:TermGenie, pmid:22672125] +synonym: "cis-abienol anabolism" EXACT [GOC:TermGenie] +synonym: "cis-abienol biosynthesis" EXACT [GOC:TermGenie] +synonym: "cis-abienol formation" EXACT [GOC:TermGenie] +synonym: "cis-abienol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016102 ! diterpenoid biosynthetic process +is_a: GO:1902244 ! cis-abienol metabolic process +is_a: GO:1902645 ! tertiary alcohol biosynthetic process +created_by: ms +creation_date: 2013-06-20T09:10:02Z + +[Term] +id: GO:1902247 +name: geranylgeranyl diphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate." [GOC:TermGenie, pmid:22672125] +synonym: "geranylgeranyl diphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "geranylgeranyl diphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "geranylgeranyl diphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0016115 ! terpenoid catabolic process +is_a: GO:0033385 ! geranylgeranyl diphosphate metabolic process +created_by: ms +creation_date: 2013-06-20T09:10:09Z + +[Term] +id: GO:1902248 +name: 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5-O-phosphono-alpha-D-ribofuranosyl diphosphate." [GOC:mah, GOC:TermGenie, PMID:4314233] +synonym: "5-phosphoribose 1-diphosphate binding" EXACT [] +synonym: "phosphoribosylpyrophosphate binding" EXACT [GOC:al] +is_a: GO:0043168 ! anion binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: mah +creation_date: 2013-06-20T16:20:29Z + +[Term] +id: GO:1902249 +name: IMP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with IMP, inosine monophosphate." [GOC:mah, GOC:TermGenie, PMID:4314233] +is_a: GO:0032555 ! purine ribonucleotide binding +is_a: GO:0043168 ! anion binding +created_by: mah +creation_date: 2013-06-20T16:20:35Z + +[Term] +id: GO:1902250 +name: regulation of erythrocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902217 ! erythrocyte apoptotic process +relationship: regulates GO:1902217 ! erythrocyte apoptotic process +created_by: rl +creation_date: 2013-06-20T19:30:53Z + +[Term] +id: GO:1902251 +name: negative regulation of erythrocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "down regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of erythrocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of RBC apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of red blood cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process +is_a: GO:1902250 ! regulation of erythrocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902217 ! erythrocyte apoptotic process +relationship: negatively_regulates GO:1902217 ! erythrocyte apoptotic process +property_value: RO:0002161 NCBITaxon:4751 +created_by: rl +creation_date: 2013-06-20T19:30:59Z + +[Term] +id: GO:1902252 +name: positive regulation of erythrocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] +synonym: "activation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of erythrocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of RBC apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of red blood cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of RBC apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process +is_a: GO:1902250 ! regulation of erythrocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902217 ! erythrocyte apoptotic process +relationship: positively_regulates GO:1902217 ! erythrocyte apoptotic process +property_value: RO:0002161 NCBITaxon:4751 +created_by: rl +creation_date: 2013-06-20T19:31:04Z + +[Term] +id: GO:1902253 +name: regulation of intrinsic apoptotic signaling pathway by p53 class mediator +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15705871] +synonym: "regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1901796 ! regulation of signal transduction by p53 class mediator +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +relationship: regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +created_by: rl +creation_date: 2013-06-20T19:41:38Z + +[Term] +id: GO:1902254 +name: negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15705871] +synonym: "down regulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1901797 ! negative regulation of signal transduction by p53 class mediator +is_a: GO:1902253 ! regulation of intrinsic apoptotic signaling pathway by p53 class mediator +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +relationship: negatively_regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +created_by: rl +creation_date: 2013-06-20T19:41:43Z + +[Term] +id: GO:1902255 +name: positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:15705871] +synonym: "activation of intrinsic apoptotic signaling pathway by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" NARROW [GOC:TermGenie] +synonym: "activation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "positive regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "up-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator" EXACT [GOC:TermGenie] +synonym: "upregulation of signal transduction by p53 class mediator resulting in induction of apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1901798 ! positive regulation of signal transduction by p53 class mediator +is_a: GO:1902253 ! regulation of intrinsic apoptotic signaling pathway by p53 class mediator +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +relationship: positively_regulates GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +created_by: rl +creation_date: 2013-06-20T19:41:54Z + +[Term] +id: GO:1902256 +name: regulation of apoptotic process involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] +synonym: "regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +relationship: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +created_by: dph +creation_date: 2013-06-24T19:12:24Z + +[Term] +id: GO:1902257 +name: negative regulation of apoptotic process involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] +synonym: "down regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis +is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +relationship: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +created_by: dph +creation_date: 2013-06-24T19:12:30Z + +[Term] +id: GO:1902258 +name: positive regulation of apoptotic process involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] +synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis +is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +relationship: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis +created_by: dph +creation_date: 2013-06-24T19:12:42Z + +[Term] +id: GO:1902259 +name: regulation of delayed rectifier potassium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11299204] +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005251 ! delayed rectifier potassium channel activity +relationship: regulates GO:0005251 ! delayed rectifier potassium channel activity +created_by: rl +creation_date: 2013-06-25T12:16:19Z + +[Term] +id: GO:1902260 +name: negative regulation of delayed rectifier potassium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11299204] +synonym: "down regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of delayed rectifier potassium channel activity" NARROW [GOC:TermGenie] +is_a: GO:1902259 ! regulation of delayed rectifier potassium channel activity +is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005251 ! delayed rectifier potassium channel activity +relationship: negatively_regulates GO:0005251 ! delayed rectifier potassium channel activity +created_by: rl +creation_date: 2013-06-25T12:16:24Z + +[Term] +id: GO:1902261 +name: positive regulation of delayed rectifier potassium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11299204] +synonym: "activation of delayed rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] +is_a: GO:1902259 ! regulation of delayed rectifier potassium channel activity +is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005251 ! delayed rectifier potassium channel activity +relationship: positively_regulates GO:0005251 ! delayed rectifier potassium channel activity +created_by: rl +creation_date: 2013-06-25T12:16:30Z + +[Term] +id: GO:1902262 +name: apoptotic process involved in blood vessel morphogenesis +namespace: biological_process +def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358] +synonym: "apoptosis involved in patterning of blood vessels" NARROW [GOC:TermGenie] +synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "apoptotic program involved in patterning of blood vessels" NARROW [GOC:TermGenie] +synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity involved in patterning of blood vessels" RELATED [GOC:TermGenie] +synonym: "type I programmed cell death involved in patterning of blood vessels" NARROW [GOC:TermGenie] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0048514 ! blood vessel morphogenesis +relationship: part_of GO:0048514 ! blood vessel morphogenesis +created_by: dph +creation_date: 2013-06-25T16:16:00Z + +[Term] +id: GO:1902263 +name: apoptotic process involved in embryonic digit morphogenesis +namespace: biological_process +def: "Any apoptotic process that is involved in embryonic digit morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:15967824] +synonym: "apoptosis involved in embryonic digit morphogenesis" NARROW [GOC:TermGenie] +synonym: "apoptotic cell death involved in embryonic digit morphogenesis" EXACT [GOC:TermGenie] +synonym: "apoptotic program involved in embryonic digit morphogenesis" NARROW [GOC:TermGenie] +synonym: "apoptotic programmed cell death involved in embryonic digit morphogenesis" EXACT [GOC:TermGenie] +synonym: "programmed cell death by apoptosis involved in embryonic digit morphogenesis" EXACT [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity involved in embryonic digit morphogenesis" RELATED [GOC:TermGenie] +synonym: "type I programmed cell death involved in embryonic digit morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0042733 ! embryonic digit morphogenesis +relationship: part_of GO:0042733 ! embryonic digit morphogenesis +created_by: dph +creation_date: 2013-06-25T16:19:22Z + +[Term] +id: GO:1902265 +name: abscisic acid homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell." [GOC:TermGenie, PMID:23252460] +synonym: "2-cis-abscisate homeostasis" RELATED [] +synonym: "ABA homeostasis" RELATED [] +is_a: GO:0055081 ! anion homeostasis +is_a: GO:0055088 ! lipid homeostasis +created_by: tb +creation_date: 2013-06-27T21:05:30Z + +[Term] +id: GO:1902266 +name: cellular abscisic acid homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell." [GOC:TermGenie, PMID:23252460] +synonym: "cellular 2-cis-abscisate homeostasis" EXACT [] +synonym: "cellular ABA homeostasis" RELATED [] +is_a: GO:0030002 ! cellular anion homeostasis +is_a: GO:1902265 ! abscisic acid homeostasis +created_by: tb +creation_date: 2013-06-27T21:05:36Z + +[Term] +id: GO:1902267 +name: regulation of polyamine transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polyamine transmembrane transport." [GOC:TermGenie, PMID:23755272] +is_a: GO:0034762 ! regulation of transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902047 ! polyamine transmembrane transport +relationship: regulates GO:1902047 ! polyamine transmembrane transport +created_by: mcc +creation_date: 2013-06-28T21:34:36Z + +[Term] +id: GO:1902268 +name: negative regulation of polyamine transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport." [GOC:TermGenie, PMID:23755272] +synonym: "down regulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of polyamine transmembrane transport" NARROW [GOC:TermGenie] +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:1902267 ! regulation of polyamine transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902047 ! polyamine transmembrane transport +relationship: negatively_regulates GO:1902047 ! polyamine transmembrane transport +created_by: mcc +creation_date: 2013-06-28T21:34:42Z + +[Term] +id: GO:1902269 +name: positive regulation of polyamine transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport." [GOC:TermGenie, PMID:23755272] +synonym: "activation of polyamine transmembrane transport" NARROW [GOC:TermGenie] +synonym: "up regulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of polyamine transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:1902267 ! regulation of polyamine transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902047 ! polyamine transmembrane transport +relationship: positively_regulates GO:1902047 ! polyamine transmembrane transport +created_by: mcc +creation_date: 2013-06-28T21:34:47Z + +[Term] +id: GO:1902270 +name: (R)-carnitine transmembrane transport +namespace: biological_process +def: "The process in which (R)-carnitine is transported across a membrane." [GOC:TermGenie, PMID:23755272] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:1900749 ! (R)-carnitine transport +is_a: GO:1902603 ! carnitine transmembrane transport +created_by: mcc +creation_date: 2013-06-28T21:57:39Z + +[Term] +id: GO:1902271 +name: D3 vitamins binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with D3 vitamins." [GOC:bf, GOC:TermGenie, PMID:9127467] +is_a: GO:0005499 ! vitamin D binding +created_by: bf +creation_date: 2013-07-01T12:54:37Z + +[Term] +id: GO:1902272 +name: regulation of (R)-carnitine transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport." [GOC:TermGenie, PMID:23755272] +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902270 ! (R)-carnitine transmembrane transport +relationship: regulates GO:1902270 ! (R)-carnitine transmembrane transport +created_by: mcc +creation_date: 2013-07-01T13:13:11Z + +[Term] +id: GO:1902273 +name: negative regulation of (R)-carnitine transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport." [GOC:TermGenie, PMID:23755272] +synonym: "down regulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of (R)-carnitine transmembrane transport" NARROW [GOC:TermGenie] +is_a: GO:1902272 ! regulation of (R)-carnitine transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902270 ! (R)-carnitine transmembrane transport +relationship: negatively_regulates GO:1902270 ! (R)-carnitine transmembrane transport +created_by: mcc +creation_date: 2013-07-01T13:13:17Z + +[Term] +id: GO:1902274 +name: positive regulation of (R)-carnitine transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport." [GOC:TermGenie, PMID:23755272] +synonym: "activation of (R)-carnitine transmembrane transport" NARROW [GOC:TermGenie] +synonym: "up regulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of (R)-carnitine transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:1902272 ! regulation of (R)-carnitine transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902270 ! (R)-carnitine transmembrane transport +relationship: positively_regulates GO:1902270 ! (R)-carnitine transmembrane transport +created_by: mcc +creation_date: 2013-07-01T13:13:22Z + +[Term] +id: GO:1902275 +name: regulation of chromatin organization +namespace: biological_process +alt_id: GO:1903308 +def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879] +synonym: "regulation of chromatin modification" RELATED [] +synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006325 ! chromatin organization +relationship: regulates GO:0006325 ! chromatin organization +created_by: bf +creation_date: 2013-07-01T13:21:52Z + +[Term] +id: GO:1902276 +name: regulation of pancreatic amylase secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pancreatic amylase secretion." [GOC:jc, GOC:TermGenie] +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0090186 ! regulation of pancreatic juice secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036395 ! pancreatic amylase secretion +relationship: regulates GO:0036395 ! pancreatic amylase secretion +created_by: bf +creation_date: 2013-07-03T12:15:20Z + +[Term] +id: GO:1902277 +name: negative regulation of pancreatic amylase secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion." [GOC:jc, GOC:TermGenie] +synonym: "down regulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of pancreatic amylase secretion" NARROW [GOC:TermGenie] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0090188 ! negative regulation of pancreatic juice secretion +is_a: GO:1902276 ! regulation of pancreatic amylase secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036395 ! pancreatic amylase secretion +relationship: negatively_regulates GO:0036395 ! pancreatic amylase secretion +created_by: bf +creation_date: 2013-07-03T12:15:26Z + +[Term] +id: GO:1902278 +name: positive regulation of pancreatic amylase secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion." [GOC:jc, GOC:TermGenie, PMID:19028687] +synonym: "activation of pancreatic amylase secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic amylase secretion" EXACT [GOC:TermGenie] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0090187 ! positive regulation of pancreatic juice secretion +is_a: GO:1902276 ! regulation of pancreatic amylase secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036395 ! pancreatic amylase secretion +relationship: positively_regulates GO:0036395 ! pancreatic amylase secretion +created_by: bf +creation_date: 2013-07-03T12:15:31Z + +[Term] +id: GO:1902279 +name: positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway +namespace: biological_process +def: "A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion." [GOC:jc, GOC:TermGenie, PMID:19028687] +synonym: "activation of pancreatic amylase secretion by cholecystokinin signaling pathway" NARROW [GOC:TermGenie] +synonym: "CCK-induced amylase release in pancreatic cell" EXACT [PMID:19028687] +synonym: "CCK-mediated pancreatic amylase secretion" EXACT [PMID:19028687] +synonym: "CCK-stimulated pancreatic amylase release" EXACT [PMID:19028687] +synonym: "cholecystokinin-mediated pancreatic amylase secretion" EXACT [PMID:19028687] +synonym: "up regulation of pancreatic amylase secretion by cholecystokinin signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic amylase secretion by cholecystokinin signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic amylase secretion by cholecystokinin signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0038188 ! cholecystokinin signaling pathway +is_a: GO:1902278 ! positive regulation of pancreatic amylase secretion +intersection_of: GO:0038188 ! cholecystokinin signaling pathway +intersection_of: positively_regulates GO:0036395 ! pancreatic amylase secretion +created_by: bf +creation_date: 2013-07-03T16:02:40Z + +[Term] +id: GO:1902280 +name: regulation of RNA helicase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:23721653] +synonym: "regulation of ATP-dependent RNA helicase activity" EXACT [] +is_a: GO:0051095 ! regulation of helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003724 ! RNA helicase activity +relationship: regulates GO:0003724 ! RNA helicase activity +created_by: rb +creation_date: 2013-07-03T18:05:19Z + +[Term] +id: GO:1902281 +name: negative regulation of RNA helicase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:23721653] +synonym: "down regulation of ATP-dependent RNA helicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP-dependent RNA helicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP-dependent RNA helicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ATP-dependent RNA helicase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP-dependent RNA helicase activity" EXACT [] +is_a: GO:0051097 ! negative regulation of helicase activity +is_a: GO:1902280 ! regulation of RNA helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003724 ! RNA helicase activity +relationship: negatively_regulates GO:0003724 ! RNA helicase activity +created_by: rb +creation_date: 2013-07-03T18:05:25Z + +[Term] +id: GO:1902282 +name: voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +namespace: molecular_function +def: "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:8528244] +synonym: "voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0086008 ! voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization +relationship: part_of GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +created_by: rl +creation_date: 2013-07-05T20:12:22Z + +[Term] +id: GO:1902283 +name: negative regulation of primary amine oxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity." [GOC:TermGenie, PMID:23349812] +synonym: "down regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] +synonym: "down regulation of primary amine oxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of primary amine oxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] +synonym: "downregulation of primary amine oxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] +synonym: "inhibition of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of primary amine oxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008131 ! primary amine oxidase activity +relationship: negatively_regulates GO:0008131 ! primary amine oxidase activity +created_by: ecu +creation_date: 2013-07-08T13:27:59Z + +[Term] +id: GO:1902284 +name: neuron projection extension involved in neuron projection guidance +namespace: biological_process +def: "Any neuron projection extension that is involved in neuron projection guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009] +synonym: "neurite extension involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "neurite extension involved in neuron process guidance" NARROW [GOC:TermGenie] +synonym: "neurite extension involved in neuron projection guidance" NARROW [GOC:TermGenie] +synonym: "neurite extension involved in neuron protrusion guidance" NARROW [GOC:TermGenie] +synonym: "neurite extension involved in neuronal cell projection guidance" NARROW [GOC:TermGenie] +synonym: "neuron process extension involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "neuron process extension involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "neuron process extension involved in neuron projection guidance" EXACT [GOC:TermGenie] +synonym: "neuron process extension involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "neuron process extension involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +synonym: "neuron projection extension involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "neuron projection extension involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "neuron projection extension involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "neuron projection extension involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +synonym: "neuron protrusion extension involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "neuron protrusion extension involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "neuron protrusion extension involved in neuron projection guidance" EXACT [GOC:TermGenie] +synonym: "neuron protrusion extension involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "neuron protrusion extension involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +synonym: "neuronal cell projection extension involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "neuronal cell projection extension involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "neuronal cell projection extension involved in neuron projection guidance" EXACT [GOC:TermGenie] +synonym: "neuronal cell projection extension involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "neuronal cell projection extension involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +is_a: GO:1990138 ! neuron projection extension +intersection_of: GO:1990138 ! neuron projection extension +intersection_of: part_of GO:0097485 ! neuron projection guidance +relationship: part_of GO:0097485 ! neuron projection guidance +created_by: pr +creation_date: 2013-07-08T15:55:17Z + +[Term] +id: GO:1902285 +name: semaphorin-plexin signaling pathway involved in neuron projection guidance +namespace: biological_process +def: "Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009] +synonym: "semaphorin-plexin signaling pathway involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in neurite guidance" NARROW [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in neuron process guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in neuron projection guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in neuron protrusion guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in neuronal cell projection guidance" EXACT [GOC:TermGenie] +is_a: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:0097485 ! neuron projection guidance +relationship: part_of GO:0097485 ! neuron projection guidance +created_by: pr +creation_date: 2013-07-08T16:06:46Z + +[Term] +id: GO:1902286 +name: semaphorin-plexin signaling pathway involved in dendrite guidance +namespace: biological_process +def: "Any semaphorin-plexin signaling pathway that is involved in dendrite guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009] +synonym: "semaphorin-plexin signaling pathway involved in dendritic guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in dendrite guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in dendritic guidance" EXACT [GOC:TermGenie] +is_a: GO:1902285 ! semaphorin-plexin signaling pathway involved in neuron projection guidance +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:0070983 ! dendrite guidance +relationship: part_of GO:0070983 ! dendrite guidance +created_by: pr +creation_date: 2013-07-08T16:06:55Z + +[Term] +id: GO:1902287 +name: semaphorin-plexin signaling pathway involved in axon guidance +namespace: biological_process +def: "Any semaphorin-plexin signaling pathway that is involved in axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22790009] +synonym: "semaphorin-plexin signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "semaphorin-plexin signaling pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "semaphorin-plexin signalling pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902285 ! semaphorin-plexin signaling pathway involved in neuron projection guidance +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +created_by: pr +creation_date: 2013-07-08T16:07:03Z + +[Term] +id: GO:1902288 +name: regulation of defense response to oomycetes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to oomycetes." [GOC:TermGenie, PMID:16040633] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002229 ! defense response to oomycetes +relationship: regulates GO:0002229 ! defense response to oomycetes +created_by: ms +creation_date: 2013-07-09T13:45:32Z + +[Term] +id: GO:1902289 +name: negative regulation of defense response to oomycetes +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes." [GOC:TermGenie, PMID:16040633] +synonym: "down regulation of defense response to oomycetes" EXACT [GOC:TermGenie] +synonym: "down-regulation of defense response to oomycetes" EXACT [GOC:TermGenie] +synonym: "downregulation of defense response to oomycetes" EXACT [GOC:TermGenie] +synonym: "inhibition of defense response to oomycetes" NARROW [GOC:TermGenie] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:1902288 ! regulation of defense response to oomycetes +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002229 ! defense response to oomycetes +relationship: negatively_regulates GO:0002229 ! defense response to oomycetes +created_by: ms +creation_date: 2013-07-09T13:45:37Z + +[Term] +id: GO:1902290 +name: positive regulation of defense response to oomycetes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defense response to oomycetes." [GOC:TermGenie, PMID:16040633] +synonym: "activation of defense response to oomycetes" NARROW [GOC:TermGenie] +synonym: "up regulation of defense response to oomycetes" EXACT [GOC:TermGenie] +synonym: "up-regulation of defense response to oomycetes" EXACT [GOC:TermGenie] +synonym: "upregulation of defense response to oomycetes" EXACT [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:1902288 ! regulation of defense response to oomycetes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002229 ! defense response to oomycetes +relationship: positively_regulates GO:0002229 ! defense response to oomycetes +created_by: ms +creation_date: 2013-07-09T13:45:43Z + +[Term] +id: GO:1902291 +name: cell cycle DNA replication DNA ligation +namespace: biological_process +def: "Any DNA ligation that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA ligation involved in cell cycle DNA replication" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0051104 ! DNA-dependent DNA replication DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-09T16:05:45Z + +[Term] +id: GO:1902292 +name: cell cycle DNA replication initiation +namespace: biological_process +def: "Any DNA replication initiation that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA endoreduplication initiation involved in cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA re-replication initiation involved in cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA replication initiation involved in cell cycle DNA replication" EXACT [] +synonym: "DNA-dependent DNA replication initiation involved in cell cycle DNA replication" EXACT [GOC:TermGenie] +is_a: GO:0006270 ! DNA replication initiation +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006270 ! DNA replication initiation +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-09T16:05:54Z + +[Term] +id: GO:1902294 +name: cell cycle DNA replication termination +namespace: biological_process +def: "Any DNA replication termination that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication termination involved in cell cycle DNA replication" EXACT [] +is_a: GO:0006274 ! DNA replication termination +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006274 ! DNA replication termination +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-09T16:06:11Z + +[Term] +id: GO:1902295 +name: synthesis of RNA primer involved in cell cycle DNA replication +namespace: biological_process +def: "Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication, synthesis of RNA primer involved in cell cycle DNA replication" EXACT [] +synonym: "replication priming involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +is_a: GO:0006269 ! DNA replication, synthesis of RNA primer +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006269 ! DNA replication, synthesis of RNA primer +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-09T16:06:26Z + +[Term] +id: GO:1902296 +name: DNA strand elongation involved in cell cycle DNA replication +namespace: biological_process +def: "Any DNA strand elongation that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication elongation involved in cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA strand elongation during DNA replication involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +is_a: GO:0006271 ! DNA strand elongation involved in DNA replication +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006271 ! DNA strand elongation involved in DNA replication +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-10T11:47:02Z + +[Term] +id: GO:1902297 +name: cell cycle DNA replication DNA unwinding +namespace: biological_process +def: "Any DNA unwinding that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA unwinding during replication involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +synonym: "DNA unwinding factor involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +synonym: "DNA unwinding involved in cell cycle DNA replication" EXACT [] +is_a: GO:0006268 ! DNA unwinding involved in DNA replication +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0006268 ! DNA unwinding involved in DNA replication +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-10T11:47:10Z + +[Term] +id: GO:1902298 +name: cell cycle DNA replication maintenance of fidelity +namespace: biological_process +def: "Any maintenance of fidelity that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "maintenance of fidelity during DNA-dependent DNA replication involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +synonym: "maintenance of fidelity involved in cell cycle DNA replication" EXACT [] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +intersection_of: GO:0045005 ! DNA-dependent DNA replication maintenance of fidelity +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-10T11:47:19Z + +[Term] +id: GO:1902299 +name: pre-replicative complex assembly involved in cell cycle DNA replication +namespace: biological_process +def: "Any pre-replicative complex assembly that is involved in cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "pre-RC assembly involved in cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "pre-replication complex assembly involved in cell cycle DNA replication" RELATED [GOC:TermGenie] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0036388 ! pre-replicative complex assembly +intersection_of: GO:0036388 ! pre-replicative complex assembly +intersection_of: part_of GO:0044786 ! cell cycle DNA replication +relationship: part_of GO:0044786 ! cell cycle DNA replication +created_by: jl +creation_date: 2013-07-10T11:47:28Z + +[Term] +id: GO:1902300 +name: galactarate transmembrane transport +namespace: biological_process +alt_id: GO:0042871 +def: "The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +synonym: "D-galactarate transport" RELATED [] +synonym: "galactarate transport" RELATED [] +synonym: "galactaric acid anion transport" EXACT [] +is_a: GO:0042869 ! aldarate transmembrane transport +created_by: pr +creation_date: 2013-07-16T07:11:45Z + +[Term] +id: GO:1902301 +name: galactarate transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0042877 +def: "Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] +synonym: "D-galactarate transmembrane transporter activity" RELATED [] +synonym: "galactaric acid anion transmembrane transporter activity" EXACT [] +is_a: GO:0042876 ! aldarate transmembrane transporter activity +relationship: part_of GO:1902300 ! galactarate transmembrane transport +created_by: pr +creation_date: 2013-07-16T07:26:36Z + +[Term] +id: GO:1902305 +name: regulation of sodium ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] +synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +is_a: GO:0002028 ! regulation of sodium ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035725 ! sodium ion transmembrane transport +relationship: regulates GO:0035725 ! sodium ion transmembrane transport +created_by: rl +creation_date: 2013-07-18T13:33:53Z + +[Term] +id: GO:1902306 +name: negative regulation of sodium ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] +synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +is_a: GO:0010766 ! negative regulation of sodium ion transport +is_a: GO:1902305 ! regulation of sodium ion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035725 ! sodium ion transmembrane transport +relationship: negatively_regulates GO:0035725 ! sodium ion transmembrane transport +created_by: rl +creation_date: 2013-07-18T13:34:01Z + +[Term] +id: GO:1902307 +name: positive regulation of sodium ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] +synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie] +synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:0010765 ! positive regulation of sodium ion transport +is_a: GO:1902305 ! regulation of sodium ion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035725 ! sodium ion transmembrane transport +relationship: positively_regulates GO:0035725 ! sodium ion transmembrane transport +created_by: rl +creation_date: 2013-07-18T13:34:18Z + +[Term] +id: GO:1902308 +name: regulation of peptidyl-serine dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11953308] +is_a: GO:0035304 ! regulation of protein dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070262 ! peptidyl-serine dephosphorylation +relationship: regulates GO:0070262 ! peptidyl-serine dephosphorylation +created_by: rl +creation_date: 2013-07-19T10:34:59Z + +[Term] +id: GO:1902309 +name: negative regulation of peptidyl-serine dephosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11953308] +synonym: "down regulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidyl-serine dephosphorylation" NARROW [GOC:TermGenie] +is_a: GO:0035308 ! negative regulation of protein dephosphorylation +is_a: GO:1902308 ! regulation of peptidyl-serine dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070262 ! peptidyl-serine dephosphorylation +relationship: negatively_regulates GO:0070262 ! peptidyl-serine dephosphorylation +created_by: rl +creation_date: 2013-07-19T10:35:07Z + +[Term] +id: GO:1902310 +name: positive regulation of peptidyl-serine dephosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11953308] +synonym: "activation of peptidyl-serine dephosphorylation" NARROW [GOC:TermGenie] +synonym: "up regulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-serine dephosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0035307 ! positive regulation of protein dephosphorylation +is_a: GO:1902308 ! regulation of peptidyl-serine dephosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070262 ! peptidyl-serine dephosphorylation +relationship: positively_regulates GO:0070262 ! peptidyl-serine dephosphorylation +created_by: rl +creation_date: 2013-07-19T10:35:15Z + +[Term] +id: GO:1902311 +name: regulation of copper ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of copper ion transmembrane transport." [GOC:di, GOC:TermGenie, PMID:21489137] +synonym: "regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +is_a: GO:0010959 ! regulation of metal ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035434 ! copper ion transmembrane transport +relationship: regulates GO:0035434 ! copper ion transmembrane transport +created_by: di +creation_date: 2013-07-19T20:59:28Z + +[Term] +id: GO:1902312 +name: negative regulation of copper ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport." [GOC:di, GOC:TermGenie, PMID:21489137] +synonym: "down regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of copper cation transmembrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of copper ion membrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of copper ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "negative regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +is_a: GO:1902311 ! regulation of copper ion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035434 ! copper ion transmembrane transport +relationship: negatively_regulates GO:0035434 ! copper ion transmembrane transport +created_by: di +creation_date: 2013-07-19T20:59:37Z + +[Term] +id: GO:1902313 +name: positive regulation of copper ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport." [GOC:di, GOC:TermGenie, PMID:21489137] +synonym: "activation of copper cation transmembrane transport" NARROW [GOC:TermGenie] +synonym: "activation of copper ion membrane transport" NARROW [GOC:TermGenie] +synonym: "activation of copper ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of copper cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of copper ion membrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of copper ion transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:1902311 ! regulation of copper ion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035434 ! copper ion transmembrane transport +relationship: positively_regulates GO:0035434 ! copper ion transmembrane transport +created_by: di +creation_date: 2013-07-19T20:59:45Z + +[Term] +id: GO:1902314 +name: hydroquinone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with hydroquinone." [GOC:bhm, GOC:TermGenie, pmid:15667223] +synonym: "quinol binding" EXACT [] +is_a: GO:0048037 ! cofactor binding +is_a: GO:0097159 ! organic cyclic compound binding +created_by: bhm +creation_date: 2013-07-22T10:10:12Z + +[Term] +id: GO:1902315 +name: nuclear cell cycle DNA replication initiation +namespace: biological_process +def: "Any DNA replication initiation that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA endoreduplication initiation involved in nuclear cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA re-replication initiation involved in nuclear cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA replication initiation involved in nuclear cell cycle DNA replication" EXACT [] +is_a: GO:1902292 ! cell cycle DNA replication initiation +intersection_of: GO:0006270 ! DNA replication initiation +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-23T14:00:01Z + +[Term] +id: GO:1902317 +name: nuclear DNA replication termination +namespace: biological_process +def: "Any DNA replication termination that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication termination involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA replication termination involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA replication termination involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "DNA replication termination involved in nuclear cell cycle DNA replication" EXACT [] +is_a: GO:1902294 ! cell cycle DNA replication termination +intersection_of: GO:0006274 ! DNA replication termination +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-23T14:00:17Z + +[Term] +id: GO:1902318 +name: synthesis of RNA primer involved in nuclear cell cycle DNA replication +namespace: biological_process +def: "Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication, synthesis of RNA primer involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA replication, synthesis of RNA primer involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA replication, synthesis of RNA primer involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "replication priming involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "replication priming involved in DNA replication involved in S phase" RELATED [GOC:TermGenie] +synonym: "replication priming involved in DNA replication involved in S-phase" RELATED [GOC:TermGenie] +synonym: "replication priming involved in nuclear cell cycle DNA replication" RELATED [GOC:TermGenie] +is_a: GO:1902295 ! synthesis of RNA primer involved in cell cycle DNA replication +intersection_of: GO:0006269 ! DNA replication, synthesis of RNA primer +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-23T14:00:33Z + +[Term] +id: GO:1902319 +name: DNA strand elongation involved in nuclear cell cycle DNA replication +namespace: biological_process +def: "Any DNA strand elongation that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA strand elongation involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA strand elongation involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA strand elongation involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +is_a: GO:1902296 ! DNA strand elongation involved in cell cycle DNA replication +intersection_of: GO:0022616 ! DNA strand elongation +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-23T14:00:41Z + +[Term] +id: GO:1902320 +name: nuclear DNA replication DNA duplex unwinding +namespace: biological_process +def: "Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA duplex unwinding involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA duplex unwinding involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA duplex unwinding involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "DNA duplex unwinding involved in nuclear cell cycle DNA replication" EXACT [] +synonym: "DNA unwinding involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA unwinding involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA unwinding involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "DNA unwinding involved in nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "duplex DNA melting involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "duplex DNA melting involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "duplex DNA melting involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +is_a: GO:1902297 ! cell cycle DNA replication DNA unwinding +intersection_of: GO:0032508 ! DNA duplex unwinding +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-23T14:00:49Z + +[Term] +id: GO:1902321 +name: methyl-branched fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid." [GOC:kmv, GOC:TermGenie, PMID:15340492] +synonym: "methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006633 ! fatty acid biosynthetic process +is_a: GO:0097089 ! methyl-branched fatty acid metabolic process +created_by: kmv +creation_date: 2013-07-23T20:40:46Z + +[Term] +id: GO:1902322 +name: regulation of methyl-branched fatty acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process." [GOC:kmv, GOC:TermGenie, PMID:15340492] +synonym: "regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +relationship: regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +created_by: kmv +creation_date: 2013-07-24T20:15:15Z + +[Term] +id: GO:1902323 +name: negative regulation of methyl-branched fatty acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process." [GOC:kmv, GOC:TermGenie, PMID:15340492] +synonym: "down regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of methyl-branched fatty acid anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of methyl-branched fatty acid biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of methyl-branched fatty acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of methyl-branched fatty acid formation" NARROW [GOC:TermGenie] +synonym: "inhibition of methyl-branched fatty acid synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0045717 ! negative regulation of fatty acid biosynthetic process +is_a: GO:1902322 ! regulation of methyl-branched fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +relationship: negatively_regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +created_by: kmv +creation_date: 2013-07-24T20:15:23Z + +[Term] +id: GO:1902324 +name: positive regulation of methyl-branched fatty acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process." [GOC:kmv, GOC:TermGenie, PMID:15340492] +synonym: "activation of methyl-branched fatty acid anabolism" NARROW [GOC:TermGenie] +synonym: "activation of methyl-branched fatty acid biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of methyl-branched fatty acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of methyl-branched fatty acid formation" NARROW [GOC:TermGenie] +synonym: "activation of methyl-branched fatty acid synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of methyl-branched fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of methyl-branched fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of methyl-branched fatty acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of methyl-branched fatty acid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of methyl-branched fatty acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process +is_a: GO:1902322 ! regulation of methyl-branched fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +relationship: positively_regulates GO:1902321 ! methyl-branched fatty acid biosynthetic process +created_by: kmv +creation_date: 2013-07-24T20:15:31Z + +[Term] +id: GO:1902325 +name: negative regulation of chlorophyll biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process." [GOC:TermGenie, PMID:23555952] +synonym: "down regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chlorophyll anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll formation" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010380 ! regulation of chlorophyll biosynthetic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1901464 ! negative regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015995 ! chlorophyll biosynthetic process +relationship: negatively_regulates GO:0015995 ! chlorophyll biosynthetic process +created_by: tb +creation_date: 2013-07-24T22:47:29Z + +[Term] +id: GO:1902326 +name: positive regulation of chlorophyll biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process." [GOC:TermGenie, PMID:23555952] +synonym: "activation of chlorophyll anabolism" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll formation" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll formation" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010380 ! regulation of chlorophyll biosynthetic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1901465 ! positive regulation of tetrapyrrole biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015995 ! chlorophyll biosynthetic process +relationship: positively_regulates GO:0015995 ! chlorophyll biosynthetic process +created_by: tb +creation_date: 2013-07-24T22:47:37Z + +[Term] +id: GO:1902327 +name: bacterial-type DNA replication DNA ligation +namespace: biological_process +def: "Any DNA ligation that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA ligation involved in bacterial-type DNA replication" EXACT [] +is_a: GO:1902291 ! cell cycle DNA replication DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0044787 ! bacterial-type DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: jl +creation_date: 2013-07-25T10:47:46Z + +[Term] +id: GO:1902328 +name: bacterial-type DNA replication initiation +namespace: biological_process +def: "Any DNA replication initiation that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA endoreduplication initiation involved in bacterial-type DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA re-replication initiation involved in bacterial-type DNA replication" NARROW [GOC:TermGenie] +synonym: "DNA replication initiation involved in bacterial-type DNA replication" EXACT [] +synonym: "DNA-dependent DNA replication initiation involved in bacterial-type DNA replication" EXACT [GOC:TermGenie] +is_a: GO:1902292 ! cell cycle DNA replication initiation +intersection_of: GO:0006270 ! DNA replication initiation +intersection_of: part_of GO:0044787 ! bacterial-type DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: jl +creation_date: 2013-07-25T10:48:02Z + +[Term] +id: GO:1902329 +name: bacterial-type DNA replication termination +namespace: biological_process +def: "Any DNA replication termination that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA replication termination involved in bacterial-type DNA replication" EXACT [] +is_a: GO:1902294 ! cell cycle DNA replication termination +intersection_of: GO:0006274 ! DNA replication termination +intersection_of: part_of GO:0044787 ! bacterial-type DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: jl +creation_date: 2013-07-25T10:48:10Z + +[Term] +id: GO:1902330 +name: synthesis of RNA primer involved in bacterial-type DNA replication +namespace: biological_process +def: "Any synthesis of RNA primer that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "replication priming involved in bacterial-type DNA replication" RELATED [GOC:TermGenie] +is_a: GO:1902295 ! synthesis of RNA primer involved in cell cycle DNA replication +intersection_of: GO:0006269 ! DNA replication, synthesis of RNA primer +intersection_of: part_of GO:0044787 ! bacterial-type DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: jl +creation_date: 2013-07-25T10:48:18Z + +[Term] +id: GO:1902331 +name: obsolete DNA strand elongation involved in bacterial-type DNA replication +namespace: biological_process +def: "OBSOLETE. Any DNA strand elongation that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +comment: This term was obsoleted because it does not represent a distinct function from its parent, DNA strand elongation involved in DNA replication. +is_obsolete: true +created_by: jl +creation_date: 2013-07-25T10:48:26Z + +[Term] +id: GO:1902332 +name: bacterial-type DNA replication DNA duplex unwinding +namespace: biological_process +def: "Any DNA duplex unwinding that is involved in bacterial-type DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA duplex unwinding involved in bacterial-type DNA replication" EXACT [] +synonym: "DNA unwinding involved in bacterial-type DNA replication" EXACT [GOC:TermGenie] +synonym: "duplex DNA melting involved in bacterial-type DNA replication" EXACT [GOC:TermGenie] +is_a: GO:1902297 ! cell cycle DNA replication DNA unwinding +intersection_of: GO:0032508 ! DNA duplex unwinding +intersection_of: part_of GO:0044787 ! bacterial-type DNA replication +relationship: part_of GO:0044787 ! bacterial-type DNA replication +created_by: jl +creation_date: 2013-07-25T10:48:34Z + +[Term] +id: GO:1902333 +name: nuclear DNA replication DNA ligation +namespace: biological_process +def: "Any DNA ligation that is involved in nuclear cell cycle DNA replication." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "DNA ligation involved in DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "DNA ligation involved in DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "DNA ligation involved in DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "DNA ligation involved in nuclear cell cycle DNA replication" EXACT [] +is_a: GO:1902291 ! cell cycle DNA replication DNA ligation +intersection_of: GO:0006266 ! DNA ligation +intersection_of: part_of GO:0033260 ! nuclear DNA replication +relationship: part_of GO:0033260 ! nuclear DNA replication +created_by: jl +creation_date: 2013-07-25T10:55:56Z + +[Term] +id: GO:1902334 +name: fructose export from vacuole to cytoplasm +namespace: biological_process +def: "The directed movement of fructose from vacuole to cytoplasm." [GOC:TermGenie, PMID:23583552] +synonym: "fructose transport from vacuole to cytoplasm" EXACT [] +is_a: GO:0015755 ! fructose transmembrane transport +is_a: GO:0033231 ! carbohydrate export +is_a: GO:0034486 ! vacuolar transmembrane transport +created_by: tb +creation_date: 2013-07-26T22:18:12Z + +[Term] +id: GO:1902335 +name: obsolete positive chemotaxis involved in neuron migration +namespace: biological_process +def: "OBSOLETE. Any positive chemotaxis that is involved in neuron migration." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "chemoattraction involved in neuron chemotaxis" EXACT [GOC:TermGenie] +synonym: "chemoattraction involved in neuron guidance" RELATED [GOC:TermGenie] +synonym: "chemoattraction involved in neuron migration" EXACT [GOC:TermGenie] +synonym: "chemoattraction involved in neuronal migration" EXACT [GOC:TermGenie] +synonym: "positive chemotaxis involved in neuron chemotaxis" EXACT [GOC:TermGenie] +synonym: "positive chemotaxis involved in neuron guidance" RELATED [GOC:TermGenie] +synonym: "positive chemotaxis involved in neuron migration" EXACT [] +synonym: "positive chemotaxis involved in neuronal migration" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rl +creation_date: 2013-07-29T12:52:01Z + +[Term] +id: GO:1902336 +name: positive regulation of retinal ganglion cell axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587] +synonym: "activation of retinal ganglion cell axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of retinal ganglion cell axon pathfinding" NARROW [GOC:TermGenie] +synonym: "positive regulation of retinal ganglion cell axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of retinal ganglion cell axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of retinal ganglion cell axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinal ganglion cell axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinal ganglion cell axon pathfinding" EXACT [GOC:TermGenie] +synonym: "upregulation of retinal ganglion cell axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of retinal ganglion cell axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:0090259 ! regulation of retinal ganglion cell axon guidance +is_a: GO:1902669 ! positive regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031290 ! retinal ganglion cell axon guidance +relationship: positively_regulates GO:0031290 ! retinal ganglion cell axon guidance +created_by: rl +creation_date: 2013-07-29T13:02:25Z + +[Term] +id: GO:1902337 +name: regulation of apoptotic process involved in morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] +synonym: "regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060561 ! apoptotic process involved in morphogenesis +relationship: regulates GO:0060561 ! apoptotic process involved in morphogenesis +created_by: sart +creation_date: 2013-07-29T15:03:16Z + +[Term] +id: GO:1902338 +name: negative regulation of apoptotic process involved in morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] +synonym: "down regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "down regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "down-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "downregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "inhibition of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "negative regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis +is_a: GO:1904746 ! negative regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis +relationship: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis +created_by: sart +creation_date: 2013-07-29T15:03:25Z + +[Term] +id: GO:1902339 +name: positive regulation of apoptotic process involved in morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] +synonym: "activation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "activation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "positive regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "up regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "up-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +synonym: "upregulation of apoptosis involved in development" RELATED [GOC:TermGenie] +synonym: "upregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] +is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis +is_a: GO:1904747 ! positive regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis +relationship: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis +created_by: sart +creation_date: 2013-07-29T15:03:33Z + +[Term] +id: GO:1902340 +name: negative regulation of chromosome condensation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725] +synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "inhibition of chromosome condensation" NARROW [GOC:TermGenie] +synonym: "inhibition of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear chromosome condensation" NARROW [GOC:TermGenie] +synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +is_a: GO:0060623 ! regulation of chromosome condensation +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030261 ! chromosome condensation +relationship: negatively_regulates GO:0030261 ! chromosome condensation +created_by: dgf +creation_date: 2013-07-29T20:54:14Z + +[Term] +id: GO:1902341 +name: xylitol transport +namespace: biological_process +def: "The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose." [GOC:TermGenie, PMID:23475614] +is_a: GO:0008643 ! carbohydrate transport +is_a: GO:0015791 ! polyol transport +created_by: se +creation_date: 2013-07-30T16:04:38Z + +[Term] +id: GO:1902342 +name: xylitol export +namespace: biological_process +def: "The directed movement of xylitol out of a cell or organelle." [GOC:TermGenie, PMID:23475614] +is_a: GO:0033231 ! carbohydrate export +is_a: GO:1902341 ! xylitol transport +created_by: se +creation_date: 2013-07-30T16:09:55Z + +[Term] +id: GO:1902343 +name: regulation of maltose transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maltose transport." [GOC:dph, GOC:TermGenie, PMID:23770568] +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015768 ! maltose transport +relationship: regulates GO:0015768 ! maltose transport +created_by: dph +creation_date: 2013-08-01T17:16:18Z + +[Term] +id: GO:1902344 +name: negative regulation of maltose transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport." [GOC:dph, GOC:TermGenie, PMID:23770568] +synonym: "down regulation of maltose transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of maltose transport" EXACT [GOC:TermGenie] +synonym: "downregulation of maltose transport" EXACT [GOC:TermGenie] +synonym: "inhibition of maltose transport" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1902343 ! regulation of maltose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015768 ! maltose transport +relationship: negatively_regulates GO:0015768 ! maltose transport +created_by: dph +creation_date: 2013-08-01T17:16:26Z + +[Term] +id: GO:1902345 +name: positive regulation of maltose transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maltose transport." [GOC:dph, GOC:TermGenie, PMID:23770568] +synonym: "activation of maltose transport" NARROW [GOC:TermGenie] +synonym: "up regulation of maltose transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of maltose transport" EXACT [GOC:TermGenie] +synonym: "upregulation of maltose transport" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1902343 ! regulation of maltose transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015768 ! maltose transport +relationship: positively_regulates GO:0015768 ! maltose transport +created_by: dph +creation_date: 2013-08-01T17:16:34Z + +[Term] +id: GO:1902346 +name: meiotic strand displacement involved in double-strand break repair via SDSA +namespace: biological_process +def: "Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA)." [GOC:al, GOC:TermGenie, PMID:22723423] +synonym: "meiotic D-loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing" RELATED [GOC:TermGenie] +synonym: "meiotic D-loop dissociation involved in mitotic gene conversion" RELATED [GOC:TermGenie] +synonym: "meiotic D-loop processing involved in double-strand break repair via synthesis-dependent strand annealing" RELATED [GOC:TermGenie] +synonym: "meiotic D-loop processing involved in mitotic gene conversion" RELATED [GOC:TermGenie] +synonym: "meiotic displacement loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing" RELATED [GOC:TermGenie] +synonym: "meiotic displacement loop dissociation involved in mitotic gene conversion" RELATED [GOC:TermGenie] +synonym: "meiotic displacement loop processing involved in double-strand break repair via synthesis-dependent strand annealing" RELATED [GOC:TermGenie] +synonym: "meiotic displacement loop processing involved in mitotic gene conversion" RELATED [GOC:TermGenie] +synonym: "meiotic strand displacement involved in double-strand break repair via synthesis-dependent strand annealing" EXACT [] +synonym: "meiotic strand displacement involved in mitotic gene conversion" RELATED [GOC:TermGenie] +synonym: "meiotic strand displacement involved in SDSA" BROAD [] +is_a: GO:0000714 ! meiotic strand displacement +intersection_of: GO:0000714 ! meiotic strand displacement +intersection_of: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing +relationship: part_of GO:0045003 ! double-strand break repair via synthesis-dependent strand annealing +created_by: pr +creation_date: 2013-08-07T12:56:20Z + +[Term] +id: GO:1902347 +name: response to strigolactone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus." [GOC:TermGenie, PMID:23893171] +synonym: "response to strigolactone analog GR24" RELATED [PMID:23893171] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: dhl +creation_date: 2013-08-08T18:44:57Z + +[Term] +id: GO:1902348 +name: cellular response to strigolactone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus." [GOC:TermGenie, PMID:23893171] +synonym: "cellular response to strigolactone analog GR24" RELATED [PMID:23893171] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902347 ! response to strigolactone +created_by: dhl +creation_date: 2013-08-08T18:45:05Z + +[Term] +id: GO:1902349 +name: response to chloroquine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus." [GOC:kmv, GOC:TermGenie, PMID:23922869] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +created_by: kmv +creation_date: 2013-08-13T19:29:25Z + +[Term] +id: GO:1902350 +name: cellular response to chloroquine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus." [GOC:kmv, GOC:TermGenie, PMID:23922869] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1902349 ! response to chloroquine +created_by: kmv +creation_date: 2013-08-13T19:29:33Z + +[Term] +id: GO:1902351 +name: response to imidacloprid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus." [GOC:kmv, GOC:TermGenie, PMID:23922869] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0017085 ! response to insecticide +is_a: GO:0042493 ! response to drug +created_by: kmv +creation_date: 2013-08-13T19:33:15Z + +[Term] +id: GO:1902352 +name: obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation." [GOC:rn, GOC:TermGenie, PMID:23223039] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: bf +creation_date: 2013-08-14T09:35:43Z + +[Term] +id: GO:1902353 +name: obsolete positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion." [GOC:rn, GOC:TermGenie, PMID:23872066] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "up regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GOC:TermGenie] +synonym: "up-regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GOC:TermGenie] +synonym: "upregulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bf +creation_date: 2013-08-14T09:45:21Z + +[Term] +id: GO:1902354 +name: blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment +namespace: biological_process +def: "Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment." [GOC:dgh, GOC:TermGenie, PMID:23698350] +is_a: GO:0097497 ! blood vessel endothelial cell delamination +intersection_of: GO:0097497 ! blood vessel endothelial cell delamination +intersection_of: part_of GO:0097496 ! blood vessel lumen ensheathment +relationship: part_of GO:0097496 ! blood vessel lumen ensheathment +created_by: pr +creation_date: 2013-08-14T10:22:00Z + +[Term] +id: GO:1902355 +name: endothelial tube lumen extension involved in blood vessel lumen ensheathment +namespace: biological_process +def: "Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment." [GOC:dgh, GOC:TermGenie, PMID:23698350] +is_a: GO:0097498 ! endothelial tube lumen extension +intersection_of: GO:0097498 ! endothelial tube lumen extension +intersection_of: part_of GO:0097496 ! blood vessel lumen ensheathment +relationship: part_of GO:0097496 ! blood vessel lumen ensheathment +created_by: pr +creation_date: 2013-08-14T10:22:09Z + +[Term] +id: GO:1902356 +name: oxaloacetate(2-) transmembrane transport +namespace: biological_process +def: "The directed movement of oxaloacetate(2-) across a membrane." [GOC:dph, GOC:TermGenie, PMID:18682385] +is_a: GO:0015729 ! oxaloacetate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: dph +creation_date: 2013-08-14T14:40:37Z + +[Term] +id: GO:1902357 +name: 2-isopropylmalate(2-) transmembrane transport +namespace: biological_process +def: "The process in which 2-isopropylmalate(2-) is transported across a membrane." [GOC:dph, GOC:TermGenie, GOC:vw, PMID:18682385] +is_a: GO:0034659 ! isopropylmalate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: dph +creation_date: 2013-08-14T14:43:49Z + +[Term] +id: GO:1902358 +name: sulfate transmembrane transport +namespace: biological_process +def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] +is_a: GO:0008272 ! sulfate transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: dph +creation_date: 2013-08-14T14:46:04Z + +[Term] +id: GO:1902359 +name: Notch signaling pathway involved in somitogenesis +namespace: biological_process +def: "Any Notch signaling pathway that is involved in somitogenesis." [GOC:dph, GOC:TermGenie, PMID:21795391] +synonym: "N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:0001756 ! somitogenesis +relationship: part_of GO:0001756 ! somitogenesis +created_by: dph +creation_date: 2013-08-14T17:31:43Z + +[Term] +id: GO:1902360 +name: conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA +namespace: biological_process +def: "Any conversion of ds siRNA to ss siRNA that is involved in chromatin silencing by small RNA." [GOC:TermGenie, GOC:vw, PMID:19239886] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in chromatin silencing by small RNA" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA interference-like chromatin silencing" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated chromatin silencing" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated transcriptional silencing" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-directed chromatin silencing" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-like chromatin silencing" RELATED [GOC:TermGenie] +synonym: "conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in small RNA-mediated heterochromatic silencing" RELATED [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in RNA interference-like chromatin silencing" EXACT [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in RNA-mediated chromatin silencing" EXACT [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in RNA-mediated transcriptional silencing" EXACT [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in RNAi-directed chromatin silencing" EXACT [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in RNAi-like chromatin silencing" EXACT [GOC:TermGenie] +synonym: "conversion of ds siRNA to ss siRNA involved in small RNA-mediated heterochromatic silencing" EXACT [GOC:TermGenie] +is_a: GO:0036404 ! conversion of ds siRNA to ss siRNA +intersection_of: GO:0036404 ! conversion of ds siRNA to ss siRNA +intersection_of: part_of GO:0031048 ! heterochromatin assembly by small RNA +relationship: part_of GO:0031048 ! heterochromatin assembly by small RNA +created_by: bf +creation_date: 2013-08-15T10:06:18Z + +[Term] +id: GO:1902362 +name: melanocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a melanocyte, the main structural component of the epidermis." [GOC:ic, GOC:TermGenie, PMID:20530876] +synonym: "melanocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "melanophore apoptosis" NARROW [GOC:TermGenie] +synonym: "melanophore apoptotic process" NARROW [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2013-08-15T16:35:45Z + +[Term] +id: GO:1902363 +name: regulation of protein localization to spindle pole body +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to spindle pole body." [GOC:TermGenie, PMID:21131906] +synonym: "regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071988 ! protein localization to spindle pole body +relationship: regulates GO:0071988 ! protein localization to spindle pole body +created_by: vw +creation_date: 2013-08-15T16:38:07Z + +[Term] +id: GO:1902364 +name: negative regulation of protein localization to spindle pole body +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body." [GOC:TermGenie, PMID:21131906] +synonym: "down regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to spindle pole body" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to spindle pole body" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:1902363 ! regulation of protein localization to spindle pole body +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071988 ! protein localization to spindle pole body +relationship: negatively_regulates GO:0071988 ! protein localization to spindle pole body +created_by: vw +creation_date: 2013-08-15T16:38:23Z + +[Term] +id: GO:1902365 +name: positive regulation of protein localization to spindle pole body +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body." [GOC:TermGenie, PMID:21131906] +synonym: "activation of protein localisation to spindle pole body" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to spindle pole body" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to spindle pole body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:1902363 ! regulation of protein localization to spindle pole body +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071988 ! protein localization to spindle pole body +relationship: positively_regulates GO:0071988 ! protein localization to spindle pole body +created_by: vw +creation_date: 2013-08-15T16:38:31Z + +[Term] +id: GO:1902366 +name: regulation of Notch signaling pathway involved in somitogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis." [GOC:dph, GOC:TermGenie, PMID:21795391] +synonym: "regulation of N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "regulation of Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +is_a: GO:0008593 ! regulation of Notch signaling pathway +is_a: GO:0014807 ! regulation of somitogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902359 ! Notch signaling pathway involved in somitogenesis +relationship: regulates GO:1902359 ! Notch signaling pathway involved in somitogenesis +created_by: dph +creation_date: 2013-08-20T18:24:23Z + +[Term] +id: GO:1902367 +name: negative regulation of Notch signaling pathway involved in somitogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis." [GOC:dph, GOC:TermGenie, PMID:21795391] +synonym: "down regulation of N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down regulation of Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "down-regulation of Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "downregulation of Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of N signaling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of N signaling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of N signalling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of N signalling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch receptor signaling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch receptor signaling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch receptor signalling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch receptor signalling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch signaling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch signaling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch signalling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch signalling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch-receptor signaling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch-receptor signaling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch-receptor signalling pathway involved in formation of mesodermal clusters" NARROW [GOC:TermGenie] +synonym: "inhibition of Notch-receptor signalling pathway involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of N signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of N signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of N signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of N signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch-receptor signaling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters" EXACT [GOC:TermGenie] +synonym: "negative regulation of Notch-receptor signalling pathway involved in somitogenesis" EXACT [GOC:TermGenie] +is_a: GO:0045746 ! negative regulation of Notch signaling pathway +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1902366 ! regulation of Notch signaling pathway involved in somitogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902359 ! Notch signaling pathway involved in somitogenesis +relationship: negatively_regulates GO:1902359 ! Notch signaling pathway involved in somitogenesis +created_by: dph +creation_date: 2013-08-20T18:27:20Z + +[Term] +id: GO:1902369 +name: negative regulation of RNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457] +synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0051253 ! negative regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006401 ! RNA catabolic process +relationship: negatively_regulates GO:0006401 ! RNA catabolic process +created_by: bf +creation_date: 2013-08-22T14:59:39Z + +[Term] +id: GO:1902370 +name: regulation of tRNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie] +synonym: "regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of tRNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:1903326 ! regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016078 ! tRNA catabolic process +relationship: regulates GO:0016078 ! tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:08:12Z + +[Term] +id: GO:1902371 +name: negative regulation of tRNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:22919049] +synonym: "down regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of tRNA breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of tRNA catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tRNA catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of tRNA degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of tRNA degradation" EXACT [GOC:TermGenie] +is_a: GO:1902369 ! negative regulation of RNA catabolic process +is_a: GO:1902370 ! regulation of tRNA catabolic process +is_a: GO:1903327 ! negative regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016078 ! tRNA catabolic process +relationship: negatively_regulates GO:0016078 ! tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:08:20Z + +[Term] +id: GO:1902372 +name: positive regulation of tRNA catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA catabolic process." [GOC:bf, GOC:TermGenie] +synonym: "activation of tRNA breakdown" NARROW [GOC:TermGenie] +synonym: "activation of tRNA catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tRNA catabolism" NARROW [GOC:TermGenie] +synonym: "activation of tRNA degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:1902370 ! regulation of tRNA catabolic process +is_a: GO:1903328 ! positive regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016078 ! tRNA catabolic process +relationship: positively_regulates GO:0016078 ! tRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:08:29Z + +[Term] +id: GO:1902373 +name: negative regulation of mRNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:22626865] +synonym: "down regulation of mRNA breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA decay" RELATED [GOC:TermGenie] +synonym: "down regulation of mRNA degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA decay" RELATED [GOC:TermGenie] +synonym: "down-regulation of mRNA degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA decay" RELATED [GOC:TermGenie] +synonym: "downregulation of mRNA degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of mRNA breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA decay" RELATED [GOC:TermGenie] +synonym: "inhibition of mRNA degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of mRNA breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA decay" RELATED [GOC:TermGenie] +synonym: "negative regulation of mRNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0061013 ! regulation of mRNA catabolic process +is_a: GO:1902369 ! negative regulation of RNA catabolic process +is_a: GO:1903312 ! negative regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006402 ! mRNA catabolic process +relationship: negatively_regulates GO:0006402 ! mRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:16:19Z + +[Term] +id: GO:1902374 +name: regulation of rRNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of rRNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:20160119] +synonym: "regulation of rRNA breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of rRNA catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of rRNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016075 ! rRNA catabolic process +relationship: regulates GO:0016075 ! rRNA catabolic process +created_by: bf +creation_date: 2013-08-22T15:20:59Z + +[Term] +id: GO:1902375 +name: nuclear tRNA 3'-trailer cleavage, endonucleolytic +namespace: biological_process +def: "Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus." [GOC:TermGenie, PMID:23928301] +synonym: "endonucleolytic tRNA 3'-end cleavage in cell nucleus" EXACT [GOC:TermGenie] +synonym: "endonucleolytic tRNA 3'-end cleavage in nucleus" EXACT [GOC:TermGenie] +synonym: "endonucleolytic tRNA 3'-trailer cleavage in cell nucleus" RELATED [GOC:TermGenie] +synonym: "endonucleolytic tRNA 3'-trailer cleavage in nucleus" RELATED [GOC:TermGenie] +synonym: "tRNA 3'-end cleavage, endonucleolytic in cell nucleus" EXACT [GOC:TermGenie] +synonym: "tRNA 3'-end cleavage, endonucleolytic in nucleus" EXACT [GOC:TermGenie] +synonym: "tRNA 3'-trailer cleavage, endonucleolytic in cell nucleus" EXACT [GOC:TermGenie] +is_a: GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic +intersection_of: GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic +intersection_of: occurs_in GO:0005634 ! nucleus +relationship: occurs_in GO:0005634 ! nucleus +created_by: al +creation_date: 2013-08-30T09:17:30Z + +[Term] +id: GO:1902376 +name: obsolete protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "OBSOLETE. Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process." [GOC:TermGenie, PMID:21091378] +comment: This term was made obsolete because it was poorly defined and the intended usage was unclear. +synonym: "protein denaturation involved in proteasomal pathway" EXACT [GOC:TermGenie] +synonym: "protein denaturation involved in proteasomal processing" RELATED [GOC:TermGenie] +synonym: "protein denaturation involved in proteasomal ubiquitin-dependent protein breakdown" EXACT [GOC:TermGenie] +synonym: "protein denaturation involved in proteasomal ubiquitin-dependent protein catabolism" EXACT [GOC:TermGenie] +synonym: "protein denaturation involved in proteasomal ubiquitin-dependent protein degradation" EXACT [GOC:TermGenie] +synonym: "protein denaturation involved in proteasome pathway" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2013-08-30T09:29:14Z + +[Term] +id: GO:1902377 +name: nuclear rDNA heterochromatin +namespace: cellular_component +def: "Any rDNA heterochromatin that is part of a nucleus." [GOC:TermGenie, PMID:20661445] +synonym: "rDNA heterochromatin of cell nucleus" EXACT [GOC:TermGenie] +synonym: "rDNA heterochromatin of nucleus" EXACT [GOC:TermGenie] +synonym: "ribosomal DNA heterochromatin of cell nucleus" EXACT [GOC:TermGenie] +synonym: "ribosomal DNA heterochromatin of nucleus" EXACT [GOC:TermGenie] +is_a: GO:0005720 ! nuclear heterochromatin +is_a: GO:0033553 ! rDNA heterochromatin +intersection_of: GO:0033553 ! rDNA heterochromatin +intersection_of: part_of GO:0005634 ! nucleus +created_by: al +creation_date: 2013-08-30T09:59:42Z + +[Term] +id: GO:1902378 +name: VEGF-activated neuropilin signaling pathway involved in axon guidance +namespace: biological_process +def: "Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587] +synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance" RELATED [GOC:TermGenie] +synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance" RELATED [GOC:TermGenie] +synonym: "vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon pathfinding" RELATED [GOC:TermGenie] +synonym: "VEGF-activated neuropilin signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "VEGF-activated neuropilin signaling pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "VEGF-activated neuropilin signaling pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "VEGF-Npn-1 signaling involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "VEGF-Npn-1 signaling involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "VEGF-Npn-1 signaling involved in axon guidance" NARROW [GOC:TermGenie] +synonym: "VEGF-Npn-1 signaling involved in axon pathfinding" NARROW [GOC:TermGenie] +is_a: GO:0038190 ! VEGF-activated neuropilin signaling pathway +intersection_of: GO:0038190 ! VEGF-activated neuropilin signaling pathway +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +created_by: bf +creation_date: 2013-09-02T13:44:13Z + +[Term] +id: GO:1902379 +name: chemoattractant activity involved in axon guidance +namespace: molecular_function +def: "Any chemoattractant activity that is involved in axon guidance." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21658587] +synonym: "chemoattractant activity involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "chemoattractant activity involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "chemoattractant activity involved in axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:0042056 ! chemoattractant activity +intersection_of: GO:0042056 ! chemoattractant activity +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0061642 ! chemoattraction of axon +created_by: bf +creation_date: 2013-09-02T13:49:35Z + +[Term] +id: GO:1902380 +name: positive regulation of endoribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endoribonuclease activity." [GOC:bf, GOC:TermGenie] +synonym: "activation of endonuclease G activity" RELATED [GOC:TermGenie] +synonym: "activation of endoribonuclease activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of endonuclease G activity" RELATED [GOC:TermGenie] +synonym: "up regulation of endonuclease G activity" RELATED [GOC:TermGenie] +synonym: "up regulation of endoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of endonuclease G activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of endoribonuclease activity" EXACT [GOC:TermGenie] +synonym: "upregulation of endonuclease G activity" RELATED [GOC:TermGenie] +synonym: "upregulation of endoribonuclease activity" EXACT [GOC:TermGenie] +is_a: GO:0032075 ! positive regulation of nuclease activity +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:0060699 ! regulation of endoribonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004521 ! endoribonuclease activity +relationship: positively_regulates GO:0004521 ! endoribonuclease activity +created_by: bf +creation_date: 2013-09-02T14:14:29Z + +[Term] +id: GO:1902381 +name: 11-oxo-beta-amyrin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 11-oxo-beta-amyrin." [GOC:TermGenie, pmid:22128119] +synonym: "11-oxo-beta-amyrin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019742 ! pentacyclic triterpenoid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +created_by: ms +creation_date: 2013-09-03T12:55:29Z + +[Term] +id: GO:1902382 +name: 11-oxo-beta-amyrin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin." [GOC:TermGenie, pmid:22128119] +synonym: "11-oxo-beta-amyrin breakdown" EXACT [GOC:TermGenie] +synonym: "11-oxo-beta-amyrin catabolism" EXACT [GOC:TermGenie] +synonym: "11-oxo-beta-amyrin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019741 ! pentacyclic triterpenoid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:1902381 ! 11-oxo-beta-amyrin metabolic process +created_by: ms +creation_date: 2013-09-03T12:55:38Z + +[Term] +id: GO:1902383 +name: 11-oxo-beta-amyrin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin." [GOC:TermGenie, pmid:22128119] +synonym: "11-oxo-beta-amyrin anabolism" EXACT [GOC:TermGenie] +synonym: "11-oxo-beta-amyrin biosynthesis" EXACT [GOC:TermGenie] +synonym: "11-oxo-beta-amyrin formation" EXACT [GOC:TermGenie] +synonym: "11-oxo-beta-amyrin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019745 ! pentacyclic triterpenoid biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1902381 ! 11-oxo-beta-amyrin metabolic process +created_by: ms +creation_date: 2013-09-03T12:55:46Z + +[Term] +id: GO:1902384 +name: glycyrrhetinate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glycyrrhetinate." [GOC:TermGenie, pmid:22128119] +synonym: "glycyrrhetinate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0019742 ! pentacyclic triterpenoid metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: ms +creation_date: 2013-09-03T12:55:55Z + +[Term] +id: GO:1902385 +name: glycyrrhetinate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate." [GOC:TermGenie, pmid:22128119] +synonym: "glycyrrhetinate breakdown" EXACT [GOC:TermGenie] +synonym: "glycyrrhetinate catabolism" EXACT [GOC:TermGenie] +synonym: "glycyrrhetinate degradation" EXACT [GOC:TermGenie] +is_a: GO:0019741 ! pentacyclic triterpenoid catabolic process +is_a: GO:0042182 ! ketone catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +is_a: GO:1902384 ! glycyrrhetinate metabolic process +created_by: ms +creation_date: 2013-09-03T12:56:10Z + +[Term] +id: GO:1902386 +name: glycyrrhetinate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glycyrrhetinate." [GOC:TermGenie, pmid:22128119] +synonym: "glycyrrhetinate anabolism" EXACT [GOC:TermGenie] +synonym: "glycyrrhetinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "glycyrrhetinate formation" EXACT [GOC:TermGenie] +synonym: "glycyrrhetinate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019745 ! pentacyclic triterpenoid biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1902384 ! glycyrrhetinate metabolic process +created_by: ms +creation_date: 2013-09-03T12:56:19Z + +[Term] +id: GO:1902387 +name: ceramide 1-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ceramide 1-phosphate." [GOC:TermGenie, PMID:23863933] +is_a: GO:0005543 ! phospholipid binding +is_a: GO:0097001 ! ceramide binding +created_by: uh +creation_date: 2013-09-05T05:51:08Z + +[Term] +id: GO:1902388 +name: ceramide 1-phosphate transfer activity +namespace: molecular_function +def: "Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GOC:TermGenie, PMID:23863933] +synonym: "ceramide 1-phosphate carrier activity" EXACT [] +synonym: "ceramide 1-phosphate transporter activity" BROAD [] +synonym: "intermembrane ceramide 1-phosphate transfer activity" NARROW [] +xref: Reactome:R-HSA-5339535 "GLTPD1 transports C1P from plasma membrane to Golgi membrane" +is_a: GO:0120014 ! phospholipid transfer activity +is_a: GO:0120017 ! ceramide transfer activity +relationship: part_of GO:1902389 ! ceramide 1-phosphate transport +created_by: uh +creation_date: 2013-09-05T05:57:55Z + +[Term] +id: GO:1902389 +name: ceramide 1-phosphate transport +namespace: biological_process +def: "The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie, PMID:23863933] +is_a: GO:0015914 ! phospholipid transport +is_a: GO:0035627 ! ceramide transport +created_by: uh +creation_date: 2013-09-05T06:02:35Z + +[Term] +id: GO:1902390 +name: regulation of N-terminal peptidyl-serine acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation." [GOC:TermGenie, PMID:23912279] +is_a: GO:1901983 ! regulation of protein acetylation +is_a: GO:1903317 ! regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017198 ! N-terminal peptidyl-serine acetylation +relationship: regulates GO:0017198 ! N-terminal peptidyl-serine acetylation +created_by: al +creation_date: 2013-09-11T14:46:45Z + +[Term] +id: GO:1902391 +name: positive regulation of N-terminal peptidyl-serine acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation." [GOC:TermGenie, PMID:23912279] +synonym: "activation of N-terminal peptidyl-serine acetylation" NARROW [GOC:TermGenie] +synonym: "up regulation of N-terminal peptidyl-serine acetylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of N-terminal peptidyl-serine acetylation" EXACT [GOC:TermGenie] +synonym: "upregulation of N-terminal peptidyl-serine acetylation" EXACT [GOC:TermGenie] +is_a: GO:1901985 ! positive regulation of protein acetylation +is_a: GO:1902390 ! regulation of N-terminal peptidyl-serine acetylation +is_a: GO:1903319 ! positive regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017198 ! N-terminal peptidyl-serine acetylation +relationship: positively_regulates GO:0017198 ! N-terminal peptidyl-serine acetylation +created_by: al +creation_date: 2013-09-11T14:46:54Z + +[Term] +id: GO:1902392 +name: regulation of exodeoxyribonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity." [GOC:jl, GOC:TermGenie] +is_a: GO:0032070 ! regulation of deoxyribonuclease activity +is_a: GO:1905777 ! regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004529 ! exodeoxyribonuclease activity +relationship: regulates GO:0004529 ! exodeoxyribonuclease activity +created_by: jl +creation_date: 2013-09-11T14:56:14Z + +[Term] +id: GO:1902393 +name: negative regulation of exodeoxyribonuclease activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity." [GOC:jl, GOC:TermGenie] +synonym: "down regulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +synonym: "downregulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +synonym: "inhibition of exodeoxyribonuclease activity" NARROW [GOC:TermGenie] +is_a: GO:0032076 ! negative regulation of deoxyribonuclease activity +is_a: GO:1902392 ! regulation of exodeoxyribonuclease activity +is_a: GO:1905778 ! negative regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004529 ! exodeoxyribonuclease activity +relationship: negatively_regulates GO:0004529 ! exodeoxyribonuclease activity +created_by: jl +creation_date: 2013-09-11T14:56:23Z + +[Term] +id: GO:1902394 +name: positive regulation of exodeoxyribonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity." [GOC:jl, GOC:TermGenie, PMID:1234] +synonym: "activation of exodeoxyribonuclease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +synonym: "upregulation of exodeoxyribonuclease activity" EXACT [GOC:TermGenie] +is_a: GO:0032077 ! positive regulation of deoxyribonuclease activity +is_a: GO:1902392 ! regulation of exodeoxyribonuclease activity +is_a: GO:1905779 ! positive regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004529 ! exodeoxyribonuclease activity +relationship: positively_regulates GO:0004529 ! exodeoxyribonuclease activity +created_by: jl +creation_date: 2013-09-11T14:56:38Z + +[Term] +id: GO:1902395 +name: regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity." [GOC:TermGenie, PMID:23612965] +synonym: "regulation of 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity" EXACT [GOC:TermGenie] +synonym: "regulation of 1-deoxyxylulose-5-phosphate synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DOXP synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DXP-synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008661 ! 1-deoxy-D-xylulose-5-phosphate synthase activity +relationship: regulates GO:0008661 ! 1-deoxy-D-xylulose-5-phosphate synthase activity +created_by: tb +creation_date: 2013-09-11T21:12:25Z + +[Term] +id: GO:1902396 +name: protein localization to bicellular tight junction +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction." [GOC:TermGenie, PMID:18332111] +synonym: "protein localisation in tight junction" EXACT [GOC:TermGenie] +synonym: "protein localisation to tight junction" EXACT [GOC:TermGenie] +synonym: "protein localization in tight junction" EXACT [GOC:TermGenie] +is_a: GO:0150105 ! protein localization to cell-cell junction +created_by: tb +creation_date: 2013-09-11T21:43:13Z + +[Term] +id: GO:1902397 +name: detection of stimulus involved in meiotic spindle checkpoint +namespace: biological_process +def: "Any detection of stimulus that is involved in meiotic spindle checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "perception of stimulus involved in meiotic spindle checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus detection involved in meiotic spindle checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in meiotic spindle checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0022414 ! reproductive process +is_a: GO:0051606 ! detection of stimulus +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044779 ! meiotic spindle checkpoint +relationship: part_of GO:0044779 ! meiotic spindle checkpoint +created_by: jl +creation_date: 2013-09-12T12:01:32Z + +[Term] +id: GO:1902398 +name: intracellular signal transduction involved in meiotic spindle checkpoint +namespace: biological_process +def: "Any intracellular signal transduction that is involved in meiotic spindle checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in meiotic spindle checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in meiotic spindle checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in meiotic spindle checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in meiotic spindle checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in meiotic spindle checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in meiotic spindle checkpoint" NARROW [GOC:TermGenie] +is_a: GO:0072411 ! signal transduction involved in meiotic cell cycle checkpoint +is_a: GO:0072416 ! signal transduction involved in spindle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0044779 ! meiotic spindle checkpoint +relationship: part_of GO:0044779 ! meiotic spindle checkpoint +created_by: jl +creation_date: 2013-09-12T12:01:41Z + +[Term] +id: GO:1902399 +name: detection of stimulus involved in G1 DNA damage checkpoint +namespace: biological_process +def: "Any detection of stimulus that is involved in G1 DNA damage checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "detection of stimulus involved in G1/S DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "perception of stimulus involved in G1 DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "perception of stimulus involved in G1/S DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus detection involved in G1 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus detection involved in G1/S DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in G1 DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus sensing involved in G1/S DNA damage checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0051606 ! detection of stimulus +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044783 ! G1 DNA damage checkpoint +relationship: part_of GO:0044783 ! G1 DNA damage checkpoint +created_by: jl +creation_date: 2013-09-12T12:01:49Z + +[Term] +id: GO:1902400 +name: intracellular signal transduction involved in G1 DNA damage checkpoint +namespace: biological_process +def: "Any intracellular signal transduction that is involved in G1 DNA damage checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "intracellular signal transduction involved in G1/S DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in G1 DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in G1/S DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in G1 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in G1/S DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in G1 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in G1/S DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in G1 DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in G1/S DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in G1 DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in G1/S DNA damage checkpoint" NARROW [GOC:TermGenie] +is_a: GO:0072422 ! signal transduction involved in DNA damage checkpoint +is_a: GO:1902807 ! negative regulation of cell cycle G1/S phase transition +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0044783 ! G1 DNA damage checkpoint +relationship: part_of GO:0044783 ! G1 DNA damage checkpoint +created_by: jl +creation_date: 2013-09-12T12:01:58Z + +[Term] +id: GO:1902401 +name: detection of stimulus involved in mitotic DNA damage checkpoint +namespace: biological_process +def: "Any detection of stimulus that is involved in mitotic DNA damage checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "perception of stimulus involved in mitotic DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus detection involved in mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in mitotic DNA damage checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072400 ! detection of stimulus involved in mitotic DNA integrity checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044773 ! mitotic DNA damage checkpoint +relationship: part_of GO:0044773 ! mitotic DNA damage checkpoint +created_by: jl +creation_date: 2013-09-12T12:07:12Z + +[Term] +id: GO:1902402 +name: signal transduction involved in mitotic DNA damage checkpoint +namespace: biological_process +def: "Any intracellular signal transduction that is involved in mitotic DNA damage checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in mitotic DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in mitotic DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in mitotic DNA damage checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in mitotic DNA damage checkpoint" NARROW [GOC:TermGenie] +is_a: GO:0072422 ! signal transduction involved in DNA damage checkpoint +is_a: GO:1902403 ! signal transduction involved in mitotic DNA integrity checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0044773 ! mitotic DNA damage checkpoint +relationship: part_of GO:0044773 ! mitotic DNA damage checkpoint +created_by: jl +creation_date: 2013-09-12T12:07:20Z + +[Term] +id: GO:1902403 +name: signal transduction involved in mitotic DNA integrity checkpoint +namespace: biological_process +def: "Any intracellular signal transduction that is involved in mitotic DNA integrity checkpoint." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction involved in topo II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction involved in topoisomerase II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in topo II checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in topoisomerase II checkpoint" NARROW [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in mitotic DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in topo II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in topoisomerase II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in mitotic DNA integrity checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in topo II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in topoisomerase II checkpoint" EXACT [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in mitotic DNA integrity checkpoint" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in topo II checkpoint" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in topoisomerase II checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in mitotic DNA integrity checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in topo II checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in topoisomerase II checkpoint" RELATED [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in mitotic DNA integrity checkpoint" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in topo II checkpoint" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in topoisomerase II checkpoint" NARROW [GOC:TermGenie] +is_a: GO:0072401 ! signal transduction involved in DNA integrity checkpoint +is_a: GO:0072413 ! signal transduction involved in mitotic cell cycle checkpoint +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0044774 ! mitotic DNA integrity checkpoint +relationship: part_of GO:0044774 ! mitotic DNA integrity checkpoint +created_by: jl +creation_date: 2013-09-12T12:07:28Z + +[Term] +id: GO:1902404 +name: mitotic actomyosin contractile ring contraction +namespace: biological_process +def: "Any actomyosin contractile ring contraction that is involved in mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0000916 ! actomyosin contractile ring contraction +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0000916 ! actomyosin contractile ring contraction +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-09-12T12:27:57Z + +[Term] +id: GO:1902405 +name: mitotic actomyosin contractile ring localization +namespace: biological_process +def: "Any actomyosin contractile ring localization that is involved in mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0032187 ! actomyosin contractile ring localization +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0032187 ! actomyosin contractile ring localization +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-09-12T12:28:05Z + +[Term] +id: GO:1902406 +name: mitotic actomyosin contractile ring maintenance +namespace: biological_process +def: "Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0031566 ! actomyosin contractile ring maintenance +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0031566 ! actomyosin contractile ring maintenance +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-09-12T12:28:14Z + +[Term] +id: GO:1902407 +name: assembly of actomyosin apparatus involved in mitotic cytokinesis +namespace: biological_process +def: "Any assembly of mitotic cytokinetic actomyosin apparatus." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0000912 ! assembly of actomyosin apparatus involved in cytokinesis +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0000912 ! assembly of actomyosin apparatus involved in cytokinesis +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-09-12T12:28:22Z + +[Term] +id: GO:1902408 +name: mitotic cytokinesis, site selection +namespace: biological_process +def: "Any cytokinesis, site selection that is involved in mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "site selection involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "site selection involved in cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0007105 ! cytokinesis, site selection +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0007105 ! cytokinesis, site selection +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2013-09-12T12:29:13Z + +[Term] +id: GO:1902410 +name: mitotic cytokinetic process +namespace: biological_process +def: "Any cytokinetic process that is involved in mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:TermGenie] +is_a: GO:0032506 ! cytokinetic process +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0032506 ! cytokinetic process +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000281 ! mitotic cytokinesis +created_by: jl +creation_date: 2013-09-12T12:29:36Z + +[Term] +id: GO:1902412 +name: regulation of mitotic cytokinesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cytokinesis." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0032465 ! regulation of cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000281 ! mitotic cytokinesis +relationship: regulates GO:0000281 ! mitotic cytokinesis +created_by: jl +creation_date: 2013-09-12T14:11:49Z + +[Term] +id: GO:1902413 +name: negative regulation of mitotic cytokinesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis." [GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "down regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cytokinesis after mitosis" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:1902412 ! regulation of mitotic cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000281 ! mitotic cytokinesis +relationship: negatively_regulates GO:0000281 ! mitotic cytokinesis +created_by: jl +creation_date: 2013-09-12T14:11:59Z + +[Term] +id: GO:1902414 +name: protein localization to cell junction +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111] +synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie] +synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie] +synonym: "protein localization in cell junction" EXACT [GOC:TermGenie] +is_a: GO:0008104 ! protein localization +created_by: tb +creation_date: 2013-09-13T16:55:57Z + +[Term] +id: GO:1902415 +name: regulation of mRNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA binding." [GOC:rb, GOC:TermGenie, PMID:22890846] +is_a: GO:1905214 ! regulation of RNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003729 ! mRNA binding +relationship: regulates GO:0003729 ! mRNA binding +created_by: rb +creation_date: 2013-09-13T18:57:15Z + +[Term] +id: GO:1902416 +name: positive regulation of mRNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA binding." [GOC:rb, GOC:TermGenie, PMID:22890846] +synonym: "activation of mRNA binding" NARROW [GOC:TermGenie] +synonym: "up regulation of mRNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA binding" EXACT [GOC:TermGenie] +is_a: GO:1902415 ! regulation of mRNA binding +is_a: GO:1905216 ! positive regulation of RNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003729 ! mRNA binding +relationship: positively_regulates GO:0003729 ! mRNA binding +created_by: rb +creation_date: 2013-09-13T18:57:24Z + +[Term] +id: GO:1902417 +name: (+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other." [GOC:TermGenie, PMID:24028845] +synonym: "ABA-GE transmembrane transporter activity" EXACT [] +synonym: "abscisic acid glucosyl ester transmembrane transporter activity" EXACT [] +is_a: GO:0042947 ! glucoside transmembrane transporter activity +relationship: part_of GO:1902418 ! (+)-abscisic acid D-glucopyranosyl ester transmembrane transport +created_by: tb +creation_date: 2013-09-16T22:37:11Z + +[Term] +id: GO:1902418 +name: (+)-abscisic acid D-glucopyranosyl ester transmembrane transport +namespace: biological_process +def: "The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane." [GOC:TermGenie, PMID:24028845] +synonym: "ABA-GE transmembrane transport" EXACT [] +synonym: "abscisic acid glucosyl ester transmembrane transport" EXACT [] +is_a: GO:0042946 ! glucoside transport +is_a: GO:0055085 ! transmembrane transport +created_by: tb +creation_date: 2013-09-16T22:37:20Z + +[Term] +id: GO:1902421 +name: hydrogen metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving H2 (dihydrogen)." [GOC:mengo_curators, GOC:TermGenie, PMID:20395274, PMID:20692761] +synonym: "dihydrogen metabolism" EXACT [GOC:TermGenie] +synonym: "H2 metabolism" EXACT [] +synonym: "molecular hydrogen metabolism" EXACT [] +is_a: GO:0008152 ! metabolic process +created_by: jl +creation_date: 2013-09-18T14:34:23Z + +[Term] +id: GO:1902422 +name: hydrogen biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of H2 (dihydrogen)." [GOC:mengo_curators, GOC:TermGenie, PMID:20395274, PMID:20692761] +synonym: "dihydrogen synthesis" EXACT [GOC:jl] +synonym: "H2 biosynthesis" EXACT [] +synonym: "hydrogen anabolism" EXACT [GOC:TermGenie] +synonym: "hydrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "hydrogen formation" EXACT [GOC:TermGenie] +synonym: "hydrogen generation" EXACT [GOC:jl] +synonym: "hydrogen production" EXACT [] +synonym: "hydrogen synthesis" EXACT [GOC:TermGenie] +synonym: "molecular hydrogen biosynthesis" EXACT [] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:1902421 ! hydrogen metabolic process +created_by: jl +creation_date: 2013-09-18T14:34:32Z + +[Term] +id: GO:1902423 +name: regulation of attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation." [GOC:TermGenie, GOC:vw, PMID:22065639] +synonym: "regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [] +synonym: "regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0051988 ! regulation of attachment of spindle microtubules to kinetochore +is_a: GO:0090235 ! regulation of metaphase plate congression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +relationship: regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +created_by: vw +creation_date: 2013-09-19T10:33:38Z + +[Term] +id: GO:1902424 +name: negative regulation of attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation." [GOC:TermGenie, GOC:vw, PMID:22065639] +synonym: "down regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "down regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "down regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "down regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "down-regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "down-regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "downregulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "downregulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "downregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "downregulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "inhibition of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "inhibition of attachment of spindle microtubules to kinetochore involved in mitosis" NARROW [GOC:TermGenie] +synonym: "inhibition of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" NARROW [GOC:TermGenie] +synonym: "inhibition of attachment of spindle microtubules to mitotic chromosome" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "negative regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [] +synonym: "negative regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitotic attachment of spindle microtubules to kinetochore" EXACT [] +synonym: "negative regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:0051986 ! negative regulation of attachment of spindle microtubules to kinetochore +is_a: GO:1902423 ! regulation of attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +relationship: negatively_regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +created_by: vw +creation_date: 2013-09-19T10:33:46Z + +[Term] +id: GO:1902425 +name: positive regulation of attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation." [GOC:TermGenie, PMID:22065639] +synonym: "activation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "activation of attachment of spindle microtubules to kinetochore involved in mitosis" NARROW [GOC:TermGenie] +synonym: "activation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" NARROW [GOC:TermGenie] +synonym: "activation of attachment of spindle microtubules to mitotic chromosome" NARROW [GOC:TermGenie] +synonym: "activation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [] +synonym: "positive regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore during mitosis" RELATED [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore involved in mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to mitotic chromosome" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic bipolar attachment" RELATED [GOC:TermGenie] +is_a: GO:0051987 ! positive regulation of attachment of spindle microtubules to kinetochore +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +is_a: GO:1902423 ! regulation of attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +relationship: positively_regulates GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +created_by: vw +creation_date: 2013-09-19T10:33:55Z + +[Term] +id: GO:1902426 +name: deactivation of mitotic spindle assembly checkpoint +namespace: biological_process +def: "A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint." [GOC:dph, GOC:TermGenie, GOC:vw, PMID:19075002, PMID:19592249] +comment: A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known. +synonym: "down regulation of Mad2-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "down regulation of mitotic cell cycle spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "down regulation of mitotic spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "down-regulation of Mad2-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "down-regulation of mitotic cell cycle spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "down-regulation of mitotic spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "downregulation of Mad2-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "downregulation of mitotic cell cycle spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "downregulation of mitotic spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "inhibition of Mad2-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "inhibition of mitotic cell cycle spindle assembly checkpoint" RELATED [GOC:TermGenie] +synonym: "inhibition of mitotic spindle assembly checkpoint" RELATED [GOC:TermGenie] +synonym: "mitotic spindle assembly checkpoint silencing" EXACT [] +synonym: "mitotic spindle assembly deactivation" EXACT [] +synonym: "negative regulation of Mad2-dependent checkpoint" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitotic cell cycle spindle assembly checkpoint" BROAD [GOC:TermGenie] +synonym: "negative regulation of mitotic spindle assembly checkpoint" BROAD [] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045842 ! positive regulation of mitotic metaphase/anaphase transition +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:0090233 ! negative regulation of spindle checkpoint +is_a: GO:0090266 ! regulation of mitotic cell cycle spindle assembly checkpoint +relationship: negatively_regulates GO:0007094 ! mitotic spindle assembly checkpoint +created_by: dph +creation_date: 2013-09-20T18:42:07Z + +[Term] +id: GO:1902427 +name: regulation of water channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of water channel activity." [GOC:nhn, GOC:TermGenie, PMID:22095752] +synonym: "regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "regulation of aquaporin permeability" NARROW [PMID:22095752] +is_a: GO:0022898 ! regulation of transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015250 ! water channel activity +relationship: regulates GO:0015250 ! water channel activity +created_by: bf +creation_date: 2013-09-23T12:56:31Z + +[Term] +id: GO:1902428 +name: negative regulation of water channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity." [GOC:TermGenie] +synonym: "down regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "down regulation of water channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "down-regulation of water channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "downregulation of water channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of aquaporin" NARROW [GOC:TermGenie] +synonym: "inhibition of water channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of aquaporin" NARROW [GOC:TermGenie] +is_a: GO:0032410 ! negative regulation of transporter activity +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:1902427 ! regulation of water channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015250 ! water channel activity +relationship: negatively_regulates GO:0015250 ! water channel activity +created_by: bf +creation_date: 2013-09-23T12:56:40Z + +[Term] +id: GO:1902429 +name: positive regulation of water channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of water channel activity." [GOC:nhn, GOC:TermGenie, PMID:22095752] +synonym: "activation of aquaporin" NARROW [GOC:TermGenie] +synonym: "activation of water channel activity" NARROW [GOC:TermGenie] +synonym: "aquaporin activation" NARROW [PMID:22095752] +synonym: "positive regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "up regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "up regulation of water channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "up-regulation of water channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aquaporin" NARROW [GOC:TermGenie] +synonym: "upregulation of water channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032411 ! positive regulation of transporter activity +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:1902427 ! regulation of water channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015250 ! water channel activity +relationship: positively_regulates GO:0015250 ! water channel activity +created_by: bf +creation_date: 2013-09-23T12:56:49Z + +[Term] +id: GO:1902430 +name: negative regulation of amyloid-beta formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation." [GOC:hjd, GOC:TermGenie, PMID:22992957] +synonym: "down regulation of beta-amyloid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-amyloid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-amyloid formation" EXACT [GOC:TermGenie] +synonym: "inhibition of beta-amyloid formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-amyloid formation" EXACT [] +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:1902003 ! regulation of amyloid-beta formation +is_a: GO:1902992 ! negative regulation of amyloid precursor protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034205 ! amyloid-beta formation +relationship: negatively_regulates GO:0034205 ! amyloid-beta formation +created_by: hjd +creation_date: 2013-09-25T17:41:01Z + +[Term] +id: GO:1902432 +name: protein localization to division septum +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a division septum." [GOC:TermGenie, PMID:9367977] +synonym: "protein localisation in division septum" EXACT [GOC:TermGenie] +synonym: "protein localisation to division septum" EXACT [GOC:TermGenie] +synonym: "protein localization in division septum" EXACT [GOC:TermGenie] +is_a: GO:0072741 ! protein localization to cell division site +created_by: mah +creation_date: 2013-09-30T14:29:51Z + +[Term] +id: GO:1902433 +name: positive regulation of water channel activity involved in maintenance of lens transparency +namespace: biological_process +def: "Any positive regulation of water channel activity that is involved in maintenance of lens transparency." [GOC:nhn, GOC:TermGenie, PMID:22095752] +synonym: "activation of aquaporin involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "activation of aquaporin involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "activation of aquaporin involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "activation of water channel activity involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "activation of water channel activity involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "activation of water channel activity involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "aquaporin activation involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "aquaporin activation involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "aquaporin activation involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "positive regulation of aquaporin involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "positive regulation of aquaporin involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "positive regulation of aquaporin involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "positive regulation of water channel activity involved in maintenance of ocular lens transparency" EXACT [GOC:TermGenie] +synonym: "positive regulation of water channel activity involved in preservation of lens transparency" EXACT [GOC:TermGenie] +synonym: "up regulation of aquaporin involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "up regulation of aquaporin involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "up regulation of aquaporin involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "up regulation of water channel activity involved in maintenance of lens transparency" EXACT [GOC:TermGenie] +synonym: "up regulation of water channel activity involved in maintenance of ocular lens transparency" EXACT [GOC:TermGenie] +synonym: "up regulation of water channel activity involved in preservation of lens transparency" EXACT [GOC:TermGenie] +synonym: "up-regulation of aquaporin involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "up-regulation of aquaporin involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "up-regulation of aquaporin involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "up-regulation of water channel activity involved in maintenance of lens transparency" EXACT [GOC:TermGenie] +synonym: "up-regulation of water channel activity involved in maintenance of ocular lens transparency" EXACT [GOC:TermGenie] +synonym: "up-regulation of water channel activity involved in preservation of lens transparency" EXACT [GOC:TermGenie] +synonym: "upregulation of aquaporin involved in maintenance of lens transparency" NARROW [GOC:TermGenie] +synonym: "upregulation of aquaporin involved in maintenance of ocular lens transparency" NARROW [GOC:TermGenie] +synonym: "upregulation of aquaporin involved in preservation of lens transparency" NARROW [GOC:TermGenie] +synonym: "upregulation of water channel activity involved in maintenance of lens transparency" EXACT [GOC:TermGenie] +synonym: "upregulation of water channel activity involved in maintenance of ocular lens transparency" EXACT [GOC:TermGenie] +synonym: "upregulation of water channel activity involved in preservation of lens transparency" EXACT [GOC:TermGenie] +is_a: GO:1902429 ! positive regulation of water channel activity +intersection_of: GO:1902429 ! positive regulation of water channel activity +intersection_of: part_of GO:0036438 ! maintenance of lens transparency +relationship: part_of GO:0036438 ! maintenance of lens transparency +created_by: bf +creation_date: 2013-10-02T12:58:00Z + +[Term] +id: GO:1902434 +name: sulfate import across plasma membrane +namespace: biological_process +def: "The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol." [GOC:TermGenie, PMID:14723223] +synonym: "sulfate import into cell" EXACT [] +synonym: "sulphate import into cell" EXACT [] +is_a: GO:0098658 ! inorganic anion import across plasma membrane +is_a: GO:1902358 ! sulfate transmembrane transport +created_by: mah +creation_date: 2013-10-07T14:12:38Z + +[Term] +id: GO:1902435 +name: regulation of male mating behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of male mating behavior." [GOC:TermGenie, PMID:24089208] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0050795 ! regulation of behavior +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060179 ! male mating behavior +relationship: regulates GO:0060179 ! male mating behavior +created_by: mm2 +creation_date: 2013-10-09T15:49:56Z + +[Term] +id: GO:1902436 +name: negative regulation of male mating behavior +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior." [GOC:TermGenie, PMID:24089208] +synonym: "down regulation of male mating behavior" EXACT [GOC:TermGenie] +synonym: "down-regulation of male mating behavior" EXACT [GOC:TermGenie] +synonym: "downregulation of male mating behavior" EXACT [GOC:TermGenie] +synonym: "inhibition of male mating behavior" NARROW [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902435 ! regulation of male mating behavior +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060179 ! male mating behavior +relationship: negatively_regulates GO:0060179 ! male mating behavior +created_by: mm2 +creation_date: 2013-10-09T15:50:05Z + +[Term] +id: GO:1902437 +name: positive regulation of male mating behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of male mating behavior." [GOC:TermGenie, PMID:24089208] +synonym: "activation of male mating behavior" NARROW [GOC:TermGenie] +synonym: "up regulation of male mating behavior" EXACT [GOC:TermGenie] +synonym: "up-regulation of male mating behavior" EXACT [GOC:TermGenie] +synonym: "upregulation of male mating behavior" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902435 ! regulation of male mating behavior +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060179 ! male mating behavior +relationship: positively_regulates GO:0060179 ! male mating behavior +created_by: mm2 +creation_date: 2013-10-09T15:50:14Z + +[Term] +id: GO:1902438 +name: response to vanadate(3-) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus." [GOC:di, GOC:TermGenie, PMID:7489911] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: di +creation_date: 2013-10-10T10:50:21Z + +[Term] +id: GO:1902439 +name: cellular response to vanadate(3-) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus." [GOC:di, GOC:TermGenie, PMID:7489911] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1902438 ! response to vanadate(3-) +created_by: di +creation_date: 2013-10-10T10:50:30Z + +[Term] +id: GO:1902440 +name: protein localization to mitotic spindle pole body +namespace: biological_process +alt_id: GO:1990975 +def: "A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body." [GOC:TermGenie, PMID:22438582] +synonym: "establishment of protein localization to mitotic spindle pole body" NARROW [] +synonym: "protein localisation in mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "protein localization in mitotic spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:0071988 ! protein localization to spindle pole body +created_by: mah +creation_date: 2013-10-10T14:44:55Z + +[Term] +id: GO:1902441 +name: protein localization to meiotic spindle pole body +namespace: biological_process +alt_id: GO:1990945 +alt_id: GO:1990954 +def: "A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body." [PMID:20833892] +synonym: "establishment of protein localization to meiotic spindle pole body" NARROW [] +synonym: "protein localisation in meiotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "protein localisation to meiotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "protein localization in meiotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "protein location to meiotic spindle pole body" EXACT [] +is_a: GO:0071988 ! protein localization to spindle pole body +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:1990395 ! meiotic spindle pole body organization +created_by: mah +creation_date: 2013-10-10T14:45:04Z + +[Term] +id: GO:1902442 +name: regulation of ripoptosome assembly involved in necroptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:21052097] +synonym: "regulation of ripoptosome assembly involved in necroptosis" NARROW [] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:0060544 ! regulation of necroptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901026 ! ripoptosome assembly involved in necroptotic process +relationship: regulates GO:1901026 ! ripoptosome assembly involved in necroptotic process +created_by: dph +creation_date: 2013-10-10T17:51:33Z + +[Term] +id: GO:1902443 +name: negative regulation of ripoptosome assembly involved in necroptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:21052097] +synonym: "down regulation of ripoptosome assembly involved in necroptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ripoptosome assembly involved in necroptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of ripoptosome assembly involved in necroptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of ripoptosome assembly involved in necroptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of ripoptosome assembly involved in necroptosis" NARROW [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0060546 ! negative regulation of necroptotic process +is_a: GO:1902442 ! regulation of ripoptosome assembly involved in necroptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901026 ! ripoptosome assembly involved in necroptotic process +relationship: negatively_regulates GO:1901026 ! ripoptosome assembly involved in necroptotic process +created_by: dph +creation_date: 2013-10-10T17:51:41Z + +[Term] +id: GO:1902444 +name: riboflavin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with riboflavin." [GOC:TermGenie, PMID:12083520] +is_a: GO:0008144 ! drug binding +is_a: GO:0019842 ! vitamin binding +is_a: GO:0043168 ! anion binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: al +creation_date: 2013-10-11T08:44:52Z + +[Term] +id: GO:1902445 +name: regulation of mitochondrial membrane permeability involved in programmed necrotic cell death +namespace: biological_process +def: "Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:22493254] +synonym: "regulation of transport across mitochondrial membrane involved in programmed necrotic cell death" EXACT [GOC:TermGenie] +is_a: GO:0046902 ! regulation of mitochondrial membrane permeability +intersection_of: GO:0046902 ! regulation of mitochondrial membrane permeability +intersection_of: part_of GO:0097300 ! programmed necrotic cell death +relationship: part_of GO:0097300 ! programmed necrotic cell death +created_by: dph +creation_date: 2013-10-11T13:11:20Z + +[Term] +id: GO:1902446 +name: regulation of shade avoidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shade avoidance." [GOC:TermGenie, PMID:23763263] +is_a: GO:2000030 ! regulation of response to red or far red light +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009641 ! shade avoidance +relationship: regulates GO:0009641 ! shade avoidance +created_by: dhl +creation_date: 2013-10-15T21:04:36Z + +[Term] +id: GO:1902447 +name: negative regulation of shade avoidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance." [GOC:TermGenie, PMID:23763263] +synonym: "down regulation of shade avoidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of shade avoidance" EXACT [GOC:TermGenie] +synonym: "downregulation of shade avoidance" EXACT [GOC:TermGenie] +synonym: "inhibition of shade avoidance" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1902446 ! regulation of shade avoidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009641 ! shade avoidance +relationship: negatively_regulates GO:0009641 ! shade avoidance +created_by: dhl +creation_date: 2013-10-15T21:04:51Z + +[Term] +id: GO:1902448 +name: positive regulation of shade avoidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of shade avoidance." [GOC:TermGenie, PMID:23763263] +synonym: "activation of shade avoidance" NARROW [GOC:TermGenie] +synonym: "up regulation of shade avoidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of shade avoidance" EXACT [GOC:TermGenie] +synonym: "upregulation of shade avoidance" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1902446 ! regulation of shade avoidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009641 ! shade avoidance +relationship: positively_regulates GO:0009641 ! shade avoidance +created_by: dhl +creation_date: 2013-10-15T21:05:00Z + +[Term] +id: GO:1902455 +name: negative regulation of stem cell population maintenance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] +synonym: "down regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie] +synonym: "inhibition of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "inhibition of stem cell maintenance" NARROW [GOC:TermGenie] +synonym: "negative regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000036 ! regulation of stem cell population maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019827 ! stem cell population maintenance +relationship: negatively_regulates GO:0019827 ! stem cell population maintenance +created_by: cjm +creation_date: 2013-10-16T22:19:17Z + +[Term] +id: GO:1902456 +name: regulation of stomatal opening +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stomatal opening." [GOC:TermGenie, PMID:23766366] +is_a: GO:0010119 ! regulation of stomatal movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990069 ! stomatal opening +relationship: regulates GO:1990069 ! stomatal opening +created_by: tb +creation_date: 2013-10-16T22:25:06Z + +[Term] +id: GO:1902457 +name: negative regulation of stomatal opening +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening." [GOC:TermGenie, PMID:23766366] +synonym: "down regulation of stomatal opening" EXACT [GOC:TermGenie] +synonym: "down-regulation of stomatal opening" EXACT [GOC:TermGenie] +synonym: "downregulation of stomatal opening" EXACT [GOC:TermGenie] +synonym: "inhibition of stomatal opening" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1902456 ! regulation of stomatal opening +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990069 ! stomatal opening +relationship: negatively_regulates GO:1990069 ! stomatal opening +created_by: tb +creation_date: 2013-10-16T22:25:22Z + +[Term] +id: GO:1902458 +name: positive regulation of stomatal opening +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stomatal opening." [GOC:TermGenie, PMID:23766366] +synonym: "activation of stomatal opening" NARROW [GOC:TermGenie] +synonym: "up regulation of stomatal opening" EXACT [GOC:TermGenie] +synonym: "up-regulation of stomatal opening" EXACT [GOC:TermGenie] +synonym: "upregulation of stomatal opening" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1902456 ! regulation of stomatal opening +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990069 ! stomatal opening +relationship: positively_regulates GO:1990069 ! stomatal opening +created_by: tb +creation_date: 2013-10-16T22:25:33Z + +[Term] +id: GO:1902459 +name: positive regulation of stem cell population maintenance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] +synonym: "activation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "activation of stem cell maintenance" NARROW [GOC:TermGenie] +synonym: "positive regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "up regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000036 ! regulation of stem cell population maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019827 ! stem cell population maintenance +relationship: positively_regulates GO:0019827 ! stem cell population maintenance +created_by: cjm +creation_date: 2013-10-16T22:27:47Z + +[Term] +id: GO:1902460 +name: regulation of mesenchymal stem cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation." [GOC:pm, GOC:TermGenie, PMID:18672106] +synonym: "regulation of MSC proliferation" EXACT [GOC:TermGenie] +is_a: GO:0072091 ! regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097168 ! mesenchymal stem cell proliferation +relationship: regulates GO:0097168 ! mesenchymal stem cell proliferation +created_by: pm +creation_date: 2013-10-22T10:01:00Z + +[Term] +id: GO:1902461 +name: negative regulation of mesenchymal stem cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation." [GOC:pm, GOC:TermGenie, PMID:18672106] +synonym: "down regulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of mesenchymal stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of MSC proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of MSC proliferation" EXACT [GOC:TermGenie] +is_a: GO:1902460 ! regulation of mesenchymal stem cell proliferation +is_a: GO:2000647 ! negative regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097168 ! mesenchymal stem cell proliferation +relationship: negatively_regulates GO:0097168 ! mesenchymal stem cell proliferation +created_by: pm +creation_date: 2013-10-22T10:01:08Z + +[Term] +id: GO:1902462 +name: positive regulation of mesenchymal stem cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation." [GOC:pm, GOC:TermGenie, PMID:18672106] +synonym: "activation of mesenchymal stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of MSC proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of MSC proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of mesenchymal stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of MSC proliferation" EXACT [GOC:TermGenie] +is_a: GO:1902460 ! regulation of mesenchymal stem cell proliferation +is_a: GO:2000648 ! positive regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097168 ! mesenchymal stem cell proliferation +relationship: positively_regulates GO:0097168 ! mesenchymal stem cell proliferation +created_by: pm +creation_date: 2013-10-22T10:01:17Z + +[Term] +id: GO:1902463 +name: protein localization to cell leading edge +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326] +synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie] +is_a: GO:0034613 ! cellular protein localization +created_by: jl +creation_date: 2013-10-22T12:36:07Z + +[Term] +id: GO:1902464 +name: regulation of histone H3-K27 trimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation." [GOC:TermGenie, PMID:19270745] +is_a: GO:0061085 ! regulation of histone H3-K27 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098532 ! histone H3-K27 trimethylation +relationship: regulates GO:0098532 ! histone H3-K27 trimethylation +created_by: krc +creation_date: 2013-10-22T14:58:55Z + +[Term] +id: GO:1902465 +name: negative regulation of histone H3-K27 trimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation." [GOC:TermGenie, PMID:19270745] +synonym: "down regulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3-K27 trimethylation" NARROW [GOC:TermGenie] +is_a: GO:0061086 ! negative regulation of histone H3-K27 methylation +is_a: GO:1902464 ! regulation of histone H3-K27 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098532 ! histone H3-K27 trimethylation +relationship: negatively_regulates GO:0098532 ! histone H3-K27 trimethylation +created_by: krc +creation_date: 2013-10-22T14:59:04Z + +[Term] +id: GO:1902466 +name: positive regulation of histone H3-K27 trimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation." [GOC:TermGenie, PMID:19270745] +synonym: "activation of histone H3-K27 trimethylation" NARROW [GOC:TermGenie] +synonym: "up regulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K27 trimethylation" EXACT [GOC:TermGenie] +is_a: GO:0061087 ! positive regulation of histone H3-K27 methylation +is_a: GO:1902464 ! regulation of histone H3-K27 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098532 ! histone H3-K27 trimethylation +relationship: positively_regulates GO:0098532 ! histone H3-K27 trimethylation +created_by: krc +creation_date: 2013-10-22T14:59:19Z + +[Term] +id: GO:1902471 +name: regulation of mitotic actomyosin contractile ring localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization." [GOC:TermGenie, PMID:19959363, PMID:21246752, PMID:22786806] +is_a: GO:1901648 ! regulation of actomyosin contractile ring localization +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902405 ! mitotic actomyosin contractile ring localization +relationship: regulates GO:1902405 ! mitotic actomyosin contractile ring localization +created_by: mah +creation_date: 2013-10-24T14:20:03Z + +[Term] +id: GO:1902472 +name: regulation of mitotic cytokinesis, site selection +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection." [GOC:TermGenie, PMID:19959363, PMID:21246752, PMID:22786806] +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +is_a: GO:2000073 ! regulation of cytokinesis, site selection +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902408 ! mitotic cytokinesis, site selection +relationship: regulates GO:1902408 ! mitotic cytokinesis, site selection +created_by: mah +creation_date: 2013-10-24T14:20:12Z + +[Term] +id: GO:1902473 +name: regulation of protein localization to synapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] +synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie] +is_a: GO:0032880 ! regulation of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035418 ! protein localization to synapse +relationship: regulates GO:0035418 ! protein localization to synapse +created_by: kmv +creation_date: 2013-10-25T15:09:09Z + +[Term] +id: GO:1902474 +name: positive regulation of protein localization to synapse +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] +synonym: "activation of protein localisation to synapse" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to synapse" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1902473 ! regulation of protein localization to synapse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035418 ! protein localization to synapse +relationship: positively_regulates GO:0035418 ! protein localization to synapse +created_by: kmv +creation_date: 2013-10-25T15:09:18Z + +[Term] +id: GO:1902475 +name: L-alpha-amino acid transmembrane transport +namespace: biological_process +def: "The directed movement of L-alpha-amino acid across a membrane." [GOC:kmv, GOC:TermGenie, PMID:14668347] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015807 ! L-amino acid transport +created_by: kmv +creation_date: 2013-10-25T15:17:39Z + +[Term] +id: GO:1902476 +name: chloride transmembrane transport +namespace: biological_process +def: "The process in which chloride is transported across a membrane." [GOC:TermGenie, GOC:vw] +is_a: GO:0006821 ! chloride transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: bf +creation_date: 2013-10-28T09:44:29Z + +[Term] +id: GO:1902477 +name: regulation of defense response to bacterium, incompatible interaction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to bacterium, incompatible interaction." [GOC:TermGenie, PMID:24134885] +synonym: "regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:1900424 ! regulation of defense response to bacterium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009816 ! defense response to bacterium, incompatible interaction +relationship: regulates GO:0009816 ! defense response to bacterium, incompatible interaction +created_by: tb +creation_date: 2013-10-30T20:13:13Z + +[Term] +id: GO:1902478 +name: negative regulation of defense response to bacterium, incompatible interaction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium, incompatible interaction." [GOC:TermGenie, PMID:24134885] +synonym: "down regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down regulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "down regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "down regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "down regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "down-regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "down-regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "downregulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "downregulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "downregulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "downregulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "downregulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "downregulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "downregulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "downregulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "inhibition of defence response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "inhibition of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "inhibition of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "inhibition of defense response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "inhibition of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] +synonym: "inhibition of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] +synonym: "inhibition of response to pathogenic bacteria (incompatible interaction)" NARROW [GOC:TermGenie] +synonym: "inhibition of response to pathogenic bacterium (incompatible interaction)" NARROW [GOC:TermGenie] +synonym: "negative regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "negative regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "negative regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "negative regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "negative regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:1900425 ! negative regulation of defense response to bacterium +is_a: GO:1902477 ! regulation of defense response to bacterium, incompatible interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009816 ! defense response to bacterium, incompatible interaction +relationship: negatively_regulates GO:0009816 ! defense response to bacterium, incompatible interaction +created_by: tb +creation_date: 2013-10-30T20:13:22Z + +[Term] +id: GO:1902479 +name: positive regulation of defense response to bacterium, incompatible interaction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium, incompatible interaction." [GOC:TermGenie, PMID:24134885] +synonym: "activation of defence response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "activation of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "activation of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "activation of defense response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] +synonym: "activation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] +synonym: "activation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] +synonym: "activation of response to pathogenic bacteria (incompatible interaction)" NARROW [GOC:TermGenie] +synonym: "activation of response to pathogenic bacterium (incompatible interaction)" NARROW [GOC:TermGenie] +synonym: "positive regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "positive regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "positive regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "positive regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "positive regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "up regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up regulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "up regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "up regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "up regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "up-regulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "up-regulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "upregulation of defence response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "upregulation of defence response to pathogenic bacteria, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "upregulation of defence response to pathogenic bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "upregulation of defense response to bacterium, incompatible interaction" EXACT [GOC:TermGenie] +synonym: "upregulation of resistance response to pathogenic bacteria" EXACT [GOC:TermGenie] +synonym: "upregulation of resistance response to pathogenic bacterium" EXACT [GOC:TermGenie] +synonym: "upregulation of response to pathogenic bacteria (incompatible interaction)" EXACT [GOC:TermGenie] +synonym: "upregulation of response to pathogenic bacterium (incompatible interaction)" EXACT [GOC:TermGenie] +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:1900426 ! positive regulation of defense response to bacterium +is_a: GO:1902477 ! regulation of defense response to bacterium, incompatible interaction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009816 ! defense response to bacterium, incompatible interaction +relationship: positively_regulates GO:0009816 ! defense response to bacterium, incompatible interaction +created_by: tb +creation_date: 2013-10-30T20:13:31Z + +[Term] +id: GO:1902480 +name: protein localization to mitotic spindle +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a mitotic spindle." [GOC:TermGenie, PMID:23885124] +synonym: "protein localisation in mitotic spindle" EXACT [GOC:TermGenie] +synonym: "protein localisation to mitotic spindle" EXACT [GOC:TermGenie] +synonym: "protein localization in mitotic spindle" EXACT [GOC:TermGenie] +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +created_by: mah +creation_date: 2013-11-04T13:16:47Z + +[Term] +id: GO:1902481 +name: gamma-tubulin complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex." [GOC:TermGenie, PMID:23885124] +synonym: "gamma-tubulin complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2013-11-04T13:21:12Z + +[Term] +id: GO:1902482 +name: regulatory T cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a regulatory T cell." [GOC:nhn, GOC:TermGenie, PMID:20471291] +synonym: "regulatory T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulatory T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulatory T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulatory T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulatory T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulatory T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulatory T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070231 ! T cell apoptotic process +created_by: nhn +creation_date: 2013-11-04T17:18:09Z + +[Term] +id: GO:1902483 +name: cytotoxic T cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a cytotoxic T cell." [GOC:nhn, GOC:TermGenie, PMID:19604492] +synonym: "cytotoxic T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "cytotoxic T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "cytotoxic T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "cytotoxic T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "cytotoxic T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "cytotoxic T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "cytotoxic T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070231 ! T cell apoptotic process +created_by: nhn +creation_date: 2013-11-04T17:23:48Z + +[Term] +id: GO:1902484 +name: Sertoli cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895] +synonym: "Sertoli cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: pr +creation_date: 2013-11-06T11:27:34Z + +[Term] +id: GO:1902485 +name: L-cysteine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with L-cysteine." [GOC:bhm, GOC:TermGenie, PMID:12941942] +is_a: GO:0016597 ! amino acid binding +is_a: GO:0043169 ! cation binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bhm +creation_date: 2013-11-12T09:06:28Z + +[Term] +id: GO:1902486 +name: protein localization to growing cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a growing cell tip." [GOC:TermGenie, PMID:23041194] +synonym: "protein localisation in growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization in growing cell tip" EXACT [GOC:TermGenie] +is_a: GO:1990151 ! protein localization to cell tip +created_by: mah +creation_date: 2013-11-12T16:38:13Z + +[Term] +id: GO:1902487 +name: protein localization to non-growing cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip." [GOC:TermGenie, PMID:21652630, PMID:23041194] +synonym: "protein localisation in non-growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to non-growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization in non-growing cell tip" EXACT [GOC:TermGenie] +is_a: GO:1990151 ! protein localization to cell tip +created_by: mah +creation_date: 2013-11-12T16:38:22Z + +[Term] +id: GO:1902488 +name: cholangiocyte apoptotic process +namespace: biological_process +def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800] +synonym: "cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: cls +creation_date: 2013-11-12T15:30:08Z + +[Term] +id: GO:1902489 +name: hepatoblast apoptotic process +namespace: biological_process +def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967] +synonym: "hepatoblast apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +created_by: cls +creation_date: 2013-11-12T17:02:52Z + +[Term] +id: GO:1902490 +name: regulation of sperm capacitation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] +synonym: "regulation of sperm activation" RELATED [GOC:TermGenie] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:1903429 ! regulation of cell maturation +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048240 ! sperm capacitation +relationship: regulates GO:0048240 ! sperm capacitation +created_by: hjd +creation_date: 2013-11-12T21:17:03Z + +[Term] +id: GO:1902491 +name: negative regulation of sperm capacitation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] +synonym: "down regulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie] +synonym: "downregulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie] +synonym: "inhibition of sperm activation" RELATED [GOC:TermGenie] +synonym: "inhibition of sperm capacitation" NARROW [GOC:TermGenie] +synonym: "negative regulation of sperm activation" RELATED [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902490 ! regulation of sperm capacitation +is_a: GO:1903430 ! negative regulation of cell maturation +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048240 ! sperm capacitation +relationship: negatively_regulates GO:0048240 ! sperm capacitation +created_by: hjd +creation_date: 2013-11-12T21:17:12Z + +[Term] +id: GO:1902492 +name: positive regulation of sperm capacitation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] +synonym: "activation of sperm activation" RELATED [GOC:TermGenie] +synonym: "activation of sperm capacitation" NARROW [GOC:TermGenie] +synonym: "positive regulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "up regulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie] +synonym: "upregulation of sperm activation" RELATED [GOC:TermGenie] +synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902490 ! regulation of sperm capacitation +is_a: GO:1903431 ! positive regulation of cell maturation +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048240 ! sperm capacitation +relationship: positively_regulates GO:0048240 ! sperm capacitation +created_by: hjd +creation_date: 2013-11-12T21:17:21Z + +[Term] +id: GO:1902493 +name: acetyltransferase complex +namespace: cellular_component +def: "A protein complex which is capable of acetyltransferase activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] +is_a: GO:1990234 ! transferase complex +created_by: bhm +creation_date: 2013-11-13T16:16:45Z + +[Term] +id: GO:1902494 +name: catalytic complex +namespace: cellular_component +def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] +subset: goslim_metagenomics +synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2013-11-13T16:18:47Z + +[Term] +id: GO:1902495 +name: transmembrane transporter complex +namespace: cellular_component +def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1990351 ! transporter complex +relationship: part_of GO:0016021 ! integral component of membrane +created_by: bhm +creation_date: 2013-11-13T16:23:04Z + +[Term] +id: GO:1902496 +name: obsolete protein binding involved in negative regulation of telomere maintenance via telomerase +namespace: molecular_function +def: "OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase." [GOC:dph, GOC:TermGenie, GOC:vw, PMID:24013504] +comment: The reason for obsoletion is that this should be captured as a GO-CAM model. +synonym: "protein binding involved in down regulation of telomere maintenance via telomerase activity" EXACT [GOC:TermGenie] +synonym: "protein binding involved in down-regulation of telomere maintenance via telomerase activity" EXACT [GOC:TermGenie] +synonym: "protein binding involved in downregulation of telomere maintenance via telomerase activity" EXACT [GOC:TermGenie] +synonym: "protein binding involved in inhibition of telomere maintenance via telomerase" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: dph +creation_date: 2013-11-13T16:22:49Z + +[Term] +id: GO:1902497 +name: iron-sulfur cluster transport +namespace: biological_process +def: "The directed movement of an iron-sulfur cluster into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:TermGenie, PMID:19810706] +is_a: GO:0051181 ! cofactor transport +is_a: GO:1901678 ! iron coordination entity transport +created_by: dph +creation_date: 2013-11-13T16:33:00Z + +[Term] +id: GO:1902498 +name: regulation of protein autoubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein autoubiquitination." [GOC:rb, GOC:TermGenie, PMID:24069405] +synonym: "regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +is_a: GO:0031396 ! regulation of protein ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051865 ! protein autoubiquitination +relationship: regulates GO:0051865 ! protein autoubiquitination +created_by: rb +creation_date: 2013-11-13T21:03:28Z + +[Term] +id: GO:1902499 +name: positive regulation of protein autoubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein autoubiquitination." [GOC:rb, GOC:TermGenie, PMID:24069405] +synonym: "activation of protein auto-ubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein auto-ubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of protein autoubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein autoubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of protein self-ubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein self-ubiquitinylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +is_a: GO:0031398 ! positive regulation of protein ubiquitination +is_a: GO:1902498 ! regulation of protein autoubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051865 ! protein autoubiquitination +relationship: positively_regulates GO:0051865 ! protein autoubiquitination +created_by: rb +creation_date: 2013-11-13T21:03:37Z + +[Term] +id: GO:1902500 +name: vacuolar HOPS complex +namespace: cellular_component +def: "Any HOPS complex that is part of a vacuolar membrane." [GOC:TermGenie, PMID:23645161] +synonym: "vacuolar membrane HOPS complex" EXACT [] +is_a: GO:0030897 ! HOPS complex +intersection_of: GO:0030897 ! HOPS complex +intersection_of: part_of GO:0005774 ! vacuolar membrane +relationship: part_of GO:0005774 ! vacuolar membrane +created_by: tb +creation_date: 2013-11-14T00:09:50Z + +[Term] +id: GO:1902501 +name: lysosomal HOPS complex +namespace: cellular_component +def: "Any HOPS complex that is part of a lysosomal membrane." [GOC:TermGenie, PMID:23645161] +synonym: "lysosomal membrane HOPS complex" EXACT [] +is_a: GO:1902500 ! vacuolar HOPS complex +intersection_of: GO:0030897 ! HOPS complex +intersection_of: part_of GO:0005765 ! lysosomal membrane +relationship: part_of GO:0005765 ! lysosomal membrane +created_by: tb +creation_date: 2013-11-14T00:09:59Z + +[Term] +id: GO:1902502 +name: multivesicular body HOPS complex +namespace: cellular_component +def: "Any HOPS complex that is part of a multivesicular body membrane." [GOC:TermGenie, PMID:23645161] +synonym: "multivesicular body membrane HOPS complex" EXACT [] +is_a: GO:0030897 ! HOPS complex +intersection_of: GO:0030897 ! HOPS complex +intersection_of: part_of GO:0032585 ! multivesicular body membrane +relationship: part_of GO:0032585 ! multivesicular body membrane +created_by: tb +creation_date: 2013-11-14T00:10:08Z + +[Term] +id: GO:1902503 +name: adenylyltransferase complex +namespace: cellular_component +def: "A protein complex which is capable of adenylyltransferase activity." [GOC:bhm, GOC:TermGenie, PMID:11713534] +synonym: "ThiF-ThiS complex" RELATED [GOC:dph] +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: bhm +creation_date: 2013-11-14T10:37:25Z + +[Term] +id: GO:1902504 +name: regulation of signal transduction involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint." [GOC:TermGenie, PMID:16299494] +synonym: "regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle +is_a: GO:1902531 ! regulation of intracellular signal transduction +is_a: GO:1904289 ! regulation of mitotic DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +relationship: regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +created_by: vw +creation_date: 2013-11-14T15:26:46Z + +[Term] +id: GO:1902505 +name: negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint." [GOC:TermGenie, PMID:16299494] +synonym: "down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "downregulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "inhibition of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle +is_a: GO:1902504 ! regulation of signal transduction involved in mitotic G2 DNA damage checkpoint +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +is_a: GO:1904290 ! negative regulation of mitotic DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +relationship: negatively_regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +created_by: vw +creation_date: 2013-11-14T15:26:55Z + +[Term] +id: GO:1902506 +name: positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint." [GOC:TermGenie, PMID:16299494] +synonym: "activation of signal transduction involved in mitotic G2 DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "activation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of signal transduction involved in mitotic G2 DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:1902504 ! regulation of signal transduction involved in mitotic G2 DNA damage checkpoint +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +is_a: GO:1904291 ! positive regulation of mitotic DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +relationship: positively_regulates GO:0072434 ! signal transduction involved in mitotic G2 DNA damage checkpoint +created_by: vw +creation_date: 2013-11-14T15:27:04Z + +[Term] +id: GO:1902507 +name: thiazole synthase complex +namespace: cellular_component +def: "A protein complex which is capable of thiazole synthase activity." [GOC:bhm, GOC:TermGenie, PMID:12650933] +is_a: GO:1990228 ! sulfurtransferase complex +created_by: bhm +creation_date: 2013-11-14T16:19:28Z + +[Term] +id: GO:1902508 +name: 2-iminoacetate synthase complex +namespace: cellular_component +def: "A protein complex which is capable of 2-iminoacetate synthase activity." [GOC:bhm, GOC:TermGenie, PMID:12650933] +synonym: "ThiH-ThiG complex" NARROW [GOC:bhm, GOC:dph] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2013-11-14T16:56:44Z + +[Term] +id: GO:1902509 +name: methionine-importing complex +namespace: cellular_component +def: "A protein complex which is capable of methionine-importing activity." [GOC:pr, GOC:TermGenie, PMID:23748165] +synonym: "methionine importer complex" EXACT [] +synonym: "methionine importing complex" EXACT [] +is_a: GO:1902495 ! transmembrane transporter complex +created_by: pr +creation_date: 2013-11-15T10:42:41Z + +[Term] +id: GO:1902510 +name: regulation of apoptotic DNA fragmentation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351, PMID:15723341] +comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). +synonym: "regulation of chromatinolysis" BROAD [GOC:TermGenie] +synonym: "regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "regulation of DNA fragmentation" BROAD [GOC:TermGenie] +synonym: "regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1900117 ! regulation of execution phase of apoptosis +is_a: GO:1903624 ! regulation of DNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006309 ! apoptotic DNA fragmentation +relationship: regulates GO:0006309 ! apoptotic DNA fragmentation +created_by: hjd +creation_date: 2013-11-15T18:28:32Z + +[Term] +id: GO:1902511 +name: negative regulation of apoptotic DNA fragmentation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] +synonym: "down regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "down regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "downregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] +synonym: "inhibition of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1900118 ! negative regulation of execution phase of apoptosis +is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation +is_a: GO:1903625 ! negative regulation of DNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation +relationship: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation +created_by: hjd +creation_date: 2013-11-15T18:28:41Z + +[Term] +id: GO:1902512 +name: positive regulation of apoptotic DNA fragmentation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] +synonym: "activation of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] +synonym: "activation of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] +synonym: "activation of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "up regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] +synonym: "upregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1900119 ! positive regulation of execution phase of apoptosis +is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation +is_a: GO:1903626 ! positive regulation of DNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006309 ! apoptotic DNA fragmentation +relationship: positively_regulates GO:0006309 ! apoptotic DNA fragmentation +created_by: hjd +creation_date: 2013-11-15T18:28:50Z + +[Term] +id: GO:1902513 +name: regulation of organelle transport along microtubule +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087] +synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0060632 ! regulation of microtubule-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072384 ! organelle transport along microtubule +relationship: regulates GO:0072384 ! organelle transport along microtubule +created_by: dph +creation_date: 2013-11-15T20:15:17Z + +[Term] +id: GO:1902514 +name: regulation of calcium ion transmembrane transport via high voltage-gated calcium channel +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel." [GOC:dph, GOC:pg, GOC:TermGenie, PMID:1611048] +synonym: "regulation of generation of L-type calcium current" RELATED [] +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +relationship: regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +created_by: dph +creation_date: 2013-11-16T00:04:42Z + +[Term] +id: GO:1902515 +name: thioredoxin-disulfide reductase complex +namespace: cellular_component +def: "A protein complex which is capable of thioredoxin-disulfide reductase activity." [GOC:bhm, GOC:TermGenie, PMID:10947986] +comment: An example of this is thioredoxin reductase (TrxB) in E. coli [P0A9P4] in PMID:10947986. +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2013-11-26T11:43:38Z + +[Term] +id: GO:1902516 +name: sn-glycerol 3-phosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with sn-glycerol 3-phosphate." [GOC:bhm, GOC:TermGenie, PMID:23013274] +comment: An example of this is UgpB in E. coli [P0AG80] - see PMID:23013274. +is_a: GO:0043168 ! anion binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: bhm +creation_date: 2013-11-27T16:50:55Z + +[Term] +id: GO:1902517 +name: glycerol-3-phosphate-transporting ATPase complex +namespace: cellular_component +def: "A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity." [GOC:bhm, GOC:TermGenie, PMID:23013274] +comment: An example of this is UgpB in E. coli in PMID:23013274. +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +created_by: bhm +creation_date: 2013-11-27T16:53:33Z + +[Term] +id: GO:1902518 +name: response to cyclophosphamide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus." [GOC:dw, GOC:TermGenie, PMID:23648065] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0097327 ! response to antineoplastic agent +created_by: dw +creation_date: 2013-12-02T09:34:08Z + +[Term] +id: GO:1902519 +name: response to docetaxel trihydrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus." [GOC:dw, GOC:TermGenie, PMID:23648065] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to docetaxel" RELATED [] +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: dw +creation_date: 2013-12-02T09:44:04Z + +[Term] +id: GO:1902520 +name: response to doxorubicin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus." [GOC:dw, GOC:TermGenie, PMID:23648065] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1903416 ! response to glycoside +created_by: dw +creation_date: 2013-12-02T09:44:13Z + +[Term] +id: GO:1902521 +name: response to etoposide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus." [GOC:dw, GOC:TermGenie, PMID:23648065] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1904631 ! response to glucoside +created_by: dw +creation_date: 2013-12-02T09:44:22Z + +[Term] +id: GO:1902522 +name: response to 4'-epidoxorubicin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus." [GOC:dw, GOC:TermGenie, PMID:23648065] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +synonym: "response to epirubicin" RELATED [] +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1903416 ! response to glycoside +created_by: dw +creation_date: 2013-12-02T09:44:31Z + +[Term] +id: GO:1902523 +name: positive regulation of protein K63-linked ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination." [GOC:TermGenie, PMID:21931591] +comment: An example is BIRC2 (UniProt ID Q13490) in PMID:21931591. +synonym: "activation of protein K63-linked polyubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein K63-linked ubiquitination" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein K63-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein K63-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein K63-linked ubiquitination" EXACT [GOC:TermGenie] +is_a: GO:1900044 ! regulation of protein K63-linked ubiquitination +is_a: GO:1902916 ! positive regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070534 ! protein K63-linked ubiquitination +relationship: positively_regulates GO:0070534 ! protein K63-linked ubiquitination +created_by: ppm +creation_date: 2013-12-02T09:52:05Z + +[Term] +id: GO:1902524 +name: positive regulation of protein K48-linked ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination." [GOC:TermGenie, PMID:21931591] +comment: An example is BIRC2 (UniProt ID Q13490) in PMID:21931591. +synonym: "activation of protein K48-linked polyubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein K48-linked ubiquitination" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein K48-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein K48-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein K48-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein K48-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein K48-linked ubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein K48-linked polyubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein K48-linked ubiquitination" EXACT [GOC:TermGenie] +is_a: GO:0061945 ! regulation of protein K48-linked ubiquitination +is_a: GO:1902916 ! positive regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070936 ! protein K48-linked ubiquitination +relationship: positively_regulates GO:0070936 ! protein K48-linked ubiquitination +created_by: ppm +creation_date: 2013-12-02T09:56:40Z + +[Term] +id: GO:1902525 +name: regulation of protein monoubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein monoubiquitination." [GOC:TermGenie, PMID:21931591] +synonym: "regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031396 ! regulation of protein ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006513 ! protein monoubiquitination +relationship: regulates GO:0006513 ! protein monoubiquitination +created_by: ppm +creation_date: 2013-12-02T09:58:56Z + +[Term] +id: GO:1902526 +name: negative regulation of protein monoubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination." [GOC:TermGenie, PMID:21931591] +synonym: "down regulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein monoubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of protein monoubiquitinylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein monoubiquitylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031397 ! negative regulation of protein ubiquitination +is_a: GO:1902525 ! regulation of protein monoubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006513 ! protein monoubiquitination +relationship: negatively_regulates GO:0006513 ! protein monoubiquitination +created_by: ppm +creation_date: 2013-12-02T09:59:05Z + +[Term] +id: GO:1902527 +name: positive regulation of protein monoubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein monoubiquitination." [GOC:TermGenie, PMID:21931591] +comment: An example is BIRC2 (UniProt ID Q13490) in PMID:21931591. +synonym: "activation of protein monoubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein monoubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of protein monoubiquitylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein monoubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein monoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein monoubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031398 ! positive regulation of protein ubiquitination +is_a: GO:1902525 ! regulation of protein monoubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006513 ! protein monoubiquitination +relationship: positively_regulates GO:0006513 ! protein monoubiquitination +created_by: ppm +creation_date: 2013-12-02T09:59:21Z + +[Term] +id: GO:1902528 +name: regulation of protein linear polyubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein linear polyubiquitination." [GOC:TermGenie, PMID:21931591] +synonym: "regulation of M1 linkage" NARROW [GOC:TermGenie] +is_a: GO:1902914 ! regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097039 ! protein linear polyubiquitination +relationship: regulates GO:0097039 ! protein linear polyubiquitination +created_by: ppm +creation_date: 2013-12-02T10:03:00Z + +[Term] +id: GO:1902529 +name: negative regulation of protein linear polyubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination." [GOC:TermGenie, PMID:21931591] +synonym: "down regulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "down regulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "down-regulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "downregulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +synonym: "inhibition of M1 linkage" NARROW [GOC:TermGenie] +synonym: "inhibition of protein linear polyubiquitination" NARROW [GOC:TermGenie] +synonym: "negative regulation of M1 linkage" NARROW [GOC:TermGenie] +is_a: GO:1902528 ! regulation of protein linear polyubiquitination +is_a: GO:1902915 ! negative regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097039 ! protein linear polyubiquitination +relationship: negatively_regulates GO:0097039 ! protein linear polyubiquitination +created_by: ppm +creation_date: 2013-12-02T10:03:09Z + +[Term] +id: GO:1902530 +name: positive regulation of protein linear polyubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination." [GOC:TermGenie, PMID:21931591] +comment: An example is BIRC2 (UniProt ID Q13490) in PMID:21931591. +synonym: "activation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "activation of protein linear polyubiquitination" NARROW [GOC:TermGenie] +synonym: "positive regulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "up regulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "up regulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "up-regulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of M1 linkage" NARROW [GOC:TermGenie] +synonym: "upregulation of protein linear polyubiquitination" EXACT [GOC:TermGenie] +is_a: GO:1902528 ! regulation of protein linear polyubiquitination +is_a: GO:1902916 ! positive regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097039 ! protein linear polyubiquitination +relationship: positively_regulates GO:0097039 ! protein linear polyubiquitination +created_by: ppm +creation_date: 2013-12-02T10:03:18Z + +[Term] +id: GO:1902531 +name: regulation of intracellular signal transduction +namespace: biological_process +alt_id: GO:0010627 +def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] +synonym: "regulation of intracellular protein kinase cascade" NARROW [] +synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] +synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035556 ! intracellular signal transduction +relationship: regulates GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2013-12-02T11:32:52Z + +[Term] +id: GO:1902532 +name: negative regulation of intracellular signal transduction +namespace: biological_process +alt_id: GO:0010741 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] +synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie] +synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie] +synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "negative regulation of intracellular protein kinase cascade" EXACT [] +synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035556 ! intracellular signal transduction +relationship: negatively_regulates GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2013-12-02T11:33:01Z + +[Term] +id: GO:1902533 +name: positive regulation of intracellular signal transduction +namespace: biological_process +alt_id: GO:0010740 +def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] +synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie] +synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie] +synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "positive regulation of intracellular protein kinase cascade" NARROW [] +synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035556 ! intracellular signal transduction +relationship: positively_regulates GO:0035556 ! intracellular signal transduction +created_by: bf +creation_date: 2013-12-02T11:33:10Z + +[Term] +id: GO:1902535 +name: multi-organism membrane invagination +namespace: biological_process +def: "A membrane invagination which involves another organism." [GOC:bf, GOC:jl, GOC:TermGenie] +is_a: GO:0010324 ! membrane invagination +is_a: GO:0044803 ! multi-organism membrane organization +created_by: jl +creation_date: 2013-12-02T13:58:43Z + +[Term] +id: GO:1902537 +name: obsolete multi-organism pinocytosis +namespace: biological_process +def: "OBSOLETE. A pinocytosis which involves another organism." [GOC:bf, GOC:jl, GOC:TermGenie] +comment: This term was obsoleted because there is no evidence that this process exists. +is_obsolete: true +created_by: jl +creation_date: 2013-12-02T14:14:46Z + +[Term] +id: GO:1902539 +name: multi-organism macropinocytosis +namespace: biological_process +def: "A macropinocytosis which involves another organism." [GOC:bf, GOC:jl, GOC:TermGenie] +is_a: GO:0044351 ! macropinocytosis +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0044766 ! multi-organism transport +created_by: jl +creation_date: 2013-12-02T14:23:06Z + +[Term] +id: GO:1902541 +name: multi-organism micropinocytosis +namespace: biological_process +def: "A micropinocytosis which involves another organism." [GOC:bf, GOC:jl, GOC:TermGenie] +is_a: GO:0044350 ! micropinocytosis +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0044766 ! multi-organism transport +created_by: bf +creation_date: 2013-12-02T14:26:39Z + +[Term] +id: GO:1902542 +name: regulation of protein localization to mitotic spindle pole body +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body." [GOC:TermGenie, PMID:22809626] +synonym: "regulation of protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:1902363 ! regulation of protein localization to spindle pole body +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902440 ! protein localization to mitotic spindle pole body +relationship: regulates GO:1902440 ! protein localization to mitotic spindle pole body +created_by: al +creation_date: 2013-12-04T13:47:09Z + +[Term] +id: GO:1902543 +name: negative regulation of protein localization to mitotic spindle pole body +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body." [GOC:TermGenie, PMID:22809626] +synonym: "down regulation of protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to mitotic spindle pole body" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to mitotic spindle pole body" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to mitotic spindle pole body" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to mitotic spindle pole body" EXACT [GOC:TermGenie] +is_a: GO:1902364 ! negative regulation of protein localization to spindle pole body +is_a: GO:1902542 ! regulation of protein localization to mitotic spindle pole body +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902440 ! protein localization to mitotic spindle pole body +relationship: negatively_regulates GO:1902440 ! protein localization to mitotic spindle pole body +created_by: al +creation_date: 2013-12-04T13:47:18Z + +[Term] +id: GO:1902544 +name: regulation of DNA N-glycosylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity." [GOC:rph, GOC:TermGenie, PMID:15518571] +synonym: "regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019104 ! DNA N-glycosylase activity +relationship: regulates GO:0019104 ! DNA N-glycosylase activity +created_by: rph +creation_date: 2013-12-04T14:17:54Z + +[Term] +id: GO:1902545 +name: negative regulation of DNA N-glycosylase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity." [GOC:rph, GOC:TermGenie, PMID:15518571] +synonym: "down regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "downregulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "inhibition of DNA glycosylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA N-glycosylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:1902544 ! regulation of DNA N-glycosylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019104 ! DNA N-glycosylase activity +relationship: negatively_regulates GO:0019104 ! DNA N-glycosylase activity +created_by: rph +creation_date: 2013-12-04T14:18:03Z + +[Term] +id: GO:1902546 +name: positive regulation of DNA N-glycosylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity." [GOC:rph, GOC:TermGenie, PMID:15518571] +synonym: "activation of DNA glycosylase activity" NARROW [GOC:TermGenie] +synonym: "activation of DNA N-glycosylase activity" NARROW [GOC:TermGenie] +synonym: "activation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "up regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +synonym: "upregulation of DNA glycosylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA N-glycosylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of endonuclease VIII activity" RELATED [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1902544 ! regulation of DNA N-glycosylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019104 ! DNA N-glycosylase activity +relationship: positively_regulates GO:0019104 ! DNA N-glycosylase activity +created_by: rph +creation_date: 2013-12-04T14:18:12Z + +[Term] +id: GO:1902547 +name: regulation of cellular response to vascular endothelial growth factor stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17895370] +synonym: "regulation of cellular response to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "regulation of cellular response to VEGF" EXACT [GOC:TermGenie] +synonym: "regulation of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "regulation of cellular response to VEGFB" NARROW [GOC:TermGenie] +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +relationship: regulates GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +created_by: rl +creation_date: 2013-12-04T15:14:54Z + +[Term] +id: GO:1902548 +name: negative regulation of cellular response to vascular endothelial growth factor stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17895370] +comment: ADAMTS12 (UniProt ID P58397) in human in PMID:17895370 inhibits the formation of VEGF-induced tubular structures in BAE-1 cells (endothelial cell line). +synonym: "down regulation of cellular response to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to vascular endothelial growth factor stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to VEGF" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "down regulation of cellular response to VEGFB" NARROW [GOC:TermGenie] +synonym: "down-regulation of cellular response to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to vascular endothelial growth factor stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to VEGF" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "down-regulation of cellular response to VEGFB" NARROW [GOC:TermGenie] +synonym: "downregulation of cellular response to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to vascular endothelial growth factor stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to VEGF" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "downregulation of cellular response to VEGFB" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to vascular endothelial growth factor" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to vascular endothelial growth factor stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to VEGF" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to VEGFB" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to VEGF" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to VEGFA" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to VEGFB" NARROW [GOC:TermGenie] +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:1902547 ! regulation of cellular response to vascular endothelial growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +relationship: negatively_regulates GO:0035924 ! cellular response to vascular endothelial growth factor stimulus +created_by: rl +creation_date: 2013-12-04T15:15:03Z + +[Term] +id: GO:1902549 +name: protein localization to Mei2 nuclear dot +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot." [GOC:TermGenie, PMID:23980030] +synonym: "protein localisation in Mei2 nuclear dot" EXACT [GOC:TermGenie] +synonym: "protein localisation to Mei2 nuclear dot" EXACT [GOC:TermGenie] +synonym: "protein localization in Mei2 nuclear dot" EXACT [GOC:TermGenie] +synonym: "protein localization to Mei2 dot" EXACT [] +is_a: GO:0034504 ! protein localization to nucleus +created_by: mah +creation_date: 2013-12-04T16:17:06Z + +[Term] +id: GO:1902550 +name: lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis +namespace: biological_process +def: "Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis." [GOC:cvs, GOC:TermGenie, PMID:22342843] +synonym: "lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0097535 ! lymphoid lineage cell migration into thymus +intersection_of: GO:0097535 ! lymphoid lineage cell migration into thymus +intersection_of: part_of GO:0097536 ! thymus epithelium morphogenesis +relationship: part_of GO:0097536 ! thymus epithelium morphogenesis +created_by: pr +creation_date: 2013-12-04T21:13:33Z + +[Term] +id: GO:1902551 +name: regulation of catalase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of catalase activity." [GOC:TermGenie, PMID:24285797] +synonym: "regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CAT" RELATED [GOC:TermGenie] +synonym: "regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "regulation of optidase activity" EXACT [GOC:TermGenie] +is_a: GO:2000468 ! regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004096 ! catalase activity +relationship: regulates GO:0004096 ! catalase activity +created_by: tb +creation_date: 2013-12-04T21:55:46Z + +[Term] +id: GO:1902552 +name: negative regulation of catalase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity." [GOC:TermGenie, PMID:24285797] +synonym: "down regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CAT" RELATED [GOC:TermGenie] +synonym: "down regulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "down regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CAT" RELATED [GOC:TermGenie] +synonym: "down-regulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "down-regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CAT" RELATED [GOC:TermGenie] +synonym: "downregulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "downregulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of caperase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CAT" RELATED [GOC:TermGenie] +synonym: "inhibition of catalase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of catalase reaction" NARROW [GOC:TermGenie] +synonym: "inhibition of catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of equilase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of optidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CAT" RELATED [GOC:TermGenie] +synonym: "negative regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "negative regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of optidase activity" EXACT [GOC:TermGenie] +is_a: GO:1902551 ! regulation of catalase activity +is_a: GO:2000469 ! negative regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004096 ! catalase activity +relationship: negatively_regulates GO:0004096 ! catalase activity +created_by: tb +creation_date: 2013-12-04T21:55:55Z + +[Term] +id: GO:1902553 +name: positive regulation of catalase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of catalase activity." [GOC:TermGenie, PMID:24285797] +synonym: "activation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of caperase activity" NARROW [GOC:TermGenie] +synonym: "activation of CAT" RELATED [GOC:TermGenie] +synonym: "activation of catalase activity" NARROW [GOC:TermGenie] +synonym: "activation of catalase reaction" NARROW [GOC:TermGenie] +synonym: "activation of catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of equilase activity" NARROW [GOC:TermGenie] +synonym: "activation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "activation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "activation of optidase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CAT" RELATED [GOC:TermGenie] +synonym: "positive regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "positive regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CAT" RELATED [GOC:TermGenie] +synonym: "up regulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "up regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CAT" RELATED [GOC:TermGenie] +synonym: "up-regulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "up-regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of optidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of caperase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CAT" RELATED [GOC:TermGenie] +synonym: "upregulation of catalase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of catalase reaction" EXACT [GOC:TermGenie] +synonym: "upregulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of equilase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of haem catalase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of heme catalase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of manganese catalase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of optidase activity" EXACT [GOC:TermGenie] +is_a: GO:1902551 ! regulation of catalase activity +is_a: GO:2000470 ! positive regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004096 ! catalase activity +relationship: positively_regulates GO:0004096 ! catalase activity +created_by: tb +creation_date: 2013-12-04T21:56:03Z + +[Term] +id: GO:1902554 +name: serine/threonine protein kinase complex +namespace: cellular_component +def: "A protein complex which is capable of protein serine/threonine kinase activity." [GOC:bhm, GOC:TermGenie, PMID:18191223] +comment: An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay). +synonym: "PDR16 complex dimer" RELATED [] +synonym: "PDR16 complex homodimer" RELATED [] +is_a: GO:1902911 ! protein kinase complex +created_by: bhm +creation_date: 2013-12-06T16:06:12Z + +[Term] +id: GO:1902555 +name: endoribonuclease complex +namespace: cellular_component +def: "A protein complex which is capable of endoribonuclease activity." [GOC:bhm, GOC:TermGenie, PMID:18191223] +comment: An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay). +synonym: "Ire1 complex dimer" RELATED [] +synonym: "Ire1 complex homodimer" RELATED [] +synonym: "Ire1 complex homooligomer" RELATED [] +is_a: GO:1905348 ! endonuclease complex +created_by: bhm +creation_date: 2013-12-06T16:09:31Z + +[Term] +id: GO:1902556 +name: phosphatidylinositol transporter complex +namespace: cellular_component +def: "A protein complex which is capable of phosphatidylinositol transporter activity." [GOC:bhm, GOC:TermGenie, PMID:9890948] +comment: An example is PDR16 in S. cerevisiae (UniProt ID P53860) in PMID:9890948 (inferred from direct assay). +synonym: "Ire1 complex dimer" RELATED [] +synonym: "Ire1 complex homodimer" RELATED [] +synonym: "Ire1 complex homooligomer" RELATED [] +is_a: GO:1990351 ! transporter complex +created_by: bhm +creation_date: 2013-12-06T16:12:25Z + +[Term] +id: GO:1902557 +name: 5'-adenylyl sulfate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other." [GOC:TermGenie, PMID:24296033] +comment: An example of this is the YPR011C gene product in S. cerevisiae in PMID:24296033. +is_a: GO:0000295 ! adenine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:1901682 ! sulfur compound transmembrane transporter activity +relationship: part_of GO:1902558 ! 5'-adenylyl sulfate transmembrane transport +created_by: mcc +creation_date: 2013-12-09T23:08:05Z + +[Term] +id: GO:1902558 +name: 5'-adenylyl sulfate transmembrane transport +namespace: biological_process +def: "The process in which 5'-adenylyl sulfate is transported across a membrane." [GOC:TermGenie, PMID:24296033] +synonym: "adenosine 5'-phosphosulfate transmembrane transport" EXACT [PMID:24296033] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0015868 ! purine ribonucleotide transport +is_a: GO:0051503 ! adenine nucleotide transport +is_a: GO:0072348 ! sulfur compound transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: mcc +creation_date: 2013-12-09T23:16:01Z + +[Term] +id: GO:1902559 +name: 3'-phospho-5'-adenylyl sulfate transmembrane transport +namespace: biological_process +def: "The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane." [GOC:TermGenie, PMID:24296033] +synonym: "3'-phosphoadenosine 5'-phosphosulfate transmembrane transport" EXACT [PMID:24296033] +is_a: GO:0046963 ! 3'-phosphoadenosine 5'-phosphosulfate transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: mcc +creation_date: 2013-12-09T23:19:04Z + +[Term] +id: GO:1902560 +name: GMP reductase complex +namespace: cellular_component +def: "An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+)." [GOC:bhm, GOC:TermGenie, PMID:12009299] +comment: An example of this is GMPR2 in human (UniProt Symbol Q9P2T1) in PMID:12009299 (inferred from direct assay). +synonym: "GMP reductase" NARROW [] +synonym: "GMPR1 complex" NARROW [] +synonym: "GMPR2 complex" NARROW [] +synonym: "guanosine monophosphate reductase" NARROW [] +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2013-12-10T11:54:30Z + +[Term] +id: GO:1902561 +name: origin recognition complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex." [GOC:TermGenie, PMID:11717425] +synonym: "ORC assembly" EXACT [GOC:TermGenie] +synonym: "ORC formation" EXACT [GOC:TermGenie] +synonym: "origin of replication recognition complex assembly" EXACT [GOC:TermGenie] +synonym: "origin of replication recognition complex formation" EXACT [GOC:TermGenie] +synonym: "origin recognition complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2013-12-10T12:11:50Z + +[Term] +id: GO:1902562 +name: H4 histone acetyltransferase complex +namespace: cellular_component +def: "A protein complex which is capable of H4 histone acetyltransferase activity." [GOC:bhm, GOC:TermGenie, PMID:23775086] +comment: An example of this is Hpa2 in yeast [Q06592] in PMID:23775086 [IDA]. +synonym: "Hpa3 (homo-)dimer" NARROW [PMID:23775086] +synonym: "Hpa3 complex" NARROW [PMID:23775086] +is_a: GO:0000123 ! histone acetyltransferase complex +created_by: bhm +creation_date: 2013-12-10T14:43:51Z + +[Term] +id: GO:1902563 +name: regulation of neutrophil activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neutrophil activation." [GOC:TermGenie, PMID:17588661] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042119 ! neutrophil activation +relationship: regulates GO:0042119 ! neutrophil activation +created_by: ecu +creation_date: 2013-12-10T15:33:08Z + +[Term] +id: GO:1902564 +name: negative regulation of neutrophil activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation." [GOC:TermGenie, PMID:17588661] +synonym: "down regulation of neutrophil activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of neutrophil activation" EXACT [GOC:TermGenie] +synonym: "downregulation of neutrophil activation" EXACT [GOC:TermGenie] +synonym: "inhibition of neutrophil activation" NARROW [GOC:TermGenie] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:1902563 ! regulation of neutrophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042119 ! neutrophil activation +relationship: negatively_regulates GO:0042119 ! neutrophil activation +created_by: ecu +creation_date: 2013-12-10T15:33:16Z + +[Term] +id: GO:1902565 +name: positive regulation of neutrophil activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil activation." [GOC:TermGenie, PMID:17588661] +synonym: "activation of neutrophil activation" NARROW [GOC:TermGenie] +synonym: "up regulation of neutrophil activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of neutrophil activation" EXACT [GOC:TermGenie] +synonym: "upregulation of neutrophil activation" EXACT [GOC:TermGenie] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:1902563 ! regulation of neutrophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042119 ! neutrophil activation +relationship: positively_regulates GO:0042119 ! neutrophil activation +created_by: ecu +creation_date: 2013-12-10T15:33:26Z + +[Term] +id: GO:1902566 +name: regulation of eosinophil activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eosinophil activation." [GOC:TermGenie, PMID:16254138] +is_a: GO:0002694 ! regulation of leukocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043307 ! eosinophil activation +relationship: regulates GO:0043307 ! eosinophil activation +created_by: ecu +creation_date: 2013-12-10T15:54:35Z + +[Term] +id: GO:1902567 +name: negative regulation of eosinophil activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation." [GOC:TermGenie, PMID:16254138] +synonym: "down regulation of eosinophil activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of eosinophil activation" EXACT [GOC:TermGenie] +synonym: "downregulation of eosinophil activation" EXACT [GOC:TermGenie] +synonym: "inhibition of eosinophil activation" NARROW [GOC:TermGenie] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:1902566 ! regulation of eosinophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043307 ! eosinophil activation +relationship: negatively_regulates GO:0043307 ! eosinophil activation +created_by: ecu +creation_date: 2013-12-10T15:54:43Z + +[Term] +id: GO:1902568 +name: positive regulation of eosinophil activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil activation." [GOC:TermGenie, PMID:16254138] +synonym: "activation of eosinophil activation" NARROW [GOC:TermGenie] +synonym: "up regulation of eosinophil activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of eosinophil activation" EXACT [GOC:TermGenie] +synonym: "upregulation of eosinophil activation" EXACT [GOC:TermGenie] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:1902566 ! regulation of eosinophil activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043307 ! eosinophil activation +relationship: positively_regulates GO:0043307 ! eosinophil activation +created_by: ecu +creation_date: 2013-12-10T15:54:52Z + +[Term] +id: GO:1902569 +name: negative regulation of activation of Janus kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity." [GOC:TermGenie, PMID:16254138] +synonym: "down regulation of activation of JAK1 kinase activity" NARROW [] +synonym: "down regulation of activation of JAK1 protein" NARROW [] +synonym: "down regulation of activation of JAK2 kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of activation of JAK2 protein" NARROW [GOC:TermGenie] +synonym: "down regulation of tyrosine phosphorylation of JAK1 protein" NARROW [] +synonym: "down regulation of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:TermGenie] +synonym: "down-regulation of activation of JAK1 kinase activity" NARROW [] +synonym: "down-regulation of activation of JAK1 protein" NARROW [] +synonym: "down-regulation of activation of JAK2 kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of activation of JAK2 protein" NARROW [GOC:TermGenie] +synonym: "down-regulation of tyrosine phosphorylation of JAK1 protein" NARROW [] +synonym: "down-regulation of tyrosine phosphorylation of JAK2 protein" NARROW [GOC:TermGenie] +synonym: "downregulation of activation of JAK1 kinase activity" NARROW [] +synonym: "downregulation of activation of JAK1 protein" NARROW [] +synonym: "downregulation of activation of JAK2 kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of tyrosine phosphorylation of JAK1 protein" NARROW [] +synonym: "downregulation of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:TermGenie] +synonym: "inhibition of activation of JAK1 kinase activity" NARROW [] +synonym: "inhibition of activation of JAK1 protein" NARROW [] +synonym: "inhibition of activation of JAK2 kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of activation of JAK2 protein" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine phosphorylation of JAK1 protein" NARROW [] +synonym: "inhibition of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:TermGenie] +synonym: "negative regulation of activation of JAK1 protein" NARROW [] +synonym: "negative regulation of activation of JAK2 kinase activity" NARROW [] +synonym: "negative regulation of activation of JAK2 protein" NARROW [GOC:TermGenie] +synonym: "negative regulation of tyrosine phosphorylation of JAK1 protein" NARROW [] +synonym: "negative regulation of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:TermGenie] +is_a: GO:0010533 ! regulation of activation of Janus kinase activity +is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042976 ! activation of Janus kinase activity +relationship: negatively_regulates GO:0042976 ! activation of Janus kinase activity +created_by: ecu +creation_date: 2013-12-10T16:13:20Z + +[Term] +id: GO:1902570 +name: protein localization to nucleolus +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626] +synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie] +is_a: GO:0034504 ! protein localization to nucleus +created_by: mah +creation_date: 2013-12-10T16:25:28Z + +[Term] +id: GO:1902571 +name: regulation of serine-type peptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of serine-type peptidase activity." [GOC:krc, GOC:TermGenie, PMID:20179351] +synonym: "regulation of serine protease activity" NARROW [GOC:TermGenie] +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008236 ! serine-type peptidase activity +relationship: regulates GO:0008236 ! serine-type peptidase activity +created_by: krc +creation_date: 2013-12-10T18:16:58Z + +[Term] +id: GO:1902572 +name: negative regulation of serine-type peptidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity." [GOC:krc, GOC:TermGenie, PMID:20179351] +synonym: "down regulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "down regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "downregulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of serine protease activity" NARROW [GOC:TermGenie] +synonym: "inhibition of serine-type peptidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of serine protease activity" NARROW [GOC:TermGenie] +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:1902571 ! regulation of serine-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008236 ! serine-type peptidase activity +relationship: negatively_regulates GO:0008236 ! serine-type peptidase activity +created_by: krc +creation_date: 2013-12-10T18:17:07Z + +[Term] +id: GO:1902573 +name: positive regulation of serine-type peptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity." [GOC:krc, GOC:TermGenie, PMID:20179351] +synonym: "activation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "activation of serine-type peptidase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of serine protease activity" NARROW [GOC:TermGenie] +synonym: "upregulation of serine-type peptidase activity" EXACT [GOC:TermGenie] +is_a: GO:0010952 ! positive regulation of peptidase activity +is_a: GO:1902571 ! regulation of serine-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008236 ! serine-type peptidase activity +relationship: positively_regulates GO:0008236 ! serine-type peptidase activity +created_by: krc +creation_date: 2013-12-10T18:17:16Z + +[Term] +id: GO:1902574 +name: obsolete negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import." [GOC:TermGenie, PMID:22992726] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: al +creation_date: 2013-12-11T09:43:23Z + +[Term] +id: GO:1902575 +name: protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +namespace: biological_process +def: "Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly." [GOC:al, GOC:TermGenie, PMID:24127216] +synonym: "protein localisation to cell division site involved in constriction ring assembly" NARROW [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring formation" RELATED [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in cytokinesis, actomyosin ring formation" RELATED [GOC:TermGenie] +synonym: "protein localisation to cell division site involved in cytokinesis, contractile ring assembly" RELATED [GOC:TermGenie] +synonym: "protein localization to cell division site involved in constriction ring assembly" NARROW [GOC:TermGenie] +synonym: "protein localization to cell division site involved in contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "protein localization to cell division site involved in cytokinesis, actomyosin contractile ring formation" RELATED [GOC:TermGenie] +synonym: "protein localization to cell division site involved in cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:TermGenie] +synonym: "protein localization to cell division site involved in cytokinesis, actomyosin ring formation" RELATED [GOC:TermGenie] +synonym: "protein localization to cell division site involved in cytokinesis, contractile ring assembly" RELATED [GOC:TermGenie] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0072741 ! protein localization to cell division site +intersection_of: GO:0072741 ! protein localization to cell division site +intersection_of: part_of GO:0000915 ! actomyosin contractile ring assembly +relationship: part_of GO:0000915 ! actomyosin contractile ring assembly +created_by: bf +creation_date: 2013-12-16T10:42:25Z + +[Term] +id: GO:1902576 +name: negative regulation of nuclear cell cycle DNA replication +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication." [GOC:TermGenie, PMID:19033384] +synonym: "down regulation of DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "down regulation of DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "down-regulation of DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "downregulation of DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication involved in S-phase" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "inhibition of DNA replication involved in S phase" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replication involved in S-phase" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA replication during S phase" RELATED [GOC:TermGenie] +synonym: "negative regulation of DNA replication involved in S phase" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA replication involved in S-phase" EXACT [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0033262 ! regulation of nuclear cell cycle DNA replication +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033260 ! nuclear DNA replication +relationship: negatively_regulates GO:0033260 ! nuclear DNA replication +created_by: mah +creation_date: 2013-12-17T14:03:02Z + +[Term] +id: GO:1902577 +name: protein localization to medial cortical node +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a medial cortical node." [GOC:TermGenie, PMID:24127216] +synonym: "protein localisation in medial cortical node" EXACT [GOC:TermGenie] +synonym: "protein localisation to medial cortical node" EXACT [GOC:TermGenie] +synonym: "protein localization in medial cortical node" EXACT [GOC:TermGenie] +is_a: GO:0071574 ! protein localization to medial cortex +created_by: mah +creation_date: 2013-12-17T14:09:28Z + +[Term] +id: GO:1902579 +name: multi-organism localization +namespace: biological_process +def: "A localization which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +synonym: "multi organism localization" EXACT [GOC:TermGenie] +is_a: GO:0051179 ! localization +is_a: GO:0051704 ! multi-organism process +created_by: jl +creation_date: 2013-12-18T13:51:13Z + +[Term] +id: GO:1902581 +name: multi-organism cellular localization +namespace: biological_process +def: "A cellular localization which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +synonym: "multi organism cellular localization" EXACT [GOC:TermGenie] +is_a: GO:0044764 ! multi-organism cellular process +is_a: GO:0051641 ! cellular localization +is_a: GO:1902579 ! multi-organism localization +created_by: jl +creation_date: 2013-12-18T14:04:41Z + +[Term] +id: GO:1902583 +name: obsolete multi-organism intracellular transport +namespace: biological_process +def: "OBSOLETE. An intracellular transport which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "multi organism intracellular transport" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: jl +creation_date: 2013-12-18T14:04:58Z + +[Term] +id: GO:1902584 +name: positive regulation of response to water deprivation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to water deprivation." [GO_REF:0000058, GOC:TermGenie, PMID:24198318] +synonym: "activation of drought tolerance" RELATED [GOC:TermGenie] +synonym: "activation of response to dehydration" NARROW [GOC:TermGenie] +synonym: "activation of response to drought" NARROW [GOC:TermGenie] +synonym: "activation of response to thirst" NARROW [GOC:TermGenie] +synonym: "activation of response to water deprivation" NARROW [GOC:TermGenie] +synonym: "positive regulation of drought tolerance" RELATED [GOC:TermGenie] +synonym: "positive regulation of response to dehydration" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to drought" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to thirst" EXACT [GOC:TermGenie] +synonym: "up regulation of drought tolerance" RELATED [GOC:TermGenie] +synonym: "up regulation of response to dehydration" EXACT [GOC:TermGenie] +synonym: "up regulation of response to drought" EXACT [GOC:TermGenie] +synonym: "up regulation of response to thirst" EXACT [GOC:TermGenie] +synonym: "up regulation of response to water deprivation" EXACT [GOC:TermGenie] +synonym: "up-regulation of drought tolerance" RELATED [GOC:TermGenie] +synonym: "up-regulation of response to dehydration" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to drought" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to thirst" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to water deprivation" EXACT [GOC:TermGenie] +synonym: "upregulation of drought tolerance" RELATED [GOC:TermGenie] +synonym: "upregulation of response to dehydration" EXACT [GOC:TermGenie] +synonym: "upregulation of response to drought" EXACT [GOC:TermGenie] +synonym: "upregulation of response to thirst" EXACT [GOC:TermGenie] +synonym: "upregulation of response to water deprivation" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2000070 ! regulation of response to water deprivation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009414 ! response to water deprivation +relationship: positively_regulates GO:0009414 ! response to water deprivation +created_by: tb +creation_date: 2013-12-19T00:31:58Z + +[Term] +id: GO:1902586 +name: multi-organism intercellular transport +namespace: biological_process +def: "An intercellular transport which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +synonym: "multi organism intercellular transport" EXACT [GOC:TermGenie] +is_a: GO:0044766 ! multi-organism transport +created_by: jl +creation_date: 2013-12-19T13:25:05Z + +[Term] +id: GO:1902588 +name: obsolete multi-organism plasmodesmata-mediated intercellular transport +namespace: biological_process +def: "OBSOLETE. A plasmodesmata-mediated intercellular transport which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "multi organism plasmodesmata-mediated intercellular transport" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: jl +creation_date: 2013-12-19T13:37:53Z + +[Term] +id: GO:1902590 +name: multi-organism organelle organization +namespace: biological_process +def: "An organelle organization which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +synonym: "multi organism organelle organization" EXACT [GOC:TermGenie] +is_a: GO:0006996 ! organelle organization +is_a: GO:0044764 ! multi-organism cellular process +created_by: jl +creation_date: 2013-12-19T15:26:08Z + +[Term] +id: GO:1902592 +name: obsolete multi-organism membrane budding +namespace: biological_process +def: "OBSOLETE. A membrane budding which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +comment: Obsoleted because it was a grouping term for a viral process that was incorrectly under 'multi-organism cellular process'. The children terms have been moved under 'viral process', so that this grouping term is not necessary anymore. +synonym: "multi organism membrane budding" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: jl +creation_date: 2013-12-19T15:26:25Z + +[Term] +id: GO:1902594 +name: multi-organism nuclear import +namespace: biological_process +def: "A nuclear import which involves another organism." [GO_REF:0000089, GOC:jl, GOC:TermGenie] +synonym: "multi organism nuclear import" EXACT [GOC:TermGenie] +is_a: GO:0044766 ! multi-organism transport +is_a: GO:0051170 ! import into nucleus +is_a: GO:1902581 ! multi-organism cellular localization +created_by: jl +creation_date: 2013-12-19T15:26:43Z + +[Term] +id: GO:1902595 +name: regulation of DNA replication origin binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA replication origin binding." [GO_REF:0000059, GOC:TermGenie, PMID:11850415] +synonym: "regulation of ARS binding" NARROW [GOC:TermGenie] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003688 ! DNA replication origin binding +relationship: regulates GO:0003688 ! DNA replication origin binding +created_by: mah +creation_date: 2013-12-19T16:19:39Z + +[Term] +id: GO:1902596 +name: negative regulation of DNA replication origin binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding." [GO_REF:0000059, GOC:TermGenie, PMID:11850415] +synonym: "down regulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "down regulation of DNA replication origin binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "down-regulation of DNA replication origin binding" EXACT [GOC:TermGenie] +synonym: "downregulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "downregulation of DNA replication origin binding" EXACT [GOC:TermGenie] +synonym: "inhibition of ARS binding" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replication origin binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of ARS binding" NARROW [GOC:TermGenie] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:1902595 ! regulation of DNA replication origin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003688 ! DNA replication origin binding +relationship: negatively_regulates GO:0003688 ! DNA replication origin binding +created_by: mah +creation_date: 2013-12-19T16:19:48Z + +[Term] +id: GO:1902597 +name: positive regulation of DNA replication origin binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA replication origin binding." [GO_REF:0000059, GOC:TermGenie, PMID:11850415] +synonym: "activation of ARS binding" NARROW [GOC:TermGenie] +synonym: "activation of DNA replication origin binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "up regulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA replication origin binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "up-regulation of DNA replication origin binding" EXACT [GOC:TermGenie] +synonym: "upregulation of ARS binding" NARROW [GOC:TermGenie] +synonym: "upregulation of DNA replication origin binding" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:1902595 ! regulation of DNA replication origin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003688 ! DNA replication origin binding +relationship: positively_regulates GO:0003688 ! DNA replication origin binding +created_by: mah +creation_date: 2013-12-19T16:19:57Z + +[Term] +id: GO:1902599 +name: sulfathiazole transmembrane transport +namespace: biological_process +alt_id: GO:0015906 +def: "The directed movement of sulfathiazole across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "sulfathiazole transport" BROAD [] +synonym: "sulphathiazole transport" BROAD [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0042886 ! amide transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:0072348 ! sulfur compound transport +created_by: pr +creation_date: 2013-12-20T11:08:28Z + +[Term] +id: GO:1902600 +name: proton transmembrane transport +namespace: biological_process +alt_id: GO:0006818 +alt_id: GO:0015991 +alt_id: GO:0015992 +def: "The directed movement of a proton across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +subset: goslim_pir +synonym: "ATP hydrolysis coupled proton transport" NARROW [] +synonym: "hydrogen ion transmembrane transport" EXACT [] +synonym: "hydrogen ion transport" RELATED [] +synonym: "hydrogen transmembrane transport" EXACT [] +synonym: "hydrogen transport" BROAD [] +synonym: "passive proton transport, down the electrochemical gradient" NARROW [] +synonym: "proton transmembrane transport" EXACT [] +synonym: "proton transport" BROAD [] +is_a: GO:0015672 ! monovalent inorganic cation transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:08:37Z + +[Term] +id: GO:1902601 +name: silver ion transmembrane transport +namespace: biological_process +def: "The directed movement of silver ion across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "silver transmembrane transport" BROAD [] +is_a: GO:0098660 ! inorganic ion transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:08:46Z + +[Term] +id: GO:1902602 +name: aluminum ion transmembrane transport +namespace: biological_process +def: "The process in which an aluminium ion is transported across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "aluminium ion transmembrane transport" EXACT [] +synonym: "aluminium transmembrane transport" BROAD [] +synonym: "aluminum transmembrane transport" BROAD [] +is_a: GO:0098660 ! inorganic ion transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:09:01Z + +[Term] +id: GO:1902603 +name: carnitine transmembrane transport +namespace: biological_process +def: "The directed movement of carnitine across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +is_a: GO:0015879 ! carnitine transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:09:11Z + +[Term] +id: GO:1902604 +name: p-aminobenzoyl-glutamate transmembrane transport +namespace: biological_process +def: "The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "N-(4-aminobenzoyl)-L-glutamate transmembrane transport" EXACT [] +is_a: GO:0015814 ! p-aminobenzoyl-glutamate transport +is_a: GO:0035442 ! dipeptide transmembrane transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: pr +creation_date: 2013-12-20T11:09:20Z + +[Term] +id: GO:1902605 +name: heterotrimeric G-protein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex." [GO_REF:0000079, GOC:dph, GOC:TermGenie, PMID:23637185] +synonym: "heterotrimeric G-protein complex formation" EXACT [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase activity assembly" RELATED [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase activity formation" RELATED [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, alpha-subunit assembly" NARROW [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, alpha-subunit formation" NARROW [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, beta-subunit assembly" NARROW [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, beta-subunit formation" NARROW [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, gamma-subunit assembly" NARROW [GOC:TermGenie] +synonym: "heterotrimeric G-protein GTPase, gamma-subunit formation" NARROW [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: dph +creation_date: 2013-12-30T16:31:28Z + +[Term] +id: GO:1902606 +name: regulation of large conductance calcium-activated potassium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:23407708] +synonym: "regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +relationship: regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +created_by: sl +creation_date: 2014-01-02T18:51:03Z + +[Term] +id: GO:1902607 +name: negative regulation of large conductance calcium-activated potassium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:23407708] +synonym: "down regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "down regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "down regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "down-regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "down-regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "downregulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "downregulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "downregulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "inhibition of BK calcium-activated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of BK channel activity" RELATED [GOC:TermGenie] +synonym: "inhibition of BK KCa channels" NARROW [GOC:TermGenie] +synonym: "inhibition of large conductance calcium-activated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of large conductance KCa channels" NARROW [GOC:TermGenie] +synonym: "negative regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "negative regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity +is_a: GO:1902606 ! regulation of large conductance calcium-activated potassium channel activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +relationship: negatively_regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +created_by: sl +creation_date: 2014-01-02T18:51:12Z + +[Term] +id: GO:1902608 +name: positive regulation of large conductance calcium-activated potassium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:23407708] +synonym: "activation of BK calcium-activated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "activation of BK KCa channels" NARROW [GOC:TermGenie] +synonym: "activation of large conductance calcium-activated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of large conductance KCa channels" NARROW [GOC:TermGenie] +synonym: "positive regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "positive regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "up regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "up regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "up regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "up-regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "up-regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of large conductance KCa channels" EXACT [GOC:TermGenie] +synonym: "upregulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of BK channel activity" RELATED [GOC:TermGenie] +synonym: "upregulation of BK KCa channels" EXACT [GOC:TermGenie] +synonym: "upregulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of large conductance KCa channels" EXACT [GOC:TermGenie] +is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity +is_a: GO:1902606 ! regulation of large conductance calcium-activated potassium channel activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +relationship: positively_regulates GO:0060072 ! large conductance calcium-activated potassium channel activity +created_by: sl +creation_date: 2014-01-02T18:51:21Z + +[Term] +id: GO:1902609 +name: (R)-2-hydroxy-alpha-linolenic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid." [GO_REF:0000068, GOC:TermGenie, PMID:24214535] +synonym: "(R)-2-hydroxy-alpha-linolenic acid anabolism" EXACT [GOC:TermGenie] +synonym: "(R)-2-hydroxy-alpha-linolenic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "(R)-2-hydroxy-alpha-linolenic acid formation" EXACT [GOC:TermGenie] +synonym: "(R)-2-hydroxy-alpha-linolenic acid synthesis" EXACT [GOC:TermGenie] +synonym: "2-hydroxy-octadecatrienoic acid biosynthesis" BROAD [] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +created_by: tb +creation_date: 2014-01-08T01:14:03Z + +[Term] +id: GO:1902610 +name: response to N-phenylthiourea +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus." [GO_REF:0000071, GOC:rjd, GOC:TermGenie, PMID:24006265] +is_a: GO:0010033 ! response to organic substance +created_by: rjd +creation_date: 2014-01-08T01:57:49Z + +[Term] +id: GO:1902611 +name: cellular response to N-phenylthiourea +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus." [GO_REF:0000071, GOC:rjd, GOC:TermGenie, PMID:24006265] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1902610 ! response to N-phenylthiourea +created_by: rjd +creation_date: 2014-01-08T01:57:58Z + +[Term] +id: GO:1902612 +name: regulation of anti-Mullerian hormone signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23624077] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +relationship: regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +created_by: hjd +creation_date: 2014-01-09T15:39:30Z + +[Term] +id: GO:1902613 +name: negative regulation of anti-Mullerian hormone signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23624077] +synonym: "down regulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of anti-Mullerian hormone signaling pathway" NARROW [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902612 ! regulation of anti-Mullerian hormone signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +relationship: negatively_regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +created_by: hjd +creation_date: 2014-01-09T15:39:39Z + +[Term] +id: GO:1902614 +name: positive regulation of anti-Mullerian hormone signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23624077] +synonym: "activation of anti-Mullerian hormone signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of anti-Mullerian hormone signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902612 ! regulation of anti-Mullerian hormone signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +relationship: positively_regulates GO:1990262 ! anti-Mullerian hormone signaling pathway +created_by: hjd +creation_date: 2014-01-09T15:39:48Z + +[Term] +id: GO:1902615 +name: immune response involved in response to exogenous dsRNA +namespace: biological_process +def: "Any immune response that is involved in response to exogenous dsRNA." [GO_REF:0000060, GOC:pg, GOC:TermGenie, PMID:21266579] +synonym: "immune response involved in response to exogenous double-stranded RNA" EXACT [GOC:TermGenie] +synonym: "immune response involved in response to viral dsRNA" NARROW [GOC:TermGenie] +is_a: GO:0006955 ! immune response +intersection_of: GO:0006955 ! immune response +intersection_of: part_of GO:0043330 ! response to exogenous dsRNA +relationship: part_of GO:0043330 ! response to exogenous dsRNA +created_by: tb +creation_date: 2014-01-10T01:29:25Z + +[Term] +id: GO:1902616 +name: acyl carnitine transmembrane transport +namespace: biological_process +def: "The process in which acyl carnitine is transported across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie] +synonym: "O-acylcarnitine transmembrane transport" EXACT [] +is_a: GO:0006844 ! acyl carnitine transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: pr +creation_date: 2014-01-10T11:07:30Z + +[Term] +id: GO:1902617 +name: response to fluoride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus." [GO_REF:0000071, GOC:kmv, GOC:TermGenie, PMID:8138152] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010035 ! response to inorganic substance +created_by: kmv +creation_date: 2014-01-10T19:41:49Z + +[Term] +id: GO:1902618 +name: cellular response to fluoride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus." [GO_REF:0000071, GOC:kmv, GOC:TermGenie, PMID:8138152] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:1902617 ! response to fluoride +created_by: kmv +creation_date: 2014-01-10T19:41:58Z + +[Term] +id: GO:1902619 +name: regulation of microtubule minus-end binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule minus-end binding." [GO_REF:0000059, GOC:di, GOC:TermGenie, PMID:22939623] +is_a: GO:1904526 ! regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051011 ! microtubule minus-end binding +relationship: regulates GO:0051011 ! microtubule minus-end binding +created_by: tb +creation_date: 2014-01-14T22:17:16Z + +[Term] +id: GO:1902620 +name: positive regulation of microtubule minus-end binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding." [GO_REF:0000059, GOC:di, GOC:TermGenie, PMID:22939623] +synonym: "activation of microtubule minus-end binding" NARROW [GOC:TermGenie] +synonym: "up regulation of microtubule minus-end binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule minus-end binding" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule minus-end binding" EXACT [GOC:TermGenie] +is_a: GO:1902619 ! regulation of microtubule minus-end binding +is_a: GO:1904528 ! positive regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051011 ! microtubule minus-end binding +relationship: positively_regulates GO:0051011 ! microtubule minus-end binding +created_by: tb +creation_date: 2014-01-14T22:17:25Z + +[Term] +id: GO:1902621 +name: actomyosin contractile ring disassembly +namespace: biological_process +def: "The disaggregation of an actomyosin contractile ring into its constituent components." [GO_REF:0000079, GOC:TermGenie, PMID:14602073, PMID:22891673] +synonym: "actomyosin ring disassembly" RELATED [GOC:TermGenie] +synonym: "CAR disassembly" EXACT [GOC:TermGenie] +synonym: "constriction ring disassembly" RELATED [GOC:TermGenie] +synonym: "contractile actomyosin ring disassembly" EXACT [GOC:TermGenie] +synonym: "cytokinetic ring disassembly" RELATED [GOC:TermGenie] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0032506 ! cytokinetic process +is_a: GO:0044837 ! actomyosin contractile ring organization +created_by: mah +creation_date: 2014-01-15T09:27:26Z + +[Term] +id: GO:1902622 +name: regulation of neutrophil migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neutrophil migration." [GO_REF:0000058, GOC:TermGenie, PMID:1826836] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990266 ! neutrophil migration +relationship: regulates GO:1990266 ! neutrophil migration +created_by: sl +creation_date: 2014-01-15T18:58:39Z + +[Term] +id: GO:1902623 +name: negative regulation of neutrophil migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration." [GO_REF:0000058, GOC:TermGenie, PMID:1826836] +synonym: "down regulation of neutrophil migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of neutrophil migration" EXACT [GOC:TermGenie] +synonym: "downregulation of neutrophil migration" EXACT [GOC:TermGenie] +synonym: "inhibition of neutrophil migration" NARROW [GOC:TermGenie] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:1902622 ! regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990266 ! neutrophil migration +relationship: negatively_regulates GO:1990266 ! neutrophil migration +created_by: sl +creation_date: 2014-01-15T18:58:49Z + +[Term] +id: GO:1902624 +name: positive regulation of neutrophil migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil migration." [GO_REF:0000058, GOC:TermGenie, PMID:1826836] +synonym: "activation of neutrophil migration" NARROW [GOC:TermGenie] +synonym: "up regulation of neutrophil migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of neutrophil migration" EXACT [GOC:TermGenie] +synonym: "upregulation of neutrophil migration" EXACT [GOC:TermGenie] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:1902622 ! regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990266 ! neutrophil migration +relationship: positively_regulates GO:1990266 ! neutrophil migration +created_by: sl +creation_date: 2014-01-15T18:58:58Z + +[Term] +id: GO:1902625 +name: obsolete negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion." [GO_REF:0000063, GOC:TermGenie, PMID:9671458] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: mah +creation_date: 2014-01-16T13:52:24Z + +[Term] +id: GO:1902626 +name: assembly of large subunit precursor of preribosome +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome." [GO_REF:0000079, GOC:di, GOC:TermGenie, PMID:22735702] +synonym: "66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +created_by: tb +creation_date: 2014-01-16T19:38:05Z + +[Term] +id: GO:1902627 +name: regulation of assembly of large subunit precursor of preribosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22735702] +synonym: "regulation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "regulation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "regulation of preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902626 ! assembly of large subunit precursor of preribosome +relationship: regulates GO:1902626 ! assembly of large subunit precursor of preribosome +created_by: tb +creation_date: 2014-01-16T22:11:45Z + +[Term] +id: GO:1902628 +name: positive regulation of assembly of large subunit precursor of preribosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22735702] +synonym: "activation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "activation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "activation of assembly of large subunit precursor of preribosome" NARROW [GOC:TermGenie] +synonym: "activation of preribosome, large subunit precursor formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +synonym: "up regulation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "up regulation of assembly of large subunit precursor of preribosome" EXACT [GOC:TermGenie] +synonym: "up regulation of preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of assembly of large subunit precursor of preribosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +synonym: "upregulation of 66S preribosome assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of 66S preribosome formation" NARROW [GOC:TermGenie] +synonym: "upregulation of assembly of large subunit precursor of preribosome" EXACT [GOC:TermGenie] +synonym: "upregulation of preribosome, large subunit precursor formation" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1902627 ! regulation of assembly of large subunit precursor of preribosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902626 ! assembly of large subunit precursor of preribosome +relationship: positively_regulates GO:1902626 ! assembly of large subunit precursor of preribosome +created_by: tb +creation_date: 2014-01-16T22:11:55Z + +[Term] +id: GO:1902629 +name: regulation of mRNA stability involved in cellular response to UV +namespace: biological_process +def: "Any regulation of mRNA stability that is involved in cellular response to UV." [GO_REF:0000060, GOC:TermGenie, PMID:10954610] +synonym: "regulation of mRNA stability involved in cellular response to ultraviolet light stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA stability involved in cellular response to ultraviolet radiation stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA stability involved in cellular response to UV light stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA stability involved in cellular response to UV radiation stimulus" EXACT [GOC:TermGenie] +is_a: GO:0043488 ! regulation of mRNA stability +intersection_of: GO:0043488 ! regulation of mRNA stability +intersection_of: part_of GO:0034644 ! cellular response to UV +relationship: part_of GO:0034644 ! cellular response to UV +created_by: mah +creation_date: 2014-01-17T12:23:38Z + +[Term] +id: GO:1902630 +name: regulation of membrane hyperpolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane hyperpolarization." [GO_REF:0000058, GOC:TermGenie, PMID:23223304] +is_a: GO:0042391 ! regulation of membrane potential +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060081 ! membrane hyperpolarization +relationship: regulates GO:0060081 ! membrane hyperpolarization +created_by: krc +creation_date: 2014-01-17T18:27:56Z + +[Term] +id: GO:1902631 +name: negative regulation of membrane hyperpolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization." [GO_REF:0000058, GOC:TermGenie, PMID:23223304] +synonym: "down regulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane hyperpolarization" NARROW [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1902630 ! regulation of membrane hyperpolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060081 ! membrane hyperpolarization +relationship: negatively_regulates GO:0060081 ! membrane hyperpolarization +created_by: krc +creation_date: 2014-01-17T18:28:05Z + +[Term] +id: GO:1902632 +name: positive regulation of membrane hyperpolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization." [GO_REF:0000058, GOC:TermGenie, PMID:23223304] +synonym: "activation of membrane hyperpolarization" NARROW [GOC:TermGenie] +synonym: "up regulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane hyperpolarization" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1902630 ! regulation of membrane hyperpolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060081 ! membrane hyperpolarization +relationship: positively_regulates GO:0060081 ! membrane hyperpolarization +created_by: krc +creation_date: 2014-01-17T18:28:14Z + +[Term] +id: GO:1902633 +name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:22562153] +comment: Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name. +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +created_by: di +creation_date: 2014-01-18T00:34:27Z + +[Term] +id: GO:1902634 +name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:22562153] +comment: Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name. +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0031161 ! phosphatidylinositol catabolic process +is_a: GO:1902633 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process +created_by: di +creation_date: 2014-01-18T00:34:36Z + +[Term] +id: GO:1902635 +name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:22562153] +comment: Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name. +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006661 ! phosphatidylinositol biosynthetic process +is_a: GO:1902633 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process +created_by: di +creation_date: 2014-01-18T00:34:45Z + +[Term] +id: GO:1902636 +name: kinociliary basal body +namespace: cellular_component +def: "A ciliary basal body that is part of a kinocilium." [GO_REF:0000064, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:15855039, PMID:15882574] +synonym: "cilial basal body of kinocilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of kinocilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of kinocilium" EXACT [GOC:TermGenie] +synonym: "kinocilial basal body" EXACT [] +synonym: "kinocilium basal body" EXACT [] +synonym: "kinocilium ciliary basal body" EXACT [] +synonym: "microtubule basal body of kinocilium" EXACT [GOC:TermGenie] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0060091 ! kinocilium +relationship: part_of GO:0060091 ! kinocilium +created_by: pr +creation_date: 2014-01-20T13:48:45Z + +[Term] +id: GO:1902637 +name: neural crest cell differentiation involved in thymus development +namespace: biological_process +def: "Any neural crest cell differentiation that is involved in thymus development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317, PMID:18292542] +is_a: GO:0014033 ! neural crest cell differentiation +intersection_of: GO:0014033 ! neural crest cell differentiation +intersection_of: part_of GO:0048538 ! thymus development +relationship: part_of GO:0048538 ! thymus development +created_by: pr +creation_date: 2014-01-21T10:03:20Z + +[Term] +id: GO:1902638 +name: neural crest cell differentiation involved in parathyroid gland development +namespace: biological_process +def: "Any neural crest cell differentiation that is involved in parathyroid gland development." [GO_REF:0000060, GOC:nhn, GOC:TermGenie, PMID:15741317] +is_a: GO:0014033 ! neural crest cell differentiation +intersection_of: GO:0014033 ! neural crest cell differentiation +intersection_of: part_of GO:0060017 ! parathyroid gland development +relationship: part_of GO:0060017 ! parathyroid gland development +created_by: pr +creation_date: 2014-01-21T10:03:29Z + +[Term] +id: GO:1902639 +name: propan-2-ol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving propan-2-ol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16346237] +synonym: "Isopropanol metabolic process" EXACT [] +synonym: "Isopropyl alcohol metabolic process" EXACT [] +synonym: "propan-2-ol metabolism" EXACT [GOC:TermGenie] +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: tt +creation_date: 2014-01-21T13:57:13Z + +[Term] +id: GO:1902640 +name: propan-2-ol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of propan-2-ol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16346237] +synonym: "Isopropanol biosynthetic process" EXACT [] +synonym: "Isopropyl alcohol biosynthetic process" EXACT [] +synonym: "propan-2-ol anabolism" EXACT [GOC:TermGenie] +synonym: "propan-2-ol biosynthesis" EXACT [GOC:TermGenie] +synonym: "propan-2-ol formation" EXACT [GOC:TermGenie] +synonym: "propan-2-ol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1902639 ! propan-2-ol metabolic process +is_a: GO:1902653 ! secondary alcohol biosynthetic process +created_by: tt +creation_date: 2014-01-21T13:57:22Z + +[Term] +id: GO:1902641 +name: regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0060696 ! regulation of phospholipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +relationship: regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +created_by: di +creation_date: 2014-01-21T17:54:14Z + +[Term] +id: GO:1902642 +name: negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:1902641 ! regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +is_a: GO:1903726 ! negative regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +relationship: negatively_regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +created_by: di +creation_date: 2014-01-21T17:54:23Z + +[Term] +id: GO:1902643 +name: positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0060697 ! positive regulation of phospholipid catabolic process +is_a: GO:1902641 ! regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +relationship: positively_regulates GO:1902634 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process +created_by: di +creation_date: 2014-01-21T17:54:32Z + +[Term] +id: GO:1902644 +name: tertiary alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving tertiary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:11288200] +synonym: "tertiary alcohol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006066 ! alcohol metabolic process +created_by: tt +creation_date: 2014-01-21T17:53:53Z + +[Term] +id: GO:1902645 +name: tertiary alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of tertiary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:11288200] +synonym: "tertiary alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "tertiary alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "tertiary alcohol formation" EXACT [GOC:TermGenie] +synonym: "tertiary alcohol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:1902644 ! tertiary alcohol metabolic process +created_by: tt +creation_date: 2014-01-21T17:54:02Z + +[Term] +id: GO:1902646 +name: regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010511 ! regulation of phosphatidylinositol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +relationship: regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +created_by: di +creation_date: 2014-01-21T17:57:57Z + +[Term] +id: GO:1902647 +name: negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010512 ! negative regulation of phosphatidylinositol biosynthetic process +is_a: GO:1902646 ! regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +relationship: negatively_regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +created_by: di +creation_date: 2014-01-21T17:58:06Z + +[Term] +id: GO:1902648 +name: positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22562153] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" NARROW [GOC:TermGenie] +synonym: "activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010513 ! positive regulation of phosphatidylinositol biosynthetic process +is_a: GO:1902646 ! regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +relationship: positively_regulates GO:1902635 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process +created_by: di +creation_date: 2014-01-21T17:58:15Z + +[Term] +id: GO:1902649 +name: regulation of histone H2A-H2B dimer displacement +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22199252] +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001208 ! histone H2A-H2B dimer displacement +relationship: regulates GO:0001208 ! histone H2A-H2B dimer displacement +created_by: di +creation_date: 2014-01-21T18:19:04Z + +[Term] +id: GO:1902650 +name: negative regulation of histone H2A-H2B dimer displacement +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22199252] +synonym: "down regulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H2A-H2B dimer displacement" NARROW [GOC:TermGenie] +is_a: GO:1902649 ! regulation of histone H2A-H2B dimer displacement +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001208 ! histone H2A-H2B dimer displacement +relationship: negatively_regulates GO:0001208 ! histone H2A-H2B dimer displacement +created_by: di +creation_date: 2014-01-21T18:19:14Z + +[Term] +id: GO:1902651 +name: positive regulation of histone H2A-H2B dimer displacement +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:22199252] +synonym: "activation of histone H2A-H2B dimer displacement" NARROW [GOC:TermGenie] +synonym: "up regulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H2A-H2B dimer displacement" EXACT [GOC:TermGenie] +is_a: GO:1902649 ! regulation of histone H2A-H2B dimer displacement +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001208 ! histone H2A-H2B dimer displacement +relationship: positively_regulates GO:0001208 ! histone H2A-H2B dimer displacement +created_by: di +creation_date: 2014-01-21T18:19:23Z + +[Term] +id: GO:1902652 +name: secondary alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving secondary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:11288200] +synonym: "secondary alcohol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006066 ! alcohol metabolic process +created_by: tt +creation_date: 2014-01-22T10:14:52Z + +[Term] +id: GO:1902653 +name: secondary alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of secondary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:11288200] +synonym: "secondary alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "secondary alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "secondary alcohol formation" EXACT [GOC:TermGenie] +synonym: "secondary alcohol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:1902652 ! secondary alcohol metabolic process +created_by: tt +creation_date: 2014-01-22T10:15:02Z + +[Term] +id: GO:1902654 +name: aromatic primary alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving aromatic primary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:19219878] +synonym: "aromatic primary alcohol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: tt +creation_date: 2014-01-22T10:47:21Z + +[Term] +id: GO:1902655 +name: aromatic primary alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of aromatic primary alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:19219878] +synonym: "aromatic primary alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "aromatic primary alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "aromatic primary alcohol formation" EXACT [GOC:TermGenie] +synonym: "aromatic primary alcohol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1902654 ! aromatic primary alcohol metabolic process +created_by: tt +creation_date: 2014-01-22T10:47:30Z + +[Term] +id: GO:1902656 +name: calcium ion import into cytosol +namespace: biological_process +def: "The directed movement of calcium ion into a cytosol." [GO_REF:0000075, GOC:TermGenie, GOC:vw] +synonym: "calcium import into cytosol" BROAD [] +is_a: GO:0060402 ! calcium ion transport into cytosol +is_a: GO:0070509 ! calcium ion import +created_by: pr +creation_date: 2014-01-22T13:41:11Z + +[Term] +id: GO:1902657 +name: protein localization to prospore membrane +namespace: biological_process +alt_id: GO:0072693 +alt_id: GO:1902658 +def: "A process in which a protein is transported to, or maintained in, a location within a prospore membrane." [GO_REF:0000087, GOC:dph, GOC:TermGenie, PMID:24036347] +synonym: "establishment of protein localisation in prospore membrane" RELATED [GOC:TermGenie] +synonym: "establishment of protein localisation to prospore membrane" RELATED [GOC:TermGenie] +synonym: "establishment of protein localization in prospore membrane" RELATED [GOC:TermGenie] +synonym: "establishment of protein localization to prospore membrane" RELATED [] +synonym: "protein localisation in prospore membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to prospore membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in prospore membrane" EXACT [GOC:TermGenie] +synonym: "protein targeting to ascospore-type prospore membrane" RELATED [GOC:mah] +synonym: "protein targeting to forespore membrane" RELATED [GOC:mah] +synonym: "protein targeting to FSM" RELATED [GOC:mah] +synonym: "protein targeting to prospore membrane" RELATED [] +synonym: "protein-prospore membrane targeting" RELATED [GOC:mah] +is_a: GO:0072657 ! protein localization to membrane +created_by: dph +creation_date: 2011-11-16T11:28:26Z + +[Term] +id: GO:1902659 +name: regulation of glucose mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24277933] +synonym: "regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010255 ! glucose mediated signaling pathway +relationship: regulates GO:0010255 ! glucose mediated signaling pathway +created_by: di +creation_date: 2014-01-28T17:54:21Z + +[Term] +id: GO:1902660 +name: negative regulation of glucose mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24277933] +synonym: "down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902659 ! regulation of glucose mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010255 ! glucose mediated signaling pathway +relationship: negatively_regulates GO:0010255 ! glucose mediated signaling pathway +created_by: di +creation_date: 2014-01-28T17:54:31Z + +[Term] +id: GO:1902661 +name: positive regulation of glucose mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24277933] +synonym: "activation of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "positive regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "up regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902659 ! regulation of glucose mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010255 ! glucose mediated signaling pathway +relationship: positively_regulates GO:0010255 ! glucose mediated signaling pathway +created_by: di +creation_date: 2014-01-28T17:54:47Z + +[Term] +id: GO:1902662 +name: regulation of peptidyl-L-cysteine S-palmitoylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] +synonym: "regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +is_a: GO:1903059 ! regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +relationship: regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +created_by: mm2 +creation_date: 2014-01-29T11:33:09Z + +[Term] +id: GO:1902663 +name: negative regulation of peptidyl-L-cysteine S-palmitoylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] +synonym: "down regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidyl-cysteine S-palmitoylation" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidyl-L-cysteine S-palmitoylation" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "negative regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +is_a: GO:1902662 ! regulation of peptidyl-L-cysteine S-palmitoylation +is_a: GO:1903060 ! negative regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +relationship: negatively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +created_by: mm2 +creation_date: 2014-01-29T11:33:19Z + +[Term] +id: GO:1902664 +name: positive regulation of peptidyl-L-cysteine S-palmitoylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] +synonym: "activation of peptidyl-cysteine S-palmitoylation" NARROW [GOC:TermGenie] +synonym: "activation of peptidyl-L-cysteine S-palmitoylation" NARROW [GOC:TermGenie] +synonym: "activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" NARROW [GOC:TermGenie] +synonym: "positive regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] +is_a: GO:1902662 ! regulation of peptidyl-L-cysteine S-palmitoylation +is_a: GO:1903061 ! positive regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +relationship: positively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation +created_by: mm2 +creation_date: 2014-01-29T11:33:28Z + +[Term] +id: GO:1902665 +name: response to isobutanol +namespace: biological_process +alt_id: GO:1990337 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:24014527] +synonym: "process resulting in tolerance to isobutanol" NARROW [] +synonym: "response to 2-methylpropan-1-ol" EXACT [GOC:mengo_curators] +is_a: GO:0097305 ! response to alcohol + +[Term] +id: GO:1902666 +name: obsolete protein localization to Mmi1 nuclear focus complex +namespace: biological_process +def: "OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex." [GO_REF:0000087, GOC:TermGenie, PMID:23980030] +comment: This term was obsoleted because there is no evidence that this process exists (no factor mediates the localization of proteins to Mmi1 nuclear foci) +synonym: "protein localisation in Mmi1 nuclear focus complex" EXACT [GOC:TermGenie] +synonym: "protein localisation to Mmi1 nuclear focus complex" EXACT [GOC:TermGenie] +synonym: "protein localization in Mmi1 nuclear focus complex" EXACT [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19063 xsd:anyURI +is_obsolete: true +created_by: mah +creation_date: 2014-01-30T10:42:17Z + +[Term] +id: GO:1902667 +name: regulation of axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axon guidance." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23006775] +synonym: "regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "regulation of axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:0050770 ! regulation of axonogenesis +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007411 ! axon guidance +relationship: regulates GO:0007411 ! axon guidance +created_by: hjd +creation_date: 2014-01-31T18:50:10Z + +[Term] +id: GO:1902668 +name: negative regulation of axon guidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23006775] +synonym: "down regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "down regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "down regulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "down-regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "down-regulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "downregulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "downregulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "downregulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "inhibition of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "inhibition of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of axon pathfinding" NARROW [GOC:TermGenie] +synonym: "negative regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "negative regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "negative regulation of axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:0050771 ! negative regulation of axonogenesis +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007411 ! axon guidance +relationship: negatively_regulates GO:0007411 ! axon guidance +created_by: hjd +creation_date: 2014-01-31T18:50:19Z + +[Term] +id: GO:1902669 +name: positive regulation of axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axon guidance." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:23006775] +synonym: "activation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "activation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "activation of axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of axon pathfinding" NARROW [GOC:TermGenie] +synonym: "positive regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "positive regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "positive regulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "up regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "up regulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "up-regulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "up-regulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of axon pathfinding" EXACT [GOC:TermGenie] +synonym: "upregulation of axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "upregulation of axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "upregulation of axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:0050772 ! positive regulation of axonogenesis +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007411 ! axon guidance +relationship: positively_regulates GO:0007411 ! axon guidance +created_by: hjd +creation_date: 2014-01-31T18:50:29Z + +[Term] +id: GO:1902670 +name: carbon dioxide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with carbon dioxide." [GO_REF:0000067, GOC:bhm, GOC:TermGenie, PMID:15491402] +synonym: "CO2 binding" EXACT [] +is_a: GO:0008144 ! drug binding +created_by: bhm +creation_date: 2014-02-04T10:38:41Z + +[Term] +id: GO:1902671 +name: left anterior basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of left anterior cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left anterior flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left anterior cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left anterior flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left anterior cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left anterior flagellum" EXACT [GOC:TermGenie] +synonym: "left anterior flagellum ciliary basal body" EXACT [] +synonym: "microtubule basal body of left anterior cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left anterior flagellum" EXACT [GOC:TermGenie] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097554 ! left anterior flagellum +relationship: part_of GO:0097554 ! left anterior flagellum +created_by: pr +creation_date: 2014-02-05T14:28:44Z + +[Term] +id: GO:1902672 +name: right anterior basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of right anterior cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right anterior flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right anterior cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right anterior flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right anterior cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right anterior flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right anterior cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right anterior flagellum" EXACT [GOC:TermGenie] +synonym: "right anterior flagellum ciliary basal body" EXACT [] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097555 ! right anterior flagellum +relationship: part_of GO:0097555 ! right anterior flagellum +created_by: pr +creation_date: 2014-02-05T14:46:26Z + +[Term] +id: GO:1902673 +name: left posteriolateral basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of left posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "left posteriolateral flagellum ciliary basal body" EXACT [] +synonym: "microtubule basal body of left posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left posterolateral flagellum" EXACT [GOC:TermGenie] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097556 ! left posteriolateral flagellum +relationship: part_of GO:0097556 ! left posteriolateral flagellum +created_by: pr +creation_date: 2014-02-05T14:49:25Z + +[Term] +id: GO:1902674 +name: right posteriolateral basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of right posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right posteriolateral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right posteriolateral flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right posterolateral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right posterolateral flagellum" EXACT [GOC:TermGenie] +synonym: "right posteriolateral flagellum ciliary basal body" EXACT [] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097557 ! right posteriolateral flagellum +relationship: part_of GO:0097557 ! right posteriolateral flagellum +created_by: pr +creation_date: 2014-02-05T14:52:04Z + +[Term] +id: GO:1902675 +name: left ventral basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of left ventral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left ventral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left ventral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left ventral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left ventral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left ventral flagellum" EXACT [GOC:TermGenie] +synonym: "left ventral flagellum ciliary basal body" EXACT [] +synonym: "microtubule basal body of left ventral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left ventral flagellum" EXACT [GOC:TermGenie] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097558 ! left ventral flagellum +relationship: part_of GO:0097558 ! left ventral flagellum +created_by: pr +creation_date: 2014-02-05T14:54:54Z + +[Term] +id: GO:1902676 +name: right ventral basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of right ventral cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right ventral flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right ventral cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right ventral flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right ventral cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right ventral flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right ventral cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right ventral flagellum" EXACT [GOC:TermGenie] +synonym: "right ventral flagellum ciliary basal body" EXACT [] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097559 ! right ventral flagellum +relationship: part_of GO:0097559 ! right ventral flagellum +created_by: pr +creation_date: 2014-02-05T14:58:13Z + +[Term] +id: GO:1902677 +name: left caudal basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of left caudal cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of left caudal flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left caudal cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of left caudal flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left caudal cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of left caudal flagellum" EXACT [GOC:TermGenie] +synonym: "left caudal flagellum ciliary basal body" EXACT [] +synonym: "microtubule basal body of left caudal cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of left caudal flagellum" EXACT [GOC:TermGenie] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097560 ! left caudal flagellum +relationship: part_of GO:0097560 ! left caudal flagellum +created_by: pr +creation_date: 2014-02-05T15:00:36Z + +[Term] +id: GO:1902678 +name: right caudal basal body +namespace: cellular_component +def: "Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage)." [GO_REF:0000064, GOC:giardia, GOC:TermGenie, ISBN:9780124260207, PMID:16607022, PMID:5961344] +comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior. +synonym: "cilial basal body of right caudal cilium" EXACT [GOC:TermGenie] +synonym: "cilial basal body of right caudal flagellum" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right caudal cilium" EXACT [GOC:TermGenie] +synonym: "ciliary basal body of right caudal flagellum" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right caudal cilium" EXACT [GOC:TermGenie] +synonym: "cilium basal body of right caudal flagellum" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right caudal cilium" EXACT [GOC:TermGenie] +synonym: "microtubule basal body of right caudal flagellum" EXACT [GOC:TermGenie] +synonym: "right caudal flagellum ciliary basal body" EXACT [] +is_a: GO:0036064 ! ciliary basal body +intersection_of: GO:0036064 ! ciliary basal body +intersection_of: part_of GO:0097561 ! right caudal flagellum +relationship: part_of GO:0097561 ! right caudal flagellum +created_by: pr +creation_date: 2014-02-05T15:02:56Z + +[Term] +id: GO:1902679 +name: negative regulation of RNA biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] +synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA formation" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:2001141 ! regulation of RNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032774 ! RNA biosynthetic process +relationship: negatively_regulates GO:0032774 ! RNA biosynthetic process +created_by: jl +creation_date: 2014-02-05T16:32:01Z + +[Term] +id: GO:1902680 +name: positive regulation of RNA biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] +synonym: "activation of RNA anabolism" NARROW [GOC:TermGenie] +synonym: "activation of RNA biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of RNA biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of RNA formation" NARROW [GOC:TermGenie] +synonym: "activation of RNA synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:2001141 ! regulation of RNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032774 ! RNA biosynthetic process +relationship: positively_regulates GO:0032774 ! RNA biosynthetic process +created_by: jl +creation_date: 2014-02-05T16:32:10Z + +[Term] +id: GO:1902681 +name: regulation of replication fork arrest at rDNA repeats +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats." [GO_REF:0000058, GOC:TermGenie, PMID:23260662] +synonym: "regulation of replication fork arrest at ribosomal DNA repeats" EXACT [GOC:TermGenie] +synonym: "regulation of replication fork blocking at rDNA repeats" EXACT [GOC:TermGenie] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031582 ! replication fork arrest at rDNA repeats +relationship: regulates GO:0031582 ! replication fork arrest at rDNA repeats +created_by: mah +creation_date: 2014-02-05T16:59:21Z + +[Term] +id: GO:1902682 +name: protein localization to pericentric heterochromatin +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in the pericentric heterochromatin." [GO_REF:0000087, GOC:TermGenie, PMID:20211136] +synonym: "protein localisation in nuclear centromeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localisation to nuclear centromeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localization in nuclear centromeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localization to nuclear pericentric heterochromatin" RELATED [] +is_a: GO:0034504 ! protein localization to nucleus +is_a: GO:0071459 ! protein localization to chromosome, centromeric region +is_a: GO:0097355 ! protein localization to heterochromatin +created_by: mah +creation_date: 2014-02-05T16:59:30Z + +[Term] +id: GO:1902683 +name: regulation of receptor localization to synapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor localization to synapse." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22252129] +synonym: "regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +is_a: GO:1902473 ! regulation of protein localization to synapse +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097120 ! receptor localization to synapse +relationship: regulates GO:0097120 ! receptor localization to synapse +created_by: kmv +creation_date: 2014-02-07T17:38:31Z + +[Term] +id: GO:1902684 +name: negative regulation of receptor localization to synapse +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22252129] +synonym: "down regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor localization to synapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor localization to synapse" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor localization to synapse" EXACT [GOC:TermGenie] +synonym: "inhibition of receptor localisation to synapse" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor localization to synapse" NARROW [GOC:TermGenie] +synonym: "negative regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1902683 ! regulation of receptor localization to synapse +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097120 ! receptor localization to synapse +relationship: negatively_regulates GO:0097120 ! receptor localization to synapse +created_by: kmv +creation_date: 2014-02-07T17:38:41Z + +[Term] +id: GO:1902685 +name: positive regulation of receptor localization to synapse +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor localization to synapse." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22252129] +synonym: "activation of receptor localisation to synapse" NARROW [GOC:TermGenie] +synonym: "activation of receptor localization to synapse" NARROW [GOC:TermGenie] +synonym: "positive regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor localization to synapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor localization to synapse" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor localisation to synapse" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor localization to synapse" EXACT [GOC:TermGenie] +is_a: GO:1902474 ! positive regulation of protein localization to synapse +is_a: GO:1902683 ! regulation of receptor localization to synapse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097120 ! receptor localization to synapse +relationship: positively_regulates GO:0097120 ! receptor localization to synapse +created_by: kmv +creation_date: 2014-02-07T17:38:51Z + +[Term] +id: GO:1902686 +name: mitochondrial outer membrane permeabilization involved in programmed cell death +namespace: biological_process +def: "The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie, PMID:20151314] +synonym: "mitochondrial membrane permeability transition involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in PCD" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeability transition involved in regulated cell death" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in PCD" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial membrane permeabilization involved in regulated cell death" RELATED [GOC:TermGenie] +synonym: "mitochondrial outer membrane permeabilization during programmed cell death" EXACT [] +synonym: "mitochondrial permeability transition involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in PCD" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in programmed cell death" NARROW [GOC:TermGenie] +synonym: "mitochondrial permeability transition involved in regulated cell death" RELATED [GOC:TermGenie] +synonym: "MPT involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "MPT involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "MPT involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "MPT involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "MPT involved in PCD" NARROW [GOC:TermGenie] +synonym: "MPT involved in programmed cell death" NARROW [GOC:TermGenie] +synonym: "MPT involved in regulated cell death" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in PCD" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitochondrial membrane permeability involved in programmed cell death" EXACT [] +synonym: "positive regulation of mitochondrial membrane permeability involved in regulated cell death" RELATED [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in caspase-independent apoptosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in caspase-independent cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in non-apoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in nonapoptotic programmed cell death" NARROW [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in PCD" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in programmed cell death" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport across mitochondrial membrane involved in regulated cell death" RELATED [GOC:TermGenie] +is_a: GO:0035794 ! positive regulation of mitochondrial membrane permeability +intersection_of: GO:0035794 ! positive regulation of mitochondrial membrane permeability +intersection_of: part_of GO:0012501 ! programmed cell death +relationship: part_of GO:0012501 ! programmed cell death +created_by: pr +creation_date: 2014-02-10T12:56:34Z + +[Term] +id: GO:1902687 +name: glucosidase complex +namespace: cellular_component +def: "A protein complex which is capable of glucosidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:23826932] +comment: An example of this is ygjK in E. coli (P42592) in PMID:23826932. +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2014-02-12T10:55:10Z + +[Term] +id: GO:1902688 +name: regulation of NAD metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of NAD metabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:19846558] +synonym: "regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019674 ! NAD metabolic process +relationship: regulates GO:0019674 ! NAD metabolic process +created_by: di +creation_date: 2014-02-12T18:58:50Z + +[Term] +id: GO:1902689 +name: negative regulation of NAD metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:19846558] +synonym: "down regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "down regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "down-regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "downregulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of NAD (oxidized) metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of NAD (oxidized) metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of NAD metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of NAD metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of nicotinamide adenine dinucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of nicotinamide adenine dinucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidized NAD metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidized NAD metabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidized nicotinamide adenine dinucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidized nicotinamide adenine dinucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:1902688 ! regulation of NAD metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019674 ! NAD metabolic process +relationship: negatively_regulates GO:0019674 ! NAD metabolic process +created_by: di +creation_date: 2014-02-12T18:58:59Z + +[Term] +id: GO:1902690 +name: positive regulation of NAD metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NAD metabolic process." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:19846558] +synonym: "activation of NAD (oxidized) metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of NAD (oxidized) metabolism" NARROW [GOC:TermGenie] +synonym: "activation of NAD metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of NAD metabolism" NARROW [GOC:TermGenie] +synonym: "activation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of nicotinamide adenine dinucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of nicotinamide adenine dinucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "activation of oxidized NAD metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of oxidized NAD metabolism" NARROW [GOC:TermGenie] +synonym: "activation of oxidized nicotinamide adenine dinucleotide metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of oxidized nicotinamide adenine dinucleotide metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "up regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "up-regulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD (oxidized) metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD (oxidized) metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of NAD phosphorylation and dephosphorylation" NARROW [GOC:TermGenie] +synonym: "upregulation of nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidized NAD metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidized NAD metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidized nicotinamide adenine dinucleotide metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidized nicotinamide adenine dinucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:1902688 ! regulation of NAD metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019674 ! NAD metabolic process +relationship: positively_regulates GO:0019674 ! NAD metabolic process +created_by: di +creation_date: 2014-02-12T18:59:09Z + +[Term] +id: GO:1902691 +name: respiratory basal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell." [GO_REF:0000086, GOC:TermGenie, MP:0011114, PMID:17909629] +comment: Changes in the lineage choice of ABCs or their undifferentiated daughters might contribute to the mucous cell hyperplasia, metaplasia or squamous metaplasia seen in many respiratory disorders +synonym: "airway basal cell differentiation" EXACT [MP:0011114] +is_a: GO:0030855 ! epithelial cell differentiation +is_a: GO:0048863 ! stem cell differentiation +created_by: cjm +creation_date: 2014-02-13T23:41:24Z + +[Term] +id: GO:1902692 +name: regulation of neuroblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496] +is_a: GO:0050767 ! regulation of neurogenesis +is_a: GO:0072091 ! regulation of stem cell proliferation +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007405 ! neuroblast proliferation +relationship: regulates GO:0007405 ! neuroblast proliferation +created_by: rl +creation_date: 2014-02-18T10:03:31Z + +[Term] +id: GO:1902693 +name: superoxide dismutase complex +namespace: cellular_component +def: "A protein complex which is capable of superoxide dismutase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:10026301] +comment: An example of this is SOD1 in Saccharomyces cerevisiae S288c (UniProt symbol P00445) in PMID:10026301. +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2014-02-18T11:10:11Z + +[Term] +id: GO:1902694 +name: superoxide dismutase copper chaperone complex +namespace: cellular_component +def: "A protein complex which is capable of superoxide dismutase copper chaperone activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:10426947] +comment: An example of this is CCS1 in Saccharomyces cerevisiae S288c (UniProt symbol P40202) in PMID:10426947. +is_a: GO:0150005 ! enzyme activator complex +is_a: GO:1902695 ! metallochaperone complex +created_by: bhm +creation_date: 2014-02-18T11:13:45Z + +[Term] +id: GO:1902695 +name: metallochaperone complex +namespace: cellular_component +def: "A protein complex which is capable of metallochaperone activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:10426947] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-02-18T11:34:40Z + +[Term] +id: GO:1902696 +name: glycine catabolic process to isobutanol +namespace: biological_process +alt_id: GO:1990293 +def: "The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:23642236] +synonym: "glycine breakdown to isobutanol" EXACT [GOC:TermGenie] +synonym: "glycine catabolism to isobutanol" EXACT [GOC:TermGenie] +synonym: "glycine degradation to isobutanol" EXACT [GOC:TermGenie] +is_a: GO:0006546 ! glycine catabolic process +is_a: GO:1901960 ! isobutanol metabolic process +created_by: tb +creation_date: 2014-02-19T18:00:12Z + +[Term] +id: GO:1902697 +name: valine catabolic process to isobutanol +namespace: biological_process +alt_id: GO:1990292 +def: "The chemical reactions and pathways resulting in the breakdown of valine to isobutanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:9748245] +synonym: "valine breakdown to isobutanol" EXACT [GOC:TermGenie] +synonym: "valine catabolism to isobutanol" EXACT [GOC:TermGenie] +synonym: "valine degradation to isobutanol" EXACT [GOC:TermGenie] +is_a: GO:0006574 ! valine catabolic process +is_a: GO:1901960 ! isobutanol metabolic process +created_by: tb +creation_date: 2014-02-19T18:28:19Z + +[Term] +id: GO:1902698 +name: pentose catabolic process to butyrate +namespace: biological_process +alt_id: GO:1990288 +def: "The chemical reactions and pathways resulting in the breakdown of pentose to butyrate." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "acidogenesis" BROAD [GOC:tt] +synonym: "pentose breakdown to butyrate" EXACT [GOC:TermGenie] +synonym: "pentose catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "pentose degradation to butyrate" EXACT [GOC:TermGenie] +is_a: GO:0019323 ! pentose catabolic process +is_a: GO:0019605 ! butyrate metabolic process +created_by: tb +creation_date: 2014-02-19T18:28:28Z + +[Term] +id: GO:1902699 +name: pentose catabolic process to acetate +namespace: biological_process +alt_id: GO:1990289 +def: "The chemical reactions and pathways resulting in the breakdown of pentose to acetate." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "acidogenesis" BROAD [GOC:tt] +synonym: "pentose breakdown to acetate" EXACT [GOC:TermGenie] +synonym: "pentose catabolism to acetate" EXACT [GOC:TermGenie] +synonym: "pentose degradation to acetate" EXACT [GOC:TermGenie] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0019323 ! pentose catabolic process +created_by: tb +creation_date: 2014-02-19T18:28:38Z + +[Term] +id: GO:1902700 +name: pentose catabolic process to butan-1-ol +namespace: biological_process +alt_id: GO:1990290 +def: "The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "pentose breakdown to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "pentose catabolic process to 1-butanol" EXACT [GOC:tt] +synonym: "pentose catabolic process to butanol" EXACT [GOC:tt] +synonym: "pentose catabolism to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "pentose degradation to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "solventogenesis" BROAD [GOC:tt] +is_a: GO:0019323 ! pentose catabolic process +is_a: GO:0071270 ! 1-butanol metabolic process +created_by: tb +creation_date: 2014-02-19T18:28:47Z + +[Term] +id: GO:1902701 +name: pentose catabolic process to propan-2-ol +namespace: biological_process +alt_id: GO:1990291 +def: "The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "pentose breakdown to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "pentose catabolic process to isopropanol" EXACT [GOC:tt] +synonym: "pentose catabolic process to isopropyl alcohol" EXACT [GOC:tt] +synonym: "pentose catabolism to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "pentose degradation to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "solventogenesis" BROAD [GOC:tt] +is_a: GO:0019323 ! pentose catabolic process +is_a: GO:1902639 ! propan-2-ol metabolic process +created_by: tb +creation_date: 2014-02-19T18:28:57Z + +[Term] +id: GO:1902702 +name: hexose catabolic process to propan-2-ol +namespace: biological_process +alt_id: GO:1990283 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "hexose breakdown to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "hexose catabolic process to isopropanol" EXACT [GOC:tt] +synonym: "hexose catabolic process to isopropyl alcohol" EXACT [GOC:tt] +synonym: "hexose catabolism to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "hexose degradation to propan-2-ol" EXACT [GOC:TermGenie] +synonym: "solventogenesis" RELATED [GOC:tt] +is_a: GO:0019320 ! hexose catabolic process +is_a: GO:1902639 ! propan-2-ol metabolic process +created_by: tb +creation_date: 2014-02-19T18:42:54Z + +[Term] +id: GO:1902703 +name: hexose catabolic process to butan-1-ol +namespace: biological_process +alt_id: GO:1990284 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "hexose breakdown to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "hexose catabolic process to 1-butanol" EXACT [GOC:tt] +synonym: "hexose catabolic process to butanol" EXACT [GOC:tt] +synonym: "hexose catabolism to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "hexose degradation to butan-1-ol" EXACT [GOC:TermGenie] +synonym: "solventogenesis" BROAD [GOC:tt] +is_a: GO:0019320 ! hexose catabolic process +is_a: GO:0071270 ! 1-butanol metabolic process +created_by: tb +creation_date: 2014-02-19T18:43:04Z + +[Term] +id: GO:1902704 +name: hexose catabolic process to acetone +namespace: biological_process +alt_id: GO:1990285 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to acetone." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "hexose breakdown to acetone" EXACT [GOC:TermGenie] +synonym: "hexose catabolic process to 2-propanone" EXACT [GOC:tt] +synonym: "hexose catabolism to acetone" EXACT [GOC:TermGenie] +synonym: "hexose degradation to acetone" EXACT [GOC:TermGenie] +synonym: "solventogenesis" BROAD [GOC:tt] +is_a: GO:0019320 ! hexose catabolic process +is_a: GO:0043443 ! acetone metabolic process +created_by: tb +creation_date: 2014-02-19T18:43:13Z + +[Term] +id: GO:1902705 +name: hexose catabolic process to butyrate +namespace: biological_process +alt_id: GO:1990287 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to butyrate." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "acidogenesis" BROAD [GOC:tt] +synonym: "hexose breakdown to butyrate" EXACT [GOC:TermGenie] +synonym: "hexose catabolism to butyrate" EXACT [GOC:TermGenie] +synonym: "hexose degradation to butyrate" EXACT [GOC:TermGenie] +is_a: GO:0019320 ! hexose catabolic process +is_a: GO:0019605 ! butyrate metabolic process +created_by: tb +creation_date: 2014-02-19T18:43:32Z + +[Term] +id: GO:1902706 +name: hexose catabolic process to acetate +namespace: biological_process +alt_id: GO:1990286 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to acetate." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "acidogenesis" BROAD [GOC:tt] +synonym: "hexose breakdown to acetate" EXACT [GOC:TermGenie] +synonym: "hexose catabolism to acetate" EXACT [GOC:TermGenie] +synonym: "hexose degradation to acetate" EXACT [GOC:TermGenie] +is_a: GO:0006083 ! acetate metabolic process +is_a: GO:0019320 ! hexose catabolic process +created_by: tb +creation_date: 2014-02-19T18:43:23Z + +[Term] +id: GO:1902707 +name: hexose catabolic process to ethanol +namespace: biological_process +alt_id: GO:1990282 +def: "The chemical reactions and pathways resulting in the breakdown of hexose to ethanol." [GO_REF:0000093, GOC:mengo_curators, GOC:TermGenie, PMID:18727018, PMID:19539744] +synonym: "hexose breakdown to ethanol" EXACT [GOC:TermGenie] +synonym: "hexose catabolism to ethanol" EXACT [GOC:TermGenie] +synonym: "hexose degradation to ethanol" EXACT [GOC:TermGenie] +synonym: "solventogenesis" BROAD [GOC:tt] +is_a: GO:0006067 ! ethanol metabolic process +is_a: GO:0019320 ! hexose catabolic process +created_by: tb +creation_date: 2014-02-19T21:33:08Z + +[Term] +id: GO:1902708 +name: response to plumbagin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23028742] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061476 ! response to anticoagulant +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: mah +creation_date: 2014-02-20T13:49:54Z + +[Term] +id: GO:1902709 +name: cellular response to plumbagin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23028742] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1902708 ! response to plumbagin +created_by: mah +creation_date: 2014-02-20T13:50:04Z + +[Term] +id: GO:1902710 +name: GABA receptor complex +namespace: cellular_component +def: "A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18790874] +synonym: "gamma-aminobutyric acid receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +created_by: bhm +creation_date: 2014-02-20T16:07:48Z + +[Term] +id: GO:1902711 +name: GABA-A receptor complex +namespace: cellular_component +def: "A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor)." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18790874] +comment: An example of this is GBRA1 in human (UniProt symbol P14867) in PMID:18790874. +is_a: GO:1902710 ! GABA receptor complex +created_by: bhm +creation_date: 2014-02-21T09:19:58Z + +[Term] +id: GO:1902712 +name: G protein-coupled GABA receptor complex +namespace: cellular_component +def: "A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18790874] +comment: An example of this is GABR1 in human (UniProt symbol Q9UBS5) in PMID:18790874. +synonym: "G-protein coupled GABA receptor complex" EXACT [] +is_a: GO:0038037 ! G protein-coupled receptor dimeric complex +is_a: GO:0098878 ! neurotransmitter receptor complex +is_a: GO:1902710 ! GABA receptor complex +created_by: bhm +creation_date: 2014-02-21T09:47:03Z + +[Term] +id: GO:1902713 +name: regulation of interferon-gamma secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interferon-gamma secretion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:19109405] +synonym: "regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "regulation of type II IFN secretion" BROAD [GOC:TermGenie] +synonym: "regulation of type II interferon secretion" BROAD [GOC:TermGenie] +is_a: GO:0032649 ! regulation of interferon-gamma production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072643 ! interferon-gamma secretion +relationship: regulates GO:0072643 ! interferon-gamma secretion +created_by: als +creation_date: 2014-02-21T16:34:19Z + +[Term] +id: GO:1902714 +name: negative regulation of interferon-gamma secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interferon-gamma secretion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:19109405] +synonym: "down regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of IFN-gamma secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of IFNG secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of interferon-gamma secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of IFNG secretion" EXACT [GOC:TermGenie] +is_a: GO:0032689 ! negative regulation of interferon-gamma production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1902713 ! regulation of interferon-gamma secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072643 ! interferon-gamma secretion +relationship: negatively_regulates GO:0072643 ! interferon-gamma secretion +created_by: als +creation_date: 2014-02-21T16:34:29Z + +[Term] +id: GO:1902715 +name: positive regulation of interferon-gamma secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:19109405] +synonym: "activation of IFN-gamma secretion" NARROW [GOC:TermGenie] +synonym: "activation of IFNG secretion" NARROW [GOC:TermGenie] +synonym: "activation of interferon-gamma secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IFN-gamma secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IFNG secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of interferon-gamma secretion" EXACT [GOC:TermGenie] +is_a: GO:0032729 ! positive regulation of interferon-gamma production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1902713 ! regulation of interferon-gamma secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072643 ! interferon-gamma secretion +relationship: positively_regulates GO:0072643 ! interferon-gamma secretion +created_by: als +creation_date: 2014-02-21T16:34:38Z + +[Term] +id: GO:1902716 +name: cell cortex of growing cell tip +namespace: cellular_component +def: "Any cell cortex that is part of a growing cell tip." [GO_REF:0000064, GOC:TermGenie, PMID:24146635] +synonym: "cell cortex of growing cell end" EXACT [] +is_a: GO:0051285 ! cell cortex of cell tip +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0035838 ! growing cell tip +relationship: part_of GO:0035838 ! growing cell tip +created_by: mah +creation_date: 2014-02-24T15:46:57Z + +[Term] +id: GO:1902717 +name: obsolete sequestering of iron ion +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of iron ion." [GO_REF:0000058, GOC:TermGenie, PMID:3099306] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "sequestering of iron ion" EXACT [] +is_obsolete: true +created_by: mr +creation_date: 2014-02-24T16:08:43Z + +[Term] +id: GO:1902718 +name: obsolete sequestering of copper ion +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of copper ion." [GO_REF:0000058, GOC:TermGenie, PMID:3099306] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "sequestering of copper ion" EXACT [] +is_obsolete: true +created_by: mr +creation_date: 2014-02-24T16:08:53Z + +[Term] +id: GO:1902719 +name: obsolete extracellular sequestering of copper ion +namespace: biological_process +def: "OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system." [GO_REF:0000058, GOC:TermGenie, PMID:3099306] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "extracellular sequestering of copper ion" EXACT [] +is_obsolete: true +created_by: mr +creation_date: 2014-02-24T16:09:09Z + +[Term] +id: GO:1902720 +name: obsolete intracellular sequestering of copper ion +namespace: biological_process +def: "OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system." [GO_REF:0000058, GOC:TermGenie, PMID:3099306] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "intracellular sequestering of copper ion" EXACT [] +is_obsolete: true +created_by: mr +creation_date: 2014-02-24T16:09:18Z + +[Term] +id: GO:1902721 +name: negative regulation of prolactin secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:16159377] +synonym: "down regulation of prolactin secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of prolactin secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of prolactin secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of prolactin secretion" NARROW [GOC:TermGenie] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070459 ! prolactin secretion +relationship: negatively_regulates GO:0070459 ! prolactin secretion +created_by: mr +creation_date: 2014-02-24T16:09:28Z + +[Term] +id: GO:1902722 +name: positive regulation of prolactin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of prolactin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:16159377] +synonym: "activation of prolactin secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of prolactin secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of prolactin secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of prolactin secretion" EXACT [GOC:TermGenie] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070459 ! prolactin secretion +relationship: positively_regulates GO:0070459 ! prolactin secretion +created_by: mr +creation_date: 2014-02-24T16:09:37Z + +[Term] +id: GO:1902723 +name: negative regulation of skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "down regulation of satellite cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of satellite cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of satellite cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of satellite cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0014842 ! regulation of skeletal muscle satellite cell proliferation +is_a: GO:0014859 ! negative regulation of skeletal muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014841 ! skeletal muscle satellite cell proliferation +relationship: negatively_regulates GO:0014841 ! skeletal muscle satellite cell proliferation +created_by: mr +creation_date: 2014-02-24T16:09:46Z + +[Term] +id: GO:1902724 +name: positive regulation of skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "activation of satellite cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of satellite cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of satellite cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of satellite cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0014842 ! regulation of skeletal muscle satellite cell proliferation +is_a: GO:0014858 ! positive regulation of skeletal muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014841 ! skeletal muscle satellite cell proliferation +relationship: positively_regulates GO:0014841 ! skeletal muscle satellite cell proliferation +created_by: mr +creation_date: 2014-02-24T16:09:56Z + +[Term] +id: GO:1902725 +name: negative regulation of satellite cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "down regulation of satellite cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of satellite cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of satellite cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of satellite cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014816 ! skeletal muscle satellite cell differentiation +relationship: negatively_regulates GO:0014816 ! skeletal muscle satellite cell differentiation +created_by: mr +creation_date: 2014-02-24T16:10:05Z + +[Term] +id: GO:1902726 +name: positive regulation of skeletal muscle satellite cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of satellite cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "activation of satellite cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of satellite cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of satellite cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of satellite cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014816 ! skeletal muscle satellite cell differentiation +relationship: positively_regulates GO:0014816 ! skeletal muscle satellite cell differentiation +created_by: mr +creation_date: 2014-02-24T16:10:14Z + +[Term] +id: GO:1902727 +name: negative regulation of growth factor dependent skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +is_a: GO:1902723 ! negative regulation of skeletal muscle satellite cell proliferation +created_by: mr +creation_date: 2014-02-24T16:10:24Z + +[Term] +id: GO:1902728 +name: positive regulation of growth factor dependent skeletal muscle satellite cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +is_a: GO:1902724 ! positive regulation of skeletal muscle satellite cell proliferation +created_by: mr +creation_date: 2014-02-24T16:10:33Z + +[Term] +id: GO:1902729 +name: negative regulation of proteoglycan biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "down regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "down regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "downregulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of proteoglycan anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of proteoglycan biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of proteoglycan biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of proteoglycan formation" NARROW [GOC:TermGenie] +synonym: "inhibition of proteoglycan synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030166 ! proteoglycan biosynthetic process +relationship: negatively_regulates GO:0030166 ! proteoglycan biosynthetic process +created_by: mr +creation_date: 2014-02-24T16:10:43Z + +[Term] +id: GO:1902730 +name: positive regulation of proteoglycan biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "activation of proteoglycan anabolism" NARROW [GOC:TermGenie] +synonym: "activation of proteoglycan biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of proteoglycan biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of proteoglycan formation" NARROW [GOC:TermGenie] +synonym: "activation of proteoglycan synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "up regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of proteoglycan anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of proteoglycan biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of proteoglycan biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of proteoglycan formation" EXACT [GOC:TermGenie] +synonym: "upregulation of proteoglycan synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030166 ! proteoglycan biosynthetic process +relationship: positively_regulates GO:0030166 ! proteoglycan biosynthetic process +created_by: mr +creation_date: 2014-02-24T16:10:52Z + +[Term] +id: GO:1902731 +name: negative regulation of chondrocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "down regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of cartilage cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of chondrocyte cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of chondrocyte proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "negative regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035988 ! chondrocyte proliferation +relationship: negatively_regulates GO:0035988 ! chondrocyte proliferation +created_by: mr +creation_date: 2014-02-24T16:11:02Z + +[Term] +id: GO:1902732 +name: positive regulation of chondrocyte proliferation +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +synonym: "activation of cartilage cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of chondrocyte cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of chondrocyte proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "positive regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of cartilage cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of chondrocyte cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of chondrocyte proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035988 ! chondrocyte proliferation +relationship: positively_regulates GO:0035988 ! chondrocyte proliferation +created_by: mr +creation_date: 2014-02-24T16:11:18Z + +[Term] +id: GO:1902733 +name: regulation of growth plate cartilage chondrocyte differentiation +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:23212449] +is_a: GO:0046620 ! regulation of organ growth +is_a: GO:1902738 ! regulation of chondrocyte differentiation involved in endochondral bone morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003418 ! growth plate cartilage chondrocyte differentiation +relationship: regulates GO:0003418 ! growth plate cartilage chondrocyte differentiation +created_by: mr +creation_date: 2014-02-24T16:11:28Z + +[Term] +id: GO:1902734 +name: regulation of receptor-mediated virion attachment to host cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18385238] +synonym: "regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046813 ! receptor-mediated virion attachment to host cell +relationship: regulates GO:0046813 ! receptor-mediated virion attachment to host cell +created_by: als +creation_date: 2014-02-25T12:25:56Z + +[Term] +id: GO:1902735 +name: negative regulation of receptor-mediated virion attachment to host cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18385238] +synonym: "down regulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "down regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "downregulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "inhibition of receptor-mediated virion attachment to host cell" NARROW [GOC:TermGenie] +synonym: "inhibition of virion attachment, binding of host cell surface receptor" NARROW [GOC:TermGenie] +synonym: "negative regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +is_a: GO:1902734 ! regulation of receptor-mediated virion attachment to host cell +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046813 ! receptor-mediated virion attachment to host cell +relationship: negatively_regulates GO:0046813 ! receptor-mediated virion attachment to host cell +created_by: als +creation_date: 2014-02-25T12:26:06Z + +[Term] +id: GO:1902736 +name: positive regulation of receptor-mediated virion attachment to host cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18385238] +synonym: "activation of receptor-mediated virion attachment to host cell" NARROW [GOC:TermGenie] +synonym: "activation of virion attachment, binding of host cell surface receptor" NARROW [GOC:TermGenie] +synonym: "positive regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "up regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor-mediated virion attachment to host cell" EXACT [GOC:TermGenie] +synonym: "upregulation of virion attachment, binding of host cell surface receptor" EXACT [GOC:TermGenie] +is_a: GO:1902734 ! regulation of receptor-mediated virion attachment to host cell +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046813 ! receptor-mediated virion attachment to host cell +relationship: positively_regulates GO:0046813 ! receptor-mediated virion attachment to host cell +created_by: als +creation_date: 2014-02-25T12:26:16Z + +[Term] +id: GO:1902737 +name: dendritic filopodium +namespace: cellular_component +def: "A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines." [GO_REF:0000064, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24464040, Wikipedia:Dendritic_filopodia] +comment: Dendritic filopodia are generally less-well studied than dendritic spines because their transient nature makes them difficult to detect with traditional microscopy techniques, and because they are sometimes destroyed by sample preparation. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473. +synonym: "dendrite filopodium" EXACT [] +is_a: GO:0030175 ! filopodium +is_a: GO:0043005 ! neuron projection +intersection_of: GO:0030175 ! filopodium +intersection_of: part_of GO:0030425 ! dendrite +relationship: part_of GO:0030425 ! dendrite +created_by: pr +creation_date: 2014-02-26T14:28:26Z + +[Term] +id: GO:1902738 +name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546] +is_a: GO:0032330 ! regulation of chondrocyte differentiation +is_a: GO:1903010 ! regulation of bone development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis +relationship: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis +created_by: mr +creation_date: 2014-02-26T15:36:15Z + +[Term] +id: GO:1902739 +name: regulation of interferon-alpha secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interferon-alpha secretion." [GO_REF:0000058, GOC:TermGenie, PMID:19262501] +synonym: "regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "regulation of IFNA secretion" EXACT [GOC:TermGenie] +is_a: GO:0032647 ! regulation of interferon-alpha production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072642 ! interferon-alpha secretion +relationship: regulates GO:0072642 ! interferon-alpha secretion +created_by: mr +creation_date: 2014-02-26T22:13:20Z + +[Term] +id: GO:1902740 +name: negative regulation of interferon-alpha secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interferon-alpha secretion." [GO_REF:0000058, GOC:TermGenie, PMID:19262501] +synonym: "down regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of IFN-alpha secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of IFNA secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of interferon-alpha secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of IFNA secretion" EXACT [GOC:TermGenie] +is_a: GO:0032687 ! negative regulation of interferon-alpha production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1902739 ! regulation of interferon-alpha secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072642 ! interferon-alpha secretion +relationship: negatively_regulates GO:0072642 ! interferon-alpha secretion +created_by: mr +creation_date: 2014-02-26T22:13:30Z + +[Term] +id: GO:1902741 +name: positive regulation of interferon-alpha secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interferon-alpha secretion." [GO_REF:0000058, GOC:TermGenie, PMID:19262501] +synonym: "activation of IFN-alpha secretion" NARROW [GOC:TermGenie] +synonym: "activation of IFNA secretion" NARROW [GOC:TermGenie] +synonym: "activation of interferon-alpha secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IFN-alpha secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IFNA secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of interferon-alpha secretion" EXACT [GOC:TermGenie] +is_a: GO:0032727 ! positive regulation of interferon-alpha production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1902739 ! regulation of interferon-alpha secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072642 ! interferon-alpha secretion +relationship: positively_regulates GO:0072642 ! interferon-alpha secretion +created_by: mr +creation_date: 2014-02-26T22:13:40Z + +[Term] +id: GO:1902742 +name: apoptotic process involved in development +namespace: biological_process +def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie] +synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "apoptotic process involved in anatomical structure development" EXACT [] +synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +intersection_of: GO:0006915 ! apoptotic process +intersection_of: part_of GO:0048856 ! anatomical structure development +relationship: part_of GO:0048856 ! anatomical structure development +created_by: pr +creation_date: 2014-02-28T13:09:43Z + +[Term] +id: GO:1902743 +name: regulation of lamellipodium organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lamellipodium organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:16054028] +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097581 ! lamellipodium organization +relationship: regulates GO:0097581 ! lamellipodium organization +created_by: als +creation_date: 2014-02-28T16:27:30Z + +[Term] +id: GO:1902744 +name: negative regulation of lamellipodium organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:16054028] +synonym: "down regulation of lamellipodium organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of lamellipodium organization" EXACT [GOC:TermGenie] +synonym: "downregulation of lamellipodium organization" EXACT [GOC:TermGenie] +synonym: "inhibition of lamellipodium organization" NARROW [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:1902743 ! regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097581 ! lamellipodium organization +relationship: negatively_regulates GO:0097581 ! lamellipodium organization +created_by: als +creation_date: 2014-02-28T16:27:39Z + +[Term] +id: GO:1902745 +name: positive regulation of lamellipodium organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lamellipodium organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:16054028] +synonym: "activation of lamellipodium organization" NARROW [GOC:TermGenie] +synonym: "up regulation of lamellipodium organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of lamellipodium organization" EXACT [GOC:TermGenie] +synonym: "upregulation of lamellipodium organization" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:1902743 ! regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097581 ! lamellipodium organization +relationship: positively_regulates GO:0097581 ! lamellipodium organization +created_by: als +creation_date: 2014-02-28T16:27:49Z + +[Term] +id: GO:1902746 +name: regulation of lens fiber cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lens fiber cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17592637] +synonym: "regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070306 ! lens fiber cell differentiation +relationship: regulates GO:0070306 ! lens fiber cell differentiation +created_by: mr +creation_date: 2014-03-03T23:18:50Z + +[Term] +id: GO:1902747 +name: negative regulation of lens fiber cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17592637] +synonym: "down regulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of lens fiber cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of lens fibre cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902746 ! regulation of lens fiber cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070306 ! lens fiber cell differentiation +relationship: negatively_regulates GO:0070306 ! lens fiber cell differentiation +created_by: mr +creation_date: 2014-03-03T23:19:32Z + +[Term] +id: GO:1902748 +name: positive regulation of lens fiber cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17592637] +synonym: "activation of lens fiber cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of lens fibre cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of lens fiber cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of lens fibre cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902746 ! regulation of lens fiber cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070306 ! lens fiber cell differentiation +relationship: positively_regulates GO:0070306 ! lens fiber cell differentiation +created_by: mr +creation_date: 2014-03-03T23:20:12Z + +[Term] +id: GO:1902749 +name: regulation of cell cycle G2/M phase transition +namespace: biological_process +def: "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." [GO_REF:0000058, GOC:jl, GOC:TermGenie] +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044839 ! cell cycle G2/M phase transition +relationship: regulates GO:0044839 ! cell cycle G2/M phase transition +created_by: jl +creation_date: 2014-03-05T15:38:15Z + +[Term] +id: GO:1902750 +name: negative regulation of cell cycle G2/M phase transition +namespace: biological_process +def: "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." [GO_REF:0000058, GOC:jl, GOC:TermGenie] +synonym: "down regulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +synonym: "inhibition of cell cycle G2/M phase transition" NARROW [GOC:TermGenie] +is_a: GO:1901988 ! negative regulation of cell cycle phase transition +is_a: GO:1902749 ! regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044839 ! cell cycle G2/M phase transition +relationship: negatively_regulates GO:0044839 ! cell cycle G2/M phase transition +created_by: jl +creation_date: 2014-03-05T15:38:21Z + +[Term] +id: GO:1902751 +name: positive regulation of cell cycle G2/M phase transition +namespace: biological_process +def: "Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." [GO_REF:0000058, GOC:jl, GOC:TermGenie] +synonym: "activation of cell cycle G2/M phase transition" NARROW [GOC:TermGenie] +synonym: "up regulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle G2/M phase transition" EXACT [GOC:TermGenie] +is_a: GO:1901989 ! positive regulation of cell cycle phase transition +is_a: GO:1902749 ! regulation of cell cycle G2/M phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044839 ! cell cycle G2/M phase transition +relationship: positively_regulates GO:0044839 ! cell cycle G2/M phase transition +created_by: jl +creation_date: 2014-03-05T15:38:27Z + +[Term] +id: GO:1902752 +name: regulation of renal amino acid absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of renal amino acid absorption." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:1526373] +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990297 ! renal amino acid absorption +relationship: regulates GO:1990297 ! renal amino acid absorption +created_by: hjd +creation_date: 2014-03-05T15:43:55Z + +[Term] +id: GO:1902753 +name: negative regulation of renal amino acid absorption +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:1526373] +synonym: "down regulation of renal amino acid absorption" EXACT [GOC:TermGenie] +synonym: "down-regulation of renal amino acid absorption" EXACT [GOC:TermGenie] +synonym: "downregulation of renal amino acid absorption" EXACT [GOC:TermGenie] +synonym: "inhibition of renal amino acid absorption" NARROW [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902752 ! regulation of renal amino acid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990297 ! renal amino acid absorption +relationship: negatively_regulates GO:1990297 ! renal amino acid absorption +created_by: hjd +creation_date: 2014-03-05T15:44:01Z + +[Term] +id: GO:1902754 +name: positive regulation of renal amino acid absorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of renal amino acid absorption." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:1526373] +synonym: "activation of renal amino acid absorption" NARROW [GOC:TermGenie] +synonym: "up regulation of renal amino acid absorption" EXACT [GOC:TermGenie] +synonym: "up-regulation of renal amino acid absorption" EXACT [GOC:TermGenie] +synonym: "upregulation of renal amino acid absorption" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902752 ! regulation of renal amino acid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990297 ! renal amino acid absorption +relationship: positively_regulates GO:1990297 ! renal amino acid absorption +created_by: hjd +creation_date: 2014-03-05T15:44:07Z + +[Term] +id: GO:1902755 +name: sulfurated eukaryotic molybdenum cofactor(2-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-)." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:18258600] +synonym: "sulfurated eukaryotic molybdenum cofactor(2-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019720 ! Mo-molybdopterin cofactor metabolic process +created_by: dph +creation_date: 2014-03-05T23:29:13Z + +[Term] +id: GO:1902756 +name: sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-)." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:18258600] +synonym: "sulfurated eukaryotic molybdenum cofactor(2-) anabolism" EXACT [GOC:TermGenie] +synonym: "sulfurated eukaryotic molybdenum cofactor(2-) biosynthesis" EXACT [GOC:TermGenie] +synonym: "sulfurated eukaryotic molybdenum cofactor(2-) formation" EXACT [GOC:TermGenie] +synonym: "sulfurated eukaryotic molybdenum cofactor(2-) synthesis" EXACT [GOC:TermGenie] +xref: MetaCyc:PWY-6476 +xref: Reactome:R-HSA-947581 +is_a: GO:0006777 ! Mo-molybdopterin cofactor biosynthetic process +is_a: GO:1902755 ! sulfurated eukaryotic molybdenum cofactor(2-) metabolic process +relationship: has_part GO:0008265 ! Mo-molybdopterin cofactor sulfurase activity +created_by: dph +creation_date: 2014-03-05T23:29:20Z + +[Term] +id: GO:1902757 +name: bis(molybdopterin guanine dinucleotide)molybdenum metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:23201473] +synonym: "bis(molybdopterin guanine dinucleotide)molybdenum metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0019720 ! Mo-molybdopterin cofactor metabolic process +created_by: dph +creation_date: 2014-03-06T13:58:10Z + +[Term] +id: GO:1902758 +name: bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process +namespace: biological_process +alt_id: GO:0061600 +def: "The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:23201473] +synonym: "bis(molybdopterin guanine dinucleotide)molybdenum anabolism" EXACT [GOC:TermGenie] +synonym: "bis(molybdopterin guanine dinucleotide)molybdenum biosynthesis" EXACT [GOC:TermGenie] +synonym: "bis(molybdopterin guanine dinucleotide)molybdenum formation" EXACT [GOC:TermGenie] +synonym: "bis(molybdopterin guanine dinucleotide)molybdenum synthesis" EXACT [GOC:TermGenie] +synonym: "bis-Mo-molybdopterin-guanine dinucleotide cofactor biosynthetic process" EXACT [] +xref: MetaCyc:PWY-5964 +is_a: GO:0006777 ! Mo-molybdopterin cofactor biosynthetic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:1902757 ! bis(molybdopterin guanine dinucleotide)molybdenum metabolic process +relationship: has_part GO:0061603 ! molybdenum cofactor guanylyltransferase activity +created_by: dph +creation_date: 2014-03-06T13:58:18Z + +[Term] +id: GO:1902759 +name: Mo(VI)-molybdopterin cytosine dinucleotide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:23201473] +synonym: "Mo(VI)-molybdopterin cytosine dinucleotide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009117 ! nucleotide metabolic process +is_a: GO:0019720 ! Mo-molybdopterin cofactor metabolic process +created_by: dph +creation_date: 2014-03-06T14:00:31Z + +[Term] +id: GO:1902760 +name: Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process +namespace: biological_process +alt_id: GO:0061601 +def: "The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:23201473] +synonym: "Mo(VI)-molybdopterin cytosine dinucleotide anabolism" EXACT [GOC:TermGenie] +synonym: "Mo(VI)-molybdopterin cytosine dinucleotide biosynthesis" EXACT [GOC:TermGenie] +synonym: "Mo(VI)-molybdopterin cytosine dinucleotide formation" EXACT [GOC:TermGenie] +synonym: "Mo(VI)-molybdopterin cytosine dinucleotide synthesis" EXACT [GOC:TermGenie] +synonym: "Mo-molybdopterin-cytosine-dinucleotide cofactor biosynthetic process" EXACT [] +xref: MetaCyc:PWY-6476 +is_a: GO:0006777 ! Mo-molybdopterin cofactor biosynthetic process +is_a: GO:0009165 ! nucleotide biosynthetic process +is_a: GO:1902759 ! Mo(VI)-molybdopterin cytosine dinucleotide metabolic process +relationship: has_part GO:0061602 ! molybdenum cofactor cytidylyltransferase activity +created_by: dph +creation_date: 2014-03-06T14:00:43Z + +[Term] +id: GO:1902761 +name: positive regulation of chondrocyte development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] +synonym: "activation of chondrocyte development" NARROW [GOC:TermGenie] +synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie] +synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie] +synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0032332 ! positive regulation of chondrocyte differentiation +is_a: GO:0061181 ! regulation of chondrocyte development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002063 ! chondrocyte development +relationship: positively_regulates GO:0002063 ! chondrocyte development +created_by: mr +creation_date: 2014-03-07T17:45:55Z + +[Term] +id: GO:1902762 +name: regulation of embryonic skeletal joint development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of embryonic skeletal joint development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072498 ! embryonic skeletal joint development +relationship: regulates GO:0072498 ! embryonic skeletal joint development +created_by: mr +creation_date: 2014-03-07T17:46:01Z + +[Term] +id: GO:1902763 +name: negative regulation of embryonic skeletal joint development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] +synonym: "down regulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +synonym: "down-regulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +synonym: "downregulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +synonym: "inhibition of embryonic skeletal joint development" NARROW [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1902762 ! regulation of embryonic skeletal joint development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072498 ! embryonic skeletal joint development +relationship: negatively_regulates GO:0072498 ! embryonic skeletal joint development +created_by: mr +creation_date: 2014-03-07T17:46:07Z + +[Term] +id: GO:1902764 +name: positive regulation of embryonic skeletal joint development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] +synonym: "activation of embryonic skeletal joint development" NARROW [GOC:TermGenie] +synonym: "up regulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +synonym: "up-regulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +synonym: "upregulation of embryonic skeletal joint development" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1902762 ! regulation of embryonic skeletal joint development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072498 ! embryonic skeletal joint development +relationship: positively_regulates GO:0072498 ! embryonic skeletal joint development +created_by: mr +creation_date: 2014-03-07T17:46:13Z + +[Term] +id: GO:1902766 +name: skeletal muscle satellite cell migration +namespace: biological_process +def: "The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells." [GO_REF:0000091, GOC:mr, GOC:TermGenie, PMID:17996437, PMID:19609936] +is_a: GO:0016477 ! cell migration +created_by: mr +creation_date: 2014-03-10T15:20:28Z + +[Term] +id: GO:1902767 +name: isoprenoid biosynthetic process via mevalonate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate." [GO_REF:0000092, GOC:mengo_curators, GOC:TermGenie, PMID:11078528] +synonym: "isoprenoid anabolism via mevalonate" EXACT [GOC:TermGenie] +synonym: "isoprenoid biosynthesis via mevalonate" EXACT [GOC:TermGenie] +synonym: "isoprenoid formation via mevalonate" EXACT [GOC:TermGenie] +synonym: "isoprenoid synthesis via mevalonate" EXACT [GOC:TermGenie] +is_a: GO:0008299 ! isoprenoid biosynthetic process +created_by: tt +creation_date: 2014-03-10T23:45:10Z + +[Term] +id: GO:1902768 +name: isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate." [GO_REF:0000092, GOC:mengo_curators, GOC:TermGenie, PMID:23746261] +synonym: "isoprenoid anabolism via 1-deoxy-D-xylulose 5-phosphate" EXACT [GOC:TermGenie] +synonym: "isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate" EXACT [GOC:TermGenie] +synonym: "isoprenoid formation via 1-deoxy-D-xylulose 5-phosphate" EXACT [GOC:TermGenie] +synonym: "isoprenoid synthesis via 1-deoxy-D-xylulose 5-phosphate" EXACT [GOC:TermGenie] +is_a: GO:0008299 ! isoprenoid biosynthetic process +created_by: tt +creation_date: 2014-03-11T00:09:55Z + +[Term] +id: GO:1902769 +name: regulation of choline O-acetyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:7576634] +synonym: "regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004102 ! choline O-acetyltransferase activity +relationship: regulates GO:0004102 ! choline O-acetyltransferase activity +created_by: mr +creation_date: 2014-03-11T18:54:26Z + +[Term] +id: GO:1902770 +name: negative regulation of choline O-acetyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:7576634] +synonym: "down regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of acetyl-CoA:choline O-acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CHOACTase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of choline acetylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of choline acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of choline O-acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1902769 ! regulation of choline O-acetyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004102 ! choline O-acetyltransferase activity +relationship: negatively_regulates GO:0004102 ! choline O-acetyltransferase activity +created_by: mr +creation_date: 2014-03-11T18:56:50Z + +[Term] +id: GO:1902771 +name: positive regulation of choline O-acetyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:7576634] +synonym: "activation of acetyl-CoA:choline O-acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CHOACTase activity" NARROW [GOC:TermGenie] +synonym: "activation of choline acetylase activity" NARROW [GOC:TermGenie] +synonym: "activation of choline acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of choline O-acetyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acetyl-CoA:choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CHOACTase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of choline acetylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of choline acetyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of choline O-acetyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1902769 ! regulation of choline O-acetyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004102 ! choline O-acetyltransferase activity +relationship: positively_regulates GO:0004102 ! choline O-acetyltransferase activity +created_by: mr +creation_date: 2014-03-11T18:58:39Z + +[Term] +id: GO:1902772 +name: positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway +namespace: biological_process +def: "Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway." [GO_REF:0000060, GOC:TermGenie, PMID:18406331] +synonym: "activation of two-component signal transduction involved in H2O2 mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of histidyl-aspartyl phosphorelay involved in H2O2 mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphorelay signal transduction system involved in H2O2 mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of two-component signal transduction system (phosphorelay) involved in H2O2 mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "stimulation of two-component signal transduction involved in H2O2 mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "stimulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "stimulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of two-component signal transduction involved in H2O2 mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of two-component signal transduction involved in H2O2 mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of two-component signal transduction involved in H2O2 mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0070299 ! positive regulation of phosphorelay signal transduction system +intersection_of: GO:0070299 ! positive regulation of phosphorelay signal transduction system +intersection_of: part_of GO:0071588 ! hydrogen peroxide mediated signaling pathway +relationship: part_of GO:0071588 ! hydrogen peroxide mediated signaling pathway +created_by: al +creation_date: 2014-03-17T11:42:08Z + +[Term] +id: GO:1902773 +name: GTPase activator complex +namespace: cellular_component +def: "A protein complex which is capable of GTPase activator activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16449187] +comment: An example of this is BFA1 in Saccharomyces cerevisiae (P47113) in PMID:16449187 (inferred from direct assay). +is_a: GO:0150005 ! enzyme activator complex +created_by: bhm +creation_date: 2014-03-17T14:26:08Z + +[Term] +id: GO:1902774 +name: late endosome to lysosome transport +namespace: biological_process +def: "The directed movement of substances from late endosome to lysosome." [GO_REF:0000076, GOC:TermGenie, PMID:23949442] +comment: an example of this is snapin in mouse (Q9Z266) in PMID:20920792 inferred from mutant phenotype +synonym: "prevacuolar compartment to lysosome transport" BROAD [GOC:TermGenie] +is_a: GO:0007041 ! lysosomal transport +created_by: pad +creation_date: 2014-03-17T16:32:36Z + +[Term] +id: GO:1902775 +name: mitochondrial large ribosomal subunit assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit." [GO_REF:0000079, GOC:TermGenie, PMID:24206665] +synonym: "39S ribosomal subunit, mitochondrial assembly" NARROW [GOC:TermGenie] +synonym: "39S ribosomal subunit, mitochondrial formation" NARROW [GOC:TermGenie] +synonym: "mitochondrial large ribosomal subunit formation" EXACT [GOC:TermGenie] +is_a: GO:0000027 ! ribosomal large subunit assembly +relationship: part_of GO:0061668 ! mitochondrial ribosome assembly +created_by: mcc +creation_date: 2014-03-18T14:32:19Z + +[Term] +id: GO:1902776 +name: 6-sulfoquinovose(1-) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 6-sulfoquinovose(1-)." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:24463506] +synonym: "6-sulfoquinovose(1-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006082 ! organic acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: dph +creation_date: 2014-03-18T17:45:56Z + +[Term] +id: GO:1902777 +name: 6-sulfoquinovose(1-) catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-)." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:24463506] +synonym: "6-sulfoquinovose(1-) breakdown" EXACT [GOC:TermGenie] +synonym: "6-sulfoquinovose(1-) catabolism" EXACT [GOC:TermGenie] +synonym: "6-sulfoquinovose(1-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0016054 ! organic acid catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:1902776 ! 6-sulfoquinovose(1-) metabolic process +created_by: dph +creation_date: 2014-03-18T17:46:03Z + +[Term] +id: GO:1902778 +name: response to alkane +namespace: biological_process +alt_id: GO:1990373 +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739, PMID:23826995] +synonym: "process resulting in tolerance to alkane" NARROW [] +is_a: GO:0010033 ! response to organic substance + +[Term] +id: GO:1902779 +name: cellular response to alkane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739, PMID:23826995] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T03:18:04Z + +[Term] +id: GO:1902780 +name: response to nonane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739] +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T03:24:50Z + +[Term] +id: GO:1902781 +name: cellular response to nonane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22958739] +is_a: GO:1902779 ! cellular response to alkane +is_a: GO:1902780 ! response to nonane +created_by: tt +creation_date: 2014-03-21T03:25:32Z + +[Term] +id: GO:1902782 +name: response to decane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T12:50:08Z + +[Term] +id: GO:1902783 +name: cellular response to decane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902779 ! cellular response to alkane +is_a: GO:1902782 ! response to decane +created_by: tt +creation_date: 2014-03-21T12:50:14Z + +[Term] +id: GO:1902784 +name: response to undecane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T13:39:06Z + +[Term] +id: GO:1902785 +name: cellular response to undecane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902779 ! cellular response to alkane +is_a: GO:1902784 ! response to undecane +created_by: tt +creation_date: 2014-03-21T13:39:24Z + +[Term] +id: GO:1902786 +name: response to dodecane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T13:41:36Z + +[Term] +id: GO:1902787 +name: cellular response to dodecane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:23826995] +is_a: GO:1902779 ! cellular response to alkane +is_a: GO:1902786 ! response to dodecane +created_by: tt +creation_date: 2014-03-21T13:41:52Z + +[Term] +id: GO:1902788 +name: response to isooctane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22328008] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:1902778 ! response to alkane +created_by: tt +creation_date: 2014-03-21T20:52:51Z + +[Term] +id: GO:1902789 +name: cellular response to isooctane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus." [GO_REF:0000071, GOC:mengo_curators, GOC:TermGenie, PMID:22328008] +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1902779 ! cellular response to alkane +is_a: GO:1902788 ! response to isooctane +created_by: tt +creation_date: 2014-03-21T20:52:58Z + +[Term] +id: GO:1902790 +name: undecan-2-one metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving undecan-2-one." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:4950559] +synonym: "undecan-2-one metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042180 ! cellular ketone metabolic process +created_by: tt +creation_date: 2014-03-22T02:13:01Z + +[Term] +id: GO:1902791 +name: undecan-2-one biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of undecan-2-one." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:4950559] +synonym: "undecan-2-one anabolism" EXACT [GOC:TermGenie] +synonym: "undecan-2-one biosynthesis" EXACT [GOC:TermGenie] +synonym: "undecan-2-one formation" EXACT [GOC:TermGenie] +synonym: "undecan-2-one synthesis" EXACT [GOC:TermGenie] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1902790 ! undecan-2-one metabolic process +created_by: tt +creation_date: 2014-03-22T02:13:07Z + +[Term] +id: GO:1902792 +name: pyrroline-5-carboxylate reductase complex +namespace: cellular_component +def: "A protein complex which is capable of pyrroline-5-carboxylate reductase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:2722838] +comment: An example of this is PYCR1 in human (P32322) in PMID:2722838 (inferred from direct assay). +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2014-03-24T09:55:22Z + +[Term] +id: GO:1902793 +name: glutamate decarboxylase complex +namespace: cellular_component +def: "A protein complex which is capable of glutamate decarboxylase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:17384644] +comment: An example of this is GAD1 in human (Q99259) in PMID:17384644 (inferred from direct assay). +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2014-03-24T10:59:45Z + +[Term] +id: GO:1902794 +name: heterochromatin island assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a heterochromatin island." [GO_REF:0000079, GOC:TermGenie, PMID:24210919] +synonym: "heterochromatin island formation" EXACT [GOC:TermGenie] +is_a: GO:0031507 ! heterochromatin assembly +created_by: mah +creation_date: 2014-03-24T12:46:49Z + +[Term] +id: GO:1902795 +name: heterochromatin domain assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a heterochromatin domain." [GO_REF:0000079, GOC:TermGenie, PMID:24210919] +synonym: "heterochromatin domain formation" EXACT [GOC:TermGenie] +synonym: "HOOD assembly" EXACT [GOC:TermGenie] +synonym: "HOOD formation" EXACT [GOC:TermGenie] +is_a: GO:0031507 ! heterochromatin assembly +created_by: mah +creation_date: 2014-03-24T12:46:56Z + +[Term] +id: GO:1902796 +name: regulation of snoRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of snoRNA processing." [GO_REF:0000058, GOC:TermGenie, PMID:24210919] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:1903323 ! regulation of snoRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043144 ! snoRNA processing +relationship: regulates GO:0043144 ! snoRNA processing +created_by: mah +creation_date: 2014-03-24T12:47:02Z + +[Term] +id: GO:1902797 +name: negative regulation of snoRNA processing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing." [GO_REF:0000058, GOC:TermGenie, PMID:24210919] +synonym: "down regulation of snoRNA processing" EXACT [GOC:TermGenie] +synonym: "down-regulation of snoRNA processing" EXACT [GOC:TermGenie] +synonym: "downregulation of snoRNA processing" EXACT [GOC:TermGenie] +synonym: "inhibition of snoRNA processing" NARROW [GOC:TermGenie] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:1902796 ! regulation of snoRNA processing +is_a: GO:1903324 ! negative regulation of snoRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043144 ! snoRNA processing +relationship: negatively_regulates GO:0043144 ! snoRNA processing +created_by: mah +creation_date: 2014-03-24T12:47:08Z + +[Term] +id: GO:1902798 +name: positive regulation of snoRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of snoRNA processing." [GO_REF:0000058, GOC:TermGenie, PMID:24210919] +synonym: "activation of snoRNA processing" NARROW [GOC:TermGenie] +synonym: "up regulation of snoRNA processing" EXACT [GOC:TermGenie] +synonym: "up-regulation of snoRNA processing" EXACT [GOC:TermGenie] +synonym: "upregulation of snoRNA processing" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:1902796 ! regulation of snoRNA processing +is_a: GO:1903325 ! positive regulation of snoRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043144 ! snoRNA processing +relationship: positively_regulates GO:0043144 ! snoRNA processing +created_by: mah +creation_date: 2014-03-24T12:47:20Z + +[Term] +id: GO:1902799 +name: regulation of phosphodiesterase I activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphodiesterase I activity." [GO_REF:0000059, GOC:TermGenie, PMID:24559510] +synonym: "regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "regulation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PDE I activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphodiesterase activity" BROAD [GOC:TermGenie] +is_a: GO:1905777 ! regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004528 ! phosphodiesterase I activity +relationship: regulates GO:0004528 ! phosphodiesterase I activity +created_by: al +creation_date: 2014-03-25T08:55:48Z + +[Term] +id: GO:1902800 +name: positive regulation of phosphodiesterase I activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity." [GO_REF:0000059, GOC:TermGenie, PMID:24559510] +synonym: "activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" NARROW [GOC:TermGenie] +synonym: "activation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "activation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "activation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "activation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "activation of nucleotide pyrophosphatase/phosphodiesterase I activity" NARROW [GOC:TermGenie] +synonym: "activation of oligonucleate 5'-nucleotidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of orthophosphoric diester phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of PDE I activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphodiesterase I activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PDE I activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "up regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "up regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PDE I activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PDE I activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'-NPDase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'-PDase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'-PDE activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5'NPDE activity" RELATED [GOC:TermGenie] +synonym: "upregulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of exonuclease I activity" RELATED [GOC:TermGenie] +synonym: "upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] +synonym: "upregulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PDE I activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] +is_a: GO:1902799 ! regulation of phosphodiesterase I activity +is_a: GO:1905779 ! positive regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004528 ! phosphodiesterase I activity +relationship: positively_regulates GO:0004528 ! phosphodiesterase I activity +created_by: al +creation_date: 2014-03-25T08:55:54Z + +[Term] +id: GO:1902801 +name: regulation of heterochromatin island assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heterochromatin island assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24210919] +synonym: "regulation of heterochromatin island formation" EXACT [GOC:TermGenie] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902794 ! heterochromatin island assembly +relationship: regulates GO:1902794 ! heterochromatin island assembly +created_by: mah +creation_date: 2014-03-25T14:44:48Z + +[Term] +id: GO:1902802 +name: regulation of heterochromatin domain assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heterochromatin domain assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24210919] +synonym: "regulation of heterochromatin domain formation" EXACT [GOC:TermGenie] +synonym: "regulation of HOOD assembly" EXACT [GOC:TermGenie] +synonym: "regulation of HOOD formation" EXACT [GOC:TermGenie] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902795 ! heterochromatin domain assembly +relationship: regulates GO:1902795 ! heterochromatin domain assembly +created_by: mah +creation_date: 2014-03-25T14:44:54Z + +[Term] +id: GO:1902803 +name: regulation of synaptic vesicle transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23527112] +synonym: "regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +is_a: GO:0051049 ! regulation of transport +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048489 ! synaptic vesicle transport +relationship: regulates GO:0048489 ! synaptic vesicle transport +created_by: kmv +creation_date: 2014-03-25T14:56:34Z + +[Term] +id: GO:1902804 +name: negative regulation of synaptic vesicle transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23527112] +synonym: "down regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1902803 ! regulation of synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048489 ! synaptic vesicle transport +relationship: negatively_regulates GO:0048489 ! synaptic vesicle transport +created_by: kmv +creation_date: 2014-03-25T14:56:40Z + +[Term] +id: GO:1902805 +name: positive regulation of synaptic vesicle transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23527112] +synonym: "activation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "activation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "activation of synaptic vesicle transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle fission" RELATED [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle fusion" RELATED [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1902803 ! regulation of synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048489 ! synaptic vesicle transport +relationship: positively_regulates GO:0048489 ! synaptic vesicle transport +created_by: kmv +creation_date: 2014-03-25T14:56:46Z + +[Term] +id: GO:1902806 +name: regulation of cell cycle G1/S phase transition +namespace: biological_process +def: "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +is_a: GO:1901987 ! regulation of cell cycle phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044843 ! cell cycle G1/S phase transition +relationship: regulates GO:0044843 ! cell cycle G1/S phase transition +created_by: jl +creation_date: 2014-03-26T16:36:14Z + +[Term] +id: GO:1902807 +name: negative regulation of cell cycle G1/S phase transition +namespace: biological_process +def: "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "down regulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +synonym: "downregulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +synonym: "inhibition of cell cycle G1/S phase transition" NARROW [GOC:TermGenie] +is_a: GO:1901988 ! negative regulation of cell cycle phase transition +is_a: GO:1902806 ! regulation of cell cycle G1/S phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044843 ! cell cycle G1/S phase transition +relationship: negatively_regulates GO:0044843 ! cell cycle G1/S phase transition +created_by: jl +creation_date: 2014-03-26T16:36:20Z + +[Term] +id: GO:1902808 +name: positive regulation of cell cycle G1/S phase transition +namespace: biological_process +def: "Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of cell cycle G1/S phase transition" NARROW [GOC:TermGenie] +synonym: "up regulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +synonym: "upregulation of cell cycle G1/S phase transition" EXACT [GOC:TermGenie] +is_a: GO:1901989 ! positive regulation of cell cycle phase transition +is_a: GO:1902806 ! regulation of cell cycle G1/S phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044843 ! cell cycle G1/S phase transition +relationship: positively_regulates GO:0044843 ! cell cycle G1/S phase transition +created_by: jl +creation_date: 2014-03-26T16:36:32Z + +[Term] +id: GO:1902809 +name: regulation of skeletal muscle fiber differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] +is_a: GO:0010830 ! regulation of myotube differentiation +is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098528 ! skeletal muscle fiber differentiation +relationship: regulates GO:0098528 ! skeletal muscle fiber differentiation +created_by: mr +creation_date: 2014-03-26T21:18:26Z + +[Term] +id: GO:1902810 +name: negative regulation of skeletal muscle fiber differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] +synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] +is_a: GO:0010832 ! negative regulation of myotube differentiation +is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation +is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation +relationship: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation +created_by: mr +creation_date: 2014-03-26T21:18:32Z + +[Term] +id: GO:1902811 +name: positive regulation of skeletal muscle fiber differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] +synonym: "activation of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] +is_a: GO:0010831 ! positive regulation of myotube differentiation +is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation +is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation +relationship: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation +created_by: mr +creation_date: 2014-03-26T21:18:38Z + +[Term] +id: GO:1902812 +name: regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10499580] +synonym: "regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +is_a: GO:0030510 ! regulation of BMP signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000380 ! regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: mr +creation_date: 2014-03-26T21:18:44Z + +[Term] +id: GO:1902813 +name: negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10499580] +synonym: "down regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "down regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "down regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "down-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "down-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "down-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "downregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "downregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "downregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "inhibition of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "inhibition of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" NARROW [GOC:TermGenie] +synonym: "inhibition of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "negative regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "negative regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +is_a: GO:0030514 ! negative regulation of BMP signaling pathway +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902812 ! regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +is_a: GO:2000381 ! negative regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: negatively_regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: mr +creation_date: 2014-03-26T21:18:50Z + +[Term] +id: GO:1902814 +name: positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10499580] +synonym: "activation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "activation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" NARROW [GOC:TermGenie] +synonym: "activation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" NARROW [GOC:TermGenie] +synonym: "positive regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "positive regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry" EXACT [GOC:TermGenie] +is_a: GO:0030513 ! positive regulation of BMP signaling pathway +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902812 ! regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +is_a: GO:2000382 ! positive regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +relationship: positively_regulates GO:0003155 ! BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry +created_by: mr +creation_date: 2014-03-26T21:18:56Z + +[Term] +id: GO:1902815 +name: N,N'-diacetylchitobiose import +namespace: biological_process +def: "The directed movement of N,N'-diacetylchitobiose into a cell or organelle." [GO_REF:0000073, GOC:am, GOC:TermGenie, PMID:9405618] +is_a: GO:1901264 ! carbohydrate derivative transport +created_by: tb +creation_date: 2014-03-27T20:58:58Z + +[Term] +id: GO:1902816 +name: regulation of protein localization to microtubule +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] +synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035372 ! protein localization to microtubule +relationship: regulates GO:0035372 ! protein localization to microtubule +created_by: tb +creation_date: 2014-03-27T22:07:12Z + +[Term] +id: GO:1902817 +name: negative regulation of protein localization to microtubule +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] +synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to microtubule" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to microtubule" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] +is_a: GO:1902816 ! regulation of protein localization to microtubule +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035372 ! protein localization to microtubule +relationship: negatively_regulates GO:0035372 ! protein localization to microtubule +created_by: tb +creation_date: 2014-03-27T22:07:18Z + +[Term] +id: GO:1902818 +name: ethyl acetate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ethyl acetate." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16013377] +synonym: "ethyl acetate metabolism" EXACT [GOC:TermGenie] +synonym: "ethyl ethanoate metabolic process" EXACT [] +is_a: GO:1900619 ! acetate ester metabolic process +created_by: tt +creation_date: 2014-03-30T20:26:47Z + +[Term] +id: GO:1902819 +name: ethyl acetate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ethyl acetate." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16013377] +synonym: "ethyl acetate anabolism" EXACT [GOC:TermGenie] +synonym: "ethyl acetate biosynthesis" EXACT [GOC:TermGenie] +synonym: "ethyl acetate formation" EXACT [GOC:TermGenie] +synonym: "ethyl acetate synthesis" EXACT [GOC:TermGenie] +synonym: "ethyl ethanoate biosynthetic process" EXACT [] +is_a: GO:1900620 ! acetate ester biosynthetic process +is_a: GO:1902818 ! ethyl acetate metabolic process +created_by: tt +creation_date: 2014-03-30T20:26:53Z + +[Term] +id: GO:1902820 +name: 1-undecene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-undecene." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16013377] +synonym: "1-undecene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0043449 ! cellular alkene metabolic process +created_by: tt +creation_date: 2014-03-31T02:50:48Z + +[Term] +id: GO:1902821 +name: 1-undecene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-undecene." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16013377] +synonym: "1-undecene anabolism" EXACT [GOC:TermGenie] +synonym: "1-undecene biosynthesis" EXACT [GOC:TermGenie] +synonym: "1-undecene formation" EXACT [GOC:TermGenie] +synonym: "1-undecene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0043450 ! alkene biosynthetic process +is_a: GO:1902820 ! 1-undecene metabolic process +created_by: tt +creation_date: 2014-03-31T02:51:19Z + +[Term] +id: GO:1902822 +name: regulation of late endosome to lysosome transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of late endosome to lysosome transport." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:23949442] +synonym: "regulation of prevacuolar compartment to lysosome transport" BROAD [GOC:TermGenie] +is_a: GO:1903335 ! regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902774 ! late endosome to lysosome transport +relationship: regulates GO:1902774 ! late endosome to lysosome transport +created_by: pad +creation_date: 2014-03-31T10:08:38Z + +[Term] +id: GO:1902823 +name: negative regulation of late endosome to lysosome transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:23949442] +synonym: "down regulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +synonym: "downregulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +synonym: "inhibition of late endosome to lysosome transport" NARROW [GOC:TermGenie] +is_a: GO:1902822 ! regulation of late endosome to lysosome transport +is_a: GO:1903336 ! negative regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902774 ! late endosome to lysosome transport +relationship: negatively_regulates GO:1902774 ! late endosome to lysosome transport +created_by: pad +creation_date: 2014-03-31T10:08:51Z + +[Term] +id: GO:1902824 +name: positive regulation of late endosome to lysosome transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:23949442] +synonym: "activation of late endosome to lysosome transport" NARROW [GOC:TermGenie] +synonym: "up regulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +synonym: "upregulation of late endosome to lysosome transport" EXACT [GOC:TermGenie] +is_a: GO:1902822 ! regulation of late endosome to lysosome transport +is_a: GO:1903337 ! positive regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902774 ! late endosome to lysosome transport +relationship: positively_regulates GO:1902774 ! late endosome to lysosome transport +created_by: pad +creation_date: 2014-03-31T10:08:57Z + +[Term] +id: GO:1902829 +name: regulation of spinal cord association neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +synonym: "regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0021527 ! spinal cord association neuron differentiation +relationship: regulates GO:0021527 ! spinal cord association neuron differentiation +created_by: mr +creation_date: 2014-03-31T17:10:55Z + +[Term] +id: GO:1902830 +name: negative regulation of spinal cord association neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +synonym: "down regulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of spinal cord association neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of spinal cord dorsal interneuron differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:1902829 ! regulation of spinal cord association neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021527 ! spinal cord association neuron differentiation +relationship: negatively_regulates GO:0021527 ! spinal cord association neuron differentiation +created_by: mr +creation_date: 2014-03-31T17:11:55Z + +[Term] +id: GO:1902831 +name: positive regulation of spinal cord association neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +synonym: "activation of spinal cord association neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of spinal cord dorsal interneuron differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of spinal cord association neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of spinal cord dorsal interneuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:1902829 ! regulation of spinal cord association neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0021527 ! spinal cord association neuron differentiation +relationship: positively_regulates GO:0021527 ! spinal cord association neuron differentiation +created_by: mr +creation_date: 2014-03-31T17:12:38Z + +[Term] +id: GO:1902832 +name: negative regulation of cell proliferation in dorsal spinal cord +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +synonym: "down regulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +synonym: "inhibition of cell proliferation in dorsal spinal cord" NARROW [GOC:TermGenie] +is_a: GO:0021921 ! regulation of cell proliferation in dorsal spinal cord +is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010456 ! cell proliferation in dorsal spinal cord +relationship: negatively_regulates GO:0010456 ! cell proliferation in dorsal spinal cord +created_by: mr +creation_date: 2014-03-31T17:42:50Z + +[Term] +id: GO:1902833 +name: positive regulation of cell proliferation in dorsal spinal cord +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +synonym: "activation of cell proliferation in dorsal spinal cord" NARROW [GOC:TermGenie] +synonym: "up regulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +synonym: "upregulation of cell proliferation in dorsal spinal cord" EXACT [GOC:TermGenie] +is_a: GO:0021921 ! regulation of cell proliferation in dorsal spinal cord +is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010456 ! cell proliferation in dorsal spinal cord +relationship: positively_regulates GO:0010456 ! cell proliferation in dorsal spinal cord +created_by: mr +creation_date: 2014-03-31T17:43:33Z + +[Term] +id: GO:1902834 +name: regulation of proline import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proline import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +synonym: "regulation of proline import into cell" EXACT [] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:0070881 ! regulation of proline transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905647 ! proline import across plasma membrane +relationship: regulates GO:1905647 ! proline import across plasma membrane +created_by: mah +creation_date: 2014-04-01T13:44:00Z + +[Term] +id: GO:1902835 +name: negative regulation of proline import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +synonym: "down regulation of proline import into cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of proline import into cell" EXACT [GOC:TermGenie] +synonym: "downregulation of proline import into cell" EXACT [GOC:TermGenie] +synonym: "inhibition of proline import into cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of proline import into cell" EXACT [] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1902834 ! regulation of proline import across plasma membrane +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905647 ! proline import across plasma membrane +relationship: negatively_regulates GO:1905647 ! proline import across plasma membrane +created_by: mah +creation_date: 2014-04-01T13:44:06Z + +[Term] +id: GO:1902836 +name: positive regulation of proline import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proline import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +synonym: "activation of proline import into cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of proline import into cell" EXACT [] +synonym: "up regulation of proline import into cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of proline import into cell" EXACT [GOC:TermGenie] +synonym: "upregulation of proline import into cell" EXACT [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1902834 ! regulation of proline import across plasma membrane +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905647 ! proline import across plasma membrane +relationship: positively_regulates GO:1905647 ! proline import across plasma membrane +created_by: mah +creation_date: 2014-04-01T13:44:20Z + +[Term] +id: GO:1902838 +name: regulation of nuclear migration along microtubule +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear movement, microtubule-mediated" BROAD [GOC:TermGenie] +synonym: "regulation of nucleus migration" BROAD [GOC:TermGenie] +synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +is_a: GO:1902513 ! regulation of organelle transport along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030473 ! nuclear migration along microtubule +relationship: regulates GO:0030473 ! nuclear migration along microtubule +created_by: vw +creation_date: 2014-04-01T13:50:23Z + +[Term] +id: GO:1902839 +name: negative regulation of nuclear migration along microtubule +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "inhibition of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear migration along microtubule" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] +synonym: "inhibition of transport of nucleus by microtubules" NARROW [GOC:TermGenie] +synonym: "inhibition of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] +synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:1902838 ! regulation of nuclear migration along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030473 ! nuclear migration along microtubule +relationship: negatively_regulates GO:0030473 ! nuclear migration along microtubule +created_by: vw +creation_date: 2014-04-01T13:50:29Z + +[Term] +id: GO:1902840 +name: positive regulation of nuclear migration along microtubule +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "activation of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] +synonym: "activation of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] +synonym: "activation of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] +synonym: "activation of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] +synonym: "activation of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] +synonym: "activation of nuclear migration along microtubule" NARROW [GOC:TermGenie] +synonym: "activation of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] +synonym: "activation of transport of nucleus by microtubules" NARROW [GOC:TermGenie] +synonym: "activation of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] +synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] +synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] +synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:1902838 ! regulation of nuclear migration along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030473 ! nuclear migration along microtubule +relationship: positively_regulates GO:0030473 ! nuclear migration along microtubule +created_by: vw +creation_date: 2014-04-01T13:50:35Z + +[Term] +id: GO:1902841 +name: regulation of netrin-activated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:24004945] +synonym: "regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038007 ! netrin-activated signaling pathway +relationship: regulates GO:0038007 ! netrin-activated signaling pathway +created_by: kmv +creation_date: 2014-04-01T15:24:46Z + +[Term] +id: GO:1902842 +name: negative regulation of netrin-activated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:24004945] +synonym: "down regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of netrin signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of netrin-activated signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of netrin-activated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of netrin-activated signalling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of netrin-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902841 ! regulation of netrin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038007 ! netrin-activated signaling pathway +relationship: negatively_regulates GO:0038007 ! netrin-activated signaling pathway +created_by: kmv +creation_date: 2014-04-01T15:25:33Z + +[Term] +id: GO:1902843 +name: positive regulation of netrin-activated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:24004945] +synonym: "activation of netrin signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of netrin-activated signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "activation of netrin-activated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of netrin-activated signalling pathway" NARROW [GOC:TermGenie] +synonym: "activation of netrin-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of netrin signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of netrin-activated signal transduction pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of netrin-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of netrin-activated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of netrin-mediated signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902841 ! regulation of netrin-activated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038007 ! netrin-activated signaling pathway +relationship: positively_regulates GO:0038007 ! netrin-activated signaling pathway +created_by: kmv +creation_date: 2014-04-01T15:25:53Z + +[Term] +id: GO:1902844 +name: positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway +namespace: biological_process +def: "A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation." [GO_REF:0000063, GOC:mr, GOC:TermGenie, PMID:11262869] +synonym: "activation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0050768 ! negative regulation of neurogenesis +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:1902829 ! regulation of spinal cord association neuron differentiation +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: negatively_regulates GO:0100067 ! positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway +relationship: negatively_regulates GO:0100067 ! positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway +created_by: mr +creation_date: 2014-04-01T15:28:30Z + +[Term] +id: GO:1902845 +name: negative regulation of mitotic spindle elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "down regulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "down regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic spindle elongation" NARROW [GOC:TermGenie] +synonym: "inhibition of spindle elongation during mitosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0032888 ! regulation of mitotic spindle elongation +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000022 ! mitotic spindle elongation +relationship: negatively_regulates GO:0000022 ! mitotic spindle elongation +created_by: vw +creation_date: 2014-04-02T08:43:28Z + +[Term] +id: GO:1902846 +name: positive regulation of mitotic spindle elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "activation of mitotic spindle elongation" NARROW [GOC:TermGenie] +synonym: "activation of spindle elongation during mitosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle elongation during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0032888 ! regulation of mitotic spindle elongation +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +is_a: GO:0110028 ! positive regulation of mitotic spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000022 ! mitotic spindle elongation +relationship: positively_regulates GO:0000022 ! mitotic spindle elongation +created_by: vw +creation_date: 2014-04-02T08:43:34Z + +[Term] +id: GO:1902847 +name: regulation of neuronal signal transduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuronal signal transduction." [GO_REF:0000058, GOC:sjp, GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0023041 ! neuronal signal transduction +relationship: regulates GO:0023041 ! neuronal signal transduction +created_by: sjp +creation_date: 2014-04-02T10:11:12Z + +[Term] +id: GO:1902848 +name: negative regulation of neuronal signal transduction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction." [GO_REF:0000058, GOC:sjp, GOC:TermGenie] +synonym: "down regulation of neuronal signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuronal signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of neuronal signal transduction" EXACT [GOC:TermGenie] +synonym: "inhibition of neuronal signal transduction" NARROW [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1902847 ! regulation of neuronal signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0023041 ! neuronal signal transduction +relationship: negatively_regulates GO:0023041 ! neuronal signal transduction +created_by: sjp +creation_date: 2014-04-02T10:11:18Z + +[Term] +id: GO:1902849 +name: positive regulation of neuronal signal transduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuronal signal transduction." [GO_REF:0000058, GOC:sjp, GOC:TermGenie] +synonym: "activation of neuronal signal transduction" NARROW [GOC:TermGenie] +synonym: "up regulation of neuronal signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuronal signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of neuronal signal transduction" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1902847 ! regulation of neuronal signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0023041 ! neuronal signal transduction +relationship: positively_regulates GO:0023041 ! neuronal signal transduction +created_by: sjp +creation_date: 2014-04-02T10:11:24Z + +[Term] +id: GO:1902850 +name: microtubule cytoskeleton organization involved in mitosis +namespace: biological_process +def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626] +synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie] +synonym: "microtubule cytoskeleton organization and biogenesis involved in mitosis" RELATED [GOC:TermGenie] +synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie] +is_a: GO:0000226 ! microtubule cytoskeleton organization +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0000226 ! microtubule cytoskeleton organization +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: vw +creation_date: 2014-04-02T14:19:38Z + +[Term] +id: GO:1902852 +name: regulation of nuclear migration during mitotic telophase +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +is_a: GO:1902838 ! regulation of nuclear migration along microtubule +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090561 ! nuclear migration during mitotic telophase +relationship: regulates GO:0090561 ! nuclear migration during mitotic telophase +created_by: vw +creation_date: 2014-04-02T15:35:34Z + +[Term] +id: GO:1902853 +name: negative regulation of nuclear migration during mitotic telophase +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "down regulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +synonym: "inhibition of nuclear migration during mitotic telophase" NARROW [GOC:TermGenie] +is_a: GO:1902839 ! negative regulation of nuclear migration along microtubule +is_a: GO:1902852 ! regulation of nuclear migration during mitotic telophase +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090561 ! nuclear migration during mitotic telophase +relationship: negatively_regulates GO:0090561 ! nuclear migration during mitotic telophase +created_by: vw +creation_date: 2014-04-02T15:35:56Z + +[Term] +id: GO:1902854 +name: positive regulation of nuclear migration during mitotic telophase +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] +synonym: "activation of nuclear migration during mitotic telophase" NARROW [GOC:TermGenie] +synonym: "up regulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear migration during mitotic telophase" EXACT [GOC:TermGenie] +is_a: GO:1902840 ! positive regulation of nuclear migration along microtubule +is_a: GO:1902852 ! regulation of nuclear migration during mitotic telophase +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090561 ! nuclear migration during mitotic telophase +relationship: positively_regulates GO:0090561 ! nuclear migration during mitotic telophase +created_by: vw +creation_date: 2014-04-02T15:36:06Z + +[Term] +id: GO:1902855 +name: regulation of non-motile cilium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of non-motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:kmv, GOC:TermGenie, PMID:23807208] +synonym: "regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "regulation of nonmotile primary cilium assembly" RELATED [] +synonym: "regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +is_a: GO:1902017 ! regulation of cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905515 ! non-motile cilium assembly +relationship: regulates GO:1905515 ! non-motile cilium assembly +created_by: kmv +creation_date: 2014-04-02T15:41:57Z + +[Term] +id: GO:1902856 +name: negative regulation of non-motile cilium assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:kmv, GOC:TermGenie, PMID:23807208] +synonym: "down regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of immotile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of nonmotile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory cilium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of nonmotile primary cilium assembly" RELATED [] +synonym: "negative regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +is_a: GO:1902018 ! negative regulation of cilium assembly +is_a: GO:1902855 ! regulation of non-motile cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905515 ! non-motile cilium assembly +relationship: negatively_regulates GO:1905515 ! non-motile cilium assembly +created_by: kmv +creation_date: 2014-04-02T15:42:17Z + +[Term] +id: GO:1902857 +name: positive regulation of non-motile cilium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:kmv, GOC:TermGenie, PMID:23807208] +synonym: "activation of immotile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "activation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "activation of nonmotile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "activation of sensory cilium assembly" NARROW [GOC:TermGenie] +synonym: "activation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of nonmotile primary cilium assembly" RELATED [] +synonym: "positive regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of immotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of nonmotile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of nonmotile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of sensory cilium assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of sensory cilium biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0045724 ! positive regulation of cilium assembly +is_a: GO:1902855 ! regulation of non-motile cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905515 ! non-motile cilium assembly +relationship: positively_regulates GO:1905515 ! non-motile cilium assembly +created_by: kmv +creation_date: 2014-04-02T15:42:31Z + +[Term] +id: GO:1902858 +name: propionyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving propionyl-CoA." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:15514053] +synonym: "propionyl-CoA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0035337 ! fatty-acyl-CoA metabolic process +created_by: tt +creation_date: 2014-04-03T03:10:17Z + +[Term] +id: GO:1902859 +name: propionyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of propionyl-CoA." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:15514053] +synonym: "propionyl-CoA breakdown" EXACT [GOC:TermGenie] +synonym: "propionyl-CoA catabolism" EXACT [GOC:TermGenie] +synonym: "propionyl-CoA degradation" EXACT [GOC:TermGenie] +is_a: GO:0036115 ! fatty-acyl-CoA catabolic process +is_a: GO:1902858 ! propionyl-CoA metabolic process +created_by: tt +creation_date: 2014-04-03T03:10:23Z + +[Term] +id: GO:1902860 +name: propionyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of propionyl-CoA." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:15514053] +synonym: "propionyl-CoA anabolism" EXACT [GOC:TermGenie] +synonym: "propionyl-CoA biosynthesis" EXACT [GOC:TermGenie] +synonym: "propionyl-CoA formation" EXACT [GOC:TermGenie] +synonym: "propionyl-CoA synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046949 ! fatty-acyl-CoA biosynthetic process +is_a: GO:1902858 ! propionyl-CoA metabolic process +created_by: tt +creation_date: 2014-04-03T03:10:29Z + +[Term] +id: GO:1902862 +name: obsolete glycerol catabolic process to glycerone phosphate +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol to glycerone phosphate." [GO_REF:0000093, GOC:dph, GOC:TermGenie, ISBN:0201090910] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "glycerol breakdown to glycerone phosphate" EXACT [GOC:TermGenie] +synonym: "glycerol catabolic process to glycerone phosphate" EXACT [] +synonym: "glycerol catabolism to glycerone phosphate" EXACT [GOC:TermGenie] +synonym: "glycerol degradation to glycerone phosphate" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dph +creation_date: 2014-04-03T14:42:01Z + +[Term] +id: GO:1902863 +name: regulation of embryonic camera-type eye development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031076 ! embryonic camera-type eye development +relationship: regulates GO:0031076 ! embryonic camera-type eye development +created_by: mr +creation_date: 2014-04-03T15:24:00Z + +[Term] +id: GO:1902864 +name: negative regulation of embryonic camera-type eye development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "inhibition of embryonic camera-type eye development" NARROW [GOC:TermGenie] +synonym: "inhibition of embryonic eye development" NARROW [GOC:TermGenie] +synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1902863 ! regulation of embryonic camera-type eye development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031076 ! embryonic camera-type eye development +relationship: negatively_regulates GO:0031076 ! embryonic camera-type eye development +created_by: mr +creation_date: 2014-04-03T15:24:06Z + +[Term] +id: GO:1902865 +name: positive regulation of embryonic camera-type eye development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "activation of embryonic camera-type eye development" NARROW [GOC:TermGenie] +synonym: "activation of embryonic eye development" NARROW [GOC:TermGenie] +synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie] +synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] +synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1902863 ! regulation of embryonic camera-type eye development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031076 ! embryonic camera-type eye development +relationship: positively_regulates GO:0031076 ! embryonic camera-type eye development +created_by: mr +creation_date: 2014-04-03T15:24:12Z + +[Term] +id: GO:1902866 +name: regulation of retina development in camera-type eye +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "regulation of retinal development" RELATED [GOC:TermGenie] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060041 ! retina development in camera-type eye +relationship: regulates GO:0060041 ! retina development in camera-type eye +created_by: mr +creation_date: 2014-04-03T15:24:17Z + +[Term] +id: GO:1902867 +name: negative regulation of retina development in camera-type eye +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "down regulation of retinal development" RELATED [GOC:TermGenie] +synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "down-regulation of retinal development" RELATED [GOC:TermGenie] +synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "downregulation of retinal development" RELATED [GOC:TermGenie] +synonym: "inhibition of retina development in camera-style eye" NARROW [GOC:TermGenie] +synonym: "inhibition of retina development in camera-type eye" NARROW [GOC:TermGenie] +synonym: "inhibition of retinal development" RELATED [GOC:TermGenie] +synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "negative regulation of retinal development" RELATED [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1902866 ! regulation of retina development in camera-type eye +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060041 ! retina development in camera-type eye +relationship: negatively_regulates GO:0060041 ! retina development in camera-type eye +created_by: mr +creation_date: 2014-04-03T15:24:23Z + +[Term] +id: GO:1902868 +name: positive regulation of retina development in camera-type eye +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "activation of retina development in camera-style eye" NARROW [GOC:TermGenie] +synonym: "activation of retina development in camera-type eye" NARROW [GOC:TermGenie] +synonym: "activation of retinal development" RELATED [GOC:TermGenie] +synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "positive regulation of retinal development" RELATED [GOC:TermGenie] +synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "up regulation of retinal development" RELATED [GOC:TermGenie] +synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinal development" RELATED [GOC:TermGenie] +synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] +synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] +synonym: "upregulation of retinal development" RELATED [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1902866 ! regulation of retina development in camera-type eye +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060041 ! retina development in camera-type eye +relationship: positively_regulates GO:0060041 ! retina development in camera-type eye +created_by: mr +creation_date: 2014-04-03T15:24:29Z + +[Term] +id: GO:1902869 +name: regulation of amacrine cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amacrine cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045664 ! regulation of neuron differentiation +is_a: GO:0061074 ! regulation of neural retina development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035881 ! amacrine cell differentiation +relationship: regulates GO:0035881 ! amacrine cell differentiation +created_by: mr +creation_date: 2014-04-03T15:24:35Z + +[Term] +id: GO:1902870 +name: negative regulation of amacrine cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "down regulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of amacrine cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of amacrine neuron differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:0061076 ! negative regulation of neural retina development +is_a: GO:1902869 ! regulation of amacrine cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035881 ! amacrine cell differentiation +relationship: negatively_regulates GO:0035881 ! amacrine cell differentiation +created_by: mr +creation_date: 2014-04-03T15:24:40Z + +[Term] +id: GO:1902871 +name: positive regulation of amacrine cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "activation of amacrine cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of amacrine neuron differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of amacrine cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of amacrine neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:0061075 ! positive regulation of neural retina development +is_a: GO:1902869 ! regulation of amacrine cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035881 ! amacrine cell differentiation +relationship: positively_regulates GO:0035881 ! amacrine cell differentiation +created_by: mr +creation_date: 2014-04-03T15:24:46Z + +[Term] +id: GO:1902872 +name: regulation of horizontal cell localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of horizontal cell localization." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +is_a: GO:0032879 ! regulation of localization +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0061074 ! regulation of neural retina development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035852 ! horizontal cell localization +relationship: regulates GO:0035852 ! horizontal cell localization +created_by: mr +creation_date: 2014-04-03T15:24:58Z + +[Term] +id: GO:1902873 +name: negative regulation of horizontal cell localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "down regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "down regulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "down regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "down regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "downregulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "downregulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "downregulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "inhibition of horizontal cell localisation" NARROW [GOC:TermGenie] +synonym: "inhibition of horizontal cell localization" NARROW [GOC:TermGenie] +synonym: "inhibition of horizontal cell positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of laminar positioning of retinal horizontal cell" NARROW [GOC:TermGenie] +synonym: "inhibition of retinal horizontal cell positioning" NARROW [GOC:TermGenie] +synonym: "negative regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "negative regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0061076 ! negative regulation of neural retina development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1902872 ! regulation of horizontal cell localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035852 ! horizontal cell localization +relationship: negatively_regulates GO:0035852 ! horizontal cell localization +created_by: mr +creation_date: 2014-04-03T15:25:03Z + +[Term] +id: GO:1902874 +name: positive regulation of horizontal cell localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of horizontal cell localization." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "activation of horizontal cell localisation" NARROW [GOC:TermGenie] +synonym: "activation of horizontal cell localization" NARROW [GOC:TermGenie] +synonym: "activation of horizontal cell positioning" NARROW [GOC:TermGenie] +synonym: "activation of laminar positioning of retinal horizontal cell" NARROW [GOC:TermGenie] +synonym: "activation of retinal horizontal cell positioning" NARROW [GOC:TermGenie] +synonym: "positive regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "positive regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "up regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "up regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of horizontal cell localisation" EXACT [GOC:TermGenie] +synonym: "upregulation of horizontal cell localization" EXACT [GOC:TermGenie] +synonym: "upregulation of horizontal cell positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of laminar positioning of retinal horizontal cell" EXACT [GOC:TermGenie] +synonym: "upregulation of retinal horizontal cell positioning" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0061075 ! positive regulation of neural retina development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1902872 ! regulation of horizontal cell localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035852 ! horizontal cell localization +relationship: positively_regulates GO:0035852 ! horizontal cell localization +created_by: mr +creation_date: 2014-04-03T15:25:09Z + +[Term] +id: GO:1902875 +name: regulation of embryonic pattern specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "regulation of embryonic pattern biosynthesis" BROAD [GOC:TermGenie] +synonym: "regulation of embryonic pattern formation" BROAD [GOC:TermGenie] +synonym: "regulation of ventral/lateral system" RELATED [GOC:TermGenie] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009880 ! embryonic pattern specification +relationship: regulates GO:0009880 ! embryonic pattern specification +created_by: mr +creation_date: 2014-04-03T15:25:15Z + +[Term] +id: GO:1902876 +name: negative regulation of embryonic pattern specification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "down regulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "downregulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "inhibition of embryonic pattern specification" NARROW [GOC:TermGenie] +synonym: "inhibition of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "negative regulation of ventral/lateral system" RELATED [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1902875 ! regulation of embryonic pattern specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009880 ! embryonic pattern specification +relationship: negatively_regulates GO:0009880 ! embryonic pattern specification +created_by: mr +creation_date: 2014-04-03T15:25:20Z + +[Term] +id: GO:1902877 +name: positive regulation of embryonic pattern specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] +synonym: "activation of embryonic pattern specification" NARROW [GOC:TermGenie] +synonym: "activation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "positive regulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "up regulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of ventral/lateral system" RELATED [GOC:TermGenie] +synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie] +synonym: "upregulation of ventral/lateral system" RELATED [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1902875 ! regulation of embryonic pattern specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009880 ! embryonic pattern specification +relationship: positively_regulates GO:0009880 ! embryonic pattern specification +created_by: mr +creation_date: 2014-04-03T15:25:26Z + +[Term] +id: GO:1902878 +name: obsolete regulation of BMP signaling pathway involved in spinal cord association neuron specification +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mr +creation_date: 2014-04-03T15:25:32Z + +[Term] +id: GO:1902879 +name: obsolete negative regulation of BMP signaling pathway involved in spinal cord association neuron specification +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "down regulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "downregulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "downregulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "downregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "downregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "inhibition of BMP signaling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "inhibition of BMP signalling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "inhibition of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "inhibition of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "negative regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "negative regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "negative regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mr +creation_date: 2014-04-03T15:25:38Z + +[Term] +id: GO:1902880 +name: obsolete positive regulation of BMP signaling pathway involved in spinal cord association neuron specification +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:21730158] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "activation of BMP signaling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "activation of BMP signalling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "activation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "activation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" NARROW [GOC:TermGenie] +synonym: "positive regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "positive regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "positive regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "upregulation of BMP signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "upregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +synonym: "upregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: mr +creation_date: 2014-04-03T15:25:43Z + +[Term] +id: GO:1902882 +name: regulation of response to oxidative stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006979 ! response to oxidative stress +relationship: regulates GO:0006979 ! response to oxidative stress +created_by: kmv +creation_date: 2014-04-03T20:29:52Z + +[Term] +id: GO:1902883 +name: negative regulation of response to oxidative stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] +synonym: "down regulation of response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "inhibition of response to oxidative stress" NARROW [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1902882 ! regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006979 ! response to oxidative stress +relationship: negatively_regulates GO:0006979 ! response to oxidative stress +created_by: kmv +creation_date: 2014-04-03T20:30:20Z + +[Term] +id: GO:1902884 +name: positive regulation of response to oxidative stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16899554] +synonym: "activation of response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "up regulation of response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1902882 ! regulation of response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006979 ! response to oxidative stress +relationship: positively_regulates GO:0006979 ! response to oxidative stress +created_by: kmv +creation_date: 2014-04-03T20:30:47Z + +[Term] +id: GO:1902885 +name: regulation of proteasome-activating ATPase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity." [GO_REF:0000059, GOC:di, GOC:TermGenie, PMID:23995839] +synonym: "regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +is_a: GO:0043462 ! regulation of ATPase activity +is_a: GO:0061136 ! regulation of proteasomal protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036402 ! proteasome-activating ATPase activity +relationship: regulates GO:0036402 ! proteasome-activating ATPase activity +created_by: di +creation_date: 2014-04-04T17:35:23Z + +[Term] +id: GO:1902886 +name: negative regulation of proteasome-activating ATPase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity." [GO_REF:0000059, GOC:di, GOC:TermGenie, PMID:23995839] +synonym: "down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "down regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "down regulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "downregulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "downregulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of proteasomal ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "inhibition of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "inhibition of proteasome-activating ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1902885 ! regulation of proteasome-activating ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036402 ! proteasome-activating ATPase activity +relationship: negatively_regulates GO:0036402 ! proteasome-activating ATPase activity +created_by: di +creation_date: 2014-04-04T17:35:30Z + +[Term] +id: GO:1902887 +name: positive regulation of proteasome-activating ATPase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity." [GO_REF:0000059, GOC:di, GOC:TermGenie, PMID:23995839] +synonym: "activation of ATPase involved in positive regulation of proteasomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of proteasomal ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "activation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "activation of proteasome-activating ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "up regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "up regulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasomal ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of proteasome channel gating activity" NARROW [GOC:TermGenie] +synonym: "upregulation of proteasome channel opening activity" NARROW [GOC:TermGenie] +synonym: "upregulation of proteasome-activating ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:1901800 ! positive regulation of proteasomal protein catabolic process +is_a: GO:1902885 ! regulation of proteasome-activating ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036402 ! proteasome-activating ATPase activity +relationship: positively_regulates GO:0036402 ! proteasome-activating ATPase activity +created_by: di +creation_date: 2014-04-04T17:35:36Z + +[Term] +id: GO:1902888 +name: protein localization to astral microtubule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an astral microtubule." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:16054030] +synonym: "protein localisation in astral microtubule" EXACT [GOC:TermGenie] +synonym: "protein localisation to astral microtubule" EXACT [GOC:TermGenie] +synonym: "protein localization in astral microtubule" EXACT [GOC:TermGenie] +is_a: GO:1902889 ! protein localization to spindle microtubule +is_a: GO:1905755 ! protein localization to cytoplasmic microtubule +created_by: kmv +creation_date: 2014-04-05T21:26:34Z + +[Term] +id: GO:1902889 +name: protein localization to spindle microtubule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a spindle microtubule." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:16054030] +synonym: "protein localisation in spindle microtubule" EXACT [GOC:TermGenie] +synonym: "protein localisation to spindle microtubule" EXACT [GOC:TermGenie] +synonym: "protein localization in spindle microtubule" EXACT [GOC:TermGenie] +is_a: GO:0035372 ! protein localization to microtubule +created_by: kmv +creation_date: 2014-04-05T21:31:39Z + +[Term] +id: GO:1902890 +name: regulation of root hair elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of root hair elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22329353] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:1903429 ! regulation of cell maturation +is_a: GO:1903888 ! regulation of plant epidermal cell differentiation +is_a: GO:2000067 ! regulation of root morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048767 ! root hair elongation +relationship: regulates GO:0048767 ! root hair elongation +created_by: als +creation_date: 2014-04-07T13:46:40Z + +[Term] +id: GO:1902891 +name: negative regulation of root hair elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22329353] +synonym: "down regulation of root hair elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of root hair elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of root hair elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of root hair elongation" NARROW [GOC:TermGenie] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1902890 ! regulation of root hair elongation +is_a: GO:1903430 ! negative regulation of cell maturation +is_a: GO:1903889 ! negative regulation of plant epidermal cell differentiation +is_a: GO:1905422 ! negative regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048767 ! root hair elongation +relationship: negatively_regulates GO:0048767 ! root hair elongation +created_by: als +creation_date: 2014-04-07T13:46:47Z + +[Term] +id: GO:1902892 +name: positive regulation of root hair elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of root hair elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22329353] +synonym: "activation of root hair elongation" NARROW [GOC:TermGenie] +synonym: "up regulation of root hair elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of root hair elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of root hair elongation" EXACT [GOC:TermGenie] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1902890 ! regulation of root hair elongation +is_a: GO:1903431 ! positive regulation of cell maturation +is_a: GO:1903890 ! positive regulation of plant epidermal cell differentiation +is_a: GO:1905423 ! positive regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048767 ! root hair elongation +relationship: positively_regulates GO:0048767 ! root hair elongation +created_by: als +creation_date: 2014-04-07T13:46:53Z + +[Term] +id: GO:1902893 +name: regulation of pri-miRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24699545] +synonym: "regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +relationship: regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +created_by: dph +creation_date: 2014-04-08T13:22:08Z + +[Term] +id: GO:1902894 +name: negative regulation of pri-miRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24699545] +synonym: "down regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of pri-miRNA transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1902893 ! regulation of pri-miRNA transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +relationship: negatively_regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +created_by: dph +creation_date: 2014-04-08T13:22:14Z + +[Term] +id: GO:1902895 +name: positive regulation of pri-miRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24699545] +synonym: "activation of pri-miRNA transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [] +synonym: "up regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of pri-miRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1902893 ! regulation of pri-miRNA transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +relationship: positively_regulates GO:0061614 ! pri-miRNA transcription by RNA polymerase II +created_by: dph +creation_date: 2014-04-08T13:22:20Z + +[Term] +id: GO:1902896 +name: terminal web assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a terminal web." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, pmid:21949650] +synonym: "terminal web formation" EXACT [GOC:TermGenie] +is_a: GO:0030866 ! cortical actin cytoskeleton organization +is_a: GO:0070925 ! organelle assembly +created_by: kmv +creation_date: 2014-04-08T15:15:25Z + +[Term] +id: GO:1902897 +name: regulation of postsynaptic density protein 95 clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:10570482] +synonym: "regulation of Dlg4 clustering" EXACT [GOC:TermGenie] +synonym: "regulation of post-synaptic density protein 95 clustering" EXACT [GOC:TermGenie] +synonym: "regulation of PSD-95 clustering" EXACT [GOC:TermGenie] +is_a: GO:1901626 ! regulation of postsynaptic membrane organization +is_a: GO:1905475 ! regulation of protein localization to membrane +is_a: GO:1905874 ! regulation of postsynaptic density organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097119 ! postsynaptic density protein 95 clustering +relationship: regulates GO:0097119 ! postsynaptic density protein 95 clustering +created_by: als +creation_date: 2014-04-09T14:52:08Z + +[Term] +id: GO:1902898 +name: fatty acid methyl ester metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fatty acid methyl ester." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16570218] +synonym: "FAME metabolic process" EXACT [] +synonym: "fatty acid methyl ester metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006629 ! lipid metabolic process +created_by: tt +creation_date: 2014-04-11T03:08:34Z + +[Term] +id: GO:1902899 +name: fatty acid methyl ester biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fatty acid methyl ester." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:16570218] +synonym: "FAME biosynthetic process" EXACT [] +synonym: "fatty acid methyl ester anabolism" EXACT [GOC:TermGenie] +synonym: "fatty acid methyl ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "fatty acid methyl ester formation" EXACT [GOC:TermGenie] +synonym: "fatty acid methyl ester synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:1902898 ! fatty acid methyl ester metabolic process +created_by: tt +creation_date: 2014-04-11T03:08:40Z + +[Term] +id: GO:1902900 +name: gut granule assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a gut granule." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, pmid:17202409] +synonym: "gut granule biogenesis" EXACT [pmid:17202409] +synonym: "gut granule formation" EXACT [GOC:TermGenie] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0070925 ! organelle assembly +created_by: kmv +creation_date: 2014-04-14T14:28:17Z + +[Term] +id: GO:1902901 +name: positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, pmid:17888400] +synonym: "activation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "activation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress" NARROW [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:1990170 ! stress response to cadmium ion +relationship: part_of GO:1990170 ! stress response to cadmium ion +created_by: kmv +creation_date: 2014-04-14T18:03:42Z + +[Term] +id: GO:1902902 +name: negative regulation of autophagosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly." [GO_REF:0000058, GOC:als, GOC:autophagy, GOC:TermGenie, PMID:21975012] +synonym: "down regulation of autophagic vacuole assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of autophagic vacuole formation" RELATED [GOC:TermGenie] +synonym: "down regulation of autophagosome biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of autophagosome formation" EXACT [GOC:TermGenie] +synonym: "down regulation of PAS formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of autophagic vacuole assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of autophagic vacuole formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of autophagosome biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of autophagosome formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of PAS formation" NARROW [GOC:TermGenie] +synonym: "downregulation of autophagic vacuole assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of autophagic vacuole formation" RELATED [GOC:TermGenie] +synonym: "downregulation of autophagosome biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of autophagosome formation" EXACT [GOC:TermGenie] +synonym: "downregulation of PAS formation" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagic vacuole assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagic vacuole formation" RELATED [GOC:TermGenie] +synonym: "inhibition of autophagosome biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of autophagosome formation" NARROW [GOC:TermGenie] +synonym: "inhibition of PAS formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of autophagic vacuole assembly" EXACT [GOC:autophagy] +synonym: "negative regulation of autophagic vacuole formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of autophagosome biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of autophagosome formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of PAS formation" NARROW [GOC:TermGenie] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:2000785 ! regulation of autophagosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000045 ! autophagosome assembly +relationship: negatively_regulates GO:0000045 ! autophagosome assembly +created_by: als +creation_date: 2014-04-15T10:37:40Z + +[Term] +id: GO:1902903 +name: regulation of supramolecular fiber organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] +comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro +synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097435 ! supramolecular fiber organization +relationship: regulates GO:0097435 ! supramolecular fiber organization +created_by: rl +creation_date: 2014-04-15T16:46:36Z + +[Term] +id: GO:1902904 +name: negative regulation of supramolecular fiber organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] +comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro +synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie] +synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie] +synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie] +synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097435 ! supramolecular fiber organization +relationship: negatively_regulates GO:0097435 ! supramolecular fiber organization +created_by: rl +creation_date: 2014-04-15T16:46:42Z + +[Term] +id: GO:1902905 +name: positive regulation of supramolecular fiber organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] +comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro +synonym: "activation of fibril organisation" NARROW [GOC:TermGenie] +synonym: "activation of fibril organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie] +synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie] +synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie] +synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097435 ! supramolecular fiber organization +relationship: positively_regulates GO:0097435 ! supramolecular fiber organization +created_by: rl +creation_date: 2014-04-15T16:46:48Z + +[Term] +id: GO:1902906 +name: proteasome storage granule assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule." [GO_REF:0000079, GOC:di, GOC:TermGenie, PMID:23690178] +synonym: "proteasome storage granule formation" EXACT [GOC:TermGenie] +synonym: "PSG assembly" EXACT [GOC:TermGenie] +synonym: "PSG formation" EXACT [GOC:TermGenie] +is_a: GO:0043248 ! proteasome assembly +created_by: di +creation_date: 2014-04-16T01:59:41Z + +[Term] +id: GO:1902907 +name: proteasome storage granule disassembly +namespace: biological_process +def: "The disaggregation of a proteasome storage granule into its constituent components." [GO_REF:0000079, GOC:di, GOC:TermGenie, PMID:23690178] +synonym: "PSG disassembly" EXACT [GOC:TermGenie] +is_a: GO:1903009 ! proteasome complex disassembly +created_by: di +creation_date: 2014-04-16T01:59:47Z + +[Term] +id: GO:1902908 +name: regulation of melanosome transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of melanosome transport." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23334344] +is_a: GO:0051049 ! regulation of transport +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032402 ! melanosome transport +relationship: regulates GO:0032402 ! melanosome transport +created_by: als +creation_date: 2014-04-17T11:40:16Z + +[Term] +id: GO:1902909 +name: negative regulation of melanosome transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23334344] +synonym: "down regulation of melanosome transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of melanosome transport" EXACT [GOC:TermGenie] +synonym: "downregulation of melanosome transport" EXACT [GOC:TermGenie] +synonym: "inhibition of melanosome transport" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1902908 ! regulation of melanosome transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032402 ! melanosome transport +relationship: negatively_regulates GO:0032402 ! melanosome transport +created_by: als +creation_date: 2014-04-17T11:40:28Z + +[Term] +id: GO:1902910 +name: positive regulation of melanosome transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of melanosome transport." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23334344] +synonym: "activation of melanosome transport" NARROW [GOC:TermGenie] +synonym: "up regulation of melanosome transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of melanosome transport" EXACT [GOC:TermGenie] +synonym: "upregulation of melanosome transport" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1902908 ! regulation of melanosome transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032402 ! melanosome transport +relationship: positively_regulates GO:0032402 ! melanosome transport +created_by: als +creation_date: 2014-04-17T11:40:34Z + +[Term] +id: GO:1902911 +name: protein kinase complex +namespace: cellular_component +def: "A protein complex which is capable of protein kinase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:24606918] +comment: An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay). +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: bhm +creation_date: 2014-04-17T13:52:40Z + +[Term] +id: GO:1902912 +name: pyruvate kinase complex +namespace: cellular_component +def: "A protein complex which is capable of pyruvate kinase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:24606918] +comment: An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay). +is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups +created_by: bhm +creation_date: 2014-04-17T14:11:41Z + +[Term] +id: GO:1902913 +name: positive regulation of neuroepithelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506] +synonym: "activation of neuroepithelial cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060563 ! neuroepithelial cell differentiation +relationship: positively_regulates GO:0060563 ! neuroepithelial cell differentiation +created_by: mr +creation_date: 2014-04-18T21:06:42Z + +[Term] +id: GO:1902914 +name: regulation of protein polyubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein polyubiquitination." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23645667] +synonym: "regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031396 ! regulation of protein ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000209 ! protein polyubiquitination +relationship: regulates GO:0000209 ! protein polyubiquitination +created_by: di +creation_date: 2014-04-18T22:09:52Z + +[Term] +id: GO:1902915 +name: negative regulation of protein polyubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23645667] +synonym: "down regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "down regulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "downregulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "downregulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "inhibition of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "inhibition of protein polyubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of protein polyubiquitinylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein polyubiquitylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031397 ! negative regulation of protein ubiquitination +is_a: GO:1902914 ! regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000209 ! protein polyubiquitination +relationship: negatively_regulates GO:0000209 ! protein polyubiquitination +created_by: di +creation_date: 2014-04-18T22:09:58Z + +[Term] +id: GO:1902916 +name: positive regulation of protein polyubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein polyubiquitination." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23645667] +synonym: "activation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "activation of protein polyubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein polyubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of protein polyubiquitylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "up regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "up regulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +synonym: "upregulation of polyubiquitin" RELATED [GOC:TermGenie] +synonym: "upregulation of protein polyubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polyubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polyubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031398 ! positive regulation of protein ubiquitination +is_a: GO:1902914 ! regulation of protein polyubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000209 ! protein polyubiquitination +relationship: positively_regulates GO:0000209 ! protein polyubiquitination +created_by: di +creation_date: 2014-04-18T22:10:04Z + +[Term] +id: GO:1902917 +name: positive regulation of mating projection assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mating projection assembly." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:12455985] +synonym: "activation of mating projection assembly" NARROW [GOC:TermGenie] +synonym: "activation of mating projection biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of mating projection biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of mating projection assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of mating projection biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of mating projection assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of mating projection biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of mating projection assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of mating projection biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0031139 ! positive regulation of conjugation with cellular fusion +is_a: GO:0031383 ! regulation of mating projection assembly +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031382 ! mating projection formation +relationship: positively_regulates GO:0031382 ! mating projection formation +created_by: di +creation_date: 2014-04-20T11:18:03Z + +[Term] +id: GO:1902918 +name: poly(5-hydroxyvalerate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(5-hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(5-hydroxyvalerate) metabolism" EXACT [GOC:TermGenie] +is_a: GO:1902920 ! poly(hydroxyvalerate) metabolic process +created_by: tt +creation_date: 2014-04-21T18:47:06Z + +[Term] +id: GO:1902919 +name: poly(5-hydroxyvalerate) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(5-hydroxyvalerate) anabolism" EXACT [GOC:TermGenie] +synonym: "poly(5-hydroxyvalerate) biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(5-hydroxyvalerate) formation" EXACT [GOC:TermGenie] +synonym: "poly(5-hydroxyvalerate) synthesis" EXACT [GOC:TermGenie] +is_a: GO:1902918 ! poly(5-hydroxyvalerate) metabolic process +is_a: GO:1902921 ! poly(hydroxyvalerate) biosynthetic process +created_by: tt +creation_date: 2014-04-21T18:47:12Z + +[Term] +id: GO:1902920 +name: poly(hydroxyvalerate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(hydroxyvalerate) metabolism" EXACT [GOC:TermGenie] +is_a: GO:1901440 ! poly(hydroxyalkanoate) metabolic process +created_by: tt +creation_date: 2014-04-21T19:12:32Z + +[Term] +id: GO:1902921 +name: poly(hydroxyvalerate) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(hydroxyvalerate) anabolism" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyvalerate) biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyvalerate) formation" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyvalerate) synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901441 ! poly(hydroxyalkanoate) biosynthetic process +is_a: GO:1902920 ! poly(hydroxyvalerate) metabolic process +created_by: tt +creation_date: 2014-04-21T19:12:38Z + +[Term] +id: GO:1902922 +name: poly(3-hydroxyvalerate) metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving poly(3-hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(3-hydroxyvalerate) metabolism" EXACT [GOC:TermGenie] +is_a: GO:1902920 ! poly(hydroxyvalerate) metabolic process +created_by: tt +creation_date: 2014-04-21T19:13:56Z + +[Term] +id: GO:1902923 +name: poly(3-hydroxyvalerate) biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate)." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21705209] +synonym: "poly(3-hydroxyvalerate) anabolism" EXACT [GOC:TermGenie] +synonym: "poly(3-hydroxyvalerate) biosynthesis" EXACT [GOC:TermGenie] +synonym: "poly(3-hydroxyvalerate) formation" EXACT [GOC:TermGenie] +synonym: "poly(3-hydroxyvalerate) synthesis" EXACT [GOC:TermGenie] +is_a: GO:1902921 ! poly(hydroxyvalerate) biosynthetic process +is_a: GO:1902922 ! poly(3-hydroxyvalerate) metabolic process +created_by: tt +creation_date: 2014-04-21T19:14:02Z + +[Term] +id: GO:1902924 +name: poly(hydroxyalkanoate) biosynthetic process from glucose +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose." [GO_REF:0000092, GOC:mengo_curators, GOC:TermGenie, PMID:24425304] +synonym: "poly(hydroxyalkanoate) anabolism from glucose" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) biosynthesis from glucose" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) formation from glucose" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) synthesis from glucose" EXACT [GOC:TermGenie] +is_a: GO:0006006 ! glucose metabolic process +is_a: GO:1901441 ! poly(hydroxyalkanoate) biosynthetic process +created_by: tt +creation_date: 2014-04-21T22:49:07Z + +[Term] +id: GO:1902925 +name: poly(hydroxyalkanoate) biosynthetic process from fatty acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid." [GO_REF:0000092, GOC:mengo_curators, GOC:TermGenie, PMID:21129764] +synonym: "poly(hydroxyalkanoate) anabolism from fatty acid" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) biosynthesis from fatty acid" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) formation from fatty acid" EXACT [GOC:TermGenie] +synonym: "poly(hydroxyalkanoate) synthesis from fatty acid" EXACT [GOC:TermGenie] +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:1901441 ! poly(hydroxyalkanoate) biosynthetic process +created_by: tt +creation_date: 2014-04-21T22:53:59Z + +[Term] +id: GO:1902926 +name: inulin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving inulin." [GO_REF:0000068, GOC:TermGenie, PMID:23104410] +comment: SUC2 in S. cerevisiae strain JZ1C in PMID:23104410. +synonym: "inulin metabolism" EXACT [GOC:TermGenie] +is_a: GO:0010145 ! fructan metabolic process +created_by: se +creation_date: 2014-04-21T23:54:33Z + +[Term] +id: GO:1902927 +name: inulin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of inulin." [GO_REF:0000068, GOC:TermGenie, PMID:23104410] +comment: SUC2 in S. cerevisiae strain JZ1C in PMID:23104410. +synonym: "inulin breakdown" EXACT [GOC:TermGenie] +synonym: "inulin catabolism" EXACT [GOC:TermGenie] +synonym: "inulin degradation" EXACT [GOC:TermGenie] +is_a: GO:0010147 ! fructan catabolic process +is_a: GO:1902926 ! inulin metabolic process +created_by: se +creation_date: 2014-04-21T23:54:45Z + +[Term] +id: GO:1902928 +name: inulin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of inulin." [GO_REF:0000068, GOC:TermGenie, PMID:23104410] +comment: SUC2 in S. cerevisiae strain JZ1C in PMID:23104410. +synonym: "inulin anabolism" EXACT [GOC:TermGenie] +synonym: "inulin biosynthesis" EXACT [GOC:TermGenie] +synonym: "inulin formation" EXACT [GOC:TermGenie] +synonym: "inulin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010146 ! fructan biosynthetic process +is_a: GO:1902926 ! inulin metabolic process +created_by: se +creation_date: 2014-04-21T23:54:51Z + +[Term] +id: GO:1902929 +name: plasma membrane of growing cell tip +namespace: cellular_component +def: "Any plasma membrane part that is part of a growing cell tip." [GO_REF:0000064, GOC:TermGenie, PMID:17085965] +synonym: "growing cell tip plasma membrane part" EXACT [GOC:TermGenie] +synonym: "plasma membrane part of growing cell end" EXACT [GOC:TermGenie] +synonym: "plasma membrane part of growing cell tip" EXACT [GOC:TermGenie] +is_a: GO:0031520 ! plasma membrane of cell tip +intersection_of: GO:0098590 ! plasma membrane region +intersection_of: part_of GO:0035838 ! growing cell tip +relationship: part_of GO:0035838 ! growing cell tip +created_by: mah +creation_date: 2014-04-22T16:02:06Z + +[Term] +id: GO:1902930 +name: regulation of alcohol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] +synonym: "regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of solventogenesis" BROAD [] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046165 ! alcohol biosynthetic process +relationship: regulates GO:0046165 ! alcohol biosynthetic process +created_by: tt +creation_date: 2014-04-22T21:55:03Z + +[Term] +id: GO:1902931 +name: negative regulation of alcohol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] +synonym: "down regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "down regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "downregulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of alcohol anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of alcohol biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of alcohol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of alcohol formation" NARROW [GOC:TermGenie] +synonym: "inhibition of alcohol synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of solventogenesis" BROAD [] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046165 ! alcohol biosynthetic process +relationship: negatively_regulates GO:0046165 ! alcohol biosynthetic process +created_by: tt +creation_date: 2014-04-22T21:55:13Z + +[Term] +id: GO:1902932 +name: positive regulation of alcohol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process." [GO_REF:0000058, GOC:mengo_curators, GOC:TermGenie, PMID:23332010] +synonym: "activation of alcohol anabolism" NARROW [GOC:TermGenie] +synonym: "activation of alcohol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of alcohol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of alcohol formation" NARROW [GOC:TermGenie] +synonym: "activation of alcohol synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of solventogenesis" BROAD [] +synonym: "up regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of alcohol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of alcohol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of alcohol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of alcohol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046165 ! alcohol biosynthetic process +relationship: positively_regulates GO:0046165 ! alcohol biosynthetic process +created_by: tt +creation_date: 2014-04-22T21:55:19Z + +[Term] +id: GO:1902933 +name: isopentenol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving isopentenol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:17693564] +synonym: "isopentenol metabolism" EXACT [GOC:TermGenie] +is_a: GO:1901615 ! organic hydroxy compound metabolic process +created_by: tt +creation_date: 2014-04-24T16:51:35Z + +[Term] +id: GO:1902934 +name: isopentenol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of isopentenol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:17693564] +synonym: "isopentenol anabolism" EXACT [GOC:TermGenie] +synonym: "isopentenol biosynthesis" EXACT [GOC:TermGenie] +synonym: "isopentenol formation" EXACT [GOC:TermGenie] +synonym: "isopentenol synthesis" EXACT [GOC:TermGenie] +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:1902933 ! isopentenol metabolic process +created_by: tt +creation_date: 2014-04-24T16:51:42Z + +[Term] +id: GO:1902935 +name: protein localization to septin ring +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a septin ring." [GO_REF:0000087, GOC:TermGenie, PMID:16325501] +synonym: "protein localisation in septin ring" EXACT [GOC:TermGenie] +synonym: "protein localisation to septin ring" EXACT [GOC:TermGenie] +synonym: "protein localization in septin ring" EXACT [GOC:TermGenie] +is_a: GO:0044380 ! protein localization to cytoskeleton +is_a: GO:0072697 ! protein localization to cell cortex +created_by: mah +creation_date: 2014-04-25T13:08:17Z + +[Term] +id: GO:1902936 +name: phosphatidylinositol bisphosphate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphatidylinositol bisphosphate." [GO_REF:0000067, GOC:bhm, GOC:TermGenie, PMID:18690034] +comment: An example of this is KCNJ2 in human (P63252) in PMID:18690034 (inferred from direct assay) +is_a: GO:1901981 ! phosphatidylinositol phosphate binding +created_by: bhm +creation_date: 2014-04-25T15:14:12Z + +[Term] +id: GO:1902937 +name: inward rectifier potassium channel complex +namespace: cellular_component +def: "A protein complex which is capable of inward rectifier potassium channel activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16834334] +comment: An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay). +is_a: GO:0008076 ! voltage-gated potassium channel complex +created_by: bhm +creation_date: 2014-04-25T15:18:41Z + +[Term] +id: GO:1902938 +name: regulation of intracellular calcium activated chloride channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22946059] +is_a: GO:0010359 ! regulation of anion channel activity +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +is_a: GO:2001225 ! regulation of chloride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005229 ! intracellular calcium activated chloride channel activity +relationship: regulates GO:0005229 ! intracellular calcium activated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:49:08Z + +[Term] +id: GO:1902939 +name: negative regulation of intracellular calcium activated chloride channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22946059] +synonym: "down regulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of intracellular calcium activated chloride channel activity" NARROW [GOC:TermGenie] +is_a: GO:0010360 ! negative regulation of anion channel activity +is_a: GO:1902938 ! regulation of intracellular calcium activated chloride channel activity +is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport +is_a: GO:2001226 ! negative regulation of chloride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005229 ! intracellular calcium activated chloride channel activity +relationship: negatively_regulates GO:0005229 ! intracellular calcium activated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:49:14Z + +[Term] +id: GO:1902940 +name: positive regulation of intracellular calcium activated chloride channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22946059] +synonym: "activation of intracellular calcium activated chloride channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular calcium activated chloride channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901529 ! positive regulation of anion channel activity +is_a: GO:1902938 ! regulation of intracellular calcium activated chloride channel activity +is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005229 ! intracellular calcium activated chloride channel activity +relationship: positively_regulates GO:0005229 ! intracellular calcium activated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:49:20Z + +[Term] +id: GO:1902941 +name: regulation of voltage-gated chloride channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22006324] +synonym: "regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +is_a: GO:0010359 ! regulation of anion channel activity +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +is_a: GO:2001225 ! regulation of chloride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005247 ! voltage-gated chloride channel activity +relationship: regulates GO:0005247 ! voltage-gated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:55:31Z + +[Term] +id: GO:1902942 +name: negative regulation of voltage-gated chloride channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22006324] +synonym: "down regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage gated chloride channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-dependent chloride channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated chloride channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +is_a: GO:0010360 ! negative regulation of anion channel activity +is_a: GO:1902941 ! regulation of voltage-gated chloride channel activity +is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport +is_a: GO:2001226 ! negative regulation of chloride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005247 ! voltage-gated chloride channel activity +relationship: negatively_regulates GO:0005247 ! voltage-gated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:55:37Z + +[Term] +id: GO:1902943 +name: positive regulation of voltage-gated chloride channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22006324] +synonym: "activation of voltage gated chloride channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-dependent chloride channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated chloride channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901529 ! positive regulation of anion channel activity +is_a: GO:1902941 ! regulation of voltage-gated chloride channel activity +is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005247 ! voltage-gated chloride channel activity +relationship: positively_regulates GO:0005247 ! voltage-gated chloride channel activity +created_by: als +creation_date: 2014-04-28T08:55:43Z + +[Term] +id: GO:1902944 +name: aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +namespace: molecular_function +def: "Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process." [GO_REF:0000061, GOC:sjp, GOC:TermGenie, PMID:10206644, PMID:24577224] +synonym: "aspartate protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "aspartate protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartate protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "aspartate protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "aspartate protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartate protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "aspartic protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "aspartic protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartic protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "aspartic protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "aspartic protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartic protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "aspartyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "aspartyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "aspartyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "aspartyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "aspartyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "carboxyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +is_a: GO:0004190 ! aspartic-type endopeptidase activity +intersection_of: GO:0004190 ! aspartic-type endopeptidase activity +intersection_of: part_of GO:0042987 ! amyloid precursor protein catabolic process +relationship: part_of GO:0042987 ! amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-02T07:59:42Z + +[Term] +id: GO:1902945 +name: metalloendopeptidase activity involved in amyloid precursor protein catabolic process +namespace: molecular_function +def: "Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process." [GO_REF:0000061, GOC:sjp, GOC:TermGenie, PMID:14598310, PMID:17855360] +synonym: "metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "metalloendoprotease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "metalloendoproteinase activity involved in APP catabolism" NARROW [GOC:TermGenie] +xref: Reactome:R-HSA-9010034 "ADAM10:Zn2+:TSPANs cleaves APP(18-770)" +is_a: GO:0004222 ! metalloendopeptidase activity +intersection_of: GO:0004222 ! metalloendopeptidase activity +intersection_of: part_of GO:0042987 ! amyloid precursor protein catabolic process +relationship: part_of GO:0042987 ! amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-02T08:13:04Z + +[Term] +id: GO:1902946 +name: protein localization to early endosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an early endosome." [GO_REF:0000087, GOC:sjp, GOC:TermGenie, PMID:22621900] +synonym: "protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "protein localization in early endosome" EXACT [GOC:TermGenie] +is_a: GO:0036010 ! protein localization to endosome +created_by: sjp +creation_date: 2014-05-02T08:26:00Z + +[Term] +id: GO:1902947 +name: regulation of tau-protein kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tau-protein kinase activity." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780] +synonym: "regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:tau-protein O-phosphotransferase activity" BROAD [GOC:TermGenie] +synonym: "regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "regulation of GSK" RELATED [GOC:TermGenie] +synonym: "regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of STK31" RELATED [GOC:TermGenie] +synonym: "regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of TPK" RELATED [GOC:TermGenie] +synonym: "regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "regulation of TTK" RELATED [GOC:TermGenie] +is_a: GO:0045859 ! regulation of protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050321 ! tau-protein kinase activity +relationship: regulates GO:0050321 ! tau-protein kinase activity +property_value: RO:0002161 NCBITaxon:4751 +created_by: sjp +creation_date: 2014-05-02T08:43:27Z + +[Term] +id: GO:1902948 +name: negative regulation of tau-protein kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780] +synonym: "down regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "down regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "down regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "down regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "down regulation of GSK" RELATED [GOC:TermGenie] +synonym: "down regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of STK31" RELATED [GOC:TermGenie] +synonym: "down regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "down regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "down regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of TPK" RELATED [GOC:TermGenie] +synonym: "down regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "down regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "down regulation of TTK" RELATED [GOC:TermGenie] +synonym: "down-regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "down-regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "down-regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of GSK" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of STK31" RELATED [GOC:TermGenie] +synonym: "down-regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of TPK" RELATED [GOC:TermGenie] +synonym: "down-regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "down-regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "down-regulation of TTK" RELATED [GOC:TermGenie] +synonym: "downregulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "downregulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "downregulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "downregulation of GSK" RELATED [GOC:TermGenie] +synonym: "downregulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of STK31" RELATED [GOC:TermGenie] +synonym: "downregulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "downregulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "downregulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of TPK" RELATED [GOC:TermGenie] +synonym: "downregulation of TPK I" RELATED [GOC:TermGenie] +synonym: "downregulation of TPK II" RELATED [GOC:TermGenie] +synonym: "downregulation of TTK" RELATED [GOC:TermGenie] +synonym: "inhibition of [Tau protein] kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "inhibition of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "inhibition of glycogen synthase kinase-3beta activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GSK" RELATED [GOC:TermGenie] +synonym: "inhibition of protein tau kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of STK31" RELATED [GOC:TermGenie] +synonym: "inhibition of tau kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tau protein kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tau-protein kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of TPK" RELATED [GOC:TermGenie] +synonym: "inhibition of TPK I" RELATED [GOC:TermGenie] +synonym: "inhibition of TPK II" RELATED [GOC:TermGenie] +synonym: "inhibition of TTK" RELATED [GOC:TermGenie] +synonym: "negative regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "negative regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "negative regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of GSK" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of STK31" RELATED [GOC:TermGenie] +synonym: "negative regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of TPK" RELATED [GOC:TermGenie] +synonym: "negative regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "negative regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "negative regulation of TTK" RELATED [GOC:TermGenie] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:1902947 ! regulation of tau-protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050321 ! tau-protein kinase activity +relationship: negatively_regulates GO:0050321 ! tau-protein kinase activity +property_value: RO:0002161 NCBITaxon:4751 +created_by: sjp +creation_date: 2014-05-02T08:43:32Z + +[Term] +id: GO:1902949 +name: positive regulation of tau-protein kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780] +synonym: "activation of [Tau protein] kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "activation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "activation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "activation of glycogen synthase kinase-3beta activity" NARROW [GOC:TermGenie] +synonym: "activation of GSK" RELATED [GOC:TermGenie] +synonym: "activation of protein tau kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of STK31" RELATED [GOC:TermGenie] +synonym: "activation of tau kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of tau protein kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of tau-protein kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "activation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "activation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of TPK" RELATED [GOC:TermGenie] +synonym: "activation of TPK I" RELATED [GOC:TermGenie] +synonym: "activation of TPK II" RELATED [GOC:TermGenie] +synonym: "activation of TTK" RELATED [GOC:TermGenie] +synonym: "positive regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "positive regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "positive regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of GSK" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of STK31" RELATED [GOC:TermGenie] +synonym: "positive regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of TPK" RELATED [GOC:TermGenie] +synonym: "positive regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "positive regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "positive regulation of TTK" RELATED [GOC:TermGenie] +synonym: "up regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "up regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "up regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "up regulation of GSK" RELATED [GOC:TermGenie] +synonym: "up regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of STK31" RELATED [GOC:TermGenie] +synonym: "up regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "up regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "up regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of TPK" RELATED [GOC:TermGenie] +synonym: "up regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "up regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "up regulation of TTK" RELATED [GOC:TermGenie] +synonym: "up-regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "up-regulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "up-regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of GSK" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of STK31" RELATED [GOC:TermGenie] +synonym: "up-regulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of TPK" RELATED [GOC:TermGenie] +synonym: "up-regulation of TPK I" RELATED [GOC:TermGenie] +synonym: "up-regulation of TPK II" RELATED [GOC:TermGenie] +synonym: "up-regulation of TTK" RELATED [GOC:TermGenie] +synonym: "upregulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cdk5/p20" RELATED [GOC:TermGenie] +synonym: "upregulation of CDK5/p23" RELATED [GOC:TermGenie] +synonym: "upregulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] +synonym: "upregulation of GSK" RELATED [GOC:TermGenie] +synonym: "upregulation of protein tau kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of STK31" RELATED [GOC:TermGenie] +synonym: "upregulation of tau kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tau protein kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tau-protein kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] +synonym: "upregulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] +synonym: "upregulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of TPK" RELATED [GOC:TermGenie] +synonym: "upregulation of TPK I" RELATED [GOC:TermGenie] +synonym: "upregulation of TPK II" RELATED [GOC:TermGenie] +synonym: "upregulation of TTK" RELATED [GOC:TermGenie] +is_a: GO:0045860 ! positive regulation of protein kinase activity +is_a: GO:1902947 ! regulation of tau-protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050321 ! tau-protein kinase activity +relationship: positively_regulates GO:0050321 ! tau-protein kinase activity +property_value: RO:0002161 NCBITaxon:4751 +created_by: sjp +creation_date: 2014-05-02T08:43:38Z + +[Term] +id: GO:1902950 +name: regulation of dendritic spine maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendritic spine maintenance." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24328732] +is_a: GO:0099175 ! regulation of postsynapse organization +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097062 ! dendritic spine maintenance +relationship: regulates GO:0097062 ! dendritic spine maintenance +created_by: sjp +creation_date: 2014-05-02T08:48:47Z + +[Term] +id: GO:1902951 +name: negative regulation of dendritic spine maintenance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24328732] +synonym: "down regulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +synonym: "inhibition of dendritic spine maintenance" NARROW [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:1902950 ! regulation of dendritic spine maintenance +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097062 ! dendritic spine maintenance +relationship: negatively_regulates GO:0097062 ! dendritic spine maintenance +created_by: sjp +creation_date: 2014-05-02T08:48:53Z + +[Term] +id: GO:1902952 +name: positive regulation of dendritic spine maintenance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24328732] +synonym: "activation of dendritic spine maintenance" NARROW [GOC:TermGenie] +synonym: "up regulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +synonym: "up-regulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +synonym: "upregulation of dendritic spine maintenance" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:1902950 ! regulation of dendritic spine maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097062 ! dendritic spine maintenance +relationship: positively_regulates GO:0097062 ! dendritic spine maintenance +created_by: sjp +creation_date: 2014-05-02T08:48:59Z + +[Term] +id: GO:1902953 +name: positive regulation of ER to Golgi vesicle-mediated transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:17855360] +synonym: "activation of endoplasmic reticulum to Golgi transport" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum to Golgi vesicle-mediated transport" NARROW [GOC:TermGenie] +synonym: "activation of ER to Golgi transport" NARROW [GOC:TermGenie] +synonym: "activation of ER to Golgi vesicle-mediated transport" NARROW [GOC:TermGenie] +synonym: "activation of rough endoplasmic reticulum to cis-Golgi transport" NARROW [GOC:TermGenie] +synonym: "activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" NARROW [GOC:TermGenie] +synonym: "activation of rough ER to cis-Golgi transport" NARROW [GOC:TermGenie] +synonym: "activation of rough ER to cis-Golgi vesicle-mediated transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum to Golgi transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER to Golgi transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of rough endoplasmic reticulum to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of rough ER to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of rough ER to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum to Golgi transport" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up regulation of ER to Golgi transport" EXACT [GOC:TermGenie] +synonym: "up regulation of ER to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up regulation of rough endoplasmic reticulum to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up regulation of rough ER to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "up regulation of rough ER to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum to Golgi transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER to Golgi transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of rough endoplasmic reticulum to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of rough ER to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of rough ER to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum to Golgi transport" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "upregulation of ER to Golgi transport" EXACT [GOC:TermGenie] +synonym: "upregulation of ER to Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "upregulation of rough endoplasmic reticulum to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +synonym: "upregulation of rough ER to cis-Golgi transport" EXACT [GOC:TermGenie] +synonym: "upregulation of rough ER to cis-Golgi vesicle-mediated transport" EXACT [GOC:TermGenie] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +relationship: positively_regulates GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: sjp +creation_date: 2014-05-02T08:59:18Z + +[Term] +id: GO:1902954 +name: regulation of early endosome to recycling endosome transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:22621900] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061502 ! early endosome to recycling endosome transport +relationship: regulates GO:0061502 ! early endosome to recycling endosome transport +created_by: sjp +creation_date: 2014-05-02T09:06:23Z + +[Term] +id: GO:1902955 +name: positive regulation of early endosome to recycling endosome transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:22621900] +synonym: "activation of early endosome to recycling endosome transport" NARROW [GOC:TermGenie] +synonym: "up regulation of early endosome to recycling endosome transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of early endosome to recycling endosome transport" EXACT [GOC:TermGenie] +synonym: "upregulation of early endosome to recycling endosome transport" EXACT [GOC:TermGenie] +is_a: GO:1902954 ! regulation of early endosome to recycling endosome transport +is_a: GO:1903651 ! positive regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061502 ! early endosome to recycling endosome transport +relationship: positively_regulates GO:0061502 ! early endosome to recycling endosome transport +created_by: sjp +creation_date: 2014-05-02T09:06:29Z + +[Term] +id: GO:1902956 +name: regulation of mitochondrial electron transport, NADH to ubiquinone +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23530063] +synonym: "regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +is_a: GO:1905446 ! regulation of mitochondrial ATP synthesis coupled electron transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +relationship: regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +created_by: dph +creation_date: 2014-05-02T15:30:12Z + +[Term] +id: GO:1902957 +name: negative regulation of mitochondrial electron transport, NADH to ubiquinone +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23530063] +synonym: "down regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "down regulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "down-regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "down-regulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "downregulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "downregulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "inhibition of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "inhibition of mitochondrial electron transport, NADH to ubiquinone" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidative phosphorylation, NADH to ubiquinone" NARROW [GOC:TermGenie] +synonym: "negative regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "negative regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +is_a: GO:1902956 ! regulation of mitochondrial electron transport, NADH to ubiquinone +is_a: GO:1905447 ! negative regulation of mitochondrial ATP synthesis coupled electron transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +relationship: negatively_regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +created_by: dph +creation_date: 2014-05-02T15:30:18Z + +[Term] +id: GO:1902958 +name: positive regulation of mitochondrial electron transport, NADH to ubiquinone +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23530063] +synonym: "activation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "activation of mitochondrial electron transport, NADH to ubiquinone" NARROW [GOC:TermGenie] +synonym: "activation of oxidative phosphorylation, NADH to ubiquinone" NARROW [GOC:TermGenie] +synonym: "positive regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "positive regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "up regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "up regulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "up-regulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "up-regulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "upregulation of complex I (NADH to ubiquinone)" RELATED [GOC:TermGenie] +synonym: "upregulation of mitochondrial electron transport, NADH to ubiquinone" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidative phosphorylation, NADH to ubiquinone" EXACT [GOC:TermGenie] +is_a: GO:1902956 ! regulation of mitochondrial electron transport, NADH to ubiquinone +is_a: GO:1905448 ! positive regulation of mitochondrial ATP synthesis coupled electron transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +relationship: positively_regulates GO:0006120 ! mitochondrial electron transport, NADH to ubiquinone +created_by: dph +creation_date: 2014-05-02T15:30:24Z + +[Term] +id: GO:1902959 +name: regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] +synonym: "regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0052548 ! regulation of endopeptidase activity +is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process +is_a: GO:1905245 ! regulation of aspartic-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +relationship: regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:07:04Z + +[Term] +id: GO:1902960 +name: negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] +synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartate protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartic-type endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of aspartyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of carboxyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0010951 ! negative regulation of endopeptidase activity +is_a: GO:1902959 ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +is_a: GO:1902992 ! negative regulation of amyloid precursor protein catabolic process +is_a: GO:1905246 ! negative regulation of aspartic-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +relationship: negatively_regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:07:11Z + +[Term] +id: GO:1902961 +name: positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] +synonym: "activation of aspartate protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of aspartate protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartate protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartate protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of aspartate protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartate protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartic-type endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of aspartyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of carboxyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0010950 ! positive regulation of endopeptidase activity +is_a: GO:1902959 ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +is_a: GO:1902993 ! positive regulation of amyloid precursor protein catabolic process +is_a: GO:1905247 ! positive regulation of aspartic-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +relationship: positively_regulates GO:1902944 ! aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:07:17Z + +[Term] +id: GO:1902962 +name: regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:18362153] +synonym: "regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process +is_a: GO:1904683 ! regulation of metalloendopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +relationship: regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:11:55Z + +[Term] +id: GO:1902963 +name: negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:18362153] +synonym: "down regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:1902962 ! regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +is_a: GO:1902992 ! negative regulation of amyloid precursor protein catabolic process +is_a: GO:1904684 ! negative regulation of metalloendopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +relationship: negatively_regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:12:01Z + +[Term] +id: GO:1902964 +name: positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:18362153] +synonym: "activation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of metalloendopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of metalloendopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity involved in APP catabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity involved in APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity involved in APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:1902962 ! regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process +is_a: GO:1902993 ! positive regulation of amyloid precursor protein catabolic process +is_a: GO:1904685 ! positive regulation of metalloendopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +relationship: positively_regulates GO:1902945 ! metalloendopeptidase activity involved in amyloid precursor protein catabolic process +created_by: sjp +creation_date: 2014-05-06T09:12:11Z + +[Term] +id: GO:1902965 +name: regulation of protein localization to early endosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to early endosome." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:22621900] +synonym: "regulation of protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in early endosome" EXACT [GOC:TermGenie] +is_a: GO:1905666 ! regulation of protein localization to endosome +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902946 ! protein localization to early endosome +relationship: regulates GO:1902946 ! protein localization to early endosome +created_by: sjp +creation_date: 2014-05-06T09:28:24Z + +[Term] +id: GO:1902966 +name: positive regulation of protein localization to early endosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to early endosome." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:22621900] +synonym: "activation of protein localisation in early endosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to early endosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in early endosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to early endosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in early endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in early endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to early endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in early endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to early endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in early endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to early endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in early endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to early endosome" EXACT [GOC:TermGenie] +is_a: GO:1902965 ! regulation of protein localization to early endosome +is_a: GO:1905668 ! positive regulation of protein localization to endosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902946 ! protein localization to early endosome +relationship: positively_regulates GO:1902946 ! protein localization to early endosome +created_by: sjp +creation_date: 2014-05-06T09:28:30Z + +[Term] +id: GO:1902967 +name: protein localization to mitotic spindle midzone +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone." [GO_REF:0000087, GOC:TermGenie, PMID:16824200] +synonym: "protein localisation in mitotic spindle midzone" EXACT [GOC:TermGenie] +synonym: "protein localisation to mitotic spindle midzone" EXACT [GOC:TermGenie] +synonym: "protein localization in mitotic spindle midzone" EXACT [GOC:TermGenie] +is_a: GO:1902480 ! protein localization to mitotic spindle +created_by: mah +creation_date: 2014-05-06T14:40:01Z + +[Term] +id: GO:1902969 +name: mitotic DNA replication +namespace: biological_process +def: "Any nuclear DNA replication that is involved in a mitotic cell cycle." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "mitotic cell cycle DNA replication" EXACT [] +synonym: "mitotic nuclear cell cycle DNA replication" EXACT [] +synonym: "nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [] +is_a: GO:0033260 ! nuclear DNA replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0033260 ! nuclear DNA replication +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2014-05-06T15:03:03Z + +[Term] +id: GO:1902970 +name: premeiotic DNA replication DNA duplex unwinding +namespace: biological_process +def: "Any DNA duplex unwinding involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA duplex unwinding involved in meiotic cell cycle DNA replication" EXACT [] +synonym: "DNA duplex unwinding involved in meiotic DNA replication" EXACT [] +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +is_a: GO:1902320 ! nuclear DNA replication DNA duplex unwinding +intersection_of: GO:1902320 ! nuclear DNA replication DNA duplex unwinding +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T15:20:41Z + +[Term] +id: GO:1902971 +name: mitotic DNA replication DNA duplex unwinding +namespace: biological_process +def: "Any DNA duplex unwinding involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA duplex unwinding involved in mitotic cell cycle DNA replication" EXACT [] +synonym: "DNA duplex unwinding involved in mitotic DNA replication" EXACT [] +is_a: GO:1902320 ! nuclear DNA replication DNA duplex unwinding +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902320 ! nuclear DNA replication DNA duplex unwinding +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T15:20:47Z + +[Term] +id: GO:1902972 +name: premeiotic DNA replication DNA ligation +namespace: biological_process +def: "Any DNA ligation involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA ligation involved in meiotic cell cycle DNA replication" RELATED [] +synonym: "DNA ligation involved in meiotic DNA replication" EXACT [] +is_a: GO:1902333 ! nuclear DNA replication DNA ligation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1902333 ! nuclear DNA replication DNA ligation +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T15:20:53Z + +[Term] +id: GO:1902973 +name: mitotic DNA replication DNA ligation +namespace: biological_process +def: "Any DNA ligation involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA ligation involved in mitotic cell cycle DNA replication" EXACT [] +synonym: "DNA ligation involved in mitotic DNA replication" EXACT [] +is_a: GO:1902333 ! nuclear DNA replication DNA ligation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902333 ! nuclear DNA replication DNA ligation +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T15:20:59Z + +[Term] +id: GO:1902974 +name: meiotic DNA replication initiation +namespace: biological_process +def: "Any DNA replication initiation involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication initiation involved in meiotic cell cycle DNA replication" EXACT [] +synonym: "DNA replication initiation involved in meiotic DNA replication" EXACT [] +is_a: GO:1902315 ! nuclear cell cycle DNA replication initiation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1902315 ! nuclear cell cycle DNA replication initiation +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2014-05-06T15:21:06Z + +[Term] +id: GO:1902975 +name: mitotic DNA replication initiation +namespace: biological_process +def: "Any DNA replication initiation involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [] +is_a: GO:1902315 ! nuclear cell cycle DNA replication initiation +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902315 ! nuclear cell cycle DNA replication initiation +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T15:21:11Z + +[Term] +id: GO:1902976 +name: premeiotic DNA replication preinitiation complex assembly +namespace: biological_process +def: "Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication preinitiation complex formation involved in meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "pre-IC complex assembly involved in meiotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0071163 ! DNA replication preinitiation complex assembly +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0071163 ! DNA replication preinitiation complex assembly +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:19:31Z + +[Term] +id: GO:1902977 +name: mitotic DNA replication preinitiation complex assembly +namespace: biological_process +def: "Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication preinitiation complex formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "pre-IC complex assembly involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0071163 ! DNA replication preinitiation complex assembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0071163 ! DNA replication preinitiation complex assembly +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:19:37Z + +[Term] +id: GO:1902978 +name: premeiotic DNA replication termination +namespace: biological_process +def: "Any DNA replication termination involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication termination involved in meiotic cell cycle DNA replication" EXACT [] +synonym: "DNA replication termination involved in meiotic DNA replication" EXACT [] +is_a: GO:1902317 ! nuclear DNA replication termination +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1902317 ! nuclear DNA replication termination +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:19:43Z + +[Term] +id: GO:1902979 +name: mitotic DNA replication termination +namespace: biological_process +def: "Any DNA replication termination involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA replication termination involved in mitotic cell cycle DNA replication" EXACT [] +is_a: GO:1902317 ! nuclear DNA replication termination +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902317 ! nuclear DNA replication termination +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:19:49Z + +[Term] +id: GO:1902980 +name: synthesis of RNA primer involved in premeiotic DNA replication +namespace: biological_process +def: "Any synthesis of RNA primer involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "synthesis of RNA primer involved in meiotic cell cycle DNA replication" EXACT [] +is_a: GO:1902318 ! synthesis of RNA primer involved in nuclear cell cycle DNA replication +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1902318 ! synthesis of RNA primer involved in nuclear cell cycle DNA replication +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:19:54Z + +[Term] +id: GO:1902981 +name: synthesis of RNA primer involved in mitotic DNA replication +namespace: biological_process +alt_id: GO:1903458 +def: "Any synthesis of RNA primer involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "synthesis of RNA primer involved in mitotic cell cycle DNA replication" EXACT [] +is_a: GO:1902318 ! synthesis of RNA primer involved in nuclear cell cycle DNA replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0006269 ! DNA replication, synthesis of RNA primer +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T19:20:00Z + +[Term] +id: GO:1902982 +name: DNA strand elongation involved in premeiotic DNA replication +namespace: biological_process +def: "Any DNA strand elongation involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA strand elongation involved in meiotic cell cycle DNA replication" EXACT [] +is_a: GO:1902319 ! DNA strand elongation involved in nuclear cell cycle DNA replication +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1902319 ! DNA strand elongation involved in nuclear cell cycle DNA replication +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T20:33:15Z + +[Term] +id: GO:1902983 +name: DNA strand elongation involved in mitotic DNA replication +namespace: biological_process +def: "Any DNA strand elongation involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "DNA strand elongation involved in mitotic cell cycle DNA replication" EXACT [] +is_a: GO:1902319 ! DNA strand elongation involved in nuclear cell cycle DNA replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902319 ! DNA strand elongation involved in nuclear cell cycle DNA replication +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T20:33:22Z + +[Term] +id: GO:1902984 +name: pre-replicative complex assembly involved in premeiotic DNA replication +namespace: biological_process +def: "Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "nuclear pre-replicative complex assembly involved in meiotic cell cycle" EXACT [GOC:TermGenie] +synonym: "pre-RC complex assembly involved in meiosis" BROAD [GOC:TermGenie] +synonym: "pre-replicative complex assembly involved in meiosis" BROAD [GOC:TermGenie] +synonym: "pre-replicative complex assembly involved in meiotic cell cycle DNA replication" EXACT [] +synonym: "pre-replicative complex formation involved in meiosis" BROAD [GOC:TermGenie] +is_a: GO:0006267 ! pre-replicative complex assembly involved in nuclear cell cycle DNA replication +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0006267 ! pre-replicative complex assembly involved in nuclear cell cycle DNA replication +intersection_of: part_of GO:0006279 ! premeiotic DNA replication +relationship: part_of GO:0006279 ! premeiotic DNA replication +created_by: jl +creation_date: 2014-05-06T20:33:28Z + +[Term] +id: GO:1902985 +name: mitotic pre-replicative complex assembly +namespace: biological_process +def: "Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:TermGenie] +synonym: "nuclear pre-replicative complex assembly involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "pre-replicative complex assembly involved in mitotic cell cycle DNA replication" EXACT [] +is_a: GO:0006267 ! pre-replicative complex assembly involved in nuclear cell cycle DNA replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0006267 ! pre-replicative complex assembly involved in nuclear cell cycle DNA replication +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: jl +creation_date: 2014-05-06T20:33:34Z + +[Term] +id: GO:1902986 +name: regulation of lysine biosynthetic process via aminoadipic acid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid." [GO_REF:0000058, GOC:TermGenie, PMID:8590464] +synonym: "regulation of lysine anabolism via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "regulation of lysine biosynthesis, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "regulation of lysine biosynthesis, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "regulation of lysine biosynthetic process, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "regulation of lysine biosynthetic process, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "regulation of lysine formation via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "regulation of lysine synthesis via aminoadipic acid" EXACT [GOC:TermGenie] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid +relationship: regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid +created_by: al +creation_date: 2014-05-07T08:07:08Z + +[Term] +id: GO:1902987 +name: negative regulation of lysine biosynthetic process via aminoadipic acid +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid." [GO_REF:0000058, GOC:TermGenie, PMID:8590464] +synonym: "down regulation of lysine anabolism via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine biosynthesis, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine biosynthesis, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine biosynthetic process via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine biosynthetic process, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine biosynthetic process, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine formation via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down regulation of lysine synthesis via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine anabolism via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine biosynthesis, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine biosynthesis, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine biosynthetic process via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine biosynthetic process, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine biosynthetic process, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine formation via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysine synthesis via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine anabolism via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine biosynthesis, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine biosynthesis, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine biosynthetic process via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine biosynthetic process, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine biosynthetic process, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine formation via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of lysine synthesis via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "inhibition of lysine anabolism via aminoadipic acid" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine biosynthesis, aminoadipic acid pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine biosynthesis, aminoadipic pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine biosynthetic process via aminoadipic acid" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine biosynthetic process, aminoadipic acid pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine biosynthetic process, aminoadipic pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine formation via aminoadipic acid" NARROW [GOC:TermGenie] +synonym: "inhibition of lysine synthesis via aminoadipic acid" NARROW [GOC:TermGenie] +synonym: "negative regulation of lysine anabolism via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine biosynthesis, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine biosynthesis, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine biosynthetic process, aminoadipic acid pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine biosynthetic process, aminoadipic pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine formation via aminoadipic acid" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysine synthesis via aminoadipic acid" EXACT [GOC:TermGenie] +is_a: GO:1902986 ! regulation of lysine biosynthetic process via aminoadipic acid +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid +relationship: negatively_regulates GO:0019878 ! lysine biosynthetic process via aminoadipic acid +created_by: al +creation_date: 2014-05-07T08:07:15Z + +[Term] +id: GO:1902988 +name: neurofibrillary tangle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle." [GO_REF:0000079, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780, PMID:24154541] +comment: Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267). +synonym: "flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +is_a: GO:0070841 ! inclusion body assembly +created_by: sjp +creation_date: 2014-05-08T09:19:51Z + +[Term] +id: GO:1902989 +name: meiotic telomere maintenance via semi-conservative replication +namespace: biological_process +def: "Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle." [GO_REF:0000060, GOC:TermGenie] +synonym: "equal telomere replication involved in meiotic cell cycle" RELATED [GOC:TermGenie] +synonym: "telomeric fork progression involved in meiotic cell cycle" NARROW [GOC:TermGenie] +synonym: "telomeric replication fork progression involved in meiotic cell cycle" NARROW [GOC:TermGenie] +is_a: GO:0032201 ! telomere maintenance via semi-conservative replication +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +intersection_of: GO:0032201 ! telomere maintenance via semi-conservative replication +intersection_of: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2014-05-08T11:13:43Z + +[Term] +id: GO:1902990 +name: mitotic telomere maintenance via semi-conservative replication +namespace: biological_process +def: "Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle." [GO_REF:0000060, GOC:TermGenie] +synonym: "equal telomere replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "telomeric fork progression involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "telomeric replication fork progression involved in mitotic cell cycle" NARROW [GOC:TermGenie] +is_a: GO:0032201 ! telomere maintenance via semi-conservative replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0032201 ! telomere maintenance via semi-conservative replication +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2014-05-08T11:13:49Z + +[Term] +id: GO:1902991 +name: regulation of amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:24499793] +comment: An example of this is human FKBP1A/12 (UniProt symbol P62942) in PMID:24499793 (inferred from direct assay). +synonym: "regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042987 ! amyloid precursor protein catabolic process +relationship: regulates GO:0042987 ! amyloid precursor protein catabolic process +created_by: rl +creation_date: 2014-05-08T14:21:04Z + +[Term] +id: GO:1902992 +name: negative regulation of amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:24499793] +synonym: "down regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of APP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of APP catabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042987 ! amyloid precursor protein catabolic process +relationship: negatively_regulates GO:0042987 ! amyloid precursor protein catabolic process +created_by: rl +creation_date: 2014-05-08T14:21:10Z + +[Term] +id: GO:1902993 +name: positive regulation of amyloid precursor protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:24499793] +synonym: "activation of amyloid precursor protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of amyloid precursor protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of amyloid precursor protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of APP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of APP catabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of APP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of amyloid precursor protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of amyloid precursor protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of amyloid precursor protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of APP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of APP catabolism" EXACT [GOC:TermGenie] +is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:1902991 ! regulation of amyloid precursor protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042987 ! amyloid precursor protein catabolic process +relationship: positively_regulates GO:0042987 ! amyloid precursor protein catabolic process +created_by: rl +creation_date: 2014-05-08T14:21:16Z + +[Term] +id: GO:1902994 +name: regulation of phospholipid efflux +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipid efflux." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:12042316] +synonym: "regulation of phospholipid export" EXACT [GOC:TermGenie] +is_a: GO:2001138 ! regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033700 ! phospholipid efflux +relationship: regulates GO:0033700 ! phospholipid efflux +created_by: sjp +creation_date: 2014-05-08T14:55:16Z + +[Term] +id: GO:1902995 +name: positive regulation of phospholipid efflux +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipid efflux." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:12042316] +synonym: "activation of phospholipid efflux" NARROW [GOC:TermGenie] +synonym: "activation of phospholipid export" NARROW [GOC:TermGenie] +synonym: "positive regulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipid export" EXACT [GOC:TermGenie] +is_a: GO:1902994 ! regulation of phospholipid efflux +is_a: GO:2001140 ! positive regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033700 ! phospholipid efflux +relationship: positively_regulates GO:0033700 ! phospholipid efflux +created_by: sjp +creation_date: 2014-05-08T14:55:22Z + +[Term] +id: GO:1902996 +name: regulation of neurofibrillary tangle assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:15897157] +synonym: "regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +is_a: GO:0090083 ! regulation of inclusion body assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902988 ! neurofibrillary tangle assembly +relationship: regulates GO:1902988 ! neurofibrillary tangle assembly +created_by: sjp +creation_date: 2014-05-08T15:44:27Z + +[Term] +id: GO:1902997 +name: negative regulation of neurofibrillary tangle assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:15897157] +synonym: "down regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "down regulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "down regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "downregulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "downregulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "inhibition of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "inhibition of neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "inhibition of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +is_a: GO:0090084 ! negative regulation of inclusion body assembly +is_a: GO:1902996 ! regulation of neurofibrillary tangle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902988 ! neurofibrillary tangle assembly +relationship: negatively_regulates GO:1902988 ! neurofibrillary tangle assembly +created_by: sjp +creation_date: 2014-05-08T15:44:33Z + +[Term] +id: GO:1902998 +name: positive regulation of neurofibrillary tangle assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:15897157] +synonym: "activation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "activation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "activation of neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "activation of neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "activation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "activation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "up regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "up regulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "upregulation of flame-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of flame-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +synonym: "upregulation of neurofibrillary tangle assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of neurofibrillary tangle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of star-shaped neurofibrillary tangle assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of star-shaped neurofibrillary tangle formation" NARROW [GOC:TermGenie] +is_a: GO:0090261 ! positive regulation of inclusion body assembly +is_a: GO:1902996 ! regulation of neurofibrillary tangle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902988 ! neurofibrillary tangle assembly +relationship: positively_regulates GO:1902988 ! neurofibrillary tangle assembly +created_by: sjp +creation_date: 2014-05-08T15:44:45Z + +[Term] +id: GO:1902999 +name: negative regulation of phospholipid efflux +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:12042316] +synonym: "down regulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "down regulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipid efflux" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipid export" EXACT [GOC:TermGenie] +synonym: "inhibition of phospholipid efflux" NARROW [GOC:TermGenie] +synonym: "inhibition of phospholipid export" NARROW [GOC:TermGenie] +synonym: "negative regulation of phospholipid export" EXACT [GOC:TermGenie] +is_a: GO:1902994 ! regulation of phospholipid efflux +is_a: GO:2001139 ! negative regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033700 ! phospholipid efflux +relationship: negatively_regulates GO:0033700 ! phospholipid efflux +created_by: sjp +creation_date: 2014-05-09T08:09:59Z + +[Term] +id: GO:1903000 +name: regulation of lipid transport across blood-brain barrier +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24345162] +synonym: "regulation of lipid transport across blood brain barrier" EXACT [] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0150200 ! regulation of transport across blood-brain barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990379 ! lipid transport across blood-brain barrier +relationship: regulates GO:1990379 ! lipid transport across blood-brain barrier +created_by: sjp +creation_date: 2014-05-09T09:30:04Z + +[Term] +id: GO:1903001 +name: negative regulation of lipid transport across blood-brain barrier +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24345162] +synonym: "down regulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +synonym: "downregulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +synonym: "inhibition of lipid transport across blood brain barrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of lipid transport across blood brain barrier" EXACT [] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0150202 ! negative regulation of transport across blood-brain barrier +is_a: GO:1903000 ! regulation of lipid transport across blood-brain barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990379 ! lipid transport across blood-brain barrier +relationship: negatively_regulates GO:1990379 ! lipid transport across blood-brain barrier +created_by: sjp +creation_date: 2014-05-09T09:30:10Z + +[Term] +id: GO:1903002 +name: positive regulation of lipid transport across blood-brain barrier +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier." [GO_REF:0000058, GOC:sjp, GOC:TermGenie, PMID:24345162] +synonym: "activation of lipid transport across blood brain barrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of lipid transport across blood brain barrier" EXACT [] +synonym: "up regulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +synonym: "upregulation of lipid transport across blood brain barrier" EXACT [GOC:TermGenie] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0150201 ! positive regulation of transport across blood-brain barrier +is_a: GO:1903000 ! regulation of lipid transport across blood-brain barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990379 ! lipid transport across blood-brain barrier +relationship: positively_regulates GO:1990379 ! lipid transport across blood-brain barrier +created_by: sjp +creation_date: 2014-05-09T09:30:16Z + +[Term] +id: GO:1903003 +name: positive regulation of protein deubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] +synonym: "activation of deubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein deubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of protein deubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of protein deubiquitylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of deubiquitination" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein deubiquitylation" EXACT [GOC:TermGenie] +synonym: "up regulation of deubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein deubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of protein deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein deubiquitylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of deubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein deubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein deubiquitylation" EXACT [GOC:TermGenie] +synonym: "upregulation of deubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein deubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein deubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:0090085 ! regulation of protein deubiquitination +is_a: GO:1903322 ! positive regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016579 ! protein deubiquitination +relationship: positively_regulates GO:0016579 ! protein deubiquitination +created_by: bf +creation_date: 2014-05-12T15:39:10Z + +[Term] +id: GO:1903004 +name: regulation of protein K63-linked deubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] +is_a: GO:0090085 ! regulation of protein deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070536 ! protein K63-linked deubiquitination +relationship: regulates GO:0070536 ! protein K63-linked deubiquitination +created_by: bf +creation_date: 2014-05-12T15:40:43Z + +[Term] +id: GO:1903005 +name: negative regulation of protein K63-linked deubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] +synonym: "down regulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "inhibition of protein K63-linked deubiquitination" NARROW [GOC:TermGenie] +is_a: GO:0090086 ! negative regulation of protein deubiquitination +is_a: GO:1903004 ! regulation of protein K63-linked deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070536 ! protein K63-linked deubiquitination +relationship: negatively_regulates GO:0070536 ! protein K63-linked deubiquitination +created_by: bf +creation_date: 2014-05-12T15:40:49Z + +[Term] +id: GO:1903006 +name: positive regulation of protein K63-linked deubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] +synonym: "activation of protein K63-linked deubiquitination" NARROW [GOC:TermGenie] +synonym: "up regulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of protein K63-linked deubiquitination" EXACT [GOC:TermGenie] +is_a: GO:1903003 ! positive regulation of protein deubiquitination +is_a: GO:1903004 ! regulation of protein K63-linked deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070536 ! protein K63-linked deubiquitination +relationship: positively_regulates GO:0070536 ! protein K63-linked deubiquitination +created_by: bf +creation_date: 2014-05-12T15:40:55Z + +[Term] +id: GO:1903007 +name: positive regulation of Lys63-specific deubiquitinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] +synonym: "activation of Lys63-specific deubiquitinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903006 ! positive regulation of protein K63-linked deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061578 ! Lys63-specific deubiquitinase activity +relationship: positively_regulates GO:0061578 ! Lys63-specific deubiquitinase activity +created_by: bf +creation_date: 2014-05-12T15:47:35Z + +[Term] +id: GO:1903008 +name: organelle disassembly +namespace: biological_process +def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie] +synonym: "organelle degradation" EXACT [] +is_a: GO:0006996 ! organelle organization +is_a: GO:0022411 ! cellular component disassembly +created_by: jl +creation_date: 2014-05-13T12:36:03Z + +[Term] +id: GO:1903009 +name: proteasome complex disassembly +namespace: biological_process +def: "The disaggregation of a proteasome complex into its constituent components." [GO_REF:0000079, GOC:TermGenie] +synonym: "26S proteasome disassembly" NARROW [GOC:TermGenie] +synonym: "proteasome degradation" EXACT [] +synonym: "proteasome disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: jl +creation_date: 2014-05-13T12:41:59Z + +[Term] +id: GO:1903010 +name: regulation of bone development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060348 ! bone development +relationship: regulates GO:0060348 ! bone development +created_by: mr +creation_date: 2014-05-13T22:41:53Z + +[Term] +id: GO:1903011 +name: negative regulation of bone development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] +synonym: "down regulation of bone development" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone development" EXACT [GOC:TermGenie] +synonym: "downregulation of bone development" EXACT [GOC:TermGenie] +synonym: "inhibition of bone development" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903010 ! regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060348 ! bone development +relationship: negatively_regulates GO:0060348 ! bone development +created_by: mr +creation_date: 2014-05-13T22:42:00Z + +[Term] +id: GO:1903012 +name: positive regulation of bone development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] +synonym: "activation of bone development" NARROW [GOC:TermGenie] +synonym: "up regulation of bone development" EXACT [GOC:TermGenie] +synonym: "up-regulation of bone development" EXACT [GOC:TermGenie] +synonym: "upregulation of bone development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903010 ! regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060348 ! bone development +relationship: positively_regulates GO:0060348 ! bone development +created_by: mr +creation_date: 2014-05-13T22:42:06Z + +[Term] +id: GO:1903013 +name: response to differentiation-inducing factor 1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365144] +synonym: "DIF-1" RELATED [] +synonym: "response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one" EXACT [] +synonym: "response to DIF-1" RELATED [] +synonym: "response to DIF1" RELATED [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:1901654 ! response to ketone +created_by: rjd +creation_date: 2014-05-14T16:18:11Z + +[Term] +id: GO:1903014 +name: cellular response to differentiation-inducing factor 1 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365144] +synonym: "cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one" EXACT [] +synonym: "cellular response to DIF-1" RELATED [] +synonym: "cellular response to DIF1" RELATED [] +synonym: "DIF-1" RELATED [] +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1903013 ! response to differentiation-inducing factor 1 +created_by: rjd +creation_date: 2014-05-14T16:18:18Z + +[Term] +id: GO:1903015 +name: regulation of exo-alpha-sialidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA) +synonym: "regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of sialidase activity" EXACT [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004308 ! exo-alpha-sialidase activity +relationship: regulates GO:0004308 ! exo-alpha-sialidase activity +created_by: rl +creation_date: 2014-05-14T18:15:11Z + +[Term] +id: GO:1903016 +name: negative regulation of exo-alpha-sialidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA) +synonym: "down regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of acetylneuraminidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of acetylneuraminyl hydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of alpha-neuraminidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of exo-alpha-sialidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of N-acylneuraminate glycohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of neuraminidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sialidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of sialidase activity" EXACT [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:1903015 ! regulation of exo-alpha-sialidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004308 ! exo-alpha-sialidase activity +relationship: negatively_regulates GO:0004308 ! exo-alpha-sialidase activity +created_by: rl +creation_date: 2014-05-14T18:15:17Z + +[Term] +id: GO:1903017 +name: positive regulation of exo-alpha-sialidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA) +synonym: "activation of acetylneuraminidase activity" NARROW [GOC:TermGenie] +synonym: "activation of acetylneuraminyl hydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of alpha-neuraminidase activity" NARROW [GOC:TermGenie] +synonym: "activation of exo-alpha-sialidase activity" NARROW [GOC:TermGenie] +synonym: "activation of N-acylneuraminate glycohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of neuraminidase activity" NARROW [GOC:TermGenie] +synonym: "activation of sialidase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of sialidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of neuraminidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of sialidase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903015 ! regulation of exo-alpha-sialidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004308 ! exo-alpha-sialidase activity +relationship: positively_regulates GO:0004308 ! exo-alpha-sialidase activity +created_by: rl +creation_date: 2014-05-14T18:15:23Z + +[Term] +id: GO:1903018 +name: regulation of glycoprotein metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein +synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009100 ! glycoprotein metabolic process +relationship: regulates GO:0009100 ! glycoprotein metabolic process +created_by: rl +creation_date: 2014-05-14T18:44:19Z + +[Term] +id: GO:1903019 +name: negative regulation of glycoprotein metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein +synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:1903018 ! regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process +relationship: negatively_regulates GO:0009100 ! glycoprotein metabolic process +created_by: rl +creation_date: 2014-05-14T18:44:25Z + +[Term] +id: GO:1903020 +name: positive regulation of glycoprotein metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] +comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein +synonym: "activation of glycoprotein metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of glycoprotein metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:1903018 ! regulation of glycoprotein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009100 ! glycoprotein metabolic process +relationship: positively_regulates GO:0009100 ! glycoprotein metabolic process +created_by: rl +creation_date: 2014-05-14T18:44:31Z + +[Term] +id: GO:1903021 +name: regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands." [GO_REF:0000059, GOC:rb, GOC:TermGenie, PMID:12192046] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090580 ! phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +relationship: regulates GO:0090580 ! phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +created_by: tb +creation_date: 2014-05-14T23:44:35Z + +[Term] +id: GO:1903022 +name: positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands." [GO_REF:0000059, GOC:rb, GOC:TermGenie, PMID:12192046] +synonym: "activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands" NARROW [GOC:TermGenie] +synonym: "up regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903021 ! regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090580 ! phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +relationship: positively_regulates GO:0090580 ! phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands +created_by: tb +creation_date: 2014-05-14T23:44:47Z + +[Term] +id: GO:1903023 +name: regulation of ascospore-type prospore membrane formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane." [GO_REF:0000058, GOC:TermGenie, PMID:11405625] +synonym: "regulation of ascospore-type prospore membrane assembly" RELATED [] +synonym: "regulation of forespore membrane biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of forespore membrane formation" EXACT [GOC:TermGenie] +synonym: "regulation of FSM assembly" EXACT [GOC:TermGenie] +synonym: "regulation of FSM biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of FSM formation" EXACT [GOC:TermGenie] +is_a: GO:0034307 ! regulation of ascospore formation +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032120 ! ascospore-type prospore membrane formation +relationship: regulates GO:0032120 ! ascospore-type prospore membrane formation +created_by: al +creation_date: 2014-05-15T08:51:51Z + +[Term] +id: GO:1903024 +name: positive regulation of ascospore-type prospore membrane formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane." [GO_REF:0000058, GOC:TermGenie, PMID:11405625] +synonym: "activation of ascospore-type prospore membrane assembly" NARROW [GOC:TermGenie] +synonym: "activation of forespore membrane biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of forespore membrane formation" NARROW [GOC:TermGenie] +synonym: "activation of FSM assembly" NARROW [GOC:TermGenie] +synonym: "activation of FSM biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of FSM formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ascospore-type prospore membrane assembly" RELATED [] +synonym: "positive regulation of forespore membrane biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of forespore membrane formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of FSM assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of FSM biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of FSM formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ascospore-type prospore membrane assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of forespore membrane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of forespore membrane formation" EXACT [GOC:TermGenie] +synonym: "up regulation of FSM assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of FSM biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of FSM formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ascospore-type prospore membrane assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of forespore membrane biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of forespore membrane formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of FSM assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of FSM biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of FSM formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ascospore-type prospore membrane assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of forespore membrane biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of forespore membrane formation" EXACT [GOC:TermGenie] +synonym: "upregulation of FSM assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of FSM biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of FSM formation" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0075296 ! positive regulation of ascospore formation +is_a: GO:1903023 ! regulation of ascospore-type prospore membrane formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032120 ! ascospore-type prospore membrane formation +relationship: positively_regulates GO:0032120 ! ascospore-type prospore membrane formation +created_by: al +creation_date: 2014-05-15T08:51:58Z + +[Term] +id: GO:1903025 +name: regulation of RNA polymerase II regulatory region sequence-specific DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding." [GO_REF:0000059, GOC:dph, GOC:krc, GOC:TermGenie, PMID:20026326] +is_a: GO:2000677 ! regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +relationship: regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +created_by: dph +creation_date: 2014-05-15T17:55:54Z + +[Term] +id: GO:1903026 +name: negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding." [GO_REF:0000059, GOC:dph, GOC:krc, GOC:TermGenie, PMID:20026326] +synonym: "down regulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA polymerase II regulatory region sequence-specific DNA binding" NARROW [GOC:TermGenie] +is_a: GO:1903025 ! regulation of RNA polymerase II regulatory region sequence-specific DNA binding +is_a: GO:2000678 ! negative regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +relationship: negatively_regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +created_by: dph +creation_date: 2014-05-15T17:56:00Z + +[Term] +id: GO:1903027 +name: regulation of opsonization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of opsonization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22333221] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0050764 ! regulation of phagocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008228 ! opsonization +relationship: regulates GO:0008228 ! opsonization +created_by: rl +creation_date: 2014-05-16T17:34:41Z + +[Term] +id: GO:1903028 +name: positive regulation of opsonization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of opsonization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22333221] +synonym: "activation of opsonization" NARROW [GOC:TermGenie] +synonym: "up regulation of opsonization" EXACT [GOC:TermGenie] +synonym: "up-regulation of opsonization" EXACT [GOC:TermGenie] +synonym: "upregulation of opsonization" EXACT [GOC:TermGenie] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0050766 ! positive regulation of phagocytosis +is_a: GO:1903027 ! regulation of opsonization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008228 ! opsonization +relationship: positively_regulates GO:0008228 ! opsonization +created_by: rl +creation_date: 2014-05-16T17:34:54Z + +[Term] +id: GO:1903031 +name: regulation of microtubule plus-end binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule plus-end binding." [GO_REF:0000059, GOC:hjd, GOC:TermGenie, PMID:16148041] +is_a: GO:1904526 ! regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051010 ! microtubule plus-end binding +relationship: regulates GO:0051010 ! microtubule plus-end binding +created_by: hjd +creation_date: 2014-05-16T18:38:26Z + +[Term] +id: GO:1903032 +name: negative regulation of microtubule plus-end binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding." [GO_REF:0000059, GOC:hjd, GOC:TermGenie, PMID:16148041] +synonym: "down regulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +synonym: "inhibition of microtubule plus-end binding" NARROW [GOC:TermGenie] +is_a: GO:1903031 ! regulation of microtubule plus-end binding +is_a: GO:1904527 ! negative regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051010 ! microtubule plus-end binding +relationship: negatively_regulates GO:0051010 ! microtubule plus-end binding +created_by: hjd +creation_date: 2014-05-16T18:38:32Z + +[Term] +id: GO:1903033 +name: positive regulation of microtubule plus-end binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding." [GO_REF:0000059, GOC:hjd, GOC:TermGenie, PMID:16148041] +synonym: "activation of microtubule plus-end binding" NARROW [GOC:TermGenie] +synonym: "up regulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule plus-end binding" EXACT [GOC:TermGenie] +is_a: GO:1903031 ! regulation of microtubule plus-end binding +is_a: GO:1904528 ! positive regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051010 ! microtubule plus-end binding +relationship: positively_regulates GO:0051010 ! microtubule plus-end binding +created_by: hjd +creation_date: 2014-05-16T18:38:38Z + +[Term] +id: GO:1903034 +name: regulation of response to wounding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535] +synonym: "regulation of physiological response to wounding" EXACT [GOC:TermGenie] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009611 ! response to wounding +relationship: regulates GO:0009611 ! response to wounding +created_by: kmv +creation_date: 2014-05-18T01:28:46Z + +[Term] +id: GO:1903035 +name: negative regulation of response to wounding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535] +synonym: "down regulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "down regulation of response to wounding" EXACT [GOC:TermGenie] +synonym: "down-regulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to wounding" EXACT [GOC:TermGenie] +synonym: "downregulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "downregulation of response to wounding" EXACT [GOC:TermGenie] +synonym: "inhibition of physiological response to wounding" NARROW [GOC:TermGenie] +synonym: "inhibition of response to wounding" NARROW [GOC:TermGenie] +synonym: "negative regulation of physiological response to wounding" EXACT [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1903034 ! regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009611 ! response to wounding +relationship: negatively_regulates GO:0009611 ! response to wounding +created_by: kmv +creation_date: 2014-05-18T01:28:52Z + +[Term] +id: GO:1903036 +name: positive regulation of response to wounding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to wounding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:19164535] +synonym: "activation of physiological response to wounding" NARROW [GOC:TermGenie] +synonym: "activation of response to wounding" NARROW [GOC:TermGenie] +synonym: "positive regulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "up regulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "up regulation of response to wounding" EXACT [GOC:TermGenie] +synonym: "up-regulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to wounding" EXACT [GOC:TermGenie] +synonym: "upregulation of physiological response to wounding" EXACT [GOC:TermGenie] +synonym: "upregulation of response to wounding" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1903034 ! regulation of response to wounding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009611 ! response to wounding +relationship: positively_regulates GO:0009611 ! response to wounding +created_by: kmv +creation_date: 2014-05-18T01:28:58Z + +[Term] +id: GO:1903037 +name: regulation of leukocyte cell-cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] +comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion +synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007159 ! leukocyte cell-cell adhesion +relationship: regulates GO:0007159 ! leukocyte cell-cell adhesion +created_by: rl +creation_date: 2014-05-19T15:29:58Z + +[Term] +id: GO:1903038 +name: negative regulation of leukocyte cell-cell adhesion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] +comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion +synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +synonym: "inhibition of leukocyte adhesion" NARROW [GOC:TermGenie] +synonym: "inhibition of leukocyte cell adhesion" NARROW [GOC:TermGenie] +synonym: "inhibition of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] +synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion +relationship: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion +created_by: rl +creation_date: 2014-05-19T15:30:05Z + +[Term] +id: GO:1903039 +name: positive regulation of leukocyte cell-cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] +comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion +synonym: "activation of leukocyte adhesion" NARROW [GOC:TermGenie] +synonym: "activation of leukocyte cell adhesion" NARROW [GOC:TermGenie] +synonym: "activation of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] +synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion +relationship: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion +created_by: rl +creation_date: 2014-05-19T15:30:15Z + +[Term] +id: GO:1903040 +name: exon-exon junction complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex." [GO_REF:0000079, GOC:sart, GOC:TermGenie, PMID:17606899] +synonym: "EJC assembly" EXACT [GOC:TermGenie] +synonym: "EJC formation" EXACT [GOC:TermGenie] +synonym: "exon-exon junction complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: sart +creation_date: 2014-05-20T14:52:07Z + +[Term] +id: GO:1903041 +name: regulation of chondrocyte hypertrophy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:23928032] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0061181 ! regulation of chondrocyte development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003415 ! chondrocyte hypertrophy +relationship: regulates GO:0003415 ! chondrocyte hypertrophy +created_by: mr +creation_date: 2014-05-20T21:23:13Z + +[Term] +id: GO:1903042 +name: negative regulation of chondrocyte hypertrophy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:23928032] +synonym: "down regulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +synonym: "down-regulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +synonym: "downregulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +synonym: "inhibition of chondrocyte hypertrophy" NARROW [GOC:TermGenie] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0061182 ! negative regulation of chondrocyte development +is_a: GO:1903041 ! regulation of chondrocyte hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003415 ! chondrocyte hypertrophy +relationship: negatively_regulates GO:0003415 ! chondrocyte hypertrophy +created_by: mr +creation_date: 2014-05-20T21:23:19Z + +[Term] +id: GO:1903043 +name: positive regulation of chondrocyte hypertrophy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:23928032] +synonym: "activation of chondrocyte hypertrophy" NARROW [GOC:TermGenie] +synonym: "up regulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +synonym: "up-regulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +synonym: "upregulation of chondrocyte hypertrophy" EXACT [GOC:TermGenie] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1902761 ! positive regulation of chondrocyte development +is_a: GO:1903041 ! regulation of chondrocyte hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003415 ! chondrocyte hypertrophy +relationship: positively_regulates GO:0003415 ! chondrocyte hypertrophy +created_by: mr +creation_date: 2014-05-20T21:23:25Z + +[Term] +id: GO:1903044 +name: protein localization to membrane raft +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a membrane raft." [GO_REF:0000087, GOC:dl, GOC:TermGenie, PMID:19414744] +synonym: "protein localisation in membrane raft" EXACT [GOC:TermGenie] +synonym: "protein localisation to membrane raft" EXACT [GOC:TermGenie] +synonym: "protein localization in membrane raft" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +created_by: dl +creation_date: 2014-05-21T10:49:03Z + +[Term] +id: GO:1903045 +name: neural crest cell migration involved in sympathetic nervous system development +namespace: biological_process +def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129] +comment: Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development +is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development +intersection_of: GO:0001755 ! neural crest cell migration +intersection_of: part_of GO:0048485 ! sympathetic nervous system development +relationship: part_of GO:0048485 ! sympathetic nervous system development +created_by: rl +creation_date: 2014-05-22T07:06:02Z + +[Term] +id: GO:1903046 +name: meiotic cell cycle process +namespace: biological_process +def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +subset: gocheck_do_not_annotate +subset: goslim_pombe +is_a: GO:0022402 ! cell cycle process +is_a: GO:0022414 ! reproductive process +intersection_of: GO:0009987 ! cellular process +intersection_of: part_of GO:0051321 ! meiotic cell cycle +disjoint_from: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0051321 ! meiotic cell cycle +created_by: jl +creation_date: 2014-05-22T14:22:28Z + +[Term] +id: GO:1903047 +name: mitotic cell cycle process +namespace: biological_process +def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +subset: gocheck_do_not_annotate +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0009987 ! cellular process +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2014-05-22T14:22:34Z + +[Term] +id: GO:1903048 +name: regulation of acetylcholine-gated cation channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21718690] +is_a: GO:0098815 ! modulation of excitatory postsynaptic potential +is_a: GO:0098962 ! regulation of postsynaptic neurotransmitter receptor activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022848 ! acetylcholine-gated cation-selective channel activity +relationship: regulates GO:0022848 ! acetylcholine-gated cation-selective channel activity +created_by: bf +creation_date: 2014-05-22T14:46:53Z + +[Term] +id: GO:1903049 +name: negative regulation of acetylcholine-gated cation channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21718690] +synonym: "down regulation of acetylcholine-gated cation channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine-gated cation channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine-gated cation channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of acetylcholine-gated cation channel activity" NARROW [GOC:TermGenie] +is_a: GO:0090394 ! negative regulation of excitatory postsynaptic potential +is_a: GO:1903048 ! regulation of acetylcholine-gated cation channel activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022848 ! acetylcholine-gated cation-selective channel activity +relationship: negatively_regulates GO:0022848 ! acetylcholine-gated cation-selective channel activity +created_by: bf +creation_date: 2014-05-22T14:47:00Z + +[Term] +id: GO:1903050 +name: regulation of proteolysis involved in cellular protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834] +comment: overexpression of cathepsin C propeptide significantly increased the degradation of of intestinal alkaline phosphatase (IAP) +synonym: "regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +is_a: GO:0030162 ! regulation of proteolysis +is_a: GO:1903362 ! regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +relationship: regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +created_by: rl +creation_date: 2014-05-22T18:00:45Z + +[Term] +id: GO:1903051 +name: negative regulation of proteolysis involved in cellular protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834] +comment: Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP). +synonym: "down regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "downregulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "downregulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "inhibition of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of peptidolysis involved in cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidolysis involved in cellular protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "inhibition of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of proteolysis involved in cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +is_a: GO:0045861 ! negative regulation of proteolysis +is_a: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process +is_a: GO:1903363 ! negative regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +relationship: negatively_regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +created_by: rl +creation_date: 2014-05-22T18:00:51Z + +[Term] +id: GO:1903052 +name: positive regulation of proteolysis involved in cellular protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834] +comment: overexpression of cathepsin C propeptide significantly increased the degradation of of intestinal alkaline phosphatase (IAP) +synonym: "activation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "activation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "activation of peptidolysis involved in cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of peptidolysis involved in cellular protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "activation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "activation of proteolysis involved in cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of peptidolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of peptidolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidolysis involved in cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of proteolysis during cellular protein catabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of proteolysis during cellular protein catabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of proteolysis involved in cellular protein catabolic process" EXACT [GOC:TermGenie] +is_a: GO:0045862 ! positive regulation of proteolysis +is_a: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process +is_a: GO:1903364 ! positive regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +relationship: positively_regulates GO:0051603 ! proteolysis involved in cellular protein catabolic process +created_by: rl +creation_date: 2014-05-22T18:00:57Z + +[Term] +id: GO:1903053 +name: regulation of extracellular matrix organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] +synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030198 ! extracellular matrix organization +relationship: regulates GO:0030198 ! extracellular matrix organization +created_by: rl +creation_date: 2014-05-23T17:15:41Z + +[Term] +id: GO:1903054 +name: negative regulation of extracellular matrix organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] +synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "down regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of extracellular matrix organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of extracellular matrix organization" NARROW [GOC:TermGenie] +synonym: "inhibition of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030198 ! extracellular matrix organization +relationship: negatively_regulates GO:0030198 ! extracellular matrix organization +created_by: rl +creation_date: 2014-05-23T17:15:47Z + +[Term] +id: GO:1903055 +name: positive regulation of extracellular matrix organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] +synonym: "activation of extracellular matrix organisation" NARROW [GOC:TermGenie] +synonym: "activation of extracellular matrix organization" NARROW [GOC:TermGenie] +synonym: "activation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "up regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030198 ! extracellular matrix organization +relationship: positively_regulates GO:0030198 ! extracellular matrix organization +created_by: rl +creation_date: 2014-05-23T17:15:53Z + +[Term] +id: GO:1903056 +name: regulation of melanosome organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of melanosome organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24769727] +comment: Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles +synonym: "regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032438 ! melanosome organization +relationship: regulates GO:0032438 ! melanosome organization +created_by: rl +creation_date: 2014-05-27T13:27:49Z + +[Term] +id: GO:1903057 +name: negative regulation of melanosome organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24769727] +comment: Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles. +synonym: "down regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "down regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "downregulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of melanosome organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of melanosome organization" NARROW [GOC:TermGenie] +synonym: "inhibition of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1903056 ! regulation of melanosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032438 ! melanosome organization +relationship: negatively_regulates GO:0032438 ! melanosome organization +created_by: rl +creation_date: 2014-05-27T13:27:55Z + +[Term] +id: GO:1903058 +name: positive regulation of melanosome organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of melanosome organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24769727] +comment: Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles. +synonym: "activation of melanosome organisation" NARROW [GOC:TermGenie] +synonym: "activation of melanosome organization" NARROW [GOC:TermGenie] +synonym: "activation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "up regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of melanosome organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of melanosome organization" EXACT [GOC:TermGenie] +synonym: "upregulation of melanosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1903056 ! regulation of melanosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032438 ! melanosome organization +relationship: positively_regulates GO:0032438 ! melanosome organization +created_by: rl +creation_date: 2014-05-27T13:28:01Z + +[Term] +id: GO:1903059 +name: regulation of protein lipidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] +synonym: "regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:0050746 ! regulation of lipoprotein metabolic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006497 ! protein lipidation +relationship: regulates GO:0006497 ! protein lipidation +created_by: rph +creation_date: 2014-05-28T13:21:18Z + +[Term] +id: GO:1903060 +name: negative regulation of protein lipidation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] +synonym: "down regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "down regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein lipidation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein lipidation" EXACT [GOC:TermGenie] +synonym: "downregulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "downregulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein lipidation" EXACT [GOC:TermGenie] +synonym: "inhibition of lipid:protein modification" NARROW [GOC:TermGenie] +synonym: "inhibition of protein amino acid lipidation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein lipidation" NARROW [GOC:TermGenie] +synonym: "negative regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0050748 ! negative regulation of lipoprotein metabolic process +is_a: GO:1903059 ! regulation of protein lipidation +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006497 ! protein lipidation +relationship: negatively_regulates GO:0006497 ! protein lipidation +created_by: rph +creation_date: 2014-05-28T13:21:25Z + +[Term] +id: GO:1903061 +name: positive regulation of protein lipidation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] +synonym: "activation of lipid:protein modification" NARROW [GOC:TermGenie] +synonym: "activation of protein amino acid lipidation" NARROW [GOC:TermGenie] +synonym: "activation of protein lipidation" NARROW [GOC:TermGenie] +synonym: "positive regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "up regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "up regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein lipidation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein lipidation" EXACT [GOC:TermGenie] +synonym: "upregulation of lipid:protein modification" EXACT [GOC:TermGenie] +synonym: "upregulation of protein amino acid lipidation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein lipidation" EXACT [GOC:TermGenie] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:0050747 ! positive regulation of lipoprotein metabolic process +is_a: GO:1903059 ! regulation of protein lipidation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006497 ! protein lipidation +relationship: positively_regulates GO:0006497 ! protein lipidation +created_by: rph +creation_date: 2014-05-28T13:21:31Z + +[Term] +id: GO:1903062 +name: regulation of reverse cholesterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reverse cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23931754] +is_a: GO:0032374 ! regulation of cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043691 ! reverse cholesterol transport +relationship: regulates GO:0043691 ! reverse cholesterol transport +created_by: rl +creation_date: 2014-05-28T15:15:27Z + +[Term] +id: GO:1903063 +name: negative regulation of reverse cholesterol transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23931754] +synonym: "down regulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +synonym: "downregulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +synonym: "inhibition of reverse cholesterol transport" NARROW [GOC:TermGenie] +is_a: GO:0032375 ! negative regulation of cholesterol transport +is_a: GO:1903062 ! regulation of reverse cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043691 ! reverse cholesterol transport +relationship: negatively_regulates GO:0043691 ! reverse cholesterol transport +created_by: rl +creation_date: 2014-05-28T15:15:34Z + +[Term] +id: GO:1903064 +name: positive regulation of reverse cholesterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23931754] +synonym: "activation of reverse cholesterol transport" NARROW [GOC:TermGenie] +synonym: "up regulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +synonym: "upregulation of reverse cholesterol transport" EXACT [GOC:TermGenie] +is_a: GO:0032376 ! positive regulation of cholesterol transport +is_a: GO:1903062 ! regulation of reverse cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043691 ! reverse cholesterol transport +relationship: positively_regulates GO:0043691 ! reverse cholesterol transport +created_by: rl +creation_date: 2014-05-28T15:15:40Z + +[Term] +id: GO:1903065 +name: obsolete protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape +namespace: biological_process +def: "OBSOLETE. Any protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape." [GO_REF:0000060, GOC:TermGenie, PMID:24554432] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [] +is_obsolete: true +created_by: vw +creation_date: 2014-05-28T15:29:27Z + +[Term] +id: GO:1903066 +name: regulation of protein localization to cell tip +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell tip." [GO_REF:0000058, GOC:TermGenie, PMID:24554432] +synonym: "regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990151 ! protein localization to cell tip +relationship: regulates GO:1990151 ! protein localization to cell tip +created_by: vw +creation_date: 2014-05-28T15:48:42Z + +[Term] +id: GO:1903067 +name: negative regulation of protein localization to cell tip +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip." [GO_REF:0000058, GOC:TermGenie, PMID:24554432] +synonym: "down regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to cell tip" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell tip" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell tip" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to cell tip" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to cell tip" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +is_a: GO:1903066 ! regulation of protein localization to cell tip +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990151 ! protein localization to cell tip +relationship: negatively_regulates GO:1990151 ! protein localization to cell tip +created_by: vw +creation_date: 2014-05-28T15:48:48Z + +[Term] +id: GO:1903068 +name: positive regulation of protein localization to cell tip +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell tip." [GO_REF:0000058, GOC:TermGenie, PMID:24554432] +synonym: "activation of protein localisation to cell tip" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to cell tip" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to cell tip" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cell tip" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to cell tip" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cell tip" EXACT [GOC:TermGenie] +is_a: GO:1903066 ! regulation of protein localization to cell tip +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990151 ! protein localization to cell tip +relationship: positively_regulates GO:1990151 ! protein localization to cell tip +created_by: vw +creation_date: 2014-05-28T15:48:54Z + +[Term] +id: GO:1903069 +name: regulation of ER-associated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:17872946] +synonym: "regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of ERAD" EXACT [GOC:TermGenie] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1904292 ! regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +relationship: regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +created_by: rph +creation_date: 2014-05-28T17:53:46Z + +[Term] +id: GO:1903070 +name: negative regulation of ER-associated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:17872946] +synonym: "down regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ERAD" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERAD" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ERAD" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum-associated protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum-associated protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ER-associated protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of ER-associated protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ER-associated protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ER-associated protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of ER-associated ubiquitin-dependent protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ERAD" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ERAD" EXACT [GOC:TermGenie] +is_a: GO:0032435 ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1903069 ! regulation of ER-associated ubiquitin-dependent protein catabolic process +is_a: GO:1904293 ! negative regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +relationship: negatively_regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +created_by: rph +creation_date: 2014-05-28T17:53:53Z + +[Term] +id: GO:1903071 +name: positive regulation of ER-associated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:17872946] +synonym: "activation of endoplasmic reticulum-associated protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum-associated protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of ER-associated protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of ER-associated protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ER-associated protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of ER-associated protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of ER-associated ubiquitin-dependent protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ERAD" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ERAD" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ERAD" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERAD" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ER-associated protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of ER-associated protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ER-associated protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ER-associated protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of ER-associated ubiquitin-dependent protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ERAD" EXACT [GOC:TermGenie] +is_a: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1903069 ! regulation of ER-associated ubiquitin-dependent protein catabolic process +is_a: GO:1904294 ! positive regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +relationship: positively_regulates GO:0030433 ! ubiquitin-dependent ERAD pathway +created_by: rph +creation_date: 2014-05-28T17:54:04Z + +[Term] +id: GO:1903072 +name: regulation of death-inducing signaling complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21785459] +synonym: "regulation of DD-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of death domain-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [GOC:TermGenie] +synonym: "regulation of death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of DISC assembly" EXACT [GOC:TermGenie] +synonym: "regulation of DISC formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:2001236 ! regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071550 ! death-inducing signaling complex assembly +relationship: regulates GO:0071550 ! death-inducing signaling complex assembly +created_by: bf +creation_date: 2014-05-29T09:33:13Z + +[Term] +id: GO:1903073 +name: negative regulation of death-inducing signaling complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21785459] +synonym: "down regulation of DD-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of death domain-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of death-inducing signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of DISC assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of DISC formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DD-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of death domain-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of death-inducing signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of DISC assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of DISC formation" EXACT [GOC:TermGenie] +synonym: "downregulation of DD-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of death domain-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of death-inducing signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of DISC assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of DISC formation" EXACT [GOC:TermGenie] +synonym: "inhibition of DD-mediated complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of death domain-mediated complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of death-inducing signaling complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of death-inducing signaling complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of death-inducing signalling complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of DISC assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of DISC formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of DD-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of death domain-mediated complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of DISC assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of DISC formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1903072 ! regulation of death-inducing signaling complex assembly +is_a: GO:2001237 ! negative regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071550 ! death-inducing signaling complex assembly +relationship: negatively_regulates GO:0071550 ! death-inducing signaling complex assembly +created_by: bf +creation_date: 2014-05-29T09:33:20Z + +[Term] +id: GO:1903074 +name: TRAIL death-inducing signaling complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21785459] +synonym: "TRAIL death-inducing signaling complex formation" EXACT [GOC:TermGenie] +synonym: "TRAIL death-inducing signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "TRAIL death-inducing signalling complex formation" EXACT [GOC:TermGenie] +synonym: "TRAIL DISC assembly" EXACT [GOC:TermGenie] +synonym: "TRAIL DISC formation" EXACT [GOC:TermGenie] +is_a: GO:0071550 ! death-inducing signaling complex assembly +relationship: part_of GO:0036462 ! TRAIL-activated apoptotic signaling pathway +created_by: bf +creation_date: 2014-05-29T09:47:39Z + +[Term] +id: GO:1903075 +name: pyridoxine import across plasma membrane +namespace: biological_process +def: "The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:15701794] +synonym: "pyridoxine import into cell" EXACT [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1903092 ! pyridoxine transmembrane transport +created_by: mah +creation_date: 2014-05-29T15:04:14Z + +[Term] +id: GO:1903076 +name: regulation of protein localization to plasma membrane +namespace: biological_process +alt_id: GO:0090003 +alt_id: GO:1905963 +def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] +synonym: "regulation of establishment of protein localization in plasma membrane" RELATED [] +synonym: "regulation of establishment of protein localization to plasma membrane" RELATED [] +synonym: "regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] +synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein targeting to plasma membrane" RELATED [] +synonym: "regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +is_a: GO:1904375 ! regulation of protein localization to cell periphery +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072659 ! protein localization to plasma membrane +relationship: regulates GO:0072659 ! protein localization to plasma membrane +created_by: tb +creation_date: 2009-07-10T10:32:44Z + +[Term] +id: GO:1903077 +name: negative regulation of protein localization to plasma membrane +namespace: biological_process +alt_id: GO:0090005 +alt_id: GO:1905964 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "down regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "downregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "inhibition of protein localisation in plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein targeting to plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein-plasma membrane targeting" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] +synonym: "negative regulation of establishment of protein localization in plasma membrane" RELATED [] +synonym: "negative regulation of establishment of protein localization to plasma membrane" RELATED [] +synonym: "negative regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein targeting to plasma membrane" RELATED [] +synonym: "negative regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +is_a: GO:1903076 ! regulation of protein localization to plasma membrane +is_a: GO:1904376 ! negative regulation of protein localization to cell periphery +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072659 ! protein localization to plasma membrane +relationship: negatively_regulates GO:0072659 ! protein localization to plasma membrane +created_by: tb +creation_date: 2014-05-29T17:10:16Z + +[Term] +id: GO:1903078 +name: positive regulation of protein localization to plasma membrane +namespace: biological_process +alt_id: GO:0090004 +alt_id: GO:1905965 +def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "activation of protein localisation in plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein targeting to plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein-plasma membrane targeting" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] +synonym: "positive regulation of establishment of protein localization to plasma membrane" RELATED [] +synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein targeting to plasma membrane" RELATED [] +synonym: "positive regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "up regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] +synonym: "upregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] +is_a: GO:1903076 ! regulation of protein localization to plasma membrane +is_a: GO:1904377 ! positive regulation of protein localization to cell periphery +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072659 ! protein localization to plasma membrane +relationship: positively_regulates GO:0072659 ! protein localization to plasma membrane +created_by: tb +creation_date: 2009-07-10T10:34:17Z + +[Term] +id: GO:1903079 +name: obsolete negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape +namespace: biological_process +def: "OBSOLETE. Any negative regulation of protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape." [GO_REF:0000060, GOC:TermGenie, PMID:24554432] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape" EXACT [] +is_obsolete: true +created_by: vw +creation_date: 2014-05-29T17:42:24Z + +[Term] +id: GO:1903080 +name: regulation of C-C chemokine receptor CCR7 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0070099 ! regulation of chemokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +relationship: regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +created_by: rl +creation_date: 2014-05-29T18:32:49Z + +[Term] +id: GO:1903081 +name: negative regulation of C-C chemokine receptor CCR7 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "down regulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of C-C chemokine receptor CCR7 signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of C-C chemokine receptor CCR7 signalling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0070100 ! negative regulation of chemokine-mediated signaling pathway +is_a: GO:1903080 ! regulation of C-C chemokine receptor CCR7 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +relationship: negatively_regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +created_by: rl +creation_date: 2014-05-29T18:32:55Z + +[Term] +id: GO:1903082 +name: positive regulation of C-C chemokine receptor CCR7 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] +synonym: "activation of C-C chemokine receptor CCR7 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of C-C chemokine receptor CCR7 signalling pathway" NARROW [GOC:TermGenie] +synonym: "activation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of C-C chemokine receptor CCR7 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of C-C chemokine receptor CCR7 signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of CCR7 signaling pathway" RELATED [GOC:TermGenie] +is_a: GO:0070101 ! positive regulation of chemokine-mediated signaling pathway +is_a: GO:1903080 ! regulation of C-C chemokine receptor CCR7 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +relationship: positively_regulates GO:0038118 ! C-C chemokine receptor CCR7 signaling pathway +created_by: rl +creation_date: 2014-05-29T18:33:01Z + +[Term] +id: GO:1903083 +name: protein localization to condensed chromosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a condensed chromosome." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, pmid:12707312] +synonym: "protein localisation in condensed chromosome" EXACT [GOC:TermGenie] +synonym: "protein localisation to condensed chromosome" EXACT [GOC:TermGenie] +synonym: "protein localization in condensed chromosome" EXACT [GOC:TermGenie] +is_a: GO:0034502 ! protein localization to chromosome +created_by: kmv +creation_date: 2014-05-29T20:31:25Z + +[Term] +id: GO:1903084 +name: protein localization to condensed nuclear chromosome +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, pmid:12707312] +synonym: "protein localisation in condensed nuclear chromosome" EXACT [GOC:TermGenie] +synonym: "protein localisation to condensed nuclear chromosome" EXACT [GOC:TermGenie] +synonym: "protein localization in condensed nuclear chromosome" EXACT [GOC:TermGenie] +is_a: GO:0034504 ! protein localization to nucleus +is_a: GO:1903083 ! protein localization to condensed chromosome +created_by: kmv +creation_date: 2014-05-29T20:33:17Z + +[Term] +id: GO:1903085 +name: regulation of sinapate ester biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis." [GO_REF:0000058, GOC:TermGenie, PMID:11080161] +synonym: "regulation of sinapate ester anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of sinapate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of sinapate ester formation" EXACT [GOC:TermGenie] +synonym: "regulation of sinapate ester synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +is_a: GO:2000762 ! regulation of phenylpropanoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033525 ! sinapate ester biosynthetic process +relationship: regulates GO:0033525 ! sinapate ester biosynthetic process +created_by: tb +creation_date: 2014-05-30T22:00:12Z + +[Term] +id: GO:1903086 +name: negative regulation of sinapate ester biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis." [GO_REF:0000058, GOC:TermGenie, PMID:11080161] +synonym: "down regulation of sinapate ester anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of sinapate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of sinapate ester biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of sinapate ester formation" EXACT [GOC:TermGenie] +synonym: "down regulation of sinapate ester synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sinapate ester anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of sinapate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sinapate ester biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of sinapate ester formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sinapate ester synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sinapate ester anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of sinapate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sinapate ester biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of sinapate ester formation" EXACT [GOC:TermGenie] +synonym: "downregulation of sinapate ester synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sinapate ester anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of sinapate ester biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of sinapate ester biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of sinapate ester formation" NARROW [GOC:TermGenie] +synonym: "inhibition of sinapate ester synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of sinapate ester anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of sinapate ester biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of sinapate ester formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of sinapate ester synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1903085 ! regulation of sinapate ester biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033525 ! sinapate ester biosynthetic process +relationship: negatively_regulates GO:0033525 ! sinapate ester biosynthetic process +created_by: tb +creation_date: 2014-05-30T22:00:18Z + +[Term] +id: GO:1903087 +name: mitotic spindle pole body duplication +namespace: biological_process +def: "Any spindle pole body duplication that is involved in the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "spindle pole body assembly involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body biogenesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body biosynthesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body duplication associated with nuclear envelope involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body duplication in cytoplasm involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body duplication involved in mitotic cell cycle" EXACT [] +synonym: "spindle pole body formation involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "spindle pole body replication involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0030474 ! spindle pole body duplication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0030474 ! spindle pole body duplication +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2014-06-02T16:45:56Z + +[Term] +id: GO:1903088 +name: 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport +namespace: biological_process +def: "The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:24778186] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0042886 ! amide transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:1901264 ! carbohydrate derivative transport +created_by: mcc +creation_date: 2014-06-02T20:34:58Z + +[Term] +id: GO:1903089 +name: 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other." [GO_REF:0000066, GOC:TermGenie, PMID:24778186] +synonym: "acadesine transporter activity" EXACT [] +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +is_a: GO:1901505 ! carbohydrate derivative transmembrane transporter activity +relationship: part_of GO:1903088 ! 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport +created_by: mcc +creation_date: 2014-06-02T20:37:17Z + +[Term] +id: GO:1903090 +name: pyridoxal transmembrane transport +namespace: biological_process +def: "The process in which pyridoxal is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:15701794] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0031920 ! pyridoxal transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: al +creation_date: 2014-06-03T10:41:13Z + +[Term] +id: GO:1903091 +name: pyridoxamine transmembrane transport +namespace: biological_process +def: "The process in which pyridoxamine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:15701794] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0031922 ! pyridoxamine transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: al +creation_date: 2014-06-03T10:41:20Z + +[Term] +id: GO:1903092 +name: pyridoxine transmembrane transport +namespace: biological_process +def: "The process in which pyridoxine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:15701794] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0031923 ! pyridoxine transport +is_a: GO:0035461 ! vitamin transmembrane transport +created_by: al +creation_date: 2014-06-03T10:41:26Z + +[Term] +id: GO:1903093 +name: regulation of protein K48-linked deubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +is_a: GO:0090085 ! regulation of protein deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071108 ! protein K48-linked deubiquitination +relationship: regulates GO:0071108 ! protein K48-linked deubiquitination +created_by: bf +creation_date: 2014-06-03T12:27:48Z + +[Term] +id: GO:1903094 +name: negative regulation of protein K48-linked deubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21097510] +synonym: "down regulation of protein K48-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein K48-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein K48-linked deubiquitination" EXACT [GOC:TermGenie] +synonym: "inhibition of protein K48-linked deubiquitination" NARROW [GOC:TermGenie] +is_a: GO:0090086 ! negative regulation of protein deubiquitination +is_a: GO:1903093 ! regulation of protein K48-linked deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071108 ! protein K48-linked deubiquitination +relationship: negatively_regulates GO:0071108 ! protein K48-linked deubiquitination +created_by: bf +creation_date: 2014-06-03T12:27:54Z + +[Term] +id: GO:1903095 +name: ribonuclease III complex +namespace: cellular_component +def: "A protein complex which is capable of ribonuclease III activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:22393237] +comment: An example of this is RNC in human (Q9NRR4) in PMID:22393237 (inferred from direct assay). +is_a: GO:1902555 ! endoribonuclease complex +created_by: bhm +creation_date: 2014-06-03T15:06:39Z + +[Term] +id: GO:1903096 +name: protein localization to meiotic spindle midzone +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, pmid:12707312] +synonym: "protein localisation in meiotic spindle midzone" EXACT [GOC:TermGenie] +synonym: "protein localisation to meiotic spindle midzone" EXACT [GOC:TermGenie] +synonym: "protein localization in meiotic spindle midzone" EXACT [GOC:TermGenie] +is_a: GO:1905359 ! protein localization to meiotic spindle +created_by: kmv +creation_date: 2014-06-03T16:06:22Z + +[Term] +id: GO:1903097 +name: regulation of CENP-A containing nucleosome assembly +namespace: biological_process +def: "Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres." [GO_REF:0000058, GOC:TermGenie, PMID:24710126] +synonym: "regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +is_a: GO:0010847 ! regulation of chromatin assembly +is_a: GO:0090230 ! regulation of centromere complex assembly +is_a: GO:1900049 ! regulation of histone exchange +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034080 ! CENP-A containing nucleosome assembly +relationship: regulates GO:0034080 ! CENP-A containing nucleosome assembly +created_by: vw +creation_date: 2014-06-03T16:15:30Z + +[Term] +id: GO:1903098 +name: negative regulation of CENP-A containing nucleosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres." [GO_REF:0000058, GOC:TermGenie, PMID:24710126] +synonym: "down regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "down regulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "down regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "down regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "down regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "down regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "down regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "down-regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "down-regulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "down-regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "down-regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "down-regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "down-regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "down-regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "downregulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "downregulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "downregulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "downregulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "downregulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "downregulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "downregulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "inhibition of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "inhibition of CENP-A containing nucleosome assembly at centromere" NARROW [GOC:TermGenie] +synonym: "inhibition of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "inhibition of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "inhibition of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "inhibition of centromere-specific histone exchange" NARROW [GOC:TermGenie] +synonym: "inhibition of centromere-specific nucleosome assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of centromeric DNA replication-independent nucleosome assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replication-independent nucleosome assembly at centromere" NARROW [GOC:TermGenie] +synonym: "negative regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "negative regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "negative regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "negative regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "negative regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "negative regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0045798 ! negative regulation of chromatin assembly or disassembly +is_a: GO:1900050 ! negative regulation of histone exchange +is_a: GO:1903097 ! regulation of CENP-A containing nucleosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034080 ! CENP-A containing nucleosome assembly +relationship: negatively_regulates GO:0034080 ! CENP-A containing nucleosome assembly +created_by: vw +creation_date: 2014-06-03T16:15:36Z + +[Term] +id: GO:1903099 +name: positive regulation of CENP-A containing nucleosome assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres." [GO_REF:0000058, GOC:TermGenie, PMID:24710126] +synonym: "activation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "activation of CENP-A containing nucleosome assembly at centromere" NARROW [GOC:TermGenie] +synonym: "activation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "activation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "activation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "activation of centromere-specific histone exchange" NARROW [GOC:TermGenie] +synonym: "activation of centromere-specific nucleosome assembly" NARROW [GOC:TermGenie] +synonym: "activation of centromeric DNA replication-independent nucleosome assembly" NARROW [GOC:TermGenie] +synonym: "activation of DNA replication-independent nucleosome assembly at centromere" NARROW [GOC:TermGenie] +synonym: "positive regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "positive regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "positive regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "positive regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "positive regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "positive regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "up regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "up regulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "up regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "up regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "up regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "up regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "up regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "up-regulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "up-regulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "up-regulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "up-regulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "up-regulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "up-regulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "up-regulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "upregulation of CenH3-containing nucleosome assembly at centromere" RELATED [GOC:TermGenie] +synonym: "upregulation of CENP-A containing nucleosome assembly at centromere" EXACT [GOC:TermGenie] +synonym: "upregulation of CENP-A deposition" RELATED [GOC:TermGenie] +synonym: "upregulation of CENP-A loading" RELATED [GOC:TermGenie] +synonym: "upregulation of centromere specific nucleosome exchange" RELATED [GOC:TermGenie] +synonym: "upregulation of centromere-specific histone exchange" EXACT [GOC:TermGenie] +synonym: "upregulation of centromere-specific nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of centromeric DNA replication-independent nucleosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA replication-independent nucleosome assembly at centromere" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0045799 ! positive regulation of chromatin assembly or disassembly +is_a: GO:1900051 ! positive regulation of histone exchange +is_a: GO:1903097 ! regulation of CENP-A containing nucleosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034080 ! CENP-A containing nucleosome assembly +relationship: positively_regulates GO:0034080 ! CENP-A containing nucleosome assembly +created_by: vw +creation_date: 2014-06-03T16:15:42Z + +[Term] +id: GO:1903100 +name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate." [GO_REF:0000068, GOC:bhm, GOC:TermGenie, PMID:19037259] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +created_by: bhm +creation_date: 2014-06-04T14:14:24Z + +[Term] +id: GO:1903101 +name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate." [GO_REF:0000068, GOC:bhm, GOC:TermGenie, PMID:19037259] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate breakdown" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolism" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate degradation" EXACT [GOC:TermGenie] +is_a: GO:0031161 ! phosphatidylinositol catabolic process +is_a: GO:1903100 ! 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process +created_by: bhm +creation_date: 2014-06-04T14:14:30Z + +[Term] +id: GO:1903102 +name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate." [GO_REF:0000068, GOC:bhm, GOC:TermGenie, PMID:19037259] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate anabolism" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate formation" EXACT [GOC:TermGenie] +synonym: "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006661 ! phosphatidylinositol biosynthetic process +is_a: GO:1903100 ! 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process +created_by: bhm +creation_date: 2014-06-04T14:14:36Z + +[Term] +id: GO:1903103 +name: potassium:proton antiporter complex +namespace: cellular_component +def: "A protein complex which is capable of potassium:proton antiporter activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:21041667] +comment: An example of this is kefC in E. coli (P03819) in PMID:21041667 (inferred from direct assay). +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2014-06-04T20:51:33Z + +[Term] +id: GO:1903104 +name: regulation of insulin receptor signaling pathway involved in determination of adult lifespan +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:19853560] +synonym: "regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +is_a: GO:0046626 ! regulation of insulin receptor signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +relationship: regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +created_by: kmv +creation_date: 2014-06-05T20:56:06Z + +[Term] +id: GO:1903105 +name: negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:19853560] +synonym: "down regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "down regulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "down regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "down regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "down-regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "down-regulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "down-regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "down-regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "downregulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "downregulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "downregulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "downregulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "inhibition of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "inhibition of insulin receptor signaling pathway involved in determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "inhibition of insulin receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "inhibition of insulin receptor signalling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "negative regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "negative regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "negative regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +is_a: GO:0046627 ! negative regulation of insulin receptor signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903104 ! regulation of insulin receptor signaling pathway involved in determination of adult lifespan +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +relationship: negatively_regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +created_by: kmv +creation_date: 2014-06-05T20:56:12Z + +[Term] +id: GO:1903106 +name: positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:19853560] +synonym: "activation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "activation of insulin receptor signaling pathway involved in determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "activation of insulin receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "activation of insulin receptor signalling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "positive regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "positive regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "positive regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "up regulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up-regulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "up-regulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up-regulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "up-regulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "upregulation of daf-2 receptor signaling pathway of determination of adult lifespan" NARROW [GOC:TermGenie] +synonym: "upregulation of insulin receptor signaling pathway involved in determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "upregulation of insulin receptor signaling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +synonym: "upregulation of insulin receptor signalling pathway of determination of adult lifespan" EXACT [GOC:TermGenie] +is_a: GO:0046628 ! positive regulation of insulin receptor signaling pathway +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903104 ! regulation of insulin receptor signaling pathway involved in determination of adult lifespan +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +relationship: positively_regulates GO:1901047 ! insulin receptor signaling pathway involved in determination of adult lifespan +created_by: kmv +creation_date: 2014-06-05T20:56:19Z + +[Term] +id: GO:1903107 +name: insulin receptor signaling pathway involved in dauer larval development +namespace: biological_process +def: "Any insulin receptor signaling pathway that is involved in dauer larval development." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:19853560] +synonym: "daf-2 receptor signaling pathway involved in dauer larval development" NARROW [GOC:TermGenie] +synonym: "insulin receptor signalling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +is_a: GO:0008286 ! insulin receptor signaling pathway +intersection_of: GO:0008286 ! insulin receptor signaling pathway +intersection_of: part_of GO:0040024 ! dauer larval development +relationship: part_of GO:0040024 ! dauer larval development +created_by: kmv +creation_date: 2014-06-05T21:30:03Z + +[Term] +id: GO:1903108 +name: regulation of mitochondrial transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:21357609] +synonym: "regulation of mitochondrial transcription" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from mitochondrial promoter" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:0062125 ! regulation of mitochondrial gene expression +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006390 ! mitochondrial transcription +relationship: regulates GO:0006390 ! mitochondrial transcription +created_by: al +creation_date: 2014-06-09T11:53:14Z + +[Term] +id: GO:1903109 +name: positive regulation of mitochondrial transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:21357609] +synonym: "activation of mitochondrial transcription" NARROW [GOC:TermGenie] +synonym: "activation of transcription from mitochondrial promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial transcription" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from mitochondrial promoter" EXACT [] +synonym: "up regulation of mitochondrial transcription" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from mitochondrial promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial transcription" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from mitochondrial promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial transcription" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from mitochondrial promoter" EXACT [GOC:TermGenie] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:1903108 ! regulation of mitochondrial transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006390 ! mitochondrial transcription +relationship: positively_regulates GO:0006390 ! mitochondrial transcription +created_by: al +creation_date: 2014-06-09T11:53:20Z + +[Term] +id: GO:1903110 +name: regulation of single-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:24339919] +is_a: GO:0000018 ! regulation of DNA recombination +is_a: GO:1903516 ! regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990396 ! single-strand break repair via homologous recombination +relationship: regulates GO:1990396 ! single-strand break repair via homologous recombination +created_by: pr +creation_date: 2014-06-09T12:11:26Z + +[Term] +id: GO:1903111 +name: negative regulation of single-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:24339919] +synonym: "down regulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "down-regulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "downregulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "inhibition of single-strand break repair via homologous recombination" NARROW [GOC:TermGenie] +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:1903110 ! regulation of single-strand break repair via homologous recombination +is_a: GO:1903517 ! negative regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990396 ! single-strand break repair via homologous recombination +relationship: negatively_regulates GO:1990396 ! single-strand break repair via homologous recombination +created_by: pr +creation_date: 2014-06-09T12:11:32Z + +[Term] +id: GO:1903112 +name: positive regulation of single-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:24339919] +synonym: "activation of single-strand break repair via homologous recombination" NARROW [GOC:TermGenie] +synonym: "up regulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "up-regulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "upregulation of single-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:1903110 ! regulation of single-strand break repair via homologous recombination +is_a: GO:1903518 ! positive regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990396 ! single-strand break repair via homologous recombination +relationship: positively_regulates GO:1990396 ! single-strand break repair via homologous recombination +created_by: pr +creation_date: 2014-06-09T12:11:38Z + +[Term] +id: GO:1903113 +name: copper ion transmembrane transporter complex +namespace: cellular_component +def: "A protein complex which is capable of copper ion transmembrane transporter activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:23122209] +comment: An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209 (inferred from direct assay). +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2014-06-10T09:54:48Z + +[Term] +id: GO:1903114 +name: silver ion transmembrane transporter complex +namespace: cellular_component +def: "A protein complex which is capable of silver ion transmembrane transporter activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:11283292] +comment: An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:11283292 (inferred from direct assay). +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2014-06-10T10:00:02Z + +[Term] +id: GO:1903115 +name: regulation of actin filament-based movement +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] +is_a: GO:0032970 ! regulation of actin filament-based process +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030048 ! actin filament-based movement +relationship: regulates GO:0030048 ! actin filament-based movement +created_by: al +creation_date: 2014-06-12T16:55:57Z + +[Term] +id: GO:1903116 +name: positive regulation of actin filament-based movement +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] +synonym: "activation of actin filament-based movement" NARROW [GOC:TermGenie] +synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie] +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030048 ! actin filament-based movement +relationship: positively_regulates GO:0030048 ! actin filament-based movement +created_by: al +creation_date: 2014-06-12T16:56:04Z + +[Term] +id: GO:1903117 +name: regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] +synonym: "regulation of actin filament organisation of constriction ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organisation of contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "regulation of actin filament organisation of cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "regulation of actin filament organisation of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organisation of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organisation of cytokinesis, actomyosin ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organisation of cytokinesis, contractile ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organization of constriction ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organization of contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "regulation of actin filament organization of cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "regulation of actin filament organization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organization of cytokinesis, actomyosin ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of actin filament organization of cytokinesis, contractile ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of constriction ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of contractile ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of cytokinesis, actomyosin ring formation" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of actin filament localization of cytokinesis, contractile ring assembly" RELATED [GOC:TermGenie] +is_a: GO:0110053 ! regulation of actin filament organization +is_a: GO:2000431 ! regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000689 ! actomyosin contractile ring assembly actin filament organization +relationship: regulates GO:2000689 ! actomyosin contractile ring assembly actin filament organization +created_by: al +creation_date: 2014-06-12T16:57:17Z + +[Term] +id: GO:1903118 +name: urate homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of urate within an organism or cell." [GO_REF:0000072, GOC:dph, GOC:TermGenie, PMID:22306318] +is_a: GO:0048878 ! chemical homeostasis +created_by: dph +creation_date: 2014-06-13T14:54:51Z + +[Term] +id: GO:1903119 +name: protein localization to actin cytoskeleton +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] +synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie] +synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie] +synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie] +is_a: GO:0044380 ! protein localization to cytoskeleton +created_by: mah +creation_date: 2014-06-16T11:27:09Z + +[Term] +id: GO:1903120 +name: protein localization to actin filament bundle +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] +synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie] +synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie] +synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie] +synonym: "protein localization to actin cable" RELATED [GOC:mah] +is_a: GO:1903119 ! protein localization to actin cytoskeleton +created_by: mah +creation_date: 2014-06-16T11:27:16Z + +[Term] +id: GO:1903121 +name: regulation of TRAIL-activated apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1902041 ! regulation of extrinsic apoptotic signaling pathway via death domain receptors +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +relationship: regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +created_by: bf +creation_date: 2014-06-17T12:39:15Z + +[Term] +id: GO:1903122 +name: negative regulation of TRAIL-activated apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21785459] +synonym: "down regulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of TRAIL-activated apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of TRAIL-activated extrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of TRAIL-induced apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1902042 ! negative regulation of extrinsic apoptotic signaling pathway via death domain receptors +is_a: GO:1903121 ! regulation of TRAIL-activated apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +relationship: negatively_regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +created_by: bf +creation_date: 2014-06-17T12:39:21Z + +[Term] +id: GO:1903123 +name: regulation of thioredoxin peroxidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of thiol peroxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of TPx activity" EXACT [GOC:TermGenie] +synonym: "regulation of TrxPx activity" EXACT [GOC:TermGenie] +is_a: GO:2000468 ! regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008379 ! thioredoxin peroxidase activity +relationship: regulates GO:0008379 ! thioredoxin peroxidase activity +created_by: bf +creation_date: 2014-06-18T11:03:11Z + +[Term] +id: GO:1903124 +name: negative regulation of thioredoxin peroxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21850687] +synonym: "down regulation of thiol peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of thioredoxin peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of TPx activity" EXACT [GOC:TermGenie] +synonym: "down regulation of TrxPx activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of thiol peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of thioredoxin peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of TPx activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of TrxPx activity" EXACT [GOC:TermGenie] +synonym: "downregulation of thiol peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of thioredoxin peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of TPx activity" EXACT [GOC:TermGenie] +synonym: "downregulation of TrxPx activity" EXACT [GOC:TermGenie] +synonym: "inhibition of thiol peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of thioredoxin peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of TPx activity" NARROW [GOC:TermGenie] +synonym: "inhibition of TrxPx activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of thiol peroxidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of TPx activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of TrxPx activity" EXACT [GOC:TermGenie] +is_a: GO:1903123 ! regulation of thioredoxin peroxidase activity +is_a: GO:2000469 ! negative regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008379 ! thioredoxin peroxidase activity +relationship: negatively_regulates GO:0008379 ! thioredoxin peroxidase activity +created_by: bf +creation_date: 2014-06-18T11:03:26Z + +[Term] +id: GO:1903125 +name: negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation +namespace: biological_process +def: "A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity." [GO_REF:0000063, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21850687] +synonym: "negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TPx activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TrxPx activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0018107 ! peptidyl-threonine phosphorylation +is_a: GO:1903124 ! negative regulation of thioredoxin peroxidase activity +intersection_of: GO:0018107 ! peptidyl-threonine phosphorylation +intersection_of: negatively_regulates GO:0008379 ! thioredoxin peroxidase activity +created_by: bf +creation_date: 2014-06-24T08:47:25Z + +[Term] +id: GO:1903126 +name: negative regulation of centriole-centriole cohesion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24554434] +synonym: "down regulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +synonym: "downregulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +synonym: "inhibition of centriole-centriole cohesion" NARROW [GOC:TermGenie] +is_a: GO:0030997 ! regulation of centriole-centriole cohesion +is_a: GO:0046606 ! negative regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010457 ! centriole-centriole cohesion +relationship: negatively_regulates GO:0010457 ! centriole-centriole cohesion +created_by: als +creation_date: 2014-06-24T09:31:45Z + +[Term] +id: GO:1903127 +name: positive regulation of centriole-centriole cohesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24554434] +synonym: "activation of centriole-centriole cohesion" NARROW [GOC:TermGenie] +synonym: "up regulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +synonym: "upregulation of centriole-centriole cohesion" EXACT [GOC:TermGenie] +is_a: GO:0030997 ! regulation of centriole-centriole cohesion +is_a: GO:0046607 ! positive regulation of centrosome cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010457 ! centriole-centriole cohesion +relationship: positively_regulates GO:0010457 ! centriole-centriole cohesion +created_by: als +creation_date: 2014-06-24T09:31:51Z + +[Term] +id: GO:1903131 +name: mononuclear cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906] +is_a: GO:0002521 ! leukocyte differentiation +created_by: cls +creation_date: 2014-06-25T15:47:09Z + +[Term] +id: GO:1903132 +name: regulation of tube lumen cavitation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tube lumen cavitation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:22898778] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060605 ! tube lumen cavitation +relationship: regulates GO:0060605 ! tube lumen cavitation +created_by: dph +creation_date: 2014-06-25T20:18:58Z + +[Term] +id: GO:1903133 +name: negative regulation of tube lumen cavitation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:22898778] +synonym: "inhibition of tube lumen cavitation" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903132 ! regulation of tube lumen cavitation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060605 ! tube lumen cavitation +relationship: negatively_regulates GO:0060605 ! tube lumen cavitation +created_by: dph +creation_date: 2014-06-25T20:19:04Z + +[Term] +id: GO:1903134 +name: trehalose catabolic process involved in cellular response to stress +namespace: biological_process +def: "Any trehalose catabolic process that is involved in cellular response to stress." [GO_REF:0000060, GOC:TermGenie, PMID:15965643] +synonym: "mycose catabolic process involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "mycose catabolism involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "mykose catabolic process involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "mykose catabolism involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "trehalose breakdown involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "trehalose catabolism involved in cellular response to stress" EXACT [GOC:TermGenie] +synonym: "trehalose degradation involved in cellular response to stress" EXACT [GOC:TermGenie] +is_a: GO:0005993 ! trehalose catabolic process +is_a: GO:0070413 ! trehalose metabolism in response to stress +intersection_of: GO:0005993 ! trehalose catabolic process +intersection_of: part_of GO:0033554 ! cellular response to stress +relationship: part_of GO:0010353 ! response to trehalose +created_by: al +creation_date: 2014-06-25T22:28:34Z + +[Term] +id: GO:1903135 +name: cupric ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cupric ion, copper(2+)." [GO_REF:0000067, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24567322] +synonym: "copper(2+)binding" EXACT [CHEBI:29036] +synonym: "Cu(2+) binding" EXACT [CHEBI:29036] +synonym: "Cu(II) binding" EXACT [PMID:24567322] +is_a: GO:0005507 ! copper ion binding +created_by: bf +creation_date: 2014-06-26T14:38:16Z + +[Term] +id: GO:1903136 +name: cuprous ion binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cuprous ion, copper(1+)." [GO_REF:0000067, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24567322] +synonym: "copper(1+) binding" EXACT [CHEBI:49552] +synonym: "Cu(+) binding" EXACT [CHEBI:49552] +synonym: "Cu(I) binding" EXACT [PMID:24567322] +is_a: GO:0005507 ! copper ion binding +created_by: bf +creation_date: 2014-06-26T14:38:23Z + +[Term] +id: GO:1903137 +name: regulation of MAPK cascade involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23934882] +synonym: "regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "regulation of Slt2 cascade" NARROW [GOC:TermGenie] +is_a: GO:0032872 ! regulation of stress-activated MAPK cascade +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000196 ! cell wall integrity MAPK cascade +relationship: regulates GO:0000196 ! cell wall integrity MAPK cascade +created_by: mah +creation_date: 2014-07-01T10:21:53Z + +[Term] +id: GO:1903138 +name: negative regulation of MAPK cascade involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23934882] +synonym: "down regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "down regulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "down regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "down regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "down regulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "down-regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "down-regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "down-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "down-regulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "downregulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "downregulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "downregulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "downregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "downregulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of cell integrity MAPK pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of cell wall biogenesis, MAPKKK cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPK cascade involved in cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPKKK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "negative regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "negative regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of Slt2 cascade" NARROW [GOC:TermGenie] +is_a: GO:0032873 ! negative regulation of stress-activated MAPK cascade +is_a: GO:1903137 ! regulation of MAPK cascade involved in cell wall organization or biogenesis +is_a: GO:1903339 ! negative regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000196 ! cell wall integrity MAPK cascade +relationship: negatively_regulates GO:0000196 ! cell wall integrity MAPK cascade +created_by: mah +creation_date: 2014-07-01T10:21:59Z + +[Term] +id: GO:1903139 +name: positive regulation of MAPK cascade involved in cell wall organization or biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23934882] +synonym: "activation of cell integrity MAPK pathway" NARROW [GOC:TermGenie] +synonym: "activation of cell wall biogenesis, MAPKKK cascade" NARROW [GOC:TermGenie] +synonym: "activation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of MAPK cascade involved in cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of MAPKKK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "activation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "activation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "activation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "activation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "positive regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "positive regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "positive regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "positive regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "up regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "up regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "up regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "up-regulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "up-regulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "up-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of Slt2 cascade" NARROW [GOC:TermGenie] +synonym: "upregulation of cell integrity MAPK pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of cell wall biogenesis, MAPKKK cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of MAPK cascade involved in cell wall biogenesis" NARROW [GOC:TermGenie] +synonym: "upregulation of MAPK cascade involved in cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of MAPKKK cascade involved in cell wall biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Mpk1 cascade" NARROW [GOC:TermGenie] +synonym: "upregulation of Pmk1 MAPK cell integrity signaling" NARROW [GOC:TermGenie] +synonym: "upregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of PMK1-MAPK signal transduction pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of Slt2 cascade" NARROW [GOC:TermGenie] +is_a: GO:0032874 ! positive regulation of stress-activated MAPK cascade +is_a: GO:1903137 ! regulation of MAPK cascade involved in cell wall organization or biogenesis +is_a: GO:1903340 ! positive regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000196 ! cell wall integrity MAPK cascade +relationship: positively_regulates GO:0000196 ! cell wall integrity MAPK cascade +created_by: mah +creation_date: 2014-07-01T10:22:05Z + +[Term] +id: GO:1903140 +name: regulation of establishment of endothelial barrier +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of endothelial barrier." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24851274] +is_a: GO:1901550 ! regulation of endothelial cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061028 ! establishment of endothelial barrier +relationship: regulates GO:0061028 ! establishment of endothelial barrier +created_by: als +creation_date: 2014-07-01T12:12:34Z + +[Term] +id: GO:1903141 +name: negative regulation of establishment of endothelial barrier +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24851274] +synonym: "down regulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of endothelial barrier" NARROW [GOC:TermGenie] +is_a: GO:1901551 ! negative regulation of endothelial cell development +is_a: GO:1903140 ! regulation of establishment of endothelial barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061028 ! establishment of endothelial barrier +relationship: negatively_regulates GO:0061028 ! establishment of endothelial barrier +created_by: als +creation_date: 2014-07-01T12:12:40Z + +[Term] +id: GO:1903142 +name: positive regulation of establishment of endothelial barrier +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24851274] +synonym: "activation of establishment of endothelial barrier" NARROW [GOC:TermGenie] +synonym: "up regulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of endothelial barrier" EXACT [GOC:TermGenie] +is_a: GO:1901552 ! positive regulation of endothelial cell development +is_a: GO:1903140 ! regulation of establishment of endothelial barrier +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061028 ! establishment of endothelial barrier +relationship: positively_regulates GO:0061028 ! establishment of endothelial barrier +created_by: als +creation_date: 2014-07-01T12:12:52Z + +[Term] +id: GO:1903143 +name: adrenomedullin receptor complex +namespace: cellular_component +def: "A transmembrane, G protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:22102369] +comment: An example of this is RAMP2 in human (O60895) in PMID:22102369 (inferred from direct assay). +synonym: "adrenomedullin receptor AM1 complex" NARROW [] +synonym: "adrenomedullin receptor AM2 complex" NARROW [] +is_a: GO:0038037 ! G protein-coupled receptor dimeric complex +is_a: GO:1903439 ! calcitonin family receptor complex +created_by: bhm +creation_date: 2014-07-02T08:56:47Z + +[Term] +id: GO:1903144 +name: actomyosin contractile ring actin filament +namespace: cellular_component +def: "Any actin filament that is part of a actomyosin contractile ring." [GO_REF:0000064, GOC:TermGenie, PMID:20807799, PMID:24954052] +synonym: "actin filament of actomyosin contractile ring" EXACT [GOC:TermGenie] +synonym: "actin filament of actomyosin ring" EXACT [GOC:TermGenie] +synonym: "actin filament of CAR" EXACT [GOC:TermGenie] +synonym: "actin filament of contractile actomyosin ring" EXACT [GOC:TermGenie] +synonym: "actin filament of cytokinetic ring" EXACT [GOC:TermGenie] +is_a: GO:0005884 ! actin filament +intersection_of: GO:0005884 ! actin filament +intersection_of: part_of GO:0005826 ! actomyosin contractile ring +relationship: part_of GO:0005826 ! actomyosin contractile ring +created_by: vw +creation_date: 2014-07-06T16:20:05Z + +[Term] +id: GO:1903145 +name: actin filament of cell cortex of cell tip +namespace: cellular_component +def: "Any actin filament that is part of a cell cortex of cell tip." [GO_REF:0000064, GOC:TermGenie, PMID:20807799, PMID:24954052] +synonym: "actin filament of cell cortex of cell end" EXACT [GOC:TermGenie] +synonym: "microfilament of cell cortex of cell end" EXACT [GOC:TermGenie] +synonym: "microfilament of cell cortex of cell tip" EXACT [GOC:TermGenie] +is_a: GO:0005884 ! actin filament +intersection_of: GO:0005884 ! actin filament +intersection_of: part_of GO:0051285 ! cell cortex of cell tip +relationship: part_of GO:0051285 ! cell cortex of cell tip +created_by: vw +creation_date: 2014-07-06T16:24:01Z + +[Term] +id: GO:1903146 +name: regulation of autophagy of mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process." [GO_REF:0000058, GOC:autophagy, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24600391] +synonym: "regulation of mitochondrion degradation" BROAD [GOC:TermGenie] +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:0010821 ! regulation of mitochondrion organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000422 ! autophagy of mitochondrion +relationship: regulates GO:0000422 ! autophagy of mitochondrion +created_by: bf +creation_date: 2014-07-09T08:23:51Z + +[Term] +id: GO:1903147 +name: negative regulation of autophagy of mitochondrion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy." [GO_REF:0000058, GOC:autophagy, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24600391] +synonym: "down regulation of mitochondrial degradation" BROAD [GOC:TermGenie] +synonym: "down regulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "down-regulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "down-regulation of mitophagy" BROAD [GOC:TermGenie] +synonym: "downregulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "inhibition of mitochondrion degradation" RELATED [GOC:TermGenie] +synonym: "inhibition of mitophagy" NARROW [GOC:TermGenie] +is_a: GO:0010507 ! negative regulation of autophagy +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:1903146 ! regulation of autophagy of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000422 ! autophagy of mitochondrion +relationship: negatively_regulates GO:0000422 ! autophagy of mitochondrion +created_by: bf +creation_date: 2014-07-09T08:23:58Z + +[Term] +id: GO:1903148 +name: obsolete uracil transmembrane transporter activity involved in uracil import into cell +namespace: molecular_function +def: "OBSOLETE. Any uracil transmembrane transporter activity that is involved in uracil import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "uracil transmembrane transporter activity involved in uracil import into cell" EXACT [] +synonym: "uracil/uridine permease activity involved in uracil import into cell" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:24Z + +[Term] +id: GO:1903149 +name: obsolete adenine transmembrane transporter activity involved in adenine import into cell +namespace: molecular_function +def: "OBSOLETE. Any adenine transmembrane transporter activity that is involved in adenine import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "adenine transmembrane transporter activity involved in adenine import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:30Z + +[Term] +id: GO:1903150 +name: obsolete calcium ion transmembrane transporter activity involved in calcium ion import into cell +namespace: molecular_function +def: "OBSOLETE. Any calcium ion transmembrane transporter activity that is involved in calcium ion import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "calcium ion transmembrane transporter activity involved in calcium ion import into cell" EXACT [] +synonym: "calcium ion transmembrane transporter activity involved in calcium ion uptake into cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:36Z + +[Term] +id: GO:1903151 +name: obsolete carbohydrate transmembrane transporter activity involved in carbohydrate import into cell +namespace: molecular_function +def: "OBSOLETE. Any carbohydrate transmembrane transporter activity that is involved in carbohydrate import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "carbohydrate transmembrane transporter activity involved in carbohydrate import into cell" EXACT [] +synonym: "sugar transporter involved in carbohydrate import into cell" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:42Z + +[Term] +id: GO:1903152 +name: obsolete copper ion transmembrane transporter activity involved in copper ion import into cell +namespace: molecular_function +def: "OBSOLETE. Any copper ion transmembrane transporter activity that is involved in copper ion import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "copper ion transmembrane transporter activity involved in copper cation import into cell" EXACT [GOC:TermGenie] +synonym: "copper ion transmembrane transporter activity involved in copper ion import into cell" EXACT [] +synonym: "intracellular copper ion transporter involved in copper cation import into cell" NARROW [GOC:TermGenie] +synonym: "intracellular copper ion transporter involved in copper ion import into cell" NARROW [GOC:TermGenie] +synonym: "plasma membrane copper transporter involved in copper cation import into cell" NARROW [GOC:TermGenie] +synonym: "plasma membrane copper transporter involved in copper ion import into cell" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:47Z + +[Term] +id: GO:1903153 +name: obsolete ferrous iron transmembrane transporter activity involved in ferrous iron import into cell +namespace: molecular_function +def: "OBSOLETE. Any ferrous iron transmembrane transporter activity that is involved in ferrous iron import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "ferrous iron transmembrane transporter activity involved in ferrous ion import into cell" EXACT [GOC:TermGenie] +synonym: "ferrous iron transmembrane transporter activity involved in ferrous iron import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:53Z + +[Term] +id: GO:1903154 +name: obsolete glucose transmembrane transporter activity involved in glucose import into cell +namespace: molecular_function +def: "OBSOLETE. Any glucose transmembrane transporter activity that is involved in glucose import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "galactose/glucose (methylgalactoside) porter activity involved in glucose import into cell" RELATED [GOC:TermGenie] +synonym: "glucose permease activity involved in glucose import into cell" EXACT [GOC:TermGenie] +synonym: "glucose transmembrane transporter activity involved in glucose import into cell" EXACT [] +synonym: "lactose/glucose efflux transporter activity involved in glucose import into cell" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:55:59Z + +[Term] +id: GO:1903155 +name: obsolete glutathione transmembrane transporter activity involved in glutathione import into cell +namespace: molecular_function +def: "OBSOLETE. Any glutathione transmembrane transporter activity that is involved in glutathione import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "glutathione transmembrane transporter activity involved in glutathione import into cell" EXACT [] +synonym: "glutathione transmembrane transporter activity involved in glutathione uptake" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:05Z + +[Term] +id: GO:1903156 +name: obsolete guanine transmembrane transporter activity involved in guanine import into cell +namespace: molecular_function +def: "OBSOLETE. Any guanine transmembrane transporter activity that is involved in guanine import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "guanine transmembrane transporter activity involved in guanine import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:10Z + +[Term] +id: GO:1903157 +name: obsolete iron ion transmembrane transporter activity involved in iron ion import into cell +namespace: molecular_function +def: "OBSOLETE. Any iron ion transmembrane transporter activity that is involved in iron ion import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "iron ion transmembrane transporter activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "iron ion transmembrane transporter activity involved in iron ion import into cell" EXACT [] +synonym: "iron transporter activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "iron transporter activity involved in iron ion import into cell" EXACT [GOC:TermGenie] +synonym: "multicopper ferroxidase iron transport mediator activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "multicopper ferroxidase iron transport mediator activity involved in iron ion import into cell" RELATED [GOC:TermGenie] +synonym: "transmembrane iron ion permease activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "transmembrane iron ion permease activity involved in iron ion import into cell" EXACT [GOC:TermGenie] +synonym: "transmembrane iron permease activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "transmembrane iron permease activity involved in iron ion import into cell" EXACT [GOC:TermGenie] +synonym: "zinc, iron permease activity involved in iron import into cell" RELATED [GOC:TermGenie] +synonym: "zinc, iron permease activity involved in iron ion import into cell" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:16Z + +[Term] +id: GO:1903158 +name: obsolete L-glutamate transmembrane transporter activity involved in L-glutamate import into cell +namespace: molecular_function +def: "OBSOLETE. Any L-glutamate transmembrane transporter activity that is involved in L-glutamate import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "glutamate/aspartate porter activity involved in L-glutamate import into cell" NARROW [GOC:TermGenie] +synonym: "glutamate/aspartate:sodium symporter activity involved in L-glutamate import into cell" NARROW [GOC:TermGenie] +synonym: "L-glutamate transmembrane transporter activity involved in L-glutamate import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:21Z + +[Term] +id: GO:1903159 +name: obsolete malate transmembrane transporter activity involved in malate import into cell +namespace: molecular_function +def: "OBSOLETE. Any malate transmembrane transporter activity that is involved in malate import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity involved in malate import into cell" RELATED [GOC:TermGenie] +synonym: "malate transmembrane transporter activity involved in malate import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:27Z + +[Term] +id: GO:1903160 +name: obsolete nickel cation transmembrane transporter activity involved in nickel cation import into cell +namespace: molecular_function +def: "OBSOLETE. Any nickel cation transmembrane transporter activity that is involved in nickel cation import into cell." [GO_REF:0000061, GOC:dos, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "nickel cation transmembrane transporter activity involved in nickel cation import into cell" EXACT [] +synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity involved in nickel cation import into cell" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:33Z + +[Term] +id: GO:1903161 +name: obsolete pantothenate transmembrane transporter activity involved in pantothenate import into cell +namespace: molecular_function +def: "OBSOLETE. Any pantothenate transmembrane transporter activity that is involved in pantothenate import into cell." [GO_REF:0000061, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "pantothenate transmembrane transporter activity involved in pantothenate import into cell" EXACT [] +synonym: "vitamin B5 transmembrane transporter activity involved in pantothenate import into cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:38Z + +[Term] +id: GO:1903162 +name: obsolete serine transmembrane transporter activity involved in serine import into cell +namespace: molecular_function +def: "OBSOLETE. Any serine transmembrane transporter activity that is involved in serine import into cell." [GO_REF:0000061, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "serine transmembrane transporter activity involved in serine import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:44Z + +[Term] +id: GO:1903163 +name: obsolete sodium ion transmembrane transporter activity involved in sodium ion import into cell +namespace: molecular_function +def: "OBSOLETE. Any sodium ion transmembrane transporter activity that is involved in sodium ion import into cell." [GO_REF:0000061, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "sodium ion transmembrane transporter activity involved in sodium ion import into cell" EXACT [] +synonym: "sodium transporter activity involved in sodium ion import into cell" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:49Z + +[Term] +id: GO:1903164 +name: obsolete succinate transmembrane transporter activity involved in succinate import into cell +namespace: molecular_function +def: "OBSOLETE. Any succinate transmembrane transporter activity that is involved in succinate import into cell." [GO_REF:0000061, GOC:TermGenie, ISBN:0-8249-3695-6] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity involved in succinate import into cell" RELATED [GOC:TermGenie] +synonym: "succinate transmembrane transporter activity involved in succinate import into cell" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2014-07-09T11:56:55Z + +[Term] +id: GO:1903165 +name: response to polycyclic arene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:10998501] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +created_by: mr +creation_date: 2014-07-09T18:32:59Z + +[Term] +id: GO:1903166 +name: cellular response to polycyclic arene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:10998501] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1903165 ! response to polycyclic arene +created_by: mr +creation_date: 2014-07-09T18:33:04Z + +[Term] +id: GO:1903167 +name: regulation of pyrroline-5-carboxylate reductase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of 1-pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-proline oxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of P5CR activity" EXACT [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004735 ! pyrroline-5-carboxylate reductase activity +relationship: regulates GO:0004735 ! pyrroline-5-carboxylate reductase activity +created_by: bf +creation_date: 2014-07-09T19:51:19Z + +[Term] +id: GO:1903168 +name: positive regulation of pyrroline-5-carboxylate reductase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23743200] +synonym: "activation of 1-pyrroline-5-carboxylate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-proline oxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-proline-NAD(P)+ 5-oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-proline:NAD(P)+ 5-oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of P5CR activity" NARROW [GOC:TermGenie] +synonym: "activation of pyrroline-5-carboxylate reductase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1-pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-proline oxidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of P5CR activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-proline oxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of P5CR activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-proline oxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of P5CR activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-proline oxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of P5CR activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrroline-5-carboxylate reductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1903167 ! regulation of pyrroline-5-carboxylate reductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004735 ! pyrroline-5-carboxylate reductase activity +relationship: positively_regulates GO:0004735 ! pyrroline-5-carboxylate reductase activity +created_by: bf +creation_date: 2014-07-09T19:51:25Z + +[Term] +id: GO:1903169 +name: regulation of calcium ion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24125847] +comment: human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol +synonym: "regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0051924 ! regulation of calcium ion transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070588 ! calcium ion transmembrane transport +relationship: regulates GO:0070588 ! calcium ion transmembrane transport +created_by: rl +creation_date: 2014-07-11T17:09:26Z + +[Term] +id: GO:1903170 +name: negative regulation of calcium ion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24125847] +comment: human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol +synonym: "down regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion membrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of transmembrane calcium transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "negative regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0051926 ! negative regulation of calcium ion transport +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070588 ! calcium ion transmembrane transport +relationship: negatively_regulates GO:0070588 ! calcium ion transmembrane transport +created_by: rl +creation_date: 2014-07-11T17:09:32Z + +[Term] +id: GO:1903171 +name: carbon dioxide homeostasis +namespace: biological_process +def: "Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell." [GO_REF:0000072, GOC:mr, GOC:TermGenie, PMID:16571594] +is_a: GO:0048878 ! chemical homeostasis +created_by: mr +creation_date: 2014-07-11T20:58:24Z + +[Term] +id: GO:1903172 +name: cellular carbon dioxide homeostasis +namespace: biological_process +def: "Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell." [GO_REF:0000072, GOC:mr, GOC:TermGenie, PMID:16571594] +is_a: GO:0055082 ! cellular chemical homeostasis +is_a: GO:1903171 ! carbon dioxide homeostasis +created_by: mr +creation_date: 2014-07-11T20:58:30Z + +[Term] +id: GO:1903173 +name: fatty alcohol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving fatty alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:24036493] +synonym: "fatty alcohol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006066 ! alcohol metabolic process +is_a: GO:0006629 ! lipid metabolic process +created_by: tt +creation_date: 2014-07-14T01:51:41Z + +[Term] +id: GO:1903174 +name: fatty alcohol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of fatty alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:24036493] +synonym: "fatty alcohol breakdown" EXACT [GOC:TermGenie] +synonym: "fatty alcohol catabolism" EXACT [GOC:TermGenie] +synonym: "fatty alcohol degradation" EXACT [GOC:TermGenie] +is_a: GO:0016042 ! lipid catabolic process +is_a: GO:0046164 ! alcohol catabolic process +is_a: GO:1903173 ! fatty alcohol metabolic process +created_by: tt +creation_date: 2014-07-14T01:51:48Z + +[Term] +id: GO:1903175 +name: fatty alcohol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of fatty alcohol." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:24036493] +synonym: "fatty alcohol anabolism" EXACT [GOC:TermGenie] +synonym: "fatty alcohol biosynthesis" EXACT [GOC:TermGenie] +synonym: "fatty alcohol formation" EXACT [GOC:TermGenie] +synonym: "fatty alcohol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008610 ! lipid biosynthetic process +is_a: GO:0046165 ! alcohol biosynthetic process +is_a: GO:1903173 ! fatty alcohol metabolic process +created_by: tt +creation_date: 2014-07-14T01:51:54Z + +[Term] +id: GO:1903176 +name: regulation of tyrosine 3-monooxygenase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0032768 ! regulation of monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004511 ! tyrosine 3-monooxygenase activity +relationship: regulates GO:0004511 ! tyrosine 3-monooxygenase activity +created_by: bf +creation_date: 2014-07-14T10:39:09Z + +[Term] +id: GO:1903177 +name: negative regulation of tyrosine 3-monooxygenase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "down regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "downregulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of L-tyrosine hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine 3-hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine 3-monooxygenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0032769 ! negative regulation of monooxygenase activity +is_a: GO:1903176 ! regulation of tyrosine 3-monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004511 ! tyrosine 3-monooxygenase activity +relationship: negatively_regulates GO:0004511 ! tyrosine 3-monooxygenase activity +created_by: bf +creation_date: 2014-07-14T10:39:15Z + +[Term] +id: GO:1903178 +name: positive regulation of tyrosine 3-monooxygenase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19703902] +synonym: "activation of L-tyrosine hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" NARROW [GOC:TermGenie] +synonym: "activation of tyrosine 3-hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "activation of tyrosine 3-monooxygenase activity" NARROW [GOC:TermGenie] +synonym: "activation of tyrosine hydroxylase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of TH activity" EXACT [PMID:19703902] +synonym: "positive regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "stimulation of TH activity" EXACT [PMID:19703902] +synonym: "up regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "up regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [GOC:TermGenie] +synonym: "upregulation of tyrosine 3-hydroxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tyrosine 3-monooxygenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tyrosine hydroxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0032770 ! positive regulation of monooxygenase activity +is_a: GO:1903176 ! regulation of tyrosine 3-monooxygenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004511 ! tyrosine 3-monooxygenase activity +relationship: positively_regulates GO:0004511 ! tyrosine 3-monooxygenase activity +created_by: bf +creation_date: 2014-07-14T10:39:21Z + +[Term] +id: GO:1903179 +name: regulation of dopamine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "regulation of dopamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042053 ! regulation of dopamine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042416 ! dopamine biosynthetic process +relationship: regulates GO:0042416 ! dopamine biosynthetic process +created_by: bf +creation_date: 2014-07-14T12:17:41Z + +[Term] +id: GO:1903180 +name: negative regulation of dopamine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of dopamine anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine formation" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of dopamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045963 ! negative regulation of dopamine metabolic process +is_a: GO:1903179 ! regulation of dopamine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042416 ! dopamine biosynthetic process +relationship: negatively_regulates GO:0042416 ! dopamine biosynthetic process +created_by: bf +creation_date: 2014-07-14T12:17:47Z + +[Term] +id: GO:1903181 +name: positive regulation of dopamine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19703902] +synonym: "activation of dopamine anabolism" NARROW [GOC:TermGenie] +synonym: "activation of dopamine biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of dopamine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of dopamine formation" NARROW [GOC:TermGenie] +synonym: "activation of dopamine synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045964 ! positive regulation of dopamine metabolic process +is_a: GO:1903179 ! regulation of dopamine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042416 ! dopamine biosynthetic process +relationship: positively_regulates GO:0042416 ! dopamine biosynthetic process +created_by: bf +creation_date: 2014-07-14T12:17:53Z + +[Term] +id: GO:1903182 +name: regulation of SUMO transferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of SUMO ligase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of SMT3 conjugating enzyme" EXACT [GOC:TermGenie] +synonym: "regulation of SUMO conjugating enzyme activity" EXACT [GOC:TermGenie] +is_a: GO:0033233 ! regulation of protein sumoylation +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019789 ! SUMO transferase activity +relationship: regulates GO:0019789 ! SUMO transferase activity +created_by: bf +creation_date: 2014-07-14T14:01:40Z + +[Term] +id: GO:1903183 +name: negative regulation of SUMO transferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16731528] +synonym: "down regulation of SMT3 conjugating enzyme" EXACT [GOC:TermGenie] +synonym: "down regulation of SUMO conjugating enzyme activity" EXACT [GOC:TermGenie] +synonym: "down regulation of SUMO ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of SMT3 conjugating enzyme" EXACT [GOC:TermGenie] +synonym: "down-regulation of SUMO conjugating enzyme activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of SUMO ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of SMT3 conjugating enzyme" EXACT [GOC:TermGenie] +synonym: "downregulation of SUMO conjugating enzyme activity" EXACT [GOC:TermGenie] +synonym: "downregulation of SUMO ligase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of SMT3 conjugating enzyme" NARROW [GOC:TermGenie] +synonym: "inhibition of SUMO conjugating enzyme activity" NARROW [GOC:TermGenie] +synonym: "inhibition of SUMO ligase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of SMT3 conjugating enzyme" EXACT [GOC:TermGenie] +synonym: "negative regulation of SUMO conjugating enzyme activity" EXACT [GOC:TermGenie] +is_a: GO:0033234 ! negative regulation of protein sumoylation +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1903182 ! regulation of SUMO transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019789 ! SUMO transferase activity +relationship: negatively_regulates GO:0019789 ! SUMO transferase activity +created_by: bf +creation_date: 2014-07-14T14:01:46Z + +[Term] +id: GO:1903184 +name: L-dopa metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-dopa." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:8822146] +synonym: "L-dopa metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: bf +creation_date: 2014-07-14T15:06:00Z + +[Term] +id: GO:1903185 +name: L-dopa biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of L-dopa." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:8822146] +synonym: "L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "L-dopa formation" EXACT [GOC:TermGenie] +synonym: "L-dopa synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009073 ! aromatic amino acid family biosynthetic process +is_a: GO:0042398 ! cellular modified amino acid biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +is_a: GO:1903184 ! L-dopa metabolic process +created_by: bf +creation_date: 2014-07-14T15:06:06Z + +[Term] +id: GO:1903186 +name: regulation of vitellogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vitellogenesis." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19467235] +synonym: "regulation of yolk production" EXACT [GOC:TermGenie] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007296 ! vitellogenesis +relationship: regulates GO:0007296 ! vitellogenesis +created_by: mr +creation_date: 2014-07-14T19:28:00Z + +[Term] +id: GO:1903187 +name: negative regulation of vitellogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19467235] +synonym: "down regulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of yolk production" EXACT [GOC:TermGenie] +synonym: "down-regulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of yolk production" EXACT [GOC:TermGenie] +synonym: "downregulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of yolk production" EXACT [GOC:TermGenie] +synonym: "inhibition of vitellogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of yolk production" NARROW [GOC:TermGenie] +synonym: "negative regulation of yolk production" EXACT [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903186 ! regulation of vitellogenesis +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007296 ! vitellogenesis +relationship: negatively_regulates GO:0007296 ! vitellogenesis +created_by: mr +creation_date: 2014-07-14T19:28:06Z + +[Term] +id: GO:1903188 +name: positive regulation of vitellogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vitellogenesis." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19467235] +synonym: "activation of vitellogenesis" NARROW [GOC:TermGenie] +synonym: "activation of yolk production" NARROW [GOC:TermGenie] +synonym: "positive regulation of yolk production" EXACT [GOC:TermGenie] +synonym: "up regulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of yolk production" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of yolk production" EXACT [GOC:TermGenie] +synonym: "upregulation of vitellogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of yolk production" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903186 ! regulation of vitellogenesis +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007296 ! vitellogenesis +relationship: positively_regulates GO:0007296 ! vitellogenesis +created_by: mr +creation_date: 2014-07-14T19:28:12Z + +[Term] +id: GO:1903189 +name: glyoxal metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving glyoxal." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "glyoxal metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006081 ! cellular aldehyde metabolic process +created_by: bf +creation_date: 2014-07-15T10:11:45Z + +[Term] +id: GO:1903190 +name: glyoxal catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of glyoxal." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22523093, PMID:23651081] +synonym: "glyoxal breakdown" EXACT [GOC:TermGenie] +synonym: "glyoxal catabolism" EXACT [GOC:TermGenie] +synonym: "glyoxal degradation" EXACT [GOC:TermGenie] +is_a: GO:0046185 ! aldehyde catabolic process +is_a: GO:1903189 ! glyoxal metabolic process +created_by: bf +creation_date: 2014-07-15T10:11:51Z + +[Term] +id: GO:1903191 +name: glyoxal biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of glyoxal." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "glyoxal anabolism" EXACT [GOC:TermGenie] +synonym: "glyoxal biosynthesis" EXACT [GOC:TermGenie] +synonym: "glyoxal formation" EXACT [GOC:TermGenie] +synonym: "glyoxal synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046184 ! aldehyde biosynthetic process +is_a: GO:1903189 ! glyoxal metabolic process +created_by: bf +creation_date: 2014-07-15T10:11:57Z + +[Term] +id: GO:1903192 +name: sesquarterpene metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving sesquarterpene." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21627333] +synonym: "sesquarterpene metabolism" EXACT [GOC:TermGenie] +is_a: GO:0042214 ! terpene metabolic process +created_by: tt +creation_date: 2014-07-16T17:04:47Z + +[Term] +id: GO:1903193 +name: sesquarterpene biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of sesquarterpene." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:21627333] +synonym: "sesquarterpene anabolism" EXACT [GOC:TermGenie] +synonym: "sesquarterpene biosynthesis" EXACT [GOC:TermGenie] +synonym: "sesquarterpene formation" EXACT [GOC:TermGenie] +synonym: "sesquarterpene synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046246 ! terpene biosynthetic process +is_a: GO:1903192 ! sesquarterpene metabolic process +created_by: tt +creation_date: 2014-07-16T17:04:53Z + +[Term] +id: GO:1903195 +name: regulation of L-dopa biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903185 ! L-dopa biosynthetic process +relationship: regulates GO:1903185 ! L-dopa biosynthetic process +created_by: bf +creation_date: 2014-07-21T09:12:37Z + +[Term] +id: GO:1903196 +name: negative regulation of L-dopa biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "down regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of L-dopa anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of L-dopa biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of L-dopa biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of L-dopa formation" NARROW [GOC:TermGenie] +synonym: "inhibition of L-dopa synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +is_a: GO:1903195 ! regulation of L-dopa biosynthetic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903185 ! L-dopa biosynthetic process +relationship: negatively_regulates GO:1903185 ! L-dopa biosynthetic process +created_by: bf +creation_date: 2014-07-21T09:12:44Z + +[Term] +id: GO:1903197 +name: positive regulation of L-dopa biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16731528] +synonym: "activation of L-dopa anabolism" NARROW [GOC:TermGenie] +synonym: "activation of L-dopa biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of L-dopa biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of L-dopa formation" NARROW [GOC:TermGenie] +synonym: "activation of L-dopa synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa formation" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa synthesis" EXACT [GOC:TermGenie] +is_a: GO:1903195 ! regulation of L-dopa biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903185 ! L-dopa biosynthetic process +relationship: positively_regulates GO:1903185 ! L-dopa biosynthetic process +created_by: bf +creation_date: 2014-07-21T09:12:49Z + +[Term] +id: GO:1903198 +name: regulation of L-dopa decarboxylase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036468 ! L-dopa decarboxylase activity +relationship: regulates GO:0036468 ! L-dopa decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:32:31Z + +[Term] +id: GO:1903199 +name: negative regulation of L-dopa decarboxylase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 4-dihydroxyl-L-phenylalanine decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DDC activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DOPA decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of L-dopa decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051350 ! negative regulation of lyase activity +is_a: GO:1903198 ! regulation of L-dopa decarboxylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036468 ! L-dopa decarboxylase activity +relationship: negatively_regulates GO:0036468 ! L-dopa decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:32:37Z + +[Term] +id: GO:1903200 +name: positive regulation of L-dopa decarboxylase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19703902] +synonym: "activation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "activation of DDC activity" NARROW [GOC:TermGenie] +synonym: "activation of DOPA decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-dopa decarboxylase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DDC activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DOPA decarboxylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-dopa decarboxylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051349 ! positive regulation of lyase activity +is_a: GO:1903198 ! regulation of L-dopa decarboxylase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036468 ! L-dopa decarboxylase activity +relationship: positively_regulates GO:0036468 ! L-dopa decarboxylase activity +created_by: bf +creation_date: 2014-07-21T09:32:43Z + +[Term] +id: GO:1903201 +name: regulation of oxidative stress-induced cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of cell death in response to oxidative stress" EXACT [GOC:bf] +is_a: GO:0010941 ! regulation of cell death +is_a: GO:1900407 ! regulation of cellular response to oxidative stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036473 ! cell death in response to oxidative stress +relationship: regulates GO:0036473 ! cell death in response to oxidative stress +created_by: bf +creation_date: 2014-07-21T16:10:30Z + +[Term] +id: GO:1903202 +name: negative regulation of oxidative stress-induced cell death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "down regulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cell death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell death in response to oxidative stress" EXACT [GOC:bf] +synonym: "protection against oxidative stress-induced cell death" RELATED [GOC:bf] +is_a: GO:0060548 ! negative regulation of cell death +is_a: GO:1900408 ! negative regulation of cellular response to oxidative stress +is_a: GO:1903201 ! regulation of oxidative stress-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036473 ! cell death in response to oxidative stress +relationship: negatively_regulates GO:0036473 ! cell death in response to oxidative stress +created_by: bf +creation_date: 2014-07-21T16:10:36Z + +[Term] +id: GO:1903203 +name: regulation of oxidative stress-induced neuron death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of neuron death in response to oxidative stress" EXACT [GOC:bf] +synonym: "regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:1901214 ! regulation of neuron death +is_a: GO:1903201 ! regulation of oxidative stress-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036475 ! neuron death in response to oxidative stress +relationship: regulates GO:0036475 ! neuron death in response to oxidative stress +created_by: bf +creation_date: 2014-07-21T16:17:30Z + +[Term] +id: GO:1903204 +name: negative regulation of oxidative stress-induced neuron death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "down regulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down regulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +synonym: "inhibition of neuron death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "inhibition of neuronal cell death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "inhibition of oxidative stress-induced neuron death" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "neuronal protection under oxidative stress" RELATED [GOC:bf] +synonym: "neuroprotection against oxidative stress" RELATED [GOC:bf] +is_a: GO:1901215 ! negative regulation of neuron death +is_a: GO:1903202 ! negative regulation of oxidative stress-induced cell death +is_a: GO:1903203 ! regulation of oxidative stress-induced neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036475 ! neuron death in response to oxidative stress +relationship: negatively_regulates GO:0036475 ! neuron death in response to oxidative stress +created_by: bf +creation_date: 2014-07-21T16:17:36Z + +[Term] +id: GO:1903205 +name: regulation of hydrogen peroxide-induced cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "protection against hydrogen peroxide-mediated cell death" RELATED [GOC:bf] +synonym: "regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "regulation of cell death in response to hydrogen peroxide" EXACT [GOC:bf] +synonym: "regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +is_a: GO:1901031 ! regulation of response to reactive oxygen species +is_a: GO:1903201 ! regulation of oxidative stress-induced cell death +is_a: GO:2001038 ! regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036474 ! cell death in response to hydrogen peroxide +relationship: regulates GO:0036474 ! cell death in response to hydrogen peroxide +created_by: bf +creation_date: 2014-07-21T16:21:47Z + +[Term] +id: GO:1903206 +name: negative regulation of hydrogen peroxide-induced cell death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:14749723, PMID:24252804] +synonym: "down regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down regulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "downregulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "downregulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "inhibition of cell death in response to H2O2" NARROW [GOC:TermGenie] +synonym: "inhibition of cell death in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "negative regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell death in response to hydrogen peroxide" EXACT [GOC:bf] +synonym: "negative regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "protection against H2O2-induced cell death" RELATED [GOC:bf] +synonym: "protection against hydrogen peroxide-induced cell death" RELATED [GOC:bf] +is_a: GO:1901032 ! negative regulation of response to reactive oxygen species +is_a: GO:1903202 ! negative regulation of oxidative stress-induced cell death +is_a: GO:1903205 ! regulation of hydrogen peroxide-induced cell death +is_a: GO:2001039 ! negative regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036474 ! cell death in response to hydrogen peroxide +relationship: negatively_regulates GO:0036474 ! cell death in response to hydrogen peroxide +created_by: bf +creation_date: 2014-07-21T16:21:53Z + +[Term] +id: GO:1903207 +name: regulation of hydrogen peroxide-induced neuron death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of neuron death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "regulation of neuron death in response to hydrogen peroxide" EXACT [GOC:bf] +synonym: "regulation of neuronal cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +is_a: GO:1903203 ! regulation of oxidative stress-induced neuron death +is_a: GO:1903205 ! regulation of hydrogen peroxide-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036476 ! neuron death in response to hydrogen peroxide +relationship: regulates GO:0036476 ! neuron death in response to hydrogen peroxide +created_by: bf +creation_date: 2014-07-21T16:27:05Z + +[Term] +id: GO:1903208 +name: negative regulation of hydrogen peroxide-induced neuron death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "down regulation of hydrogen peroxide-induced neuron death" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down regulation of neuronal cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen peroxide-induced neuron death" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuronal cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen peroxide-induced neuron death" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "downregulation of neuronal cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "inhibition of hydrogen peroxide-induced neuron death" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron death in response to H2O2" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron death in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "inhibition of neuronal cell death in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuron death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuron death in response to hydrogen peroxide" EXACT [GOC:bf] +synonym: "negative regulation of neuronal cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "neuroprotection against H2O2-induced cell death" RELATED [GOC:bf] +synonym: "neuroprotection against hydrogen peroxide" RELATED [GOC:bf] +synonym: "protection against H2O2-induced neuron death" RELATED [GOC:bf] +synonym: "protection against hydrogen peroxide-induced neuron death" RELATED [GOC:bf] +is_a: GO:1903204 ! negative regulation of oxidative stress-induced neuron death +is_a: GO:1903206 ! negative regulation of hydrogen peroxide-induced cell death +is_a: GO:1903207 ! regulation of hydrogen peroxide-induced neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036476 ! neuron death in response to hydrogen peroxide +relationship: negatively_regulates GO:0036476 ! neuron death in response to hydrogen peroxide +created_by: bf +creation_date: 2014-07-21T16:27:11Z + +[Term] +id: GO:1903209 +name: positive regulation of oxidative stress-induced cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:20969476] +synonym: "activation of cell death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "enhancement of oxidative stress-induced cell death" NARROW [] +synonym: "positive regulation of cell death in response to oxidative stress" EXACT [] +synonym: "up regulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of cell death in response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:0010942 ! positive regulation of cell death +is_a: GO:1900409 ! positive regulation of cellular response to oxidative stress +is_a: GO:1903201 ! regulation of oxidative stress-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036473 ! cell death in response to oxidative stress +relationship: positively_regulates GO:0036473 ! cell death in response to oxidative stress +created_by: bf +creation_date: 2014-07-22T09:32:19Z + +[Term] +id: GO:1903210 +name: glomerular visceral epithelial cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a glomerular visceral epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:23515840] +synonym: "glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "podocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2014-07-23T17:07:55Z + +[Term] +id: GO:1903211 +name: mitotic recombination involved in replication fork processing +namespace: biological_process +def: "Any mitotic recombination that is involved in replication fork processing." [GO_REF:0000060, GOC:mah, GOC:TermGenie, PMID:23093942] +synonym: "mitotic recombination involved in collapsed replication fork processing" EXACT [GOC:TermGenie] +synonym: "mitotic recombination involved in recovery from replication fork arrest" EXACT [GOC:TermGenie] +synonym: "mitotic recombination involved in recovery from replication fork stalling" EXACT [GOC:TermGenie] +synonym: "mitotic recombination involved in replication fork restart" RELATED [GOC:TermGenie] +synonym: "mitotic recombination involved in replication restart" RELATED [GOC:TermGenie] +is_a: GO:0006312 ! mitotic recombination +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0006312 ! mitotic recombination +intersection_of: part_of GO:1990426 ! mitotic recombination-dependent replication fork processing +relationship: part_of GO:1990426 ! mitotic recombination-dependent replication fork processing +created_by: mah +creation_date: 2014-07-24T09:33:40Z + +[Term] +id: GO:1903212 +name: protein localization to mating-type region heterochromatin +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin." [GO_REF:0000087, GOC:TermGenie, PMID:18761674] +synonym: "protein localisation in mating-type region heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localisation to mating-type region heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localization in mating-type region heterochromatin" EXACT [GOC:TermGenie] +is_a: GO:0097355 ! protein localization to heterochromatin +created_by: mah +creation_date: 2014-07-24T09:38:12Z + +[Term] +id: GO:1903213 +name: protein localization to subtelomeric heterochromatin +namespace: biological_process +alt_id: GO:1990152 +def: "A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin." [GO_REF:0000087, GOC:TermGenie, PMID:21300781, SO:0001997] +synonym: "protein localisation in subtelomeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localisation to subtelomeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localisation to telomeric heterochromatin" RELATED [GOC:mah] +synonym: "protein localization in subtelomeric heterochromatin" EXACT [GOC:TermGenie] +synonym: "protein localization to telomeric heterochromatin" RELATED [] +is_a: GO:0034504 ! protein localization to nucleus +is_a: GO:0070198 ! protein localization to chromosome, telomeric region +is_a: GO:0097355 ! protein localization to heterochromatin +created_by: mah +creation_date: 2013-07-31T15:04:26Z + +[Term] +id: GO:1903214 +name: regulation of protein targeting to mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +is_a: GO:0010821 ! regulation of mitochondrion organization +is_a: GO:1903533 ! regulation of protein targeting +is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006626 ! protein targeting to mitochondrion +relationship: regulates GO:0006626 ! protein targeting to mitochondrion +created_by: bf +creation_date: 2014-07-24T10:17:13Z + +[Term] +id: GO:1903215 +name: negative regulation of protein targeting to mitochondrion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995] +synonym: "down regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "down regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "down regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "down regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "down regulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "down-regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "downregulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "downregulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "downregulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "inhibition of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "inhibition of protein import into mitochondrion" NARROW [GOC:TermGenie] +synonym: "inhibition of protein targeting to mitochondria" NARROW [GOC:TermGenie] +synonym: "inhibition of protein targeting to mitochondrion" NARROW [GOC:TermGenie] +synonym: "inhibition of protein-mitochondrial targeting" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1903214 ! regulation of protein targeting to mitochondrion +is_a: GO:1903748 ! negative regulation of establishment of protein localization to mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006626 ! protein targeting to mitochondrion +relationship: negatively_regulates GO:0006626 ! protein targeting to mitochondrion +created_by: bf +creation_date: 2014-07-24T10:17:19Z + +[Term] +id: GO:1903216 +name: regulation of protein processing involved in protein targeting to mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995] +synonym: "regulation of mitochondrial processing" BROAD [GOC:TermGenie] +synonym: "regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0070613 ! regulation of protein processing +is_a: GO:1903214 ! regulation of protein targeting to mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion +relationship: regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion +created_by: bf +creation_date: 2014-07-24T10:20:54Z + +[Term] +id: GO:1903217 +name: negative regulation of protein processing involved in protein targeting to mitochondrion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21370995] +synonym: "down regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +synonym: "down regulation of protein processing involved in protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein processing involved in protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +synonym: "downregulation of protein processing involved in protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +synonym: "inhibition of protein processing involved in protein targeting to mitochondrion" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial protein processing during import" RELATED [GOC:TermGenie] +is_a: GO:0010955 ! negative regulation of protein processing +is_a: GO:1903215 ! negative regulation of protein targeting to mitochondrion +is_a: GO:1903216 ! regulation of protein processing involved in protein targeting to mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion +relationship: negatively_regulates GO:0006627 ! protein processing involved in protein targeting to mitochondrion +created_by: bf +creation_date: 2014-07-24T10:21:00Z + +[Term] +id: GO:1903218 +name: regulation of malate dehydrogenase (decarboxylating) (NADP+) activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity." [GO_REF:0000059, GOC:sart, GOC:TermGenie, PMID:12398416] +synonym: "regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +relationship: regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +created_by: sart +creation_date: 2014-07-24T11:17:22Z + +[Term] +id: GO:1903219 +name: negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity." [GO_REF:0000059, GOC:sart, GOC:TermGenie, PMID:12398416] +synonym: "down regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "down regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "down regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "down regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "down regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "down regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "down-regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "down-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "down-regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "down-regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "downregulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "downregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "downregulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "downregulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "downregulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "downregulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "inhibition of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "inhibition of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" NARROW [GOC:TermGenie] +synonym: "inhibition of L-malate:NADP oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of malate dehydrogenase (decarboxylating) (NADP+) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of malate dehydrogenase (decarboxylating, NADP)" NARROW [GOC:TermGenie] +synonym: "inhibition of malate dehydrogenase (NADP, decarboxylating)" NARROW [GOC:TermGenie] +synonym: "inhibition of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "inhibition of NADP-malic enzyme activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NADP-specific malate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "negative regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "negative regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "negative regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "negative regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1903218 ! regulation of malate dehydrogenase (decarboxylating) (NADP+) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +relationship: negatively_regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +created_by: sart +creation_date: 2014-07-24T11:17:28Z + +[Term] +id: GO:1903220 +name: positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity." [GO_REF:0000059, GOC:sart, GOC:TermGenie, PMID:12398416] +synonym: "activation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "activation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" NARROW [GOC:TermGenie] +synonym: "activation of L-malate:NADP oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of malate dehydrogenase (decarboxylating) (NADP+) activity" NARROW [GOC:TermGenie] +synonym: "activation of malate dehydrogenase (decarboxylating, NADP)" NARROW [GOC:TermGenie] +synonym: "activation of malate dehydrogenase (NADP, decarboxylating)" NARROW [GOC:TermGenie] +synonym: "activation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "activation of NADP-malic enzyme activity" NARROW [GOC:TermGenie] +synonym: "activation of NADP-specific malate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "positive regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "up regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "up regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "up regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "up regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "up regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "up regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "up-regulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +synonym: "upregulation of 'malic' enzyme" RELATED [GOC:TermGenie] +synonym: "upregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [GOC:TermGenie] +synonym: "upregulation of L-malate:NADP oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of malate dehydrogenase (decarboxylating) (NADP+) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of malate dehydrogenase (decarboxylating, NADP)" EXACT [GOC:TermGenie] +synonym: "upregulation of malate dehydrogenase (NADP, decarboxylating)" EXACT [GOC:TermGenie] +synonym: "upregulation of NADP-linked decarboxylating malic enzyme" RELATED [GOC:TermGenie] +synonym: "upregulation of NADP-malic enzyme activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NADP-specific malate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NADP-specific malic enzyme" RELATED [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1903218 ! regulation of malate dehydrogenase (decarboxylating) (NADP+) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +relationship: positively_regulates GO:0004473 ! malate dehydrogenase (decarboxylating) (NADP+) activity +created_by: sart +creation_date: 2014-07-24T11:17:34Z + +[Term] +id: GO:1903221 +name: regulation of mitotic recombination involved in replication fork processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences." [GO_REF:0000058, GOC:TermGenie, PMID:23093942] +synonym: "prevention of genomic instability induced by DNA replication fork arrest" RELATED [PMID:23093942] +synonym: "regulation of mitotic recombination involved in collapsed replication fork processing" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic recombination involved in recovery from replication fork arrest" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic recombination involved in recovery from replication fork stalling" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic recombination involved in replication fork restart" RELATED [GOC:TermGenie] +synonym: "regulation of mitotic recombination involved in replication restart" RELATED [GOC:TermGenie] +is_a: GO:0000019 ! regulation of mitotic recombination +is_a: GO:1903463 ! regulation of mitotic cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903211 ! mitotic recombination involved in replication fork processing +relationship: regulates GO:1903211 ! mitotic recombination involved in replication fork processing +created_by: mah +creation_date: 2014-07-24T13:30:21Z + +[Term] +id: GO:1903222 +name: quinolinic acid transmembrane transport +namespace: biological_process +def: "The process in which quinolinic acid is transported across a membrane." [GO_REF:0000069, GOC:di, GOC:TermGenie, PMID:23457190] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0071705 ! nitrogen compound transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: di +creation_date: 2014-07-26T07:29:07Z + +[Term] +id: GO:1903223 +name: positive regulation of oxidative stress-induced neuron death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23858059] +synonym: "activation of neuron death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "activation of neuronal cell death in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "activation of oxidative stress-induced neuron death" NARROW [GOC:TermGenie] +synonym: "positive regulation of neuron death in response to oxidative stress" EXACT [GOC:bf] +synonym: "positive regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "sensitization of neuron to oxidative stress-induced cell death" RELATED [PMID:23858059] +synonym: "up regulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +synonym: "upregulation of neuron death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of neuronal cell death in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidative stress-induced neuron death" EXACT [GOC:TermGenie] +is_a: GO:1901216 ! positive regulation of neuron death +is_a: GO:1903203 ! regulation of oxidative stress-induced neuron death +is_a: GO:1903209 ! positive regulation of oxidative stress-induced cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036475 ! neuron death in response to oxidative stress +relationship: positively_regulates GO:0036475 ! neuron death in response to oxidative stress +created_by: bf +creation_date: 2014-07-29T08:51:52Z + +[Term] +id: GO:1903224 +name: regulation of endodermal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] +synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035987 ! endodermal cell differentiation +relationship: regulates GO:0035987 ! endodermal cell differentiation +created_by: als +creation_date: 2014-07-29T13:22:35Z + +[Term] +id: GO:1903225 +name: negative regulation of endodermal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] +synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of endoderm cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of endodermal cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1903224 ! regulation of endodermal cell differentiation +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035987 ! endodermal cell differentiation +relationship: negatively_regulates GO:0035987 ! endodermal cell differentiation +created_by: als +creation_date: 2014-07-29T13:22:41Z + +[Term] +id: GO:1903226 +name: positive regulation of endodermal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] +synonym: "activation of endoderm cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of endodermal cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1903224 ! regulation of endodermal cell differentiation +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035987 ! endodermal cell differentiation +relationship: positively_regulates GO:0035987 ! endodermal cell differentiation +created_by: als +creation_date: 2014-07-29T13:22:47Z + +[Term] +id: GO:1903227 +name: xanthosine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving xanthosine." [GO_REF:0000068, GOC:TermGenie, PMID:7007809, PMID:7559336] +synonym: "xanthosine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046128 ! purine ribonucleoside metabolic process +created_by: jl +creation_date: 2014-07-31T09:21:46Z + +[Term] +id: GO:1903228 +name: xanthosine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of xanthosine." [GO_REF:0000068, GOC:TermGenie, PMID:7007809, PMID:7559336] +synonym: "xanthosine breakdown" EXACT [GOC:TermGenie] +synonym: "xanthosine catabolism" EXACT [GOC:TermGenie] +synonym: "xanthosine degradation" EXACT [GOC:TermGenie] +is_a: GO:0046130 ! purine ribonucleoside catabolic process +is_a: GO:1903227 ! xanthosine metabolic process +created_by: jl +creation_date: 2014-07-31T09:21:52Z + +[Term] +id: GO:1903229 +name: xanthosine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of xanthosine." [GO_REF:0000068, GOC:TermGenie, PMID:7007809, PMID:7559336] +synonym: "xanthosine anabolism" EXACT [GOC:TermGenie] +synonym: "xanthosine biosynthesis" EXACT [GOC:TermGenie] +synonym: "xanthosine formation" EXACT [GOC:TermGenie] +synonym: "xanthosine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046129 ! purine ribonucleoside biosynthetic process +is_a: GO:1903227 ! xanthosine metabolic process +created_by: jl +creation_date: 2014-07-31T09:21:58Z + +[Term] +id: GO:1903230 +name: obsolete miRNA binding involved in posttranscriptional gene silencing +namespace: molecular_function +def: "OBSOLETE. Any miRNA binding that is involved in posttranscriptional gene silencing." [GO_REF:0000061, GOC:BHF, GOC:jl, GOC:TermGenie] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "microRNA binding involved in cosuppression" RELATED [GOC:TermGenie] +synonym: "microRNA binding involved in post-transcriptional gene silencing" EXACT [GOC:TermGenie] +synonym: "microRNA binding involved in posttranscriptional gene silencing" EXACT [GOC:TermGenie] +synonym: "microRNA binding involved in PTGS" EXACT [GOC:TermGenie] +synonym: "microRNA binding involved in quelling" EXACT [GOC:TermGenie] +synonym: "miRNA binding involved in cosuppression" RELATED [GOC:TermGenie] +synonym: "miRNA binding involved in post-transcriptional gene silencing" EXACT [GOC:TermGenie] +synonym: "miRNA binding involved in posttranscriptional gene silencing" EXACT [] +synonym: "miRNA binding involved in PTGS" EXACT [GOC:TermGenie] +synonym: "miRNA binding involved in quelling" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: jl +creation_date: 2014-07-31T10:22:18Z + +[Term] +id: GO:1903231 +name: mRNA binding involved in posttranscriptional gene silencing +namespace: molecular_function +def: "Any mRNA binding that is involved in posttranscriptional gene silencing." [GO_REF:0000061, GOC:BHF, GOC:BHF_miRNA, GOC:jl, GOC:TermGenie] +synonym: "mRNA binding involved in cosuppression" RELATED [GOC:TermGenie] +synonym: "mRNA binding involved in post-transcriptional gene silencing" EXACT [GOC:TermGenie] +synonym: "mRNA binding involved in PTGS" EXACT [GOC:TermGenie] +synonym: "mRNA binding involved in quelling" EXACT [GOC:TermGenie] +is_a: GO:0003729 ! mRNA binding +is_a: GO:0150100 ! RNA binding involved in posttranscriptional gene silencing +intersection_of: GO:0003729 ! mRNA binding +intersection_of: part_of GO:0016441 ! posttranscriptional gene silencing +created_by: jl +creation_date: 2014-07-31T10:30:43Z + +[Term] +id: GO:1903232 +name: melanosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22511774] +synonym: "melanosome formation" EXACT [GOC:TermGenie] +is_a: GO:0032438 ! melanosome organization +is_a: GO:0070925 ! organelle assembly +created_by: bf +creation_date: 2014-07-31T10:41:38Z + +[Term] +id: GO:1903233 +name: regulation of calcium ion-dependent exocytosis of neurotransmitter +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP) +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +relationship: regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +created_by: pad +creation_date: 2014-07-31T11:54:33Z + +[Term] +id: GO:1903234 +name: negative regulation of calcium ion-dependent exocytosis of neurotransmitter +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP) +synonym: "down regulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion-dependent exocytosis of neurotransmitter" NARROW [GOC:TermGenie] +is_a: GO:0045955 ! negative regulation of calcium ion-dependent exocytosis +is_a: GO:1903233 ! regulation of calcium ion-dependent exocytosis of neurotransmitter +is_a: GO:2000301 ! negative regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +relationship: negatively_regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +created_by: pad +creation_date: 2014-07-31T11:54:40Z + +[Term] +id: GO:1903235 +name: positive regulation of calcium ion-dependent exocytosis of neurotransmitter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP) +synonym: "activation of calcium ion-dependent exocytosis of neurotransmitter" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion-dependent exocytosis of neurotransmitter" EXACT [GOC:TermGenie] +is_a: GO:0045956 ! positive regulation of calcium ion-dependent exocytosis +is_a: GO:1903233 ! regulation of calcium ion-dependent exocytosis of neurotransmitter +is_a: GO:2000302 ! positive regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +relationship: positively_regulates GO:0048791 ! calcium ion-regulated exocytosis of neurotransmitter +created_by: pad +creation_date: 2014-07-31T11:54:46Z + +[Term] +id: GO:1903236 +name: regulation of leukocyte tethering or rolling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18308860] +is_a: GO:0002691 ! regulation of cellular extravasation +is_a: GO:1904994 ! regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050901 ! leukocyte tethering or rolling +relationship: regulates GO:0050901 ! leukocyte tethering or rolling +created_by: als +creation_date: 2014-07-31T13:07:48Z + +[Term] +id: GO:1903237 +name: negative regulation of leukocyte tethering or rolling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18308860] +synonym: "down regulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +synonym: "inhibition of leukocyte tethering or rolling" NARROW [GOC:TermGenie] +is_a: GO:0002692 ! negative regulation of cellular extravasation +is_a: GO:1903236 ! regulation of leukocyte tethering or rolling +is_a: GO:1904995 ! negative regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050901 ! leukocyte tethering or rolling +relationship: negatively_regulates GO:0050901 ! leukocyte tethering or rolling +created_by: als +creation_date: 2014-07-31T13:07:55Z + +[Term] +id: GO:1903238 +name: positive regulation of leukocyte tethering or rolling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18308860] +synonym: "activation of leukocyte tethering or rolling" NARROW [GOC:TermGenie] +synonym: "up regulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte tethering or rolling" EXACT [GOC:TermGenie] +is_a: GO:0002693 ! positive regulation of cellular extravasation +is_a: GO:1903236 ! regulation of leukocyte tethering or rolling +is_a: GO:1904996 ! positive regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050901 ! leukocyte tethering or rolling +relationship: positively_regulates GO:0050901 ! leukocyte tethering or rolling +created_by: als +creation_date: 2014-07-31T13:08:01Z + +[Term] +id: GO:1903239 +name: obsolete regulation of positive regulation of the force of heart contraction by chemical signal +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17242280] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of positive regulation of the force of heart contraction by chemical signal" EXACT [] +synonym: "regulation of positive regulation of the force of heart muscle contraction by chemical signal" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rl +creation_date: 2014-07-31T17:00:17Z + +[Term] +id: GO:1903240 +name: obsolete negative regulation of positive regulation of the force of heart contraction by chemical signal +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17242280] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of positive regulation of the force of heart contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "down regulation of positive regulation of the force of heart muscle contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive regulation of the force of heart contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "down-regulation of positive regulation of the force of heart muscle contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "downregulation of positive regulation of the force of heart contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "downregulation of positive regulation of the force of heart muscle contraction by chemical signal" EXACT [GOC:TermGenie] +synonym: "inhibition of positive regulation of the force of heart contraction by chemical signal" NARROW [GOC:TermGenie] +synonym: "inhibition of positive regulation of the force of heart muscle contraction by chemical signal" NARROW [GOC:TermGenie] +synonym: "negative regulation of positive regulation of the force of heart contraction by chemical signal" EXACT [] +synonym: "negative regulation of positive regulation of the force of heart muscle contraction by chemical signal" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rl +creation_date: 2014-07-31T17:00:23Z + +[Term] +id: GO:1903241 +name: U2-type prespliceosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome." [GO_REF:0000079, GOC:TermGenie, PMID:12374752] +synonym: "GT-AG prespliceosome assembly" NARROW [GOC:TermGenie] +synonym: "GT-AG prespliceosome formation" NARROW [GOC:TermGenie] +synonym: "major prespliceosome assembly" EXACT [GOC:TermGenie] +synonym: "major prespliceosome formation" EXACT [GOC:TermGenie] +synonym: "mammalian U2-type spliceosomal complex A assembly" NARROW [GOC:TermGenie] +synonym: "mammalian U2-type spliceosomal complex A formation" NARROW [GOC:TermGenie] +synonym: "U2-type prespliceosome formation" EXACT [GOC:TermGenie] +synonym: "yeast U2-type spliceosomal complex B assembly" NARROW [GOC:TermGenie] +synonym: "yeast U2-type spliceosomal complex B formation" NARROW [GOC:TermGenie] +is_a: GO:0000245 ! spliceosomal complex assembly +created_by: mah +creation_date: 2014-08-01T14:33:45Z + +[Term] +id: GO:1903242 +name: regulation of cardiac muscle hypertrophy in response to stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19287093] +is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy +is_a: GO:0010612 ! regulation of cardiac muscle adaptation +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +relationship: regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +created_by: rl +creation_date: 2014-08-01T16:31:36Z + +[Term] +id: GO:1903243 +name: negative regulation of cardiac muscle hypertrophy in response to stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19287093] +synonym: "down regulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac muscle hypertrophy in response to stress" NARROW [GOC:TermGenie] +is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy +is_a: GO:0010616 ! negative regulation of cardiac muscle adaptation +is_a: GO:1903242 ! regulation of cardiac muscle hypertrophy in response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +relationship: negatively_regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +created_by: rl +creation_date: 2014-08-01T16:31:42Z + +[Term] +id: GO:1903244 +name: positive regulation of cardiac muscle hypertrophy in response to stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19287093] +synonym: "activation of cardiac muscle hypertrophy in response to stress" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac muscle hypertrophy in response to stress" EXACT [GOC:TermGenie] +is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy +is_a: GO:0010615 ! positive regulation of cardiac muscle adaptation +is_a: GO:1903242 ! regulation of cardiac muscle hypertrophy in response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +relationship: positively_regulates GO:0014898 ! cardiac muscle hypertrophy in response to stress +created_by: rl +creation_date: 2014-08-01T16:31:48Z + +[Term] +id: GO:1903245 +name: obsolete regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:17242280] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: rl +creation_date: 2014-08-04T11:53:54Z + +[Term] +id: GO:1903246 +name: obsolete negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:17242280] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "down regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "down regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "down-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "down-regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "downregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "downregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "downregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "downregulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "inhibition of adrenergic receptor signalling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "inhibition of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "inhibition of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "inhibition of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "negative regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "negative regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: rl +creation_date: 2014-08-04T11:54:00Z + +[Term] +id: GO:1903247 +name: obsolete positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:17242280] +comment: This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation. +synonym: "activation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "activation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "activation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "activation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "activation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "positive regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "positive regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "up regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "up-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "up-regulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of activation of funny current by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "upregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "upregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate" NARROW [GOC:TermGenie] +synonym: "upregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate" EXACT [GOC:TermGenie] +synonym: "upregulation of If activation by beta-adrenergic receptor signaling pathway" RELATED [GOC:TermGenie] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14733 xsd:anyURI +is_obsolete: true +created_by: rl +creation_date: 2014-08-04T11:54:06Z + +[Term] +id: GO:1903248 +name: regulation of citrulline biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of citrulline biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19278978] +synonym: "regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "regulation of citrulline synthesis" EXACT [GOC:TermGenie] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019240 ! citrulline biosynthetic process +relationship: regulates GO:0019240 ! citrulline biosynthetic process +created_by: rl +creation_date: 2014-08-04T15:24:34Z + +[Term] +id: GO:1903249 +name: negative regulation of citrulline biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19278978] +synonym: "down regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "down regulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "downregulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of citrulline anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of citrulline biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of citrulline biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of citrulline formation" NARROW [GOC:TermGenie] +synonym: "inhibition of citrulline synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of citrulline synthesis" EXACT [GOC:TermGenie] +is_a: GO:1903248 ! regulation of citrulline biosynthetic process +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019240 ! citrulline biosynthetic process +relationship: negatively_regulates GO:0019240 ! citrulline biosynthetic process +created_by: rl +creation_date: 2014-08-04T15:24:46Z + +[Term] +id: GO:1903250 +name: positive regulation of citrulline biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19278978] +synonym: "activation of citrulline anabolism" NARROW [GOC:TermGenie] +synonym: "activation of citrulline biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of citrulline biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of citrulline formation" NARROW [GOC:TermGenie] +synonym: "activation of citrulline synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline formation" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline synthesis" EXACT [GOC:TermGenie] +is_a: GO:1903248 ! regulation of citrulline biosynthetic process +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019240 ! citrulline biosynthetic process +relationship: positively_regulates GO:0019240 ! citrulline biosynthetic process +created_by: rl +creation_date: 2014-08-04T15:24:52Z + +[Term] +id: GO:1903251 +name: multi-ciliated epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell." [GO_REF:0000086, GOC:sp, GOC:TermGenie, PMID:22231168, PMID:24934224] +synonym: "multiciliate cell differentiation" BROAD [] +is_a: GO:0030855 ! epithelial cell differentiation +created_by: tb +creation_date: 2014-08-05T19:21:21Z + +[Term] +id: GO:1903252 +name: hercynylcysteine sulfoxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hercynylcysteine sulfoxide." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "hercynylcysteine sulfoxide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: mah +creation_date: 2014-08-06T09:13:50Z + +[Term] +id: GO:1903253 +name: hercynylcysteine sulfoxide biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "hercynylcysteine sulfoxide anabolism" EXACT [GOC:TermGenie] +synonym: "hercynylcysteine sulfoxide biosynthesis" EXACT [GOC:TermGenie] +synonym: "hercynylcysteine sulfoxide formation" EXACT [GOC:TermGenie] +synonym: "hercynylcysteine sulfoxide synthesis" EXACT [GOC:TermGenie] +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:0052703 ! cellular modified histidine biosynthetic process +is_a: GO:1903252 ! hercynylcysteine sulfoxide metabolic process +created_by: mah +creation_date: 2014-08-06T09:14:00Z + +[Term] +id: GO:1903254 +name: hercynylselenocysteine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving hercynylselenocysteine." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "hercynylselenocysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0001887 ! selenium compound metabolic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: mah +creation_date: 2014-08-06T09:14:08Z + +[Term] +id: GO:1903255 +name: hercynylselenocysteine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of hercynylselenocysteine." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "hercynylselenocysteine anabolism" EXACT [GOC:TermGenie] +synonym: "hercynylselenocysteine biosynthesis" EXACT [GOC:TermGenie] +synonym: "hercynylselenocysteine formation" EXACT [GOC:TermGenie] +synonym: "hercynylselenocysteine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0052703 ! cellular modified histidine biosynthetic process +is_a: GO:1903254 ! hercynylselenocysteine metabolic process +created_by: mah +creation_date: 2014-08-06T09:14:16Z + +[Term] +id: GO:1903256 +name: selenoneine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving selenoneine." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "L-selenoneine metabolic process" NARROW [] +synonym: "selenoneine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006577 ! amino-acid betaine metabolic process +is_a: GO:0052701 ! cellular modified histidine metabolic process +created_by: mah +creation_date: 2014-08-06T09:14:24Z + +[Term] +id: GO:1903257 +name: selenoneine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of selenoneine." [GO_REF:0000068, GOC:TermGenie, PMID:24828577] +synonym: "L-selenoneine biosynthetic process" NARROW [] +synonym: "selenoneine anabolism" EXACT [GOC:TermGenie] +synonym: "selenoneine biosynthesis" EXACT [GOC:TermGenie] +synonym: "selenoneine formation" EXACT [GOC:TermGenie] +synonym: "selenoneine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006578 ! amino-acid betaine biosynthetic process +is_a: GO:0052703 ! cellular modified histidine biosynthetic process +is_a: GO:1903256 ! selenoneine metabolic process +created_by: mah +creation_date: 2014-08-06T09:14:33Z + +[Term] +id: GO:1903258 +name: sorbose import across plasma membrane +namespace: biological_process +def: "The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:2878925] +synonym: "sorbose import into cell" EXACT [] +is_a: GO:0140271 ! hexose import across plasma membrane +created_by: mah +creation_date: 2014-08-06T09:21:53Z + +[Term] +id: GO:1903259 +name: exon-exon junction complex disassembly +namespace: biological_process +def: "The disaggregation of an exon-exon junction complex into its constituent components." [GO_REF:0000079, GOC:sart, GOC:TermGenie, PMID:24967911] +synonym: "EJC disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: sart +creation_date: 2014-08-06T09:44:06Z + +[Term] +id: GO:1903260 +name: protein localization to mating projection tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a mating projection tip." [GO_REF:0000087, GOC:TermGenie, PMID:11952834] +synonym: "protein localisation in mating projection tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to mating projection tip" EXACT [GOC:TermGenie] +synonym: "protein localization in mating projection tip" EXACT [GOC:TermGenie] +synonym: "protein localization to conjugation tube tip" NARROW [] +synonym: "protein localization to shmoo tip" NARROW [] +is_a: GO:1990151 ! protein localization to cell tip +created_by: mah +creation_date: 2014-08-06T13:26:14Z + +[Term] +id: GO:1903264 +name: nitrate reductase activity involved in anaerobic electron transport chain +namespace: molecular_function +def: "Any nitrate reductase activity that is involved in anaerobic electron transport chain." [GO_REF:0000061, GOC:dos, GOC:TermGenie, PMID:12910261] +synonym: "nitrate reductase (acceptor) involved in anaerobic electron transport chain" EXACT [GOC:TermGenie] +synonym: "nitrite:(acceptor) oxidoreductase involved in anaerobic electron transport chain" EXACT [GOC:TermGenie] +synonym: "nitrite:acceptor oxidoreductase involved in anaerobic electron transport chain" EXACT [GOC:TermGenie] +synonym: "respiratory nitrate reductase activity involved in anaerobic electron transport chain" NARROW [GOC:TermGenie] +is_a: GO:0008940 ! nitrate reductase activity +is_a: GO:0009055 ! electron transfer activity +intersection_of: GO:0008940 ! nitrate reductase activity +intersection_of: part_of GO:0019645 ! anaerobic electron transport chain +relationship: part_of GO:0019645 ! anaerobic electron transport chain +created_by: dos +creation_date: 2014-08-07T10:07:07Z + +[Term] +id: GO:1903265 +name: positive regulation of tumor necrosis factor-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23453807] +synonym: "activation of adipocytokine signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of TNF-alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of adipocytokine signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of TNF-alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of tumor necrosis factor alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of adipocytokine signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of TNF-alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of adipocytokine signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of TNF-alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of adipocytokine signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of TNF-alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor alpha-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:0010803 ! regulation of tumor necrosis factor-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway +relationship: positively_regulates GO:0033209 ! tumor necrosis factor-mediated signaling pathway +created_by: bf +creation_date: 2014-08-07T10:26:59Z + +[Term] +id: GO:1903266 +name: regulation of ornithine catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ornithine catabolic process." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:12679340] +comment: An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay). +synonym: "regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ornithine degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0090368 ! regulation of ornithine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006593 ! ornithine catabolic process +relationship: regulates GO:0006593 ! ornithine catabolic process +created_by: bhm +creation_date: 2014-08-08T08:29:33Z + +[Term] +id: GO:1903267 +name: negative regulation of ornithine catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:12679340] +comment: An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay). +synonym: "down regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of ornithine breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of ornithine catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ornithine catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ornithine degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ornithine degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:1903266 ! regulation of ornithine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006593 ! ornithine catabolic process +relationship: negatively_regulates GO:0006593 ! ornithine catabolic process +created_by: bhm +creation_date: 2014-08-08T08:29:42Z + +[Term] +id: GO:1903268 +name: positive regulation of ornithine catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ornithine catabolic process." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:12679340] +synonym: "activation of ornithine breakdown" NARROW [GOC:TermGenie] +synonym: "activation of ornithine catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ornithine catabolism" NARROW [GOC:TermGenie] +synonym: "activation of ornithine degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ornithine degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of ornithine breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of ornithine catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ornithine catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ornithine degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:1903266 ! regulation of ornithine catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006593 ! ornithine catabolic process +relationship: positively_regulates GO:0006593 ! ornithine catabolic process +created_by: bhm +creation_date: 2014-08-08T08:29:50Z + +[Term] +id: GO:1903269 +name: ornithine carbamoyltransferase inhibitor complex +namespace: cellular_component +def: "A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:12679340] +comment: An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay). +synonym: "ornithine carbamoyltransferase arginase complex" NARROW [] +synonym: "OTC-ARGI complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-08-08T08:47:38Z + +[Term] +id: GO:1903270 +name: regulation of cytoplasmic translational elongation through polyproline stretches +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches." [GO_REF:0000058, GOC:TermGenie, PMID:24923804] +is_a: GO:1900247 ! regulation of cytoplasmic translational elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +relationship: regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +created_by: mcc +creation_date: 2014-08-08T14:53:59Z + +[Term] +id: GO:1903271 +name: negative regulation of cytoplasmic translational elongation through polyproline stretches +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches." [GO_REF:0000058, GOC:TermGenie, PMID:24923804] +synonym: "down regulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +synonym: "downregulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +synonym: "inhibition of cytoplasmic translational elongation through polyproline stretches" NARROW [GOC:TermGenie] +is_a: GO:1900248 ! negative regulation of cytoplasmic translational elongation +is_a: GO:1903270 ! regulation of cytoplasmic translational elongation through polyproline stretches +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +relationship: negatively_regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +created_by: mcc +creation_date: 2014-08-08T14:54:08Z + +[Term] +id: GO:1903272 +name: positive regulation of cytoplasmic translational elongation through polyproline stretches +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches." [GO_REF:0000058, GOC:TermGenie, PMID:24923804] +synonym: "activation of cytoplasmic translational elongation through polyproline stretches" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +synonym: "upregulation of cytoplasmic translational elongation through polyproline stretches" EXACT [GOC:TermGenie] +is_a: GO:1900249 ! positive regulation of cytoplasmic translational elongation +is_a: GO:1903270 ! regulation of cytoplasmic translational elongation through polyproline stretches +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +relationship: positively_regulates GO:0097622 ! cytoplasmic translational elongation through polyproline stretches +created_by: mcc +creation_date: 2014-08-08T14:54:16Z + +[Term] +id: GO:1903276 +name: regulation of sodium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1903273 +def: "Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] +synonym: "regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "regulation of sodium ion export" RELATED [] +synonym: "regulation of sodium ion export from cell" EXACT [] +is_a: GO:1902305 ! regulation of sodium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036376 ! sodium ion export across plasma membrane +relationship: regulates GO:0036376 ! sodium ion export across plasma membrane +created_by: rl +creation_date: 2014-08-08T17:06:46Z + +[Term] +id: GO:1903277 +name: negative regulation of sodium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1903274 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] +synonym: "down regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "down regulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "down regulation of sodium ion export from cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "down-regulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "down-regulation of sodium ion export from cell" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium export" RELATED [GOC:TermGenie] +synonym: "downregulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "downregulation of sodium ion export from cell" EXACT [GOC:TermGenie] +synonym: "inhibition of sodium export" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium ion export" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium ion export from cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "negative regulation of sodium ion export" RELATED [] +synonym: "negative regulation of sodium ion export from cell" EXACT [] +is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport +is_a: GO:1903276 ! regulation of sodium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036376 ! sodium ion export across plasma membrane +relationship: negatively_regulates GO:0036376 ! sodium ion export across plasma membrane +created_by: rl +creation_date: 2014-08-08T17:10:22Z + +[Term] +id: GO:1903278 +name: positive regulation of sodium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1903275 +def: "Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17095720] +synonym: "activation of sodium export" NARROW [GOC:TermGenie] +synonym: "activation of sodium ion export" NARROW [GOC:TermGenie] +synonym: "activation of sodium ion export from cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "positive regulation of sodium ion export" RELATED [] +synonym: "positive regulation of sodium ion export from cell" EXACT [] +synonym: "up regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "up regulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "up regulation of sodium ion export from cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium export" RELATED [GOC:TermGenie] +synonym: "up-regulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "up-regulation of sodium ion export from cell" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium export" RELATED [GOC:TermGenie] +synonym: "upregulation of sodium ion export" RELATED [GOC:TermGenie] +synonym: "upregulation of sodium ion export from cell" EXACT [GOC:TermGenie] +is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport +is_a: GO:1903276 ! regulation of sodium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036376 ! sodium ion export across plasma membrane +relationship: positively_regulates GO:0036376 ! sodium ion export across plasma membrane +created_by: rl +creation_date: 2014-08-08T17:10:30Z + +[Term] +id: GO:1903279 +name: regulation of calcium:sodium antiporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19683723] +synonym: "regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005432 ! calcium:sodium antiporter activity +relationship: regulates GO:0005432 ! calcium:sodium antiporter activity +created_by: rl +creation_date: 2014-08-11T12:53:30Z + +[Term] +id: GO:1903280 +name: negative regulation of calcium:sodium antiporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19683723] +synonym: "down regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "down regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "down regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "down regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "down-regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "down-regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "downregulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "downregulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "inhibition of calcium:sodium antiporter activity" NARROW [GOC:TermGenie] +synonym: "inhibition of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "inhibition of sodium/calcium exchanger" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "negative regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "negative regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity +is_a: GO:1903279 ! regulation of calcium:sodium antiporter activity +is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005432 ! calcium:sodium antiporter activity +relationship: negatively_regulates GO:0005432 ! calcium:sodium antiporter activity +created_by: rl +creation_date: 2014-08-11T12:53:38Z + +[Term] +id: GO:1903281 +name: positive regulation of calcium:sodium antiporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19683723] +synonym: "activation of calcium:sodium antiporter activity" NARROW [GOC:TermGenie] +synonym: "activation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "activation of sodium/calcium exchanger" NARROW [GOC:TermGenie] +synonym: "activation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "positive regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "positive regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "up regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "up regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "up-regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "up-regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +synonym: "upregulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] +synonym: "upregulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium:calcium exchange" RELATED [GOC:TermGenie] +is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity +is_a: GO:1903279 ! regulation of calcium:sodium antiporter activity +is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005432 ! calcium:sodium antiporter activity +relationship: positively_regulates GO:0005432 ! calcium:sodium antiporter activity +created_by: rl +creation_date: 2014-08-11T12:53:47Z + +[Term] +id: GO:1903282 +name: regulation of glutathione peroxidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutathione peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +is_a: GO:2000468 ! regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004602 ! glutathione peroxidase activity +relationship: regulates GO:0004602 ! glutathione peroxidase activity +created_by: bf +creation_date: 2014-08-11T13:14:13Z + +[Term] +id: GO:1903283 +name: negative regulation of glutathione peroxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glutathione:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GSH peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of reduced glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of selenium-glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +is_a: GO:1903282 ! regulation of glutathione peroxidase activity +is_a: GO:2000469 ! negative regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004602 ! glutathione peroxidase activity +relationship: negatively_regulates GO:0004602 ! glutathione peroxidase activity +created_by: bf +creation_date: 2014-08-11T13:14:22Z + +[Term] +id: GO:1903284 +name: positive regulation of glutathione peroxidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23507046] +synonym: "activation of glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glutathione:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of GSH peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of reduced glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of selenium-glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "enhancement of GPX activity" EXACT [PMID:23507046] +synonym: "positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of GSH peroxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] +is_a: GO:1903282 ! regulation of glutathione peroxidase activity +is_a: GO:2000470 ! positive regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004602 ! glutathione peroxidase activity +relationship: positively_regulates GO:0004602 ! glutathione peroxidase activity +created_by: bf +creation_date: 2014-08-11T13:14:30Z + +[Term] +id: GO:1903285 +name: positive regulation of hydrogen peroxide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23507046] +synonym: "activation of detoxification of H2O2" RELATED [GOC:TermGenie] +synonym: "activation of detoxification of hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "activation of H2O2 catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of H2O2 scavenging" RELATED [GOC:TermGenie] +synonym: "activation of hydrogen peroxide breakdown" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen peroxide catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen peroxide catabolism" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen peroxide degradation" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen peroxide removal" RELATED [GOC:TermGenie] +synonym: "activation of hydrogen peroxide scavenging" RELATED [GOC:TermGenie] +synonym: "positive regulation of detoxification of H2O2" RELATED [GOC:TermGenie] +synonym: "positive regulation of detoxification of hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "positive regulation of H2O2 catabolic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of H2O2 scavenging" RELATED [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide removal" RELATED [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide scavenging" RELATED [GOC:TermGenie] +synonym: "up regulation of detoxification of H2O2" RELATED [GOC:TermGenie] +synonym: "up regulation of detoxification of hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "up regulation of H2O2 catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of H2O2 scavenging" RELATED [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide removal" RELATED [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide scavenging" RELATED [GOC:TermGenie] +synonym: "up-regulation of detoxification of H2O2" RELATED [GOC:TermGenie] +synonym: "up-regulation of detoxification of hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "up-regulation of H2O2 catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of H2O2 scavenging" RELATED [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide removal" RELATED [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide scavenging" RELATED [GOC:TermGenie] +synonym: "upregulation of detoxification of H2O2" RELATED [GOC:TermGenie] +synonym: "upregulation of detoxification of hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "upregulation of H2O2 catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of H2O2 scavenging" RELATED [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide removal" RELATED [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide scavenging" RELATED [GOC:TermGenie] +is_a: GO:0010726 ! positive regulation of hydrogen peroxide metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2000295 ! regulation of hydrogen peroxide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042744 ! hydrogen peroxide catabolic process +relationship: positively_regulates GO:0042744 ! hydrogen peroxide catabolic process +created_by: bf +creation_date: 2014-08-11T13:28:40Z + +[Term] +id: GO:1903286 +name: regulation of potassium ion import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of potassium ion import." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:10636900] +synonym: "regulation of potassium import" EXACT [GOC:TermGenie] +synonym: "regulation of potassium ion uptake" EXACT [GOC:TermGenie] +is_a: GO:1901379 ! regulation of potassium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990573 ! potassium ion import across plasma membrane +relationship: regulates GO:1990573 ! potassium ion import across plasma membrane +created_by: rl +creation_date: 2014-08-11T14:26:16Z + +[Term] +id: GO:1903287 +name: negative regulation of potassium ion import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:10636900] +synonym: "down regulation of potassium import" BROAD [GOC:TermGenie] +synonym: "down regulation of potassium ion import" BROAD [GOC:TermGenie] +synonym: "down regulation of potassium ion uptake" BROAD [GOC:TermGenie] +synonym: "down-regulation of potassium import" BROAD [GOC:TermGenie] +synonym: "down-regulation of potassium ion import" BROAD [GOC:TermGenie] +synonym: "down-regulation of potassium ion uptake" BROAD [GOC:TermGenie] +synonym: "downregulation of potassium import" BROAD [GOC:TermGenie] +synonym: "downregulation of potassium ion import" BROAD [GOC:TermGenie] +synonym: "downregulation of potassium ion uptake" BROAD [GOC:TermGenie] +synonym: "inhibition of potassium import" NARROW [GOC:TermGenie] +synonym: "inhibition of potassium ion import" NARROW [GOC:TermGenie] +synonym: "inhibition of potassium ion uptake" NARROW [GOC:TermGenie] +synonym: "negative regulation of potassium import" BROAD [GOC:TermGenie] +synonym: "negative regulation of potassium ion import" BROAD [] +synonym: "negative regulation of potassium ion uptake" BROAD [GOC:TermGenie] +is_a: GO:1901380 ! negative regulation of potassium ion transmembrane transport +is_a: GO:1903286 ! regulation of potassium ion import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990573 ! potassium ion import across plasma membrane +relationship: negatively_regulates GO:1990573 ! potassium ion import across plasma membrane +created_by: rl +creation_date: 2014-08-11T14:26:24Z + +[Term] +id: GO:1903288 +name: positive regulation of potassium ion import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:10636900] +synonym: "activation of potassium import" NARROW [GOC:TermGenie] +synonym: "activation of potassium ion import" NARROW [GOC:TermGenie] +synonym: "activation of potassium ion uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of potassium import" EXACT [GOC:TermGenie] +synonym: "positive regulation of potassium ion import" BROAD [] +synonym: "positive regulation of potassium ion uptake" EXACT [GOC:TermGenie] +synonym: "up regulation of potassium import" EXACT [GOC:TermGenie] +synonym: "up regulation of potassium ion import" EXACT [GOC:TermGenie] +synonym: "up regulation of potassium ion uptake" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium import" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium ion import" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium ion uptake" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium import" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium ion import" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium ion uptake" EXACT [GOC:TermGenie] +is_a: GO:1901381 ! positive regulation of potassium ion transmembrane transport +is_a: GO:1903286 ! regulation of potassium ion import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990573 ! potassium ion import across plasma membrane +relationship: positively_regulates GO:1990573 ! potassium ion import across plasma membrane +created_by: rl +creation_date: 2014-08-11T14:26:32Z + +[Term] +id: GO:1903289 +name: obsolete regulation of ATP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:10636900] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:0043462 +created_by: rl +creation_date: 2014-08-11T14:36:39Z + +[Term] +id: GO:1903290 +name: obsolete negative regulation of ATP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:10636900] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "down regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "downregulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:0032780 +created_by: rl +creation_date: 2014-08-11T14:36:47Z + +[Term] +id: GO:1903291 +name: obsolete positive regulation of ATP catabolic process +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP catabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:10636900] +comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism. +synonym: "activation of ATP breakdown" NARROW [GOC:TermGenie] +synonym: "activation of ATP catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ATP catabolism" NARROW [GOC:TermGenie] +synonym: "activation of ATP degradation" NARROW [GOC:TermGenie] +synonym: "activation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "up regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP hydrolysis" NARROW [GOC:TermGenie] +synonym: "upregulation of ATP breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP hydrolysis" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:0032781 +created_by: rl +creation_date: 2014-08-11T14:36:55Z + +[Term] +id: GO:1903292 +name: protein localization to Golgi membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902] +synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie] +is_a: GO:0034067 ! protein localization to Golgi apparatus +is_a: GO:0072657 ! protein localization to membrane +created_by: mah +creation_date: 2014-08-12T14:22:31Z + +[Term] +id: GO:1903293 +name: phosphatase complex +namespace: cellular_component +def: "A protein complex which is capable of phosphatase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:24766807] +comment: An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay). +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2014-08-13T10:25:32Z + +[Term] +id: GO:1903294 +name: regulation of glutamate secretion, neurotransmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype +is_a: GO:0014048 ! regulation of glutamate secretion +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0051966 ! regulation of synaptic transmission, glutamatergic +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061535 ! glutamate secretion, neurotransmission +relationship: regulates GO:0061535 ! glutamate secretion, neurotransmission +created_by: pad +creation_date: 2014-08-13T13:54:15Z + +[Term] +id: GO:1903295 +name: negative regulation of glutamate secretion, neurotransmission +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype +synonym: "down regulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "inhibition of glutamate secretion, neurotransmission" NARROW [GOC:TermGenie] +is_a: GO:0014050 ! negative regulation of glutamate secretion +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:0051967 ! negative regulation of synaptic transmission, glutamatergic +is_a: GO:1903294 ! regulation of glutamate secretion, neurotransmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061535 ! glutamate secretion, neurotransmission +relationship: negatively_regulates GO:0061535 ! glutamate secretion, neurotransmission +created_by: pad +creation_date: 2014-08-13T13:54:23Z + +[Term] +id: GO:1903296 +name: positive regulation of glutamate secretion, neurotransmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter." [GO_REF:0000058, GOC:TermGenie, PMID:16782817] +comment: An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype +synonym: "activation of glutamate secretion, neurotransmission" NARROW [GOC:TermGenie] +synonym: "up regulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamate secretion, neurotransmission" EXACT [GOC:TermGenie] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:0014049 ! positive regulation of glutamate secretion +is_a: GO:0051968 ! positive regulation of synaptic transmission, glutamatergic +is_a: GO:1903294 ! regulation of glutamate secretion, neurotransmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061535 ! glutamate secretion, neurotransmission +relationship: positively_regulates GO:0061535 ! glutamate secretion, neurotransmission +created_by: pad +creation_date: 2014-08-13T13:54:31Z + +[Term] +id: GO:1903297 +name: regulation of hypoxia-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of hypoxia-induced apoptosis" RELATED [GOC:bf] +synonym: "regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "regulation of intrinsic apoptotic signaling pathway in response to hypoxia" EXACT [GOC:bf] +is_a: GO:1900037 ! regulation of cellular response to hypoxia +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990144 ! intrinsic apoptotic signaling pathway in response to hypoxia +relationship: regulates GO:1990144 ! intrinsic apoptotic signaling pathway in response to hypoxia +created_by: bf +creation_date: 2014-08-14T14:47:48Z + +[Term] +id: GO:1903298 +name: negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24553947] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to hypoxia" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to hypoxia" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to hypoxia" EXACT [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to hypoxia" NARROW [GOC:TermGenie] +synonym: "negative regulation of hypoxia-induced apoptosis" RELATED [GOC:bf] +synonym: "negative regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +synonym: "negative regulation of intrinsic apoptotic signaling pathway in response to hypoxia" EXACT [GOC:bf] +synonym: "protection against hypoxia-induced apoptosis" RELATED [GOC:bf] +is_a: GO:1900038 ! negative regulation of cellular response to hypoxia +is_a: GO:1903297 ! regulation of hypoxia-induced intrinsic apoptotic signaling pathway +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990144 ! intrinsic apoptotic signaling pathway in response to hypoxia +relationship: negatively_regulates GO:1990144 ! intrinsic apoptotic signaling pathway in response to hypoxia +created_by: bf +creation_date: 2014-08-14T14:47:56Z + +[Term] +id: GO:1903299 +name: regulation of hexokinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hexokinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004396 ! hexokinase activity +relationship: regulates GO:0004396 ! hexokinase activity +created_by: mr +creation_date: 2014-08-15T23:17:53Z + +[Term] +id: GO:1903300 +name: negative regulation of hexokinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "down regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "down regulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "down regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "down regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "down regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "down-regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "downregulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "downregulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "downregulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "downregulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ATP-dependent hexokinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:D-hexose 6-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucose ATP phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase (phosphorylating)" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase D" RELATED [GOC:TermGenie] +synonym: "inhibition of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "inhibition of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hexokinase type IV glucokinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "negative regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0033673 ! negative regulation of kinase activity +is_a: GO:1903299 ! regulation of hexokinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004396 ! hexokinase activity +relationship: negatively_regulates GO:0004396 ! hexokinase activity +created_by: mr +creation_date: 2014-08-15T23:18:01Z + +[Term] +id: GO:1903301 +name: positive regulation of hexokinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hexokinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "activation of ATP-dependent hexokinase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP:D-hexose 6-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucose ATP phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase (phosphorylating)" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "activation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "activation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "activation of hexokinase type IV glucokinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "positive regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "up regulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "up regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "up regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "up regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "up-regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "upregulation of hexokinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hexokinase D" RELATED [GOC:TermGenie] +synonym: "upregulation of hexokinase type I activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hexokinase type II activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hexokinase type III activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hexokinase type IV" RELATED [GOC:TermGenie] +synonym: "upregulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] +synonym: "upregulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0033674 ! positive regulation of kinase activity +is_a: GO:1903299 ! regulation of hexokinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004396 ! hexokinase activity +relationship: positively_regulates GO:0004396 ! hexokinase activity +created_by: mr +creation_date: 2014-08-15T23:18:09Z + +[Term] +id: GO:1903302 +name: regulation of pyruvate kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pyruvate kinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0006110 ! regulation of glycolytic process +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004743 ! pyruvate kinase activity +relationship: regulates GO:0004743 ! pyruvate kinase activity +created_by: mr +creation_date: 2014-08-15T23:25:51Z + +[Term] +id: GO:1903303 +name: negative regulation of pyruvate kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "down regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ATP:pyruvate 2-O-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphoenol transphosphorylase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphoenolpyruvate kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of pyruvate kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0045820 ! negative regulation of glycolytic process +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1903302 ! regulation of pyruvate kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004743 ! pyruvate kinase activity +relationship: negatively_regulates GO:0004743 ! pyruvate kinase activity +created_by: mr +creation_date: 2014-08-15T23:25:58Z + +[Term] +id: GO:1903304 +name: positive regulation of pyruvate kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] +synonym: "activation of ATP:pyruvate 2-O-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphoenol transphosphorylase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphoenolpyruvate kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of pyruvate kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pyruvate kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0045821 ! positive regulation of glycolytic process +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1903302 ! regulation of pyruvate kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004743 ! pyruvate kinase activity +relationship: positively_regulates GO:0004743 ! pyruvate kinase activity +created_by: mr +creation_date: 2014-08-15T23:26:06Z + +[Term] +id: GO:1903305 +name: regulation of regulated secretory pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of regulated secretory pathway." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:12526776] +comment: An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. +is_a: GO:0017157 ! regulation of exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045055 ! regulated exocytosis +relationship: regulates GO:0045055 ! regulated exocytosis +created_by: pad +creation_date: 2014-08-18T10:04:53Z + +[Term] +id: GO:1903306 +name: negative regulation of regulated secretory pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:12526776] +comment: An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. +synonym: "down regulation of regulated secretory pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulated secretory pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of regulated secretory pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of regulated secretory pathway" NARROW [GOC:TermGenie] +is_a: GO:0045920 ! negative regulation of exocytosis +is_a: GO:1903305 ! regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045055 ! regulated exocytosis +relationship: negatively_regulates GO:0045055 ! regulated exocytosis +created_by: pad +creation_date: 2014-08-18T10:05:02Z + +[Term] +id: GO:1903307 +name: positive regulation of regulated secretory pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of regulated secretory pathway." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:12526776] +comment: An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. +synonym: "activation of regulated secretory pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of regulated secretory pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulated secretory pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of regulated secretory pathway" EXACT [GOC:TermGenie] +is_a: GO:0045921 ! positive regulation of exocytosis +is_a: GO:1903305 ! regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045055 ! regulated exocytosis +relationship: positively_regulates GO:0045055 ! regulated exocytosis +created_by: pad +creation_date: 2014-08-18T10:05:10Z + +[Term] +id: GO:1903311 +name: regulation of mRNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of mRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016071 ! mRNA metabolic process +relationship: regulates GO:0016071 ! mRNA metabolic process +created_by: vw +creation_date: 2014-08-18T11:52:26Z + +[Term] +id: GO:1903312 +name: negative regulation of mRNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of mRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of mRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016071 ! mRNA metabolic process +relationship: negatively_regulates GO:0016071 ! mRNA metabolic process +created_by: vw +creation_date: 2014-08-18T11:52:34Z + +[Term] +id: GO:1903313 +name: positive regulation of mRNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of mRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of mRNA metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1903311 ! regulation of mRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016071 ! mRNA metabolic process +relationship: positively_regulates GO:0016071 ! mRNA metabolic process +created_by: vw +creation_date: 2014-08-18T11:52:42Z + +[Term] +id: GO:1903314 +name: regulation of nitrogen cycle metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071941 ! nitrogen cycle metabolic process +relationship: regulates GO:0071941 ! nitrogen cycle metabolic process +created_by: vw +creation_date: 2014-08-18T12:57:34Z + +[Term] +id: GO:1903315 +name: negative regulation of nitrogen cycle metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of nitrogen cycle metabolic process" NARROW [GOC:TermGenie] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1903314 ! regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071941 ! nitrogen cycle metabolic process +relationship: negatively_regulates GO:0071941 ! nitrogen cycle metabolic process +created_by: vw +creation_date: 2014-08-18T12:57:42Z + +[Term] +id: GO:1903316 +name: positive regulation of nitrogen cycle metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of nitrogen cycle metabolic process" NARROW [GOC:TermGenie] +synonym: "up regulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of nitrogen cycle metabolic process" EXACT [GOC:TermGenie] +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1903314 ! regulation of nitrogen cycle metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071941 ! nitrogen cycle metabolic process +relationship: positively_regulates GO:0071941 ! nitrogen cycle metabolic process +created_by: vw +creation_date: 2014-08-18T12:57:50Z + +[Term] +id: GO:1903317 +name: regulation of protein maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein maturation." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051604 ! protein maturation +relationship: regulates GO:0051604 ! protein maturation +created_by: vw +creation_date: 2014-08-18T12:59:07Z + +[Term] +id: GO:1903318 +name: negative regulation of protein maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of protein maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein maturation" NARROW [GOC:TermGenie] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:1903317 ! regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051604 ! protein maturation +relationship: negatively_regulates GO:0051604 ! protein maturation +created_by: vw +creation_date: 2014-08-18T12:59:15Z + +[Term] +id: GO:1903319 +name: positive regulation of protein maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein maturation." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of protein maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of protein maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein maturation" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:1903317 ! regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051604 ! protein maturation +relationship: positively_regulates GO:0051604 ! protein maturation +created_by: vw +creation_date: 2014-08-18T12:59:23Z + +[Term] +id: GO:1903320 +name: regulation of protein modification by small protein conjugation or removal +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070647 ! protein modification by small protein conjugation or removal +relationship: regulates GO:0070647 ! protein modification by small protein conjugation or removal +created_by: vw +creation_date: 2014-08-18T13:01:00Z + +[Term] +id: GO:1903321 +name: negative regulation of protein modification by small protein conjugation or removal +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +synonym: "downregulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +synonym: "inhibition of protein modification by small protein conjugation or removal" NARROW [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070647 ! protein modification by small protein conjugation or removal +relationship: negatively_regulates GO:0070647 ! protein modification by small protein conjugation or removal +created_by: vw +creation_date: 2014-08-18T13:01:08Z + +[Term] +id: GO:1903322 +name: positive regulation of protein modification by small protein conjugation or removal +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of protein modification by small protein conjugation or removal" NARROW [GOC:TermGenie] +synonym: "up regulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +synonym: "upregulation of protein modification by small protein conjugation or removal" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070647 ! protein modification by small protein conjugation or removal +relationship: positively_regulates GO:0070647 ! protein modification by small protein conjugation or removal +created_by: vw +creation_date: 2014-08-18T13:01:15Z + +[Term] +id: GO:1903323 +name: regulation of snoRNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of snoRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016074 ! snoRNA metabolic process +relationship: regulates GO:0016074 ! snoRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:05:17Z + +[Term] +id: GO:1903324 +name: negative regulation of snoRNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of snoRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of snoRNA metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:1903323 ! regulation of snoRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016074 ! snoRNA metabolic process +relationship: negatively_regulates GO:0016074 ! snoRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:05:25Z + +[Term] +id: GO:1903325 +name: positive regulation of snoRNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of snoRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of snoRNA metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of snoRNA metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of snoRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of snoRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1903323 ! regulation of snoRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016074 ! snoRNA metabolic process +relationship: positively_regulates GO:0016074 ! snoRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:05:33Z + +[Term] +id: GO:1903326 +name: regulation of tRNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of tRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006399 ! tRNA metabolic process +relationship: regulates GO:0006399 ! tRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:08:50Z + +[Term] +id: GO:1903327 +name: negative regulation of tRNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of tRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of tRNA metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of tRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:1903326 ! regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006399 ! tRNA metabolic process +relationship: negatively_regulates GO:0006399 ! tRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:08:58Z + +[Term] +id: GO:1903328 +name: positive regulation of tRNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA metabolic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of tRNA metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of tRNA metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of tRNA metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of tRNA metabolism" EXACT [GOC:TermGenie] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1903326 ! regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006399 ! tRNA metabolic process +relationship: positively_regulates GO:0006399 ! tRNA metabolic process +created_by: vw +creation_date: 2014-08-18T13:09:06Z + +[Term] +id: GO:1903329 +name: regulation of iron-sulfur cluster assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016226 ! iron-sulfur cluster assembly +relationship: regulates GO:0016226 ! iron-sulfur cluster assembly +created_by: vw +creation_date: 2014-08-18T13:12:41Z + +[Term] +id: GO:1903330 +name: negative regulation of iron-sulfur cluster assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of iron-sulfur cluster assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of iron-sulphur cluster assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1903329 ! regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016226 ! iron-sulfur cluster assembly +relationship: negatively_regulates GO:0016226 ! iron-sulfur cluster assembly +created_by: vw +creation_date: 2014-08-18T13:12:50Z + +[Term] +id: GO:1903331 +name: positive regulation of iron-sulfur cluster assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of iron-sulfur cluster assembly" NARROW [GOC:TermGenie] +synonym: "activation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of iron-sulphur cluster assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of iron-sulfur cluster assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of iron-sulfur cluster biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of iron-sulphur cluster assembly" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1903329 ! regulation of iron-sulfur cluster assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016226 ! iron-sulfur cluster assembly +relationship: positively_regulates GO:0016226 ! iron-sulfur cluster assembly +created_by: vw +creation_date: 2014-08-18T13:12:57Z + +[Term] +id: GO:1903332 +name: regulation of protein folding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein folding." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006457 ! protein folding +relationship: regulates GO:0006457 ! protein folding +created_by: vw +creation_date: 2014-08-18T13:14:34Z + +[Term] +id: GO:1903333 +name: negative regulation of protein folding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein folding." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "down regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "down regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "down regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "down regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "down regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "down regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "down regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of protein folding" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "down-regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "down-regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "down-regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein folding" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "downregulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "downregulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "downregulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "downregulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "downregulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "downregulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "downregulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of protein folding" EXACT [GOC:TermGenie] +synonym: "inhibition of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "inhibition of chaperone activity" RELATED [GOC:TermGenie] +synonym: "inhibition of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "inhibition of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "inhibition of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "inhibition of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "inhibition of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of protein folding" NARROW [GOC:TermGenie] +synonym: "negative regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "negative regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "negative regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1903332 ! regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006457 ! protein folding +relationship: negatively_regulates GO:0006457 ! protein folding +created_by: vw +creation_date: 2014-08-18T13:14:42Z + +[Term] +id: GO:1903334 +name: positive regulation of protein folding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein folding." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "activation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "activation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "activation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "activation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "activation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "activation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "activation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "activation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "activation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "activation of protein folding" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "positive regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "positive regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "up regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "up regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "up regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "up regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "up regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "up regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "up regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of protein folding" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "up-regulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "up-regulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "up-regulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein folding" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-tubulin folding" NARROW [GOC:TermGenie] +synonym: "upregulation of beta-tubulin folding" NARROW [GOC:TermGenie] +synonym: "upregulation of chaperone activity" RELATED [GOC:TermGenie] +synonym: "upregulation of chaperonin ATPase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of chaperonin-mediated tubulin folding" NARROW [GOC:TermGenie] +synonym: "upregulation of co-chaperone activity" RELATED [GOC:TermGenie] +synonym: "upregulation of co-chaperonin activity" RELATED [GOC:TermGenie] +synonym: "upregulation of glycoprotein-specific chaperone activity" RELATED [GOC:TermGenie] +synonym: "upregulation of non-chaperonin molecular chaperone ATPase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of protein complex assembly, multichaperone pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of protein folding" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1903332 ! regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006457 ! protein folding +relationship: positively_regulates GO:0006457 ! protein folding +created_by: vw +creation_date: 2014-08-18T13:14:50Z + +[Term] +id: GO:1903335 +name: regulation of vacuolar transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007034 ! vacuolar transport +relationship: regulates GO:0007034 ! vacuolar transport +created_by: vw +creation_date: 2014-08-18T13:16:04Z + +[Term] +id: GO:1903336 +name: negative regulation of vacuolar transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie] +synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie] +synonym: "inhibition of vacuolar transport" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1903335 ! regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007034 ! vacuolar transport +relationship: negatively_regulates GO:0007034 ! vacuolar transport +created_by: vw +creation_date: 2014-08-18T13:16:11Z + +[Term] +id: GO:1903337 +name: positive regulation of vacuolar transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of vacuolar transport" NARROW [GOC:TermGenie] +synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie] +synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1903335 ! regulation of vacuolar transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007034 ! vacuolar transport +relationship: positively_regulates GO:0007034 ! vacuolar transport +created_by: vw +creation_date: 2014-08-18T13:16:19Z + +[Term] +id: GO:1903338 +name: regulation of cell wall organization or biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071554 ! cell wall organization or biogenesis +relationship: regulates GO:0071554 ! cell wall organization or biogenesis +created_by: vw +creation_date: 2014-08-18T13:20:50Z + +[Term] +id: GO:1903339 +name: negative regulation of cell wall organization or biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cell wall organisation or biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of cell wall organization or biogenesis at cellular level" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular cell wall organisation or biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071554 ! cell wall organization or biogenesis +relationship: negatively_regulates GO:0071554 ! cell wall organization or biogenesis +created_by: vw +creation_date: 2014-08-18T13:20:58Z + +[Term] +id: GO:1903340 +name: positive regulation of cell wall organization or biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of cell wall organisation or biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of cell wall organization or biogenesis at cellular level" NARROW [GOC:TermGenie] +synonym: "activation of cellular cell wall organisation or biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of cellular cell wall organization or biogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cell wall organization or biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cell wall organization or biogenesis at cellular level" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular cell wall organisation or biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular cell wall organization or biogenesis" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071554 ! cell wall organization or biogenesis +relationship: positively_regulates GO:0071554 ! cell wall organization or biogenesis +created_by: vw +creation_date: 2014-08-18T13:21:06Z + +[Term] +id: GO:1903341 +name: regulation of meiotic DNA double-strand break formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation." [GO_REF:0000058, GOC:TermGenie, PMID:25103240] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042138 ! meiotic DNA double-strand break formation +relationship: regulates GO:0042138 ! meiotic DNA double-strand break formation +created_by: mcc +creation_date: 2014-08-18T21:31:54Z + +[Term] +id: GO:1903342 +name: negative regulation of meiotic DNA double-strand break formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation." [GO_REF:0000058, GOC:TermGenie, PMID:25103240] +synonym: "down regulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +synonym: "inhibition of meiotic DNA double-strand break formation" NARROW [GOC:TermGenie] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:1903341 ! regulation of meiotic DNA double-strand break formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042138 ! meiotic DNA double-strand break formation +relationship: negatively_regulates GO:0042138 ! meiotic DNA double-strand break formation +created_by: mcc +creation_date: 2014-08-18T21:32:03Z + +[Term] +id: GO:1903343 +name: positive regulation of meiotic DNA double-strand break formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation." [GO_REF:0000058, GOC:TermGenie, PMID:25103240] +synonym: "activation of meiotic DNA double-strand break formation" NARROW [GOC:TermGenie] +synonym: "up regulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic DNA double-strand break formation" EXACT [GOC:TermGenie] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1903341 ! regulation of meiotic DNA double-strand break formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042138 ! meiotic DNA double-strand break formation +relationship: positively_regulates GO:0042138 ! meiotic DNA double-strand break formation +created_by: mcc +creation_date: 2014-08-18T21:32:11Z + +[Term] +id: GO:1903344 +name: regulation of protein polyglycylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein polyglycylation." [GO_REF:0000058, GOC:sart, GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018094 ! protein polyglycylation +relationship: regulates GO:0018094 ! protein polyglycylation +created_by: sart +creation_date: 2014-08-19T09:32:08Z + +[Term] +id: GO:1903345 +name: negative regulation of protein polyglycylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation." [GO_REF:0000058, GOC:sart, GOC:TermGenie] +synonym: "down regulation of protein polyglycylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein polyglycylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein polyglycylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein polyglycylation" NARROW [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1903344 ! regulation of protein polyglycylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018094 ! protein polyglycylation +relationship: negatively_regulates GO:0018094 ! protein polyglycylation +created_by: sart +creation_date: 2014-08-19T09:32:16Z + +[Term] +id: GO:1903346 +name: positive regulation of protein polyglycylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein polyglycylation." [GO_REF:0000058, GOC:sart, GOC:TermGenie, PMID:21298005] +synonym: "activation of protein polyglycylation" NARROW [GOC:TermGenie] +synonym: "up regulation of protein polyglycylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein polyglycylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein polyglycylation" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1903344 ! regulation of protein polyglycylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018094 ! protein polyglycylation +relationship: positively_regulates GO:0018094 ! protein polyglycylation +created_by: sart +creation_date: 2014-08-19T09:32:24Z + +[Term] +id: GO:1903347 +name: negative regulation of bicellular tight junction assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25050009] +synonym: "down regulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "downregulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "inhibition of tight junction assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of tight junction formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of tight junction formation" EXACT [GOC:TermGenie] +is_a: GO:1901889 ! negative regulation of cell junction assembly +is_a: GO:2000810 ! regulation of bicellular tight junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070830 ! bicellular tight junction assembly +relationship: negatively_regulates GO:0070830 ! bicellular tight junction assembly +created_by: pr +creation_date: 2014-08-19T11:02:14Z + +[Term] +id: GO:1903348 +name: positive regulation of bicellular tight junction assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tight junction assembly." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25050009] +synonym: "activation of tight junction assembly" NARROW [GOC:TermGenie] +synonym: "activation of tight junction formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "up regulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of tight junction formation" EXACT [GOC:TermGenie] +synonym: "upregulation of tight junction assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of tight junction formation" EXACT [GOC:TermGenie] +is_a: GO:1901890 ! positive regulation of cell junction assembly +is_a: GO:2000810 ! regulation of bicellular tight junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070830 ! bicellular tight junction assembly +relationship: positively_regulates GO:0070830 ! bicellular tight junction assembly +created_by: pr +creation_date: 2014-08-19T11:05:06Z + +[Term] +id: GO:1903349 +name: omegasome membrane +namespace: cellular_component +def: "Any membrane that is part of an omegasome." [GO_REF:0000064, GOC:mf, GOC:TermGenie, PMID:18725538, PMID:24591649] +is_a: GO:0098588 ! bounding membrane of organelle +created_by: pr +creation_date: 2014-08-19T12:33:09Z + +[Term] +id: GO:1903350 +name: response to dopamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:11118945] +is_a: GO:0042493 ! response to drug +is_a: GO:0071869 ! response to catecholamine +created_by: mr +creation_date: 2014-08-19T19:33:26Z + +[Term] +id: GO:1903351 +name: cellular response to dopamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:11118945] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071870 ! cellular response to catecholamine stimulus +is_a: GO:1903350 ! response to dopamine +created_by: mr +creation_date: 2014-08-19T19:33:35Z + +[Term] +id: GO:1903352 +name: L-ornithine transmembrane transport +namespace: biological_process +def: "The directed movement of L-ornithine across a membrane." [GO_REF:0000069, GOC:krc, GOC:TermGenie, PMID:8195186] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015822 ! ornithine transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: pr +creation_date: 2014-08-20T13:01:38Z + +[Term] +id: GO:1903353 +name: regulation of nucleus organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282] +synonym: "regulation of nuclear morphology" RELATED [GOC:TermGenie] +synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of nucleus organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006997 ! nucleus organization +relationship: regulates GO:0006997 ! nucleus organization +created_by: hjd +creation_date: 2014-08-20T19:36:16Z + +[Term] +id: GO:1903354 +name: regulation of distal tip cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of distal tip cell migration." [GO_REF:0000058, GOC:mm2, GOC:TermGenie, PMID:24968003] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097628 ! distal tip cell migration +relationship: regulates GO:0097628 ! distal tip cell migration +created_by: pr +creation_date: 2014-08-21T10:05:08Z + +[Term] +id: GO:1903355 +name: negative regulation of distal tip cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration." [GO_REF:0000058, GOC:mm2, GOC:TermGenie, PMID:24968003] +synonym: "down regulation of distal tip cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of distal tip cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of distal tip cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of distal tip cell migration" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:1903354 ! regulation of distal tip cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097628 ! distal tip cell migration +relationship: negatively_regulates GO:0097628 ! distal tip cell migration +created_by: pr +creation_date: 2014-08-21T10:05:17Z + +[Term] +id: GO:1903356 +name: positive regulation of distal tip cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of distal tip cell migration." [GO_REF:0000058, GOC:mm2, GOC:TermGenie, PMID:24968003] +synonym: "activation of distal tip cell migration" NARROW [GOC:TermGenie] +synonym: "up regulation of distal tip cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of distal tip cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of distal tip cell migration" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:1903354 ! regulation of distal tip cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097628 ! distal tip cell migration +relationship: positively_regulates GO:0097628 ! distal tip cell migration +created_by: pr +creation_date: 2014-08-21T10:05:26Z + +[Term] +id: GO:1903357 +name: regulation of transcription initiation from RNA polymerase I promoter +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter." [GO_REF:0000058, GOC:TermGenie, PMID:9092673] +synonym: "regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript" NARROW [] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +is_a: GO:2000142 ! regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006361 ! transcription initiation from RNA polymerase I promoter +relationship: regulates GO:0006361 ! transcription initiation from RNA polymerase I promoter +created_by: mah +creation_date: 2014-08-21T10:19:32Z + +[Term] +id: GO:1903358 +name: regulation of Golgi organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788] +synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie] +synonym: "regulation of Golgi organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007030 ! Golgi organization +relationship: regulates GO:0007030 ! Golgi organization +created_by: als +creation_date: 2014-08-21T10:22:22Z + +[Term] +id: GO:1903359 +name: lateral cortical node assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node." [GO_REF:0000079, GOC:TermGenie, PMID:25009287] +synonym: "lateral cortical node formation" EXACT [GOC:TermGenie] +synonym: "Skb1-containing cortical node assembly" EXACT [GOC:TermGenie] +synonym: "Skb1-containing cortical node formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2014-08-21T10:22:51Z + +[Term] +id: GO:1903360 +name: protein localization to lateral cortical node +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a lateral cortical node." [GO_REF:0000087, GOC:TermGenie, PMID:25009287] +synonym: "protein localisation in lateral cortical node" EXACT [GOC:TermGenie] +synonym: "protein localisation to lateral cortical node" EXACT [GOC:TermGenie] +synonym: "protein localization in lateral cortical node" EXACT [GOC:TermGenie] +is_a: GO:0072697 ! protein localization to cell cortex +created_by: mah +creation_date: 2014-08-21T10:23:00Z + +[Term] +id: GO:1903361 +name: protein localization to basolateral plasma membrane +namespace: biological_process +alt_id: GO:0061467 +def: "Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:24785082, PMID:9425351] +synonym: "basolateral protein localization" EXACT [] +synonym: "protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery +created_by: dph +creation_date: 2012-10-19T13:58:04Z + +[Term] +id: GO:1903362 +name: regulation of cellular protein catabolic process +namespace: biological_process +alt_id: GO:2000598 +def: "Any process that modulates the frequency, rate or extent of cellular protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] +synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of cyclin breakdown" NARROW [GOC:obol] +synonym: "regulation of cyclin catabolic process" NARROW [] +synonym: "regulation of cyclin catabolism" NARROW [GOC:obol] +synonym: "regulation of cyclin degradation" NARROW [GOC:obol] +synonym: "regulation of degradation of cyclin" NARROW [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0032268 ! regulation of cellular protein metabolic process +is_a: GO:0042176 ! regulation of protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044257 ! cellular protein catabolic process +relationship: regulates GO:0044257 ! cellular protein catabolic process +created_by: kmv +creation_date: 2014-08-21T15:05:45Z + +[Term] +id: GO:1903363 +name: negative regulation of cellular protein catabolic process +namespace: biological_process +alt_id: GO:2000599 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] +synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular protein breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclin breakdown" NARROW [GOC:obol] +synonym: "negative regulation of cyclin catabolic process" NARROW [] +synonym: "negative regulation of cyclin catabolism" NARROW [GOC:obol] +synonym: "negative regulation of cyclin degradation" NARROW [GOC:obol] +synonym: "negative regulation of degradation of cyclin" NARROW [GOC:obol] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0032269 ! negative regulation of cellular protein metabolic process +is_a: GO:0042177 ! negative regulation of protein catabolic process +is_a: GO:1903362 ! regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044257 ! cellular protein catabolic process +relationship: negatively_regulates GO:0044257 ! cellular protein catabolic process +created_by: kmv +creation_date: 2014-08-21T15:05:53Z + +[Term] +id: GO:1903364 +name: positive regulation of cellular protein catabolic process +namespace: biological_process +alt_id: GO:2000600 +def: "Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] +synonym: "activation of cellular protein breakdown" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of cyclin breakdown" NARROW [GOC:obol] +synonym: "positive regulation of cyclin catabolic process" NARROW [] +synonym: "positive regulation of cyclin catabolism" NARROW [GOC:obol] +synonym: "positive regulation of cyclin degradation" NARROW [GOC:obol] +synonym: "positive regulation of degradation of cyclin" NARROW [GOC:obol] +synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0032270 ! positive regulation of cellular protein metabolic process +is_a: GO:0045732 ! positive regulation of protein catabolic process +is_a: GO:1903362 ! regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044257 ! cellular protein catabolic process +relationship: positively_regulates GO:0044257 ! cellular protein catabolic process +created_by: kmv +creation_date: 2014-08-21T15:06:01Z + +[Term] +id: GO:1903365 +name: regulation of fear response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fear response." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +synonym: "regulation of physiological fear response" EXACT [GOC:TermGenie] +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042596 ! fear response +relationship: regulates GO:0042596 ! fear response +created_by: mr +creation_date: 2014-08-21T23:21:36Z + +[Term] +id: GO:1903366 +name: negative regulation of fear response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fear response." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +synonym: "down regulation of fear response" EXACT [GOC:TermGenie] +synonym: "down regulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "down-regulation of fear response" EXACT [GOC:TermGenie] +synonym: "down-regulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "downregulation of fear response" EXACT [GOC:TermGenie] +synonym: "downregulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "inhibition of fear response" NARROW [GOC:TermGenie] +synonym: "inhibition of physiological fear response" NARROW [GOC:TermGenie] +synonym: "negative regulation of physiological fear response" EXACT [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903365 ! regulation of fear response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042596 ! fear response +relationship: negatively_regulates GO:0042596 ! fear response +created_by: mr +creation_date: 2014-08-21T23:21:45Z + +[Term] +id: GO:1903367 +name: positive regulation of fear response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fear response." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +synonym: "activation of fear response" NARROW [GOC:TermGenie] +synonym: "activation of physiological fear response" NARROW [GOC:TermGenie] +synonym: "positive regulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "up regulation of fear response" EXACT [GOC:TermGenie] +synonym: "up regulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "up-regulation of fear response" EXACT [GOC:TermGenie] +synonym: "up-regulation of physiological fear response" EXACT [GOC:TermGenie] +synonym: "upregulation of fear response" EXACT [GOC:TermGenie] +synonym: "upregulation of physiological fear response" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903365 ! regulation of fear response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042596 ! fear response +relationship: positively_regulates GO:0042596 ! fear response +created_by: mr +creation_date: 2014-08-21T23:21:53Z + +[Term] +id: GO:1903368 +name: regulation of foraging behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of foraging behavior." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060756 ! foraging behavior +relationship: regulates GO:0060756 ! foraging behavior +created_by: mr +creation_date: 2014-08-22T03:03:04Z + +[Term] +id: GO:1903369 +name: negative regulation of foraging behavior +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +synonym: "down regulation of foraging behavior" EXACT [GOC:TermGenie] +synonym: "down-regulation of foraging behavior" EXACT [GOC:TermGenie] +synonym: "downregulation of foraging behavior" EXACT [GOC:TermGenie] +synonym: "inhibition of foraging behavior" NARROW [GOC:TermGenie] +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:1903368 ! regulation of foraging behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060756 ! foraging behavior +relationship: negatively_regulates GO:0060756 ! foraging behavior +created_by: mr +creation_date: 2014-08-22T03:03:12Z + +[Term] +id: GO:1903370 +name: positive regulation of foraging behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of foraging behavior." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:8677262] +synonym: "activation of foraging behavior" NARROW [GOC:TermGenie] +synonym: "up regulation of foraging behavior" EXACT [GOC:TermGenie] +synonym: "up-regulation of foraging behavior" EXACT [GOC:TermGenie] +synonym: "upregulation of foraging behavior" EXACT [GOC:TermGenie] +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:1903368 ! regulation of foraging behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060756 ! foraging behavior +relationship: positively_regulates GO:0060756 ! foraging behavior +created_by: mr +creation_date: 2014-08-22T03:03:20Z + +[Term] +id: GO:1903371 +name: regulation of endoplasmic reticulum tubular network organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24891604] +synonym: "regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "regulation of ER tubular network organization" EXACT [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071786 ! endoplasmic reticulum tubular network organization +relationship: regulates GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: als +creation_date: 2014-08-22T11:01:14Z + +[Term] +id: GO:1903372 +name: negative regulation of endoplasmic reticulum tubular network organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24891604] +synonym: "down regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "down regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "downregulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum tubular network organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum tubular network organization" NARROW [GOC:TermGenie] +synonym: "inhibition of ER tubular network organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of ER tubular network organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER tubular network organization" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1903371 ! regulation of endoplasmic reticulum tubular network organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071786 ! endoplasmic reticulum tubular network organization +relationship: negatively_regulates GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: als +creation_date: 2014-08-22T11:01:23Z + +[Term] +id: GO:1903373 +name: positive regulation of endoplasmic reticulum tubular network organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24891604] +synonym: "activation of endoplasmic reticulum tubular network organisation" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum tubular network organization" NARROW [GOC:TermGenie] +synonym: "activation of ER tubular network organisation" NARROW [GOC:TermGenie] +synonym: "activation of ER tubular network organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "up regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER tubular network organization" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum tubular network organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum tubular network organization" EXACT [GOC:TermGenie] +synonym: "upregulation of ER tubular network organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of ER tubular network organization" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1903371 ! regulation of endoplasmic reticulum tubular network organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071786 ! endoplasmic reticulum tubular network organization +relationship: positively_regulates GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: als +creation_date: 2014-08-22T11:01:31Z + +[Term] +id: GO:1903374 +name: subarachnoid space development +namespace: biological_process +def: "The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure." [GO_REF:0000094, GOC:cjm, GOC:TermGenie, Wikipedia:Subarachnoid_space] +synonym: "cavitas subarachnoidea development" RELATED [GOC:TermGenie] +synonym: "cavum subarachnoideale development" RELATED [GOC:TermGenie] +synonym: "spatium leptomeningeum development" RELATED [GOC:TermGenie] +synonym: "spatium subarachnoideum development" RELATED [GOC:TermGenie] +synonym: "subarachnoid cavity development" RELATED [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0007420 ! brain development +created_by: pr +creation_date: 2014-08-22T12:20:56Z + +[Term] +id: GO:1903375 +name: facioacoustic ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] +synonym: "acoustico-facial VII-VIII ganglion complex development" EXACT [UBERON:0012175] +synonym: "acousticofacial ganglion development" EXACT [GOC:TermGenie] +synonym: "facio-acoustic ganglion complex VII-VIII development" EXACT [GOC:TermGenie] +synonym: "facio-acoustic ganglion development" EXACT [GOC:TermGenie] +synonym: "facio-acoustic VII-VIII ganglion complex development" EXACT [GOC:TermGenie] +is_a: GO:0061550 ! cranial ganglion development +created_by: bf +creation_date: 2014-08-26T12:40:36Z + +[Term] +id: GO:1903376 +name: regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [] +synonym: "regulation of oxidative stress-induced neuron apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of oxidative stress-induced neuronal apoptosis" BROAD [GOC:TermGenie] +is_a: GO:0043523 ! regulation of neuron apoptotic process +is_a: GO:1902175 ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903203 ! regulation of oxidative stress-induced neuron death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: bf +creation_date: 2014-08-26T13:03:13Z + +[Term] +id: GO:1903377 +name: negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:15790595] +synonym: "down regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "down-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "inhibition of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [] +synonym: "negative regulation of oxidative stress-induced neuron apoptosis" EXACT [GOC:bf] +synonym: "neuroprotection against oxidative stress-induced apoptosis" RELATED [GOC:bf] +synonym: "protection against oxidative stress-induced neuron apoptosis" RELATED [GOC:bf] +synonym: "protection against oxidative stress-induced neuronal apoptosis" RELATED [GOC:bf] +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +is_a: GO:1902176 ! negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903204 ! negative regulation of oxidative stress-induced neuron death +is_a: GO:1903376 ! regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: negatively_regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: bf +creation_date: 2014-08-26T13:03:28Z + +[Term] +id: GO:1903378 +name: positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [] +synonym: "up regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of neuron apoptosis in response to oxidative stress" RELATED [GOC:TermGenie] +synonym: "upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress" EXACT [GOC:TermGenie] +is_a: GO:0043525 ! positive regulation of neuron apoptotic process +is_a: GO:1902177 ! positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903223 ! positive regulation of oxidative stress-induced neuron death +is_a: GO:1903376 ! regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +relationship: positively_regulates GO:0036480 ! neuron intrinsic apoptotic signaling pathway in response to oxidative stress +created_by: bf +creation_date: 2014-08-26T13:03:36Z + +[Term] +id: GO:1903379 +name: regulation of mitotic chromosome condensation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0060623 ! regulation of chromosome condensation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007076 ! mitotic chromosome condensation +relationship: regulates GO:0007076 ! mitotic chromosome condensation +created_by: al +creation_date: 2014-08-26T13:57:13Z + +[Term] +id: GO:1903380 +name: positive regulation of mitotic chromosome condensation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] +synonym: "activation of mitotic chromosome condensation" NARROW [GOC:TermGenie] +synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +is_a: GO:1903379 ! regulation of mitotic chromosome condensation +is_a: GO:1905821 ! positive regulation of chromosome condensation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007076 ! mitotic chromosome condensation +relationship: positively_regulates GO:0007076 ! mitotic chromosome condensation +created_by: al +creation_date: 2014-08-26T13:57:29Z + +[Term] +id: GO:1903381 +name: regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum stress-induced neuron apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of ER stress-induced neuron apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [] +is_a: GO:0043523 ! regulation of neuron apoptotic process +is_a: GO:1902235 ! regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036483 ! neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: regulates GO:0036483 ! neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2014-08-27T08:45:29Z + +[Term] +id: GO:1903382 +name: negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23453807] +synonym: "down regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of ER stress-induced neuron intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" EXACT [] +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +is_a: GO:1902236 ! negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903381 ! regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036483 ! neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +relationship: negatively_regulates GO:0036483 ! neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2014-08-27T08:45:38Z + +[Term] +id: GO:1903383 +name: regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of H2O2-induced neuron apoptosis" BROAD [GOC:bf] +synonym: "regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen peroxide-induced neuron apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of hydrogen peroxide-induced neuronal apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [] +is_a: GO:1903207 ! regulation of hydrogen peroxide-induced neuron death +is_a: GO:1903376 ! regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +is_a: GO:1903750 ! regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036482 ! neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: regulates GO:0036482 ! neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide +created_by: bf +creation_date: 2014-08-27T08:50:37Z + +[Term] +id: GO:1903384 +name: negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23261939] +synonym: "down regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "down regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "down-regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "downregulation of H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "downregulation of neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "downregulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "inhibition of H2O2-induced neuron intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "inhibition of neuron intrinsic apoptotic signaling pathway in response to H2O2" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "negative regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuron apoptosis in response to hydrogen peroxide" RELATED [GOC:TermGenie] +synonym: "negative regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [] +synonym: "protection against H2O2-induced neuron apoptosis" RELATED [GOC:bf] +synonym: "protection against hydrogen peroxide-induced neuron apoptosis" RELATED [GOC:bf] +is_a: GO:1903208 ! negative regulation of hydrogen peroxide-induced neuron death +is_a: GO:1903377 ! negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway +is_a: GO:1903383 ! regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway +is_a: GO:1903751 ! negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036482 ! neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: negatively_regulates GO:0036482 ! neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide +created_by: bf +creation_date: 2014-08-27T08:50:45Z + +[Term] +id: GO:1903385 +name: regulation of homophilic cell adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of homophilic cell adhesion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +relationship: regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +created_by: als +creation_date: 2014-08-27T09:57:30Z + +[Term] +id: GO:1903386 +name: negative regulation of homophilic cell adhesion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +synonym: "down regulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +synonym: "downregulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +synonym: "inhibition of homophilic cell adhesion" NARROW [GOC:TermGenie] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:1903385 ! regulation of homophilic cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +relationship: negatively_regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +created_by: als +creation_date: 2014-08-27T09:57:38Z + +[Term] +id: GO:1903387 +name: positive regulation of homophilic cell adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +synonym: "activation of homophilic cell adhesion" NARROW [GOC:TermGenie] +synonym: "up regulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +synonym: "upregulation of homophilic cell adhesion" EXACT [GOC:TermGenie] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:1903385 ! regulation of homophilic cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +relationship: positively_regulates GO:0007156 ! homophilic cell adhesion via plasma membrane adhesion molecules +created_by: als +creation_date: 2014-08-27T09:57:46Z + +[Term] +id: GO:1903388 +name: regulation of synaptic vesicle uncoating +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21563316] +synonym: "regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +is_a: GO:1900242 ! regulation of synaptic vesicle endocytosis +is_a: GO:1901879 ! regulation of protein depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016191 ! synaptic vesicle uncoating +relationship: regulates GO:0016191 ! synaptic vesicle uncoating +created_by: pad +creation_date: 2014-08-27T10:02:53Z + +[Term] +id: GO:1903389 +name: negative regulation of synaptic vesicle uncoating +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21563316] +synonym: "down regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle coat depolymerization" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle coat protein depolymerization" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle uncoating" NARROW [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "negative regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +is_a: GO:1900243 ! negative regulation of synaptic vesicle endocytosis +is_a: GO:1901880 ! negative regulation of protein depolymerization +is_a: GO:1903388 ! regulation of synaptic vesicle uncoating +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016191 ! synaptic vesicle uncoating +relationship: negatively_regulates GO:0016191 ! synaptic vesicle uncoating +created_by: pad +creation_date: 2014-08-27T10:03:02Z + +[Term] +id: GO:1903390 +name: positive regulation of synaptic vesicle uncoating +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21563316] +synonym: "activation of synaptic vesicle coat depolymerization" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle coat protein depolymerization" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle uncoating" NARROW [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "positive regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle coat depolymerization" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle coat protein depolymerization" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle uncoating" EXACT [GOC:TermGenie] +is_a: GO:1900244 ! positive regulation of synaptic vesicle endocytosis +is_a: GO:1901881 ! positive regulation of protein depolymerization +is_a: GO:1903388 ! regulation of synaptic vesicle uncoating +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016191 ! synaptic vesicle uncoating +relationship: positively_regulates GO:0016191 ! synaptic vesicle uncoating +created_by: pad +creation_date: 2014-08-27T10:03:10Z + +[Term] +id: GO:1903391 +name: regulation of adherens junction organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adherens junction organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +synonym: "regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "regulation of adherens junction organisation" EXACT [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0034332 ! adherens junction organization +relationship: regulates GO:0034332 ! adherens junction organization +created_by: als +creation_date: 2014-08-27T10:08:38Z + +[Term] +id: GO:1903392 +name: negative regulation of adherens junction organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +synonym: "down regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "down regulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of adherens junction organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of adherens junction organization" EXACT [GOC:TermGenie] +synonym: "downregulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of adherens junction organization" EXACT [GOC:TermGenie] +synonym: "inhibition of adherens junction assembly and maintenance" NARROW [GOC:TermGenie] +synonym: "inhibition of adherens junction organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of adherens junction organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "negative regulation of adherens junction organisation" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903391 ! regulation of adherens junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0034332 ! adherens junction organization +relationship: negatively_regulates GO:0034332 ! adherens junction organization +created_by: als +creation_date: 2014-08-27T10:08:47Z + +[Term] +id: GO:1903393 +name: positive regulation of adherens junction organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adherens junction organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:21724833] +synonym: "activation of adherens junction assembly and maintenance" NARROW [GOC:TermGenie] +synonym: "activation of adherens junction organisation" NARROW [GOC:TermGenie] +synonym: "activation of adherens junction organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "positive regulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "up regulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of adherens junction organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "up-regulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of adherens junction organization" EXACT [GOC:TermGenie] +synonym: "upregulation of adherens junction assembly and maintenance" EXACT [GOC:TermGenie] +synonym: "upregulation of adherens junction organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of adherens junction organization" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903391 ! regulation of adherens junction organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0034332 ! adherens junction organization +relationship: positively_regulates GO:0034332 ! adherens junction organization +created_by: als +creation_date: 2014-08-27T10:08:55Z + +[Term] +id: GO:1903394 +name: protein localization to kinetochore involved in kinetochore assembly +namespace: biological_process +def: "Any protein localization to kinetochore that is involved in kinetochore assembly." [GO_REF:0000060, GOC:TermGenie, PMID:15369671] +synonym: "condensin localization to kinetochore involved in centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "condensin localization to kinetochore involved in centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "condensin localization to kinetochore involved in chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "condensin localization to kinetochore involved in kinetochore assembly" NARROW [GOC:TermGenie] +synonym: "condensin localization to kinetochore involved in kinetochore formation" RELATED [GOC:TermGenie] +synonym: "protein localisation to kinetochore involved in centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "protein localisation to kinetochore involved in centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "protein localisation to kinetochore involved in chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "protein localisation to kinetochore involved in kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "protein localisation to kinetochore involved in kinetochore formation" RELATED [GOC:TermGenie] +synonym: "protein localization to kinetochore involved in centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "protein localization to kinetochore involved in centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "protein localization to kinetochore involved in chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "protein localization to kinetochore involved in kinetochore formation" RELATED [GOC:TermGenie] +is_a: GO:0034501 ! protein localization to kinetochore +intersection_of: GO:0034501 ! protein localization to kinetochore +intersection_of: part_of GO:0051382 ! kinetochore assembly +relationship: part_of GO:0051382 ! kinetochore assembly +created_by: vw +creation_date: 2014-08-29T13:11:55Z + +[Term] +id: GO:1903395 +name: regulation of secondary cell septum biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23878277] +is_a: GO:0140279 ! regulation of mitotic division septum assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1990344 ! secondary cell septum biogenesis +relationship: regulates GO:1990344 ! secondary cell septum biogenesis +created_by: di +creation_date: 2014-08-29T21:42:17Z + +[Term] +id: GO:1903396 +name: negative regulation of secondary cell septum biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23878277] +synonym: "down regulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of secondary cell septum biogenesis" NARROW [GOC:TermGenie] +is_a: GO:0140280 ! negative regulation of mitotic division septum assembly +is_a: GO:1903395 ! regulation of secondary cell septum biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990344 ! secondary cell septum biogenesis +relationship: negatively_regulates GO:1990344 ! secondary cell septum biogenesis +created_by: di +creation_date: 2014-08-29T21:42:26Z + +[Term] +id: GO:1903397 +name: positive regulation of secondary cell septum biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:23878277] +synonym: "activation of secondary cell septum biogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of secondary cell septum biogenesis" EXACT [GOC:TermGenie] +is_a: GO:0140281 ! positive regulation of mitotic division septum assembly +is_a: GO:1903395 ! regulation of secondary cell septum biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990344 ! secondary cell septum biogenesis +relationship: positively_regulates GO:1990344 ! secondary cell septum biogenesis +created_by: di +creation_date: 2014-08-29T21:42:34Z + +[Term] +id: GO:1903398 +name: regulation of m7G(5')pppN diphosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:22323607] +synonym: "regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of decapase activity" RELATED [GOC:TermGenie] +synonym: "regulation of M(7)G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of m7G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050072 ! m7G(5')pppN diphosphatase activity +relationship: regulates GO:0050072 ! m7G(5')pppN diphosphatase activity +created_by: mah +creation_date: 2014-09-01T10:16:40Z + +[Term] +id: GO:1903399 +name: positive regulation of m7G(5')pppN diphosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:22323607] +synonym: "activation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of decapase activity" RELATED [GOC:TermGenie] +synonym: "activation of M(7)G(5')pppN pyrophosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of m7G(5')pppN diphosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of m7G(5')pppN pyrophosphatase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of decapase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of M(7)G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of m7G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of decapase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of M(7)G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of m7G(5')pppN diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of m7G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of decapase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of M(7)G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of m7G(5')pppN diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of m7G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of decapase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of M(7)G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of m7G(5')pppN diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of m7G(5')pppN pyrophosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903398 ! regulation of m7G(5')pppN diphosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050072 ! m7G(5')pppN diphosphatase activity +relationship: positively_regulates GO:0050072 ! m7G(5')pppN diphosphatase activity +created_by: mah +creation_date: 2014-09-01T10:16:49Z + +[Term] +id: GO:1903400 +name: L-arginine transmembrane transport +namespace: biological_process +def: "The directed movement of L-arginine across a membrane." [GO_REF:0000069, GOC:krc, GOC:TermGenie, PMID:8195186] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:1902023 ! L-arginine transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +is_a: GO:1903826 ! arginine transmembrane transport +created_by: pr +creation_date: 2014-09-01T13:45:48Z + +[Term] +id: GO:1903401 +name: L-lysine transmembrane transport +namespace: biological_process +def: "The directed movement of L-lysine across a membrane." [GO_REF:0000069, GOC:krc, GOC:TermGenie, PMID:8195186] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902022 ! L-lysine transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: pr +creation_date: 2014-09-01T13:45:56Z + +[Term] +id: GO:1903402 +name: regulation of renal phosphate excretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of renal phosphate excretion." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:8700837] +synonym: "regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +is_a: GO:0044062 ! regulation of excretion +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044722 ! renal phosphate excretion +relationship: regulates GO:0044722 ! renal phosphate excretion +created_by: pm +creation_date: 2014-09-01T13:47:01Z + +[Term] +id: GO:1903403 +name: negative regulation of renal phosphate excretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:8700837] +synonym: "down regulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "down regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "downregulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "downregulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "inhibition of renal phosphate excretion" NARROW [GOC:TermGenie] +synonym: "inhibition of renal phosphate ion excretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903402 ! regulation of renal phosphate excretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044722 ! renal phosphate excretion +relationship: negatively_regulates GO:0044722 ! renal phosphate excretion +created_by: pm +creation_date: 2014-09-01T13:47:10Z + +[Term] +id: GO:1903404 +name: positive regulation of renal phosphate excretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of renal phosphate excretion." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:8700837] +synonym: "activation of renal phosphate excretion" NARROW [GOC:TermGenie] +synonym: "activation of renal phosphate ion excretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "up regulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "up regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +synonym: "upregulation of renal phosphate excretion" EXACT [GOC:TermGenie] +synonym: "upregulation of renal phosphate ion excretion" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903402 ! regulation of renal phosphate excretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044722 ! renal phosphate excretion +relationship: positively_regulates GO:0044722 ! renal phosphate excretion +created_by: pm +creation_date: 2014-09-01T13:47:18Z + +[Term] +id: GO:1903405 +name: protein localization to nuclear body +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a nuclear body." [GO_REF:0000087, GOC:TermGenie, PMID:24713849] +synonym: "protein localisation in nuclear body" EXACT [GOC:TermGenie] +synonym: "protein localisation to nuclear body" EXACT [GOC:TermGenie] +synonym: "protein localization in nuclear body" EXACT [GOC:TermGenie] +is_a: GO:1990173 ! protein localization to nucleoplasm +created_by: mah +creation_date: 2014-09-01T13:57:11Z + +[Term] +id: GO:1903406 +name: regulation of sodium:potassium-exchanging ATPase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] +synonym: "regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "regulation of sodium pump" BROAD [GOC:TermGenie] +synonym: "regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +relationship: regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +created_by: mr +creation_date: 2014-09-02T19:45:08Z + +[Term] +id: GO:1903407 +name: negative regulation of sodium:potassium-exchanging ATPase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] +synonym: "down regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "down regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "down regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "down regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "down-regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "down-regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "downregulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "downregulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "downregulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of (Na+ + K+)-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of (Na+ + K+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP phosphohydrolase (Na+/K+-exchanging)" NARROW [GOC:TermGenie] +synonym: "inhibition of Na(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "inhibition of Na+,K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na+/K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na,K-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "inhibition of sodium/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium/potassium-transporting ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sodium:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "negative regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "negative regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity +is_a: GO:1903406 ! regulation of sodium:potassium-exchanging ATPase activity +is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +relationship: negatively_regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +created_by: mr +creation_date: 2014-09-02T19:45:16Z + +[Term] +id: GO:1903408 +name: positive regulation of sodium:potassium-exchanging ATPase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] +synonym: "activation of (Na+ + K+)-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of (Na+ + K+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP phosphohydrolase (Na+/K+-exchanging)" NARROW [GOC:TermGenie] +synonym: "activation of Na(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "activation of Na+,K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na+/K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na,K-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "activation of sodium/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of sodium/potassium-transporting ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of sodium:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of sodium:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "positive regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "positive regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "up regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "up regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "up regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "up-regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "up-regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "upregulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na+,K+ pump" RELATED [GOC:TermGenie] +synonym: "upregulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Na,K-pump" RELATED [GOC:TermGenie] +synonym: "upregulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity +is_a: GO:1903406 ! regulation of sodium:potassium-exchanging ATPase activity +is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +relationship: positively_regulates GO:0005391 ! sodium:potassium-exchanging ATPase activity +created_by: mr +creation_date: 2014-09-02T19:45:24Z + +[Term] +id: GO:1903409 +name: reactive oxygen species biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "reactive oxygen species generation" RELATED [PMID:24252804] +synonym: "reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "ROS formation" RELATED [] +synonym: "ROS generation" RELATED [PMID:24252804] +is_a: GO:0009058 ! biosynthetic process +is_a: GO:0072593 ! reactive oxygen species metabolic process +created_by: bf +creation_date: 2014-09-03T09:19:13Z + +[Term] +id: GO:1903412 +name: response to bile acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: rl +creation_date: 2014-09-03T12:45:43Z + +[Term] +id: GO:1903413 +name: cellular response to bile acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1903412 ! response to bile acid +created_by: rl +creation_date: 2014-09-03T12:45:51Z + +[Term] +id: GO:1903415 +name: flavonoid transport from endoplasmic reticulum to plant-type vacuole +namespace: biological_process +def: "The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole." [GO_REF:0000078, GOC:tb, GOC:TermGenie, PMID:25116949] +synonym: "flavonoid accumulation in vacuole" RELATED [] +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0071702 ! organic substance transport +created_by: tb +creation_date: 2014-09-05T00:35:34Z + +[Term] +id: GO:1903416 +name: response to glycoside +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus." [GO_REF:0000071, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:12027881, PMID:16243970] +synonym: "cellular response to ouabain" RELATED [CHEBI:472805] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: rl +creation_date: 2014-09-05T12:41:01Z + +[Term] +id: GO:1903418 +name: protein localization to plasma membrane of cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip." [GO_REF:0000087, GOC:TermGenie, PMID:25157670, PMID:27852900] +synonym: "protein localisation in plasma membrane of cell tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to plasma membrane of cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization in plasma membrane of cell tip" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990151 ! protein localization to cell tip +is_a: GO:1990778 ! protein localization to cell periphery +created_by: mah +creation_date: 2014-09-08T15:08:51Z + +[Term] +id: GO:1903419 +name: protein localization to cortical endoplasmic reticulum +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum." [GO_REF:0000087, GOC:TermGenie, PMID:25103238] +synonym: "protein localisation in cortical endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "protein localisation to cortical endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "protein localization in cortical endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "protein localization to cortical ER" EXACT [] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:1903420 ! protein localization to endoplasmic reticulum tubular network +created_by: mah +creation_date: 2014-09-08T16:03:28Z + +[Term] +id: GO:1903420 +name: protein localization to endoplasmic reticulum tubular network +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network." [GO_REF:0000087, GOC:TermGenie, PMID:25103238] +synonym: "protein localisation in endoplasmic reticulum tubular network" EXACT [GOC:TermGenie] +synonym: "protein localisation to endoplasmic reticulum tubular network" EXACT [GOC:TermGenie] +synonym: "protein localization in endoplasmic reticulum tubular network" EXACT [GOC:TermGenie] +synonym: "protein localization to tubular ER" RELATED [PMID:25103238] +is_a: GO:0070972 ! protein localization to endoplasmic reticulum +created_by: mah +creation_date: 2014-09-08T16:03:37Z + +[Term] +id: GO:1903421 +name: regulation of synaptic vesicle recycling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle recycling." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22745285] +comment: An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype +synonym: "regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +is_a: GO:0098693 ! regulation of synaptic vesicle cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036465 ! synaptic vesicle recycling +relationship: regulates GO:0036465 ! synaptic vesicle recycling +created_by: pad +creation_date: 2014-09-09T15:27:50Z + +[Term] +id: GO:1903422 +name: negative regulation of synaptic vesicle recycling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22745285] +comment: An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype +synonym: "down regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "down regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "down regulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +synonym: "down-regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "down-regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "down-regulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +synonym: "downregulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "downregulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "downregulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +synonym: "inhibition of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "inhibition of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "negative regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "negative regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1903421 ! regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036465 ! synaptic vesicle recycling +relationship: negatively_regulates GO:0036465 ! synaptic vesicle recycling +created_by: pad +creation_date: 2014-09-09T15:27:59Z + +[Term] +id: GO:1903423 +name: positive regulation of synaptic vesicle recycling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22745285] +comment: An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype +synonym: "activation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "activation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "activation of synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "positive regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "positive regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "up regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "up regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "up regulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +synonym: "up-regulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "up-regulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "up-regulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +synonym: "upregulation of kiss-and-run synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "upregulation of kiss-and-stay synaptic vesicle recycling" NARROW [GOC:TermGenie] +synonym: "upregulation of synaptic vesicle recycling" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1903421 ! regulation of synaptic vesicle recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036465 ! synaptic vesicle recycling +relationship: positively_regulates GO:0036465 ! synaptic vesicle recycling +created_by: pad +creation_date: 2014-09-09T15:28:07Z + +[Term] +id: GO:1903424 +name: fluoride transmembrane transport +namespace: biological_process +def: "The process in which fluoride is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:24173035] +synonym: "fluoride membrane transport" EXACT [] +synonym: "transmembrane fluoride transport" EXACT [] +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: mcc +creation_date: 2014-09-09T21:21:01Z + +[Term] +id: GO:1903425 +name: fluoride transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of fluoride from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, PMID:24173035] +is_a: GO:0015103 ! inorganic anion transmembrane transporter activity +relationship: part_of GO:1903424 ! fluoride transmembrane transport +created_by: mcc +creation_date: 2014-09-09T21:27:55Z + +[Term] +id: GO:1903426 +name: regulation of reactive oxygen species biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "regulation of ROS generation" RELATED [GOC:TermGenie] +is_a: GO:0009889 ! regulation of biosynthetic process +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903409 ! reactive oxygen species biosynthetic process +relationship: regulates GO:1903409 ! reactive oxygen species biosynthetic process +created_by: bf +creation_date: 2014-09-11T10:01:47Z + +[Term] +id: GO:1903427 +name: negative regulation of reactive oxygen species biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "down regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "down regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "down regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "down regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "down-regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "downregulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "downregulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species formation" NARROW [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "inhibition of reactive oxygen species synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of ROS formation" RELATED [GOC:TermGenie] +synonym: "inhibition of ROS generation" RELATED [GOC:TermGenie] +synonym: "negative regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "negative regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "prevention of ROS generation" EXACT [PMID:24252804] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process +is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903409 ! reactive oxygen species biosynthetic process +relationship: negatively_regulates GO:1903409 ! reactive oxygen species biosynthetic process +created_by: bf +creation_date: 2014-09-11T10:01:56Z + +[Term] +id: GO:1903428 +name: positive regulation of reactive oxygen species biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804] +synonym: "activation of reactive oxygen species anabolism" NARROW [GOC:TermGenie] +synonym: "activation of reactive oxygen species biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of reactive oxygen species biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of reactive oxygen species formation" NARROW [GOC:TermGenie] +synonym: "activation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "activation of reactive oxygen species synthesis" NARROW [GOC:TermGenie] +synonym: "activation of ROS formation" RELATED [GOC:TermGenie] +synonym: "activation of ROS generation" RELATED [GOC:TermGenie] +synonym: "positive regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "positive regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "up regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "up regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "up-regulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of ROS generation" RELATED [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species formation" EXACT [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species generation" RELATED [GOC:TermGenie] +synonym: "upregulation of reactive oxygen species synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ROS formation" RELATED [GOC:TermGenie] +synonym: "upregulation of ROS generation" RELATED [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:1903426 ! regulation of reactive oxygen species biosynthetic process +is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903409 ! reactive oxygen species biosynthetic process +relationship: positively_regulates GO:1903409 ! reactive oxygen species biosynthetic process +created_by: bf +creation_date: 2014-09-11T10:02:05Z + +[Term] +id: GO:1903429 +name: regulation of cell maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] +synonym: "regulation of functional differentiation" RELATED [GOC:TermGenie] +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048469 ! cell maturation +relationship: regulates GO:0048469 ! cell maturation +created_by: jl +creation_date: 2014-09-15T13:31:23Z + +[Term] +id: GO:1903430 +name: negative regulation of cell maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] +synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "down regulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "inhibition of cell maturation" NARROW [GOC:TermGenie] +synonym: "inhibition of functional differentiation" RELATED [GOC:TermGenie] +synonym: "negative regulation of functional differentiation" RELATED [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:1903429 ! regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048469 ! cell maturation +relationship: negatively_regulates GO:0048469 ! cell maturation +created_by: jl +creation_date: 2014-09-15T13:31:32Z + +[Term] +id: GO:1903431 +name: positive regulation of cell maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] +synonym: "activation of cell maturation" NARROW [GOC:TermGenie] +synonym: "activation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "up regulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of functional differentiation" RELATED [GOC:TermGenie] +synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of functional differentiation" RELATED [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:1903429 ! regulation of cell maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048469 ! cell maturation +relationship: positively_regulates GO:0048469 ! cell maturation +created_by: jl +creation_date: 2014-09-15T13:31:41Z + +[Term] +id: GO:1903432 +name: regulation of TORC1 signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of TORC1 signaling." [GO_REF:0000058, GOC:TermGenie] +synonym: "regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +is_a: GO:0032006 ! regulation of TOR signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038202 ! TORC1 signaling +relationship: regulates GO:0038202 ! TORC1 signaling +created_by: jl +creation_date: 2014-09-15T13:35:39Z + +[Term] +id: GO:1903433 +name: regulation of constitutive secretory pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of constitutive secretory pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22899725] +is_a: GO:0017157 ! regulation of exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045054 ! constitutive secretory pathway +relationship: regulates GO:0045054 ! constitutive secretory pathway +created_by: als +creation_date: 2014-09-15T15:07:31Z + +[Term] +id: GO:1903434 +name: negative regulation of constitutive secretory pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22899725] +synonym: "down regulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of constitutive secretory pathway" NARROW [GOC:TermGenie] +is_a: GO:0045920 ! negative regulation of exocytosis +is_a: GO:1903433 ! regulation of constitutive secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045054 ! constitutive secretory pathway +relationship: negatively_regulates GO:0045054 ! constitutive secretory pathway +created_by: als +creation_date: 2014-09-15T15:07:40Z + +[Term] +id: GO:1903435 +name: positive regulation of constitutive secretory pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22899725] +synonym: "activation of constitutive secretory pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of constitutive secretory pathway" EXACT [GOC:TermGenie] +is_a: GO:0045921 ! positive regulation of exocytosis +is_a: GO:1903433 ! regulation of constitutive secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045054 ! constitutive secretory pathway +relationship: positively_regulates GO:0045054 ! constitutive secretory pathway +created_by: als +creation_date: 2014-09-15T15:07:48Z + +[Term] +id: GO:1903436 +name: regulation of mitotic cytokinetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cytokinetic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0032954 ! regulation of cytokinetic process +is_a: GO:1902412 ! regulation of mitotic cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902410 ! mitotic cytokinetic process +relationship: regulates GO:1902410 ! mitotic cytokinetic process +created_by: tb +creation_date: 2014-09-15T23:11:38Z + +[Term] +id: GO:1903437 +name: negative regulation of mitotic cytokinetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic cytokinetic process" NARROW [GOC:TermGenie] +is_a: GO:1902413 ! negative regulation of mitotic cytokinesis +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902410 ! mitotic cytokinetic process +relationship: negatively_regulates GO:1902410 ! mitotic cytokinetic process +created_by: tb +creation_date: 2014-09-15T23:11:47Z + +[Term] +id: GO:1903438 +name: positive regulation of mitotic cytokinetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of mitotic cytokinetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic cytokinetic process" EXACT [GOC:TermGenie] +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +is_a: GO:1903490 ! positive regulation of mitotic cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902410 ! mitotic cytokinetic process +relationship: positively_regulates GO:1902410 ! mitotic cytokinetic process +created_by: tb +creation_date: 2014-09-15T23:11:55Z + +[Term] +id: GO:1903439 +name: calcitonin family receptor complex +namespace: cellular_component +def: "A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:0097648 ! G protein-coupled receptor complex +created_by: pr +creation_date: 2014-09-16T13:25:11Z + +[Term] +id: GO:1903440 +name: amylin receptor complex +namespace: cellular_component +def: "A protein complex which is capable of amylin receptor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:10871296, PMID:12037140, PMID:18687416] +is_a: GO:1903439 ! calcitonin family receptor complex +created_by: pr +creation_date: 2014-09-16T13:25:20Z + +[Term] +id: GO:1903441 +name: protein localization to ciliary membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] +synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie] +is_a: GO:0061512 ! protein localization to cilium +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery +created_by: pr +creation_date: 2014-09-16T15:15:39Z + +[Term] +id: GO:1903442 +name: response to lipoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus." [GO_REF:0000071, GOC:sl, GOC:TermGenie, PMID:23232760] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0070542 ! response to fatty acid +created_by: jl +creation_date: 2014-09-17T13:52:03Z + +[Term] +id: GO:1903443 +name: cellular response to lipoic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus." [GO_REF:0000071, GOC:sl, GOC:TermGenie, PMID:23232760] +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1903442 ! response to lipoic acid +created_by: jl +creation_date: 2014-09-17T13:52:12Z + +[Term] +id: GO:1903444 +name: negative regulation of brown fat cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:23977283] +synonym: "down regulation of brown adipocyte cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of brown adipocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of brown fat cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of brown adipocyte cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of brown adipocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of brown fat cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of brown adipocyte cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of brown adipocyte differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of brown fat cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of brown adipocyte cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of brown adipocyte differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of brown fat cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of brown adipocyte cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of brown adipocyte differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045599 ! negative regulation of fat cell differentiation +is_a: GO:0090335 ! regulation of brown fat cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050873 ! brown fat cell differentiation +relationship: negatively_regulates GO:0050873 ! brown fat cell differentiation +created_by: hjd +creation_date: 2014-09-17T19:15:00Z + +[Term] +id: GO:1903445 +name: protein transport from ciliary membrane to plasma membrane +namespace: biological_process +def: "The directed movement of protein from ciliary membrane to plasma membrane." [GO_REF:0000078, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] +is_a: GO:0032594 ! protein transport within lipid bilayer +is_a: GO:0061951 ! establishment of protein localization to plasma membrane +created_by: pr +creation_date: 2014-09-18T07:46:10Z + +[Term] +id: GO:1903446 +name: geraniol metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving geraniol." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:23200656] +synonym: "geraniol metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016093 ! polyprenol metabolic process +is_a: GO:0016098 ! monoterpenoid metabolic process +is_a: GO:0034308 ! primary alcohol metabolic process +created_by: di +creation_date: 2014-09-19T08:18:34Z + +[Term] +id: GO:1903447 +name: geraniol catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of geraniol." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:23200656] +synonym: "geraniol breakdown" EXACT [GOC:TermGenie] +synonym: "geraniol catabolism" EXACT [GOC:TermGenie] +synonym: "geraniol degradation" EXACT [GOC:TermGenie] +is_a: GO:0016095 ! polyprenol catabolic process +is_a: GO:0016100 ! monoterpenoid catabolic process +is_a: GO:0034310 ! primary alcohol catabolic process +is_a: GO:1903446 ! geraniol metabolic process +created_by: di +creation_date: 2014-09-19T08:18:44Z + +[Term] +id: GO:1903448 +name: geraniol biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of geraniol." [GO_REF:0000068, GOC:di, GOC:TermGenie, PMID:23200656] +synonym: "geraniol anabolism" EXACT [GOC:TermGenie] +synonym: "geraniol biosynthesis" EXACT [GOC:TermGenie] +synonym: "geraniol formation" EXACT [GOC:TermGenie] +synonym: "geraniol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016094 ! polyprenol biosynthetic process +is_a: GO:0016099 ! monoterpenoid biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:1903446 ! geraniol metabolic process +created_by: di +creation_date: 2014-09-19T08:18:52Z + +[Term] +id: GO:1903449 +name: androst-4-ene-3,17-dione biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione." [GO_REF:0000068, GOC:mr, GOC:TermGenie, PMID:2028480, PMID:4149619] +synonym: "androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "androstenedione biosynthetic process" EXACT [] +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:0120178 ! steroid hormone biosynthetic process +created_by: mr +creation_date: 2014-09-19T20:18:19Z + +[Term] +id: GO:1903450 +name: regulation of G1 to G0 transition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G1 to G0 transition." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24088570] +synonym: "regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "regulation of stationary phase" RELATED [GOC:TermGenie] +is_a: GO:0010564 ! regulation of cell cycle process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070314 ! G1 to G0 transition +relationship: regulates GO:0070314 ! G1 to G0 transition +created_by: di +creation_date: 2014-09-19T22:23:13Z + +[Term] +id: GO:1903451 +name: negative regulation of G1 to G0 transition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24088570] +synonym: "down regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "down regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "down regulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "down regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "down regulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "down-regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "down-regulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "down-regulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "downregulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "downregulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "downregulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "downregulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "downregulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "inhibition of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "inhibition of establishment of cell quiescence" NARROW [GOC:TermGenie] +synonym: "inhibition of G1 to G0 transition" NARROW [GOC:TermGenie] +synonym: "inhibition of G1/G0 transition" NARROW [GOC:TermGenie] +synonym: "inhibition of stationary phase" RELATED [GOC:TermGenie] +synonym: "negative regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "negative regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "negative regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "negative regulation of stationary phase" RELATED [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:1903450 ! regulation of G1 to G0 transition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070314 ! G1 to G0 transition +relationship: negatively_regulates GO:0070314 ! G1 to G0 transition +created_by: di +creation_date: 2014-09-19T22:23:22Z + +[Term] +id: GO:1903452 +name: positive regulation of G1 to G0 transition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G1 to G0 transition." [GO_REF:0000058, GOC:di, GOC:TermGenie, PMID:24088570] +synonym: "activation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "activation of establishment of cell quiescence" NARROW [GOC:TermGenie] +synonym: "activation of G1 to G0 transition" NARROW [GOC:TermGenie] +synonym: "activation of G1/G0 transition" NARROW [GOC:TermGenie] +synonym: "activation of stationary phase" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "positive regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "positive regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "positive regulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "up regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "up regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "up regulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "up regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "up regulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "up-regulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "up-regulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "up-regulation of stationary phase" RELATED [GOC:TermGenie] +synonym: "upregulation of cell cycle quiescence" RELATED [GOC:TermGenie] +synonym: "upregulation of establishment of cell quiescence" EXACT [GOC:TermGenie] +synonym: "upregulation of G1 to G0 transition" EXACT [GOC:TermGenie] +synonym: "upregulation of G1/G0 transition" EXACT [GOC:TermGenie] +synonym: "upregulation of stationary phase" RELATED [GOC:TermGenie] +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1903450 ! regulation of G1 to G0 transition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070314 ! G1 to G0 transition +relationship: positively_regulates GO:0070314 ! G1 to G0 transition +created_by: di +creation_date: 2014-09-19T22:23:30Z + +[Term] +id: GO:1903453 +name: RNA interference involved in olfactory learning +namespace: biological_process +def: "Any RNA interference that is involved in olfactory learning." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:23993094] +synonym: "posttranscriptional gene silencing by siRNA involved in olfactory learning" EXACT [GOC:TermGenie] +synonym: "RNAi involved in olfactory learning" EXACT [GOC:TermGenie] +is_a: GO:0016246 ! RNA interference +intersection_of: GO:0016246 ! RNA interference +intersection_of: part_of GO:0008355 ! olfactory learning +relationship: part_of GO:0008355 ! olfactory learning +created_by: kmv +creation_date: 2014-09-22T13:50:09Z + +[Term] +id: GO:1903454 +name: regulation of androst-4-ene-3,17-dione biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:24399684] +synonym: "regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +relationship: regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +created_by: mr +creation_date: 2014-09-22T14:36:50Z + +[Term] +id: GO:1903455 +name: negative regulation of androst-4-ene-3,17-dione biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:24399684] +synonym: "down regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "down regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "downregulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of androst-4-ene-3,17-dione anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of androst-4-ene-3,17-dione biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of androst-4-ene-3,17-dione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of androst-4-ene-3,17-dione formation" NARROW [GOC:TermGenie] +synonym: "inhibition of androst-4-ene-3,17-dione synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of androstenedione" NARROW [GOC:TermGenie] +synonym: "negative regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1903454 ! regulation of androst-4-ene-3,17-dione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +relationship: negatively_regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +created_by: mr +creation_date: 2014-09-22T14:36:59Z + +[Term] +id: GO:1903456 +name: positive regulation of androst-4-ene-3,17-dione biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:24399684] +synonym: "activation of androst-4-ene-3,17-dione anabolism" NARROW [GOC:TermGenie] +synonym: "activation of androst-4-ene-3,17-dione biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of androst-4-ene-3,17-dione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of androst-4-ene-3,17-dione formation" NARROW [GOC:TermGenie] +synonym: "activation of androst-4-ene-3,17-dione synthesis" NARROW [GOC:TermGenie] +synonym: "activation of androstenedione" NARROW [GOC:TermGenie] +synonym: "positive regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "up regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of androst-4-ene-3,17-dione anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of androst-4-ene-3,17-dione biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of androst-4-ene-3,17-dione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of androst-4-ene-3,17-dione formation" EXACT [GOC:TermGenie] +synonym: "upregulation of androst-4-ene-3,17-dione synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of androstenedione biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1903454 ! regulation of androst-4-ene-3,17-dione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +relationship: positively_regulates GO:1903449 ! androst-4-ene-3,17-dione biosynthetic process +created_by: mr +creation_date: 2014-09-22T14:37:07Z + +[Term] +id: GO:1903457 +name: lactate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactate." [GO_REF:0000068, GOC:mengo_curators, GOC:TermGenie, PMID:8941775] +synonym: "lactate breakdown" EXACT [GOC:TermGenie] +synonym: "lactate catabolism" EXACT [GOC:TermGenie] +synonym: "lactate degradation" EXACT [GOC:TermGenie] +is_a: GO:0006089 ! lactate metabolic process +is_a: GO:0072329 ! monocarboxylic acid catabolic process +is_a: GO:1901616 ! organic hydroxy compound catabolic process +created_by: pr +creation_date: 2014-09-23T08:41:03Z + +[Term] +id: GO:1903459 +name: mitotic DNA replication lagging strand elongation +namespace: biological_process +def: "Any lagging strand elongation that is involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "lagging strand elongation involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "lagging strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "lagging strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "lagging strand elongation involved in mitotic DNA replication" EXACT [] +synonym: "lagging strand elongation involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "lagging strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0006273 ! lagging strand elongation +is_a: GO:1902983 ! DNA strand elongation involved in mitotic DNA replication +intersection_of: GO:0006273 ! lagging strand elongation +intersection_of: part_of GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:32:54Z + +[Term] +id: GO:1903460 +name: mitotic DNA replication leading strand elongation +namespace: biological_process +def: "Any leading strand elongation that is involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "leading strand elongation involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "leading strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "leading strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "leading strand elongation involved in mitotic DNA replication" EXACT [] +synonym: "leading strand elongation involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "leading strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0006272 ! leading strand elongation +is_a: GO:1902983 ! DNA strand elongation involved in mitotic DNA replication +intersection_of: GO:0006272 ! leading strand elongation +intersection_of: part_of GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:33:03Z + +[Term] +id: GO:1903461 +name: Okazaki fragment processing involved in mitotic DNA replication +namespace: biological_process +def: "Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "DNA replication, Okazaki fragment processing involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA replication, Okazaki fragment processing involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication, Okazaki fragment processing involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication, Okazaki fragment processing involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA replication, Okazaki fragment processing involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0033567 ! DNA replication, Okazaki fragment processing +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0033567 ! DNA replication, Okazaki fragment processing +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:33:11Z + +[Term] +id: GO:1903463 +name: regulation of mitotic cell cycle DNA replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0033262 ! regulation of nuclear cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902969 ! mitotic DNA replication +relationship: regulates GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:38:25Z + +[Term] +id: GO:1903464 +name: negative regulation of mitotic cell cycle DNA replication +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "down regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of DNA replication involved in S phase involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replication involved in S-phase involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic nuclear cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "negative regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "negative regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:1902576 ! negative regulation of nuclear cell cycle DNA replication +is_a: GO:1903463 ! regulation of mitotic cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902969 ! mitotic DNA replication +relationship: negatively_regulates GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:38:33Z + +[Term] +id: GO:1903465 +name: positive regulation of mitotic cell cycle DNA replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "activation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "activation of DNA replication involved in S phase involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of DNA replication involved in S-phase involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of mitotic cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "activation of mitotic nuclear cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "activation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "positive regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "positive regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0010571 ! positive regulation of nuclear cell cycle DNA replication +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:1903463 ! regulation of mitotic cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902969 ! mitotic DNA replication +relationship: positively_regulates GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:38:41Z + +[Term] +id: GO:1903466 +name: regulation of mitotic DNA replication initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +is_a: GO:0030174 ! regulation of DNA-dependent DNA replication initiation +is_a: GO:1903463 ! regulation of mitotic cell cycle DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902975 ! mitotic DNA replication initiation +relationship: regulates GO:1902975 ! mitotic DNA replication initiation +created_by: vw +creation_date: 2014-09-23T13:38:49Z + +[Term] +id: GO:1903467 +name: negative regulation of mitotic DNA replication initiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA replication initiation involved in mitotic DNA replication" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +is_a: GO:0032297 ! negative regulation of DNA-dependent DNA replication initiation +is_a: GO:1903464 ! negative regulation of mitotic cell cycle DNA replication +is_a: GO:1903466 ! regulation of mitotic DNA replication initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902975 ! mitotic DNA replication initiation +relationship: negatively_regulates GO:1902975 ! mitotic DNA replication initiation +created_by: vw +creation_date: 2014-09-23T13:38:58Z + +[Term] +id: GO:1903468 +name: positive regulation of DNA replication initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "activation of DNA replication initiation involved in mitotic cell cycle DNA replication" NARROW [GOC:TermGenie] +synonym: "activation of DNA replication initiation involved in mitotic DNA replication" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA replication initiation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +is_a: GO:0032298 ! positive regulation of DNA-dependent DNA replication initiation +is_a: GO:1903465 ! positive regulation of mitotic cell cycle DNA replication +is_a: GO:1903466 ! regulation of mitotic DNA replication initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902975 ! mitotic DNA replication initiation +relationship: positively_regulates GO:1902975 ! mitotic DNA replication initiation +created_by: vw +creation_date: 2014-09-23T13:39:06Z + +[Term] +id: GO:1903469 +name: removal of RNA primer involved in mitotic DNA replication +namespace: biological_process +def: "Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "DNA replication, removal of RNA primer involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA replication, removal of RNA primer involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication, removal of RNA primer involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA replication, removal of RNA primer involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA replication, removal of RNA primer involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "Okazaki initiator RNA removal involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0043137 ! DNA replication, removal of RNA primer +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0043137 ! DNA replication, removal of RNA primer +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: vw +creation_date: 2014-09-23T13:42:24Z + +[Term] +id: GO:1903470 +name: obsolete actomyosin contractile ring assembly involved in mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any actomyosin contractile ring assembly that is involved in mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "constriction ring assembly involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "contractile ring assembly involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "cytokinesis, actomyosin contractile ring assembly involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "cytokinesis, actomyosin contractile ring formation involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "cytokinesis, actomyosin ring biosynthesis involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "cytokinesis, actomyosin ring formation involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "cytokinesis, contractile ring assembly involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: vw +creation_date: 2014-09-23T14:06:50Z + +[Term] +id: GO:1903471 +name: regulation of mitotic actomyosin contractile ring contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0031991 ! regulation of actomyosin contractile ring contraction +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +relationship: regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +created_by: vw +creation_date: 2014-09-23T14:10:22Z + +[Term] +id: GO:1903472 +name: negative regulation of mitotic actomyosin contractile ring contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "down regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic actomyosin contractile ring contraction" NARROW [GOC:TermGenie] +synonym: "negative regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1903437 ! negative regulation of mitotic cytokinetic process +is_a: GO:1903471 ! regulation of mitotic actomyosin contractile ring contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +relationship: negatively_regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +created_by: vw +creation_date: 2014-09-23T14:10:38Z + +[Term] +id: GO:1903473 +name: positive regulation of mitotic actomyosin contractile ring contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie, PMID:1234] +synonym: "activation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of mitotic actomyosin contractile ring contraction" NARROW [GOC:TermGenie] +synonym: "positive regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic actomyosin contractile ring contraction" EXACT [GOC:TermGenie] +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +is_a: GO:1903471 ! regulation of mitotic actomyosin contractile ring contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +relationship: positively_regulates GO:1902404 ! mitotic actomyosin contractile ring contraction +created_by: vw +creation_date: 2014-09-23T14:10:46Z + +[Term] +id: GO:1903474 +name: obsolete anchoring of the mitotic actomyosin contractile ring to the plasma membrane +namespace: biological_process +def: "OBSOLETE. A process that maintains the mitotic actinomyosin contractile ring at the plasma membrane." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw, PMID:19139265, PMID:28784611] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: vw +creation_date: 2014-09-23T14:12:48Z + +[Term] +id: GO:1903475 +name: mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0000915 ! actomyosin contractile ring assembly +is_a: GO:1902407 ! assembly of actomyosin apparatus involved in mitotic cytokinesis +intersection_of: GO:0000915 ! actomyosin contractile ring assembly +intersection_of: part_of GO:0000281 ! mitotic cytokinesis +created_by: vw +creation_date: 2014-09-23T14:42:12Z + +[Term] +id: GO:1903476 +name: protein localization to cell division site involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "protein localisation to cell division site involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "protein localization to cell division site involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "protein localization to cell division site involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:1902575 ! protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0072741 ! protein localization to cell division site +intersection_of: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +relationship: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2014-09-23T14:52:37Z + +[Term] +id: GO:1903477 +name: mitotic contractile ring actin filament bundle assembly +namespace: biological_process +def: "Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw] +synonym: "actin filament bundle assembly involved in mitotic actomyosin contractile ring assembly" EXACT [] +is_a: GO:0071519 ! actomyosin contractile ring actin filament bundle assembly +is_a: GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0051017 ! actin filament bundle assembly +intersection_of: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2014-09-23T14:56:01Z + +[Term] +id: GO:1903478 +name: actin filament bundle convergence involved in mitotic contractile ring assembly +namespace: biological_process +def: "Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw] +synonym: "actin filament bundle convergence involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "actin filament bundle convergence involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "actin filament bundle convergence involved in cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "actin filament bundle convergence involved in mitotic actomyosin contractile ring assembly" EXACT [] +is_a: GO:0071520 ! actomyosin contractile ring assembly actin filament bundle convergence +is_a: GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0090426 ! actin filament bundle convergence +intersection_of: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2014-09-23T15:03:11Z + +[Term] +id: GO:1903479 +name: mitotic actomyosin contractile ring assembly actin filament organization +namespace: biological_process +def: "Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [] +is_a: GO:1903047 ! mitotic cell cycle process +is_a: GO:2000689 ! actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0007015 ! actin filament organization +intersection_of: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +relationship: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2014-09-23T15:03:19Z + +[Term] +id: GO:1903480 +name: regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +is_a: GO:1903117 ! regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly +is_a: GO:1903499 ! regulation of mitotic actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +relationship: regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +created_by: vw +creation_date: 2014-09-23T16:03:42Z + +[Term] +id: GO:1903481 +name: negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "down regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "inhibition of actin filament organisation involved in mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of actin filament organization involved in mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +is_a: GO:1903480 ! regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +is_a: GO:1903500 ! negative regulation of mitotic actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +relationship: negatively_regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +created_by: vw +creation_date: 2014-09-23T16:03:50Z + +[Term] +id: GO:1903482 +name: positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "activation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "activation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "activation of actin filament organization involved in mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +is_a: GO:1903480 ! regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly +is_a: GO:1903501 ! positive regulation of mitotic actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +relationship: positively_regulates GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +created_by: vw +creation_date: 2014-09-23T16:03:59Z + +[Term] +id: GO:1903483 +name: obsolete regulation of maintenance of mitotic actomyosin contractile ring localization +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: vw +creation_date: 2014-09-23T16:12:19Z + +[Term] +id: GO:1903484 +name: obsolete negative regulation of maintenance of mitotic actomyosin contractile ring localization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "down regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down regulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "inhibition of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of maintenance of mitotic actomyosin contractile ring localization" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "negative regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "negative regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: vw +creation_date: 2014-09-23T16:12:28Z + +[Term] +id: GO:1903485 +name: obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization." [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "activation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "activation of maintenance of mitotic actomyosin contractile ring localization" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +synonym: "upregulation of cytokinetic ring anchoring involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of maintenance of mitotic actomyosin contractile ring localization" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: vw +creation_date: 2014-09-23T16:12:37Z + +[Term] +id: GO:1903486 +name: establishment of mitotic actomyosin contractile ring localization +namespace: biological_process +def: "Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "establishment of actomyosin contractile ring localization involved in mitotic cell cycle" EXACT [] +is_a: GO:0032188 ! establishment of actomyosin contractile ring localization +is_a: GO:1902405 ! mitotic actomyosin contractile ring localization +intersection_of: GO:0032188 ! establishment of actomyosin contractile ring localization +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: vw +creation_date: 2014-09-23T16:17:09Z + +[Term] +id: GO:1903487 +name: regulation of lactation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lactation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19563620] +is_a: GO:0050878 ! regulation of body fluid levels +is_a: GO:0051046 ! regulation of secretion +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007595 ! lactation +relationship: regulates GO:0007595 ! lactation +created_by: mr +creation_date: 2014-09-24T14:44:13Z + +[Term] +id: GO:1903488 +name: negative regulation of lactation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lactation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19563620] +synonym: "down regulation of lactation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactation" EXACT [GOC:TermGenie] +synonym: "downregulation of lactation" EXACT [GOC:TermGenie] +synonym: "inhibition of lactation" NARROW [GOC:TermGenie] +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903487 ! regulation of lactation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007595 ! lactation +relationship: negatively_regulates GO:0007595 ! lactation +created_by: mr +creation_date: 2014-09-24T14:44:22Z + +[Term] +id: GO:1903489 +name: positive regulation of lactation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lactation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:19563620] +synonym: "activation of lactation" NARROW [GOC:TermGenie] +synonym: "up regulation of lactation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactation" EXACT [GOC:TermGenie] +synonym: "upregulation of lactation" EXACT [GOC:TermGenie] +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903487 ! regulation of lactation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007595 ! lactation +relationship: positively_regulates GO:0007595 ! lactation +created_by: mr +creation_date: 2014-09-24T14:44:30Z + +[Term] +id: GO:1903490 +name: positive regulation of mitotic cytokinesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis." [GO_REF:0000058, GOC:TermGenie, PMID:24920823] +synonym: "activation of cytokinesis after mitosis" NARROW [GOC:TermGenie] +synonym: "activation of mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic cytokinesis" EXACT [GOC:TermGenie] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:1902412 ! regulation of mitotic cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000281 ! mitotic cytokinesis +relationship: positively_regulates GO:0000281 ! mitotic cytokinesis +created_by: al +creation_date: 2014-09-25T09:00:35Z + +[Term] +id: GO:1903491 +name: response to simvastatin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug." [GO_REF:0000071, GOC:sl, GOC:TermGenie, PMID:23100282] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0036273 ! response to statin +created_by: hp +creation_date: 2014-09-25T10:58:06Z + +[Term] +id: GO:1903492 +name: response to acetylsalicylate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity." [GO_REF:0000071, GOC:TermGenie, PMID:23392654] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061476 ! response to anticoagulant +is_a: GO:0061478 ! response to platelet aggregation inhibitor +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hp +creation_date: 2014-09-25T10:58:23Z + +[Term] +id: GO:1903493 +name: response to clopidogrel +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease." [GO_REF:0000071, GOC:TermGenie, PMID:23392654] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061476 ! response to anticoagulant +is_a: GO:0061478 ! response to platelet aggregation inhibitor +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hp +creation_date: 2014-09-25T11:36:42Z + +[Term] +id: GO:1903494 +name: response to dehydroepiandrosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:3585228] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: mr +creation_date: 2014-09-25T17:01:18Z + +[Term] +id: GO:1903495 +name: cellular response to dehydroepiandrosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:3585228] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1903494 ! response to dehydroepiandrosterone +created_by: mr +creation_date: 2014-09-25T17:01:26Z + +[Term] +id: GO:1903496 +name: response to 11-deoxycorticosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:3585228] +is_a: GO:0051385 ! response to mineralocorticoid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: mr +creation_date: 2014-09-25T17:01:35Z + +[Term] +id: GO:1903497 +name: cellular response to 11-deoxycorticosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:3585228] +is_a: GO:0071389 ! cellular response to mineralocorticoid stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1903496 ! response to 11-deoxycorticosterone +created_by: mr +creation_date: 2014-09-25T17:01:43Z + +[Term] +id: GO:1903498 +name: bundle sheath cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell." [GO_REF:0000086, GOC:tb, GOC:TermGenie, PMID:24517883] +is_a: GO:0030154 ! cell differentiation +created_by: tb +creation_date: 2014-09-26T01:31:04Z + +[Term] +id: GO:1903499 +name: regulation of mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:al, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw, PMID:18256290] +synonym: "regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic cytokinesis, actomyosin contractile ring assembly" EXACT [] +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +is_a: GO:2000431 ! regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +relationship: regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: pr +creation_date: 2014-09-30T10:13:50Z + +[Term] +id: GO:1903500 +name: negative regulation of mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:al, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw, PMID:18256290] +synonym: "down regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "down regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "downregulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of actomyosin contractile ring assembly involved in cytokinesis after mitosis" NARROW [GOC:TermGenie] +synonym: "inhibition of contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "inhibition of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitotic cytokinesis, actomyosin contractile ring assembly" EXACT [] +is_a: GO:1903437 ! negative regulation of mitotic cytokinetic process +is_a: GO:1903499 ! regulation of mitotic actomyosin contractile ring assembly +is_a: GO:2000432 ! negative regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +relationship: negatively_regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: pr +creation_date: 2014-09-30T10:13:59Z + +[Term] +id: GO:1903501 +name: positive regulation of mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly." [GO_REF:0000058, GOC:al, GOC:mtg_cell_cycle, GOC:TermGenie, GOC:vw, PMID:18256290] +synonym: "activation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" NARROW [GOC:TermGenie] +synonym: "activation of contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "activation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" NARROW [GOC:TermGenie] +synonym: "activation of mitotic actomyosin contractile ring assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic cytokinesis, actomyosin contractile ring assembly" EXACT [] +synonym: "up regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic actomyosin contractile ring assembly" EXACT [GOC:TermGenie] +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +is_a: GO:1903499 ! regulation of mitotic actomyosin contractile ring assembly +is_a: GO:2000433 ! positive regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +relationship: positively_regulates GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: pr +creation_date: 2014-09-30T10:14:07Z + +[Term] +id: GO:1903502 +name: translation repressor complex +namespace: cellular_component +def: "A protein complex which is capable of translation repressor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:14723848] +comment: An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction). +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-09-30T12:44:27Z + +[Term] +id: GO:1903503 +name: ATPase inhibitor complex +namespace: cellular_component +def: "A protein complex which is capable of ATPase inhibitor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16170325] +comment: An example of this is Mago in drome (P49028) in PMID:16170325 (inferred from direct assay). +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-09-30T13:55:37Z + +[Term] +id: GO:1903504 +name: regulation of mitotic spindle checkpoint +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint." [GO_REF:0000058, GOC:TermGenie, PMID:23442800] +comment: Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent). +subset: gocheck_do_not_manually_annotate +synonym: "regulation of mitotic cell cycle spindle checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0090231 ! regulation of spindle checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071174 ! mitotic spindle checkpoint +relationship: regulates GO:0071174 ! mitotic spindle checkpoint +created_by: al +creation_date: 2014-10-01T13:52:57Z + +[Term] +id: GO:1903505 +name: regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle." [GO_REF:0000058, GOC:TermGenie, PMID:24165938] +is_a: GO:0071342 ! regulation of establishment of actomyosin contractile ring localization +is_a: GO:1902471 ! regulation of mitotic actomyosin contractile ring localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903486 ! establishment of mitotic actomyosin contractile ring localization +relationship: regulates GO:1903486 ! establishment of mitotic actomyosin contractile ring localization +created_by: al +creation_date: 2014-10-01T13:59:19Z + +[Term] +id: GO:1903506 +name: regulation of nucleic acid-templated transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:txnOH, GOC:vw] +is_a: GO:2001141 ! regulation of RNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097659 ! nucleic acid-templated transcription +relationship: regulates GO:0097659 ! nucleic acid-templated transcription +created_by: pr +creation_date: 2014-10-01T14:44:47Z + +[Term] +id: GO:1903507 +name: negative regulation of nucleic acid-templated transcription +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:txnOH, GOC:vw] +synonym: "down regulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +synonym: "down-regulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +synonym: "downregulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +synonym: "inhibition of nucleic acid-templated transcription" NARROW [GOC:TermGenie] +is_a: GO:1902679 ! negative regulation of RNA biosynthetic process +is_a: GO:1903506 ! regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097659 ! nucleic acid-templated transcription +relationship: negatively_regulates GO:0097659 ! nucleic acid-templated transcription +created_by: pr +creation_date: 2014-10-01T14:44:56Z + +[Term] +id: GO:1903508 +name: positive regulation of nucleic acid-templated transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:txnOH, GOC:vw] +synonym: "activation of nucleic acid-templated transcription" NARROW [GOC:TermGenie] +synonym: "up regulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +synonym: "up-regulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +synonym: "upregulation of nucleic acid-templated transcription" EXACT [GOC:TermGenie] +is_a: GO:1902680 ! positive regulation of RNA biosynthetic process +is_a: GO:1903506 ! regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097659 ! nucleic acid-templated transcription +relationship: positively_regulates GO:0097659 ! nucleic acid-templated transcription +created_by: pr +creation_date: 2014-10-01T14:45:04Z + +[Term] +id: GO:1903509 +name: liposaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving liposaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:9452964] +synonym: "liposaccharide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006629 ! lipid metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: dph +creation_date: 2014-10-01T21:52:52Z + +[Term] +id: GO:1903510 +name: mucopolysaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091] +synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0030203 ! glycosaminoglycan metabolic process +created_by: dph +creation_date: 2014-10-01T21:55:47Z + +[Term] +id: GO:1903511 +name: orotic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving orotic acid." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:10727948] +synonym: "orotic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0072527 ! pyrimidine-containing compound metabolic process +created_by: dph +creation_date: 2014-10-01T21:58:06Z + +[Term] +id: GO:1903512 +name: phytanic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phytanic acid." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:16799769] +synonym: "phytanic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:0097089 ! methyl-branched fatty acid metabolic process +created_by: dph +creation_date: 2014-10-01T22:00:29Z + +[Term] +id: GO:1903513 +name: endoplasmic reticulum to cytosol transport +namespace: biological_process +def: "The directed movement of substances from endoplasmic reticulum to cytosol." [GO_REF:0000076, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:16402920] +synonym: "ER to cytosol transport" EXACT [GOC:TermGenie] +is_a: GO:0046907 ! intracellular transport +created_by: rl +creation_date: 2014-10-02T11:24:34Z + +[Term] +id: GO:1903514 +name: release of sequestered calcium ion into cytosol by endoplasmic reticulum +namespace: biological_process +def: "The directed movement of calcium ion from endoplasmic reticulum to cytosol." [GO_REF:0000078, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:16402920] +synonym: "calcium ion transport from endoplasmic reticulum to cytosol" BROAD [] +is_a: GO:0051209 ! release of sequestered calcium ion into cytosol +created_by: rl +creation_date: 2014-10-02T11:30:34Z + +[Term] +id: GO:1903515 +name: calcium ion transport from cytosol to endoplasmic reticulum +namespace: biological_process +def: "The directed movement of calcium ion from cytosol to endoplasmic reticulum." [GO_REF:0000078, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:16402920] +is_a: GO:0046967 ! cytosol to endoplasmic reticulum transport +is_a: GO:0060401 ! cytosolic calcium ion transport +is_a: GO:0070588 ! calcium ion transmembrane transport +created_by: rl +creation_date: 2014-10-02T14:51:20Z + +[Term] +id: GO:1903516 +name: regulation of single strand break repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of single strand break repair." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17395247] +is_a: GO:0006282 ! regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000012 ! single strand break repair +relationship: regulates GO:0000012 ! single strand break repair +created_by: rl +creation_date: 2014-10-06T10:58:52Z + +[Term] +id: GO:1903517 +name: negative regulation of single strand break repair +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17395247] +synonym: "down regulation of single strand break repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of single strand break repair" EXACT [GOC:TermGenie] +synonym: "downregulation of single strand break repair" EXACT [GOC:TermGenie] +synonym: "inhibition of single strand break repair" NARROW [GOC:TermGenie] +is_a: GO:0045738 ! negative regulation of DNA repair +is_a: GO:1903516 ! regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000012 ! single strand break repair +relationship: negatively_regulates GO:0000012 ! single strand break repair +created_by: rl +creation_date: 2014-10-06T10:59:01Z + +[Term] +id: GO:1903518 +name: positive regulation of single strand break repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of single strand break repair." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17395247] +synonym: "activation of single strand break repair" NARROW [GOC:TermGenie] +synonym: "up regulation of single strand break repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of single strand break repair" EXACT [GOC:TermGenie] +synonym: "upregulation of single strand break repair" EXACT [GOC:TermGenie] +is_a: GO:0045739 ! positive regulation of DNA repair +is_a: GO:1903516 ! regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000012 ! single strand break repair +relationship: positively_regulates GO:0000012 ! single strand break repair +created_by: rl +creation_date: 2014-10-06T10:59:10Z + +[Term] +id: GO:1903519 +name: regulation of mammary gland involution +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mammary gland involution." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23164222] +is_a: GO:0034103 ! regulation of tissue remodeling +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060056 ! mammary gland involution +relationship: regulates GO:0060056 ! mammary gland involution +created_by: dph +creation_date: 2014-10-06T12:01:22Z + +[Term] +id: GO:1903520 +name: negative regulation of mammary gland involution +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23164222] +synonym: "down regulation of mammary gland involution" EXACT [GOC:TermGenie] +synonym: "down-regulation of mammary gland involution" EXACT [GOC:TermGenie] +synonym: "downregulation of mammary gland involution" EXACT [GOC:TermGenie] +synonym: "inhibition of mammary gland involution" NARROW [GOC:TermGenie] +is_a: GO:0034104 ! negative regulation of tissue remodeling +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1903519 ! regulation of mammary gland involution +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060056 ! mammary gland involution +relationship: negatively_regulates GO:0060056 ! mammary gland involution +created_by: dph +creation_date: 2014-10-06T12:01:30Z + +[Term] +id: GO:1903521 +name: positive regulation of mammary gland involution +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mammary gland involution." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23164222] +synonym: "activation of mammary gland involution" NARROW [GOC:TermGenie] +synonym: "up regulation of mammary gland involution" EXACT [GOC:TermGenie] +synonym: "up-regulation of mammary gland involution" EXACT [GOC:TermGenie] +synonym: "upregulation of mammary gland involution" EXACT [GOC:TermGenie] +is_a: GO:0034105 ! positive regulation of tissue remodeling +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1903519 ! regulation of mammary gland involution +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060056 ! mammary gland involution +relationship: positively_regulates GO:0060056 ! mammary gland involution +created_by: dph +creation_date: 2014-10-06T12:01:39Z + +[Term] +id: GO:1903522 +name: regulation of blood circulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] +synonym: "regulation of hemolymph circulation" RELATED [GOC:TermGenie] +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008015 ! blood circulation +relationship: regulates GO:0008015 ! blood circulation +created_by: mr +creation_date: 2014-10-06T18:38:56Z + +[Term] +id: GO:1903523 +name: negative regulation of blood circulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] +synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "down regulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "downregulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "inhibition of blood circulation" NARROW [GOC:TermGenie] +synonym: "inhibition of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "negative regulation of hemolymph circulation" RELATED [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008015 ! blood circulation +relationship: negatively_regulates GO:0008015 ! blood circulation +created_by: mr +creation_date: 2014-10-06T18:39:05Z + +[Term] +id: GO:1903524 +name: positive regulation of blood circulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] +synonym: "activation of blood circulation" NARROW [GOC:TermGenie] +synonym: "activation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "positive regulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "up regulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemolymph circulation" RELATED [GOC:TermGenie] +synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie] +synonym: "upregulation of hemolymph circulation" RELATED [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008015 ! blood circulation +relationship: positively_regulates GO:0008015 ! blood circulation +created_by: mr +creation_date: 2014-10-06T18:39:13Z + +[Term] +id: GO:1903525 +name: regulation of membrane tubulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane tubulation." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:18388313] +synonym: "regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "regulation of vesicle scission" RELATED [GOC:TermGenie] +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097320 ! plasma membrane tubulation +relationship: regulates GO:0097320 ! plasma membrane tubulation +created_by: pm +creation_date: 2014-10-07T12:52:36Z + +[Term] +id: GO:1903526 +name: negative regulation of membrane tubulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:18388313] +synonym: "down regulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "down regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "downregulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane tubulation" NARROW [GOC:TermGenie] +synonym: "inhibition of plasma membrane tubulation" NARROW [GOC:TermGenie] +synonym: "negative regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903525 ! regulation of membrane tubulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097320 ! plasma membrane tubulation +relationship: negatively_regulates GO:0097320 ! plasma membrane tubulation +created_by: pm +creation_date: 2014-10-07T12:52:45Z + +[Term] +id: GO:1903527 +name: positive regulation of membrane tubulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane tubulation." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:18388313] +synonym: "activation of membrane tubulation" NARROW [GOC:TermGenie] +synonym: "activation of plasma membrane tubulation" NARROW [GOC:TermGenie] +synonym: "positive regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "up regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane tubulation" EXACT [GOC:TermGenie] +synonym: "upregulation of plasma membrane tubulation" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903525 ! regulation of membrane tubulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097320 ! plasma membrane tubulation +relationship: positively_regulates GO:0097320 ! plasma membrane tubulation +created_by: pm +creation_date: 2014-10-07T12:52:53Z + +[Term] +id: GO:1903528 +name: regulation of dCDP biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dCDP biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:16317005] +synonym: "regulation of dCDP anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of dCDP biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of dCDP formation" EXACT [GOC:TermGenie] +synonym: "regulation of dCDP synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900397 ! regulation of pyrimidine nucleotide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006240 ! dCDP biosynthetic process +relationship: regulates GO:0006240 ! dCDP biosynthetic process +created_by: al +creation_date: 2014-10-07T15:01:18Z + +[Term] +id: GO:1903529 +name: negative regulation of dCDP biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:16317005] +synonym: "down regulation of dCDP anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of dCDP biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of dCDP biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of dCDP formation" EXACT [GOC:TermGenie] +synonym: "down regulation of dCDP synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dCDP anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of dCDP biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dCDP biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of dCDP formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of dCDP synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dCDP anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of dCDP biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of dCDP biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of dCDP formation" EXACT [GOC:TermGenie] +synonym: "downregulation of dCDP synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of dCDP anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of dCDP biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of dCDP biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of dCDP formation" NARROW [GOC:TermGenie] +synonym: "inhibition of dCDP synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of dCDP anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of dCDP biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of dCDP formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of dCDP synthesis" EXACT [GOC:TermGenie] +is_a: GO:1900398 ! negative regulation of pyrimidine nucleotide biosynthetic process +is_a: GO:1903528 ! regulation of dCDP biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006240 ! dCDP biosynthetic process +relationship: negatively_regulates GO:0006240 ! dCDP biosynthetic process +created_by: al +creation_date: 2014-10-07T15:01:27Z + +[Term] +id: GO:1903530 +name: regulation of secretion by cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] +synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051046 ! regulation of secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032940 ! secretion by cell +relationship: regulates GO:0032940 ! secretion by cell +created_by: pm +creation_date: 2014-10-08T13:24:59Z + +[Term] +id: GO:1903531 +name: negative regulation of secretion by cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] +synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of secretion by cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032940 ! secretion by cell +relationship: negatively_regulates GO:0032940 ! secretion by cell +created_by: pm +creation_date: 2014-10-08T13:25:08Z + +[Term] +id: GO:1903532 +name: positive regulation of secretion by cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] +synonym: "activation of cellular secretion" NARROW [GOC:TermGenie] +synonym: "activation of secretion by cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032940 ! secretion by cell +relationship: positively_regulates GO:0032940 ! secretion by cell +created_by: pm +creation_date: 2014-10-08T13:25:17Z + +[Term] +id: GO:1903533 +name: regulation of protein targeting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein targeting." [GO_REF:0000058, GOC:TermGenie] +synonym: "regulation of nascent polypeptide association" RELATED [GOC:TermGenie] +synonym: "regulation of protein sorting along secretory pathway" NARROW [GOC:TermGenie] +is_a: GO:0033157 ! regulation of intracellular protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006605 ! protein targeting +relationship: regulates GO:0006605 ! protein targeting +created_by: al +creation_date: 2014-10-08T14:49:03Z + +[Term] +id: GO:1903534 +name: regulation of lactose biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lactose biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:12018418] +synonym: "regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "regulation of lactose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005989 ! lactose biosynthetic process +relationship: regulates GO:0005989 ! lactose biosynthetic process +created_by: mr +creation_date: 2014-10-08T16:26:05Z + +[Term] +id: GO:1903535 +name: negative regulation of lactose biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:12018418] +synonym: "down regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "down regulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "downregulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of lactose anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of lactose biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of lactose biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of lactose formation" NARROW [GOC:TermGenie] +synonym: "inhibition of lactose synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of lactose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:1903534 ! regulation of lactose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005989 ! lactose biosynthetic process +relationship: negatively_regulates GO:0005989 ! lactose biosynthetic process +created_by: mr +creation_date: 2014-10-08T16:26:14Z + +[Term] +id: GO:1903536 +name: positive regulation of lactose biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:12018418] +synonym: "activation of lactose anabolism" NARROW [GOC:TermGenie] +synonym: "activation of lactose biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of lactose biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of lactose formation" NARROW [GOC:TermGenie] +synonym: "activation of lactose synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "up regulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lactose synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of lactose anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of lactose biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of lactose biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of lactose formation" EXACT [GOC:TermGenie] +synonym: "upregulation of lactose synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:1903534 ! regulation of lactose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005989 ! lactose biosynthetic process +relationship: positively_regulates GO:0005989 ! lactose biosynthetic process +created_by: mr +creation_date: 2014-10-08T16:26:29Z + +[Term] +id: GO:1903537 +name: meiotic cell cycle process involved in oocyte maturation +namespace: biological_process +def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395] +synonym: "meiosis involved in oocyte maturation" BROAD [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:1903046 ! meiotic cell cycle process +intersection_of: part_of GO:0001556 ! oocyte maturation +relationship: part_of GO:0001556 ! oocyte maturation +created_by: pr +creation_date: 2014-10-09T10:46:14Z + +[Term] +id: GO:1903538 +name: regulation of meiotic cell cycle process involved in oocyte maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395] +synonym: "regulation of meiosis involved in oocyte maturation" BROAD [GOC:TermGenie] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051445 ! regulation of meiotic cell cycle +is_a: GO:1900193 ! regulation of oocyte maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +relationship: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +created_by: pr +creation_date: 2014-10-09T10:52:38Z + +[Term] +id: GO:1903539 +name: protein localization to postsynaptic membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, pmid:9753322] +synonym: "protein localisation in postsynaptic membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to postsynaptic membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in postsynaptic membrane" EXACT [GOC:TermGenie] +is_a: GO:0062237 ! protein localization to postsynapse +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1990778 ! protein localization to cell periphery +created_by: kmv +creation_date: 2014-10-10T11:23:53Z + +[Term] +id: GO:1903540 +name: establishment of protein localization to postsynaptic membrane +namespace: biological_process +def: "The directed movement of a protein to a specific location in a postsynaptic membrane." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, pmid:9753322] +synonym: "establishment of protein localisation in postsynaptic membrane" EXACT [GOC:TermGenie] +synonym: "establishment of protein localisation to postsynaptic membrane" EXACT [GOC:TermGenie] +synonym: "establishment of protein localization in postsynaptic membrane" EXACT [GOC:TermGenie] +is_a: GO:0090150 ! establishment of protein localization to membrane +is_a: GO:1903539 ! protein localization to postsynaptic membrane +created_by: kmv +creation_date: 2014-10-10T11:24:03Z + +[Term] +id: GO:1903541 +name: regulation of exosomal secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie] +is_a: GO:0017157 ! regulation of exocytosis +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990182 ! exosomal secretion +relationship: regulates GO:1990182 ! exosomal secretion +created_by: pga +creation_date: 2014-10-14T11:38:52Z + +[Term] +id: GO:1903542 +name: negative regulation of exosomal secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "down regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "downregulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "inhibition of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of exosomal secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of exosomal secretory pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of secretion of exosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie] +is_a: GO:0045920 ! negative regulation of exocytosis +is_a: GO:1903541 ! regulation of exosomal secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990182 ! exosomal secretion +relationship: negatively_regulates GO:1990182 ! exosomal secretion +created_by: pga +creation_date: 2014-10-14T11:39:02Z + +[Term] +id: GO:1903543 +name: positive regulation of exosomal secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "activation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "activation of exosomal secretion" NARROW [GOC:TermGenie] +synonym: "activation of exosomal secretory pathway" NARROW [GOC:TermGenie] +synonym: "activation of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] +synonym: "activation of secretion of exosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "up regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie] +synonym: "upregulation of exosomal protein secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0045921 ! positive regulation of exocytosis +is_a: GO:1903541 ! regulation of exosomal secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990182 ! exosomal secretion +relationship: positively_regulates GO:1990182 ! exosomal secretion +created_by: pga +creation_date: 2014-10-14T11:39:10Z + +[Term] +id: GO:1903544 +name: response to butyrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9734870] +is_a: GO:0070542 ! response to fatty acid +created_by: mr +creation_date: 2014-10-17T13:57:25Z + +[Term] +id: GO:1903545 +name: cellular response to butyrate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9734870] +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:1903544 ! response to butyrate +created_by: mr +creation_date: 2014-10-17T13:57:35Z + +[Term] +id: GO:1903546 +name: protein localization to photoreceptor outer segment +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment." [GO_REF:0000087, GOC:TermGenie, PMID:11481257, PMID:21867699] +synonym: "protein localisation in photoreceptor outer segment" EXACT [GOC:TermGenie] +synonym: "protein localisation to photoreceptor outer segment" EXACT [GOC:TermGenie] +synonym: "protein localization in photoreceptor outer segment" EXACT [GOC:TermGenie] +is_a: GO:0097499 ! protein localization to non-motile cilium +created_by: krc +creation_date: 2014-10-17T21:14:11Z + +[Term] +id: GO:1903547 +name: regulation of growth hormone activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of growth hormone activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:3068266] +synonym: "regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070186 ! growth hormone activity +relationship: regulates GO:0070186 ! growth hormone activity +created_by: mr +creation_date: 2014-10-20T15:18:36Z + +[Term] +id: GO:1903548 +name: negative regulation of growth hormone activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:3068266] +synonym: "down regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "down regulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "down regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "down regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "downregulation of GH activity" EXACT [GOC:TermGenie] +synonym: "downregulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "downregulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "downregulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GH activity" NARROW [GOC:TermGenie] +synonym: "inhibition of growth hormone activity" NARROW [GOC:TermGenie] +synonym: "inhibition of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "inhibition of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1900121 ! negative regulation of receptor binding +is_a: GO:1903547 ! regulation of growth hormone activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070186 ! growth hormone activity +relationship: negatively_regulates GO:0070186 ! growth hormone activity +created_by: mr +creation_date: 2014-10-20T15:18:45Z + +[Term] +id: GO:1903549 +name: positive regulation of growth hormone activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of growth hormone activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:3068266] +synonym: "activation of GH activity" NARROW [GOC:TermGenie] +synonym: "activation of growth hormone activity" NARROW [GOC:TermGenie] +synonym: "activation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "activation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "up regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "up regulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "up regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of GH activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of placental growth hormone activity" NARROW [GOC:TermGenie] +synonym: "upregulation of GH activity" EXACT [GOC:TermGenie] +synonym: "upregulation of growth hormone activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] +synonym: "upregulation of placental growth hormone activity" NARROW [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:1903547 ! regulation of growth hormone activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070186 ! growth hormone activity +relationship: positively_regulates GO:0070186 ! growth hormone activity +created_by: mr +creation_date: 2014-10-20T15:18:53Z + +[Term] +id: GO:1903551 +name: regulation of extracellular exosome assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071971 ! extracellular exosome assembly +relationship: regulates GO:0071971 ! extracellular exosome assembly +created_by: pga +creation_date: 2014-10-20T15:37:25Z + +[Term] +id: GO:1903552 +name: negative regulation of extracellular exosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:1903551 ! regulation of extracellular exosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071971 ! extracellular exosome assembly +relationship: negatively_regulates GO:0071971 ! extracellular exosome assembly +created_by: pga +creation_date: 2014-10-20T15:37:33Z + +[Term] +id: GO:1903553 +name: positive regulation of extracellular exosome assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] +synonym: "activation of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of extracellular vesicular exosome assembly" RELATED [GOC:vesicles] +synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:1903551 ! regulation of extracellular exosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071971 ! extracellular exosome assembly +relationship: positively_regulates GO:0071971 ! extracellular exosome assembly +created_by: pga +creation_date: 2014-10-20T15:37:42Z + +[Term] +id: GO:1903554 +name: G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium +namespace: biological_process +def: "Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, pmid:25303524] +synonym: "G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in defence response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in defence response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in defense response to Gram-negative bacteria" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in defense response to Gram-negative bacterium" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in Gram-negative antibacterial peptide activity" RELATED [GOC:TermGenie] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: part_of GO:0050829 ! defense response to Gram-negative bacterium +relationship: part_of GO:0050829 ! defense response to Gram-negative bacterium +created_by: kmv +creation_date: 2014-10-20T17:51:13Z + +[Term] +id: GO:1903555 +name: regulation of tumor necrosis factor superfamily cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +is_a: GO:0001817 ! regulation of cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +relationship: regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +created_by: pga +creation_date: 2014-10-21T10:26:05Z + +[Term] +id: GO:1903556 +name: negative regulation of tumor necrosis factor superfamily cytokine production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "down regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "down regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "down regulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +synonym: "down-regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "down-regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "down-regulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +synonym: "downregulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "downregulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "downregulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +synonym: "inhibition of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "inhibition of TNFSF cytokine production" NARROW [GOC:TermGenie] +synonym: "inhibition of tumor necrosis factor superfamily cytokine production" NARROW [GOC:TermGenie] +synonym: "negative regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "negative regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +relationship: negatively_regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +created_by: pga +creation_date: 2014-10-21T10:26:14Z + +[Term] +id: GO:1903557 +name: positive regulation of tumor necrosis factor superfamily cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "activation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "activation of TNFSF cytokine production" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor superfamily cytokine production" NARROW [GOC:TermGenie] +synonym: "positive regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "positive regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "up regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "up regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +synonym: "up-regulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "up-regulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +synonym: "upregulation of TNF superfamily production" RELATED [GOC:TermGenie] +synonym: "upregulation of TNFSF cytokine production" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor superfamily cytokine production" EXACT [GOC:TermGenie] +is_a: GO:0001819 ! positive regulation of cytokine production +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +relationship: positively_regulates GO:0071706 ! tumor necrosis factor superfamily cytokine production +created_by: pga +creation_date: 2014-10-21T10:26:23Z + +[Term] +id: GO:1903558 +name: 3-cyano-L-alanine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving 3-cyano-L-alanine." [GO_REF:0000068, GOC:kmv, GOC:TermGenie, pmid:24100226, pmid:24843024] +synonym: "3-cyano-L-alanine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0033052 ! cyanoamino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: kmv +creation_date: 2014-10-21T17:13:00Z + +[Term] +id: GO:1903559 +name: 3-cyano-L-alanine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine." [GO_REF:0000068, GOC:kmv, GOC:TermGenie, pmid:24100226, pmid:24843024] +synonym: "3-cyano-L-alanine breakdown" EXACT [GOC:TermGenie] +synonym: "3-cyano-L-alanine catabolism" EXACT [GOC:TermGenie] +synonym: "3-cyano-L-alanine degradation" EXACT [GOC:TermGenie] +is_a: GO:0050899 ! nitrile catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +is_a: GO:1903558 ! 3-cyano-L-alanine metabolic process +created_by: kmv +creation_date: 2014-10-21T17:13:10Z + +[Term] +id: GO:1903560 +name: 3-cyano-L-alanine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine." [GO_REF:0000068, GOC:kmv, GOC:TermGenie, pmid:24100226, pmid:24843024] +synonym: "3-cyano-L-alanine anabolism" EXACT [GOC:TermGenie] +synonym: "3-cyano-L-alanine biosynthesis" EXACT [GOC:TermGenie] +synonym: "3-cyano-L-alanine formation" EXACT [GOC:TermGenie] +synonym: "3-cyano-L-alanine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0080028 ! nitrile biosynthetic process +is_a: GO:1901607 ! alpha-amino acid biosynthetic process +is_a: GO:1903558 ! 3-cyano-L-alanine metabolic process +created_by: kmv +creation_date: 2014-10-21T17:13:26Z + +[Term] +id: GO:1903561 +name: extracellular vesicle +namespace: cellular_component +def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] +synonym: "microparticle" RELATED [GOC:vesicles] +is_a: GO:0031982 ! vesicle +is_a: GO:0043230 ! extracellular organelle +intersection_of: GO:0031982 ! vesicle +intersection_of: part_of GO:0005576 ! extracellular region +created_by: jl +creation_date: 2014-10-22T14:26:11Z + +[Term] +id: GO:1903562 +name: microtubule bundle formation involved in mitotic spindle midzone assembly +namespace: biological_process +def: "Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:15647375] +synonym: "microtubule bundle formation involved in mitotic spindle midzone assembly" EXACT [GOC:TermGenie] +synonym: "microtubule bundle formation involved in mitotic spindle midzone formation" EXACT [GOC:TermGenie] +synonym: "microtubule bundle formation involved in spindle midzone assembly involved in mitosis" EXACT [GOC:dos] +synonym: "microtubule bundling involved in mitotic spindle midzone assembly" RELATED [GOC:TermGenie] +synonym: "microtubule bundling involved in mitotic spindle midzone formation" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in spindle midzone assembly involved in mitosis" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in spindle midzone biogenesis involved in mitosis" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in spindle midzone formation involved in mitosis" EXACT [GOC:TermGenie] +is_a: GO:0001578 ! microtubule bundle formation +is_a: GO:1902850 ! microtubule cytoskeleton organization involved in mitosis +intersection_of: GO:0001578 ! microtubule bundle formation +intersection_of: part_of GO:0051256 ! mitotic spindle midzone assembly +relationship: part_of GO:0051256 ! mitotic spindle midzone assembly +created_by: vw +creation_date: 2014-10-23T11:04:56Z + +[Term] +id: GO:1903563 +name: microtubule bundle formation involved in horsetail-astral microtubule organization +namespace: biological_process +def: "Any microtubule bundle formation that is involved in horsetail-astral microtubule organization." [GO_REF:0000060, GOC:TermGenie, PMID:15647375] +synonym: "microtubule bundle formation involved in horsetail-astral microtubule array organization" EXACT [GOC:TermGenie] +synonym: "microtubule bundle formation involved in horsetail-astral microtubule organisation" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in horsetail-astral microtubule array organization" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in horsetail-astral microtubule organisation" EXACT [GOC:TermGenie] +synonym: "microtubule bundling involved in horsetail-astral microtubule organization" EXACT [GOC:TermGenie] +is_a: GO:0001578 ! microtubule bundle formation +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0001578 ! microtubule bundle formation +intersection_of: part_of GO:0032118 ! horsetail-astral microtubule organization +relationship: part_of GO:0032118 ! horsetail-astral microtubule organization +created_by: vw +creation_date: 2014-10-23T11:06:35Z + +[Term] +id: GO:1903564 +name: regulation of protein localization to cilium +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061512 ! protein localization to cilium +relationship: regulates GO:0061512 ! protein localization to cilium +created_by: krc +creation_date: 2014-10-24T20:58:11Z + +[Term] +id: GO:1903565 +name: negative regulation of protein localization to cilium +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localization to cilium" NARROW [GOC:TermGenie] +is_a: GO:1903564 ! regulation of protein localization to cilium +is_a: GO:1903828 ! negative regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061512 ! protein localization to cilium +relationship: negatively_regulates GO:0061512 ! protein localization to cilium +created_by: krc +creation_date: 2014-10-24T20:58:20Z + +[Term] +id: GO:1903566 +name: positive regulation of protein localization to cilium +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +synonym: "activation of protein localization to cilium" NARROW [GOC:TermGenie] +synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie] +is_a: GO:1903564 ! regulation of protein localization to cilium +is_a: GO:1903829 ! positive regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061512 ! protein localization to cilium +relationship: positively_regulates GO:0061512 ! protein localization to cilium +created_by: krc +creation_date: 2014-10-24T20:58:28Z + +[Term] +id: GO:1903567 +name: regulation of protein localization to ciliary membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +is_a: GO:1903564 ! regulation of protein localization to cilium +is_a: GO:1904375 ! regulation of protein localization to cell periphery +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903441 ! protein localization to ciliary membrane +relationship: regulates GO:1903441 ! protein localization to ciliary membrane +created_by: krc +creation_date: 2014-10-24T21:32:51Z + +[Term] +id: GO:1903568 +name: negative regulation of protein localization to ciliary membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in ciliary membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to ciliary membrane" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +is_a: GO:1903565 ! negative regulation of protein localization to cilium +is_a: GO:1903567 ! regulation of protein localization to ciliary membrane +is_a: GO:1904376 ! negative regulation of protein localization to cell periphery +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903441 ! protein localization to ciliary membrane +relationship: negatively_regulates GO:1903441 ! protein localization to ciliary membrane +created_by: krc +creation_date: 2014-10-24T21:32:59Z + +[Term] +id: GO:1903569 +name: positive regulation of protein localization to ciliary membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] +synonym: "activation of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in ciliary membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to ciliary membrane" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] +is_a: GO:1903566 ! positive regulation of protein localization to cilium +is_a: GO:1903567 ! regulation of protein localization to ciliary membrane +is_a: GO:1904377 ! positive regulation of protein localization to cell periphery +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903441 ! protein localization to ciliary membrane +relationship: positively_regulates GO:1903441 ! protein localization to ciliary membrane +created_by: krc +creation_date: 2014-10-24T21:33:08Z + +[Term] +id: GO:1903570 +name: regulation of protein kinase D signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein kinase D signaling." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +synonym: "regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +is_a: GO:1902531 ! regulation of intracellular signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0089700 ! protein kinase D signaling +relationship: regulates GO:0089700 ! protein kinase D signaling +created_by: rl +creation_date: 2014-10-27T15:18:00Z + +[Term] +id: GO:1903571 +name: negative regulation of protein kinase D signaling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +synonym: "down regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "down regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "down regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "inhibition of PKD signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "inhibition of protein kinase D signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of protein kinase D signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "inhibition of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +is_a: GO:1903570 ! regulation of protein kinase D signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0089700 ! protein kinase D signaling +relationship: negatively_regulates GO:0089700 ! protein kinase D signaling +created_by: rl +creation_date: 2014-10-27T15:18:10Z + +[Term] +id: GO:1903572 +name: positive regulation of protein kinase D signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein kinase D signaling." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20497126] +synonym: "activation of PKD signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "activation of protein kinase D signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of protein kinase D signaling" NARROW [GOC:TermGenie] +synonym: "activation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "activation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "positive regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of PKD signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of PKD signaling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of protein kinase D signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of protein kinase D signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of protein kinase D signaling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of protein kinase D signalling cascade" RELATED [GOC:TermGenie] +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +is_a: GO:1903570 ! regulation of protein kinase D signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0089700 ! protein kinase D signaling +relationship: positively_regulates GO:0089700 ! protein kinase D signaling +created_by: rl +creation_date: 2014-10-27T15:18:18Z + +[Term] +id: GO:1903573 +name: negative regulation of response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11381086] +synonym: "down regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "down regulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down regulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "downregulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "inhibition of ER stress response" NARROW [GOC:TermGenie] +synonym: "inhibition of response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "inhibition of response to ER stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to ER stress" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034976 ! response to endoplasmic reticulum stress +relationship: negatively_regulates GO:0034976 ! response to endoplasmic reticulum stress +created_by: bf +creation_date: 2014-10-27T16:15:30Z + +[Term] +id: GO:1903574 +name: negative regulation of cellular response to amino acid starvation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11381086] +synonym: "down regulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to amino acid starvation" NARROW [GOC:TermGenie] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0032108 ! negative regulation of response to nutrient levels +is_a: GO:1903832 ! regulation of cellular response to amino acid starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034198 ! cellular response to amino acid starvation +relationship: negatively_regulates GO:0034198 ! cellular response to amino acid starvation +created_by: bf +creation_date: 2014-10-27T16:21:02Z + +[Term] +id: GO:1903575 +name: cornified envelope assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a cornified envelope." [GO_REF:0000079, GOC:pm, GOC:TermGenie, PMID:22226963, PMID:24794495] +comment: An example of this is syntaxin 4 in PMID:22226963. +synonym: "cornified envelope formation" EXACT [GOC:TermGenie] +is_a: GO:0007009 ! plasma membrane organization +is_a: GO:0071709 ! membrane assembly +relationship: has_part GO:0003810 ! protein-glutamine gamma-glutamyltransferase activity +created_by: pr +creation_date: 2014-10-28T10:22:49Z + +[Term] +id: GO:1903576 +name: response to L-arginine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:6394628] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +created_by: mr +creation_date: 2014-10-29T22:18:39Z + +[Term] +id: GO:1903577 +name: cellular response to L-arginine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:6394628] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1903576 ! response to L-arginine +created_by: mr +creation_date: 2014-10-29T22:18:54Z + +[Term] +id: GO:1903578 +name: regulation of ATP metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:20695849] +synonym: "regulation of ATP metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019222 ! regulation of metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046034 ! ATP metabolic process +relationship: regulates GO:0046034 ! ATP metabolic process +created_by: sl +creation_date: 2014-10-30T19:04:24Z + +[Term] +id: GO:1903579 +name: negative regulation of ATP metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:20695849] +synonym: "down regulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of ATP metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046034 ! ATP metabolic process +relationship: negatively_regulates GO:0046034 ! ATP metabolic process +created_by: sl +creation_date: 2014-10-30T19:04:33Z + +[Term] +id: GO:1903580 +name: positive regulation of ATP metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ATP metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:20695849] +synonym: "activation of ATP metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of ATP metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP metabolism" EXACT [GOC:TermGenie] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046034 ! ATP metabolic process +relationship: positively_regulates GO:0046034 ! ATP metabolic process +created_by: sl +creation_date: 2014-10-30T19:04:42Z + +[Term] +id: GO:1903581 +name: regulation of basophil degranulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of basophil degranulation." [GO_REF:0000058, GOC:TermGenie, PMID:10880837] +is_a: GO:0002694 ! regulation of leukocyte activation +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +is_a: GO:0043300 ! regulation of leukocyte degranulation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002561 ! basophil degranulation +relationship: regulates GO:0002561 ! basophil degranulation +created_by: sl +creation_date: 2014-10-31T17:37:24Z + +[Term] +id: GO:1903582 +name: negative regulation of basophil degranulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation." [GO_REF:0000058, GOC:TermGenie, PMID:10880837] +synonym: "down regulation of basophil degranulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of basophil degranulation" EXACT [GOC:TermGenie] +synonym: "downregulation of basophil degranulation" EXACT [GOC:TermGenie] +synonym: "inhibition of basophil degranulation" NARROW [GOC:TermGenie] +is_a: GO:0002695 ! negative regulation of leukocyte activation +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:0043301 ! negative regulation of leukocyte degranulation +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:1903581 ! regulation of basophil degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002561 ! basophil degranulation +relationship: negatively_regulates GO:0002561 ! basophil degranulation +created_by: sl +creation_date: 2014-10-31T17:37:33Z + +[Term] +id: GO:1903583 +name: positive regulation of basophil degranulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of basophil degranulation." [GO_REF:0000058, GOC:TermGenie, PMID:10880837] +synonym: "activation of basophil degranulation" NARROW [GOC:TermGenie] +synonym: "up regulation of basophil degranulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of basophil degranulation" EXACT [GOC:TermGenie] +synonym: "upregulation of basophil degranulation" EXACT [GOC:TermGenie] +is_a: GO:0002696 ! positive regulation of leukocyte activation +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:0043302 ! positive regulation of leukocyte degranulation +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:1903581 ! regulation of basophil degranulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002561 ! basophil degranulation +relationship: positively_regulates GO:0002561 ! basophil degranulation +created_by: sl +creation_date: 2014-10-31T17:37:42Z + +[Term] +id: GO:1903584 +name: regulation of histone deubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone deubiquitination." [GO_REF:0000058, GOC:TermGenie, PMID:24526689] +synonym: "regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0090085 ! regulation of protein deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016578 ! histone deubiquitination +relationship: regulates GO:0016578 ! histone deubiquitination +created_by: lb +creation_date: 2014-11-03T13:47:26Z + +[Term] +id: GO:1903585 +name: negative regulation of histone deubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination." [GO_REF:0000058, GOC:TermGenie, PMID:24526689] +synonym: "down regulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone deubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of histone deubiquitinylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone deubiquitylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0090086 ! negative regulation of protein deubiquitination +is_a: GO:1903584 ! regulation of histone deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016578 ! histone deubiquitination +relationship: negatively_regulates GO:0016578 ! histone deubiquitination +created_by: lb +creation_date: 2014-11-03T13:47:35Z + +[Term] +id: GO:1903586 +name: positive regulation of histone deubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone deubiquitination." [GO_REF:0000058, GOC:TermGenie, PMID:24526689] +synonym: "activation of histone deubiquitination" NARROW [GOC:TermGenie] +synonym: "activation of histone deubiquitinylation" NARROW [GOC:TermGenie] +synonym: "activation of histone deubiquitylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "up regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone deubiquitylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone deubiquitination" EXACT [GOC:TermGenie] +synonym: "upregulation of histone deubiquitinylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone deubiquitylation" EXACT [GOC:TermGenie] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:1903003 ! positive regulation of protein deubiquitination +is_a: GO:1903584 ! regulation of histone deubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016578 ! histone deubiquitination +relationship: positively_regulates GO:0016578 ! histone deubiquitination +created_by: lb +creation_date: 2014-11-03T13:47:44Z + +[Term] +id: GO:1903587 +name: regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23388056] +synonym: "regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +is_a: GO:0001936 ! regulation of endothelial cell proliferation +is_a: GO:1903670 ! regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +relationship: regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +created_by: pga +creation_date: 2014-11-04T11:39:31Z + +[Term] +id: GO:1903588 +name: negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23388056] +synonym: "down regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +is_a: GO:0001937 ! negative regulation of endothelial cell proliferation +is_a: GO:1903587 ! regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis +is_a: GO:1903671 ! negative regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +relationship: negatively_regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +created_by: pga +creation_date: 2014-11-04T11:39:39Z + +[Term] +id: GO:1903589 +name: positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:23388056] +synonym: "activation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "activation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis" EXACT [GOC:TermGenie] +is_a: GO:0001938 ! positive regulation of endothelial cell proliferation +is_a: GO:1903587 ! regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis +is_a: GO:1903672 ! positive regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +relationship: positively_regulates GO:0002043 ! blood vessel endothelial cell proliferation involved in sprouting angiogenesis +created_by: pga +creation_date: 2014-11-04T11:39:47Z + +[Term] +id: GO:1903590 +name: regulation of lysozyme activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lysozyme activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:23954697] +synonym: "regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003796 ! lysozyme activity +relationship: regulates GO:0003796 ! lysozyme activity +created_by: mr +creation_date: 2014-11-05T21:41:22Z + +[Term] +id: GO:1903591 +name: negative regulation of lysozyme activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:23954697] +synonym: "down regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "down regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "down regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "down regulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "down regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "down regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "down-regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "down-regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "down-regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "down-regulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "down-regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "downregulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of globulin G" RELATED [GOC:TermGenie] +synonym: "downregulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "downregulation of L-7001" RELATED [GOC:TermGenie] +synonym: "downregulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "downregulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "downregulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "inhibition of 1,4-N-acetylmuramidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of globulin G" RELATED [GOC:TermGenie] +synonym: "inhibition of globulin G1" RELATED [GOC:TermGenie] +synonym: "inhibition of L-7001" RELATED [GOC:TermGenie] +synonym: "inhibition of lysozyme activity" NARROW [GOC:TermGenie] +synonym: "inhibition of lysozyme g" RELATED [GOC:TermGenie] +synonym: "inhibition of mucopeptide glucohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of mucopeptide N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of muramidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of N,O-diacetylmuramidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of peptidoglycan N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "negative regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "negative regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "negative regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "negative regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "negative regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:1903590 ! regulation of lysozyme activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003796 ! lysozyme activity +relationship: negatively_regulates GO:0003796 ! lysozyme activity +created_by: mr +creation_date: 2014-11-05T21:41:30Z + +[Term] +id: GO:1903592 +name: positive regulation of lysozyme activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lysozyme activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:23954697] +synonym: "activation of 1,4-N-acetylmuramidase activity" NARROW [GOC:TermGenie] +synonym: "activation of globulin G" RELATED [GOC:TermGenie] +synonym: "activation of globulin G1" RELATED [GOC:TermGenie] +synonym: "activation of L-7001" RELATED [GOC:TermGenie] +synonym: "activation of lysozyme activity" NARROW [GOC:TermGenie] +synonym: "activation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "activation of mucopeptide glucohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of mucopeptide N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of muramidase activity" NARROW [GOC:TermGenie] +synonym: "activation of N,O-diacetylmuramidase activity" NARROW [GOC:TermGenie] +synonym: "activation of peptidoglycan N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "positive regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "positive regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "positive regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "positive regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "up regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "up regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "up regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "up regulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "up regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "up regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of globulin G" RELATED [GOC:TermGenie] +synonym: "up-regulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "up-regulation of L-7001" RELATED [GOC:TermGenie] +synonym: "up-regulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "up-regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PR1-lysozyme" RELATED [GOC:TermGenie] +synonym: "upregulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of globulin G" RELATED [GOC:TermGenie] +synonym: "upregulation of globulin G1" RELATED [GOC:TermGenie] +synonym: "upregulation of L-7001" RELATED [GOC:TermGenie] +synonym: "upregulation of lysozyme activity" EXACT [GOC:TermGenie] +synonym: "upregulation of lysozyme g" RELATED [GOC:TermGenie] +synonym: "upregulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of muramidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PR1-lysozyme" RELATED [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903590 ! regulation of lysozyme activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003796 ! lysozyme activity +relationship: positively_regulates GO:0003796 ! lysozyme activity +created_by: mr +creation_date: 2014-11-05T21:41:39Z + +[Term] +id: GO:1903593 +name: regulation of histamine secretion by mast cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histamine secretion by mast cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18253931] +is_a: GO:0043269 ! regulation of ion transport +is_a: GO:0043304 ! regulation of mast cell degranulation +is_a: GO:0046883 ! regulation of hormone secretion +is_a: GO:0050727 ! regulation of inflammatory response +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0051588 ! regulation of neurotransmitter transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002553 ! histamine secretion by mast cell +relationship: regulates GO:0002553 ! histamine secretion by mast cell +created_by: als +creation_date: 2014-11-06T13:19:09Z + +[Term] +id: GO:1903594 +name: negative regulation of histamine secretion by mast cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18253931] +synonym: "down regulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +synonym: "downregulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +synonym: "inhibition of histamine secretion by mast cell" NARROW [GOC:TermGenie] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0043305 ! negative regulation of mast cell degranulation +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0050728 ! negative regulation of inflammatory response +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0051589 ! negative regulation of neurotransmitter transport +is_a: GO:1903593 ! regulation of histamine secretion by mast cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002553 ! histamine secretion by mast cell +relationship: negatively_regulates GO:0002553 ! histamine secretion by mast cell +created_by: als +creation_date: 2014-11-06T13:19:18Z + +[Term] +id: GO:1903595 +name: positive regulation of histamine secretion by mast cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18253931] +synonym: "activation of histamine secretion by mast cell" NARROW [GOC:TermGenie] +synonym: "up regulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +synonym: "upregulation of histamine secretion by mast cell" EXACT [GOC:TermGenie] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0043306 ! positive regulation of mast cell degranulation +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0050729 ! positive regulation of inflammatory response +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0051590 ! positive regulation of neurotransmitter transport +is_a: GO:1903593 ! regulation of histamine secretion by mast cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002553 ! histamine secretion by mast cell +relationship: positively_regulates GO:0002553 ! histamine secretion by mast cell +created_by: als +creation_date: 2014-11-06T13:19:26Z + +[Term] +id: GO:1903596 +name: regulation of gap junction assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gap junction assembly." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:25017399] +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016264 ! gap junction assembly +relationship: regulates GO:0016264 ! gap junction assembly +created_by: rl +creation_date: 2014-11-07T18:51:36Z + +[Term] +id: GO:1903597 +name: negative regulation of gap junction assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:25017399] +synonym: "down regulation of gap junction assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of gap junction assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of gap junction assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of gap junction assembly" NARROW [GOC:TermGenie] +is_a: GO:1901889 ! negative regulation of cell junction assembly +is_a: GO:1903596 ! regulation of gap junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016264 ! gap junction assembly +relationship: negatively_regulates GO:0016264 ! gap junction assembly +created_by: rl +creation_date: 2014-11-07T18:51:45Z + +[Term] +id: GO:1903598 +name: positive regulation of gap junction assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gap junction assembly." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:25017399] +synonym: "activation of gap junction assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of gap junction assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of gap junction assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of gap junction assembly" EXACT [GOC:TermGenie] +is_a: GO:1901890 ! positive regulation of cell junction assembly +is_a: GO:1903596 ! regulation of gap junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016264 ! gap junction assembly +relationship: positively_regulates GO:0016264 ! gap junction assembly +created_by: rl +creation_date: 2014-11-07T18:51:53Z + +[Term] +id: GO:1903599 +name: positive regulation of autophagy of mitochondrion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy." [GO_REF:0000058, GOC:autophagy, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21753002] +comment: An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay +synonym: "activation of mitochondrion degradation" RELATED [GOC:TermGenie] +synonym: "activation of mitophagy" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial degradation" BROAD [GOC:TermGenie] +synonym: "up regulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "up regulation of mitophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "up-regulation of mitophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrion degradation" BROAD [GOC:TermGenie] +synonym: "upregulation of mitophagy" EXACT [GOC:TermGenie] +is_a: GO:0010508 ! positive regulation of autophagy +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:1903146 ! regulation of autophagy of mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000422 ! autophagy of mitochondrion +relationship: positively_regulates GO:0000422 ! autophagy of mitochondrion +created_by: pad +creation_date: 2014-11-10T14:25:53Z + +[Term] +id: GO:1903600 +name: glutaminase complex +namespace: cellular_component +def: "A protein complex which is capable of glutaminase activity." [GO_REF:0000088, GOC:TermGenie, PMID:14764090] +synonym: "Sno1p-Snz1p" EXACT [] +is_a: GO:1902494 ! catalytic complex +created_by: ew +creation_date: 2014-11-11T18:41:42Z + +[Term] +id: GO:1903601 +name: thermospermine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving thermospermine." [GO_REF:0000068, GOC:TermGenie, PMID:24906355] +synonym: "thermospermine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006595 ! polyamine metabolic process +created_by: tb +creation_date: 2014-11-12T18:47:55Z + +[Term] +id: GO:1903602 +name: thermospermine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of thermospermine." [GO_REF:0000068, GOC:TermGenie, PMID:24906355] +synonym: "thermospermine breakdown" EXACT [GOC:TermGenie] +synonym: "thermospermine catabolism" EXACT [GOC:TermGenie] +synonym: "thermospermine degradation" EXACT [GOC:TermGenie] +is_a: GO:0006598 ! polyamine catabolic process +is_a: GO:1903601 ! thermospermine metabolic process +created_by: tb +creation_date: 2014-11-12T18:48:04Z + +[Term] +id: GO:1903603 +name: thermospermine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of thermospermine." [GO_REF:0000068, GOC:TermGenie, PMID:24906355] +synonym: "thermospermine anabolism" EXACT [GOC:TermGenie] +synonym: "thermospermine biosynthesis" EXACT [GOC:TermGenie] +synonym: "thermospermine formation" EXACT [GOC:TermGenie] +synonym: "thermospermine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006596 ! polyamine biosynthetic process +is_a: GO:1903601 ! thermospermine metabolic process +created_by: tb +creation_date: 2014-11-12T18:48:12Z + +[Term] +id: GO:1903604 +name: cytochrome metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cytochrome." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:19721088] +synonym: "cytochrome metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019538 ! protein metabolic process +created_by: dph +creation_date: 2014-11-13T20:01:09Z + +[Term] +id: GO:1903605 +name: cytochrome biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a cytochrome." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:19721088] +synonym: "cytochrome anabolism" EXACT [GOC:TermGenie] +synonym: "cytochrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "cytochrome formation" EXACT [GOC:TermGenie] +synonym: "cytochrome synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009059 ! macromolecule biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +is_a: GO:1903604 ! cytochrome metabolic process +created_by: dph +creation_date: 2014-11-13T20:01:18Z + +[Term] +id: GO:1903606 +name: cytochrome c metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving cytochrome c." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:19721088] +synonym: "cytochrome c metabolism" EXACT [GOC:TermGenie] +is_a: GO:1903604 ! cytochrome metabolic process +created_by: dph +creation_date: 2014-11-13T20:01:27Z + +[Term] +id: GO:1903607 +name: cytochrome c biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of cytochrome c." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:19721088] +synonym: "cytochrome c anabolism" EXACT [GOC:TermGenie] +synonym: "cytochrome c biosynthesis" EXACT [GOC:TermGenie] +synonym: "cytochrome c formation" EXACT [GOC:TermGenie] +synonym: "cytochrome c synthesis" EXACT [GOC:TermGenie] +is_a: GO:1903605 ! cytochrome biosynthetic process +is_a: GO:1903606 ! cytochrome c metabolic process +created_by: dph +creation_date: 2014-11-13T20:01:35Z + +[Term] +id: GO:1903608 +name: protein localization to cytoplasmic stress granule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule." [GO_REF:0000087, GOC:TermGenie, PMID:24755092] +synonym: "protein localisation in cytoplasmic stress granule" EXACT [GOC:TermGenie] +synonym: "protein localisation to cytoplasmic stress granule" EXACT [GOC:TermGenie] +synonym: "protein localization in cytoplasmic stress granule" EXACT [GOC:TermGenie] +synonym: "protein localization to stress granule" BROAD [] +is_a: GO:0033365 ! protein localization to organelle +created_by: mah +creation_date: 2014-11-14T16:20:32Z + +[Term] +id: GO:1903609 +name: negative regulation of inward rectifier potassium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18923542] +synonym: "down regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Kir channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of inward rectifier potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Kir channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of Kir channel activity" EXACT [GOC:TermGenie] +is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity +is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005242 ! inward rectifier potassium channel activity +relationship: negatively_regulates GO:0005242 ! inward rectifier potassium channel activity +created_by: rl +creation_date: 2014-11-14T20:29:14Z + +[Term] +id: GO:1903610 +name: regulation of calcium-dependent ATPase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10861851] +is_a: GO:0043462 ! regulation of ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030899 ! calcium-dependent ATPase activity +relationship: regulates GO:0030899 ! calcium-dependent ATPase activity +created_by: sl +creation_date: 2014-11-18T00:42:49Z + +[Term] +id: GO:1903611 +name: negative regulation of calcium-dependent ATPase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10861851] +synonym: "down regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium-dependent ATPase activity" NARROW [GOC:TermGenie] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:1903610 ! regulation of calcium-dependent ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030899 ! calcium-dependent ATPase activity +relationship: negatively_regulates GO:0030899 ! calcium-dependent ATPase activity +created_by: sl +creation_date: 2014-11-18T00:42:57Z + +[Term] +id: GO:1903612 +name: positive regulation of calcium-dependent ATPase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10861851] +synonym: "activation of calcium-dependent ATPase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:1903610 ! regulation of calcium-dependent ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030899 ! calcium-dependent ATPase activity +relationship: positively_regulates GO:0030899 ! calcium-dependent ATPase activity +created_by: sl +creation_date: 2014-11-18T00:43:06Z + +[Term] +id: GO:1903613 +name: regulation of protein tyrosine phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11129957] +synonym: "regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0043666 ! regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004725 ! protein tyrosine phosphatase activity +relationship: regulates GO:0004725 ! protein tyrosine phosphatase activity +created_by: sl +creation_date: 2014-11-18T01:11:38Z + +[Term] +id: GO:1903614 +name: negative regulation of protein tyrosine phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11129957] +synonym: "down regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of [phosphotyrosine]protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphoprotein phosphatase (phosphotyrosine) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphotyrosine histone phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphotyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphotyrosine protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphotyrosylprotein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PPT-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of protein phosphotyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of protein tyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of protein-tyrosine-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of protein-tyrosine-phosphate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PTP-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PTPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosine O-phosphate phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of tyrosylprotein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0032515 ! negative regulation of phosphoprotein phosphatase activity +is_a: GO:1903613 ! regulation of protein tyrosine phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004725 ! protein tyrosine phosphatase activity +relationship: negatively_regulates GO:0004725 ! protein tyrosine phosphatase activity +created_by: sl +creation_date: 2014-11-18T01:11:46Z + +[Term] +id: GO:1903615 +name: positive regulation of protein tyrosine phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11129957] +synonym: "activation of [phosphotyrosine]protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphoprotein phosphatase (phosphotyrosine) activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphotyrosine histone phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphotyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphotyrosine protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphotyrosylprotein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of PPT-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of protein phosphotyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of protein tyrosine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of protein-tyrosine-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of protein-tyrosine-phosphate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of PTP-phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of PTPase activity" NARROW [GOC:TermGenie] +synonym: "activation of tyrosine O-phosphate phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of tyrosylprotein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of [phosphotyrosine]protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphotyrosine histone phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphotyrosine protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphotyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PPT-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of protein phosphotyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of protein tyrosine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of protein-tyrosine-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of protein-tyrosine-phosphate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PTP-phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PTPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tyrosine O-phosphate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of tyrosylprotein phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0032516 ! positive regulation of phosphoprotein phosphatase activity +is_a: GO:1903613 ! regulation of protein tyrosine phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004725 ! protein tyrosine phosphatase activity +relationship: positively_regulates GO:0004725 ! protein tyrosine phosphatase activity +created_by: sl +creation_date: 2014-11-18T01:11:55Z + +[Term] +id: GO:1903616 +name: MAPK cascade involved in axon regeneration +namespace: biological_process +def: "Any MAPK cascade that is involved in axon regeneration." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:19164707, PMID:19417215, PMID:19737525] +synonym: "ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0000165 ! MAPK cascade +intersection_of: GO:0000165 ! MAPK cascade +intersection_of: part_of GO:0031103 ! axon regeneration +relationship: part_of GO:0031103 ! axon regeneration +created_by: kmv +creation_date: 2014-11-18T19:11:59Z + +[Term] +id: GO:1903617 +name: positive regulation of mitotic cytokinesis, site selection +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection." [GO_REF:0000058, GOC:TermGenie, PMID:21246752] +is_a: GO:1902472 ! regulation of mitotic cytokinesis, site selection +is_a: GO:1903438 ! positive regulation of mitotic cytokinetic process +is_a: GO:2000076 ! positive regulation cytokinesis, site selection +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902408 ! mitotic cytokinesis, site selection +relationship: positively_regulates GO:1902408 ! mitotic cytokinesis, site selection +created_by: vw +creation_date: 2014-11-19T10:52:25Z + +[Term] +id: GO:1903618 +name: regulation of transdifferentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transdifferentiation." [GO_REF:0000058, GOC:TermGenie, PMID:22118091] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060290 ! transdifferentiation +relationship: regulates GO:0060290 ! transdifferentiation +created_by: jl +creation_date: 2014-11-19T11:24:57Z + +[Term] +id: GO:1903619 +name: negative regulation of transdifferentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation." [GO_REF:0000058, GOC:TermGenie, PMID:22118091] +synonym: "down regulation of transdifferentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of transdifferentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of transdifferentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of transdifferentiation" NARROW [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1903618 ! regulation of transdifferentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060290 ! transdifferentiation +relationship: negatively_regulates GO:0060290 ! transdifferentiation +created_by: jl +creation_date: 2014-11-19T11:25:05Z + +[Term] +id: GO:1903620 +name: positive regulation of transdifferentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transdifferentiation." [GO_REF:0000058, GOC:TermGenie, PMID:22118091] +synonym: "activation of transdifferentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of transdifferentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of transdifferentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of transdifferentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1903618 ! regulation of transdifferentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060290 ! transdifferentiation +relationship: positively_regulates GO:0060290 ! transdifferentiation +created_by: jl +creation_date: 2014-11-19T11:25:14Z + +[Term] +id: GO:1903621 +name: protein localization to photoreceptor connecting cilium +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium." [GO_REF:0000087, GOC:lb, GOC:TermGenie, PMID:25398945] +synonym: "protein localisation in photoreceptor connecting cilium" EXACT [GOC:TermGenie] +synonym: "protein localisation to photoreceptor connecting cilium" EXACT [GOC:TermGenie] +synonym: "protein localization in photoreceptor connecting cilium" EXACT [GOC:TermGenie] +is_a: GO:0097499 ! protein localization to non-motile cilium +is_a: GO:1904491 ! protein localization to ciliary transition zone +created_by: jl +creation_date: 2014-11-19T17:17:17Z + +[Term] +id: GO:1903622 +name: regulation of RNA polymerase III activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA polymerase III activity." [GO_REF:0000059, GOC:TermGenie, PMID:25392932] +synonym: "regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +is_a: GO:0006359 ! regulation of transcription by RNA polymerase III +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001056 ! RNA polymerase III activity +relationship: regulates GO:0001056 ! RNA polymerase III activity +created_by: al +creation_date: 2014-11-19T18:24:29Z + +[Term] +id: GO:1903623 +name: negative regulation of RNA polymerase III activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity." [GO_REF:0000059, GOC:TermGenie, PMID:25392932] +synonym: "down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA polymerase III activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA polymerase III activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA polymerase III activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA polymerase III activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] +is_a: GO:0016480 ! negative regulation of transcription by RNA polymerase III +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1903622 ! regulation of RNA polymerase III activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001056 ! RNA polymerase III activity +relationship: negatively_regulates GO:0001056 ! RNA polymerase III activity +created_by: al +creation_date: 2014-11-19T18:24:37Z + +[Term] +id: GO:1903624 +name: regulation of DNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] +synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0051052 ! regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006308 ! DNA catabolic process +relationship: regulates GO:0006308 ! DNA catabolic process +created_by: sl +creation_date: 2014-11-19T22:36:35Z + +[Term] +id: GO:1903625 +name: negative regulation of DNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] +synonym: "down regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:1903624 ! regulation of DNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006308 ! DNA catabolic process +relationship: negatively_regulates GO:0006308 ! DNA catabolic process +created_by: sl +creation_date: 2014-11-19T22:36:43Z + +[Term] +id: GO:1903626 +name: positive regulation of DNA catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] +synonym: "activation of DNA breakdown" NARROW [GOC:TermGenie] +synonym: "activation of DNA catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of DNA catabolism" NARROW [GOC:TermGenie] +synonym: "activation of DNA degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:1903624 ! regulation of DNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006308 ! DNA catabolic process +relationship: positively_regulates GO:0006308 ! DNA catabolic process +created_by: sl +creation_date: 2014-11-19T22:36:51Z + +[Term] +id: GO:1903627 +name: regulation of dUTP diphosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1315924] +synonym: "regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of dUTPase activity" EXACT [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004170 ! dUTP diphosphatase activity +relationship: regulates GO:0004170 ! dUTP diphosphatase activity +created_by: sl +creation_date: 2014-11-20T00:00:36Z + +[Term] +id: GO:1903628 +name: negative regulation of dUTP diphosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1315924] +synonym: "down regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of deoxyuridine-triphosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of desoxyuridine 5'-triphosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of dUTP diphosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of dUTP nucleotidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of dUTP pyrophosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of dUTPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of dUTPase activity" EXACT [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:1903627 ! regulation of dUTP diphosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004170 ! dUTP diphosphatase activity +relationship: negatively_regulates GO:0004170 ! dUTP diphosphatase activity +created_by: sl +creation_date: 2014-11-20T00:00:44Z + +[Term] +id: GO:1903629 +name: positive regulation of dUTP diphosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1315924] +synonym: "activation of deoxyuridine-triphosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of desoxyuridine 5'-triphosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of dUTP diphosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of dUTP nucleotidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of dUTP pyrophosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of dUTPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of dUTPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyuridine-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of desoxyuridine 5'-triphosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of dUTP diphosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of dUTP nucleotidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of dUTP pyrophosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of dUTPase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1903627 ! regulation of dUTP diphosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004170 ! dUTP diphosphatase activity +relationship: positively_regulates GO:0004170 ! dUTP diphosphatase activity +created_by: sl +creation_date: 2014-11-20T00:00:56Z + +[Term] +id: GO:1903630 +name: regulation of aminoacyl-tRNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004812 ! aminoacyl-tRNA ligase activity +relationship: regulates GO:0004812 ! aminoacyl-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:22:04Z + +[Term] +id: GO:1903631 +name: negative regulation of aminoacyl-tRNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "down regulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "downregulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "inhibition of aminoacyl-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of aminoacyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +is_a: GO:0051352 ! negative regulation of ligase activity +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004812 ! aminoacyl-tRNA ligase activity +relationship: negatively_regulates GO:0004812 ! aminoacyl-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:22:12Z + +[Term] +id: GO:1903632 +name: positive regulation of aminoacyl-tRNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "activation of aminoacyl-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of aminoacyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "up regulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +synonym: "upregulation of aminoacyl-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aminoacyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aminoacyl-tRNA synthetase auxiliary protein activity" RELATED [GOC:TermGenie] +is_a: GO:0051351 ! positive regulation of ligase activity +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004812 ! aminoacyl-tRNA ligase activity +relationship: positively_regulates GO:0004812 ! aminoacyl-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:22:20Z + +[Term] +id: GO:1903633 +name: regulation of leucine-tRNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004823 ! leucine-tRNA ligase activity +relationship: regulates GO:0004823 ! leucine-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:24:48Z + +[Term] +id: GO:1903634 +name: negative regulation of leucine-tRNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "down regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of L-leucine:tRNALeu ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of leucine translase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucine-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of leucyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:1903631 ! negative regulation of aminoacyl-tRNA ligase activity +is_a: GO:1903633 ! regulation of leucine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004823 ! leucine-tRNA ligase activity +relationship: negatively_regulates GO:0004823 ! leucine-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:24:56Z + +[Term] +id: GO:1903635 +name: positive regulation of leucine-tRNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:2280766] +synonym: "activation of L-leucine:tRNALeu ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "activation of leucine translase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucine-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of leucyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-leucine:tRNALeu ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of leucine translase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of leucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:1903632 ! positive regulation of aminoacyl-tRNA ligase activity +is_a: GO:1903633 ! regulation of leucine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004823 ! leucine-tRNA ligase activity +relationship: positively_regulates GO:0004823 ! leucine-tRNA ligase activity +created_by: sl +creation_date: 2014-11-20T00:25:08Z + +[Term] +id: GO:1903636 +name: regulation of protein insertion into mitochondrial outer membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane." [GO_REF:0000058, GOC:TermGenie, PMID:16374546] +synonym: "regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "regulation of protein import into mitochondrial outer membrane" EXACT [] +synonym: "regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +is_a: GO:1903214 ! regulation of protein targeting to mitochondrion +is_a: GO:1904589 ! regulation of protein import +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +relationship: regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +created_by: pga +creation_date: 2014-11-20T15:54:44Z + +[Term] +id: GO:1903637 +name: negative regulation of protein insertion into mitochondrial outer membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane." [GO_REF:0000058, GOC:TermGenie, PMID:16374546] +synonym: "down regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "down regulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "downregulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial outer membrane protein import" NARROW [GOC:TermGenie] +synonym: "inhibition of protein import into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein insertion into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein transport into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein import into mitochondrial outer membrane" EXACT [] +synonym: "negative regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +is_a: GO:1903215 ! negative regulation of protein targeting to mitochondrion +is_a: GO:1903636 ! regulation of protein insertion into mitochondrial outer membrane +is_a: GO:1904590 ! negative regulation of protein import +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +relationship: negatively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +created_by: pga +creation_date: 2014-11-20T15:54:53Z + +[Term] +id: GO:1903638 +name: positive regulation of protein insertion into mitochondrial outer membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane." [GO_REF:0000058, GOC:TermGenie, PMID:16374546] +synonym: "activation of mitochondrial outer membrane protein import" NARROW [GOC:TermGenie] +synonym: "activation of protein import into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein insertion into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein transport into mitochondrial outer membrane" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein import into mitochondrial outer membrane" EXACT [] +synonym: "positive regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "up regulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial outer membrane protein import" EXACT [GOC:TermGenie] +synonym: "upregulation of protein import into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein insertion into mitochondrial outer membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein transport into mitochondrial outer membrane" EXACT [GOC:TermGenie] +is_a: GO:1903636 ! regulation of protein insertion into mitochondrial outer membrane +is_a: GO:1903955 ! positive regulation of protein targeting to mitochondrion +is_a: GO:1904591 ! positive regulation of protein import +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +relationship: positively_regulates GO:0045040 ! protein insertion into mitochondrial outer membrane +created_by: pga +creation_date: 2014-11-20T15:55:01Z + +[Term] +id: GO:1903639 +name: regulation of gastrin-induced gastric acid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11123201] +is_a: GO:0060453 ! regulation of gastric acid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001698 ! gastrin-induced gastric acid secretion +relationship: regulates GO:0001698 ! gastrin-induced gastric acid secretion +created_by: sl +creation_date: 2014-11-20T20:54:20Z + +[Term] +id: GO:1903640 +name: negative regulation of gastrin-induced gastric acid secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11123201] +synonym: "down regulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of gastrin-induced gastric acid secretion" NARROW [GOC:TermGenie] +is_a: GO:0060455 ! negative regulation of gastric acid secretion +is_a: GO:1903639 ! regulation of gastrin-induced gastric acid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001698 ! gastrin-induced gastric acid secretion +relationship: negatively_regulates GO:0001698 ! gastrin-induced gastric acid secretion +created_by: sl +creation_date: 2014-11-20T20:54:28Z + +[Term] +id: GO:1903641 +name: positive regulation of gastrin-induced gastric acid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11123201] +synonym: "activation of gastrin-induced gastric acid secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of gastrin-induced gastric acid secretion" EXACT [GOC:TermGenie] +is_a: GO:0060454 ! positive regulation of gastric acid secretion +is_a: GO:1903639 ! regulation of gastrin-induced gastric acid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001698 ! gastrin-induced gastric acid secretion +relationship: positively_regulates GO:0001698 ! gastrin-induced gastric acid secretion +created_by: sl +creation_date: 2014-11-20T20:54:37Z + +[Term] +id: GO:1903642 +name: regulation of recombination hotspot binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of recombination hotspot binding." [GO_REF:0000059, GOC:TermGenie, PMID:19436749] +synonym: "regulation of DNA binding, recombination hotspot" EXACT [GOC:TermGenie] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010844 ! recombination hotspot binding +relationship: regulates GO:0010844 ! recombination hotspot binding +created_by: al +creation_date: 2014-11-21T12:02:22Z + +[Term] +id: GO:1903643 +name: positive regulation of recombination hotspot binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of recombination hotspot binding." [GO_REF:0000059, GOC:TermGenie, PMID:19436749] +synonym: "activation of DNA binding, recombination hotspot" NARROW [GOC:TermGenie] +synonym: "activation of recombination hotspot binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA binding, recombination hotspot" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA binding, recombination hotspot" EXACT [GOC:TermGenie] +synonym: "up regulation of recombination hotspot binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA binding, recombination hotspot" EXACT [GOC:TermGenie] +synonym: "up-regulation of recombination hotspot binding" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA binding, recombination hotspot" EXACT [GOC:TermGenie] +synonym: "upregulation of recombination hotspot binding" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:1903642 ! regulation of recombination hotspot binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010844 ! recombination hotspot binding +relationship: positively_regulates GO:0010844 ! recombination hotspot binding +created_by: al +creation_date: 2014-11-21T12:02:31Z + +[Term] +id: GO:1903644 +name: regulation of chaperone-mediated protein folding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding." [GO_REF:0000058, GOC:TermGenie, PMID:24375412] +is_a: GO:1903332 ! regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061077 ! chaperone-mediated protein folding +relationship: regulates GO:0061077 ! chaperone-mediated protein folding +created_by: pga +creation_date: 2014-11-21T15:25:27Z + +[Term] +id: GO:1903645 +name: negative regulation of chaperone-mediated protein folding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding." [GO_REF:0000058, GOC:TermGenie, PMID:24375412] +synonym: "down regulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +synonym: "down-regulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +synonym: "downregulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +synonym: "inhibition of chaperone-mediated protein folding" NARROW [GOC:TermGenie] +is_a: GO:1903333 ! negative regulation of protein folding +is_a: GO:1903644 ! regulation of chaperone-mediated protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061077 ! chaperone-mediated protein folding +relationship: negatively_regulates GO:0061077 ! chaperone-mediated protein folding +created_by: pga +creation_date: 2014-11-21T15:25:35Z + +[Term] +id: GO:1903646 +name: positive regulation of chaperone-mediated protein folding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding." [GO_REF:0000058, GOC:TermGenie, PMID:24375412] +synonym: "activation of chaperone-mediated protein folding" NARROW [GOC:TermGenie] +synonym: "up regulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +synonym: "up-regulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +synonym: "upregulation of chaperone-mediated protein folding" EXACT [GOC:TermGenie] +is_a: GO:1903334 ! positive regulation of protein folding +is_a: GO:1903644 ! regulation of chaperone-mediated protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061077 ! chaperone-mediated protein folding +relationship: positively_regulates GO:0061077 ! chaperone-mediated protein folding +created_by: pga +creation_date: 2014-11-21T15:25:44Z + +[Term] +id: GO:1903647 +name: negative regulation of chlorophyll catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:24719469] +synonym: "down regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of chlorophyll breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of chlorophyll degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +is_a: GO:0010271 ! regulation of chlorophyll catabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1901405 ! negative regulation of tetrapyrrole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015996 ! chlorophyll catabolic process +relationship: negatively_regulates GO:0015996 ! chlorophyll catabolic process +created_by: tb +creation_date: 2014-11-22T00:18:25Z + +[Term] +id: GO:1903648 +name: positive regulation of chlorophyll catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:24719469] +synonym: "activation of chlorophyll breakdown" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll catabolism" NARROW [GOC:TermGenie] +synonym: "activation of chlorophyll degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of chlorophyll degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of chlorophyll degradation" EXACT [GOC:TermGenie] +is_a: GO:0010271 ! regulation of chlorophyll catabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1901406 ! positive regulation of tetrapyrrole catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015996 ! chlorophyll catabolic process +relationship: positively_regulates GO:0015996 ! chlorophyll catabolic process +created_by: tb +creation_date: 2014-11-22T00:18:34Z + +[Term] +id: GO:1903649 +name: regulation of cytoplasmic transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +is_a: GO:0032386 ! regulation of intracellular transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016482 ! cytosolic transport +relationship: regulates GO:0016482 ! cytosolic transport +created_by: jl +creation_date: 2014-11-24T13:38:17Z + +[Term] +id: GO:1903650 +name: negative regulation of cytoplasmic transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "down regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "down regulation of cytoplasmic transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic transport" EXACT [GOC:TermGenie] +synonym: "downregulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "downregulation of cytoplasmic transport" EXACT [GOC:TermGenie] +synonym: "inhibition of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "inhibition of cytoplasmic transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016482 ! cytosolic transport +relationship: negatively_regulates GO:0016482 ! cytosolic transport +created_by: jl +creation_date: 2014-11-24T13:38:26Z + +[Term] +id: GO:1903651 +name: positive regulation of cytoplasmic transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "activation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "activation of cytoplasmic transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic transport" EXACT [GOC:TermGenie] +synonym: "upregulation of cytoplasmic streaming" NARROW [GOC:TermGenie] +synonym: "upregulation of cytoplasmic transport" EXACT [GOC:TermGenie] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016482 ! cytosolic transport +relationship: positively_regulates GO:0016482 ! cytosolic transport +created_by: jl +creation_date: 2014-11-24T13:38:34Z + +[Term] +id: GO:1903652 +name: modulation by virus of host cytoplasmic transport +namespace: biological_process +def: "Modulation by an infecting virus of host cytoplasmic transport." [GO_REF:0000063, GOC:TermGenie, PMID:25049409] +synonym: "regulation by virus of host cytoplasmic streaming" EXACT [] +synonym: "regulation by virus of host cytoplasmic transport" EXACT [] +synonym: "viral modulation of host cytoplasmic trafficking" EXACT [] +is_a: GO:0019054 ! modulation by virus of host cellular process +is_a: GO:0052038 ! modulation by symbiont of host intracellular transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: regulates GO:0016482 ! cytosolic transport +created_by: jl +creation_date: 2014-11-24T17:22:04Z + +[Term] +id: GO:1903653 +name: modulation by symbiont of host cell motility +namespace: biological_process +def: "Modulation of host cell motility by a symbiont of that host." [GO_REF:0000063, GOC:TermGenie, PMID:25049409] +synonym: "modulation by symbiont of host cell locomotion" EXACT [] +synonym: "modulation by symbiont of host cell movement" RELATED [] +synonym: "regulation by symbiont of host cell motility" EXACT [] +is_a: GO:0044068 ! modulation by symbiont of host cellular process +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: regulates GO:0048870 ! cell motility +created_by: jl +creation_date: 2014-11-24T17:37:56Z + +[Term] +id: GO:1903654 +name: phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter +namespace: biological_process +def: "Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter." [GO_REF:0000060, GOC:TermGenie, PMID:19328067] +is_a: GO:0071620 ! phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +intersection_of: GO:0071620 ! phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +intersection_of: part_of GO:0032968 ! positive regulation of transcription elongation from RNA polymerase II promoter +relationship: part_of GO:0032968 ! positive regulation of transcription elongation from RNA polymerase II promoter +created_by: vw +creation_date: 2014-11-25T11:00:43Z + +[Term] +id: GO:1903655 +name: phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter +namespace: biological_process +def: "Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter." [GO_REF:0000060, GOC:TermGenie, PMID:19328067] +is_a: GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +intersection_of: GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +intersection_of: part_of GO:0032968 ! positive regulation of transcription elongation from RNA polymerase II promoter +relationship: part_of GO:0032968 ! positive regulation of transcription elongation from RNA polymerase II promoter +created_by: vw +creation_date: 2014-11-25T11:04:16Z + +[Term] +id: GO:1903656 +name: regulation of type IV pilus biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of type IV pilus biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0060491 ! regulation of cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043683 ! type IV pilus biogenesis +relationship: regulates GO:0043683 ! type IV pilus biogenesis +created_by: jl +creation_date: 2014-11-25T12:03:09Z + +[Term] +id: GO:1903657 +name: negative regulation of type IV pilus biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "down regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of TFP biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type 4 pilus biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbria assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbria biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbriae assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbriae biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbrial assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbrial biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbrium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV fimbrium biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV pilus biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of type IV pilus biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:1903656 ! regulation of type IV pilus biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043683 ! type IV pilus biogenesis +relationship: negatively_regulates GO:0043683 ! type IV pilus biogenesis +created_by: jl +creation_date: 2014-11-25T12:03:24Z + +[Term] +id: GO:1903658 +name: positive regulation of type IV pilus biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] +synonym: "activation of TFP biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type 4 pilus biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbria assembly" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbria biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbriae assembly" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbriae biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbrial assembly" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbrial biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbrium assembly" NARROW [GOC:TermGenie] +synonym: "activation of type IV fimbrium biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV pilus biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of type IV pilus biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of TFP biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type 4 pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbria assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbria biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbriae assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbriae biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbrial assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbrial biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbrium assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV fimbrium biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV pilus biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of type IV pilus biosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:1903656 ! regulation of type IV pilus biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043683 ! type IV pilus biogenesis +relationship: positively_regulates GO:0043683 ! type IV pilus biogenesis +created_by: jl +creation_date: 2014-11-25T12:03:34Z + +[Term] +id: GO:1903659 +name: regulation of complement-dependent cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity." [GO_REF:0000058, GOC:TermGenie, PMID:24280217] +is_a: GO:0031341 ! regulation of cell killing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097278 ! complement-dependent cytotoxicity +relationship: regulates GO:0097278 ! complement-dependent cytotoxicity +created_by: jl +creation_date: 2014-11-25T15:03:54Z + +[Term] +id: GO:1903660 +name: negative regulation of complement-dependent cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity." [GO_REF:0000058, GOC:TermGenie, PMID:24280217] +synonym: "down regulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +synonym: "down-regulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +synonym: "downregulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +synonym: "inhibition of complement-dependent cytotoxicity" NARROW [GOC:TermGenie] +is_a: GO:0031342 ! negative regulation of cell killing +is_a: GO:1903659 ! regulation of complement-dependent cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097278 ! complement-dependent cytotoxicity +relationship: negatively_regulates GO:0097278 ! complement-dependent cytotoxicity +created_by: jl +creation_date: 2014-11-25T15:04:02Z + +[Term] +id: GO:1903661 +name: positive regulation of complement-dependent cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity." [GO_REF:0000058, GOC:TermGenie, PMID:24280217] +synonym: "activation of complement-dependent cytotoxicity" NARROW [GOC:TermGenie] +synonym: "up regulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +synonym: "up-regulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +synonym: "upregulation of complement-dependent cytotoxicity" EXACT [GOC:TermGenie] +is_a: GO:0031343 ! positive regulation of cell killing +is_a: GO:1903659 ! regulation of complement-dependent cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097278 ! complement-dependent cytotoxicity +relationship: positively_regulates GO:0097278 ! complement-dependent cytotoxicity +created_by: jl +creation_date: 2014-11-25T15:04:11Z + +[Term] +id: GO:1903662 +name: L-altrarate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving L-altrarate." [GO_REF:0000068, GOC:TermGenie, PMID:17649980] +synonym: "L-altrarate(1-) metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019577 ! aldaric acid metabolic process +created_by: jl +creation_date: 2014-11-26T14:34:20Z + +[Term] +id: GO:1903663 +name: L-altrarate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of L-altrarate." [GO_REF:0000068, GOC:TermGenie, PMID:17649980] +synonym: "L-altrarate(1-) breakdown" EXACT [GOC:TermGenie] +synonym: "L-altrarate(1-) catabolism" EXACT [GOC:TermGenie] +synonym: "L-altrarate(1-) degradation" EXACT [GOC:TermGenie] +is_a: GO:0019579 ! aldaric acid catabolic process +is_a: GO:1903662 ! L-altrarate metabolic process +created_by: jl +creation_date: 2014-11-26T14:34:28Z + +[Term] +id: GO:1903664 +name: regulation of asexual reproduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of asexual reproduction." [GO_REF:0000058, GOC:TermGenie, PMID:24390142] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019954 ! asexual reproduction +relationship: regulates GO:0019954 ! asexual reproduction +created_by: pf +creation_date: 2014-11-26T21:13:24Z + +[Term] +id: GO:1903665 +name: negative regulation of asexual reproduction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction." [GO_REF:0000058, GOC:TermGenie, PMID:24390142] +synonym: "down regulation of asexual reproduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of asexual reproduction" EXACT [GOC:TermGenie] +synonym: "downregulation of asexual reproduction" EXACT [GOC:TermGenie] +synonym: "inhibition of asexual reproduction" NARROW [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1903664 ! regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019954 ! asexual reproduction +relationship: negatively_regulates GO:0019954 ! asexual reproduction +created_by: pf +creation_date: 2014-11-26T21:13:32Z + +[Term] +id: GO:1903666 +name: positive regulation of asexual reproduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of asexual reproduction." [GO_REF:0000058, GOC:TermGenie, PMID:24390142] +synonym: "activation of asexual reproduction" NARROW [GOC:TermGenie] +synonym: "up regulation of asexual reproduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of asexual reproduction" EXACT [GOC:TermGenie] +synonym: "upregulation of asexual reproduction" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1903664 ! regulation of asexual reproduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019954 ! asexual reproduction +relationship: positively_regulates GO:0019954 ! asexual reproduction +created_by: pf +creation_date: 2014-11-26T21:13:40Z + +[Term] +id: GO:1903667 +name: regulation of chemorepellent activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemorepellent activity." [GO_REF:0000059, GOC:TermGenie, PMID:22711818, PMID:24390142] +synonym: "regulation of chemorepellant activity" EXACT [GOC:TermGenie] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0050923 ! regulation of negative chemotaxis +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045499 ! chemorepellent activity +relationship: regulates GO:0045499 ! chemorepellent activity +created_by: pf +creation_date: 2014-11-26T23:58:33Z + +[Term] +id: GO:1903668 +name: negative regulation of chemorepellent activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity." [GO_REF:0000059, GOC:TermGenie, PMID:22711818, PMID:24390142] +synonym: "down regulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "down regulation of chemorepellent activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemorepellent activity" EXACT [GOC:TermGenie] +synonym: "downregulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "downregulation of chemorepellent activity" EXACT [GOC:TermGenie] +synonym: "inhibition of chemorepellant activity" NARROW [GOC:TermGenie] +synonym: "inhibition of chemorepellent activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of chemorepellant activity" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0050925 ! negative regulation of negative chemotaxis +is_a: GO:1900121 ! negative regulation of receptor binding +is_a: GO:1903667 ! regulation of chemorepellent activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045499 ! chemorepellent activity +relationship: negatively_regulates GO:0045499 ! chemorepellent activity +created_by: pf +creation_date: 2014-11-26T23:58:42Z + +[Term] +id: GO:1903669 +name: positive regulation of chemorepellent activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemorepellent activity." [GO_REF:0000059, GOC:TermGenie, PMID:22711818, PMID:24390142] +synonym: "activation of chemorepellant activity" NARROW [GOC:TermGenie] +synonym: "activation of chemorepellent activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "up regulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "up regulation of chemorepellent activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemorepellent activity" EXACT [GOC:TermGenie] +synonym: "upregulation of chemorepellant activity" EXACT [GOC:TermGenie] +synonym: "upregulation of chemorepellent activity" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0050924 ! positive regulation of negative chemotaxis +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:1903667 ! regulation of chemorepellent activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045499 ! chemorepellent activity +relationship: positively_regulates GO:0045499 ! chemorepellent activity +created_by: pf +creation_date: 2014-11-26T23:58:50Z + +[Term] +id: GO:1903670 +name: regulation of sprouting angiogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:16756958] +is_a: GO:0045765 ! regulation of angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002040 ! sprouting angiogenesis +relationship: regulates GO:0002040 ! sprouting angiogenesis +created_by: pga +creation_date: 2014-11-27T10:10:51Z + +[Term] +id: GO:1903671 +name: negative regulation of sprouting angiogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:16756958] +synonym: "down regulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of sprouting angiogenesis" NARROW [GOC:TermGenie] +is_a: GO:0016525 ! negative regulation of angiogenesis +is_a: GO:1903670 ! regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002040 ! sprouting angiogenesis +relationship: negatively_regulates GO:0002040 ! sprouting angiogenesis +created_by: pga +creation_date: 2014-11-27T10:10:59Z + +[Term] +id: GO:1903672 +name: positive regulation of sprouting angiogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:16756958] +synonym: "activation of sprouting angiogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of sprouting angiogenesis" EXACT [GOC:TermGenie] +is_a: GO:0045766 ! positive regulation of angiogenesis +is_a: GO:1903670 ! regulation of sprouting angiogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002040 ! sprouting angiogenesis +relationship: positively_regulates GO:0002040 ! sprouting angiogenesis +created_by: pga +creation_date: 2014-11-27T10:11:08Z + +[Term] +id: GO:1903673 +name: mitotic cleavage furrow formation +namespace: biological_process +def: "Any cleavage furrow formation that is involved in mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "cleavage furrow positioning involved in mitotic cell cycle" NARROW [GOC:TermGenie] +is_a: GO:0036089 ! cleavage furrow formation +is_a: GO:1902410 ! mitotic cytokinetic process +intersection_of: GO:0036089 ! cleavage furrow formation +intersection_of: part_of GO:0000278 ! mitotic cell cycle +created_by: jl +creation_date: 2014-11-27T15:32:18Z + +[Term] +id: GO:1903674 +name: regulation of cap-dependent translational initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cap-dependent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +is_a: GO:1904688 ! regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002191 ! cap-dependent translational initiation +relationship: regulates GO:0002191 ! cap-dependent translational initiation +created_by: bf +creation_date: 2014-11-27T19:50:23Z + +[Term] +id: GO:1903675 +name: negative regulation of cap-dependent translational initiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +synonym: "inhibition of cap-dependent translational initiation" NARROW [GOC:TermGenie] +is_a: GO:1903674 ! regulation of cap-dependent translational initiation +is_a: GO:1904689 ! negative regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002191 ! cap-dependent translational initiation +relationship: negatively_regulates GO:0002191 ! cap-dependent translational initiation +created_by: bf +creation_date: 2014-11-27T19:50:31Z + +[Term] +id: GO:1903676 +name: positive regulation of cap-dependent translational initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11959995] +synonym: "activation of cap-dependent translational initiation" NARROW [GOC:TermGenie] +synonym: "up regulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cap-dependent translational initiation" EXACT [GOC:TermGenie] +is_a: GO:1903674 ! regulation of cap-dependent translational initiation +is_a: GO:1904690 ! positive regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002191 ! cap-dependent translational initiation +relationship: positively_regulates GO:0002191 ! cap-dependent translational initiation +created_by: bf +creation_date: 2014-11-27T19:50:39Z + +[Term] +id: GO:1903677 +name: regulation of cap-independent translational initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cap-independent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +is_a: GO:1904688 ! regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002190 ! cap-independent translational initiation +relationship: regulates GO:0002190 ! cap-independent translational initiation +created_by: bf +creation_date: 2014-11-27T19:52:20Z + +[Term] +id: GO:1903678 +name: negative regulation of cap-independent translational initiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +synonym: "inhibition of cap-independent translational initiation" NARROW [GOC:TermGenie] +is_a: GO:1903677 ! regulation of cap-independent translational initiation +is_a: GO:1904689 ! negative regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002190 ! cap-independent translational initiation +relationship: negatively_regulates GO:0002190 ! cap-independent translational initiation +created_by: bf +creation_date: 2014-11-27T19:52:28Z + +[Term] +id: GO:1903679 +name: positive regulation of cap-independent translational initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11959995] +synonym: "activation of cap-independent translational initiation" NARROW [GOC:TermGenie] +synonym: "up regulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cap-independent translational initiation" EXACT [GOC:TermGenie] +is_a: GO:1903677 ! regulation of cap-independent translational initiation +is_a: GO:1904690 ! positive regulation of cytoplasmic translational initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002190 ! cap-independent translational initiation +relationship: positively_regulates GO:0002190 ! cap-independent translational initiation +created_by: bf +creation_date: 2014-11-27T19:52:36Z + +[Term] +id: GO:1903680 +name: acinar cell of sebaceous gland differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland." [GO_REF:0000086, GOC:TermGenie, PMID:17018284, PMID:18334552, PMID:19944183] +synonym: "sebocyte differentiation" EXACT [CL:0002140] +is_a: GO:0001949 ! sebaceous gland cell differentiation +is_a: GO:0090425 ! acinar cell differentiation +created_by: cls +creation_date: 2014-11-30T11:51:57Z + +[Term] +id: GO:1903681 +name: regulation of epithelial cell-cell adhesion involved in epithelium migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +is_a: GO:0022407 ! regulation of cell-cell adhesion +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +relationship: regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +created_by: als +creation_date: 2014-12-01T13:25:05Z + +[Term] +id: GO:1903682 +name: negative regulation of epithelial cell-cell adhesion involved in epithelium migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "down regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelial cell-cell adhesion involved in epithelium migration" NARROW [GOC:TermGenie] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903681 ! regulation of epithelial cell-cell adhesion involved in epithelium migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +relationship: negatively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +created_by: als +creation_date: 2014-12-01T13:25:14Z + +[Term] +id: GO:1903683 +name: positive regulation of epithelial cell-cell adhesion involved in epithelium migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "activation of epithelial cell-cell adhesion involved in epithelium migration" NARROW [GOC:TermGenie] +synonym: "up regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelial cell-cell adhesion involved in epithelium migration" EXACT [GOC:TermGenie] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903681 ! regulation of epithelial cell-cell adhesion involved in epithelium migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +relationship: positively_regulates GO:0090137 ! epithelial cell-cell adhesion involved in epithelium migration +created_by: als +creation_date: 2014-12-01T13:25:22Z + +[Term] +id: GO:1903684 +name: regulation of border follicle cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of border follicle cell migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "regulation of border cell migration" BROAD [GOC:TermGenie] +is_a: GO:0010632 ! regulation of epithelial cell migration +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:1905879 ! regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007298 ! border follicle cell migration +relationship: regulates GO:0007298 ! border follicle cell migration +created_by: als +creation_date: 2014-12-01T13:35:39Z + +[Term] +id: GO:1903687 +name: negative regulation of border follicle cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "inhibition of border follicle cell migration" NARROW [GOC:TermGenie] +is_a: GO:0010633 ! negative regulation of epithelial cell migration +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:1903684 ! regulation of border follicle cell migration +is_a: GO:1905880 ! negative regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007298 ! border follicle cell migration +relationship: negatively_regulates GO:0007298 ! border follicle cell migration +created_by: als +creation_date: 2014-12-01T13:41:05Z + +[Term] +id: GO:1903688 +name: positive regulation of border follicle cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of border follicle cell migration." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "activation of border follicle cell migration" NARROW [GOC:TermGenie] +is_a: GO:0010634 ! positive regulation of epithelial cell migration +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:1903684 ! regulation of border follicle cell migration +is_a: GO:1905881 ! positive regulation of oogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007298 ! border follicle cell migration +relationship: positively_regulates GO:0007298 ! border follicle cell migration +created_by: als +creation_date: 2014-12-01T13:41:19Z + +[Term] +id: GO:1903689 +name: regulation of wound healing, spreading of epidermal cells +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035313 ! wound healing, spreading of epidermal cells +relationship: regulates GO:0035313 ! wound healing, spreading of epidermal cells +created_by: als +creation_date: 2014-12-01T15:54:18Z + +[Term] +id: GO:1903690 +name: negative regulation of wound healing, spreading of epidermal cells +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "down regulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +synonym: "down-regulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +synonym: "downregulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +synonym: "inhibition of wound healing, spreading of epidermal cells" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:1903689 ! regulation of wound healing, spreading of epidermal cells +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035313 ! wound healing, spreading of epidermal cells +relationship: negatively_regulates GO:0035313 ! wound healing, spreading of epidermal cells +created_by: als +creation_date: 2014-12-01T15:54:27Z + +[Term] +id: GO:1903691 +name: positive regulation of wound healing, spreading of epidermal cells +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] +synonym: "activation of wound healing, spreading of epidermal cells" NARROW [GOC:TermGenie] +synonym: "up regulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +synonym: "up-regulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +synonym: "upregulation of wound healing, spreading of epidermal cells" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:1903689 ! regulation of wound healing, spreading of epidermal cells +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035313 ! wound healing, spreading of epidermal cells +relationship: positively_regulates GO:0035313 ! wound healing, spreading of epidermal cells +created_by: als +creation_date: 2014-12-01T15:54:35Z + +[Term] +id: GO:1903692 +name: methionine import across plasma membrane +namespace: biological_process +alt_id: GO:0044690 +def: "The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:17556368] +synonym: "methionine import" BROAD [] +synonym: "methionine import into cell" EXACT [] +is_a: GO:0015821 ! methionine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +created_by: jl +creation_date: 2012-08-15T14:54:38Z + +[Term] +id: GO:1903693 +name: regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation." [GO_REF:0000058, GOC:TermGenie, PMID:15713656] +synonym: "regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0071156 ! regulation of cell cycle arrest +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071851 ! mitotic G1 cell cycle arrest in response to nitrogen starvation +relationship: regulates GO:0071851 ! mitotic G1 cell cycle arrest in response to nitrogen starvation +created_by: al +creation_date: 2014-12-02T18:16:03Z + +[Term] +id: GO:1903694 +name: positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation." [GO_REF:0000058, GOC:TermGenie, PMID:15713656] +synonym: "activation of G1 mitotic cell cycle arrest in response to nitrogen starvation" NARROW [GOC:TermGenie] +synonym: "activation of mitotic G1 cell cycle arrest in response to nitrogen starvation" NARROW [GOC:TermGenie] +synonym: "positive regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "up regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "up-regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "upregulation of G1 mitotic cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic G1 cell cycle arrest in response to nitrogen starvation" EXACT [GOC:TermGenie] +is_a: GO:0071158 ! positive regulation of cell cycle arrest +is_a: GO:1903693 ! regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071851 ! mitotic G1 cell cycle arrest in response to nitrogen starvation +relationship: positively_regulates GO:0071851 ! mitotic G1 cell cycle arrest in response to nitrogen starvation +created_by: al +creation_date: 2014-12-02T18:16:16Z + +[Term] +id: GO:1903695 +name: MAPK cascade involved in ascospore formation +namespace: biological_process +def: "Any MAPK cascade that is involved in ascospore formation." [GO_REF:0000060, GOC:TermGenie, PMID:8443406] +synonym: "ERK/MAPK cascade involved in ascospore biosynthesis" NARROW [GOC:TermGenie] +synonym: "ERK/MAPK cascade involved in ascospore formation" NARROW [GOC:TermGenie] +synonym: "MAP kinase cascade involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "MAP kinase cascade involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "MAP kinase kinase kinase cascade involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "MAP kinase kinase kinase cascade involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "MAPK cascade involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "MAPK signal transduction involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "MAPK signal transduction involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "MAPK signaling involved in ascospore biosynthesis" RELATED [GOC:TermGenie] +synonym: "MAPK signaling involved in ascospore formation" RELATED [GOC:TermGenie] +synonym: "MAPK signalling involved in ascospore biosynthesis" RELATED [GOC:TermGenie] +synonym: "MAPK signalling involved in ascospore formation" RELATED [GOC:TermGenie] +synonym: "MAPKKK cascade during sporulation involved in ascospore biosynthesis" NARROW [GOC:TermGenie] +synonym: "MAPKKK cascade during sporulation involved in ascospore formation" NARROW [GOC:TermGenie] +synonym: "MAPKKK cascade involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "MAPKKK cascade involved in ascospore formation" EXACT [GOC:TermGenie] +synonym: "mitogen-activated protein kinase cascade involved in ascospore biosynthesis" EXACT [GOC:TermGenie] +synonym: "mitogen-activated protein kinase cascade involved in ascospore formation" EXACT [GOC:TermGenie] +is_a: GO:0000165 ! MAPK cascade +is_a: GO:1903046 ! meiotic cell cycle process +intersection_of: GO:0000165 ! MAPK cascade +intersection_of: part_of GO:0030437 ! ascospore formation +relationship: part_of GO:0030437 ! ascospore formation +created_by: al +creation_date: 2014-12-02T22:09:18Z + +[Term] +id: GO:1903696 +name: protein localization to horsetail-astral microtubule array +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array." [GO_REF:0000087, GOC:TermGenie, PMID:11907273] +synonym: "protein localisation in horsetail-astral microtubule array" EXACT [GOC:TermGenie] +synonym: "protein localisation to horsetail-astral microtubule array" EXACT [GOC:TermGenie] +synonym: "protein localization in horsetail-astral microtubule array" EXACT [GOC:TermGenie] +is_a: GO:0072699 ! protein localization to cortical microtubule cytoskeleton +created_by: mah +creation_date: 2014-12-03T10:58:18Z + +[Term] +id: GO:1903697 +name: negative regulation of microvillus assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] +synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of microvillus assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0032534 ! regulation of microvillus assembly +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030033 ! microvillus assembly +relationship: negatively_regulates GO:0030033 ! microvillus assembly +created_by: als +creation_date: 2014-12-03T11:45:08Z + +[Term] +id: GO:1903698 +name: positive regulation of microvillus assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] +synonym: "activation of microvillus assembly" NARROW [GOC:TermGenie] +synonym: "activation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of microvillus biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0032534 ! regulation of microvillus assembly +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030033 ! microvillus assembly +relationship: positively_regulates GO:0030033 ! microvillus assembly +created_by: als +creation_date: 2014-12-03T11:45:17Z + +[Term] +id: GO:1903699 +name: tarsal gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:20664693] +synonym: "gland of Meibom development" EXACT [GOC:TermGenie] +synonym: "glandula tarsales development" EXACT [GOC:TermGenie] +synonym: "Meibomian gland development" EXACT [GOC:TermGenie] +synonym: "tarsoconjunctival gland development" RELATED [GOC:TermGenie] +is_a: GO:0048733 ! sebaceous gland development +created_by: cls +creation_date: 2014-12-03T11:47:07Z + +[Term] +id: GO:1903700 +name: caecum development +namespace: biological_process +def: "The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] +synonym: "blind intestine development" RELATED [GOC:TermGenie] +synonym: "blindgut development" RELATED [GOC:TermGenie] +synonym: "caeca development" NARROW [GOC:TermGenie] +synonym: "ceca development" NARROW [GOC:TermGenie] +synonym: "cecum development" EXACT [GOC:TermGenie] +synonym: "intestinum caecum development" RELATED [GOC:TermGenie] +synonym: "intestinum crassum caecum development" EXACT [GOC:TermGenie] +synonym: "intestinum crassum cecum development" RELATED [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: cls +creation_date: 2014-12-03T12:05:00Z + +[Term] +id: GO:1903701 +name: substantia propria of cornea development +namespace: biological_process +def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382] +synonym: "corneal stroma development" EXACT [GOC:TermGenie] +synonym: "stroma of cornea development" EXACT [GOC:TermGenie] +synonym: "substantia propria development" RELATED [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: cls +creation_date: 2014-12-03T13:12:09Z + +[Term] +id: GO:1903702 +name: esophagus development +namespace: biological_process +def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] +synonym: "esophageal development" EXACT [MGI:csmith] +synonym: "gullet development" EXACT [GOC:TermGenie] +synonym: "oesophagus development" EXACT [GOC:TermGenie] +is_a: GO:0048513 ! animal organ development +created_by: cls +creation_date: 2014-12-03T14:41:30Z + +[Term] +id: GO:1903703 +name: enterocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte." [GO_REF:0000086, GOC:TermGenie, PMID:16782882, Wikipedia:List_of_intestinal_epithelial_differentiation_genes] +is_a: GO:0060575 ! intestinal epithelial cell differentiation +created_by: cls +creation_date: 2014-12-03T15:08:51Z + +[Term] +id: GO:1903704 +name: negative regulation of production of siRNA involved in RNA interference +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19701182] +synonym: "down regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "down regulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "down-regulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "downregulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "inhibition of production of guide RNAs involved in RNA interference" NARROW [GOC:TermGenie] +synonym: "inhibition of production of siRNA involved in RNA interference" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA interference, production of guide RNAs" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA interference, production of siRNA" NARROW [GOC:TermGenie] +synonym: "negative regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:0090065 ! regulation of production of siRNA involved in RNA interference +is_a: GO:1900369 ! negative regulation of RNA interference +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030422 ! production of siRNA involved in RNA interference +relationship: negatively_regulates GO:0030422 ! production of siRNA involved in RNA interference +created_by: nc +creation_date: 2014-12-03T15:13:22Z + +[Term] +id: GO:1903705 +name: positive regulation of production of siRNA involved in RNA interference +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19701182] +synonym: "activation of production of guide RNAs involved in RNA interference" NARROW [GOC:TermGenie] +synonym: "activation of production of siRNA involved in RNA interference" NARROW [GOC:TermGenie] +synonym: "activation of RNA interference, production of guide RNAs" NARROW [GOC:TermGenie] +synonym: "activation of RNA interference, production of siRNA" NARROW [GOC:TermGenie] +synonym: "positive regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "up regulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "up-regulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of production of guide RNAs involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "upregulation of production of siRNA involved in RNA interference" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA interference, production of guide RNAs" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA interference, production of siRNA" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:0090065 ! regulation of production of siRNA involved in RNA interference +is_a: GO:1900370 ! positive regulation of RNA interference +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030422 ! production of siRNA involved in RNA interference +relationship: positively_regulates GO:0030422 ! production of siRNA involved in RNA interference +created_by: nc +creation_date: 2014-12-03T15:13:30Z + +[Term] +id: GO:1903706 +name: regulation of hemopoiesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] +comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. +synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie] +is_a: GO:0002682 ! regulation of immune system process +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030097 ! hemopoiesis +relationship: regulates GO:0030097 ! hemopoiesis +created_by: pad +creation_date: 2014-12-04T15:34:13Z + +[Term] +id: GO:1903707 +name: negative regulation of hemopoiesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] +comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. +synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie] +synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie] +synonym: "inhibition of blood cell biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of blood cell formation" NARROW [GOC:TermGenie] +synonym: "inhibition of haemopoiesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hematopoiesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hemopoiesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030097 ! hemopoiesis +relationship: negatively_regulates GO:0030097 ! hemopoiesis +created_by: pad +creation_date: 2014-12-04T15:34:21Z + +[Term] +id: GO:1903708 +name: positive regulation of hemopoiesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] +comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. +synonym: "activation of blood cell biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of blood cell formation" NARROW [GOC:TermGenie] +synonym: "activation of haemopoiesis" NARROW [GOC:TermGenie] +synonym: "activation of hematopoiesis" NARROW [GOC:TermGenie] +synonym: "activation of hemopoiesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie] +synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie] +synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie] +is_a: GO:0002684 ! positive regulation of immune system process +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903706 ! regulation of hemopoiesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030097 ! hemopoiesis +relationship: positively_regulates GO:0030097 ! hemopoiesis +created_by: pad +creation_date: 2014-12-04T15:34:30Z + +[Term] +id: GO:1903709 +name: uterine gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340] +synonym: "endometrial gland development" EXACT [GOC:TermGenie] +synonym: "endometrium gland development" EXACT [GOC:TermGenie] +synonym: "glandulae uterinae development" RELATED [GOC:TermGenie] +synonym: "glandular part of endometrium development" RELATED [GOC:TermGenie] +synonym: "set of uterine glands development" RELATED [GOC:TermGenie] +synonym: "uterine glands development" EXACT [GOC:TermGenie] +synonym: "uterine glands set development" EXACT [GOC:TermGenie] +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0048732 ! gland development +created_by: cls +creation_date: 2014-12-04T18:57:21Z + +[Term] +id: GO:1903710 +name: spermine transmembrane transport +namespace: biological_process +def: "The process in which spermine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:15637075] +is_a: GO:0000296 ! spermine transport +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902047 ! polyamine transmembrane transport +created_by: vw +creation_date: 2014-12-06T08:11:32Z + +[Term] +id: GO:1903711 +name: spermidine transmembrane transport +namespace: biological_process +def: "The process in which spermidine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:15637075] +is_a: GO:0015848 ! spermidine transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902047 ! polyamine transmembrane transport +created_by: vw +creation_date: 2014-12-06T08:12:44Z + +[Term] +id: GO:1903712 +name: cysteine transmembrane transport +namespace: biological_process +def: "The directed movement of cysteine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:17435223] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0042883 ! cysteine transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: vw +creation_date: 2014-12-06T08:15:06Z + +[Term] +id: GO:1903713 +name: asparagine transmembrane transport +namespace: biological_process +def: "The directed movement of asparagine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:18503766] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0006867 ! asparagine transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: vw +creation_date: 2014-12-06T08:17:55Z + +[Term] +id: GO:1903714 +name: isoleucine transmembrane transport +namespace: biological_process +def: "The directed movement of isoleucine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:18503766] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015818 ! isoleucine transport +is_a: GO:0098655 ! cation transmembrane transport +created_by: vw +creation_date: 2014-12-06T08:19:05Z + +[Term] +id: GO:1903715 +name: regulation of aerobic respiration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aerobic respiration." [GO_REF:0000058, GOC:TermGenie, PMID:19266076] +is_a: GO:0043457 ! regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009060 ! aerobic respiration +relationship: regulates GO:0009060 ! aerobic respiration +created_by: al +creation_date: 2014-12-08T00:40:37Z + +[Term] +id: GO:1903716 +name: guanine transmembrane transport +namespace: biological_process +def: "The process in which guanine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:14998997] +is_a: GO:0015854 ! guanine transport +is_a: GO:1904823 ! purine nucleobase transmembrane transport +created_by: vw +creation_date: 2014-12-08T12:18:27Z + +[Term] +id: GO:1903717 +name: response to ammonia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonia stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1901698 ! response to nitrogen compound +created_by: ha +creation_date: 2014-12-08T14:55:44Z + +[Term] +id: GO:1903718 +name: cellular response to ammonia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonia stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1903717 ! response to ammonia +created_by: ha +creation_date: 2014-12-08T14:55:54Z + +[Term] +id: GO:1903719 +name: regulation of I-kappaB phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] +synonym: "regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0043122 ! regulation of I-kappaB kinase/NF-kappaB signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007252 ! I-kappaB phosphorylation +relationship: regulates GO:0007252 ! I-kappaB phosphorylation +property_value: RO:0002161 NCBITaxon:4751 +created_by: lb +creation_date: 2014-12-08T15:45:07Z + +[Term] +id: GO:1903720 +name: negative regulation of I-kappaB phosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] +synonym: "down regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "inhibition of I-kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of IkappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of IKB phosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of inhibitor of kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "inhibition of inhibitor of NF-kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0043124 ! negative regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:1903719 ! regulation of I-kappaB phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007252 ! I-kappaB phosphorylation +relationship: negatively_regulates GO:0007252 ! I-kappaB phosphorylation +created_by: lb +creation_date: 2014-12-08T15:45:16Z + +[Term] +id: GO:1903721 +name: positive regulation of I-kappaB phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] +synonym: "activation of I-kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of IkappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of IKB phosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of inhibitor of kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of inhibitor of NF-kappaB phosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of IKB phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:0043123 ! positive regulation of I-kappaB kinase/NF-kappaB signaling +is_a: GO:1903719 ! regulation of I-kappaB phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007252 ! I-kappaB phosphorylation +relationship: positively_regulates GO:0007252 ! I-kappaB phosphorylation +created_by: lb +creation_date: 2014-12-08T15:45:25Z + +[Term] +id: GO:1903722 +name: regulation of centriole elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of centriole elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:20616062] +is_a: GO:0046599 ! regulation of centriole replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061511 ! centriole elongation +relationship: regulates GO:0061511 ! centriole elongation +created_by: als +creation_date: 2014-12-09T16:36:02Z + +[Term] +id: GO:1903723 +name: negative regulation of centriole elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:20616062] +synonym: "down regulation of centriole elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of centriole elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of centriole elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of centriole elongation" NARROW [GOC:TermGenie] +is_a: GO:0046600 ! negative regulation of centriole replication +is_a: GO:1903722 ! regulation of centriole elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061511 ! centriole elongation +relationship: negatively_regulates GO:0061511 ! centriole elongation +created_by: als +creation_date: 2014-12-09T16:36:12Z + +[Term] +id: GO:1903724 +name: positive regulation of centriole elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of centriole elongation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:20616062] +synonym: "activation of centriole elongation" NARROW [GOC:TermGenie] +synonym: "up regulation of centriole elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of centriole elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of centriole elongation" EXACT [GOC:TermGenie] +is_a: GO:0046601 ! positive regulation of centriole replication +is_a: GO:1903722 ! regulation of centriole elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061511 ! centriole elongation +relationship: positively_regulates GO:0061511 ! centriole elongation +created_by: als +creation_date: 2014-12-09T16:36:20Z + +[Term] +id: GO:1903725 +name: regulation of phospholipid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10657240] +synonym: "regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0019220 ! regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006644 ! phospholipid metabolic process +relationship: regulates GO:0006644 ! phospholipid metabolic process +created_by: sl +creation_date: 2014-12-09T20:49:27Z + +[Term] +id: GO:1903726 +name: negative regulation of phospholipid metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10657240] +synonym: "down regulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of phospholipid metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of phospholipid metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045833 ! negative regulation of lipid metabolic process +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006644 ! phospholipid metabolic process +relationship: negatively_regulates GO:0006644 ! phospholipid metabolic process +created_by: sl +creation_date: 2014-12-09T20:49:35Z + +[Term] +id: GO:1903727 +name: positive regulation of phospholipid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10657240] +synonym: "activation of phospholipid metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of phospholipid metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipid metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipid metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045834 ! positive regulation of lipid metabolic process +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +is_a: GO:1903725 ! regulation of phospholipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006644 ! phospholipid metabolic process +relationship: positively_regulates GO:0006644 ! phospholipid metabolic process +created_by: sl +creation_date: 2014-12-09T20:49:44Z + +[Term] +id: GO:1903728 +name: luteal cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells." [GO_REF:0000086, GOC:TermGenie, MP:0001133] +synonym: "lutein cell differentiation" EXACT [CL:0000175] +is_a: GO:0030154 ! cell differentiation +created_by: cjm +creation_date: 2014-12-10T01:36:43Z + +[Term] +id: GO:1903729 +name: regulation of plasma membrane organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900] +synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie] +synonym: "regulation of plasma membrane organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007009 ! plasma membrane organization +relationship: regulates GO:0007009 ! plasma membrane organization +created_by: al +creation_date: 2014-12-10T18:59:44Z + +[Term] +id: GO:1903730 +name: regulation of phosphatidate phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:22334681, PMID:24876385, PMID:25359770] +comment: Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity +synonym: "regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008195 ! phosphatidate phosphatase activity +relationship: part_of GO:0010866 ! regulation of triglyceride biosynthetic process +relationship: part_of GO:0071071 ! regulation of phospholipid biosynthetic process +relationship: regulates GO:0008195 ! phosphatidate phosphatase activity +created_by: rn +creation_date: 2014-12-11T21:29:55Z + +[Term] +id: GO:1903740 +name: positive regulation of phosphatidate phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity." [GO_REF:0000059, GOC:rn, GOC:TermGenie, PMID:25359770] +synonym: "activation of 3-sn-phosphatidate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of acid phosphatidyl phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatic acid phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatic acid phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidate phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidic acid phosphatase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:1903730 ! regulation of phosphatidate phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008195 ! phosphatidate phosphatase activity +relationship: part_of GO:0010867 ! positive regulation of triglyceride biosynthetic process +relationship: part_of GO:0071073 ! positive regulation of phospholipid biosynthetic process +relationship: positively_regulates GO:0008195 ! phosphatidate phosphatase activity +created_by: tb +creation_date: 2014-12-11T23:37:44Z + +[Term] +id: GO:1903741 +name: negative regulation of phosphatidate phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity." [GO_REF:0000059, GOC:rn, GOC:TermGenie, PMID:22334681] +synonym: "down regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidate phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 3-sn-phosphatidate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of acid phosphatidyl phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatic acid phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatic acid phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidate phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidate phosphohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid phosphatase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3-sn-phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of acid phosphatidyl phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatic acid phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatic acid phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidate phosphohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidic acid phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0010923 ! negative regulation of phosphatase activity +is_a: GO:1903730 ! regulation of phosphatidate phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008195 ! phosphatidate phosphatase activity +relationship: negatively_regulates GO:0008195 ! phosphatidate phosphatase activity +relationship: part_of GO:0010868 ! negative regulation of triglyceride biosynthetic process +relationship: part_of GO:0071072 ! negative regulation of phospholipid biosynthetic process +created_by: tb +creation_date: 2014-12-11T23:37:54Z + +[Term] +id: GO:1903742 +name: regulation of anterograde synaptic vesicle transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:25329901] +subset: goslim_synapse +is_a: GO:1901608 ! regulation of vesicle transport along microtubule +is_a: GO:1902803 ! regulation of synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048490 ! anterograde synaptic vesicle transport +relationship: regulates GO:0048490 ! anterograde synaptic vesicle transport +created_by: kmv +creation_date: 2014-12-12T16:28:27Z + +[Term] +id: GO:1903743 +name: negative regulation of anterograde synaptic vesicle transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:25329901] +synonym: "down regulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "downregulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "inhibition of anterograde synaptic vesicle transport" NARROW [GOC:TermGenie] +is_a: GO:1901609 ! negative regulation of vesicle transport along microtubule +is_a: GO:1902804 ! negative regulation of synaptic vesicle transport +is_a: GO:1903742 ! regulation of anterograde synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048490 ! anterograde synaptic vesicle transport +relationship: negatively_regulates GO:0048490 ! anterograde synaptic vesicle transport +created_by: kmv +creation_date: 2014-12-12T16:28:37Z + +[Term] +id: GO:1903744 +name: positive regulation of anterograde synaptic vesicle transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:25329901] +synonym: "activation of anterograde synaptic vesicle transport" NARROW [GOC:TermGenie] +synonym: "up regulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +synonym: "upregulation of anterograde synaptic vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:1901610 ! positive regulation of vesicle transport along microtubule +is_a: GO:1902805 ! positive regulation of synaptic vesicle transport +is_a: GO:1903742 ! regulation of anterograde synaptic vesicle transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048490 ! anterograde synaptic vesicle transport +relationship: positively_regulates GO:0048490 ! anterograde synaptic vesicle transport +created_by: kmv +creation_date: 2014-12-12T16:28:46Z + +[Term] +id: GO:1903745 +name: negative regulation of pharyngeal pumping +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:25329901] +synonym: "down regulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "down regulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "down-regulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "down-regulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "downregulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "downregulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "inhibition of pharyngeal pumping" NARROW [GOC:TermGenie] +synonym: "inhibition of pumping behavior" RELATED [GOC:TermGenie] +synonym: "negative regulation of pumping behavior" RELATED [GOC:TermGenie] +is_a: GO:0043051 ! regulation of pharyngeal pumping +is_a: GO:1903999 ! negative regulation of eating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043050 ! pharyngeal pumping +relationship: negatively_regulates GO:0043050 ! pharyngeal pumping +created_by: kmv +creation_date: 2014-12-12T17:10:59Z + +[Term] +id: GO:1903746 +name: positive regulation of pharyngeal pumping +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pharyngeal pumping." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, pmid:25329901] +synonym: "activation of pharyngeal pumping" NARROW [GOC:TermGenie] +synonym: "activation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "positive regulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "up regulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "up regulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "up-regulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "up-regulation of pumping behavior" RELATED [GOC:TermGenie] +synonym: "upregulation of pharyngeal pumping" EXACT [GOC:TermGenie] +synonym: "upregulation of pumping behavior" RELATED [GOC:TermGenie] +is_a: GO:0043051 ! regulation of pharyngeal pumping +is_a: GO:1904000 ! positive regulation of eating behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043050 ! pharyngeal pumping +relationship: positively_regulates GO:0043050 ! pharyngeal pumping +created_by: kmv +creation_date: 2014-12-12T17:11:09Z + +[Term] +id: GO:1903747 +name: regulation of establishment of protein localization to mitochondrion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185] +synonym: "regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +is_a: GO:0070201 ! regulation of establishment of protein localization +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072655 ! establishment of protein localization to mitochondrion +relationship: regulates GO:0072655 ! establishment of protein localization to mitochondrion +created_by: krc +creation_date: 2014-12-12T22:18:09Z + +[Term] +id: GO:1903748 +name: negative regulation of establishment of protein localization to mitochondrion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185] +synonym: "down regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of protein localisation to mitochondrion" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of protein localization in mitochondrion" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of protein localization to mitochondrion" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1904950 ! negative regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072655 ! establishment of protein localization to mitochondrion +relationship: negatively_regulates GO:0072655 ! establishment of protein localization to mitochondrion +created_by: krc +creation_date: 2014-12-12T22:18:18Z + +[Term] +id: GO:1903749 +name: positive regulation of establishment of protein localization to mitochondrion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion." [GO_REF:0000058, GOC:TermGenie, PMID:16857185] +synonym: "activation of establishment of protein localisation to mitochondrion" NARROW [GOC:TermGenie] +synonym: "activation of establishment of protein localization in mitochondrion" NARROW [GOC:TermGenie] +synonym: "activation of establishment of protein localization to mitochondrion" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localisation to mitochondrion" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localization in mitochondrion" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localization to mitochondrion" EXACT [GOC:TermGenie] +is_a: GO:1903747 ! regulation of establishment of protein localization to mitochondrion +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1904951 ! positive regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072655 ! establishment of protein localization to mitochondrion +relationship: positively_regulates GO:0072655 ! establishment of protein localization to mitochondrion +created_by: krc +creation_date: 2014-12-12T22:18:26Z + +[Term] +id: GO:1903750 +name: regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide." [GO_REF:0000058, GOC:TermGenie, PMID:18681888] +synonym: "regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of hydrogen peroxide-induced apoptosis" BROAD [GOC:TermGenie] +synonym: "regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +is_a: GO:1901298 ! regulation of hydrogen peroxide-mediated programmed cell death +is_a: GO:1902175 ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +created_by: krc +creation_date: 2014-12-12T23:04:28Z + +[Term] +id: GO:1903751 +name: negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide." [GO_REF:0000058, GOC:TermGenie, PMID:18681888] +synonym: "down regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "down-regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "downregulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "inhibition of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to H2O2" NARROW [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "negative regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +is_a: GO:1901299 ! negative regulation of hydrogen peroxide-mediated programmed cell death +is_a: GO:1902176 ! negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903750 ! regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: negatively_regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +created_by: krc +creation_date: 2014-12-12T23:04:37Z + +[Term] +id: GO:1903752 +name: positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide." [GO_REF:0000058, GOC:TermGenie, PMID:18681888] +synonym: "activation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to H2O2" NARROW [GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "positive regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "up regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "up-regulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "upregulation of H2O2-induced intrinsic apoptotic signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to H2O2" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" EXACT [GOC:TermGenie] +is_a: GO:1901300 ! positive regulation of hydrogen peroxide-mediated programmed cell death +is_a: GO:1902177 ! positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:1903750 ! regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +relationship: positively_regulates GO:0036481 ! intrinsic apoptotic signaling pathway in response to hydrogen peroxide +created_by: krc +creation_date: 2014-12-12T23:04:46Z + +[Term] +id: GO:1903753 +name: negative regulation of p38MAPK cascade +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade." [GO_REF:0000058, GOC:TermGenie, PMID:18681888] +synonym: "down regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of p38MAPK cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of p38MAPK cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of p38MAPK cascade" EXACT [GOC:TermGenie] +synonym: "inhibition of p38 cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of p38 MAPK cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of p38MAPK cascade" NARROW [GOC:TermGenie] +synonym: "negative regulation of p38 cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of p38 MAPK cascade" EXACT [GOC:TermGenie] +is_a: GO:0032873 ! negative regulation of stress-activated MAPK cascade +is_a: GO:1900744 ! regulation of p38MAPK cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038066 ! p38MAPK cascade +relationship: negatively_regulates GO:0038066 ! p38MAPK cascade +created_by: krc +creation_date: 2014-12-12T23:09:26Z + +[Term] +id: GO:1903754 +name: cortical microtubule plus-end +namespace: cellular_component +def: "The plus-end of a cortical microtubule." [GO_REF:0000064, GOC:TermGenie, GOC:vw] +synonym: "cortical microtubule plus end" EXACT [] +is_a: GO:1904511 ! cytoplasmic microtubule plus-end +intersection_of: GO:0035371 ! microtubule plus-end +intersection_of: part_of GO:0055028 ! cortical microtubule +relationship: part_of GO:0055028 ! cortical microtubule +created_by: jl +creation_date: 2014-12-16T15:41:38Z + +[Term] +id: GO:1903755 +name: positive regulation of SUMO transferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of SUMO transferase activity." [GO_REF:0000059, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:19955185] +synonym: "activation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] +synonym: "activation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] +synonym: "activation of SUMO transferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] +synonym: "positive regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] +synonym: "up regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] +synonym: "up regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] +synonym: "up regulation of SUMO transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] +synonym: "up-regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of SUMO transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] +synonym: "upregulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] +synonym: "upregulation of SUMO transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0033235 ! positive regulation of protein sumoylation +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1903182 ! regulation of SUMO transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019789 ! SUMO transferase activity +relationship: positively_regulates GO:0019789 ! SUMO transferase activity +created_by: rl +creation_date: 2014-12-18T13:05:59Z + +[Term] +id: GO:1903759 +name: signal transduction involved in regulation of aerobic respiration +namespace: biological_process +def: "Any signal transduction that is involved in regulation of aerobic respiration." [GO_REF:0000060, GOC:TermGenie, PMID:19266076] +synonym: "signaling cascade involved in regulation of aerobic respiration" NARROW [GOC:TermGenie] +synonym: "signaling pathway involved in regulation of aerobic respiration" RELATED [GOC:TermGenie] +synonym: "signalling cascade involved in regulation of aerobic respiration" NARROW [GOC:TermGenie] +synonym: "signalling pathway involved in regulation of aerobic respiration" RELATED [GOC:TermGenie] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:1903715 ! regulation of aerobic respiration +relationship: part_of GO:1903715 ! regulation of aerobic respiration +created_by: al +creation_date: 2014-12-18T16:37:50Z + +[Term] +id: GO:1903760 +name: regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18337493] +synonym: "regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:1905024 ! regulation of membrane repolarization during ventricular cardiac muscle cell action potential +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +relationship: regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +created_by: rl +creation_date: 2014-12-19T12:01:59Z + +[Term] +id: GO:1903761 +name: negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18337493] +synonym: "down regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "down regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "down-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "downregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1903760 ! regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity +is_a: GO:1905025 ! negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +relationship: negatively_regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +created_by: rl +creation_date: 2014-12-19T12:02:09Z + +[Term] +id: GO:1903762 +name: positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18337493] +synonym: "activation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "upregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1903760 ! regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity +is_a: GO:1905026 ! positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +relationship: positively_regulates GO:1902282 ! voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization +created_by: rl +creation_date: 2014-12-19T12:02:18Z + +[Term] +id: GO:1903763 +name: gap junction channel activity involved in cell communication by electrical coupling +namespace: molecular_function +def: "Any gap junction channel activity that is involved in cell communication by electrical coupling." [GO_REF:0000061, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:24587307] +synonym: "connexin involved in cell communication by electrical coupling" RELATED [GOC:TermGenie] +synonym: "innexin channel activity involved in cell communication by electrical coupling" EXACT [GOC:TermGenie] +synonym: "innexin involved in cell communication by electrical coupling" NARROW [GOC:TermGenie] +is_a: GO:0005243 ! gap junction channel activity +intersection_of: GO:0005243 ! gap junction channel activity +intersection_of: part_of GO:0010644 ! cell communication by electrical coupling +relationship: part_of GO:0010644 ! cell communication by electrical coupling +created_by: rl +creation_date: 2014-12-19T15:43:16Z + +[Term] +id: GO:1903764 +name: regulation of potassium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1902302 +def: "Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19646991] +synonym: "regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "regulation of potassium export across plasma membrane" BROAD [GOC:TermGenie] +synonym: "regulation of potassium ion export" BROAD [] +is_a: GO:1901379 ! regulation of potassium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097623 ! potassium ion export across plasma membrane +relationship: regulates GO:0097623 ! potassium ion export across plasma membrane +created_by: rl +creation_date: 2013-07-17T16:39:53Z + +[Term] +id: GO:1903765 +name: negative regulation of potassium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1902303 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19646991] +synonym: "down regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "down regulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "down regulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "down-regulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "down-regulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of potassium export" BROAD [GOC:TermGenie] +synonym: "downregulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "downregulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of potassium export" NARROW [GOC:TermGenie] +synonym: "inhibition of potassium ion export" RELATED [GOC:TermGenie] +synonym: "inhibition of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "negative regulation of potassium ion export" BROAD [] +is_a: GO:1901380 ! negative regulation of potassium ion transmembrane transport +is_a: GO:1903764 ! regulation of potassium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097623 ! potassium ion export across plasma membrane +relationship: negatively_regulates GO:0097623 ! potassium ion export across plasma membrane +created_by: rl +creation_date: 2013-07-17T16:40:02Z + +[Term] +id: GO:1903766 +name: positive regulation of potassium ion export across plasma membrane +namespace: biological_process +alt_id: GO:1902304 +def: "Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19646991] +synonym: "activation of potassium export" RELATED [GOC:TermGenie] +synonym: "activation of potassium ion export" RELATED [GOC:TermGenie] +synonym: "activation of potassium ion export across plasma membrane" RELATED [GOC:TermGenie] +synonym: "positive regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "positive regulation of potassium ion export" BROAD [] +synonym: "up regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "up regulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "up regulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of potassium export" BROAD [GOC:TermGenie] +synonym: "up-regulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "up-regulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of potassium export" BROAD [GOC:TermGenie] +synonym: "upregulation of potassium ion export" BROAD [GOC:TermGenie] +synonym: "upregulation of potassium ion export across plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:1901381 ! positive regulation of potassium ion transmembrane transport +is_a: GO:1903764 ! regulation of potassium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097623 ! potassium ion export across plasma membrane +relationship: positively_regulates GO:0097623 ! potassium ion export across plasma membrane +created_by: rl +creation_date: 2013-07-17T16:40:10Z + +[Term] +id: GO:1903767 +name: sweet taste receptor complex +namespace: cellular_component +def: "A protein complex which is capable of sweet taste receptor activity." [GO_REF:0000088, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16720576] +is_a: GO:1903768 ! taste receptor complex +created_by: rl +creation_date: 2014-12-22T16:49:24Z + +[Term] +id: GO:1903768 +name: taste receptor complex +namespace: cellular_component +def: "A protein complex which is capable of taste receptor activity." [GO_REF:0000088, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16720576] +is_a: GO:0043235 ! receptor complex +created_by: rl +creation_date: 2014-12-22T16:53:45Z + +[Term] +id: GO:1903769 +name: negative regulation of cell proliferation in bone marrow +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow." [GO_REF:0000058, GOC:TermGenie, PMID:9241534] +synonym: "down regulation of bone marrow cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of cell proliferation in bone marrow" EXACT [GOC:TermGenie] +synonym: "down-regulation of bone marrow cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation in bone marrow" EXACT [GOC:TermGenie] +synonym: "downregulation of bone marrow cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation in bone marrow" EXACT [GOC:TermGenie] +synonym: "inhibition of bone marrow cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of cell proliferation in bone marrow" NARROW [GOC:TermGenie] +synonym: "negative regulation of bone marrow cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0071863 ! regulation of cell proliferation in bone marrow +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071838 ! cell proliferation in bone marrow +relationship: negatively_regulates GO:0071838 ! cell proliferation in bone marrow +created_by: sl +creation_date: 2014-12-29T19:46:26Z + +[Term] +id: GO:1903770 +name: negative regulation of beta-galactosidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:11927518] +synonym: "down regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "down regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "down regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "down regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "down regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "down regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "down regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "down regulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "down-regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "down-regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "down-regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "down-regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "down-regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "down-regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "down-regulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "downregulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "downregulation of lactozym" RELATED [GOC:TermGenie] +synonym: "downregulation of maxilact" RELATED [GOC:TermGenie] +synonym: "downregulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "downregulation of S 2107" RELATED [GOC:TermGenie] +synonym: "downregulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "downregulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of beta-D-galactanase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-D-galactoside galactohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-D-lactosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-galactosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-lactosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of exo-(1->4)-beta-D-galactanase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrolact" RELATED [GOC:TermGenie] +synonym: "inhibition of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "inhibition of lactozym" RELATED [GOC:TermGenie] +synonym: "inhibition of maxilact" RELATED [GOC:TermGenie] +synonym: "inhibition of oryzatym" RELATED [GOC:TermGenie] +synonym: "inhibition of S 2107" RELATED [GOC:TermGenie] +synonym: "inhibition of sumiklat" RELATED [GOC:TermGenie] +synonym: "inhibition of trilactase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "negative regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "negative regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "negative regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "negative regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "negative regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "negative regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "negative regulation of trilactase activity" EXACT [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004565 ! beta-galactosidase activity +relationship: negatively_regulates GO:0004565 ! beta-galactosidase activity +created_by: nc +creation_date: 2015-01-06T10:53:22Z + +[Term] +id: GO:1903771 +name: positive regulation of beta-galactosidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:11927518] +synonym: "activation of beta-D-galactanase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-D-galactoside galactohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-D-lactosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-galactosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-lactosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of exo-(1->4)-beta-D-galactanase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrolact" RELATED [GOC:TermGenie] +synonym: "activation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "activation of lactozym" RELATED [GOC:TermGenie] +synonym: "activation of maxilact" RELATED [GOC:TermGenie] +synonym: "activation of oryzatym" RELATED [GOC:TermGenie] +synonym: "activation of S 2107" RELATED [GOC:TermGenie] +synonym: "activation of sumiklat" RELATED [GOC:TermGenie] +synonym: "activation of trilactase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "positive regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "positive regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "positive regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "positive regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "positive regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "positive regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "positive regulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "up regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "up regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "up regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "up regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "up regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "up regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "up regulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "up-regulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "up-regulation of lactozym" RELATED [GOC:TermGenie] +synonym: "up-regulation of maxilact" RELATED [GOC:TermGenie] +synonym: "up-regulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "up-regulation of S 2107" RELATED [GOC:TermGenie] +synonym: "up-regulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "up-regulation of trilactase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-galactosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-lactosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrolact" RELATED [GOC:TermGenie] +synonym: "upregulation of lactose hydrolysis" RELATED [GOC:TermGenie] +synonym: "upregulation of lactozym" RELATED [GOC:TermGenie] +synonym: "upregulation of maxilact" RELATED [GOC:TermGenie] +synonym: "upregulation of oryzatym" RELATED [GOC:TermGenie] +synonym: "upregulation of S 2107" RELATED [GOC:TermGenie] +synonym: "upregulation of sumiklat" RELATED [GOC:TermGenie] +synonym: "upregulation of trilactase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004565 ! beta-galactosidase activity +relationship: positively_regulates GO:0004565 ! beta-galactosidase activity +created_by: nc +creation_date: 2015-01-06T10:53:32Z + +[Term] +id: GO:1903772 +name: regulation of viral budding via host ESCRT complex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24878737] +synonym: "regulation of host-assisted viral budding" BROAD [GOC:TermGenie] +synonym: "regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0039702 ! viral budding via host ESCRT complex +relationship: regulates GO:0039702 ! viral budding via host ESCRT complex +created_by: als +creation_date: 2015-01-06T16:20:43Z + +[Term] +id: GO:1903773 +name: negative regulation of viral budding via host ESCRT complex +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24878737] +synonym: "down regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "down regulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "down-regulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +synonym: "downregulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "downregulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +synonym: "inhibition of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "inhibition of viral budding via host ESCRT complex" NARROW [GOC:TermGenie] +synonym: "negative regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +is_a: GO:1903772 ! regulation of viral budding via host ESCRT complex +is_a: GO:1903901 ! negative regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0039702 ! viral budding via host ESCRT complex +relationship: negatively_regulates GO:0039702 ! viral budding via host ESCRT complex +created_by: als +creation_date: 2015-01-06T16:20:53Z + +[Term] +id: GO:1903774 +name: positive regulation of viral budding via host ESCRT complex +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24878737] +synonym: "activation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "activation of viral budding via host ESCRT complex" NARROW [GOC:TermGenie] +synonym: "positive regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "up regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "up regulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "up-regulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +synonym: "upregulation of viral budding through the ESCRT machinery" RELATED [GOC:TermGenie] +synonym: "upregulation of viral budding via host ESCRT complex" EXACT [GOC:TermGenie] +is_a: GO:1903772 ! regulation of viral budding via host ESCRT complex +is_a: GO:1903902 ! positive regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0039702 ! viral budding via host ESCRT complex +relationship: positively_regulates GO:0039702 ! viral budding via host ESCRT complex +created_by: als +creation_date: 2015-01-06T16:21:02Z + +[Term] +id: GO:1903775 +name: regulation of DNA double-strand break processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA double-strand break processing." [GO_REF:0000058, GOC:TermGenie, PMID:25203555] +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000729 ! DNA double-strand break processing +relationship: regulates GO:0000729 ! DNA double-strand break processing +created_by: al +creation_date: 2015-01-06T17:08:15Z + +[Term] +id: GO:1903776 +name: regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends." [GO_REF:0000058, GOC:TermGenie, PMID:25203555] +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000736 ! double-strand break repair via single-strand annealing, removal of nonhomologous ends +relationship: regulates GO:0000736 ! double-strand break repair via single-strand annealing, removal of nonhomologous ends +created_by: al +creation_date: 2015-01-06T17:08:24Z + +[Term] +id: GO:1903777 +name: melibiose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with melibiose." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:11471732] +is_a: GO:0048030 ! disaccharide binding +created_by: mr +creation_date: 2015-01-06T21:05:29Z + +[Term] +id: GO:1903778 +name: protein localization to vacuolar membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562] +synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:0072665 ! protein localization to vacuole +created_by: mah +creation_date: 2015-01-07T13:15:54Z + +[Term] +id: GO:1903779 +name: regulation of cardiac conduction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] +is_a: GO:0008016 ! regulation of heart contraction +is_a: GO:0023051 ! regulation of signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061337 ! cardiac conduction +relationship: regulates GO:0061337 ! cardiac conduction +created_by: rph +creation_date: 2015-01-07T13:20:11Z + +[Term] +id: GO:1903780 +name: negative regulation of cardiac conduction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] +synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac conduction" NARROW [GOC:TermGenie] +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061337 ! cardiac conduction +relationship: negatively_regulates GO:0061337 ! cardiac conduction +created_by: rph +creation_date: 2015-01-07T13:20:20Z + +[Term] +id: GO:1903781 +name: positive regulation of cardiac conduction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] +synonym: "activation of cardiac conduction" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie] +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903779 ! regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061337 ! cardiac conduction +relationship: positively_regulates GO:0061337 ! cardiac conduction +created_by: rph +creation_date: 2015-01-07T13:20:28Z + +[Term] +id: GO:1903782 +name: regulation of sodium ion import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] +is_a: GO:1902305 ! regulation of sodium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098719 ! sodium ion import across plasma membrane +relationship: regulates GO:0098719 ! sodium ion import across plasma membrane +created_by: nc +creation_date: 2015-01-07T16:48:43Z + +[Term] +id: GO:1903783 +name: negative regulation of sodium ion import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] +synonym: "down regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of sodium ion import across plasma membrane" NARROW [GOC:TermGenie] +is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport +is_a: GO:1903782 ! regulation of sodium ion import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098719 ! sodium ion import across plasma membrane +relationship: negatively_regulates GO:0098719 ! sodium ion import across plasma membrane +created_by: nc +creation_date: 2015-01-07T16:48:51Z + +[Term] +id: GO:1903784 +name: positive regulation of sodium ion import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:19376779] +synonym: "activation of sodium ion import across plasma membrane" NARROW [GOC:TermGenie] +synonym: "up regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of sodium ion import across plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport +is_a: GO:1903782 ! regulation of sodium ion import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098719 ! sodium ion import across plasma membrane +relationship: positively_regulates GO:0098719 ! sodium ion import across plasma membrane +created_by: nc +creation_date: 2015-01-07T16:49:00Z + +[Term] +id: GO:1903785 +name: L-valine transmembrane transport +namespace: biological_process +def: "The directed movement of L-valine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:20944394] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015829 ! valine transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: al +creation_date: 2015-01-08T14:50:32Z + +[Term] +id: GO:1903786 +name: regulation of glutathione biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutathione biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "regulation of glutathione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051193 ! regulation of cofactor metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006750 ! glutathione biosynthetic process +relationship: regulates GO:0006750 ! glutathione biosynthetic process +created_by: bf +creation_date: 2015-01-08T17:14:49Z + +[Term] +id: GO:1903787 +name: negative regulation of glutathione biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "down regulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "downregulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of glutathione anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of glutathione biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of glutathione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of glutathione formation" NARROW [GOC:TermGenie] +synonym: "inhibition of glutathione synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutathione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051195 ! negative regulation of cofactor metabolic process +is_a: GO:1903786 ! regulation of glutathione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006750 ! glutathione biosynthetic process +relationship: negatively_regulates GO:0006750 ! glutathione biosynthetic process +created_by: bf +creation_date: 2015-01-08T17:14:59Z + +[Term] +id: GO:1903788 +name: positive regulation of glutathione biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of glutathione anabolism" NARROW [GOC:TermGenie] +synonym: "activation of glutathione biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of glutathione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of glutathione formation" NARROW [GOC:TermGenie] +synonym: "activation of glutathione synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "up regulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutathione synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione formation" EXACT [GOC:TermGenie] +synonym: "upregulation of glutathione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:0051194 ! positive regulation of cofactor metabolic process +is_a: GO:1903786 ! regulation of glutathione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006750 ! glutathione biosynthetic process +relationship: positively_regulates GO:0006750 ! glutathione biosynthetic process +created_by: bf +creation_date: 2015-01-08T17:15:07Z + +[Term] +id: GO:1903789 +name: regulation of amino acid transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814] +synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie] +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003333 ! amino acid transmembrane transport +relationship: regulates GO:0003333 ! amino acid transmembrane transport +created_by: al +creation_date: 2015-01-08T17:42:18Z + +[Term] +id: GO:1903790 +name: guanine nucleotide transmembrane transport +namespace: biological_process +def: "The process in which a guanyl nucleotide is transported across a membrane." [GO_REF:0000069, GOC:dph, GOC:TermGenie, GOC:vw, PMID:25320081] +synonym: "guanyl nucleotide transmembrane transport" EXACT [] +is_a: GO:0001408 ! guanine nucleotide transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +created_by: dph +creation_date: 2015-01-10T13:51:54Z + +[Term] +id: GO:1903791 +name: uracil transmembrane transport +namespace: biological_process +def: "The process in which uracil is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:8948441] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015857 ! uracil transport +is_a: GO:1904082 ! pyrimidine nucleobase transmembrane transport +created_by: vw +creation_date: 2015-01-12T10:15:25Z + +[Term] +id: GO:1903792 +name: negative regulation of anion transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anion transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] +synonym: "down regulation of anion transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of anion transport" EXACT [GOC:TermGenie] +synonym: "downregulation of anion transport" EXACT [GOC:TermGenie] +synonym: "inhibition of anion transport" NARROW [GOC:TermGenie] +is_a: GO:0043271 ! negative regulation of ion transport +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006820 ! anion transport +relationship: negatively_regulates GO:0006820 ! anion transport +created_by: sl +creation_date: 2015-01-12T21:50:20Z + +[Term] +id: GO:1903793 +name: positive regulation of anion transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anion transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] +synonym: "activation of anion transport" NARROW [GOC:TermGenie] +synonym: "up regulation of anion transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of anion transport" EXACT [GOC:TermGenie] +synonym: "upregulation of anion transport" EXACT [GOC:TermGenie] +is_a: GO:0043270 ! positive regulation of ion transport +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006820 ! anion transport +relationship: positively_regulates GO:0006820 ! anion transport +created_by: sl +creation_date: 2015-01-12T21:50:30Z + +[Term] +id: GO:1903794 +name: cortisol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cortisol." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:18483153] +is_a: GO:0008144 ! drug binding +is_a: GO:0043178 ! alcohol binding +is_a: GO:1990239 ! steroid hormone binding +created_by: mr +creation_date: 2015-01-14T19:02:31Z + +[Term] +id: GO:1903795 +name: regulation of inorganic anion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] +synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098661 ! inorganic anion transmembrane transport +relationship: regulates GO:0098661 ! inorganic anion transmembrane transport +created_by: sl +creation_date: 2015-01-14T21:44:49Z + +[Term] +id: GO:1903796 +name: negative regulation of inorganic anion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] +synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "inhibition of inorganic anion membrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "inhibition of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport +relationship: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport +created_by: sl +creation_date: 2015-01-14T21:44:59Z + +[Term] +id: GO:1903797 +name: positive regulation of inorganic anion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] +synonym: "activation of inorganic anion membrane transport" NARROW [GOC:TermGenie] +synonym: "activation of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "activation of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098661 ! inorganic anion transmembrane transport +relationship: positively_regulates GO:0098661 ! inorganic anion transmembrane transport +created_by: sl +creation_date: 2015-01-14T21:45:08Z + +[Term] +id: GO:1903798 +name: regulation of production of miRNAs involved in gene silencing by miRNA +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "regulation of microRNA processing" BROAD [GOC:TermGenie] +synonym: "regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +is_a: GO:0060964 ! regulation of gene silencing by miRNA +is_a: GO:0070920 ! regulation of production of small RNA involved in gene silencing by RNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +relationship: regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +created_by: rph +creation_date: 2015-01-15T13:58:12Z + +[Term] +id: GO:1903799 +name: negative regulation of production of miRNAs involved in gene silencing by miRNA +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "down regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "down regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "down regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "down regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "down regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "down regulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "down-regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "down-regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "down-regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "down-regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "downregulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "downregulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "downregulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "downregulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "downregulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "downregulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "inhibition of gene silencing by miRNA, production of miRNAs" NARROW [GOC:TermGenie] +synonym: "inhibition of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "inhibition of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "inhibition of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of microRNA-mediated gene silencing, production of microRNAs" NARROW [GOC:TermGenie] +synonym: "inhibition of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of miRNA processing" NARROW [GOC:TermGenie] +synonym: "inhibition of miRNA-mediated gene silencing, production of miRNAs" NARROW [GOC:TermGenie] +synonym: "inhibition of production of microRNAs involved in gene silencing by microRNA" NARROW [GOC:TermGenie] +synonym: "inhibition of production of miRNAs involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "negative regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "negative regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "negative regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "negative regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "negative regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:0060965 ! negative regulation of gene silencing by miRNA +is_a: GO:1903798 ! regulation of production of miRNAs involved in gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +relationship: negatively_regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +created_by: rph +creation_date: 2015-01-15T13:58:22Z + +[Term] +id: GO:1903800 +name: positive regulation of production of miRNAs involved in gene silencing by miRNA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "activation of gene silencing by miRNA, production of miRNAs" NARROW [GOC:TermGenie] +synonym: "activation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "activation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "activation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "activation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "activation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "activation of microRNA-mediated gene silencing, production of microRNAs" NARROW [GOC:TermGenie] +synonym: "activation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "activation of miRNA processing" NARROW [GOC:TermGenie] +synonym: "activation of miRNA-mediated gene silencing, production of miRNAs" NARROW [GOC:TermGenie] +synonym: "activation of production of microRNAs involved in gene silencing by microRNA" NARROW [GOC:TermGenie] +synonym: "activation of production of miRNAs involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "positive regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "positive regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "positive regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "positive regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "positive regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "up regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "up regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "up regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "up regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "up-regulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "up-regulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "up-regulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "up-regulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of gene silencing by miRNA, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "upregulation of microRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of microRNA biosynthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of microRNA biosynthetic process" RELATED [GOC:TermGenie] +synonym: "upregulation of microRNA metabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of microRNA metabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of microRNA-mediated gene silencing, production of microRNAs" EXACT [GOC:TermGenie] +synonym: "upregulation of miRNA biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of miRNA processing" EXACT [GOC:TermGenie] +synonym: "upregulation of miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:TermGenie] +synonym: "upregulation of production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of production of miRNAs involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1903798 ! regulation of production of miRNAs involved in gene silencing by miRNA +is_a: GO:2000637 ! positive regulation of gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +relationship: positively_regulates GO:0035196 ! production of miRNAs involved in gene silencing by miRNA +created_by: rph +creation_date: 2015-01-15T13:58:31Z + +[Term] +id: GO:1903801 +name: L-leucine import across plasma membrane +namespace: biological_process +alt_id: GO:0060356 +def: "The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-leucine import" BROAD [] +synonym: "L-leucine import into cell" EXACT [] +synonym: "L-leucine uptake" NARROW [] +synonym: "leucine import" BROAD [] +synonym: "leucine uptake" EXACT [] +is_a: GO:0098713 ! leucine import across plasma membrane +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: mah +creation_date: 2015-01-16T14:34:46Z + +[Term] +id: GO:1903803 +name: L-glutamine import across plasma membrane +namespace: biological_process +alt_id: GO:0036229 +def: "The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-glutamine import" BROAD [] +synonym: "L-glutamine import into cell" EXACT [] +synonym: "L-glutamine uptake" EXACT [GOC:bf] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0006868 ! glutamine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: bf +creation_date: 2012-05-11T10:46:21Z + +[Term] +id: GO:1903804 +name: glycine import across plasma membrane +namespace: biological_process +alt_id: GO:0036233 +def: "The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "glycine import" BROAD [] +synonym: "glycine import into cell" EXACT [] +is_a: GO:0001504 ! neurotransmitter uptake +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015816 ! glycine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: bf +creation_date: 2012-05-11T01:16:45Z + +[Term] +id: GO:1903805 +name: L-valine import across plasma membrane +namespace: biological_process +alt_id: GO:0090468 +def: "The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-valine import into cell" EXACT [] +synonym: "valine import" NARROW [] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1903785 ! L-valine transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:28:58Z + +[Term] +id: GO:1903806 +name: L-isoleucine import across plasma membrane +namespace: biological_process +alt_id: GO:0090476 +alt_id: GO:0090477 +def: "The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "isoleucine import" BROAD [] +synonym: "L-isoleucine import" BROAD [] +synonym: "L-isoleucine import into cell" EXACT [] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +is_a: GO:1903714 ! isoleucine transmembrane transport +created_by: tb +creation_date: 2012-10-01T11:10:51Z + +[Term] +id: GO:1903807 +name: L-threonine import across plasma membrane +namespace: biological_process +alt_id: GO:0036231 +def: "The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-threonine import" BROAD [] +synonym: "L-threonine import into cell" EXACT [] +synonym: "L-threonine uptake" EXACT [GOC:bf] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015826 ! threonine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: bf +creation_date: 2012-05-11T10:46:21Z + +[Term] +id: GO:1903808 +name: L-tyrosine import across plasma membrane +namespace: biological_process +alt_id: GO:0036232 +def: "The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-tyrosine import" BROAD [] +synonym: "L-tyrosine import into cell" EXACT [] +synonym: "L-tyrosine uptake" EXACT [GOC:bf] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015828 ! tyrosine transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: bf +creation_date: 2012-05-11T10:46:21Z + +[Term] +id: GO:1903810 +name: L-histidine import across plasma membrane +namespace: biological_process +alt_id: GO:0061460 +alt_id: GO:0090466 +def: "The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "histidine import" BROAD [] +synonym: "L-histidine import" BROAD [] +synonym: "L-histidine import into cell" EXACT [] +is_a: GO:0089709 ! L-histidine transmembrane transport +is_a: GO:0089718 ! amino acid import across plasma membrane +created_by: dph +creation_date: 2012-10-05T10:20:50Z + +[Term] +id: GO:1903811 +name: L-asparagine import across plasma membrane +namespace: biological_process +alt_id: GO:0090469 +def: "The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "asparagine import" BROAD [] +synonym: "L-asparagine import into cell" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +is_a: GO:1903713 ! asparagine transmembrane transport +created_by: tb +creation_date: 2012-09-24T14:28:58Z + +[Term] +id: GO:1903812 +name: L-serine import across plasma membrane +namespace: biological_process +def: "The directed movement of L-serine into a cell." [GO_REF:0000075, GOC:TermGenie, PMID:23895341] +synonym: "L-serine import into cell" EXACT [] +is_a: GO:0015825 ! L-serine transport +is_a: GO:0098718 ! serine import across plasma membrane +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: mah +creation_date: 2015-01-16T14:36:29Z + +[Term] +id: GO:1903814 +name: regulation of collecting lymphatic vessel constriction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction." [GO_REF:0000058, GOC:TermGenie, PMID:23897233] +synonym: "regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +is_a: GO:0044057 ! regulation of system process +is_a: GO:0090066 ! regulation of anatomical structure size +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990192 ! collecting lymphatic vessel constriction +relationship: regulates GO:1990192 ! collecting lymphatic vessel constriction +created_by: sl +creation_date: 2015-01-16T17:01:49Z + +[Term] +id: GO:1903815 +name: negative regulation of collecting lymphatic vessel constriction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction." [GO_REF:0000058, GOC:TermGenie, PMID:23897233] +synonym: "down regulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "down regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "down-regulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "down-regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "downregulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "downregulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "inhibition of collecting lymphatic vessel constriction" NARROW [GOC:TermGenie] +synonym: "inhibition of lymphatic vessel myogenic constriction" NARROW [GOC:TermGenie] +synonym: "negative regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1903814 ! regulation of collecting lymphatic vessel constriction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990192 ! collecting lymphatic vessel constriction +relationship: negatively_regulates GO:1990192 ! collecting lymphatic vessel constriction +created_by: sl +creation_date: 2015-01-16T17:01:58Z + +[Term] +id: GO:1903816 +name: positive regulation of collecting lymphatic vessel constriction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction." [GO_REF:0000058, GOC:TermGenie, PMID:23897233] +synonym: "activation of collecting lymphatic vessel constriction" NARROW [GOC:TermGenie] +synonym: "activation of lymphatic vessel myogenic constriction" NARROW [GOC:TermGenie] +synonym: "positive regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "up regulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "up regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "up-regulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "up-regulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +synonym: "upregulation of collecting lymphatic vessel constriction" EXACT [GOC:TermGenie] +synonym: "upregulation of lymphatic vessel myogenic constriction" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1903814 ! regulation of collecting lymphatic vessel constriction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990192 ! collecting lymphatic vessel constriction +relationship: positively_regulates GO:1990192 ! collecting lymphatic vessel constriction +created_by: sl +creation_date: 2015-01-16T17:02:08Z + +[Term] +id: GO:1903817 +name: negative regulation of voltage-gated potassium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:19219384] +synonym: "down regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage gated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-dependent potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium ion channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-sensitive potassium channel" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005249 ! voltage-gated potassium channel activity +relationship: negatively_regulates GO:0005249 ! voltage-gated potassium channel activity +created_by: sl +creation_date: 2015-01-16T17:22:08Z + +[Term] +id: GO:1903818 +name: positive regulation of voltage-gated potassium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:19219384] +synonym: "activation of voltage gated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-dependent potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated potassium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated potassium ion channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-sensitive potassium channel" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] +is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005249 ! voltage-gated potassium channel activity +relationship: positively_regulates GO:0005249 ! voltage-gated potassium channel activity +created_by: sl +creation_date: 2015-01-16T17:22:18Z + +[Term] +id: GO:1903819 +name: detection of stimulus involved in mitotic cytokinesis checkpoint +namespace: biological_process +def: "Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "perception of stimulus involved in mitotic cytokinesis checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus detection involved in mitotic cytokinesis checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in mitotic cytokinesis checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072397 ! detection of stimulus involved in cytokinesis checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044878 ! mitotic cytokinesis checkpoint +relationship: part_of GO:0044878 ! mitotic cytokinesis checkpoint +created_by: jl +creation_date: 2015-01-19T15:03:16Z + +[Term] +id: GO:1903820 +name: signal transduction involved in mitotic cytokinesis checkpoint +namespace: biological_process +def: "Any signal transduction that is involved in a mitotic cytokinesis checkpoint." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "signaling cascade involved in mitotic cytokinesis checkpoint" NARROW [GOC:TermGenie] +synonym: "signaling pathway involved in mitotic cytokinesis checkpoint" RELATED [GOC:TermGenie] +synonym: "signalling cascade involved in mitotic cytokinesis checkpoint" NARROW [GOC:TermGenie] +synonym: "signalling pathway involved in mitotic cytokinesis checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072398 ! signal transduction involved in cytokinesis checkpoint +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0044878 ! mitotic cytokinesis checkpoint +relationship: part_of GO:0044878 ! mitotic cytokinesis checkpoint +created_by: jl +creation_date: 2015-01-19T15:03:50Z + +[Term] +id: GO:1903821 +name: detection of stimulus involved in morphogenesis checkpoint +namespace: biological_process +def: "Any detection of stimulus that is involved in morphogenesis checkpoint." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "detection of stimulus involved in septin checkpoint" RELATED [GOC:TermGenie] +synonym: "perception of stimulus involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "perception of stimulus involved in septin checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus detection involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus detection involved in septin checkpoint" RELATED [GOC:TermGenie] +synonym: "stimulus sensing involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "stimulus sensing involved in septin checkpoint" RELATED [GOC:TermGenie] +is_a: GO:0072412 ! detection of stimulus involved in mitotic cell cycle checkpoint +intersection_of: GO:0051606 ! detection of stimulus +intersection_of: part_of GO:0044879 ! morphogenesis checkpoint +relationship: part_of GO:0044879 ! morphogenesis checkpoint +created_by: jl +creation_date: 2015-01-19T15:03:59Z + +[Term] +id: GO:1903822 +name: signal transduction involved in morphogenesis checkpoint +namespace: biological_process +def: "Any signal transduction that is involved in morphogenesis checkpoint." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] +synonym: "signal transduction involved in septin checkpoint" EXACT [GOC:TermGenie] +synonym: "signaling cascade involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "signaling cascade involved in septin checkpoint" EXACT [GOC:TermGenie] +synonym: "signaling pathway involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "signaling pathway involved in septin checkpoint" EXACT [GOC:TermGenie] +synonym: "signalling cascade involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "signalling cascade involved in septin checkpoint" EXACT [GOC:TermGenie] +synonym: "signalling pathway involved in morphogenesis checkpoint" EXACT [GOC:TermGenie] +synonym: "signalling pathway involved in septin checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0007165 ! signal transduction +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0044879 ! morphogenesis checkpoint +relationship: part_of GO:0044879 ! morphogenesis checkpoint +created_by: jl +creation_date: 2015-01-19T15:04:08Z + +[Term] +id: GO:1903823 +name: telomere single strand break repair +namespace: biological_process +def: "Single strand break repair that takes place in a telomere." [GO_REF:0000062, GOC:TermGenie, PMID:24374808] +synonym: "single strand break repair in telomere" EXACT [GOC:TermGenie] +synonym: "telomere single-strand break repair" EXACT [] +synonym: "telomere SSBR" RELATED [] +synonym: "telomeric single strand break repair" EXACT [] +is_a: GO:0000012 ! single strand break repair +intersection_of: GO:0000012 ! single strand break repair +intersection_of: occurs_in GO:0000781 ! chromosome, telomeric region +relationship: occurs_in GO:0000781 ! chromosome, telomeric region +created_by: jl +creation_date: 2015-01-19T16:12:29Z + +[Term] +id: GO:1903824 +name: negative regulation of telomere single strand break repair +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair." [GO_REF:0000058, GOC:TermGenie, PMID:24374808] +synonym: "down regulation of single strand break repair in telomere" EXACT [GOC:TermGenie] +synonym: "down regulation of telomere single strand break repair" EXACT [GOC:TermGenie] +synonym: "down regulation of telomere single-strand break repair" EXACT [GOC:TermGenie] +synonym: "down regulation of telomere SSBR" RELATED [GOC:TermGenie] +synonym: "down regulation of telomeric single strand break repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of single strand break repair in telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere single strand break repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere single-strand break repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere SSBR" RELATED [GOC:TermGenie] +synonym: "down-regulation of telomeric single strand break repair" EXACT [GOC:TermGenie] +synonym: "downregulation of single strand break repair in telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere single strand break repair" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere single-strand break repair" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere SSBR" RELATED [GOC:TermGenie] +synonym: "downregulation of telomeric single strand break repair" EXACT [GOC:TermGenie] +synonym: "inhibition of single strand break repair in telomere" NARROW [GOC:TermGenie] +synonym: "inhibition of telomere single strand break repair" NARROW [GOC:TermGenie] +synonym: "inhibition of telomere single-strand break repair" NARROW [GOC:TermGenie] +synonym: "inhibition of telomere SSBR" RELATED [GOC:TermGenie] +synonym: "inhibition of telomeric single strand break repair" NARROW [GOC:TermGenie] +synonym: "negative regulation of single strand break repair in telomere" EXACT [GOC:TermGenie] +synonym: "negative regulation of telomere single-strand break repair" EXACT [GOC:TermGenie] +synonym: "negative regulation of telomere SSBR" RELATED [GOC:TermGenie] +synonym: "negative regulation of telomeric single strand break repair" EXACT [GOC:TermGenie] +is_a: GO:1903517 ! negative regulation of single strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903823 ! telomere single strand break repair +relationship: negatively_regulates GO:1903823 ! telomere single strand break repair +created_by: jl +creation_date: 2015-01-19T16:24:37Z + +[Term] +id: GO:1903825 +name: organic acid transmembrane transport +namespace: biological_process +def: "The process in which an organic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] +is_a: GO:0015849 ! organic acid transport +is_a: GO:0055085 ! transmembrane transport +created_by: vw +creation_date: 2015-01-20T10:20:58Z + +[Term] +id: GO:1903826 +name: arginine transmembrane transport +namespace: biological_process +def: "The directed movement of arginine across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:18357653] +is_a: GO:0015809 ! arginine transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1990822 ! basic amino acid transmembrane transport +created_by: vw +creation_date: 2015-01-20T10:38:15Z + +[Term] +id: GO:1903827 +name: regulation of cellular protein localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "regulation of channel localizer activity" NARROW [GOC:TermGenie] +is_a: GO:0032880 ! regulation of protein localization +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034613 ! cellular protein localization +relationship: regulates GO:0034613 ! cellular protein localization +created_by: jl +creation_date: 2015-01-20T14:32:14Z + +[Term] +id: GO:1903828 +name: negative regulation of cellular protein localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "down regulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "downregulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein localisation" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein localization" NARROW [GOC:TermGenie] +synonym: "inhibition of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of channel localizer activity" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034613 ! cellular protein localization +relationship: negatively_regulates GO:0034613 ! cellular protein localization +created_by: jl +creation_date: 2015-01-20T14:32:24Z + +[Term] +id: GO:1903829 +name: positive regulation of cellular protein localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of cellular protein localisation" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein localization" NARROW [GOC:TermGenie] +synonym: "activation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "up regulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of channel localizer activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie] +synonym: "upregulation of channel localizer activity" NARROW [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034613 ! cellular protein localization +relationship: positively_regulates GO:0034613 ! cellular protein localization +created_by: jl +creation_date: 2015-01-20T14:32:33Z + +[Term] +id: GO:1903830 +name: magnesium ion transmembrane transport +namespace: biological_process +def: "The directed movement of magnesium ion across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:11254124] +is_a: GO:0015693 ! magnesium ion transport +is_a: GO:0098662 ! inorganic cation transmembrane transport +created_by: mcc +creation_date: 2015-01-21T17:38:30Z + +[Term] +id: GO:1903831 +name: signal transduction involved in cellular response to ammonium ion +namespace: biological_process +def: "Any signal transduction that is involved in cellular response to ammonium ion." [GO_REF:0000060, GOC:TermGenie, PMID:16297994] +synonym: "signaling cascade involved in cellular response to ammonium ion" NARROW [GOC:TermGenie] +synonym: "signaling pathway involved in cellular response to ammonium ion" RELATED [GOC:TermGenie] +synonym: "signalling cascade involved in cellular response to ammonium ion" NARROW [GOC:TermGenie] +synonym: "signalling pathway involved in cellular response to ammonium ion" RELATED [GOC:TermGenie] +is_a: GO:0007165 ! signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: part_of GO:0071242 ! cellular response to ammonium ion +relationship: part_of GO:0071242 ! cellular response to ammonium ion +created_by: al +creation_date: 2015-01-21T17:52:09Z + +[Term] +id: GO:1903832 +name: regulation of cellular response to amino acid starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation." [GO_REF:0000058, GOC:TermGenie, PMID:25002487, PMID:7623840] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034198 ! cellular response to amino acid starvation +relationship: regulates GO:0034198 ! cellular response to amino acid starvation +created_by: rn +creation_date: 2015-01-21T18:44:28Z + +[Term] +id: GO:1903833 +name: positive regulation of cellular response to amino acid starvation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation." [GO_REF:0000058, GOC:TermGenie, PMID:25002487, PMID:7623840] +synonym: "activation of cellular response to amino acid starvation" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to amino acid starvation" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0032109 ! positive regulation of response to nutrient levels +is_a: GO:1903832 ! regulation of cellular response to amino acid starvation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034198 ! cellular response to amino acid starvation +relationship: positively_regulates GO:0034198 ! cellular response to amino acid starvation +created_by: rn +creation_date: 2015-01-21T18:44:37Z + +[Term] +id: GO:1903837 +name: regulation of mRNA 3'-UTR binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:19575011] +synonym: "regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +is_a: GO:1902415 ! regulation of mRNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003730 ! mRNA 3'-UTR binding +relationship: regulates GO:0003730 ! mRNA 3'-UTR binding +created_by: als +creation_date: 2015-01-22T11:53:59Z + +[Term] +id: GO:1903838 +name: negative regulation of mRNA 3'-UTR binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:19575011] +synonym: "down regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +synonym: "inhibition of mRNA 3' UTR binding" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA 3'-UTR binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +is_a: GO:1903837 ! regulation of mRNA 3'-UTR binding +is_a: GO:1904572 ! negative regulation of mRNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003730 ! mRNA 3'-UTR binding +relationship: negatively_regulates GO:0003730 ! mRNA 3'-UTR binding +created_by: als +creation_date: 2015-01-22T11:54:08Z + +[Term] +id: GO:1903839 +name: positive regulation of mRNA 3'-UTR binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:19575011] +synonym: "activation of mRNA 3' UTR binding" NARROW [GOC:TermGenie] +synonym: "activation of mRNA 3'-UTR binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA 3' UTR binding" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA 3'-UTR binding" EXACT [GOC:TermGenie] +is_a: GO:1902416 ! positive regulation of mRNA binding +is_a: GO:1903837 ! regulation of mRNA 3'-UTR binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003730 ! mRNA 3'-UTR binding +relationship: positively_regulates GO:0003730 ! mRNA 3'-UTR binding +created_by: als +creation_date: 2015-01-22T11:54:17Z + +[Term] +id: GO:1903840 +name: response to arsenite(3-) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:12106899] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:1903842 ! response to arsenite ion +created_by: mr +creation_date: 2015-01-22T19:49:25Z + +[Term] +id: GO:1903841 +name: cellular response to arsenite(3-) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:12106899] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:1903840 ! response to arsenite(3-) +is_a: GO:1903843 ! cellular response to arsenite ion +created_by: mr +creation_date: 2015-01-22T19:49:35Z + +[Term] +id: GO:1903842 +name: response to arsenite ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:12106899] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0046685 ! response to arsenic-containing substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mr +creation_date: 2015-01-22T19:56:05Z + +[Term] +id: GO:1903843 +name: cellular response to arsenite ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:12106899] +is_a: GO:0071243 ! cellular response to arsenic-containing substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1903842 ! response to arsenite ion +created_by: mr +creation_date: 2015-01-22T19:56:14Z + +[Term] +id: GO:1903844 +name: regulation of cellular response to transforming growth factor beta stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +relationship: regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +created_by: rph +creation_date: 2015-01-23T11:25:11Z + +[Term] +id: GO:1903845 +name: negative regulation of cellular response to transforming growth factor beta stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "down regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to TGF-beta stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to TGFbeta stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to transforming growth factor beta stimulus" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:1903844 ! regulation of cellular response to transforming growth factor beta stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +relationship: negatively_regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +created_by: rph +creation_date: 2015-01-23T11:25:21Z + +[Term] +id: GO:1903846 +name: positive regulation of cellular response to transforming growth factor beta stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "activation of cellular response to TGF-beta stimulus" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to TGFbeta stimulus" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to transforming growth factor beta stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to TGF-beta stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to TGFbeta stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to transforming growth factor beta stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1903844 ! regulation of cellular response to transforming growth factor beta stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +relationship: positively_regulates GO:0071560 ! cellular response to transforming growth factor beta stimulus +created_by: rph +creation_date: 2015-01-23T11:25:30Z + +[Term] +id: GO:1903847 +name: regulation of aorta morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +is_a: GO:1905651 ! regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035909 ! aorta morphogenesis +relationship: regulates GO:0035909 ! aorta morphogenesis +created_by: rph +creation_date: 2015-01-23T14:00:51Z + +[Term] +id: GO:1903848 +name: negative regulation of aorta morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of aorta morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:1903847 ! regulation of aorta morphogenesis +is_a: GO:1905652 ! negative regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035909 ! aorta morphogenesis +relationship: negatively_regulates GO:0035909 ! aorta morphogenesis +created_by: rph +creation_date: 2015-01-23T14:01:01Z + +[Term] +id: GO:1903849 +name: positive regulation of aorta morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] +synonym: "activation of aorta morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:1903847 ! regulation of aorta morphogenesis +is_a: GO:1905653 ! positive regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035909 ! aorta morphogenesis +relationship: positively_regulates GO:0035909 ! aorta morphogenesis +created_by: rph +creation_date: 2015-01-23T14:01:09Z + +[Term] +id: GO:1903850 +name: regulation of cristae formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cristae formation." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:19279012] +comment: AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype +is_a: GO:0010821 ! regulation of mitochondrion organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042407 ! cristae formation +relationship: regulates GO:0042407 ! cristae formation +created_by: pad +creation_date: 2015-01-27T09:42:23Z + +[Term] +id: GO:1903851 +name: negative regulation of cristae formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:19279012] +comment: AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype +synonym: "down regulation of cristae formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cristae formation" EXACT [GOC:TermGenie] +synonym: "downregulation of cristae formation" EXACT [GOC:TermGenie] +synonym: "inhibition of cristae formation" NARROW [GOC:TermGenie] +is_a: GO:0010823 ! negative regulation of mitochondrion organization +is_a: GO:1903850 ! regulation of cristae formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042407 ! cristae formation +relationship: negatively_regulates GO:0042407 ! cristae formation +created_by: pad +creation_date: 2015-01-27T09:42:33Z + +[Term] +id: GO:1903852 +name: positive regulation of cristae formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cristae formation." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:19279012] +comment: AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype +synonym: "activation of cristae formation" NARROW [GOC:TermGenie] +synonym: "up regulation of cristae formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cristae formation" EXACT [GOC:TermGenie] +synonym: "upregulation of cristae formation" EXACT [GOC:TermGenie] +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:1903850 ! regulation of cristae formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042407 ! cristae formation +relationship: positively_regulates GO:0042407 ! cristae formation +created_by: pad +creation_date: 2015-01-27T09:42:42Z + +[Term] +id: GO:1903853 +name: regulation of stress response to copper ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stress response to copper ion." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23437011] +synonym: "regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "regulation of stress response to copper" BROAD [GOC:TermGenie] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990169 ! stress response to copper ion +relationship: regulates GO:1990169 ! stress response to copper ion +created_by: kmv +creation_date: 2015-01-29T20:15:23Z + +[Term] +id: GO:1903854 +name: negative regulation of stress response to copper ion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23437011] +synonym: "down regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "down regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "down regulation of stress response to copper ion" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "down-regulation of stress response to copper ion" EXACT [GOC:TermGenie] +synonym: "downregulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "downregulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "downregulation of stress response to copper ion" EXACT [GOC:TermGenie] +synonym: "inhibition of response to copper ion stress" NARROW [GOC:TermGenie] +synonym: "inhibition of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "inhibition of stress response to copper ion" NARROW [GOC:TermGenie] +synonym: "negative regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to copper toxicity" RELATED [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1903853 ! regulation of stress response to copper ion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990169 ! stress response to copper ion +relationship: negatively_regulates GO:1990169 ! stress response to copper ion +created_by: kmv +creation_date: 2015-01-29T20:15:33Z + +[Term] +id: GO:1903855 +name: positive regulation of stress response to copper ion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stress response to copper ion." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:23437011] +synonym: "activation of response to copper ion stress" NARROW [GOC:TermGenie] +synonym: "activation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "activation of stress response to copper ion" NARROW [GOC:TermGenie] +synonym: "positive regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "up regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "up regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "up regulation of stress response to copper ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "up-regulation of stress response to copper ion" EXACT [GOC:TermGenie] +synonym: "upregulation of response to copper ion stress" EXACT [GOC:TermGenie] +synonym: "upregulation of response to copper toxicity" RELATED [GOC:TermGenie] +synonym: "upregulation of stress response to copper ion" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1903853 ! regulation of stress response to copper ion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990169 ! stress response to copper ion +relationship: positively_regulates GO:1990169 ! stress response to copper ion +created_by: kmv +creation_date: 2015-01-29T20:15:42Z + +[Term] +id: GO:1903856 +name: regulation of cytokinin dehydrogenase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity." [GO_REF:0000059, GOC:TermGenie, PMID:25535363] +synonym: "regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019139 ! cytokinin dehydrogenase activity +relationship: regulates GO:0019139 ! cytokinin dehydrogenase activity +created_by: tb +creation_date: 2015-01-30T00:33:51Z + +[Term] +id: GO:1903857 +name: negative regulation of cytokinin dehydrogenase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity." [GO_REF:0000059, GOC:TermGenie, PMID:25535363] +synonym: "down regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytokinin dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinin dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinin dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytokinin dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of N6-dimethylallyladenine:acceptor oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytokinin oxidase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1903856 ! regulation of cytokinin dehydrogenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019139 ! cytokinin dehydrogenase activity +relationship: negatively_regulates GO:0019139 ! cytokinin dehydrogenase activity +created_by: tb +creation_date: 2015-01-30T00:34:01Z + +[Term] +id: GO:1903858 +name: protein localization to old growing cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an old growing cell tip." [GO_REF:0000087, GOC:TermGenie, PMID:17895368] +synonym: "protein localisation in old growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to old growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization in old growing cell tip" EXACT [GOC:TermGenie] +is_a: GO:1902486 ! protein localization to growing cell tip +created_by: mah +creation_date: 2015-02-02T13:53:29Z + +[Term] +id: GO:1903859 +name: regulation of dendrite extension +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendrite extension." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24898855] +comment: An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype. +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0010975 ! regulation of neuron projection development +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:0048638 ! regulation of developmental growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097484 ! dendrite extension +relationship: regulates GO:0097484 ! dendrite extension +created_by: pad +creation_date: 2015-02-02T15:33:51Z + +[Term] +id: GO:1903860 +name: negative regulation of dendrite extension +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24898855] +comment: An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype. +synonym: "down regulation of dendrite extension" EXACT [GOC:TermGenie] +synonym: "down-regulation of dendrite extension" EXACT [GOC:TermGenie] +synonym: "downregulation of dendrite extension" EXACT [GOC:TermGenie] +synonym: "inhibition of dendrite extension" NARROW [GOC:TermGenie] +synonym: "up regulation of dendrite retraction" EXACT [GOC:pad] +synonym: "up-regulation of dendrite retraction" EXACT [GOC:pad] +is_a: GO:0010977 ! negative regulation of neuron projection development +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1903859 ! regulation of dendrite extension +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097484 ! dendrite extension +relationship: negatively_regulates GO:0097484 ! dendrite extension +created_by: pad +creation_date: 2015-02-02T15:34:00Z + +[Term] +id: GO:1903861 +name: positive regulation of dendrite extension +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendrite extension." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24898855] +comment: An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype. +synonym: "activation of dendrite extension" NARROW [GOC:TermGenie] +synonym: "up regulation of dendrite extension" EXACT [GOC:TermGenie] +synonym: "up-regulation of dendrite extension" EXACT [GOC:TermGenie] +synonym: "upregulation of dendrite extension" EXACT [GOC:TermGenie] +is_a: GO:0010976 ! positive regulation of neuron projection development +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1903859 ! regulation of dendrite extension +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097484 ! dendrite extension +relationship: positively_regulates GO:0097484 ! dendrite extension +created_by: pad +creation_date: 2015-02-02T15:34:09Z + +[Term] +id: GO:1903862 +name: positive regulation of oxidative phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:10225962] +synonym: "activation of oxidative phosphorylation" NARROW [GOC:TermGenie] +synonym: "activation of respiratory-chain phosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of respiratory-chain phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of oxidative phosphorylation" EXACT [GOC:TermGenie] +synonym: "up regulation of respiratory-chain phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of oxidative phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of respiratory-chain phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of oxidative phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of respiratory-chain phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0002082 ! regulation of oxidative phosphorylation +is_a: GO:0042327 ! positive regulation of phosphorylation +is_a: GO:1903580 ! positive regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006119 ! oxidative phosphorylation +relationship: positively_regulates GO:0006119 ! oxidative phosphorylation +created_by: sl +creation_date: 2015-02-02T23:40:22Z + +[Term] +id: GO:1903863 +name: P granule assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a P granule." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, PMID:25535836] +synonym: "germline granule assembly" EXACT [GOC:TermGenie] +synonym: "germline granule formation" EXACT [GOC:TermGenie] +synonym: "P granule formation" EXACT [GOC:TermGenie] +synonym: "polar granule assembly" EXACT [GOC:TermGenie] +synonym: "polar granule formation" EXACT [GOC:TermGenie] +is_a: GO:0030719 ! P granule organization +is_a: GO:0070925 ! organelle assembly +created_by: kmv +creation_date: 2015-02-04T15:27:02Z + +[Term] +id: GO:1903864 +name: P granule disassembly +namespace: biological_process +def: "The disaggregation of a P granule into its constituent components." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, PMID:25535836] +synonym: "germline granule disassembly" EXACT [GOC:TermGenie] +synonym: "polar granule disassembly" EXACT [GOC:TermGenie] +is_a: GO:0030719 ! P granule organization +is_a: GO:1903008 ! organelle disassembly +created_by: kmv +creation_date: 2015-02-04T15:27:12Z + +[Term] +id: GO:1903865 +name: sigma factor antagonist complex +namespace: cellular_component +def: "A protein complex which is capable of sigma factor antagonist activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:23687042] +is_a: GO:0005667 ! transcription regulator complex +created_by: bhm +creation_date: 2015-02-04T15:39:34Z + +[Term] +id: GO:1903866 +name: palisade mesophyll development +namespace: biological_process +def: "The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure." [GO_REF:0000080, GOC:TermGenie, PMID:24663344] +synonym: "palisade parenchyma development" RELATED [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: tb +creation_date: 2015-02-04T21:51:44Z + +[Term] +id: GO:1903867 +name: extraembryonic membrane development +namespace: biological_process +def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584] +is_a: GO:0048856 ! anatomical structure development +created_by: cjm +creation_date: 2015-02-05T00:42:16Z + +[Term] +id: GO:1903868 +name: regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity." [GO_REF:0000059, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:24769206] +synonym: "regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolate reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydrofolic acid reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of MetF" RELATED [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolate reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of methylenetetrahydrofolic acid reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of MTHFR activity" BROAD [GOC:TermGenie] +synonym: "regulation of N(5),N(10)-methylenetetrahydrofolate reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of N(5,10)-methylenetetrahydrofolate reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +relationship: regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +created_by: rph +creation_date: 2015-02-05T13:26:14Z + +[Term] +id: GO:1903869 +name: negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity." [GO_REF:0000059, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:24769206] +synonym: "down regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "down regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of MetF" RELATED [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "down regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "down regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of MetF" RELATED [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "down-regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "downregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of MetF" RELATED [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "downregulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "downregulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 5,10-CH(2)-H(4)folate reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5,10-CH2-H4folate reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "inhibition of 5,10-methylenetetrahydrofolate reductase (FADH) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of MetF" RELATED [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate reductase (NAD(P)H) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate reductase (NADPH(2)) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate reductase (NADPH2)" NARROW [GOC:TermGenie] +synonym: "inhibition of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "inhibition of N5,10-methylenetetrahydrofolate reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of N5,N10-methylenetetrahydrofolate reductase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of MetF" RELATED [GOC:TermGenie] +synonym: "negative regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "negative regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1903868 ! regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +relationship: negatively_regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +created_by: rph +creation_date: 2015-02-05T13:26:25Z + +[Term] +id: GO:1903870 +name: positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity." [GO_REF:0000059, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:24769206] +synonym: "activation of 5,10-CH(2)-H(4)folate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5,10-CH2-H4folate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "activation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" NARROW [GOC:TermGenie] +synonym: "activation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" NARROW [GOC:TermGenie] +synonym: "activation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" NARROW [GOC:TermGenie] +synonym: "activation of 5,10-methylenetetrahydropteroylglutamate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of MetF" RELATED [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate reductase (NAD(P)H) activity" NARROW [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate reductase (NADPH(2)) activity" NARROW [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate reductase (NADPH2)" NARROW [GOC:TermGenie] +synonym: "activation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "activation of N5,10-methylenetetrahydrofolate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of N5,N10-methylenetetrahydrofolate reductase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of MetF" RELATED [GOC:TermGenie] +synonym: "positive regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "positive regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "up regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of MetF" RELATED [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "up regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "up regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of MetF" RELATED [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "up-regulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-CH(2)-H(4)folate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-CH2-H4folate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [GOC:TermGenie] +synonym: "upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of MetF" RELATED [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate reductase (NADPH2)" EXACT [GOC:TermGenie] +synonym: "upregulation of methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [GOC:TermGenie] +synonym: "upregulation of N5,10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of N5,N10-methylenetetrahydrofolate reductase activity" EXACT [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1903868 ! regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +relationship: positively_regulates GO:0004489 ! methylenetetrahydrofolate reductase (NAD(P)H) activity +created_by: rph +creation_date: 2015-02-05T13:26:33Z + +[Term] +id: GO:1903871 +name: DNA recombinase mediator complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex." [GO_REF:0000079, GOC:rb, GOC:TermGenie, PMID:18347097] +synonym: "DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +is_a: GO:0090735 ! DNA repair complex assembly +created_by: rb +creation_date: 2015-02-05T23:05:10Z + +[Term] +id: GO:1903872 +name: regulation of DNA recombinase mediator complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly." [GO_REF:0000058, GOC:rb, GOC:TermGenie, PMID:18347097] +synonym: "regulation of DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903871 ! DNA recombinase mediator complex assembly +relationship: regulates GO:1903871 ! DNA recombinase mediator complex assembly +created_by: rb +creation_date: 2015-02-05T23:36:45Z + +[Term] +id: GO:1903873 +name: negative regulation of DNA recombinase mediator complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly." [GO_REF:0000058, GOC:rb, GOC:TermGenie, PMID:18347097] +synonym: "down regulation of DNA recombinase mediator complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA recombinase mediator complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA recombinase mediator complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA recombinase mediator complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA recombinase mediator complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA recombinase mediator complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1903872 ! regulation of DNA recombinase mediator complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903871 ! DNA recombinase mediator complex assembly +relationship: negatively_regulates GO:1903871 ! DNA recombinase mediator complex assembly +created_by: rb +creation_date: 2015-02-05T23:36:54Z + +[Term] +id: GO:1903875 +name: corticosterone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with corticosterone." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10802282] +is_a: GO:0043178 ! alcohol binding +is_a: GO:1990239 ! steroid hormone binding +created_by: mr +creation_date: 2015-02-06T16:02:35Z + +[Term] +id: GO:1903876 +name: 11-deoxycortisol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 11-deoxycortisol." [GO_REF:0000067, GOC:TermGenie, PMID:10802282] +is_a: GO:0043178 ! alcohol binding +is_a: GO:1990239 ! steroid hormone binding +created_by: mr +creation_date: 2015-02-06T16:02:44Z + +[Term] +id: GO:1903877 +name: 21-deoxycortisol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 21-deoxycortisol." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10802282] +is_a: GO:0005496 ! steroid binding +created_by: mr +creation_date: 2015-02-06T16:02:54Z + +[Term] +id: GO:1903878 +name: 11-deoxycorticosterone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 11-deoxycorticosterone." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10802282] +is_a: GO:0043178 ! alcohol binding +is_a: GO:1990239 ! steroid hormone binding +created_by: mr +creation_date: 2015-02-06T16:03:03Z + +[Term] +id: GO:1903879 +name: 11beta-hydroxyprogesterone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 11beta-hydroxyprogesterone." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10802282] +is_a: GO:0005496 ! steroid binding +created_by: mr +creation_date: 2015-02-06T16:03:12Z + +[Term] +id: GO:1903880 +name: 17alpha-hydroxyprogesterone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 17alpha-hydroxyprogesterone." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10802282] +is_a: GO:0005496 ! steroid binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0043178 ! alcohol binding +created_by: mr +creation_date: 2015-02-06T16:03:22Z + +[Term] +id: GO:1903881 +name: regulation of interleukin-17-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097400 ! interleukin-17-mediated signaling pathway +relationship: regulates GO:0097400 ! interleukin-17-mediated signaling pathway +created_by: krc +creation_date: 2015-02-06T16:26:38Z + +[Term] +id: GO:1903882 +name: negative regulation of interleukin-17-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "down regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of IL-17-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of IL-17-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-17-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-17-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:1903881 ! regulation of interleukin-17-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097400 ! interleukin-17-mediated signaling pathway +relationship: negatively_regulates GO:0097400 ! interleukin-17-mediated signaling pathway +created_by: krc +creation_date: 2015-02-06T16:26:47Z + +[Term] +id: GO:1903883 +name: positive regulation of interleukin-17-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "activation of IL-17-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of IL-17-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-17-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-17-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-17-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-17-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-17-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:1903881 ! regulation of interleukin-17-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097400 ! interleukin-17-mediated signaling pathway +relationship: positively_regulates GO:0097400 ! interleukin-17-mediated signaling pathway +created_by: krc +creation_date: 2015-02-06T16:26:56Z + +[Term] +id: GO:1903884 +name: regulation of chemokine (C-C motif) ligand 20 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "regulation of CCL20 production" EXACT [GOC:TermGenie] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +relationship: regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +created_by: krc +creation_date: 2015-02-06T16:31:02Z + +[Term] +id: GO:1903885 +name: negative regulation of chemokine (C-C motif) ligand 20 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "down regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "down regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "down regulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "down regulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +synonym: "down-regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "down-regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "down-regulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +synonym: "downregulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "downregulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "downregulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "downregulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +synonym: "inhibition of C-C motif chemokine 20 production" NARROW [GOC:TermGenie] +synonym: "inhibition of CCL-20 production" NARROW [GOC:TermGenie] +synonym: "inhibition of CCL20 production" NARROW [GOC:TermGenie] +synonym: "inhibition of chemokine (C-C motif) ligand 20 production" NARROW [GOC:TermGenie] +synonym: "negative regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "negative regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "negative regulation of CCL20 production" EXACT [GOC:TermGenie] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:1903884 ! regulation of chemokine (C-C motif) ligand 20 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +relationship: negatively_regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +created_by: krc +creation_date: 2015-02-06T16:31:11Z + +[Term] +id: GO:1903886 +name: positive regulation of chemokine (C-C motif) ligand 20 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:20054338] +synonym: "activation of C-C motif chemokine 20 production" NARROW [GOC:TermGenie] +synonym: "activation of CCL-20 production" NARROW [GOC:TermGenie] +synonym: "activation of CCL20 production" NARROW [GOC:TermGenie] +synonym: "activation of chemokine (C-C motif) ligand 20 production" NARROW [GOC:TermGenie] +synonym: "positive regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "positive regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "positive regulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "up regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "up regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "up regulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "up regulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +synonym: "up-regulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "up-regulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "up-regulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +synonym: "upregulation of C-C motif chemokine 20 production" EXACT [GOC:TermGenie] +synonym: "upregulation of CCL-20 production" EXACT [GOC:TermGenie] +synonym: "upregulation of CCL20 production" EXACT [GOC:TermGenie] +synonym: "upregulation of chemokine (C-C motif) ligand 20 production" EXACT [GOC:TermGenie] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:1903884 ! regulation of chemokine (C-C motif) ligand 20 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +relationship: positively_regulates GO:0036392 ! chemokine (C-C motif) ligand 20 production +created_by: krc +creation_date: 2015-02-06T16:31:20Z + +[Term] +id: GO:1903888 +name: regulation of plant epidermal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:123345] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090627 ! plant epidermal cell differentiation +relationship: regulates GO:0090627 ! plant epidermal cell differentiation +created_by: tb +creation_date: 2015-02-06T22:29:38Z + +[Term] +id: GO:1903889 +name: negative regulation of plant epidermal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:123345] +synonym: "down regulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of plant epidermal cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1903888 ! regulation of plant epidermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090627 ! plant epidermal cell differentiation +relationship: negatively_regulates GO:0090627 ! plant epidermal cell differentiation +created_by: tb +creation_date: 2015-02-06T22:29:52Z + +[Term] +id: GO:1903890 +name: positive regulation of plant epidermal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:123345] +synonym: "activation of plant epidermal cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of plant epidermal cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1903888 ! regulation of plant epidermal cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090627 ! plant epidermal cell differentiation +relationship: positively_regulates GO:0090627 ! plant epidermal cell differentiation +created_by: tb +creation_date: 2015-02-06T22:30:02Z + +[Term] +id: GO:1903891 +name: regulation of ATF6-mediated unfolded protein response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "regulation of ATF6 signal transduction pathway" BROAD [GOC:TermGenie] +synonym: "regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036500 ! ATF6-mediated unfolded protein response +relationship: regulates GO:0036500 ! ATF6-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:17:15Z + +[Term] +id: GO:1903892 +name: negative regulation of ATF6-mediated unfolded protein response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "down regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "down regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "down regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "down regulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "down-regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down-regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "downregulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "downregulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "downregulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "downregulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "downregulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "inhibition of activating transcription factor 6 signaling in unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of ATF6 branch of UPR" NARROW [GOC:TermGenie] +synonym: "inhibition of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "inhibition of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "inhibition of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "inhibition of ATF6-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of UPR signaling by ATF6 stress sensor" NARROW [GOC:TermGenie] +synonym: "negative regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "negative regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900102 ! negative regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903891 ! regulation of ATF6-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036500 ! ATF6-mediated unfolded protein response +relationship: negatively_regulates GO:0036500 ! ATF6-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:17:26Z + +[Term] +id: GO:1903893 +name: positive regulation of ATF6-mediated unfolded protein response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "activation of activating transcription factor 6 signaling in unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of ATF6 branch of UPR" NARROW [GOC:TermGenie] +synonym: "activation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "activation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "activation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "activation of ATF6-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum unfolded protein response; ATF6 signaling" NARROW [GOC:TermGenie] +synonym: "activation of UPR signaling by ATF6 stress sensor" NARROW [GOC:TermGenie] +synonym: "positive regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "up regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "up regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "up regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "up regulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "up-regulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up-regulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +synonym: "upregulation of activating transcription factor 6 signaling in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of ATF6 branch of UPR" EXACT [GOC:TermGenie] +synonym: "upregulation of ATF6 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "upregulation of ATF6-alpha UPR branch" NARROW [GOC:TermGenie] +synonym: "upregulation of ATF6-beta UPR branch" NARROW [GOC:TermGenie] +synonym: "upregulation of ATF6-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of UPR signaling by ATF6 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900103 ! positive regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903891 ! regulation of ATF6-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036500 ! ATF6-mediated unfolded protein response +relationship: positively_regulates GO:0036500 ! ATF6-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:17:36Z + +[Term] +id: GO:1903894 +name: regulation of IRE1-mediated unfolded protein response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "regulation of ERN1-mediated unfolded protein response" RELATED [HGNC:3449] +synonym: "regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "regulation of IRE1 signal transduction pathway" BROAD [GOC:TermGenie] +synonym: "regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036498 ! IRE1-mediated unfolded protein response +relationship: regulates GO:0036498 ! IRE1-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:17:46Z + +[Term] +id: GO:1903895 +name: negative regulation of IRE1-mediated unfolded protein response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "down regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "down regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down regulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "down regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "down regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "down-regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "down-regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down-regulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "down-regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "down-regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "downregulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "downregulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "downregulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "downregulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "downregulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "inhibition of IRE1 branch of UPR" NARROW [GOC:TermGenie] +synonym: "inhibition of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "inhibition of IRE1-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of UPR signaling by IRE1 stress sensor" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of ERN1-mediated unfolded protein response" RELATED [HGNC:3449] +synonym: "negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "negative regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "negative regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "negative regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "negative regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "negative regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900102 ! negative regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903894 ! regulation of IRE1-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036498 ! IRE1-mediated unfolded protein response +relationship: negatively_regulates GO:0036498 ! IRE1-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:17:55Z + +[Term] +id: GO:1903896 +name: positive regulation of IRE1-mediated unfolded protein response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "activation of endoplasmic reticulum unfolded protein response; IRE1 signaling" NARROW [GOC:TermGenie] +synonym: "activation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "activation of IRE1 branch of UPR" NARROW [GOC:TermGenie] +synonym: "activation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "activation of IRE1-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of UPR signaling by IRE1 stress sensor" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of ERN1-mediated unfolded protein response" RELATED [HGNC:3449] +synonym: "positive regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "positive regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "positive regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "positive regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "positive regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "up regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "up regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up regulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "up regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "up regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "up-regulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "up-regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up-regulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "up-regulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "up-regulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED [GOC:TermGenie] +synonym: "upregulation of IRE1 branch of UPR" EXACT [GOC:TermGenie] +synonym: "upregulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "upregulation of IRE1-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of IRE1alpha unfolded protein response" NARROW [GOC:TermGenie] +synonym: "upregulation of IRE1p unfolded protein response" NARROW [GOC:TermGenie] +synonym: "upregulation of UPR signaling by IRE1 stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900103 ! positive regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903894 ! regulation of IRE1-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036498 ! IRE1-mediated unfolded protein response +relationship: positively_regulates GO:0036498 ! IRE1-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:18:04Z + +[Term] +id: GO:1903897 +name: regulation of PERK-mediated unfolded protein response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "regulation of EIF2AK3-mediated unfolded protein response" RELATED [HGNC:3255] +synonym: "regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "regulation of PERK signal transduction pathway" BROAD [GOC:TermGenie] +synonym: "regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036499 ! PERK-mediated unfolded protein response +relationship: regulates GO:0036499 ! PERK-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:18:14Z + +[Term] +id: GO:1903898 +name: negative regulation of PERK-mediated unfolded protein response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "down regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "down regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "down regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down regulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "down-regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "down-regulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "downregulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "downregulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum unfolded protein response; PERK signaling" NARROW [GOC:TermGenie] +synonym: "inhibition of PERK branch of UPR" NARROW [GOC:TermGenie] +synonym: "inhibition of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "inhibition of PERK-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of PKR-like ER kinase signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of UPR signaling by PERK stress sensor" NARROW [GOC:TermGenie] +synonym: "negative regulation of EIF2AK3-mediated unfolded protein response" RELATED [HGNC:3255] +synonym: "negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "negative regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900102 ! negative regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903897 ! regulation of PERK-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036499 ! PERK-mediated unfolded protein response +relationship: negatively_regulates GO:0036499 ! PERK-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:18:23Z + +[Term] +id: GO:1903899 +name: positive regulation of PERK-mediated unfolded protein response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210] +synonym: "activation of endoplasmic reticulum unfolded protein response; PERK signaling" NARROW [GOC:TermGenie] +synonym: "activation of PERK branch of UPR" NARROW [GOC:TermGenie] +synonym: "activation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "activation of PERK-mediated unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of PKR-like ER kinase signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of UPR signaling by PERK stress sensor" NARROW [GOC:TermGenie] +synonym: "positive regulation of EIF2AK3-mediated unfolded protein response" RELATED [HGNC:3255] +synonym: "positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "positive regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "positive regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "positive regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "positive regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "up regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "up regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up regulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "up-regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "up-regulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of PERK branch of UPR" EXACT [GOC:TermGenie] +synonym: "upregulation of PERK signaling in response to endoplasmic reticulum stress" RELATED [GOC:TermGenie] +synonym: "upregulation of PERK-mediated unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of PKR-like ER kinase signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of UPR signaling by PERK stress sensor" EXACT [GOC:TermGenie] +is_a: GO:1900103 ! positive regulation of endoplasmic reticulum unfolded protein response +is_a: GO:1903897 ! regulation of PERK-mediated unfolded protein response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036499 ! PERK-mediated unfolded protein response +relationship: positively_regulates GO:0036499 ! PERK-mediated unfolded protein response +created_by: bf +creation_date: 2015-02-09T10:18:32Z + +[Term] +id: GO:1903900 +name: regulation of viral life cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral life cycle." [GO_REF:0000058, GOC:TermGenie, PMID:18005716] +synonym: "regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "regulation of viral replication" RELATED [GOC:TermGenie] +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019058 ! viral life cycle +relationship: regulates GO:0019058 ! viral life cycle +created_by: pga +creation_date: 2015-02-09T10:22:07Z + +[Term] +id: GO:1903901 +name: negative regulation of viral life cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle." [GO_REF:0000058, GOC:TermGenie, PMID:18005716] +synonym: "down regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "down regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "down regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "down regulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "down regulation of viral replication" RELATED [GOC:TermGenie] +synonym: "down-regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "down-regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "down-regulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral replication" RELATED [GOC:TermGenie] +synonym: "downregulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "downregulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "downregulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "downregulation of viral replication" RELATED [GOC:TermGenie] +synonym: "inhibition of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "inhibition of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "inhibition of viral life cycle" NARROW [GOC:TermGenie] +synonym: "inhibition of viral replication" RELATED [GOC:TermGenie] +synonym: "negative regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "negative regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "negative regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "negative regulation of viral replication" RELATED [GOC:TermGenie] +is_a: GO:0048525 ! negative regulation of viral process +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019058 ! viral life cycle +relationship: negatively_regulates GO:0019058 ! viral life cycle +created_by: pga +creation_date: 2015-02-09T10:22:16Z + +[Term] +id: GO:1903902 +name: positive regulation of viral life cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral life cycle." [GO_REF:0000058, GOC:TermGenie, PMID:18005716] +synonym: "activation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "activation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "activation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "activation of viral life cycle" NARROW [GOC:TermGenie] +synonym: "activation of viral replication" RELATED [GOC:TermGenie] +synonym: "positive regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "positive regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "positive regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "positive regulation of viral replication" RELATED [GOC:TermGenie] +synonym: "up regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "up regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "up regulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of viral replication" RELATED [GOC:TermGenie] +synonym: "up-regulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "up-regulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "up-regulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral replication" RELATED [GOC:TermGenie] +synonym: "upregulation of lytic viral life cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of viral assembly, maturation, egress, and release" NARROW [GOC:TermGenie] +synonym: "upregulation of viral infectious cycle" RELATED [GOC:TermGenie] +synonym: "upregulation of viral life cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of viral replication" RELATED [GOC:TermGenie] +is_a: GO:0048524 ! positive regulation of viral process +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019058 ! viral life cycle +relationship: positively_regulates GO:0019058 ! viral life cycle +created_by: pga +creation_date: 2015-02-09T10:22:25Z + +[Term] +id: GO:1903903 +name: regulation of establishment of T cell polarity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie] +is_a: GO:0050863 ! regulation of T cell activation +is_a: GO:2000114 ! regulation of establishment of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001768 ! establishment of T cell polarity +relationship: regulates GO:0001768 ! establishment of T cell polarity +created_by: als +creation_date: 2015-02-09T10:50:21Z + +[Term] +id: GO:1903904 +name: negative regulation of establishment of T cell polarity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of T cell polarity" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of T-cell polarity" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] +synonym: "inhibition of T cell polarization" NARROW [GOC:TermGenie] +synonym: "inhibition of T lymphocyte polarization" NARROW [GOC:TermGenie] +synonym: "inhibition of T-cell polarization" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie] +is_a: GO:0050868 ! negative regulation of T cell activation +is_a: GO:1903903 ! regulation of establishment of T cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001768 ! establishment of T cell polarity +relationship: negatively_regulates GO:0001768 ! establishment of T cell polarity +created_by: als +creation_date: 2015-02-09T10:50:30Z + +[Term] +id: GO:1903905 +name: positive regulation of establishment of T cell polarity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "activation of establishment of T cell polarity" NARROW [GOC:TermGenie] +synonym: "activation of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] +synonym: "activation of establishment of T-cell polarity" NARROW [GOC:TermGenie] +synonym: "activation of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] +synonym: "activation of T cell polarization" NARROW [GOC:TermGenie] +synonym: "activation of T lymphocyte polarization" NARROW [GOC:TermGenie] +synonym: "activation of T-cell polarization" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] +synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie] +synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] +synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie] +is_a: GO:0050870 ! positive regulation of T cell activation +is_a: GO:1903903 ! regulation of establishment of T cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001768 ! establishment of T cell polarity +relationship: positively_regulates GO:0001768 ! establishment of T cell polarity +created_by: als +creation_date: 2015-02-09T10:50:40Z + +[Term] +id: GO:1903906 +name: regulation of plasma membrane raft polarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plasma membrane raft polarization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044858 ! plasma membrane raft polarization +relationship: regulates GO:0044858 ! plasma membrane raft polarization +created_by: als +creation_date: 2015-02-09T10:53:56Z + +[Term] +id: GO:1903907 +name: negative regulation of plasma membrane raft polarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "down regulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +synonym: "downregulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +synonym: "inhibition of plasma membrane raft polarization" NARROW [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903906 ! regulation of plasma membrane raft polarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044858 ! plasma membrane raft polarization +relationship: negatively_regulates GO:0044858 ! plasma membrane raft polarization +created_by: als +creation_date: 2015-02-09T10:54:05Z + +[Term] +id: GO:1903908 +name: positive regulation of plasma membrane raft polarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "activation of plasma membrane raft polarization" NARROW [GOC:TermGenie] +synonym: "up regulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +synonym: "upregulation of plasma membrane raft polarization" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903906 ! regulation of plasma membrane raft polarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044858 ! plasma membrane raft polarization +relationship: positively_regulates GO:0044858 ! plasma membrane raft polarization +created_by: als +creation_date: 2015-02-09T10:54:15Z + +[Term] +id: GO:1903909 +name: regulation of receptor clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor clustering." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043113 ! receptor clustering +relationship: regulates GO:0043113 ! receptor clustering +created_by: als +creation_date: 2015-02-09T10:56:33Z + +[Term] +id: GO:1903910 +name: negative regulation of receptor clustering +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "down regulation of receptor clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor clustering" EXACT [GOC:TermGenie] +synonym: "inhibition of receptor clustering" NARROW [GOC:TermGenie] +is_a: GO:1903909 ! regulation of receptor clustering +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043113 ! receptor clustering +relationship: negatively_regulates GO:0043113 ! receptor clustering +created_by: als +creation_date: 2015-02-09T10:56:42Z + +[Term] +id: GO:1903911 +name: positive regulation of receptor clustering +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor clustering." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "activation of receptor clustering" NARROW [GOC:TermGenie] +synonym: "up regulation of receptor clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1903909 ! regulation of receptor clustering +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043113 ! receptor clustering +relationship: positively_regulates GO:0043113 ! receptor clustering +created_by: als +creation_date: 2015-02-09T10:56:51Z + +[Term] +id: GO:1903912 +name: negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16835242] +synonym: "down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "downregulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "inhibition of eiF2alpha phosphorylation in response to ER stress" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [] +synonym: "negative regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "negative regulation of ER stress-induced eIF2 alpha phosphorylation" EXACT [GOC:bf] +synonym: "negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:1903573 ! negative regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036492 ! eiF2alpha phosphorylation in response to endoplasmic reticulum stress +relationship: negatively_regulates GO:0036492 ! eiF2alpha phosphorylation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-09T10:58:55Z + +[Term] +id: GO:1903913 +name: regulation of fusion of virus membrane with host plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "regulation of viral envelope fusion" BROAD [GOC:TermGenie] +synonym: "regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0046596 ! regulation of viral entry into host cell +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +relationship: regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +created_by: als +creation_date: 2015-02-09T11:13:19Z + +[Term] +id: GO:1903914 +name: negative regulation of fusion of virus membrane with host plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "down regulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "down regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "down regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "down-regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "downregulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "downregulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "inhibition of fusion of virus membrane with host plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "inhibition of viral envelope fusion with host cell membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of viral envelope fusion with host membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of viral envelope fusion with host plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of viral penetration via membrane fusion" NARROW [GOC:TermGenie] +synonym: "inhibition of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "negative regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0046597 ! negative regulation of viral entry into host cell +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903913 ! regulation of fusion of virus membrane with host plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +relationship: negatively_regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +created_by: als +creation_date: 2015-02-09T11:13:32Z + +[Term] +id: GO:1903915 +name: positive regulation of fusion of virus membrane with host plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] +synonym: "activation of fusion of virus membrane with host plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "activation of viral envelope fusion with host cell membrane" NARROW [GOC:TermGenie] +synonym: "activation of viral envelope fusion with host membrane" NARROW [GOC:TermGenie] +synonym: "activation of viral envelope fusion with host plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of viral penetration via membrane fusion" NARROW [GOC:TermGenie] +synonym: "activation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "positive regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "up regulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "up regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "up-regulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +synonym: "upregulation of fusion of virus membrane with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of viral entry into host cell via membrane fusion with the plasma membrane" RELATED [GOC:TermGenie] +synonym: "upregulation of viral envelope fusion with host cell membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of viral envelope fusion with host membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of viral envelope fusion with host plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of viral penetration via membrane fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of viral-cell fusion molecule activity" RELATED [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0046598 ! positive regulation of viral entry into host cell +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903913 ! regulation of fusion of virus membrane with host plasma membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +relationship: positively_regulates GO:0019064 ! fusion of virus membrane with host plasma membrane +created_by: als +creation_date: 2015-02-09T11:13:41Z + +[Term] +id: GO:1903916 +name: regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [] +synonym: "regulation of eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "regulation of ER stress-induced eIF2 alpha dephosphorylation" EXACT [GOC:bf] +synonym: "regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:0032535 ! regulation of cellular component size +is_a: GO:0035304 ! regulation of protein dephosphorylation +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036497 ! eIF2alpha dephosphorylation in response to endoplasmic reticulum stress +relationship: regulates GO:0036497 ! eIF2alpha dephosphorylation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-09T11:18:14Z + +[Term] +id: GO:1903917 +name: positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11381086] +synonym: "activation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "activation of eIF2alpha dephosphorylation in response to ER stress" NARROW [GOC:TermGenie] +synonym: "activation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" RELATED [] +synonym: "positive regulation of eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER stress-induced eIF2 alpha dephosphorylation" EXACT [GOC:bf] +synonym: "positive regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "up regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +is_a: GO:0035307 ! positive regulation of protein dephosphorylation +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903916 ! regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation +is_a: GO:1905898 ! positive regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036497 ! eIF2alpha dephosphorylation in response to endoplasmic reticulum stress +relationship: positively_regulates GO:0036497 ! eIF2alpha dephosphorylation in response to endoplasmic reticulum stress +created_by: bf +creation_date: 2015-02-09T11:18:24Z + +[Term] +id: GO:1903918 +name: regulation of actin filament severing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament severing." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "regulation of F-actin severing" EXACT [GOC:TermGenie] +is_a: GO:0032970 ! regulation of actin filament-based process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051014 ! actin filament severing +relationship: regulates GO:0051014 ! actin filament severing +created_by: als +creation_date: 2015-02-10T11:01:21Z + +[Term] +id: GO:1903919 +name: negative regulation of actin filament severing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "down regulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "down regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "down regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "down regulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "downregulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "downregulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "downregulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "downregulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "inhibition of actin filament severing" NARROW [GOC:TermGenie] +synonym: "inhibition of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "inhibition of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "inhibition of F-actin severing" NARROW [GOC:TermGenie] +synonym: "negative regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of F-actin severing" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1903918 ! regulation of actin filament severing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051014 ! actin filament severing +relationship: negatively_regulates GO:0051014 ! actin filament severing +created_by: als +creation_date: 2015-02-10T11:01:31Z + +[Term] +id: GO:1903920 +name: positive regulation of actin filament severing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament severing." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "activation of actin filament severing" NARROW [GOC:TermGenie] +synonym: "activation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "activation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "activation of F-actin severing" NARROW [GOC:TermGenie] +synonym: "positive regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "up regulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "up regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "up regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "up regulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of F-actin severing" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament severing" EXACT [GOC:TermGenie] +synonym: "upregulation of actin filament severing activity" RELATED [GOC:TermGenie] +synonym: "upregulation of barbed-end actin capping/severing activity" RELATED [GOC:TermGenie] +synonym: "upregulation of F-actin severing" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1903918 ! regulation of actin filament severing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051014 ! actin filament severing +relationship: positively_regulates GO:0051014 ! actin filament severing +created_by: als +creation_date: 2015-02-10T11:01:40Z + +[Term] +id: GO:1903921 +name: regulation of protein processing in phagocytic vesicle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +is_a: GO:0070613 ! regulation of protein processing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1900756 ! protein processing in phagocytic vesicle +relationship: regulates GO:1900756 ! protein processing in phagocytic vesicle +created_by: als +creation_date: 2015-02-10T11:16:54Z + +[Term] +id: GO:1903922 +name: negative regulation of protein processing in phagocytic vesicle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "down regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "down regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "down regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "down regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "down regulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "down-regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "downregulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "downregulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "downregulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "downregulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "downregulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "inhibition of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "inhibition of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "inhibition of protein maturation by peptide bond cleavage in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein maturation by peptide bond cleavage in phagosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein maturation by peptide bond hydrolysis in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein maturation by peptide bond hydrolysis in phagosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "inhibition of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "inhibition of protein processing in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein processing in phagosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "negative regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +is_a: GO:0010955 ! negative regulation of protein processing +is_a: GO:1903921 ! regulation of protein processing in phagocytic vesicle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1900756 ! protein processing in phagocytic vesicle +relationship: negatively_regulates GO:1900756 ! protein processing in phagocytic vesicle +created_by: als +creation_date: 2015-02-10T11:17:05Z + +[Term] +id: GO:1903923 +name: positive regulation of protein processing in phagocytic vesicle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23325791] +synonym: "activation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "activation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "activation of protein maturation by peptide bond cleavage in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein maturation by peptide bond cleavage in phagosome" NARROW [GOC:TermGenie] +synonym: "activation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein maturation by peptide bond hydrolysis in phagosome" NARROW [GOC:TermGenie] +synonym: "activation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "activation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "activation of protein processing in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein processing in phagosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "positive regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "up regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "up regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "up regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "up regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "up regulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "up-regulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein processing in phagosome" EXACT [GOC:TermGenie] +synonym: "upregulation of peptidolysis during protein maturation in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "upregulation of peptidolysis during protein maturation in phagosome" RELATED [GOC:TermGenie] +synonym: "upregulation of protein maturation by peptide bond cleavage in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein maturation by peptide bond cleavage in phagosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein maturation by peptide bond hydrolysis in phagosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein maturation by proteolysis in phagocytic vesicle" RELATED [GOC:TermGenie] +synonym: "upregulation of protein maturation by proteolysis in phagosome" RELATED [GOC:TermGenie] +synonym: "upregulation of protein processing in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein processing in phagosome" EXACT [GOC:TermGenie] +is_a: GO:0010954 ! positive regulation of protein processing +is_a: GO:1903921 ! regulation of protein processing in phagocytic vesicle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1900756 ! protein processing in phagocytic vesicle +relationship: positively_regulates GO:1900756 ! protein processing in phagocytic vesicle +created_by: als +creation_date: 2015-02-10T11:17:14Z + +[Term] +id: GO:1903924 +name: estradiol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with estradiol." [GO_REF:0000067, GOC:TermGenie, PMID:9048584] +is_a: GO:0005496 ! steroid binding +is_a: GO:0099130 ! estrogen binding +created_by: sl +creation_date: 2015-02-11T00:11:34Z + +[Term] +id: GO:1903925 +name: response to bisphenol A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22957036] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-02-11T00:16:46Z + +[Term] +id: GO:1903926 +name: cellular response to bisphenol A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22957036] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1903925 ! response to bisphenol A +created_by: sl +creation_date: 2015-02-11T00:17:04Z + +[Term] +id: GO:1903927 +name: response to cyanide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21854848] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010033 ! response to organic substance +created_by: sl +creation_date: 2015-02-11T19:04:19Z + +[Term] +id: GO:1903928 +name: cellular response to cyanide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21854848] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1903927 ! response to cyanide +created_by: sl +creation_date: 2015-02-11T19:04:28Z + +[Term] +id: GO:1903929 +name: primary palate development +namespace: biological_process +def: "The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mgi_curators, GOC:TermGenie, PMID:24644145, PMID:25504820] +synonym: "palatum primarium development" RELATED [GOC:TermGenie] +synonym: "primary palate process development" EXACT [GOC:TermGenie] +synonym: "primitive palate development" RELATED [GOC:TermGenie] +synonym: "processus palatinus medianus development" RELATED [GOC:TermGenie] +is_a: GO:0060021 ! roof of mouth development +created_by: cls +creation_date: 2015-02-11T22:42:38Z + +[Term] +id: GO:1903930 +name: regulation of pyrimidine-containing compound salvage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage." [GO_REF:0000058, GOC:TermGenie, PMID:23695302] +synonym: "regulation of pyrimidine salvage" RELATED [GOC:TermGenie] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008655 ! pyrimidine-containing compound salvage +relationship: regulates GO:0008655 ! pyrimidine-containing compound salvage +created_by: al +creation_date: 2015-02-12T14:09:05Z + +[Term] +id: GO:1903931 +name: positive regulation of pyrimidine-containing compound salvage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage." [GO_REF:0000058, GOC:TermGenie, PMID:23695302] +synonym: "activation of pyrimidine salvage" RELATED [GOC:TermGenie] +synonym: "activation of pyrimidine-containing compound salvage" NARROW [GOC:TermGenie] +synonym: "positive regulation of pyrimidine salvage" RELATED [GOC:TermGenie] +synonym: "up regulation of pyrimidine salvage" RELATED [GOC:TermGenie] +synonym: "up regulation of pyrimidine-containing compound salvage" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine salvage" RELATED [GOC:TermGenie] +synonym: "up-regulation of pyrimidine-containing compound salvage" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine salvage" RELATED [GOC:TermGenie] +synonym: "upregulation of pyrimidine-containing compound salvage" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process +is_a: GO:1903930 ! regulation of pyrimidine-containing compound salvage +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008655 ! pyrimidine-containing compound salvage +relationship: positively_regulates GO:0008655 ! pyrimidine-containing compound salvage +created_by: al +creation_date: 2015-02-12T14:09:15Z + +[Term] +id: GO:1903932 +name: regulation of DNA primase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA primase activity." [GO_REF:0000059, GOC:TermGenie, PMID:14766746] +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0051338 ! regulation of transferase activity +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +is_a: GO:2001141 ! regulation of RNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003896 ! DNA primase activity +relationship: regulates GO:0003896 ! DNA primase activity +created_by: mah +creation_date: 2015-02-12T14:28:26Z + +[Term] +id: GO:1903933 +name: negative regulation of DNA primase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity." [GO_REF:0000059, GOC:TermGenie, PMID:14766746] +synonym: "down regulation of DNA primase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA primase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA primase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA primase activity" NARROW [GOC:TermGenie] +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1902679 ! negative regulation of RNA biosynthetic process +is_a: GO:1903932 ! regulation of DNA primase activity +is_a: GO:2000104 ! negative regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003896 ! DNA primase activity +relationship: negatively_regulates GO:0003896 ! DNA primase activity +created_by: mah +creation_date: 2015-02-12T14:28:36Z + +[Term] +id: GO:1903934 +name: positive regulation of DNA primase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA primase activity." [GO_REF:0000059, GOC:TermGenie, PMID:14766746] +synonym: "activation of DNA primase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA primase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA primase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA primase activity" EXACT [GOC:TermGenie] +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1902680 ! positive regulation of RNA biosynthetic process +is_a: GO:1903932 ! regulation of DNA primase activity +is_a: GO:2000105 ! positive regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003896 ! DNA primase activity +relationship: positively_regulates GO:0003896 ! DNA primase activity +created_by: mah +creation_date: 2015-02-12T14:28:45Z + +[Term] +id: GO:1903935 +name: response to sodium arsenite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18674524] +is_a: GO:0009635 ! response to herbicide +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0017085 ! response to insecticide +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0046685 ! response to arsenic-containing substance +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1902074 ! response to salt +created_by: sl +creation_date: 2015-02-12T20:54:33Z + +[Term] +id: GO:1903936 +name: cellular response to sodium arsenite +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18674524] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071243 ! cellular response to arsenic-containing substance +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1902075 ! cellular response to salt +is_a: GO:1903935 ! response to sodium arsenite +created_by: sl +creation_date: 2015-02-12T20:54:53Z + +[Term] +id: GO:1903937 +name: response to acrylamide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16292499] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-02-12T22:00:24Z + +[Term] +id: GO:1903938 +name: cellular response to acrylamide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16292499] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1903937 ! response to acrylamide +created_by: sl +creation_date: 2015-02-12T22:00:34Z + +[Term] +id: GO:1903939 +name: regulation of TORC2 signaling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of TORC2 signaling." [GO_REF:0000058, GOC:TermGenie, PMID:24247430] +synonym: "regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +is_a: GO:0032006 ! regulation of TOR signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038203 ! TORC2 signaling +relationship: regulates GO:0038203 ! TORC2 signaling +created_by: al +creation_date: 2015-02-16T18:28:39Z + +[Term] +id: GO:1903940 +name: negative regulation of TORC2 signaling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling." [GO_REF:0000058, GOC:TermGenie, PMID:24247430] +synonym: "down regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of TORC2 signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of TORC2 signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of TORC2 signaling" EXACT [GOC:TermGenie] +synonym: "inhibition of TORC2 signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of TORC2 signaling" NARROW [GOC:TermGenie] +synonym: "negative regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +is_a: GO:0032007 ! negative regulation of TOR signaling +is_a: GO:1903939 ! regulation of TORC2 signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038203 ! TORC2 signaling +relationship: negatively_regulates GO:0038203 ! TORC2 signaling +created_by: al +creation_date: 2015-02-16T18:28:50Z + +[Term] +id: GO:1903941 +name: negative regulation of respiratory gaseous exchange +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] +synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +synonym: "inhibition of respiratory gaseous exchange" NARROW [GOC:TermGenie] +is_a: GO:0043576 ! regulation of respiratory gaseous exchange +is_a: GO:0051241 ! negative regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system +relationship: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system +created_by: sl +creation_date: 2015-02-17T20:26:24Z + +[Term] +id: GO:1903942 +name: positive regulation of respiratory gaseous exchange +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] +synonym: "activation of respiratory gaseous exchange" NARROW [GOC:TermGenie] +synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] +is_a: GO:0043576 ! regulation of respiratory gaseous exchange +is_a: GO:0051240 ! positive regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system +relationship: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system +created_by: sl +creation_date: 2015-02-17T20:26:35Z + +[Term] +id: GO:1903943 +name: regulation of hepatocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] +synonym: "regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097284 ! hepatocyte apoptotic process +relationship: regulates GO:0097284 ! hepatocyte apoptotic process +created_by: sl +creation_date: 2015-02-19T12:54:40Z + +[Term] +id: GO:1903944 +name: negative regulation of hepatocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] +synonym: "down regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of hepatocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +is_a: GO:1903943 ! regulation of hepatocyte apoptotic process +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097284 ! hepatocyte apoptotic process +relationship: negatively_regulates GO:0097284 ! hepatocyte apoptotic process +created_by: sl +creation_date: 2015-02-19T12:54:50Z + +[Term] +id: GO:1903945 +name: positive regulation of hepatocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] +synonym: "activation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of hepatocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1903943 ! regulation of hepatocyte apoptotic process +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097284 ! hepatocyte apoptotic process +relationship: positively_regulates GO:0097284 ! hepatocyte apoptotic process +created_by: sl +creation_date: 2015-02-19T12:54:59Z + +[Term] +id: GO:1903946 +name: negative regulation of ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "down regulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:0098911 ! regulation of ventricular cardiac muscle cell action potential +is_a: GO:0106135 ! negative regulation of cardiac muscle cell contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086005 ! ventricular cardiac muscle cell action potential +relationship: negatively_regulates GO:0086005 ! ventricular cardiac muscle cell action potential +created_by: nc +creation_date: 2015-02-20T14:31:55Z + +[Term] +id: GO:1903947 +name: positive regulation of ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "activation of ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up regulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:0098911 ! regulation of ventricular cardiac muscle cell action potential +is_a: GO:0106134 ! positive regulation of cardiac muscle cell contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086005 ! ventricular cardiac muscle cell action potential +relationship: positively_regulates GO:0086005 ! ventricular cardiac muscle cell action potential +created_by: nc +creation_date: 2015-02-20T14:32:04Z + +[Term] +id: GO:1903948 +name: negative regulation of atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "down regulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of atrial cardiac muscle cell action potential" NARROW [GOC:TermGenie] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:0098910 ! regulation of atrial cardiac muscle cell action potential +is_a: GO:0106135 ! negative regulation of cardiac muscle cell contraction +is_a: GO:1903780 ! negative regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086014 ! atrial cardiac muscle cell action potential +relationship: negatively_regulates GO:0086014 ! atrial cardiac muscle cell action potential +created_by: nc +creation_date: 2015-02-20T14:36:33Z + +[Term] +id: GO:1903949 +name: positive regulation of atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "activation of atrial cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up regulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:0098910 ! regulation of atrial cardiac muscle cell action potential +is_a: GO:0106134 ! positive regulation of cardiac muscle cell contraction +is_a: GO:1903781 ! positive regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086014 ! atrial cardiac muscle cell action potential +relationship: positively_regulates GO:0086014 ! atrial cardiac muscle cell action potential +created_by: nc +creation_date: 2015-02-20T14:36:42Z + +[Term] +id: GO:1903950 +name: negative regulation of AV node cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of AV node cell action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:0098904 ! regulation of AV node cell action potential +is_a: GO:1903780 ! negative regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086016 ! AV node cell action potential +relationship: negatively_regulates GO:0086016 ! AV node cell action potential +created_by: nc +creation_date: 2015-02-20T14:59:41Z + +[Term] +id: GO:1903951 +name: positive regulation of AV node cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "activation of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of AV node cell action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:0098904 ! regulation of AV node cell action potential +is_a: GO:1903781 ! positive regulation of cardiac conduction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086016 ! AV node cell action potential +relationship: positively_regulates GO:0086016 ! AV node cell action potential +created_by: nc +creation_date: 2015-02-20T14:59:50Z + +[Term] +id: GO:1903952 +name: regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +is_a: GO:0098910 ! regulation of atrial cardiac muscle cell action potential +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:1905031 ! regulation of membrane repolarization during cardiac muscle cell action potential +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +relationship: regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +created_by: nc +creation_date: 2015-02-24T10:32:06Z + +[Term] +id: GO:1903953 +name: negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "down regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity +is_a: GO:1903948 ! negative regulation of atrial cardiac muscle cell action potential +is_a: GO:1903952 ! regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +is_a: GO:1905032 ! negative regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +relationship: negatively_regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +created_by: nc +creation_date: 2015-02-24T10:32:16Z + +[Term] +id: GO:1903954 +name: positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] +synonym: "activation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization" EXACT [GOC:TermGenie] +is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity +is_a: GO:1903949 ! positive regulation of atrial cardiac muscle cell action potential +is_a: GO:1903952 ! regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +is_a: GO:1905033 ! positive regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +relationship: positively_regulates GO:0086089 ! voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization +created_by: nc +creation_date: 2015-02-24T10:32:24Z + +[Term] +id: GO:1903955 +name: positive regulation of protein targeting to mitochondrion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24270810] +comment: An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype. +synonym: "activation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "activation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "activation of protein import into mitochondrion" NARROW [GOC:TermGenie] +synonym: "activation of protein targeting to mitochondria" NARROW [GOC:TermGenie] +synonym: "activation of protein targeting to mitochondrion" NARROW [GOC:TermGenie] +synonym: "activation of protein-mitochondrial targeting" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "positive regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "up regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "up regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "up regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "up regulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "up regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "up-regulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial protein import" RELATED [GOC:TermGenie] +synonym: "upregulation of mitochondrial translocation" RELATED [GOC:TermGenie] +synonym: "upregulation of protein import into mitochondrion" EXACT [GOC:TermGenie] +synonym: "upregulation of protein targeting to mitochondria" EXACT [GOC:TermGenie] +synonym: "upregulation of protein targeting to mitochondrion" EXACT [GOC:TermGenie] +synonym: "upregulation of protein-mitochondrial targeting" EXACT [GOC:TermGenie] +is_a: GO:0010822 ! positive regulation of mitochondrion organization +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1903214 ! regulation of protein targeting to mitochondrion +is_a: GO:1903749 ! positive regulation of establishment of protein localization to mitochondrion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006626 ! protein targeting to mitochondrion +relationship: positively_regulates GO:0006626 ! protein targeting to mitochondrion +created_by: pad +creation_date: 2015-02-24T16:58:21Z + +[Term] +id: GO:1903956 +name: response to latrunculin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18951025] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097305 ! response to alcohol +created_by: al +creation_date: 2015-02-24T17:00:11Z + +[Term] +id: GO:1903957 +name: cellular response to latrunculin B +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18951025] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1903956 ! response to latrunculin B +created_by: al +creation_date: 2015-02-24T17:00:21Z + +[Term] +id: GO:1903958 +name: nitric-oxide synthase complex +namespace: cellular_component +def: "A protein complex which is capable of nitric-oxide synthase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:25417112] +comment: An example of this is NOS2 in human (P35228) in PMID:25417112 (inferred from direct assay). +synonym: "iNOS-S100A8/A9 complex" NARROW [] +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2015-02-25T10:45:01Z + +[Term] +id: GO:1903959 +name: regulation of anion transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +is_a: GO:0034765 ! regulation of ion transmembrane transport +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098656 ! anion transmembrane transport +relationship: regulates GO:0098656 ! anion transmembrane transport +created_by: pr +creation_date: 2015-02-25T13:52:25Z + +[Term] +id: GO:1903960 +name: negative regulation of anion transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "down regulation of anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of anion transmembrane transport" NARROW [GOC:TermGenie] +is_a: GO:0034766 ! negative regulation of ion transmembrane transport +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098656 ! anion transmembrane transport +relationship: negatively_regulates GO:0098656 ! anion transmembrane transport +created_by: pr +creation_date: 2015-02-25T13:52:35Z + +[Term] +id: GO:1903961 +name: positive regulation of anion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] +synonym: "activation of anion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "up regulation of anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of anion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of anion transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:0034767 ! positive regulation of ion transmembrane transport +is_a: GO:1903793 ! positive regulation of anion transport +is_a: GO:1903959 ! regulation of anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098656 ! anion transmembrane transport +relationship: positively_regulates GO:0098656 ! anion transmembrane transport +created_by: pr +creation_date: 2015-02-25T13:52:44Z + +[Term] +id: GO:1903962 +name: arachidonate transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of arachidonate from one side of a membrane to the other." [GO_REF:0000066, GOC:bhm, GOC:TermGenie, PMID:15642721] +comment: An example of this is S100A9 in human (P06702) in PMID:15642721 (inferred from direct assay). +synonym: "arachidonate transporter activity" RELATED [] +synonym: "arachidonic acid transporter activity" RELATED [] +is_a: GO:0005324 ! long-chain fatty acid transporter activity +is_a: GO:0015245 ! fatty acid transmembrane transporter activity +is_a: GO:0071714 ! icosanoid transmembrane transporter activity +relationship: part_of GO:1903963 ! arachidonate transport +created_by: bhm +creation_date: 2015-02-25T15:51:12Z + +[Term] +id: GO:1903963 +name: arachidonate transport +namespace: biological_process +def: "The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO_REF:0000065, GOC:bhm, GOC:TermGenie, PMID:15642721] +synonym: "arachidonic acid transport" EXACT [] +is_a: GO:0015909 ! long-chain fatty acid transport +is_a: GO:0071715 ! icosanoid transport +created_by: bhm +creation_date: 2015-02-25T16:06:14Z + +[Term] +id: GO:1903964 +name: monounsaturated fatty acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving monounsaturated fatty acid." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:16443825] +comment: For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast. +synonym: "monounsaturated fatty acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0033559 ! unsaturated fatty acid metabolic process +created_by: pr +creation_date: 2015-02-25T20:35:48Z + +[Term] +id: GO:1903965 +name: monounsaturated fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:16443825] +synonym: "monounsaturated fatty acid breakdown" EXACT [GOC:TermGenie] +synonym: "monounsaturated fatty acid catabolism" EXACT [GOC:TermGenie] +synonym: "monounsaturated fatty acid degradation" EXACT [GOC:TermGenie] +is_a: GO:0009062 ! fatty acid catabolic process +is_a: GO:1903964 ! monounsaturated fatty acid metabolic process +created_by: pr +creation_date: 2015-02-25T20:35:58Z + +[Term] +id: GO:1903966 +name: monounsaturated fatty acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:16443825] +comment: For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast. +synonym: "monounsaturated fatty acid anabolism" EXACT [GOC:TermGenie] +synonym: "monounsaturated fatty acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "monounsaturated fatty acid formation" EXACT [GOC:TermGenie] +synonym: "monounsaturated fatty acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:1903964 ! monounsaturated fatty acid metabolic process +created_by: pr +creation_date: 2015-02-25T20:36:07Z + +[Term] +id: GO:1903967 +name: response to micafungin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16928959] +is_a: GO:0033993 ! response to lipid +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901652 ! response to peptide +created_by: al +creation_date: 2015-02-27T09:57:38Z + +[Term] +id: GO:1903968 +name: cellular response to micafungin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16928959] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901653 ! cellular response to peptide +is_a: GO:1903967 ! response to micafungin +created_by: al +creation_date: 2015-02-27T09:57:44Z + +[Term] +id: GO:1903969 +name: regulation of response to macrophage colony-stimulating factor +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +is_a: GO:0060759 ! regulation of response to cytokine stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036005 ! response to macrophage colony-stimulating factor +relationship: regulates GO:0036005 ! response to macrophage colony-stimulating factor +created_by: nc +creation_date: 2015-03-02T14:41:02Z + +[Term] +id: GO:1903970 +name: negative regulation of response to macrophage colony-stimulating factor +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "down regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "down regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "downregulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "downregulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of response to M-CSF" NARROW [GOC:TermGenie] +synonym: "inhibition of response to macrophage colony-stimulating factor" NARROW [GOC:TermGenie] +synonym: "inhibition of response to macrophage colony-stimulating factor stimulus" NARROW [GOC:TermGenie] +synonym: "negative regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "negative regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +is_a: GO:0060761 ! negative regulation of response to cytokine stimulus +is_a: GO:1903969 ! regulation of response to macrophage colony-stimulating factor +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036005 ! response to macrophage colony-stimulating factor +relationship: negatively_regulates GO:0036005 ! response to macrophage colony-stimulating factor +created_by: nc +creation_date: 2015-03-02T14:41:08Z + +[Term] +id: GO:1903971 +name: positive regulation of response to macrophage colony-stimulating factor +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of response to M-CSF" NARROW [GOC:TermGenie] +synonym: "activation of response to macrophage colony-stimulating factor" NARROW [GOC:TermGenie] +synonym: "activation of response to macrophage colony-stimulating factor stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "up regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "up regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of response to M-CSF" EXACT [GOC:TermGenie] +synonym: "upregulation of response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "upregulation of response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +is_a: GO:0060760 ! positive regulation of response to cytokine stimulus +is_a: GO:1903969 ! regulation of response to macrophage colony-stimulating factor +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036005 ! response to macrophage colony-stimulating factor +relationship: positively_regulates GO:0036005 ! response to macrophage colony-stimulating factor +created_by: nc +creation_date: 2015-03-02T14:41:14Z + +[Term] +id: GO:1903972 +name: regulation of cellular response to macrophage colony-stimulating factor stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:1903969 ! regulation of response to macrophage colony-stimulating factor +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +relationship: regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +created_by: nc +creation_date: 2015-03-02T14:50:14Z + +[Term] +id: GO:1903973 +name: negative regulation of cellular response to macrophage colony-stimulating factor stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to M-CSF stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to macrophage colony-stimulating factor" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to macrophage colony-stimulating factor stimulus" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1903970 ! negative regulation of response to macrophage colony-stimulating factor +is_a: GO:1903972 ! regulation of cellular response to macrophage colony-stimulating factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +relationship: negatively_regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +created_by: nc +creation_date: 2015-03-02T14:50:20Z + +[Term] +id: GO:1903974 +name: positive regulation of cellular response to macrophage colony-stimulating factor stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of cellular response to M-CSF stimulus" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to macrophage colony-stimulating factor" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to macrophage colony-stimulating factor stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to M-CSF stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to macrophage colony-stimulating factor" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to macrophage colony-stimulating factor stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1903971 ! positive regulation of response to macrophage colony-stimulating factor +is_a: GO:1903972 ! regulation of cellular response to macrophage colony-stimulating factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +relationship: positively_regulates GO:0036006 ! cellular response to macrophage colony-stimulating factor stimulus +created_by: nc +creation_date: 2015-03-02T14:50:25Z + +[Term] +id: GO:1903975 +name: regulation of glial cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014013 ! regulation of gliogenesis +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008347 ! glial cell migration +relationship: regulates GO:0008347 ! glial cell migration +created_by: nc +creation_date: 2015-03-02T15:13:31Z + +[Term] +id: GO:1903976 +name: negative regulation of glial cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of glia cell migration" NARROW [GOC:TermGenie] +synonym: "inhibition of glial cell migration" NARROW [GOC:TermGenie] +synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014014 ! negative regulation of gliogenesis +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:1903975 ! regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008347 ! glial cell migration +relationship: negatively_regulates GO:0008347 ! glial cell migration +created_by: nc +creation_date: 2015-03-02T15:13:38Z + +[Term] +id: GO:1903977 +name: positive regulation of glial cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of glia cell migration" NARROW [GOC:TermGenie] +synonym: "activation of glial cell migration" NARROW [GOC:TermGenie] +synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014015 ! positive regulation of gliogenesis +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:1903975 ! regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008347 ! glial cell migration +relationship: positively_regulates GO:0008347 ! glial cell migration +created_by: nc +creation_date: 2015-03-02T15:13:43Z + +[Term] +id: GO:1903978 +name: regulation of microglial cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microglial cell activation." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +is_a: GO:0043030 ! regulation of macrophage activation +is_a: GO:0150077 ! regulation of neuroinflammatory response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001774 ! microglial cell activation +relationship: regulates GO:0001774 ! microglial cell activation +created_by: nc +creation_date: 2015-03-02T15:17:33Z + +[Term] +id: GO:1903979 +name: negative regulation of microglial cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of microglial cell activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of microglial cell activation" EXACT [GOC:TermGenie] +synonym: "downregulation of microglial cell activation" EXACT [GOC:TermGenie] +synonym: "inhibition of microglial cell activation" NARROW [GOC:TermGenie] +is_a: GO:0043031 ! negative regulation of macrophage activation +is_a: GO:0150079 ! negative regulation of neuroinflammatory response +is_a: GO:1903978 ! regulation of microglial cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001774 ! microglial cell activation +relationship: negatively_regulates GO:0001774 ! microglial cell activation +created_by: nc +creation_date: 2015-03-02T15:17:39Z + +[Term] +id: GO:1903980 +name: positive regulation of microglial cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microglial cell activation." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of microglial cell activation" NARROW [GOC:TermGenie] +synonym: "up regulation of microglial cell activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of microglial cell activation" EXACT [GOC:TermGenie] +synonym: "upregulation of microglial cell activation" EXACT [GOC:TermGenie] +is_a: GO:0043032 ! positive regulation of macrophage activation +is_a: GO:0150078 ! positive regulation of neuroinflammatory response +is_a: GO:1903978 ! regulation of microglial cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001774 ! microglial cell activation +relationship: positively_regulates GO:0001774 ! microglial cell activation +created_by: nc +creation_date: 2015-03-02T15:17:44Z + +[Term] +id: GO:1903981 +name: enterobactin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with enterobactin." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:21951132] +synonym: "enterochelin binding" EXACT [] +synonym: "siderophore binding" BROAD [] +is_a: GO:0043168 ! anion binding +is_a: GO:0048037 ! cofactor binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mr +creation_date: 2015-03-02T17:21:54Z + +[Term] +id: GO:1903982 +name: negative regulation of microvillus length +namespace: biological_process +def: "A process that decreases the length of a microvillus." [GOC:als, PMID:22114352] +synonym: "down regulation of regulation of microvillus length" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of microvillus length" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of microvillus length" EXACT [GOC:TermGenie] +synonym: "inhibition of regulation of microvillus length" NARROW [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0032532 ! regulation of microvillus length +created_by: als +creation_date: 2015-03-03T13:23:52Z + +[Term] +id: GO:1903983 +name: positive regulation of microvillus length +namespace: biological_process +def: "A process that increases the length of a microvillus." [GOC:als, PMID:22114352] +synonym: "activation of regulation of microvillus length" NARROW [GOC:TermGenie] +synonym: "up regulation of regulation of microvillus length" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of microvillus length" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of microvillus length" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0032532 ! regulation of microvillus length +created_by: als +creation_date: 2015-03-03T13:23:58Z + +[Term] +id: GO:1903984 +name: positive regulation of TRAIL-activated apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24939851] +synonym: "activation of TRAIL-activated apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of TRAIL-activated extrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of TRAIL-induced apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of TRAIL-activated apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of TRAIL-activated extrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of TRAIL-induced apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1902043 ! positive regulation of extrinsic apoptotic signaling pathway via death domain receptors +is_a: GO:1903121 ! regulation of TRAIL-activated apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +relationship: positively_regulates GO:0036462 ! TRAIL-activated apoptotic signaling pathway +created_by: bf +creation_date: 2015-03-03T15:04:21Z + +[Term] +id: GO:1903985 +name: regulation of intestinal D-glucose absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption." [GO_REF:0000058, GOA:als, GOC:TermGenie, PMID:22114352] +is_a: GO:1904478 ! regulation of intestinal absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001951 ! intestinal D-glucose absorption +relationship: regulates GO:0001951 ! intestinal D-glucose absorption +created_by: als +creation_date: 2015-03-04T10:07:55Z + +[Term] +id: GO:1903988 +name: iron ion export across plasma membrane +namespace: biological_process +alt_id: GO:1903414 +def: "The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region." [GO_REF:0000074, GOC:BHF, GOC:kom, GOC:rl, GOC:TermGenie, PMID:15514116] +comment: An example of this is mouse ferroportin (symbol Slc40a1, UniProtKB identifier: Q9JHI9). +synonym: "ferrous iron export" NARROW [] +synonym: "ferrous iron export across plasma membrane" NARROW [] +synonym: "iron cation export" RELATED [] +synonym: "iron(2+) export" RELATED [] +is_a: GO:0034755 ! iron ion transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +created_by: rl +creation_date: 2014-09-03T13:01:37Z + +[Term] +id: GO:1903992 +name: obsolete regulation of protein stabilization +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of protein stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:18573880] +comment: This term was made obsolete because it was created in error. +synonym: "regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "regulation of protein stabilization" EXACT [] +synonym: "regulation of protein stabilization activity" RELATED [GOC:TermGenie] +is_obsolete: true +consider: GO:0031647 +created_by: pga +creation_date: 2015-03-05T13:32:49Z + +[Term] +id: GO:1903993 +name: obsolete negative regulation of protein stabilization +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:18573880] +comment: This term was made obsolete because it was created in error. +synonym: "down regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "down regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "down regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "down regulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "down regulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "down-regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "downregulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "downregulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "downregulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "downregulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "downregulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "inhibition of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "inhibition of positive regulation of protein stability" NARROW [GOC:TermGenie] +synonym: "inhibition of protein sequestering" RELATED [GOC:TermGenie] +synonym: "inhibition of protein stabilization" NARROW [GOC:TermGenie] +synonym: "inhibition of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "negative regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein stabilization" EXACT [] +synonym: "negative regulation of protein stabilization activity" RELATED [GOC:TermGenie] +is_obsolete: true +consider: GO:0031648 +created_by: pga +creation_date: 2015-03-05T13:32:55Z + +[Term] +id: GO:1903994 +name: obsolete positive regulation of protein stabilization +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:18573880] +comment: This term was made obsolete because it was created in error. +synonym: "activation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "activation of positive regulation of protein stability" NARROW [GOC:TermGenie] +synonym: "activation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "activation of protein stabilization" NARROW [GOC:TermGenie] +synonym: "activation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "positive regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein stabilization" EXACT [] +synonym: "positive regulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "up regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "up regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "up regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "up regulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "up regulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "up-regulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein stabilization activity" RELATED [GOC:TermGenie] +synonym: "upregulation of lysosomal protein stabilization" NARROW [GOC:TermGenie] +synonym: "upregulation of positive regulation of protein stability" EXACT [GOC:TermGenie] +synonym: "upregulation of protein sequestering" RELATED [GOC:TermGenie] +synonym: "upregulation of protein stabilization" EXACT [GOC:TermGenie] +synonym: "upregulation of protein stabilization activity" RELATED [GOC:TermGenie] +is_obsolete: true +consider: GO:0050821 +created_by: pga +creation_date: 2015-03-05T13:33:00Z + +[Term] +id: GO:1903995 +name: regulation of non-membrane spanning protein tyrosine kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:10518561] +synonym: "regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:protein-tyrosine O-phosphotransferase activity" BROAD [GOC:TermGenie] +synonym: "regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +is_a: GO:0061097 ! regulation of protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +relationship: regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +created_by: nc +creation_date: 2015-03-05T16:34:35Z + +[Term] +id: GO:1903996 +name: negative regulation of non-membrane spanning protein tyrosine kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:10518561] +synonym: "down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of non-membrane spanning protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of non-specific protein-tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +is_a: GO:0061099 ! negative regulation of protein tyrosine kinase activity +is_a: GO:1903995 ! regulation of non-membrane spanning protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +relationship: negatively_regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +created_by: nc +creation_date: 2015-03-05T16:34:41Z + +[Term] +id: GO:1903997 +name: positive regulation of non-membrane spanning protein tyrosine kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:10518561] +synonym: "activation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" NARROW [GOC:TermGenie] +synonym: "activation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "activation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "activation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "activation of non-membrane spanning protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of non-specific protein-tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "up regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "up regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "up regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of janus kinase 1 activity" NARROW [GOC:TermGenie] +synonym: "upregulation of janus kinase 2 activity" NARROW [GOC:TermGenie] +synonym: "upregulation of janus kinase 3 activity" NARROW [GOC:TermGenie] +synonym: "upregulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] +is_a: GO:0061098 ! positive regulation of protein tyrosine kinase activity +is_a: GO:1903995 ! regulation of non-membrane spanning protein tyrosine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +relationship: positively_regulates GO:0004715 ! non-membrane spanning protein tyrosine kinase activity +created_by: nc +creation_date: 2015-03-05T16:34:46Z + +[Term] +id: GO:1903998 +name: regulation of eating behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eating behavior." [GO_REF:0000058, GOC:TermGenie, PMID:11961051] +synonym: "regulation of eating behaviour" EXACT [GOC:TermGenie] +is_a: GO:0060259 ! regulation of feeding behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042755 ! eating behavior +relationship: regulates GO:0042755 ! eating behavior +created_by: sl +creation_date: 2015-03-05T20:40:22Z + +[Term] +id: GO:1903999 +name: negative regulation of eating behavior +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior." [GO_REF:0000058, GOC:TermGenie, PMID:11961051] +synonym: "down regulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "down regulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "down-regulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "down-regulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "downregulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "downregulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "inhibition of eating behavior" NARROW [GOC:TermGenie] +synonym: "inhibition of eating behaviour" NARROW [GOC:TermGenie] +synonym: "negative regulation of eating behaviour" EXACT [GOC:TermGenie] +is_a: GO:1903998 ! regulation of eating behavior +is_a: GO:2000252 ! negative regulation of feeding behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042755 ! eating behavior +relationship: negatively_regulates GO:0042755 ! eating behavior +created_by: sl +creation_date: 2015-03-05T20:40:28Z + +[Term] +id: GO:1904000 +name: positive regulation of eating behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eating behavior." [GO_REF:0000058, GOC:TermGenie, PMID:11961051] +synonym: "activation of eating behavior" NARROW [GOC:TermGenie] +synonym: "activation of eating behaviour" NARROW [GOC:TermGenie] +synonym: "positive regulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "up regulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "up regulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "up-regulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "up-regulation of eating behaviour" EXACT [GOC:TermGenie] +synonym: "upregulation of eating behavior" EXACT [GOC:TermGenie] +synonym: "upregulation of eating behaviour" EXACT [GOC:TermGenie] +is_a: GO:1903998 ! regulation of eating behavior +is_a: GO:2000253 ! positive regulation of feeding behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042755 ! eating behavior +relationship: positively_regulates GO:0042755 ! eating behavior +created_by: sl +creation_date: 2015-03-05T20:40:35Z + +[Term] +id: GO:1904001 +name: obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage." [GO_REF:0000063, GOC:al, GOC:TermGenie, PMID:23695302] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pr +creation_date: 2015-03-05T21:25:42Z + +[Term] +id: GO:1904002 +name: regulation of sebum secreting cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:16901790] +synonym: "regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990654 ! sebum secreting cell proliferation +relationship: regulates GO:1990654 ! sebum secreting cell proliferation +created_by: hjd +creation_date: 2015-03-06T16:19:44Z + +[Term] +id: GO:1904003 +name: negative regulation of sebum secreting cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:16901790] +synonym: "down regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "down regulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "down-regulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "downregulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "inhibition of sebum secreting cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:1904002 ! regulation of sebum secreting cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990654 ! sebum secreting cell proliferation +relationship: negatively_regulates GO:1990654 ! sebum secreting cell proliferation +created_by: hjd +creation_date: 2015-03-06T16:19:50Z + +[Term] +id: GO:1904004 +name: positive regulation of sebum secreting cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:16901790] +synonym: "activation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "activation of sebum secreting cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "up regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "up regulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "up-regulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of sebocyte proliferation" RELATED [GOC:TermGenie] +synonym: "upregulation of sebum secreting cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:1904002 ! regulation of sebum secreting cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990654 ! sebum secreting cell proliferation +relationship: positively_regulates GO:1990654 ! sebum secreting cell proliferation +created_by: hjd +creation_date: 2015-03-06T16:19:56Z + +[Term] +id: GO:1904005 +name: regulation of phospholipase D activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipase D activity." [GO_REF:0000059, GOC:TermGenie, PMID:11211872] +synonym: "regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0010517 ! regulation of phospholipase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004630 ! phospholipase D activity +relationship: regulates GO:0004630 ! phospholipase D activity +created_by: sl +creation_date: 2015-03-06T17:20:05Z + +[Term] +id: GO:1904006 +name: negative regulation of phospholipase D activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity." [GO_REF:0000059, GOC:TermGenie, PMID:11211872] +synonym: "down regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "down regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phospholipase D activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phospholipase D activity" EXACT [GOC:TermGenie] +synonym: "downregulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "downregulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phospholipase D activity" EXACT [GOC:TermGenie] +synonym: "inhibition of choline phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of lecithinase D activity" NARROW [GOC:TermGenie] +synonym: "inhibition of lipophosphodiesterase II activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylcholine phosphatidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phospholipase D activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0010519 ! negative regulation of phospholipase activity +is_a: GO:1904005 ! regulation of phospholipase D activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004630 ! phospholipase D activity +relationship: negatively_regulates GO:0004630 ! phospholipase D activity +created_by: sl +creation_date: 2015-03-06T17:20:11Z + +[Term] +id: GO:1904007 +name: positive regulation of phospholipase D activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipase D activity." [GO_REF:0000059, GOC:TermGenie, PMID:11211872] +synonym: "activation of choline phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of lecithinase D activity" NARROW [GOC:TermGenie] +synonym: "activation of lipophosphodiesterase II activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylcholine phosphatidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of phospholipase D activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "up regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phospholipase D activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phospholipase D activity" EXACT [GOC:TermGenie] +synonym: "upregulation of choline phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of lecithinase D activity" EXACT [GOC:TermGenie] +synonym: "upregulation of lipophosphodiesterase II activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylcholine phosphatidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phospholipase D activity" EXACT [GOC:TermGenie] +is_a: GO:0010518 ! positive regulation of phospholipase activity +is_a: GO:1904005 ! regulation of phospholipase D activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004630 ! phospholipase D activity +relationship: positively_regulates GO:0004630 ! phospholipase D activity +created_by: sl +creation_date: 2015-03-06T17:20:17Z + +[Term] +id: GO:1904008 +name: response to monosodium glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20704590] +is_a: GO:1902074 ! response to salt +created_by: sl +creation_date: 2015-03-06T18:26:34Z + +[Term] +id: GO:1904009 +name: cellular response to monosodium glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20704590] +is_a: GO:1902075 ! cellular response to salt +is_a: GO:1904008 ! response to monosodium glutamate +created_by: sl +creation_date: 2015-03-06T18:26:40Z + +[Term] +id: GO:1904010 +name: response to Aroclor 1254 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18602130] +is_a: GO:0009636 ! response to toxic substance +created_by: sl +creation_date: 2015-03-06T18:35:00Z + +[Term] +id: GO:1904011 +name: cellular response to Aroclor 1254 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18602130] +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1904010 ! response to Aroclor 1254 +created_by: sl +creation_date: 2015-03-06T18:35:06Z + +[Term] +id: GO:1904012 +name: obsolete platinum binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with platinum." [GO_REF:0000067, GOC:TermGenie, PMID:10089464] +comment: The reason for obsoletion is that binding to platinum does not have physiological relevance. +is_obsolete: true +created_by: sl +creation_date: 2015-03-06T19:07:37Z + +[Term] +id: GO:1904013 +name: obsolete xenon atom binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with xenon atom." [GO_REF:0000067, GOC:TermGenie, PMID:10089464] +comment: The reason for obsoletion is that binding to xenon does not have physiological relevance. +is_obsolete: true +created_by: sl +creation_date: 2015-03-06T19:07:43Z + +[Term] +id: GO:1904014 +name: response to serotonin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0071867 ! response to monoamine +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-03-06T19:33:54Z + +[Term] +id: GO:1904015 +name: cellular response to serotonin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071868 ! cellular response to monoamine stimulus +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904014 ! response to serotonin +created_by: sl +creation_date: 2015-03-06T19:34:00Z + +[Term] +id: GO:1904016 +name: response to Thyroglobulin triiodothyronine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:7531505] +is_a: GO:0010033 ! response to organic substance +created_by: sl +creation_date: 2015-03-06T19:34:07Z + +[Term] +id: GO:1904017 +name: cellular response to Thyroglobulin triiodothyronine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:7531505] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1904016 ! response to Thyroglobulin triiodothyronine +created_by: sl +creation_date: 2015-03-06T19:34:13Z + +[Term] +id: GO:1904018 +name: positive regulation of vasculature development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453] +synonym: "activation of vascular system development" RELATED [GOC:TermGenie] +synonym: "activation of vasculature development" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "up regulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular system development" RELATED [GOC:TermGenie] +synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001944 ! vasculature development +relationship: positively_regulates GO:0001944 ! vasculature development +created_by: sl +creation_date: 2015-03-06T22:17:04Z + +[Term] +id: GO:1904019 +name: epithelial cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015] +synonym: "epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: sl +creation_date: 2015-03-06T22:27:17Z + +[Term] +id: GO:1904020 +name: regulation of G protein-coupled receptor internalization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization." [GO_REF:0000058, GOC:TermGenie, PMID:24732013] +synonym: "regulation of G-protein-coupled receptor internalization" EXACT [] +is_a: GO:0002090 ! regulation of receptor internalization +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002031 ! G protein-coupled receptor internalization +relationship: regulates GO:0002031 ! G protein-coupled receptor internalization +created_by: pga +creation_date: 2015-03-10T17:10:45Z + +[Term] +id: GO:1904021 +name: negative regulation of G protein-coupled receptor internalization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization." [GO_REF:0000058, GOC:TermGenie, PMID:24732013] +synonym: "down regulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +synonym: "downregulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +synonym: "inhibition of G-protein coupled receptor internalization" NARROW [GOC:TermGenie] +synonym: "negative regulation of G-protein coupled receptor internalization" EXACT [] +is_a: GO:0002091 ! negative regulation of receptor internalization +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:1904020 ! regulation of G protein-coupled receptor internalization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002031 ! G protein-coupled receptor internalization +relationship: negatively_regulates GO:0002031 ! G protein-coupled receptor internalization +created_by: pga +creation_date: 2015-03-10T17:10:50Z + +[Term] +id: GO:1904022 +name: positive regulation of G protein-coupled receptor internalization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization." [GO_REF:0000058, GOC:TermGenie, PMID:24732013] +synonym: "activation of G-protein coupled receptor internalization" NARROW [GOC:TermGenie] +synonym: "positive regulation of G-protein coupled receptor internalization" EXACT [] +synonym: "up regulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +synonym: "upregulation of G-protein coupled receptor internalization" EXACT [GOC:TermGenie] +is_a: GO:0002092 ! positive regulation of receptor internalization +is_a: GO:1904020 ! regulation of G protein-coupled receptor internalization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002031 ! G protein-coupled receptor internalization +relationship: positively_regulates GO:0002031 ! G protein-coupled receptor internalization +created_by: pga +creation_date: 2015-03-10T17:10:56Z + +[Term] +id: GO:1904023 +name: regulation of glucose catabolic process to lactate via pyruvate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:20935145] +synonym: "regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "regulation of homolactic fermentation" EXACT [GOC:TermGenie] +is_a: GO:0010906 ! regulation of glucose metabolic process +is_a: GO:0043465 ! regulation of fermentation +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:1902688 ! regulation of NAD metabolic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +relationship: regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +created_by: dph +creation_date: 2015-03-11T16:57:32Z + +[Term] +id: GO:1904024 +name: negative regulation of glucose catabolic process to lactate via pyruvate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:20935145] +synonym: "down regulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "down regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "down regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "down regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "down regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "down regulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "down-regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "down-regulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "downregulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "downregulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "downregulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "downregulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "downregulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "inhibition of glucose catabolic process to lactate via pyruvate" NARROW [GOC:TermGenie] +synonym: "inhibition of glucose fermentation to lactate via pyruvate" NARROW [GOC:TermGenie] +synonym: "inhibition of homofermentation" NARROW [GOC:TermGenie] +synonym: "inhibition of homofermentative lactate fermentation" NARROW [GOC:TermGenie] +synonym: "inhibition of homofermentative pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of homolactate fermentation" NARROW [GOC:TermGenie] +synonym: "inhibition of homolactic fermentation" NARROW [GOC:TermGenie] +synonym: "negative regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "negative regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "negative regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "negative regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "negative regulation of homolactic fermentation" EXACT [GOC:TermGenie] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1901003 ! negative regulation of fermentation +is_a: GO:1902689 ! negative regulation of NAD metabolic process +is_a: GO:1903579 ! negative regulation of ATP metabolic process +is_a: GO:1904023 ! regulation of glucose catabolic process to lactate via pyruvate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +relationship: negatively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +created_by: dph +creation_date: 2015-03-11T16:57:38Z + +[Term] +id: GO:1904025 +name: positive regulation of glucose catabolic process to lactate via pyruvate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:20935145] +synonym: "activation of glucose catabolic process to lactate via pyruvate" NARROW [GOC:TermGenie] +synonym: "activation of glucose fermentation to lactate via pyruvate" NARROW [GOC:TermGenie] +synonym: "activation of homofermentation" NARROW [GOC:TermGenie] +synonym: "activation of homofermentative lactate fermentation" NARROW [GOC:TermGenie] +synonym: "activation of homofermentative pathway" NARROW [GOC:TermGenie] +synonym: "activation of homolactate fermentation" NARROW [GOC:TermGenie] +synonym: "activation of homolactic fermentation" NARROW [GOC:TermGenie] +synonym: "positive regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "positive regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "positive regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "positive regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "positive regulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "up regulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "up regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "up regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "up regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "up regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "up regulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "up-regulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "up-regulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "up-regulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "up-regulation of homolactic fermentation" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose catabolic process to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "upregulation of glucose fermentation to lactate via pyruvate" EXACT [GOC:TermGenie] +synonym: "upregulation of homofermentation" EXACT [GOC:TermGenie] +synonym: "upregulation of homofermentative lactate fermentation" EXACT [GOC:TermGenie] +synonym: "upregulation of homofermentative pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of homolactate fermentation" EXACT [GOC:TermGenie] +synonym: "upregulation of homolactic fermentation" EXACT [GOC:TermGenie] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0010907 ! positive regulation of glucose metabolic process +is_a: GO:1902690 ! positive regulation of NAD metabolic process +is_a: GO:1903580 ! positive regulation of ATP metabolic process +is_a: GO:1904023 ! regulation of glucose catabolic process to lactate via pyruvate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +relationship: positively_regulates GO:0019661 ! glucose catabolic process to lactate via pyruvate +created_by: dph +creation_date: 2015-03-11T16:57:44Z + +[Term] +id: GO:1904026 +name: regulation of collagen fibril organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] +synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "regulation of collagen fibrillogenesis" RELATED [] +synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +is_a: GO:1902903 ! regulation of supramolecular fiber organization +is_a: GO:1903053 ! regulation of extracellular matrix organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030199 ! collagen fibril organization +relationship: regulates GO:0030199 ! collagen fibril organization +created_by: ae +creation_date: 2015-03-12T12:36:52Z + +[Term] +id: GO:1904027 +name: negative regulation of collagen fibril organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] +synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "inhibition of collagen fibril organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of collagen fibril organization" NARROW [GOC:TermGenie] +synonym: "inhibition of fibrillar collagen organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +is_a: GO:1903054 ! negative regulation of extracellular matrix organization +is_a: GO:1904026 ! regulation of collagen fibril organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030199 ! collagen fibril organization +relationship: negatively_regulates GO:0030199 ! collagen fibril organization +created_by: ae +creation_date: 2015-03-12T12:36:59Z + +[Term] +id: GO:1904028 +name: positive regulation of collagen fibril organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] +synonym: "activation of collagen fibril organisation" NARROW [GOC:TermGenie] +synonym: "activation of collagen fibril organization" NARROW [GOC:TermGenie] +synonym: "activation of fibrillar collagen organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie] +synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +is_a: GO:1903055 ! positive regulation of extracellular matrix organization +is_a: GO:1904026 ! regulation of collagen fibril organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030199 ! collagen fibril organization +relationship: positively_regulates GO:0030199 ! collagen fibril organization +created_by: ae +creation_date: 2015-03-12T12:37:06Z + +[Term] +id: GO:1904029 +name: regulation of cyclin-dependent protein kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22995177] +is_a: GO:0045859 ! regulation of protein kinase activity +is_a: GO:0051726 ! regulation of cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097472 ! cyclin-dependent protein kinase activity +relationship: regulates GO:0097472 ! cyclin-dependent protein kinase activity +created_by: als +creation_date: 2015-03-13T15:43:38Z + +[Term] +id: GO:1904030 +name: negative regulation of cyclin-dependent protein kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22995177] +synonym: "down regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0006469 ! negative regulation of protein kinase activity +is_a: GO:1904029 ! regulation of cyclin-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097472 ! cyclin-dependent protein kinase activity +relationship: negatively_regulates GO:0097472 ! cyclin-dependent protein kinase activity +created_by: als +creation_date: 2015-03-13T15:43:44Z + +[Term] +id: GO:1904031 +name: positive regulation of cyclin-dependent protein kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22995177] +synonym: "activation of cyclin-dependent protein kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0045860 ! positive regulation of protein kinase activity +is_a: GO:1904029 ! regulation of cyclin-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097472 ! cyclin-dependent protein kinase activity +relationship: positively_regulates GO:0097472 ! cyclin-dependent protein kinase activity +created_by: als +creation_date: 2015-03-13T15:43:50Z + +[Term] +id: GO:1904032 +name: regulation of t-SNARE clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of t-SNARE clustering." [GO_REF:0000058, GOC:TermGenie, PMID:22528485] +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990656 ! t-SNARE clustering +relationship: regulates GO:1990656 ! t-SNARE clustering +created_by: sl +creation_date: 2015-03-13T21:21:38Z + +[Term] +id: GO:1904033 +name: negative regulation of t-SNARE clustering +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering." [GO_REF:0000058, GOC:TermGenie, PMID:22528485] +synonym: "down regulation of t-SNARE clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of t-SNARE clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of t-SNARE clustering" EXACT [GOC:TermGenie] +synonym: "inhibition of t-SNARE clustering" NARROW [GOC:TermGenie] +is_a: GO:1904032 ! regulation of t-SNARE clustering +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990656 ! t-SNARE clustering +relationship: negatively_regulates GO:1990656 ! t-SNARE clustering +created_by: sl +creation_date: 2015-03-13T21:21:44Z + +[Term] +id: GO:1904034 +name: positive regulation of t-SNARE clustering +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of t-SNARE clustering." [GO_REF:0000058, GOC:TermGenie, PMID:22528485] +synonym: "activation of t-SNARE clustering" NARROW [GOC:TermGenie] +synonym: "up regulation of t-SNARE clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of t-SNARE clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of t-SNARE clustering" EXACT [GOC:TermGenie] +is_a: GO:1904032 ! regulation of t-SNARE clustering +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990656 ! t-SNARE clustering +relationship: positively_regulates GO:1990656 ! t-SNARE clustering +created_by: sl +creation_date: 2015-03-13T21:21:50Z + +[Term] +id: GO:1904035 +name: regulation of epithelial cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] +synonym: "regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904019 ! epithelial cell apoptotic process +relationship: regulates GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2015-03-13T22:05:41Z + +[Term] +id: GO:1904036 +name: negative regulation of epithelial cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] +synonym: "down regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of epithelial cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904019 ! epithelial cell apoptotic process +relationship: negatively_regulates GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2015-03-13T22:05:47Z + +[Term] +id: GO:1904037 +name: positive regulation of epithelial cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] +synonym: "activation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of epithelial cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904019 ! epithelial cell apoptotic process +relationship: positively_regulates GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2015-03-13T22:05:53Z + +[Term] +id: GO:1904038 +name: regulation of iron export across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "regulation of ferrous iron export" NARROW [] +synonym: "regulation of iron(2+) export" NARROW [] +is_a: GO:0034759 ! regulation of iron ion transmembrane transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1903988 ! iron ion export across plasma membrane +relationship: regulates GO:1903988 ! iron ion export across plasma membrane +created_by: kom +creation_date: 2015-03-16T15:36:37Z + +[Term] +id: GO:1904039 +name: negative regulation of iron export across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "down regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "down regulation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "down-regulation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "downregulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "downregulation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "inhibition of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "negative regulation of iron(2+) export" NARROW [] +is_a: GO:0034760 ! negative regulation of iron ion transmembrane transport +is_a: GO:1904038 ! regulation of iron export across plasma membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1903988 ! iron ion export across plasma membrane +relationship: negatively_regulates GO:1903988 ! iron ion export across plasma membrane +created_by: kom +creation_date: 2015-03-16T15:36:43Z + +[Term] +id: GO:1904040 +name: positive regulation of iron export across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "activation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "activation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "positive regulation of iron(2+) export" NARROW [] +synonym: "up regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "up regulation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "up-regulation of iron(2+) export" NARROW [GOC:TermGenie] +synonym: "upregulation of ferrous iron export" NARROW [GOC:TermGenie] +synonym: "upregulation of iron(2+) export" NARROW [GOC:TermGenie] +is_a: GO:0034761 ! positive regulation of iron ion transmembrane transport +is_a: GO:1904038 ! regulation of iron export across plasma membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1903988 ! iron ion export across plasma membrane +relationship: positively_regulates GO:1903988 ! iron ion export across plasma membrane +created_by: kom +creation_date: 2015-03-16T15:36:49Z + +[Term] +id: GO:1904041 +name: regulation of cystathionine beta-synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity." [GO_REF:0000059, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24416422] +synonym: "regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004122 ! cystathionine beta-synthase activity +relationship: regulates GO:0004122 ! cystathionine beta-synthase activity +created_by: hal +creation_date: 2015-03-16T15:52:41Z + +[Term] +id: GO:1904042 +name: negative regulation of cystathionine beta-synthase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity." [GO_REF:0000059, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24416422] +synonym: "down regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of beta-thionase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cystathionine beta-synthase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of L-serine hydro-lyase (adding homocysteine)" NARROW [GOC:TermGenie] +synonym: "inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of methylcysteine synthase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of serine sulfhydrase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of serine sulfhydrylase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051350 ! negative regulation of lyase activity +is_a: GO:1904041 ! regulation of cystathionine beta-synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004122 ! cystathionine beta-synthase activity +relationship: negatively_regulates GO:0004122 ! cystathionine beta-synthase activity +created_by: hal +creation_date: 2015-03-16T15:52:47Z + +[Term] +id: GO:1904043 +name: positive regulation of cystathionine beta-synthase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity." [GO_REF:0000059, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24416422] +synonym: "activation of beta-thionase activity" NARROW [GOC:TermGenie] +synonym: "activation of cystathionine beta-synthase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-serine hydro-lyase (adding homocysteine)" NARROW [GOC:TermGenie] +synonym: "activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" NARROW [GOC:TermGenie] +synonym: "activation of methylcysteine synthase activity" NARROW [GOC:TermGenie] +synonym: "activation of serine sulfhydrase activity" NARROW [GOC:TermGenie] +synonym: "activation of serine sulfhydrylase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-thionase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] +synonym: "upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] +is_a: GO:0051349 ! positive regulation of lyase activity +is_a: GO:1904041 ! regulation of cystathionine beta-synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004122 ! cystathionine beta-synthase activity +relationship: positively_regulates GO:0004122 ! cystathionine beta-synthase activity +created_by: hal +creation_date: 2015-03-16T15:52:53Z + +[Term] +id: GO:1904044 +name: response to aldosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17644563] +is_a: GO:0051385 ! response to mineralocorticoid +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-03-16T23:07:53Z + +[Term] +id: GO:1904045 +name: cellular response to aldosterone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17644563] +is_a: GO:0071389 ! cellular response to mineralocorticoid stimulus +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:0110096 ! cellular response to aldehyde +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904044 ! response to aldosterone +created_by: sl +creation_date: 2015-03-16T23:07:59Z + +[Term] +id: GO:1904046 +name: negative regulation of vascular endothelial growth factor production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production." [GO_REF:0000058, GOC:TermGenie, PMID:19404486] +synonym: "down regulation of vascular endothelial growth factor production" EXACT [GOC:TermGenie] +synonym: "down regulation of VEGF production" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular endothelial growth factor production" EXACT [GOC:TermGenie] +synonym: "down-regulation of VEGF production" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular endothelial growth factor production" EXACT [GOC:TermGenie] +synonym: "downregulation of VEGF production" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular endothelial growth factor production" NARROW [GOC:TermGenie] +synonym: "inhibition of VEGF production" NARROW [GOC:TermGenie] +synonym: "negative regulation of VEGF production" EXACT [GOC:TermGenie] +is_a: GO:0001818 ! negative regulation of cytokine production +is_a: GO:0010574 ! regulation of vascular endothelial growth factor production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010573 ! vascular endothelial growth factor production +relationship: negatively_regulates GO:0010573 ! vascular endothelial growth factor production +created_by: sl +creation_date: 2015-03-16T23:27:06Z + +[Term] +id: GO:1904047 +name: S-adenosyl-L-methionine binding +namespace: molecular_function +alt_id: GO:0070283 +def: "Interacting selectively and non-covalently with S-adenosyl-L-methionine." [GO_REF:0000067, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:22985361] +synonym: "radical SAM enzyme activity" NARROW [] +xref: Reactome:R-HSA-947535 "Cyclisation of GTP to precursor Z" +is_a: GO:0008144 ! drug binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:1901681 ! sulfur compound binding +created_by: hal +creation_date: 2015-03-17T10:32:16Z + +[Term] +id: GO:1904048 +name: regulation of spontaneous neurotransmitter secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22314364] +comment: An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype). +synonym: "regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0150003 ! regulation of spontaneous synaptic transmission +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061669 ! spontaneous neurotransmitter secretion +relationship: regulates GO:0061669 ! spontaneous neurotransmitter secretion +created_by: pad +creation_date: 2015-03-17T10:37:11Z + +[Term] +id: GO:1904049 +name: negative regulation of spontaneous neurotransmitter secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22314364] +comment: An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype). +synonym: "down regulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of spontaneous neurotransmitter secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of stimulus-independent neurotransmitter secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:1904048 ! regulation of spontaneous neurotransmitter secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061669 ! spontaneous neurotransmitter secretion +relationship: negatively_regulates GO:0061669 ! spontaneous neurotransmitter secretion +created_by: pad +creation_date: 2015-03-17T10:37:17Z + +[Term] +id: GO:1904050 +name: positive regulation of spontaneous neurotransmitter secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22314364] +comment: An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype). +synonym: "activation of spontaneous neurotransmitter secretion" NARROW [GOC:TermGenie] +synonym: "activation of stimulus-independent neurotransmitter secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of spontaneous neurotransmitter secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of stimulus-independent neurotransmitter secretion" EXACT [GOC:TermGenie] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:1904048 ! regulation of spontaneous neurotransmitter secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061669 ! spontaneous neurotransmitter secretion +relationship: positively_regulates GO:0061669 ! spontaneous neurotransmitter secretion +created_by: pad +creation_date: 2015-03-17T10:37:23Z + +[Term] +id: GO:1904051 +name: regulation of protein targeting to vacuole involved in autophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype). +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:1903335 ! regulation of vacuolar transport +is_a: GO:1903533 ! regulation of protein targeting +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +relationship: regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +created_by: pad +creation_date: 2015-03-17T13:54:16Z + +[Term] +id: GO:1904052 +name: negative regulation of protein targeting to vacuole involved in autophagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype). +synonym: "down regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +synonym: "inhibition of protein targeting to vacuole involved in autophagy" NARROW [GOC:TermGenie] +is_a: GO:0010507 ! negative regulation of autophagy +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1903336 ! negative regulation of vacuolar transport +is_a: GO:1904051 ! regulation of protein targeting to vacuole involved in autophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +relationship: negatively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +created_by: pad +creation_date: 2015-03-17T13:54:22Z + +[Term] +id: GO:1904053 +name: positive regulation of protein targeting to vacuole involved in autophagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +comment: An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype). +synonym: "activation of protein targeting to vacuole involved in autophagy" NARROW [GOC:TermGenie] +synonym: "up regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of protein targeting to vacuole involved in autophagy" EXACT [GOC:TermGenie] +is_a: GO:0010508 ! positive regulation of autophagy +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1903337 ! positive regulation of vacuolar transport +is_a: GO:1904051 ! regulation of protein targeting to vacuole involved in autophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +relationship: positively_regulates GO:0071211 ! protein targeting to vacuole involved in autophagy +created_by: pad +creation_date: 2015-03-17T13:54:27Z + +[Term] +id: GO:1904054 +name: regulation of cholangiocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] +synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990705 ! cholangiocyte proliferation +relationship: regulates GO:1990705 ! cholangiocyte proliferation +created_by: sl +creation_date: 2015-03-18T17:56:14Z + +[Term] +id: GO:1904055 +name: negative regulation of cholangiocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] +synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of cholangiocyte proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of hepatoblast proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:1904054 ! regulation of cholangiocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990705 ! cholangiocyte proliferation +relationship: negatively_regulates GO:1990705 ! cholangiocyte proliferation +created_by: sl +creation_date: 2015-03-18T17:56:20Z + +[Term] +id: GO:1904056 +name: positive regulation of cholangiocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] +synonym: "activation of cholangiocyte proliferation" NARROW [GOC:TermGenie] +synonym: "activation of hepatoblast proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:1904054 ! regulation of cholangiocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990705 ! cholangiocyte proliferation +relationship: positively_regulates GO:1990705 ! cholangiocyte proliferation +created_by: sl +creation_date: 2015-03-18T17:56:26Z + +[Term] +id: GO:1904057 +name: negative regulation of sensory perception of pain +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] +synonym: "down regulation of nociception" EXACT [GOC:TermGenie] +synonym: "down regulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie] +synonym: "down-regulation of nociception" EXACT [GOC:TermGenie] +synonym: "down-regulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie] +synonym: "downregulation of nociception" EXACT [GOC:TermGenie] +synonym: "downregulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie] +synonym: "inhibition of nociception" NARROW [GOC:TermGenie] +synonym: "inhibition of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory perception of pain" NARROW [GOC:TermGenie] +synonym: "negative regulation of nociception" EXACT [GOC:TermGenie] +synonym: "negative regulation of perception of physiological pain" NARROW [GOC:TermGenie] +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0051930 ! regulation of sensory perception of pain +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019233 ! sensory perception of pain +relationship: negatively_regulates GO:0019233 ! sensory perception of pain +created_by: sl +creation_date: 2015-03-18T20:33:57Z + +[Term] +id: GO:1904058 +name: positive regulation of sensory perception of pain +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] +synonym: "activation of nociception" NARROW [GOC:TermGenie] +synonym: "activation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "activation of sensory perception of pain" NARROW [GOC:TermGenie] +synonym: "positive regulation of nociception" EXACT [GOC:TermGenie] +synonym: "positive regulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "up regulation of nociception" EXACT [GOC:TermGenie] +synonym: "up regulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie] +synonym: "up-regulation of nociception" EXACT [GOC:TermGenie] +synonym: "up-regulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie] +synonym: "upregulation of nociception" EXACT [GOC:TermGenie] +synonym: "upregulation of perception of physiological pain" NARROW [GOC:TermGenie] +synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie] +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0051930 ! regulation of sensory perception of pain +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019233 ! sensory perception of pain +relationship: positively_regulates GO:0019233 ! sensory perception of pain +created_by: sl +creation_date: 2015-03-18T20:34:03Z + +[Term] +id: GO:1904059 +name: regulation of locomotor rhythm +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of locomotor rhythm." [GO_REF:0000058, GOC:TermGenie, PMID:16310969] +synonym: "regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +is_a: GO:0042752 ! regulation of circadian rhythm +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045475 ! locomotor rhythm +relationship: regulates GO:0045475 ! locomotor rhythm +created_by: sl +creation_date: 2015-03-18T20:38:52Z + +[Term] +id: GO:1904060 +name: negative regulation of locomotor rhythm +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm." [GO_REF:0000058, GOC:TermGenie, PMID:16310969] +synonym: "down regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "down regulation of locomotor rhythm" EXACT [GOC:TermGenie] +synonym: "down-regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "down-regulation of locomotor rhythm" EXACT [GOC:TermGenie] +synonym: "downregulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "downregulation of locomotor rhythm" EXACT [GOC:TermGenie] +synonym: "inhibition of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "inhibition of locomotor rhythm" NARROW [GOC:TermGenie] +synonym: "negative regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +is_a: GO:0042754 ! negative regulation of circadian rhythm +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:1904059 ! regulation of locomotor rhythm +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045475 ! locomotor rhythm +relationship: negatively_regulates GO:0045475 ! locomotor rhythm +created_by: sl +creation_date: 2015-03-18T20:38:58Z + +[Term] +id: GO:1904061 +name: positive regulation of locomotor rhythm +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of locomotor rhythm." [GO_REF:0000058, GOC:TermGenie, PMID:16310969] +synonym: "activation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "activation of locomotor rhythm" NARROW [GOC:TermGenie] +synonym: "positive regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "up regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "up regulation of locomotor rhythm" EXACT [GOC:TermGenie] +synonym: "up-regulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "up-regulation of locomotor rhythm" EXACT [GOC:TermGenie] +synonym: "upregulation of circadian locomotor activity rhythm" NARROW [GOC:TermGenie] +synonym: "upregulation of locomotor rhythm" EXACT [GOC:TermGenie] +is_a: GO:0042753 ! positive regulation of circadian rhythm +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:1904059 ! regulation of locomotor rhythm +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045475 ! locomotor rhythm +relationship: positively_regulates GO:0045475 ! locomotor rhythm +created_by: sl +creation_date: 2015-03-18T20:39:03Z + +[Term] +id: GO:1904062 +name: regulation of cation transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] +is_a: GO:0034765 ! regulation of ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098655 ! cation transmembrane transport +relationship: regulates GO:0098655 ! cation transmembrane transport +created_by: sl +creation_date: 2015-03-18T21:11:43Z + +[Term] +id: GO:1904063 +name: negative regulation of cation transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] +synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie] +is_a: GO:0034766 ! negative regulation of ion transmembrane transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098655 ! cation transmembrane transport +relationship: negatively_regulates GO:0098655 ! cation transmembrane transport +created_by: sl +creation_date: 2015-03-18T21:11:50Z + +[Term] +id: GO:1904064 +name: positive regulation of cation transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] +synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie] +synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:0034767 ! positive regulation of ion transmembrane transport +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098655 ! cation transmembrane transport +relationship: positively_regulates GO:0098655 ! cation transmembrane transport +created_by: sl +creation_date: 2015-03-18T21:11:55Z + +[Term] +id: GO:1904065 +name: G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission +namespace: biological_process +def: "Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, pmid:22588719] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission" EXACT [] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion" NARROW [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion" EXACT [GOC:TermGenie] +synonym: "muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion" EXACT [GOC:TermGenie] +is_a: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway +intersection_of: GO:0007213 ! G protein-coupled acetylcholine receptor signaling pathway +intersection_of: part_of GO:0014057 ! positive regulation of acetylcholine secretion, neurotransmission +relationship: part_of GO:0014057 ! positive regulation of acetylcholine secretion, neurotransmission +created_by: kmv +creation_date: 2015-03-19T15:28:47Z + +[Term] +id: GO:1904066 +name: G protein-coupled receptor signaling pathway involved in dauer larval development +namespace: biological_process +def: "Any G protein-coupled receptor signaling pathway that is involved in dauer larval development." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, pmid:22665789] +synonym: "G protein coupled receptor protein signaling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in dauer larval development" EXACT [GOC:TermGenie] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: part_of GO:0040024 ! dauer larval development +relationship: part_of GO:0040024 ! dauer larval development +created_by: kmv +creation_date: 2015-03-20T00:51:06Z + +[Term] +id: GO:1904067 +name: ascr#2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ascr#2." [GO_REF:0000067, GOC:kmv, GOC:TermGenie, PMID:22665789] +is_a: GO:0005550 ! pheromone binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: kmv +creation_date: 2015-03-20T01:39:04Z + +[Term] +id: GO:1904068 +name: G protein-coupled receptor signaling pathway involved in social behavior +namespace: biological_process +def: "Any G protein-coupled receptor signaling pathway that is involved in social behavior." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, pmid:22665789] +synonym: "G protein coupled receptor protein signaling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signaling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G protein coupled receptor protein signalling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signal transduction involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor protein signaling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor signaling pathway involved in social behavior" EXACT [] +synonym: "G-protein coupled receptor signaling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G-protein coupled receptor signalling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signaling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "G-protein-coupled receptor protein signalling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "GPCR signaling pathway involved in social behaviour" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in cooperative behavior" RELATED [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in social behavior" EXACT [GOC:TermGenie] +synonym: "GPCR signalling pathway involved in social behaviour" EXACT [GOC:TermGenie] +is_a: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: GO:0007186 ! G protein-coupled receptor signaling pathway +intersection_of: part_of GO:0035176 ! social behavior +relationship: part_of GO:0035176 ! social behavior +created_by: kmv +creation_date: 2015-03-20T01:51:10Z + +[Term] +id: GO:1904069 +name: ascaroside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ascaroside." [GO_REF:0000068, GOC:kmv, GOC:TermGenie, pmid:25775534] +synonym: "ascaroside metabolism" EXACT [GOC:TermGenie] +is_a: GO:0016137 ! glycoside metabolic process +created_by: kmv +creation_date: 2015-03-20T02:40:14Z + +[Term] +id: GO:1904070 +name: ascaroside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ascaroside." [GO_REF:0000068, GOC:kmv, GOC:TermGenie, pmid:25775534] +synonym: "ascaroside anabolism" EXACT [GOC:TermGenie] +synonym: "ascaroside biosynthesis" EXACT [GOC:TermGenie] +synonym: "ascaroside formation" EXACT [GOC:TermGenie] +synonym: "ascaroside synthesis" EXACT [GOC:TermGenie] +is_a: GO:0016138 ! glycoside biosynthetic process +is_a: GO:1904069 ! ascaroside metabolic process +created_by: kmv +creation_date: 2015-03-20T02:40:20Z + +[Term] +id: GO:1904071 +name: presynaptic active zone assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix." [GO_REF:0000079, GOC:pr, GOC:TermGenie, PMID:10769383] +synonym: "pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "presynaptic active zone formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:1990709 ! presynaptic active zone organization +relationship: part_of GO:0099054 ! presynapse assembly +created_by: pr +creation_date: 2015-03-20T10:36:27Z + +[Term] +id: GO:1904072 +name: presynaptic active zone disassembly +namespace: biological_process +def: "The disaggregation of a presynaptic active zone into its constituent components." [GO_REF:0000079, GOC:pr, GOC:TermGenie, ISBN:9780387325606] +synonym: "pre-synaptic active zone component disassembly" NARROW [GOC:TermGenie] +synonym: "pre-synaptic active zone disassembly" EXACT [GOC:TermGenie] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:1990709 ! presynaptic active zone organization +created_by: pr +creation_date: 2015-03-20T10:36:33Z + +[Term] +id: GO:1904073 +name: regulation of trophectodermal cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] +synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0120222 ! regulation of blastocyst development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001834 ! trophectodermal cell proliferation +relationship: regulates GO:0001834 ! trophectodermal cell proliferation +created_by: tb +creation_date: 2015-03-20T16:55:56Z + +[Term] +id: GO:1904074 +name: negative regulation of trophectodermal cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] +synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of trophectoderm cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of trophectodermal cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1904073 ! regulation of trophectodermal cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001834 ! trophectodermal cell proliferation +relationship: negatively_regulates GO:0001834 ! trophectodermal cell proliferation +created_by: tb +creation_date: 2015-03-20T16:56:02Z + +[Term] +id: GO:1904075 +name: positive regulation of trophectodermal cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] +synonym: "activation of trophectoderm cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of trophectodermal cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1904073 ! regulation of trophectodermal cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001834 ! trophectodermal cell proliferation +relationship: positively_regulates GO:0001834 ! trophectodermal cell proliferation +created_by: tb +creation_date: 2015-03-20T16:56:08Z + +[Term] +id: GO:1904076 +name: regulation of estrogen biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of estrogen biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24530842] +synonym: "regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006703 ! estrogen biosynthetic process +relationship: regulates GO:0006703 ! estrogen biosynthetic process +created_by: tb +creation_date: 2015-03-20T16:56:14Z + +[Term] +id: GO:1904077 +name: negative regulation of estrogen biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24530842] +synonym: "down regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "down regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "downregulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of estrogen anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of estrogen biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of estrogen biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of estrogen formation" NARROW [GOC:TermGenie] +synonym: "inhibition of estrogen synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of oestrogen biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of oestrogen biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:1904076 ! regulation of estrogen biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006703 ! estrogen biosynthetic process +relationship: negatively_regulates GO:0006703 ! estrogen biosynthetic process +created_by: tb +creation_date: 2015-03-20T16:56:20Z + +[Term] +id: GO:1904078 +name: positive regulation of estrogen biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24530842] +synonym: "activation of estrogen anabolism" NARROW [GOC:TermGenie] +synonym: "activation of estrogen biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of estrogen biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of estrogen formation" NARROW [GOC:TermGenie] +synonym: "activation of estrogen synthesis" NARROW [GOC:TermGenie] +synonym: "activation of oestrogen biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of oestrogen biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "up regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of estrogen anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of estrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of estrogen biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of estrogen formation" EXACT [GOC:TermGenie] +synonym: "upregulation of estrogen synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of oestrogen biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of oestrogen biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:1904076 ! regulation of estrogen biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006703 ! estrogen biosynthetic process +relationship: positively_regulates GO:0006703 ! estrogen biosynthetic process +created_by: tb +creation_date: 2015-03-20T16:56:26Z + +[Term] +id: GO:1904079 +name: obsolete negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process +namespace: biological_process +def: "OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in negative regulation of neuron apoptotic process." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:20150917] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "negative regulation of global transcription from Pol II promoter involved in neuron survival" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from Pol II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process" EXACT [] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in neuron survival" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in down regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in down-regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in downregulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in inhibition of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptotic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of programmed cell death, neurons" RELATED [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in neuron survival" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: kmv +creation_date: 2015-03-24T17:28:41Z + +[Term] +id: GO:1904080 +name: positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:11959845] +synonym: "activation of global transcription from RNA polymerase II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in neuron fate specification" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in neuron fate specification" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in neuron fate specification" EXACT [GOC:TermGenie] +is_a: GO:0060850 ! regulation of transcription involved in cell fate commitment +is_a: GO:1904081 ! positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0048665 ! neuron fate specification +relationship: part_of GO:0048665 ! neuron fate specification +created_by: kmv +creation_date: 2015-03-24T18:56:50Z + +[Term] +id: GO:1904081 +name: positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation." [GO_REF:0000060, GOC:kmv, GOC:TermGenie, PMID:24353061] +synonym: "activation of global transcription from RNA polymerase II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in neuron differentiation" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in neuron differentiation" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0030182 ! neuron differentiation +relationship: part_of GO:0030182 ! neuron differentiation +created_by: kmv +creation_date: 2015-03-24T20:15:59Z + +[Term] +id: GO:1904082 +name: pyrimidine nucleobase transmembrane transport +namespace: biological_process +def: "The process in which pyrimidine is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] +is_a: GO:0015855 ! pyrimidine nucleobase transport +is_a: GO:0072531 ! pyrimidine-containing compound transmembrane transport +created_by: tb +creation_date: 2015-03-25T00:13:16Z + +[Term] +id: GO:1904083 +name: obsolete regulation of epiboly +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of epiboly." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of epiboly" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2015-03-25T10:53:34Z + +[Term] +id: GO:1904084 +name: obsolete negative regulation of epiboly +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of epiboly" EXACT [GOC:TermGenie] +synonym: "down-regulation of epiboly" EXACT [GOC:TermGenie] +synonym: "downregulation of epiboly" EXACT [GOC:TermGenie] +synonym: "inhibition of epiboly" NARROW [GOC:TermGenie] +synonym: "negative regulation of epiboly" EXACT [] +is_obsolete: true +created_by: dos +creation_date: 2015-03-25T10:53:40Z + +[Term] +id: GO:1904085 +name: obsolete positive regulation of epiboly +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of epiboly." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of epiboly" NARROW [GOC:TermGenie] +synonym: "positive regulation of epiboly" EXACT [] +synonym: "up regulation of epiboly" EXACT [GOC:TermGenie] +synonym: "up-regulation of epiboly" EXACT [GOC:TermGenie] +synonym: "upregulation of epiboly" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2015-03-25T10:53:47Z + +[Term] +id: GO:1904086 +name: regulation of epiboly involved in gastrulation with mouth forming second +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +relationship: regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +created_by: dos +creation_date: 2015-03-25T11:17:34Z + +[Term] +id: GO:1904087 +name: negative regulation of epiboly involved in gastrulation with mouth forming second +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +synonym: "down-regulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +synonym: "downregulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +synonym: "inhibition of epiboly involved in gastrulation with mouth forming second" NARROW [GOC:TermGenie] +is_a: GO:1904086 ! regulation of epiboly involved in gastrulation with mouth forming second +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +relationship: negatively_regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +created_by: dos +creation_date: 2015-03-25T11:17:41Z + +[Term] +id: GO:1904088 +name: positive regulation of epiboly involved in gastrulation with mouth forming second +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second." [GO_REF:0000058, GOC:TermGenie, PMID:24892953] +synonym: "activation of epiboly involved in gastrulation with mouth forming second" NARROW [GOC:TermGenie] +synonym: "up regulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +synonym: "up-regulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +synonym: "upregulation of epiboly involved in gastrulation with mouth forming second" EXACT [GOC:TermGenie] +is_a: GO:1904086 ! regulation of epiboly involved in gastrulation with mouth forming second +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +relationship: positively_regulates GO:0055113 ! epiboly involved in gastrulation with mouth forming second +created_by: dos +creation_date: 2015-03-25T11:17:47Z + +[Term] +id: GO:1904089 +name: negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process." [GO_REF:0000063, GOC:kmv, GOC:TermGenie, PMID:20150917] +synonym: "negative regulation of neuron apoptosis by negative regulation of transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of programmed cell death, neurons by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0051402 ! neuron apoptotic process +created_by: pr +creation_date: 2015-03-25T21:04:51Z + +[Term] +id: GO:1904090 +name: peptidase inhibitor complex +namespace: cellular_component +def: "A protein complex which is capable of peptidase inhibitor activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:20860624] +comment: An example of this is Cystatin-A in human (UniProt symbol P01040) in PMID:20860624 (inferred from physical interaction). +synonym: "Cathepsin-B - cystatin-A complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2015-03-26T10:16:27Z + +[Term] +id: GO:1904091 +name: peptidyl carrier protein activity +namespace: molecular_function +def: "Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process." [GO_REF:0000061, GOC:pr, GOC:TermGenie, GOC:vw, PMID:17502372] +comment: Examples are the ferrichrome synthetase Sib1 in S. pombe and the peptidyl carrier protein (PCP) module in bacterial nonribosomal peptide synthases (NRPSs), which holds the peptidyl group and acts as a swinging arm, limiting diffusion until the peptide comes into contact with the next enzymatic module in the NRPS process. +synonym: "Oligopeptid binding involved in non-ribosomal peptide biosynthesis" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in non-ribosomal peptide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in non-ribosomal peptide formation" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in non-ribosomal peptide synthesis" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide anabolism" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide biosynthesis" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide formation" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide synthesis" RELATED [GOC:TermGenie] +synonym: "Oligopeptid binding involved in nonribosomal peptide synthetase" RELATED [GOC:TermGenie] +synonym: "oligopeptide binding involved in non-ribosomal peptide biosynthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in non-ribosomal peptide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in non-ribosomal peptide formation" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in non-ribosomal peptide synthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in nonribosomal peptide anabolism" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in nonribosomal peptide biosynthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in nonribosomal peptide biosynthetic process" EXACT [GOC:pr] +synonym: "oligopeptide binding involved in nonribosomal peptide formation" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in nonribosomal peptide synthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptide binding involved in nonribosomal peptide synthetase" RELATED [GOC:TermGenie] +synonym: "oligopeptides binding involved in non-ribosomal peptide biosynthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in non-ribosomal peptide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in non-ribosomal peptide formation" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in non-ribosomal peptide synthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide anabolism" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide biosynthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide formation" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide synthesis" EXACT [GOC:TermGenie] +synonym: "oligopeptides binding involved in nonribosomal peptide synthetase" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in non-ribosomal peptide biosynthesis" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in non-ribosomal peptide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in non-ribosomal peptide formation" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in non-ribosomal peptide synthesis" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide anabolism" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide biosynthesis" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide biosynthetic process" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide formation" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide synthesis" RELATED [GOC:TermGenie] +synonym: "oligopeptido binding involved in nonribosomal peptide synthetase" RELATED [GOC:TermGenie] +synonym: "PCP" RELATED [] +synonym: "peptidyl binding involved in nonribosomal peptide biosynthesis" EXACT [GOC:pr] +synonym: "peptidyl binding involved in nonribosomal peptide biosynthetic process" EXACT [GOC:pr] +synonym: "peptidyl carrier protein" RELATED [GOC:pr] +synonym: "peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis" EXACT [] +synonym: "peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process" EXACT [GOC:pr] +is_a: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: GO:0140414 ! phosphopantetheine-dependent carrier activity +intersection_of: part_of GO:0019184 ! nonribosomal peptide biosynthetic process +relationship: part_of GO:0019184 ! nonribosomal peptide biosynthetic process +created_by: pr +creation_date: 2015-03-26T10:41:52Z + +[Term] +id: GO:1904092 +name: regulation of autophagic cell death +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of autophagic cell death." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25736836] +synonym: "regulation of autophagic death" BROAD [GOC:TermGenie] +synonym: "regulation of programmed cell death by autophagy" BROAD [GOC:TermGenie] +synonym: "regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "regulation of type II programmed cell death" RELATED [GOC:TermGenie] +is_a: GO:0043067 ! regulation of programmed cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048102 ! autophagic cell death +relationship: regulates GO:0048102 ! autophagic cell death +created_by: bhm +creation_date: 2015-03-26T16:41:32Z + +[Term] +id: GO:1904093 +name: negative regulation of autophagic cell death +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25736836] +synonym: "down regulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "down regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "down regulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "down-regulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "down-regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "downregulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "downregulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "inhibition of autophagic cell death" NARROW [GOC:TermGenie] +synonym: "inhibition of programmed cell death by macroautophagy" NARROW [GOC:TermGenie] +synonym: "inhibition of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "negative regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "negative regulation of type II programmed cell death" RELATED [GOC:TermGenie] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:1904092 ! regulation of autophagic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048102 ! autophagic cell death +relationship: negatively_regulates GO:0048102 ! autophagic cell death +created_by: bhm +creation_date: 2015-03-26T16:41:39Z + +[Term] +id: GO:1904094 +name: positive regulation of autophagic cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of autophagic cell death." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25736836] +synonym: "activation of autophagic cell death" NARROW [GOC:TermGenie] +synonym: "activation of programmed cell death by macroautophagy" NARROW [GOC:TermGenie] +synonym: "activation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "positive regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "positive regulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "up regulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "up regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "up regulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "up-regulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "up-regulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of type II programmed cell death" RELATED [GOC:TermGenie] +synonym: "upregulation of autophagic cell death" EXACT [GOC:TermGenie] +synonym: "upregulation of programmed cell death by macroautophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of type II programmed cell death" RELATED [GOC:TermGenie] +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:1904092 ! regulation of autophagic cell death +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048102 ! autophagic cell death +relationship: positively_regulates GO:0048102 ! autophagic cell death +created_by: bhm +creation_date: 2015-03-26T16:41:45Z + +[Term] +id: GO:1904095 +name: negative regulation of endosperm development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development." [GO_REF:0000058, GOC:TermGenie, PMID:25194028] +synonym: "down regulation of endosperm development" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosperm development" EXACT [GOC:TermGenie] +synonym: "downregulation of endosperm development" EXACT [GOC:TermGenie] +synonym: "inhibition of endosperm development" NARROW [GOC:TermGenie] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:2000014 ! regulation of endosperm development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009960 ! endosperm development +relationship: negatively_regulates GO:0009960 ! endosperm development +created_by: tb +creation_date: 2015-03-26T22:07:25Z + +[Term] +id: GO:1904096 +name: protein tyrosine phosphatase complex +namespace: cellular_component +def: "A protein complex which is capable of protein tyrosine phosphatase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:22389722] +comment: An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction). +is_a: GO:1903293 ! phosphatase complex +created_by: bhm +creation_date: 2015-03-27T14:34:59Z + +[Term] +id: GO:1904097 +name: acid phosphatase complex +namespace: cellular_component +def: "A protein complex which is capable of acid phosphatase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:8132635] +comment: An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction). +is_a: GO:1903293 ! phosphatase complex +created_by: bhm +creation_date: 2015-03-27T14:36:36Z + +[Term] +id: GO:1904098 +name: regulation of protein O-linked glycosylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] +synonym: "regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +is_a: GO:0060049 ! regulation of protein glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006493 ! protein O-linked glycosylation +relationship: regulates GO:0006493 ! protein O-linked glycosylation +created_by: krc +creation_date: 2015-03-27T16:09:58Z + +[Term] +id: GO:1904099 +name: negative regulation of protein O-linked glycosylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] +synonym: "down regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein amino acid O-linked glycosylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein O-linked glycosylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +is_a: GO:0060051 ! negative regulation of protein glycosylation +is_a: GO:1904098 ! regulation of protein O-linked glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006493 ! protein O-linked glycosylation +relationship: negatively_regulates GO:0006493 ! protein O-linked glycosylation +created_by: krc +creation_date: 2015-03-27T16:10:04Z + +[Term] +id: GO:1904100 +name: positive regulation of protein O-linked glycosylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] +synonym: "activation of protein amino acid O-linked glycosylation" NARROW [GOC:TermGenie] +synonym: "activation of protein O-linked glycosylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] +is_a: GO:0060050 ! positive regulation of protein glycosylation +is_a: GO:1904098 ! regulation of protein O-linked glycosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006493 ! protein O-linked glycosylation +relationship: positively_regulates GO:0006493 ! protein O-linked glycosylation +created_by: krc +creation_date: 2015-03-27T16:10:10Z + +[Term] +id: GO:1904101 +name: response to acadesine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:20802119] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0061478 ! response to platelet aggregation inhibitor +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mr +creation_date: 2015-03-30T22:36:26Z + +[Term] +id: GO:1904102 +name: cellular response to acadesine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:20802119] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904101 ! response to acadesine +created_by: mr +creation_date: 2015-03-30T22:36:32Z + +[Term] +id: GO:1904103 +name: regulation of convergent extension involved in gastrulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060027 ! convergent extension involved in gastrulation +relationship: regulates GO:0060027 ! convergent extension involved in gastrulation +created_by: dph +creation_date: 2015-04-01T11:17:05Z + +[Term] +id: GO:1904104 +name: negative regulation of convergent extension involved in gastrulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in gastrulation" NARROW [GOC:TermGenie] +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060027 ! convergent extension involved in gastrulation +relationship: negatively_regulates GO:0060027 ! convergent extension involved in gastrulation +created_by: dph +creation_date: 2015-04-01T11:17:12Z + +[Term] +id: GO:1904105 +name: positive regulation of convergent extension involved in gastrulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "activation of convergent extension involved in gastrulation" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in gastrulation" EXACT [GOC:TermGenie] +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060027 ! convergent extension involved in gastrulation +relationship: positively_regulates GO:0060027 ! convergent extension involved in gastrulation +created_by: dph +creation_date: 2015-04-01T11:17:18Z + +[Term] +id: GO:1904106 +name: protein localization to microvillus +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] +synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie] +synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie] +synonym: "protein localization in microvillus" EXACT [GOC:TermGenie] +is_a: GO:0008104 ! protein localization +created_by: kmv +creation_date: 2015-04-01T18:14:41Z + +[Term] +id: GO:1904107 +name: protein localization to microvillus membrane +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a microvillus membrane." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] +synonym: "protein localisation in microvillus membrane" EXACT [GOC:TermGenie] +synonym: "protein localisation to microvillus membrane" EXACT [GOC:TermGenie] +synonym: "protein localization in microvillus membrane" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:1904106 ! protein localization to microvillus +is_a: GO:1990778 ! protein localization to cell periphery +created_by: kmv +creation_date: 2015-04-01T18:14:48Z + +[Term] +id: GO:1904108 +name: protein localization to ciliary inversin compartment +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] +synonym: "protein localisation in ciliary inversin compartment" EXACT [GOC:TermGenie] +synonym: "protein localisation to ciliary inversin compartment" EXACT [GOC:TermGenie] +synonym: "protein localization in ciliary inversin compartment" EXACT [GOC:TermGenie] +is_a: GO:0061512 ! protein localization to cilium +created_by: kmv +creation_date: 2015-04-01T20:54:26Z + +[Term] +id: GO:1904109 +name: positive regulation of cholesterol import +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cholesterol import." [GO_REF:0000058, GOC:TermGenie, PMID:16772292] +synonym: "activation of cholesterol import" NARROW [GOC:TermGenie] +synonym: "activation of cholesterol uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of cholesterol uptake" EXACT [GOC:TermGenie] +synonym: "up regulation of cholesterol import" EXACT [GOC:TermGenie] +synonym: "up regulation of cholesterol uptake" EXACT [GOC:TermGenie] +synonym: "up-regulation of cholesterol import" EXACT [GOC:TermGenie] +synonym: "up-regulation of cholesterol uptake" EXACT [GOC:TermGenie] +synonym: "upregulation of cholesterol import" EXACT [GOC:TermGenie] +synonym: "upregulation of cholesterol uptake" EXACT [GOC:TermGenie] +is_a: GO:0032376 ! positive regulation of cholesterol transport +is_a: GO:0060620 ! regulation of cholesterol import +is_a: GO:2000911 ! positive regulation of sterol import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070508 ! cholesterol import +relationship: positively_regulates GO:0070508 ! cholesterol import +created_by: sl +creation_date: 2015-04-03T14:39:06Z + +[Term] +id: GO:1904110 +name: regulation of plus-end directed microfilament motor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:25717181] +synonym: "regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +is_a: GO:0120079 ! regulation of microfilament motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060002 ! plus-end directed microfilament motor activity +relationship: regulates GO:0060002 ! plus-end directed microfilament motor activity +created_by: kmv +creation_date: 2015-04-03T18:28:24Z + +[Term] +id: GO:1904111 +name: negative regulation of plus-end directed microfilament motor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:25717181] +synonym: "down regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "down regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "downregulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +synonym: "inhibition of barbed-end directed actin-filament motor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "inhibition of plus-end directed actin-filament motor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of plus-end directed microfilament motor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +is_a: GO:0120080 ! negative regulation of microfilament motor activity +is_a: GO:1904110 ! regulation of plus-end directed microfilament motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060002 ! plus-end directed microfilament motor activity +relationship: negatively_regulates GO:0060002 ! plus-end directed microfilament motor activity +created_by: kmv +creation_date: 2015-04-03T18:28:30Z + +[Term] +id: GO:1904112 +name: positive regulation of plus-end directed microfilament motor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:25717181] +synonym: "activation of barbed-end directed actin-filament motor activity" NARROW [GOC:TermGenie] +synonym: "activation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "activation of plus-end directed actin-filament motor activity" NARROW [GOC:TermGenie] +synonym: "activation of plus-end directed microfilament motor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of barbed-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of plus-end directed actin filament motor activity" RELATED [GOC:TermGenie] +synonym: "upregulation of plus-end directed actin-filament motor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of plus-end directed microfilament motor activity" EXACT [GOC:TermGenie] +is_a: GO:0120081 ! positive regulation of microfilament motor activity +is_a: GO:1904110 ! regulation of plus-end directed microfilament motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060002 ! plus-end directed microfilament motor activity +relationship: positively_regulates GO:0060002 ! plus-end directed microfilament motor activity +created_by: kmv +creation_date: 2015-04-03T18:28:35Z + +[Term] +id: GO:1904113 +name: negative regulation of muscle filament sliding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:25717181] +synonym: "down regulation of muscle filament sliding" EXACT [GOC:TermGenie] +synonym: "down-regulation of muscle filament sliding" EXACT [GOC:TermGenie] +synonym: "downregulation of muscle filament sliding" EXACT [GOC:TermGenie] +synonym: "inhibition of muscle filament sliding" NARROW [GOC:TermGenie] +is_a: GO:0032971 ! regulation of muscle filament sliding +is_a: GO:0045932 ! negative regulation of muscle contraction +is_a: GO:0051271 ! negative regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030049 ! muscle filament sliding +relationship: negatively_regulates GO:0030049 ! muscle filament sliding +created_by: kmv +creation_date: 2015-04-03T18:40:38Z + +[Term] +id: GO:1904114 +name: positive regulation of muscle filament sliding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of muscle filament sliding." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:25717181] +synonym: "activation of muscle filament sliding" NARROW [GOC:TermGenie] +synonym: "up regulation of muscle filament sliding" EXACT [GOC:TermGenie] +synonym: "up-regulation of muscle filament sliding" EXACT [GOC:TermGenie] +synonym: "upregulation of muscle filament sliding" EXACT [GOC:TermGenie] +is_a: GO:0032971 ! regulation of muscle filament sliding +is_a: GO:0045933 ! positive regulation of muscle contraction +is_a: GO:1903116 ! positive regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030049 ! muscle filament sliding +relationship: positively_regulates GO:0030049 ! muscle filament sliding +created_by: kmv +creation_date: 2015-04-03T18:40:44Z + +[Term] +id: GO:1904115 +name: axon cytoplasm +namespace: cellular_component +def: "Any cytoplasm that is part of a axon." [GO_REF:0000064, GOC:TermGenie, PMID:18667152] +synonym: "axoplasm" EXACT [] +is_a: GO:0120111 ! neuron projection cytoplasm +intersection_of: GO:0005737 ! cytoplasm +intersection_of: part_of GO:0030424 ! axon +relationship: part_of GO:0030424 ! axon +created_by: sl +creation_date: 2015-04-06T18:13:14Z + +[Term] +id: GO:1904116 +name: response to vasopressin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22811487] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-04-06T19:39:42Z + +[Term] +id: GO:1904117 +name: cellular response to vasopressin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22811487] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1904116 ! response to vasopressin +created_by: sl +creation_date: 2015-04-06T19:39:48Z + +[Term] +id: GO:1904118 +name: regulation of otic vesicle morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071600 ! otic vesicle morphogenesis +relationship: regulates GO:0071600 ! otic vesicle morphogenesis +created_by: pga +creation_date: 2015-04-07T14:00:56Z + +[Term] +id: GO:1904119 +name: negative regulation of otic vesicle morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] +synonym: "down regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of otic vesicle morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1904118 ! regulation of otic vesicle morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071600 ! otic vesicle morphogenesis +relationship: negatively_regulates GO:0071600 ! otic vesicle morphogenesis +created_by: pga +creation_date: 2015-04-07T14:01:02Z + +[Term] +id: GO:1904120 +name: positive regulation of otic vesicle morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] +synonym: "activation of otic vesicle morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1904118 ! regulation of otic vesicle morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071600 ! otic vesicle morphogenesis +relationship: positively_regulates GO:0071600 ! otic vesicle morphogenesis +created_by: pga +creation_date: 2015-04-07T14:01:08Z + +[Term] +id: GO:1904121 +name: phosphatidylethanolamine transfer activity +namespace: molecular_function +def: "Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle." [GO_REF:0000066, GOC:TermGenie, PMID:8606365] +synonym: "intermembrane phosphatidylethanolamine transfer activity" NARROW [] +synonym: "phosphatidylethanolamine carrier activity" EXACT [] +synonym: "phosphatidylethanolamine transporter activity" BROAD [] +is_a: GO:0120014 ! phospholipid transfer activity +created_by: sl +creation_date: 2015-04-07T22:51:34Z + +[Term] +id: GO:1904122 +name: positive regulation of fatty acid beta-oxidation by octopamine signaling pathway +namespace: biological_process +def: "An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation." [GO_REF:0000063, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24120942] +synonym: "activation of fatty acid beta-oxidation by octopamine signaling pathway" NARROW [GOC:TermGenie] +synonym: "stimulation of fatty acid beta-oxidation by octopamine signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of fatty acid beta-oxidation by octopamine signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of fatty acid beta-oxidation by octopamine signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of fatty acid beta-oxidation by octopamine signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0032000 ! positive regulation of fatty acid beta-oxidation +is_a: GO:0071927 ! octopamine signaling pathway +intersection_of: GO:0071927 ! octopamine signaling pathway +intersection_of: positively_regulates GO:0006635 ! fatty acid beta-oxidation +created_by: kmv +creation_date: 2015-04-08T21:03:13Z + +[Term] +id: GO:1904123 +name: positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway +namespace: biological_process +def: "A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation." [GO_REF:0000063, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24120942] +synonym: "activation of fatty acid beta-oxidation by serotonin receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "stimulation of fatty acid beta-oxidation by serotonin receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "up regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of fatty acid beta-oxidation by serotonin receptor signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0007210 ! serotonin receptor signaling pathway +is_a: GO:0032000 ! positive regulation of fatty acid beta-oxidation +intersection_of: GO:0007210 ! serotonin receptor signaling pathway +intersection_of: positively_regulates GO:0006635 ! fatty acid beta-oxidation +created_by: kmv +creation_date: 2015-04-08T21:03:20Z + +[Term] +id: GO:1904124 +name: microglial cell migration +namespace: biological_process +def: "The orderly movement of a microglial cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +is_a: GO:0008347 ! glial cell migration +is_a: GO:1905517 ! macrophage migration +created_by: nc +creation_date: 2015-04-10T16:04:49Z + +[Term] +id: GO:1904125 +name: convergent extension involved in rhombomere morphogenesis +namespace: biological_process +def: "Any convergent extension that is involved in rhombomere morphogenesis." [GO_REF:0000060, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:0060027 ! convergent extension involved in gastrulation +is_a: GO:0060029 ! convergent extension involved in organogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0021593 ! rhombomere morphogenesis +relationship: part_of GO:0021593 ! rhombomere morphogenesis +created_by: dph +creation_date: 2015-04-10T21:12:50Z + +[Term] +id: GO:1904126 +name: convergent extension involved in notochord morphogenesis +namespace: biological_process +def: "Any convergent extension that is involved in notochord morphogenesis." [GO_REF:0000060, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:0060027 ! convergent extension involved in gastrulation +is_a: GO:0060029 ! convergent extension involved in organogenesis +intersection_of: GO:0060026 ! convergent extension +intersection_of: part_of GO:0048570 ! notochord morphogenesis +relationship: part_of GO:0048570 ! notochord morphogenesis +created_by: dph +creation_date: 2015-04-10T21:12:57Z + +[Term] +id: GO:1904127 +name: regulation of convergent extension involved in somitogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:0014807 ! regulation of somitogenesis +is_a: GO:1901232 ! regulation of convergent extension involved in axis elongation +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090246 ! convergent extension involved in somitogenesis +relationship: regulates GO:0090246 ! convergent extension involved in somitogenesis +created_by: dph +creation_date: 2015-04-10T21:13:04Z + +[Term] +id: GO:1904128 +name: negative regulation of convergent extension involved in somitogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in somitogenesis" NARROW [GOC:TermGenie] +is_a: GO:1901233 ! negative regulation of convergent extension involved in axis elongation +is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation +is_a: GO:1904127 ! regulation of convergent extension involved in somitogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090246 ! convergent extension involved in somitogenesis +relationship: negatively_regulates GO:0090246 ! convergent extension involved in somitogenesis +created_by: dph +creation_date: 2015-04-10T21:13:10Z + +[Term] +id: GO:1904129 +name: positive regulation of convergent extension involved in somitogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "activation of convergent extension involved in somitogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in somitogenesis" EXACT [GOC:TermGenie] +is_a: GO:1901234 ! positive regulation of convergent extension involved in axis elongation +is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation +is_a: GO:1904127 ! regulation of convergent extension involved in somitogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090246 ! convergent extension involved in somitogenesis +relationship: positively_regulates GO:0090246 ! convergent extension involved in somitogenesis +created_by: dph +creation_date: 2015-04-10T21:13:15Z + +[Term] +id: GO:1904130 +name: regulation of convergent extension involved in neural plate elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022007 ! convergent extension involved in neural plate elongation +relationship: regulates GO:0022007 ! convergent extension involved in neural plate elongation +created_by: dph +creation_date: 2015-04-10T21:13:21Z + +[Term] +id: GO:1904131 +name: negative regulation of convergent extension involved in neural plate elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in neural plate elongation" NARROW [GOC:TermGenie] +is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation +is_a: GO:1904130 ! regulation of convergent extension involved in neural plate elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022007 ! convergent extension involved in neural plate elongation +relationship: negatively_regulates GO:0022007 ! convergent extension involved in neural plate elongation +created_by: dph +creation_date: 2015-04-10T21:13:27Z + +[Term] +id: GO:1904132 +name: positive regulation of convergent extension involved in neural plate elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "activation of convergent extension involved in neural plate elongation" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in neural plate elongation" EXACT [GOC:TermGenie] +is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation +is_a: GO:1904130 ! regulation of convergent extension involved in neural plate elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022007 ! convergent extension involved in neural plate elongation +relationship: positively_regulates GO:0022007 ! convergent extension involved in neural plate elongation +created_by: dph +creation_date: 2015-04-10T21:13:33Z + +[Term] +id: GO:1904133 +name: regulation of convergent extension involved in rhombomere morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +relationship: regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:12Z + +[Term] +id: GO:1904134 +name: negative regulation of convergent extension involved in rhombomere morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in rhombomere morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation +is_a: GO:1904133 ! regulation of convergent extension involved in rhombomere morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +relationship: negatively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:18Z + +[Term] +id: GO:1904135 +name: positive regulation of convergent extension involved in rhombomere morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "activation of convergent extension involved in rhombomere morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in rhombomere morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation +is_a: GO:1904133 ! regulation of convergent extension involved in rhombomere morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +relationship: positively_regulates GO:1904125 ! convergent extension involved in rhombomere morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:24Z + +[Term] +id: GO:1904136 +name: regulation of convergent extension involved in notochord morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +is_a: GO:1904103 ! regulation of convergent extension involved in gastrulation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +relationship: regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:30Z + +[Term] +id: GO:1904137 +name: negative regulation of convergent extension involved in notochord morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "down regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of convergent extension involved in notochord morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1904104 ! negative regulation of convergent extension involved in gastrulation +is_a: GO:1904136 ! regulation of convergent extension involved in notochord morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +relationship: negatively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:36Z + +[Term] +id: GO:1904138 +name: positive regulation of convergent extension involved in notochord morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:24892953] +synonym: "activation of convergent extension involved in notochord morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of convergent extension involved in notochord morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1904105 ! positive regulation of convergent extension involved in gastrulation +is_a: GO:1904136 ! regulation of convergent extension involved in notochord morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +relationship: positively_regulates GO:1904126 ! convergent extension involved in notochord morphogenesis +created_by: dph +creation_date: 2015-04-10T21:21:41Z + +[Term] +id: GO:1904139 +name: regulation of microglial cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microglial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +is_a: GO:1903975 ! regulation of glial cell migration +is_a: GO:1905521 ! regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904124 ! microglial cell migration +relationship: regulates GO:1904124 ! microglial cell migration +created_by: nc +creation_date: 2015-04-13T09:06:57Z + +[Term] +id: GO:1904140 +name: negative regulation of microglial cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of microglial cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of microglial cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of microglial cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of microglial cell migration" NARROW [GOC:TermGenie] +is_a: GO:1903976 ! negative regulation of glial cell migration +is_a: GO:1904139 ! regulation of microglial cell migration +is_a: GO:1905522 ! negative regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904124 ! microglial cell migration +relationship: negatively_regulates GO:1904124 ! microglial cell migration +created_by: nc +creation_date: 2015-04-13T09:07:03Z + +[Term] +id: GO:1904141 +name: positive regulation of microglial cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microglial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of microglial cell migration" NARROW [GOC:TermGenie] +synonym: "up regulation of microglial cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of microglial cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of microglial cell migration" EXACT [GOC:TermGenie] +is_a: GO:1903977 ! positive regulation of glial cell migration +is_a: GO:1904139 ! regulation of microglial cell migration +is_a: GO:1905523 ! positive regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904124 ! microglial cell migration +relationship: positively_regulates GO:1904124 ! microglial cell migration +created_by: nc +creation_date: 2015-04-13T09:07:11Z + +[Term] +id: GO:1904142 +name: negative regulation of carotenoid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:25675505] +synonym: "down regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of carotenoid anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of carotenoid biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of carotenoid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of carotenoid formation" NARROW [GOC:TermGenie] +synonym: "inhibition of carotenoid synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051055 ! negative regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016117 ! carotenoid biosynthetic process +relationship: negatively_regulates GO:0016117 ! carotenoid biosynthetic process +created_by: tb +creation_date: 2015-04-13T19:39:13Z + +[Term] +id: GO:1904143 +name: positive regulation of carotenoid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:25675505] +synonym: "activation of carotenoid anabolism" NARROW [GOC:TermGenie] +synonym: "activation of carotenoid biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of carotenoid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of carotenoid formation" NARROW [GOC:TermGenie] +synonym: "activation of carotenoid synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of carotenoid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of carotenoid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of carotenoid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of carotenoid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of carotenoid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of carotenoid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016117 ! carotenoid biosynthetic process +relationship: positively_regulates GO:0016117 ! carotenoid biosynthetic process +created_by: tb +creation_date: 2015-04-13T19:39:19Z + +[Term] +id: GO:1904144 +name: phosphatidylinositol phosphate phosphatase complex +namespace: cellular_component +def: "A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:12525165] +comment: An example of this is ACPP in human (P15309) in PMID:12525165 (inferred from physical interaction). +synonym: "prostatic acid phosphatase complex" NARROW [] +is_a: GO:1903293 ! phosphatase complex +created_by: bhm +creation_date: 2015-04-14T11:22:53Z + +[Term] +id: GO:1904145 +name: negative regulation of meiotic cell cycle process involved in oocyte maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] +synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:1900194 ! negative regulation of oocyte maturation +is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +relationship: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +created_by: tb +creation_date: 2015-04-14T15:59:22Z + +[Term] +id: GO:1904146 +name: positive regulation of meiotic cell cycle process involved in oocyte maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] +synonym: "activation of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1900195 ! positive regulation of oocyte maturation +is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +relationship: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation +created_by: tb +creation_date: 2015-04-14T15:59:28Z + +[Term] +id: GO:1904147 +name: response to nonylphenol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:19260726] +is_a: GO:0010033 ! response to organic substance +created_by: sl +creation_date: 2015-04-14T17:01:44Z + +[Term] +id: GO:1904148 +name: cellular response to nonylphenol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:19260726] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1904147 ! response to nonylphenol +created_by: sl +creation_date: 2015-04-14T17:01:50Z + +[Term] +id: GO:1904149 +name: regulation of microglial cell mediated cytotoxicity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +is_a: GO:0001910 ! regulation of leukocyte mediated cytotoxicity +is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090634 ! microglial cell mediated cytotoxicity +relationship: regulates GO:0090634 ! microglial cell mediated cytotoxicity +created_by: nc +creation_date: 2015-04-15T08:05:29Z + +[Term] +id: GO:1904150 +name: negative regulation of microglial cell mediated cytotoxicity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "down regulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +synonym: "down-regulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +synonym: "downregulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +synonym: "inhibition of microglial cell mediated cytotoxicity" NARROW [GOC:TermGenie] +is_a: GO:0001911 ! negative regulation of leukocyte mediated cytotoxicity +is_a: GO:0002887 ! negative regulation of myeloid leukocyte mediated immunity +is_a: GO:1904149 ! regulation of microglial cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090634 ! microglial cell mediated cytotoxicity +relationship: negatively_regulates GO:0090634 ! microglial cell mediated cytotoxicity +created_by: nc +creation_date: 2015-04-15T08:05:35Z + +[Term] +id: GO:1904151 +name: positive regulation of microglial cell mediated cytotoxicity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] +synonym: "activation of microglial cell mediated cytotoxicity" NARROW [GOC:TermGenie] +synonym: "up regulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +synonym: "up-regulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +synonym: "upregulation of microglial cell mediated cytotoxicity" EXACT [GOC:TermGenie] +is_a: GO:0001912 ! positive regulation of leukocyte mediated cytotoxicity +is_a: GO:0002888 ! positive regulation of myeloid leukocyte mediated immunity +is_a: GO:1904149 ! regulation of microglial cell mediated cytotoxicity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090634 ! microglial cell mediated cytotoxicity +relationship: positively_regulates GO:0090634 ! microglial cell mediated cytotoxicity +created_by: nc +creation_date: 2015-04-15T08:05:42Z + +[Term] +id: GO:1904152 +name: regulation of retrograde protein transport, ER to cytosol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18555783] +synonym: "regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "regulation of protein retrotranslocation from ER" EXACT [GOC:bf] +synonym: "regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +is_a: GO:0070861 ! regulation of protein exit from endoplasmic reticulum +is_a: GO:1904292 ! regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030970 ! retrograde protein transport, ER to cytosol +relationship: regulates GO:0030970 ! retrograde protein transport, ER to cytosol +created_by: bf +creation_date: 2015-04-15T09:23:06Z + +[Term] +id: GO:1904153 +name: negative regulation of retrograde protein transport, ER to cytosol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18555783] +synonym: "down regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "down regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "down regulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "downregulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "inhibition of protein dislocation from ER" NARROW [GOC:TermGenie] +synonym: "inhibition of retrograde protein transport, endoplasmic reticulum to cytosol" NARROW [GOC:TermGenie] +synonym: "inhibition of retrograde protein transport, ER to cytosol" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein retrotranslocation from ER" EXACT [GOC:bf] +synonym: "negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +is_a: GO:0070862 ! negative regulation of protein exit from endoplasmic reticulum +is_a: GO:1904152 ! regulation of retrograde protein transport, ER to cytosol +is_a: GO:1904293 ! negative regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030970 ! retrograde protein transport, ER to cytosol +relationship: negatively_regulates GO:0030970 ! retrograde protein transport, ER to cytosol +created_by: bf +creation_date: 2015-04-15T09:23:13Z + +[Term] +id: GO:1904154 +name: positive regulation of retrograde protein transport, ER to cytosol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18555783] +synonym: "activation of protein dislocation from ER" NARROW [GOC:TermGenie] +synonym: "activation of retrograde protein transport, endoplasmic reticulum to cytosol" NARROW [GOC:TermGenie] +synonym: "activation of retrograde protein transport, ER to cytosol" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein retrotranslocation from ER" EXACT [GOC:bf] +synonym: "positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "up regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "up regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "up regulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein retrotranslocation from ER" EXACT [GOC:bf] +synonym: "up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "up-regulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "upregulation of protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde protein transport, ER to cytosol" EXACT [GOC:TermGenie] +is_a: GO:0070863 ! positive regulation of protein exit from endoplasmic reticulum +is_a: GO:1904152 ! regulation of retrograde protein transport, ER to cytosol +is_a: GO:1904294 ! positive regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030970 ! retrograde protein transport, ER to cytosol +relationship: positively_regulates GO:0030970 ! retrograde protein transport, ER to cytosol +created_by: bf +creation_date: 2015-04-15T09:23:19Z + +[Term] +id: GO:1904155 +name: DN2 thymocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-." [GO_REF:0000086, GOC:dph, GOC:TermGenie, PMID:25398325] +is_a: GO:0033077 ! T cell differentiation in thymus +created_by: dph +creation_date: 2015-04-15T12:52:53Z + +[Term] +id: GO:1904156 +name: DN3 thymocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+." [GO_REF:0000086, GOC:dph, GOC:TermGenie, PMID:25398325] +is_a: GO:0033077 ! T cell differentiation in thymus +created_by: dph +creation_date: 2015-04-15T12:53:00Z + +[Term] +id: GO:1904157 +name: DN4 thymocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-." [GO_REF:0000086, GOC:dph, GOC:TermGenie, PMID:25398325] +is_a: GO:0033077 ! T cell differentiation in thymus +created_by: dph +creation_date: 2015-04-15T12:53:07Z + +[Term] +id: GO:1904158 +name: axonemal central apparatus assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:9295136] +synonym: "axonemal central apparatus formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0035082 ! axoneme assembly +created_by: krc +creation_date: 2015-04-16T18:46:11Z + +[Term] +id: GO:1904159 +name: megasporocyte differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte." [GO_REF:0000086, GOC:tair_curators, GOC:TermGenie] +comment: The process aimed at the progression of a megasporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A megasporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) megaspores; also called megaspore mother cell. +synonym: "megaspore mother cell differentiation" EXACT [GOC:tair_curators] +is_a: GO:0048533 ! sporocyte differentiation +created_by: lr +creation_date: 2015-04-17T20:25:14Z + +[Term] +id: GO:1904160 +name: protein localization to chloroplast starch grain +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain." [GO_REF:0000087, GOC:TermGenie, PMID:25710501] +synonym: "protein localisation in chloroplast starch grain" EXACT [GOC:TermGenie] +synonym: "protein localisation to chloroplast starch grain" EXACT [GOC:TermGenie] +synonym: "protein localization in chloroplast starch grain" EXACT [GOC:TermGenie] +is_a: GO:0072598 ! protein localization to chloroplast +created_by: lr +creation_date: 2015-04-20T18:06:17Z + +[Term] +id: GO:1904161 +name: DNA synthesis involved in UV-damage excision repair +namespace: biological_process +def: "Any DNA synthesis that is involved in UV-damage excision repair." [GO_REF:0000060, GOC:TermGenie, PMID:10704216] +synonym: "DNA synthesis during UV-damage excision repair" RELATED [GOC:TermGenie] +synonym: "DNA synthesis during UV-damaged DNA endonuclease-dependent excision repair" RELATED [GOC:TermGenie] +synonym: "DNA synthesis during UVDE-dependent excision repair" RELATED [GOC:TermGenie] +synonym: "DNA synthesis during UVER" RELATED [GOC:TermGenie] +synonym: "DNA synthesis involved in AER" RELATED [GOC:mah, PMID:10704216] +synonym: "DNA synthesis involved in alternative excision repair" RELATED [GOC:mah, PMID:10704216] +synonym: "DNA synthesis involved in UV-damaged DNA endonuclease-dependent excision repair" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in UVDE-dependent excision repair" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in UVER" EXACT [GOC:TermGenie] +synonym: "mitotic DNA repair synthesis involved in UV-damage excision repair" NARROW [GOC:TermGenie] +synonym: "mitotic DNA repair synthesis involved in UV-damaged DNA endonuclease-dependent excision repair" NARROW [GOC:TermGenie] +synonym: "mitotic DNA repair synthesis involved in UVDE-dependent excision repair" NARROW [GOC:TermGenie] +synonym: "mitotic DNA repair synthesis involved in UVER" NARROW [GOC:TermGenie] +is_a: GO:0000731 ! DNA synthesis involved in DNA repair +intersection_of: GO:0000731 ! DNA synthesis involved in DNA repair +intersection_of: part_of GO:0070914 ! UV-damage excision repair +relationship: part_of GO:0070914 ! UV-damage excision repair +created_by: mah +creation_date: 2015-04-21T14:53:12Z + +[Term] +id: GO:1904162 +name: 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair +namespace: molecular_function +def: "Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair." [GO_REF:0000061, GOC:TermGenie, PMID:10704216] +synonym: "5'-3' exodeoxyribonuclease activity involved in AER" RELATED [GOC:mah] +synonym: "5'-3' exodeoxyribonuclease activity involved in alternative excision repair" RELATED [GOC:mah] +synonym: "5'-3' exodeoxyribonuclease activity involved in UV-damaged DNA endonuclease-dependent excision repair" EXACT [GOC:TermGenie] +synonym: "5'-3' exodeoxyribonuclease activity involved in UVDE-dependent excision repair" EXACT [GOC:TermGenie] +synonym: "5'-3' exodeoxyribonuclease activity involved in UVER" EXACT [GOC:TermGenie] +is_a: GO:0035312 ! 5'-3' exodeoxyribonuclease activity +intersection_of: GO:0035312 ! 5'-3' exodeoxyribonuclease activity +intersection_of: part_of GO:0070914 ! UV-damage excision repair +relationship: part_of GO:0070914 ! UV-damage excision repair +created_by: mah +creation_date: 2015-04-21T14:53:19Z + +[Term] +id: GO:1904163 +name: obsolete regulation of triglyceride homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:22541436] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rph +creation_date: 2015-04-22T11:04:43Z + +[Term] +id: GO:1904164 +name: obsolete negative regulation of triglyceride homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride homeostasis." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:22541436] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "down regulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +synonym: "down-regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "down-regulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +synonym: "downregulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "downregulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +synonym: "inhibition of triacylglycerol homeostasis" NARROW [GOC:TermGenie] +synonym: "inhibition of triglyceride homeostasis" NARROW [GOC:TermGenie] +synonym: "negative regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rph +creation_date: 2015-04-22T11:04:49Z + +[Term] +id: GO:1904165 +name: obsolete positive regulation of triglyceride homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of triglyceride homeostasis." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:22541436] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of triacylglycerol homeostasis" NARROW [GOC:TermGenie] +synonym: "activation of triglyceride homeostasis" NARROW [GOC:TermGenie] +synonym: "positive regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "up regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "up regulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +synonym: "up-regulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "up-regulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +synonym: "upregulation of triacylglycerol homeostasis" EXACT [GOC:TermGenie] +synonym: "upregulation of triglyceride homeostasis" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: rph +creation_date: 2015-04-22T11:04:55Z + +[Term] +id: GO:1904166 +name: obsolete negative regulation of cholesterol homeostasis +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol homeostasis." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:22541436] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of cholesterol homeostasis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cholesterol homeostasis" EXACT [GOC:TermGenie] +synonym: "downregulation of cholesterol homeostasis" EXACT [GOC:TermGenie] +synonym: "inhibition of cholesterol homeostasis" NARROW [GOC:TermGenie] +is_obsolete: true +created_by: rph +creation_date: 2015-04-22T11:11:12Z + +[Term] +id: GO:1904170 +name: regulation of bleb assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] +synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032060 ! bleb assembly +relationship: regulates GO:0032060 ! bleb assembly +created_by: als +creation_date: 2015-04-23T09:32:19Z + +[Term] +id: GO:1904171 +name: negative regulation of bleb assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] +synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "inhibition of bleb assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of cell blebbing" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie] +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:1904170 ! regulation of bleb assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032060 ! bleb assembly +relationship: negatively_regulates GO:0032060 ! bleb assembly +created_by: als +creation_date: 2015-04-23T09:32:25Z + +[Term] +id: GO:1904172 +name: positive regulation of bleb assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] +synonym: "activation of bleb assembly" NARROW [GOC:TermGenie] +synonym: "activation of cell blebbing" NARROW [GOC:TermGenie] +synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie] +synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie] +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:1904170 ! regulation of bleb assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032060 ! bleb assembly +relationship: positively_regulates GO:0032060 ! bleb assembly +created_by: als +creation_date: 2015-04-23T09:32:31Z + +[Term] +id: GO:1904173 +name: regulation of histone demethylase activity (H3-K4 specific) +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific)." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:24843136] +is_a: GO:0031056 ! regulation of histone modification +is_a: GO:0050790 ! regulation of catalytic activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +relationship: regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +created_by: dph +creation_date: 2015-04-24T19:29:32Z + +[Term] +id: GO:1904174 +name: negative regulation of histone demethylase activity (H3-K4 specific) +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific)." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:24843136] +synonym: "down regulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +synonym: "downregulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +synonym: "inhibition of histone demethylase activity (H3-K4 specific)" NARROW [GOC:TermGenie] +is_a: GO:0031057 ! negative regulation of histone modification +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:1904173 ! regulation of histone demethylase activity (H3-K4 specific) +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +relationship: negatively_regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +created_by: dph +creation_date: 2015-04-24T19:29:38Z + +[Term] +id: GO:1904175 +name: positive regulation of histone demethylase activity (H3-K4 specific) +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific)." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:24843136] +synonym: "activation of histone demethylase activity (H3-K4 specific)" NARROW [GOC:TermGenie] +synonym: "up regulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +synonym: "upregulation of histone demethylase activity (H3-K4 specific)" EXACT [GOC:TermGenie] +is_a: GO:0031058 ! positive regulation of histone modification +is_a: GO:0043085 ! positive regulation of catalytic activity +is_a: GO:1904173 ! regulation of histone demethylase activity (H3-K4 specific) +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +relationship: positively_regulates GO:0032453 ! histone demethylase activity (H3-K4 specific) +created_by: dph +creation_date: 2015-04-24T19:29:45Z + +[Term] +id: GO:1904176 +name: carbon phosphorus lyase complex +namespace: cellular_component +def: "A protein complex which is capable of carbon phosphorus lyase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:17993513, PMID:21705661, PMID:22089136, PMID:23830682] +comment: An example of this is PhnJ in E. coli (P16688) in PMID:22089136 (inferred from direct assay). +xref: IntAct:EBI-6471348 +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2015-04-29T08:17:13Z + +[Term] +id: GO:1904177 +name: regulation of adipose tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] +synonym: "regulation of adipogenesis" RELATED [GOC:TermGenie] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060612 ! adipose tissue development +relationship: regulates GO:0060612 ! adipose tissue development +created_by: sl +creation_date: 2015-04-29T20:01:01Z + +[Term] +id: GO:1904178 +name: negative regulation of adipose tissue development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] +synonym: "down regulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie] +synonym: "down-regulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie] +synonym: "downregulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie] +synonym: "inhibition of adipogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of adipose tissue development" NARROW [GOC:TermGenie] +synonym: "negative regulation of adipogenesis" RELATED [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904177 ! regulation of adipose tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060612 ! adipose tissue development +relationship: negatively_regulates GO:0060612 ! adipose tissue development +created_by: sl +creation_date: 2015-04-29T20:01:07Z + +[Term] +id: GO:1904179 +name: positive regulation of adipose tissue development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] +synonym: "activation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "activation of adipose tissue development" NARROW [GOC:TermGenie] +synonym: "positive regulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie] +synonym: "up-regulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie] +synonym: "upregulation of adipogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904177 ! regulation of adipose tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060612 ! adipose tissue development +relationship: positively_regulates GO:0060612 ! adipose tissue development +created_by: sl +creation_date: 2015-04-29T20:01:13Z + +[Term] +id: GO:1904180 +name: negative regulation of membrane depolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization." [GO_REF:0000058, GOC:TermGenie, PMID:20826763] +synonym: "down regulation of membrane depolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane depolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane depolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane depolarization" NARROW [GOC:TermGenie] +is_a: GO:0003254 ! regulation of membrane depolarization +is_a: GO:0048519 ! negative regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051899 ! membrane depolarization +relationship: negatively_regulates GO:0051899 ! membrane depolarization +created_by: sl +creation_date: 2015-04-29T22:29:25Z + +[Term] +id: GO:1904181 +name: positive regulation of membrane depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane depolarization." [GO_REF:0000058, GOC:TermGenie, PMID:20826763] +synonym: "activation of membrane depolarization" NARROW [GOC:TermGenie] +synonym: "up regulation of membrane depolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane depolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane depolarization" EXACT [GOC:TermGenie] +is_a: GO:0003254 ! regulation of membrane depolarization +is_a: GO:0048518 ! positive regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051899 ! membrane depolarization +relationship: positively_regulates GO:0051899 ! membrane depolarization +created_by: sl +creation_date: 2015-04-29T22:29:31Z + +[Term] +id: GO:1904182 +name: regulation of pyruvate dehydrogenase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:25525879] +synonym: "regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004738 ! pyruvate dehydrogenase activity +relationship: regulates GO:0004738 ! pyruvate dehydrogenase activity +created_by: dph +creation_date: 2015-05-05T14:17:27Z + +[Term] +id: GO:1904183 +name: negative regulation of pyruvate dehydrogenase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:25525879] +synonym: "down regulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of pyruvate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of pyruvic acid dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of pyruvic dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1904182 ! regulation of pyruvate dehydrogenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004738 ! pyruvate dehydrogenase activity +relationship: negatively_regulates GO:0004738 ! pyruvate dehydrogenase activity +created_by: dph +creation_date: 2015-05-05T14:17:33Z + +[Term] +id: GO:1904184 +name: positive regulation of pyruvate dehydrogenase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:25525879] +synonym: "activation of pyruvate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of pyruvic acid dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of pyruvic dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pyruvate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1904182 ! regulation of pyruvate dehydrogenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004738 ! pyruvate dehydrogenase activity +relationship: positively_regulates GO:0004738 ! pyruvate dehydrogenase activity +created_by: dph +creation_date: 2015-05-05T14:17:39Z + +[Term] +id: GO:1904185 +name: equatorial microtubule organizing center assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center." [GO_REF:0000079, GOC:TermGenie, PMID:15004232] +synonym: "EMTOC assembly" EXACT [GOC:TermGenie] +synonym: "EMTOC formation" EXACT [GOC:TermGenie] +synonym: "equatorial microtubule organising centre assembly" EXACT [GOC:TermGenie] +synonym: "equatorial microtubule organising centre formation" EXACT [GOC:TermGenie] +synonym: "equatorial microtubule organizing center formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0031023 ! microtubule organizing center organization +created_by: mah +creation_date: 2015-05-05T14:24:30Z + +[Term] +id: GO:1904186 +name: post-anaphase microtubule array organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array." [GOC:TermGenie, PMID:15004232] +synonym: "PAA organization" EXACT [GOC:TermGenie] +synonym: "post-anaphase array organization" EXACT [GOC:TermGenie] +synonym: "post-anaphase microtubule array organisation" EXACT [] +is_a: GO:0016043 ! cellular component organization +created_by: mah +creation_date: 2015-05-05T14:40:16Z + +[Term] +id: GO:1904187 +name: regulation of transformation of host cell by virus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transformation of host cell by virus." [GO_REF:0000058, GOC:TermGenie, PMID:12200142] +synonym: "regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019087 ! transformation of host cell by virus +relationship: regulates GO:0019087 ! transformation of host cell by virus +created_by: pga +creation_date: 2015-05-05T15:29:58Z + +[Term] +id: GO:1904188 +name: negative regulation of transformation of host cell by virus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus." [GO_REF:0000058, GOC:TermGenie, PMID:12200142] +synonym: "down regulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "down regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "down regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "downregulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "downregulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "downregulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "inhibition of transformation of host cell by virus" NARROW [GOC:TermGenie] +synonym: "inhibition of viral transformation" NARROW [GOC:TermGenie] +synonym: "inhibition of viral transformation of host cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +is_a: GO:0048525 ! negative regulation of viral process +is_a: GO:1904187 ! regulation of transformation of host cell by virus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019087 ! transformation of host cell by virus +relationship: negatively_regulates GO:0019087 ! transformation of host cell by virus +created_by: pga +creation_date: 2015-05-05T15:30:04Z + +[Term] +id: GO:1904189 +name: positive regulation of transformation of host cell by virus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus." [GO_REF:0000058, GOC:TermGenie, PMID:12200142] +synonym: "activation of transformation of host cell by virus" NARROW [GOC:TermGenie] +synonym: "activation of viral transformation" NARROW [GOC:TermGenie] +synonym: "activation of viral transformation of host cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "up regulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "up regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "up regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral transformation of host cell" EXACT [GOC:TermGenie] +synonym: "upregulation of transformation of host cell by virus" EXACT [GOC:TermGenie] +synonym: "upregulation of viral transformation" EXACT [GOC:TermGenie] +synonym: "upregulation of viral transformation of host cell" EXACT [GOC:TermGenie] +is_a: GO:0048524 ! positive regulation of viral process +is_a: GO:1904187 ! regulation of transformation of host cell by virus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019087 ! transformation of host cell by virus +relationship: positively_regulates GO:0019087 ! transformation of host cell by virus +created_by: pga +creation_date: 2015-05-05T15:30:11Z + +[Term] +id: GO:1904191 +name: positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division +namespace: biological_process +def: "Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division." [GO_REF:0000060, GOC:TermGenie, PMID:15791259] +synonym: "activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division" NARROW [GOC:TermGenie] +synonym: "positive regulation of CDK activity involved in meiotic nuclear division" EXACT [GOC:TermGenie] +synonym: "positive regulation of cyclin-dependent protein kinase activity involved in meiosis" BROAD [GOC:TermGenie] +synonym: "stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division" NARROW [GOC:TermGenie] +synonym: "up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division" EXACT [GOC:TermGenie] +is_a: GO:0040020 ! regulation of meiotic nuclear division +is_a: GO:0045737 ! positive regulation of cyclin-dependent protein serine/threonine kinase activity +intersection_of: GO:0045737 ! positive regulation of cyclin-dependent protein serine/threonine kinase activity +intersection_of: regulates GO:0140013 ! meiotic nuclear division +created_by: al +creation_date: 2015-05-06T14:48:52Z + +[Term] +id: GO:1904192 +name: regulation of cholangiocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] +synonym: "regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902488 ! cholangiocyte apoptotic process +relationship: regulates GO:1902488 ! cholangiocyte apoptotic process +created_by: sl +creation_date: 2015-05-06T15:25:48Z + +[Term] +id: GO:1904193 +name: negative regulation of cholangiocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] +synonym: "down regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process +relationship: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process +created_by: sl +creation_date: 2015-05-06T15:25:55Z + +[Term] +id: GO:1904194 +name: positive regulation of cholangiocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] +synonym: "activation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902488 ! cholangiocyte apoptotic process +relationship: positively_regulates GO:1902488 ! cholangiocyte apoptotic process +created_by: sl +creation_date: 2015-05-06T15:26:00Z + +[Term] +id: GO:1904195 +name: regulation of granulosa cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of granulosa cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:22383759] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990739 ! granulosa cell proliferation +relationship: regulates GO:1990739 ! granulosa cell proliferation +created_by: sl +creation_date: 2015-05-07T17:02:25Z + +[Term] +id: GO:1904196 +name: negative regulation of granulosa cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:22383759] +synonym: "down regulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of granulosa cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:1904195 ! regulation of granulosa cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990739 ! granulosa cell proliferation +relationship: negatively_regulates GO:1990739 ! granulosa cell proliferation +created_by: sl +creation_date: 2015-05-07T17:02:34Z + +[Term] +id: GO:1904197 +name: positive regulation of granulosa cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:22383759] +synonym: "activation of granulosa cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of granulosa cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:1904195 ! regulation of granulosa cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990739 ! granulosa cell proliferation +relationship: positively_regulates GO:1990739 ! granulosa cell proliferation +created_by: sl +creation_date: 2015-05-07T17:02:40Z + +[Term] +id: GO:1904198 +name: negative regulation of regulation of vascular smooth muscle cell membrane depolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization." [GO_REF:0000058, GOC:TermGenie, PMID:20826763] +synonym: "down regulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of regulation of vascular smooth muscle cell membrane depolarization" NARROW [GOC:TermGenie] +is_a: GO:1904180 ! negative regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990736 ! regulation of vascular smooth muscle cell membrane depolarization +relationship: negatively_regulates GO:1990736 ! regulation of vascular smooth muscle cell membrane depolarization +created_by: sl +creation_date: 2015-05-07T17:16:44Z + +[Term] +id: GO:1904199 +name: positive regulation of regulation of vascular smooth muscle cell membrane depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization." [GO_REF:0000058, GOC:TermGenie, PMID:20826763] +synonym: "activation of regulation of vascular smooth muscle cell membrane depolarization" NARROW [GOC:TermGenie] +synonym: "up regulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of vascular smooth muscle cell membrane depolarization" EXACT [GOC:TermGenie] +is_a: GO:1904181 ! positive regulation of membrane depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990736 ! regulation of vascular smooth muscle cell membrane depolarization +relationship: positively_regulates GO:1990736 ! regulation of vascular smooth muscle cell membrane depolarization +created_by: sl +creation_date: 2015-05-07T17:16:50Z + +[Term] +id: GO:1904200 +name: iodide transmembrane transport +namespace: biological_process +def: "The process in which iodide is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:20392814] +is_a: GO:0015705 ! iodide transport +is_a: GO:0098661 ! inorganic anion transmembrane transport +created_by: sl +creation_date: 2015-05-08T15:17:19Z + +[Term] +id: GO:1904201 +name: regulation of iodide transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of iodide transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015705 ! iodide transport +relationship: regulates GO:0015705 ! iodide transport +created_by: sl +creation_date: 2015-05-08T15:19:57Z + +[Term] +id: GO:1904202 +name: negative regulation of iodide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +synonym: "down regulation of iodide transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of iodide transport" EXACT [GOC:TermGenie] +synonym: "downregulation of iodide transport" EXACT [GOC:TermGenie] +synonym: "inhibition of iodide transport" NARROW [GOC:TermGenie] +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:1904201 ! regulation of iodide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015705 ! iodide transport +relationship: negatively_regulates GO:0015705 ! iodide transport +created_by: sl +creation_date: 2015-05-08T15:20:03Z + +[Term] +id: GO:1904203 +name: positive regulation of iodide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of iodide transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +synonym: "activation of iodide transport" NARROW [GOC:TermGenie] +synonym: "up regulation of iodide transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of iodide transport" EXACT [GOC:TermGenie] +synonym: "upregulation of iodide transport" EXACT [GOC:TermGenie] +is_a: GO:1903793 ! positive regulation of anion transport +is_a: GO:1904201 ! regulation of iodide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015705 ! iodide transport +relationship: positively_regulates GO:0015705 ! iodide transport +created_by: sl +creation_date: 2015-05-08T15:20:09Z + +[Term] +id: GO:1904204 +name: regulation of skeletal muscle hypertrophy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] +is_a: GO:0014733 ! regulation of skeletal muscle adaptation +is_a: GO:0014743 ! regulation of muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014734 ! skeletal muscle hypertrophy +relationship: regulates GO:0014734 ! skeletal muscle hypertrophy +created_by: sl +creation_date: 2015-05-08T17:38:13Z + +[Term] +id: GO:1904205 +name: negative regulation of skeletal muscle hypertrophy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] +synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "inhibition of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] +is_a: GO:0014741 ! negative regulation of muscle hypertrophy +is_a: GO:0014745 ! negative regulation of muscle adaptation +is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy +relationship: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy +created_by: sl +creation_date: 2015-05-08T17:38:19Z + +[Term] +id: GO:1904206 +name: positive regulation of skeletal muscle hypertrophy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] +synonym: "activation of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] +synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] +is_a: GO:0014742 ! positive regulation of muscle hypertrophy +is_a: GO:0014744 ! positive regulation of muscle adaptation +is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014734 ! skeletal muscle hypertrophy +relationship: positively_regulates GO:0014734 ! skeletal muscle hypertrophy +created_by: sl +creation_date: 2015-05-08T17:38:25Z + +[Term] +id: GO:1904207 +name: regulation of chemokine (C-C motif) ligand 2 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24260297] +synonym: "regulation of CCL2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0090196 ! regulation of chemokine secretion +is_a: GO:2000341 ! regulation of chemokine (C-X-C motif) ligand 2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +relationship: regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +created_by: sl +creation_date: 2015-05-11T16:47:07Z + +[Term] +id: GO:1904208 +name: negative regulation of chemokine (C-C motif) ligand 2 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24260297] +synonym: "down regulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of CCL2 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of chemokine (C-C motif) ligand 2 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of CCL2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0090198 ! negative regulation of chemokine secretion +is_a: GO:1904207 ! regulation of chemokine (C-C motif) ligand 2 secretion +is_a: GO:2000342 ! negative regulation of chemokine (C-X-C motif) ligand 2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +relationship: negatively_regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +created_by: sl +creation_date: 2015-05-11T16:47:13Z + +[Term] +id: GO:1904209 +name: positive regulation of chemokine (C-C motif) ligand 2 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24260297] +synonym: "activation of CCL2 secretion" NARROW [GOC:TermGenie] +synonym: "activation of chemokine (C-C motif) ligand 2 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of CCL2 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of chemokine (C-C motif) ligand 2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0090197 ! positive regulation of chemokine secretion +is_a: GO:1904207 ! regulation of chemokine (C-C motif) ligand 2 secretion +is_a: GO:2000343 ! positive regulation of chemokine (C-X-C motif) ligand 2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +relationship: positively_regulates GO:0035926 ! chemokine (C-C motif) ligand 2 secretion +created_by: sl +creation_date: 2015-05-11T16:47:19Z + +[Term] +id: GO:1904210 +name: VCP-NPL4-UFD1 AAA ATPase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17000876] +synonym: "Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2015-05-14T10:34:36Z + +[Term] +id: GO:1904211 +name: membrane protein proteolysis involved in retrograde protein transport, ER to cytosol +namespace: biological_process +def: "Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22795130] +synonym: "intramembrane cleavage of ERAD substrate" BROAD [PMID:22795130] +synonym: "intramembrane proteolysis involved in ERAD" EXACT [PMID:22795130] +synonym: "membrane protein proteolysis involved in protein dislocation from ER" EXACT [GOC:TermGenie] +synonym: "membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol" EXACT [GOC:TermGenie] +synonym: "membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol" EXACT [GOC:TermGenie] +is_a: GO:0033619 ! membrane protein proteolysis +is_a: GO:0051603 ! proteolysis involved in cellular protein catabolic process +intersection_of: GO:0033619 ! membrane protein proteolysis +intersection_of: part_of GO:0030970 ! retrograde protein transport, ER to cytosol +relationship: part_of GO:0030970 ! retrograde protein transport, ER to cytosol +created_by: bf +creation_date: 2015-05-14T15:26:44Z + +[Term] +id: GO:1904212 +name: regulation of iodide transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of iodide transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +is_a: GO:1904201 ! regulation of iodide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904200 ! iodide transmembrane transport +relationship: regulates GO:1904200 ! iodide transmembrane transport +created_by: sl +creation_date: 2015-05-14T19:00:02Z + +[Term] +id: GO:1904213 +name: negative regulation of iodide transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +synonym: "down regulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +synonym: "downregulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +synonym: "inhibition of iodide transmembrane transport" NARROW [GOC:TermGenie] +is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport +is_a: GO:1904202 ! negative regulation of iodide transport +is_a: GO:1904212 ! regulation of iodide transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904200 ! iodide transmembrane transport +relationship: negatively_regulates GO:1904200 ! iodide transmembrane transport +created_by: sl +creation_date: 2015-05-14T19:00:08Z + +[Term] +id: GO:1904214 +name: positive regulation of iodide transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:20392814] +synonym: "activation of iodide transmembrane transport" NARROW [GOC:TermGenie] +synonym: "up regulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of iodide transmembrane transport" EXACT [GOC:TermGenie] +is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport +is_a: GO:1904203 ! positive regulation of iodide transport +is_a: GO:1904212 ! regulation of iodide transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904200 ! iodide transmembrane transport +relationship: positively_regulates GO:1904200 ! iodide transmembrane transport +created_by: sl +creation_date: 2015-05-14T19:00:14Z + +[Term] +id: GO:1904215 +name: regulation of protein import into chloroplast stroma +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma." [GO_REF:0000058, GOC:TermGenie, PMID:25901327] +synonym: "regulation of chloroplast stroma protein import" EXACT [GOC:TermGenie] +synonym: "regulation of protein transport into chloroplast stroma" EXACT [GOC:TermGenie] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:1903533 ! regulation of protein targeting +is_a: GO:1904589 ! regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045037 ! protein import into chloroplast stroma +relationship: regulates GO:0045037 ! protein import into chloroplast stroma +created_by: tb +creation_date: 2015-05-15T00:47:48Z + +[Term] +id: GO:1904216 +name: positive regulation of protein import into chloroplast stroma +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma." [GO_REF:0000058, GOC:TermGenie, PMID:25901327] +synonym: "activation of chloroplast stroma protein import" NARROW [GOC:TermGenie] +synonym: "activation of protein import into chloroplast stroma" NARROW [GOC:TermGenie] +synonym: "activation of protein transport into chloroplast stroma" NARROW [GOC:TermGenie] +synonym: "positive regulation of chloroplast stroma protein import" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein transport into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "up regulation of chloroplast stroma protein import" EXACT [GOC:TermGenie] +synonym: "up regulation of protein import into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "up regulation of protein transport into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "up-regulation of chloroplast stroma protein import" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein import into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein transport into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "upregulation of chloroplast stroma protein import" EXACT [GOC:TermGenie] +synonym: "upregulation of protein import into chloroplast stroma" EXACT [GOC:TermGenie] +synonym: "upregulation of protein transport into chloroplast stroma" EXACT [GOC:TermGenie] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1904215 ! regulation of protein import into chloroplast stroma +is_a: GO:1904591 ! positive regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045037 ! protein import into chloroplast stroma +relationship: positively_regulates GO:0045037 ! protein import into chloroplast stroma +created_by: tb +creation_date: 2015-05-15T00:47:55Z + +[Term] +id: GO:1904217 +name: regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate +synonym: "regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of serine exchange enzyme" BROAD [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +relationship: regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:18:23Z + +[Term] +id: GO:1904218 +name: negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate +synonym: "down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDP-diglyceride:serine phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine synthase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PS synthase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of PS synthase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904217 ! regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +relationship: negatively_regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:18:29Z + +[Term] +id: GO:1904219 +name: positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate +synonym: "activation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDP-diglyceride-L-serine phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDP-diglyceride:serine phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDP-diglycerine-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CDPdiglyceride-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylserine synthase activity" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylserine synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of PS synthase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of PS synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of PS synthase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904217 ! regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +relationship: positively_regulates GO:0003882 ! CDP-diacylglycerol-serine O-phosphatidyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:18:35Z + +[Term] +id: GO:1904220 +name: regulation of serine C-palmitoyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability +synonym: "regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "regulation of serine palmitoyltransferase" BROAD [GOC:TermGenie] +synonym: "regulation of SPT" RELATED [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004758 ! serine C-palmitoyltransferase activity +relationship: regulates GO:0004758 ! serine C-palmitoyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:27:33Z + +[Term] +id: GO:1904221 +name: negative regulation of serine C-palmitoyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability +synonym: "down regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "down regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of SPT" RELATED [GOC:TermGenie] +synonym: "down-regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of SPT" RELATED [GOC:TermGenie] +synonym: "downregulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "downregulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of SPT" RELATED [GOC:TermGenie] +synonym: "inhibition of 3-oxosphinganine synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of serine C-palmitoyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of SPT" RELATED [GOC:TermGenie] +synonym: "negative regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of SPT" RELATED [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904220 ! regulation of serine C-palmitoyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004758 ! serine C-palmitoyltransferase activity +relationship: negatively_regulates GO:0004758 ! serine C-palmitoyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:27:39Z + +[Term] +id: GO:1904222 +name: positive regulation of serine C-palmitoyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] +comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability +synonym: "activation of 3-oxosphinganine synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" NARROW [GOC:TermGenie] +synonym: "activation of serine C-palmitoyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of SPT" RELATED [GOC:TermGenie] +synonym: "positive regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of SPT" RELATED [GOC:TermGenie] +synonym: "up regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "up regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of SPT" RELATED [GOC:TermGenie] +synonym: "up-regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of SPT" RELATED [GOC:TermGenie] +synonym: "upregulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] +synonym: "upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] +synonym: "upregulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of SPT" RELATED [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904220 ! regulation of serine C-palmitoyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004758 ! serine C-palmitoyltransferase activity +relationship: positively_regulates GO:0004758 ! serine C-palmitoyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:27:45Z + +[Term] +id: GO:1904223 +name: regulation of glucuronosyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20610558] +comment: i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species +synonym: "regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015020 ! glucuronosyltransferase activity +relationship: regulates GO:0015020 ! glucuronosyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:44:20Z + +[Term] +id: GO:1904224 +name: negative regulation of glucuronosyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20610558] +comment: i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species +synonym: "down regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "down regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "down regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "down regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "down regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "down-regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "downregulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "downregulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of GT activity" EXACT [GOC:TermGenie] +synonym: "downregulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "downregulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "downregulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "downregulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "inhibition of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP glucuronic acid transferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDPGA transferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDPGA-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "inhibition of UDPGT activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine 5'-diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphate glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "negative regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904223 ! regulation of glucuronosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015020 ! glucuronosyltransferase activity +relationship: negatively_regulates GO:0015020 ! glucuronosyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:44:26Z + +[Term] +id: GO:1904225 +name: positive regulation of glucuronosyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20610558] +comment: i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species +synonym: "activation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of GT activity" NARROW [GOC:TermGenie] +synonym: "activation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "activation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP glucuronic acid transferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" NARROW [GOC:TermGenie] +synonym: "activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDPGA transferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDPGA-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "activation of UDPGT activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine 5'-diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphate glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "positive regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "up regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "up regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "up regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "up regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of GT activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "up-regulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 1-naphthol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 1-naphthol-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 17-OH steroid UDPGT activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 3-OH androgenic UDPGT activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 4-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of 4-nitrophenol UDPGT activity" NARROW [GOC:TermGenie] +synonym: "upregulation of bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of bilirubin monoglucuronide glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of bilirubin UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of bilirubin UDPGT activity" NARROW [GOC:TermGenie] +synonym: "upregulation of bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of ciramadol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of estriol UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of estrone UDPglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of GT activity" EXACT [GOC:TermGenie] +synonym: "upregulation of morphine glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of p-nitrophenol UDP-glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of p-nitrophenylglucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of p-phenylphenol glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of phenyl-UDP-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of PNP-UDPGT" RELATED [GOC:TermGenie] +synonym: "upregulation of pnp-UDPGT activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDP glucuronic acid transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDP glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDP glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [GOC:TermGenie] +synonym: "upregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDP-glucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDP-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDPGA transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDPGA-glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW [GOC:TermGenie] +synonym: "upregulation of UDPGT activity" EXACT [GOC:TermGenie] +synonym: "upregulation of uridine 5'-diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of uridine diphosphate glucuronyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of uridine diphosphoglucuronyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904223 ! regulation of glucuronosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015020 ! glucuronosyltransferase activity +relationship: positively_regulates GO:0015020 ! glucuronosyltransferase activity +created_by: rl +creation_date: 2015-05-15T08:44:32Z + +[Term] +id: GO:1904226 +name: regulation of glycogen synthase activity, transferring glucose-1-phosphate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17569761] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +relationship: regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +created_by: rl +creation_date: 2015-05-15T09:23:08Z + +[Term] +id: GO:1904227 +name: negative regulation of glycogen synthase activity, transferring glucose-1-phosphate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17569761] +synonym: "down regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +synonym: "downregulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +synonym: "inhibition of glycogen synthase activity, transferring glucose-1-phosphate" NARROW [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904226 ! regulation of glycogen synthase activity, transferring glucose-1-phosphate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +relationship: negatively_regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +created_by: rl +creation_date: 2015-05-15T09:23:14Z + +[Term] +id: GO:1904228 +name: positive regulation of glycogen synthase activity, transferring glucose-1-phosphate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17569761] +synonym: "activation of glycogen synthase activity, transferring glucose-1-phosphate" NARROW [GOC:TermGenie] +synonym: "up regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +synonym: "upregulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904226 ! regulation of glycogen synthase activity, transferring glucose-1-phosphate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +relationship: positively_regulates GO:0061547 ! glycogen synthase activity, transferring glucose-1-phosphate +created_by: rl +creation_date: 2015-05-15T09:23:20Z + +[Term] +id: GO:1904229 +name: regulation of succinate dehydrogenase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinic dehydrogenase activity" BROAD [GOC:TermGenie] +synonym: "regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000104 ! succinate dehydrogenase activity +relationship: regulates GO:0000104 ! succinate dehydrogenase activity +created_by: rl +creation_date: 2015-05-15T09:51:08Z + +[Term] +id: GO:1904230 +name: negative regulation of succinate dehydrogenase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "down regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of fumarate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of fumarate reductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of fumaric hydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinate oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinate:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinate:acceptor oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinic acid dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinodehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of succinyl dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1904229 ! regulation of succinate dehydrogenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000104 ! succinate dehydrogenase activity +relationship: negatively_regulates GO:0000104 ! succinate dehydrogenase activity +created_by: rl +creation_date: 2015-05-15T09:51:14Z + +[Term] +id: GO:1904231 +name: positive regulation of succinate dehydrogenase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "activation of fumarate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of fumarate reductase activity" NARROW [GOC:TermGenie] +synonym: "activation of fumaric hydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinate dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinate oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinate:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinate:acceptor oxidoreductase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinic acid dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinodehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "activation of succinyl dehydrogenase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of fumarate reductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1904229 ! regulation of succinate dehydrogenase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000104 ! succinate dehydrogenase activity +relationship: positively_regulates GO:0000104 ! succinate dehydrogenase activity +created_by: rl +creation_date: 2015-05-15T09:51:20Z + +[Term] +id: GO:1904232 +name: regulation of aconitate hydratase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aconitate hydratase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "regulation of citrate hydro-lyase activity" BROAD [GOC:TermGenie] +synonym: "regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +is_a: GO:0051339 ! regulation of lyase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003994 ! aconitate hydratase activity +relationship: regulates GO:0003994 ! aconitate hydratase activity +created_by: rl +creation_date: 2015-05-15T09:55:17Z + +[Term] +id: GO:1904233 +name: negative regulation of aconitate hydratase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "down regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of aconitase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of aconitate hydratase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cis-aconitase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of citrate(isocitrate) hydro-lyase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +is_a: GO:0051350 ! negative regulation of lyase activity +is_a: GO:1904232 ! regulation of aconitate hydratase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003994 ! aconitate hydratase activity +relationship: negatively_regulates GO:0003994 ! aconitate hydratase activity +created_by: rl +creation_date: 2015-05-15T09:55:23Z + +[Term] +id: GO:1904234 +name: positive regulation of aconitate hydratase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] +synonym: "activation of aconitase activity" NARROW [GOC:TermGenie] +synonym: "activation of aconitate hydratase activity" NARROW [GOC:TermGenie] +synonym: "activation of cis-aconitase activity" NARROW [GOC:TermGenie] +synonym: "activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" NARROW [GOC:TermGenie] +synonym: "activation of citrate(isocitrate) hydro-lyase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aconitase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aconitate hydratase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cis-aconitase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] +is_a: GO:0051349 ! positive regulation of lyase activity +is_a: GO:1904232 ! regulation of aconitate hydratase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003994 ! aconitate hydratase activity +relationship: positively_regulates GO:0003994 ! aconitate hydratase activity +created_by: rl +creation_date: 2015-05-15T09:55:29Z + +[Term] +id: GO:1904235 +name: regulation of substrate-dependent cell migration, cell attachment to substrate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate." [GO_REF:0000058, GOC:TermGenie, PMID:25834989] +synonym: "regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +is_a: GO:0010810 ! regulation of cell-substrate adhesion +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +relationship: regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +created_by: pga +creation_date: 2015-05-15T13:29:59Z + +[Term] +id: GO:1904236 +name: negative regulation of substrate-dependent cell migration, cell attachment to substrate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate." [GO_REF:0000058, GOC:TermGenie, PMID:25834989] +synonym: "down regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "down regulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "down-regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "down-regulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "downregulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "downregulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "inhibition of substrate-bound cell migration, cell attachment to substrate" NARROW [GOC:TermGenie] +synonym: "inhibition of substrate-dependent cell migration, cell attachment to substrate" NARROW [GOC:TermGenie] +synonym: "negative regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +is_a: GO:0010812 ! negative regulation of cell-substrate adhesion +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:1904235 ! regulation of substrate-dependent cell migration, cell attachment to substrate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +relationship: negatively_regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +created_by: pga +creation_date: 2015-05-15T13:30:05Z + +[Term] +id: GO:1904237 +name: positive regulation of substrate-dependent cell migration, cell attachment to substrate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate." [GO_REF:0000058, GOC:TermGenie, PMID:25834989] +synonym: "activation of substrate-bound cell migration, cell attachment to substrate" NARROW [GOC:TermGenie] +synonym: "activation of substrate-dependent cell migration, cell attachment to substrate" NARROW [GOC:TermGenie] +synonym: "positive regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "up regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "up regulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "up-regulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "up-regulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "upregulation of substrate-bound cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +synonym: "upregulation of substrate-dependent cell migration, cell attachment to substrate" EXACT [GOC:TermGenie] +is_a: GO:0010811 ! positive regulation of cell-substrate adhesion +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:1904235 ! regulation of substrate-dependent cell migration, cell attachment to substrate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +relationship: positively_regulates GO:0006931 ! substrate-dependent cell migration, cell attachment to substrate +created_by: pga +creation_date: 2015-05-15T13:30:11Z + +[Term] +id: GO:1904238 +name: pericyte cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell." [GO_REF:0000086, GOC:dph, GOC:TermGenie, PMID:23868830] +is_a: GO:0030154 ! cell differentiation +created_by: dph +creation_date: 2015-05-15T14:50:13Z + +[Term] +id: GO:1904239 +name: regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +relationship: regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +created_by: bf +creation_date: 2015-05-18T09:50:21Z + +[Term] +id: GO:1904240 +name: negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17000876] +synonym: "down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "down regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "downregulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of p97-Ufd1-Npl4 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of p97-Ufd1-Npl4 complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of VCP-NPL4-UFD1 AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of VCP-NPL4-UFD1 AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1904239 ! regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +relationship: negatively_regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +created_by: bf +creation_date: 2015-05-18T09:50:27Z + +[Term] +id: GO:1904241 +name: positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "activation of p97-Ufd1-Npl4 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of p97-Ufd1-Npl4 complex formation" NARROW [GOC:TermGenie] +synonym: "activation of VCP-NPL4-UFD1 AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of VCP-NPL4-UFD1 AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "up regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation" NARROW [GOC:TermGenie] +synonym: "upregulation of p97-Ufd1-Npl4 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of p97-Ufd1-Npl4 complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of VCP-NPL4-UFD1 AAA ATPase complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1904239 ! regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +relationship: positively_regulates GO:1904210 ! VCP-NPL4-UFD1 AAA ATPase complex assembly +created_by: bf +creation_date: 2015-05-18T09:50:34Z + +[Term] +id: GO:1904242 +name: regulation of pancreatic trypsinogen secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion." [GO_REF:0000058, GOC:TermGenie, PMID:12771515] +synonym: "regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +is_a: GO:0050708 ! regulation of protein secretion +is_a: GO:0090186 ! regulation of pancreatic juice secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990747 ! pancreatic trypsinogen secretion +relationship: regulates GO:1990747 ! pancreatic trypsinogen secretion +created_by: sl +creation_date: 2015-05-18T19:49:20Z + +[Term] +id: GO:1904243 +name: negative regulation of pancreatic trypsinogen secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion." [GO_REF:0000058, GOC:TermGenie, PMID:12771515] +synonym: "down regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "down regulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "down-regulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "downregulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of pancreatic trypsinogen release" NARROW [GOC:TermGenie] +synonym: "inhibition of pancreatic trypsinogen secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:0090188 ! negative regulation of pancreatic juice secretion +is_a: GO:1904242 ! regulation of pancreatic trypsinogen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990747 ! pancreatic trypsinogen secretion +relationship: negatively_regulates GO:1990747 ! pancreatic trypsinogen secretion +created_by: sl +creation_date: 2015-05-18T19:49:27Z + +[Term] +id: GO:1904244 +name: positive regulation of pancreatic trypsinogen secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion." [GO_REF:0000058, GOC:TermGenie, PMID:12771515] +synonym: "activation of pancreatic trypsinogen release" NARROW [GOC:TermGenie] +synonym: "activation of pancreatic trypsinogen secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "up regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "up regulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic trypsinogen release" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic trypsinogen secretion" EXACT [GOC:TermGenie] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:0090187 ! positive regulation of pancreatic juice secretion +is_a: GO:1904242 ! regulation of pancreatic trypsinogen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990747 ! pancreatic trypsinogen secretion +relationship: positively_regulates GO:1990747 ! pancreatic trypsinogen secretion +created_by: sl +creation_date: 2015-05-18T19:49:32Z + +[Term] +id: GO:1904245 +name: regulation of polynucleotide adenylyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:19460348] +synonym: "regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004652 ! polynucleotide adenylyltransferase activity +relationship: regulates GO:0004652 ! polynucleotide adenylyltransferase activity +created_by: kmv +creation_date: 2015-05-19T14:47:20Z + +[Term] +id: GO:1904246 +name: negative regulation of polynucleotide adenylyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:19460348] +synonym: "down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "down regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "down-regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "downregulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of AMP polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP-polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NTP polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of poly(A) hydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of poly(A) polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of poly(A) synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of poly-A polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polyadenylate nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polyadenylate polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polyadenylate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polyadenylic acid polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polyadenylic polymerase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA adenylating enzyme activity" NARROW [GOC:TermGenie] +synonym: "inhibition of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "inhibition of terminal riboadenylate transferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "negative regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904245 ! regulation of polynucleotide adenylyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004652 ! polynucleotide adenylyltransferase activity +relationship: negatively_regulates GO:0004652 ! polynucleotide adenylyltransferase activity +created_by: kmv +creation_date: 2015-05-19T14:47:26Z + +[Term] +id: GO:1904247 +name: positive regulation of polynucleotide adenylyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:19460348] +synonym: "activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of AMP polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP-polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP:polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP:polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of NTP polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of poly(A) hydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of poly(A) polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of poly(A) synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of poly-A polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of polyadenylate nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of polyadenylate polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of polyadenylate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of polyadenylic acid polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of polyadenylic polymerase activity" NARROW [GOC:TermGenie] +synonym: "activation of polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of RNA adenylating enzyme activity" NARROW [GOC:TermGenie] +synonym: "activation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "activation of terminal riboadenylate transferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "positive regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "up regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "up-regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NTP polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of poly-A polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] +synonym: "upregulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904245 ! regulation of polynucleotide adenylyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004652 ! polynucleotide adenylyltransferase activity +relationship: positively_regulates GO:0004652 ! polynucleotide adenylyltransferase activity +created_by: kmv +creation_date: 2015-05-19T14:47:32Z + +[Term] +id: GO:1904248 +name: regulation of age-related resistance +namespace: biological_process +def: "Any process that modulates the extent of age-related resistance." [GO_REF:0000058, GOC:TermGenie, PMID:19694953] +synonym: "regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "regulation of ARR" EXACT [GOC:TermGenie] +synonym: "regulation of developmental resistance" BROAD [GOC:TermGenie] +synonym: "regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "regulation of ontogenic resistance" BROAD [GOC:TermGenie] +synonym: "regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090644 ! age-related resistance +relationship: regulates GO:0090644 ! age-related resistance +created_by: tb +creation_date: 2015-05-19T20:19:58Z + +[Term] +id: GO:1904249 +name: negative regulation of age-related resistance +namespace: biological_process +def: "Any process that stops, prevents or reduces the extent of age-related resistance." [GO_REF:0000058, GOC:TermGenie, PMID:19694953] +synonym: "down regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "down regulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "down regulation of ARR" EXACT [GOC:TermGenie] +synonym: "down regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "down regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "down regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "down-regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "down-regulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "down-regulation of ARR" EXACT [GOC:TermGenie] +synonym: "down-regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "down-regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "down-regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "downregulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "downregulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "downregulation of ARR" EXACT [GOC:TermGenie] +synonym: "downregulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "downregulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "downregulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "inhibition of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "inhibition of age-related resistance" NARROW [GOC:TermGenie] +synonym: "inhibition of ARR" NARROW [GOC:TermGenie] +synonym: "inhibition of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "inhibition of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "inhibition of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "negative regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "negative regulation of ARR" EXACT [GOC:TermGenie] +synonym: "negative regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "negative regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "negative regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1904248 ! regulation of age-related resistance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090644 ! age-related resistance +relationship: negatively_regulates GO:0090644 ! age-related resistance +created_by: tb +creation_date: 2015-05-19T20:20:05Z + +[Term] +id: GO:1904250 +name: positive regulation of age-related resistance +namespace: biological_process +def: "Any process that activates or increases the extent of age-related resistance." [GO_REF:0000058, GOC:TermGenie, PMID:19694953] +synonym: "activation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "activation of age-related resistance" NARROW [GOC:TermGenie] +synonym: "activation of ARR" NARROW [GOC:TermGenie] +synonym: "activation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "activation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "activation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "positive regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "positive regulation of ARR" EXACT [GOC:TermGenie] +synonym: "positive regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "positive regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "positive regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "up regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "up regulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "up regulation of ARR" EXACT [GOC:TermGenie] +synonym: "up regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "up regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "up regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "up-regulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "up-regulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "up-regulation of ARR" EXACT [GOC:TermGenie] +synonym: "up-regulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "up-regulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "up-regulation of senescence-induced resistance" NARROW [GOC:TermGenie] +synonym: "upregulation of adult seedling resistance" NARROW [GOC:TermGenie] +synonym: "upregulation of age-related resistance" EXACT [GOC:TermGenie] +synonym: "upregulation of ARR" EXACT [GOC:TermGenie] +synonym: "upregulation of flowering-induced resistance" NARROW [GOC:TermGenie] +synonym: "upregulation of mature seedling resistance" NARROW [GOC:TermGenie] +synonym: "upregulation of senescence-induced resistance" NARROW [GOC:TermGenie] +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1904248 ! regulation of age-related resistance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090644 ! age-related resistance +relationship: positively_regulates GO:0090644 ! age-related resistance +created_by: tb +creation_date: 2015-05-19T20:20:11Z + +[Term] +id: GO:1904251 +name: regulation of bile acid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] +synonym: "regulation of bile acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019218 ! regulation of steroid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008206 ! bile acid metabolic process +relationship: regulates GO:0008206 ! bile acid metabolic process +created_by: bf +creation_date: 2015-05-20T11:04:28Z + +[Term] +id: GO:1904252 +name: negative regulation of bile acid metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] +synonym: "down regulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of bile acid metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of bile acid metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of bile acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0045939 ! negative regulation of steroid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1904251 ! regulation of bile acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008206 ! bile acid metabolic process +relationship: negatively_regulates GO:0008206 ! bile acid metabolic process +created_by: bf +creation_date: 2015-05-20T11:04:35Z + +[Term] +id: GO:1904253 +name: positive regulation of bile acid metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] +synonym: "activation of bile acid metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of bile acid metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of bile acid metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of bile acid metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of bile acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0045940 ! positive regulation of steroid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1904251 ! regulation of bile acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008206 ! bile acid metabolic process +relationship: positively_regulates GO:0008206 ! bile acid metabolic process +created_by: bf +creation_date: 2015-05-20T11:04:40Z + +[Term] +id: GO:1904254 +name: regulation of iron ion transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of iron channel activity" EXACT [] +synonym: "regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:0034759 ! regulation of iron ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005381 ! iron ion transmembrane transporter activity +relationship: regulates GO:0005381 ! iron ion transmembrane transporter activity +created_by: kom +creation_date: 2015-05-20T14:05:00Z + +[Term] +id: GO:1904255 +name: negative regulation of iron ion transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "down regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of iron cation channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of iron channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of iron-specific channel activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of iron channel activity" EXACT [] +synonym: "negative regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0034760 ! negative regulation of iron ion transmembrane transport +is_a: GO:1904254 ! regulation of iron ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005381 ! iron ion transmembrane transporter activity +relationship: negatively_regulates GO:0005381 ! iron ion transmembrane transporter activity +created_by: kom +creation_date: 2015-05-20T14:05:06Z + +[Term] +id: GO:1904256 +name: positive regulation of iron ion transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:15514116] +synonym: "activation of iron cation channel activity" NARROW [GOC:TermGenie] +synonym: "activation of iron channel activity" NARROW [GOC:TermGenie] +synonym: "activation of iron-specific channel activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of iron channel activity" EXACT [] +synonym: "positive regulation of iron transmembrane transporter activity" EXACT [] +synonym: "positive regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of iron-specific channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of iron cation channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of iron channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of iron-specific channel activity" EXACT [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:0034761 ! positive regulation of iron ion transmembrane transport +is_a: GO:1904254 ! regulation of iron ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005381 ! iron ion transmembrane transporter activity +relationship: positively_regulates GO:0005381 ! iron ion transmembrane transporter activity +created_by: kom +creation_date: 2015-05-20T14:05:12Z + +[Term] +id: GO:1904257 +name: zinc ion import into Golgi apparatus +namespace: biological_process +def: "The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus." [GO_REF:0000075, GOC:TermGenie, PMID:25732056] +synonym: "zinc II ion import across Golgi membrane" EXACT [] +synonym: "zinc ion import across Golgi membrane" EXACT [] +synonym: "zinc ion import into Golgi membrane" RELATED [] +synonym: "zinc(2+) import across Golgi membrane" EXACT [] +is_a: GO:0062111 ! zinc ion import into organelle +created_by: tb +creation_date: 2015-05-20T19:56:18Z + +[Term] +id: GO:1904258 +name: nuclear dicing body assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body." [GO_REF:0000079, GOC:TermGenie, PMID:25902521] +synonym: "D body assembly" EXACT [GOC:TermGenie] +synonym: "D body formation" EXACT [GOC:TermGenie] +synonym: "nuclear dicing body formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0030575 ! nuclear body organization +created_by: lr +creation_date: 2015-05-20T20:48:07Z + +[Term] +id: GO:1904259 +name: regulation of basement membrane assembly involved in embryonic body morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:0110011 ! regulation of basement membrane organization +is_a: GO:1901201 ! regulation of extracellular matrix assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +relationship: regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +created_by: als +creation_date: 2015-05-21T09:20:43Z + +[Term] +id: GO:1904260 +name: negative regulation of basement membrane assembly involved in embryonic body morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118] +synonym: "down regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of basement membrane assembly involved in embryonic body morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1901202 ! negative regulation of extracellular matrix assembly +is_a: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +relationship: negatively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +created_by: als +creation_date: 2015-05-21T09:20:49Z + +[Term] +id: GO:1904261 +name: positive regulation of basement membrane assembly involved in embryonic body morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23940118] +synonym: "activation of basement membrane assembly involved in embryonic body morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of basement membrane assembly involved in embryonic body morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:1901203 ! positive regulation of extracellular matrix assembly +is_a: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +relationship: positively_regulates GO:2001197 ! basement membrane assembly involved in embryonic body morphogenesis +created_by: als +creation_date: 2015-05-21T09:20:55Z + +[Term] +id: GO:1904262 +name: negative regulation of TORC1 signaling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling." [GO_REF:0000058, GOC:TermGenie, PMID:25366275] +synonym: "down regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "down regulation of TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "down-regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "down-regulation of TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "downregulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "downregulation of TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "inhibition of TORC1 signal transduction" NARROW [GOC:TermGenie] +synonym: "inhibition of TORC1 signaling" NARROW [GOC:TermGenie] +synonym: "negative regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +is_a: GO:0032007 ! negative regulation of TOR signaling +is_a: GO:1903432 ! regulation of TORC1 signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038202 ! TORC1 signaling +relationship: negatively_regulates GO:0038202 ! TORC1 signaling +created_by: lb +creation_date: 2015-05-27T13:13:04Z + +[Term] +id: GO:1904263 +name: positive regulation of TORC1 signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of TORC1 signaling." [GO_REF:0000058, GOC:TermGenie, PMID:25366275] +synonym: "activation of TORC1 signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of TORC1 signaling" NARROW [GOC:TermGenie] +synonym: "positive regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of TORC1 signaling" EXACT [GOC:TermGenie] +is_a: GO:0032008 ! positive regulation of TOR signaling +is_a: GO:1903432 ! regulation of TORC1 signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038202 ! TORC1 signaling +relationship: positively_regulates GO:0038202 ! TORC1 signaling +created_by: lb +creation_date: 2015-05-27T13:13:10Z + +[Term] +id: GO:1904266 +name: regulation of Schwann cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:16203995] +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:1900147 ! regulation of Schwann cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990751 ! Schwann cell chemotaxis +relationship: regulates GO:1990751 ! Schwann cell chemotaxis +created_by: sl +creation_date: 2015-05-28T17:47:41Z + +[Term] +id: GO:1904267 +name: negative regulation of Schwann cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:16203995] +synonym: "down regulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +synonym: "downregulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +synonym: "inhibition of Schwann cell chemotaxis" NARROW [GOC:TermGenie] +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:1900148 ! negative regulation of Schwann cell migration +is_a: GO:1904266 ! regulation of Schwann cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990751 ! Schwann cell chemotaxis +relationship: negatively_regulates GO:1990751 ! Schwann cell chemotaxis +created_by: sl +creation_date: 2015-05-28T17:47:48Z + +[Term] +id: GO:1904268 +name: positive regulation of Schwann cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:16203995] +synonym: "activation of Schwann cell chemotaxis" NARROW [GOC:TermGenie] +synonym: "up regulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +synonym: "upregulation of Schwann cell chemotaxis" EXACT [GOC:TermGenie] +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1900149 ! positive regulation of Schwann cell migration +is_a: GO:1904266 ! regulation of Schwann cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990751 ! Schwann cell chemotaxis +relationship: positively_regulates GO:1990751 ! Schwann cell chemotaxis +created_by: sl +creation_date: 2015-05-28T17:47:55Z + +[Term] +id: GO:1904269 +name: cell leading edge cell cortex +namespace: cellular_component +def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030] +synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie] +synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie] +synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie] +synonym: "cell periphery of cell leading edge" RELATED [GOC:TermGenie] +synonym: "cell periphery of front of cell" RELATED [GOC:TermGenie] +synonym: "cell periphery of leading edge of cell" RELATED [GOC:TermGenie] +synonym: "peripheral cytoplasm of cell leading edge" RELATED [GOC:TermGenie] +synonym: "peripheral cytoplasm of front of cell" RELATED [GOC:TermGenie] +synonym: "peripheral cytoplasm of leading edge of cell" RELATED [GOC:TermGenie] +is_a: GO:0099738 ! cell cortex region +intersection_of: GO:0099738 ! cell cortex region +intersection_of: part_of GO:0031252 ! cell leading edge +relationship: part_of GO:0031252 ! cell leading edge +created_by: kmv +creation_date: 2015-05-28T19:16:03Z + +[Term] +id: GO:1904270 +name: pyroptosome complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex." [GO_REF:0000079, GOC:TermGenie, PMID:17964261] +synonym: "ASC pyroptosome assembly" EXACT [GOC:TermGenie] +synonym: "ASC pyroptosome formation" EXACT [GOC:TermGenie] +synonym: "pyroptosome complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: lb +creation_date: 2015-05-29T08:25:45Z + +[Term] +id: GO:1904271 +name: L-proline import across plasma membrane +namespace: biological_process +alt_id: GO:1903809 +def: "The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:kmv, GOC:TermGenie, PMID:21097500] +synonym: "L-proline import into cell" EXACT [] +is_a: GO:1904555 ! L-proline transmembrane transport +is_a: GO:1905647 ! proline import across plasma membrane +created_by: mah +creation_date: 2015-01-16T14:36:01Z + +[Term] +id: GO:1904272 +name: L-tryptophan import across plasma membrane +namespace: biological_process +def: "The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:kmv, GOC:TermGenie, PMID:21097500] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1904556 ! L-tryptophan transmembrane transport +created_by: kmv +creation_date: 2015-05-29T13:39:27Z + +[Term] +id: GO:1904273 +name: L-alanine import across plasma membrane +namespace: biological_process +def: "The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:kmv, GOC:TermGenie, PMID:21097500] +is_a: GO:0089718 ! amino acid import across plasma membrane +is_a: GO:1904557 ! L-alanine transmembrane transport + +[Term] +id: GO:1904274 +name: tricellular tight junction assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction." [GO_REF:0000079, GOC:mr, GOC:TermGenie, PMID:22640933, PMID:25097825, PMID:4203962] +synonym: "tricellular tight junction formation" EXACT [GOC:TermGenie] +is_a: GO:0120192 ! tight junction assembly +created_by: mr +creation_date: 2015-05-29T16:31:00Z + +[Term] +id: GO:1904275 +name: tricellular tight junction disassembly +namespace: biological_process +def: "The disaggregation of a tricellular tight junction into its constituent components." [GO_REF:0000079, GOC:mr, GOC:TermGenie, PMID:22640933, PMID:25097825, PMID:4203962] +is_a: GO:1905071 ! tight junction disassembly +created_by: mr +creation_date: 2015-05-29T16:31:06Z + +[Term] +id: GO:1904276 +name: regulation of wax biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of wax biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24692420] +synonym: "regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "regulation of wax synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009889 ! regulation of biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010025 ! wax biosynthetic process +relationship: regulates GO:0010025 ! wax biosynthetic process +created_by: tb +creation_date: 2015-06-03T17:20:06Z + +[Term] +id: GO:1904277 +name: negative regulation of wax biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24692420] +synonym: "down regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "down regulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of wax formation" EXACT [GOC:TermGenie] +synonym: "downregulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of wax anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of wax biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of wax biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of wax formation" NARROW [GOC:TermGenie] +synonym: "inhibition of wax synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of wax synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009890 ! negative regulation of biosynthetic process +is_a: GO:1904276 ! regulation of wax biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010025 ! wax biosynthetic process +relationship: negatively_regulates GO:0010025 ! wax biosynthetic process +created_by: tb +creation_date: 2015-06-03T17:20:13Z + +[Term] +id: GO:1904278 +name: positive regulation of wax biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of wax biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24692420] +synonym: "activation of wax anabolism" NARROW [GOC:TermGenie] +synonym: "activation of wax biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of wax biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of wax formation" NARROW [GOC:TermGenie] +synonym: "activation of wax synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "up regulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of wax formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of wax synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of wax anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of wax biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of wax biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of wax formation" EXACT [GOC:TermGenie] +synonym: "upregulation of wax synthesis" EXACT [GOC:TermGenie] +is_a: GO:0009891 ! positive regulation of biosynthetic process +is_a: GO:1904276 ! regulation of wax biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010025 ! wax biosynthetic process +relationship: positively_regulates GO:0010025 ! wax biosynthetic process +created_by: tb +creation_date: 2015-06-03T17:20:19Z + +[Term] +id: GO:1904279 +name: regulation of transcription by RNA polymerase V +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V." [GO_REF:0000058, GOC:TermGenie, PMID:24726328] +synonym: "regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "regulation of transcription from RNA polymerase V promoter" EXACT [] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001060 ! transcription by RNA polymerase V +relationship: regulates GO:0001060 ! transcription by RNA polymerase V +created_by: tb +creation_date: 2015-06-03T22:01:47Z + +[Term] +id: GO:1904280 +name: negative regulation of transcription by RNA polymerase V +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V." [GO_REF:0000058, GOC:TermGenie, PMID:24726328] +synonym: "down regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of transcription from RNA pol V promoter" NARROW [GOC:TermGenie] +synonym: "inhibition of transcription from RNA polymerase V promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of transcription from RNA polymerase V promoter" EXACT [] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:1904279 ! regulation of transcription by RNA polymerase V +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001060 ! transcription by RNA polymerase V +relationship: negatively_regulates GO:0001060 ! transcription by RNA polymerase V +created_by: tb +creation_date: 2015-06-03T22:01:54Z + +[Term] +id: GO:1904281 +name: positive regulation of transcription by RNA polymerase V +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V." [GO_REF:0000058, GOC:TermGenie, PMID:24726328] +synonym: "activation of transcription from RNA pol V promoter" NARROW [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase V promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase V promoter" EXACT [] +synonym: "up regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA pol V promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase V promoter" EXACT [GOC:TermGenie] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:1904279 ! regulation of transcription by RNA polymerase V +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001060 ! transcription by RNA polymerase V +relationship: positively_regulates GO:0001060 ! transcription by RNA polymerase V +created_by: tb +creation_date: 2015-06-03T22:02:00Z + +[Term] +id: GO:1904282 +name: regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24643698] +synonym: "regulation of antigen presentation, endogenous peptide antigen" BROAD [GOC:TermGenie] +synonym: "regulation of antigen processing, endogenous antigen via major histocompatibility complex class I" BROAD [GOC:TermGenie] +synonym: "regulation of antigen processing, endogenous antigen via MHC class I" BROAD [GOC:TermGenie] +synonym: "regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +is_a: GO:0002589 ! regulation of antigen processing and presentation of peptide antigen via MHC class I +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +relationship: regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +created_by: rl +creation_date: 2015-06-04T12:05:28Z + +[Term] +id: GO:1904283 +name: negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24643698] +synonym: "down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "down regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "down-regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "downregulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I" NARROW [GOC:TermGenie] +synonym: "inhibition of endogenous peptide antigen processing and presentation via MHC class I" NARROW [GOC:TermGenie] +synonym: "negative regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +is_a: GO:0002590 ! negative regulation of antigen processing and presentation of peptide antigen via MHC class I +is_a: GO:1904282 ! regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +relationship: negatively_regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +created_by: rl +creation_date: 2015-06-04T12:05:34Z + +[Term] +id: GO:1904284 +name: positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:24643698] +synonym: "activation of antigen processing and presentation of endogenous peptide antigen via MHC class I" NARROW [GOC:TermGenie] +synonym: "activation of endogenous peptide antigen processing and presentation via MHC class I" NARROW [GOC:TermGenie] +synonym: "positive regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "up regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "up regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "up-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "up-regulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +synonym: "upregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I" EXACT [GOC:TermGenie] +synonym: "upregulation of endogenous peptide antigen processing and presentation via MHC class I" EXACT [GOC:TermGenie] +is_a: GO:0002591 ! positive regulation of antigen processing and presentation of peptide antigen via MHC class I +is_a: GO:1904282 ! regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +relationship: positively_regulates GO:0019885 ! antigen processing and presentation of endogenous peptide antigen via MHC class I +created_by: rl +creation_date: 2015-06-04T12:05:49Z + +[Term] +id: GO:1904285 +name: regulation of protein-pyridoxal-5-phosphate linkage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +relationship: regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +created_by: mcc +creation_date: 2015-06-05T17:21:14Z + +[Term] +id: GO:1904286 +name: negative regulation of protein-pyridoxal-5-phosphate linkage +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] +synonym: "down regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +synonym: "downregulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +synonym: "inhibition of protein-pyridoxal-5-phosphate linkage" NARROW [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1904285 ! regulation of protein-pyridoxal-5-phosphate linkage +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +relationship: negatively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +created_by: mcc +creation_date: 2015-06-05T17:21:21Z + +[Term] +id: GO:1904287 +name: positive regulation of protein-pyridoxal-5-phosphate linkage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] +synonym: "activation of protein-pyridoxal-5-phosphate linkage" NARROW [GOC:TermGenie] +synonym: "stimulation of protein-pyridoxal-5-phosphate linkage" EXACT [] +synonym: "up regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +synonym: "upregulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1904285 ! regulation of protein-pyridoxal-5-phosphate linkage +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +relationship: positively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage +created_by: mcc +creation_date: 2015-06-05T17:21:28Z + +[Term] +id: GO:1904288 +name: BAT3 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a BAT3 complex." [GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23246001] +synonym: "Bag6 complex binding" EXACT [GOC:TermGenie] +synonym: "BAG6-UBL4A-TRC35 complex binding" EXACT [GOC:TermGenie] +synonym: "BAT3-TRC35-UBL4A complex binding" RELATED [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2015-06-07T19:48:55Z + +[Term] +id: GO:1904289 +name: regulation of mitotic DNA damage checkpoint +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16549501] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:2000001 ! regulation of DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044773 ! mitotic DNA damage checkpoint +relationship: regulates GO:0044773 ! mitotic DNA damage checkpoint +created_by: kmv +creation_date: 2015-06-09T13:03:11Z + +[Term] +id: GO:1904290 +name: negative regulation of mitotic DNA damage checkpoint +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16549501] +synonym: "down regulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic DNA damage checkpoint" NARROW [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:1904289 ! regulation of mitotic DNA damage checkpoint +is_a: GO:2000002 ! negative regulation of DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044773 ! mitotic DNA damage checkpoint +relationship: negatively_regulates GO:0044773 ! mitotic DNA damage checkpoint +created_by: kmv +creation_date: 2015-06-09T13:03:17Z + +[Term] +id: GO:1904291 +name: positive regulation of mitotic DNA damage checkpoint +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:16549501] +synonym: "activation of mitotic DNA damage checkpoint" NARROW [GOC:TermGenie] +synonym: "up regulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic DNA damage checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1904289 ! regulation of mitotic DNA damage checkpoint +is_a: GO:2000003 ! positive regulation of DNA damage checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044773 ! mitotic DNA damage checkpoint +relationship: positively_regulates GO:0044773 ! mitotic DNA damage checkpoint +created_by: kmv +creation_date: 2015-06-09T13:03:23Z + +[Term] +id: GO:1904292 +name: regulation of ERAD pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ERAD pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +is_a: GO:0061136 ! regulation of proteasomal protein catabolic process +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036503 ! ERAD pathway +relationship: regulates GO:0036503 ! ERAD pathway +created_by: bf +creation_date: 2015-06-09T14:44:27Z + +[Term] +id: GO:1904293 +name: negative regulation of ERAD pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22590560] +synonym: "down regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of ERAD pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of ERAD pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of ERAD pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum-associated degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of ERAD pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +is_a: GO:1901799 ! negative regulation of proteasomal protein catabolic process +is_a: GO:1903573 ! negative regulation of response to endoplasmic reticulum stress +is_a: GO:1904292 ! regulation of ERAD pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036503 ! ERAD pathway +relationship: negatively_regulates GO:0036503 ! ERAD pathway +created_by: bf +creation_date: 2015-06-09T14:44:33Z + +[Term] +id: GO:1904294 +name: positive regulation of ERAD pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ERAD pathway." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of endoplasmic reticulum-associated degradation" NARROW [GOC:TermGenie] +synonym: "activation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "activation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "activation of ERAD pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of ERAD pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of ERAD pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of ERAD pathway" EXACT [GOC:TermGenie] +is_a: GO:1901800 ! positive regulation of proteasomal protein catabolic process +is_a: GO:1904292 ! regulation of ERAD pathway +is_a: GO:1905898 ! positive regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036503 ! ERAD pathway +relationship: positively_regulates GO:0036503 ! ERAD pathway +created_by: bf +creation_date: 2015-06-09T14:44:39Z + +[Term] +id: GO:1904295 +name: regulation of osmolarity-sensing cation channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:18279313] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990760 ! osmolarity-sensing cation channel activity +relationship: regulates GO:1990760 ! osmolarity-sensing cation channel activity +created_by: sl +creation_date: 2015-06-09T17:35:40Z + +[Term] +id: GO:1904296 +name: negative regulation of osmolarity-sensing cation channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:18279313] +synonym: "down regulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +synonym: "inhibition of osmolarity-sensing cation channel activity" NARROW [GOC:TermGenie] +is_a: GO:1904295 ! regulation of osmolarity-sensing cation channel activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990760 ! osmolarity-sensing cation channel activity +relationship: negatively_regulates GO:1990760 ! osmolarity-sensing cation channel activity +created_by: sl +creation_date: 2015-06-09T17:35:46Z + +[Term] +id: GO:1904297 +name: positive regulation of osmolarity-sensing cation channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:18279313] +synonym: "activation of osmolarity-sensing cation channel activity" NARROW [GOC:TermGenie] +synonym: "up regulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of osmolarity-sensing cation channel activity" EXACT [GOC:TermGenie] +is_a: GO:1904295 ! regulation of osmolarity-sensing cation channel activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990760 ! osmolarity-sensing cation channel activity +relationship: positively_regulates GO:1990760 ! osmolarity-sensing cation channel activity +created_by: sl +creation_date: 2015-06-09T17:35:52Z + +[Term] +id: GO:1904298 +name: regulation of transcytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcytosis." [GO_REF:0000058, GOC:TermGenie, PMID:9664076] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045056 ! transcytosis +relationship: regulates GO:0045056 ! transcytosis +created_by: sl +creation_date: 2015-06-09T22:53:26Z + +[Term] +id: GO:1904299 +name: negative regulation of transcytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis." [GO_REF:0000058, GOC:TermGenie, PMID:9664076] +synonym: "down regulation of transcytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of transcytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of transcytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of transcytosis" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1904298 ! regulation of transcytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045056 ! transcytosis +relationship: negatively_regulates GO:0045056 ! transcytosis +created_by: sl +creation_date: 2015-06-09T22:53:32Z + +[Term] +id: GO:1904300 +name: positive regulation of transcytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcytosis." [GO_REF:0000058, GOC:TermGenie, PMID:9664076] +synonym: "activation of transcytosis" NARROW [GOC:TermGenie] +synonym: "up regulation of transcytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of transcytosis" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1904298 ! regulation of transcytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045056 ! transcytosis +relationship: positively_regulates GO:0045056 ! transcytosis +created_by: sl +creation_date: 2015-06-09T22:53:38Z + +[Term] +id: GO:1904301 +name: regulation of maternal process involved in parturition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060137 ! maternal process involved in parturition +relationship: regulates GO:0060137 ! maternal process involved in parturition +created_by: sl +creation_date: 2015-06-09T23:01:32Z + +[Term] +id: GO:1904302 +name: negative regulation of maternal process involved in parturition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751] +synonym: "down regulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +synonym: "down-regulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +synonym: "downregulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +synonym: "inhibition of maternal process involved in parturition" NARROW [GOC:TermGenie] +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904301 ! regulation of maternal process involved in parturition +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060137 ! maternal process involved in parturition +relationship: negatively_regulates GO:0060137 ! maternal process involved in parturition +created_by: sl +creation_date: 2015-06-09T23:01:38Z + +[Term] +id: GO:1904303 +name: positive regulation of maternal process involved in parturition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition." [GO_REF:0000058, GOC:TermGenie, PMID:1849751] +synonym: "activation of maternal process involved in parturition" NARROW [GOC:TermGenie] +synonym: "up regulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +synonym: "up-regulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +synonym: "upregulation of maternal process involved in parturition" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904301 ! regulation of maternal process involved in parturition +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060137 ! maternal process involved in parturition +relationship: positively_regulates GO:0060137 ! maternal process involved in parturition +created_by: sl +creation_date: 2015-06-09T23:01:45Z + +[Term] +id: GO:1904304 +name: regulation of gastro-intestinal system smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] +is_a: GO:0006940 ! regulation of smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +relationship: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +created_by: sl +creation_date: 2015-06-09T23:18:42Z + +[Term] +id: GO:1904305 +name: negative regulation of gastro-intestinal system smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] +synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +relationship: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +created_by: sl +creation_date: 2015-06-09T23:18:48Z + +[Term] +id: GO:1904306 +name: positive regulation of gastro-intestinal system smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] +synonym: "activation of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] +synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] +is_a: GO:0045987 ! positive regulation of smooth muscle contraction +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +relationship: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction +created_by: sl +creation_date: 2015-06-09T23:18:54Z + +[Term] +id: GO:1904307 +name: response to desipramine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20549303] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0036276 ! response to antidepressant +created_by: sl +creation_date: 2015-06-10T17:00:31Z + +[Term] +id: GO:1904308 +name: cellular response to desipramine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20549303] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1904307 ! response to desipramine +created_by: sl +creation_date: 2015-06-10T17:00:37Z + +[Term] +id: GO:1904309 +name: response to cordycepin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21597460] +synonym: "response to 3'-deoxyadenosine" EXACT [GOC:sl] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097329 ! response to antimetabolite +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-06-10T17:10:29Z + +[Term] +id: GO:1904310 +name: cellular response to cordycepin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21597460] +synonym: "cellular response to 3'-deoxyadenosine" EXACT [GOC:sl] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904309 ! response to cordycepin +created_by: sl +creation_date: 2015-06-10T17:10:35Z + +[Term] +id: GO:1904311 +name: response to gold(3+) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16206274] +is_a: GO:0010035 ! response to inorganic substance +created_by: sl +creation_date: 2015-06-10T17:41:07Z + +[Term] +id: GO:1904312 +name: cellular response to gold(3+) +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16206274] +is_a: GO:0070887 ! cellular response to chemical stimulus +is_a: GO:1904311 ! response to gold(3+) +created_by: sl +creation_date: 2015-06-10T17:41:13Z + +[Term] +id: GO:1904313 +name: response to methamphetamine hydrochloride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22174933] +synonym: "response to methamphetamine HCL" EXACT [] +is_a: GO:1902074 ! response to salt +created_by: sl +creation_date: 2015-06-10T17:47:09Z + +[Term] +id: GO:1904314 +name: cellular response to methamphetamine hydrochloride +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22174933] +synonym: "cellular response to methamphetamine HCL" EXACT [] +is_a: GO:1902075 ! cellular response to salt +is_a: GO:1904313 ! response to methamphetamine hydrochloride +created_by: sl +creation_date: 2015-06-10T17:47:15Z + +[Term] +id: GO:1904315 +name: transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential." [GO_REF:0000061, GOC:TermGenie, PMID:20200227] +subset: goslim_synapse +synonym: "ionotropic neurotransmitter receptor activity involved in regulation of post-synaptic membrane potential" NARROW [GOC:TermGenie] +synonym: "ionotropic neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential" NARROW [GOC:TermGenie] +is_a: GO:0022824 ! transmitter-gated ion channel activity +is_a: GO:0099529 ! neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential +intersection_of: GO:0022824 ! transmitter-gated ion channel activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +created_by: dos +creation_date: 2015-06-10T18:02:07Z + +[Term] +id: GO:1904316 +name: response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:9321918] +synonym: "response to PAF" EXACT [] +synonym: "response to platelet-activating factor" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0042493 ! response to drug +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-06-10T18:10:17Z + +[Term] +id: GO:1904317 +name: cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:9321918] +synonym: "cellular response to PAF" EXACT [] +synonym: "cellular response to platelet-activating factor" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904316 ! response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine +created_by: sl +creation_date: 2015-06-10T18:10:23Z + +[Term] +id: GO:1904318 +name: regulation of smooth muscle contraction involved in micturition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] +synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +is_a: GO:0006940 ! regulation of smooth muscle contraction +is_a: GO:0044062 ! regulation of excretion +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060083 ! smooth muscle contraction involved in micturition +relationship: regulates GO:0060083 ! smooth muscle contraction involved in micturition +created_by: sl +creation_date: 2015-06-10T18:46:11Z + +[Term] +id: GO:1904319 +name: negative regulation of smooth muscle contraction involved in micturition +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] +synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "down-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "down-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "downregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "downregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "inhibition of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] +synonym: "inhibition of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition +relationship: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition +created_by: sl +creation_date: 2015-06-10T18:46:17Z + +[Term] +id: GO:1904320 +name: positive regulation of smooth muscle contraction involved in micturition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] +synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] +synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "positive regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "positive regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "up regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "up regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "up-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] +synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] +is_a: GO:0045987 ! positive regulation of smooth muscle contraction +is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition +relationship: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition +created_by: sl +creation_date: 2015-06-10T18:46:23Z + +[Term] +id: GO:1904321 +name: response to forskolin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:15937517] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0061478 ! response to platelet aggregation inhibitor +is_a: GO:0097305 ! response to alcohol +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-06-10T19:01:27Z + +[Term] +id: GO:1904322 +name: cellular response to forskolin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:15937517] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904321 ! response to forskolin +created_by: sl +creation_date: 2015-06-10T19:01:33Z + +[Term] +id: GO:1904323 +name: regulation of inhibitory G protein-coupled receptor phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] +synonym: "regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] +is_a: GO:0001932 ! regulation of protein phosphorylation +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +relationship: regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +created_by: sl +creation_date: 2015-06-10T19:46:37Z + +[Term] +id: GO:1904324 +name: negative regulation of inhibitory G protein-coupled receptor phosphorylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] +synonym: "down regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +synonym: "inhibition of inhibitory G-protein coupled receptor phosphorylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] +is_a: GO:0001933 ! negative regulation of protein phosphorylation +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:1904323 ! regulation of inhibitory G protein-coupled receptor phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +relationship: negatively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +created_by: sl +creation_date: 2015-06-10T19:46:43Z + +[Term] +id: GO:1904325 +name: positive regulation of inhibitory G protein-coupled receptor phosphorylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] +synonym: "activation of inhibitory G-protein coupled receptor phosphorylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] +synonym: "up regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] +is_a: GO:0001934 ! positive regulation of protein phosphorylation +is_a: GO:1904323 ! regulation of inhibitory G protein-coupled receptor phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +relationship: positively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation +created_by: sl +creation_date: 2015-06-10T19:46:50Z + +[Term] +id: GO:1904326 +name: negative regulation of circadian sleep/wake cycle, wakefulness +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness." [GO_REF:0000058, GOC:TermGenie, PMID:10923657] +synonym: "down regulation of circadian sleep/wake cycle, wakefulness" EXACT [GOC:TermGenie] +synonym: "down-regulation of circadian sleep/wake cycle, wakefulness" EXACT [GOC:TermGenie] +synonym: "downregulation of circadian sleep/wake cycle, wakefulness" EXACT [GOC:TermGenie] +synonym: "inhibition of circadian sleep/wake cycle, wakefulness" NARROW [GOC:TermGenie] +is_a: GO:0010840 ! regulation of circadian sleep/wake cycle, wakefulness +is_a: GO:0042754 ! negative regulation of circadian rhythm +is_a: GO:0048521 ! negative regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness +relationship: negatively_regulates GO:0042746 ! circadian sleep/wake cycle, wakefulness +created_by: sl +creation_date: 2015-06-10T20:18:45Z + +[Term] +id: GO:1904327 +name: protein localization to cytosolic proteasome complex +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex." [GO_REF:0000087, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17000876] +synonym: "protein localisation in cytosolic proteasome complex" EXACT [GOC:TermGenie] +synonym: "protein localisation to cytosolic proteasome complex" EXACT [GOC:TermGenie] +synonym: "protein localization in cytosolic proteasome complex" EXACT [GOC:TermGenie] +is_a: GO:0008104 ! protein localization +created_by: bf +creation_date: 2015-06-11T09:29:53Z + +[Term] +id: GO:1904328 +name: regulation of myofibroblast contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myofibroblast contraction." [GO_REF:0000058, GOC:TermGenie, PMID:19239477] +synonym: "regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "regulation of MFB contraction" EXACT [GOC:TermGenie] +is_a: GO:1903115 ! regulation of actin filament-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990764 ! myofibroblast contraction +relationship: regulates GO:1990764 ! myofibroblast contraction +created_by: sl +creation_date: 2015-06-11T15:30:29Z + +[Term] +id: GO:1904329 +name: negative regulation of myofibroblast contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction." [GO_REF:0000058, GOC:TermGenie, PMID:19239477] +synonym: "down regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "down regulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "down regulation of myofibroblast contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of myofibroblast contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of myofibroblast contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of MF contraction" NARROW [GOC:TermGenie] +synonym: "inhibition of MFB contraction" NARROW [GOC:TermGenie] +synonym: "inhibition of myofibroblast contraction" NARROW [GOC:TermGenie] +synonym: "negative regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "negative regulation of MFB contraction" EXACT [GOC:TermGenie] +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:1904328 ! regulation of myofibroblast contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990764 ! myofibroblast contraction +relationship: negatively_regulates GO:1990764 ! myofibroblast contraction +created_by: sl +creation_date: 2015-06-11T15:30:35Z + +[Term] +id: GO:1904330 +name: positive regulation of myofibroblast contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myofibroblast contraction." [GO_REF:0000058, GOC:TermGenie, PMID:19239477] +synonym: "activation of MF contraction" NARROW [GOC:TermGenie] +synonym: "activation of MFB contraction" NARROW [GOC:TermGenie] +synonym: "activation of myofibroblast contraction" NARROW [GOC:TermGenie] +synonym: "positive regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "positive regulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "up regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "up regulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "up regulation of myofibroblast contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of myofibroblast contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of MF contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of MFB contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of myofibroblast contraction" EXACT [GOC:TermGenie] +is_a: GO:1903116 ! positive regulation of actin filament-based movement +is_a: GO:1904328 ! regulation of myofibroblast contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990764 ! myofibroblast contraction +relationship: positively_regulates GO:1990764 ! myofibroblast contraction +created_by: sl +creation_date: 2015-06-11T15:30:41Z + +[Term] +id: GO:1904331 +name: regulation of error-prone translesion synthesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of error-prone translesion synthesis." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22761594] +synonym: "regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "regulation of mutagenic PRR" EXACT [GOC:TermGenie] +is_a: GO:0006282 ! regulation of DNA repair +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042276 ! error-prone translesion synthesis +relationship: regulates GO:0042276 ! error-prone translesion synthesis +created_by: kmv +creation_date: 2015-06-11T16:24:47Z + +[Term] +id: GO:1904332 +name: negative regulation of error-prone translesion synthesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22761594] +synonym: "down regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "down regulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "down regulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "down-regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "down-regulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "down-regulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "downregulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "downregulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "downregulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "inhibition of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "inhibition of error-prone translesion synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "inhibition of mutagenic PRR" NARROW [GOC:TermGenie] +synonym: "negative regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "negative regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "negative regulation of mutagenic PRR" EXACT [GOC:TermGenie] +is_a: GO:0045738 ! negative regulation of DNA repair +is_a: GO:1904331 ! regulation of error-prone translesion synthesis +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042276 ! error-prone translesion synthesis +relationship: negatively_regulates GO:0042276 ! error-prone translesion synthesis +created_by: kmv +creation_date: 2015-06-11T16:24:53Z + +[Term] +id: GO:1904333 +name: positive regulation of error-prone translesion synthesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:22761594] +synonym: "activation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "activation of error-prone translesion synthesis" NARROW [GOC:TermGenie] +synonym: "activation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "activation of mutagenic PRR" NARROW [GOC:TermGenie] +synonym: "positive regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "positive regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "positive regulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "up regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "up regulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "up regulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "up-regulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "up-regulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "up-regulation of mutagenic PRR" EXACT [GOC:TermGenie] +synonym: "upregulation of error-prone postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "upregulation of error-prone translesion synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of mutagenic postreplication DNA repair" RELATED [GOC:TermGenie] +synonym: "upregulation of mutagenic PRR" EXACT [GOC:TermGenie] +is_a: GO:0045739 ! positive regulation of DNA repair +is_a: GO:1904331 ! regulation of error-prone translesion synthesis +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042276 ! error-prone translesion synthesis +relationship: positively_regulates GO:0042276 ! error-prone translesion synthesis +created_by: kmv +creation_date: 2015-06-11T16:25:10Z + +[Term] +id: GO:1904334 +name: heme import across plasma membrane +namespace: biological_process +def: "The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:25733668] +synonym: "heme assimilation" BROAD [] +is_a: GO:0035351 ! heme transmembrane transport +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:0140420 ! heme import into cell +created_by: al +creation_date: 2015-06-11T16:56:21Z + +[Term] +id: GO:1904335 +name: regulation of ductus arteriosus closure +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ductus arteriosus closure." [GO_REF:0000058, GOC:TermGenie, PMID:16303610] +is_a: GO:1905651 ! regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097070 ! ductus arteriosus closure +relationship: regulates GO:0097070 ! ductus arteriosus closure +created_by: sl +creation_date: 2015-06-11T17:45:15Z + +[Term] +id: GO:1904336 +name: negative regulation of ductus arteriosus closure +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure." [GO_REF:0000058, GOC:TermGenie, PMID:16303610] +synonym: "down regulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +synonym: "down-regulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +synonym: "downregulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +synonym: "inhibition of ductus arteriosus closure" NARROW [GOC:TermGenie] +is_a: GO:1904335 ! regulation of ductus arteriosus closure +is_a: GO:1905652 ! negative regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097070 ! ductus arteriosus closure +relationship: negatively_regulates GO:0097070 ! ductus arteriosus closure +created_by: sl +creation_date: 2015-06-11T17:45:21Z + +[Term] +id: GO:1904337 +name: positive regulation of ductus arteriosus closure +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure." [GO_REF:0000058, GOC:TermGenie, PMID:16303610] +synonym: "activation of ductus arteriosus closure" NARROW [GOC:TermGenie] +synonym: "up regulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +synonym: "up-regulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +synonym: "upregulation of ductus arteriosus closure" EXACT [GOC:TermGenie] +is_a: GO:1904335 ! regulation of ductus arteriosus closure +is_a: GO:1905653 ! positive regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097070 ! ductus arteriosus closure +relationship: positively_regulates GO:0097070 ! ductus arteriosus closure +created_by: sl +creation_date: 2015-06-11T17:45:27Z + +[Term] +id: GO:1904338 +name: regulation of dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:15522889] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071542 ! dopaminergic neuron differentiation +relationship: regulates GO:0071542 ! dopaminergic neuron differentiation +created_by: sl +creation_date: 2015-06-11T18:06:19Z + +[Term] +id: GO:1904339 +name: negative regulation of dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:15522889] +synonym: "down regulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:1904338 ! regulation of dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071542 ! dopaminergic neuron differentiation +relationship: negatively_regulates GO:0071542 ! dopaminergic neuron differentiation +created_by: sl +creation_date: 2015-06-11T18:06:25Z + +[Term] +id: GO:1904340 +name: positive regulation of dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:15522889] +synonym: "activation of dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:1904338 ! regulation of dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071542 ! dopaminergic neuron differentiation +relationship: positively_regulates GO:0071542 ! dopaminergic neuron differentiation +created_by: sl +creation_date: 2015-06-11T18:06:32Z + +[Term] +id: GO:1904341 +name: regulation of colon smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990765 ! colon smooth muscle contraction +relationship: regulates GO:1990765 ! colon smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:16:58Z + +[Term] +id: GO:1904342 +name: negative regulation of colon smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] +synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of colon smooth muscle contraction" NARROW [GOC:TermGenie] +is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction +is_a: GO:1904341 ! regulation of colon smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990765 ! colon smooth muscle contraction +relationship: negatively_regulates GO:1990765 ! colon smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:17:05Z + +[Term] +id: GO:1904343 +name: positive regulation of colon smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] +synonym: "activation of colon smooth muscle contraction" NARROW [GOC:TermGenie] +synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] +is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction +is_a: GO:1904341 ! regulation of colon smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990765 ! colon smooth muscle contraction +relationship: positively_regulates GO:1990765 ! colon smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:17:11Z + +[Term] +id: GO:1904344 +name: regulation of gastric mucosal blood circulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] +synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +is_a: GO:1903522 ! regulation of blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990768 ! gastric mucosal blood circulation +relationship: regulates GO:1990768 ! gastric mucosal blood circulation +created_by: sl +creation_date: 2015-06-11T21:20:31Z + +[Term] +id: GO:1904345 +name: negative regulation of gastric mucosal blood circulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] +synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "inhibition of gastric mucosal blood circulation" NARROW [GOC:TermGenie] +synonym: "inhibition of stomach mucosal blood circulation" NARROW [GOC:TermGenie] +synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +is_a: GO:1903523 ! negative regulation of blood circulation +is_a: GO:1904344 ! regulation of gastric mucosal blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990768 ! gastric mucosal blood circulation +relationship: negatively_regulates GO:1990768 ! gastric mucosal blood circulation +created_by: sl +creation_date: 2015-06-11T21:20:44Z + +[Term] +id: GO:1904346 +name: positive regulation of gastric mucosal blood circulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] +synonym: "activation of gastric mucosal blood circulation" NARROW [GOC:TermGenie] +synonym: "activation of stomach mucosal blood circulation" NARROW [GOC:TermGenie] +synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] +synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] +is_a: GO:1903524 ! positive regulation of blood circulation +is_a: GO:1904344 ! regulation of gastric mucosal blood circulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990768 ! gastric mucosal blood circulation +relationship: positively_regulates GO:1990768 ! gastric mucosal blood circulation +created_by: sl +creation_date: 2015-06-11T21:20:50Z + +[Term] +id: GO:1904347 +name: regulation of small intestine smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] +is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990770 ! small intestine smooth muscle contraction +relationship: regulates GO:1990770 ! small intestine smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:37:34Z + +[Term] +id: GO:1904348 +name: negative regulation of small intestine smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] +synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] +is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction +is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction +relationship: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:37:40Z + +[Term] +id: GO:1904349 +name: positive regulation of small intestine smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] +synonym: "activation of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] +synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] +is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction +is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990770 ! small intestine smooth muscle contraction +relationship: positively_regulates GO:1990770 ! small intestine smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T21:37:46Z + +[Term] +id: GO:1904350 +name: regulation of protein catabolic process in the vacuole +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] +synonym: "regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +is_a: GO:1903362 ! regulation of cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007039 ! protein catabolic process in the vacuole +relationship: regulates GO:0007039 ! protein catabolic process in the vacuole +created_by: rl +creation_date: 2015-06-12T09:10:36Z + +[Term] +id: GO:1904351 +name: negative regulation of protein catabolic process in the vacuole +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] +synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "down regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "down regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "down regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "down-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "down-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "down-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "down-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "downregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "downregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "downregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "downregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "inhibition of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] +synonym: "inhibition of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "inhibition of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "inhibition of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "inhibition of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "negative regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "negative regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "negative regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "negative regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +is_a: GO:1903363 ! negative regulation of cellular protein catabolic process +is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole +relationship: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole +created_by: rl +creation_date: 2015-06-12T09:10:42Z + +[Term] +id: GO:1904352 +name: positive regulation of protein catabolic process in the vacuole +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] +synonym: "activation of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] +synonym: "activation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "activation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "activation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "activation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "positive regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "positive regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "positive regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "positive regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "up regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "up regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "up regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "up-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "up-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "up-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "up-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] +synonym: "upregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] +synonym: "upregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] +synonym: "upregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] +synonym: "upregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] +is_a: GO:1903364 ! positive regulation of cellular protein catabolic process +is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007039 ! protein catabolic process in the vacuole +relationship: positively_regulates GO:0007039 ! protein catabolic process in the vacuole +created_by: rl +creation_date: 2015-06-12T09:10:49Z + +[Term] +id: GO:1904353 +name: regulation of telomere capping +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomere capping." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +synonym: "regulation of telomere end protection" EXACT [GOC:TermGenie] +is_a: GO:0032204 ! regulation of telomere maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016233 ! telomere capping +relationship: regulates GO:0016233 ! telomere capping +created_by: nc +creation_date: 2015-06-12T16:51:08Z + +[Term] +id: GO:1904354 +name: negative regulation of telomere capping +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +synonym: "down regulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "down regulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "inhibition of telomere capping" NARROW [GOC:TermGenie] +synonym: "inhibition of telomere end protection" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomere end protection" EXACT [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904353 ! regulation of telomere capping +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016233 ! telomere capping +relationship: negatively_regulates GO:0016233 ! telomere capping +created_by: nc +creation_date: 2015-06-12T16:51:14Z + +[Term] +id: GO:1904355 +name: positive regulation of telomere capping +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomere capping." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +synonym: "activation of telomere capping" NARROW [GOC:TermGenie] +synonym: "activation of telomere end protection" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "up regulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "up regulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomere end protection" EXACT [GOC:TermGenie] +synonym: "upregulation of telomere capping" EXACT [GOC:TermGenie] +synonym: "upregulation of telomere end protection" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:1904353 ! regulation of telomere capping +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016233 ! telomere capping +relationship: positively_regulates GO:0016233 ! telomere capping +created_by: nc +creation_date: 2015-06-12T16:51:20Z + +[Term] +id: GO:1904356 +name: regulation of telomere maintenance via telomere lengthening +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +is_a: GO:0032204 ! regulation of telomere maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010833 ! telomere maintenance via telomere lengthening +relationship: regulates GO:0010833 ! telomere maintenance via telomere lengthening +created_by: nc +creation_date: 2015-06-12T16:53:16Z + +[Term] +id: GO:1904357 +name: negative regulation of telomere maintenance via telomere lengthening +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +synonym: "down regulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +synonym: "inhibition of telomere maintenance via telomere lengthening" NARROW [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904356 ! regulation of telomere maintenance via telomere lengthening +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010833 ! telomere maintenance via telomere lengthening +relationship: negatively_regulates GO:0010833 ! telomere maintenance via telomere lengthening +created_by: nc +creation_date: 2015-06-12T16:53:22Z + +[Term] +id: GO:1904358 +name: positive regulation of telomere maintenance via telomere lengthening +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] +synonym: "activation of telomere maintenance via telomere lengthening" NARROW [GOC:TermGenie] +synonym: "up regulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +synonym: "upregulation of telomere maintenance via telomere lengthening" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:1904356 ! regulation of telomere maintenance via telomere lengthening +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010833 ! telomere maintenance via telomere lengthening +relationship: positively_regulates GO:0010833 ! telomere maintenance via telomere lengthening +created_by: nc +creation_date: 2015-06-12T16:53:28Z + +[Term] +id: GO:1904359 +name: regulation of spore germination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of spore germination." [GO_REF:0000058, GOC:TermGenie, PMID:14718564, PMID:8798577] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009847 ! spore germination +relationship: regulates GO:0009847 ! spore germination +created_by: pf +creation_date: 2015-06-12T19:46:06Z + +[Term] +id: GO:1904360 +name: negative regulation of spore germination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of spore germination." [GO_REF:0000058, GOC:TermGenie, PMID:14718564, PMID:8798577] +synonym: "down regulation of spore germination" EXACT [GOC:TermGenie] +synonym: "down-regulation of spore germination" EXACT [GOC:TermGenie] +synonym: "downregulation of spore germination" EXACT [GOC:TermGenie] +synonym: "inhibition of spore germination" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1904359 ! regulation of spore germination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009847 ! spore germination +relationship: negatively_regulates GO:0009847 ! spore germination +created_by: pf +creation_date: 2015-06-12T19:46:12Z + +[Term] +id: GO:1904361 +name: positive regulation of spore germination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spore germination." [GO_REF:0000058, GOC:TermGenie, PMID:14718564, PMID:8798577] +synonym: "activation of spore germination" NARROW [GOC:TermGenie] +synonym: "up regulation of spore germination" EXACT [GOC:TermGenie] +synonym: "up-regulation of spore germination" EXACT [GOC:TermGenie] +synonym: "upregulation of spore germination" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1904359 ! regulation of spore germination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009847 ! spore germination +relationship: positively_regulates GO:0009847 ! spore germination +created_by: pf +creation_date: 2015-06-12T19:46:18Z + +[Term] +id: GO:1904362 +name: regulation of calcitonin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcitonin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +is_a: GO:0090276 ! regulation of peptide hormone secretion +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036161 ! calcitonin secretion +relationship: regulates GO:0036161 ! calcitonin secretion +created_by: sl +creation_date: 2015-06-15T17:54:52Z + +[Term] +id: GO:1904363 +name: negative regulation of calcitonin secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +synonym: "down regulation of calcitonin secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcitonin secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of calcitonin secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of calcitonin secretion" NARROW [GOC:TermGenie] +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +is_a: GO:1904362 ! regulation of calcitonin secretion +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036161 ! calcitonin secretion +relationship: negatively_regulates GO:0036161 ! calcitonin secretion +created_by: sl +creation_date: 2015-06-15T17:54:58Z + +[Term] +id: GO:1904364 +name: positive regulation of calcitonin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcitonin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +synonym: "activation of calcitonin secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of calcitonin secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcitonin secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of calcitonin secretion" EXACT [GOC:TermGenie] +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +is_a: GO:1904362 ! regulation of calcitonin secretion +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036161 ! calcitonin secretion +relationship: positively_regulates GO:0036161 ! calcitonin secretion +created_by: sl +creation_date: 2015-06-15T17:55:05Z + +[Term] +id: GO:1904365 +name: regulation of chemokinesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokinesis." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042466 ! chemokinesis +relationship: regulates GO:0042466 ! chemokinesis +created_by: sl +creation_date: 2015-06-15T22:44:06Z + +[Term] +id: GO:1904366 +name: negative regulation of chemokinesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +synonym: "down regulation of chemokinesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemokinesis" EXACT [GOC:TermGenie] +synonym: "downregulation of chemokinesis" EXACT [GOC:TermGenie] +synonym: "inhibition of chemokinesis" NARROW [GOC:TermGenie] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:1904365 ! regulation of chemokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042466 ! chemokinesis +relationship: negatively_regulates GO:0042466 ! chemokinesis +created_by: sl +creation_date: 2015-06-15T22:44:12Z + +[Term] +id: GO:1904367 +name: positive regulation of chemokinesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemokinesis." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +synonym: "activation of chemokinesis" NARROW [GOC:TermGenie] +synonym: "up regulation of chemokinesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemokinesis" EXACT [GOC:TermGenie] +synonym: "upregulation of chemokinesis" EXACT [GOC:TermGenie] +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:1904365 ! regulation of chemokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042466 ! chemokinesis +relationship: positively_regulates GO:0042466 ! chemokinesis +created_by: sl +creation_date: 2015-06-15T22:44:18Z + +[Term] +id: GO:1904368 +name: regulation of sclerenchyma cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:26025534] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014001 ! sclerenchyma cell differentiation +relationship: regulates GO:0014001 ! sclerenchyma cell differentiation +created_by: tb +creation_date: 2015-06-17T19:53:00Z + +[Term] +id: GO:1904369 +name: positive regulation of sclerenchyma cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:26025534] +synonym: "up regulation of sclerenchyma cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of sclerenchyma cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of sclerenchyma cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1904368 ! regulation of sclerenchyma cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014001 ! sclerenchyma cell differentiation +relationship: positively_regulates GO:0014001 ! sclerenchyma cell differentiation +created_by: tb +creation_date: 2015-06-17T19:53:06Z + +[Term] +id: GO:1904370 +name: regulation of protein localization to actin cortical patch +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +synonym: "regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +is_a: GO:1904776 ! regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044379 ! protein localization to actin cortical patch +relationship: regulates GO:0044379 ! protein localization to actin cortical patch +created_by: sl +creation_date: 2015-06-18T22:23:31Z + +[Term] +id: GO:1904371 +name: negative regulation of protein localization to actin cortical patch +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +synonym: "down regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to actin cortical patch" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to actin cortical patch" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +is_a: GO:1904370 ! regulation of protein localization to actin cortical patch +is_a: GO:1904777 ! negative regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044379 ! protein localization to actin cortical patch +relationship: negatively_regulates GO:0044379 ! protein localization to actin cortical patch +created_by: sl +creation_date: 2015-06-18T22:23:37Z + +[Term] +id: GO:1904372 +name: positive regulation of protein localization to actin cortical patch +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +synonym: "activation of protein localisation to actin cortical patch" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to actin cortical patch" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to actin cortical patch" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to actin cortical patch" EXACT [GOC:TermGenie] +is_a: GO:1904370 ! regulation of protein localization to actin cortical patch +is_a: GO:1904778 ! positive regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044379 ! protein localization to actin cortical patch +relationship: positively_regulates GO:0044379 ! protein localization to actin cortical patch +created_by: sl +creation_date: 2015-06-18T22:23:43Z + +[Term] +id: GO:1904373 +name: response to kainic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17443789] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +created_by: sl +creation_date: 2015-06-18T22:42:52Z + +[Term] +id: GO:1904374 +name: cellular response to kainic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17443789] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1904373 ! response to kainic acid +created_by: sl +creation_date: 2015-06-18T22:42:58Z + +[Term] +id: GO:1904375 +name: regulation of protein localization to cell periphery +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990778 ! protein localization to cell periphery +relationship: regulates GO:1990778 ! protein localization to cell periphery +created_by: sl +creation_date: 2015-06-22T22:09:25Z + +[Term] +id: GO:1904376 +name: negative regulation of protein localization to cell periphery +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localization to cell periphery" NARROW [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1904375 ! regulation of protein localization to cell periphery +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990778 ! protein localization to cell periphery +relationship: negatively_regulates GO:1990778 ! protein localization to cell periphery +created_by: sl +creation_date: 2015-06-22T22:09:32Z + +[Term] +id: GO:1904377 +name: positive regulation of protein localization to cell periphery +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] +synonym: "activation of protein localization to cell periphery" NARROW [GOC:TermGenie] +synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1904375 ! regulation of protein localization to cell periphery +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990778 ! protein localization to cell periphery +relationship: positively_regulates GO:1990778 ! protein localization to cell periphery +created_by: sl +creation_date: 2015-06-22T22:09:37Z + +[Term] +id: GO:1904378 +name: maintenance of unfolded protein involved in ERAD pathway +namespace: biological_process +def: "Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome." [GO_REF:0000060, GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, GOC:TermGenie, PMID:21636303] +synonym: "chaperone holdase activity" RELATED [PMID:23417671] +synonym: "ERAD chaperone-like activity" RELATED [GOC:bf] +synonym: "holdase activity" RELATED [PMID:21636303] +synonym: "maintenance of unfolded protein during ERAD" RELATED [GOC:bf] +synonym: "maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "maintenance of unfolded protein involved in ER-associated degradation pathway" RELATED [GOC:TermGenie] +is_a: GO:0036506 ! maintenance of unfolded protein +intersection_of: GO:0036506 ! maintenance of unfolded protein +intersection_of: part_of GO:0036503 ! ERAD pathway +relationship: part_of GO:0036503 ! ERAD pathway +created_by: bf +creation_date: 2015-06-23T09:21:53Z + +[Term] +id: GO:1904379 +name: protein localization to cytosolic proteasome complex involved in ERAD pathway +namespace: biological_process +def: "Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation." [GO_REF:0000060, GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, GOC:TermGenie, PMID:21636303] +synonym: "protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localisation in cytosolic proteasome complex involved in ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localisation in cytosolic proteasome complex involved in ERAD pathway" EXACT [GOC:TermGenie] +synonym: "protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localisation to cytosolic proteasome complex involved in ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localisation to cytosolic proteasome complex involved in ERAD pathway" EXACT [GOC:TermGenie] +synonym: "protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localization in cytosolic proteasome complex involved in ER-associated degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localization in cytosolic proteasome complex involved in ERAD pathway" EXACT [GOC:TermGenie] +synonym: "protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation" EXACT [GOC:TermGenie] +synonym: "protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway" RELATED [GOC:TermGenie] +synonym: "protein localization to cytosolic proteasome complex involved in ER-associated degradation pathway" RELATED [GOC:TermGenie] +is_a: GO:1904327 ! protein localization to cytosolic proteasome complex +intersection_of: GO:1904327 ! protein localization to cytosolic proteasome complex +intersection_of: part_of GO:0036503 ! ERAD pathway +relationship: part_of GO:0036503 ! ERAD pathway +created_by: bf +creation_date: 2015-06-23T09:30:07Z + +[Term] +id: GO:1904380 +name: endoplasmic reticulum mannose trimming +namespace: biological_process +def: "Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC)." [GO_REF:0000062, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24519966] +synonym: "ER mannose trimming" EXACT [GOC:bf] +synonym: "ER protein alpha-1,2-demannosylation" EXACT [GOC:bf] +synonym: "glycoprotein mannose trimming in endoplasmic reticulum quality control compartment" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming in ER quality control compartment" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming in ER-derived quality control compartment" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming in ERQC" RELATED [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation in endoplasmic reticulum" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation in endoplasmic reticulum quality control compartment" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation in ER" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation in ER quality control compartment" EXACT [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation in ER-derived quality control compartment" RELATED [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation in ERQC" EXACT [GOC:TermGenie] +is_a: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: occurs_in GO:0044322 ! endoplasmic reticulum quality control compartment +relationship: occurs_in GO:0044322 ! endoplasmic reticulum quality control compartment +created_by: bf +creation_date: 2015-06-23T09:35:41Z + +[Term] +id: GO:1904381 +name: Golgi apparatus mannose trimming +namespace: biological_process +def: "Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus." [GO_REF:0000062, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:10915796] +synonym: "glycoprotein mannose trimming in Golgi apparatus" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming in Golgi complex" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming in Golgi ribbon" RELATED [GOC:TermGenie] +synonym: "mannose trimming in cis-Golgi" NARROW [GOC:bf] +synonym: "mannose trimming in Golgi" BROAD [GOC:TermGenie] +synonym: "mannose trimming in Golgi apparatus" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation in Golgi apparatus" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation in Golgi complex" EXACT [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation in Golgi ribbon" NARROW [GOC:TermGenie] +is_a: GO:0006491 ! N-glycan processing +is_a: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: occurs_in GO:0005794 ! Golgi apparatus +relationship: occurs_in GO:0005794 ! Golgi apparatus +created_by: bf +creation_date: 2015-06-23T09:42:06Z + +[Term] +id: GO:1904382 +name: mannose trimming involved in glycoprotein ERAD pathway +namespace: biological_process +def: "The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD)." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24519966] +synonym: "glycoprotein mannose trimming involved in ER-associated glycoprotein degradation" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming involved in glycoprotein ERAD" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming involved in glycoprotein ERAD pathway" RELATED [GOC:TermGenie] +synonym: "glycoprotein mannose trimming involved in gpERAD" RELATED [GOC:TermGenie] +synonym: "mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process" BROAD [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation" EXACT [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation involved in glycoprotein ERAD" EXACT [GOC:TermGenie] +synonym: "protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway" EXACT [GOC:bf] +synonym: "protein alpha-1,2-demannosylation involved in gpERAD" EXACT [GOC:TermGenie] +is_a: GO:0035977 ! protein deglycosylation involved in glycoprotein catabolic process +is_a: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: GO:0036508 ! protein alpha-1,2-demannosylation +intersection_of: part_of GO:0097466 ! ubiquitin-dependent glycoprotein ERAD pathway +relationship: part_of GO:0097466 ! ubiquitin-dependent glycoprotein ERAD pathway +created_by: bf +creation_date: 2015-06-23T09:46:55Z + +[Term] +id: GO:1904383 +name: response to sodium phosphate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24625659] +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:1902074 ! response to salt +created_by: sl +creation_date: 2015-06-23T16:55:07Z + +[Term] +id: GO:1904384 +name: cellular response to sodium phosphate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24625659] +is_a: GO:1902075 ! cellular response to salt +is_a: GO:1904383 ! response to sodium phosphate +created_by: sl +creation_date: 2015-06-23T16:55:13Z + +[Term] +id: GO:1904385 +name: cellular response to angiotensin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen." [GO_REF:0000071, GOC:TermGenie, PMID:22982863] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1990776 ! response to angiotensin +created_by: sl +creation_date: 2015-06-23T17:27:14Z + +[Term] +id: GO:1904386 +name: response to L-phenylalanine derivative +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12112407] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: sl +creation_date: 2015-06-23T17:56:19Z + +[Term] +id: GO:1904387 +name: cellular response to L-phenylalanine derivative +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12112407] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1904386 ! response to L-phenylalanine derivative +created_by: sl +creation_date: 2015-06-23T17:56:25Z + +[Term] +id: GO:1904388 +name: negative regulation of ncRNA transcription associated with protein coding gene TSS/TES +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES." [GO_REF:0000058, GOC:TermGenie, PMID:20502517] +synonym: "down regulation of ncRNA transcription associated with protein coding gene TSS/TES" EXACT [GOC:TermGenie] +synonym: "down regulation of pasRNA transcription" NARROW [GOC:TermGenie] +synonym: "down-regulation of ncRNA transcription associated with protein coding gene TSS/TES" EXACT [GOC:TermGenie] +synonym: "down-regulation of pasRNA transcription" NARROW [GOC:TermGenie] +synonym: "downregulation of ncRNA transcription associated with protein coding gene TSS/TES" EXACT [GOC:TermGenie] +synonym: "downregulation of pasRNA transcription" NARROW [GOC:TermGenie] +synonym: "inhibition of ncRNA transcription associated with protein coding gene TSS/TES" NARROW [GOC:TermGenie] +synonym: "inhibition of pasRNA transcription" NARROW [GOC:TermGenie] +synonym: "negative regulation of pasRNA transcription" NARROW [GOC:TermGenie] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098790 ! ncRNA transcription associated with protein coding gene TSS/TES +relationship: negatively_regulates GO:0098790 ! ncRNA transcription associated with protein coding gene TSS/TES +created_by: dos +creation_date: 2015-06-23T18:11:39Z + +[Term] +id: GO:1904389 +name: rod bipolar cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell." [GO_REF:0000086, GOC:TermGenie, PMID:16914133] +is_a: GO:0060040 ! retinal bipolar neuron differentiation +created_by: sl +creation_date: 2015-06-23T19:01:11Z + +[Term] +id: GO:1904390 +name: cone retinal bipolar cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell." [GO_REF:0000086, GOC:TermGenie, PMID:24123365] +synonym: "cone bipolar cell differentiation" EXACT [PMID:14745032] +synonym: "retinal cone bipolar cell differentiation" EXACT [] +is_a: GO:0060040 ! retinal bipolar neuron differentiation +created_by: sl +creation_date: 2015-06-23T19:01:16Z + +[Term] +id: GO:1904391 +name: response to ciliary neurotrophic factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16914133] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: sl +creation_date: 2015-06-23T19:13:04Z + +[Term] +id: GO:1904392 +name: cellular response to ciliary neurotrophic factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16914133] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1904391 ! response to ciliary neurotrophic factor +created_by: sl +creation_date: 2015-06-23T19:13:10Z + +[Term] +id: GO:1904393 +name: regulation of skeletal muscle acetylcholine-gated channel clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1901626 ! regulation of postsynaptic membrane organization +is_a: GO:1903909 ! regulation of receptor clustering +is_a: GO:1904396 ! regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +relationship: regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +created_by: sl +creation_date: 2015-06-23T19:23:25Z + +[Term] +id: GO:1904394 +name: negative regulation of skeletal muscle acetylcholine-gated channel clustering +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "down regulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "down regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "down regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "inhibition of skeletal muscle acetylcholine-gated channel clustering" NARROW [GOC:TermGenie] +synonym: "inhibition of skeletal muscle AChR clustering" NARROW [GOC:TermGenie] +synonym: "inhibition of skeletal muscle nicotinic acetylcholine receptor clustering" NARROW [GOC:TermGenie] +synonym: "negative regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1901627 ! negative regulation of postsynaptic membrane organization +is_a: GO:1903910 ! negative regulation of receptor clustering +is_a: GO:1904393 ! regulation of skeletal muscle acetylcholine-gated channel clustering +is_a: GO:1904397 ! negative regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +relationship: negatively_regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +created_by: sl +creation_date: 2015-06-23T19:23:31Z + +[Term] +id: GO:1904395 +name: positive regulation of skeletal muscle acetylcholine-gated channel clustering +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "activation of skeletal muscle acetylcholine-gated channel clustering" NARROW [GOC:TermGenie] +synonym: "activation of skeletal muscle AChR clustering" NARROW [GOC:TermGenie] +synonym: "activation of skeletal muscle nicotinic acetylcholine receptor clustering" NARROW [GOC:TermGenie] +synonym: "positive regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "positive regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal muscle acetylcholine-gated channel clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal muscle AChR clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1901628 ! positive regulation of postsynaptic membrane organization +is_a: GO:1903911 ! positive regulation of receptor clustering +is_a: GO:1904393 ! regulation of skeletal muscle acetylcholine-gated channel clustering +is_a: GO:1904398 ! positive regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +relationship: positively_regulates GO:0071340 ! skeletal muscle acetylcholine-gated channel clustering +created_by: sl +creation_date: 2015-06-23T19:23:37Z + +[Term] +id: GO:1904396 +name: regulation of neuromuscular junction development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "regulation of NMJ stability" RELATED [GOC:TermGenie] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007528 ! neuromuscular junction development +relationship: regulates GO:0007528 ! neuromuscular junction development +created_by: sl +creation_date: 2015-06-23T19:23:42Z + +[Term] +id: GO:1904397 +name: negative regulation of neuromuscular junction development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "down regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "down regulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "down-regulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "downregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "downregulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "inhibition of neuromuscular junction development" NARROW [GOC:TermGenie] +synonym: "inhibition of neuromuscular junction organization" NARROW [GOC:TermGenie] +synonym: "inhibition of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "inhibition of NMJ stability" RELATED [GOC:TermGenie] +synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "negative regulation of NMJ stability" RELATED [GOC:TermGenie] +is_a: GO:1904396 ! regulation of neuromuscular junction development +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007528 ! neuromuscular junction development +relationship: negatively_regulates GO:0007528 ! neuromuscular junction development +created_by: sl +creation_date: 2015-06-23T19:23:48Z + +[Term] +id: GO:1904398 +name: positive regulation of neuromuscular junction development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] +synonym: "activation of neuromuscular junction development" NARROW [GOC:TermGenie] +synonym: "activation of neuromuscular junction organization" NARROW [GOC:TermGenie] +synonym: "activation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "activation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "positive regulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "up regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "up regulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "up-regulation of NMJ stability" RELATED [GOC:TermGenie] +synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie] +synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] +synonym: "upregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] +synonym: "upregulation of NMJ stability" RELATED [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1904396 ! regulation of neuromuscular junction development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007528 ! neuromuscular junction development +relationship: positively_regulates GO:0007528 ! neuromuscular junction development +created_by: sl +creation_date: 2015-06-23T19:23:54Z + +[Term] +id: GO:1904399 +name: heparan sulfate binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with heparan sulfate." [GO_REF:0000067, GOC:TermGenie, PMID:8567685] +is_a: GO:0005539 ! glycosaminoglycan binding +is_a: GO:0043168 ! anion binding +is_a: GO:1901681 ! sulfur compound binding +created_by: sl +creation_date: 2015-06-23T19:56:54Z + +[Term] +id: GO:1904400 +name: response to Thyroid stimulating hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11238928] +is_a: GO:1904587 ! response to glycoprotein +created_by: sl +creation_date: 2015-06-23T20:57:53Z + +[Term] +id: GO:1904401 +name: cellular response to Thyroid stimulating hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11238928] +is_a: GO:1904400 ! response to Thyroid stimulating hormone +is_a: GO:1904588 ! cellular response to glycoprotein +created_by: sl +creation_date: 2015-06-23T20:57:59Z + +[Term] +id: GO:1904402 +name: response to nocodazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17822405] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-06-23T21:10:45Z + +[Term] +id: GO:1904403 +name: cellular response to nocodazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17822405] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904402 ! response to nocodazole +created_by: sl +creation_date: 2015-06-23T21:10:52Z + +[Term] +id: GO:1904404 +name: response to formaldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:9149109] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-06-23T21:14:04Z + +[Term] +id: GO:1904405 +name: cellular response to formaldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:9149109] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0110096 ! cellular response to aldehyde +is_a: GO:1904404 ! response to formaldehyde +created_by: sl +creation_date: 2015-06-23T21:14:10Z + +[Term] +id: GO:1904406 +name: negative regulation of nitric oxide metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] +synonym: "down regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of nitric oxide metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of nitric oxide metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046209 ! nitric oxide metabolic process +relationship: negatively_regulates GO:0046209 ! nitric oxide metabolic process +created_by: sl +creation_date: 2015-06-24T20:56:41Z + +[Term] +id: GO:1904407 +name: positive regulation of nitric oxide metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] +synonym: "activation of nitric oxide metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of nitric oxide metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046209 ! nitric oxide metabolic process +relationship: positively_regulates GO:0046209 ! nitric oxide metabolic process +created_by: sl +creation_date: 2015-06-24T20:56:47Z + +[Term] +id: GO:1904408 +name: melatonin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with melatonin." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10379923] +is_a: GO:0008144 ! drug binding +is_a: GO:0033218 ! amide binding +is_a: GO:0042562 ! hormone binding +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +created_by: mr +creation_date: 2015-06-25T19:19:53Z + +[Term] +id: GO:1904409 +name: regulation of secretory granule organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] +synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033363 ! secretory granule organization +relationship: regulates GO:0033363 ! secretory granule organization +created_by: sl +creation_date: 2015-06-25T19:40:42Z + +[Term] +id: GO:1904410 +name: negative regulation of secretory granule organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] +synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "down regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "downregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of secretory granule organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of secretory granule organization" NARROW [GOC:TermGenie] +synonym: "inhibition of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1904409 ! regulation of secretory granule organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033363 ! secretory granule organization +relationship: negatively_regulates GO:0033363 ! secretory granule organization +created_by: sl +creation_date: 2015-06-25T19:40:49Z + +[Term] +id: GO:1904411 +name: positive regulation of secretory granule organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] +synonym: "activation of secretory granule organisation" NARROW [GOC:TermGenie] +synonym: "activation of secretory granule organization" NARROW [GOC:TermGenie] +synonym: "activation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "up regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie] +synonym: "upregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1904409 ! regulation of secretory granule organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033363 ! secretory granule organization +relationship: positively_regulates GO:0033363 ! secretory granule organization +created_by: sl +creation_date: 2015-06-25T19:40:55Z + +[Term] +id: GO:1904412 +name: regulation of cardiac ventricle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003231 ! cardiac ventricle development +relationship: regulates GO:0003231 ! cardiac ventricle development +created_by: sl +creation_date: 2015-06-25T19:52:15Z + +[Term] +id: GO:1904413 +name: negative regulation of cardiac ventricle development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] +synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac ventricle development" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904412 ! regulation of cardiac ventricle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003231 ! cardiac ventricle development +relationship: negatively_regulates GO:0003231 ! cardiac ventricle development +created_by: sl +creation_date: 2015-06-25T19:52:21Z + +[Term] +id: GO:1904414 +name: positive regulation of cardiac ventricle development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] +synonym: "activation of cardiac ventricle development" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904412 ! regulation of cardiac ventricle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003231 ! cardiac ventricle development +relationship: positively_regulates GO:0003231 ! cardiac ventricle development +created_by: sl +creation_date: 2015-06-25T19:52:27Z + +[Term] +id: GO:1904415 +name: regulation of xenophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xenophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21617041] +comment: An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype). +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0016241 ! regulation of macroautophagy +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098792 ! xenophagy +relationship: regulates GO:0098792 ! xenophagy +created_by: pad +creation_date: 2015-06-29T12:30:47Z + +[Term] +id: GO:1904416 +name: negative regulation of xenophagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21617041] +comment: An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype). +synonym: "down regulation of xenophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of xenophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of xenophagy" EXACT [GOC:TermGenie] +synonym: "inhibition of xenophagy" NARROW [GOC:TermGenie] +is_a: GO:0002832 ! negative regulation of response to biotic stimulus +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:1904415 ! regulation of xenophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098792 ! xenophagy +relationship: negatively_regulates GO:0098792 ! xenophagy +created_by: pad +creation_date: 2015-06-29T12:30:53Z + +[Term] +id: GO:1904417 +name: positive regulation of xenophagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xenophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21617041] +comment: An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype). +synonym: "activation of xenophagy" NARROW [GOC:TermGenie] +synonym: "up regulation of xenophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of xenophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of xenophagy" EXACT [GOC:TermGenie] +is_a: GO:0002833 ! positive regulation of response to biotic stimulus +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:1904415 ! regulation of xenophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098792 ! xenophagy +relationship: positively_regulates GO:0098792 ! xenophagy +created_by: pad +creation_date: 2015-06-29T12:30:59Z + +[Term] +id: GO:1904418 +name: regulation of telomeric loop formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomeric loop formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of t-loop formation" EXACT [GOC:TermGenie] +is_a: GO:0032204 ! regulation of telomere maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031627 ! telomeric loop formation +relationship: regulates GO:0031627 ! telomeric loop formation +created_by: nc +creation_date: 2015-07-01T10:40:24Z + +[Term] +id: GO:1904419 +name: negative regulation of telomeric loop formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "down regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric loop formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric loop formation" EXACT [GOC:TermGenie] +synonym: "downregulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric loop formation" EXACT [GOC:TermGenie] +synonym: "inhibition of t-loop biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of t-loop formation" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric loop formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of t-loop formation" EXACT [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904418 ! regulation of telomeric loop formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031627 ! telomeric loop formation +relationship: negatively_regulates GO:0031627 ! telomeric loop formation +created_by: nc +creation_date: 2015-07-01T10:40:29Z + +[Term] +id: GO:1904420 +name: positive regulation of telomeric loop formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomeric loop formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "activation of t-loop biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of t-loop formation" NARROW [GOC:TermGenie] +synonym: "activation of telomeric loop formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "up regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric loop formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric loop formation" EXACT [GOC:TermGenie] +synonym: "upregulation of t-loop biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of t-loop formation" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric loop formation" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:1904418 ! regulation of telomeric loop formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031627 ! telomeric loop formation +relationship: positively_regulates GO:0031627 ! telomeric loop formation +created_by: nc +creation_date: 2015-07-01T10:40:35Z + +[Term] +id: GO:1904421 +name: response to D-galactosamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12057922] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-07-02T15:38:20Z + +[Term] +id: GO:1904422 +name: cellular response to D-galactosamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12057922] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904421 ! response to D-galactosamine +created_by: sl +creation_date: 2015-07-02T15:38:36Z + +[Term] +id: GO:1904423 +name: dehydrodolichyl diphosphate synthase complex +namespace: cellular_component +def: "A protein complex which is capable of dehydrodolichyl diphosphate synthase activity." [GO_REF:0000088, GOC:TermGenie, PMID:25066056] +is_a: GO:1990234 ! transferase complex +created_by: ew +creation_date: 2015-07-02T19:51:40Z + +[Term] +id: GO:1904424 +name: regulation of GTP binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of GTP binding." [GO_REF:0000059, GOC:TermGenie, PMID:19066305, PMID:21454546] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005525 ! GTP binding +relationship: regulates GO:0005525 ! GTP binding +created_by: sl +creation_date: 2015-07-02T20:34:44Z + +[Term] +id: GO:1904425 +name: negative regulation of GTP binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding." [GO_REF:0000059, GOC:TermGenie, PMID:19066305, PMID:21454546] +synonym: "down regulation of GTP binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of GTP binding" EXACT [GOC:TermGenie] +synonym: "downregulation of GTP binding" EXACT [GOC:TermGenie] +synonym: "inhibition of GTP binding" NARROW [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1904424 ! regulation of GTP binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005525 ! GTP binding +relationship: negatively_regulates GO:0005525 ! GTP binding +created_by: sl +creation_date: 2015-07-02T20:35:01Z + +[Term] +id: GO:1904426 +name: positive regulation of GTP binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of GTP binding." [GO_REF:0000059, GOC:TermGenie, PMID:19066305, PMID:21454546] +synonym: "activation of GTP binding" NARROW [GOC:TermGenie] +synonym: "up regulation of GTP binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of GTP binding" EXACT [GOC:TermGenie] +synonym: "upregulation of GTP binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1904424 ! regulation of GTP binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005525 ! GTP binding +relationship: positively_regulates GO:0005525 ! GTP binding +created_by: sl +creation_date: 2015-07-02T20:35:07Z + +[Term] +id: GO:1904427 +name: positive regulation of calcium ion transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:22910094] +synonym: "activation of calcium ion membrane transport" NARROW [GOC:TermGenie] +synonym: "activation of calcium ion transmembrane transport" NARROW [GOC:TermGenie] +synonym: "activation of transmembrane calcium transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "positive regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion membrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion transmembrane transport" EXACT [GOC:TermGenie] +synonym: "upregulation of transmembrane calcium transport" EXACT [GOC:TermGenie] +is_a: GO:0051928 ! positive regulation of calcium ion transport +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070588 ! calcium ion transmembrane transport +relationship: positively_regulates GO:0070588 ! calcium ion transmembrane transport +created_by: sl +creation_date: 2015-07-02T20:44:25Z + +[Term] +id: GO:1904428 +name: negative regulation of tubulin deacetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation." [GO_REF:0000058, GOC:TermGenie, PMID:23886946] +synonym: "down regulation of tubulin deacetylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of tubulin deacetylation" EXACT [GOC:TermGenie] +synonym: "downregulation of tubulin deacetylation" EXACT [GOC:TermGenie] +synonym: "inhibition of tubulin deacetylation" NARROW [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:0090043 ! regulation of tubulin deacetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090042 ! tubulin deacetylation +relationship: negatively_regulates GO:0090042 ! tubulin deacetylation +created_by: sart +creation_date: 2015-07-03T14:42:58Z + +[Term] +id: GO:1904429 +name: regulation of t-circle formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of t-circle formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "regulation of telomeric circle formation" EXACT [GOC:TermGenie] +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090656 ! t-circle formation +relationship: regulates GO:0090656 ! t-circle formation +created_by: nc +creation_date: 2015-07-03T15:15:45Z + +[Term] +id: GO:1904430 +name: negative regulation of t-circle formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "down regulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "inhibition of t-circle formation" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric circle formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomeric circle formation" EXACT [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904429 ! regulation of t-circle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090656 ! t-circle formation +relationship: negatively_regulates GO:0090656 ! t-circle formation +created_by: nc +creation_date: 2015-07-03T15:15:52Z + +[Term] +id: GO:1904431 +name: positive regulation of t-circle formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of t-circle formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "activation of t-circle formation" NARROW [GOC:TermGenie] +synonym: "activation of telomeric circle formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric circle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of t-circle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric circle formation" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:1904429 ! regulation of t-circle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090656 ! t-circle formation +relationship: positively_regulates GO:0090656 ! t-circle formation +created_by: nc +creation_date: 2015-07-03T15:15:58Z + +[Term] +id: GO:1904432 +name: regulation of ferrous iron binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferrous iron binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008198 ! ferrous iron binding +relationship: regulates GO:0008198 ! ferrous iron binding +created_by: kom +creation_date: 2015-07-06T13:46:30Z + +[Term] +id: GO:1904433 +name: negative regulation of ferrous iron binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "down regulation of ferrous iron binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrous iron binding" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrous iron binding" EXACT [GOC:TermGenie] +synonym: "inhibition of ferrous iron binding" NARROW [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1904432 ! regulation of ferrous iron binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008198 ! ferrous iron binding +relationship: negatively_regulates GO:0008198 ! ferrous iron binding +created_by: kom +creation_date: 2015-07-06T13:46:36Z + +[Term] +id: GO:1904434 +name: positive regulation of ferrous iron binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ferrous iron binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "activation of ferrous iron binding" NARROW [GOC:TermGenie] +synonym: "up regulation of ferrous iron binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrous iron binding" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrous iron binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1904432 ! regulation of ferrous iron binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008198 ! ferrous iron binding +relationship: positively_regulates GO:0008198 ! ferrous iron binding +created_by: kom +creation_date: 2015-07-06T13:46:42Z + +[Term] +id: GO:1904435 +name: regulation of transferrin receptor binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transferrin receptor binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990459 ! transferrin receptor binding +relationship: regulates GO:1990459 ! transferrin receptor binding +created_by: kom +creation_date: 2015-07-06T13:49:01Z + +[Term] +id: GO:1904436 +name: negative regulation of transferrin receptor binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "down regulation of transferrin receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of transferrin receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of transferrin receptor binding" EXACT [GOC:TermGenie] +synonym: "inhibition of transferrin receptor binding" NARROW [GOC:TermGenie] +is_a: GO:1900121 ! negative regulation of receptor binding +is_a: GO:1904435 ! regulation of transferrin receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990459 ! transferrin receptor binding +relationship: negatively_regulates GO:1990459 ! transferrin receptor binding +created_by: kom +creation_date: 2015-07-06T13:49:07Z + +[Term] +id: GO:1904437 +name: positive regulation of transferrin receptor binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transferrin receptor binding." [GO_REF:0000059, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "activation of transferrin receptor binding" NARROW [GOC:TermGenie] +synonym: "up regulation of transferrin receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of transferrin receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of transferrin receptor binding" EXACT [GOC:TermGenie] +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:1904435 ! regulation of transferrin receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990459 ! transferrin receptor binding +relationship: positively_regulates GO:1990459 ! transferrin receptor binding +created_by: kom +creation_date: 2015-07-06T13:49:13Z + +[Term] +id: GO:1904438 +name: regulation of iron ion import across plasma membrane +namespace: biological_process +alt_id: GO:1903989 +def: "Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "regulation of ferrous iron import across plasma membrane" RELATED [] +synonym: "regulation of ferrous iron import into cell" RELATED [] +is_a: GO:0034759 ! regulation of iron ion transmembrane transport +is_a: GO:0060341 ! regulation of cellular localization +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098711 ! iron ion import across plasma membrane +relationship: regulates GO:0098711 ! iron ion import across plasma membrane +created_by: rl +creation_date: 2015-03-04T14:37:36Z + +[Term] +id: GO:1904439 +name: negative regulation of iron ion import across plasma membrane +namespace: biological_process +alt_id: GO:1903990 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "down regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "down regulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +synonym: "down-regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "down-regulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +synonym: "downregulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "downregulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +synonym: "inhibition of ferrous ion import into cell" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrous iron import across plasma membrane" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "negative regulation of ferrous iron import across plasma membrane" RELATED [] +synonym: "negative regulation of ferrous iron import into cell" RELATED [] +is_a: GO:0034760 ! negative regulation of iron ion transmembrane transport +is_a: GO:1904438 ! regulation of iron ion import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098711 ! iron ion import across plasma membrane +relationship: negatively_regulates GO:0098711 ! iron ion import across plasma membrane +created_by: rl +creation_date: 2015-07-06T13:49:58Z + +[Term] +id: GO:1904440 +name: positive regulation of iron ion import across plasma membrane +namespace: biological_process +alt_id: GO:1903991 +def: "Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:kom, GOC:TermGenie, PMID:18353247] +synonym: "activation of ferrous ion import into cell" NARROW [GOC:TermGenie] +synonym: "activation of ferrous iron import across plasma membrane" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "positive regulation of ferrous iron import across plasma membrane" RELATED [] +synonym: "positive regulation of ferrous iron import into cell" RELATED [] +synonym: "up regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "up regulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +synonym: "up-regulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "up-regulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +synonym: "upregulation of ferrous ion import into cell" RELATED [GOC:TermGenie] +synonym: "upregulation of ferrous iron import across plasma membrane" RELATED [GOC:TermGenie] +is_a: GO:0034761 ! positive regulation of iron ion transmembrane transport +is_a: GO:1904438 ! regulation of iron ion import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098711 ! iron ion import across plasma membrane +relationship: positively_regulates GO:0098711 ! iron ion import across plasma membrane +created_by: rl +creation_date: 2015-07-06T13:50:04Z + +[Term] +id: GO:1904441 +name: regulation of thyroid gland epithelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:17646383] +synonym: "regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990789 ! thyroid gland epithelial cell proliferation +relationship: regulates GO:1990789 ! thyroid gland epithelial cell proliferation +created_by: sl +creation_date: 2015-07-06T15:41:09Z + +[Term] +id: GO:1904442 +name: negative regulation of thyroid gland epithelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:17646383] +synonym: "down regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "down regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "down regulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "down-regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "down-regulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "downregulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "downregulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of thyroid gland epithelial cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904441 ! regulation of thyroid gland epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990789 ! thyroid gland epithelial cell proliferation +relationship: negatively_regulates GO:1990789 ! thyroid gland epithelial cell proliferation +created_by: sl +creation_date: 2015-07-06T15:41:15Z + +[Term] +id: GO:1904443 +name: positive regulation of thyroid gland epithelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:17646383] +synonym: "activation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of thyroid gland epithelial cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "up-regulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "up-regulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of Hurthle cell proliferation" NARROW [GOC:TermGenie] +synonym: "upregulation of thyroid follicular cell proliferation" NARROW [GOC:TermGenie] +synonym: "upregulation of thyroid gland epithelial cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904441 ! regulation of thyroid gland epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990789 ! thyroid gland epithelial cell proliferation +relationship: positively_regulates GO:1990789 ! thyroid gland epithelial cell proliferation +created_by: sl +creation_date: 2015-07-06T15:41:21Z + +[Term] +id: GO:1904444 +name: regulation of establishment of Sertoli cell barrier +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier." [GO_REF:0000058, GOC:TermGenie, PMID:18057314] +synonym: "regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of SCB" EXACT [GOC:TermGenie] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000018 ! regulation of male gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097368 ! establishment of Sertoli cell barrier +relationship: regulates GO:0097368 ! establishment of Sertoli cell barrier +created_by: sl +creation_date: 2015-07-06T16:00:41Z + +[Term] +id: GO:1904445 +name: negative regulation of establishment of Sertoli cell barrier +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier." [GO_REF:0000058, GOC:TermGenie, PMID:18057314] +synonym: "down regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of blood-testis barrier" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of BTB" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of SCB" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of Sertoli cell barrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of SCB" EXACT [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:1904444 ! regulation of establishment of Sertoli cell barrier +is_a: GO:2000019 ! negative regulation of male gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097368 ! establishment of Sertoli cell barrier +relationship: negatively_regulates GO:0097368 ! establishment of Sertoli cell barrier +created_by: sl +creation_date: 2015-07-06T16:00:48Z + +[Term] +id: GO:1904446 +name: positive regulation of establishment of Sertoli cell barrier +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier." [GO_REF:0000058, GOC:TermGenie, PMID:18057314] +synonym: "activation of establishment of blood-testis barrier" NARROW [GOC:TermGenie] +synonym: "activation of establishment of BTB" NARROW [GOC:TermGenie] +synonym: "activation of establishment of SCB" NARROW [GOC:TermGenie] +synonym: "activation of establishment of Sertoli cell barrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of blood-testis barrier" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of BTB" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of SCB" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of Sertoli cell barrier" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:1904444 ! regulation of establishment of Sertoli cell barrier +is_a: GO:2000020 ! positive regulation of male gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097368 ! establishment of Sertoli cell barrier +relationship: positively_regulates GO:0097368 ! establishment of Sertoli cell barrier +created_by: sl +creation_date: 2015-07-06T16:00:54Z + +[Term] +id: GO:1904447 +name: folate import across plasma membrane +namespace: biological_process +def: "The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:19762432] +synonym: "folate import into cell" EXACT [GOC:hal] +synonym: "folic acid import across plasma membrane" RELATED [] +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:0098838 ! folate transmembrane transport +created_by: hal +creation_date: 2015-07-07T15:32:33Z + +[Term] +id: GO:1904448 +name: regulation of aspartate secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aspartate secretion." [GO_REF:0000058, GOC:TermGenie, PMID:2342602] +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:1903530 ! regulation of secretion by cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061528 ! aspartate secretion +relationship: regulates GO:0061528 ! aspartate secretion +created_by: sl +creation_date: 2015-07-07T20:56:57Z + +[Term] +id: GO:1904449 +name: negative regulation of aspartate secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion." [GO_REF:0000058, GOC:TermGenie, PMID:2342602] +synonym: "down regulation of aspartate secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartate secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartate secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of aspartate secretion" NARROW [GOC:TermGenie] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903531 ! negative regulation of secretion by cell +is_a: GO:1904448 ! regulation of aspartate secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061528 ! aspartate secretion +relationship: negatively_regulates GO:0061528 ! aspartate secretion +created_by: sl +creation_date: 2015-07-07T20:57:04Z + +[Term] +id: GO:1904450 +name: positive regulation of aspartate secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aspartate secretion." [GO_REF:0000058, GOC:TermGenie, PMID:2342602] +synonym: "activation of aspartate secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of aspartate secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartate secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartate secretion" EXACT [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903532 ! positive regulation of secretion by cell +is_a: GO:1904448 ! regulation of aspartate secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061528 ! aspartate secretion +relationship: positively_regulates GO:0061528 ! aspartate secretion +created_by: sl +creation_date: 2015-07-07T20:57:10Z + +[Term] +id: GO:1904451 +name: regulation of potassium:proton exchanging ATPase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11897793] +synonym: "regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [] +synonym: "regulation of proton pump activity" BROAD [GOC:TermGenie] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008900 ! potassium:proton exchanging ATPase activity +relationship: regulates GO:0008900 ! potassium:proton exchanging ATPase activity +created_by: sl +creation_date: 2015-07-08T23:00:03Z + +[Term] +id: GO:1904452 +name: negative regulation of potassium:proton exchanging ATPase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11897793] +synonym: "down regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "down regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "down regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "down-regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "down-regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "downregulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "downregulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of (K+ + H+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP phosphohydrolase (H+/K+-exchanging)" NARROW [GOC:TermGenie] +synonym: "inhibition of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "inhibition of H(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of H(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of H+-K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of H+/K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of H+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of H,K-ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "negative regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "negative regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [] +is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity +is_a: GO:1904451 ! regulation of potassium:proton exchanging ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008900 ! potassium:proton exchanging ATPase activity +relationship: negatively_regulates GO:0008900 ! potassium:proton exchanging ATPase activity +created_by: sl +creation_date: 2015-07-08T23:00:09Z + +[Term] +id: GO:1904453 +name: positive regulation of potassium:proton exchanging ATPase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11897793] +synonym: "activation of (K+ + H+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP phosphohydrolase (H+/K+-exchanging)" NARROW [GOC:TermGenie] +synonym: "activation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "activation of H(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of H(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of H+-K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of H+/K+-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of H+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of H,K-ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "positive regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "positive regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [] +synonym: "up regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "up regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "up regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "up-regulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "up-regulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] +synonym: "upregulation of gastric H(+)/K(+) ATPase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] +synonym: "upregulation of H(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of H(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of H,K-ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity +is_a: GO:1904451 ! regulation of potassium:proton exchanging ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008900 ! potassium:proton exchanging ATPase activity +relationship: positively_regulates GO:0008900 ! potassium:proton exchanging ATPase activity +created_by: sl +creation_date: 2015-07-08T23:00:15Z + +[Term] +id: GO:1904456 +name: negative regulation of neuronal action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] +synonym: "down regulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of generation of action potential" RELATED [GOC:TermGenie] +synonym: "inhibition of neuronal action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of generation of action potential" RELATED [GOC:TermGenie] +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:0051970 ! negative regulation of transmission of nerve impulse +is_a: GO:0098908 ! regulation of neuronal action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019228 ! neuronal action potential +relationship: negatively_regulates GO:0019228 ! neuronal action potential +created_by: sl +creation_date: 2015-07-09T18:02:40Z + +[Term] +id: GO:1904457 +name: positive regulation of neuronal action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] +synonym: "activation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "activation of neuronal action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "up regulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of generation of action potential" RELATED [GOC:TermGenie] +synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie] +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:0051971 ! positive regulation of transmission of nerve impulse +is_a: GO:0098908 ! regulation of neuronal action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019228 ! neuronal action potential +relationship: positively_regulates GO:0019228 ! neuronal action potential +created_by: sl +creation_date: 2015-07-09T18:02:46Z + +[Term] +id: GO:1904458 +name: regulation of substance P secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of substance P secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990772 ! substance P secretion +relationship: regulates GO:1990772 ! substance P secretion +created_by: sl +creation_date: 2015-07-09T19:32:50Z + +[Term] +id: GO:1904459 +name: negative regulation of substance P secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +synonym: "down regulation of substance P secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of substance P secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of substance P secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of substance P secretion" NARROW [GOC:TermGenie] +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +is_a: GO:1904458 ! regulation of substance P secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990772 ! substance P secretion +relationship: negatively_regulates GO:1990772 ! substance P secretion +created_by: sl +creation_date: 2015-07-09T19:32:57Z + +[Term] +id: GO:1904460 +name: positive regulation of substance P secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of substance P secretion." [GO_REF:0000058, GOC:TermGenie, PMID:11278900] +synonym: "activation of substance P secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of substance P secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of substance P secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of substance P secretion" EXACT [GOC:TermGenie] +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +is_a: GO:1904458 ! regulation of substance P secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990772 ! substance P secretion +relationship: positively_regulates GO:1990772 ! substance P secretion +created_by: sl +creation_date: 2015-07-09T19:33:03Z + +[Term] +id: GO:1904461 +name: ergosteryl 3-beta-D-glucoside metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside." [GO_REF:0000068, GOC:TermGenie, PMID:26116408] +synonym: "ergosteryl 3-beta-D-glucoside metabolism" EXACT [GOC:TermGenie] +is_a: GO:0008202 ! steroid metabolic process +is_a: GO:0016134 ! saponin metabolic process +is_a: GO:1901804 ! beta-glucoside metabolic process +created_by: mcc +creation_date: 2015-07-09T19:36:19Z + +[Term] +id: GO:1904462 +name: ergosteryl 3-beta-D-glucoside catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside." [GO_REF:0000068, GOC:TermGenie, PMID:26116408] +synonym: "ergosteryl 3-beta-D-glucoside breakdown" EXACT [GOC:TermGenie] +synonym: "ergosteryl 3-beta-D-glucoside catabolism" EXACT [GOC:TermGenie] +synonym: "ergosteryl 3-beta-D-glucoside degradation" EXACT [GOC:TermGenie] +is_a: GO:0006706 ! steroid catabolic process +is_a: GO:0016136 ! saponin catabolic process +is_a: GO:1901805 ! beta-glucoside catabolic process +is_a: GO:1904461 ! ergosteryl 3-beta-D-glucoside metabolic process +created_by: mcc +creation_date: 2015-07-09T19:36:25Z + +[Term] +id: GO:1904463 +name: ergosteryl 3-beta-D-glucoside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside." [GO_REF:0000068, GOC:TermGenie, PMID:26116408] +synonym: "ergosteryl 3-beta-D-glucoside anabolism" EXACT [GOC:TermGenie] +synonym: "ergosteryl 3-beta-D-glucoside biosynthesis" EXACT [GOC:TermGenie] +synonym: "ergosteryl 3-beta-D-glucoside formation" EXACT [GOC:TermGenie] +synonym: "ergosteryl 3-beta-D-glucoside synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006694 ! steroid biosynthetic process +is_a: GO:0016135 ! saponin biosynthetic process +is_a: GO:1901806 ! beta-glucoside biosynthetic process +is_a: GO:1904461 ! ergosteryl 3-beta-D-glucoside metabolic process +created_by: mcc +creation_date: 2015-07-09T19:36:31Z + +[Term] +id: GO:1904464 +name: regulation of matrix metallopeptidase secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +synonym: "regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "regulation of MMP secretion" EXACT [GOC:TermGenie] +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990773 ! matrix metallopeptidase secretion +relationship: regulates GO:1990773 ! matrix metallopeptidase secretion +created_by: sl +creation_date: 2015-07-09T19:46:17Z + +[Term] +id: GO:1904465 +name: negative regulation of matrix metallopeptidase secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +synonym: "down regulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of matrix metallopeptidase secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of MMP secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of MMP secretion" EXACT [GOC:TermGenie] +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:1904464 ! regulation of matrix metallopeptidase secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990773 ! matrix metallopeptidase secretion +relationship: negatively_regulates GO:1990773 ! matrix metallopeptidase secretion +created_by: sl +creation_date: 2015-07-09T19:46:24Z + +[Term] +id: GO:1904466 +name: positive regulation of matrix metallopeptidase secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion." [GO_REF:0000058, GOC:TermGenie, PMID:8679543] +synonym: "activation of matrix metallopeptidase secretion" NARROW [GOC:TermGenie] +synonym: "activation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "activation of MMP secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of MMP secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of matrix metallopeptidase secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of matrix metalloproteinase secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of MMP secretion" EXACT [GOC:TermGenie] +is_a: GO:0050714 ! positive regulation of protein secretion +is_a: GO:1904464 ! regulation of matrix metallopeptidase secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990773 ! matrix metallopeptidase secretion +relationship: positively_regulates GO:1990773 ! matrix metallopeptidase secretion +created_by: sl +creation_date: 2015-07-09T19:46:30Z + +[Term] +id: GO:1904467 +name: regulation of tumor necrosis factor secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tumor necrosis factor secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032680 ! regulation of tumor necrosis factor production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990774 ! tumor necrosis factor secretion +relationship: regulates GO:1990774 ! tumor necrosis factor secretion +created_by: sl +creation_date: 2015-07-09T19:50:02Z + +[Term] +id: GO:1904468 +name: negative regulation of tumor necrosis factor secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "down regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of cachectin secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of TNF secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of TNF superfamily, member 2 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of TNF-alpha secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of Tnfa secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of tumor necrosis factor alpha secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of tumor necrosis factor ligand superfamily member 2 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of tumor necrosis factor secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032720 ! negative regulation of tumor necrosis factor production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1904467 ! regulation of tumor necrosis factor secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990774 ! tumor necrosis factor secretion +relationship: negatively_regulates GO:1990774 ! tumor necrosis factor secretion +created_by: sl +creation_date: 2015-07-09T19:50:08Z + +[Term] +id: GO:1904469 +name: positive regulation of tumor necrosis factor secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "activation of cachectin secretion" NARROW [GOC:TermGenie] +synonym: "activation of TNF secretion" NARROW [GOC:TermGenie] +synonym: "activation of TNF superfamily, member 2 secretion" NARROW [GOC:TermGenie] +synonym: "activation of TNF-alpha secretion" NARROW [GOC:TermGenie] +synonym: "activation of Tnfa secretion" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor alpha secretion" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor ligand superfamily member 2 secretion" NARROW [GOC:TermGenie] +synonym: "activation of tumor necrosis factor secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of cachectin secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of TNF secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of TNF superfamily, member 2 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of TNF-alpha secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of Tnfa secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor alpha secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor ligand superfamily member 2 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of tumor necrosis factor secretion" EXACT [GOC:TermGenie] +is_a: GO:0032760 ! positive regulation of tumor necrosis factor production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1904467 ! regulation of tumor necrosis factor secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990774 ! tumor necrosis factor secretion +relationship: positively_regulates GO:1990774 ! tumor necrosis factor secretion +created_by: sl +creation_date: 2015-07-09T19:50:14Z + +[Term] +id: GO:1904470 +name: regulation of endothelin secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990775 ! endothelin secretion +relationship: regulates GO:1990775 ! endothelin secretion +created_by: sl +creation_date: 2015-07-09T19:57:57Z + +[Term] +id: GO:1904471 +name: negative regulation of endothelin secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "down regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "down regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "down-regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "downregulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of endothelin secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1904470 ! regulation of endothelin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990775 ! endothelin secretion +relationship: negatively_regulates GO:1990775 ! endothelin secretion +created_by: sl +creation_date: 2015-07-09T19:58:03Z + +[Term] +id: GO:1904472 +name: positive regulation of endothelin secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelin secretion." [GO_REF:0000058, GOC:TermGenie, PMID:15560120] +synonym: "activation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "activation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "activation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "activation of endothelin secretion" NARROW [GOC:TermGenie] +synonym: "activation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "activation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "activation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "up-regulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of EDN1 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of EDN2 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of EDN3 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of endothelin secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelin-1 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of endothelin-2 secretion" NARROW [GOC:TermGenie] +synonym: "upregulation of endothelin-3 secretion" NARROW [GOC:TermGenie] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1904470 ! regulation of endothelin secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990775 ! endothelin secretion +relationship: positively_regulates GO:1990775 ! endothelin secretion +created_by: sl +creation_date: 2015-07-09T19:58:10Z + +[Term] +id: GO:1904473 +name: response to L-dopa +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25044243] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +is_a: GO:1904386 ! response to L-phenylalanine derivative +created_by: sl +creation_date: 2015-07-09T20:15:53Z + +[Term] +id: GO:1904474 +name: cellular response to L-dopa +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25044243] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1904387 ! cellular response to L-phenylalanine derivative +is_a: GO:1904473 ! response to L-dopa +created_by: sl +creation_date: 2015-07-09T20:15:59Z + +[Term] +id: GO:1904475 +name: regulation of Ras GTPase binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Ras GTPase binding." [GO_REF:0000059, GOC:TermGenie, PMID:15798216] +synonym: "regulation of Ras interactor activity" RELATED [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017016 ! Ras GTPase binding +relationship: regulates GO:0017016 ! Ras GTPase binding +created_by: sl +creation_date: 2015-07-10T22:47:31Z + +[Term] +id: GO:1904476 +name: negative regulation of Ras GTPase binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Ras GTPase binding." [GO_REF:0000059, GOC:TermGenie, PMID:15798216] +synonym: "down regulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "down regulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "downregulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "downregulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "inhibition of Ras GTPase binding" NARROW [GOC:TermGenie] +synonym: "inhibition of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of Ras interactor activity" RELATED [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:1904475 ! regulation of Ras GTPase binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017016 ! Ras GTPase binding +relationship: negatively_regulates GO:0017016 ! Ras GTPase binding +created_by: sl +creation_date: 2015-07-10T22:47:38Z + +[Term] +id: GO:1904477 +name: positive regulation of Ras GTPase binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Ras GTPase binding." [GO_REF:0000059, GOC:TermGenie, PMID:15798216] +synonym: "activation of Ras GTPase binding" NARROW [GOC:TermGenie] +synonym: "activation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "up regulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ras interactor activity" RELATED [GOC:TermGenie] +synonym: "upregulation of Ras GTPase binding" EXACT [GOC:TermGenie] +synonym: "upregulation of Ras interactor activity" RELATED [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:1904475 ! regulation of Ras GTPase binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017016 ! Ras GTPase binding +relationship: positively_regulates GO:0017016 ! Ras GTPase binding +created_by: sl +creation_date: 2015-07-10T22:47:43Z + +[Term] +id: GO:1904478 +name: regulation of intestinal absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intestinal absorption." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12469120] +is_a: GO:0044058 ! regulation of digestive system process +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050892 ! intestinal absorption +relationship: regulates GO:0050892 ! intestinal absorption +created_by: rl +creation_date: 2015-07-13T15:58:47Z + +[Term] +id: GO:1904479 +name: negative regulation of intestinal absorption +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12469120] +synonym: "down regulation of intestinal absorption" EXACT [GOC:TermGenie] +synonym: "down-regulation of intestinal absorption" EXACT [GOC:TermGenie] +synonym: "downregulation of intestinal absorption" EXACT [GOC:TermGenie] +synonym: "inhibition of intestinal absorption" NARROW [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0060457 ! negative regulation of digestive system process +is_a: GO:1904478 ! regulation of intestinal absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050892 ! intestinal absorption +relationship: negatively_regulates GO:0050892 ! intestinal absorption +created_by: rl +creation_date: 2015-07-13T15:58:54Z + +[Term] +id: GO:1904480 +name: positive regulation of intestinal absorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intestinal absorption." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12469120] +synonym: "activation of intestinal absorption" NARROW [GOC:TermGenie] +synonym: "up regulation of intestinal absorption" EXACT [GOC:TermGenie] +synonym: "up-regulation of intestinal absorption" EXACT [GOC:TermGenie] +synonym: "upregulation of intestinal absorption" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0060456 ! positive regulation of digestive system process +is_a: GO:1904478 ! regulation of intestinal absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050892 ! intestinal absorption +relationship: positively_regulates GO:0050892 ! intestinal absorption +created_by: rl +creation_date: 2015-07-13T15:59:00Z + +[Term] +id: GO:1904481 +name: response to tetrahydrofolate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus." [GO_REF:0000071, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24698160] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: hal +creation_date: 2015-07-14T14:49:17Z + +[Term] +id: GO:1904482 +name: cellular response to tetrahydrofolate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus." [GO_REF:0000071, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24698160] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904481 ! response to tetrahydrofolate +created_by: hal +creation_date: 2015-07-14T14:49:23Z + +[Term] +id: GO:1904483 +name: synthetic cannabinoid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with synthetic cannabinoid." [GO_REF:0000067, GOC:mr, GOC:TermGenie, PMID:10700562] +is_a: GO:0005488 ! binding +created_by: mr +creation_date: 2015-07-14T22:30:09Z + +[Term] +id: GO:1904484 +name: cloacal gland development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421] +is_a: GO:0048732 ! gland development +created_by: mr +creation_date: 2015-07-15T22:14:39Z + +[Term] +id: GO:1904486 +name: response to 17alpha-ethynylestradiol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18805421] +is_a: GO:0009725 ! response to hormone +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:0042493 ! response to drug +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mr +creation_date: 2015-07-15T22:31:36Z + +[Term] +id: GO:1904487 +name: cellular response to 17alpha-ethynylestradiol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18805421] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904486 ! response to 17alpha-ethynylestradiol +created_by: mr +creation_date: 2015-07-15T22:31:42Z + +[Term] +id: GO:1904488 +name: regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process." [GO_REF:0000063, GOC:kmv, GOC:TermGenie, PMID:25961505] +synonym: "regulation of reactive oxygen species metabolic process by activation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by activation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by positive regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by positive regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by stimulation of global transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by up regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by up-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by upregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by activation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by activation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by positive regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by positive regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by positive regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by stimulation of global transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by up regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by up-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by upregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by activation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by activation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by positive regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by positive regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by stimulation of global transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by up regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by up-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by upregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: regulates GO:0072593 ! reactive oxygen species metabolic process +created_by: kmv +creation_date: 2015-07-17T18:11:59Z + +[Term] +id: GO:1904489 +name: regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process." [GO_REF:0000063, GOC:kmv, GOC:TermGenie, PMID:25961505] +synonym: "regulation of reactive oxygen species metabolic process by down regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by down-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by downregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by inhibition of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by inhibition of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by negative regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by negative regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by down regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by down-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by downregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by inhibition of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by inhibition of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by negative regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by negative regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by down regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by down-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by downregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by inhibition of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by inhibition of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by negative regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by negative regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: regulates GO:0072593 ! reactive oxygen species metabolic process +created_by: kmv +creation_date: 2015-07-17T18:12:06Z + +[Term] +id: GO:1904490 +name: negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response." [GO_REF:0000063, GOC:kmv, GOC:TermGenie, PMID:25961505] +synonym: "negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "negative regulation of mtUPR by negative regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: negatively_regulates GO:0034514 ! mitochondrial unfolded protein response +relationship: negatively_regulates GO:0034514 ! mitochondrial unfolded protein response +created_by: kmv +creation_date: 2015-07-17T18:15:13Z + +[Term] +id: GO:1904491 +name: protein localization to ciliary transition zone +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230] +synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie] +synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie] +synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie] +is_a: GO:0061512 ! protein localization to cilium +created_by: kmv +creation_date: 2015-07-17T20:43:21Z + +[Term] +id: GO:1904492 +name: Ac-Asp-Glu binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with Ac-Asp-Glu." [GO_REF:0000067, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24863754] +is_a: GO:0043168 ! anion binding +is_a: GO:1900750 ! oligopeptide binding +created_by: hal +creation_date: 2015-07-20T10:32:49Z + +[Term] +id: GO:1904493 +name: tetrahydrofolyl-poly(glutamate) polymer binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with tetrahydrofolyl-poly(glutamate) polymer." [GO_REF:0000067, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24863754] +is_a: GO:0005488 ! binding +created_by: hal +creation_date: 2015-07-20T10:34:28Z + +[Term] +id: GO:1904494 +name: regulation of substance P secretion, neurotransmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:15292051] +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:1904458 ! regulation of substance P secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990793 ! substance P secretion, neurotransmission +relationship: regulates GO:1990793 ! substance P secretion, neurotransmission +created_by: sl +creation_date: 2015-07-21T19:09:04Z + +[Term] +id: GO:1904495 +name: negative regulation of substance P secretion, neurotransmission +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:15292051] +synonym: "down regulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "down-regulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "downregulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "inhibition of substance P secretion, neurotransmission" NARROW [GOC:TermGenie] +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:1904459 ! negative regulation of substance P secretion +is_a: GO:1904494 ! regulation of substance P secretion, neurotransmission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990793 ! substance P secretion, neurotransmission +relationship: negatively_regulates GO:1990793 ! substance P secretion, neurotransmission +created_by: sl +creation_date: 2015-07-21T19:09:10Z + +[Term] +id: GO:1904496 +name: positive regulation of substance P secretion, neurotransmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:15292051] +synonym: "activation of substance P secretion, neurotransmission" NARROW [GOC:TermGenie] +synonym: "up regulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "up-regulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "upregulation of substance P secretion, neurotransmission" EXACT [GOC:TermGenie] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:1904460 ! positive regulation of substance P secretion +is_a: GO:1904494 ! regulation of substance P secretion, neurotransmission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990793 ! substance P secretion, neurotransmission +relationship: positively_regulates GO:1990793 ! substance P secretion, neurotransmission +created_by: sl +creation_date: 2015-07-21T19:09:16Z + +[Term] +id: GO:1904498 +name: protein localization to mitotic actomyosin contractile ring +namespace: biological_process +def: "Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis." [GO_REF:0000060, GOC:TermGenie, PMID:25688133] +synonym: "protein localisation to actomyosin contractile ring involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "protein localisation to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [GOC:TermGenie] +synonym: "protein localization to actomyosin contractile ring during mitotic cytokinesis" RELATED [] +synonym: "protein localization to actomyosin contractile ring involved in cytokinesis after mitosis" EXACT [GOC:TermGenie] +synonym: "protein localization to actomyosin contractile ring involved in mitotic cytokinesis" EXACT [] +synonym: "protein localization to mitotic actomyosin contractile ring" EXACT [] +is_a: GO:1903047 ! mitotic cell cycle process +is_a: GO:1990179 ! protein localization to actomyosin contractile ring +intersection_of: GO:1990179 ! protein localization to actomyosin contractile ring +intersection_of: part_of GO:0000281 ! mitotic cytokinesis +relationship: part_of GO:0000281 ! mitotic cytokinesis +created_by: mah +creation_date: 2015-07-22T14:30:57Z + +[Term] +id: GO:1904499 +name: regulation of chromatin-mediated maintenance of transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +is_a: GO:1902275 ! regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048096 ! chromatin-mediated maintenance of transcription +relationship: regulates GO:0048096 ! chromatin-mediated maintenance of transcription +created_by: nc +creation_date: 2015-07-24T09:31:08Z + +[Term] +id: GO:1904500 +name: negative regulation of chromatin-mediated maintenance of transcription +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "down regulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +synonym: "down-regulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +synonym: "downregulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +synonym: "inhibition of chromatin-mediated maintenance of transcription" NARROW [GOC:TermGenie] +is_a: GO:1904499 ! regulation of chromatin-mediated maintenance of transcription +is_a: GO:1905268 ! negative regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048096 ! chromatin-mediated maintenance of transcription +relationship: negatively_regulates GO:0048096 ! chromatin-mediated maintenance of transcription +created_by: nc +creation_date: 2015-07-24T09:31:14Z + +[Term] +id: GO:1904501 +name: positive regulation of chromatin-mediated maintenance of transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "activation of chromatin-mediated maintenance of transcription" NARROW [GOC:TermGenie] +synonym: "up regulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +synonym: "upregulation of chromatin-mediated maintenance of transcription" EXACT [GOC:TermGenie] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:1904499 ! regulation of chromatin-mediated maintenance of transcription +is_a: GO:1905269 ! positive regulation of chromatin organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048096 ! chromatin-mediated maintenance of transcription +relationship: positively_regulates GO:0048096 ! chromatin-mediated maintenance of transcription +created_by: nc +creation_date: 2015-07-24T09:31:20Z + +[Term] +id: GO:1904502 +name: regulation of lipophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipophagy." [GO_REF:0000058, GOC:autophagy, GOC:dph, GOC:TermGenie, PMID:25383539] +is_a: GO:0016241 ! regulation of macroautophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061724 ! lipophagy +relationship: regulates GO:0061724 ! lipophagy +created_by: dph +creation_date: 2015-07-24T11:37:12Z + +[Term] +id: GO:1904503 +name: negative regulation of lipophagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy." [GO_REF:0000058, GOC:autophagy, GOC:dph, GOC:TermGenie, PMID:25383539] +synonym: "down regulation of lipophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of lipophagy" EXACT [GOC:TermGenie] +synonym: "inhibition of lipophagy" NARROW [GOC:TermGenie] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:1904502 ! regulation of lipophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061724 ! lipophagy +relationship: negatively_regulates GO:0061724 ! lipophagy +created_by: dph +creation_date: 2015-07-24T11:37:18Z + +[Term] +id: GO:1904504 +name: positive regulation of lipophagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lipophagy." [GO_REF:0000058, GOC:autophagy, GOC:dph, GOC:TermGenie, PMID:25383539] +synonym: "activation of lipophagy" NARROW [GOC:TermGenie] +synonym: "up regulation of lipophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of lipophagy" EXACT [GOC:TermGenie] +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:1904502 ! regulation of lipophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061724 ! lipophagy +relationship: positively_regulates GO:0061724 ! lipophagy +created_by: dph +creation_date: 2015-07-24T11:37:24Z + +[Term] +id: GO:1904505 +name: regulation of telomere maintenance in response to DNA damage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +is_a: GO:0032204 ! regulation of telomere maintenance +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043247 ! telomere maintenance in response to DNA damage +relationship: regulates GO:0043247 ! telomere maintenance in response to DNA damage +created_by: nc +creation_date: 2015-07-24T16:05:55Z + +[Term] +id: GO:1904506 +name: negative regulation of telomere maintenance in response to DNA damage +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "down regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "down regulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA damage response, telomere maintenance" NARROW [GOC:TermGenie] +synonym: "inhibition of telomere maintenance in response to DNA damage" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904505 ! regulation of telomere maintenance in response to DNA damage +is_a: GO:2001021 ! negative regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043247 ! telomere maintenance in response to DNA damage +relationship: negatively_regulates GO:0043247 ! telomere maintenance in response to DNA damage +created_by: nc +creation_date: 2015-07-24T16:06:02Z + +[Term] +id: GO:1904507 +name: positive regulation of telomere maintenance in response to DNA damage +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "activation of DNA damage response, telomere maintenance" NARROW [GOC:TermGenie] +synonym: "activation of telomere maintenance in response to DNA damage" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "up regulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA damage response, telomere maintenance" EXACT [GOC:TermGenie] +synonym: "upregulation of telomere maintenance in response to DNA damage" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:1904505 ! regulation of telomere maintenance in response to DNA damage +is_a: GO:2001022 ! positive regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043247 ! telomere maintenance in response to DNA damage +relationship: positively_regulates GO:0043247 ! telomere maintenance in response to DNA damage +created_by: nc +creation_date: 2015-07-24T16:06:09Z + +[Term] +id: GO:1904508 +name: regulation of protein localization to basolateral plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26115433] +synonym: "regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:1904375 ! regulation of protein localization to cell periphery +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903361 ! protein localization to basolateral plasma membrane +relationship: regulates GO:1903361 ! protein localization to basolateral plasma membrane +created_by: kmv +creation_date: 2015-07-24T17:56:26Z + +[Term] +id: GO:1904509 +name: negative regulation of protein localization to basolateral plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26115433] +synonym: "down regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:1904376 ! negative regulation of protein localization to cell periphery +is_a: GO:1904508 ! regulation of protein localization to basolateral plasma membrane +is_a: GO:1905476 ! negative regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903361 ! protein localization to basolateral plasma membrane +relationship: negatively_regulates GO:1903361 ! protein localization to basolateral plasma membrane +created_by: kmv +creation_date: 2015-07-24T17:56:32Z + +[Term] +id: GO:1904510 +name: positive regulation of protein localization to basolateral plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26115433] +synonym: "activation of protein localisation in basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to basolateral plasma membrane" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in basolateral plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to basolateral plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:1904377 ! positive regulation of protein localization to cell periphery +is_a: GO:1904508 ! regulation of protein localization to basolateral plasma membrane +is_a: GO:1905477 ! positive regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903361 ! protein localization to basolateral plasma membrane +relationship: positively_regulates GO:1903361 ! protein localization to basolateral plasma membrane +created_by: kmv +creation_date: 2015-07-24T17:56:38Z + +[Term] +id: GO:1904511 +name: cytoplasmic microtubule plus-end +namespace: cellular_component +def: "Any microtubule plus-end that is part of a cytoplasmic microtubule." [GO_REF:0000064, GOC:TermGenie, PMID:15772152] +synonym: "growing microtubule plus end of cytoplasmic microtubule" EXACT [GOC:TermGenie] +synonym: "growing microtubule plus end of non-spindle-associated astral microtubule" NARROW [GOC:TermGenie] +synonym: "microtubule plus end of cytoplasmic microtubule" EXACT [GOC:TermGenie] +synonym: "microtubule plus end of non-spindle-associated astral microtubule" NARROW [GOC:TermGenie] +synonym: "microtubule plus-end of cytoplasmic microtubule" EXACT [GOC:TermGenie] +synonym: "microtubule plus-end of non-spindle-associated astral microtubule" NARROW [GOC:TermGenie] +is_a: GO:0035371 ! microtubule plus-end +intersection_of: GO:0035371 ! microtubule plus-end +intersection_of: part_of GO:0005881 ! cytoplasmic microtubule +relationship: part_of GO:0005881 ! cytoplasmic microtubule +created_by: mah +creation_date: 2015-07-27T13:05:11Z + +[Term] +id: GO:1904512 +name: regulation of initiation of premeiotic DNA replication +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication." [GO_REF:0000058, GOC:TermGenie, PMID:25891897] +synonym: "regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +is_a: GO:0030174 ! regulation of DNA-dependent DNA replication initiation +is_a: GO:0033262 ! regulation of nuclear cell cycle DNA replication +is_a: GO:0051445 ! regulation of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072691 ! initiation of premeiotic DNA replication +relationship: regulates GO:0072691 ! initiation of premeiotic DNA replication +created_by: mah +creation_date: 2015-07-28T12:59:17Z + +[Term] +id: GO:1904513 +name: negative regulation of initiation of premeiotic DNA replication +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication." [GO_REF:0000058, GOC:TermGenie, PMID:25891897] +synonym: "down regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "down regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "down regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "down regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "down-regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "down-regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "downregulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "downregulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "downregulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "downregulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "inhibition of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of initiation of premeiotic DNA replication" NARROW [GOC:TermGenie] +synonym: "inhibition of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "inhibition of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "inhibition of premeiotic DNA replication initiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "negative regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +is_a: GO:0032297 ! negative regulation of DNA-dependent DNA replication initiation +is_a: GO:0051447 ! negative regulation of meiotic cell cycle +is_a: GO:1902576 ! negative regulation of nuclear cell cycle DNA replication +is_a: GO:1904512 ! regulation of initiation of premeiotic DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072691 ! initiation of premeiotic DNA replication +relationship: negatively_regulates GO:0072691 ! initiation of premeiotic DNA replication +created_by: mah +creation_date: 2015-07-28T12:59:23Z + +[Term] +id: GO:1904514 +name: positive regulation of initiation of premeiotic DNA replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication." [GO_REF:0000058, GOC:TermGenie, PMID:25891897] +synonym: "activation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "activation of initiation of premeiotic DNA replication" NARROW [GOC:TermGenie] +synonym: "activation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "activation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "activation of premeiotic DNA replication initiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "up regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "up regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "up regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "up regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "up-regulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +synonym: "upregulation of initiation of meiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of initiation of premeiotic DNA replication" EXACT [GOC:TermGenie] +synonym: "upregulation of initiation of premeiotic DNA synthesis" RELATED [GOC:TermGenie] +synonym: "upregulation of meiotic DNA replication initiation" RELATED [GOC:TermGenie] +synonym: "upregulation of premeiotic DNA replication initiation" EXACT [GOC:TermGenie] +is_a: GO:0010571 ! positive regulation of nuclear cell cycle DNA replication +is_a: GO:0032298 ! positive regulation of DNA-dependent DNA replication initiation +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:1904512 ! regulation of initiation of premeiotic DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072691 ! initiation of premeiotic DNA replication +relationship: positively_regulates GO:0072691 ! initiation of premeiotic DNA replication +created_by: mah +creation_date: 2015-07-28T12:59:29Z + +[Term] +id: GO:1904515 +name: positive regulation of TORC2 signaling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of TORC2 signaling." [GO_REF:0000058, GOC:TermGenie, PMID:25590601] +synonym: "activation of TORC2 signal transduction" NARROW [GOC:TermGenie] +synonym: "activation of TORC2 signaling" NARROW [GOC:TermGenie] +synonym: "positive regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "up regulation of TORC2 signaling" EXACT [GOC:TermGenie] +synonym: "up-regulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "up-regulation of TORC2 signaling" EXACT [GOC:TermGenie] +synonym: "upregulation of TORC2 signal transduction" EXACT [GOC:TermGenie] +synonym: "upregulation of TORC2 signaling" EXACT [GOC:TermGenie] +is_a: GO:0032008 ! positive regulation of TOR signaling +is_a: GO:1903939 ! regulation of TORC2 signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038203 ! TORC2 signaling +relationship: positively_regulates GO:0038203 ! TORC2 signaling +created_by: al +creation_date: 2015-07-28T16:09:55Z + +[Term] +id: GO:1904516 +name: myofibroblast cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a myofibroblast cell." [GO_REF:0000085, GOC:TermGenie, PMID:23026405] +synonym: "MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +created_by: sl +creation_date: 2015-07-28T18:29:08Z + +[Term] +id: GO:1904517 +name: MgATP(2-) binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with MgATP(2-)." [GO_REF:0000067, GOC:bhm, GOC:TermGenie, PMID:20086079] +is_a: GO:0005488 ! binding +created_by: bhm +creation_date: 2015-07-29T13:40:02Z + +[Term] +id: GO:1904518 +name: protein localization to cytoplasmic microtubule plus-end +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end." [GO_REF:0000087, GOC:TermGenie, PMID:15772152] +synonym: "protein localisation in cytoplasmic microtubule plus-end" EXACT [GOC:TermGenie] +synonym: "protein localisation to cytoplasmic microtubule plus-end" EXACT [GOC:TermGenie] +synonym: "protein localization in cytoplasmic microtubule plus-end" EXACT [GOC:TermGenie] +is_a: GO:1904825 ! protein localization to microtubule plus-end +is_a: GO:1905755 ! protein localization to cytoplasmic microtubule +created_by: mah +creation_date: 2015-07-29T14:46:05Z + +[Term] +id: GO:1904519 +name: protein localization to microtubule minus-end +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end." [GO_REF:0000087, GOC:TermGenie, PMID:25987607] +synonym: "protein localisation in microtubule minus-end" EXACT [GOC:TermGenie] +synonym: "protein localisation to microtubule minus-end" EXACT [GOC:TermGenie] +synonym: "protein localization in microtubule minus-end" EXACT [GOC:TermGenie] +is_a: GO:1905725 ! protein localization to microtubule end +created_by: mah +creation_date: 2015-07-29T14:46:11Z + +[Term] +id: GO:1904520 +name: regulation of myofibroblast cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:26119034] +synonym: "regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904516 ! myofibroblast cell apoptotic process +relationship: regulates GO:1904516 ! myofibroblast cell apoptotic process +created_by: sl +creation_date: 2015-07-29T15:52:14Z + +[Term] +id: GO:1904521 +name: negative regulation of myofibroblast cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:26119034] +synonym: "down regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of MFB apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of myofibroblast cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:1904520 ! regulation of myofibroblast cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904516 ! myofibroblast cell apoptotic process +relationship: negatively_regulates GO:1904516 ! myofibroblast cell apoptotic process +created_by: sl +creation_date: 2015-07-29T15:52:20Z + +[Term] +id: GO:1904522 +name: positive regulation of myofibroblast cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:26119034] +synonym: "activation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of MFB apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of myofibroblast cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of MFB apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of MFB apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of myofibroblast cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of myofibroblast cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:1904520 ! regulation of myofibroblast cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904516 ! myofibroblast cell apoptotic process +relationship: positively_regulates GO:1904516 ! myofibroblast cell apoptotic process +created_by: sl +creation_date: 2015-07-29T15:52:26Z + +[Term] +id: GO:1904523 +name: regulation of DNA amplification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA amplification." [GO_REF:0000058, GOC:TermGenie, PMID:26195783] +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006277 ! DNA amplification +relationship: regulates GO:0006277 ! DNA amplification +created_by: mcc +creation_date: 2015-07-29T16:24:13Z + +[Term] +id: GO:1904524 +name: negative regulation of DNA amplification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification." [GO_REF:0000058, GOC:TermGenie, PMID:26195783] +synonym: "down regulation of DNA amplification" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA amplification" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA amplification" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA amplification" NARROW [GOC:TermGenie] +is_a: GO:1904523 ! regulation of DNA amplification +is_a: GO:2000279 ! negative regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006277 ! DNA amplification +relationship: negatively_regulates GO:0006277 ! DNA amplification +created_by: mcc +creation_date: 2015-07-29T16:24:19Z + +[Term] +id: GO:1904525 +name: positive regulation of DNA amplification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA amplification." [GO_REF:0000058, GOC:TermGenie, PMID:26195783] +synonym: "activation of DNA amplification" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA amplification" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA amplification" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA amplification" EXACT [GOC:TermGenie] +is_a: GO:1904523 ! regulation of DNA amplification +is_a: GO:2000573 ! positive regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006277 ! DNA amplification +relationship: positively_regulates GO:0006277 ! DNA amplification +created_by: mcc +creation_date: 2015-07-29T16:24:25Z + +[Term] +id: GO:1904526 +name: regulation of microtubule binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008017 ! microtubule binding +relationship: regulates GO:0008017 ! microtubule binding +created_by: als +creation_date: 2015-07-30T10:32:13Z + +[Term] +id: GO:1904527 +name: negative regulation of microtubule binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "down regulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "down regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "down regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "down-regulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "downregulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "downregulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "inhibition of microtubule binding" NARROW [GOC:TermGenie] +synonym: "inhibition of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "inhibition of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "negative regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:1904526 ! regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008017 ! microtubule binding +relationship: negatively_regulates GO:0008017 ! microtubule binding +created_by: als +creation_date: 2015-07-30T10:32:29Z + +[Term] +id: GO:1904528 +name: positive regulation of microtubule binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "activation of microtubule binding" NARROW [GOC:TermGenie] +synonym: "activation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "activation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "positive regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "up regulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "up regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "up regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "up-regulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +synonym: "upregulation of microtubule binding" EXACT [GOC:TermGenie] +synonym: "upregulation of microtubule severing activity" RELATED [GOC:TermGenie] +synonym: "upregulation of microtubule/chromatin interaction" RELATED [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:1904526 ! regulation of microtubule binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008017 ! microtubule binding +relationship: positively_regulates GO:0008017 ! microtubule binding +created_by: als +creation_date: 2015-07-30T10:32:36Z + +[Term] +id: GO:1904529 +name: regulation of actin filament binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin filament binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "regulation of F-actin binding" EXACT [GOC:TermGenie] +is_a: GO:1904616 ! regulation of actin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051015 ! actin filament binding +relationship: regulates GO:0051015 ! actin filament binding +created_by: als +creation_date: 2015-07-30T10:41:49Z + +[Term] +id: GO:1904530 +name: negative regulation of actin filament binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "down regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "down regulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "down regulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "downregulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "downregulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "downregulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "inhibition of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "inhibition of actin filament binding" NARROW [GOC:TermGenie] +synonym: "inhibition of F-actin binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of F-actin binding" EXACT [GOC:TermGenie] +is_a: GO:1904529 ! regulation of actin filament binding +is_a: GO:1904617 ! negative regulation of actin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051015 ! actin filament binding +relationship: negatively_regulates GO:0051015 ! actin filament binding +created_by: als +creation_date: 2015-07-30T10:41:55Z + +[Term] +id: GO:1904531 +name: positive regulation of actin filament binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin filament binding." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:24520051] +synonym: "activation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "activation of actin filament binding" NARROW [GOC:TermGenie] +synonym: "activation of F-actin binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "up regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "up regulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "up regulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of F-actin binding" EXACT [GOC:TermGenie] +synonym: "upregulation of actin cross-linking activity" RELATED [GOC:TermGenie] +synonym: "upregulation of actin filament binding" EXACT [GOC:TermGenie] +synonym: "upregulation of F-actin binding" EXACT [GOC:TermGenie] +is_a: GO:1904529 ! regulation of actin filament binding +is_a: GO:1904618 ! positive regulation of actin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051015 ! actin filament binding +relationship: positively_regulates GO:0051015 ! actin filament binding +created_by: als +creation_date: 2015-07-30T10:42:01Z + +[Term] +id: GO:1904532 +name: obsolete ATP-dependent microtubule motor activity, minus-end-directed involved in microtubule-based movement +namespace: molecular_function +def: "OBSOLETE. Any ATP-dependent microtubule motor activity, minus-end-directed that is involved in microtubule-based movement." [GO_REF:0000061, GOC:TermGenie, PMID:25987607] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: vw +creation_date: 2015-07-31T06:45:48Z + +[Term] +id: GO:1904533 +name: regulation of telomeric loop disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomeric loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "regulation of T loop disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032204 ! regulation of telomere maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090657 ! telomeric loop disassembly +relationship: regulates GO:0090657 ! telomeric loop disassembly +created_by: nc +creation_date: 2015-07-31T17:14:58Z + +[Term] +id: GO:1904534 +name: negative regulation of telomeric loop disassembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "down regulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of T loop disassembly" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric loop disassembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of T loop disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032205 ! negative regulation of telomere maintenance +is_a: GO:1904533 ! regulation of telomeric loop disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090657 ! telomeric loop disassembly +relationship: negatively_regulates GO:0090657 ! telomeric loop disassembly +created_by: nc +creation_date: 2015-07-31T17:15:04Z + +[Term] +id: GO:1904535 +name: positive regulation of telomeric loop disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22579284] +synonym: "activation of T loop disassembly" NARROW [GOC:TermGenie] +synonym: "activation of telomeric loop disassembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "up regulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of T loop disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric loop disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032206 ! positive regulation of telomere maintenance +is_a: GO:1904533 ! regulation of telomeric loop disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090657 ! telomeric loop disassembly +relationship: positively_regulates GO:0090657 ! telomeric loop disassembly +created_by: nc +creation_date: 2015-07-31T17:15:10Z + +[Term] +id: GO:1904536 +name: regulation of mitotic telomere tethering at nuclear periphery +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery." [GO_REF:0000058, GOC:TermGenie, PMID:22959349] +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044820 ! mitotic telomere tethering at nuclear periphery +relationship: regulates GO:0044820 ! mitotic telomere tethering at nuclear periphery +created_by: al +creation_date: 2015-08-04T14:24:26Z + +[Term] +id: GO:1904537 +name: negative regulation of mitotic telomere tethering at nuclear periphery +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery." [GO_REF:0000058, GOC:TermGenie, PMID:22959349] +synonym: "down regulation of mitotic telomere tethering at nuclear periphery" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic telomere tethering at nuclear periphery" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic telomere tethering at nuclear periphery" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic telomere tethering at nuclear periphery" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1904536 ! regulation of mitotic telomere tethering at nuclear periphery +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044820 ! mitotic telomere tethering at nuclear periphery +relationship: negatively_regulates GO:0044820 ! mitotic telomere tethering at nuclear periphery +created_by: al +creation_date: 2015-08-04T14:24:32Z + +[Term] +id: GO:1904538 +name: regulation of glycolytic process through fructose-6-phosphate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, ISBN:0201090910, ISBN:0879010479] +synonym: "regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +is_a: GO:0006110 ! regulation of glycolytic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +relationship: regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +created_by: dph +creation_date: 2015-08-07T11:35:10Z + +[Term] +id: GO:1904539 +name: negative regulation of glycolytic process through fructose-6-phosphate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, ISBN:0201090910, ISBN:0879010479] +synonym: "down regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "down regulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "downregulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "downregulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "inhibition of glycolysis through fructose-6-phosphate" NARROW [GOC:TermGenie] +synonym: "inhibition of glycolytic process through fructose-6-phosphate" NARROW [GOC:TermGenie] +synonym: "negative regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +is_a: GO:0045820 ! negative regulation of glycolytic process +is_a: GO:1904538 ! regulation of glycolytic process through fructose-6-phosphate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +relationship: negatively_regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +created_by: dph +creation_date: 2015-08-07T11:35:16Z + +[Term] +id: GO:1904540 +name: positive regulation of glycolytic process through fructose-6-phosphate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate." [GO_REF:0000058, GOC:dph, GOC:TermGenie, ISBN:0201090910, ISBN:0879010479] +synonym: "activation of glycolysis through fructose-6-phosphate" NARROW [GOC:TermGenie] +synonym: "activation of glycolytic process through fructose-6-phosphate" NARROW [GOC:TermGenie] +synonym: "positive regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "up regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "up regulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "upregulation of glycolysis through fructose-6-phosphate" EXACT [GOC:TermGenie] +synonym: "upregulation of glycolytic process through fructose-6-phosphate" EXACT [GOC:TermGenie] +is_a: GO:0045821 ! positive regulation of glycolytic process +is_a: GO:1904538 ! regulation of glycolytic process through fructose-6-phosphate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +relationship: positively_regulates GO:0061615 ! glycolytic process through fructose-6-phosphate +created_by: dph +creation_date: 2015-08-07T11:35:22Z + +[Term] +id: GO:1904541 +name: fungal-type cell wall disassembly involved in conjugation with cellular fusion +namespace: biological_process +def: "Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion." [GO_REF:0000060, GOC:TermGenie, PMID:25825517] +synonym: "fungal-type cell wall disassembly involved in cell fusion" RELATED [GOC:TermGenie] +synonym: "fungal-type cell wall disassembly involved in mating" RELATED [GOC:TermGenie] +is_a: GO:0070871 ! cell wall organization involved in conjugation with cellular fusion +is_a: GO:0071853 ! fungal-type cell wall disassembly +intersection_of: GO:0071853 ! fungal-type cell wall disassembly +intersection_of: part_of GO:0000747 ! conjugation with cellular fusion +created_by: al +creation_date: 2015-08-10T17:12:51Z + +[Term] +id: GO:1904542 +name: regulation of free ubiquitin chain polymerization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24660806] +comment: An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype). +is_a: GO:0032271 ! regulation of protein polymerization +is_a: GO:0065008 ! regulation of biological quality +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010994 ! free ubiquitin chain polymerization +relationship: regulates GO:0010994 ! free ubiquitin chain polymerization +created_by: pad +creation_date: 2015-08-11T11:44:53Z + +[Term] +id: GO:1904543 +name: negative regulation of free ubiquitin chain polymerization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24660806] +comment: An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype). +synonym: "down regulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +synonym: "down-regulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +synonym: "downregulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +synonym: "inhibition of free ubiquitin chain polymerization" NARROW [GOC:TermGenie] +is_a: GO:0032272 ! negative regulation of protein polymerization +is_a: GO:1904542 ! regulation of free ubiquitin chain polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010994 ! free ubiquitin chain polymerization +relationship: negatively_regulates GO:0010994 ! free ubiquitin chain polymerization +created_by: pad +creation_date: 2015-08-11T11:45:00Z + +[Term] +id: GO:1904544 +name: positive regulation of free ubiquitin chain polymerization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24660806] +comment: An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype). +synonym: "activation of free ubiquitin chain polymerization" NARROW [GOC:TermGenie] +synonym: "up regulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +synonym: "up-regulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +synonym: "upregulation of free ubiquitin chain polymerization" EXACT [GOC:TermGenie] +is_a: GO:0032273 ! positive regulation of protein polymerization +is_a: GO:1904542 ! regulation of free ubiquitin chain polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010994 ! free ubiquitin chain polymerization +relationship: positively_regulates GO:0010994 ! free ubiquitin chain polymerization +created_by: pad +creation_date: 2015-08-11T11:45:06Z + +[Term] +id: GO:1904546 +name: obsolete negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway +namespace: biological_process +def: "OBSOLETE. Any negative regulation of cAMP-dependent protein kinase activity that is involved in negative regulation of glucose mediated signaling pathway." [GO_REF:0000060, GOC:TermGenie, PMID:21118717] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in down regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in down regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in down-regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in down-regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in downregulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in downregulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in inhibition of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in inhibition of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in negative regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of AMPK involved in negative regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling" NARROW [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling" EXACT [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in down regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in down regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in down-regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in down-regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in downregulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in downregulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in inhibition of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in inhibition of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in negative regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA C involved in negative regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in down regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in down regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in down-regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in down-regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in downregulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in downregulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in inhibition of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in inhibition of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in negative regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of PKA involved in negative regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in down regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in down regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in downregulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in downregulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in inhibition of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in inhibition of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in down regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in down regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in down-regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in down-regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in downregulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in downregulation of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in inhibition of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in inhibition of glucose mediated signalling" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in negative regulation of glucose mediated signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of STK22 involved in negative regulation of glucose mediated signalling" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2015-08-12T09:48:46Z + +[Term] +id: GO:1904547 +name: regulation of cellular response to glucose starvation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to glucose starvation." [GO_REF:0000058, GOC:TermGenie, PMID:21118717] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0032107 ! regulation of response to nutrient levels +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042149 ! cellular response to glucose starvation +relationship: regulates GO:0042149 ! cellular response to glucose starvation +created_by: al +creation_date: 2015-08-12T09:57:52Z + +[Term] +id: GO:1904550 +name: response to arachidonic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16382163] +is_a: GO:0070542 ! response to fatty acid +created_by: sl +creation_date: 2015-08-13T20:53:24Z + +[Term] +id: GO:1904551 +name: cellular response to arachidonic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16382163] +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:1904550 ! response to arachidonic acid +created_by: sl +creation_date: 2015-08-13T20:53:31Z + +[Term] +id: GO:1904552 +name: regulation of chemotaxis to arachidonic acid +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid." [GO_REF:0000058, GOC:TermGenie, PMID:16382163] +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034670 ! chemotaxis to arachidonic acid +relationship: regulates GO:0034670 ! chemotaxis to arachidonic acid +created_by: sl +creation_date: 2015-08-13T21:08:14Z + +[Term] +id: GO:1904553 +name: negative regulation of chemotaxis to arachidonic acid +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid." [GO_REF:0000058, GOC:TermGenie, PMID:16382163] +synonym: "down regulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +synonym: "down-regulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +synonym: "downregulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +synonym: "inhibition of chemotaxis to arachidonic acid" NARROW [GOC:TermGenie] +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:1904552 ! regulation of chemotaxis to arachidonic acid +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034670 ! chemotaxis to arachidonic acid +relationship: negatively_regulates GO:0034670 ! chemotaxis to arachidonic acid +created_by: sl +creation_date: 2015-08-13T21:08:20Z + +[Term] +id: GO:1904554 +name: positive regulation of chemotaxis to arachidonic acid +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid." [GO_REF:0000058, GOC:TermGenie, PMID:16382163] +synonym: "activation of chemotaxis to arachidonic acid" NARROW [GOC:TermGenie] +synonym: "up regulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +synonym: "up-regulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +synonym: "upregulation of chemotaxis to arachidonic acid" EXACT [GOC:TermGenie] +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1904552 ! regulation of chemotaxis to arachidonic acid +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034670 ! chemotaxis to arachidonic acid +relationship: positively_regulates GO:0034670 ! chemotaxis to arachidonic acid +created_by: sl +creation_date: 2015-08-13T21:08:27Z + +[Term] +id: GO:1904555 +name: L-proline transmembrane transport +namespace: biological_process +def: "The directed movement of L-proline across a membrane." [GO_REF:0000069, GOC:kmv, GOC:TermGenie] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0035524 ! proline transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: pr +creation_date: 2015-08-14T14:21:06Z + +[Term] +id: GO:1904556 +name: L-tryptophan transmembrane transport +namespace: biological_process +def: "The directed movement of L-tryptophan across a membrane." [GO_REF:0000069, GOC:kmv, GOC:TermGenie] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015827 ! tryptophan transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: pr +creation_date: 2015-08-14T14:21:13Z + +[Term] +id: GO:1904557 +name: L-alanine transmembrane transport +namespace: biological_process +def: "The directed movement of L-alanine across a membrane." [GO_REF:0000069, GOC:kmv, GOC:TermGenie] +is_a: GO:0015808 ! L-alanine transport +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: pr +creation_date: 2015-08-14T14:21:29Z + +[Term] +id: GO:1904558 +name: response to dextromethorphan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25796330] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0014072 ! response to isoquinoline alkaloid +is_a: GO:0042493 ! response to drug +is_a: GO:0045472 ! response to ether +created_by: mr +creation_date: 2015-08-14T16:09:17Z + +[Term] +id: GO:1904559 +name: cellular response to dextromethorphan +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25796330] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071317 ! cellular response to isoquinoline alkaloid +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1904558 ! response to dextromethorphan +created_by: mr +creation_date: 2015-08-14T16:09:24Z + +[Term] +id: GO:1904560 +name: response to diphenidol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25796330] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +is_a: GO:0097305 ! response to alcohol +created_by: mr +creation_date: 2015-08-14T16:09:31Z + +[Term] +id: GO:1904561 +name: cellular response to diphenidol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25796330] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1904560 ! response to diphenidol +created_by: mr +creation_date: 2015-08-14T16:09:37Z + +[Term] +id: GO:1904562 +name: phosphatidylinositol 5-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving phosphatidylinositol 5-phosphate." [GO_REF:0000068, GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:23916588] +synonym: "phosphatidylinositol 5-phosphate metabolism" EXACT [GOC:TermGenie] +is_a: GO:0046488 ! phosphatidylinositol metabolic process +created_by: dph +creation_date: 2015-08-18T16:21:44Z + +[Term] +id: GO:1904563 +name: phosphatidylinositol 5-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate." [GO_REF:0000068, GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:23916588] +synonym: "phosphatidylinositol 5-phosphate anabolism" EXACT [GOC:TermGenie] +synonym: "phosphatidylinositol 5-phosphate biosynthesis" EXACT [GOC:TermGenie] +synonym: "phosphatidylinositol 5-phosphate formation" EXACT [GOC:TermGenie] +synonym: "phosphatidylinositol 5-phosphate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0006661 ! phosphatidylinositol biosynthetic process +is_a: GO:1904562 ! phosphatidylinositol 5-phosphate metabolic process +created_by: dph +creation_date: 2015-08-18T16:21:50Z + +[Term] +id: GO:1904564 +name: Nbp35-Cfd1 ATPase complex +namespace: cellular_component +def: "An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1." [GO_REF:0000088, GOC:bhm, GOC:rb, GOC:TermGenie, PMID:26195633] +comment: An example of this is the yeast Nbp35-Cfd1 complex (IDA). +xref: IntAct:EBI-11666137 +is_a: GO:1904949 ! ATPase complex +is_a: GO:1990229 ! iron-sulfur cluster assembly complex +created_by: rb +creation_date: 2015-08-18T22:50:29Z + +[Term] +id: GO:1904565 +name: response to 1-oleoyl-sn-glycerol 3-phosphate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12139919] +synonym: "response to 1-oleoyl lysophosphatidic acid" EXACT [] +synonym: "response to LPA" EXACT [] +synonym: "response to lysophosphatidic acid" EXACT [] +synonym: "response to oleoyl lysophosphatidic acid" EXACT [] +synonym: "response to oleoyl-L-alpha-lysophosphatidic acid" EXACT [] +is_a: GO:0033993 ! response to lipid +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-08-19T15:36:48Z + +[Term] +id: GO:1904566 +name: cellular response to 1-oleoyl-sn-glycerol 3-phosphate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12139919] +synonym: "cellular response to 1-oleoyl lysophosphatidic acid" EXACT [] +synonym: "cellular response to LPA" EXACT [] +synonym: "cellular response to lysophosphatidic acid" EXACT [] +synonym: "cellular response to oleoyl lysophosphatidic acid" EXACT [] +synonym: "cellular response to oleoyl-L-alpha-lysophosphatidic acid" EXACT [] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904565 ! response to 1-oleoyl-sn-glycerol 3-phosphate +created_by: sl +creation_date: 2015-08-19T15:37:05Z + +[Term] +id: GO:1904567 +name: response to wortmannin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20629186] +synonym: "response to wartmannin" EXACT [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-08-19T16:22:28Z + +[Term] +id: GO:1904568 +name: cellular response to wortmannin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20629186] +synonym: "cellular response to wartmannin" EXACT [] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904567 ! response to wortmannin +created_by: sl +creation_date: 2015-08-19T16:22:34Z + +[Term] +id: GO:1904569 +name: regulation of selenocysteine incorporation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of selenocysteine incorporation." [GO_REF:0000058, GOC:TermGenie, PMID:21685449] +is_a: GO:0006448 ! regulation of translational elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001514 ! selenocysteine incorporation +relationship: regulates GO:0001514 ! selenocysteine incorporation +created_by: sl +creation_date: 2015-08-19T17:26:38Z + +[Term] +id: GO:1904570 +name: negative regulation of selenocysteine incorporation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation." [GO_REF:0000058, GOC:TermGenie, PMID:21685449] +synonym: "down regulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +synonym: "down-regulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +synonym: "downregulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +synonym: "inhibition of selenocysteine incorporation" NARROW [GOC:TermGenie] +is_a: GO:0045900 ! negative regulation of translational elongation +is_a: GO:1904569 ! regulation of selenocysteine incorporation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001514 ! selenocysteine incorporation +relationship: negatively_regulates GO:0001514 ! selenocysteine incorporation +created_by: sl +creation_date: 2015-08-19T17:26:44Z + +[Term] +id: GO:1904571 +name: positive regulation of selenocysteine incorporation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation." [GO_REF:0000058, GOC:TermGenie, PMID:21685449] +synonym: "activation of selenocysteine incorporation" NARROW [GOC:TermGenie] +synonym: "up regulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +synonym: "up-regulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +synonym: "upregulation of selenocysteine incorporation" EXACT [GOC:TermGenie] +is_a: GO:0045901 ! positive regulation of translational elongation +is_a: GO:1904569 ! regulation of selenocysteine incorporation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001514 ! selenocysteine incorporation +relationship: positively_regulates GO:0001514 ! selenocysteine incorporation +created_by: sl +creation_date: 2015-08-19T17:26:50Z + +[Term] +id: GO:1904572 +name: negative regulation of mRNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:19716792] +synonym: "down regulation of mRNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of mRNA binding" NARROW [GOC:TermGenie] +is_a: GO:1902415 ! regulation of mRNA binding +is_a: GO:1905215 ! negative regulation of RNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003729 ! mRNA binding +relationship: negatively_regulates GO:0003729 ! mRNA binding +created_by: sl +creation_date: 2015-08-19T17:51:03Z + +[Term] +id: GO:1904573 +name: regulation of selenocysteine insertion sequence binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding." [GO_REF:0000059, GOC:TermGenie, PMID:19716792] +synonym: "regulation of SECIS binding" EXACT [GOC:TermGenie] +is_a: GO:1902415 ! regulation of mRNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035368 ! selenocysteine insertion sequence binding +relationship: regulates GO:0035368 ! selenocysteine insertion sequence binding +created_by: sl +creation_date: 2015-08-19T17:51:09Z + +[Term] +id: GO:1904574 +name: negative regulation of selenocysteine insertion sequence binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding." [GO_REF:0000059, GOC:TermGenie, PMID:19716792] +synonym: "down regulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "down regulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +synonym: "downregulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "downregulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +synonym: "inhibition of SECIS binding" NARROW [GOC:TermGenie] +synonym: "inhibition of selenocysteine insertion sequence binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of SECIS binding" EXACT [GOC:TermGenie] +is_a: GO:1904572 ! negative regulation of mRNA binding +is_a: GO:1904573 ! regulation of selenocysteine insertion sequence binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035368 ! selenocysteine insertion sequence binding +relationship: negatively_regulates GO:0035368 ! selenocysteine insertion sequence binding +created_by: sl +creation_date: 2015-08-19T17:51:15Z + +[Term] +id: GO:1904575 +name: positive regulation of selenocysteine insertion sequence binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding." [GO_REF:0000059, GOC:TermGenie, PMID:19716792] +synonym: "activation of SECIS binding" NARROW [GOC:TermGenie] +synonym: "activation of selenocysteine insertion sequence binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "up regulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "up regulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +synonym: "upregulation of SECIS binding" EXACT [GOC:TermGenie] +synonym: "upregulation of selenocysteine insertion sequence binding" EXACT [GOC:TermGenie] +is_a: GO:1902416 ! positive regulation of mRNA binding +is_a: GO:1904573 ! regulation of selenocysteine insertion sequence binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035368 ! selenocysteine insertion sequence binding +relationship: positively_regulates GO:0035368 ! selenocysteine insertion sequence binding +created_by: sl +creation_date: 2015-08-19T17:51:21Z + +[Term] +id: GO:1904576 +name: response to tunicamycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23106379] +is_a: GO:0046677 ! response to antibiotic +created_by: sl +creation_date: 2015-08-19T18:01:52Z + +[Term] +id: GO:1904577 +name: cellular response to tunicamycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23106379] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:1904576 ! response to tunicamycin +created_by: sl +creation_date: 2015-08-19T18:01:58Z + +[Term] +id: GO:1904578 +name: response to thapsigargin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23106379] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0033993 ! response to lipid +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-08-19T18:06:22Z + +[Term] +id: GO:1904579 +name: cellular response to thapsigargin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23106379] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904578 ! response to thapsigargin +created_by: sl +creation_date: 2015-08-19T18:06:28Z + +[Term] +id: GO:1904580 +name: regulation of intracellular mRNA localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intracellular mRNA localization." [GO_REF:0000058, GOC:TermGenie, PMID:21471000] +synonym: "regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008298 ! intracellular mRNA localization +relationship: regulates GO:0008298 ! intracellular mRNA localization +created_by: sl +creation_date: 2015-08-19T23:40:25Z + +[Term] +id: GO:1904581 +name: negative regulation of intracellular mRNA localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization." [GO_REF:0000058, GOC:TermGenie, PMID:21471000] +synonym: "down regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "down regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "down regulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "down regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "down regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "down regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "down-regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "down-regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "downregulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "downregulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "downregulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment and maintenance of intracellular RNA localization" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular mRNA localisation" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular mRNA localization" NARROW [GOC:TermGenie] +synonym: "inhibition of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA localization, intracellular" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "negative regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "negative regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "negative regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1904580 ! regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008298 ! intracellular mRNA localization +relationship: negatively_regulates GO:0008298 ! intracellular mRNA localization +created_by: sl +creation_date: 2015-08-19T23:40:32Z + +[Term] +id: GO:1904582 +name: positive regulation of intracellular mRNA localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization." [GO_REF:0000058, GOC:TermGenie, PMID:21471000] +synonym: "activation of establishment and maintenance of intracellular RNA localization" NARROW [GOC:TermGenie] +synonym: "activation of intracellular mRNA localisation" NARROW [GOC:TermGenie] +synonym: "activation of intracellular mRNA localization" NARROW [GOC:TermGenie] +synonym: "activation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "activation of mRNA localization, intracellular" NARROW [GOC:TermGenie] +synonym: "activation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "positive regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "positive regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "positive regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "up regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "up regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "up regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "up regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "up regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "up-regulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "up-regulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +synonym: "upregulation of establishment and maintenance of intracellular RNA localization" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular mRNA localisation" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular mRNA localization" EXACT [GOC:TermGenie] +synonym: "upregulation of intracellular mRNA positioning" NARROW [GOC:TermGenie] +synonym: "upregulation of mRNA localization, intracellular" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA positioning, intracellular" NARROW [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1904580 ! regulation of intracellular mRNA localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008298 ! intracellular mRNA localization +relationship: positively_regulates GO:0008298 ! intracellular mRNA localization +created_by: sl +creation_date: 2015-08-19T23:40:38Z + +[Term] +id: GO:1904583 +name: response to polyamine macromolecule +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20805360] +synonym: "response to polyamine" EXACT [] +synonym: "response to polyamines" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: sl +creation_date: 2015-08-20T14:35:26Z + +[Term] +id: GO:1904584 +name: cellular response to polyamine macromolecule +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20805360] +synonym: "cellular response to polyamine" EXACT [] +synonym: "cellular response to polyamines" EXACT [] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1904583 ! response to polyamine macromolecule +created_by: sl +creation_date: 2015-08-20T14:35:32Z + +[Term] +id: GO:1904585 +name: response to putrescine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20805360] +synonym: "response to 1,4-Butanediamine" EXACT [] +synonym: "response to 1,4-Diaminobutane" EXACT [] +synonym: "response to tetramethylenediamine" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +created_by: sl +creation_date: 2015-08-20T14:35:39Z + +[Term] +id: GO:1904586 +name: cellular response to putrescine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20805360] +synonym: "cellular response to 1,4-Butanediamine" EXACT [] +synonym: "cellular response to 1,4-Diaminobutane" EXACT [] +synonym: "cellular response to tetramethylenediamine" EXACT [] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1904585 ! response to putrescine +created_by: sl +creation_date: 2015-08-20T14:35:45Z + +[Term] +id: GO:1904587 +name: response to glycoprotein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] +synonym: "response to glycoproteins" EXACT [] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-08-20T16:46:24Z + +[Term] +id: GO:1904588 +name: cellular response to glycoprotein +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] +synonym: "cellular response to glycoproteins" EXACT [] +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904587 ! response to glycoprotein +created_by: sl +creation_date: 2015-08-20T16:46:30Z + +[Term] +id: GO:1904589 +name: regulation of protein import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein import." [GO_REF:0000058, GOC:TermGenie, PMID:11406629] +synonym: "regulation of protein uptake" EXACT [GOC:TermGenie] +is_a: GO:0051223 ! regulation of protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017038 ! protein import +relationship: regulates GO:0017038 ! protein import +created_by: sl +creation_date: 2015-08-20T21:26:30Z + +[Term] +id: GO:1904590 +name: negative regulation of protein import +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein import." [GO_REF:0000058, GOC:TermGenie, PMID:11406629] +synonym: "down regulation of protein import" EXACT [GOC:TermGenie] +synonym: "down regulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein import" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "downregulation of protein import" EXACT [GOC:TermGenie] +synonym: "downregulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "inhibition of protein import" NARROW [GOC:TermGenie] +synonym: "inhibition of protein uptake" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein uptake" EXACT [GOC:TermGenie] +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:1904589 ! regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017038 ! protein import +relationship: negatively_regulates GO:0017038 ! protein import +created_by: sl +creation_date: 2015-08-20T21:26:36Z + +[Term] +id: GO:1904591 +name: positive regulation of protein import +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein import." [GO_REF:0000058, GOC:TermGenie, PMID:11406629] +synonym: "activation of protein import" NARROW [GOC:TermGenie] +synonym: "activation of protein uptake" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "up regulation of protein import" EXACT [GOC:TermGenie] +synonym: "up regulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein import" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein uptake" EXACT [GOC:TermGenie] +synonym: "upregulation of protein import" EXACT [GOC:TermGenie] +synonym: "upregulation of protein uptake" EXACT [GOC:TermGenie] +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:1904589 ! regulation of protein import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017038 ! protein import +relationship: positively_regulates GO:0017038 ! protein import +created_by: sl +creation_date: 2015-08-20T21:26:42Z + +[Term] +id: GO:1904592 +name: positive regulation of protein refolding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein refolding." [GO_REF:0000058, GOC:TermGenie, PMID:11360998] +synonym: "activation of heat shock protein activity" RELATED [GOC:TermGenie] +synonym: "activation of protein refolding" NARROW [GOC:TermGenie] +synonym: "positive regulation of heat shock protein activity" RELATED [GOC:TermGenie] +synonym: "up regulation of heat shock protein activity" RELATED [GOC:TermGenie] +synonym: "up regulation of protein refolding" EXACT [GOC:TermGenie] +synonym: "up-regulation of heat shock protein activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein refolding" EXACT [GOC:TermGenie] +synonym: "upregulation of heat shock protein activity" RELATED [GOC:TermGenie] +synonym: "upregulation of protein refolding" EXACT [GOC:TermGenie] +is_a: GO:0061083 ! regulation of protein refolding +is_a: GO:1903334 ! positive regulation of protein folding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042026 ! protein refolding +relationship: positively_regulates GO:0042026 ! protein refolding +created_by: sl +creation_date: 2015-08-21T18:11:16Z + +[Term] +id: GO:1904593 +name: prostaglandin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with prostaglandin." [GO_REF:0000067, GOC:TermGenie, PMID:21445266] +is_a: GO:0005504 ! fatty acid binding +is_a: GO:0050542 ! icosanoid binding +created_by: sl +creation_date: 2015-08-21T18:53:31Z + +[Term] +id: GO:1904594 +name: regulation of termination of RNA polymerase II transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription." [GO_REF:0000058, GOC:TermGenie, PMID:25417108] +synonym: "regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "regulation of RNA polymerase II transcription termination" EXACT [GOC:TermGenie] +synonym: "regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "regulation of transcription termination from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006369 ! termination of RNA polymerase II transcription +relationship: regulates GO:0006369 ! termination of RNA polymerase II transcription +created_by: al +creation_date: 2015-08-25T08:56:06Z + +[Term] +id: GO:1904595 +name: positive regulation of termination of RNA polymerase II transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription." [GO_REF:0000058, GOC:TermGenie, PMID:25417108] +synonym: "activation of RNA 3'-end formation by RNA polymerase II" NARROW [GOC:TermGenie] +synonym: "activation of RNA polymerase II transcription termination" NARROW [GOC:TermGenie] +synonym: "activation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "activation of termination of RNA polymerase II transcription" NARROW [GOC:TermGenie] +synonym: "activation of transcription termination from Pol II promoter" NARROW [GOC:TermGenie] +synonym: "activation of transcription termination from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA polymerase II transcription termination" EXACT [GOC:TermGenie] +synonym: "positive regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription termination from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA polymerase II transcription termination" EXACT [GOC:TermGenie] +synonym: "up regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "up regulation of termination of RNA polymerase II transcription" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription termination from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA polymerase II transcription termination" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of termination of RNA polymerase II transcription" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription termination from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA 3'-end formation by RNA polymerase II" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA polymerase II transcription termination" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA polymerase II transcription termination factor activity" RELATED [GOC:TermGenie] +synonym: "upregulation of termination of RNA polymerase II transcription" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription termination from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of transcription termination from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:0060566 ! positive regulation of DNA-templated transcription, termination +is_a: GO:1904594 ! regulation of termination of RNA polymerase II transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006369 ! termination of RNA polymerase II transcription +relationship: positively_regulates GO:0006369 ! termination of RNA polymerase II transcription +created_by: al +creation_date: 2015-08-25T08:56:14Z + +[Term] +id: GO:1904596 +name: regulation of connective tissue replacement involved in inflammatory response wound healing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:18245812] +synonym: "regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:0106014 ! regulation of inflammatory response to wounding +is_a: GO:1905203 ! regulation of connective tissue replacement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +relationship: regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +created_by: krc +creation_date: 2015-08-25T20:52:24Z + +[Term] +id: GO:1904597 +name: negative regulation of connective tissue replacement involved in inflammatory response wound healing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:18245812] +synonym: "down regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "down regulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "down regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "down-regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "down-regulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "down-regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "downregulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "downregulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "downregulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "inhibition of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "inhibition of connective tissue replacement involved in inflammatory response wound healing" NARROW [GOC:TermGenie] +synonym: "inhibition of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "negative regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "negative regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:0106015 ! negative regulation of inflammatory response to wounding +is_a: GO:1904596 ! regulation of connective tissue replacement involved in inflammatory response wound healing +is_a: GO:1905204 ! negative regulation of connective tissue replacement +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +relationship: negatively_regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +created_by: krc +creation_date: 2015-08-25T20:52:30Z + +[Term] +id: GO:1904598 +name: positive regulation of connective tissue replacement involved in inflammatory response wound healing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing." [GO_REF:0000058, GOC:krc, GOC:TermGenie, PMID:18245812] +synonym: "activation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "activation of connective tissue replacement involved in inflammatory response wound healing" NARROW [GOC:TermGenie] +synonym: "activation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "positive regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "positive regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "up regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "up regulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "up regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "up-regulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "up-regulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "up-regulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +synonym: "upregulation of connective tissue replacement during inflammatory response" RELATED [GOC:TermGenie] +synonym: "upregulation of connective tissue replacement involved in inflammatory response wound healing" EXACT [GOC:TermGenie] +synonym: "upregulation of fibrosis during inflammatory response" NARROW [GOC:TermGenie] +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:0106016 ! positive regulation of inflammatory response to wounding +is_a: GO:1904596 ! regulation of connective tissue replacement involved in inflammatory response wound healing +is_a: GO:1905205 ! positive regulation of connective tissue replacement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +relationship: positively_regulates GO:0002248 ! connective tissue replacement involved in inflammatory response wound healing +created_by: krc +creation_date: 2015-08-25T20:52:36Z + +[Term] +id: GO:1904599 +name: advanced glycation end-product binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with advanced glycation end-product." [GO_REF:0000067, GOC:krc, GOC:TermGenie, PMID:1650387] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: krc +creation_date: 2015-08-25T23:39:32Z + +[Term] +id: GO:1904600 +name: actin fusion focus assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus." [GO_REF:0000079, GOC:TermGenie, PMID:25825517] +synonym: "actin fusion focus formation" EXACT [GOC:TermGenie] +is_a: GO:0022414 ! reproductive process +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0030036 ! actin cytoskeleton organization +relationship: part_of GO:0000747 ! conjugation with cellular fusion +created_by: al +creation_date: 2015-08-26T10:34:48Z + +[Term] +id: GO:1904601 +name: protein localization to actin fusion focus +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an actin fusion focus." [GO_REF:0000087, GOC:TermGenie, PMID:25825517] +synonym: "protein localisation in actin fusion focus" EXACT [GOC:TermGenie] +synonym: "protein localisation to actin fusion focus" EXACT [GOC:TermGenie] +synonym: "protein localization in actin fusion focus" EXACT [GOC:TermGenie] +is_a: GO:1903119 ! protein localization to actin cytoskeleton +is_a: GO:1903260 ! protein localization to mating projection tip +created_by: al +creation_date: 2015-08-26T10:36:22Z + +[Term] +id: GO:1904602 +name: serotonin-activated cation-selective channel complex +namespace: cellular_component +def: "A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16116092] +comment: An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay). +synonym: "5-HT-3 receptor complex" EXACT [] +synonym: "5-HT3 receptor complex" EXACT [] +synonym: "5-hydroxytryptamine receptor 3 complex" EXACT [] +synonym: "5HT3 receptor complex" EXACT [] +synonym: "serotonin receptor complex" BROAD [] +is_a: GO:0034703 ! cation channel complex +is_a: GO:0098878 ! neurotransmitter receptor complex +created_by: bhm +creation_date: 2015-08-26T13:19:49Z + +[Term] +id: GO:1904603 +name: regulation of advanced glycation end-product receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity." [GO_REF:0000059, GOC:krc, GOC:TermGenie, PMID:16503878] +synonym: "regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "regulation of RAGE activity" EXACT [GOC:TermGenie] +is_a: GO:0010469 ! regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050785 ! advanced glycation end-product receptor activity +relationship: regulates GO:0050785 ! advanced glycation end-product receptor activity +created_by: krc +creation_date: 2015-08-26T16:24:49Z + +[Term] +id: GO:1904604 +name: negative regulation of advanced glycation end-product receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity." [GO_REF:0000059, GOC:krc, GOC:TermGenie, PMID:16503878] +synonym: "down regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "downregulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "inhibition of advanced glycation end-product receptor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of AGE receptor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of RAGE activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of RAGE activity" EXACT [GOC:TermGenie] +is_a: GO:1904603 ! regulation of advanced glycation end-product receptor activity +is_a: GO:2000272 ! negative regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050785 ! advanced glycation end-product receptor activity +relationship: negatively_regulates GO:0050785 ! advanced glycation end-product receptor activity +created_by: krc +creation_date: 2015-08-26T16:24:56Z + +[Term] +id: GO:1904605 +name: positive regulation of advanced glycation end-product receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity." [GO_REF:0000059, GOC:krc, GOC:TermGenie, PMID:16503878] +synonym: "activation of advanced glycation end-product receptor activity" NARROW [GOC:TermGenie] +synonym: "activation of AGE receptor activity" NARROW [GOC:TermGenie] +synonym: "activation of RAGE activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "up regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RAGE activity" EXACT [GOC:TermGenie] +synonym: "upregulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of AGE receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RAGE activity" EXACT [GOC:TermGenie] +is_a: GO:1904603 ! regulation of advanced glycation end-product receptor activity +is_a: GO:2000273 ! positive regulation of signaling receptor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050785 ! advanced glycation end-product receptor activity +relationship: positively_regulates GO:0050785 ! advanced glycation end-product receptor activity +created_by: krc +creation_date: 2015-08-26T16:25:02Z + +[Term] +id: GO:1904606 +name: fat cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416] +synonym: "adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "fat cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0006915 ! apoptotic process +created_by: sl +creation_date: 2015-08-27T18:13:06Z + +[Term] +id: GO:1904608 +name: response to monosodium L-glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21389115] +is_a: GO:1904008 ! response to monosodium glutamate +created_by: sl +creation_date: 2015-08-27T18:43:08Z + +[Term] +id: GO:1904609 +name: cellular response to monosodium L-glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21389115] +is_a: GO:1904009 ! cellular response to monosodium glutamate +is_a: GO:1904608 ! response to monosodium L-glutamate +created_by: sl +creation_date: 2015-08-27T18:43:14Z + +[Term] +id: GO:1904610 +name: response to 3,3',4,4',5-pentachlorobiphenyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +synonym: "response to PCB 126" EXACT [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0042493 ! response to drug +created_by: sl +creation_date: 2015-08-27T18:52:49Z + +[Term] +id: GO:1904611 +name: cellular response to 3,3',4,4',5-pentachlorobiphenyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +synonym: "cellular response to PCB 126" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1904610 ! response to 3,3',4,4',5-pentachlorobiphenyl +created_by: sl +creation_date: 2015-08-27T18:52:55Z + +[Term] +id: GO:1904612 +name: response to 2,3,7,8-tetrachlorodibenzodioxine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +synonym: "response to dioxin" EXACT [] +synonym: "response to TCDD" EXACT [] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014070 ! response to organic cyclic compound +created_by: sl +creation_date: 2015-08-27T19:01:52Z + +[Term] +id: GO:1904613 +name: cellular response to 2,3,7,8-tetrachlorodibenzodioxine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +synonym: "cellular response to dioxin" EXACT [] +synonym: "cellular response to TCDD" EXACT [] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1904612 ! response to 2,3,7,8-tetrachlorodibenzodioxine +created_by: sl +creation_date: 2015-08-27T19:01:58Z + +[Term] +id: GO:1904614 +name: response to biphenyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0060992 ! response to fungicide +created_by: sl +creation_date: 2015-08-27T19:08:43Z + +[Term] +id: GO:1904615 +name: cellular response to biphenyl +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23196670] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1904614 ! response to biphenyl +created_by: sl +creation_date: 2015-08-27T19:08:49Z + +[Term] +id: GO:1904616 +name: regulation of actin binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin binding." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003779 ! actin binding +relationship: regulates GO:0003779 ! actin binding +created_by: mr +creation_date: 2015-08-27T19:08:56Z + +[Term] +id: GO:1904617 +name: negative regulation of actin binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin binding." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "down regulation of actin binding" EXACT [GOC:TermGenie] +synonym: "down regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "down-regulation of actin binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "downregulation of actin binding" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "inhibition of actin binding" NARROW [GOC:TermGenie] +synonym: "inhibition of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:1904616 ! regulation of actin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003779 ! actin binding +relationship: negatively_regulates GO:0003779 ! actin binding +created_by: mr +creation_date: 2015-08-27T19:09:02Z + +[Term] +id: GO:1904618 +name: positive regulation of actin binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin binding." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "activation of actin binding" NARROW [GOC:TermGenie] +synonym: "activation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "up regulation of actin binding" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "up-regulation of actin binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane associated actin binding" NARROW [GOC:TermGenie] +synonym: "upregulation of actin binding" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane associated actin binding" NARROW [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:1904616 ! regulation of actin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003779 ! actin binding +relationship: positively_regulates GO:0003779 ! actin binding +created_by: mr +creation_date: 2015-08-27T19:09:08Z + +[Term] +id: GO:1904619 +name: response to dimethyl sulfoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12873812] +synonym: "response to DMSO" EXACT [] +is_a: GO:0010033 ! response to organic substance +is_a: GO:0042493 ! response to drug +created_by: sl +creation_date: 2015-08-27T19:13:49Z + +[Term] +id: GO:1904620 +name: cellular response to dimethyl sulfoxide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:12873812] +synonym: "cellular response to DMSO" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:1904619 ! response to dimethyl sulfoxide +created_by: sl +creation_date: 2015-08-27T19:14:07Z + +[Term] +id: GO:1904621 +name: regulation of actin-dependent ATPase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin-dependent ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0043462 ! regulation of ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030898 ! actin-dependent ATPase activity +relationship: regulates GO:0030898 ! actin-dependent ATPase activity +created_by: mr +creation_date: 2015-08-27T19:37:18Z + +[Term] +id: GO:1904622 +name: negative regulation of actin-dependent ATPase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin-dependent ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "down regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of actin-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of actin-dependent ATPase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:1904621 ! regulation of actin-dependent ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030898 ! actin-dependent ATPase activity +relationship: negatively_regulates GO:0030898 ! actin-dependent ATPase activity +created_by: mr +creation_date: 2015-08-27T19:37:24Z + +[Term] +id: GO:1904623 +name: positive regulation of actin-dependent ATPase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin-dependent ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8621557] +synonym: "activation of actin-activated ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of actin-dependent ATPase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of actin-activated ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of actin-dependent ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:1904621 ! regulation of actin-dependent ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030898 ! actin-dependent ATPase activity +relationship: positively_regulates GO:0030898 ! actin-dependent ATPase activity +created_by: mr +creation_date: 2015-08-27T19:37:30Z + +[Term] +id: GO:1904624 +name: regulation of glycine secretion, neurotransmission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:22988142] +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0051955 ! regulation of amino acid transport +is_a: GO:0060092 ! regulation of synaptic transmission, glycinergic +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061537 ! glycine secretion, neurotransmission +relationship: regulates GO:0061537 ! glycine secretion, neurotransmission +created_by: hjd +creation_date: 2015-08-27T20:03:38Z + +[Term] +id: GO:1904625 +name: negative regulation of glycine secretion, neurotransmission +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:22988142] +synonym: "down regulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "down-regulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "downregulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "inhibition of glycine secretion, neurotransmission" NARROW [GOC:TermGenie] +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:0060093 ! negative regulation of synaptic transmission, glycinergic +is_a: GO:1904624 ! regulation of glycine secretion, neurotransmission +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061537 ! glycine secretion, neurotransmission +relationship: negatively_regulates GO:0061537 ! glycine secretion, neurotransmission +created_by: hjd +creation_date: 2015-08-27T20:03:44Z + +[Term] +id: GO:1904626 +name: positive regulation of glycine secretion, neurotransmission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission." [GO_REF:0000058, GOC:TermGenie, PMID:22988142] +synonym: "activation of glycine secretion, neurotransmission" NARROW [GOC:TermGenie] +synonym: "up regulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "up-regulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +synonym: "upregulation of glycine secretion, neurotransmission" EXACT [GOC:TermGenie] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:0060094 ! positive regulation of synaptic transmission, glycinergic +is_a: GO:1904624 ! regulation of glycine secretion, neurotransmission +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061537 ! glycine secretion, neurotransmission +relationship: positively_regulates GO:0061537 ! glycine secretion, neurotransmission +created_by: hjd +creation_date: 2015-08-27T20:03:49Z + +[Term] +id: GO:1904627 +name: response to phorbol 13-acetate 12-myristate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:2200903] +synonym: "response to phorbol 12-tetradecanoate 13-acetate" EXACT [] +synonym: "response to PMA" EXACT [] +synonym: "response to tetradecanoylphorbol acetate" EXACT [] +synonym: "response to TPA" EXACT [] +is_a: GO:0033993 ! response to lipid +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-08-28T13:44:03Z + +[Term] +id: GO:1904628 +name: cellular response to phorbol 13-acetate 12-myristate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:2200903] +synonym: "cellular response to phorbol 12-tetradecanoate 13-acetate" EXACT [] +synonym: "cellular response to response to PMA" EXACT [] +synonym: "cellular response to tetradecanoylphorbol acetate" EXACT [] +synonym: "cellular response to TPA" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904627 ! response to phorbol 13-acetate 12-myristate +created_by: sl +creation_date: 2015-08-28T13:44:10Z + +[Term] +id: GO:1904629 +name: response to diterpene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:19765580] +is_a: GO:0033993 ! response to lipid +created_by: sl +creation_date: 2015-08-28T13:52:37Z + +[Term] +id: GO:1904630 +name: cellular response to diterpene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:19765580] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1904629 ! response to diterpene +created_by: sl +creation_date: 2015-08-28T13:52:43Z + +[Term] +id: GO:1904631 +name: response to glucoside +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16842873] +synonym: "response to glucosides" EXACT [] +is_a: GO:1903416 ! response to glycoside +created_by: sl +creation_date: 2015-08-28T14:01:31Z + +[Term] +id: GO:1904632 +name: cellular response to glucoside +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16842873] +synonym: "cellular response to glucosides" EXACT [] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904631 ! response to glucoside +created_by: sl +creation_date: 2015-08-28T14:01:37Z + +[Term] +id: GO:1904633 +name: regulation of glomerular visceral epithelial cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:23692924] +synonym: "regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +relationship: regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +created_by: sl +creation_date: 2015-08-28T14:14:44Z + +[Term] +id: GO:1904634 +name: negative regulation of glomerular visceral epithelial cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:23692924] +synonym: "down regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of glomerular podocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of glomerular visceral epithelial cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of podocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:1904633 ! regulation of glomerular visceral epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +relationship: negatively_regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +created_by: sl +creation_date: 2015-08-28T14:14:50Z + +[Term] +id: GO:1904635 +name: positive regulation of glomerular visceral epithelial cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:23692924] +synonym: "activation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of glomerular podocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of glomerular visceral epithelial cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of podocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of glomerular podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of glomerular podocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of glomerular visceral epithelial cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of glomerular visceral epithelial cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of podocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of podocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:1904633 ! regulation of glomerular visceral epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +relationship: positively_regulates GO:1903210 ! glomerular visceral epithelial cell apoptotic process +created_by: sl +creation_date: 2015-08-28T14:14:56Z + +[Term] +id: GO:1904636 +name: response to ionomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17516843] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:0070542 ! response to fatty acid +created_by: sl +creation_date: 2015-08-31T14:39:18Z + +[Term] +id: GO:1904637 +name: cellular response to ionomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17516843] +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1904636 ! response to ionomycin +created_by: sl +creation_date: 2015-08-31T14:39:25Z + +[Term] +id: GO:1904638 +name: response to resveratrol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23555824] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0035634 ! response to stilbenoid +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-08-31T17:07:38Z + +[Term] +id: GO:1904639 +name: cellular response to resveratrol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23555824] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904638 ! response to resveratrol +created_by: sl +creation_date: 2015-08-31T17:07:44Z + +[Term] +id: GO:1904640 +name: response to methionine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:17716000] +is_a: GO:0043200 ! response to amino acid +created_by: sl +creation_date: 2015-08-31T17:23:56Z + +[Term] +id: GO:1904641 +name: response to dinitrophenol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24336883] +synonym: "response to dinitrophenols" RELATED [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-08-31T20:13:12Z + +[Term] +id: GO:1904642 +name: cellular response to dinitrophenol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24336883] +synonym: "cellular response to dinitrophenols" RELATED [] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904641 ! response to dinitrophenol +created_by: sl +creation_date: 2015-08-31T20:13:18Z + +[Term] +id: GO:1904643 +name: response to curcumin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24755072] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-08-31T20:38:11Z + +[Term] +id: GO:1904644 +name: cellular response to curcumin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24755072] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071362 ! cellular response to ether +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904643 ! response to curcumin +created_by: sl +creation_date: 2015-08-31T20:38:17Z + +[Term] +id: GO:1904645 +name: response to amyloid-beta +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23555824] +synonym: "response to beta-amyloid" EXACT [] +synonym: "response to beta-amyloids" RELATED [] +is_a: GO:1901652 ! response to peptide +created_by: sl +creation_date: 2015-08-31T20:44:43Z + +[Term] +id: GO:1904646 +name: cellular response to amyloid-beta +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23555824] +synonym: "cellular response to beta-amyloid" EXACT [] +synonym: "cellular response to beta-amyloids" RELATED [] +is_a: GO:1901653 ! cellular response to peptide +is_a: GO:1904645 ! response to amyloid-beta +created_by: sl +creation_date: 2015-08-31T20:44:49Z + +[Term] +id: GO:1904647 +name: response to rotenone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18538940] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0017085 ! response to insecticide +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901654 ! response to ketone +created_by: sl +creation_date: 2015-08-31T20:55:32Z + +[Term] +id: GO:1904648 +name: cellular response to rotenone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18538940] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1904647 ! response to rotenone +created_by: sl +creation_date: 2015-08-31T20:55:39Z + +[Term] +id: GO:1904649 +name: regulation of fat cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] +synonym: "regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904606 ! fat cell apoptotic process +relationship: regulates GO:1904606 ! fat cell apoptotic process +created_by: sl +creation_date: 2015-08-31T20:59:28Z + +[Term] +id: GO:1904650 +name: negative regulation of fat cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] +synonym: "down regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of adipocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of adipose cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of fat cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:1904649 ! regulation of fat cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904606 ! fat cell apoptotic process +relationship: negatively_regulates GO:1904606 ! fat cell apoptotic process +created_by: sl +creation_date: 2015-08-31T20:59:34Z + +[Term] +id: GO:1904651 +name: positive regulation of fat cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] +synonym: "activation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of adipocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of adipose cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of fat cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of fat cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:1904649 ! regulation of fat cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904606 ! fat cell apoptotic process +relationship: positively_regulates GO:1904606 ! fat cell apoptotic process +created_by: sl +creation_date: 2015-08-31T20:59:40Z + +[Term] +id: GO:1904652 +name: protein localization to cell division site involved in cell separation after cytokinesis +namespace: biological_process +def: "Any protein localization to cell division site that is involved in cell separation after cytokinesis." [GO_REF:0000060, GOC:TermGenie, PMID:25411334] +is_a: GO:0072741 ! protein localization to cell division site +intersection_of: GO:0072741 ! protein localization to cell division site +intersection_of: part_of GO:0000920 ! septum digestion after cytokinesis +relationship: part_of GO:0000920 ! septum digestion after cytokinesis +created_by: vw +creation_date: 2015-09-01T21:04:45Z + +[Term] +id: GO:1904653 +name: regulation of lung alveolus development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lung alveolus development." [GO_REF:0000058, GOC:TermGenie, PMID:23962064] +synonym: "regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "regulation of alveologenesis" EXACT [GOC:TermGenie] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048286 ! lung alveolus development +relationship: regulates GO:0048286 ! lung alveolus development +created_by: sl +creation_date: 2015-09-03T22:44:44Z + +[Term] +id: GO:1904654 +name: negative regulation of lung alveolus development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development." [GO_REF:0000058, GOC:TermGenie, PMID:23962064] +synonym: "down regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "down regulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of lung alveolus development" EXACT [GOC:TermGenie] +synonym: "down-regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of lung alveolus development" EXACT [GOC:TermGenie] +synonym: "downregulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of lung alveolus development" EXACT [GOC:TermGenie] +synonym: "inhibition of alveolarization" NARROW [GOC:TermGenie] +synonym: "inhibition of alveologenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of lung alveolus development" NARROW [GOC:TermGenie] +synonym: "negative regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "negative regulation of alveologenesis" EXACT [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904653 ! regulation of lung alveolus development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048286 ! lung alveolus development +relationship: negatively_regulates GO:0048286 ! lung alveolus development +created_by: sl +creation_date: 2015-09-03T22:44:50Z + +[Term] +id: GO:1904655 +name: positive regulation of lung alveolus development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lung alveolus development." [GO_REF:0000058, GOC:TermGenie, PMID:23962064] +synonym: "activation of alveolarization" NARROW [GOC:TermGenie] +synonym: "activation of alveologenesis" NARROW [GOC:TermGenie] +synonym: "activation of lung alveolus development" NARROW [GOC:TermGenie] +synonym: "positive regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "positive regulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "up regulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of lung alveolus development" EXACT [GOC:TermGenie] +synonym: "up-regulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of lung alveolus development" EXACT [GOC:TermGenie] +synonym: "upregulation of alveolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of alveologenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of lung alveolus development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904653 ! regulation of lung alveolus development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048286 ! lung alveolus development +relationship: positively_regulates GO:0048286 ! lung alveolus development +created_by: sl +creation_date: 2015-09-03T22:44:56Z + +[Term] +id: GO:1904656 +name: regulation of sensory perception of sweet taste +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sensory perception of sweet taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "regulation of sweet taste perception" EXACT [GOC:TermGenie] +is_a: GO:0051931 ! regulation of sensory perception +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050916 ! sensory perception of sweet taste +relationship: regulates GO:0050916 ! sensory perception of sweet taste +created_by: mr +creation_date: 2015-09-04T16:43:12Z + +[Term] +id: GO:1904657 +name: negative regulation of sensory perception of sweet taste +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "down regulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "down regulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "down-regulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "down-regulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "downregulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "downregulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "inhibition of sensory perception of sweet taste" NARROW [GOC:TermGenie] +synonym: "inhibition of sweet taste perception" NARROW [GOC:TermGenie] +synonym: "negative regulation of sweet taste perception" EXACT [GOC:TermGenie] +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:1904656 ! regulation of sensory perception of sweet taste +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050916 ! sensory perception of sweet taste +relationship: negatively_regulates GO:0050916 ! sensory perception of sweet taste +created_by: mr +creation_date: 2015-09-04T16:43:18Z + +[Term] +id: GO:1904658 +name: positive regulation of sensory perception of sweet taste +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "activation of sensory perception of sweet taste" NARROW [GOC:TermGenie] +synonym: "activation of sweet taste perception" NARROW [GOC:TermGenie] +synonym: "positive regulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "up regulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "up regulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "up-regulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "up-regulation of sweet taste perception" EXACT [GOC:TermGenie] +synonym: "upregulation of sensory perception of sweet taste" EXACT [GOC:TermGenie] +synonym: "upregulation of sweet taste perception" EXACT [GOC:TermGenie] +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:1904656 ! regulation of sensory perception of sweet taste +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050916 ! sensory perception of sweet taste +relationship: positively_regulates GO:0050916 ! sensory perception of sweet taste +created_by: mr +creation_date: 2015-09-04T16:43:24Z + +[Term] +id: GO:1904659 +name: glucose transmembrane transport +namespace: biological_process +alt_id: GO:0015758 +def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] +synonym: "glucose transport" RELATED [] +is_a: GO:0008645 ! hexose transmembrane transport +created_by: vw +creation_date: 2015-09-04T17:20:16Z + +[Term] +id: GO:1904660 +name: regulation of sensory perception of bitter taste +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sensory perception of bitter taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "regulation of bitter taste perception" EXACT [GOC:TermGenie] +is_a: GO:0051931 ! regulation of sensory perception +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050913 ! sensory perception of bitter taste +relationship: regulates GO:0050913 ! sensory perception of bitter taste +created_by: mr +creation_date: 2015-09-04T17:54:10Z + +[Term] +id: GO:1904661 +name: negative regulation of sensory perception of bitter taste +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "down regulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "down regulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +synonym: "down-regulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "down-regulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +synonym: "downregulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "downregulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +synonym: "inhibition of bitter taste perception" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory perception of bitter taste" NARROW [GOC:TermGenie] +synonym: "negative regulation of bitter taste perception" EXACT [GOC:TermGenie] +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:1904660 ! regulation of sensory perception of bitter taste +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050913 ! sensory perception of bitter taste +relationship: negatively_regulates GO:0050913 ! sensory perception of bitter taste +created_by: mr +creation_date: 2015-09-04T17:54:17Z + +[Term] +id: GO:1904662 +name: positive regulation of sensory perception of bitter taste +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:1716172] +synonym: "activation of bitter taste perception" NARROW [GOC:TermGenie] +synonym: "activation of sensory perception of bitter taste" NARROW [GOC:TermGenie] +synonym: "positive regulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "up regulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "up regulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +synonym: "up-regulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "up-regulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +synonym: "upregulation of bitter taste perception" EXACT [GOC:TermGenie] +synonym: "upregulation of sensory perception of bitter taste" EXACT [GOC:TermGenie] +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:1904660 ! regulation of sensory perception of bitter taste +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050913 ! sensory perception of bitter taste +relationship: positively_regulates GO:0050913 ! sensory perception of bitter taste +created_by: mr +creation_date: 2015-09-04T17:54:22Z + +[Term] +id: GO:1904663 +name: regulation of N-terminal peptidyl-methionine acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] +is_a: GO:1901983 ! regulation of protein acetylation +is_a: GO:1903317 ! regulation of protein maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +relationship: regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +created_by: vw +creation_date: 2015-09-07T19:18:49Z + +[Term] +id: GO:1904664 +name: negative regulation of N-terminal peptidyl-methionine acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] +is_a: GO:1901984 ! negative regulation of protein acetylation +is_a: GO:1903318 ! negative regulation of protein maturation +is_a: GO:1904663 ! regulation of N-terminal peptidyl-methionine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +relationship: negatively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +created_by: vw +creation_date: 2015-09-07T19:18:56Z + +[Term] +id: GO:1904665 +name: positive regulation of N-terminal peptidyl-methionine acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] +is_a: GO:1901985 ! positive regulation of protein acetylation +is_a: GO:1903319 ! positive regulation of protein maturation +is_a: GO:1904663 ! regulation of N-terminal peptidyl-methionine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +relationship: positively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation +created_by: vw +creation_date: 2015-09-07T19:19:02Z + +[Term] +id: GO:1904666 +name: regulation of ubiquitin protein ligase activity +namespace: biological_process +alt_id: GO:1903834 +def: "Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, GOC:vw, PMID:10921876, PMID:26216882] +synonym: "regulation of APC-fizzy related complex activity" NARROW [] +synonym: "regulation of E3" RELATED [GOC:TermGenie] +synonym: "regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061630 ! ubiquitin protein ligase activity +relationship: regulates GO:0061630 ! ubiquitin protein ligase activity +created_by: dph +creation_date: 2015-09-08T15:26:59Z + +[Term] +id: GO:1904667 +name: negative regulation of ubiquitin protein ligase activity +namespace: biological_process +alt_id: GO:0060564 +alt_id: GO:1904190 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:tb, GOC:TermGenie, PMID:26216882] +synonym: "down regulation of E3" RELATED [GOC:TermGenie] +synonym: "down regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of E3" RELATED [GOC:TermGenie] +synonym: "down-regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of E3" RELATED [GOC:TermGenie] +synonym: "downregulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of E3" RELATED [GOC:TermGenie] +synonym: "inhibition of protein ubiquitination activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquitin ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquitin protein ligase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of anaphase-promoting complex activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of APC activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of APC-Cdc20 complex activity" NARROW [] +synonym: "negative regulation of APC-fizzy related complex activity" NARROW [] +synonym: "negative regulation of APC/C activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of cyclosome activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] +synonym: "negative regulation of E3" RELATED [GOC:TermGenie] +synonym: "negative regulation of mitotic anaphase-promoting complex activity" RELATED [GOC:vw] +synonym: "negative regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +is_a: GO:0051444 ! negative regulation of ubiquitin-protein transferase activity +is_a: GO:1904666 ! regulation of ubiquitin protein ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061630 ! ubiquitin protein ligase activity +relationship: negatively_regulates GO:0061630 ! ubiquitin protein ligase activity +created_by: dph +creation_date: 2015-09-08T15:27:05Z + +[Term] +id: GO:1904668 +name: positive regulation of ubiquitin protein ligase activity +namespace: biological_process +alt_id: GO:0007092 +alt_id: GO:0051488 +alt_id: GO:0090623 +alt_id: GO:1903835 +def: "Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, GOC:vw, PMID:10921876, PMID:26216882] +synonym: "activation of anaphase-promoting complex activity" NARROW [] +synonym: "activation of APC-Cdc20 complex activity" NARROW [] +synonym: "activation of APC-fizzy related complex activity" NARROW [] +synonym: "activation of E3" RELATED [GOC:TermGenie] +synonym: "activation of protein ubiquitination activity" NARROW [GOC:TermGenie] +synonym: "activation of ubiquitin ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of ubiquitin protein ligase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of APC-fizzy related complex activity" NARROW [] +synonym: "positive regulation of E3" RELATED [GOC:TermGenie] +synonym: "positive regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ubiquitin ligase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] +synonym: "up regulation of E3" RELATED [GOC:TermGenie] +synonym: "up regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of E3" RELATED [GOC:TermGenie] +synonym: "up-regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] +synonym: "upregulation of E3" RELATED [GOC:TermGenie] +synonym: "upregulation of protein ubiquitination activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] +is_a: GO:0051443 ! positive regulation of ubiquitin-protein transferase activity +is_a: GO:1904666 ! regulation of ubiquitin protein ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061630 ! ubiquitin protein ligase activity +relationship: positively_regulates GO:0061630 ! ubiquitin protein ligase activity +created_by: dph +creation_date: 2015-09-08T15:27:11Z + +[Term] +id: GO:1904669 +name: ATP export +namespace: biological_process +def: "The directed movement of ATP out of a cell or organelle." [GO_REF:0000074, GOC:TermGenie, PMID:24286344] +synonym: "ATP efflux" RELATED [] +is_a: GO:0015867 ! ATP transport +is_a: GO:0046618 ! drug export +created_by: tb +creation_date: 2015-09-09T16:33:06Z + +[Term] +id: GO:1904670 +name: actin filament polymerization involved in mitotic actomyosin contractile ring assembly +namespace: biological_process +def: "Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly." [GO_REF:0000060, GOC:TermGenie, PMID:24127216] +is_a: GO:0030041 ! actin filament polymerization +is_a: GO:1903479 ! mitotic actomyosin contractile ring assembly actin filament organization +intersection_of: GO:0030041 ! actin filament polymerization +intersection_of: part_of GO:1903475 ! mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2015-09-09T20:05:56Z + +[Term] +id: GO:1904671 +name: negative regulation of cell differentiation involved in stem cell population maintenance +namespace: biological_process +def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] +synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie] +synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +intersection_of: GO:0045596 ! negative regulation of cell differentiation +intersection_of: part_of GO:0019827 ! stem cell population maintenance +relationship: part_of GO:0019827 ! stem cell population maintenance +created_by: tb +creation_date: 2015-09-12T00:46:08Z + +[Term] +id: GO:1904672 +name: regulation of somatic stem cell population maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +is_a: GO:2000036 ! regulation of stem cell population maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035019 ! somatic stem cell population maintenance +relationship: regulates GO:0035019 ! somatic stem cell population maintenance +created_by: rph +creation_date: 2015-09-14T08:40:19Z + +[Term] +id: GO:1904673 +name: negative regulation of somatic stem cell population maintenance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "inhibition of somatic stem cell population maintenance" NARROW [GOC:TermGenie] +is_a: GO:1902455 ! negative regulation of stem cell population maintenance +is_a: GO:1904672 ! regulation of somatic stem cell population maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035019 ! somatic stem cell population maintenance +relationship: negatively_regulates GO:0035019 ! somatic stem cell population maintenance +created_by: rph +creation_date: 2015-09-14T08:40:25Z + +[Term] +id: GO:1904674 +name: positive regulation of somatic stem cell population maintenance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "activation of somatic stem cell population maintenance" NARROW [GOC:TermGenie] +synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] +is_a: GO:1902459 ! positive regulation of stem cell population maintenance +is_a: GO:1904672 ! regulation of somatic stem cell population maintenance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035019 ! somatic stem cell population maintenance +relationship: positively_regulates GO:0035019 ! somatic stem cell population maintenance +created_by: rph +creation_date: 2015-09-14T08:40:32Z + +[Term] +id: GO:1904675 +name: regulation of somatic stem cell division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:2000035 ! regulation of stem cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048103 ! somatic stem cell division +relationship: regulates GO:0048103 ! somatic stem cell division +created_by: rph +creation_date: 2015-09-14T08:47:22Z + +[Term] +id: GO:1904676 +name: negative regulation of somatic stem cell division +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "inhibition of somatic stem cell division" NARROW [GOC:TermGenie] +synonym: "inhibition of somatic stem cell renewal" NARROW [GOC:TermGenie] +synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:0051782 ! negative regulation of cell division +is_a: GO:1904675 ! regulation of somatic stem cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048103 ! somatic stem cell division +relationship: negatively_regulates GO:0048103 ! somatic stem cell division +created_by: rph +creation_date: 2015-09-14T08:47:28Z + +[Term] +id: GO:1904677 +name: positive regulation of somatic stem cell division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] +synonym: "activation of somatic stem cell division" NARROW [GOC:TermGenie] +synonym: "activation of somatic stem cell renewal" NARROW [GOC:TermGenie] +synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie] +synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:0051781 ! positive regulation of cell division +is_a: GO:1904675 ! regulation of somatic stem cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048103 ! somatic stem cell division +relationship: positively_regulates GO:0048103 ! somatic stem cell division +created_by: rph +creation_date: 2015-09-14T08:47:34Z + +[Term] +id: GO:1904678 +name: alpha-aminoacyl-tRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with alpha-aminoacyl-tRNA." [GO_REF:0000067, GOC:TermGenie, ISBN:155581073X] +synonym: "aminoacyl-tRNA binding" RELATED [] +is_a: GO:0003723 ! RNA binding +created_by: hjd +creation_date: 2015-09-18T16:44:17Z + +[Term] +id: GO:1904679 +name: myo-inositol import across plasma membrane +namespace: biological_process +alt_id: GO:0097357 +def: "The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:9560432] +synonym: "myo-inositol import into cell" EXACT [] +is_a: GO:0015798 ! myo-inositol transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: al +creation_date: 2012-07-03T06:22:05Z + +[Term] +id: GO:1904680 +name: peptide transmembrane transporter activity +namespace: molecular_function +alt_id: GO:0015197 +alt_id: GO:0015637 +def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw] +synonym: "peptide transporter activity" RELATED [] +synonym: "peptide uptake permease activity" RELATED [] +xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" +is_a: GO:0042887 ! amide transmembrane transporter activity +created_by: tb +creation_date: 2015-09-22T18:50:41Z + +[Term] +id: GO:1904681 +name: response to 3-methylcholanthrene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9224771] +is_a: GO:1903165 ! response to polycyclic arene +created_by: mr +creation_date: 2015-09-22T19:50:03Z + +[Term] +id: GO:1904682 +name: cellular response to 3-methylcholanthrene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:9224771] +is_a: GO:1903166 ! cellular response to polycyclic arene +is_a: GO:1904681 ! response to 3-methylcholanthrene +created_by: mr +creation_date: 2015-09-22T19:50:10Z + +[Term] +id: GO:1904683 +name: regulation of metalloendopeptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] +synonym: "regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0052548 ! regulation of endopeptidase activity +is_a: GO:1905048 ! regulation of metallopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004222 ! metalloendopeptidase activity +relationship: regulates GO:0004222 ! metalloendopeptidase activity +created_by: rph +creation_date: 2015-09-24T11:18:14Z + +[Term] +id: GO:1904684 +name: negative regulation of metalloendopeptidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] +synonym: "down regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "down regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "downregulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendopeptidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of metalloendoprotease activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0010951 ! negative regulation of endopeptidase activity +is_a: GO:1904683 ! regulation of metalloendopeptidase activity +is_a: GO:1905049 ! negative regulation of metallopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004222 ! metalloendopeptidase activity +relationship: negatively_regulates GO:0004222 ! metalloendopeptidase activity +created_by: rph +creation_date: 2015-09-24T11:18:21Z + +[Term] +id: GO:1904685 +name: positive regulation of metalloendopeptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] +synonym: "activation of metalloendopeptidase activity" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "activation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloendoprotease activity" NARROW [GOC:TermGenie] +synonym: "upregulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0010950 ! positive regulation of endopeptidase activity +is_a: GO:1904683 ! regulation of metalloendopeptidase activity +is_a: GO:1905050 ! positive regulation of metallopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004222 ! metalloendopeptidase activity +relationship: positively_regulates GO:0004222 ! metalloendopeptidase activity +created_by: rph +creation_date: 2015-09-24T11:18:28Z + +[Term] +id: GO:1904686 +name: regulation of mitotic spindle disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic spindle disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:25963819] +synonym: "regulation of mitotic spindle breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic spindle catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic spindle degradation" EXACT [GOC:TermGenie] +synonym: "regulation of spindle breakdown during mitosis" EXACT [GOC:TermGenie] +synonym: "regulation of spindle degradation during mitosis" EXACT [GOC:TermGenie] +synonym: "regulation of spindle disassembly during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0060236 ! regulation of mitotic spindle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051228 ! mitotic spindle disassembly +relationship: regulates GO:0051228 ! mitotic spindle disassembly +created_by: al +creation_date: 2015-09-24T14:20:07Z + +[Term] +id: GO:1904687 +name: positive regulation of mitotic spindle disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:25963819] +synonym: "activation of mitotic spindle breakdown" NARROW [GOC:TermGenie] +synonym: "activation of mitotic spindle catabolism" NARROW [GOC:TermGenie] +synonym: "activation of mitotic spindle degradation" NARROW [GOC:TermGenie] +synonym: "activation of mitotic spindle disassembly" NARROW [GOC:TermGenie] +synonym: "activation of spindle breakdown during mitosis" NARROW [GOC:TermGenie] +synonym: "activation of spindle degradation during mitosis" NARROW [GOC:TermGenie] +synonym: "activation of spindle disassembly during mitosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitotic spindle breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic spindle catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic spindle degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of spindle breakdown during mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of spindle degradation during mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of spindle disassembly during mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic spindle breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic spindle catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic spindle degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic spindle disassembly" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle breakdown during mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle degradation during mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle disassembly during mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic spindle breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic spindle catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic spindle degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic spindle disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle breakdown during mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle degradation during mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle disassembly during mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic spindle breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic spindle catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic spindle degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic spindle disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle breakdown during mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle degradation during mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle disassembly during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0110028 ! positive regulation of mitotic spindle organization +is_a: GO:1904686 ! regulation of mitotic spindle disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051228 ! mitotic spindle disassembly +relationship: positively_regulates GO:0051228 ! mitotic spindle disassembly +created_by: al +creation_date: 2015-09-24T14:20:13Z + +[Term] +id: GO:1904688 +name: regulation of cytoplasmic translational initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] +is_a: GO:0006446 ! regulation of translational initiation +is_a: GO:2000765 ! regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002183 ! cytoplasmic translational initiation +relationship: regulates GO:0002183 ! cytoplasmic translational initiation +created_by: dos +creation_date: 2015-09-25T14:39:38Z + +[Term] +id: GO:1904689 +name: negative regulation of cytoplasmic translational initiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] +synonym: "down regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +synonym: "inhibition of cytoplasmic translational initiation" NARROW [GOC:TermGenie] +is_a: GO:0045947 ! negative regulation of translational initiation +is_a: GO:1904688 ! regulation of cytoplasmic translational initiation +is_a: GO:2000766 ! negative regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002183 ! cytoplasmic translational initiation +relationship: negatively_regulates GO:0002183 ! cytoplasmic translational initiation +created_by: dos +creation_date: 2015-09-25T14:39:44Z + +[Term] +id: GO:1904690 +name: positive regulation of cytoplasmic translational initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation." [GO_REF:0000058, GOC:TermGenie, PMID:12242291] +synonym: "activation of cytoplasmic translational initiation" NARROW [GOC:TermGenie] +synonym: "up regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cytoplasmic translational initiation" EXACT [GOC:TermGenie] +is_a: GO:0045948 ! positive regulation of translational initiation +is_a: GO:1904688 ! regulation of cytoplasmic translational initiation +is_a: GO:2000767 ! positive regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002183 ! cytoplasmic translational initiation +relationship: positively_regulates GO:0002183 ! cytoplasmic translational initiation +created_by: dos +creation_date: 2015-09-25T14:39:50Z + +[Term] +id: GO:1904691 +name: negative regulation of type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] +synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of pancreatic B cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation +relationship: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation +created_by: sl +creation_date: 2015-09-25T15:23:38Z + +[Term] +id: GO:1904692 +name: positive regulation of type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] +synonym: "activation of pancreatic B cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044342 ! type B pancreatic cell proliferation +relationship: positively_regulates GO:0044342 ! type B pancreatic cell proliferation +created_by: sl +creation_date: 2015-09-25T15:23:44Z + +[Term] +id: GO:1904693 +name: midbrain morphogenesis +namespace: biological_process +def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] +synonym: "MB morphogenesis" BROAD [GOC:TermGenie] +synonym: "mesencephalon morphogenesis" RELATED [GOC:TermGenie] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0030901 ! midbrain development +relationship: part_of GO:0048854 ! brain morphogenesis +created_by: bf +creation_date: 2015-09-29T09:15:28Z + +[Term] +id: GO:1904694 +name: negative regulation of vascular smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22158624] +synonym: "down regulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle contraction" NARROW [GOC:TermGenie] +is_a: GO:0003056 ! regulation of vascular smooth muscle contraction +is_a: GO:0045906 ! negative regulation of vasoconstriction +is_a: GO:0045986 ! negative regulation of smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014829 ! vascular smooth muscle contraction +relationship: negatively_regulates GO:0014829 ! vascular smooth muscle contraction +created_by: rph +creation_date: 2015-09-29T13:39:08Z + +[Term] +id: GO:1904695 +name: positive regulation of vascular smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22158624] +synonym: "activation of vascular smooth muscle contraction" NARROW [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle contraction" EXACT [GOC:TermGenie] +is_a: GO:0003056 ! regulation of vascular smooth muscle contraction +is_a: GO:0045907 ! positive regulation of vasoconstriction +is_a: GO:0045987 ! positive regulation of smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014829 ! vascular smooth muscle contraction +relationship: positively_regulates GO:0014829 ! vascular smooth muscle contraction +created_by: rph +creation_date: 2015-09-29T13:39:14Z + +[Term] +id: GO:1904697 +name: regulation of acinar cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] +synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990863 ! acinar cell proliferation +relationship: regulates GO:1990863 ! acinar cell proliferation +created_by: sl +creation_date: 2015-09-30T15:19:50Z + +[Term] +id: GO:1904698 +name: negative regulation of acinar cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] +synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of acinar cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of acinic cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of acinous cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:1904697 ! regulation of acinar cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990863 ! acinar cell proliferation +relationship: negatively_regulates GO:1990863 ! acinar cell proliferation +created_by: sl +creation_date: 2015-09-30T15:19:57Z + +[Term] +id: GO:1904699 +name: positive regulation of acinar cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] +synonym: "activation of acinar cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of acinic cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of acinous cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:1904697 ! regulation of acinar cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990863 ! acinar cell proliferation +relationship: positively_regulates GO:1990863 ! acinar cell proliferation +created_by: sl +creation_date: 2015-09-30T15:20:03Z + +[Term] +id: GO:1904700 +name: granulosa cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a granulosa cell." [GO_REF:0000085, GOC:TermGenie, PMID:19208546] +synonym: "granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2015-09-30T21:29:54Z + +[Term] +id: GO:1904701 +name: Wnt-Frizzled-LRP5/6 complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11448771] +synonym: "Frizzled-LRP5/6 complex assembly" RELATED [GOC:bf] +synonym: "Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "Wnt receptor complex assembly" BROAD [GOC:bf] +synonym: "WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2015-10-01T09:37:57Z + +[Term] +id: GO:1904702 +name: regulation of protein localization to adherens junction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:kmv, GOC:TermGenie, PMID:26412237] +synonym: "regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +is_a: GO:0150106 ! regulation of protein localization to cell-cell junction +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0071896 ! protein localization to adherens junction +relationship: regulates GO:0071896 ! protein localization to adherens junction +created_by: kmv +creation_date: 2015-10-01T15:11:49Z + +[Term] +id: GO:1904703 +name: negative regulation of protein localization to adherens junction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:kmv, GOC:TermGenie, PMID:26412237] +synonym: "down regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +is_a: GO:0150119 ! negative regulation of protein localization to cell-cell junction +is_a: GO:1904702 ! regulation of protein localization to adherens junction +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0071896 ! protein localization to adherens junction +relationship: negatively_regulates GO:0071896 ! protein localization to adherens junction +created_by: kmv +creation_date: 2015-10-01T15:11:56Z + +[Term] +id: GO:1904704 +name: positive regulation of protein localization to adherens junction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:kmv, GOC:TermGenie, PMID:26412237] +synonym: "activation of protein localisation in cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to cell-cell adherens junction" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in cell-cell adherens junction" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cell-cell adherens junction" EXACT [GOC:TermGenie] +is_a: GO:0150107 ! positive regulation of protein localization to cell-cell junction +is_a: GO:1904702 ! regulation of protein localization to adherens junction +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0071896 ! protein localization to adherens junction +relationship: positively_regulates GO:0071896 ! protein localization to adherens junction +created_by: kmv +creation_date: 2015-10-01T15:12:02Z + +[Term] +id: GO:1904705 +name: regulation of vascular smooth muscle cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] +synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048660 ! regulation of smooth muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990874 ! vascular smooth muscle cell proliferation +relationship: regulates GO:1990874 ! vascular smooth muscle cell proliferation +created_by: sl +creation_date: 2015-10-01T16:05:20Z + +[Term] +id: GO:1904706 +name: negative regulation of vascular smooth muscle cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] +synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of VSMC proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation +is_a: GO:1904705 ! regulation of vascular smooth muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990874 ! vascular smooth muscle cell proliferation +relationship: negatively_regulates GO:1990874 ! vascular smooth muscle cell proliferation +created_by: sl +creation_date: 2015-10-01T16:05:26Z + +[Term] +id: GO:1904707 +name: positive regulation of vascular smooth muscle cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] +synonym: "activation of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of VSMC proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation +is_a: GO:1904705 ! regulation of vascular smooth muscle cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990874 ! vascular smooth muscle cell proliferation +relationship: positively_regulates GO:1990874 ! vascular smooth muscle cell proliferation +created_by: sl +creation_date: 2015-10-01T16:05:32Z + +[Term] +id: GO:1904708 +name: regulation of granulosa cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19208546] +synonym: "regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904700 ! granulosa cell apoptotic process +relationship: regulates GO:1904700 ! granulosa cell apoptotic process +created_by: sl +creation_date: 2015-10-01T16:09:38Z + +[Term] +id: GO:1904709 +name: negative regulation of granulosa cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19208546] +synonym: "down regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of granulosa cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of granulosa cell of ovary apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:1904708 ! regulation of granulosa cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904700 ! granulosa cell apoptotic process +relationship: negatively_regulates GO:1904700 ! granulosa cell apoptotic process +created_by: sl +creation_date: 2015-10-01T16:09:45Z + +[Term] +id: GO:1904710 +name: positive regulation of granulosa cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19208546] +synonym: "activation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of granulosa cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of granulosa cell of ovary apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of granulosa cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of granulosa cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of granulosa cell of ovary apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of granulosa cell of ovary apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:1904708 ! regulation of granulosa cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904700 ! granulosa cell apoptotic process +relationship: positively_regulates GO:1904700 ! granulosa cell apoptotic process +created_by: sl +creation_date: 2015-10-01T16:09:51Z + +[Term] +id: GO:1904711 +name: regulation of Wnt-Frizzled-LRP5/6 complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of Frizzled-LRP5/6 complex assembly" RELATED [GOC:bf] +synonym: "regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt receptor complex assembly" BROAD [GOC:TermGenie] +synonym: "regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +relationship: regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +created_by: bf +creation_date: 2015-10-05T14:02:22Z + +[Term] +id: GO:1904712 +name: positive regulation of Wnt-Frizzled-LRP5/6 complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of Frizzled-LRP5/6 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "activation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt-FZD-LRP5/6 trimeric complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Wnt-FZD-LRP5/6 trimeric complex formation" NARROW [GOC:TermGenie] +synonym: "activation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of Frizzled-LRP5/6 complex assembly" RELATED [GOC:bf] +synonym: "positive regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "up regulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "up regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "up regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "up regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "upregulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "upregulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "upregulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "upregulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1904711 ! regulation of Wnt-Frizzled-LRP5/6 complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +relationship: positively_regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +created_by: bf +creation_date: 2015-10-05T14:02:35Z + +[Term] +id: GO:1904713 +name: beta-catenin destruction complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a beta-catenin destruction complex." [GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22899650] +synonym: "23S APC complex binding" NARROW [GOC:TermGenie] +synonym: "APC-Axin-1-beta-catenin complex binding" EXACT [GOC:TermGenie] +synonym: "Axin-APC-beta-catenin-GSK3B complex binding" EXACT [GOC:TermGenie] +synonym: "BDC binding" EXACT [PMID:22899650] +synonym: "beta-catenin degradation complex binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bf +creation_date: 2015-10-05T14:34:14Z + +[Term] +id: GO:1904714 +name: regulation of chaperone-mediated autophagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20176123] +synonym: "regulation of CMA" RELATED [GOC:TermGenie] +is_a: GO:0010506 ! regulation of autophagy +is_a: GO:0042176 ! regulation of protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061684 ! chaperone-mediated autophagy +relationship: regulates GO:0061684 ! chaperone-mediated autophagy +created_by: pad +creation_date: 2015-10-06T08:49:02Z + +[Term] +id: GO:1904715 +name: negative regulation of chaperone-mediated autophagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20176123] +synonym: "down regulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "down regulation of CMA" RELATED [GOC:TermGenie] +synonym: "down-regulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of CMA" RELATED [GOC:TermGenie] +synonym: "downregulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "downregulation of CMA" RELATED [GOC:TermGenie] +synonym: "inhibition of chaperone-mediated autophagy" NARROW [GOC:TermGenie] +synonym: "inhibition of CMA" RELATED [GOC:TermGenie] +synonym: "negative regulation of CMA" RELATED [GOC:TermGenie] +is_a: GO:0010507 ! negative regulation of autophagy +is_a: GO:0042177 ! negative regulation of protein catabolic process +is_a: GO:1904714 ! regulation of chaperone-mediated autophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061684 ! chaperone-mediated autophagy +relationship: negatively_regulates GO:0061684 ! chaperone-mediated autophagy +created_by: pad +creation_date: 2015-10-06T08:49:09Z + +[Term] +id: GO:1904716 +name: positive regulation of chaperone-mediated autophagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20176123] +synonym: "activation of chaperone-mediated autophagy" NARROW [GOC:TermGenie] +synonym: "activation of CMA" RELATED [GOC:TermGenie] +synonym: "positive regulation of CMA" RELATED [GOC:TermGenie] +synonym: "up regulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "up regulation of CMA" RELATED [GOC:TermGenie] +synonym: "up-regulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of CMA" RELATED [GOC:TermGenie] +synonym: "upregulation of chaperone-mediated autophagy" EXACT [GOC:TermGenie] +synonym: "upregulation of CMA" RELATED [GOC:TermGenie] +is_a: GO:0010508 ! positive regulation of autophagy +is_a: GO:0045732 ! positive regulation of protein catabolic process +is_a: GO:1904714 ! regulation of chaperone-mediated autophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061684 ! chaperone-mediated autophagy +relationship: positively_regulates GO:0061684 ! chaperone-mediated autophagy +created_by: pad +creation_date: 2015-10-06T08:49:15Z + +[Term] +id: GO:1904717 +name: regulation of AMPA glutamate receptor clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:21558424] +synonym: "regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:0106104 ! regulation of glutamate receptor clustering +is_a: GO:1901626 ! regulation of postsynaptic membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097113 ! AMPA glutamate receptor clustering +relationship: regulates GO:0097113 ! AMPA glutamate receptor clustering +created_by: hjd +creation_date: 2015-10-07T19:32:11Z + +[Term] +id: GO:1904718 +name: negative regulation of AMPA glutamate receptor clustering +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:21558424] +synonym: "down regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "down regulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "down regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "down-regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "downregulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "inhibition of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" NARROW [GOC:TermGenie] +synonym: "inhibition of AMPA glutamate receptor clustering" NARROW [GOC:TermGenie] +synonym: "inhibition of AMPA receptor clustering" NARROW [GOC:TermGenie] +synonym: "negative regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "negative regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1901627 ! negative regulation of postsynaptic membrane organization +is_a: GO:1903910 ! negative regulation of receptor clustering +is_a: GO:1904717 ! regulation of AMPA glutamate receptor clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097113 ! AMPA glutamate receptor clustering +relationship: negatively_regulates GO:0097113 ! AMPA glutamate receptor clustering +created_by: hjd +creation_date: 2015-10-07T19:32:28Z + +[Term] +id: GO:1904719 +name: positive regulation of AMPA glutamate receptor clustering +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:21558424] +synonym: "activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" NARROW [GOC:TermGenie] +synonym: "activation of AMPA glutamate receptor clustering" NARROW [GOC:TermGenie] +synonym: "activation of AMPA receptor clustering" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "positive regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "up regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "up-regulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of AMPA glutamate receptor clustering" EXACT [GOC:TermGenie] +synonym: "upregulation of AMPA receptor clustering" EXACT [GOC:TermGenie] +is_a: GO:1901628 ! positive regulation of postsynaptic membrane organization +is_a: GO:1903911 ! positive regulation of receptor clustering +is_a: GO:1904717 ! regulation of AMPA glutamate receptor clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097113 ! AMPA glutamate receptor clustering +relationship: positively_regulates GO:0097113 ! AMPA glutamate receptor clustering +created_by: hjd +creation_date: 2015-10-07T19:32:34Z + +[Term] +id: GO:1904720 +name: obsolete regulation of mRNA endonucleolytic cleavage involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19328063, PMID:20625543] +comment: The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted. +synonym: "regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:1903895 +created_by: bf +creation_date: 2015-10-08T14:52:49Z + +[Term] +id: GO:1904721 +name: obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19328063] +comment: The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted. +synonym: "down regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "down regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "down regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "down regulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "down-regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "down-regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "down-regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "down-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "down-regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "downregulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "downregulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "downregulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "downregulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "downregulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "inhibition of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "inhibition of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "inhibition of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "inhibition of mRNA endonucleolytic cleavage involved in unfolded protein response" NARROW [GOC:TermGenie] +synonym: "inhibition of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "negative regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "negative regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "negative regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "negative regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:1903895 +created_by: bf +creation_date: 2015-10-08T14:52:55Z + +[Term] +id: GO:1904722 +name: obsolete positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:20625543] +comment: The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted. +synonym: "activation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "activation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "activation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "activation of mRNA endonucleolytic cleavage involved in unfolded protein response" NARROW [GOC:TermGenie] +synonym: "activation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "positive regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "positive regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "positive regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "positive regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "up regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up regulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up-regulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up-regulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "up-regulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "up-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "up-regulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "upregulation of HAC1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "upregulation of HAC1-type intron splice site recognition and cleavage" NARROW [GOC:TermGenie] +synonym: "upregulation of IRE1-mediated XBP-1 mRNA cleavage" NARROW [GOC:TermGenie] +synonym: "upregulation of mRNA endonucleolytic cleavage involved in unfolded protein response" EXACT [GOC:TermGenie] +synonym: "upregulation of XBP1 mRNA cleavage" NARROW [GOC:TermGenie] +is_obsolete: true +consider: GO:1903896 +created_by: bf +creation_date: 2015-10-08T14:53:02Z + +[Term] +id: GO:1904723 +name: negative regulation of Wnt-Frizzled-LRP5/6 complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11433302] +synonym: "down regulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "down regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "downregulation of Frizzled-LRP5/6 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "downregulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "inhibition of Frizzled-LRP5/6 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "inhibition of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt-FZD-LRP5/6 trimeric complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of Frizzled-LRP5/6 complex assembly" RELATED [GOC:bf] +synonym: "negative regulation of Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of WNT-FZD-LRP5 complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of WNT-FZD-LRP5 complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of WNT-FZD-LRP6 complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of WNT-FZD-LRP6 complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1904711 ! regulation of Wnt-Frizzled-LRP5/6 complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +relationship: negatively_regulates GO:1904701 ! Wnt-Frizzled-LRP5/6 complex assembly +created_by: bf +creation_date: 2015-10-12T08:14:59Z + +[Term] +id: GO:1904724 +name: tertiary granule lumen +namespace: cellular_component +def: "Any membrane-enclosed lumen that is part of a tertiary granule." [GO_REF:0000064, GOC:TermGenie, PMID:23650620] +synonym: "gelatinase granule membrane-enclosed lumen" RELATED [] +synonym: "membrane-enclosed lumen of gelatinase granule" EXACT [GOC:TermGenie] +synonym: "membrane-enclosed lumen of tertiary granule" EXACT [GOC:TermGenie] +synonym: "tertiary granule membrane-enclosed lumen" EXACT [] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0070820 ! tertiary granule +relationship: part_of GO:0070820 ! tertiary granule +created_by: mec +creation_date: 2015-10-12T12:53:10Z + +[Term] +id: GO:1904725 +name: obsolete TFIIB-class transcription factor binding involved in negative regulation of transcription +namespace: molecular_function +def: "OBSOLETE. Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription." [GO_REF:0000061, GOC:rb, GOC:TermGenie, PMID:12461786] +comment: The reason for obsoletion is that this term represents a GO-CAM model. +synonym: "TFIIB-class transcription factor binding involved in down regulation of gene-specific transcription" RELATED [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in down regulation of transcription, DNA-dependent" EXACT [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in down-regulation of gene-specific transcription" RELATED [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in down-regulation of transcription, DNA-dependent" EXACT [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in downregulation of gene-specific transcription" RELATED [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in downregulation of transcription, DNA-dependent" EXACT [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in inhibition of gene-specific transcription" RELATED [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in inhibition of transcription, DNA-dependent" NARROW [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in negative regulation of cellular transcription, DNA-dependent" EXACT [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in negative regulation of gene-specific transcription" RELATED [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-dependent" EXACT [GOC:TermGenie] +synonym: "TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-templated" EXACT [] +synonym: "TFIIB-class transcription factor binding involved in transcription repressor activity" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: tb +creation_date: 2015-10-13T19:49:39Z + +[Term] +id: GO:1904726 +name: regulation of replicative senescence +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of replicative senescence." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23496142] +is_a: GO:0090342 ! regulation of cell aging +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090399 ! replicative senescence +relationship: regulates GO:0090399 ! replicative senescence +created_by: rph +creation_date: 2015-10-14T13:11:24Z + +[Term] +id: GO:1904727 +name: negative regulation of replicative senescence +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23496142] +synonym: "down regulation of replicative senescence" EXACT [GOC:TermGenie] +synonym: "down-regulation of replicative senescence" EXACT [GOC:TermGenie] +synonym: "downregulation of replicative senescence" EXACT [GOC:TermGenie] +synonym: "inhibition of replicative senescence" NARROW [GOC:TermGenie] +is_a: GO:0090344 ! negative regulation of cell aging +is_a: GO:1904726 ! regulation of replicative senescence +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090399 ! replicative senescence +relationship: negatively_regulates GO:0090399 ! replicative senescence +created_by: rph +creation_date: 2015-10-14T13:11:31Z + +[Term] +id: GO:1904728 +name: positive regulation of replicative senescence +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of replicative senescence." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23496142] +synonym: "activation of replicative senescence" NARROW [GOC:TermGenie] +synonym: "up regulation of replicative senescence" EXACT [GOC:TermGenie] +synonym: "up-regulation of replicative senescence" EXACT [GOC:TermGenie] +synonym: "upregulation of replicative senescence" EXACT [GOC:TermGenie] +is_a: GO:0090343 ! positive regulation of cell aging +is_a: GO:1904726 ! regulation of replicative senescence +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090399 ! replicative senescence +relationship: positively_regulates GO:0090399 ! replicative senescence +created_by: rph +creation_date: 2015-10-14T13:11:37Z + +[Term] +id: GO:1904729 +name: regulation of intestinal lipid absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intestinal lipid absorption." [GO_REF:0000058, GOC:TermGenie, PMID:18768481] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:1904478 ! regulation of intestinal absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098856 ! intestinal lipid absorption +relationship: regulates GO:0098856 ! intestinal lipid absorption +created_by: sl +creation_date: 2015-10-14T15:24:56Z + +[Term] +id: GO:1904730 +name: negative regulation of intestinal lipid absorption +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption." [GO_REF:0000058, GOC:TermGenie, PMID:18768481] +synonym: "down regulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +synonym: "down-regulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +synonym: "downregulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +synonym: "inhibition of intestinal lipid absorption" NARROW [GOC:TermGenie] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:1904479 ! negative regulation of intestinal absorption +is_a: GO:1904729 ! regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098856 ! intestinal lipid absorption +relationship: negatively_regulates GO:0098856 ! intestinal lipid absorption +created_by: sl +creation_date: 2015-10-14T15:25:03Z + +[Term] +id: GO:1904731 +name: positive regulation of intestinal lipid absorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption." [GO_REF:0000058, GOC:TermGenie, PMID:18768481] +synonym: "activation of intestinal lipid absorption" NARROW [GOC:TermGenie] +synonym: "up regulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +synonym: "up-regulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +synonym: "upregulation of intestinal lipid absorption" EXACT [GOC:TermGenie] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:1904480 ! positive regulation of intestinal absorption +is_a: GO:1904729 ! regulation of intestinal lipid absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098856 ! intestinal lipid absorption +relationship: positively_regulates GO:0098856 ! intestinal lipid absorption +created_by: sl +creation_date: 2015-10-14T15:25:10Z + +[Term] +id: GO:1904732 +name: regulation of electron transfer activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of electron transfer activity." [GO_REF:0000059, GOC:TermGenie, PMID:25416781] +synonym: "regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "regulation of azurin" NARROW [GOC:TermGenie] +synonym: "regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "regulation of electron transporter activity" EXACT [GOC:TermGenie] +synonym: "regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009055 ! electron transfer activity +relationship: regulates GO:0009055 ! electron transfer activity +created_by: lb +creation_date: 2015-10-15T07:51:19Z + +[Term] +id: GO:1904733 +name: negative regulation of electron transfer activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity." [GO_REF:0000059, GOC:TermGenie, PMID:25416781] +synonym: "down regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "down regulation of azurin" NARROW [GOC:TermGenie] +synonym: "down regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "down regulation of electron carrier activity" EXACT [GOC:TermGenie] +synonym: "down regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "down regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "down regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "down regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "down regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "down regulation of electron transporter activity" EXACT [GOC:TermGenie] +synonym: "down regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "down regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "down regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "down-regulation of azurin" NARROW [GOC:TermGenie] +synonym: "down-regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron carrier activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "down-regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "down-regulation of electron transporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "down-regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "down-regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "downregulation of azurin" NARROW [GOC:TermGenie] +synonym: "downregulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "downregulation of electron carrier activity" EXACT [GOC:TermGenie] +synonym: "downregulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "downregulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "downregulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "downregulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "downregulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "downregulation of electron transporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "downregulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "downregulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of amicyanin" NARROW [GOC:TermGenie] +synonym: "inhibition of azurin" NARROW [GOC:TermGenie] +synonym: "inhibition of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of electron carrier activity" NARROW [GOC:TermGenie] +synonym: "inhibition of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "inhibition of electron donor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "inhibition of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "inhibition of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "inhibition of electron transporter activity" NARROW [GOC:TermGenie] +synonym: "inhibition of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of rubredoxin" NARROW [GOC:TermGenie] +synonym: "inhibition of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "inhibition of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "negative regulation of azurin" NARROW [GOC:TermGenie] +synonym: "negative regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "negative regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "negative regulation of electron transporter activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "negative regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:1904732 ! regulation of electron transfer activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009055 ! electron transfer activity +relationship: negatively_regulates GO:0009055 ! electron transfer activity +created_by: lb +creation_date: 2015-10-15T07:51:26Z + +[Term] +id: GO:1904734 +name: positive regulation of electron transfer activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of electron transfer activity." [GO_REF:0000059, GOC:TermGenie, PMID:25416781] +synonym: "activation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "activation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "activation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of amicyanin" NARROW [GOC:TermGenie] +synonym: "activation of azurin" NARROW [GOC:TermGenie] +synonym: "activation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "activation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "activation of electron carrier activity" NARROW [GOC:TermGenie] +synonym: "activation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "activation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "activation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "activation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "activation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "activation of electron transporter activity" NARROW [GOC:TermGenie] +synonym: "activation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "activation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "activation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "activation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "activation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "activation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "activation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "activation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "positive regulation of azurin" NARROW [GOC:TermGenie] +synonym: "positive regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "positive regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "positive regulation of electron transporter activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "positive regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "up regulation of azurin" NARROW [GOC:TermGenie] +synonym: "up regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "up regulation of electron carrier activity" RELATED [GOC:TermGenie] +synonym: "up regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "up regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "up regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "up regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "up regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "up regulation of electron transporter activity" RELATED [GOC:TermGenie] +synonym: "up regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "up regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "up regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "up-regulation of azurin" NARROW [GOC:TermGenie] +synonym: "up-regulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron carrier activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "up-regulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "up-regulation of electron transporter activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "up-regulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "up-regulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of 2Fe-2S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of 3Fe-4S/4Fe-4S electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of adrenodoxin-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of amicyanin" NARROW [GOC:TermGenie] +synonym: "upregulation of azurin" NARROW [GOC:TermGenie] +synonym: "upregulation of bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of chloroplast-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of copper electron carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of dicluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of electron acceptor activity" NARROW [GOC:TermGenie] +synonym: "upregulation of electron carrier activity" RELATED [GOC:TermGenie] +synonym: "upregulation of electron carrier, chlorophyll electron transport system" RELATED [GOC:TermGenie] +synonym: "upregulation of electron donor activity" NARROW [GOC:TermGenie] +synonym: "upregulation of electron transfer flavoprotein" NARROW [GOC:TermGenie] +synonym: "upregulation of electron transfer flavoprotein, group I" NARROW [GOC:TermGenie] +synonym: "upregulation of electron transfer flavoprotein, group II" NARROW [GOC:TermGenie] +synonym: "upregulation of electron transporter activity" RELATED [GOC:TermGenie] +synonym: "upregulation of high-potential iron-sulfur carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of iron-sulfur electron transfer carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of monocluster bacterial-type ferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of mononuclear iron electron carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of polyferredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of redox-active disulfide bond electron carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of rubredoxin" NARROW [GOC:TermGenie] +synonym: "upregulation of small blue copper electron carrier" NARROW [GOC:TermGenie] +synonym: "upregulation of thioredoxin-like 2Fe-2S ferredoxin" NARROW [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1904732 ! regulation of electron transfer activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009055 ! electron transfer activity +relationship: positively_regulates GO:0009055 ! electron transfer activity +created_by: lb +creation_date: 2015-10-15T07:51:32Z + +[Term] +id: GO:1904735 +name: regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase." [GO_REF:0000058, GOC:TermGenie, PMID:25416781] +is_a: GO:0031998 ! regulation of fatty acid beta-oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +relationship: regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +created_by: lb +creation_date: 2015-10-15T08:14:51Z + +[Term] +id: GO:1904736 +name: negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase." [GO_REF:0000058, GOC:TermGenie, PMID:25416781] +synonym: "down regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +synonym: "down-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +synonym: "downregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +synonym: "inhibition of fatty acid beta-oxidation using acyl-CoA dehydrogenase" NARROW [GOC:TermGenie] +is_a: GO:0031999 ! negative regulation of fatty acid beta-oxidation +is_a: GO:1904735 ! regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +relationship: negatively_regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +created_by: lb +creation_date: 2015-10-15T08:14:57Z + +[Term] +id: GO:1904737 +name: positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase." [GO_REF:0000058, GOC:TermGenie, PMID:25416781] +synonym: "activation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" NARROW [GOC:TermGenie] +synonym: "up regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +synonym: "up-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +synonym: "upregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase" EXACT [GOC:TermGenie] +is_a: GO:0032000 ! positive regulation of fatty acid beta-oxidation +is_a: GO:1904735 ! regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +relationship: positively_regulates GO:0033539 ! fatty acid beta-oxidation using acyl-CoA dehydrogenase +created_by: lb +creation_date: 2015-10-15T08:15:03Z + +[Term] +id: GO:1904738 +name: vascular associated smooth muscle cell migration +namespace: biological_process +def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] +synonym: "vascular smooth muscle cell migration" EXACT [] +is_a: GO:0014909 ! smooth muscle cell migration +created_by: rph +creation_date: 2015-10-15T09:56:00Z + +[Term] +id: GO:1904739 +name: regulation of synapse organization by posttranscriptional regulation of gene expression +namespace: biological_process +def: "A posttranscriptional regulation of gene expression that results in regulation of synapse organization." [GO_REF:0000063, GOC:rb, GOC:TermGenie, PMID:20729808] +synonym: "regulation of synapse development by posttranscriptional regulation of gene expression" EXACT [GOC:TermGenie] +synonym: "regulation of synapse morphogenesis by posttranscriptional regulation of gene expression" RELATED [GOC:TermGenie] +synonym: "regulation of synapse organisation by posttranscriptional regulation of gene expression" EXACT [GOC:TermGenie] +synonym: "regulation of synapse organization and biogenesis by posttranscriptional regulation of gene expression" RELATED [GOC:TermGenie] +is_a: GO:0010608 ! posttranscriptional regulation of gene expression +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0010608 ! posttranscriptional regulation of gene expression +intersection_of: regulates GO:0050808 ! synapse organization +created_by: tb +creation_date: 2015-10-15T21:25:46Z + +[Term] +id: GO:1904740 +name: obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation." [GO_REF:0000063, GOC:rn, GOC:TermGenie, PMID:26448198] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by general transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by RNA polymerase II transcription factor activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from Pol II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: tb +creation_date: 2015-10-15T21:30:51Z + +[Term] +id: GO:1904741 +name: obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation." [GO_REF:0000063, GOC:rn, GOC:TermGenie, PMID:26448198] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of global transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of global transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: tb +creation_date: 2015-10-15T21:40:43Z + +[Term] +id: GO:1904742 +name: regulation of telomeric DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042162 ! telomeric DNA binding +relationship: regulates GO:0042162 ! telomeric DNA binding +created_by: nc +creation_date: 2015-10-19T12:18:48Z + +[Term] +id: GO:1904743 +name: negative regulation of telomeric DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "down regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "downregulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "inhibition of telomere binding" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric repeat binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:1904742 ! regulation of telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042162 ! telomeric DNA binding +relationship: negatively_regulates GO:0042162 ! telomeric DNA binding +created_by: nc +creation_date: 2015-10-19T12:18:55Z + +[Term] +id: GO:1904744 +name: positive regulation of telomeric DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "activation of telomere binding" NARROW [GOC:TermGenie] +synonym: "activation of telomeric DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of telomeric repeat binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "up regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric repeat binding" EXACT [GOC:TermGenie] +synonym: "upregulation of telomere binding" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric repeat binding" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:1904742 ! regulation of telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042162 ! telomeric DNA binding +relationship: positively_regulates GO:0042162 ! telomeric DNA binding +created_by: nc +creation_date: 2015-10-19T12:19:01Z + +[Term] +id: GO:1904745 +name: Atg1/ULK1 kinase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex." [GO_REF:0000079, GOC:dph, GOC:TermGenie, PMID:25139988] +synonym: "ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: dph +creation_date: 2015-10-19T12:33:08Z + +[Term] +id: GO:1904746 +name: negative regulation of apoptotic process involved in development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] +comment: U4PR86 in PMID:22801495 inferred from mutant phenotype +synonym: "down regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "down-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "down-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "downregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "downregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "downregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "downregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "downregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "downregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "downregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "downregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "downregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "downregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "downregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "downregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "inhibition of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "inhibition of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "inhibition of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "inhibition of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "inhibition of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "inhibition of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "inhibition of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "inhibition of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "inhibition of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "inhibition of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "negative regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "negative regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "negative regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "negative regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "negative regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "negative regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "negative regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "negative regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "negative regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "negative regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902742 ! apoptotic process involved in development +relationship: negatively_regulates GO:1902742 ! apoptotic process involved in development +created_by: es +creation_date: 2015-10-19T14:12:27Z + +[Term] +id: GO:1904747 +name: positive regulation of apoptotic process involved in development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] +comment: U4PR86 in PMID:22801495 inferred from mutant phenotype +synonym: "activation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "activation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process involved in development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "activation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "activation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "activation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "activation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "activation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "activation of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "activation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "activation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "activation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "activation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "positive regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "positive regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "positive regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "positive regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "positive regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "positive regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "positive regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "up-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "up-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "upregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "upregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "upregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "upregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "upregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "upregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "upregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "upregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "upregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "upregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "upregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "upregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1904748 ! regulation of apoptotic process involved in development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902742 ! apoptotic process involved in development +relationship: positively_regulates GO:1902742 ! apoptotic process involved in development +created_by: es +creation_date: 2015-10-19T14:12:34Z + +[Term] +id: GO:1904748 +name: regulation of apoptotic process involved in development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] +comment: Q10943 in PMID:22801495, inferred from mutant phenotype +synonym: "regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] +synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] +synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] +synonym: "regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] +synonym: "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] +synonym: "regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] +synonym: "regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] +is_a: GO:0042981 ! regulation of apoptotic process +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902742 ! apoptotic process involved in development +relationship: regulates GO:1902742 ! apoptotic process involved in development +created_by: es +creation_date: 2015-10-19T15:02:28Z + +[Term] +id: GO:1904749 +name: regulation of protein localization to nucleolus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +is_a: GO:1900180 ! regulation of protein localization to nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902570 ! protein localization to nucleolus +relationship: regulates GO:1902570 ! protein localization to nucleolus +created_by: nc +creation_date: 2015-10-19T15:16:17Z + +[Term] +id: GO:1904750 +name: negative regulation of protein localization to nucleolus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in nucleolus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to nucleolus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in nucleolus" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to nucleolus" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +is_a: GO:1900181 ! negative regulation of protein localization to nucleus +is_a: GO:1904749 ! regulation of protein localization to nucleolus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902570 ! protein localization to nucleolus +relationship: negatively_regulates GO:1902570 ! protein localization to nucleolus +created_by: nc +creation_date: 2015-10-19T15:16:24Z + +[Term] +id: GO:1904751 +name: positive regulation of protein localization to nucleolus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] +synonym: "activation of protein localisation in nucleolus" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to nucleolus" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in nucleolus" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to nucleolus" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] +is_a: GO:1900182 ! positive regulation of protein localization to nucleus +is_a: GO:1904749 ! regulation of protein localization to nucleolus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902570 ! protein localization to nucleolus +relationship: positively_regulates GO:1902570 ! protein localization to nucleolus +created_by: nc +creation_date: 2015-10-19T15:16:30Z + +[Term] +id: GO:1904752 +name: regulation of vascular associated smooth muscle cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] +synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014910 ! regulation of smooth muscle cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904738 ! vascular associated smooth muscle cell migration +relationship: regulates GO:1904738 ! vascular associated smooth muscle cell migration +created_by: rph +creation_date: 2015-10-19T15:49:52Z + +[Term] +id: GO:1904753 +name: negative regulation of vascular associated smooth muscle cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] +synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014912 ! negative regulation of smooth muscle cell migration +is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration +relationship: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration +created_by: rph +creation_date: 2015-10-19T15:49:58Z + +[Term] +id: GO:1904754 +name: positive regulation of vascular associated smooth muscle cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] +synonym: "activation of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] +is_a: GO:0014911 ! positive regulation of smooth muscle cell migration +is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration +relationship: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration +created_by: rph +creation_date: 2015-10-19T15:50:05Z + +[Term] +id: GO:1904755 +name: regulation of gut granule assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gut granule assembly." [GO_REF:0000058, GOC:TermGenie, PMID:17535251] +synonym: "regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of gut granule formation" EXACT [GOC:TermGenie] +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902900 ! gut granule assembly +relationship: regulates GO:1902900 ! gut granule assembly +created_by: ah +creation_date: 2015-10-21T08:43:44Z + +[Term] +id: GO:1904756 +name: negative regulation of gut granule assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly." [GO_REF:0000058, GOC:TermGenie, PMID:17535251] +synonym: "down regulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "downregulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "inhibition of gut granule assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of gut granule biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of gut granule formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of gut granule formation" EXACT [GOC:TermGenie] +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:1904755 ! regulation of gut granule assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902900 ! gut granule assembly +relationship: negatively_regulates GO:1902900 ! gut granule assembly +created_by: ah +creation_date: 2015-10-21T08:43:51Z + +[Term] +id: GO:1904757 +name: positive regulation of gut granule assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gut granule assembly." [GO_REF:0000058, GOC:TermGenie, PMID:17535251] +synonym: "activation of gut granule assembly" NARROW [GOC:TermGenie] +synonym: "activation of gut granule biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of gut granule formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "up regulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gut granule formation" EXACT [GOC:TermGenie] +synonym: "upregulation of gut granule assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of gut granule biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gut granule formation" EXACT [GOC:TermGenie] +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:1904755 ! regulation of gut granule assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902900 ! gut granule assembly +relationship: positively_regulates GO:1902900 ! gut granule assembly +created_by: ah +creation_date: 2015-10-21T08:43:57Z + +[Term] +id: GO:1904758 +name: protein localization to new growing cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a new growing cell tip." [GO_REF:0000087, GOC:TermGenie, PMID:19431238] +synonym: "protein localisation in new growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localisation to new growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization in new growing cell tip" EXACT [GOC:TermGenie] +synonym: "protein localization to new cell tip after activation of bipolar cell growth" EXACT [] +synonym: "protein localization to new growing cell end" EXACT [] +synonym: "protein localization to post-NETO new cell end" EXACT [] +synonym: "protein localization to post-NETO new cell tip" EXACT [] +synonym: "protein localization to post-new end take-off new cell tip" EXACT [] +is_a: GO:1902486 ! protein localization to growing cell tip +created_by: mah +creation_date: 2015-10-21T12:37:48Z + +[Term] +id: GO:1904759 +name: protein localization to equatorial microtubule organizing center +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center." [GO_REF:0000087, GOC:TermGenie, PMID:16611237] +synonym: "protein localisation in equatorial microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localisation to equatorial microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localization in equatorial microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localization to eMTOC" EXACT [] +is_a: GO:0072741 ! protein localization to cell division site +is_a: GO:1905508 ! protein localization to microtubule organizing center +created_by: mah +creation_date: 2015-10-21T12:37:55Z + +[Term] +id: GO:1904760 +name: regulation of myofibroblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myofibroblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20533548] +synonym: "regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036446 ! myofibroblast differentiation +relationship: regulates GO:0036446 ! myofibroblast differentiation +created_by: rph +creation_date: 2015-10-23T12:15:05Z + +[Term] +id: GO:1904761 +name: negative regulation of myofibroblast differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20533548] +synonym: "down regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of myofibroblast cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of myofibroblast differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1904760 ! regulation of myofibroblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036446 ! myofibroblast differentiation +relationship: negatively_regulates GO:0036446 ! myofibroblast differentiation +created_by: rph +creation_date: 2015-10-23T12:15:11Z + +[Term] +id: GO:1904762 +name: positive regulation of myofibroblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20533548] +synonym: "activation of myofibroblast cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of myofibroblast differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of myofibroblast cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of myofibroblast differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1904760 ! regulation of myofibroblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036446 ! myofibroblast differentiation +relationship: positively_regulates GO:0036446 ! myofibroblast differentiation +created_by: rph +creation_date: 2015-10-23T12:15:17Z + +[Term] +id: GO:1904763 +name: chaperone-mediated autophagy translocation complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:18644871] +synonym: "chaperone-mediated autophagy receptor complex assembly" RELATED [GOC:TermGenie] +synonym: "chaperone-mediated autophagy receptor complex formation" RELATED [GOC:TermGenie] +synonym: "chaperone-mediated autophagy translocation complex formation" EXACT [GOC:TermGenie] +synonym: "CMA receptor complex assembly" RELATED [GOC:TermGenie] +synonym: "CMA receptor complex formation" RELATED [GOC:TermGenie] +synonym: "CMA translocation complex assembly" EXACT [GOC:TermGenie] +synonym: "CMA translocation complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +relationship: part_of GO:0061684 ! chaperone-mediated autophagy +created_by: pad +creation_date: 2015-10-26T16:34:29Z + +[Term] +id: GO:1904764 +name: chaperone-mediated autophagy translocation complex disassembly +namespace: biological_process +def: "The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:18644871] +synonym: "chaperone-mediated autophagy receptor complex disassembly" RELATED [GOC:TermGenie] +synonym: "CMA receptor complex disassembly" RELATED [GOC:TermGenie] +synonym: "CMA translocation complex disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: pad +creation_date: 2015-10-26T16:34:36Z + +[Term] +id: GO:1904765 +name: positive regulation of transcription from RNA polymerase II promoter in response to maltose +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus." [GO_REF:0000060, GOC:TermGenie, PMID:24224056] +synonym: "activation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "activation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "positive regulation of global transcription from Pol II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "positive regulation of transcription from Pol II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "stimulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" NARROW [GOC:TermGenie] +synonym: "stimulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "up regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "up-regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" RELATED [GOC:TermGenie] +synonym: "upregulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus" EXACT [GOC:TermGenie] +is_a: GO:1901522 ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0071328 ! cellular response to maltose stimulus +relationship: part_of GO:0071328 ! cellular response to maltose stimulus +created_by: mah +creation_date: 2015-10-26T16:42:15Z + +[Term] +id: GO:1904766 +name: negative regulation of macroautophagy by TORC1 signaling +namespace: biological_process +def: "A TORC1 signaling that results in negative regulation of macroautophagy." [GO_REF:0000063, GOC:autophagy, GOC:dph, GOC:TermGenie, PMID:23602450] +synonym: "negative regulation of autophagy in response to cellular starvation by TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of autophagy in response to cellular starvation by TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of macroautophagy by TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of non-specific autophagy by TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of non-specific autophagy by TORC1 signaling" EXACT [GOC:TermGenie] +synonym: "negative regulation of starvation-induced autophagy by TORC1 signal transduction" EXACT [GOC:TermGenie] +synonym: "negative regulation of starvation-induced autophagy by TORC1 signaling" EXACT [GOC:TermGenie] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:0038202 ! TORC1 signaling +intersection_of: GO:0038202 ! TORC1 signaling +intersection_of: negatively_regulates GO:0016236 ! macroautophagy +created_by: dph +creation_date: 2015-10-26T18:34:47Z + +[Term] +id: GO:1904767 +name: octanoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with octanoic acid." [GO_REF:0000067, GOC:kmv, GOC:TermGenie, PMID:19828452] +synonym: "caprylic acid binding" EXACT [CHEBI:28837] +is_a: GO:0005504 ! fatty acid binding +created_by: kmv +creation_date: 2015-10-27T21:11:49Z + +[Term] +id: GO:1904768 +name: all-trans-retinol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with all-trans-retinol." [GO_REF:0000067, GOC:kmv, GOC:TermGenie, PMID:19828452] +is_a: GO:0019841 ! retinol binding +created_by: kmv +creation_date: 2015-10-27T21:14:47Z + +[Term] +id: GO:1904769 +name: isopentadecanoic acid binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with isopentadecanoic acid." [GO_REF:0000067, GOC:kmv, GOC:TermGenie, PMID:19828452] +synonym: "13-methylmyristic acid binding" EXACT [CHEBI:39250] +is_a: GO:0036041 ! long-chain fatty acid binding +created_by: kmv +creation_date: 2015-10-27T21:33:38Z + +[Term] +id: GO:1904770 +name: intramembranous bone morphogenesis +namespace: biological_process +def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686] +synonym: "intramembranous bones morphogenesis" RELATED [GOC:TermGenie] +synonym: "membrane bone morphogenesis" RELATED [GOC:TermGenie] +is_a: GO:0060349 ! bone morphogenesis +created_by: dos +creation_date: 2015-10-28T11:46:04Z + +[Term] +id: GO:1904771 +name: obsolete cellular response to doxorubicin +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:19801496] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-10-28T20:48:30Z + +[Term] +id: GO:1904772 +name: response to tetrachloromethane +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:7852267] +synonym: "response to carbon tetrachloride" EXACT [] +synonym: "response to CCL4" EXACT [] +is_a: GO:0010033 ! response to organic substance +created_by: sl +creation_date: 2015-10-28T20:59:15Z + +[Term] +id: GO:1904773 +name: obsolete cellular response to tetrachloromethane +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:7852267] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "cellular response to carbon tetrachloride" EXACT [] +synonym: "cellular response to CCL4" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2015-10-28T20:59:21Z + +[Term] +id: GO:1904774 +name: negative regulation of ubiquinone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:8125303] +synonym: "down regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "down-regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "down-regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "downregulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "downregulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of coenzyme Q biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquinone anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquinone biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquinone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquinone formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ubiquinone synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010795 ! regulation of ubiquinone biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006744 ! ubiquinone biosynthetic process +relationship: negatively_regulates GO:0006744 ! ubiquinone biosynthetic process +created_by: sl +creation_date: 2015-10-28T21:21:20Z + +[Term] +id: GO:1904775 +name: positive regulation of ubiquinone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:8125303] +synonym: "activation of coenzyme Q biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ubiquinone anabolism" NARROW [GOC:TermGenie] +synonym: "activation of ubiquinone biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of ubiquinone biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ubiquinone formation" NARROW [GOC:TermGenie] +synonym: "activation of ubiquinone synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme Q biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme Q biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of coenzyme Q10 biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q10 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q6 biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q6 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q8 biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q8 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q9 biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of coenzyme Q9 biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of ubiquinone anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquinone biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquinone biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquinone formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ubiquinone synthesis" EXACT [GOC:TermGenie] +is_a: GO:0010795 ! regulation of ubiquinone biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006744 ! ubiquinone biosynthetic process +relationship: positively_regulates GO:0006744 ! ubiquinone biosynthetic process +created_by: sl +creation_date: 2015-10-28T21:21:26Z + +[Term] +id: GO:1904776 +name: regulation of protein localization to cell cortex +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. +synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +is_a: GO:1904375 ! regulation of protein localization to cell periphery +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072697 ! protein localization to cell cortex +relationship: regulates GO:0072697 ! protein localization to cell cortex +created_by: es +creation_date: 2015-10-29T16:55:01Z + +[Term] +id: GO:1904777 +name: negative regulation of protein localization to cell cortex +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. +synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to cell cortex" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to cell cortex" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +is_a: GO:1904376 ! negative regulation of protein localization to cell periphery +is_a: GO:1904776 ! regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072697 ! protein localization to cell cortex +relationship: negatively_regulates GO:0072697 ! protein localization to cell cortex +created_by: es +creation_date: 2015-10-29T16:55:08Z + +[Term] +id: GO:1904778 +name: positive regulation of protein localization to cell cortex +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. +synonym: "activation of protein localisation to cell cortex" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to cell cortex" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] +is_a: GO:1904377 ! positive regulation of protein localization to cell periphery +is_a: GO:1904776 ! regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072697 ! protein localization to cell cortex +relationship: positively_regulates GO:0072697 ! protein localization to cell cortex +created_by: es +creation_date: 2015-10-29T16:55:15Z + +[Term] +id: GO:1904779 +name: regulation of protein localization to centrosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to centrosome." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype). +synonym: "regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071539 ! protein localization to centrosome +relationship: regulates GO:0071539 ! protein localization to centrosome +created_by: es +creation_date: 2015-10-30T11:54:30Z + +[Term] +id: GO:1904780 +name: negative regulation of protein localization to centrosome +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype). +synonym: "down regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to centrosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to centrosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to centrosome" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to centrosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to centrosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1904779 ! regulation of protein localization to centrosome +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071539 ! protein localization to centrosome +relationship: negatively_regulates GO:0071539 ! protein localization to centrosome +created_by: es +creation_date: 2015-10-30T11:54:47Z + +[Term] +id: GO:1904781 +name: positive regulation of protein localization to centrosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to centrosome." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] +comment: An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype). +synonym: "activation of protein localisation to centrosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to centrosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to centrosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to centrosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to centrosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to centrosome" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1904779 ! regulation of protein localization to centrosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071539 ! protein localization to centrosome +relationship: positively_regulates GO:0071539 ! protein localization to centrosome +created_by: es +creation_date: 2015-10-30T11:54:53Z + +[Term] +id: GO:1904782 +name: negative regulation of NMDA glutamate receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:12857] +synonym: "down regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "down-regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "downregulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "inhibition of N-methyl-D-aspartate selective glutamate receptor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NMDA glutamate receptor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of NMDA receptor" NARROW [GOC:TermGenie] +synonym: "negative regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of NMDA receptor" EXACT [GOC:TermGenie] +is_a: GO:1900450 ! negative regulation of glutamate receptor signaling pathway +is_a: GO:2000272 ! negative regulation of signaling receptor activity +is_a: GO:2000310 ! regulation of NMDA receptor activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004972 ! NMDA glutamate receptor activity +relationship: negatively_regulates GO:0004972 ! NMDA glutamate receptor activity +created_by: mr +creation_date: 2015-10-30T19:39:31Z + +[Term] +id: GO:1904783 +name: positive regulation of NMDA glutamate receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:12857] +synonym: "activation of N-methyl-D-aspartate selective glutamate receptor activity" NARROW [GOC:TermGenie] +synonym: "activation of NMDA glutamate receptor activity" NARROW [GOC:TermGenie] +synonym: "activation of NMDA receptor" NARROW [GOC:TermGenie] +synonym: "positive regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "up regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "up-regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of NMDA receptor" EXACT [GOC:TermGenie] +synonym: "upregulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of NMDA receptor" EXACT [GOC:TermGenie] +is_a: GO:1900451 ! positive regulation of glutamate receptor signaling pathway +is_a: GO:2000273 ! positive regulation of signaling receptor activity +is_a: GO:2000310 ! regulation of NMDA receptor activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004972 ! NMDA glutamate receptor activity +relationship: positively_regulates GO:0004972 ! NMDA glutamate receptor activity +created_by: mr +creation_date: 2015-10-30T19:39:37Z + +[Term] +id: GO:1904784 +name: NLRP1 inflammasome complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex." [GO_REF:0000079, GOC:TermGenie, PMID:19124602] +comment: The aggregation, arrangement and bonding together of a set of components to form the NLRP1 inflammasome complex, occurring at the level of an individual cell. +synonym: "NALP1 inflammasome complex assembly" EXACT [GOC:TermGenie] +synonym: "NALP1 inflammasome complex formation" EXACT [GOC:TermGenie] +synonym: "NLRP1 inflammasome complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: ae +creation_date: 2015-11-02T09:39:44Z + +[Term] +id: GO:1904785 +name: regulation of asymmetric protein localization involved in cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination." [GO_REF:0000058, GOC:TermGenie, PMID:17476329] +comment: wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP) +synonym: "regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +is_a: GO:0032880 ! regulation of protein localization +is_a: GO:1905933 ! regulation of cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +relationship: regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +created_by: es +creation_date: 2015-11-03T12:11:06Z + +[Term] +id: GO:1904786 +name: negative regulation of asymmetric protein localization involved in cell fate determination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination." [GO_REF:0000058, GOC:TermGenie, PMID:17476329] +comment: wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP) +synonym: "down regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "down regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down regulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "down regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "down-regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down-regulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "down-regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "downregulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "downregulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "downregulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "downregulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "downregulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "inhibition of asymmetric protein localisation involved in cell fate determination" NARROW [GOC:TermGenie] +synonym: "inhibition of asymmetric protein localization involved in cell fate commitment" NARROW [GOC:TermGenie] +synonym: "inhibition of asymmetric protein localization involved in cell fate determination" NARROW [GOC:TermGenie] +synonym: "inhibition of asymmetric protein localization resulting in cell fate commitment" NARROW [GOC:TermGenie] +synonym: "inhibition of cell fate commitment, asymmetric protein localization" NARROW [GOC:TermGenie] +synonym: "negative regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "negative regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "negative regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "negative regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +is_a: GO:1904785 ! regulation of asymmetric protein localization involved in cell fate determination +is_a: GO:1905934 ! negative regulation of cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +relationship: negatively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +created_by: es +creation_date: 2015-11-03T12:11:13Z + +[Term] +id: GO:1904787 +name: positive regulation of asymmetric protein localization involved in cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination." [GO_REF:0000058, GOC:TermGenie, PMID:17476329] +comment: wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP) +synonym: "activation of asymmetric protein localisation involved in cell fate determination" NARROW [GOC:TermGenie] +synonym: "activation of asymmetric protein localization involved in cell fate commitment" NARROW [GOC:TermGenie] +synonym: "activation of asymmetric protein localization involved in cell fate determination" NARROW [GOC:TermGenie] +synonym: "activation of asymmetric protein localization resulting in cell fate commitment" NARROW [GOC:TermGenie] +synonym: "activation of cell fate commitment, asymmetric protein localization" NARROW [GOC:TermGenie] +synonym: "positive regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "positive regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "positive regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "up regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "up regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up regulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "up regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "up-regulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up-regulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "up-regulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +synonym: "upregulation of asymmetric protein localisation involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "upregulation of asymmetric protein localization involved in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "upregulation of asymmetric protein localization involved in cell fate determination" EXACT [GOC:TermGenie] +synonym: "upregulation of asymmetric protein localization resulting in cell fate commitment" EXACT [GOC:TermGenie] +synonym: "upregulation of cell fate commitment, asymmetric protein localization" EXACT [GOC:TermGenie] +is_a: GO:1904785 ! regulation of asymmetric protein localization involved in cell fate determination +is_a: GO:1905935 ! positive regulation of cell fate determination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +relationship: positively_regulates GO:0045167 ! asymmetric protein localization involved in cell fate determination +created_by: es +creation_date: 2015-11-03T12:11:19Z + +[Term] +id: GO:1904788 +name: obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion." [GO_REF:0000063, GOC:TermGenie, PMID:22144909] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of induction of conjugation with cellular fusion by global transcription regulation from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of conjugation with cellular fusion by regulation of gene-specific transcription from RNA polymerase II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of conjugation with cellular fusion by regulation of global transcription from Pol II promoter" RELATED [GOC:TermGenie] +synonym: "positive regulation of induction of conjugation with cellular fusion by regulation of transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter, global" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: tb +creation_date: 2015-11-04T21:17:08Z + +[Term] +id: GO:1904789 +name: regulation of mitotic actomyosin contractile ring maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance." [GO_REF:0000058, GOC:TermGenie, PMID:24115772] +synonym: "regulation of contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "regulation of cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle" EXACT [GOC:TermGenie] +is_a: GO:0110020 ! regulation of actomyosin structure organization +is_a: GO:1903436 ! regulation of mitotic cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902406 ! mitotic actomyosin contractile ring maintenance +relationship: regulates GO:1902406 ! mitotic actomyosin contractile ring maintenance +created_by: mah +creation_date: 2015-11-06T15:42:49Z + +[Term] +id: GO:1904790 +name: regulation of shelterin complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shelterin complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24270157] +synonym: "regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of telosome assembly" EXACT [] +is_a: GO:0033044 ! regulation of chromosome organization +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071573 ! shelterin complex assembly +relationship: regulates GO:0071573 ! shelterin complex assembly +created_by: nc +creation_date: 2015-11-06T16:13:03Z + +[Term] +id: GO:1904791 +name: negative regulation of shelterin complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24270157] +synonym: "down regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of telosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of telosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of telosome assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of Pot1 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Pot1-Tpz1 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of shelterin complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of telosome assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of telosome assembly" EXACT [] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1904790 ! regulation of shelterin complex assembly +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071573 ! shelterin complex assembly +relationship: negatively_regulates GO:0071573 ! shelterin complex assembly +created_by: nc +creation_date: 2015-11-06T16:13:11Z + +[Term] +id: GO:1904792 +name: positive regulation of shelterin complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of shelterin complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24270157] +synonym: "activation of Pot1 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Pot1-Tpz1 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of shelterin complex formation" NARROW [GOC:TermGenie] +synonym: "activation of telosome assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of telosome assembly" EXACT [] +synonym: "up regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of telosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of telosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Pot1 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Pot1-Tpz1 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of shelterin complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of telosome assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1904790 ! regulation of shelterin complex assembly +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071573 ! shelterin complex assembly +relationship: positively_regulates GO:0071573 ! shelterin complex assembly +created_by: nc +creation_date: 2015-11-06T16:13:18Z + +[Term] +id: GO:1904793 +name: regulation of euchromatin binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of euchromatin binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +is_a: GO:0035561 ! regulation of chromatin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990188 ! euchromatin binding +relationship: regulates GO:1990188 ! euchromatin binding +created_by: nc +creation_date: 2015-11-09T11:43:04Z + +[Term] +id: GO:1904794 +name: negative regulation of euchromatin binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "down regulation of euchromatin binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of euchromatin binding" EXACT [GOC:TermGenie] +synonym: "downregulation of euchromatin binding" EXACT [GOC:TermGenie] +synonym: "inhibition of euchromatin binding" NARROW [GOC:TermGenie] +is_a: GO:0035562 ! negative regulation of chromatin binding +is_a: GO:1904793 ! regulation of euchromatin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990188 ! euchromatin binding +relationship: negatively_regulates GO:1990188 ! euchromatin binding +created_by: nc +creation_date: 2015-11-09T11:43:12Z + +[Term] +id: GO:1904795 +name: positive regulation of euchromatin binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of euchromatin binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "activation of euchromatin binding" NARROW [GOC:TermGenie] +synonym: "up regulation of euchromatin binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of euchromatin binding" EXACT [GOC:TermGenie] +synonym: "upregulation of euchromatin binding" EXACT [GOC:TermGenie] +is_a: GO:0035563 ! positive regulation of chromatin binding +is_a: GO:1904793 ! regulation of euchromatin binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990188 ! euchromatin binding +relationship: positively_regulates GO:1990188 ! euchromatin binding +created_by: nc +creation_date: 2015-11-09T11:43:19Z + +[Term] +id: GO:1904796 +name: regulation of core promoter binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of core promoter binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +is_a: GO:2000677 ! regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001046 ! core promoter sequence-specific DNA binding +relationship: regulates GO:0001046 ! core promoter sequence-specific DNA binding +created_by: nc +creation_date: 2015-11-09T12:32:23Z + +[Term] +id: GO:1904797 +name: negative regulation of core promoter binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "down regulation of core promoter binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of core promoter binding" EXACT [GOC:TermGenie] +synonym: "downregulation of core promoter binding" EXACT [GOC:TermGenie] +synonym: "inhibition of core promoter binding" NARROW [GOC:TermGenie] +is_a: GO:1904796 ! regulation of core promoter binding +is_a: GO:2000678 ! negative regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001046 ! core promoter sequence-specific DNA binding +relationship: negatively_regulates GO:0001046 ! core promoter sequence-specific DNA binding +created_by: nc +creation_date: 2015-11-09T12:32:31Z + +[Term] +id: GO:1904798 +name: positive regulation of core promoter binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of core promoter binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22723415] +synonym: "activation of core promoter binding" NARROW [GOC:TermGenie] +synonym: "up regulation of core promoter binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of core promoter binding" EXACT [GOC:TermGenie] +synonym: "upregulation of core promoter binding" EXACT [GOC:TermGenie] +is_a: GO:1904796 ! regulation of core promoter binding +is_a: GO:2000679 ! positive regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001046 ! core promoter sequence-specific DNA binding +relationship: positively_regulates GO:0001046 ! core promoter sequence-specific DNA binding +created_by: nc +creation_date: 2015-11-09T12:32:38Z + +[Term] +id: GO:1904799 +name: regulation of neuron remodeling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuron remodeling." [GO_REF:0000058, GOC:TermGenie, PMID:21609829] +comment: cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype) +synonym: "regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "regulation of neuronal remodeling" EXACT [GOC:TermGenie] +is_a: GO:0014041 ! regulation of neuron maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016322 ! neuron remodeling +relationship: regulates GO:0016322 ! neuron remodeling +created_by: es +creation_date: 2015-11-09T13:46:52Z + +[Term] +id: GO:1904800 +name: negative regulation of neuron remodeling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling." [GO_REF:0000058, GOC:TermGenie, PMID:21609829] +comment: cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype) +synonym: "down regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "down regulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "down regulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "down-regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "down-regulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "down-regulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "downregulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "downregulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "downregulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "inhibition of axon pruning" NARROW [GOC:TermGenie] +synonym: "inhibition of neuron remodeling" NARROW [GOC:TermGenie] +synonym: "inhibition of neuronal remodeling" NARROW [GOC:TermGenie] +synonym: "negative regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuronal remodeling" EXACT [GOC:TermGenie] +is_a: GO:0014043 ! negative regulation of neuron maturation +is_a: GO:1904799 ! regulation of neuron remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016322 ! neuron remodeling +relationship: negatively_regulates GO:0016322 ! neuron remodeling +created_by: es +creation_date: 2015-11-09T13:47:00Z + +[Term] +id: GO:1904801 +name: positive regulation of neuron remodeling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron remodeling." [GO_REF:0000058, GOC:TermGenie, PMID:21609829] +comment: cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype) +synonym: "activation of axon pruning" NARROW [GOC:TermGenie] +synonym: "activation of neuron remodeling" NARROW [GOC:TermGenie] +synonym: "activation of neuronal remodeling" NARROW [GOC:TermGenie] +synonym: "positive regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "positive regulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "up regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "up regulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "up regulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "up-regulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "up-regulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "up-regulation of neuronal remodeling" EXACT [GOC:TermGenie] +synonym: "upregulation of axon pruning" NARROW [GOC:TermGenie] +synonym: "upregulation of neuron remodeling" EXACT [GOC:TermGenie] +synonym: "upregulation of neuronal remodeling" EXACT [GOC:TermGenie] +is_a: GO:0014042 ! positive regulation of neuron maturation +is_a: GO:1904799 ! regulation of neuron remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016322 ! neuron remodeling +relationship: positively_regulates GO:0016322 ! neuron remodeling +created_by: es +creation_date: 2015-11-09T13:47:07Z + +[Term] +id: GO:1904802 +name: RITS complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a RITS complex." [GO_REF:0000079, GOC:TermGenie, PMID:26443059] +synonym: "RITS complex formation" EXACT [GOC:TermGenie] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +created_by: mah +creation_date: 2015-11-09T16:17:54Z + +[Term] +id: GO:1904803 +name: regulation of translation involved in cellular response to UV +namespace: biological_process +def: "Any regulation of translation that is involved in cellular response to UV." [GO_REF:0000060, GOC:TermGenie, PMID:17369398] +synonym: "regulation of protein anabolism involved in cellular response to UV" EXACT [GOC:TermGenie] +synonym: "regulation of protein biosynthesis involved in cellular response to UV" EXACT [GOC:TermGenie] +synonym: "regulation of protein formation involved in cellular response to UV" EXACT [GOC:TermGenie] +synonym: "regulation of protein synthesis involved in cellular response to UV" EXACT [GOC:TermGenie] +synonym: "regulation of translation involved in cellular response to ultraviolet light stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of translation involved in cellular response to ultraviolet radiation stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of translation involved in cellular response to UV light stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of translation involved in cellular response to UV radiation stimulus" EXACT [GOC:TermGenie] +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0006417 ! regulation of translation +intersection_of: part_of GO:0034644 ! cellular response to UV +relationship: part_of GO:0034644 ! cellular response to UV +created_by: mah +creation_date: 2015-11-10T12:12:41Z + +[Term] +id: GO:1904804 +name: response to latrunculin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:15537703] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097305 ! response to alcohol +created_by: mah +creation_date: 2015-11-10T14:00:38Z + +[Term] +id: GO:1904805 +name: cellular response to latrunculin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:15537703] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1904804 ! response to latrunculin A +created_by: mah +creation_date: 2015-11-10T14:00:46Z + +[Term] +id: GO:1904806 +name: regulation of protein oxidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] +synonym: "regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018158 ! protein oxidation +relationship: regulates GO:0018158 ! protein oxidation +created_by: mec +creation_date: 2015-11-10T14:06:00Z + +[Term] +id: GO:1904807 +name: negative regulation of protein oxidation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] +synonym: "down regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein oxidation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein oxidation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein oxidation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein amino acid oxidation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein oxidation" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:1904806 ! regulation of protein oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018158 ! protein oxidation +relationship: negatively_regulates GO:0018158 ! protein oxidation +created_by: mec +creation_date: 2015-11-10T14:06:08Z + +[Term] +id: GO:1904808 +name: positive regulation of protein oxidation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] +synonym: "activation of protein amino acid oxidation" NARROW [GOC:TermGenie] +synonym: "activation of protein oxidation" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "up regulation of protein oxidation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein oxidation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein amino acid oxidation" EXACT [GOC:TermGenie] +synonym: "upregulation of protein oxidation" EXACT [GOC:TermGenie] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:1904806 ! regulation of protein oxidation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018158 ! protein oxidation +relationship: positively_regulates GO:0018158 ! protein oxidation +created_by: mec +creation_date: 2015-11-10T14:06:15Z + +[Term] +id: GO:1904809 +name: regulation of dense core granule transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] +comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). +synonym: "regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1901950 ! dense core granule transport +relationship: regulates GO:1901950 ! dense core granule transport +created_by: es +creation_date: 2015-11-11T10:40:10Z + +[Term] +id: GO:1904810 +name: negative regulation of dense core granule transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] +comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). +synonym: "down regulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "down regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "downregulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "downregulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "inhibition of dense core granule transport" NARROW [GOC:TermGenie] +synonym: "inhibition of dense core vesicle transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:1903650 ! negative regulation of cytoplasmic transport +is_a: GO:1904809 ! regulation of dense core granule transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1901950 ! dense core granule transport +relationship: negatively_regulates GO:1901950 ! dense core granule transport +created_by: es +creation_date: 2015-11-11T10:40:18Z + +[Term] +id: GO:1904811 +name: positive regulation of dense core granule transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] +comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). +synonym: "activation of dense core granule transport" NARROW [GOC:TermGenie] +synonym: "activation of dense core vesicle transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "up regulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "up regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of dense core vesicle transport" EXACT [GOC:TermGenie] +synonym: "upregulation of dense core granule transport" EXACT [GOC:TermGenie] +synonym: "upregulation of dense core vesicle transport" EXACT [GOC:TermGenie] +is_a: GO:1903651 ! positive regulation of cytoplasmic transport +is_a: GO:1904809 ! regulation of dense core granule transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1901950 ! dense core granule transport +relationship: positively_regulates GO:1901950 ! dense core granule transport +created_by: es +creation_date: 2015-11-11T10:40:25Z + +[Term] +id: GO:1904812 +name: rRNA acetylation involved in maturation of SSU-rRNA +namespace: biological_process +def: "Any rRNA acetylation that is involved in maturation of SSU-rRNA." [GO_REF:0000060, GOC:TermGenie, PMID:25402480] +synonym: "rRNA acetylation involved in processing of 20S pre-rRNA" NARROW [GOC:TermGenie] +synonym: "rRNA acetylation involved in SSU-rRNA maturation" EXACT [GOC:TermGenie] +is_a: GO:1990882 ! rRNA acetylation +intersection_of: GO:1990882 ! rRNA acetylation +intersection_of: part_of GO:0030490 ! maturation of SSU-rRNA +relationship: part_of GO:0030490 ! maturation of SSU-rRNA +created_by: al +creation_date: 2015-11-11T15:38:41Z + +[Term] +id: GO:1904813 +name: ficolin-1-rich granule lumen +namespace: cellular_component +def: "Any membrane-enclosed lumen that is part of a ficolin-1-rich granule." [GO_REF:0000064, GOC:TermGenie, PMID:23650620] +synonym: "ficolin-1-rich granule membrane-enclosed lumen" EXACT [] +synonym: "membrane-enclosed lumen of ficolin granule" RELATED [GOC:TermGenie] +synonym: "membrane-enclosed lumen of ficolin-1 rich granule" EXACT [GOC:TermGenie] +synonym: "membrane-enclosed lumen of ficolin-1-rich granule" EXACT [GOC:TermGenie] +is_a: GO:0070013 ! intracellular organelle lumen +intersection_of: GO:0031974 ! membrane-enclosed lumen +intersection_of: part_of GO:0101002 ! ficolin-1-rich granule +relationship: part_of GO:0101002 ! ficolin-1-rich granule +created_by: mec +creation_date: 2015-11-13T11:58:20Z + +[Term] +id: GO:1904814 +name: regulation of protein localization to chromosome, telomeric region +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:19487455] +synonym: "regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070198 ! protein localization to chromosome, telomeric region +relationship: regulates GO:0070198 ! protein localization to chromosome, telomeric region +created_by: nc +creation_date: 2015-11-16T12:18:43Z + +[Term] +id: GO:1904815 +name: negative regulation of protein localization to chromosome, telomeric region +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:19487455] +synonym: "down regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to telomere" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1904814 ! regulation of protein localization to chromosome, telomeric region +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070198 ! protein localization to chromosome, telomeric region +relationship: negatively_regulates GO:0070198 ! protein localization to chromosome, telomeric region +created_by: nc +creation_date: 2015-11-16T12:18:51Z + +[Term] +id: GO:1904816 +name: positive regulation of protein localization to chromosome, telomeric region +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:19487455] +synonym: "activation of protein localisation to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to telomere" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1904814 ! regulation of protein localization to chromosome, telomeric region +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070198 ! protein localization to chromosome, telomeric region +relationship: positively_regulates GO:0070198 ! protein localization to chromosome, telomeric region +created_by: nc +creation_date: 2015-11-16T12:18:58Z + +[Term] +id: GO:1904817 +name: serous membrane development +namespace: biological_process +def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] +synonym: "serosa development" RELATED [GOC:TermGenie] +synonym: "tunica serosa development" EXACT [GOC:TermGenie] +synonym: "wall of serous sac development" EXACT [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: dph +creation_date: 2015-11-17T19:00:01Z + +[Term] +id: GO:1904818 +name: visceral peritoneum development +namespace: biological_process +def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:1904820 ! peritoneum development +created_by: dph +creation_date: 2015-11-17T19:00:17Z + +[Term] +id: GO:1904819 +name: parietal peritoneum development +namespace: biological_process +def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] +synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:1904820 ! peritoneum development +created_by: dph +creation_date: 2015-11-17T19:00:24Z + +[Term] +id: GO:1904820 +name: peritoneum development +namespace: biological_process +def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] +synonym: "peritonaeum development" RELATED [GOC:TermGenie] +is_a: GO:1904817 ! serous membrane development +created_by: dph +creation_date: 2015-11-18T17:23:51Z + +[Term] +id: GO:1904821 +name: chloroplast disassembly +namespace: biological_process +def: "The disaggregation of a chloroplast into its constituent components." [GO_REF:0000079, GOC:TermGenie, PMID:26494759] +comment: The disaggregation of a chloroplast into its constituent components. +synonym: "chloroplast degradation" RELATED [PMID:26494759] +is_a: GO:0009658 ! chloroplast organization +is_a: GO:1903008 ! organelle disassembly +created_by: lr +creation_date: 2015-11-19T00:41:18Z + +[Term] +id: GO:1904823 +name: purine nucleobase transmembrane transport +namespace: biological_process +def: "The process in which a purine nucleobase is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] +is_a: GO:0006863 ! purine nucleobase transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +created_by: vw +creation_date: 2015-11-19T09:07:56Z + +[Term] +id: GO:1904824 +name: anaphase-promoting complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex." [GO_REF:0000079, GOC:TermGenie, PMID:16950791] +synonym: "anaphase promoting complex assembly" EXACT [GOC:TermGenie] +synonym: "anaphase promoting complex formation" EXACT [GOC:TermGenie] +synonym: "anaphase-promoting complex formation" EXACT [GOC:TermGenie] +synonym: "APC assembly" BROAD [] +synonym: "cyclosome assembly" EXACT [GOC:TermGenie] +synonym: "cyclosome formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2015-11-23T12:28:59Z + +[Term] +id: GO:1904825 +name: protein localization to microtubule plus-end +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end." [GO_REF:0000087, GOC:TermGenie, PMID:24039245] +synonym: "protein localisation to microtubule plus-end" EXACT [GOC:TermGenie] +is_a: GO:1905725 ! protein localization to microtubule end +created_by: mah +creation_date: 2015-11-23T12:34:09Z + +[Term] +id: GO:1904826 +name: regulation of hydrogen sulfide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +synonym: "regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070814 ! hydrogen sulfide biosynthetic process +relationship: regulates GO:0070814 ! hydrogen sulfide biosynthetic process +created_by: rph +creation_date: 2015-11-24T10:15:26Z + +[Term] +id: GO:1904827 +name: negative regulation of hydrogen sulfide biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +synonym: "down regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "inhibition of hydrogen sulfide anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulfide biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulfide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulfide formation" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulfide synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulphide biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen sulphide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1900377 ! negative regulation of secondary metabolite biosynthetic process +is_a: GO:1904826 ! regulation of hydrogen sulfide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070814 ! hydrogen sulfide biosynthetic process +relationship: negatively_regulates GO:0070814 ! hydrogen sulfide biosynthetic process +created_by: rph +creation_date: 2015-11-24T10:15:34Z + +[Term] +id: GO:1904828 +name: positive regulation of hydrogen sulfide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +synonym: "activation of hydrogen sulfide anabolism" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulfide biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulfide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulfide formation" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulfide synthesis" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulphide biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen sulphide biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulfide anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulfide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulfide biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulfide formation" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulfide synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulphide biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen sulphide biosynthetic process" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1900378 ! positive regulation of secondary metabolite biosynthetic process +is_a: GO:1904826 ! regulation of hydrogen sulfide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070814 ! hydrogen sulfide biosynthetic process +relationship: positively_regulates GO:0070814 ! hydrogen sulfide biosynthetic process +created_by: rph +creation_date: 2015-11-24T10:15:41Z + +[Term] +id: GO:1904829 +name: regulation of aortic smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +is_a: GO:1905063 ! regulation of vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035887 ! aortic smooth muscle cell differentiation +relationship: regulates GO:0035887 ! aortic smooth muscle cell differentiation +created_by: rph +creation_date: 2015-11-24T10:20:40Z + +[Term] +id: GO:1904830 +name: negative regulation of aortic smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation +is_a: GO:1905064 ! negative regulation of vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation +relationship: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation +created_by: rph +creation_date: 2015-11-24T10:20:47Z + +[Term] +id: GO:1904831 +name: positive regulation of aortic smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] +synonym: "activation of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation +is_a: GO:1905065 ! positive regulation of vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation +relationship: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation +created_by: rph +creation_date: 2015-11-24T10:20:54Z + +[Term] +id: GO:1904832 +name: negative regulation of removal of superoxide radicals +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22836756] +synonym: "down regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "down regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "down regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "down regulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "down-regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "down-regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "down-regulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "downregulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "downregulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "downregulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular detoxification of superoxide radicals" NARROW [GOC:TermGenie] +synonym: "inhibition of removal of O2-" NARROW [GOC:TermGenie] +synonym: "inhibition of removal of oxygen free radicals" NARROW [GOC:TermGenie] +synonym: "inhibition of removal of superoxide radicals" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "negative regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "negative regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +is_a: GO:1900408 ! negative regulation of cellular response to oxidative stress +is_a: GO:1901032 ! negative regulation of response to reactive oxygen species +is_a: GO:2000121 ! regulation of removal of superoxide radicals +is_a: GO:2000378 ! negative regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019430 ! removal of superoxide radicals +relationship: negatively_regulates GO:0019430 ! removal of superoxide radicals +created_by: rph +creation_date: 2015-11-24T15:30:18Z + +[Term] +id: GO:1904833 +name: positive regulation of removal of superoxide radicals +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22836756] +synonym: "activation of cellular detoxification of superoxide radicals" NARROW [GOC:TermGenie] +synonym: "activation of removal of O2-" NARROW [GOC:TermGenie] +synonym: "activation of removal of oxygen free radicals" NARROW [GOC:TermGenie] +synonym: "activation of removal of superoxide radicals" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "positive regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "positive regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "up regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "up regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "up regulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "up-regulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "up-regulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "up-regulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular detoxification of superoxide radicals" EXACT [GOC:TermGenie] +synonym: "upregulation of removal of O2-" EXACT [GOC:TermGenie] +synonym: "upregulation of removal of oxygen free radicals" EXACT [GOC:TermGenie] +synonym: "upregulation of removal of superoxide radicals" EXACT [GOC:TermGenie] +is_a: GO:1900409 ! positive regulation of cellular response to oxidative stress +is_a: GO:1901033 ! positive regulation of response to reactive oxygen species +is_a: GO:2000121 ! regulation of removal of superoxide radicals +is_a: GO:2000379 ! positive regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019430 ! removal of superoxide radicals +relationship: positively_regulates GO:0019430 ! removal of superoxide radicals +created_by: rph +creation_date: 2015-11-24T15:30:26Z + +[Term] +id: GO:1904834 +name: nuclear CENP-A containing chromatin +namespace: cellular_component +def: "Any CENP-A containing chromatin that is part of nuclear chromatin." [GO_REF:0000064, GOC:TermGenie, PMID:24710126] +synonym: "nuclear centromeric core domain chromatin" RELATED [] +synonym: "nuclear centromeric core region chromatin" EXACT [] +synonym: "nuclear chromatin containing CENP-A" EXACT [] +is_a: GO:0000790 ! nuclear chromatin +is_a: GO:0061638 ! CENP-A containing chromatin +created_by: mah +creation_date: 2015-11-30T12:32:34Z + +[Term] +id: GO:1904835 +name: dorsal root ganglion morphogenesis +namespace: biological_process +def: "The developmental process by which a dorsal root ganglion is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18936100] +synonym: "dorsal root ganglia morphogenesis" RELATED [GOC:TermGenie] +synonym: "DRG morphogenesis" RELATED [GOC:TermGenie] +synonym: "ganglion of dorsal root morphogenesis" EXACT [GOC:TermGenie] +synonym: "ganglion sensorium nervi spinalis morphogenesis" RELATED [GOC:TermGenie] +synonym: "ganglion spinale morphogenesis" RELATED [GOC:TermGenie] +synonym: "ganglion spinalis morphogenesis" EXACT [GOC:TermGenie] +synonym: "posterior root ganglion morphogenesis" RELATED [GOC:TermGenie] +synonym: "spinal ganglion morphogenesis" EXACT [GOC:TermGenie] +synonym: "spinal ganglion part of peripheral nervous system morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0061552 ! ganglion morphogenesis +relationship: part_of GO:1990791 ! dorsal root ganglion development +created_by: bf +creation_date: 2015-12-01T16:41:17Z + +[Term] +id: GO:1904836 +name: facioacoustic ganglion morphogenesis +namespace: biological_process +def: "The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized." [GO_REF:0000083, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] +synonym: "acoustico-facial VII-VIII ganglion complex morphogenesis" EXACT [UBERON:0012175] +synonym: "acousticofacial ganglion morphogenesis" EXACT [GOC:TermGenie] +synonym: "facio-acoustic ganglion complex morphogenesis" RELATED [GOC:TermGenie] +synonym: "facio-acoustic ganglion complex VII-VIII morphogenesis" EXACT [GOC:TermGenie] +synonym: "facio-acoustic ganglion morphogenesis" EXACT [GOC:TermGenie] +synonym: "facio-acoustic VII-VIII ganglion complex morphogenesis" RELATED [GOC:TermGenie] +is_a: GO:0061559 ! cranial ganglion morphogenesis +relationship: part_of GO:1903375 ! facioacoustic ganglion development +created_by: bf +creation_date: 2015-12-01T17:02:06Z + +[Term] +id: GO:1904837 +name: beta-catenin-TCF complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18936100] +synonym: "beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2015-12-03T17:20:26Z + +[Term] +id: GO:1904838 +name: regulation of male germ-line stem cell asymmetric division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division." [GO_REF:0000058, GOC:TermGenie, PMID:19339709] +synonym: "regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:0009786 ! regulation of asymmetric cell division +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000035 ! regulation of stem cell division +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048133 ! male germ-line stem cell asymmetric division +relationship: regulates GO:0048133 ! male germ-line stem cell asymmetric division +created_by: sl +creation_date: 2015-12-05T00:28:31Z + +[Term] +id: GO:1904839 +name: negative regulation of male germ-line stem cell asymmetric division +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division." [GO_REF:0000058, GOC:TermGenie, PMID:19339709] +synonym: "down regulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "down regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "down-regulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "down-regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "downregulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "downregulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "inhibition of male germ-line stem cell asymmetric division" NARROW [GOC:TermGenie] +synonym: "inhibition of male germ-line stem cell renewal" NARROW [GOC:TermGenie] +synonym: "negative regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0045769 ! negative regulation of asymmetric cell division +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1904838 ! regulation of male germ-line stem cell asymmetric division +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048133 ! male germ-line stem cell asymmetric division +relationship: negatively_regulates GO:0048133 ! male germ-line stem cell asymmetric division +created_by: sl +creation_date: 2015-12-05T00:28:39Z + +[Term] +id: GO:1904840 +name: positive regulation of male germ-line stem cell asymmetric division +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division." [GO_REF:0000058, GOC:TermGenie, PMID:19339709] +synonym: "activation of male germ-line stem cell asymmetric division" NARROW [GOC:TermGenie] +synonym: "activation of male germ-line stem cell renewal" NARROW [GOC:TermGenie] +synonym: "positive regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "up regulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "up regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "up-regulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "up-regulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +synonym: "upregulation of male germ-line stem cell asymmetric division" EXACT [GOC:TermGenie] +synonym: "upregulation of male germ-line stem cell renewal" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0045770 ! positive regulation of asymmetric cell division +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1904838 ! regulation of male germ-line stem cell asymmetric division +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048133 ! male germ-line stem cell asymmetric division +relationship: positively_regulates GO:0048133 ! male germ-line stem cell asymmetric division +created_by: sl +creation_date: 2015-12-05T00:28:46Z + +[Term] +id: GO:1904841 +name: TORC2 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a TORC2 complex." [GOC:TermGenie, PMID:20660630] +comment: Interacting selectively and non-covalently with a TORC2 complex, a protein complex that mediates the phosphorylation of protein kinase B +synonym: "mTORC2 binding" NARROW [GOC:TermGenie] +synonym: "rapamycin and nutrient-insensitive TOR complex binding" EXACT [GOC:TermGenie] +synonym: "TOR complex 2 binding" EXACT [GOC:TermGenie] +synonym: "TORC 2 complex binding" EXACT [GOC:TermGenie] +synonym: "TORC2 binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: pf +creation_date: 2015-12-07T16:59:44Z + +[Term] +id: GO:1904842 +name: response to nitroglycerin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25626975] +synonym: "response to nitroglycerine" EXACT [] +synonym: "response to nitroglycerol" EXACT [] +synonym: "response to trinitroglycerin" EXACT [] +synonym: "response to trinitroglycerol" EXACT [] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0010033 ! response to organic substance +is_a: GO:0042493 ! response to drug +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2015-12-07T18:30:47Z + +[Term] +id: GO:1904843 +name: cellular response to nitroglycerin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25626975] +synonym: "cellular response to nitroglycerine" EXACT [] +synonym: "cellular response to nitroglycerol" EXACT [] +synonym: "cellular response to trinitroglycerin" EXACT [] +synonym: "cellular response to trinitroglycerol" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1904842 ! response to nitroglycerin +created_by: sl +creation_date: 2015-12-07T18:30:55Z + +[Term] +id: GO:1904844 +name: response to L-glutamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23185570] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +created_by: sl +creation_date: 2015-12-07T19:39:17Z + +[Term] +id: GO:1904845 +name: cellular response to L-glutamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23185570] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1904844 ! response to L-glutamine +created_by: sl +creation_date: 2015-12-07T19:39:24Z + +[Term] +id: GO:1904846 +name: negative regulation of establishment of bipolar cell polarity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity." [GO_REF:0000058, GOC:TermGenie, PMID:26525038] +synonym: "down regulation of establishment of bipolar cell polarity" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of bipolar cell polarity" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of bipolar cell polarity" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of bipolar cell polarity" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0061172 ! regulation of establishment of bipolar cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061171 ! establishment of bipolar cell polarity +relationship: negatively_regulates GO:0061171 ! establishment of bipolar cell polarity +created_by: al +creation_date: 2015-12-08T15:06:30Z + +[Term] +id: GO:1904847 +name: regulation of cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23233752] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +relationship: regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +created_by: rph +creation_date: 2015-12-10T12:04:01Z + +[Term] +id: GO:1904848 +name: negative regulation of cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23233752] +synonym: "down regulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +synonym: "downregulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +synonym: "inhibition of cell chemotaxis to fibroblast growth factor" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:1904847 ! regulation of cell chemotaxis to fibroblast growth factor +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +relationship: negatively_regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +created_by: rph +creation_date: 2015-12-10T12:04:08Z + +[Term] +id: GO:1904849 +name: positive regulation of cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23233752] +synonym: "activation of cell chemotaxis to fibroblast growth factor" NARROW [GOC:TermGenie] +synonym: "up regulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +synonym: "upregulation of cell chemotaxis to fibroblast growth factor" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1904847 ! regulation of cell chemotaxis to fibroblast growth factor +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +relationship: positively_regulates GO:0035766 ! cell chemotaxis to fibroblast growth factor +created_by: rph +creation_date: 2015-12-10T12:04:16Z + +[Term] +id: GO:1904850 +name: negative regulation of establishment of protein localization to telomere +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "down regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of protein localisation to telomere" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of protein localization to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of protein localization to telomere" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +is_a: GO:0070203 ! regulation of establishment of protein localization to telomere +is_a: GO:1904815 ! negative regulation of protein localization to chromosome, telomeric region +is_a: GO:1904950 ! negative regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070200 ! establishment of protein localization to telomere +relationship: negatively_regulates GO:0070200 ! establishment of protein localization to telomere +created_by: nc +creation_date: 2015-12-10T15:37:51Z + +[Term] +id: GO:1904851 +name: positive regulation of establishment of protein localization to telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "activation of establishment of protein localisation to telomere" NARROW [GOC:TermGenie] +synonym: "activation of establishment of protein localization to chromosome, telomeric region" NARROW [GOC:TermGenie] +synonym: "activation of establishment of protein localization to telomere" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localisation to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localization to chromosome, telomeric region" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:0070203 ! regulation of establishment of protein localization to telomere +is_a: GO:1904816 ! positive regulation of protein localization to chromosome, telomeric region +is_a: GO:1904951 ! positive regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070200 ! establishment of protein localization to telomere +relationship: positively_regulates GO:0070200 ! establishment of protein localization to telomere +created_by: nc +creation_date: 2015-12-10T15:37:58Z + +[Term] +id: GO:1904852 +name: trimethylamine-N-oxide reductase (cytochrome c) complex +namespace: cellular_component +def: "A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:11056172] +comment: An example of this is TorA in E. coli (UniProt ID P33225) in PMID:11056172 (inferred from direct assay). +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2015-12-14T09:11:10Z + +[Term] +id: GO:1904853 +name: protein localization to ascospore wall +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an ascospore wall." [GO_REF:0000087, GOC:TermGenie, PMID:24623719] +synonym: "protein localisation in ascospore wall" EXACT [GOC:TermGenie] +synonym: "protein localisation to ascospore wall" EXACT [GOC:TermGenie] +synonym: "protein localization in ascospore wall" EXACT [GOC:TermGenie] +is_a: GO:0099614 ! protein localization to spore cell wall +created_by: mah +creation_date: 2015-12-14T12:52:50Z + +[Term] +id: GO:1904854 +name: proteasome core complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proteasome core complex." [GOC:TermGenie, PMID:16096059] +synonym: "20S core complex binding" NARROW [GOC:TermGenie] +synonym: "20S proteasome binding" NARROW [GOC:TermGenie] +synonym: "macropain binding" EXACT [GOC:TermGenie] +synonym: "PA28gamma-20S proteasome binding" NARROW [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2015-12-15T11:54:19Z + +[Term] +id: GO:1904855 +name: proteasome regulatory particle binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a proteasome regulatory particle." [GOC:TermGenie, PMID:16096059] +synonym: "19S regulatory particle binding" NARROW [GOC:TermGenie] +synonym: "modulator complex binding" RELATED [GOC:TermGenie] +synonym: "PA700 proteasome activator binding" NARROW [GOC:TermGenie] +synonym: "PA700-dependent proteasome activator binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2015-12-15T11:54:27Z + +[Term] +id: GO:1904856 +name: cytolytic granule lumen +namespace: cellular_component +def: "Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule." [GO_REF:0000064, GOC:TermGenie, PMID:17272266, PMID:21247065] +synonym: "cytolytic granule cytoplasmic membrane-bounded vesicle lumen" EXACT [] +synonym: "cytoplasmic membrane-bounded vesicle lumen of cytolytic granule" EXACT [GOC:TermGenie] +synonym: "cytoplasmic membrane-enclosed vesicle lumen of cytolytic granule" EXACT [GOC:TermGenie] +is_a: GO:0005775 ! vacuolar lumen +is_a: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: GO:0060205 ! cytoplasmic vesicle lumen +intersection_of: part_of GO:0044194 ! cytolytic granule +relationship: part_of GO:0044194 ! cytolytic granule +created_by: mec +creation_date: 2015-12-15T12:51:17Z + +[Term] +id: GO:1904857 +name: regulation of endothelial cell chemotaxis to vascular endothelial growth factor +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:21885851] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:1902547 ! regulation of cellular response to vascular endothelial growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +relationship: regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +created_by: rph +creation_date: 2015-12-16T11:47:44Z + +[Term] +id: GO:1904858 +name: negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:21885851] +synonym: "down regulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "inhibition of endothelial cell chemotaxis to vascular endothelial growth factor" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:1902548 ! negative regulation of cellular response to vascular endothelial growth factor stimulus +is_a: GO:1904857 ! regulation of endothelial cell chemotaxis to vascular endothelial growth factor +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +relationship: negatively_regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +created_by: rph +creation_date: 2015-12-16T11:47:52Z + +[Term] +id: GO:1904859 +name: positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:21885851] +synonym: "activation of endothelial cell chemotaxis to vascular endothelial growth factor" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelial cell chemotaxis to vascular endothelial growth factor" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1904857 ! regulation of endothelial cell chemotaxis to vascular endothelial growth factor +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +relationship: positively_regulates GO:0090668 ! endothelial cell chemotaxis to vascular endothelial growth factor +created_by: rph +creation_date: 2015-12-16T11:48:00Z + +[Term] +id: GO:1904860 +name: DNA synthesis involved in mitotic DNA replication +namespace: biological_process +def: "Any DNA biosynthetic process that is involved in mitotic DNA replication." [GO_REF:0000060, GOC:TermGenie, PMID:16849602] +synonym: "DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA anabolism involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA anabolism involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA anabolism involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA biosynthesis involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA biosynthesis involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in mitotic DNA replication" EXACT [] +synonym: "DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA formation involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA formation involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA formation involved in mitotic DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA formation involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle" RELATED [GOC:TermGenie] +synonym: "DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in mitotic cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in mitotic nuclear cell cycle DNA replication" EXACT [GOC:TermGenie] +synonym: "DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" RELATED [GOC:TermGenie] +is_a: GO:0090592 ! DNA synthesis involved in DNA replication +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0071897 ! DNA biosynthetic process +intersection_of: part_of GO:1902969 ! mitotic DNA replication +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: mah +creation_date: 2015-12-16T12:02:37Z + +[Term] +id: GO:1904861 +name: excitatory synapse assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21670302] +synonym: "excitatory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0007416 ! synapse assembly +created_by: bf +creation_date: 2015-12-17T10:31:26Z + +[Term] +id: GO:1904862 +name: inhibitory synapse assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "inhibitory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0007416 ! synapse assembly +created_by: bf +creation_date: 2015-12-17T10:31:34Z + +[Term] +id: GO:1904863 +name: regulation of beta-catenin-TCF complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904837 ! beta-catenin-TCF complex assembly +relationship: regulates GO:1904837 ! beta-catenin-TCF complex assembly +created_by: bf +creation_date: 2015-12-17T13:50:39Z + +[Term] +id: GO:1904864 +name: negative regulation of beta-catenin-TCF complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18936100] +synonym: "down regulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "down regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "down regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "downregulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "downregulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "downregulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "inhibition of beta-catenin-TCF complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-catenin-TCF complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "inhibition of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1904863 ! regulation of beta-catenin-TCF complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904837 ! beta-catenin-TCF complex assembly +relationship: negatively_regulates GO:1904837 ! beta-catenin-TCF complex assembly +created_by: bf +creation_date: 2015-12-17T13:50:46Z + +[Term] +id: GO:1904865 +name: positive regulation of beta-catenin-TCF complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of beta-catenin-TCF complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of beta-catenin-TCF complex formation" NARROW [GOC:TermGenie] +synonym: "activation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "activation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "activation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "activation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "activation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "up regulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "up regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "up regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +synonym: "upregulation of beta-catenin-TCF complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-catenin-TCF complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-catenin/LEF complex assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of beta-catenin/LEF complex formation" NARROW [GOC:TermGenie] +synonym: "upregulation of beta-catenin/lymphoid enhancer binding factor complex assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of beta-catenin/lymphoid enhancer binding factor complex formation" RELATED [GOC:TermGenie] +synonym: "upregulation of beta-catenin/T-cell factor complex assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of beta-catenin/T-cell factor complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1904863 ! regulation of beta-catenin-TCF complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904837 ! beta-catenin-TCF complex assembly +relationship: positively_regulates GO:1904837 ! beta-catenin-TCF complex assembly +created_by: bf +creation_date: 2015-12-17T13:50:53Z + +[Term] +id: GO:1904866 +name: ventral tegmental area development +namespace: biological_process +def: "The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26548362] +synonym: "a10a development" EXACT [GOC:TermGenie] +synonym: "area tegmentalis ventralis (Tsai) development" RELATED [GOC:TermGenie] +synonym: "area tegmentalis ventralis development" RELATED [GOC:TermGenie] +synonym: "tegmentum ventrale development" RELATED [GOC:TermGenie] +synonym: "ventral brain stem development" RELATED [GOC:TermGenie] +synonym: "ventral tegmental area (Tsai) development" RELATED [GOC:TermGenie] +synonym: "ventral tegmental area of tsai development" EXACT [GOC:TermGenie] +synonym: "ventral tegmental nucleus (Rioch) development" RELATED [GOC:TermGenie] +synonym: "ventral tegmental nucleus (tsai) development" EXACT [GOC:TermGenie] +synonym: "ventral tegmental nucleus of tsai development" EXACT [GOC:TermGenie] +synonym: "ventral tegmentum development" EXACT [Wikipedia:Ventral_tegmental_area] +synonym: "ventromedial mesencephalic tegmentum development" RELATED [GOC:TermGenie] +synonym: "VTA development" BROAD [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0030901 ! midbrain development +created_by: bf +creation_date: 2015-12-17T14:44:18Z + +[Term] +id: GO:1904867 +name: protein localization to Cajal body +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a Cajal body." [GO_REF:0000087, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "protein localization in Cajal body" EXACT [GOC:TermGenie] +is_a: GO:1903405 ! protein localization to nuclear body +created_by: tb +creation_date: 2015-12-17T21:48:18Z + +[Term] +id: GO:1904868 +name: telomerase catalytic core complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex." [GO_REF:0000079, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "TERT-TERC complex formation" RELATED [GOC:TermGenie] +is_a: GO:1905323 ! telomerase holoenzyme complex assembly +created_by: rph +creation_date: 2015-12-18T10:02:45Z + +[Term] +id: GO:1904869 +name: regulation of protein localization to Cajal body +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +is_a: GO:1900180 ! regulation of protein localization to nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904867 ! protein localization to Cajal body +relationship: regulates GO:1904867 ! protein localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:17:31Z + +[Term] +id: GO:1904870 +name: negative regulation of protein localization to Cajal body +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "down regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in Cajal body" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to Cajal body" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in Cajal body" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to Cajal body" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +is_a: GO:1900181 ! negative regulation of protein localization to nucleus +is_a: GO:1904869 ! regulation of protein localization to Cajal body +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904867 ! protein localization to Cajal body +relationship: negatively_regulates GO:1904867 ! protein localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:17:38Z + +[Term] +id: GO:1904871 +name: positive regulation of protein localization to Cajal body +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "activation of protein localisation in Cajal body" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to Cajal body" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in Cajal body" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to Cajal body" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in Cajal body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to Cajal body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in Cajal body" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to Cajal body" EXACT [GOC:TermGenie] +is_a: GO:1900182 ! positive regulation of protein localization to nucleus +is_a: GO:1904869 ! regulation of protein localization to Cajal body +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904867 ! protein localization to Cajal body +relationship: positively_regulates GO:1904867 ! protein localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:17:45Z + +[Term] +id: GO:1904872 +name: regulation of telomerase RNA localization to Cajal body +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090671 ! telomerase RNA localization to Cajal body +relationship: regulates GO:0090671 ! telomerase RNA localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:28:20Z + +[Term] +id: GO:1904873 +name: negative regulation of telomerase RNA localization to Cajal body +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "down regulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "downregulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "inhibition of telomerase RNA localization to Cajal body" NARROW [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1904872 ! regulation of telomerase RNA localization to Cajal body +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090671 ! telomerase RNA localization to Cajal body +relationship: negatively_regulates GO:0090671 ! telomerase RNA localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:28:27Z + +[Term] +id: GO:1904874 +name: positive regulation of telomerase RNA localization to Cajal body +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25467444] +synonym: "activation of telomerase RNA localization to Cajal body" NARROW [GOC:TermGenie] +synonym: "up regulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +synonym: "upregulation of telomerase RNA localization to Cajal body" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1904872 ! regulation of telomerase RNA localization to Cajal body +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090671 ! telomerase RNA localization to Cajal body +relationship: positively_regulates GO:0090671 ! telomerase RNA localization to Cajal body +created_by: nc +creation_date: 2015-12-18T11:28:34Z + +[Term] +id: GO:1904875 +name: regulation of DNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA ligase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:rl, GOC:TermGenie, PMID:17389648] +is_a: GO:0051105 ! regulation of DNA ligation +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003909 ! DNA ligase activity +relationship: regulates GO:0003909 ! DNA ligase activity +created_by: rl +creation_date: 2015-12-18T18:35:30Z + +[Term] +id: GO:1904876 +name: negative regulation of DNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:rl, GOC:TermGenie, PMID:17389648] +synonym: "down regulation of DNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA ligase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA ligase activity" NARROW [GOC:TermGenie] +is_a: GO:0051107 ! negative regulation of DNA ligation +is_a: GO:0051352 ! negative regulation of ligase activity +is_a: GO:1904875 ! regulation of DNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003909 ! DNA ligase activity +relationship: negatively_regulates GO:0003909 ! DNA ligase activity +created_by: rl +creation_date: 2015-12-18T18:35:37Z + +[Term] +id: GO:1904877 +name: positive regulation of DNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA ligase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:rl, GOC:TermGenie, PMID:17389648] +synonym: "activation of DNA ligase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA ligase activity" EXACT [GOC:TermGenie] +is_a: GO:0051106 ! positive regulation of DNA ligation +is_a: GO:0051351 ! positive regulation of ligase activity +is_a: GO:1904875 ! regulation of DNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003909 ! DNA ligase activity +relationship: positively_regulates GO:0003909 ! DNA ligase activity +created_by: rl +creation_date: 2015-12-18T18:35:44Z + +[Term] +id: GO:1904878 +name: negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel." [GO_REF:0000058, GOC:TermGenie, PMID:23071515] +synonym: "down regulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +synonym: "down-regulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +synonym: "downregulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +synonym: "inhibition of generation of L-type calcium current" NARROW [GOC:TermGenie] +synonym: "negative regulation of generation of L-type calcium current" RELATED [] +is_a: GO:1902514 ! regulation of calcium ion transmembrane transport via high voltage-gated calcium channel +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +relationship: negatively_regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +created_by: sl +creation_date: 2015-12-18T22:30:37Z + +[Term] +id: GO:1904879 +name: positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel." [GO_REF:0000058, GOC:TermGenie, PMID:23071515] +synonym: "activation of generation of L-type calcium current" NARROW [GOC:TermGenie] +synonym: "positive regulation of generation of L-type calcium current" RELATED [] +synonym: "up regulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +synonym: "up-regulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +synonym: "upregulation of generation of L-type calcium current" EXACT [GOC:TermGenie] +is_a: GO:1902514 ! regulation of calcium ion transmembrane transport via high voltage-gated calcium channel +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +relationship: positively_regulates GO:0061577 ! calcium ion transmembrane transport via high voltage-gated calcium channel +created_by: sl +creation_date: 2015-12-18T22:30:44Z + +[Term] +id: GO:1904880 +name: response to hydrogen sulfide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24012591] +synonym: "response to dihydridosulfur" EXACT [] +synonym: "response to sulfane" EXACT [] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0010035 ! response to inorganic substance +is_a: GO:0042493 ! response to drug +created_by: sl +creation_date: 2016-01-04T23:56:27Z + +[Term] +id: GO:1904881 +name: cellular response to hydrogen sulfide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24012591] +synonym: "cellular response to dihydridosulfur" EXACT [] +synonym: "cellular response to sulfane" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1904880 ! response to hydrogen sulfide +created_by: sl +creation_date: 2016-01-04T23:56:35Z + +[Term] +id: GO:1904882 +name: regulation of telomerase catalytic core complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904868 ! telomerase catalytic core complex assembly +relationship: regulates GO:1904868 ! telomerase catalytic core complex assembly +created_by: rph +creation_date: 2016-01-05T10:36:01Z + +[Term] +id: GO:1904883 +name: negative regulation of telomerase catalytic core complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "down regulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "downregulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "inhibition of telomerase catalytic core complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of telomerase catalytic core complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1904882 ! regulation of telomerase catalytic core complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904868 ! telomerase catalytic core complex assembly +relationship: negatively_regulates GO:1904868 ! telomerase catalytic core complex assembly +created_by: rph +creation_date: 2016-01-05T10:36:09Z + +[Term] +id: GO:1904884 +name: positive regulation of telomerase catalytic core complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "activation of telomerase catalytic core complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of telomerase catalytic core complex formation" NARROW [GOC:TermGenie] +synonym: "activation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "activation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "up regulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +synonym: "upregulation of telomerase catalytic core complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of telomerase catalytic core complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of TERT-TERC complex assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of TERT-TERC complex formation" RELATED [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1904882 ! regulation of telomerase catalytic core complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904868 ! telomerase catalytic core complex assembly +relationship: positively_regulates GO:1904868 ! telomerase catalytic core complex assembly +created_by: rph +creation_date: 2016-01-05T10:36:16Z + +[Term] +id: GO:1904885 +name: beta-catenin destruction complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17143292, PMID:23169527] +synonym: "23S APC complex assembly" NARROW [GOC:TermGenie] +synonym: "23S APC complex formation" NARROW [GOC:TermGenie] +synonym: "APC-Axin-1-beta-catenin complex assembly" EXACT [GOC:TermGenie] +synonym: "APC-Axin-1-beta-catenin complex formation" EXACT [GOC:TermGenie] +synonym: "Axin-APC-beta-catenin-GSK3B complex assembly" EXACT [GOC:TermGenie] +synonym: "Axin-APC-beta-catenin-GSK3B complex formation" EXACT [GOC:TermGenie] +synonym: "BDC assembly" EXACT [GOC:TermGenie] +synonym: "BDC formation" EXACT [GOC:TermGenie] +synonym: "beta-catenin degradation complex assembly" EXACT [GOC:TermGenie] +synonym: "beta-catenin degradation complex formation" EXACT [GOC:TermGenie] +synonym: "beta-catenin destruction complex formation" EXACT [GOC:TermGenie] +synonym: "destruction complex formation" RELATED [PMID:23169527] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2016-01-05T11:40:55Z + +[Term] +id: GO:1904886 +name: beta-catenin destruction complex disassembly +namespace: biological_process +def: "The disaggregation of a beta-catenin destruction complex into its constituent components." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23169527] +synonym: "23S APC complex disassembly" NARROW [GOC:TermGenie] +synonym: "APC-Axin-1-beta-catenin complex disassembly" EXACT [GOC:TermGenie] +synonym: "Axin-APC-beta-catenin-GSK3B complex disassembly" EXACT [GOC:TermGenie] +synonym: "BDC disassembly" EXACT [GOC:TermGenie] +synonym: "beta-catenin degradation complex disassembly" EXACT [GOC:TermGenie] +synonym: "dissociation of beta-catenin degradation complex" EXACT [GOC:bf, PMID:17318175] +is_a: GO:0032984 ! protein-containing complex disassembly +relationship: part_of GO:0060070 ! canonical Wnt signaling pathway +created_by: bf +creation_date: 2016-01-05T11:41:02Z + +[Term] +id: GO:1904887 +name: Wnt signalosome assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22899650] +synonym: "LRP5/6 signalosome assembly" EXACT [GOC:TermGenie] +synonym: "LRP5/6 signalosome formation" EXACT [GOC:TermGenie] +synonym: "LRP6 signalosome assembly" NARROW [GOC:TermGenie] +synonym: "LRP6 signalosome formation" NARROW [GOC:TermGenie] +synonym: "Wnt signalosome complex assembly" EXACT [GOC:TermGenie] +synonym: "Wnt signalosome complex formation" EXACT [GOC:TermGenie] +synonym: "Wnt signalosome formation" EXACT [GOC:TermGenie] +synonym: "Wnt-LRP5/6 signalosome assembly" EXACT [GOC:TermGenie] +synonym: "Wnt-LRP5/6 signalosome formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: bf +creation_date: 2016-01-05T15:34:36Z + +[Term] +id: GO:1904888 +name: cranial skeletal system development +namespace: biological_process +def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227] +synonym: "cranial skeleton development" NARROW [GOC:TermGenie] +synonym: "craniofacial development" NARROW [PMID:11262227] +synonym: "cranium development" RELATED [GOC:TermGenie] +synonym: "osteocranium development" NARROW [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: bf +creation_date: 2016-01-07T13:45:06Z + +[Term] +id: GO:1904889 +name: regulation of excitatory synapse assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of excitatory synapse assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051963 ! regulation of synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904861 ! excitatory synapse assembly +relationship: regulates GO:1904861 ! excitatory synapse assembly +created_by: bf +creation_date: 2016-01-07T14:35:53Z + +[Term] +id: GO:1904890 +name: negative regulation of excitatory synapse assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "downregulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "inhibition of excitatory synapse assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of excitatory synapse formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051964 ! negative regulation of synapse assembly +is_a: GO:1904889 ! regulation of excitatory synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904861 ! excitatory synapse assembly +relationship: negatively_regulates GO:1904861 ! excitatory synapse assembly +created_by: bf +creation_date: 2016-01-07T14:36:00Z + +[Term] +id: GO:1904891 +name: positive regulation of excitatory synapse assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21670302] +synonym: "activation of excitatory synapse assembly" NARROW [GOC:TermGenie] +synonym: "activation of excitatory synapse formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "up regulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of excitatory synapse formation" EXACT [GOC:TermGenie] +synonym: "upregulation of excitatory synapse assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of excitatory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051965 ! positive regulation of synapse assembly +is_a: GO:1904889 ! regulation of excitatory synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904861 ! excitatory synapse assembly +relationship: positively_regulates GO:1904861 ! excitatory synapse assembly +created_by: bf +creation_date: 2016-01-07T14:36:07Z + +[Term] +id: GO:1904892 +name: regulation of receptor signaling pathway via STAT +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor signaling via STAT." [GO_REF:0000058, GOC:rjd, GOC:TermGenie, PMID:24587195] +synonym: "regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097696 ! receptor signaling pathway via STAT +relationship: regulates GO:0097696 ! receptor signaling pathway via STAT +created_by: pr +creation_date: 2016-01-08T08:14:33Z + +[Term] +id: GO:1904893 +name: negative regulation of receptor signaling pathway via STAT +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT." [GO_REF:0000058, GOC:rjd, GOC:TermGenie, PMID:24587195] +synonym: "down regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of kinase activated-STAT cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of kinase-STAT cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of STAT cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of STAT signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "negative regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1904892 ! regulation of receptor signaling pathway via STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097696 ! receptor signaling pathway via STAT +relationship: negatively_regulates GO:0097696 ! receptor signaling pathway via STAT +created_by: pr +creation_date: 2016-01-08T08:14:41Z + +[Term] +id: GO:1904894 +name: positive regulation of receptor signaling pathway via STAT +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT." [GO_REF:0000058, GOC:rjd, GOC:TermGenie, PMID:24587195] +synonym: "activation of kinase activated-STAT cascade" NARROW [GOC:TermGenie] +synonym: "activation of kinase-STAT cascade" NARROW [GOC:TermGenie] +synonym: "activation of STAT cascade" NARROW [GOC:TermGenie] +synonym: "activation of STAT signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "positive regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "positive regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of STAT signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of kinase activated-STAT cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of kinase-STAT cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of STAT cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of STAT signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1904892 ! regulation of receptor signaling pathway via STAT +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097696 ! receptor signaling pathway via STAT +relationship: positively_regulates GO:0097696 ! receptor signaling pathway via STAT +created_by: pr +creation_date: 2016-01-08T08:14:48Z + +[Term] +id: GO:1904895 +name: ESCRT complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21118109] +synonym: "endosomal sorting complex required for transport assembly" EXACT [GOC:TermGenie] +synonym: "endosomal sorting complex required for transport formation" EXACT [GOC:TermGenie] +synonym: "ESCRT complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pad +creation_date: 2016-01-12T10:27:11Z + +[Term] +id: GO:1904896 +name: ESCRT complex disassembly +namespace: biological_process +def: "The disaggregation of an ESCRT complex into its constituent components." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:21118109] +synonym: "endosomal sorting complex required for transport disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: pad +creation_date: 2016-01-12T10:27:30Z + +[Term] +id: GO:1904897 +name: regulation of hepatic stellate cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15358192] +synonym: "regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048145 ! regulation of fibroblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990922 ! hepatic stellate cell proliferation +relationship: regulates GO:1990922 ! hepatic stellate cell proliferation +created_by: sl +creation_date: 2016-01-14T15:56:59Z + +[Term] +id: GO:1904898 +name: negative regulation of hepatic stellate cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15358192] +synonym: "down regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "down regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of hepatic perisinusoidal cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of hepatic stellate cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of Ito cell proliferation" NARROW [GOC:TermGenie] +synonym: "inhibition of perisinusoidal cell proliferation" NARROW [GOC:TermGenie] +synonym: "negative regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "negative regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048147 ! negative regulation of fibroblast proliferation +is_a: GO:1904897 ! regulation of hepatic stellate cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990922 ! hepatic stellate cell proliferation +relationship: negatively_regulates GO:1990922 ! hepatic stellate cell proliferation +created_by: sl +creation_date: 2016-01-14T15:57:06Z + +[Term] +id: GO:1904899 +name: positive regulation of hepatic stellate cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15358192] +synonym: "activation of hepatic perisinusoidal cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of hepatic stellate cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of Ito cell proliferation" NARROW [GOC:TermGenie] +synonym: "activation of perisinusoidal cell proliferation" NARROW [GOC:TermGenie] +synonym: "positive regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "positive regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "up regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of hepatic perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of hepatic stellate cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of Ito cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of perisinusoidal cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0048146 ! positive regulation of fibroblast proliferation +is_a: GO:1904897 ! regulation of hepatic stellate cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990922 ! hepatic stellate cell proliferation +relationship: positively_regulates GO:1990922 ! hepatic stellate cell proliferation +created_by: sl +creation_date: 2016-01-14T15:57:13Z + +[Term] +id: GO:1904900 +name: negative regulation of myosin II filament organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] +synonym: "down regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "down regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "down regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "down-regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "downregulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "downregulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "downregulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "inhibition of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "inhibition of myosin II filament organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of myosin II filament organization" NARROW [GOC:TermGenie] +synonym: "inhibition of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "negative regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +is_a: GO:0043519 ! regulation of myosin II filament organization +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031038 ! myosin II filament organization +relationship: negatively_regulates GO:0031038 ! myosin II filament organization +created_by: mec +creation_date: 2016-01-15T09:04:54Z + +[Term] +id: GO:1904901 +name: positive regulation of myosin II filament organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myosin II filament organization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] +synonym: "activation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "activation of myosin II filament organisation" NARROW [GOC:TermGenie] +synonym: "activation of myosin II filament organization" NARROW [GOC:TermGenie] +synonym: "activation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "positive regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "up regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "up regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "up regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "up-regulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +synonym: "upregulation of myosin II filament assembly or disassembly" RELATED [GOC:TermGenie] +synonym: "upregulation of myosin II filament organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of myosin II filament organization" EXACT [GOC:TermGenie] +synonym: "upregulation of myosin II polymerization or depolymerization" RELATED [GOC:TermGenie] +is_a: GO:0043519 ! regulation of myosin II filament organization +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031038 ! myosin II filament organization +relationship: positively_regulates GO:0031038 ! myosin II filament organization +created_by: mec +creation_date: 2016-01-15T09:05:02Z + +[Term] +id: GO:1904902 +name: ESCRT III complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20588296] +synonym: "ESCRT III complex formation" EXACT [GOC:TermGenie] +is_a: GO:1904895 ! ESCRT complex assembly +created_by: pad +creation_date: 2016-01-18T13:38:07Z + +[Term] +id: GO:1904903 +name: ESCRT III complex disassembly +namespace: biological_process +def: "The disaggregation of an ESCRT III complex into its constituent components." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20588296] +is_a: GO:1904896 ! ESCRT complex disassembly +created_by: pad +creation_date: 2016-01-18T13:38:14Z + +[Term] +id: GO:1904904 +name: regulation of endothelial cell-matrix adhesion via fibronectin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:19460962] +is_a: GO:0001952 ! regulation of cell-matrix adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +relationship: regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +created_by: bc +creation_date: 2016-01-19T10:23:01Z + +[Term] +id: GO:1904905 +name: negative regulation of endothelial cell-matrix adhesion via fibronectin +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:19460962] +synonym: "down regulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +synonym: "inhibition of endothelial cell-matrix adhesion via fibronectin" NARROW [GOC:TermGenie] +is_a: GO:0001953 ! negative regulation of cell-matrix adhesion +is_a: GO:1904904 ! regulation of endothelial cell-matrix adhesion via fibronectin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +relationship: negatively_regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +created_by: bc +creation_date: 2016-01-19T10:23:09Z + +[Term] +id: GO:1904906 +name: positive regulation of endothelial cell-matrix adhesion via fibronectin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:19460962] +synonym: "activation of endothelial cell-matrix adhesion via fibronectin" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelial cell-matrix adhesion via fibronectin" EXACT [GOC:TermGenie] +is_a: GO:0001954 ! positive regulation of cell-matrix adhesion +is_a: GO:1904904 ! regulation of endothelial cell-matrix adhesion via fibronectin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +relationship: positively_regulates GO:0090674 ! endothelial cell-matrix adhesion via fibronectin +created_by: bc +creation_date: 2016-01-19T10:23:16Z + +[Term] +id: GO:1904907 +name: regulation of maintenance of mitotic sister chromatid cohesion, telomeric +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26373281] +synonym: "regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +is_a: GO:0034182 ! regulation of maintenance of mitotic sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +relationship: regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +created_by: rph +creation_date: 2016-01-19T10:30:29Z + +[Term] +id: GO:1904908 +name: negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26373281] +synonym: "down regulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "down regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "down regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "down regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "downregulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "inhibition of maintenance of mitotic sister chromatid cohesion, telomeric" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of mitotic sister chromatin cohesion at telomere" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of sister chromatin cohesion at telomere at mitosis" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of telomeric mitotic sister chromatin cohesion" NARROW [GOC:TermGenie] +synonym: "negative regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "negative regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +is_a: GO:0034183 ! negative regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:1904907 ! regulation of maintenance of mitotic sister chromatid cohesion, telomeric +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +relationship: negatively_regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +created_by: rph +creation_date: 2016-01-19T10:30:36Z + +[Term] +id: GO:1904909 +name: positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26373281] +synonym: "activation of maintenance of mitotic sister chromatid cohesion, telomeric" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of mitotic sister chromatin cohesion at telomere" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of sister chromatin cohesion at telomere at mitosis" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of telomeric mitotic sister chromatin cohesion" NARROW [GOC:TermGenie] +synonym: "positive regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "positive regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "up regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of mitotic sister chromatid cohesion, telomeric" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of mitotic sister chromatin cohesion at telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of sister chromatin cohesion at telomere at mitosis" EXACT [GOC:TermGenie] +synonym: "upregulation of maintenance of telomeric mitotic sister chromatin cohesion" EXACT [GOC:TermGenie] +is_a: GO:0034184 ! positive regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:1904907 ! regulation of maintenance of mitotic sister chromatid cohesion, telomeric +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +relationship: positively_regulates GO:0099403 ! maintenance of mitotic sister chromatid cohesion, telomeric +created_by: rph +creation_date: 2016-01-19T10:30:43Z + +[Term] +id: GO:1904910 +name: regulation of establishment of RNA localization to telomere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097694 ! establishment of RNA localization to telomere +relationship: regulates GO:0097694 ! establishment of RNA localization to telomere +created_by: rph +creation_date: 2016-01-19T10:34:21Z + +[Term] +id: GO:1904911 +name: negative regulation of establishment of RNA localization to telomere +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "down regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of RNA localisation to telomere" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of RNA localization to telomere" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1904910 ! regulation of establishment of RNA localization to telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097694 ! establishment of RNA localization to telomere +relationship: negatively_regulates GO:0097694 ! establishment of RNA localization to telomere +created_by: rph +creation_date: 2016-01-19T10:34:28Z + +[Term] +id: GO:1904912 +name: positive regulation of establishment of RNA localization to telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "activation of establishment of RNA localisation to telomere" NARROW [GOC:TermGenie] +synonym: "activation of establishment of RNA localization to telomere" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of RNA localisation to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of RNA localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1904910 ! regulation of establishment of RNA localization to telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097694 ! establishment of RNA localization to telomere +relationship: positively_regulates GO:0097694 ! establishment of RNA localization to telomere +created_by: rph +creation_date: 2016-01-19T10:34:35Z + +[Term] +id: GO:1904913 +name: regulation of establishment of protein-containing complex localization to telomere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "regulation of establishment of macromolecular complex localization to telomere" RELATED [] +is_a: GO:0070203 ! regulation of establishment of protein localization to telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +relationship: regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +created_by: rph +creation_date: 2016-01-19T10:38:22Z + +[Term] +id: GO:1904914 +name: negative regulation of establishment of protein-containing complex localization to telomere +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "down regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of macromolecular complex localisation to telomere" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of macromolecular complex localization to telomere" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment of macromolecular complex localization to telomere" RELATED [] +is_a: GO:1904850 ! negative regulation of establishment of protein localization to telomere +is_a: GO:1904913 ! regulation of establishment of protein-containing complex localization to telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +relationship: negatively_regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +created_by: rph +creation_date: 2016-01-19T10:38:29Z + +[Term] +id: GO:1904915 +name: positive regulation of establishment of protein-containing complex localization to telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433] +synonym: "activation of establishment of macromolecular complex localisation to telomere" NARROW [GOC:TermGenie] +synonym: "activation of establishment of macromolecular complex localization to telomere" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment of macromolecular complex localization to telomere" RELATED [] +synonym: "up regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of macromolecular complex localisation to telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of macromolecular complex localization to telomere" EXACT [GOC:TermGenie] +is_a: GO:1904851 ! positive regulation of establishment of protein localization to telomere +is_a: GO:1904913 ! regulation of establishment of protein-containing complex localization to telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +relationship: positively_regulates GO:0097695 ! establishment of protein-containing complex localization to telomere +created_by: rph +creation_date: 2016-01-19T10:38:36Z + +[Term] +id: GO:1904916 +name: transmembrane L-lysine transport from lysosomal lumen to cytosol +namespace: biological_process +def: "The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol." [GO_REF:0000078, GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:1903401 ! L-lysine transmembrane transport +created_by: kmv +creation_date: 2016-01-21T16:27:41Z + +[Term] +id: GO:1904917 +name: L-arginine transmembrane transport from lysosomal lumen to cytosol +namespace: biological_process +def: "The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol." [GO_REF:0000078, GOC:kmv, GOC:TermGenie, PMID:22822152] +synonym: "transmembrane L-arginine transport from lysosomal lumen to cytosol" EXACT [] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:1903400 ! L-arginine transmembrane transport +created_by: kmv +creation_date: 2016-01-21T16:27:48Z + +[Term] +id: GO:1904918 +name: transmembrane L-histidine transport from lysosomal lumen to cytosol +namespace: biological_process +def: "The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol." [GO_REF:0000078, GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0089709 ! L-histidine transmembrane transport +created_by: kmv +creation_date: 2016-01-21T16:27:55Z + +[Term] +id: GO:1904919 +name: transmembrane L-cystine transport from lysosomal lumen to cytosol +namespace: biological_process +def: "The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol." [GO_REF:0000078, GOC:kmv, GOC:TermGenie, PMID:22822152] +is_a: GO:0007041 ! lysosomal transport +is_a: GO:0015811 ! L-cystine transport +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +created_by: kmv +creation_date: 2016-01-21T16:28:02Z + +[Term] +id: GO:1904920 +name: regulation of MAPK cascade involved in axon regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:20203177] +synonym: "regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0043408 ! regulation of MAPK cascade +is_a: GO:0048679 ! regulation of axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1903616 ! MAPK cascade involved in axon regeneration +relationship: regulates GO:1903616 ! MAPK cascade involved in axon regeneration +created_by: kmv +creation_date: 2016-01-25T17:03:35Z + +[Term] +id: GO:1904921 +name: negative regulation of MAPK cascade involved in axon regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:20203177] +synonym: "down regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "down regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "down regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "down regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "down regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "down-regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "down-regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "down-regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "down-regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "downregulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "downregulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "downregulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "downregulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "inhibition of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAP kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAP kinase kinase kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPK signal transduction involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "inhibition of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "inhibition of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of MAPKKK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of mitogen-activated protein kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "negative regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "negative regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "negative regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "negative regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "negative regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "negative regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "negative regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "negative regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0043409 ! negative regulation of MAPK cascade +is_a: GO:0048681 ! negative regulation of axon regeneration +is_a: GO:1904920 ! regulation of MAPK cascade involved in axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1903616 ! MAPK cascade involved in axon regeneration +relationship: negatively_regulates GO:1903616 ! MAPK cascade involved in axon regeneration +created_by: kmv +creation_date: 2016-01-25T17:03:42Z + +[Term] +id: GO:1904922 +name: positive regulation of MAPK cascade involved in axon regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:20203177] +synonym: "activation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAP kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAP kinase kinase kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAPK signal transduction involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "activation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "activation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of MAPKKK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "activation of mitogen-activated protein kinase cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "positive regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "positive regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "positive regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "positive regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "positive regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "positive regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "positive regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "positive regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "up regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "up regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "up regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "up regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "up-regulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "up-regulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "up-regulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "up-regulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of ERK/MAPK cascade involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "upregulation of MAP kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of MAP kinase kinase kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of MAPK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of MAPK signal transduction involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of MAPK signaling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "upregulation of MAPK signalling involved in axon regeneration" RELATED [GOC:TermGenie] +synonym: "upregulation of MAPKKK cascade during sporulation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "upregulation of MAPKKK cascade involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of mitogen-activated protein kinase cascade involved in axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0043410 ! positive regulation of MAPK cascade +is_a: GO:0048680 ! positive regulation of axon regeneration +is_a: GO:1904920 ! regulation of MAPK cascade involved in axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1903616 ! MAPK cascade involved in axon regeneration +relationship: positively_regulates GO:1903616 ! MAPK cascade involved in axon regeneration +created_by: kmv +creation_date: 2016-01-25T17:03:49Z + +[Term] +id: GO:1904923 +name: regulation of autophagy of mitochondrion in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +is_a: GO:0098780 ! response to mitochondrial depolarisation +is_a: GO:1903146 ! regulation of autophagy of mitochondrion +intersection_of: GO:0098780 ! response to mitochondrial depolarisation +intersection_of: regulates GO:0000422 ! autophagy of mitochondrion +created_by: pad +creation_date: 2016-01-26T11:23:50Z + +[Term] +id: GO:1904924 +name: negative regulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +synonym: "down regulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of mitophagy in response to mitochondrial depolarization" NARROW [GOC:TermGenie] +is_a: GO:1901525 ! negative regulation of mitophagy +is_a: GO:1904923 ! regulation of autophagy of mitochondrion in response to mitochondrial depolarization +intersection_of: GO:0098780 ! response to mitochondrial depolarisation +intersection_of: negatively_regulates GO:0000423 ! mitophagy +created_by: pad +creation_date: 2016-01-26T11:23:58Z + +[Term] +id: GO:1904925 +name: positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] +synonym: "activation of mitophagy in response to mitochondrial depolarization" NARROW [GOC:TermGenie] +synonym: "up regulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +is_a: GO:1903599 ! positive regulation of autophagy of mitochondrion +is_a: GO:1904923 ! regulation of autophagy of mitochondrion in response to mitochondrial depolarization +intersection_of: GO:0098780 ! response to mitochondrial depolarisation +intersection_of: positively_regulates GO:0000422 ! autophagy of mitochondrion +created_by: pad +creation_date: 2016-01-26T11:24:05Z + +[Term] +id: GO:1904926 +name: response to palmitoleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25429233] +is_a: GO:0070542 ! response to fatty acid +created_by: mr +creation_date: 2016-01-27T23:07:22Z + +[Term] +id: GO:1904927 +name: cellular response to palmitoleic acid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:25429233] +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:1904926 ! response to palmitoleic acid +created_by: mr +creation_date: 2016-01-27T23:07:31Z + +[Term] +id: GO:1904928 +name: coreceptor activity involved in canonical Wnt signaling pathway +namespace: molecular_function +def: "Any coreceptor activity that is involved in a canonical Wnt signaling pathway." [GO_REF:0000061, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] +synonym: "coreceptor activity involved in canonical Wnt receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in canonical Wnt-activated signaling pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in frizzled-1 receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin" EXACT [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin" RELATED [GOC:TermGenie] +synonym: "Wnt co-receptor activity, canonical signaling" EXACT [GOC:bf] +synonym: "Wnt co-receptor, canonical pathway" EXACT [GOC:bf] +is_a: GO:0071936 ! coreceptor activity involved in Wnt signaling pathway +intersection_of: GO:0015026 ! coreceptor activity +intersection_of: part_of GO:0060070 ! canonical Wnt signaling pathway +relationship: part_of GO:0060070 ! canonical Wnt signaling pathway +created_by: bf +creation_date: 2016-01-28T15:14:46Z + +[Term] +id: GO:1904929 +name: coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway +namespace: molecular_function +def: "Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway." [GO_REF:0000061, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] +synonym: "coreceptor activity involved in non-canonical Wnt signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor activity involved in PCP pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in planar cell polarity pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt receptor signaling pathway, planar cell polarity pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt receptor signalling pathway, planar cell polarity pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt-activated signaling pathway, planar cell polarity pathway" EXACT [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt-JNK signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor activity involved in Wnt-PCP signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in non-canonical Wnt signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in PCP pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt-JNK signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, insoluble ligand activity involved in Wnt-PCP signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in non-canonical Wnt signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in PCP pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt-JNK signaling pathway" RELATED [GOC:TermGenie] +synonym: "coreceptor, soluble ligand activity involved in Wnt-PCP signaling pathway" RELATED [GOC:TermGenie] +synonym: "Wnt co-receptor activity, non-canonical signaling" BROAD [GOC:bf] +synonym: "Wnt co-receptor, non-canonical pathway" BROAD [GOC:bf] +synonym: "Wnt/PCP co-receptor activity" EXACT [PMID:24431302] +is_a: GO:0071936 ! coreceptor activity involved in Wnt signaling pathway +intersection_of: GO:0015026 ! coreceptor activity +intersection_of: part_of GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +relationship: part_of GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +created_by: bf +creation_date: 2016-01-28T15:15:01Z + +[Term] +id: GO:1904930 +name: amphisome membrane +namespace: cellular_component +def: "Any membrane that is part of an amphisome." [GO_REF:0000064, GOC:bhm, GOC:TermGenie, PMID:17984323] +is_a: GO:0000421 ! autophagosome membrane +created_by: pr +creation_date: 2016-01-29T11:40:13Z + +[Term] +id: GO:1904931 +name: MCM complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an MCM complex." [GOC:TermGenie, PMID:12604790] +synonym: "mini-chromosome maintenance complex binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2016-01-29T11:48:10Z + +[Term] +id: GO:1904932 +name: negative regulation of cartilage condensation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17604018] +synonym: "down regulation of cartilage condensation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cartilage condensation" EXACT [GOC:TermGenie] +synonym: "downregulation of cartilage condensation" EXACT [GOC:TermGenie] +synonym: "inhibition of cartilage condensation" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0061037 ! negative regulation of cartilage development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1902026 ! regulation of cartilage condensation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001502 ! cartilage condensation +relationship: negatively_regulates GO:0001502 ! cartilage condensation +created_by: mr +creation_date: 2016-01-29T18:13:39Z + +[Term] +id: GO:1904933 +name: regulation of cell proliferation in midbrain +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] +synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033278 ! cell proliferation in midbrain +relationship: regulates GO:0033278 ! cell proliferation in midbrain +created_by: bf +creation_date: 2016-02-01T13:16:11Z + +[Term] +id: GO:1904934 +name: negative regulation of cell proliferation in midbrain +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] +synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "down regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "downregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "inhibition of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] +synonym: "inhibition of cell proliferation in midbrain" NARROW [GOC:TermGenie] +synonym: "inhibition of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "negative regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:1904933 ! regulation of cell proliferation in midbrain +is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033278 ! cell proliferation in midbrain +relationship: negatively_regulates GO:0033278 ! cell proliferation in midbrain +created_by: bf +creation_date: 2016-02-01T13:16:19Z + +[Term] +id: GO:1904935 +name: positive regulation of cell proliferation in midbrain +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] +synonym: "activation of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] +synonym: "activation of cell proliferation in midbrain" NARROW [GOC:TermGenie] +synonym: "activation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "positive regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "up regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] +synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] +synonym: "upregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:1904933 ! regulation of cell proliferation in midbrain +is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033278 ! cell proliferation in midbrain +relationship: positively_regulates GO:0033278 ! cell proliferation in midbrain +created_by: bf +creation_date: 2016-02-01T13:16:27Z + +[Term] +id: GO:1904936 +name: interneuron migration +namespace: biological_process +def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] +synonym: "inter neuron migration" EXACT [GOC:ah] +synonym: "inter-neuron migration" EXACT [GOC:ah] +is_a: GO:0001764 ! neuron migration +created_by: ah +creation_date: 2016-02-01T14:04:32Z + +[Term] +id: GO:1904937 +name: sensory neuron migration +namespace: biological_process +def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] +is_a: GO:0001764 ! neuron migration +created_by: ah +creation_date: 2016-02-01T14:15:50Z + +[Term] +id: GO:1904938 +name: planar cell polarity pathway involved in axon guidance +namespace: biological_process +def: "Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21106844, PMID:23517308] +synonym: "non-canonical Wnt signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in axon growth cone guidance" RELATED [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in axon guidance" RELATED [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in axon pathfinding" RELATED [GOC:TermGenie] +synonym: "PCP pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "PCP pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "PCP pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "PCP pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in axon guidance" EXACT [GOC:bf] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in axon growth cone guidance" NARROW [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in axon guidance" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in axon pathfinding" EXACT [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in axon growth cone guidance" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in axon guidance" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in axon pathfinding" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling involved in axon guidance" EXACT [GOC:bf] +synonym: "Wnt-PCP signaling pathway involved in axon chemotaxis" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in axon growth cone guidance" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in axon guidance" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in axon pathfinding" RELATED [GOC:TermGenie] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +created_by: bf +creation_date: 2016-02-02T14:46:26Z + +[Term] +id: GO:1904939 +name: regulation of DNA nucleotidylexotransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity." [GO_REF:0000059, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +synonym: "regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of TdT" RELATED [GOC:TermGenie] +synonym: "regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of terminal transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003912 ! DNA nucleotidylexotransferase activity +relationship: regulates GO:0003912 ! DNA nucleotidylexotransferase activity +created_by: bc +creation_date: 2016-02-02T15:15:57Z + +[Term] +id: GO:1904940 +name: negative regulation of DNA nucleotidylexotransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity." [GO_REF:0000059, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +synonym: "down regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of TdT" RELATED [GOC:TermGenie] +synonym: "down regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "down regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of TdT" RELATED [GOC:TermGenie] +synonym: "down-regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of addase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of TdT" RELATED [GOC:TermGenie] +synonym: "downregulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "downregulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of addase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of deoxynucleotidyl terminal transferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of deoxyribonucleic acid nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of deoxyribonucleic nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA nucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of TdT" RELATED [GOC:TermGenie] +synonym: "inhibition of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "inhibition of terminal deoxynucleotide transferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal deoxynucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal deoxyribonucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of terminal transferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of TdT" RELATED [GOC:TermGenie] +synonym: "negative regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of terminal transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1904939 ! regulation of DNA nucleotidylexotransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003912 ! DNA nucleotidylexotransferase activity +relationship: negatively_regulates GO:0003912 ! DNA nucleotidylexotransferase activity +created_by: bc +creation_date: 2016-02-02T15:16:05Z + +[Term] +id: GO:1904941 +name: positive regulation of DNA nucleotidylexotransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity." [GO_REF:0000059, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +synonym: "activation of addase activity" NARROW [GOC:TermGenie] +synonym: "activation of deoxynucleotidyl terminal transferase activity" NARROW [GOC:TermGenie] +synonym: "activation of deoxyribonucleic acid nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of deoxyribonucleic nucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of DNA nucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of TdT" RELATED [GOC:TermGenie] +synonym: "activation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "activation of terminal deoxynucleotide transferase activity" NARROW [GOC:TermGenie] +synonym: "activation of terminal deoxynucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of terminal deoxyribonucleotidyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of terminal transferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of TdT" RELATED [GOC:TermGenie] +synonym: "positive regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of TdT" RELATED [GOC:TermGenie] +synonym: "up regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "up regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of addase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of TdT" RELATED [GOC:TermGenie] +synonym: "up-regulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of addase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxynucleotidyl terminal transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleic acid nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of deoxyribonucleic nucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA nucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of TdT" RELATED [GOC:TermGenie] +synonym: "upregulation of terminal addition enzyme activity" RELATED [GOC:TermGenie] +synonym: "upregulation of terminal deoxynucleotide transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal deoxynucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal deoxyribonucleotidyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of terminal transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1904939 ! regulation of DNA nucleotidylexotransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003912 ! DNA nucleotidylexotransferase activity +relationship: positively_regulates GO:0003912 ! DNA nucleotidylexotransferase activity +created_by: bc +creation_date: 2016-02-02T15:16:12Z + +[Term] +id: GO:1904942 +name: regulation of cardiac ventricle formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +is_a: GO:1901210 ! regulation of cardiac chamber formation +is_a: GO:1904412 ! regulation of cardiac ventricle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003211 ! cardiac ventricle formation +relationship: regulates GO:0003211 ! cardiac ventricle formation +created_by: bc +creation_date: 2016-02-02T16:37:16Z + +[Term] +id: GO:1904943 +name: negative regulation of cardiac ventricle formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac ventricle formation" NARROW [GOC:TermGenie] +is_a: GO:1901211 ! negative regulation of cardiac chamber formation +is_a: GO:1904413 ! negative regulation of cardiac ventricle development +is_a: GO:1904942 ! regulation of cardiac ventricle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003211 ! cardiac ventricle formation +relationship: negatively_regulates GO:0003211 ! cardiac ventricle formation +created_by: bc +creation_date: 2016-02-02T16:37:24Z + +[Term] +id: GO:1904944 +name: positive regulation of cardiac ventricle formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] +synonym: "activation of cardiac ventricle formation" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] +is_a: GO:1901212 ! positive regulation of cardiac chamber formation +is_a: GO:1904414 ! positive regulation of cardiac ventricle development +is_a: GO:1904942 ! regulation of cardiac ventricle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003211 ! cardiac ventricle formation +relationship: positively_regulates GO:0003211 ! cardiac ventricle formation +created_by: bc +creation_date: 2016-02-02T16:37:31Z + +[Term] +id: GO:1904945 +name: obsolete response to cobalt(II) acetate +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:24315322] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: mr +creation_date: 2016-02-02T16:47:52Z + +[Term] +id: GO:1904946 +name: obsolete cellular response to cobalt(II) acetate +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus." [GO_REF:0000071, GOC:mr, GOC:TermGenie, PMID:24315322] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: mr +creation_date: 2016-02-02T16:48:00Z + +[Term] +id: GO:1904947 +name: folate import into mitochondrion +namespace: biological_process +def: "The process in which folic acid is transported from the cytosol, into the mitochondrial matrix." [GO_REF:0000075, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:15140890] +synonym: "folic acid import into mitochondrion" RELATED [] +is_a: GO:0098838 ! folate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: rph +creation_date: 2016-02-03T12:10:14Z + +[Term] +id: GO:1904948 +name: midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron." [GO_REF:0000086, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17331494, PMID:19122665] +synonym: "DA neurogenesis from midbrain floor plate" EXACT [PMID:19122665] +synonym: "mDA neuron differentiation" EXACT [PMID:24287202] +synonym: "midbrain DA neurogenesis" EXACT [PMID:19122665] +synonym: "midbrain dopaminergic neuron production" EXACT [PMID:19122665] +is_a: GO:0021953 ! central nervous system neuron differentiation +is_a: GO:0071542 ! dopaminergic neuron differentiation +relationship: part_of GO:0030901 ! midbrain development +created_by: bf +creation_date: 2016-02-04T14:38:10Z + +[Term] +id: GO:1904949 +name: ATPase complex +namespace: cellular_component +def: "A protein complex which is capable of ATPase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:9606181] +comment: An example of this is VPS4 in Saccharomyces cerevisiae (UniProt ID P52917) in PMID:9606181 (inferred from direct assay). +synonym: "VPS4 complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-02-04T22:13:32Z + +[Term] +id: GO:1904950 +name: negative regulation of establishment of protein localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] +synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "inhibition of establishment of protein localisation" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment of protein localization" NARROW [GOC:TermGenie] +synonym: "inhibition of protein positioning" NARROW [GOC:TermGenie] +synonym: "inhibition of protein recruitment" NARROW [GOC:TermGenie] +synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0070201 ! regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045184 ! establishment of protein localization +relationship: negatively_regulates GO:0045184 ! establishment of protein localization +created_by: mec +creation_date: 2016-02-05T09:59:24Z + +[Term] +id: GO:1904951 +name: positive regulation of establishment of protein localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] +synonym: "activation of establishment of protein localisation" NARROW [GOC:TermGenie] +synonym: "activation of establishment of protein localization" NARROW [GOC:TermGenie] +synonym: "activation of protein positioning" NARROW [GOC:TermGenie] +synonym: "activation of protein recruitment" NARROW [GOC:TermGenie] +synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie] +synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie] +synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:0070201 ! regulation of establishment of protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045184 ! establishment of protein localization +relationship: positively_regulates GO:0045184 ! establishment of protein localization +created_by: mec +creation_date: 2016-02-05T09:59:32Z + +[Term] +id: GO:1904952 +name: hydroxycinnamic acid transport +namespace: biological_process +def: "The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO_REF:0000065, GOC:TermGenie, PMID:26744218] +is_a: GO:0015718 ! monocarboxylic acid transport +created_by: lr +creation_date: 2016-02-05T22:00:38Z + +[Term] +id: GO:1904953 +name: Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250, PMID:22988876, PMID:23517308] +synonym: "frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "Wnt-mediated midbrain DA neuron differentiation" EXACT [PMID:23517308] +is_a: GO:0016055 ! Wnt signaling pathway +intersection_of: GO:0016055 ! Wnt signaling pathway +intersection_of: part_of GO:1904948 ! midbrain dopaminergic neuron differentiation +relationship: part_of GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-08T12:02:07Z + +[Term] +id: GO:1904954 +name: canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22988876] +synonym: "canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "canonical Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "canonical Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:bf] +synonym: "frizzled-1 receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +is_a: GO:0060070 ! canonical Wnt signaling pathway +is_a: GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-09T11:04:46Z + +[Term] +id: GO:1904955 +name: planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22988876] +synonym: "non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" BROAD [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in mDA neuron differentiation" BROAD [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis" BROAD [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" BROAD [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production" BROAD [GOC:TermGenie] +synonym: "non-canonical Wnt-mediated midbrain DA neuron differentiation" BROAD [GOC:bf] +synonym: "PCP pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "PCP pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "PCP pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "PCP pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "PCP pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "planar cell polarity pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation" EXACT [] +synonym: "Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +is_a: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +is_a: GO:1905438 ! non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +intersection_of: GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +intersection_of: part_of GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-09T11:04:56Z + +[Term] +id: GO:1904956 +name: regulation of midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] +synonym: "regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +is_a: GO:1904338 ! regulation of dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +relationship: regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-09T12:00:21Z + +[Term] +id: GO:1904957 +name: negative regulation of midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "inhibition of DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "negative regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +is_a: GO:1904339 ! negative regulation of dopaminergic neuron differentiation +is_a: GO:1904956 ! regulation of midbrain dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +relationship: negatively_regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-09T12:00:29Z + +[Term] +id: GO:1904958 +name: positive regulation of midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] +synonym: "activation of DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "positive regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +is_a: GO:1904340 ! positive regulation of dopaminergic neuron differentiation +is_a: GO:1904956 ! regulation of midbrain dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +relationship: positively_regulates GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-02-09T12:00:36Z + +[Term] +id: GO:1904959 +name: regulation of cytochrome-c oxidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26734017] +synonym: "regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1904732 ! regulation of electron transfer activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004129 ! cytochrome-c oxidase activity +relationship: regulates GO:0004129 ! cytochrome-c oxidase activity +created_by: tb +creation_date: 2016-02-09T22:18:27Z + +[Term] +id: GO:1904960 +name: positive regulation of cytochrome-c oxidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26734017] +synonym: "activation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "activation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "activation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "activation of cytochrome c oxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "activation of cytochrome-c oxidase activity" NARROW [GOC:TermGenie] +synonym: "activation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "activation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "activation of indophenolase" NARROW [GOC:TermGenie] +synonym: "activation of NADH cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "activation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "positive regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "positive regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "positive regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "positive regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "up regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "up regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "up regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "up regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "up regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "up regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "up regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "up-regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "up-regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "up-regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "up-regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "upregulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "upregulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "upregulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "upregulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "upregulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "upregulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "upregulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:1904734 ! positive regulation of electron transfer activity +is_a: GO:1904959 ! regulation of cytochrome-c oxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004129 ! cytochrome-c oxidase activity +relationship: positively_regulates GO:0004129 ! cytochrome-c oxidase activity +created_by: tb +creation_date: 2016-02-09T22:18:43Z + +[Term] +id: GO:1904961 +name: quiescent center organization +namespace: biological_process +def: "The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure." [GO_REF:0000084, GOC:TermGenie, PMID:21233333] +synonym: "quiescent center structural organization" EXACT [] +is_a: GO:0048532 ! anatomical structure arrangement +created_by: tb +creation_date: 2016-02-10T00:11:00Z + +[Term] +id: GO:1904962 +name: plastid to vacuole vesicle-mediated transport +namespace: biological_process +def: "The vesicle-mediated and directed movement of substances from plastid to vacuole." [GO_REF:0000076, GOC:TermGenie, PMID:25281689] +synonym: "plastid to vacuolar carboxypeptidase Y vesicle-mediated transport" RELATED [GOC:TermGenie] +is_a: GO:0007034 ! vacuolar transport +is_a: GO:0016192 ! vesicle-mediated transport +is_a: GO:0016482 ! cytosolic transport +created_by: tb +creation_date: 2016-02-10T00:14:48Z + +[Term] +id: GO:1904963 +name: regulation of phytol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phytol biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24275650] +synonym: "regulation of phytol anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of phytol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of phytol formation" EXACT [GOC:TermGenie] +synonym: "regulation of phytol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0046890 ! regulation of lipid biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033520 ! phytol biosynthetic process +relationship: regulates GO:0033520 ! phytol biosynthetic process +created_by: tb +creation_date: 2016-02-11T00:41:51Z + +[Term] +id: GO:1904964 +name: positive regulation of phytol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:24275650] +synonym: "activation of phytol anabolism" NARROW [GOC:TermGenie] +synonym: "activation of phytol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of phytol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of phytol formation" NARROW [GOC:TermGenie] +synonym: "activation of phytol synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of phytol anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of phytol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of phytol formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of phytol synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phytol anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of phytol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phytol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of phytol formation" EXACT [GOC:TermGenie] +synonym: "up regulation of phytol synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phytol anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of phytol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phytol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of phytol formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of phytol synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phytol anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of phytol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phytol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of phytol formation" EXACT [GOC:TermGenie] +synonym: "upregulation of phytol synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045828 ! positive regulation of isoprenoid metabolic process +is_a: GO:0046889 ! positive regulation of lipid biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +is_a: GO:1904963 ! regulation of phytol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033520 ! phytol biosynthetic process +relationship: positively_regulates GO:0033520 ! phytol biosynthetic process +created_by: tb +creation_date: 2016-02-11T00:42:07Z + +[Term] +id: GO:1904965 +name: regulation of vitamin E biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:20823244] +synonym: "regulation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "regulation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "regulation of tocopherol biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of tocopherol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of vitamin E anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of vitamin E biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of vitamin E formation" EXACT [GOC:TermGenie] +synonym: "regulation of vitamin E synthesis" EXACT [GOC:TermGenie] +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010189 ! vitamin E biosynthetic process +relationship: regulates GO:0010189 ! vitamin E biosynthetic process +created_by: tb +creation_date: 2016-02-12T17:56:55Z + +[Term] +id: GO:1904966 +name: positive regulation of vitamin E biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:20823244] +synonym: "activation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of vitamin E anabolism" NARROW [GOC:TermGenie] +synonym: "activation of vitamin E biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of vitamin E biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of vitamin E formation" NARROW [GOC:TermGenie] +synonym: "activation of vitamin E synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of tocopherol biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of tocopherol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin E anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin E biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin E formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of vitamin E synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up regulation of tocopherol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of tocopherol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin E anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin E biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin E biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin E formation" EXACT [GOC:TermGenie] +synonym: "up regulation of vitamin E synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "up-regulation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "up-regulation of tocopherol biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of tocopherol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin E anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin E biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin E biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin E formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vitamin E synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-tocopherol biosynthesis" NARROW [GOC:TermGenie] +synonym: "upregulation of alpha-tocopherol biosynthetic process" NARROW [GOC:TermGenie] +synonym: "upregulation of tocopherol biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of tocopherol biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin E anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin E biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin E biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin E formation" EXACT [GOC:TermGenie] +synonym: "upregulation of vitamin E synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0046136 ! positive regulation of vitamin metabolic process +is_a: GO:1904965 ! regulation of vitamin E biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010189 ! vitamin E biosynthetic process +relationship: positively_regulates GO:0010189 ! vitamin E biosynthetic process +created_by: tb +creation_date: 2016-02-12T17:57:03Z + +[Term] +id: GO:1904967 +name: regulation of monopolar spindle attachment to meiosis I kinetochore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation." [GO_REF:0000058, GOC:TermGenie, PMID:23770679] +synonym: "regulation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [] +synonym: "regulation of attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "regulation of monopolar attachment" EXACT [GOC:TermGenie] +synonym: "regulation of sister kinetochore mono-orientation" EXACT [GOC:TermGenie] +is_a: GO:0051988 ! regulation of attachment of spindle microtubules to kinetochore +is_a: GO:0060629 ! regulation of homologous chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051455 ! monopolar spindle attachment to meiosis I kinetochore +relationship: regulates GO:0051455 ! monopolar spindle attachment to meiosis I kinetochore +created_by: mah +creation_date: 2016-02-15T15:19:12Z + +[Term] +id: GO:1904968 +name: positive regulation of monopolar spindle attachment to meiosis I kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation." [GO_REF:0000058, GOC:TermGenie, PMID:23770679] +synonym: "activation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "activation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" NARROW [GOC:TermGenie] +synonym: "activation of attachment of spindle microtubules to kinetochore involved in meiosis I" NARROW [GOC:TermGenie] +synonym: "activation of monopolar attachment" NARROW [GOC:TermGenie] +synonym: "activation of sister kinetochore mono-orientation" NARROW [GOC:TermGenie] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [] +synonym: "positive regulation of attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "positive regulation of monopolar attachment" EXACT [GOC:TermGenie] +synonym: "positive regulation of sister kinetochore mono-orientation" EXACT [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up regulation of attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "up regulation of monopolar attachment" EXACT [GOC:TermGenie] +synonym: "up regulation of sister kinetochore mono-orientation" EXACT [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [GOC:TermGenie] +synonym: "up-regulation of attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "up-regulation of monopolar attachment" EXACT [GOC:TermGenie] +synonym: "up-regulation of sister kinetochore mono-orientation" EXACT [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore during meiosis I" RELATED [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation" EXACT [GOC:TermGenie] +synonym: "upregulation of attachment of spindle microtubules to kinetochore involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "upregulation of monopolar attachment" EXACT [GOC:TermGenie] +synonym: "upregulation of sister kinetochore mono-orientation" EXACT [GOC:TermGenie] +is_a: GO:0051987 ! positive regulation of attachment of spindle microtubules to kinetochore +is_a: GO:0060903 ! positive regulation of meiosis I +is_a: GO:1904967 ! regulation of monopolar spindle attachment to meiosis I kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051455 ! monopolar spindle attachment to meiosis I kinetochore +relationship: positively_regulates GO:0051455 ! monopolar spindle attachment to meiosis I kinetochore +created_by: mah +creation_date: 2016-02-15T15:19:20Z + +[Term] +id: GO:1904969 +name: slow muscle cell migration +namespace: biological_process +def: "The orderly movement of a slow muscle cell from one site to another." [GO_REF:0000091, GOC:TermGenie, GOC:ymb, PMID:14667409, PMID:15572133, PMID:25534553] +comment: The directional migration of a slow muscle cell from one site to another within the embryo. +synonym: "slow-twitch muscle cell migration" EXACT [PMID:14667409] +is_a: GO:0110122 ! myotube cell migration +created_by: ymb +creation_date: 2016-02-16T21:20:11Z + +[Term] +id: GO:1904970 +name: brush border assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border." [GO_REF:0000079, GOC:lb, GOC:TermGenie, PMID:24725409] +synonym: "brush border formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +created_by: tb +creation_date: 2016-02-17T00:58:30Z + +[Term] +id: GO:1904971 +name: regulation of viral translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral translation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:19666601] +synonym: "regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "regulation of viral protein synthesis" EXACT [GOC:TermGenie] +is_a: GO:0050792 ! regulation of viral process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019081 ! viral translation +relationship: regulates GO:0019081 ! viral translation +created_by: bhm +creation_date: 2016-02-17T15:52:59Z + +[Term] +id: GO:1904972 +name: negative regulation of viral translation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of viral translation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:19666601] +synonym: "down regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "down regulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of viral translation" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of viral translation" EXACT [GOC:TermGenie] +synonym: "downregulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "downregulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of viral translation" EXACT [GOC:TermGenie] +synonym: "inhibition of viral protein anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of viral protein biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of viral protein biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of viral protein formation" NARROW [GOC:TermGenie] +synonym: "inhibition of viral protein synthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of viral translation" NARROW [GOC:TermGenie] +synonym: "negative regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of viral protein synthesis" EXACT [GOC:TermGenie] +is_a: GO:0048525 ! negative regulation of viral process +is_a: GO:1904971 ! regulation of viral translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019081 ! viral translation +relationship: negatively_regulates GO:0019081 ! viral translation +created_by: bhm +creation_date: 2016-02-17T15:53:08Z + +[Term] +id: GO:1904973 +name: positive regulation of viral translation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral translation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:19666601] +synonym: "activation of viral protein anabolism" NARROW [GOC:TermGenie] +synonym: "activation of viral protein biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of viral protein biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of viral protein formation" NARROW [GOC:TermGenie] +synonym: "activation of viral protein synthesis" NARROW [GOC:TermGenie] +synonym: "activation of viral translation" NARROW [GOC:TermGenie] +synonym: "positive regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "up regulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of viral translation" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral translation" EXACT [GOC:TermGenie] +synonym: "upregulation of viral protein anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of viral protein biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of viral protein biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of viral protein formation" EXACT [GOC:TermGenie] +synonym: "upregulation of viral protein synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of viral translation" EXACT [GOC:TermGenie] +is_a: GO:0048524 ! positive regulation of viral process +is_a: GO:1904971 ! regulation of viral translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019081 ! viral translation +relationship: positively_regulates GO:0019081 ! viral translation +created_by: bhm +creation_date: 2016-02-17T15:53:15Z + +[Term] +id: GO:1904974 +name: heparanase complex +namespace: cellular_component +def: "A protein complex which is capable of heparanase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:12927802] +comment: An example of this is HPSE in human (Q9Y251) in PMID:12927802 (inferred from direct assay). +synonym: "HEPS complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-02-18T11:50:39Z + +[Term] +id: GO:1904975 +name: response to bleomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11553781] +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901652 ! response to peptide +created_by: mah +creation_date: 2016-02-18T15:21:23Z + +[Term] +id: GO:1904976 +name: cellular response to bleomycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11553781] +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:1901653 ! cellular response to peptide +is_a: GO:1904975 ! response to bleomycin +created_by: mah +creation_date: 2016-02-18T15:21:31Z + +[Term] +id: GO:1904977 +name: lymphatic endothelial cell migration +namespace: biological_process +def: "The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel." [GO_REF:0000091, GOC:TermGenie, PMID:25745057] +is_a: GO:0043542 ! endothelial cell migration +relationship: part_of GO:0036303 ! lymph vessel morphogenesis +created_by: dgh +creation_date: 2016-02-18T20:49:43Z + +[Term] +id: GO:1904978 +name: regulation of endosome organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endosome organization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22511594] +synonym: "regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007032 ! endosome organization +relationship: regulates GO:0007032 ! endosome organization +created_by: pad +creation_date: 2016-02-22T19:21:01Z + +[Term] +id: GO:1904979 +name: negative regulation of endosome organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22511594] +synonym: "down regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "down regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "downregulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of endosome organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of endosome organization" NARROW [GOC:TermGenie] +synonym: "inhibition of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1904978 ! regulation of endosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007032 ! endosome organization +relationship: negatively_regulates GO:0007032 ! endosome organization +created_by: pad +creation_date: 2016-02-22T19:21:08Z + +[Term] +id: GO:1904980 +name: positive regulation of endosome organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endosome organization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22511594] +synonym: "activation of endosome organisation" NARROW [GOC:TermGenie] +synonym: "activation of endosome organization" NARROW [GOC:TermGenie] +synonym: "activation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "up regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of endosome organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of endosome organization" EXACT [GOC:TermGenie] +synonym: "upregulation of endosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1904978 ! regulation of endosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007032 ! endosome organization +relationship: positively_regulates GO:0007032 ! endosome organization +created_by: pad +creation_date: 2016-02-22T19:21:16Z + +[Term] +id: GO:1904981 +name: maltose transmembrane transport +namespace: biological_process +def: "The process in which maltose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:11136464] +is_a: GO:0015768 ! maltose transport +is_a: GO:0034219 ! carbohydrate transmembrane transport +created_by: vw +creation_date: 2016-02-28T21:14:04Z + +[Term] +id: GO:1904982 +name: sucrose transmembrane transport +namespace: biological_process +def: "The process in which sucrose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:11136464] +is_a: GO:0015770 ! sucrose transport +is_a: GO:0034219 ! carbohydrate transmembrane transport +created_by: vw +creation_date: 2016-02-28T21:16:51Z + +[Term] +id: GO:1904983 +name: glycine import into mitochondrion +namespace: biological_process +def: "The process in which glycine is transported from the cytosol, into the mitochondrial matrix." [GO_REF:0000078, GOC:TermGenie, PMID:26821380] +synonym: "transmembrane glycine transport from cytosol to mitochondrion" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015816 ! glycine transport +is_a: GO:0043090 ! amino acid import +is_a: GO:0098655 ! cation transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2016-02-28T21:53:44Z + +[Term] +id: GO:1904984 +name: regulation of quinolinate biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:12140278, PMID:19843166] +synonym: "regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +is_a: GO:0062012 ! regulation of small molecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019805 ! quinolinate biosynthetic process +relationship: regulates GO:0019805 ! quinolinate biosynthetic process +created_by: bf +creation_date: 2016-02-29T15:54:12Z + +[Term] +id: GO:1904985 +name: negative regulation of quinolinate biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:12140278, PMID:19843166] +synonym: "down regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "down regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "downregulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of quinolinate anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of quinolinate biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of quinolinate biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of quinolinate formation" NARROW [GOC:TermGenie] +synonym: "inhibition of quinolinate synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1904984 ! regulation of quinolinate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019805 ! quinolinate biosynthetic process +relationship: negatively_regulates GO:0019805 ! quinolinate biosynthetic process +created_by: bf +creation_date: 2016-02-29T15:54:21Z + +[Term] +id: GO:1904986 +name: positive regulation of quinolinate biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of quinolinate anabolism" NARROW [GOC:TermGenie] +synonym: "activation of quinolinate biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of quinolinate biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of quinolinate formation" NARROW [GOC:TermGenie] +synonym: "activation of quinolinate synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "up regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of quinolinate synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of quinolinate anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of quinolinate biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of quinolinate biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of quinolinate formation" EXACT [GOC:TermGenie] +synonym: "upregulation of quinolinate synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1904984 ! regulation of quinolinate biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019805 ! quinolinate biosynthetic process +relationship: positively_regulates GO:0019805 ! quinolinate biosynthetic process +created_by: bf +creation_date: 2016-02-29T15:54:29Z + +[Term] +id: GO:1904987 +name: regulation of endothelial cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042118 ! endothelial cell activation +relationship: regulates GO:0042118 ! endothelial cell activation +created_by: bc +creation_date: 2016-02-29T16:16:09Z + +[Term] +id: GO:1904988 +name: negative regulation of endothelial cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] +synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie] +synonym: "inhibition of endothelial cell activation" NARROW [GOC:TermGenie] +is_a: GO:0050866 ! negative regulation of cell activation +is_a: GO:1904987 ! regulation of endothelial cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042118 ! endothelial cell activation +relationship: negatively_regulates GO:0042118 ! endothelial cell activation +created_by: bc +creation_date: 2016-02-29T16:16:18Z + +[Term] +id: GO:1904989 +name: positive regulation of endothelial cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] +synonym: "activation of endothelial cell activation" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie] +is_a: GO:0050867 ! positive regulation of cell activation +is_a: GO:1904987 ! regulation of endothelial cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042118 ! endothelial cell activation +relationship: positively_regulates GO:0042118 ! endothelial cell activation +created_by: bc +creation_date: 2016-02-29T16:16:25Z + +[Term] +id: GO:1904990 +name: regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26554819] +synonym: "regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +is_a: GO:0060159 ! regulation of dopamine receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +relationship: regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +created_by: kmv +creation_date: 2016-02-29T22:42:16Z + +[Term] +id: GO:1904991 +name: negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26554819] +synonym: "down regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "downregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of adenylate cyclase-inhibiting dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine receptor, adenylate cyclase inhibiting pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of dopamine receptor, adenylyl cyclase inhibiting pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "inhibition of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:0060160 ! negative regulation of dopamine receptor signaling pathway +is_a: GO:1904990 ! regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +relationship: negatively_regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +created_by: kmv +creation_date: 2016-02-29T22:42:25Z + +[Term] +id: GO:1904992 +name: positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:26554819] +synonym: "activation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of dopamine receptor, adenylate cyclase inhibiting pathway" NARROW [GOC:TermGenie] +synonym: "activation of dopamine receptor, adenylyl cyclase inhibiting pathway" NARROW [GOC:TermGenie] +synonym: "activation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "activation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine receptor, adenylate cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway" RELATED [GOC:TermGenie] +synonym: "upregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:0060161 ! positive regulation of dopamine receptor signaling pathway +is_a: GO:1904990 ! regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +relationship: positively_regulates GO:0007195 ! adenylate cyclase-inhibiting dopamine receptor signaling pathway +created_by: kmv +creation_date: 2016-02-29T22:42:33Z + +[Term] +id: GO:1904993 +name: obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in positive regulation of G2/M transition of mitotic cell cycle." [GO_REF:0000060, GOC:TermGenie, PMID:24728197] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "activation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry" NARROW [GOC:TermGenie] +synonym: "positive regulation of CDK activity involved in positive regulation of G2/M transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "positive regulation of CDK activity involved in positive regulation of mitotic entry" EXACT [GOC:TermGenie] +synonym: "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of mitotic entry" EXACT [GOC:TermGenie] +synonym: "stimulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle" NARROW [GOC:TermGenie] +synonym: "stimulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry" NARROW [GOC:TermGenie] +synonym: "up regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle" EXACT [GOC:TermGenie] +synonym: "upregulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-03-01T00:59:41Z + +[Term] +id: GO:1904994 +name: regulation of leukocyte adhesion to vascular endothelial cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23897866] +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +relationship: regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +created_by: bc +creation_date: 2016-03-01T10:59:00Z + +[Term] +id: GO:1904995 +name: negative regulation of leukocyte adhesion to vascular endothelial cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23897866] +synonym: "down regulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +synonym: "inhibition of leukocyte adhesion to vascular endothelial cell" NARROW [GOC:TermGenie] +is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion +is_a: GO:1904994 ! regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +relationship: negatively_regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +created_by: bc +creation_date: 2016-03-01T10:59:08Z + +[Term] +id: GO:1904996 +name: positive regulation of leukocyte adhesion to vascular endothelial cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23897866] +synonym: "activation of leukocyte adhesion to vascular endothelial cell" NARROW [GOC:TermGenie] +synonym: "up regulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte adhesion to vascular endothelial cell" EXACT [GOC:TermGenie] +is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion +is_a: GO:1904994 ! regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +relationship: positively_regulates GO:0061756 ! leukocyte adhesion to vascular endothelial cell +created_by: bc +creation_date: 2016-03-01T10:59:22Z + +[Term] +id: GO:1904997 +name: regulation of leukocyte adhesion to arterial endothelial cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22267480] +is_a: GO:1904994 ! regulation of leukocyte adhesion to vascular endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +relationship: regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +created_by: bc +creation_date: 2016-03-01T11:04:49Z + +[Term] +id: GO:1904998 +name: negative regulation of leukocyte adhesion to arterial endothelial cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22267480] +synonym: "down regulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +synonym: "downregulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +synonym: "inhibition of leukocyte adhesion to arterial endothelial cell" NARROW [GOC:TermGenie] +is_a: GO:1904995 ! negative regulation of leukocyte adhesion to vascular endothelial cell +is_a: GO:1904997 ! regulation of leukocyte adhesion to arterial endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +relationship: negatively_regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +created_by: bc +creation_date: 2016-03-01T11:04:57Z + +[Term] +id: GO:1904999 +name: positive regulation of leukocyte adhesion to arterial endothelial cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22267480] +synonym: "activation of leukocyte adhesion to arterial endothelial cell" NARROW [GOC:TermGenie] +synonym: "up regulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +synonym: "upregulation of leukocyte adhesion to arterial endothelial cell" EXACT [GOC:TermGenie] +is_a: GO:1904996 ! positive regulation of leukocyte adhesion to vascular endothelial cell +is_a: GO:1904997 ! regulation of leukocyte adhesion to arterial endothelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +relationship: positively_regulates GO:0061757 ! leukocyte adhesion to arterial endothelial cell +created_by: bc +creation_date: 2016-03-01T11:05:05Z + +[Term] +id: GO:1905000 +name: regulation of membrane repolarization during atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:21098446] +synonym: "regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +is_a: GO:0060372 ! regulation of atrial cardiac muscle cell membrane repolarization +is_a: GO:0098910 ! regulation of atrial cardiac muscle cell action potential +is_a: GO:1905031 ! regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +relationship: regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-01T13:28:05Z + +[Term] +id: GO:1905001 +name: negative regulation of membrane repolarization during atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:21098446] +synonym: "down regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "down regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "down regulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "down-regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "down-regulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "downregulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "downregulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "inhibition of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "inhibition of membrane repolarization during atrial cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "negative regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +is_a: GO:1903948 ! negative regulation of atrial cardiac muscle cell action potential +is_a: GO:1905000 ! regulation of membrane repolarization during atrial cardiac muscle cell action potential +is_a: GO:1905032 ! negative regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +relationship: negatively_regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-01T13:28:13Z + +[Term] +id: GO:1905002 +name: positive regulation of membrane repolarization during atrial cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:21098446] +synonym: "activation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "activation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "activation of membrane repolarization during atrial cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "positive regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "up regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "up regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "up regulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "up-regulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "up-regulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of atrial repolarization" RELATED [GOC:TermGenie] +synonym: "upregulation of electrocardiogram QRS complex" RELATED [GOC:TermGenie] +synonym: "upregulation of membrane repolarization during atrial cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1903949 ! positive regulation of atrial cardiac muscle cell action potential +is_a: GO:1905000 ! regulation of membrane repolarization during atrial cardiac muscle cell action potential +is_a: GO:1905033 ! positive regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +relationship: positively_regulates GO:0098914 ! membrane repolarization during atrial cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-01T13:28:21Z + +[Term] +id: GO:1905003 +name: picolinic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving picolinic acid." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19843166] +synonym: "picolinate metabolism" EXACT [CHEBI:38184] +synonym: "picolinic acid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006725 ! cellular aromatic compound metabolic process +is_a: GO:0032787 ! monocarboxylic acid metabolic process +is_a: GO:0072524 ! pyridine-containing compound metabolic process +created_by: bf +creation_date: 2016-03-01T14:06:28Z + +[Term] +id: GO:1905004 +name: picolinic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of picolinic acid." [GO_REF:0000068, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19843166] +synonym: "picolinate biosynthesis" EXACT [CHEBI:38184] +synonym: "picolinate biosynthetic process" EXACT [CHEBI:38184] +synonym: "picolinic acid anabolism" EXACT [GOC:TermGenie] +synonym: "picolinic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "picolinic acid formation" EXACT [GOC:TermGenie] +synonym: "picolinic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0019438 ! aromatic compound biosynthetic process +is_a: GO:0072330 ! monocarboxylic acid biosynthetic process +is_a: GO:0072525 ! pyridine-containing compound biosynthetic process +is_a: GO:1905003 ! picolinic acid metabolic process +created_by: bf +creation_date: 2016-03-01T14:06:35Z + +[Term] +id: GO:1905005 +name: regulation of epithelial to mesenchymal transition involved in endocardial cushion formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +is_a: GO:0062042 ! regulation of cardiac epithelial to mesenchymal transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +relationship: regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +created_by: rl +creation_date: 2016-03-01T15:38:39Z + +[Term] +id: GO:1905006 +name: negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "down regulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelial to mesenchymal transition involved in endocardial cushion formation" NARROW [GOC:TermGenie] +is_a: GO:0062044 ! negative regulation of cardiac epithelial to mesenchymal transition +is_a: GO:1905005 ! regulation of epithelial to mesenchymal transition involved in endocardial cushion formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +relationship: negatively_regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +created_by: rl +creation_date: 2016-03-01T15:38:47Z + +[Term] +id: GO:1905007 +name: positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "activation of epithelial to mesenchymal transition involved in endocardial cushion formation" NARROW [GOC:TermGenie] +synonym: "up regulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelial to mesenchymal transition involved in endocardial cushion formation" EXACT [GOC:TermGenie] +is_a: GO:0062043 ! positive regulation of cardiac epithelial to mesenchymal transition +is_a: GO:1905005 ! regulation of epithelial to mesenchymal transition involved in endocardial cushion formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +relationship: positively_regulates GO:0003198 ! epithelial to mesenchymal transition involved in endocardial cushion formation +created_by: rl +creation_date: 2016-03-01T15:38:54Z + +[Term] +id: GO:1905008 +name: regulation of L-lysine import across plasma membrane +namespace: biological_process +alt_id: GO:0010805 +def: "Any process that modulates the frequency, rate or extent of L-lysine import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:7499219] +synonym: "regulation of L-lysine import into cell" EXACT [] +synonym: "regulation of lysine import" BROAD [] +synonym: "regulation of lysine uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097639 ! L-lysine import across plasma membrane +relationship: regulates GO:0097639 ! L-lysine import across plasma membrane +created_by: sl +creation_date: 2016-03-02T00:15:49Z + +[Term] +id: GO:1905009 +name: negative regulation of L-lysine import across plasma membrane +namespace: biological_process +alt_id: GO:0010806 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:7499219] +synonym: "down regulation of L-lysine import into cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-lysine import into cell" EXACT [GOC:TermGenie] +synonym: "downregulation of L-lysine import into cell" EXACT [GOC:TermGenie] +synonym: "inhibition of L-lysine import into cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-lysine import into cell" EXACT [] +synonym: "negative regulation of lysine import" BROAD [] +synonym: "negative regulation of lysine uptake" EXACT [GOC:dph, GOC:tb] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1905008 ! regulation of L-lysine import across plasma membrane +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097639 ! L-lysine import across plasma membrane +relationship: negatively_regulates GO:0097639 ! L-lysine import across plasma membrane +created_by: sl +creation_date: 2016-03-02T00:15:57Z + +[Term] +id: GO:1905010 +name: positive regulation of L-lysine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-lysine import into cell." [GO_REF:0000058, GOC:TermGenie, PMID:7499219] +synonym: "activation of L-lysine import into cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-lysine import into cell" EXACT [] +synonym: "up regulation of L-lysine import into cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-lysine import into cell" EXACT [GOC:TermGenie] +synonym: "upregulation of L-lysine import into cell" EXACT [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:1905008 ! regulation of L-lysine import across plasma membrane +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097639 ! L-lysine import across plasma membrane +relationship: positively_regulates GO:0097639 ! L-lysine import across plasma membrane +created_by: sl +creation_date: 2016-03-02T00:16:04Z + +[Term] +id: GO:1905011 +name: transmembrane phosphate ion transport from cytosol to vacuole +namespace: biological_process +alt_id: GO:0007037 +def: "The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen." [GO_REF:0000078, GOC:TermGenie, PMID:26554016] +synonym: "vacuolar phosphate transport" BROAD [] +is_a: GO:0034486 ! vacuolar transmembrane transport +is_a: GO:0035435 ! phosphate ion transmembrane transport +created_by: tb +creation_date: 2016-03-03T00:34:12Z + +[Term] +id: GO:1905012 +name: regulation of 'de novo' NAD biosynthetic process from tryptophan +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:12140278, PMID:19843166] +synonym: "regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +is_a: GO:0030808 ! regulation of nucleotide biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:0090357 ! regulation of tryptophan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +relationship: regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +created_by: bf +creation_date: 2016-03-03T10:00:50Z + +[Term] +id: GO:1905013 +name: negative regulation of 'de novo' NAD biosynthetic process from tryptophan +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:12140278, PMID:19843166] +synonym: "down regulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "down regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "down-regulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "down-regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "downregulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "downregulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "inhibition of 'de novo' NAD biosynthetic process from tryptophan" NARROW [GOC:TermGenie] +synonym: "inhibition of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "negative regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +is_a: GO:0030809 ! negative regulation of nucleotide biosynthetic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:1905012 ! regulation of 'de novo' NAD biosynthetic process from tryptophan +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +relationship: negatively_regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +created_by: bf +creation_date: 2016-03-03T10:01:00Z + +[Term] +id: GO:1905014 +name: positive regulation of 'de novo' NAD biosynthetic process from tryptophan +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of 'de novo' NAD biosynthetic process from tryptophan" NARROW [GOC:TermGenie] +synonym: "activation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "positive regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "up regulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "up regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "up-regulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "up-regulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +synonym: "upregulation of 'de novo' NAD biosynthetic process from tryptophan" EXACT [GOC:TermGenie] +synonym: "upregulation of de novo NAD biosynthetic process from tryptophan" RELATED [GOC:TermGenie] +is_a: GO:0030810 ! positive regulation of nucleotide biosynthetic process +is_a: GO:0051197 ! positive regulation of coenzyme metabolic process +is_a: GO:0090358 ! positive regulation of tryptophan metabolic process +is_a: GO:1905012 ! regulation of 'de novo' NAD biosynthetic process from tryptophan +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +relationship: positively_regulates GO:0034354 ! 'de novo' NAD biosynthetic process from tryptophan +created_by: bf +creation_date: 2016-03-03T10:01:10Z + +[Term] +id: GO:1905015 +name: regulation of isoleucine-tRNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004822 ! isoleucine-tRNA ligase activity +relationship: regulates GO:0004822 ! isoleucine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:00:48Z + +[Term] +id: GO:1905016 +name: negative regulation of isoleucine-tRNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "down regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "inhibition of isoleucine translase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucine-transfer RNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucine-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of isoleucyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "negative regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +is_a: GO:1903631 ! negative regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905015 ! regulation of isoleucine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004822 ! isoleucine-tRNA ligase activity +relationship: negatively_regulates GO:0004822 ! isoleucine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:00:57Z + +[Term] +id: GO:1905017 +name: positive regulation of isoleucine-tRNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "activation of isoleucine translase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucine-transfer RNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucine-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of isoleucyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-isoleucine:tRNAIle ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "positive regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucine translase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucine-transfer RNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucine-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of isoleucyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [GOC:TermGenie] +is_a: GO:1903632 ! positive regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905015 ! regulation of isoleucine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004822 ! isoleucine-tRNA ligase activity +relationship: positively_regulates GO:0004822 ! isoleucine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:01:06Z + +[Term] +id: GO:1905018 +name: regulation of methionine-tRNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of MetRS activity" EXACT [GOC:TermGenie] +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004825 ! methionine-tRNA ligase activity +relationship: regulates GO:0004825 ! methionine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:02:39Z + +[Term] +id: GO:1905019 +name: negative regulation of methionine-tRNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "down regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "inhibition of L-methionine:tRNAMet ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of methionine translase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methionine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methionyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methionyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methionyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of methionyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of MetRS activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of MetRS activity" EXACT [GOC:TermGenie] +is_a: GO:1903631 ! negative regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905018 ! regulation of methionine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004825 ! methionine-tRNA ligase activity +relationship: negatively_regulates GO:0004825 ! methionine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:02:48Z + +[Term] +id: GO:1905020 +name: positive regulation of methionine-tRNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:1665486] +synonym: "activation of L-methionine:tRNAMet ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "activation of methionine translase activity" NARROW [GOC:TermGenie] +synonym: "activation of methionine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of methionyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of methionyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of methionyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of methionyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of MetRS activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of MetRS activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-methionine:tRNAMet ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of methionine translase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methionine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methionyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methionyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methionyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of methionyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of MetRS activity" EXACT [GOC:TermGenie] +is_a: GO:1903632 ! positive regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905018 ! regulation of methionine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004825 ! methionine-tRNA ligase activity +relationship: positively_regulates GO:0004825 ! methionine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:02:57Z + +[Term] +id: GO:1905021 +name: regulation of threonine-tRNA ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:8049265] +synonym: "regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of TRS" RELATED [GOC:TermGenie] +is_a: GO:1903630 ! regulation of aminoacyl-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004829 ! threonine-tRNA ligase activity +relationship: regulates GO:0004829 ! threonine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:12:23Z + +[Term] +id: GO:1905022 +name: negative regulation of threonine-tRNA ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:8049265] +synonym: "down regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of TRS" RELATED [GOC:TermGenie] +synonym: "down-regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of TRS" RELATED [GOC:TermGenie] +synonym: "downregulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of TRS" RELATED [GOC:TermGenie] +synonym: "inhibition of L-threonine:tRNAThr ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of threonine translase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonine-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonyl ribonucleic synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of threonyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of TRS" RELATED [GOC:TermGenie] +synonym: "negative regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of TRS" RELATED [GOC:TermGenie] +is_a: GO:1903631 ! negative regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905021 ! regulation of threonine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004829 ! threonine-tRNA ligase activity +relationship: negatively_regulates GO:0004829 ! threonine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:12:32Z + +[Term] +id: GO:1905023 +name: positive regulation of threonine-tRNA ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:8049265] +synonym: "activation of L-threonine:tRNAThr ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "activation of threonine translase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonine-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonine-tRNA ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonyl ribonucleic synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonyl-transfer ribonucleate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonyl-transfer ribonucleic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonyl-transfer RNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of threonyl-tRNA synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of TRS" RELATED [GOC:TermGenie] +synonym: "positive regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of TRS" RELATED [GOC:TermGenie] +synonym: "up regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of TRS" RELATED [GOC:TermGenie] +synonym: "up-regulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of TRS" RELATED [GOC:TermGenie] +synonym: "upregulation of L-threonine:tRNAThr ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of threonine translase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonine-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonine-tRNA ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonyl ribonucleic synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonyl-transfer ribonucleate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonyl-transfer ribonucleic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonyl-transfer RNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of threonyl-tRNA synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of TRS" RELATED [GOC:TermGenie] +is_a: GO:1903632 ! positive regulation of aminoacyl-tRNA ligase activity +is_a: GO:1905021 ! regulation of threonine-tRNA ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004829 ! threonine-tRNA ligase activity +relationship: positively_regulates GO:0004829 ! threonine-tRNA ligase activity +created_by: sl +creation_date: 2016-03-03T19:12:41Z + +[Term] +id: GO:1905024 +name: regulation of membrane repolarization during ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19893015] +synonym: "regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "regulation of ventricular repolarization" RELATED [GOC:TermGenie] +is_a: GO:0060307 ! regulation of ventricular cardiac muscle cell membrane repolarization +is_a: GO:0098911 ! regulation of ventricular cardiac muscle cell action potential +is_a: GO:1905031 ! regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +relationship: regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-04T11:19:02Z + +[Term] +id: GO:1905025 +name: negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19893015] +synonym: "down regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "down regulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "down regulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "down-regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "down-regulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "down-regulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "downregulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "downregulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "downregulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "inhibition of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "inhibition of membrane repolarization during ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "inhibition of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "negative regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "negative regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "negative regulation of ventricular repolarization" RELATED [GOC:TermGenie] +is_a: GO:1903946 ! negative regulation of ventricular cardiac muscle cell action potential +is_a: GO:1905024 ! regulation of membrane repolarization during ventricular cardiac muscle cell action potential +is_a: GO:1905032 ! negative regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +relationship: negatively_regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-04T11:19:12Z + +[Term] +id: GO:1905026 +name: positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19893015] +synonym: "activation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "activation of membrane repolarization during ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "activation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "positive regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "positive regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "positive regulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "up regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "up regulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "up regulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "up-regulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "up-regulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "up-regulation of ventricular repolarization" RELATED [GOC:TermGenie] +synonym: "upregulation of electrocardiogram T wave" RELATED [GOC:TermGenie] +synonym: "upregulation of membrane repolarization during ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of regulation of ventricular cardiac muscle repolarization" RELATED [GOC:TermGenie] +synonym: "upregulation of ventricular repolarization" RELATED [GOC:TermGenie] +is_a: GO:1903947 ! positive regulation of ventricular cardiac muscle cell action potential +is_a: GO:1905024 ! regulation of membrane repolarization during ventricular cardiac muscle cell action potential +is_a: GO:1905033 ! positive regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +relationship: positively_regulates GO:0098915 ! membrane repolarization during ventricular cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-04T11:19:21Z + +[Term] +id: GO:1905027 +name: regulation of membrane depolarization during AV node cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19726871] +synonym: "regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0098904 ! regulation of AV node cell action potential +is_a: GO:1900825 ! regulation of membrane depolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086045 ! membrane depolarization during AV node cell action potential +relationship: regulates GO:0086045 ! membrane depolarization during AV node cell action potential +created_by: rph +creation_date: 2016-03-04T13:46:06Z + +[Term] +id: GO:1905028 +name: negative regulation of membrane depolarization during AV node cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19726871] +synonym: "down regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down regulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane depolarization during atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of membrane depolarization during AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "inhibition of membrane depolarization during AV node cell action potential" NARROW [GOC:TermGenie] +synonym: "negative regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "negative regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1900826 ! negative regulation of membrane depolarization during cardiac muscle cell action potential +is_a: GO:1903950 ! negative regulation of AV node cell action potential +is_a: GO:1905027 ! regulation of membrane depolarization during AV node cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086045 ! membrane depolarization during AV node cell action potential +relationship: negatively_regulates GO:0086045 ! membrane depolarization during AV node cell action potential +created_by: rph +creation_date: 2016-03-04T13:46:15Z + +[Term] +id: GO:1905029 +name: positive regulation of membrane depolarization during AV node cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:19726871] +synonym: "activation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of membrane depolarization during AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "activation of membrane depolarization during AV node cell action potential" NARROW [GOC:TermGenie] +synonym: "positive regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "positive regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up regulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane depolarization during AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane depolarization during AV node cell action potential" EXACT [GOC:TermGenie] +is_a: GO:1900827 ! positive regulation of membrane depolarization during cardiac muscle cell action potential +is_a: GO:1903951 ! positive regulation of AV node cell action potential +is_a: GO:1905027 ! regulation of membrane depolarization during AV node cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086045 ! membrane depolarization during AV node cell action potential +relationship: positively_regulates GO:0086045 ! membrane depolarization during AV node cell action potential +created_by: rph +creation_date: 2016-03-04T13:46:24Z + +[Term] +id: GO:1905030 +name: voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential +namespace: molecular_function +def: "Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential." [GO_REF:0000061, GOC:TermGenie, ISBN:9780071120005] +subset: goslim_synapse +synonym: "voltage gated ion channel activity involved in regulation of post-synaptic membrane potential" EXACT [GOC:TermGenie] +synonym: "voltage gated ion channel activity involved in regulation of postsynaptic membrane potential" EXACT [GOC:TermGenie] +synonym: "voltage-dependent ion channel activity involved in regulation of post-synaptic membrane potential" EXACT [GOC:TermGenie] +synonym: "voltage-dependent ion channel activity involved in regulation of postsynaptic membrane potential" EXACT [GOC:TermGenie] +synonym: "voltage-gated ion channel activity involved in regulation of post-synaptic membrane potential" EXACT [GOC:TermGenie] +is_a: GO:0005244 ! voltage-gated ion channel activity +intersection_of: GO:0005244 ! voltage-gated ion channel activity +intersection_of: part_of GO:0060078 ! regulation of postsynaptic membrane potential +relationship: part_of GO:0060078 ! regulation of postsynaptic membrane potential +created_by: dos +creation_date: 2016-03-04T15:51:54Z + +[Term] +id: GO:1905031 +name: regulation of membrane repolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:23157812] +is_a: GO:0098901 ! regulation of cardiac muscle cell action potential +is_a: GO:0098903 ! regulation of membrane repolarization during action potential +is_a: GO:0099623 ! regulation of cardiac muscle cell membrane repolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +relationship: regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-07T10:24:34Z + +[Term] +id: GO:1905032 +name: negative regulation of membrane repolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:23157812] +synonym: "down regulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane repolarization during cardiac muscle cell action potential" NARROW [GOC:TermGenie] +is_a: GO:0034766 ! negative regulation of ion transmembrane transport +is_a: GO:0045759 ! negative regulation of action potential +is_a: GO:1905031 ! regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +relationship: negatively_regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-07T10:24:44Z + +[Term] +id: GO:1905033 +name: positive regulation of membrane repolarization during cardiac muscle cell action potential +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:23157812] +synonym: "activation of membrane repolarization during cardiac muscle cell action potential" NARROW [GOC:TermGenie] +synonym: "up regulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane repolarization during cardiac muscle cell action potential" EXACT [GOC:TermGenie] +is_a: GO:0034767 ! positive regulation of ion transmembrane transport +is_a: GO:0045760 ! positive regulation of action potential +is_a: GO:1905031 ! regulation of membrane repolarization during cardiac muscle cell action potential +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +relationship: positively_regulates GO:0086013 ! membrane repolarization during cardiac muscle cell action potential +created_by: rph +creation_date: 2016-03-07T10:24:53Z + +[Term] +id: GO:1905034 +name: regulation of antifungal innate immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of an antifungal innate immune response." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:22470487] +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:1900150 ! regulation of defense response to fungus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061760 ! antifungal innate immune response +relationship: regulates GO:0061760 ! antifungal innate immune response +created_by: dph +creation_date: 2016-03-07T20:07:54Z + +[Term] +id: GO:1905035 +name: negative regulation of antifungal innate immune response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:22470487] +synonym: "down regulation of antifungal innate immune response" EXACT [GOC:TermGenie] +synonym: "down-regulation of antifungal innate immune response" EXACT [GOC:TermGenie] +synonym: "downregulation of antifungal innate immune response" EXACT [GOC:TermGenie] +synonym: "inhibition of antifungal innate immune response" NARROW [GOC:TermGenie] +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:1905034 ! regulation of antifungal innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061760 ! antifungal innate immune response +relationship: negatively_regulates GO:0061760 ! antifungal innate immune response +created_by: dph +creation_date: 2016-03-07T20:08:05Z + +[Term] +id: GO:1905036 +name: positive regulation of antifungal innate immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:22470487] +synonym: "activation of antifungal innate immune response" NARROW [GOC:TermGenie] +synonym: "up regulation of antifungal innate immune response" EXACT [GOC:TermGenie] +synonym: "up-regulation of antifungal innate immune response" EXACT [GOC:TermGenie] +synonym: "upregulation of antifungal innate immune response" EXACT [GOC:TermGenie] +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:1905034 ! regulation of antifungal innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061760 ! antifungal innate immune response +relationship: positively_regulates GO:0061760 ! antifungal innate immune response +created_by: dph +creation_date: 2016-03-07T20:08:26Z + +[Term] +id: GO:1905037 +name: autophagosome organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome." [GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22186024] +synonym: "autophagic vacuole organization" EXACT [GOC:TermGenie] +synonym: "initial autophagic vacuole organization" RELATED [GOC:TermGenie] +is_a: GO:0007033 ! vacuole organization +relationship: part_of GO:0016236 ! macroautophagy +created_by: bf +creation_date: 2016-03-08T14:18:10Z + +[Term] +id: GO:1905038 +name: regulation of membrane lipid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:25954280] +synonym: "regulation of membrane lipid metabolism" EXACT [GOC:TermGenie] +is_a: GO:0019216 ! regulation of lipid metabolic process +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006643 ! membrane lipid metabolic process +relationship: regulates GO:0006643 ! membrane lipid metabolic process +created_by: tb +creation_date: 2016-03-08T20:41:32Z + +[Term] +id: GO:1905039 +name: carboxylic acid transmembrane transport +namespace: biological_process +def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563] +is_a: GO:0046942 ! carboxylic acid transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1903825 ! organic acid transmembrane transport +created_by: vw +creation_date: 2016-03-09T15:33:53Z + +[Term] +id: GO:1905040 +name: otic placode development +namespace: biological_process +def: "The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] +synonym: "auditory placode development" RELATED [GOC:TermGenie] +synonym: "ear placode development" RELATED [GOC:TermGenie] +synonym: "ear/otic placode development" RELATED [GOC:TermGenie] +synonym: "octaval placode development" RELATED [GOC:TermGenie] +synonym: "octaval VIII placode development" RELATED [GOC:TermGenie] +synonym: "placoda otica development" EXACT [GOC:TermGenie] +is_a: GO:0071696 ! ectodermal placode development +created_by: bf +creation_date: 2016-03-10T09:30:20Z + +[Term] +id: GO:1905041 +name: regulation of epithelium regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelium regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23221517] +synonym: "regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0061041 ! regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990399 ! epithelium regeneration +relationship: regulates GO:1990399 ! epithelium regeneration +created_by: rph +creation_date: 2016-03-11T10:58:53Z + +[Term] +id: GO:1905042 +name: negative regulation of epithelium regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23221517] +synonym: "down regulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "down regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelium regeneration" NARROW [GOC:TermGenie] +synonym: "inhibition of regeneration of epithelium" NARROW [GOC:TermGenie] +synonym: "negative regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:1905041 ! regulation of epithelium regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990399 ! epithelium regeneration +relationship: negatively_regulates GO:1990399 ! epithelium regeneration +created_by: rph +creation_date: 2016-03-11T10:59:03Z + +[Term] +id: GO:1905043 +name: positive regulation of epithelium regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelium regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23221517] +synonym: "activation of epithelium regeneration" NARROW [GOC:TermGenie] +synonym: "activation of regeneration of epithelium" NARROW [GOC:TermGenie] +synonym: "positive regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "up regulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "up regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of regeneration of epithelium" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelium regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of regeneration of epithelium" EXACT [GOC:TermGenie] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:1905041 ! regulation of epithelium regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990399 ! epithelium regeneration +relationship: positively_regulates GO:1990399 ! epithelium regeneration +created_by: rph +creation_date: 2016-03-11T10:59:12Z + +[Term] +id: GO:1905044 +name: regulation of Schwann cell proliferation involved in axon regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22393241] +is_a: GO:0010624 ! regulation of Schwann cell proliferation +is_a: GO:0048679 ! regulation of axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +relationship: regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +created_by: rph +creation_date: 2016-03-11T14:47:35Z + +[Term] +id: GO:1905045 +name: negative regulation of Schwann cell proliferation involved in axon regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22393241] +synonym: "down regulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "inhibition of Schwann cell proliferation involved in axon regeneration" NARROW [GOC:TermGenie] +is_a: GO:0010626 ! negative regulation of Schwann cell proliferation +is_a: GO:0048681 ! negative regulation of axon regeneration +is_a: GO:1905044 ! regulation of Schwann cell proliferation involved in axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +relationship: negatively_regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +created_by: rph +creation_date: 2016-03-11T14:47:45Z + +[Term] +id: GO:1905046 +name: positive regulation of Schwann cell proliferation involved in axon regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22393241] +synonym: "activation of Schwann cell proliferation involved in axon regeneration" NARROW [GOC:TermGenie] +synonym: "up regulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of Schwann cell proliferation involved in axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0010625 ! positive regulation of Schwann cell proliferation +is_a: GO:0048680 ! positive regulation of axon regeneration +is_a: GO:1905044 ! regulation of Schwann cell proliferation involved in axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +relationship: positively_regulates GO:0014011 ! Schwann cell proliferation involved in axon regeneration +created_by: rph +creation_date: 2016-03-11T14:47:54Z + +[Term] +id: GO:1905047 +name: mitotic spindle pole body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body." [GOC:TermGenie, PMID:24963130] +is_a: GO:0051300 ! spindle pole body organization +created_by: vw +creation_date: 2016-03-14T09:48:42Z + +[Term] +id: GO:1905048 +name: regulation of metallopeptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] +synonym: "regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008237 ! metallopeptidase activity +relationship: regulates GO:0008237 ! metallopeptidase activity +created_by: mm2 +creation_date: 2016-03-15T16:44:27Z + +[Term] +id: GO:1905049 +name: negative regulation of metallopeptidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] +synonym: "down regulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "down regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "downregulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metallopeptidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "inhibition of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:1905048 ! regulation of metallopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008237 ! metallopeptidase activity +relationship: negatively_regulates GO:0008237 ! metallopeptidase activity +created_by: mm2 +creation_date: 2016-03-15T16:44:37Z + +[Term] +id: GO:1905050 +name: positive regulation of metallopeptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] +synonym: "activation of metallopeptidase activity" NARROW [GOC:TermGenie] +synonym: "activation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "activation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "up regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of metalloproteinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of metallopeptidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of metalloprotease activity" NARROW [GOC:TermGenie] +synonym: "upregulation of metalloproteinase activity" NARROW [GOC:TermGenie] +is_a: GO:0010952 ! positive regulation of peptidase activity +is_a: GO:1905048 ! regulation of metallopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008237 ! metallopeptidase activity +relationship: positively_regulates GO:0008237 ! metallopeptidase activity +created_by: mm2 +creation_date: 2016-03-15T16:44:46Z + +[Term] +id: GO:1905051 +name: regulation of base-excision repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of base-excision repair." [GO_REF:0000058, GOC:ah, GOC:TermGenie, PMID:18973764] +synonym: "regulation of BER" EXACT [GOC:TermGenie] +is_a: GO:0006282 ! regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006284 ! base-excision repair +relationship: regulates GO:0006284 ! base-excision repair +created_by: ah +creation_date: 2016-03-16T10:52:00Z + +[Term] +id: GO:1905052 +name: negative regulation of base-excision repair +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair." [GO_REF:0000058, GOC:ah, GOC:TermGenie, PMID:18973764] +synonym: "down regulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "down regulation of BER" EXACT [GOC:TermGenie] +synonym: "down-regulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of BER" EXACT [GOC:TermGenie] +synonym: "downregulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "downregulation of BER" EXACT [GOC:TermGenie] +synonym: "inhibition of base-excision repair" NARROW [GOC:TermGenie] +synonym: "inhibition of BER" NARROW [GOC:TermGenie] +synonym: "negative regulation of BER" EXACT [GOC:TermGenie] +is_a: GO:0045738 ! negative regulation of DNA repair +is_a: GO:1905051 ! regulation of base-excision repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006284 ! base-excision repair +relationship: negatively_regulates GO:0006284 ! base-excision repair +created_by: ah +creation_date: 2016-03-16T10:52:09Z + +[Term] +id: GO:1905053 +name: positive regulation of base-excision repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of base-excision repair." [GO_REF:0000058, GOC:ah, GOC:TermGenie, PMID:18973764] +synonym: "activation of base-excision repair" NARROW [GOC:TermGenie] +synonym: "activation of BER" NARROW [GOC:TermGenie] +synonym: "positive regulation of BER" EXACT [GOC:TermGenie] +synonym: "up regulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "up regulation of BER" EXACT [GOC:TermGenie] +synonym: "up-regulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of BER" EXACT [GOC:TermGenie] +synonym: "upregulation of base-excision repair" EXACT [GOC:TermGenie] +synonym: "upregulation of BER" EXACT [GOC:TermGenie] +is_a: GO:0045739 ! positive regulation of DNA repair +is_a: GO:1905051 ! regulation of base-excision repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006284 ! base-excision repair +relationship: positively_regulates GO:0006284 ! base-excision repair +created_by: ah +creation_date: 2016-03-16T10:52:18Z + +[Term] +id: GO:1905054 +name: calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:15919193, PMID:23918386] +subset: goslim_synapse +synonym: "calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0048763 ! calcium-induced calcium release activity +intersection_of: GO:0048763 ! calcium-induced calcium release activity +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-17T12:12:53Z + +[Term] +id: GO:1905055 +name: calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:22972962, PMID:23255722] +subset: goslim_synapse +synonym: "calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0015368 ! calcium:cation antiporter activity +intersection_of: GO:0015368 ! calcium:cation antiporter activity +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-17T14:35:35Z + +[Term] +id: GO:1905056 +name: calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium-transporting ATPase activity that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:22972962] +subset: goslim_synapse +synonym: "ATP phosphohydrolase (Ca2+-transporting) involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of presynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "Ca(2+)-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "Ca2+-pumping ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "Ca2+-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium ABC transporter involved in regulation of presynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "calcium efflux ATPase involved in regulation of presynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "calcium transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium-translocating P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "plasma membrane Ca-ATPase involved in regulation of presynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +is_a: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-17T14:35:25Z + +[Term] +id: GO:1905057 +name: voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels +namespace: molecular_function +def: "Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:20734177] +subset: goslim_synapse +synonym: "depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "dihydropyridine-sensitive calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "voltage-dependent calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +is_a: GO:0099511 ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels +intersection_of: GO:0005245 ! voltage-gated calcium channel activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-18T12:31:48Z + +[Term] +id: GO:1905058 +name: calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:23639769] +subset: goslim_synapse +synonym: "calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +is_a: GO:0048763 ! calcium-induced calcium release activity +intersection_of: GO:0048763 ! calcium-induced calcium release activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-18T12:31:59Z + +[Term] +id: GO:1905059 +name: calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium-transporting ATPase activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:20678993] +subset: goslim_synapse +synonym: "ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels" EXACT syngo_official_label [] +synonym: "plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +synonym: "sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration" NARROW [GOC:TermGenie] +is_a: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: GO:0005388 ! calcium transmembrane transporter activity, phosphorylative mechanism +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-18T12:32:08Z + +[Term] +id: GO:1905060 +name: calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration +namespace: molecular_function +def: "Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration." [GO_REF:0000061, GOC:TermGenie, PMID:18024055] +subset: goslim_synapse +synonym: "calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion levels" EXACT syngo_official_label [] +is_a: GO:0015368 ! calcium:cation antiporter activity +intersection_of: GO:0015368 ! calcium:cation antiporter activity +intersection_of: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +relationship: part_of GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration +created_by: dos +creation_date: 2016-03-18T12:32:17Z + +[Term] +id: GO:1905061 +name: negative regulation of cardioblast proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24236097] +synonym: "down regulation of cardioblast proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardioblast proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of cardioblast proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of cardioblast proliferation" NARROW [GOC:TermGenie] +is_a: GO:0003264 ! regulation of cardioblast proliferation +is_a: GO:2000137 ! negative regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003263 ! cardioblast proliferation +relationship: negatively_regulates GO:0003263 ! cardioblast proliferation +created_by: bc +creation_date: 2016-03-21T11:00:13Z + +[Term] +id: GO:1905062 +name: positive regulation of cardioblast proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardioblast proliferation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24236097] +synonym: "activation of cardioblast proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of cardioblast proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardioblast proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of cardioblast proliferation" EXACT [GOC:TermGenie] +is_a: GO:0003264 ! regulation of cardioblast proliferation +is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003263 ! cardioblast proliferation +relationship: positively_regulates GO:0003263 ! cardioblast proliferation +created_by: bc +creation_date: 2016-03-21T11:00:23Z + +[Term] +id: GO:1905063 +name: regulation of vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +synonym: "regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie] +is_a: GO:0051150 ! regulation of smooth muscle cell differentiation +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035886 ! vascular smooth muscle cell differentiation +relationship: regulates GO:0035886 ! vascular smooth muscle cell differentiation +created_by: rph +creation_date: 2016-03-21T11:14:53Z + +[Term] +id: GO:1905064 +name: negative regulation of vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of VSMC differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie] +is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation +is_a: GO:1901343 ! negative regulation of vasculature development +is_a: GO:1905063 ! regulation of vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035886 ! vascular smooth muscle cell differentiation +relationship: negatively_regulates GO:0035886 ! vascular smooth muscle cell differentiation +created_by: rph +creation_date: 2016-03-21T11:15:03Z + +[Term] +id: GO:1905065 +name: positive regulation of vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +synonym: "activation of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of VSMC differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie] +is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation +is_a: GO:1904018 ! positive regulation of vasculature development +is_a: GO:1905063 ! regulation of vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035886 ! vascular smooth muscle cell differentiation +relationship: positively_regulates GO:0035886 ! vascular smooth muscle cell differentiation +created_by: rph +creation_date: 2016-03-21T11:15:13Z + +[Term] +id: GO:1905066 +name: regulation of canonical Wnt signaling pathway involved in heart development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25034767] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +is_a: GO:0003307 ! regulation of Wnt signaling pathway involved in heart development +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +relationship: regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +created_by: bc +creation_date: 2016-03-21T12:46:56Z + +[Term] +id: GO:1905067 +name: negative regulation of canonical Wnt signaling pathway involved in heart development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25034767] +synonym: "down regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signalling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt-activated signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +is_a: GO:0003308 ! negative regulation of Wnt signaling pathway involved in heart development +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:1905066 ! regulation of canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +relationship: negatively_regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +created_by: bc +creation_date: 2016-03-21T12:47:06Z + +[Term] +id: GO:1905068 +name: positive regulation of canonical Wnt signaling pathway involved in heart development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25034767] +synonym: "activation of canonical Wnt receptor signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt receptor signalling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt-activated signaling pathway involved in heart development" NARROW [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt-activated signaling pathway involved in heart development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0090263 ! positive regulation of canonical Wnt signaling pathway +is_a: GO:1905066 ! regulation of canonical Wnt signaling pathway involved in heart development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +relationship: positively_regulates GO:0061316 ! canonical Wnt signaling pathway involved in heart development +created_by: bc +creation_date: 2016-03-21T12:47:15Z + +[Term] +id: GO:1905069 +name: allantois development +namespace: biological_process +def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579] +synonym: "allantoic bud development" RELATED [GOC:TermGenie] +is_a: GO:1903867 ! extraembryonic membrane development +created_by: cls +creation_date: 2016-03-21T15:18:21Z + +[Term] +id: GO:1905070 +name: anterior visceral endoderm cell migration +namespace: biological_process +def: "The orderly movement of an anterior visceral endoderm cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:17078044] +is_a: GO:0016477 ! cell migration +created_by: cls +creation_date: 2016-03-21T15:18:32Z + +[Term] +id: GO:1905071 +name: tight junction disassembly +namespace: biological_process +def: "The disaggregation of an tight junction into its constituent components." [GO_REF:0000079, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "occluding junction disassembly" EXACT [] +is_a: GO:0120193 ! tight junction organization +is_a: GO:0150147 ! cell-cell junction disassembly +created_by: rl +creation_date: 2016-03-23T12:35:08Z + +[Term] +id: GO:1905072 +name: cardiac jelly development +namespace: biological_process +def: "The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure." [GO_REF:0000094, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19703439] +synonym: "heart cardiac jelly development" EXACT [GOC:TermGenie] +is_a: GO:0009888 ! tissue development +created_by: rl +creation_date: 2016-03-23T13:17:59Z + +[Term] +id: GO:1905073 +name: regulation of tight junction disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tight junction disassembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "regulation of occluding junction disassembly" EXACT [GOC:TermGenie] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905071 ! tight junction disassembly +relationship: regulates GO:1905071 ! tight junction disassembly +created_by: rl +creation_date: 2016-03-23T19:32:51Z + +[Term] +id: GO:1905074 +name: negative regulation of tight junction disassembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "down regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "down regulation of tight junction disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of tight junction disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of occluding junction disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of tight junction disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of occluding cell junction disassembly" NARROW [GOC:TermGenie] +synonym: "inhibition of occluding junction disassembly" NARROW [GOC:TermGenie] +synonym: "inhibition of tight junction disassembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of tight junction disassembly" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1905073 ! regulation of tight junction disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905071 ! tight junction disassembly +relationship: negatively_regulates GO:1905071 ! tight junction disassembly +created_by: rl +creation_date: 2016-03-23T19:33:01Z + +[Term] +id: GO:1905075 +name: positive regulation of tight junction disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tight junction disassembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "activation of occluding cell junction disassembly" NARROW [GOC:TermGenie] +synonym: "activation of occluding junction disassembly" NARROW [GOC:TermGenie] +synonym: "activation of tight junction disassembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of occluding junction disassembly" EXACT [GOC:TermGenie] +synonym: "up regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "up regulation of tight junction disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of tight junction disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of occluding cell junction disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of tight junction disassembly" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1905073 ! regulation of tight junction disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905071 ! tight junction disassembly +relationship: positively_regulates GO:1905071 ! tight junction disassembly +created_by: rl +creation_date: 2016-03-23T19:33:10Z + +[Term] +id: GO:1905076 +name: regulation of interleukin-17 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-17 secretion." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:16482511] +comment: An example of this is IL23A in human (Q9NPF7) in PMID:16482511 (inferred from direct assay). +synonym: "regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "regulation of IL17A secretion" EXACT [GOC:TermGenie] +is_a: GO:0032660 ! regulation of interleukin-17 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072615 ! interleukin-17 secretion +relationship: regulates GO:0072615 ! interleukin-17 secretion +created_by: bhm +creation_date: 2016-03-24T15:44:21Z + +[Term] +id: GO:1905077 +name: negative regulation of interleukin-17 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17 secretion." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:16482511] +comment: An example of this is IL23A in human (Q9NPF7) in PMID:16482511 (inferred from direct assay). +synonym: "down regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +synonym: "inhibition of CTLA-8 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of Cytotoxic T-lymphocyte-associated antigen 8 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of IL-17 secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of IL-17A secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of IL17A secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of interleukin-17 secretion" NARROW [GOC:TermGenie] +synonym: "negative regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "negative regulation of IL17A secretion" EXACT [GOC:TermGenie] +is_a: GO:0032700 ! negative regulation of interleukin-17 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:1905076 ! regulation of interleukin-17 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072615 ! interleukin-17 secretion +relationship: negatively_regulates GO:0072615 ! interleukin-17 secretion +created_by: bhm +creation_date: 2016-03-24T15:44:31Z + +[Term] +id: GO:1905078 +name: positive regulation of interleukin-17 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-17 secretion." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:16482511] +comment: An example of this is IL23A in human (Q9NPF7) in PMID:16482511 (inferred from direct assay). +synonym: "activation of CTLA-8 secretion" NARROW [GOC:TermGenie] +synonym: "activation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" NARROW [GOC:TermGenie] +synonym: "activation of IL-17 secretion" NARROW [GOC:TermGenie] +synonym: "activation of IL-17A secretion" NARROW [GOC:TermGenie] +synonym: "activation of IL17A secretion" NARROW [GOC:TermGenie] +synonym: "activation of interleukin-17 secretion" NARROW [GOC:TermGenie] +synonym: "positive regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "positive regulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "up regulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "up-regulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of CTLA-8 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-17 secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IL-17A secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of IL17A secretion" EXACT [GOC:TermGenie] +synonym: "upregulation of interleukin-17 secretion" EXACT [GOC:TermGenie] +is_a: GO:0032740 ! positive regulation of interleukin-17 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:1905076 ! regulation of interleukin-17 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072615 ! interleukin-17 secretion +relationship: positively_regulates GO:0072615 ! interleukin-17 secretion +created_by: bhm +creation_date: 2016-03-24T15:44:40Z + +[Term] +id: GO:1905079 +name: regulation of cerebellar neuron development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cerebellar neuron development." [GO_REF:0000058, GOC:TermGenie, PMID:26609159] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098749 ! cerebellar neuron development +relationship: regulates GO:0098749 ! cerebellar neuron development +created_by: hjd +creation_date: 2016-03-24T19:45:17Z + +[Term] +id: GO:1905080 +name: negative regulation of cerebellar neuron development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development." [GO_REF:0000058, GOC:TermGenie, PMID:26609159] +synonym: "down regulation of cerebellar neuron development" EXACT [GOC:TermGenie] +synonym: "down-regulation of cerebellar neuron development" EXACT [GOC:TermGenie] +synonym: "downregulation of cerebellar neuron development" EXACT [GOC:TermGenie] +synonym: "inhibition of cerebellar neuron development" NARROW [GOC:TermGenie] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:1905079 ! regulation of cerebellar neuron development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098749 ! cerebellar neuron development +relationship: negatively_regulates GO:0098749 ! cerebellar neuron development +created_by: hjd +creation_date: 2016-03-24T19:45:26Z + +[Term] +id: GO:1905081 +name: positive regulation of cerebellar neuron development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cerebellar neuron development." [GO_REF:0000058, GOC:TermGenie, PMID:26609159] +synonym: "activation of cerebellar neuron development" NARROW [GOC:TermGenie] +synonym: "up regulation of cerebellar neuron development" EXACT [GOC:TermGenie] +synonym: "up-regulation of cerebellar neuron development" EXACT [GOC:TermGenie] +synonym: "upregulation of cerebellar neuron development" EXACT [GOC:TermGenie] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:1905079 ! regulation of cerebellar neuron development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098749 ! cerebellar neuron development +relationship: positively_regulates GO:0098749 ! cerebellar neuron development +created_by: hjd +creation_date: 2016-03-24T19:45:35Z + +[Term] +id: GO:1905082 +name: regulation of mitochondrial translational elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial translational elongation." [GO_REF:0000058, GOC:TermGenie, PMID:25738458] +synonym: "regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +is_a: GO:0006448 ! regulation of translational elongation +is_a: GO:0070129 ! regulation of mitochondrial translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070125 ! mitochondrial translational elongation +relationship: regulates GO:0070125 ! mitochondrial translational elongation +created_by: hjd +creation_date: 2016-03-25T17:37:03Z + +[Term] +id: GO:1905083 +name: negative regulation of mitochondrial translational elongation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation." [GO_REF:0000058, GOC:TermGenie, PMID:25738458] +synonym: "down regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "down regulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial translation elongation" NARROW [GOC:TermGenie] +synonym: "inhibition of mitochondrial translational elongation" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +is_a: GO:0045900 ! negative regulation of translational elongation +is_a: GO:0070130 ! negative regulation of mitochondrial translation +is_a: GO:1905082 ! regulation of mitochondrial translational elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070125 ! mitochondrial translational elongation +relationship: negatively_regulates GO:0070125 ! mitochondrial translational elongation +created_by: hjd +creation_date: 2016-03-25T17:37:13Z + +[Term] +id: GO:1905084 +name: positive regulation of mitochondrial translational elongation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation." [GO_REF:0000058, GOC:TermGenie, PMID:25738458] +synonym: "activation of mitochondrial translation elongation" NARROW [GOC:TermGenie] +synonym: "activation of mitochondrial translational elongation" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial translation elongation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial translational elongation" EXACT [GOC:TermGenie] +is_a: GO:0045901 ! positive regulation of translational elongation +is_a: GO:0070131 ! positive regulation of mitochondrial translation +is_a: GO:1905082 ! regulation of mitochondrial translational elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070125 ! mitochondrial translational elongation +relationship: positively_regulates GO:0070125 ! mitochondrial translational elongation +created_by: hjd +creation_date: 2016-03-25T17:37:22Z + +[Term] +id: GO:1905085 +name: regulation of bioluminescence +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of bioluminescence." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:10913092] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008218 ! bioluminescence +relationship: regulates GO:0008218 ! bioluminescence +created_by: rph +creation_date: 2016-03-29T07:51:07Z + +[Term] +id: GO:1905086 +name: negative regulation of bioluminescence +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:10913092] +synonym: "down regulation of bioluminescence" EXACT [GOC:TermGenie] +synonym: "down-regulation of bioluminescence" EXACT [GOC:TermGenie] +synonym: "downregulation of bioluminescence" EXACT [GOC:TermGenie] +synonym: "inhibition of bioluminescence" NARROW [GOC:TermGenie] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:1905085 ! regulation of bioluminescence +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008218 ! bioluminescence +relationship: negatively_regulates GO:0008218 ! bioluminescence +created_by: rph +creation_date: 2016-03-29T07:51:17Z + +[Term] +id: GO:1905087 +name: positive regulation of bioluminescence +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of bioluminescence." [GO_REF:0000058, GOC:BHF, GOC:rph, GOC:TermGenie, PMID:10913092] +synonym: "activation of bioluminescence" NARROW [GOC:TermGenie] +synonym: "up regulation of bioluminescence" EXACT [GOC:TermGenie] +synonym: "up-regulation of bioluminescence" EXACT [GOC:TermGenie] +synonym: "upregulation of bioluminescence" EXACT [GOC:TermGenie] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1905085 ! regulation of bioluminescence +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008218 ! bioluminescence +relationship: positively_regulates GO:0008218 ! bioluminescence +created_by: rph +creation_date: 2016-03-29T07:51:27Z + +[Term] +id: GO:1905088 +name: positive regulation of synaptonemal complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24797370] +synonym: "activation of synaptonemal complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of synaptonemal complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of synaptonemal complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptonemal complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptonemal complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptonemal complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptonemal complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptonemal complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptonemal complex formation" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051984 ! positive regulation of chromosome segregation +is_a: GO:0060903 ! positive regulation of meiosis I +is_a: GO:0090173 ! regulation of synaptonemal complex assembly +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007130 ! synaptonemal complex assembly +relationship: positively_regulates GO:0007130 ! synaptonemal complex assembly +created_by: mec +creation_date: 2016-03-30T08:39:03Z + +[Term] +id: GO:1905089 +name: regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:26942284] +synonym: "regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +synonym: "regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +is_a: GO:0080135 ! regulation of cellular response to stress +is_a: GO:1901524 ! regulation of mitophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +relationship: regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +created_by: pad +creation_date: 2016-03-30T15:34:29Z + +[Term] +id: GO:1905090 +name: negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:26942284] +synonym: "down regulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "down-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "downregulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "inhibition of parkin-mediated mitophagy in response to mitochondrial depolarization" NARROW [GOC:TermGenie] +synonym: "negative regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +synonym: "negative regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905089 ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +relationship: negatively_regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +created_by: pad +creation_date: 2016-03-30T15:34:38Z + +[Term] +id: GO:1905091 +name: positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:26942284] +synonym: "activation of parkin-mediated mitophagy in response to mitochondrial depolarization" NARROW [GOC:TermGenie] +synonym: "positive regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +synonym: "positive regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization" EXACT [] +synonym: "up regulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "up-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +synonym: "upregulation of parkin-mediated mitophagy in response to mitochondrial depolarization" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1901526 ! positive regulation of mitophagy +is_a: GO:1905089 ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +relationship: positively_regulates GO:0061734 ! parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization +created_by: pad +creation_date: 2016-03-30T15:34:47Z + +[Term] +id: GO:1905092 +name: response to diosgenin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus." [GO_REF:0000071, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25765596] +is_a: GO:0036314 ! response to sterol +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1905836 ! response to triterpenoid +created_by: bc +creation_date: 2016-03-31T11:04:28Z + +[Term] +id: GO:1905093 +name: cellular response to diosgenin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus." [GO_REF:0000071, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25765596] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0036315 ! cellular response to sterol +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1905092 ! response to diosgenin +is_a: GO:1905837 ! cellular response to triterpenoid +created_by: bc +creation_date: 2016-03-31T11:04:38Z + +[Term] +id: GO:1905094 +name: regulation of apolipoprotein A-I-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25084135] +synonym: "regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +relationship: regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +created_by: bc +creation_date: 2016-03-31T11:33:48Z + +[Term] +id: GO:1905095 +name: negative regulation of apolipoprotein A-I-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25084135] +synonym: "down regulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of apolipoprotein A-I-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of apolipoprotein A-I-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:1905094 ! regulation of apolipoprotein A-I-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +relationship: negatively_regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +created_by: bc +creation_date: 2016-03-31T11:33:58Z + +[Term] +id: GO:1905096 +name: positive regulation of apolipoprotein A-I-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25084135] +synonym: "activation of apolipoprotein A-I-mediated signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of apolipoprotein A-I-mediated signalling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of apolipoprotein A-I-mediated signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of apolipoprotein A-I-mediated signalling pathway" EXACT [GOC:TermGenie] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:1905094 ! regulation of apolipoprotein A-I-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +relationship: positively_regulates GO:0038027 ! apolipoprotein A-I-mediated signaling pathway +created_by: bc +creation_date: 2016-03-31T11:34:07Z + +[Term] +id: GO:1905097 +name: regulation of guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] +synonym: "regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "regulation of GDS" EXACT [GOC:TermGenie] +synonym: "regulation of GEF" EXACT [GOC:TermGenie] +synonym: "regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +is_a: GO:0050789 ! regulation of biological process +is_a: GO:1904424 ! regulation of GTP binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +relationship: regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +created_by: sl +creation_date: 2016-03-31T16:09:35Z + +[Term] +id: GO:1905098 +name: negative regulation of guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] +synonym: "down regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "down regulation of GDS" EXACT [GOC:TermGenie] +synonym: "down regulation of GEF" EXACT [GOC:TermGenie] +synonym: "down regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "down regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "down regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "down-regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of GDS" EXACT [GOC:TermGenie] +synonym: "down-regulation of GEF" EXACT [GOC:TermGenie] +synonym: "down-regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "down-regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "downregulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "downregulation of GDS" EXACT [GOC:TermGenie] +synonym: "downregulation of GEF" EXACT [GOC:TermGenie] +synonym: "downregulation of GNRP" NARROW [GOC:TermGenie] +synonym: "downregulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "inhibition of GDP-dissociation stimulator activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GDS" NARROW [GOC:TermGenie] +synonym: "inhibition of GEF" NARROW [GOC:TermGenie] +synonym: "inhibition of GNRP" NARROW [GOC:TermGenie] +synonym: "inhibition of guanyl-nucleotide exchange factor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of guanyl-nucleotide release factor activity" NARROW [GOC:TermGenie] +synonym: "inhibition of guanyl-nucleotide releasing factor" NARROW [GOC:TermGenie] +synonym: "negative regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of GDS" EXACT [GOC:TermGenie] +synonym: "negative regulation of GEF" EXACT [GOC:TermGenie] +synonym: "negative regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "negative regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +relationship: negatively_regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +created_by: sl +creation_date: 2016-03-31T16:09:45Z + +[Term] +id: GO:1905099 +name: positive regulation of guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] +synonym: "activation of GDP-dissociation stimulator activity" NARROW [GOC:TermGenie] +synonym: "activation of GDS" NARROW [GOC:TermGenie] +synonym: "activation of GEF" NARROW [GOC:TermGenie] +synonym: "activation of GNRP" NARROW [GOC:TermGenie] +synonym: "activation of guanyl-nucleotide exchange factor activity" NARROW [GOC:TermGenie] +synonym: "activation of guanyl-nucleotide release factor activity" NARROW [GOC:TermGenie] +synonym: "activation of guanyl-nucleotide releasing factor" NARROW [GOC:TermGenie] +synonym: "positive regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of GDS" EXACT [GOC:TermGenie] +synonym: "positive regulation of GEF" EXACT [GOC:TermGenie] +synonym: "positive regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "positive regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "up regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "up regulation of GDS" EXACT [GOC:TermGenie] +synonym: "up regulation of GEF" EXACT [GOC:TermGenie] +synonym: "up regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "up regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "up regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "up-regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of GDS" EXACT [GOC:TermGenie] +synonym: "up-regulation of GEF" EXACT [GOC:TermGenie] +synonym: "up-regulation of GNRP" NARROW [GOC:TermGenie] +synonym: "up-regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +synonym: "upregulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] +synonym: "upregulation of GDS" EXACT [GOC:TermGenie] +synonym: "upregulation of GEF" EXACT [GOC:TermGenie] +synonym: "upregulation of GNRP" NARROW [GOC:TermGenie] +synonym: "upregulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1904426 ! positive regulation of GTP binding +is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +relationship: positively_regulates GO:0005085 ! guanyl-nucleotide exchange factor activity +created_by: sl +creation_date: 2016-03-31T16:09:54Z + +[Term] +id: GO:1905100 +name: regulation of apoptosome assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptosome assembly." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:26265044] +synonym: "regulation of apoptosome formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097314 ! apoptosome assembly +relationship: regulates GO:0097314 ! apoptosome assembly +created_by: bc +creation_date: 2016-04-04T08:57:42Z + +[Term] +id: GO:1905101 +name: negative regulation of apoptosome assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:26265044] +synonym: "down regulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "inhibition of apoptosome assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of apoptosome formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of apoptosome formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1905100 ! regulation of apoptosome assembly +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097314 ! apoptosome assembly +relationship: negatively_regulates GO:0097314 ! apoptosome assembly +created_by: bc +creation_date: 2016-04-04T08:57:51Z + +[Term] +id: GO:1905102 +name: positive regulation of apoptosome assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptosome assembly." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:26265044] +synonym: "activation of apoptosome assembly" NARROW [GOC:TermGenie] +synonym: "activation of apoptosome formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of apoptosome formation" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptosome assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of apoptosome formation" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1905100 ! regulation of apoptosome assembly +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097314 ! apoptosome assembly +relationship: positively_regulates GO:0097314 ! apoptosome assembly +created_by: bc +creation_date: 2016-04-04T08:57:59Z + +[Term] +id: GO:1905103 +name: integral component of lysosomal membrane +namespace: cellular_component +def: "The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GO_REF:0000064, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26134396] +synonym: "integral component of lysosome membrane" EXACT [GOC:bf] +synonym: "integral to lysosomal membrane" NARROW [] +is_a: GO:0031166 ! integral component of vacuolar membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0005765 ! lysosomal membrane +relationship: part_of GO:0005765 ! lysosomal membrane +created_by: bf +creation_date: 2016-04-04T10:29:16Z + +[Term] +id: GO:1905104 +name: obsolete response to ouabain +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23643758] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2016-04-04T19:08:07Z + +[Term] +id: GO:1905105 +name: obsolete cellular response to ouabain +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23643758] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2016-04-04T19:08:16Z + +[Term] +id: GO:1905106 +name: obsolete response to Dizocilpine +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20064280] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2016-04-04T20:26:52Z + +[Term] +id: GO:1905107 +name: obsolete cellular response to Dizocilpine +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:20064280] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2016-04-04T20:27:01Z + +[Term] +id: GO:1905108 +name: guanosine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with guanosine." [GO_REF:0000067, GOC:TermGenie, PMID:26007660] +is_a: GO:0032550 ! purine ribonucleoside binding +created_by: al +creation_date: 2016-04-05T08:30:47Z + +[Term] +id: GO:1905109 +name: regulation of pulmonary blood vessel remodeling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +is_a: GO:0060312 ! regulation of blood vessel remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0101010 ! pulmonary blood vessel remodeling +relationship: regulates GO:0101010 ! pulmonary blood vessel remodeling +created_by: bc +creation_date: 2016-04-06T13:07:24Z + +[Term] +id: GO:1905110 +name: negative regulation of pulmonary blood vessel remodeling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +synonym: "down regulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +synonym: "down-regulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +synonym: "downregulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +synonym: "inhibition of pulmonary blood vessel remodeling" NARROW [GOC:TermGenie] +is_a: GO:0060313 ! negative regulation of blood vessel remodeling +is_a: GO:1905109 ! regulation of pulmonary blood vessel remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0101010 ! pulmonary blood vessel remodeling +relationship: negatively_regulates GO:0101010 ! pulmonary blood vessel remodeling +created_by: bc +creation_date: 2016-04-06T13:07:33Z + +[Term] +id: GO:1905111 +name: positive regulation of pulmonary blood vessel remodeling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +synonym: "activation of pulmonary blood vessel remodeling" NARROW [GOC:TermGenie] +synonym: "up regulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +synonym: "up-regulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +synonym: "upregulation of pulmonary blood vessel remodeling" EXACT [GOC:TermGenie] +is_a: GO:1905109 ! regulation of pulmonary blood vessel remodeling +is_a: GO:2000504 ! positive regulation of blood vessel remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0101010 ! pulmonary blood vessel remodeling +relationship: positively_regulates GO:0101010 ! pulmonary blood vessel remodeling +created_by: bc +creation_date: 2016-04-06T13:07:42Z + +[Term] +id: GO:1905112 +name: obsolete regulation of centromere clustering at the mitotic nuclear envelope +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope." [GO_REF:0000058, GOC:TermGenie, PMID:22375062] +comment: This term was obsoleted because it represented a phenotype. +synonym: "regulation of centromere clustering at the nuclear periphery" EXACT [GOC:TermGenie] +synonym: "regulation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "regulation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "regulation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "regulation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "regulation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "regulation of rabl configuration" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-04-06T16:25:41Z + +[Term] +id: GO:1905113 +name: obsolete positive regulation of centromere clustering at the mitotic nuclear envelope +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope." [GO_REF:0000058, GOC:TermGenie, PMID:22375062] +comment: This term was obsoleted because it represented a phenotype. +synonym: "activation of centromere clustering at the nuclear envelope" NARROW [GOC:TermGenie] +synonym: "activation of centromere clustering at the nuclear periphery" NARROW [GOC:TermGenie] +synonym: "activation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "activation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "activation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "activation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "activation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "activation of rabl configuration" RELATED [GOC:TermGenie] +synonym: "positive regulation of centromere clustering at the nuclear periphery" EXACT [GOC:TermGenie] +synonym: "positive regulation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "positive regulation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "positive regulation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "positive regulation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "positive regulation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "positive regulation of rabl configuration" RELATED [GOC:TermGenie] +synonym: "up regulation of centromere clustering at the nuclear envelope" EXACT [GOC:TermGenie] +synonym: "up regulation of centromere clustering at the nuclear periphery" EXACT [GOC:TermGenie] +synonym: "up regulation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "up regulation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "up regulation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "up regulation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "up regulation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "up regulation of rabl configuration" RELATED [GOC:TermGenie] +synonym: "up-regulation of centromere clustering at the nuclear envelope" EXACT [GOC:TermGenie] +synonym: "up-regulation of centromere clustering at the nuclear periphery" EXACT [GOC:TermGenie] +synonym: "up-regulation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "up-regulation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "up-regulation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "up-regulation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "up-regulation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "up-regulation of rabl configuration" RELATED [GOC:TermGenie] +synonym: "upregulation of centromere clustering at the nuclear envelope" EXACT [GOC:TermGenie] +synonym: "upregulation of centromere clustering at the nuclear periphery" EXACT [GOC:TermGenie] +synonym: "upregulation of centromere-SPB clustering" RELATED [GOC:TermGenie] +synonym: "upregulation of kinetochore clustering at SPB" RELATED [GOC:TermGenie] +synonym: "upregulation of kinetochore clustering at spindle pole body" RELATED [GOC:TermGenie] +synonym: "upregulation of kinetochore clustering at the old mitotic spindle pole body" RELATED [GOC:TermGenie] +synonym: "upregulation of kinetochore localization at spindle pole body" RELATED [GOC:TermGenie] +synonym: "upregulation of rabl configuration" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-04-06T16:25:49Z + +[Term] +id: GO:1905114 +name: cell surface receptor signaling pathway involved in cell-cell signaling +namespace: biological_process +def: "Any cell surface receptor signaling pathway that is involved in cell-cell signaling." [GO_REF:0000060, GOC:TermGenie, ISBN:0-7167-3051-0] +synonym: "cell surface receptor linked signal transduction involved in cell-cell signaling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor linked signal transduction involved in cell-cell signalling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor linked signaling pathway involved in cell-cell signaling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor linked signaling pathway involved in cell-cell signalling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor linked signalling pathway involved in cell-cell signaling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor linked signalling pathway involved in cell-cell signalling" EXACT [GOC:TermGenie] +synonym: "cell surface receptor signaling pathway involved in cell-cell signalling" EXACT [GOC:TermGenie] +is_a: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: GO:0007166 ! cell surface receptor signaling pathway +intersection_of: part_of GO:0007267 ! cell-cell signaling +relationship: part_of GO:0007267 ! cell-cell signaling +created_by: dos +creation_date: 2016-04-06T16:59:57Z + +[Term] +id: GO:1905115 +name: regulation of lateral attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore." [GO_REF:0000058, GOC:TermGenie, PMID:22375062] +is_a: GO:1902423 ! regulation of attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099607 ! lateral attachment of mitotic spindle microtubules to kinetochore +relationship: regulates GO:0099607 ! lateral attachment of mitotic spindle microtubules to kinetochore +created_by: al +creation_date: 2016-04-07T14:25:25Z + +[Term] +id: GO:1905116 +name: positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore." [GO_REF:0000058, GOC:TermGenie, PMID:22375062] +synonym: "activation of lateral attachment of mitotic spindle microtubules to kinetochore" NARROW [GOC:TermGenie] +synonym: "up regulation of lateral attachment of mitotic spindle microtubules to kinetochore" EXACT [GOC:TermGenie] +synonym: "up-regulation of lateral attachment of mitotic spindle microtubules to kinetochore" EXACT [GOC:TermGenie] +synonym: "upregulation of lateral attachment of mitotic spindle microtubules to kinetochore" EXACT [GOC:TermGenie] +is_a: GO:1902425 ! positive regulation of attachment of mitotic spindle microtubules to kinetochore +is_a: GO:1905115 ! regulation of lateral attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099607 ! lateral attachment of mitotic spindle microtubules to kinetochore +relationship: positively_regulates GO:0099607 ! lateral attachment of mitotic spindle microtubules to kinetochore +created_by: al +creation_date: 2016-04-07T14:25:34Z + +[Term] +id: GO:1905117 +name: regulation of ribonucleoside-diphosphate reductase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity." [GO_REF:0000059, GOC:bhm, GOC:TermGenie, PMID:24733891] +comment: An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype). +synonym: "regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "regulation of ribonucleotide diphosphate reductase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ribonucleotide reductase activity" BROAD [GOC:TermGenie] +synonym: "regulation of RNR" RELATED [GOC:TermGenie] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061731 ! ribonucleoside-diphosphate reductase activity +relationship: regulates GO:0061731 ! ribonucleoside-diphosphate reductase activity +created_by: bhm +creation_date: 2016-04-08T08:06:17Z + +[Term] +id: GO:1905118 +name: positive regulation of ribonucleoside-diphosphate reductase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity." [GO_REF:0000059, GOC:bhm, GOC:TermGenie, PMID:24733891] +comment: An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype). +synonym: "activation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "activation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "activation of RNR" RELATED [GOC:TermGenie] +synonym: "positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "positive regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "positive regulation of RNR" RELATED [GOC:TermGenie] +synonym: "up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "up regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of RNR" RELATED [GOC:TermGenie] +synonym: "up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "up-regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of RNR" RELATED [GOC:TermGenie] +synonym: "upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] +synonym: "upregulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of RNR" RELATED [GOC:TermGenie] +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:1905117 ! regulation of ribonucleoside-diphosphate reductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061731 ! ribonucleoside-diphosphate reductase activity +relationship: positively_regulates GO:0061731 ! ribonucleoside-diphosphate reductase activity +created_by: bhm +creation_date: 2016-04-08T08:06:35Z + +[Term] +id: GO:1905119 +name: response to haloperidol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus." [GO_REF:0000071, GOC:dw, GOC:TermGenie, PMID:24751813] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097305 ! response to alcohol +is_a: GO:0097332 ! response to antipsychotic drug +is_a: GO:1901654 ! response to ketone +created_by: dw +creation_date: 2016-04-08T12:36:39Z + +[Term] +id: GO:1905120 +name: cellular response to haloperidol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus." [GO_REF:0000071, GOC:dw, GOC:TermGenie, PMID:24751813] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:0097306 ! cellular response to alcohol +is_a: GO:1901655 ! cellular response to ketone +is_a: GO:1905119 ! response to haloperidol +created_by: dw +creation_date: 2016-04-08T12:36:47Z + +[Term] +id: GO:1905121 +name: microtubule sliding involved in mitotic spindle elongation +namespace: biological_process +def: "Any microtubule sliding that is involved in mitotic spindle elongation." [GO_REF:0000060, GOC:TermGenie, GOC:vw, PMID:19686686] +synonym: "microtubule sliding involved in spindle elongation during mitosis" EXACT [GOC:TermGenie] +synonym: "microtubule translocation involved in mitotic spindle elongation" EXACT [GOC:TermGenie] +synonym: "microtubule translocation involved in spindle elongation during mitosis" EXACT [GOC:TermGenie] +is_a: GO:0051012 ! microtubule sliding +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051012 ! microtubule sliding +intersection_of: part_of GO:0000022 ! mitotic spindle elongation +relationship: part_of GO:0000022 ! mitotic spindle elongation +created_by: pr +creation_date: 2016-04-08T15:06:14Z + +[Term] +id: GO:1905123 +name: regulation of glucosylceramidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucosylceramidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24334770] +synonym: "regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of GCase activity" EXACT [PMID:24334770] +synonym: "regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004348 ! glucosylceramidase activity +relationship: regulates GO:0004348 ! glucosylceramidase activity +created_by: bf +creation_date: 2016-04-11T15:44:26Z + +[Term] +id: GO:1905124 +name: negative regulation of glucosylceramidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of acid beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-D-glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of beta-glucosylceramidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ceramide glucosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of GlcCer-beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucosphingosine glucosylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucosylceramidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucosylcerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucosylsphingosine beta-D-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glucosylsphingosine beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of psychosine hydrolase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of GCase activity" EXACT [PMID:24334770] +synonym: "negative regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:1905123 ! regulation of glucosylceramidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004348 ! glucosylceramidase activity +relationship: negatively_regulates GO:0004348 ! glucosylceramidase activity +created_by: bf +creation_date: 2016-04-11T15:44:35Z + +[Term] +id: GO:1905125 +name: positive regulation of glucosylceramidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of acid beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-D-glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of beta-glucosylceramidase activity" NARROW [GOC:TermGenie] +synonym: "activation of ceramide glucosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of D-glucosyl-N-acylsphingosine glucohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of GlcCer-beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucocerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucosphingosine glucosylhydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucosylceramidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucosylcerebrosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucosylsphingosine beta-D-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of glucosylsphingosine beta-glucosidase activity" NARROW [GOC:TermGenie] +synonym: "activation of psychosine hydrolase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of GCase activity" EXACT [PMID:24334770] +synonym: "positive regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucosylceramidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1905123 ! regulation of glucosylceramidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004348 ! glucosylceramidase activity +relationship: positively_regulates GO:0004348 ! glucosylceramidase activity +created_by: bf +creation_date: 2016-04-11T15:44:43Z + +[Term] +id: GO:1905126 +name: regulation of axo-dendritic protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] +synonym: "regulation of axonal protein transport" NARROW [GOC:TermGenie] +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0060632 ! regulation of microtubule-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099640 ! axo-dendritic protein transport +relationship: regulates GO:0099640 ! axo-dendritic protein transport +created_by: sl +creation_date: 2016-04-11T20:38:31Z + +[Term] +id: GO:1905127 +name: negative regulation of axo-dendritic protein transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] +synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "down regulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "downregulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "inhibition of axo-dendritic protein transport" NARROW [GOC:TermGenie] +synonym: "inhibition of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of axonal protein transport" NARROW [GOC:TermGenie] +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1905126 ! regulation of axo-dendritic protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0099640 ! axo-dendritic protein transport +relationship: negatively_regulates GO:0099640 ! axo-dendritic protein transport +created_by: sl +creation_date: 2016-04-11T20:38:40Z + +[Term] +id: GO:1905128 +name: positive regulation of axo-dendritic protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] +synonym: "activation of axo-dendritic protein transport" NARROW [GOC:TermGenie] +synonym: "activation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "up regulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of axonal protein transport" NARROW [GOC:TermGenie] +synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] +synonym: "upregulation of axonal protein transport" NARROW [GOC:TermGenie] +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1905126 ! regulation of axo-dendritic protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099640 ! axo-dendritic protein transport +relationship: positively_regulates GO:0099640 ! axo-dendritic protein transport +created_by: sl +creation_date: 2016-04-11T20:38:48Z + +[Term] +id: GO:1905129 +name: endocannabinoid signaling pathway involved in trans-synaptic signaling +namespace: biological_process +def: "Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid." [GO_REF:0000060, GOC:TermGenie, PMID:23040807] +synonym: "endocannabinoid signalling pathway involved in trans-synaptic signaling by endocannabinoid" EXACT [GOC:TermGenie] +is_a: GO:0071926 ! endocannabinoid signaling pathway +intersection_of: GO:0071926 ! endocannabinoid signaling pathway +intersection_of: part_of GO:0099542 ! trans-synaptic signaling by endocannabinoid +relationship: part_of GO:0099542 ! trans-synaptic signaling by endocannabinoid +created_by: dos +creation_date: 2016-04-12T10:45:13Z + +[Term] +id: GO:1905130 +name: carcinine import across plasma membrane +namespace: biological_process +def: "The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:dph, GOC:TermGenie, PMID:26653853, PMID:26713872] +is_a: GO:0042886 ! amide transport +is_a: GO:0045117 ! azole transmembrane transport +is_a: GO:0072337 ! modified amino acid transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +created_by: dph +creation_date: 2016-04-12T15:15:18Z + +[Term] +id: GO:1905131 +name: carcinine transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of carcinine from one side of a membrane to the other." [GO_REF:0000070, GOC:dph, GOC:TermGenie, PMID:26653853, PMID:26713872] +is_a: GO:0042887 ! amide transmembrane transporter activity +is_a: GO:0072349 ! modified amino acid transmembrane transporter activity +is_a: GO:1901474 ! azole transmembrane transporter activity +created_by: dph +creation_date: 2016-04-12T15:18:25Z + +[Term] +id: GO:1905132 +name: regulation of meiotic chromosome separation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic chromosome separation." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:15620645] +synonym: "regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +is_a: GO:0040020 ! regulation of meiotic nuclear division +is_a: GO:1905818 ! regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051307 ! meiotic chromosome separation +relationship: regulates GO:0051307 ! meiotic chromosome separation +created_by: dph +creation_date: 2016-04-12T17:46:29Z + +[Term] +id: GO:1905133 +name: negative regulation of meiotic chromosome separation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:15620645] +synonym: "down regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "down regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "down regulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +synonym: "downregulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +synonym: "inhibition of chromosome separation during meiosis" NARROW [GOC:TermGenie] +synonym: "inhibition of meiotic chromosome resolution" NARROW [GOC:TermGenie] +synonym: "inhibition of meiotic chromosome separation" NARROW [GOC:TermGenie] +synonym: "negative regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +is_a: GO:0045835 ! negative regulation of meiotic nuclear division +is_a: GO:1905132 ! regulation of meiotic chromosome separation +is_a: GO:1905819 ! negative regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051307 ! meiotic chromosome separation +relationship: negatively_regulates GO:0051307 ! meiotic chromosome separation +created_by: dph +creation_date: 2016-04-12T17:46:37Z + +[Term] +id: GO:1905134 +name: positive regulation of meiotic chromosome separation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:15620645] +synonym: "activation of chromosome separation during meiosis" NARROW [GOC:TermGenie] +synonym: "activation of meiotic chromosome resolution" NARROW [GOC:TermGenie] +synonym: "activation of meiotic chromosome separation" NARROW [GOC:TermGenie] +synonym: "positive regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "up regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "up regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "up regulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +synonym: "upregulation of chromosome separation during meiosis" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic chromosome resolution" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic chromosome separation" EXACT [GOC:TermGenie] +is_a: GO:0045836 ! positive regulation of meiotic nuclear division +is_a: GO:1905132 ! regulation of meiotic chromosome separation +is_a: GO:1905820 ! positive regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051307 ! meiotic chromosome separation +relationship: positively_regulates GO:0051307 ! meiotic chromosome separation +created_by: dph +creation_date: 2016-04-12T17:46:45Z + +[Term] +id: GO:1905135 +name: biotin import across plasma membrane +namespace: biological_process +alt_id: GO:0044756 +alt_id: GO:1901689 +def: "The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:12557275] +synonym: "biotin import" RELATED [] +synonym: "biotin import into cell" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015878 ! biotin transport +is_a: GO:0035461 ! vitamin transmembrane transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: jl +creation_date: 2012-12-05T16:30:20Z + +[Term] +id: GO:1905136 +name: dethiobiotin import across plasma membrane +namespace: biological_process +alt_id: GO:0044757 +alt_id: GO:1901690 +def: "The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:12557275] +synonym: "dethiobiotin import" RELATED [] +synonym: "dethiobiotin import into cell" EXACT [] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0042886 ! amide transport +is_a: GO:0098657 ! import into cell +is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: jl +creation_date: 2012-12-06T13:06:28Z + +[Term] +id: GO:1905137 +name: regulation of viral DNA genome packaging via site-specific sequence recognition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition." [GO_REF:0000058, GOC:TermGenie, PMID:24711378] +is_a: GO:1903900 ! regulation of viral life cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +relationship: regulates GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +created_by: pr +creation_date: 2016-04-13T11:37:13Z + +[Term] +id: GO:1905138 +name: positive regulation of viral DNA genome packaging via site-specific sequence recognition +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition." [GO_REF:0000058, GOC:TermGenie, PMID:24711378] +synonym: "activation of viral DNA genome packaging via site-specific sequence recognition" NARROW [GOC:TermGenie] +synonym: "up regulation of viral DNA genome packaging via site-specific sequence recognition" EXACT [GOC:TermGenie] +synonym: "up-regulation of viral DNA genome packaging via site-specific sequence recognition" EXACT [GOC:TermGenie] +synonym: "upregulation of viral DNA genome packaging via site-specific sequence recognition" EXACT [GOC:TermGenie] +is_a: GO:1903902 ! positive regulation of viral life cycle +is_a: GO:1905137 ! regulation of viral DNA genome packaging via site-specific sequence recognition +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +relationship: positively_regulates GO:0098035 ! viral DNA genome packaging via site-specific sequence recognition +created_by: pr +creation_date: 2016-04-13T11:37:22Z + +[Term] +id: GO:1905139 +name: apical ectodermal ridge formation +namespace: biological_process +def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583] +synonym: "AER formation" RELATED [GOC:TermGenie] +synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +relationship: part_of GO:0035107 ! appendage morphogenesis +created_by: dph +creation_date: 2016-04-13T11:46:40Z + +[Term] +id: GO:1905140 +name: regulation of apical ectodermal ridge formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] +synonym: "regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905139 ! apical ectodermal ridge formation +relationship: regulates GO:1905139 ! apical ectodermal ridge formation +created_by: dph +creation_date: 2016-04-13T12:16:40Z + +[Term] +id: GO:1905141 +name: negative regulation of apical ectodermal ridge formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] +synonym: "down regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "down regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "downregulation of AER formation" RELATED [GOC:TermGenie] +synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "downregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "inhibition of AER formation" RELATED [GOC:TermGenie] +synonym: "inhibition of apical ectodermal ridge formation" NARROW [GOC:TermGenie] +synonym: "inhibition of apical epidermal ridge formation" NARROW [GOC:TermGenie] +synonym: "inhibition of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905140 ! regulation of apical ectodermal ridge formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905139 ! apical ectodermal ridge formation +relationship: negatively_regulates GO:1905139 ! apical ectodermal ridge formation +created_by: dph +creation_date: 2016-04-13T12:16:48Z + +[Term] +id: GO:1905142 +name: positive regulation of apical ectodermal ridge formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] +synonym: "activation of AER formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "up regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "up regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of AER formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +synonym: "upregulation of AER formation" RELATED [GOC:TermGenie] +synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] +synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] +synonym: "upregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905140 ! regulation of apical ectodermal ridge formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905139 ! apical ectodermal ridge formation +relationship: positively_regulates GO:1905139 ! apical ectodermal ridge formation +created_by: dph +creation_date: 2016-04-13T12:16:57Z + +[Term] +id: GO:1905143 +name: eukaryotic translation initiation factor 2 complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex." [GO_REF:0000079, GOC:TermGenie, PMID:23775072] +synonym: "eIF-2 assembly" EXACT [GOC:TermGenie] +synonym: "eIF-2 formation" EXACT [GOC:TermGenie] +synonym: "eIF2 assembly" EXACT [GOC:TermGenie] +synonym: "eIF2 formation" EXACT [GOC:TermGenie] +synonym: "eukaryotic translation initiation factor 2 complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: dph +creation_date: 2016-04-14T00:25:51Z + +[Term] +id: GO:1905144 +name: response to acetylcholine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] +is_a: GO:0009725 ! response to hormone +is_a: GO:0042493 ! response to drug +is_a: GO:1901698 ! response to nitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: dos +creation_date: 2016-04-14T08:54:49Z + +[Term] +id: GO:1905145 +name: cellular response to acetylcholine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035690 ! cellular response to drug +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905144 ! response to acetylcholine +created_by: dos +creation_date: 2016-04-14T08:54:58Z + +[Term] +id: GO:1905146 +name: lysosomal protein catabolic process +namespace: biological_process +def: "Any cellular protein catabolic process that takes place in a lysosome." [GO_REF:0000062, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24334770] +comment: Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants. +synonym: "cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "cellular protein catabolic process in lysosome" EXACT [] +synonym: "cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "lysosomal protein catabolism" EXACT [GOC:bf] +synonym: "lysosomal protein degradation" EXACT [GOC:bf] +synonym: "lysosomal proteolysis" RELATED [PMID:24334770] +synonym: "proteolysis within lysosome" RELATED [GOC:bf] +is_a: GO:0007039 ! protein catabolic process in the vacuole +intersection_of: GO:0044257 ! cellular protein catabolic process +intersection_of: occurs_in GO:0005764 ! lysosome +relationship: occurs_in GO:0005764 ! lysosome +created_by: bf +creation_date: 2016-04-14T12:50:34Z + +[Term] +id: GO:1905147 +name: regulation of smooth muscle hypertrophy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +is_a: GO:0014743 ! regulation of muscle hypertrophy +is_a: GO:0043502 ! regulation of muscle adaptation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014895 ! smooth muscle hypertrophy +relationship: regulates GO:0014895 ! smooth muscle hypertrophy +created_by: bc +creation_date: 2016-04-15T12:47:07Z + +[Term] +id: GO:1905148 +name: negative regulation of smooth muscle hypertrophy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "inhibition of smooth muscle hypertrophy" NARROW [GOC:TermGenie] +is_a: GO:0014741 ! negative regulation of muscle hypertrophy +is_a: GO:0014745 ! negative regulation of muscle adaptation +is_a: GO:1905147 ! regulation of smooth muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014895 ! smooth muscle hypertrophy +relationship: negatively_regulates GO:0014895 ! smooth muscle hypertrophy +created_by: bc +creation_date: 2016-04-15T12:47:16Z + +[Term] +id: GO:1905149 +name: positive regulation of smooth muscle hypertrophy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] +synonym: "activation of smooth muscle hypertrophy" NARROW [GOC:TermGenie] +synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] +is_a: GO:0014742 ! positive regulation of muscle hypertrophy +is_a: GO:0014744 ! positive regulation of muscle adaptation +is_a: GO:1905147 ! regulation of smooth muscle hypertrophy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014895 ! smooth muscle hypertrophy +relationship: positively_regulates GO:0014895 ! smooth muscle hypertrophy +created_by: bc +creation_date: 2016-04-15T12:47:24Z + +[Term] +id: GO:1905150 +name: regulation of voltage-gated sodium channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] +synonym: "regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005248 ! voltage-gated sodium channel activity +relationship: regulates GO:0005248 ! voltage-gated sodium channel activity +created_by: sl +creation_date: 2016-04-15T21:47:40Z + +[Term] +id: GO:1905151 +name: negative regulation of voltage-gated sodium channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] +synonym: "down regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "downregulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "inhibition of voltage gated sodium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-dependent sodium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated sodium channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-gated sodium ion channel activity" NARROW [GOC:TermGenie] +synonym: "inhibition of voltage-sensitive sodium channel" NARROW [GOC:TermGenie] +synonym: "negative regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +is_a: GO:1905150 ! regulation of voltage-gated sodium channel activity +is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005248 ! voltage-gated sodium channel activity +relationship: negatively_regulates GO:0005248 ! voltage-gated sodium channel activity +created_by: sl +creation_date: 2016-04-15T21:47:49Z + +[Term] +id: GO:1905152 +name: positive regulation of voltage-gated sodium channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] +synonym: "activation of voltage gated sodium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-dependent sodium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated sodium channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-gated sodium ion channel activity" NARROW [GOC:TermGenie] +synonym: "activation of voltage-sensitive sodium channel" NARROW [GOC:TermGenie] +synonym: "positive regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] +synonym: "upregulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] +is_a: GO:1905150 ! regulation of voltage-gated sodium channel activity +is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005248 ! voltage-gated sodium channel activity +relationship: positively_regulates GO:0005248 ! voltage-gated sodium channel activity +created_by: sl +creation_date: 2016-04-15T21:47:57Z + +[Term] +id: GO:1905153 +name: regulation of membrane invagination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010324 ! membrane invagination +relationship: regulates GO:0010324 ! membrane invagination +created_by: bf +creation_date: 2016-04-18T15:43:54Z + +[Term] +id: GO:1905154 +name: negative regulation of membrane invagination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] +synonym: "down regulation of membrane invagination" EXACT [GOC:TermGenie] +synonym: "down-regulation of membrane invagination" EXACT [GOC:TermGenie] +synonym: "downregulation of membrane invagination" EXACT [GOC:TermGenie] +synonym: "inhibition of membrane invagination" NARROW [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1905153 ! regulation of membrane invagination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010324 ! membrane invagination +relationship: negatively_regulates GO:0010324 ! membrane invagination +created_by: bf +creation_date: 2016-04-18T15:44:04Z + +[Term] +id: GO:1905155 +name: positive regulation of membrane invagination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of membrane invagination" NARROW [GOC:TermGenie] +synonym: "up regulation of membrane invagination" EXACT [GOC:TermGenie] +synonym: "up-regulation of membrane invagination" EXACT [GOC:TermGenie] +synonym: "upregulation of membrane invagination" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1905153 ! regulation of membrane invagination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010324 ! membrane invagination +relationship: positively_regulates GO:0010324 ! membrane invagination +created_by: bf +creation_date: 2016-04-18T15:44:12Z + +[Term] +id: GO:1905156 +name: negative regulation of photosynthesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis." [GO_REF:0000058, GOC:TermGenie, PMID:7592491] +synonym: "down regulation of photosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of photosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of photosynthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of photosynthesis" NARROW [GOC:TermGenie] +is_a: GO:0010109 ! regulation of photosynthesis +is_a: GO:0031324 ! negative regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015979 ! photosynthesis +relationship: negatively_regulates GO:0015979 ! photosynthesis +created_by: tb +creation_date: 2016-04-19T16:12:29Z + +[Term] +id: GO:1905157 +name: positive regulation of photosynthesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of photosynthesis." [GO_REF:0000058, GOC:TermGenie, PMID:7592491] +synonym: "activation of photosynthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of photosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of photosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of photosynthesis" EXACT [GOC:TermGenie] +is_a: GO:0010109 ! regulation of photosynthesis +is_a: GO:0031325 ! positive regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015979 ! photosynthesis +relationship: positively_regulates GO:0015979 ! photosynthesis +created_by: tb +creation_date: 2016-04-19T16:12:39Z + +[Term] +id: GO:1905158 +name: obsolete regulation of Factor XII activation +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation." [GO_REF:0000058, GOC:TermGenie, PMID:617517] +comment: This term was accidentally approved after TermGenie review. It should not have been approved. +synonym: "regulation of Hageman factor activation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: sl +creation_date: 2016-04-19T23:03:25Z + +[Term] +id: GO:1905159 +name: obsolete negative regulation of Factor XII activation +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Factor XII activation." [GO_REF:0000058, GOC:TermGenie, PMID:617517] +comment: This term was accidentally approved after TermGenie review. It should not have been approved. +synonym: "down regulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "down regulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "downregulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "downregulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "inhibition of Factor XII activation" NARROW [GOC:TermGenie] +synonym: "inhibition of Hageman factor activation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Hageman factor activation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: sl +creation_date: 2016-04-19T23:03:34Z + +[Term] +id: GO:1905160 +name: obsolete positive regulation of Factor XII activation +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of Factor XII activation." [GO_REF:0000058, GOC:TermGenie, PMID:617517] +comment: This term was accidentally approved after TermGenie review. It should not have been approved. +synonym: "activation of Factor XII activation" NARROW [GOC:TermGenie] +synonym: "activation of Hageman factor activation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "up regulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "up regulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Hageman factor activation" EXACT [GOC:TermGenie] +synonym: "upregulation of Factor XII activation" EXACT [GOC:TermGenie] +synonym: "upregulation of Hageman factor activation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: sl +creation_date: 2016-04-19T23:03:43Z + +[Term] +id: GO:1905161 +name: protein localization to phagocytic vesicle +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle." [GO_REF:0000087, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23303671] +synonym: "protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "protein localisation to phagosome" EXACT [PMID:23303671] +synonym: "protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "protein recruitment to phagosome" EXACT [PMID:23303671] +is_a: GO:0033365 ! protein localization to organelle +created_by: bf +creation_date: 2016-04-25T15:05:13Z + +[Term] +id: GO:1905162 +name: regulation of phagosome maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phagosome maturation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16908865, PMID:23303671] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090382 ! phagosome maturation +relationship: regulates GO:0090382 ! phagosome maturation +created_by: bf +creation_date: 2016-04-25T16:28:03Z + +[Term] +id: GO:1905163 +name: negative regulation of phagosome maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of phagosome maturation" EXACT [GOC:TermGenie] +synonym: "down-regulation of phagosome maturation" EXACT [GOC:TermGenie] +synonym: "downregulation of phagosome maturation" EXACT [GOC:TermGenie] +synonym: "inhibition of phagosome maturation" NARROW [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1905162 ! regulation of phagosome maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090382 ! phagosome maturation +relationship: negatively_regulates GO:0090382 ! phagosome maturation +created_by: bf +creation_date: 2016-04-25T16:28:11Z + +[Term] +id: GO:1905164 +name: positive regulation of phagosome maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phagosome maturation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of phagosome maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of phagosome maturation" EXACT [GOC:TermGenie] +synonym: "up-regulation of phagosome maturation" EXACT [GOC:TermGenie] +synonym: "upregulation of phagosome maturation" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1905162 ! regulation of phagosome maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090382 ! phagosome maturation +relationship: positively_regulates GO:0090382 ! phagosome maturation +created_by: bf +creation_date: 2016-04-25T16:28:19Z + +[Term] +id: GO:1905165 +name: regulation of lysosomal protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23499937] +synonym: "regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905146 ! lysosomal protein catabolic process +relationship: regulates GO:1905146 ! lysosomal protein catabolic process +created_by: bf +creation_date: 2016-04-26T12:10:01Z + +[Term] +id: GO:1905166 +name: negative regulation of lysosomal protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "down regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "down-regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "downregulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "inhibition of cellular protein breakdown in lysosome" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein catabolic process in lysosome" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein catabolism in lysosome" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular protein degradation in lysosome" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosomal protein catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosomal protein degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "inhibition of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "negative regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "negative regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +is_a: GO:1904351 ! negative regulation of protein catabolic process in the vacuole +is_a: GO:1905165 ! regulation of lysosomal protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905146 ! lysosomal protein catabolic process +relationship: negatively_regulates GO:1905146 ! lysosomal protein catabolic process +created_by: bf +creation_date: 2016-04-26T12:10:10Z + +[Term] +id: GO:1905167 +name: positive regulation of lysosomal protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of cellular protein breakdown in lysosome" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein catabolic process in lysosome" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein catabolism in lysosome" NARROW [GOC:TermGenie] +synonym: "activation of cellular protein degradation in lysosome" NARROW [GOC:TermGenie] +synonym: "activation of lysosomal protein catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of lysosomal protein catabolism" NARROW [GOC:TermGenie] +synonym: "activation of lysosomal protein degradation" NARROW [GOC:TermGenie] +synonym: "activation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "activation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "positive regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "positive regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "positive regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "up regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "up regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "up-regulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "up-regulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +synonym: "upregulation of cellular protein breakdown in lysosome" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein catabolic process in lysosome" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein catabolism in lysosome" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular protein degradation in lysosome" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosomal protein catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosomal protein catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosomal protein degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosomal proteolysis" RELATED [GOC:TermGenie] +synonym: "upregulation of proteolysis within lysosome" RELATED [GOC:TermGenie] +is_a: GO:1904352 ! positive regulation of protein catabolic process in the vacuole +is_a: GO:1905165 ! regulation of lysosomal protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905146 ! lysosomal protein catabolic process +relationship: positively_regulates GO:1905146 ! lysosomal protein catabolic process +created_by: bf +creation_date: 2016-04-26T12:10:19Z + +[Term] +id: GO:1905168 +name: positive regulation of double-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination." [GO_REF:0000058, GOC:TermGenie, PMID:12023299] +synonym: "activation of double-strand break repair via homologous recombination" NARROW [GOC:TermGenie] +synonym: "activation of HDR" NARROW [GOC:TermGenie] +synonym: "activation of homologous recombinational repair" NARROW [GOC:TermGenie] +synonym: "activation of homology-directed repair" NARROW [GOC:TermGenie] +synonym: "activation of HRR" NARROW [GOC:TermGenie] +synonym: "activation of Rad51-dependent recombinational repair" NARROW [GOC:TermGenie] +synonym: "activation of Rhp51-dependent recombinational repair" NARROW [GOC:TermGenie] +synonym: "positive regulation of HDR" EXACT [GOC:TermGenie] +synonym: "positive regulation of homologous recombinational repair" EXACT [GOC:TermGenie] +synonym: "positive regulation of homology-directed repair" EXACT [GOC:TermGenie] +synonym: "positive regulation of HRR" EXACT [GOC:TermGenie] +synonym: "positive regulation of Rad51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "positive regulation of Rhp51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "up regulation of double-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "up regulation of HDR" EXACT [GOC:TermGenie] +synonym: "up regulation of homologous recombinational repair" EXACT [GOC:TermGenie] +synonym: "up regulation of homology-directed repair" EXACT [GOC:TermGenie] +synonym: "up regulation of HRR" EXACT [GOC:TermGenie] +synonym: "up regulation of Rad51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "up regulation of Rhp51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of double-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "up-regulation of HDR" EXACT [GOC:TermGenie] +synonym: "up-regulation of homologous recombinational repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of homology-directed repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of HRR" EXACT [GOC:TermGenie] +synonym: "up-regulation of Rad51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of Rhp51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "upregulation of double-strand break repair via homologous recombination" EXACT [GOC:TermGenie] +synonym: "upregulation of HDR" EXACT [GOC:TermGenie] +synonym: "upregulation of homologous recombinational repair" EXACT [GOC:TermGenie] +synonym: "upregulation of homology-directed repair" EXACT [GOC:TermGenie] +synonym: "upregulation of HRR" EXACT [GOC:TermGenie] +synonym: "upregulation of Rad51-dependent recombinational repair" EXACT [GOC:TermGenie] +synonym: "upregulation of Rhp51-dependent recombinational repair" EXACT [GOC:TermGenie] +is_a: GO:0010569 ! regulation of double-strand break repair via homologous recombination +is_a: GO:0045911 ! positive regulation of DNA recombination +is_a: GO:2000781 ! positive regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000724 ! double-strand break repair via homologous recombination +relationship: positively_regulates GO:0000724 ! double-strand break repair via homologous recombination +created_by: mah +creation_date: 2016-04-27T12:48:47Z + +[Term] +id: GO:1905169 +name: regulation of protein localization to phagocytic vesicle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905161 ! protein localization to phagocytic vesicle +relationship: regulates GO:1905161 ! protein localization to phagocytic vesicle +created_by: bf +creation_date: 2016-05-02T18:38:13Z + +[Term] +id: GO:1905170 +name: negative regulation of protein localization to phagocytic vesicle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "downregulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to phagosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "inhibition of protein recruitment to phagosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905169 ! regulation of protein localization to phagocytic vesicle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905161 ! protein localization to phagocytic vesicle +relationship: negatively_regulates GO:1905161 ! protein localization to phagocytic vesicle +created_by: bf +creation_date: 2016-05-02T18:38:22Z + +[Term] +id: GO:1905171 +name: positive regulation of protein localization to phagocytic vesicle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23303671] +synonym: "activation of protein localisation in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to phagosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to phagocytic vesicle" NARROW [GOC:TermGenie] +synonym: "activation of protein recruitment to phagosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to phagosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to phagocytic vesicle" EXACT [GOC:TermGenie] +synonym: "upregulation of protein recruitment to phagosome" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905169 ! regulation of protein localization to phagocytic vesicle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905161 ! protein localization to phagocytic vesicle +relationship: positively_regulates GO:1905161 ! protein localization to phagocytic vesicle +created_by: bf +creation_date: 2016-05-02T18:38:30Z + +[Term] +id: GO:1905172 +name: RISC complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a RISC complex." [GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24882364] +synonym: "RNA-induced silencing complex binding" EXACT [GOC:TermGenie] +is_a: GO:0043021 ! ribonucleoprotein complex binding +created_by: bf +creation_date: 2016-05-02T19:27:02Z + +[Term] +id: GO:1905173 +name: eukaryotic translation initiation factor 2B complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex." [GO_REF:0000079, GOC:TermGenie, PMID:27023709] +synonym: "eIF-2B assembly" EXACT [GOC:TermGenie] +synonym: "eIF-2B formation" EXACT [GOC:TermGenie] +synonym: "eif2B assembly" EXACT [GOC:TermGenie] +synonym: "eif2B formation" EXACT [GOC:TermGenie] +synonym: "eukaryotic translation initiation factor 2B complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2016-05-03T11:00:21Z + +[Term] +id: GO:1905174 +name: regulation of vascular smooth muscle cell dedifferentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:1900239 ! regulation of phenotypic switching +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +relationship: regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +created_by: rph +creation_date: 2016-05-03T12:31:57Z + +[Term] +id: GO:1905175 +name: negative regulation of vascular smooth muscle cell dedifferentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +synonym: "down regulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell dedifferentiation" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1900240 ! negative regulation of phenotypic switching +is_a: GO:1905174 ! regulation of vascular smooth muscle cell dedifferentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +relationship: negatively_regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +created_by: rph +creation_date: 2016-05-03T12:32:05Z + +[Term] +id: GO:1905176 +name: positive regulation of vascular smooth muscle cell dedifferentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] +synonym: "activation of vascular smooth muscle cell dedifferentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell dedifferentiation" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1900241 ! positive regulation of phenotypic switching +is_a: GO:1905174 ! regulation of vascular smooth muscle cell dedifferentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +relationship: positively_regulates GO:1990936 ! vascular smooth muscle cell dedifferentiation +created_by: rph +creation_date: 2016-05-03T12:32:13Z + +[Term] +id: GO:1905177 +name: tracheary element differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element." [GO_REF:0000086, GOC:TermGenie, PMID:20659276] +is_a: GO:0030154 ! cell differentiation +created_by: tb +creation_date: 2016-05-04T22:14:33Z + +[Term] +id: GO:1905178 +name: regulation of cardiac muscle tissue regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23222520] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:0061041 ! regulation of wound healing +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061026 ! cardiac muscle tissue regeneration +relationship: regulates GO:0061026 ! cardiac muscle tissue regeneration +created_by: rph +creation_date: 2016-05-05T11:30:48Z + +[Term] +id: GO:1905179 +name: negative regulation of cardiac muscle tissue regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23222520] +synonym: "down regulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac muscle tissue regeneration" NARROW [GOC:TermGenie] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:1905178 ! regulation of cardiac muscle tissue regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061026 ! cardiac muscle tissue regeneration +relationship: negatively_regulates GO:0061026 ! cardiac muscle tissue regeneration +created_by: rph +creation_date: 2016-05-05T11:30:57Z + +[Term] +id: GO:1905180 +name: positive regulation of cardiac muscle tissue regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23222520] +synonym: "activation of cardiac muscle tissue regeneration" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac muscle tissue regeneration" EXACT [GOC:TermGenie] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:1905178 ! regulation of cardiac muscle tissue regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061026 ! cardiac muscle tissue regeneration +relationship: positively_regulates GO:0061026 ! cardiac muscle tissue regeneration +created_by: rph +creation_date: 2016-05-05T11:31:06Z + +[Term] +id: GO:1905181 +name: regulation of urease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of urease activity." [GO_REF:0000059, GOC:TermGenie, PMID:16244137] +synonym: "regulation of urea amidohydrolase activity" EXACT [GOC:TermGenie] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009039 ! urease activity +relationship: regulates GO:0009039 ! urease activity +created_by: tb +creation_date: 2016-05-09T23:15:54Z + +[Term] +id: GO:1905182 +name: positive regulation of urease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of urease activity." [GO_REF:0000059, GOC:TermGenie, PMID:16244137] +synonym: "activation of urea amidohydrolase activity" NARROW [GOC:TermGenie] +synonym: "activation of urease activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of urea amidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of urea amidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of urease activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of urea amidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of urease activity" EXACT [GOC:TermGenie] +synonym: "upregulation of urea amidohydrolase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of urease activity" EXACT [GOC:TermGenie] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:1905181 ! regulation of urease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009039 ! urease activity +relationship: positively_regulates GO:0009039 ! urease activity +created_by: tb +creation_date: 2016-05-09T23:16:03Z + +[Term] +id: GO:1905183 +name: negative regulation of protein serine/threonine phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:16950131] +synonym: "down regulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of protein serine/threonine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of serine/threonine specific protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0032515 ! negative regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004722 ! protein serine/threonine phosphatase activity +relationship: negatively_regulates GO:0004722 ! protein serine/threonine phosphatase activity +created_by: mah +creation_date: 2016-05-10T15:28:04Z + +[Term] +id: GO:1905184 +name: positive regulation of protein serine/threonine phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity." [GO_REF:0000059, GOC:TermGenie, PMID:16950131] +synonym: "activation of protein serine/threonine phosphatase activity" NARROW [GOC:TermGenie] +synonym: "activation of serine/threonine specific protein phosphatase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of protein serine/threonine phosphatase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of serine/threonine specific protein phosphatase activity" EXACT [GOC:TermGenie] +is_a: GO:0032516 ! positive regulation of phosphoprotein phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004722 ! protein serine/threonine phosphatase activity +relationship: positively_regulates GO:0004722 ! protein serine/threonine phosphatase activity +created_by: mah +creation_date: 2016-05-10T15:28:13Z + +[Term] +id: GO:1905185 +name: microtubule sliding involved in mitotic metaphase chromosome recapture +namespace: biological_process +def: "Any microtubule sliding that is involved in mitotic metaphase chromosome recapture." [GO_REF:0000060, GOC:TermGenie, PMID:18256284] +synonym: "microtubule sliding involved in kinetochore retrieval" EXACT [GOC:TermGenie] +synonym: "microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body" EXACT [GOC:TermGenie] +synonym: "microtubule sliding involved in sister kinetochore recapture" EXACT [GOC:TermGenie] +is_a: GO:0051012 ! microtubule sliding +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:0051012 ! microtubule sliding +intersection_of: part_of GO:1990942 ! mitotic metaphase chromosome recapture +relationship: part_of GO:1990942 ! mitotic metaphase chromosome recapture +created_by: vw +creation_date: 2016-05-10T16:08:25Z + +[Term] +id: GO:1905186 +name: regulation of metaphase/anaphase transition of meiosis I +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +synonym: "regulation of first meiotic metaphase/anaphase transition" RELATED [GOC:TermGenie] +synonym: "regulation of meiosis I metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1902102 ! regulation of metaphase/anaphase transition of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +relationship: regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +created_by: vw +creation_date: 2016-05-10T16:32:03Z + +[Term] +id: GO:1905187 +name: negative regulation of metaphase/anaphase transition of meiosis I +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +is_a: GO:1902103 ! negative regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905186 ! regulation of metaphase/anaphase transition of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +relationship: negatively_regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +created_by: vw +creation_date: 2016-05-10T16:32:11Z + +[Term] +id: GO:1905188 +name: positive regulation of metaphase/anaphase transition of meiosis I +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +synonym: "positive regulation of meiosis I metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1902104 ! positive regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905186 ! regulation of metaphase/anaphase transition of meiosis I +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +relationship: positively_regulates GO:1990949 ! metaphase/anaphase transition of meiosis I +created_by: vw +creation_date: 2016-05-10T16:32:19Z + +[Term] +id: GO:1905189 +name: regulation of metaphase/anaphase transition of meiosis II +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +synonym: "regulation of meiosis II metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1902102 ! regulation of metaphase/anaphase transition of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +relationship: regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +created_by: vw +creation_date: 2016-05-10T16:46:49Z + +[Term] +id: GO:1905190 +name: negative regulation of metaphase/anaphase transition of meiosis II +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +synonym: "negative regulation of meiosis II metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1902103 ! negative regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905189 ! regulation of metaphase/anaphase transition of meiosis II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +relationship: negatively_regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +created_by: vw +creation_date: 2016-05-10T16:46:57Z + +[Term] +id: GO:1905191 +name: positive regulation of metaphase/anaphase transition of meiosis II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II." [GO_REF:0000058, GOC:TermGenie, PMID:21389117] +synonym: "positive regulation of meiosis II metaphase/anaphase transition" EXACT [GOC:TermGenie] +is_a: GO:1902104 ! positive regulation of metaphase/anaphase transition of meiotic cell cycle +is_a: GO:1905189 ! regulation of metaphase/anaphase transition of meiosis II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +relationship: positively_regulates GO:1990950 ! metaphase/anaphase transition of meiosis II +created_by: vw +creation_date: 2016-05-10T16:47:05Z + +[Term] +id: GO:1905192 +name: regulation of chloroplast fission +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chloroplast fission." [GO_REF:0000058, GOC:TermGenie, PMID:26862170] +comment: Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments. +synonym: "regulation of chloroplast division" EXACT [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010020 ! chloroplast fission +relationship: regulates GO:0010020 ! chloroplast fission +created_by: lr +creation_date: 2016-05-10T19:07:34Z + +[Term] +id: GO:1905193 +name: negative regulation of chloroplast fission +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission." [GO_REF:0000058, GOC:TermGenie, PMID:26862170] +comment: Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments. +synonym: "down regulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "down regulation of chloroplast fission" EXACT [GOC:TermGenie] +synonym: "down-regulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "down-regulation of chloroplast fission" EXACT [GOC:TermGenie] +synonym: "downregulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "downregulation of chloroplast fission" EXACT [GOC:TermGenie] +synonym: "inhibition of chloroplast division" NARROW [GOC:TermGenie] +synonym: "inhibition of chloroplast fission" NARROW [GOC:TermGenie] +synonym: "negative regulation of chloroplast division" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1905192 ! regulation of chloroplast fission +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010020 ! chloroplast fission +relationship: negatively_regulates GO:0010020 ! chloroplast fission +created_by: lr +creation_date: 2016-05-10T19:07:43Z + +[Term] +id: GO:1905194 +name: positive regulation of chloroplast fission +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chloroplast fission." [GO_REF:0000058, GOC:TermGenie, PMID:26862170] +comment: Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments. +synonym: "activation of chloroplast division" NARROW [GOC:TermGenie] +synonym: "activation of chloroplast fission" NARROW [GOC:TermGenie] +synonym: "positive regulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "up regulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "up regulation of chloroplast fission" EXACT [GOC:TermGenie] +synonym: "up-regulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "up-regulation of chloroplast fission" EXACT [GOC:TermGenie] +synonym: "upregulation of chloroplast division" EXACT [GOC:TermGenie] +synonym: "upregulation of chloroplast fission" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1905192 ! regulation of chloroplast fission +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010020 ! chloroplast fission +relationship: positively_regulates GO:0010020 ! chloroplast fission +created_by: lr +creation_date: 2016-05-10T19:07:51Z + +[Term] +id: GO:1905195 +name: obsolete regulation of ATPase activity, uncoupled +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled." [GO_REF:0000059, GOC:TermGenie, PMID:26545917] +comment: The reason for obsoletion is that the there is no convincing example of a protein with this function. +synonym: "regulation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-05-12T08:01:20Z + +[Term] +id: GO:1905196 +name: obsolete positive regulation of ATPase activity, uncoupled +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled." [GO_REF:0000059, GOC:TermGenie, PMID:26545917] +comment: The reason for obsoletion is that the there is no convincing example of a protein with this function. +synonym: "activation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +synonym: "activation of ATPase activity, uncoupled" NARROW [GOC:TermGenie] +synonym: "positive regulation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +synonym: "up regulation of ATPase activity, uncoupled" EXACT [GOC:TermGenie] +synonym: "up-regulation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +synonym: "up-regulation of ATPase activity, uncoupled" EXACT [GOC:TermGenie] +synonym: "upregulation of adenylpyrophosphatase activity" RELATED [GOC:TermGenie] +synonym: "upregulation of ATPase activity, uncoupled" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-05-12T08:01:28Z + +[Term] +id: GO:1905197 +name: endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling +namespace: biological_process +def: "Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid." [GO_REF:0000060, GOC:TermGenie, PMID:23040807] +synonym: "endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid" EXACT [GOC:TermGenie] +is_a: GO:1905129 ! endocannabinoid signaling pathway involved in trans-synaptic signaling +intersection_of: GO:0071926 ! endocannabinoid signaling pathway +intersection_of: part_of GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid +relationship: part_of GO:0098921 ! retrograde trans-synaptic signaling by endocannabinoid +created_by: dos +creation_date: 2016-05-12T14:29:38Z + +[Term] +id: GO:1905198 +name: manchette assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a manchette." [GO_REF:0000079, GOC:krc, GOC:TermGenie, PMID:22319670, PMID:24440897, PMID:26792866] +synonym: "manchette formation" EXACT [GOC:TermGenie] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0007286 ! spermatid development +created_by: krc +creation_date: 2016-05-12T15:19:08Z + +[Term] +id: GO:1905199 +name: manchette disassembly +namespace: biological_process +def: "The disaggregation of a manchette into its constituent components." [GO_REF:0000079, GOC:krc, GOC:TermGenie, PMID:22319670, PMID:24440897, PMID:26792866] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +relationship: part_of GO:0007286 ! spermatid development +created_by: krc +creation_date: 2016-05-12T15:19:16Z + +[Term] +id: GO:1905200 +name: gibberellic acid transmembrane transport +namespace: biological_process +def: "The directed movement of gibberellic acid across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:27139299] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0046865 ! terpenoid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +created_by: lr +creation_date: 2016-05-12T18:20:04Z + +[Term] +id: GO:1905201 +name: gibberellin transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of gibberellin from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, PMID:27139299] +is_a: GO:0005319 ! lipid transporter activity +is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity +created_by: lr +creation_date: 2016-05-12T18:20:13Z + +[Term] +id: GO:1905202 +name: methylcrotonoyl-CoA carboxylase complex +namespace: cellular_component +def: "A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity." [GO_REF:0000088, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22158123] +is_a: GO:1902494 ! catalytic complex +created_by: bf +creation_date: 2016-05-16T11:03:20Z + +[Term] +id: GO:1905203 +name: regulation of connective tissue replacement +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of connective tissue replacement." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25590961] +is_a: GO:0034103 ! regulation of tissue remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097709 ! connective tissue replacement +relationship: regulates GO:0097709 ! connective tissue replacement +created_by: bc +creation_date: 2016-05-17T09:54:18Z + +[Term] +id: GO:1905204 +name: negative regulation of connective tissue replacement +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25590961] +synonym: "down regulation of connective tissue replacement" EXACT [GOC:TermGenie] +synonym: "down-regulation of connective tissue replacement" EXACT [GOC:TermGenie] +synonym: "downregulation of connective tissue replacement" EXACT [GOC:TermGenie] +synonym: "inhibition of connective tissue replacement" NARROW [GOC:TermGenie] +is_a: GO:0034104 ! negative regulation of tissue remodeling +is_a: GO:1905203 ! regulation of connective tissue replacement +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097709 ! connective tissue replacement +relationship: negatively_regulates GO:0097709 ! connective tissue replacement +created_by: bc +creation_date: 2016-05-17T09:54:27Z + +[Term] +id: GO:1905205 +name: positive regulation of connective tissue replacement +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of connective tissue replacement." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:25590961] +synonym: "activation of connective tissue replacement" NARROW [GOC:TermGenie] +synonym: "up regulation of connective tissue replacement" EXACT [GOC:TermGenie] +synonym: "up-regulation of connective tissue replacement" EXACT [GOC:TermGenie] +synonym: "upregulation of connective tissue replacement" EXACT [GOC:TermGenie] +is_a: GO:0034105 ! positive regulation of tissue remodeling +is_a: GO:1905203 ! regulation of connective tissue replacement +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097709 ! connective tissue replacement +relationship: positively_regulates GO:0097709 ! connective tissue replacement +created_by: bc +creation_date: 2016-05-17T09:54:35Z + +[Term] +id: GO:1905206 +name: positive regulation of hydrogen peroxide-induced cell death +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:20550618] +synonym: "activation of cell death in response to H2O2" NARROW [GOC:TermGenie] +synonym: "activation of cell death in response to hydrogen peroxide" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "positive regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "positive regulation of cell death in response to hydrogen peroxide" EXACT [] +synonym: "positive regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "up regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "up regulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "up-regulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +synonym: "upregulation of cell death in response to H2O2" EXACT [GOC:TermGenie] +synonym: "upregulation of cell death in response to hydrogen peroxide" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen peroxide-mediated cell death" RELATED [GOC:TermGenie] +is_a: GO:1901033 ! positive regulation of response to reactive oxygen species +is_a: GO:1903205 ! regulation of hydrogen peroxide-induced cell death +is_a: GO:1903209 ! positive regulation of oxidative stress-induced cell death +is_a: GO:2001040 ! positive regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036474 ! cell death in response to hydrogen peroxide +relationship: positively_regulates GO:0036474 ! cell death in response to hydrogen peroxide +created_by: bc +creation_date: 2016-05-20T13:13:39Z + +[Term] +id: GO:1905207 +name: regulation of cardiocyte differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035051 ! cardiocyte differentiation +relationship: regulates GO:0035051 ! cardiocyte differentiation +created_by: bc +creation_date: 2016-06-02T07:20:01Z + +[Term] +id: GO:1905208 +name: negative regulation of cardiocyte differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of cardiocyte differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of heart cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035051 ! cardiocyte differentiation +relationship: negatively_regulates GO:0035051 ! cardiocyte differentiation +created_by: bc +creation_date: 2016-06-02T07:20:09Z + +[Term] +id: GO:1905209 +name: positive regulation of cardiocyte differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "activation of cardiac cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of cardiocyte differentiation" NARROW [GOC:TermGenie] +synonym: "activation of heart cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035051 ! cardiocyte differentiation +relationship: positively_regulates GO:0035051 ! cardiocyte differentiation +created_by: bc +creation_date: 2016-06-02T07:20:16Z + +[Term] +id: GO:1905210 +name: regulation of fibroblast chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibroblast chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:8760137] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990956 ! fibroblast chemotaxis +relationship: regulates GO:1990956 ! fibroblast chemotaxis +created_by: sl +creation_date: 2016-06-02T20:08:42Z + +[Term] +id: GO:1905211 +name: negative regulation of fibroblast chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:8760137] +synonym: "down regulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +synonym: "down-regulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +synonym: "downregulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +synonym: "inhibition of fibroblast chemotaxis" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:1905210 ! regulation of fibroblast chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990956 ! fibroblast chemotaxis +relationship: negatively_regulates GO:1990956 ! fibroblast chemotaxis +created_by: sl +creation_date: 2016-06-02T20:08:51Z + +[Term] +id: GO:1905212 +name: positive regulation of fibroblast chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis." [GO_REF:0000058, GOC:TermGenie, PMID:8760137] +synonym: "activation of fibroblast chemotaxis" NARROW [GOC:TermGenie] +synonym: "up regulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +synonym: "up-regulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +synonym: "upregulation of fibroblast chemotaxis" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1905210 ! regulation of fibroblast chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990956 ! fibroblast chemotaxis +relationship: positively_regulates GO:1990956 ! fibroblast chemotaxis +created_by: sl +creation_date: 2016-06-02T20:08:59Z + +[Term] +id: GO:1905213 +name: negative regulation of mitotic chromosome condensation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725] +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:1902340 ! negative regulation of chromosome condensation +is_a: GO:1903379 ! regulation of mitotic chromosome condensation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007076 ! mitotic chromosome condensation +relationship: negatively_regulates GO:0007076 ! mitotic chromosome condensation +created_by: vw +creation_date: 2016-06-03T08:41:08Z + +[Term] +id: GO:1905214 +name: regulation of RNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA binding." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003723 ! RNA binding +relationship: regulates GO:0003723 ! RNA binding +created_by: bf +creation_date: 2016-06-06T10:20:56Z + +[Term] +id: GO:1905215 +name: negative regulation of RNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of RNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA binding" NARROW [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1905214 ! regulation of RNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003723 ! RNA binding +relationship: negatively_regulates GO:0003723 ! RNA binding +created_by: bf +creation_date: 2016-06-06T10:21:04Z + +[Term] +id: GO:1905216 +name: positive regulation of RNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA binding." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:25116364] +synonym: "activation of RNA binding" NARROW [GOC:TermGenie] +synonym: "up regulation of RNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1905214 ! regulation of RNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003723 ! RNA binding +relationship: positively_regulates GO:0003723 ! RNA binding +created_by: bf +creation_date: 2016-06-06T10:21:12Z + +[Term] +id: GO:1905217 +name: response to astaxanthin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22309505] +synonym: "response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione" EXACT [] +is_a: GO:0033993 ! response to lipid +is_a: GO:0061476 ! response to anticoagulant +created_by: sl +creation_date: 2016-06-06T21:30:00Z + +[Term] +id: GO:1905218 +name: cellular response to astaxanthin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22309505] +synonym: "cellular response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1905217 ! response to astaxanthin +created_by: sl +creation_date: 2016-06-06T21:30:09Z + +[Term] +id: GO:1905219 +name: regulation of platelet formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of platelet formation." [GO_REF:0000058, GOC:TermGenie, PMID:10606160] +synonym: "regulation of platelet extrusion" EXACT [GOC:TermGenie] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:0045637 ! regulation of myeloid cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030220 ! platelet formation +relationship: regulates GO:0030220 ! platelet formation +created_by: sl +creation_date: 2016-06-06T22:15:46Z + +[Term] +id: GO:1905220 +name: negative regulation of platelet formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation." [GO_REF:0000058, GOC:TermGenie, PMID:10606160] +synonym: "down regulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "down regulation of platelet formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of platelet formation" EXACT [GOC:TermGenie] +synonym: "downregulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "downregulation of platelet formation" EXACT [GOC:TermGenie] +synonym: "inhibition of platelet extrusion" NARROW [GOC:TermGenie] +synonym: "inhibition of platelet formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of platelet extrusion" EXACT [GOC:TermGenie] +is_a: GO:0010771 ! negative regulation of cell morphogenesis involved in differentiation +is_a: GO:0045638 ! negative regulation of myeloid cell differentiation +is_a: GO:1905219 ! regulation of platelet formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030220 ! platelet formation +relationship: negatively_regulates GO:0030220 ! platelet formation +created_by: sl +creation_date: 2016-06-06T22:15:54Z + +[Term] +id: GO:1905221 +name: positive regulation of platelet formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of platelet formation." [GO_REF:0000058, GOC:TermGenie, PMID:10606160] +synonym: "activation of platelet extrusion" NARROW [GOC:TermGenie] +synonym: "activation of platelet formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "up regulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "up regulation of platelet formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of platelet formation" EXACT [GOC:TermGenie] +synonym: "upregulation of platelet extrusion" EXACT [GOC:TermGenie] +synonym: "upregulation of platelet formation" EXACT [GOC:TermGenie] +is_a: GO:0010770 ! positive regulation of cell morphogenesis involved in differentiation +is_a: GO:0045639 ! positive regulation of myeloid cell differentiation +is_a: GO:1905219 ! regulation of platelet formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030220 ! platelet formation +relationship: positively_regulates GO:0030220 ! platelet formation +created_by: sl +creation_date: 2016-06-06T22:16:02Z + +[Term] +id: GO:1905222 +name: atrioventricular canal morphogenesis +namespace: biological_process +def: "The developmental process by which an atrioventricular canal is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19703439] +synonym: "atrial canal morphogenesis" EXACT [GOC:TermGenie] +synonym: "atrio-ventricular canal morphogenesis" EXACT [GOC:TermGenie] +synonym: "AV canal morphogenesis" EXACT [GOC:TermGenie] +synonym: "AVC morphogenesis" EXACT [GOC:TermGenie] +synonym: "canalis atrioventricularis morphogenesis" RELATED [GOC:TermGenie] +synonym: "ependymal canal morphogenesis" RELATED [GOC:TermGenie] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: rl +creation_date: 2016-06-07T09:09:51Z + +[Term] +id: GO:1905223 +name: epicardium morphogenesis +namespace: biological_process +def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] +synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie] +synonym: "pericardium visceral mesothelium morphogenesis" RELATED [GOC:TermGenie] +synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie] +synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: rl +creation_date: 2016-06-07T10:02:32Z + +[Term] +id: GO:1905224 +name: clathrin-coated pit assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] +synonym: "clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "coated pit assembly" EXACT [GOC:TermGenie] +synonym: "coated pit formation" EXACT [GOC:TermGenie] +is_a: GO:0071709 ! membrane assembly +relationship: has_part GO:0010324 ! membrane invagination +relationship: has_part GO:0048268 ! clathrin coat assembly +created_by: bf +creation_date: 2016-06-07T11:33:28Z + +[Term] +id: GO:1905225 +name: response to thyrotropin-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary." [GO_REF:0000071, GOC:sl, GOC:TermGenie, PMID:21382270] +synonym: "response to protirelin" EXACT [] +synonym: "response to TRH" RELATED [] +is_a: GO:0043434 ! response to peptide hormone +created_by: pr +creation_date: 2016-06-07T12:11:28Z + +[Term] +id: GO:1905226 +name: regulation of adhesion of symbiont to host epithelial cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell." [GO_REF:0000058, GOC:TermGenie, PMID:15659068] +is_a: GO:0043903 ! regulation of interspecies interactions between organisms +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +relationship: regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +created_by: pga +creation_date: 2016-06-07T13:15:08Z + +[Term] +id: GO:1905227 +name: negative regulation of adhesion of symbiont to host epithelial cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell." [GO_REF:0000058, GOC:TermGenie, PMID:15659068] +synonym: "down regulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +synonym: "downregulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +synonym: "inhibition of adhesion of symbiont to host epithelial cell" NARROW [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1905226 ! regulation of adhesion of symbiont to host epithelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +relationship: negatively_regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +created_by: pga +creation_date: 2016-06-07T13:15:16Z + +[Term] +id: GO:1905228 +name: positive regulation of adhesion of symbiont to host epithelial cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell." [GO_REF:0000058, GOC:TermGenie, PMID:15659068] +synonym: "activation of adhesion of symbiont to host epithelial cell" NARROW [GOC:TermGenie] +synonym: "up regulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +synonym: "upregulation of adhesion of symbiont to host epithelial cell" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1905226 ! regulation of adhesion of symbiont to host epithelial cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +relationship: positively_regulates GO:0044651 ! adhesion of symbiont to host epithelial cell +created_by: pga +creation_date: 2016-06-07T13:15:24Z + +[Term] +id: GO:1905229 +name: cellular response to thyrotropin-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary." [GO_REF:0000071, GOC:TermGenie, PMID:21382270] +synonym: "cellular response to protirelin" EXACT [] +synonym: "cellular response to TRH" RELATED [] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1905225 ! response to thyrotropin-releasing hormone +created_by: sl +creation_date: 2016-06-07T16:14:10Z + +[Term] +id: GO:1905230 +name: response to borneol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26593909] +is_a: GO:0033993 ! response to lipid +created_by: sl +creation_date: 2016-06-07T17:18:36Z + +[Term] +id: GO:1905231 +name: cellular response to borneol +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26593909] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1905230 ! response to borneol +created_by: sl +creation_date: 2016-06-07T17:18:44Z + +[Term] +id: GO:1905232 +name: cellular response to L-glutamate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25962137] +synonym: "cellular response to L-glutamate(1-)" RELATED [] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1902065 ! response to L-glutamate +created_by: sl +creation_date: 2016-06-07T17:30:08Z + +[Term] +id: GO:1905233 +name: response to codeine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +is_a: GO:0009410 ! response to xenobiotic stimulus +is_a: GO:0014072 ! response to isoquinoline alkaloid +is_a: GO:0042493 ! response to drug +created_by: sl +creation_date: 2016-06-07T21:26:45Z + +[Term] +id: GO:1905234 +name: cellular response to codeine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071317 ! cellular response to isoquinoline alkaloid +is_a: GO:0071466 ! cellular response to xenobiotic stimulus +is_a: GO:1905233 ! response to codeine +created_by: sl +creation_date: 2016-06-07T21:26:53Z + +[Term] +id: GO:1905235 +name: response to quercetin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +is_a: GO:0009725 ! response to hormone +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1905395 ! response to flavonoid +created_by: sl +creation_date: 2016-06-07T21:29:40Z + +[Term] +id: GO:1905236 +name: cellular response to quercetin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +is_a: GO:0032870 ! cellular response to hormone stimulus +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:1905235 ! response to quercetin +is_a: GO:1905396 ! cellular response to flavonoid +created_by: sl +creation_date: 2016-06-07T21:29:48Z + +[Term] +id: GO:1905237 +name: response to cyclosporin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +synonym: "response to cyclophilin" EXACT [] +is_a: GO:0042493 ! response to drug +is_a: GO:0046677 ! response to antibiotic +is_a: GO:1901652 ! response to peptide +created_by: sl +creation_date: 2016-06-07T21:32:06Z + +[Term] +id: GO:1905238 +name: cellular response to cyclosporin A +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:24914722] +synonym: "cellular response to cyclophilin" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:1901653 ! cellular response to peptide +is_a: GO:1905237 ! response to cyclosporin A +created_by: sl +creation_date: 2016-06-07T21:32:14Z + +[Term] +id: GO:1905239 +name: regulation of canonical Wnt signaling pathway involved in osteoblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19342382] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045667 ! regulation of osteoblast differentiation +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +relationship: regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +created_by: rph +creation_date: 2016-06-08T10:26:33Z + +[Term] +id: GO:1905240 +name: negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19342382] +synonym: "down regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045668 ! negative regulation of osteoblast differentiation +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:1905239 ! regulation of canonical Wnt signaling pathway involved in osteoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +relationship: negatively_regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +created_by: rph +creation_date: 2016-06-08T10:26:41Z + +[Term] +id: GO:1905241 +name: positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19342382] +synonym: "activation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "activation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045669 ! positive regulation of osteoblast differentiation +is_a: GO:0090263 ! positive regulation of canonical Wnt signaling pathway +is_a: GO:1905239 ! regulation of canonical Wnt signaling pathway involved in osteoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +relationship: positively_regulates GO:0044339 ! canonical Wnt signaling pathway involved in osteoblast differentiation +created_by: rph +creation_date: 2016-06-08T10:26:49Z + +[Term] +id: GO:1905242 +name: response to 3,3',5-triiodo-L-thyronine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21382270] +synonym: "response to Liothyronin" EXACT [] +synonym: "response to Liothyronine" EXACT [] +synonym: "response to Liothyroninum" EXACT [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0043200 ! response to amino acid +is_a: GO:0097066 ! response to thyroid hormone +created_by: sl +creation_date: 2016-06-08T17:42:04Z + +[Term] +id: GO:1905243 +name: cellular response to 3,3',5-triiodo-L-thyronine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21382270] +synonym: "cellular response to Liothyronin" EXACT [] +synonym: "cellular response to Liothyronine" EXACT [] +synonym: "cellular response to Liothyroninum" EXACT [] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0097067 ! cellular response to thyroid hormone stimulus +is_a: GO:1905242 ! response to 3,3',5-triiodo-L-thyronine +created_by: sl +creation_date: 2016-06-08T17:42:12Z + +[Term] +id: GO:1905244 +name: regulation of modification of synaptic structure +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of modification of synaptic structure." [GO_REF:0000058, GOC:TermGenie, PMID:25164660] +subset: goslim_synapse +synonym: "regulation of synapse remodelling" EXACT [GOC:TermGenie] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099563 ! modification of synaptic structure +relationship: regulates GO:0099563 ! modification of synaptic structure +created_by: dos +creation_date: 2016-06-09T09:43:40Z + +[Term] +id: GO:1905245 +name: regulation of aspartic-type peptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity." [GO_REF:0000059, GOC:jl, GOC:TermGenie, PMID:21745575] +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070001 ! aspartic-type peptidase activity +relationship: regulates GO:0070001 ! aspartic-type peptidase activity +created_by: jl +creation_date: 2016-06-09T11:55:39Z + +[Term] +id: GO:1905246 +name: negative regulation of aspartic-type peptidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity." [GO_REF:0000059, GOC:jl, GOC:TermGenie, PMID:21745575] +synonym: "down regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of aspartic-type peptidase activity" NARROW [GOC:TermGenie] +synonym: "pepsin inhibitor" RELATED [] +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:1905245 ! regulation of aspartic-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070001 ! aspartic-type peptidase activity +relationship: negatively_regulates GO:0070001 ! aspartic-type peptidase activity +created_by: jl +creation_date: 2016-06-09T11:55:47Z + +[Term] +id: GO:1905247 +name: positive regulation of aspartic-type peptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity." [GO_REF:0000059, GOC:jl, GOC:TermGenie, PMID:21745575] +synonym: "activation of aspartic-type peptidase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] +is_a: GO:0010952 ! positive regulation of peptidase activity +is_a: GO:1905245 ! regulation of aspartic-type peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070001 ! aspartic-type peptidase activity +relationship: positively_regulates GO:0070001 ! aspartic-type peptidase activity +created_by: jl +creation_date: 2016-06-09T11:55:55Z + +[Term] +id: GO:1905248 +name: obsolete regulation of memory +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of memory." [GO_REF:0000058, GOC:TermGenie, PMID:25905804] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "modulation of memory" NARROW [] +is_obsolete: true +created_by: ha +creation_date: 2016-06-09T13:54:38Z + +[Term] +id: GO:1905249 +name: obsolete negative regulation of memory +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of memory." [GO_REF:0000058, GOC:TermGenie, PMID:25905804] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "inhibition of memory" NARROW [GOC:TermGenie] +synonym: "suppression of memory" EXACT [] +is_obsolete: true +created_by: ha +creation_date: 2016-06-09T13:54:45Z + +[Term] +id: GO:1905250 +name: obsolete positive regulation of memory +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of memory." [GO_REF:0000058, GOC:TermGenie, PMID:25905804] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "enhancement of memory" NARROW [] +is_obsolete: true +created_by: ha +creation_date: 2016-06-09T13:54:53Z + +[Term] +id: GO:1905251 +name: epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any epidermal growth factor receptor signaling pathway that is involved in heart process." [GO_REF:0000060, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +is_a: GO:0007173 ! epidermal growth factor receptor signaling pathway +intersection_of: GO:0007173 ! epidermal growth factor receptor signaling pathway +intersection_of: part_of GO:0003015 ! heart process +relationship: part_of GO:0003015 ! heart process +created_by: bc +creation_date: 2016-06-10T09:20:54Z + +[Term] +id: GO:1905252 +name: obsolete regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any regulation of epidermal growth factor receptor signaling pathway that is involved in heart process." [GO_REF:0000060, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: bc +creation_date: 2016-06-10T09:21:02Z + +[Term] +id: GO:1905253 +name: obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any negative regulation of epidermal growth factor receptor signaling pathway that is involved in heart process." [GO_REF:0000060, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: bc +creation_date: 2016-06-10T09:21:10Z + +[Term] +id: GO:1905254 +name: obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process." [GO_REF:0000060, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of epidermal growth factor receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "stimulation of epidermal growth factor receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bc +creation_date: 2016-06-10T09:21:18Z + +[Term] +id: GO:1905255 +name: regulation of RNA binding transcription factor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:25116364] +synonym: "regulation of transcription factor activity" BROAD [GOC:TermGenie] +is_a: GO:0065009 ! regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001070 ! RNA-binding transcription regulator activity +relationship: regulates GO:0001070 ! RNA-binding transcription regulator activity +created_by: bf +creation_date: 2016-06-13T11:29:11Z + +[Term] +id: GO:1905256 +name: negative regulation of RNA binding transcription factor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +synonym: "inhibition of RNA binding transcription factor activity" NARROW [GOC:TermGenie] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:1905255 ! regulation of RNA binding transcription factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001070 ! RNA-binding transcription regulator activity +relationship: negatively_regulates GO:0001070 ! RNA-binding transcription regulator activity +created_by: bf +creation_date: 2016-06-13T11:29:20Z + +[Term] +id: GO:1905257 +name: positive regulation of RNA binding transcription factor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:25116364] +synonym: "activation of RNA binding transcription factor activity" NARROW [GOC:TermGenie] +synonym: "up regulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA binding transcription factor activity" EXACT [GOC:TermGenie] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:1905255 ! regulation of RNA binding transcription factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001070 ! RNA-binding transcription regulator activity +relationship: positively_regulates GO:0001070 ! RNA-binding transcription regulator activity +created_by: bf +creation_date: 2016-06-13T11:29:27Z + +[Term] +id: GO:1905258 +name: regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:14752510] +synonym: "regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:bf] +synonym: "regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:0080135 ! regulation of cellular response to stress +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +relationship: regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +created_by: bf +creation_date: 2016-06-13T17:04:59Z + +[Term] +id: GO:1905259 +name: negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:14752510] +synonym: "down regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "down regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "down regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "down-regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "down-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "downregulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "downregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of intrinsic apoptotic signaling pathway in response to nitrosative stress" NARROW [GOC:TermGenie] +synonym: "inhibition of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "inhibition of nitrosative stress-induced intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:bf] +synonym: "negative regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1905258 ! regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:2001243 ! negative regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +relationship: negatively_regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +created_by: bf +creation_date: 2016-06-13T17:05:07Z + +[Term] +id: GO:1905260 +name: positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of intrinsic apoptotic signaling pathway in response to nitrosative stress" NARROW [GOC:TermGenie] +synonym: "activation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "activation of nitrosative stress-induced intrinsic apoptotic signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:bf] +synonym: "positive regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "up regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "up regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "up-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress" EXACT [GOC:TermGenie] +synonym: "upregulation of nitrosative stress-induced apoptosis" RELATED [GOC:TermGenie] +synonym: "upregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1905258 ! regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway +is_a: GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +relationship: positively_regulates GO:1990442 ! intrinsic apoptotic signaling pathway in response to nitrosative stress +created_by: bf +creation_date: 2016-06-13T17:05:15Z + +[Term] +id: GO:1905261 +name: regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination." [GO_REF:0000058, GOC:TermGenie, PMID:26653857] +is_a: GO:0010520 ! regulation of reciprocal meiotic recombination +is_a: GO:1903341 ! regulation of meiotic DNA double-strand break formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +relationship: regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +created_by: se +creation_date: 2016-06-13T20:45:02Z + +[Term] +id: GO:1905262 +name: negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination." [GO_REF:0000058, GOC:TermGenie, PMID:26653857] +synonym: "down regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +synonym: "down-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +synonym: "downregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +synonym: "inhibition of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" NARROW [GOC:TermGenie] +is_a: GO:0045128 ! negative regulation of reciprocal meiotic recombination +is_a: GO:1903342 ! negative regulation of meiotic DNA double-strand break formation +is_a: GO:1905261 ! regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +relationship: negatively_regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +created_by: se +creation_date: 2016-06-13T20:45:10Z + +[Term] +id: GO:1905263 +name: positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination." [GO_REF:0000058, GOC:TermGenie, PMID:26653857] +synonym: "activation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" NARROW [GOC:TermGenie] +synonym: "up regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +synonym: "upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination" EXACT [GOC:TermGenie] +is_a: GO:0010845 ! positive regulation of reciprocal meiotic recombination +is_a: GO:1903343 ! positive regulation of meiotic DNA double-strand break formation +is_a: GO:1905261 ! regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +relationship: positively_regulates GO:0010780 ! meiotic DNA double-strand break formation involved in reciprocal meiotic recombination +created_by: se +creation_date: 2016-06-13T20:45:18Z + +[Term] +id: GO:1905264 +name: blasticidin S metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving blasticidin S." [GO_REF:0000068, GOC:pr, GOC:TermGenie, PMID:23874663, Wikipedia:Blasticidin_S] +synonym: "blasticidin S metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006213 ! pyrimidine nucleoside metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +created_by: pr +creation_date: 2016-06-14T12:47:05Z + +[Term] +id: GO:1905265 +name: blasticidin S catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of blasticidin S." [GO_REF:0000068, GOC:pr, GOC:TermGenie, PMID:23874663, Wikipedia:Blasticidin_S] +synonym: "blasticidin S breakdown" EXACT [GOC:TermGenie] +synonym: "blasticidin S catabolism" EXACT [GOC:TermGenie] +synonym: "blasticidin S degradation" EXACT [GOC:TermGenie] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0046135 ! pyrimidine nucleoside catabolic process +is_a: GO:1905264 ! blasticidin S metabolic process +created_by: pr +creation_date: 2016-06-14T12:47:13Z + +[Term] +id: GO:1905266 +name: blasticidin S biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of blasticidin S." [GO_REF:0000068, GOC:pr, GOC:TermGenie, PMID:23874663, Wikipedia:Blasticidin_S] +synonym: "blasticidin S anabolism" EXACT [GOC:TermGenie] +synonym: "blasticidin S biosynthesis" EXACT [GOC:TermGenie] +synonym: "blasticidin S formation" EXACT [GOC:TermGenie] +synonym: "blasticidin S synthesis" EXACT [GOC:TermGenie] +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0046134 ! pyrimidine nucleoside biosynthetic process +is_a: GO:1905264 ! blasticidin S metabolic process +created_by: pr +creation_date: 2016-06-14T12:47:22Z + +[Term] +id: GO:1905267 +name: endonucleolytic cleavage involved in tRNA processing +namespace: biological_process +def: "Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing." [GO_REF:0000060, GOC:TermGenie, PMID:25401760] +synonym: "RNA phosphodiester bond hydrolysis, endonucleolytic involved in tRNA maturation" EXACT [GOC:TermGenie] +is_a: GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic +intersection_of: GO:0090502 ! RNA phosphodiester bond hydrolysis, endonucleolytic +intersection_of: part_of GO:0008033 ! tRNA processing +relationship: part_of GO:0008033 ! tRNA processing +created_by: al +creation_date: 2016-06-14T14:54:54Z + +[Term] +id: GO:1905268 +name: negative regulation of chromatin organization +namespace: biological_process +alt_id: GO:1903309 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] +synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "inhibition of chromatin organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of chromatin organization" NARROW [GOC:TermGenie] +synonym: "inhibition of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] +synonym: "negative regulation of chromatin modification" RELATED [] +synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +is_a: GO:1902275 ! regulation of chromatin organization +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006325 ! chromatin organization +relationship: negatively_regulates GO:0006325 ! chromatin organization +created_by: pr +creation_date: 2016-06-15T20:14:47Z + +[Term] +id: GO:1905269 +name: positive regulation of chromatin organization +namespace: biological_process +alt_id: GO:1903310 +def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] +synonym: "activation of chromatin organisation" NARROW [GOC:TermGenie] +synonym: "activation of chromatin organization" NARROW [GOC:TermGenie] +synonym: "activation of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] +synonym: "positive regulation of chromatin modification" RELATED [] +synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie] +synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] +is_a: GO:1902275 ! regulation of chromatin organization +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006325 ! chromatin organization +relationship: positively_regulates GO:0006325 ! chromatin organization +created_by: pr +creation_date: 2016-06-15T20:14:56Z + +[Term] +id: GO:1905270 +name: Meynert cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell." [GO_REF:0000086, GOC:TermGenie, PMID:4142639] +is_a: GO:0021859 ! pyramidal neuron differentiation +is_a: GO:0021879 ! forebrain neuron differentiation +is_a: GO:0021895 ! cerebral cortex neuron differentiation +created_by: cjm +creation_date: 2016-06-15T23:44:17Z + +[Term] +id: GO:1905271 +name: regulation of proton-transporting ATP synthase activity, rotational mechanism +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:21106936] +synonym: "regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0051338 ! regulation of transferase activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +relationship: regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +created_by: als +creation_date: 2016-06-16T12:09:49Z + +[Term] +id: GO:1905272 +name: negative regulation of proton-transporting ATP synthase activity, rotational mechanism +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:21106936] +synonym: "down regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "down regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "down-regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "down-regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "downregulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "downregulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "inhibition of H+-transporting ATP synthase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen ion translocating F-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen ion transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] +synonym: "inhibition of hydrogen ion transporting two-sector ATPase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of proton-transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] +synonym: "negative regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "negative regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1905271 ! regulation of proton-transporting ATP synthase activity, rotational mechanism +is_a: GO:2001258 ! negative regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +relationship: negatively_regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +created_by: als +creation_date: 2016-06-16T12:09:57Z + +[Term] +id: GO:1905273 +name: positive regulation of proton-transporting ATP synthase activity, rotational mechanism +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:21106936] +synonym: "activation of H+-transporting ATP synthase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen ion translocating F-type ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen ion transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] +synonym: "activation of hydrogen ion transporting two-sector ATPase activity" NARROW [GOC:TermGenie] +synonym: "activation of proton-transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] +synonym: "positive regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "positive regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "up regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "up-regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "up-regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "upregulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +synonym: "upregulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1905271 ! regulation of proton-transporting ATP synthase activity, rotational mechanism +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +relationship: positively_regulates GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism +created_by: als +creation_date: 2016-06-16T12:10:05Z + +[Term] +id: GO:1905274 +name: regulation of modification of postsynaptic actin cytoskeleton +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton." [GO_REF:0000058, GOC:TermGenie, PMID:21068295] +subset: goslim_synapse +synonym: "regulation of postsynaptic actin cytoskeleton remodelling" EXACT [GOC:TermGenie] +is_a: GO:0099159 ! regulation of modification of postsynaptic structure +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098885 ! modification of postsynaptic actin cytoskeleton +relationship: regulates GO:0098885 ! modification of postsynaptic actin cytoskeleton +created_by: dos +creation_date: 2016-06-16T22:34:25Z + +[Term] +id: GO:1905275 +name: Rohon-Beard neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron." [GO_REF:0000086, GOC:TermGenie, ZFIN:ZDB-PUB-120807-45] +is_a: GO:0030182 ! neuron differentiation +created_by: cjm +creation_date: 2016-06-16T23:17:04Z + +[Term] +id: GO:1905276 +name: regulation of epithelial tube formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072175 ! epithelial tube formation +relationship: regulates GO:0072175 ! epithelial tube formation +created_by: bhm +creation_date: 2016-06-20T09:35:41Z + +[Term] +id: GO:1905277 +name: negative regulation of epithelial tube formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelial tube formation" NARROW [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905276 ! regulation of epithelial tube formation +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072175 ! epithelial tube formation +relationship: negatively_regulates GO:0072175 ! epithelial tube formation +created_by: bhm +creation_date: 2016-06-20T09:35:49Z + +[Term] +id: GO:1905278 +name: positive regulation of epithelial tube formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +synonym: "activation of epithelial tube formation" NARROW [GOC:TermGenie] +synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905276 ! regulation of epithelial tube formation +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072175 ! epithelial tube formation +relationship: positively_regulates GO:0072175 ! epithelial tube formation +created_by: bhm +creation_date: 2016-06-20T09:35:57Z + +[Term] +id: GO:1905279 +name: regulation of retrograde transport, endosome to Golgi +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23395371] +synonym: "regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042147 ! retrograde transport, endosome to Golgi +relationship: regulates GO:0042147 ! retrograde transport, endosome to Golgi +created_by: bf +creation_date: 2016-06-20T12:25:29Z + +[Term] +id: GO:1905280 +name: negative regulation of retrograde transport, endosome to Golgi +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "down regulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +synonym: "inhibition of retrograde (endosome to Golgi) transport" NARROW [GOC:TermGenie] +synonym: "inhibition of retrograde transport, endosome to Golgi" NARROW [GOC:TermGenie] +synonym: "negative regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +is_a: GO:1903650 ! negative regulation of cytoplasmic transport +is_a: GO:1905279 ! regulation of retrograde transport, endosome to Golgi +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042147 ! retrograde transport, endosome to Golgi +relationship: negatively_regulates GO:0042147 ! retrograde transport, endosome to Golgi +created_by: bf +creation_date: 2016-06-20T12:25:37Z + +[Term] +id: GO:1905281 +name: positive regulation of retrograde transport, endosome to Golgi +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of retrograde (endosome to Golgi) transport" NARROW [GOC:TermGenie] +synonym: "activation of retrograde transport, endosome to Golgi" NARROW [GOC:TermGenie] +synonym: "positive regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "up regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "up regulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +synonym: "up-regulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde (endosome to Golgi) transport" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde transport, endosome to Golgi" EXACT [GOC:TermGenie] +is_a: GO:1903651 ! positive regulation of cytoplasmic transport +is_a: GO:1905279 ! regulation of retrograde transport, endosome to Golgi +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042147 ! retrograde transport, endosome to Golgi +relationship: positively_regulates GO:0042147 ! retrograde transport, endosome to Golgi +created_by: bf +creation_date: 2016-06-20T12:25:44Z + +[Term] +id: GO:1905282 +name: regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +is_a: GO:0042058 ! regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0044057 ! regulation of system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +relationship: regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +created_by: bc +creation_date: 2016-06-20T14:40:41Z + +[Term] +id: GO:1905283 +name: negative regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "down regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "inhibition of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of EGF receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of EGF receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of EGFR signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of epidermal growth factor receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of ERBB1 signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +is_a: GO:0042059 ! negative regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905282 ! regulation of epidermal growth factor receptor signaling pathway involved in heart process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +relationship: negatively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +created_by: bc +creation_date: 2016-06-20T14:40:49Z + +[Term] +id: GO:1905284 +name: positive regulation of epidermal growth factor receptor signaling pathway involved in heart process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] +synonym: "activation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of EGF receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of EGF receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of EGFR signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of epidermal growth factor receptor signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of epidermal growth factor receptor signalling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of ERBB1 signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" NARROW [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of EGF receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of EGF receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of EGF receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of EGF receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of EGFR signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of EGFR signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signalling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of epidermal growth factor receptor signalling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of ERBB1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of ERBB1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process" EXACT [GOC:TermGenie] +is_a: GO:0045742 ! positive regulation of epidermal growth factor receptor signaling pathway +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905282 ! regulation of epidermal growth factor receptor signaling pathway involved in heart process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +relationship: positively_regulates GO:1905251 ! epidermal growth factor receptor signaling pathway involved in heart process +created_by: bc +creation_date: 2016-06-20T14:40:57Z + +[Term] +id: GO:1905285 +name: fibrous ring of heart morphogenesis +namespace: biological_process +def: "The developmental process by which a fibrous ring of heart is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16037571] +synonym: "annulus fibrosus cordis morphogenesis" RELATED [GOC:TermGenie] +synonym: "anulus fibrosus cordis morphogenesis" RELATED [GOC:TermGenie] +synonym: "anulus fibrosus of heart morphogenesis" EXACT [GOC:TermGenie] +synonym: "aortic annulus morphogenesis" RELATED [GOC:TermGenie] +synonym: "atrioventricular ring morphogenesis" RELATED [GOC:TermGenie] +synonym: "coronary tendon morphogenesis" RELATED [GOC:TermGenie] +synonym: "Lower's ring morphogenesis" RELATED [GOC:TermGenie] +is_a: GO:0048729 ! tissue morphogenesis +created_by: rl +creation_date: 2016-06-21T09:46:54Z + +[Term] +id: GO:1905286 +name: serine-type peptidase complex +namespace: cellular_component +def: "A protein complex which is capable of serine-type peptidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18640965] +comment: An example of this is F7 in human (P08709) in PMID:18640965 (inferred from direct assay). +synonym: "Factor VII - TF complex" NARROW [] +is_a: GO:1905368 ! peptidase complex +created_by: bhm +creation_date: 2016-06-21T14:20:20Z + +[Term] +id: GO:1905287 +name: positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation +namespace: biological_process +def: "Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation." [GO_REF:0000060, GOC:TermGenie, PMID:26776736] +synonym: "positive regulation of mitotic entry involved in cellular response to nitrogen starvation" EXACT [GOC:TermGenie] +is_a: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle +intersection_of: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle +intersection_of: part_of GO:0006995 ! cellular response to nitrogen starvation +relationship: part_of GO:0006995 ! cellular response to nitrogen starvation +created_by: al +creation_date: 2016-06-21T17:19:33Z + +[Term] +id: GO:1905288 +name: vascular associated smooth muscle cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] +synonym: "vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0034390 ! smooth muscle cell apoptotic process +created_by: rph +creation_date: 2016-06-23T13:24:20Z + +[Term] +id: GO:1905289 +name: regulation of CAMKK-AMPK signaling cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade." [GO_REF:0000058, GOC:TermGenie, PMID:22128786] +synonym: "regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +is_a: GO:0050848 ! regulation of calcium-mediated signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061762 ! CAMKK-AMPK signaling cascade +relationship: regulates GO:0061762 ! CAMKK-AMPK signaling cascade +created_by: sl +creation_date: 2016-06-23T20:36:55Z + +[Term] +id: GO:1905290 +name: negative regulation of CAMKK-AMPK signaling cascade +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade." [GO_REF:0000058, GOC:TermGenie, PMID:22128786] +synonym: "down regulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "down regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "down-regulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "down-regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "downregulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "downregulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "inhibition of CAMKK-AMPK signaling cascade" NARROW [GOC:TermGenie] +synonym: "inhibition of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "negative regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +is_a: GO:0050849 ! negative regulation of calcium-mediated signaling +is_a: GO:1905289 ! regulation of CAMKK-AMPK signaling cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061762 ! CAMKK-AMPK signaling cascade +relationship: negatively_regulates GO:0061762 ! CAMKK-AMPK signaling cascade +created_by: sl +creation_date: 2016-06-23T20:37:03Z + +[Term] +id: GO:1905291 +name: positive regulation of CAMKK-AMPK signaling cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade." [GO_REF:0000058, GOC:TermGenie, PMID:22128786] +synonym: "activation of CAMKK-AMPK signaling cascade" NARROW [GOC:TermGenie] +synonym: "activation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "positive regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "up regulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "up regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "up-regulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "up-regulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +synonym: "upregulation of CAMKK-AMPK signaling cascade" EXACT [GOC:TermGenie] +synonym: "upregulation of stress-activated AMP-activated protein kinase signaling cascade" RELATED [GOC:TermGenie] +is_a: GO:0050850 ! positive regulation of calcium-mediated signaling +is_a: GO:1905289 ! regulation of CAMKK-AMPK signaling cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061762 ! CAMKK-AMPK signaling cascade +relationship: positively_regulates GO:0061762 ! CAMKK-AMPK signaling cascade +created_by: sl +creation_date: 2016-06-23T20:37:10Z + +[Term] +id: GO:1905292 +name: regulation of neural crest cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014033 ! neural crest cell differentiation +relationship: regulates GO:0014033 ! neural crest cell differentiation +created_by: rl +creation_date: 2016-06-28T15:02:01Z + +[Term] +id: GO:1905293 +name: negative regulation of neural crest cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of neural crest cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905292 ! regulation of neural crest cell differentiation +is_a: GO:2000737 ! negative regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014033 ! neural crest cell differentiation +relationship: negatively_regulates GO:0014033 ! neural crest cell differentiation +created_by: rl +creation_date: 2016-06-28T15:02:09Z + +[Term] +id: GO:1905294 +name: positive regulation of neural crest cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +synonym: "activation of neural crest cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905292 ! regulation of neural crest cell differentiation +is_a: GO:2000738 ! positive regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014033 ! neural crest cell differentiation +relationship: positively_regulates GO:0014033 ! neural crest cell differentiation +created_by: rl +creation_date: 2016-06-28T15:02:16Z + +[Term] +id: GO:1905295 +name: regulation of neural crest cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neural crest cell fate specification." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:0090299 ! regulation of neural crest formation +is_a: GO:1905292 ! regulation of neural crest cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014036 ! neural crest cell fate specification +relationship: regulates GO:0014036 ! neural crest cell fate specification +created_by: rl +creation_date: 2016-06-28T15:14:40Z + +[Term] +id: GO:1905296 +name: negative regulation of neural crest cell fate specification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +synonym: "down regulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +synonym: "down-regulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +synonym: "downregulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +synonym: "inhibition of neural crest cell fate specification" NARROW [GOC:TermGenie] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:0090301 ! negative regulation of neural crest formation +is_a: GO:1905293 ! negative regulation of neural crest cell differentiation +is_a: GO:1905295 ! regulation of neural crest cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014036 ! neural crest cell fate specification +relationship: negatively_regulates GO:0014036 ! neural crest cell fate specification +created_by: rl +creation_date: 2016-06-28T15:14:49Z + +[Term] +id: GO:1905297 +name: positive regulation of neural crest cell fate specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] +synonym: "activation of neural crest cell fate specification" NARROW [GOC:TermGenie] +synonym: "up regulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +synonym: "up-regulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +synonym: "upregulation of neural crest cell fate specification" EXACT [GOC:TermGenie] +is_a: GO:0042660 ! positive regulation of cell fate specification +is_a: GO:0090300 ! positive regulation of neural crest formation +is_a: GO:1905294 ! positive regulation of neural crest cell differentiation +is_a: GO:1905295 ! regulation of neural crest cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014036 ! neural crest cell fate specification +relationship: positively_regulates GO:0014036 ! neural crest cell fate specification +created_by: rl +creation_date: 2016-06-28T15:14:57Z + +[Term] +id: GO:1905298 +name: regulation of intestinal epithelial cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060576 ! intestinal epithelial cell development +relationship: regulates GO:0060576 ! intestinal epithelial cell development +created_by: rph +creation_date: 2016-06-30T11:40:47Z + +[Term] +id: GO:1905299 +name: negative regulation of intestinal epithelial cell development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] +synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +synonym: "inhibition of intestinal epithelial cell development" NARROW [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905298 ! regulation of intestinal epithelial cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060576 ! intestinal epithelial cell development +relationship: negatively_regulates GO:0060576 ! intestinal epithelial cell development +created_by: rph +creation_date: 2016-06-30T11:40:55Z + +[Term] +id: GO:1905300 +name: positive regulation of intestinal epithelial cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] +synonym: "activation of intestinal epithelial cell development" NARROW [GOC:TermGenie] +synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905298 ! regulation of intestinal epithelial cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060576 ! intestinal epithelial cell development +relationship: positively_regulates GO:0060576 ! intestinal epithelial cell development +created_by: rph +creation_date: 2016-06-30T11:41:02Z + +[Term] +id: GO:1905301 +name: regulation of macropinocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macropinocytosis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:18691641] +synonym: "regulation of clathrin-independent pinocytosis" BROAD [GOC:TermGenie] +is_a: GO:0048548 ! regulation of pinocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044351 ! macropinocytosis +relationship: regulates GO:0044351 ! macropinocytosis +created_by: pad +creation_date: 2016-07-04T14:16:32Z + +[Term] +id: GO:1905302 +name: negative regulation of macropinocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:18691641] +synonym: "down regulation of macropinocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of macropinocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of macropinocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of macropinocytosis" NARROW [GOC:TermGenie] +is_a: GO:0048550 ! negative regulation of pinocytosis +is_a: GO:1905301 ! regulation of macropinocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044351 ! macropinocytosis +relationship: negatively_regulates GO:0044351 ! macropinocytosis +created_by: pad +creation_date: 2016-07-04T14:16:41Z + +[Term] +id: GO:1905303 +name: positive regulation of macropinocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macropinocytosis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:18691641] +synonym: "activation of macropinocytosis" NARROW [GOC:TermGenie] +synonym: "up regulation of macropinocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of macropinocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of macropinocytosis" EXACT [GOC:TermGenie] +is_a: GO:0048549 ! positive regulation of pinocytosis +is_a: GO:1905301 ! regulation of macropinocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044351 ! macropinocytosis +relationship: positively_regulates GO:0044351 ! macropinocytosis +created_by: pad +creation_date: 2016-07-04T14:16:49Z + +[Term] +id: GO:1905304 +name: regulation of cardiac myofibril assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] +synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0110020 ! regulation of actomyosin structure organization +is_a: GO:1902115 ! regulation of organelle assembly +is_a: GO:1902903 ! regulation of supramolecular fiber organization +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055003 ! cardiac myofibril assembly +relationship: regulates GO:0055003 ! cardiac myofibril assembly +created_by: rl +creation_date: 2016-07-06T10:01:49Z + +[Term] +id: GO:1905305 +name: negative regulation of cardiac myofibril assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] +synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of cardiac myofibril assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of cardiac myofibril development" NARROW [GOC:TermGenie] +synonym: "inhibition of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +is_a: GO:1905304 ! regulation of cardiac myofibril assembly +is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055003 ! cardiac myofibril assembly +relationship: negatively_regulates GO:0055003 ! cardiac myofibril assembly +created_by: rl +creation_date: 2016-07-06T10:01:58Z + +[Term] +id: GO:1905306 +name: positive regulation of cardiac myofibril assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] +synonym: "activation of cardiac myofibril assembly" NARROW [GOC:TermGenie] +synonym: "activation of cardiac myofibril development" NARROW [GOC:TermGenie] +synonym: "activation of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of heart myofibril assembly" RELATED [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +is_a: GO:1905304 ! regulation of cardiac myofibril assembly +is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055003 ! cardiac myofibril assembly +relationship: positively_regulates GO:0055003 ! cardiac myofibril assembly +created_by: rl +creation_date: 2016-07-06T10:02:07Z + +[Term] +id: GO:1905307 +name: response to miconazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26108447] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +created_by: al +creation_date: 2016-07-06T11:55:22Z + +[Term] +id: GO:1905308 +name: cellular response to miconazole +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26108447] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1905307 ! response to miconazole +created_by: al +creation_date: 2016-07-06T11:55:30Z + +[Term] +id: GO:1905309 +name: positive regulation of cohesin loading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cohesin loading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +synonym: "positive regulation of cohesin association with chromatin" EXACT [GOC:TermGenie] +synonym: "positive regulation of cohesin localization to chromatin" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:0045876 ! positive regulation of sister chromatid cohesion +is_a: GO:0071922 ! regulation of cohesin loading +is_a: GO:0120187 ! positive regulation of protein localization to chromatin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071921 ! cohesin loading +relationship: positively_regulates GO:0071921 ! cohesin loading +created_by: vw +creation_date: 2016-07-08T16:12:18Z + +[Term] +id: GO:1905310 +name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0060284 ! regulation of cell development +is_a: GO:1905207 ! regulation of cardiocyte differentiation +is_a: GO:1905292 ! regulation of neural crest cell differentiation +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +relationship: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +created_by: rl +creation_date: 2016-07-11T17:34:26Z + +[Term] +id: GO:1905311 +name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] +synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +is_a: GO:1905293 ! negative regulation of neural crest cell differentiation +is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +relationship: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +created_by: rl +creation_date: 2016-07-11T17:34:35Z + +[Term] +id: GO:1905312 +name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] +synonym: "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:1905209 ! positive regulation of cardiocyte differentiation +is_a: GO:1905294 ! positive regulation of neural crest cell differentiation +is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +relationship: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis +created_by: rl +creation_date: 2016-07-11T17:34:43Z + +[Term] +id: GO:1905313 +name: transforming growth factor beta receptor signaling pathway involved in heart development +namespace: biological_process +def: "Any transforming growth factor beta receptor signaling pathway that is involved in heart development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16140292] +synonym: "TGF-beta receptor signaling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "TGF-beta receptor signaling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "TGF-beta receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "TGF-beta receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "TGFbeta receptor signaling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "TGFbeta receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signaling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signaling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway involved in cardiac development" RELATED [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway involved in dorsal vessel development" NARROW [GOC:TermGenie] +synonym: "transforming growth factor beta receptor signalling pathway involved in heart development" EXACT [GOC:TermGenie] +is_a: GO:0007179 ! transforming growth factor beta receptor signaling pathway +is_a: GO:0061311 ! cell surface receptor signaling pathway involved in heart development +intersection_of: GO:0007179 ! transforming growth factor beta receptor signaling pathway +intersection_of: part_of GO:0007507 ! heart development +created_by: rl +creation_date: 2016-07-11T17:45:38Z + +[Term] +id: GO:1905314 +name: semi-lunar valve development +namespace: biological_process +def: "The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure." [GO_REF:0000094, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19409885] +synonym: "semilunar valve development" EXACT [GOC:TermGenie] +synonym: "semilunar valves development" EXACT [GOC:TermGenie] +is_a: GO:0003170 ! heart valve development +created_by: rl +creation_date: 2016-07-11T17:50:44Z + +[Term] +id: GO:1905315 +name: cell proliferation involved in endocardial cushion morphogenesis +namespace: biological_process +def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948] +is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis +relationship: part_of GO:0003203 ! endocardial cushion morphogenesis +created_by: rl +creation_date: 2016-07-12T13:56:36Z + +[Term] +id: GO:1905316 +name: superior endocardial cushion morphogenesis +namespace: biological_process +def: "The developmental process by which a superior endocardial cushion is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17050629] +synonym: "dorsal endocardial cushion morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0003203 ! endocardial cushion morphogenesis +created_by: rl +creation_date: 2016-07-12T14:08:35Z + +[Term] +id: GO:1905317 +name: inferior endocardial cushion morphogenesis +namespace: biological_process +def: "The developmental process by which an inferior endocardial cushion is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17050629] +synonym: "ventral endocardial cushion morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0003203 ! endocardial cushion morphogenesis +created_by: rl +creation_date: 2016-07-12T14:14:56Z + +[Term] +id: GO:1905318 +name: meiosis I spindle assembly checkpoint +namespace: biological_process +def: "Any spindle assembly checkpoint that is involved in meiosis I." [GO_REF:0000060, GOC:TermGenie, PMID:26483559] +is_a: GO:0033316 ! meiotic spindle assembly checkpoint +is_a: GO:0110029 ! negative regulation of meiosis I +relationship: negatively_regulates GO:0051755 ! meiotic sister chromatid arm separation +created_by: vw +creation_date: 2016-07-13T18:25:06Z + +[Term] +id: GO:1905319 +name: mesenchymal stem cell migration +namespace: biological_process +def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476] +is_a: GO:0016477 ! cell migration +created_by: sl +creation_date: 2016-07-14T17:13:02Z + +[Term] +id: GO:1905320 +name: regulation of mesenchymal stem cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905319 ! mesenchymal stem cell migration +relationship: regulates GO:1905319 ! mesenchymal stem cell migration +created_by: sl +creation_date: 2016-07-15T22:19:14Z + +[Term] +id: GO:1905321 +name: negative regulation of mesenchymal stem cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] +synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +synonym: "inhibition of mesenchymal stem cell migration" NARROW [GOC:TermGenie] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:1905320 ! regulation of mesenchymal stem cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905319 ! mesenchymal stem cell migration +relationship: negatively_regulates GO:1905319 ! mesenchymal stem cell migration +created_by: sl +creation_date: 2016-07-15T22:19:22Z + +[Term] +id: GO:1905322 +name: positive regulation of mesenchymal stem cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] +synonym: "activation of mesenchymal stem cell migration" NARROW [GOC:TermGenie] +synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:1905320 ! regulation of mesenchymal stem cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905319 ! mesenchymal stem cell migration +relationship: positively_regulates GO:1905319 ! mesenchymal stem cell migration +created_by: sl +creation_date: 2016-07-15T22:19:29Z + +[Term] +id: GO:1905323 +name: telomerase holoenzyme complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex." [GO_REF:0000079, GOC:TermGenie, PMID:26305931] +synonym: "telomerase holoenzyme complex formation" EXACT [GOC:TermGenie] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +created_by: mah +creation_date: 2016-07-18T10:38:14Z + +[Term] +id: GO:1905324 +name: telomere-telomerase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex." [GO_REF:0000079, GOC:TermGenie, PMID:26305931] +synonym: "telomere-telomerase complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065004 ! protein-DNA complex assembly +relationship: part_of GO:0032200 ! telomere organization +created_by: mah +creation_date: 2016-07-18T10:38:22Z + +[Term] +id: GO:1905325 +name: regulation of meiosis I spindle assembly checkpoint +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint." [GO_REF:0000058, GOC:TermGenie, PMID:26483559] +is_a: GO:0060631 ! regulation of meiosis I +is_a: GO:0090231 ! regulation of spindle checkpoint +is_a: GO:1902102 ! regulation of metaphase/anaphase transition of meiotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905318 ! meiosis I spindle assembly checkpoint +relationship: regulates GO:1905318 ! meiosis I spindle assembly checkpoint +created_by: mah +creation_date: 2016-07-20T12:48:40Z + +[Term] +id: GO:1905326 +name: positive regulation of meiosis I spindle assembly checkpoint +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint." [GO_REF:0000058, GOC:TermGenie, PMID:26483559] +synonym: "activation of meiosis I spindle assembly checkpoint" NARROW [GOC:TermGenie] +synonym: "up regulation of meiosis I spindle assembly checkpoint" EXACT [GOC:TermGenie] +synonym: "up-regulation of meiosis I spindle assembly checkpoint" EXACT [GOC:TermGenie] +synonym: "upregulation of meiosis I spindle assembly checkpoint" EXACT [GOC:TermGenie] +is_a: GO:0051446 ! positive regulation of meiotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:0090232 ! positive regulation of spindle checkpoint +is_a: GO:1905325 ! regulation of meiosis I spindle assembly checkpoint +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905318 ! meiosis I spindle assembly checkpoint +relationship: positively_regulates GO:1905318 ! meiosis I spindle assembly checkpoint +created_by: mah +creation_date: 2016-07-20T12:48:47Z + +[Term] +id: GO:1905327 +name: tracheoesophageal septum formation +namespace: biological_process +def: "The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:9731532] +synonym: "esophagotracheal septum formation" EXACT [GOC:TermGenie] +synonym: "tracheoesophageal ridges formation" RELATED [GOC:TermGenie] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +created_by: tb +creation_date: 2016-07-21T18:18:57Z + +[Term] +id: GO:1905328 +name: plant septum development +namespace: biological_process +def: "The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure." [GO_REF:0000080, GOC:tb, GOC:TermGenie, PMID:4562349] +synonym: "dissepiment development" BROAD [GOC:TermGenie] +is_a: GO:0048856 ! anatomical structure development +created_by: tb +creation_date: 2016-07-21T18:25:49Z + +[Term] +id: GO:1905329 +name: sphingoid long-chain base transport +namespace: biological_process +def: "The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast." [GO_REF:0000065, GOC:rn, GOC:TermGenie, PMID:27136724] +synonym: "dihydrosphingosine transport" NARROW [] +synonym: "long-chain base transport" RELATED [] +synonym: "phytosphingosine transport" NARROW [] +synonym: "sphingoid base(1+) transport" EXACT [] +synonym: "sphingoid transport" RELATED [] +synonym: "sphingosine transport" NARROW [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0015695 ! organic cation transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: tb +creation_date: 2016-07-22T01:40:59Z + +[Term] +id: GO:1905330 +name: regulation of morphogenesis of an epithelium +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002009 ! morphogenesis of an epithelium +relationship: regulates GO:0002009 ! morphogenesis of an epithelium +created_by: bhm +creation_date: 2016-07-22T07:13:49Z + +[Term] +id: GO:1905331 +name: negative regulation of morphogenesis of an epithelium +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +synonym: "inhibition of epithelium morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of morphogenesis of an epithelium" NARROW [GOC:TermGenie] +synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002009 ! morphogenesis of an epithelium +relationship: negatively_regulates GO:0002009 ! morphogenesis of an epithelium +created_by: bhm +creation_date: 2016-07-22T07:13:57Z + +[Term] +id: GO:1905332 +name: positive regulation of morphogenesis of an epithelium +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] +comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). +synonym: "activation of epithelium morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of morphogenesis of an epithelium" NARROW [GOC:TermGenie] +synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002009 ! morphogenesis of an epithelium +relationship: positively_regulates GO:0002009 ! morphogenesis of an epithelium +created_by: bhm +creation_date: 2016-07-22T07:14:05Z + +[Term] +id: GO:1905333 +name: regulation of gastric motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gastric motility." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:9924029] +is_a: GO:0044058 ! regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035482 ! gastric motility +relationship: regulates GO:0035482 ! gastric motility +created_by: als +creation_date: 2016-07-22T09:47:31Z + +[Term] +id: GO:1905334 +name: Swi5-Sfr1 complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Swi5-Sfr1 complex." [GOC:TermGenie, PMID:16921379] +synonym: "Sae3-Mei5 complex binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: al +creation_date: 2016-07-25T16:18:58Z + +[Term] +id: GO:1905335 +name: regulation of aggrephagy +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aggrephagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25686248] +is_a: GO:0016241 ! regulation of macroautophagy +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035973 ! aggrephagy +relationship: regulates GO:0035973 ! aggrephagy +created_by: pad +creation_date: 2016-07-26T13:41:46Z + +[Term] +id: GO:1905336 +name: negative regulation of aggrephagy +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25686248] +synonym: "down regulation of aggrephagy" EXACT [GOC:TermGenie] +synonym: "down-regulation of aggrephagy" EXACT [GOC:TermGenie] +synonym: "downregulation of aggrephagy" EXACT [GOC:TermGenie] +synonym: "inhibition of aggrephagy" NARROW [GOC:TermGenie] +is_a: GO:0016242 ! negative regulation of macroautophagy +is_a: GO:1905335 ! regulation of aggrephagy +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035973 ! aggrephagy +relationship: negatively_regulates GO:0035973 ! aggrephagy +created_by: pad +creation_date: 2016-07-26T13:41:54Z + +[Term] +id: GO:1905337 +name: positive regulation of aggrephagy +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aggrephagy." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25686248] +synonym: "activation of aggrephagy" NARROW [GOC:TermGenie] +synonym: "up regulation of aggrephagy" EXACT [GOC:TermGenie] +synonym: "up-regulation of aggrephagy" EXACT [GOC:TermGenie] +synonym: "upregulation of aggrephagy" EXACT [GOC:TermGenie] +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:1905335 ! regulation of aggrephagy +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035973 ! aggrephagy +relationship: positively_regulates GO:0035973 ! aggrephagy +created_by: pad +creation_date: 2016-07-26T13:42:02Z + +[Term] +id: GO:1905338 +name: negative regulation of cohesin unloading +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +synonym: "down regulation of cohesin unloading" EXACT [GOC:TermGenie] +synonym: "down-regulation of cohesin unloading" EXACT [GOC:TermGenie] +synonym: "downregulation of cohesin unloading" EXACT [GOC:TermGenie] +synonym: "inhibition of cohesin unloading" NARROW [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:0045876 ! positive regulation of sister chromatid cohesion +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1905343 ! regulation of cohesin unloading +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061774 ! cohesin unloading +relationship: negatively_regulates GO:0061774 ! cohesin unloading +created_by: vw +creation_date: 2016-07-26T16:23:58Z + +[Term] +id: GO:1905339 +name: positive regulation of cohesin unloading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cohesin unloading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +synonym: "activation of cohesin unloading" NARROW [GOC:TermGenie] +synonym: "up regulation of cohesin unloading" EXACT [GOC:TermGenie] +synonym: "up-regulation of cohesin unloading" EXACT [GOC:TermGenie] +synonym: "upregulation of cohesin unloading" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1905343 ! regulation of cohesin unloading +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061774 ! cohesin unloading +relationship: positively_regulates GO:0061774 ! cohesin unloading +created_by: vw +creation_date: 2016-07-26T16:24:06Z + +[Term] +id: GO:1905340 +name: regulation of protein localization to kinetochore +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to kinetochore." [GO_REF:0000058, GOC:TermGenie, PMID:22581055] +comment: Q9H211 in Human in PMID:22581055 +synonym: "regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034501 ! protein localization to kinetochore +relationship: regulates GO:0034501 ! protein localization to kinetochore +created_by: es +creation_date: 2016-07-27T15:26:36Z + +[Term] +id: GO:1905341 +name: negative regulation of protein localization to kinetochore +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore." [GO_REF:0000058, GOC:TermGenie, PMID:22581055] +comment: Q9H211 in Human in PMID:22581055 +synonym: "down regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "down regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +synonym: "down-regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "down-regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +synonym: "downregulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "downregulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +synonym: "inhibition of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to kinetochore" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "negative regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905340 ! regulation of protein localization to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034501 ! protein localization to kinetochore +relationship: negatively_regulates GO:0034501 ! protein localization to kinetochore +created_by: es +creation_date: 2016-07-27T15:26:44Z + +[Term] +id: GO:1905342 +name: positive regulation of protein localization to kinetochore +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore." [GO_REF:0000058, GOC:TermGenie, PMID:22581055] +comment: Q9H211 in Human in PMID:22581055 +synonym: "activation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to kinetochore" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "positive regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "up regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "up regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +synonym: "up-regulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "up-regulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +synonym: "upregulation of condensin localization to kinetochore" NARROW [GOC:TermGenie] +synonym: "upregulation of protein localisation to kinetochore" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to kinetochore" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905340 ! regulation of protein localization to kinetochore +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034501 ! protein localization to kinetochore +relationship: positively_regulates GO:0034501 ! protein localization to kinetochore +created_by: es +creation_date: 2016-07-27T15:26:51Z + +[Term] +id: GO:1905343 +name: regulation of cohesin unloading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cohesin unloading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0007063 ! regulation of sister chromatid cohesion +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061774 ! cohesin unloading +relationship: regulates GO:0061774 ! cohesin unloading +created_by: vw +creation_date: 2016-07-29T10:17:50Z + +[Term] +id: GO:1905344 +name: prostaglandin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of prostaglandin." [GO_REF:0000068, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25290914] +synonym: "prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "prostaglandin degradation" EXACT [GOC:TermGenie] +is_a: GO:0006693 ! prostaglandin metabolic process +is_a: GO:0062232 ! prostanoid catabolic process +created_by: rl +creation_date: 2016-07-31T08:20:02Z + +[Term] +id: GO:1905345 +name: protein localization to cleavage furrow +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cleavage furrow." [GO_REF:0000087, GOC:TermGenie, PMID:27082518] +synonym: "protein localisation in cleavage furrow" EXACT [GOC:TermGenie] +synonym: "protein localisation to cleavage furrow" EXACT [GOC:TermGenie] +synonym: "protein localization in cleavage furrow" EXACT [GOC:TermGenie] +is_a: GO:0072657 ! protein localization to membrane +is_a: GO:0072741 ! protein localization to cell division site +is_a: GO:1990778 ! protein localization to cell periphery +created_by: mah +creation_date: 2016-08-01T13:20:05Z + +[Term] +id: GO:1905346 +name: protein localization to cleavage furrow rim +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim." [GO_REF:0000087, GOC:TermGenie, PMID:27082518] +synonym: "protein localisation in cleavage furrow rim" EXACT [GOC:TermGenie] +synonym: "protein localisation to cleavage furrow rim" EXACT [GOC:TermGenie] +synonym: "protein localization in cleavage furrow rim" EXACT [GOC:TermGenie] +is_a: GO:1905345 ! protein localization to cleavage furrow +created_by: mah +creation_date: 2016-08-01T13:20:13Z + +[Term] +id: GO:1905347 +name: endodeoxyribonuclease complex +namespace: cellular_component +def: "A protein complex which is capable of endodeoxyribonuclease activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18413719] +comment: An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay). +synonym: "Mus81-Eme1 complex" NARROW [] +synonym: "Mus81-Eme2 complex" NARROW [] +is_a: GO:1905348 ! endonuclease complex +created_by: bhm +creation_date: 2016-08-03T12:20:12Z + +[Term] +id: GO:1905348 +name: endonuclease complex +namespace: cellular_component +def: "A protein complex which is capable of endonuclease activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18413719] +comment: An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay). +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2016-08-03T12:27:00Z + +[Term] +id: GO:1905349 +name: ciliary transition zone assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032] +synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie] +synonym: "cilial transition zone formation" EXACT [GOC:TermGenie] +synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie] +synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie] +synonym: "cilium transition zone formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +relationship: part_of GO:0060271 ! cilium assembly +created_by: pr +creation_date: 2016-08-04T14:49:43Z + +[Term] +id: GO:1905350 +name: Y-shaped link assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:23728985, PMID:24664739, PMID:26595381, PMID:4554367] +synonym: "membrane-microtubule complex assembly" RELATED [GOC:TermGenie] +synonym: "membrane-microtubule complex formation" RELATED [GOC:TermGenie] +synonym: "Y-link assembly" RELATED [GOC:TermGenie] +synonym: "Y-link formation" RELATED [GOC:TermGenie] +synonym: "Y-link structure assembly" RELATED [GOC:TermGenie] +synonym: "Y-link structure formation" RELATED [GOC:TermGenie] +synonym: "Y-shaped assemblage assembly" RELATED [GOC:TermGenie] +synonym: "Y-shaped assemblage formation" RELATED [GOC:TermGenie] +synonym: "Y-shaped fiber assembly" RELATED [GOC:TermGenie] +synonym: "Y-shaped fiber formation" RELATED [GOC:TermGenie] +synonym: "Y-shaped fibre assembly" RELATED [GOC:TermGenie] +synonym: "Y-shaped fibre formation" RELATED [GOC:TermGenie] +synonym: "Y-shaped link formation" EXACT [GOC:TermGenie] +synonym: "Y-shaped linker assembly" RELATED [GOC:TermGenie] +synonym: "Y-shaped linker formation" RELATED [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pr +creation_date: 2016-08-04T16:04:26Z + +[Term] +id: GO:1905351 +name: pericyte cell migration +namespace: biological_process +def: "The orderly movement of a pericyte cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26268439] +is_a: GO:0016477 ! cell migration +created_by: rph +creation_date: 2016-08-05T12:01:48Z + +[Term] +id: GO:1905352 +name: ciliary necklace assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:20399632, PMID:6409906] +synonym: "cilial necklace assembly" EXACT [GOC:TermGenie] +synonym: "cilial necklace formation" EXACT [GOC:TermGenie] +synonym: "ciliary necklace formation" EXACT [GOC:TermGenie] +synonym: "cilium necklace assembly" EXACT [GOC:TermGenie] +synonym: "cilium necklace formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pr +creation_date: 2016-08-05T14:01:23Z + +[Term] +id: GO:1905353 +name: ciliary transition fiber assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:24189274] +synonym: "centriolar distal appendage assembly" RELATED [GOC:TermGenie] +synonym: "centriolar distal appendage formation" RELATED [GOC:TermGenie] +synonym: "cilial transition fiber assembly" EXACT [GOC:TermGenie] +synonym: "cilial transition fiber formation" EXACT [GOC:TermGenie] +synonym: "cilial transition fibre assembly" EXACT [GOC:TermGenie] +synonym: "cilial transition fibre formation" EXACT [GOC:TermGenie] +synonym: "ciliary transition fiber formation" EXACT [GOC:TermGenie] +synonym: "ciliary transition fibre assembly" EXACT [GOC:TermGenie] +synonym: "ciliary transition fibre formation" EXACT [GOC:TermGenie] +synonym: "cilium transition fiber assembly" EXACT [GOC:TermGenie] +synonym: "cilium transition fiber formation" EXACT [GOC:TermGenie] +synonym: "cilium transition fibre assembly" EXACT [GOC:TermGenie] +synonym: "cilium transition fibre formation" EXACT [GOC:TermGenie] +synonym: "distal appendage of basal body assembly" RELATED [GOC:TermGenie] +synonym: "distal appendage of basal body formation" RELATED [GOC:TermGenie] +synonym: "distal appendage of centriole assembly" RELATED [GOC:TermGenie] +synonym: "distal appendage of centriole formation" RELATED [GOC:TermGenie] +synonym: "distal appendage of mother centriole assembly" RELATED [GOC:TermGenie] +synonym: "distal appendage of mother centriole formation" RELATED [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pr +creation_date: 2016-08-05T14:01:32Z + +[Term] +id: GO:1905354 +name: exoribonuclease complex +namespace: cellular_component +def: "A protein complex which is capable of exoribonuclease activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:17174896] +comment: An example of this is DIS3 in human (Q9Y2L1) in PMID:17174896 (inferred from direct assay). +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-08-08T10:18:29Z + +[Term] +id: GO:1905355 +name: spine apparatus assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a spine apparatus." [GO_REF:0000079, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:12928494] +synonym: "dense material assembly" NARROW [GOC:TermGenie] +synonym: "dense material formation" NARROW [GOC:TermGenie] +synonym: "spine apparatus formation" EXACT [GOC:TermGenie] +is_a: GO:0070925 ! organelle assembly +created_by: bf +creation_date: 2016-08-09T10:12:29Z + +[Term] +id: GO:1905356 +name: regulation of snRNA pseudouridine synthesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis." [GO_REF:0000058, GOC:TermGenie, PMID:27268497] +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031120 ! snRNA pseudouridine synthesis +relationship: regulates GO:0031120 ! snRNA pseudouridine synthesis +created_by: se +creation_date: 2016-08-09T19:12:27Z + +[Term] +id: GO:1905357 +name: negative regulation of snRNA pseudouridine synthesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis." [GO_REF:0000058, GOC:TermGenie, PMID:27268497] +synonym: "down regulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of snRNA pseudouridine synthesis" NARROW [GOC:TermGenie] +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:1905356 ! regulation of snRNA pseudouridine synthesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031120 ! snRNA pseudouridine synthesis +relationship: negatively_regulates GO:0031120 ! snRNA pseudouridine synthesis +created_by: se +creation_date: 2016-08-09T19:12:35Z + +[Term] +id: GO:1905358 +name: positive regulation of snRNA pseudouridine synthesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis." [GO_REF:0000058, GOC:TermGenie, PMID:27268497] +synonym: "activation of snRNA pseudouridine synthesis" NARROW [GOC:TermGenie] +synonym: "up regulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of snRNA pseudouridine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:1905356 ! regulation of snRNA pseudouridine synthesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031120 ! snRNA pseudouridine synthesis +relationship: positively_regulates GO:0031120 ! snRNA pseudouridine synthesis +created_by: se +creation_date: 2016-08-09T19:12:42Z + +[Term] +id: GO:1905359 +name: protein localization to meiotic spindle +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a meiotic spindle." [GO_REF:0000087, GOC:TermGenie, PMID:26696398] +synonym: "protein localisation to meiotic spindle" EXACT [GOC:TermGenie] +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +created_by: mah +creation_date: 2016-08-10T14:49:03Z + +[Term] +id: GO:1905360 +name: GTPase complex +namespace: cellular_component +def: "A protein complex which is capable of GTPase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:9178006] +comment: An example of this is HRAS in human (P01112) in PMID:9178006 (inferred from direct assay). +synonym: "HRAS-SOS1 complex" NARROW [] +synonym: "RASH-SOS1 complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-08-11T15:34:44Z + +[Term] +id: GO:1905362 +name: negative regulation of endosomal vesicle fusion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "down regulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "down regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "inhibition of endosomal vesicle fusion" NARROW [GOC:TermGenie] +synonym: "inhibition of endosome vesicle fusion" NARROW [GOC:TermGenie] +synonym: "negative regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +is_a: GO:0031339 ! negative regulation of vesicle fusion +is_a: GO:1905364 ! regulation of endosomal vesicle fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034058 ! endosomal vesicle fusion +relationship: negatively_regulates GO:0034058 ! endosomal vesicle fusion +created_by: bc +creation_date: 2016-08-16T11:40:44Z + +[Term] +id: GO:1905363 +name: positive regulation of endosomal vesicle fusion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "activation of endosomal vesicle fusion" NARROW [GOC:TermGenie] +synonym: "activation of endosome vesicle fusion" NARROW [GOC:TermGenie] +synonym: "positive regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of endosomal vesicle fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +is_a: GO:0031340 ! positive regulation of vesicle fusion +is_a: GO:1905364 ! regulation of endosomal vesicle fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034058 ! endosomal vesicle fusion +relationship: positively_regulates GO:0034058 ! endosomal vesicle fusion +created_by: bc +creation_date: 2016-08-16T11:40:51Z + +[Term] +id: GO:1905364 +name: regulation of endosomal vesicle fusion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endosomal vesicle fusion." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "regulation of endosome vesicle fusion" EXACT [GOC:TermGenie] +is_a: GO:0031338 ! regulation of vesicle fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034058 ! endosomal vesicle fusion +relationship: regulates GO:0034058 ! endosomal vesicle fusion +created_by: bc +creation_date: 2016-08-16T11:40:36Z + +[Term] +id: GO:1905365 +name: regulation of intralumenal vesicle formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intralumenal vesicle formation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "regulation of endosome membrane budding" EXACT [GOC:TermGenie] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1904978 ! regulation of endosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070676 ! intralumenal vesicle formation +relationship: regulates GO:0070676 ! intralumenal vesicle formation +created_by: bc +creation_date: 2016-08-16T12:00:01Z + +[Term] +id: GO:1905366 +name: negative regulation of intralumenal vesicle formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "down regulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "down regulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "down-regulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "downregulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +synonym: "inhibition of endosome membrane budding" NARROW [GOC:TermGenie] +synonym: "inhibition of intralumenal vesicle formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of endosome membrane budding" EXACT [GOC:TermGenie] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:1904979 ! negative regulation of endosome organization +is_a: GO:1905365 ! regulation of intralumenal vesicle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070676 ! intralumenal vesicle formation +relationship: negatively_regulates GO:0070676 ! intralumenal vesicle formation +created_by: bc +creation_date: 2016-08-16T12:00:09Z + +[Term] +id: GO:1905367 +name: positive regulation of intralumenal vesicle formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "activation of endosome membrane budding" NARROW [GOC:TermGenie] +synonym: "activation of intralumenal vesicle formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "up regulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "up regulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "up-regulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of endosome membrane budding" EXACT [GOC:TermGenie] +synonym: "upregulation of intralumenal vesicle formation" EXACT [GOC:TermGenie] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:1904980 ! positive regulation of endosome organization +is_a: GO:1905365 ! regulation of intralumenal vesicle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070676 ! intralumenal vesicle formation +relationship: positively_regulates GO:0070676 ! intralumenal vesicle formation +created_by: bc +creation_date: 2016-08-16T12:00:16Z + +[Term] +id: GO:1905368 +name: peptidase complex +namespace: cellular_component +def: "A protein complex which is capable of peptidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] +comment: An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay). +synonym: "protease complex" EXACT [] +synonym: "tryptase complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-08-16T12:49:36Z + +[Term] +id: GO:1905369 +name: endopeptidase complex +namespace: cellular_component +def: "A protein complex which is capable of endopeptidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] +comment: An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay). +is_a: GO:1905368 ! peptidase complex +created_by: bhm +creation_date: 2016-08-16T12:52:16Z + +[Term] +id: GO:1905370 +name: serine-type endopeptidase complex +namespace: cellular_component +def: "A protein complex which is capable of serine-type endopeptidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] +comment: An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay). +is_a: GO:1905286 ! serine-type peptidase complex +is_a: GO:1905369 ! endopeptidase complex +created_by: bhm +creation_date: 2016-08-16T13:09:57Z + +[Term] +id: GO:1905371 +name: ceramide phosphoethanolamine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving ceramide phosphoethanolamine." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:25667419] +synonym: "ceramide phosphoethanolamine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006644 ! phospholipid metabolic process +is_a: GO:0006665 ! sphingolipid metabolic process +created_by: hjd +creation_date: 2016-08-16T17:10:56Z + +[Term] +id: GO:1905372 +name: ceramide phosphoethanolamine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:25667419] +synonym: "ceramide phosphoethanolamine breakdown" EXACT [GOC:TermGenie] +synonym: "ceramide phosphoethanolamine catabolism" EXACT [GOC:TermGenie] +synonym: "ceramide phosphoethanolamine degradation" EXACT [GOC:TermGenie] +is_a: GO:0009395 ! phospholipid catabolic process +is_a: GO:0030149 ! sphingolipid catabolic process +is_a: GO:1905371 ! ceramide phosphoethanolamine metabolic process +created_by: hjd +creation_date: 2016-08-16T17:11:04Z + +[Term] +id: GO:1905373 +name: ceramide phosphoethanolamine biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine." [GO_REF:0000068, GOC:hjd, GOC:TermGenie, PMID:25667419] +synonym: "ceramide phosphoethanolamine anabolism" EXACT [GOC:TermGenie] +synonym: "ceramide phosphoethanolamine biosynthesis" EXACT [GOC:TermGenie] +synonym: "ceramide phosphoethanolamine formation" EXACT [GOC:TermGenie] +synonym: "ceramide phosphoethanolamine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0008654 ! phospholipid biosynthetic process +is_a: GO:0030148 ! sphingolipid biosynthetic process +is_a: GO:1905371 ! ceramide phosphoethanolamine metabolic process +created_by: hjd +creation_date: 2016-08-16T17:11:12Z + +[Term] +id: GO:1905374 +name: response to homocysteine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26722473] +synonym: "response to 2-amino-4-mercaptobutyric acid" EXACT [] +synonym: "response to 2-amino-4-sulfanylbutanoic acid" EXACT [] +synonym: "response to Hcy" EXACT [] +is_a: GO:0043200 ! response to amino acid +created_by: sl +creation_date: 2016-08-17T20:17:53Z + +[Term] +id: GO:1905375 +name: cellular response to homocysteine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26722473] +synonym: "cellular response to 2-amino-4-mercaptobutyric acid" EXACT [] +synonym: "cellular response to 2-amino-4-sulfanylbutanoic acid" EXACT [] +synonym: "cellular response to Hcy" EXACT [] +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1905374 ! response to homocysteine +created_by: sl +creation_date: 2016-08-17T20:18:00Z + +[Term] +id: GO:1905376 +name: negative regulation of cytochrome-c oxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26722473] +synonym: "down regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "down regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "down regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "down regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "down regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "down regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "down regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "down regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "down-regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "down-regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "down-regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "down-regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "down-regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "downregulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "downregulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "downregulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "downregulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "downregulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "downregulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "downregulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "downregulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "inhibition of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "inhibition of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytochrome c oxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "inhibition of cytochrome-c oxidase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "inhibition of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of indophenolase" NARROW [GOC:TermGenie] +synonym: "inhibition of NADH cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "inhibition of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] +synonym: "negative regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] +synonym: "negative regulation of indophenol oxidase" NARROW [GOC:TermGenie] +synonym: "negative regulation of indophenolase" NARROW [GOC:TermGenie] +synonym: "negative regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] +synonym: "negative regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1904733 ! negative regulation of electron transfer activity +is_a: GO:1904959 ! regulation of cytochrome-c oxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004129 ! cytochrome-c oxidase activity +relationship: negatively_regulates GO:0004129 ! cytochrome-c oxidase activity +created_by: sl +creation_date: 2016-08-17T20:29:57Z + +[Term] +id: GO:1905377 +name: response to D-galactose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26261574] +synonym: "response to D-Gal" EXACT [] +synonym: "response to D-galacto-hexose" EXACT [] +is_a: GO:0009746 ! response to hexose +created_by: sl +creation_date: 2016-08-17T22:17:25Z + +[Term] +id: GO:1905378 +name: cellular response to D-galactose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:26261574] +synonym: "cellular response to D-Gal" EXACT [] +synonym: "cellular response to D-galacto-hexose" EXACT [] +is_a: GO:0071331 ! cellular response to hexose stimulus +is_a: GO:1905377 ! response to D-galactose +created_by: sl +creation_date: 2016-08-17T22:17:32Z + +[Term] +id: GO:1905379 +name: beta-N-acetylhexosaminidase complex +namespace: cellular_component +def: "A protein complex which is capable of beta-N-acetylhexosaminidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:6458607] +comment: An example of this is HEXB in human (UniProt symbol P07686) in PMID:6458607 (inferred from direct assay). +synonym: "HEX A complex" NARROW [] +synonym: "HEX B complex" NARROW [] +synonym: "HEX S complex" NARROW [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2016-08-18T08:26:15Z + +[Term] +id: GO:1905380 +name: regulation of snRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:10022900] +synonym: "regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "regulation of snRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042795 ! snRNA transcription by RNA polymerase II +relationship: regulates GO:0042795 ! snRNA transcription by RNA polymerase II +created_by: bhm +creation_date: 2016-08-18T13:39:20Z + +[Term] +id: GO:1905381 +name: negative regulation of snRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:10022900] +synonym: "down regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "down regulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "down-regulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "downregulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "inhibition of snRNA transcription from Pol II promoter" NARROW [GOC:TermGenie] +synonym: "inhibition of snRNA transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "negative regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "negative regulation of snRNA transcription from RNA polymerase II promoter" EXACT [] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +is_a: GO:1905380 ! regulation of snRNA transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042795 ! snRNA transcription by RNA polymerase II +relationship: negatively_regulates GO:0042795 ! snRNA transcription by RNA polymerase II +created_by: bhm +creation_date: 2016-08-18T13:39:27Z + +[Term] +id: GO:1905382 +name: positive regulation of snRNA transcription by RNA polymerase II +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:10022900] +comment: An example of this is GTF2A1 in human (UniProt symbol P52655) in PMID:10022900 (inferred from direct assay). +synonym: "activation of snRNA transcription from Pol II promoter" NARROW [GOC:TermGenie] +synonym: "activation of snRNA transcription from RNA polymerase II promoter" NARROW [GOC:TermGenie] +synonym: "positive regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "positive regulation of snRNA transcription from RNA polymerase II promoter" EXACT [] +synonym: "up regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up regulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "up-regulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of snRNA transcription from Pol II promoter" EXACT [GOC:TermGenie] +synonym: "upregulation of snRNA transcription from RNA polymerase II promoter" EXACT [GOC:TermGenie] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:1905380 ! regulation of snRNA transcription by RNA polymerase II +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042795 ! snRNA transcription by RNA polymerase II +relationship: positively_regulates GO:0042795 ! snRNA transcription by RNA polymerase II +created_by: bhm +creation_date: 2016-08-18T13:39:34Z + +[Term] +id: GO:1905383 +name: protein localization to presynapse +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494] +synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494] +is_a: GO:0035418 ! protein localization to synapse +created_by: dos +creation_date: 2016-08-18T14:42:59Z + +[Term] +id: GO:1905384 +name: regulation of protein localization to presynapse +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] +synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +is_a: GO:1902473 ! regulation of protein localization to synapse +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905383 ! protein localization to presynapse +relationship: regulates GO:1905383 ! protein localization to presynapse +created_by: dos +creation_date: 2016-08-18T14:56:00Z + +[Term] +id: GO:1905385 +name: negative regulation of protein localization to presynapse +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] +synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in presynapse" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to presynapse" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in presynapse" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to presynapse" NARROW [GOC:TermGenie] +synonym: "inhibition of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1905384 ! regulation of protein localization to presynapse +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905383 ! protein localization to presynapse +relationship: negatively_regulates GO:1905383 ! protein localization to presynapse +created_by: dos +creation_date: 2016-08-18T14:56:08Z + +[Term] +id: GO:1905386 +name: positive regulation of protein localization to presynapse +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] +synonym: "activation of protein localisation in presynapse" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to presynapse" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in presynapse" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to presynapse" NARROW [GOC:TermGenie] +synonym: "activation of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie] +synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] +is_a: GO:1902474 ! positive regulation of protein localization to synapse +is_a: GO:1905384 ! regulation of protein localization to presynapse +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905383 ! protein localization to presynapse +relationship: positively_regulates GO:1905383 ! protein localization to presynapse +created_by: dos +creation_date: 2016-08-18T14:56:21Z + +[Term] +id: GO:1905387 +name: response to beta-carotene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16771696] +synonym: "response to beta,beta-carotene" EXACT [] +is_a: GO:0033993 ! response to lipid +created_by: sl +creation_date: 2016-08-18T16:18:24Z + +[Term] +id: GO:1905388 +name: cellular response to beta-carotene +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16771696] +synonym: "cellular response to beta,beta-carotene" EXACT [] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1905387 ! response to beta-carotene +created_by: sl +creation_date: 2016-08-18T16:18:31Z + +[Term] +id: GO:1905389 +name: response to leukotriene B4 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14656734] +synonym: "response to LTB4" EXACT [] +is_a: GO:0070542 ! response to fatty acid +created_by: sl +creation_date: 2016-08-18T16:37:24Z + +[Term] +id: GO:1905390 +name: cellular response to leukotriene B4 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14656734] +synonym: "cellular response to LTB4" EXACT [] +is_a: GO:0071398 ! cellular response to fatty acid +is_a: GO:1905389 ! response to leukotriene B4 +created_by: sl +creation_date: 2016-08-18T16:37:31Z + +[Term] +id: GO:1905391 +name: regulation of protein localization to cell division site involved in cell separation after cytokinesis +namespace: biological_process +def: "Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis." [GO_REF:0000060, GOC:TermGenie, PMID:25411334] +synonym: "regulation of protein localisation to cell division site involved in cell separation after cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to cell division site involved in cell separation following cytokinesis" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to cell division site involved in cytokinetic cell separation" RELATED [GOC:TermGenie] +synonym: "regulation of protein localisation to cell division site involved in mitotic cytokinetic cell separation" EXACT [GOC:TermGenie] +is_a: GO:1901900 ! regulation of protein localization to cell division site +intersection_of: GO:1901900 ! regulation of protein localization to cell division site +intersection_of: part_of GO:0000920 ! septum digestion after cytokinesis +relationship: part_of GO:0000920 ! septum digestion after cytokinesis +created_by: vw +creation_date: 2016-08-22T09:40:47Z + +[Term] +id: GO:1905392 +name: plant organ morphogenesis +namespace: biological_process +def: "The developmental process by which a plant organ is generated and organized." [GO_REF:0000083, GOC:tb, GOC:TermGenie] +is_a: GO:0009653 ! anatomical structure morphogenesis +relationship: part_of GO:0099402 ! plant organ development +created_by: tb +creation_date: 2016-08-24T00:21:19Z + +[Term] +id: GO:1905393 +name: plant organ formation +namespace: biological_process +def: "The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:tb, GOC:TermGenie] +is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis +created_by: tb +creation_date: 2016-08-24T00:21:27Z + +[Term] +id: GO:1905394 +name: retromer complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a retromer complex." [GOC:bc, GOC:PARL, GOC:TermGenie, PMID:27385586] +is_a: GO:0044877 ! protein-containing complex binding +created_by: bc +creation_date: 2016-08-24T14:00:32Z + +[Term] +id: GO:1905395 +name: response to flavonoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22700048] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2016-08-24T15:00:54Z + +[Term] +id: GO:1905396 +name: cellular response to flavonoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22700048] +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905395 ! response to flavonoid +created_by: sl +creation_date: 2016-08-24T15:01:02Z + +[Term] +id: GO:1905397 +name: activated CD8-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an activated CD8-positive, alpha-beta T cell." [GO_REF:0000085, GOC:TermGenie, PMID:24187568] +synonym: "activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070231 ! T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T08:09:27Z + +[Term] +id: GO:1905398 +name: activated CD4-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an activated CD4-positive, alpha-beta T cell." [GO_REF:0000085, GOC:TermGenie, PMID:24187568] +synonym: "activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070231 ! T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T08:13:40Z + +[Term] +id: GO:1905399 +name: regulation of activated CD4-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +relationship: regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:09:46Z + +[Term] +id: GO:1905400 +name: negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "down regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T-cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070233 ! negative regulation of T cell apoptotic process +is_a: GO:1905399 ! regulation of activated CD4-positive, alpha-beta T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +relationship: negatively_regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:09:53Z + +[Term] +id: GO:1905401 +name: positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "activation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T-cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070234 ! positive regulation of T cell apoptotic process +is_a: GO:1905399 ! regulation of activated CD4-positive, alpha-beta T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +relationship: positively_regulates GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:10:00Z + +[Term] +id: GO:1905402 +name: regulation of activated CD8-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070232 ! regulation of T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +relationship: regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:13:56Z + +[Term] +id: GO:1905403 +name: negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "down regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T-cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070233 ! negative regulation of T cell apoptotic process +is_a: GO:1905402 ! regulation of activated CD8-positive, alpha-beta T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +relationship: negatively_regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:14:03Z + +[Term] +id: GO:1905404 +name: positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24187568] +synonym: "activation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T-cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T-cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T-cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0070234 ! positive regulation of T cell apoptotic process +is_a: GO:1905402 ! regulation of activated CD8-positive, alpha-beta T cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +relationship: positively_regulates GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process +created_by: pga +creation_date: 2016-08-25T09:14:10Z + +[Term] +id: GO:1905405 +name: regulation of mitotic cohesin loading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cohesin loading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation +is_a: GO:0071922 ! regulation of cohesin loading +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061780 ! mitotic cohesin loading +relationship: regulates GO:0061780 ! mitotic cohesin loading +created_by: vw +creation_date: 2016-08-25T14:48:46Z + +[Term] +id: GO:1905406 +name: positive regulation of mitotic cohesin loading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0062033 ! positive regulation of mitotic sister chromatid segregation +is_a: GO:1905309 ! positive regulation of cohesin loading +is_a: GO:1905405 ! regulation of mitotic cohesin loading +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061780 ! mitotic cohesin loading +relationship: positively_regulates GO:0061780 ! mitotic cohesin loading +created_by: vw +creation_date: 2016-08-25T14:49:01Z + +[Term] +id: GO:1905407 +name: regulation of creatine transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25531585] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:1903959 ! regulation of anion transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005308 ! creatine transmembrane transporter activity +relationship: regulates GO:0005308 ! creatine transmembrane transporter activity +created_by: bc +creation_date: 2016-08-25T15:08:48Z + +[Term] +id: GO:1905408 +name: negative regulation of creatine transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25531585] +synonym: "down regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "downregulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "inhibition of creatine transmembrane transporter activity" NARROW [GOC:TermGenie] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:0032891 ! negative regulation of organic acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1905407 ! regulation of creatine transmembrane transporter activity +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005308 ! creatine transmembrane transporter activity +relationship: negatively_regulates GO:0005308 ! creatine transmembrane transporter activity +created_by: bc +creation_date: 2016-08-25T15:08:56Z + +[Term] +id: GO:1905409 +name: positive regulation of creatine transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25531585] +synonym: "activation of creatine transmembrane transporter activity" NARROW [GOC:TermGenie] +synonym: "up regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +synonym: "upregulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:0032892 ! positive regulation of organic acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1905407 ! regulation of creatine transmembrane transporter activity +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005308 ! creatine transmembrane transporter activity +relationship: positively_regulates GO:0005308 ! creatine transmembrane transporter activity +created_by: bc +creation_date: 2016-08-25T15:09:04Z + +[Term] +id: GO:1905410 +name: regulation of mitotic cohesin unloading +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic cohesin unloading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:1905343 ! regulation of cohesin unloading +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061781 ! mitotic cohesin unloading +relationship: regulates GO:0061781 ! mitotic cohesin unloading +created_by: vw +creation_date: 2016-08-25T15:45:22Z + +[Term] +id: GO:1905411 +name: positive regulation of mitotic cohesin unloading +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:1905339 ! positive regulation of cohesin unloading +is_a: GO:1905410 ! regulation of mitotic cohesin unloading +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061781 ! mitotic cohesin unloading +relationship: positively_regulates GO:0061781 ! mitotic cohesin unloading +created_by: vw +creation_date: 2016-08-25T15:45:30Z + +[Term] +id: GO:1905412 +name: negative regulation of mitotic cohesin loading +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading." [GO_REF:0000058, GOC:TermGenie, PMID:26687354] +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:0071923 ! negative regulation of cohesin loading +is_a: GO:1905405 ! regulation of mitotic cohesin loading +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061780 ! mitotic cohesin loading +relationship: negatively_regulates GO:0061780 ! mitotic cohesin loading +created_by: vw +creation_date: 2016-08-27T15:24:35Z + +[Term] +id: GO:1905413 +name: regulation of dense core granule exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dense core granule exocytosis." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18468511] +synonym: "regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: occurs_in GO:0098793 ! presynapse +intersection_of: regulates GO:1990504 ! dense core granule exocytosis +relationship: occurs_in GO:0098793 ! presynapse +relationship: regulates GO:1990504 ! dense core granule exocytosis +created_by: bf +creation_date: 2016-08-31T08:02:21Z + +[Term] +id: GO:1905414 +name: negative regulation of dense core granule exocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of dense core granule exocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of dense core vesicle exocytosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +is_a: GO:0045955 ! negative regulation of calcium ion-dependent exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990504 ! dense core granule exocytosis +relationship: negatively_regulates GO:1990504 ! dense core granule exocytosis +created_by: bf +creation_date: 2016-08-31T08:02:28Z + +[Term] +id: GO:1905415 +name: positive regulation of dense core granule exocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18468511] +synonym: "activation of dense core granule exocytosis" NARROW [GOC:TermGenie] +synonym: "activation of dense core vesicle exocytosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of dense core granule exocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of dense core vesicle exocytosis" EXACT [GOC:TermGenie] +is_a: GO:0045956 ! positive regulation of calcium ion-dependent exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990504 ! dense core granule exocytosis +relationship: positively_regulates GO:1990504 ! dense core granule exocytosis +created_by: bf +creation_date: 2016-08-31T08:02:36Z + +[Term] +id: GO:1905416 +name: regulation of amoeboid sperm motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amoeboid sperm motility." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie] +synonym: "regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +is_a: GO:2000145 ! regulation of cell motility +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097723 ! amoeboid sperm motility +relationship: regulates GO:0097723 ! amoeboid sperm motility +created_by: pr +creation_date: 2016-09-01T11:28:48Z + +[Term] +id: GO:1905417 +name: negative regulation of amoeboid sperm motility +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie] +synonym: "down regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "down regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "down regulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "down regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "down-regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "down-regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "down-regulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "down-regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "downregulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "downregulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "downregulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "downregulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "inhibition of ameboid sperm motility" NARROW [GOC:TermGenie] +synonym: "inhibition of ameboid sperm movement" NARROW [GOC:TermGenie] +synonym: "inhibition of amoeboid sperm motility" NARROW [GOC:TermGenie] +synonym: "inhibition of amoeboid sperm movement" NARROW [GOC:TermGenie] +synonym: "negative regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "negative regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "negative regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +is_a: GO:1905416 ! regulation of amoeboid sperm motility +is_a: GO:2000146 ! negative regulation of cell motility +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097723 ! amoeboid sperm motility +relationship: negatively_regulates GO:0097723 ! amoeboid sperm motility +created_by: pr +creation_date: 2016-09-01T11:28:55Z + +[Term] +id: GO:1905418 +name: positive regulation of amoeboid sperm motility +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie] +synonym: "activation of ameboid sperm motility" NARROW [GOC:TermGenie] +synonym: "activation of ameboid sperm movement" NARROW [GOC:TermGenie] +synonym: "activation of amoeboid sperm motility" NARROW [GOC:TermGenie] +synonym: "activation of amoeboid sperm movement" NARROW [GOC:TermGenie] +synonym: "positive regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "positive regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "positive regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "up regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "up regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "up regulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "up regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "up-regulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "up-regulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "up-regulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "up-regulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +synonym: "upregulation of ameboid sperm motility" EXACT [GOC:TermGenie] +synonym: "upregulation of ameboid sperm movement" EXACT [GOC:TermGenie] +synonym: "upregulation of amoeboid sperm motility" EXACT [GOC:TermGenie] +synonym: "upregulation of amoeboid sperm movement" EXACT [GOC:TermGenie] +is_a: GO:1905416 ! regulation of amoeboid sperm motility +is_a: GO:2000147 ! positive regulation of cell motility +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097723 ! amoeboid sperm motility +relationship: positively_regulates GO:0097723 ! amoeboid sperm motility +created_by: pr +creation_date: 2016-09-01T11:29:03Z + +[Term] +id: GO:1905419 +name: sperm flagellum movement involved in flagellated sperm motility +namespace: biological_process +alt_id: GO:0097724 +def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031] +synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc] +synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie] +is_a: GO:0022414 ! reproductive process +is_a: GO:0060294 ! cilium movement involved in cell motility +intersection_of: GO:0003341 ! cilium movement +intersection_of: part_of GO:0030317 ! flagellated sperm motility +relationship: part_of GO:0030317 ! flagellated sperm motility +created_by: krc +creation_date: 2016-09-01T17:52:39Z + +[Term] +id: GO:1905420 +name: vascular smooth muscle cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any vascular smooth muscle cell differentiation that is involved in phenotypic switching." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:0035886 ! vascular smooth muscle cell differentiation +is_a: GO:0090679 ! cell differentiation involved in phenotypic switching +intersection_of: GO:0035886 ! vascular smooth muscle cell differentiation +intersection_of: part_of GO:0090677 ! reversible differentiation +created_by: rph +creation_date: 2016-09-05T12:43:46Z + +[Term] +id: GO:1905421 +name: regulation of plant organ morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plant organ morphogenesis." [GO_REF:0000058, GOC:tb, GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905392 ! plant organ morphogenesis +relationship: regulates GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-09-06T23:00:14Z + +[Term] +id: GO:1905422 +name: negative regulation of plant organ morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis." [GO_REF:0000058, GOC:tb, GOC:TermGenie] +synonym: "down regulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of plant organ morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905421 ! regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905392 ! plant organ morphogenesis +relationship: negatively_regulates GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-09-06T23:00:22Z + +[Term] +id: GO:1905423 +name: positive regulation of plant organ morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis." [GO_REF:0000058, GOC:tb, GOC:TermGenie] +synonym: "activation of plant organ morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of plant organ morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905421 ! regulation of plant organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905392 ! plant organ morphogenesis +relationship: positively_regulates GO:1905392 ! plant organ morphogenesis +created_by: tb +creation_date: 2016-09-06T23:00:29Z + +[Term] +id: GO:1905424 +name: regulation of Wnt-mediated midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17244647] +synonym: "regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of midbrain dopaminergic neuron differentiation by regulation of Wnt signaling" RELATED [GOC:bf] +synonym: "regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:bf] +synonym: "regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +is_a: GO:1904956 ! regulation of midbrain dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +relationship: regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-09-07T10:03:36Z + +[Term] +id: GO:1905425 +name: negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "down regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "down-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "down-regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "downregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "downregulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "inhibition of Wnt-mediated midbrain DA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling" RELATED [GOC:bf] +synonym: "negative regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:bf] +synonym: "negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "negative regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:1904957 ! negative regulation of midbrain dopaminergic neuron differentiation +is_a: GO:1905424 ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +relationship: negatively_regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-09-07T10:03:44Z + +[Term] +id: GO:1905426 +name: positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:17244647] +synonym: "activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wg signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wg signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wg signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wg signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wg signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wg signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signalling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" NARROW [GOC:TermGenie] +synonym: "activation of Wnt signaling pathway involved in mDA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt signaling pathway involved in midbrain DA neurogenesis" NARROW [GOC:TermGenie] +synonym: "activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" NARROW [GOC:TermGenie] +synonym: "activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" NARROW [GOC:TermGenie] +synonym: "activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "activation of Wnt-mediated midbrain DA neuron differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling" RELATED [GOC:bf] +synonym: "positive regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:bf] +synonym: "positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "positive regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "up regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "up-regulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" RELATED [GOC:TermGenie] +synonym: "upregulation of Wnt-mediated midbrain DA neuron differentiation" EXACT [GOC:TermGenie] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:1904958 ! positive regulation of midbrain dopaminergic neuron differentiation +is_a: GO:1905424 ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +relationship: positively_regulates GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +created_by: bf +creation_date: 2016-09-07T10:03:51Z + +[Term] +id: GO:1905427 +name: intracellular signal transduction involved in positive regulation of cell growth +namespace: biological_process +def: "Any intracellular signal transduction that is involved in positive regulation of cell growth." [GO_REF:0000060, GOC:al, GOC:TermGenie, GOC:vw, PMID:15917811] +synonym: "intracellular protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction involved in up regulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction involved in up-regulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction involved in upregulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in positive regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in up regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in up-regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signal transduction pathway involved in upregulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling chain involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signaling chain involved in positive regulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "intracellular signaling chain involved in up regulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in up-regulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signaling chain involved in upregulation of cell growth" EXACT [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in activation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in positive regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in stimulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in up regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in up-regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "intracellular signaling pathway involved in upregulation of cell growth" RELATED [GOC:TermGenie] +synonym: "protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transduction via intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in activation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] +synonym: "signal transmission via intracellular cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] +is_a: GO:0035556 ! intracellular signal transduction +intersection_of: GO:0035556 ! intracellular signal transduction +intersection_of: part_of GO:0030307 ! positive regulation of cell growth +relationship: part_of GO:0030307 ! positive regulation of cell growth +created_by: dph +creation_date: 2016-09-07T18:15:01Z + +[Term] +id: GO:1905428 +name: regulation of plant organ formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plant organ formation." [GO_REF:0000058, GOC:tb, GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905393 ! plant organ formation +relationship: regulates GO:1905393 ! plant organ formation +created_by: tb +creation_date: 2016-09-07T18:57:47Z + +[Term] +id: GO:1905429 +name: response to glycine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18984164] +synonym: "response to aminoacetic acid" EXACT [] +synonym: "response to aminoethanoic acid" EXACT [] +synonym: "response to Gly" EXACT [] +synonym: "response to glycin" EXACT [] +is_a: GO:0007584 ! response to nutrient +is_a: GO:0042493 ! response to drug +is_a: GO:0043200 ! response to amino acid +created_by: sl +creation_date: 2016-09-08T22:09:15Z + +[Term] +id: GO:1905430 +name: cellular response to glycine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18984164] +synonym: "cellular response to aminoacetic acid" EXACT [] +synonym: "cellular response to aminoethanoic acid" EXACT [] +synonym: "cellular response to Gly" EXACT [] +synonym: "cellular response to glycin" EXACT [] +is_a: GO:0031670 ! cellular response to nutrient +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071230 ! cellular response to amino acid stimulus +is_a: GO:1905429 ! response to glycine +created_by: sl +creation_date: 2016-09-08T22:09:23Z + +[Term] +id: GO:1905431 +name: microcystin transport +namespace: biological_process +def: "The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GO_REF:0000065, GOC:TermGenie, PMID:26055554] +is_a: GO:0015833 ! peptide transport +is_a: GO:1901998 ! toxin transport +created_by: cvs +creation_date: 2016-09-13T23:15:51Z + +[Term] +id: GO:1905432 +name: regulation of retrograde trans-synaptic signaling by neuropeptide +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] +synonym: "regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +is_a: GO:0099177 ! regulation of trans-synaptic signaling +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +relationship: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +created_by: bf +creation_date: 2016-09-14T10:56:47Z + +[Term] +id: GO:1905433 +name: negative regulation of retrograde trans-synaptic signaling by neuropeptide +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] +synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +synonym: "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +synonym: "inhibition of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] +synonym: "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +relationship: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +created_by: bf +creation_date: 2016-09-14T10:56:55Z + +[Term] +id: GO:1905434 +name: positive regulation of retrograde trans-synaptic signaling by neuropeptide +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] +synonym: "activation of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] +synonym: "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] +synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] +is_a: GO:0010647 ! positive regulation of cell communication +is_a: GO:0023056 ! positive regulation of signaling +is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +relationship: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide +created_by: bf +creation_date: 2016-09-14T10:57:02Z + +[Term] +id: GO:1905435 +name: regulation of histone H3-K4 trimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +is_a: GO:0051569 ! regulation of histone H3-K4 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080182 ! histone H3-K4 trimethylation +relationship: regulates GO:0080182 ! histone H3-K4 trimethylation +created_by: hbye +creation_date: 2016-09-14T13:08:55Z + +[Term] +id: GO:1905436 +name: negative regulation of histone H3-K4 trimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +synonym: "down regulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3-K4 trimethylation" NARROW [GOC:TermGenie] +is_a: GO:0051572 ! negative regulation of histone H3-K4 methylation +is_a: GO:1905435 ! regulation of histone H3-K4 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0080182 ! histone H3-K4 trimethylation +relationship: negatively_regulates GO:0080182 ! histone H3-K4 trimethylation +created_by: hbye +creation_date: 2016-09-14T13:09:03Z + +[Term] +id: GO:1905437 +name: positive regulation of histone H3-K4 trimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +synonym: "activation of histone H3-K4 trimethylation" NARROW [GOC:TermGenie] +synonym: "up regulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K4 trimethylation" EXACT [GOC:TermGenie] +is_a: GO:0051571 ! positive regulation of histone H3-K4 methylation +is_a: GO:1905435 ! regulation of histone H3-K4 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0080182 ! histone H3-K4 trimethylation +relationship: positively_regulates GO:0080182 ! histone H3-K4 trimethylation +created_by: hbye +creation_date: 2016-09-14T13:09:11Z + +[Term] +id: GO:1905438 +name: non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +namespace: biological_process +def: "Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation." [GO_REF:0000060, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25640183] +synonym: "beta-catenin-independent Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "beta-catenin-independent Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "beta-catenin-independent Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signalling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signalling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt-activated signaling pathway involved in mDA neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation" EXACT [GOC:TermGenie] +synonym: "non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production" EXACT [GOC:TermGenie] +is_a: GO:0035567 ! non-canonical Wnt signaling pathway +is_a: GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation +intersection_of: GO:0035567 ! non-canonical Wnt signaling pathway +intersection_of: part_of GO:1904948 ! midbrain dopaminergic neuron differentiation +created_by: bc +creation_date: 2016-09-14T15:52:22Z + +[Term] +id: GO:1905439 +name: response to chondroitin 6'-sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365850] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: cvs +creation_date: 2016-09-14T18:56:12Z + +[Term] +id: GO:1905440 +name: cellular response to chondroitin 6'-sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365850] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905439 ! response to chondroitin 6'-sulfate +created_by: cvs +creation_date: 2016-09-14T18:56:19Z + +[Term] +id: GO:1905441 +name: response to chondroitin 4'-sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365850] +is_a: GO:0001101 ! response to acid chemical +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: cvs +creation_date: 2016-09-14T18:56:27Z + +[Term] +id: GO:1905442 +name: cellular response to chondroitin 4'-sulfate +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22365850] +is_a: GO:0071229 ! cellular response to acid chemical +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905441 ! response to chondroitin 4'-sulfate +created_by: cvs +creation_date: 2016-09-14T18:56:34Z + +[Term] +id: GO:1905443 +name: regulation of clathrin coat assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of clathrin coat assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:15533940] +synonym: "regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048268 ! clathrin coat assembly +relationship: regulates GO:0048268 ! clathrin coat assembly +created_by: bf +creation_date: 2016-09-15T14:38:22Z + +[Term] +id: GO:1905444 +name: negative regulation of clathrin coat assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "down regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of clathrin coat assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin coat assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin coat assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of clathrin cage assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of clathrin coat assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1905443 ! regulation of clathrin coat assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048268 ! clathrin coat assembly +relationship: negatively_regulates GO:0048268 ! clathrin coat assembly +created_by: bf +creation_date: 2016-09-15T14:38:30Z + +[Term] +id: GO:1905445 +name: positive regulation of clathrin coat assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of clathrin coat assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:15533940] +synonym: "activation of clathrin cage assembly" NARROW [GOC:TermGenie] +synonym: "activation of clathrin coat assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of clathrin coat assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of clathrin coat assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of clathrin cage assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of clathrin coat assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1905443 ! regulation of clathrin coat assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048268 ! clathrin coat assembly +relationship: positively_regulates GO:0048268 ! clathrin coat assembly +created_by: bf +creation_date: 2016-09-15T14:38:38Z + +[Term] +id: GO:1905446 +name: regulation of mitochondrial ATP synthesis coupled electron transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23707074] +synonym: "regulation of mitochondrial electron transport" BROAD [GOC:TermGenie] +synonym: "regulation of organelle ATP synthesis coupled electron transport" BROAD [GOC:TermGenie] +is_a: GO:0002082 ! regulation of oxidative phosphorylation +is_a: GO:0043457 ! regulation of cellular respiration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +relationship: regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +created_by: dph +creation_date: 2016-09-15T18:57:58Z + +[Term] +id: GO:1905447 +name: negative regulation of mitochondrial ATP synthesis coupled electron transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23707074] +synonym: "down regulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial ATP synthesis coupled electron transport" NARROW [GOC:TermGenie] +is_a: GO:0090324 ! negative regulation of oxidative phosphorylation +is_a: GO:1901856 ! negative regulation of cellular respiration +is_a: GO:1905446 ! regulation of mitochondrial ATP synthesis coupled electron transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +relationship: negatively_regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +created_by: dph +creation_date: 2016-09-15T18:58:06Z + +[Term] +id: GO:1905448 +name: positive regulation of mitochondrial ATP synthesis coupled electron transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23707074] +synonym: "activation of mitochondrial ATP synthesis coupled electron transport" NARROW [GOC:TermGenie] +synonym: "up regulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial ATP synthesis coupled electron transport" EXACT [GOC:TermGenie] +is_a: GO:1901857 ! positive regulation of cellular respiration +is_a: GO:1903862 ! positive regulation of oxidative phosphorylation +is_a: GO:1905446 ! regulation of mitochondrial ATP synthesis coupled electron transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +relationship: positively_regulates GO:0042775 ! mitochondrial ATP synthesis coupled electron transport +created_by: dph +creation_date: 2016-09-15T18:58:14Z + +[Term] +id: GO:1905449 +name: regulation of Fc-gamma receptor signaling pathway involved in phagocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis." [GO_REF:0000058, GOC:TermGenie, PMID:18832707] +synonym: "regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0050764 ! regulation of phagocytosis +is_a: GO:0060368 ! regulation of Fc receptor mediated stimulatory signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +relationship: regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +created_by: sl +creation_date: 2016-09-15T19:41:50Z + +[Term] +id: GO:1905450 +name: negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis." [GO_REF:0000058, GOC:TermGenie, PMID:18832707] +synonym: "down regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "down regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "down-regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "downregulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "inhibition of Fc gamma receptor-dependent phagocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of Fcgamma receptor-mediated phagocytosis" NARROW [GOC:TermGenie] +synonym: "inhibition of IgG-mediated phagocytosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "negative regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0050765 ! negative regulation of phagocytosis +is_a: GO:1905449 ! regulation of Fc-gamma receptor signaling pathway involved in phagocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +relationship: negatively_regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +created_by: sl +creation_date: 2016-09-15T19:41:58Z + +[Term] +id: GO:1905451 +name: positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis." [GO_REF:0000058, GOC:TermGenie, PMID:18832707] +synonym: "activation of Fc gamma receptor-dependent phagocytosis" NARROW [GOC:TermGenie] +synonym: "activation of Fc-gamma receptor signaling pathway involved in phagocytosis" NARROW [GOC:TermGenie] +synonym: "activation of Fc-gamma receptor signalling pathway involved in phagocytosis" NARROW [GOC:TermGenie] +synonym: "activation of Fcgamma receptor-mediated phagocytosis" NARROW [GOC:TermGenie] +synonym: "activation of IgG-mediated phagocytosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "positive regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "up regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "up-regulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of Fc gamma receptor-dependent phagocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of Fcgamma receptor-mediated phagocytosis" EXACT [GOC:TermGenie] +synonym: "upregulation of IgG-mediated phagocytosis" EXACT [GOC:TermGenie] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0050766 ! positive regulation of phagocytosis +is_a: GO:0060369 ! positive regulation of Fc receptor mediated stimulatory signaling pathway +is_a: GO:1905449 ! regulation of Fc-gamma receptor signaling pathway involved in phagocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +relationship: positively_regulates GO:0038096 ! Fc-gamma receptor signaling pathway involved in phagocytosis +created_by: sl +creation_date: 2016-09-15T19:42:06Z + +[Term] +id: GO:1905452 +name: obsolete canonical Wnt signaling pathway involved in regulation of stem cell proliferation +namespace: biological_process +def: "OBSOLETE. Any canonical Wnt signaling pathway that is involved in regulation of stem cell proliferation." [GO_REF:0000060, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25640183] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "canonical Wnt receptor signaling pathway involved in regulation of stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in regulation of stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in regulation of stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in regulation of stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in regulation of stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in regulation of stem cell proliferation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: bc +creation_date: 2016-09-16T11:52:42Z + +[Term] +id: GO:1905453 +name: regulation of myeloid progenitor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002318 ! myeloid progenitor cell differentiation +relationship: regulates GO:0002318 ! myeloid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:18Z + +[Term] +id: GO:1905454 +name: negative regulation of myeloid progenitor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation +is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation +relationship: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:26Z + +[Term] +id: GO:1905455 +name: positive regulation of myeloid progenitor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +synonym: "activation of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation +is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation +relationship: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:33Z + +[Term] +id: GO:1905456 +name: regulation of lymphoid progenitor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002320 ! lymphoid progenitor cell differentiation +relationship: regulates GO:0002320 ! lymphoid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:40Z + +[Term] +id: GO:1905457 +name: negative regulation of lymphoid progenitor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] +is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation +is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation +relationship: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:48Z + +[Term] +id: GO:1905458 +name: positive regulation of lymphoid progenitor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] +synonym: "activation of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] +synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation +is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation +relationship: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation +created_by: rz +creation_date: 2016-09-16T12:32:55Z + +[Term] +id: GO:1905459 +name: regulation of vascular associated smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] +synonym: "regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +relationship: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +created_by: rph +creation_date: 2016-09-19T11:33:54Z + +[Term] +id: GO:1905460 +name: negative regulation of vascular associated smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] +synonym: "down regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of VSMC apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process +is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +relationship: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +created_by: rph +creation_date: 2016-09-19T11:34:03Z + +[Term] +id: GO:1905461 +name: positive regulation of vascular associated smooth muscle cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] +synonym: "activation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of VSMC apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of VSMC apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process +is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +relationship: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process +created_by: rph +creation_date: 2016-09-19T11:34:10Z + +[Term] +id: GO:1905462 +name: regulation of DNA duplex unwinding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA duplex unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +synonym: "regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "regulation of duplex DNA melting" EXACT [GOC:TermGenie] +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032508 ! DNA duplex unwinding +relationship: regulates GO:0032508 ! DNA duplex unwinding +created_by: ans +creation_date: 2016-09-19T11:58:41Z + +[Term] +id: GO:1905463 +name: negative regulation of DNA duplex unwinding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +synonym: "down regulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "down regulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "downregulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA duplex unwinding" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA unwinding" NARROW [GOC:TermGenie] +synonym: "inhibition of duplex DNA melting" NARROW [GOC:TermGenie] +synonym: "negative regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "negative regulation of duplex DNA melting" EXACT [GOC:TermGenie] +is_a: GO:1905462 ! regulation of DNA duplex unwinding +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032508 ! DNA duplex unwinding +relationship: negatively_regulates GO:0032508 ! DNA duplex unwinding +created_by: ans +creation_date: 2016-09-19T11:58:48Z + +[Term] +id: GO:1905464 +name: positive regulation of DNA duplex unwinding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +synonym: "activation of DNA duplex unwinding" NARROW [GOC:TermGenie] +synonym: "activation of DNA unwinding" NARROW [GOC:TermGenie] +synonym: "activation of duplex DNA melting" NARROW [GOC:TermGenie] +synonym: "positive regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "positive regulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "up regulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of duplex DNA melting" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA duplex unwinding" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA unwinding" EXACT [GOC:TermGenie] +synonym: "upregulation of duplex DNA melting" EXACT [GOC:TermGenie] +is_a: GO:1905462 ! regulation of DNA duplex unwinding +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032508 ! DNA duplex unwinding +relationship: positively_regulates GO:0032508 ! DNA duplex unwinding +created_by: ans +creation_date: 2016-09-19T11:58:55Z + +[Term] +id: GO:1905465 +name: regulation of G-quadruplex DNA unwinding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044806 ! G-quadruplex DNA unwinding +relationship: regulates GO:0044806 ! G-quadruplex DNA unwinding +created_by: ans +creation_date: 2016-09-19T12:15:45Z + +[Term] +id: GO:1905466 +name: negative regulation of G-quadruplex DNA unwinding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +synonym: "down regulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +synonym: "downregulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +synonym: "inhibition of G-quadruplex DNA unwinding" NARROW [GOC:TermGenie] +is_a: GO:1905465 ! regulation of G-quadruplex DNA unwinding +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044806 ! G-quadruplex DNA unwinding +relationship: negatively_regulates GO:0044806 ! G-quadruplex DNA unwinding +created_by: ans +creation_date: 2016-09-19T12:15:53Z + +[Term] +id: GO:1905467 +name: positive regulation of G-quadruplex DNA unwinding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding." [GO_REF:0000058, GOC:TermGenie, PMID:26503245] +synonym: "activation of G-quadruplex DNA unwinding" NARROW [GOC:TermGenie] +synonym: "up regulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +synonym: "upregulation of G-quadruplex DNA unwinding" EXACT [GOC:TermGenie] +is_a: GO:1905465 ! regulation of G-quadruplex DNA unwinding +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044806 ! G-quadruplex DNA unwinding +relationship: positively_regulates GO:0044806 ! G-quadruplex DNA unwinding +created_by: ans +creation_date: 2016-09-19T12:16:01Z + +[Term] +id: GO:1905468 +name: regulation of clathrin-coated pit assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "regulation of coated pit formation" EXACT [GOC:TermGenie] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905224 ! clathrin-coated pit assembly +relationship: regulates GO:1905224 ! clathrin-coated pit assembly +created_by: bf +creation_date: 2016-09-20T10:04:37Z + +[Term] +id: GO:1905469 +name: negative regulation of clathrin-coated pit assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353] +synonym: "down regulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "down regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "downregulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "inhibition of clathrin-coated pit assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of clathrin-coated pit formation" NARROW [GOC:TermGenie] +synonym: "inhibition of coated pit assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of coated pit formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of coated pit formation" EXACT [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1905468 ! regulation of clathrin-coated pit assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905224 ! clathrin-coated pit assembly +relationship: negatively_regulates GO:1905224 ! clathrin-coated pit assembly +created_by: bf +creation_date: 2016-09-20T10:04:45Z + +[Term] +id: GO:1905470 +name: positive regulation of clathrin-coated pit assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] +synonym: "activation of clathrin-coated pit assembly" NARROW [GOC:TermGenie] +synonym: "activation of clathrin-coated pit formation" NARROW [GOC:TermGenie] +synonym: "activation of coated pit assembly" NARROW [GOC:TermGenie] +synonym: "activation of coated pit formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "up regulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "up regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of coated pit formation" EXACT [GOC:TermGenie] +synonym: "upregulation of clathrin-coated pit assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of clathrin-coated pit formation" EXACT [GOC:TermGenie] +synonym: "upregulation of coated pit assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of coated pit formation" EXACT [GOC:TermGenie] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1905468 ! regulation of clathrin-coated pit assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905224 ! clathrin-coated pit assembly +relationship: positively_regulates GO:1905224 ! clathrin-coated pit assembly +created_by: bf +creation_date: 2016-09-20T10:04:53Z + +[Term] +id: GO:1905471 +name: regulation of histone H3-K79 dimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +synonym: "regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:2001160 ! regulation of histone H3-K79 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097725 ! histone H3-K79 dimethylation +relationship: regulates GO:0097725 ! histone H3-K79 dimethylation +created_by: hbye +creation_date: 2016-09-21T15:27:02Z + +[Term] +id: GO:1905472 +name: negative regulation of histone H3-K79 dimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +synonym: "down regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "down regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "downregulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "inhibition of histone H3 K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone H3-K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "inhibition of histone lysine H3 K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:1905471 ! regulation of histone H3-K79 dimethylation +is_a: GO:2001161 ! negative regulation of histone H3-K79 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097725 ! histone H3-K79 dimethylation +relationship: negatively_regulates GO:0097725 ! histone H3-K79 dimethylation +created_by: hbye +creation_date: 2016-09-21T15:27:10Z + +[Term] +id: GO:1905473 +name: positive regulation of histone H3-K79 dimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation." [GO_REF:0000058, GOC:TermGenie, PMID:27541139] +synonym: "activation of histone H3 K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "activation of histone H3-K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "activation of histone lysine H3 K79 dimethylation" NARROW [GOC:TermGenie] +synonym: "positive regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "positive regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3 K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone H3-K79 dimethylation" EXACT [GOC:TermGenie] +synonym: "upregulation of histone lysine H3 K79 dimethylation" EXACT [GOC:TermGenie] +is_a: GO:1905471 ! regulation of histone H3-K79 dimethylation +is_a: GO:2001162 ! positive regulation of histone H3-K79 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097725 ! histone H3-K79 dimethylation +relationship: positively_regulates GO:0097725 ! histone H3-K79 dimethylation +created_by: hbye +creation_date: 2016-09-21T15:27:17Z + +[Term] +id: GO:1905474 +name: canonical Wnt signaling pathway involved in stem cell proliferation +namespace: biological_process +def: "Any canonical Wnt signaling pathway that is involved in stem cell proliferation." [GO_REF:0000060, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25640183] +synonym: "canonical Wnt receptor signaling pathway involved in stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "canonical Wnt-activated signaling pathway involved in stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "frizzled-1 receptor signaling pathway involved in stem cell proliferation" NARROW [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway through beta-catenin involved in stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signaling pathway via beta-catenin involved in stem cell proliferation" EXACT [GOC:TermGenie] +synonym: "Wnt receptor signalling pathway through beta-catenin involved in stem cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0044340 ! canonical Wnt signaling pathway involved in regulation of cell proliferation +intersection_of: GO:0060070 ! canonical Wnt signaling pathway +intersection_of: part_of GO:0072089 ! stem cell proliferation +relationship: part_of GO:0072089 ! stem cell proliferation +created_by: bc +creation_date: 2016-09-21T15:59:53Z + +[Term] +id: GO:1905475 +name: regulation of protein localization to membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072657 ! protein localization to membrane +relationship: regulates GO:0072657 ! protein localization to membrane +created_by: bc +creation_date: 2016-09-21T16:20:03Z + +[Term] +id: GO:1905476 +name: negative regulation of protein localization to membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in membrane" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to membrane" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072657 ! protein localization to membrane +relationship: negatively_regulates GO:0072657 ! protein localization to membrane +created_by: bc +creation_date: 2016-09-21T16:20:10Z + +[Term] +id: GO:1905477 +name: positive regulation of protein localization to membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] +synonym: "activation of protein localisation in membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in membrane" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to membrane" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905475 ! regulation of protein localization to membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072657 ! protein localization to membrane +relationship: positively_regulates GO:0072657 ! protein localization to membrane +created_by: bc +creation_date: 2016-09-21T16:20:18Z + +[Term] +id: GO:1905478 +name: regulation of glutamate-ammonia ligase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10377385] +synonym: "regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004356 ! glutamate-ammonia ligase activity +relationship: regulates GO:0004356 ! glutamate-ammonia ligase activity +created_by: pga +creation_date: 2016-09-22T09:58:34Z + +[Term] +id: GO:1905479 +name: negative regulation of glutamate-ammonia ligase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10377385] +synonym: "down regulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "down regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "downregulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of glutamate-ammonia ligase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glutamine synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of glutamylhydroxamic synthetase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of L-glutamate:ammonia ligase (ADP-forming)" NARROW [GOC:TermGenie] +synonym: "inhibition of L-glutamine synthetase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "negative regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:0051352 ! negative regulation of ligase activity +is_a: GO:1905478 ! regulation of glutamate-ammonia ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004356 ! glutamate-ammonia ligase activity +relationship: negatively_regulates GO:0004356 ! glutamate-ammonia ligase activity +created_by: pga +creation_date: 2016-09-22T09:58:42Z + +[Term] +id: GO:1905480 +name: positive regulation of glutamate-ammonia ligase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10377385] +synonym: "activation of glutamate-ammonia ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of glutamine synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of glutamylhydroxamic synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-glutamate:ammonia ligase (ADP-forming)" NARROW [GOC:TermGenie] +synonym: "activation of L-glutamine synthetase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamate-ammonia ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamine synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of glutamylhydroxamic synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-glutamate:ammonia ligase (ADP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of L-glutamine synthetase activity" EXACT [GOC:TermGenie] +is_a: GO:0051351 ! positive regulation of ligase activity +is_a: GO:1905478 ! regulation of glutamate-ammonia ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004356 ! glutamate-ammonia ligase activity +relationship: positively_regulates GO:0004356 ! glutamate-ammonia ligase activity +created_by: pga +creation_date: 2016-09-22T09:58:50Z + +[Term] +id: GO:1905481 +name: obsolete cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint +namespace: biological_process +def: "OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint." [GO_REF:0000060, GOC:TermGenie, PMID:10523629] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: vw +creation_date: 2016-09-22T18:20:35Z + +[Term] +id: GO:1905482 +name: obsolete cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint +namespace: biological_process +def: "OBSOLETE. Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint." [GO_REF:0000060, GOC:TermGenie, PMID:10523629] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: vw +creation_date: 2016-09-22T18:23:55Z + +[Term] +id: GO:1905483 +name: regulation of motor neuron migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +is_a: GO:2001222 ! regulation of neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097475 ! motor neuron migration +relationship: regulates GO:0097475 ! motor neuron migration +created_by: hbye +creation_date: 2016-09-23T12:49:54Z + +[Term] +id: GO:1905484 +name: negative regulation of motor neuron migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie] +synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie] +synonym: "inhibition of motor neuron migration" NARROW [GOC:TermGenie] +is_a: GO:1905483 ! regulation of motor neuron migration +is_a: GO:2001223 ! negative regulation of neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097475 ! motor neuron migration +relationship: negatively_regulates GO:0097475 ! motor neuron migration +created_by: hbye +creation_date: 2016-09-23T12:50:11Z + +[Term] +id: GO:1905485 +name: positive regulation of motor neuron migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "activation of motor neuron migration" NARROW [GOC:TermGenie] +synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie] +synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie] +is_a: GO:1905483 ! regulation of motor neuron migration +is_a: GO:2001224 ! positive regulation of neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097475 ! motor neuron migration +relationship: positively_regulates GO:0097475 ! motor neuron migration +created_by: hbye +creation_date: 2016-09-23T12:50:19Z + +[Term] +id: GO:1905486 +name: regulation of anterior/posterior axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033564 ! anterior/posterior axon guidance +relationship: regulates GO:0033564 ! anterior/posterior axon guidance +created_by: hbye +creation_date: 2016-09-23T13:18:33Z + +[Term] +id: GO:1905487 +name: negative regulation of anterior/posterior axon guidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "down regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "downregulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "inhibition of anterior-posterior axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of anterior/posterior axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of anterior/posterior axon pathfinding" NARROW [GOC:TermGenie] +synonym: "negative regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "negative regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902668 ! negative regulation of axon guidance +is_a: GO:1905486 ! regulation of anterior/posterior axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033564 ! anterior/posterior axon guidance +relationship: negatively_regulates GO:0033564 ! anterior/posterior axon guidance +created_by: hbye +creation_date: 2016-09-23T13:18:41Z + +[Term] +id: GO:1905488 +name: positive regulation of anterior/posterior axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "activation of anterior-posterior axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of anterior/posterior axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of anterior/posterior axon pathfinding" NARROW [GOC:TermGenie] +synonym: "positive regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "positive regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +synonym: "upregulation of anterior-posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of anterior/posterior axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of anterior/posterior axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902669 ! positive regulation of axon guidance +is_a: GO:1905486 ! regulation of anterior/posterior axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033564 ! anterior/posterior axon guidance +relationship: positively_regulates GO:0033564 ! anterior/posterior axon guidance +created_by: hbye +creation_date: 2016-09-23T13:18:48Z + +[Term] +id: GO:1905489 +name: regulation of sensory neuron axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sensory neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097374 ! sensory neuron axon guidance +relationship: regulates GO:0097374 ! sensory neuron axon guidance +created_by: hbye +creation_date: 2016-09-23T13:18:56Z + +[Term] +id: GO:1905490 +name: negative regulation of sensory neuron axon guidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "down regulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "inhibition of sensory neuron axon guidance" NARROW [GOC:TermGenie] +is_a: GO:1902668 ! negative regulation of axon guidance +is_a: GO:1905489 ! regulation of sensory neuron axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097374 ! sensory neuron axon guidance +relationship: negatively_regulates GO:0097374 ! sensory neuron axon guidance +created_by: hbye +creation_date: 2016-09-23T13:19:04Z + +[Term] +id: GO:1905491 +name: positive regulation of sensory neuron axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "activation of sensory neuron axon guidance" NARROW [GOC:TermGenie] +synonym: "up regulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of sensory neuron axon guidance" EXACT [GOC:TermGenie] +is_a: GO:1902669 ! positive regulation of axon guidance +is_a: GO:1905489 ! regulation of sensory neuron axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097374 ! sensory neuron axon guidance +relationship: positively_regulates GO:0097374 ! sensory neuron axon guidance +created_by: hbye +creation_date: 2016-09-23T13:19:12Z + +[Term] +id: GO:1905492 +name: positive regulation of branching morphogenesis of a nerve +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] +synonym: "activation of branching morphogenesis of a nerve" NARROW [GOC:TermGenie] +synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] +synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] +synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048755 ! branching morphogenesis of a nerve +relationship: positively_regulates GO:0048755 ! branching morphogenesis of a nerve +created_by: hbye +creation_date: 2016-09-23T14:11:52Z + +[Term] +id: GO:1905493 +name: regulation of G-quadruplex DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +synonym: "regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "regulation of G quartet binding" BROAD [GOC:TermGenie] +synonym: "regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "regulation of G-quartet binding" BROAD [GOC:TermGenie] +synonym: "regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051880 ! G-quadruplex DNA binding +relationship: regulates GO:0051880 ! G-quadruplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:53:21Z + +[Term] +id: GO:1905494 +name: negative regulation of G-quadruplex DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +synonym: "down regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of G quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of G quartet DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of G-DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of G-quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of G-quartet DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "inhibition of tetraplex DNA binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:1905493 ! regulation of G-quadruplex DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051880 ! G-quadruplex DNA binding +relationship: negatively_regulates GO:0051880 ! G-quadruplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:53:29Z + +[Term] +id: GO:1905495 +name: positive regulation of G-quadruplex DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +synonym: "activation of G quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of G quartet DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of G-DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of G-quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of G-quartet DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of quadruplex DNA binding" NARROW [GOC:TermGenie] +synonym: "activation of tetraplex DNA binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of G quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of G quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of G-DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of G-quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of G-quartet DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of quadruplex DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of tetraplex DNA binding" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:1905493 ! regulation of G-quadruplex DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051880 ! G-quadruplex DNA binding +relationship: positively_regulates GO:0051880 ! G-quadruplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:53:37Z + +[Term] +id: GO:1905496 +name: regulation of triplex DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of triplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045142 ! triplex DNA binding +relationship: regulates GO:0045142 ! triplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:57:09Z + +[Term] +id: GO:1905497 +name: negative regulation of triplex DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +synonym: "down regulation of triplex DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of triplex DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of triplex DNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of triplex DNA binding" NARROW [GOC:TermGenie] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:1905496 ! regulation of triplex DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045142 ! triplex DNA binding +relationship: negatively_regulates GO:0045142 ! triplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:57:17Z + +[Term] +id: GO:1905498 +name: positive regulation of triplex DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of triplex DNA binding." [GO_REF:0000059, GOC:TermGenie, PMID:26503245] +synonym: "activation of triplex DNA binding" NARROW [GOC:TermGenie] +synonym: "up regulation of triplex DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of triplex DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of triplex DNA binding" EXACT [GOC:TermGenie] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:1905496 ! regulation of triplex DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045142 ! triplex DNA binding +relationship: positively_regulates GO:0045142 ! triplex DNA binding +created_by: ans +creation_date: 2016-09-26T14:57:25Z + +[Term] +id: GO:1905499 +name: trichome papilla formation +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a trichome papilla." [GO_REF:0000079, GOC:tb, GOC:TermGenie, PMID:24014871] +synonym: "trichome papilla assembly" RELATED [] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0030031 ! cell projection assembly +relationship: part_of GO:0010090 ! trichome morphogenesis +created_by: tb +creation_date: 2016-09-27T00:28:06Z + +[Term] +id: GO:1905500 +name: obsolete heteroreceptor complex assembly +namespace: biological_process +def: "OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a heteroreceptor complex." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24157794] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "heteroreceptor complex formation" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: pad +creation_date: 2016-09-27T10:49:56Z + +[Term] +id: GO:1905501 +name: obsolete heteroreceptor complex disassembly +namespace: biological_process +def: "OBSOLETE. The disaggregation of a heteroreceptor complex into its constituent components." [GO_REF:0000079, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24157794] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: pad +creation_date: 2016-09-27T10:50:04Z + +[Term] +id: GO:1905502 +name: acetyl-CoA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with acetyl-CoA." [GO_REF:0000067, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:24927529] +is_a: GO:0032559 ! adenyl ribonucleotide binding +is_a: GO:0033218 ! amide binding +is_a: GO:0043168 ! anion binding +is_a: GO:0050662 ! coenzyme binding +is_a: GO:1901681 ! sulfur compound binding +created_by: bc +creation_date: 2016-09-27T16:33:44Z + +[Term] +id: GO:1905503 +name: regulation of motile cilium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] +synonym: "regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "regulation of motile primary cilium assembly" RELATED [] +synonym: "regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "regulation of nodal cilium formation" RELATED [GOC:TermGenie] +is_a: GO:1902017 ! regulation of cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044458 ! motile cilium assembly +relationship: regulates GO:0044458 ! motile cilium assembly +created_by: krc +creation_date: 2016-09-27T18:27:47Z + +[Term] +id: GO:1905504 +name: negative regulation of motile cilium assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] +synonym: "down regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "down regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "down regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "downregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "downregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "downregulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "inhibition of motile primary cilia assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of motile primary cilia formation" NARROW [GOC:TermGenie] +synonym: "inhibition of motile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of motile primary cilium formation" NARROW [GOC:TermGenie] +synonym: "inhibition of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of motile primary cilium assembly" RELATED [] +synonym: "negative regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of nodal cilium formation" RELATED [GOC:TermGenie] +is_a: GO:1902018 ! negative regulation of cilium assembly +is_a: GO:1905503 ! regulation of motile cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044458 ! motile cilium assembly +relationship: negatively_regulates GO:0044458 ! motile cilium assembly +created_by: krc +creation_date: 2016-09-27T18:27:55Z + +[Term] +id: GO:1905505 +name: positive regulation of motile cilium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] +synonym: "activation of motile primary cilia assembly" NARROW [GOC:TermGenie] +synonym: "activation of motile primary cilia formation" NARROW [GOC:TermGenie] +synonym: "activation of motile primary cilium assembly" NARROW [GOC:TermGenie] +synonym: "activation of motile primary cilium formation" NARROW [GOC:TermGenie] +synonym: "activation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "activation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of motile primary cilium assembly" RELATED [] +synonym: "positive regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "up regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "up regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "up regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of nodal cilium formation" RELATED [GOC:TermGenie] +synonym: "upregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of motile primary cilia formation" RELATED [GOC:TermGenie] +synonym: "upregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of motile primary cilium formation" RELATED [GOC:TermGenie] +synonym: "upregulation of nodal cilium assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of nodal cilium formation" RELATED [GOC:TermGenie] +is_a: GO:0045724 ! positive regulation of cilium assembly +is_a: GO:1905503 ! regulation of motile cilium assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044458 ! motile cilium assembly +relationship: positively_regulates GO:0044458 ! motile cilium assembly +created_by: krc +creation_date: 2016-09-27T18:28:03Z + +[Term] +id: GO:1905506 +name: gerontoplast stroma +namespace: cellular_component +def: "Any plastid stroma that is part of a gerontoplast." [GO_REF:0000064, GOC:mag, GOC:TermGenie, PMID:11212360] +is_a: GO:0009532 ! plastid stroma +intersection_of: GO:0009532 ! plastid stroma +intersection_of: part_of GO:0034400 ! gerontoplast +relationship: part_of GO:0034400 ! gerontoplast +created_by: tb +creation_date: 2016-09-27T20:01:34Z + +[Term] +id: GO:1905507 +name: obsolete cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint +namespace: biological_process +def: "OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint." [GO_REF:0000060, GOC:TermGenie, PMID:10523629] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: vw +creation_date: 2016-09-28T12:20:28Z + +[Term] +id: GO:1905508 +name: protein localization to microtubule organizing center +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center." [GO_REF:0000087, GOC:TermGenie, PMID:19001497] +synonym: "protein localisation in microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localisation to microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localization in microtubule organizing center" EXACT [GOC:TermGenie] +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +created_by: mah +creation_date: 2016-09-28T12:32:16Z + +[Term] +id: GO:1905509 +name: protein localization to interphase microtubule organizing center +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center." [GO_REF:0000087, GOC:TermGenie, PMID:19001497] +synonym: "protein localisation in interphase microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localisation to interphase microtubule organizing center" EXACT [GOC:TermGenie] +synonym: "protein localization in interphase microtubule organizing center" EXACT [GOC:TermGenie] +is_a: GO:1905508 ! protein localization to microtubule organizing center +created_by: mah +creation_date: 2016-09-28T12:32:24Z + +[Term] +id: GO:1905510 +name: negative regulation of myosin II filament assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27237792, PMID:7691416] +comment: positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules +synonym: "down regulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "down-regulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "downregulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "inhibition of myosin II filament assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "negative regulation of myosin II polymerization" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0043520 ! regulation of myosin II filament assembly +is_a: GO:1904900 ! negative regulation of myosin II filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031036 ! myosin II filament assembly +relationship: negatively_regulates GO:0031036 ! myosin II filament assembly +created_by: pf +creation_date: 2016-09-28T13:47:56Z + +[Term] +id: GO:1905511 +name: positive regulation of myosin II filament assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myosin II filament assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27237792, PMID:7691416] +comment: positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules +synonym: "activation of myosin II filament assembly" NARROW [GOC:TermGenie] +synonym: "activation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "positive regulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "up regulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "up-regulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of myosin II polymerization" RELATED [GOC:TermGenie] +synonym: "upregulation of myosin II filament assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of myosin II polymerization" RELATED [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0043520 ! regulation of myosin II filament assembly +is_a: GO:1904901 ! positive regulation of myosin II filament organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031036 ! myosin II filament assembly +relationship: positively_regulates GO:0031036 ! myosin II filament assembly +created_by: pf +creation_date: 2016-09-28T13:48:03Z + +[Term] +id: GO:1905512 +name: regulation of short-term synaptic potentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of short-term synaptic potentiation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:15470145] +synonym: "regulation of synaptic facilitation" EXACT [GOC:TermGenie] +is_a: GO:0048167 ! regulation of synaptic plasticity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990926 ! short-term synaptic potentiation +relationship: regulates GO:1990926 ! short-term synaptic potentiation +created_by: hjd +creation_date: 2016-09-28T17:40:15Z + +[Term] +id: GO:1905513 +name: negative regulation of short-term synaptic potentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:15470145] +synonym: "down regulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "down-regulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "downregulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "inhibition of short-term synaptic potentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of synaptic facilitation" NARROW [GOC:TermGenie] +synonym: "negative regulation of synaptic facilitation" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1905512 ! regulation of short-term synaptic potentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990926 ! short-term synaptic potentiation +relationship: negatively_regulates GO:1990926 ! short-term synaptic potentiation +created_by: hjd +creation_date: 2016-09-28T17:40:23Z + +[Term] +id: GO:1905514 +name: positive regulation of short-term synaptic potentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation." [GO_REF:0000058, GOC:hjd, GOC:TermGenie, PMID:15470145] +synonym: "activation of short-term synaptic potentiation" NARROW [GOC:TermGenie] +synonym: "activation of synaptic facilitation" NARROW [GOC:TermGenie] +synonym: "positive regulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "up regulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "up-regulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of synaptic facilitation" EXACT [GOC:TermGenie] +synonym: "upregulation of short-term synaptic potentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of synaptic facilitation" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1905512 ! regulation of short-term synaptic potentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990926 ! short-term synaptic potentiation +relationship: positively_regulates GO:1990926 ! short-term synaptic potentiation +created_by: hjd +creation_date: 2016-09-28T17:40:30Z + +[Term] +id: GO:1905515 +name: non-motile cilium assembly +namespace: biological_process +alt_id: GO:0035058 +def: "The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium." [GO_REF:0000079, GOC:cilia, GOC:kmv, GOC:TermGenie, PMID:14521833, PMID:14521834] +synonym: "immotile primary cilium assembly" RELATED [GOC:bf] +synonym: "non-motile cilium formation" EXACT [GOC:TermGenie] +synonym: "nonmotile cilium assembly" EXACT [GOC:TermGenie] +synonym: "nonmotile cilium formation" EXACT [GOC:TermGenie] +synonym: "nonmotile primary cilia assembly" RELATED [GOC:bf] +synonym: "nonmotile primary cilium assembly" RELATED [] +synonym: "sensory cilium assembly" RELATED [GOC:kmv] +synonym: "sensory cilium biogenesis" RELATED [GOC:mah] +is_a: GO:0060271 ! cilium assembly +created_by: pr +creation_date: 2016-09-30T11:55:15Z + +[Term] +id: GO:1905516 +name: positive regulation of fertilization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576] +synonym: "activation of fertilization" NARROW [GOC:TermGenie] +synonym: "activation of syngamy" NARROW [GOC:TermGenie] +synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie] +synonym: "up regulation of fertilization" EXACT [GOC:TermGenie] +synonym: "up regulation of syngamy" EXACT [GOC:TermGenie] +synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie] +synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie] +synonym: "upregulation of fertilization" EXACT [GOC:TermGenie] +synonym: "upregulation of syngamy" EXACT [GOC:TermGenie] +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0080154 ! regulation of fertilization +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009566 ! fertilization +relationship: positively_regulates GO:0009566 ! fertilization +created_by: pr +creation_date: 2016-09-30T14:32:32Z + +[Term] +id: GO:1905517 +name: macrophage migration +namespace: biological_process +def: "The orderly movement of a macrophage from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:25749876] +is_a: GO:0097529 ! myeloid leukocyte migration +created_by: sl +creation_date: 2016-09-30T22:17:45Z + +[Term] +id: GO:1905518 +name: regulation of presynaptic active zone assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of presynaptic active zone assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15797875] +synonym: "regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +is_a: GO:1905606 ! regulation of presynapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904071 ! presynaptic active zone assembly +relationship: regulates GO:1904071 ! presynaptic active zone assembly +created_by: rl +creation_date: 2016-10-01T09:37:51Z + +[Term] +id: GO:1905519 +name: negative regulation of presynaptic active zone assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15797875] +synonym: "down regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "down regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "down regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "down regulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "down-regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "downregulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "downregulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "downregulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "inhibition of pre-synaptic active zone assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "inhibition of pre-synaptic active zone formation" NARROW [GOC:TermGenie] +synonym: "inhibition of presynaptic active zone assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of presynaptic active zone formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +is_a: GO:1905518 ! regulation of presynaptic active zone assembly +is_a: GO:1905607 ! negative regulation of presynapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904071 ! presynaptic active zone assembly +relationship: negatively_regulates GO:1904071 ! presynaptic active zone assembly +created_by: rl +creation_date: 2016-10-01T09:38:00Z + +[Term] +id: GO:1905520 +name: positive regulation of presynaptic active zone assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15797875] +synonym: "activation of pre-synaptic active zone assembly" NARROW [GOC:TermGenie] +synonym: "activation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "activation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "activation of pre-synaptic active zone formation" NARROW [GOC:TermGenie] +synonym: "activation of presynaptic active zone assembly" NARROW [GOC:TermGenie] +synonym: "activation of presynaptic active zone formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "up regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "up regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "up regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "up-regulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "upregulation of pre-synaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of pre-synaptic active zone component assembly" NARROW [GOC:TermGenie] +synonym: "upregulation of pre-synaptic active zone component formation" NARROW [GOC:TermGenie] +synonym: "upregulation of pre-synaptic active zone formation" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic active zone assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic active zone formation" EXACT [GOC:TermGenie] +is_a: GO:1905518 ! regulation of presynaptic active zone assembly +is_a: GO:1905608 ! positive regulation of presynapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904071 ! presynaptic active zone assembly +relationship: positively_regulates GO:1904071 ! presynaptic active zone assembly +created_by: rl +creation_date: 2016-10-01T09:38:07Z + +[Term] +id: GO:1905521 +name: regulation of macrophage migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage migration." [GO_REF:0000058, GOC:TermGenie, PMID:25749876] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905517 ! macrophage migration +relationship: regulates GO:1905517 ! macrophage migration +created_by: sl +creation_date: 2016-10-03T15:29:06Z + +[Term] +id: GO:1905522 +name: negative regulation of macrophage migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration." [GO_REF:0000058, GOC:TermGenie, PMID:25749876] +synonym: "down regulation of macrophage migration" EXACT [GOC:TermGenie] +synonym: "down-regulation of macrophage migration" EXACT [GOC:TermGenie] +synonym: "downregulation of macrophage migration" EXACT [GOC:TermGenie] +synonym: "inhibition of macrophage migration" NARROW [GOC:TermGenie] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:1905521 ! regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905517 ! macrophage migration +relationship: negatively_regulates GO:1905517 ! macrophage migration +created_by: sl +creation_date: 2016-10-03T15:29:14Z + +[Term] +id: GO:1905523 +name: positive regulation of macrophage migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage migration." [GO_REF:0000058, GOC:TermGenie, PMID:25749876] +synonym: "activation of macrophage migration" NARROW [GOC:TermGenie] +synonym: "up regulation of macrophage migration" EXACT [GOC:TermGenie] +synonym: "up-regulation of macrophage migration" EXACT [GOC:TermGenie] +synonym: "upregulation of macrophage migration" EXACT [GOC:TermGenie] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:1905521 ! regulation of macrophage migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905517 ! macrophage migration +relationship: positively_regulates GO:1905517 ! macrophage migration +created_by: sl +creation_date: 2016-10-03T15:29:21Z + +[Term] +id: GO:1905524 +name: negative regulation of protein autoubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:17237821] +synonym: "down regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "down regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein autoubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "downregulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "downregulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "inhibition of protein auto-ubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of protein auto-ubiquitinylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein autoubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of protein autoubiquitinylation" NARROW [GOC:TermGenie] +synonym: "inhibition of protein self-ubiquitination" NARROW [GOC:TermGenie] +synonym: "inhibition of protein self-ubiquitinylation" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein auto-ubiquitination" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein auto-ubiquitinylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein autoubiquitinylation" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein self-ubiquitination" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein self-ubiquitinylation" EXACT [GOC:TermGenie] +is_a: GO:0031397 ! negative regulation of protein ubiquitination +is_a: GO:1902498 ! regulation of protein autoubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051865 ! protein autoubiquitination +relationship: negatively_regulates GO:0051865 ! protein autoubiquitination +created_by: bc +creation_date: 2016-10-04T10:53:25Z + +[Term] +id: GO:1905525 +name: obsolete regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron +namespace: biological_process +def: "OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter in response to iron that results in regulation of ferrichrome biosynthetic process." [GO_REF:0000063, GOC:TermGenie, PMID:20435771] +comment: This term was made obsolete because it was added in error. +synonym: "regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-10-04T15:46:03Z + +[Term] +id: GO:1905526 +name: regulation of Golgi lumen acidification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Golgi lumen acidification." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23447592] +is_a: GO:0032847 ! regulation of cellular pH reduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061795 ! Golgi lumen acidification +relationship: regulates GO:0061795 ! Golgi lumen acidification +created_by: dph +creation_date: 2016-10-05T13:16:25Z + +[Term] +id: GO:1905527 +name: negative regulation of Golgi lumen acidification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23447592] +synonym: "down regulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +synonym: "down-regulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +synonym: "downregulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +synonym: "inhibition of Golgi lumen acidification" NARROW [GOC:TermGenie] +is_a: GO:0032848 ! negative regulation of cellular pH reduction +is_a: GO:1905526 ! regulation of Golgi lumen acidification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061795 ! Golgi lumen acidification +relationship: negatively_regulates GO:0061795 ! Golgi lumen acidification +created_by: dph +creation_date: 2016-10-05T13:16:33Z + +[Term] +id: GO:1905528 +name: positive regulation of Golgi lumen acidification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification." [GO_REF:0000058, GOC:dph, GOC:TermGenie, PMID:23447592] +synonym: "activation of Golgi lumen acidification" NARROW [GOC:TermGenie] +synonym: "up regulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +synonym: "up-regulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +synonym: "upregulation of Golgi lumen acidification" EXACT [GOC:TermGenie] +is_a: GO:0032849 ! positive regulation of cellular pH reduction +is_a: GO:1905526 ! regulation of Golgi lumen acidification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061795 ! Golgi lumen acidification +relationship: positively_regulates GO:0061795 ! Golgi lumen acidification +created_by: dph +creation_date: 2016-10-05T13:16:41Z + +[Term] +id: GO:1905529 +name: regulation of uracil import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of uracil import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:26536126] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098721 ! uracil import across plasma membrane +relationship: regulates GO:0098721 ! uracil import across plasma membrane +created_by: vw +creation_date: 2016-10-05T21:03:40Z + +[Term] +id: GO:1905530 +name: negative regulation of uracil import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:26536126] +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:1905529 ! regulation of uracil import across plasma membrane +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098721 ! uracil import across plasma membrane +relationship: negatively_regulates GO:0098721 ! uracil import across plasma membrane +created_by: vw +creation_date: 2016-10-05T21:03:48Z + +[Term] +id: GO:1905531 +name: positive regulation of uracil import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:26536126] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:1905529 ! regulation of uracil import across plasma membrane +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098721 ! uracil import across plasma membrane +relationship: positively_regulates GO:0098721 ! uracil import across plasma membrane +created_by: vw +creation_date: 2016-10-05T21:03:56Z + +[Term] +id: GO:1905532 +name: regulation of leucine import across plasma membrane +namespace: biological_process +alt_id: GO:1903128 +def: "Any process that modulates the frequency, rate or extent of leucine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:10467003] +synonym: "regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "regulation of leucine import into cell" EXACT [] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098713 ! leucine import across plasma membrane +relationship: regulates GO:0098713 ! leucine import across plasma membrane +created_by: vw +creation_date: 2014-06-25T13:09:51Z + +[Term] +id: GO:1905533 +name: negative regulation of leucine import across plasma membrane +namespace: biological_process +alt_id: GO:1903129 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:10467003] +synonym: "down regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "down regulation of leucine import into cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "down-regulation of leucine import into cell" EXACT [GOC:TermGenie] +synonym: "downregulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "downregulation of leucine import into cell" EXACT [GOC:TermGenie] +synonym: "inhibition of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "inhibition of leucine import into cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of leucine import into cell" EXACT [] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1905532 ! regulation of leucine import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098713 ! leucine import across plasma membrane +relationship: negatively_regulates GO:0098713 ! leucine import across plasma membrane +created_by: vw +creation_date: 2016-10-05T21:08:01Z + +[Term] +id: GO:1905534 +name: positive regulation of leucine import across plasma membrane +namespace: biological_process +alt_id: GO:1903130 +def: "Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:10467003] +synonym: "activation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "activation of leucine import into cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of leucine import into cell" EXACT [] +synonym: "up regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "up regulation of leucine import into cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "up-regulation of leucine import into cell" EXACT [GOC:TermGenie] +synonym: "upregulation of L-leucine import into cell" NARROW [GOC:TermGenie] +synonym: "upregulation of leucine import into cell" EXACT [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:1905532 ! regulation of leucine import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098713 ! leucine import across plasma membrane +relationship: positively_regulates GO:0098713 ! leucine import across plasma membrane +created_by: vw +creation_date: 2014-06-25T13:10:04Z + +[Term] +id: GO:1905535 +name: regulation of eukaryotic translation initiation factor 4F complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "regulation of eIF4F assembly" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +relationship: regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +created_by: bc +creation_date: 2016-10-06T14:04:58Z + +[Term] +id: GO:1905536 +name: negative regulation of eukaryotic translation initiation factor 4F complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "down regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of eIF-4F assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of eIF4F assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of eukaryotic translation initiation factor 4F complex assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of eIF4F assembly" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1905535 ! regulation of eukaryotic translation initiation factor 4F complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +relationship: negatively_regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +created_by: bc +creation_date: 2016-10-06T14:05:06Z + +[Term] +id: GO:1905537 +name: positive regulation of eukaryotic translation initiation factor 4F complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "activation of eIF-4F assembly" NARROW [GOC:TermGenie] +synonym: "activation of eIF4F assembly" NARROW [GOC:TermGenie] +synonym: "activation of eukaryotic translation initiation factor 4F complex assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of eIF-4F assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of eIF4F assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of eukaryotic translation initiation factor 4F complex assembly" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1905535 ! regulation of eukaryotic translation initiation factor 4F complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +relationship: positively_regulates GO:0097010 ! eukaryotic translation initiation factor 4F complex assembly +created_by: bc +creation_date: 2016-10-06T14:05:13Z + +[Term] +id: GO:1905538 +name: polysome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a polysome." [GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "polyribosome binding" EXACT [GOC:TermGenie] +is_a: GO:0043021 ! ribonucleoprotein complex binding +created_by: bc +creation_date: 2016-10-07T14:02:53Z + +[Term] +id: GO:1905539 +name: regulation of postsynapse to nucleus signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway." [GO_REF:0000058, GOC:TermGenie, ISBN:9780071120005] +subset: goslim_synapse +synonym: "regulation of postsynaptic signaling to nucleus" EXACT [GOC:TermGenie] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099527 ! postsynapse to nucleus signaling pathway +relationship: regulates GO:0099527 ! postsynapse to nucleus signaling pathway +created_by: dos +creation_date: 2016-10-07T17:03:38Z + +[Term] +id: GO:1905540 +name: interleukin-7 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:19141282] +comment: An example of this is IL7R in human (P16871) in PMID:19141282 (inferred from direct assay). +synonym: "IL-7 receptor complex" EXACT [] +synonym: "IL-7-receptor complex" EXACT [] +synonym: "IL7 receptor complex" EXACT [] +synonym: "IL7-receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +created_by: bhm +creation_date: 2016-10-10T07:44:05Z + +[Term] +id: GO:1905541 +name: regulation of L-arginine import across plasma membrane +namespace: biological_process +alt_id: GO:1902826 +def: "Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:14718525] +synonym: "regulation of L-arginine import into cell" EXACT [] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:0010963 ! regulation of L-arginine import +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097638 ! L-arginine import across plasma membrane +relationship: regulates GO:0097638 ! L-arginine import across plasma membrane +creation_date: 2014-03-31T14:30:40Z + +[Term] +id: GO:1905542 +name: negative regulation of L-arginine import across plasma membrane +namespace: biological_process +alt_id: GO:1902827 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:14718525] +synonym: "down regulation of L-arginine import into cell" EXACT [GOC:TermGenie] +synonym: "downregulation of L-arginine import into cell" EXACT [GOC:TermGenie] +synonym: "inhibition of L-arginine import into cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of L-arginine import into cell" EXACT [] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1905541 ! regulation of L-arginine import across plasma membrane +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097638 ! L-arginine import across plasma membrane +relationship: negatively_regulates GO:0097638 ! L-arginine import across plasma membrane +created_by: mah +creation_date: 2014-03-31T14:30:46Z + +[Term] +id: GO:1905543 +name: interleukin-15 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:23104097] +comment: An example of this is IL15RA in human (Q13261) in PMID:23104097 (inferred from physical interaction). +synonym: "IL-15 receptor complex" EXACT [] +synonym: "IL-15-receptor complex" EXACT [] +synonym: "IL15 receptor complex" EXACT [] +synonym: "IL15-receptor complex" EXACT [] +synonym: "interleukin-15-receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +created_by: bhm +creation_date: 2016-10-10T13:38:12Z + +[Term] +id: GO:1905544 +name: L-methionine import across plasma membrane +namespace: biological_process +alt_id: GO:1903813 +def: "The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol." [GO_REF:0000075, GOC:TermGenie, PMID:17556368] +synonym: "L-methionine import into cell" EXACT [] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:1902475 ! L-alpha-amino acid transmembrane transport +is_a: GO:1903692 ! methionine import across plasma membrane +created_by: mah +creation_date: 2015-01-16T15:03:17Z + +[Term] +id: GO:1905545 +name: obsolete negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron." [GO_REF:0000058, GOC:TermGenie, PMID:20435771] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron" EXACT [GOC:TermGenie] +synonym: "negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: al +creation_date: 2016-10-11T16:15:05Z + +[Term] +id: GO:1905546 +name: cellular response to phenylpropanoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22700048] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0080184 ! response to phenylpropanoid +created_by: sl +creation_date: 2016-10-11T19:54:58Z + +[Term] +id: GO:1905547 +name: regulation of subtelomeric heterochromatin assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of subtelomeric heterochromatin assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25819580] +synonym: "regulation of telomeric heterochromatin assembly" RELATED [] +synonym: "regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +is_a: GO:0031445 ! regulation of heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031509 ! subtelomeric heterochromatin assembly +relationship: regulates GO:0031509 ! subtelomeric heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19188 xsd:anyURI +created_by: nc +creation_date: 2016-10-12T11:14:00Z + +[Term] +id: GO:1905548 +name: negative regulation of subtelomeric heterochromatin assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25819580] +synonym: "down regulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "downregulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "inhibition of telomeric heterochromatin assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of telomeric heterochromatin formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomeric heterochromatin assembly" RELATED [] +synonym: "negative regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +is_a: GO:0031452 ! negative regulation of heterochromatin assembly +is_a: GO:1905547 ! regulation of subtelomeric heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031509 ! subtelomeric heterochromatin assembly +relationship: negatively_regulates GO:0031509 ! subtelomeric heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19188 xsd:anyURI +created_by: nc +creation_date: 2016-10-12T11:18:23Z + +[Term] +id: GO:1905549 +name: positive regulation of subtelomeric heterochromatin assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of subtelomeric heterochromatin assembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:25819580] +synonym: "activation of telomeric heterochromatin assembly" NARROW [GOC:TermGenie] +synonym: "activation of telomeric heterochromatin formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomeric heterochromatin assembly" RELATED [] +synonym: "positive regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "up regulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +synonym: "upregulation of telomeric heterochromatin assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of telomeric heterochromatin formation" RELATED [GOC:TermGenie] +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:1905547 ! regulation of subtelomeric heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031509 ! subtelomeric heterochromatin assembly +relationship: positively_regulates GO:0031509 ! subtelomeric heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19188 xsd:anyURI +created_by: nc +creation_date: 2016-10-12T11:18:30Z + +[Term] +id: GO:1905550 +name: regulation of protein localization to endoplasmic reticulum +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum." [GO_REF:0000058, GOC:TermGenie, PMID:22768340] +synonym: "regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in ER" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070972 ! protein localization to endoplasmic reticulum +relationship: regulates GO:0070972 ! protein localization to endoplasmic reticulum +created_by: rz +creation_date: 2016-10-12T11:37:01Z + +[Term] +id: GO:1905551 +name: negative regulation of protein localization to endoplasmic reticulum +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum." [GO_REF:0000058, GOC:TermGenie, PMID:22768340] +synonym: "down regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in ER" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in ER" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905550 ! regulation of protein localization to endoplasmic reticulum +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070972 ! protein localization to endoplasmic reticulum +relationship: negatively_regulates GO:0070972 ! protein localization to endoplasmic reticulum +created_by: rz +creation_date: 2016-10-12T11:37:08Z + +[Term] +id: GO:1905552 +name: positive regulation of protein localization to endoplasmic reticulum +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum." [GO_REF:0000058, GOC:TermGenie, PMID:22768340] +synonym: "activation of protein localisation in endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in ER" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to endoplasmic reticulum" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in endoplasmic reticulum" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in ER" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to endoplasmic reticulum" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905550 ! regulation of protein localization to endoplasmic reticulum +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070972 ! protein localization to endoplasmic reticulum +relationship: positively_regulates GO:0070972 ! protein localization to endoplasmic reticulum +created_by: rz +creation_date: 2016-10-12T11:37:16Z + +[Term] +id: GO:1905553 +name: regulation of blood vessel branching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0045765 ! regulation of angiogenesis +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001569 ! branching involved in blood vessel morphogenesis +relationship: regulates GO:0001569 ! branching involved in blood vessel morphogenesis +created_by: nc +creation_date: 2016-10-12T14:19:33Z + +[Term] +id: GO:1905554 +name: negative regulation of vessel branching +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "inhibition of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of patterning of blood vessels" NARROW [GOC:TermGenie] +synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0016525 ! negative regulation of angiogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:1905553 ! regulation of blood vessel branching +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis +relationship: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis +created_by: nc +creation_date: 2016-10-12T14:19:41Z + +[Term] +id: GO:1905555 +name: positive regulation blood vessel branching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +synonym: "activation of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of patterning of blood vessels" NARROW [GOC:TermGenie] +synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] +synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie] +is_a: GO:0045766 ! positive regulation of angiogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +is_a: GO:1905553 ! regulation of blood vessel branching +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis +relationship: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis +created_by: nc +creation_date: 2016-10-12T14:19:49Z + +[Term] +id: GO:1905556 +name: ciliary vesicle assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:13978319, PMID:25313408, PMID:25805133, PMID:25812525] +synonym: "ciliary vesicle formation" EXACT [GOC:TermGenie] +synonym: "CV assembly" RELATED [GOC:TermGenie] +synonym: "CV formation" RELATED [GOC:TermGenie] +synonym: "primary ciliary vesicle assembly" EXACT [GOC:TermGenie] +synonym: "primary ciliary vesicle formation" EXACT [GOC:TermGenie] +is_a: GO:0016050 ! vesicle organization +is_a: GO:0070925 ! organelle assembly +created_by: pr +creation_date: 2016-10-13T09:31:06Z + +[Term] +id: GO:1905557 +name: regulation of mitotic nuclear envelope disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] +synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +is_a: GO:0007346 ! regulation of mitotic cell cycle +is_a: GO:0010549 ! regulation of membrane disassembly +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:1903353 ! regulation of nucleus organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007077 ! mitotic nuclear envelope disassembly +relationship: regulates GO:0007077 ! mitotic nuclear envelope disassembly +created_by: hbye +creation_date: 2016-10-14T13:14:57Z + +[Term] +id: GO:1905558 +name: negative regulation of mitotic nuclear envelope disassembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] +synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] +synonym: "inhibition of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0045930 ! negative regulation of mitotic cell cycle +is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007077 ! mitotic nuclear envelope disassembly +relationship: negatively_regulates GO:0007077 ! mitotic nuclear envelope disassembly +created_by: hbye +creation_date: 2016-10-14T13:15:08Z + +[Term] +id: GO:1905559 +name: positive regulation of mitotic nuclear envelope disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] +synonym: "activation of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] +synonym: "activation of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] +synonym: "activation of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] +synonym: "activation of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0045931 ! positive regulation of mitotic cell cycle +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007077 ! mitotic nuclear envelope disassembly +relationship: positively_regulates GO:0007077 ! mitotic nuclear envelope disassembly +created_by: hbye +creation_date: 2016-10-14T13:15:17Z + +[Term] +id: GO:1905560 +name: negative regulation of kinetochore assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] +synonym: "down regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "down regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "down regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "down regulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of kinetochore biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "down-regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "down-regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "down-regulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "downregulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "downregulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "downregulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "downregulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "inhibition of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "inhibition of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "inhibition of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "inhibition of kinetochore assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "negative regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "negative regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "negative regulation of kinetochore formation" RELATED [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:0090234 ! regulation of kinetochore assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +is_a: GO:2001251 ! negative regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051382 ! kinetochore assembly +relationship: negatively_regulates GO:0051382 ! kinetochore assembly +created_by: hbye +creation_date: 2016-10-14T13:47:38Z + +[Term] +id: GO:1905561 +name: positive regulation of kinetochore assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of kinetochore assembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] +synonym: "activation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "activation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "activation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "activation of kinetochore assembly" NARROW [GOC:TermGenie] +synonym: "activation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "positive regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "positive regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "positive regulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "up regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "up regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "up regulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "up-regulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "up-regulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "up-regulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of kinetochore formation" RELATED [GOC:TermGenie] +synonym: "upregulation of centromere and kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "upregulation of centromere/kinetochore complex maturation" NARROW [GOC:TermGenie] +synonym: "upregulation of chromosome-kinetochore attachment" NARROW [GOC:TermGenie] +synonym: "upregulation of kinetochore assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of kinetochore formation" RELATED [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:0090234 ! regulation of kinetochore assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051382 ! kinetochore assembly +relationship: positively_regulates GO:0051382 ! kinetochore assembly +created_by: hbye +creation_date: 2016-10-14T13:47:45Z + +[Term] +id: GO:1905562 +name: regulation of vascular endothelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +is_a: GO:0001936 ! regulation of endothelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0101023 ! vascular endothelial cell proliferation +relationship: regulates GO:0101023 ! vascular endothelial cell proliferation +created_by: nc +creation_date: 2016-10-17T09:24:17Z + +[Term] +id: GO:1905563 +name: negative regulation of vascular endothelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0001937 ! negative regulation of endothelial cell proliferation +is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation +relationship: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation +created_by: nc +creation_date: 2016-10-17T09:24:26Z + +[Term] +id: GO:1905564 +name: positive regulation of vascular endothelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] +synonym: "activation of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0001938 ! positive regulation of endothelial cell proliferation +is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0101023 ! vascular endothelial cell proliferation +relationship: positively_regulates GO:0101023 ! vascular endothelial cell proliferation +created_by: nc +creation_date: 2016-10-17T09:24:35Z + +[Term] +id: GO:1905565 +name: obsolete regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: nc +creation_date: 2016-10-18T10:58:29Z + +[Term] +id: GO:1905566 +name: obsolete negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of LDL" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +is_obsolete: true +created_by: nc +creation_date: 2016-10-18T10:58:46Z + +[Term] +id: GO:1905567 +name: obsolete positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "activation of receptor-mediated endocytosis of LDL" NARROW [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of LDL" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: nc +creation_date: 2016-10-18T10:58:54Z + +[Term] +id: GO:1905568 +name: regulation of ferrichrome biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process." [GO_REF:0000058, GOC:al, GOC:TermGenie] +synonym: "regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +is_a: GO:0062012 ! regulation of small molecule metabolic process +is_a: GO:1900704 ! regulation of siderophore biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031169 ! ferrichrome biosynthetic process +relationship: regulates GO:0031169 ! ferrichrome biosynthetic process +created_by: pr +creation_date: 2016-10-18T14:49:00Z + +[Term] +id: GO:1905569 +name: negative regulation of ferrichrome biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process." [GO_REF:0000058, GOC:al, GOC:TermGenie, PMID:654321] +synonym: "down regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "down-regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "downregulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "downregulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of ferrichrome anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ferrichrome synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "negative regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:1900705 ! negative regulation of siderophore biosynthetic process +is_a: GO:1905568 ! regulation of ferrichrome biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031169 ! ferrichrome biosynthetic process +relationship: negatively_regulates GO:0031169 ! ferrichrome biosynthetic process +created_by: pr +creation_date: 2016-10-18T14:49:08Z + +[Term] +id: GO:1905570 +name: positive regulation of ferrichrome biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process." [GO_REF:0000058, GOC:al, GOC:TermGenie, PMID:654321] +synonym: "activation of ferrichrome anabolism" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome formation" NARROW [GOC:TermGenie] +synonym: "activation of ferrichrome synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "positive regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "up-regulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrichrome anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrichrome biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrichrome biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrichrome biosynthetic process, peptide formation" NARROW [GOC:TermGenie] +synonym: "upregulation of ferrichrome biosynthetic process, peptide modification" NARROW [GOC:TermGenie] +synonym: "upregulation of ferrichrome formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ferrichrome synthesis" EXACT [GOC:TermGenie] +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:1900706 ! positive regulation of siderophore biosynthetic process +is_a: GO:1905568 ! regulation of ferrichrome biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031169 ! ferrichrome biosynthetic process +relationship: positively_regulates GO:0031169 ! ferrichrome biosynthetic process +created_by: pr +creation_date: 2016-10-18T14:49:16Z + +[Term] +id: GO:1905571 +name: interleukin-10 receptor complex +namespace: cellular_component +def: "A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16982608] +comment: An example of this is IL10RA in human (UniProt symbol Q13651) in PMID:16982608 (inferred from physical interaction). +synonym: "IL-10 receptor complex" EXACT [] +synonym: "IL-10-receptor complex" EXACT [] +synonym: "IL10 receptor complex" EXACT [] +synonym: "interleukin-10-receptor complex" EXACT [] +is_a: GO:0043235 ! receptor complex +created_by: bhm +creation_date: 2016-10-19T09:45:22Z + +[Term] +id: GO:1905572 +name: ganglioside GM1 transport to membrane +namespace: biological_process +def: "The directed movement of ganglioside GM1 to membrane." [GO_REF:0000078, GOC:TermGenie, PMID:1454804] +is_a: GO:0035627 ! ceramide transport +is_a: GO:0046836 ! glycolipid transport +is_a: GO:0046942 ! carboxylic acid transport +created_by: pga +creation_date: 2016-10-19T10:50:44Z + +[Term] +id: GO:1905573 +name: ganglioside GM1 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ganglioside GM1." [GO_REF:0000067, GOC:TermGenie, PMID:1454804] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0035594 ! ganglioside binding +created_by: pga +creation_date: 2016-10-19T10:57:28Z + +[Term] +id: GO:1905574 +name: ganglioside GM2 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ganglioside GM2." [GO_REF:0000067, GOC:TermGenie, PMID:1454804] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0035594 ! ganglioside binding +created_by: pga +creation_date: 2016-10-19T11:17:01Z + +[Term] +id: GO:1905575 +name: ganglioside GM3 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ganglioside GM3." [GO_REF:0000067, GOC:TermGenie, PMID:1454804] +is_a: GO:0033293 ! monocarboxylic acid binding +is_a: GO:0035594 ! ganglioside binding +created_by: pga +creation_date: 2016-10-19T11:17:10Z + +[Term] +id: GO:1905576 +name: ganglioside GT1b binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ganglioside GT1b." [GO_REF:0000067, GOC:TermGenie, PMID:1454804] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0035594 ! ganglioside binding +created_by: pga +creation_date: 2016-10-19T11:17:17Z + +[Term] +id: GO:1905577 +name: ganglioside GP1c binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with ganglioside GP1c." [GO_REF:0000067, GOC:TermGenie, PMID:1454804] +is_a: GO:0031406 ! carboxylic acid binding +is_a: GO:0035594 ! ganglioside binding +created_by: pga +creation_date: 2016-10-19T11:17:25Z + +[Term] +id: GO:1905578 +name: regulation of ERBB3 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:27353365] +synonym: "regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1901184 ! regulation of ERBB signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038129 ! ERBB3 signaling pathway +relationship: regulates GO:0038129 ! ERBB3 signaling pathway +created_by: als +creation_date: 2016-10-19T11:46:55Z + +[Term] +id: GO:1905579 +name: negative regulation of ERBB3 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:27353365] +synonym: "down regulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "inhibition of ERBB3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of ERBB3 signalling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of HER3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "negative regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "negative regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1901185 ! negative regulation of ERBB signaling pathway +is_a: GO:1905578 ! regulation of ERBB3 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038129 ! ERBB3 signaling pathway +relationship: negatively_regulates GO:0038129 ! ERBB3 signaling pathway +created_by: als +creation_date: 2016-10-19T11:47:03Z + +[Term] +id: GO:1905580 +name: positive regulation of ERBB3 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:27353365] +synonym: "activation of ERBB3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of ERBB3 signalling pathway" NARROW [GOC:TermGenie] +synonym: "activation of HER3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "activation of receptor tyrosine-protein kinase erbB-3 signaling pathway" NARROW [GOC:TermGenie] +synonym: "positive regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of ERBB3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of ERBB3 signalling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of HER3 signaling pathway" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway" EXACT [GOC:TermGenie] +is_a: GO:1901186 ! positive regulation of ERBB signaling pathway +is_a: GO:1905578 ! regulation of ERBB3 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038129 ! ERBB3 signaling pathway +relationship: positively_regulates GO:0038129 ! ERBB3 signaling pathway +created_by: als +creation_date: 2016-10-19T11:47:11Z + +[Term] +id: GO:1905581 +name: positive regulation of low-density lipoprotein particle clearance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "activation of LDL clearance" NARROW [GOC:TermGenie] +synonym: "activation of low-density lipoprotein particle clearance" NARROW [GOC:TermGenie] +synonym: "positive regulation of LDL clearance" EXACT [GOC:TermGenie] +synonym: "up regulation of LDL clearance" EXACT [GOC:TermGenie] +synonym: "up regulation of low-density lipoprotein particle clearance" EXACT [GOC:TermGenie] +synonym: "up-regulation of LDL clearance" EXACT [GOC:TermGenie] +synonym: "up-regulation of low-density lipoprotein particle clearance" EXACT [GOC:TermGenie] +synonym: "upregulation of LDL clearance" EXACT [GOC:TermGenie] +synonym: "upregulation of low-density lipoprotein particle clearance" EXACT [GOC:TermGenie] +is_a: GO:0010986 ! positive regulation of lipoprotein particle clearance +is_a: GO:0010988 ! regulation of low-density lipoprotein particle clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034383 ! low-density lipoprotein particle clearance +relationship: positively_regulates GO:0034383 ! low-density lipoprotein particle clearance +created_by: nc +creation_date: 2016-10-19T14:39:15Z + +[Term] +id: GO:1905582 +name: response to mannose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16699509] +is_a: GO:0009746 ! response to hexose +created_by: pga +creation_date: 2016-10-21T11:40:40Z + +[Term] +id: GO:1905583 +name: cellular response to mannose +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:16699509] +is_a: GO:0071331 ! cellular response to hexose stimulus +is_a: GO:1905582 ! response to mannose +created_by: pga +creation_date: 2016-10-21T11:40:47Z + +[Term] +id: GO:1905584 +name: outer hair cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in an outer hair cell." [GO_REF:0000085, GOC:TermGenie, PMID:12062759, PMID:24472721] +synonym: "cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "outer hair cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0051402 ! neuron apoptotic process +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: sl +creation_date: 2016-10-21T22:42:13Z + +[Term] +id: GO:1905585 +name: regulation of outer hair cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24472721] +synonym: "regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0043523 ! regulation of neuron apoptotic process +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905584 ! outer hair cell apoptotic process +relationship: regulates GO:1905584 ! outer hair cell apoptotic process +created_by: sl +creation_date: 2016-10-24T22:35:34Z + +[Term] +id: GO:1905586 +name: negative regulation of outer hair cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24472721] +synonym: "down regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down regulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "down-regulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "downregulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "downregulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "inhibition of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of cochlear outer hair cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "inhibition of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "inhibition of outer hair cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "negative regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "negative regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "negative regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:1905585 ! regulation of outer hair cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905584 ! outer hair cell apoptotic process +relationship: negatively_regulates GO:1905584 ! outer hair cell apoptotic process +created_by: sl +creation_date: 2016-10-24T22:35:43Z + +[Term] +id: GO:1905587 +name: positive regulation of outer hair cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24472721] +synonym: "activation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of cochlear outer hair cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "activation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "activation of outer hair cell apoptotic process" NARROW [GOC:TermGenie] +synonym: "positive regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "positive regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "positive regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up regulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "up-regulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of cochlear outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of cochlear outer hair cell apoptotic process" EXACT [GOC:TermGenie] +synonym: "upregulation of outer hair cell apoptosis" NARROW [GOC:TermGenie] +synonym: "upregulation of outer hair cell apoptotic process" EXACT [GOC:TermGenie] +is_a: GO:0043525 ! positive regulation of neuron apoptotic process +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:1905585 ! regulation of outer hair cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905584 ! outer hair cell apoptotic process +relationship: positively_regulates GO:1905584 ! outer hair cell apoptotic process +created_by: sl +creation_date: 2016-10-24T22:35:51Z + +[Term] +id: GO:1905588 +name: plant-type cell wall modification involved in stomatal movement +namespace: biological_process +def: "Any plant-type cell wall modification that is involved in stomatal movement." [GO_REF:0000060, GOC:TermGenie, PMID:27720618] +synonym: "cellulose and pectin-containing cell wall modification involved in stomatal movement" EXACT [GOC:TermGenie] +is_a: GO:0009827 ! plant-type cell wall modification +intersection_of: GO:0009827 ! plant-type cell wall modification +intersection_of: part_of GO:0010118 ! stomatal movement +relationship: part_of GO:0010118 ! stomatal movement +created_by: lr +creation_date: 2016-10-25T00:29:26Z + +[Term] +id: GO:1905589 +name: positive regulation of L-arginine import across plasma membrane +namespace: biological_process +alt_id: GO:1901042 +alt_id: GO:1902828 +def: "Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:14718525] +synonym: "activation of L-arginine import" NARROW [GOC:TermGenie] +synonym: "activation of L-arginine import across plasma membrane" NARROW [GOC:TermGenie] +synonym: "activation of L-arginine import into cell" NARROW [GOC:TermGenie] +synonym: "activation of L-arginine uptake" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-arginine import" BROAD [] +synonym: "positive regulation of L-arginine import into cell" EXACT [] +synonym: "positive regulation of L-arginine uptake" EXACT [GOC:TermGenie] +synonym: "up regulation of L-arginine import" EXACT [GOC:TermGenie] +synonym: "up regulation of L-arginine uptake" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-arginine import" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-arginine import into cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-arginine uptake" EXACT [GOC:TermGenie] +synonym: "upregulation of L-arginine import" EXACT [GOC:TermGenie] +synonym: "upregulation of L-arginine import into cell" EXACT [GOC:TermGenie] +synonym: "upregulation of L-arginine uptake" EXACT [GOC:TermGenie] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:1905541 ! regulation of L-arginine import across plasma membrane +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097638 ! L-arginine import across plasma membrane +relationship: positively_regulates GO:0097638 ! L-arginine import across plasma membrane +created_by: al +creation_date: 2012-06-25T12:27:24Z + +[Term] +id: GO:1905590 +name: fibronectin fibril organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril." [GOC:dph, GOC:TermGenie, PMID:20690820] +is_a: GO:0097435 ! supramolecular fiber organization +created_by: dph +creation_date: 2016-10-25T12:04:50Z + +[Term] +id: GO:1905591 +name: regulation of optical nerve axon regeneration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of optical nerve axon regeneration." [GO_REF:0000058, GOC:TermGenie, PMID:16699509] +is_a: GO:0048679 ! regulation of axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0101027 ! optical nerve axon regeneration +relationship: regulates GO:0101027 ! optical nerve axon regeneration +created_by: pga +creation_date: 2016-10-25T12:58:43Z + +[Term] +id: GO:1905592 +name: negative regulation of optical nerve axon regeneration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration." [GO_REF:0000058, GOC:TermGenie, PMID:16699509] +synonym: "down regulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +synonym: "down-regulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +synonym: "downregulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +synonym: "inhibition of optical nerve axon regeneration" NARROW [GOC:TermGenie] +is_a: GO:0048681 ! negative regulation of axon regeneration +is_a: GO:1905591 ! regulation of optical nerve axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0101027 ! optical nerve axon regeneration +relationship: negatively_regulates GO:0101027 ! optical nerve axon regeneration +created_by: pga +creation_date: 2016-10-25T12:58:50Z + +[Term] +id: GO:1905593 +name: positive regulation of optical nerve axon regeneration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration." [GO_REF:0000058, GOC:TermGenie, PMID:16699509] +synonym: "activation of optical nerve axon regeneration" NARROW [GOC:TermGenie] +synonym: "up regulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +synonym: "up-regulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +synonym: "upregulation of optical nerve axon regeneration" EXACT [GOC:TermGenie] +is_a: GO:0048680 ! positive regulation of axon regeneration +is_a: GO:1905591 ! regulation of optical nerve axon regeneration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0101027 ! optical nerve axon regeneration +relationship: positively_regulates GO:0101027 ! optical nerve axon regeneration +created_by: pga +creation_date: 2016-10-25T12:58:58Z + +[Term] +id: GO:1905594 +name: resveratrol binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with resveratrol." [GO_REF:0000067, GOC:TermGenie, PMID:18254726] +comment: (5-(aziridin-1-yl)-2,4-dinitrobenzamide +is_a: GO:0097159 ! organic cyclic compound binding +created_by: pga +creation_date: 2016-10-25T15:23:37Z + +[Term] +id: GO:1905595 +name: regulation of low-density lipoprotein particle receptor binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +is_a: GO:1900120 ! regulation of receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050750 ! low-density lipoprotein particle receptor binding +relationship: regulates GO:0050750 ! low-density lipoprotein particle receptor binding +created_by: nc +creation_date: 2016-10-26T10:57:23Z + +[Term] +id: GO:1905596 +name: negative regulation of low-density lipoprotein particle receptor binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "down regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "down regulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "down regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "downregulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "inhibition of LDL receptor binding" NARROW [GOC:TermGenie] +synonym: "inhibition of low-density lipoprotein particle receptor binding" NARROW [GOC:TermGenie] +synonym: "inhibition of low-density lipoprotein receptor binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "negative regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +is_a: GO:1900121 ! negative regulation of receptor binding +is_a: GO:1905595 ! regulation of low-density lipoprotein particle receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050750 ! low-density lipoprotein particle receptor binding +relationship: negatively_regulates GO:0050750 ! low-density lipoprotein particle receptor binding +created_by: nc +creation_date: 2016-10-26T10:57:31Z + +[Term] +id: GO:1905597 +name: positive regulation of low-density lipoprotein particle receptor binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "activation of LDL receptor binding" NARROW [GOC:TermGenie] +synonym: "activation of low-density lipoprotein particle receptor binding" NARROW [GOC:TermGenie] +synonym: "activation of low-density lipoprotein receptor binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "positive regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "up regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "up regulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "up regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of LDL receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of low-density lipoprotein particle receptor binding" EXACT [GOC:TermGenie] +synonym: "upregulation of low-density lipoprotein receptor binding" EXACT [GOC:TermGenie] +is_a: GO:1900122 ! positive regulation of receptor binding +is_a: GO:1905595 ! regulation of low-density lipoprotein particle receptor binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050750 ! low-density lipoprotein particle receptor binding +relationship: positively_regulates GO:0050750 ! low-density lipoprotein particle receptor binding +created_by: nc +creation_date: 2016-10-26T10:57:40Z + +[Term] +id: GO:1905598 +name: negative regulation of low-density lipoprotein receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "down regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "down regulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "down regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "down-regulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +synonym: "downregulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "downregulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "downregulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +synonym: "inhibition of LDL receptor" NARROW [GOC:TermGenie] +synonym: "inhibition of LDLR activity" NARROW [GOC:TermGenie] +synonym: "inhibition of low-density lipoprotein receptor activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "negative regulation of LDLR activity" EXACT [GOC:TermGenie] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0045806 ! negative regulation of endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005041 ! low-density lipoprotein particle receptor activity +relationship: negatively_regulates GO:0005041 ! low-density lipoprotein particle receptor activity +created_by: nc +creation_date: 2016-10-26T11:53:34Z + +[Term] +id: GO:1905599 +name: positive regulation of low-density lipoprotein receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "activation of LDL receptor" NARROW [GOC:TermGenie] +synonym: "activation of LDLR activity" NARROW [GOC:TermGenie] +synonym: "activation of low-density lipoprotein receptor activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "positive regulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "up regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "up regulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "up regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "up-regulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +synonym: "upregulation of LDL receptor" EXACT [GOC:TermGenie] +synonym: "upregulation of LDLR activity" EXACT [GOC:TermGenie] +synonym: "upregulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:0045807 ! positive regulation of endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005041 ! low-density lipoprotein particle receptor activity +relationship: positively_regulates GO:0005041 ! low-density lipoprotein particle receptor activity +created_by: nc +creation_date: 2016-10-26T11:53:41Z + +[Term] +id: GO:1905600 +name: regulation of receptor-mediated endocytosis involved in cholesterol transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +is_a: GO:0032383 ! regulation of intracellular cholesterol transport +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +relationship: regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +created_by: pr +creation_date: 2016-10-26T13:01:45Z + +[Term] +id: GO:1905601 +name: negative regulation of receptor-mediated endocytosis involved in cholesterol transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "down regulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis involved in cholesterol transport" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of LDL" NARROW [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +is_a: GO:0032384 ! negative regulation of intracellular cholesterol transport +is_a: GO:0048261 ! negative regulation of receptor-mediated endocytosis +is_a: GO:1905600 ! regulation of receptor-mediated endocytosis involved in cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +relationship: negatively_regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +created_by: pr +creation_date: 2016-10-26T13:01:52Z + +[Term] +id: GO:1905602 +name: positive regulation of receptor-mediated endocytosis involved in cholesterol transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] +synonym: "activation of receptor-mediated endocytosis involved in cholesterol transport" NARROW [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis of LDL" NARROW [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis involved in cholesterol transport" EXACT [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of LDL" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport" RELATED [GOC:TermGenie] +synonym: "upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport" RELATED [GOC:TermGenie] +is_a: GO:0032385 ! positive regulation of intracellular cholesterol transport +is_a: GO:0048260 ! positive regulation of receptor-mediated endocytosis +is_a: GO:1905600 ! regulation of receptor-mediated endocytosis involved in cholesterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +relationship: positively_regulates GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport +created_by: pr +creation_date: 2016-10-26T13:01:59Z + +[Term] +id: GO:1905603 +name: regulation of blood-brain barrier permeability +namespace: biological_process +def: "Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain." [GO_REF:0000058, GOC:als, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:22524708, PMID:30280653] +synonym: "regulation of BBB permeability" EXACT [] +synonym: "regulation of blood/brain barrier permeability" EXACT [] +is_a: GO:0043114 ! regulation of vascular permeability +relationship: part_of GO:0035633 ! maintenance of blood-brain barrier +created_by: als +creation_date: 2016-10-26T13:18:16Z + +[Term] +id: GO:1905604 +name: negative regulation of blood-brain barrier permeability +namespace: biological_process +def: "Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain." [GO_REF:0000058, GOC:als, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:22524708, PMID:30280653] +synonym: "down-regulation of BBB permeability" EXACT [] +synonym: "down-regulation of blood-brain barrier permeability" EXACT [] +synonym: "down-regulation of blood/brain barrier permeability" EXACT [] +synonym: "downregulation of BBB permeability" EXACT [] +synonym: "downregulation of blood-brain barrier permeability" EXACT [] +synonym: "downregulation of blood/brain barrier permeability" EXACT [] +synonym: "inhibition of maintenance of permeability of BBB" NARROW [GOC:TermGenie] +synonym: "inhibition of maintenance of permeability of blood-brain barrier" NARROW [GOC:TermGenie] +synonym: "negative regulation of BBB permeability" EXACT [] +synonym: "negative regulation of blood/brain barrier permeability" EXACT [] +is_a: GO:0043116 ! negative regulation of vascular permeability +is_a: GO:1905603 ! regulation of blood-brain barrier permeability +created_by: als +creation_date: 2016-10-26T13:18:25Z + +[Term] +id: GO:1905605 +name: positive regulation of blood-brain barrier permeability +namespace: biological_process +def: "Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain." [GO_REF:0000058, GOC:als, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:22524708, PMID:30280653] +synonym: "activation of maintenance of permeability of BBB" NARROW [GOC:TermGenie] +synonym: "activation of maintenance of permeability of blood-brain barrier" NARROW [GOC:TermGenie] +synonym: "positive regulation of BBB permeability" EXACT [] +synonym: "positive regulation of blood/brain barrier permeability" EXACT [] +synonym: "up-regulation of BBB permeability" EXACT [] +synonym: "up-regulation of blood-brain barrier permeability" EXACT [] +synonym: "up-regulation of blood/brain barrier permeability" EXACT [] +synonym: "upregulation of BBB permeability" EXACT [] +synonym: "upregulation of blood-brain barrier permeability" EXACT [] +synonym: "upregulation of blood/brain barrier permeability" EXACT [] +is_a: GO:0043117 ! positive regulation of vascular permeability +is_a: GO:1905603 ! regulation of blood-brain barrier permeability +created_by: als +creation_date: 2016-10-26T13:18:32Z + +[Term] +id: GO:1905606 +name: regulation of presynapse assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] +subset: goslim_synapse +synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +is_a: GO:0051963 ! regulation of synapse assembly +is_a: GO:0099174 ! regulation of presynapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099054 ! presynapse assembly +relationship: regulates GO:0099054 ! presynapse assembly +created_by: bc +creation_date: 2016-10-27T16:08:13Z + +[Term] +id: GO:1905607 +name: negative regulation of presynapse assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] +synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "inhibition of presynapse assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of presynapse biogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of presynaptic terminal assembly" NARROW [GOC:TermGenie] +synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +is_a: GO:0051964 ! negative regulation of synapse assembly +is_a: GO:1905606 ! regulation of presynapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0099054 ! presynapse assembly +relationship: negatively_regulates GO:0099054 ! presynapse assembly +created_by: bc +creation_date: 2016-10-27T16:08:20Z + +[Term] +id: GO:1905608 +name: positive regulation of presynapse assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] +synonym: "activation of presynapse assembly" NARROW [GOC:TermGenie] +synonym: "activation of presynapse biogenesis" NARROW [GOC:TermGenie] +synonym: "activation of presynaptic terminal assembly" NARROW [GOC:TermGenie] +synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] +is_a: GO:0051965 ! positive regulation of synapse assembly +is_a: GO:1905606 ! regulation of presynapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099054 ! presynapse assembly +relationship: positively_regulates GO:0099054 ! presynapse assembly +created_by: bc +creation_date: 2016-10-27T16:08:28Z + +[Term] +id: GO:1905609 +name: positive regulation of smooth muscle cell-matrix adhesion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion." [GO_REF:0000058, GOC:TermGenie, PMID:14970114] +synonym: "activation of smooth muscle cell-matrix adhesion" NARROW [GOC:TermGenie] +synonym: "up regulation of smooth muscle cell-matrix adhesion" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle cell-matrix adhesion" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle cell-matrix adhesion" EXACT [GOC:TermGenie] +is_a: GO:0001954 ! positive regulation of cell-matrix adhesion +is_a: GO:2000097 ! regulation of smooth muscle cell-matrix adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061302 ! smooth muscle cell-matrix adhesion +relationship: positively_regulates GO:0061302 ! smooth muscle cell-matrix adhesion +created_by: sl +creation_date: 2016-10-27T21:58:11Z + +[Term] +id: GO:1905610 +name: regulation of mRNA cap binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA cap binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +is_a: GO:1902415 ! regulation of mRNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098808 ! mRNA cap binding +relationship: regulates GO:0098808 ! mRNA cap binding +created_by: bc +creation_date: 2016-10-28T11:27:28Z + +[Term] +id: GO:1905611 +name: negative regulation of mRNA cap binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +synonym: "down regulation of mRNA cap binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of mRNA cap binding" EXACT [GOC:TermGenie] +synonym: "downregulation of mRNA cap binding" EXACT [GOC:TermGenie] +synonym: "inhibition of mRNA cap binding" NARROW [GOC:TermGenie] +is_a: GO:1904572 ! negative regulation of mRNA binding +is_a: GO:1905610 ! regulation of mRNA cap binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098808 ! mRNA cap binding +relationship: negatively_regulates GO:0098808 ! mRNA cap binding +created_by: bc +creation_date: 2016-10-28T11:27:36Z + +[Term] +id: GO:1905612 +name: positive regulation of mRNA cap binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA cap binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +synonym: "activation of mRNA cap binding" NARROW [GOC:TermGenie] +synonym: "up regulation of mRNA cap binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of mRNA cap binding" EXACT [GOC:TermGenie] +synonym: "upregulation of mRNA cap binding" EXACT [GOC:TermGenie] +is_a: GO:1902416 ! positive regulation of mRNA binding +is_a: GO:1905610 ! regulation of mRNA cap binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098808 ! mRNA cap binding +relationship: positively_regulates GO:0098808 ! mRNA cap binding +created_by: bc +creation_date: 2016-10-28T11:27:43Z + +[Term] +id: GO:1905613 +name: regulation of developmental vegetative growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of developmental vegetative growth." [GO_REF:0000058, GOC:TermGenie, PMID:11606552] +is_a: GO:0048638 ! regulation of developmental growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080186 ! developmental vegetative growth +relationship: regulates GO:0080186 ! developmental vegetative growth +created_by: pga +creation_date: 2016-10-28T11:45:13Z + +[Term] +id: GO:1905614 +name: negative regulation of developmental vegetative growth +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth." [GO_REF:0000058, GOC:TermGenie, PMID:11606552] +synonym: "down regulation of developmental vegetative growth" EXACT [GOC:TermGenie] +synonym: "down-regulation of developmental vegetative growth" EXACT [GOC:TermGenie] +synonym: "downregulation of developmental vegetative growth" EXACT [GOC:TermGenie] +synonym: "inhibition of developmental vegetative growth" NARROW [GOC:TermGenie] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:1905613 ! regulation of developmental vegetative growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0080186 ! developmental vegetative growth +relationship: negatively_regulates GO:0080186 ! developmental vegetative growth +created_by: pga +creation_date: 2016-10-28T11:45:20Z + +[Term] +id: GO:1905615 +name: positive regulation of developmental vegetative growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of developmental vegetative growth." [GO_REF:0000058, GOC:TermGenie, PMID:11606552] +synonym: "activation of developmental vegetative growth" NARROW [GOC:TermGenie] +synonym: "up regulation of developmental vegetative growth" EXACT [GOC:TermGenie] +synonym: "up-regulation of developmental vegetative growth" EXACT [GOC:TermGenie] +synonym: "upregulation of developmental vegetative growth" EXACT [GOC:TermGenie] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:1905613 ! regulation of developmental vegetative growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0080186 ! developmental vegetative growth +relationship: positively_regulates GO:0080186 ! developmental vegetative growth +created_by: pga +creation_date: 2016-10-28T11:45:28Z + +[Term] +id: GO:1905616 +name: regulation of miRNA mediated inhibition of translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of miRNA mediated inhibition of translation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +synonym: "regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +is_a: GO:0006417 ! regulation of translation +is_a: GO:0060964 ! regulation of gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035278 ! miRNA mediated inhibition of translation +relationship: regulates GO:0035278 ! miRNA mediated inhibition of translation +created_by: bc +creation_date: 2016-10-28T11:47:49Z + +[Term] +id: GO:1905617 +name: negative regulation of miRNA mediated inhibition of translation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of miRNA mediated inhibition of translation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +synonym: "down regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "down regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "down regulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "down regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "down regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "down-regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "down-regulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "down-regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "down-regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "downregulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "downregulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "downregulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "downregulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "inhibition of down regulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "inhibition of down-regulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "inhibition of downregulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "inhibition of gene silencing by miRNA, negative regulation of translation" NARROW [GOC:TermGenie] +synonym: "inhibition of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "inhibition of miRNA mediated inhibition of translation" NARROW [GOC:TermGenie] +synonym: "inhibition of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "inhibition of negative regulation of translation involved in gene silencing by microRNA" NARROW [GOC:TermGenie] +synonym: "negative regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "negative regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "negative regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "negative regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "negative regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "negative regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "negative regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +is_a: GO:0045727 ! positive regulation of translation +is_a: GO:0060965 ! negative regulation of gene silencing by miRNA +is_a: GO:1905616 ! regulation of miRNA mediated inhibition of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035278 ! miRNA mediated inhibition of translation +relationship: negatively_regulates GO:0035278 ! miRNA mediated inhibition of translation +created_by: bc +creation_date: 2016-10-28T11:47:57Z + +[Term] +id: GO:1905618 +name: positive regulation of miRNA mediated inhibition of translation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of miRNA mediated inhibition of translation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23409027] +synonym: "activation of down regulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "activation of down-regulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "activation of downregulation of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "activation of gene silencing by miRNA, negative regulation of translation" NARROW [GOC:TermGenie] +synonym: "activation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "activation of miRNA mediated inhibition of translation" NARROW [GOC:TermGenie] +synonym: "activation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "activation of negative regulation of translation involved in gene silencing by microRNA" NARROW [GOC:TermGenie] +synonym: "positive regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "positive regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "positive regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "positive regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "positive regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "positive regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "positive regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "up regulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "up regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "up regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "up-regulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "up-regulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "up-regulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "up-regulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of down regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of down-regulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of downregulation of translation involved in gene silencing by miRNA" EXACT [GOC:TermGenie] +synonym: "upregulation of gene silencing by miRNA, negative regulation of translation" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibition of translation involved in gene silencing by miRNA" NARROW [GOC:TermGenie] +synonym: "upregulation of miRNA mediated inhibition of translation" EXACT [GOC:TermGenie] +synonym: "upregulation of miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:TermGenie] +synonym: "upregulation of negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:TermGenie] +is_a: GO:1905616 ! regulation of miRNA mediated inhibition of translation +is_a: GO:2000637 ! positive regulation of gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035278 ! miRNA mediated inhibition of translation +relationship: positively_regulates GO:0035278 ! miRNA mediated inhibition of translation +created_by: bc +creation_date: 2016-10-28T11:48:04Z + +[Term] +id: GO:1905619 +name: regulation of alpha-(1->3)-fucosyltransferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity." [GO_REF:0000059, GOC:TermGenie, PMID:15364955] +synonym: "regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0019222 ! regulation of metabolic process +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +relationship: regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +created_by: rz +creation_date: 2016-10-28T14:39:37Z + +[Term] +id: GO:1905620 +name: negative regulation of alpha-(1->3)-fucosyltransferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity." [GO_REF:0000059, GOC:TermGenie, PMID:15364955] +synonym: "down regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of alpha(1,3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of alpha-(1,3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of alpha-(1->3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of alpha-1,3-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0009892 ! negative regulation of metabolic process +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1905619 ! regulation of alpha-(1->3)-fucosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +relationship: negatively_regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +created_by: rz +creation_date: 2016-10-28T14:39:45Z + +[Term] +id: GO:1905621 +name: positive regulation of alpha-(1->3)-fucosyltransferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity." [GO_REF:0000059, GOC:TermGenie, PMID:15364955] +synonym: "activation of alpha(1,3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of alpha-(1,3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of alpha-(1->3)-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of alpha-1,3-fucosyltransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-(1->3)-fucosyltransferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] +is_a: GO:0009893 ! positive regulation of metabolic process +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1905619 ! regulation of alpha-(1->3)-fucosyltransferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +relationship: positively_regulates GO:0046920 ! alpha-(1->3)-fucosyltransferase activity +created_by: rz +creation_date: 2016-10-28T14:39:52Z + +[Term] +id: GO:1905622 +name: negative regulation of leaf development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leaf development." [GO_REF:0000058, GOC:TermGenie, PMID:11606552] +synonym: "down regulation of leaf development" EXACT [GOC:TermGenie] +synonym: "down-regulation of leaf development" EXACT [GOC:TermGenie] +synonym: "downregulation of leaf development" EXACT [GOC:TermGenie] +synonym: "inhibition of leaf development" NARROW [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000024 ! regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048366 ! leaf development +relationship: negatively_regulates GO:0048366 ! leaf development +created_by: pga +creation_date: 2016-10-28T15:29:57Z + +[Term] +id: GO:1905623 +name: positive regulation of leaf development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leaf development." [GO_REF:0000058, GOC:TermGenie, PMID:11606552] +synonym: "activation of leaf development" NARROW [GOC:TermGenie] +synonym: "up regulation of leaf development" EXACT [GOC:TermGenie] +synonym: "up-regulation of leaf development" EXACT [GOC:TermGenie] +synonym: "upregulation of leaf development" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000024 ! regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048366 ! leaf development +relationship: positively_regulates GO:0048366 ! leaf development +created_by: pga +creation_date: 2016-10-28T15:30:04Z + +[Term] +id: GO:1905624 +name: regulation of L-methionine import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:17556368] +is_a: GO:0010958 ! regulation of amino acid import across plasma membrane +is_a: GO:1904062 ! regulation of cation transmembrane transport +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905544 ! L-methionine import across plasma membrane +relationship: regulates GO:1905544 ! L-methionine import across plasma membrane +created_by: vw +creation_date: 2016-10-29T16:27:29Z + +[Term] +id: GO:1905625 +name: negative regulation of L-methionine import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:17556368] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:1903960 ! negative regulation of anion transmembrane transport +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1905624 ! regulation of L-methionine import across plasma membrane +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905544 ! L-methionine import across plasma membrane +relationship: negatively_regulates GO:1905544 ! L-methionine import across plasma membrane +created_by: vw +creation_date: 2016-10-29T16:27:38Z + +[Term] +id: GO:1905626 +name: positive regulation of L-methionine import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:17556368] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:1903961 ! positive regulation of anion transmembrane transport +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:1905624 ! regulation of L-methionine import across plasma membrane +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905544 ! L-methionine import across plasma membrane +relationship: positively_regulates GO:1905544 ! L-methionine import across plasma membrane +created_by: vw +creation_date: 2016-10-29T16:27:46Z + +[Term] +id: GO:1905627 +name: regulation of serotonin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] +synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0001505 ! regulation of neurotransmitter levels +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042427 ! serotonin biosynthetic process +relationship: regulates GO:0042427 ! serotonin biosynthetic process +created_by: pad +creation_date: 2016-10-31T14:26:20Z + +[Term] +id: GO:1905628 +name: negative regulation of serotonin biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] +synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of serotonin anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of serotonin biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of serotonin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of serotonin formation" NARROW [GOC:TermGenie] +synonym: "inhibition of serotonin synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:1905627 ! regulation of serotonin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042427 ! serotonin biosynthetic process +relationship: negatively_regulates GO:0042427 ! serotonin biosynthetic process +created_by: pad +creation_date: 2016-10-31T14:26:28Z + +[Term] +id: GO:1905629 +name: positive regulation of serotonin biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] +synonym: "activation of serotonin anabolism" NARROW [GOC:TermGenie] +synonym: "activation of serotonin biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of serotonin biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of serotonin formation" NARROW [GOC:TermGenie] +synonym: "activation of serotonin synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie] +synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:1905627 ! regulation of serotonin biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042427 ! serotonin biosynthetic process +relationship: positively_regulates GO:0042427 ! serotonin biosynthetic process +created_by: pad +creation_date: 2016-10-31T14:26:36Z + +[Term] +id: GO:1905630 +name: response to glyceraldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11377826] +is_a: GO:0034284 ! response to monosaccharide +created_by: sl +creation_date: 2016-10-31T16:32:19Z + +[Term] +id: GO:1905631 +name: cellular response to glyceraldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:11377826] +is_a: GO:0071326 ! cellular response to monosaccharide stimulus +is_a: GO:1905630 ! response to glyceraldehyde +created_by: sl +creation_date: 2016-10-31T16:32:27Z + +[Term] +id: GO:1905632 +name: protein localization to euchromatin +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within an euchromatin." [GO_REF:0000087, GOC:TermGenie, PMID:20889714] +synonym: "protein localisation in euchromatin" EXACT [GOC:TermGenie] +synonym: "protein localisation to euchromatin" EXACT [GOC:TermGenie] +synonym: "protein localization in euchromatin" EXACT [GOC:TermGenie] +is_a: GO:0071168 ! protein localization to chromatin +created_by: pga +creation_date: 2016-11-01T16:16:14Z + +[Term] +id: GO:1905633 +name: establishment of protein localization to euchromatin +namespace: biological_process +def: "The directed movement of a protein to a specific location in an euchromatin." [GO_REF:0000087, GOC:TermGenie, PMID:20889714] +synonym: "establishment of protein localisation in euchromatin" EXACT [GOC:TermGenie] +synonym: "establishment of protein localisation to euchromatin" EXACT [GOC:TermGenie] +synonym: "establishment of protein localization in euchromatin" EXACT [GOC:TermGenie] +is_a: GO:0071169 ! establishment of protein localization to chromatin +is_a: GO:1905632 ! protein localization to euchromatin +created_by: pga +creation_date: 2016-11-01T16:16:22Z + +[Term] +id: GO:1905634 +name: regulation of protein localization to chromatin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] +synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071168 ! protein localization to chromatin +relationship: regulates GO:0071168 ! protein localization to chromatin +created_by: pga +creation_date: 2016-11-01T16:33:52Z + +[Term] +id: GO:1905635 +name: FACT complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a FACT complex." [GO_REF:0000079, GOC:TermGenie, PMID:20889714] +synonym: "Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "FACT complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: pga +creation_date: 2016-11-02T15:06:03Z + +[Term] +id: GO:1905636 +name: positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23675531] +synonym: "activation of RNA polymerase II regulatory region sequence-specific DNA binding" NARROW [GOC:TermGenie] +synonym: "up regulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of RNA polymerase II regulatory region sequence-specific DNA binding" EXACT [GOC:TermGenie] +is_a: GO:1903025 ! regulation of RNA polymerase II regulatory region sequence-specific DNA binding +is_a: GO:2000679 ! positive regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +relationship: positively_regulates GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding +created_by: bc +creation_date: 2016-11-03T12:03:07Z + +[Term] +id: GO:1905637 +name: regulation of mitochondrial mRNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:27122350] +is_a: GO:0000960 ! regulation of mitochondrial RNA catabolic process +is_a: GO:0061013 ! regulation of mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000958 ! mitochondrial mRNA catabolic process +relationship: regulates GO:0000958 ! mitochondrial mRNA catabolic process +created_by: tb +creation_date: 2016-11-03T20:23:57Z + +[Term] +id: GO:1905638 +name: negative regulation of mitochondrial mRNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:27122350] +synonym: "down regulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "inhibition of mitochondrial mRNA catabolic process" NARROW [GOC:TermGenie] +is_a: GO:0000961 ! negative regulation of mitochondrial RNA catabolic process +is_a: GO:1902373 ! negative regulation of mRNA catabolic process +is_a: GO:1905637 ! regulation of mitochondrial mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000958 ! mitochondrial mRNA catabolic process +relationship: negatively_regulates GO:0000958 ! mitochondrial mRNA catabolic process +created_by: tb +creation_date: 2016-11-03T20:24:05Z + +[Term] +id: GO:1905639 +name: positive regulation of mitochondrial mRNA catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:27122350] +synonym: "activation of mitochondrial mRNA catabolic process" NARROW [GOC:TermGenie] +synonym: "up regulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of mitochondrial mRNA catabolic process" EXACT [GOC:TermGenie] +is_a: GO:0000962 ! positive regulation of mitochondrial RNA catabolic process +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +is_a: GO:1905637 ! regulation of mitochondrial mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000958 ! mitochondrial mRNA catabolic process +relationship: positively_regulates GO:0000958 ! mitochondrial mRNA catabolic process +created_by: tb +creation_date: 2016-11-03T20:24:13Z + +[Term] +id: GO:1905640 +name: response to acetaldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:27687866] +is_a: GO:0010033 ! response to organic substance +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: mah +creation_date: 2016-11-04T15:07:18Z + +[Term] +id: GO:1905641 +name: cellular response to acetaldehyde +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:27687866] +is_a: GO:0110096 ! cellular response to aldehyde +is_a: GO:1905640 ! response to acetaldehyde +created_by: mah +creation_date: 2016-11-04T15:07:26Z + +[Term] +id: GO:1905642 +name: negative regulation of DNA methylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:27336847] +synonym: "down regulation of DNA methylation" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA methylation" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA methylation" EXACT [GOC:TermGenie] +synonym: "inhibition of DNA methylation" NARROW [GOC:TermGenie] +is_a: GO:0044030 ! regulation of DNA methylation +is_a: GO:0051053 ! negative regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006306 ! DNA methylation +relationship: negatively_regulates GO:0006306 ! DNA methylation +created_by: bc +creation_date: 2016-11-04T16:43:13Z + +[Term] +id: GO:1905643 +name: positive regulation of DNA methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA methylation." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:27336847] +synonym: "activation of DNA methylation" NARROW [GOC:TermGenie] +synonym: "up regulation of DNA methylation" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA methylation" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA methylation" EXACT [GOC:TermGenie] +is_a: GO:0044030 ! regulation of DNA methylation +is_a: GO:0051054 ! positive regulation of DNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006306 ! DNA methylation +relationship: positively_regulates GO:0006306 ! DNA methylation +created_by: bc +creation_date: 2016-11-04T16:43:22Z + +[Term] +id: GO:1905644 +name: regulation of FACT complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of FACT complex assembly." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] +synonym: "regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of FACT complex formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905635 ! FACT complex assembly +relationship: regulates GO:1905635 ! FACT complex assembly +created_by: pga +creation_date: 2016-11-07T09:14:06Z + +[Term] +id: GO:1905645 +name: negative regulation of FACT complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] +synonym: "down regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "inhibition of Facilitates chromatin transcription complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Facilitates chromatin transcription complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of FACT complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of FACT complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of FACT complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1905644 ! regulation of FACT complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905635 ! FACT complex assembly +relationship: negatively_regulates GO:1905635 ! FACT complex assembly +created_by: pga +creation_date: 2016-11-07T09:14:13Z + +[Term] +id: GO:1905646 +name: positive regulation of FACT complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of FACT complex assembly." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] +synonym: "activation of Facilitates chromatin transcription complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Facilitates chromatin transcription complex formation" NARROW [GOC:TermGenie] +synonym: "activation of FACT complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of FACT complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of FACT complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of Facilitates chromatin transcription complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Facilitates chromatin transcription complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of FACT complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of FACT complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1905644 ! regulation of FACT complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905635 ! FACT complex assembly +relationship: positively_regulates GO:1905635 ! FACT complex assembly +created_by: pga +creation_date: 2016-11-07T09:14:21Z + +[Term] +id: GO:1905647 +name: proline import across plasma membrane +namespace: biological_process +alt_id: GO:1902825 +def: "The directed movement of proline from outside of a cell into the cytoplasmic compartment." [GO_REF:0000075, GOC:TermGenie, PMID:24344203] +synonym: "proline import into cell" EXACT [] +is_a: GO:0035524 ! proline transmembrane transport +is_a: GO:0089718 ! amino acid import across plasma membrane +created_by: mah +creation_date: 2014-03-31T13:14:04Z + +[Term] +id: GO:1905648 +name: regulation of shell calcification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of shell calcification." [GO_REF:0000058, GOC:TermGenie, PMID:14648763] +is_a: GO:0070167 ! regulation of biomineral tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031215 ! shell calcification +relationship: regulates GO:0031215 ! shell calcification +created_by: pga +creation_date: 2016-11-08T16:24:36Z + +[Term] +id: GO:1905649 +name: negative regulation of shell calcification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification." [GO_REF:0000058, GOC:TermGenie, PMID:14648763] +synonym: "down regulation of shell calcification" EXACT [GOC:TermGenie] +synonym: "down-regulation of shell calcification" EXACT [GOC:TermGenie] +synonym: "downregulation of shell calcification" EXACT [GOC:TermGenie] +synonym: "inhibition of shell calcification" NARROW [GOC:TermGenie] +is_a: GO:0070168 ! negative regulation of biomineral tissue development +is_a: GO:1905648 ! regulation of shell calcification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031215 ! shell calcification +relationship: negatively_regulates GO:0031215 ! shell calcification +created_by: pga +creation_date: 2016-11-08T16:24:43Z + +[Term] +id: GO:1905650 +name: positive regulation of shell calcification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of shell calcification." [GO_REF:0000058, GOC:TermGenie, PMID:14648763] +synonym: "activation of shell calcification" NARROW [GOC:TermGenie] +synonym: "up regulation of shell calcification" EXACT [GOC:TermGenie] +synonym: "up-regulation of shell calcification" EXACT [GOC:TermGenie] +synonym: "upregulation of shell calcification" EXACT [GOC:TermGenie] +is_a: GO:0070169 ! positive regulation of biomineral tissue development +is_a: GO:1905648 ! regulation of shell calcification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031215 ! shell calcification +relationship: positively_regulates GO:0031215 ! shell calcification +created_by: pga +creation_date: 2016-11-08T16:24:51Z + +[Term] +id: GO:1905651 +name: regulation of artery morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048844 ! artery morphogenesis +relationship: regulates GO:0048844 ! artery morphogenesis +created_by: rph +creation_date: 2016-11-09T12:19:37Z + +[Term] +id: GO:1905652 +name: negative regulation of artery morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of arterial morphogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of arteriogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of artery morphogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie] +is_a: GO:1905651 ! regulation of artery morphogenesis +is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048844 ! artery morphogenesis +relationship: negatively_regulates GO:0048844 ! artery morphogenesis +created_by: rph +creation_date: 2016-11-09T12:19:53Z + +[Term] +id: GO:1905653 +name: positive regulation of artery morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +synonym: "activation of arterial morphogenesis" NARROW [GOC:TermGenie] +synonym: "activation of arteriogenesis" NARROW [GOC:TermGenie] +synonym: "activation of artery morphogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:1904018 ! positive regulation of vasculature development +is_a: GO:1905651 ! regulation of artery morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048844 ! artery morphogenesis +relationship: positively_regulates GO:0048844 ! artery morphogenesis +created_by: rph +creation_date: 2016-11-09T12:20:01Z + +[Term] +id: GO:1905654 +name: regulation of artery smooth muscle contraction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of artery smooth muscle contraction." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +is_a: GO:0003056 ! regulation of vascular smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0014824 ! artery smooth muscle contraction +relationship: regulates GO:0014824 ! artery smooth muscle contraction +created_by: rph +creation_date: 2016-11-09T12:34:46Z + +[Term] +id: GO:1905655 +name: negative regulation of artery smooth muscle contraction +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +synonym: "down regulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "down-regulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "downregulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "inhibition of artery smooth muscle contraction" NARROW [GOC:TermGenie] +is_a: GO:1904694 ! negative regulation of vascular smooth muscle contraction +is_a: GO:1905654 ! regulation of artery smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0014824 ! artery smooth muscle contraction +relationship: negatively_regulates GO:0014824 ! artery smooth muscle contraction +created_by: rph +creation_date: 2016-11-09T12:34:53Z + +[Term] +id: GO:1905656 +name: positive regulation of artery smooth muscle contraction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] +synonym: "activation of artery smooth muscle contraction" NARROW [GOC:TermGenie] +synonym: "up regulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "up-regulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +synonym: "upregulation of artery smooth muscle contraction" EXACT [GOC:TermGenie] +is_a: GO:1904695 ! positive regulation of vascular smooth muscle contraction +is_a: GO:1905654 ! regulation of artery smooth muscle contraction +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0014824 ! artery smooth muscle contraction +relationship: positively_regulates GO:0014824 ! artery smooth muscle contraction +created_by: rph +creation_date: 2016-11-09T12:35:01Z + +[Term] +id: GO:1905660 +name: mitotic checkpoint complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex." [GO_REF:0000079, GOC:TermGenie, PMID:26882497] +synonym: "MCC assembly" EXACT [GOC:TermGenie] +synonym: "MCC formation" EXACT [GOC:TermGenie] +synonym: "mitotic checkpoint complex formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: mah +creation_date: 2016-11-09T14:17:41Z + +[Term] +id: GO:1905661 +name: regulation of telomerase RNA reverse transcriptase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22633954] +synonym: "regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +is_a: GO:0051972 ! regulation of telomerase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +relationship: regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +created_by: nc +creation_date: 2016-11-09T16:55:20Z + +[Term] +id: GO:1905662 +name: negative regulation of telomerase RNA reverse transcriptase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22633954] +synonym: "down regulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "downregulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "inhibition of telomerase RNA reverse transcriptase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of telomerase, catalyst" NARROW [GOC:TermGenie] +synonym: "negative regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +is_a: GO:0051974 ! negative regulation of telomerase activity +is_a: GO:1905661 ! regulation of telomerase RNA reverse transcriptase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +relationship: negatively_regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +created_by: nc +creation_date: 2016-11-09T16:55:28Z + +[Term] +id: GO:1905663 +name: positive regulation of telomerase RNA reverse transcriptase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:22633954] +synonym: "activation of telomerase RNA reverse transcriptase activity" NARROW [GOC:TermGenie] +synonym: "activation of telomerase, catalyst" NARROW [GOC:TermGenie] +synonym: "positive regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "up regulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomerase, catalyst" EXACT [GOC:TermGenie] +synonym: "upregulation of telomerase RNA reverse transcriptase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of telomerase, catalyst" EXACT [GOC:TermGenie] +is_a: GO:0051973 ! positive regulation of telomerase activity +is_a: GO:1905661 ! regulation of telomerase RNA reverse transcriptase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +relationship: positively_regulates GO:0003721 ! telomerase RNA reverse transcriptase activity +created_by: nc +creation_date: 2016-11-09T16:55:35Z + +[Term] +id: GO:1905664 +name: regulation of calcium ion import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17640527] +comment: An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay). +is_a: GO:0010522 ! regulation of calcium ion transport into cytosol +is_a: GO:0090279 ! regulation of calcium ion import +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098703 ! calcium ion import across plasma membrane +relationship: regulates GO:0098703 ! calcium ion import across plasma membrane +created_by: bhm +creation_date: 2016-11-11T09:26:06Z + +[Term] +id: GO:1905665 +name: positive regulation of calcium ion import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17640527] +comment: An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay). +synonym: "activation of calcium ion import across plasma membrane" NARROW [GOC:TermGenie] +synonym: "up regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:0010524 ! positive regulation of calcium ion transport into cytosol +is_a: GO:0090280 ! positive regulation of calcium ion import +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +is_a: GO:1905664 ! regulation of calcium ion import across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098703 ! calcium ion import across plasma membrane +relationship: positively_regulates GO:0098703 ! calcium ion import across plasma membrane +created_by: bhm +creation_date: 2016-11-11T09:26:23Z + +[Term] +id: GO:1905666 +name: regulation of protein localization to endosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to endosome." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:22732145] +synonym: "regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in endosome" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036010 ! protein localization to endosome +relationship: regulates GO:0036010 ! protein localization to endosome +created_by: bc +creation_date: 2016-11-11T11:19:01Z + +[Term] +id: GO:1905667 +name: negative regulation of protein localization to endosome +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:22732145] +synonym: "down regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to endosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to endosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to endosome" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in endosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in endosome" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to endosome" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in endosome" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905666 ! regulation of protein localization to endosome +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036010 ! protein localization to endosome +relationship: negatively_regulates GO:0036010 ! protein localization to endosome +created_by: bc +creation_date: 2016-11-11T11:19:09Z + +[Term] +id: GO:1905668 +name: positive regulation of protein localization to endosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to endosome." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:22732145] +synonym: "activation of protein localisation in endosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in endosome" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to endosome" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in endosome" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to endosome" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905666 ! regulation of protein localization to endosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036010 ! protein localization to endosome +relationship: positively_regulates GO:0036010 ! protein localization to endosome +created_by: bc +creation_date: 2016-11-11T11:19:17Z + +[Term] +id: GO:1905669 +name: TORC1 complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, PMID:21952218] +synonym: "dTOR/dRaptor complex assembly" NARROW [GOC:TermGenie] +synonym: "dTOR/dRaptor complex formation" NARROW [GOC:TermGenie] +synonym: "dTORC1 assembly" NARROW [GOC:TermGenie] +synonym: "dTORC1 formation" NARROW [GOC:TermGenie] +synonym: "mTORC1 assembly" NARROW [GOC:TermGenie] +synonym: "mTORC1 formation" NARROW [GOC:TermGenie] +synonym: "nutrient sensitive complex assembly" EXACT [GOC:TermGenie] +synonym: "nutrient sensitive complex formation" EXACT [GOC:TermGenie] +synonym: "rapamycin and nutrient-sensitive TOR complex assembly" EXACT [GOC:TermGenie] +synonym: "rapamycin and nutrient-sensitive TOR complex formation" EXACT [GOC:TermGenie] +synonym: "TOR complex 1 assembly" EXACT [GOC:TermGenie] +synonym: "TOR complex 1 formation" EXACT [GOC:TermGenie] +synonym: "TORC 1 complex assembly" EXACT [GOC:TermGenie] +synonym: "TORC 1 complex formation" EXACT [GOC:TermGenie] +synonym: "TORC1 assembly" EXACT [GOC:TermGenie] +synonym: "TORC1 complex formation" EXACT [GOC:TermGenie] +synonym: "TORC1 formation" EXACT [GOC:TermGenie] +is_a: GO:0065003 ! protein-containing complex assembly +created_by: kmv +creation_date: 2016-11-11T21:03:27Z + +[Term] +id: GO:1905670 +name: TORC2 complex disassembly +namespace: biological_process +def: "The disaggregation of a TORC2 complex into its constituent components." [GO_REF:0000079, GOC:kmv, GOC:TermGenie, PMID:21952218] +synonym: "mTORC2 disassembly" NARROW [GOC:TermGenie] +synonym: "rapamycin and nutrient-insensitive TOR complex disassembly" EXACT [GOC:TermGenie] +synonym: "TOR complex 2 disassembly" EXACT [GOC:TermGenie] +synonym: "TORC 2 complex disassembly" EXACT [GOC:TermGenie] +synonym: "TORC2 disassembly" EXACT [GOC:TermGenie] +is_a: GO:0032984 ! protein-containing complex disassembly +created_by: kmv +creation_date: 2016-11-11T21:03:37Z + +[Term] +id: GO:1905671 +name: regulation of lysosome organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lysosome organization." [GO_REF:0000058, GOC:TermGenie, PMID:25561470] +synonym: "regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0044088 ! regulation of vacuole organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007040 ! lysosome organization +relationship: regulates GO:0007040 ! lysosome organization +created_by: sl +creation_date: 2016-11-11T22:01:04Z + +[Term] +id: GO:1905672 +name: negative regulation of lysosome organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization." [GO_REF:0000058, GOC:TermGenie, PMID:25561470] +synonym: "down regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "down regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "downregulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of lysosome organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosome organization" NARROW [GOC:TermGenie] +synonym: "inhibition of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1905671 ! regulation of lysosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007040 ! lysosome organization +relationship: negatively_regulates GO:0007040 ! lysosome organization +created_by: sl +creation_date: 2016-11-11T22:01:12Z + +[Term] +id: GO:1905673 +name: positive regulation of lysosome organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lysosome organization." [GO_REF:0000058, GOC:TermGenie, PMID:25561470] +synonym: "activation of lysosome organisation" NARROW [GOC:TermGenie] +synonym: "activation of lysosome organization" NARROW [GOC:TermGenie] +synonym: "activation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "positive regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "up regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "up-regulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "upregulation of lysosome organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosome organization" EXACT [GOC:TermGenie] +synonym: "upregulation of lysosome organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0044090 ! positive regulation of vacuole organization +is_a: GO:1905671 ! regulation of lysosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007040 ! lysosome organization +relationship: positively_regulates GO:0007040 ! lysosome organization +created_by: sl +creation_date: 2016-11-11T22:01:20Z + +[Term] +id: GO:1905674 +name: regulation of adaptive immune memory response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adaptive immune memory response." [GO_REF:0000058, GOC:TermGenie, PMID:26831526] +is_a: GO:0002819 ! regulation of adaptive immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090716 ! adaptive immune memory response +relationship: regulates GO:0090716 ! adaptive immune memory response +created_by: tb +creation_date: 2016-11-11T22:24:33Z + +[Term] +id: GO:1905675 +name: negative regulation of adaptive immune memory response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response." [GO_REF:0000058, GOC:TermGenie, PMID:26831526] +synonym: "down regulation of adaptive immune memory response" EXACT [GOC:TermGenie] +synonym: "down-regulation of adaptive immune memory response" EXACT [GOC:TermGenie] +synonym: "downregulation of adaptive immune memory response" EXACT [GOC:TermGenie] +synonym: "inhibition of adaptive immune memory response" NARROW [GOC:TermGenie] +is_a: GO:0002820 ! negative regulation of adaptive immune response +is_a: GO:1905674 ! regulation of adaptive immune memory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090716 ! adaptive immune memory response +relationship: negatively_regulates GO:0090716 ! adaptive immune memory response +created_by: tb +creation_date: 2016-11-11T22:24:41Z + +[Term] +id: GO:1905676 +name: positive regulation of adaptive immune memory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adaptive immune memory response." [GO_REF:0000058, GOC:TermGenie, PMID:26831526] +synonym: "activation of adaptive immune memory response" NARROW [GOC:TermGenie] +synonym: "up regulation of adaptive immune memory response" EXACT [GOC:TermGenie] +synonym: "up-regulation of adaptive immune memory response" EXACT [GOC:TermGenie] +synonym: "upregulation of adaptive immune memory response" EXACT [GOC:TermGenie] +is_a: GO:0002821 ! positive regulation of adaptive immune response +is_a: GO:1905674 ! regulation of adaptive immune memory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090716 ! adaptive immune memory response +relationship: positively_regulates GO:0090716 ! adaptive immune memory response +created_by: tb +creation_date: 2016-11-11T22:24:49Z + +[Term] +id: GO:1905677 +name: regulation of adaptive immune effector response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adaptive immune effector response." [GO_REF:0000058, GOC:TermGenie, ISBN:9781405196833] +is_a: GO:0002819 ! regulation of adaptive immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090718 ! adaptive immune effector response +relationship: regulates GO:0090718 ! adaptive immune effector response +created_by: tb +creation_date: 2016-11-11T22:24:57Z + +[Term] +id: GO:1905678 +name: negative regulation of adaptive immune effector response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response." [GO_REF:0000058, GOC:TermGenie, ISBN:9781405196833] +synonym: "down regulation of adaptive immune effector response" EXACT [GOC:TermGenie] +synonym: "down-regulation of adaptive immune effector response" EXACT [GOC:TermGenie] +synonym: "downregulation of adaptive immune effector response" EXACT [GOC:TermGenie] +synonym: "inhibition of adaptive immune effector response" NARROW [GOC:TermGenie] +is_a: GO:0002820 ! negative regulation of adaptive immune response +is_a: GO:1905677 ! regulation of adaptive immune effector response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090718 ! adaptive immune effector response +relationship: negatively_regulates GO:0090718 ! adaptive immune effector response +created_by: tb +creation_date: 2016-11-11T22:25:05Z + +[Term] +id: GO:1905679 +name: positive regulation of adaptive immune effector response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of adaptive immune effector response." [GO_REF:0000058, GOC:TermGenie, ISBN:9781405196833] +synonym: "activation of adaptive immune effector response" NARROW [GOC:TermGenie] +synonym: "up regulation of adaptive immune effector response" EXACT [GOC:TermGenie] +synonym: "up-regulation of adaptive immune effector response" EXACT [GOC:TermGenie] +synonym: "upregulation of adaptive immune effector response" EXACT [GOC:TermGenie] +is_a: GO:0002821 ! positive regulation of adaptive immune response +is_a: GO:1905677 ! regulation of adaptive immune effector response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090718 ! adaptive immune effector response +relationship: positively_regulates GO:0090718 ! adaptive immune effector response +created_by: tb +creation_date: 2016-11-11T22:25:13Z + +[Term] +id: GO:1905680 +name: regulation of innate immunity memory response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of innate immunity memory response." [GO_REF:0000058, GOC:TermGenie] +is_a: GO:0045088 ! regulation of innate immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090714 ! innate immunity memory response +relationship: regulates GO:0090714 ! innate immunity memory response +created_by: tb +creation_date: 2016-11-11T22:25:21Z + +[Term] +id: GO:1905681 +name: negative regulation of innate immunity memory response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response." [GO_REF:0000058, GOC:TermGenie] +synonym: "down regulation of innate immunity memory response" EXACT [GOC:TermGenie] +synonym: "down-regulation of innate immunity memory response" EXACT [GOC:TermGenie] +synonym: "downregulation of innate immunity memory response" EXACT [GOC:TermGenie] +synonym: "inhibition of innate immunity memory response" NARROW [GOC:TermGenie] +is_a: GO:0045824 ! negative regulation of innate immune response +is_a: GO:1905680 ! regulation of innate immunity memory response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090714 ! innate immunity memory response +relationship: negatively_regulates GO:0090714 ! innate immunity memory response +created_by: tb +creation_date: 2016-11-11T22:25:29Z + +[Term] +id: GO:1905682 +name: positive regulation of innate immunity memory response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of innate immunity memory response." [GO_REF:0000058, GOC:TermGenie] +synonym: "activation of innate immunity memory response" NARROW [GOC:TermGenie] +synonym: "up regulation of innate immunity memory response" EXACT [GOC:TermGenie] +synonym: "up-regulation of innate immunity memory response" EXACT [GOC:TermGenie] +synonym: "upregulation of innate immunity memory response" EXACT [GOC:TermGenie] +is_a: GO:0045089 ! positive regulation of innate immune response +is_a: GO:1905680 ! regulation of innate immunity memory response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090714 ! innate immunity memory response +relationship: positively_regulates GO:0090714 ! innate immunity memory response +created_by: tb +creation_date: 2016-11-11T22:25:36Z + +[Term] +id: GO:1905683 +name: peroxisome disassembly +namespace: biological_process +def: "The disaggregation of a peroxisome into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] +synonym: "peroxisomal disassembly" RELATED [GOC:TermGenie] +is_a: GO:0007031 ! peroxisome organization +is_a: GO:1903008 ! organelle disassembly +created_by: pr +creation_date: 2016-11-14T10:09:15Z + +[Term] +id: GO:1905684 +name: regulation of plasma membrane repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plasma membrane repair." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:22940583] +is_a: GO:0061041 ! regulation of wound healing +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001778 ! plasma membrane repair +relationship: regulates GO:0001778 ! plasma membrane repair +created_by: bhm +creation_date: 2016-11-14T10:30:31Z + +[Term] +id: GO:1905685 +name: negative regulation of plasma membrane repair +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:22940583] +synonym: "down regulation of plasma membrane repair" EXACT [GOC:TermGenie] +synonym: "down-regulation of plasma membrane repair" EXACT [GOC:TermGenie] +synonym: "downregulation of plasma membrane repair" EXACT [GOC:TermGenie] +synonym: "inhibition of plasma membrane repair" NARROW [GOC:TermGenie] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:0061045 ! negative regulation of wound healing +is_a: GO:1905684 ! regulation of plasma membrane repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001778 ! plasma membrane repair +relationship: negatively_regulates GO:0001778 ! plasma membrane repair +created_by: bhm +creation_date: 2016-11-14T10:30:38Z + +[Term] +id: GO:1905686 +name: positive regulation of plasma membrane repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plasma membrane repair." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:22940583] +synonym: "activation of plasma membrane repair" NARROW [GOC:TermGenie] +synonym: "up regulation of plasma membrane repair" EXACT [GOC:TermGenie] +synonym: "up-regulation of plasma membrane repair" EXACT [GOC:TermGenie] +synonym: "upregulation of plasma membrane repair" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:0090303 ! positive regulation of wound healing +is_a: GO:1905684 ! regulation of plasma membrane repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001778 ! plasma membrane repair +relationship: positively_regulates GO:0001778 ! plasma membrane repair +created_by: bhm +creation_date: 2016-11-14T10:30:46Z + +[Term] +id: GO:1905687 +name: regulation of diacylglycerol kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23091060] +synonym: "regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0043549 ! regulation of kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004143 ! diacylglycerol kinase activity +relationship: regulates GO:0004143 ! diacylglycerol kinase activity +created_by: bc +creation_date: 2016-11-14T12:26:11Z + +[Term] +id: GO:1905688 +name: negative regulation of diacylglycerol kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23091060] +synonym: "down regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "down regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "down regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "down-regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "downregulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "downregulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of 1,2-diacylglycerol kinase (phosphorylating)" NARROW [GOC:TermGenie] +synonym: "inhibition of 1,2-diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of arachidonoyl-specific diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DG kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DGK activity" NARROW [GOC:TermGenie] +synonym: "inhibition of diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of diglyceride kinase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of sn-1,2-diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "negative regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "negative regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0033673 ! negative regulation of kinase activity +is_a: GO:1905687 ! regulation of diacylglycerol kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004143 ! diacylglycerol kinase activity +relationship: negatively_regulates GO:0004143 ! diacylglycerol kinase activity +created_by: bc +creation_date: 2016-11-14T12:26:18Z + +[Term] +id: GO:1905689 +name: positive regulation of diacylglycerol kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23091060] +synonym: "activation of 1,2-diacylglycerol kinase (phosphorylating)" NARROW [GOC:TermGenie] +synonym: "activation of 1,2-diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of arachidonoyl-specific diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "activation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of DG kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of DGK activity" NARROW [GOC:TermGenie] +synonym: "activation of diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of diglyceride kinase activity" NARROW [GOC:TermGenie] +synonym: "activation of sn-1,2-diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "positive regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "up regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "up-regulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of 1,2-diacylglycerol kinase (phosphorylating)" EXACT [GOC:TermGenie] +synonym: "upregulation of 1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of arachidonoyl-specific diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of ATP:diacylglycerol phosphotransferase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of CTP:diacylglycerol kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of DG kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DGK activity" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of diacylglycerol:ATP kinase activity" NARROW [GOC:TermGenie] +synonym: "upregulation of diglyceride kinase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of sn-1,2-diacylglycerol kinase activity" EXACT [GOC:TermGenie] +is_a: GO:0033674 ! positive regulation of kinase activity +is_a: GO:1905687 ! regulation of diacylglycerol kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004143 ! diacylglycerol kinase activity +relationship: positively_regulates GO:0004143 ! diacylglycerol kinase activity +created_by: bc +creation_date: 2016-11-14T12:26:26Z + +[Term] +id: GO:1905690 +name: nucleus disassembly +namespace: biological_process +def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] +synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie] +is_a: GO:0006997 ! nucleus organization +is_a: GO:1903008 ! organelle disassembly +created_by: pr +creation_date: 2016-11-14T13:38:57Z + +[Term] +id: GO:1905691 +name: lipid droplet disassembly +namespace: biological_process +def: "The disaggregation of a lipid particle into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] +synonym: "adiposome disassembly" EXACT [GOC:TermGenie] +synonym: "lipid body disassembly" EXACT [GOC:TermGenie] +synonym: "lipid droplet reserve breakdown" EXACT [PMID:30003614] +synonym: "lipid particle disassembly" EXACT [GOC:TermGenie] +is_a: GO:0034389 ! lipid droplet organization +is_a: GO:1903008 ! organelle disassembly +created_by: pr +creation_date: 2016-11-14T13:39:06Z + +[Term] +id: GO:1905692 +name: endoplasmic reticulum disassembly +namespace: biological_process +def: "The disaggregation of an endoplasmic reticulum into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] +synonym: "ER disassembly" EXACT [GOC:TermGenie] +is_a: GO:0007029 ! endoplasmic reticulum organization +is_a: GO:1903008 ! organelle disassembly +created_by: pr +creation_date: 2016-11-14T13:39:14Z + +[Term] +id: GO:1905693 +name: regulation of phosphatidic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23767959] +synonym: "regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006654 ! phosphatidic acid biosynthetic process +relationship: regulates GO:0006654 ! phosphatidic acid biosynthetic process +created_by: bc +creation_date: 2016-11-14T14:48:09Z + +[Term] +id: GO:1905694 +name: negative regulation of phosphatidic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23767959] +synonym: "down regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid formation" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidic acid synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +is_a: GO:1905693 ! regulation of phosphatidic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006654 ! phosphatidic acid biosynthetic process +relationship: negatively_regulates GO:0006654 ! phosphatidic acid biosynthetic process +created_by: bc +creation_date: 2016-11-14T14:48:16Z + +[Term] +id: GO:1905695 +name: positive regulation of phosphatidic acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:23767959] +synonym: "activation of phosphatidic acid anabolism" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidic acid biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidic acid biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidic acid formation" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidic acid synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid formation" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidic acid synthesis" EXACT [GOC:TermGenie] +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +is_a: GO:1905693 ! regulation of phosphatidic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006654 ! phosphatidic acid biosynthetic process +relationship: positively_regulates GO:0006654 ! phosphatidic acid biosynthetic process +created_by: bc +creation_date: 2016-11-14T14:48:24Z + +[Term] +id: GO:1905696 +name: regulation of polysome binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of polysome binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "regulation of polyribosome binding" EXACT [GOC:TermGenie] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905538 ! polysome binding +relationship: regulates GO:1905538 ! polysome binding +created_by: bc +creation_date: 2016-11-14T23:26:22Z + +[Term] +id: GO:1905697 +name: negative regulation of polysome binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "down regulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "down regulation of polysome binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of polysome binding" EXACT [GOC:TermGenie] +synonym: "downregulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "downregulation of polysome binding" EXACT [GOC:TermGenie] +synonym: "inhibition of polyribosome binding" NARROW [GOC:TermGenie] +synonym: "inhibition of polysome binding" NARROW [GOC:TermGenie] +synonym: "negative regulation of polyribosome binding" EXACT [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1905696 ! regulation of polysome binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905538 ! polysome binding +relationship: negatively_regulates GO:1905538 ! polysome binding +created_by: bc +creation_date: 2016-11-14T23:26:29Z + +[Term] +id: GO:1905698 +name: positive regulation of polysome binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of polysome binding." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:18426977] +synonym: "activation of polyribosome binding" NARROW [GOC:TermGenie] +synonym: "activation of polysome binding" NARROW [GOC:TermGenie] +synonym: "positive regulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "up regulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "up regulation of polysome binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of polysome binding" EXACT [GOC:TermGenie] +synonym: "upregulation of polyribosome binding" EXACT [GOC:TermGenie] +synonym: "upregulation of polysome binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1905696 ! regulation of polysome binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905538 ! polysome binding +relationship: positively_regulates GO:1905538 ! polysome binding +created_by: bc +creation_date: 2016-11-14T23:26:37Z + +[Term] +id: GO:1905699 +name: regulation of xenobiotic detoxification by transmembrane export across the plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of drug transmembrane export." [GO_REF:0000058, GOC:TermGenie, PMID:15198509] +synonym: "regulation of drug transmembrane export" NARROW [] +synonym: "regulation of xenobiotic transmembrane export" NARROW [] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +relationship: regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17083 xsd:anyURI +created_by: sl +creation_date: 2016-11-15T16:46:28Z + +[Term] +id: GO:1905700 +name: negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of drug transmembrane export." [GO_REF:0000058, GOC:TermGenie, PMID:15198509] +synonym: "down regulation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "down-regulation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "downregulation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "inhibition of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "negative regulation of drug transmembrane export" NARROW [] +synonym: "negative regulation of xenobiotic transmembrane export" NARROW [] +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905699 ! regulation of xenobiotic detoxification by transmembrane export across the plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +relationship: negatively_regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17083 xsd:anyURI +created_by: sl +creation_date: 2016-11-15T16:46:36Z + +[Term] +id: GO:1905701 +name: positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of drug transmembrane export." [GO_REF:0000058, GOC:TermGenie, PMID:15198509] +synonym: "activation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "positive regulation of drug transmembrane export" NARROW [] +synonym: "positive regulation of xenobiotic transmembrane export" NARROW [] +synonym: "up regulation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "up-regulation of drug transmembrane export" NARROW [GOC:TermGenie] +synonym: "upregulation of drug transmembrane export" NARROW [GOC:TermGenie] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905699 ! regulation of xenobiotic detoxification by transmembrane export across the plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +relationship: positively_regulates GO:1990961 ! xenobiotic detoxification by transmembrane export across the plasma membrane +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17083 xsd:anyURI +created_by: sl +creation_date: 2016-11-15T16:46:44Z + +[Term] +id: GO:1905702 +name: regulation of inhibitory synapse assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inhibitory synapse assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051963 ! regulation of synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904862 ! inhibitory synapse assembly +relationship: regulates GO:1904862 ! inhibitory synapse assembly +created_by: tb +creation_date: 2016-11-16T18:55:32Z + +[Term] +id: GO:1905703 +name: negative regulation of inhibitory synapse assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "down regulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "inhibition of inhibitory synapse assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of inhibitory synapse formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051964 ! negative regulation of synapse assembly +is_a: GO:1905702 ! regulation of inhibitory synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904862 ! inhibitory synapse assembly +relationship: negatively_regulates GO:1904862 ! inhibitory synapse assembly +created_by: tb +creation_date: 2016-11-16T18:55:40Z + +[Term] +id: GO:1905704 +name: positive regulation of inhibitory synapse assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "activation of inhibitory synapse assembly" NARROW [GOC:TermGenie] +synonym: "activation of inhibitory synapse formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibitory synapse assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of inhibitory synapse formation" EXACT [GOC:TermGenie] +is_a: GO:0051965 ! positive regulation of synapse assembly +is_a: GO:1905702 ! regulation of inhibitory synapse assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904862 ! inhibitory synapse assembly +relationship: positively_regulates GO:1904862 ! inhibitory synapse assembly +created_by: tb +creation_date: 2016-11-16T18:55:49Z + +[Term] +id: GO:1905705 +name: cellular response to paclitaxel +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:18472094] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901555 ! response to paclitaxel +created_by: sl +creation_date: 2016-11-16T21:40:32Z + +[Term] +id: GO:1905706 +name: regulation of mitochondrial ATP synthesis coupled proton transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport." [GO_REF:0000058, GOC:TermGenie, PMID:12809520, PMID:15294286] +is_a: GO:0002082 ! regulation of oxidative phosphorylation +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:2001169 ! regulation of ATP biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042776 ! mitochondrial ATP synthesis coupled proton transport +relationship: regulates GO:0042776 ! mitochondrial ATP synthesis coupled proton transport +created_by: vw +creation_date: 2016-11-17T14:07:33Z + +[Term] +id: GO:1905707 +name: negative regulation of mitochondrial ATP synthesis coupled proton transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport." [GO_REF:0000058, GOC:TermGenie, PMID:12809520, PMID:15294286] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0090324 ! negative regulation of oxidative phosphorylation +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:1905706 ! regulation of mitochondrial ATP synthesis coupled proton transport +is_a: GO:2001170 ! negative regulation of ATP biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042776 ! mitochondrial ATP synthesis coupled proton transport +relationship: negatively_regulates GO:0042776 ! mitochondrial ATP synthesis coupled proton transport +created_by: vw +creation_date: 2016-11-17T14:07:40Z + +[Term] +id: GO:1905708 +name: regulation of cell morphogenesis involved in conjugation with cellular fusion +namespace: biological_process +def: "Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion." [GO_REF:0000058, GOC:TermGenie, PMID:23200991] +synonym: "regulation of shmoo orientation" NARROW [GOC:TermGenie] +synonym: "regulation of shmooing" NARROW [GOC:TermGenie] +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:0031137 ! regulation of conjugation with cellular fusion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000753 ! cell morphogenesis involved in conjugation with cellular fusion +relationship: regulates GO:0000753 ! cell morphogenesis involved in conjugation with cellular fusion +created_by: mah +creation_date: 2016-11-18T11:33:54Z + +[Term] +id: GO:1905709 +name: negative regulation of membrane permeability +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane." [PMID:27482894] +is_a: GO:0090559 ! regulation of membrane permeability +created_by: hbye +creation_date: 2016-11-18T13:10:42Z + +[Term] +id: GO:1905710 +name: positive regulation of membrane permeability +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane." [PMID:27482894] +is_a: GO:0090559 ! regulation of membrane permeability +created_by: hbye +creation_date: 2016-11-18T13:10:53Z + +[Term] +id: GO:1905711 +name: response to phosphatidylethanolamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1657995] +synonym: "response to PE" EXACT [] +synonym: "response to phosphatidyl(amino)ethanols" EXACT [] +synonym: "response to phosphatidylethanolamines" EXACT [] +synonym: "response to PtdEtn" EXACT [] +is_a: GO:0033993 ! response to lipid +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2016-11-21T19:55:32Z + +[Term] +id: GO:1905712 +name: cellular response to phosphatidylethanolamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1657995] +synonym: "cellular response to PE" EXACT [] +synonym: "cellular response to phosphatidyl(amino)ethanols" EXACT [] +synonym: "cellular response to phosphatidylethanolamines" EXACT [] +synonym: "cellular response to PtdEtn" EXACT [] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905711 ! response to phosphatidylethanolamine +created_by: sl +creation_date: 2016-11-21T19:55:40Z + +[Term] +id: GO:1905713 +name: obsolete mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: biological_process +def: "OBSOLETE. Any mitochondrial calcium uptake that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium levels" EXACT [GOC:TermGenie] +synonym: "mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium levels" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2016-11-23T15:55:53Z + +[Term] +id: GO:1905714 +name: obsolete mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium ion concentration +namespace: biological_process +def: "OBSOLETE. Any mitochondrial calcium release that is involved in regulation of presynaptic cytosolic calcium ion concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration" EXACT [GOC:TermGenie] +synonym: "calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium levels" EXACT [GOC:TermGenie] +synonym: "mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium levels" EXACT [GOC:TermGenie] +is_obsolete: true +created_by: dos +creation_date: 2016-11-23T15:56:01Z + +[Term] +id: GO:1905715 +name: regulation of cornification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cornification." [GO_REF:0000058, GOC:TermGenie, PMID:26014679] +is_a: GO:0043067 ! regulation of programmed cell death +is_a: GO:0045616 ! regulation of keratinocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070268 ! cornification +relationship: regulates GO:0070268 ! cornification +created_by: pga +creation_date: 2016-11-24T13:52:55Z + +[Term] +id: GO:1905716 +name: negative regulation of cornification +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cornification." [GO_REF:0000058, GOC:TermGenie, PMID:26014679] +synonym: "down regulation of cornification" EXACT [GOC:TermGenie] +synonym: "down-regulation of cornification" EXACT [GOC:TermGenie] +synonym: "downregulation of cornification" EXACT [GOC:TermGenie] +synonym: "inhibition of cornification" NARROW [GOC:TermGenie] +is_a: GO:0043069 ! negative regulation of programmed cell death +is_a: GO:0045617 ! negative regulation of keratinocyte differentiation +is_a: GO:1905715 ! regulation of cornification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070268 ! cornification +relationship: negatively_regulates GO:0070268 ! cornification +created_by: pga +creation_date: 2016-11-24T13:53:03Z + +[Term] +id: GO:1905717 +name: positive regulation of cornification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cornification." [GO_REF:0000058, GOC:TermGenie, PMID:26014679] +synonym: "activation of cornification" NARROW [GOC:TermGenie] +synonym: "up regulation of cornification" EXACT [GOC:TermGenie] +synonym: "up-regulation of cornification" EXACT [GOC:TermGenie] +synonym: "upregulation of cornification" EXACT [GOC:TermGenie] +is_a: GO:0043068 ! positive regulation of programmed cell death +is_a: GO:0045618 ! positive regulation of keratinocyte differentiation +is_a: GO:1905715 ! regulation of cornification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070268 ! cornification +relationship: positively_regulates GO:0070268 ! cornification +created_by: pga +creation_date: 2016-11-24T13:53:21Z + +[Term] +id: GO:1905718 +name: obsolete mitotic spindle astral microtubule end +namespace: cellular_component +def: "OBSOLETE. Any microtubule end that is part of a mitotic spindle astral microtubule." [GO_REF:0000064, GOC:TermGenie, PMID:11007487] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "mitotic spindle astral microtubule tip" EXACT [] +is_obsolete: true +created_by: vw +creation_date: 2016-11-24T14:30:11Z + +[Term] +id: GO:1905719 +name: protein localization to perinuclear region of cytoplasm +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] +synonym: "protein localisation in perinuclear region of cytoplasm" EXACT [GOC:TermGenie] +synonym: "protein localisation to perinuclear region of cytoplasm" EXACT [GOC:TermGenie] +synonym: "protein localization in perinuclear region of cytoplasm" EXACT [GOC:TermGenie] +synonym: "protein localization to perinuclear cytoplasm" EXACT [] +is_a: GO:0008104 ! protein localization +created_by: mah +creation_date: 2016-11-24T16:51:55Z + +[Term] +id: GO:1905720 +name: cytoplasmic microtubule bundle +namespace: cellular_component +def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291] +synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie] +synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie] +is_a: GO:0097427 ! microtubule bundle +intersection_of: GO:0097427 ! microtubule bundle +intersection_of: part_of GO:0005737 ! cytoplasm +relationship: part_of GO:0005737 ! cytoplasm +created_by: mah +creation_date: 2016-11-24T16:52:02Z + +[Term] +id: GO:1905721 +name: mitotic spindle astral microtubule end +namespace: cellular_component +def: "Any microtubule end that is part of a mitotic spindle astral microtubule." [GO_REF:0000064, GOC:TermGenie, PMID:11007487] +synonym: "mitotic spindle astral microtubule tip" EXACT [] +is_a: GO:1990752 ! microtubule end +intersection_of: GO:1990752 ! microtubule end +intersection_of: part_of GO:0061673 ! mitotic spindle astral microtubule +relationship: part_of GO:0061673 ! mitotic spindle astral microtubule +created_by: vw +creation_date: 2016-11-25T12:26:18Z + +[Term] +id: GO:1905722 +name: regulation of trypanothione biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:18949025] +synonym: "regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019342 ! trypanothione biosynthetic process +relationship: regulates GO:0019342 ! trypanothione biosynthetic process +created_by: rz +creation_date: 2016-11-25T14:44:34Z + +[Term] +id: GO:1905723 +name: negative regulation of trypanothione biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:18949025] +synonym: "down regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "down regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "downregulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of trypanothione anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of trypanothione biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of trypanothione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of trypanothione formation" NARROW [GOC:TermGenie] +synonym: "inhibition of trypanothione synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:1905722 ! regulation of trypanothione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019342 ! trypanothione biosynthetic process +relationship: negatively_regulates GO:0019342 ! trypanothione biosynthetic process +created_by: rz +creation_date: 2016-11-25T14:44:42Z + +[Term] +id: GO:1905724 +name: positive regulation of trypanothione biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process." [GO_REF:0000058, GOC:TermGenie, PMID:18949025] +synonym: "activation of trypanothione anabolism" NARROW [GOC:TermGenie] +synonym: "activation of trypanothione biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of trypanothione biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of trypanothione formation" NARROW [GOC:TermGenie] +synonym: "activation of trypanothione synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "up regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of trypanothione synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of trypanothione anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of trypanothione biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of trypanothione biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of trypanothione formation" EXACT [GOC:TermGenie] +synonym: "upregulation of trypanothione synthesis" EXACT [GOC:TermGenie] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:0051176 ! positive regulation of sulfur metabolic process +is_a: GO:1905722 ! regulation of trypanothione biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019342 ! trypanothione biosynthetic process +relationship: positively_regulates GO:0019342 ! trypanothione biosynthetic process +created_by: rz +creation_date: 2016-11-25T14:44:50Z + +[Term] +id: GO:1905725 +name: protein localization to microtubule end +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at a microtubule end." [GO_REF:0000087, GOC:TermGenie, PMID:12034771] +synonym: "protein localisation to microtubule end" EXACT [GOC:TermGenie] +is_a: GO:0035372 ! protein localization to microtubule +created_by: mah +creation_date: 2016-11-28T15:01:43Z + +[Term] +id: GO:1905735 +name: regulation of L-proline import across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +is_a: GO:1902834 ! regulation of proline import across plasma membrane +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904271 ! L-proline import across plasma membrane +relationship: regulates GO:1904271 ! L-proline import across plasma membrane +created_by: vw +creation_date: 2016-12-04T20:42:16Z + +[Term] +id: GO:1905736 +name: negative regulation of L-proline import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +is_a: GO:1902835 ! negative regulation of proline import across plasma membrane +is_a: GO:1905735 ! regulation of L-proline import across plasma membrane +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904271 ! L-proline import across plasma membrane +relationship: negatively_regulates GO:1904271 ! L-proline import across plasma membrane +created_by: vw +creation_date: 2016-12-04T20:42:24Z + +[Term] +id: GO:1905737 +name: positive regulation of L-proline import across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane." [GO_REF:0000058, GOC:TermGenie, PMID:24344203] +is_a: GO:1902836 ! positive regulation of proline import across plasma membrane +is_a: GO:1905735 ! regulation of L-proline import across plasma membrane +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904271 ! L-proline import across plasma membrane +relationship: positively_regulates GO:1904271 ! L-proline import across plasma membrane +created_by: vw +creation_date: 2016-12-04T20:42:33Z + +[Term] +id: GO:1905741 +name: calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration +namespace: biological_process +def: "Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474] +synonym: "calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration" EXACT [GOC:TermGenie] +synonym: "mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration" EXACT [] +is_a: GO:0099093 ! calcium export from the mitochondrion +is_a: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +intersection_of: GO:0099093 ! calcium export from the mitochondrion +intersection_of: part_of GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +relationship: part_of GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration +created_by: dos +creation_date: 2016-12-06T10:05:01Z + +[Term] +id: GO:1905742 +name: Ras guanyl-nucleotide exchange factor complex +namespace: cellular_component +def: "A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity." [GO_REF:0000088, GOC:rjd, GOC:TermGenie, PMID:20493808] +is_a: GO:0032045 ! guanyl-nucleotide exchange factor complex +created_by: rjd +creation_date: 2016-12-06T10:24:29Z + +[Term] +id: GO:1905743 +name: calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration +namespace: biological_process +def: "Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration." [GO_REF:0000060, GOC:TermGenie, PMID:26644474] +subset: goslim_synapse +synonym: "calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration" EXACT [GOC:TermGenie] +synonym: "mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration" EXACT [] +is_a: GO:0036444 ! calcium import into the mitochondrion +is_a: GO:0051649 ! establishment of localization in cell +intersection_of: GO:0036444 ! calcium import into the mitochondrion +intersection_of: part_of GO:0099113 ! negative regulation of presynaptic cytosolic calcium concentration +relationship: part_of GO:0099113 ! negative regulation of presynaptic cytosolic calcium concentration +created_by: dos +creation_date: 2016-12-06T10:53:17Z + +[Term] +id: GO:1905744 +name: regulation of mRNA cis splicing, via spliceosome +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome." [GO_REF:0000058, GOC:TermGenie, PMID:2880558] +synonym: "regulation of nuclear mRNA cis splicing, via spliceosome" EXACT [GOC:TermGenie] +synonym: "regulation of nuclear mRNA cis splicing, via U2-type spliceosome" NARROW [GOC:TermGenie] +synonym: "regulation of splicing" BROAD [GOC:TermGenie] +is_a: GO:0048024 ! regulation of mRNA splicing, via spliceosome +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045292 ! mRNA cis splicing, via spliceosome +relationship: regulates GO:0045292 ! mRNA cis splicing, via spliceosome +created_by: vw +creation_date: 2016-12-07T14:01:33Z + +[Term] +id: GO:1905745 +name: negative regulation of mRNA cis splicing, via spliceosome +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome." [GO_REF:0000058, GOC:TermGenie, PMID:2880558] +is_a: GO:0048025 ! negative regulation of mRNA splicing, via spliceosome +is_a: GO:1905744 ! regulation of mRNA cis splicing, via spliceosome +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045292 ! mRNA cis splicing, via spliceosome +relationship: negatively_regulates GO:0045292 ! mRNA cis splicing, via spliceosome +created_by: vw +creation_date: 2016-12-07T14:01:42Z + +[Term] +id: GO:1905746 +name: positive regulation of mRNA cis splicing, via spliceosome +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome." [GO_REF:0000058, GOC:TermGenie, PMID:2880558] +is_a: GO:0048026 ! positive regulation of mRNA splicing, via spliceosome +is_a: GO:1905744 ! regulation of mRNA cis splicing, via spliceosome +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045292 ! mRNA cis splicing, via spliceosome +relationship: positively_regulates GO:0045292 ! mRNA cis splicing, via spliceosome +created_by: vw +creation_date: 2016-12-07T14:01:52Z + +[Term] +id: GO:1905747 +name: negative regulation of saliva secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion." [GO_REF:0000058, GOC:TermGenie, PMID:23419067] +synonym: "down regulation of saliva secretion" EXACT [GOC:TermGenie] +synonym: "down regulation of salivation" EXACT [GOC:TermGenie] +synonym: "down-regulation of saliva secretion" EXACT [GOC:TermGenie] +synonym: "down-regulation of salivation" EXACT [GOC:TermGenie] +synonym: "downregulation of saliva secretion" EXACT [GOC:TermGenie] +synonym: "downregulation of salivation" EXACT [GOC:TermGenie] +synonym: "inhibition of saliva secretion" NARROW [GOC:TermGenie] +synonym: "inhibition of salivation" NARROW [GOC:TermGenie] +synonym: "negative regulation of salivation" EXACT [GOC:TermGenie] +is_a: GO:0046877 ! regulation of saliva secretion +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0060457 ! negative regulation of digestive system process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046541 ! saliva secretion +relationship: negatively_regulates GO:0046541 ! saliva secretion +created_by: pga +creation_date: 2016-12-09T10:24:00Z + +[Term] +id: GO:1905748 +name: hard palate morphogenesis +namespace: biological_process +def: "The developmental process by which a hard palate is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:23419067] +synonym: "palatum durum morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: pga +creation_date: 2016-12-09T12:22:24Z + +[Term] +id: GO:1905749 +name: regulation of endosome to plasma membrane protein transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:22869721] +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903076 ! regulation of protein localization to plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0099638 ! endosome to plasma membrane protein transport +relationship: regulates GO:0099638 ! endosome to plasma membrane protein transport +created_by: pga +creation_date: 2016-12-09T13:46:13Z + +[Term] +id: GO:1905750 +name: negative regulation of endosome to plasma membrane protein transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:22869721] +synonym: "down regulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +synonym: "downregulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +synonym: "inhibition of endosome to plasma membrane protein transport" NARROW [GOC:TermGenie] +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane +is_a: GO:1905749 ! regulation of endosome to plasma membrane protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0099638 ! endosome to plasma membrane protein transport +relationship: negatively_regulates GO:0099638 ! endosome to plasma membrane protein transport +created_by: pga +creation_date: 2016-12-09T13:46:21Z + +[Term] +id: GO:1905751 +name: positive regulation of endosome to plasma membrane protein transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:22869721] +synonym: "activation of endosome to plasma membrane protein transport" NARROW [GOC:TermGenie] +synonym: "up regulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +synonym: "upregulation of endosome to plasma membrane protein transport" EXACT [GOC:TermGenie] +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane +is_a: GO:1905749 ! regulation of endosome to plasma membrane protein transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0099638 ! endosome to plasma membrane protein transport +relationship: positively_regulates GO:0099638 ! endosome to plasma membrane protein transport +created_by: pga +creation_date: 2016-12-09T13:46:30Z + +[Term] +id: GO:1905752 +name: regulation of argininosuccinate synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity." [GO_REF:0000059, GOC:TermGenie, PMID:19491403] +synonym: "regulation of arginine succinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of argininosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of argininosuccinic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of arginosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "regulation of citrulline--aspartate ligase activity" EXACT [GOC:TermGenie] +synonym: "regulation of L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [GOC:TermGenie] +is_a: GO:0051340 ! regulation of ligase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004055 ! argininosuccinate synthase activity +relationship: regulates GO:0004055 ! argininosuccinate synthase activity +created_by: dos +creation_date: 2016-12-12T11:43:52Z + +[Term] +id: GO:1905753 +name: positive regulation of argininosuccinate synthase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity." [GO_REF:0000059, GOC:TermGenie, PMID:19491403] +synonym: "activation of arginine succinate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of argininosuccinate synthase activity" NARROW [GOC:TermGenie] +synonym: "activation of argininosuccinate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of argininosuccinic acid synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of arginosuccinate synthetase activity" NARROW [GOC:TermGenie] +synonym: "activation of citrulline--aspartate ligase activity" NARROW [GOC:TermGenie] +synonym: "activation of L-citrulline:L-aspartate ligase (AMP-forming)" NARROW [GOC:TermGenie] +synonym: "positive regulation of arginine succinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of argininosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of argininosuccinic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of arginosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of citrulline--aspartate ligase activity" EXACT [GOC:TermGenie] +synonym: "positive regulation of L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up regulation of arginine succinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of argininosuccinate synthase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of argininosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of argininosuccinic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of arginosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of citrulline--aspartate ligase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginine succinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of argininosuccinate synthase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of argininosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of argininosuccinic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of arginosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of citrulline--aspartate ligase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [GOC:TermGenie] +synonym: "upregulation of arginine succinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of argininosuccinate synthase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of argininosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of argininosuccinic acid synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of arginosuccinate synthetase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of citrulline--aspartate ligase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [GOC:TermGenie] +is_a: GO:0051351 ! positive regulation of ligase activity +is_a: GO:1905752 ! regulation of argininosuccinate synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004055 ! argininosuccinate synthase activity +relationship: positively_regulates GO:0004055 ! argininosuccinate synthase activity +created_by: dos +creation_date: 2016-12-12T11:44:09Z + +[Term] +id: GO:1905754 +name: ascospore-type prospore nucleus +namespace: cellular_component +def: "Any nucleus that is part of a ascospore-type prospore." [GO_REF:0000064, GOC:TermGenie, PMID:26942678] +synonym: "cell nucleus of ascospore-type prospore" EXACT [GOC:TermGenie] +synonym: "nucleus of ascospore-type prospore" EXACT [GOC:TermGenie] +is_a: GO:0005634 ! nucleus +intersection_of: GO:0005634 ! nucleus +intersection_of: part_of GO:0042764 ! ascospore-type prospore +relationship: part_of GO:0042764 ! ascospore-type prospore +created_by: al +creation_date: 2016-12-12T13:25:00Z + +[Term] +id: GO:1905755 +name: protein localization to cytoplasmic microtubule +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] +synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie] +is_a: GO:0035372 ! protein localization to microtubule +created_by: mah +creation_date: 2016-12-12T15:31:07Z + +[Term] +id: GO:1905756 +name: regulation of primary cell septum biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of primary cell septum biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:27898700] +is_a: GO:0140279 ! regulation of mitotic division septum assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0031671 ! primary cell septum biogenesis +relationship: regulates GO:0031671 ! primary cell septum biogenesis +created_by: vw +creation_date: 2016-12-12T18:09:50Z + +[Term] +id: GO:1905757 +name: negative regulation of primary cell septum biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:27898700] +is_a: GO:0140280 ! negative regulation of mitotic division septum assembly +is_a: GO:1905756 ! regulation of primary cell septum biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031671 ! primary cell septum biogenesis +relationship: negatively_regulates GO:0031671 ! primary cell septum biogenesis +created_by: vw +creation_date: 2016-12-12T18:09:59Z + +[Term] +id: GO:1905758 +name: positive regulation of primary cell septum biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:27898700] +is_a: GO:0140281 ! positive regulation of mitotic division septum assembly +is_a: GO:1905756 ! regulation of primary cell septum biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031671 ! primary cell septum biogenesis +relationship: positively_regulates GO:0031671 ! primary cell septum biogenesis +created_by: vw +creation_date: 2016-12-12T18:10:07Z + +[Term] +id: GO:1905759 +name: post-anaphase array microtubule +namespace: cellular_component +def: "Any microtubule that is part of a post-anaphase microtubule array." [GO_REF:0000064, GOC:TermGenie, PMID:11007487] +synonym: "microtubule of PAA" EXACT [GOC:TermGenie] +synonym: "microtubule of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubule of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "microtubuli of PAA" EXACT [GOC:TermGenie] +synonym: "microtubuli of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubuli of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "microtubulus of PAA" EXACT [GOC:TermGenie] +synonym: "microtubulus of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubulus of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "neurotubule of PAA" NARROW [GOC:TermGenie] +synonym: "neurotubule of post-anaphase array" NARROW [GOC:TermGenie] +synonym: "neurotubule of post-anaphase microtubule array" NARROW [GOC:TermGenie] +is_a: GO:0005874 ! microtubule +intersection_of: GO:0005874 ! microtubule +intersection_of: part_of GO:1990295 ! post-anaphase microtubule array +relationship: part_of GO:1990295 ! post-anaphase microtubule array +created_by: dos +creation_date: 2016-12-12T18:36:53Z + +[Term] +id: GO:1905760 +name: post-anaphase array microtubule end +namespace: cellular_component +def: "Any microtubule end that is part of a post-anaphase array microtubule." [GO_REF:0000064, GOC:TermGenie, PMID:11007487] +synonym: "microtubule end of microtubule of PAA" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubule of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubule of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubuli of PAA" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubuli of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubuli of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubulus of PAA" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubulus of post-anaphase array" EXACT [GOC:TermGenie] +synonym: "microtubule end of microtubulus of post-anaphase microtubule array" EXACT [GOC:TermGenie] +synonym: "microtubule end of neurotubule of PAA" NARROW [GOC:TermGenie] +synonym: "microtubule end of neurotubule of post-anaphase array" NARROW [GOC:TermGenie] +synonym: "microtubule end of neurotubule of post-anaphase microtubule array" NARROW [GOC:TermGenie] +synonym: "microtubule end of post-anaphase array microtubule" EXACT [GOC:TermGenie] +is_a: GO:1990752 ! microtubule end +intersection_of: GO:1990752 ! microtubule end +intersection_of: part_of GO:1905759 ! post-anaphase array microtubule +relationship: part_of GO:1905759 ! post-anaphase array microtubule +created_by: dos +creation_date: 2016-12-12T19:38:32Z + +[Term] +id: GO:1905761 +name: SCF ubiquitin ligase complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a SCF ubiquitin ligase complex." [GOC:dph, GOC:ha, GOC:TermGenie, PMID:19723762] +synonym: "CDL1 complex binding" EXACT [GOC:TermGenie] +synonym: "CRL1 complex binding" EXACT [GOC:TermGenie] +synonym: "Cul1-RING ubiquitin ligase complex binding" EXACT [GOC:TermGenie] +synonym: "cullin-RING ligase 1 binding" EXACT [GOC:TermGenie] +synonym: "SCF complex binding" EXACT [GOC:TermGenie] +synonym: "SCF complex substrate recognition subunit binding" NARROW [GOC:TermGenie] +synonym: "Skp1/Cul1/F-box protein complex binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: dph +creation_date: 2016-12-14T15:08:12Z + +[Term] +id: GO:1905762 +name: CCR4-NOT complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a CCR4-NOT complex." [GOC:TermGenie, PMID:26942678] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2016-12-15T15:48:53Z + +[Term] +id: GO:1905763 +name: MTREC complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a MTREC complex." [GOC:TermGenie, PMID:26942678] +synonym: "Mtl1-Red1 core complex binding" EXACT [GOC:TermGenie] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mah +creation_date: 2016-12-15T15:49:02Z + +[Term] +id: GO:1905764 +name: regulation of protection from non-homologous end joining at telomere +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:14690602] +synonym: "regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +is_a: GO:1904353 ! regulation of telomere capping +is_a: GO:1904505 ! regulation of telomere maintenance in response to DNA damage +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031848 ! protection from non-homologous end joining at telomere +relationship: regulates GO:0031848 ! protection from non-homologous end joining at telomere +created_by: nc +creation_date: 2016-12-20T11:28:21Z + +[Term] +id: GO:1905765 +name: negative regulation of protection from non-homologous end joining at telomere +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:14690602] +synonym: "down regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "down regulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +synonym: "down-regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "down-regulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +synonym: "downregulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "downregulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +synonym: "inhibition of protection from NHEJ-mediated telomere fusion" NARROW [GOC:TermGenie] +synonym: "inhibition of protection from non-homologous end joining at telomere" NARROW [GOC:TermGenie] +synonym: "negative regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +is_a: GO:1904354 ! negative regulation of telomere capping +is_a: GO:1904506 ! negative regulation of telomere maintenance in response to DNA damage +is_a: GO:1905764 ! regulation of protection from non-homologous end joining at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031848 ! protection from non-homologous end joining at telomere +relationship: negatively_regulates GO:0031848 ! protection from non-homologous end joining at telomere +created_by: nc +creation_date: 2016-12-20T11:28:30Z + +[Term] +id: GO:1905766 +name: positive regulation of protection from non-homologous end joining at telomere +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:14690602] +synonym: "activation of protection from NHEJ-mediated telomere fusion" NARROW [GOC:TermGenie] +synonym: "activation of protection from non-homologous end joining at telomere" NARROW [GOC:TermGenie] +synonym: "positive regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "up regulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +synonym: "up-regulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "up-regulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +synonym: "upregulation of protection from NHEJ-mediated telomere fusion" EXACT [GOC:TermGenie] +synonym: "upregulation of protection from non-homologous end joining at telomere" EXACT [GOC:TermGenie] +is_a: GO:1904355 ! positive regulation of telomere capping +is_a: GO:1904507 ! positive regulation of telomere maintenance in response to DNA damage +is_a: GO:1905764 ! regulation of protection from non-homologous end joining at telomere +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031848 ! protection from non-homologous end joining at telomere +relationship: positively_regulates GO:0031848 ! protection from non-homologous end joining at telomere +created_by: nc +creation_date: 2016-12-20T11:28:39Z + +[Term] +id: GO:1905767 +name: regulation of double-stranded telomeric DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:18812185] +is_a: GO:1904742 ! regulation of telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003691 ! double-stranded telomeric DNA binding +relationship: regulates GO:0003691 ! double-stranded telomeric DNA binding +created_by: nc +creation_date: 2016-12-20T15:33:58Z + +[Term] +id: GO:1905768 +name: negative regulation of double-stranded telomeric DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:18812185] +synonym: "down regulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "downregulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "inhibition of double-stranded telomeric DNA binding" NARROW [GOC:TermGenie] +is_a: GO:1904743 ! negative regulation of telomeric DNA binding +is_a: GO:1905767 ! regulation of double-stranded telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003691 ! double-stranded telomeric DNA binding +relationship: negatively_regulates GO:0003691 ! double-stranded telomeric DNA binding +created_by: nc +creation_date: 2016-12-20T15:34:07Z + +[Term] +id: GO:1905769 +name: positive regulation of double-stranded telomeric DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:18812185] +synonym: "activation of double-stranded telomeric DNA binding" NARROW [GOC:TermGenie] +synonym: "up regulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +synonym: "upregulation of double-stranded telomeric DNA binding" EXACT [GOC:TermGenie] +is_a: GO:1904744 ! positive regulation of telomeric DNA binding +is_a: GO:1905767 ! regulation of double-stranded telomeric DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003691 ! double-stranded telomeric DNA binding +relationship: positively_regulates GO:0003691 ! double-stranded telomeric DNA binding +created_by: nc +creation_date: 2016-12-20T15:34:15Z + +[Term] +id: GO:1905770 +name: regulation of mesodermal cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] +synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1905902 ! regulation of mesoderm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048333 ! mesodermal cell differentiation +relationship: regulates GO:0048333 ! mesodermal cell differentiation +created_by: rph +creation_date: 2016-12-21T12:44:13Z + +[Term] +id: GO:1905771 +name: negative regulation of mesodermal cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] +synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "inhibition of mesoderm cell differentiation" NARROW [GOC:TermGenie] +synonym: "inhibition of mesodermal cell differentiation" NARROW [GOC:TermGenie] +synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1905770 ! regulation of mesodermal cell differentiation +is_a: GO:1905903 ! negative regulation of mesoderm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048333 ! mesodermal cell differentiation +relationship: negatively_regulates GO:0048333 ! mesodermal cell differentiation +created_by: rph +creation_date: 2016-12-21T12:44:23Z + +[Term] +id: GO:1905772 +name: positive regulation of mesodermal cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] +synonym: "activation of mesoderm cell differentiation" NARROW [GOC:TermGenie] +synonym: "activation of mesodermal cell differentiation" NARROW [GOC:TermGenie] +synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] +synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1905770 ! regulation of mesodermal cell differentiation +is_a: GO:1905904 ! positive regulation of mesoderm formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048333 ! mesodermal cell differentiation +relationship: positively_regulates GO:0048333 ! mesodermal cell differentiation +created_by: rph +creation_date: 2016-12-21T12:44:32Z + +[Term] +id: GO:1905773 +name: 8-hydroxy-2'-deoxyguanosine DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA." [GO_REF:0000067, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:19734539] +is_a: GO:0032357 ! oxidized purine DNA binding +created_by: nc +creation_date: 2016-12-21T15:57:27Z + +[Term] +id: GO:1905774 +name: regulation of DNA helicase activity +namespace: biological_process +alt_id: GO:1902449 +def: "Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:13679365, PMID:19734539] +synonym: "regulation of ATP-dependent DNA helicase activity" EXACT [] +is_a: GO:0051095 ! regulation of helicase activity +is_a: GO:1905462 ! regulation of DNA duplex unwinding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003678 ! DNA helicase activity +relationship: regulates GO:0003678 ! DNA helicase activity +created_by: rb +creation_date: 2013-10-15T21:19:52Z + +[Term] +id: GO:1905775 +name: negative regulation of DNA helicase activity +namespace: biological_process +alt_id: GO:1902450 +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:13679365, PMID:19734539] +synonym: "down regulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "down regulation of DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of ATP-dependent DNA helicase activity" NARROW [GOC:TermGenie] +synonym: "inhibition of DNA helicase activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATP-dependent DNA helicase activity" EXACT [] +is_a: GO:0051097 ! negative regulation of helicase activity +is_a: GO:1905463 ! negative regulation of DNA duplex unwinding +is_a: GO:1905774 ! regulation of DNA helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003678 ! DNA helicase activity +relationship: negatively_regulates GO:0003678 ! DNA helicase activity +created_by: rb +creation_date: 2013-10-15T21:20:01Z + +[Term] +id: GO:1905776 +name: positive regulation of DNA helicase activity +namespace: biological_process +alt_id: GO:1902451 +def: "Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:13679365, PMID:19734539] +synonym: "activation of ATP-dependent DNA helicase activity" NARROW [GOC:TermGenie] +synonym: "activation of DNA helicase activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATP-dependent DNA helicase activity" EXACT [] +synonym: "up regulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "up regulation of DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of ATP-dependent DNA helicase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of DNA helicase activity" EXACT [GOC:TermGenie] +is_a: GO:0051096 ! positive regulation of helicase activity +is_a: GO:1905464 ! positive regulation of DNA duplex unwinding +is_a: GO:1905774 ! regulation of DNA helicase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003678 ! DNA helicase activity +relationship: positively_regulates GO:0003678 ! DNA helicase activity +created_by: rb +creation_date: 2013-10-15T21:20:10Z + +[Term] +id: GO:1905777 +name: regulation of exonuclease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of exonuclease activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +synonym: "regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +is_a: GO:0032069 ! regulation of nuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004527 ! exonuclease activity +relationship: regulates GO:0004527 ! exonuclease activity +created_by: nc +creation_date: 2016-12-21T21:32:07Z + +[Term] +id: GO:1905778 +name: negative regulation of exonuclease activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +synonym: "down regulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "down regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "down-regulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "downregulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "downregulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "inhibition of exonuclease activity" NARROW [GOC:TermGenie] +synonym: "inhibition of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "negative regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +is_a: GO:0032074 ! negative regulation of nuclease activity +is_a: GO:1905777 ! regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004527 ! exonuclease activity +relationship: negatively_regulates GO:0004527 ! exonuclease activity +created_by: nc +creation_date: 2016-12-21T21:32:16Z + +[Term] +id: GO:1905779 +name: positive regulation of exonuclease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of exonuclease activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +synonym: "activation of exonuclease activity" NARROW [GOC:TermGenie] +synonym: "activation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "positive regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "up regulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "up regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "up-regulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of exonuclease IX activity" NARROW [GOC:TermGenie] +synonym: "upregulation of exonuclease activity" EXACT [GOC:TermGenie] +synonym: "upregulation of exonuclease IX activity" NARROW [GOC:TermGenie] +is_a: GO:0032075 ! positive regulation of nuclease activity +is_a: GO:1905777 ! regulation of exonuclease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004527 ! exonuclease activity +relationship: positively_regulates GO:0004527 ! exonuclease activity +created_by: nc +creation_date: 2016-12-21T21:32:24Z + +[Term] +id: GO:1905780 +name: regulation of phosphatidylserine exposure on apoptotic cell surface +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:17401362] +synonym: "regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +is_a: GO:0061091 ! regulation of phospholipid translocation +is_a: GO:1900117 ! regulation of execution phase of apoptosis +is_a: GO:1903729 ! regulation of plasma membrane organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +relationship: regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +created_by: kmv +creation_date: 2017-01-04T15:18:52Z + +[Term] +id: GO:1905781 +name: negative regulation of phosphatidylserine exposure on apoptotic cell surface +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:17401362] +synonym: "down regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "down regulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +synonym: "down-regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "down-regulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +synonym: "downregulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "downregulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +synonym: "inhibition of externalization of phosphatidylserine" NARROW [GOC:TermGenie] +synonym: "inhibition of phosphatidylserine exposure on apoptotic cell surface" NARROW [GOC:TermGenie] +synonym: "negative regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +is_a: GO:0061093 ! negative regulation of phospholipid translocation +is_a: GO:1900118 ! negative regulation of execution phase of apoptosis +is_a: GO:1905780 ! regulation of phosphatidylserine exposure on apoptotic cell surface +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +relationship: negatively_regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +created_by: kmv +creation_date: 2017-01-04T15:19:14Z + +[Term] +id: GO:1905782 +name: positive regulation of phosphatidylserine exposure on apoptotic cell surface +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface." [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:17401362] +synonym: "activation of externalization of phosphatidylserine" NARROW [GOC:TermGenie] +synonym: "activation of phosphatidylserine exposure on apoptotic cell surface" NARROW [GOC:TermGenie] +synonym: "positive regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "up regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "up regulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +synonym: "up-regulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "up-regulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +synonym: "upregulation of externalization of phosphatidylserine" EXACT [GOC:TermGenie] +synonym: "upregulation of phosphatidylserine exposure on apoptotic cell surface" EXACT [GOC:TermGenie] +is_a: GO:0061092 ! positive regulation of phospholipid translocation +is_a: GO:1900119 ! positive regulation of execution phase of apoptosis +is_a: GO:1905780 ! regulation of phosphatidylserine exposure on apoptotic cell surface +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +relationship: positively_regulates GO:0070782 ! phosphatidylserine exposure on apoptotic cell surface +created_by: kmv +creation_date: 2017-01-04T15:19:22Z + +[Term] +id: GO:1905783 +name: CENP-A containing nucleosome disassembly +namespace: biological_process +def: "The disaggregation of a CENP-A containing nucleosome into its constituent components." [GO_REF:0000079, GOC:TermGenie, PMID:27666591] +synonym: "centromere specific nucleosome disassembly" RELATED [GOC:TermGenie] +synonym: "centromere-specific nucleosome disassembly" RELATED [GOC:TermGenie] +synonym: "centromeric nucleosome disassembly" RELATED [GOC:TermGenie] +is_a: GO:0006337 ! nucleosome disassembly +created_by: vw +creation_date: 2017-01-05T09:19:07Z + +[Term] +id: GO:1905784 +name: regulation of anaphase-promoting complex-dependent catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10921876] +is_a: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +relationship: regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +created_by: vw +creation_date: 2017-01-09T10:16:14Z + +[Term] +id: GO:1905785 +name: negative regulation of anaphase-promoting complex-dependent catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10921876] +is_a: GO:0032435 ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1905784 ! regulation of anaphase-promoting complex-dependent catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +relationship: negatively_regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +created_by: vw +creation_date: 2017-01-09T10:16:23Z + +[Term] +id: GO:1905786 +name: positive regulation of anaphase-promoting complex-dependent catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:10921876] +is_a: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +is_a: GO:1905784 ! regulation of anaphase-promoting complex-dependent catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +relationship: positively_regulates GO:0031145 ! anaphase-promoting complex-dependent catabolic process +created_by: vw +creation_date: 2017-01-09T10:16:33Z + +[Term] +id: GO:1905787 +name: regulation of detection of mechanical stimulus involved in sensory perception of touch +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0051931 ! regulation of sensory perception +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +relationship: regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +created_by: hbye +creation_date: 2017-01-09T15:11:04Z + +[Term] +id: GO:1905788 +name: negative regulation of detection of mechanical stimulus involved in sensory perception of touch +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "down regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "down regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "down regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "down regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "down-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "down-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "down-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "downregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "downregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "downregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] +synonym: "inhibition of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] +synonym: "inhibition of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] +synonym: "inhibition of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "negative regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "negative regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "negative regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +is_a: GO:0031645 ! negative regulation of nervous system process +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +relationship: negatively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +created_by: hbye +creation_date: 2017-01-09T15:11:14Z + +[Term] +id: GO:1905789 +name: positive regulation of detection of mechanical stimulus involved in sensory perception of touch +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "activation of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] +synonym: "activation of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "activation of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "activation of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "activation of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] +synonym: "activation of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] +synonym: "activation of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "positive regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "positive regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "up regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "up regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "up regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "up-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "up-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "up-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] +synonym: "upregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "upregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] +synonym: "upregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +relationship: positively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch +created_by: hbye +creation_date: 2017-01-09T15:11:23Z + +[Term] +id: GO:1905790 +name: regulation of mechanosensory behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mechanosensory behavior." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +is_a: GO:0032101 ! regulation of response to external stimulus +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007638 ! mechanosensory behavior +relationship: regulates GO:0007638 ! mechanosensory behavior +created_by: hbye +creation_date: 2017-01-09T15:17:07Z + +[Term] +id: GO:1905791 +name: negative regulation of mechanosensory behavior +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "down regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "down regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "down-regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "down-regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "downregulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "downregulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "inhibition of behavioral response to mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of behavioural response to mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of mechanosensory behavior" NARROW [GOC:TermGenie] +synonym: "inhibition of mechanosensory behaviour" NARROW [GOC:TermGenie] +synonym: "negative regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "negative regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +is_a: GO:0032102 ! negative regulation of response to external stimulus +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:1905790 ! regulation of mechanosensory behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007638 ! mechanosensory behavior +relationship: negatively_regulates GO:0007638 ! mechanosensory behavior +created_by: hbye +creation_date: 2017-01-09T15:17:15Z + +[Term] +id: GO:1905792 +name: positive regulation of mechanosensory behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mechanosensory behavior." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] +synonym: "activation of behavioral response to mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "activation of behavioural response to mechanical stimulus" NARROW [GOC:TermGenie] +synonym: "activation of mechanosensory behavior" NARROW [GOC:TermGenie] +synonym: "activation of mechanosensory behaviour" NARROW [GOC:TermGenie] +synonym: "positive regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "positive regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "up regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "up regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "up-regulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "up-regulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +synonym: "upregulation of behavioral response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of behavioural response to mechanical stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of mechanosensory behavior" EXACT [GOC:TermGenie] +synonym: "upregulation of mechanosensory behaviour" EXACT [GOC:TermGenie] +is_a: GO:0032103 ! positive regulation of response to external stimulus +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:1905790 ! regulation of mechanosensory behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007638 ! mechanosensory behavior +relationship: positively_regulates GO:0007638 ! mechanosensory behavior +created_by: hbye +creation_date: 2017-01-09T15:17:24Z + +[Term] +id: GO:1905793 +name: protein localization to pericentriolar material +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a pericentriolar material." [GO_REF:0000087, GOC:TermGenie, PMID:21694707, PMID:24385583] +synonym: "protein localisation in pericentriolar material" EXACT [GOC:TermGenie] +synonym: "protein localisation to pericentriolar material" EXACT [GOC:TermGenie] +synonym: "protein localization in pericentriolar material" EXACT [GOC:TermGenie] +is_a: GO:0071539 ! protein localization to centrosome +created_by: ha +creation_date: 2017-01-10T11:10:37Z + +[Term] +id: GO:1905794 +name: response to puromycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25736288] +synonym: "response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine" EXACT [] +is_a: GO:0014074 ! response to purine-containing compound +is_a: GO:0046677 ! response to antibiotic +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2017-01-10T21:13:18Z + +[Term] +id: GO:1905795 +name: cellular response to puromycin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:25736288] +synonym: "cellular response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine" EXACT [] +is_a: GO:0035690 ! cellular response to drug +is_a: GO:0071236 ! cellular response to antibiotic +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905794 ! response to puromycin +created_by: sl +creation_date: 2017-01-10T21:13:28Z + +[Term] +id: GO:1905796 +name: regulation of intraciliary anterograde transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intraciliary anterograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0060632 ! regulation of microtubule-based movement +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035720 ! intraciliary anterograde transport +relationship: regulates GO:0035720 ! intraciliary anterograde transport +created_by: hbye +creation_date: 2017-01-11T12:55:35Z + +[Term] +id: GO:1905797 +name: negative regulation of intraciliary anterograde transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "down regulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "down regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "downregulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "downregulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "inhibition of intraciliary anterograde transport" NARROW [GOC:TermGenie] +synonym: "inhibition of intraflagellar anterograde transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1905796 ! regulation of intraciliary anterograde transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035720 ! intraciliary anterograde transport +relationship: negatively_regulates GO:0035720 ! intraciliary anterograde transport +created_by: hbye +creation_date: 2017-01-11T12:55:53Z + +[Term] +id: GO:1905798 +name: positive regulation of intraciliary anterograde transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "activation of intraciliary anterograde transport" NARROW [GOC:TermGenie] +synonym: "activation of intraflagellar anterograde transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "up regulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "up regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +synonym: "upregulation of intraciliary anterograde transport" EXACT [GOC:TermGenie] +synonym: "upregulation of intraflagellar anterograde transport" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1905796 ! regulation of intraciliary anterograde transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035720 ! intraciliary anterograde transport +relationship: positively_regulates GO:0035720 ! intraciliary anterograde transport +created_by: hbye +creation_date: 2017-01-11T12:56:01Z + +[Term] +id: GO:1905799 +name: regulation of intraciliary retrograde transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intraciliary retrograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0033157 ! regulation of intracellular protein transport +is_a: GO:0060632 ! regulation of microtubule-based movement +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035721 ! intraciliary retrograde transport +relationship: regulates GO:0035721 ! intraciliary retrograde transport +created_by: hbye +creation_date: 2017-01-11T12:58:18Z + +[Term] +id: GO:1905800 +name: negative regulation of intraciliary retrograde transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "down regulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "down regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "downregulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "downregulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "inhibition of intraciliary retrograde transport" NARROW [GOC:TermGenie] +synonym: "inhibition of intraflagellar retrograde transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:0090317 ! negative regulation of intracellular protein transport +is_a: GO:1905799 ! regulation of intraciliary retrograde transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035721 ! intraciliary retrograde transport +relationship: negatively_regulates GO:0035721 ! intraciliary retrograde transport +created_by: hbye +creation_date: 2017-01-11T12:58:26Z + +[Term] +id: GO:1905801 +name: positive regulation of intraciliary retrograde transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport." [GO_REF:0000058, GOC:TermGenie, PMID:27930654] +synonym: "activation of intraciliary retrograde transport" NARROW [GOC:TermGenie] +synonym: "activation of intraflagellar retrograde transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "up regulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "up regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +synonym: "upregulation of intraciliary retrograde transport" EXACT [GOC:TermGenie] +synonym: "upregulation of intraflagellar retrograde transport" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:0090316 ! positive regulation of intracellular protein transport +is_a: GO:1905799 ! regulation of intraciliary retrograde transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035721 ! intraciliary retrograde transport +relationship: positively_regulates GO:0035721 ! intraciliary retrograde transport +created_by: hbye +creation_date: 2017-01-11T12:58:35Z + +[Term] +id: GO:1905802 +name: regulation of cellular response to manganese ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to manganese ion." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +synonym: "regulation of cellular response to manganese" EXACT [GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071287 ! cellular response to manganese ion +relationship: regulates GO:0071287 ! cellular response to manganese ion +created_by: pga +creation_date: 2017-01-11T14:59:39Z + +[Term] +id: GO:1905803 +name: negative regulation of cellular response to manganese ion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +synonym: "down regulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to manganese" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to manganese ion" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to manganese" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905802 ! regulation of cellular response to manganese ion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071287 ! cellular response to manganese ion +relationship: negatively_regulates GO:0071287 ! cellular response to manganese ion +created_by: pga +creation_date: 2017-01-11T14:59:48Z + +[Term] +id: GO:1905804 +name: positive regulation of cellular response to manganese ion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +synonym: "activation of cellular response to manganese" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to manganese ion" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to manganese" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to manganese ion" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905802 ! regulation of cellular response to manganese ion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071287 ! cellular response to manganese ion +relationship: positively_regulates GO:0071287 ! cellular response to manganese ion +created_by: pga +creation_date: 2017-01-11T14:59:57Z + +[Term] +id: GO:1905805 +name: excitatory synapse pruning +namespace: biological_process +def: "The disaggregation of an excitatory synapse into its constituent components." [GO_REF:0000079, GOC:TermGenie, PMID:27779093] +synonym: "synapse clearance" BROAD [] +synonym: "synapse disassembly" BROAD [] +synonym: "synapse elimination" BROAD [] +synonym: "synapse removal" BROAD [] +is_a: GO:0098883 ! synapse pruning +created_by: tb +creation_date: 2017-01-11T22:03:06Z + +[Term] +id: GO:1905806 +name: regulation of synapse pruning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +subset: goslim_synapse +synonym: "regulation of synapse clearance" EXACT [] +synonym: "regulation of synapse disassembly" EXACT syngo_official_label [] +synonym: "regulation of synapse elimination" EXACT [] +synonym: "regulation of synapse removal" EXACT [] +is_a: GO:0050807 ! regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0098883 ! synapse pruning +relationship: regulates GO:0098883 ! synapse pruning +created_by: tb +creation_date: 2017-01-11T22:03:15Z + +[Term] +id: GO:1905807 +name: negative regulation of synapse pruning +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of synapse disassembly" NARROW [GOC:TermGenie] +synonym: "regulation of synapse clearance" BROAD [] +synonym: "regulation of synapse disassembly" BROAD [] +synonym: "regulation of synapse elimination" BROAD [] +synonym: "regulation of synapse removal" BROAD [] +is_a: GO:1905806 ! regulation of synapse pruning +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0098883 ! synapse pruning +relationship: negatively_regulates GO:0098883 ! synapse pruning +created_by: tb +creation_date: 2017-01-11T22:03:24Z + +[Term] +id: GO:1905808 +name: positive regulation of synapse pruning +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "activation of synapse disassembly" NARROW [GOC:TermGenie] +synonym: "regulation of synapse clearance" BROAD [] +synonym: "regulation of synapse disassembly" BROAD [] +synonym: "regulation of synapse elimination" BROAD [] +synonym: "regulation of synapse removal" BROAD [] +synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1905806 ! regulation of synapse pruning +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0098883 ! synapse pruning +relationship: positively_regulates GO:0098883 ! synapse pruning +created_by: tb +creation_date: 2017-01-11T22:03:33Z + +[Term] +id: GO:1905809 +name: negative regulation of synapse organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "down regulation of synapse development" EXACT [GOC:TermGenie] +synonym: "down regulation of synapse morphogenesis" RELATED [GOC:TermGenie] +synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie] +synonym: "down regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie] +synonym: "down-regulation of synapse morphogenesis" RELATED [GOC:TermGenie] +synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of synapse development" EXACT [GOC:TermGenie] +synonym: "downregulation of synapse morphogenesis" RELATED [GOC:TermGenie] +synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie] +synonym: "downregulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of synapse development" NARROW [GOC:TermGenie] +synonym: "inhibition of synapse morphogenesis" RELATED [GOC:TermGenie] +synonym: "inhibition of synapse organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of synapse organization" NARROW [GOC:TermGenie] +synonym: "inhibition of synapse organization and biogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie] +synonym: "negative regulation of synapse morphogenesis" RELATED [GOC:TermGenie] +synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] +is_a: GO:0050807 ! regulation of synapse organization +is_a: GO:0051129 ! negative regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050808 ! synapse organization +relationship: negatively_regulates GO:0050808 ! synapse organization +created_by: tb +creation_date: 2017-01-11T22:03:41Z + +[Term] +id: GO:1905810 +name: regulation of excitatory synapse pruning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of excitatory synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "regulation of synapse clearance" BROAD [] +synonym: "regulation of synapse disassembly" BROAD [] +synonym: "regulation of synapse elimination" BROAD [] +synonym: "regulation of synapse removal" BROAD [] +is_a: GO:1905806 ! regulation of synapse pruning +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905805 ! excitatory synapse pruning +relationship: regulates GO:1905805 ! excitatory synapse pruning +created_by: tb +creation_date: 2017-01-12T02:38:27Z + +[Term] +id: GO:1905811 +name: negative regulation of excitatory synapse pruning +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] +synonym: "down regulation of excitatory synapse disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of excitatory synapse disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of excitatory synapse disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of excitatory synapse disassembly" NARROW [GOC:TermGenie] +synonym: "regulation of synapse clearance" BROAD [] +synonym: "regulation of synapse disassembly" BROAD [] +synonym: "regulation of synapse elimination" BROAD [] +synonym: "regulation of synapse removal" BROAD [] +is_a: GO:1905807 ! negative regulation of synapse pruning +is_a: GO:1905810 ! regulation of excitatory synapse pruning +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905805 ! excitatory synapse pruning +relationship: negatively_regulates GO:1905805 ! excitatory synapse pruning +created_by: tb +creation_date: 2017-01-12T02:38:36Z + +[Term] +id: GO:1905812 +name: regulation of motor neuron axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of motor neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008045 ! motor neuron axon guidance +relationship: regulates GO:0008045 ! motor neuron axon guidance +created_by: hbye +creation_date: 2017-01-12T13:25:12Z + +[Term] +id: GO:1905813 +name: negative regulation of motor neuron axon guidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "down regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down regulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "downregulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "inhibition of motoneuron axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of motor axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of motor axon pathfinding" NARROW [GOC:TermGenie] +synonym: "inhibition of motor neuron axon guidance" NARROW [GOC:TermGenie] +synonym: "negative regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "negative regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "negative regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +is_a: GO:1902668 ! negative regulation of axon guidance +is_a: GO:1905812 ! regulation of motor neuron axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008045 ! motor neuron axon guidance +relationship: negatively_regulates GO:0008045 ! motor neuron axon guidance +created_by: hbye +creation_date: 2017-01-12T13:25:21Z + +[Term] +id: GO:1905814 +name: positive regulation of motor neuron axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "activation of motoneuron axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of motor axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of motor axon pathfinding" NARROW [GOC:TermGenie] +synonym: "activation of motor neuron axon guidance" NARROW [GOC:TermGenie] +synonym: "positive regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "positive regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "positive regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of motoneuron axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of motor axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of motor axon pathfinding" EXACT [GOC:TermGenie] +synonym: "upregulation of motor neuron axon guidance" EXACT [GOC:TermGenie] +is_a: GO:1902669 ! positive regulation of axon guidance +is_a: GO:1905812 ! regulation of motor neuron axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008045 ! motor neuron axon guidance +relationship: positively_regulates GO:0008045 ! motor neuron axon guidance +created_by: hbye +creation_date: 2017-01-12T13:25:31Z + +[Term] +id: GO:1905815 +name: regulation of dorsal/ventral axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033563 ! dorsal/ventral axon guidance +relationship: regulates GO:0033563 ! dorsal/ventral axon guidance +created_by: hbye +creation_date: 2017-01-12T13:38:44Z + +[Term] +id: GO:1905816 +name: negative regulation of dorsal/ventral axon guidance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "down regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "down regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "down-regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "down-regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "downregulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "downregulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "inhibition of dorsal-ventral axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of dorsal/ventral axon guidance" NARROW [GOC:TermGenie] +synonym: "inhibition of dorsal/ventral axon pathfinding" NARROW [GOC:TermGenie] +synonym: "inhibition of dorsoventral axon guidance" NARROW [GOC:TermGenie] +synonym: "negative regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "negative regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "negative regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +is_a: GO:1902668 ! negative regulation of axon guidance +is_a: GO:1905815 ! regulation of dorsal/ventral axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033563 ! dorsal/ventral axon guidance +relationship: negatively_regulates GO:0033563 ! dorsal/ventral axon guidance +created_by: hbye +creation_date: 2017-01-12T13:38:53Z + +[Term] +id: GO:1905817 +name: positive regulation of dorsal/ventral axon guidance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance." [GO_REF:0000058, GOC:TermGenie, PMID:18434533] +synonym: "activation of dorsal-ventral axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of dorsal/ventral axon guidance" NARROW [GOC:TermGenie] +synonym: "activation of dorsal/ventral axon pathfinding" NARROW [GOC:TermGenie] +synonym: "activation of dorsoventral axon guidance" NARROW [GOC:TermGenie] +synonym: "positive regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "positive regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "positive regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "up-regulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "up-regulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of dorsal-ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of dorsal/ventral axon guidance" EXACT [GOC:TermGenie] +synonym: "upregulation of dorsal/ventral axon pathfinding" EXACT [GOC:TermGenie] +synonym: "upregulation of dorsoventral axon guidance" EXACT [GOC:TermGenie] +is_a: GO:1902669 ! positive regulation of axon guidance +is_a: GO:1905815 ! regulation of dorsal/ventral axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033563 ! dorsal/ventral axon guidance +relationship: positively_regulates GO:0033563 ! dorsal/ventral axon guidance +created_by: hbye +creation_date: 2017-01-12T13:39:01Z + +[Term] +id: GO:1905818 +name: regulation of chromosome separation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chromosome separation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:21795393] +synonym: "regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "regulation of rDNA separation" NARROW [GOC:TermGenie] +is_a: GO:0010564 ! regulation of cell cycle process +is_a: GO:0051983 ! regulation of chromosome segregation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051304 ! chromosome separation +relationship: regulates GO:0051304 ! chromosome separation +created_by: bhm +creation_date: 2017-01-13T13:55:18Z + +[Term] +id: GO:1905819 +name: negative regulation of chromosome separation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:21795393] +synonym: "down regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "down regulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "down regulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "down-regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "down-regulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "down-regulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "downregulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "downregulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "downregulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "inhibition of chromatid release" RELATED [GOC:TermGenie] +synonym: "inhibition of chromosome separation" NARROW [GOC:TermGenie] +synonym: "inhibition of rDNA separation" NARROW [GOC:TermGenie] +synonym: "negative regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "negative regulation of rDNA separation" NARROW [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0051985 ! negative regulation of chromosome segregation +is_a: GO:1905818 ! regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051304 ! chromosome separation +relationship: negatively_regulates GO:0051304 ! chromosome separation +created_by: bhm +creation_date: 2017-01-13T13:55:27Z + +[Term] +id: GO:1905820 +name: positive regulation of chromosome separation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromosome separation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:21795393] +synonym: "activation of chromatid release" RELATED [GOC:TermGenie] +synonym: "activation of chromosome separation" NARROW [GOC:TermGenie] +synonym: "activation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "positive regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "positive regulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "up regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "up regulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "up regulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "up-regulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "up-regulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "up-regulation of rDNA separation" NARROW [GOC:TermGenie] +synonym: "upregulation of chromatid release" RELATED [GOC:TermGenie] +synonym: "upregulation of chromosome separation" EXACT [GOC:TermGenie] +synonym: "upregulation of rDNA separation" NARROW [GOC:TermGenie] +is_a: GO:0051984 ! positive regulation of chromosome segregation +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:1905818 ! regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051304 ! chromosome separation +relationship: positively_regulates GO:0051304 ! chromosome separation +created_by: bhm +creation_date: 2017-01-13T13:55:36Z + +[Term] +id: GO:1905821 +name: positive regulation of chromosome condensation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547] +synonym: "activation of chromosome condensation" NARROW [GOC:TermGenie] +synonym: "activation of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] +synonym: "activation of nuclear chromosome condensation" NARROW [GOC:TermGenie] +synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie] +synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] +synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] +is_a: GO:0060623 ! regulation of chromosome condensation +is_a: GO:2001252 ! positive regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030261 ! chromosome condensation +relationship: positively_regulates GO:0030261 ! chromosome condensation +created_by: bhm +creation_date: 2017-01-13T14:13:44Z + +[Term] +id: GO:1905822 +name: regulation of mitotic sister chromatid arm separation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18765790] +is_a: GO:0010965 ! regulation of mitotic sister chromatid separation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990891 ! mitotic sister chromatid arm separation +relationship: regulates GO:1990891 ! mitotic sister chromatid arm separation +created_by: als +creation_date: 2017-01-16T13:36:29Z + +[Term] +id: GO:1905823 +name: negative regulation of mitotic sister chromatid arm separation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18765790] +synonym: "down regulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +synonym: "downregulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +synonym: "inhibition of mitotic sister chromatid arm separation" NARROW [GOC:TermGenie] +is_a: GO:1905822 ! regulation of mitotic sister chromatid arm separation +is_a: GO:2000816 ! negative regulation of mitotic sister chromatid separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990891 ! mitotic sister chromatid arm separation +relationship: negatively_regulates GO:1990891 ! mitotic sister chromatid arm separation +created_by: als +creation_date: 2017-01-16T13:36:38Z + +[Term] +id: GO:1905824 +name: positive regulation of mitotic sister chromatid arm separation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18765790] +synonym: "activation of mitotic sister chromatid arm separation" NARROW [GOC:TermGenie] +synonym: "up regulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +synonym: "upregulation of mitotic sister chromatid arm separation" EXACT [GOC:TermGenie] +is_a: GO:1901970 ! positive regulation of mitotic sister chromatid separation +is_a: GO:1905822 ! regulation of mitotic sister chromatid arm separation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990891 ! mitotic sister chromatid arm separation +relationship: positively_regulates GO:1990891 ! mitotic sister chromatid arm separation +created_by: als +creation_date: 2017-01-16T13:36:47Z + +[Term] +id: GO:1905825 +name: regulation of selenocysteine metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of selenocysteine metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:19716792] +synonym: "regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016259 ! selenocysteine metabolic process +relationship: regulates GO:0016259 ! selenocysteine metabolic process +created_by: sl +creation_date: 2017-01-16T19:01:34Z + +[Term] +id: GO:1905826 +name: negative regulation of selenocysteine metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:19716792] +synonym: "down regulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "inhibition of selenocysteine metabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of selenocysteine metabolism" NARROW [GOC:TermGenie] +synonym: "negative regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:1905825 ! regulation of selenocysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016259 ! selenocysteine metabolic process +relationship: negatively_regulates GO:0016259 ! selenocysteine metabolic process +created_by: sl +creation_date: 2017-01-16T19:01:42Z + +[Term] +id: GO:1905827 +name: positive regulation of selenocysteine metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:19716792] +synonym: "activation of selenocysteine metabolic process" NARROW [GOC:TermGenie] +synonym: "activation of selenocysteine metabolism" NARROW [GOC:TermGenie] +synonym: "positive regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of selenocysteine metabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of selenocysteine metabolism" EXACT [GOC:TermGenie] +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:1905825 ! regulation of selenocysteine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016259 ! selenocysteine metabolic process +relationship: positively_regulates GO:0016259 ! selenocysteine metabolic process +created_by: sl +creation_date: 2017-01-16T19:01:50Z + +[Term] +id: GO:1905828 +name: regulation of prostaglandin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of prostaglandin catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:12432938] +synonym: "regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +is_a: GO:0019217 ! regulation of fatty acid metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905344 ! prostaglandin catabolic process +relationship: regulates GO:1905344 ! prostaglandin catabolic process +created_by: sl +creation_date: 2017-01-16T21:36:39Z + +[Term] +id: GO:1905829 +name: negative regulation of prostaglandin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:12432938] +synonym: "down regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "down regulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "down regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "down-regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "down-regulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "downregulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "downregulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "downregulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "inhibition of prostaglandin breakdown" NARROW [GOC:TermGenie] +synonym: "inhibition of prostaglandin catabolic process" NARROW [GOC:TermGenie] +synonym: "inhibition of prostaglandin catabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of prostaglandin degradation" NARROW [GOC:TermGenie] +synonym: "negative regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "negative regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045922 ! negative regulation of fatty acid metabolic process +is_a: GO:0050995 ! negative regulation of lipid catabolic process +is_a: GO:1905828 ! regulation of prostaglandin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905344 ! prostaglandin catabolic process +relationship: negatively_regulates GO:1905344 ! prostaglandin catabolic process +created_by: sl +creation_date: 2017-01-16T21:36:48Z + +[Term] +id: GO:1905830 +name: positive regulation of prostaglandin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:12432938] +synonym: "activation of prostaglandin breakdown" NARROW [GOC:TermGenie] +synonym: "activation of prostaglandin catabolic process" NARROW [GOC:TermGenie] +synonym: "activation of prostaglandin catabolism" NARROW [GOC:TermGenie] +synonym: "activation of prostaglandin degradation" NARROW [GOC:TermGenie] +synonym: "positive regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "positive regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "up regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "up regulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "up regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "up-regulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "up-regulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of prostaglandin degradation" EXACT [GOC:TermGenie] +synonym: "upregulation of prostaglandin breakdown" EXACT [GOC:TermGenie] +synonym: "upregulation of prostaglandin catabolic process" EXACT [GOC:TermGenie] +synonym: "upregulation of prostaglandin catabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of prostaglandin degradation" EXACT [GOC:TermGenie] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045923 ! positive regulation of fatty acid metabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:1905828 ! regulation of prostaglandin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905344 ! prostaglandin catabolic process +relationship: positively_regulates GO:1905344 ! prostaglandin catabolic process +created_by: sl +creation_date: 2017-01-16T21:36:56Z + +[Term] +id: GO:1905831 +name: negative regulation of spindle assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] +synonym: "down regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "down regulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "downregulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "inhibition of bipolar spindle biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of bipolar spindle formation" NARROW [GOC:TermGenie] +synonym: "inhibition of spindle assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of spindle biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of spindle formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of spindle formation" EXACT [GOC:TermGenie] +is_a: GO:0010948 ! negative regulation of cell cycle process +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:0090169 ! regulation of spindle assembly +is_a: GO:1902116 ! negative regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051225 ! spindle assembly +relationship: negatively_regulates GO:0051225 ! spindle assembly +created_by: hbye +creation_date: 2017-01-17T10:26:37Z + +[Term] +id: GO:1905832 +name: positive regulation of spindle assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of spindle assembly." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] +synonym: "activation of bipolar spindle biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of bipolar spindle formation" NARROW [GOC:TermGenie] +synonym: "activation of spindle assembly" NARROW [GOC:TermGenie] +synonym: "activation of spindle biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of spindle formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of spindle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of bipolar spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of bipolar spindle formation" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of spindle formation" EXACT [GOC:TermGenie] +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:0090068 ! positive regulation of cell cycle process +is_a: GO:0090169 ! regulation of spindle assembly +is_a: GO:1902117 ! positive regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051225 ! spindle assembly +relationship: positively_regulates GO:0051225 ! spindle assembly +created_by: hbye +creation_date: 2017-01-17T10:26:46Z + +[Term] +id: GO:1905833 +name: negative regulation of microtubule nucleation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] +synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie] +synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie] +synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie] +synonym: "inhibition of microtubule nucleation" NARROW [GOC:TermGenie] +is_a: GO:0010968 ! regulation of microtubule nucleation +is_a: GO:0031115 ! negative regulation of microtubule polymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007020 ! microtubule nucleation +relationship: negatively_regulates GO:0007020 ! microtubule nucleation +created_by: hbye +creation_date: 2017-01-17T12:00:56Z + +[Term] +id: GO:1905834 +name: response to pyrimidine ribonucleotide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22065602] +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0046683 ! response to organophosphorus +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: sl +creation_date: 2017-01-17T19:23:59Z + +[Term] +id: GO:1905835 +name: cellular response to pyrimidine ribonucleotide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:22065602] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:0071417 ! cellular response to organonitrogen compound +is_a: GO:1901701 ! cellular response to oxygen-containing compound +is_a: GO:1905834 ! response to pyrimidine ribonucleotide +created_by: sl +creation_date: 2017-01-17T19:24:09Z + +[Term] +id: GO:1905836 +name: response to triterpenoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:28078994] +is_a: GO:0033993 ! response to lipid +created_by: sl +creation_date: 2017-01-17T19:37:36Z + +[Term] +id: GO:1905837 +name: cellular response to triterpenoid +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:28078994] +is_a: GO:0071396 ! cellular response to lipid +is_a: GO:1905836 ! response to triterpenoid +created_by: sl +creation_date: 2017-01-17T19:37:44Z + +[Term] +id: GO:1905838 +name: regulation of telomeric D-loop disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +is_a: GO:1904533 ! regulation of telomeric loop disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061820 ! telomeric D-loop disassembly +relationship: regulates GO:0061820 ! telomeric D-loop disassembly +created_by: nc +creation_date: 2017-01-18T11:01:38Z + +[Term] +id: GO:1905839 +name: negative regulation of telomeric D-loop disassembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +synonym: "down regulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of telomeric D-loop disassembly" NARROW [GOC:TermGenie] +is_a: GO:1904534 ! negative regulation of telomeric loop disassembly +is_a: GO:1905838 ! regulation of telomeric D-loop disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061820 ! telomeric D-loop disassembly +relationship: negatively_regulates GO:0061820 ! telomeric D-loop disassembly +created_by: nc +creation_date: 2017-01-18T11:01:47Z + +[Term] +id: GO:1905840 +name: positive regulation of telomeric D-loop disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] +synonym: "activation of telomeric D-loop disassembly" NARROW [GOC:TermGenie] +synonym: "up regulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of telomeric D-loop disassembly" EXACT [GOC:TermGenie] +is_a: GO:1904535 ! positive regulation of telomeric loop disassembly +is_a: GO:1905838 ! regulation of telomeric D-loop disassembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061820 ! telomeric D-loop disassembly +relationship: positively_regulates GO:0061820 ! telomeric D-loop disassembly +created_by: nc +creation_date: 2017-01-18T11:01:55Z + +[Term] +id: GO:1905841 +name: response to oxidopamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus." [GO_REF:0000071, GOC:rz, GOC:TermGenie, PMID:23721876] +is_a: GO:0009636 ! response to toxic substance +is_a: GO:0071869 ! response to catecholamine +created_by: pr +creation_date: 2017-01-19T09:49:03Z + +[Term] +id: GO:1905842 +name: cellular response to oxidopamine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus." [GO_REF:0000071, GOC:rz, GOC:TermGenie, PMID:23721876] +is_a: GO:0071870 ! cellular response to catecholamine stimulus +is_a: GO:0097237 ! cellular response to toxic substance +is_a: GO:1905841 ! response to oxidopamine +created_by: pr +creation_date: 2017-01-19T09:49:12Z + +[Term] +id: GO:1905843 +name: regulation of cellular response to gamma radiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to gamma radiation." [GO_REF:0000058, GOC:TermGenie, PMID:23505386] +synonym: "regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:2001228 ! regulation of response to gamma radiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071480 ! cellular response to gamma radiation +relationship: regulates GO:0071480 ! cellular response to gamma radiation +created_by: rz +creation_date: 2017-01-19T10:24:39Z + +[Term] +id: GO:1905844 +name: negative regulation of cellular response to gamma radiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation." [GO_REF:0000058, GOC:TermGenie, PMID:23505386] +synonym: "down regulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "down regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "down-regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "downregulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "inhibition of cellular response to gamma radiation" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "inhibition of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "negative regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "negative regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1905843 ! regulation of cellular response to gamma radiation +is_a: GO:2001229 ! negative regulation of response to gamma radiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071480 ! cellular response to gamma radiation +relationship: negatively_regulates GO:0071480 ! cellular response to gamma radiation +created_by: rz +creation_date: 2017-01-19T10:24:48Z + +[Term] +id: GO:1905845 +name: positive regulation of cellular response to gamma radiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation." [GO_REF:0000058, GOC:TermGenie, PMID:23505386] +synonym: "activation of cellular response to gamma radiation" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "activation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "positive regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "positive regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "up regulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "up regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "up-regulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "up-regulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +synonym: "upregulation of cellular response to gamma radiation" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to gamma ray" RELATED [GOC:TermGenie] +synonym: "upregulation of cellular response to gamma-ray photon" RELATED [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1905843 ! regulation of cellular response to gamma radiation +is_a: GO:2001230 ! positive regulation of response to gamma radiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071480 ! cellular response to gamma radiation +relationship: positively_regulates GO:0071480 ! cellular response to gamma radiation +created_by: rz +creation_date: 2017-01-19T10:24:57Z + +[Term] +id: GO:1905846 +name: regulation of cellular response to oxidopamine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to oxidopamine." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1905842 ! cellular response to oxidopamine +relationship: regulates GO:1905842 ! cellular response to oxidopamine +created_by: rz +creation_date: 2017-01-19T10:46:46Z + +[Term] +id: GO:1905847 +name: negative regulation of cellular response to oxidopamine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +synonym: "down regulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to oxidopamine" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905846 ! regulation of cellular response to oxidopamine +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1905842 ! cellular response to oxidopamine +relationship: negatively_regulates GO:1905842 ! cellular response to oxidopamine +created_by: rz +creation_date: 2017-01-19T10:46:55Z + +[Term] +id: GO:1905848 +name: positive regulation of cellular response to oxidopamine +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine." [GO_REF:0000058, GOC:TermGenie, PMID:23721876] +synonym: "activation of cellular response to oxidopamine" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to oxidopamine" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905846 ! regulation of cellular response to oxidopamine +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1905842 ! cellular response to oxidopamine +relationship: positively_regulates GO:1905842 ! cellular response to oxidopamine +created_by: rz +creation_date: 2017-01-19T10:47:04Z + +[Term] +id: GO:1905849 +name: negative regulation of forward locomotion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion." [GO_REF:0000058, GOC:TermGenie, PMID:11717360] +synonym: "down regulation of forward locomotion" EXACT [GOC:TermGenie] +synonym: "down-regulation of forward locomotion" EXACT [GOC:TermGenie] +synonym: "downregulation of forward locomotion" EXACT [GOC:TermGenie] +synonym: "inhibition of forward locomotion" NARROW [GOC:TermGenie] +is_a: GO:0040013 ! negative regulation of locomotion +is_a: GO:0043059 ! regulation of forward locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043056 ! forward locomotion +relationship: negatively_regulates GO:0043056 ! forward locomotion +created_by: rz +creation_date: 2017-01-23T11:03:55Z + +[Term] +id: GO:1905850 +name: positive regulation of forward locomotion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of forward locomotion." [GO_REF:0000058, GOC:TermGenie, PMID:11717360] +synonym: "activation of forward locomotion" NARROW [GOC:TermGenie] +synonym: "up regulation of forward locomotion" EXACT [GOC:TermGenie] +synonym: "up-regulation of forward locomotion" EXACT [GOC:TermGenie] +synonym: "upregulation of forward locomotion" EXACT [GOC:TermGenie] +is_a: GO:0040017 ! positive regulation of locomotion +is_a: GO:0043059 ! regulation of forward locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043056 ! forward locomotion +relationship: positively_regulates GO:0043056 ! forward locomotion +created_by: rz +creation_date: 2017-01-23T11:04:05Z + +[Term] +id: GO:1905851 +name: negative regulation of backward locomotion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion." [GO_REF:0000058, GOC:TermGenie, PMID:11717360] +synonym: "down regulation of backward locomotion" EXACT [GOC:TermGenie] +synonym: "down-regulation of backward locomotion" EXACT [GOC:TermGenie] +synonym: "downregulation of backward locomotion" EXACT [GOC:TermGenie] +synonym: "inhibition of backward locomotion" NARROW [GOC:TermGenie] +is_a: GO:0040013 ! negative regulation of locomotion +is_a: GO:0043058 ! regulation of backward locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043057 ! backward locomotion +relationship: negatively_regulates GO:0043057 ! backward locomotion +created_by: rz +creation_date: 2017-01-23T11:04:16Z + +[Term] +id: GO:1905852 +name: positive regulation of backward locomotion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of backward locomotion." [GO_REF:0000058, GOC:TermGenie, PMID:11717360] +synonym: "activation of backward locomotion" NARROW [GOC:TermGenie] +synonym: "up regulation of backward locomotion" EXACT [GOC:TermGenie] +synonym: "up-regulation of backward locomotion" EXACT [GOC:TermGenie] +synonym: "upregulation of backward locomotion" EXACT [GOC:TermGenie] +is_a: GO:0040017 ! positive regulation of locomotion +is_a: GO:0043058 ! regulation of backward locomotion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043057 ! backward locomotion +relationship: positively_regulates GO:0043057 ! backward locomotion +created_by: rz +creation_date: 2017-01-23T11:04:25Z + +[Term] +id: GO:1905853 +name: regulation of heparan sulfate binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heparan sulfate binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +is_a: GO:0051098 ! regulation of binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904399 ! heparan sulfate binding +relationship: regulates GO:1904399 ! heparan sulfate binding +created_by: bc +creation_date: 2017-01-23T13:25:30Z + +[Term] +id: GO:1905854 +name: negative regulation of heparan sulfate binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +synonym: "down regulation of heparan sulfate binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of heparan sulfate binding" EXACT [GOC:TermGenie] +synonym: "downregulation of heparan sulfate binding" EXACT [GOC:TermGenie] +synonym: "inhibition of heparan sulfate binding" NARROW [GOC:TermGenie] +is_a: GO:0051100 ! negative regulation of binding +is_a: GO:1905853 ! regulation of heparan sulfate binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904399 ! heparan sulfate binding +relationship: negatively_regulates GO:1904399 ! heparan sulfate binding +created_by: bc +creation_date: 2017-01-23T13:25:38Z + +[Term] +id: GO:1905855 +name: positive regulation of heparan sulfate binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heparan sulfate binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +synonym: "activation of heparan sulfate binding" NARROW [GOC:TermGenie] +synonym: "up regulation of heparan sulfate binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of heparan sulfate binding" EXACT [GOC:TermGenie] +synonym: "upregulation of heparan sulfate binding" EXACT [GOC:TermGenie] +is_a: GO:0051099 ! positive regulation of binding +is_a: GO:1905853 ! regulation of heparan sulfate binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904399 ! heparan sulfate binding +relationship: positively_regulates GO:1904399 ! heparan sulfate binding +created_by: bc +creation_date: 2017-01-23T13:25:47Z + +[Term] +id: GO:1905856 +name: negative regulation of pentose-phosphate shunt +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt." [GO_REF:0000058, GOC:TermGenie, PMID:19015259] +is_a: GO:0043456 ! regulation of pentose-phosphate shunt +is_a: GO:0045936 ! negative regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006098 ! pentose-phosphate shunt +relationship: negatively_regulates GO:0006098 ! pentose-phosphate shunt +created_by: vw +creation_date: 2017-01-23T14:00:18Z + +[Term] +id: GO:1905857 +name: positive regulation of pentose-phosphate shunt +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt." [GO_REF:0000058, GOC:TermGenie, PMID:19015259] +is_a: GO:0043456 ! regulation of pentose-phosphate shunt +is_a: GO:0045937 ! positive regulation of phosphate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006098 ! pentose-phosphate shunt +relationship: positively_regulates GO:0006098 ! pentose-phosphate shunt +created_by: vw +creation_date: 2017-01-23T14:00:26Z + +[Term] +id: GO:1905858 +name: regulation of heparan sulfate proteoglycan binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +synonym: "regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043395 ! heparan sulfate proteoglycan binding +relationship: regulates GO:0043395 ! heparan sulfate proteoglycan binding +created_by: bc +creation_date: 2017-01-23T14:25:10Z + +[Term] +id: GO:1905859 +name: negative regulation of heparan sulfate proteoglycan binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +synonym: "down regulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "down regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "down-regulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "down-regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "downregulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "downregulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "inhibition of heparan sulfate proteoglycan binding" NARROW [GOC:TermGenie] +synonym: "inhibition of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "negative regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:1905858 ! regulation of heparan sulfate proteoglycan binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043395 ! heparan sulfate proteoglycan binding +relationship: negatively_regulates GO:0043395 ! heparan sulfate proteoglycan binding +created_by: bc +creation_date: 2017-01-23T14:25:19Z + +[Term] +id: GO:1905860 +name: positive regulation of heparan sulfate proteoglycan binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7683668] +synonym: "activation of heparan sulfate proteoglycan binding" NARROW [GOC:TermGenie] +synonym: "activation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "positive regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "up regulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "up regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "up-regulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "up-regulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +synonym: "upregulation of heparan sulfate proteoglycan binding" EXACT [GOC:TermGenie] +synonym: "upregulation of heparin proteoglycan binding" RELATED [GOC:TermGenie] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:1905858 ! regulation of heparan sulfate proteoglycan binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043395 ! heparan sulfate proteoglycan binding +relationship: positively_regulates GO:0043395 ! heparan sulfate proteoglycan binding +created_by: bc +creation_date: 2017-01-23T14:25:27Z + +[Term] +id: GO:1905861 +name: intranuclear rod assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod." [GO_REF:0000079, GOC:TermGenie, PMID:28074884] +synonym: "intranuclear actin rod assembly" EXACT [GOC:TermGenie] +synonym: "intranuclear actin rod formation" EXACT [GOC:TermGenie] +synonym: "intranuclear rod formation" EXACT [GOC:TermGenie] +is_a: GO:0022607 ! cellular component assembly +is_a: GO:0097435 ! supramolecular fiber organization +created_by: dph +creation_date: 2017-01-23T17:59:27Z + +[Term] +id: GO:1905862 +name: ferroxidase complex +namespace: cellular_component +def: "A protein complex which is capable of ferroxidase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16522632] +comment: An example of this is FET3 in Saccharomyces cerevisiae (P38993) in PMID:16522632 (inferred from direct assay). +is_a: GO:1990204 ! oxidoreductase complex +created_by: bhm +creation_date: 2017-01-25T10:01:39Z + +[Term] +id: GO:1905863 +name: invadopodium organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium." [GOC:TermGenie, PMID:15684033] +is_a: GO:0120036 ! plasma membrane bounded cell projection organization +created_by: sl +creation_date: 2017-01-25T22:54:14Z + +[Term] +id: GO:1905864 +name: regulation of Atg1/ULK1 kinase complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." [GO_REF:0000058, GOC:autophagy, GOC:mf, GOC:TermGenie, PMID:26567215] +synonym: "regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +relationship: regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +created_by: pr +creation_date: 2017-01-26T13:23:26Z + +[Term] +id: GO:1905865 +name: negative regulation of Atg1/ULK1 kinase complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." [GO_REF:0000058, GOC:autophagy, GOC:mf, GOC:TermGenie, PMID:26567215] +synonym: "down regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "inhibition of ATG1 kinase complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1 kinase complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1-ATG13 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1-ATG13 complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1/ULK1 kinase complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1/ULK1 kinase complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1/ULK1 signaling complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ATG1/ULK1 signaling complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of Atg1p signalling complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of Atg1p signalling complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1 signaling complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1 signaling complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1-ATG13-FIP200 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1-ATG13-FIP200 complex formation" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1-ATG13-RB1CC1 complex assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of ULK1-ATG13-RB1CC1 complex formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "negative regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:1905864 ! regulation of Atg1/ULK1 kinase complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +relationship: negatively_regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +created_by: pr +creation_date: 2017-01-26T13:23:35Z + +[Term] +id: GO:1905866 +name: positive regulation of Atg1/ULK1 kinase complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly." [GO_REF:0000058, GOC:autophagy, GOC:mf, GOC:TermGenie, PMID:26567215] +synonym: "activation of ATG1 kinase complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ATG1 kinase complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ATG1-ATG13 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ATG1-ATG13 complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ATG1/ULK1 kinase complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ATG1/ULK1 kinase complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ATG1/ULK1 signaling complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ATG1/ULK1 signaling complex formation" NARROW [GOC:TermGenie] +synonym: "activation of Atg1p signalling complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of Atg1p signalling complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ULK1 signaling complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ULK1 signaling complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ULK1-ATG13-FIP200 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ULK1-ATG13-FIP200 complex formation" NARROW [GOC:TermGenie] +synonym: "activation of ULK1-ATG13-RB1CC1 complex assembly" NARROW [GOC:TermGenie] +synonym: "activation of ULK1-ATG13-RB1CC1 complex formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "positive regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1-ATG13 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1-ATG13 complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1/ULK1 kinase complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1/ULK1 kinase complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1/ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ATG1/ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of Atg1p signalling complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of Atg1p signalling complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1 signaling complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1 signaling complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1-ATG13-FIP200 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1-ATG13-FIP200 complex formation" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1-ATG13-RB1CC1 complex assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of ULK1-ATG13-RB1CC1 complex formation" EXACT [GOC:TermGenie] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:1905864 ! regulation of Atg1/ULK1 kinase complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +relationship: positively_regulates GO:1904745 ! Atg1/ULK1 kinase complex assembly +created_by: pr +creation_date: 2017-01-26T13:23:44Z + +[Term] +id: GO:1905867 +name: epididymis development +namespace: biological_process +def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089] +synonym: "epididymus development" EXACT [GOC:TermGenie] +is_a: GO:0035295 ! tube development +is_a: GO:0048608 ! reproductive structure development +created_by: sl +creation_date: 2017-01-27T00:00:33Z + +[Term] +id: GO:1905868 +name: regulation of 3'-UTR-mediated mRNA stabilization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +synonym: "regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +is_a: GO:0043488 ! regulation of mRNA stability +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +relationship: regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +created_by: rz +creation_date: 2017-01-27T11:51:37Z + +[Term] +id: GO:1905869 +name: negative regulation of 3'-UTR-mediated mRNA stabilization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +synonym: "down regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "down regulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "down-regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "down-regulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "downregulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "downregulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "inhibition of 3'-untranslated region-mediated mRNA stabilization" NARROW [GOC:TermGenie] +synonym: "inhibition of 3'-UTR-mediated mRNA stabilization" NARROW [GOC:TermGenie] +synonym: "negative regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +is_a: GO:1905868 ! regulation of 3'-UTR-mediated mRNA stabilization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +relationship: negatively_regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +created_by: rz +creation_date: 2017-01-27T11:51:46Z + +[Term] +id: GO:1905870 +name: positive regulation of 3'-UTR-mediated mRNA stabilization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +synonym: "activation of 3'-untranslated region-mediated mRNA stabilization" NARROW [GOC:TermGenie] +synonym: "activation of 3'-UTR-mediated mRNA stabilization" NARROW [GOC:TermGenie] +synonym: "positive regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "up regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "up regulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "up-regulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "up-regulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "upregulation of 3'-untranslated region-mediated mRNA stabilization" EXACT [GOC:TermGenie] +synonym: "upregulation of 3'-UTR-mediated mRNA stabilization" EXACT [GOC:TermGenie] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:1905868 ! regulation of 3'-UTR-mediated mRNA stabilization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +relationship: positively_regulates GO:0070935 ! 3'-UTR-mediated mRNA stabilization +created_by: rz +creation_date: 2017-01-27T11:51:55Z + +[Term] +id: GO:1905871 +name: regulation of protein localization to cell leading edge +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] +synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902463 ! protein localization to cell leading edge +relationship: regulates GO:1902463 ! protein localization to cell leading edge +created_by: sl +creation_date: 2017-01-27T19:34:55Z + +[Term] +id: GO:1905872 +name: negative regulation of protein localization to cell leading edge +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] +synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +synonym: "inhibition of protein localisation in cell leading edge" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localisation to cell leading edge" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization in cell leading edge" NARROW [GOC:TermGenie] +synonym: "inhibition of protein localization to cell leading edge" NARROW [GOC:TermGenie] +synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:1905871 ! regulation of protein localization to cell leading edge +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1902463 ! protein localization to cell leading edge +relationship: negatively_regulates GO:1902463 ! protein localization to cell leading edge +created_by: sl +creation_date: 2017-01-27T19:35:04Z + +[Term] +id: GO:1905873 +name: positive regulation of protein localization to cell leading edge +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] +synonym: "activation of protein localisation in cell leading edge" NARROW [GOC:TermGenie] +synonym: "activation of protein localisation to cell leading edge" NARROW [GOC:TermGenie] +synonym: "activation of protein localization in cell leading edge" NARROW [GOC:TermGenie] +synonym: "activation of protein localization to cell leading edge" NARROW [GOC:TermGenie] +synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] +synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:1905871 ! regulation of protein localization to cell leading edge +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902463 ! protein localization to cell leading edge +relationship: positively_regulates GO:1902463 ! protein localization to cell leading edge +created_by: sl +creation_date: 2017-01-27T19:35:13Z + +[Term] +id: GO:1905874 +name: regulation of postsynaptic density organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of postsynaptic density organization." [GO_REF:0000058, GOC:TermGenie, PMID:21887379] +synonym: "regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "regulation of PSD organization" EXACT [GOC:TermGenie] +is_a: GO:0033043 ! regulation of organelle organization +is_a: GO:0099175 ! regulation of postsynapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097106 ! postsynaptic density organization +relationship: regulates GO:0097106 ! postsynaptic density organization +created_by: sl +creation_date: 2017-01-27T19:53:32Z + +[Term] +id: GO:1905875 +name: negative regulation of postsynaptic density organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization." [GO_REF:0000058, GOC:TermGenie, PMID:21887379] +synonym: "down regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "down regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "down regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "down regulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "down regulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "down-regulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "downregulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "downregulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "downregulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "downregulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "downregulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "inhibition of post synaptic density organization" NARROW [GOC:TermGenie] +synonym: "inhibition of post-synaptic density organization" NARROW [GOC:TermGenie] +synonym: "inhibition of postsynaptic density organisation" NARROW [GOC:TermGenie] +synonym: "inhibition of postsynaptic density organization" NARROW [GOC:TermGenie] +synonym: "inhibition of PSD organization" NARROW [GOC:TermGenie] +synonym: "negative regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "negative regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "negative regulation of PSD organization" EXACT [GOC:TermGenie] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:1905809 ! negative regulation of synapse organization +is_a: GO:1905874 ! regulation of postsynaptic density organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097106 ! postsynaptic density organization +relationship: negatively_regulates GO:0097106 ! postsynaptic density organization +created_by: sl +creation_date: 2017-01-27T19:53:41Z + +[Term] +id: GO:1905876 +name: positive regulation of postsynaptic density organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of postsynaptic density organization." [GO_REF:0000058, GOC:TermGenie, PMID:21887379] +synonym: "activation of post synaptic density organization" NARROW [GOC:TermGenie] +synonym: "activation of post-synaptic density organization" NARROW [GOC:TermGenie] +synonym: "activation of postsynaptic density organisation" NARROW [GOC:TermGenie] +synonym: "activation of postsynaptic density organization" NARROW [GOC:TermGenie] +synonym: "activation of PSD organization" NARROW [GOC:TermGenie] +synonym: "positive regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "positive regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "positive regulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "up regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "up regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "up regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "up regulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "up regulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "up-regulation of PSD organization" EXACT [GOC:TermGenie] +synonym: "upregulation of post synaptic density organization" EXACT [GOC:TermGenie] +synonym: "upregulation of post-synaptic density organization" EXACT [GOC:TermGenie] +synonym: "upregulation of postsynaptic density organisation" EXACT [GOC:TermGenie] +synonym: "upregulation of postsynaptic density organization" EXACT [GOC:TermGenie] +synonym: "upregulation of PSD organization" EXACT [GOC:TermGenie] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:1905874 ! regulation of postsynaptic density organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097106 ! postsynaptic density organization +relationship: positively_regulates GO:0097106 ! postsynaptic density organization +created_by: sl +creation_date: 2017-01-27T19:53:50Z + +[Term] +id: GO:1905877 +name: invadopodium assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form an invadopodium." [GO_REF:0000079, GOC:TermGenie, PMID:15684033] +synonym: "invadopodium formation" EXACT [GOC:TermGenie] +is_a: GO:0120031 ! plasma membrane bounded cell projection assembly +is_a: GO:1905863 ! invadopodium organization +created_by: sl +creation_date: 2017-01-27T20:44:07Z + +[Term] +id: GO:1905878 +name: invadopodium disassembly +namespace: biological_process +def: "The disaggregation of an invadopodium into its constituent components." [GO_REF:0000079, GOC:TermGenie, PMID:15684033] +is_a: GO:0022411 ! cellular component disassembly +is_a: GO:1905863 ! invadopodium organization +created_by: sl +creation_date: 2017-01-27T20:44:16Z + +[Term] +id: GO:1905879 +name: regulation of oogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +synonym: "regulation of ovum development" EXACT [GOC:TermGenie] +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:0060284 ! regulation of cell development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048477 ! oogenesis +relationship: regulates GO:0048477 ! oogenesis +created_by: hbye +creation_date: 2017-01-31T09:31:05Z + +[Term] +id: GO:1905880 +name: negative regulation of oogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "down regulation of ovum development" EXACT [GOC:TermGenie] +synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie] +synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of ovum development" EXACT [GOC:TermGenie] +synonym: "inhibition of oogenesis" NARROW [GOC:TermGenie] +synonym: "inhibition of ovum development" NARROW [GOC:TermGenie] +synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905879 ! regulation of oogenesis +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048477 ! oogenesis +relationship: negatively_regulates GO:0048477 ! oogenesis +created_by: hbye +creation_date: 2017-01-31T09:31:15Z + +[Term] +id: GO:1905881 +name: positive regulation of oogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +synonym: "activation of oogenesis" NARROW [GOC:TermGenie] +synonym: "activation of ovum development" NARROW [GOC:TermGenie] +synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie] +synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of ovum development" EXACT [GOC:TermGenie] +synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie] +synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of ovum development" EXACT [GOC:TermGenie] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905879 ! regulation of oogenesis +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048477 ! oogenesis +relationship: positively_regulates GO:0048477 ! oogenesis +created_by: hbye +creation_date: 2017-01-31T09:31:23Z + +[Term] +id: GO:1905882 +name: obsolete other organism cell wall +namespace: cellular_component +def: "OBSOLETE. Any cell wall that is part of a other organism." [GO_REF:0000064, GOC:TermGenie, PMID:12438152] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: pga +creation_date: 2017-01-31T10:57:28Z + +[Term] +id: GO:1905883 +name: regulation of triglyceride transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of triglyceride transport." [GO_REF:0000058, GOC:TermGenie, PMID:25849533] +synonym: "regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +is_a: GO:1901506 ! regulation of acylglycerol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034197 ! triglyceride transport +relationship: regulates GO:0034197 ! triglyceride transport +created_by: rz +creation_date: 2017-01-31T11:32:29Z + +[Term] +id: GO:1905884 +name: negative regulation of triglyceride transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport." [GO_REF:0000058, GOC:TermGenie, PMID:25849533] +synonym: "down regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "down regulation of triglyceride transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "down-regulation of triglyceride transport" EXACT [GOC:TermGenie] +synonym: "downregulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "downregulation of triglyceride transport" EXACT [GOC:TermGenie] +synonym: "inhibition of triacylglycerol transport" NARROW [GOC:TermGenie] +synonym: "inhibition of triglyceride transport" NARROW [GOC:TermGenie] +synonym: "negative regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +is_a: GO:1901507 ! negative regulation of acylglycerol transport +is_a: GO:1905883 ! regulation of triglyceride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034197 ! triglyceride transport +relationship: negatively_regulates GO:0034197 ! triglyceride transport +created_by: rz +creation_date: 2017-01-31T11:32:39Z + +[Term] +id: GO:1905885 +name: positive regulation of triglyceride transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of triglyceride transport." [GO_REF:0000058, GOC:TermGenie, PMID:25849533] +synonym: "activation of triacylglycerol transport" NARROW [GOC:TermGenie] +synonym: "activation of triglyceride transport" NARROW [GOC:TermGenie] +synonym: "positive regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "up regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "up regulation of triglyceride transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "up-regulation of triglyceride transport" EXACT [GOC:TermGenie] +synonym: "upregulation of triacylglycerol transport" EXACT [GOC:TermGenie] +synonym: "upregulation of triglyceride transport" EXACT [GOC:TermGenie] +is_a: GO:1901508 ! positive regulation of acylglycerol transport +is_a: GO:1905883 ! regulation of triglyceride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034197 ! triglyceride transport +relationship: positively_regulates GO:0034197 ! triglyceride transport +created_by: rz +creation_date: 2017-01-31T11:32:47Z + +[Term] +id: GO:1905886 +name: chromatin remodeling involved in meiosis I +namespace: biological_process +def: "Any chromatin remodeling that is involved in meiosis I." [GO_REF:0000060, GOC:TermGenie, PMID:19139281, PMID:25934010, PMID:9106659] +synonym: "chromatin modeling involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "chromatin modelling involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "chromatin remodelling involved in meiosis I" EXACT [GOC:TermGenie] +synonym: "meiosis-specific chromatin remodeling" EXACT [PMID:19139281] +is_a: GO:0006338 ! chromatin remodeling +is_a: GO:0061982 ! meiosis I cell cycle process +created_by: mah +creation_date: 2017-01-31T14:29:00Z + +[Term] +id: GO:1905887 +name: autoinducer AI-2 transmembrane transport +namespace: biological_process +def: "The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing." [GO_REF:0000069, GOC:TermGenie, PMID:15601708] +synonym: "(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport" EXACT [PMID:15601708] +synonym: "AI-2 transmembrane transport" EXACT [PMID:15601708] +synonym: "autoinducer 2 transmembrane transport" EXACT [PMID:15601708] +is_a: GO:0015791 ! polyol transport +is_a: GO:0055085 ! transmembrane transport +created_by: dos +creation_date: 2017-01-31T14:34:50Z + +[Term] +id: GO:1905888 +name: negative regulation of cellular response to very-low-density lipoprotein particle stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7592957] +synonym: "down regulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "down regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to very-low-density lipoprotein particle stimulus" NARROW [GOC:TermGenie] +synonym: "inhibition of cellular response to VLDL particle stimulus" NARROW [GOC:TermGenie] +synonym: "negative regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905890 ! regulation of cellular response to very-low-density lipoprotein particle stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +relationship: negatively_regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +created_by: bc +creation_date: 2017-02-01T10:09:25Z + +[Term] +id: GO:1905889 +name: positive regulation of cellular response to very-low-density lipoprotein particle stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7592957] +synonym: "activation of cellular response to very-low-density lipoprotein particle stimulus" NARROW [GOC:TermGenie] +synonym: "activation of cellular response to VLDL particle stimulus" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to very-low-density lipoprotein particle stimulus" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905890 ! regulation of cellular response to very-low-density lipoprotein particle stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +relationship: positively_regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +created_by: bc +creation_date: 2017-02-01T10:09:34Z + +[Term] +id: GO:1905890 +name: regulation of cellular response to very-low-density lipoprotein particle stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:7592957] +synonym: "regulation of cellular response to VLDL particle stimulus" EXACT [GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +relationship: regulates GO:0090731 ! cellular response to very-low-density lipoprotein particle stimulus +created_by: bc +creation_date: 2017-02-01T10:09:16Z + +[Term] +id: GO:1905891 +name: regulation of cellular response to thapsigargin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to thapsigargin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904579 ! cellular response to thapsigargin +relationship: regulates GO:1904579 ! cellular response to thapsigargin +created_by: bc +creation_date: 2017-02-01T11:36:07Z + +[Term] +id: GO:1905892 +name: negative regulation of cellular response to thapsigargin +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "down regulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to thapsigargin" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905891 ! regulation of cellular response to thapsigargin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904579 ! cellular response to thapsigargin +relationship: negatively_regulates GO:1904579 ! cellular response to thapsigargin +created_by: bc +creation_date: 2017-02-01T11:36:15Z + +[Term] +id: GO:1905893 +name: positive regulation of cellular response to thapsigargin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "activation of cellular response to thapsigargin" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to thapsigargin" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905891 ! regulation of cellular response to thapsigargin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904579 ! cellular response to thapsigargin +relationship: positively_regulates GO:1904579 ! cellular response to thapsigargin +created_by: bc +creation_date: 2017-02-01T11:36:24Z + +[Term] +id: GO:1905894 +name: regulation of cellular response to tunicamycin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to tunicamycin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1904577 ! cellular response to tunicamycin +relationship: regulates GO:1904577 ! cellular response to tunicamycin +created_by: bc +creation_date: 2017-02-01T11:36:34Z + +[Term] +id: GO:1905895 +name: negative regulation of cellular response to tunicamycin +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "down regulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to tunicamycin" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905894 ! regulation of cellular response to tunicamycin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1904577 ! cellular response to tunicamycin +relationship: negatively_regulates GO:1904577 ! cellular response to tunicamycin +created_by: bc +creation_date: 2017-02-01T11:36:42Z + +[Term] +id: GO:1905896 +name: positive regulation of cellular response to tunicamycin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "activation of cellular response to tunicamycin" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to tunicamycin" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905894 ! regulation of cellular response to tunicamycin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1904577 ! cellular response to tunicamycin +relationship: positively_regulates GO:1904577 ! cellular response to tunicamycin +created_by: bc +creation_date: 2017-02-01T11:36:51Z + +[Term] +id: GO:1905897 +name: regulation of response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "regulation of response to ER stress" EXACT [GOC:TermGenie] +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034976 ! response to endoplasmic reticulum stress +relationship: regulates GO:0034976 ! response to endoplasmic reticulum stress +created_by: bc +creation_date: 2017-02-01T11:42:55Z + +[Term] +id: GO:1905898 +name: positive regulation of response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:21803450] +synonym: "activation of cellular response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "activation of ER stress response" NARROW [GOC:TermGenie] +synonym: "activation of response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] +synonym: "activation of response to ER stress" NARROW [GOC:TermGenie] +synonym: "positive regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "positive regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "positive regulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "up regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "up regulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up regulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to ER stress" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of ER stress response" EXACT [GOC:TermGenie] +synonym: "upregulation of response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] +synonym: "upregulation of response to ER stress" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905897 ! regulation of response to endoplasmic reticulum stress +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034976 ! response to endoplasmic reticulum stress +relationship: positively_regulates GO:0034976 ! response to endoplasmic reticulum stress +created_by: bc +creation_date: 2017-02-01T11:43:03Z + +[Term] +id: GO:1905899 +name: regulation of smooth muscle tissue development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] +is_a: GO:1901861 ! regulation of muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048745 ! smooth muscle tissue development +relationship: regulates GO:0048745 ! smooth muscle tissue development +created_by: bhm +creation_date: 2017-02-01T14:31:16Z + +[Term] +id: GO:1905900 +name: negative regulation of smooth muscle tissue development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] +synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +synonym: "inhibition of smooth muscle tissue development" NARROW [GOC:TermGenie] +is_a: GO:1901862 ! negative regulation of muscle tissue development +is_a: GO:1905899 ! regulation of smooth muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048745 ! smooth muscle tissue development +relationship: negatively_regulates GO:0048745 ! smooth muscle tissue development +created_by: bhm +creation_date: 2017-02-01T14:31:24Z + +[Term] +id: GO:1905901 +name: positive regulation of smooth muscle tissue development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] +synonym: "activation of smooth muscle tissue development" NARROW [GOC:TermGenie] +synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] +is_a: GO:1901863 ! positive regulation of muscle tissue development +is_a: GO:1905899 ! regulation of smooth muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048745 ! smooth muscle tissue development +relationship: positively_regulates GO:0048745 ! smooth muscle tissue development +created_by: bhm +creation_date: 2017-02-01T14:31:33Z + +[Term] +id: GO:1905902 +name: regulation of mesoderm formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:2000380 ! regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001707 ! mesoderm formation +relationship: regulates GO:0001707 ! mesoderm formation +created_by: rph +creation_date: 2017-02-03T12:28:20Z + +[Term] +id: GO:1905903 +name: negative regulation of mesoderm formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] +synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie] +synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie] +synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie] +is_a: GO:1905902 ! regulation of mesoderm formation +is_a: GO:2000381 ! negative regulation of mesoderm development +is_a: GO:2000542 ! negative regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001707 ! mesoderm formation +relationship: negatively_regulates GO:0001707 ! mesoderm formation +created_by: rph +creation_date: 2017-02-03T12:28:29Z + +[Term] +id: GO:1905904 +name: positive regulation of mesoderm formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] +synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie] +synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie] +synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie] +is_a: GO:1905902 ! regulation of mesoderm formation +is_a: GO:2000382 ! positive regulation of mesoderm development +is_a: GO:2000543 ! positive regulation of gastrulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001707 ! mesoderm formation +relationship: positively_regulates GO:0001707 ! mesoderm formation +created_by: rph +creation_date: 2017-02-03T12:28:38Z + +[Term] +id: GO:1905905 +name: pharyngeal gland morphogenesis +namespace: biological_process +def: "The developmental process by which a pharyngeal gland is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:21868609] +synonym: "glandulae pharyngeae morphogenesis" RELATED [GOC:TermGenie] +synonym: "pharynx gland morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0022612 ! gland morphogenesis +created_by: rz +creation_date: 2017-02-03T14:39:10Z + +[Term] +id: GO:1905906 +name: regulation of amyloid fibril formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amyloid fibril formation." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:23106396] +comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896). +synonym: "regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "regulation of amyloid structure formation" RELATED [GOC:TermGenie] +is_a: GO:0051246 ! regulation of protein metabolic process +is_a: GO:1902903 ! regulation of supramolecular fiber organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990000 ! amyloid fibril formation +relationship: regulates GO:1990000 ! amyloid fibril formation +created_by: bc +creation_date: 2017-02-03T15:43:48Z + +[Term] +id: GO:1905907 +name: negative regulation of amyloid fibril formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:23106396] +comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896). +synonym: "down regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "down regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "down regulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "down-regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "down-regulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "downregulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "downregulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "downregulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "inhibition of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of amyloid fibril formation" NARROW [GOC:TermGenie] +synonym: "inhibition of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "inhibition of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "negative regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "negative regulation of amyloid structure formation" RELATED [GOC:TermGenie] +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:1902904 ! negative regulation of supramolecular fiber organization +is_a: GO:1905906 ! regulation of amyloid fibril formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990000 ! amyloid fibril formation +relationship: negatively_regulates GO:1990000 ! amyloid fibril formation +created_by: bc +creation_date: 2017-02-03T15:43:56Z + +[Term] +id: GO:1905908 +name: positive regulation of amyloid fibril formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amyloid fibril formation." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:23106396] +comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896). +synonym: "activation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "activation of amyloid fibril formation" NARROW [GOC:TermGenie] +synonym: "activation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "activation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "positive regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "positive regulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "up regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "up regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "up regulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "up-regulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "up-regulation of amyloid structure formation" RELATED [GOC:TermGenie] +synonym: "upregulation of amyloid fibril assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of amyloid fibril formation" EXACT [GOC:TermGenie] +synonym: "upregulation of amyloid structure assembly" RELATED [GOC:TermGenie] +synonym: "upregulation of amyloid structure formation" RELATED [GOC:TermGenie] +is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:1902905 ! positive regulation of supramolecular fiber organization +is_a: GO:1905906 ! regulation of amyloid fibril formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990000 ! amyloid fibril formation +relationship: positively_regulates GO:1990000 ! amyloid fibril formation +created_by: bc +creation_date: 2017-02-03T15:44:05Z + +[Term] +id: GO:1905909 +name: regulation of dauer entry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dauer entry." [GO_REF:0000058, GOC:TermGenie, PMID:21531333] +synonym: "regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +is_a: GO:0061065 ! regulation of dauer larval development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043053 ! dauer entry +relationship: regulates GO:0043053 ! dauer entry +created_by: hbye +creation_date: 2017-02-06T15:34:01Z + +[Term] +id: GO:1905910 +name: negative regulation of dauer entry +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry." [GO_REF:0000058, GOC:TermGenie, PMID:21531333] +synonym: "down regulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "down regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "down-regulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "down-regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "downregulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "downregulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "inhibition of dauer entry" NARROW [GOC:TermGenie] +synonym: "inhibition of nematode entry into dormancy" NARROW [GOC:TermGenie] +synonym: "negative regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +is_a: GO:0061067 ! negative regulation of dauer larval development +is_a: GO:1905909 ! regulation of dauer entry +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043053 ! dauer entry +relationship: negatively_regulates GO:0043053 ! dauer entry +created_by: hbye +creation_date: 2017-02-06T15:34:11Z + +[Term] +id: GO:1905911 +name: positive regulation of dauer entry +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dauer entry." [GO_REF:0000058, GOC:TermGenie, PMID:21531333] +synonym: "activation of dauer entry" NARROW [GOC:TermGenie] +synonym: "activation of nematode entry into dormancy" NARROW [GOC:TermGenie] +synonym: "positive regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "up regulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "up regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "up-regulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "up-regulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +synonym: "upregulation of dauer entry" EXACT [GOC:TermGenie] +synonym: "upregulation of nematode entry into dormancy" EXACT [GOC:TermGenie] +is_a: GO:0061066 ! positive regulation of dauer larval development +is_a: GO:1905909 ! regulation of dauer entry +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043053 ! dauer entry +relationship: positively_regulates GO:0043053 ! dauer entry +created_by: hbye +creation_date: 2017-02-06T15:34:20Z + +[Term] +id: GO:1905912 +name: regulation of calcium ion export across plasma membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22362515] +synonym: "regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "regulation of calcium ion export from cell" EXACT [] +is_a: GO:1903169 ! regulation of calcium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990034 ! calcium ion export across plasma membrane +relationship: regulates GO:1990034 ! calcium ion export across plasma membrane +created_by: rph +creation_date: 2017-02-07T13:20:39Z + +[Term] +id: GO:1905913 +name: negative regulation of calcium ion export across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22362515] +synonym: "down regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "down regulation of calcium ion export from cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion export from cell" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion export from cell" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion efflux from cell" NARROW [GOC:TermGenie] +synonym: "inhibition of calcium ion export from cell" NARROW [GOC:TermGenie] +synonym: "negative regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "negative regulation of calcium ion export from cell" EXACT [] +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +is_a: GO:1905912 ! regulation of calcium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:1990034 ! calcium ion export across plasma membrane +relationship: negatively_regulates GO:1990034 ! calcium ion export across plasma membrane +created_by: rph +creation_date: 2017-02-07T13:20:48Z + +[Term] +id: GO:1905914 +name: positive regulation of calcium ion export across plasma membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22362515] +synonym: "activation of calcium ion efflux from cell" NARROW [GOC:TermGenie] +synonym: "activation of calcium ion export from cell" NARROW [GOC:TermGenie] +synonym: "positive regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "positive regulation of calcium ion export from cell" EXACT [] +synonym: "up regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "up regulation of calcium ion export from cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "up-regulation of calcium ion export from cell" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion efflux from cell" EXACT [GOC:TermGenie] +synonym: "upregulation of calcium ion export from cell" EXACT [GOC:TermGenie] +is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport +is_a: GO:1905912 ! regulation of calcium ion export across plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1990034 ! calcium ion export across plasma membrane +relationship: positively_regulates GO:1990034 ! calcium ion export across plasma membrane +created_by: rph +creation_date: 2017-02-07T13:20:56Z + +[Term] +id: GO:1905915 +name: regulation of cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1900239 ! regulation of phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0090679 ! cell differentiation involved in phenotypic switching +relationship: regulates GO:0090679 ! cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-08T12:23:14Z + +[Term] +id: GO:1905916 +name: negative regulation of cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "down regulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "downregulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "inhibition of cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:1900240 ! negative regulation of phenotypic switching +is_a: GO:1905915 ! regulation of cell differentiation involved in phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0090679 ! cell differentiation involved in phenotypic switching +relationship: negatively_regulates GO:0090679 ! cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-08T12:23:23Z + +[Term] +id: GO:1905917 +name: positive regulation of cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "activation of cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "up regulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "upregulation of cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1900241 ! positive regulation of phenotypic switching +is_a: GO:1905915 ! regulation of cell differentiation involved in phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0090679 ! cell differentiation involved in phenotypic switching +relationship: positively_regulates GO:0090679 ! cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-08T12:23:31Z + +[Term] +id: GO:1905918 +name: regulation of CoA-transferase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CoA-transferase activity." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0008410 ! CoA-transferase activity +relationship: regulates GO:0008410 ! CoA-transferase activity +created_by: bc +creation_date: 2017-02-08T13:00:48Z + +[Term] +id: GO:1905919 +name: negative regulation of CoA-transferase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +synonym: "down regulation of CoA-transferase activity" EXACT [GOC:TermGenie] +synonym: "down-regulation of CoA-transferase activity" EXACT [GOC:TermGenie] +synonym: "downregulation of CoA-transferase activity" EXACT [GOC:TermGenie] +synonym: "inhibition of CoA-transferase activity" NARROW [GOC:TermGenie] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:1905918 ! regulation of CoA-transferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0008410 ! CoA-transferase activity +relationship: negatively_regulates GO:0008410 ! CoA-transferase activity +created_by: bc +creation_date: 2017-02-08T13:00:56Z + +[Term] +id: GO:1905920 +name: positive regulation of CoA-transferase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CoA-transferase activity." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +synonym: "activation of CoA-transferase activity" NARROW [GOC:TermGenie] +synonym: "up regulation of CoA-transferase activity" EXACT [GOC:TermGenie] +synonym: "up-regulation of CoA-transferase activity" EXACT [GOC:TermGenie] +synonym: "upregulation of CoA-transferase activity" EXACT [GOC:TermGenie] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:1905918 ! regulation of CoA-transferase activity +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0008410 ! CoA-transferase activity +relationship: positively_regulates GO:0008410 ! CoA-transferase activity +created_by: bc +creation_date: 2017-02-08T13:01:04Z + +[Term] +id: GO:1905921 +name: regulation of acetylcholine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0060408 ! regulation of acetylcholine metabolic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0008292 ! acetylcholine biosynthetic process +relationship: regulates GO:0008292 ! acetylcholine biosynthetic process +created_by: bc +creation_date: 2017-02-08T13:08:30Z + +[Term] +id: GO:1905922 +name: negative regulation of acetylcholine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "inhibition of acetylcholine anabolism" NARROW [GOC:TermGenie] +synonym: "inhibition of acetylcholine biosynthesis" NARROW [GOC:TermGenie] +synonym: "inhibition of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "inhibition of acetylcholine formation" NARROW [GOC:TermGenie] +synonym: "inhibition of acetylcholine synthesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0060410 ! negative regulation of acetylcholine metabolic process +is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process +relationship: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process +created_by: bc +creation_date: 2017-02-08T13:08:39Z + +[Term] +id: GO:1905923 +name: positive regulation of acetylcholine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] +synonym: "activation of acetylcholine anabolism" NARROW [GOC:TermGenie] +synonym: "activation of acetylcholine biosynthesis" NARROW [GOC:TermGenie] +synonym: "activation of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] +synonym: "activation of acetylcholine formation" NARROW [GOC:TermGenie] +synonym: "activation of acetylcholine synthesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie] +synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process +is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0008292 ! acetylcholine biosynthetic process +relationship: positively_regulates GO:0008292 ! acetylcholine biosynthetic process +created_by: bc +creation_date: 2017-02-08T13:08:48Z + +[Term] +id: GO:1905924 +name: regulation of invadopodium assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of invadopodium assembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +synonym: "regulation of invadopodium formation" EXACT [GOC:TermGenie] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1905877 ! invadopodium assembly +relationship: regulates GO:1905877 ! invadopodium assembly +created_by: sl +creation_date: 2017-02-08T21:38:30Z + +[Term] +id: GO:1905925 +name: negative regulation of invadopodium assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +synonym: "down regulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "down regulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "down-regulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "downregulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "downregulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "inhibition of invadopodium assembly" NARROW [GOC:TermGenie] +synonym: "inhibition of invadopodium formation" NARROW [GOC:TermGenie] +synonym: "negative regulation of invadopodium formation" EXACT [GOC:TermGenie] +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:1905924 ! regulation of invadopodium assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1905877 ! invadopodium assembly +relationship: negatively_regulates GO:1905877 ! invadopodium assembly +created_by: sl +creation_date: 2017-02-08T21:38:39Z + +[Term] +id: GO:1905926 +name: positive regulation of invadopodium assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of invadopodium assembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +synonym: "activation of invadopodium assembly" NARROW [GOC:TermGenie] +synonym: "activation of invadopodium formation" NARROW [GOC:TermGenie] +synonym: "positive regulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "up regulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "up regulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "up-regulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of invadopodium formation" EXACT [GOC:TermGenie] +synonym: "upregulation of invadopodium assembly" EXACT [GOC:TermGenie] +synonym: "upregulation of invadopodium formation" EXACT [GOC:TermGenie] +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:1905924 ! regulation of invadopodium assembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1905877 ! invadopodium assembly +relationship: positively_regulates GO:1905877 ! invadopodium assembly +created_by: sl +creation_date: 2017-02-08T21:38:48Z + +[Term] +id: GO:1905927 +name: regulation of invadopodium disassembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of invadopodium disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1905878 ! invadopodium disassembly +relationship: regulates GO:1905878 ! invadopodium disassembly +created_by: sl +creation_date: 2017-02-08T21:38:57Z + +[Term] +id: GO:1905928 +name: negative regulation of invadopodium disassembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +synonym: "down regulation of invadopodium disassembly" EXACT [GOC:TermGenie] +synonym: "down-regulation of invadopodium disassembly" EXACT [GOC:TermGenie] +synonym: "downregulation of invadopodium disassembly" EXACT [GOC:TermGenie] +synonym: "inhibition of invadopodium disassembly" NARROW [GOC:TermGenie] +is_a: GO:0031345 ! negative regulation of cell projection organization +is_a: GO:1905927 ! regulation of invadopodium disassembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1905878 ! invadopodium disassembly +relationship: negatively_regulates GO:1905878 ! invadopodium disassembly +created_by: sl +creation_date: 2017-02-08T21:39:05Z + +[Term] +id: GO:1905929 +name: positive regulation of invadopodium disassembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of invadopodium disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:15684033] +synonym: "activation of invadopodium disassembly" NARROW [GOC:TermGenie] +synonym: "up regulation of invadopodium disassembly" EXACT [GOC:TermGenie] +synonym: "up-regulation of invadopodium disassembly" EXACT [GOC:TermGenie] +synonym: "upregulation of invadopodium disassembly" EXACT [GOC:TermGenie] +is_a: GO:0031346 ! positive regulation of cell projection organization +is_a: GO:1905927 ! regulation of invadopodium disassembly +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1905878 ! invadopodium disassembly +relationship: positively_regulates GO:1905878 ! invadopodium disassembly +created_by: sl +creation_date: 2017-02-08T21:39:14Z + +[Term] +id: GO:1905930 +name: regulation of vascular smooth muscle cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:1905063 ! regulation of vascular smooth muscle cell differentiation +is_a: GO:1905915 ! regulation of cell differentiation involved in phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +relationship: regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-09T09:20:59Z + +[Term] +id: GO:1905931 +name: negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "down-regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "down-regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "downregulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "downregulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "inhibition of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "inhibition of VSMC differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "negative regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "negative regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:1905064 ! negative regulation of vascular smooth muscle cell differentiation +is_a: GO:1905916 ! negative regulation of cell differentiation involved in phenotypic switching +is_a: GO:1905930 ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +relationship: negatively_regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-09T09:21:08Z + +[Term] +id: GO:1905932 +name: positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25089138] +synonym: "activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "activation of vascular smooth muscle cell differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "activation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "activation of VSMC differentiation involved in phenotypic switching" NARROW [GOC:TermGenie] +synonym: "positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "positive regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "positive regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "up-regulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "up-regulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +synonym: "upregulation of VSMC differentiation involved in phenotypic dimorphism" RELATED [GOC:TermGenie] +synonym: "upregulation of VSMC differentiation involved in phenotypic switching" EXACT [GOC:TermGenie] +is_a: GO:1905065 ! positive regulation of vascular smooth muscle cell differentiation +is_a: GO:1905917 ! positive regulation of cell differentiation involved in phenotypic switching +is_a: GO:1905930 ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +relationship: positively_regulates GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching +created_by: rph +creation_date: 2017-02-09T09:21:17Z + +[Term] +id: GO:1905933 +name: regulation of cell fate determination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell fate determination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25793578] +is_a: GO:0010453 ! regulation of cell fate commitment +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0001709 ! cell fate determination +relationship: regulates GO:0001709 ! cell fate determination +created_by: bhm +creation_date: 2017-02-09T11:25:21Z + +[Term] +id: GO:1905934 +name: negative regulation of cell fate determination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25793578] +synonym: "down regulation of cell fate determination" EXACT [GOC:TermGenie] +synonym: "down-regulation of cell fate determination" EXACT [GOC:TermGenie] +synonym: "downregulation of cell fate determination" EXACT [GOC:TermGenie] +synonym: "inhibition of cell fate determination" NARROW [GOC:TermGenie] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:1905933 ! regulation of cell fate determination +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0001709 ! cell fate determination +relationship: negatively_regulates GO:0001709 ! cell fate determination +created_by: bhm +creation_date: 2017-02-09T11:25:30Z + +[Term] +id: GO:1905935 +name: positive regulation of cell fate determination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell fate determination." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25793578] +synonym: "activation of cell fate determination" NARROW [GOC:TermGenie] +synonym: "up regulation of cell fate determination" EXACT [GOC:TermGenie] +synonym: "up-regulation of cell fate determination" EXACT [GOC:TermGenie] +synonym: "upregulation of cell fate determination" EXACT [GOC:TermGenie] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:1905933 ! regulation of cell fate determination +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0001709 ! cell fate determination +relationship: positively_regulates GO:0001709 ! cell fate determination +created_by: bhm +creation_date: 2017-02-09T11:25:38Z + +[Term] +id: GO:1905936 +name: regulation of germ cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:0043900 ! regulation of multi-organism process +is_a: GO:0051239 ! regulation of multicellular organismal process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0036093 ! germ cell proliferation +relationship: regulates GO:0036093 ! germ cell proliferation +created_by: hbye +creation_date: 2017-02-09T14:51:31Z + +[Term] +id: GO:1905937 +name: negative regulation of germ cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie] +synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie] +synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie] +synonym: "inhibition of germ cell proliferation" NARROW [GOC:TermGenie] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0043901 ! negative regulation of multi-organism process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905936 ! regulation of germ cell proliferation +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0036093 ! germ cell proliferation +relationship: negatively_regulates GO:0036093 ! germ cell proliferation +created_by: hbye +creation_date: 2017-02-09T14:51:41Z + +[Term] +id: GO:1905938 +name: positive regulation of germ cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +synonym: "activation of germ cell proliferation" NARROW [GOC:TermGenie] +synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie] +synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie] +synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0043902 ! positive regulation of multi-organism process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905936 ! regulation of germ cell proliferation +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0036093 ! germ cell proliferation +relationship: positively_regulates GO:0036093 ! germ cell proliferation +created_by: hbye +creation_date: 2017-02-09T14:51:51Z + +[Term] +id: GO:1905939 +name: regulation of gonad development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie] +is_a: GO:2000026 ! regulation of multicellular organismal development +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0008406 ! gonad development +relationship: regulates GO:0008406 ! gonad development +created_by: hbye +creation_date: 2017-02-09T17:01:50Z + +[Term] +id: GO:1905940 +name: negative regulation of gonad development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +synonym: "down regulation of gonad development" EXACT [GOC:TermGenie] +synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie] +synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of gonad development" EXACT [GOC:TermGenie] +synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of gonad development" NARROW [GOC:TermGenie] +synonym: "inhibition of gonadogenesis" NARROW [GOC:TermGenie] +synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905939 ! regulation of gonad development +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0008406 ! gonad development +relationship: negatively_regulates GO:0008406 ! gonad development +created_by: hbye +creation_date: 2017-02-09T17:01:59Z + +[Term] +id: GO:1905941 +name: positive regulation of gonad development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] +synonym: "activation of gonad development" NARROW [GOC:TermGenie] +synonym: "activation of gonadogenesis" NARROW [GOC:TermGenie] +synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "up regulation of gonad development" EXACT [GOC:TermGenie] +synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie] +synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of gonad development" EXACT [GOC:TermGenie] +synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905939 ! regulation of gonad development +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0008406 ! gonad development +relationship: positively_regulates GO:0008406 ! gonad development +created_by: hbye +creation_date: 2017-02-09T17:02:08Z + +[Term] +id: GO:1905942 +name: regulation of formation of growth cone in injured axon +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +is_a: GO:0048686 ! regulation of sprouting of injured axon +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0048689 ! formation of growth cone in injured axon +relationship: regulates GO:0048689 ! formation of growth cone in injured axon +created_by: rz +creation_date: 2017-02-13T09:09:05Z + +[Term] +id: GO:1905943 +name: negative regulation of formation of growth cone in injured axon +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +synonym: "down regulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +synonym: "down-regulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +synonym: "downregulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +synonym: "inhibition of formation of growth cone in injured axon" NARROW [GOC:TermGenie] +is_a: GO:0048688 ! negative regulation of sprouting of injured axon +is_a: GO:1905942 ! regulation of formation of growth cone in injured axon +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0048689 ! formation of growth cone in injured axon +relationship: negatively_regulates GO:0048689 ! formation of growth cone in injured axon +created_by: rz +creation_date: 2017-02-13T09:09:13Z + +[Term] +id: GO:1905944 +name: positive regulation of formation of growth cone in injured axon +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon." [GO_REF:0000058, GOC:TermGenie, PMID:19737525] +synonym: "activation of formation of growth cone in injured axon" NARROW [GOC:TermGenie] +synonym: "up regulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +synonym: "up-regulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +synonym: "upregulation of formation of growth cone in injured axon" EXACT [GOC:TermGenie] +is_a: GO:0048687 ! positive regulation of sprouting of injured axon +is_a: GO:1905942 ! regulation of formation of growth cone in injured axon +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0048689 ! formation of growth cone in injured axon +relationship: positively_regulates GO:0048689 ! formation of growth cone in injured axon +created_by: rz +creation_date: 2017-02-13T09:09:21Z + +[Term] +id: GO:1905945 +name: regulation of response to calcium ion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to calcium ion." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:11404397] +synonym: "regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0051592 ! response to calcium ion +relationship: regulates GO:0051592 ! response to calcium ion +created_by: bc +creation_date: 2017-02-13T10:56:34Z + +[Term] +id: GO:1905946 +name: negative regulation of response to calcium ion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:11404397] +synonym: "down regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "down regulation of response to calcium ion" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "down-regulation of response to calcium ion" EXACT [GOC:TermGenie] +synonym: "downregulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "downregulation of response to calcium ion" EXACT [GOC:TermGenie] +synonym: "inhibition of response to Ca2+ ion" NARROW [GOC:TermGenie] +synonym: "inhibition of response to calcium ion" NARROW [GOC:TermGenie] +synonym: "negative regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:1905945 ! regulation of response to calcium ion +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0051592 ! response to calcium ion +relationship: negatively_regulates GO:0051592 ! response to calcium ion +created_by: bc +creation_date: 2017-02-13T10:56:41Z + +[Term] +id: GO:1905947 +name: positive regulation of response to calcium ion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to calcium ion." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:11404397] +synonym: "activation of response to Ca2+ ion" NARROW [GOC:TermGenie] +synonym: "activation of response to calcium ion" NARROW [GOC:TermGenie] +synonym: "positive regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "up regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "up regulation of response to calcium ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "up-regulation of response to calcium ion" EXACT [GOC:TermGenie] +synonym: "upregulation of response to Ca2+ ion" EXACT [GOC:TermGenie] +synonym: "upregulation of response to calcium ion" EXACT [GOC:TermGenie] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:1905945 ! regulation of response to calcium ion +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0051592 ! response to calcium ion +relationship: positively_regulates GO:0051592 ! response to calcium ion +created_by: bc +creation_date: 2017-02-13T10:56:49Z + +[Term] +id: GO:1905948 +name: ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity +namespace: molecular_function +def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out)." [GO_REF:0000070, GOC:TermGenie, PMID:18310115] +synonym: "3',5'-cyclic GMP transmembrane-transporting ATPase activity" EXACT [] +synonym: "ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity" EXACT [] +synonym: "ATPase-coupled cGMP transmembrane transporter activity" EXACT [] +is_a: GO:0001409 ! guanine nucleotide transmembrane transporter activity +is_a: GO:0005346 ! purine ribonucleotide transmembrane transporter activity +is_a: GO:0008514 ! organic anion transmembrane transporter activity +is_a: GO:0042625 ! ATPase-coupled ion transmembrane transporter activity +created_by: ha +creation_date: 2017-02-16T15:54:51Z + +[Term] +id: GO:1905949 +name: negative regulation of calcium ion import across plasma membrane +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17640527] +comment: An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay). +synonym: "down regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "down-regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "downregulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +synonym: "inhibition of calcium ion import across plasma membrane" NARROW [GOC:TermGenie] +is_a: GO:0010523 ! negative regulation of calcium ion transport into cytosol +is_a: GO:0090281 ! negative regulation of calcium ion import +is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport +is_a: GO:1905664 ! regulation of calcium ion import across plasma membrane +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0098703 ! calcium ion import across plasma membrane +relationship: negatively_regulates GO:0098703 ! calcium ion import across plasma membrane +created_by: bhm +creation_date: 2017-02-17T09:42:30Z + +[Term] +id: GO:1905951 +name: mitochondrion DNA recombination +namespace: biological_process +def: "Any DNA recombination that takes place in mitochondrion." [GO_REF:0000062, GOC:TermGenie, PMID:8087883] +synonym: "DNA recombination in mitochondria" EXACT [GOC:TermGenie] +is_a: GO:0006310 ! DNA recombination +is_a: GO:0032042 ! mitochondrial DNA metabolic process +intersection_of: GO:0006310 ! DNA recombination +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: vw +creation_date: 2017-02-19T10:48:17Z + +[Term] +id: GO:1905952 +name: regulation of lipid localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] +synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie] +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0010876 ! lipid localization +relationship: regulates GO:0010876 ! lipid localization +created_by: rz +creation_date: 2017-02-21T12:12:22Z + +[Term] +id: GO:1905953 +name: negative regulation of lipid localization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] +synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie] +synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie] +synonym: "inhibition of lipid localisation" NARROW [GOC:TermGenie] +synonym: "inhibition of lipid localization" NARROW [GOC:TermGenie] +synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:1905952 ! regulation of lipid localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0010876 ! lipid localization +relationship: negatively_regulates GO:0010876 ! lipid localization +created_by: rz +creation_date: 2017-02-21T12:12:41Z + +[Term] +id: GO:1905954 +name: positive regulation of lipid localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] +synonym: "activation of lipid localisation" NARROW [GOC:TermGenie] +synonym: "activation of lipid localization" NARROW [GOC:TermGenie] +synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie] +synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie] +synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:1905952 ! regulation of lipid localization +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0010876 ! lipid localization +relationship: positively_regulates GO:0010876 ! lipid localization +created_by: rz +creation_date: 2017-02-21T12:12:49Z + +[Term] +id: GO:1905955 +name: negative regulation of endothelial tube morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] +synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +synonym: "inhibition of endothelial tube morphogenesis" NARROW [GOC:TermGenie] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1901509 ! regulation of endothelial tube morphogenesis +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0061154 ! endothelial tube morphogenesis +relationship: negatively_regulates GO:0061154 ! endothelial tube morphogenesis +created_by: rph +creation_date: 2017-02-21T15:17:31Z + +[Term] +id: GO:1905956 +name: positive regulation of endothelial tube morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] +synonym: "activation of endothelial tube morphogenesis" NARROW [GOC:TermGenie] +synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1901509 ! regulation of endothelial tube morphogenesis +is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0061154 ! endothelial tube morphogenesis +relationship: positively_regulates GO:0061154 ! endothelial tube morphogenesis +created_by: rph +creation_date: 2017-02-21T15:17:39Z + +[Term] +id: GO:1905957 +name: regulation of cellular response to alcohol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:1901419 ! regulation of response to alcohol +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0097306 ! cellular response to alcohol +relationship: regulates GO:0097306 ! cellular response to alcohol +created_by: hbye +creation_date: 2017-02-22T12:03:00Z + +[Term] +id: GO:1905958 +name: negative regulation of cellular response to alcohol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +synonym: "down regulation of cellular response to alcohol" EXACT [GOC:TermGenie] +synonym: "down-regulation of cellular response to alcohol" EXACT [GOC:TermGenie] +synonym: "downregulation of cellular response to alcohol" EXACT [GOC:TermGenie] +synonym: "inhibition of cellular response to alcohol" NARROW [GOC:TermGenie] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:1901420 ! negative regulation of response to alcohol +is_a: GO:1905957 ! regulation of cellular response to alcohol +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0097306 ! cellular response to alcohol +relationship: negatively_regulates GO:0097306 ! cellular response to alcohol +created_by: hbye +creation_date: 2017-02-22T12:03:08Z + +[Term] +id: GO:1905959 +name: positive regulation of cellular response to alcohol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to alcohol." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] +synonym: "activation of cellular response to alcohol" NARROW [GOC:TermGenie] +synonym: "up regulation of cellular response to alcohol" EXACT [GOC:TermGenie] +synonym: "up-regulation of cellular response to alcohol" EXACT [GOC:TermGenie] +synonym: "upregulation of cellular response to alcohol" EXACT [GOC:TermGenie] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:1901421 ! positive regulation of response to alcohol +is_a: GO:1905957 ! regulation of cellular response to alcohol +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0097306 ! cellular response to alcohol +relationship: positively_regulates GO:0097306 ! cellular response to alcohol +created_by: hbye +creation_date: 2017-02-22T12:03:16Z + +[Term] +id: GO:1905960 +name: response to differentiation-inducing factor 2 +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus." [GO_REF:0000071, GOC:rjd, GOC:TermGenie, PMID:19684855, PMID:3355503] +synonym: "response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one" EXACT [] +synonym: "response to DIF-2" RELATED [] +synonym: "response to DIF2" RELATED [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0045472 ! response to ether +is_a: GO:1901654 ! response to ketone +created_by: tb +creation_date: 2017-02-22T18:45:40Z + +[Term] +id: GO:1905961 +name: protein-cysteine S-palmitoyltransferase complex +namespace: cellular_component +def: "A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity." [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:20851885] +comment: An example of this is ERF2 in Saccharomyces cerevisiae (Q06551) in PMID:20851885 (inferred from direct assay) +synonym: "Palmitoyltransferase ERF2-SHR5 complex" NARROW [] +synonym: "Palmitoyltransferase ERF2/SHR5 complex" NARROW [] +is_a: GO:0002178 ! palmitoyltransferase complex +created_by: bhm +creation_date: 2017-02-23T13:33:15Z + +[Term] +id: GO:1905962 +name: glutamatergic neuron differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron." [GO_REF:0000086, GOC:TermGenie, PMID:24030726] +is_a: GO:0030182 ! neuron differentiation +created_by: sl +creation_date: 2017-02-23T17:40:43Z + +[Term] +id: GO:1990000 +name: amyloid fibril formation +namespace: biological_process +def: "The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins." [GOC:cvs, GOC:jj, GOC:ppm, GOC:sj, PMID:21148556, PMID:22817896, PMID:28937655, PMID:29654159] +comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896). +synonym: "amyloid fibril assembly" RELATED [] +synonym: "amyloid structure assembly" RELATED [] +synonym: "amyloid structure formation" RELATED [] +is_a: GO:0019538 ! protein metabolic process +is_a: GO:0097435 ! supramolecular fiber organization +created_by: pr +creation_date: 2012-11-27T16:01:02Z + +[Term] +id: GO:1990001 +name: inhibition of cysteine-type endopeptidase activity involved in apoptotic process +namespace: biological_process +def: "Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process." [GOC:mtg_apoptosis, PMID:11943137] +is_a: GO:0043154 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:0097340 ! inhibition of cysteine-type endopeptidase activity +created_by: pr +creation_date: 2012-12-05T15:42:50Z + +[Term] +id: GO:1990002 +name: methylglyoxal reductase (NADPH-dependent, acetol producing) +namespace: molecular_function +def: "Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+." [EC:1.1.1.-, MetaCyc:RXN0-4281, PMID:16077126, RHEA:27986] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: jl +creation_date: 2012-12-05T15:55:06Z + +[Term] +id: GO:1990003 +name: IDP phosphatase activity +namespace: molecular_function +alt_id: GO:0090450 +def: "Catalysis of the reaction: IDP + H2O = IMP + phosphate." [PMID:20385596, PMID:22849572] +synonym: "IDPase activity" EXACT [] +synonym: "inosine diphosphatase activity" EXACT [] +synonym: "inosine-diphosphatase activity" EXACT [] +xref: EC:3.1.3 +xref: Reactome:R-HSA-2509816 "NUDT16 hydrolyses IDP to IMP" +is_a: GO:0017110 ! nucleoside-diphosphatase activity +is_a: GO:0098519 ! nucleotide phosphatase activity, acting on free nucleotides +created_by: jl +creation_date: 2012-12-05T16:46:52Z + +[Term] +id: GO:1990004 +name: XDP phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: XDP + H2O = XMP + phosphate." [PMID:20385596] +is_a: GO:0098519 ! nucleotide phosphatase activity, acting on free nucleotides +created_by: jl +creation_date: 2012-12-11T14:01:34Z + +[Term] +id: GO:1990005 +name: granular vesicle +namespace: cellular_component +def: "A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells." [NIF_Subcellular:sao478230652] +xref: NIF_Subcellular:sao478230652 +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: pr +creation_date: 2012-12-11T14:51:48Z + +[Term] +id: GO:1990006 +name: amorphous vesicle +namespace: cellular_component +def: "A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway." [NIF_Subcellular:sao1531915298, PMID:11896161] +xref: NIF_Subcellular:sao1531915298 +is_a: GO:0031410 ! cytoplasmic vesicle +created_by: pr +creation_date: 2012-12-11T14:55:36Z + +[Term] +id: GO:1990007 +name: membrane stack +namespace: cellular_component +def: "A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures." [ISBN:9780195065718, NIF_Subcellular:sao2114874506] +xref: NIF_Subcellular:sao2114874506 +is_a: GO:0005783 ! endoplasmic reticulum +created_by: pr +creation_date: 2012-12-11T14:58:16Z + +[Term] +id: GO:1990008 +name: neurosecretory vesicle +namespace: cellular_component +def: "A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus." [ISBN:0195065719, NIF_Subcellular:sao2031592629] +xref: NIF_Subcellular:sao2031592629 +is_a: GO:1990005 ! granular vesicle +created_by: pr +creation_date: 2012-12-12T09:56:14Z + +[Term] +id: GO:1990009 +name: retinal cell apoptotic process +namespace: biological_process +alt_id: GO:0046674 +def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675] +synonym: "induction of retinal programmed cell death" RELATED [] +is_a: GO:0006915 ! apoptotic process +created_by: pr +creation_date: 2012-12-12T10:15:08Z + +[Term] +id: GO:1990010 +name: compound eye retinal cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768] +is_a: GO:1990009 ! retinal cell apoptotic process +created_by: pr +creation_date: 2012-12-12T10:21:07Z + +[Term] +id: GO:1990011 +name: laminated body +namespace: cellular_component +def: "Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus." [ISBN:0195065719, NIF_Subcellular:sao506721981] +synonym: "laminated inclusion body" EXACT [] +xref: NIF_Subcellular:sao506721981 +is_a: GO:0016234 ! inclusion body +created_by: pr +creation_date: 2012-12-12T14:12:21Z + +[Term] +id: GO:1990012 +name: complex laminated body +namespace: cellular_component +def: "A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint." [NIF_Subcellular:nlx_151681] +synonym: "CLB" RELATED [] +xref: NIF_Subcellular:nlx_151681 +is_a: GO:1990011 ! laminated body +created_by: pr +creation_date: 2012-12-12T14:18:15Z + +[Term] +id: GO:1990013 +name: presynaptic grid +namespace: cellular_component +def: "A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane." [ISBN:0716723808, NIF_Subcellular:sao1730664005] +synonym: "pre-synaptic grid" EXACT [] +xref: NIF_Subcellular:sao1730664005 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0048786 ! presynaptic active zone +created_by: pr +creation_date: 2012-12-13T09:00:35Z + +[Term] +id: GO:1990014 +name: orthogonal array +namespace: cellular_component +def: "Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels)." [NIF_Subcellular:sao1747012216, PMID:22718347] +synonym: "OAP" RELATED [] +synonym: "orthogonal array of particles" EXACT [] +synonym: "square array" RELATED [] +xref: NIF_Subcellular:sao1747012216 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005886 ! plasma membrane +created_by: pr +creation_date: 2012-12-13T20:14:15Z + +[Term] +id: GO:1990015 +name: ensheathing process +namespace: cellular_component +def: "A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma." [NIF_Subcellular:sao1376748732] +synonym: "ensheathing process of Schwann cell" NARROW [] +xref: NIF_Subcellular:sao1376748732 +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2012-12-19T09:42:15Z + +[Term] +id: GO:1990016 +name: neck portion of tanycyte +namespace: cellular_component +def: "Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS." [ISBN:0195065719, NIF_Subcellular:sao901230115] +synonym: "neck portion" BROAD [] +xref: NIF_Subcellular:sao901230115 +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2012-12-19T15:17:17Z + +[Term] +id: GO:1990017 +name: somatic portion of tanycyte +namespace: cellular_component +def: "Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS." [ISBN:0195065719, NIF_Subcellular:sao401910342] +synonym: "somatic portion" BROAD [] +xref: NIF_Subcellular:sao401910342 +is_a: GO:0044297 ! cell body +created_by: pr +creation_date: 2012-12-19T15:19:25Z + +[Term] +id: GO:1990018 +name: tail portion of tanycyte +namespace: cellular_component +def: "Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell." [ISBN:0195065719, NIF_Subcellular:sao1749953771] +synonym: "tail portion" BROAD [] +xref: NIF_Subcellular:sao1749953771 +is_a: GO:0110165 ! cellular anatomical entity +created_by: pr +creation_date: 2012-12-19T15:21:20Z + +[Term] +id: GO:1990019 +name: protein storage vacuole organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole." [GOC:tb, PMID:21670741] +is_a: GO:0007033 ! vacuole organization +created_by: tb +creation_date: 2012-12-20T21:00:09Z + +[Term] +id: GO:1990020 +name: recurrent axon collateral +namespace: cellular_component +def: "Axon collateral that ramifies in the area of the soma of the cell of origin." [NIF_Subcellular:sao1642494436] +synonym: "recurrent collateral" BROAD [] +xref: NIF_Subcellular:sao1642494436 +is_a: GO:0044303 ! axon collateral +created_by: pr +creation_date: 2013-01-10T16:04:31Z + +[Term] +id: GO:1990021 +name: Schaffer axon collateral +namespace: cellular_component +def: "Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1." [NIF_Subcellular:nlx_subcell_20090511] +synonym: "Schaffer collateral" BROAD [NIF_Subcellular:sao1950673097] +xref: NIF_Subcellular:nlx_subcell_20090511 +is_a: GO:0044303 ! axon collateral +created_by: pr +creation_date: 2013-01-10T16:06:17Z + +[Term] +id: GO:1990022 +name: obsolete RNA polymerase III complex import into nucleus +namespace: biological_process +def: "OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus." [GOC:mcc, PMID:23267056] +comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. +synonym: "DNA-directed RNA polymerase III complex import into nucleus" EXACT [] +synonym: "DNA-directed RNA polymerase III complex localization to nucleus" EXACT [] +synonym: "RNA polymerase III complex import into nucleus" EXACT [] +synonym: "RNA polymerase III complex localisation to nucleus" EXACT [] +synonym: "RNA polymerase III complex localization to nucleus" RELATED [] +is_obsolete: true +consider: GO:0006606 +created_by: pr +creation_date: 2013-01-15T12:46:26Z + +[Term] +id: GO:1990023 +name: mitotic spindle midzone +namespace: cellular_component +def: "The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner." [GOC:mtg_cell_cycle, GOC:vw] +is_a: GO:0051233 ! spindle midzone +relationship: part_of GO:0072686 ! mitotic spindle +created_by: vw +creation_date: 2013-02-05T15:41:48Z + +[Term] +id: GO:1990024 +name: C bouton +namespace: cellular_component +def: "Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons." [NIF_Subcellular:nlx_subcell_100208] +xref: NIF_Subcellular:nlx_subcell_100208 +is_a: GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2013-02-06T10:27:41Z + +[Term] +id: GO:1990025 +name: F bouton +namespace: cellular_component +def: "Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles." [NIF_Subcellular:nlx_subcell_100206] +xref: NIF_Subcellular:nlx_subcell_100206 +is_a: GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2013-02-06T10:29:42Z + +[Term] +id: GO:1990026 +name: hippocampal mossy fiber expansion +namespace: cellular_component +def: "Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites." [NIF_Subcellular:nlx_subcell_1005002] +synonym: "dentate gyrus granule cell axonal bouton" RELATED [] +synonym: "dentate gyrus mossy fiber expansion" RELATED [] +synonym: "mossy fiber expansion" BROAD [] +xref: NIF_Subcellular:nlx_subcell_1005002 +is_a: GO:0043195 ! terminal bouton +relationship: part_of GO:0097457 ! hippocampal mossy fiber +created_by: pr +creation_date: 2013-02-06T10:31:59Z + +[Term] +id: GO:1990027 +name: S bouton +namespace: cellular_component +def: "Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles." [NIF_Subcellular:nlx_subcell_100207] +xref: NIF_Subcellular:nlx_subcell_100207 +is_a: GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2013-02-06T10:35:12Z + +[Term] +id: GO:1990028 +name: intermediate voltage-gated calcium channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded." [GOC:BHF, GOC:rl, PMID:16382099, Wikipedia:Calcium_channel] +synonym: "R-type calcium channel" RELATED [] +is_a: GO:0005245 ! voltage-gated calcium channel activity +created_by: pr +creation_date: 2013-02-06T20:55:41Z + +[Term] +id: GO:1990029 +name: vasomotion +namespace: biological_process +def: "The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm." [GOC:sl, PMID:14993429, PMID:15678091, PMID:1932763] +is_a: GO:0003013 ! circulatory system process +created_by: tb +creation_date: 2013-02-06T22:30:21Z + +[Term] +id: GO:1990030 +name: pericellular basket +namespace: cellular_component +def: "Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name." [NIF_Subcellular:sao413722576] +synonym: "peri cellular basket" EXACT [] +synonym: "peri-cellular basket" EXACT [] +xref: NIF_Subcellular:sao413722576 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +created_by: pr +creation_date: 2013-02-07T12:53:54Z + +[Term] +id: GO:1990031 +name: pinceau fiber +namespace: cellular_component +def: "Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment." [NIF_Subcellular:sao109906988] +xref: NIF_Subcellular:sao109906988 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0030424 ! axon +created_by: pr +creation_date: 2013-02-07T12:56:50Z + +[Term] +id: GO:1990032 +name: parallel fiber +namespace: cellular_component +def: "A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium." [ISBN:0195159551, NIF_Subcellular:nlx_330] +xref: NIF_Subcellular:nlx_330 +is_a: GO:0030424 ! axon +created_by: pr +creation_date: 2013-02-07T12:58:43Z + +[Term] +id: GO:1990033 +name: dendritic branch point +namespace: cellular_component +def: "The part of a dendritic tree where it branches, giving rise to a dendritic branch." [GOC:aruk, GOC:bc, NIF_Subcellular:sao1348591767] +synonym: "branch point of dendrite" EXACT [] +xref: NIF_Subcellular:sao1348591767 +is_a: GO:0061845 ! neuron projection branch point +relationship: part_of GO:0097447 ! dendritic tree +created_by: pr +creation_date: 2013-02-07T13:01:01Z + +[Term] +id: GO:1990034 +name: calcium ion export across plasma membrane +namespace: biological_process +def: "The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region." [GOC:mah, PMID:2145281] +synonym: "calcium ion efflux from cell" EXACT [GOC:vw, PMID:2145281] +synonym: "calcium ion export from cell" EXACT [] +is_a: GO:0060401 ! cytosolic calcium ion transport +is_a: GO:0070588 ! calcium ion transmembrane transport +is_a: GO:0140115 ! export across plasma membrane +is_a: GO:1901660 ! calcium ion export +created_by: mah +creation_date: 2013-02-07T13:01:29Z + +[Term] +id: GO:1990036 +name: calcium ion import into sarcoplasmic reticulum +namespace: biological_process +def: "The directed movement of calcium ions into a sarcoplasmic reticulum." [GOC:BHF, PMID:17286271] +is_a: GO:0046907 ! intracellular transport +is_a: GO:0070296 ! sarcoplasmic reticulum calcium ion transport +is_a: GO:0070509 ! calcium ion import +relationship: occurs_in GO:0005737 ! cytoplasm +created_by: tb +creation_date: 2013-02-07T23:22:27Z + +[Term] +id: GO:1990037 +name: Lewy body core +namespace: cellular_component +def: "The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments." [NIF_Subcellular:sao6587439252] +xref: NIF_Subcellular:sao6587439252 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097413 ! Lewy body +created_by: pr +creation_date: 2013-02-08T12:56:59Z + +[Term] +id: GO:1990038 +name: Lewy body corona +namespace: cellular_component +def: "The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array." [NIF_Subcellular:sao5764355747] +synonym: "halo" BROAD [] +xref: NIF_Subcellular:sao5764355747 +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0097413 ! Lewy body +created_by: pr +creation_date: 2013-02-08T13:03:27Z + +[Term] +id: GO:1990039 +name: hypolemmal cisterna +namespace: cellular_component +def: "Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer." [ISBN:0195065719, NIF_Subcellular:sao1634374950] +synonym: "hypolemmal cisternae" EXACT [] +xref: NIF_Subcellular:sao1634374950 +is_a: GO:0120082 ! smooth endoplasmic reticulum cisterna +created_by: pr +creation_date: 2013-02-11T15:04:56Z + +[Term] +id: GO:1990040 +name: sub-surface cisterna +namespace: cellular_component +def: "Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane." [ISBN:0195065719, NIF_Subcellular:sao128470897] +synonym: "sub-surface cisternae" EXACT [] +xref: NIF_Subcellular:sao128470897 +is_a: GO:1990039 ! hypolemmal cisterna +created_by: pr +creation_date: 2013-02-11T15:10:47Z + +[Term] +id: GO:1990042 +name: glycerol dehydrogenase [NAD(P)+] activity +namespace: molecular_function +def: "Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced." [PMID:22979944] +synonym: "glycerol dehydrogenase activity, NAD or NADP as acceptor" EXACT [] +is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +created_by: rb +creation_date: 2013-02-14T00:34:45Z + +[Term] +id: GO:1990043 +name: 5' deoxyribonuclease (pyrimidine dimer) activity +namespace: molecular_function +def: "Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate." [EC:3.1.25.-, GOC:al, PMID:9708997] +is_a: GO:0033892 ! deoxyribonuclease (pyrimidine dimer) activity +created_by: pr +creation_date: 2013-02-15T12:16:51Z + +[Term] +id: GO:1990044 +name: protein localization to lipid droplet +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet." [GOC:sart, PMID:22505614] +synonym: "protein localisation to adiposome" EXACT [] +synonym: "protein localisation to lipid body" EXACT [] +synonym: "protein localisation to lipid droplet" EXACT [] +synonym: "protein localisation to lipid particle" EXACT [] +synonym: "protein localization to adiposome" EXACT [] +synonym: "protein localization to lipid body" EXACT [] +synonym: "protein localization to lipid particle" EXACT [] +is_a: GO:0033365 ! protein localization to organelle +created_by: sart +creation_date: 2013-02-15T12:40:57Z + +[Term] +id: GO:1990045 +name: sclerotium development +namespace: biological_process +def: "The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions." [GOC:di, PMID:21148914] +is_a: GO:0048856 ! anatomical structure development +created_by: pr +creation_date: 2013-02-15T15:30:00Z + +[Term] +id: GO:1990046 +name: stress-induced mitochondrial fusion +namespace: biological_process +def: "Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis." [GOC:lb, PMID:19360003] +synonym: "mitochondrial fusion in response to stress" RELATED [] +synonym: "SIMH" NARROW [] +synonym: "stress-induced mitochondrial hyperfusion" NARROW [] +is_a: GO:0008053 ! mitochondrial fusion +is_a: GO:0033554 ! cellular response to stress +created_by: pr +creation_date: 2013-02-15T16:01:55Z + +[Term] +id: GO:1990047 +name: spindle matrix +namespace: cellular_component +def: "A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis." [GOC:ans, PMID:19273613, PMID:22855526] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005856 ! cytoskeleton +created_by: pr +creation_date: 2013-02-18T08:51:47Z + +[Term] +id: GO:1990048 +name: anterograde neuronal dense core vesicle transport +namespace: biological_process +def: "The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse." [GOC:kmv, PMID:23358451] +subset: goslim_synapse +synonym: "anterograde dense core granule trafficking" EXACT [] +synonym: "anterograde dense core granule transport" EXACT [] +is_a: GO:0008089 ! anterograde axonal transport +is_a: GO:0047496 ! vesicle transport along microtubule +is_a: GO:0099519 ! dense core granule cytoskeletal transport + +[Term] +id: GO:1990049 +name: retrograde neuronal dense core vesicle transport +namespace: biological_process +def: "The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body." [GOC:kmv, PMID:23358451, PMID:24762653] +subset: goslim_synapse +synonym: "retrograde dense core granule trafficking" EXACT [] +synonym: "retrograde dense core granule transport" EXACT [] +is_a: GO:0008090 ! retrograde axonal transport +is_a: GO:0047496 ! vesicle transport along microtubule +is_a: GO:0099519 ! dense core granule cytoskeletal transport +created_by: pr +creation_date: 2013-02-19T13:31:44Z + +[Term] +id: GO:1990050 +name: phosphatidic acid transfer activity +namespace: molecular_function +def: "Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3." [PMID:23042293] +synonym: "intermembrane PA transfer activity" EXACT [] +synonym: "intermembrane phosphatidic acid transfer activity" NARROW [] +synonym: "phosphatidic acid carrier activity" EXACT [] +synonym: "phosphatidic acid transporter activity" BROAD [] +is_a: GO:0120014 ! phospholipid transfer activity +created_by: rb +creation_date: 2013-02-21T00:45:28Z + +[Term] +id: GO:1990051 +name: activation of protein kinase C activity +namespace: biological_process +def: "Any process that initiates the activity of the inactive enzyme protein kinase C." [PMID:3156004] +synonym: "PKC activation" EXACT [] +synonym: "protein kinase C activation" EXACT [] +is_a: GO:0032147 ! activation of protein kinase activity +created_by: sl +creation_date: 2013-02-21T19:57:54Z + +[Term] +id: GO:1990052 +name: ER to chloroplast lipid transport +namespace: biological_process +def: "The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast." [PMID:18689504] +synonym: "endoplasmic reticulum to chloroplast lipid transport" EXACT [] +synonym: "ER to chloroplast lipid trafficking" EXACT [] +is_a: GO:0032365 ! intracellular lipid transport +is_a: GO:1901965 ! endoplasmic reticulum to chloroplast transport +created_by: tb +creation_date: 2013-02-22T00:05:23Z + +[Term] +id: GO:1990053 +name: DNA-5-methylcytosine glycosylase activity +namespace: molecular_function +def: "Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site." [PMID:23316050] +is_a: GO:0003905 ! alkylbase DNA N-glycosylase activity +created_by: tb +creation_date: 2013-02-22T01:09:06Z + +[Term] +id: GO:1990054 +name: response to temozolomide +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus." [GOC:hp] +comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC. +subset: gocheck_do_not_manually_annotate +is_a: GO:0010243 ! response to organonitrogen compound +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:0097327 ! response to antineoplastic agent +is_a: GO:1901700 ! response to oxygen-containing compound +created_by: pr +creation_date: 2013-02-22T10:09:44Z + +[Term] +id: GO:1990055 +name: phenylacetaldehyde synthase activity +namespace: molecular_function +def: "Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2." [MetaCyc:RXN-8990, PMID:16766535, PMID:23204519] +synonym: "aromatic aldehyde synthase" BROAD [] +xref: EC:4.1.1.109 +is_a: GO:0016831 ! carboxy-lyase activity +created_by: tb +creation_date: 2013-02-25T20:22:35Z + +[Term] +id: GO:1990056 +name: obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process +namespace: molecular_function +def: "OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process." [PMID:21098119, PMID:21993622, PMID:23264631] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process" EXACT [] +is_obsolete: true +created_by: rb +creation_date: 2013-02-26T21:28:08Z + +[Term] +id: GO:1990057 +name: obsolete cell cycle arrest in response to DNA damage stimulus +namespace: biological_process +def: "OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism." [GOC:rph, PMID:10630641] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "cell cycle arrest in response to DNA damage stimulus" EXACT [] +is_obsolete: true +created_by: rph +creation_date: 2013-03-06T13:48:44Z + +[Term] +id: GO:1990058 +name: fruit replum development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum." [PMID:23133401, PO:0025267] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0010154 ! fruit development +created_by: dhl +creation_date: 2013-03-12T21:15:15Z + +[Term] +id: GO:1990059 +name: fruit valve development +namespace: biological_process +def: "The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces." [PMID:23133401, PO:0000033] +is_a: GO:0003006 ! developmental process involved in reproduction +is_a: GO:0009791 ! post-embryonic development +is_a: GO:0048856 ! anatomical structure development +relationship: part_of GO:0010154 ! fruit development +created_by: dhl +creation_date: 2013-03-12T21:21:15Z + +[Term] +id: GO:1990060 +name: maltose transport complex +namespace: cellular_component +def: "Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK." [PMID:18033289] +synonym: "maltose ABC transporter complex" EXACT [] +synonym: "maltose ATP-binding cassette transporter complex" EXACT [] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: jl +creation_date: 2013-03-13T13:52:48Z + +[Term] +id: GO:1990061 +name: bacterial degradosome +namespace: cellular_component +def: "The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase." [GOC:bhm, PMID:21805185] +is_a: GO:0000177 ! cytoplasmic exosome (RNase complex) +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-03-20T13:51:49Z + +[Term] +id: GO:1990062 +name: RPAP3/R2TP/prefoldin-like complex +namespace: cellular_component +def: "A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity." [GOC:pr, PMID:20453924, PMID:21925213, PMID:22418846] +synonym: "R2TP/prefoldin-like complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2013-03-20T15:31:12Z + +[Term] +id: GO:1990063 +name: Bam protein complex +namespace: cellular_component +def: "Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex." [GOC:bhm, PMID:20378773] +synonym: "OMP complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0031246 ! intrinsic component of periplasmic side of cell outer membrane +created_by: bhm +creation_date: 2013-03-20T15:42:57Z + +[Term] +id: GO:1990064 +name: ground tissue pattern formation +namespace: biological_process +def: "The regionalization process that gives rise to the patterning of the ground tissue." [PMID:23444357] +synonym: "ground tissue patterning" EXACT [] +is_a: GO:0003002 ! regionalization +created_by: tb +creation_date: 2013-03-21T23:24:44Z + +[Term] +id: GO:1990065 +name: Dxr protein complex +namespace: cellular_component +def: "A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)." [GOC:bhm, PMID:15339150] +synonym: "1-deoxy-D-xylulose 5-phosphate reductoisomerase complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2013-03-27T16:58:54Z + +[Term] +id: GO:1990066 +name: energy quenching +namespace: biological_process +def: "The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence." [PMID:10938857] +is_a: GO:0009416 ! response to light stimulus +created_by: tb +creation_date: 2013-03-27T21:02:00Z + +[Term] +id: GO:1990067 +name: intrachromosomal DNA recombination +namespace: biological_process +def: "The process of DNA recombination occurring within a single chromosome." [PMID:7748165] +synonym: "intrastrand DNA recombination" EXACT [] +is_a: GO:0006310 ! DNA recombination +created_by: tb +creation_date: 2013-03-27T21:11:35Z + +[Term] +id: GO:1990068 +name: seed dehydration +namespace: biological_process +def: "The seed development process whose outcome is the drying of a maturing seed." [PMID:20138563] +is_a: GO:0048609 ! multicellular organismal reproductive process +relationship: part_of GO:0010431 ! seed maturation +created_by: tb +creation_date: 2013-03-27T21:16:03Z + +[Term] +id: GO:1990069 +name: stomatal opening +namespace: biological_process +def: "The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange." [PMID:21749899] +is_a: GO:0010118 ! stomatal movement +created_by: tb +creation_date: 2013-03-27T21:18:48Z + +[Term] +id: GO:1990070 +name: TRAPPI protein complex +namespace: cellular_component +def: "A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast." [GOC:bhm, PMID:20375281, PMID:22669257] +synonym: "TRAPP core complex" EXACT [] +is_a: GO:0030008 ! TRAPP complex +relationship: part_of GO:0005793 ! endoplasmic reticulum-Golgi intermediate compartment +created_by: bhm +creation_date: 2013-03-28T14:04:40Z + +[Term] +id: GO:1990071 +name: TRAPPII protein complex +namespace: cellular_component +def: "A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself." [GOC:bhm, PMID:20375281, PMID:22669257] +is_a: GO:0030008 ! TRAPP complex +relationship: part_of GO:0005768 ! endosome +relationship: part_of GO:0005794 ! Golgi apparatus +created_by: bhm +creation_date: 2013-03-28T14:24:08Z + +[Term] +id: GO:1990072 +name: TRAPPIII protein complex +namespace: cellular_component +def: "A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins." [GOC:bhm, PMID:20375281, PMID:22669257] +is_a: GO:0030008 ! TRAPP complex +relationship: part_of GO:0005794 ! Golgi apparatus +created_by: bhm +creation_date: 2013-03-28T14:28:59Z + +[Term] +id: GO:1990073 +name: perforation plate +namespace: cellular_component +def: "A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations)." [GOC:PO_curators, ISBN:0471245194] +comment: Part of a vessel member (PO:0002003). May be simple, with one perforation, or multiperforate, with more than one perforation. Perforation plates are usually on the end walls of a cell, but may also be on the side walls. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005618 ! cell wall +created_by: tb +creation_date: 2013-03-29T00:53:28Z + +[Term] +id: GO:1990074 +name: polyuridylation-dependent mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA." [GOC:vw, PMID:23503588] +is_a: GO:0006402 ! mRNA catabolic process +is_a: GO:0043632 ! modification-dependent macromolecule catabolic process +created_by: tb +creation_date: 2013-04-16T22:51:46Z + +[Term] +id: GO:1990075 +name: periciliary membrane compartment +namespace: cellular_component +def: "A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis." [GOC:cilia, GOC:dr, GOC:krc, PMID:22342749] +synonym: "PCMC" EXACT [] +is_a: GO:0098590 ! plasma membrane region +created_by: pr +creation_date: 2013-04-24T10:14:50Z + +[Term] +id: GO:1990076 +name: cell wall polysaccharide catabolic process involved in abscission +namespace: biological_process +def: "Any cell wall polysaccharide catabolic process that is involved in abscission." [GOC:TermGenie, PMID:23479623] +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +intersection_of: GO:0044347 ! cell wall polysaccharide catabolic process +intersection_of: part_of GO:0009838 ! abscission +relationship: part_of GO:0009838 ! abscission +created_by: dhl +creation_date: 2013-04-25T16:29:43Z + +[Term] +id: GO:1990077 +name: primosome complex +namespace: cellular_component +def: "Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart." [GOC:bhm, GOC:mah, PMID:21856207] +synonym: "primosome" EXACT [] +is_a: GO:0032993 ! protein-DNA complex +relationship: part_of GO:0030894 ! replisome +created_by: bhm +creation_date: 2013-04-26T11:55:28Z + +[Term] +id: GO:1990078 +name: replication inhibiting complex +namespace: cellular_component +def: "A protein complex that inhibits multiple events of replication initiation during one replication cycle." [GOC:bhm, PMID:21708944] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030894 ! replisome +created_by: bhm +creation_date: 2013-04-26T13:07:03Z + +[Term] +id: GO:1990079 +name: cartilage homeostasis +namespace: biological_process +alt_id: GO:1902094 +alt_id: GO:1902095 +alt_id: GO:1902096 +def: "A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function." [GOC:hjd, PMID:21652695] +synonym: "negative regulation of cartilage homeostasis" RELATED [] +synonym: "positive regulation of cartilage homeostasis" RELATED [] +synonym: "regulation of cartilage homeostasis" RELATED [] +is_a: GO:0001894 ! tissue homeostasis +created_by: hjd +creation_date: 2013-04-29T20:10:15Z + +[Term] +id: GO:1990080 +name: 2-phenylethylamine receptor activity +namespace: molecular_function +def: "Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity." [PMID:16878137] +synonym: "beta-phenylethylamine receptor activity" EXACT [] +is_a: GO:0008227 ! G protein-coupled amine receptor activity +created_by: sp +creation_date: 2013-04-30T10:53:19Z + +[Term] +id: GO:1990081 +name: trimethylamine receptor activity +namespace: molecular_function +def: "Combining with the biogenic amine trimethylamine to initiate a change in cell activity." [PMID:16878137] +is_a: GO:0001594 ! trace-amine receptor activity +created_by: sp +creation_date: 2013-04-30T10:57:07Z + +[Term] +id: GO:1990082 +name: DnaA-L2 complex +namespace: cellular_component +def: "A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2." [GOC:bhm, PMID:21288885] +is_a: GO:1990078 ! replication inhibiting complex +created_by: bhm +creation_date: 2013-04-30T11:46:41Z + +[Term] +id: GO:1990083 +name: DnaA-Hda complex +namespace: cellular_component +def: "A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda." [GOC:bhm, PMID:21708944] +is_a: GO:1990078 ! replication inhibiting complex +created_by: bhm +creation_date: 2013-04-30T11:49:04Z + +[Term] +id: GO:1990084 +name: DnaA-Dps complex +namespace: cellular_component +def: "A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps." [GOC:bhm, PMID:18284581] +is_a: GO:1990078 ! replication inhibiting complex +created_by: bhm +creation_date: 2013-04-30T11:50:17Z + +[Term] +id: GO:1990085 +name: Hda-beta clamp complex +namespace: cellular_component +def: "A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda." [GOC:bhm, PMID:15150238] +synonym: "Hda-DnaN complex" EXACT [] +synonym: "Hda-dpo3b complex" EXACT [] +is_a: GO:1990078 ! replication inhibiting complex +created_by: bhm +creation_date: 2013-04-30T11:53:18Z + +[Term] +id: GO:1990086 +name: lens fiber cell apoptotic process +namespace: biological_process +def: "Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [CL:0011004, GOC:hjd, PMID:11095619] +is_a: GO:1904019 ! epithelial cell apoptotic process +created_by: hjd +creation_date: 2013-05-01T19:09:28Z + +[Term] +id: GO:1990088 +name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]." [GOC:hjd, PMID:10077852] +xref: EC:2.1.1.246 +is_a: GO:0008168 ! methyltransferase activity +created_by: hjd +creation_date: 2013-05-06T15:07:20Z + +[Term] +id: GO:1990089 +name: response to nerve growth factor +namespace: biological_process +def: "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus." [PMID:22399805] +synonym: "response to nerve growth factor stimulus" EXACT [GOC:dos] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: sl +creation_date: 2013-05-06T17:08:47Z + +[Term] +id: GO:1990090 +name: cellular response to nerve growth factor stimulus +namespace: biological_process +def: "A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus." [PMID:22399805, Wikipedia:Nerve_growth_factor] +synonym: "cellular response to NGF" EXACT [GOC:bf, Wikipedia:Nerve_growth_factor] +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:1990089 ! response to nerve growth factor +created_by: sl +creation_date: 2013-05-06T17:13:36Z + +[Term] +id: GO:1990091 +name: sodium-dependent self proteolysis +namespace: biological_process +def: "The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds." [PMID:20460380] +is_a: GO:0097264 ! self proteolysis +created_by: sl +creation_date: 2013-05-06T17:30:23Z + +[Term] +id: GO:1990092 +name: calcium-dependent self proteolysis +namespace: biological_process +def: "The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds." [PMID:20460380] +is_a: GO:0097264 ! self proteolysis +created_by: sl +creation_date: 2013-05-06T17:33:34Z + +[Term] +id: GO:1990093 +name: obsolete negative regulation of N-methyl-D-aspartate receptor clustering +namespace: biological_process +def: "OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane." [PMID:18442977] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "negative regulation of N-methyl-D-aspartate receptor clustering" EXACT [] +synonym: "negative regulation of NMDA receptor clustering" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2013-05-06T17:39:44Z + +[Term] +id: GO:1990094 +name: obsolete positive regulation of N-methyl-D-aspartate receptor clustering +namespace: biological_process +def: "OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane." [PMID:18442977] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "positive regulation of N-methyl-D-aspartate receptor clustering" EXACT [] +synonym: "positive regulation of NMDA receptor clustering" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2013-05-06T17:44:00Z + +[Term] +id: GO:1990095 +name: positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:kmv, PMID:16166371] +is_a: GO:0036091 ! positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress +relationship: part_of GO:0034614 ! cellular response to reactive oxygen species +created_by: pr +creation_date: 2013-05-07T12:10:32Z + +[Term] +id: GO:1990096 +name: positive regulation of transcription from RNA polymerase II promoter in response to superoxide +namespace: biological_process +def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:kmv, PMID:12869585, PMID:16166371] +is_a: GO:1990095 ! positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species +relationship: part_of GO:0071451 ! cellular response to superoxide +created_by: pr +creation_date: 2013-05-07T12:25:34Z + +[Term] +id: GO:1990097 +name: SeqA-DNA complex +namespace: cellular_component +def: "A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle." [GOC:bhm, PMID:12379844, PMID:15933720, PMID:23149570] +synonym: "SeqA-dsDNA complex" NARROW [] +synonym: "SeqA-hemimethylated DNA complex" NARROW [] +synonym: "SeqA-hemimethylation dsDNA complex" NARROW [] +is_a: GO:0032993 ! protein-DNA complex +created_by: bhm +creation_date: 2013-05-13T11:18:11Z + +[Term] +id: GO:1990098 +name: core primosome complex +namespace: cellular_component +def: "A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication." [GOC:bhm, PMID:21856207] +comment: The core primosome refers to a helicase-primase complex, and should not be confused with the more general GO term 'primosome complex ; GO:1990077'. +synonym: "core primosome" EXACT [GOC:bhm] +is_a: GO:1990077 ! primosome complex +created_by: bhm +creation_date: 2013-05-14T10:30:02Z + +[Term] +id: GO:1990099 +name: pre-primosome complex +namespace: cellular_component +def: "Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component." [GOC:bhm, PMID:18179598, PMID:20129058, PMID:8663105] +synonym: "pre-priming complex" EXACT [GOC:bhm] +synonym: "pre-primosome" EXACT [GOC:bhm, PMID:11994158] +synonym: "pre-replication complex" RELATED [GOC:bhm] +synonym: "preprimosome" EXACT [GOC:bhm, PMID:2824502] +synonym: "preprimosome complex" EXACT [GOC:bhm] +synonym: "prereplication complex" EXACT [GOC:bhm] +is_a: GO:1990077 ! primosome complex +created_by: bhm +creation_date: 2013-05-14T10:53:42Z + +[Term] +id: GO:1990100 +name: DnaB-DnaC complex +namespace: cellular_component +def: "A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC)." [GOC:bhm, PMID:20129058] +comment: DnaB and DnaC may be present in different ratios in different forms of the DnaB-DnaC complex, including a DnaB6-DnaC3 complex active at the oriC, and a DnaB6-DnaC6 complex. +synonym: "DnaB6-DnaC3 complex" NARROW [PMID:20129058] +synonym: "DnaB6-DnaC6 complex" NARROW [PMID:20129058] +synonym: "helicase-loading complex" BROAD [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990161 ! DnaB helicase complex +relationship: part_of GO:1990077 ! primosome complex +created_by: bhm +creation_date: 2013-05-14T12:02:22Z + +[Term] +id: GO:1990101 +name: DnaA-oriC complex +namespace: cellular_component +def: "A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle." [GOC:bhm, PMID:19833870] +synonym: "DnaA-DNA complex" BROAD [GOC:bhm] +is_a: GO:1990077 ! primosome complex +created_by: bhm +creation_date: 2013-05-14T12:07:04Z + +[Term] +id: GO:1990102 +name: DnaA-DiaA complex +namespace: cellular_component +def: "A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA." [GOC:bhm, PMID:15326179, PMID:17699754] +synonym: "DnaA-DiaA-DNA complex" EXACT [GOC:bhm] +is_a: GO:1990077 ! primosome complex +relationship: has_part GO:1990101 ! DnaA-oriC complex +relationship: has_part GO:1990125 ! DiaA complex +created_by: bhm +creation_date: 2013-05-14T12:33:59Z + +[Term] +id: GO:1990103 +name: DnaA-HU complex +namespace: cellular_component +def: "A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC." [GOC:bhm, PMID:18179598] +synonym: "DnaA-HU-DNA complex" EXACT [GOC:bhm] +is_a: GO:1990077 ! primosome complex +created_by: bhm +creation_date: 2013-05-14T12:36:39Z + +[Term] +id: GO:1990104 +name: DNA bending complex +namespace: cellular_component +def: "A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction." [GOC:bhm, PMID:17097674] +synonym: "histone-like DNA binding complex" NARROW [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2013-05-20T09:29:06Z + +[Term] +id: GO:1990105 +name: obsolete regulation of voltage-gated potassium channel activity +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity." [PMID:19219384] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of voltage-gated potassium channel activity" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2013-05-21T15:12:06Z + +[Term] +id: GO:1990107 +name: thiazole synthase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O." [EC:2.8.1.10, GOC:cjk, PMID:22031445, RHEA:26297] +comment: H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis. +synonym: "1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity" EXACT [] +is_a: GO:0016783 ! sulfurtransferase activity +relationship: part_of GO:0009228 ! thiamine biosynthetic process +created_by: pr +creation_date: 2013-05-28T12:36:04Z + +[Term] +id: GO:1990108 +name: protein linear deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein." [PMID:23708998] +is_a: GO:0016579 ! protein deubiquitination +created_by: sp +creation_date: 2013-05-29T05:58:49Z + +[Term] +id: GO:1990109 +name: rejection of pollen from other species +namespace: biological_process +def: "The process involved in the rejection of pollen of one species by cells in the stigma of another species." [PMID:21205670] +synonym: "unilateral interspecific incompatibility" EXACT [] +is_a: GO:0022414 ! reproductive process +is_a: GO:0044419 ! interspecies interaction between organisms +relationship: part_of GO:0009875 ! pollen-pistil interaction +created_by: tb +creation_date: 2013-05-29T21:12:09Z + +[Term] +id: GO:1990110 +name: callus formation +namespace: biological_process +def: "The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate." [ISBN:0070187517] +is_a: GO:0032501 ! multicellular organismal process +relationship: part_of GO:0042060 ! wound healing +created_by: tb +creation_date: 2013-05-29T22:02:52Z + +[Term] +id: GO:1990111 +name: spermatoproteasome complex +namespace: cellular_component +def: "A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity." [GOC:sp, PMID:23706739] +is_a: GO:0000502 ! proteasome complex +created_by: sp +creation_date: 2013-05-31T11:56:52Z + +[Term] +id: GO:1990112 +name: RQC complex +namespace: cellular_component +def: "A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins." [GOC:rb, PMID:23178123, PMID:23232563] +synonym: "ribosome quality control complex" EXACT [PMID:23178123, PMID:23232563] +synonym: "ribosome-bound quality control complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2013-05-31T21:42:43Z + +[Term] +id: GO:1990113 +name: RNA polymerase I assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex." [GOC:rb, PMID:23459708] +synonym: "DNA-directed RNA polymerase I complex assembly" EXACT [] +synonym: "RNA Polymerase I complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: rb +creation_date: 2013-05-31T21:44:41Z + +[Term] +id: GO:1990114 +name: RNA polymerase II core complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex." [GOC:rb, PMID:23459708] +synonym: "DNA-directed RNA polymerase II, core complex assembly" EXACT [] +synonym: "RNA Polymerase II assembly" BROAD [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: rb +creation_date: 2013-05-31T21:46:42Z + +[Term] +id: GO:1990115 +name: RNA polymerase III assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex." [GOC:rb, PMID:23459708] +synonym: "DNA-directed RNA polymerase III complex assembly" EXACT [] +synonym: "RNA Polymerase III complex assembly" EXACT [] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: rb +creation_date: 2013-05-31T21:49:19Z + +[Term] +id: GO:1990116 +name: ribosome-associated ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein." [GOC:dgf, PMID:23358411] +synonym: "RAD" BROAD [] +synonym: "ribosome-associated degradation" BROAD [] +synonym: "ribosome-associated ubiquitin-dependent protein breakdown" EXACT [] +synonym: "ribosome-associated ubiquitin-dependent protein catabolism" EXACT [] +synonym: "ribosome-associated ubiquitin-dependent protein degradation" EXACT [] +is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process +created_by: pr +creation_date: 2013-06-05T11:46:01Z + +[Term] +id: GO:1990117 +name: B cell receptor apoptotic signaling pathway +namespace: biological_process +def: "An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, PMID:15214043] +synonym: "B cell receptor extrinsic apoptotic signaling pathway" EXACT [] +synonym: "extrinsic apoptotic signaling pathway via B cell antigen receptor" RELATED [] +synonym: "extrinsic apoptotic signaling pathway via BCR" RELATED [] +is_a: GO:0050853 ! B cell receptor signaling pathway +is_a: GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: part_of GO:0001783 ! B cell apoptotic process +created_by: pr +creation_date: 2013-06-06T15:15:17Z + +[Term] +id: GO:1990119 +name: ATP-dependent RNA helicase inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of ATP-dependent RNA helicase." [GOC:rb, PMID:23721653] +is_a: GO:0042030 ! ATPase inhibitor activity +relationship: negatively_regulates GO:0003724 ! RNA helicase activity +created_by: rb +creation_date: 2013-06-11T21:14:38Z + +[Term] +id: GO:1990120 +name: messenger ribonucleoprotein complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex." [GOC:rb, PMID:23721653] +synonym: "messenger ribonucleoprotein assembly" RELATED [] +synonym: "mRNA-protein complex assembly" EXACT [GOC:bf] +synonym: "mRNP assembly" EXACT [GOC:rb] +synonym: "mRNP complex assembly" EXACT [GOC:bf] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +created_by: rb +creation_date: 2013-06-11T21:18:20Z + +[Term] +id: GO:1990121 +name: H-NS complex +namespace: cellular_component +def: "A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA." [GOC:bhm, PMID:12592399] +synonym: "DNA-binding protein H-NS complex" EXACT [] +synonym: "histone-like protein H-NS complex" EXACT [] +is_a: GO:1990104 ! DNA bending complex +relationship: part_of GO:0005829 ! cytosol +relationship: part_of GO:0043590 ! bacterial nucleoid +created_by: bhm +creation_date: 2013-06-12T10:08:31Z + +[Term] +id: GO:1990124 +name: messenger ribonucleoprotein complex +namespace: cellular_component +def: "A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules." [GOC:bf, PMID:15574591, PMID:21915786] +synonym: "messenger ribonucleoprotein particle" RELATED [PMID:21915786] +synonym: "mRNA-protein complex" EXACT [PMID:21915786] +synonym: "mRNP" EXACT [PMID:21915786] +synonym: "mRNP complex" EXACT [PMID:15574591, PMID:21915786] +is_a: GO:1990904 ! ribonucleoprotein complex +created_by: bf +creation_date: 2013-06-13T09:20:52Z + +[Term] +id: GO:1990125 +name: DiaA complex +namespace: cellular_component +def: "A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation." [GOC:bhm, PMID:17699754] +synonym: "DiaA homotetramer" EXACT [GOC:bf, PMID:17699754] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2013-06-13T14:03:54Z + +[Term] +id: GO:1990126 +name: retrograde transport, endosome to plasma membrane +namespace: biological_process +def: "The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins." [PMID:23563491] +is_a: GO:0016197 ! endosomal transport +is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane +created_by: sp +creation_date: 2013-06-18T10:52:50Z + +[Term] +id: GO:1990127 +name: intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered." [GOC:krc, GOC:mtg_apoptosis, PMID:16571598] +is_a: GO:0008627 ! intrinsic apoptotic signaling pathway in response to osmotic stress +is_a: GO:0072332 ! intrinsic apoptotic signaling pathway by p53 class mediator +created_by: pr +creation_date: 2013-06-19T13:55:06Z + +[Term] +id: GO:1990128 +name: obsolete pre-primosome complex involved in replication initiation +namespace: cellular_component +def: "OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication." [GOC:bhm, PMID:21856207] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "pre-primosome complex involved in replication initiation" EXACT [] +is_obsolete: true +created_by: bhm +creation_date: 2013-06-24T10:29:39Z + +[Term] +id: GO:1990129 +name: obsolete pre-primosome complex involved in replication restart +namespace: cellular_component +def: "OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired." [GOC:bhm, PMID:17139333] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "pre-primosome complex involved in replication restart" EXACT [] +is_obsolete: true +created_by: bhm +creation_date: 2013-06-24T10:36:30Z + +[Term] +id: GO:1990130 +name: GATOR1 complex +namespace: cellular_component +def: "A protein complex involved in regulation of non-nitrogen-starvation (NNS) autophagic process. In S. cerevisiae this complex contains Iml1p, Npr2p and Npr3p proteins. In humans the GATOR1 complex consists of DEPDC5, Nprl2, Nprl3." [GOC:rb, PMID:21900499, PMID:23723238, PMID:23974112, PMID:28199306] +synonym: "IML1 complex" EXACT [] +synonym: "SEACIT complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0035859 ! Seh1-associated complex +created_by: rb +creation_date: 2013-06-25T17:34:40Z + +[Term] +id: GO:1990131 +name: Gtr1-Gtr2 GTPase complex +namespace: cellular_component +def: "A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins." [GOC:rb, PMID:10388807, PMID:16143306] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2013-06-25T20:39:16Z + +[Term] +id: GO:1990132 +name: obsolete release of misfolded protein from chaperone +namespace: biological_process +def: "OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery." [GOC:rb, PMID:23530227] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "release of misfolded protein from chaperone" EXACT [] +is_obsolete: true +created_by: rb +creation_date: 2013-06-25T21:56:37Z + +[Term] +id: GO:1990133 +name: molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex +namespace: cellular_component +def: "A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved." [GOC:bhm, pmid:11713534, pmid:16669776] +is_a: GO:1902503 ! adenylyltransferase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-06-26T10:54:21Z + +[Term] +id: GO:1990134 +name: epithelial cell apoptotic process involved in palatal shelf morphogenesis +namespace: biological_process +def: "An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf." [GOC:dph, GOC:mtg_apoptosis, PMID:16607638] +is_a: GO:0060561 ! apoptotic process involved in morphogenesis +is_a: GO:1904019 ! epithelial cell apoptotic process +relationship: part_of GO:0062009 ! secondary palate development +created_by: dph +creation_date: 2013-06-26T11:56:00Z + +[Term] +id: GO:1990135 +name: flavonoid sulfotransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative." [PMID:23611783] +is_a: GO:0008146 ! sulfotransferase activity +created_by: tb +creation_date: 2013-06-28T22:07:27Z + +[Term] +id: GO:1990136 +name: linoleate 9S-lipoxygenase activity +namespace: molecular_function +def: "Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate." [EC:1.13.11.58, GOC:rph, RHEA:30291] +synonym: "9-lipoxygenase activity" RELATED [] +synonym: "9S-lipoxygenase activity" RELATED [] +synonym: "linoleate 9-lipoxygenase activity" RELATED [] +synonym: "linoleate:oxygen 9S-oxidoreductase activity" EXACT [] +is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +created_by: pr +creation_date: 2013-07-03T12:20:57Z + +[Term] +id: GO:1990137 +name: plant seed peroxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH." [PMID:19467604] +synonym: "peroxygenase activity" RELATED [PMID:19467604] +xref: EC:1.11.2.3 +xref: MetaCyc:RXN-11819 +is_a: GO:0016684 ! oxidoreductase activity, acting on peroxide as acceptor +created_by: tb +creation_date: 2013-07-03T12:49:20Z + +[Term] +id: GO:1990138 +name: neuron projection extension +namespace: biological_process +def: "Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:BHF, GOC:rl, PMID:22790009] +synonym: "neurite extension" NARROW [] +synonym: "neuron process extension" EXACT [] +synonym: "neuron protrusion extension" EXACT [] +synonym: "neuronal cell projection extension" EXACT [] +is_a: GO:0048588 ! developmental cell growth +is_a: GO:0060560 ! developmental growth involved in morphogenesis +relationship: part_of GO:0048812 ! neuron projection morphogenesis +created_by: pr +creation_date: 2013-07-08T08:40:45Z + +[Term] +id: GO:1990139 +name: protein localization to nuclear periphery +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within the nuclear periphery." [GOC:mah, PMID:23703609] +is_a: GO:0034504 ! protein localization to nucleus +created_by: mah +creation_date: 2013-07-09T13:35:49Z + +[Term] +id: GO:1990140 +name: MPT synthase complex +namespace: cellular_component +def: "A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved." [GOC:bhm, PMID:11135669, PMID:16669776, Reactome:R-HSA-947581] +synonym: "molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex" RELATED [] +is_a: GO:1990228 ! sulfurtransferase complex +created_by: pr +creation_date: 2013-07-11T08:32:29Z + +[Term] +id: GO:1990142 +name: envenomation resulting in hemolysis in other organism +namespace: biological_process +def: "A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism." [PMID:21590705] +is_a: GO:0044649 ! envenomation resulting in cytolysis in other organism +created_by: sp +creation_date: 2013-07-18T10:46:03Z + +[Term] +id: GO:1990143 +name: CoA-synthesizing protein complex +namespace: cellular_component +def: "A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway." [GOC:rb, PMID:23789928] +synonym: "CoA-SPC" EXACT [] +synonym: "coenzyme A-synthesizing protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2013-07-18T22:30:20Z + +[Term] +id: GO:1990144 +name: intrinsic apoptotic signaling pathway in response to hypoxia +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, PMID:20436456] +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway +relationship: part_of GO:0071456 ! cellular response to hypoxia +created_by: pr +creation_date: 2013-07-23T10:18:10Z + +[Term] +id: GO:1990145 +name: maintenance of translational fidelity +namespace: biological_process +def: "Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template." [GOC:hjd, ISBN:9781936113460, PMID:21841312] +is_a: GO:0009059 ! macromolecule biosynthetic process +relationship: part_of GO:0006412 ! translation +created_by: hjd +creation_date: 2013-07-24T19:30:09Z + +[Term] +id: GO:1990146 +name: protein localization to rhabdomere +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location within a rhabdomere." [GOC:sart, PMID:8335687] +is_a: GO:0034613 ! cellular protein localization +created_by: sart +creation_date: 2013-07-25T11:24:49Z + +[Term] +id: GO:1990147 +name: talin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types." [GOC:hjd, PMID:23372168] +is_a: GO:0008092 ! cytoskeletal protein binding +created_by: hjd +creation_date: 2013-07-25T19:49:53Z + +[Term] +id: GO:1990148 +name: glutamate dehydrogenase complex +namespace: cellular_component +def: "A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies." [GOC:bhm, PMID:22393408, PMID:23412807] +synonym: "dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex" RELATED [] +synonym: "glutamate dehydrogenase (NADP+) complex" RELATED [] +synonym: "glutamic acid dehydrogenase complex" RELATED [] +synonym: "glutamic dehydrogenase complex" RELATED [] +synonym: "L-glutamate dehydrogenase complex" RELATED [] +synonym: "L-glutamate:NADP+ oxidoreductase (deaminating) complex" RELATED [] +synonym: "L-glutamic acid dehydrogenase complex" RELATED [] +synonym: "NAD(P)-glutamate dehydrogenase complex" RELATED [] +synonym: "NAD(P)H-dependent glutamate dehydrogenase complex" RELATED [] +is_a: GO:1990204 ! oxidoreductase complex +created_by: pr +creation_date: 2013-07-26T10:14:15Z + +[Term] +id: GO:1990149 +name: obsolete COPI vesicle coating +namespace: biological_process +def: "OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat." [GOC:rb, PMID:11970962] +comment: This term was obsoleted at the TermGenie Gatekeeper stage because COPI vesicles are formed on Golgi membranes, and the existing term 'COPI coating of Golgi vesicle ; GO:0048205' describes this process. +synonym: "COPI vesicle coating" EXACT [] +is_obsolete: true +created_by: rb +creation_date: 2013-07-29T22:09:37Z + +[Term] +id: GO:1990150 +name: VEGF-A complex +namespace: cellular_component +def: "A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase." [GOC:bf, GOC:bhm, PMID:12207021, PMID:19658168] +synonym: "vascular endothelial growth factor A complex" EXACT [GOC:bhm] +is_a: GO:0036454 ! growth factor complex +created_by: bhm +creation_date: 2013-07-30T13:24:41Z + +[Term] +id: GO:1990151 +name: protein localization to cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, a location at the cell tip." [PMID:22768263] +synonym: "protein localisation to cell tip" EXACT [GOC:mah] +is_a: GO:0034613 ! cellular protein localization +created_by: mah +creation_date: 2013-07-31T14:56:40Z + +[Term] +id: GO:1990153 +name: maintenance of protein localization to heterochromatin +namespace: biological_process +def: "A process in which a protein is maintained in a location in telomeric heterochromatin." [PMID:21300781] +synonym: "maintenance of protein localisation to heterochromatin" EXACT [GOC:mah] +synonym: "maintenance of protein location in heterochromatin" RELATED [GOC:mah] +is_a: GO:0032507 ! maintenance of protein location in cell +relationship: part_of GO:0097355 ! protein localization to heterochromatin +created_by: mah +creation_date: 2013-07-31T15:11:37Z + +[Term] +id: GO:1990154 +name: enzyme IIA-maltose transporter complex +namespace: cellular_component +def: "A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter." [GOC:bf, GOC:bhm, PMID:23770568] +synonym: "EIIA(Glc)-MalFGK2 complex" EXACT [PMID:23770568] +synonym: "EIIA(Glc)-maltose transporter complex" EXACT [PMID:23770568] +synonym: "maltose transporter inhibitor complex" RELATED [GOC:bhm] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +relationship: has_part GO:1990060 ! maltose transport complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2013-08-01T09:27:25Z + +[Term] +id: GO:1990155 +name: Dsc E3 ubiquitin ligase complex assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane." [GOC:mah, PMID:23760507] +synonym: "Dsc complex assembly" EXACT [PMID:23760507] +is_a: GO:0034622 ! cellular protein-containing complex assembly +created_by: mah +creation_date: 2013-08-01T14:19:19Z + +[Term] +id: GO:1990156 +name: DnaB-DnaG complex +namespace: cellular_component +def: "A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes." [GOC:bhm, PMID:14557266] +synonym: "DnaB-DnaG primosome complex" RELATED [GOC:bhm] +is_a: GO:0033202 ! DNA helicase complex +relationship: has_part GO:1990161 ! DnaB helicase complex +relationship: part_of GO:1990098 ! core primosome complex +created_by: bhm +creation_date: 2013-08-02T09:50:54Z + +[Term] +id: GO:1990157 +name: DnaA-DnaB-DnaC complex +namespace: cellular_component +def: "A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation." [GOC:bhm, PMID:20129058] +is_a: GO:1990099 ! pre-primosome complex +relationship: has_part GO:1990100 ! DnaB-DnaC complex +created_by: bhm +creation_date: 2013-08-02T11:42:27Z + +[Term] +id: GO:1990158 +name: DnaB-DnaC-DnaT-PriA-PriB complex +namespace: cellular_component +def: "A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired." [GOC:bhm, PMID:8663105] +synonym: "DnaB-DnaC-DnaT-PriA-PriB preprimosome" EXACT [PMID:8663105] +synonym: "phi-X174-type preprimosome" RELATED [PMID:8663105] +is_a: GO:1990099 ! pre-primosome complex +relationship: has_part GO:1990100 ! DnaB-DnaC complex +created_by: bhm +creation_date: 2013-08-02T11:52:55Z + +[Term] +id: GO:1990159 +name: DnaB-DnaC-DnaT-PriA-PriC complex +namespace: cellular_component +def: "A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired." [GOC:bhm, PMID:8663105] +synonym: "DnaB-DnaC-DnaT-PriA-PriC preprimosome" EXACT [PMID:8663105] +synonym: "phi-X174-type preprimosome" RELATED [PMID:8663105] +is_a: GO:1990099 ! pre-primosome complex +relationship: has_part GO:1990100 ! DnaB-DnaC complex +created_by: bhm +creation_date: 2013-08-02T11:58:16Z + +[Term] +id: GO:1990160 +name: DnaB-DnaC-Rep-PriC complex +namespace: cellular_component +def: "A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired." [GOC:bhm, PMID:19941825, PMID:8663105] +synonym: "DnaB-DnaC-Rep-PriC preprimosome" EXACT [PMID:8663105] +synonym: "phi-X174-type preprimosome" RELATED [PMID:8663105] +is_a: GO:1990099 ! pre-primosome complex +relationship: has_part GO:1990100 ! DnaB-DnaC complex +created_by: bhm +creation_date: 2013-08-02T12:05:25Z + +[Term] +id: GO:1990161 +name: DnaB helicase complex +namespace: cellular_component +def: "A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair." [GOC:bhm, PMID:17947583] +synonym: "DnaB hexamer" EXACT [GOC:bhm] +is_a: GO:0033202 ! DNA helicase complex +created_by: bhm +creation_date: 2013-08-02T15:55:48Z + +[Term] +id: GO:1990162 +name: histone deacetylase activity (H3-K4 specific) +namespace: molecular_function +def: "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein." [GOC:al, PMID:23771057] +is_a: GO:0004407 ! histone deacetylase activity +relationship: part_of GO:1990596 ! histone H3-K4 deacetylation +created_by: pr +creation_date: 2013-08-06T08:48:44Z + +[Term] +id: GO:1990164 +name: histone H2A phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of a phosphate group." [GOC:mah, PMID:23080121] +is_a: GO:0016572 ! histone phosphorylation +created_by: mah +creation_date: 2013-08-08T11:13:25Z + +[Term] +id: GO:1990165 +name: single-strand break-containing DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with damaged DNA containing single-strand breaks (SSBs)." [GOC:al, PMID:21984210] +synonym: "single-strand break-containing damaged DNA binding" EXACT [] +synonym: "SSB-containing DNA binding" EXACT [] +is_a: GO:0003684 ! damaged DNA binding +created_by: pr +creation_date: 2013-08-08T11:16:04Z + +[Term] +id: GO:1990166 +name: protein localization to site of double-strand break +namespace: biological_process +def: "Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred." [GOC:mah, PMID:23080121] +synonym: "protein localisation to site of double-strand break" EXACT [GOC:mah] +synonym: "protein localization to double-strand break site" EXACT [GOC:mah] +synonym: "protein localization to site of DSB" EXACT [GOC:mah] +is_a: GO:0034502 ! protein localization to chromosome +created_by: mah +creation_date: 2013-08-08T11:27:00Z + +[Term] +id: GO:1990167 +name: protein K27-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein." [PMID:23827681] +is_a: GO:0016579 ! protein deubiquitination +created_by: sp +creation_date: 2013-08-14T11:15:24Z + +[Term] +id: GO:1990168 +name: protein K33-linked deubiquitination +namespace: biological_process +def: "A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein." [PMID:23827681] +is_a: GO:0016579 ! protein deubiquitination +created_by: sp +creation_date: 2013-08-14T11:19:39Z + +[Term] +id: GO:1990169 +name: stress response to copper ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus." [GOC:kmv, PMID:23437011] +synonym: "response to copper ion stress" EXACT [] +synonym: "response to copper toxicity" RELATED [] +synonym: "stress response to copper" BROAD [] +is_a: GO:0046688 ! response to copper ion +is_a: GO:0097501 ! stress response to metal ion +created_by: pr +creation_date: 2013-08-14T12:52:05Z + +[Term] +id: GO:1990170 +name: stress response to cadmium ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus." [GOC:kmv] +synonym: "response to cadmium ion stress" EXACT [] +synonym: "response to cadmium toxicity" RELATED [] +synonym: "stress response to cadmium" BROAD [] +is_a: GO:0046686 ! response to cadmium ion +is_a: GO:0097501 ! stress response to metal ion +created_by: pr +creation_date: 2013-08-14T12:55:45Z + +[Term] +id: GO:1990171 +name: SCF complex disassembly in response to cadmium stress +namespace: biological_process +def: "The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress." [GOC:rb, PMID:23000173] +is_a: GO:0032984 ! protein-containing complex disassembly +relationship: part_of GO:0071276 ! cellular response to cadmium ion +created_by: rb +creation_date: 2013-08-15T22:38:06Z + +[Term] +id: GO:1990172 +name: G protein-coupled receptor catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor." [PMID:12142540, PMID:23954414] +synonym: "G-protein coupled receptor catabolic process" EXACT [] +is_a: GO:0032801 ! receptor catabolic process +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +created_by: sp +creation_date: 2013-08-22T10:16:58Z + +[Term] +id: GO:1990173 +name: protein localization to nucleoplasm +namespace: biological_process +alt_id: GO:0032066 +def: "A process in which a protein is transported to, or maintained in, a location within the nucleoplasm." [GOC:mah, PMID:22918952] +synonym: "nucleolus to nucleoplasm transport" RELATED [] +synonym: "protein localisation to nucleoplasm" EXACT [GOC:mah] +is_a: GO:0034504 ! protein localization to nucleus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14690 xsd:anyURI +created_by: mah +creation_date: 2013-08-23T15:01:16Z + +[Term] +id: GO:1990174 +name: phosphodiesterase decapping endonuclease activity +namespace: molecular_function +def: "Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA." [GOC:dgf, PMID:20802481] +synonym: "G(5')pppN pyrophosphatase activity" RELATED [] +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters +created_by: tb +creation_date: 2013-08-26T17:51:00Z + +[Term] +id: GO:1990175 +name: EH domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R." [GOC:hjd, PMID:11911876, PMID:21115825] +is_a: GO:0019904 ! protein domain specific binding +created_by: hjd +creation_date: 2013-08-27T20:14:56Z + +[Term] +id: GO:1990176 +name: MalFGK2 complex +namespace: cellular_component +def: "Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG." [GOC:bhm, PMID:19250913] +comment: The MalFGK2 complex lacks the maltose-binding subunit present in GO:1990060. +synonym: "MalF-MalG-MalK(2) complex" EXACT [GOC:bf] +synonym: "MalF-MalG-MalK-MalK complex" EXACT [GOC:bf] +synonym: "MalFGK(2) complex" EXACT [PMID:19250913] +synonym: "maltose transport complex, core subunit" EXACT [GOC:bhm] +synonym: "maltose transport MalFGK2 complex" EXACT [GOC:bhm] +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:1990060 ! maltose transport complex +created_by: bhm +creation_date: 2013-08-30T11:10:14Z + +[Term] +id: GO:1990177 +name: IHF-DNA complex +namespace: cellular_component +def: "A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid." [GOC:bhm, PMID:17097674] +synonym: "IHF complex" EXACT [GOC:bhm] +synonym: "IHFa-IHFb-DNA complex" EXACT [GOC:bhm] +is_a: GO:0032993 ! protein-DNA complex +is_a: GO:1990104 ! DNA bending complex +relationship: part_of GO:0043590 ! bacterial nucleoid +created_by: bhm +creation_date: 2013-08-30T12:22:54Z + +[Term] +id: GO:1990178 +name: HU-DNA complex +namespace: cellular_component +def: "A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure." [GOC:bhm, PMID:17360520] +synonym: "HU complex" BROAD [GOC:bhm] +is_a: GO:0032993 ! protein-DNA complex +is_a: GO:1990104 ! DNA bending complex +relationship: part_of GO:0043590 ! bacterial nucleoid +created_by: bhm +creation_date: 2013-08-30T13:06:53Z + +[Term] +id: GO:1990179 +name: protein localization to actomyosin contractile ring +namespace: biological_process +def: "A process in which a protein is transported to, or maintained at, the actomyosin contractile ring." [GOC:mah, PMID:23349808] +synonym: "protein localisation to actomyosin contractile ring" EXACT [] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:0072741 ! protein localization to cell division site +is_a: GO:1903119 ! protein localization to actin cytoskeleton +created_by: mah +creation_date: 2013-08-30T16:13:54Z + +[Term] +id: GO:1990180 +name: mitochondrial tRNA 3'-end processing +namespace: biological_process +def: "The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion." [GOC:mah, GOC:TermGenie, PMID:23928301] +synonym: "tRNA 3' processing in mitochondria" EXACT [GOC:TermGenie] +synonym: "tRNA 3' processing in mitochondrion" EXACT [GOC:TermGenie] +synonym: "tRNA 3'-end processing in mitochondria" EXACT [GOC:TermGenie] +is_a: GO:0000965 ! mitochondrial RNA 3'-end processing +is_a: GO:0042780 ! tRNA 3'-end processing +is_a: GO:0090646 ! mitochondrial tRNA processing +intersection_of: GO:0042780 ! tRNA 3'-end processing +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: mah +creation_date: 2013-08-30T16:17:36Z + +[Term] +id: GO:1990181 +name: acetyl-CoA biosynthetic process from pantothenate +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA." [GOC:mah, PMID:23091701] +synonym: "acetyl-CoA anabolism from pantothenate" EXACT [] +synonym: "acetyl-CoA formation from pantothenate" RELATED [] +synonym: "acetyl-CoA synthesis from pantothenate" RELATED [] +is_a: GO:0006085 ! acetyl-CoA biosynthetic process +is_a: GO:0015939 ! pantothenate metabolic process +created_by: mah +creation_date: 2013-08-30T16:20:44Z + +[Term] +id: GO:1990182 +name: exosomal secretion +namespace: biological_process +def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898] +synonym: "exosomal protein secretion" NARROW [PMID:18617898] +synonym: "exosomal secretory pathway" EXACT [PMID:18617898] +synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd] +synonym: "multi-vesicular body fusion with plasma membrane" EXACT [] +synonym: "secretion of exosome" EXACT [PMID:18617898] +is_a: GO:0006887 ! exocytosis +relationship: part_of GO:0097734 ! extracellular exosome biogenesis +property_value: RO:0002161 NCBITaxon:4890 +created_by: hjd +creation_date: 2013-09-04T21:08:14Z + +[Term] +id: GO:1990183 +name: lymphatic vascular process in circulatory system +namespace: biological_process +def: "A circulatory process that occurs at the level of the lymphatic vasculature." [PMID:21576390] +is_a: GO:0003018 ! vascular process in circulatory system +created_by: sl +creation_date: 2013-09-10T22:26:40Z + +[Term] +id: GO:1990184 +name: amino acid transport complex +namespace: cellular_component +def: "A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane." [GOC:kmv, PMID:14668347] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: jl +creation_date: 2013-09-11T15:02:16Z + +[Term] +id: GO:1990185 +name: regulation of lymphatic vascular permeability +namespace: biological_process +def: "Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid." [PMID:23897233] +is_a: GO:0043114 ! regulation of vascular permeability +is_a: GO:1990183 ! lymphatic vascular process in circulatory system +created_by: sl +creation_date: 2013-09-11T15:36:22Z + +[Term] +id: GO:1990186 +name: regulation of lymphatic vessel size +namespace: biological_process +def: "Any process that modulates the size of lymphatic vessels." [PMID:23897233] +synonym: "regulation of collecting lymphatic vessel size" NARROW [] +is_a: GO:0090066 ! regulation of anatomical structure size +is_a: GO:1990183 ! lymphatic vascular process in circulatory system +created_by: sl +creation_date: 2013-09-11T15:41:16Z + +[Term] +id: GO:1990187 +name: obsolete protein localization to mRNA +namespace: biological_process +def: "OBSOLETE. A process in which a protein is transported to, or maintained at mRNA." [GOC:rb, PMID:22890846] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "protein localization to mRNA" EXACT [] +is_obsolete: true +created_by: rb +creation_date: 2013-09-11T18:19:20Z + +[Term] +id: GO:1990188 +name: euchromatin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with euchromatin, a dispersed and relatively uncompacted form of chromatin." [GOC:vw, PMID:22431512] +is_a: GO:0003682 ! chromatin binding +created_by: tb +creation_date: 2013-09-11T19:18:38Z + +[Term] +id: GO:1990189 +name: peptide-serine-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide." [GOC:al, PMID:23912279] +is_a: GO:0004596 ! peptide alpha-N-acetyltransferase activity +created_by: tb +creation_date: 2013-09-11T20:13:40Z + +[Term] +id: GO:1990190 +name: peptide-glutamate-N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide." [GOC:al, PMID:23912279] +is_a: GO:0004596 ! peptide alpha-N-acetyltransferase activity +created_by: tb +creation_date: 2013-09-11T20:21:25Z + +[Term] +id: GO:1990191 +name: cobalamin transport complex +namespace: cellular_component +def: "Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD." [GOC:bhm, PMID:22569249] +synonym: "BtuCDF complex" EXACT [] +synonym: "cobalamin-transporting BtuCDF complex" EXACT [] +synonym: "vitamin B12 transport complex" EXACT [] +synonym: "vitamin B12-transporting BtuCDF complex" EXACT [] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +relationship: has_part GO:1990193 ! BtuCD complex +created_by: bhm +creation_date: 2013-09-12T14:20:19Z + +[Term] +id: GO:1990192 +name: collecting lymphatic vessel constriction +namespace: biological_process +def: "A decrease in the diameter of collecting lymphatic vessels." [PMID:23322290] +synonym: "lymphatic vessel myogenic constriction" EXACT [] +is_a: GO:1990186 ! regulation of lymphatic vessel size +created_by: sl +creation_date: 2013-09-12T14:46:05Z + +[Term] +id: GO:1990193 +name: BtuCD complex +namespace: cellular_component +def: "Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer." [GOC:bhm, PMID:22569249] +synonym: "BtuC-BtuD complex" EXACT [] +synonym: "cobalamin transport complex, core subunit" EXACT [] +synonym: "vitamin B12 transport complex, core subunit" EXACT [] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +created_by: bhm +creation_date: 2013-09-12T14:58:56Z + +[Term] +id: GO:1990194 +name: cytoplasmic U snRNP body assembly +namespace: biological_process +def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body." [PMID:19464282] +synonym: "U body assembly" RELATED [] +is_a: GO:0022618 ! ribonucleoprotein complex assembly +created_by: tb +creation_date: 2013-09-12T21:54:20Z + +[Term] +id: GO:1990195 +name: macrolide transmembrane transporter complex +namespace: cellular_component +def: "A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes." [GOC:bhm, PMID:10879525, PMID:18955484, PMID:19254725] +synonym: "AcrAB-TolC complex" NARROW [] +synonym: "MacAB-TolC complex" NARROW [] +synonym: "macrolide transporter" RELATED [] +synonym: "macrolide transporter complex" BROAD [] +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2013-09-23T11:22:26Z + +[Term] +id: GO:1990196 +name: MacAB-TolC complex +namespace: cellular_component +def: "The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC." [GOC:bhm, PMID:10879525, PMID:18955484, PMID:19254725] +synonym: "macrolide transporter MacAB-TolC complex" EXACT [] +is_a: GO:1990195 ! macrolide transmembrane transporter complex +created_by: bhm +creation_date: 2013-09-23T11:29:28Z + +[Term] +id: GO:1990197 +name: ATP-dependent methionine-importing complex +namespace: cellular_component +def: "An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner." [GOC:bhm, PMID:22095702] +synonym: "ATP-binding cassette (ABC) methionine importer complex" EXACT [] +synonym: "ATP-dependent methionine importer complex" EXACT [] +synonym: "ATP-dependent methionine importing complex" EXACT [] +synonym: "methionine transport complex" BROAD [] +synonym: "methionine transporter" RELATED [] +synonym: "methionine transporter complex" BROAD [] +synonym: "methionine transporter complex, ATP-dependent" BROAD [] +synonym: "MetNI complex" NARROW [] +synonym: "MetNI transport complex" NARROW [] +synonym: "MetNI transporter" RELATED [] +synonym: "MetNI transporter complex" NARROW [] +synonym: "MetNIQ complex" NARROW [] +synonym: "MetNIQ transport complex" NARROW [] +synonym: "MetNIQ transporter" RELATED [] +synonym: "MetNIQ transporter complex" RELATED [] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +is_a: GO:1902509 ! methionine-importing complex +created_by: bhm +creation_date: 2013-09-26T09:38:26Z + +[Term] +id: GO:1990198 +name: ModE complex +namespace: cellular_component +def: "A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism." [GOC:bhm, PMID:12581638] +synonym: "ModE dimer" EXACT [GOC:bhm] +is_a: GO:0005667 ! transcription regulator complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-01T07:28:52Z + +[Term] +id: GO:1990199 +name: MsbA transporter complex +namespace: cellular_component +def: "An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD)." [GOC:bhm, PMID:18024585] +synonym: "MsbA complex" EXACT [GOC:bhm] +synonym: "MsbA dimer" EXACT [GOC:bhm] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +created_by: bhm +creation_date: 2013-10-01T07:49:41Z + +[Term] +id: GO:1990200 +name: SsuD-SsuE complex +namespace: cellular_component +def: "A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation." [GOC:bhm, PMID:16997955] +synonym: "two-component alkanesulfonate monooxygenase system" RELATED [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990201 ! alkanesulfonate monooxygenase complex +relationship: has_part GO:1990202 ! FMN reductase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-03T12:59:26Z + +[Term] +id: GO:1990201 +name: alkanesulfonate monooxygenase complex +namespace: cellular_component +def: "A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer." [GOC:bhm, PMID:10480865, PMID:16997955] +synonym: "SsuD complex" NARROW [GOC:bhm] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-03T14:55:08Z + +[Term] +id: GO:1990202 +name: FMN reductase complex +namespace: cellular_component +def: "A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer." [GOC:bhm, PMID:10480865, PMID:16997955] +synonym: "flavin oxidoreductase complex, NAD(P)H-dependent" BROAD [GOC:bhm] +synonym: "FMN oxidoreductase complex, NAD(P)H-dependent" RELATED [GOC:bhm] +synonym: "FMN reductase complex, NAD(P)H-dependent" EXACT [GOC:bhm] +synonym: "SsuE complex" NARROW [GOC:bhm] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-03T15:07:20Z + +[Term] +id: GO:1990203 +name: MdtBC Complex +namespace: cellular_component +def: "A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane." [GOC:bhm, PMID:20038594] +synonym: "multidrug efflux pump MdtBC" EXACT [GOC:bhm] +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2013-10-04T21:22:18Z + +[Term] +id: GO:1990204 +name: oxidoreductase complex +namespace: cellular_component +def: "Any protein complex that possesses oxidoreductase activity." [GOC:bhm, PMID:18982432] +subset: goslim_metagenomics +synonym: "oxidation-reduction complex" EXACT [] +synonym: "redox complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2013-10-07T08:24:47Z + +[Term] +id: GO:1990205 +name: taurine dioxygenase complex +namespace: cellular_component +def: "A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD." [GOC:bhm, PMID:12741810] +synonym: "2-aminoethanesulfonate dioxygenase complex" EXACT [] +synonym: "alpha-ketoglutarate-dependent taurine dioxygenase complex" EXACT [] +synonym: "TauD complex" NARROW [] +is_a: GO:1990204 ! oxidoreductase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-07T13:03:15Z + +[Term] +id: GO:1990206 +name: jasmonyl-Ile conjugate hydrolase activity +namespace: molecular_function +def: "Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine." [PMID:23943861] +synonym: "JA-Ile hydrolase" RELATED [] +is_a: GO:0016810 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds +created_by: tb +creation_date: 2013-10-07T18:37:49Z + +[Term] +id: GO:1990207 +name: EmrE multidrug transporter complex +namespace: cellular_component +def: "A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer." [GOC:bhm, PMID:18024586] +synonym: "EmrE complex" NARROW [] +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1902495 ! transmembrane transporter complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2013-10-08T08:37:52Z + +[Term] +id: GO:1990208 +name: positive regulation by symbiont of RNA levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:12182338, PMID:18703740] +is_a: GO:0052018 ! modulation by symbiont of RNA levels in host +created_by: ml +creation_date: 2013-10-08T13:31:41Z + +[Term] +id: GO:1990209 +name: negative regulation by symbiont of RNA levels in host +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:18703740] +is_a: GO:0052018 ! modulation by symbiont of RNA levels in host +created_by: ml +creation_date: 2013-10-09T18:09:33Z + +[Term] +id: GO:1990210 +name: positive regulation by symbiont of indole acetic acid levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:18056646] +synonym: "positive regulation by symbiont of auxin levels in host" EXACT [] +synonym: "positive regulation by symbiont of IAA levels in host" EXACT [] +is_a: GO:0044032 ! modulation by symbiont of indole acetic acid levels in host +is_a: GO:0052024 ! positive regulation by symbiont of hormone or growth regulator levels in host +created_by: ml +creation_date: 2013-10-09T18:54:11Z + +[Term] +id: GO:1990211 +name: positive regulation by symbiont of jasmonic acid levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:14617079, PMID:16553894] +is_a: GO:0052022 ! modulation by symbiont of jasmonic acid levels in host +is_a: GO:0052024 ! positive regulation by symbiont of hormone or growth regulator levels in host +created_by: ml +creation_date: 2013-10-09T18:58:37Z + +[Term] +id: GO:1990212 +name: positive regulation by symbiont of ethylene levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:16167902] +is_a: GO:0052021 ! modulation by symbiont of ethylene levels in host +is_a: GO:0052024 ! positive regulation by symbiont of hormone or growth regulator levels in host +created_by: ml +creation_date: 2013-10-09T19:03:10Z + +[Term] +id: GO:1990213 +name: negative regulation by symbiont of salicylic acid levels in host +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:ml, PMID:17722699, PMID:20565685] +is_a: GO:0052023 ! modulation by symbiont of salicylic acid levels in host +is_a: GO:0052024 ! positive regulation by symbiont of hormone or growth regulator levels in host +created_by: ml +creation_date: 2013-10-09T19:06:19Z + +[Term] +id: GO:1990214 +name: obsolete negative regulation by symbiont of host protein levels +namespace: biological_process +def: "OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:16840699, PMID:22233353] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true +created_by: ml +creation_date: 2013-10-10T15:39:45Z + +[Term] +id: GO:1990215 +name: negative regulation by symbiont of host intracellular transport +namespace: biological_process +def: "Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:22319451] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0052038 ! modulation by symbiont of host intracellular transport +intersection_of: GO:0044068 ! modulation by symbiont of host cellular process +intersection_of: negatively_regulates GO:0046907 ! intracellular transport +created_by: ml +creation_date: 2013-10-10T15:42:22Z + +[Term] +id: GO:1990216 +name: positive regulation by symbiont of host transcription +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21994350] +is_a: GO:0052026 ! modulation by symbiont of host transcription +created_by: ml +creation_date: 2013-10-10T15:45:17Z + +[Term] +id: GO:1990217 +name: suppression by symbiont of host phytoalexin production +namespace: biological_process +def: "Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21402357] +synonym: "negative regulation by symbiont of host phytoalexin production" EXACT [] +is_a: GO:0052165 ! symbiont defense to host-produced phytoalexin +created_by: ml +creation_date: 2013-10-10T15:49:33Z + +[Term] +id: GO:1990218 +name: positive regulation by symbiont of abscisic acid levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:17304219] +is_a: GO:0075343 ! modulation by symbiont of abscisic acid levels in host +created_by: ml +creation_date: 2013-10-10T15:54:10Z + +[Term] +id: GO:1990219 +name: obsolete positive regulation by symbiont of host protein levels +namespace: biological_process +def: "OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:20615948] +comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms. +is_obsolete: true +created_by: ml +creation_date: 2013-10-10T17:26:03Z + +[Term] +id: GO:1990220 +name: GroEL-GroES complex +namespace: cellular_component +def: "Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins." [GOC:bhm, PMID:15313620] +synonym: "bacterial chaperonin ATPase complex" RELATED [] +synonym: "bacterial chaperonin complex" RELATED [] +is_a: GO:0016465 ! chaperonin ATPase complex +created_by: bhm +creation_date: 2013-10-11T09:20:01Z + +[Term] +id: GO:1990221 +name: L-cysteine desulfurase complex +namespace: cellular_component +def: "A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer." [GOC:bhm, PMID:11827487] +synonym: "IscS" NARROW [GOC:bhm, GOC:dph] +synonym: "NIFS" NARROW [GOC:bhm, GOC:dph] +synonym: "NifS" NARROW [GOC:bhm, GOC:dph] +synonym: "SufS complex" NARROW [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-10-11T15:36:34Z + +[Term] +id: GO:1990222 +name: ProVWX complex +namespace: cellular_component +def: "The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions." [GOC:bhm, PMID:23249124] +synonym: "ATP-binding cassette (ABC) transporter complex ProVWX" EXACT [] +is_a: GO:0043190 ! ATP-binding cassette (ABC) transporter complex +created_by: bhm +creation_date: 2013-10-16T09:09:17Z + +[Term] +id: GO:1990223 +name: positive regulation by symbiont of cytokinin levels in host +namespace: biological_process +def: "Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:24124900] +is_a: GO:0052024 ! positive regulation by symbiont of hormone or growth regulator levels in host +created_by: ml +creation_date: 2013-10-16T15:27:27Z + +[Term] +id: GO:1990224 +name: NMN phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate." [GOC:rb, PMID:21349851, RHEA:30815] +synonym: "beta-nicotinamide D-ribonucleotide phosphatase activity" EXACT [] +synonym: "nicotinamide mononucleotide phosphatase activity" EXACT [] +is_a: GO:0016791 ! phosphatase activity +created_by: rb +creation_date: 2013-10-21T18:03:41Z + +[Term] +id: GO:1990225 +name: rhoptry neck +namespace: cellular_component +def: "Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion." [GOC:giardia, GOC:pr, PMID:23499754, PMID:23937520, PMID:24002067, PMID:24070999] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020008 ! rhoptry +created_by: pr +creation_date: 2013-11-03T14:19:26Z + +[Term] +id: GO:1990226 +name: histone methyltransferase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone methyltransferase enzyme." [GOC:ame, GOC:BHF, PMID:19486527] +is_a: GO:0019899 ! enzyme binding +created_by: pr +creation_date: 2013-11-07T11:59:58Z + +[Term] +id: GO:1990227 +name: paranodal junction maintenance +namespace: biological_process +def: "The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath." [GOC:pr, PMID:24011083] +synonym: "axoglial septate junction maintenance" EXACT [] +synonym: "paranodal axoglial junction maintenance" EXACT [] +synonym: "paranodal septate maintenance" EXACT [] +is_a: GO:0045217 ! cell-cell junction maintenance +created_by: pr +creation_date: 2013-11-07T20:01:46Z + +[Term] +id: GO:1990228 +name: sulfurtransferase complex +namespace: cellular_component +def: "A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor)." [GOC:bhm, PMID:17350958] +synonym: "SufE complex" NARROW [GOC:bhm] +synonym: "SufE dimer" NARROW [GOC:bhm] +synonym: "sulfur transfer complex" EXACT [GOC:bhm] +synonym: "ThiF-ThiS complex" RELATED [GOC:bhm] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-11-12T09:08:23Z + +[Term] +id: GO:1990229 +name: iron-sulfur cluster assembly complex +namespace: cellular_component +def: "A protein complex capable of assembling an iron-sulfur (Fe-S) cluster." [GOC:bhm, PMID:17350958] +synonym: "Fe-S cluster assembly complex" NARROW [GOC:bhm] +synonym: "SufBCD complex" NARROW [GOC:bhm] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-11-12T09:15:03Z + +[Term] +id: GO:1990230 +name: iron-sulfur cluster transfer complex +namespace: cellular_component +def: "A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor)." [GOC:bhm, PMID:19810706] +synonym: "Fe-S cluster transfer complex" EXACT [GOC:bhm] +synonym: "IscA complex" NARROW [GOC:bhm] +synonym: "SufA complex" NARROW [GOC:bhm] +synonym: "SufA dimer" NARROW [GOC:bhm] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-11-12T09:17:40Z + +[Term] +id: GO:1990231 +name: STING complex +namespace: cellular_component +def: "A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response." [GOC:bhm, PMID:22705373, PMID:23706668, PMID:23910378] +synonym: "stimulator of interferon genes complex" EXACT [GOC:bhm, PMID:22705373, PMID:23910378] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0030659 ! cytoplasmic vesicle membrane +created_by: bhm +creation_date: 2013-11-12T10:58:34Z + +[Term] +id: GO:1990232 +name: phosphomannomutase complex +namespace: cellular_component +def: "A protein complex capable of phosphomannomutase activity." [GOC:bhm, PMID:16540464] +synonym: "PMM-1 complex" NARROW [GOC:bhm] +synonym: "PMM-1 dimer" NARROW [GOC:bhm] +synonym: "PMM-2 complex" NARROW [GOC:bhm] +synonym: "PMM-2 dimer" NARROW [GOC:bhm] +is_a: GO:1990233 ! intramolecular phosphotransferase complex +created_by: bhm +creation_date: 2013-11-12T13:05:54Z + +[Term] +id: GO:1990233 +name: intramolecular phosphotransferase complex +namespace: cellular_component +def: "A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule." [GOC:bhm, PMID:16540464] +is_a: GO:1902494 ! catalytic complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-11-12T13:10:12Z + +[Term] +id: GO:1990234 +name: transferase complex +namespace: cellular_component +def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464] +is_a: GO:1902494 ! catalytic complex +created_by: bhm +creation_date: 2013-11-12T13:20:12Z + +[Term] +id: GO:1990235 +name: diamine N-acetyltransferase complex +namespace: cellular_component +def: "A protein complex which is capable of diamine N-acetyltransferase activity." [GOC:bhm, PMID:8077207] +synonym: "SAT complex" NARROW [GOC:bhm] +synonym: "SAT tetramer" NARROW [GOC:bhm] +synonym: "spermidine acetyltransferase complex" NARROW [GOC:bhm] +is_a: GO:1902493 ! acetyltransferase complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2013-11-13T16:29:45Z + +[Term] +id: GO:1990236 +name: proteasome core complex import into nucleus +namespace: biological_process +def: "The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus." [GOC:dos, GOC:rb, PMID:23982732] +is_a: GO:0006606 ! protein import into nucleus +is_a: GO:0031503 ! protein-containing complex localization +created_by: rb +creation_date: 2013-11-14T23:27:24Z + +[Term] +id: GO:1990237 +name: sequestration of proteasome core complex in proteasome storage granule +namespace: biological_process +def: "Any process where the proteasome core particle (CP) is sequestered in the protein storage granule in the cytoplasm." [GOC:rb, PMID:23982732] +is_a: GO:0098545 ! maintenance of protein complex location in cytoplasm +relationship: occurs_in GO:0034515 ! proteasome storage granule +created_by: rb +creation_date: 2013-11-14T23:29:41Z + +[Term] +id: GO:1990238 +name: double-stranded DNA endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks." [GOC:PG, PMID:22885404] +synonym: "dsDNA-specific endodeoxyribonuclease activity" RELATED [] +is_a: GO:0004520 ! endodeoxyribonuclease activity +created_by: pg +creation_date: 2013-11-15T00:59:42Z + +[Term] +id: GO:1990239 +name: steroid hormone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a steroid hormone." [GOC:ln] +is_a: GO:0005496 ! steroid binding +is_a: GO:0042562 ! hormone binding +created_by: pr +creation_date: 2013-11-15T09:26:18Z + +[Term] +id: GO:1990241 +name: obsolete nucleotide binding complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6)." [GOC:bhm, PMID:23910378] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "nucleotide binding complex" EXACT [] +is_obsolete: true +created_by: bhm +creation_date: 2013-11-22T16:22:07Z + +[Term] +id: GO:1990242 +name: obsolete innate immune response complex +namespace: cellular_component +def: "OBSOLETE. A protein complex involved in the innate immune response." [GOC:bhm, PMID:23910378] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "innate immune response complex" EXACT [] +is_obsolete: true +created_by: bhm +creation_date: 2013-11-26T13:36:52Z + +[Term] +id: GO:1990243 +name: atf1-pcr1 complex +namespace: cellular_component +def: "A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE)." [PMID:24224056] +is_a: GO:0035976 ! transcription factor AP-1 complex +created_by: al +creation_date: 2013-11-28T11:40:28Z + +[Term] +id: GO:1990244 +name: histone kinase activity (H2A-T120 specific) +namespace: molecular_function +def: "Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A." [PMID:24140421] +synonym: "histone threonine kinase activity (H2A-T120 specific)" EXACT [] +is_a: GO:0035184 ! histone threonine kinase activity +relationship: part_of GO:1990245 ! histone H2A-T120 phosphorylation +created_by: sp +creation_date: 2013-12-04T06:38:32Z + +[Term] +id: GO:1990245 +name: histone H2A-T120 phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone." [PMID:24140421] +synonym: "histone H2A phosphorylation at T120" EXACT [] +synonym: "histone H2AT120 phosphorylation" EXACT [] +is_a: GO:0035405 ! histone-threonine phosphorylation +is_a: GO:1990164 ! histone H2A phosphorylation +created_by: sp +creation_date: 2013-12-04T06:41:30Z + +[Term] +id: GO:1990246 +name: uniplex complex +namespace: cellular_component +def: "A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE." [PMID:24231807] +synonym: "mitochondrial uniporter complex" EXACT [] +synonym: "mitochondrial uniporter holocomplex" EXACT [] +is_a: GO:0034704 ! calcium channel complex +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +created_by: sp +creation_date: 2013-12-04T06:44:35Z + +[Term] +id: GO:1990247 +name: N6-methyladenosine-containing RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs." [PMID:22575960, PMID:24284625] +is_a: GO:0003723 ! RNA binding +created_by: sp +creation_date: 2013-12-04T06:55:29Z + +[Term] +id: GO:1990248 +name: regulation of transcription from RNA polymerase II promoter in response to DNA damage +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage." [PMID:15660129] +is_a: GO:0006974 ! cellular response to DNA damage stimulus +is_a: GO:0043618 ! regulation of transcription from RNA polymerase II promoter in response to stress +created_by: pg +creation_date: 2013-12-04T13:28:04Z + +[Term] +id: GO:1990249 +name: nucleotide-excision repair, DNA damage recognition complex +namespace: cellular_component +def: "A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex." [GOC:bhm, PMID:22331906] +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2013-12-05T16:26:51Z + +[Term] +id: GO:1990250 +name: transcription-coupled nucleotide-excision repair, DNA damage recognition complex +namespace: cellular_component +def: "A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex." [GOC:bhm, PMID:22331906] +is_a: GO:1990249 ! nucleotide-excision repair, DNA damage recognition complex +created_by: bhm +creation_date: 2013-12-05T16:28:45Z + +[Term] +id: GO:1990251 +name: nuclear exosome focus +namespace: cellular_component +def: "An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome." [GOC:al, GOC:vw, PMID:16823445, PMID:23980030, PMID:32012158] +synonym: "Mmi1 nuclear focus" EXACT [] +synonym: "nuclear body" RELATED [] +is_a: GO:0016604 ! nuclear body +relationship: has_part GO:0000176 ! nuclear exosome (RNase complex) +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19063 xsd:anyURI +created_by: al +creation_date: 2013-12-09T12:07:46Z + +[Term] +id: GO:1990252 +name: Syp1 complex +namespace: cellular_component +def: "A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis." [GOC:bhm, PMID:19713939] +synonym: "Syp1 dimer" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0045334 ! clathrin-coated endocytic vesicle +created_by: bhm +creation_date: 2013-12-09T14:43:00Z + +[Term] +id: GO:1990253 +name: cellular response to leucine starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine." [PMID:19033384] +xref: CHEBI:25017 +is_a: GO:0034198 ! cellular response to amino acid starvation +created_by: al +creation_date: 2013-12-10T11:55:10Z + +[Term] +id: GO:1990254 +name: keratin filament binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells." [GOC:krc, PMID:6170061] +is_a: GO:0019215 ! intermediate filament binding +created_by: tb +creation_date: 2013-12-13T22:05:25Z + +[Term] +id: GO:1990255 +name: subsynaptic reticulum organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane." [PMID:21041451] +is_a: GO:0006996 ! organelle organization +created_by: tb +creation_date: 2013-12-13T23:05:21Z + +[Term] +id: GO:1990256 +name: signal clustering +namespace: biological_process +def: "Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response." [GOC:als, PMID:12011072, PMID:15603739] +synonym: "ligand clustering" BROAD [GOC:als] +is_a: GO:0009966 ! regulation of signal transduction +created_by: tb +creation_date: 2013-12-18T01:13:59Z + +[Term] +id: GO:1990257 +name: piccolo-bassoon transport vesicle +namespace: cellular_component +def: "A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon." [GOC:dr, PMID:21569270] +synonym: "PTV" RELATED [] +is_a: GO:0031410 ! cytoplasmic vesicle +property_value: RO:0002161 NCBITaxon:4895 +created_by: pr +creation_date: 2013-12-19T14:12:09Z + +[Term] +id: GO:1990258 +name: histone glutamine methylation +namespace: biological_process +def: "The modification of a histone by addition of a methyl group to an glutamine residue." [PMID:24352239] +is_a: GO:0016571 ! histone methylation +is_a: GO:0018364 ! peptidyl-glutamine methylation +created_by: sp +creation_date: 2014-01-02T15:08:02Z + +[Term] +id: GO:1990259 +name: histone-glutamine methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine." [PMID:24352239] +is_a: GO:0036009 ! protein-glutamine N-methyltransferase activity +is_a: GO:0042054 ! histone methyltransferase activity +created_by: sp +creation_date: 2014-01-02T15:10:29Z + +[Term] +id: GO:1990260 +name: negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling." [PMID:24006488] +is_a: GO:0010621 ! negative regulation of transcription by transcription factor localization +relationship: part_of GO:0072423 ! response to DNA damage checkpoint signaling +created_by: al +creation_date: 2014-01-07T17:10:11Z + +[Term] +id: GO:1990261 +name: pre-mRNA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA)." [GOC:rb, PMID:22844259] +synonym: "pre-mRNA decay" EXACT [] +synonym: "unspliced RNA decay" EXACT [] +is_a: GO:0006401 ! RNA catabolic process +created_by: rb +creation_date: 2014-01-07T23:06:44Z + +[Term] +id: GO:1990262 +name: anti-Mullerian hormone signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:hjd, PMID:23624077] +comment: An example of this is Amhr2 in M. musculus (Q8K592) a receptor for anti-mullerian hormone, described in PMID:23624077. +is_a: GO:0007166 ! cell surface receptor signaling pathway +created_by: hjd +creation_date: 2014-01-08T20:42:09Z + +[Term] +id: GO:1990263 +name: spore wall assembly MAPK cascade +namespace: biological_process +def: "A MAPK cascade that occurs as a result of deprivation of nourishment." [GOC:al, PMID:7501024] +synonym: "MAPK cascade in response to starvation" EXACT [] +synonym: "MAPK cascade involved in nutrient response signaling" EXACT [GOC:al] +is_a: GO:0009267 ! cellular response to starvation +is_a: GO:0051403 ! stress-activated MAPK cascade +created_by: al +creation_date: 2014-01-09T12:27:52Z + +[Term] +id: GO:1990264 +name: peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity +namespace: biological_process +def: "Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity." [PMID:7501024] +is_a: GO:0035335 ! peptidyl-tyrosine dephosphorylation +relationship: part_of GO:0006469 ! negative regulation of protein kinase activity +created_by: al +creation_date: 2014-01-09T14:28:41Z + +[Term] +id: GO:1990265 +name: platelet-derived growth factor complex +namespace: cellular_component +def: "A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD)." [GOC:bhm, PMID:11331882] +comment: An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay). +synonym: "PDGF complex" RELATED [] +synonym: "PDGF-AA dimer" NARROW [] +synonym: "PDGF-AB dimer" NARROW [] +synonym: "PDGF-BB dimer" NARROW [] +synonym: "PDGF-CC dimer" NARROW [] +synonym: "PDGF-DD dimer" NARROW [] +xref: IntAct:EBI-2881436 +xref: IntAct:EBI-2881443 +xref: IntAct:EBI-2881451 +is_a: GO:0036454 ! growth factor complex +created_by: bhm +creation_date: 2014-01-09T16:09:11Z + +[Term] +id: GO:1990266 +name: neutrophil migration +namespace: biological_process +def: "The movement of a neutrophil within or between different tissues and organs of the body." [PMID:1826836] +is_a: GO:0097530 ! granulocyte migration +created_by: sl +creation_date: 2014-01-10T00:17:47Z + +[Term] +id: GO:1990267 +name: response to transition metal nanoparticle +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle." [PMID:23150627] +synonym: "response to colloidal metal" RELATED [] +synonym: "response to neutral metal atoms" RELATED [] +is_a: GO:0042221 ! response to chemical +created_by: sl +creation_date: 2014-01-10T17:16:41Z + +[Term] +id: GO:1990268 +name: response to gold nanoparticle +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus." [PMID:23150627] +is_a: GO:1990267 ! response to transition metal nanoparticle +created_by: sl +creation_date: 2014-01-10T17:37:34Z + +[Term] +id: GO:1990269 +name: RNA polymerase II C-terminal domain phosphoserine binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II." [GOC:di, PMID:22796944] +synonym: "RNA Pol II C-terminal domain phosphoserine binding" EXACT [GOC:di] +synonym: "RNAP II C-terminal domain phosphoserine binding" EXACT [] +is_a: GO:0050815 ! phosphoserine residue binding +is_a: GO:0099122 ! RNA polymerase II C-terminal domain binding +created_by: tb +creation_date: 2014-01-11T00:34:59Z + +[Term] +id: GO:1990270 +name: platelet-derived growth factor receptor-ligand complex +namespace: cellular_component +def: "A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes." [GOC:bhm, PMID:11331882] +comment: An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay). +synonym: "PDGF complex" BROAD [] +synonym: "PDGF receptor-ligand complex" EXACT [] +synonym: "PDGF-AA-receptor alpha complex" NARROW [] +synonym: "PDGF-AB-receptor alpha complex" NARROW [] +synonym: "PDGF-AB-receptor beta complex" NARROW [] +synonym: "PDGF-BB-receptor alpha complex" NARROW [] +synonym: "PDGF-BB-receptor alpha-beta complex" NARROW [] +synonym: "PDGF-BB-receptor beta complex" NARROW [] +synonym: "PDGF-CC-receptor alpha complex" NARROW [] +synonym: "PDGF-CC-receptor alpha-beta complex" NARROW [] +synonym: "PDGF-CC-receptor beta complex" NARROW [] +synonym: "PDGF-DD-receptor alpha-beta complex" NARROW [] +synonym: "PDGF-DD-receptor beta complex" NARROW [] +synonym: "receptor-ligand complex" BROAD [] +xref: IntAct:EBI-9080360 +is_a: GO:0098797 ! plasma membrane protein complex +relationship: has_part GO:0043235 ! receptor complex +relationship: has_part GO:1990265 ! platelet-derived growth factor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2014-01-14T11:12:22Z + +[Term] +id: GO:1990271 +name: obsolete anti-Mullerian hormone +namespace: molecular_function +def: "OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity." [GOC:hjd, PMID:23624077] +comment: An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077. +synonym: "anti-Mullerian hormone" EXACT [] +is_obsolete: true +created_by: hjd +creation_date: 2014-01-14T20:38:39Z + +[Term] +id: GO:1990272 +name: anti-Mullerian hormone receptor activity +namespace: molecular_function +def: "Combining with anti-Mullerian hormone to initiate a change in cell activity." [GOC:hjd, PMID:23624077] +comment: An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077. +is_a: GO:0016500 ! protein-hormone receptor activity +relationship: part_of GO:1990262 ! anti-Mullerian hormone signaling pathway +created_by: hjd +creation_date: 2014-01-14T21:41:35Z + +[Term] +id: GO:1990273 +name: snRNA 5'-end processing +namespace: biological_process +def: "Any process involved in forming the mature 5' end of an snRNA molecule." [PMID:22740346] +is_a: GO:0016180 ! snRNA processing +is_a: GO:0034471 ! ncRNA 5'-end processing +created_by: al +creation_date: 2014-01-15T15:32:06Z + +[Term] +id: GO:1990274 +name: mitotic actomyosin contractile ring disassembly +namespace: biological_process +def: "Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle." [PMID:14602073, PMID:22891673] +synonym: "mitotic actomyosin ring disassembly" RELATED [] +synonym: "mitotic CAR disassembly" EXACT [] +synonym: "mitotic constriction ring disassembly" RELATED [] +synonym: "mitotic contractile actomyosin ring disassembly" EXACT [] +synonym: "mitotic cytokinetic ring disassembly" RELATED [] +is_a: GO:1902410 ! mitotic cytokinetic process +is_a: GO:1902621 ! actomyosin contractile ring disassembly +intersection_of: GO:1902621 ! actomyosin contractile ring disassembly +intersection_of: part_of GO:0000281 ! mitotic cytokinesis +created_by: mah +creation_date: 2014-01-16T10:25:42Z + +[Term] +id: GO:1990275 +name: preribosome binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a preribosome." [GOC:di, PMID:22735702] +is_a: GO:0043021 ! ribonucleoprotein complex binding +created_by: tb +creation_date: 2014-01-16T19:14:50Z + +[Term] +id: GO:1990276 +name: RNA 5'-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule." [GOC:al, GOC:vw, PMID:22740346] +is_a: GO:0008173 ! RNA methyltransferase activity +is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity +created_by: pr +creation_date: 2014-01-28T09:44:16Z + +[Term] +id: GO:1990277 +name: parasexual conjugation with cellular fusion +namespace: biological_process +def: "A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans." [GOC:di] +synonym: "mating" BROAD [] +is_a: GO:0000746 ! conjugation +is_a: GO:0140253 ! cell-cell fusion +created_by: pr +creation_date: 2014-01-28T10:30:20Z + +[Term] +id: GO:1990278 +name: obsolete positive regulation of MBF transcription factor activity +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF." [PMID:11795845] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "positive regulation of MBF transcription factor activity" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-01-29T14:43:44Z + +[Term] +id: GO:1990279 +name: obsolete negative regulation of MBF transcription factor activity +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF." [PMID:24006488] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "negative regulation of MBF transcription factor activity" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-01-29T14:46:52Z + +[Term] +id: GO:1990280 +name: RNA localization to chromatin +namespace: biological_process +def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262] +synonym: "RNA localisation to chromatin" EXACT [] +is_a: GO:0006403 ! RNA localization +created_by: mah +creation_date: 2014-01-30T15:55:34Z + +[Term] +id: GO:1990281 +name: efflux pump complex +namespace: cellular_component +def: "A protein complex that is capable of efflux transmembrane transporter activity." [GOC:dos, PMID:21556065, PMID:9417051] +synonym: "efflux pump" EXACT [] +synonym: "efflux transmembrane transporter complex" EXACT [] +is_a: GO:1902495 ! transmembrane transporter complex +created_by: tt +creation_date: 2014-01-31T08:19:53Z + +[Term] +id: GO:1990294 +name: peptidyl-threonine trans-autophosphorylation +namespace: biological_process +def: "The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer." [PMID:19357077] +is_a: GO:0018107 ! peptidyl-threonine phosphorylation +is_a: GO:0036290 ! protein trans-autophosphorylation +created_by: al +creation_date: 2014-02-05T12:42:46Z + +[Term] +id: GO:1990295 +name: post-anaphase microtubule array +namespace: cellular_component +def: "A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center." [PMID:11792817, PMID:17072892, PMID:9601091] +comment: The best-characterized example is found in the fission yeast Schizosaccharomyces pombe. The eMTOC is cortical, but the post-anaphase array microtubules are not exclusively cortical. +synonym: "PAA" EXACT [] +synonym: "post-anaphase array" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0000923 ! equatorial microtubule organizing center +relationship: part_of GO:0015630 ! microtubule cytoskeleton +created_by: mah +creation_date: 2014-02-20T13:54:23Z + +[Term] +id: GO:1990297 +name: renal amino acid absorption +namespace: biological_process +def: "A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures." [GOC:hjd, PMID:1526373] +is_a: GO:0070293 ! renal absorption +created_by: hjd +creation_date: 2014-02-25T22:05:57Z + +[Term] +id: GO:1990298 +name: bub1-bub3 complex +namespace: cellular_component +def: "Protein complex that associates with the kinetochores." [PMID:22521786] +is_a: GO:0032991 ! protein-containing complex +created_by: al +creation_date: 2014-02-26T09:23:04Z + +[Term] +id: GO:1990299 +name: Bub1-Bub3 complex localization to kinetochore +namespace: biological_process +def: "A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore." [PMID:22521786] +is_a: GO:0034501 ! protein localization to kinetochore +is_a: GO:0034629 ! cellular protein-containing complex localization +created_by: al +creation_date: 2014-02-26T09:29:13Z + +[Term] +id: GO:1990300 +name: cellulosome binding +namespace: molecular_function +alt_id: GO:1990301 +def: "Interacting selectively and non-covalently with the cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides." [GOC:mengo_curators, PMID:11893054, PMID:15197390] +synonym: "scaffoldin complex binding" NARROW [] +is_a: GO:0005488 ! binding +creation_date: 2014-02-26T22:41:22Z + +[Term] +id: GO:1990302 +name: Bre1-Rad6 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis." [GOC:bhm, PMID:19531475] +comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay). +synonym: "Bre1-Rad6 complex" EXACT [] +xref: IntAct:EBI-9102228 +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2014-02-28T16:50:34Z + +[Term] +id: GO:1990303 +name: UBR1-RAD6 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes." [GOC:bhm, PMID:19531475] +comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay). +synonym: "UBR1-RAD6 complex" EXACT [] +xref: IntAct:EBI-9103673 +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2014-03-03T21:43:49Z + +[Term] +id: GO:1990304 +name: MUB1-RAD6-UBR2 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme." [GOC:bhm, PMID:18070918] +comment: This complex has been identified in Saccharomyces cerevisiae (UniProt symbol P19812) - see PMID:18070918. +xref: IntAct:EBI-9117531 +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2014-03-03T21:54:21Z + +[Term] +id: GO:1990305 +name: RAD6-UBR2 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation." [GOC:bhm, PMID:15504724] +comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:15504724 +synonym: "RAD6-UBR2 complex" EXACT [] +xref: IntAct:EBI-9116509 +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2014-03-03T22:14:32Z + +[Term] +id: GO:1990306 +name: RSP5-BUL ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation." [GOC:bhm, PMID:9931424] +comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424 +synonym: "RSP5-BUL1 complex" EXACT [] +synonym: "RSP5-BUL2 complex" RELATED [] +xref: IntAct:EBI-9105217 +xref: IntAct:EBI-9105295 +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005622 ! intracellular +created_by: bhm +creation_date: 2014-03-03T22:53:01Z + +[Term] +id: GO:1990308 +name: type-I dockerin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T03:10:37Z + +[Term] +id: GO:1990309 +name: type-II dockerin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T03:16:49Z + +[Term] +id: GO:1990310 +name: type-III dockerin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T03:22:36Z + +[Term] +id: GO:1990311 +name: type-I cohesin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T04:47:31Z + +[Term] +id: GO:1990312 +name: type-II cohesin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T04:51:07Z + +[Term] +id: GO:1990313 +name: type-III cohesin domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain." [GOC:mengo_curators, PMID:23195689, PMID:24080387] +is_a: GO:0019904 ! protein domain specific binding +created_by: tt +creation_date: 2014-03-07T04:58:07Z + +[Term] +id: GO:1990314 +name: cellular response to insulin-like growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus." [PMID:20042609] +synonym: "cellular response to insulin-like growth factor" EXACT [] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +created_by: sl +creation_date: 2014-03-07T19:38:21Z + +[Term] +id: GO:1990315 +name: Mcs4 RR-MAPKKK complex +namespace: cellular_component +def: "A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress." [PMID:24255738] +comment: In S. pombe it consists of Mpr1, Tdh1, Mcs4, Win1, Wis4 and Wis1. +is_a: GO:0032991 ! protein-containing complex +created_by: al +creation_date: 2014-03-14T09:59:45Z + +[Term] +id: GO:1990316 +name: Atg1/ULK1 kinase complex +namespace: cellular_component +alt_id: GO:0034273 +alt_id: GO:0070969 +def: "A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation." [GOC:bhm, GOC:DOS, GOC:rb, PMID:15743910, PMID:19211835, PMID:19258318, PMID:19597335, PMID:22885598] +synonym: "ATG1 kinase complex" EXACT [] +synonym: "ATG1-ATG13 complex" EXACT [] +synonym: "ATG1/ULK1 signaling complex" EXACT [] +synonym: "Atg1p signalling complex" EXACT [] +synonym: "autophagy-initiation complex" EXACT [GOC:autophagy, GOC:pad, GOC:PARL, PMID:26754330] +synonym: "ULK complex" EXACT [PMID:28816597] +synonym: "ULK1 complex" EXACT [PMID:26921696] +synonym: "ULK1 signaling complex" EXACT [] +synonym: "ULK1-ATG13-FIP200 complex" EXACT [] +synonym: "ULK1-ATG13-RB1CC1 complex" EXACT [] +xref: IntAct:EBI-2352849 +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bhm +creation_date: 2014-03-14T10:55:11Z + +[Term] +id: GO:1990317 +name: Gin4 complex +namespace: cellular_component +def: "A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved." [GOC:bhm, PMID:12058072] +synonym: "Gin4-septin complex" EXACT [] +xref: IntAct:EBI-2431392 +is_a: GO:1902554 ! serine/threonine protein kinase complex +relationship: part_of GO:0000144 ! cellular bud neck septin ring +created_by: bhm +creation_date: 2014-03-14T12:07:05Z + +[Term] +id: GO:1990318 +name: collagen type XIX trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529092 +is_a: GO:0005593 ! FACIT collagen trimer +is_a: GO:0098651 ! basement membrane collagen trimer +created_by: bhm +creation_date: 2014-03-14T16:05:57Z + +[Term] +id: GO:1990319 +name: collagen type XX trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XX) chains." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529132 +is_a: GO:0005593 ! FACIT collagen trimer +created_by: bhm +creation_date: 2014-03-14T16:31:21Z + +[Term] +id: GO:1990320 +name: collagen type XXI trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529143 +is_a: GO:0005593 ! FACIT collagen trimer +created_by: bhm +creation_date: 2014-03-14T16:40:14Z + +[Term] +id: GO:1990321 +name: collagen type XXII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529189 +is_a: GO:0005593 ! FACIT collagen trimer +created_by: bhm +creation_date: 2014-03-14T16:50:05Z + +[Term] +id: GO:1990322 +name: collagen type XXIII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529234 +is_a: GO:0030936 ! transmembrane collagen trimer +created_by: bhm +creation_date: 2014-03-14T22:01:00Z + +[Term] +id: GO:1990323 +name: collagen type XXIV trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529258 +is_a: GO:0005583 ! fibrillar collagen trimer +created_by: bhm +creation_date: 2014-03-14T22:05:53Z + +[Term] +id: GO:1990324 +name: collagen type XXVI trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXVI) chains." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529362 +is_a: GO:0005581 ! collagen trimer +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: bhm +creation_date: 2014-03-16T23:02:35Z + +[Term] +id: GO:1990325 +name: collagen type XXVII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone." [GOC:bhm, PMID:17876790, PMID:21421911] +xref: IntAct:EBI-2529377 +is_a: GO:0005583 ! fibrillar collagen trimer +created_by: bhm +creation_date: 2014-03-16T23:13:15Z + +[Term] +id: GO:1990326 +name: collagen type XXVIII trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXVIII) chains." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529426 +is_a: GO:0005581 ! collagen trimer +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: bhm +creation_date: 2014-03-16T23:15:28Z + +[Term] +id: GO:1990327 +name: collagen type XXV trimer +namespace: cellular_component +def: "A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane." [GOC:bhm, PMID:17876790] +xref: IntAct:EBI-2529312 +is_a: GO:0030936 ! transmembrane collagen trimer +created_by: bhm +creation_date: 2014-03-17T09:28:50Z + +[Term] +id: GO:1990328 +name: RPB4-RPB7 complex +namespace: cellular_component +def: "A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways." [GOC:bhm, PMID:15591044] +synonym: "RNA polymerase II, RPB4-RPB7 subcomplex" NARROW [] +xref: IntAct:EBI-2945755 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005622 ! intracellular +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/10931 xsd:anyURI +created_by: bhm +creation_date: 2014-03-17T09:37:07Z + +[Term] +id: GO:1990329 +name: IscS-TusA complex +namespace: cellular_component +def: "A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups." [GOC:bhm, PMID:20404999] +xref: IntAct:EBI-8869931 +is_a: GO:1990221 ! L-cysteine desulfurase complex +is_a: GO:1990228 ! sulfurtransferase complex +created_by: bhm +creation_date: 2014-03-17T10:00:47Z + +[Term] +id: GO:1990330 +name: IscS-IscU complex +namespace: cellular_component +def: "A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group." [GOC:bhm, PMID:20404999] +xref: IntAct:EBI-8870238 +is_a: GO:1990221 ! L-cysteine desulfurase complex +is_a: GO:1990228 ! sulfurtransferase complex +created_by: bhm +creation_date: 2014-03-17T10:08:19Z + +[Term] +id: GO:1990331 +name: Hpa2 acetyltransferase complex +namespace: cellular_component +def: "A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules." [GOC:bhm, PMID:10600387] +xref: IntAct:EBI-8871758 +is_a: GO:0070775 ! H3 histone acetyltransferase complex +is_a: GO:1902562 ! H4 histone acetyltransferase complex +created_by: bhm +creation_date: 2014-03-17T10:18:23Z + +[Term] +id: GO:1990332 +name: Ire1 complex +namespace: cellular_component +def: "A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript." [GOC:bf, GOC:bhm, PMID:18191223, PMID:25437541] +comment: An example of this is Ire1 in Escherichia coli (P32361) in PMID:18191223 (inferred from direct assay). +synonym: "ERN1 complex" RELATED [HGNC:3449] +synonym: "IRE1 dimer" EXACT [PMID:25437541] +xref: IntAct:EBI-8872439 +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1902554 ! serine/threonine protein kinase complex +is_a: GO:1902555 ! endoribonuclease complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: bhm +creation_date: 2014-03-17T10:46:58Z + +[Term] +id: GO:1990333 +name: mitotic checkpoint complex, CDC20-MAD2 subcomplex +namespace: cellular_component +def: "A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20." [GOC:bhm, PMID:15879521] +comment: An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay). +synonym: "CDC20-MAD2 complex" EXACT [] +xref: IntAct:EBI-1270646 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0033597 ! mitotic checkpoint complex +created_by: bhm +creation_date: 2014-03-17T14:11:35Z + +[Term] +id: GO:1990334 +name: Bfa1-Bub2 complex +namespace: cellular_component +def: "A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation." [GOC:bhm, PMID:16449187] +xref: IntAct:EBI-1271344 +is_a: GO:1902773 ! GTPase activator complex +relationship: part_of GO:0005816 ! spindle pole body +created_by: bhm +creation_date: 2014-03-17T14:34:21Z + +[Term] +id: GO:1990338 +name: laminin-14 complex +namespace: cellular_component +def: "A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains." [GOC:bhm, GOC:dph, PMID:15979864, PMID:17453709] +synonym: "laminin-423" EXACT [GOC:dph, GOC:sl, PMID:15979864] +xref: IntAct:EBI-2530020 +is_a: GO:0043256 ! laminin complex +created_by: bhm +creation_date: 2014-03-20T23:37:11Z + +[Term] +id: GO:1990339 +name: laminin-522 complex +namespace: cellular_component +def: "A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains." [GOC:bhm, GOC:dph, PMID:15979864, PMID:17453709] +synonym: "laminin-522" EXACT [] +xref: IntAct:EBI-2530034 +is_a: GO:0043256 ! laminin complex +created_by: bhm +creation_date: 2014-03-20T23:41:32Z + +[Term] +id: GO:1990340 +name: laminin-15 complex +namespace: cellular_component +def: "A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains." [GOC:bhm, PMID:17453709] +synonym: "laminin-523" EXACT [] +xref: IntAct:EBI-2530049 +is_a: GO:0043256 ! laminin complex +created_by: bhm +creation_date: 2014-03-20T23:48:25Z + +[Term] +id: GO:1990341 +name: thrombospondin complex +namespace: cellular_component +def: "A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour." [GOC:bhm, PMID:18193164] +xref: IntAct:EBI-2530370 +xref: IntAct:EBI-2530917 +xref: IntAct:EBI-2530961 +xref: IntAct:EBI-2530975 +xref: IntAct:EBI-2531058 +xref: IntAct:EBI-9251379 +xref: IntAct:EBI-9251408 +xref: IntAct:EBI-9251455 +xref: IntAct:EBI-9251502 +xref: IntAct:EBI-9251524 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0031012 ! extracellular matrix +created_by: bhm +creation_date: 2014-03-21T14:27:07Z + +[Term] +id: GO:1990342 +name: heterochromatin island +namespace: cellular_component +def: "A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi." [PMID:22144463, PMID:24210919] +comment: An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin islands are formed at meiotic genes during vegetative (mitotic) growth. +is_a: GO:0005720 ! nuclear heterochromatin +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/11247 xsd:anyURI +created_by: mah +creation_date: 2014-03-21T15:26:44Z + +[Term] +id: GO:1990343 +name: heterochromatin domain +namespace: cellular_component +def: "A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me)." [PMID:23151475, PMID:24210919] +comment: An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin domains preferentially assemble at sexual differentiation genes and retrotransposons. +synonym: "HOOD" EXACT [PMID:23151475] +is_a: GO:0005720 ! nuclear heterochromatin +created_by: mah +creation_date: 2014-03-21T15:40:48Z + +[Term] +id: GO:1990344 +name: secondary cell septum biogenesis +namespace: biological_process +def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division." [PMID:22891259] +is_a: GO:0044085 ! cellular component biogenesis +is_a: GO:1902410 ! mitotic cytokinetic process +relationship: part_of GO:0140278 ! mitotic division septum assembly +created_by: mah +creation_date: 2014-03-24T13:24:48Z + +[Term] +id: GO:1990346 +name: BID-BCL-xl complex +namespace: cellular_component +def: "A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators." [GOC:bhm, PMID:14634621] +xref: IntAct:EBI-709568 +xref: IntAct:EBI-822507 +xref: IntAct:EBI-822526 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-03-25T00:18:41Z + +[Term] +id: GO:1990347 +name: obsolete G*/A mismatch-specific adenine-DNA glycosylase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site." [PMID:24559510] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "G*/A mismatch-specific adenine-DNA glycosylase activity" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-03-25T10:14:37Z + +[Term] +id: GO:1990348 +name: obsolete G/A mismatch specific adenine DNA glycosylase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by me." [PMID:9737967] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "G/A mismatch specific adenine DNA glycosylase activity" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-03-25T10:55:45Z + +[Term] +id: GO:1990349 +name: gap junction-mediated intercellular transport +namespace: biological_process +def: "The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells." [GOC:hjd, PMID:14506308, PMID:23261543, Wikipedia:Gap_junction] +is_a: GO:0010496 ! intercellular transport +created_by: hjd +creation_date: 2014-03-25T18:05:44Z + +[Term] +id: GO:1990350 +name: glucose transporter complex +namespace: cellular_component +def: "A protein complex facilitating glucose transport into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] +comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay). +xref: IntAct:EBI-959455 +xref: IntAct:EBI-960644 +xref: IntAct:EBI-960674 +is_a: GO:1990351 ! transporter complex +created_by: bhm +creation_date: 2014-03-26T14:12:05Z + +[Term] +id: GO:1990351 +name: transporter complex +namespace: cellular_component +def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] +comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay). +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-03-26T14:23:27Z + +[Term] +id: GO:1990352 +name: BRE1 E3 ubiquitin ligase complex +namespace: cellular_component +def: "A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes." [GOC:bhm, PMID:19531475] +comment: An example of this is BRE1 in Saccharomyces cerevisiae (UniProt symbol Q07457) in PMID:19531475 (inferred from direct assay). +synonym: "BRE1 E3 ubiquitin-protein ligase complex" EXACT [] +synonym: "BRE1 oligomer" EXACT [] +xref: IntAct:EBI-9102292 +is_a: GO:0000151 ! ubiquitin ligase complex +created_by: bhm +creation_date: 2014-03-27T13:49:05Z + +[Term] +id: GO:1990353 +name: Fused-Smurf ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation." [GOC:bhm, PMID:21145463] +comment: An example of this is FUSED in Drosophila melanogaster (UniProt symbol P23647) in PMID:21145463 (inferred from direct assay). +xref: IntAct:EBI-3405462 +is_a: GO:0000151 ! ubiquitin ligase complex +created_by: bhm +creation_date: 2014-03-27T14:02:09Z + +[Term] +id: GO:1990354 +name: activated SUMO-E1 ligase complex +namespace: cellular_component +def: "A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins." [GOC:bhm, PMID:15660128] +comment: An example of this is SAE1 in human (UniProt symbol Q9UBE0) in PMID:15660128 (inferred from direct assay). +synonym: "SUMO-SAE1/2 complex" NARROW [] +xref: IntAct:EBI-9345927 +is_a: GO:0106068 ! SUMO ligase complex +relationship: has_part GO:0031510 ! SUMO activating enzyme complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-03-31T13:22:45Z + +[Term] +id: GO:1990355 +name: L-methionine salvage from methionine sulphoxide +namespace: biological_process +def: "The generation of L-methionine from methionine sulphoxide." [PMID:24118096] +synonym: "methionine salvage from methionine sulphoxide" BROAD [] +is_a: GO:0071267 ! L-methionine salvage +created_by: al +creation_date: 2014-04-02T12:55:01Z + +[Term] +id: GO:1990356 +name: sumoylated E2 ligase complex +namespace: cellular_component +def: "A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase." [GOC:bhm, PMID:18691969] +comment: An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay). +xref: IntAct:EBI-9347978 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-04-02T14:06:56Z + +[Term] +id: GO:1990357 +name: terminal web +namespace: cellular_component +def: "An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells." [GOC:kmv, PMID:19437512, PMID:24677443, PMID:7511618, Wikipedia:Terminal_web] +is_a: GO:0030864 ! cortical actin cytoskeleton +created_by: pr +creation_date: 2014-04-03T14:29:59Z + +[Term] +id: GO:1990358 +name: xylanosome +namespace: cellular_component +def: "A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose." [GOC:mengo_curators, PMID:16769147] +synonym: "xylanolytic complex" EXACT [] +is_a: GO:1902494 ! catalytic complex +created_by: tt +creation_date: 2014-04-05T18:08:54Z + +[Term] +id: GO:1990359 +name: stress response to zinc ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus." [GOC:kmv, pmid:17888400] +synonym: "response to zinc ion stress" EXACT [] +synonym: "response to zinc toxicity" RELATED [] +synonym: "stress response to zinc" BROAD [] +is_a: GO:0010043 ! response to zinc ion +is_a: GO:0097501 ! stress response to metal ion +created_by: kmv +creation_date: 2014-04-14T15:54:05Z + +[Term] +id: GO:1990360 +name: PKM2 protein kinase complex +namespace: cellular_component +def: "A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer." [GOC:bhm, PMID:24606918] +synonym: "PKM2-SAICAR complex" RELATED [] +synonym: "PKM2-SAICAR protein kinase complex" RELATED [] +is_a: GO:1902911 ! protein kinase complex +created_by: bhm +creation_date: 2014-04-17T14:03:36Z + +[Term] +id: GO:1990361 +name: PKM2 pyruvate kinase complex +namespace: cellular_component +def: "A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013)." [GOC:bhm, PMID:24606918] +comment: An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay). +synonym: "PKM2 homotetramer" EXACT [] +is_a: GO:1902912 ! pyruvate kinase complex +created_by: bhm +creation_date: 2014-04-17T14:16:24Z + +[Term] +id: GO:1990362 +name: butanol dehydrogenase activity +namespace: molecular_function +def: "Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+." [GOC:mengo_curators, PMID:1999395] +xref: RHEA:33200 +is_a: GO:0004022 ! alcohol dehydrogenase (NAD+) activity +created_by: tt +creation_date: 2014-04-23T21:14:09Z + +[Term] +id: GO:1990363 +name: obsolete response to hydrolysate +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis)." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to hydrolysate" EXACT [] +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:12:24Z + +[Term] +id: GO:1990364 +name: obsolete response to aldehyde +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to aldehyde" EXACT [] +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:18:04Z + +[Term] +id: GO:1990365 +name: obsolete response to phenol +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to phenol" EXACT [] +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:20:00Z + +[Term] +id: GO:1990366 +name: obsolete response to organic acid +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to organic acid" EXACT [] +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:21:26Z + +[Term] +id: GO:1990368 +name: obsolete process resulting in tolerance to hydrolysate +namespace: biological_process +def: "OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis)." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "process resulting in tolerance to hydrolysate" EXACT [] +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:27:51Z + +[Term] +id: GO:1990370 +name: obsolete process resulting in tolerance to aldehyde +namespace: biological_process +def: "OBSOLETE. A response that results in a state of tolerance to aldehyde." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted because it does not represent a clear process. +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:30:50Z + +[Term] +id: GO:1990371 +name: obsolete process resulting in tolerance to phenol +namespace: biological_process +def: "OBSOLETE. A response that results in a state of tolerance to phenol." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted because it does not represent a clear process. +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:32:48Z + +[Term] +id: GO:1990372 +name: obsolete process resulting in tolerance to organic acid +namespace: biological_process +def: "OBSOLETE. A response that results in a state of tolerance to organic acid." [GOC:mengo_curators, PMID:23356676] +comment: This term was obsoleted because it does not represent a clear process. +is_obsolete: true +created_by: tt +creation_date: 2014-04-23T22:34:12Z + +[Term] +id: GO:1990374 +name: Kir2 inward rectifier potassium channel complex +namespace: cellular_component +def: "A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells." [GOC:bhm, PMID:16834334] +comment: An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay). +synonym: "Kir2.1 complex" NARROW [] +xref: IntAct:EBI-9510554 +xref: IntAct:EBI-9511072 +is_a: GO:1902937 ! inward rectifier potassium channel complex +created_by: bhm +creation_date: 2014-04-25T15:29:15Z + +[Term] +id: GO:1990375 +name: baculum development +namespace: biological_process +def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296] +synonym: "os penis development" EXACT [GOC:sl] +synonym: "penile bone development" EXACT [GOC:sl] +synonym: "penis bone development" EXACT [GOC:sl] +is_a: GO:0048608 ! reproductive structure development +is_a: GO:0060348 ! bone development +created_by: sl +creation_date: 2014-05-01T23:59:13Z + +[Term] +id: GO:1990376 +name: obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition." [PMID:9135083] +comment: This term was made obsolete because it would not be used for annotation. +is_obsolete: true +created_by: al +creation_date: 2014-05-07T08:51:19Z + +[Term] +id: GO:1990377 +name: organomineral extracellular matrix +namespace: cellular_component +def: "An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight." [GOC:jh2, PMID:15994301] +comment: An example is found in shell calcitic prisms of the Mediterranean fan mussel Pinna nobilis (PMID:15994301), but the term may also be useful to annotate bone and eggshell proteins. +is_a: GO:0031012 ! extracellular matrix +property_value: RO:0002161 NCBITaxon:33090 +property_value: RO:0002161 NCBITaxon_Union:0000023 +created_by: pr +creation_date: 2014-05-07T10:02:28Z + +[Term] +id: GO:1990378 +name: upstream stimulatory factor complex +namespace: cellular_component +def: "A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters." [GOC:bhm, PMID:8576131] +comment: An example of this is USF1 in human (UniProt symbol P22415) in PMID:8576131 (inferred from direct assay). +synonym: "USF complex" EXACT [] +synonym: "USF1 homodimer" NARROW [] +synonym: "USF1-USF2 heterodimer" NARROW [] +synonym: "USF2 homodimer" NARROW [] +xref: IntAct:EBI-9518693 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-05-07T15:41:42Z + +[Term] +id: GO:1990379 +name: lipid transport across blood-brain barrier +namespace: biological_process +def: "The directed movement of lipid molecules passing through the blood-brain barrier." [GOC:sjp, PMID:24345162] +synonym: "lipid transport across blood brain barrier" EXACT [] +is_a: GO:0006869 ! lipid transport +is_a: GO:0150104 ! transport across blood-brain barrier +created_by: sjp +creation_date: 2014-05-08T09:52:28Z + +[Term] +id: GO:1990380 +name: Lys48-specific deubiquitinase activity +namespace: molecular_function +def: "Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein." [GOC:bf, GOC:PARL, PMID:22970133] +synonym: "K48-specific deubiquitinase activity" EXACT [PMID:22970133] +synonym: "K48-specific deubiquitinating activity" EXACT [PMID:22970133] +xref: Reactome:R-HSA-5690870 "OTUD7B,TNFAIP3 deubiquitinate TRAF6" +is_a: GO:0101005 ! ubiquitinyl hydrolase activity +relationship: part_of GO:0071108 ! protein K48-linked deubiquitination +created_by: bf +creation_date: 2014-05-15T14:31:07Z + +[Term] +id: GO:1990381 +name: ubiquitin-specific protease binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ubiquitin-specific protease." [GOC:bf, GOC:PARL, PMID:24063750] +synonym: "deubiquitinase binding" EXACT [GOC:bf] +synonym: "deubiquitinating enzyme binding" EXACT [PMID:24063750] +is_a: GO:0002020 ! protease binding +created_by: bf +creation_date: 2014-05-19T10:01:53Z + +[Term] +id: GO:1990382 +name: obsolete melanosome assembly +namespace: biological_process +def: "OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored." [GOC:bf, GOC:PARL, PMID:22511774] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "melanosome biogenesis" EXACT [PMID:22511774] +is_obsolete: true +created_by: bf +creation_date: 2014-05-20T16:06:04Z + +[Term] +id: GO:1990383 +name: cellular response to biotin starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin." [PMID:12557275] +is_a: GO:0009267 ! cellular response to starvation +created_by: al +creation_date: 2014-05-21T10:06:58Z + +[Term] +id: GO:1990384 +name: hyaloid vascular plexus regression +namespace: biological_process +def: "The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression." [GOC:hjd, PMID:18841878] +is_a: GO:0060033 ! anatomical structure regression +relationship: part_of GO:0043010 ! camera-type eye development +created_by: hjd +creation_date: 2014-05-28T18:43:21Z + +[Term] +id: GO:1990385 +name: meiotic spindle midzone +namespace: cellular_component +def: "The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap." [GOC:kmv\,PMID\:12707312] +is_a: GO:0051233 ! spindle midzone +relationship: part_of GO:0072687 ! meiotic spindle +created_by: kmv +creation_date: 2014-05-29T20:52:44Z + +[Term] +id: GO:1990386 +name: mitotic cleavage furrow ingression +namespace: biological_process +def: "Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed." [GOC:kmv, PMID:12707312] +is_a: GO:0036090 ! cleavage furrow ingression +is_a: GO:1902410 ! mitotic cytokinetic process +created_by: kmv +creation_date: 2014-05-29T20:58:27Z + +[Term] +id: GO:1990387 +name: isogloboside biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides)." [GOC:hjd, PMID:22875802] +xref: CHEBI:78257 +is_a: GO:0006688 ! glycosphingolipid biosynthetic process +created_by: hjd +creation_date: 2014-05-30T17:36:51Z + +[Term] +id: GO:1990388 +name: xylem-to-phloem iron transport +namespace: biological_process +def: "The directed movement of iron ions into the phloem from the xylem." [GOC:tb, PMID:24867923] +is_a: GO:0006826 ! iron ion transport +is_a: GO:0010233 ! phloem transport +created_by: tb +creation_date: 2014-05-30T21:06:50Z + +[Term] +id: GO:1990389 +name: CUE1-UBC7 ubiquitin-conjugating enzyme complex +namespace: cellular_component +def: "A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1." [GOC:bhm, PMID:23028185] +comment: An example of this is UBC7 in Saccharomyces cerevisiae (Q02159) in PMID:16179953 (inferred from direct assay). +synonym: "CUE1-UBC7 ubiquitin-conjugating enzyme (E2)" EXACT [] +xref: IntAct:EBI-9207004 +is_a: GO:0000835 ! ER ubiquitin ligase complex +is_a: GO:0031371 ! ubiquitin conjugating enzyme complex +created_by: bhm +creation_date: 2014-06-02T15:35:58Z + +[Term] +id: GO:1990390 +name: protein K33-linked ubiquitination +namespace: biological_process +def: "A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein." [PMID:24768539] +is_a: GO:0000209 ! protein polyubiquitination +created_by: sp +creation_date: 2014-06-03T12:22:05Z + +[Term] +id: GO:1990391 +name: DNA repair complex +namespace: cellular_component +def: "A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway." [GOC:bhm, PMID:17217467, PMID:20551348, PMID:22749910, PMID:24192350] +synonym: "DNA damage repair complex" EXACT [] +synonym: "WHY1 complex" NARROW [] +xref: IntAct:EBI-16426962 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2014-06-04T09:15:24Z + +[Term] +id: GO:1990392 +name: EFF-1 complex +namespace: cellular_component +def: "A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer." [GOC:bhm, PMID:24725407] +comment: An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay). +xref: IntAct:EBI-9526622 +is_a: GO:0098797 ! plasma membrane protein complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2014-06-04T14:45:02Z + +[Term] +id: GO:1990393 +name: 3M complex +namespace: cellular_component +def: "A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity." [PMID:24793695, PMID:24793696] +is_a: GO:0032991 ! protein-containing complex +created_by: sp +creation_date: 2014-06-05T06:40:49Z + +[Term] +id: GO:1990394 +name: cellular response to cell wall damage +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell." [PMID:17287531] +is_a: GO:0051716 ! cellular response to stimulus +relationship: has_part GO:0071433 ! cell wall repair +created_by: al +creation_date: 2014-06-05T16:45:33Z + +[Term] +id: GO:1990395 +name: meiotic spindle pole body organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body." [GOC:vw] +is_a: GO:0051300 ! spindle pole body organization +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0000212 ! meiotic spindle organization +created_by: tb +creation_date: 2014-06-06T01:41:05Z + +[Term] +id: GO:1990396 +name: single-strand break repair via homologous recombination +namespace: biological_process +def: "The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule." [GOC:bhm, PMID:24339919] +is_a: GO:0000012 ! single strand break repair +is_a: GO:0000725 ! recombinational repair +is_a: GO:0042275 ! error-free postreplication DNA repair +created_by: bhm +creation_date: 2014-06-09T10:47:04Z + +[Term] +id: GO:1990397 +name: queuosine salvage +namespace: biological_process +def: "Any process which produces queuosine from derivatives of it, without de novo synthesis." [GOC:vw, PMID:24911101] +is_a: GO:0008616 ! queuosine biosynthetic process +is_a: GO:0043174 ! nucleoside salvage +created_by: pr +creation_date: 2014-06-10T14:56:12Z + +[Term] +id: GO:1990398 +name: Cus cation efflux complex +namespace: cellular_component +def: "Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth." [GOC:bhm, PMID:23122209] +comment: An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209. +synonym: "copper efflux complex" NARROW [] +synonym: "copper efflux system" NARROW [] +synonym: "Cus cation efflux system" EXACT [] +synonym: "silver efflux complex" NARROW [] +synonym: "silver efflux system" NARROW [] +xref: IntAct:EBI-9010676 +is_a: GO:0098797 ! plasma membrane protein complex +is_a: GO:1903113 ! copper ion transmembrane transporter complex +is_a: GO:1903114 ! silver ion transmembrane transporter complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2014-06-11T08:51:48Z + +[Term] +id: GO:1990399 +name: epithelium regeneration +namespace: biological_process +def: "The regrowth of lost or destroyed epithelium." [GOC:sl, PMID:19845688] +synonym: "regeneration of epithelium" EXACT [] +is_a: GO:0042246 ! tissue regeneration +is_a: GO:0060429 ! epithelium development +created_by: sl +creation_date: 2014-06-12T17:14:42Z + +[Term] +id: GO:1990400 +name: mitochondrial ribosomal large subunit rRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the mitochondrial large ribosomal subunit RNA (LSU rRNA), a constituent of the mitochondrial large ribosomal subunit." [PMID:24206665] +comment: In S. cerevisiae, this is the mitochondrial 21S rRNA +synonym: "21S rRNA binding" NARROW [] +synonym: "mitochondrial LSU rRNA binding" EXACT [] +is_a: GO:0070180 ! large ribosomal subunit rRNA binding +created_by: mcc +creation_date: 2014-06-23T16:47:09Z + +[Term] +id: GO:1990401 +name: embryonic lung development +namespace: biological_process +def: "The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure." [PMID:24785085] +is_a: GO:0048568 ! embryonic organ development +created_by: sl +creation_date: 2014-06-23T19:56:13Z + +[Term] +id: GO:1990402 +name: embryonic liver development +namespace: biological_process +def: "The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure." [PMID:15918910] +is_a: GO:0048568 ! embryonic organ development +created_by: sl +creation_date: 2014-06-23T20:52:03Z + +[Term] +id: GO:1990403 +name: embryonic brain development +namespace: biological_process +def: "The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure." [PMID:15918910] +is_a: GO:0048568 ! embryonic organ development +created_by: sl +creation_date: 2014-06-23T20:57:13Z + +[Term] +id: GO:1990404 +name: protein ADP-ribosylase activity +namespace: molecular_function +def: "The transfer, from NAD, of ADP-ribose to a protein amino acid residue." [PMID:1899243, RESID:AA0040, RESID:AA0168, RESID:AA0169, RESID:AA0231, RESID:AA0237, RESID:AA0295, wikipedia:ADP-ribosylation] +synonym: "ribosylase activity" BROAD [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +is_a: GO:0140096 ! catalytic activity, acting on a protein +relationship: part_of GO:0006471 ! protein ADP-ribosylation +created_by: pg +creation_date: 2014-06-24T07:04:44Z + +[Term] +id: GO:1990405 +name: protein antigen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein antigen." [PMID:9360996] +is_a: GO:0003823 ! antigen binding +is_a: GO:0005515 ! protein binding +property_value: RO:0002161 NCBITaxon:4751 +created_by: pm +creation_date: 2014-06-30T13:19:55Z + +[Term] +id: GO:1990406 +name: CGRP receptor complex +namespace: cellular_component +def: "A transmembrane, G protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP)." [GOC:bhm, PMID:20826335] +comment: An example of this is CALCRL in human (Q16602) in PMID:20826335 (inferred from direct assay). +synonym: "calcitonin gene-related polypeptide receptor complex" EXACT [] +synonym: "Calcitonin-gene-related peptide receptor complex" EXACT [] +synonym: "CGRP-R complex" EXACT [] +xref: IntAct:EBI-9009008 +is_a: GO:1903439 ! calcitonin family receptor complex +created_by: bhm +creation_date: 2014-07-01T14:57:43Z + +[Term] +id: GO:1990407 +name: calcitonin gene-related peptide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with calcitonin gene-related peptide (CGRP)." [GOC:bhm, PMID:10882736] +comment: An example of this is CALCRL in human (Q16602) in PMID:10882736 (inferred from direct assay/mutant phenotype/etc.). +synonym: "calcitonin-gene-related peptide binding" EXACT [] +synonym: "calcitonin-gene-related polypeptide binding" EXACT [] +synonym: "CGRP polypeptide binding" EXACT [] +is_a: GO:0097644 ! calcitonin family binding +created_by: bhm +creation_date: 2014-07-02T14:22:06Z + +[Term] +id: GO:1990408 +name: calcitonin gene-related peptide receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers." [GOC:bhm, PMID:10882736] +comment: An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736. +synonym: "calcitonin-gene-related peptide receptor signaling pathway" EXACT [] +synonym: "calcitonin-gene-related polypeptide receptor signaling pathway" EXACT [] +synonym: "CGRP receptor signaling pathway" EXACT [] +is_a: GO:0097646 ! calcitonin family receptor signaling pathway +created_by: bhm +creation_date: 2014-07-02T14:32:37Z + +[Term] +id: GO:1990409 +name: adrenomedullin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with adrenomedullin (AM)." [GOC:bhm, PMID:10882736] +comment: An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736. +synonym: "AM binding" EXACT [] +is_a: GO:0097644 ! calcitonin family binding +created_by: bhm +creation_date: 2014-07-02T14:37:19Z + +[Term] +id: GO:1990410 +name: adrenomedullin receptor signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell." [GOC:bhm, PMID:10882736] +comment: An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736. +synonym: "AM receptor signaling pathway" EXACT [] +is_a: GO:0097646 ! calcitonin family receptor signaling pathway +created_by: bhm +creation_date: 2014-07-02T14:43:31Z + +[Term] +id: GO:1990411 +name: hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) +namespace: molecular_function +def: "Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium." [PMID:24828577] +xref: MetaCyc:RXN-14428 +xref: RHEA:42688 +is_a: GO:0016846 ! carbon-sulfur lyase activity +relationship: part_of GO:0052699 ! ergothioneine biosynthetic process +created_by: mah +creation_date: 2014-07-02T15:45:43Z + +[Term] +id: GO:1990412 +name: hercynylselenocysteine lyase activity (selenoneine-forming) +namespace: molecular_function +def: "Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium." [PMID:24828577] +xref: RHEA:42696 +is_a: GO:0016846 ! carbon-sulfur lyase activity +created_by: mah +creation_date: 2014-07-02T15:51:07Z + +[Term] +id: GO:1990413 +name: eyespot apparatus +namespace: cellular_component +def: "A small pigmented organelle used in single-celled organisms to detect light." [Wikipedia:Eyespot_apparatus] +synonym: "eyespot" RELATED [] +synonym: "stigma" RELATED [] +is_a: GO:0043229 ! intracellular organelle +created_by: cjm +creation_date: 2014-07-03T21:26:24Z + +[Term] +id: GO:1990414 +name: replication-born double-strand break repair via sister chromatid exchange +namespace: biological_process +def: "The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks." [PMID:12820977, PMID:16888651\,GOC\:rb] +synonym: "replication-born DSB repair by SCE" EXACT [] +is_a: GO:0000724 ! double-strand break repair via homologous recombination +created_by: rb +creation_date: 2014-07-10T21:20:34Z + +[Term] +id: GO:1990415 +name: Pex17p-Pex14p docking complex +namespace: cellular_component +def: "A protein complex involved in the peroxisomal import machinery. In S. cerevisiae, this complex contains the proteins Pex17p, Pex14p, Pex19, and Pex13p." [GOC:rb, PMID:12667447] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2014-07-10T21:43:31Z + +[Term] +id: GO:1990416 +name: cellular response to brain-derived neurotrophic factor stimulus +namespace: biological_process +def: "A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus." [PMID:21958434] +synonym: "cellular response to BDNF stimulus" EXACT [] +is_a: GO:1990090 ! cellular response to nerve growth factor stimulus +created_by: sl +creation_date: 2014-07-11T17:55:59Z + +[Term] +id: GO:1990417 +name: snoRNA release from pre-rRNA +namespace: biological_process +def: "The release of snoRNA from pre-rRNA." [GOC:rb, PMID:16908538] +comment: An example of this process is yeast HAS1 from PMID:16908538, inferred from mutant phenotype assay. +is_a: GO:0006364 ! rRNA processing +created_by: rb +creation_date: 2014-07-11T21:43:27Z + +[Term] +id: GO:1990418 +name: response to insulin-like growth factor stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus." [PMID:21932665] +is_a: GO:0009725 ! response to hormone +created_by: sl +creation_date: 2014-07-14T22:47:59Z + +[Term] +id: GO:1990419 +name: obsolete response to elemental metal +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus." [PMID:22688007] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to elemental metal" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2014-07-15T20:17:56Z + +[Term] +id: GO:1990420 +name: establishment of septation initiation network asymmetry +namespace: biological_process +def: "The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies." [PMID:22786806] +synonym: "establishment of SIN asymmetry" EXACT [PMID:22786806] +is_a: GO:0031028 ! septation initiation signaling +created_by: al +creation_date: 2014-07-16T13:51:36Z + +[Term] +id: GO:1990422 +name: glyoxalase (glycolic acid-forming) activity +namespace: molecular_function +def: "Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor." [GOC:bf, GOC:PARL, PMID:22523093] +is_a: GO:0016836 ! hydro-lyase activity +relationship: part_of GO:0046295 ! glycolate biosynthetic process +relationship: part_of GO:1903190 ! glyoxal catabolic process +created_by: bf +creation_date: 2014-07-21T09:00:21Z + +[Term] +id: GO:1990423 +name: RZZ complex +namespace: cellular_component +def: "A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints." [PMID:12686595, PMID:15922598, PMID:20462495] +comment: Example annotations for this term would be D. melanogaster mit(1)15 (Q9W4X9), rod and zwilch (Q9VA00). +synonym: "Rod-Zwilch-Zw10 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0000776 ! kinetochore +created_by: jl +creation_date: 2014-07-23T11:16:42Z + +[Term] +id: GO:1990424 +name: protein arginine kinase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate." [GOC:imk, PMID:22517742] +comment: This reaction occurs in bacterial species e.g. Bacillus subtilis. +is_a: GO:0004672 ! protein kinase activity +created_by: jl +creation_date: 2014-07-23T13:35:56Z + +[Term] +id: GO:1990425 +name: ryanodine receptor complex +namespace: cellular_component +def: "A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom." [GOC:ame, PMID:22822064] +comment: An example of this is RyR1 in rabbit (P11716) in PMID:2550460 (inferred from electron microscopy). +synonym: "RyR" RELATED [] +xref: IntAct:EBI-9632656 +is_a: GO:0005891 ! voltage-gated calcium channel complex +relationship: part_of GO:0033017 ! sarcoplasmic reticulum membrane +created_by: anm +creation_date: 2014-07-24T09:36:41Z + +[Term] +id: GO:1990426 +name: mitotic recombination-dependent replication fork processing +namespace: biological_process +def: "Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart." [GOC:mah, PMID:23093942] +synonym: "homologous recombination dependent replication fork recovery" RELATED [PMID:23093942] +synonym: "homologous recombination-dependent replication fork processing" EXACT [] +is_a: GO:0031297 ! replication fork processing +is_a: GO:1990505 ! mitotic DNA replication maintenance of fidelity +relationship: has_part GO:0006312 ! mitotic recombination +created_by: mah +creation_date: 2014-07-24T09:42:54Z + +[Term] +id: GO:1990427 +name: stereocilia tip-link density +namespace: cellular_component +def: "An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane." [PMID:19447093, PMID:21709241] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0002140 ! stereocilia tip link +relationship: part_of GO:0042995 ! cell projection +created_by: sl +creation_date: 2014-07-25T20:55:36Z + +[Term] +id: GO:1990428 +name: miRNA transport +namespace: biological_process +def: "The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore." [GO:jl, PMID:24356509] +synonym: "microRNA transport" EXACT [] +is_a: GO:0050658 ! RNA transport +created_by: jl +creation_date: 2014-07-29T14:03:46Z + +[Term] +id: GO:1990429 +name: peroxisomal importomer complex +namespace: cellular_component +def: "A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners." [PMID:20154681, PMID:22375831] +synonym: "peroxisomal import pore" EXACT [] +synonym: "peroxisomal protein import machinery" EXACT [] +synonym: "Pex14 complex" NARROW [] +is_a: GO:1990351 ! transporter complex +is_a: GO:1990415 ! Pex17p-Pex14p docking complex +created_by: jl +creation_date: 2014-07-29T14:45:28Z + +[Term] +id: GO:1990430 +name: extracellular matrix protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a protein that is part of an extracellular matrix." [PMID:22355679] +is_a: GO:0005515 ! protein binding +created_by: jl +creation_date: 2014-07-29T14:57:07Z + +[Term] +id: GO:1990431 +name: priRNA 3'-end processing +namespace: biological_process +def: "The process of forming the mature 3' end of a priRNA molecule." [PMID:24095277] +synonym: "primal small RNA 3'-end processing" EXACT [] +synonym: "priRNA 3' end processing" EXACT [] +is_a: GO:0043628 ! ncRNA 3'-end processing +created_by: jl +creation_date: 2014-07-29T15:34:19Z + +[Term] +id: GO:1990432 +name: siRNA 3'-end processing +namespace: biological_process +def: "The process of forming the mature 3' end of a siRNA molecule." [PMID:24095277] +synonym: "siRNA 3' end processing" EXACT [] +synonym: "small interfering RNA 3'-end processing" EXACT [] +is_a: GO:0043628 ! ncRNA 3'-end processing +created_by: jl +creation_date: 2014-07-29T15:38:38Z + +[Term] +id: GO:1990433 +name: CSL-Notch-Mastermind transcription factor complex +namespace: cellular_component +def: "A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes." [GOC:bhm, GOC:dos, PMID:16530045] +synonym: "CSL-NotchIC-MASTERMIND complex" EXACT [] +xref: IntAct:EBI-9636287 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-07-30T14:41:43Z + +[Term] +id: GO:1990434 +name: lower tip-link density +namespace: cellular_component +def: "An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises." [PMID:19447093] +synonym: "LTLD" EXACT [] +is_a: GO:1990427 ! stereocilia tip-link density +created_by: sl +creation_date: 2014-07-30T16:34:34Z + +[Term] +id: GO:1990435 +name: upper tip-link density +namespace: cellular_component +def: "An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends." [PMID:19447093] +synonym: "UTLD" EXACT [] +is_a: GO:1990427 ! stereocilia tip-link density +created_by: sl +creation_date: 2014-07-30T16:36:32Z + +[Term] +id: GO:1990436 +name: obsolete MAPK cascade involved in oxidative stress signaling pathway +namespace: biological_process +def: "OBSOLETE. A series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxidative stress MAPK cascade involve many of the same proteins, but the pathways are slightly different, therefore Im req this term." [PMID:10398679] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "MAPK cascade involved in oxidative stress signaling pathway" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-07-31T10:10:38Z + +[Term] +id: GO:1990437 +name: snRNA 2'-O-methylation +namespace: biological_process +def: "The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule." [PMID:11842100, PMID:9844635] +is_a: GO:0001510 ! RNA methylation +is_a: GO:0040031 ! snRNA modification +created_by: mah +creation_date: 2014-07-31T11:58:18Z + +[Term] +id: GO:1990438 +name: U6 2'-O-snRNA methylation +namespace: biological_process +def: "The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule." [PMID:11842100, PMID:9844635] +is_a: GO:1990437 ! snRNA 2'-O-methylation +created_by: mah +creation_date: 2014-07-31T12:04:21Z + +[Term] +id: GO:1990439 +name: MAP kinase serine/threonine phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate." [PMID:10398679] +is_a: GO:0004722 ! protein serine/threonine phosphatase activity +is_a: GO:0033549 ! MAP kinase phosphatase activity +created_by: al +creation_date: 2014-07-31T12:21:04Z + +[Term] +id: GO:1990440 +name: positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:21113145] +synonym: "activation of transcription from RNA polymerase II promoter in response to ER stress" EXACT [GOC:bf] +synonym: "ER stress-induced upregulation of transcription" BROAD [GOC:bf] +synonym: "stimulation of transcription from RNA polymerase II promoter in response to ER stress" EXACT [GOC:bf] +synonym: "up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "up-regulation of transcription induced by ER stress" BROAD [GOC:bf, PMID:21113145] +synonym: "upregulation of Pol II transcription induced by ER stress" EXACT [GOC:bf, PMID:21113145] +synonym: "upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" EXACT [GOC:bf] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0036003 ! positive regulation of transcription from RNA polymerase II promoter in response to stress +created_by: bf +creation_date: 2014-07-31T12:56:54Z + +[Term] +id: GO:1990441 +name: negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:21113145] +synonym: "down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "ER stress-induced negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:bf] +synonym: "inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" EXACT [GOC:bf] +synonym: "negative regulation of transcription from RNA polymerase II promoter in response to ER stress" EXACT [GOC:bf] +synonym: "reduction of transcription from RNA polymerase II promoter under ER stress" EXACT [PMID:21113145] +synonym: "repression of transcription from RNA polymerase II promoter under ER stress" EXACT [PMID:21113145] +synonym: "suppression of transcription from RNA polymerase II promoter under ER stress" EXACT [PMID:21113145] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0097201 ! negative regulation of transcription from RNA polymerase II promoter in response to stress +created_by: bf +creation_date: 2014-07-31T13:08:54Z + +[Term] +id: GO:1990442 +name: intrinsic apoptotic signaling pathway in response to nitrosative stress +namespace: biological_process +def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions." [GOC:bf, GOC:PARL, PMID:23985028] +synonym: "nitrosative stress-induced apoptosis" RELATED [PMID:23985028] +synonym: "nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT [GOC:bf] +is_a: GO:0071500 ! cellular response to nitrosative stress +is_a: GO:0097193 ! intrinsic apoptotic signaling pathway +created_by: bf +creation_date: 2014-07-31T14:28:16Z + +[Term] +id: GO:1990443 +name: peptidyl-threonine autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein." [PMID:7803855] +is_a: GO:0018107 ! peptidyl-threonine phosphorylation +is_a: GO:0046777 ! protein autophosphorylation +created_by: al +creation_date: 2014-08-02T15:08:41Z + +[Term] +id: GO:1990444 +name: F-box domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an F-box domain of a protein." [GOC:bf, GOC:PARL, InterPro:IPR001810, PMID:12628165] +is_a: GO:0019904 ! protein domain specific binding +created_by: bf +creation_date: 2014-08-05T13:45:14Z + +[Term] +id: GO:1990445 +name: obsolete Multiciliate cell differentiation +namespace: biological_process +def: "OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems." [PMID:22231168, PMID:24934224] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "Multiciliate cell differentiation" EXACT [] +is_obsolete: true +created_by: sp +creation_date: 2014-08-05T14:31:28Z + +[Term] +id: GO:1990446 +name: U1 snRNP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a U1 small nuclear ribonucleoprotein particle." [PMID:14713954] +is_a: GO:0070990 ! snRNP binding +created_by: mah +creation_date: 2014-08-06T09:29:44Z + +[Term] +id: GO:1990447 +name: U2 snRNP binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any part of a U2 small nuclear ribonucleoprotein particle." [PMID:14713954] +is_a: GO:0070990 ! snRNP binding +created_by: mah +creation_date: 2014-08-06T09:33:38Z + +[Term] +id: GO:1990448 +name: exon-exon junction complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay." [GOC:sart, PMID:24967911] +synonym: "EJC binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: sart +creation_date: 2014-08-06T10:02:46Z + +[Term] +id: GO:1990449 +name: obsolete amylin receptor +namespace: cellular_component +def: "OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, gastric emptying, gastric acid secretion, postprandial glucagon secretion and food intake and aids weight loss." [GOC:bhm, PMID:10871269] +comment: An example of this is CALCR in human (P30988) in PMID:10871269. +synonym: "AMY1 receptor" NARROW [] +synonym: "AMY2 receptor" NARROW [] +synonym: "AMY3 receptor" NARROW [] +synonym: "amylin receptor" EXACT [] +synonym: "CALCR-RAMP1 receptor" NARROW [] +synonym: "CALCR-RAMP2 receptor" NARROW [] +synonym: "CALCR-RAMP3 receptor" NARROW [] +xref: IntAct:EBI-9008682 +xref: IntAct:EBI-9685417 +xref: IntAct:EBI-9685439 +is_obsolete: true +created_by: bhm +creation_date: 2014-08-06T10:21:37Z + +[Term] +id: GO:1990450 +name: linear polyubiquitin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next." [GOC:bf, GOC:PARL, PMID:23453807] +synonym: "M1-linked ubiquitin chain binding" EXACT [PMID:23453807] +is_a: GO:0043130 ! ubiquitin binding +created_by: bf +creation_date: 2014-08-06T11:10:26Z + +[Term] +id: GO:1990451 +name: cellular stress response to acidic pH +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution." [GOC:BHF, GOC:go_curators, GOC:rl, PMID:10615049] +comment: An example of this is NOX1 in human (Q9Y5S8) in PMID:10615049. +synonym: "cellular stress response to acidity" BROAD [] +is_a: GO:0062197 ! cellular response to chemical stress +is_a: GO:0071468 ! cellular response to acidic pH +created_by: jl +creation_date: 2014-08-06T14:06:58Z + +[Term] +id: GO:1990452 +name: Parkin-FBXW7-Cul1 ubiquitin ligase complex +namespace: cellular_component +def: "A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein." [GOC:bf, GOC:PARL, PMID:12628165] +synonym: "Park2-FBXW7-Cul1 complex" EXACT [GOC:bf] +synonym: "Parkin-FBXW7-Cul1 protein complex" EXACT [GOC:bf] +synonym: "Parkin-HSel-10-Cullin-1 complex" NARROW [PMID:12628165] +synonym: "Parkin/Cul1/F-box protein complex" EXACT [GOC:bf] +synonym: "PRKN-FBXW7-Cul1 complex" EXACT [] +is_a: GO:0000151 ! ubiquitin ligase complex +created_by: bf +creation_date: 2014-08-07T14:25:49Z + +[Term] +id: GO:1990453 +name: nucleosome disassembly/reassembly complex +namespace: cellular_component +def: "A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex." [GOC:bhm, PMID:24843044] +comment: An example of this is EAF7 in Saccharomyces cerevisiae (P53911) in PMID:24843044 (inferred from direct assay). +synonym: "eaf5/7/3 complex" NARROW [] +xref: IntAct:EBI-9682603 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-08-08T15:18:30Z + +[Term] +id: GO:1990454 +name: L-type voltage-gated calcium channel complex +namespace: cellular_component +def: "A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation." [GOC:ame, PMID:12946355] +comment: Examples of this are CACNA1S, CACNA2D1, CACNB1, CACNG1 in rabbit (UniProt symbol P07293, P13806, P19517 and P19518) in PMID:12946355 (inferred from direct assay). +synonym: "cardiac muscle L-type voltage-gated calcium channel complex" NARROW [] +synonym: "skeletal muscle L-type voltage-gated calcium channel complex" NARROW [] +is_a: GO:0005891 ! voltage-gated calcium channel complex +relationship: part_of GO:0030315 ! T-tubule +created_by: anm +creation_date: 2014-08-12T17:22:10Z + +[Term] +id: GO:1990455 +name: PTEN phosphatase complex +namespace: cellular_component +def: "A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function." [GOC:bhm, PMID:24766807] +comment: An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay). +synonym: "phosphatase and tensin homolog" EXACT [] +synonym: "phosphatase and tensin homolog deleted on chromosome ten homodimer" EXACT [] +synonym: "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer" EXACT [] +xref: IntAct:EBI-9637198 +xref: IntAct:EBI-9637224 +is_a: GO:1904144 ! phosphatidylinositol phosphate phosphatase complex +created_by: bhm +creation_date: 2014-08-13T10:21:20Z + +[Term] +id: GO:1990456 +name: mitochondrion-endoplasmic reticulum membrane tethering +namespace: biological_process +def: "The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles." [PMID:19556461, PMID:27875684] +synonym: "mitochondrion-endoplasmic reticulum attachment" EXACT [] +synonym: "mitochondrion-endoplasmic reticulum tethering" EXACT [] +synonym: "mitochondrion-ER attachment" EXACT [] +synonym: "mitochondrion-ER membrane tethering" EXACT [] +synonym: "mitochondrion-ER tethering" EXACT [] +is_a: GO:0016043 ! cellular component organization +is_a: GO:0140056 ! organelle localization by membrane tethering +created_by: mcc +creation_date: 2014-08-14T13:32:30Z + +[Term] +id: GO:1990457 +name: pexophagosome +namespace: cellular_component +def: "A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy." [PMID:22536249] +is_a: GO:0045335 ! phagocytic vesicle +created_by: dhl +creation_date: 2014-08-15T18:51:53Z + +[Term] +id: GO:1990458 +name: lipooligosaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria." [GOC:hjd, PMID:8894399] +comment: ChEBI distinguishes an oligosaccharide from a polysaccharide as the latter being anything of length 10 or greater. +synonym: "endotoxin binding" RELATED [] +synonym: "LOS binding" RELATED [] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: hjd +creation_date: 2014-08-15T19:58:08Z + +[Term] +id: GO:1990459 +name: transferrin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the transferrin receptor." [GOC:pm, PMID:9819414] +is_a: GO:0005102 ! signaling receptor binding +created_by: tb +creation_date: 2014-08-18T20:14:24Z + +[Term] +id: GO:1990460 +name: leptin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the leptin receptor." [GOC:pm, PMID:22405007] +is_a: GO:0005102 ! signaling receptor binding +created_by: tb +creation_date: 2014-08-18T20:17:43Z + +[Term] +id: GO:1990461 +name: detoxification of iron ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion." [GOC:sart, PMID:23064556] +is_a: GO:0061687 ! detoxification of inorganic compound +relationship: part_of GO:0010039 ! response to iron ion +created_by: sart +creation_date: 2014-08-19T10:12:46Z + +[Term] +id: GO:1990462 +name: omegasome +namespace: cellular_component +def: "Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites." [GOC:autophagy, GOC:mf, PMID:18725538, PMID:24591649] +is_a: GO:0043231 ! intracellular membrane-bounded organelle +relationship: part_of GO:0012505 ! endomembrane system +created_by: pr +creation_date: 2014-08-19T12:26:40Z + +[Term] +id: GO:1990463 +name: lateral cortical node +namespace: cellular_component +def: "A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins." [GOC:mah, PMID:25009287] +synonym: "Skb1-containing cortical node" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0097575 ! lateral cell cortex +created_by: pr +creation_date: 2014-08-20T09:04:45Z + +[Term] +id: GO:1990464 +name: D-2-hydroxyacid dehydrogenase (quinone) activity +namespace: molecular_function +def: "Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol." [EC:1.1.5.10, GOC:am, PMID:3013300, PMID:4582730] +comment: (R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors. +synonym: "(R)-2-hydroxy acid dehydrogenase activity" RELATED [EC:1.1.5.10] +synonym: "(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity" RELATED [EC:1.1.5.10] +synonym: "(R)-2-hydroxyacid:quinone oxidoreductase activity" EXACT [EC:1.1.5.10] +synonym: "D-lactate dehydrogenase (quinone) activity" RELATED [GOC:am] +synonym: "D-lactate dehydrogenase activity" RELATED [EC:1.1.5.10] +synonym: "D-lactate:quinone oxidoreductase activity" RELATED [GOC:am] +is_a: GO:0016901 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor +created_by: pr +creation_date: 2014-08-22T10:13:42Z + +[Term] +id: GO:1990465 +name: aldehyde oxygenase (deformylating) activity +namespace: molecular_function +def: "Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+)." [GOC:mengo_curators, PMID:22947199, RHEA:21440] +xref: EC:4.1.99.5 +xref: RHEA:21440 +is_a: GO:0016830 ! carbon-carbon lyase activity +created_by: tt +creation_date: 2014-08-25T15:16:43Z + +[Term] +id: GO:1990466 +name: protein autosumoylation +namespace: biological_process +def: "The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein." [PMID:21518767, PMID:23443663] +synonym: "protein auto-sumoylation" EXACT [] +synonym: "protein self-sumoylation" EXACT [] +is_a: GO:0016925 ! protein sumoylation +created_by: se +creation_date: 2014-08-25T22:37:21Z + +[Term] +id: GO:1990467 +name: NuA3a histone acetyltransferase complex +namespace: cellular_component +def: "A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p." [GOC:rb, PMID:25104842] +is_a: GO:0033100 ! NuA3 histone acetyltransferase complex +created_by: rb +creation_date: 2014-08-25T23:07:45Z + +[Term] +id: GO:1990468 +name: NuA3b histone acetyltransferase complex +namespace: cellular_component +def: "A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p." [GOC:rb, PMID:25104842] +is_a: GO:0033100 ! NuA3 histone acetyltransferase complex +created_by: rb +creation_date: 2014-08-25T23:13:37Z + +[Term] +id: GO:1990469 +name: Rhino-Deadlock-Cutoff Complex +namespace: cellular_component +def: "Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation." [GOC:bhm, PMID:24906153] +comment: An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153. +synonym: "RDC complex" EXACT [] +synonym: "rhi-del-cuff complex" EXACT [] +xref: IntAct:EBI-9694217 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0043073 ! germ cell nucleus +created_by: bhm +creation_date: 2014-08-29T14:08:37Z + +[Term] +id: GO:1990470 +name: piRNA cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs)." [GOC:bhm, PMID:24906153] +comment: An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay). +is_a: GO:1990837 ! sequence-specific double-stranded DNA binding +created_by: bhm +creation_date: 2014-08-29T14:23:38Z + +[Term] +id: GO:1990471 +name: piRNA uni-strand cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa." [GOC:bhm, PMID:24906153] +is_a: GO:1990470 ! piRNA cluster binding +created_by: bhm +creation_date: 2014-08-29T14:37:35Z + +[Term] +id: GO:1990472 +name: piRNA dual-strand cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription." [GOC:bhm, PMID:24906153] +comment: An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay). +is_a: GO:1990470 ! piRNA cluster binding +created_by: bhm +creation_date: 2014-08-29T14:50:54Z + +[Term] +id: GO:1990473 +name: ciliary targeting signal binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane." [GOC:krc, PMID:18256283, PMID:19575670, PMID:20603001, PMID:20697559] +synonym: "CTS binding" EXACT [] +is_a: GO:0005048 ! signal sequence binding +created_by: pr +creation_date: 2014-09-02T08:22:03Z + +[Term] +id: GO:1990474 +name: synaptic vesicle, readily releasable pool +namespace: cellular_component +def: "A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton." [GOC:pad, PMID:22745285] +synonym: "readily releasable pool of synaptic vesicles" EXACT [] +synonym: "RRP" RELATED [] +is_a: GO:0008021 ! synaptic vesicle +relationship: part_of GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2014-09-02T09:02:41Z + +[Term] +id: GO:1990475 +name: synaptic vesicle, recycling pool +namespace: cellular_component +def: "A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state." [GOC:pad, PMID:22745285] +synonym: "recycling pool of synaptic vesicles" EXACT [] +is_a: GO:0008021 ! synaptic vesicle +relationship: part_of GO:0098794 ! postsynapse +created_by: pr +creation_date: 2014-09-02T09:08:22Z + +[Term] +id: GO:1990476 +name: synaptic vesicle, resting pool +namespace: cellular_component +def: "A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool." [GOC:pad, PMID:22745285] +synonym: "reserve pool of synaptic vesicles" EXACT [PMID:15611727] +synonym: "resting pool of synaptic vesicles" EXACT [] +is_a: GO:0008021 ! synaptic vesicle +relationship: part_of GO:0043195 ! terminal bouton +created_by: pr +creation_date: 2014-09-02T09:12:37Z + +[Term] +id: GO:1990477 +name: NURS complex +namespace: cellular_component +alt_id: GO:1990345 +def: "The nuclear RNA silencing (NURS) complex is a protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as MTREC." [PMID:24210919, PMID:24713849, PMID:32012158] +comment: An example of this is the complex formed by Red1 and Mtl1 in S. pombe (UniProt symbols Q9UTR8 and O13799 respectively) in PMID:24210919 (inferred from direct assay). +synonym: "Mtl1-Red1 core complex" EXACT [PMID:24210919] +synonym: "MTREC complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005634 ! nucleus +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19059 xsd:anyURI +created_by: mah +creation_date: 2014-03-24T13:30:52Z + +[Term] +id: GO:1990478 +name: response to ultrasound +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus." [PMID:20950932] +is_a: GO:0009612 ! response to mechanical stimulus +created_by: sl +creation_date: 2014-09-09T22:11:32Z + +[Term] +id: GO:1990479 +name: obsolete response to lipoic acid +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus." [PMID:23232760] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to 5-(1,2-dithiolan-3-yl)pentanoic acid" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2014-09-09T22:20:41Z + +[Term] +id: GO:1990480 +name: obsolete geranyl diphosphate synthase +namespace: molecular_function +def: "OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis." [GOC:mengo_curators, PMID:10557273] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +replaced_by: GO:0004161 +created_by: tt +creation_date: 2014-09-10T01:14:17Z + +[Term] +id: GO:1990481 +name: mRNA pseudouridine synthesis +namespace: biological_process +def: "The intramolecular conversion of uridine to pseudouridine in an mRNA molecule." [PMID:25192136] +synonym: "mRNA pseudouridylation" EXACT [] +is_a: GO:0001522 ! pseudouridine synthesis +is_a: GO:0016556 ! mRNA modification +created_by: mcc +creation_date: 2014-09-12T15:13:39Z + +[Term] +id: GO:1990482 +name: sphingolipid alpha-glucuronosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC." [GOC:tb, PMID:25122154] +synonym: "inositol phosphorylceramide glucuronosyltransferase activity" RELATED [] +is_a: GO:0008194 ! UDP-glycosyltransferase activity +created_by: tb +creation_date: 2014-09-12T22:10:09Z + +[Term] +id: GO:1990483 +name: Clr6 histone deacetylase complex I'' +namespace: cellular_component +def: "A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3." [PMID:25002536] +is_a: GO:0000118 ! histone deacetylase complex +relationship: part_of GO:0000790 ! nuclear chromatin +created_by: al +creation_date: 2014-09-16T10:40:51Z + +[Term] +id: GO:1990484 +name: aerobic lactate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen." [GOC:mengo_curators, PMID:8941775] +synonym: "aerobic lactic acid catabolic process" RELATED [] +is_a: GO:1903457 ! lactate catabolic process +created_by: tt +creation_date: 2014-09-20T05:42:51Z + +[Term] +id: GO:1990485 +name: anaerobic lactate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen." [GOC:mengo_curators, PMID:11133436] +synonym: "anaerobic lactic acid catabolic process" RELATED [] +is_a: GO:1903457 ! lactate catabolic process +created_by: tt +creation_date: 2014-09-20T16:48:06Z + +[Term] +id: GO:1990486 +name: anaerobic fatty acid catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes." [GOC:mengo_curators, PMID:17329794] +synonym: "anaerobic fatty acid degradation" EXACT [] +is_a: GO:0009062 ! fatty acid catabolic process +created_by: tt +creation_date: 2014-09-20T17:25:48Z + +[Term] +id: GO:1990487 +name: anaerobic lignin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units." [DOI:10.1039/C3EE40932E, GOC:mengo_curators] +synonym: "anaerobic lignin degradation" EXACT [] +is_a: GO:0046274 ! lignin catabolic process +created_by: tt +creation_date: 2014-09-20T17:35:09Z + +[Term] +id: GO:1990488 +name: anaerobic cellulose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen." [GOC:mengo_curators, PMID:8561466] +synonym: "anaerobic cellulose degradation" EXACT [] +is_a: GO:0030245 ! cellulose catabolic process +created_by: tt +creation_date: 2014-09-20T17:43:59Z + +[Term] +id: GO:1990489 +name: anaerobic pectin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen." [GOC:mengo_curators, PMID:23079077] +synonym: "anaerobic pectin degradation" EXACT [] +is_a: GO:0045490 ! pectin catabolic process +created_by: tt +creation_date: 2014-09-20T18:09:53Z + +[Term] +id: GO:1990490 +name: archaeal proton-transporting A-type ATPase complex +namespace: cellular_component +def: "A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea." [GOC:mengo_curators, PMID:15473999, PMID:24650628] +synonym: "A-type ATPase protein complex" BROAD [] +synonym: "archaeal A-type ATPase protein complex" BROAD [] +is_a: GO:0016469 ! proton-transporting two-sector ATPase complex +created_by: tt +creation_date: 2014-09-20T19:13:55Z + +[Term] +id: GO:1990491 +name: methane biosynthetic process from methanol and hydrogen +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen." [GOC:mengo_curators, PMID:16347126] +synonym: "methane biosynthesis from methanol and hydrogen" EXACT [] +synonym: "methanogenesis from methanol and hydrogen" EXACT [] +is_a: GO:0015945 ! methanol metabolic process +is_a: GO:0019387 ! methanogenesis, from methanol +is_a: GO:1902421 ! hydrogen metabolic process +created_by: tt +creation_date: 2014-09-21T01:08:40Z + +[Term] +id: GO:1990492 +name: mitotic cell cycle checkpoint inhibiting CAR assembly +namespace: biological_process +def: "A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase." [PMID:12186944] +synonym: "Mad2-dependent mitotic cell cycle checkpoint" RELATED [GOC:dph, GOC:vw] +synonym: "mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly" EXACT [] +is_a: GO:0007093 ! mitotic cell cycle checkpoint +is_a: GO:1903500 ! negative regulation of mitotic actomyosin contractile ring assembly +created_by: vw +creation_date: 2014-09-23T12:43:22Z + +[Term] +id: GO:1990493 +name: obsolete cyclin H-CDK7 complex +namespace: cellular_component +def: "OBSOLETE. A protein complex consisting of cyclin H and cyclin-dependent kinase 7 (CDK7). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner." [PMID:9857180] +comment: This term was made obsolete because it was added in error. +synonym: "cyclin H-CDK7 complex" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-09-24T10:08:44Z + +[Term] +id: GO:1990494 +name: obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly." [PMID:18256290] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of mitotic cytokinesis, actomyosin contractile ring assembly" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-09-25T09:04:55Z + +[Term] +id: GO:1990495 +name: obsolete actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly +namespace: biological_process +def: "OBSOLETE. An actin filament organization process that contributes to actomyosin contractile ring assembly during mitotic cytokinesis." [PMID:8834798] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-09-25T09:19:27Z + +[Term] +id: GO:1990496 +name: obsolete regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly +namespace: biological_process +def: "OBSOLETE. An actin filament organization process that contributes to regulation of actomyosin contractile ring assembly during mitotic cytokinesis." [PMID:24798735] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2014-09-25T09:21:57Z + +[Term] +id: GO:1990497 +name: regulation of cytoplasmic translation in response to stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:vw, PMID:16278445] +is_a: GO:0043555 ! regulation of translation in response to stress +is_a: GO:2000765 ! regulation of cytoplasmic translation +created_by: vw +creation_date: 2014-09-26T11:11:29Z + +[Term] +id: GO:1990498 +name: mitotic spindle microtubule +namespace: cellular_component +def: "Any microtubule that is part of a mitotic spindle; anchored at one spindle pole." [GOC:vw] +is_a: GO:0005876 ! spindle microtubule +relationship: part_of GO:0072686 ! mitotic spindle +created_by: vw +creation_date: 2014-09-26T13:34:40Z + +[Term] +id: GO:1990499 +name: raps-insc complex +namespace: cellular_component +def: "Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2)." [GOC:bhm, PMID:22171003] +comment: An example of this is Insc in drome (Q9W2R4) in PMID:22171003 (inferred from physical interaction). +synonym: "partner of inscuteable-inscuteable complex" EXACT [] +synonym: "Rapsynoid-Inscuteable complex" EXACT [] +xref: IntAct:EBI-9674411 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0045179 ! apical cortex +created_by: bhm +creation_date: 2014-09-30T09:22:18Z + +[Term] +id: GO:1990500 +name: eif4e-cup complex +namespace: cellular_component +def: "A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo." [GOC:bhm, PMID:14723848] +comment: An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction). +synonym: "eukaryotic translation initiation factor 4E-cup complex" EXACT [] +xref: IntAct:EBI-9674930 +is_a: GO:1903502 ! translation repressor complex +relationship: part_of GO:0000932 ! P-body +created_by: bhm +creation_date: 2014-09-30T12:31:49Z + +[Term] +id: GO:1990501 +name: exon-exon junction subcomplex mago-y14 +namespace: cellular_component +def: "Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA." [GOC:bhm, PMID:12730685] +comment: An example of this is Mago in drome (P49028) in PMID:12730685 (inferred from direct assay). +synonym: "exon junction subcomplex MAGOH-Y14" EXACT [GOC:bhm] +synonym: "mago-y14 complex" RELATED [] +synonym: "MGN-RBM8A complex" EXACT [] +xref: IntAct:EBI-9549962 +is_a: GO:0035145 ! exon-exon junction complex +is_a: GO:1903503 ! ATPase inhibitor complex +created_by: bhm +creation_date: 2014-09-30T14:05:28Z + +[Term] +id: GO:1990502 +name: dense core granule maturation +namespace: biological_process +def: "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." [GOC:kmv, PMID:22654674] +synonym: "dense core vesicle maturation" EXACT [] +is_a: GO:0061792 ! secretory granule maturation +created_by: kmv +creation_date: 2014-09-30T20:35:11Z + +[Term] +id: GO:1990503 +name: dendritic lamellar body +namespace: cellular_component +def: "A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions." [PMID:7869120] +synonym: "DLB" EXACT [] +is_a: GO:0042599 ! lamellar body +relationship: part_of GO:0030425 ! dendrite +created_by: sl +creation_date: 2014-09-30T20:47:28Z + +[Term] +id: GO:1990504 +name: dense core granule exocytosis +namespace: biological_process +def: "The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels." [GOC:kmv, PMID:17553987, PMID:24653208] +synonym: "dense core vesicle exocytosis" EXACT [] +is_a: GO:0017156 ! calcium-ion regulated exocytosis +created_by: kmv +creation_date: 2014-09-30T21:05:50Z + +[Term] +id: GO:1990505 +name: mitotic DNA replication maintenance of fidelity +namespace: biological_process +alt_id: GO:1990510 +def: "Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication." [PMID:19185548] +synonym: "maintenance of fidelity involved in mitotic cell cycle DNA replication" EXACT [] +synonym: "maintenance of fidelity involved in mitotic DNA replication" EXACT [] +synonym: "mitotic DNA replication maintenance of fidelity" EXACT [] +is_a: GO:1902298 ! cell cycle DNA replication maintenance of fidelity +is_a: GO:1903047 ! mitotic cell cycle process +intersection_of: GO:1902298 ! cell cycle DNA replication maintenance of fidelity +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: part_of GO:1902969 ! mitotic DNA replication +created_by: al +creation_date: 2014-10-01T14:09:05Z + +[Term] +id: GO:1990506 +name: mitotic DNA-dependent DNA replication +namespace: biological_process +def: "A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle." [PMID:16120966] +is_a: GO:1902969 ! mitotic DNA replication +created_by: al +creation_date: 2014-10-01T14:13:23Z + +[Term] +id: GO:1990507 +name: ATP-independent chaperone mediated protein folding +namespace: biological_process +def: "The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis." [GOC:rb, PMID:25242142] +is_a: GO:0061077 ! chaperone-mediated protein folding +created_by: rb +creation_date: 2014-10-01T23:55:05Z + +[Term] +id: GO:1990508 +name: CKM complex +namespace: cellular_component +def: "Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8." [GOC:bhm, PMID:12200444] +comment: An example of this is SSN2 in Saccharomyces cerevisiae (P38931) in PMID:12200444 (inferred from physical interaction). +synonym: "CDK8 kinase module" EXACT [] +synonym: "SRB8-SRB11 complex" EXACT [] +synonym: "SRB8/9/10/11 complex" EXACT [] +xref: IntAct:EBI-2640924 +is_a: GO:0019908 ! nuclear cyclin-dependent protein kinase holoenzyme complex +created_by: bhm +creation_date: 2014-10-02T10:05:58Z + +[Term] +id: GO:1990509 +name: PYM-mago-Y14 complex +namespace: cellular_component +def: "Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans." [GOC:bhm, PMID:14968132] +comment: An example of this is wibg in Drosophila melanogaster (P82804) in PMID:14968132 (inferred from physical interaction). +synonym: "PYM-mago-RNA-binding protein 8A complex" EXACT [] +synonym: "wibg-mago-tsu complex" EXACT [] +xref: IntAct:EBI-9634190 +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990501 ! exon-exon junction subcomplex mago-y14 +created_by: bhm +creation_date: 2014-10-03T12:52:01Z + +[Term] +id: GO:1990511 +name: piRNA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv, PMID:24696457] +synonym: "Piwi-associated RNA biosynthetic process" EXACT [] +is_a: GO:0034587 ! piRNA metabolic process +created_by: kmv +creation_date: 2014-10-07T13:47:32Z + +[Term] +id: GO:1990512 +name: Cry-Per complex +namespace: cellular_component +def: "Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms." [GOC:bhm, PMID:24855952] +comment: An example of this is Cry1 in mouse (P97784) in PMID:24855952 (inferred from physical interaction). +xref: IntAct:EBI-9693126 +xref: IntAct:EBI-9693260 +xref: IntAct:EBI-9694282 +xref: IntAct:EBI-9695878 +xref: IntAct:EBI-9695921 +xref: IntAct:EBI-9695942 +xref: IntAct:EBI-9696219 +xref: IntAct:EBI-9696270 +xref: IntAct:EBI-9696293 +xref: IntAct:EBI-9696310 +xref: IntAct:EBI-9696328 +xref: IntAct:EBI-9696345 +is_a: GO:0017053 ! transcription repressor complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-10-08T10:53:07Z + +[Term] +id: GO:1990513 +name: CLOCK-BMAL transcription complex +namespace: cellular_component +def: "Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms." [GOC:bhm, PMID:23229515] +comment: An example of this is CLOCK in human (O15516) in PMID:23229515 (inferred from physical interaction). +synonym: "CLOCK/BMAL complex" EXACT [] +xref: IntAct:EBI-9696362 +xref: IntAct:EBI-9696901 +xref: IntAct:EBI-9696921 +xref: IntAct:EBI-9696951 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-10-08T13:10:24Z + +[Term] +id: GO:1990514 +name: 5' transitive RNA interference +namespace: biological_process +def: "An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA." [GOC:pf, PMID:24369430] +is_a: GO:0036453 ! transitive RNA interference +created_by: jl +creation_date: 2014-10-09T15:29:31Z + +[Term] +id: GO:1990515 +name: 3' transitive RNA interference +namespace: biological_process +def: "An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA." [GOC:pf, PMID:24369430] +is_a: GO:0036453 ! transitive RNA interference +created_by: jl +creation_date: 2014-10-09T15:31:01Z + +[Term] +id: GO:1990516 +name: ribonucleotide excision repair +namespace: biological_process +def: "The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase." [PMID:12475934, PMID:22864116] +is_a: GO:0070716 ! mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication +created_by: al +creation_date: 2014-10-14T12:24:37Z + +[Term] +id: GO:1990517 +name: obsolete protein localization to photoreceptor outer segment +namespace: biological_process +def: "OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment, which is a portion of a modified sensory cilium." [GOC:krc, PMID:20212494] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: krc +creation_date: 2014-10-14T14:01:34Z + +[Term] +id: GO:1990518 +name: single-stranded 3'-5' DNA helicase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'." [PMID:25165823] +is_a: GO:0017116 ! single-stranded DNA helicase activity +is_a: GO:0043138 ! 3'-5' DNA helicase activity +created_by: al +creation_date: 2014-10-22T10:17:40Z + +[Term] +id: GO:1990519 +name: pyrimidine nucleotide import into mitochondrion +namespace: biological_process +def: "The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix." [PMID:16194150] +synonym: "mitochondrial pyrimidine nucleotide import" EXACT [] +is_a: GO:0006864 ! pyrimidine nucleotide transport +is_a: GO:0072531 ! pyrimidine-containing compound transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-10-22T10:20:23Z + +[Term] +id: GO:1990520 +name: separase-securin complex +namespace: cellular_component +def: "A protein complex that includes separase (a protease which cleaves cohesin as part of mitotic sister chromatid separation) and securin, a protease inhibitor. Mitotic sister chromatid separation is inhibited until securin is degraded by the Anaphase Promoting Complex." [GOC:dos, GOC:vw, PMID:8978688] +synonym: "Cut1-2 complex" EXACT [PMID:8978688] +is_a: GO:1905369 ! endopeptidase complex +created_by: vw +creation_date: 2014-10-23T10:34:52Z + +[Term] +id: GO:1990521 +name: m7G(5')pppN diphosphatase activator activity +namespace: molecular_function +def: "Binds to and increases the activity of m7G(5')pppN diphosphatase." [PMID:22323607] +is_a: GO:0008047 ! enzyme activator activity +relationship: positively_regulates GO:0050072 ! m7G(5')pppN diphosphatase activity +created_by: vw +creation_date: 2014-10-23T11:20:56Z + +[Term] +id: GO:1990522 +name: tail spike morphogenesis +namespace: biological_process +def: "The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death." [GOC:kmv, PMID:17329362, PMID:6684600] +xref: WBbt:0006979 +xref: WBbt:0008072 +is_a: GO:0009653 ! anatomical structure morphogenesis +created_by: jl +creation_date: 2014-10-23T15:20:15Z + +[Term] +id: GO:1990523 +name: bone regeneration +namespace: biological_process +def: "The regrowth of bone following its loss or destruction." [PMID:25257467] +is_a: GO:0042246 ! tissue regeneration +created_by: sl +creation_date: 2014-10-30T15:47:39Z + +[Term] +id: GO:1990524 +name: INA complex +namespace: cellular_component +def: "A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p." [GOC:rn, PMID:24942160] +synonym: "INAC" EXACT [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +relationship: part_of GO:0031304 ! intrinsic component of mitochondrial inner membrane +created_by: jl +creation_date: 2014-11-03T16:03:39Z + +[Term] +id: GO:1990525 +name: BIR domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain." [GOC:ha, InterPro:IPR001370] +comment: An example of this is the Drosophila reaper gene in PMID:21886178. +synonym: "Baculovirus Inhibitor of apoptosis protein Repeat domain binding" EXACT [] +is_a: GO:0019904 ! protein domain specific binding +created_by: jl +creation_date: 2014-11-04T12:36:56Z + +[Term] +id: GO:1990526 +name: Ste12p-Dig1p-Dig2p complex +namespace: cellular_component +def: "A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae." [GOC:rb, PMID:16782869] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2014-11-05T22:49:32Z + +[Term] +id: GO:1990527 +name: Tec1p-Ste12p-Dig1p complex +namespace: cellular_component +def: "A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae." [GOC:rb, PMID:16782869] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2014-11-05T22:55:17Z + +[Term] +id: GO:1990528 +name: Rvs161p-Rvs167p complex +namespace: cellular_component +def: "A protein complex that is involved in endocytosis in the yeast S. cerevisiae." [GOC:rb, PMID:20610658] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2014-11-05T23:11:32Z + +[Term] +id: GO:1990529 +name: glycosylphosphatidylinositol-mannosyltransferase I complex +namespace: cellular_component +def: "A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M." [GOC:dph, GOC:rb, PMID:15635094] +synonym: "GPI-MT-I complex" RELATED [] +is_a: GO:0031501 ! mannosyltransferase complex +relationship: part_of GO:0005783 ! endoplasmic reticulum +created_by: rb +creation_date: 2014-11-06T01:02:31Z + +[Term] +id: GO:1990530 +name: Cdc50p-Drs2p complex +namespace: cellular_component +def: "A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome." [GOC:rb, PMID:15090616, PMID:22234261] +is_a: GO:1990531 ! phospholipid-translocating ATPase complex +created_by: rb +creation_date: 2014-11-06T01:29:31Z + +[Term] +id: GO:1990531 +name: phospholipid-translocating ATPase complex +namespace: cellular_component +def: "A protein complex that functions as a phospholipid-translocating P-Type ATPase." [GOC:dph, GOC:rb, PMID:15090616] +synonym: "aminophospholipid translocase complex" EXACT [] +synonym: "APLT complex" EXACT [] +synonym: "CDC50-DRS2 complex" NARROW [] +synonym: "CRF1-DNF3 complex" NARROW [] +synonym: "Dnf1-Lem3 complex" NARROW [] +synonym: "Dnf2-Lem3 complex" NARROW [] +synonym: "DNF3-CRF1 complex" NARROW [] +synonym: "DRS2-CDC50 complex" NARROW [] +synonym: "Lem3-Dnf1 complex" NARROW [] +synonym: "Lem3p-Dnf1p complex" NARROW [] +synonym: "P4-ATPase complex" EXACT [] +synonym: "phospholipid flippase complex" EXACT [] +is_a: GO:1990351 ! transporter complex +created_by: rb +creation_date: 2014-11-06T22:33:25Z + +[Term] +id: GO:1990532 +name: stress response to nickel ion +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus." [GOC:kmv, PMID:25330323] +synonym: "response to nickel ion stress" EXACT [] +synonym: "response to nickel toxicity" EXACT [] +synonym: "stress response to nickel" EXACT [] +is_a: GO:0097501 ! stress response to metal ion +created_by: kmv +creation_date: 2014-11-07T18:35:31Z + +[Term] +id: GO:1990533 +name: Dom34-Hbs1 complex +namespace: cellular_component +def: "A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay." [GOC:mcc, PMID:20890290, PMID:21102444, PMID:21448132, PMID:22503425] +synonym: "Dom34:Hbs1 complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: mcc +creation_date: 2014-11-07T20:49:03Z + +[Term] +id: GO:1990534 +name: thermospermine oxidase activity +namespace: molecular_function +def: "Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine." [PMID:24906355] +is_a: GO:0016647 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor +created_by: tb +creation_date: 2014-11-13T00:41:59Z + +[Term] +id: GO:1990535 +name: neuron projection maintenance +namespace: biological_process +def: "The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:kmv, PMID:25359212] +synonym: "axon homeostasis" RELATED [] +synonym: "axon maintenance" RELATED [] +synonym: "neurite maintenance" NARROW [] +synonym: "neuron process maintenance" EXACT [] +synonym: "neuron protrusion maintenance" EXACT [] +synonym: "neuronal cell projection maintenance" EXACT [] +is_a: GO:0106027 ! neuron projection organization +created_by: kmv +creation_date: 2014-11-13T22:24:05Z + +[Term] +id: GO:1990536 +name: phosphoenolpyruvate transmembrane import into Golgi lumen +namespace: biological_process +def: "The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane." [PMID:25195688] +is_a: GO:0089722 ! phosphoenolpyruvate transmembrane transport +created_by: vw +creation_date: 2014-11-14T10:17:01Z + +[Term] +id: GO:1990537 +name: mitotic spindle polar microtubule +namespace: cellular_component +def: "Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone." [PMID:16079915] +is_a: GO:0005827 ! polar microtubule +is_a: GO:1990498 ! mitotic spindle microtubule +created_by: vw +creation_date: 2014-11-14T15:32:38Z + +[Term] +id: GO:1990538 +name: xylan O-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan." [PMID:25141999] +is_a: GO:0016413 ! O-acetyltransferase activity +created_by: tb +creation_date: 2014-11-18T20:02:51Z + +[Term] +id: GO:1990539 +name: fructose import across plasma membrane +namespace: biological_process +def: "The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol." [PMID:10735857] +is_a: GO:0032445 ! fructose import +is_a: GO:0140271 ! hexose import across plasma membrane +created_by: vw +creation_date: 2014-11-19T10:57:17Z + +[Term] +id: GO:1990540 +name: mitochondrial manganese ion transmembrane transport +namespace: biological_process +def: "The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:12890866] +is_a: GO:0071421 ! manganese ion transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:03:09Z + +[Term] +id: GO:1990542 +name: mitochondrial transmembrane transport +namespace: biological_process +def: "The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion." [PMID:20533899] +is_a: GO:0006839 ! mitochondrial transport +is_a: GO:0055085 ! transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:19:21Z + +[Term] +id: GO:1990543 +name: mitochondrial S-adenosyl-L-methionine transmembrane transport +namespace: biological_process +def: "The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:14609944] +is_a: GO:1901962 ! S-adenosyl-L-methionine transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:26:27Z + +[Term] +id: GO:1990544 +name: mitochondrial ATP transmembrane transport +namespace: biological_process +def: "The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:18485069] +is_a: GO:0006855 ! drug transmembrane transport +is_a: GO:0015867 ! ATP transport +is_a: GO:0072530 ! purine-containing compound transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +is_a: GO:1901679 ! nucleotide transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:43:33Z + +[Term] +id: GO:1990545 +name: mitochondrial thiamine pyrophosphate transmembrane transport +namespace: biological_process +def: "The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:12411483] +is_a: GO:0030974 ! thiamine pyrophosphate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:47:15Z + +[Term] +id: GO:1990546 +name: mitochondrial tricarboxylic acid transmembrane transport +namespace: biological_process +def: "The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion." [GOC:vw] +is_a: GO:0035674 ! tricarboxylic acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:00:14Z + +[Term] +id: GO:1990547 +name: mitochondrial phosphate ion transmembrane transport +namespace: biological_process +def: "The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:9099701] +is_a: GO:0035435 ! phosphate ion transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T11:50:19Z + +[Term] +id: GO:1990548 +name: mitochondrial FAD transmembrane transport +namespace: biological_process +def: "The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:14555654] +is_a: GO:0035350 ! FAD transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:04:35Z + +[Term] +id: GO:1990549 +name: mitochondrial NAD transmembrane transport +namespace: biological_process +def: "The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:16291748] +is_a: GO:0035352 ! NAD transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:09:51Z + +[Term] +id: GO:1990550 +name: mitochondrial alpha-ketoglutarate transmembrane transport +namespace: biological_process +alt_id: GO:1990552 +def: "The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:11013234, PMID:20371607] +synonym: "mitochondrial 2-oxoglutarate transmembrane transport" EXACT [] +is_a: GO:0015742 ! alpha-ketoglutarate transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:11:59Z + +[Term] +id: GO:1990551 +name: mitochondrial 2-oxoadipate transmembrane transport +namespace: biological_process +def: "The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:11013234] +is_a: GO:0006835 ! dicarboxylic acid transport +is_a: GO:1905039 ! carboxylic acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:25:48Z + +[Term] +id: GO:1990553 +name: mitochondrial 5'-adenylyl sulfate transmembrane transport +namespace: biological_process +def: "The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:24296033] +is_a: GO:1902558 ! 5'-adenylyl sulfate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:32:01Z + +[Term] +id: GO:1990554 +name: mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport +namespace: biological_process +def: "The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:24296033] +is_a: GO:1902559 ! 3'-phospho-5'-adenylyl sulfate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:39:22Z + +[Term] +id: GO:1990555 +name: mitochondrial oxaloacetate transmembrane transport +namespace: biological_process +def: "The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:10428783] +is_a: GO:1902356 ! oxaloacetate(2-) transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:45:37Z + +[Term] +id: GO:1990556 +name: mitochondrial isopropylmalate transmembrane transport +namespace: biological_process +def: "The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:10428783] +is_a: GO:1902357 ! 2-isopropylmalate(2-) transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:47:11Z + +[Term] +id: GO:1990557 +name: mitochondrial sulfate transmembrane transport +namespace: biological_process +def: "The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:10428783] +is_a: GO:1902358 ! sulfate transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:49:35Z + +[Term] +id: GO:1990558 +name: mitochondrial malonate(1-) transmembrane transport +namespace: biological_process +def: "The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:10428783] +is_a: GO:1901553 ! malonic acid transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:52:43Z + +[Term] +id: GO:1990559 +name: mitochondrial coenzyme A transmembrane transport +namespace: biological_process +def: "The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:11158296] +is_a: GO:0035349 ! coenzyme A transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: vw +creation_date: 2014-11-19T12:58:26Z + +[Term] +id: GO:1990560 +name: obsolete DNA methyltransferase binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a DNA methyltransferase." [PMID:22880885] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "DNA methyltransferase binding" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2014-11-19T16:30:28Z + +[Term] +id: GO:1990561 +name: obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion starvation +namespace: biological_process +def: "OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions." [GOC:al, PMID:10593913] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: al +creation_date: 2014-11-25T14:21:55Z + +[Term] +id: GO:1990562 +name: syndecan-syntenin-ALIX complex +namespace: cellular_component +def: "An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery." [GOC:bhm, PMID:22660413] +comment: An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction). +synonym: "exosome complex" BROAD [] +xref: IntAct:EBI-9985210 +xref: IntAct:EBI-9985797 +is_a: GO:1990563 ! extracellular exosome complex +created_by: bhm +creation_date: 2014-11-25T16:30:47Z + +[Term] +id: GO:1990563 +name: extracellular exosome complex +namespace: cellular_component +def: "A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome." [GOC:bhm, PMID:22660413] +comment: An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction). +synonym: "exosome complex" EXACT [] +synonym: "extracellular vesicular exosome complex" EXACT [GOC:vesicles] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0070062 ! extracellular exosome +created_by: bhm +creation_date: 2014-11-25T16:35:53Z + +[Term] +id: GO:1990564 +name: protein polyufmylation +namespace: biological_process +def: "Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain." [PMID:25219498] +is_a: GO:0071569 ! protein ufmylation +created_by: jl +creation_date: 2014-11-26T14:15:36Z + +[Term] +id: GO:1990565 +name: HSP90-CDC37 chaperone complex +namespace: cellular_component +def: "A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signalling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins." [GOC:bhm, GOC:pad, GOC:PARL, PMID:21855797, PMID:22939624] +comment: An example of this is HSP90AB1 in human (UniProt symbol P08238) in PMID:21855797 (inferred from direct assay). +xref: IntAct:EBI-9990131 +xref: IntAct:EBI-9990540 +is_a: GO:0101031 ! chaperone complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bhm +creation_date: 2014-11-26T14:22:51Z + +[Term] +id: GO:1990566 +name: I(KACh) inward rectifier potassium channel complex +namespace: cellular_component +def: "An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits." [GOC:ame, PMID:9765280] +comment: Examples of this are KCNJ3 and KCNJ5 in human (Uniprot symbols P48549 and P48544) in PMID:9765280 inferred from orthology sequence evidence. +synonym: "GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex" RELATED [] +synonym: "Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex" RELATED [] +synonym: "muscarinic potassium channel complex" RELATED [] +xref: IntAct:EBI-9975539 +is_a: GO:1902937 ! inward rectifier potassium channel complex +created_by: ame +creation_date: 2014-11-26T15:16:14Z + +[Term] +id: GO:1990567 +name: DPS complex +namespace: cellular_component +def: "A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22." [PMID:24945319] +is_a: GO:0008287 ! protein serine/threonine phosphatase complex +created_by: al +creation_date: 2014-11-27T09:56:18Z + +[Term] +id: GO:1990568 +name: obsolete MIS18 complex +namespace: cellular_component +def: "OBSOLETE. A centromere complex assembly protein that is required for the deposition of CENP-A on the centromere. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP) to reach the centromeres. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly." [GOC:bhm, PMID:25036634] +comment: An example of this is MIS18A in human (Q9NYP9) in PMID:25036634 (inferred from physical interaction). +synonym: "MIS18 complex" EXACT [] +xref: IntAct:EBI-9872194 +xref: IntAct:EBI-9873644 +is_obsolete: true +created_by: bhm +creation_date: 2014-11-27T10:52:20Z + +[Term] +id: GO:1990569 +name: UDP-N-acetylglucosamine transmembrane transport +namespace: biological_process +alt_id: GO:0015788 +def: "The process in which UDP-N-acetylglucosamine is transported across a membrane." [PMID:10788474] +synonym: "UDP-N-acetylglucosamine transport" RELATED [] +is_a: GO:0015711 ! organic anion transport +is_a: GO:0090481 ! pyrimidine nucleotide-sugar transmembrane transport +is_a: GO:0098656 ! anion transmembrane transport +created_by: vw +creation_date: 2014-11-27T11:56:35Z + +[Term] +id: GO:1990570 +name: GDP-mannose transmembrane transport +namespace: biological_process +alt_id: GO:0015784 +def: "The process in which GDP-mannose is transported across a membrane." [PMID:9395539] +synonym: "GDP-mannose transport" RELATED [] +is_a: GO:0090480 ! purine nucleotide-sugar transmembrane transport +created_by: vw +creation_date: 2014-11-27T12:05:09Z + +[Term] +id: GO:1990571 +name: meiotic centromere clustering +namespace: biological_process +def: "The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I." [PMID:10366596, PMID:9009280] +synonym: "centromere clustering during meiosis" EXACT [] +synonym: "homologous chromosome movement towards spindle pole in meiosis I prometaphase" EXACT [] +is_a: GO:0016344 ! meiotic chromosome movement towards spindle pole +is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle +is_a: GO:0072594 ! establishment of protein localization to organelle +is_a: GO:0072698 ! protein localization to microtubule cytoskeleton +is_a: GO:0098653 ! centromere clustering +created_by: mah +creation_date: 2014-12-02T11:25:37Z + +[Term] +id: GO:1990572 +name: TERT-RMRP complex +namespace: cellular_component +def: "A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP)." [GOC:bf, GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:19701182] +synonym: "telomerase reverse transcriptase:RMRP RNA complex" EXACT [PMID:19701182] +is_a: GO:0031379 ! RNA-directed RNA polymerase complex +is_a: GO:1990904 ! ribonucleoprotein complex +created_by: bf +creation_date: 2014-12-02T11:29:12Z + +[Term] +id: GO:1990573 +name: potassium ion import across plasma membrane +namespace: biological_process +alt_id: GO:0010107 +def: "The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol." [PMID:9139127] +synonym: "potassium import" BROAD [] +synonym: "potassium ion import" BROAD [] +synonym: "potassium ion uptake" BROAD [GOC:dph, GOC:tb] +is_a: GO:0071805 ! potassium ion transmembrane transport +is_a: GO:0098659 ! inorganic cation import across plasma membrane +created_by: vw +creation_date: 2014-12-04T09:48:12Z + +[Term] +id: GO:1990574 +name: meiotic spindle astral microtubule +namespace: cellular_component +def: "Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [PMID:10366596] +is_a: GO:0000235 ! astral microtubule +intersection_of: GO:0000235 ! astral microtubule +intersection_of: part_of GO:0072687 ! meiotic spindle +relationship: part_of GO:0072687 ! meiotic spindle +created_by: vw +creation_date: 2014-12-04T09:55:09Z + +[Term] +id: GO:1990575 +name: mitochondrial L-ornithine transmembrane transport +namespace: biological_process +alt_id: GO:0000066 +def: "The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion." [PMID:9237680] +synonym: "mitochondrial ornithine transmembrane transport" BROAD [] +synonym: "mitochondrial ornithine transport" RELATED [] +is_a: GO:1903352 ! L-ornithine transmembrane transport +is_a: GO:1990542 ! mitochondrial transmembrane transport +created_by: mah +creation_date: 2014-12-05T11:29:49Z + +[Term] +id: GO:1990576 +name: G protein-coupled glucose receptor activity +namespace: molecular_function +def: "Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [PMID:15667320] +synonym: "G-protein coupled glucose receptor activity" EXACT [] +is_a: GO:0004930 ! G protein-coupled receptor activity +created_by: al +creation_date: 2014-12-08T03:15:12Z + +[Term] +id: GO:1990577 +name: C-terminal protein demethylation +namespace: biological_process +def: "The removal of a methyl group from the C-terminal amino acid of a protein." [PMID:11060018] +is_a: GO:0006482 ! protein demethylation +created_by: mcc +creation_date: 2014-12-08T20:55:17Z + +[Term] +id: GO:1990578 +name: perinuclear endoplasmic reticulum membrane +namespace: cellular_component +def: "The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus." [PMID:25454947] +synonym: "perinuclear ER membrane" EXACT [] +is_a: GO:0016020 ! membrane +intersection_of: GO:0016020 ! membrane +intersection_of: part_of GO:0097038 ! perinuclear endoplasmic reticulum +relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network +relationship: part_of GO:0097038 ! perinuclear endoplasmic reticulum +created_by: mcc +creation_date: 2014-12-09T01:13:01Z + +[Term] +id: GO:1990579 +name: peptidyl-serine trans-autophosphorylation +namespace: biological_process +def: "The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer." [GOC:bf, GOC:PARL, PMID:21317875] +synonym: "serine autophosphorylation in trans" EXACT [PMID:21317875] +synonym: "serine transautophosphorylation" EXACT [PMID:21317875] +is_a: GO:0036289 ! peptidyl-serine autophosphorylation +is_a: GO:0036290 ! protein trans-autophosphorylation +created_by: bf +creation_date: 2014-12-09T09:20:08Z + +[Term] +id: GO:1990580 +name: regulation of cytoplasmic translational termination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination." [PMID:11570975] +is_a: GO:0006449 ! regulation of translational termination +is_a: GO:2000765 ! regulation of cytoplasmic translation +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: regulates GO:0002184 ! cytoplasmic translational termination +relationship: regulates GO:0002184 ! cytoplasmic translational termination +created_by: vw +creation_date: 2014-12-10T15:48:55Z + +[Term] +id: GO:1990581 +name: obsolete lysosome lysis +namespace: biological_process +def: "OBSOLETE. The rupture of the lysosomal membrane and loss of contents as a result of osmotic change, G-protein-driven disintegration, or unspecified cause." [PMID:24472, PMID:9538255] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "lysosomal lysis" EXACT [] +synonym: "lysosome lysis" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2014-12-10T18:54:00Z + +[Term] +id: GO:1990582 +name: obsolete intracellular membrane-bounded organelle binding +namespace: molecular_function +def: "OBSOLETE. The temporary binding of a protein or protein complex to the membrane of an intracellular membrane-bounded organelle." [PMID:16100119, PMID:9538255] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "intracellular membrane-bounded organelle binding" EXACT [] +synonym: "intracellular membrane-enclosed organelle binding" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2014-12-10T19:37:09Z + +[Term] +id: GO:1990583 +name: phospholipase D activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme phospholipase D." [PMID:7972129] +is_a: GO:0016004 ! phospholipase activator activity +relationship: positively_regulates GO:0004630 ! phospholipase D activity +created_by: sl +creation_date: 2014-12-10T21:04:46Z + +[Term] +id: GO:1990584 +name: cardiac Troponin complex +namespace: cellular_component +def: "A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction." [GOC:ame, PMID:12840750] +synonym: "cTnC:cTnI:cTnT" RELATED [] +xref: IntAct:EBI-9980814 +is_a: GO:0005861 ! troponin complex +created_by: ame +creation_date: 2014-12-12T16:51:41Z + +[Term] +id: GO:1990585 +name: hydroxyproline O-arabinosyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+." [EC:2.4.2.-, PMID:24036508] +synonym: "HPAT" EXACT [] +is_a: GO:0016763 ! transferase activity, transferring pentosyl groups +created_by: tb +creation_date: 2014-12-12T18:22:20Z + +[Term] +id: GO:1990586 +name: divisome complex +namespace: cellular_component +def: "A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells." [GOC:bhm, PMID:15165235, PMID:21784946] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030428 ! cell septum +created_by: bhm +creation_date: 2014-12-15T09:13:38Z + +[Term] +id: GO:1990587 +name: FtsQBL complex +namespace: cellular_component +def: "A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ." [GOC:bhm, PMID:15165235, PMID:21784946] +comment: An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction). +synonym: "FtsB-FtsL-FtsQ complex" EXACT [] +xref: IntAct:EBI-9547109 +is_a: GO:1990586 ! divisome complex +created_by: bhm +creation_date: 2014-12-15T09:25:09Z + +[Term] +id: GO:1990588 +name: FtsBL complex +namespace: cellular_component +def: "A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL." [GOC:bhm, PMID:15165235, PMID:21784946] +comment: An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction). +synonym: "FtsB-FtsL complex" EXACT [] +xref: IntAct:EBI-9997581 +is_a: GO:1990586 ! divisome complex +relationship: part_of GO:0005829 ! cytosol +relationship: part_of GO:1990587 ! FtsQBL complex +created_by: bhm +creation_date: 2014-12-15T09:33:00Z + +[Term] +id: GO:1990589 +name: ATF4-CREB1 transcription factor complex +namespace: cellular_component +def: "Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway." [GOC:bhm, PMID:12871976] +xref: IntAct:EBI-10043081 +xref: IntAct:EBI-10043332 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-12-15T14:22:44Z + +[Term] +id: GO:1990590 +name: ATF1-ATF4 transcription factor complex +namespace: cellular_component +def: "Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway." [GOC:bhm, PMID:12871976] +comment: An example of this is ATF1in human (P18846) in PMID:12871976 (inferred from physical interaction). +xref: IntAct:EBI-10043123 +xref: IntAct:EBI-10043370 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005634 ! nucleus +created_by: bhm +creation_date: 2014-12-15T14:25:56Z + +[Term] +id: GO:1990591 +name: asparagine transmembrane import into vacuole +namespace: biological_process +def: "The directed movement of asparagine into the vacuole across the vacuolar membrane." [PMID:20388511] +is_a: GO:0034491 ! neutral amino acid transmembrane import into vacuole +is_a: GO:1903713 ! asparagine transmembrane transport +created_by: vw +creation_date: 2014-12-15T16:33:46Z + +[Term] +id: GO:1990592 +name: protein K69-linked ufmylation +namespace: biological_process +def: "A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein." [PMID:25219498] +is_a: GO:1990564 ! protein polyufmylation +created_by: jl +creation_date: 2014-12-15T17:01:23Z + +[Term] +id: GO:1990593 +name: nascent polypeptide-associated complex binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the nascent polypeptide-associated complex, which is a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome." [PMID:25487825] +synonym: "NAC binding" EXACT [] +synonym: "NACA binding" EXACT [] +is_a: GO:0044877 ! protein-containing complex binding +created_by: mcc +creation_date: 2014-12-15T22:20:45Z + +[Term] +id: GO:1990594 +name: L-altrarate dehydratase activity +namespace: molecular_function +def: "Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O." [PMID:17649980] +synonym: "L-talarate dehydratase activity" EXACT [] +xref: RHEA:44028 +is_a: GO:0016836 ! hydro-lyase activity +created_by: jl +creation_date: 2014-12-16T14:23:55Z + +[Term] +id: GO:1990595 +name: mast cell secretagogue receptor activity +namespace: molecular_function +def: "Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells." [GOC:sp, PMID:25517090] +is_a: GO:0004930 ! G protein-coupled receptor activity +created_by: sp +creation_date: 2014-12-22T10:04:43Z + +[Term] +id: GO:1990596 +name: histone H3-K4 deacetylation +namespace: biological_process +def: "The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone." [PMID:20299449] +is_a: GO:0070932 ! histone H3 deacetylation +created_by: al +creation_date: 2014-12-23T19:37:15Z + +[Term] +id: GO:1990597 +name: AIP1-IRE1 complex +namespace: cellular_component +def: "A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein)." [GOC:bf, GOC:PARL, PMID:18281285] +synonym: "AIP1-ERN1 complex" RELATED [HGNC:3449] +synonym: "IRE1-DAB2IP complex" EXACT [GOC:bf] +synonym: "IRE1alpha-AIP1 complex" NARROW [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-01-05T15:14:35Z + +[Term] +id: GO:1990598 +name: repair of mitotic mono-orientation defect +namespace: biological_process +def: "The mitotic cell cycle process where mono-orientation defects are corrected in order to ensure sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles. Mono-orientation defects occur when both sister kinetochores are attached to MTs from one spindle pole in mitosis and meiosis II." [GOC:mtg_cell_cycle, GOC:vw, PMID:15525536] +synonym: "correction of mono-orientation defects" EXACT [] +synonym: "correction of syntelic kinetochore attachment, mitotic" EXACT [GOC:vw] +synonym: "repair of mitotic mono-orientation defects" EXACT [] +is_a: GO:0072479 ! response to mitotic cell cycle spindle assembly checkpoint signaling +is_a: GO:0140273 ! repair of mitotic kinetochore microtubule attachment defect +created_by: jl +creation_date: 2015-01-05T16:54:39Z + +[Term] +id: GO:1990599 +name: 3' overhang single-stranded DNA endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks." [PMID:25203555] +is_a: GO:0000014 ! single-stranded DNA endodeoxyribonuclease activity +created_by: al +creation_date: 2015-01-06T15:21:28Z + +[Term] +id: GO:1990600 +name: single-stranded DNA endodeoxyribonuclease activator activity +namespace: molecular_function +def: "Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity." [PMID:25203555] +is_a: GO:0008047 ! enzyme activator activity +relationship: part_of GO:0032079 ! positive regulation of endodeoxyribonuclease activity +created_by: al +creation_date: 2015-01-06T15:35:36Z + +[Term] +id: GO:1990601 +name: 5' overhang single-stranded DNA endodeoxyribonuclease activity +namespace: molecular_function +def: "Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks." [PMID:25203555] +is_a: GO:0000014 ! single-stranded DNA endodeoxyribonuclease activity +created_by: al +creation_date: 2015-01-06T16:24:39Z + +[Term] +id: GO:1990602 +name: obsolete importin alpha-subunit nuclear import complex +namespace: cellular_component +def: "OBSOLETE. A trimeric protein complex which functions to transport the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14)." [GOC:bhm, PMID:20122403] +comment: The reason for obsoletion is that these terms include the substrate of the reaction. +synonym: "Cdm-Mago-Tsu complex" NARROW [] +synonym: "Importin13-Mago-Tsu complex" NARROW [] +xref: IntAct:EBI-9673795 +is_obsolete: true +created_by: bhm +creation_date: 2015-01-09T16:28:54Z + +[Term] +id: GO:1990603 +name: dark adaptation +namespace: biological_process +def: "The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light." [GOC:hjd, http://www.ncbi.nlm.nih.gov/books/NBK11525/, ISBN:0198506732] +comment: The proteins RGS9-1 and Gb5L localize to the rod inner segment during dark adaptation, but to the rod outer segment during light adaptation. PMID:23555598 +is_a: GO:0071485 ! cellular response to absence of light +created_by: hjd +creation_date: 2015-01-09T20:35:46Z + +[Term] +id: GO:1990604 +name: IRE1-TRAF2-ASK1 complex +namespace: cellular_component +def: "A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K)." [GOC:bf, GOC:PARL, PMID:12050113, PMID:23000344] +synonym: "ERN1-TRAF2-ASK1 complex" RELATED [HGNC:3449] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005789 ! endoplasmic reticulum membrane +created_by: bf +creation_date: 2015-01-13T15:03:04Z + +[Term] +id: GO:1990605 +name: GU repeat RNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an RNA molecule containing GU repeats." [PMID:20081200] +is_a: GO:0003723 ! RNA binding +created_by: al +creation_date: 2015-01-13T18:18:01Z + +[Term] +id: GO:1990606 +name: membrane scission GTPase motor activity +namespace: molecular_function +def: "Catalysis of the generation of a 'twisting' activity resulting in the scission of a membrane, coupled to the hydrolysis of a nucleoside triphosphate." [PMID:11242086, PMID:23530241, PMID:24515348] +is_a: GO:0061791 ! GTPase motor activity +created_by: vw +creation_date: 2015-01-19T14:26:50Z + +[Term] +id: GO:1990607 +name: obsolete detection of stimulus involved in cytokinesis after mitosis checkpoint +namespace: biological_process +def: "OBSOLETE. The series of events in which information about whether cytokinesis has correctly completed, is received and converted into a molecular signal, contributing to a cytokinesis after mitosis checkpoint." [GOC:mtg_cell_cycle, GOC:vw, PMID:1234] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: jl +creation_date: 2015-01-19T14:43:34Z + +[Term] +id: GO:1990608 +name: mitotic spindle pole body localization +namespace: biological_process +alt_id: GO:0070632 +alt_id: GO:0071789 +def: "A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location." [PMID:24963130] +synonym: "establishment of spindle pole body localisation" NARROW [GOC:mah] +synonym: "establishment of spindle pole body localization" NARROW [] +synonym: "mitotic spindle pole body localization to nuclear envelope" NARROW [] +synonym: "spindle pole body docking" NARROW [GOC:vw] +synonym: "spindle pole body localisation in nuclear envelope" NARROW [GOC:mah] +synonym: "spindle pole body localization in nuclear envelope" NARROW [] +synonym: "spindle pole body localization to nuclear envelope" NARROW [] +synonym: "spindle pole body positioning" NARROW [GOC:vw] +is_a: GO:0070631 ! spindle pole body localization +is_a: GO:1903047 ! mitotic cell cycle process +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19149 xsd:anyURI +created_by: vw +creation_date: 2009-05-06T02:35:32Z + +[Term] +id: GO:1990609 +name: glutamate-cysteine ligase regulator activity +namespace: molecular_function +def: "Binds to and modulates the activity of glutamate-cysteine ligase." [PMID:8103521] +is_a: GO:0030234 ! enzyme regulator activity +created_by: vw +creation_date: 2015-01-20T12:51:13Z + +[Term] +id: GO:1990610 +name: acetolactate synthase regulator activity +namespace: molecular_function +def: "Binds to and modulates the activity of acetolactate synthase." [PMID:8972574] +is_a: GO:0030234 ! enzyme regulator activity +created_by: vw +creation_date: 2015-01-20T12:54:43Z + +[Term] +id: GO:1990611 +name: regulation of cytoplasmic translational initiation in response to stress +namespace: biological_process +def: "Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [PMID:16278445] +is_a: GO:0043558 ! regulation of translational initiation in response to stress +is_a: GO:1990497 ! regulation of cytoplasmic translation in response to stress +created_by: vw +creation_date: 2015-01-20T13:04:14Z + +[Term] +id: GO:1990612 +name: Sad1-Kms1 LINC complex +namespace: cellular_component +def: "A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair." [GOC:vw, PMID:24943839, PMID:24947240] +is_a: GO:0034993 ! meiotic nuclear membrane microtubule tethering complex +is_a: GO:1990391 ! DNA repair complex +created_by: jl +creation_date: 2015-01-20T13:10:49Z + +[Term] +id: GO:1990613 +name: mitochondrial membrane fusion +namespace: biological_process +def: "The joining of two lipid bilayers that surround the mitochondria." [PMID:12052774] +is_a: GO:0007006 ! mitochondrial membrane organization +is_a: GO:0090174 ! organelle membrane fusion +intersection_of: GO:0061025 ! membrane fusion +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: vw +creation_date: 2015-01-21T06:58:18Z + +[Term] +id: GO:1990615 +name: Kelch-containing formin regulatory complex +namespace: cellular_component +def: "A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p." [PMID:24828508] +synonym: "Bud14-Kel1-Kel2 complex" NARROW [] +synonym: "KFRC complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: mcc +creation_date: 2015-01-21T18:48:51Z + +[Term] +id: GO:1990616 +name: magnesium ion export from mitochondrion +namespace: biological_process +def: "The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore." [PMID:25585246] +synonym: "magnesium ion efflux from mitochondrion" EXACT [] +is_a: GO:0045016 ! mitochondrial magnesium ion transmembrane transport +created_by: mcc +creation_date: 2015-01-21T22:06:42Z + +[Term] +id: GO:1990617 +name: CHOP-ATF4 complex +namespace: cellular_component +def: "A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits." [GOC:bf, GOC:PARL, PMID:18940792] +synonym: "ATF4-CHOP heterodimer" EXACT [PMID:18940792] +synonym: "CHOP-ATF4 heterodimer" EXACT [PMID:18940792] +synonym: "CHOP-CREB-2 complex" EXACT [PMID:11478948] +synonym: "CHOP/ATF4 complex" EXACT [PMID:18940792] +synonym: "GADD153-ATF4 complex" EXACT [GOC:bf] +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: bf +creation_date: 2015-01-22T11:29:51Z + +[Term] +id: GO:1990618 +name: obsolete ANPR-A:ANP complex +namespace: cellular_component +def: "OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. Therefore, ANPR-A:ANP complex plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis." [GOC:ame, PMID:15117952] +comment: An example of this is [ANPR-A:ANP] in [rat] (P18910:P01161-PRO_0000391785) in PMID:15117952 (inferred from direct assay). +synonym: "ANPR-A:ANP complex" EXACT [] +xref: IntAct:EBI-10093340 +is_obsolete: true +created_by: ame +creation_date: 2015-01-23T15:17:47Z + +[Term] +id: GO:1990619 +name: histone H3-K9 deacetylation +namespace: biological_process +def: "The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone." [PMID:25002536] +is_a: GO:0070932 ! histone H3 deacetylation +created_by: al +creation_date: 2015-01-23T17:27:16Z + +[Term] +id: GO:1990620 +name: ANPR-A receptor complex +namespace: cellular_component +def: "A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure." [GOC:ame, PMID:15117952] +comment: An example of this is Npr1 in rat (UniProt symbol P18910) in PMID:15117952 (inferred from direct assay). +synonym: "NPR1 receptor complex" RELATED [] +xref: IntAct:EBI-10093340 +is_a: GO:0043235 ! receptor complex +created_by: ame +creation_date: 2015-01-28T16:03:22Z + +[Term] +id: GO:1990621 +name: ESCRT IV complex +namespace: cellular_component +def: "An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1." [GOC:bhm, GOC:ha, PMID:20653365, PMID:20696398, PMID:21925211, PMID:24456136, PMID:25164817, PMID:26775243] +synonym: "ESCRT-IV" EXACT [] +synonym: "vacuolar protein sorting-associated complex" RELATED [] +synonym: "Vps4 complex" RELATED [] +synonym: "Vps4-Vta1 complex" NARROW [] +synonym: "VPS4A-VPS4B" NARROW [] +synonym: "VPS4A/B complex" NARROW [] +synonym: "Vta1-Vps4 complex" RELATED [] +xref: IntAct:EBI-11565638 +is_a: GO:0036452 ! ESCRT complex +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1904949 ! ATPase complex +relationship: part_of GO:0010008 ! endosome membrane +created_by: pr +creation_date: 2015-01-29T10:02:30Z + +[Term] +id: GO:1990622 +name: CHOP-ATF3 complex +namespace: cellular_component +def: "A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits." [GOC:bf, GOC:PARL, PMID:8622660] +synonym: "ATF3-CHOP complex" EXACT [GOC:bf] +synonym: "CHOP-ATF3 heterodimer" EXACT [GOC:bf] +synonym: "CHOP-ATF3 heterodimeric complex" EXACT [GOC:bf] +synonym: "GADD153-ATF3 complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-01-29T16:43:19Z + +[Term] +id: GO:1990623 +name: Herring body +namespace: cellular_component +def: "The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively." [ISBN:0199652473, Wikipedia:Herring_bodies] +synonym: "neurosecretory body" EXACT [] +is_a: GO:0043679 ! axon terminus +created_by: cls +creation_date: 2015-01-29T21:11:54Z + +[Term] +id: GO:1990624 +name: guanyl nucleotide exchange factor inhibitor activity +namespace: molecular_function +def: "Stops, prevents or reduces the activity of a guanyl nucleotide exchange factor." [GOC:vw, PMID:25635048] +is_a: GO:0030234 ! enzyme regulator activity +created_by: vw +creation_date: 2015-01-31T15:17:01Z + +[Term] +id: GO:1990625 +name: negative regulation of cytoplasmic translational initiation in response to stress +namespace: biological_process +def: "Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:vw, PMID:12242291] +is_a: GO:0032057 ! negative regulation of translational initiation in response to stress +is_a: GO:1990611 ! regulation of cytoplasmic translational initiation in response to stress +is_a: GO:2000766 ! negative regulation of cytoplasmic translation +created_by: vw +creation_date: 2015-01-31T21:25:56Z + +[Term] +id: GO:1990626 +name: mitochondrial outer membrane fusion +namespace: biological_process +def: "The membrane organization process that joins two mitochondrial outer membranes to form a single membrane." [GOC:vw, PMID:21385840] +is_a: GO:0007008 ! outer mitochondrial membrane organization +is_a: GO:1990613 ! mitochondrial membrane fusion +created_by: vw +creation_date: 2015-02-02T11:32:17Z + +[Term] +id: GO:1990627 +name: mitochondrial inner membrane fusion +namespace: biological_process +def: "The membrane organization process that joins two mitochondrial inner membranes to form a single membrane." [GOC:vw, PMID:17055438] +is_a: GO:0007007 ! inner mitochondrial membrane organization +is_a: GO:1990613 ! mitochondrial membrane fusion +created_by: vw +creation_date: 2015-02-02T11:37:56Z + +[Term] +id: GO:1990628 +name: obsolete Sigma-E factor negative regulation complex +namespace: cellular_component +def: "OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell." [GOC:bhm, PMID:20190044] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "RseA-RseB-RpoE complex" RELATED [] +synonym: "Sigma-E factor negative regulation complex" EXACT [] +xref: IntAct:EBI-9019066 +is_obsolete: true +created_by: bhm +creation_date: 2015-02-04T15:38:37Z + +[Term] +id: GO:1990629 +name: phospholamban complex +namespace: cellular_component +def: "A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels." [GOC:ame, PMID:16043693] +comment: An example of this is PLN in human (UniProt symbol P26678) in PMID:16043693 (inferred from direct assay). +synonym: "cardiac phospholamban complex" EXACT [] +synonym: "cardiac PLB complex" RELATED [] +synonym: "cardiac PLN complex" RELATED [] +xref: IntAct:EBI-10104734 +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0033017 ! sarcoplasmic reticulum membrane +created_by: ame +creation_date: 2015-02-05T14:12:36Z + +[Term] +id: GO:1990630 +name: IRE1-RACK1-PP2A complex +namespace: cellular_component +def: "A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A." [GOC:bf, GOC:PARL, PMID:20103773] +synonym: "ERN1-RACK1-PP2A complex" RELATED [HGNC:3449] +synonym: "IRE1alpha-RACK1-PP2A complex" NARROW [GOC:bf, PMID:20103773] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-02-05T15:37:58Z + +[Term] +id: GO:1990631 +name: ErbB-4 class receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-4/HER4." [GOC:sl, PMID:18523588] +synonym: "HER4 receptor binding" EXACT [] +is_a: GO:0005102 ! signaling receptor binding +created_by: sl +creation_date: 2015-02-06T23:28:49Z + +[Term] +id: GO:1990632 +name: branching involved in submandibular gland morphogenesis +namespace: biological_process +def: "The process in which the branching structure of the submandibular gland is generated and organized." [PMID:15063181, PMID:20890964] +synonym: "submandibular gland branching morphogenesis" EXACT [PMID:20890964] +synonym: "submandibular gland ductal branching" EXACT [PMID:20890964] +is_a: GO:0060445 ! branching involved in salivary gland morphogenesis +created_by: cls +creation_date: 2015-02-10T14:40:01Z + +[Term] +id: GO:1990633 +name: mutator focus +namespace: cellular_component +def: "A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules." [GOC:kmv, PMID:22713602, PMID:25635455] +is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule +relationship: part_of GO:0048471 ! perinuclear region of cytoplasm +created_by: kmv +creation_date: 2015-02-10T20:24:02Z + +[Term] +id: GO:1990634 +name: protein phosphatase 5 binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the enzyme protein phosphatase 5." [PMID:8943293] +synonym: "protein phosphatase T binding" EXACT [] +is_a: GO:0019903 ! protein phosphatase binding +created_by: sl +creation_date: 2015-02-10T21:30:41Z + +[Term] +id: GO:1990635 +name: proximal dendrite +namespace: cellular_component +def: "The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma)." [GOC:aruk, GOC:bc, PMID:16899232] +is_a: GO:0030425 ! dendrite +created_by: sl +creation_date: 2015-02-10T22:57:16Z + +[Term] +id: GO:1990636 +name: reproductive senescence +namespace: biological_process +def: "A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones." [PMID:24914937, PMID:25523082] +is_a: GO:0010259 ! multicellular organism aging +created_by: sl +creation_date: 2015-02-10T23:17:56Z + +[Term] +id: GO:1990637 +name: response to prolactin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation." [PMID:7760850] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-02-10T23:47:11Z + +[Term] +id: GO:1990638 +name: response to granulocyte colony-stimulating factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus." [PMID:9488469] +synonym: "response to G-CSF" EXACT [] +is_a: GO:0034097 ! response to cytokine +created_by: sl +creation_date: 2015-02-11T00:02:33Z + +[Term] +id: GO:1990639 +name: obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate." [PMID:11348594] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "inositol-3,4,5-trisphosphate 5-phosphatase activity" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2015-02-11T15:58:56Z + +[Term] +id: GO:1990640 +name: inositol-2,4,5-triphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate." [PMID:15316017] +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity +created_by: al +creation_date: 2015-02-11T18:20:40Z + +[Term] +id: GO:1990641 +name: response to iron ion starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion." [PMID:16208485] +is_a: GO:0042594 ! response to starvation +created_by: sl +creation_date: 2015-02-11T18:43:28Z + +[Term] +id: GO:1990642 +name: obsolete response to castration +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads." [PMID:11255226] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to castration" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2015-02-11T18:53:04Z + +[Term] +id: GO:1990643 +name: cellular response to granulocyte colony-stimulating factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus." [PMID:9488469] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:1990638 ! response to granulocyte colony-stimulating factor +created_by: sl +creation_date: 2015-02-11T19:22:44Z + +[Term] +id: GO:1990644 +name: microtubule site clamp +namespace: molecular_function +def: "The binding activity of a molecule that attaches the spindle microtubules to the kinetochore." [PMID:20723757] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +created_by: vw +creation_date: 2015-02-13T15:50:13Z + +[Term] +id: GO:1990645 +name: obsolete phosphorylase dephosphorylation +namespace: biological_process +def: "OBSOLETE. The modification of phosphorylases by removal of phosphate groups." [PMID:8602837] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "phosphorylase dephosphorylation" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2015-02-18T16:39:50Z + +[Term] +id: GO:1990646 +name: cellular response to prolactin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus." [PMID:7760850] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1990637 ! response to prolactin +created_by: sl +creation_date: 2015-02-18T16:53:11Z + +[Term] +id: GO:1990647 +name: C/EBP complex +namespace: cellular_component +def: "A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities." [GOC:bhm, GOC:pad, GOC:PARL, PMID:8657121] +comment: An example of this is Cebpa in rat (P05554) in PMID:8657121 (inferred from direct assay). +synonym: "C/EBP homodimer complex" EXACT [] +synonym: "C/EBP transcription factor complex" EXACT [] +synonym: "C/EBPalpha complex" NARROW [] +synonym: "C/EBPalpha homodimer complex" NARROW [] +synonym: "C/EBPbeta complex" NARROW [] +synonym: "C/EBPbeta homodimer complex" NARROW [] +xref: IntAct:EBI-10637780 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: bhm +creation_date: 2015-02-19T11:00:09Z + +[Term] +id: GO:1990648 +name: inositol-4,5,6-triphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate." [GOC:al, PMID:15316017] +is_a: GO:0046030 ! inositol trisphosphate phosphatase activity +created_by: al +creation_date: 2015-02-23T11:10:51Z + +[Term] +id: GO:1990649 +name: inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate." [GOC:al, PMID:15316017] +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity +created_by: al +creation_date: 2015-02-23T11:12:10Z + +[Term] +id: GO:1990650 +name: inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate." [GOC:al, PMID:15316017] +is_a: GO:0052743 ! inositol tetrakisphosphate phosphatase activity +created_by: al +creation_date: 2015-02-23T11:14:17Z + +[Term] +id: GO:1990651 +name: inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate." [GOC:al, PMID:15316017] +is_a: GO:0052827 ! inositol pentakisphosphate phosphatase activity +created_by: al +creation_date: 2015-02-23T11:17:19Z + +[Term] +id: GO:1990652 +name: obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage." [PMID:23695302] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" EXACT [] +is_obsolete: true +created_by: al +creation_date: 2015-02-23T11:25:51Z + +[Term] +id: GO:1990653 +name: obsolete monounsaturated fatty acid biosynthetic process +namespace: biological_process +def: "OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids." [GOC:hjd, PMID:16443825] +comment: For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast. +is_obsolete: true +created_by: hjd +creation_date: 2015-02-23T18:59:15Z + +[Term] +id: GO:1990654 +name: sebum secreting cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum." [GOC:hjd, PMID:16901790, PMID:18474083] +synonym: "sebocyte proliferation" RELATED [GOC:dph] +is_a: GO:0008283 ! cell population proliferation +created_by: hjd +creation_date: 2015-02-23T19:43:49Z + +[Term] +id: GO:1990655 +name: 4 iron, 3 sulfur cluster binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria." [GOC:am, PMID:23267108] +synonym: "4Fe-3S cluster binding" RELATED [] +is_a: GO:0051536 ! iron-sulfur cluster binding +created_by: pr +creation_date: 2015-02-24T17:07:23Z + +[Term] +id: GO:1990656 +name: t-SNARE clustering +namespace: biological_process +def: "The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies." [PMID:22528485] +is_a: GO:0072657 ! protein localization to membrane +created_by: sl +creation_date: 2015-02-25T00:18:33Z + +[Term] +id: GO:1990657 +name: iNOS-S100A8/A9 complex +namespace: cellular_component +def: "A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine." [GOC:bhm, PMID:25417112] +comment: An example of this is NOS2 in human (UniProt symbol P35228) in PMID:25417112 (inferred from direct assay). +xref: IntAct:EBI-10105915 +xref: IntAct:EBI-10106087 +is_a: GO:1903958 ! nitric-oxide synthase complex +is_a: GO:1990658 ! transnitrosylase complex +created_by: bhm +creation_date: 2015-02-25T11:00:49Z + +[Term] +id: GO:1990658 +name: transnitrosylase complex +namespace: cellular_component +def: "A transferase complex which is capable of transferring nitrogenous groups from one component to another." [GOC:bhm, PMID:25417112] +comment: An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay). +synonym: "transferase complex, transferring nitrogenous groups" EXACT [] +is_a: GO:1990234 ! transferase complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bhm +creation_date: 2015-02-25T11:17:17Z + +[Term] +id: GO:1990659 +name: sequestering of manganese ion +namespace: biological_process +def: "The process of binding or confining manganese ions such that they are separated from other components of a biological system." [GOC:bhm, PMID:25417112] +comment: An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay). +synonym: "manganese ion retention" EXACT [] +synonym: "manganese ion sequestering" EXACT [] +synonym: "manganese ion sequestration" EXACT [] +synonym: "manganese ion storage" EXACT [] +synonym: "retention of manganese ion" EXACT [] +synonym: "sequestration of manganese ion" EXACT [] +synonym: "storage of manganese ion" EXACT [] +is_a: GO:0051238 ! sequestering of metal ion +is_a: GO:0051651 ! maintenance of location in cell +relationship: part_of GO:0030026 ! cellular manganese ion homeostasis +created_by: bhm +creation_date: 2015-02-25T11:41:12Z + +[Term] +id: GO:1990660 +name: calprotectin complex +namespace: cellular_component +def: "A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways." [GOC:bhm, PMID:25417112] +comment: An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay). +synonym: "calprotectin heterodimer" NARROW [] +xref: IntAct:EBI-10098135 +xref: IntAct:EBI-10098681 +xref: IntAct:EBI-10098713 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2015-02-25T14:03:17Z + +[Term] +id: GO:1990661 +name: S100A8 complex +namespace: cellular_component +def: "A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4)." [GOC:bhm, PMID:25417112] +comment: An example of this is S100A8 in human (UniProt symbol P27005) in PMID:25417112 (inferred from direct assay). +synonym: "S100A8 homodimer" EXACT [] +xref: IntAct:EBI-10098921 +xref: IntAct:EBI-10099454 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2015-02-25T15:33:32Z + +[Term] +id: GO:1990662 +name: S100A9 complex +namespace: cellular_component +def: "A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility." [GOC:bhm, PMID:15642721] +comment: An example of this is S100A9 in human (UniProt symbol P06702) in PMID:15642721 (inferred from direct assay). +synonym: "S100A9 homodimer" EXACT [] +xref: IntAct:EBI-10099500 +xref: IntAct:EBI-10099571 +is_a: GO:1902495 ! transmembrane transporter complex +created_by: bhm +creation_date: 2015-02-25T15:55:48Z + +[Term] +id: GO:1990663 +name: dihydroorotate dehydrogenase (fumarate) activity +namespace: molecular_function +def: "Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate." [PMID:1409592] +xref: EC:1.3.98.1 +is_a: GO:0004152 ! dihydroorotate dehydrogenase activity +created_by: al +creation_date: 2015-02-26T15:47:30Z + +[Term] +id: GO:1990664 +name: Nkx-2.5 complex +namespace: cellular_component +def: "A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes." [GOC:ame, PMID:22849347] +comment: An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay). +synonym: "Nkx-2.5 homodimer complex" NARROW [] +synonym: "NKX.2-5 homodimer complex" RELATED [] +synonym: "NKX2.5 complex" RELATED [] +synonym: "NKX2E homodimer complex" RELATED [] +xref: IntAct:EBI-10636829 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: ame +creation_date: 2015-02-27T12:22:06Z + +[Term] +id: GO:1990665 +name: AnxA2-p11 complex +namespace: cellular_component +def: "A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10)." [GOC:bf, GOC:BHF, GOC:nc, PMID:18799458, PMID:23483454] +synonym: "(A2.p11)2 complex" EXACT [PMID:23483454] +synonym: "(p11)2.(AnxA2)2 complex" EXACT [PMID:18799458] +synonym: "Annexin A2 tetramer" RELATED [PMID:23483454] +synonym: "Annexin A2-p11 complex" EXACT [GOC:bf] +synonym: "AnxA2.p11 complex" EXACT [PMID:18799458] +synonym: "AnxA2:S100A10 heterotetramer" EXACT [PMID:23483454] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-03-02T10:07:42Z + +[Term] +id: GO:1990666 +name: PCSK9-LDLR complex +namespace: cellular_component +def: "A protein complex consisting of the serine protease PCSK9 (Proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway." [GOC:BHF, GOC:nc, PMID:18250299, PMID:24440079] +synonym: "PCSK9.LDLR complex" EXACT [PMID:18799458] +synonym: "PCSK9/LDL-R complex" EXACT [PMID:24440079] +synonym: "PCSK9:EGF-A complex" RELATED [PMID:18250299] +synonym: "PCSK9:low-density lipoprotein receptor complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-03-02T10:19:15Z + +[Term] +id: GO:1990667 +name: PCSK9-AnxA2 complex +namespace: cellular_component +def: "A protein complex consisting of the serine protease PCSK9 (Proprotein convertase subtilisin/kexin-9) and Annexin A2 (AnxA2)." [GOC:BHF, GOC:nc, PMID:22848640] +synonym: "PCSK9-Annexin A2 complex" EXACT [GOC:bf] +synonym: "PCSK9.AnxA2 complex" EXACT [PMID:18799458] +synonym: "PCSK9:ANXA2 complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-03-02T10:33:09Z + +[Term] +id: GO:1990668 +name: vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane" EXACT [] +synonym: "vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane" EXACT [] +synonym: "vesicle fusion with ER-Golgi intermediate compartment membrane" EXACT [] +synonym: "vesicle fusion with ERGIC membrane" EXACT [] +is_a: GO:0006906 ! vesicle fusion +created_by: bhm +creation_date: 2015-03-02T11:17:32Z + +[Term] +id: GO:1990669 +name: endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane" EXACT [] +synonym: "ER-Golgi intermediate compartment derived vesicle fusion with ER membrane" EXACT [] +is_a: GO:0048279 ! vesicle fusion with endoplasmic reticulum +relationship: part_of GO:0006890 ! retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +created_by: bhm +creation_date: 2015-03-02T11:21:43Z + +[Term] +id: GO:1990670 +name: vesicle fusion with Golgi cis cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles." [GOC:bhm, PMID:16038056, PMID:24119662] +is_a: GO:0006906 ! vesicle fusion +created_by: bhm +creation_date: 2015-03-02T11:25:19Z + +[Term] +id: GO:1990671 +name: vesicle fusion with Golgi medial cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles." [GOC:bhm, PMID:16038056, PMID:24119662] +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +created_by: bhm +creation_date: 2015-03-02T11:31:01Z + +[Term] +id: GO:1990672 +name: medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +is_a: GO:0048210 ! Golgi vesicle fusion to target membrane +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: part_of GO:0048219 ! inter-Golgi cisterna vesicle-mediated transport +created_by: bhm +creation_date: 2015-03-02T11:34:39Z + +[Term] +id: GO:1990673 +name: intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +namespace: cellular_component +def: "The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane" EXACT [] +is_a: GO:0031300 ! intrinsic component of organelle membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0033116 ! endoplasmic reticulum-Golgi intermediate compartment membrane +relationship: part_of GO:0033116 ! endoplasmic reticulum-Golgi intermediate compartment membrane +created_by: bhm +creation_date: 2015-03-02T11:44:46Z + +[Term] +id: GO:1990674 +name: Golgi cis cisterna membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "cis-Golgi cisterna membrane" EXACT [] +is_a: GO:0032580 ! Golgi cisterna membrane +relationship: part_of GO:0000137 ! Golgi cis cisterna +created_by: bhm +creation_date: 2015-03-02T11:48:00Z + +[Term] +id: GO:1990675 +name: Golgi medial cisterna membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "medial-Golgi cisterna membrane" EXACT [] +is_a: GO:0032580 ! Golgi cisterna membrane +relationship: part_of GO:0005797 ! Golgi medial cisterna +created_by: bhm +creation_date: 2015-03-02T11:50:29Z + +[Term] +id: GO:1990676 +name: Golgi trans cisterna membrane +namespace: cellular_component +def: "The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "trans-Golgi cisterna membrane" EXACT [] +is_a: GO:0032580 ! Golgi cisterna membrane +relationship: part_of GO:0000138 ! Golgi trans cisterna +created_by: bhm +creation_date: 2015-03-02T11:53:35Z + +[Term] +id: GO:1990677 +name: mitochondrial inner membrane assembly complex +namespace: cellular_component +def: "A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion." [GOC:bhm, PMID:24942160] +comment: An example of this is INA22 in Saccharomyces cerevisiae (P40576) in PMID:24942160 (inferred from direct assay/mutant phenotype/etc.). +synonym: "INAC complex" EXACT [] +synonym: "inner membrane assembly complex" BROAD [] +is_a: GO:0098800 ! inner mitochondrial membrane protein complex +created_by: bhm +creation_date: 2015-03-02T13:14:52Z + +[Term] +id: GO:1990678 +name: histone H4-K16 deacetylation +namespace: biological_process +def: "The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone." [PMID:17446861] +is_a: GO:0070933 ! histone H4 deacetylation +created_by: al +creation_date: 2015-03-02T15:25:56Z + +[Term] +id: GO:1990679 +name: histone H4-K12 deacetylation +namespace: biological_process +def: "The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone." [PMID:17446861] +is_a: GO:0070933 ! histone H4 deacetylation +created_by: al +creation_date: 2015-03-02T15:40:44Z + +[Term] +id: GO:1990680 +name: response to melanocyte-stimulating hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates." [PMID:17036007] +synonym: "response to MSH" EXACT [] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-03-02T20:49:46Z + +[Term] +id: GO:1990682 +name: CSF1-CSF1R complex +namespace: cellular_component +def: "A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand." [GOC:bf, GOC:BHF, GOC:nc, PMID:19017797] +synonym: "CSF1:C-FMS complex" EXACT [HGNC:2432, HGNC:2433] +synonym: "M-CSF:C-FMS complex" RELATED [GOC:nc] +synonym: "M-CSF:CSF1R complex" RELATED [HGNC:2432, HGNC:2433] +synonym: "M-CSF:FMS complex" EXACT [PMID:19017797] +synonym: "macrophage colony-stimulating factor:receptor complex" EXACT [GOC:bf] +is_a: GO:0032991 ! protein-containing complex +created_by: bf +creation_date: 2015-03-10T12:23:03Z + +[Term] +id: GO:1990683 +name: DNA double-strand break attachment to nuclear envelope +namespace: biological_process +def: "A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs." [PMID:24943839] +is_a: GO:0097240 ! chromosome attachment to the nuclear envelope +created_by: vw +creation_date: 2015-03-10T16:36:21Z + +[Term] +id: GO:1990684 +name: protein-lipid-RNA complex +namespace: cellular_component +def: "A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other." [GOC:vesicles, PMID:21423178, PMID:22028337, PMID:23559634] +comment: Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle' or GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs. +synonym: "miRNA-lipoprotein complex" RELATED [] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2015-03-11T14:24:33Z + +[Term] +id: GO:1990685 +name: HDL-containing protein-lipid-RNA complex +namespace: cellular_component +def: "A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other." [GOC:vesicles, PMID:21423178, PMID:23559634] +comment: Examples of HDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoproteins (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle', which describes complexes of proteins and lipids only, without RNAs. +is_a: GO:1990684 ! protein-lipid-RNA complex +created_by: pr +creation_date: 2015-03-11T14:56:52Z + +[Term] +id: GO:1990686 +name: LDL-containing protein-lipid-RNA complex +namespace: cellular_component +def: "A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other." [GOC:vesicles, PMID:23559634] +comment: Examples of LDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs. +is_a: GO:1990684 ! protein-lipid-RNA complex +created_by: pr +creation_date: 2015-03-11T15:11:34Z + +[Term] +id: GO:1990687 +name: endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane" EXACT [] +synonym: "ER-derived vesicle fusion with ERGIC membrane" EXACT [] +is_a: GO:1990668 ! vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +relationship: part_of GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: bhm +creation_date: 2015-03-12T09:31:45Z + +[Term] +id: GO:1990688 +name: Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "Golgi vesicle fusion with ER-Golgi intermediate compartment membrane" EXACT [] +synonym: "Golgi vesicle fusion with ERGIC membrane" EXACT [] +is_a: GO:1990668 ! vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +relationship: part_of GO:0006890 ! retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +created_by: bhm +creation_date: 2015-03-12T09:34:21Z + +[Term] +id: GO:1990689 +name: endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane" EXACT [] +synonym: "ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane" EXACT [] +synonym: "ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane" EXACT [] +synonym: "ERGIC-derived vesicle fusion with cis-Golgi cisterna membrane" EXACT [] +synonym: "ERGIC-derived vesicle fusion with Golgi cis cisterna membrane" EXACT [] +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +is_a: GO:1990670 ! vesicle fusion with Golgi cis cisterna membrane +relationship: part_of GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport +created_by: bhm +creation_date: 2015-03-12T09:41:48Z + +[Term] +id: GO:1990690 +name: Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane" EXACT [] +is_a: GO:0048210 ! Golgi vesicle fusion to target membrane +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: part_of GO:0000301 ! retrograde transport, vesicle recycling within Golgi +created_by: bhm +creation_date: 2015-03-12T09:47:03Z + +[Term] +id: GO:1990691 +name: cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane" EXACT [] +is_a: GO:0048210 ! Golgi vesicle fusion to target membrane +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: part_of GO:0048219 ! inter-Golgi cisterna vesicle-mediated transport +created_by: bhm +creation_date: 2015-03-12T09:51:01Z + +[Term] +id: GO:1990692 +name: trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane +namespace: biological_process +def: "The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane" EXACT [] +is_a: GO:0048210 ! Golgi vesicle fusion to target membrane +is_a: GO:0048280 ! vesicle fusion with Golgi apparatus +relationship: part_of GO:0000301 ! retrograde transport, vesicle recycling within Golgi +created_by: bhm +creation_date: 2015-03-12T09:54:02Z + +[Term] +id: GO:1990693 +name: intrinsic component of Golgi cis cisterna membrane +namespace: cellular_component +def: "The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "intrinsic component of cis-Golgi cisterna membrane" EXACT [] +is_a: GO:0031228 ! intrinsic component of Golgi membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:1990674 ! Golgi cis cisterna membrane +relationship: part_of GO:1990674 ! Golgi cis cisterna membrane +created_by: bhm +creation_date: 2015-03-12T10:24:07Z + +[Term] +id: GO:1990694 +name: intrinsic component of Golgi medial cisterna membrane +namespace: cellular_component +def: "The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "intrinsic component of medial-Golgi cisterna membrane" EXACT [] +is_a: GO:0031228 ! intrinsic component of Golgi membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:1990675 ! Golgi medial cisterna membrane +relationship: part_of GO:1990675 ! Golgi medial cisterna membrane +created_by: bhm +creation_date: 2015-03-12T10:29:12Z + +[Term] +id: GO:1990695 +name: intrinsic component of Golgi trans cisterna membrane +namespace: cellular_component +def: "The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "intrinsic component of trans-Golgi cisterna membrane" EXACT [] +is_a: GO:0031228 ! intrinsic component of Golgi membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:1990676 ! Golgi trans cisterna membrane +relationship: part_of GO:1990676 ! Golgi trans cisterna membrane +created_by: bhm +creation_date: 2015-03-12T10:36:02Z + +[Term] +id: GO:1990696 +name: USH2 complex +namespace: cellular_component +def: "A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7." [GOC:krc, PMID:25406310] +synonym: "USH2 quaternary protein complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: krc +creation_date: 2015-03-12T17:29:18Z + +[Term] +id: GO:1990697 +name: protein depalmitoleylation +namespace: biological_process +def: "The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein." [PMID:25731175] +is_a: GO:0035601 ! protein deacylation +is_a: GO:0042159 ! lipoprotein catabolic process +created_by: sp +creation_date: 2015-03-13T08:55:31Z + +[Term] +id: GO:1990698 +name: palmitoleoyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule." [PMID:17141155, PMID:25731175] +is_a: GO:0016747 ! transferase activity, transferring acyl groups other than amino-acyl groups +created_by: sp +creation_date: 2015-03-13T08:58:25Z + +[Term] +id: GO:1990699 +name: palmitoleyl hydrolase activity +namespace: molecular_function +def: "Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate." [PMID:25731175] +is_a: GO:0052689 ! carboxylic ester hydrolase activity +created_by: sp +creation_date: 2015-03-13T09:00:05Z + +[Term] +id: GO:1990700 +name: nucleolar chromatin organization +namespace: biological_process +def: "Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin." [PMID:18362178] +synonym: "establishment or maintenance of nucleolar chromatin architecture" EXACT [] +synonym: "nucleolar chromatin organisation" EXACT [] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0006325 ! chromatin organization +created_by: mah +creation_date: 2015-03-16T12:11:01Z + +[Term] +id: GO:1990701 +name: integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +namespace: cellular_component +def: "The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "integral component of endoplasmic reticulum-Golgi intermediate compartment membrane" EXACT [] +synonym: "integral component of ER-Golgi intermediate compartment membrane" EXACT [] +synonym: "integral component of ERGIC membrane" EXACT [] +is_a: GO:0031301 ! integral component of organelle membrane +is_a: GO:1990673 ! intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:0033116 ! endoplasmic reticulum-Golgi intermediate compartment membrane +created_by: bhm +creation_date: 2015-03-16T15:57:36Z + +[Term] +id: GO:1990702 +name: integral component of Golgi cis cisterna membrane +namespace: cellular_component +def: "The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "integral component of cis-Golgi cisterna membrane" EXACT [] +is_a: GO:0030173 ! integral component of Golgi membrane +is_a: GO:1990693 ! intrinsic component of Golgi cis cisterna membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:1990674 ! Golgi cis cisterna membrane +created_by: bhm +creation_date: 2015-03-16T16:03:21Z + +[Term] +id: GO:1990703 +name: integral component of Golgi medial cisterna membrane +namespace: cellular_component +def: "The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "integral component of medial-Golgi cisterna membrane" EXACT [] +is_a: GO:0030173 ! integral component of Golgi membrane +is_a: GO:1990694 ! intrinsic component of Golgi medial cisterna membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:1990675 ! Golgi medial cisterna membrane +created_by: bhm +creation_date: 2015-03-16T16:05:25Z + +[Term] +id: GO:1990704 +name: integral component of Golgi trans cisterna membrane +namespace: cellular_component +def: "The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:bhm, PMID:16038056, PMID:24119662] +synonym: "integral component of trans-Golgi cisterna membrane" EXACT [] +is_a: GO:0030173 ! integral component of Golgi membrane +is_a: GO:1990695 ! intrinsic component of Golgi trans cisterna membrane +intersection_of: GO:0016021 ! integral component of membrane +intersection_of: part_of GO:1990676 ! Golgi trans cisterna membrane +created_by: bhm +creation_date: 2015-03-16T16:08:07Z + +[Term] +id: GO:1990705 +name: cholangiocyte proliferation +namespace: biological_process +def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010] +synonym: "hepatoblast proliferation" EXACT [] +is_a: GO:0050673 ! epithelial cell proliferation +creation_date: 2015-03-16T23:23:50Z + +[Term] +id: GO:1990706 +name: MAD1 complex +namespace: cellular_component +def: "A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C)." [GOC:bhm, intAct:EBI-10691224, PMID:22493223, PMID:22898774] +synonym: "MAD1 homodimer" EXACT [] +xref: IntAct:EBI-10691160 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2015-03-17T15:49:16Z + +[Term] +id: GO:1990707 +name: nuclear subtelomeric heterochromatin +namespace: cellular_component +alt_id: GO:1990421 +def: "Heterochromatic regions of the chromosome found at the subtelomeric regions of a chromosome in the nucleus." [PMID:18761674, PMID:7660126] +synonym: "sub-telomeric heterochromatin" RELATED [] +synonym: "subtelomeric heterochromatin" RELATED [] +is_a: GO:0000784 ! nuclear chromosome, telomeric region +is_a: GO:0005720 ! nuclear heterochromatin +is_a: GO:0099115 ! chromosome, subtelomeric region +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19086 xsd:anyURI +created_by: vw +creation_date: 2014-07-18T13:32:59Z + +[Term] +id: GO:1990708 +name: conditioned place preference +namespace: biological_process +def: "The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug." [PMID:21549821] +is_a: GO:0008306 ! associative learning +created_by: sl +creation_date: 2015-03-18T20:28:59Z + +[Term] +id: GO:1990709 +name: presynaptic active zone organization +namespace: biological_process +def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone." [GOC:pr, PMID:16865347, PMID:17068967] +synonym: "presynaptic active zone organisation" EXACT [] +is_a: GO:0016043 ! cellular component organization +relationship: part_of GO:0050808 ! synapse organization +created_by: pr +creation_date: 2015-03-20T10:16:24Z + +[Term] +id: GO:1990710 +name: MutS complex +namespace: cellular_component +def: "A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations." [GOC:bhm, PMID:21666597] +comment: An example of this is MutS in E. coli (UniProt symbol P23909) in PMID:21666597 (inferred from physical interaction). +synonym: "MutS mismatch repair complex" EXACT [] +xref: IntAct:EBI-10705937 +is_a: GO:0032300 ! mismatch repair complex +is_a: GO:1904949 ! ATPase complex +created_by: bhm +creation_date: 2015-03-25T11:42:56Z + +[Term] +id: GO:1990711 +name: beta-catenin-ICAT complex +namespace: cellular_component +def: "Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex." [GOC:bhm, PMID:12408824] +comment: An example of this is Catenin beta-1 in human (UniProt symbol P35222) in PMID:12408824 (inferred from physical interaction). +synonym: "Beta-catenin-ICAT complex" EXACT [] +synonym: "CTNNB1-CTNNBIP1 complex" EXACT [] +xref: IntAct:EBI-10691252 +xref: IntAct:EBI-10705284 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: bhm +creation_date: 2015-03-25T21:08:11Z + +[Term] +id: GO:1990712 +name: HFE-transferrin receptor complex +namespace: cellular_component +def: "A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription." [GOC:BHF, GOC:kom, PMID:25147378] +is_a: GO:0098802 ! plasma membrane signaling receptor complex +created_by: pr +creation_date: 2015-03-26T13:03:27Z + +[Term] +id: GO:1990713 +name: survivin complex +namespace: cellular_component +def: "A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC)." [GOC:bhm, PMID:10949038] +comment: An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction). +synonym: "Baculoviral IAP repeat-containing protein 5 complex" EXACT [] +synonym: "survivin homodimer complex" NARROW [] +xref: IntAct:EBI-10714791 +xref: IntAct:EBI-10727115 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005654 ! nucleoplasm +created_by: bhm +creation_date: 2015-03-26T14:21:46Z + +[Term] +id: GO:1990714 +name: hydroxyproline O-galactosyltransferase activity +namespace: molecular_function +def: "Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone." [PMID:25600942] +synonym: "HPGT" EXACT [] +is_a: GO:0008378 ! galactosyltransferase activity +created_by: tb +creation_date: 2015-03-26T23:22:09Z + +[Term] +id: GO:1990715 +name: mRNA CDS binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the coding sequence (CDS) of an mRNA molecule." [GOC:kmv, PMID:25805859, SO:0000316] +synonym: "mRNA coding region binding" EXACT [] +synonym: "mRNA coding sequence binding" EXACT [] +is_a: GO:0003729 ! mRNA binding +created_by: kmv +creation_date: 2015-03-27T20:59:49Z + +[Term] +id: GO:1990716 +name: axonemal central apparatus +namespace: cellular_component +def: "Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules." [GOC:cilia, PMID:21586547, PMID:9295136] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005930 ! axoneme +created_by: krc +creation_date: 2015-03-27T22:33:23Z + +[Term] +id: GO:1990717 +name: axonemal central bridge +namespace: cellular_component +def: "Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules." [GOC:cilia, PMID:21586547, PMID:9295136] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:1990716 ! axonemal central apparatus +created_by: krc +creation_date: 2015-03-27T22:38:31Z + +[Term] +id: GO:1990718 +name: axonemal central pair projection +namespace: cellular_component +def: "Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules." [GOC:cilia, PMID:21586547, PMID:9295136] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:1990716 ! axonemal central apparatus +created_by: krc +creation_date: 2015-03-27T22:43:01Z + +[Term] +id: GO:1990719 +name: C1 axonemal microtubule +namespace: cellular_component +def: "One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections." [GOC:cilia, PMID:21586547, PMID:9295136] +synonym: "C1 tubule" BROAD [] +is_a: GO:0005879 ! axonemal microtubule +relationship: part_of GO:0097540 ! axonemal central pair +created_by: krc +creation_date: 2015-03-27T22:55:12Z + +[Term] +id: GO:1990720 +name: C2 axonemal microtubule +namespace: cellular_component +def: "One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections." [GOC:cilia, PMID:21586547, PMID:9295136] +synonym: "C2 tubule" BROAD [] +is_a: GO:0005879 ! axonemal microtubule +relationship: part_of GO:0097540 ! axonemal central pair +created_by: krc +creation_date: 2015-03-27T22:58:40Z + +[Term] +id: GO:1990721 +name: obsolete prostatic acid phosphatase complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP." [GOC:bhm, PMID:12525165] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "ACPP homodimer complex" NARROW [] +synonym: "PAP complex" EXACT [] +synonym: "prostatic acid phosphatase complex" EXACT [] +xref: IntAct:EBI-10758257 +xref: IntAct:EBI-10758292 +is_obsolete: true +created_by: bhm +creation_date: 2015-04-01T09:43:14Z + +[Term] +id: GO:1990722 +name: DAPK1-calmodulin complex +namespace: cellular_component +def: "A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding." [GOC:bhm, PMID:20103772] +synonym: "death-associated protein kinase 1 - calmodulin complex" EXACT [] +xref: IntAct:EBI-10758257 +xref: IntAct:EBI-10758292 +is_a: GO:1902554 ! serine/threonine protein kinase complex +created_by: bhm +creation_date: 2015-04-01T13:05:17Z + +[Term] +id: GO:1990723 +name: cytoplasmic periphery of the nuclear pore complex +namespace: cellular_component +def: "Cytoplasm situated in close proximity to a nuclear pore complex." [PMID:9398662] +is_a: GO:0048471 ! perinuclear region of cytoplasm +created_by: sl +creation_date: 2015-04-06T19:26:54Z + +[Term] +id: GO:1990724 +name: galectin complex +namespace: cellular_component +def: "A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes." [GOC:bhm, PMID:15476813, PMID:18777589, PMID:8262940] +comment: An example of this is Galectin-1 in human (P09382) in PMID:15476813 (inferred from physical interaction). +synonym: "galectin-1 complex" NARROW [] +synonym: "galectin-2 complex" NARROW [] +xref: IntAct:EBI-10705755 +xref: IntAct:EBI-10705946 +xref: IntAct:EBI-10705984 +xref: IntAct:EBI-10706026 +is_a: GO:0098635 ! protein complex involved in cell-cell adhesion +created_by: bhm +creation_date: 2015-04-07T15:03:15Z + +[Term] +id: GO:1990725 +name: cord factor receptor activity +namespace: molecular_function +def: "Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity." [GOC:hjd, PMID:23602766] +synonym: "TMD receptor activity" EXACT [] +synonym: "trehalose 6,6'-dimycolate receptor activity" EXACT [] +xref: Wikipedia:Cord_factor +is_a: GO:0038023 ! signaling receptor activity +created_by: hjd +creation_date: 2015-04-07T20:53:31Z + +[Term] +id: GO:1990726 +name: Lsm1-7-Pat1 complex +namespace: cellular_component +def: "A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway." [GOC:bhm, GOC:krc, PMID:19121818, PMID:23620288, PMID:24139796, PMID:27627834, PMID:28768202] +xref: IntAct:EBI-16419327 +is_a: GO:0120114 ! Sm-like protein family complex +created_by: pr +creation_date: 2015-04-08T09:22:36Z + +[Term] +id: GO:1990727 +name: tubulin folding cofactor complex +namespace: cellular_component +def: "A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur." [GOC:vw, PMID:12445400] +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2015-04-08T10:29:43Z + +[Term] +id: GO:1990728 +name: mitotic spindle assembly checkpoint MAD1-MAD2 complex +namespace: cellular_component +def: "A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex." [GOC:bhm, PMID:12006501, PMID:22898774] +comment: An example of this is MAD1 in human (Q9Y6D9) in PMID:12006501 (inferred from physical interaction). +synonym: "MAD1-MAD2 complex" EXACT [] +xref: IntAct:EBI-10691260 +xref: IntAct:EBI-10705307 +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990706 ! MAD1 complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bhm +creation_date: 2015-04-15T10:14:17Z + +[Term] +id: GO:1990729 +name: primary miRNA modification +namespace: biological_process +def: "The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically." [PMID:25799998] +is_a: GO:0009451 ! RNA modification +is_a: GO:0031053 ! primary miRNA processing +created_by: sp +creation_date: 2015-04-16T06:19:22Z + +[Term] +id: GO:1990730 +name: VCP-NSFL1C complex +namespace: cellular_component +def: "A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97." [GOC:bf, GOC:PARL, PMID:9214505] +synonym: "p97-p47 complex" EXACT [GOC:bf, PMID:12847084] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005737 ! cytoplasm +created_by: bf +creation_date: 2015-04-20T12:27:35Z + +[Term] +id: GO:1990731 +name: UV-damage excision repair, DNA incision +namespace: biological_process +def: "A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)." [PMID:10704216] +synonym: "alternative excision repair, DNA incision" RELATED [PMID:10704216] +synonym: "DNA incision involved in AER" RELATED [PMID:10704216] +synonym: "DNA incision involved in alternative excision repair" RELATED [PMID:10704216] +synonym: "DNA incision involved in UV-damage excision repair" EXACT [] +synonym: "DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair" EXACT [] +synonym: "DNA incision involved in UVDE-dependent excision repair" EXACT [] +synonym: "DNA incision involved in UVER" EXACT [] +synonym: "nucleic acid cleavage involved in UV-damage excision repair" EXACT [] +synonym: "UV-damaged DNA endonuclease-dependent excision repair, DNA incision" EXACT [] +synonym: "UVDE-dependent excision repair, DNA incision" EXACT [] +is_a: GO:0090305 ! nucleic acid phosphodiester bond hydrolysis +relationship: part_of GO:0070914 ! UV-damage excision repair +created_by: mah +creation_date: 2015-04-21T15:09:04Z + +[Term] +id: GO:1990732 +name: pyrenoid +namespace: cellular_component +def: "A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation." [GOC:cjm, GOC:pr, PMID:23345319, Wikipedia:Pyrenoid] +xref: Wikipedia:Pyrenoid +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0009536 ! plastid +created_by: pr +creation_date: 2015-04-24T12:44:52Z + +[Term] +id: GO:1990733 +name: titin-telethonin complex +namespace: cellular_component +def: "A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils." [GOC:ame, PMID:16407954] +comment: An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay). +synonym: "Titin-Tcap complex" RELATED [] +xref: IntAct:EBI-10711453 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0030018 ! Z disc +created_by: ame +creation_date: 2015-04-24T14:57:08Z + +[Term] +id: GO:1990734 +name: astral microtubule anchoring at mitotic spindle pole body +namespace: biological_process +def: "Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end." [PMID:15004232] +is_a: GO:0034631 ! microtubule anchoring at spindle pole body +created_by: vw +creation_date: 2015-04-28T12:15:18Z + +[Term] +id: GO:1990735 +name: gamma-tubulin complex localization to mitotic spindle pole body +namespace: biological_process +def: "Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body." [GOC:dos, GOC:mah, PMID:11080156] +synonym: "establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body" EXACT [] +synonym: "gamma-tubulin complex localisation to mitotic spindle pole body" EXACT [] +synonym: "gamma-tubulin complex localization to mitotic SPB" EXACT [] +is_a: GO:0033566 ! gamma-tubulin complex localization +is_a: GO:1902440 ! protein localization to mitotic spindle pole body +created_by: mah +creation_date: 2015-04-29T14:40:20Z + +[Term] +id: GO:1990736 +name: regulation of vascular smooth muscle cell membrane depolarization +namespace: biological_process +def: "Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell." [PMID:20826763] +is_a: GO:0051899 ! membrane depolarization +created_by: sl +creation_date: 2015-04-29T22:33:19Z + +[Term] +id: GO:1990737 +name: response to manganese-induced endoplasmic reticulum stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus." [GOC:bf, GOC:PARL, PMID:23934647] +synonym: "manganese-induced ER stress response" EXACT [GOC:bf] +synonym: "response to manganese-induced ER stress" EXACT [GOC:bf] +synonym: "response to Mn-induced ER stress" EXACT [PMID:23934647] +is_a: GO:0034976 ! response to endoplasmic reticulum stress +is_a: GO:0062197 ! cellular response to chemical stress +is_a: GO:0071287 ! cellular response to manganese ion +created_by: bf +creation_date: 2015-04-30T13:48:45Z + +[Term] +id: GO:1990738 +name: pseudouridine 5'-phosphatase activity +namespace: molecular_function +def: "Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate." [EC:3.1.3.96, PMID:20722631] +xref: EC:3.1.3.96 +is_a: GO:0016791 ! phosphatase activity +created_by: vw +creation_date: 2015-05-02T11:05:50Z + +[Term] +id: GO:1990739 +name: granulosa cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge." [PMID:22383759] +is_a: GO:0050673 ! epithelial cell proliferation +created_by: sl +creation_date: 2015-05-06T18:56:04Z + +[Term] +id: GO:1990740 +name: obsolete non-selective anion channel activity +namespace: molecular_function +def: "OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient." [GOC:pr, ISBN:0878937420, Wikipedia:Ion_channel#Classification_by_type_of_ions] +comment: This term was made obsolete because it was added in error. +synonym: "nonselective anion channel activity" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2015-05-11T13:25:35Z + +[Term] +id: GO:1990741 +name: obsolete non-selective cation channel activity +namespace: molecular_function +def: "OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:pr, ISBN:0878937420, Wikipedia:Ion_channel#Classification_by_type_of_ions] +comment: This term was made obsolete because it was added in error. +synonym: "nonselective cation channel activity" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2015-05-11T13:27:15Z + +[Term] +id: GO:1990742 +name: microvesicle +namespace: cellular_component +def: "An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm." [GOC:vesicles, PMID:22418571, PMID:24009894, Wikipedia:Microvesicles] +synonym: "ectosome" EXACT [PMID:25683921] +synonym: "extracellular microvesicle" EXACT [] +synonym: "shedding vesicle" BROAD [] +is_a: GO:1903561 ! extracellular vesicle +created_by: pr +creation_date: 2015-05-13T13:44:52Z + +[Term] +id: GO:1990743 +name: protein sialylation +namespace: biological_process +def: "A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein." [PMID:21930713] +is_a: GO:0006464 ! cellular protein modification process +is_a: GO:0097503 ! sialylation +created_by: sl +creation_date: 2015-05-14T20:18:28Z + +[Term] +id: GO:1990744 +name: primary miRNA methylation +namespace: biological_process +def: "The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule." [PMID:25799998] +is_a: GO:0001510 ! RNA methylation +is_a: GO:1990729 ! primary miRNA modification +created_by: sp +creation_date: 2015-05-15T05:18:47Z + +[Term] +id: GO:1990745 +name: EARP complex +namespace: cellular_component +def: "A quatrefoil tethering complex required for endocytic recycling." [PMID:25799061] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0055037 ! recycling endosome +created_by: sp +creation_date: 2015-05-15T10:23:25Z + +[Term] +id: GO:1990747 +name: pancreatic trypsinogen secretion +namespace: biological_process +def: "The regulated release of trypsinogen from the cells of the exocrine pancreas." [PMID:12771515] +synonym: "pancreatic trypsinogen release" EXACT [] +is_a: GO:0009306 ! protein secretion +relationship: part_of GO:0030157 ! pancreatic juice secretion +created_by: sl +creation_date: 2015-05-15T17:41:25Z + +[Term] +id: GO:1990748 +name: cellular detoxification +namespace: biological_process +def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] +is_a: GO:0009987 ! cellular process +is_a: GO:0098754 ! detoxification +relationship: part_of GO:0097237 ! cellular response to toxic substance +created_by: vw +creation_date: 2015-05-18T16:17:46Z + +[Term] +id: GO:1990749 +name: polynucleotide adenylyltransferase activator activity +namespace: molecular_function +def: "Increases the activity of the enzyme polynucleotide adenylyltransferase." [GOC:kmv, PMID:19460348] +is_a: GO:0008047 ! enzyme activator activity +created_by: kmv +creation_date: 2015-05-19T15:02:39Z + +[Term] +id: GO:1990750 +name: obsolete axon shaft +namespace: cellular_component +def: "OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites." [PMID:11264310, PMID:24312009] +comment: This term was made obsolete because it was added in error. +synonym: "axonal shaft" EXACT [] +is_obsolete: true +consider: GO:0044304 +created_by: sl +creation_date: 2015-05-21T17:46:18Z + +[Term] +id: GO:1990751 +name: Schwann cell chemotaxis +namespace: biological_process +def: "The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [PMID:16203995] +is_a: GO:0036135 ! Schwann cell migration +is_a: GO:0060326 ! cell chemotaxis +created_by: sl +creation_date: 2015-05-21T19:19:09Z + +[Term] +id: GO:1990752 +name: microtubule end +namespace: cellular_component +def: "Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end." [GOC:pr] +comment: This term should be used when it is not possible to distinguish between the two microtubule ends, e.g. during image annotation. Whenever possible, please annotate to one of the more specific children GO:0035371 'microtubule plus-end' or GO:0036449 'microtubule minus-end'. +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005874 ! microtubule +created_by: pr +creation_date: 2015-05-25T12:50:31Z + +[Term] +id: GO:1990753 +name: equatorial cell cortex +namespace: cellular_component +def: "The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression." [GOC:kmv, PMID:16352658, PMID:22552143, PMID:23750214, PMID:25898168] +is_a: GO:0099738 ! cell cortex region +relationship: part_of GO:0032153 ! cell division site +created_by: kmv +creation_date: 2015-05-27T19:12:41Z + +[Term] +id: GO:1990754 +name: obsolete GABAergic neuronal action potential +namespace: biological_process +def: "OBSOLETE. An action potential that occurs in a GABAergic neuron." [PMID:16921370] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "GABAergic neuronal action potential" EXACT [] +is_obsolete: true +created_by: pg +creation_date: 2015-05-28T08:58:42Z + +[Term] +id: GO:1990755 +name: mitotic spindle microtubule depolymerization +namespace: biological_process +def: "The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle." [PMID:25253718] +synonym: "mitotic spindle microtubule depolymerisation" EXACT [] +is_a: GO:0007019 ! microtubule depolymerization +created_by: mah +creation_date: 2015-05-28T15:42:06Z + +[Term] +id: GO:1990756 +name: ubiquitin ligase-substrate adaptor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins." [PMID:24658274] +synonym: "protein binding, bridging involved in substrate recognition for ubiquitination" EXACT [] +synonym: "ubiquitin ligase substrate adaptor" EXACT [] +is_a: GO:0030674 ! protein-macromolecule adaptor activity +intersection_of: GO:0030674 ! protein-macromolecule adaptor activity +intersection_of: part_of GO:0016567 ! protein ubiquitination +relationship: part_of GO:0016567 ! protein ubiquitination +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/18655 xsd:anyURI +created_by: vw +creation_date: 2015-06-01T08:35:16Z + +[Term] +id: GO:1990757 +name: ubiquitin ligase activator activity +namespace: molecular_function +alt_id: GO:0061636 +def: "Binds to and increases the activity of a ubiquitin ligase." [GOC:dph, PMID:25619242] +synonym: "mitotic anaphase-promoting complex activator activity" NARROW [] +is_a: GO:0097027 ! ubiquitin-protein transferase activator activity +relationship: part_of GO:1904668 ! positive regulation of ubiquitin protein ligase activity +created_by: vw +creation_date: 2015-06-01T08:53:04Z + +[Term] +id: GO:1990758 +name: mitotic sister chromatid biorientation +namespace: biological_process +def: "The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression." [PMID:15309047, PMID:26258632, PMID:26705896] +is_a: GO:0031134 ! sister chromatid biorientation +is_a: GO:0051315 ! attachment of mitotic spindle microtubules to kinetochore +intersection_of: GO:0031134 ! sister chromatid biorientation +intersection_of: part_of GO:0000278 ! mitotic cell cycle +relationship: has_part GO:0051010 ! microtubule plus-end binding +created_by: vw +creation_date: 2015-06-02T12:36:17Z + +[Term] +id: GO:1990760 +name: osmolarity-sensing cation channel activity +namespace: molecular_function +def: "Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides." [PMID:18279313] +is_a: GO:0005034 ! osmosensor activity +is_a: GO:0005261 ! cation channel activity +is_a: GO:0022836 ! gated channel activity +created_by: sl +creation_date: 2015-06-05T21:58:50Z + +[Term] +id: GO:1990761 +name: growth cone lamellipodium +namespace: cellular_component +def: "A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments." [GOC:dos, PMID:25598228] +is_a: GO:0030027 ! lamellipodium +is_a: GO:0043005 ! neuron projection +relationship: part_of GO:0030426 ! growth cone +created_by: sl +creation_date: 2015-06-05T22:31:19Z + +[Term] +id: GO:1990762 +name: cytoplasmic alanyl-tRNA aminoacylation +namespace: biological_process +def: "The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation." [GOC:vw] +is_a: GO:0006419 ! alanyl-tRNA aminoacylation +relationship: part_of GO:0002181 ! cytoplasmic translation +created_by: vw +creation_date: 2015-06-08T15:56:51Z + +[Term] +id: GO:1990763 +name: arrestin family protein binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors." [PMID:23911909] +is_a: GO:0005515 ! protein binding +created_by: sl +creation_date: 2015-06-09T23:29:42Z + +[Term] +id: GO:1990764 +name: myofibroblast contraction +namespace: biological_process +def: "The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast." [PMID:19239477] +synonym: "MF contraction" EXACT [] +synonym: "MFB contraction" EXACT [] +is_a: GO:0070252 ! actin-mediated cell contraction +created_by: sl +creation_date: 2015-06-09T23:43:09Z + +[Term] +id: GO:1990765 +name: colon smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253] +is_a: GO:0006939 ! smooth muscle contraction +relationship: part_of GO:0014827 ! intestine smooth muscle contraction +created_by: sl +creation_date: 2015-06-10T18:29:21Z + +[Term] +id: GO:1990767 +name: prostaglandin receptor internalization +namespace: biological_process +def: "The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle." [PMID:15937517] +is_a: GO:0002031 ! G protein-coupled receptor internalization +created_by: sl +creation_date: 2015-06-10T19:14:08Z + +[Term] +id: GO:1990768 +name: gastric mucosal blood circulation +namespace: biological_process +def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413] +synonym: "stomach mucosal blood circulation" EXACT [] +is_a: GO:0008015 ! blood circulation +created_by: sl +creation_date: 2015-06-10T20:11:09Z + +[Term] +id: GO:1990769 +name: proximal neuron projection +namespace: cellular_component +def: "The portion of an axon or dendrite that is close to the neuronal cell body." [PMID:21104189] +is_a: GO:0043005 ! neuron projection +created_by: sl +creation_date: 2015-06-10T20:30:40Z + +[Term] +id: GO:1990770 +name: small intestine smooth muscle contraction +namespace: biological_process +def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626] +is_a: GO:0006939 ! smooth muscle contraction +relationship: part_of GO:0014827 ! intestine smooth muscle contraction +created_by: sl +creation_date: 2015-06-11T18:02:33Z + +[Term] +id: GO:1990771 +name: clathrin-dependent extracellular exosome endocytosis +namespace: biological_process +def: "The clathrin-mediated endocytosis of an extracellular exosome." [PMID:24951588] +synonym: "clathrin-mediated extracellular exosome endocytosis" EXACT [] +synonym: "exosome related" EXACT [] +is_a: GO:0051650 ! establishment of vesicle localization +is_a: GO:0072583 ! clathrin-dependent endocytosis +created_by: sl +creation_date: 2015-06-15T17:03:57Z + +[Term] +id: GO:1990772 +name: substance P secretion +namespace: biological_process +def: "The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity." [PMID:11278900] +is_a: GO:0030072 ! peptide hormone secretion +created_by: sl +creation_date: 2015-06-15T18:17:30Z + +[Term] +id: GO:1990773 +name: matrix metallopeptidase secretion +namespace: biological_process +def: "The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins." [PMID:8679543] +synonym: "matrix metalloproteinase secretion" NARROW [] +synonym: "MMP secretion" EXACT [] +is_a: GO:0009306 ! protein secretion +created_by: sl +creation_date: 2015-06-15T19:12:06Z + +[Term] +id: GO:1990774 +name: tumor necrosis factor secretion +namespace: biological_process +def: "The regulated release of tumor necrosis factor from a cell. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [PMID:15560120] +synonym: "cachectin secretion" EXACT [] +synonym: "TNF secretion" EXACT [] +synonym: "TNF superfamily, member 2 secretion" EXACT [] +synonym: "TNF-alpha secretion" EXACT [] +synonym: "Tnfa secretion" EXACT [] +synonym: "tumor necrosis factor alpha secretion" EXACT [] +synonym: "tumor necrosis factor ligand superfamily member 2 secretion" EXACT [] +is_a: GO:0050663 ! cytokine secretion +relationship: part_of GO:0032640 ! tumor necrosis factor production +created_by: sl +creation_date: 2015-06-15T22:59:26Z + +[Term] +id: GO:1990775 +name: endothelin secretion +namespace: biological_process +def: "The regulated release of endothelin from a cell. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions." [PMID:15560120] +synonym: "EDN1 secretion" NARROW [] +synonym: "EDN2 secretion" NARROW [] +synonym: "EDN3 secretion" NARROW [] +synonym: "endothelin-1 secretion" NARROW [] +synonym: "endothelin-2 secretion" NARROW [] +synonym: "endothelin-3 secretion" NARROW [] +is_a: GO:0050663 ! cytokine secretion +created_by: sl +creation_date: 2015-06-15T23:13:18Z + +[Term] +id: GO:1990776 +name: response to angiotensin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen." [PMID:22982863] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-06-16T17:41:17Z + +[Term] +id: GO:1990777 +name: lipoprotein particle +namespace: cellular_component +def: "A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph." [GOC:vesicles] +is_a: GO:0032994 ! protein-lipid complex +created_by: pr +creation_date: 2015-06-18T08:42:53Z + +[Term] +id: GO:1990778 +name: protein localization to cell periphery +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290] +is_a: GO:0034613 ! cellular protein localization +creation_date: 2015-06-18T22:37:39Z + +[Term] +id: GO:1990779 +name: glycoprotein Ib-IX-V complex +namespace: cellular_component +def: "A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation." [GOC:bhm, PMID:1730602, PMID:23336709, PMID:25297919] +comment: An example of this is GB1BA in human (P07359) in PMID:1730602 (inferred from direct assay). +synonym: "CD42" EXACT [] +synonym: "GPIb-IX-V complex" EXACT [] +synonym: "GPIb-V-IX complex" EXACT [] +xref: IntAct:EBI-10727454 +xref: IntAct:EBI-10728062 +is_a: GO:0090665 ! glycoprotein complex +is_a: GO:0098802 ! plasma membrane signaling receptor complex +relationship: part_of GO:0005887 ! integral component of plasma membrane +created_by: bhm +creation_date: 2015-06-23T11:22:12Z + +[Term] +id: GO:1990780 +name: cytoplasmic side of dendritic spine plasma membrane +namespace: cellular_component +def: "The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine." [PMID:9275233] +is_a: GO:0009898 ! cytoplasmic side of plasma membrane +relationship: part_of GO:0032591 ! dendritic spine membrane +created_by: sl +creation_date: 2015-06-23T18:35:39Z + +[Term] +id: GO:1990781 +name: response to immobilization stress combined with electrical stimulus +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile." [PMID:17008368] +is_a: GO:0035902 ! response to immobilization stress +is_a: GO:0051602 ! response to electrical stimulus +created_by: sl +creation_date: 2015-06-23T20:30:42Z + +[Term] +id: GO:1990782 +name: protein tyrosine kinase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with protein tyrosine kinase." [PMID:25499537] +synonym: "tyrosine kinase binding" EXACT [] +is_a: GO:0019901 ! protein kinase binding +created_by: sl +creation_date: 2015-06-23T20:50:58Z + +[Term] +id: GO:1990783 +name: periphagosomal region of cytoplasm +namespace: cellular_component +def: "Cytoplasm situated near, or occurring around, a phagosome." [PMID:18250451] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005737 ! cytoplasm +created_by: sl +creation_date: 2015-06-23T21:46:10Z + +[Term] +id: GO:1990784 +name: response to dsDNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus." [PMID:10051633] +synonym: "response to double-stranded DNA" EXACT [] +is_a: GO:0014070 ! response to organic cyclic compound +is_a: GO:1901698 ! response to nitrogen compound +created_by: sl +creation_date: 2015-06-24T17:54:13Z + +[Term] +id: GO:1990785 +name: response to water-immersion restraint stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile." [PMID:10882227] +synonym: "response to immobilization stress combined with water immersion" EXACT [] +is_a: GO:0035902 ! response to immobilization stress +created_by: sl +creation_date: 2015-06-24T18:27:28Z + +[Term] +id: GO:1990786 +name: cellular response to dsDNA +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus." [PMID:10051633] +is_a: GO:0071407 ! cellular response to organic cyclic compound +is_a: GO:1901699 ! cellular response to nitrogen compound +is_a: GO:1990784 ! response to dsDNA +created_by: sl +creation_date: 2015-06-24T22:48:25Z + +[Term] +id: GO:1990787 +name: negative regulation of hh target transcription factor activity +namespace: biological_process +def: "Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling." [GOC:bhm, PMID:24311597] +synonym: "negative regulation of hedgehog target transcription factor" EXACT [] +xref: IntAct:EBI-10170144 +is_a: GO:0045879 ! negative regulation of smoothened signaling pathway +is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity +created_by: bhm +creation_date: 2015-06-26T09:54:29Z + +[Term] +id: GO:1990788 +name: GLI-SUFU complex +namespace: cellular_component +def: "A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins." [GOC:bhm, PMID:24311597] +comment: An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay). +xref: IntAct:EBI-10170144 +xref: IntAct:EBI-10828915 +xref: IntAct:EBI-10828948 +xref: IntAct:EBI-10828976 +xref: IntAct:EBI-10828997 +xref: IntAct:EBI-10829035 +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0005829 ! cytosol +created_by: bhm +creation_date: 2015-06-26T13:49:47Z + +[Term] +id: GO:1990789 +name: thyroid gland epithelial cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population." [PMID:17646383] +synonym: "Hurthle cell proliferation" NARROW [] +synonym: "thyroid follicular cell proliferation" NARROW [] +is_a: GO:0050673 ! epithelial cell proliferation +relationship: part_of GO:0030878 ! thyroid gland development +created_by: sl +creation_date: 2015-07-02T18:50:01Z + +[Term] +id: GO:1990790 +name: response to glial cell derived neurotrophic factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus." [PMID:20877310] +synonym: "response to astrocyte-derived trophic factor" EXACT [] +synonym: "response to ATF" EXACT [] +synonym: "response to GDNF" EXACT [] +is_a: GO:0009719 ! response to endogenous stimulus +is_a: GO:0070848 ! response to growth factor +created_by: sl +creation_date: 2015-07-02T19:47:05Z + +[Term] +id: GO:1990791 +name: dorsal root ganglion development +namespace: biological_process +def: "The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure." [PMID:18583150] +synonym: "DRG development" EXACT [] +is_a: GO:0061548 ! ganglion development +created_by: sl +creation_date: 2015-07-02T22:09:54Z + +[Term] +id: GO:1990792 +name: cellular response to glial cell derived neurotrophic factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus." [PMID:20877310] +synonym: "cellular response to astrocyte-derived trophic factor" EXACT [] +synonym: "cellular response to ATF" EXACT [] +synonym: "cellular response to GDNF" EXACT [] +is_a: GO:0071363 ! cellular response to growth factor stimulus +is_a: GO:0071495 ! cellular response to endogenous stimulus +is_a: GO:1990790 ! response to glial cell derived neurotrophic factor +created_by: sl +creation_date: 2015-07-06T15:27:38Z + +[Term] +id: GO:1990793 +name: substance P secretion, neurotransmission +namespace: biological_process +def: "The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter." [PMID:15292051] +is_a: GO:0007269 ! neurotransmitter secretion +is_a: GO:1990772 ! substance P secretion +created_by: sl +creation_date: 2015-07-09T19:43:36Z + +[Term] +id: GO:1990794 +name: basolateral part of cell +namespace: cellular_component +def: "The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells." [PMID:18495799] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0045178 ! basal part of cell +relationship: part_of GO:0097574 ! lateral part of cell +created_by: sl +creation_date: 2015-07-09T20:31:50Z + +[Term] +id: GO:1990795 +name: rod bipolar cell terminal bouton +namespace: cellular_component +def: "A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer." [PMID:19883736] +is_a: GO:0043195 ! terminal bouton +created_by: sl +creation_date: 2015-07-09T21:11:53Z + +[Term] +id: GO:1990796 +name: photoreceptor cell terminal bouton +namespace: cellular_component +def: "A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light." [PMID:19883736] +is_a: GO:0043195 ! terminal bouton +created_by: sl +creation_date: 2015-07-09T21:33:40Z + +[Term] +id: GO:1990797 +name: obsolete cholecystokinin secretion +namespace: biological_process +def: "OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain." [PMID:2755938] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "CCK secretion" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2015-07-09T23:14:23Z + +[Term] +id: GO:1990798 +name: pancreas regeneration +namespace: biological_process +def: "The regrowth of a destroyed pancreas." [PMID:1985964] +is_a: GO:0031100 ! animal organ regeneration +created_by: sl +creation_date: 2015-07-10T22:53:53Z + +[Term] +id: GO:1990799 +name: mitochondrial tRNA wobble position uridine thiolation +namespace: biological_process +def: "The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps." [PMID:15509579] +is_a: GO:0002143 ! tRNA wobble position uridine thiolation +is_a: GO:0070899 ! mitochondrial tRNA wobble uridine modification +is_a: GO:0070903 ! mitochondrial tRNA thio-modification +created_by: vw +creation_date: 2015-07-13T08:15:15Z + +[Term] +id: GO:1990800 +name: obsolete meiotic APC-fizzy-related complex +namespace: cellular_component +def: "OBSOLETE. An anaphase promoting complex bound to a fizzy-related family APC activator that regulates meiotic exit by activating the APC/C to target meiotic cyclins for destruction during meiosis." [PMID:11493649] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2015-07-16T10:37:05Z + +[Term] +id: GO:1990801 +name: obsolete protein phosphorylation involved in mitotic spindle assembly +namespace: biological_process +def: "OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly." [GO_REF:0000060, GOC:rb, GOC:TermGenie, PMID:21558801] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "protein amino acid phosphorylation involved in mitotic spindle assembly" EXACT [] +synonym: "protein amino acid phosphorylation involved in spindle assembly involved in mitosis" EXACT [] +synonym: "protein phosphorylation involved in spindle assembly involved in mitosis" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14137 xsd:anyURI +is_obsolete: true +created_by: rb +creation_date: 2015-07-16T18:36:05Z + +[Term] +id: GO:1990802 +name: obsolete protein phosphorylation involved in DNA double-strand break processing +namespace: biological_process +def: "OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing." [GO_REF:0000060, GOC:rb, GOC:TermGenie, PMID:21841787] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "protein amino acid phosphorylation involved in DNA double-strand break processing" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14137 xsd:anyURI +is_obsolete: true +created_by: rb +creation_date: 2015-07-16T20:43:39Z + +[Term] +id: GO:1990803 +name: obsolete protein phosphorylation involved in protein localization to spindle microtubule +namespace: biological_process +def: "OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule." [GO_REF:0000060, GOC:rb, GOC:TermGenie, PMID:22521784] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "protein amino acid phosphorylation involved in protein localisation in spindle microtubule" EXACT [] +synonym: "protein amino acid phosphorylation involved in protein localisation to spindle microtubule" EXACT [] +synonym: "protein amino acid phosphorylation involved in protein localization in spindle microtubule" EXACT [] +synonym: "protein amino acid phosphorylation involved in protein localization to spindle microtubule" EXACT [] +synonym: "protein phosphorylation involved in protein localisation in spindle microtubule" EXACT [] +synonym: "protein phosphorylation involved in protein localisation to spindle microtubule" EXACT [] +synonym: "protein phosphorylation involved in protein localization in spindle microtubule" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14137 xsd:anyURI +is_obsolete: true +created_by: rb +creation_date: 2015-07-16T21:09:07Z + +[Term] +id: GO:1990804 +name: obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining." [GO_REF:0000060, GOC:rb, GOC:TermGenie, PMID:22563681] +comment: This term has been obsoleted because it represents a GO-CAM model. +synonym: "protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining" EXACT [] +synonym: "protein amino acid phosphorylation involved in NHEJ" EXACT [] +synonym: "protein phosphorylation involved in NHEJ" EXACT [] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/14137 xsd:anyURI +is_obsolete: true +created_by: rb +creation_date: 2015-07-16T21:54:01Z + +[Term] +id: GO:1990805 +name: central cylinder +namespace: cellular_component +def: "A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules." [GOC:kmv, PMID:2428682, PMID:26124290] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0035869 ! ciliary transition zone +created_by: kmv +creation_date: 2015-07-17T17:48:17Z + +[Term] +id: GO:1990806 +name: ligand-gated ion channel signaling pathway +namespace: biological_process +def: "A series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription." [GOC:bhm, PMID:25869137] +synonym: "ligand-gated ion channel signalling pathway" EXACT [] +is_a: GO:0007165 ! signal transduction +created_by: bhm +creation_date: 2015-07-20T12:09:56Z + +[Term] +id: GO:1990807 +name: obsolete protein N-acetyltransferase activity +namespace: molecular_function +def: "OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein." [GOC:dph] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: vw +creation_date: 2015-07-20T15:19:23Z + +[Term] +id: GO:1990808 +name: F-bar domain binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins." [PMID:20603077] +is_a: GO:0019904 ! protein domain specific binding +created_by: vw +creation_date: 2015-07-21T18:43:00Z + +[Term] +id: GO:1990809 +name: endoplasmic reticulum tubular network membrane organization +namespace: biological_process +def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane." [PMID:20434336] +is_a: GO:0061024 ! membrane organization +is_a: GO:0071786 ! endoplasmic reticulum tubular network organization +created_by: vw +creation_date: 2015-07-22T16:42:36Z + +[Term] +id: GO:1990810 +name: microtubule anchoring at mitotic spindle pole body +namespace: biological_process +def: "Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end." [PMID:17486116] +is_a: GO:0034631 ! microtubule anchoring at spindle pole body +is_a: GO:1902850 ! microtubule cytoskeleton organization involved in mitosis +relationship: part_of GO:0090307 ! mitotic spindle assembly +created_by: vw +creation_date: 2015-07-24T12:52:25Z + +[Term] +id: GO:1990811 +name: MWP complex +namespace: cellular_component +def: "A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin." [PMID:25987607, PMID:29021344] +synonym: "Msd1-Wdr8-Pkl1 complex" EXACT [GOC:vw] +is_a: GO:0032991 ! protein-containing complex +created_by: vw +creation_date: 2015-07-24T13:34:31Z + +[Term] +id: GO:1990812 +name: growth cone filopodium +namespace: cellular_component +def: "A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone." [PMID:25598228] +is_a: GO:0030175 ! filopodium +is_a: GO:0043005 ! neuron projection +relationship: part_of GO:0030426 ! growth cone +created_by: sl +creation_date: 2015-07-24T22:35:16Z + +[Term] +id: GO:1990813 +name: meiotic centromeric cohesion protection +namespace: biological_process +def: "The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions." [PMID:14730319, PMID:25533956] +synonym: "protection of centromeric cohesion during meiotic anaphase I" EXACT [] +is_a: GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +relationship: part_of GO:0045143 ! homologous chromosome segregation +created_by: vw +creation_date: 2015-07-28T16:15:31Z + +[Term] +id: GO:1990814 +name: DNA/DNA annealing activity +namespace: molecular_function +def: "A nucleic acid binding activity that brings together complementary sequences of ssDNA so that they pair by hydrogen bonds to form a double-stranded DNA." [PMID:25520186] +synonym: "DNA reannealing activity" EXACT [] +is_a: GO:0097617 ! annealing activity +created_by: vw +creation_date: 2015-07-29T12:35:03Z + +[Term] +id: GO:1990815 +name: obsolete regulation of protein localization to cell division site after cytokinesis +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in cell separation after cytokinesis." [PMID:25411334] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: vw +creation_date: 2015-07-29T14:03:34Z + +[Term] +id: GO:1990816 +name: vacuole-mitochondrion membrane contact site +namespace: cellular_component +def: "A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles." [PMID:25026035, PMID:25026036] +synonym: "vacuole and mitochondria patch" EXACT [] +synonym: "vCLAMP" EXACT [] +is_a: GO:0044232 ! organelle membrane contact site +created_by: mcc +creation_date: 2015-07-29T21:06:41Z + +[Term] +id: GO:1990817 +name: RNA adenylyltransferase activity +namespace: molecular_function +def: "Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group." [GOC:vw] +is_a: GO:0004652 ! polynucleotide adenylyltransferase activity +created_by: vw +creation_date: 2015-07-31T09:38:31Z + +[Term] +id: GO:1990818 +name: L-arginine transmembrane export from vacuole +namespace: biological_process +def: "The directed movement of L-arginine out of the vacuole, across the vacuolar membrane." [PMID:26083598] +is_a: GO:0032974 ! amino acid transmembrane export from vacuole +is_a: GO:0046618 ! drug export +is_a: GO:1903400 ! L-arginine transmembrane transport +created_by: vw +creation_date: 2015-08-06T15:06:33Z + +[Term] +id: GO:1990819 +name: actin fusion focus +namespace: cellular_component +def: "A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location." [PMID:25825517] +is_a: GO:0110165 ! cellular anatomical entity +relationship: has_part GO:0005884 ! actin filament +relationship: part_of GO:0015629 ! actin cytoskeleton +relationship: part_of GO:0043332 ! mating projection tip +created_by: al +creation_date: 2015-08-10T16:52:15Z + +[Term] +id: GO:1990820 +name: response to mitotic DNA integrity checkpoint signaling +namespace: biological_process +def: "A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling." [PMID:7548844] +synonym: "response to signal involved in mitotic DNA integrity checkpoint" EXACT [] +is_a: GO:0072402 ! response to DNA integrity checkpoint signaling +is_a: GO:0072414 ! response to mitotic cell cycle checkpoint signaling +created_by: mah +creation_date: 2015-08-14T10:25:46Z + +[Term] +id: GO:1990822 +name: basic amino acid transmembrane transport +namespace: biological_process +def: "The directed movement of basic amino acids from one side of a membrane to the other." [GOC:dph, GOC:vw] +is_a: GO:0003333 ! amino acid transmembrane transport +is_a: GO:0015802 ! basic amino acid transport +created_by: vw +creation_date: 2015-08-19T07:47:00Z + +[Term] +id: GO:1990823 +name: response to leukemia inhibitory factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus." [PMID:12801913] +synonym: "response to CDF" EXACT [] +synonym: "response to cholinergic differentiation factor" EXACT [] +synonym: "response to LIF" EXACT [] +is_a: GO:0034097 ! response to cytokine +created_by: sl +creation_date: 2015-08-19T16:44:21Z + +[Term] +id: GO:1990824 +name: obsolete magnesium-dependent protein complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex." [PMID:10220587] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-08-19T17:11:43Z + +[Term] +id: GO:1990825 +name: sequence-specific mRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif." [PMID:11886857] +is_a: GO:0003729 ! mRNA binding +created_by: sl +creation_date: 2015-08-19T17:42:50Z + +[Term] +id: GO:1990826 +name: nucleoplasmic periphery of the nuclear pore complex +namespace: cellular_component +def: "Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex." [PMID:10633080] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005654 ! nucleoplasm +created_by: sl +creation_date: 2015-08-19T18:26:26Z + +[Term] +id: GO:1990827 +name: deaminase binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3)." [PMID:9792439] +is_a: GO:0019899 ! enzyme binding +created_by: sl +creation_date: 2015-08-19T23:48:32Z + +[Term] +id: GO:1990828 +name: hepatocyte dedifferentiation +namespace: biological_process +def: "The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors." [PMID:20102719] +is_a: GO:0043697 ! cell dedifferentiation +created_by: sl +creation_date: 2015-08-20T14:14:57Z + +[Term] +id: GO:1990829 +name: C-rich single-stranded DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with C-rich, single-stranded DNA." [PMID:8127654] +synonym: "C-rich ssDNA binding" EXACT [] +is_a: GO:0003697 ! single-stranded DNA binding +created_by: sl +creation_date: 2015-08-20T16:05:12Z + +[Term] +id: GO:1990830 +name: cellular response to leukemia inhibitory factor +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus." [PMID:12801913] +synonym: "cellular response to CDF" EXACT [] +synonym: "cellular response to cholinergic differentiation factor" EXACT [] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:1990823 ! response to leukemia inhibitory factor +created_by: sl +creation_date: 2015-08-20T19:30:38Z + +[Term] +id: GO:1990831 +name: cellular response to carcinoembryonic antigen +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins." [PMID:10202129, PMID:14597422] +synonym: "cellular response to pregnancy specific glycoprotein" EXACT [] +is_a: GO:1904588 ! cellular response to glycoprotein +created_by: sl +creation_date: 2015-08-20T19:43:12Z + +[Term] +id: GO:1990832 +name: slow axonal transport +namespace: biological_process +def: "The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition." [PMID:6378920] +is_a: GO:0008088 ! axo-dendritic transport +created_by: sl +creation_date: 2015-08-21T17:27:32Z + +[Term] +id: GO:1990833 +name: clathrin-uncoating ATPase activity +namespace: molecular_function +def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP." [PMID:6146630, PMID:8363588] +is_a: GO:0016887 ! ATPase activity +relationship: part_of GO:0072318 ! clathrin coat disassembly +created_by: sl +creation_date: 2015-08-21T18:01:42Z + +[Term] +id: GO:1990834 +name: response to odorant +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell." [PMID:11268007] +is_a: GO:0042221 ! response to chemical +created_by: sl +creation_date: 2015-08-21T18:51:52Z + +[Term] +id: GO:1990835 +name: obsolete insulin-like growth factor production +namespace: biological_process +def: "OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [PMID:21993393] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "IGF production" RELATED [] +is_obsolete: true +created_by: sl +creation_date: 2015-08-24T16:30:53Z + +[Term] +id: GO:1990836 +name: lysosomal matrix +namespace: cellular_component +def: "A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome." [PMID:9395337] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0043202 ! lysosomal lumen +created_by: sl +creation_date: 2015-08-25T17:04:12Z + +[Term] +id: GO:1990837 +name: sequence-specific double-stranded DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding." [GOC:dos, GOC:sl] +synonym: "sequence-specific dsDNA binding" EXACT [] +is_a: GO:0003690 ! double-stranded DNA binding +is_a: GO:0043565 ! sequence-specific DNA binding +created_by: sl +creation_date: 2015-08-25T17:30:06Z + +[Term] +id: GO:1990838 +name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends +namespace: molecular_function +def: "Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P)." [PMID:23022480] +is_a: GO:0000175 ! 3'-5'-exoribonuclease activity +created_by: al +creation_date: 2015-08-26T10:24:51Z + +[Term] +id: GO:1990839 +name: response to endothelin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)." [PMID:16365184] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-08-27T19:37:52Z + +[Term] +id: GO:1990840 +name: response to lectin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties." [PMID:25996210, PMID:26306444] +comment: This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity. +is_a: GO:0009607 ! response to biotic stimulus +created_by: sl +creation_date: 2015-08-27T20:02:21Z + +[Term] +id: GO:1990841 +name: promoter-specific chromatin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA." [PMID:19948729] +is_a: GO:0003682 ! chromatin binding +created_by: sl +creation_date: 2015-08-28T14:48:29Z + +[Term] +id: GO:1990842 +name: obsolete response to prenatal stress +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy." [PMID:22738222] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to PNS" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2015-08-31T15:15:29Z + +[Term] +id: GO:1990843 +name: subsarcolemmal mitochondrion +namespace: cellular_component +def: "A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers." [PMID:23297307, PMID:26039174] +synonym: "SS mitochondrion" EXACT [] +synonym: "SSM" EXACT [] +is_a: GO:0005739 ! mitochondrion +created_by: sl +creation_date: 2015-08-31T16:05:14Z + +[Term] +id: GO:1990844 +name: interfibrillar mitochondrion +namespace: cellular_component +def: "A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers." [PMID:23297307, PMID:26039174] +synonym: "IFM" EXACT [] +synonym: "IMF mitochondrion" EXACT [] +synonym: "intermyofibrillar mitochondrion" EXACT [] +is_a: GO:0005739 ! mitochondrion +created_by: sl +creation_date: 2015-08-31T16:26:44Z + +[Term] +id: GO:1990845 +name: adaptive thermogenesis +namespace: biological_process +def: "The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature." [PMID:17260010, PMID:20363363] +is_a: GO:0008152 ! metabolic process +created_by: sl +creation_date: 2015-08-31T18:19:49Z + +[Term] +id: GO:1990846 +name: ribonucleoside-diphosphate reductase inhibitor activity +namespace: molecular_function +def: "Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase." [PMID:16317005] +is_a: GO:0004857 ! enzyme inhibitor activity +created_by: vw +creation_date: 2015-09-04T18:13:15Z + +[Term] +id: GO:1990847 +name: peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion +namespace: biological_process +def: "The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types." [PMID:9236781] +is_a: GO:0071833 ! peptide pheromone export involved in positive regulation of conjugation with cellular fusion +is_a: GO:0090539 ! peptide pheromone export by transmembrane transport +created_by: al +creation_date: 2015-09-08T15:23:26Z + +[Term] +id: GO:1990848 +name: obsolete Positive regulation of removal of reactive oxygen species +namespace: biological_process +def: "OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell." [PMID:24118096] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2015-09-09T11:59:57Z + +[Term] +id: GO:1990849 +name: maintenance of vacuolar location +namespace: biological_process +def: "Any process in which the vacuole is maintained in a specific location within a cell and prevented from moving elsewhere." [PMID:26283797] +synonym: "maintenance of vacuolar localization" EXACT [] +synonym: "maintenance of vacuole localization" EXACT [] +synonym: "maintenance of vacuole location" EXACT [] +is_a: GO:0051640 ! organelle localization +is_a: GO:0051657 ! maintenance of organelle location +created_by: mcc +creation_date: 2015-09-10T08:16:02Z + +[Term] +id: GO:1990850 +name: H-gal-GP complex +namespace: cellular_component +def: "A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus." [PMID:11166393] +synonym: "galactose-containing glycoprotein complex" NARROW [] +synonym: "Haemonchus galactose-containing glycoprotein complex" EXACT [] +is_a: GO:0098796 ! membrane protein complex +is_a: GO:1905368 ! peptidase complex +created_by: jl +creation_date: 2015-09-10T16:40:39Z + +[Term] +id: GO:1990851 +name: Wnt-Frizzled-LRP5/6 complex +namespace: cellular_component +def: "A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6." [GOC:bf, GOC:PARL, PMID:11448771, PMID:20093360] +comment: Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form. +synonym: "Frizzled-LRP5/6 complex" RELATED [GOC:bf] +synonym: "Fz/Wnt/LRP6 complex" NARROW [PMID:20093360] +synonym: "Wnt receptor complex" BROAD [GOC:bf] +synonym: "WNT-FZD-LRP5 complex" NARROW [PMID:23209147] +synonym: "Wnt-FZD-LRP5/6 trimeric complex" EXACT [PMID:23209147] +synonym: "WNT-FZD-LRP6 complex" NARROW [PMID:23209147] +synonym: "Wnt-induced Frizzled-LRP5/6 complex" RELATED [GOC:bf] +synonym: "Wnt.Fz.LRP ternary complex" EXACT [PMID:20093360] +is_a: GO:0098797 ! plasma membrane protein complex +created_by: bf +creation_date: 2015-09-14T15:59:54Z + +[Term] +id: GO:1990852 +name: protein transport along microtubule to spindle pole body +namespace: biological_process +def: "The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins." [PMID:25987607] +is_a: GO:0071989 ! establishment of protein localization to spindle pole body +is_a: GO:0098840 ! protein transport along microtubule +created_by: vw +creation_date: 2015-09-15T11:09:54Z + +[Term] +id: GO:1990853 +name: histone H2A SQE motif phosphorylation +namespace: biological_process +def: "The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone." [DOI:10.1038/35052000, PMID:15226425] +is_a: GO:0018105 ! peptidyl-serine phosphorylation +is_a: GO:1990164 ! histone H2A phosphorylation +created_by: al +creation_date: 2015-09-15T15:18:02Z + +[Term] +id: GO:1990854 +name: vacuole-ER tethering +namespace: biological_process +def: "The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles." [PMID:26283797] +synonym: "vacuole-endoplasmic reticulum attachment" EXACT [] +synonym: "vacuole-endoplasmic reticulum tethering" EXACT [] +synonym: "vacuole-ER attachment" EXACT [] +is_a: GO:0016043 ! cellular component organization +is_a: GO:0051685 ! maintenance of ER location +is_a: GO:0140056 ! organelle localization by membrane tethering +is_a: GO:1990849 ! maintenance of vacuolar location +created_by: mcc +creation_date: 2015-09-15T18:50:04Z + +[Term] +id: GO:1990855 +name: obsolete myo-inositol import across plasma membrane +namespace: biological_process +def: "OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane." [PMID:9560432] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2015-09-17T16:52:32Z + +[Term] +id: GO:1990856 +name: methionyl-initiator methionine tRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with methionine-initator methionine tRNA." [GOC:hjd, ISBN:9781555810733] +comment: An example of this is eukaryotic initiation factor 2 complex, which binds the methionyl-initiator methionine tRNA during ternary complex formation. The non-acylated tRNA is not bound. +is_a: GO:0000049 ! tRNA binding +created_by: hjd +creation_date: 2015-09-18T16:56:59Z + +[Term] +id: GO:1990857 +name: obsolete APC-Fzr1/Mfr1 complex +namespace: cellular_component +def: "OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family." [PMID:11493649] +comment: This term was made obsolete because it is too fine-grained for GO. +is_obsolete: true +consider: GO:0005680 +created_by: al +creation_date: 2015-09-22T13:29:11Z + +[Term] +id: GO:1990858 +name: cellular response to lectin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties." [PMID:25996210, PMID:26306444] +comment: This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity. +is_a: GO:1990840 ! response to lectin +created_by: sl +creation_date: 2015-09-24T15:34:42Z + +[Term] +id: GO:1990859 +name: cellular response to endothelin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)." [PMID:16365184] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1990839 ! response to endothelin +created_by: sl +creation_date: 2015-09-24T15:39:48Z + +[Term] +id: GO:1990860 +name: Pho85-Pho80 CDK-cyclin complex +namespace: cellular_component +def: "A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin." [GOC:rb, PMID:8108735] +is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex +created_by: rb +creation_date: 2015-09-24T17:53:50Z + +[Term] +id: GO:1990861 +name: Ubp3-Bre5 deubiquitination complex +namespace: cellular_component +def: "A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p." [GOC:rb, PMID:12778054, PMID:18391941] +synonym: "Ubp3-Bre5 ubiquitin protease complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2015-09-24T17:56:53Z + +[Term] +id: GO:1990862 +name: nuclear membrane complex Bqt3-Bqt4 +namespace: cellular_component +def: "A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4." [PMID:19948484] +is_a: GO:0098796 ! membrane protein complex +relationship: part_of GO:0005639 ! integral component of nuclear inner membrane +created_by: al +creation_date: 2015-09-25T12:14:28Z + +[Term] +id: GO:1990863 +name: acinar cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538] +synonym: "acinic cell proliferation" EXACT [] +synonym: "acinous cell proliferation" EXACT [] +is_a: GO:0050673 ! epithelial cell proliferation +created_by: sl +creation_date: 2015-09-25T14:26:09Z + +[Term] +id: GO:1990864 +name: response to growth hormone-releasing hormone +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins." [PMID:7720628] +synonym: "response to GHRF" EXACT [] +synonym: "response to GRF" EXACT [] +synonym: "response to growth hormone-releasing factor" EXACT [] +synonym: "response to sermorelin" RELATED [] +synonym: "response to somatocrinin" EXACT [] +synonym: "response to somatoliberin" EXACT [] +synonym: "response to somatorelin" EXACT [] +is_a: GO:0009725 ! response to hormone +created_by: sl +creation_date: 2015-09-25T14:45:31Z + +[Term] +id: GO:1990865 +name: obsolete response to intermittent hypoxia +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an episodic stimulus indicating lowered oxygen tension." [PMID:24055447] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-09-25T15:07:32Z + +[Term] +id: GO:1990866 +name: obsolete response to sustained hypoxia +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension." [PMID:24055447] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-09-25T15:18:11Z + +[Term] +id: GO:1990867 +name: response to gastrin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus." [PMID:10348814] +is_a: GO:0043434 ! response to peptide hormone +created_by: sl +creation_date: 2015-09-25T16:22:39Z + +[Term] +id: GO:1990868 +name: response to chemokine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus." [PMID:11113082] +is_a: GO:0034097 ! response to cytokine +created_by: sl +creation_date: 2015-09-25T16:37:00Z + +[Term] +id: GO:1990869 +name: cellular response to chemokine +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus." [PMID:11113082] +is_a: GO:0071345 ! cellular response to cytokine stimulus +is_a: GO:1990868 ! response to chemokine +created_by: sl +creation_date: 2015-09-25T16:39:55Z + +[Term] +id: GO:1990870 +name: obsolete protein fibril +namespace: cellular_component +def: "OBSOLETE. A polymer of proteins that form a fine fiber." [PMID:12764608] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-09-25T17:05:32Z + +[Term] +id: GO:1990871 +name: Vma12-Vma22 assembly complex +namespace: cellular_component +def: "A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p." [GOC:rb, PMID:9660861] +is_a: GO:0032991 ! protein-containing complex +created_by: rb +creation_date: 2015-09-28T19:03:28Z + +[Term] +id: GO:1990872 +name: obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter." [GOC:rb, PMID:19793923] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "negative regulation of sterol import by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol import by negative regulation of transcription from Pol II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter" EXACT [GOC:obol] +is_obsolete: true +created_by: rb +creation_date: 2015-09-28T21:22:23Z + +[Term] +id: GO:1990873 +name: intrinsic component of plasma membrane of cell tip +namespace: cellular_component +def: "The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip." [PMID:20624220] +is_a: GO:0031226 ! intrinsic component of plasma membrane +intersection_of: GO:0031224 ! intrinsic component of membrane +intersection_of: part_of GO:0031520 ! plasma membrane of cell tip +relationship: part_of GO:0031520 ! plasma membrane of cell tip +created_by: al +creation_date: 2015-09-29T10:06:25Z + +[Term] +id: GO:1990874 +name: vascular smooth muscle cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467] +synonym: "VSMC proliferation" EXACT [] +is_a: GO:0048659 ! smooth muscle cell proliferation +created_by: sl +creation_date: 2015-09-29T16:34:59Z + +[Term] +id: GO:1990875 +name: nucleoplasmic side of nuclear pore +namespace: cellular_component +def: "The side of the nuclear pore complex (NPC) that faces the nucleoplasm." [PMID:8422679] +synonym: "nucleoplasmic side of NPC" EXACT [] +synonym: "nucleoplasmic side of nuclear pore complex" EXACT [] +synonym: "nucleoplasmic side of nucleopore" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005643 ! nuclear pore +created_by: sl +creation_date: 2015-10-01T21:32:22Z + +[Term] +id: GO:1990876 +name: cytoplasmic side of nuclear pore +namespace: cellular_component +def: "The side of the nuclear pore complex (NPC) that faces the cytoplasm." [PMID:8422679] +synonym: "cytoplasmic side of NPC" EXACT [] +synonym: "cytoplasmic side of nuclear pore complex" EXACT [] +synonym: "cytoplasmic side of nucleopore" EXACT [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005643 ! nuclear pore +created_by: sl +creation_date: 2015-10-01T21:47:54Z + +[Term] +id: GO:1990877 +name: Lst4-Lst7 complex +namespace: cellular_component +def: "A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2." [GOC:rn, PMID:24095279, PMID:26387955] +synonym: "FLCN-FNIP1 complex" RELATED [] +synonym: "FLCN-FNIP2 complex" RELATED [] +synonym: "FNIP-Folliculin RagC/D GAP complex" RELATED [] +is_a: GO:1902773 ! GTPase activator complex +created_by: rb +creation_date: 2015-10-01T22:44:58Z + +[Term] +id: GO:1990878 +name: cellular response to gastrin +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus." [PMID:10348814] +is_a: GO:0071375 ! cellular response to peptide hormone stimulus +is_a: GO:1990867 ! response to gastrin +created_by: sl +creation_date: 2015-10-07T17:38:14Z + +[Term] +id: GO:1990879 +name: CST complex +namespace: cellular_component +def: "A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:19854130, PMID:22965356] +synonym: "Cdc13-Stn1-Ten1 complex" NARROW [GOC:nc] +synonym: "CTC1-OBFC1-TEN1 complex" NARROW [GOC:nc] +xref: IntAct:EBI-10043724 +xref: IntAct:EBI-8801830 +xref: IntAct:EBI-8801947 +is_a: GO:0000783 ! nuclear telomere cap complex +created_by: nc +creation_date: 2015-10-20T13:51:07Z + +[Term] +id: GO:1990880 +name: cellular detoxification of copper ion +namespace: biological_process +def: "Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration." [PMID:10369673] +is_a: GO:0010273 ! detoxification of copper ion +is_a: GO:1990748 ! cellular detoxification +relationship: part_of GO:0071280 ! cellular response to copper ion +created_by: al +creation_date: 2015-10-21T14:34:40Z + +[Term] +id: GO:1990881 +name: obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage." [PMID:26150418] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "down regulation of transcription from RNA polymerase II promoter in response to DNA damage" EXACT [] +synonym: "down-regulation of transcription from RNA polymerase II promoter in response to DNA damage" EXACT [] +synonym: "downregulation of transcription from RNA polymerase II promoter in response to DNA damage" EXACT [] +synonym: "inhibition of transcription from RNA polymerase II promoter in response to DNA damage" EXACT [] +is_obsolete: true +created_by: mcc +creation_date: 2015-10-28T13:02:18Z + +[Term] +id: GO:1990882 +name: rRNA acetylation +namespace: biological_process +def: "The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [PMID:25402480] +is_a: GO:0000154 ! rRNA modification +is_a: GO:1990884 ! RNA acetylation +created_by: al +creation_date: 2015-10-28T13:24:58Z + +[Term] +id: GO:1990883 +name: rRNA cytidine N-acetyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA." [PMID:25402480] +is_a: GO:0008080 ! N-acetyltransferase activity +created_by: al +creation_date: 2015-10-28T13:27:35Z + +[Term] +id: GO:1990884 +name: RNA acetylation +namespace: biological_process +def: "The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule." [PMID:25402480] +is_a: GO:0009451 ! RNA modification +created_by: mah +creation_date: 2015-10-28T16:28:08Z + +[Term] +id: GO:1990885 +name: obsolete protein serine/threonine kinase binding +namespace: molecular_function +def: "OBSOLETE. Interacting selectively and non-covalently with a protein serine/threonine kinase." [PMID:16982699] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-10-28T20:40:57Z + +[Term] +id: GO:1990887 +name: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+." [PMID:10419476] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: sl +creation_date: 2015-10-28T22:17:54Z + +[Term] +id: GO:1990888 +name: 2-polyprenyl-6-hydroxyphenol O-methyltransferase activity +namespace: molecular_function +def: "Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+." [PMID:10419476] +is_a: GO:0008171 ! O-methyltransferase activity +created_by: sl +creation_date: 2015-10-28T22:31:13Z + +[Term] +id: GO:1990889 +name: H4K20me3 modified histone binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a histone H4 in which the lysine residue at position 20 has been modified by trimethylation." [PMID:22150589] +is_a: GO:0035064 ! methylated histone binding +created_by: al +creation_date: 2015-10-30T15:43:09Z + +[Term] +id: GO:1990890 +name: netrin receptor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a netrin receptor." [GOC:kmv, PMID:8861902, PMID:9126742] +is_a: GO:0005102 ! signaling receptor binding +relationship: part_of GO:0038007 ! netrin-activated signaling pathway +created_by: kmv +creation_date: 2015-11-02T22:56:07Z + +[Term] +id: GO:1990891 +name: mitotic sister chromatid arm separation +namespace: biological_process +def: "The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis." [PMID:21633354] +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0051306 ! mitotic sister chromatid separation +created_by: mah +creation_date: 2015-11-03T14:01:16Z + +[Term] +id: GO:1990892 +name: mitotic chromosome arm condensation +namespace: biological_process +def: "The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [PMID:21633354] +is_a: GO:0007076 ! mitotic chromosome condensation +created_by: vw +creation_date: 2015-11-03T14:16:59Z + +[Term] +id: GO:1990893 +name: mitotic chromosome centromere condensation +namespace: biological_process +def: "The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis." [PMID:21633354] +synonym: "mitotic chromosome condensation at kinetochore" EXACT [] +is_a: GO:0007076 ! mitotic chromosome condensation +created_by: vw +creation_date: 2015-11-03T14:26:29Z + +[Term] +id: GO:1990894 +name: obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion." [PMID:22144909] +comment: This term was obsoleted during the TG review process. It should have been created using a template. +is_obsolete: true +created_by: al +creation_date: 2015-11-04T20:25:21Z + +[Term] +id: GO:1990895 +name: regulation of protein localization to cell cortex of cell tip +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip." [PMID:26150232\,GOC\:vw] +is_a: GO:1903066 ! regulation of protein localization to cell tip +is_a: GO:1904776 ! regulation of protein localization to cell cortex +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1990896 ! protein localization to cell cortex of cell tip +relationship: regulates GO:1990896 ! protein localization to cell cortex of cell tip +created_by: vw +creation_date: 2015-11-04T21:53:15Z + +[Term] +id: GO:1990896 +name: protein localization to cell cortex of cell tip +namespace: biological_process +def: "A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip." [PMID:26150232] +is_a: GO:0072697 ! protein localization to cell cortex +is_a: GO:1990151 ! protein localization to cell tip +created_by: vw +creation_date: 2015-11-05T08:41:49Z + +[Term] +id: GO:1990897 +name: obsolete CTDK-1 complex +namespace: cellular_component +def: "OBSOLETE. A protein complex that phosphorylates serine 2 residues in the CTD domain of productively elongating large subunits of DNA-directed RNA polymerase II, holoenzyme. In S. cerevisiae this complex consists of CTK1/CTK2/CTK3, in S. pombe Lsk1/Lsc1/Lsg1. Human CTK1 homologs include CDK12/13." [PMID:20952539, PMID:24879308] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2015-11-06T01:57:32Z + +[Term] +id: GO:1990898 +name: meiotic DNA double-strand break clipping +namespace: biological_process +def: "The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP)." [PMID:26130711] +is_a: GO:0044260 ! cellular macromolecule metabolic process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0010705 ! meiotic DNA double-strand break processing involved in reciprocal meiotic recombination +created_by: al +creation_date: 2015-11-10T17:12:27Z + +[Term] +id: GO:1990899 +name: meiotic DNA double-strand break resectioning +namespace: biological_process +def: "The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends." [PMID:26130711] +is_a: GO:0044260 ! cellular macromolecule metabolic process +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0010705 ! meiotic DNA double-strand break processing involved in reciprocal meiotic recombination +created_by: al +creation_date: 2015-11-10T17:23:07Z + +[Term] +id: GO:1990900 +name: ciliary pocket collar +namespace: cellular_component +def: "A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma." [GOC:giardia, PMID:18462016, PMID:19806154] +comment: Note that a 'flagellar collar' is described in Choanoflagellates, but this is different from the ciliary pocket collar found e.g. in Giardia; in Choanoflagellates, a single apical flagellum is surrounded by a collar of 30-40 microvilli. +synonym: "cilium pocket collar" EXACT [] +synonym: "flagellar collar" RELATED [] +synonym: "flagellar pocket collar" EXACT [] +synonym: "flagellar pore" RELATED [] +synonym: "flagellum pocket collar" EXACT [] +synonym: "FPC" RELATED [] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0020016 ! ciliary pocket +created_by: pr +creation_date: 2015-11-17T14:43:55Z + +[Term] +id: GO:1990901 +name: old cell pole +namespace: cellular_component +def: "The cell pole distal from the most recent cell division." [GOC:jh2, PMID:10231492, PMID:8226658] +is_a: GO:0060187 ! cell pole +created_by: pr +creation_date: 2015-11-17T16:42:16Z + +[Term] +id: GO:1990902 +name: new cell pole +namespace: cellular_component +def: "The cell pole proximal to the most recent cell division." [GOC:jh2, PMID:10231492, PMID:8226658] +is_a: GO:0060187 ! cell pole +created_by: pr +creation_date: 2015-11-17T16:44:53Z + +[Term] +id: GO:1990904 +name: ribonucleoprotein complex +namespace: cellular_component +alt_id: GO:0030529 +alt_id: GO:1990903 +def: "A macromolecular complex containing both protein and RNA molecules." [GOC:vesicles] +subset: goslim_pir +synonym: "extracellular ribonucleoprotein complex" NARROW [] +synonym: "intracellular ribonucleoprotein complex" NARROW [] +synonym: "protein-RNA complex" EXACT [] +synonym: "ribonucleoprotein complex" EXACT [] +synonym: "RNA-protein complex" EXACT [] +synonym: "RNP" EXACT [] +xref: Wikipedia:Ribonucleoprotein +is_a: GO:0032991 ! protein-containing complex +created_by: pr +creation_date: 2015-11-19T12:26:37Z + +[Term] +id: GO:1990905 +name: dinoflagellate peduncle +namespace: cellular_component +def: "A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy)." [GOC:at, PMID:1480107, Wikipedia:Dinoflagellate] +comment: The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. +is_a: GO:0120025 ! plasma membrane bounded cell projection +created_by: pr +creation_date: 2015-11-22T10:22:46Z + +[Term] +id: GO:1990906 +name: accessory outer segment +namespace: cellular_component +def: "A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors." [GOC:dph, PMID:25125189] +is_a: GO:0043005 ! neuron projection +created_by: dph +creation_date: 2015-11-24T13:56:06Z + +[Term] +id: GO:1990907 +name: beta-catenin-TCF complex +namespace: cellular_component +def: "A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors." [GOC:bf, GOC:PARL, PMID:11751639, PMID:16936075, PMID:20123964, PMID:21075118, PMID:9419974] +synonym: "beta-catenin/LEF complex" NARROW [PMID:8757136] +synonym: "beta-catenin/lymphoid enhancer binding factor complex" RELATED [PMID:8757136] +synonym: "beta-catenin/T-cell factor complex" RELATED [GOC:bf] +xref: IntAct:EBI-11424678 +xref: IntAct:EBI-11425837 +is_a: GO:0090575 ! RNA polymerase II transcription regulator complex +created_by: bf +creation_date: 2015-12-01T16:32:44Z + +[Term] +id: GO:1990908 +name: obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity +namespace: molecular_function +def: "OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile." [PMID:26368668] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2015-12-03T14:25:04Z + +[Term] +id: GO:1990909 +name: Wnt signalosome +namespace: cellular_component +def: "A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein." [GOC:bf, GOC:PARL, PMID:22899650, PMID:25336320] +comment: Within the Wnt signalosome, beta-catenin phosphorylation is inhibited through internalization of the signalosome complex, resulting in the sequestration of GSK3-beta into multi-vesicular bodies. No longer phosphorylated and targeted for degradation, beta-catenin is free to enter the nucleus and modulate downstream transcription. +synonym: "LRP5/6 signalosome" EXACT [GOC:bf] +synonym: "LRP6 signalosome" NARROW [PMID:22899650, PMID:25074807] +synonym: "Wnt signalosome complex" EXACT [PMID:24412065] +synonym: "Wnt-LRP5/6 signalosome" EXACT [PMID:23892894] +is_a: GO:0032991 ! protein-containing complex +relationship: has_part GO:1990851 ! Wnt-Frizzled-LRP5/6 complex +created_by: bf +creation_date: 2015-12-07T14:04:23Z + +[Term] +id: GO:1990910 +name: response to hypobaric hypoxia +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level)." [PMID:24590457] +is_a: GO:0001666 ! response to hypoxia +created_by: sl +creation_date: 2015-12-07T19:34:14Z + +[Term] +id: GO:1990911 +name: response to psychosocial stress +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism." [PMID:22922217, PMID:26458179] +is_a: GO:0006950 ! response to stress +created_by: sl +creation_date: 2015-12-07T20:38:35Z + +[Term] +id: GO:1990912 +name: obsolete response to microwave radiation +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microwave radiation stimulus." [PMID:21241601] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2015-12-07T21:25:08Z + +[Term] +id: GO:1990913 +name: sperm head plasma membrane +namespace: cellular_component +def: "The plasma membrane that is part of the head section of a sperm cell." [PMID:24478030] +is_a: GO:0098590 ! plasma membrane region +intersection_of: GO:0098590 ! plasma membrane region +intersection_of: part_of GO:0061827 ! sperm head +relationship: part_of GO:0061827 ! sperm head +relationship: part_of GO:0097524 ! sperm plasma membrane +created_by: sl +creation_date: 2015-12-07T23:14:04Z + +[Term] +id: GO:1990914 +name: integral component of periplasmic side of plasma membrane +namespace: cellular_component +def: "The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane." [GOC:bhm, PMID:15919996] +comment: An example of this is hyaA in E. coli (P69739) in PMID:23260654 (inferred from direct assay). +xref: IntAct:EBI-11297444 +is_a: GO:0031237 ! intrinsic component of periplasmic side of plasma membrane +is_a: GO:0071575 ! integral component of external side of plasma membrane +intersection_of: GO:0005887 ! integral component of plasma membrane +intersection_of: part_of GO:0098567 ! periplasmic side of plasma membrane +created_by: bhm +creation_date: 2015-12-09T14:38:57Z + +[Term] +id: GO:1990915 +name: structural constituent of ascospore wall +namespace: molecular_function +def: "The action of a molecule that contributes to the structural integrity of an ascospore wall." [PMID:24623719] +is_a: GO:0005199 ! structural constituent of cell wall +intersection_of: GO:0005198 ! structural molecule activity +intersection_of: occurs_in GO:0005619 ! ascospore wall +relationship: occurs_in GO:0005619 ! ascospore wall +created_by: al +creation_date: 2015-12-09T19:04:53Z + +[Term] +id: GO:1990916 +name: Isp3 layer of spore wall +namespace: cellular_component +def: "The outermost layers of the spore wall, as described in Schizosaccharomyces pombe." [PMID:24623719] +is_a: GO:0110165 ! cellular anatomical entity +relationship: part_of GO:0005619 ! ascospore wall +created_by: al +creation_date: 2015-12-09T19:07:23Z + +[Term] +id: GO:1990917 +name: ooplasm +namespace: cellular_component +def: "The cytoplasm of an ovum." [PMID:19022436] +is_a: GO:0005737 ! cytoplasm +property_value: RO:0002161 NCBITaxon:4751 +created_by: sl +creation_date: 2015-12-10T21:40:16Z + +[Term] +id: GO:1990918 +name: double-strand break repair involved in meiotic recombination +namespace: biological_process +def: "The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination." [GOC:mah, PMID:15238514] +is_a: GO:0006302 ! double-strand break repair +is_a: GO:1903046 ! meiotic cell cycle process +relationship: part_of GO:0007131 ! reciprocal meiotic recombination +created_by: al +creation_date: 2015-12-11T01:01:14Z + +[Term] +id: GO:1990919 +name: proteasome-nuclear membrane anchor activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome." [PMID:16096059] +synonym: "nuclear membrane proteasome adaptor" RELATED [] +synonym: "nuclear membrane proteasome anchor" EXACT [] +synonym: "nuclear membrane-proteasome anchor activity" EXACT [] +synonym: "tethering factor for nuclear proteasome" RELATED [] +is_a: GO:0043495 ! protein-membrane adaptor activity +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19119 xsd:anyURI +created_by: vw +creation_date: 2015-12-14T14:01:45Z + +[Term] +id: GO:1990920 +name: proteasome localization to nuclear periphery +namespace: biological_process +def: "Any process in which the proteasome is transported to, or maintained at the nuclear periphery." [PMID:11084332] +is_a: GO:0031144 ! proteasome localization +is_a: GO:1990139 ! protein localization to nuclear periphery +created_by: vw +creation_date: 2015-12-14T17:14:00Z + +[Term] +id: GO:1990921 +name: obsolete proteasome localization to nuclear periphery +namespace: biological_process +def: "OBSOLETE. A process in which a proteasome is transported to, or maintained in, a location within the nuclear periphery." [PMID:16096059] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "proteasome localisation to nuclear periphery" EXACT [] +is_obsolete: true +created_by: mah +creation_date: 2015-12-15T12:02:31Z + +[Term] +id: GO:1990922 +name: hepatic stellate cell proliferation +namespace: biological_process +def: "The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver." [GOC:sl, PMID:15358192, PMID:18466260] +synonym: "hepatic perisinusoidal cell proliferation" EXACT [] +synonym: "Ito cell proliferation" EXACT [] +synonym: "perisinusoidal cell proliferation" EXACT [] +is_a: GO:0048144 ! fibroblast proliferation +created_by: sl +creation_date: 2016-01-13T23:12:57Z + +[Term] +id: GO:1990923 +name: PET complex +namespace: cellular_component +def: "A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs." [PMID:26669262] +is_a: GO:0032991 ! protein-containing complex +created_by: sp +creation_date: 2016-01-14T02:19:39Z + +[Term] +id: GO:1990924 +name: obsolete amphisome membrane +namespace: cellular_component +def: "OBSOLETE. The lipid bilayer surrounding the amphisome and separating its contents from the cell cytoplasm." [GOC:bhm, PMID:17984323] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "amphisomal membrane" EXACT [] +is_obsolete: true +created_by: bhm +creation_date: 2016-01-27T13:58:16Z + +[Term] +id: GO:1990926 +name: short-term synaptic potentiation +namespace: biological_process +def: "The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds." [GOC:dos, GOC:sp, ISBN:9780071120005, PMID:11826273, PMID:26738595] +comment: The mechanism of short term potentiation is thought to be either increased influx of calcium into the presynapse (Zucker and Regeh, 2002 PMID:11826273) increased sensitivity to calcium (Jackman et al., 2016 PMID:26738595) or both. +synonym: "synaptic facilitation" EXACT [ISBN:9780071120005, PMID:11826273, PMID:26738595] +is_a: GO:0048167 ! regulation of synaptic plasticity +created_by: sp +creation_date: 2016-02-12T13:17:18Z + +[Term] +id: GO:1990927 +name: calcium ion regulated lysosome exocytosis +namespace: biological_process +def: "The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels." [PMID:10725327, PMID:11511344] +is_a: GO:0017156 ! calcium-ion regulated exocytosis +created_by: sp +creation_date: 2016-02-16T14:19:44Z + +[Term] +id: GO:1990928 +name: response to amino acid starvation +namespace: biological_process +def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids." [PMID:7765311] +is_a: GO:0042594 ! response to starvation +created_by: sl +creation_date: 2016-02-18T00:18:23Z + +[Term] +id: GO:1990929 +name: sulfoquinovosidase activity +namespace: molecular_function +def: "Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose." [GOC:imk, PMID:26878550] +is_a: GO:0016798 ! hydrolase activity, acting on glycosyl bonds +created_by: tb +creation_date: 2016-02-19T01:18:37Z + +[Term] +id: GO:1990930 +name: RNA N1-methyladenosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde." [PMID:26863196, PMID:26863410] +is_a: GO:0035515 ! oxidative RNA demethylase activity +created_by: sp +creation_date: 2016-03-10T08:06:47Z + +[Term] +id: GO:1990931 +name: RNA N6-methyladenosine dioxygenase activity +namespace: molecular_function +def: "Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde." [PMID:22002720, PMID:26458103] +is_a: GO:0035515 ! oxidative RNA demethylase activity +created_by: sp +creation_date: 2016-03-10T08:10:10Z + +[Term] +id: GO:1990932 +name: 5.8S rRNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA." [PMID:11716358, PMID:15527424] +is_a: GO:0019843 ! rRNA binding +created_by: sl +creation_date: 2016-03-14T20:25:41Z + +[Term] +id: GO:1990933 +name: microtubule cytoskeleton attachment to nuclear envelope +namespace: biological_process +def: "A process in which the microtubule cytoskeleton is attached to the nuclear envelope." [PMID:14655046, PMID:20507227] +is_a: GO:0007010 ! cytoskeleton organization +created_by: vw +creation_date: 2016-03-17T08:32:37Z + +[Term] +id: GO:1990934 +name: nucleolus-like body +namespace: cellular_component +def: "A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles." [PMID:26226217, PMID:9021878] +synonym: "compact nucleolus" EXACT [] +synonym: "NLB" EXACT [] +synonym: "nucleolus-like body" EXACT [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +relationship: part_of GO:0031981 ! nuclear lumen +created_by: sl +creation_date: 2016-03-21T21:28:14Z + +[Term] +id: GO:1990935 +name: splicing factor binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with any protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA." [PMID:11118435] +is_a: GO:0005515 ! protein binding +created_by: sl +creation_date: 2016-03-21T21:57:20Z + +[Term] +id: GO:1990936 +name: vascular smooth muscle cell dedifferentiation +namespace: biological_process +def: "The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:19088079] +is_a: GO:0090678 ! cell dedifferentiation involved in phenotypic switching +created_by: tb +creation_date: 2016-03-22T20:25:11Z + +[Term] +id: GO:1990937 +name: xylan acetylation +namespace: biological_process +def: "The addition of one or more acetyl groups to a xylan molecule." [PMID:26745802] +is_a: GO:0043412 ! macromolecule modification +is_a: GO:0045491 ! xylan metabolic process +created_by: tb +creation_date: 2016-03-30T22:10:22Z + +[Term] +id: GO:1990938 +name: peptidyl-aspartic acid autophosphorylation +namespace: biological_process +def: "The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein." [GOC:bf, GOC:PARL, PMID:26134396] +synonym: "aspartyl autophosphorylation" EXACT [PMID:26134396] +synonym: "peptidyl-aspartate autophosphorylation" EXACT [GOC:bf] +is_a: GO:0018217 ! peptidyl-aspartic acid phosphorylation +is_a: GO:0046777 ! protein autophosphorylation +created_by: bf +creation_date: 2016-04-04T10:49:53Z + +[Term] +id: GO:1990939 +name: ATP-dependent microtubule motor activity +namespace: molecular_function +def: "Catalysis of movement along a microtubule, coupled to the hydrolysis of ATP." [PMID:19686686] +xref: Reactome:R-HSA-9610627 "KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane" +is_a: GO:0003777 ! microtubule motor activity +is_a: GO:0016887 ! ATPase activity +created_by: vw +creation_date: 2016-04-04T10:59:42Z + +[Term] +id: GO:1990940 +name: obsolete microtubule sliding involved in mitotic spindle elongation +namespace: biological_process +def: "OBSOLETE. The movement of one microtubule along another microtubule involved in mitotic spindle elongation." [PMID:19686686] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: vw +creation_date: 2016-04-04T11:06:41Z + +[Term] +id: GO:1990941 +name: mitotic spindle kinetochore microtubule +namespace: cellular_component +def: "Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation." [PMID:18256284] +is_a: GO:0005828 ! kinetochore microtubule +is_a: GO:1990498 ! mitotic spindle microtubule +created_by: vw +creation_date: 2016-04-06T13:31:38Z + +[Term] +id: GO:1990942 +name: mitotic metaphase chromosome recapture +namespace: biological_process +def: "A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate." [PMID:18256284] +synonym: "kinetochore retrieval" EXACT [] +synonym: "metaphase chromosome retrieval to the spindle pole body" EXACT [] +synonym: "sister kinetochore recapture" EXACT [] +is_a: GO:0051303 ! establishment of chromosome localization +is_a: GO:1903047 ! mitotic cell cycle process +relationship: part_of GO:0007080 ! mitotic metaphase plate congression +created_by: vw +creation_date: 2016-04-06T14:41:56Z + +[Term] +id: GO:1990943 +name: mating type region replication fork barrier binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with the replication fork barrier found in the mating type region of fission yeast." [PMID:18723894] +synonym: "RTS1 barrier binding" EXACT [] +synonym: "RTS1 element binding" EXACT [] +is_a: GO:0031634 ! replication fork barrier binding +created_by: mah +creation_date: 2016-04-06T16:08:43Z + +[Term] +id: GO:1990946 +name: meiosis I/meiosis II transition +namespace: biological_process +def: "The cell cycle process in which a cell progresses from meiosis I to meiosis II." [PMID:21389117] +is_a: GO:0044771 ! meiotic cell cycle phase transition +created_by: vw +creation_date: 2016-04-21T13:01:07Z + +[Term] +id: GO:1990947 +name: exit from meiosis +namespace: biological_process +def: "Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half." [PMID:21389117] +synonym: "meiotic exit" EXACT [GOC:dph] +is_a: GO:0044771 ! meiotic cell cycle phase transition +created_by: vw +creation_date: 2016-04-21T14:14:15Z + +[Term] +id: GO:1990948 +name: ubiquitin ligase inhibitor activity +namespace: molecular_function +alt_id: GO:0061637 +alt_id: GO:0090645 +def: "Stops, prevents or reduces the activity of a ubiquitin ligase." [GOC:dph, GOC:vw, PMID:21389117] +synonym: "APC-Cdc20 complex inhibitor activity" NARROW [] +synonym: "mitotic anaphase-promoting complex inhibitor activity" NARROW [] +is_a: GO:0055105 ! ubiquitin-protein transferase inhibitor activity +relationship: part_of GO:1904667 ! negative regulation of ubiquitin protein ligase activity +created_by: vw +creation_date: 2016-04-21T16:36:54Z + +[Term] +id: GO:1990949 +name: metaphase/anaphase transition of meiosis I +namespace: biological_process +def: "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I." [ISBN:0815316194] +synonym: "first meiotic metaphase/anaphase transition" RELATED [] +synonym: "meiosis I metaphase/anaphase transition" EXACT [] +is_a: GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +is_a: GO:0061982 ! meiosis I cell cycle process +created_by: mah +creation_date: 2016-04-25T15:27:32Z + +[Term] +id: GO:1990950 +name: metaphase/anaphase transition of meiosis II +namespace: biological_process +def: "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II." [ISBN:0815316194] +synonym: "meiosis II metaphase/anaphase transition" EXACT [] +synonym: "second meiotic metaphase/anaphase transition" RELATED [] +is_a: GO:0044785 ! metaphase/anaphase transition of meiotic cell cycle +is_a: GO:0061983 ! meiosis II cell cycle process +created_by: mah +creation_date: 2016-04-25T15:28:51Z + +[Term] +id: GO:1990951 +name: obsolete manchette assembly +namespace: biological_process +def: "OBSOLETE. The assembly and organization of the manchette, a tubular array of microtubules, possibly also containing actin filaments, that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme." [GOC:krc, PMID:22319670, PMID:24440897, PMID:26792866] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: krc +creation_date: 2016-05-11T00:05:35Z + +[Term] +id: GO:1990952 +name: obsolete manchette disassembly +namespace: biological_process +def: "OBSOLETE. A cellular process that results in the breakdown of a manchette." [GOC:krc, PMID:22319670, PMID:24440897, PMID:26792866] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "manchette clearance" EXACT [] +is_obsolete: true +created_by: krc +creation_date: 2016-05-11T00:14:16Z + +[Term] +id: GO:1990953 +name: intramanchette transport +namespace: biological_process +def: "The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments." [GOC:krc, PMID:22319670, PMID:24440897, PMID:26792866] +synonym: "IMT" RELATED [] +is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism +is_a: GO:0031503 ! protein-containing complex localization +is_a: GO:0098840 ! protein transport along microtubule +relationship: occurs_in GO:0002177 ! manchette +relationship: part_of GO:0007286 ! spermatid development +created_by: krc +creation_date: 2016-05-11T00:17:56Z + +[Term] +id: GO:1990955 +name: G-rich single-stranded DNA binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with G-rich, single-stranded DNA." [GOC:hjd, PMID:8493094] +is_a: GO:0003697 ! single-stranded DNA binding +created_by: hjd +creation_date: 2016-05-13T17:44:28Z + +[Term] +id: GO:1990956 +name: fibroblast chemotaxis +namespace: biological_process +def: "The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." [GOC:dph, PMID:8760137] +is_a: GO:0060326 ! cell chemotaxis +created_by: dph +creation_date: 2016-06-02T19:54:19Z + +[Term] +id: GO:1990957 +name: NPHP complex +namespace: cellular_component +def: "A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways." [GOC:cilia, PMID:18337471, PMID:21422230, PMID:21498478, PMID:21555462, PMID:25150219] +comment: Although there is some evidence, it's still unclear if the MKS and NPHP complexes are constituent parts of the ciliary Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the cilium membrane and axoneme. +synonym: "NPHP module" EXACT [] +is_a: GO:0032991 ! protein-containing complex +relationship: part_of GO:0035869 ! ciliary transition zone +created_by: pr +creation_date: 2016-06-06T10:59:45Z + +[Term] +id: GO:1990958 +name: obsolete response to thyrotropin-releasing hormone +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary." [PMID:21382270] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "response to TRH" RELATED [] +is_obsolete: true +created_by: sl +creation_date: 2016-06-06T21:07:34Z + +[Term] +id: GO:1990959 +name: eosinophil homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus." [PMID:10606160] +synonym: "eosinocyte homeostasis" EXACT [] +synonym: "eosinophilic granulocyte homeostasis" EXACT [] +synonym: "eosinophilic leucocyte homeostasis" EXACT [] +synonym: "eosinophilic leukocyte homeostasis" EXACT [] +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis +created_by: sl +creation_date: 2016-06-06T22:34:31Z + +[Term] +id: GO:1990960 +name: basophil homeostasis +namespace: biological_process +def: "The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus." [PMID:10606160] +synonym: "basophilic leucocyte homeostasis" EXACT [] +is_a: GO:0001776 ! leukocyte homeostasis +is_a: GO:0002262 ! myeloid cell homeostasis +created_by: sl +creation_date: 2016-06-06T22:38:22Z + +[Term] +id: GO:1990961 +name: xenobiotic detoxification by transmembrane export across the plasma membrane +namespace: biological_process +def: "A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell." [PMID:28355133] +synonym: "drug transmembrane export" NARROW [] +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0140115 ! export across plasma membrane +relationship: part_of GO:0098754 ! detoxification +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/17141 xsd:anyURI +created_by: sl +creation_date: 2016-06-06T23:47:22Z + +[Term] +id: GO:1990962 +name: xenobiotic transport across blood-brain barrier +namespace: biological_process +def: "The directed movement of a xenobiotic through the blood-brain barrier." [PMID:25053619] +synonym: "drug transport across blood-brain barrier" RELATED [] +is_a: GO:0042908 ! xenobiotic transport +is_a: GO:0150104 ! transport across blood-brain barrier +created_by: sl +creation_date: 2016-06-07T17:39:33Z + +[Term] +id: GO:1990963 +name: establishment of blood-retinal barrier +namespace: biological_process +def: "Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type." [PMID:25053619] +synonym: "establishment of blood-retina barrier" EXACT [] +synonym: "establishment of BRB" RELATED [] +is_a: GO:0048468 ! cell development +created_by: sl +creation_date: 2016-06-07T21:17:55Z + +[Term] +id: GO:1990964 +name: actin cytoskeleton-regulatory complex +namespace: cellular_component +def: "A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat." [GOC:bhm, PMID:10594004, PMID:11739778] +comment: An example of this is Pan1 in Saccharomyces cerevisiae (UniProt ID P32521) in PMID:10594004 (inferred from direct assay). +xref: IntAct:EBI-11710254 +is_a: GO:0032991 ! protein-containing complex +created_by: bhm +creation_date: 2016-06-09T12:18:30Z + +[Term] +id: GO:1990965 +name: cytosylglucuronate decarboxylase activity +namespace: molecular_function +def: "Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2)." [GOC:pr, GOC:tb, PMID:23874663] +comment: This enzymatic activity was shown to be involved in the bacterial blasticidin S biosynthetic pathway. +is_a: GO:0016831 ! carboxy-lyase activity +created_by: pr +creation_date: 2016-06-09T13:05:27Z + +[Term] +id: GO:1990966 +name: ATP generation from poly-ADP-D-ribose +namespace: biological_process +def: "The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming." [PMID:27257257] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:0046034 ! ATP metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: sp +creation_date: 2016-06-16T09:41:35Z + +[Term] +id: GO:1990967 +name: obsolete multi-organism toxin transport +namespace: biological_process +def: "OBSOLETE. The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved." [GOC:bf, GOC:PARL, PMID:18191792, PMID:22042847] +comment: This term was obsoleted because there is no evidence that this process exists. +synonym: "typhoid toxin transport" NARROW [PMID:22042847] +is_obsolete: true +created_by: bf +creation_date: 2016-06-21T09:01:39Z + +[Term] +id: GO:1990968 +name: modulation by host of RNA binding by virus +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA." [GOC:bf, GOC:PARL, PMID:25116364] +comment: Note that the bound RNA may originate from the virus or another organism, including the host. +synonym: "modulation by host of viral protein:RNA interaction" RELATED [GOC:bf] +is_a: GO:0044868 ! modulation by host of viral molecular function +is_a: GO:1905214 ! regulation of RNA binding +created_by: bf +creation_date: 2016-06-21T11:56:10Z + +[Term] +id: GO:1990969 +name: modulation by host of viral RNA-binding transcription factor activity +namespace: biological_process +def: "A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor." [GOC:bf, GOC:PARL, PMID:25116364] +synonym: "modulation by host of viral Tat activity" NARROW [PMID:25116364] +is_a: GO:0043921 ! modulation by host of viral transcription +is_a: GO:0052428 ! modulation by host of symbiont molecular function +is_a: GO:1905255 ! regulation of RNA binding transcription factor activity +intersection_of: GO:0052428 ! modulation by host of symbiont molecular function +intersection_of: regulates GO:0001070 ! RNA-binding transcription regulator activity +created_by: bf +creation_date: 2016-06-21T12:12:31Z + +[Term] +id: GO:1990970 +name: trans-activation response element binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter." [GOC:bf, GOC:PARL, PMID:25116364, Wikipedia:Trans-activation_response_element_(TAR)] +synonym: "TAR binding" EXACT [PMID:25116364] +is_a: GO:0070883 ! pre-miRNA binding +created_by: bf +creation_date: 2016-06-21T12:23:00Z + +[Term] +id: GO:1990971 +name: EMILIN complex +namespace: cellular_component +def: "Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures." [GOC:bhm, PMID:10821830] +comment: An example of this is EMILIN-1 in human (Q9Y6C2) in PMID:10821830 (inferred from direct assay). +synonym: "Elastic microfibrillar interface 1 complex" NARROW [] +synonym: "Elastic microfibrillar interface 2 complex" NARROW [] +synonym: "EMILIN-1 complex" NARROW [] +synonym: "EMILIN-2 complex" NARROW [] +xref: IntAct:EBI-11705777 +xref: IntAct:EBI-11740139 +xref: IntAct:EBI-11740215 +xref: IntAct:EBI-11740275 +is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: bhm +creation_date: 2016-06-21T14:41:18Z + +[Term] +id: GO:1990972 +name: multimerin complex +namespace: cellular_component +def: "Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures." [GOC:bhm, PMID:9454761] +comment: An example of this is Multimerin-1 in human (Q13201) in PMID:9454761. +synonym: "Elastic microfibrillar interface 3 complex" NARROW [] +synonym: "Elastic microfibrillar interface 4 complex" NARROW [] +synonym: "EMILIN-3 complex" NARROW [] +synonym: "EMILIN-4 complex" NARROW [] +synonym: "Multimerin-1 complex" NARROW [] +synonym: "Multimerin-2 complex" NARROW [] +synonym: "p155 complex" NARROW [] +synonym: "Platelet glycoprotein Ia* complex" NARROW [] +xref: IntAct:EBI-11783711 +is_a: GO:0098637 ! protein complex involved in cell-matrix adhesion +relationship: part_of GO:0062023 ! collagen-containing extracellular matrix +created_by: bhm +creation_date: 2016-06-21T14:49:42Z + +[Term] +id: GO:1990973 +name: transmembrane actin-associated (TAN) line +namespace: cellular_component +def: "A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge)." [GOC:hjd, PMID:21173262] +synonym: "TAN line" RELATED [] +is_a: GO:0043232 ! intracellular non-membrane-bounded organelle +created_by: hjd +creation_date: 2016-06-22T15:05:09Z + +[Term] +id: GO:1990974 +name: actin-dependent nuclear migration +namespace: biological_process +def: "The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell." [GOC:hjd, PMID:21173262] +synonym: "actin-dependent nuclear movement" RELATED [] +is_a: GO:0007097 ! nuclear migration +created_by: hjd +creation_date: 2016-06-22T19:17:02Z + +[Term] +id: GO:1990976 +name: protein transport along microtubule to mitotic spindle pole body +namespace: biological_process +def: "The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins." [PMID:25987607] +is_a: GO:1902440 ! protein localization to mitotic spindle pole body +is_a: GO:1990852 ! protein transport along microtubule to spindle pole body +created_by: vw +creation_date: 2016-06-30T13:09:08Z + +[Term] +id: GO:1990977 +name: obsolete negative regulation of mitotic DNA replication initiation from late origin +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication." [PMID:26436827] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: al +creation_date: 2016-07-11T14:56:38Z + +[Term] +id: GO:1990978 +name: obsolete response to viscosity +namespace: biological_process +def: "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus." [PMID:7061416] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sl +creation_date: 2016-08-17T20:10:36Z + +[Term] +id: GO:1990979 +name: obsolete copper ion transport across blood-brain barrier +namespace: biological_process +def: "OBSOLETE. The directed movement of copper ions passing through the blood-brain barrier." [PMID:24614235] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "copper ion transport across BBB" RELATED [] +is_obsolete: true +created_by: sl +creation_date: 2016-08-17T21:09:08Z + +[Term] +id: GO:1990980 +name: obsolete copper ion transport across blood-CSF barrier +namespace: biological_process +def: "OBSOLETE. The directed movement of copper ions passing through the blood-cerebrospinal fluid barrier." [PMID:24614235] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +synonym: "copper ion transport across BCB" EXACT [] +synonym: "copper ion transport across blood-cerebrospinal fluid barrier" EXACT [] +is_obsolete: true +created_by: sl +creation_date: 2016-08-17T21:14:18Z + +[Term] +id: GO:1990981 +name: obsolete regulation of protein localization to cell division site involved in cell separation after cytokinesis +namespace: biological_process +def: "OBSOLETE. A regulation of protein localization to cell division site involved in cell separation after cytokinesis." [PMID:25411334] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: vw +creation_date: 2016-08-21T19:43:21Z + +[Term] +id: GO:1990982 +name: obsolete Immune memory response +namespace: biological_process +def: "OBSOLETE. The immune response against a previously encountered antigen being quicker and quantitatively better compared with the primary response." [PMID:26831526] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: sp +creation_date: 2016-09-01T10:57:56Z + +[Term] +id: GO:1990983 +name: tRNA demethylation +namespace: biological_process +def: "The removal of a methyl group from one or more residues within a tRNA molecule." [PMID:27745969] +is_a: GO:0006400 ! tRNA modification +is_a: GO:0035513 ! oxidative RNA demethylation +created_by: sp +creation_date: 2016-10-28T08:32:59Z + +[Term] +id: GO:1990984 +name: tRNA demethylase activity +namespace: molecular_function +def: "Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule." [PMID:27745969] +is_a: GO:0035515 ! oxidative RNA demethylase activity +is_a: GO:0140101 ! catalytic activity, acting on a tRNA +created_by: sp +creation_date: 2016-10-28T08:38:14Z + +[Term] +id: GO:1990985 +name: obsolete apoptosis in response to oxidative stress +namespace: biological_process +def: "OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to oxidative stress." [GOC:pg, PMID:25950479] +comment: This term was obsoleted at the TermGenie Gatekeeper stage. +is_obsolete: true +created_by: pg +creation_date: 2016-11-17T14:12:17Z + +[Term] +id: GO:1990986 +name: DNA recombinase disassembly +namespace: biological_process +def: "The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases)." [GOC:pg, PMID:19540122] +synonym: "Rad51 nucleoprotein filament disassembly" RELATED [] +is_a: GO:0032986 ! protein-DNA complex disassembly +is_a: GO:0043624 ! cellular protein complex disassembly +created_by: pg +creation_date: 2016-11-18T13:13:56Z + +[Term] +id: GO:2000001 +name: regulation of DNA damage checkpoint +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a DNA damage checkpoint." [GOC:obol] +synonym: "regulation of DNA damage response, signal transduction resulting in cell cycle arrest" RELATED [GOC:obol] +is_a: GO:1901976 ! regulation of cell cycle checkpoint +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000077 ! DNA damage checkpoint +relationship: regulates GO:0000077 ! DNA damage checkpoint +created_by: jl +creation_date: 2010-07-15T03:25:00Z + +[Term] +id: GO:2000002 +name: negative regulation of DNA damage checkpoint +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint." [GOC:BHF, GOC:obol] +synonym: "negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest" RELATED [GOC:obol] +is_a: GO:1901977 ! negative regulation of cell cycle checkpoint +is_a: GO:2000001 ! regulation of DNA damage checkpoint +is_a: GO:2001021 ! negative regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000077 ! DNA damage checkpoint +relationship: negatively_regulates GO:0000077 ! DNA damage checkpoint +created_by: jl +creation_date: 2010-07-15T03:25:06Z + +[Term] +id: GO:2000003 +name: positive regulation of DNA damage checkpoint +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint." [GOC:obol] +synonym: "positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest" RELATED [GOC:obol] +is_a: GO:1901978 ! positive regulation of cell cycle checkpoint +is_a: GO:2000001 ! regulation of DNA damage checkpoint +is_a: GO:2001022 ! positive regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000077 ! DNA damage checkpoint +relationship: positively_regulates GO:0000077 ! DNA damage checkpoint +created_by: jl +creation_date: 2010-07-15T03:25:10Z + +[Term] +id: GO:2000004 +name: regulation of metanephric S-shaped body morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072284 ! metanephric S-shaped body morphogenesis +relationship: regulates GO:0072284 ! metanephric S-shaped body morphogenesis +created_by: jl +creation_date: 2010-07-30T02:14:33Z + +[Term] +id: GO:2000005 +name: negative regulation of metanephric S-shaped body morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000004 ! regulation of metanephric S-shaped body morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072284 ! metanephric S-shaped body morphogenesis +relationship: negatively_regulates GO:0072284 ! metanephric S-shaped body morphogenesis +created_by: jl +creation_date: 2010-07-30T02:14:37Z + +[Term] +id: GO:2000006 +name: regulation of metanephric comma-shaped body morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072278 ! metanephric comma-shaped body morphogenesis +relationship: regulates GO:0072278 ! metanephric comma-shaped body morphogenesis +created_by: jl +creation_date: 2010-07-30T02:17:12Z + +[Term] +id: GO:2000007 +name: negative regulation of metanephric comma-shaped body morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000006 ! regulation of metanephric comma-shaped body morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072278 ! metanephric comma-shaped body morphogenesis +relationship: negatively_regulates GO:0072278 ! metanephric comma-shaped body morphogenesis +created_by: jl +creation_date: 2010-07-30T02:17:17Z + +[Term] +id: GO:2000008 +name: regulation of protein localization to cell surface +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to the cell surface." [GOC:obol] +synonym: "regulation of protein localisation at cell surface" EXACT [GOC:mah] +synonym: "regulation of protein localization at cell surface" EXACT [] +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034394 ! protein localization to cell surface +relationship: regulates GO:0034394 ! protein localization to cell surface +created_by: jl +creation_date: 2010-08-04T01:43:48Z + +[Term] +id: GO:2000009 +name: negative regulation of protein localization to cell surface +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface." [GOC:obol] +synonym: "negative regulation of protein localisation at cell surface" EXACT [GOC:mah] +synonym: "negative regulation of protein localization at cell surface" EXACT [] +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:2000008 ! regulation of protein localization to cell surface +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034394 ! protein localization to cell surface +relationship: negatively_regulates GO:0034394 ! protein localization to cell surface +created_by: jl +creation_date: 2010-08-04T01:43:52Z + +[Term] +id: GO:2000010 +name: positive regulation of protein localization to cell surface +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface." [GOC:obol] +synonym: "positive regulation of protein localisation at cell surface" EXACT [GOC:mah] +synonym: "positive regulation of protein localization at cell surface" EXACT [] +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:2000008 ! regulation of protein localization to cell surface +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034394 ! protein localization to cell surface +relationship: positively_regulates GO:0034394 ! protein localization to cell surface +created_by: jl +creation_date: 2010-08-04T01:43:56Z + +[Term] +id: GO:2000011 +name: regulation of adaxial/abaxial pattern formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation." [GOC:obol] +synonym: "regulation of adaxial/abaxial pattern specification" RELATED [GOC:obol] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009955 ! adaxial/abaxial pattern specification +relationship: regulates GO:0009955 ! adaxial/abaxial pattern specification +created_by: tb +creation_date: 2010-08-05T11:20:22Z + +[Term] +id: GO:2000012 +name: regulation of auxin polar transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of auxin polar transport." [GOC:obol] +is_a: GO:0010817 ! regulation of hormone levels +is_a: GO:0051049 ! regulation of transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009926 ! auxin polar transport +relationship: regulates GO:0009926 ! auxin polar transport +created_by: tb +creation_date: 2010-08-05T11:21:09Z + +[Term] +id: GO:2000013 +name: regulation of arginine biosynthetic process via ornithine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine." [GOC:obol] +synonym: "regulation of arginine anabolism via ornithine" EXACT [GOC:obol] +synonym: "regulation of arginine formation via ornithine" EXACT [GOC:obol] +synonym: "regulation of arginine synthesis via ornithine" EXACT [GOC:obol] +is_a: GO:0090368 ! regulation of ornithine metabolic process +is_a: GO:1900079 ! regulation of arginine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042450 ! arginine biosynthetic process via ornithine +relationship: regulates GO:0042450 ! arginine biosynthetic process via ornithine +created_by: tb +creation_date: 2010-08-05T11:21:51Z + +[Term] +id: GO:2000014 +name: regulation of endosperm development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endosperm development." [GOC:obol] +is_a: GO:0080050 ! regulation of seed development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009960 ! endosperm development +relationship: regulates GO:0009960 ! endosperm development +created_by: tb +creation_date: 2010-08-05T11:22:21Z + +[Term] +id: GO:2000015 +name: regulation of determination of dorsal identity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of determination of dorsal identity." [GOC:obol] +synonym: "regulation of determination of adaxial identity" RELATED [GOC:obol] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048263 ! determination of dorsal identity +relationship: regulates GO:0048263 ! determination of dorsal identity +created_by: jl +creation_date: 2010-07-15T03:27:49Z + +[Term] +id: GO:2000016 +name: negative regulation of determination of dorsal identity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity." [GOC:BHF, GOC:obol] +synonym: "negative regulation of determination of adaxial identity" RELATED [GOC:obol] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000015 ! regulation of determination of dorsal identity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048263 ! determination of dorsal identity +relationship: negatively_regulates GO:0048263 ! determination of dorsal identity +created_by: jl +creation_date: 2010-07-15T03:27:55Z + +[Term] +id: GO:2000017 +name: positive regulation of determination of dorsal identity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of determination of dorsal identity." [GOC:obol] +synonym: "positive regulation of determination of adaxial identity" RELATED [GOC:obol] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000015 ! regulation of determination of dorsal identity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048263 ! determination of dorsal identity +relationship: positively_regulates GO:0048263 ! determination of dorsal identity +created_by: jl +creation_date: 2010-07-15T03:27:59Z + +[Term] +id: GO:2000018 +name: regulation of male gonad development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] +synonym: "regulation of testicular development" EXACT [GOC:obol] +synonym: "regulation of testis development" EXACT [GOC:obol] +is_a: GO:1905939 ! regulation of gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008584 ! male gonad development +relationship: regulates GO:0008584 ! male gonad development +created_by: jl +creation_date: 2010-07-15T03:29:05Z + +[Term] +id: GO:2000019 +name: negative regulation of male gonad development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] +synonym: "negative regulation of testicular development" EXACT [GOC:obol] +synonym: "negative regulation of testis development" EXACT [GOC:obol] +is_a: GO:1905940 ! negative regulation of gonad development +is_a: GO:2000018 ! regulation of male gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008584 ! male gonad development +relationship: negatively_regulates GO:0008584 ! male gonad development +created_by: jl +creation_date: 2010-07-15T03:29:10Z + +[Term] +id: GO:2000020 +name: positive regulation of male gonad development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol] +synonym: "positive regulation of testicular development" EXACT [GOC:obol] +synonym: "positive regulation of testis development" EXACT [GOC:obol] +is_a: GO:1905941 ! positive regulation of gonad development +is_a: GO:2000018 ! regulation of male gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008584 ! male gonad development +relationship: positively_regulates GO:0008584 ! male gonad development +created_by: jl +creation_date: 2010-07-15T03:29:13Z + +[Term] +id: GO:2000022 +name: regulation of jasmonic acid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway." [GOC:obol] +synonym: "regulation of jasmonic acid mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009867 ! jasmonic acid mediated signaling pathway +relationship: regulates GO:0009867 ! jasmonic acid mediated signaling pathway +created_by: tb +creation_date: 2010-08-05T11:24:11Z + +[Term] +id: GO:2000023 +name: regulation of lateral root development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lateral root development." [GOC:obol] +is_a: GO:2000069 ! regulation of post-embryonic root development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048527 ! lateral root development +relationship: regulates GO:0048527 ! lateral root development +created_by: tb +creation_date: 2010-08-05T11:24:50Z + +[Term] +id: GO:2000024 +name: regulation of leaf development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leaf development." [GOC:obol] +is_a: GO:0048831 ! regulation of shoot system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048366 ! leaf development +relationship: regulates GO:0048366 ! leaf development +created_by: tb +creation_date: 2010-08-05T11:25:14Z + +[Term] +id: GO:2000025 +name: regulation of leaf formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leaf formation." [GOC:obol] +is_a: GO:1901371 ! regulation of leaf morphogenesis +is_a: GO:1905428 ! regulation of plant organ formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010338 ! leaf formation +relationship: regulates GO:0010338 ! leaf formation +created_by: tb +creation_date: 2010-08-05T11:25:37Z + +[Term] +id: GO:2000026 +name: regulation of multicellular organismal development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007275 ! multicellular organism development +relationship: regulates GO:0007275 ! multicellular organism development +created_by: tb +creation_date: 2010-08-05T11:25:59Z + +[Term] +id: GO:2000027 +name: regulation of animal organ morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol] +synonym: "regulation of histogenesis and organogenesis" RELATED [GOC:obol] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0009887 ! animal organ morphogenesis +relationship: regulates GO:0009887 ! animal organ morphogenesis +created_by: tb +creation_date: 2010-08-05T11:26:27Z + +[Term] +id: GO:2000028 +name: regulation of photoperiodism, flowering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of photoperiodism, flowering." [GOC:obol] +synonym: "regulation of photoperiodic control of flowering time" EXACT [GOC:obol] +synonym: "regulation of photoperiodic control of inflorescence development" EXACT [GOC:obol] +synonym: "regulation of response to day length, flowering" EXACT [GOC:obol] +synonym: "regulation of response to night length, flowering" EXACT [GOC:obol] +synonym: "regulation of response to photoperiod, flowering" EXACT [GOC:obol] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048573 ! photoperiodism, flowering +relationship: regulates GO:0048573 ! photoperiodism, flowering +created_by: tb +creation_date: 2010-08-05T11:27:18Z + +[Term] +id: GO:2000029 +name: regulation of proanthocyanidin biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process." [GOC:obol] +synonym: "regulation of proanthocyanidin anabolism" EXACT [GOC:obol] +synonym: "regulation of proanthocyanidin biosynthesis" EXACT [GOC:obol] +synonym: "regulation of proanthocyanidin formation" EXACT [GOC:obol] +synonym: "regulation of proanthocyanidin synthesis" EXACT [GOC:obol] +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process +is_a: GO:2000762 ! regulation of phenylpropanoid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010023 ! proanthocyanidin biosynthetic process +relationship: regulates GO:0010023 ! proanthocyanidin biosynthetic process +created_by: tb +creation_date: 2010-08-05T11:28:08Z + +[Term] +id: GO:2000030 +name: regulation of response to red or far red light +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to red or far red light." [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009639 ! response to red or far red light +relationship: regulates GO:0009639 ! response to red or far red light +created_by: tb +creation_date: 2010-08-05T11:30:10Z + +[Term] +id: GO:2000031 +name: regulation of salicylic acid mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway." [GOC:obol] +synonym: "regulation of salicylic acid mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:2001038 ! regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009863 ! salicylic acid mediated signaling pathway +relationship: regulates GO:0009863 ! salicylic acid mediated signaling pathway +created_by: tb +creation_date: 2010-08-05T11:32:24Z + +[Term] +id: GO:2000032 +name: regulation of secondary shoot formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary shoot formation." [GOC:obol] +synonym: "regulation of auxiliary shoot formation" RELATED [GOC:obol] +synonym: "regulation of axillary shoot formation" RELATED [GOC:obol] +synonym: "regulation of axillary shoot system formation" EXACT [] +synonym: "regulation of shoot branching" RELATED [] +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +is_a: GO:1900618 ! regulation of shoot system morphogenesis +is_a: GO:1905428 ! regulation of plant organ formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010223 ! secondary shoot formation +relationship: regulates GO:0010223 ! secondary shoot formation +created_by: tb +creation_date: 2010-08-05T11:32:50Z + +[Term] +id: GO:2000033 +name: regulation of seed dormancy process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of seed dormancy process." [GOC:obol, GOC:pr, ISBN:9781405139830] +synonym: "regulation of seed dormancy" RELATED [] +is_a: GO:2000034 ! regulation of seed maturation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010162 ! seed dormancy process +relationship: regulates GO:0010162 ! seed dormancy process +created_by: tb +creation_date: 2010-08-05T11:33:13Z + +[Term] +id: GO:2000034 +name: regulation of seed maturation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of seed maturation." [GOC:obol] +is_a: GO:0080050 ! regulation of seed development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010431 ! seed maturation +relationship: regulates GO:0010431 ! seed maturation +created_by: tb +creation_date: 2010-08-05T11:33:33Z + +[Term] +id: GO:2000035 +name: regulation of stem cell division +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol] +synonym: "regulation of stem cell renewal" EXACT [GOC:obol] +is_a: GO:0051302 ! regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017145 ! stem cell division +relationship: regulates GO:0017145 ! stem cell division +created_by: tb +creation_date: 2010-08-05T11:34:53Z + +[Term] +id: GO:2000036 +name: regulation of stem cell population maintenance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol] +synonym: "regulation of maintenance of pluripotency" RELATED [GOC:obol] +is_a: GO:0050793 ! regulation of developmental process +is_a: GO:0051239 ! regulation of multicellular organismal process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019827 ! stem cell population maintenance +relationship: regulates GO:0019827 ! stem cell population maintenance +created_by: tb +creation_date: 2010-08-05T11:35:25Z + +[Term] +id: GO:2000037 +name: regulation of stomatal complex patterning +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stomatal complex patterning." [GOC:obol] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010375 ! stomatal complex patterning +relationship: regulates GO:0010375 ! stomatal complex patterning +created_by: tb +creation_date: 2010-08-05T11:35:47Z + +[Term] +id: GO:2000038 +name: regulation of stomatal complex development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stomatal complex development." [GOC:obol] +is_a: GO:0048580 ! regulation of post-embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010374 ! stomatal complex development +relationship: regulates GO:0010374 ! stomatal complex development +created_by: tb +creation_date: 2010-08-05T11:36:10Z + +[Term] +id: GO:2000039 +name: regulation of trichome morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of trichome morphogenesis." [GOC:obol] +synonym: "regulation of trichome cell morphogenesis during differentiation" EXACT [GOC:obol] +is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation +is_a: GO:2000024 ! regulation of leaf development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010090 ! trichome morphogenesis +relationship: regulates GO:0010090 ! trichome morphogenesis +created_by: tb +creation_date: 2010-08-05T11:36:31Z + +[Term] +id: GO:2000040 +name: regulation of planar cell polarity pathway involved in axis elongation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation." [GOC:dph] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:2000095 ! regulation of Wnt signaling pathway, planar cell polarity pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003402 ! planar cell polarity pathway involved in axis elongation +relationship: regulates GO:0003402 ! planar cell polarity pathway involved in axis elongation +created_by: dph +creation_date: 2010-08-18T02:47:49Z + +[Term] +id: GO:2000041 +name: negative regulation of planar cell polarity pathway involved in axis elongation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation." [GOC:dph] +is_a: GO:0048640 ! negative regulation of developmental growth +is_a: GO:2000040 ! regulation of planar cell polarity pathway involved in axis elongation +is_a: GO:2000051 ! negative regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003402 ! planar cell polarity pathway involved in axis elongation +relationship: negatively_regulates GO:0003402 ! planar cell polarity pathway involved in axis elongation +created_by: dph +creation_date: 2010-08-18T02:47:54Z + +[Term] +id: GO:2000042 +name: negative regulation of double-strand break repair via homologous recombination +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination." [GOC:vw] +synonym: "negative regulation of HDR" EXACT [GOC:obol] +synonym: "negative regulation of homologous recombinational repair" EXACT [GOC:obol] +synonym: "negative regulation of homology-directed repair" EXACT [GOC:obol] +synonym: "negative regulation of HRR" EXACT [GOC:obol] +synonym: "negative regulation of Rad51-dependent recombinational repair" EXACT [GOC:obol] +synonym: "negative regulation of Rhp51-dependent recombinational repair" EXACT [GOC:obol] +is_a: GO:0010569 ! regulation of double-strand break repair via homologous recombination +is_a: GO:0045910 ! negative regulation of DNA recombination +is_a: GO:2000780 ! negative regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000724 ! double-strand break repair via homologous recombination +relationship: negatively_regulates GO:0000724 ! double-strand break repair via homologous recombination +created_by: tb +creation_date: 2010-08-19T06:37:08Z + +[Term] +id: GO:2000043 +name: regulation of cardiac cell fate specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac cell fate specification." [GOC:BHF] +is_a: GO:0042659 ! regulation of cell fate specification +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060912 ! cardiac cell fate specification +relationship: regulates GO:0060912 ! cardiac cell fate specification +created_by: tb +creation_date: 2010-08-19T09:01:04Z + +[Term] +id: GO:2000044 +name: negative regulation of cardiac cell fate specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification." [GOC:BHF] +is_a: GO:0009996 ! negative regulation of cell fate specification +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +is_a: GO:2000043 ! regulation of cardiac cell fate specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060912 ! cardiac cell fate specification +relationship: negatively_regulates GO:0060912 ! cardiac cell fate specification +created_by: tb +creation_date: 2010-08-19T09:01:10Z + +[Term] +id: GO:2000045 +name: regulation of G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] +comment: Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'. +is_a: GO:1901990 ! regulation of mitotic cell cycle phase transition +is_a: GO:1902806 ! regulation of cell cycle G1/S phase transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000082 ! G1/S transition of mitotic cell cycle +relationship: regulates GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: tb +creation_date: 2010-08-19T09:10:56Z + +[Term] +id: GO:2000046 +name: obsolete regulation of G2 phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of G2 phase of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:vw] +comment: This term was made obsolete because we felt that phases themselves are not being regulated, it's rather the transitions between phases. If you are trying to make an annotation to x phase, it is likely that the correct process is 'regulation of x/y phase transiition. +synonym: "regulation of G2 phase of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0010389 +created_by: tb +creation_date: 2010-08-19T09:19:18Z + +[Term] +id: GO:2000047 +name: regulation of cell-cell adhesion mediated by cadherin +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin." [GOC:obol] +is_a: GO:0022407 ! regulation of cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +relationship: regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +created_by: jl +creation_date: 2010-08-20T12:56:44Z + +[Term] +id: GO:2000048 +name: negative regulation of cell-cell adhesion mediated by cadherin +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin." [GOC:obol] +is_a: GO:0022408 ! negative regulation of cell-cell adhesion +is_a: GO:2000047 ! regulation of cell-cell adhesion mediated by cadherin +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +relationship: negatively_regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +created_by: jl +creation_date: 2010-08-20T12:56:51Z + +[Term] +id: GO:2000049 +name: positive regulation of cell-cell adhesion mediated by cadherin +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin." [GOC:obol] +is_a: GO:0022409 ! positive regulation of cell-cell adhesion +is_a: GO:2000047 ! regulation of cell-cell adhesion mediated by cadherin +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +relationship: positively_regulates GO:0044331 ! cell-cell adhesion mediated by cadherin +created_by: jl +creation_date: 2010-08-20T12:56:57Z + +[Term] +id: GO:2000050 +name: regulation of non-canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway." [GOC:obol, GOC:yaf] +synonym: "regulation of beta-catenin-independent Wnt receptor signaling pathway" EXACT [GOC:obol] +synonym: "regulation of non-canonical Wnt receptor signaling pathway" EXACT [] +synonym: "regulation of non-canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of non-canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035567 ! non-canonical Wnt signaling pathway +relationship: regulates GO:0035567 ! non-canonical Wnt signaling pathway +created_by: jl +creation_date: 2010-08-20T01:04:12Z + +[Term] +id: GO:2000051 +name: negative regulation of non-canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway." [GOC:obol, GOC:yaf] +synonym: "negative regulation of beta-catenin-independent Wnt receptor signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of non-canonical Wnt receptor signaling pathway" EXACT [] +synonym: "negative regulation of non-canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of non-canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:2000050 ! regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035567 ! non-canonical Wnt signaling pathway +relationship: negatively_regulates GO:0035567 ! non-canonical Wnt signaling pathway +created_by: jl +creation_date: 2010-08-20T01:04:20Z + +[Term] +id: GO:2000052 +name: positive regulation of non-canonical Wnt signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway." [GOC:obol, GOC:yaf] +synonym: "positive regulation of beta-catenin-independent Wnt receptor signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of non-canonical Wnt receptor signaling pathway" EXACT [] +synonym: "positive regulation of non-canonical Wnt receptor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of non-canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:2000050 ! regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035567 ! non-canonical Wnt signaling pathway +relationship: positively_regulates GO:0035567 ! non-canonical Wnt signaling pathway +created_by: jl +creation_date: 2010-08-20T01:04:25Z + +[Term] +id: GO:2000053 +name: regulation of Wnt signaling pathway involved in dorsal/ventral axis specification +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification." [GOC:obol, GOC:yaf] +synonym: "regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification" EXACT [GOC:mah] +synonym: "regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification" EXACT [GOC:signaling] +is_a: GO:0030111 ! regulation of Wnt signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +relationship: regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +created_by: jl +creation_date: 2010-08-20T01:13:28Z + +[Term] +id: GO:2000054 +name: negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification." [GOC:obol, GOC:yaf] +synonym: "negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification" EXACT [] +synonym: "negative regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification" EXACT [GOC:mah] +synonym: "negative regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification" EXACT [GOC:signaling] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000053 ! regulation of Wnt signaling pathway involved in dorsal/ventral axis specification +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +relationship: negatively_regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +created_by: jl +creation_date: 2010-08-20T01:13:35Z + +[Term] +id: GO:2000055 +name: positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification." [GOC:obol] +synonym: "positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification" EXACT [] +synonym: "positive regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification" EXACT [GOC:mah] +synonym: "positive regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification" EXACT [GOC:signaling] +is_a: GO:0030177 ! positive regulation of Wnt signaling pathway +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000053 ! regulation of Wnt signaling pathway involved in dorsal/ventral axis specification +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +relationship: positively_regulates GO:0044332 ! Wnt signaling pathway involved in dorsal/ventral axis specification +created_by: jl +creation_date: 2010-08-20T01:13:40Z + +[Term] +id: GO:2000056 +name: regulation of Wnt signaling pathway involved in digestive tract morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis." [GOC:obol] +synonym: "regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis" EXACT [GOC:mah] +synonym: "regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis" RELATED [GOC:signaling] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0030111 ! regulation of Wnt signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044333 ! Wnt signaling pathway involved in digestive tract morphogenesis +relationship: regulates GO:0044333 ! Wnt signaling pathway involved in digestive tract morphogenesis +created_by: jl +creation_date: 2010-08-20T01:17:27Z + +[Term] +id: GO:2000057 +name: negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis." [GOC:obol] +synonym: "negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis" EXACT [] +synonym: "negative regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis" EXACT [GOC:mah] +synonym: "negative regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis" EXACT [GOC:signaling] +is_a: GO:0030178 ! negative regulation of Wnt signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000056 ! regulation of Wnt signaling pathway involved in digestive tract morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044333 ! Wnt signaling pathway involved in digestive tract morphogenesis +relationship: negatively_regulates GO:0044333 ! Wnt signaling pathway involved in digestive tract morphogenesis +created_by: jl +creation_date: 2010-08-20T01:17:35Z + +[Term] +id: GO:2000058 +name: regulation of ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process." [GOC:BHF] +synonym: "regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown" RELATED [GOC:obol] +synonym: "regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process" RELATED [GOC:obol] +synonym: "regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism" RELATED [GOC:obol] +synonym: "regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation" RELATED [GOC:obol] +synonym: "regulation of protein degradation tagging activity" RELATED [GOC:obol] +synonym: "regulation of protein ubiquitination during ubiquitin-dependent protein breakdown" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process" RELATED [GOC:obol] +synonym: "regulation of protein ubiquitination during ubiquitin-dependent protein catabolism" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitination during ubiquitin-dependent protein degradation" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" EXACT [GOC:obol] +synonym: "regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" EXACT [GOC:obol] +is_a: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +created_by: jl +creation_date: 2010-08-20T01:23:46Z + +[Term] +id: GO:2000059 +name: negative regulation of ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process." [GOC:BHF] +synonym: "negative regulation of protein degradation tagging activity" BROAD [GOC:obol] +synonym: "negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol] +synonym: "negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +is_a: GO:1903051 ! negative regulation of proteolysis involved in cellular protein catabolic process +is_a: GO:2000058 ! regulation of ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: negatively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +created_by: jl +creation_date: 2010-08-20T01:23:56Z + +[Term] +id: GO:2000060 +name: positive regulation of ubiquitin-dependent protein catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process." [GOC:BHF] +synonym: "positive regulation of protein degradation tagging activity" RELATED [GOC:obol] +synonym: "positive regulation of protein ubiquitination during ubiquitin-dependent protein breakdown" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitination during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitination during ubiquitin-dependent protein degradation" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process" NARROW [] +synonym: "positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process" NARROW [GOC:obol] +synonym: "positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism" NARROW [GOC:obol] +is_a: GO:1903052 ! positive regulation of proteolysis involved in cellular protein catabolic process +is_a: GO:2000058 ! regulation of ubiquitin-dependent protein catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +relationship: positively_regulates GO:0006511 ! ubiquitin-dependent protein catabolic process +created_by: jl +creation_date: 2010-08-20T01:24:03Z + +[Term] +id: GO:2000061 +name: regulation of ureter smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0048634 ! regulation of muscle organ development +is_a: GO:0051150 ! regulation of smooth muscle cell differentiation +is_a: GO:1905899 ! regulation of smooth muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072193 ! ureter smooth muscle cell differentiation +relationship: regulates GO:0072193 ! ureter smooth muscle cell differentiation +created_by: jl +creation_date: 2010-08-20T01:44:16Z + +[Term] +id: GO:2000062 +name: negative regulation of ureter smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:1905900 ! negative regulation of smooth muscle tissue development +is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation +relationship: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation +created_by: jl +creation_date: 2010-08-20T01:44:23Z + +[Term] +id: GO:2000063 +name: positive regulation of ureter smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:1905901 ! positive regulation of smooth muscle tissue development +is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation +relationship: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation +created_by: jl +creation_date: 2010-08-20T01:44:28Z + +[Term] +id: GO:2000064 +name: regulation of cortisol biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cortisol biosynthetic process." [GOC:obol, GOC:yaf] +synonym: "regulation of cortisol anabolism" RELATED [GOC:obol] +synonym: "regulation of cortisol biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cortisol formation" EXACT [GOC:obol] +synonym: "regulation of cortisol synthesis" EXACT [GOC:obol] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0031946 ! regulation of glucocorticoid biosynthetic process +is_a: GO:1902930 ! regulation of alcohol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034651 ! cortisol biosynthetic process +relationship: regulates GO:0034651 ! cortisol biosynthetic process +created_by: jl +creation_date: 2010-08-20T01:51:15Z + +[Term] +id: GO:2000065 +name: negative regulation of cortisol biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process." [GOC:obol, GOC:yaf] +synonym: "negative regulation of cortisol anabolism" RELATED [GOC:obol] +synonym: "negative regulation of cortisol biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cortisol formation" EXACT [GOC:obol] +synonym: "negative regulation of cortisol synthesis" EXACT [GOC:obol] +is_a: GO:0031947 ! negative regulation of glucocorticoid biosynthetic process +is_a: GO:1902931 ! negative regulation of alcohol biosynthetic process +is_a: GO:2000064 ! regulation of cortisol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034651 ! cortisol biosynthetic process +relationship: negatively_regulates GO:0034651 ! cortisol biosynthetic process +created_by: jl +creation_date: 2010-08-20T01:51:23Z + +[Term] +id: GO:2000066 +name: positive regulation of cortisol biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process." [GOC:obol, GOC:yaf] +synonym: "positive regulation of cortisol anabolism" RELATED [GOC:obol] +synonym: "positive regulation of cortisol biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cortisol formation" EXACT [GOC:obol] +synonym: "positive regulation of cortisol synthesis" EXACT [GOC:obol] +is_a: GO:0031948 ! positive regulation of glucocorticoid biosynthetic process +is_a: GO:1902932 ! positive regulation of alcohol biosynthetic process +is_a: GO:2000064 ! regulation of cortisol biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034651 ! cortisol biosynthetic process +relationship: positively_regulates GO:0034651 ! cortisol biosynthetic process +created_by: jl +creation_date: 2010-08-20T01:51:32Z + +[Term] +id: GO:2000067 +name: regulation of root morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of root morphogenesis." [GOC:obol] +is_a: GO:1905421 ! regulation of plant organ morphogenesis +is_a: GO:2000280 ! regulation of root development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010015 ! root morphogenesis +relationship: regulates GO:0010015 ! root morphogenesis +created_by: tb +creation_date: 2010-08-23T09:25:13Z + +[Term] +id: GO:2000068 +name: regulation of defense response to insect +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol] +synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol] +is_a: GO:0002831 ! regulation of response to biotic stimulus +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032101 ! regulation of response to external stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002213 ! defense response to insect +relationship: regulates GO:0002213 ! defense response to insect +created_by: tb +creation_date: 2010-08-23T09:30:00Z + +[Term] +id: GO:2000069 +name: regulation of post-embryonic root development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of post-embryonic root development." [GOC:obol] +is_a: GO:0048580 ! regulation of post-embryonic development +is_a: GO:2000280 ! regulation of root development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048528 ! post-embryonic root development +relationship: regulates GO:0048528 ! post-embryonic root development +created_by: tb +creation_date: 2010-08-23T11:31:32Z + +[Term] +id: GO:2000070 +name: regulation of response to water deprivation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to water deprivation." [GOC:obol] +synonym: "regulation of drought tolerance" RELATED [GOC:obol] +synonym: "regulation of response to dehydration" EXACT [GOC:obol] +synonym: "regulation of response to drought" EXACT [GOC:obol] +synonym: "regulation of response to thirst" EXACT [GOC:obol] +is_a: GO:0080134 ! regulation of response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009414 ! response to water deprivation +relationship: regulates GO:0009414 ! response to water deprivation +created_by: tb +creation_date: 2010-08-23T11:32:32Z + +[Term] +id: GO:2000071 +name: regulation of defense response by callose deposition +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response by callose deposition." [GOC:obol] +synonym: "regulation of callose deposition during defense response" RELATED [GOC:obol] +synonym: "regulation of callose localization during defense response" RELATED [GOC:obol] +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0032879 ! regulation of localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052542 ! defense response by callose deposition +relationship: regulates GO:0052542 ! defense response by callose deposition +created_by: tb +creation_date: 2010-08-23T11:34:01Z + +[Term] +id: GO:2000072 +name: regulation of defense response to fungus, incompatible interaction +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defense response to fungus, incompatible interaction." [GOC:obol] +synonym: "regulation of defence response to fungus, incompatible interaction" EXACT [GOC:obol] +synonym: "regulation of defence response to pathogenic fungi, incompatible interaction" EXACT [GOC:obol] +synonym: "regulation of defence response to pathogenic fungus, incompatible interaction" EXACT [GOC:obol] +synonym: "regulation of defense response to fungi, incompatible interaction" EXACT [GOC:obol] +synonym: "regulation of resistance response to pathogenic fungi" EXACT [GOC:obol] +synonym: "regulation of resistance response to pathogenic fungus" EXACT [GOC:obol] +synonym: "regulation of response to pathogenic fungi (incompatible interaction)" EXACT [GOC:obol] +synonym: "regulation of response to pathogenic fungus (incompatible interaction)" EXACT [GOC:obol] +is_a: GO:0045088 ! regulation of innate immune response +is_a: GO:1900150 ! regulation of defense response to fungus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009817 ! defense response to fungus, incompatible interaction +relationship: regulates GO:0009817 ! defense response to fungus, incompatible interaction +created_by: tb +creation_date: 2010-08-23T11:34:52Z + +[Term] +id: GO:2000073 +name: regulation of cytokinesis, site selection +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis." [GOC:mtg_cell_cycle, GOC:obol] +synonym: "regulation of site selection involved in cell cycle cytokinesis" EXACT [] +is_a: GO:0032954 ! regulation of cytokinetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007105 ! cytokinesis, site selection +relationship: regulates GO:0007105 ! cytokinesis, site selection +created_by: tb +creation_date: 2010-08-27T11:15:15Z + +[Term] +id: GO:2000074 +name: regulation of type B pancreatic cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] +synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah] +synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0060284 ! regulation of cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003323 ! type B pancreatic cell development +relationship: regulates GO:0003323 ! type B pancreatic cell development +created_by: tb +creation_date: 2010-08-27T11:19:37Z + +[Term] +id: GO:2000075 +name: negative regulation of cytokinesis, site selection +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis." [GOC:mtg_cell_cycle, GOC:obol] +synonym: "negative regulation of site selection involved in cell cycle cytokinesis" EXACT [] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:2000073 ! regulation of cytokinesis, site selection +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007105 ! cytokinesis, site selection +relationship: negatively_regulates GO:0007105 ! cytokinesis, site selection +created_by: tb +creation_date: 2010-08-27T11:19:56Z + +[Term] +id: GO:2000076 +name: positive regulation cytokinesis, site selection +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis." [GOC:mtg_cell_cycle, GOC:obol] +synonym: "positive regulation of site selection involved in cell cycle cytokinesis" EXACT [] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:2000073 ! regulation of cytokinesis, site selection +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007105 ! cytokinesis, site selection +relationship: positively_regulates GO:0007105 ! cytokinesis, site selection +created_by: tb +creation_date: 2010-08-27T11:19:58Z + +[Term] +id: GO:2000077 +name: negative regulation of type B pancreatic cell development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] +synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah] +synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000074 ! regulation of type B pancreatic cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003323 ! type B pancreatic cell development +relationship: negatively_regulates GO:0003323 ! type B pancreatic cell development +created_by: tb +creation_date: 2010-08-27T11:21:17Z + +[Term] +id: GO:2000078 +name: positive regulation of type B pancreatic cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] +synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah] +synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000074 ! regulation of type B pancreatic cell development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003323 ! type B pancreatic cell development +relationship: positively_regulates GO:0003323 ! type B pancreatic cell development +created_by: tb +creation_date: 2010-08-27T11:21:19Z + +[Term] +id: GO:2000079 +name: regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation." [GOC:obol, GOC:yaf] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [] +synonym: "regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation" EXACT [GOC:obol] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:mah] +synonym: "regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:signaling] +is_a: GO:0060828 ! regulation of canonical Wnt signaling pathway +is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +relationship: regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +created_by: tb +creation_date: 2010-08-27T11:22:56Z + +[Term] +id: GO:2000080 +name: negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation." [GOC:obol, GOC:yaf] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [] +synonym: "negative regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation" EXACT [GOC:obol] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:mah] +synonym: "negative regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:signaling] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0090090 ! negative regulation of canonical Wnt signaling pathway +is_a: GO:2000079 ! regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +relationship: negatively_regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +created_by: tb +creation_date: 2010-08-27T11:22:58Z + +[Term] +id: GO:2000081 +name: positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation." [GOC:obol, GOC:yaf] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [] +synonym: "positive regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation" EXACT [GOC:obol] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation" EXACT [GOC:mah] +synonym: "positive regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:mah] +synonym: "positive regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation" EXACT [GOC:signaling] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0090263 ! positive regulation of canonical Wnt signaling pathway +is_a: GO:2000079 ! regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +relationship: positively_regulates GO:0044343 ! canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation +created_by: tb +creation_date: 2010-08-27T11:23:00Z + +[Term] +id: GO:2000082 +name: regulation of L-ascorbic acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process." [PMID:19395407] +synonym: "regulation of ascorbate biosynthesis" EXACT [GOC:obol] +synonym: "regulation of ascorbate biosynthetic process" EXACT [GOC:obol] +synonym: "regulation of L-ascorbic acid anabolism" EXACT [GOC:obol] +synonym: "regulation of L-ascorbic acid biosynthesis" EXACT [GOC:obol] +synonym: "regulation of L-ascorbic acid formation" EXACT [GOC:obol] +synonym: "regulation of L-ascorbic acid synthesis" EXACT [GOC:obol] +synonym: "regulation of vitamin C biosynthesis" EXACT [GOC:obol] +synonym: "regulation of vitamin C biosynthetic process" EXACT [GOC:obol] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0030656 ! regulation of vitamin metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019853 ! L-ascorbic acid biosynthetic process +relationship: regulates GO:0019853 ! L-ascorbic acid biosynthetic process +created_by: tb +creation_date: 2010-08-27T11:26:16Z + +[Term] +id: GO:2000083 +name: negative regulation of L-ascorbic acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process." [PMID:19395407] +synonym: "negative regulation of ascorbate biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of ascorbate biosynthetic process" EXACT [GOC:obol] +synonym: "negative regulation of L-ascorbic acid anabolism" EXACT [GOC:obol] +synonym: "negative regulation of L-ascorbic acid biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of L-ascorbic acid formation" EXACT [GOC:obol] +synonym: "negative regulation of L-ascorbic acid synthesis" EXACT [GOC:obol] +synonym: "negative regulation of vitamin C biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of vitamin C biosynthetic process" EXACT [GOC:obol] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:0046137 ! negative regulation of vitamin metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:2000082 ! regulation of L-ascorbic acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019853 ! L-ascorbic acid biosynthetic process +relationship: negatively_regulates GO:0019853 ! L-ascorbic acid biosynthetic process +created_by: tb +creation_date: 2010-08-27T11:26:19Z + +[Term] +id: GO:2000084 +name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] +synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +relationship: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +created_by: dph +creation_date: 2010-09-03T06:06:41Z + +[Term] +id: GO:2000085 +name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] +synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis +is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +relationship: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +created_by: dph +creation_date: 2010-09-03T06:08:21Z + +[Term] +id: GO:2000086 +name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] +synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis +is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +relationship: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis +created_by: dph +creation_date: 2010-09-03T06:08:24Z + +[Term] +id: GO:2000087 +name: regulation of mesonephric glomerulus development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesonephric glomerulus development." [GOC:mtg_kidney_jan10] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0090192 ! regulation of glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061224 ! mesonephric glomerulus development +relationship: regulates GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-09-03T06:09:19Z + +[Term] +id: GO:2000088 +name: negative regulation of mesonephric glomerulus development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development." [GOC:mtg_kidney_jan10] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0090194 ! negative regulation of glomerulus development +is_a: GO:2000087 ! regulation of mesonephric glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061224 ! mesonephric glomerulus development +relationship: negatively_regulates GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-09-03T06:09:22Z + +[Term] +id: GO:2000089 +name: positive regulation of mesonephric glomerulus development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development." [GOC:mtg_kidney_jan10] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0090193 ! positive regulation of glomerulus development +is_a: GO:2000087 ! regulation of mesonephric glomerulus development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061224 ! mesonephric glomerulus development +relationship: positively_regulates GO:0061224 ! mesonephric glomerulus development +created_by: dph +creation_date: 2010-09-03T06:09:24Z + +[Term] +id: GO:2000090 +name: regulation of mesonephric glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072124 ! regulation of glomerular mesangial cell proliferation +is_a: GO:2000087 ! regulation of mesonephric glomerulus development +is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +relationship: regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +created_by: dph +creation_date: 2010-09-03T06:10:28Z + +[Term] +id: GO:2000091 +name: negative regulation of mesonephric glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072125 ! negative regulation of glomerular mesangial cell proliferation +is_a: GO:2000088 ! negative regulation of mesonephric glomerulus development +is_a: GO:2000090 ! regulation of mesonephric glomerular mesangial cell proliferation +is_a: GO:2000607 ! negative regulation of cell proliferation involved in mesonephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +relationship: negatively_regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +created_by: dph +creation_date: 2010-09-03T06:10:31Z + +[Term] +id: GO:2000092 +name: positive regulation of mesonephric glomerular mesangial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation." [GOC:mtg_kidney_jan10] +is_a: GO:0072126 ! positive regulation of glomerular mesangial cell proliferation +is_a: GO:2000089 ! positive regulation of mesonephric glomerulus development +is_a: GO:2000090 ! regulation of mesonephric glomerular mesangial cell proliferation +is_a: GO:2000608 ! positive regulation of cell proliferation involved in mesonephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +relationship: positively_regulates GO:0061269 ! mesonephric glomerular mesangial cell proliferation involved in mesonephros development +created_by: dph +creation_date: 2010-09-03T06:10:33Z + +[Term] +id: GO:2000093 +name: regulation of mesonephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061265 ! mesonephric nephron tubule epithelial cell differentiation +relationship: regulates GO:0061265 ! mesonephric nephron tubule epithelial cell differentiation +created_by: dph +creation_date: 2010-09-03T06:12:25Z + +[Term] +id: GO:2000094 +name: negative regulation of mesonephric nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation +is_a: GO:2000093 ! regulation of mesonephric nephron tubule epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061265 ! mesonephric nephron tubule epithelial cell differentiation +relationship: negatively_regulates GO:0061265 ! mesonephric nephron tubule epithelial cell differentiation +created_by: dph +creation_date: 2010-09-03T06:12:28Z + +[Term] +id: GO:2000095 +name: regulation of Wnt signaling pathway, planar cell polarity pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway." [GOC:BHF] +synonym: "regulation of non-canonical Wnt signaling pathway" RELATED [GOC:obol] +synonym: "regulation of PCP pathway" EXACT [GOC:obol] +synonym: "regulation of Wnt receptor signaling pathway, planar cell polarity pathway" EXACT [] +synonym: "regulation of Wnt receptor signalling pathway, planar cell polarity pathway" EXACT [GOC:obol] +synonym: "regulation of Wnt-activated signaling pathway, planar cell polarity pathway" EXACT [GOC:signaling] +synonym: "regulation of Wnt-JNK signaling pathway" RELATED [GOC:obol] +synonym: "regulation of Wnt-PCP signaling pathway" RELATED [GOC:obol] +is_a: GO:0090175 ! regulation of establishment of planar polarity +is_a: GO:2000050 ! regulation of non-canonical Wnt signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +relationship: regulates GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +created_by: jl +creation_date: 2010-09-08T01:07:39Z + +[Term] +id: GO:2000096 +name: positive regulation of Wnt signaling pathway, planar cell polarity pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway." [GOC:BHF] +synonym: "positive regulation of non-canonical Wnt signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of PCP pathway" EXACT [GOC:obol] +synonym: "positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway" EXACT [] +synonym: "positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway" EXACT [GOC:obol] +synonym: "positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway" EXACT [GOC:signaling] +synonym: "positive regulation of Wnt-JNK signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of Wnt-PCP signaling pathway" RELATED [GOC:obol] +is_a: GO:2000052 ! positive regulation of non-canonical Wnt signaling pathway +is_a: GO:2000095 ! regulation of Wnt signaling pathway, planar cell polarity pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +relationship: positively_regulates GO:0060071 ! Wnt signaling pathway, planar cell polarity pathway +created_by: jl +creation_date: 2010-09-08T01:07:42Z + +[Term] +id: GO:2000097 +name: regulation of smooth muscle cell-matrix adhesion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion." [GOC:BHF] +is_a: GO:0001952 ! regulation of cell-matrix adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061302 ! smooth muscle cell-matrix adhesion +relationship: regulates GO:0061302 ! smooth muscle cell-matrix adhesion +property_value: RO:0002161 NCBITaxon:4751 +created_by: dph +creation_date: 2010-09-14T04:22:20Z + +[Term] +id: GO:2000098 +name: negative regulation of smooth muscle cell-matrix adhesion +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion." [GOC:BHF] +is_a: GO:0001953 ! negative regulation of cell-matrix adhesion +is_a: GO:2000097 ! regulation of smooth muscle cell-matrix adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061302 ! smooth muscle cell-matrix adhesion +relationship: negatively_regulates GO:0061302 ! smooth muscle cell-matrix adhesion +created_by: dph +creation_date: 2010-09-14T04:22:22Z + +[Term] +id: GO:2000099 +name: regulation of establishment or maintenance of bipolar cell polarity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity." [GOC:obol] +is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061245 ! establishment or maintenance of bipolar cell polarity +relationship: regulates GO:0061245 ! establishment or maintenance of bipolar cell polarity +created_by: dph +creation_date: 2010-09-14T04:40:51Z + +[Term] +id: GO:2000100 +name: regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape." [GOC:obol] +is_a: GO:2000099 ! regulation of establishment or maintenance of bipolar cell polarity +is_a: GO:2000769 ! regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +relationship: regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-09-14T04:44:57Z + +[Term] +id: GO:2000101 +name: regulation of mammary stem cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mammary stem cell proliferation." [GOC:obol] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002174 ! mammary stem cell proliferation +relationship: regulates GO:0002174 ! mammary stem cell proliferation +created_by: dph +creation_date: 2010-09-14T06:10:32Z + +[Term] +id: GO:2000102 +name: negative regulation of mammary stem cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation." [GOC:obol] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000101 ! regulation of mammary stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002174 ! mammary stem cell proliferation +relationship: negatively_regulates GO:0002174 ! mammary stem cell proliferation +created_by: dph +creation_date: 2010-09-14T06:10:34Z + +[Term] +id: GO:2000103 +name: positive regulation of mammary stem cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation." [GOC:obol] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000101 ! regulation of mammary stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002174 ! mammary stem cell proliferation +relationship: positively_regulates GO:0002174 ! mammary stem cell proliferation +created_by: dph +creation_date: 2010-09-14T06:10:36Z + +[Term] +id: GO:2000104 +name: negative regulation of DNA-dependent DNA replication +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication." [GOC:mah] +is_a: GO:0008156 ! negative regulation of DNA replication +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006261 ! DNA-dependent DNA replication +relationship: negatively_regulates GO:0006261 ! DNA-dependent DNA replication +created_by: mah +creation_date: 2010-09-15T01:37:05Z + +[Term] +id: GO:2000105 +name: positive regulation of DNA-dependent DNA replication +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication." [GOC:mah] +is_a: GO:0045740 ! positive regulation of DNA replication +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006261 ! DNA-dependent DNA replication +relationship: positively_regulates GO:0006261 ! DNA-dependent DNA replication +created_by: mah +creation_date: 2010-09-15T01:37:10Z + +[Term] +id: GO:2000106 +name: regulation of leukocyte apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "regulation of leukocyte apoptosis" NARROW [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071887 ! leukocyte apoptotic process +relationship: regulates GO:0071887 ! leukocyte apoptotic process +created_by: mah +creation_date: 2010-09-15T01:42:05Z + +[Term] +id: GO:2000107 +name: negative regulation of leukocyte apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "negative regulation of leukocyte apoptosis" NARROW [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071887 ! leukocyte apoptotic process +relationship: negatively_regulates GO:0071887 ! leukocyte apoptotic process +created_by: mah +creation_date: 2010-09-15T01:42:09Z + +[Term] +id: GO:2000108 +name: positive regulation of leukocyte apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "positive regulation of leukocyte apoptosis" NARROW [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071887 ! leukocyte apoptotic process +relationship: positively_regulates GO:0071887 ! leukocyte apoptotic process +created_by: mah +creation_date: 2010-09-15T01:42:12Z + +[Term] +id: GO:2000109 +name: regulation of macrophage apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "regulation of activation-induced cell death" RELATED [GOC:yaf] +synonym: "regulation of AICD" RELATED [GOC:yaf] +synonym: "regulation of macrophage apoptosis" NARROW [] +is_a: GO:0033032 ! regulation of myeloid cell apoptotic process +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071888 ! macrophage apoptotic process +relationship: regulates GO:0071888 ! macrophage apoptotic process +created_by: mah +creation_date: 2010-09-15T01:44:15Z + +[Term] +id: GO:2000110 +name: negative regulation of macrophage apoptotic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "negative regulation of activation-induced cell death" RELATED [GOC:yaf] +synonym: "negative regulation of AICD" RELATED [GOC:yaf] +synonym: "negative regulation of macrophage apoptosis" NARROW [] +is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process +is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process +is_a: GO:2000109 ! regulation of macrophage apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071888 ! macrophage apoptotic process +relationship: negatively_regulates GO:0071888 ! macrophage apoptotic process +created_by: mah +creation_date: 2010-09-15T01:44:18Z + +[Term] +id: GO:2000111 +name: positive regulation of macrophage apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] +synonym: "positive regulation of activation-induced cell death" RELATED [GOC:yaf] +synonym: "positive regulation of AICD" RELATED [GOC:yaf] +synonym: "positive regulation of macrophage apoptosis" NARROW [] +is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process +is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process +is_a: GO:2000109 ! regulation of macrophage apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071888 ! macrophage apoptotic process +relationship: positively_regulates GO:0071888 ! macrophage apoptotic process +created_by: mah +creation_date: 2010-09-15T01:44:21Z + +[Term] +id: GO:2000112 +name: regulation of cellular macromolecule biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] +synonym: "regulation of cellular biopolymer biosynthetic process" EXACT [GOC:obol] +synonym: "regulation of cellular macromolecule anabolism" EXACT [GOC:obol] +synonym: "regulation of cellular macromolecule biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellular macromolecule formation" EXACT [GOC:obol] +synonym: "regulation of cellular macromolecule synthesis" EXACT [GOC:obol] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034645 ! cellular macromolecule biosynthetic process +relationship: regulates GO:0034645 ! cellular macromolecule biosynthetic process +created_by: tb +creation_date: 2010-09-15T08:55:45Z + +[Term] +id: GO:2000113 +name: negative regulation of cellular macromolecule biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process." [GOC:obol] +synonym: "negative regulation of cellular biopolymer biosynthetic process" EXACT [GOC:obol] +synonym: "negative regulation of cellular macromolecule anabolism" EXACT [GOC:obol] +synonym: "negative regulation of cellular macromolecule biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellular macromolecule formation" EXACT [GOC:obol] +synonym: "negative regulation of cellular macromolecule synthesis" EXACT [GOC:obol] +is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034645 ! cellular macromolecule biosynthetic process +relationship: negatively_regulates GO:0034645 ! cellular macromolecule biosynthetic process +created_by: tb +creation_date: 2010-09-15T08:55:48Z + +[Term] +id: GO:2000114 +name: regulation of establishment of cell polarity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph] +synonym: "regulation of bud site selection/establishment of cell polarity" RELATED [GOC:obol] +synonym: "regulation of cell polarization" EXACT [GOC:obol] +is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030010 ! establishment of cell polarity +relationship: regulates GO:0030010 ! establishment of cell polarity +created_by: dph +creation_date: 2010-09-16T01:22:36Z + +[Term] +id: GO:2000115 +name: regulation of maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape." [GOC:obol] +is_a: GO:2000100 ! regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061305 ! maintenance of bipolar cell polarity regulating cell shape +relationship: regulates GO:0061305 ! maintenance of bipolar cell polarity regulating cell shape +created_by: dph +creation_date: 2010-09-21T06:33:26Z + +[Term] +id: GO:2000116 +name: regulation of cysteine-type endopeptidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity." [GOC:obol, GOC:yaf] +synonym: "regulation of lysosomal cysteine-type endopeptidase" RELATED [GOC:obol] +synonym: "regulation of thiol endopeptidase activity" EXACT [GOC:obol] +is_a: GO:0052548 ! regulation of endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004197 ! cysteine-type endopeptidase activity +relationship: regulates GO:0004197 ! cysteine-type endopeptidase activity +created_by: jl +creation_date: 2010-09-23T10:24:33Z + +[Term] +id: GO:2000117 +name: negative regulation of cysteine-type endopeptidase activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity." [GOC:obol, GOC:yaf] +synonym: "negative regulation of lysosomal cysteine-type endopeptidase" RELATED [GOC:obol] +synonym: "negative regulation of thiol endopeptidase activity" EXACT [GOC:obol] +is_a: GO:0010951 ! negative regulation of endopeptidase activity +is_a: GO:2000116 ! regulation of cysteine-type endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004197 ! cysteine-type endopeptidase activity +relationship: negatively_regulates GO:0004197 ! cysteine-type endopeptidase activity +created_by: jl +creation_date: 2010-09-23T10:24:35Z + +[Term] +id: GO:2000118 +name: regulation of sodium-dependent phosphate transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport." [GOC:BHF] +is_a: GO:0010966 ! regulation of phosphate transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044341 ! sodium-dependent phosphate transport +relationship: regulates GO:0044341 ! sodium-dependent phosphate transport +created_by: jl +creation_date: 2010-09-23T01:34:59Z + +[Term] +id: GO:2000119 +name: negative regulation of sodium-dependent phosphate transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport." [GOC:BHF] +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:2000118 ! regulation of sodium-dependent phosphate transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044341 ! sodium-dependent phosphate transport +relationship: negatively_regulates GO:0044341 ! sodium-dependent phosphate transport +created_by: jl +creation_date: 2010-09-23T01:35:03Z + +[Term] +id: GO:2000120 +name: positive regulation of sodium-dependent phosphate transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport." [GOC:BHF] +is_a: GO:1903793 ! positive regulation of anion transport +is_a: GO:2000118 ! regulation of sodium-dependent phosphate transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044341 ! sodium-dependent phosphate transport +relationship: positively_regulates GO:0044341 ! sodium-dependent phosphate transport +created_by: jl +creation_date: 2010-09-23T01:35:06Z + +[Term] +id: GO:2000121 +name: regulation of removal of superoxide radicals +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of removal of superoxide radicals." [GOC:obol] +synonym: "regulation of removal of O2-" EXACT [GOC:obol] +synonym: "regulation of removal of oxygen free radicals" EXACT [GOC:obol] +is_a: GO:0090322 ! regulation of superoxide metabolic process +is_a: GO:1900407 ! regulation of cellular response to oxidative stress +is_a: GO:1901031 ! regulation of response to reactive oxygen species +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019430 ! removal of superoxide radicals +relationship: regulates GO:0019430 ! removal of superoxide radicals +created_by: dhl +creation_date: 2010-09-27T05:30:37Z + +[Term] +id: GO:2000122 +name: negative regulation of stomatal complex development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development." [GOC:obol] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:2000038 ! regulation of stomatal complex development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010374 ! stomatal complex development +relationship: negatively_regulates GO:0010374 ! stomatal complex development +created_by: dhl +creation_date: 2010-09-27T08:28:26Z + +[Term] +id: GO:2000123 +name: positive regulation of stomatal complex development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stomatal complex development." [GOC:obol] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:2000038 ! regulation of stomatal complex development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010374 ! stomatal complex development +relationship: positively_regulates GO:0010374 ! stomatal complex development +created_by: dhl +creation_date: 2010-09-27T08:28:28Z + +[Term] +id: GO:2000124 +name: regulation of endocannabinoid signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway." [GOC:mah, PMID:15550444] +synonym: "regulation of endocannabinoid signalling pathway" EXACT [GOC:obol] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071926 ! endocannabinoid signaling pathway +relationship: regulates GO:0071926 ! endocannabinoid signaling pathway +created_by: mah +creation_date: 2010-09-29T09:05:43Z + +[Term] +id: GO:2000125 +name: regulation of octopamine or tyramine signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway." [GOC:mah] +synonym: "regulation of octopamine or tyramine signalling pathway" EXACT [GOC:obol] +synonym: "regulation of octopamine/tyramine signaling pathway" EXACT [GOC:obol] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007211 ! octopamine or tyramine signaling pathway +relationship: regulates GO:0007211 ! octopamine or tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:27:12Z + +[Term] +id: GO:2000126 +name: negative regulation of octopamine or tyramine signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway." [GOC:mah] +synonym: "negative regulation of octopamine or tyramine signalling pathway" EXACT [GOC:obol] +synonym: "negative regulation of octopamine/tyramine signaling pathway" EXACT [GOC:obol] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:2000125 ! regulation of octopamine or tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007211 ! octopamine or tyramine signaling pathway +relationship: negatively_regulates GO:0007211 ! octopamine or tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:27:16Z + +[Term] +id: GO:2000127 +name: positive regulation of octopamine or tyramine signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway." [GOC:mah] +synonym: "positive regulation of octopamine or tyramine signalling pathway" EXACT [GOC:obol] +synonym: "positive regulation of octopamine/tyramine signaling pathway" EXACT [GOC:obol] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:2000125 ! regulation of octopamine or tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007211 ! octopamine or tyramine signaling pathway +relationship: positively_regulates GO:0007211 ! octopamine or tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:27:19Z + +[Term] +id: GO:2000128 +name: regulation of octopamine signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of octopamine signaling pathway." [GOC:mah] +synonym: "regulation of octopamine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000125 ! regulation of octopamine or tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071927 ! octopamine signaling pathway +relationship: regulates GO:0071927 ! octopamine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:29:41Z + +[Term] +id: GO:2000129 +name: negative regulation of octopamine signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway." [GOC:mah] +synonym: "negative regulation of octopamine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000126 ! negative regulation of octopamine or tyramine signaling pathway +is_a: GO:2000128 ! regulation of octopamine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071927 ! octopamine signaling pathway +relationship: negatively_regulates GO:0071927 ! octopamine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:29:44Z + +[Term] +id: GO:2000130 +name: positive regulation of octopamine signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway." [GOC:mah] +synonym: "positive regulation of octopamine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000127 ! positive regulation of octopamine or tyramine signaling pathway +is_a: GO:2000128 ! regulation of octopamine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071927 ! octopamine signaling pathway +relationship: positively_regulates GO:0071927 ! octopamine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:29:47Z + +[Term] +id: GO:2000131 +name: regulation of tyramine signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tyramine signaling pathway." [GOC:mah] +synonym: "regulation of tyramine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000125 ! regulation of octopamine or tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071928 ! tyramine signaling pathway +relationship: regulates GO:0071928 ! tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:31:56Z + +[Term] +id: GO:2000132 +name: negative regulation of tyramine signaling pathway +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway." [GOC:mah] +synonym: "negative regulation of tyramine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000126 ! negative regulation of octopamine or tyramine signaling pathway +is_a: GO:2000131 ! regulation of tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071928 ! tyramine signaling pathway +relationship: negatively_regulates GO:0071928 ! tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:32:00Z + +[Term] +id: GO:2000133 +name: positive regulation of tyramine signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway." [GOC:mah] +synonym: "positive regulation of tyramine signalling pathway" EXACT [GOC:obol] +is_a: GO:2000127 ! positive regulation of octopamine or tyramine signaling pathway +is_a: GO:2000131 ! regulation of tyramine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071928 ! tyramine signaling pathway +relationship: positively_regulates GO:0071928 ! tyramine signaling pathway +created_by: mah +creation_date: 2010-09-29T09:32:03Z + +[Term] +id: GO:2000134 +name: negative regulation of G1/S transition of mitotic cell cycle +namespace: biological_process +def: "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] +is_a: GO:1901991 ! negative regulation of mitotic cell cycle phase transition +is_a: GO:1902807 ! negative regulation of cell cycle G1/S phase transition +is_a: GO:2000045 ! regulation of G1/S transition of mitotic cell cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle +relationship: negatively_regulates GO:0000082 ! G1/S transition of mitotic cell cycle +created_by: mah +creation_date: 2010-09-29T09:38:51Z + +[Term] +id: GO:2000135 +name: obsolete positive regulation of regulation of secondary heart field cardioblast proliferation +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation." [GOC:dph] +comment: This term was made obsolete because it makes no sense and was added in error. +synonym: "positive regulation of regulation of second heart field cardioblast proliferation" EXACT [GOC:obol] +synonym: "positive regulation of regulation of secondary heart field cardioblast proliferation" EXACT [] +is_obsolete: true +created_by: dph +creation_date: 2010-09-29T12:40:37Z + +[Term] +id: GO:2000136 +name: regulation of cell proliferation involved in heart morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +relationship: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +created_by: dph +creation_date: 2010-09-29T12:43:53Z + +[Term] +id: GO:2000137 +name: negative regulation of cell proliferation involved in heart morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +relationship: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +created_by: dph +creation_date: 2010-09-29T12:43:55Z + +[Term] +id: GO:2000138 +name: positive regulation of cell proliferation involved in heart morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +relationship: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis +created_by: dph +creation_date: 2010-09-29T12:43:57Z + +[Term] +id: GO:2000139 +name: regulation of octopamine signaling pathway involved in response to food +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300] +synonym: "regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah] +is_a: GO:0032095 ! regulation of response to food +is_a: GO:2000128 ! regulation of octopamine signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071935 ! octopamine signaling pathway involved in response to food +relationship: regulates GO:0071935 ! octopamine signaling pathway involved in response to food +created_by: mah +creation_date: 2010-09-30T02:48:07Z + +[Term] +id: GO:2000140 +name: negative regulation of octopamine signaling pathway involved in response to food +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300] +synonym: "negative regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah] +is_a: GO:0032096 ! negative regulation of response to food +is_a: GO:2000129 ! negative regulation of octopamine signaling pathway +is_a: GO:2000139 ! regulation of octopamine signaling pathway involved in response to food +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food +relationship: negatively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food +created_by: mah +creation_date: 2010-09-30T02:48:10Z + +[Term] +id: GO:2000141 +name: positive regulation of octopamine signaling pathway involved in response to food +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food." [GOC:mah, PMID:19609300] +synonym: "positive regulation of octopamine signalling pathway involved in response to food" EXACT [GOC:mah] +is_a: GO:0032097 ! positive regulation of response to food +is_a: GO:2000130 ! positive regulation of octopamine signaling pathway +is_a: GO:2000139 ! regulation of octopamine signaling pathway involved in response to food +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food +relationship: positively_regulates GO:0071935 ! octopamine signaling pathway involved in response to food +created_by: mah +creation_date: 2010-09-30T02:48:12Z + +[Term] +id: GO:2000142 +name: regulation of DNA-templated transcription, initiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation." [GOC:mah, GOC:txnOH] +synonym: "regulation of DNA-dependent transcription, initiation" EXACT [GOC:txnOH] +synonym: "regulation of initiation of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "regulation of transcription initiation, DNA-dependent" EXACT [GOC:jh2] +is_a: GO:0006355 ! regulation of transcription, DNA-templated +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006352 ! DNA-templated transcription, initiation +relationship: regulates GO:0006352 ! DNA-templated transcription, initiation +created_by: mah +creation_date: 2010-10-01T09:11:35Z + +[Term] +id: GO:2000143 +name: negative regulation of DNA-templated transcription, initiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation." [GOC:mah, GOC:txnOH] +synonym: "negative regulation of DNA-dependent transcription, initiation" EXACT [GOC:txnOH] +synonym: "negative regulation of initiation of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "negative regulation of transcription initiation, DNA-dependent" EXACT [GOC:jh2] +is_a: GO:0045892 ! negative regulation of transcription, DNA-templated +is_a: GO:2000142 ! regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006352 ! DNA-templated transcription, initiation +relationship: negatively_regulates GO:0006352 ! DNA-templated transcription, initiation +created_by: mah +creation_date: 2010-10-01T09:11:40Z + +[Term] +id: GO:2000144 +name: positive regulation of DNA-templated transcription, initiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation." [GOC:mah, GOC:txnOH] +synonym: "positive regulation of DNA-dependent transcription, initiation" EXACT [GOC:txnOH] +synonym: "positive regulation of initiation of DNA-dependent transcription" EXACT [GOC:jh2] +synonym: "positive regulation of transcription initiation, DNA-dependent" EXACT [GOC:jh2] +synonym: "transactivation" RELATED [PMID:11158542] +synonym: "transcriptional transactivation" RELATED [PMID:11580863] +is_a: GO:0045893 ! positive regulation of transcription, DNA-templated +is_a: GO:2000142 ! regulation of DNA-templated transcription, initiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006352 ! DNA-templated transcription, initiation +relationship: positively_regulates GO:0006352 ! DNA-templated transcription, initiation +created_by: mah +creation_date: 2010-10-01T09:11:43Z + +[Term] +id: GO:2000145 +name: regulation of cell motility +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah] +synonym: "regulation of cell locomotion" EXACT [GOC:obol] +synonym: "regulation of cell movement" RELATED [GOC:obol] +synonym: "regulation of movement of a cell" EXACT [GOC:obol] +is_a: GO:0040012 ! regulation of locomotion +is_a: GO:0051270 ! regulation of cellular component movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048870 ! cell motility +relationship: regulates GO:0048870 ! cell motility +created_by: mah +creation_date: 2010-10-01T09:41:21Z + +[Term] +id: GO:2000146 +name: negative regulation of cell motility +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah] +synonym: "negative regulation of cell locomotion" EXACT [GOC:obol] +synonym: "negative regulation of cell movement" RELATED [GOC:obol] +synonym: "negative regulation of movement of a cell" EXACT [GOC:obol] +is_a: GO:0040013 ! negative regulation of locomotion +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048870 ! cell motility +relationship: negatively_regulates GO:0048870 ! cell motility +created_by: mah +creation_date: 2010-10-01T09:41:26Z + +[Term] +id: GO:2000147 +name: positive regulation of cell motility +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah] +synonym: "positive regulation of cell locomotion" EXACT [GOC:obol] +synonym: "positive regulation of cell movement" RELATED [GOC:obol] +synonym: "positive regulation of movement of a cell" EXACT [GOC:obol] +is_a: GO:0040017 ! positive regulation of locomotion +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:2000145 ! regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048870 ! cell motility +relationship: positively_regulates GO:0048870 ! cell motility +created_by: mah +creation_date: 2010-10-01T09:41:30Z + +[Term] +id: GO:2000148 +name: regulation of planar cell polarity pathway involved in ventricular septum morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis." [GOC:dph] +is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis +is_a: GO:1904412 ! regulation of cardiac ventricle development +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061348 ! planar cell polarity pathway involved in ventricular septum morphogenesis +relationship: regulates GO:0061348 ! planar cell polarity pathway involved in ventricular septum morphogenesis +created_by: dph +creation_date: 2010-10-01T07:09:49Z + +[Term] +id: GO:2000149 +name: negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis." [GOC:dph] +is_a: GO:1901220 ! negative regulation of cardiac chamber morphogenesis +is_a: GO:1904413 ! negative regulation of cardiac ventricle development +is_a: GO:2000148 ! regulation of planar cell polarity pathway involved in ventricular septum morphogenesis +is_a: GO:2000160 ! negative regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061348 ! planar cell polarity pathway involved in ventricular septum morphogenesis +relationship: negatively_regulates GO:0061348 ! planar cell polarity pathway involved in ventricular septum morphogenesis +created_by: dph +creation_date: 2010-10-01T07:09:53Z + +[Term] +id: GO:2000150 +name: regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis." [GOC:dph] +is_a: GO:0055024 ! regulation of cardiac muscle tissue development +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061350 ! planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +relationship: regulates GO:0061350 ! planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +created_by: dph +creation_date: 2010-10-01T07:11:11Z + +[Term] +id: GO:2000151 +name: negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis." [GOC:dph] +is_a: GO:0055026 ! negative regulation of cardiac muscle tissue development +is_a: GO:2000150 ! regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +is_a: GO:2000160 ! negative regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061350 ! planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +relationship: negatively_regulates GO:0061350 ! planar cell polarity pathway involved in cardiac muscle tissue morphogenesis +created_by: dph +creation_date: 2010-10-01T07:11:15Z + +[Term] +id: GO:2000152 +name: regulation of ubiquitin-specific protease activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity." [GOC:obol] +synonym: "regulation of deubiquitinase activity" EXACT [] +synonym: "regulation of UBP" RELATED [GOC:obol] +synonym: "regulation of UCH2" RELATED [GOC:obol] +is_a: GO:0052547 ! regulation of peptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +relationship: regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +created_by: tb +creation_date: 2010-10-01T10:09:28Z + +[Term] +id: GO:2000153 +name: obsolete regulation of flagellar cell motility +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility." [GOC:mah] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "regulation of flagellar cell motility" EXACT [] +is_obsolete: true +consider: GO:1902019 +consider: GO:1902021 +created_by: mah +creation_date: 2010-10-04T12:41:02Z + +[Term] +id: GO:2000154 +name: obsolete negative regulation of flagellar cell motility +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility." [GOC:mah] +comment: This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest. +synonym: "negative regulation of flagellar cell motility" EXACT [] +is_obsolete: true +consider: GO:1902020 +consider: GO:1902201 +created_by: mah +creation_date: 2010-10-04T12:41:04Z + +[Term] +id: GO:2000155 +name: positive regulation of cilium-dependent cell motility +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl] +synonym: "positive regulation of ciliary cell motility" RELATED [] +is_a: GO:1902019 ! regulation of cilium-dependent cell motility +is_a: GO:2000147 ! positive regulation of cell motility +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060285 ! cilium-dependent cell motility +relationship: positively_regulates GO:0060285 ! cilium-dependent cell motility +created_by: mah +creation_date: 2010-10-04T12:41:05Z + +[Term] +id: GO:2000156 +name: regulation of retrograde vesicle-mediated transport, Golgi to ER +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER." [GOC:mah] +synonym: "regulation of cis-Golgi to rough endoplasmic reticulum transport" EXACT [GOC:obol] +synonym: "regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport" EXACT [GOC:obol] +synonym: "regulation of cis-Golgi to rough ER transport" EXACT [GOC:obol] +synonym: "regulation of cis-Golgi to rough ER vesicle-mediated transport" EXACT [GOC:obol] +synonym: "regulation of retrograde (Golgi to ER) transport" EXACT [GOC:obol] +synonym: "regulation of retrograde transport, Golgi to endoplasmic reticulum" EXACT [GOC:obol] +synonym: "regulation of retrograde transport, Golgi to ER" EXACT [GOC:obol] +synonym: "regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum" RELATED [GOC:obol] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006890 ! retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +relationship: regulates GO:0006890 ! retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum +created_by: mah +creation_date: 2010-10-04T12:46:35Z + +[Term] +id: GO:2000157 +name: negative regulation of ubiquitin-specific protease activity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity." [GOC:obol] +synonym: "negative regulation of deubiquitinase activity" EXACT [] +synonym: "negative regulation of ubiquitin hydrolase activity" EXACT [GOC:obol] +synonym: "negative regulation of UBP" RELATED [GOC:obol] +synonym: "negative regulation of UCH2" RELATED [GOC:obol] +is_a: GO:0010466 ! negative regulation of peptidase activity +is_a: GO:2000152 ! regulation of ubiquitin-specific protease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +relationship: negatively_regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +created_by: tb +creation_date: 2010-10-04T10:42:27Z + +[Term] +id: GO:2000158 +name: positive regulation of ubiquitin-specific protease activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity." [GOC:obol] +synonym: "positive regulation of deubiquitinase activity" EXACT [] +synonym: "positive regulation of ubiquitin hydrolase activity" EXACT [GOC:obol] +synonym: "positive regulation of UBP" RELATED [GOC:obol] +synonym: "positive regulation of UCH2" RELATED [GOC:obol] +is_a: GO:0010952 ! positive regulation of peptidase activity +is_a: GO:2000152 ! regulation of ubiquitin-specific protease activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +relationship: positively_regulates GO:0004843 ! thiol-dependent ubiquitin-specific protease activity +created_by: tb +creation_date: 2010-10-04T10:42:29Z + +[Term] +id: GO:2000159 +name: regulation of planar cell polarity pathway involved in heart morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis." [GOC:dph] +is_a: GO:0003307 ! regulation of Wnt signaling pathway involved in heart development +is_a: GO:2000095 ! regulation of Wnt signaling pathway, planar cell polarity pathway +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: regulates GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +created_by: dph +creation_date: 2010-10-05T01:03:22Z + +[Term] +id: GO:2000160 +name: negative regulation of planar cell polarity pathway involved in heart morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis." [GOC:dph] +is_a: GO:0003308 ! negative regulation of Wnt signaling pathway involved in heart development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000051 ! negative regulation of non-canonical Wnt signaling pathway +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +relationship: negatively_regulates GO:0061346 ! planar cell polarity pathway involved in heart morphogenesis +created_by: dph +creation_date: 2010-10-05T01:03:25Z + +[Term] +id: GO:2000161 +name: regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis." [GOC:dph] +is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061349 ! planar cell polarity pathway involved in cardiac right atrium morphogenesis +relationship: regulates GO:0061349 ! planar cell polarity pathway involved in cardiac right atrium morphogenesis +created_by: dph +creation_date: 2010-10-05T01:05:21Z + +[Term] +id: GO:2000162 +name: negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis." [GOC:dph] +is_a: GO:1901220 ! negative regulation of cardiac chamber morphogenesis +is_a: GO:2000160 ! negative regulation of planar cell polarity pathway involved in heart morphogenesis +is_a: GO:2000161 ! regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061349 ! planar cell polarity pathway involved in cardiac right atrium morphogenesis +relationship: negatively_regulates GO:0061349 ! planar cell polarity pathway involved in cardiac right atrium morphogenesis +created_by: dph +creation_date: 2010-10-05T01:05:24Z + +[Term] +id: GO:2000163 +name: regulation of planar cell polarity pathway involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis." [GOC:dph] +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061347 ! planar cell polarity pathway involved in outflow tract morphogenesis +relationship: regulates GO:0061347 ! planar cell polarity pathway involved in outflow tract morphogenesis +created_by: dph +creation_date: 2010-10-05T01:06:13Z + +[Term] +id: GO:2000164 +name: negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis." [GOC:dph] +is_a: GO:2000160 ! negative regulation of planar cell polarity pathway involved in heart morphogenesis +is_a: GO:2000163 ! regulation of planar cell polarity pathway involved in outflow tract morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061347 ! planar cell polarity pathway involved in outflow tract morphogenesis +relationship: negatively_regulates GO:0061347 ! planar cell polarity pathway involved in outflow tract morphogenesis +created_by: dph +creation_date: 2010-10-05T01:06:15Z + +[Term] +id: GO:2000165 +name: regulation of planar cell polarity pathway involved in pericardium morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis." [GOC:dph] +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:2000159 ! regulation of planar cell polarity pathway involved in heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061354 ! planar cell polarity pathway involved in pericardium morphogenesis +relationship: regulates GO:0061354 ! planar cell polarity pathway involved in pericardium morphogenesis +created_by: dph +creation_date: 2010-10-05T01:07:36Z + +[Term] +id: GO:2000166 +name: negative regulation of planar cell polarity pathway involved in pericardium morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis." [GOC:dph] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium +is_a: GO:2000160 ! negative regulation of planar cell polarity pathway involved in heart morphogenesis +is_a: GO:2000165 ! regulation of planar cell polarity pathway involved in pericardium morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061354 ! planar cell polarity pathway involved in pericardium morphogenesis +relationship: negatively_regulates GO:0061354 ! planar cell polarity pathway involved in pericardium morphogenesis +created_by: dph +creation_date: 2010-10-05T01:07:39Z + +[Term] +id: GO:2000167 +name: regulation of planar cell polarity pathway involved in neural tube closure +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure." [GOC:dph] +is_a: GO:0090178 ! regulation of establishment of planar polarity involved in neural tube closure +is_a: GO:2000095 ! regulation of Wnt signaling pathway, planar cell polarity pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090179 ! planar cell polarity pathway involved in neural tube closure +relationship: regulates GO:0090179 ! planar cell polarity pathway involved in neural tube closure +created_by: dph +creation_date: 2010-10-05T01:08:53Z + +[Term] +id: GO:2000168 +name: negative regulation of planar cell polarity pathway involved in neural tube closure +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure." [GOC:dph] +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:1905277 ! negative regulation of epithelial tube formation +is_a: GO:2000051 ! negative regulation of non-canonical Wnt signaling pathway +is_a: GO:2000167 ! regulation of planar cell polarity pathway involved in neural tube closure +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090179 ! planar cell polarity pathway involved in neural tube closure +relationship: negatively_regulates GO:0090179 ! planar cell polarity pathway involved in neural tube closure +created_by: dph +creation_date: 2010-10-05T01:08:56Z + +[Term] +id: GO:2000169 +name: regulation of peptidyl-cysteine S-nitrosylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:obol] +is_a: GO:0031399 ! regulation of protein modification process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +relationship: regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +created_by: rl +creation_date: 2010-10-07T10:49:32Z + +[Term] +id: GO:2000170 +name: positive regulation of peptidyl-cysteine S-nitrosylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:obol] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:2000169 ! regulation of peptidyl-cysteine S-nitrosylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +relationship: positively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation +created_by: rl +creation_date: 2010-10-07T10:49:35Z + +[Term] +id: GO:2000171 +name: negative regulation of dendrite development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development." [GOC:obol] +is_a: GO:0010977 ! negative regulation of neuron projection development +is_a: GO:0050773 ! regulation of dendrite development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016358 ! dendrite development +relationship: negatively_regulates GO:0016358 ! dendrite development +created_by: rl +creation_date: 2010-10-07T10:53:15Z + +[Term] +id: GO:2000172 +name: regulation of branching morphogenesis of a nerve +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] +is_a: GO:0051960 ! regulation of nervous system development +is_a: GO:0060688 ! regulation of morphogenesis of a branching structure +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048755 ! branching morphogenesis of a nerve +relationship: regulates GO:0048755 ! branching morphogenesis of a nerve +created_by: rl +creation_date: 2010-10-07T12:07:54Z + +[Term] +id: GO:2000173 +name: negative regulation of branching morphogenesis of a nerve +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve +relationship: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve +created_by: rl +creation_date: 2010-10-07T12:07:56Z + +[Term] +id: GO:2000174 +name: regulation of pro-T cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] +synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:0045580 ! regulation of T cell differentiation +is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002572 ! pro-T cell differentiation +relationship: regulates GO:0002572 ! pro-T cell differentiation +created_by: mah +creation_date: 2010-10-11T10:24:30Z + +[Term] +id: GO:2000175 +name: negative regulation of pro-T cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] +synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:0045581 ! negative regulation of T cell differentiation +is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation +is_a: GO:2000174 ! regulation of pro-T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002572 ! pro-T cell differentiation +relationship: negatively_regulates GO:0002572 ! pro-T cell differentiation +created_by: mah +creation_date: 2010-10-11T10:24:33Z + +[Term] +id: GO:2000176 +name: positive regulation of pro-T cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] +synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:0045582 ! positive regulation of T cell differentiation +is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation +is_a: GO:2000174 ! regulation of pro-T cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002572 ! pro-T cell differentiation +relationship: positively_regulates GO:0002572 ! pro-T cell differentiation +created_by: mah +creation_date: 2010-10-11T10:24:35Z + +[Term] +id: GO:2000177 +name: regulation of neural precursor cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061351 ! neural precursor cell proliferation +relationship: regulates GO:0061351 ! neural precursor cell proliferation +created_by: dph +creation_date: 2010-10-13T12:40:41Z + +[Term] +id: GO:2000178 +name: negative regulation of neural precursor cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061351 ! neural precursor cell proliferation +relationship: negatively_regulates GO:0061351 ! neural precursor cell proliferation +created_by: dph +creation_date: 2010-10-13T12:40:43Z + +[Term] +id: GO:2000179 +name: positive regulation of neural precursor cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:2000177 ! regulation of neural precursor cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061351 ! neural precursor cell proliferation +relationship: positively_regulates GO:0061351 ! neural precursor cell proliferation +created_by: dph +creation_date: 2010-10-13T12:40:45Z + +[Term] +id: GO:2000180 +name: negative regulation of androgen biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process." [GOC:dph, GOC:yaf] +synonym: "negative regulation of androgen anabolism" EXACT [GOC:obol] +synonym: "negative regulation of androgen biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of androgen formation" EXACT [GOC:obol] +synonym: "negative regulation of androgen synthesis" EXACT [GOC:obol] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006702 ! androgen biosynthetic process +relationship: negatively_regulates GO:0006702 ! androgen biosynthetic process +created_by: dph +creation_date: 2010-10-13T12:43:17Z + +[Term] +id: GO:2000181 +name: negative regulation of blood vessel morphogenesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:1901343 ! negative regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048514 ! blood vessel morphogenesis +relationship: negatively_regulates GO:0048514 ! blood vessel morphogenesis +created_by: dph +creation_date: 2010-10-13T12:46:31Z + +[Term] +id: GO:2000182 +name: regulation of progesterone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of progesterone biosynthetic process." [GOC:dph] +synonym: "regulation of progesterone anabolism" EXACT [GOC:obol] +synonym: "regulation of progesterone biosynthesis" EXACT [GOC:obol] +synonym: "regulation of progesterone formation" EXACT [GOC:obol] +synonym: "regulation of progesterone synthesis" EXACT [GOC:obol] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006701 ! progesterone biosynthetic process +relationship: regulates GO:0006701 ! progesterone biosynthetic process +created_by: dph +creation_date: 2010-10-14T07:36:06Z + +[Term] +id: GO:2000183 +name: negative regulation of progesterone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process." [GOC:dph] +synonym: "negative regulation of progesterone anabolism" EXACT [GOC:obol] +synonym: "negative regulation of progesterone biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of progesterone formation" EXACT [GOC:obol] +synonym: "negative regulation of progesterone synthesis" EXACT [GOC:obol] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:2000182 ! regulation of progesterone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006701 ! progesterone biosynthetic process +relationship: negatively_regulates GO:0006701 ! progesterone biosynthetic process +created_by: dph +creation_date: 2010-10-14T07:36:10Z + +[Term] +id: GO:2000184 +name: positive regulation of progesterone biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process." [GOC:dph] +synonym: "positive regulation of progesterone anabolism" EXACT [GOC:obol] +synonym: "positive regulation of progesterone biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of progesterone formation" EXACT [GOC:obol] +synonym: "positive regulation of progesterone synthesis" EXACT [GOC:obol] +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:2000182 ! regulation of progesterone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006701 ! progesterone biosynthetic process +relationship: positively_regulates GO:0006701 ! progesterone biosynthetic process +created_by: dph +creation_date: 2010-10-14T07:36:14Z + +[Term] +id: GO:2000185 +name: regulation of phosphate transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] +synonym: "regulation of phosphate membrane transport" EXACT [] +is_a: GO:0010966 ! regulation of phosphate transport +is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035435 ! phosphate ion transmembrane transport +relationship: regulates GO:0035435 ! phosphate ion transmembrane transport +created_by: vw +creation_date: 2010-10-15T11:33:04Z + +[Term] +id: GO:2000186 +name: negative regulation of phosphate transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] +synonym: "negative regulation of phosphate membrane transport" EXACT [] +is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport +is_a: GO:2000185 ! regulation of phosphate transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport +relationship: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport +created_by: vw +creation_date: 2010-10-15T11:33:08Z + +[Term] +id: GO:2000187 +name: positive regulation of phosphate transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] +synonym: "positive regulation of phosphate membrane transport" EXACT [] +is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport +is_a: GO:2000185 ! regulation of phosphate transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035435 ! phosphate ion transmembrane transport +relationship: positively_regulates GO:0035435 ! phosphate ion transmembrane transport +created_by: vw +creation_date: 2010-10-15T11:33:10Z + +[Term] +id: GO:2000190 +name: obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor." [GOC:BHF] +comment: This term was made obsolete because it makes no sense and was added in error. +synonym: "negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor" EXACT [] +is_obsolete: true +consider: GO:0000122 +consider: GO:0004879 +consider: GO:0030374 +consider: GO:0030522 +created_by: rl +creation_date: 2010-10-18T10:02:57Z + +[Term] +id: GO:2000191 +name: regulation of fatty acid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fatty acid transport." [GOC:BHF] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0032890 ! regulation of organic acid transport +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015908 ! fatty acid transport +relationship: regulates GO:0015908 ! fatty acid transport +created_by: rl +creation_date: 2010-10-18T10:37:13Z + +[Term] +id: GO:2000192 +name: negative regulation of fatty acid transport +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport." [GOC:BHF] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0032891 ! negative regulation of organic acid transport +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:2000191 ! regulation of fatty acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015908 ! fatty acid transport +relationship: negatively_regulates GO:0015908 ! fatty acid transport +created_by: rl +creation_date: 2010-10-18T10:37:15Z + +[Term] +id: GO:2000193 +name: positive regulation of fatty acid transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fatty acid transport." [GOC:BHF] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0032892 ! positive regulation of organic acid transport +is_a: GO:1903793 ! positive regulation of anion transport +is_a: GO:2000191 ! regulation of fatty acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015908 ! fatty acid transport +relationship: positively_regulates GO:0015908 ! fatty acid transport +created_by: rl +creation_date: 2010-10-18T10:37:17Z + +[Term] +id: GO:2000194 +name: regulation of female gonad development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol] +synonym: "regulation of ovarian development" EXACT [GOC:obol] +synonym: "regulation of ovary development" EXACT [GOC:obol] +is_a: GO:1905939 ! regulation of gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008585 ! female gonad development +relationship: regulates GO:0008585 ! female gonad development +created_by: yaf +creation_date: 2010-10-19T10:45:34Z + +[Term] +id: GO:2000195 +name: negative regulation of female gonad development +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol] +synonym: "negative regulation of ovarian development" EXACT [GOC:obol] +synonym: "negative regulation of ovary development" EXACT [GOC:obol] +is_a: GO:1905940 ! negative regulation of gonad development +is_a: GO:2000194 ! regulation of female gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008585 ! female gonad development +relationship: negatively_regulates GO:0008585 ! female gonad development +created_by: yaf +creation_date: 2010-10-19T10:45:38Z + +[Term] +id: GO:2000196 +name: positive regulation of female gonad development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol] +synonym: "positive regulation of ovarian development" EXACT [GOC:obol] +synonym: "positive regulation of ovary development" EXACT [GOC:obol] +is_a: GO:1905941 ! positive regulation of gonad development +is_a: GO:2000194 ! regulation of female gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008585 ! female gonad development +relationship: positively_regulates GO:0008585 ! female gonad development +created_by: yaf +creation_date: 2010-10-19T10:45:41Z + +[Term] +id: GO:2000197 +name: regulation of ribonucleoprotein complex localization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] +synonym: "regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] +synonym: "regulation of RNP localization" EXACT [GOC:obol] +is_a: GO:0060341 ! regulation of cellular localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071166 ! ribonucleoprotein complex localization +relationship: regulates GO:0071166 ! ribonucleoprotein complex localization +created_by: mah +creation_date: 2010-10-26T10:35:48Z + +[Term] +id: GO:2000198 +name: negative regulation of ribonucleoprotein complex localization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] +synonym: "negative regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "negative regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "negative regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] +synonym: "negative regulation of RNP localization" EXACT [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071166 ! ribonucleoprotein complex localization +relationship: negatively_regulates GO:0071166 ! ribonucleoprotein complex localization +created_by: mah +creation_date: 2010-10-26T10:35:52Z + +[Term] +id: GO:2000199 +name: positive regulation of ribonucleoprotein complex localization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization." [GOC:mah] +synonym: "positive regulation of cellular ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "positive regulation of establishment and maintenance of ribonucleoprotein complex localization" EXACT [GOC:obol] +synonym: "positive regulation of ribonucleoprotein complex localisation" EXACT [GOC:mah] +synonym: "positive regulation of RNP localization" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071166 ! ribonucleoprotein complex localization +relationship: positively_regulates GO:0071166 ! ribonucleoprotein complex localization +created_by: mah +creation_date: 2010-10-26T10:35:55Z + +[Term] +id: GO:2000200 +name: regulation of ribosomal subunit export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus." [GOC:mah] +synonym: "regulation of ribosomal subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal subunit export out of nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "regulation of ribosomal subunit-nucleus export" EXACT [GOC:obol] +synonym: "regulation of ribosome export from nucleus" RELATED [GOC:obol] +is_a: GO:0046825 ! regulation of protein export from nucleus +is_a: GO:0046831 ! regulation of RNA export from nucleus +is_a: GO:0090069 ! regulation of ribosome biogenesis +is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000054 ! ribosomal subunit export from nucleus +relationship: regulates GO:0000054 ! ribosomal subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:44:27Z + +[Term] +id: GO:2000201 +name: negative regulation of ribosomal subunit export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus." [GOC:mah] +synonym: "negative regulation of ribosomal subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal subunit export out of nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal subunit-nucleus export" EXACT [GOC:obol] +synonym: "negative regulation of ribosome export from nucleus" RELATED [GOC:obol] +is_a: GO:0046826 ! negative regulation of protein export from nucleus +is_a: GO:0046832 ! negative regulation of RNA export from nucleus +is_a: GO:0090071 ! negative regulation of ribosome biogenesis +is_a: GO:2000198 ! negative regulation of ribonucleoprotein complex localization +is_a: GO:2000200 ! regulation of ribosomal subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000054 ! ribosomal subunit export from nucleus +relationship: negatively_regulates GO:0000054 ! ribosomal subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:44:32Z + +[Term] +id: GO:2000202 +name: positive regulation of ribosomal subunit export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus." [GOC:mah] +synonym: "positive regulation of ribosomal subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal subunit export out of nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal subunit-nucleus export" EXACT [GOC:obol] +synonym: "positive regulation of ribosome export from nucleus" RELATED [GOC:obol] +is_a: GO:0046827 ! positive regulation of protein export from nucleus +is_a: GO:0046833 ! positive regulation of RNA export from nucleus +is_a: GO:0090070 ! positive regulation of ribosome biogenesis +is_a: GO:2000199 ! positive regulation of ribonucleoprotein complex localization +is_a: GO:2000200 ! regulation of ribosomal subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000054 ! ribosomal subunit export from nucleus +relationship: positively_regulates GO:0000054 ! ribosomal subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:44:36Z + +[Term] +id: GO:2000203 +name: regulation of ribosomal large subunit export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus." [GOC:mah] +synonym: "regulation of 50S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "regulation of 60S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "regulation of ribosomal large subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal large subunit export out of nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal large subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "regulation of ribosomal large subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000200 ! regulation of ribosomal subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000055 ! ribosomal large subunit export from nucleus +relationship: regulates GO:0000055 ! ribosomal large subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:52:36Z + +[Term] +id: GO:2000204 +name: negative regulation of ribosomal large subunit export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus." [GOC:mah] +synonym: "negative regulation of 50S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "negative regulation of 60S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "negative regulation of ribosomal large subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal large subunit export out of nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal large subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal large subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000201 ! negative regulation of ribosomal subunit export from nucleus +is_a: GO:2000203 ! regulation of ribosomal large subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000055 ! ribosomal large subunit export from nucleus +relationship: negatively_regulates GO:0000055 ! ribosomal large subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:52:39Z + +[Term] +id: GO:2000205 +name: positive regulation of ribosomal large subunit export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus." [GOC:mah] +synonym: "positive regulation of 50S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "positive regulation of 60S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "positive regulation of ribosomal large subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal large subunit export out of nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal large subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal large subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000202 ! positive regulation of ribosomal subunit export from nucleus +is_a: GO:2000203 ! regulation of ribosomal large subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000055 ! ribosomal large subunit export from nucleus +relationship: positively_regulates GO:0000055 ! ribosomal large subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:52:42Z + +[Term] +id: GO:2000206 +name: regulation of ribosomal small subunit export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus." [GOC:mah] +synonym: "regulation of 30S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "regulation of 40S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "regulation of ribosomal small subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal small subunit export out of nucleus" EXACT [GOC:obol] +synonym: "regulation of ribosomal small subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "regulation of ribosomal small subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000200 ! regulation of ribosomal subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000056 ! ribosomal small subunit export from nucleus +relationship: regulates GO:0000056 ! ribosomal small subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:54:09Z + +[Term] +id: GO:2000207 +name: negative regulation of ribosomal small subunit export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus." [GOC:mah] +synonym: "negative regulation of 30S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "negative regulation of 40S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "negative regulation of ribosomal small subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal small subunit export out of nucleus" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal small subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "negative regulation of ribosomal small subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000201 ! negative regulation of ribosomal subunit export from nucleus +is_a: GO:2000206 ! regulation of ribosomal small subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000056 ! ribosomal small subunit export from nucleus +relationship: negatively_regulates GO:0000056 ! ribosomal small subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:54:14Z + +[Term] +id: GO:2000208 +name: positive regulation of ribosomal small subunit export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus." [GOC:mah] +synonym: "positive regulation of 30S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "positive regulation of 40S ribosomal subunit export from nucleus" RELATED [GOC:obol] +synonym: "positive regulation of ribosomal small subunit export from cell nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal small subunit export out of nucleus" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal small subunit transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "positive regulation of ribosomal small subunit-nucleus export" EXACT [GOC:obol] +is_a: GO:2000202 ! positive regulation of ribosomal subunit export from nucleus +is_a: GO:2000206 ! regulation of ribosomal small subunit export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000056 ! ribosomal small subunit export from nucleus +relationship: positively_regulates GO:0000056 ! ribosomal small subunit export from nucleus +created_by: mah +creation_date: 2010-10-26T10:54:16Z + +[Term] +id: GO:2000209 +name: regulation of anoikis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anoikis." [GOC:mah] +synonym: "regulation of detachment induced cell death" EXACT [GOC:obol] +synonym: "regulation of suspension induced apoptosis" EXACT [GOC:obol] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043276 ! anoikis +relationship: regulates GO:0043276 ! anoikis +created_by: mah +creation_date: 2010-11-03T02:00:33Z + +[Term] +id: GO:2000210 +name: positive regulation of anoikis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anoikis." [GOC:mah] +synonym: "positive regulation of detachment induced cell death" EXACT [GOC:obol] +synonym: "positive regulation of suspension induced apoptosis" EXACT [GOC:obol] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:2000209 ! regulation of anoikis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043276 ! anoikis +relationship: positively_regulates GO:0043276 ! anoikis +created_by: mah +creation_date: 2010-11-03T02:00:36Z + +[Term] +id: GO:2000211 +name: regulation of glutamate metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamate metabolic process." [GOC:sl] +synonym: "regulation of glutamate metabolism" EXACT [GOC:obol] +synonym: "regulation of glutamic acid metabolic process" EXACT [GOC:obol] +synonym: "regulation of glutamic acid metabolism" EXACT [GOC:obol] +is_a: GO:0000820 ! regulation of glutamine family amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006536 ! glutamate metabolic process +relationship: regulates GO:0006536 ! glutamate metabolic process +created_by: mah +creation_date: 2010-11-03T02:43:51Z + +[Term] +id: GO:2000212 +name: negative regulation of glutamate metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process." [GOC:sl] +synonym: "negative regulation of glutamate metabolism" EXACT [GOC:obol] +synonym: "negative regulation of glutamic acid metabolic process" EXACT [GOC:obol] +synonym: "negative regulation of glutamic acid metabolism" EXACT [GOC:obol] +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:2000211 ! regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006536 ! glutamate metabolic process +relationship: negatively_regulates GO:0006536 ! glutamate metabolic process +created_by: mah +creation_date: 2010-11-03T02:43:55Z + +[Term] +id: GO:2000213 +name: positive regulation of glutamate metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamate metabolic process." [GOC:sl] +synonym: "positive regulation of glutamate metabolism" EXACT [GOC:obol] +synonym: "positive regulation of glutamic acid metabolic process" EXACT [GOC:obol] +synonym: "positive regulation of glutamic acid metabolism" EXACT [GOC:obol] +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:2000211 ! regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006536 ! glutamate metabolic process +relationship: positively_regulates GO:0006536 ! glutamate metabolic process +created_by: mah +creation_date: 2010-11-03T02:43:59Z + +[Term] +id: GO:2000214 +name: regulation of proline metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proline metabolic process." [GOC:sl] +synonym: "regulation of proline metabolism" EXACT [GOC:obol] +is_a: GO:0000820 ! regulation of glutamine family amino acid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006560 ! proline metabolic process +relationship: regulates GO:0006560 ! proline metabolic process +created_by: mah +creation_date: 2010-11-03T02:45:20Z + +[Term] +id: GO:2000215 +name: negative regulation of proline metabolic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process." [GOC:sl] +synonym: "negative regulation of proline metabolism" EXACT [GOC:obol] +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:2000214 ! regulation of proline metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006560 ! proline metabolic process +relationship: negatively_regulates GO:0006560 ! proline metabolic process +created_by: mah +creation_date: 2010-11-03T02:45:24Z + +[Term] +id: GO:2000216 +name: positive regulation of proline metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proline metabolic process." [GOC:sl] +synonym: "positive regulation of proline metabolism" EXACT [GOC:obol] +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:2000214 ! regulation of proline metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006560 ! proline metabolic process +relationship: positively_regulates GO:0006560 ! proline metabolic process +created_by: mah +creation_date: 2010-11-03T02:45:27Z + +[Term] +id: GO:2000217 +name: regulation of invasive growth in response to glucose limitation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation." [GOC:mah] +synonym: "regulation of colony morphology" RELATED [GOC:obol] +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001403 ! invasive growth in response to glucose limitation +relationship: regulates GO:0001403 ! invasive growth in response to glucose limitation +created_by: mah +creation_date: 2010-11-03T04:35:56Z + +[Term] +id: GO:2000218 +name: negative regulation of invasive growth in response to glucose limitation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation." [GOC:mah] +synonym: "negative regulation of colony morphology" RELATED [GOC:obol] +is_a: GO:0070785 ! negative regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:2000217 ! regulation of invasive growth in response to glucose limitation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001403 ! invasive growth in response to glucose limitation +relationship: negatively_regulates GO:0001403 ! invasive growth in response to glucose limitation +created_by: mah +creation_date: 2010-11-03T04:36:00Z + +[Term] +id: GO:2000219 +name: positive regulation of invasive growth in response to glucose limitation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation." [GOC:mah] +synonym: "positive regulation of colony morphology" RELATED [GOC:obol] +is_a: GO:0070786 ! positive regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:2000217 ! regulation of invasive growth in response to glucose limitation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001403 ! invasive growth in response to glucose limitation +relationship: positively_regulates GO:0001403 ! invasive growth in response to glucose limitation +created_by: mah +creation_date: 2010-11-03T04:36:02Z + +[Term] +id: GO:2000220 +name: regulation of pseudohyphal growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pseudohyphal growth." [GOC:mah] +is_a: GO:0001558 ! regulation of cell growth +is_a: GO:0070784 ! regulation of growth of unicellular organism as a thread of attached cells +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007124 ! pseudohyphal growth +relationship: regulates GO:0007124 ! pseudohyphal growth +created_by: mah +creation_date: 2010-11-03T04:36:56Z + +[Term] +id: GO:2000221 +name: negative regulation of pseudohyphal growth +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth." [GOC:mah] +is_a: GO:0030308 ! negative regulation of cell growth +is_a: GO:0070785 ! negative regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:2000220 ! regulation of pseudohyphal growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007124 ! pseudohyphal growth +relationship: negatively_regulates GO:0007124 ! pseudohyphal growth +created_by: mah +creation_date: 2010-11-03T04:37:00Z + +[Term] +id: GO:2000222 +name: positive regulation of pseudohyphal growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pseudohyphal growth." [GOC:mah] +is_a: GO:0030307 ! positive regulation of cell growth +is_a: GO:0070786 ! positive regulation of growth of unicellular organism as a thread of attached cells +is_a: GO:2000220 ! regulation of pseudohyphal growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007124 ! pseudohyphal growth +relationship: positively_regulates GO:0007124 ! pseudohyphal growth +created_by: mah +creation_date: 2010-11-03T04:37:03Z + +[Term] +id: GO:2000223 +name: regulation of BMP signaling pathway involved in heart jogging +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging." [GOC:BHF] +synonym: "regulation of BMP signalling pathway involved in heart jogging pathway involved in somitogenesis" EXACT [GOC:mah] +is_a: GO:0030510 ! regulation of BMP signaling pathway +is_a: GO:0045995 ! regulation of embryonic development +is_a: GO:1905330 ! regulation of morphogenesis of an epithelium +is_a: GO:2000826 ! regulation of heart morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003303 ! BMP signaling pathway involved in heart jogging +relationship: regulates GO:0003303 ! BMP signaling pathway involved in heart jogging +created_by: vk +creation_date: 2010-11-04T02:44:01Z + +[Term] +id: GO:2000224 +name: regulation of testosterone biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of testosterone biosynthetic process." [GOC:obol, GOC:yaf] +is_a: GO:0010566 ! regulation of ketone biosynthetic process +is_a: GO:0046885 ! regulation of hormone biosynthetic process +is_a: GO:0050810 ! regulation of steroid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061370 ! testosterone biosynthetic process +relationship: regulates GO:0061370 ! testosterone biosynthetic process +created_by: yaf +creation_date: 2010-11-09T10:38:33Z + +[Term] +id: GO:2000225 +name: negative regulation of testosterone biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process." [GOC:obol, GOC:yaf] +is_a: GO:0010894 ! negative regulation of steroid biosynthetic process +is_a: GO:0032353 ! negative regulation of hormone biosynthetic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:2000224 ! regulation of testosterone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061370 ! testosterone biosynthetic process +relationship: negatively_regulates GO:0061370 ! testosterone biosynthetic process +created_by: yaf +creation_date: 2010-11-09T10:38:37Z + +[Term] +id: GO:2000226 +name: regulation of pancreatic A cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] +synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003310 ! pancreatic A cell differentiation +relationship: regulates GO:0003310 ! pancreatic A cell differentiation +created_by: mah +creation_date: 2010-11-09T03:43:37Z + +[Term] +id: GO:2000227 +name: negative regulation of pancreatic A cell differentiation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] +synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000226 ! regulation of pancreatic A cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003310 ! pancreatic A cell differentiation +relationship: negatively_regulates GO:0003310 ! pancreatic A cell differentiation +created_by: mah +creation_date: 2010-11-09T03:43:40Z + +[Term] +id: GO:2000228 +name: positive regulation of pancreatic A cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] +synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000226 ! regulation of pancreatic A cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003310 ! pancreatic A cell differentiation +relationship: positively_regulates GO:0003310 ! pancreatic A cell differentiation +created_by: mah +creation_date: 2010-11-09T03:43:42Z + +[Term] +id: GO:2000229 +name: regulation of pancreatic stellate cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation." [GOC:mah] +is_a: GO:0048145 ! regulation of fibroblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072343 ! pancreatic stellate cell proliferation +relationship: regulates GO:0072343 ! pancreatic stellate cell proliferation +created_by: mah +creation_date: 2010-11-09T03:45:18Z + +[Term] +id: GO:2000230 +name: negative regulation of pancreatic stellate cell proliferation +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation." [GOC:mah] +is_a: GO:0048147 ! negative regulation of fibroblast proliferation +is_a: GO:2000229 ! regulation of pancreatic stellate cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072343 ! pancreatic stellate cell proliferation +relationship: negatively_regulates GO:0072343 ! pancreatic stellate cell proliferation +created_by: mah +creation_date: 2010-11-09T03:45:21Z + +[Term] +id: GO:2000231 +name: positive regulation of pancreatic stellate cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation." [GOC:mah] +is_a: GO:0048146 ! positive regulation of fibroblast proliferation +is_a: GO:2000229 ! regulation of pancreatic stellate cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072343 ! pancreatic stellate cell proliferation +relationship: positively_regulates GO:0072343 ! pancreatic stellate cell proliferation +created_by: mah +creation_date: 2010-11-09T03:45:23Z + +[Term] +id: GO:2000232 +name: regulation of rRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of rRNA processing." [GOC:mah] +synonym: "regulation of 35S primary transcript processing" RELATED [GOC:obol] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:0051252 ! regulation of RNA metabolic process +is_a: GO:0090069 ! regulation of ribosome biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006364 ! rRNA processing +relationship: regulates GO:0006364 ! rRNA processing +created_by: mah +creation_date: 2010-11-10T12:11:29Z + +[Term] +id: GO:2000233 +name: negative regulation of rRNA processing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing." [GOC:mah] +synonym: "negative regulation of 35S primary transcript processing" RELATED [GOC:obol] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:0090071 ! negative regulation of ribosome biogenesis +is_a: GO:2000232 ! regulation of rRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006364 ! rRNA processing +relationship: negatively_regulates GO:0006364 ! rRNA processing +created_by: mah +creation_date: 2010-11-10T12:11:33Z + +[Term] +id: GO:2000234 +name: positive regulation of rRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of rRNA processing." [GOC:mah] +synonym: "positive regulation of 35S primary transcript processing" RELATED [GOC:obol] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:0090070 ! positive regulation of ribosome biogenesis +is_a: GO:2000232 ! regulation of rRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006364 ! rRNA processing +relationship: positively_regulates GO:0006364 ! rRNA processing +created_by: mah +creation_date: 2010-11-10T12:11:36Z + +[Term] +id: GO:2000235 +name: regulation of tRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tRNA processing." [GOC:mah] +synonym: "regulation of tRNA maturation" EXACT [GOC:obol] +is_a: GO:0010468 ! regulation of gene expression +is_a: GO:1903326 ! regulation of tRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008033 ! tRNA processing +relationship: regulates GO:0008033 ! tRNA processing +created_by: mah +creation_date: 2010-11-10T12:15:08Z + +[Term] +id: GO:2000236 +name: negative regulation of tRNA processing +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing." [GOC:mah] +synonym: "negative regulation of tRNA maturation" EXACT [GOC:obol] +is_a: GO:0010629 ! negative regulation of gene expression +is_a: GO:1903327 ! negative regulation of tRNA metabolic process +is_a: GO:2000235 ! regulation of tRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008033 ! tRNA processing +relationship: negatively_regulates GO:0008033 ! tRNA processing +created_by: mah +creation_date: 2010-11-10T12:15:13Z + +[Term] +id: GO:2000237 +name: positive regulation of tRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA processing." [GOC:mah] +synonym: "positive regulation of tRNA maturation" EXACT [GOC:obol] +is_a: GO:0010628 ! positive regulation of gene expression +is_a: GO:1903328 ! positive regulation of tRNA metabolic process +is_a: GO:2000235 ! regulation of tRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008033 ! tRNA processing +relationship: positively_regulates GO:0008033 ! tRNA processing +created_by: mah +creation_date: 2010-11-10T12:15:17Z + +[Term] +id: GO:2000238 +name: regulation of tRNA export from nucleus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] +synonym: "regulation of tRNA export from cell nucleus" EXACT [GOC:obol] +synonym: "regulation of tRNA export out of nucleus" EXACT [GOC:obol] +synonym: "regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "regulation of tRNA-nucleus export" EXACT [GOC:obol] +is_a: GO:0046825 ! regulation of protein export from nucleus +is_a: GO:0046831 ! regulation of RNA export from nucleus +is_a: GO:2000197 ! regulation of ribonucleoprotein complex localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006409 ! tRNA export from nucleus +relationship: regulates GO:0006409 ! tRNA export from nucleus +created_by: mah +creation_date: 2010-11-10T12:39:33Z + +[Term] +id: GO:2000239 +name: negative regulation of tRNA export from nucleus +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] +synonym: "negative regulation of tRNA export from cell nucleus" EXACT [GOC:obol] +synonym: "negative regulation of tRNA export out of nucleus" EXACT [GOC:obol] +synonym: "negative regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "negative regulation of tRNA-nucleus export" EXACT [GOC:obol] +is_a: GO:0046826 ! negative regulation of protein export from nucleus +is_a: GO:0046832 ! negative regulation of RNA export from nucleus +is_a: GO:2000198 ! negative regulation of ribonucleoprotein complex localization +is_a: GO:2000238 ! regulation of tRNA export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006409 ! tRNA export from nucleus +relationship: negatively_regulates GO:0006409 ! tRNA export from nucleus +created_by: mah +creation_date: 2010-11-10T12:39:36Z + +[Term] +id: GO:2000240 +name: positive regulation of tRNA export from nucleus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus." [GOC:mah] +synonym: "positive regulation of tRNA export from cell nucleus" EXACT [GOC:obol] +synonym: "positive regulation of tRNA export out of nucleus" EXACT [GOC:obol] +synonym: "positive regulation of tRNA transport from nucleus to cytoplasm" EXACT [GOC:obol] +synonym: "positive regulation of tRNA-nucleus export" EXACT [GOC:obol] +is_a: GO:0046827 ! positive regulation of protein export from nucleus +is_a: GO:0046833 ! positive regulation of RNA export from nucleus +is_a: GO:2000199 ! positive regulation of ribonucleoprotein complex localization +is_a: GO:2000238 ! regulation of tRNA export from nucleus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006409 ! tRNA export from nucleus +relationship: positively_regulates GO:0006409 ! tRNA export from nucleus +created_by: mah +creation_date: 2010-11-10T12:39:38Z + +[Term] +id: GO:2000241 +name: regulation of reproductive process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah] +is_a: GO:0050789 ! regulation of biological process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0022414 ! reproductive process +relationship: regulates GO:0022414 ! reproductive process +created_by: mah +creation_date: 2010-11-10T02:44:02Z + +[Term] +id: GO:2000242 +name: negative regulation of reproductive process +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0022414 ! reproductive process +relationship: negatively_regulates GO:0022414 ! reproductive process +created_by: mah +creation_date: 2010-11-10T02:44:05Z + +[Term] +id: GO:2000243 +name: positive regulation of reproductive process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah] +is_a: GO:0048518 ! positive regulation of biological process +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0022414 ! reproductive process +relationship: positively_regulates GO:0022414 ! reproductive process +created_by: mah +creation_date: 2010-11-10T02:44:08Z + +[Term] +id: GO:2000244 +name: regulation of FtsZ-dependent cytokinesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis." [GOC:mah] +synonym: "regulation of prokaryote-type cytokinesis" RELATED [GOC:obol] +synonym: "regulation of prokaryotic fission" RELATED [GOC:obol] +is_a: GO:0032465 ! regulation of cytokinesis +is_a: GO:1903664 ! regulation of asexual reproduction +is_a: GO:2000241 ! regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043093 ! FtsZ-dependent cytokinesis +relationship: regulates GO:0043093 ! FtsZ-dependent cytokinesis +created_by: mah +creation_date: 2010-11-10T02:46:36Z + +[Term] +id: GO:2000245 +name: negative regulation of FtsZ-dependent cytokinesis +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis." [GOC:mah] +synonym: "negative regulation of prokaryote-type cytokinesis" RELATED [GOC:obol] +synonym: "negative regulation of prokaryotic fission" RELATED [GOC:obol] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:1903665 ! negative regulation of asexual reproduction +is_a: GO:2000242 ! negative regulation of reproductive process +is_a: GO:2000244 ! regulation of FtsZ-dependent cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043093 ! FtsZ-dependent cytokinesis +relationship: negatively_regulates GO:0043093 ! FtsZ-dependent cytokinesis +created_by: mah +creation_date: 2010-11-10T02:46:39Z + +[Term] +id: GO:2000246 +name: positive regulation of FtsZ-dependent cytokinesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis." [GOC:mah] +synonym: "positive regulation of prokaryote-type cytokinesis" RELATED [GOC:obol] +synonym: "positive regulation of prokaryotic fission" RELATED [GOC:obol] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:1903666 ! positive regulation of asexual reproduction +is_a: GO:2000243 ! positive regulation of reproductive process +is_a: GO:2000244 ! regulation of FtsZ-dependent cytokinesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043093 ! FtsZ-dependent cytokinesis +relationship: positively_regulates GO:0043093 ! FtsZ-dependent cytokinesis +created_by: mah +creation_date: 2010-11-10T02:46:41Z + +[Term] +id: GO:2000247 +name: positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape." [GOC:obol] +is_a: GO:2000100 ! regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +is_a: GO:2000771 ! positive regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +relationship: positively_regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: vw +creation_date: 2010-11-11T11:39:34Z + +[Term] +id: GO:2000248 +name: negative regulation of establishment or maintenance of neuroblast polarity +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol] +synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol] +is_a: GO:0007406 ! negative regulation of neuroblast proliferation +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity +is_a: GO:0045769 ! negative regulation of asymmetric cell division +is_a: GO:2000035 ! regulation of stem cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity +relationship: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity +created_by: vw +creation_date: 2010-11-11T11:40:34Z + +[Term] +id: GO:2000249 +name: regulation of actin cytoskeleton reorganization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization." [GOC:BHF] +synonym: "regulation of actin cytoskeleton remodeling" EXACT [GOC:obol] +synonym: "regulation of actin cytoskeleton reorganisation" EXACT [GOC:obol] +is_a: GO:0032956 ! regulation of actin cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031532 ! actin cytoskeleton reorganization +relationship: regulates GO:0031532 ! actin cytoskeleton reorganization +created_by: vk +creation_date: 2010-11-11T01:25:26Z + +[Term] +id: GO:2000250 +name: negative regulation of actin cytoskeleton reorganization +namespace: biological_process +def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization." [GOC:BHF] +synonym: "negative regulation of actin cytoskeleton remodeling" EXACT [GOC:obol] +synonym: "negative regulation of actin cytoskeleton reorganisation" EXACT [GOC:obol] +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:2000249 ! regulation of actin cytoskeleton reorganization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031532 ! actin cytoskeleton reorganization +relationship: negatively_regulates GO:0031532 ! actin cytoskeleton reorganization +created_by: vk +creation_date: 2010-11-11T01:25:29Z + +[Term] +id: GO:2000251 +name: positive regulation of actin cytoskeleton reorganization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization." [GOC:BHF] +synonym: "positive regulation of actin cytoskeleton remodeling" EXACT [GOC:obol] +synonym: "positive regulation of actin cytoskeleton reorganisation" EXACT [GOC:obol] +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:2000249 ! regulation of actin cytoskeleton reorganization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031532 ! actin cytoskeleton reorganization +relationship: positively_regulates GO:0031532 ! actin cytoskeleton reorganization +created_by: vk +creation_date: 2010-11-11T01:25:32Z + +[Term] +id: GO:2000252 +name: negative regulation of feeding behavior +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior." [GOC:obol] +synonym: "negative regulation of behavioral response to food" EXACT [GOC:obol] +synonym: "negative regulation of behavioural response to food" EXACT [GOC:obol] +synonym: "negative regulation of drinking" RELATED [GOC:obol] +synonym: "negative regulation of eating" RELATED [GOC:obol] +synonym: "negative regulation of feeding behaviour" EXACT [GOC:obol] +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:0060259 ! regulation of feeding behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007631 ! feeding behavior +relationship: negatively_regulates GO:0007631 ! feeding behavior +created_by: yaf +creation_date: 2010-11-18T11:24:14Z + +[Term] +id: GO:2000253 +name: positive regulation of feeding behavior +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of feeding behavior." [GOC:obol] +synonym: "positive regulation of behavioral response to food" EXACT [GOC:obol] +synonym: "positive regulation of behavioural response to food" EXACT [GOC:obol] +synonym: "positive regulation of drinking" RELATED [GOC:obol] +synonym: "positive regulation of eating" RELATED [GOC:obol] +synonym: "positive regulation of feeding behaviour" EXACT [GOC:obol] +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:0060259 ! regulation of feeding behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007631 ! feeding behavior +relationship: positively_regulates GO:0007631 ! feeding behavior +created_by: yaf +creation_date: 2010-11-18T11:24:18Z + +[Term] +id: GO:2000254 +name: regulation of male germ cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol] +is_a: GO:1905936 ! regulation of germ cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002176 ! male germ cell proliferation +relationship: regulates GO:0002176 ! male germ cell proliferation +created_by: dph +creation_date: 2010-11-18T09:29:44Z + +[Term] +id: GO:2000255 +name: negative regulation of male germ cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol] +is_a: GO:1905937 ! negative regulation of germ cell proliferation +is_a: GO:2000254 ! regulation of male germ cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002176 ! male germ cell proliferation +relationship: negatively_regulates GO:0002176 ! male germ cell proliferation +created_by: dph +creation_date: 2010-11-18T09:29:47Z + +[Term] +id: GO:2000256 +name: positive regulation of male germ cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol] +is_a: GO:1905938 ! positive regulation of germ cell proliferation +is_a: GO:2000254 ! regulation of male germ cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002176 ! male germ cell proliferation +relationship: positively_regulates GO:0002176 ! male germ cell proliferation +created_by: dph +creation_date: 2010-11-18T09:29:50Z + +[Term] +id: GO:2000257 +name: regulation of protein activation cascade +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein activation cascade." [GOC:mah] +synonym: "regulation of protein activation pathway" EXACT [GOC:obol] +synonym: "regulation of protein activitory cascade" EXACT [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0051246 ! regulation of protein metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072376 ! protein activation cascade +relationship: regulates GO:0072376 ! protein activation cascade +created_by: mah +creation_date: 2010-11-23T11:33:46Z + +[Term] +id: GO:2000258 +name: negative regulation of protein activation cascade +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade." [GOC:mah] +synonym: "negative regulation of protein activation pathway" EXACT [GOC:obol] +synonym: "negative regulation of protein activitory cascade" EXACT [GOC:obol] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0051248 ! negative regulation of protein metabolic process +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072376 ! protein activation cascade +relationship: negatively_regulates GO:0072376 ! protein activation cascade +created_by: mah +creation_date: 2010-11-23T11:33:51Z + +[Term] +id: GO:2000259 +name: positive regulation of protein activation cascade +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein activation cascade." [GOC:mah] +synonym: "positive regulation of protein activation pathway" EXACT [GOC:obol] +synonym: "positive regulation of protein activitory cascade" EXACT [GOC:obol] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0051247 ! positive regulation of protein metabolic process +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072376 ! protein activation cascade +relationship: positively_regulates GO:0072376 ! protein activation cascade +created_by: mah +creation_date: 2010-11-23T11:33:55Z + +[Term] +id: GO:2000260 +name: regulation of blood coagulation, common pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood coagulation, common pathway." [GOC:mah] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072377 ! blood coagulation, common pathway +relationship: regulates GO:0072377 ! blood coagulation, common pathway +created_by: mah +creation_date: 2010-11-23T11:42:40Z + +[Term] +id: GO:2000261 +name: negative regulation of blood coagulation, common pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway." [GOC:mah] +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:2000258 ! negative regulation of protein activation cascade +is_a: GO:2000260 ! regulation of blood coagulation, common pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072377 ! blood coagulation, common pathway +relationship: negatively_regulates GO:0072377 ! blood coagulation, common pathway +created_by: mah +creation_date: 2010-11-23T11:42:44Z + +[Term] +id: GO:2000262 +name: positive regulation of blood coagulation, common pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway." [GOC:mah] +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:2000259 ! positive regulation of protein activation cascade +is_a: GO:2000260 ! regulation of blood coagulation, common pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072377 ! blood coagulation, common pathway +relationship: positively_regulates GO:0072377 ! blood coagulation, common pathway +created_by: mah +creation_date: 2010-11-23T11:42:48Z + +[Term] +id: GO:2000263 +name: regulation of blood coagulation, extrinsic pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway." [GOC:mah] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007598 ! blood coagulation, extrinsic pathway +relationship: regulates GO:0007598 ! blood coagulation, extrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:44:35Z + +[Term] +id: GO:2000264 +name: negative regulation of blood coagulation, extrinsic pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway." [GOC:mah] +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:2000258 ! negative regulation of protein activation cascade +is_a: GO:2000263 ! regulation of blood coagulation, extrinsic pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007598 ! blood coagulation, extrinsic pathway +relationship: negatively_regulates GO:0007598 ! blood coagulation, extrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:44:42Z + +[Term] +id: GO:2000265 +name: positive regulation of blood coagulation, extrinsic pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway." [GOC:mah] +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:2000259 ! positive regulation of protein activation cascade +is_a: GO:2000263 ! regulation of blood coagulation, extrinsic pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007598 ! blood coagulation, extrinsic pathway +relationship: positively_regulates GO:0007598 ! blood coagulation, extrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:44:46Z + +[Term] +id: GO:2000266 +name: regulation of blood coagulation, intrinsic pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway." [GOC:mah] +is_a: GO:0030193 ! regulation of blood coagulation +is_a: GO:2000257 ! regulation of protein activation cascade +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007597 ! blood coagulation, intrinsic pathway +relationship: regulates GO:0007597 ! blood coagulation, intrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:45:40Z + +[Term] +id: GO:2000267 +name: negative regulation of blood coagulation, intrinsic pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway." [GOC:mah] +is_a: GO:0030195 ! negative regulation of blood coagulation +is_a: GO:2000258 ! negative regulation of protein activation cascade +is_a: GO:2000266 ! regulation of blood coagulation, intrinsic pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007597 ! blood coagulation, intrinsic pathway +relationship: negatively_regulates GO:0007597 ! blood coagulation, intrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:45:46Z + +[Term] +id: GO:2000268 +name: positive regulation of blood coagulation, intrinsic pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway." [GOC:mah] +is_a: GO:0030194 ! positive regulation of blood coagulation +is_a: GO:2000259 ! positive regulation of protein activation cascade +is_a: GO:2000266 ! regulation of blood coagulation, intrinsic pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007597 ! blood coagulation, intrinsic pathway +relationship: positively_regulates GO:0007597 ! blood coagulation, intrinsic pathway +created_by: mah +creation_date: 2010-11-23T11:45:51Z + +[Term] +id: GO:2000269 +name: regulation of fibroblast apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] +synonym: "regulation of fibroblast apoptosis" NARROW [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044346 ! fibroblast apoptotic process +relationship: regulates GO:0044346 ! fibroblast apoptotic process +created_by: jl +creation_date: 2010-11-23T01:07:23Z + +[Term] +id: GO:2000270 +name: negative regulation of fibroblast apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] +synonym: "negative regulation of fibroblast apoptosis" NARROW [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:2000269 ! regulation of fibroblast apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044346 ! fibroblast apoptotic process +relationship: negatively_regulates GO:0044346 ! fibroblast apoptotic process +created_by: jl +creation_date: 2010-11-23T01:07:27Z + +[Term] +id: GO:2000271 +name: positive regulation of fibroblast apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] +synonym: "positive regulation of fibroblast apoptosis" NARROW [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:2000269 ! regulation of fibroblast apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044346 ! fibroblast apoptotic process +relationship: positively_regulates GO:0044346 ! fibroblast apoptotic process +created_by: jl +creation_date: 2010-11-23T01:07:29Z + +[Term] +id: GO:2000272 +name: negative regulation of signaling receptor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity." [GOC:obol] +synonym: "negative regulation of receptor activity" BROAD [] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0044092 ! negative regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038023 ! signaling receptor activity +relationship: negatively_regulates GO:0038023 ! signaling receptor activity +created_by: bf +creation_date: 2010-12-02T09:28:47Z + +[Term] +id: GO:2000273 +name: positive regulation of signaling receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling receptor activity." [GOC:obol] +is_a: GO:0010469 ! regulation of signaling receptor activity +is_a: GO:0044093 ! positive regulation of molecular function +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038023 ! signaling receptor activity +relationship: positively_regulates GO:0038023 ! signaling receptor activity +created_by: bf +creation_date: 2010-12-02T09:28:50Z + +[Term] +id: GO:2000274 +name: regulation of epithelial cell migration, open tracheal system +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system." [GOC:obol] +synonym: "regulation of tracheal cell migration" RELATED [GOC:obol] +synonym: "regulation of tracheal epithelial cell migration" RELATED [GOC:obol] +is_a: GO:0010632 ! regulation of epithelial cell migration +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007427 ! epithelial cell migration, open tracheal system +relationship: regulates GO:0007427 ! epithelial cell migration, open tracheal system +created_by: sart +creation_date: 2010-12-03T02:08:43Z + +[Term] +id: GO:2000275 +name: regulation of oxidative phosphorylation uncoupler activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity." [GOC:mah] +synonym: "regulation of mitochondrial uncoupling protein activity" RELATED [GOC:obol] +synonym: "regulation of uncoupling protein activity" RELATED [GOC:obol] +is_a: GO:0010155 ! regulation of proton transport +is_a: GO:0022898 ! regulation of transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +relationship: regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +created_by: mah +creation_date: 2010-12-07T12:14:54Z + +[Term] +id: GO:2000276 +name: negative regulation of oxidative phosphorylation uncoupler activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity." [GOC:mah] +synonym: "negative regulation of mitochondrial uncoupling protein activity" RELATED [GOC:obol] +synonym: "negative regulation of uncoupling protein activity" RELATED [GOC:obol] +is_a: GO:0032410 ! negative regulation of transporter activity +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2000275 ! regulation of oxidative phosphorylation uncoupler activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +relationship: negatively_regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +created_by: mah +creation_date: 2010-12-07T12:14:59Z + +[Term] +id: GO:2000277 +name: positive regulation of oxidative phosphorylation uncoupler activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity." [GOC:mah] +synonym: "positive regulation of mitochondrial uncoupling protein activity" RELATED [GOC:obol] +synonym: "positive regulation of uncoupling protein activity" RELATED [GOC:obol] +is_a: GO:0032411 ! positive regulation of transporter activity +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2000275 ! regulation of oxidative phosphorylation uncoupler activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +relationship: positively_regulates GO:0017077 ! oxidative phosphorylation uncoupler activity +created_by: mah +creation_date: 2010-12-07T12:15:02Z + +[Term] +id: GO:2000278 +name: regulation of DNA biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] +synonym: "regulation of DNA anabolism" EXACT [GOC:obol] +synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol] +synonym: "regulation of DNA formation" EXACT [GOC:obol] +synonym: "regulation of DNA synthesis" EXACT [GOC:obol] +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071897 ! DNA biosynthetic process +relationship: regulates GO:0071897 ! DNA biosynthetic process +created_by: yaf +creation_date: 2010-12-08T04:48:15Z + +[Term] +id: GO:2000279 +name: negative regulation of DNA biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] +synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol] +synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of DNA formation" EXACT [GOC:obol] +synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol] +is_a: GO:0051053 ! negative regulation of DNA metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071897 ! DNA biosynthetic process +relationship: negatively_regulates GO:0071897 ! DNA biosynthetic process +created_by: yaf +creation_date: 2010-12-08T04:48:20Z + +[Term] +id: GO:2000280 +name: regulation of root development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of root development." [GOC:obol] +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048364 ! root development +relationship: regulates GO:0048364 ! root development +created_by: dhl +creation_date: 2010-12-08T09:30:21Z + +[Term] +id: GO:2000281 +name: regulation of histone H3-T3 phosphorylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation." [GOC:obol] +is_a: GO:0010799 ! regulation of peptidyl-threonine phosphorylation +is_a: GO:0033127 ! regulation of histone phosphorylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072355 ! histone H3-T3 phosphorylation +relationship: regulates GO:0072355 ! histone H3-T3 phosphorylation +created_by: vw +creation_date: 2010-12-10T11:48:31Z + +[Term] +id: GO:2000282 +name: regulation of cellular amino acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] +synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol] +synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] +synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] +synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] +is_a: GO:0006521 ! regulation of cellular amino acid metabolic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008652 ! cellular amino acid biosynthetic process +relationship: regulates GO:0008652 ! cellular amino acid biosynthetic process +created_by: vw +creation_date: 2010-12-10T11:54:19Z + +[Term] +id: GO:2000283 +name: negative regulation of cellular amino acid biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] +synonym: "negative regulation of amino acid biosynthetic process" EXACT [GOC:obol] +synonym: "negative regulation of cellular amino acid anabolism" EXACT [GOC:obol] +synonym: "negative regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellular amino acid formation" EXACT [GOC:obol] +synonym: "negative regulation of cellular amino acid synthesis" EXACT [GOC:obol] +is_a: GO:0031327 ! negative regulation of cellular biosynthetic process +is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008652 ! cellular amino acid biosynthetic process +relationship: negatively_regulates GO:0008652 ! cellular amino acid biosynthetic process +created_by: vw +creation_date: 2010-12-10T11:54:23Z + +[Term] +id: GO:2000284 +name: positive regulation of cellular amino acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] +synonym: "positive regulation of amino acid biosynthetic process" EXACT [GOC:obol] +synonym: "positive regulation of cellular amino acid anabolism" EXACT [GOC:obol] +synonym: "positive regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cellular amino acid formation" EXACT [GOC:obol] +synonym: "positive regulation of cellular amino acid synthesis" EXACT [GOC:obol] +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0045764 ! positive regulation of cellular amino acid metabolic process +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008652 ! cellular amino acid biosynthetic process +relationship: positively_regulates GO:0008652 ! cellular amino acid biosynthetic process +created_by: vw +creation_date: 2010-12-10T11:54:27Z + +[Term] +id: GO:2000285 +name: obsolete negative regulation of regulation of excitatory postsynaptic membrane potential +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential." [GOC:BHF] +comment: This term was made obsolete because it makes no sense and was added in error. +synonym: "negative regulation of EPSP" RELATED [GOC:obol] +synonym: "negative regulation of regulation of excitatory postsynaptic membrane potential" EXACT [] +is_obsolete: true +replaced_by: GO:0090394 +created_by: vk +creation_date: 2010-12-12T03:27:21Z + +[Term] +id: GO:2000286 +name: receptor internalization involved in canonical Wnt signaling pathway +namespace: biological_process +def: "A receptor internalization process that contributes to canonical Wnt signaling pathway." [GOC:BHF, GOC:mah, PMID:16890161] +synonym: "receptor internalization involved in canonical Wnt receptor signaling pathway" EXACT [] +synonym: "receptor internalization involved in canonical Wnt receptor signalling pathway" EXACT [GOC:obol] +synonym: "receptor internalization involved in canonical Wnt-activated signaling pathway" EXACT [GOC:signaling] +synonym: "receptor internalization involved in frizzled-1 receptor signaling pathway" RELATED [GOC:obol] +synonym: "receptor internalization involved in Wnt receptor signaling pathway through beta-catenin" EXACT [GOC:obol] +synonym: "receptor internalization involved in Wnt receptor signaling pathway via beta-catenin" EXACT [GOC:obol] +synonym: "receptor internalization involved in Wnt receptor signalling pathway through beta-catenin" EXACT [GOC:obol] +is_a: GO:0031623 ! receptor internalization +intersection_of: GO:0031623 ! receptor internalization +intersection_of: part_of GO:0060070 ! canonical Wnt signaling pathway +relationship: part_of GO:0060070 ! canonical Wnt signaling pathway +created_by: mah +creation_date: 2010-12-15T12:25:40Z + +[Term] +id: GO:2000287 +name: positive regulation of myotome development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF] +is_a: GO:0040019 ! positive regulation of embryonic development +is_a: GO:2000290 ! regulation of myotome development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061055 ! myotome development +relationship: positively_regulates GO:0061055 ! myotome development +created_by: rl +creation_date: 2010-12-16T05:17:15Z + +[Term] +id: GO:2000288 +name: positive regulation of myoblast proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:2000291 ! regulation of myoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051450 ! myoblast proliferation +relationship: positively_regulates GO:0051450 ! myoblast proliferation +created_by: rl +creation_date: 2010-12-16T05:20:52Z + +[Term] +id: GO:2000289 +name: regulation of photoreceptor cell axon guidance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance." [GOC:mah] +synonym: "regulation of photoreceptor cell axon pathfinding" EXACT [GOC:obol] +is_a: GO:1902667 ! regulation of axon guidance +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072499 ! photoreceptor cell axon guidance +relationship: regulates GO:0072499 ! photoreceptor cell axon guidance +created_by: mah +creation_date: 2010-12-17T10:04:35Z + +[Term] +id: GO:2000290 +name: regulation of myotome development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah] +is_a: GO:0045995 ! regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061055 ! myotome development +relationship: regulates GO:0061055 ! myotome development +created_by: mah +creation_date: 2010-12-20T10:22:05Z + +[Term] +id: GO:2000291 +name: regulation of myoblast proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah] +is_a: GO:0042127 ! regulation of cell population proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051450 ! myoblast proliferation +relationship: regulates GO:0051450 ! myoblast proliferation +created_by: mah +creation_date: 2010-12-20T10:34:26Z + +[Term] +id: GO:2000292 +name: regulation of defecation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol] +is_a: GO:0044062 ! regulation of excretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030421 ! defecation +relationship: regulates GO:0030421 ! defecation +created_by: bf +creation_date: 2010-12-21T09:23:08Z + +[Term] +id: GO:2000293 +name: negative regulation of defecation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol] +is_a: GO:0051048 ! negative regulation of secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000292 ! regulation of defecation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030421 ! defecation +relationship: negatively_regulates GO:0030421 ! defecation +created_by: bf +creation_date: 2010-12-21T09:23:13Z + +[Term] +id: GO:2000294 +name: positive regulation of defecation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol] +is_a: GO:0051047 ! positive regulation of secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000292 ! regulation of defecation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030421 ! defecation +relationship: positively_regulates GO:0030421 ! defecation +created_by: bf +creation_date: 2010-12-21T09:23:16Z + +[Term] +id: GO:2000295 +name: regulation of hydrogen peroxide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process." [GOC:BHF] +synonym: "regulation of detoxification of H2O2" RELATED [GOC:obol] +synonym: "regulation of detoxification of hydrogen peroxide" RELATED [GOC:obol] +synonym: "regulation of H2O2 catabolic process" EXACT [GOC:obol] +synonym: "regulation of H2O2 scavenging" RELATED [GOC:obol] +synonym: "regulation of hydrogen peroxide breakdown" EXACT [GOC:obol] +synonym: "regulation of hydrogen peroxide catabolism" EXACT [GOC:obol] +synonym: "regulation of hydrogen peroxide degradation" EXACT [GOC:obol] +synonym: "regulation of hydrogen peroxide removal" RELATED [GOC:obol] +synonym: "regulation of hydrogen peroxide scavenging" RELATED [GOC:obol] +is_a: GO:0010310 ! regulation of hydrogen peroxide metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042744 ! hydrogen peroxide catabolic process +relationship: regulates GO:0042744 ! hydrogen peroxide catabolic process +created_by: rl +creation_date: 2010-12-21T03:30:51Z + +[Term] +id: GO:2000296 +name: negative regulation of hydrogen peroxide catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process." [GOC:BHF] +synonym: "negative regulation of detoxification of H2O2" RELATED [GOC:obol] +synonym: "negative regulation of detoxification of hydrogen peroxide" RELATED [GOC:obol] +synonym: "negative regulation of H2O2 catabolic process" EXACT [GOC:obol] +synonym: "negative regulation of H2O2 scavenging" RELATED [GOC:obol] +synonym: "negative regulation of hydrogen peroxide breakdown" EXACT [GOC:obol] +synonym: "negative regulation of hydrogen peroxide catabolism" EXACT [GOC:obol] +synonym: "negative regulation of hydrogen peroxide degradation" EXACT [GOC:obol] +synonym: "negative regulation of hydrogen peroxide removal" RELATED [GOC:obol] +synonym: "negative regulation of hydrogen peroxide scavenging" RELATED [GOC:obol] +is_a: GO:0010727 ! negative regulation of hydrogen peroxide metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:2000295 ! regulation of hydrogen peroxide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042744 ! hydrogen peroxide catabolic process +relationship: negatively_regulates GO:0042744 ! hydrogen peroxide catabolic process +created_by: rl +creation_date: 2010-12-21T03:30:55Z + +[Term] +id: GO:2000297 +name: negative regulation of synapse maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation." [GOC:mah] +synonym: "negative regulation of synaptic maturation" EXACT [GOC:obol] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:0090128 ! regulation of synapse maturation +is_a: GO:1905809 ! negative regulation of synapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060074 ! synapse maturation +relationship: negatively_regulates GO:0060074 ! synapse maturation +created_by: mah +creation_date: 2010-12-23T11:37:31Z + +[Term] +id: GO:2000298 +name: regulation of Rho-dependent protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah] +synonym: "regulation of Rho-associated protein kinase activity" EXACT [GOC:obol] +synonym: "regulation of ROCK kinase activity" EXACT [GOC:obol] +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity +relationship: regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-12-23T11:44:50Z + +[Term] +id: GO:2000299 +name: negative regulation of Rho-dependent protein serine/threonine kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah] +synonym: "negative regulation of Rho-associated protein kinase activity" EXACT [GOC:obol] +synonym: "negative regulation of ROCK kinase activity" EXACT [GOC:obol] +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +is_a: GO:2000298 ! regulation of Rho-dependent protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity +relationship: negatively_regulates GO:0072518 ! Rho-dependent protein serine/threonine kinase activity +created_by: mah +creation_date: 2010-12-23T11:44:57Z + +[Term] +id: GO:2000300 +name: regulation of synaptic vesicle exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis." [GOC:obol] +subset: goslim_synapse +is_a: GO:0046928 ! regulation of neurotransmitter secretion +is_a: GO:0098693 ! regulation of synaptic vesicle cycle +is_a: GO:1903305 ! regulation of regulated secretory pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0016079 ! synaptic vesicle exocytosis +relationship: regulates GO:0016079 ! synaptic vesicle exocytosis +created_by: dph +creation_date: 2011-01-03T08:20:40Z + +[Term] +id: GO:2000301 +name: negative regulation of synaptic vesicle exocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis." [GOC:obol] +is_a: GO:0046929 ! negative regulation of neurotransmitter secretion +is_a: GO:1903306 ! negative regulation of regulated secretory pathway +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0016079 ! synaptic vesicle exocytosis +relationship: negatively_regulates GO:0016079 ! synaptic vesicle exocytosis +created_by: dph +creation_date: 2011-01-03T08:21:00Z + +[Term] +id: GO:2000302 +name: positive regulation of synaptic vesicle exocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis." [GOC:obol] +is_a: GO:0001956 ! positive regulation of neurotransmitter secretion +is_a: GO:1903307 ! positive regulation of regulated secretory pathway +is_a: GO:2000300 ! regulation of synaptic vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016079 ! synaptic vesicle exocytosis +relationship: positively_regulates GO:0016079 ! synaptic vesicle exocytosis +created_by: dph +creation_date: 2011-01-03T08:21:14Z + +[Term] +id: GO:2000303 +name: regulation of ceramide biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process." [GOC:dph] +synonym: "regulation of ceramide anabolism" EXACT [GOC:obol] +synonym: "regulation of ceramide biosynthesis" EXACT [GOC:obol] +synonym: "regulation of ceramide formation" EXACT [GOC:obol] +synonym: "regulation of ceramide synthesis" EXACT [GOC:obol] +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0090153 ! regulation of sphingolipid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046513 ! ceramide biosynthetic process +relationship: regulates GO:0046513 ! ceramide biosynthetic process +created_by: dph +creation_date: 2011-01-04T02:37:12Z + +[Term] +id: GO:2000304 +name: positive regulation of ceramide biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process." [GOC:dph] +synonym: "positive regulation of ceramide anabolism" EXACT [GOC:obol] +synonym: "positive regulation of ceramide biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of ceramide formation" EXACT [GOC:obol] +synonym: "positive regulation of ceramide synthesis" EXACT [GOC:obol] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0090154 ! positive regulation of sphingolipid biosynthetic process +is_a: GO:2000303 ! regulation of ceramide biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046513 ! ceramide biosynthetic process +relationship: positively_regulates GO:0046513 ! ceramide biosynthetic process +created_by: dph +creation_date: 2011-01-04T02:37:32Z + +[Term] +id: GO:2000305 +name: semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance +namespace: biological_process +def: "Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance." [GOC:obol] +synonym: "semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance" EXACT [GOC:obol] +synonym: "semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding" EXACT [GOC:obol] +synonym: "semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance" EXACT [GOC:obol] +synonym: "semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding" EXACT [GOC:obol] +is_a: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: GO:0071526 ! semaphorin-plexin signaling pathway +intersection_of: part_of GO:2000289 ! regulation of photoreceptor cell axon guidance +relationship: part_of GO:2000289 ! regulation of photoreceptor cell axon guidance +created_by: sart +creation_date: 2011-01-07T01:42:34Z + +[Term] +id: GO:2000306 +name: positive regulation of photomorphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of photomorphogenesis." [GOC:obol] +synonym: "positive regulation of plant development in response to light" EXACT [GOC:obol] +is_a: GO:0010099 ! regulation of photomorphogenesis +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:0048584 ! positive regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009640 ! photomorphogenesis +relationship: positively_regulates GO:0009640 ! photomorphogenesis +created_by: dhl +creation_date: 2011-01-12T07:09:02Z + +[Term] +id: GO:2000307 +name: regulation of tumor necrosis factor (ligand) superfamily member 11 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production." [GOC:BHF, GOC:mah] +synonym: "regulation of RANKL production" EXACT [GOC:obol] +synonym: "regulation of TNFSF11 production" EXACT [GOC:obol] +is_a: GO:1903555 ! regulation of tumor necrosis factor superfamily cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +relationship: regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +created_by: mah +creation_date: 2011-01-17T10:44:00Z + +[Term] +id: GO:2000308 +name: negative regulation of tumor necrosis factor (ligand) superfamily member 11 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production." [GOC:BHF, GOC:mah] +synonym: "negative regulation of RANKL production" EXACT [GOC:obol] +synonym: "negative regulation of TNFSF11 production" EXACT [GOC:obol] +is_a: GO:1903556 ! negative regulation of tumor necrosis factor superfamily cytokine production +is_a: GO:2000307 ! regulation of tumor necrosis factor (ligand) superfamily member 11 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +relationship: negatively_regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +created_by: mah +creation_date: 2011-01-17T10:44:33Z + +[Term] +id: GO:2000309 +name: positive regulation of tumor necrosis factor (ligand) superfamily member 11 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production." [GOC:BHF, GOC:mah] +synonym: "positive regulation of RANKL production" EXACT [GOC:obol] +synonym: "positive regulation of TNFSF11 production" EXACT [GOC:obol] +is_a: GO:1903557 ! positive regulation of tumor necrosis factor superfamily cytokine production +is_a: GO:2000307 ! regulation of tumor necrosis factor (ligand) superfamily member 11 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +relationship: positively_regulates GO:0072535 ! tumor necrosis factor (ligand) superfamily member 11 production +created_by: mah +creation_date: 2011-01-17T10:44:54Z + +[Term] +id: GO:2000310 +name: regulation of NMDA receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity." [GOC:BHF] +synonym: "regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [] +is_a: GO:0099601 ! regulation of neurotransmitter receptor activity +is_a: GO:1900449 ! regulation of glutamate receptor signaling pathway +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004972 ! NMDA glutamate receptor activity +relationship: regulates GO:0004972 ! NMDA glutamate receptor activity +created_by: bf +creation_date: 2011-01-18T10:06:37Z + +[Term] +id: GO:2000311 +name: regulation of AMPA receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity." [GOC:BHF] +synonym: "regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity" EXACT [] +is_a: GO:0099601 ! regulation of neurotransmitter receptor activity +is_a: GO:1900449 ! regulation of glutamate receptor signaling pathway +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004971 ! AMPA glutamate receptor activity +relationship: regulates GO:0004971 ! AMPA glutamate receptor activity +created_by: bf +creation_date: 2011-01-18T10:10:28Z + +[Term] +id: GO:2000312 +name: regulation of kainate selective glutamate receptor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity." [GOC:BHF] +is_a: GO:0099601 ! regulation of neurotransmitter receptor activity +is_a: GO:1900449 ! regulation of glutamate receptor signaling pathway +is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015277 ! kainate selective glutamate receptor activity +relationship: regulates GO:0015277 ! kainate selective glutamate receptor activity +created_by: bf +creation_date: 2011-01-18T10:14:16Z + +[Term] +id: GO:2000313 +name: regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF] +synonym: "regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol] +is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +relationship: regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +created_by: vk +creation_date: 2011-01-18T10:26:22Z + +[Term] +id: GO:2000314 +name: negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF] +synonym: "negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol] +is_a: GO:0040037 ! negative regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000313 ! regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +relationship: negatively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +created_by: vk +creation_date: 2011-01-18T10:26:56Z + +[Term] +id: GO:2000315 +name: positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation." [GOC:BHF] +synonym: "positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation" EXACT [GOC:obol] +is_a: GO:0045743 ! positive regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000313 ! regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +relationship: positively_regulates GO:0060825 ! fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +created_by: vk +creation_date: 2011-01-18T10:27:19Z + +[Term] +id: GO:2000316 +name: regulation of T-helper 17 type immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 17 type immune response." [GOC:BHF, GOC:mah] +synonym: "regulation of Th17 immune response" EXACT [GOC:obol] +is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072538 ! T-helper 17 type immune response +relationship: regulates GO:0072538 ! T-helper 17 type immune response +created_by: mah +creation_date: 2011-01-18T01:32:26Z + +[Term] +id: GO:2000317 +name: negative regulation of T-helper 17 type immune response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response." [GOC:BHF, GOC:mah] +synonym: "negative regulation of Th17 immune response" EXACT [GOC:obol] +is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:2000316 ! regulation of T-helper 17 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072538 ! T-helper 17 type immune response +relationship: negatively_regulates GO:0072538 ! T-helper 17 type immune response +created_by: mah +creation_date: 2011-01-18T01:33:00Z + +[Term] +id: GO:2000318 +name: positive regulation of T-helper 17 type immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response." [GOC:BHF, GOC:mah] +synonym: "positive regulation of Th17 immune response" EXACT [GOC:obol] +is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains +is_a: GO:2000316 ! regulation of T-helper 17 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072538 ! T-helper 17 type immune response +relationship: positively_regulates GO:0072538 ! T-helper 17 type immune response +created_by: mah +creation_date: 2011-01-18T01:33:24Z + +[Term] +id: GO:2000319 +name: regulation of T-helper 17 cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation." [GOC:BHF, GOC:mah] +synonym: "regulation of T-helper 17 cell development" RELATED [GOC:obol] +is_a: GO:0045622 ! regulation of T-helper cell differentiation +is_a: GO:2000316 ! regulation of T-helper 17 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072539 ! T-helper 17 cell differentiation +relationship: regulates GO:0072539 ! T-helper 17 cell differentiation +created_by: mah +creation_date: 2011-01-18T01:43:48Z + +[Term] +id: GO:2000320 +name: negative regulation of T-helper 17 cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation." [GOC:BHF, GOC:mah] +synonym: "negative regulation of T-helper 17 cell development" RELATED [GOC:obol] +is_a: GO:0045623 ! negative regulation of T-helper cell differentiation +is_a: GO:2000317 ! negative regulation of T-helper 17 type immune response +is_a: GO:2000319 ! regulation of T-helper 17 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072539 ! T-helper 17 cell differentiation +relationship: negatively_regulates GO:0072539 ! T-helper 17 cell differentiation +created_by: mah +creation_date: 2011-01-18T01:44:31Z + +[Term] +id: GO:2000321 +name: positive regulation of T-helper 17 cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation." [GOC:BHF, GOC:mah] +synonym: "positive regulation of T-helper 17 cell development" RELATED [GOC:obol] +is_a: GO:0045624 ! positive regulation of T-helper cell differentiation +is_a: GO:2000318 ! positive regulation of T-helper 17 type immune response +is_a: GO:2000319 ! regulation of T-helper 17 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072539 ! T-helper 17 cell differentiation +relationship: positively_regulates GO:0072539 ! T-helper 17 cell differentiation +created_by: mah +creation_date: 2011-01-18T01:45:08Z + +[Term] +id: GO:2000322 +name: regulation of glucocorticoid receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF] +synonym: "regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol] +is_a: GO:0033143 ! regulation of intracellular steroid hormone receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042921 ! glucocorticoid receptor signaling pathway +relationship: regulates GO:0042921 ! glucocorticoid receptor signaling pathway +created_by: vk +creation_date: 2011-01-18T04:38:10Z + +[Term] +id: GO:2000323 +name: negative regulation of glucocorticoid receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF] +synonym: "negative regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol] +is_a: GO:0033144 ! negative regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:2000322 ! regulation of glucocorticoid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042921 ! glucocorticoid receptor signaling pathway +relationship: negatively_regulates GO:0042921 ! glucocorticoid receptor signaling pathway +created_by: vk +creation_date: 2011-01-18T04:38:43Z + +[Term] +id: GO:2000324 +name: positive regulation of glucocorticoid receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF] +synonym: "positive regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol] +is_a: GO:0033145 ! positive regulation of intracellular steroid hormone receptor signaling pathway +is_a: GO:2000322 ! regulation of glucocorticoid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042921 ! glucocorticoid receptor signaling pathway +relationship: positively_regulates GO:0042921 ! glucocorticoid receptor signaling pathway +created_by: vk +creation_date: 2011-01-18T04:39:05Z + +[Term] +id: GO:2000325 +name: regulation of nuclear receptor transcription coactivator activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity." [GOC:BHF] +synonym: "regulation of ligand-dependent nuclear receptor transcription co-activator activity" EXACT [GOC:obol] +synonym: "regulation of ligand-dependent nuclear receptor transcription coactivator activity" EXACT [] +is_a: GO:0065009 ! regulation of molecular function +is_a: GO:1903506 ! regulation of nucleic acid-templated transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030374 ! nuclear receptor transcription coactivator activity +relationship: regulates GO:0030374 ! nuclear receptor transcription coactivator activity +created_by: vk +creation_date: 2011-01-18T06:29:32Z + +[Term] +id: GO:2000326 +name: negative regulation of nuclear receptor transcription coactivator activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity." [GOC:BHF] +synonym: "negative regulation of ligand-dependent nuclear receptor transcription co-activator activity" EXACT [GOC:obol] +synonym: "negative regulation of ligand-dependent nuclear receptor transcription coactivator activity" EXACT [] +is_a: GO:0044092 ! negative regulation of molecular function +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:2000325 ! regulation of nuclear receptor transcription coactivator activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030374 ! nuclear receptor transcription coactivator activity +relationship: negatively_regulates GO:0030374 ! nuclear receptor transcription coactivator activity +created_by: vk +creation_date: 2011-01-18T06:30:03Z + +[Term] +id: GO:2000327 +name: positive regulation of nuclear receptor transcription coactivator activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity." [GOC:BHF] +synonym: "positive regulation of ligand-dependent nuclear receptor transcription co-activator activity" EXACT [GOC:obol] +synonym: "positive regulation of ligand-dependent nuclear receptor transcription coactivator activity" EXACT [] +is_a: GO:0044093 ! positive regulation of molecular function +is_a: GO:1903508 ! positive regulation of nucleic acid-templated transcription +is_a: GO:2000325 ! regulation of nuclear receptor transcription coactivator activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030374 ! nuclear receptor transcription coactivator activity +relationship: positively_regulates GO:0030374 ! nuclear receptor transcription coactivator activity +created_by: vk +creation_date: 2011-01-18T06:30:23Z + +[Term] +id: GO:2000328 +name: regulation of T-helper 17 cell lineage commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment." [GOC:BHF, GOC:mah] +synonym: "regulation of T-helper 17 cell fate commitment" EXACT [GOC:obol] +synonym: "regulation of Th17 cell lineage commitment" EXACT [GOC:obol] +synonym: "regulation of Th17 fate commitment" EXACT [GOC:obol] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:2000319 ! regulation of T-helper 17 cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072540 ! T-helper 17 cell lineage commitment +relationship: regulates GO:0072540 ! T-helper 17 cell lineage commitment +created_by: mah +creation_date: 2011-01-19T09:31:19Z + +[Term] +id: GO:2000329 +name: negative regulation of T-helper 17 cell lineage commitment +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment." [GOC:BHF, GOC:mah] +synonym: "negative regulation of T-helper 17 cell fate commitment" EXACT [GOC:obol] +synonym: "negative regulation of Th17 cell lineage commitment" EXACT [GOC:obol] +synonym: "negative regulation of Th17 fate commitment" EXACT [GOC:obol] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:2000320 ! negative regulation of T-helper 17 cell differentiation +is_a: GO:2000328 ! regulation of T-helper 17 cell lineage commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072540 ! T-helper 17 cell lineage commitment +relationship: negatively_regulates GO:0072540 ! T-helper 17 cell lineage commitment +created_by: mah +creation_date: 2011-01-19T09:31:53Z + +[Term] +id: GO:2000330 +name: positive regulation of T-helper 17 cell lineage commitment +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment." [GOC:BHF, GOC:mah] +synonym: "positive regulation of T-helper 17 cell fate commitment" EXACT [GOC:obol] +synonym: "positive regulation of Th17 cell lineage commitment" EXACT [GOC:obol] +synonym: "positive regulation of Th17 fate commitment" EXACT [GOC:obol] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:2000321 ! positive regulation of T-helper 17 cell differentiation +is_a: GO:2000328 ! regulation of T-helper 17 cell lineage commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072540 ! T-helper 17 cell lineage commitment +relationship: positively_regulates GO:0072540 ! T-helper 17 cell lineage commitment +created_by: mah +creation_date: 2011-01-19T09:32:16Z + +[Term] +id: GO:2000331 +name: regulation of terminal button organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of terminal button organization." [GOC:BHF, GOC:mah] +synonym: "regulation of bouton organization" EXACT [GOC:obol] +synonym: "regulation of presynaptic bouton organization" EXACT [GOC:obol] +synonym: "regulation of synaptic bouton organization" EXACT [GOC:obol] +synonym: "regulation of terminal bouton organization" EXACT [GOC:obol] +synonym: "regulation of terminal button organisation" EXACT [GOC:obol] +is_a: GO:0099174 ! regulation of presynapse organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072553 ! terminal button organization +relationship: regulates GO:0072553 ! terminal button organization +created_by: mah +creation_date: 2011-01-28T11:29:08Z + +[Term] +id: GO:2000332 +name: regulation of blood microparticle formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of blood microparticle formation." [GOC:BHF, GOC:mah] +synonym: "regulation of microparticle generation" EXACT [GOC:obol] +synonym: "regulation of microparticle release" EXACT [GOC:obol] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051128 ! regulation of cellular component organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072564 ! blood microparticle formation +relationship: regulates GO:0072564 ! blood microparticle formation +created_by: mah +creation_date: 2011-01-31T11:18:11Z + +[Term] +id: GO:2000333 +name: negative regulation of blood microparticle formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation." [GOC:BHF, GOC:mah] +synonym: "negative regulation of microparticle generation" EXACT [GOC:obol] +synonym: "negative regulation of microparticle release" EXACT [GOC:obol] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:2000332 ! regulation of blood microparticle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072564 ! blood microparticle formation +relationship: negatively_regulates GO:0072564 ! blood microparticle formation +created_by: mah +creation_date: 2011-01-31T11:18:18Z + +[Term] +id: GO:2000334 +name: positive regulation of blood microparticle formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood microparticle formation." [GOC:BHF, GOC:mah] +synonym: "positive regulation of microparticle generation" EXACT [GOC:obol] +synonym: "positive regulation of microparticle release" EXACT [GOC:obol] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:2000332 ! regulation of blood microparticle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072564 ! blood microparticle formation +relationship: positively_regulates GO:0072564 ! blood microparticle formation +created_by: mah +creation_date: 2011-01-31T11:18:23Z + +[Term] +id: GO:2000335 +name: regulation of endothelial microparticle formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial microparticle formation." [GOC:BHF, GOC:mah] +synonym: "regulation of endothelial microparticle generation" EXACT [GOC:obol] +synonym: "regulation of endothelial microparticle release" EXACT [GOC:obol] +is_a: GO:2000332 ! regulation of blood microparticle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072565 ! endothelial microparticle formation +relationship: regulates GO:0072565 ! endothelial microparticle formation +created_by: mah +creation_date: 2011-01-31T11:20:26Z + +[Term] +id: GO:2000336 +name: negative regulation of endothelial microparticle formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation." [GOC:BHF, GOC:mah] +synonym: "negative regulation of endothelial microparticle generation" EXACT [GOC:obol] +synonym: "negative regulation of endothelial microparticle release" EXACT [GOC:obol] +is_a: GO:2000333 ! negative regulation of blood microparticle formation +is_a: GO:2000335 ! regulation of endothelial microparticle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072565 ! endothelial microparticle formation +relationship: negatively_regulates GO:0072565 ! endothelial microparticle formation +created_by: mah +creation_date: 2011-01-31T11:20:33Z + +[Term] +id: GO:2000337 +name: positive regulation of endothelial microparticle formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation." [GOC:BHF, GOC:mah] +synonym: "positive regulation of endothelial microparticle generation" EXACT [GOC:obol] +synonym: "positive regulation of endothelial microparticle release" EXACT [GOC:obol] +is_a: GO:2000334 ! positive regulation of blood microparticle formation +is_a: GO:2000335 ! regulation of endothelial microparticle formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072565 ! endothelial microparticle formation +relationship: positively_regulates GO:0072565 ! endothelial microparticle formation +created_by: mah +creation_date: 2011-01-31T11:20:38Z + +[Term] +id: GO:2000338 +name: regulation of chemokine (C-X-C motif) ligand 1 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production." [GOC:BHF, GOC:mah] +synonym: "regulation of CXCL1 production" EXACT [GOC:obol] +synonym: "regulation of KC production" EXACT [GOC:obol] +synonym: "regulation of keratinocyte derived chemokine production" EXACT [GOC:obol] +synonym: "regulation of SCYB1 production" EXACT [GOC:obol] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +relationship: regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +created_by: mah +creation_date: 2011-02-01T10:46:27Z + +[Term] +id: GO:2000339 +name: negative regulation of chemokine (C-X-C motif) ligand 1 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production." [GOC:BHF, GOC:mah] +synonym: "negative regulation of CXCL1 production" EXACT [GOC:obol] +synonym: "negative regulation of KC production" EXACT [GOC:obol] +synonym: "negative regulation of keratinocyte derived chemokine production" EXACT [GOC:obol] +synonym: "negative regulation of SCYB1 production" EXACT [GOC:obol] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:2000338 ! regulation of chemokine (C-X-C motif) ligand 1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +relationship: negatively_regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +created_by: mah +creation_date: 2011-02-01T10:46:31Z + +[Term] +id: GO:2000340 +name: positive regulation of chemokine (C-X-C motif) ligand 1 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production." [GOC:BHF, GOC:mah] +synonym: "positive regulation of CXCL1 production" EXACT [GOC:obol] +synonym: "positive regulation of KC production" EXACT [GOC:obol] +synonym: "positive regulation of keratinocyte derived chemokine production" EXACT [GOC:obol] +synonym: "positive regulation of SCYB1 production" EXACT [GOC:obol] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:2000338 ! regulation of chemokine (C-X-C motif) ligand 1 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +relationship: positively_regulates GO:0072566 ! chemokine (C-X-C motif) ligand 1 production +created_by: mah +creation_date: 2011-02-01T10:46:33Z + +[Term] +id: GO:2000341 +name: regulation of chemokine (C-X-C motif) ligand 2 production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production." [GOC:BHF, GOC:mah] +synonym: "regulation of CXCL2 production" EXACT [GOC:obol] +synonym: "regulation of MIP-2 production" EXACT [GOC:obol] +synonym: "regulation of MIP2 production" EXACT [GOC:obol] +synonym: "regulation of SCYB2 production" EXACT [GOC:obol] +is_a: GO:0032642 ! regulation of chemokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +relationship: regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +created_by: mah +creation_date: 2011-02-01T11:57:14Z + +[Term] +id: GO:2000342 +name: negative regulation of chemokine (C-X-C motif) ligand 2 production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production." [GOC:BHF, GOC:mah] +synonym: "negative regulation of CXCL2 production" EXACT [GOC:obol] +synonym: "negative regulation of MIP-2 production" EXACT [GOC:obol] +synonym: "negative regulation of MIP2 production" EXACT [GOC:obol] +synonym: "negative regulation of SCYB2 production" EXACT [GOC:obol] +is_a: GO:0032682 ! negative regulation of chemokine production +is_a: GO:2000341 ! regulation of chemokine (C-X-C motif) ligand 2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +relationship: negatively_regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +created_by: mah +creation_date: 2011-02-01T11:57:17Z + +[Term] +id: GO:2000343 +name: positive regulation of chemokine (C-X-C motif) ligand 2 production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production." [GOC:BHF, GOC:mah] +synonym: "positive regulation of CXCL2 production" EXACT [GOC:obol] +synonym: "positive regulation of MIP-2 production" EXACT [GOC:obol] +synonym: "positive regulation of MIP2 production" EXACT [GOC:obol] +synonym: "positive regulation of SCYB2 production" EXACT [GOC:obol] +is_a: GO:0032722 ! positive regulation of chemokine production +is_a: GO:2000341 ! regulation of chemokine (C-X-C motif) ligand 2 production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +relationship: positively_regulates GO:0072567 ! chemokine (C-X-C motif) ligand 2 production +created_by: mah +creation_date: 2011-02-01T11:57:20Z + +[Term] +id: GO:2000344 +name: positive regulation of acrosome reaction +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the acrosome reaction." [GOC:obol] +is_a: GO:0060046 ! regulation of acrosome reaction +is_a: GO:1905516 ! positive regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007340 ! acrosome reaction +relationship: positively_regulates GO:0007340 ! acrosome reaction +created_by: yaf +creation_date: 2011-02-01T12:02:18Z + +[Term] +id: GO:2000345 +name: regulation of hepatocyte proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatocyte proliferation." [GOC:BHF, GOC:mah] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072574 ! hepatocyte proliferation +relationship: regulates GO:0072574 ! hepatocyte proliferation +created_by: mah +creation_date: 2011-02-03T10:27:15Z + +[Term] +id: GO:2000346 +name: negative regulation of hepatocyte proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation." [GOC:BHF, GOC:mah] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000345 ! regulation of hepatocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072574 ! hepatocyte proliferation +relationship: negatively_regulates GO:0072574 ! hepatocyte proliferation +created_by: mah +creation_date: 2011-02-03T10:27:20Z + +[Term] +id: GO:2000347 +name: positive regulation of hepatocyte proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation." [GOC:BHF, GOC:mah] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000345 ! regulation of hepatocyte proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072574 ! hepatocyte proliferation +relationship: positively_regulates GO:0072574 ! hepatocyte proliferation +created_by: mah +creation_date: 2011-02-03T10:27:24Z + +[Term] +id: GO:2000348 +name: regulation of CD40 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway." [GOC:mah] +synonym: "regulation of CD40 signalling pathway" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0023035 ! CD40 signaling pathway +relationship: regulates GO:0023035 ! CD40 signaling pathway +created_by: mah +creation_date: 2011-02-03T10:29:40Z + +[Term] +id: GO:2000349 +name: negative regulation of CD40 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway." [GOC:BHF, GOC:mah] +synonym: "negative regulation of CD40 signalling pathway" EXACT [GOC:obol] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:2000348 ! regulation of CD40 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0023035 ! CD40 signaling pathway +relationship: negatively_regulates GO:0023035 ! CD40 signaling pathway +created_by: mah +creation_date: 2011-02-03T10:29:44Z + +[Term] +id: GO:2000350 +name: positive regulation of CD40 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway." [GOC:BHF, GOC:mah] +synonym: "positive regulation of CD40 signalling pathway" EXACT [GOC:obol] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:2000348 ! regulation of CD40 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0023035 ! CD40 signaling pathway +relationship: positively_regulates GO:0023035 ! CD40 signaling pathway +created_by: mah +creation_date: 2011-02-03T10:29:46Z + +[Term] +id: GO:2000351 +name: regulation of endothelial cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] +synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol] +synonym: "regulation of endothelial cell apoptosis" NARROW [] +synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] +synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol] +synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] +synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072577 ! endothelial cell apoptotic process +relationship: regulates GO:0072577 ! endothelial cell apoptotic process +created_by: mah +creation_date: 2011-02-03T10:43:16Z + +[Term] +id: GO:2000352 +name: negative regulation of endothelial cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol] +synonym: "negative regulation of endothelial cell apoptosis" NARROW [] +synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] +synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol] +synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] +synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:2000351 ! regulation of endothelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072577 ! endothelial cell apoptotic process +relationship: negatively_regulates GO:0072577 ! endothelial cell apoptotic process +created_by: mah +creation_date: 2011-02-03T10:43:20Z + +[Term] +id: GO:2000353 +name: positive regulation of endothelial cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] +synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol] +synonym: "positive regulation of endothelial cell apoptosis" NARROW [] +synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] +synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol] +synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] +synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:2000351 ! regulation of endothelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072577 ! endothelial cell apoptotic process +relationship: positively_regulates GO:0072577 ! endothelial cell apoptotic process +created_by: mah +creation_date: 2011-02-03T10:43:23Z + +[Term] +id: GO:2000354 +name: regulation of ovarian follicle development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ovarian follicle development." [GOC:obol] +synonym: "regulation of follicular phase" RELATED [GOC:obol] +is_a: GO:2000194 ! regulation of female gonad development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001541 ! ovarian follicle development +relationship: regulates GO:0001541 ! ovarian follicle development +created_by: yaf +creation_date: 2011-02-03T02:01:28Z + +[Term] +id: GO:2000355 +name: negative regulation of ovarian follicle development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development." [GOC:obol] +synonym: "negative regulation of follicular phase" RELATED [GOC:obol] +is_a: GO:2000195 ! negative regulation of female gonad development +is_a: GO:2000354 ! regulation of ovarian follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001541 ! ovarian follicle development +relationship: negatively_regulates GO:0001541 ! ovarian follicle development +created_by: yaf +creation_date: 2011-02-03T02:01:32Z + +[Term] +id: GO:2000356 +name: regulation of kidney smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation." [GOC:obol] +is_a: GO:0051150 ! regulation of smooth muscle cell differentiation +is_a: GO:0090183 ! regulation of kidney development +is_a: GO:1905899 ! regulation of smooth muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072195 ! kidney smooth muscle cell differentiation +relationship: regulates GO:0072195 ! kidney smooth muscle cell differentiation +created_by: yaf +creation_date: 2011-02-03T02:14:24Z + +[Term] +id: GO:2000357 +name: negative regulation of kidney smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation." [GOC:obol] +is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:1905900 ! negative regulation of smooth muscle tissue development +is_a: GO:2000356 ! regulation of kidney smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072195 ! kidney smooth muscle cell differentiation +relationship: negatively_regulates GO:0072195 ! kidney smooth muscle cell differentiation +created_by: yaf +creation_date: 2011-02-03T02:14:28Z + +[Term] +id: GO:2000358 +name: positive regulation of kidney smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation." [GOC:obol] +is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:1905901 ! positive regulation of smooth muscle tissue development +is_a: GO:2000356 ! regulation of kidney smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072195 ! kidney smooth muscle cell differentiation +relationship: positively_regulates GO:0072195 ! kidney smooth muscle cell differentiation +created_by: yaf +creation_date: 2011-02-03T02:14:31Z + +[Term] +id: GO:2000359 +name: regulation of binding of sperm to zona pellucida +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida." [GOC:obol] +synonym: "regulation of ZPG binding" RELATED [GOC:obol] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0080154 ! regulation of fertilization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007339 ! binding of sperm to zona pellucida +relationship: regulates GO:0007339 ! binding of sperm to zona pellucida +created_by: yaf +creation_date: 2011-02-03T02:42:50Z + +[Term] +id: GO:2000360 +name: negative regulation of binding of sperm to zona pellucida +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida." [GOC:obol] +synonym: "negative regulation of ZPG binding" RELATED [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0060467 ! negative regulation of fertilization +is_a: GO:2000359 ! regulation of binding of sperm to zona pellucida +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007339 ! binding of sperm to zona pellucida +relationship: negatively_regulates GO:0007339 ! binding of sperm to zona pellucida +created_by: yaf +creation_date: 2011-02-03T02:42:54Z + +[Term] +id: GO:2000361 +name: regulation of prostaglandin-E synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity." [GOC:BHF] +synonym: "regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [GOC:obol] +synonym: "regulation of endoperoxide isomerase activity" EXACT [GOC:obol] +synonym: "regulation of PGE isomerase activity" EXACT [GOC:obol] +synonym: "regulation of PGE2 isomerase activity" EXACT [GOC:obol] +synonym: "regulation of PGH-PGE isomerase activity" EXACT [GOC:obol] +synonym: "regulation of prostaglandin endoperoxide E isomerase activity" EXACT [GOC:obol] +synonym: "regulation of prostaglandin endoperoxide E2 isomerase activity" EXACT [GOC:obol] +synonym: "regulation of prostaglandin H-E isomerase activity" EXACT [GOC:obol] +synonym: "regulation of prostaglandin R-prostaglandin E isomerase activity" EXACT [GOC:obol] +synonym: "regulation of Prostaglandin-H(2) E-isomerase activity" EXACT [GOC:obol] +synonym: "regulation of prostaglandin-H2 E-isomerase activity" EXACT [GOC:obol] +is_a: GO:0010911 ! regulation of isomerase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0050220 ! prostaglandin-E synthase activity +relationship: regulates GO:0050220 ! prostaglandin-E synthase activity +created_by: bf +creation_date: 2011-02-03T04:05:35Z + +[Term] +id: GO:2000362 +name: negative regulation of prostaglandin-E synthase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity." [GOC:BHF] +synonym: "negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of endoperoxide isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of PGE isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of PGE2 isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of PGH-PGE isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of prostaglandin endoperoxide E isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of prostaglandin endoperoxide E2 isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of prostaglandin H-E isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of prostaglandin R-prostaglandin E isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of Prostaglandin-H(2) E-isomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of prostaglandin-H2 E-isomerase activity" EXACT [GOC:obol] +is_a: GO:0043086 ! negative regulation of catalytic activity +is_a: GO:2000361 ! regulation of prostaglandin-E synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0050220 ! prostaglandin-E synthase activity +relationship: negatively_regulates GO:0050220 ! prostaglandin-E synthase activity +created_by: bf +creation_date: 2011-02-03T04:05:39Z + +[Term] +id: GO:2000363 +name: positive regulation of prostaglandin-E synthase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity." [GOC:BHF] +synonym: "positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of endoperoxide isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of PGE isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of PGE2 isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of PGH-PGE isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of prostaglandin endoperoxide E isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of prostaglandin endoperoxide E2 isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of prostaglandin H-E isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of prostaglandin R-prostaglandin E isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of Prostaglandin-H(2) E-isomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of prostaglandin-H2 E-isomerase activity" EXACT [GOC:obol] +is_a: GO:0010912 ! positive regulation of isomerase activity +is_a: GO:2000361 ! regulation of prostaglandin-E synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0050220 ! prostaglandin-E synthase activity +relationship: positively_regulates GO:0050220 ! prostaglandin-E synthase activity +created_by: bf +creation_date: 2011-02-03T04:05:42Z + +[Term] +id: GO:2000367 +name: regulation of acrosomal vesicle exocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis." [GOC:obol] +synonym: "regulation of acrosomal granule exocytosis" RELATED [GOC:obol] +synonym: "regulation of acrosome exocytosis" EXACT [GOC:obol] +is_a: GO:0017158 ! regulation of calcium ion-dependent exocytosis +is_a: GO:0060046 ! regulation of acrosome reaction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060478 ! acrosomal vesicle exocytosis +relationship: regulates GO:0060478 ! acrosomal vesicle exocytosis +created_by: yaf +creation_date: 2011-02-07T11:52:34Z + +[Term] +id: GO:2000368 +name: positive regulation of acrosomal vesicle exocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis." [GOC:obol] +synonym: "positive regulation of acrosomal granule exocytosis" RELATED [GOC:obol] +synonym: "positive regulation of acrosome exocytosis" EXACT [GOC:obol] +is_a: GO:0045956 ! positive regulation of calcium ion-dependent exocytosis +is_a: GO:2000344 ! positive regulation of acrosome reaction +is_a: GO:2000367 ! regulation of acrosomal vesicle exocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060478 ! acrosomal vesicle exocytosis +relationship: positively_regulates GO:0060478 ! acrosomal vesicle exocytosis +created_by: yaf +creation_date: 2011-02-07T11:52:42Z + +[Term] +id: GO:2000369 +name: regulation of clathrin-dependent endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis." [GOC:mah] +synonym: "regulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:obol] +synonym: "regulation of clathrin-dependent endocytosis" EXACT [GOC:obol] +synonym: "regulation of clathrin-mediated endocytosis" EXACT [] +is_a: GO:0048259 ! regulation of receptor-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072583 ! clathrin-dependent endocytosis +relationship: regulates GO:0072583 ! clathrin-dependent endocytosis +created_by: mah +creation_date: 2011-02-09T12:36:18Z + +[Term] +id: GO:2000370 +name: positive regulation of clathrin-dependent endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis." [GOC:BHF, GOC:mah] +synonym: "positive regulation of clathrin coated pit-dependent endocytosis" EXACT [GOC:obol] +synonym: "positive regulation of clathrin-dependent endocytosis" EXACT [GOC:obol] +synonym: "positive regulation of clathrin-mediated endocytosis" EXACT [] +is_a: GO:0048260 ! positive regulation of receptor-mediated endocytosis +is_a: GO:2000369 ! regulation of clathrin-dependent endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072583 ! clathrin-dependent endocytosis +relationship: positively_regulates GO:0072583 ! clathrin-dependent endocytosis +created_by: mah +creation_date: 2011-02-09T12:36:28Z + +[Term] +id: GO:2000371 +name: regulation of DNA topoisomerase (ATP-hydrolyzing) activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity." [GOC:mah] +synonym: "regulation of deoxyribonucleate topoisomerase" RELATED [GOC:obol] +synonym: "regulation of deoxyribonucleic topoisomerase activity" EXACT [GOC:obol] +synonym: "regulation of DNA topoisomerase (ATP-hydrolysing)" RELATED [GOC:obol] +synonym: "regulation of DNA topoisomerase II" RELATED [GOC:obol] +synonym: "regulation of DNA topoisomerase IV activity" EXACT [GOC:obol] +synonym: "regulation of DNA topoisomerase type II activity" EXACT [GOC:obol] +synonym: "regulation of topoisomerase" RELATED [GOC:obol] +synonym: "regulation of topoisomerase II" EXACT [GOC:obol] +synonym: "regulation of type II DNA topoisomerase activity" EXACT [GOC:obol] +is_a: GO:0010911 ! regulation of isomerase activity +is_a: GO:0043462 ! regulation of ATPase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +relationship: regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +created_by: mah +creation_date: 2011-02-09T02:35:27Z + +[Term] +id: GO:2000372 +name: negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity." [GOC:mah] +synonym: "negative regulation of deoxyribonucleate topoisomerase" RELATED [GOC:obol] +synonym: "negative regulation of deoxyribonucleic topoisomerase activity" EXACT [GOC:obol] +synonym: "negative regulation of DNA topoisomerase (ATP-hydrolysing)" RELATED [GOC:obol] +synonym: "negative regulation of DNA topoisomerase II" RELATED [GOC:obol] +synonym: "negative regulation of DNA topoisomerase IV activity" EXACT [GOC:obol] +synonym: "negative regulation of DNA topoisomerase type II activity" EXACT [GOC:obol] +synonym: "negative regulation of topoisomerase" RELATED [GOC:obol] +synonym: "negative regulation of topoisomerase II" EXACT [GOC:obol] +synonym: "negative regulation of type II DNA topoisomerase activity" EXACT [GOC:obol] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:2000371 ! regulation of DNA topoisomerase (ATP-hydrolyzing) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +relationship: negatively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +created_by: mah +creation_date: 2011-02-09T02:35:36Z + +[Term] +id: GO:2000373 +name: positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity." [GOC:mah] +synonym: "positive regulation of deoxyribonucleate topoisomerase" RELATED [GOC:obol] +synonym: "positive regulation of deoxyribonucleic topoisomerase activity" EXACT [GOC:obol] +synonym: "positive regulation of DNA topoisomerase (ATP-hydrolysing)" RELATED [GOC:obol] +synonym: "positive regulation of DNA topoisomerase II" RELATED [GOC:obol] +synonym: "positive regulation of DNA topoisomerase IV activity" EXACT [GOC:obol] +synonym: "positive regulation of DNA topoisomerase type II activity" EXACT [GOC:obol] +synonym: "positive regulation of topoisomerase" RELATED [GOC:obol] +synonym: "positive regulation of topoisomerase II" EXACT [GOC:obol] +synonym: "positive regulation of type II DNA topoisomerase activity" EXACT [GOC:obol] +is_a: GO:0010912 ! positive regulation of isomerase activity +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:2000371 ! regulation of DNA topoisomerase (ATP-hydrolyzing) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +relationship: positively_regulates GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity +created_by: mah +creation_date: 2011-02-09T02:35:43Z + +[Term] +id: GO:2000374 +name: regulation of oxygen metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah] +synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] +synonym: "regulation of oxygen metabolism" EXACT [GOC:obol] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072592 ! oxygen metabolic process +relationship: regulates GO:0072592 ! oxygen metabolic process +created_by: mah +creation_date: 2011-02-11T02:03:32Z + +[Term] +id: GO:2000375 +name: negative regulation of oxygen metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process." [GOC:mah] +synonym: "negative regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] +synonym: "negative regulation of oxygen metabolism" EXACT [GOC:obol] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:2000374 ! regulation of oxygen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072592 ! oxygen metabolic process +relationship: negatively_regulates GO:0072592 ! oxygen metabolic process +created_by: mah +creation_date: 2011-02-11T02:03:44Z + +[Term] +id: GO:2000376 +name: positive regulation of oxygen metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." [GOC:mah] +synonym: "positive regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] +synonym: "positive regulation of oxygen metabolism" EXACT [GOC:obol] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:2000374 ! regulation of oxygen metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072592 ! oxygen metabolic process +relationship: positively_regulates GO:0072592 ! oxygen metabolic process +created_by: mah +creation_date: 2011-02-11T02:03:52Z + +[Term] +id: GO:2000377 +name: regulation of reactive oxygen species metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] +synonym: "regulation of reactive oxygen species metabolism" EXACT [GOC:obol] +synonym: "regulation of ROS metabolic process" EXACT [GOC:obol] +is_a: GO:0031323 ! regulation of cellular metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072593 ! reactive oxygen species metabolic process +relationship: regulates GO:0072593 ! reactive oxygen species metabolic process +created_by: mah +creation_date: 2011-02-11T02:06:36Z + +[Term] +id: GO:2000378 +name: negative regulation of reactive oxygen species metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] +synonym: "negative regulation of reactive oxygen species metabolism" EXACT [GOC:obol] +synonym: "negative regulation of ROS metabolic process" EXACT [GOC:obol] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072593 ! reactive oxygen species metabolic process +relationship: negatively_regulates GO:0072593 ! reactive oxygen species metabolic process +created_by: mah +creation_date: 2011-02-11T02:06:49Z + +[Term] +id: GO:2000379 +name: positive regulation of reactive oxygen species metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] +synonym: "positive regulation of reactive oxygen species metabolism" EXACT [GOC:obol] +synonym: "positive regulation of ROS metabolic process" EXACT [GOC:obol] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:2000377 ! regulation of reactive oxygen species metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072593 ! reactive oxygen species metabolic process +relationship: positively_regulates GO:0072593 ! reactive oxygen species metabolic process +created_by: mah +creation_date: 2011-02-11T02:06:57Z + +[Term] +id: GO:2000380 +name: regulation of mesoderm development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007498 ! mesoderm development +relationship: regulates GO:0007498 ! mesoderm development +created_by: vk +creation_date: 2011-02-15T03:09:46Z + +[Term] +id: GO:2000381 +name: negative regulation of mesoderm development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:2000380 ! regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007498 ! mesoderm development +relationship: negatively_regulates GO:0007498 ! mesoderm development +created_by: vk +creation_date: 2011-02-15T03:10:02Z + +[Term] +id: GO:2000382 +name: positive regulation of mesoderm development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:2000380 ! regulation of mesoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007498 ! mesoderm development +relationship: positively_regulates GO:0007498 ! mesoderm development +created_by: vk +creation_date: 2011-02-15T03:10:12Z + +[Term] +id: GO:2000383 +name: regulation of ectoderm development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007398 ! ectoderm development +relationship: regulates GO:0007398 ! ectoderm development +created_by: vk +creation_date: 2011-02-15T03:17:10Z + +[Term] +id: GO:2000384 +name: negative regulation of ectoderm development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:2000383 ! regulation of ectoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007398 ! ectoderm development +relationship: negatively_regulates GO:0007398 ! ectoderm development +created_by: vk +creation_date: 2011-02-15T03:17:27Z + +[Term] +id: GO:2000385 +name: positive regulation of ectoderm development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:2000383 ! regulation of ectoderm development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007398 ! ectoderm development +relationship: positively_regulates GO:0007398 ! ectoderm development +created_by: vk +creation_date: 2011-02-15T03:17:39Z + +[Term] +id: GO:2000386 +name: positive regulation of ovarian follicle development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ovarian follicle development." [GOC:obol] +synonym: "positive regulation of follicular phase" RELATED [GOC:obol] +is_a: GO:2000196 ! positive regulation of female gonad development +is_a: GO:2000354 ! regulation of ovarian follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001541 ! ovarian follicle development +relationship: positively_regulates GO:0001541 ! ovarian follicle development +created_by: yaf +creation_date: 2011-02-16T02:21:21Z + +[Term] +id: GO:2000387 +name: regulation of antral ovarian follicle growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of antral ovarian follicle growth." [GOC:obol] +is_a: GO:0048638 ! regulation of developmental growth +is_a: GO:2000354 ! regulation of ovarian follicle development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001547 ! antral ovarian follicle growth +relationship: regulates GO:0001547 ! antral ovarian follicle growth +created_by: yaf +creation_date: 2011-02-16T04:53:43Z + +[Term] +id: GO:2000388 +name: positive regulation of antral ovarian follicle growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth." [GOC:obol] +is_a: GO:0048639 ! positive regulation of developmental growth +is_a: GO:2000386 ! positive regulation of ovarian follicle development +is_a: GO:2000387 ! regulation of antral ovarian follicle growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001547 ! antral ovarian follicle growth +relationship: positively_regulates GO:0001547 ! antral ovarian follicle growth +created_by: yaf +creation_date: 2011-02-16T04:54:01Z + +[Term] +id: GO:2000389 +name: regulation of neutrophil extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neutrophil extravasation." [GOC:mah] +is_a: GO:0002691 ! regulation of cellular extravasation +is_a: GO:1902622 ! regulation of neutrophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072672 ! neutrophil extravasation +relationship: regulates GO:0072672 ! neutrophil extravasation +created_by: mah +creation_date: 2011-02-22T11:07:58Z + +[Term] +id: GO:2000390 +name: negative regulation of neutrophil extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation." [GOC:BHF, GOC:mah] +is_a: GO:0002692 ! negative regulation of cellular extravasation +is_a: GO:1902623 ! negative regulation of neutrophil migration +is_a: GO:2000389 ! regulation of neutrophil extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072672 ! neutrophil extravasation +relationship: negatively_regulates GO:0072672 ! neutrophil extravasation +created_by: mah +creation_date: 2011-02-22T11:08:23Z + +[Term] +id: GO:2000391 +name: positive regulation of neutrophil extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil extravasation." [GOC:BHF, GOC:mah] +is_a: GO:0002693 ! positive regulation of cellular extravasation +is_a: GO:1902624 ! positive regulation of neutrophil migration +is_a: GO:2000389 ! regulation of neutrophil extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072672 ! neutrophil extravasation +relationship: positively_regulates GO:0072672 ! neutrophil extravasation +created_by: mah +creation_date: 2011-02-22T11:08:42Z + +[Term] +id: GO:2000392 +name: regulation of lamellipodium morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis." [GOC:mah] +synonym: "regulation of lamellipodium organization" RELATED [GOC:obol] +is_a: GO:0022604 ! regulation of cell morphogenesis +is_a: GO:1902743 ! regulation of lamellipodium organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072673 ! lamellipodium morphogenesis +relationship: regulates GO:0072673 ! lamellipodium morphogenesis +created_by: mah +creation_date: 2011-02-22T11:18:58Z + +[Term] +id: GO:2000393 +name: negative regulation of lamellipodium morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis." [GOC:BHF, GOC:mah] +synonym: "negative regulation of lamellipodium organization" RELATED [GOC:obol] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:1902744 ! negative regulation of lamellipodium organization +is_a: GO:2000392 ! regulation of lamellipodium morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072673 ! lamellipodium morphogenesis +relationship: negatively_regulates GO:0072673 ! lamellipodium morphogenesis +created_by: mah +creation_date: 2011-02-22T11:19:25Z + +[Term] +id: GO:2000394 +name: positive regulation of lamellipodium morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis." [GOC:BHF, GOC:mah] +synonym: "positive regulation of lamellipodium organization" RELATED [GOC:obol] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:1902745 ! positive regulation of lamellipodium organization +is_a: GO:2000392 ! regulation of lamellipodium morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072673 ! lamellipodium morphogenesis +relationship: positively_regulates GO:0072673 ! lamellipodium morphogenesis +created_by: mah +creation_date: 2011-02-22T11:19:45Z + +[Term] +id: GO:2000395 +name: regulation of ubiquitin-dependent endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis." [GOC:mah] +synonym: "regulation of ubiquitin-mediated endocytosis" EXACT [GOC:obol] +is_a: GO:0030100 ! regulation of endocytosis +is_a: GO:0051223 ! regulation of protein transport +is_a: GO:1903827 ! regulation of cellular protein localization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070086 ! ubiquitin-dependent endocytosis +relationship: regulates GO:0070086 ! ubiquitin-dependent endocytosis +created_by: mah +creation_date: 2011-02-22T11:24:52Z + +[Term] +id: GO:2000396 +name: negative regulation of ubiquitin-dependent endocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis." [GOC:mah] +synonym: "negative regulation of ubiquitin-mediated endocytosis" EXACT [GOC:obol] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:0051224 ! negative regulation of protein transport +is_a: GO:1903828 ! negative regulation of cellular protein localization +is_a: GO:2000395 ! regulation of ubiquitin-dependent endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070086 ! ubiquitin-dependent endocytosis +relationship: negatively_regulates GO:0070086 ! ubiquitin-dependent endocytosis +created_by: mah +creation_date: 2011-02-22T11:25:21Z + +[Term] +id: GO:2000397 +name: positive regulation of ubiquitin-dependent endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis." [GOC:mah] +synonym: "positive regulation of ubiquitin-mediated endocytosis" EXACT [GOC:obol] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:0051222 ! positive regulation of protein transport +is_a: GO:1903829 ! positive regulation of cellular protein localization +is_a: GO:2000395 ! regulation of ubiquitin-dependent endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070086 ! ubiquitin-dependent endocytosis +relationship: positively_regulates GO:0070086 ! ubiquitin-dependent endocytosis +created_by: mah +creation_date: 2011-02-22T11:25:42Z + +[Term] +id: GO:2000398 +name: regulation of thymocyte aggregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thymocyte aggregation." [GOC:mah] +synonym: "regulation of immature T cell aggregation" RELATED [GOC:obol] +synonym: "regulation of immature T-cell aggregation" RELATED [GOC:obol] +synonym: "regulation of immature T-lymphocyte aggregation" EXACT [GOC:obol] +synonym: "regulation of T cell precursor aggregation" EXACT [GOC:obol] +synonym: "regulation of thymic lymphocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071594 ! thymocyte aggregation +relationship: regulates GO:0071594 ! thymocyte aggregation +created_by: mah +creation_date: 2011-02-22T02:49:19Z + +[Term] +id: GO:2000399 +name: negative regulation of thymocyte aggregation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation." [GOC:BHF, GOC:mah] +synonym: "negative regulation of immature T cell aggregation" RELATED [GOC:obol] +synonym: "negative regulation of immature T-cell aggregation" RELATED [GOC:obol] +synonym: "negative regulation of immature T-lymphocyte aggregation" EXACT [GOC:obol] +synonym: "negative regulation of T cell precursor aggregation" EXACT [GOC:obol] +synonym: "negative regulation of thymic lymphocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion +is_a: GO:2000398 ! regulation of thymocyte aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071594 ! thymocyte aggregation +relationship: negatively_regulates GO:0071594 ! thymocyte aggregation +created_by: mah +creation_date: 2011-02-22T02:49:44Z + +[Term] +id: GO:2000400 +name: positive regulation of thymocyte aggregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thymocyte aggregation." [GOC:BHF, GOC:mah] +synonym: "positive regulation of immature T cell aggregation" RELATED [GOC:obol] +synonym: "positive regulation of immature T-cell aggregation" RELATED [GOC:obol] +synonym: "positive regulation of immature T-lymphocyte aggregation" EXACT [GOC:obol] +synonym: "positive regulation of T cell precursor aggregation" EXACT [GOC:obol] +synonym: "positive regulation of thymic lymphocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion +is_a: GO:2000398 ! regulation of thymocyte aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071594 ! thymocyte aggregation +relationship: positively_regulates GO:0071594 ! thymocyte aggregation +created_by: mah +creation_date: 2011-02-22T02:50:01Z + +[Term] +id: GO:2000401 +name: regulation of lymphocyte migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072676 ! lymphocyte migration +relationship: regulates GO:0072676 ! lymphocyte migration +created_by: mah +creation_date: 2011-02-23T10:45:19Z + +[Term] +id: GO:2000402 +name: negative regulation of lymphocyte migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:2000401 ! regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072676 ! lymphocyte migration +relationship: negatively_regulates GO:0072676 ! lymphocyte migration +created_by: mah +creation_date: 2011-02-23T10:45:47Z + +[Term] +id: GO:2000403 +name: positive regulation of lymphocyte migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:2000401 ! regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072676 ! lymphocyte migration +relationship: positively_regulates GO:0072676 ! lymphocyte migration +created_by: mah +creation_date: 2011-02-23T10:46:06Z + +[Term] +id: GO:2000404 +name: regulation of T cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah] +synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol] +synonym: "regulation of T-cell migration" EXACT [GOC:obol] +synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000401 ! regulation of lymphocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072678 ! T cell migration +relationship: regulates GO:0072678 ! T cell migration +created_by: mah +creation_date: 2011-02-23T10:48:24Z + +[Term] +id: GO:2000405 +name: negative regulation of T cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah] +synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol] +synonym: "negative regulation of T-cell migration" EXACT [GOC:obol] +synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000402 ! negative regulation of lymphocyte migration +is_a: GO:2000404 ! regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072678 ! T cell migration +relationship: negatively_regulates GO:0072678 ! T cell migration +created_by: mah +creation_date: 2011-02-23T10:48:52Z + +[Term] +id: GO:2000406 +name: positive regulation of T cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah] +synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol] +synonym: "positive regulation of T-cell migration" EXACT [GOC:obol] +synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000403 ! positive regulation of lymphocyte migration +is_a: GO:2000404 ! regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072678 ! T cell migration +relationship: positively_regulates GO:0072678 ! T cell migration +created_by: mah +creation_date: 2011-02-23T10:49:12Z + +[Term] +id: GO:2000407 +name: regulation of T cell extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell extravasation." [GOC:mah] +synonym: "regulation of T lymphocyte extravasation" EXACT [GOC:obol] +synonym: "regulation of T-cell extravasation" EXACT [GOC:obol] +synonym: "regulation of T-lymphocyte extravasation" EXACT [GOC:obol] +is_a: GO:0002691 ! regulation of cellular extravasation +is_a: GO:2000404 ! regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072683 ! T cell extravasation +relationship: regulates GO:0072683 ! T cell extravasation +created_by: mah +creation_date: 2011-02-23T10:51:58Z + +[Term] +id: GO:2000408 +name: negative regulation of T cell extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation." [GOC:BHF, GOC:mah] +synonym: "negative regulation of T lymphocyte extravasation" EXACT [GOC:obol] +synonym: "negative regulation of T-cell extravasation" EXACT [GOC:obol] +synonym: "negative regulation of T-lymphocyte extravasation" EXACT [GOC:obol] +is_a: GO:0002692 ! negative regulation of cellular extravasation +is_a: GO:2000405 ! negative regulation of T cell migration +is_a: GO:2000407 ! regulation of T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072683 ! T cell extravasation +relationship: negatively_regulates GO:0072683 ! T cell extravasation +created_by: mah +creation_date: 2011-02-23T10:52:28Z + +[Term] +id: GO:2000409 +name: positive regulation of T cell extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell extravasation." [GOC:BHF, GOC:mah] +synonym: "positive regulation of T lymphocyte extravasation" EXACT [GOC:obol] +synonym: "positive regulation of T-cell extravasation" EXACT [GOC:obol] +synonym: "positive regulation of T-lymphocyte extravasation" EXACT [GOC:obol] +is_a: GO:0002693 ! positive regulation of cellular extravasation +is_a: GO:2000406 ! positive regulation of T cell migration +is_a: GO:2000407 ! regulation of T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072683 ! T cell extravasation +relationship: positively_regulates GO:0072683 ! T cell extravasation +created_by: mah +creation_date: 2011-02-23T10:52:50Z + +[Term] +id: GO:2000410 +name: regulation of thymocyte migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thymocyte migration." [GOC:mah] +synonym: "regulation of immature T cell migration" RELATED [GOC:obol] +synonym: "regulation of immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "regulation of immature T-cell migration" RELATED [GOC:obol] +synonym: "regulation of immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "regulation of thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000404 ! regulation of T cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072679 ! thymocyte migration +relationship: regulates GO:0072679 ! thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:33:32Z + +[Term] +id: GO:2000411 +name: negative regulation of thymocyte migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration." [GOC:mah] +synonym: "negative regulation of immature T cell migration" RELATED [GOC:obol] +synonym: "negative regulation of immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "negative regulation of immature T-cell migration" RELATED [GOC:obol] +synonym: "negative regulation of immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "negative regulation of thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000405 ! negative regulation of T cell migration +is_a: GO:2000410 ! regulation of thymocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072679 ! thymocyte migration +relationship: negatively_regulates GO:0072679 ! thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:34:01Z + +[Term] +id: GO:2000412 +name: positive regulation of thymocyte migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thymocyte migration." [GOC:mah] +synonym: "positive regulation of immature T cell migration" RELATED [GOC:obol] +synonym: "positive regulation of immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "positive regulation of immature T-cell migration" RELATED [GOC:obol] +synonym: "positive regulation of immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "positive regulation of thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000406 ! positive regulation of T cell migration +is_a: GO:2000410 ! regulation of thymocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072679 ! thymocyte migration +relationship: positively_regulates GO:0072679 ! thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:34:23Z + +[Term] +id: GO:2000413 +name: regulation of fibronectin-dependent thymocyte migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration." [GOC:mah] +synonym: "regulation of fibronectin-dependent immature T cell migration" RELATED [GOC:obol] +synonym: "regulation of fibronectin-dependent immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "regulation of fibronectin-dependent immature T-cell migration" RELATED [GOC:obol] +synonym: "regulation of fibronectin-dependent immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "regulation of fibronectin-dependent thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000410 ! regulation of thymocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072681 ! fibronectin-dependent thymocyte migration +relationship: regulates GO:0072681 ! fibronectin-dependent thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:38:08Z + +[Term] +id: GO:2000414 +name: negative regulation of fibronectin-dependent thymocyte migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration." [GOC:BHF, GOC:mah] +synonym: "negative regulation of fibronectin-dependent immature T cell migration" RELATED [GOC:obol] +synonym: "negative regulation of fibronectin-dependent immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "negative regulation of fibronectin-dependent immature T-cell migration" RELATED [GOC:obol] +synonym: "negative regulation of fibronectin-dependent immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "negative regulation of fibronectin-dependent thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000411 ! negative regulation of thymocyte migration +is_a: GO:2000413 ! regulation of fibronectin-dependent thymocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072681 ! fibronectin-dependent thymocyte migration +relationship: negatively_regulates GO:0072681 ! fibronectin-dependent thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:38:37Z + +[Term] +id: GO:2000415 +name: positive regulation of fibronectin-dependent thymocyte migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration." [GOC:BHF, GOC:mah] +synonym: "positive regulation of fibronectin-dependent immature T cell migration" RELATED [GOC:obol] +synonym: "positive regulation of fibronectin-dependent immature T lymphocyte migration" RELATED [GOC:obol] +synonym: "positive regulation of fibronectin-dependent immature T-cell migration" RELATED [GOC:obol] +synonym: "positive regulation of fibronectin-dependent immature T-lymphocyte migration" RELATED [GOC:obol] +synonym: "positive regulation of fibronectin-dependent thymic lymphocyte migration" EXACT [GOC:obol] +is_a: GO:2000412 ! positive regulation of thymocyte migration +is_a: GO:2000413 ! regulation of fibronectin-dependent thymocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072681 ! fibronectin-dependent thymocyte migration +relationship: positively_regulates GO:0072681 ! fibronectin-dependent thymocyte migration +created_by: mah +creation_date: 2011-02-23T01:39:00Z + +[Term] +id: GO:2000416 +name: regulation of eosinophil migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eosinophil migration." [GOC:mah] +is_a: GO:0002685 ! regulation of leukocyte migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072677 ! eosinophil migration +relationship: regulates GO:0072677 ! eosinophil migration +created_by: mah +creation_date: 2011-02-23T01:43:23Z + +[Term] +id: GO:2000417 +name: negative regulation of eosinophil migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration." [GOC:mah] +is_a: GO:0002686 ! negative regulation of leukocyte migration +is_a: GO:2000416 ! regulation of eosinophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072677 ! eosinophil migration +relationship: negatively_regulates GO:0072677 ! eosinophil migration +created_by: mah +creation_date: 2011-02-23T01:43:52Z + +[Term] +id: GO:2000418 +name: positive regulation of eosinophil migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil migration." [GOC:mah] +is_a: GO:0002687 ! positive regulation of leukocyte migration +is_a: GO:2000416 ! regulation of eosinophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072677 ! eosinophil migration +relationship: positively_regulates GO:0072677 ! eosinophil migration +created_by: mah +creation_date: 2011-02-23T01:44:14Z + +[Term] +id: GO:2000419 +name: regulation of eosinophil extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eosinophil extravasation." [GOC:mah] +is_a: GO:0002691 ! regulation of cellular extravasation +is_a: GO:2000416 ! regulation of eosinophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072682 ! eosinophil extravasation +relationship: regulates GO:0072682 ! eosinophil extravasation +created_by: mah +creation_date: 2011-02-23T01:46:47Z + +[Term] +id: GO:2000420 +name: negative regulation of eosinophil extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation." [GOC:BHF, GOC:mah] +is_a: GO:0002692 ! negative regulation of cellular extravasation +is_a: GO:2000417 ! negative regulation of eosinophil migration +is_a: GO:2000419 ! regulation of eosinophil extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072682 ! eosinophil extravasation +relationship: negatively_regulates GO:0072682 ! eosinophil extravasation +created_by: mah +creation_date: 2011-02-23T01:47:18Z + +[Term] +id: GO:2000421 +name: positive regulation of eosinophil extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil extravasation." [GOC:BHF, GOC:mah] +is_a: GO:0002693 ! positive regulation of cellular extravasation +is_a: GO:2000418 ! positive regulation of eosinophil migration +is_a: GO:2000419 ! regulation of eosinophil extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072682 ! eosinophil extravasation +relationship: positively_regulates GO:0072682 ! eosinophil extravasation +created_by: mah +creation_date: 2011-02-23T01:47:42Z + +[Term] +id: GO:2000422 +name: regulation of eosinophil chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of eosinophil chemotaxis." [GOC:obol] +is_a: GO:0071622 ! regulation of granulocyte chemotaxis +is_a: GO:2000416 ! regulation of eosinophil migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048245 ! eosinophil chemotaxis +relationship: regulates GO:0048245 ! eosinophil chemotaxis +created_by: bf +creation_date: 2011-02-24T01:16:44Z + +[Term] +id: GO:2000423 +name: negative regulation of eosinophil chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis." [GOC:obol] +is_a: GO:0071623 ! negative regulation of granulocyte chemotaxis +is_a: GO:2000417 ! negative regulation of eosinophil migration +is_a: GO:2000422 ! regulation of eosinophil chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048245 ! eosinophil chemotaxis +relationship: negatively_regulates GO:0048245 ! eosinophil chemotaxis +created_by: bf +creation_date: 2011-02-24T01:17:12Z + +[Term] +id: GO:2000424 +name: positive regulation of eosinophil chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis." [GOC:obol] +is_a: GO:0071624 ! positive regulation of granulocyte chemotaxis +is_a: GO:2000418 ! positive regulation of eosinophil migration +is_a: GO:2000422 ! regulation of eosinophil chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048245 ! eosinophil chemotaxis +relationship: positively_regulates GO:0048245 ! eosinophil chemotaxis +created_by: bf +creation_date: 2011-02-24T01:17:35Z + +[Term] +id: GO:2000425 +name: regulation of apoptotic cell clearance +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic cell clearance." [GOC:obol] +synonym: "regulation of apoptotic cell removal" EXACT [GOC:obol] +synonym: "regulation of efferocytosis" EXACT [GOC:obol] +synonym: "regulation of programmed cell clearance" EXACT [GOC:obol] +is_a: GO:0050764 ! regulation of phagocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043277 ! apoptotic cell clearance +relationship: regulates GO:0043277 ! apoptotic cell clearance +created_by: bf +creation_date: 2011-02-25T11:50:11Z + +[Term] +id: GO:2000426 +name: negative regulation of apoptotic cell clearance +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance." [GOC:obol] +synonym: "negative regulation of apoptotic cell removal" EXACT [GOC:obol] +synonym: "negative regulation of efferocytosis" EXACT [GOC:obol] +synonym: "negative regulation of programmed cell clearance" EXACT [GOC:obol] +is_a: GO:0050765 ! negative regulation of phagocytosis +is_a: GO:2000425 ! regulation of apoptotic cell clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043277 ! apoptotic cell clearance +relationship: negatively_regulates GO:0043277 ! apoptotic cell clearance +created_by: bf +creation_date: 2011-02-25T11:50:39Z + +[Term] +id: GO:2000427 +name: positive regulation of apoptotic cell clearance +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance." [GOC:obol] +synonym: "positive regulation of apoptotic cell removal" EXACT [GOC:obol] +synonym: "positive regulation of efferocytosis" EXACT [GOC:obol] +synonym: "positive regulation of programmed cell clearance" EXACT [GOC:obol] +is_a: GO:0050766 ! positive regulation of phagocytosis +is_a: GO:2000425 ! regulation of apoptotic cell clearance +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043277 ! apoptotic cell clearance +relationship: positively_regulates GO:0043277 ! apoptotic cell clearance +created_by: bf +creation_date: 2011-02-25T11:50:59Z + +[Term] +id: GO:2000428 +name: regulation of neutrophil aggregation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neutrophil aggregation." [GOC:BHF] +synonym: "regulation of neutrocyte aggregation" EXACT [GOC:obol] +synonym: "regulation of neutrophil leucocyte aggregation" EXACT [GOC:obol] +synonym: "regulation of neutrophilic leukocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070488 ! neutrophil aggregation +relationship: regulates GO:0070488 ! neutrophil aggregation +created_by: ebc +creation_date: 2011-02-28T05:18:54Z + +[Term] +id: GO:2000429 +name: negative regulation of neutrophil aggregation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation." [GOC:BHF] +synonym: "negative regulation of neutrocyte aggregation" EXACT [GOC:obol] +synonym: "negative regulation of neutrophil leucocyte aggregation" EXACT [GOC:obol] +synonym: "negative regulation of neutrophilic leukocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion +is_a: GO:2000428 ! regulation of neutrophil aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070488 ! neutrophil aggregation +relationship: negatively_regulates GO:0070488 ! neutrophil aggregation +created_by: ebc +creation_date: 2011-02-28T05:19:28Z + +[Term] +id: GO:2000430 +name: positive regulation of neutrophil aggregation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neutrophil aggregation." [GOC:BHF] +synonym: "positive regulation of neutrocyte aggregation" EXACT [GOC:obol] +synonym: "positive regulation of neutrophil leucocyte aggregation" EXACT [GOC:obol] +synonym: "positive regulation of neutrophilic leukocyte aggregation" EXACT [GOC:obol] +is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion +is_a: GO:2000428 ! regulation of neutrophil aggregation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070488 ! neutrophil aggregation +relationship: positively_regulates GO:0070488 ! neutrophil aggregation +created_by: ebc +creation_date: 2011-02-28T05:19:51Z + +[Term] +id: GO:2000431 +name: regulation of cytokinesis, actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly." [GOC:obol] +synonym: "regulation of contractile ring assembly" EXACT [GOC:obol] +is_a: GO:0032954 ! regulation of cytokinetic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0110020 ! regulation of actomyosin structure organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000915 ! actomyosin contractile ring assembly +relationship: regulates GO:0000915 ! actomyosin contractile ring assembly +created_by: vw +creation_date: 2011-03-03T12:17:41Z + +[Term] +id: GO:2000432 +name: negative regulation of cytokinesis, actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly." [GOC:obol] +synonym: "negative regulation of contractile ring assembly" EXACT [GOC:obol] +is_a: GO:0032466 ! negative regulation of cytokinesis +is_a: GO:0051494 ! negative regulation of cytoskeleton organization +is_a: GO:2000431 ! regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000915 ! actomyosin contractile ring assembly +relationship: negatively_regulates GO:0000915 ! actomyosin contractile ring assembly +created_by: vw +creation_date: 2011-03-03T12:18:16Z + +[Term] +id: GO:2000433 +name: positive regulation of cytokinesis, actomyosin contractile ring assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly." [GOC:obol] +synonym: "positive regulation of contractile ring assembly" EXACT [GOC:obol] +is_a: GO:0032467 ! positive regulation of cytokinesis +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051495 ! positive regulation of cytoskeleton organization +is_a: GO:2000431 ! regulation of cytokinesis, actomyosin contractile ring assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000915 ! actomyosin contractile ring assembly +relationship: positively_regulates GO:0000915 ! actomyosin contractile ring assembly +created_by: vw +creation_date: 2011-03-03T12:18:43Z + +[Term] +id: GO:2000434 +name: regulation of protein neddylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein neddylation." [GOC:obol] +synonym: "regulation of RUB1-protein conjugation" EXACT [GOC:obol] +is_a: GO:1903320 ! regulation of protein modification by small protein conjugation or removal +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045116 ! protein neddylation +relationship: regulates GO:0045116 ! protein neddylation +created_by: vw +creation_date: 2011-03-03T02:05:22Z + +[Term] +id: GO:2000435 +name: negative regulation of protein neddylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation." [GOC:obol] +synonym: "negative regulation of RUB1-protein conjugation" EXACT [GOC:obol] +is_a: GO:1903321 ! negative regulation of protein modification by small protein conjugation or removal +is_a: GO:2000434 ! regulation of protein neddylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045116 ! protein neddylation +relationship: negatively_regulates GO:0045116 ! protein neddylation +created_by: vw +creation_date: 2011-03-03T02:05:56Z + +[Term] +id: GO:2000436 +name: positive regulation of protein neddylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein neddylation." [GOC:obol] +synonym: "positive regulation of RUB1-protein conjugation" EXACT [GOC:obol] +is_a: GO:1903322 ! positive regulation of protein modification by small protein conjugation or removal +is_a: GO:2000434 ! regulation of protein neddylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045116 ! protein neddylation +relationship: positively_regulates GO:0045116 ! protein neddylation +created_by: vw +creation_date: 2011-03-03T02:06:19Z + +[Term] +id: GO:2000437 +name: regulation of monocyte extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of monocyte extravasation." [GOC:obol] +is_a: GO:0002691 ! regulation of cellular extravasation +is_a: GO:0071675 ! regulation of mononuclear cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035696 ! monocyte extravasation +relationship: regulates GO:0035696 ! monocyte extravasation +created_by: bf +creation_date: 2011-03-04T10:24:08Z + +[Term] +id: GO:2000438 +name: negative regulation of monocyte extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation." [GOC:obol] +is_a: GO:0002692 ! negative regulation of cellular extravasation +is_a: GO:0071676 ! negative regulation of mononuclear cell migration +is_a: GO:2000437 ! regulation of monocyte extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035696 ! monocyte extravasation +relationship: negatively_regulates GO:0035696 ! monocyte extravasation +created_by: bf +creation_date: 2011-03-04T10:24:44Z + +[Term] +id: GO:2000439 +name: positive regulation of monocyte extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of monocyte extravasation." [GOC:obol] +is_a: GO:0002693 ! positive regulation of cellular extravasation +is_a: GO:0071677 ! positive regulation of mononuclear cell migration +is_a: GO:2000437 ! regulation of monocyte extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035696 ! monocyte extravasation +relationship: positively_regulates GO:0035696 ! monocyte extravasation +created_by: bf +creation_date: 2011-03-04T10:25:11Z + +[Term] +id: GO:2000440 +name: regulation of toll-like receptor 15 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway." [GOC:obol] +synonym: "regulation of TLR15 signaling pathway" EXACT [GOC:obol] +synonym: "regulation of toll-like receptor 15 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035681 ! toll-like receptor 15 signaling pathway +relationship: regulates GO:0035681 ! toll-like receptor 15 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:28:24Z + +[Term] +id: GO:2000441 +name: negative regulation of toll-like receptor 15 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway." [GOC:obol] +synonym: "negative regulation of TLR15 signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of toll-like receptor 15 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:2000440 ! regulation of toll-like receptor 15 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035681 ! toll-like receptor 15 signaling pathway +relationship: negatively_regulates GO:0035681 ! toll-like receptor 15 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:29:04Z + +[Term] +id: GO:2000442 +name: positive regulation of toll-like receptor 15 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway." [GOC:obol] +synonym: "positive regulation of TLR15 signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of toll-like receptor 15 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:2000440 ! regulation of toll-like receptor 15 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035681 ! toll-like receptor 15 signaling pathway +relationship: positively_regulates GO:0035681 ! toll-like receptor 15 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:29:36Z + +[Term] +id: GO:2000443 +name: regulation of toll-like receptor 21 signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway." [GOC:obol] +synonym: "regulation of TLR21 signaling pathway" EXACT [GOC:obol] +synonym: "regulation of toll-like receptor 21 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034121 ! regulation of toll-like receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035682 ! toll-like receptor 21 signaling pathway +relationship: regulates GO:0035682 ! toll-like receptor 21 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:31:48Z + +[Term] +id: GO:2000444 +name: negative regulation of toll-like receptor 21 signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway." [GOC:obol] +synonym: "negative regulation of TLR21 signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of toll-like receptor 21 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034122 ! negative regulation of toll-like receptor signaling pathway +is_a: GO:2000443 ! regulation of toll-like receptor 21 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035682 ! toll-like receptor 21 signaling pathway +relationship: negatively_regulates GO:0035682 ! toll-like receptor 21 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:32:29Z + +[Term] +id: GO:2000445 +name: positive regulation of toll-like receptor 21 signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway." [GOC:obol] +synonym: "positive regulation of TLR21 signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of toll-like receptor 21 signalling pathway" EXACT [GOC:mah] +is_a: GO:0034123 ! positive regulation of toll-like receptor signaling pathway +is_a: GO:2000443 ! regulation of toll-like receptor 21 signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035682 ! toll-like receptor 21 signaling pathway +relationship: positively_regulates GO:0035682 ! toll-like receptor 21 signaling pathway +created_by: bf +creation_date: 2011-03-04T10:33:00Z + +[Term] +id: GO:2000446 +name: regulation of macrophage migration inhibitory factor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway." [GOC:obol] +synonym: "regulation of macrophage migration inhibitory factor signalling pathway" EXACT [GOC:mah] +synonym: "regulation of MIF signaling pathway" EXACT [GOC:obol] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +relationship: regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +created_by: bf +creation_date: 2011-03-04T10:37:39Z + +[Term] +id: GO:2000447 +name: negative regulation of macrophage migration inhibitory factor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway." [GOC:obol] +synonym: "negative regulation of macrophage migration inhibitory factor signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of MIF signaling pathway" EXACT [GOC:obol] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:2000446 ! regulation of macrophage migration inhibitory factor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +relationship: negatively_regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +created_by: bf +creation_date: 2011-03-04T10:38:15Z + +[Term] +id: GO:2000448 +name: positive regulation of macrophage migration inhibitory factor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway." [GOC:obol] +synonym: "positive regulation of macrophage migration inhibitory factor signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of MIF signaling pathway" EXACT [GOC:obol] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:2000446 ! regulation of macrophage migration inhibitory factor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +relationship: positively_regulates GO:0035691 ! macrophage migration inhibitory factor signaling pathway +created_by: bf +creation_date: 2011-03-04T10:38:43Z + +[Term] +id: GO:2000449 +name: regulation of CD8-positive, alpha-beta T cell extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation." [GOC:obol] +is_a: GO:2000407 ! regulation of T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +relationship: regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:41:03Z + +[Term] +id: GO:2000450 +name: negative regulation of CD8-positive, alpha-beta T cell extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation." [GOC:obol] +is_a: GO:2000408 ! negative regulation of T cell extravasation +is_a: GO:2000449 ! regulation of CD8-positive, alpha-beta T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +relationship: negatively_regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:41:43Z + +[Term] +id: GO:2000451 +name: positive regulation of CD8-positive, alpha-beta T cell extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation." [GOC:obol] +is_a: GO:2000409 ! positive regulation of T cell extravasation +is_a: GO:2000449 ! regulation of CD8-positive, alpha-beta T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +relationship: positively_regulates GO:0035697 ! CD8-positive, alpha-beta T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:42:14Z + +[Term] +id: GO:2000452 +name: regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation." [GOC:obol] +is_a: GO:2000449 ! regulation of CD8-positive, alpha-beta T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +relationship: regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:44:39Z + +[Term] +id: GO:2000453 +name: negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation." [GOC:obol] +is_a: GO:2000450 ! negative regulation of CD8-positive, alpha-beta T cell extravasation +is_a: GO:2000452 ! regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +relationship: negatively_regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:45:20Z + +[Term] +id: GO:2000454 +name: positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation." [GOC:obol] +is_a: GO:2000451 ! positive regulation of CD8-positive, alpha-beta T cell extravasation +is_a: GO:2000452 ! regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +relationship: positively_regulates GO:0035698 ! CD8-positive, alpha-beta cytotoxic T cell extravasation +created_by: bf +creation_date: 2011-03-04T10:45:52Z + +[Term] +id: GO:2000455 +name: regulation of T-helper 17 cell extravasation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation." [GOC:obol] +is_a: GO:2000449 ! regulation of CD8-positive, alpha-beta T cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035699 ! T-helper 17 cell extravasation +relationship: regulates GO:0035699 ! T-helper 17 cell extravasation +created_by: bf +creation_date: 2011-03-04T10:49:51Z + +[Term] +id: GO:2000456 +name: negative regulation of T-helper 17 cell extravasation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation." [GOC:obol] +is_a: GO:2000450 ! negative regulation of CD8-positive, alpha-beta T cell extravasation +is_a: GO:2000455 ! regulation of T-helper 17 cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035699 ! T-helper 17 cell extravasation +relationship: negatively_regulates GO:0035699 ! T-helper 17 cell extravasation +created_by: bf +creation_date: 2011-03-04T10:50:29Z + +[Term] +id: GO:2000457 +name: positive regulation of T-helper 17 cell extravasation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation." [GOC:obol] +is_a: GO:2000451 ! positive regulation of CD8-positive, alpha-beta T cell extravasation +is_a: GO:2000455 ! regulation of T-helper 17 cell extravasation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035699 ! T-helper 17 cell extravasation +relationship: positively_regulates GO:0035699 ! T-helper 17 cell extravasation +created_by: bf +creation_date: 2011-03-04T10:51:00Z + +[Term] +id: GO:2000458 +name: regulation of astrocyte chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of astrocyte chemotaxis." [GOC:obol] +is_a: GO:0050920 ! regulation of chemotaxis +is_a: GO:1903975 ! regulation of glial cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035700 ! astrocyte chemotaxis +relationship: regulates GO:0035700 ! astrocyte chemotaxis +created_by: bf +creation_date: 2011-03-04T10:53:50Z + +[Term] +id: GO:2000459 +name: negative regulation of astrocyte chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis." [GOC:obol] +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:1903976 ! negative regulation of glial cell migration +is_a: GO:2000458 ! regulation of astrocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035700 ! astrocyte chemotaxis +relationship: negatively_regulates GO:0035700 ! astrocyte chemotaxis +created_by: bf +creation_date: 2011-03-04T10:54:28Z + +[Term] +id: GO:2000460 +name: obsolete regulation of eukaryotic cell surface binding +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of eukaryotic cell surface binding." [GOC:obol] +comment: This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion. +synonym: "regulation of eukaryotic cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0031347 +consider: GO:1900120 +created_by: yaf +creation_date: 2011-03-04T11:59:52Z + +[Term] +id: GO:2000461 +name: obsolete negative regulation of eukaryotic cell surface binding +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic cell surface binding." [GOC:obol] +comment: This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion. +synonym: "negative regulation of eukaryotic cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0031347 +consider: GO:1900121 +created_by: yaf +creation_date: 2011-03-04T12:00:26Z + +[Term] +id: GO:2000462 +name: obsolete positive regulation of eukaryotic cell surface binding +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of eukaryotic cell surface binding." [GOC:obol] +comment: This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion. +synonym: "positive regulation of eukaryotic cell surface binding" EXACT [] +is_obsolete: true +consider: GO:0031347 +consider: GO:1900122 +created_by: yaf +creation_date: 2011-03-04T12:00:49Z + +[Term] +id: GO:2000463 +name: positive regulation of excitatory postsynaptic potential +namespace: biological_process +def: "Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential." [GOC:bf, GOC:BHF] +synonym: "positive regulation of EPSP" RELATED [GOC:bf, GOC:obol] +synonym: "positive regulation of excitatory post-synaptic membrane potential" EXACT [] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0031646 ! positive regulation of nervous system process +is_a: GO:0050806 ! positive regulation of synaptic transmission +is_a: GO:0098815 ! modulation of excitatory postsynaptic potential +intersection_of: GO:0050789 ! regulation of biological process +intersection_of: positively_regulates GO:0060079 ! excitatory postsynaptic potential +relationship: positively_regulates GO:0060079 ! excitatory postsynaptic potential +created_by: rl +creation_date: 2011-03-04T02:43:32Z + +[Term] +id: GO:2000464 +name: positive regulation of astrocyte chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis." [GOC:obol] +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:1903977 ! positive regulation of glial cell migration +is_a: GO:2000458 ! regulation of astrocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035700 ! astrocyte chemotaxis +relationship: positively_regulates GO:0035700 ! astrocyte chemotaxis +created_by: bf +creation_date: 2011-03-04T04:43:29Z + +[Term] +id: GO:2000465 +name: regulation of glycogen (starch) synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] +synonym: "regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] +synonym: "regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +synonym: "regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] +synonym: "regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] +synonym: "regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] +synonym: "regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004373 ! glycogen (starch) synthase activity +relationship: regulates GO:0004373 ! glycogen (starch) synthase activity +created_by: yaf +creation_date: 2011-03-07T04:12:35Z + +[Term] +id: GO:2000466 +name: negative regulation of glycogen (starch) synthase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] +synonym: "negative regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] +synonym: "negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:2000465 ! regulation of glycogen (starch) synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004373 ! glycogen (starch) synthase activity +relationship: negatively_regulates GO:0004373 ! glycogen (starch) synthase activity +created_by: yaf +creation_date: 2011-03-07T04:13:14Z + +[Term] +id: GO:2000467 +name: positive regulation of glycogen (starch) synthase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] +synonym: "positive regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] +synonym: "positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] +synonym: "positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:2000465 ! regulation of glycogen (starch) synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004373 ! glycogen (starch) synthase activity +relationship: positively_regulates GO:0004373 ! glycogen (starch) synthase activity +created_by: yaf +creation_date: 2011-03-07T04:13:41Z + +[Term] +id: GO:2000468 +name: regulation of peroxidase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peroxidase activity." [GOC:obol] +synonym: "regulation of donor:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:obol] +synonym: "regulation of oxyperoxidase activity" EXACT [GOC:obol] +synonym: "regulation of peroxidase reaction" EXACT [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004601 ! peroxidase activity +relationship: regulates GO:0004601 ! peroxidase activity +created_by: bf +creation_date: 2011-03-08T02:18:18Z + +[Term] +id: GO:2000469 +name: negative regulation of peroxidase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity." [GOC:obol] +synonym: "negative regulation of donor:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:obol] +synonym: "negative regulation of oxyperoxidase activity" EXACT [GOC:obol] +synonym: "negative regulation of peroxidase reaction" EXACT [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:2000468 ! regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004601 ! peroxidase activity +relationship: negatively_regulates GO:0004601 ! peroxidase activity +created_by: bf +creation_date: 2011-03-08T02:18:59Z + +[Term] +id: GO:2000470 +name: positive regulation of peroxidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peroxidase activity." [GOC:obol] +synonym: "positive regulation of donor:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:obol] +synonym: "positive regulation of oxyperoxidase activity" EXACT [GOC:obol] +synonym: "positive regulation of peroxidase reaction" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0051353 ! positive regulation of oxidoreductase activity +is_a: GO:2000468 ! regulation of peroxidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004601 ! peroxidase activity +relationship: positively_regulates GO:0004601 ! peroxidase activity +created_by: bf +creation_date: 2011-03-08T02:19:25Z + +[Term] +id: GO:2000471 +name: regulation of hematopoietic stem cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] +synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol] +is_a: GO:0030334 ! regulation of cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035701 ! hematopoietic stem cell migration +relationship: regulates GO:0035701 ! hematopoietic stem cell migration +created_by: bf +creation_date: 2011-03-09T09:34:08Z + +[Term] +id: GO:2000472 +name: negative regulation of hematopoietic stem cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] +synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:2000471 ! regulation of hematopoietic stem cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035701 ! hematopoietic stem cell migration +relationship: negatively_regulates GO:0035701 ! hematopoietic stem cell migration +created_by: bf +creation_date: 2011-03-09T09:34:54Z + +[Term] +id: GO:2000473 +name: positive regulation of hematopoietic stem cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] +synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:2000471 ! regulation of hematopoietic stem cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035701 ! hematopoietic stem cell migration +relationship: positively_regulates GO:0035701 ! hematopoietic stem cell migration +created_by: bf +creation_date: 2011-03-09T09:35:25Z + +[Term] +id: GO:2000474 +name: regulation of opioid receptor signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway." [GOC:obol] +synonym: "regulation of opioid receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0008277 ! regulation of G protein-coupled receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038003 ! opioid receptor signaling pathway +relationship: regulates GO:0038003 ! opioid receptor signaling pathway +created_by: bf +creation_date: 2011-03-09T09:40:19Z + +[Term] +id: GO:2000475 +name: negative regulation of opioid receptor signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway." [GOC:obol] +synonym: "negative regulation of opioid receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045744 ! negative regulation of G protein-coupled receptor signaling pathway +is_a: GO:2000474 ! regulation of opioid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038003 ! opioid receptor signaling pathway +relationship: negatively_regulates GO:0038003 ! opioid receptor signaling pathway +created_by: bf +creation_date: 2011-03-09T09:41:03Z + +[Term] +id: GO:2000476 +name: positive regulation of opioid receptor signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway." [GOC:obol] +synonym: "positive regulation of opioid receptor signalling pathway" EXACT [GOC:mah] +is_a: GO:0045745 ! positive regulation of G protein-coupled receptor signaling pathway +is_a: GO:2000474 ! regulation of opioid receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038003 ! opioid receptor signaling pathway +relationship: positively_regulates GO:0038003 ! opioid receptor signaling pathway +created_by: bf +creation_date: 2011-03-09T09:41:35Z + +[Term] +id: GO:2000477 +name: regulation of metanephric glomerular visceral epithelial cell development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development." [GOC:obol] +synonym: "regulation of metanephric podocyte development" RELATED [GOC:obol] +is_a: GO:0060284 ! regulation of cell development +is_a: GO:0072298 ! regulation of metanephric glomerulus development +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072249 ! metanephric glomerular visceral epithelial cell development +relationship: regulates GO:0072249 ! metanephric glomerular visceral epithelial cell development +created_by: yaf +creation_date: 2011-03-09T05:16:40Z + +[Term] +id: GO:2000478 +name: positive regulation of metanephric glomerular visceral epithelial cell development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development." [GOC:obol] +synonym: "positive regulation of metanephric podocyte development" RELATED [GOC:obol] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0072300 ! positive regulation of metanephric glomerulus development +is_a: GO:2000477 ! regulation of metanephric glomerular visceral epithelial cell development +is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072249 ! metanephric glomerular visceral epithelial cell development +relationship: positively_regulates GO:0072249 ! metanephric glomerular visceral epithelial cell development +created_by: yaf +creation_date: 2011-03-09T05:17:26Z + +[Term] +id: GO:2000479 +name: regulation of cAMP-dependent protein kinase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] +synonym: "regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "regulation of AMPK" RELATED [GOC:obol] +synonym: "regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] +synonym: "regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] +synonym: "regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "regulation of PKA" RELATED [GOC:obol] +synonym: "regulation of PKA C" RELATED [GOC:obol] +synonym: "regulation of protein kinase A activity" RELATED [GOC:obol] +synonym: "regulation of STK22" RELATED [GOC:obol] +is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004691 ! cAMP-dependent protein kinase activity +relationship: regulates GO:0004691 ! cAMP-dependent protein kinase activity +created_by: yaf +creation_date: 2011-03-10T11:13:01Z + +[Term] +id: GO:2000480 +name: negative regulation of cAMP-dependent protein kinase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] +synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "negative regulation of AMPK" RELATED [GOC:obol] +synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] +synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] +synonym: "negative regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "negative regulation of PKA" RELATED [GOC:obol] +synonym: "negative regulation of PKA C" RELATED [GOC:obol] +synonym: "negative regulation of protein kinase A activity" RELATED [GOC:obol] +synonym: "negative regulation of STK22" RELATED [GOC:obol] +is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity +is_a: GO:2000479 ! regulation of cAMP-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004691 ! cAMP-dependent protein kinase activity +relationship: negatively_regulates GO:0004691 ! cAMP-dependent protein kinase activity +created_by: yaf +creation_date: 2011-03-10T11:13:45Z + +[Term] +id: GO:2000481 +name: positive regulation of cAMP-dependent protein kinase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] +synonym: "positive regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "positive regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "positive regulation of AMPK" RELATED [GOC:obol] +synonym: "positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] +synonym: "positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] +synonym: "positive regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] +synonym: "positive regulation of PKA" RELATED [GOC:obol] +synonym: "positive regulation of PKA C" RELATED [GOC:obol] +synonym: "positive regulation of protein kinase A activity" RELATED [GOC:obol] +synonym: "positive regulation of STK22" RELATED [GOC:obol] +is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity +is_a: GO:2000479 ! regulation of cAMP-dependent protein kinase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004691 ! cAMP-dependent protein kinase activity +relationship: positively_regulates GO:0004691 ! cAMP-dependent protein kinase activity +created_by: yaf +creation_date: 2011-03-10T11:14:17Z + +[Term] +id: GO:2000482 +name: regulation of interleukin-8 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-8 secretion." [GOC:obol] +synonym: "regulation of IL-8 secretion" EXACT [GOC:obol] +is_a: GO:0032677 ! regulation of interleukin-8 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072606 ! interleukin-8 secretion +relationship: regulates GO:0072606 ! interleukin-8 secretion +created_by: yaf +creation_date: 2011-03-10T02:37:11Z + +[Term] +id: GO:2000483 +name: negative regulation of interleukin-8 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-8 secretion." [GOC:obol] +synonym: "negative regulation of IL-8 secretion" EXACT [GOC:obol] +is_a: GO:0032717 ! negative regulation of interleukin-8 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2000482 ! regulation of interleukin-8 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072606 ! interleukin-8 secretion +relationship: negatively_regulates GO:0072606 ! interleukin-8 secretion +created_by: yaf +creation_date: 2011-03-10T02:37:51Z + +[Term] +id: GO:2000484 +name: positive regulation of interleukin-8 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion." [GOC:obol] +synonym: "positive regulation of IL-8 secretion" EXACT [GOC:obol] +is_a: GO:0032757 ! positive regulation of interleukin-8 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2000482 ! regulation of interleukin-8 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072606 ! interleukin-8 secretion +relationship: positively_regulates GO:0072606 ! interleukin-8 secretion +created_by: yaf +creation_date: 2011-03-10T02:38:20Z + +[Term] +id: GO:2000485 +name: regulation of glutamine transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glutamine transport." [GOC:obol] +synonym: "regulation of L-glutamine transport" RELATED [GOC:obol] +is_a: GO:0051955 ! regulation of amino acid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006868 ! glutamine transport +relationship: regulates GO:0006868 ! glutamine transport +created_by: bf +creation_date: 2011-03-11T09:32:23Z + +[Term] +id: GO:2000486 +name: negative regulation of glutamine transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport." [GOC:obol] +synonym: "negative regulation of L-glutamine transport" RELATED [GOC:obol] +is_a: GO:0051956 ! negative regulation of amino acid transport +is_a: GO:2000485 ! regulation of glutamine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006868 ! glutamine transport +relationship: negatively_regulates GO:0006868 ! glutamine transport +created_by: bf +creation_date: 2011-03-11T09:33:07Z + +[Term] +id: GO:2000487 +name: positive regulation of glutamine transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glutamine transport." [GOC:obol] +synonym: "positive regulation of L-glutamine transport" RELATED [GOC:obol] +is_a: GO:0051957 ! positive regulation of amino acid transport +is_a: GO:2000485 ! regulation of glutamine transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006868 ! glutamine transport +relationship: positively_regulates GO:0006868 ! glutamine transport +created_by: bf +creation_date: 2011-03-11T09:33:39Z + +[Term] +id: GO:2000488 +name: positive regulation of brassinosteroid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process." [GOC:obol] +synonym: "positive regulation of brassinosteroid anabolism" EXACT [GOC:obol] +synonym: "positive regulation of brassinosteroid biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of brassinosteroid formation" EXACT [GOC:obol] +synonym: "positive regulation of brassinosteroid synthesis" EXACT [GOC:obol] +is_a: GO:0010422 ! regulation of brassinosteroid biosynthetic process +is_a: GO:0010893 ! positive regulation of steroid biosynthetic process +is_a: GO:0046886 ! positive regulation of hormone biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0016132 ! brassinosteroid biosynthetic process +relationship: positively_regulates GO:0016132 ! brassinosteroid biosynthetic process +created_by: dhl +creation_date: 2011-03-11T06:48:45Z + +[Term] +id: GO:2000489 +name: regulation of hepatic stellate cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hepatic stellate cell activation." [GOC:obol] +is_a: GO:0050865 ! regulation of cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035733 ! hepatic stellate cell activation +relationship: regulates GO:0035733 ! hepatic stellate cell activation +created_by: bf +creation_date: 2011-03-14T03:48:32Z + +[Term] +id: GO:2000490 +name: negative regulation of hepatic stellate cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation." [GOC:obol] +is_a: GO:0050866 ! negative regulation of cell activation +is_a: GO:2000489 ! regulation of hepatic stellate cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035733 ! hepatic stellate cell activation +relationship: negatively_regulates GO:0035733 ! hepatic stellate cell activation +created_by: bf +creation_date: 2011-03-14T03:49:18Z + +[Term] +id: GO:2000491 +name: positive regulation of hepatic stellate cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation." [GOC:obol] +is_a: GO:0050867 ! positive regulation of cell activation +is_a: GO:2000489 ! regulation of hepatic stellate cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035733 ! hepatic stellate cell activation +relationship: positively_regulates GO:0035733 ! hepatic stellate cell activation +created_by: bf +creation_date: 2011-03-14T03:49:48Z + +[Term] +id: GO:2000492 +name: regulation of interleukin-18-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway." [GOC:obol] +synonym: "regulation of interleukin-18-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035655 ! interleukin-18-mediated signaling pathway +relationship: regulates GO:0035655 ! interleukin-18-mediated signaling pathway +created_by: pr +creation_date: 2011-03-16T01:59:18Z + +[Term] +id: GO:2000493 +name: negative regulation of interleukin-18-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway." [GOC:obol] +synonym: "negative regulation of interleukin-18-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:2000492 ! regulation of interleukin-18-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035655 ! interleukin-18-mediated signaling pathway +relationship: negatively_regulates GO:0035655 ! interleukin-18-mediated signaling pathway +created_by: pr +creation_date: 2011-03-16T02:00:12Z + +[Term] +id: GO:2000494 +name: positive regulation of interleukin-18-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway." [GOC:obol] +synonym: "positive regulation of interleukin-18-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:2000492 ! regulation of interleukin-18-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035655 ! interleukin-18-mediated signaling pathway +relationship: positively_regulates GO:0035655 ! interleukin-18-mediated signaling pathway +created_by: pr +creation_date: 2011-03-16T02:00:50Z + +[Term] +id: GO:2000495 +name: regulation of cell proliferation involved in compound eye morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] +is_a: GO:0042127 ! regulation of cell population proliferation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +relationship: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +created_by: bf +creation_date: 2011-03-18T02:18:34Z + +[Term] +id: GO:2000496 +name: negative regulation of cell proliferation involved in compound eye morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +relationship: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +created_by: bf +creation_date: 2011-03-18T02:19:22Z + +[Term] +id: GO:2000497 +name: positive regulation of cell proliferation involved in compound eye morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +relationship: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis +created_by: bf +creation_date: 2011-03-18T02:19:54Z + +[Term] +id: GO:2000498 +name: obsolete regulation of induction of apoptosis in response to chemical stimulus +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of induction of apoptosis in response to chemical stimulus." [GOC:mtg_apoptosis, GOC:obol] +comment: This term was made obsolete because it is ill-defined. +synonym: "regulation of induction of apoptosis in response to chemical stimulus" EXACT [] +synonym: "regulation of induction of apoptosis in response to chemical substance" EXACT [GOC:obol] +is_obsolete: true +created_by: yaf +creation_date: 2011-03-18T02:34:53Z + +[Term] +id: GO:2000499 +name: obsolete negative regulation of induction of apoptosis in response to chemical stimulus +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of induction of apoptosis in response to chemical stimulus." [GOC:mtg_apoptosis, GOC:obol] +comment: This term was made obsolete because it is ill-defined. +synonym: "negative regulation of induction of apoptosis in response to chemical stimulus" EXACT [] +synonym: "negative regulation of induction of apoptosis in response to chemical substance" EXACT [GOC:obol] +is_obsolete: true +created_by: yaf +creation_date: 2011-03-18T02:35:44Z + +[Term] +id: GO:2000500 +name: obsolete positive regulation of induction of apoptosis in response to chemical stimulus +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of induction of apoptosis in response to chemical stimulus." [GOC:mtg_apoptosis, GOC:obol] +comment: This term was made obsolete because it is ill-defined. +synonym: "positive regulation of induction of apoptosis in response to chemical stimulus" EXACT [] +synonym: "positive regulation of induction of apoptosis in response to chemical substance" EXACT [GOC:obol] +is_obsolete: true +created_by: yaf +creation_date: 2011-03-18T02:36:22Z + +[Term] +id: GO:2000501 +name: regulation of natural killer cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis." [GOC:BHF] +is_a: GO:1901623 ! regulation of lymphocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035747 ! natural killer cell chemotaxis +relationship: regulates GO:0035747 ! natural killer cell chemotaxis +created_by: bf +creation_date: 2011-03-21T10:09:23Z + +[Term] +id: GO:2000502 +name: negative regulation of natural killer cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis." [GOC:BHF] +is_a: GO:1901624 ! negative regulation of lymphocyte chemotaxis +is_a: GO:2000501 ! regulation of natural killer cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035747 ! natural killer cell chemotaxis +relationship: negatively_regulates GO:0035747 ! natural killer cell chemotaxis +created_by: bf +creation_date: 2011-03-21T10:09:32Z + +[Term] +id: GO:2000503 +name: positive regulation of natural killer cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis." [GOC:BHF] +is_a: GO:0140131 ! positive regulation of lymphocyte chemotaxis +is_a: GO:2000501 ! regulation of natural killer cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035747 ! natural killer cell chemotaxis +relationship: positively_regulates GO:0035747 ! natural killer cell chemotaxis +created_by: bf +creation_date: 2011-03-21T10:09:38Z + +[Term] +id: GO:2000504 +name: positive regulation of blood vessel remodeling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of blood vessel remodeling." [GOC:obol] +is_a: GO:0034105 ! positive regulation of tissue remodeling +is_a: GO:0060312 ! regulation of blood vessel remodeling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001974 ! blood vessel remodeling +relationship: positively_regulates GO:0001974 ! blood vessel remodeling +created_by: pr +creation_date: 2011-03-21T10:33:20Z + +[Term] +id: GO:2000508 +name: regulation of dendritic cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis." [GOC:obol] +is_a: GO:0002688 ! regulation of leukocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002407 ! dendritic cell chemotaxis +relationship: regulates GO:0002407 ! dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-22T10:21:38Z + +[Term] +id: GO:2000509 +name: negative regulation of dendritic cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis." [GOC:obol] +is_a: GO:0002689 ! negative regulation of leukocyte chemotaxis +is_a: GO:2000508 ! regulation of dendritic cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002407 ! dendritic cell chemotaxis +relationship: negatively_regulates GO:0002407 ! dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-22T10:21:45Z + +[Term] +id: GO:2000510 +name: positive regulation of dendritic cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis." [GOC:obol] +is_a: GO:0002690 ! positive regulation of leukocyte chemotaxis +is_a: GO:2000508 ! regulation of dendritic cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002407 ! dendritic cell chemotaxis +relationship: positively_regulates GO:0002407 ! dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-22T10:21:49Z + +[Term] +id: GO:2000511 +name: regulation of granzyme A production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of granzyme A production." [GOC:obol] +is_a: GO:0002700 ! regulation of production of molecular mediator of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035746 ! granzyme A production +relationship: regulates GO:0035746 ! granzyme A production +created_by: ebc +creation_date: 2011-03-22T10:31:27Z + +[Term] +id: GO:2000512 +name: negative regulation of granzyme A production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production." [GOC:obol] +is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response +is_a: GO:2000511 ! regulation of granzyme A production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035746 ! granzyme A production +relationship: negatively_regulates GO:0035746 ! granzyme A production +created_by: ebc +creation_date: 2011-03-22T10:31:32Z + +[Term] +id: GO:2000513 +name: positive regulation of granzyme A production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of granzyme A production." [GOC:obol] +is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response +is_a: GO:2000511 ! regulation of granzyme A production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035746 ! granzyme A production +relationship: positively_regulates GO:0035746 ! granzyme A production +created_by: ebc +creation_date: 2011-03-22T10:31:36Z + +[Term] +id: GO:2000514 +name: regulation of CD4-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +relationship: regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +created_by: ebc +creation_date: 2011-03-22T10:36:56Z + +[Term] +id: GO:2000515 +name: negative regulation of CD4-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046636 ! negative regulation of alpha-beta T cell activation +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +relationship: negatively_regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +created_by: ebc +creation_date: 2011-03-22T10:37:02Z + +[Term] +id: GO:2000516 +name: positive regulation of CD4-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046635 ! positive regulation of alpha-beta T cell activation +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +relationship: positively_regulates GO:0035710 ! CD4-positive, alpha-beta T cell activation +created_by: ebc +creation_date: 2011-03-22T10:37:06Z + +[Term] +id: GO:2000517 +name: regulation of T-helper 1 cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 1 cell activation." [GOC:obol] +synonym: "regulation of Th1 cell activation" EXACT [GOC:obol] +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035711 ! T-helper 1 cell activation +relationship: regulates GO:0035711 ! T-helper 1 cell activation +created_by: ebc +creation_date: 2011-03-22T10:40:19Z + +[Term] +id: GO:2000518 +name: negative regulation of T-helper 1 cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation." [GOC:obol] +synonym: "negative regulation of Th1 cell activation" EXACT [GOC:obol] +is_a: GO:2000515 ! negative regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000517 ! regulation of T-helper 1 cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035711 ! T-helper 1 cell activation +relationship: negatively_regulates GO:0035711 ! T-helper 1 cell activation +created_by: ebc +creation_date: 2011-03-22T10:40:26Z + +[Term] +id: GO:2000519 +name: positive regulation of T-helper 1 cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation." [GOC:obol] +synonym: "positive regulation of Th1 cell activation" EXACT [GOC:obol] +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000517 ! regulation of T-helper 1 cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035711 ! T-helper 1 cell activation +relationship: positively_regulates GO:0035711 ! T-helper 1 cell activation +created_by: ebc +creation_date: 2011-03-22T10:40:31Z + +[Term] +id: GO:2000520 +name: regulation of immunological synapse formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of immunological synapse formation." [GOC:obol] +synonym: "regulation of formation of immunological synapse" EXACT [GOC:obol] +is_a: GO:0051249 ! regulation of lymphocyte activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001771 ! immunological synapse formation +relationship: regulates GO:0001771 ! immunological synapse formation +created_by: ebc +creation_date: 2011-03-23T10:18:14Z + +[Term] +id: GO:2000521 +name: negative regulation of immunological synapse formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation." [GOC:obol] +synonym: "negative regulation of formation of immunological synapse" EXACT [GOC:obol] +is_a: GO:0051250 ! negative regulation of lymphocyte activation +is_a: GO:2000520 ! regulation of immunological synapse formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001771 ! immunological synapse formation +relationship: negatively_regulates GO:0001771 ! immunological synapse formation +created_by: ebc +creation_date: 2011-03-23T10:18:19Z + +[Term] +id: GO:2000522 +name: positive regulation of immunological synapse formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of immunological synapse formation." [GOC:obol] +synonym: "positive regulation of formation of immunological synapse" EXACT [GOC:obol] +is_a: GO:0051251 ! positive regulation of lymphocyte activation +is_a: GO:2000520 ! regulation of immunological synapse formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001771 ! immunological synapse formation +relationship: positively_regulates GO:0001771 ! immunological synapse formation +created_by: ebc +creation_date: 2011-03-23T10:18:23Z + +[Term] +id: GO:2000523 +name: regulation of T cell costimulation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell costimulation." [GOC:obol] +synonym: "regulation of T cell co-stimulation" EXACT [GOC:obol] +synonym: "regulation of T lymphocyte costimulation" EXACT [GOC:obol] +synonym: "regulation of T-cell co-stimulation" EXACT [GOC:obol] +synonym: "regulation of T-cell costimulation" EXACT [GOC:obol] +synonym: "regulation of T-lymphocyte costimulation" EXACT [GOC:obol] +is_a: GO:0050863 ! regulation of T cell activation +is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031295 ! T cell costimulation +relationship: regulates GO:0031295 ! T cell costimulation +created_by: ebc +creation_date: 2011-03-23T10:23:24Z + +[Term] +id: GO:2000524 +name: negative regulation of T cell costimulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation." [GOC:obol] +synonym: "negative regulation of T cell co-stimulation" EXACT [GOC:obol] +synonym: "negative regulation of T lymphocyte costimulation" EXACT [GOC:obol] +synonym: "negative regulation of T-cell co-stimulation" EXACT [GOC:obol] +synonym: "negative regulation of T-cell costimulation" EXACT [GOC:obol] +synonym: "negative regulation of T-lymphocyte costimulation" EXACT [GOC:obol] +is_a: GO:0002683 ! negative regulation of immune system process +is_a: GO:2000523 ! regulation of T cell costimulation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031295 ! T cell costimulation +relationship: negatively_regulates GO:0031295 ! T cell costimulation +created_by: ebc +creation_date: 2011-03-23T10:23:31Z + +[Term] +id: GO:2000525 +name: positive regulation of T cell costimulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell costimulation." [GOC:obol] +synonym: "positive regulation of T cell co-stimulation" EXACT [GOC:obol] +synonym: "positive regulation of T lymphocyte costimulation" EXACT [GOC:obol] +synonym: "positive regulation of T-cell co-stimulation" EXACT [GOC:obol] +synonym: "positive regulation of T-cell costimulation" EXACT [GOC:obol] +synonym: "positive regulation of T-lymphocyte costimulation" EXACT [GOC:obol] +is_a: GO:0050870 ! positive regulation of T cell activation +is_a: GO:2000523 ! regulation of T cell costimulation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031295 ! T cell costimulation +relationship: positively_regulates GO:0031295 ! T cell costimulation +created_by: ebc +creation_date: 2011-03-23T10:23:36Z + +[Term] +id: GO:2000526 +name: positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation +namespace: biological_process +def: "Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation." [GOC:obol] +synonym: "positive regulation of glycoprotein biosynthetic process of formation of immunological synapse" EXACT [GOC:obol] +synonym: "positive regulation of glycoprotein biosynthetic process of immunological synapse formation" EXACT [GOC:obol] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +intersection_of: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +intersection_of: part_of GO:0001771 ! immunological synapse formation +relationship: part_of GO:0001771 ! immunological synapse formation +created_by: ebc +creation_date: 2011-03-23T10:42:30Z + +[Term] +id: GO:2000527 +name: regulation of myeloid dendritic cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis." [GOC:obol] +is_a: GO:2000508 ! regulation of dendritic cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002408 ! myeloid dendritic cell chemotaxis +relationship: regulates GO:0002408 ! myeloid dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-23T12:18:32Z + +[Term] +id: GO:2000528 +name: negative regulation of myeloid dendritic cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis." [GOC:obol] +is_a: GO:2000509 ! negative regulation of dendritic cell chemotaxis +is_a: GO:2000527 ! regulation of myeloid dendritic cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002408 ! myeloid dendritic cell chemotaxis +relationship: negatively_regulates GO:0002408 ! myeloid dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-23T12:18:39Z + +[Term] +id: GO:2000529 +name: positive regulation of myeloid dendritic cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis." [GOC:obol] +is_a: GO:2000510 ! positive regulation of dendritic cell chemotaxis +is_a: GO:2000527 ! regulation of myeloid dendritic cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002408 ! myeloid dendritic cell chemotaxis +relationship: positively_regulates GO:0002408 ! myeloid dendritic cell chemotaxis +created_by: ebc +creation_date: 2011-03-23T12:18:45Z + +[Term] +id: GO:2000530 +name: obsolete positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of insulin secretion involved in cellular response to glucose stimulus." [GOC:obol] +synonym: "positive regulation of regulation of insulin secretion in response to glucose" EXACT [GOC:obol] +synonym: "positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus" EXACT [] +is_obsolete: true +created_by: yaf +creation_date: 2011-03-24T09:27:37Z + +[Term] +id: GO:2000531 +name: obsolete regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:vw] +comment: This term was obsoleted because it represents a GO-CAM model. +is_obsolete: true +created_by: dph +creation_date: 2011-03-24T12:18:33Z + +[Term] +id: GO:2000532 +name: regulation of renal albumin absorption +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of renal albumin absorption." [GOC:obol, GOC:yaf] +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097018 ! renal albumin absorption +relationship: regulates GO:0097018 ! renal albumin absorption +created_by: pr +creation_date: 2011-03-24T03:28:06Z + +[Term] +id: GO:2000533 +name: negative regulation of renal albumin absorption +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption." [GOC:obol, GOC:yaf] +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000532 ! regulation of renal albumin absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097018 ! renal albumin absorption +relationship: negatively_regulates GO:0097018 ! renal albumin absorption +created_by: pr +creation_date: 2011-03-24T03:28:11Z + +[Term] +id: GO:2000534 +name: positive regulation of renal albumin absorption +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of renal albumin absorption." [GOC:obol, GOC:yaf] +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000532 ! regulation of renal albumin absorption +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097018 ! renal albumin absorption +relationship: positively_regulates GO:0097018 ! renal albumin absorption +created_by: pr +creation_date: 2011-03-24T03:28:14Z + +[Term] +id: GO:2000535 +name: regulation of entry of bacterium into host cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of entry of bacterium into host cell." [GOC:obol] +synonym: "regulation of bacterial entry into host cell" EXACT [GOC:obol] +synonym: "regulation of invasion of bacteria into host cell" EXACT [GOC:obol] +is_a: GO:0052372 ! modulation by symbiont of entry into host +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035635 ! entry of bacterium into host cell +relationship: regulates GO:0035635 ! entry of bacterium into host cell +created_by: ebc +creation_date: 2011-03-28T09:52:16Z + +[Term] +id: GO:2000536 +name: negative regulation of entry of bacterium into host cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell." [GOC:obol] +synonym: "negative regulation of bacterial entry into host cell" EXACT [GOC:obol] +synonym: "negative regulation of invasion of bacteria into host cell" EXACT [GOC:obol] +is_a: GO:0048519 ! negative regulation of biological process +is_a: GO:2000535 ! regulation of entry of bacterium into host cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035635 ! entry of bacterium into host cell +relationship: negatively_regulates GO:0035635 ! entry of bacterium into host cell +created_by: ebc +creation_date: 2011-03-28T09:52:23Z + +[Term] +id: GO:2000537 +name: regulation of B cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of B cell chemotaxis." [GOC:obol] +is_a: GO:1901623 ! regulation of lymphocyte chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035754 ! B cell chemotaxis +relationship: regulates GO:0035754 ! B cell chemotaxis +created_by: ebc +creation_date: 2011-03-29T09:49:25Z + +[Term] +id: GO:2000538 +name: positive regulation of B cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of B cell chemotaxis." [GOC:obol] +is_a: GO:0140131 ! positive regulation of lymphocyte chemotaxis +is_a: GO:2000537 ! regulation of B cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035754 ! B cell chemotaxis +relationship: positively_regulates GO:0035754 ! B cell chemotaxis +created_by: ebc +creation_date: 2011-03-29T09:49:33Z + +[Term] +id: GO:2000539 +name: regulation of protein geranylgeranylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] +synonym: "regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] +synonym: "regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] +is_a: GO:0031399 ! regulation of protein modification process +is_a: GO:2000112 ! regulation of cellular macromolecule biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018344 ! protein geranylgeranylation +relationship: regulates GO:0018344 ! protein geranylgeranylation +created_by: tb +creation_date: 2011-03-29T06:23:05Z + +[Term] +id: GO:2000540 +name: negative regulation of protein geranylgeranylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] +synonym: "negative regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] +synonym: "negative regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] +is_a: GO:0031400 ! negative regulation of protein modification process +is_a: GO:2000539 ! regulation of protein geranylgeranylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018344 ! protein geranylgeranylation +relationship: negatively_regulates GO:0018344 ! protein geranylgeranylation +created_by: tb +creation_date: 2011-03-29T06:23:11Z + +[Term] +id: GO:2000541 +name: positive regulation of protein geranylgeranylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] +synonym: "positive regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] +synonym: "positive regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] +is_a: GO:0031401 ! positive regulation of protein modification process +is_a: GO:2000539 ! regulation of protein geranylgeranylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018344 ! protein geranylgeranylation +relationship: positively_regulates GO:0018344 ! protein geranylgeranylation +created_by: tb +creation_date: 2011-03-29T06:23:15Z + +[Term] +id: GO:2000542 +name: negative regulation of gastrulation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0045992 ! negative regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007369 ! gastrulation +relationship: negatively_regulates GO:0007369 ! gastrulation +created_by: yaf +creation_date: 2011-04-01T04:10:08Z + +[Term] +id: GO:2000543 +name: positive regulation of gastrulation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol] +is_a: GO:0010470 ! regulation of gastrulation +is_a: GO:0040019 ! positive regulation of embryonic development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007369 ! gastrulation +relationship: positively_regulates GO:0007369 ! gastrulation +created_by: yaf +creation_date: 2011-04-01T04:10:15Z + +[Term] +id: GO:2000544 +name: regulation of endothelial cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor." [GOC:obol] +is_a: GO:1904847 ! regulation of cell chemotaxis to fibroblast growth factor +is_a: GO:2001026 ! regulation of endothelial cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +relationship: regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +created_by: ebc +creation_date: 2011-04-03T07:14:04Z + +[Term] +id: GO:2000545 +name: negative regulation of endothelial cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor." [GOC:obol] +is_a: GO:1904848 ! negative regulation of cell chemotaxis to fibroblast growth factor +is_a: GO:2000544 ! regulation of endothelial cell chemotaxis to fibroblast growth factor +is_a: GO:2001027 ! negative regulation of endothelial cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +relationship: negatively_regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +created_by: ebc +creation_date: 2011-04-03T07:14:11Z + +[Term] +id: GO:2000546 +name: positive regulation of endothelial cell chemotaxis to fibroblast growth factor +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor." [GOC:obol] +is_a: GO:1904849 ! positive regulation of cell chemotaxis to fibroblast growth factor +is_a: GO:2000544 ! regulation of endothelial cell chemotaxis to fibroblast growth factor +is_a: GO:2001028 ! positive regulation of endothelial cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +relationship: positively_regulates GO:0035768 ! endothelial cell chemotaxis to fibroblast growth factor +created_by: ebc +creation_date: 2011-04-03T07:17:27Z + +[Term] +id: GO:2000547 +name: regulation of dendritic cell dendrite assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] +synonym: "regulation of dendritic extension" RELATED [GOC:obol] +is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097026 ! dendritic cell dendrite assembly +relationship: regulates GO:0097026 ! dendritic cell dendrite assembly +created_by: ebc +creation_date: 2011-04-03T07:21:55Z + +[Term] +id: GO:2000548 +name: negative regulation of dendritic cell dendrite assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] +synonym: "negative regulation of dendritic extension" RELATED [GOC:obol] +is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly +is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly +relationship: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly +created_by: ebc +creation_date: 2011-04-03T07:22:01Z + +[Term] +id: GO:2000549 +name: positive regulation of dendritic cell dendrite assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] +synonym: "positive regulation of dendritic extension" RELATED [GOC:obol] +is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly +is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097026 ! dendritic cell dendrite assembly +relationship: positively_regulates GO:0097026 ! dendritic cell dendrite assembly +created_by: ebc +creation_date: 2011-04-03T07:22:06Z + +[Term] +id: GO:2000550 +name: negative regulation of B cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis." [GOC:obol] +is_a: GO:1901624 ! negative regulation of lymphocyte chemotaxis +is_a: GO:2000537 ! regulation of B cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035754 ! B cell chemotaxis +relationship: negatively_regulates GO:0035754 ! B cell chemotaxis +created_by: ebc +creation_date: 2011-04-03T07:25:59Z + +[Term] +id: GO:2000551 +name: regulation of T-helper 2 cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production." [GOC:obol] +synonym: "regulation of Th2 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002724 ! regulation of T cell cytokine production +is_a: GO:0002828 ! regulation of type 2 immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035745 ! T-helper 2 cell cytokine production +relationship: regulates GO:0035745 ! T-helper 2 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:32:47Z + +[Term] +id: GO:2000552 +name: negative regulation of T-helper 2 cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production." [GOC:obol] +synonym: "negative regulation of Th2 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002725 ! negative regulation of T cell cytokine production +is_a: GO:0002829 ! negative regulation of type 2 immune response +is_a: GO:2000551 ! regulation of T-helper 2 cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035745 ! T-helper 2 cell cytokine production +relationship: negatively_regulates GO:0035745 ! T-helper 2 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:32:54Z + +[Term] +id: GO:2000553 +name: positive regulation of T-helper 2 cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production." [GOC:obol] +synonym: "positive regulation of Th2 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002726 ! positive regulation of T cell cytokine production +is_a: GO:0002830 ! positive regulation of type 2 immune response +is_a: GO:2000551 ! regulation of T-helper 2 cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035745 ! T-helper 2 cell cytokine production +relationship: positively_regulates GO:0035745 ! T-helper 2 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:32:58Z + +[Term] +id: GO:2000554 +name: regulation of T-helper 1 cell cytokine production +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production." [GOC:obol] +synonym: "regulation of Th1 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002724 ! regulation of T cell cytokine production +is_a: GO:0002825 ! regulation of T-helper 1 type immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035744 ! T-helper 1 cell cytokine production +relationship: regulates GO:0035744 ! T-helper 1 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:35:43Z + +[Term] +id: GO:2000555 +name: negative regulation of T-helper 1 cell cytokine production +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production." [GOC:obol] +synonym: "negative regulation of Th1 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002725 ! negative regulation of T cell cytokine production +is_a: GO:0002826 ! negative regulation of T-helper 1 type immune response +is_a: GO:2000554 ! regulation of T-helper 1 cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035744 ! T-helper 1 cell cytokine production +relationship: negatively_regulates GO:0035744 ! T-helper 1 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:35:51Z + +[Term] +id: GO:2000556 +name: positive regulation of T-helper 1 cell cytokine production +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production." [GOC:obol] +synonym: "positive regulation of Th1 cell cytokine production" EXACT [GOC:obol] +is_a: GO:0002726 ! positive regulation of T cell cytokine production +is_a: GO:0002827 ! positive regulation of T-helper 1 type immune response +is_a: GO:2000554 ! regulation of T-helper 1 cell cytokine production +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035744 ! T-helper 1 cell cytokine production +relationship: positively_regulates GO:0035744 ! T-helper 1 cell cytokine production +created_by: ebc +creation_date: 2011-04-03T07:35:56Z + +[Term] +id: GO:2000557 +name: regulation of immunoglobulin production in mucosal tissue +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue." [GOC:obol] +synonym: "regulation of antibody production in mucosal tissue" EXACT [GOC:obol] +is_a: GO:0002637 ! regulation of immunoglobulin production +is_a: GO:0002889 ! regulation of immunoglobulin mediated immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002426 ! immunoglobulin production in mucosal tissue +relationship: regulates GO:0002426 ! immunoglobulin production in mucosal tissue +created_by: ebc +creation_date: 2011-04-03T07:52:09Z + +[Term] +id: GO:2000558 +name: positive regulation of immunoglobulin production in mucosal tissue +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue." [GOC:obol] +synonym: "positive regulation of antibody production in mucosal tissue" EXACT [GOC:obol] +is_a: GO:0002639 ! positive regulation of immunoglobulin production +is_a: GO:0002891 ! positive regulation of immunoglobulin mediated immune response +is_a: GO:2000557 ! regulation of immunoglobulin production in mucosal tissue +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002426 ! immunoglobulin production in mucosal tissue +relationship: positively_regulates GO:0002426 ! immunoglobulin production in mucosal tissue +created_by: ebc +creation_date: 2011-04-03T07:52:17Z + +[Term] +id: GO:2000559 +name: regulation of CD24 biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD24 biosynthetic process." [GOC:obol] +synonym: "regulation of CD24 anabolism" EXACT [GOC:obol] +synonym: "regulation of CD24 biosynthesis" EXACT [GOC:obol] +synonym: "regulation of CD24 formation" EXACT [GOC:obol] +synonym: "regulation of CD24 synthesis" EXACT [GOC:obol] +is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035724 ! CD24 biosynthetic process +relationship: regulates GO:0035724 ! CD24 biosynthetic process +created_by: ebc +creation_date: 2011-04-03T08:56:56Z + +[Term] +id: GO:2000560 +name: positive regulation of CD24 biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process." [GOC:obol] +synonym: "positive regulation of CD24 anabolism" EXACT [GOC:obol] +synonym: "positive regulation of CD24 biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of CD24 formation" EXACT [GOC:obol] +synonym: "positive regulation of CD24 synthesis" EXACT [GOC:obol] +is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process +is_a: GO:2000559 ! regulation of CD24 biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035724 ! CD24 biosynthetic process +relationship: positively_regulates GO:0035724 ! CD24 biosynthetic process +created_by: ebc +creation_date: 2011-04-03T08:57:02Z + +[Term] +id: GO:2000561 +name: regulation of CD4-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046640 ! regulation of alpha-beta T cell proliferation +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +relationship: regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:01:04Z + +[Term] +id: GO:2000562 +name: negative regulation of CD4-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046642 ! negative regulation of alpha-beta T cell proliferation +is_a: GO:2000515 ! negative regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000561 ! regulation of CD4-positive, alpha-beta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +relationship: negatively_regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:01:11Z + +[Term] +id: GO:2000563 +name: positive regulation of CD4-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046641 ! positive regulation of alpha-beta T cell proliferation +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000561 ! regulation of CD4-positive, alpha-beta T cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +relationship: positively_regulates GO:0035739 ! CD4-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:01:15Z + +[Term] +id: GO:2000564 +name: regulation of CD8-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046640 ! regulation of alpha-beta T cell proliferation +is_a: GO:2001185 ! regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +relationship: regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:03:13Z + +[Term] +id: GO:2000565 +name: negative regulation of CD8-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046642 ! negative regulation of alpha-beta T cell proliferation +is_a: GO:2000564 ! regulation of CD8-positive, alpha-beta T cell proliferation +is_a: GO:2001186 ! negative regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +relationship: negatively_regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:03:19Z + +[Term] +id: GO:2000566 +name: positive regulation of CD8-positive, alpha-beta T cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation." [GOC:obol] +is_a: GO:0046641 ! positive regulation of alpha-beta T cell proliferation +is_a: GO:2000564 ! regulation of CD8-positive, alpha-beta T cell proliferation +is_a: GO:2001187 ! positive regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +relationship: positively_regulates GO:0035740 ! CD8-positive, alpha-beta T cell proliferation +created_by: ebc +creation_date: 2011-04-03T09:03:24Z + +[Term] +id: GO:2000567 +name: regulation of memory T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of memory T cell activation." [GOC:obol] +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035709 ! memory T cell activation +relationship: regulates GO:0035709 ! memory T cell activation +created_by: ebc +creation_date: 2011-04-03T09:10:06Z + +[Term] +id: GO:2000568 +name: positive regulation of memory T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of memory T cell activation." [GOC:obol] +is_a: GO:0050870 ! positive regulation of T cell activation +is_a: GO:2000567 ! regulation of memory T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035709 ! memory T cell activation +relationship: positively_regulates GO:0035709 ! memory T cell activation +created_by: ebc +creation_date: 2011-04-03T09:10:12Z + +[Term] +id: GO:2000569 +name: regulation of T-helper 2 cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T-helper 2 cell activation." [GOC:obol] +synonym: "regulation of Th2 cell activation" EXACT [GOC:obol] +is_a: GO:2000514 ! regulation of CD4-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035712 ! T-helper 2 cell activation +relationship: regulates GO:0035712 ! T-helper 2 cell activation +created_by: ebc +creation_date: 2011-04-03T09:14:53Z + +[Term] +id: GO:2000570 +name: positive regulation of T-helper 2 cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation." [GOC:obol] +synonym: "positive regulation of Th2 cell activation" EXACT [GOC:obol] +is_a: GO:2000516 ! positive regulation of CD4-positive, alpha-beta T cell activation +is_a: GO:2000569 ! regulation of T-helper 2 cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035712 ! T-helper 2 cell activation +relationship: positively_regulates GO:0035712 ! T-helper 2 cell activation +created_by: ebc +creation_date: 2011-04-03T09:14:59Z + +[Term] +id: GO:2000571 +name: regulation of interleukin-4-dependent isotype switching to IgE isotypes +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes." [GOC:obol] +synonym: "regulation of IL-4-dependent isotype switching to IgE isotypes" EXACT [GOC:obol] +is_a: GO:0048293 ! regulation of isotype switching to IgE isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035708 ! interleukin-4-dependent isotype switching to IgE isotypes +relationship: regulates GO:0035708 ! interleukin-4-dependent isotype switching to IgE isotypes +created_by: ebc +creation_date: 2011-04-03T09:20:11Z + +[Term] +id: GO:2000572 +name: positive regulation of interleukin-4-dependent isotype switching to IgE isotypes +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes." [GOC:obol] +synonym: "positive regulation of IL-4-dependent isotype switching to IgE isotypes" EXACT [GOC:obol] +is_a: GO:0048295 ! positive regulation of isotype switching to IgE isotypes +is_a: GO:2000571 ! regulation of interleukin-4-dependent isotype switching to IgE isotypes +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035708 ! interleukin-4-dependent isotype switching to IgE isotypes +relationship: positively_regulates GO:0035708 ! interleukin-4-dependent isotype switching to IgE isotypes +created_by: ebc +creation_date: 2011-04-03T09:20:18Z + +[Term] +id: GO:2000573 +name: positive regulation of DNA biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] +synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol] +synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of DNA formation" EXACT [GOC:obol] +synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:0051054 ! positive regulation of DNA metabolic process +is_a: GO:2000278 ! regulation of DNA biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071897 ! DNA biosynthetic process +relationship: positively_regulates GO:0071897 ! DNA biosynthetic process +created_by: yaf +creation_date: 2011-04-04T10:01:20Z + +[Term] +id: GO:2000574 +name: regulation of microtubule motor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of microtubule motor activity." [GOC:kmv] +synonym: "regulation of axonemal motor activity" RELATED [GOC:obol] +synonym: "regulation of dynein" RELATED [GOC:obol] +synonym: "regulation of dynein ATPase activity" RELATED [GOC:obol] +synonym: "regulation of kinesin" RELATED [GOC:obol] +synonym: "regulation of kinesin motor activity" RELATED [GOC:obol] +synonym: "regulation of kinetochore motor activity" RELATED [GOC:obol] +is_a: GO:0051336 ! regulation of hydrolase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003777 ! microtubule motor activity +relationship: regulates GO:0003777 ! microtubule motor activity +created_by: bf +creation_date: 2011-04-05T08:36:44Z + +[Term] +id: GO:2000575 +name: negative regulation of microtubule motor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity." [GOC:kmv] +synonym: "negative regulation of axonemal motor activity" RELATED [GOC:obol] +synonym: "negative regulation of dynein" RELATED [GOC:obol] +synonym: "negative regulation of dynein ATPase activity" RELATED [GOC:obol] +synonym: "negative regulation of kinesin" RELATED [GOC:obol] +synonym: "negative regulation of kinesin motor activity" RELATED [GOC:obol] +synonym: "negative regulation of kinetochore motor activity" RELATED [GOC:obol] +is_a: GO:0051346 ! negative regulation of hydrolase activity +is_a: GO:2000574 ! regulation of microtubule motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003777 ! microtubule motor activity +relationship: negatively_regulates GO:0003777 ! microtubule motor activity +created_by: bf +creation_date: 2011-04-05T08:36:48Z + +[Term] +id: GO:2000576 +name: positive regulation of microtubule motor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of microtubule motor activity." [GOC:kmv] +synonym: "positive regulation of axonemal motor activity" RELATED [GOC:obol] +synonym: "positive regulation of dynein" RELATED [GOC:obol] +synonym: "positive regulation of dynein ATPase activity" RELATED [GOC:obol] +synonym: "positive regulation of kinesin" RELATED [GOC:obol] +synonym: "positive regulation of kinesin motor activity" RELATED [GOC:obol] +synonym: "positive regulation of kinetochore motor activity" RELATED [GOC:obol] +is_a: GO:0051345 ! positive regulation of hydrolase activity +is_a: GO:2000574 ! regulation of microtubule motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003777 ! microtubule motor activity +relationship: positively_regulates GO:0003777 ! microtubule motor activity +created_by: bf +creation_date: 2011-04-05T08:36:51Z + +[Term] +id: GO:2000577 +name: regulation of ATP-dependent microtubule motor activity, minus-end-directed +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed." [GOC:kmv, GOC:vw] +synonym: "regulation of kinesin ATP phosphohydrolase (minus-end-directed)" EXACT [GOC:obol] +synonym: "regulation of minus-end-directed kinesin ATPase activity" RELATED [GOC:obol] +synonym: "regulation of minus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0043462 ! regulation of ATPase activity +is_a: GO:2000574 ! regulation of microtubule motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +relationship: regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +created_by: bf +creation_date: 2011-04-05T08:37:52Z + +[Term] +id: GO:2000578 +name: negative regulation of ATP-dependent microtubule motor activity, minus-end-directed +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed." [GOC:kmv, GOC:vw] +synonym: "negative regulation of kinesin ATP phosphohydrolase (minus-end-directed)" EXACT [GOC:obol] +synonym: "negative regulation of minus-end-directed kinesin ATPase activity" EXACT [GOC:obol] +synonym: "negative regulation of minus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:2000575 ! negative regulation of microtubule motor activity +is_a: GO:2000577 ! regulation of ATP-dependent microtubule motor activity, minus-end-directed +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +relationship: negatively_regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +created_by: bf +creation_date: 2011-04-05T08:37:57Z + +[Term] +id: GO:2000579 +name: positive regulation of ATP-dependent microtubule motor activity, minus-end-directed +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed." [GOC:kmv, GOC:vw] +synonym: "positive regulation of kinesin ATP phosphohydrolase (minus-end-directed)" EXACT [GOC:obol] +synonym: "positive regulation of minus-end-directed kinesin ATPase activity" EXACT [GOC:obol] +synonym: "positive regulation of minus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:2000576 ! positive regulation of microtubule motor activity +is_a: GO:2000577 ! regulation of ATP-dependent microtubule motor activity, minus-end-directed +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +relationship: positively_regulates GO:0008569 ! ATP-dependent microtubule motor activity, minus-end-directed +created_by: bf +creation_date: 2011-04-05T08:38:01Z + +[Term] +id: GO:2000580 +name: regulation of ATP-dependent microtubule motor activity, plus-end-directed +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed." [GOC:kmv, GOC:vw] +synonym: "regulation of kinesin activity" RELATED [GOC:obol] +synonym: "regulation of kinesin ATP phosphohydrolase (plus-end-directed)" EXACT [GOC:obol] +synonym: "regulation of plus-end-directed kinesin ATPase activity" EXACT [GOC:obol] +synonym: "regulation of plus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0043462 ! regulation of ATPase activity +is_a: GO:2000574 ! regulation of microtubule motor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +relationship: regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +created_by: bf +creation_date: 2011-04-05T08:39:43Z + +[Term] +id: GO:2000581 +name: negative regulation of ATP-dependent microtubule motor activity, plus-end-directed +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed." [GOC:kmv, GOC:vw] +synonym: "negative regulation of kinesin activity" RELATED [GOC:obol] +synonym: "negative regulation of kinesin ATP phosphohydrolase (plus-end-directed)" EXACT [GOC:obol] +synonym: "negative regulation of plus-end-directed kinesin ATPase activity" EXACT [GOC:obol] +synonym: "negative regulation of plus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0032780 ! negative regulation of ATPase activity +is_a: GO:2000575 ! negative regulation of microtubule motor activity +is_a: GO:2000580 ! regulation of ATP-dependent microtubule motor activity, plus-end-directed +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +relationship: negatively_regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +created_by: bf +creation_date: 2011-04-05T08:39:49Z + +[Term] +id: GO:2000582 +name: positive regulation of ATP-dependent microtubule motor activity, plus-end-directed +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed." [GOC:kmv, GOC:vw] +synonym: "positive regulation of kinesin activity" RELATED [GOC:obol] +synonym: "positive regulation of kinesin ATP phosphohydrolase (plus-end-directed)" EXACT [GOC:obol] +synonym: "positive regulation of plus-end-directed kinesin ATPase activity" EXACT [GOC:obol] +synonym: "positive regulation of plus-end-directed microtubule motor activity" BROAD [] +is_a: GO:0032781 ! positive regulation of ATPase activity +is_a: GO:2000576 ! positive regulation of microtubule motor activity +is_a: GO:2000580 ! regulation of ATP-dependent microtubule motor activity, plus-end-directed +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +relationship: positively_regulates GO:0008574 ! ATP-dependent microtubule motor activity, plus-end-directed +created_by: bf +creation_date: 2011-04-05T08:39:52Z + +[Term] +id: GO:2000583 +name: regulation of platelet-derived growth factor receptor-alpha signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway." [GOC:obol] +synonym: "regulation of alphaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "regulation of PDGF receptor-alpha signaling pathway" EXACT [GOC:obol] +synonym: "regulation of PDGFR-alpha signaling pathway" RELATED [GOC:obol] +synonym: "regulation of platelet-derived growth factor receptor-alpha signalling pathway" EXACT [GOC:mah] +is_a: GO:0010640 ! regulation of platelet-derived growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +relationship: regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +created_by: bf +creation_date: 2011-04-07T03:26:25Z + +[Term] +id: GO:2000584 +name: negative regulation of platelet-derived growth factor receptor-alpha signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway." [GOC:obol, GOC:yaf] +synonym: "negative regulation of alphaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of PDGF receptor-alpha signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of PDGFR-alpha signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of platelet-derived growth factor receptor-alpha signalling pathway" EXACT [GOC:mah] +is_a: GO:0010642 ! negative regulation of platelet-derived growth factor receptor signaling pathway +is_a: GO:2000583 ! regulation of platelet-derived growth factor receptor-alpha signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +relationship: negatively_regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +created_by: bf +creation_date: 2011-04-07T03:26:31Z + +[Term] +id: GO:2000585 +name: positive regulation of platelet-derived growth factor receptor-alpha signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway." [GOC:obol] +synonym: "positive regulation of alphaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of PDGF receptor-alpha signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of PDGFR-alpha signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of platelet-derived growth factor receptor-alpha signalling pathway" EXACT [GOC:mah] +is_a: GO:0010641 ! positive regulation of platelet-derived growth factor receptor signaling pathway +is_a: GO:2000583 ! regulation of platelet-derived growth factor receptor-alpha signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +relationship: positively_regulates GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway +created_by: bf +creation_date: 2011-04-07T03:26:35Z + +[Term] +id: GO:2000586 +name: regulation of platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway." [GOC:obol] +synonym: "regulation of betaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "regulation of PDGF receptor-beta signaling pathway" EXACT [GOC:obol] +synonym: "regulation of PDGFR-beta signaling pathway" EXACT [GOC:obol] +synonym: "regulation of platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +is_a: GO:0010640 ! regulation of platelet-derived growth factor receptor signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +relationship: regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +created_by: bf +creation_date: 2011-04-07T03:27:48Z + +[Term] +id: GO:2000587 +name: negative regulation of platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway." [GOC:obol] +synonym: "negative regulation of betaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of PDGF receptor-beta signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of PDGFR-beta signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +is_a: GO:0010642 ! negative regulation of platelet-derived growth factor receptor signaling pathway +is_a: GO:2000586 ! regulation of platelet-derived growth factor receptor-beta signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +relationship: negatively_regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +created_by: bf +creation_date: 2011-04-07T03:27:54Z + +[Term] +id: GO:2000588 +name: positive regulation of platelet-derived growth factor receptor-beta signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway." [GOC:obol] +synonym: "positive regulation of betaPDGF receptor signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of PDGF receptor-beta signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of PDGFR-beta signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of platelet-derived growth factor receptor-beta signalling pathway" EXACT [GOC:mah] +is_a: GO:0010641 ! positive regulation of platelet-derived growth factor receptor signaling pathway +is_a: GO:2000586 ! regulation of platelet-derived growth factor receptor-beta signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +relationship: positively_regulates GO:0035791 ! platelet-derived growth factor receptor-beta signaling pathway +created_by: bf +creation_date: 2011-04-07T03:27:58Z + +[Term] +id: GO:2000589 +name: regulation of metanephric mesenchymal cell migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration." [GOC:obol] +synonym: "regulation of metanephric mesenchyme chemotaxis" RELATED [GOC:obol] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0072215 ! regulation of metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035789 ! metanephric mesenchymal cell migration +relationship: regulates GO:0035789 ! metanephric mesenchymal cell migration +created_by: bf +creation_date: 2011-04-07T03:29:43Z + +[Term] +id: GO:2000590 +name: negative regulation of metanephric mesenchymal cell migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration." [GOC:obol] +synonym: "negative regulation of metanephric mesenchyme chemotaxis" RELATED [GOC:obol] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:2000589 ! regulation of metanephric mesenchymal cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035789 ! metanephric mesenchymal cell migration +relationship: negatively_regulates GO:0035789 ! metanephric mesenchymal cell migration +created_by: bf +creation_date: 2011-04-07T03:29:49Z + +[Term] +id: GO:2000591 +name: positive regulation of metanephric mesenchymal cell migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "positive regulation of metanephric mesenchyme chemotaxis" RELATED [GOC:obol] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:2000589 ! regulation of metanephric mesenchymal cell migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035789 ! metanephric mesenchymal cell migration +relationship: positively_regulates GO:0035789 ! metanephric mesenchymal cell migration +created_by: bf +creation_date: 2011-04-07T03:29:53Z + +[Term] +id: GO:2000592 +name: regulation of metanephric DCT cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation." [GOC:obol] +synonym: "regulation of metanephric distal convoluted tubule cell differentiation" EXACT [GOC:obol] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0072215 ! regulation of metanephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072240 ! metanephric DCT cell differentiation +relationship: regulates GO:0072240 ! metanephric DCT cell differentiation +created_by: yaf +creation_date: 2011-04-11T01:40:33Z + +[Term] +id: GO:2000593 +name: negative regulation of metanephric DCT cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation." [GOC:obol] +synonym: "negative regulation of metanephric distal convoluted tubule cell differentiation" EXACT [GOC:obol] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:2000592 ! regulation of metanephric DCT cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072240 ! metanephric DCT cell differentiation +relationship: negatively_regulates GO:0072240 ! metanephric DCT cell differentiation +created_by: yaf +creation_date: 2011-04-11T01:40:38Z + +[Term] +id: GO:2000594 +name: positive regulation of metanephric DCT cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation." [GOC:obol] +synonym: "positive regulation of metanephric distal convoluted tubule cell differentiation" EXACT [GOC:obol] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:2000592 ! regulation of metanephric DCT cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072240 ! metanephric DCT cell differentiation +relationship: positively_regulates GO:0072240 ! metanephric DCT cell differentiation +created_by: yaf +creation_date: 2011-04-11T01:40:41Z + +[Term] +id: GO:2000595 +name: regulation of optic nerve formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of optic nerve formation." [GOC:obol] +synonym: "regulation of CN II biosynthesis" RELATED [GOC:obol] +synonym: "regulation of CN II formation" RELATED [GOC:obol] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0051960 ! regulation of nervous system development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0021634 ! optic nerve formation +relationship: regulates GO:0021634 ! optic nerve formation +created_by: yaf +creation_date: 2011-04-11T03:41:30Z + +[Term] +id: GO:2000596 +name: negative regulation of optic nerve formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation." [GOC:obol] +synonym: "negative regulation of CN II biosynthesis" RELATED [GOC:obol] +synonym: "negative regulation of CN II formation" RELATED [GOC:obol] +is_a: GO:0051961 ! negative regulation of nervous system development +is_a: GO:2000595 ! regulation of optic nerve formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021634 ! optic nerve formation +relationship: negatively_regulates GO:0021634 ! optic nerve formation +created_by: yaf +creation_date: 2011-04-11T03:41:35Z + +[Term] +id: GO:2000597 +name: positive regulation of optic nerve formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of optic nerve formation." [GOC:obol] +synonym: "positive regulation of CN II biosynthesis" RELATED [GOC:obol] +synonym: "positive regulation of CN II formation" RELATED [GOC:obol] +is_a: GO:0051962 ! positive regulation of nervous system development +is_a: GO:2000595 ! regulation of optic nerve formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0021634 ! optic nerve formation +relationship: positively_regulates GO:0021634 ! optic nerve formation +created_by: yaf +creation_date: 2011-04-11T03:41:39Z + +[Term] +id: GO:2000601 +name: positive regulation of Arp2/3 complex-mediated actin nucleation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation." [PMID:21454476] +synonym: "positive regulation of actin filament branch nucleation" EXACT [GOC:obol] +synonym: "positive regulation of branched actin filament nucleation" EXACT [GOC:obol] +is_a: GO:0034315 ! regulation of Arp2/3 complex-mediated actin nucleation +is_a: GO:0051127 ! positive regulation of actin nucleation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation +relationship: positively_regulates GO:0034314 ! Arp2/3 complex-mediated actin nucleation +created_by: bf +creation_date: 2011-04-14T12:35:44Z + +[Term] +id: GO:2000602 +name: obsolete regulation of interphase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle." [GOC:obol] +comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated. +synonym: "regulation of interphase of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: pr +creation_date: 2011-04-15T03:52:25Z + +[Term] +id: GO:2000603 +name: regulation of secondary growth +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary growth." [GOC:obol] +is_a: GO:0040008 ! regulation of growth +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080117 ! secondary growth +relationship: regulates GO:0080117 ! secondary growth +created_by: tb +creation_date: 2011-04-15T10:30:44Z + +[Term] +id: GO:2000604 +name: negative regulation of secondary growth +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth." [GOC:obol] +is_a: GO:0045926 ! negative regulation of growth +is_a: GO:2000603 ! regulation of secondary growth +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0080117 ! secondary growth +relationship: negatively_regulates GO:0080117 ! secondary growth +created_by: tb +creation_date: 2011-04-15T10:30:47Z + +[Term] +id: GO:2000605 +name: positive regulation of secondary growth +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of secondary growth." [GOC:obol] +is_a: GO:0045927 ! positive regulation of growth +is_a: GO:2000603 ! regulation of secondary growth +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0080117 ! secondary growth +relationship: positively_regulates GO:0080117 ! secondary growth +created_by: tb +creation_date: 2011-04-15T10:30:49Z + +[Term] +id: GO:2000606 +name: regulation of cell proliferation involved in mesonephros development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061209 ! cell proliferation involved in mesonephros development +relationship: regulates GO:0061209 ! cell proliferation involved in mesonephros development +created_by: yaf +creation_date: 2011-04-18T08:42:19Z + +[Term] +id: GO:2000607 +name: negative regulation of cell proliferation involved in mesonephros development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development +is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development +relationship: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development +created_by: yaf +creation_date: 2011-04-18T08:42:23Z + +[Term] +id: GO:2000608 +name: positive regulation of cell proliferation involved in mesonephros development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development +is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development +relationship: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development +created_by: yaf +creation_date: 2011-04-18T08:42:25Z + +[Term] +id: GO:2000609 +name: regulation of thyroid hormone generation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thyroid hormone generation." [GOC:obol] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0032350 ! regulation of hormone metabolic process +is_a: GO:0051171 ! regulation of nitrogen compound metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006590 ! thyroid hormone generation +relationship: regulates GO:0006590 ! thyroid hormone generation +created_by: yaf +creation_date: 2011-04-18T10:12:14Z + +[Term] +id: GO:2000610 +name: negative regulation of thyroid hormone generation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation." [GOC:obol] +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:0032351 ! negative regulation of hormone metabolic process +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:2000609 ! regulation of thyroid hormone generation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006590 ! thyroid hormone generation +relationship: negatively_regulates GO:0006590 ! thyroid hormone generation +created_by: yaf +creation_date: 2011-04-18T10:12:19Z + +[Term] +id: GO:2000611 +name: positive regulation of thyroid hormone generation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thyroid hormone generation." [GOC:obol] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:0032352 ! positive regulation of hormone metabolic process +is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process +is_a: GO:2000609 ! regulation of thyroid hormone generation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006590 ! thyroid hormone generation +relationship: positively_regulates GO:0006590 ! thyroid hormone generation +created_by: yaf +creation_date: 2011-04-18T10:12:22Z + +[Term] +id: GO:2000612 +name: regulation of thyroid-stimulating hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion." [GOC:obol] +synonym: "regulation of thyroid stimulating hormone secretion" EXACT [GOC:obol] +synonym: "regulation of TSH secretion" EXACT [GOC:obol] +is_a: GO:0090276 ! regulation of peptide hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070460 ! thyroid-stimulating hormone secretion +relationship: regulates GO:0070460 ! thyroid-stimulating hormone secretion +created_by: yaf +creation_date: 2011-04-18T12:56:16Z + +[Term] +id: GO:2000613 +name: negative regulation of thyroid-stimulating hormone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion." [GOC:obol] +synonym: "negative regulation of thyroid stimulating hormone secretion" EXACT [GOC:obol] +synonym: "negative regulation of TSH secretion" EXACT [GOC:obol] +is_a: GO:0090278 ! negative regulation of peptide hormone secretion +is_a: GO:2000612 ! regulation of thyroid-stimulating hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070460 ! thyroid-stimulating hormone secretion +relationship: negatively_regulates GO:0070460 ! thyroid-stimulating hormone secretion +created_by: yaf +creation_date: 2011-04-18T12:56:20Z + +[Term] +id: GO:2000614 +name: positive regulation of thyroid-stimulating hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion." [GOC:obol] +synonym: "positive regulation of thyroid stimulating hormone secretion" EXACT [GOC:obol] +synonym: "positive regulation of TSH secretion" EXACT [GOC:obol] +is_a: GO:0090277 ! positive regulation of peptide hormone secretion +is_a: GO:2000612 ! regulation of thyroid-stimulating hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070460 ! thyroid-stimulating hormone secretion +relationship: positively_regulates GO:0070460 ! thyroid-stimulating hormone secretion +created_by: yaf +creation_date: 2011-04-18T12:56:22Z + +[Term] +id: GO:2000615 +name: regulation of histone H3-K9 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation." [GOC:BHF] +synonym: "regulation of histone H3 acetylation at K9" EXACT [GOC:obol] +synonym: "regulation of histone H3K9 acetylation" EXACT [GOC:obol] +is_a: GO:0035065 ! regulation of histone acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043970 ! histone H3-K9 acetylation +relationship: regulates GO:0043970 ! histone H3-K9 acetylation +created_by: vk +creation_date: 2011-04-18T03:15:59Z + +[Term] +id: GO:2000616 +name: negative regulation of histone H3-K9 acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation." [GOC:BHF] +synonym: "negative regulation of histone H3 acetylation at K9" EXACT [GOC:obol] +synonym: "negative regulation of histone H3K9 acetylation" EXACT [GOC:obol] +is_a: GO:0035067 ! negative regulation of histone acetylation +is_a: GO:2000615 ! regulation of histone H3-K9 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043970 ! histone H3-K9 acetylation +relationship: negatively_regulates GO:0043970 ! histone H3-K9 acetylation +created_by: vk +creation_date: 2011-04-18T03:16:04Z + +[Term] +id: GO:2000617 +name: positive regulation of histone H3-K9 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation." [GOC:BHF] +synonym: "positive regulation of histone H3 acetylation at K9" EXACT [GOC:obol] +synonym: "positive regulation of histone H3K9 acetylation" EXACT [GOC:obol] +is_a: GO:0035066 ! positive regulation of histone acetylation +is_a: GO:2000615 ! regulation of histone H3-K9 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043970 ! histone H3-K9 acetylation +relationship: positively_regulates GO:0043970 ! histone H3-K9 acetylation +created_by: vk +creation_date: 2011-04-18T03:16:07Z + +[Term] +id: GO:2000618 +name: regulation of histone H4-K16 acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation." [GOC:BHF] +synonym: "regulation of histone H4 acetylation at K16" EXACT [GOC:obol] +is_a: GO:0090239 ! regulation of histone H4 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0043984 ! histone H4-K16 acetylation +relationship: regulates GO:0043984 ! histone H4-K16 acetylation +created_by: vk +creation_date: 2011-04-18T03:19:23Z + +[Term] +id: GO:2000619 +name: negative regulation of histone H4-K16 acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation." [GOC:BHF] +synonym: "negative regulation of histone H4 acetylation at K16" EXACT [GOC:obol] +is_a: GO:0090241 ! negative regulation of histone H4 acetylation +is_a: GO:2000618 ! regulation of histone H4-K16 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043984 ! histone H4-K16 acetylation +relationship: negatively_regulates GO:0043984 ! histone H4-K16 acetylation +created_by: vk +creation_date: 2011-04-18T03:19:27Z + +[Term] +id: GO:2000620 +name: positive regulation of histone H4-K16 acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation." [GOC:BHF] +synonym: "positive regulation of histone H4 acetylation at K16" EXACT [GOC:obol] +is_a: GO:0090240 ! positive regulation of histone H4 acetylation +is_a: GO:2000618 ! regulation of histone H4-K16 acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0043984 ! histone H4-K16 acetylation +relationship: positively_regulates GO:0043984 ! histone H4-K16 acetylation +created_by: vk +creation_date: 2011-04-18T03:19:30Z + +[Term] +id: GO:2000621 +name: regulation of DNA replication termination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of DNA replication termination." [GOC:obol] +is_a: GO:0051052 ! regulation of DNA metabolic process +is_a: GO:0090329 ! regulation of DNA-dependent DNA replication +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006274 ! DNA replication termination +relationship: regulates GO:0006274 ! DNA replication termination +created_by: pr +creation_date: 2011-04-18T03:26:23Z + +[Term] +id: GO:2000622 +name: regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." [GOC:obol] +synonym: "regulation of mRNA breakdown, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "regulation of mRNA catabolic process, nonsense-mediated" EXACT [GOC:obol] +synonym: "regulation of mRNA catabolism, nonsense-mediated" EXACT [GOC:obol] +synonym: "regulation of mRNA degradation, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "regulation of nonsense-mediated mRNA decay" EXACT [GOC:obol] +synonym: "regulation of nuclear mRNA catabolic process, nonsense-mediated decay" EXACT [GOC:obol] +is_a: GO:0061013 ! regulation of mRNA catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +relationship: regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +created_by: pr +creation_date: 2011-04-18T03:32:42Z + +[Term] +id: GO:2000623 +name: negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." [GOC:obol] +synonym: "negative regulation of mRNA breakdown, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "negative regulation of mRNA catabolic process, nonsense-mediated" EXACT [GOC:obol] +synonym: "negative regulation of mRNA catabolism, nonsense-mediated" EXACT [GOC:obol] +synonym: "negative regulation of mRNA degradation, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "negative regulation of nonsense-mediated mRNA decay" EXACT [GOC:obol] +synonym: "negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay" EXACT [GOC:obol] +is_a: GO:1902373 ! negative regulation of mRNA catabolic process +is_a: GO:2000622 ! regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +relationship: negatively_regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +created_by: pr +creation_date: 2011-04-18T03:32:46Z + +[Term] +id: GO:2000624 +name: positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." [GOC:obol] +synonym: "positive regulation of mRNA breakdown, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "positive regulation of mRNA catabolic process, nonsense-mediated" EXACT [GOC:obol] +synonym: "positive regulation of mRNA catabolism, nonsense-mediated" EXACT [GOC:obol] +synonym: "positive regulation of mRNA degradation, nonsense-mediated decay" EXACT [GOC:obol] +synonym: "positive regulation of nonsense-mediated mRNA decay" EXACT [GOC:obol] +synonym: "positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay" EXACT [GOC:obol] +is_a: GO:0061014 ! positive regulation of mRNA catabolic process +is_a: GO:2000622 ! regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +relationship: positively_regulates GO:0000184 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay +created_by: pr +creation_date: 2011-04-18T03:32:49Z + +[Term] +id: GO:2000625 +name: regulation of miRNA catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of miRNA catabolic process." [GOC:dph] +synonym: "regulation of microRNA catabolic process" EXACT [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:2000628 ! regulation of miRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010587 ! miRNA catabolic process +relationship: regulates GO:0010587 ! miRNA catabolic process +created_by: dph +creation_date: 2011-04-18T03:46:35Z + +[Term] +id: GO:2000626 +name: negative regulation of miRNA catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process." [GOC:dph] +synonym: "negative regulation of microRNA catabolic process" EXACT [GOC:obol] +is_a: GO:1902369 ! negative regulation of RNA catabolic process +is_a: GO:2000625 ! regulation of miRNA catabolic process +is_a: GO:2000629 ! negative regulation of miRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010587 ! miRNA catabolic process +relationship: negatively_regulates GO:0010587 ! miRNA catabolic process +created_by: dph +creation_date: 2011-04-18T03:46:39Z + +[Term] +id: GO:2000627 +name: positive regulation of miRNA catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of miRNA catabolic process." [GOC:dph] +synonym: "positive regulation of microRNA catabolic process" EXACT [GOC:obol] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2000625 ! regulation of miRNA catabolic process +is_a: GO:2000630 ! positive regulation of miRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010587 ! miRNA catabolic process +relationship: positively_regulates GO:0010587 ! miRNA catabolic process +created_by: dph +creation_date: 2011-04-18T03:46:42Z + +[Term] +id: GO:2000628 +name: regulation of miRNA metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of miRNA metabolic process." [GOC:dph] +synonym: "regulation of microRNA metabolic process" EXACT [GOC:obol] +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010586 ! miRNA metabolic process +relationship: regulates GO:0010586 ! miRNA metabolic process +created_by: dph +creation_date: 2011-04-18T03:47:54Z + +[Term] +id: GO:2000629 +name: negative regulation of miRNA metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process." [GOC:dph] +synonym: "negative regulation of microRNA metabolic process" EXACT [GOC:obol] +is_a: GO:0051253 ! negative regulation of RNA metabolic process +is_a: GO:2000628 ! regulation of miRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010586 ! miRNA metabolic process +relationship: negatively_regulates GO:0010586 ! miRNA metabolic process +created_by: dph +creation_date: 2011-04-18T03:47:58Z + +[Term] +id: GO:2000630 +name: positive regulation of miRNA metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of miRNA metabolic process." [GOC:dph] +synonym: "positive regulation of microRNA metabolic process" EXACT [GOC:obol] +is_a: GO:0051254 ! positive regulation of RNA metabolic process +is_a: GO:2000628 ! regulation of miRNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010586 ! miRNA metabolic process +relationship: positively_regulates GO:0010586 ! miRNA metabolic process +created_by: dph +creation_date: 2011-04-18T03:48:01Z + +[Term] +id: GO:2000631 +name: regulation of pre-miRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pre-microRNA processing." [GOC:dph, GOC:sl] +synonym: "regulation of pre-microRNA processing" EXACT [] +is_a: GO:1903798 ! regulation of production of miRNAs involved in gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031054 ! pre-miRNA processing +relationship: regulates GO:0031054 ! pre-miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:16Z + +[Term] +id: GO:2000632 +name: negative regulation of pre-miRNA processing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing." [GOC:dph, GOC:sl] +synonym: "negative regulation of pre-microRNA processing" EXACT [GOC:obol] +is_a: GO:1903799 ! negative regulation of production of miRNAs involved in gene silencing by miRNA +is_a: GO:2000631 ! regulation of pre-miRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031054 ! pre-miRNA processing +relationship: negatively_regulates GO:0031054 ! pre-miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:19Z + +[Term] +id: GO:2000633 +name: positive regulation of pre-miRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pre-microRNA processing." [GOC:dph, GOC:sl] +synonym: "positive regulation of pre-microRNA processing" EXACT [GOC:obol] +is_a: GO:1903800 ! positive regulation of production of miRNAs involved in gene silencing by miRNA +is_a: GO:2000631 ! regulation of pre-miRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031054 ! pre-miRNA processing +relationship: positively_regulates GO:0031054 ! pre-miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:22Z + +[Term] +id: GO:2000634 +name: regulation of primary miRNA processing +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of primary microRNA processing." [GOC:dph, GOC:sl] +synonym: "regulation of pri-miRNA processing" EXACT [GOC:obol] +synonym: "regulation of primary microRNA processing" EXACT [GOC:obol] +is_a: GO:1903798 ! regulation of production of miRNAs involved in gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031053 ! primary miRNA processing +relationship: regulates GO:0031053 ! primary miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:50Z + +[Term] +id: GO:2000635 +name: negative regulation of primary miRNA processing +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing." [GOC:dph, GOC:sl] +synonym: "negative regulation of pri-miRNA processing" EXACT [GOC:obol] +synonym: "negative regulation of primary microRNA processing" EXACT [GOC:obol] +is_a: GO:1903799 ! negative regulation of production of miRNAs involved in gene silencing by miRNA +is_a: GO:2000634 ! regulation of primary miRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0031053 ! primary miRNA processing +relationship: negatively_regulates GO:0031053 ! primary miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:53Z + +[Term] +id: GO:2000636 +name: positive regulation of primary miRNA processing +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of primary microRNA processing." [GOC:dph, GOC:sl] +synonym: "positive regulation of pri-miRNA processing" EXACT [GOC:obol] +synonym: "positive regulation of primary microRNA processing" EXACT [GOC:obol] +is_a: GO:1903800 ! positive regulation of production of miRNAs involved in gene silencing by miRNA +is_a: GO:2000634 ! regulation of primary miRNA processing +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0031053 ! primary miRNA processing +relationship: positively_regulates GO:0031053 ! primary miRNA processing +created_by: dph +creation_date: 2011-04-18T03:50:56Z + +[Term] +id: GO:2000637 +name: positive regulation of gene silencing by miRNA +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA." [GOC:dph] +synonym: "positive regulation of gene silencing by microRNA" RELATED [GOC:pr] +synonym: "positive regulation of microRNA-mediated gene silencing" EXACT [GOC:obol] +synonym: "positive regulation of miRNA-mediated gene silencing" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0060148 ! positive regulation of posttranscriptional gene silencing +is_a: GO:0060964 ! regulation of gene silencing by miRNA +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035195 ! gene silencing by miRNA +relationship: positively_regulates GO:0035195 ! gene silencing by miRNA +created_by: dph +creation_date: 2011-04-18T03:51:24Z + +[Term] +id: GO:2000638 +name: regulation of SREBP signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of the SREBP signaling pathway." [GOC:BHF] +synonym: "regulation of SREBP-mediated signaling pathway" EXACT [GOC:bf, GOC:vw] +synonym: "regulation of SREBP-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032933 ! SREBP signaling pathway +relationship: regulates GO:0032933 ! SREBP signaling pathway +created_by: vk +creation_date: 2011-04-20T02:45:59Z + +[Term] +id: GO:2000639 +name: negative regulation of SREBP signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway." [GOC:BHF] +synonym: "negative regulation of SREBP-mediated signaling pathway" EXACT [GOC:bf, GOC:vw] +synonym: "negative regulation of SREBP-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:2000638 ! regulation of SREBP signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032933 ! SREBP signaling pathway +relationship: negatively_regulates GO:0032933 ! SREBP signaling pathway +created_by: vk +creation_date: 2011-04-20T02:46:02Z + +[Term] +id: GO:2000640 +name: positive regulation of SREBP signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway." [GOC:BHF] +synonym: "positive regulation of SREBP-mediated signaling pathway" EXACT [GOC:bf, GOC:vw] +synonym: "positive regulation of SREBP-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +is_a: GO:2000638 ! regulation of SREBP signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032933 ! SREBP signaling pathway +relationship: positively_regulates GO:0032933 ! SREBP signaling pathway +created_by: vk +creation_date: 2011-04-20T02:46:05Z + +[Term] +id: GO:2000641 +name: regulation of early endosome to late endosome transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of early endosome to late endosome transport." [GOC:BHF] +is_a: GO:0060627 ! regulation of vesicle-mediated transport +is_a: GO:1903649 ! regulation of cytoplasmic transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045022 ! early endosome to late endosome transport +relationship: regulates GO:0045022 ! early endosome to late endosome transport +created_by: vk +creation_date: 2011-04-21T11:20:02Z + +[Term] +id: GO:2000642 +name: negative regulation of early endosome to late endosome transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport." [GOC:BHF] +is_a: GO:1903650 ! negative regulation of cytoplasmic transport +is_a: GO:2000641 ! regulation of early endosome to late endosome transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045022 ! early endosome to late endosome transport +relationship: negatively_regulates GO:0045022 ! early endosome to late endosome transport +created_by: vk +creation_date: 2011-04-21T11:20:06Z + +[Term] +id: GO:2000643 +name: positive regulation of early endosome to late endosome transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport." [GOC:BHF] +is_a: GO:1903651 ! positive regulation of cytoplasmic transport +is_a: GO:2000641 ! regulation of early endosome to late endosome transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045022 ! early endosome to late endosome transport +relationship: positively_regulates GO:0045022 ! early endosome to late endosome transport +created_by: vk +creation_date: 2011-04-21T11:20:09Z + +[Term] +id: GO:2000644 +name: regulation of receptor catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of receptor catabolic process." [GOC:BHF] +synonym: "regulation of receptor breakdown" EXACT [GOC:obol] +synonym: "regulation of receptor catabolism" EXACT [GOC:obol] +synonym: "regulation of receptor degradation" EXACT [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032801 ! receptor catabolic process +relationship: regulates GO:0032801 ! receptor catabolic process +created_by: vk +creation_date: 2011-04-21T11:20:18Z + +[Term] +id: GO:2000645 +name: negative regulation of receptor catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process." [GOC:BHF] +synonym: "negative regulation of receptor breakdown" EXACT [GOC:obol] +synonym: "negative regulation of receptor catabolism" EXACT [GOC:obol] +synonym: "negative regulation of receptor degradation" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:2000644 ! regulation of receptor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032801 ! receptor catabolic process +relationship: negatively_regulates GO:0032801 ! receptor catabolic process +created_by: vk +creation_date: 2011-04-21T11:20:22Z + +[Term] +id: GO:2000646 +name: positive regulation of receptor catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of receptor catabolic process." [GOC:BHF] +synonym: "positive regulation of receptor breakdown" EXACT [GOC:obol] +synonym: "positive regulation of receptor catabolism" EXACT [GOC:obol] +synonym: "positive regulation of receptor degradation" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2000644 ! regulation of receptor catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032801 ! receptor catabolic process +relationship: positively_regulates GO:0032801 ! receptor catabolic process +created_by: vk +creation_date: 2011-04-21T11:20:25Z + +[Term] +id: GO:2000647 +name: negative regulation of stem cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:0072091 ! regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072089 ! stem cell proliferation +relationship: negatively_regulates GO:0072089 ! stem cell proliferation +created_by: dph +creation_date: 2011-04-27T01:04:22Z + +[Term] +id: GO:2000648 +name: positive regulation of stem cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph] +is_a: GO:0008284 ! positive regulation of cell population proliferation +is_a: GO:0072091 ! regulation of stem cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072089 ! stem cell proliferation +relationship: positively_regulates GO:0072089 ! stem cell proliferation +created_by: dph +creation_date: 2011-04-27T01:04:25Z + +[Term] +id: GO:2000649 +name: regulation of sodium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] +synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1902305 ! regulation of sodium ion transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015081 ! sodium ion transmembrane transporter activity +relationship: regulates GO:0015081 ! sodium ion transmembrane transporter activity +created_by: yaf +creation_date: 2011-04-28T08:42:53Z + +[Term] +id: GO:2000650 +name: negative regulation of sodium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] +synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity +relationship: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity +created_by: yaf +creation_date: 2011-04-28T08:42:57Z + +[Term] +id: GO:2000651 +name: positive regulation of sodium ion transmembrane transporter activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] +synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport +is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity +relationship: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity +created_by: yaf +creation_date: 2011-04-28T08:43:00Z + +[Term] +id: GO:2000652 +name: regulation of secondary cell wall biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis." [GOC:obol] +synonym: "regulation of cellulose and pectin-containing secondary cell wall biogenesis" EXACT [GOC:obol] +synonym: "regulation of plant-type secondary cell wall biogenesis" EXACT [GOC:obol] +synonym: "regulation of secondary cell wall anabolism" RELATED [GOC:obol] +synonym: "regulation of secondary cell wall biosynthetic process" RELATED [GOC:obol] +synonym: "regulation of secondary cell wall formation" RELATED [GOC:obol] +synonym: "regulation of secondary cell wall synthesis" RELATED [GOC:obol] +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:1903338 ! regulation of cell wall organization or biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009834 ! plant-type secondary cell wall biogenesis +relationship: regulates GO:0009834 ! plant-type secondary cell wall biogenesis +created_by: dhl +creation_date: 2011-04-29T08:50:02Z + +[Term] +id: GO:2000653 +name: regulation of genetic imprinting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of genetic imprinting." [GOC:BHF] +synonym: "regulation of DNA imprinting" EXACT [GOC:obol] +is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071514 ! genetic imprinting +relationship: regulates GO:0071514 ! genetic imprinting +created_by: vk +creation_date: 2011-04-30T02:42:19Z + +[Term] +id: GO:2000654 +name: regulation of cellular response to testosterone stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus." [GOC:BHF] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071394 ! cellular response to testosterone stimulus +relationship: regulates GO:0071394 ! cellular response to testosterone stimulus +created_by: vk +creation_date: 2011-05-02T03:23:56Z + +[Term] +id: GO:2000655 +name: negative regulation of cellular response to testosterone stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus." [GOC:BHF] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2000654 ! regulation of cellular response to testosterone stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071394 ! cellular response to testosterone stimulus +relationship: negatively_regulates GO:0071394 ! cellular response to testosterone stimulus +created_by: vk +creation_date: 2011-05-02T03:23:59Z + +[Term] +id: GO:2000656 +name: regulation of apolipoprotein binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034185 ! apolipoprotein binding +relationship: regulates GO:0034185 ! apolipoprotein binding +created_by: vk +creation_date: 2011-05-02T05:33:41Z + +[Term] +id: GO:2000657 +name: negative regulation of apolipoprotein binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:2000656 ! regulation of apolipoprotein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034185 ! apolipoprotein binding +relationship: negatively_regulates GO:0034185 ! apolipoprotein binding +created_by: vk +creation_date: 2011-05-02T05:33:44Z + +[Term] +id: GO:2000658 +name: positive regulation of apolipoprotein binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apolipoprotein binding." [GOC:BHF] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:2000656 ! regulation of apolipoprotein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034185 ! apolipoprotein binding +relationship: positively_regulates GO:0034185 ! apolipoprotein binding +created_by: vk +creation_date: 2011-05-02T05:33:46Z + +[Term] +id: GO:2000659 +name: regulation of interleukin-1-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway." [GOC:obol] +synonym: "regulation of IL-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "regulation of IL-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "regulation of IL-1-mediated signaling pathway" EXACT [GOC:obol] +synonym: "regulation of interleukin-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "regulation of interleukin-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "regulation of interleukin-1-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001959 ! regulation of cytokine-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070498 ! interleukin-1-mediated signaling pathway +relationship: regulates GO:0070498 ! interleukin-1-mediated signaling pathway +created_by: dph +creation_date: 2011-05-03T07:13:31Z + +[Term] +id: GO:2000660 +name: negative regulation of interleukin-1-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway." [GOC:obol] +synonym: "negative regulation of IL-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of IL-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of IL-1-mediated signaling pathway" EXACT [GOC:obol] +synonym: "negative regulation of interleukin-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of interleukin-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of interleukin-1-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001960 ! negative regulation of cytokine-mediated signaling pathway +is_a: GO:2000659 ! regulation of interleukin-1-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0070498 ! interleukin-1-mediated signaling pathway +relationship: negatively_regulates GO:0070498 ! interleukin-1-mediated signaling pathway +created_by: dph +creation_date: 2011-05-03T07:13:37Z + +[Term] +id: GO:2000661 +name: positive regulation of interleukin-1-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway." [GOC:obol] +synonym: "positive regulation of IL-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of IL-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of IL-1-mediated signaling pathway" EXACT [GOC:obol] +synonym: "positive regulation of interleukin-1 alpha-mediated signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of interleukin-1 beta-mediated signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of interleukin-1-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0001961 ! positive regulation of cytokine-mediated signaling pathway +is_a: GO:2000659 ! regulation of interleukin-1-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0070498 ! interleukin-1-mediated signaling pathway +relationship: positively_regulates GO:0070498 ! interleukin-1-mediated signaling pathway +created_by: dph +creation_date: 2011-05-03T07:13:40Z + +[Term] +id: GO:2000662 +name: regulation of interleukin-5 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-5 secretion." [GOC:obol] +synonym: "regulation of IL-5 secretion" EXACT [GOC:obol] +is_a: GO:0032674 ! regulation of interleukin-5 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072603 ! interleukin-5 secretion +relationship: regulates GO:0072603 ! interleukin-5 secretion +created_by: yaf +creation_date: 2011-05-06T02:59:02Z + +[Term] +id: GO:2000663 +name: negative regulation of interleukin-5 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-5 secretion." [GOC:obol] +synonym: "negative regulation of IL-5 secretion" EXACT [GOC:obol] +is_a: GO:0032714 ! negative regulation of interleukin-5 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2000662 ! regulation of interleukin-5 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072603 ! interleukin-5 secretion +relationship: negatively_regulates GO:0072603 ! interleukin-5 secretion +created_by: yaf +creation_date: 2011-05-06T02:59:05Z + +[Term] +id: GO:2000664 +name: positive regulation of interleukin-5 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion." [GOC:obol] +synonym: "positive regulation of IL-5 secretion" EXACT [GOC:obol] +is_a: GO:0032754 ! positive regulation of interleukin-5 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2000662 ! regulation of interleukin-5 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072603 ! interleukin-5 secretion +relationship: positively_regulates GO:0072603 ! interleukin-5 secretion +created_by: yaf +creation_date: 2011-05-06T02:59:07Z + +[Term] +id: GO:2000665 +name: regulation of interleukin-13 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-13 secretion." [GOC:obol] +synonym: "regulation of IL-13 secretion" EXACT [GOC:obol] +is_a: GO:0032656 ! regulation of interleukin-13 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072611 ! interleukin-13 secretion +relationship: regulates GO:0072611 ! interleukin-13 secretion +created_by: yaf +creation_date: 2011-05-06T03:24:19Z + +[Term] +id: GO:2000666 +name: negative regulation of interleukin-13 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion." [GOC:obol] +synonym: "negative regulation of IL-13 secretion" EXACT [GOC:obol] +is_a: GO:0032696 ! negative regulation of interleukin-13 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2000665 ! regulation of interleukin-13 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072611 ! interleukin-13 secretion +relationship: negatively_regulates GO:0072611 ! interleukin-13 secretion +created_by: yaf +creation_date: 2011-05-06T03:24:22Z + +[Term] +id: GO:2000667 +name: positive regulation of interleukin-13 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion." [GOC:obol] +synonym: "positive regulation of IL-13 secretion" EXACT [GOC:obol] +is_a: GO:0032736 ! positive regulation of interleukin-13 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2000665 ! regulation of interleukin-13 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072611 ! interleukin-13 secretion +relationship: positively_regulates GO:0072611 ! interleukin-13 secretion +created_by: yaf +creation_date: 2011-05-06T03:24:25Z + +[Term] +id: GO:2000668 +name: regulation of dendritic cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "regulation of dendritic cell apoptosis" NARROW [] +is_a: GO:2000106 ! regulation of leukocyte apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097048 ! dendritic cell apoptotic process +relationship: regulates GO:0097048 ! dendritic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T07:34:16Z + +[Term] +id: GO:2000669 +name: negative regulation of dendritic cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "negative regulation of dendritic cell apoptosis" NARROW [] +is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process +is_a: GO:2000668 ! regulation of dendritic cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097048 ! dendritic cell apoptotic process +relationship: negatively_regulates GO:0097048 ! dendritic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T07:34:21Z + +[Term] +id: GO:2000670 +name: positive regulation of dendritic cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "positive regulation of dendritic cell apoptosis" NARROW [] +is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process +is_a: GO:2000668 ! regulation of dendritic cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097048 ! dendritic cell apoptotic process +relationship: positively_regulates GO:0097048 ! dendritic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T07:34:26Z + +[Term] +id: GO:2000671 +name: regulation of motor neuron apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol] +synonym: "regulation of motor neuron apoptosis" NARROW [] +is_a: GO:0043523 ! regulation of neuron apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097049 ! motor neuron apoptotic process +relationship: regulates GO:0097049 ! motor neuron apoptotic process +created_by: pr +creation_date: 2011-05-09T10:56:17Z + +[Term] +id: GO:2000672 +name: negative regulation of motor neuron apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol] +synonym: "negative regulation of motor neuron apoptosis" NARROW [] +is_a: GO:0043524 ! negative regulation of neuron apoptotic process +is_a: GO:2000671 ! regulation of motor neuron apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097049 ! motor neuron apoptotic process +relationship: negatively_regulates GO:0097049 ! motor neuron apoptotic process +created_by: pr +creation_date: 2011-05-09T10:56:21Z + +[Term] +id: GO:2000673 +name: positive regulation of motor neuron apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol] +synonym: "positive regulation of motor neuron apoptosis" NARROW [] +is_a: GO:0043525 ! positive regulation of neuron apoptotic process +is_a: GO:2000671 ! regulation of motor neuron apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097049 ! motor neuron apoptotic process +relationship: positively_regulates GO:0097049 ! motor neuron apoptotic process +created_by: pr +creation_date: 2011-05-09T10:56:24Z + +[Term] +id: GO:2000674 +name: regulation of type B pancreatic cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] +synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] +synonym: "regulation of type B pancreatic cell apoptosis" NARROW [] +is_a: GO:1904035 ! regulation of epithelial cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097050 ! type B pancreatic cell apoptotic process +relationship: regulates GO:0097050 ! type B pancreatic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T11:51:09Z + +[Term] +id: GO:2000675 +name: negative regulation of type B pancreatic cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] +synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] +synonym: "negative regulation of type B pancreatic cell apoptosis" NARROW [] +is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process +is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process +relationship: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T11:51:12Z + +[Term] +id: GO:2000676 +name: positive regulation of type B pancreatic cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] +synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] +synonym: "positive regulation of type B pancreatic cell apoptosis" NARROW [] +is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process +is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process +relationship: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process +created_by: pr +creation_date: 2011-05-09T11:51:15Z + +[Term] +id: GO:2000677 +name: regulation of transcription regulatory region DNA binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding." [GOC:obol] +is_a: GO:0051101 ! regulation of DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +relationship: regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: yaf +creation_date: 2011-05-09T03:28:11Z + +[Term] +id: GO:2000678 +name: negative regulation of transcription regulatory region DNA binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding." [GOC:obol] +is_a: GO:0043392 ! negative regulation of DNA binding +is_a: GO:2000677 ! regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +relationship: negatively_regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: yaf +creation_date: 2011-05-09T03:28:14Z + +[Term] +id: GO:2000679 +name: positive regulation of transcription regulatory region DNA binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding." [GOC:obol] +is_a: GO:0043388 ! positive regulation of DNA binding +is_a: GO:2000677 ! regulation of transcription regulatory region DNA binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +relationship: positively_regulates GO:0000976 ! transcription regulatory region sequence-specific DNA binding +created_by: yaf +creation_date: 2011-05-09T03:28:17Z + +[Term] +id: GO:2000680 +name: obsolete regulation of rubidium ion transport +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transport." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "regulation of Rb+ transport" EXACT [GOC:obol] +synonym: "regulation of rubidium cation transport" EXACT [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-10T10:54:31Z + +[Term] +id: GO:2000681 +name: obsolete negative regulation of rubidium ion transport +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "negative regulation of Rb+ transport" EXACT [GOC:obol] +synonym: "negative regulation of rubidium cation transport" EXACT [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-10T10:54:34Z + +[Term] +id: GO:2000682 +name: obsolete positive regulation of rubidium ion transport +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transport." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "positive regulation of Rb+ transport" EXACT [GOC:obol] +synonym: "positive regulation of rubidium cation transport" EXACT [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-10T10:54:37Z + +[Term] +id: GO:2000683 +name: regulation of cellular response to X-ray +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to X-ray." [GOC:obol] +synonym: "regulation of cellular response to X-ray radiation stimulus" EXACT [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +is_a: GO:0050794 ! regulation of cellular process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071481 ! cellular response to X-ray +relationship: regulates GO:0071481 ! cellular response to X-ray +created_by: yaf +creation_date: 2011-05-10T01:40:41Z + +[Term] +id: GO:2000684 +name: negative regulation of cellular response to X-ray +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray." [GOC:obol] +synonym: "negative regulation of cellular response to X-ray radiation stimulus" EXACT [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2000683 ! regulation of cellular response to X-ray +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071481 ! cellular response to X-ray +relationship: negatively_regulates GO:0071481 ! cellular response to X-ray +created_by: yaf +creation_date: 2011-05-10T01:40:45Z + +[Term] +id: GO:2000685 +name: positive regulation of cellular response to X-ray +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to X-ray." [GOC:obol] +synonym: "positive regulation of cellular response to X-ray radiation stimulus" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2000683 ! regulation of cellular response to X-ray +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071481 ! cellular response to X-ray +relationship: positively_regulates GO:0071481 ! cellular response to X-ray +created_by: yaf +creation_date: 2011-05-10T01:40:49Z + +[Term] +id: GO:2000686 +name: obsolete regulation of rubidium ion transmembrane transporter activity +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "regulation of Rb+ transmembrane transporter activity" EXACT [GOC:obol] +synonym: "regulation of rubidium cation transmembrane transporter activity" EXACT [GOC:obol] +synonym: "regulation of rubidium transmembrane transporter activity" RELATED [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-11T09:27:29Z + +[Term] +id: GO:2000687 +name: obsolete negative regulation of rubidium ion transmembrane transporter activity +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "negative regulation of Rb+ transmembrane transporter activity" EXACT [GOC:obol] +synonym: "negative regulation of rubidium cation transmembrane transporter activity" EXACT [GOC:obol] +synonym: "negative regulation of rubidium transmembrane transporter activity" RELATED [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-11T09:27:32Z + +[Term] +id: GO:2000688 +name: obsolete positive regulation of rubidium ion transmembrane transporter activity +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity." [GOC:yaf] +comment: This term has been obsoleted because it represents an assay, and not a physiological process. +synonym: "positive regulation of Rb+ transmembrane transporter activity" EXACT [GOC:obol] +synonym: "positive regulation of rubidium cation transmembrane transporter activity" EXACT [GOC:obol] +synonym: "positive regulation of rubidium transmembrane transporter activity" RELATED [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-05-11T09:27:33Z + +[Term] +id: GO:2000689 +name: actomyosin contractile ring assembly actin filament organization +namespace: biological_process +def: "An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis." [GOC:mah] +synonym: "actin filament organisation of constriction ring assembly" RELATED [GOC:obol] +synonym: "actin filament organisation of contractile ring assembly" EXACT [GOC:obol] +synonym: "actin filament organisation of cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:obol] +synonym: "actin filament organisation of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "actin filament organisation of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "actin filament organisation of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "actin filament organisation of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +synonym: "actin filament organization involved in cytokinetic actomyosin contractile ring assembly" EXACT [] +synonym: "actin filament organization of constriction ring assembly" RELATED [GOC:obol] +synonym: "actin filament organization of contractile ring assembly" EXACT [GOC:obol] +synonym: "actin filament organization of cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:obol] +synonym: "actin filament organization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "actin filament organization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "actin filament organization of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "actin filament organization of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of constriction ring assembly" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of contractile ring assembly" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "regulation of actin filament localization of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +is_a: GO:0007015 ! actin filament organization +is_a: GO:0022402 ! cell cycle process +intersection_of: GO:0007015 ! actin filament organization +intersection_of: part_of GO:0000915 ! actomyosin contractile ring assembly +relationship: part_of GO:0000915 ! actomyosin contractile ring assembly +created_by: mah +creation_date: 2011-05-17T11:48:12Z + +[Term] +id: GO:2000690 +name: regulation of cardiac muscle cell myoblast differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] +synonym: "regulation of cardiac myoblast differentiation" RELATED [GOC:obol] +synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] +is_a: GO:0045661 ! regulation of myoblast differentiation +is_a: GO:0051890 ! regulation of cardioblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +relationship: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +created_by: yaf +creation_date: 2011-05-25T09:08:01Z + +[Term] +id: GO:2000691 +name: negative regulation of cardiac muscle cell myoblast differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] +synonym: "negative regulation of cardiac myoblast differentiation" RELATED [GOC:obol] +synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] +is_a: GO:0045662 ! negative regulation of myoblast differentiation +is_a: GO:0051892 ! negative regulation of cardioblast differentiation +is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +relationship: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +created_by: yaf +creation_date: 2011-05-25T09:08:06Z + +[Term] +id: GO:2000692 +name: negative regulation of seed maturation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation." [GOC:obol] +is_a: GO:0048581 ! negative regulation of post-embryonic development +is_a: GO:2000034 ! regulation of seed maturation +is_a: GO:2000242 ! negative regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010431 ! seed maturation +relationship: negatively_regulates GO:0010431 ! seed maturation +created_by: dhl +creation_date: 2011-05-13T06:41:43Z + +[Term] +id: GO:2000693 +name: positive regulation of seed maturation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of seed maturation." [GOC:obol] +is_a: GO:0048582 ! positive regulation of post-embryonic development +is_a: GO:2000034 ! regulation of seed maturation +is_a: GO:2000243 ! positive regulation of reproductive process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010431 ! seed maturation +relationship: positively_regulates GO:0010431 ! seed maturation +created_by: dhl +creation_date: 2011-05-13T06:41:46Z + +[Term] +id: GO:2000694 +name: regulation of phragmoplast microtubule organization +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization." [GOC:obol] +synonym: "regulation of phragmoplast microtubule cytoskeleton organization" EXACT [GOC:obol] +synonym: "regulation of phragmoplast microtubule organisation" EXACT [GOC:mah] +is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0080175 ! phragmoplast microtubule organization +relationship: regulates GO:0080175 ! phragmoplast microtubule organization +created_by: tb +creation_date: 2011-05-13T09:32:27Z + +[Term] +id: GO:2000696 +name: regulation of epithelial cell differentiation involved in kidney development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] +is_a: GO:0030856 ! regulation of epithelial cell differentiation +is_a: GO:0090183 ! regulation of kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +relationship: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +created_by: bf +creation_date: 2011-05-16T04:23:52Z + +[Term] +id: GO:2000697 +name: negative regulation of epithelial cell differentiation involved in kidney development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] +is_a: GO:0030857 ! negative regulation of epithelial cell differentiation +is_a: GO:0090185 ! negative regulation of kidney development +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +relationship: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +created_by: bf +creation_date: 2011-05-16T04:23:55Z + +[Term] +id: GO:2000698 +name: positive regulation of epithelial cell differentiation involved in kidney development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] +is_a: GO:0030858 ! positive regulation of epithelial cell differentiation +is_a: GO:0090184 ! positive regulation of kidney development +is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +relationship: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development +created_by: bf +creation_date: 2011-05-16T04:23:57Z + +[Term] +id: GO:2000699 +name: fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10, GOC:yaf] +synonym: "FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: GO:0008543 ! fibroblast growth factor receptor signaling pathway +intersection_of: part_of GO:0060676 ! ureteric bud formation +relationship: part_of GO:0060676 ! ureteric bud formation +created_by: bf +creation_date: 2011-05-16T04:52:14Z + +[Term] +id: GO:2000700 +name: positive regulation of cardiac muscle cell myoblast differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] +synonym: "positive regulation of cardiac myoblast differentiation" RELATED [GOC:obol] +synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] +is_a: GO:0045663 ! positive regulation of myoblast differentiation +is_a: GO:0051891 ! positive regulation of cardioblast differentiation +is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +relationship: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation +created_by: yaf +creation_date: 2011-05-25T09:08:09Z + +[Term] +id: GO:2000701 +name: glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0035860 ! glial cell-derived neurotrophic factor receptor signaling pathway +intersection_of: GO:0035860 ! glial cell-derived neurotrophic factor receptor signaling pathway +intersection_of: part_of GO:0060676 ! ureteric bud formation +relationship: part_of GO:0060676 ! ureteric bud formation +created_by: yaf +creation_date: 2011-05-25T09:34:07Z + +[Term] +id: GO:2000702 +name: regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0040036 ! regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0072106 ! regulation of ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +relationship: regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-05-25T09:48:15Z + +[Term] +id: GO:2000703 +name: negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "negative regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0040037 ! negative regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905277 ! negative regulation of epithelial tube formation +is_a: GO:2000702 ! regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +relationship: negatively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-05-25T09:48:22Z + +[Term] +id: GO:2000704 +name: positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "positive regulation of FGF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of FGF receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of FGFR signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0045743 ! positive regulation of fibroblast growth factor receptor signaling pathway +is_a: GO:0072107 ! positive regulation of ureteric bud formation +is_a: GO:2000702 ! regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +relationship: positively_regulates GO:2000699 ! fibroblast growth factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-05-25T09:48:27Z + +[Term] +id: GO:2000705 +name: regulation of dense core granule biogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dense core granule biogenesis." [GOC:obol] +is_a: GO:0044087 ! regulation of cellular component biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0061110 ! dense core granule biogenesis +relationship: regulates GO:0061110 ! dense core granule biogenesis +created_by: yaf +creation_date: 2011-05-26T10:29:21Z + +[Term] +id: GO:2000706 +name: negative regulation of dense core granule biogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis." [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:2000705 ! regulation of dense core granule biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061110 ! dense core granule biogenesis +relationship: negatively_regulates GO:0061110 ! dense core granule biogenesis +created_by: yaf +creation_date: 2011-05-26T10:29:27Z + +[Term] +id: GO:2000707 +name: positive regulation of dense core granule biogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis." [GOC:obol] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:2000705 ! regulation of dense core granule biogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0061110 ! dense core granule biogenesis +relationship: positively_regulates GO:0061110 ! dense core granule biogenesis +created_by: yaf +creation_date: 2011-05-26T10:29:30Z + +[Term] +id: GO:2000708 +name: myosin filament organization involved in cytokinetic actomyosin contractile ring assembly +namespace: biological_process +def: "A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis." [GOC:mah] +synonym: "myosin filament assembly or disassembly of constriction ring assembly" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "myosin filament assembly or disassembly of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly" EXACT [GOC:mah] +synonym: "myosin filament organization of constriction ring assembly" RELATED [GOC:obol] +synonym: "myosin filament organization of contractile ring assembly" EXACT [GOC:obol] +synonym: "myosin filament organization of cytokinesis, actomyosin contractile ring assembly" EXACT [GOC:obol] +synonym: "myosin filament organization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "myosin filament organization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "myosin filament organization of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "myosin filament organization of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of constriction ring assembly" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring assembly" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring formation" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of cytokinesis, actomyosin ring biosynthesis" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of cytokinesis, actomyosin ring formation" RELATED [GOC:obol] +synonym: "myosin polymerization or depolymerization of cytokinesis, contractile ring assembly" RELATED [GOC:obol] +is_a: GO:0022402 ! cell cycle process +is_a: GO:0031033 ! myosin filament organization +intersection_of: GO:0031033 ! myosin filament organization +intersection_of: part_of GO:0000915 ! actomyosin contractile ring assembly +relationship: part_of GO:0000915 ! actomyosin contractile ring assembly +created_by: mah +creation_date: 2011-06-01T12:33:56Z + +[Term] +id: GO:2000709 +name: regulation of maintenance of meiotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "regulation of maintenance of centromeric meiotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "regulation of maintenance of meiotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "regulation of maintenance of sister chromatin cohesion at centromere at meiosis I" EXACT [GOC:obol] +is_a: GO:0034094 ! regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:0070602 ! regulation of centromeric sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +relationship: regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-01T12:41:11Z + +[Term] +id: GO:2000710 +name: negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "negative regulation of maintenance of centromeric meiotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of meiotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of sister chromatin cohesion at centromere at meiosis I" EXACT [GOC:obol] +is_a: GO:0034095 ! negative regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:2000709 ! regulation of maintenance of meiotic sister chromatid cohesion, centromeric +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +relationship: negatively_regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-01T12:41:16Z + +[Term] +id: GO:2000711 +name: positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "positive regulation of maintenance of centromeric meiotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of meiotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of sister chromatin cohesion at centromere at meiosis I" EXACT [GOC:obol] +is_a: GO:0034096 ! positive regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:2000709 ! regulation of maintenance of meiotic sister chromatid cohesion, centromeric +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +relationship: positively_regulates GO:0035875 ! maintenance of meiotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-01T12:41:18Z + +[Term] +id: GO:2000712 +name: regulation of maintenance of meiotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "regulation of maintenance of meiotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "regulation of maintenance of sister chromatin cohesion along arms at meiosis I" EXACT [GOC:obol] +is_a: GO:0034094 ! regulation of maintenance of meiotic sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +relationship: regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-01T12:45:35Z + +[Term] +id: GO:2000713 +name: negative regulation of maintenance of meiotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "negative regulation of maintenance of meiotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of sister chromatin cohesion along arms at meiosis I" EXACT [GOC:obol] +is_a: GO:0034095 ! negative regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:2000712 ! regulation of maintenance of meiotic sister chromatid cohesion, arms +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +relationship: negatively_regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-01T12:45:39Z + +[Term] +id: GO:2000714 +name: positive regulation of maintenance of meiotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "positive regulation of maintenance of meiotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of sister chromatin cohesion along arms at meiosis I" EXACT [GOC:obol] +is_a: GO:0034096 ! positive regulation of maintenance of meiotic sister chromatid cohesion +is_a: GO:2000712 ! regulation of maintenance of meiotic sister chromatid cohesion, arms +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +relationship: positively_regulates GO:0035876 ! maintenance of meiotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-01T12:45:42Z + +[Term] +id: GO:2000715 +name: regulation of maintenance of mitotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "regulation of maintenance of mitotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "regulation of maintenance of sister chromatin cohesion along arms at mitosis" EXACT [GOC:obol] +is_a: GO:0034182 ! regulation of maintenance of mitotic sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +relationship: regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-03T10:38:29Z + +[Term] +id: GO:2000716 +name: negative regulation of maintenance of mitotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "negative regulation of maintenance of mitotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of sister chromatin cohesion along arms at mitosis" EXACT [GOC:obol] +is_a: GO:0034183 ! negative regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:2000715 ! regulation of maintenance of mitotic sister chromatid cohesion, arms +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +relationship: negatively_regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-03T10:38:32Z + +[Term] +id: GO:2000717 +name: positive regulation of maintenance of mitotic sister chromatid cohesion, arms +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms." [GOC:mah] +synonym: "positive regulation of maintenance of mitotic sister chromatin cohesion along arms" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of sister chromatin cohesion along arms at mitosis" EXACT [GOC:obol] +is_a: GO:0034184 ! positive regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:2000715 ! regulation of maintenance of mitotic sister chromatid cohesion, arms +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +relationship: positively_regulates GO:0071959 ! maintenance of mitotic sister chromatid cohesion, arms +created_by: mah +creation_date: 2011-06-03T10:38:35Z + +[Term] +id: GO:2000718 +name: regulation of maintenance of mitotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "regulation of maintenance of centromeric mitotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "regulation of maintenance of mitotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "regulation of maintenance of sister chromatin cohesion at centromere at mitosis" EXACT [GOC:obol] +is_a: GO:0034182 ! regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:0070602 ! regulation of centromeric sister chromatid cohesion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +relationship: regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-03T10:41:11Z + +[Term] +id: GO:2000719 +name: negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "negative regulation of maintenance of centromeric mitotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of mitotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "negative regulation of maintenance of sister chromatin cohesion at centromere at mitosis" EXACT [GOC:obol] +is_a: GO:0034183 ! negative regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:2000718 ! regulation of maintenance of mitotic sister chromatid cohesion, centromeric +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +relationship: negatively_regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-03T10:41:14Z + +[Term] +id: GO:2000720 +name: positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region." [GOC:mah] +synonym: "positive regulation of maintenance of centromeric mitotic sister chromatin cohesion" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of mitotic sister chromatin cohesion at centromere" EXACT [GOC:obol] +synonym: "positive regulation of maintenance of sister chromatin cohesion at centromere at mitosis" EXACT [GOC:obol] +is_a: GO:0034184 ! positive regulation of maintenance of mitotic sister chromatid cohesion +is_a: GO:2000718 ! regulation of maintenance of mitotic sister chromatid cohesion, centromeric +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +relationship: positively_regulates GO:0071960 ! maintenance of mitotic sister chromatid cohesion, centromeric +created_by: mah +creation_date: 2011-06-03T10:41:16Z + +[Term] +id: GO:2000721 +name: positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation." [GOC:BHF] +synonym: "activation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "activation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "activation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "activation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of gene-specific transcription from RNA polymerase II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of global transcription from Pol II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of global transcription from Pol II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase II promoter, global of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "stimulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "stimulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "stimulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "stimulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "up regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "up regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "up regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "up regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "up-regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "up-regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "up-regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "upregulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "upregulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0051145 ! smooth muscle cell differentiation +relationship: part_of GO:0051145 ! smooth muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T08:34:55Z + +[Term] +id: GO:2000722 +name: regulation of cardiac vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation." [GOC:BHF] +synonym: "regulation of heart vascular smooth muscle cell differentiation" EXACT [GOC:obol] +is_a: GO:1905063 ! regulation of vascular smooth muscle cell differentiation +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +relationship: regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T08:47:58Z + +[Term] +id: GO:2000723 +name: negative regulation of cardiac vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation." [GOC:BHF] +synonym: "negative regulation of heart vascular smooth muscle cell differentiation" EXACT [GOC:obol] +is_a: GO:1905064 ! negative regulation of vascular smooth muscle cell differentiation +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +is_a: GO:2000722 ! regulation of cardiac vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +relationship: negatively_regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T08:48:01Z + +[Term] +id: GO:2000724 +name: positive regulation of cardiac vascular smooth muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation." [GOC:BHF] +synonym: "positive regulation of heart vascular smooth muscle cell differentiation" EXACT [GOC:obol] +is_a: GO:1905065 ! positive regulation of vascular smooth muscle cell differentiation +is_a: GO:1905209 ! positive regulation of cardiocyte differentiation +is_a: GO:2000722 ! regulation of cardiac vascular smooth muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +relationship: positively_regulates GO:0060947 ! cardiac vascular smooth muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T08:48:04Z + +[Term] +id: GO:2000725 +name: regulation of cardiac muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] +synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol] +synonym: "regulation of heart muscle cell differentiation" RELATED [GOC:obol] +is_a: GO:0051153 ! regulation of striated muscle cell differentiation +is_a: GO:0055024 ! regulation of cardiac muscle tissue development +is_a: GO:1905207 ! regulation of cardiocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0055007 ! cardiac muscle cell differentiation +relationship: regulates GO:0055007 ! cardiac muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T10:51:06Z + +[Term] +id: GO:2000726 +name: negative regulation of cardiac muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] +synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol] +synonym: "negative regulation of heart muscle cell differentiation" RELATED [GOC:obol] +is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation +is_a: GO:0055026 ! negative regulation of cardiac muscle tissue development +is_a: GO:1905208 ! negative regulation of cardiocyte differentiation +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation +relationship: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T10:51:11Z + +[Term] +id: GO:2000727 +name: positive regulation of cardiac muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] +synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol] +synonym: "positive regulation of heart muscle cell differentiation" RELATED [GOC:obol] +is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation +is_a: GO:0055025 ! positive regulation of cardiac muscle tissue development +is_a: GO:1905209 ! positive regulation of cardiocyte differentiation +is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0055007 ! cardiac muscle cell differentiation +relationship: positively_regulates GO:0055007 ! cardiac muscle cell differentiation +created_by: vk +creation_date: 2011-06-08T10:51:15Z + +[Term] +id: GO:2000728 +name: regulation of mRNA export from nucleus in response to heat stress +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress." [PMID:15210706] +synonym: "regulation of mRNA export from cell nucleus during heat stress" EXACT [GOC:obol] +synonym: "regulation of mRNA export from nucleus during heat stress" RELATED [GOC:obol] +is_a: GO:0010793 ! regulation of mRNA export from nucleus +is_a: GO:1900034 ! regulation of cellular response to heat +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0031990 ! mRNA export from nucleus in response to heat stress +relationship: regulates GO:0031990 ! mRNA export from nucleus in response to heat stress +created_by: pr +creation_date: 2011-06-08T12:17:45Z + +[Term] +id: GO:2000729 +name: positive regulation of mesenchymal cell proliferation involved in ureter development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol] +synonym: "positive regulation of ureter mesenchymal cell proliferation" RELATED [GOC:obol] +synonym: "positive regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:obol] +is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +relationship: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development +created_by: yaf +creation_date: 2011-06-10T02:27:19Z + +[Term] +id: GO:2000730 +name: regulation of termination of RNA polymerase I transcription +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription." [GOC:obol] +synonym: "regulation of RNA polymerase I transcription termination" EXACT [GOC:obol] +synonym: "regulation of transcription termination from Pol I promoter" EXACT [GOC:obol] +synonym: "regulation of transcription termination from RNA polymerase I promoter" EXACT [GOC:obol] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +is_a: GO:0031554 ! regulation of DNA-templated transcription, termination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006363 ! termination of RNA polymerase I transcription +relationship: regulates GO:0006363 ! termination of RNA polymerase I transcription +created_by: dph +creation_date: 2011-06-10T08:43:39Z + +[Term] +id: GO:2000731 +name: negative regulation of termination of RNA polymerase I transcription +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription." [GOC:obol] +synonym: "negative regulation of RNA polymerase I transcription termination" EXACT [GOC:obol] +synonym: "negative regulation of transcription termination from Pol I promoter" EXACT [GOC:obol] +synonym: "negative regulation of transcription termination from RNA polymerase I promoter" EXACT [GOC:obol] +is_a: GO:0016479 ! negative regulation of transcription by RNA polymerase I +is_a: GO:0060567 ! negative regulation of DNA-templated transcription, termination +is_a: GO:2000730 ! regulation of termination of RNA polymerase I transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006363 ! termination of RNA polymerase I transcription +relationship: negatively_regulates GO:0006363 ! termination of RNA polymerase I transcription +created_by: dph +creation_date: 2011-06-10T08:43:44Z + +[Term] +id: GO:2000732 +name: positive regulation of termination of RNA polymerase I transcription +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription." [GOC:obol] +synonym: "positive regulation of RNA polymerase I transcription termination" EXACT [GOC:obol] +synonym: "positive regulation of transcription termination from Pol I promoter" EXACT [GOC:obol] +synonym: "positive regulation of transcription termination from RNA polymerase I promoter" EXACT [GOC:obol] +is_a: GO:0045943 ! positive regulation of transcription by RNA polymerase I +is_a: GO:0060566 ! positive regulation of DNA-templated transcription, termination +is_a: GO:2000730 ! regulation of termination of RNA polymerase I transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006363 ! termination of RNA polymerase I transcription +relationship: positively_regulates GO:0006363 ! termination of RNA polymerase I transcription +created_by: dph +creation_date: 2011-06-10T08:43:48Z + +[Term] +id: GO:2000733 +name: regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol] +synonym: "regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0072106 ! regulation of ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +relationship: regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-06-13T11:14:40Z + +[Term] +id: GO:2000734 +name: negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol] +synonym: "negative regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0045992 ! negative regulation of embryonic development +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:1905277 ! negative regulation of epithelial tube formation +is_a: GO:2000733 ! regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +relationship: negatively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-06-13T11:14:44Z + +[Term] +id: GO:2000735 +name: positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation." [GOC:obol] +synonym: "positive regulation of GDNF receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation" EXACT [GOC:obol] +synonym: "positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation" EXACT [GOC:obol] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0072107 ! positive regulation of ureteric bud formation +is_a: GO:2000733 ! regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +relationship: positively_regulates GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +created_by: yaf +creation_date: 2011-06-13T11:14:46Z + +[Term] +id: GO:2000736 +name: regulation of stem cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol] +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0048863 ! stem cell differentiation +relationship: regulates GO:0048863 ! stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:05:16Z + +[Term] +id: GO:2000737 +name: negative regulation of stem cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0048863 ! stem cell differentiation +relationship: negatively_regulates GO:0048863 ! stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:05:20Z + +[Term] +id: GO:2000738 +name: positive regulation of stem cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0048863 ! stem cell differentiation +relationship: positively_regulates GO:0048863 ! stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:05:23Z + +[Term] +id: GO:2000739 +name: regulation of mesenchymal stem cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation." [GOC:obol] +is_a: GO:2000736 ! regulation of stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072497 ! mesenchymal stem cell differentiation +relationship: regulates GO:0072497 ! mesenchymal stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:31:27Z + +[Term] +id: GO:2000740 +name: negative regulation of mesenchymal stem cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation." [GOC:obol] +is_a: GO:2000737 ! negative regulation of stem cell differentiation +is_a: GO:2000739 ! regulation of mesenchymal stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072497 ! mesenchymal stem cell differentiation +relationship: negatively_regulates GO:0072497 ! mesenchymal stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:31:31Z + +[Term] +id: GO:2000741 +name: positive regulation of mesenchymal stem cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation." [GOC:obol] +is_a: GO:2000738 ! positive regulation of stem cell differentiation +is_a: GO:2000739 ! regulation of mesenchymal stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072497 ! mesenchymal stem cell differentiation +relationship: positively_regulates GO:0072497 ! mesenchymal stem cell differentiation +created_by: yaf +creation_date: 2011-06-14T02:31:34Z + +[Term] +id: GO:2000742 +name: regulation of anterior head development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of anterior head development." [GOC:obol] +is_a: GO:0050793 ! regulation of developmental process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097065 ! anterior head development +relationship: regulates GO:0097065 ! anterior head development +created_by: yaf +creation_date: 2011-06-14T09:44:09Z + +[Term] +id: GO:2000743 +name: negative regulation of anterior head development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development." [GOC:obol] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:2000742 ! regulation of anterior head development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097065 ! anterior head development +relationship: negatively_regulates GO:0097065 ! anterior head development +created_by: yaf +creation_date: 2011-06-14T09:44:14Z + +[Term] +id: GO:2000744 +name: positive regulation of anterior head development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of anterior head development." [GOC:obol] +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:2000742 ! regulation of anterior head development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097065 ! anterior head development +relationship: positively_regulates GO:0097065 ! anterior head development +created_by: yaf +creation_date: 2011-06-14T09:44:17Z + +[Term] +id: GO:2000745 +name: obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation +namespace: biological_process +def: "OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation." [GOC:BHF] +comment: This term was made obsolete because it was added in error. +synonym: "activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation" EXACT [] +synonym: "positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation" EXACT [GOC:obol] +is_obsolete: true +created_by: bf +creation_date: 2011-06-15T10:03:19Z + +[Term] +id: GO:2000746 +name: regulation of defecation rhythm +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of defecation rhythm." [GOC:kmv] +synonym: "regulation of defecation behavior" RELATED [GOC:obol] +synonym: "regulation of defecation cycle" EXACT [GOC:obol] +synonym: "regulation of defecation motor program" EXACT [GOC:obol] +synonym: "regulation of DMP" EXACT [GOC:obol] +is_a: GO:2000292 ! regulation of defecation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035882 ! defecation rhythm +relationship: regulates GO:0035882 ! defecation rhythm +created_by: bf +creation_date: 2011-06-15T03:23:07Z + +[Term] +id: GO:2000747 +name: negative regulation of defecation rhythm +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm." [GOC:kmv] +synonym: "negative regulation of defecation behavior" RELATED [GOC:obol] +synonym: "negative regulation of defecation cycle" EXACT [GOC:obol] +synonym: "negative regulation of defecation motor program" EXACT [GOC:obol] +synonym: "negative regulation of DMP" EXACT [GOC:obol] +is_a: GO:2000293 ! negative regulation of defecation +is_a: GO:2000746 ! regulation of defecation rhythm +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035882 ! defecation rhythm +relationship: negatively_regulates GO:0035882 ! defecation rhythm +created_by: bf +creation_date: 2011-06-15T03:23:10Z + +[Term] +id: GO:2000748 +name: positive regulation of defecation rhythm +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of defecation rhythm." [GOC:kmv] +synonym: "positive regulation of defecation behavior" RELATED [GOC:obol] +synonym: "positive regulation of defecation cycle" EXACT [GOC:obol] +synonym: "positive regulation of defecation motor program" EXACT [GOC:obol] +synonym: "positive regulation of DMP" EXACT [GOC:obol] +is_a: GO:2000294 ! positive regulation of defecation +is_a: GO:2000746 ! regulation of defecation rhythm +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035882 ! defecation rhythm +relationship: positively_regulates GO:0035882 ! defecation rhythm +created_by: bf +creation_date: 2011-06-15T03:23:13Z + +[Term] +id: GO:2000749 +name: positive regulation of rDNA heterochromatin assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of assembly of rDNA heterochromatin." [PMID:10899127] +synonym: "positive regulation of chromatin silencing at rDNA" BROAD [] +synonym: "positive regulation of chromatin silencing at ribosomal DNA" BROAD [GOC:obol] +synonym: "positive regulation of heterochromatic silencing at rDNA" BROAD [GOC:obol] +synonym: "positive regulation of rDNA chromatin silencing" BROAD [GOC:obol] +synonym: "positive regulation of ribosomal DNA heterochromatin assembly" EXACT [] +is_a: GO:0031453 ! positive regulation of heterochromatin assembly +is_a: GO:0061187 ! regulation of ribosomal DNA heterochromatin assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000183 ! rDNA heterochromatin assembly +relationship: positively_regulates GO:0000183 ! rDNA heterochromatin assembly +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/19238 xsd:anyURI +created_by: pr +creation_date: 2011-06-16T09:43:55Z + +[Term] +id: GO:2000750 +name: negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape." [GOC:mah] +is_a: GO:2000100 ! regulation of establishment or maintenance of bipolar cell polarity regulating cell shape +is_a: GO:2000770 ! negative regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +relationship: negatively_regulates GO:0061246 ! establishment or maintenance of bipolar cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-16T11:51:49Z + +[Term] +id: GO:2000751 +name: histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore +namespace: biological_process +def: "Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore." [GOC:obol] +synonym: "histone H3-T3 phosphorylation of chromosomal passenger complex localization to kinetochore" EXACT [GOC:obol] +synonym: "histone H3-T3 phosphorylation of chromosome passenger complex localisation to kinetochore" RELATED [GOC:obol] +synonym: "histone H3-T3 phosphorylation of chromosome passenger complex localization to kinetochore" EXACT [GOC:obol] +synonym: "histone H3-T3 phosphorylation of CPC complex localization to kinetochore" EXACT [GOC:obol] +synonym: "histone H3-T3 phosphorylation of CPC localization to kinetochore" EXACT [GOC:obol] +is_a: GO:0072355 ! histone H3-T3 phosphorylation +intersection_of: GO:0072355 ! histone H3-T3 phosphorylation +intersection_of: part_of GO:0072356 ! chromosome passenger complex localization to kinetochore +relationship: part_of GO:0072356 ! chromosome passenger complex localization to kinetochore +created_by: vw +creation_date: 2011-06-16T12:56:29Z + +[Term] +id: GO:2000752 +name: regulation of glucosylceramide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process." [GOC:BHF] +synonym: "regulation of glucosylceramide breakdown" EXACT [GOC:obol] +synonym: "regulation of glucosylceramide catabolism" EXACT [GOC:obol] +synonym: "regulation of glucosylceramide degradation" EXACT [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0050994 ! regulation of lipid catabolic process +is_a: GO:1905038 ! regulation of membrane lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006680 ! glucosylceramide catabolic process +relationship: regulates GO:0006680 ! glucosylceramide catabolic process +created_by: rl +creation_date: 2011-06-16T03:12:04Z + +[Term] +id: GO:2000753 +name: positive regulation of glucosylceramide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process." [GOC:BHF] +synonym: "positive regulation of glucosylceramide breakdown" EXACT [GOC:obol] +synonym: "positive regulation of glucosylceramide catabolism" EXACT [GOC:obol] +synonym: "positive regulation of glucosylceramide degradation" EXACT [GOC:obol] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0050996 ! positive regulation of lipid catabolic process +is_a: GO:2000752 ! regulation of glucosylceramide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006680 ! glucosylceramide catabolic process +relationship: positively_regulates GO:0006680 ! glucosylceramide catabolic process +created_by: rl +creation_date: 2011-06-16T03:12:09Z + +[Term] +id: GO:2000754 +name: regulation of sphingomyelin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process." [GOC:BHF] +synonym: "regulation of sphingomyelin breakdown" EXACT [GOC:obol] +synonym: "regulation of sphingomyelin catabolism" EXACT [GOC:obol] +synonym: "regulation of sphingomyelin degradation" EXACT [GOC:obol] +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0060696 ! regulation of phospholipid catabolic process +is_a: GO:1905038 ! regulation of membrane lipid metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006685 ! sphingomyelin catabolic process +relationship: regulates GO:0006685 ! sphingomyelin catabolic process +created_by: rl +creation_date: 2011-06-16T03:17:30Z + +[Term] +id: GO:2000755 +name: positive regulation of sphingomyelin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process." [GOC:BHF] +synonym: "positive regulation of sphingomyelin breakdown" EXACT [GOC:obol] +synonym: "positive regulation of sphingomyelin catabolism" EXACT [GOC:obol] +synonym: "positive regulation of sphingomyelin degradation" EXACT [GOC:obol] +is_a: GO:0034250 ! positive regulation of cellular amide metabolic process +is_a: GO:0060697 ! positive regulation of phospholipid catabolic process +is_a: GO:2000754 ! regulation of sphingomyelin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006685 ! sphingomyelin catabolic process +relationship: positively_regulates GO:0006685 ! sphingomyelin catabolic process +created_by: rl +creation_date: 2011-06-16T03:17:35Z + +[Term] +id: GO:2000756 +name: regulation of peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1901983 ! regulation of protein acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018394 ! peptidyl-lysine acetylation +relationship: regulates GO:0018394 ! peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-16T09:51:26Z + +[Term] +id: GO:2000757 +name: negative regulation of peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1901984 ! negative regulation of protein acetylation +is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018394 ! peptidyl-lysine acetylation +relationship: negatively_regulates GO:0018394 ! peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-16T09:51:31Z + +[Term] +id: GO:2000758 +name: positive regulation of peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1901985 ! positive regulation of protein acetylation +is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018394 ! peptidyl-lysine acetylation +relationship: positively_regulates GO:0018394 ! peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-16T09:51:35Z + +[Term] +id: GO:2000759 +name: regulation of N-terminal peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1903317 ! regulation of protein maturation +is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +relationship: regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-17T12:58:16Z + +[Term] +id: GO:2000760 +name: negative regulation of N-terminal peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1903318 ! negative regulation of protein maturation +is_a: GO:2000757 ! negative regulation of peptidyl-lysine acetylation +is_a: GO:2000759 ! regulation of N-terminal peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +relationship: negatively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-17T12:58:20Z + +[Term] +id: GO:2000761 +name: positive regulation of N-terminal peptidyl-lysine acetylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] +is_a: GO:1903319 ! positive regulation of protein maturation +is_a: GO:2000758 ! positive regulation of peptidyl-lysine acetylation +is_a: GO:2000759 ! regulation of N-terminal peptidyl-lysine acetylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +relationship: positively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation +created_by: yaf +creation_date: 2011-06-17T12:58:24Z + +[Term] +id: GO:2000762 +name: regulation of phenylpropanoid metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process." [GOC:obol] +synonym: "regulation of phenylpropanoid metabolism" EXACT [GOC:obol] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0043455 ! regulation of secondary metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009698 ! phenylpropanoid metabolic process +relationship: regulates GO:0009698 ! phenylpropanoid metabolic process +created_by: tb +creation_date: 2011-06-17T06:13:43Z + +[Term] +id: GO:2000763 +name: positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process +namespace: biological_process +def: "Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process." [GOC:BHF] +synonym: "positive regulation of transcription from Pol II promoter involved in levarterenol biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in levarterenol biosynthetic process" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthetic process" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in norepinephrine anabolism" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthetic process" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in norepinephrine formation" EXACT [GOC:obol] +synonym: "positive regulation of transcription from Pol II promoter involved in norepinephrine synthesis" EXACT [GOC:obol] +is_a: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: GO:0045944 ! positive regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0042421 ! norepinephrine biosynthetic process +relationship: part_of GO:0042421 ! norepinephrine biosynthetic process +created_by: vk +creation_date: 2011-06-18T04:14:58Z + +[Term] +id: GO:2000764 +name: positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis." [GOC:BHF] +synonym: "positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis" EXACT [GOC:obol] +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2000826 ! regulation of heart morphogenesis +is_a: GO:2001262 ! positive regulation of semaphorin-plexin signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071527 ! semaphorin-plexin signaling pathway involved in outflow tract morphogenesis +relationship: positively_regulates GO:0071527 ! semaphorin-plexin signaling pathway involved in outflow tract morphogenesis +created_by: vk +creation_date: 2011-06-18T04:26:00Z + +[Term] +id: GO:2000765 +name: regulation of cytoplasmic translation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cytoplasmic translation." [GOC:obol] +is_a: GO:0006417 ! regulation of translation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002181 ! cytoplasmic translation +relationship: regulates GO:0002181 ! cytoplasmic translation +created_by: vw +creation_date: 2011-06-20T10:39:19Z + +[Term] +id: GO:2000766 +name: negative regulation of cytoplasmic translation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation." [GOC:obol] +is_a: GO:0017148 ! negative regulation of translation +is_a: GO:2000765 ! regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002181 ! cytoplasmic translation +relationship: negatively_regulates GO:0002181 ! cytoplasmic translation +created_by: vw +creation_date: 2011-06-20T10:39:23Z + +[Term] +id: GO:2000767 +name: positive regulation of cytoplasmic translation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation." [GOC:obol] +is_a: GO:0045727 ! positive regulation of translation +is_a: GO:2000765 ! regulation of cytoplasmic translation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002181 ! cytoplasmic translation +relationship: positively_regulates GO:0002181 ! cytoplasmic translation +created_by: vw +creation_date: 2011-06-20T10:39:26Z + +[Term] +id: GO:2000768 +name: positive regulation of nephron tubule epithelial cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol] +is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation +is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation +relationship: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation +created_by: yaf +creation_date: 2011-06-22T11:55:06Z + +[Term] +id: GO:2000769 +name: regulation of establishment or maintenance of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape." [GOC:mah] +is_a: GO:0008360 ! regulation of cell shape +is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +relationship: regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-22T01:56:49Z + +[Term] +id: GO:2000770 +name: negative regulation of establishment or maintenance of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape." [GOC:mah] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:2000769 ! regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +relationship: negatively_regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-22T01:56:53Z + +[Term] +id: GO:2000771 +name: positive regulation of establishment or maintenance of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape." [GOC:mah] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:2000769 ! regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +relationship: positively_regulates GO:0071963 ! establishment or maintenance of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-22T01:56:55Z + +[Term] +id: GO:2000772 +name: regulation of cellular senescence +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular senescence." [GOC:BHF] +is_a: GO:0080135 ! regulation of cellular response to stress +is_a: GO:0090342 ! regulation of cell aging +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0090398 ! cellular senescence +relationship: regulates GO:0090398 ! cellular senescence +created_by: bf +creation_date: 2011-06-22T01:57:04Z + +[Term] +id: GO:2000773 +name: negative regulation of cellular senescence +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence." [GOC:BHF] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:0090344 ! negative regulation of cell aging +is_a: GO:2000772 ! regulation of cellular senescence +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0090398 ! cellular senescence +relationship: negatively_regulates GO:0090398 ! cellular senescence +created_by: bf +creation_date: 2011-06-22T01:57:08Z + +[Term] +id: GO:2000774 +name: positive regulation of cellular senescence +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular senescence." [GOC:BHF] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:0090343 ! positive regulation of cell aging +is_a: GO:2000772 ! regulation of cellular senescence +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0090398 ! cellular senescence +relationship: positively_regulates GO:0090398 ! cellular senescence +created_by: bf +creation_date: 2011-06-22T01:57:12Z + +[Term] +id: GO:2000775 +name: histone H3-S10 phosphorylation involved in chromosome condensation +namespace: biological_process +def: "Any histone H3-S10 phosphorylation that is involved in chromosome condensation." [GOC:obol] +synonym: "histone H3 phosphorylation at S10 of chromosome condensation" EXACT [GOC:obol] +synonym: "histone H3-S10 phosphorylation of chromosome condensation" EXACT [GOC:obol] +synonym: "histone H3S10 phosphorylation of chromosome condensation" EXACT [GOC:obol] +is_a: GO:0043987 ! histone H3-S10 phosphorylation +intersection_of: GO:0043987 ! histone H3-S10 phosphorylation +intersection_of: part_of GO:0030261 ! chromosome condensation +relationship: part_of GO:0030261 ! chromosome condensation +created_by: mah +creation_date: 2011-06-22T03:58:00Z + +[Term] +id: GO:2000776 +name: histone H4 acetylation involved in response to DNA damage stimulus +namespace: biological_process +def: "Any histone H4 acetylation that is involved in a response to DNA damage stimulus." [GOC:mah] +synonym: "histone H4 acetylation of cellular DNA damage response" EXACT [GOC:obol] +synonym: "histone H4 acetylation of cellular response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "histone H4 acetylation of DNA damage response" EXACT [GOC:obol] +synonym: "histone H4 acetylation of response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "histone H4 acetylation of response to genotoxic stress" EXACT [GOC:obol] +is_a: GO:0043967 ! histone H4 acetylation +intersection_of: GO:0043967 ! histone H4 acetylation +intersection_of: part_of GO:0006974 ! cellular response to DNA damage stimulus +relationship: part_of GO:0006974 ! cellular response to DNA damage stimulus +created_by: mah +creation_date: 2011-06-22T04:00:54Z + +[Term] +id: GO:2000777 +name: positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia +namespace: biological_process +def: "Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia." [GOC:mah] +synonym: "positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxic stress" EXACT [GOC:obol] +synonym: "positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to lowered oxygen tension" EXACT [GOC:obol] +is_a: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +intersection_of: GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process +intersection_of: part_of GO:0071456 ! cellular response to hypoxia +relationship: part_of GO:0071456 ! cellular response to hypoxia +created_by: mah +creation_date: 2011-06-22T04:07:20Z + +[Term] +id: GO:2000778 +name: positive regulation of interleukin-6 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion." [GOC:BHF] +synonym: "positive regulation of IL-6 secretion" EXACT [GOC:obol] +is_a: GO:0032755 ! positive regulation of interleukin-6 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072604 ! interleukin-6 secretion +relationship: positively_regulates GO:0072604 ! interleukin-6 secretion +created_by: vk +creation_date: 2011-06-22T08:27:45Z + +[Term] +id: GO:2000779 +name: regulation of double-strand break repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of double-strand break repair." [GOC:BHF] +is_a: GO:0006282 ! regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006302 ! double-strand break repair +relationship: regulates GO:0006302 ! double-strand break repair +created_by: bf +creation_date: 2011-06-23T09:28:02Z + +[Term] +id: GO:2000780 +name: negative regulation of double-strand break repair +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair." [GOC:BHF] +is_a: GO:0045738 ! negative regulation of DNA repair +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006302 ! double-strand break repair +relationship: negatively_regulates GO:0006302 ! double-strand break repair +created_by: bf +creation_date: 2011-06-23T09:28:08Z + +[Term] +id: GO:2000781 +name: positive regulation of double-strand break repair +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of double-strand break repair." [GOC:BHF] +is_a: GO:0045739 ! positive regulation of DNA repair +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006302 ! double-strand break repair +relationship: positively_regulates GO:0006302 ! double-strand break repair +created_by: bf +creation_date: 2011-06-23T09:28:13Z + +[Term] +id: GO:2000782 +name: regulation of establishment of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape." [GOC:Mah] +is_a: GO:2000114 ! regulation of establishment of cell polarity +is_a: GO:2000769 ! regulation of establishment or maintenance of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071964 ! establishment of cell polarity regulating cell shape +relationship: regulates GO:0071964 ! establishment of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-23T12:17:38Z + +[Term] +id: GO:2000783 +name: negative regulation of establishment of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape." [GOC:Mah] +is_a: GO:2000770 ! negative regulation of establishment or maintenance of cell polarity regulating cell shape +is_a: GO:2000782 ! regulation of establishment of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071964 ! establishment of cell polarity regulating cell shape +relationship: negatively_regulates GO:0071964 ! establishment of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-23T12:17:44Z + +[Term] +id: GO:2000784 +name: positive regulation of establishment of cell polarity regulating cell shape +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape." [GOC:Mah] +is_a: GO:2000771 ! positive regulation of establishment or maintenance of cell polarity regulating cell shape +is_a: GO:2000782 ! regulation of establishment of cell polarity regulating cell shape +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071964 ! establishment of cell polarity regulating cell shape +relationship: positively_regulates GO:0071964 ! establishment of cell polarity regulating cell shape +created_by: mah +creation_date: 2011-06-23T12:17:48Z + +[Term] +id: GO:2000785 +name: regulation of autophagosome assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of autophagosome assembly." [GOC:autophagy, GOC:BHF] +synonym: "regulation of autophagic vacuole assembly" EXACT [GOC:autophagy] +synonym: "regulation of autophagic vacuole formation" RELATED [GOC:obol] +synonym: "regulation of autophagosome biosynthesis" EXACT [GOC:obol] +synonym: "regulation of autophagosome formation" EXACT [GOC:obol] +synonym: "regulation of PAS formation" RELATED [GOC:obol] +is_a: GO:0016241 ! regulation of macroautophagy +is_a: GO:0044088 ! regulation of vacuole organization +is_a: GO:1902115 ! regulation of organelle assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0000045 ! autophagosome assembly +relationship: regulates GO:0000045 ! autophagosome assembly +created_by: rl +creation_date: 2011-06-24T11:19:08Z + +[Term] +id: GO:2000786 +name: positive regulation of autophagosome assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly." [GOC:autophagy, GOC:BHF] +synonym: "positive regulation of autophagic vacuole assembly" EXACT [GOC:autophagy] +synonym: "positive regulation of autophagic vacuole formation" RELATED [GOC:obol] +synonym: "positive regulation of autophagosome biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of autophagosome formation" EXACT [GOC:obol] +synonym: "positive regulation of PAS formation" RELATED [GOC:obol] +is_a: GO:0016239 ! positive regulation of macroautophagy +is_a: GO:0044090 ! positive regulation of vacuole organization +is_a: GO:1902117 ! positive regulation of organelle assembly +is_a: GO:2000785 ! regulation of autophagosome assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000045 ! autophagosome assembly +relationship: positively_regulates GO:0000045 ! autophagosome assembly +created_by: rl +creation_date: 2011-06-24T11:19:12Z + +[Term] +id: GO:2000787 +name: regulation of venous endothelial cell fate commitment +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment." [PMID:11585794] +is_a: GO:0010453 ! regulation of cell fate commitment +is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060845 ! venous endothelial cell fate commitment +relationship: regulates GO:0060845 ! venous endothelial cell fate commitment +created_by: bf +creation_date: 2011-06-24T01:26:12Z + +[Term] +id: GO:2000788 +name: negative regulation of venous endothelial cell fate commitment +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment." [PMID:11585794] +is_a: GO:0010454 ! negative regulation of cell fate commitment +is_a: GO:0110059 ! negative regulation of blood vessel endothelial cell differentiation +is_a: GO:2000787 ! regulation of venous endothelial cell fate commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060845 ! venous endothelial cell fate commitment +relationship: negatively_regulates GO:0060845 ! venous endothelial cell fate commitment +created_by: bf +creation_date: 2011-06-24T01:26:16Z + +[Term] +id: GO:2000789 +name: positive regulation of venous endothelial cell fate commitment +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment." [PMID:11585794] +is_a: GO:0010455 ! positive regulation of cell fate commitment +is_a: GO:0110058 ! positive regulation of blood vessel endothelial cell differentiation +is_a: GO:2000787 ! regulation of venous endothelial cell fate commitment +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060845 ! venous endothelial cell fate commitment +relationship: positively_regulates GO:0060845 ! venous endothelial cell fate commitment +created_by: bf +creation_date: 2011-06-24T01:26:19Z + +[Term] +id: GO:2000790 +name: regulation of mesenchymal cell proliferation involved in lung development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] +is_a: GO:0010464 ! regulation of mesenchymal cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +relationship: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +created_by: pr +creation_date: 2011-06-24T01:53:50Z + +[Term] +id: GO:2000791 +name: negative regulation of mesenchymal cell proliferation involved in lung development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation +is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +relationship: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +created_by: pr +creation_date: 2011-06-24T01:53:53Z + +[Term] +id: GO:2000792 +name: positive regulation of mesenchymal cell proliferation involved in lung development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] +is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +relationship: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development +created_by: pr +creation_date: 2011-06-24T01:53:56Z + +[Term] +id: GO:2000793 +name: cell proliferation involved in heart valve development +namespace: biological_process +def: "Any cell proliferation that is involved in heart valve development." [GOC:BHF] +synonym: "cell proliferation of cardiac valve development" EXACT [GOC:obol] +synonym: "cell proliferation of heart valve development" EXACT [GOC:obol] +is_a: GO:0008283 ! cell population proliferation +intersection_of: GO:0008283 ! cell population proliferation +intersection_of: part_of GO:0003170 ! heart valve development +relationship: part_of GO:0003170 ! heart valve development +created_by: bf +creation_date: 2011-06-24T03:12:15Z + +[Term] +id: GO:2000794 +name: regulation of epithelial cell proliferation involved in lung morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +relationship: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +created_by: pr +creation_date: 2011-06-25T07:22:38Z + +[Term] +id: GO:2000795 +name: negative regulation of epithelial cell proliferation involved in lung morphogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +relationship: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis +created_by: pr +creation_date: 2011-06-25T07:22:42Z + +[Term] +id: GO:2000796 +name: Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment +namespace: biological_process +def: "Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment." [PMID:11585794] +synonym: "N signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +synonym: "Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +synonym: "Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +synonym: "Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +synonym: "Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +synonym: "Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment" EXACT [GOC:obol] +is_a: GO:0007219 ! Notch signaling pathway +intersection_of: GO:0007219 ! Notch signaling pathway +intersection_of: part_of GO:2000788 ! negative regulation of venous endothelial cell fate commitment +relationship: part_of GO:2000788 ! negative regulation of venous endothelial cell fate commitment +created_by: bf +creation_date: 2011-06-27T09:07:42Z + +[Term] +id: GO:2000797 +name: regulation of amniotic stem cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation." [GOC:obol] +is_a: GO:2000739 ! regulation of mesenchymal stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097086 ! amniotic stem cell differentiation +relationship: regulates GO:0097086 ! amniotic stem cell differentiation +created_by: yaf +creation_date: 2011-06-29T02:18:59Z + +[Term] +id: GO:2000798 +name: negative regulation of amniotic stem cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation." [GOC:obol] +is_a: GO:2000740 ! negative regulation of mesenchymal stem cell differentiation +is_a: GO:2000797 ! regulation of amniotic stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097086 ! amniotic stem cell differentiation +relationship: negatively_regulates GO:0097086 ! amniotic stem cell differentiation +created_by: yaf +creation_date: 2011-06-29T02:19:03Z + +[Term] +id: GO:2000799 +name: positive regulation of amniotic stem cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation." [GOC:obol] +is_a: GO:2000741 ! positive regulation of mesenchymal stem cell differentiation +is_a: GO:2000797 ! regulation of amniotic stem cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097086 ! amniotic stem cell differentiation +relationship: positively_regulates GO:0097086 ! amniotic stem cell differentiation +created_by: yaf +creation_date: 2011-06-29T02:19:06Z + +[Term] +id: GO:2000800 +name: regulation of endocardial cushion to mesenchymal transition involved in heart valve formation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation." [GOC:BHF] +synonym: "regulation of endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:obol] +is_a: GO:0140049 ! regulation of endocardial cushion to mesenchymal transition +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +relationship: regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +created_by: bf +creation_date: 2011-07-01T12:31:18Z + +[Term] +id: GO:2000801 +name: negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation." [GOC:BHF] +synonym: "negative regulation of endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:obol] +is_a: GO:0140050 ! negative regulation of endocardial cushion to mesenchymal transition +is_a: GO:2000800 ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +relationship: negatively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +created_by: bf +creation_date: 2011-07-01T12:31:22Z + +[Term] +id: GO:2000802 +name: positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation." [GOC:BHF] +synonym: "positive regulation of endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:obol] +is_a: GO:0140051 ! positive regulation of endocardial cushion to mesenchymal transition +is_a: GO:2000800 ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +relationship: positively_regulates GO:0003199 ! endocardial cushion to mesenchymal transition involved in heart valve formation +created_by: bf +creation_date: 2011-07-01T12:31:25Z + +[Term] +id: GO:2000803 +name: endosomal signal transduction +namespace: biological_process +def: "The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction." [GOC:bf, GOC:signaling, PMID:15084302, PMID:17662591] +synonym: "endosome-based signaling" EXACT [PMID:17662591] +synonym: "signaling cascade in endosome" RELATED [GOC:obol] +synonym: "signaling from endosome" EXACT [PMID:17662591] +synonym: "signaling pathway in endosome" RELATED [GOC:obol] +synonym: "signalling cascade in endosome" RELATED [GOC:obol] +synonym: "signalling pathway in endosome" RELATED [GOC:obol] +is_a: GO:0035556 ! intracellular signal transduction +intersection_of: GO:0007165 ! signal transduction +intersection_of: occurs_in GO:0005768 ! endosome +relationship: occurs_in GO:0005768 ! endosome +created_by: bf +creation_date: 2011-07-01T03:45:12Z + +[Term] +id: GO:2000804 +name: regulation of termination of RNA polymerase II transcription, poly(A)-coupled +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled." [GOC:obol] +synonym: "regulation of termination of RNA polymerase II transcription, polyadenylation-coupled" RELATED [] +synonym: "regulation of transcription termination from Pol II promoter, poly(A) coupled" RELATED [GOC:obol] +synonym: "regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled" RELATED [GOC:obol] +is_a: GO:1904594 ! regulation of termination of RNA polymerase II transcription +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +relationship: regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +created_by: pr +creation_date: 2011-07-04T08:41:27Z + +[Term] +id: GO:2000805 +name: negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled." [GOC:obol] +synonym: "negative regulation of termination of RNA polymerase II transcription, polyadenylation-coupled" RELATED [] +synonym: "negative regulation of transcription termination from Pol II promoter, poly(A) coupled" RELATED [GOC:obol] +synonym: "negative regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled" RELATED [GOC:obol] +is_a: GO:0120191 ! negative regulation of termination of RNA polymerase II transcription +is_a: GO:2000804 ! regulation of termination of RNA polymerase II transcription, poly(A)-coupled +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +relationship: negatively_regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +created_by: pr +creation_date: 2011-07-04T08:41:34Z + +[Term] +id: GO:2000806 +name: positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled." [GOC:obol] +synonym: "positive regulation of termination of RNA polymerase II transcription, polyadenylation-coupled" RELATED [] +synonym: "positive regulation of transcription termination from Pol II promoter, poly(A) coupled" RELATED [GOC:obol] +synonym: "positive regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled" RELATED [GOC:obol] +is_a: GO:1904595 ! positive regulation of termination of RNA polymerase II transcription +is_a: GO:2000804 ! regulation of termination of RNA polymerase II transcription, poly(A)-coupled +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +relationship: positively_regulates GO:0030846 ! termination of RNA polymerase II transcription, poly(A)-coupled +created_by: pr +creation_date: 2011-07-04T08:41:39Z + +[Term] +id: GO:2000807 +name: regulation of synaptic vesicle clustering +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of synaptic vesicle clustering." [PMID:21513708] +is_a: GO:0098693 ! regulation of synaptic vesicle cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097091 ! synaptic vesicle clustering +relationship: regulates GO:0097091 ! synaptic vesicle clustering +created_by: pr +creation_date: 2011-07-06T09:50:30Z + +[Term] +id: GO:2000808 +name: negative regulation of synaptic vesicle clustering +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering." [PMID:21513708] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:2000807 ! regulation of synaptic vesicle clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097091 ! synaptic vesicle clustering +relationship: negatively_regulates GO:0097091 ! synaptic vesicle clustering +created_by: pr +creation_date: 2011-07-06T09:50:34Z + +[Term] +id: GO:2000809 +name: positive regulation of synaptic vesicle clustering +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering." [PMID:21513708] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:2000807 ! regulation of synaptic vesicle clustering +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097091 ! synaptic vesicle clustering +relationship: positively_regulates GO:0097091 ! synaptic vesicle clustering +created_by: pr +creation_date: 2011-07-06T09:50:37Z + +[Term] +id: GO:2000810 +name: regulation of bicellular tight junction assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tight junction assembly." [GOC:BHF] +synonym: "regulation of tight junction formation" EXACT [GOC:obol] +is_a: GO:1901888 ! regulation of cell junction assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0070830 ! bicellular tight junction assembly +relationship: regulates GO:0070830 ! bicellular tight junction assembly +created_by: vk +creation_date: 2011-07-06T01:08:28Z + +[Term] +id: GO:2000811 +name: negative regulation of anoikis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of anoikis." [GOC:obol] +synonym: "negative regulation of detachment induced cell death" EXACT [GOC:obol] +synonym: "negative regulation of suspension induced apoptosis" EXACT [GOC:obol] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:2000209 ! regulation of anoikis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0043276 ! anoikis +relationship: negatively_regulates GO:0043276 ! anoikis +created_by: pr +creation_date: 2011-07-07T09:42:20Z + +[Term] +id: GO:2000812 +name: regulation of barbed-end actin filament capping +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of barbed-end actin filament capping." [GOC:BHF] +synonym: "regulation of barbed-end actin capping activity" EXACT [GOC:obol] +synonym: "regulation of barbed-end F-actin capping activity" EXACT [GOC:obol] +synonym: "regulation of plus-end actin filament capping activity" EXACT [GOC:obol] +synonym: "regulation of plus-end F-actin capping activity" EXACT [GOC:obol] +is_a: GO:0030833 ! regulation of actin filament polymerization +is_a: GO:0030834 ! regulation of actin filament depolymerization +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051016 ! barbed-end actin filament capping +relationship: regulates GO:0051016 ! barbed-end actin filament capping +created_by: rl +creation_date: 2011-07-07T04:08:13Z + +[Term] +id: GO:2000813 +name: negative regulation of barbed-end actin filament capping +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping." [GOC:BHF] +synonym: "negative regulation of barbed-end actin capping activity" EXACT [GOC:obol] +synonym: "negative regulation of barbed-end F-actin capping activity" EXACT [GOC:obol] +synonym: "negative regulation of plus-end actin filament capping activity" EXACT [GOC:obol] +synonym: "negative regulation of plus-end F-actin capping activity" EXACT [GOC:obol] +is_a: GO:0030836 ! positive regulation of actin filament depolymerization +is_a: GO:0030838 ! positive regulation of actin filament polymerization +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:2000812 ! regulation of barbed-end actin filament capping +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051016 ! barbed-end actin filament capping +relationship: negatively_regulates GO:0051016 ! barbed-end actin filament capping +created_by: rl +creation_date: 2011-07-07T04:08:18Z + +[Term] +id: GO:2000814 +name: positive regulation of barbed-end actin filament capping +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping." [GOC:BHF] +synonym: "positive regulation of barbed-end actin capping activity" EXACT [GOC:obol] +synonym: "positive regulation of barbed-end F-actin capping activity" EXACT [GOC:obol] +synonym: "positive regulation of plus-end actin filament capping activity" EXACT [GOC:obol] +synonym: "positive regulation of plus-end F-actin capping activity" EXACT [GOC:obol] +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:2000812 ! regulation of barbed-end actin filament capping +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051016 ! barbed-end actin filament capping +relationship: positively_regulates GO:0051016 ! barbed-end actin filament capping +created_by: rl +creation_date: 2011-07-07T04:08:23Z + +[Term] +id: GO:2000815 +name: regulation of mRNA stability involved in response to oxidative stress +namespace: biological_process +def: "A process of regulation of mRNA stability that is involved in a response to oxidative stress." [GOC:obol] +is_a: GO:0010610 ! regulation of mRNA stability involved in response to stress +intersection_of: GO:0043488 ! regulation of mRNA stability +intersection_of: part_of GO:0006979 ! response to oxidative stress +relationship: part_of GO:0006979 ! response to oxidative stress +created_by: mah +creation_date: 2011-07-11T04:40:56Z + +[Term] +id: GO:2000816 +name: negative regulation of mitotic sister chromatid separation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation." [GOC:obol] +synonym: "negative regulation of chromosome separation during mitosis" RELATED [GOC:obol] +synonym: "negative regulation of mitotic chromosome separation" RELATED [GOC:obol] +synonym: "negative regulation of mitotic sister chromatid resolution" EXACT [GOC:obol] +synonym: "negative regulation of sister chromatid separation during mitosis" EXACT [GOC:obol] +is_a: GO:0010965 ! regulation of mitotic sister chromatid separation +is_a: GO:0033048 ! negative regulation of mitotic sister chromatid segregation +is_a: GO:1905819 ! negative regulation of chromosome separation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051306 ! mitotic sister chromatid separation +relationship: negatively_regulates GO:0051306 ! mitotic sister chromatid separation +created_by: mah +creation_date: 2011-07-11T04:45:06Z + +[Term] +id: GO:2000817 +name: regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore +namespace: biological_process +def: "Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore." [GOC:obol] +synonym: "regulation of histone H3-T3 phosphorylation involved in chromosomal passenger complex localization to kinetochore" EXACT [GOC:obol] +synonym: "regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localisation to kinetochore" RELATED [GOC:obol] +synonym: "regulation of histone H3-T3 phosphorylation involved in CPC complex localization to kinetochore" EXACT [GOC:obol] +synonym: "regulation of histone H3-T3 phosphorylation involved in CPC localization to kinetochore" EXACT [GOC:obol] +is_a: GO:2000281 ! regulation of histone H3-T3 phosphorylation +intersection_of: GO:2000281 ! regulation of histone H3-T3 phosphorylation +intersection_of: part_of GO:0072356 ! chromosome passenger complex localization to kinetochore +relationship: part_of GO:0072356 ! chromosome passenger complex localization to kinetochore +created_by: mah +creation_date: 2011-07-12T11:37:40Z + +[Term] +id: GO:2000818 +name: negative regulation of myoblast proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol] +is_a: GO:0008285 ! negative regulation of cell population proliferation +is_a: GO:2000291 ! regulation of myoblast proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051450 ! myoblast proliferation +relationship: negatively_regulates GO:0051450 ! myoblast proliferation +created_by: pr +creation_date: 2011-07-12T03:06:04Z + +[Term] +id: GO:2000819 +name: regulation of nucleotide-excision repair +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of nucleotide-excision repair." [GOC:jp, PMID:18836076] +synonym: "regulation of interstrand crosslink repair" RELATED [GOC:obol] +synonym: "regulation of intrastrand cross-link repair" RELATED [GOC:obol] +synonym: "regulation of NER" EXACT [GOC:obol] +synonym: "regulation of pyrimidine-dimer repair, DNA damage excision" EXACT [GOC:obol] +is_a: GO:0006282 ! regulation of DNA repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006289 ! nucleotide-excision repair +relationship: regulates GO:0006289 ! nucleotide-excision repair +created_by: pr +creation_date: 2011-07-13T08:55:39Z + +[Term] +id: GO:2000820 +name: negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation +namespace: biological_process +def: "Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation." [GOC:BHF] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation" RELATED [GOC:obol] +synonym: "negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation" EXACT [GOC:obol] +synonym: "negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation" EXACT [GOC:obol] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation" RELATED [GOC:obol] +synonym: "negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation" RELATED [GOC:obol] +is_a: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II +intersection_of: part_of GO:0051145 ! smooth muscle cell differentiation +relationship: part_of GO:0051145 ! smooth muscle cell differentiation +created_by: bf +creation_date: 2011-07-14T08:25:05Z + +[Term] +id: GO:2000821 +name: regulation of grooming behavior +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of grooming behavior." [GOC:BHF] +synonym: "regulation of grooming behaviour" EXACT [GOC:obol] +is_a: GO:0050795 ! regulation of behavior +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007625 ! grooming behavior +relationship: regulates GO:0007625 ! grooming behavior +created_by: rl +creation_date: 2011-07-14T04:48:12Z + +[Term] +id: GO:2000822 +name: regulation of behavioral fear response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of behavioral fear response." [GOC:BHF] +synonym: "regulation of behavioural fear response" EXACT [GOC:obol] +is_a: GO:0031347 ! regulation of defense response +is_a: GO:0050795 ! regulation of behavior +is_a: GO:1903365 ! regulation of fear response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001662 ! behavioral fear response +relationship: regulates GO:0001662 ! behavioral fear response +created_by: rl +creation_date: 2011-07-14T04:50:47Z + +[Term] +id: GO:2000825 +name: positive regulation of androgen receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of androgen receptor activity." [GOC:obol] +is_a: GO:0006357 ! regulation of transcription by RNA polymerase II +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004879 ! nuclear receptor activity +relationship: positively_regulates GO:0004879 ! nuclear receptor activity +created_by: yaf +creation_date: 2011-07-15T10:56:14Z + +[Term] +id: GO:2000826 +name: regulation of heart morphogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF] +synonym: "regulation of cardiac morphogenesis" RELATED [GOC:obol] +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003007 ! heart morphogenesis +relationship: regulates GO:0003007 ! heart morphogenesis +created_by: vk +creation_date: 2011-07-19T10:08:58Z + +[Term] +id: GO:2000827 +name: mitochondrial RNA surveillance +namespace: biological_process +def: "The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion." [PMID:19864255] +synonym: "aberrant RNA catabolic process in mitochondria" EXACT [GOC:obol] +synonym: "aberrant RNA catabolic process in mitochondrion" EXACT [GOC:obol] +synonym: "RNA quality control in mitochondria" EXACT [GOC:obol] +synonym: "RNA quality control in mitochondrion" EXACT [GOC:obol] +synonym: "RNA surveillance in mitochondria" EXACT [GOC:obol] +is_a: GO:0000957 ! mitochondrial RNA catabolic process +is_a: GO:0071026 ! cytoplasmic RNA surveillance +intersection_of: GO:0071025 ! RNA surveillance +intersection_of: occurs_in GO:0005739 ! mitochondrion +created_by: bf +creation_date: 2011-07-20T01:33:23Z + +[Term] +id: GO:2000828 +name: regulation of parathyroid hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of parathyroid hormone secretion." [GOC:obol] +synonym: "regulation of parathormone secretion" EXACT [GOC:obol] +synonym: "regulation of parathyrin secretion" EXACT [GOC:obol] +synonym: "regulation of PTH secretion" EXACT [GOC:obol] +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035898 ! parathyroid hormone secretion +relationship: regulates GO:0035898 ! parathyroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:37:53Z + +[Term] +id: GO:2000829 +name: negative regulation of parathyroid hormone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion." [GOC:obol] +synonym: "negative regulation of parathormone secretion" EXACT [GOC:obol] +synonym: "negative regulation of parathyrin secretion" EXACT [GOC:obol] +synonym: "negative regulation of PTH secretion" EXACT [GOC:obol] +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000828 ! regulation of parathyroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035898 ! parathyroid hormone secretion +relationship: negatively_regulates GO:0035898 ! parathyroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:37:57Z + +[Term] +id: GO:2000830 +name: positive regulation of parathyroid hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion." [GOC:obol] +synonym: "positive regulation of parathormone secretion" EXACT [GOC:obol] +synonym: "positive regulation of parathyrin secretion" EXACT [GOC:obol] +synonym: "positive regulation of PTH secretion" EXACT [GOC:obol] +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000828 ! regulation of parathyroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035898 ! parathyroid hormone secretion +relationship: positively_regulates GO:0035898 ! parathyroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:38:00Z + +[Term] +id: GO:2000831 +name: regulation of steroid hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0044060 ! regulation of endocrine process +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035929 ! steroid hormone secretion +relationship: regulates GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:38:46Z + +[Term] +id: GO:2000832 +name: negative regulation of steroid hormone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035929 ! steroid hormone secretion +relationship: negatively_regulates GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:38:50Z + +[Term] +id: GO:2000833 +name: positive regulation of steroid hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035929 ! steroid hormone secretion +relationship: positively_regulates GO:0035929 ! steroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:38:51Z + +[Term] +id: GO:2000834 +name: regulation of androgen secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl] +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035935 ! androgen secretion +relationship: regulates GO:0035935 ! androgen secretion +created_by: bf +creation_date: 2011-07-26T08:39:45Z + +[Term] +id: GO:2000835 +name: negative regulation of androgen secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl] +is_a: GO:2000832 ! negative regulation of steroid hormone secretion +is_a: GO:2000834 ! regulation of androgen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035935 ! androgen secretion +relationship: negatively_regulates GO:0035935 ! androgen secretion +created_by: bf +creation_date: 2011-07-26T08:39:48Z + +[Term] +id: GO:2000836 +name: positive regulation of androgen secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl] +is_a: GO:2000833 ! positive regulation of steroid hormone secretion +is_a: GO:2000834 ! regulation of androgen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035935 ! androgen secretion +relationship: positively_regulates GO:0035935 ! androgen secretion +created_by: bf +creation_date: 2011-07-26T08:39:51Z + +[Term] +id: GO:2000837 +name: regulation of androstenedione secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of androstenedione secretion." [GOC:sl] +synonym: "regulation of androst-4-ene-3,17-dione secretion" EXACT [GOC:obol] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035941 ! androstenedione secretion +relationship: regulates GO:0035941 ! androstenedione secretion +created_by: bf +creation_date: 2011-07-26T08:40:36Z + +[Term] +id: GO:2000838 +name: negative regulation of androstenedione secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion." [GOC:sl] +synonym: "negative regulation of androst-4-ene-3,17-dione secretion" EXACT [GOC:obol] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:2000837 ! regulation of androstenedione secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035941 ! androstenedione secretion +relationship: negatively_regulates GO:0035941 ! androstenedione secretion +created_by: bf +creation_date: 2011-07-26T08:40:40Z + +[Term] +id: GO:2000839 +name: positive regulation of androstenedione secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of androstenedione secretion." [GOC:sl] +synonym: "positive regulation of androst-4-ene-3,17-dione secretion" EXACT [GOC:obol] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:2000837 ! regulation of androstenedione secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035941 ! androstenedione secretion +relationship: positively_regulates GO:0035941 ! androstenedione secretion +created_by: bf +creation_date: 2011-07-26T08:40:42Z + +[Term] +id: GO:2000840 +name: regulation of dehydroepiandrosterone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion." [GOC:sl] +synonym: "regulation of 3beta-hydroxyandrost-5-en-17-one secretion" EXACT [GOC:obol] +synonym: "regulation of dehydroisoandrosterone secretion" EXACT [GOC:obol] +synonym: "regulation of DHEA secretion" EXACT [GOC:obol] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035942 ! dehydroepiandrosterone secretion +relationship: regulates GO:0035942 ! dehydroepiandrosterone secretion +created_by: bf +creation_date: 2011-07-26T08:41:29Z + +[Term] +id: GO:2000841 +name: negative regulation of dehydroepiandrosterone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion." [GOC:sl] +synonym: "negative regulation of 3beta-hydroxyandrost-5-en-17-one secretion" EXACT [GOC:obol] +synonym: "negative regulation of dehydroisoandrosterone secretion" EXACT [GOC:obol] +synonym: "negative regulation of DHEA secretion" EXACT [GOC:obol] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:2000840 ! regulation of dehydroepiandrosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035942 ! dehydroepiandrosterone secretion +relationship: negatively_regulates GO:0035942 ! dehydroepiandrosterone secretion +created_by: bf +creation_date: 2011-07-26T08:41:33Z + +[Term] +id: GO:2000842 +name: positive regulation of dehydroepiandrosterone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion." [GOC:sl] +synonym: "positive regulation of 3beta-hydroxyandrost-5-en-17-one secretion" EXACT [GOC:obol] +synonym: "positive regulation of dehydroisoandrosterone secretion" EXACT [GOC:obol] +synonym: "positive regulation of DHEA secretion" EXACT [GOC:obol] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:2000840 ! regulation of dehydroepiandrosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035942 ! dehydroepiandrosterone secretion +relationship: positively_regulates GO:0035942 ! dehydroepiandrosterone secretion +created_by: bf +creation_date: 2011-07-26T08:41:36Z + +[Term] +id: GO:2000843 +name: regulation of testosterone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of testosterone secretion." [GOC:sl] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035936 ! testosterone secretion +relationship: regulates GO:0035936 ! testosterone secretion +created_by: bf +creation_date: 2011-07-26T08:42:29Z + +[Term] +id: GO:2000844 +name: negative regulation of testosterone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion." [GOC:sl] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:2000843 ! regulation of testosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035936 ! testosterone secretion +relationship: negatively_regulates GO:0035936 ! testosterone secretion +created_by: bf +creation_date: 2011-07-26T08:42:33Z + +[Term] +id: GO:2000845 +name: positive regulation of testosterone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of testosterone secretion." [GOC:sl] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:2000843 ! regulation of testosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035936 ! testosterone secretion +relationship: positively_regulates GO:0035936 ! testosterone secretion +created_by: bf +creation_date: 2011-07-26T08:42:36Z + +[Term] +id: GO:2000846 +name: regulation of corticosteroid hormone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion." [GOC:sl] +synonym: "regulation of corticosteroid secretion" RELATED [GOC:obol] +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035930 ! corticosteroid hormone secretion +relationship: regulates GO:0035930 ! corticosteroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:43:38Z + +[Term] +id: GO:2000847 +name: negative regulation of corticosteroid hormone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion." [GOC:sl] +synonym: "negative regulation of corticosteroid secretion" RELATED [GOC:obol] +is_a: GO:2000832 ! negative regulation of steroid hormone secretion +is_a: GO:2000846 ! regulation of corticosteroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035930 ! corticosteroid hormone secretion +relationship: negatively_regulates GO:0035930 ! corticosteroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:43:42Z + +[Term] +id: GO:2000848 +name: positive regulation of corticosteroid hormone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion." [GOC:sl] +synonym: "positive regulation of corticosteroid secretion" RELATED [GOC:obol] +is_a: GO:2000833 ! positive regulation of steroid hormone secretion +is_a: GO:2000846 ! regulation of corticosteroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035930 ! corticosteroid hormone secretion +relationship: positively_regulates GO:0035930 ! corticosteroid hormone secretion +created_by: bf +creation_date: 2011-07-26T08:43:45Z + +[Term] +id: GO:2000849 +name: regulation of glucocorticoid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucocorticoid secretion." [GOC:sl] +is_a: GO:2000846 ! regulation of corticosteroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035933 ! glucocorticoid secretion +relationship: regulates GO:0035933 ! glucocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:44:43Z + +[Term] +id: GO:2000850 +name: negative regulation of glucocorticoid secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion." [GOC:sl] +is_a: GO:2000847 ! negative regulation of corticosteroid hormone secretion +is_a: GO:2000849 ! regulation of glucocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035933 ! glucocorticoid secretion +relationship: negatively_regulates GO:0035933 ! glucocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:44:48Z + +[Term] +id: GO:2000851 +name: positive regulation of glucocorticoid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion." [GOC:sl] +is_a: GO:2000848 ! positive regulation of corticosteroid hormone secretion +is_a: GO:2000849 ! regulation of glucocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035933 ! glucocorticoid secretion +relationship: positively_regulates GO:0035933 ! glucocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:44:51Z + +[Term] +id: GO:2000852 +name: regulation of corticosterone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of corticosterone secretion." [GOC:sl] +is_a: GO:2000849 ! regulation of glucocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035934 ! corticosterone secretion +relationship: regulates GO:0035934 ! corticosterone secretion +created_by: bf +creation_date: 2011-07-26T08:45:40Z + +[Term] +id: GO:2000853 +name: negative regulation of corticosterone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion." [GOC:sl] +is_a: GO:2000850 ! negative regulation of glucocorticoid secretion +is_a: GO:2000852 ! regulation of corticosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035934 ! corticosterone secretion +relationship: negatively_regulates GO:0035934 ! corticosterone secretion +created_by: bf +creation_date: 2011-07-26T08:45:43Z + +[Term] +id: GO:2000854 +name: positive regulation of corticosterone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of corticosterone secretion." [GOC:sl] +is_a: GO:2000851 ! positive regulation of glucocorticoid secretion +is_a: GO:2000852 ! regulation of corticosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035934 ! corticosterone secretion +relationship: positively_regulates GO:0035934 ! corticosterone secretion +created_by: bf +creation_date: 2011-07-26T08:45:45Z + +[Term] +id: GO:2000855 +name: regulation of mineralocorticoid secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mineralocorticoid secretion." [GOC:sl] +is_a: GO:2000846 ! regulation of corticosteroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035931 ! mineralocorticoid secretion +relationship: regulates GO:0035931 ! mineralocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:46:38Z + +[Term] +id: GO:2000856 +name: negative regulation of mineralocorticoid secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion." [GOC:sl] +is_a: GO:2000847 ! negative regulation of corticosteroid hormone secretion +is_a: GO:2000855 ! regulation of mineralocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035931 ! mineralocorticoid secretion +relationship: negatively_regulates GO:0035931 ! mineralocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:46:42Z + +[Term] +id: GO:2000857 +name: positive regulation of mineralocorticoid secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion." [GOC:sl] +is_a: GO:2000848 ! positive regulation of corticosteroid hormone secretion +is_a: GO:2000855 ! regulation of mineralocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035931 ! mineralocorticoid secretion +relationship: positively_regulates GO:0035931 ! mineralocorticoid secretion +created_by: bf +creation_date: 2011-07-26T08:46:45Z + +[Term] +id: GO:2000858 +name: regulation of aldosterone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of aldosterone secretion." [GOC:sl] +is_a: GO:2000855 ! regulation of mineralocorticoid secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035932 ! aldosterone secretion +relationship: regulates GO:0035932 ! aldosterone secretion +created_by: bf +creation_date: 2011-07-26T08:47:27Z + +[Term] +id: GO:2000859 +name: negative regulation of aldosterone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion." [GOC:sl] +is_a: GO:2000856 ! negative regulation of mineralocorticoid secretion +is_a: GO:2000858 ! regulation of aldosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035932 ! aldosterone secretion +relationship: negatively_regulates GO:0035932 ! aldosterone secretion +created_by: bf +creation_date: 2011-07-26T08:47:31Z + +[Term] +id: GO:2000860 +name: positive regulation of aldosterone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of aldosterone secretion." [GOC:sl] +is_a: GO:2000857 ! positive regulation of mineralocorticoid secretion +is_a: GO:2000858 ! regulation of aldosterone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035932 ! aldosterone secretion +relationship: positively_regulates GO:0035932 ! aldosterone secretion +created_by: bf +creation_date: 2011-07-26T08:47:34Z + +[Term] +id: GO:2000861 +name: regulation of estrogen secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of estrogen secretion." [GOC:sl] +synonym: "regulation of oestrogen secretion" RELATED [GOC:obol] +is_a: GO:2000831 ! regulation of steroid hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035937 ! estrogen secretion +relationship: regulates GO:0035937 ! estrogen secretion +created_by: bf +creation_date: 2011-07-26T08:48:24Z + +[Term] +id: GO:2000862 +name: negative regulation of estrogen secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion." [GOC:sl] +synonym: "negative regulation of oestrogen secretion" RELATED [GOC:obol] +is_a: GO:2000832 ! negative regulation of steroid hormone secretion +is_a: GO:2000861 ! regulation of estrogen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035937 ! estrogen secretion +relationship: negatively_regulates GO:0035937 ! estrogen secretion +created_by: bf +creation_date: 2011-07-26T08:48:28Z + +[Term] +id: GO:2000863 +name: positive regulation of estrogen secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of estrogen secretion." [GOC:sl] +synonym: "positive regulation of oestrogen secretion" RELATED [GOC:obol] +is_a: GO:2000833 ! positive regulation of steroid hormone secretion +is_a: GO:2000861 ! regulation of estrogen secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035937 ! estrogen secretion +relationship: positively_regulates GO:0035937 ! estrogen secretion +created_by: bf +creation_date: 2011-07-26T08:48:31Z + +[Term] +id: GO:2000864 +name: regulation of estradiol secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of estradiol secretion." [GOC:sl] +synonym: "regulation of oestradiol secretion" EXACT [GOC:obol] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0046883 ! regulation of hormone secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035938 ! estradiol secretion +relationship: regulates GO:0035938 ! estradiol secretion +created_by: bf +creation_date: 2011-07-26T08:49:13Z + +[Term] +id: GO:2000865 +name: negative regulation of estradiol secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion." [GOC:sl] +synonym: "negative regulation of oestradiol secretion" EXACT [GOC:obol] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:2000864 ! regulation of estradiol secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035938 ! estradiol secretion +relationship: negatively_regulates GO:0035938 ! estradiol secretion +created_by: bf +creation_date: 2011-07-26T08:49:17Z + +[Term] +id: GO:2000866 +name: positive regulation of estradiol secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of estradiol secretion." [GOC:sl] +synonym: "positive regulation of oestradiol secretion" EXACT [GOC:obol] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:2000864 ! regulation of estradiol secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035938 ! estradiol secretion +relationship: positively_regulates GO:0035938 ! estradiol secretion +created_by: bf +creation_date: 2011-07-26T08:49:20Z + +[Term] +id: GO:2000867 +name: regulation of estrone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of estrone secretion." [GOC:sl] +synonym: "regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion" EXACT [GOC:obol] +synonym: "regulation of folliculin secretion" EXACT [GOC:obol] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0046883 ! regulation of hormone secretion +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035943 ! estrone secretion +relationship: regulates GO:0035943 ! estrone secretion +created_by: bf +creation_date: 2011-07-26T08:50:11Z + +[Term] +id: GO:2000868 +name: negative regulation of estrone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion." [GOC:sl] +synonym: "negative regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion" EXACT [GOC:obol] +synonym: "negative regulation of folliculin secretion" EXACT [GOC:obol] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:0046888 ! negative regulation of hormone secretion +is_a: GO:2000867 ! regulation of estrone secretion +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035943 ! estrone secretion +relationship: negatively_regulates GO:0035943 ! estrone secretion +created_by: bf +creation_date: 2011-07-26T08:50:16Z + +[Term] +id: GO:2000869 +name: positive regulation of estrone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of estrone secretion." [GOC:sl] +synonym: "positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion" EXACT [GOC:obol] +synonym: "positive regulation of folliculin secretion" EXACT [GOC:obol] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:0046887 ! positive regulation of hormone secretion +is_a: GO:2000867 ! regulation of estrone secretion +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035943 ! estrone secretion +relationship: positively_regulates GO:0035943 ! estrone secretion +created_by: bf +creation_date: 2011-07-26T08:50:19Z + +[Term] +id: GO:2000870 +name: regulation of progesterone secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of progesterone secretion." [GOC:sl] +is_a: GO:2000194 ! regulation of female gonad development +is_a: GO:2000831 ! regulation of steroid hormone secretion +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042701 ! progesterone secretion +relationship: regulates GO:0042701 ! progesterone secretion +created_by: bf +creation_date: 2011-07-26T08:51:14Z + +[Term] +id: GO:2000871 +name: negative regulation of progesterone secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion." [GOC:sl] +is_a: GO:2000195 ! negative regulation of female gonad development +is_a: GO:2000832 ! negative regulation of steroid hormone secretion +is_a: GO:2000870 ! regulation of progesterone secretion +is_a: GO:2001024 ! negative regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042701 ! progesterone secretion +relationship: negatively_regulates GO:0042701 ! progesterone secretion +created_by: bf +creation_date: 2011-07-26T08:51:19Z + +[Term] +id: GO:2000872 +name: positive regulation of progesterone secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of progesterone secretion." [GOC:sl] +is_a: GO:2000196 ! positive regulation of female gonad development +is_a: GO:2000833 ! positive regulation of steroid hormone secretion +is_a: GO:2000870 ! regulation of progesterone secretion +is_a: GO:2001025 ! positive regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042701 ! progesterone secretion +relationship: positively_regulates GO:0042701 ! progesterone secretion +created_by: bf +creation_date: 2011-07-26T08:51:22Z + +[Term] +id: GO:2000873 +name: regulation of histone H4 acetylation involved in response to DNA damage stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus." [GOC:mah] +synonym: "regulation of histone H4 acetylation involved in cellular DNA damage response" EXACT [GOC:obol] +synonym: "regulation of histone H4 acetylation involved in cellular response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "regulation of histone H4 acetylation involved in DNA damage response" EXACT [GOC:obol] +synonym: "regulation of histone H4 acetylation involved in response to DNA damage" EXACT [GOC:bf] +synonym: "regulation of histone H4 acetylation involved in response to genotoxic stress" EXACT [GOC:obol] +is_a: GO:0090239 ! regulation of histone H4 acetylation +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000776 ! histone H4 acetylation involved in response to DNA damage stimulus +relationship: regulates GO:2000776 ! histone H4 acetylation involved in response to DNA damage stimulus +created_by: mah +creation_date: 2011-07-26T10:05:23Z + +[Term] +id: GO:2000874 +name: regulation of glyoxylate cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glyoxylate cycle." [GOC:dgf] +synonym: "regulation of glyoxylate bypass" EXACT [GOC:obol] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006097 ! glyoxylate cycle +relationship: regulates GO:0006097 ! glyoxylate cycle +created_by: bf +creation_date: 2011-07-27T01:27:10Z + +[Term] +id: GO:2000875 +name: negative regulation of glyoxylate cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle." [GOC:dgf] +synonym: "negative regulation of glyoxylate bypass" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:2000874 ! regulation of glyoxylate cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006097 ! glyoxylate cycle +relationship: negatively_regulates GO:0006097 ! glyoxylate cycle +created_by: bf +creation_date: 2011-07-27T01:27:15Z + +[Term] +id: GO:2000876 +name: positive regulation of glyoxylate cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glyoxylate cycle." [GOC:dgf] +synonym: "positive regulation of glyoxylate bypass" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:2000874 ! regulation of glyoxylate cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006097 ! glyoxylate cycle +relationship: positively_regulates GO:0006097 ! glyoxylate cycle +created_by: bf +creation_date: 2011-07-27T01:27:18Z + +[Term] +id: GO:2000877 +name: negative regulation of oligopeptide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport." [GOC:obol] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0090088 ! regulation of oligopeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006857 ! oligopeptide transport +relationship: negatively_regulates GO:0006857 ! oligopeptide transport +created_by: bf +creation_date: 2011-07-27T01:54:07Z + +[Term] +id: GO:2000878 +name: positive regulation of oligopeptide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of oligopeptide transport." [GOC:obol] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0090088 ! regulation of oligopeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006857 ! oligopeptide transport +relationship: positively_regulates GO:0006857 ! oligopeptide transport +created_by: bf +creation_date: 2011-07-27T01:54:11Z + +[Term] +id: GO:2000879 +name: negative regulation of dipeptide transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport." [GOC:obol] +is_a: GO:0090089 ! regulation of dipeptide transport +is_a: GO:2000877 ! negative regulation of oligopeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042938 ! dipeptide transport +relationship: negatively_regulates GO:0042938 ! dipeptide transport +created_by: bf +creation_date: 2011-07-27T02:55:21Z + +[Term] +id: GO:2000880 +name: positive regulation of dipeptide transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dipeptide transport." [GOC:obol] +is_a: GO:0090089 ! regulation of dipeptide transport +is_a: GO:2000878 ! positive regulation of oligopeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042938 ! dipeptide transport +relationship: positively_regulates GO:0042938 ! dipeptide transport +created_by: bf +creation_date: 2011-07-27T02:55:24Z + +[Term] +id: GO:2000881 +name: regulation of starch catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of starch catabolic process." [GOC:obol] +synonym: "regulation of starch breakdown" EXACT [GOC:obol] +synonym: "regulation of starch catabolism" EXACT [GOC:obol] +synonym: "regulation of starch degradation" EXACT [GOC:obol] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:2000904 ! regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005983 ! starch catabolic process +relationship: regulates GO:0005983 ! starch catabolic process +created_by: bf +creation_date: 2011-07-27T03:23:39Z + +[Term] +id: GO:2000882 +name: negative regulation of starch catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process." [GOC:obol] +synonym: "negative regulation of starch breakdown" EXACT [GOC:obol] +synonym: "negative regulation of starch catabolism" EXACT [GOC:obol] +synonym: "negative regulation of starch degradation" EXACT [GOC:obol] +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:2000881 ! regulation of starch catabolic process +is_a: GO:2000905 ! negative regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005983 ! starch catabolic process +relationship: negatively_regulates GO:0005983 ! starch catabolic process +created_by: bf +creation_date: 2011-07-27T03:23:46Z + +[Term] +id: GO:2000883 +name: positive regulation of starch catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of starch catabolic process." [GOC:obol] +synonym: "positive regulation of starch breakdown" EXACT [GOC:obol] +synonym: "positive regulation of starch catabolism" EXACT [GOC:obol] +synonym: "positive regulation of starch degradation" EXACT [GOC:obol] +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2000881 ! regulation of starch catabolic process +is_a: GO:2000906 ! positive regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005983 ! starch catabolic process +relationship: positively_regulates GO:0005983 ! starch catabolic process +created_by: bf +creation_date: 2011-07-27T03:23:51Z + +[Term] +id: GO:2000884 +name: glucomannan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a glucomannan." [GOC:mengo_curators] +synonym: "glucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0010391 ! glucomannan metabolic process +is_a: GO:0042737 ! drug catabolic process +created_by: jl +creation_date: 2011-07-28T09:19:03Z + +[Term] +id: GO:2000885 +name: galactoglucomannan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan." [GOC:mengo_curators] +synonym: "galactoglucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0000272 ! polysaccharide catabolic process +is_a: GO:0010392 ! galactoglucomannan metabolic process +created_by: jl +creation_date: 2011-07-28T09:24:11Z + +[Term] +id: GO:2000886 +name: glucuronoxylan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan." [GOC:mengo_curators] +synonym: "glucuronoxylan catabolism" EXACT [GOC:obol] +is_a: GO:0010413 ! glucuronoxylan metabolic process +is_a: GO:0045493 ! xylan catabolic process +created_by: jl +creation_date: 2011-07-28T09:37:06Z + +[Term] +id: GO:2000887 +name: glucuronoarabinoxylan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan." [GOC:mengo_curators] +synonym: "glucuronoarabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:0010414 ! glucuronoarabinoxylan metabolic process +is_a: GO:2000886 ! glucuronoxylan catabolic process +is_a: GO:2000888 ! arabinoxylan-containing compound catabolic process +created_by: jl +creation_date: 2011-07-28T09:39:26Z + +[Term] +id: GO:2000888 +name: arabinoxylan-containing compound catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an arabinoxylan." [GOC:mengo_curators] +synonym: "arabinoxylan catabolic process" RELATED [] +synonym: "arabinoxylan catabolism" RELATED [GOC:obol] +is_a: GO:0010416 ! arabinoxylan-containing compound metabolic process +is_a: GO:0045493 ! xylan catabolic process +created_by: jl +creation_date: 2011-07-28T09:31:50Z + +[Term] +id: GO:2000889 +name: cellodextrin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cellodextrin." [GOC:obol] +synonym: "cellodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0044042 ! glucan metabolic process +created_by: jl +creation_date: 2011-07-28T01:00:04Z + +[Term] +id: GO:2000890 +name: cellodextrin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cellodextrin." [GOC:mengo_curators] +synonym: "cellodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:2000889 ! cellodextrin metabolic process +created_by: jl +creation_date: 2011-07-28T01:05:21Z + +[Term] +id: GO:2000891 +name: cellobiose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cellobiose." [GOC:mengo_curators] +synonym: "cellobiose metabolism" EXACT [GOC:obol] +is_a: GO:0005984 ! disaccharide metabolic process +created_by: jl +creation_date: 2011-07-28T01:35:35Z + +[Term] +id: GO:2000892 +name: cellobiose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cellobiose." [GOC:mengo_curators] +synonym: "cellobiose catabolism" EXACT [GOC:obol] +is_a: GO:0046352 ! disaccharide catabolic process +is_a: GO:2000891 ! cellobiose metabolic process +created_by: jl +creation_date: 2011-07-28T01:35:38Z + +[Term] +id: GO:2000893 +name: cellotriose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cellotriose." [GOC:mengo_curators] +synonym: "cellotriose metabolism" EXACT [GOC:obol] +is_a: GO:0009311 ! oligosaccharide metabolic process +created_by: jl +creation_date: 2011-07-28T02:02:44Z + +[Term] +id: GO:2000894 +name: cellotriose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cellotriose." [GOC:mengo_curators] +synonym: "cellotriose catabolism" EXACT [GOC:obol] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:2000893 ! cellotriose metabolic process +created_by: jl +creation_date: 2011-07-28T02:02:47Z + +[Term] +id: GO:2000895 +name: hemicellulose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a hemicellulose." [GOC:mengo_curators] +synonym: "hemicellulose catabolism" EXACT [GOC:obol] +is_a: GO:0010410 ! hemicellulose metabolic process +is_a: GO:0044347 ! cell wall polysaccharide catabolic process +created_by: jl +creation_date: 2011-07-28T02:08:11Z + +[Term] +id: GO:2000896 +name: amylopectin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving an amylopectin." [GOC:mengo_curators] +synonym: "Amylopectin metabolism" EXACT [GOC:obol] +is_a: GO:0043170 ! macromolecule metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: jl +creation_date: 2011-07-28T02:47:25Z + +[Term] +id: GO:2000897 +name: amylopectin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of an amylopectin." [GOC:mengo_curators] +synonym: "Amylopectin catabolism" EXACT [GOC:obol] +is_a: GO:0009057 ! macromolecule catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:2000896 ! amylopectin metabolic process +created_by: jl +creation_date: 2011-07-28T02:47:28Z + +[Term] +id: GO:2000898 +name: regulation of glucomannan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucomannan catabolic process." [GOC:mengo_curators] +synonym: "regulation of glucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000884 ! glucomannan catabolic process +relationship: regulates GO:2000884 ! glucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T01:13:16Z + +[Term] +id: GO:2000899 +name: xyloglucan catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a xyloglucan." [GOC:mengo_curators] +synonym: "xyloglucan catabolism" EXACT [GOC:obol] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0010411 ! xyloglucan metabolic process +is_a: GO:2000895 ! hemicellulose catabolic process +created_by: jl +creation_date: 2011-07-28T02:52:33Z + +[Term] +id: GO:2000900 +name: cyclodextrin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cyclodextrin." [GOC:mengo_curators] +synonym: "cyclodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0009311 ! oligosaccharide metabolic process +is_a: GO:0044042 ! glucan metabolic process +created_by: jl +creation_date: 2011-07-28T03:19:11Z + +[Term] +id: GO:2000901 +name: cyclodextrin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cyclodextrin." [GOC:mengo_curators] +synonym: "cyclodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009251 ! glucan catabolic process +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:2000900 ! cyclodextrin metabolic process +created_by: jl +creation_date: 2011-07-28T03:19:13Z + +[Term] +id: GO:2000902 +name: cellooligosaccharide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a cellooligosaccharide." [GOC:mengo_curators] +synonym: "cellooligosaccharide metabolism" EXACT [GOC:obol] +is_a: GO:0009311 ! oligosaccharide metabolic process +created_by: jl +creation_date: 2011-07-28T03:21:46Z + +[Term] +id: GO:2000903 +name: cellooligosaccharide catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide." [GOC:mengo_curators] +synonym: "cellooligosaccharide catabolism" EXACT [GOC:obol] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:2000902 ! cellooligosaccharide metabolic process +created_by: jl +creation_date: 2011-07-28T03:21:49Z + +[Term] +id: GO:2000904 +name: regulation of starch metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of starch metabolic process." [GOC:obol] +synonym: "regulation of starch metabolism" EXACT [GOC:obol] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005982 ! starch metabolic process +relationship: regulates GO:0005982 ! starch metabolic process +created_by: tb +creation_date: 2011-07-28T11:33:13Z + +[Term] +id: GO:2000905 +name: negative regulation of starch metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process." [GOC:obol] +synonym: "negative regulation of starch metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000904 ! regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005982 ! starch metabolic process +relationship: negatively_regulates GO:0005982 ! starch metabolic process +created_by: tb +creation_date: 2011-07-28T11:33:17Z + +[Term] +id: GO:2000906 +name: positive regulation of starch metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of starch metabolic process." [GOC:obol] +synonym: "positive regulation of starch metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:2000904 ! regulation of starch metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005982 ! starch metabolic process +relationship: positively_regulates GO:0005982 ! starch metabolic process +created_by: tb +creation_date: 2011-07-28T11:33:19Z + +[Term] +id: GO:2000907 +name: negative regulation of glucomannan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of glucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000898 ! regulation of glucomannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000884 ! glucomannan catabolic process +relationship: negatively_regulates GO:2000884 ! glucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T01:13:24Z + +[Term] +id: GO:2000908 +name: positive regulation of glucomannan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of glucomannan catabolism" EXACT [GOC:obol] +is_a: GO:2000898 ! regulation of glucomannan catabolic process +is_a: GO:2000996 ! positive regulation of mannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000884 ! glucomannan catabolic process +relationship: positively_regulates GO:2000884 ! glucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T01:13:30Z + +[Term] +id: GO:2000909 +name: regulation of sterol import +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of sterol import." [GOC:obol] +synonym: "regulation of sterol influx" EXACT [GOC:obol] +synonym: "regulation of sterol uptake" EXACT [GOC:obol] +is_a: GO:0032371 ! regulation of sterol transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035376 ! sterol import +relationship: regulates GO:0035376 ! sterol import +created_by: bf +creation_date: 2011-07-29T01:25:10Z + +[Term] +id: GO:2000910 +name: negative regulation of sterol import +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of sterol import." [GOC:obol] +synonym: "negative regulation of sterol influx" EXACT [GOC:obol] +synonym: "negative regulation of sterol uptake" EXACT [GOC:obol] +is_a: GO:0032372 ! negative regulation of sterol transport +is_a: GO:2000909 ! regulation of sterol import +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035376 ! sterol import +relationship: negatively_regulates GO:0035376 ! sterol import +created_by: bf +creation_date: 2011-07-29T01:25:14Z + +[Term] +id: GO:2000911 +name: positive regulation of sterol import +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of sterol import." [GOC:obol] +synonym: "positive regulation of sterol influx" EXACT [GOC:obol] +synonym: "positive regulation of sterol uptake" EXACT [GOC:obol] +is_a: GO:0032373 ! positive regulation of sterol transport +is_a: GO:2000909 ! regulation of sterol import +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035376 ! sterol import +relationship: positively_regulates GO:0035376 ! sterol import +created_by: bf +creation_date: 2011-07-29T01:25:17Z + +[Term] +id: GO:2000912 +name: regulation of galactoglucomannan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process." [GOC:mengo_curators] +synonym: "regulation of galactoglucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000885 ! galactoglucomannan catabolic process +relationship: regulates GO:2000885 ! galactoglucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T07:51:31Z + +[Term] +id: GO:2000913 +name: negative regulation of galactoglucomannan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of galactoglucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000912 ! regulation of galactoglucomannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000885 ! galactoglucomannan catabolic process +relationship: negatively_regulates GO:2000885 ! galactoglucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T07:51:41Z + +[Term] +id: GO:2000914 +name: positive regulation of galactoglucomannan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of galactoglucomannan catabolism" EXACT [GOC:obol] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000912 ! regulation of galactoglucomannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000885 ! galactoglucomannan catabolic process +relationship: positively_regulates GO:2000885 ! galactoglucomannan catabolic process +created_by: tt +creation_date: 2011-07-29T07:51:50Z + +[Term] +id: GO:2000915 +name: regulation of glucuronoxylan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process." [GOC:mengo_curators] +synonym: "regulation of glucuronoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2001000 ! regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000886 ! glucuronoxylan catabolic process +relationship: regulates GO:2000886 ! glucuronoxylan catabolic process +created_by: tt +creation_date: 2011-07-29T07:54:35Z + +[Term] +id: GO:2000916 +name: negative regulation of glucuronoxylan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of glucuronoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000915 ! regulation of glucuronoxylan catabolic process +is_a: GO:2001001 ! negative regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000886 ! glucuronoxylan catabolic process +relationship: negatively_regulates GO:2000886 ! glucuronoxylan catabolic process +created_by: tt +creation_date: 2011-07-29T07:54:44Z + +[Term] +id: GO:2000917 +name: positive regulation of glucuronoxylan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of glucuronoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000915 ! regulation of glucuronoxylan catabolic process +is_a: GO:2001002 ! positive regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000886 ! glucuronoxylan catabolic process +relationship: positively_regulates GO:2000886 ! glucuronoxylan catabolic process +created_by: tt +creation_date: 2011-07-29T07:54:50Z + +[Term] +id: GO:2000918 +name: regulation of glucuronoarabinoxylan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process." [GOC:mengo_curators] +synonym: "regulation of glucuronoarabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000915 ! regulation of glucuronoxylan catabolic process +is_a: GO:2000921 ! regulation of arabinoxylan-containing compound catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +relationship: regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +created_by: tt +creation_date: 2011-08-01T12:36:47Z + +[Term] +id: GO:2000919 +name: negative regulation of glucuronoarabinoxylan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of glucuronoarabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000916 ! negative regulation of glucuronoxylan catabolic process +is_a: GO:2000918 ! regulation of glucuronoarabinoxylan catabolic process +is_a: GO:2000922 ! negative regulation of arabinoxylan-containing compound catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +relationship: negatively_regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +created_by: tt +creation_date: 2011-08-01T12:36:53Z + +[Term] +id: GO:2000920 +name: positive regulation of glucuronoarabinoxylan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of glucuronoarabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000917 ! positive regulation of glucuronoxylan catabolic process +is_a: GO:2000918 ! regulation of glucuronoarabinoxylan catabolic process +is_a: GO:2000923 ! positive regulation of arabinoxylan-containing compound catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +relationship: positively_regulates GO:2000887 ! glucuronoarabinoxylan catabolic process +created_by: tt +creation_date: 2011-08-01T12:36:58Z + +[Term] +id: GO:2000921 +name: regulation of arabinoxylan-containing compound catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process." [GOC:mengo_curators] +synonym: "regulation of arabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2001000 ! regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +relationship: regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +created_by: tt +creation_date: 2011-08-01T12:38:56Z + +[Term] +id: GO:2000922 +name: negative regulation of arabinoxylan-containing compound catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of arabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000921 ! regulation of arabinoxylan-containing compound catabolic process +is_a: GO:2001001 ! negative regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +relationship: negatively_regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +created_by: tt +creation_date: 2011-08-01T12:39:00Z + +[Term] +id: GO:2000923 +name: positive regulation of arabinoxylan-containing compound catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of arabinoxylan catabolism" EXACT [GOC:obol] +is_a: GO:2000921 ! regulation of arabinoxylan-containing compound catabolic process +is_a: GO:2001002 ! positive regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +relationship: positively_regulates GO:2000888 ! arabinoxylan-containing compound catabolic process +created_by: tt +creation_date: 2011-08-01T12:39:02Z + +[Term] +id: GO:2000924 +name: regulation of cellodextrin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellodextrin metabolic process." [GOC:mengo_curators] +synonym: "regulation of cellodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000889 ! cellodextrin metabolic process +relationship: regulates GO:2000889 ! cellodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T12:39:52Z + +[Term] +id: GO:2000925 +name: negative regulation of cellodextrin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000924 ! regulation of cellodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000889 ! cellodextrin metabolic process +relationship: negatively_regulates GO:2000889 ! cellodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T12:39:56Z + +[Term] +id: GO:2000926 +name: positive regulation of cellodextrin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000924 ! regulation of cellodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000889 ! cellodextrin metabolic process +relationship: positively_regulates GO:2000889 ! cellodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T12:39:59Z + +[Term] +id: GO:2000927 +name: regulation of cellodextrin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellodextrin catabolic process." [GOC:mengo_curators] +synonym: "regulation of cellodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:2000924 ! regulation of cellodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000890 ! cellodextrin catabolic process +relationship: regulates GO:2000890 ! cellodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T12:41:29Z + +[Term] +id: GO:2000928 +name: negative regulation of cellodextrin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:2000925 ! negative regulation of cellodextrin metabolic process +is_a: GO:2000927 ! regulation of cellodextrin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000890 ! cellodextrin catabolic process +relationship: negatively_regulates GO:2000890 ! cellodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T12:41:33Z + +[Term] +id: GO:2000929 +name: positive regulation of cellodextrin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:2000926 ! positive regulation of cellodextrin metabolic process +is_a: GO:2000927 ! regulation of cellodextrin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000890 ! cellodextrin catabolic process +relationship: positively_regulates GO:2000890 ! cellodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T12:41:36Z + +[Term] +id: GO:2000930 +name: regulation of cellobiose metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellobiose metabolic process." [GOC:mengo_curators] +synonym: "regulation of cellobiose metabolism" EXACT [GOC:obol] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000891 ! cellobiose metabolic process +relationship: regulates GO:2000891 ! cellobiose metabolic process +created_by: tt +creation_date: 2011-08-01T12:42:53Z + +[Term] +id: GO:2000931 +name: negative regulation of cellobiose metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellobiose metabolism" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000930 ! regulation of cellobiose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000891 ! cellobiose metabolic process +relationship: negatively_regulates GO:2000891 ! cellobiose metabolic process +created_by: tt +creation_date: 2011-08-01T12:42:57Z + +[Term] +id: GO:2000932 +name: positive regulation of cellobiose metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellobiose metabolism" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:2000930 ! regulation of cellobiose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000891 ! cellobiose metabolic process +relationship: positively_regulates GO:2000891 ! cellobiose metabolic process +created_by: tt +creation_date: 2011-08-01T12:43:01Z + +[Term] +id: GO:2000933 +name: regulation of cellotriose metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellotriose metabolic process." [GOC:mengo_curators] +synonym: "regulation of cellotriose metabolism" EXACT [GOC:obol] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000893 ! cellotriose metabolic process +relationship: regulates GO:2000893 ! cellotriose metabolic process +created_by: tt +creation_date: 2011-08-01T12:44:15Z + +[Term] +id: GO:2000934 +name: negative regulation of cellotriose metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellotriose metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000933 ! regulation of cellotriose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000893 ! cellotriose metabolic process +relationship: negatively_regulates GO:2000893 ! cellotriose metabolic process +created_by: tt +creation_date: 2011-08-01T12:44:20Z + +[Term] +id: GO:2000935 +name: positive regulation of cellotriose metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellotriose metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000933 ! regulation of cellotriose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000893 ! cellotriose metabolic process +relationship: positively_regulates GO:2000893 ! cellotriose metabolic process +created_by: tt +creation_date: 2011-08-01T12:44:24Z + +[Term] +id: GO:2000936 +name: regulation of cellotriose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellotriose catabolic process." [GOC:mengo_curators] +synonym: "regulation of cellotriose catabolism" EXACT [GOC:obol] +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:2000933 ! regulation of cellotriose metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000894 ! cellotriose catabolic process +relationship: regulates GO:2000894 ! cellotriose catabolic process +created_by: tt +creation_date: 2011-08-01T12:45:26Z + +[Term] +id: GO:2000937 +name: negative regulation of cellotriose catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellotriose catabolism" EXACT [GOC:obol] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:2000934 ! negative regulation of cellotriose metabolic process +is_a: GO:2000936 ! regulation of cellotriose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000894 ! cellotriose catabolic process +relationship: negatively_regulates GO:2000894 ! cellotriose catabolic process +created_by: tt +creation_date: 2011-08-01T12:45:31Z + +[Term] +id: GO:2000938 +name: positive regulation of cellotriose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellotriose catabolism" EXACT [GOC:obol] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:2000935 ! positive regulation of cellotriose metabolic process +is_a: GO:2000936 ! regulation of cellotriose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000894 ! cellotriose catabolic process +relationship: positively_regulates GO:2000894 ! cellotriose catabolic process +created_by: tt +creation_date: 2011-08-01T12:45:35Z + +[Term] +id: GO:2000939 +name: regulation of plant-type cell wall cellulose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process." [GOC:mengo_curators] +synonym: "regulation of plant-type cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0032950 ! regulation of beta-glucan metabolic process +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +relationship: regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +created_by: tt +creation_date: 2011-08-01T02:07:11Z + +[Term] +id: GO:2000940 +name: negative regulation of plant-type cell wall cellulose catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of plant-type cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:2000939 ! regulation of plant-type cell wall cellulose catabolic process +is_a: GO:2000967 ! negative regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +relationship: negatively_regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +created_by: tt +creation_date: 2011-08-01T02:07:17Z + +[Term] +id: GO:2000941 +name: positive regulation of plant-type cell wall cellulose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of plant-type cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:2000939 ! regulation of plant-type cell wall cellulose catabolic process +is_a: GO:2000968 ! positive regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +relationship: positively_regulates GO:0044348 ! plant-type cell wall cellulose catabolic process +created_by: tt +creation_date: 2011-08-01T02:07:21Z + +[Term] +id: GO:2000942 +name: regulation of amylopectin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amylopectin metabolic process." [GOC:mengo_curators] +synonym: "regulation of Amylopectin metabolism" EXACT [GOC:obol] +is_a: GO:0031323 ! regulation of cellular metabolic process +is_a: GO:0060255 ! regulation of macromolecule metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000896 ! amylopectin metabolic process +relationship: regulates GO:2000896 ! amylopectin metabolic process +created_by: tt +creation_date: 2011-08-01T02:10:28Z + +[Term] +id: GO:2000943 +name: negative regulation of amylopectin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of Amylopectin metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process +is_a: GO:2000942 ! regulation of amylopectin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000896 ! amylopectin metabolic process +relationship: negatively_regulates GO:2000896 ! amylopectin metabolic process +created_by: tt +creation_date: 2011-08-01T02:10:32Z + +[Term] +id: GO:2000944 +name: positive regulation of amylopectin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of Amylopectin metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:2000942 ! regulation of amylopectin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000896 ! amylopectin metabolic process +relationship: positively_regulates GO:2000896 ! amylopectin metabolic process +created_by: tt +creation_date: 2011-08-01T02:10:36Z + +[Term] +id: GO:2000945 +name: regulation of amylopectin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of amylopectin catabolic process." [GOC:mengo_curators] +synonym: "regulation of Amylopectin catabolism" EXACT [GOC:obol] +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:2000942 ! regulation of amylopectin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000897 ! amylopectin catabolic process +relationship: regulates GO:2000897 ! amylopectin catabolic process +created_by: tt +creation_date: 2011-08-01T02:15:22Z + +[Term] +id: GO:2000946 +name: negative regulation of amylopectin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of Amylopectin catabolism" EXACT [GOC:obol] +is_a: GO:2000882 ! negative regulation of starch catabolic process +is_a: GO:2000943 ! negative regulation of amylopectin metabolic process +is_a: GO:2000945 ! regulation of amylopectin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000897 ! amylopectin catabolic process +relationship: negatively_regulates GO:2000897 ! amylopectin catabolic process +created_by: tt +creation_date: 2011-08-01T02:15:27Z + +[Term] +id: GO:2000947 +name: positive regulation of amylopectin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of Amylopectin catabolism" EXACT [GOC:obol] +is_a: GO:2000883 ! positive regulation of starch catabolic process +is_a: GO:2000944 ! positive regulation of amylopectin metabolic process +is_a: GO:2000945 ! regulation of amylopectin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000897 ! amylopectin catabolic process +relationship: positively_regulates GO:2000897 ! amylopectin catabolic process +created_by: tt +creation_date: 2011-08-01T02:15:32Z + +[Term] +id: GO:2000948 +name: regulation of xyloglucan metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xyloglucan metabolic process." [GOC:mengo_curators] +synonym: "regulation of xyloglucan metabolism" EXACT [GOC:obol] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010411 ! xyloglucan metabolic process +relationship: regulates GO:0010411 ! xyloglucan metabolic process +created_by: tt +creation_date: 2011-08-01T02:16:54Z + +[Term] +id: GO:2000949 +name: negative regulation of xyloglucan metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of xyloglucan metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:1903339 ! negative regulation of cell wall organization or biogenesis +is_a: GO:2000948 ! regulation of xyloglucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010411 ! xyloglucan metabolic process +relationship: negatively_regulates GO:0010411 ! xyloglucan metabolic process +created_by: tt +creation_date: 2011-08-01T02:16:59Z + +[Term] +id: GO:2000950 +name: positive regulation of xyloglucan metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of xyloglucan metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:1903340 ! positive regulation of cell wall organization or biogenesis +is_a: GO:2000948 ! regulation of xyloglucan metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010411 ! xyloglucan metabolic process +relationship: positively_regulates GO:0010411 ! xyloglucan metabolic process +created_by: tt +creation_date: 2011-08-01T02:17:02Z + +[Term] +id: GO:2000951 +name: regulation of xyloglucan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xyloglucan catabolic process." [GOC:mengo_curators] +synonym: "regulation of xyloglucan catabolism" EXACT [GOC:obol] +is_a: GO:2000948 ! regulation of xyloglucan metabolic process +is_a: GO:2000988 ! regulation of hemicellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000899 ! xyloglucan catabolic process +relationship: regulates GO:2000899 ! xyloglucan catabolic process +created_by: tt +creation_date: 2011-08-01T02:20:16Z + +[Term] +id: GO:2000952 +name: negative regulation of xyloglucan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of xyloglucan catabolism" EXACT [GOC:obol] +is_a: GO:2000949 ! negative regulation of xyloglucan metabolic process +is_a: GO:2000951 ! regulation of xyloglucan catabolic process +is_a: GO:2000989 ! negative regulation of hemicellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000899 ! xyloglucan catabolic process +relationship: negatively_regulates GO:2000899 ! xyloglucan catabolic process +created_by: tt +creation_date: 2011-08-01T02:20:21Z + +[Term] +id: GO:2000953 +name: positive regulation of xyloglucan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of xyloglucan catabolism" EXACT [GOC:obol] +is_a: GO:2000950 ! positive regulation of xyloglucan metabolic process +is_a: GO:2000951 ! regulation of xyloglucan catabolic process +is_a: GO:2000990 ! positive regulation of hemicellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000899 ! xyloglucan catabolic process +relationship: positively_regulates GO:2000899 ! xyloglucan catabolic process +created_by: tt +creation_date: 2011-08-01T02:20:26Z + +[Term] +id: GO:2000954 +name: regulation of cyclodextrin metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process." [GOC:mengo_curators] +synonym: "regulation of cyclodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000900 ! cyclodextrin metabolic process +relationship: regulates GO:2000900 ! cyclodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T02:22:00Z + +[Term] +id: GO:2000955 +name: negative regulation of cyclodextrin metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cyclodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000954 ! regulation of cyclodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000900 ! cyclodextrin metabolic process +relationship: negatively_regulates GO:2000900 ! cyclodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T02:22:05Z + +[Term] +id: GO:2000956 +name: positive regulation of cyclodextrin metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cyclodextrin metabolism" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000954 ! regulation of cyclodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000900 ! cyclodextrin metabolic process +relationship: positively_regulates GO:2000900 ! cyclodextrin metabolic process +created_by: tt +creation_date: 2011-08-01T02:22:09Z + +[Term] +id: GO:2000957 +name: regulation of cyclodextrin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process." [GOC:mengo_curators] +synonym: "regulation of cyclodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:2000954 ! regulation of cyclodextrin metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000901 ! cyclodextrin catabolic process +relationship: regulates GO:2000901 ! cyclodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T02:23:55Z + +[Term] +id: GO:2000958 +name: negative regulation of cyclodextrin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cyclodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:2000955 ! negative regulation of cyclodextrin metabolic process +is_a: GO:2000957 ! regulation of cyclodextrin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000901 ! cyclodextrin catabolic process +relationship: negatively_regulates GO:2000901 ! cyclodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T02:24:02Z + +[Term] +id: GO:2000959 +name: positive regulation of cyclodextrin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cyclodextrin catabolism" EXACT [GOC:obol] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:2000956 ! positive regulation of cyclodextrin metabolic process +is_a: GO:2000957 ! regulation of cyclodextrin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000901 ! cyclodextrin catabolic process +relationship: positively_regulates GO:2000901 ! cyclodextrin catabolic process +created_by: tt +creation_date: 2011-08-01T02:24:06Z + +[Term] +id: GO:2000960 +name: regulation of cellooligosaccharide metabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process." [GOC:mengo_curators] +synonym: "regulation of cellooligosaccharide metabolism" EXACT [GOC:obol] +is_a: GO:0006109 ! regulation of carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000902 ! cellooligosaccharide metabolic process +relationship: regulates GO:2000902 ! cellooligosaccharide metabolic process +created_by: tt +creation_date: 2011-08-01T02:25:54Z + +[Term] +id: GO:2000961 +name: negative regulation of cellooligosaccharide metabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellooligosaccharide metabolism" EXACT [GOC:obol] +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000960 ! regulation of cellooligosaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000902 ! cellooligosaccharide metabolic process +relationship: negatively_regulates GO:2000902 ! cellooligosaccharide metabolic process +created_by: tt +creation_date: 2011-08-01T02:25:59Z + +[Term] +id: GO:2000962 +name: positive regulation of cellooligosaccharide metabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellooligosaccharide metabolism" EXACT [GOC:obol] +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000960 ! regulation of cellooligosaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000902 ! cellooligosaccharide metabolic process +relationship: positively_regulates GO:2000902 ! cellooligosaccharide metabolic process +created_by: tt +creation_date: 2011-08-01T02:26:02Z + +[Term] +id: GO:2000963 +name: regulation of cellooligosaccharide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process." [GOC:mengo_curators] +synonym: "regulation of cellooligosaccharide catabolism" EXACT [GOC:obol] +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +is_a: GO:2000960 ! regulation of cellooligosaccharide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000903 ! cellooligosaccharide catabolic process +relationship: regulates GO:2000903 ! cellooligosaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:28:36Z + +[Term] +id: GO:2000964 +name: negative regulation of cellooligosaccharide catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellooligosaccharide catabolism" EXACT [GOC:obol] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:2000961 ! negative regulation of cellooligosaccharide metabolic process +is_a: GO:2000963 ! regulation of cellooligosaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000903 ! cellooligosaccharide catabolic process +relationship: negatively_regulates GO:2000903 ! cellooligosaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:28:42Z + +[Term] +id: GO:2000965 +name: positive regulation of cellooligosaccharide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellooligosaccharide catabolism" EXACT [GOC:obol] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:2000962 ! positive regulation of cellooligosaccharide metabolic process +is_a: GO:2000963 ! regulation of cellooligosaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000903 ! cellooligosaccharide catabolic process +relationship: positively_regulates GO:2000903 ! cellooligosaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:28:47Z + +[Term] +id: GO:2000966 +name: regulation of cell wall polysaccharide catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process." [GOC:mengo_curators] +synonym: "regulation of cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0031329 ! regulation of cellular catabolic process +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0044347 ! cell wall polysaccharide catabolic process +relationship: regulates GO:0044347 ! cell wall polysaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:30:27Z + +[Term] +id: GO:2000967 +name: negative regulation of cell wall polysaccharide catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:1903339 ! negative regulation of cell wall organization or biogenesis +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0044347 ! cell wall polysaccharide catabolic process +relationship: negatively_regulates GO:0044347 ! cell wall polysaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:30:33Z + +[Term] +id: GO:2000968 +name: positive regulation of cell wall polysaccharide catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cell wall polysaccharide breakdown" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:1903340 ! positive regulation of cell wall organization or biogenesis +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0044347 ! cell wall polysaccharide catabolic process +relationship: positively_regulates GO:0044347 ! cell wall polysaccharide catabolic process +created_by: tt +creation_date: 2011-08-01T02:30:37Z + +[Term] +id: GO:2000969 +name: positive regulation of AMPA receptor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity." [PMID:21423165] +synonym: "positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity" BROAD [] +is_a: GO:1900451 ! positive regulation of glutamate receptor signaling pathway +is_a: GO:2000273 ! positive regulation of signaling receptor activity +is_a: GO:2000311 ! regulation of AMPA receptor activity +is_a: GO:2001259 ! positive regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004971 ! AMPA glutamate receptor activity +relationship: positively_regulates GO:0004971 ! AMPA glutamate receptor activity +created_by: pr +creation_date: 2011-08-03T10:27:08Z + +[Term] +id: GO:2000970 +name: regulation of detection of glucose +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of detection of glucose." [GOC:BHF] +synonym: "regulation of glucose detection" EXACT [GOC:obol] +synonym: "regulation of glucose perception" RELATED [GOC:obol] +synonym: "regulation of glucose sensing" RELATED [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051594 ! detection of glucose +relationship: regulates GO:0051594 ! detection of glucose +created_by: vk +creation_date: 2011-08-02T10:18:52Z + +[Term] +id: GO:2000971 +name: negative regulation of detection of glucose +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose." [GOC:BHF] +synonym: "negative regulation of glucose detection" EXACT [GOC:obol] +synonym: "negative regulation of glucose perception" RELATED [GOC:obol] +synonym: "negative regulation of glucose sensing" RELATED [GOC:obol] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2000970 ! regulation of detection of glucose +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051594 ! detection of glucose +relationship: negatively_regulates GO:0051594 ! detection of glucose +created_by: vk +creation_date: 2011-08-02T10:18:54Z + +[Term] +id: GO:2000972 +name: positive regulation of detection of glucose +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of detection of glucose." [GOC:BHF] +synonym: "positive regulation of glucose detection" EXACT [GOC:obol] +synonym: "positive regulation of glucose perception" RELATED [GOC:obol] +synonym: "positive regulation of glucose sensing" RELATED [GOC:obol] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2000970 ! regulation of detection of glucose +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051594 ! detection of glucose +relationship: positively_regulates GO:0051594 ! detection of glucose +created_by: vk +creation_date: 2011-08-02T10:18:56Z + +[Term] +id: GO:2000973 +name: regulation of pro-B cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pro-B cell differentiation." [GOC:obol] +synonym: "regulation of pro-B cell development" RELATED [GOC:obol] +synonym: "regulation of pro-B lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002328 ! pro-B cell differentiation +relationship: regulates GO:0002328 ! pro-B cell differentiation +created_by: yaf +creation_date: 2011-08-02T03:05:45Z + +[Term] +id: GO:2000974 +name: negative regulation of pro-B cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation." [GOC:obol] +synonym: "negative regulation of pro-B cell development" RELATED [GOC:obol] +synonym: "negative regulation of pro-B lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation +is_a: GO:2000973 ! regulation of pro-B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002328 ! pro-B cell differentiation +relationship: negatively_regulates GO:0002328 ! pro-B cell differentiation +created_by: yaf +creation_date: 2011-08-02T03:05:50Z + +[Term] +id: GO:2000975 +name: positive regulation of pro-B cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation." [GOC:obol] +synonym: "positive regulation of pro-B cell development" RELATED [GOC:obol] +synonym: "positive regulation of pro-B lymphocyte differentiation" EXACT [GOC:obol] +is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation +is_a: GO:2000973 ! regulation of pro-B cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002328 ! pro-B cell differentiation +relationship: positively_regulates GO:0002328 ! pro-B cell differentiation +created_by: yaf +creation_date: 2011-08-02T03:05:53Z + +[Term] +id: GO:2000976 +name: obsolete regulation of transcription from RNA polymerase II promoter involved in detection of glucose +namespace: biological_process +def: "OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in detection of glucose." [GOC:BHF] +comment: This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization. +synonym: "global transcription regulation from Pol II promoter involved in detection of glucose" RELATED [GOC:obol] +synonym: "global transcription regulation from Pol II promoter involved in glucose detection" RELATED [GOC:obol] +synonym: "global transcription regulation from Pol II promoter involved in glucose perception" RELATED [GOC:obol] +synonym: "global transcription regulation from Pol II promoter involved in glucose sensing" RELATED [GOC:obol] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in detection of glucose" RELATED [GOC:obol] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose detection" RELATED [GOC:obol] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose perception" RELATED [GOC:obol] +synonym: "regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose sensing" RELATED [GOC:obol] +synonym: "regulation of global transcription from Pol II promoter involved in detection of glucose" RELATED [GOC:obol] +synonym: "regulation of global transcription from Pol II promoter involved in glucose detection" RELATED [GOC:obol] +synonym: "regulation of global transcription from Pol II promoter involved in glucose perception" RELATED [GOC:obol] +synonym: "regulation of global transcription from Pol II promoter involved in glucose sensing" RELATED [GOC:obol] +synonym: "regulation of transcription from Pol II promoter involved in detection of glucose" EXACT [GOC:obol] +synonym: "regulation of transcription from Pol II promoter involved in glucose detection" EXACT [GOC:obol] +synonym: "regulation of transcription from Pol II promoter involved in glucose perception" RELATED [GOC:obol] +synonym: "regulation of transcription from Pol II promoter involved in glucose sensing" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter involved in glucose detection" EXACT [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter involved in glucose perception" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter involved in glucose sensing" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in detection of glucose" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in glucose detection" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in glucose perception" RELATED [GOC:obol] +synonym: "regulation of transcription from RNA polymerase II promoter, global involved in glucose sensing" RELATED [GOC:obol] +is_obsolete: true +consider: GO:0051594 +created_by: vk +creation_date: 2011-08-02T05:06:52Z + +[Term] +id: GO:2000977 +name: regulation of forebrain neuron differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] +is_a: GO:0045664 ! regulation of neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0021879 ! forebrain neuron differentiation +relationship: regulates GO:0021879 ! forebrain neuron differentiation +created_by: yaf +creation_date: 2011-08-03T12:09:12Z + +[Term] +id: GO:2000978 +name: negative regulation of forebrain neuron differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] +is_a: GO:0045665 ! negative regulation of neuron differentiation +is_a: GO:2000977 ! regulation of forebrain neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0021879 ! forebrain neuron differentiation +relationship: negatively_regulates GO:0021879 ! forebrain neuron differentiation +created_by: yaf +creation_date: 2011-08-03T12:09:16Z + +[Term] +id: GO:2000979 +name: positive regulation of forebrain neuron differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] +is_a: GO:0045666 ! positive regulation of neuron differentiation +is_a: GO:2000977 ! regulation of forebrain neuron differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0021879 ! forebrain neuron differentiation +relationship: positively_regulates GO:0021879 ! forebrain neuron differentiation +created_by: yaf +creation_date: 2011-08-03T12:09:19Z + +[Term] +id: GO:2000980 +name: regulation of inner ear receptor cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation." [GOC:obol] +synonym: "regulation of inner ear hair cell differentiation" EXACT [GOC:obol] +is_a: GO:0045631 ! regulation of mechanoreceptor differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0060113 ! inner ear receptor cell differentiation +relationship: regulates GO:0060113 ! inner ear receptor cell differentiation +created_by: yaf +creation_date: 2011-08-03T02:38:43Z + +[Term] +id: GO:2000981 +name: negative regulation of inner ear receptor cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation." [GOC:obol] +synonym: "negative regulation of inner ear hair cell differentiation" EXACT [GOC:obol] +is_a: GO:0045632 ! negative regulation of mechanoreceptor differentiation +is_a: GO:2000980 ! regulation of inner ear receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0060113 ! inner ear receptor cell differentiation +relationship: negatively_regulates GO:0060113 ! inner ear receptor cell differentiation +created_by: yaf +creation_date: 2011-08-03T02:38:47Z + +[Term] +id: GO:2000982 +name: positive regulation of inner ear receptor cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation." [GOC:obol] +synonym: "positive regulation of inner ear hair cell differentiation" EXACT [GOC:obol] +is_a: GO:0045633 ! positive regulation of mechanoreceptor differentiation +is_a: GO:2000980 ! regulation of inner ear receptor cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0060113 ! inner ear receptor cell differentiation +relationship: positively_regulates GO:0060113 ! inner ear receptor cell differentiation +created_by: yaf +creation_date: 2011-08-03T02:38:51Z + +[Term] +id: GO:2000983 +name: regulation of ATP citrate synthase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] +synonym: "regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] +synonym: "regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] +synonym: "regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] +synonym: "regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] +synonym: "regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] +synonym: "regulation of ATP-citric lyase activity" EXACT [GOC:obol] +synonym: "regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] +synonym: "regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] +synonym: "regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] +synonym: "regulation of citrate-ATP lyase activity" EXACT [GOC:obol] +synonym: "regulation of citric cleavage enzyme activity" RELATED [GOC:obol] +is_a: GO:0051338 ! regulation of transferase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003878 ! ATP citrate synthase activity +relationship: regulates GO:0003878 ! ATP citrate synthase activity +created_by: vk +creation_date: 2011-08-04T03:15:24Z + +[Term] +id: GO:2000984 +name: negative regulation of ATP citrate synthase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] +synonym: "negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] +synonym: "negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] +synonym: "negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] +synonym: "negative regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP-citric lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] +synonym: "negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] +synonym: "negative regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] +synonym: "negative regulation of citrate-ATP lyase activity" EXACT [GOC:obol] +synonym: "negative regulation of citric cleavage enzyme activity" RELATED [GOC:obol] +is_a: GO:0051348 ! negative regulation of transferase activity +is_a: GO:2000983 ! regulation of ATP citrate synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003878 ! ATP citrate synthase activity +relationship: negatively_regulates GO:0003878 ! ATP citrate synthase activity +created_by: vk +creation_date: 2011-08-04T03:15:28Z + +[Term] +id: GO:2000985 +name: positive regulation of ATP citrate synthase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] +synonym: "positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] +synonym: "positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] +synonym: "positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] +synonym: "positive regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP-citric lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] +synonym: "positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] +synonym: "positive regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] +synonym: "positive regulation of citrate-ATP lyase activity" EXACT [GOC:obol] +synonym: "positive regulation of citric cleavage enzyme activity" RELATED [GOC:obol] +is_a: GO:0051347 ! positive regulation of transferase activity +is_a: GO:2000983 ! regulation of ATP citrate synthase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003878 ! ATP citrate synthase activity +relationship: positively_regulates GO:0003878 ! ATP citrate synthase activity +created_by: vk +creation_date: 2011-08-04T03:15:31Z + +[Term] +id: GO:2000986 +name: negative regulation of behavioral fear response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response." [GOC:obol] +synonym: "negative regulation of behavioural fear response" EXACT [GOC:obol] +is_a: GO:0031348 ! negative regulation of defense response +is_a: GO:0048521 ! negative regulation of behavior +is_a: GO:1903366 ! negative regulation of fear response +is_a: GO:2000822 ! regulation of behavioral fear response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001662 ! behavioral fear response +relationship: negatively_regulates GO:0001662 ! behavioral fear response +created_by: yaf +creation_date: 2011-08-08T09:16:34Z + +[Term] +id: GO:2000987 +name: positive regulation of behavioral fear response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of behavioral fear response." [GOC:obol] +synonym: "positive regulation of behavioural fear response" EXACT [GOC:obol] +is_a: GO:0031349 ! positive regulation of defense response +is_a: GO:0048520 ! positive regulation of behavior +is_a: GO:1903367 ! positive regulation of fear response +is_a: GO:2000822 ! regulation of behavioral fear response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001662 ! behavioral fear response +relationship: positively_regulates GO:0001662 ! behavioral fear response +created_by: yaf +creation_date: 2011-08-08T09:16:39Z + +[Term] +id: GO:2000988 +name: regulation of hemicellulose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hemicellulose catabolic process." [GOC:mengo_curators] +synonym: "regulation of hemicellulose catabolism" EXACT [GOC:obol] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:2000895 ! hemicellulose catabolic process +relationship: regulates GO:2000895 ! hemicellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:08:16Z + +[Term] +id: GO:2000989 +name: negative regulation of hemicellulose catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of hemicellulose catabolism" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000967 ! negative regulation of cell wall polysaccharide catabolic process +is_a: GO:2000988 ! regulation of hemicellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:2000895 ! hemicellulose catabolic process +relationship: negatively_regulates GO:2000895 ! hemicellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:08:20Z + +[Term] +id: GO:2000990 +name: positive regulation of hemicellulose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of hemicellulose catabolism" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:2000968 ! positive regulation of cell wall polysaccharide catabolic process +is_a: GO:2000988 ! regulation of hemicellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:2000895 ! hemicellulose catabolic process +relationship: positively_regulates GO:2000895 ! hemicellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:08:23Z + +[Term] +id: GO:2000991 +name: regulation of galactomannan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of galactomannan catabolic process." [GOC:mengo_curators] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043470 ! regulation of carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051682 ! galactomannan catabolic process +relationship: regulates GO:0051682 ! galactomannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:15:53Z + +[Term] +id: GO:2000992 +name: negative regulation of galactomannan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process." [GOC:mengo_curators] +is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process +is_a: GO:2000991 ! regulation of galactomannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051682 ! galactomannan catabolic process +relationship: negatively_regulates GO:0051682 ! galactomannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:16:00Z + +[Term] +id: GO:2000993 +name: positive regulation of galactomannan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process." [GOC:mengo_curators] +is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process +is_a: GO:2000991 ! regulation of galactomannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051682 ! galactomannan catabolic process +relationship: positively_regulates GO:0051682 ! galactomannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:16:07Z + +[Term] +id: GO:2000994 +name: regulation of mannan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mannan catabolic process." [GOC:mengo_curators] +synonym: "regulation of mannan breakdown" EXACT [GOC:obol] +synonym: "regulation of mannan catabolism" EXACT [GOC:obol] +synonym: "regulation of mannan degradation" EXACT [GOC:obol] +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:2000924 ! regulation of cellodextrin metabolic process +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0046355 ! mannan catabolic process +relationship: regulates GO:0046355 ! mannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:19:03Z + +[Term] +id: GO:2000995 +name: negative regulation of mannan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of mannan breakdown" EXACT [GOC:obol] +synonym: "negative regulation of mannan catabolism" EXACT [GOC:obol] +synonym: "negative regulation of mannan degradation" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000925 ! negative regulation of cellodextrin metabolic process +is_a: GO:2000967 ! negative regulation of cell wall polysaccharide catabolic process +is_a: GO:2000994 ! regulation of mannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0046355 ! mannan catabolic process +relationship: negatively_regulates GO:0046355 ! mannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:19:11Z + +[Term] +id: GO:2000996 +name: positive regulation of mannan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mannan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of mannan breakdown" EXACT [GOC:obol] +synonym: "positive regulation of mannan catabolism" EXACT [GOC:obol] +synonym: "positive regulation of mannan degradation" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:2000926 ! positive regulation of cellodextrin metabolic process +is_a: GO:2000968 ! positive regulation of cell wall polysaccharide catabolic process +is_a: GO:2000994 ! regulation of mannan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0046355 ! mannan catabolic process +relationship: positively_regulates GO:0046355 ! mannan catabolic process +created_by: tt +creation_date: 2011-08-08T03:19:18Z + +[Term] +id: GO:2000997 +name: regulation of cellulose catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellulose catabolic process." [GOC:mengo_curators] +synonym: "regulation of cellulose breakdown" EXACT [GOC:obol] +synonym: "regulation of cellulose catabolism" EXACT [GOC:obol] +synonym: "regulation of cellulose degradation" EXACT [GOC:obol] +is_a: GO:0032950 ! regulation of beta-glucan metabolic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030245 ! cellulose catabolic process +relationship: regulates GO:0030245 ! cellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:21:20Z + +[Term] +id: GO:2000998 +name: negative regulation of cellulose catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of cellulose breakdown" EXACT [GOC:obol] +synonym: "negative regulation of cellulose catabolism" EXACT [GOC:obol] +synonym: "negative regulation of cellulose degradation" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:2000997 ! regulation of cellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030245 ! cellulose catabolic process +relationship: negatively_regulates GO:0030245 ! cellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:21:26Z + +[Term] +id: GO:2000999 +name: positive regulation of cellulose catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellulose catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of cellulose breakdown" EXACT [GOC:obol] +synonym: "positive regulation of cellulose catabolism" EXACT [GOC:obol] +synonym: "positive regulation of cellulose degradation" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2000997 ! regulation of cellulose catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030245 ! cellulose catabolic process +relationship: positively_regulates GO:0030245 ! cellulose catabolic process +created_by: tt +creation_date: 2011-08-08T03:21:30Z + +[Term] +id: GO:2001000 +name: regulation of xylan catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of xylan catabolic process." [GOC:mengo_curators] +synonym: "regulation of xylan breakdown" EXACT [GOC:obol] +synonym: "regulation of xylan catabolism" EXACT [GOC:obol] +synonym: "regulation of xylan degradation" EXACT [GOC:obol] +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +is_a: GO:2000924 ! regulation of cellodextrin metabolic process +is_a: GO:2000966 ! regulation of cell wall polysaccharide catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045493 ! xylan catabolic process +relationship: regulates GO:0045493 ! xylan catabolic process +created_by: tt +creation_date: 2011-08-08T03:23:13Z + +[Term] +id: GO:2001001 +name: negative regulation of xylan catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of xylan breakdown" EXACT [GOC:obol] +synonym: "negative regulation of xylan catabolism" EXACT [GOC:obol] +synonym: "negative regulation of xylan degradation" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000925 ! negative regulation of cellodextrin metabolic process +is_a: GO:2000967 ! negative regulation of cell wall polysaccharide catabolic process +is_a: GO:2001000 ! regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045493 ! xylan catabolic process +relationship: negatively_regulates GO:0045493 ! xylan catabolic process +created_by: tt +creation_date: 2011-08-08T03:23:18Z + +[Term] +id: GO:2001002 +name: positive regulation of xylan catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of xylan catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of xylan breakdown" EXACT [GOC:obol] +synonym: "positive regulation of xylan catabolism" EXACT [GOC:obol] +synonym: "positive regulation of xylan degradation" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:2000926 ! positive regulation of cellodextrin metabolic process +is_a: GO:2000968 ! positive regulation of cell wall polysaccharide catabolic process +is_a: GO:2001000 ! regulation of xylan catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045493 ! xylan catabolic process +relationship: positively_regulates GO:0045493 ! xylan catabolic process +created_by: tt +creation_date: 2011-08-08T03:23:22Z + +[Term] +id: GO:2001003 +name: regulation of pectin catabolic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of pectin catabolic process." [GOC:mengo_curators] +synonym: "regulation of pectin breakdown" EXACT [GOC:obol] +synonym: "regulation of pectin catabolism" EXACT [GOC:obol] +synonym: "regulation of pectin degradation" EXACT [GOC:obol] +is_a: GO:0032881 ! regulation of polysaccharide metabolic process +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0045490 ! pectin catabolic process +relationship: regulates GO:0045490 ! pectin catabolic process +created_by: tt +creation_date: 2011-08-08T03:24:01Z + +[Term] +id: GO:2001004 +name: negative regulation of pectin catabolic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process." [GOC:mengo_curators] +synonym: "negative regulation of pectin breakdown" EXACT [GOC:obol] +synonym: "negative regulation of pectin catabolism" EXACT [GOC:obol] +synonym: "negative regulation of pectin degradation" EXACT [GOC:obol] +is_a: GO:0010605 ! negative regulation of macromolecule metabolic process +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0031330 ! negative regulation of cellular catabolic process +is_a: GO:2001003 ! regulation of pectin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0045490 ! pectin catabolic process +relationship: negatively_regulates GO:0045490 ! pectin catabolic process +created_by: tt +creation_date: 2011-08-08T03:24:06Z + +[Term] +id: GO:2001005 +name: positive regulation of pectin catabolic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of pectin catabolic process." [GOC:mengo_curators] +synonym: "positive regulation of pectin breakdown" EXACT [GOC:obol] +synonym: "positive regulation of pectin catabolism" EXACT [GOC:obol] +synonym: "positive regulation of pectin degradation" EXACT [GOC:obol] +is_a: GO:0010604 ! positive regulation of macromolecule metabolic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031331 ! positive regulation of cellular catabolic process +is_a: GO:2001003 ! regulation of pectin catabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0045490 ! pectin catabolic process +relationship: positively_regulates GO:0045490 ! pectin catabolic process +created_by: tt +creation_date: 2011-08-08T03:24:09Z + +[Term] +id: GO:2001006 +name: regulation of cellulose biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "regulation of cellulose anabolism" EXACT [GOC:obol] +synonym: "regulation of cellulose biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellulose formation" EXACT [GOC:obol] +synonym: "regulation of cellulose synthesis" EXACT [GOC:obol] +is_a: GO:0032951 ! regulation of beta-glucan biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0030244 ! cellulose biosynthetic process +relationship: regulates GO:0030244 ! cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:42:17Z + +[Term] +id: GO:2001007 +name: negative regulation of cellulose biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "negative regulation of cellulose anabolism" EXACT [GOC:obol] +synonym: "negative regulation of cellulose biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellulose formation" EXACT [GOC:obol] +synonym: "negative regulation of cellulose synthesis" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process +is_a: GO:2001006 ! regulation of cellulose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0030244 ! cellulose biosynthetic process +relationship: negatively_regulates GO:0030244 ! cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:42:24Z + +[Term] +id: GO:2001008 +name: positive regulation of cellulose biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "positive regulation of cellulose anabolism" EXACT [GOC:obol] +synonym: "positive regulation of cellulose biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cellulose formation" EXACT [GOC:obol] +synonym: "positive regulation of cellulose synthesis" EXACT [GOC:obol] +is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0031328 ! positive regulation of cellular biosynthetic process +is_a: GO:2001006 ! regulation of cellulose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0030244 ! cellulose biosynthetic process +relationship: positively_regulates GO:0030244 ! cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:42:29Z + +[Term] +id: GO:2001009 +name: regulation of plant-type cell wall cellulose biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "regulation of cell wall cellulose biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellulose biosynthesis during cell wall biosynthesis" RELATED [GOC:obol] +is_a: GO:0010981 ! regulation of cell wall macromolecule metabolic process +is_a: GO:0044087 ! regulation of cellular component biogenesis +is_a: GO:0051128 ! regulation of cellular component organization +is_a: GO:2001006 ! regulation of cellulose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +relationship: regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:47:15Z + +[Term] +id: GO:2001010 +name: negative regulation of plant-type cell wall cellulose biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "negative regulation of cell wall cellulose biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellulose biosynthesis during cell wall biosynthesis" RELATED [GOC:obol] +is_a: GO:0051129 ! negative regulation of cellular component organization +is_a: GO:1903339 ! negative regulation of cell wall organization or biogenesis +is_a: GO:2001007 ! negative regulation of cellulose biosynthetic process +is_a: GO:2001009 ! regulation of plant-type cell wall cellulose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +relationship: negatively_regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:47:22Z + +[Term] +id: GO:2001011 +name: positive regulation of plant-type cell wall cellulose biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process." [GOC:mengo_curators] +synonym: "positive regulation of cell wall cellulose biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cellulose biosynthesis during cell wall biosynthesis" RELATED [GOC:obol] +is_a: GO:0044089 ! positive regulation of cellular component biogenesis +is_a: GO:0051130 ! positive regulation of cellular component organization +is_a: GO:1903340 ! positive regulation of cell wall organization or biogenesis +is_a: GO:2001008 ! positive regulation of cellulose biosynthetic process +is_a: GO:2001009 ! regulation of plant-type cell wall cellulose biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +relationship: positively_regulates GO:0052324 ! plant-type cell wall cellulose biosynthetic process +created_by: tt +creation_date: 2011-08-08T08:47:30Z + +[Term] +id: GO:2001012 +name: mesenchymal cell differentiation involved in renal system development +namespace: biological_process +def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] +synonym: "mesenchymal cell differentiation involved in urinary system development" RELATED [GOC:obol] +synonym: "mesenchymal cell differentiation involved in urinary tract development" RELATED [GOC:obol] +is_a: GO:0048762 ! mesenchymal cell differentiation +intersection_of: GO:0048762 ! mesenchymal cell differentiation +intersection_of: part_of GO:0072001 ! renal system development +relationship: part_of GO:0072001 ! renal system development +created_by: yaf +creation_date: 2011-08-09T04:05:14Z + +[Term] +id: GO:2001013 +name: epithelial cell proliferation involved in renal tubule morphogenesis +namespace: biological_process +def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol] +is_a: GO:0050673 ! epithelial cell proliferation +intersection_of: GO:0050673 ! epithelial cell proliferation +intersection_of: part_of GO:0061333 ! renal tubule morphogenesis +relationship: part_of GO:0061333 ! renal tubule morphogenesis +created_by: yaf +creation_date: 2011-08-12T11:37:29Z + +[Term] +id: GO:2001014 +name: regulation of skeletal muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:0048641 ! regulation of skeletal muscle tissue development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035914 ! skeletal muscle cell differentiation +relationship: regulates GO:0035914 ! skeletal muscle cell differentiation +created_by: yaf +creation_date: 2011-08-11T08:54:37Z + +[Term] +id: GO:2001015 +name: negative regulation of skeletal muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:0048642 ! negative regulation of skeletal muscle tissue development +is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation +relationship: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation +created_by: yaf +creation_date: 2011-08-11T08:54:41Z + +[Term] +id: GO:2001016 +name: positive regulation of skeletal muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development +is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035914 ! skeletal muscle cell differentiation +relationship: positively_regulates GO:0035914 ! skeletal muscle cell differentiation +created_by: yaf +creation_date: 2011-08-11T08:54:44Z + +[Term] +id: GO:2001017 +name: regulation of retrograde axon cargo transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] +synonym: "regulation of retrograde axonal transport" EXACT [GOC:obol] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0060632 ! regulation of microtubule-based movement +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0008090 ! retrograde axonal transport +relationship: regulates GO:0008090 ! retrograde axonal transport +created_by: kmv +creation_date: 2011-08-11T09:44:42Z + +[Term] +id: GO:2001018 +name: negative regulation of retrograde axon cargo transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] +synonym: "negative regulation of retrograde axonal transport" EXACT [GOC:obol] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:0051271 ! negative regulation of cellular component movement +is_a: GO:2001017 ! regulation of retrograde axon cargo transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0008090 ! retrograde axonal transport +relationship: negatively_regulates GO:0008090 ! retrograde axonal transport +created_by: kmv +creation_date: 2011-08-11T09:44:46Z + +[Term] +id: GO:2001019 +name: positive regulation of retrograde axon cargo transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] +synonym: "positive regulation of retrograde axonal transport" EXACT [GOC:obol] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:0051272 ! positive regulation of cellular component movement +is_a: GO:2001017 ! regulation of retrograde axon cargo transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0008090 ! retrograde axonal transport +relationship: positively_regulates GO:0008090 ! retrograde axonal transport +created_by: kmv +creation_date: 2011-08-11T09:44:49Z + +[Term] +id: GO:2001020 +name: regulation of response to DNA damage stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to DNA damage stimulus." [GOC:obol] +synonym: "regulation of cellular DNA damage response" EXACT [GOC:obol] +synonym: "regulation of cellular response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "regulation of DNA damage response" EXACT [GOC:obol] +synonym: "regulation of response to genotoxic stress" EXACT [GOC:obol] +is_a: GO:0080135 ! regulation of cellular response to stress +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006974 ! cellular response to DNA damage stimulus +relationship: regulates GO:0006974 ! cellular response to DNA damage stimulus +created_by: yaf +creation_date: 2011-08-19T10:20:25Z + +[Term] +id: GO:2001021 +name: negative regulation of response to DNA damage stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus." [GOC:obol] +synonym: "negative regulation of cellular DNA damage response" EXACT [GOC:obol] +synonym: "negative regulation of cellular response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "negative regulation of DNA damage response" EXACT [GOC:obol] +synonym: "negative regulation of response to genotoxic stress" EXACT [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006974 ! cellular response to DNA damage stimulus +relationship: negatively_regulates GO:0006974 ! cellular response to DNA damage stimulus +created_by: yaf +creation_date: 2011-08-19T10:20:29Z + +[Term] +id: GO:2001022 +name: positive regulation of response to DNA damage stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus." [GOC:obol] +synonym: "positive regulation of cellular DNA damage response" EXACT [GOC:obol] +synonym: "positive regulation of cellular response to DNA damage stimulus" EXACT [GOC:obol] +synonym: "positive regulation of DNA damage response" EXACT [GOC:obol] +synonym: "positive regulation of response to genotoxic stress" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2001020 ! regulation of response to DNA damage stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006974 ! cellular response to DNA damage stimulus +relationship: positively_regulates GO:0006974 ! cellular response to DNA damage stimulus +created_by: yaf +creation_date: 2011-08-19T10:20:33Z + +[Term] +id: GO:2001023 +name: regulation of response to drug +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to drug." [GOC:obol] +synonym: "regulation of drug resistance" RELATED [GOC:obol] +synonym: "regulation of drug susceptibility/resistance" RELATED [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0042493 ! response to drug +relationship: regulates GO:0042493 ! response to drug +created_by: yaf +creation_date: 2011-08-19T01:47:20Z + +[Term] +id: GO:2001024 +name: negative regulation of response to drug +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to drug." [GOC:obol] +synonym: "negative regulation of drug resistance" RELATED [GOC:obol] +synonym: "negative regulation of drug susceptibility/resistance" RELATED [GOC:obol] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0042493 ! response to drug +relationship: negatively_regulates GO:0042493 ! response to drug +created_by: yaf +creation_date: 2011-08-19T01:47:24Z + +[Term] +id: GO:2001025 +name: positive regulation of response to drug +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to drug." [GOC:obol] +synonym: "positive regulation of drug resistance" RELATED [GOC:obol] +synonym: "positive regulation of drug susceptibility/resistance" RELATED [GOC:obol] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0042493 ! response to drug +relationship: positively_regulates GO:0042493 ! response to drug +created_by: yaf +creation_date: 2011-08-19T01:47:27Z + +[Term] +id: GO:2001026 +name: regulation of endothelial cell chemotaxis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis." [GOC:BHF] +is_a: GO:0010594 ! regulation of endothelial cell migration +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035767 ! endothelial cell chemotaxis +relationship: regulates GO:0035767 ! endothelial cell chemotaxis +created_by: rl +creation_date: 2011-08-22T01:07:26Z + +[Term] +id: GO:2001027 +name: negative regulation of endothelial cell chemotaxis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis." [GOC:BHF] +is_a: GO:0010596 ! negative regulation of endothelial cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:2001026 ! regulation of endothelial cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035767 ! endothelial cell chemotaxis +relationship: negatively_regulates GO:0035767 ! endothelial cell chemotaxis +created_by: rl +creation_date: 2011-08-22T01:07:31Z + +[Term] +id: GO:2001028 +name: positive regulation of endothelial cell chemotaxis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis." [GOC:BHF] +is_a: GO:0010595 ! positive regulation of endothelial cell migration +is_a: GO:0050921 ! positive regulation of chemotaxis +is_a: GO:2001026 ! regulation of endothelial cell chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035767 ! endothelial cell chemotaxis +relationship: positively_regulates GO:0035767 ! endothelial cell chemotaxis +created_by: rl +creation_date: 2011-08-22T01:07:34Z + +[Term] +id: GO:2001029 +name: regulation of cellular glucuronidation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular glucuronidation." [GOC:BHF] +synonym: "regulation of cellular glucuronide biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellular glucuronide biosynthetic process" EXACT [GOC:obol] +synonym: "regulation of cellular glucuronoside biosynthesis" EXACT [GOC:obol] +synonym: "regulation of cellular glucuronoside biosynthetic process" EXACT [GOC:obol] +is_a: GO:0010565 ! regulation of cellular ketone metabolic process +is_a: GO:0010675 ! regulation of cellular carbohydrate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0052695 ! cellular glucuronidation +relationship: regulates GO:0052695 ! cellular glucuronidation +created_by: rl +creation_date: 2011-08-22T01:10:52Z + +[Term] +id: GO:2001030 +name: negative regulation of cellular glucuronidation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation." [GOC:BHF] +synonym: "negative regulation of cellular glucuronide biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellular glucuronide biosynthetic process" EXACT [GOC:obol] +synonym: "negative regulation of cellular glucuronoside biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of cellular glucuronoside biosynthetic process" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process +is_a: GO:2001029 ! regulation of cellular glucuronidation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0052695 ! cellular glucuronidation +relationship: negatively_regulates GO:0052695 ! cellular glucuronidation +created_by: rl +creation_date: 2011-08-22T01:10:56Z + +[Term] +id: GO:2001031 +name: positive regulation of cellular glucuronidation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular glucuronidation." [GOC:BHF] +synonym: "positive regulation of cellular glucuronide biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cellular glucuronide biosynthetic process" EXACT [GOC:obol] +synonym: "positive regulation of cellular glucuronoside biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of cellular glucuronoside biosynthetic process" EXACT [GOC:obol] +is_a: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process +is_a: GO:2001029 ! regulation of cellular glucuronidation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0052695 ! cellular glucuronidation +relationship: positively_regulates GO:0052695 ! cellular glucuronidation +created_by: rl +creation_date: 2011-08-22T01:10:59Z + +[Term] +id: GO:2001032 +name: regulation of double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining." [GOC:obol] +synonym: "regulation of NHEJ" EXACT [GOC:obol] +is_a: GO:2000779 ! regulation of double-strand break repair +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +relationship: regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: yaf +creation_date: 2011-08-24T09:25:39Z + +[Term] +id: GO:2001033 +name: negative regulation of double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining." [GOC:obol] +synonym: "negative regulation of NHEJ" EXACT [GOC:obol] +is_a: GO:2000780 ! negative regulation of double-strand break repair +is_a: GO:2001032 ! regulation of double-strand break repair via nonhomologous end joining +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +relationship: negatively_regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: yaf +creation_date: 2011-08-24T09:25:46Z + +[Term] +id: GO:2001034 +name: positive regulation of double-strand break repair via nonhomologous end joining +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining." [GOC:obol] +synonym: "positive regulation of NHEJ" EXACT [GOC:obol] +is_a: GO:2000781 ! positive regulation of double-strand break repair +is_a: GO:2001032 ! regulation of double-strand break repair via nonhomologous end joining +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +relationship: positively_regulates GO:0006303 ! double-strand break repair via nonhomologous end joining +created_by: yaf +creation_date: 2011-08-24T09:25:51Z + +[Term] +id: GO:2001035 +name: regulation of tongue muscle cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] +is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035981 ! tongue muscle cell differentiation +relationship: regulates GO:0035981 ! tongue muscle cell differentiation +created_by: yaf +creation_date: 2011-08-24T11:10:16Z + +[Term] +id: GO:2001036 +name: negative regulation of tongue muscle cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] +is_a: GO:1902810 ! negative regulation of skeletal muscle fiber differentiation +is_a: GO:2001035 ! regulation of tongue muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035981 ! tongue muscle cell differentiation +relationship: negatively_regulates GO:0035981 ! tongue muscle cell differentiation +created_by: yaf +creation_date: 2011-08-24T11:10:20Z + +[Term] +id: GO:2001037 +name: positive regulation of tongue muscle cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] +is_a: GO:1902811 ! positive regulation of skeletal muscle fiber differentiation +is_a: GO:2001035 ! regulation of tongue muscle cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035981 ! tongue muscle cell differentiation +relationship: positively_regulates GO:0035981 ! tongue muscle cell differentiation +created_by: yaf +creation_date: 2011-08-24T11:10:22Z + +[Term] +id: GO:2001038 +name: regulation of cellular response to drug +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to drug." [GOC:obol] +is_a: GO:0050794 ! regulation of cellular process +is_a: GO:2001023 ! regulation of response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035690 ! cellular response to drug +relationship: regulates GO:0035690 ! cellular response to drug +created_by: yaf +creation_date: 2011-08-27T04:12:19Z + +[Term] +id: GO:2001039 +name: negative regulation of cellular response to drug +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug." [GOC:obol] +is_a: GO:0048523 ! negative regulation of cellular process +is_a: GO:2001024 ! negative regulation of response to drug +is_a: GO:2001038 ! regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035690 ! cellular response to drug +relationship: negatively_regulates GO:0035690 ! cellular response to drug +created_by: yaf +creation_date: 2011-08-27T04:12:23Z + +[Term] +id: GO:2001040 +name: positive regulation of cellular response to drug +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to drug." [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:2001025 ! positive regulation of response to drug +is_a: GO:2001038 ! regulation of cellular response to drug +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035690 ! cellular response to drug +relationship: positively_regulates GO:0035690 ! cellular response to drug +created_by: yaf +creation_date: 2011-08-27T04:12:25Z + +[Term] +id: GO:2001042 +name: negative regulation of septum digestion after cytokinesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis." [GOC:mtg_cell_cycle, GOC:obol] +synonym: "negative regulation of cytokinetic cell separation" EXACT [] +is_a: GO:0010590 ! regulation of septum digestion after cytokinesis +is_a: GO:0051782 ! negative regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0000920 ! septum digestion after cytokinesis +relationship: negatively_regulates GO:0000920 ! septum digestion after cytokinesis +created_by: mcc +creation_date: 2011-08-30T05:16:55Z + +[Term] +id: GO:2001043 +name: positive regulation of septum digestion after cytokinesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis." [GOC:mtg_cell_cycle, GOC:obol] +synonym: "positive regulation of cell separation after cytokinesis" RELATED [] +synonym: "positive regulation of cytokinetic cell separation" RELATED [] +is_a: GO:0010590 ! regulation of septum digestion after cytokinesis +is_a: GO:0051781 ! positive regulation of cell division +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0000920 ! septum digestion after cytokinesis +relationship: positively_regulates GO:0000920 ! septum digestion after cytokinesis +created_by: mcc +creation_date: 2011-08-30T05:16:57Z + +[Term] +id: GO:2001044 +name: regulation of integrin-mediated signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway." [GOC:obol] +synonym: "regulation of integrin-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0007229 ! integrin-mediated signaling pathway +relationship: regulates GO:0007229 ! integrin-mediated signaling pathway +created_by: bf +creation_date: 2011-08-31T03:49:11Z + +[Term] +id: GO:2001045 +name: negative regulation of integrin-mediated signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway." [GOC:obol] +synonym: "negative regulation of integrin-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:2001044 ! regulation of integrin-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0007229 ! integrin-mediated signaling pathway +relationship: negatively_regulates GO:0007229 ! integrin-mediated signaling pathway +created_by: bf +creation_date: 2011-08-31T03:49:16Z + +[Term] +id: GO:2001046 +name: positive regulation of integrin-mediated signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway." [GOC:obol] +synonym: "positive regulation of integrin-mediated signalling pathway" EXACT [GOC:obol] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:2001044 ! regulation of integrin-mediated signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0007229 ! integrin-mediated signaling pathway +relationship: positively_regulates GO:0007229 ! integrin-mediated signaling pathway +created_by: bf +creation_date: 2011-08-31T03:49:19Z + +[Term] +id: GO:2001049 +name: regulation of tendon cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of tendon cell differentiation." [GOC:obol] +synonym: "regulation of muscle attachment cell differentiation" EXACT [GOC:obol] +synonym: "regulation of tenocyte differentiation" RELATED [GOC:obol] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045595 ! regulation of cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035990 ! tendon cell differentiation +relationship: regulates GO:0035990 ! tendon cell differentiation +created_by: yaf +creation_date: 2011-09-01T09:20:32Z + +[Term] +id: GO:2001050 +name: negative regulation of tendon cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation." [GOC:obol] +synonym: "negative regulation of muscle attachment cell differentiation" EXACT [GOC:obol] +synonym: "negative regulation of tenocyte differentiation" RELATED [GOC:obol] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:2001049 ! regulation of tendon cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035990 ! tendon cell differentiation +relationship: negatively_regulates GO:0035990 ! tendon cell differentiation +created_by: yaf +creation_date: 2011-09-01T09:20:38Z + +[Term] +id: GO:2001051 +name: positive regulation of tendon cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of tendon cell differentiation." [GOC:obol] +synonym: "positive regulation of muscle attachment cell differentiation" EXACT [GOC:obol] +synonym: "positive regulation of tenocyte differentiation" RELATED [GOC:obol] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:2001049 ! regulation of tendon cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035990 ! tendon cell differentiation +relationship: positively_regulates GO:0035990 ! tendon cell differentiation +created_by: yaf +creation_date: 2011-09-01T09:20:42Z + +[Term] +id: GO:2001053 +name: regulation of mesenchymal cell apoptotic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "regulation of mesenchymal cell apoptosis" NARROW [] +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097152 ! mesenchymal cell apoptotic process +relationship: regulates GO:0097152 ! mesenchymal cell apoptotic process +created_by: yaf +creation_date: 2011-09-08T02:49:59Z + +[Term] +id: GO:2001054 +name: negative regulation of mesenchymal cell apoptotic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "negative regulation of mesenchymal cell apoptosis" NARROW [] +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process +relationship: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process +created_by: yaf +creation_date: 2011-09-08T02:50:05Z + +[Term] +id: GO:2001055 +name: positive regulation of mesenchymal cell apoptotic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] +synonym: "positive regulation of mesenchymal cell apoptosis" NARROW [] +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process +relationship: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process +created_by: yaf +creation_date: 2011-09-08T02:50:09Z + +[Term] +id: GO:2001056 +name: positive regulation of cysteine-type endopeptidase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity." [GOC:obol] +synonym: "positive regulation of lysosomal cysteine-type endopeptidase" RELATED [GOC:obol] +synonym: "positive regulation of thiol endopeptidase activity" EXACT [GOC:obol] +is_a: GO:0010950 ! positive regulation of endopeptidase activity +is_a: GO:2000116 ! regulation of cysteine-type endopeptidase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0004197 ! cysteine-type endopeptidase activity +relationship: positively_regulates GO:0004197 ! cysteine-type endopeptidase activity +created_by: pr +creation_date: 2011-09-09T08:53:43Z + +[Term] +id: GO:2001057 +name: reactive nitrogen species metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a reactive nitrogen species." [GOC:obol] +synonym: "reactive nitrogen species metabolism" EXACT [GOC:obol] +synonym: "RNS metabolic process" EXACT [GOC:obol] +synonym: "RNS metabolism" EXACT [GOC:obol] +is_a: GO:0006807 ! nitrogen compound metabolic process +created_by: jl +creation_date: 2011-09-09T01:29:13Z + +[Term] +id: GO:2001058 +name: D-tagatose 6-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a D-tagatose 6-phosphate." [GOC:obol] +synonym: "D-tagatose 6-phosphate metabolism" EXACT [GOC:obol] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: jl +creation_date: 2011-09-09T03:21:28Z + +[Term] +id: GO:2001059 +name: D-tagatose 6-phosphate catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate." [GOC:mengo_curators] +synonym: "D-tagatose 6-phosphate catabolism" EXACT [GOC:obol] +xref: UniPathway:UPA00704 +is_a: GO:0046434 ! organophosphate catabolic process +is_a: GO:1901136 ! carbohydrate derivative catabolic process +is_a: GO:2001058 ! D-tagatose 6-phosphate metabolic process +created_by: jl +creation_date: 2011-09-09T03:21:33Z + +[Term] +id: GO:2001060 +name: D-glycero-D-manno-heptose 7-phosphate metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate." [GOC:mengo_curators] +synonym: "D-glycero-D-manno-heptose 7-phosphate metabolism" EXACT [GOC:obol] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:1901135 ! carbohydrate derivative metabolic process +created_by: jl +creation_date: 2011-09-09T03:29:03Z + +[Term] +id: GO:2001061 +name: D-glycero-D-manno-heptose 7-phosphate biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate." [GOC:mengo_curators] +synonym: "D-glycero-D-manno-heptose 7-phosphate biosynthesis" EXACT [GOC:obol] +xref: UniPathway:UPA00041 +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:2001060 ! D-glycero-D-manno-heptose 7-phosphate metabolic process +created_by: jl +creation_date: 2011-09-09T03:29:08Z + +[Term] +id: GO:2001062 +name: xylan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with xylan." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-14T10:10:04Z + +[Term] +id: GO:2001063 +name: glucomannan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glucomannan." [GOC:mengo_curators] +is_a: GO:0008144 ! drug binding +is_a: GO:0010297 ! heteropolysaccharide binding +created_by: jl +creation_date: 2011-09-14T10:29:45Z + +[Term] +id: GO:2001064 +name: cellooligosaccharide binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cellooligosaccharide." [GOC:mengo_curators] +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2011-09-14T10:32:19Z + +[Term] +id: GO:2001065 +name: mannan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with mannan." [GOC:mengo_curators] +synonym: "mannoglycan binding" RELATED [GOC:obol] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-14T10:49:45Z + +[Term] +id: GO:2001066 +name: amylopectin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with amylopectin." [GOC:mengo_curators] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: jl +creation_date: 2011-09-14T11:46:37Z + +[Term] +id: GO:2001067 +name: pullulan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with pullulan." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-14T11:50:06Z + +[Term] +id: GO:2001068 +name: arabinoxylan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with arabinoxylan." [GOC:mengo_curators] +is_a: GO:2001062 ! xylan binding +created_by: jl +creation_date: 2011-09-14T11:58:38Z + +[Term] +id: GO:2001069 +name: glycogen binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with glycogen." [GOC:mengo_curators] +synonym: "animal starch binding" RELATED [GOC:obol] +synonym: "liver starch binding" RELATED [GOC:obol] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-14T12:01:06Z + +[Term] +id: GO:2001070 +name: starch binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with starch." [GOC:mengo_curators] +synonym: "amidon binding" RELATED [GOC:obol] +synonym: "amylum binding" RELATED [GOC:obol] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-14T12:02:50Z + +[Term] +id: GO:2001071 +name: maltoheptaose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with maltoheptaose." [GOC:mengo_curators] +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2011-09-14T12:04:30Z + +[Term] +id: GO:2001072 +name: galactomannan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with galactomannan." [GOC:mengo_curators] +is_a: GO:0010297 ! heteropolysaccharide binding +created_by: jl +creation_date: 2011-09-14T12:12:02Z + +[Term] +id: GO:2001073 +name: cyclodextrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with cyclodextrin." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +is_a: GO:0070492 ! oligosaccharide binding +created_by: jl +creation_date: 2011-09-14T12:24:30Z + +[Term] +id: GO:2001074 +name: regulation of metanephric ureteric bud development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of metanephric ureteric bud development." [GOC:obol] +is_a: GO:0061217 ! regulation of mesonephros development +is_a: GO:0072215 ! regulation of metanephros development +is_a: GO:2000027 ! regulation of animal organ morphogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035502 ! metanephric part of ureteric bud development +relationship: regulates GO:0035502 ! metanephric part of ureteric bud development +created_by: yaf +creation_date: 2011-09-14T01:11:06Z + +[Term] +id: GO:2001075 +name: negative regulation of metanephric ureteric bud development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development." [GOC:obol] +is_a: GO:0061218 ! negative regulation of mesonephros development +is_a: GO:0072217 ! negative regulation of metanephros development +is_a: GO:0110111 ! negative regulation of animal organ morphogenesis +is_a: GO:2001074 ! regulation of metanephric ureteric bud development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035502 ! metanephric part of ureteric bud development +relationship: negatively_regulates GO:0035502 ! metanephric part of ureteric bud development +created_by: yaf +creation_date: 2011-09-14T01:11:12Z + +[Term] +id: GO:2001076 +name: positive regulation of metanephric ureteric bud development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development." [GOC:obol] +is_a: GO:0061213 ! positive regulation of mesonephros development +is_a: GO:0072216 ! positive regulation of metanephros development +is_a: GO:0110110 ! positive regulation of animal organ morphogenesis +is_a: GO:2001074 ! regulation of metanephric ureteric bud development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035502 ! metanephric part of ureteric bud development +relationship: positively_regulates GO:0035502 ! metanephric part of ureteric bud development +created_by: yaf +creation_date: 2011-09-14T01:11:15Z + +[Term] +id: GO:2001077 +name: (1->3),(1->4)-beta-glucan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan." [GOC:mengo_curators] +synonym: "(1,3),(1,4)-beta-glucan binding" EXACT [] +synonym: "1->3,1->4-beta-glucan binding" EXACT [] +synonym: "beta-(1,3),(1,4)-glucan binding" EXACT [] +synonym: "beta-(1->3),(1->4)-glucan binding" EXACT [] +synonym: "beta-1,3-1,4-glucan binding" EXACT [] +synonym: "beta-1->3,1->4-glucan binding" EXACT [] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T09:07:33Z + +[Term] +id: GO:2001078 +name: (1->6)-beta-D-glucan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with (1->6)-beta-D-glucan." [GOC:mengo_curators] +synonym: "(1,6)-beta-D-glucan binding" EXACT [] +synonym: "1,6-beta-D-glucan binding" EXACT [] +synonym: "1->6-beta-D-glucan binding" EXACT [] +synonym: "beta-(1,6)-D-glucan binding" EXACT [] +synonym: "beta-(1->6)-D-glucan binding" EXACT [] +synonym: "beta-1,6-D-glucan binding" EXACT [] +synonym: "beta-1->6-D-glucan binding" EXACT [] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T01:12:50Z + +[Term] +id: GO:2001079 +name: beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc." [GOC:mengo_curators] +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: jl +creation_date: 2011-09-15T01:15:19Z + +[Term] +id: GO:2001080 +name: chitosan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with chitosan." [GOC:mengo_curators] +is_a: GO:0043169 ! cation binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: jl +creation_date: 2011-09-15T01:17:32Z + +[Term] +id: GO:2001081 +name: (1->4)-beta-D-galactan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with (1->4)-beta-D-galactan." [GOC:mengo_curators] +synonym: "(1,4)-beta-D-galactan binding" EXACT [] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T01:21:50Z + +[Term] +id: GO:2001082 +name: inulin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with inulin." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T01:23:59Z + +[Term] +id: GO:2001083 +name: alpha-D-glucan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with alpha-D-glucan." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T01:26:14Z + +[Term] +id: GO:2001084 +name: L-arabinofuranose binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with L-arabinofuranose." [GOC:mengo_curators] +is_a: GO:0048029 ! monosaccharide binding +created_by: jl +creation_date: 2011-09-15T01:33:53Z + +[Term] +id: GO:2001085 +name: arabinogalactan binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with arabinogalactan." [GOC:mengo_curators] +is_a: GO:0030247 ! polysaccharide binding +created_by: jl +creation_date: 2011-09-15T01:35:51Z + +[Term] +id: GO:2001086 +name: laminarabiose transport +namespace: biological_process +def: "The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015766 ! disaccharide transport +created_by: jl +creation_date: 2011-09-21T12:55:01Z + +[Term] +id: GO:2001087 +name: sophorose transport +namespace: biological_process +def: "The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015766 ! disaccharide transport +created_by: jl +creation_date: 2011-09-21T12:58:08Z + +[Term] +id: GO:2001088 +name: trisaccharide transport +namespace: biological_process +def: "The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015772 ! oligosaccharide transport +created_by: jl +creation_date: 2011-09-21T12:59:46Z + +[Term] +id: GO:2001089 +name: maltotriose transport +namespace: biological_process +def: "The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T01:24:26Z + +[Term] +id: GO:2001090 +name: maltotriulose transport +namespace: biological_process +def: "The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T01:44:15Z + +[Term] +id: GO:2001091 +name: nigerotriose transport +namespace: biological_process +def: "The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T01:51:49Z + +[Term] +id: GO:2001092 +name: arabinotriose transport +namespace: biological_process +def: "The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T01:59:36Z + +[Term] +id: GO:2001093 +name: galactotriose transport +namespace: biological_process +def: "The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T02:01:29Z + +[Term] +id: GO:2001094 +name: xylotriose transport +namespace: biological_process +def: "The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T02:03:26Z + +[Term] +id: GO:2001095 +name: mannotriose transport +namespace: biological_process +def: "The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T02:04:52Z + +[Term] +id: GO:2001096 +name: cellotriose transport +namespace: biological_process +def: "The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T02:06:27Z + +[Term] +id: GO:2001097 +name: laminaritriose transport +namespace: biological_process +def: "The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001088 ! trisaccharide transport +created_by: jl +creation_date: 2011-09-21T02:11:36Z + +[Term] +id: GO:2001098 +name: tetrasaccharide transport +namespace: biological_process +def: "The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015772 ! oligosaccharide transport +created_by: jl +creation_date: 2011-09-21T02:12:53Z + +[Term] +id: GO:2001099 +name: maltotetraose transport +namespace: biological_process +def: "The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001098 ! tetrasaccharide transport +created_by: jl +creation_date: 2011-09-21T02:15:03Z + +[Term] +id: GO:2001100 +name: pentasaccharide transport +namespace: biological_process +def: "The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015772 ! oligosaccharide transport +created_by: jl +creation_date: 2011-09-21T02:17:07Z + +[Term] +id: GO:2001101 +name: maltopentaose transport +namespace: biological_process +def: "The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001100 ! pentasaccharide transport +created_by: jl +creation_date: 2011-09-21T02:18:36Z + +[Term] +id: GO:2001102 +name: hexasaccharide transport +namespace: biological_process +def: "The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015772 ! oligosaccharide transport +created_by: jl +creation_date: 2011-09-21T02:20:31Z + +[Term] +id: GO:2001103 +name: maltohexaose transport +namespace: biological_process +def: "The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001102 ! hexasaccharide transport +created_by: jl +creation_date: 2011-09-21T02:21:40Z + +[Term] +id: GO:2001104 +name: heptasaccharide transport +namespace: biological_process +def: "The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:0015772 ! oligosaccharide transport +created_by: jl +creation_date: 2011-09-21T02:29:58Z + +[Term] +id: GO:2001105 +name: maltoheptaose transport +namespace: biological_process +def: "The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mengo_curators] +is_a: GO:2001104 ! heptasaccharide transport +created_by: jl +creation_date: 2011-09-21T02:31:22Z + +[Term] +id: GO:2001106 +name: regulation of Rho guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] +synonym: "regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] +synonym: "regulation of RhoGEF" EXACT [GOC:obol] +is_a: GO:1904475 ! regulation of Ras GTPase binding +is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +relationship: regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +created_by: yaf +creation_date: 2011-09-23T10:13:06Z + +[Term] +id: GO:2001107 +name: negative regulation of Rho guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] +synonym: "negative regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] +synonym: "negative regulation of RhoGEF" EXACT [GOC:obol] +is_a: GO:1904476 ! negative regulation of Ras GTPase binding +is_a: GO:1905098 ! negative regulation of guanyl-nucleotide exchange factor activity +is_a: GO:2001106 ! regulation of Rho guanyl-nucleotide exchange factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +relationship: negatively_regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +created_by: yaf +creation_date: 2011-09-23T10:13:12Z + +[Term] +id: GO:2001108 +name: positive regulation of Rho guanyl-nucleotide exchange factor activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] +synonym: "positive regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] +synonym: "positive regulation of RhoGEF" EXACT [GOC:obol] +is_a: GO:1904477 ! positive regulation of Ras GTPase binding +is_a: GO:1905099 ! positive regulation of guanyl-nucleotide exchange factor activity +is_a: GO:2001106 ! regulation of Rho guanyl-nucleotide exchange factor activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +relationship: positively_regulates GO:0005089 ! Rho guanyl-nucleotide exchange factor activity +created_by: yaf +creation_date: 2011-09-23T10:13:16Z + +[Term] +id: GO:2001109 +name: regulation of lens epithelial cell proliferation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation." [GOC:obol] +is_a: GO:0050678 ! regulation of epithelial cell proliferation +is_a: GO:2000026 ! regulation of multicellular organismal development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097166 ! lens epithelial cell proliferation +relationship: regulates GO:0097166 ! lens epithelial cell proliferation +created_by: yaf +creation_date: 2011-09-30T02:04:53Z + +[Term] +id: GO:2001110 +name: negative regulation of lens epithelial cell proliferation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation." [GOC:obol] +is_a: GO:0050680 ! negative regulation of epithelial cell proliferation +is_a: GO:0051093 ! negative regulation of developmental process +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2001109 ! regulation of lens epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097166 ! lens epithelial cell proliferation +relationship: negatively_regulates GO:0097166 ! lens epithelial cell proliferation +created_by: yaf +creation_date: 2011-09-30T02:04:57Z + +[Term] +id: GO:2001111 +name: positive regulation of lens epithelial cell proliferation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation." [GOC:obol] +is_a: GO:0050679 ! positive regulation of epithelial cell proliferation +is_a: GO:0051094 ! positive regulation of developmental process +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2001109 ! regulation of lens epithelial cell proliferation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097166 ! lens epithelial cell proliferation +relationship: positively_regulates GO:0097166 ! lens epithelial cell proliferation +created_by: yaf +creation_date: 2011-09-30T02:04:59Z + +[Term] +id: GO:2001112 +name: regulation of cellular response to hepatocyte growth factor stimulus +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus." [GOC:obol] +synonym: "regulation of cellular response to HGF stimulus" EXACT [GOC:obol] +is_a: GO:0090287 ! regulation of cellular response to growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +relationship: regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +created_by: dph +creation_date: 2011-10-05T05:43:18Z + +[Term] +id: GO:2001113 +name: negative regulation of cellular response to hepatocyte growth factor stimulus +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus." [GOC:obol] +synonym: "negative regulation of cellular response to HGF stimulus" EXACT [GOC:obol] +is_a: GO:0090288 ! negative regulation of cellular response to growth factor stimulus +is_a: GO:2001112 ! regulation of cellular response to hepatocyte growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +relationship: negatively_regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +created_by: dph +creation_date: 2011-10-05T05:43:23Z + +[Term] +id: GO:2001114 +name: positive regulation of cellular response to hepatocyte growth factor stimulus +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus." [GOC:obol] +synonym: "positive regulation of cellular response to HGF stimulus" EXACT [GOC:obol] +is_a: GO:0048522 ! positive regulation of cellular process +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2001112 ! regulation of cellular response to hepatocyte growth factor stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +relationship: positively_regulates GO:0035729 ! cellular response to hepatocyte growth factor stimulus +created_by: dph +creation_date: 2011-10-05T05:43:26Z + +[Term] +id: GO:2001115 +name: methanopterin-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a methanopterin." [GOC:mengo_curators] +synonym: "methanopterin metabolism" EXACT [GOC:obol] +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +is_a: GO:0042558 ! pteridine-containing compound metabolic process +created_by: jl +creation_date: 2011-10-11T11:54:56Z + +[Term] +id: GO:2001116 +name: methanopterin-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methanopterin." [GOC:mengo_curators] +synonym: "methanopterin biosynthesis" EXACT [GOC:obol] +is_a: GO:0042559 ! pteridine-containing compound biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:2001115 ! methanopterin-containing compound metabolic process +created_by: jl +creation_date: 2011-10-11T11:55:00Z + +[Term] +id: GO:2001117 +name: tetrahydromethanopterin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a tetrahydromethanopterin." [GOC:mengo_curators] +synonym: "tetrahydromethanopterin metabolism" EXACT [GOC:obol] +is_a: GO:2001115 ! methanopterin-containing compound metabolic process +created_by: jl +creation_date: 2011-10-11T12:13:15Z + +[Term] +id: GO:2001118 +name: tetrahydromethanopterin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin." [GOC:mengo_curators] +synonym: "tetrahydromethanopterin biosynthesis" EXACT [GOC:obol] +is_a: GO:2001116 ! methanopterin-containing compound biosynthetic process +is_a: GO:2001117 ! tetrahydromethanopterin metabolic process +created_by: jl +creation_date: 2011-10-11T12:13:19Z + +[Term] +id: GO:2001119 +name: methanofuran metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a methanofuran." [GOC:mengo_curators] +synonym: "methanofuran metabolism" EXACT [GOC:obol] +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: jl +creation_date: 2011-10-11T12:34:08Z + +[Term] +id: GO:2001120 +name: methanofuran biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methanofuran." [GOC:mengo_curators] +synonym: "methanofuran biosynthesis" EXACT [GOC:obol] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:2001119 ! methanofuran metabolic process +created_by: jl +creation_date: 2011-10-11T12:34:12Z + +[Term] +id: GO:2001121 +name: coenzyme gamma-F420-2 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2." [GOC:mengo_curators] +synonym: "coenzyme gamma-F420-2 biosynthesis" EXACT [GOC:obol] +is_a: GO:0009108 ! coenzyme biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0052649 ! coenzyme gamma-F420-2 metabolic process +is_a: GO:0072351 ! tricarboxylic acid biosynthetic process +is_a: GO:0090407 ! organophosphate biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901566 ! organonitrogen compound biosynthetic process +created_by: jl +creation_date: 2011-10-11T02:38:14Z + +[Term] +id: GO:2001122 +name: maltoheptaose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a maltoheptaose." [GOC:mengo_curators] +synonym: "maltoheptaose metabolism" EXACT [GOC:obol] +is_a: GO:0009311 ! oligosaccharide metabolic process +created_by: jl +creation_date: 2011-10-11T02:41:26Z + +[Term] +id: GO:2001123 +name: maltoheptaose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a maltoheptaose." [GOC:mengo_curators] +synonym: "maltoheptaose catabolism" EXACT [GOC:obol] +is_a: GO:0009313 ! oligosaccharide catabolic process +is_a: GO:2001122 ! maltoheptaose metabolic process +created_by: jl +creation_date: 2011-10-11T02:41:29Z + +[Term] +id: GO:2001124 +name: regulation of translational frameshifting +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of translational frameshifting." [GOC:obol] +is_a: GO:0006448 ! regulation of translational elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006452 ! translational frameshifting +relationship: regulates GO:0006452 ! translational frameshifting +created_by: dph +creation_date: 2011-10-12T05:52:22Z + +[Term] +id: GO:2001125 +name: negative regulation of translational frameshifting +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting." [GOC:obol] +is_a: GO:0045900 ! negative regulation of translational elongation +is_a: GO:2001124 ! regulation of translational frameshifting +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006452 ! translational frameshifting +relationship: negatively_regulates GO:0006452 ! translational frameshifting +created_by: dph +creation_date: 2011-10-12T05:52:27Z + +[Term] +id: GO:2001126 +name: positive regulation of translational frameshifting +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of translational frameshifting." [GOC:obol] +is_a: GO:0045901 ! positive regulation of translational elongation +is_a: GO:2001124 ! regulation of translational frameshifting +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006452 ! translational frameshifting +relationship: positively_regulates GO:0006452 ! translational frameshifting +created_by: dph +creation_date: 2011-10-12T05:52:30Z + +[Term] +id: GO:2001127 +name: methane biosynthetic process from formic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a formic acid." [GOC:mengo_curators] +is_a: GO:0015942 ! formate metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T09:54:03Z + +[Term] +id: GO:2001128 +name: methane biosynthetic process from methylamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a methylamine." [GOC:mengo_curators] +is_a: GO:0015948 ! methanogenesis +is_a: GO:0030416 ! methylamine metabolic process +created_by: jl +creation_date: 2011-10-13T10:23:25Z + +[Term] +id: GO:2001129 +name: methane biosynthetic process from dimethylamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine." [GOC:mengo_curators] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T10:26:13Z + +[Term] +id: GO:2001130 +name: methane biosynthetic process from trimethylamine +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine." [GOC:mengo_curators] +is_a: GO:0009308 ! amine metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T10:28:03Z + +[Term] +id: GO:2001131 +name: methane biosynthetic process from dimethyl sulfide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide." [GOC:mengo_curators] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T10:44:31Z + +[Term] +id: GO:2001132 +name: methane biosynthetic process from 3-(methylthio)propionic acid +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid." [GOC:mengo_curators] +is_a: GO:0006631 ! fatty acid metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0009404 ! toxin metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T12:19:33Z + +[Term] +id: GO:2001133 +name: methane biosynthetic process from methanethiol +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a methanethiol." [GOC:mengo_curators] +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0015948 ! methanogenesis +created_by: jl +creation_date: 2011-10-13T12:32:57Z + +[Term] +id: GO:2001134 +name: methane biosynthetic process from carbon monoxide +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide." [GOC:mengo_curators] +is_a: GO:0015948 ! methanogenesis +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0042133 ! neurotransmitter metabolic process +created_by: jl +creation_date: 2011-10-13T12:36:20Z + +[Term] +id: GO:2001135 +name: regulation of endocytic recycling +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of endocytic recycling." [GOC:obol] +synonym: "regulation of retrograde transport of endocytic vesicles" RELATED [GOC:obol] +is_a: GO:0032386 ! regulation of intracellular transport +is_a: GO:0060627 ! regulation of vesicle-mediated transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032456 ! endocytic recycling +relationship: regulates GO:0032456 ! endocytic recycling +created_by: kmv +creation_date: 2011-10-14T03:34:36Z + +[Term] +id: GO:2001136 +name: negative regulation of endocytic recycling +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling." [GOC:obol] +synonym: "negative regulation of retrograde transport of endocytic vesicles" RELATED [GOC:obol] +is_a: GO:0032387 ! negative regulation of intracellular transport +is_a: GO:2001135 ! regulation of endocytic recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0032456 ! endocytic recycling +relationship: negatively_regulates GO:0032456 ! endocytic recycling +created_by: kmv +creation_date: 2011-10-14T03:34:43Z + +[Term] +id: GO:2001137 +name: positive regulation of endocytic recycling +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of endocytic recycling." [GOC:obol] +synonym: "positive regulation of retrograde transport of endocytic vesicles" RELATED [GOC:obol] +is_a: GO:0032388 ! positive regulation of intracellular transport +is_a: GO:2001135 ! regulation of endocytic recycling +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0032456 ! endocytic recycling +relationship: positively_regulates GO:0032456 ! endocytic recycling +created_by: kmv +creation_date: 2011-10-14T03:34:49Z + +[Term] +id: GO:2001138 +name: regulation of phospholipid transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phospholipid transport." [GOC:obol] +is_a: GO:0032368 ! regulation of lipid transport +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0015914 ! phospholipid transport +relationship: regulates GO:0015914 ! phospholipid transport +created_by: kmv +creation_date: 2011-10-14T06:16:06Z + +[Term] +id: GO:2001139 +name: negative regulation of phospholipid transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport." [GOC:obol] +is_a: GO:0032369 ! negative regulation of lipid transport +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:2001138 ! regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0015914 ! phospholipid transport +relationship: negatively_regulates GO:0015914 ! phospholipid transport +created_by: kmv +creation_date: 2011-10-14T06:16:11Z + +[Term] +id: GO:2001140 +name: positive regulation of phospholipid transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phospholipid transport." [GOC:obol] +is_a: GO:0032370 ! positive regulation of lipid transport +is_a: GO:1903793 ! positive regulation of anion transport +is_a: GO:2001138 ! regulation of phospholipid transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0015914 ! phospholipid transport +relationship: positively_regulates GO:0015914 ! phospholipid transport +created_by: kmv +creation_date: 2011-10-14T06:16:14Z + +[Term] +id: GO:2001141 +name: regulation of RNA biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] +synonym: "regulation of RNA anabolism" EXACT [GOC:obol] +synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] +synonym: "regulation of RNA formation" EXACT [GOC:obol] +synonym: "regulation of RNA synthesis" EXACT [GOC:obol] +is_a: GO:0010556 ! regulation of macromolecule biosynthetic process +is_a: GO:0031326 ! regulation of cellular biosynthetic process +is_a: GO:0051252 ! regulation of RNA metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032774 ! RNA biosynthetic process +relationship: regulates GO:0032774 ! RNA biosynthetic process +created_by: dph +creation_date: 2011-10-17T11:36:25Z + +[Term] +id: GO:2001142 +name: nicotinate transport +namespace: biological_process +def: "The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:obol] +is_a: GO:0015718 ! monocarboxylic acid transport +is_a: GO:0015893 ! drug transport +is_a: GO:0051180 ! vitamin transport +is_a: GO:0071705 ! nitrogen compound transport +created_by: tb +creation_date: 2011-10-18T05:09:50Z + +[Term] +id: GO:2001143 +name: N-methylnicotinate transport +namespace: biological_process +def: "The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:obol] +is_a: GO:0015697 ! quaternary ammonium group transport +created_by: tb +creation_date: 2011-10-18T05:16:08Z + +[Term] +id: GO:2001144 +name: regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity." [GOC:obol] +is_a: GO:0010921 ! regulation of phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +relationship: regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +created_by: yaf +creation_date: 2011-10-19T10:41:25Z + +[Term] +id: GO:2001145 +name: negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity." [GOC:obol] +is_a: GO:0010923 ! negative regulation of phosphatase activity +is_a: GO:2001144 ! regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +relationship: negatively_regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +created_by: yaf +creation_date: 2011-10-19T10:41:28Z + +[Term] +id: GO:2001146 +name: positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity." [GOC:obol] +is_a: GO:0010922 ! positive regulation of phosphatase activity +is_a: GO:2001144 ! regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +relationship: positively_regulates GO:0034485 ! phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity +created_by: yaf +creation_date: 2011-10-19T10:41:30Z + +[Term] +id: GO:2001147 +name: camalexin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with camalexin." [GOC:obol] +synonym: "3-(1,3-thiazol-2-yl)-1H-indole binding" EXACT [GOC:obol] +is_a: GO:0097159 ! organic cyclic compound binding +is_a: GO:1901363 ! heterocyclic compound binding +is_a: GO:1901681 ! sulfur compound binding +created_by: tb +creation_date: 2011-10-19T10:54:19Z + +[Term] +id: GO:2001148 +name: regulation of dipeptide transmembrane transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport." [GOC:obol] +synonym: "regulation of dipeptide membrane transport" EXACT [] +is_a: GO:0034762 ! regulation of transmembrane transport +is_a: GO:0090089 ! regulation of dipeptide transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0035442 ! dipeptide transmembrane transport +relationship: regulates GO:0035442 ! dipeptide transmembrane transport +created_by: kmv +creation_date: 2011-10-21T04:34:20Z + +[Term] +id: GO:2001149 +name: negative regulation of dipeptide transmembrane transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport." [GOC:obol] +synonym: "negative regulation of dipeptide membrane transport" EXACT [] +is_a: GO:0034763 ! negative regulation of transmembrane transport +is_a: GO:2000879 ! negative regulation of dipeptide transport +is_a: GO:2001148 ! regulation of dipeptide transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0035442 ! dipeptide transmembrane transport +relationship: negatively_regulates GO:0035442 ! dipeptide transmembrane transport +created_by: kmv +creation_date: 2011-10-21T06:09:59Z + +[Term] +id: GO:2001150 +name: positive regulation of dipeptide transmembrane transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport." [GOC:obol] +synonym: "positive regulation of dipeptide membrane transport" EXACT [] +is_a: GO:0034764 ! positive regulation of transmembrane transport +is_a: GO:2000880 ! positive regulation of dipeptide transport +is_a: GO:2001148 ! regulation of dipeptide transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0035442 ! dipeptide transmembrane transport +relationship: positively_regulates GO:0035442 ! dipeptide transmembrane transport +created_by: kmv +creation_date: 2011-10-21T06:10:03Z + +[Term] +id: GO:2001151 +name: regulation of renal water transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of renal water transport." [GOC:obol] +is_a: GO:0050878 ! regulation of body fluid levels +is_a: GO:0051049 ! regulation of transport +is_a: GO:0098801 ! regulation of renal system process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0003097 ! renal water transport +relationship: regulates GO:0003097 ! renal water transport +created_by: yaf +creation_date: 2011-10-24T11:37:51Z + +[Term] +id: GO:2001152 +name: negative regulation of renal water transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport." [GOC:obol] +is_a: GO:0051051 ! negative regulation of transport +is_a: GO:0051241 ! negative regulation of multicellular organismal process +is_a: GO:2001151 ! regulation of renal water transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0003097 ! renal water transport +relationship: negatively_regulates GO:0003097 ! renal water transport +created_by: yaf +creation_date: 2011-10-24T11:37:57Z + +[Term] +id: GO:2001153 +name: positive regulation of renal water transport +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of renal water transport." [GOC:obol] +is_a: GO:0051050 ! positive regulation of transport +is_a: GO:0051240 ! positive regulation of multicellular organismal process +is_a: GO:2001151 ! regulation of renal water transport +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0003097 ! renal water transport +relationship: positively_regulates GO:0003097 ! renal water transport +created_by: yaf +creation_date: 2011-10-24T11:38:01Z + +[Term] +id: GO:2001154 +name: regulation of glycolytic fermentation to ethanol +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol." [GOC:obol] +synonym: "regulation of ethanol fermentation" EXACT [GOC:obol] +synonym: "regulation of glucose fermentation to ethanol" EXACT [GOC:obol] +is_a: GO:0043465 ! regulation of fermentation +is_a: GO:0043471 ! regulation of cellular carbohydrate catabolic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019655 ! glycolytic fermentation to ethanol +relationship: regulates GO:0019655 ! glycolytic fermentation to ethanol +created_by: mcc +creation_date: 2011-10-27T02:39:00Z + +[Term] +id: GO:2001155 +name: negative regulation of glycolytic fermentation to ethanol +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol." [GOC:obol] +synonym: "negative regulation of ethanol fermentation" EXACT [GOC:obol] +synonym: "negative regulation of glucose fermentation to ethanol" EXACT [GOC:obol] +is_a: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process +is_a: GO:1901003 ! negative regulation of fermentation +is_a: GO:1903579 ! negative regulation of ATP metabolic process +is_a: GO:2001154 ! regulation of glycolytic fermentation to ethanol +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019655 ! glycolytic fermentation to ethanol +relationship: negatively_regulates GO:0019655 ! glycolytic fermentation to ethanol +created_by: mcc +creation_date: 2011-10-27T02:39:05Z + +[Term] +id: GO:2001156 +name: regulation of proline catabolic process to glutamate +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate." [GOC:obol] +synonym: "regulation of proline breakdown to glutamate" EXACT [GOC:obol] +synonym: "regulation of proline degradation to glutamate" EXACT [GOC:obol] +synonym: "regulation of proline oxidation" RELATED [GOC:obol] +is_a: GO:0033241 ! regulation of cellular amine catabolic process +is_a: GO:2000211 ! regulation of glutamate metabolic process +is_a: GO:2000214 ! regulation of proline metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010133 ! proline catabolic process to glutamate +relationship: regulates GO:0010133 ! proline catabolic process to glutamate +created_by: mcc +creation_date: 2011-10-25T08:54:37Z + +[Term] +id: GO:2001157 +name: negative regulation of proline catabolic process to glutamate +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate." [GOC:obol] +synonym: "negative regulation of proline breakdown to glutamate" EXACT [GOC:obol] +synonym: "negative regulation of proline degradation to glutamate" EXACT [GOC:obol] +synonym: "negative regulation of proline oxidation" RELATED [GOC:obol] +is_a: GO:0033242 ! negative regulation of cellular amine catabolic process +is_a: GO:2000212 ! negative regulation of glutamate metabolic process +is_a: GO:2000215 ! negative regulation of proline metabolic process +is_a: GO:2001156 ! regulation of proline catabolic process to glutamate +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010133 ! proline catabolic process to glutamate +relationship: negatively_regulates GO:0010133 ! proline catabolic process to glutamate +created_by: mcc +creation_date: 2011-10-25T08:54:43Z + +[Term] +id: GO:2001158 +name: positive regulation of proline catabolic process to glutamate +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate." [GOC:obol] +synonym: "positive regulation of proline breakdown to glutamate" EXACT [GOC:obol] +synonym: "positive regulation of proline degradation to glutamate" EXACT [GOC:obol] +synonym: "positive regulation of proline oxidation" RELATED [GOC:obol] +is_a: GO:0033243 ! positive regulation of cellular amine catabolic process +is_a: GO:2000213 ! positive regulation of glutamate metabolic process +is_a: GO:2000216 ! positive regulation of proline metabolic process +is_a: GO:2001156 ! regulation of proline catabolic process to glutamate +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010133 ! proline catabolic process to glutamate +relationship: positively_regulates GO:0010133 ! proline catabolic process to glutamate +created_by: mcc +creation_date: 2011-10-25T08:54:50Z + +[Term] +id: GO:2001159 +name: regulation of protein localization by the Cvt pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway." [GOC:obol] +synonym: "regulation of cytoplasm to vacuole targeting" EXACT [GOC:obol] +synonym: "regulation of cytoplasm-to-vacuole targeting" EXACT [GOC:obol] +is_a: GO:1903335 ! regulation of vacuolar transport +is_a: GO:1903533 ! regulation of protein targeting +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0032258 ! cytoplasm to vacuole transport by the Cvt pathway +relationship: regulates GO:0032258 ! cytoplasm to vacuole transport by the Cvt pathway +created_by: jp +creation_date: 2011-10-25T10:22:24Z + +[Term] +id: GO:2001160 +name: regulation of histone H3-K79 methylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K79 methylation." [PMID:12876294] +synonym: "regulation of histone H3 K79 methylation" EXACT [GOC:obol] +synonym: "regulation of histone H3K79me" EXACT [GOC:obol] +synonym: "regulation of histone lysine H3 K79 methylation" EXACT [GOC:obol] +is_a: GO:0031060 ! regulation of histone methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0034729 ! histone H3-K79 methylation +relationship: regulates GO:0034729 ! histone H3-K79 methylation +created_by: se +creation_date: 2011-10-25T10:27:00Z + +[Term] +id: GO:2001161 +name: negative regulation of histone H3-K79 methylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation." [PMID:12876294] +synonym: "negative regulation of histone H3 K79 methylation" EXACT [GOC:obol] +synonym: "negative regulation of histone H3K79me" EXACT [GOC:obol] +synonym: "negative regulation of histone lysine H3 K79 methylation" EXACT [GOC:obol] +is_a: GO:0031061 ! negative regulation of histone methylation +is_a: GO:2001160 ! regulation of histone H3-K79 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0034729 ! histone H3-K79 methylation +relationship: negatively_regulates GO:0034729 ! histone H3-K79 methylation +created_by: se +creation_date: 2011-10-25T10:27:05Z + +[Term] +id: GO:2001162 +name: positive regulation of histone H3-K79 methylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation." [PMID:12876294] +synonym: "positive regulation of histone H3 K79 methylation" EXACT [GOC:obol] +synonym: "positive regulation of histone H3K79me" EXACT [GOC:obol] +synonym: "positive regulation of histone lysine H3 K79 methylation" EXACT [GOC:obol] +is_a: GO:0031062 ! positive regulation of histone methylation +is_a: GO:2001160 ! regulation of histone H3-K79 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0034729 ! histone H3-K79 methylation +relationship: positively_regulates GO:0034729 ! histone H3-K79 methylation +created_by: se +creation_date: 2011-10-25T10:27:10Z + +[Term] +id: GO:2001163 +name: regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues." [PMID:15149594] +is_a: GO:1901407 ! regulation of phosphorylation of RNA polymerase II C-terminal domain +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +relationship: regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +created_by: se +creation_date: 2011-10-25T10:30:59Z + +[Term] +id: GO:2001164 +name: negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues." [PMID:15149594] +is_a: GO:1901408 ! negative regulation of phosphorylation of RNA polymerase II C-terminal domain +is_a: GO:2001163 ! regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +relationship: negatively_regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +created_by: se +creation_date: 2011-10-25T10:31:03Z + +[Term] +id: GO:2001165 +name: positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues." [PMID:15149594] +is_a: GO:1901409 ! positive regulation of phosphorylation of RNA polymerase II C-terminal domain +is_a: GO:2001163 ! regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +relationship: positively_regulates GO:0071619 ! phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +created_by: se +creation_date: 2011-10-25T10:31:07Z + +[Term] +id: GO:2001166 +name: regulation of histone H2B ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H2B ubiquitination." [PMID:12876293] +is_a: GO:0033182 ! regulation of histone ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0033523 ! histone H2B ubiquitination +relationship: regulates GO:0033523 ! histone H2B ubiquitination +created_by: se +creation_date: 2011-10-25T10:49:51Z + +[Term] +id: GO:2001167 +name: negative regulation of histone H2B ubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination." [PMID:12876293] +is_a: GO:0033183 ! negative regulation of histone ubiquitination +is_a: GO:2001166 ! regulation of histone H2B ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0033523 ! histone H2B ubiquitination +relationship: negatively_regulates GO:0033523 ! histone H2B ubiquitination +created_by: se +creation_date: 2011-10-25T10:49:56Z + +[Term] +id: GO:2001168 +name: positive regulation of histone H2B ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination." [PMID:12876293] +is_a: GO:0033184 ! positive regulation of histone ubiquitination +is_a: GO:2001166 ! regulation of histone H2B ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0033523 ! histone H2B ubiquitination +relationship: positively_regulates GO:0033523 ! histone H2B ubiquitination +created_by: se +creation_date: 2011-10-25T10:50:01Z + +[Term] +id: GO:2001169 +name: regulation of ATP biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ATP biosynthetic process." [GOC:obol] +synonym: "regulation of ATP anabolism" EXACT [GOC:obol] +synonym: "regulation of ATP biosynthesis" EXACT [GOC:obol] +synonym: "regulation of ATP formation" EXACT [GOC:obol] +synonym: "regulation of ATP regeneration" RELATED [GOC:obol] +synonym: "regulation of ATP synthesis" EXACT [GOC:obol] +is_a: GO:1900371 ! regulation of purine nucleotide biosynthetic process +is_a: GO:1903578 ! regulation of ATP metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006754 ! ATP biosynthetic process +relationship: regulates GO:0006754 ! ATP biosynthetic process +created_by: kmv +creation_date: 2011-10-26T03:18:03Z + +[Term] +id: GO:2001170 +name: negative regulation of ATP biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process." [GOC:obol] +synonym: "negative regulation of ATP anabolism" EXACT [GOC:obol] +synonym: "negative regulation of ATP biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of ATP formation" EXACT [GOC:obol] +synonym: "negative regulation of ATP regeneration" RELATED [GOC:obol] +synonym: "negative regulation of ATP synthesis" EXACT [GOC:obol] +is_a: GO:1900372 ! negative regulation of purine nucleotide biosynthetic process +is_a: GO:1903579 ! negative regulation of ATP metabolic process +is_a: GO:2001169 ! regulation of ATP biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006754 ! ATP biosynthetic process +relationship: negatively_regulates GO:0006754 ! ATP biosynthetic process +created_by: kmv +creation_date: 2011-10-26T03:18:13Z + +[Term] +id: GO:2001171 +name: positive regulation of ATP biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process." [GOC:obol] +synonym: "positive regulation of ATP anabolism" EXACT [GOC:obol] +synonym: "positive regulation of ATP biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of ATP formation" EXACT [GOC:obol] +synonym: "positive regulation of ATP regeneration" RELATED [GOC:obol] +synonym: "positive regulation of ATP synthesis" EXACT [GOC:obol] +is_a: GO:1900373 ! positive regulation of purine nucleotide biosynthetic process +is_a: GO:1903580 ! positive regulation of ATP metabolic process +is_a: GO:2001169 ! regulation of ATP biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006754 ! ATP biosynthetic process +relationship: positively_regulates GO:0006754 ! ATP biosynthetic process +created_by: kmv +creation_date: 2011-10-26T03:18:26Z + +[Term] +id: GO:2001172 +name: positive regulation of glycolytic fermentation to ethanol +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol." [GOC:obol] +synonym: "positive regulation of ethanol fermentation" EXACT [GOC:obol] +synonym: "positive regulation of glucose fermentation to ethanol" EXACT [GOC:obol] +is_a: GO:0031325 ! positive regulation of cellular metabolic process +is_a: GO:1903580 ! positive regulation of ATP metabolic process +is_a: GO:2001154 ! regulation of glycolytic fermentation to ethanol +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019655 ! glycolytic fermentation to ethanol +relationship: positively_regulates GO:0019655 ! glycolytic fermentation to ethanol +created_by: mcc +creation_date: 2011-10-27T02:39:09Z + +[Term] +id: GO:2001173 +name: regulation of histone H2B conserved C-terminal lysine ubiquitination +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination." [PMID:17576814] +synonym: "regulation of budding yeast H2B K123 ubiquitination" RELATED [GOC:obol] +synonym: "regulation of fission yeast H2B K119 ubiquitination" RELATED [GOC:obol] +synonym: "regulation of mammalian H2B K120 ubiquitination" RELATED [GOC:obol] +is_a: GO:2001166 ! regulation of histone H2B ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +relationship: regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +created_by: se +creation_date: 2011-10-29T06:28:47Z + +[Term] +id: GO:2001174 +name: negative regulation of histone H2B conserved C-terminal lysine ubiquitination +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination." [PMID:17576814] +synonym: "negative regulation of budding yeast H2B K123 ubiquitination" RELATED [GOC:obol] +synonym: "negative regulation of fission yeast H2B K119 ubiquitination" RELATED [GOC:obol] +synonym: "negative regulation of mammalian H2B K120 ubiquitination" RELATED [GOC:obol] +is_a: GO:2001167 ! negative regulation of histone H2B ubiquitination +is_a: GO:2001173 ! regulation of histone H2B conserved C-terminal lysine ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +relationship: negatively_regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +created_by: se +creation_date: 2011-10-29T06:28:53Z + +[Term] +id: GO:2001175 +name: positive regulation of histone H2B conserved C-terminal lysine ubiquitination +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination." [PMID:17576814] +synonym: "positive regulation of budding yeast H2B K123 ubiquitination" RELATED [GOC:obol] +synonym: "positive regulation of fission yeast H2B K119 ubiquitination" RELATED [GOC:obol] +synonym: "positive regulation of mammalian H2B K120 ubiquitination" RELATED [GOC:obol] +is_a: GO:2001168 ! positive regulation of histone H2B ubiquitination +is_a: GO:2001173 ! regulation of histone H2B conserved C-terminal lysine ubiquitination +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +relationship: positively_regulates GO:0071894 ! histone H2B conserved C-terminal lysine ubiquitination +created_by: se +creation_date: 2011-10-29T06:28:59Z + +[Term] +id: GO:2001176 +name: regulation of mediator complex assembly +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of mediator complex assembly." [GOC:obol] +is_a: GO:0043254 ! regulation of protein-containing complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036034 ! mediator complex assembly +relationship: regulates GO:0036034 ! mediator complex assembly +created_by: yaf +creation_date: 2011-11-02T11:22:18Z + +[Term] +id: GO:2001177 +name: negative regulation of mediator complex assembly +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly." [GOC:obol] +is_a: GO:0031333 ! negative regulation of protein-containing complex assembly +is_a: GO:2001176 ! regulation of mediator complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036034 ! mediator complex assembly +relationship: negatively_regulates GO:0036034 ! mediator complex assembly +created_by: yaf +creation_date: 2011-11-02T11:22:23Z + +[Term] +id: GO:2001178 +name: positive regulation of mediator complex assembly +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of mediator complex assembly." [GOC:obol] +is_a: GO:0031334 ! positive regulation of protein-containing complex assembly +is_a: GO:2001176 ! regulation of mediator complex assembly +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036034 ! mediator complex assembly +relationship: positively_regulates GO:0036034 ! mediator complex assembly +created_by: yaf +creation_date: 2011-11-02T11:22:27Z + +[Term] +id: GO:2001179 +name: regulation of interleukin-10 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-10 secretion." [GOC:obol] +synonym: "regulation of IL-10 secretion" EXACT [GOC:obol] +is_a: GO:0032653 ! regulation of interleukin-10 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072608 ! interleukin-10 secretion +relationship: regulates GO:0072608 ! interleukin-10 secretion +created_by: yaf +creation_date: 2011-11-03T10:53:48Z + +[Term] +id: GO:2001180 +name: negative regulation of interleukin-10 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-10 secretion." [GOC:obol] +synonym: "negative regulation of IL-10 secretion" EXACT [GOC:obol] +is_a: GO:0032693 ! negative regulation of interleukin-10 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2001179 ! regulation of interleukin-10 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072608 ! interleukin-10 secretion +relationship: negatively_regulates GO:0072608 ! interleukin-10 secretion +created_by: yaf +creation_date: 2011-11-03T10:53:54Z + +[Term] +id: GO:2001181 +name: positive regulation of interleukin-10 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-10 secretion." [GOC:obol] +synonym: "positive regulation of IL-10 secretion" EXACT [GOC:obol] +is_a: GO:0032733 ! positive regulation of interleukin-10 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2001179 ! regulation of interleukin-10 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072608 ! interleukin-10 secretion +relationship: positively_regulates GO:0072608 ! interleukin-10 secretion +created_by: yaf +creation_date: 2011-11-03T10:53:58Z + +[Term] +id: GO:2001182 +name: regulation of interleukin-12 secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of interleukin-12 secretion." [GOC:obol] +synonym: "regulation of CLMF secretion" RELATED [GOC:obol] +synonym: "regulation of IL-12 secretion" EXACT [GOC:obol] +synonym: "regulation of IL12 secretion" EXACT [GOC:obol] +synonym: "regulation of interleukin-12 complex secretion" EXACT [GOC:obol] +synonym: "regulation of NKSF secretion" RELATED [GOC:obol] +is_a: GO:0032655 ! regulation of interleukin-12 production +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072610 ! interleukin-12 secretion +relationship: regulates GO:0072610 ! interleukin-12 secretion +created_by: yaf +creation_date: 2011-11-03T01:10:29Z + +[Term] +id: GO:2001183 +name: negative regulation of interleukin-12 secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-12 secretion." [GOC:obol] +synonym: "negative regulation of CLMF secretion" RELATED [GOC:obol] +synonym: "negative regulation of IL-12 secretion" EXACT [GOC:obol] +synonym: "negative regulation of IL12 secretion" EXACT [GOC:obol] +synonym: "negative regulation of interleukin-12 complex secretion" EXACT [GOC:obol] +synonym: "negative regulation of NKSF secretion" RELATED [GOC:obol] +is_a: GO:0032695 ! negative regulation of interleukin-12 production +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2001182 ! regulation of interleukin-12 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072610 ! interleukin-12 secretion +relationship: negatively_regulates GO:0072610 ! interleukin-12 secretion +created_by: yaf +creation_date: 2011-11-03T01:10:37Z + +[Term] +id: GO:2001184 +name: positive regulation of interleukin-12 secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion." [GOC:obol] +synonym: "positive regulation of CLMF secretion" RELATED [GOC:obol] +synonym: "positive regulation of IL-12 secretion" EXACT [GOC:obol] +synonym: "positive regulation of IL12 secretion" EXACT [GOC:obol] +synonym: "positive regulation of interleukin-12 complex secretion" EXACT [GOC:obol] +synonym: "positive regulation of NKSF secretion" RELATED [GOC:obol] +is_a: GO:0032735 ! positive regulation of interleukin-12 production +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2001182 ! regulation of interleukin-12 secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072610 ! interleukin-12 secretion +relationship: positively_regulates GO:0072610 ! interleukin-12 secretion +created_by: yaf +creation_date: 2011-11-03T01:10:41Z + +[Term] +id: GO:2001185 +name: regulation of CD8-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046634 ! regulation of alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +relationship: regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +created_by: yaf +creation_date: 2011-11-03T01:16:51Z + +[Term] +id: GO:2001186 +name: negative regulation of CD8-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046636 ! negative regulation of alpha-beta T cell activation +is_a: GO:2001185 ! regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +relationship: negatively_regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +created_by: yaf +creation_date: 2011-11-03T01:16:57Z + +[Term] +id: GO:2001187 +name: positive regulation of CD8-positive, alpha-beta T cell activation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation." [GOC:obol] +is_a: GO:0046635 ! positive regulation of alpha-beta T cell activation +is_a: GO:2001185 ! regulation of CD8-positive, alpha-beta T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +relationship: positively_regulates GO:0036037 ! CD8-positive, alpha-beta T cell activation +created_by: yaf +creation_date: 2011-11-03T01:17:02Z + +[Term] +id: GO:2001188 +name: regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell." [GOC:obol] +synonym: "regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0050776 ! regulation of immune response +is_a: GO:0050863 ! regulation of T cell activation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +relationship: regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +created_by: yaf +creation_date: 2011-11-03T01:31:30Z + +[Term] +id: GO:2001189 +name: negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell." [GOC:obol] +synonym: "negative regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "negative regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "negative regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:0050868 ! negative regulation of T cell activation +is_a: GO:2001188 ! regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +relationship: negatively_regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +created_by: yaf +creation_date: 2011-11-03T01:31:36Z + +[Term] +id: GO:2001190 +name: positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell." [GOC:obol] +synonym: "positive regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "positive regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +synonym: "positive regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" EXACT [GOC:obol] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:0050870 ! positive regulation of T cell activation +is_a: GO:2001188 ! regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +relationship: positively_regulates GO:0002291 ! T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +created_by: yaf +creation_date: 2011-11-03T01:31:40Z + +[Term] +id: GO:2001191 +name: regulation of gamma-delta T cell activation involved in immune response +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol] +synonym: "regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol] +synonym: "regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol] +synonym: "regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol] +synonym: "regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol] +is_a: GO:0002697 ! regulation of immune effector process +is_a: GO:0046643 ! regulation of gamma-delta T cell activation +is_a: GO:0050776 ! regulation of immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +relationship: regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +created_by: yaf +creation_date: 2011-11-03T04:28:38Z + +[Term] +id: GO:2001192 +name: negative regulation of gamma-delta T cell activation involved in immune response +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol] +synonym: "negative regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol] +synonym: "negative regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol] +synonym: "negative regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol] +synonym: "negative regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol] +is_a: GO:0002698 ! negative regulation of immune effector process +is_a: GO:0046644 ! negative regulation of gamma-delta T cell activation +is_a: GO:0050777 ! negative regulation of immune response +is_a: GO:2001191 ! regulation of gamma-delta T cell activation involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +relationship: negatively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +created_by: yaf +creation_date: 2011-11-03T04:28:44Z + +[Term] +id: GO:2001193 +name: positive regulation of gamma-delta T cell activation involved in immune response +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response." [GOC:obol] +synonym: "positive regulation of gamma-delta T cell activation during immune response" RELATED [GOC:obol] +synonym: "positive regulation of gamma-delta T lymphocyte activation during immune response" RELATED [GOC:obol] +synonym: "positive regulation of gamma-delta T-cell activation during immune response" RELATED [GOC:obol] +synonym: "positive regulation of gamma-delta T-lymphocyte activation during immune response" RELATED [GOC:obol] +is_a: GO:0002699 ! positive regulation of immune effector process +is_a: GO:0046645 ! positive regulation of gamma-delta T cell activation +is_a: GO:0050778 ! positive regulation of immune response +is_a: GO:2001191 ! regulation of gamma-delta T cell activation involved in immune response +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +relationship: positively_regulates GO:0002290 ! gamma-delta T cell activation involved in immune response +created_by: yaf +creation_date: 2011-11-03T04:28:48Z + +[Term] +id: GO:2001194 +name: regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine." [GOC:obol] +synonym: "regulation of lysine biosynthesis via aminoadipic acid and saccharopine" EXACT [GOC:obol] +synonym: "regulation of lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT [GOC:obol] +is_a: GO:1902986 ! regulation of lysine biosynthetic process via aminoadipic acid +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +relationship: regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +created_by: mcc +creation_date: 2011-11-03T07:57:11Z + +[Term] +id: GO:2001195 +name: negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine." [GOC:obol] +synonym: "negative regulation of lysine biosynthesis via aminoadipic acid and saccharopine" EXACT [GOC:obol] +synonym: "negative regulation of lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT [GOC:obol] +is_a: GO:1902987 ! negative regulation of lysine biosynthetic process via aminoadipic acid +is_a: GO:2001194 ! regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +relationship: negatively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +created_by: mcc +creation_date: 2011-11-03T07:57:18Z + +[Term] +id: GO:2001196 +name: positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine." [GOC:obol] +synonym: "positive regulation of lysine biosynthesis via aminoadipic acid and saccharopine" EXACT [GOC:obol] +synonym: "positive regulation of lysine biosynthetic process via aminoadipic acid and saccharopine" EXACT [GOC:obol] +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +is_a: GO:2001194 ! regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +relationship: positively_regulates GO:0051975 ! lysine biosynthetic process via alpha-aminoadipate and saccharopine +created_by: mcc +creation_date: 2011-11-03T07:57:24Z + +[Term] +id: GO:2001197 +name: basement membrane assembly involved in embryonic body morphogenesis +namespace: biological_process +def: "Any basement membrane assembly that is involved in embryonic body morphogenesis." [GOC:obol] +is_a: GO:0010927 ! cellular component assembly involved in morphogenesis +is_a: GO:0070831 ! basement membrane assembly +intersection_of: GO:0070831 ! basement membrane assembly +intersection_of: part_of GO:0010172 ! embryonic body morphogenesis +relationship: part_of GO:0010172 ! embryonic body morphogenesis +created_by: kmv +creation_date: 2011-11-03T08:44:33Z + +[Term] +id: GO:2001198 +name: regulation of dendritic cell differentiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] +is_a: GO:1902105 ! regulation of leukocyte differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097028 ! dendritic cell differentiation +relationship: regulates GO:0097028 ! dendritic cell differentiation +created_by: yaf +creation_date: 2011-11-04T02:01:27Z + +[Term] +id: GO:2001199 +name: negative regulation of dendritic cell differentiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] +is_a: GO:1902106 ! negative regulation of leukocyte differentiation +is_a: GO:2001198 ! regulation of dendritic cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097028 ! dendritic cell differentiation +relationship: negatively_regulates GO:0097028 ! dendritic cell differentiation +created_by: yaf +creation_date: 2011-11-04T02:01:33Z + +[Term] +id: GO:2001200 +name: positive regulation of dendritic cell differentiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] +is_a: GO:1902107 ! positive regulation of leukocyte differentiation +is_a: GO:2001198 ! regulation of dendritic cell differentiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097028 ! dendritic cell differentiation +relationship: positively_regulates GO:0097028 ! dendritic cell differentiation +created_by: yaf +creation_date: 2011-11-04T02:01:36Z + +[Term] +id: GO:2001201 +name: regulation of transforming growth factor-beta secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transforming growth factor-beta secretion." [GOC:obol] +synonym: "regulation of TGF-beta secretion" EXACT [GOC:obol] +synonym: "regulation of TGFbeta secretion" EXACT [GOC:obol] +is_a: GO:0050707 ! regulation of cytokine secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038044 ! transforming growth factor-beta secretion +relationship: regulates GO:0038044 ! transforming growth factor-beta secretion +created_by: yaf +creation_date: 2011-11-10T04:29:46Z + +[Term] +id: GO:2001202 +name: negative regulation of transforming growth factor-beta secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor-beta secretion." [GOC:obol] +synonym: "negative regulation of TGF-beta secretion" EXACT [GOC:obol] +synonym: "negative regulation of TGFbeta secretion" EXACT [GOC:obol] +is_a: GO:0050710 ! negative regulation of cytokine secretion +is_a: GO:2001201 ! regulation of transforming growth factor-beta secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038044 ! transforming growth factor-beta secretion +relationship: negatively_regulates GO:0038044 ! transforming growth factor-beta secretion +created_by: yaf +creation_date: 2011-11-10T04:29:52Z + +[Term] +id: GO:2001203 +name: positive regulation of transforming growth factor-beta secretion +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transforming growth factor-beta secretion." [GOC:obol] +synonym: "positive regulation of TGF-beta secretion" EXACT [GOC:obol] +synonym: "positive regulation of TGFbeta secretion" EXACT [GOC:obol] +is_a: GO:0050715 ! positive regulation of cytokine secretion +is_a: GO:2001201 ! regulation of transforming growth factor-beta secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0038044 ! transforming growth factor-beta secretion +relationship: positively_regulates GO:0038044 ! transforming growth factor-beta secretion +created_by: yaf +creation_date: 2011-11-10T04:29:57Z + +[Term] +id: GO:2001204 +name: regulation of osteoclast development +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of osteoclast development." [GOC:obol] +synonym: "regulation of osteoclast cell development" EXACT [GOC:obol] +is_a: GO:0045670 ! regulation of osteoclast differentiation +is_a: GO:0060284 ! regulation of cell development +is_a: GO:1903010 ! regulation of bone development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036035 ! osteoclast development +relationship: regulates GO:0036035 ! osteoclast development +created_by: yaf +creation_date: 2011-11-10T10:58:59Z + +[Term] +id: GO:2001205 +name: negative regulation of osteoclast development +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development." [GOC:obol] +synonym: "negative regulation of osteoclast cell development" EXACT [GOC:obol] +is_a: GO:0010721 ! negative regulation of cell development +is_a: GO:0045671 ! negative regulation of osteoclast differentiation +is_a: GO:1903011 ! negative regulation of bone development +is_a: GO:2001204 ! regulation of osteoclast development +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036035 ! osteoclast development +relationship: negatively_regulates GO:0036035 ! osteoclast development +created_by: yaf +creation_date: 2011-11-10T10:59:06Z + +[Term] +id: GO:2001206 +name: positive regulation of osteoclast development +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of osteoclast development." [GOC:obol] +synonym: "positive regulation of osteoclast cell development" EXACT [GOC:obol] +is_a: GO:0010720 ! positive regulation of cell development +is_a: GO:0045672 ! positive regulation of osteoclast differentiation +is_a: GO:1903012 ! positive regulation of bone development +is_a: GO:2001204 ! regulation of osteoclast development +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0036035 ! osteoclast development +relationship: positively_regulates GO:0036035 ! osteoclast development +created_by: yaf +creation_date: 2011-11-10T10:59:12Z + +[Term] +id: GO:2001207 +name: regulation of transcription elongation from RNA polymerase I promoter +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter." [PMID:20299458] +synonym: "regulation of RNA elongation from Pol I promoter" EXACT [GOC:obol] +is_a: GO:0006356 ! regulation of transcription by RNA polymerase I +is_a: GO:0032784 ! regulation of DNA-templated transcription, elongation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +relationship: regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +created_by: se +creation_date: 2011-11-11T10:46:28Z + +[Term] +id: GO:2001208 +name: negative regulation of transcription elongation by RNA polymerase I +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I." [PMID:20299458] +synonym: "negative regulation of RNA elongation from Pol I promoter" EXACT [GOC:obol] +synonym: "negative regulation of transcription elongation from RNA polymerase I promoter" EXACT [] +is_a: GO:0016479 ! negative regulation of transcription by RNA polymerase I +is_a: GO:0032785 ! negative regulation of DNA-templated transcription, elongation +is_a: GO:2001207 ! regulation of transcription elongation from RNA polymerase I promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +relationship: negatively_regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +created_by: se +creation_date: 2011-11-11T10:46:36Z + +[Term] +id: GO:2001209 +name: positive regulation of transcription elongation from RNA polymerase I promoter +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter." [PMID:20299458] +synonym: "positive regulation of RNA elongation from Pol I promoter" EXACT [GOC:obol] +is_a: GO:0032786 ! positive regulation of DNA-templated transcription, elongation +is_a: GO:0045943 ! positive regulation of transcription by RNA polymerase I +is_a: GO:2001207 ! regulation of transcription elongation from RNA polymerase I promoter +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +relationship: positively_regulates GO:0006362 ! transcription elongation from RNA polymerase I promoter +created_by: se +creation_date: 2011-11-11T10:46:41Z + +[Term] +id: GO:2001210 +name: regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway." [GOC:al] +synonym: "regulation of Ac-MVA pathway" EXACT [GOC:obol] +synonym: "regulation of acetate-mevalonate pathway" EXACT [GOC:obol] +synonym: "regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:obol] +synonym: "regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:obol] +synonym: "regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:obol] +is_a: GO:0019747 ! regulation of isoprenoid metabolic process +is_a: GO:0034248 ! regulation of cellular amide metabolic process +is_a: GO:0042762 ! regulation of sulfur metabolic process +is_a: GO:0051196 ! regulation of coenzyme metabolic process +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +is_a: GO:1900542 ! regulation of purine nucleotide metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +relationship: regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +created_by: bf +creation_date: 2011-11-15T10:53:42Z + +[Term] +id: GO:2001211 +name: negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway." [GOC:al] +synonym: "negative regulation of Ac-MVA pathway" EXACT [GOC:obol] +synonym: "negative regulation of acetate-mevalonate pathway" EXACT [GOC:obol] +synonym: "negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway" EXACT [GOC:obol] +synonym: "negative regulation of isopentenyl diphosphate formation, mevalonate pathway" EXACT [GOC:obol] +synonym: "negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway" EXACT [GOC:obol] +is_a: GO:0034249 ! negative regulation of cellular amide metabolic process +is_a: GO:0045827 ! negative regulation of isoprenoid metabolic process +is_a: GO:0051175 ! negative regulation of sulfur metabolic process +is_a: GO:0051198 ! negative regulation of coenzyme metabolic process +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +is_a: GO:1900543 ! negative regulation of purine nucleotide metabolic process +is_a: GO:2001210 ! regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +relationship: negatively_regulates GO:0019287 ! isopentenyl diphosphate biosynthetic process, mevalonate pathway +created_by: bf +creation_date: 2011-11-15T10:53:45Z + +[Term] +id: GO:2001212 +name: regulation of vasculogenesis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol] +synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol] +is_a: GO:0022603 ! regulation of anatomical structure morphogenesis +is_a: GO:0045595 ! regulation of cell differentiation +is_a: GO:1901342 ! regulation of vasculature development +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001570 ! vasculogenesis +relationship: regulates GO:0001570 ! vasculogenesis +created_by: yaf +creation_date: 2011-11-15T01:22:31Z + +[Term] +id: GO:2001213 +name: negative regulation of vasculogenesis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol] +synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol] +is_a: GO:0045596 ! negative regulation of cell differentiation +is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis +is_a: GO:2001212 ! regulation of vasculogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001570 ! vasculogenesis +relationship: negatively_regulates GO:0001570 ! vasculogenesis +created_by: yaf +creation_date: 2011-11-15T01:22:36Z + +[Term] +id: GO:2001214 +name: positive regulation of vasculogenesis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol] +synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol] +is_a: GO:0045597 ! positive regulation of cell differentiation +is_a: GO:1904018 ! positive regulation of vasculature development +is_a: GO:2001212 ! regulation of vasculogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001570 ! vasculogenesis +relationship: positively_regulates GO:0001570 ! vasculogenesis +created_by: yaf +creation_date: 2011-11-15T01:22:39Z + +[Term] +id: GO:2001215 +name: regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity." [GOC:al] +synonym: "regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" RELATED [GOC:obol] +synonym: "regulation of HMG-CoA reductase activity" RELATED [GOC:obol] +is_a: GO:0051341 ! regulation of oxidoreductase activity +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +relationship: regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +created_by: bf +creation_date: 2011-11-16T11:34:11Z + +[Term] +id: GO:2001216 +name: negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity." [GOC:al] +synonym: "negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" RELATED [GOC:obol] +synonym: "negative regulation of HMG-CoA reductase activity" RELATED [GOC:obol] +is_a: GO:0051354 ! negative regulation of oxidoreductase activity +is_a: GO:2001215 ! regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +relationship: negatively_regulates GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity +created_by: bf +creation_date: 2011-11-16T11:34:17Z + +[Term] +id: GO:2001217 +name: obsolete regulation of S/G2 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of S/G2 transition of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:obol] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "regulation of S/G2 transition of mitotic cell cycle" EXACT [] +is_obsolete: true +consider: GO:0044770 +created_by: dph +creation_date: 2011-11-16T09:14:42Z + +[Term] +id: GO:2001218 +name: obsolete negative regulation of S/G2 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of S/G2 transition of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:obol] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "negative regulation of S/G2 transition of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: dph +creation_date: 2011-11-16T09:14:47Z + +[Term] +id: GO:2001219 +name: obsolete positive regulation of S/G2 transition of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:obol] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "positive regulation of S/G2 transition of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: dph +creation_date: 2011-11-16T09:14:50Z + +[Term] +id: GO:2001220 +name: obsolete negative regulation of G2 phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of G2 phase of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:obol] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "negative regulation of G2 phase of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: yaf +creation_date: 2011-11-17T03:28:44Z + +[Term] +id: GO:2001221 +name: obsolete positive regulation of G2 phase of mitotic cell cycle +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of G2 phase of mitotic cell cycle." [GOC:mtg_cell_cycle, GOC:obol] +comment: This term was made obsolete because it does not refer to a real biological process. +synonym: "positive regulation of G2 phase of mitotic cell cycle" EXACT [] +is_obsolete: true +created_by: yaf +creation_date: 2011-11-17T03:28:48Z + +[Term] +id: GO:2001222 +name: regulation of neuron migration +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol] +synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol] +synonym: "regulation of neuron guidance" RELATED [GOC:obol] +synonym: "regulation of neuronal migration" EXACT [GOC:obol] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050767 ! regulation of neurogenesis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0001764 ! neuron migration +relationship: regulates GO:0001764 ! neuron migration +created_by: kmv +creation_date: 2011-11-17T10:01:38Z + +[Term] +id: GO:2001223 +name: negative regulation of neuron migration +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol] +synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol] +synonym: "negative regulation of neuron guidance" RELATED [GOC:obol] +synonym: "negative regulation of neuronal migration" EXACT [GOC:obol] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050768 ! negative regulation of neurogenesis +is_a: GO:2001222 ! regulation of neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0001764 ! neuron migration +relationship: negatively_regulates GO:0001764 ! neuron migration +created_by: kmv +creation_date: 2011-11-17T10:01:45Z + +[Term] +id: GO:2001224 +name: positive regulation of neuron migration +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol] +synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol] +synonym: "positive regulation of neuron guidance" RELATED [GOC:obol] +synonym: "positive regulation of neuronal migration" EXACT [GOC:obol] +is_a: GO:0030335 ! positive regulation of cell migration +is_a: GO:0050769 ! positive regulation of neurogenesis +is_a: GO:2001222 ! regulation of neuron migration +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0001764 ! neuron migration +relationship: positively_regulates GO:0001764 ! neuron migration +created_by: kmv +creation_date: 2011-11-17T10:01:49Z + +[Term] +id: GO:2001225 +name: regulation of chloride transport +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of chloride transport." [GOC:dph] +is_a: GO:0044070 ! regulation of anion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006821 ! chloride transport +relationship: regulates GO:0006821 ! chloride transport +created_by: dph +creation_date: 2011-11-18T05:45:56Z + +[Term] +id: GO:2001226 +name: negative regulation of chloride transport +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport." [GOC:dph] +is_a: GO:1903792 ! negative regulation of anion transport +is_a: GO:2001225 ! regulation of chloride transport +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006821 ! chloride transport +relationship: negatively_regulates GO:0006821 ! chloride transport +created_by: dph +creation_date: 2011-11-18T05:46:03Z + +[Term] +id: GO:2001227 +name: quercitrin binding +namespace: molecular_function +def: "Interacting selectively and non-covalently with quercitrin." [GOC:obol] +is_a: GO:0008144 ! drug binding +is_a: GO:0043168 ! anion binding +is_a: GO:0097243 ! flavonoid binding +is_a: GO:0097367 ! carbohydrate derivative binding +created_by: tb +creation_date: 2011-11-18T09:58:37Z + +[Term] +id: GO:2001228 +name: regulation of response to gamma radiation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of response to gamma radiation." [GOC:obol] +synonym: "regulation of response to gamma ray" RELATED [GOC:obol] +synonym: "regulation of response to gamma-ray photon" RELATED [GOC:obol] +is_a: GO:0048583 ! regulation of response to stimulus +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0010332 ! response to gamma radiation +relationship: regulates GO:0010332 ! response to gamma radiation +created_by: yaf +creation_date: 2011-11-20T04:51:07Z + +[Term] +id: GO:2001229 +name: negative regulation of response to gamma radiation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation." [GOC:obol] +synonym: "negative regulation of response to gamma ray" RELATED [GOC:obol] +synonym: "negative regulation of response to gamma-ray photon" RELATED [GOC:obol] +is_a: GO:0048585 ! negative regulation of response to stimulus +is_a: GO:2001228 ! regulation of response to gamma radiation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0010332 ! response to gamma radiation +relationship: negatively_regulates GO:0010332 ! response to gamma radiation +created_by: yaf +creation_date: 2011-11-20T04:51:14Z + +[Term] +id: GO:2001230 +name: positive regulation of response to gamma radiation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of response to gamma radiation." [GOC:obol] +synonym: "positive regulation of response to gamma ray" RELATED [GOC:obol] +synonym: "positive regulation of response to gamma-ray photon" RELATED [GOC:obol] +is_a: GO:0048584 ! positive regulation of response to stimulus +is_a: GO:2001228 ! regulation of response to gamma radiation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0010332 ! response to gamma radiation +relationship: positively_regulates GO:0010332 ! response to gamma radiation +created_by: yaf +creation_date: 2011-11-20T04:51:17Z + +[Term] +id: GO:2001231 +name: regulation of protein localization to prospore membrane +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of protein localization to prospore membrane." [GOC:mah] +synonym: "regulation of protein localisation to prospore membrane" EXACT [] +synonym: "regulation of protein targeting to ascospore-type prospore membrane" RELATED [GOC:obol] +synonym: "regulation of protein targeting to forespore membrane" RELATED [GOC:obol] +synonym: "regulation of protein targeting to FSM" RELATED [GOC:obol] +synonym: "regulation of protein targeting to prospore membrane" RELATED [] +synonym: "regulation of protein-prospore membrane targeting" RELATED [GOC:obol] +is_a: GO:1903076 ! regulation of protein localization to plasma membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:1902657 ! protein localization to prospore membrane +relationship: regulates GO:1902657 ! protein localization to prospore membrane +created_by: mah +creation_date: 2011-11-21T04:13:30Z + +[Term] +id: GO:2001232 +name: positive regulation of protein localization to prospore membrane +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane." [GOC:mah] +synonym: "positive regulation of protein localisation to prospore membrane" EXACT [] +synonym: "positive regulation of protein targeting to ascospore-type prospore membrane" RELATED [GOC:obol] +synonym: "positive regulation of protein targeting to forespore membrane" RELATED [GOC:obol] +synonym: "positive regulation of protein targeting to FSM" RELATED [GOC:obol] +synonym: "positive regulation of protein targeting to prospore membrane" RELATED [] +synonym: "positive regulation of protein-prospore membrane targeting" RELATED [GOC:obol] +is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane +is_a: GO:2001231 ! regulation of protein localization to prospore membrane +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:1902657 ! protein localization to prospore membrane +relationship: positively_regulates GO:1902657 ! protein localization to prospore membrane +created_by: mah +creation_date: 2011-11-21T04:13:36Z + +[Term] +id: GO:2001233 +name: regulation of apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:0009966 ! regulation of signal transduction +is_a: GO:0042981 ! regulation of apoptotic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097190 ! apoptotic signaling pathway +relationship: regulates GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:20:49Z + +[Term] +id: GO:2001234 +name: negative regulation of apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:0043066 ! negative regulation of apoptotic process +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097190 ! apoptotic signaling pathway +relationship: negatively_regulates GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:20:54Z + +[Term] +id: GO:2001235 +name: positive regulation of apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:0043065 ! positive regulation of apoptotic process +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097190 ! apoptotic signaling pathway +relationship: positively_regulates GO:0097190 ! apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:20:58Z + +[Term] +id: GO:2001236 +name: regulation of extrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "regulation of extrinsic apoptosis" NARROW [] +synonym: "regulation of extrinsic apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: regulates GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:30:05Z + +[Term] +id: GO:2001237 +name: negative regulation of extrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "negative regulation of extrinsic apoptosis" NARROW [] +synonym: "negative regulation of extrinsic apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +is_a: GO:2001236 ! regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: negatively_regulates GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:30:11Z + +[Term] +id: GO:2001238 +name: positive regulation of extrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "positive regulation of extrinsic apoptosis" NARROW [] +synonym: "positive regulation of extrinsic apoptotic signalling pathway" EXACT [GOC:mah] +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +is_a: GO:2001236 ! regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097191 ! extrinsic apoptotic signaling pathway +relationship: positively_regulates GO:0097191 ! extrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:30:16Z + +[Term] +id: GO:2001239 +name: regulation of extrinsic apoptotic signaling pathway in absence of ligand +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand." [GOC:mtg_apoptosis] +synonym: "regulation of dependence receptor signaling pathway" RELATED [GOC:obol] +synonym: "regulation of extrinsic apoptosis in absence of ligand" NARROW [] +synonym: "regulation of extrinsic apoptotic signalling pathway in absence of ligand" EXACT [GOC:mah] +is_a: GO:2001236 ! regulation of extrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +relationship: regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +created_by: pr +creation_date: 2011-11-24T01:33:18Z + +[Term] +id: GO:2001240 +name: negative regulation of extrinsic apoptotic signaling pathway in absence of ligand +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand." [GOC:mtg_apoptosis] +synonym: "negative regulation of dependence receptor signaling pathway" RELATED [GOC:obol] +synonym: "negative regulation of extrinsic apoptosis in absence of ligand" NARROW [] +synonym: "negative regulation of extrinsic apoptotic signalling pathway in absence of ligand" EXACT [GOC:mah] +is_a: GO:1901099 ! negative regulation of signal transduction in absence of ligand +is_a: GO:2001237 ! negative regulation of extrinsic apoptotic signaling pathway +is_a: GO:2001239 ! regulation of extrinsic apoptotic signaling pathway in absence of ligand +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +relationship: negatively_regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +created_by: pr +creation_date: 2011-11-24T01:33:25Z + +[Term] +id: GO:2001241 +name: positive regulation of extrinsic apoptotic signaling pathway in absence of ligand +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand." [GOC:mtg_apoptosis] +synonym: "positive regulation of dependence receptor signaling pathway" RELATED [GOC:obol] +synonym: "positive regulation of extrinsic apoptosis in absence of ligand" NARROW [] +synonym: "positive regulation of extrinsic apoptotic signalling pathway in absence of ligand" EXACT [GOC:mah] +is_a: GO:2001238 ! positive regulation of extrinsic apoptotic signaling pathway +is_a: GO:2001239 ! regulation of extrinsic apoptotic signaling pathway in absence of ligand +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +relationship: positively_regulates GO:0097192 ! extrinsic apoptotic signaling pathway in absence of ligand +created_by: pr +creation_date: 2011-11-24T01:33:31Z + +[Term] +id: GO:2001242 +name: regulation of intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "regulation of intrinsic apoptosis" NARROW [] +synonym: "regulation of intrinsic apoptotic pathway" EXACT [GOC:obol] +synonym: "regulation of intrinsic apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "regulation of mitochondrial-mediated apoptotic pathway" EXACT [GOC:obol] +is_a: GO:1902531 ! regulation of intracellular signal transduction +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097193 ! intrinsic apoptotic signaling pathway +relationship: regulates GO:0097193 ! intrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:35:56Z + +[Term] +id: GO:2001243 +name: negative regulation of intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "negative regulation of intrinsic apoptosis" NARROW [] +synonym: "negative regulation of intrinsic apoptotic pathway" EXACT [GOC:obol] +synonym: "negative regulation of intrinsic apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of mitochondrial-mediated apoptotic pathway" EXACT [GOC:obol] +is_a: GO:1902532 ! negative regulation of intracellular signal transduction +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097193 ! intrinsic apoptotic signaling pathway +relationship: negatively_regulates GO:0097193 ! intrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:36:03Z + +[Term] +id: GO:2001244 +name: positive regulation of intrinsic apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "positive regulation of intrinsic apoptosis" NARROW [] +synonym: "positive regulation of intrinsic apoptotic pathway" EXACT [GOC:obol] +synonym: "positive regulation of intrinsic apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of mitochondrial-mediated apoptotic pathway" EXACT [GOC:obol] +is_a: GO:1902533 ! positive regulation of intracellular signal transduction +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +is_a: GO:2001242 ! regulation of intrinsic apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097193 ! intrinsic apoptotic signaling pathway +relationship: positively_regulates GO:0097193 ! intrinsic apoptotic signaling pathway +created_by: pr +creation_date: 2011-11-24T01:36:07Z + +[Term] +id: GO:2001245 +name: regulation of phosphatidylcholine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process." [GOC:obol] +synonym: "regulation of phosphatidylcholine anabolism" EXACT [GOC:obol] +synonym: "regulation of phosphatidylcholine biosynthesis" EXACT [GOC:obol] +synonym: "regulation of phosphatidylcholine formation" EXACT [GOC:obol] +synonym: "regulation of phosphatidylcholine synthesis" EXACT [GOC:obol] +is_a: GO:0071071 ! regulation of phospholipid biosynthetic process +is_a: GO:0150172 ! regulation of phosphatidylcholine metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006656 ! phosphatidylcholine biosynthetic process +relationship: regulates GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2011-11-28T09:47:32Z + +[Term] +id: GO:2001246 +name: negative regulation of phosphatidylcholine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process." [GOC:obol] +synonym: "negative regulation of phosphatidylcholine anabolism" EXACT [GOC:obol] +synonym: "negative regulation of phosphatidylcholine biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of phosphatidylcholine formation" EXACT [GOC:obol] +synonym: "negative regulation of phosphatidylcholine synthesis" EXACT [GOC:obol] +is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process +is_a: GO:0071072 ! negative regulation of phospholipid biosynthetic process +is_a: GO:2001245 ! regulation of phosphatidylcholine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0006656 ! phosphatidylcholine biosynthetic process +relationship: negatively_regulates GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2011-11-28T09:47:47Z + +[Term] +id: GO:2001247 +name: positive regulation of phosphatidylcholine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process." [GOC:obol] +synonym: "positive regulation of phosphatidylcholine anabolism" EXACT [GOC:obol] +synonym: "positive regulation of phosphatidylcholine biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of phosphatidylcholine formation" EXACT [GOC:obol] +synonym: "positive regulation of phosphatidylcholine synthesis" EXACT [GOC:obol] +is_a: GO:0071073 ! positive regulation of phospholipid biosynthetic process +is_a: GO:0150173 ! positive regulation of phosphatidylcholine metabolic process +is_a: GO:2001245 ! regulation of phosphatidylcholine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006656 ! phosphatidylcholine biosynthetic process +relationship: positively_regulates GO:0006656 ! phosphatidylcholine biosynthetic process +created_by: tb +creation_date: 2011-11-28T09:47:54Z + +[Term] +id: GO:2001248 +name: regulation of ammonia assimilation cycle +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of ammonia assimilation cycle." [GOC:BHF] +synonym: "regulation of glutamate metabolic process via glutamine and ammonia" EXACT [GOC:obol] +synonym: "regulation of glutamate metabolism via glutamine and ammonia" EXACT [GOC:obol] +is_a: GO:0006808 ! regulation of nitrogen utilization +is_a: GO:2000211 ! regulation of glutamate metabolic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019676 ! ammonia assimilation cycle +relationship: regulates GO:0019676 ! ammonia assimilation cycle +created_by: rl +creation_date: 2011-12-01T10:08:21Z + +[Term] +id: GO:2001249 +name: negative regulation of ammonia assimilation cycle +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle." [GOC:BHF] +synonym: "negative regulation of glutamate metabolic process via glutamine and ammonia" EXACT [GOC:obol] +synonym: "negative regulation of glutamate metabolism via glutamine and ammonia" EXACT [GOC:obol] +is_a: GO:0045847 ! negative regulation of nitrogen utilization +is_a: GO:2000212 ! negative regulation of glutamate metabolic process +is_a: GO:2001248 ! regulation of ammonia assimilation cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019676 ! ammonia assimilation cycle +relationship: negatively_regulates GO:0019676 ! ammonia assimilation cycle +created_by: rl +creation_date: 2011-12-01T10:08:29Z + +[Term] +id: GO:2001250 +name: positive regulation of ammonia assimilation cycle +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle." [GOC:BHF] +synonym: "positive regulation of glutamate metabolic process via glutamine and ammonia" EXACT [GOC:obol] +synonym: "positive regulation of glutamate metabolism via glutamine and ammonia" EXACT [GOC:obol] +is_a: GO:0045848 ! positive regulation of nitrogen utilization +is_a: GO:2000213 ! positive regulation of glutamate metabolic process +is_a: GO:2001248 ! regulation of ammonia assimilation cycle +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019676 ! ammonia assimilation cycle +relationship: positively_regulates GO:0019676 ! ammonia assimilation cycle +created_by: rl +creation_date: 2011-12-01T10:08:34Z + +[Term] +id: GO:2001251 +name: negative regulation of chromosome organization +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol] +synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol] +synonym: "negative regulation of chromosome organization and biogenesis" RELATED [GOC:obol] +synonym: "negative regulation of maintenance of genome integrity" RELATED [GOC:obol] +synonym: "negative regulation of nuclear genome maintenance" RELATED [GOC:obol] +is_a: GO:0010639 ! negative regulation of organelle organization +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0051276 ! chromosome organization +relationship: negatively_regulates GO:0051276 ! chromosome organization +created_by: yaf +creation_date: 2011-12-02T02:01:20Z + +[Term] +id: GO:2001252 +name: positive regulation of chromosome organization +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol] +synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol] +synonym: "positive regulation of chromosome organization and biogenesis" RELATED [GOC:obol] +synonym: "positive regulation of maintenance of genome integrity" RELATED [GOC:obol] +synonym: "positive regulation of nuclear genome maintenance" RELATED [GOC:obol] +is_a: GO:0010638 ! positive regulation of organelle organization +is_a: GO:0033044 ! regulation of chromosome organization +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0051276 ! chromosome organization +relationship: positively_regulates GO:0051276 ! chromosome organization +created_by: yaf +creation_date: 2011-12-02T02:01:26Z + +[Term] +id: GO:2001253 +name: regulation of histone H3-K36 trimethylation +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation." [PMID:17948059] +is_a: GO:0000414 ! regulation of histone H3-K36 methylation +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097198 ! histone H3-K36 trimethylation +relationship: regulates GO:0097198 ! histone H3-K36 trimethylation +created_by: pr +creation_date: 2011-12-06T07:38:09Z + +[Term] +id: GO:2001254 +name: negative regulation of histone H3-K36 trimethylation +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation." [PMID:17948059] +is_a: GO:0000415 ! negative regulation of histone H3-K36 methylation +is_a: GO:2001253 ! regulation of histone H3-K36 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097198 ! histone H3-K36 trimethylation +relationship: negatively_regulates GO:0097198 ! histone H3-K36 trimethylation +created_by: pr +creation_date: 2011-12-06T07:38:17Z + +[Term] +id: GO:2001255 +name: positive regulation of histone H3-K36 trimethylation +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation." [PMID:17948059] +is_a: GO:0000416 ! positive regulation of histone H3-K36 methylation +is_a: GO:2001253 ! regulation of histone H3-K36 trimethylation +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097198 ! histone H3-K36 trimethylation +relationship: positively_regulates GO:0097198 ! histone H3-K36 trimethylation +created_by: pr +creation_date: 2011-12-06T07:38:24Z + +[Term] +id: GO:2001256 +name: regulation of store-operated calcium entry +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of store-operated calcium entry." [GOC:BHF] +synonym: "regulation of calcium ion import" RELATED [GOC:obol] +synonym: "regulation of capacitative calcium entry" EXACT [GOC:obol] +synonym: "regulation of SOCE" EXACT [GOC:obol] +synonym: "regulation of store-operated calcium import" EXACT [GOC:obol] +is_a: GO:0051924 ! regulation of calcium ion transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0002115 ! store-operated calcium entry +relationship: regulates GO:0002115 ! store-operated calcium entry +created_by: vk +creation_date: 2011-12-07T07:08:38Z + +[Term] +id: GO:2001257 +name: regulation of cation channel activity +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cation channel activity." [GOC:BHF] +synonym: "regulation of cation diffusion facilitator activity" EXACT [GOC:obol] +synonym: "regulation of nonselective cation channel activity" EXACT [GOC:obol] +is_a: GO:0032412 ! regulation of ion transmembrane transporter activity +is_a: GO:1904062 ! regulation of cation transmembrane transport +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0005261 ! cation channel activity +relationship: regulates GO:0005261 ! cation channel activity +created_by: vk +creation_date: 2011-12-07T07:14:43Z + +[Term] +id: GO:2001258 +name: negative regulation of cation channel activity +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity." [GOC:BHF] +synonym: "negative regulation of cation diffusion facilitator activity" EXACT [GOC:obol] +synonym: "negative regulation of nonselective cation channel activity" EXACT [GOC:obol] +is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity +is_a: GO:1904063 ! negative regulation of cation transmembrane transport +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0005261 ! cation channel activity +relationship: negatively_regulates GO:0005261 ! cation channel activity +created_by: vk +creation_date: 2011-12-07T07:14:51Z + +[Term] +id: GO:2001259 +name: positive regulation of cation channel activity +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cation channel activity." [GOC:BHF] +synonym: "positive regulation of cation diffusion facilitator activity" EXACT [GOC:obol] +synonym: "positive regulation of nonselective cation channel activity" EXACT [GOC:obol] +is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity +is_a: GO:1904064 ! positive regulation of cation transmembrane transport +is_a: GO:2001257 ! regulation of cation channel activity +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0005261 ! cation channel activity +relationship: positively_regulates GO:0005261 ! cation channel activity +created_by: vk +creation_date: 2011-12-07T07:14:57Z + +[Term] +id: GO:2001260 +name: regulation of semaphorin-plexin signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway." [GOC:BHF] +synonym: "regulation of semaphorin-plexin signalling pathway" EXACT [GOC:obol] +is_a: GO:0009966 ! regulation of signal transduction +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0071526 ! semaphorin-plexin signaling pathway +relationship: regulates GO:0071526 ! semaphorin-plexin signaling pathway +created_by: vk +creation_date: 2011-12-08T02:05:41Z + +[Term] +id: GO:2001261 +name: negative regulation of semaphorin-plexin signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway." [GOC:BHF] +synonym: "negative regulation of semaphorin-plexin signalling pathway" EXACT [GOC:obol] +is_a: GO:0009968 ! negative regulation of signal transduction +is_a: GO:2001260 ! regulation of semaphorin-plexin signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0071526 ! semaphorin-plexin signaling pathway +relationship: negatively_regulates GO:0071526 ! semaphorin-plexin signaling pathway +created_by: vk +creation_date: 2011-12-08T02:05:48Z + +[Term] +id: GO:2001262 +name: positive regulation of semaphorin-plexin signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway." [GOC:BHF] +synonym: "positive regulation of semaphorin-plexin signalling pathway" EXACT [GOC:obol] +is_a: GO:0009967 ! positive regulation of signal transduction +is_a: GO:2001260 ! regulation of semaphorin-plexin signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0071526 ! semaphorin-plexin signaling pathway +relationship: positively_regulates GO:0071526 ! semaphorin-plexin signaling pathway +created_by: vk +creation_date: 2011-12-08T02:05:53Z + +[Term] +id: GO:2001263 +name: regulation of C-C chemokine binding +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of C-C chemokine binding." [GOC:obol] +is_a: GO:0043393 ! regulation of protein binding +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0019957 ! C-C chemokine binding +relationship: regulates GO:0019957 ! C-C chemokine binding +created_by: yaf +creation_date: 2011-12-09T01:13:54Z + +[Term] +id: GO:2001264 +name: negative regulation of C-C chemokine binding +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding." [GOC:obol] +is_a: GO:0032091 ! negative regulation of protein binding +is_a: GO:2001263 ! regulation of C-C chemokine binding +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0019957 ! C-C chemokine binding +relationship: negatively_regulates GO:0019957 ! C-C chemokine binding +created_by: yaf +creation_date: 2011-12-09T01:14:01Z + +[Term] +id: GO:2001265 +name: positive regulation of C-C chemokine binding +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of C-C chemokine binding." [GOC:obol] +is_a: GO:0032092 ! positive regulation of protein binding +is_a: GO:2001263 ! regulation of C-C chemokine binding +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0019957 ! C-C chemokine binding +relationship: positively_regulates GO:0019957 ! C-C chemokine binding +created_by: yaf +creation_date: 2011-12-09T01:14:07Z + +[Term] +id: GO:2001266 +name: Roundabout signaling pathway involved in axon guidance +namespace: biological_process +def: "Any Roundabout signaling pathway that is involved in axon guidance." [GOC:bf, PMID:14527427, PMID:21820427] +synonym: "ROBO signaling pathway involved in axon chemotaxis" RELATED [GOC:obol] +synonym: "ROBO signaling pathway involved in axon growth cone guidance" RELATED [GOC:obol] +synonym: "ROBO signaling pathway involved in axon guidance" EXACT [GOC:obol] +synonym: "ROBO signaling pathway involved in axon pathfinding" EXACT [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in axon chemotaxis" RELATED [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in axon growth cone guidance" RELATED [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in axon guidance" EXACT [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in axon pathfinding" EXACT [GOC:obol] +synonym: "Roundabout signaling pathway involved in axon chemotaxis" RELATED [GOC:obol] +synonym: "Roundabout signaling pathway involved in axon growth cone guidance" RELATED [GOC:obol] +synonym: "Roundabout signaling pathway involved in axon pathfinding" EXACT [GOC:obol] +synonym: "Roundabout signalling pathway involved in axon chemotaxis" RELATED [GOC:obol] +synonym: "Roundabout signalling pathway involved in axon growth cone guidance" RELATED [GOC:obol] +synonym: "Roundabout signalling pathway involved in axon guidance" EXACT [GOC:obol] +synonym: "Roundabout signalling pathway involved in axon pathfinding" EXACT [GOC:obol] +is_a: GO:0035385 ! Roundabout signaling pathway +intersection_of: GO:0035385 ! Roundabout signaling pathway +intersection_of: part_of GO:0007411 ! axon guidance +relationship: part_of GO:0007411 ! axon guidance +created_by: bf +creation_date: 2011-12-12T03:40:20Z + +[Term] +id: GO:2001267 +name: regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "regulation of initiator caspase activity" NARROW [GOC:obol] +is_a: GO:0043281 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:2001233 ! regulation of apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +relationship: regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +created_by: pr +creation_date: 2011-12-13T07:56:13Z + +[Term] +id: GO:2001268 +name: negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "negative regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "negative regulation of initiator caspase activity" NARROW [GOC:obol] +is_a: GO:0043154 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:2001234 ! negative regulation of apoptotic signaling pathway +is_a: GO:2001267 ! regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +relationship: negatively_regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +created_by: pr +creation_date: 2011-12-13T07:56:21Z + +[Term] +id: GO:2001269 +name: positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway." [GOC:mtg_apoptosis] +synonym: "positive regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway" EXACT [GOC:mah] +synonym: "positive regulation of initiator caspase activity" NARROW [GOC:obol] +is_a: GO:0043280 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:2001235 ! positive regulation of apoptotic signaling pathway +is_a: GO:2001267 ! regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +relationship: positively_regulates GO:0097199 ! cysteine-type endopeptidase activity involved in apoptotic signaling pathway +created_by: pr +creation_date: 2011-12-13T07:56:26Z + +[Term] +id: GO:2001270 +name: regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis." [GOC:mtg_apoptosis] +synonym: "regulation of effector caspase activity" NARROW [GOC:obol] +is_a: GO:0043281 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:1900117 ! regulation of execution phase of apoptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +relationship: regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +created_by: pr +creation_date: 2011-12-13T07:59:36Z + +[Term] +id: GO:2001271 +name: negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis." [GOC:mtg_apoptosis] +synonym: "negative regulation of effector caspase activity" NARROW [GOC:obol] +is_a: GO:0043154 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:1900118 ! negative regulation of execution phase of apoptosis +is_a: GO:2001270 ! regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +relationship: negatively_regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +created_by: pr +creation_date: 2011-12-13T07:59:42Z + +[Term] +id: GO:2001272 +name: positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis." [GOC:mtg_apoptosis] +synonym: "positive regulation of effector caspase activity" NARROW [GOC:obol] +is_a: GO:0043280 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process +is_a: GO:1900119 ! positive regulation of execution phase of apoptosis +is_a: GO:2001270 ! regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +relationship: positively_regulates GO:0097200 ! cysteine-type endopeptidase activity involved in execution phase of apoptosis +created_by: pr +creation_date: 2011-12-13T07:59:47Z + +[Term] +id: GO:2001273 +name: obsolete regulation of glucose import in response to insulin stimulus +namespace: biological_process +def: "OBSOLETE. Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus." [GOC:BHF] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "regulation of cellular glucose import in response to insulin stimulus" EXACT [GOC:obol] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15961 xsd:anyURI +is_obsolete: true +created_by: vk +creation_date: 2011-12-13T12:29:31Z + +[Term] +id: GO:2001274 +name: obsolete negative regulation of glucose import in response to insulin stimulus +namespace: biological_process +def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus." [GOC:BHF] +synonym: "negative regulation of cellular glucose import in response to insulin stimulus" EXACT [GOC:obol] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15961 xsd:anyURI +is_obsolete: true +created_by: vk +creation_date: 2011-12-13T12:29:38Z + +[Term] +id: GO:2001275 +name: obsolete positive regulation of glucose import in response to insulin stimulus +namespace: biological_process +def: "OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus." [GOC:BHF] +comment: This term was obsoleted because it represents a GO-CAM model. +synonym: "positive regulation of cellular glucose import in response to insulin stimulus" EXACT [GOC:obol] +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/15961 xsd:anyURI +is_obsolete: true +created_by: vk +creation_date: 2011-12-13T12:29:43Z + +[Term] +id: GO:2001276 +name: regulation of leucine biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of leucine biosynthetic process." [GOC:obol] +synonym: "regulation of leucine anabolism" EXACT [GOC:obol] +synonym: "regulation of leucine biosynthesis" EXACT [GOC:obol] +synonym: "regulation of leucine formation" EXACT [GOC:obol] +synonym: "regulation of leucine synthesis" EXACT [GOC:obol] +is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0009098 ! leucine biosynthetic process +relationship: regulates GO:0009098 ! leucine biosynthetic process +created_by: mcc +creation_date: 2011-12-13T03:13:27Z + +[Term] +id: GO:2001277 +name: negative regulation of leucine biosynthetic process +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process." [GOC:obol] +synonym: "negative regulation of leucine anabolism" EXACT [GOC:obol] +synonym: "negative regulation of leucine biosynthesis" EXACT [GOC:obol] +synonym: "negative regulation of leucine formation" EXACT [GOC:obol] +synonym: "negative regulation of leucine synthesis" EXACT [GOC:obol] +is_a: GO:2000283 ! negative regulation of cellular amino acid biosynthetic process +is_a: GO:2001276 ! regulation of leucine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0009098 ! leucine biosynthetic process +relationship: negatively_regulates GO:0009098 ! leucine biosynthetic process +created_by: mcc +creation_date: 2011-12-13T03:13:36Z + +[Term] +id: GO:2001278 +name: positive regulation of leucine biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process." [GOC:obol] +synonym: "positive regulation of leucine anabolism" EXACT [GOC:obol] +synonym: "positive regulation of leucine biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of leucine formation" EXACT [GOC:obol] +synonym: "positive regulation of leucine synthesis" EXACT [GOC:obol] +is_a: GO:2000284 ! positive regulation of cellular amino acid biosynthetic process +is_a: GO:2001276 ! regulation of leucine biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0009098 ! leucine biosynthetic process +relationship: positively_regulates GO:0009098 ! leucine biosynthetic process +created_by: mcc +creation_date: 2011-12-13T03:13:42Z + +[Term] +id: GO:2001279 +name: regulation of unsaturated fatty acid biosynthetic process +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process." [GO:0006636] +synonym: "regulation of fatty acid desaturation" RELATED [GOC:obol] +synonym: "regulation of polyunsaturated fatty acid biosynthesis" RELATED [GOC:obol] +synonym: "regulation of unsaturated fatty acid anabolism" EXACT [GOC:obol] +synonym: "regulation of unsaturated fatty acid biosynthesis" EXACT [GOC:obol] +synonym: "regulation of unsaturated fatty acid formation" EXACT [GOC:obol] +synonym: "regulation of unsaturated fatty acid synthesis" EXACT [GOC:obol] +is_a: GO:0042304 ! regulation of fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0006636 ! unsaturated fatty acid biosynthetic process +relationship: regulates GO:0006636 ! unsaturated fatty acid biosynthetic process +created_by: dgf +creation_date: 2011-12-14T07:48:26Z + +[Term] +id: GO:2001280 +name: positive regulation of unsaturated fatty acid biosynthetic process +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process." [GO:0006636] +synonym: "positive regulation of fatty acid desaturation" RELATED [GOC:obol] +synonym: "positive regulation of polyunsaturated fatty acid biosynthesis" RELATED [GOC:obol] +synonym: "positive regulation of unsaturated fatty acid anabolism" EXACT [GOC:obol] +synonym: "positive regulation of unsaturated fatty acid biosynthesis" EXACT [GOC:obol] +synonym: "positive regulation of unsaturated fatty acid formation" EXACT [GOC:obol] +synonym: "positive regulation of unsaturated fatty acid synthesis" EXACT [GOC:obol] +is_a: GO:0045723 ! positive regulation of fatty acid biosynthetic process +is_a: GO:2001279 ! regulation of unsaturated fatty acid biosynthetic process +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0006636 ! unsaturated fatty acid biosynthetic process +relationship: positively_regulates GO:0006636 ! unsaturated fatty acid biosynthetic process +created_by: dgf +creation_date: 2011-12-14T07:48:33Z + +[Term] +id: GO:2001281 +name: regulation of muscle cell chemotaxis toward tendon cell +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell." [GOC:sart] +synonym: "regulation of muscle cell attraction" RELATED [GOC:obol] +synonym: "regulation of muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +is_a: GO:0030334 ! regulation of cell migration +is_a: GO:0050920 ! regulation of chemotaxis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0036061 ! muscle cell chemotaxis toward tendon cell +relationship: regulates GO:0036061 ! muscle cell chemotaxis toward tendon cell +created_by: bf +creation_date: 2011-12-15T10:39:36Z + +[Term] +id: GO:2001282 +name: negative regulation of muscle cell chemotaxis toward tendon cell +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells." [GOC:sart, PMID:19793885, PMID:20404543] +synonym: "arrest of muscle cell chemotaxis" NARROW [GOC:bf, GOC:sart, PMID:19793885] +synonym: "negative regulation of muscle cell attraction" RELATED [GOC:obol] +synonym: "negative regulation of muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +is_a: GO:0030336 ! negative regulation of cell migration +is_a: GO:0050922 ! negative regulation of chemotaxis +is_a: GO:2001281 ! regulation of muscle cell chemotaxis toward tendon cell +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0036061 ! muscle cell chemotaxis toward tendon cell +relationship: negatively_regulates GO:0036061 ! muscle cell chemotaxis toward tendon cell +created_by: bf +creation_date: 2011-12-15T10:39:42Z + +[Term] +id: GO:2001283 +name: Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell +namespace: biological_process +def: "Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus." [GOC:bf, GOC:obol, GOC:sart, PMID:19793885] +synonym: "ROBO signaling pathway involved in muscle cell attraction" RELATED [GOC:obol] +synonym: "ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell" EXACT [GOC:obol] +synonym: "ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in muscle cell attraction" RELATED [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in muscle cell chemotaxis toward tendon cell" EXACT [GOC:obol] +synonym: "ROBO/SLIT signaling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +synonym: "Roundabout signaling pathway involved in muscle cell attraction" RELATED [GOC:obol] +synonym: "Roundabout signaling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +synonym: "Roundabout signalling pathway involved in muscle cell attraction" RELATED [GOC:obol] +synonym: "Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell" EXACT [GOC:obol] +synonym: "Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell" EXACT [GOC:obol] +is_a: GO:0035385 ! Roundabout signaling pathway +intersection_of: GO:0035385 ! Roundabout signaling pathway +intersection_of: part_of GO:0036061 ! muscle cell chemotaxis toward tendon cell +relationship: part_of GO:0036061 ! muscle cell chemotaxis toward tendon cell +created_by: bf +creation_date: 2011-12-15T10:42:03Z + +[Term] +id: GO:2001284 +name: regulation of BMP secretion +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of BMP secretion." [GOC:sart] +synonym: "regulation of BMP protein secretion" EXACT [GOC:obol] +synonym: "regulation of bone morphogenetic protein secretion" EXACT [GOC:obol] +is_a: GO:0010646 ! regulation of cell communication +is_a: GO:0023051 ! regulation of signaling +is_a: GO:0050708 ! regulation of protein secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0038055 ! BMP secretion +relationship: regulates GO:0038055 ! BMP secretion +created_by: bf +creation_date: 2011-12-15T02:15:28Z + +[Term] +id: GO:2001285 +name: negative regulation of BMP secretion +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion." [GOC:sart] +synonym: "negative regulation of BMP protein secretion" EXACT [GOC:obol] +synonym: "negative regulation of bone morphogenetic protein secretion" EXACT [GOC:obol] +is_a: GO:0010648 ! negative regulation of cell communication +is_a: GO:0023057 ! negative regulation of signaling +is_a: GO:0050709 ! negative regulation of protein secretion +is_a: GO:2001284 ! regulation of BMP secretion +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0038055 ! BMP secretion +relationship: negatively_regulates GO:0038055 ! BMP secretion +created_by: bf +creation_date: 2011-12-15T02:15:36Z + +[Term] +id: GO:2001286 +name: regulation of caveolin-mediated endocytosis +namespace: biological_process +def: "Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis." [GOC:obol] +synonym: "regulation of caveolae-dependent endocytosis" EXACT [GOC:obol] +synonym: "regulation of caveolae-mediated endocytosis" EXACT [GOC:obol] +synonym: "regulation of caveolin-dependent endocytosis" EXACT [GOC:obol] +is_a: GO:0030100 ! regulation of endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: regulates GO:0072584 ! caveolin-mediated endocytosis +relationship: regulates GO:0072584 ! caveolin-mediated endocytosis +created_by: yaf +creation_date: 2011-12-15T04:13:19Z + +[Term] +id: GO:2001287 +name: negative regulation of caveolin-mediated endocytosis +namespace: biological_process +def: "Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis." [GOC:obol] +synonym: "negative regulation of caveolae-dependent endocytosis" EXACT [GOC:obol] +synonym: "negative regulation of caveolae-mediated endocytosis" EXACT [GOC:obol] +synonym: "negative regulation of caveolin-dependent endocytosis" EXACT [GOC:obol] +is_a: GO:0045806 ! negative regulation of endocytosis +is_a: GO:2001286 ! regulation of caveolin-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: negatively_regulates GO:0072584 ! caveolin-mediated endocytosis +relationship: negatively_regulates GO:0072584 ! caveolin-mediated endocytosis +created_by: yaf +creation_date: 2011-12-15T04:13:27Z + +[Term] +id: GO:2001288 +name: positive regulation of caveolin-mediated endocytosis +namespace: biological_process +def: "Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis." [GOC:obol] +synonym: "positive regulation of caveolae-dependent endocytosis" EXACT [GOC:obol] +synonym: "positive regulation of caveolae-mediated endocytosis" EXACT [GOC:obol] +synonym: "positive regulation of caveolin-dependent endocytosis" EXACT [GOC:obol] +is_a: GO:0045807 ! positive regulation of endocytosis +is_a: GO:2001286 ! regulation of caveolin-mediated endocytosis +intersection_of: GO:0008150 ! biological_process +intersection_of: positively_regulates GO:0072584 ! caveolin-mediated endocytosis +relationship: positively_regulates GO:0072584 ! caveolin-mediated endocytosis +created_by: yaf +creation_date: 2011-12-15T04:13:32Z + +[Term] +id: GO:2001289 +name: lipid X metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate." [GOC:obol] +synonym: "2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolic process" RELATED [GOC:obol] +synonym: "2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolism" RELATED [GOC:obol] +synonym: "2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolic process" RELATED [GOC:obol] +synonym: "2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolism" RELATED [GOC:obol] +synonym: "2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolic process" EXACT [GOC:obol] +synonym: "2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolism" EXACT [GOC:obol] +synonym: "Lipid X metabolic process" EXACT [GOC:obol] +synonym: "Lipid X metabolism" EXACT [GOC:obol] +synonym: "lipid X metabolism" EXACT [GOC:obol] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0006796 ! phosphate-containing compound metabolic process +is_a: GO:0019637 ! organophosphate metabolic process +created_by: tb +creation_date: 2012-01-13T11:28:58Z + +[Term] +id: GO:2001290 +name: hydroperoxide metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a hydroperoxide." [GOC:rs, PMID:15917183, PMID:18084891] +synonym: "hydroperoxide metabolism" EXACT [GOC:obol] +is_a: GO:0044237 ! cellular metabolic process +created_by: pr +creation_date: 2012-02-09T03:35:37Z + +[Term] +id: GO:2001291 +name: codeine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties." [GOC:yaf] +synonym: "codeine metabolism" EXACT [GOC:obol] +is_a: GO:0006805 ! xenobiotic metabolic process +is_a: GO:0017144 ! drug metabolic process +is_a: GO:0033076 ! isoquinoline alkaloid metabolic process +is_a: GO:1901376 ! organic heteropentacyclic compound metabolic process +created_by: pr +creation_date: 2012-02-14T01:10:03Z + +[Term] +id: GO:2001292 +name: codeine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties." [GOC:yaf, UniPathway:UPA00318] +synonym: "codeine breakdown" EXACT [GOC:obol] +synonym: "codeine catabolism" EXACT [GOC:obol] +synonym: "codeine degradation" EXACT [GOC:obol] +is_a: GO:0042178 ! xenobiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0071274 ! isoquinoline alkaloid catabolic process +is_a: GO:1901377 ! organic heteropentacyclic compound catabolic process +is_a: GO:2001291 ! codeine metabolic process +created_by: pr +creation_date: 2012-02-14T01:10:09Z + +[Term] +id: GO:2001293 +name: malonyl-CoA metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A." [GOC:yaf, PMID:11902724, PMID:15726818, PMID:18981598] +synonym: "malonyl-CoA metabolism" EXACT [GOC:obol] +is_a: GO:0006637 ! acyl-CoA metabolic process +created_by: pr +creation_date: 2012-02-14T02:23:11Z + +[Term] +id: GO:2001294 +name: malonyl-CoA catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A." [GOC:yaf] +synonym: "malonyl-CoA breakdown" EXACT [GOC:obol] +synonym: "malonyl-CoA catabolism" EXACT [GOC:obol] +synonym: "malonyl-CoA degradation" EXACT [GOC:obol] +is_a: GO:0009154 ! purine ribonucleotide catabolic process +is_a: GO:0034031 ! ribonucleoside bisphosphate catabolic process +is_a: GO:0034034 ! purine nucleoside bisphosphate catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:2001293 ! malonyl-CoA metabolic process +created_by: pr +creation_date: 2012-02-14T02:23:17Z + +[Term] +id: GO:2001295 +name: malonyl-CoA biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A." [GOC:yaf, UniPathway:UPA00655] +synonym: "malonyl-CoA anabolism" EXACT [GOC:obol] +synonym: "malonyl-CoA biosynthesis" EXACT [GOC:obol] +synonym: "malonyl-CoA formation" EXACT [GOC:obol] +synonym: "malonyl-CoA synthesis" EXACT [GOC:obol] +is_a: GO:0071616 ! acyl-CoA biosynthetic process +is_a: GO:2001293 ! malonyl-CoA metabolic process +created_by: pr +creation_date: 2012-02-14T02:23:21Z + +[Term] +id: GO:2001296 +name: N(omega)-methyl-L-arginine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N(omega)-methyl-L-arginine." [GOC:rs, PMID:10510241] +synonym: "N(omega)-methyl-L-arginine metabolism" EXACT [GOC:obol] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: pr +creation_date: 2012-02-14T03:38:16Z + +[Term] +id: GO:2001297 +name: N(omega)-methyl-L-arginine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine." [GOC:rs, PMID:10510241] +synonym: "N(omega)-methyl-L-arginine breakdown" EXACT [GOC:obol] +synonym: "N(omega)-methyl-L-arginine catabolism" EXACT [GOC:obol] +synonym: "N(omega)-methyl-L-arginine degradation" EXACT [GOC:obol] +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +is_a: GO:2001296 ! N(omega)-methyl-L-arginine metabolic process +created_by: pr +creation_date: 2012-02-14T03:38:21Z + +[Term] +id: GO:2001298 +name: N(omega),N(omega)-dimethyl-L-arginine metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group." [GOC:rs, PMID:10510241] +synonym: "N(omega),N(omega)-dimethyl-L-arginine metabolism" EXACT [GOC:obol] +is_a: GO:0006575 ! cellular modified amino acid metabolic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +created_by: pr +creation_date: 2012-02-14T03:39:59Z + +[Term] +id: GO:2001299 +name: N(omega),N(omega)-dimethyl-L-arginine catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group." [GOC:rs, PMID:10510241] +synonym: "N(omega),N(omega)-dimethyl-L-arginine breakdown" EXACT [GOC:obol] +synonym: "N(omega),N(omega)-dimethyl-L-arginine catabolism" EXACT [GOC:obol] +synonym: "N(omega),N(omega)-dimethyl-L-arginine degradation" EXACT [GOC:obol] +is_a: GO:0042219 ! cellular modified amino acid catabolic process +is_a: GO:1901606 ! alpha-amino acid catabolic process +is_a: GO:2001298 ! N(omega),N(omega)-dimethyl-L-arginine metabolic process +created_by: pr +creation_date: 2012-02-14T03:40:03Z + +[Term] +id: GO:2001300 +name: lipoxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid." [GOC:mw] +synonym: "lipoxin metabolism" EXACT [GOC:obol] +is_a: GO:0006690 ! icosanoid metabolic process +is_a: GO:0033559 ! unsaturated fatty acid metabolic process +created_by: bf +creation_date: 2012-03-07T11:11:08Z + +[Term] +id: GO:2001301 +name: lipoxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid." [GOC:mw] +synonym: "lipoxin anabolism" EXACT [GOC:obol] +synonym: "lipoxin biosynthesis" EXACT [GOC:obol] +synonym: "lipoxin formation" EXACT [GOC:obol] +synonym: "lipoxin synthesis" EXACT [GOC:obol] +is_a: GO:0006636 ! unsaturated fatty acid biosynthetic process +is_a: GO:0046456 ! icosanoid biosynthetic process +is_a: GO:2001300 ! lipoxin metabolic process +created_by: bf +creation_date: 2012-03-07T11:11:13Z + +[Term] +id: GO:2001302 +name: lipoxin A4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds." [GOC:mw] +synonym: "lipoxin A4 metabolism" EXACT [GOC:obol] +synonym: "LXA4 metabolic process" EXACT [GOC:obol] +synonym: "LXA4 metabolism" EXACT [GOC:obol] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +is_a: GO:2001300 ! lipoxin metabolic process +created_by: bf +creation_date: 2012-03-07T11:13:12Z + +[Term] +id: GO:2001303 +name: lipoxin A4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds." [GOC:mw] +synonym: "lipoxin A4 anabolism" EXACT [GOC:obol] +synonym: "lipoxin A4 biosynthesis" EXACT [GOC:obol] +synonym: "lipoxin A4 formation" EXACT [GOC:obol] +synonym: "lipoxin A4 synthesis" EXACT [GOC:obol] +synonym: "LXA4 anabolism" EXACT [GOC:obol] +synonym: "LXA4 biosynthesis" EXACT [GOC:obol] +synonym: "LXA4 biosynthetic process" EXACT [GOC:obol] +synonym: "LXA4 formation" EXACT [GOC:obol] +synonym: "LXA4 synthesis" EXACT [GOC:obol] +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:2001301 ! lipoxin biosynthetic process +is_a: GO:2001302 ! lipoxin A4 metabolic process +created_by: bf +creation_date: 2012-03-07T11:13:18Z + +[Term] +id: GO:2001304 +name: lipoxin B4 metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds." [GOC:mw] +synonym: "lipoxin B4 metabolism" EXACT [GOC:obol] +synonym: "LXB4 metabolic process" EXACT [GOC:obol] +synonym: "LXB4 metabolism" EXACT [GOC:obol] +is_a: GO:0001676 ! long-chain fatty acid metabolic process +is_a: GO:1901615 ! organic hydroxy compound metabolic process +is_a: GO:2001300 ! lipoxin metabolic process +created_by: bf +creation_date: 2012-03-07T11:14:58Z + +[Term] +id: GO:2001305 +name: xanthone-containing compound metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a xanthone-containing compound." [GOC:di] +synonym: "xanthone metabolism" NARROW [CHEBI:37647] +synonym: "xanthone-containing compound metabolism" EXACT [GOC:obol] +synonym: "xanthones metabolic process" EXACT [GOC:obol] +synonym: "xanthones metabolism" EXACT [GOC:obol] +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: bf +creation_date: 2012-03-14T10:35:38Z + +[Term] +id: GO:2001306 +name: lipoxin B4 biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds." [GOC:mw] +synonym: "lipoxin B4 anabolism" EXACT [GOC:obol] +synonym: "lipoxin B4 biosynthesis" EXACT [GOC:obol] +synonym: "lipoxin B4 formation" EXACT [GOC:obol] +synonym: "lipoxin B4 synthesis" EXACT [GOC:obol] +synonym: "LXB4 anabolism" EXACT [GOC:obol] +synonym: "LXB4 biosynthesis" EXACT [GOC:obol] +synonym: "LXB4 biosynthetic process" EXACT [GOC:obol] +synonym: "LXB4 formation" EXACT [GOC:obol] +synonym: "LXB4 synthesis" EXACT [GOC:obol] +is_a: GO:0042759 ! long-chain fatty acid biosynthetic process +is_a: GO:1901617 ! organic hydroxy compound biosynthetic process +is_a: GO:2001301 ! lipoxin biosynthetic process +is_a: GO:2001304 ! lipoxin B4 metabolic process +created_by: bf +creation_date: 2012-03-07T11:15:04Z + +[Term] +id: GO:2001307 +name: xanthone-containing compound biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a xanthone-containing compound." [GOC:di] +synonym: "xanthone biosynthesis" NARROW [CHEBI:37647] +synonym: "xanthone biosynthetic process" NARROW [CHEBI:37647] +synonym: "xanthone-containing compound anabolism" EXACT [GOC:obol] +synonym: "xanthone-containing compound biosynthesis" EXACT [GOC:obol] +synonym: "xanthone-containing compound formation" EXACT [GOC:obol] +synonym: "xanthone-containing compound synthesis" EXACT [GOC:obol] +synonym: "xanthones anabolism" EXACT [GOC:obol] +synonym: "xanthones biosynthesis" EXACT [GOC:obol] +synonym: "xanthones biosynthetic process" EXACT [GOC:obol] +synonym: "xanthones formation" EXACT [GOC:obol] +synonym: "xanthones synthesis" EXACT [GOC:obol] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:2001305 ! xanthone-containing compound metabolic process +created_by: bf +creation_date: 2012-03-14T10:35:44Z + +[Term] +id: GO:2001308 +name: gliotoxin metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi." [PMID:16333108, PMID:17574915, PMID:18272357] +synonym: "gliotoxin metabolism" EXACT [GOC:obol] +is_a: GO:0006518 ! peptide metabolic process +is_a: GO:0006790 ! sulfur compound metabolic process +is_a: GO:0016999 ! antibiotic metabolic process +is_a: GO:0043385 ! mycotoxin metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: pr +creation_date: 2012-03-15T03:42:10Z + +[Term] +id: GO:2001309 +name: gliotoxin catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi." [GOC:di, PMID:16333108, PMID:17574915, PMID:18272357] +synonym: "gliotoxin breakdown" EXACT [GOC:obol] +synonym: "gliotoxin catabolism" EXACT [GOC:obol] +synonym: "gliotoxin degradation" EXACT [GOC:obol] +is_a: GO:0017001 ! antibiotic catabolic process +is_a: GO:0042737 ! drug catabolic process +is_a: GO:0043171 ! peptide catabolic process +is_a: GO:0043387 ! mycotoxin catabolic process +is_a: GO:0044273 ! sulfur compound catabolic process +is_a: GO:0046700 ! heterocycle catabolic process +is_a: GO:0051410 ! detoxification of nitrogen compound +is_a: GO:1901361 ! organic cyclic compound catabolic process +is_a: GO:2001308 ! gliotoxin metabolic process +created_by: pr +creation_date: 2012-03-15T03:42:14Z + +[Term] +id: GO:2001310 +name: gliotoxin biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi." [GOC:di, PMID:16333108, PMID:17574915, PMID:18272357, PMID:29966253] +synonym: "gliotoxin anabolism" EXACT [GOC:obol] +synonym: "gliotoxin biosynthesis" EXACT [GOC:obol] +synonym: "gliotoxin formation" EXACT [GOC:obol] +synonym: "gliotoxin synthesis" EXACT [GOC:obol] +is_a: GO:0009072 ! aromatic amino acid family metabolic process +is_a: GO:0017000 ! antibiotic biosynthetic process +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0043043 ! peptide biosynthetic process +is_a: GO:0043386 ! mycotoxin biosynthetic process +is_a: GO:0044272 ! sulfur compound biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:1901605 ! alpha-amino acid metabolic process +is_a: GO:2001308 ! gliotoxin metabolic process +relationship: has_part GO:0003839 ! gamma-glutamylcyclotransferase activity +relationship: has_part GO:0004364 ! glutathione transferase activity +relationship: has_part GO:0004497 ! monooxygenase activity +relationship: has_part GO:0008170 ! N-methyltransferase activity +relationship: has_part GO:0008483 ! transaminase activity +created_by: pr +creation_date: 2012-03-15T03:42:18Z + +[Term] +id: GO:2001311 +name: lysobisphosphatidic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group." [GOC:mw] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate metabolic process" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate metabolism" EXACT [GOC:obol] +synonym: "LBPA metabolic process" EXACT [GOC:obol] +synonym: "LBPA metabolism" EXACT [GOC:obol] +synonym: "lysobisphosphatidic acid metabolism" EXACT [GOC:obol] +is_a: GO:0006650 ! glycerophospholipid metabolic process +is_a: GO:0052646 ! alditol phosphate metabolic process +created_by: bf +creation_date: 2012-03-16T09:31:27Z + +[Term] +id: GO:2001312 +name: lysobisphosphatidic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group." [GOC:mw] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) anabolism" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthesis" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthetic process" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) formation" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate (BMP) synthesis" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate anabolism" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate biosynthesis" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate biosynthetic process" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate formation" EXACT [GOC:obol] +synonym: "bis(monoacylglycerol) hydrogen phosphate synthesis" EXACT [GOC:obol] +synonym: "LBPA anabolism" EXACT [GOC:obol] +synonym: "LBPA biosynthesis" EXACT [GOC:obol] +synonym: "LBPA biosynthetic process" EXACT [GOC:obol] +synonym: "LBPA formation" EXACT [GOC:obol] +synonym: "LBPA synthesis" EXACT [GOC:obol] +synonym: "lysobisphosphatidic acid anabolism" EXACT [GOC:obol] +synonym: "lysobisphosphatidic acid biosynthesis" EXACT [GOC:obol] +synonym: "lysobisphosphatidic acid formation" EXACT [GOC:obol] +synonym: "lysobisphosphatidic acid synthesis" EXACT [GOC:obol] +is_a: GO:0046474 ! glycerophospholipid biosynthetic process +is_a: GO:1901137 ! carbohydrate derivative biosynthetic process +is_a: GO:2001311 ! lysobisphosphatidic acid metabolic process +created_by: bf +creation_date: 2012-03-16T09:31:31Z + +[Term] +id: GO:2001313 +name: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose." [GOC:yaf] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolism" EXACT [GOC:obol] +is_a: GO:0006040 ! amino sugar metabolic process +is_a: GO:0006793 ! phosphorus metabolic process +is_a: GO:0009225 ! nucleotide-sugar metabolic process +created_by: pr +creation_date: 2012-03-22T01:19:54Z + +[Term] +id: GO:2001314 +name: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose." [GOC:yaf] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose breakdown" EXACT [GOC:obol] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolism" EXACT [GOC:obol] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose degradation" EXACT [GOC:obol] +is_a: GO:0009227 ! nucleotide-sugar catabolic process +is_a: GO:0046348 ! amino sugar catabolic process +is_a: GO:2001313 ! UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process +created_by: pr +creation_date: 2012-03-22T01:20:01Z + +[Term] +id: GO:2001315 +name: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose." [GOC:yaf, UniPathway:UPA00032] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose anabolism" EXACT [GOC:obol] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthesis" EXACT [GOC:obol] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose formation" EXACT [GOC:obol] +synonym: "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose synthesis" EXACT [GOC:obol] +is_a: GO:0009226 ! nucleotide-sugar biosynthetic process +is_a: GO:0046349 ! amino sugar biosynthetic process +is_a: GO:2001313 ! UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process +created_by: pr +creation_date: 2012-03-22T01:20:05Z + +[Term] +id: GO:2001316 +name: kojic acid metabolic process +namespace: biological_process +def: "The chemical reactions and pathways involving kojic acid." [GOC:di] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolic process" EXACT [GOC:obol] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolism" EXACT [GOC:obol] +synonym: "C6H6O4 metabolic process" RELATED [GOC:obol] +synonym: "C6H6O4 metabolism" RELATED [GOC:obol] +synonym: "kojic acid metabolism" EXACT [GOC:obol] +is_a: GO:0034308 ! primary alcohol metabolic process +is_a: GO:0042180 ! cellular ketone metabolic process +is_a: GO:0046483 ! heterocycle metabolic process +is_a: GO:1901360 ! organic cyclic compound metabolic process +created_by: bf +creation_date: 2012-04-18T09:22:42Z + +[Term] +id: GO:2001317 +name: kojic acid biosynthetic process +namespace: biological_process +def: "The chemical reactions and pathways resulting in the formation of kojic acid." [GOC:di] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism" EXACT [GOC:obol] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis" EXACT [GOC:obol] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process" EXACT [GOC:obol] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation" EXACT [GOC:obol] +synonym: "5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis" EXACT [GOC:obol] +synonym: "C6H6O4 anabolism" RELATED [GOC:obol] +synonym: "C6H6O4 biosynthesis" RELATED [GOC:obol] +synonym: "C6H6O4 biosynthetic process" RELATED [GOC:obol] +synonym: "C6H6O4 formation" RELATED [GOC:obol] +synonym: "C6H6O4 synthesis" RELATED [GOC:obol] +synonym: "kojic acid anabolism" EXACT [GOC:obol] +synonym: "kojic acid biosynthesis" EXACT [GOC:obol] +synonym: "kojic acid formation" EXACT [GOC:obol] +synonym: "kojic acid synthesis" EXACT [GOC:obol] +is_a: GO:0018130 ! heterocycle biosynthetic process +is_a: GO:0034309 ! primary alcohol biosynthetic process +is_a: GO:0042181 ! ketone biosynthetic process +is_a: GO:1901362 ! organic cyclic compound biosynthetic process +is_a: GO:2001316 ! kojic acid metabolic process +created_by: bf +creation_date: 2012-04-18T09:22:46Z + +[Typedef] +id: ends_during +name: ends_during +namespace: external +xref: RO:0002093 + +[Typedef] +id: happens_during +name: happens during +namespace: external +xref: RO:0002092 +is_transitive: true +is_a: ends_during ! ends_during + +[Typedef] +id: has_part +name: has part +namespace: external +xref: BFO:0000051 +is_transitive: true + +[Typedef] +id: negatively_regulates +name: negatively regulates +namespace: external +xref: RO:0002212 +is_a: regulates ! regulates + +[Typedef] +id: occurs_in +name: occurs in +namespace: external +xref: BFO:0000066 +transitive_over: part_of ! part of + +[Typedef] +id: part_of +name: part of +namespace: external +xref: BFO:0000050 +is_transitive: true +inverse_of: has_part ! has part + +[Typedef] +id: positively_regulates +name: positively regulates +namespace: external +xref: RO:0002213 +holds_over_chain: negatively_regulates negatively_regulates +is_a: regulates ! regulates + +[Typedef] +id: regulates +name: regulates +namespace: external +xref: RO:0002211 +is_transitive: true + +[Typedef] +id: starts_during +name: starts_during +namespace: external +xref: RO:0002091 + +[Typedef] +id: term_tracker_item +name: term tracker item +namespace: external +xref: IAO:0000233 +is_metadata_tag: true +is_class_level: true + diff --git a/resources/hs_ncbi_genes.tsv b/resources/hs_ncbi_genes.tsv new file mode 100644 index 0000000..99752d5 --- /dev/null +++ b/resources/hs_ncbi_genes.tsv @@ -0,0 +1,60088 @@ +GeneID Symbol dbXrefs +1 A1BG MIM:138670|HGNC:HGNC:5|Ensembl:ENSG00000121410|Vega:OTTHUMG00000183507 +2 A2M MIM:103950|HGNC:HGNC:7|Ensembl:ENSG00000175899|Vega:OTTHUMG00000150267 +3 A2MP1 HGNC:HGNC:8|Ensembl:ENSG00000256069 +9 NAT1 MIM:108345|HGNC:HGNC:7645|Ensembl:ENSG00000171428|Vega:OTTHUMG00000097001 +10 NAT2 MIM:612182|HGNC:HGNC:7646|Ensembl:ENSG00000156006|Vega:OTTHUMG00000130826 +11 NATP HGNC:HGNC:15 +12 SERPINA3 MIM:107280|HGNC:HGNC:16|Ensembl:ENSG00000196136|Vega:OTTHUMG00000029851 +13 AADAC MIM:600338|HGNC:HGNC:17|Ensembl:ENSG00000114771|Vega:OTTHUMG00000159876 +14 AAMP MIM:603488|HGNC:HGNC:18|Ensembl:ENSG00000127837|Vega:OTTHUMG00000155202 +15 AANAT MIM:600950|HGNC:HGNC:19|Ensembl:ENSG00000129673|Vega:OTTHUMG00000180179 +16 AARS MIM:601065|HGNC:HGNC:20|Ensembl:ENSG00000090861|Vega:OTTHUMG00000177042 +17 AAVS1 MIM:102699|HGNC:HGNC:22 +18 ABAT MIM:137150|HGNC:HGNC:23|Ensembl:ENSG00000183044|Vega:OTTHUMG00000048201 +19 ABCA1 MIM:600046|HGNC:HGNC:29|Ensembl:ENSG00000165029|Vega:OTTHUMG00000020417 +20 ABCA2 MIM:600047|HGNC:HGNC:32|Ensembl:ENSG00000107331|Vega:OTTHUMG00000020958 +21 ABCA3 MIM:601615|HGNC:HGNC:33|Ensembl:ENSG00000167972|Vega:OTTHUMG00000128845 +22 ABCB7 MIM:300135|HGNC:HGNC:48|Ensembl:ENSG00000131269|Vega:OTTHUMG00000021862 +23 ABCF1 MIM:603429|HGNC:HGNC:70|Ensembl:ENSG00000204574|Vega:OTTHUMG00000031094 +24 ABCA4 MIM:601691|HGNC:HGNC:34|Ensembl:ENSG00000198691|Vega:OTTHUMG00000010622 +25 ABL1 MIM:189980|HGNC:HGNC:76|Ensembl:ENSG00000097007|Vega:OTTHUMG00000020813 +26 AOC1 MIM:104610|HGNC:HGNC:80|Ensembl:ENSG00000002726|Vega:OTTHUMG00000158306 +27 ABL2 MIM:164690|HGNC:HGNC:77|Ensembl:ENSG00000143322|Vega:OTTHUMG00000035199 +28 ABO MIM:110300|HGNC:HGNC:79|Ensembl:ENSG00000175164 +29 ABR MIM:600365|HGNC:HGNC:81|Ensembl:ENSG00000159842|Vega:OTTHUMG00000090313 +30 ACAA1 MIM:604054|HGNC:HGNC:82|Ensembl:ENSG00000060971|Vega:OTTHUMG00000131087 +31 ACACA MIM:200350|HGNC:HGNC:84|Ensembl:ENSG00000278540|Vega:OTTHUMG00000188463 +32 ACACB MIM:601557|HGNC:HGNC:85|Ensembl:ENSG00000076555|Vega:OTTHUMG00000169250 +33 ACADL MIM:609576|HGNC:HGNC:88|Ensembl:ENSG00000115361|Vega:OTTHUMG00000132989 +34 ACADM MIM:607008|HGNC:HGNC:89|Ensembl:ENSG00000117054|Vega:OTTHUMG00000009784 +35 ACADS MIM:606885|HGNC:HGNC:90|Ensembl:ENSG00000122971|Vega:OTTHUMG00000169203 +36 ACADSB MIM:600301|HGNC:HGNC:91|Ensembl:ENSG00000196177|Vega:OTTHUMG00000019200 +37 ACADVL MIM:609575|HGNC:HGNC:92|Ensembl:ENSG00000072778|Vega:OTTHUMG00000102157 +38 ACAT1 MIM:607809|HGNC:HGNC:93|Ensembl:ENSG00000075239|Vega:OTTHUMG00000166381 +39 ACAT2 MIM:100678|HGNC:HGNC:94|Ensembl:ENSG00000120437|Vega:OTTHUMG00000015935 +40 ASIC2 MIM:601784|HGNC:HGNC:99|Ensembl:ENSG00000108684|Vega:OTTHUMG00000132885 +41 ASIC1 MIM:602866|HGNC:HGNC:100|Ensembl:ENSG00000110881|Vega:OTTHUMG00000169812 +43 ACHE MIM:100740|HGNC:HGNC:108|Ensembl:ENSG00000087085|Vega:OTTHUMG00000157033 +46 ACLS MIM:200990|HGNC:HGNC:114 +47 ACLY MIM:108728|HGNC:HGNC:115|Ensembl:ENSG00000131473|Vega:OTTHUMG00000133507 +48 ACO1 MIM:100880|HGNC:HGNC:117|Ensembl:ENSG00000122729|Vega:OTTHUMG00000019740 +49 ACR MIM:102480|HGNC:HGNC:126|Ensembl:ENSG00000100312|Vega:OTTHUMG00000150155 +50 ACO2 MIM:100850|HGNC:HGNC:118|Ensembl:ENSG00000100412|Vega:OTTHUMG00000030544 +51 ACOX1 MIM:609751|HGNC:HGNC:119|Ensembl:ENSG00000161533|Vega:OTTHUMG00000180027 +52 ACP1 MIM:171500|HGNC:HGNC:122|Ensembl:ENSG00000143727|Vega:OTTHUMG00000086933 +53 ACP2 MIM:171650|HGNC:HGNC:123|Ensembl:ENSG00000134575|Vega:OTTHUMG00000166949 +54 ACP5 MIM:171640|HGNC:HGNC:124|Ensembl:ENSG00000102575|Vega:OTTHUMG00000182036 +55 ACPP MIM:171790|HGNC:HGNC:125|Ensembl:ENSG00000014257|Vega:OTTHUMG00000159650 +56 ACRV1 MIM:102525|HGNC:HGNC:127|Ensembl:ENSG00000134940|Vega:OTTHUMG00000165854 +58 ACTA1 MIM:102610|HGNC:HGNC:129|Ensembl:ENSG00000143632|Vega:OTTHUMG00000038006 +59 ACTA2 MIM:102620|HGNC:HGNC:130|Ensembl:ENSG00000107796|Vega:OTTHUMG00000018700 +60 ACTB MIM:102630|HGNC:HGNC:132|Ensembl:ENSG00000075624|Vega:OTTHUMG00000023268 +62 ACTBP2 HGNC:HGNC:135 +63 ACTBP3 HGNC:HGNC:136 +64 ACTBP4 HGNC:HGNC:137 +66 ACTBP6 HGNC:HGNC:139 +67 ACTBP7 HGNC:HGNC:140 +68 ACTBP8 HGNC:HGNC:141 +69 ACTBP9 HGNC:HGNC:142 +70 ACTC1 MIM:102540|HGNC:HGNC:143|Ensembl:ENSG00000159251|Vega:OTTHUMG00000129675 +71 ACTG1 MIM:102560|HGNC:HGNC:144|Ensembl:ENSG00000184009|Vega:OTTHUMG00000177955 +72 ACTG2 MIM:102545|HGNC:HGNC:145|Ensembl:ENSG00000163017|Vega:OTTHUMG00000129813 +73 ACTG1P1 HGNC:HGNC:146 +74 ACTG1P2 HGNC:HGNC:147 +75 ACTG1P3 HGNC:HGNC:148 +78 ACTG1P6 HGNC:HGNC:151 +79 ACTG1P7 HGNC:HGNC:152 +80 ACTG1P8 HGNC:HGNC:153 +81 ACTN4 MIM:604638|HGNC:HGNC:166|Ensembl:ENSG00000130402|Vega:OTTHUMG00000137382 +82 ACTG1P9 HGNC:HGNC:154 +83 ACTG1P10 HGNC:HGNC:155 +86 ACTL6A MIM:604958|HGNC:HGNC:24124|Ensembl:ENSG00000136518|Vega:OTTHUMG00000157782 +87 ACTN1 MIM:102575|HGNC:HGNC:163|Ensembl:ENSG00000072110|Vega:OTTHUMG00000171386 +88 ACTN2 MIM:102573|HGNC:HGNC:164|Ensembl:ENSG00000077522|Vega:OTTHUMG00000040059 +89 ACTN3 MIM:102574|HGNC:HGNC:165|Ensembl:ENSG00000248746|Vega:OTTHUMG00000160815 +90 ACVR1 MIM:102576|HGNC:HGNC:171|Ensembl:ENSG00000115170|Vega:OTTHUMG00000131967 +91 ACVR1B MIM:601300|HGNC:HGNC:172|Ensembl:ENSG00000135503|Vega:OTTHUMG00000167920 +92 ACVR2A MIM:102581|HGNC:HGNC:173|Ensembl:ENSG00000121989|Vega:OTTHUMG00000150603 +93 ACVR2B MIM:602730|HGNC:HGNC:174|Ensembl:ENSG00000114739|Vega:OTTHUMG00000131291 +94 ACVRL1 MIM:601284|HGNC:HGNC:175|Ensembl:ENSG00000139567|Vega:OTTHUMG00000169507 +95 ACY1 MIM:104620|HGNC:HGNC:177|Ensembl:ENSG00000243989|Vega:OTTHUMG00000157815 +97 ACYP1 MIM:600875|HGNC:HGNC:179|Ensembl:ENSG00000119640|Vega:OTTHUMG00000171767 +98 ACYP2 MIM:102595|HGNC:HGNC:180|Ensembl:ENSG00000170634|Vega:OTTHUMG00000129287 +100 ADA MIM:608958|HGNC:HGNC:186|Ensembl:ENSG00000196839|Vega:OTTHUMG00000033081 +101 ADAM8 MIM:602267|HGNC:HGNC:215|Ensembl:ENSG00000151651|Vega:OTTHUMG00000019309 +102 ADAM10 MIM:602192|HGNC:HGNC:188|Ensembl:ENSG00000137845|Vega:OTTHUMG00000132633 +103 ADAR MIM:146920|HGNC:HGNC:225|Ensembl:ENSG00000160710|Vega:OTTHUMG00000037261 +104 ADARB1 MIM:601218|HGNC:HGNC:226|Ensembl:ENSG00000197381|Vega:OTTHUMG00000090295 +105 ADARB2 MIM:602065|HGNC:HGNC:227|Ensembl:ENSG00000185736|Vega:OTTHUMG00000017543 +106 ADCP1 HGNC:HGNC:229 +107 ADCY1 MIM:103072|HGNC:HGNC:232|Ensembl:ENSG00000164742|Vega:OTTHUMG00000155420 +108 ADCY2 MIM:103071|HGNC:HGNC:233|Ensembl:ENSG00000078295|Vega:OTTHUMG00000090476 +109 ADCY3 MIM:600291|HGNC:HGNC:234|Ensembl:ENSG00000138031|Vega:OTTHUMG00000094765 +111 ADCY5 MIM:600293|HGNC:HGNC:236|Ensembl:ENSG00000173175|Vega:OTTHUMG00000159517 +112 ADCY6 MIM:600294|HGNC:HGNC:237|Ensembl:ENSG00000174233|Vega:OTTHUMG00000170396 +113 ADCY7 MIM:600385|HGNC:HGNC:238|Ensembl:ENSG00000121281|Vega:OTTHUMG00000133172 +114 ADCY8 MIM:103070|HGNC:HGNC:239|Ensembl:ENSG00000155897|Vega:OTTHUMG00000164756 +115 ADCY9 MIM:603302|HGNC:HGNC:240|Ensembl:ENSG00000162104|Vega:OTTHUMG00000177612 +116 ADCYAP1 MIM:102980|HGNC:HGNC:241|Ensembl:ENSG00000141433|Vega:OTTHUMG00000131479 +117 ADCYAP1R1 MIM:102981|HGNC:HGNC:242|Ensembl:ENSG00000078549|Vega:OTTHUMG00000023884 +118 ADD1 MIM:102680|HGNC:HGNC:243|Ensembl:ENSG00000087274|Vega:OTTHUMG00000122080 +119 ADD2 MIM:102681|HGNC:HGNC:244|Ensembl:ENSG00000075340|Vega:OTTHUMG00000129710 +120 ADD3 MIM:601568|HGNC:HGNC:245|Ensembl:ENSG00000148700|Vega:OTTHUMG00000019032 +122 ADFN MIM:300700|HGNC:HGNC:247 +123 PLIN2 MIM:103195|HGNC:HGNC:248|Ensembl:ENSG00000147872|Vega:OTTHUMG00000019624 +124 ADH1A MIM:103700|HGNC:HGNC:249|Ensembl:ENSG00000187758|Vega:OTTHUMG00000131026 +125 ADH1B MIM:103720|HGNC:HGNC:250|Ensembl:ENSG00000196616|Vega:OTTHUMG00000161413 +126 ADH1C MIM:103730|HGNC:HGNC:251|Ensembl:ENSG00000248144|Vega:OTTHUMG00000161422 +127 ADH4 MIM:103740|HGNC:HGNC:252|Ensembl:ENSG00000198099|Vega:OTTHUMG00000161227 +128 ADH5 MIM:103710|HGNC:HGNC:253|Ensembl:ENSG00000197894|Vega:OTTHUMG00000161230 +130 ADH6 MIM:103735|HGNC:HGNC:255|Ensembl:ENSG00000172955|Vega:OTTHUMG00000131024 +131 ADH7 MIM:600086|HGNC:HGNC:256|Ensembl:ENSG00000196344|Vega:OTTHUMG00000159318 +132 ADK MIM:102750|HGNC:HGNC:257|Ensembl:ENSG00000156110|Vega:OTTHUMG00000018506 +133 ADM MIM:103275|HGNC:HGNC:259|Ensembl:ENSG00000148926|Vega:OTTHUMG00000165907 +134 ADORA1 MIM:102775|HGNC:HGNC:262|Ensembl:ENSG00000163485|Vega:OTTHUMG00000042125 +135 ADORA2A MIM:102776|HGNC:HGNC:263|Ensembl:ENSG00000128271|Vega:OTTHUMG00000150761 +136 ADORA2B MIM:600446|HGNC:HGNC:264|Ensembl:ENSG00000170425|Vega:OTTHUMG00000059140 +137 ADORA2BP1 HGNC:HGNC:265 +140 ADORA3 MIM:600445|HGNC:HGNC:268|Ensembl:ENSG00000282608|Vega:OTTHUMG00000011957 +141 ADPRH MIM:603081|HGNC:HGNC:269|Ensembl:ENSG00000144843|Vega:OTTHUMG00000159420 +142 PARP1 MIM:173870|HGNC:HGNC:270|Ensembl:ENSG00000143799|Vega:OTTHUMG00000037556 +143 PARP4 MIM:607519|HGNC:HGNC:271|Ensembl:ENSG00000102699|Vega:OTTHUMG00000016582 +144 PARP1P1 HGNC:HGNC:275 +145 PARP1P2 HGNC:HGNC:276 +146 ADRA1D MIM:104219|HGNC:HGNC:280|Ensembl:ENSG00000171873|Vega:OTTHUMG00000031779 +147 ADRA1B MIM:104220|HGNC:HGNC:278|Ensembl:ENSG00000170214|Vega:OTTHUMG00000130327 +148 ADRA1A MIM:104221|HGNC:HGNC:277|Ensembl:ENSG00000120907|Vega:OTTHUMG00000099459 +150 ADRA2A MIM:104210|HGNC:HGNC:281|Ensembl:ENSG00000150594|Vega:OTTHUMG00000019050 +151 ADRA2B MIM:104260|HGNC:HGNC:282|Ensembl:ENSG00000274286|Vega:OTTHUMG00000188276 +152 ADRA2C MIM:104250|HGNC:HGNC:283|Ensembl:ENSG00000184160|Vega:OTTHUMG00000159830 +153 ADRB1 MIM:109630|HGNC:HGNC:285|Ensembl:ENSG00000043591|Vega:OTTHUMG00000019079 +154 ADRB2 MIM:109690|HGNC:HGNC:286|Ensembl:ENSG00000169252|Vega:OTTHUMG00000129933 +155 ADRB3 MIM:109691|HGNC:HGNC:288|Ensembl:ENSG00000188778|Vega:OTTHUMG00000164028 +156 GRK2 MIM:109635|HGNC:HGNC:289|Ensembl:ENSG00000173020|Vega:OTTHUMG00000167104 +157 GRK3 MIM:109636|HGNC:HGNC:290|Ensembl:ENSG00000100077|Vega:OTTHUMG00000150280 +158 ADSL MIM:608222|HGNC:HGNC:291|Ensembl:ENSG00000239900|Vega:OTTHUMG00000166425 +159 ADSS MIM:103060|HGNC:HGNC:292|Ensembl:ENSG00000035687|Vega:OTTHUMG00000040102 +160 AP2A1 MIM:601026|HGNC:HGNC:561|Ensembl:ENSG00000196961|Vega:OTTHUMG00000183253 +161 AP2A2 MIM:607242|HGNC:HGNC:562|Ensembl:ENSG00000183020|Vega:OTTHUMG00000165627 +162 AP1B1 MIM:600157|HGNC:HGNC:554|Ensembl:ENSG00000100280|Vega:OTTHUMG00000151109 +163 AP2B1 MIM:601025|HGNC:HGNC:563|Ensembl:ENSG00000006125|Vega:OTTHUMG00000179924 +164 AP1G1 MIM:603533|HGNC:HGNC:555|Ensembl:ENSG00000166747|Vega:OTTHUMG00000176871 +165 AEBP1 MIM:602981|HGNC:HGNC:303|Ensembl:ENSG00000106624|Vega:OTTHUMG00000023362 +166 AES MIM:600188|HGNC:HGNC:307|Ensembl:ENSG00000104964|Vega:OTTHUMG00000180567 +167 CRISP1 MIM:601193|HGNC:HGNC:304|Ensembl:ENSG00000124812|Vega:OTTHUMG00000014827 +169 AF8T MIM:116950|HGNC:HGNC:309 +170 AFA MIM:106250|HGNC:HGNC:310 +171 AFD1 MIM:154400|HGNC:HGNC:312 +172 AFG3L1P MIM:603020|HGNC:HGNC:314|Ensembl:ENSG00000223959 +173 AFM MIM:104145|HGNC:HGNC:316|Ensembl:ENSG00000079557|Vega:OTTHUMG00000130004 +174 AFP MIM:104150|HGNC:HGNC:317|Ensembl:ENSG00000081051|Vega:OTTHUMG00000130011 +175 AGA MIM:613228|HGNC:HGNC:318|Ensembl:ENSG00000038002|Vega:OTTHUMG00000160723 +176 ACAN MIM:155760|HGNC:HGNC:319|Ensembl:ENSG00000157766|Vega:OTTHUMG00000171989 +177 AGER MIM:600214|HGNC:HGNC:320|Ensembl:ENSG00000204305|Vega:OTTHUMG00000031120 +178 AGL MIM:610860|HGNC:HGNC:321|Ensembl:ENSG00000162688|Vega:OTTHUMG00000010803 +179 AGMX2 MIM:300310|HGNC:HGNC:323 +181 AGRP MIM:602311|HGNC:HGNC:330|Ensembl:ENSG00000159723|Vega:OTTHUMG00000137509 +182 JAG1 MIM:601920|HGNC:HGNC:6188|Ensembl:ENSG00000101384|Vega:OTTHUMG00000031872 +183 AGT MIM:106150|HGNC:HGNC:333|Ensembl:ENSG00000135744|Vega:OTTHUMG00000037757 +185 AGTR1 MIM:106165|HGNC:HGNC:336|Ensembl:ENSG00000144891|Vega:OTTHUMG00000159503 +186 AGTR2 MIM:300034|HGNC:HGNC:338|Ensembl:ENSG00000180772|Vega:OTTHUMG00000022243 +187 APLNR MIM:600052|HGNC:HGNC:339|Ensembl:ENSG00000134817|Vega:OTTHUMG00000167021 +189 AGXT MIM:604285|HGNC:HGNC:341|Ensembl:ENSG00000172482|Vega:OTTHUMG00000133354 +190 NR0B1 MIM:300473|HGNC:HGNC:7960|Ensembl:ENSG00000169297|Vega:OTTHUMG00000021323 +191 AHCY MIM:180960|HGNC:HGNC:343|Ensembl:ENSG00000101444|Vega:OTTHUMG00000140098 +192 AIC MIM:304050|HGNC:HGNC:350 +196 AHR MIM:600253|HGNC:HGNC:348|Ensembl:ENSG00000106546|Ensembl:ENSG00000283321|Vega:OTTHUMG00000149967|Vega:OTTHUMG00000191686 +197 AHSG MIM:138680|HGNC:HGNC:349|Ensembl:ENSG00000145192|Vega:OTTHUMG00000156605 +199 AIF1 MIM:601833|HGNC:HGNC:352|Ensembl:ENSG00000204472|Vega:OTTHUMG00000031246 +201 AIH3 MIM:301201|HGNC:HGNC:355 +202 CRYBG1 MIM:601797|HGNC:HGNC:356|Ensembl:ENSG00000112297|Vega:OTTHUMG00000015302 +203 AK1 MIM:103000|HGNC:HGNC:361|Ensembl:ENSG00000106992|Vega:OTTHUMG00000020722 +204 AK2 MIM:103020|HGNC:HGNC:362|Ensembl:ENSG00000004455|Vega:OTTHUMG00000004131 +205 AK4 MIM:103030|HGNC:HGNC:363|Ensembl:ENSG00000162433|Vega:OTTHUMG00000009033 +206 AK4P1 HGNC:HGNC:364 +207 AKT1 MIM:164730|HGNC:HGNC:391|Ensembl:ENSG00000142208|Vega:OTTHUMG00000170795 +208 AKT2 MIM:164731|HGNC:HGNC:392|Ensembl:ENSG00000105221|Vega:OTTHUMG00000137375 +210 ALAD MIM:125270|HGNC:HGNC:395|Ensembl:ENSG00000148218|Vega:OTTHUMG00000020522 +211 ALAS1 MIM:125290|HGNC:HGNC:396|Ensembl:ENSG00000023330|Vega:OTTHUMG00000158108 +212 ALAS2 MIM:301300|HGNC:HGNC:397|Ensembl:ENSG00000158578|Vega:OTTHUMG00000021641 +213 ALB MIM:103600|HGNC:HGNC:399|Ensembl:ENSG00000163631|Vega:OTTHUMG00000129919 +214 ALCAM MIM:601662|HGNC:HGNC:400|Ensembl:ENSG00000170017|Vega:OTTHUMG00000159192 +215 ABCD1 MIM:300371|HGNC:HGNC:61|Ensembl:ENSG00000101986|Vega:OTTHUMG00000024215 +216 ALDH1A1 MIM:100640|HGNC:HGNC:402|Ensembl:ENSG00000165092|Vega:OTTHUMG00000020019 +217 ALDH2 MIM:100650|HGNC:HGNC:404|Ensembl:ENSG00000111275|Vega:OTTHUMG00000169603 +218 ALDH3A1 MIM:100660|HGNC:HGNC:405|Ensembl:ENSG00000108602|Vega:OTTHUMG00000059469 +219 ALDH1B1 MIM:100670|HGNC:HGNC:407|Ensembl:ENSG00000137124|Vega:OTTHUMG00000019938 +220 ALDH1A3 MIM:600463|HGNC:HGNC:409|Ensembl:ENSG00000184254|Vega:OTTHUMG00000186439 +221 ALDH3B1 MIM:600466|HGNC:HGNC:410|Ensembl:ENSG00000006534|Vega:OTTHUMG00000154910 +222 ALDH3B2 MIM:601917|HGNC:HGNC:411|Ensembl:ENSG00000132746|Vega:OTTHUMG00000167284 +223 ALDH9A1 MIM:602733|HGNC:HGNC:412|Ensembl:ENSG00000143149|Vega:OTTHUMG00000034677 +224 ALDH3A2 MIM:609523|HGNC:HGNC:403|Ensembl:ENSG00000072210|Vega:OTTHUMG00000059471 +225 ABCD2 MIM:601081|HGNC:HGNC:66|Ensembl:ENSG00000173208|Vega:OTTHUMG00000169337 +226 ALDOA MIM:103850|HGNC:HGNC:414|Ensembl:ENSG00000149925|Vega:OTTHUMG00000132107 +228 ALDOAP2 HGNC:HGNC:416 +229 ALDOB MIM:612724|HGNC:HGNC:417|Ensembl:ENSG00000136872|Vega:OTTHUMG00000020378 +230 ALDOC MIM:103870|HGNC:HGNC:418|Ensembl:ENSG00000109107|Vega:OTTHUMG00000132605 +231 AKR1B1 MIM:103880|HGNC:HGNC:381|Ensembl:ENSG00000085662|Vega:OTTHUMG00000155322 +236 AKR1B1P2 HGNC:HGNC:425 +238 ALK MIM:105590|HGNC:HGNC:427|Ensembl:ENSG00000171094|Vega:OTTHUMG00000152034 +239 ALOX12 MIM:152391|HGNC:HGNC:429|Ensembl:ENSG00000108839|Vega:OTTHUMG00000102088 +240 ALOX5 MIM:152390|HGNC:HGNC:435|Ensembl:ENSG00000012779|Vega:OTTHUMG00000018081 +241 ALOX5AP MIM:603700|HGNC:HGNC:436|Ensembl:ENSG00000132965|Vega:OTTHUMG00000016677 +242 ALOX12B MIM:603741|HGNC:HGNC:430|Ensembl:ENSG00000179477|Vega:OTTHUMG00000108180 +243 ALOX12P1 HGNC:HGNC:431 +245 ALOX12P2 HGNC:HGNC:432|Ensembl:ENSG00000262943 +246 ALOX15 MIM:152392|HGNC:HGNC:433|Ensembl:ENSG00000161905|Vega:OTTHUMG00000090746 +247 ALOX15B MIM:603697|HGNC:HGNC:434|Ensembl:ENSG00000179593|Vega:OTTHUMG00000108181 +248 ALPI MIM:171740|HGNC:HGNC:437|Ensembl:ENSG00000163295|Vega:OTTHUMG00000133258 +249 ALPL MIM:171760|HGNC:HGNC:438|Ensembl:ENSG00000162551|Vega:OTTHUMG00000002949 +250 ALPP MIM:171800|HGNC:HGNC:439|Ensembl:ENSG00000163283|Vega:OTTHUMG00000133255 +251 ALPPL2 MIM:171810|HGNC:HGNC:441|Ensembl:ENSG00000163286|Vega:OTTHUMG00000133257 +253 ALS3 MIM:606640|HGNC:HGNC:444 +255 ALS5 MIM:602099|HGNC:HGNC:446 +257 ALX3 MIM:606014|HGNC:HGNC:449|Ensembl:ENSG00000156150|Vega:OTTHUMG00000011650 +258 AMBN MIM:601259|HGNC:HGNC:452|Ensembl:ENSG00000178522|Vega:OTTHUMG00000129913 +259 AMBP MIM:176870|HGNC:HGNC:453|Ensembl:ENSG00000106927|Vega:OTTHUMG00000020534 +261 AMCN MIM:208100|HGNC:HGNC:456 +262 AMD1 MIM:180980|HGNC:HGNC:457|Ensembl:ENSG00000123505|Vega:OTTHUMG00000015369 +263 AMD1P2 HGNC:HGNC:460 +265 AMELX MIM:300391|HGNC:HGNC:461|Ensembl:ENSG00000125363|Vega:OTTHUMG00000021130 +266 AMELY MIM:410000|HGNC:HGNC:462|Ensembl:ENSG00000099721|Vega:OTTHUMG00000035297 +267 AMFR MIM:603243|HGNC:HGNC:463|Ensembl:ENSG00000159461|Vega:OTTHUMG00000133239 +268 AMH MIM:600957|HGNC:HGNC:464|Ensembl:ENSG00000104899|Vega:OTTHUMG00000180415 +269 AMHR2 MIM:600956|HGNC:HGNC:465|Ensembl:ENSG00000135409|Vega:OTTHUMG00000170048 +270 AMPD1 MIM:102770|HGNC:HGNC:468|Ensembl:ENSG00000116748|Vega:OTTHUMG00000011892 +271 AMPD2 MIM:102771|HGNC:HGNC:469|Ensembl:ENSG00000116337|Vega:OTTHUMG00000011649 +272 AMPD3 MIM:102772|HGNC:HGNC:470|Ensembl:ENSG00000133805|Vega:OTTHUMG00000165682 +273 AMPH MIM:600418|HGNC:HGNC:471|Ensembl:ENSG00000078053|Vega:OTTHUMG00000023725 +274 BIN1 MIM:601248|HGNC:HGNC:1052|Ensembl:ENSG00000136717|Vega:OTTHUMG00000131465 +275 AMT MIM:238310|HGNC:HGNC:473|Ensembl:ENSG00000145020|Vega:OTTHUMG00000156847 +276 AMY1A MIM:104700|HGNC:HGNC:474|Ensembl:ENSG00000237763|Vega:OTTHUMG00000011020 +277 AMY1B MIM:104701|HGNC:HGNC:475|Ensembl:ENSG00000174876|Vega:OTTHUMG00000011021 +278 AMY1C MIM:104702|HGNC:HGNC:476|Ensembl:ENSG00000187733|Vega:OTTHUMG00000011045 +279 AMY2A MIM:104650|HGNC:HGNC:477|Ensembl:ENSG00000243480|Vega:OTTHUMG00000011023 +280 AMY2B MIM:104660|HGNC:HGNC:478|Ensembl:ENSG00000240038|Vega:OTTHUMG00000011024 +281 AMYP1 HGNC:HGNC:479 +282 ANCR HGNC:HGNC:482 +283 ANG MIM:105850|HGNC:HGNC:483|Ensembl:ENSG00000214274|Vega:OTTHUMG00000029576 +284 ANGPT1 MIM:601667|HGNC:HGNC:484|Ensembl:ENSG00000154188|Vega:OTTHUMG00000164812 +285 ANGPT2 MIM:601922|HGNC:HGNC:485|Ensembl:ENSG00000091879|Vega:OTTHUMG00000090365 +286 ANK1 MIM:612641|HGNC:HGNC:492|Ensembl:ENSG00000029534|Vega:OTTHUMG00000150281 +287 ANK2 MIM:106410|HGNC:HGNC:493|Ensembl:ENSG00000145362|Vega:OTTHUMG00000132912 +288 ANK3 MIM:600465|HGNC:HGNC:494|Ensembl:ENSG00000151150|Vega:OTTHUMG00000018288 +289 ANOP1 MIM:301590|HGNC:HGNC:498 +290 ANPEP MIM:151530|HGNC:HGNC:500|Ensembl:ENSG00000166825|Vega:OTTHUMG00000149814 +291 SLC25A4 MIM:103220|HGNC:HGNC:10990|Ensembl:ENSG00000151729|Vega:OTTHUMG00000134299 +292 SLC25A5 MIM:300150|HGNC:HGNC:10991|Ensembl:ENSG00000005022|Vega:OTTHUMG00000022715 +293 SLC25A6 MIM:300151|MIM:403000|HGNC:HGNC:10992|Ensembl:ENSG00000169100|Vega:OTTHUMG00000021058 +301 ANXA1 MIM:151690|HGNC:HGNC:533|Ensembl:ENSG00000135046|Vega:OTTHUMG00000020016 +302 ANXA2 MIM:151740|HGNC:HGNC:537|Ensembl:ENSG00000182718|Vega:OTTHUMG00000132763 +303 ANXA2P1 HGNC:HGNC:538 +304 ANXA2P2 HGNC:HGNC:539 +305 ANXA2P3 HGNC:HGNC:540 +306 ANXA3 MIM:106490|HGNC:HGNC:541|Ensembl:ENSG00000138772|Vega:OTTHUMG00000130198 +307 ANXA4 MIM:106491|HGNC:HGNC:542|Ensembl:ENSG00000196975|Vega:OTTHUMG00000129649 +308 ANXA5 MIM:131230|HGNC:HGNC:543|Ensembl:ENSG00000164111|Vega:OTTHUMG00000133034 +309 ANXA6 MIM:114070|HGNC:HGNC:544|Ensembl:ENSG00000197043|Vega:OTTHUMG00000164179 +310 ANXA7 MIM:186360|HGNC:HGNC:545|Ensembl:ENSG00000138279|Vega:OTTHUMG00000018463 +311 ANXA11 MIM:602572|HGNC:HGNC:535|Ensembl:ENSG00000122359|Vega:OTTHUMG00000018604 +312 ANXA13 MIM:602573|HGNC:HGNC:536|Ensembl:ENSG00000104537|Vega:OTTHUMG00000164987 +313 AOAH MIM:102593|HGNC:HGNC:548|Ensembl:ENSG00000136250|Vega:OTTHUMG00000023566 +314 AOC2 MIM:602268|HGNC:HGNC:549|Ensembl:ENSG00000131480|Vega:OTTHUMG00000180655 +316 AOX1 MIM:602841|HGNC:HGNC:553|Ensembl:ENSG00000138356|Vega:OTTHUMG00000154536 +317 APAF1 MIM:602233|HGNC:HGNC:576|Ensembl:ENSG00000120868|Vega:OTTHUMG00000170214 +318 NUDT2 MIM:602852|HGNC:HGNC:8049|Ensembl:ENSG00000164978|Vega:OTTHUMG00000019817 +319 APOF MIM:107760|HGNC:HGNC:615|Ensembl:ENSG00000175336|Vega:OTTHUMG00000170715 +320 APBA1 MIM:602414|HGNC:HGNC:578|Ensembl:ENSG00000107282|Vega:OTTHUMG00000019984 +321 APBA2 MIM:602712|HGNC:HGNC:579|Ensembl:ENSG00000034053|Vega:OTTHUMG00000129255 +322 APBB1 MIM:602709|HGNC:HGNC:581|Ensembl:ENSG00000166313|Vega:OTTHUMG00000165454 +323 APBB2 MIM:602710|HGNC:HGNC:582|Ensembl:ENSG00000163697|Vega:OTTHUMG00000160416 +324 APC MIM:611731|HGNC:HGNC:583|Ensembl:ENSG00000134982|Vega:OTTHUMG00000128806 +325 APCS MIM:104770|HGNC:HGNC:584|Ensembl:ENSG00000132703|Vega:OTTHUMG00000022741 +326 AIRE MIM:607358|HGNC:HGNC:360|Ensembl:ENSG00000160224|Vega:OTTHUMG00000086921 +327 APEH MIM:102645|HGNC:HGNC:586|Ensembl:ENSG00000164062|Vega:OTTHUMG00000156882 +328 APEX1 MIM:107748|HGNC:HGNC:587|Ensembl:ENSG00000100823|Vega:OTTHUMG00000029544 +329 BIRC2 MIM:601712|HGNC:HGNC:590|Ensembl:ENSG00000110330|Vega:OTTHUMG00000167325 +330 BIRC3 MIM:601721|HGNC:HGNC:591|Ensembl:ENSG00000023445|Vega:OTTHUMG00000167324 +331 XIAP MIM:300079|HGNC:HGNC:592|Ensembl:ENSG00000101966|Vega:OTTHUMG00000022336 +332 BIRC5 MIM:603352|HGNC:HGNC:593|Ensembl:ENSG00000089685|Vega:OTTHUMG00000177505 +333 APLP1 MIM:104775|HGNC:HGNC:597|Ensembl:ENSG00000105290|Vega:OTTHUMG00000180692 +334 APLP2 MIM:104776|HGNC:HGNC:598|Ensembl:ENSG00000084234|Vega:OTTHUMG00000165767 +335 APOA1 MIM:107680|HGNC:HGNC:600|Ensembl:ENSG00000118137|Vega:OTTHUMG00000046112 +336 APOA2 MIM:107670|HGNC:HGNC:601|Ensembl:ENSG00000158874|Vega:OTTHUMG00000034346 +337 APOA4 MIM:107690|HGNC:HGNC:602|Ensembl:ENSG00000110244|Vega:OTTHUMG00000046110 +338 APOB MIM:107730|HGNC:HGNC:603|Ensembl:ENSG00000084674|Vega:OTTHUMG00000090785 +339 APOBEC1 MIM:600130|HGNC:HGNC:604|Ensembl:ENSG00000111701|Vega:OTTHUMG00000141288 +341 APOC1 MIM:107710|HGNC:HGNC:607|Ensembl:ENSG00000130208|Vega:OTTHUMG00000180844 +342 APOC1P1 HGNC:HGNC:608|Ensembl:ENSG00000214855 +343 AQP8 MIM:603750|HGNC:HGNC:642|Ensembl:ENSG00000103375|Vega:OTTHUMG00000097013 +344 APOC2 MIM:608083|HGNC:HGNC:609|Ensembl:ENSG00000234906|Vega:OTTHUMG00000180847 +345 APOC3 MIM:107720|HGNC:HGNC:610|Ensembl:ENSG00000110245|Vega:OTTHUMG00000046115 +346 APOC4 MIM:600745|HGNC:HGNC:611|Ensembl:ENSG00000224916|Ensembl:ENSG00000267467|Vega:OTTHUMG00000180845|Vega:OTTHUMG00000180846 +347 APOD MIM:107740|HGNC:HGNC:612|Ensembl:ENSG00000189058|Vega:OTTHUMG00000155854 +348 APOE MIM:107741|HGNC:HGNC:613|Ensembl:ENSG00000130203|Vega:OTTHUMG00000128901 +350 APOH MIM:138700|HGNC:HGNC:616|Ensembl:ENSG00000091583|Vega:OTTHUMG00000179530 +351 APP MIM:104760|HGNC:HGNC:620|Ensembl:ENSG00000142192|Vega:OTTHUMG00000078438 +353 APRT MIM:102600|HGNC:HGNC:626|Ensembl:ENSG00000198931|Vega:OTTHUMG00000175454 +354 KLK3 MIM:176820|HGNC:HGNC:6364|Ensembl:ENSG00000142515|Vega:OTTHUMG00000182867 +355 FAS MIM:134637|HGNC:HGNC:11920|Ensembl:ENSG00000026103|Vega:OTTHUMG00000018701 +356 FASLG MIM:134638|HGNC:HGNC:11936|Ensembl:ENSG00000117560|Vega:OTTHUMG00000034841 +357 SHROOM2 MIM:300103|HGNC:HGNC:630|Ensembl:ENSG00000146950|Vega:OTTHUMG00000021121 +358 AQP1 MIM:107776|HGNC:HGNC:633|Ensembl:ENSG00000240583|Vega:OTTHUMG00000023944 +359 AQP2 MIM:107777|HGNC:HGNC:634|Ensembl:ENSG00000167580|Vega:OTTHUMG00000169709 +360 AQP3 MIM:600170|HGNC:HGNC:636|Ensembl:ENSG00000165272|Vega:OTTHUMG00000019769 +361 AQP4 MIM:600308|HGNC:HGNC:637|Ensembl:ENSG00000171885|Vega:OTTHUMG00000131955 +362 AQP5 MIM:600442|HGNC:HGNC:638|Ensembl:ENSG00000161798|Vega:OTTHUMG00000169710 +363 AQP6 MIM:601383|HGNC:HGNC:639|Ensembl:ENSG00000086159|Vega:OTTHUMG00000133548 +364 AQP7 MIM:602974|HGNC:HGNC:640|Ensembl:ENSG00000165269|Vega:OTTHUMG00000019773 +366 AQP9 MIM:602914|HGNC:HGNC:643|Ensembl:ENSG00000103569|Vega:OTTHUMG00000132631 +367 AR MIM:313700|HGNC:HGNC:644|Ensembl:ENSG00000169083|Vega:OTTHUMG00000021740 +368 ABCC6 MIM:603234|HGNC:HGNC:57|Ensembl:ENSG00000091262|Vega:OTTHUMG00000129967 +369 ARAF MIM:311010|HGNC:HGNC:646|Ensembl:ENSG00000078061|Vega:OTTHUMG00000021446 +372 ARCN1 MIM:600820|HGNC:HGNC:649|Ensembl:ENSG00000095139|Vega:OTTHUMG00000166340 +373 TRIM23 MIM:601747|HGNC:HGNC:660|Ensembl:ENSG00000113595|Vega:OTTHUMG00000097802 +374 AREG MIM:104640|HGNC:HGNC:651|Ensembl:ENSG00000109321|Vega:OTTHUMG00000130006 +375 ARF1 MIM:103180|HGNC:HGNC:652|Ensembl:ENSG00000143761|Vega:OTTHUMG00000037595 +377 ARF3 MIM:103190|HGNC:HGNC:654|Ensembl:ENSG00000134287|Vega:OTTHUMG00000168080 +378 ARF4 MIM:601177|HGNC:HGNC:655|Ensembl:ENSG00000168374|Vega:OTTHUMG00000158601 +379 ARL4D MIM:600732|HGNC:HGNC:656|Ensembl:ENSG00000175906|Vega:OTTHUMG00000180881 +380 ARF4P1 HGNC:HGNC:657 +381 ARF5 MIM:103188|HGNC:HGNC:658|Ensembl:ENSG00000004059|Vega:OTTHUMG00000023246 +382 ARF6 MIM:600464|HGNC:HGNC:659|Ensembl:ENSG00000165527|Vega:OTTHUMG00000140296 +383 ARG1 MIM:608313|HGNC:HGNC:663|Ensembl:ENSG00000118520|Vega:OTTHUMG00000015566 +384 ARG2 MIM:107830|HGNC:HGNC:664|Ensembl:ENSG00000081181|Vega:OTTHUMG00000171807 +387 RHOA MIM:165390|HGNC:HGNC:667|Ensembl:ENSG00000067560|Vega:OTTHUMG00000156838 +388 RHOB MIM:165370|HGNC:HGNC:668|Ensembl:ENSG00000143878|Vega:OTTHUMG00000090755 +389 RHOC MIM:165380|HGNC:HGNC:669|Ensembl:ENSG00000155366|Vega:OTTHUMG00000011905 +390 RND3 MIM:602924|HGNC:HGNC:671|Ensembl:ENSG00000115963|Vega:OTTHUMG00000131859 +391 RHOG MIM:179505|HGNC:HGNC:672|Ensembl:ENSG00000177105|Vega:OTTHUMG00000012287 +392 ARHGAP1 MIM:602732|HGNC:HGNC:673|Ensembl:ENSG00000175220|Vega:OTTHUMG00000166567 +393 ARHGAP4 MIM:300023|HGNC:HGNC:674|Ensembl:ENSG00000089820|Vega:OTTHUMG00000024226 +394 ARHGAP5 MIM:602680|HGNC:HGNC:675|Ensembl:ENSG00000100852|Vega:OTTHUMG00000170589 +395 ARHGAP6 MIM:300118|HGNC:HGNC:676|Ensembl:ENSG00000047648|Vega:OTTHUMG00000021134 +396 ARHGDIA MIM:601925|HGNC:HGNC:678|Ensembl:ENSG00000141522|Vega:OTTHUMG00000178352 +397 ARHGDIB MIM:602843|HGNC:HGNC:679|Ensembl:ENSG00000111348|Vega:OTTHUMG00000168742 +398 ARHGDIG MIM:602844|HGNC:HGNC:680|Ensembl:ENSG00000242173|Vega:OTTHUMG00000064892 +399 RHOH MIM:602037|HGNC:HGNC:686|Ensembl:ENSG00000168421|Vega:OTTHUMG00000099373 +400 ARL1 MIM:603425|HGNC:HGNC:692|Ensembl:ENSG00000120805|Vega:OTTHUMG00000170271 +401 PHOX2A MIM:602753|HGNC:HGNC:691|Ensembl:ENSG00000165462|Vega:OTTHUMG00000167899 +402 ARL2 MIM:601175|HGNC:HGNC:693|Ensembl:ENSG00000213465|Vega:OTTHUMG00000165728 +403 ARL3 MIM:604695|HGNC:HGNC:694|Ensembl:ENSG00000138175|Vega:OTTHUMG00000018965 +405 ARNT MIM:126110|HGNC:HGNC:700|Ensembl:ENSG00000143437|Vega:OTTHUMG00000035011 +406 ARNTL MIM:602550|HGNC:HGNC:701|Ensembl:ENSG00000133794|Vega:OTTHUMG00000150623 +407 ARR3 MIM:301770|HGNC:HGNC:710|Ensembl:ENSG00000120500|Vega:OTTHUMG00000021768 +408 ARRB1 MIM:107940|HGNC:HGNC:711|Ensembl:ENSG00000137486|Vega:OTTHUMG00000165444 +409 ARRB2 MIM:107941|HGNC:HGNC:712|Ensembl:ENSG00000141480|Vega:OTTHUMG00000090759 +410 ARSA MIM:607574|HGNC:HGNC:713|Ensembl:ENSG00000100299|Vega:OTTHUMG00000150180 +411 ARSB MIM:611542|HGNC:HGNC:714|Ensembl:ENSG00000113273|Vega:OTTHUMG00000108129 +412 STS MIM:300747|HGNC:HGNC:11425|Ensembl:ENSG00000101846|Vega:OTTHUMG00000021102 +413 ARSC2 MIM:301780|HGNC:HGNC:716 +414 ARSD MIM:300002|HGNC:HGNC:717|Ensembl:ENSG00000006756|Vega:OTTHUMG00000021077 +415 ARSE MIM:300180|HGNC:HGNC:719|Ensembl:ENSG00000157399|Vega:OTTHUMG00000137358 +416 ARSF MIM:300003|HGNC:HGNC:721|Ensembl:ENSG00000062096|Vega:OTTHUMG00000021081 +417 ART1 MIM:601625|HGNC:HGNC:723|Ensembl:ENSG00000129744|Vega:OTTHUMG00000011845 +418 ART2P HGNC:HGNC:724 +419 ART3 MIM:603086|HGNC:HGNC:725|Ensembl:ENSG00000156219|Vega:OTTHUMG00000130110 +420 ART4 MIM:110600|HGNC:HGNC:726|Ensembl:ENSG00000111339|Vega:OTTHUMG00000168738 +421 ARVCF MIM:602269|HGNC:HGNC:728|Ensembl:ENSG00000099889|Vega:OTTHUMG00000030426 +424 ARVD3 MIM:602086|HGNC:HGNC:731 +425 ARVD4 MIM:602087|HGNC:HGNC:732 +427 ASAH1 MIM:613468|HGNC:HGNC:735|Ensembl:ENSG00000104763|Vega:OTTHUMG00000096997 +429 ASCL1 MIM:100790|HGNC:HGNC:738|Ensembl:ENSG00000139352|Vega:OTTHUMG00000169967 +430 ASCL2 MIM:601886|HGNC:HGNC:739|Ensembl:ENSG00000183734|Vega:OTTHUMG00000009648 +431 ASD1 MIM:108800|HGNC:HGNC:741 +432 ASGR1 MIM:108360|HGNC:HGNC:742|Ensembl:ENSG00000141505|Vega:OTTHUMG00000102159 +433 ASGR2 MIM:108361|HGNC:HGNC:743|Ensembl:ENSG00000161944|Vega:OTTHUMG00000102158 +434 ASIP MIM:600201|HGNC:HGNC:745|Ensembl:ENSG00000101440|Vega:OTTHUMG00000032289 +435 ASL MIM:608310|HGNC:HGNC:746|Ensembl:ENSG00000126522|Vega:OTTHUMG00000022876 +436 ASLP1 HGNC:HGNC:747 +438 ASMT MIM:300015|MIM:402500|HGNC:HGNC:750|Ensembl:ENSG00000196433|Vega:OTTHUMG00000021065 +439 ASNA1 MIM:601913|HGNC:HGNC:752|Ensembl:ENSG00000198356|Vega:OTTHUMG00000180355 +440 ASNS MIM:108370|HGNC:HGNC:753|Ensembl:ENSG00000070669|Vega:OTTHUMG00000022892 +442 ASNSP2 HGNC:HGNC:755 +443 ASPA MIM:608034|HGNC:HGNC:756|Ensembl:ENSG00000108381|Vega:OTTHUMG00000090655 +444 ASPH MIM:600582|HGNC:HGNC:757|Ensembl:ENSG00000198363|Vega:OTTHUMG00000164375 +445 ASS1 MIM:603470|HGNC:HGNC:758|Ensembl:ENSG00000130707|Vega:OTTHUMG00000020806 +447 ASS1P2 HGNC:HGNC:765 +449 ASS1P4 HGNC:HGNC:767 +450 ASS1P5 HGNC:HGNC:768 +451 ASS1P6 HGNC:HGNC:769 +453 ASS1P8 HGNC:HGNC:771 +454 ASS1P9 HGNC:HGNC:772 +455 ASS1P10 HGNC:HGNC:760 +459 ASS1P14 HGNC:HGNC:764 +460 ASTN1 MIM:600904|HGNC:HGNC:773|Ensembl:ENSG00000152092|Vega:OTTHUMG00000035041 +462 SERPINC1 MIM:107300|HGNC:HGNC:775|Ensembl:ENSG00000117601|Vega:OTTHUMG00000037276 +463 ZFHX3 MIM:104155|HGNC:HGNC:777|Ensembl:ENSG00000140836|Vega:OTTHUMG00000137599 +465 ATD MIM:208500|HGNC:HGNC:780 +466 ATF1 MIM:123803|HGNC:HGNC:783|Ensembl:ENSG00000123268|Vega:OTTHUMG00000169482 +467 ATF3 MIM:603148|HGNC:HGNC:785|Ensembl:ENSG00000162772|Vega:OTTHUMG00000036747 +468 ATF4 MIM:604064|HGNC:HGNC:786|Ensembl:ENSG00000128272|Vega:OTTHUMG00000151099 +469 ATF4P1 HGNC:HGNC:789 +470 ATHS MIM:108725|HGNC:HGNC:793 +471 ATIC MIM:601731|HGNC:HGNC:794|Ensembl:ENSG00000138363|Vega:OTTHUMG00000133023 +472 ATM MIM:607585|HGNC:HGNC:795|Ensembl:ENSG00000149311|Vega:OTTHUMG00000166480 +473 RERE MIM:605226|HGNC:HGNC:9965|Ensembl:ENSG00000142599|Vega:OTTHUMG00000001765 +474 ATOH1 MIM:601461|HGNC:HGNC:797|Ensembl:ENSG00000172238|Vega:OTTHUMG00000130972 +475 ATOX1 MIM:602270|HGNC:HGNC:798|Ensembl:ENSG00000177556|Vega:OTTHUMG00000163499 +476 ATP1A1 MIM:182310|HGNC:HGNC:799|Ensembl:ENSG00000163399|Vega:OTTHUMG00000012109 +477 ATP1A2 MIM:182340|HGNC:HGNC:800|Ensembl:ENSG00000018625|Vega:OTTHUMG00000024080 +478 ATP1A3 MIM:182350|HGNC:HGNC:801|Ensembl:ENSG00000105409|Vega:OTTHUMG00000137384 +479 ATP12A MIM:182360|HGNC:HGNC:13816|Ensembl:ENSG00000075673|Vega:OTTHUMG00000016588 +480 ATP1A4 MIM:607321|HGNC:HGNC:14073|Ensembl:ENSG00000132681|Vega:OTTHUMG00000031609 +481 ATP1B1 MIM:182330|HGNC:HGNC:804|Ensembl:ENSG00000143153|Vega:OTTHUMG00000034590 +482 ATP1B2 MIM:182331|HGNC:HGNC:805|Ensembl:ENSG00000129244|Vega:OTTHUMG00000178018 +483 ATP1B3 MIM:601867|HGNC:HGNC:806|Ensembl:ENSG00000069849|Vega:OTTHUMG00000159081 +484 ATP1B3P1 HGNC:HGNC:807 +485 ATP1B1P1 HGNC:HGNC:809 +486 FXYD2 MIM:601814|HGNC:HGNC:4026|Ensembl:ENSG00000137731|Vega:OTTHUMG00000166990 +487 ATP2A1 MIM:108730|HGNC:HGNC:811|Ensembl:ENSG00000196296|Vega:OTTHUMG00000131760 +488 ATP2A2 MIM:108740|HGNC:HGNC:812|Ensembl:ENSG00000174437|Vega:OTTHUMG00000169327 +489 ATP2A3 MIM:601929|HGNC:HGNC:813|Ensembl:ENSG00000074370|Vega:OTTHUMG00000177674 +490 ATP2B1 MIM:108731|HGNC:HGNC:814|Ensembl:ENSG00000070961|Vega:OTTHUMG00000169946 +491 ATP2B2 MIM:108733|HGNC:HGNC:815|Ensembl:ENSG00000157087|Vega:OTTHUMG00000128679 +492 ATP2B3 MIM:300014|HGNC:HGNC:816|Ensembl:ENSG00000067842|Vega:OTTHUMG00000024202 +493 ATP2B4 MIM:108732|HGNC:HGNC:817|Ensembl:ENSG00000058668|Vega:OTTHUMG00000035906 +495 ATP4A MIM:137216|HGNC:HGNC:819|Ensembl:ENSG00000105675|Vega:OTTHUMG00000048106 +496 ATP4B MIM:137217|HGNC:HGNC:820|Ensembl:ENSG00000186009|Vega:OTTHUMG00000140234 +498 ATP5A1 MIM:164360|HGNC:HGNC:823|Ensembl:ENSG00000152234|Vega:OTTHUMG00000132637 +501 ALDH7A1 MIM:107323|HGNC:HGNC:877|Ensembl:ENSG00000164904|Vega:OTTHUMG00000128942 +504 ATP5A1P2 HGNC:HGNC:828 +506 ATP5B MIM:102910|HGNC:HGNC:830|Ensembl:ENSG00000110955 +507 ATP5BP1 HGNC:HGNC:831 +509 ATP5C1 MIM:108729|HGNC:HGNC:833|Ensembl:ENSG00000165629|Vega:OTTHUMG00000017639 +513 ATP5D MIM:603150|HGNC:HGNC:837|Ensembl:ENSG00000099624|Vega:OTTHUMG00000180143 +514 ATP5E MIM:606153|HGNC:HGNC:838|Ensembl:ENSG00000124172|Vega:OTTHUMG00000032854 +515 ATP5F1 MIM:603270|HGNC:HGNC:840|Ensembl:ENSG00000116459|Vega:OTTHUMG00000011745 +516 ATP5G1 MIM:603192|HGNC:HGNC:841|Ensembl:ENSG00000159199|Vega:OTTHUMG00000160520 +517 ATP5G2 MIM:603193|HGNC:HGNC:842|Ensembl:ENSG00000135390|Vega:OTTHUMG00000133442 +518 ATP5G3 MIM:602736|HGNC:HGNC:843|Ensembl:ENSG00000154518|Vega:OTTHUMG00000132425 +520 ATP5G2P1 HGNC:HGNC:844 +521 ATP5I MIM:601519|HGNC:HGNC:846|Ensembl:ENSG00000169020|Vega:OTTHUMG00000086929 +522 ATP5J MIM:603152|HGNC:HGNC:847|Ensembl:ENSG00000154723|Vega:OTTHUMG00000078442 +523 ATP6V1A MIM:607027|HGNC:HGNC:851|Ensembl:ENSG00000114573|Vega:OTTHUMG00000159295 +525 ATP6V1B1 MIM:192132|HGNC:HGNC:853|Ensembl:ENSG00000116039|Vega:OTTHUMG00000129711 +526 ATP6V1B2 MIM:606939|HGNC:HGNC:854|Ensembl:ENSG00000147416|Vega:OTTHUMG00000131073 +527 ATP6V0C MIM:108745|HGNC:HGNC:855|Ensembl:ENSG00000185883|Vega:OTTHUMG00000128865 +528 ATP6V1C1 MIM:603097|HGNC:HGNC:856|Ensembl:ENSG00000155097|Vega:OTTHUMG00000164761 +529 ATP6V1E1 MIM:108746|HGNC:HGNC:857|Ensembl:ENSG00000131100|Vega:OTTHUMG00000059320 +533 ATP6V0B MIM:603717|HGNC:HGNC:861|Ensembl:ENSG00000117410|Vega:OTTHUMG00000008298 +534 ATP6V1G2 MIM:606853|HGNC:HGNC:862|Ensembl:ENSG00000213760|Vega:OTTHUMG00000166618 +535 ATP6V0A1 MIM:192130|HGNC:HGNC:865|Ensembl:ENSG00000033627|Vega:OTTHUMG00000180238 +537 ATP6AP1 MIM:300197|HGNC:HGNC:868|Ensembl:ENSG00000071553|Vega:OTTHUMG00000033291 +538 ATP7A MIM:300011|HGNC:HGNC:869|Ensembl:ENSG00000165240|Vega:OTTHUMG00000021885 +539 ATP5O MIM:600828|HGNC:HGNC:850|Ensembl:ENSG00000241837|Vega:OTTHUMG00000065186 +540 ATP7B MIM:606882|HGNC:HGNC:870|Ensembl:ENSG00000123191|Vega:OTTHUMG00000017406 +541 ALDH7A1P1 HGNC:HGNC:878 +542 ALDH7A1P2 HGNC:HGNC:879 +543 ALDH7A1P3 HGNC:HGNC:880 +544 ALDH7A1P4 HGNC:HGNC:881 +545 ATR MIM:601215|HGNC:HGNC:882|Ensembl:ENSG00000175054|Vega:OTTHUMG00000159234 +546 ATRX MIM:300032|MIM:300504|HGNC:HGNC:886|Ensembl:ENSG00000085224|Vega:OTTHUMG00000022686 +547 KIF1A MIM:601255|HGNC:HGNC:888|Ensembl:ENSG00000130294|Vega:OTTHUMG00000151940 +549 AUH MIM:600529|HGNC:HGNC:890|Ensembl:ENSG00000148090|Vega:OTTHUMG00000020207 +550 AUP1 MIM:602434|HGNC:HGNC:891|Ensembl:ENSG00000115307|Vega:OTTHUMG00000129964 +551 AVP MIM:192340|HGNC:HGNC:894|Ensembl:ENSG00000101200|Vega:OTTHUMG00000031733 +552 AVPR1A MIM:600821|HGNC:HGNC:895|Ensembl:ENSG00000166148|Vega:OTTHUMG00000169980 +553 AVPR1B MIM:600264|HGNC:HGNC:896|Ensembl:ENSG00000198049|Vega:OTTHUMG00000184377 +554 AVPR2 MIM:300538|HGNC:HGNC:897|Ensembl:ENSG00000126895|Vega:OTTHUMG00000024227 +558 AXL MIM:109135|HGNC:HGNC:905|Ensembl:ENSG00000167601|Vega:OTTHUMG00000182727 +560 AZF1 MIM:415000|HGNC:HGNC:908 +563 AZGP1 MIM:194460|HGNC:HGNC:910|Ensembl:ENSG00000160862|Vega:OTTHUMG00000023066 +566 AZU1 MIM:162815|HGNC:HGNC:913|Ensembl:ENSG00000172232|Vega:OTTHUMG00000187023 +567 B2M MIM:109700|HGNC:HGNC:914|Ensembl:ENSG00000166710|Vega:OTTHUMG00000131247 +568 B2MR MIM:109710|HGNC:HGNC:915 +570 BAAT MIM:602938|HGNC:HGNC:932|Ensembl:ENSG00000136881|Vega:OTTHUMG00000020377 +571 BACH1 MIM:602751|HGNC:HGNC:935|Ensembl:ENSG00000156273|Vega:OTTHUMG00000078878 +572 BAD MIM:603167|HGNC:HGNC:936|Ensembl:ENSG00000002330|Vega:OTTHUMG00000134302 +573 BAG1 MIM:601497|HGNC:HGNC:937|Ensembl:ENSG00000107262|Vega:OTTHUMG00000019766 +574 BAGE MIM:605167|HGNC:HGNC:942 +575 ADGRB1 MIM:602682|HGNC:HGNC:943|Ensembl:ENSG00000181790|Vega:OTTHUMG00000164732 +576 ADGRB2 MIM:602683|HGNC:HGNC:944|Ensembl:ENSG00000121753|Vega:OTTHUMG00000003885 +577 ADGRB3 MIM:602684|HGNC:HGNC:945|Ensembl:ENSG00000135298|Vega:OTTHUMG00000014982 +578 BAK1 MIM:600516|HGNC:HGNC:949|Ensembl:ENSG00000030110|Vega:OTTHUMG00000014530 +579 NKX3-2 MIM:602183|HGNC:HGNC:951|Ensembl:ENSG00000109705|Vega:OTTHUMG00000090657 +580 BARD1 MIM:601593|HGNC:HGNC:952|Ensembl:ENSG00000138376|Vega:OTTHUMG00000133016 +581 BAX MIM:600040|HGNC:HGNC:959|Ensembl:ENSG00000087088|Vega:OTTHUMG00000160476 +582 BBS1 MIM:209901|HGNC:HGNC:966|Ensembl:ENSG00000174483|Ensembl:ENSG00000256349|Vega:OTTHUMG00000167110|Vega:OTTHUMG00000167719 +583 BBS2 MIM:606151|HGNC:HGNC:967|Ensembl:ENSG00000125124|Vega:OTTHUMG00000176943 +585 BBS4 MIM:600374|HGNC:HGNC:969|Ensembl:ENSG00000140463|Vega:OTTHUMG00000133510 +586 BCAT1 MIM:113520|HGNC:HGNC:976|Ensembl:ENSG00000060982|Vega:OTTHUMG00000169053 +587 BCAT2 MIM:113530|HGNC:HGNC:977|Ensembl:ENSG00000105552|Vega:OTTHUMG00000183327 +590 BCHE MIM:177400|HGNC:HGNC:983|Ensembl:ENSG00000114200|Vega:OTTHUMG00000158131 +593 BCKDHA MIM:608348|HGNC:HGNC:986|Ensembl:ENSG00000248098|Vega:OTTHUMG00000168128 +594 BCKDHB MIM:248611|HGNC:HGNC:987|Ensembl:ENSG00000083123|Vega:OTTHUMG00000016430 +595 CCND1 MIM:168461|HGNC:HGNC:1582|Ensembl:ENSG00000110092|Vega:OTTHUMG00000167877 +596 BCL2 MIM:151430|HGNC:HGNC:990|Ensembl:ENSG00000171791|Vega:OTTHUMG00000132791 +597 BCL2A1 MIM:601056|HGNC:HGNC:991|Ensembl:ENSG00000140379|Vega:OTTHUMG00000144173 +598 BCL2L1 MIM:600039|HGNC:HGNC:992|Ensembl:ENSG00000171552|Vega:OTTHUMG00000032192 +599 BCL2L2 MIM:601931|HGNC:HGNC:995|Ensembl:ENSG00000129473|Vega:OTTHUMG00000028738 +600 BAK1P1 HGNC:HGNC:996 +601 BAK1P2 HGNC:HGNC:997 +602 BCL3 MIM:109560|HGNC:HGNC:998|Ensembl:ENSG00000069399|Vega:OTTHUMG00000151517 +603 BCL5 MIM:151441|HGNC:HGNC:1000 +604 BCL6 MIM:109565|HGNC:HGNC:1001|Ensembl:ENSG00000113916|Vega:OTTHUMG00000156441 +605 BCL7A MIM:601406|HGNC:HGNC:1004|Ensembl:ENSG00000110987|Vega:OTTHUMG00000168951 +606 NBEAP1 MIM:601889|HGNC:HGNC:1007 +607 BCL9 MIM:602597|HGNC:HGNC:1008|Ensembl:ENSG00000116128|Vega:OTTHUMG00000014031 +608 TNFRSF17 MIM:109545|HGNC:HGNC:11913|Ensembl:ENSG00000048462|Vega:OTTHUMG00000129826 +610 HCN2 MIM:602781|HGNC:HGNC:4846|Ensembl:ENSG00000099822|Vega:OTTHUMG00000180590 +611 OPN1SW MIM:613522|HGNC:HGNC:1012|Ensembl:ENSG00000128617|Vega:OTTHUMG00000158311 +613 BCR MIM:151410|HGNC:HGNC:1014|Ensembl:ENSG00000186716|Vega:OTTHUMG00000150655 +616 BCRP4 HGNC:HGNC:1017 +617 BCS1L MIM:603647|HGNC:HGNC:1020|Ensembl:ENSG00000074582|Vega:OTTHUMG00000133114 +618 BCYRN1 MIM:606089|HGNC:HGNC:1022|Ensembl:ENSG00000236824 +619 BCYRN1P1 HGNC:HGNC:1023 +620 BCYRN1P2 HGNC:HGNC:1024 +622 BDH1 MIM:603063|HGNC:HGNC:1027|Ensembl:ENSG00000161267|Vega:OTTHUMG00000155478 +623 BDKRB1 MIM:600337|HGNC:HGNC:1029|Ensembl:ENSG00000100739|Vega:OTTHUMG00000171412 +624 BDKRB2 MIM:113503|HGNC:HGNC:1030|Ensembl:ENSG00000168398|Vega:OTTHUMG00000171408 +627 BDNF MIM:113505|HGNC:HGNC:1033|Ensembl:ENSG00000176697|Vega:OTTHUMG00000178797 +628 BEVI MIM:109180 +629 CFB MIM:138470|HGNC:HGNC:1037|Ensembl:ENSG00000243649|Vega:OTTHUMG00000031198 +631 BFSP1 MIM:603307|HGNC:HGNC:1040|Ensembl:ENSG00000125864|Vega:OTTHUMG00000031940 +632 BGLAP MIM:112260|HGNC:HGNC:1043|Ensembl:ENSG00000242252|Vega:OTTHUMG00000014819 +633 BGN MIM:301870|HGNC:HGNC:1044|Ensembl:ENSG00000182492|Vega:OTTHUMG00000024205 +634 CEACAM1 MIM:109770|HGNC:HGNC:1814|Ensembl:ENSG00000079385|Vega:OTTHUMG00000151078 +635 BHMT MIM:602888|HGNC:HGNC:1047|Ensembl:ENSG00000145692|Vega:OTTHUMG00000108157 +636 BICD1 MIM:602204|HGNC:HGNC:1049|Ensembl:ENSG00000151746|Vega:OTTHUMG00000169307 +637 BID MIM:601997|HGNC:HGNC:1050|Ensembl:ENSG00000015475|Vega:OTTHUMG00000150087 +638 BIK MIM:603392|HGNC:HGNC:1051|Ensembl:ENSG00000100290|Vega:OTTHUMG00000150703 +639 PRDM1 MIM:603423|HGNC:HGNC:9346|Ensembl:ENSG00000057657|Vega:OTTHUMG00000015299 +640 BLK MIM:191305|HGNC:HGNC:1057|Ensembl:ENSG00000136573|Vega:OTTHUMG00000090729 +641 BLM MIM:604610|HGNC:HGNC:1058|Ensembl:ENSG00000197299|Vega:OTTHUMG00000149834 +642 BLMH MIM:602403|HGNC:HGNC:1059|Ensembl:ENSG00000108578|Vega:OTTHUMG00000179756 +643 CXCR5 MIM:601613|HGNC:HGNC:1060|Ensembl:ENSG00000160683|Vega:OTTHUMG00000166345 +644 BLVRA MIM:109750|HGNC:HGNC:1062|Ensembl:ENSG00000106605|Vega:OTTHUMG00000128953 +645 BLVRB MIM:600941|HGNC:HGNC:1063|Ensembl:ENSG00000090013|Vega:OTTHUMG00000182593 +646 BNC1 MIM:601930|HGNC:HGNC:1081|Ensembl:ENSG00000169594|Vega:OTTHUMG00000147362 +648 BMI1 MIM:164831|HGNC:HGNC:1066|Ensembl:ENSG00000168283|Vega:OTTHUMG00000017807 +649 BMP1 MIM:112264|HGNC:HGNC:1067|Ensembl:ENSG00000168487|Vega:OTTHUMG00000097761 +650 BMP2 MIM:112261|HGNC:HGNC:1069|Ensembl:ENSG00000125845|Vega:OTTHUMG00000031833 +651 BMP3 MIM:112263|HGNC:HGNC:1070|Ensembl:ENSG00000152785|Vega:OTTHUMG00000130292 +652 BMP4 MIM:112262|HGNC:HGNC:1071|Ensembl:ENSG00000125378|Vega:OTTHUMG00000140303 +653 BMP5 MIM:112265|HGNC:HGNC:1072|Ensembl:ENSG00000112175|Vega:OTTHUMG00000014903 +654 BMP6 MIM:112266|HGNC:HGNC:1073|Ensembl:ENSG00000153162|Vega:OTTHUMG00000014217 +655 BMP7 MIM:112267|HGNC:HGNC:1074|Ensembl:ENSG00000101144|Vega:OTTHUMG00000032812 +656 BMP8B MIM:602284|HGNC:HGNC:1075|Ensembl:ENSG00000116985|Vega:OTTHUMG00000009247 +657 BMPR1A MIM:601299|HGNC:HGNC:1076|Ensembl:ENSG00000107779|Vega:OTTHUMG00000018657 +658 BMPR1B MIM:603248|HGNC:HGNC:1077|Ensembl:ENSG00000138696|Vega:OTTHUMG00000130991 +659 BMPR2 MIM:600799|HGNC:HGNC:1078|Ensembl:ENSG00000204217|Vega:OTTHUMG00000133617 +660 BMX MIM:300101|HGNC:HGNC:1079|Ensembl:ENSG00000102010|Vega:OTTHUMG00000021180 +661 POLR3D MIM:187280|HGNC:HGNC:1080|Ensembl:ENSG00000168495|Vega:OTTHUMG00000163778 +662 BNIP1 MIM:603291|HGNC:HGNC:1082|Ensembl:ENSG00000113734|Vega:OTTHUMG00000130521 +663 BNIP2 MIM:603292|HGNC:HGNC:1083|Ensembl:ENSG00000140299|Vega:OTTHUMG00000132727 +664 BNIP3 MIM:603293|HGNC:HGNC:1084|Ensembl:ENSG00000176171|Vega:OTTHUMG00000019278 +665 BNIP3L MIM:605368|HGNC:HGNC:1085|Ensembl:ENSG00000104765|Vega:OTTHUMG00000099433 +666 BOK MIM:605404|HGNC:HGNC:1087|Ensembl:ENSG00000176720|Vega:OTTHUMG00000133411 +667 DST MIM:113810|HGNC:HGNC:1090|Ensembl:ENSG00000151914|Vega:OTTHUMG00000014913 +668 FOXL2 MIM:605597|HGNC:HGNC:1092|Ensembl:ENSG00000183770|Vega:OTTHUMG00000159889 +669 BPGM MIM:613896|HGNC:HGNC:1093|Ensembl:ENSG00000172331|Vega:OTTHUMG00000155380 +670 BPHL MIM:603156|HGNC:HGNC:1094|Ensembl:ENSG00000137274|Vega:OTTHUMG00000014140 +671 BPI MIM:109195|HGNC:HGNC:1095|Ensembl:ENSG00000101425|Vega:OTTHUMG00000032441 +672 BRCA1 MIM:113705|HGNC:HGNC:1100|Ensembl:ENSG00000012048|Vega:OTTHUMG00000157426 +673 BRAF MIM:164757|HGNC:HGNC:1097|Ensembl:ENSG00000157764|Vega:OTTHUMG00000157457 +675 BRCA2 MIM:600185|HGNC:HGNC:1101|Ensembl:ENSG00000139618|Vega:OTTHUMG00000017411 +676 BRDT MIM:602144|HGNC:HGNC:1105|Ensembl:ENSG00000137948|Vega:OTTHUMG00000010113 +677 ZFP36L1 MIM:601064|HGNC:HGNC:1107|Ensembl:ENSG00000185650|Vega:OTTHUMG00000171385 +678 ZFP36L2 MIM:612053|HGNC:HGNC:1108|Ensembl:ENSG00000152518|Vega:OTTHUMG00000128642 +680 BRS3 MIM:300107|HGNC:HGNC:1113|Ensembl:ENSG00000102239|Vega:OTTHUMG00000022726 +682 BSG MIM:109480|HGNC:HGNC:1116|Ensembl:ENSG00000172270|Vega:OTTHUMG00000177718 +683 BST1 MIM:600387|HGNC:HGNC:1118|Ensembl:ENSG00000109743|Vega:OTTHUMG00000097739 +684 BST2 MIM:600534|HGNC:HGNC:1119|Ensembl:ENSG00000130303|Vega:OTTHUMG00000191770 +685 BTC MIM:600345|HGNC:HGNC:1121|Ensembl:ENSG00000174808|Vega:OTTHUMG00000130107 +686 BTD MIM:609019|HGNC:HGNC:1122|Ensembl:ENSG00000169814|Vega:OTTHUMG00000129861 +687 KLF9 MIM:602902|HGNC:HGNC:1123|Ensembl:ENSG00000119138|Vega:OTTHUMG00000019991 +688 KLF5 MIM:602903|HGNC:HGNC:6349|Ensembl:ENSG00000102554|Vega:OTTHUMG00000017074 +689 BTF3 MIM:602542|HGNC:HGNC:1125|Ensembl:ENSG00000145741|Vega:OTTHUMG00000102031 +690 BTF3P11 MIM:602543|HGNC:HGNC:1126 +693 BTF3P1 HGNC:HGNC:1129 +694 BTG1 MIM:109580|HGNC:HGNC:1130|Ensembl:ENSG00000133639|Vega:OTTHUMG00000170092 +695 BTK MIM:300300|HGNC:HGNC:1133|Ensembl:ENSG00000010671|Vega:OTTHUMG00000022022 +696 BTN1A1 MIM:601610|HGNC:HGNC:1135|Ensembl:ENSG00000124557|Vega:OTTHUMG00000016358 +698 BTS1 HGNC:HGNC:1147 +699 BUB1 MIM:602452|HGNC:HGNC:1148|Ensembl:ENSG00000169679|Vega:OTTHUMG00000153638 +700 BVR1 HGNC:HGNC:1153 +701 BUB1B MIM:602860|HGNC:HGNC:1149|Ensembl:ENSG00000156970|Vega:OTTHUMG00000129877 +705 BYSL MIM:603871|HGNC:HGNC:1157|Ensembl:ENSG00000112578|Vega:OTTHUMG00000014687 +706 TSPO MIM:109610|HGNC:HGNC:1158|Ensembl:ENSG00000100300|Vega:OTTHUMG00000150573 +708 C1QBP MIM:601269|HGNC:HGNC:1243|Ensembl:ENSG00000108561|Vega:OTTHUMG00000177875 +710 SERPING1 MIM:606860|HGNC:HGNC:1228|Ensembl:ENSG00000149131|Vega:OTTHUMG00000150304 +711 ERC2-IT1 HGNC:HGNC:1229|Ensembl:ENSG00000281708 +712 C1QA MIM:120550|HGNC:HGNC:1241|Ensembl:ENSG00000173372|Vega:OTTHUMG00000002893 +713 C1QB MIM:120570|HGNC:HGNC:1242|Ensembl:ENSG00000173369|Vega:OTTHUMG00000002896 +714 C1QC MIM:120575|HGNC:HGNC:1245|Ensembl:ENSG00000159189|Vega:OTTHUMG00000002891 +715 C1R MIM:613785|HGNC:HGNC:1246|Ensembl:ENSG00000159403|Vega:OTTHUMG00000168149 +716 C1S MIM:120580|HGNC:HGNC:1247|Ensembl:ENSG00000182326|Vega:OTTHUMG00000150305 +717 C2 MIM:613927|HGNC:HGNC:1248|Ensembl:ENSG00000166278|Vega:OTTHUMG00000031190 +718 C3 MIM:120700|HGNC:HGNC:1318|Ensembl:ENSG00000125730|Vega:OTTHUMG00000150335 +719 C3AR1 MIM:605246|HGNC:HGNC:1319|Ensembl:ENSG00000171860|Vega:OTTHUMG00000168569 +720 C4A MIM:120810|HGNC:HGNC:1323|Ensembl:ENSG00000244731|Vega:OTTHUMG00000031186 +721 C4B MIM:120820|HGNC:HGNC:1324|Ensembl:ENSG00000224389|Vega:OTTHUMG00000031187 +722 C4BPA MIM:120830|HGNC:HGNC:1325|Ensembl:ENSG00000123838|Vega:OTTHUMG00000036173 +724 C4BPAP2 HGNC:HGNC:1327 +725 C4BPB MIM:120831|HGNC:HGNC:1328|Ensembl:ENSG00000123843|Vega:OTTHUMG00000036035 +726 CAPN5 MIM:602537|HGNC:HGNC:1482|Ensembl:ENSG00000149260|Vega:OTTHUMG00000165192 +727 C5 MIM:120900|HGNC:HGNC:1331|Ensembl:ENSG00000106804|Vega:OTTHUMG00000020579 +728 C5AR1 MIM:113995|HGNC:HGNC:1338|Ensembl:ENSG00000197405|Vega:OTTHUMG00000183504 +729 C6 MIM:217050|HGNC:HGNC:1339|Ensembl:ENSG00000039537|Vega:OTTHUMG00000094781 +730 C7 MIM:217070|HGNC:HGNC:1346|Ensembl:ENSG00000112936|Vega:OTTHUMG00000150340 +731 C8A MIM:120950|HGNC:HGNC:1352|Ensembl:ENSG00000157131|Vega:OTTHUMG00000008306 +732 C8B MIM:120960|HGNC:HGNC:1353|Ensembl:ENSG00000021852|Vega:OTTHUMG00000008305 +733 C8G MIM:120930|HGNC:HGNC:1354|Ensembl:ENSG00000176919|Vega:OTTHUMG00000020955 +734 OSGIN2 MIM:604598|HGNC:HGNC:1355|Ensembl:ENSG00000164823|Vega:OTTHUMG00000163811 +735 C9 MIM:120940|HGNC:HGNC:1358|Ensembl:ENSG00000113600|Vega:OTTHUMG00000094767 +738 VPS51 MIM:615738|HGNC:HGNC:1172|Ensembl:ENSG00000149823|Vega:OTTHUMG00000165600 +740 MRPL49 MIM:606866|HGNC:HGNC:1176|Ensembl:ENSG00000149792|Vega:OTTHUMG00000165608 +741 ZNHIT2 MIM:604575|HGNC:HGNC:1177|Ensembl:ENSG00000174276|Vega:OTTHUMG00000165604 +744 MPPED2 MIM:600911|HGNC:HGNC:1180|Ensembl:ENSG00000066382|Vega:OTTHUMG00000166159 +745 MYRF MIM:608329|HGNC:HGNC:1181|Ensembl:ENSG00000124920|Vega:OTTHUMG00000168161 +746 TMEM258 HGNC:HGNC:1164|Ensembl:ENSG00000134825|Vega:OTTHUMG00000168172 +747 DAGLA MIM:614015|HGNC:HGNC:1165|Ensembl:ENSG00000134780|Vega:OTTHUMG00000168160 +750 GAS8-AS1 MIM:605179|HGNC:HGNC:1197 +752 FMNL1 MIM:604656|HGNC:HGNC:1212|Ensembl:ENSG00000184922|Vega:OTTHUMG00000180196 +753 LDLRAD4 MIM:606571|HGNC:HGNC:1224|Ensembl:ENSG00000168675|Vega:OTTHUMG00000181925 +754 PTTG1IP MIM:603784|HGNC:HGNC:13524|Ensembl:ENSG00000183255|Vega:OTTHUMG00000090254 +755 C21orf2 MIM:603191|HGNC:HGNC:1260|Ensembl:ENSG00000160226|Vega:OTTHUMG00000086909 +757 TMEM50B HGNC:HGNC:1280|Ensembl:ENSG00000142188|Vega:OTTHUMG00000065286 +758 MPPED1 MIM:602112|HGNC:HGNC:1306|Ensembl:ENSG00000186732|Vega:OTTHUMG00000150566 +759 CA1 MIM:114800|HGNC:HGNC:1368|Ensembl:ENSG00000133742|Vega:OTTHUMG00000164941 +760 CA2 MIM:611492|HGNC:HGNC:1373|Ensembl:ENSG00000104267|Vega:OTTHUMG00000164944 +761 CA3 MIM:114750|HGNC:HGNC:1374|Ensembl:ENSG00000164879|Vega:OTTHUMG00000164942 +762 CA4 MIM:114760|HGNC:HGNC:1375|Ensembl:ENSG00000167434|Vega:OTTHUMG00000179987 +763 CA5A MIM:114761|HGNC:HGNC:1377|Ensembl:ENSG00000174990|Vega:OTTHUMG00000137677 +764 CA5AP1 HGNC:HGNC:1379 +765 CA6 MIM:114780|HGNC:HGNC:1380|Ensembl:ENSG00000131686|Vega:OTTHUMG00000001763 +766 CA7 MIM:114770|HGNC:HGNC:1381|Ensembl:ENSG00000168748|Vega:OTTHUMG00000137524 +767 CA8 MIM:114815|HGNC:HGNC:1382|Ensembl:ENSG00000178538|Vega:OTTHUMG00000165325 +768 CA9 MIM:603179|HGNC:HGNC:1383|Ensembl:ENSG00000107159|Vega:OTTHUMG00000021029 +770 CA11 MIM:604644|HGNC:HGNC:1370|Ensembl:ENSG00000063180|Vega:OTTHUMG00000183320 +771 CA12 MIM:603263|HGNC:HGNC:1371|Ensembl:ENSG00000074410|Vega:OTTHUMG00000132881 +772 CACD MIM:215500|HGNC:HGNC:1387 +773 CACNA1A MIM:601011|HGNC:HGNC:1388|Ensembl:ENSG00000141837|Vega:OTTHUMG00000044590 +774 CACNA1B MIM:601012|HGNC:HGNC:1389|Ensembl:ENSG00000148408|Vega:OTTHUMG00000021002 +775 CACNA1C MIM:114205|HGNC:HGNC:1390|Ensembl:ENSG00000151067|Vega:OTTHUMG00000150243 +776 CACNA1D MIM:114206|HGNC:HGNC:1391|Ensembl:ENSG00000157388|Vega:OTTHUMG00000158278 +777 CACNA1E MIM:601013|HGNC:HGNC:1392|Ensembl:ENSG00000198216|Vega:OTTHUMG00000037301 +778 CACNA1F MIM:300110|HGNC:HGNC:1393|Ensembl:ENSG00000102001|Vega:OTTHUMG00000022703 +779 CACNA1S MIM:114208|HGNC:HGNC:1397|Ensembl:ENSG00000081248|Vega:OTTHUMG00000035784 +780 DDR1 MIM:600408|HGNC:HGNC:2730|Ensembl:ENSG00000204580|Vega:OTTHUMG00000031236 +781 CACNA2D1 MIM:114204|HGNC:HGNC:1399|Ensembl:ENSG00000153956|Vega:OTTHUMG00000023622 +782 CACNB1 MIM:114207|HGNC:HGNC:1401|Ensembl:ENSG00000067191|Vega:OTTHUMG00000133217 +783 CACNB2 MIM:600003|HGNC:HGNC:1402|Ensembl:ENSG00000165995|Vega:OTTHUMG00000017764 +784 CACNB3 MIM:601958|HGNC:HGNC:1403|Ensembl:ENSG00000167535|Vega:OTTHUMG00000170398 +785 CACNB4 MIM:601949|HGNC:HGNC:1404|Ensembl:ENSG00000182389|Ensembl:ENSG00000283228|Vega:OTTHUMG00000155091|Vega:OTTHUMG00000191700 +786 CACNG1 MIM:114209|HGNC:HGNC:1405|Ensembl:ENSG00000108878|Vega:OTTHUMG00000179553 +788 SLC25A20 MIM:613698|HGNC:HGNC:1421|Ensembl:ENSG00000178537|Vega:OTTHUMG00000133538 +789 SLC25A20P1 HGNC:HGNC:1422 +790 CAD MIM:114010|HGNC:HGNC:1424|Ensembl:ENSG00000084774|Vega:OTTHUMG00000097070 +793 CALB1 MIM:114050|HGNC:HGNC:1434|Ensembl:ENSG00000104327|Vega:OTTHUMG00000134314 +794 CALB2 MIM:114051|HGNC:HGNC:1435|Ensembl:ENSG00000172137|Vega:OTTHUMG00000137589 +795 S100G MIM:302020|HGNC:HGNC:1436|Ensembl:ENSG00000169906|Vega:OTTHUMG00000021194 +796 CALCA MIM:114130|HGNC:HGNC:1437|Ensembl:ENSG00000110680|Vega:OTTHUMG00000159731 +797 CALCB MIM:114160|HGNC:HGNC:1438|Ensembl:ENSG00000175868|Vega:OTTHUMG00000164629 +798 CALCP HGNC:HGNC:1439 +799 CALCR MIM:114131|HGNC:HGNC:1440|Ensembl:ENSG00000004948|Vega:OTTHUMG00000023599 +800 CALD1 MIM:114213|HGNC:HGNC:1441|Ensembl:ENSG00000122786|Vega:OTTHUMG00000155407 +801 CALM1 MIM:114180|HGNC:HGNC:1442|Ensembl:ENSG00000198668|Vega:OTTHUMG00000171044 +802 CALM1P1 HGNC:HGNC:1443 +804 CALM1P2 HGNC:HGNC:1444 +805 CALM2 MIM:114182|HGNC:HGNC:1445|Ensembl:ENSG00000143933|Vega:OTTHUMG00000128850 +806 CALM2P2 HGNC:HGNC:1447 +807 CALM2P3 HGNC:HGNC:1448 +808 CALM3 MIM:114183|HGNC:HGNC:1449|Ensembl:ENSG00000160014|Vega:OTTHUMG00000133517 +810 CALML3 MIM:114184|HGNC:HGNC:1452|Ensembl:ENSG00000178363|Vega:OTTHUMG00000017597 +811 CALR MIM:109091|HGNC:HGNC:1455|Ensembl:ENSG00000179218|Vega:OTTHUMG00000180574 +813 CALU MIM:603420|HGNC:HGNC:1458|Ensembl:ENSG00000128595|Vega:OTTHUMG00000158274 +814 CAMK4 MIM:114080|HGNC:HGNC:1464|Ensembl:ENSG00000152495|Vega:OTTHUMG00000128792 +815 CAMK2A MIM:114078|HGNC:HGNC:1460|Ensembl:ENSG00000070808|Vega:OTTHUMG00000134281 +816 CAMK2B MIM:607707|HGNC:HGNC:1461|Ensembl:ENSG00000058404|Vega:OTTHUMG00000023491 +817 CAMK2D MIM:607708|HGNC:HGNC:1462|Ensembl:ENSG00000145349|Vega:OTTHUMG00000132910 +818 CAMK2G MIM:602123|HGNC:HGNC:1463|Ensembl:ENSG00000148660|Vega:OTTHUMG00000018492 +819 CAMLG MIM:601118|HGNC:HGNC:1471|Ensembl:ENSG00000164615|Vega:OTTHUMG00000129116 +820 CAMP MIM:600474|HGNC:HGNC:1472|Ensembl:ENSG00000164047|Vega:OTTHUMG00000133526 +821 CANX MIM:114217|HGNC:HGNC:1473|Ensembl:ENSG00000127022|Vega:OTTHUMG00000130910 +822 CAPG MIM:153615|HGNC:HGNC:1474|Ensembl:ENSG00000042493|Vega:OTTHUMG00000130183 +823 CAPN1 MIM:114220|HGNC:HGNC:1476|Ensembl:ENSG00000014216|Vega:OTTHUMG00000165614 +824 CAPN2 MIM:114230|HGNC:HGNC:1479|Ensembl:ENSG00000162909|Vega:OTTHUMG00000037376 +825 CAPN3 MIM:114240|HGNC:HGNC:1480|Ensembl:ENSG00000092529|Vega:OTTHUMG00000130619 +826 CAPNS1 MIM:114170|HGNC:HGNC:1481|Ensembl:ENSG00000126247|Vega:OTTHUMG00000160811 +827 CAPN6 MIM:300146|HGNC:HGNC:1483|Ensembl:ENSG00000077274|Vega:OTTHUMG00000022203 +828 CAPS MIM:114212|HGNC:HGNC:1487|Ensembl:ENSG00000105519|Vega:OTTHUMG00000180619 +829 CAPZA1 MIM:601580|HGNC:HGNC:1488|Ensembl:ENSG00000116489|Vega:OTTHUMG00000011769 +830 CAPZA2 MIM:601571|HGNC:HGNC:1490|Ensembl:ENSG00000198898|Vega:OTTHUMG00000023185 +831 CAST MIM:114090|HGNC:HGNC:1515|Ensembl:ENSG00000153113|Vega:OTTHUMG00000128413 +832 CAPZB MIM:601572|HGNC:HGNC:1491|Ensembl:ENSG00000077549|Vega:OTTHUMG00000002556 +833 CARS MIM:123859|HGNC:HGNC:1493|Ensembl:ENSG00000110619|Vega:OTTHUMG00000010927 +834 CASP1 MIM:147678|HGNC:HGNC:1499|Ensembl:ENSG00000137752|Vega:OTTHUMG00000048072 +835 CASP2 MIM:600639|HGNC:HGNC:1503|Ensembl:ENSG00000106144|Vega:OTTHUMG00000023641 +836 CASP3 MIM:600636|HGNC:HGNC:1504|Ensembl:ENSG00000164305|Vega:OTTHUMG00000133681 +837 CASP4 MIM:602664|HGNC:HGNC:1505|Ensembl:ENSG00000196954|Vega:OTTHUMG00000166078 +838 CASP5 MIM:602665|HGNC:HGNC:1506|Ensembl:ENSG00000137757|Vega:OTTHUMG00000048073 +839 CASP6 MIM:601532|HGNC:HGNC:1507|Ensembl:ENSG00000138794|Vega:OTTHUMG00000131914 +840 CASP7 MIM:601761|HGNC:HGNC:1508|Ensembl:ENSG00000165806|Vega:OTTHUMG00000019076 +841 CASP8 MIM:601763|HGNC:HGNC:1509|Ensembl:ENSG00000064012|Vega:OTTHUMG00000132821 +842 CASP9 MIM:602234|HGNC:HGNC:1511|Ensembl:ENSG00000132906|Vega:OTTHUMG00000002256 +843 CASP10 MIM:601762|HGNC:HGNC:1500|Ensembl:ENSG00000003400|Vega:OTTHUMG00000132818 +844 CASQ1 MIM:114250|HGNC:HGNC:1512|Ensembl:ENSG00000143318|Vega:OTTHUMG00000031607 +845 CASQ2 MIM:114251|HGNC:HGNC:1513|Ensembl:ENSG00000118729|Vega:OTTHUMG00000011970 +846 CASR MIM:601199|HGNC:HGNC:1514|Ensembl:ENSG00000036828 +847 CAT MIM:115500|HGNC:HGNC:1516|Ensembl:ENSG00000121691|Vega:OTTHUMG00000044353 +856 CATR1 MIM:600676|HGNC:HGNC:1525 +857 CAV1 MIM:601047|HGNC:HGNC:1527|Ensembl:ENSG00000105974|Vega:OTTHUMG00000023413 +858 CAV2 MIM:601048|HGNC:HGNC:1528|Ensembl:ENSG00000105971|Vega:OTTHUMG00000023414 +859 CAV3 MIM:601253|HGNC:HGNC:1529|Ensembl:ENSG00000182533|Vega:OTTHUMG00000090519 +860 RUNX2 MIM:600211|HGNC:HGNC:10472|Ensembl:ENSG00000124813|Vega:OTTHUMG00000014774 +861 RUNX1 MIM:151385|HGNC:HGNC:10471|Ensembl:ENSG00000159216|Vega:OTTHUMG00000086299 +862 RUNX1T1 MIM:133435|HGNC:HGNC:1535|Ensembl:ENSG00000079102|Vega:OTTHUMG00000164066 +863 CBFA2T3 MIM:603870|HGNC:HGNC:1537|Ensembl:ENSG00000129993|Vega:OTTHUMG00000137864 +864 RUNX3 MIM:600210|HGNC:HGNC:10473|Ensembl:ENSG00000020633|Vega:OTTHUMG00000003316 +865 CBFB MIM:121360|HGNC:HGNC:1539|Ensembl:ENSG00000067955|Vega:OTTHUMG00000137520 +866 SERPINA6 MIM:122500|HGNC:HGNC:1540|Ensembl:ENSG00000170099|Vega:OTTHUMG00000171346 +867 CBL MIM:165360|HGNC:HGNC:1541|Ensembl:ENSG00000110395|Vega:OTTHUMG00000166170 +868 CBLB MIM:604491|HGNC:HGNC:1542|Ensembl:ENSG00000114423|Vega:OTTHUMG00000150654 +869 CBLN1 MIM:600432|HGNC:HGNC:1543|Ensembl:ENSG00000102924|Vega:OTTHUMG00000133148 +871 SERPINH1 MIM:600943|HGNC:HGNC:1546|Ensembl:ENSG00000149257|Vega:OTTHUMG00000165362 +873 CBR1 MIM:114830|HGNC:HGNC:1548|Ensembl:ENSG00000159228|Vega:OTTHUMG00000086618 +874 CBR3 MIM:603608|HGNC:HGNC:1549|Ensembl:ENSG00000159231|Vega:OTTHUMG00000086617 +875 CBS MIM:613381|HGNC:HGNC:1550|Ensembl:ENSG00000160200|Vega:OTTHUMG00000086834 +878 CCA1 MIM:115660|HGNC:HGNC:1559 +881 CCIN MIM:603960|HGNC:HGNC:1568|Ensembl:ENSG00000185972|Vega:OTTHUMG00000019901 +882 CCAL1 MIM:600668|HGNC:HGNC:1561 +883 KYAT1 MIM:600547|HGNC:HGNC:1564|Ensembl:ENSG00000171097|Vega:OTTHUMG00000020767 +885 CCK MIM:118440|HGNC:HGNC:1569|Ensembl:ENSG00000187094|Vega:OTTHUMG00000131796 +886 CCKAR MIM:118444|HGNC:HGNC:1570|Ensembl:ENSG00000163394|Vega:OTTHUMG00000128567 +887 CCKBR MIM:118445|HGNC:HGNC:1571|Ensembl:ENSG00000110148|Vega:OTTHUMG00000133380 +889 KRIT1 MIM:604214|HGNC:HGNC:1573|Ensembl:ENSG00000001631|Vega:OTTHUMG00000131187 +890 CCNA2 MIM:123835|HGNC:HGNC:1578|Ensembl:ENSG00000145386|Vega:OTTHUMG00000133072 +891 CCNB1 MIM:123836|HGNC:HGNC:1579|Ensembl:ENSG00000134057|Vega:OTTHUMG00000097817 +892 CCNC MIM:123838|HGNC:HGNC:1581|Ensembl:ENSG00000112237|Vega:OTTHUMG00000015268 +894 CCND2 MIM:123833|HGNC:HGNC:1583|Ensembl:ENSG00000118971|Vega:OTTHUMG00000168123 +895 CCND2P1 HGNC:HGNC:1584 +896 CCND3 MIM:123834|HGNC:HGNC:1585|Ensembl:ENSG00000112576|Vega:OTTHUMG00000014690 +897 CCND3P1 HGNC:HGNC:1586 +898 CCNE1 MIM:123837|HGNC:HGNC:1589|Ensembl:ENSG00000105173|Vega:OTTHUMG00000177626 +899 CCNF MIM:600227|HGNC:HGNC:1591|Ensembl:ENSG00000162063|Vega:OTTHUMG00000128858 +900 CCNG1 MIM:601578|HGNC:HGNC:1592|Ensembl:ENSG00000113328|Vega:OTTHUMG00000130380 +901 CCNG2 MIM:603203|HGNC:HGNC:1593|Ensembl:ENSG00000138764|Vega:OTTHUMG00000130100 +902 CCNH MIM:601953|HGNC:HGNC:1594|Ensembl:ENSG00000134480|Vega:OTTHUMG00000119077 +904 CCNT1 MIM:143055|HGNC:HGNC:1599|Ensembl:ENSG00000129315|Vega:OTTHUMG00000170393 +905 CCNT2 MIM:603862|HGNC:HGNC:1600|Ensembl:ENSG00000082258|Vega:OTTHUMG00000131712 +907 CCT MIM:302200|HGNC:HGNC:1614 +908 CCT6A MIM:104613|HGNC:HGNC:1620|Ensembl:ENSG00000146731|Vega:OTTHUMG00000022842 +909 CD1A MIM:188370|HGNC:HGNC:1634|Ensembl:ENSG00000158477|Vega:OTTHUMG00000017512 +910 CD1B MIM:188360|HGNC:HGNC:1635|Ensembl:ENSG00000158485|Vega:OTTHUMG00000017513 +911 CD1C MIM:188340|HGNC:HGNC:1636|Ensembl:ENSG00000158481|Vega:OTTHUMG00000017514 +912 CD1D MIM:188410|HGNC:HGNC:1637|Ensembl:ENSG00000158473|Vega:OTTHUMG00000022436 +913 CD1E MIM:188411|HGNC:HGNC:1638|Ensembl:ENSG00000158488|Vega:OTTHUMG00000017515 +914 CD2 MIM:186990|HGNC:HGNC:1639|Ensembl:ENSG00000116824|Vega:OTTHUMG00000022750 +915 CD3D MIM:186790|HGNC:HGNC:1673|Ensembl:ENSG00000167286|Vega:OTTHUMG00000166970 +916 CD3E MIM:186830|HGNC:HGNC:1674|Ensembl:ENSG00000198851|Vega:OTTHUMG00000166968 +917 CD3G MIM:186740|HGNC:HGNC:1675|Ensembl:ENSG00000160654|Vega:OTTHUMG00000166971 +919 CD247 MIM:186780|HGNC:HGNC:1677|Ensembl:ENSG00000198821|Vega:OTTHUMG00000034593 +920 CD4 MIM:186940|HGNC:HGNC:1678|Ensembl:ENSG00000010610|Vega:OTTHUMG00000168514 +921 CD5 MIM:153340|HGNC:HGNC:1685|Ensembl:ENSG00000110448|Vega:OTTHUMG00000167825 +922 CD5L MIM:602592|HGNC:HGNC:1690|Ensembl:ENSG00000073754|Vega:OTTHUMG00000022440 +923 CD6 MIM:186720|HGNC:HGNC:1691|Ensembl:ENSG00000013725|Vega:OTTHUMG00000167823 +924 CD7 MIM:186820|HGNC:HGNC:1695|Ensembl:ENSG00000173762|Vega:OTTHUMG00000178662 +925 CD8A MIM:186910|HGNC:HGNC:1706|Ensembl:ENSG00000153563|Vega:OTTHUMG00000130265 +926 CD8B MIM:186730|HGNC:HGNC:1707|Ensembl:ENSG00000172116|Vega:OTTHUMG00000130264 +927 CD8B2 HGNC:HGNC:1708 +928 CD9 MIM:143030|HGNC:HGNC:1709|Ensembl:ENSG00000010278|Vega:OTTHUMG00000044400 +929 CD14 MIM:158120|HGNC:HGNC:1628|Ensembl:ENSG00000170458|Vega:OTTHUMG00000129507 +930 CD19 MIM:107265|HGNC:HGNC:1633|Ensembl:ENSG00000177455|Vega:OTTHUMG00000097049 +931 MS4A1 MIM:112210|HGNC:HGNC:7315|Ensembl:ENSG00000156738|Vega:OTTHUMG00000167614 +932 MS4A3 MIM:606498|HGNC:HGNC:7317|Ensembl:ENSG00000149516|Vega:OTTHUMG00000167380 +933 CD22 MIM:107266|HGNC:HGNC:1643|Ensembl:ENSG00000012124|Vega:OTTHUMG00000183298 +935 CD24P1 HGNC:HGNC:1646 +936 CD24P2 HGNC:HGNC:1647 +937 CD24P3 HGNC:HGNC:1648 +938 CD24P4 HGNC:HGNC:1649 +939 CD27 MIM:186711|HGNC:HGNC:11922|Ensembl:ENSG00000139193|Vega:OTTHUMG00000168316 +940 CD28 MIM:186760|HGNC:HGNC:1653|Ensembl:ENSG00000178562|Vega:OTTHUMG00000132878 +941 CD80 MIM:112203|HGNC:HGNC:1700|Ensembl:ENSG00000121594|Vega:OTTHUMG00000159419 +942 CD86 MIM:601020|HGNC:HGNC:1705|Ensembl:ENSG00000114013|Vega:OTTHUMG00000159482 +943 TNFRSF8 MIM:153243|HGNC:HGNC:11923|Ensembl:ENSG00000120949|Vega:OTTHUMG00000001827 +944 TNFSF8 MIM:603875|HGNC:HGNC:11938|Ensembl:ENSG00000106952|Vega:OTTHUMG00000021025 +945 CD33 MIM:159590|HGNC:HGNC:1659|Ensembl:ENSG00000105383|Vega:OTTHUMG00000182891 +946 SIGLEC6 MIM:604405|HGNC:HGNC:10875|Ensembl:ENSG00000105492|Vega:OTTHUMG00000133571 +947 CD34 MIM:142230|HGNC:HGNC:1662|Ensembl:ENSG00000174059|Vega:OTTHUMG00000036565 +948 CD36 MIM:173510|HGNC:HGNC:1663|Ensembl:ENSG00000135218|Vega:OTTHUMG00000155383 +949 SCARB1 MIM:601040|HGNC:HGNC:1664|Ensembl:ENSG00000073060|Vega:OTTHUMG00000168544 +950 SCARB2 MIM:602257|HGNC:HGNC:1665|Ensembl:ENSG00000138760|Vega:OTTHUMG00000130099 +951 CD37 MIM:151523|HGNC:HGNC:1666|Ensembl:ENSG00000104894|Vega:OTTHUMG00000183183 +952 CD38 MIM:107270|HGNC:HGNC:1667|Ensembl:ENSG00000004468|Vega:OTTHUMG00000048206 +953 ENTPD1 MIM:601752|HGNC:HGNC:3363|Ensembl:ENSG00000138185|Vega:OTTHUMG00000018818 +954 ENTPD2 MIM:602012|HGNC:HGNC:3364|Ensembl:ENSG00000054179|Vega:OTTHUMG00000020953 +955 ENTPD6 MIM:603160|HGNC:HGNC:3368|Ensembl:ENSG00000197586|Vega:OTTHUMG00000032116 +956 ENTPD3 MIM:603161|HGNC:HGNC:3365|Ensembl:ENSG00000168032|Vega:OTTHUMG00000131390 +957 ENTPD5 MIM:603162|HGNC:HGNC:3367|Ensembl:ENSG00000187097|Vega:OTTHUMG00000171201 +958 CD40 MIM:109535|HGNC:HGNC:11919|Ensembl:ENSG00000101017|Vega:OTTHUMG00000033053 +959 CD40LG MIM:300386|HGNC:HGNC:11935|Ensembl:ENSG00000102245|Vega:OTTHUMG00000022512 +960 CD44 MIM:107269|HGNC:HGNC:1681|Ensembl:ENSG00000026508|Vega:OTTHUMG00000044388 +961 CD47 MIM:601028|HGNC:HGNC:1682|Ensembl:ENSG00000196776|Vega:OTTHUMG00000044216 +962 CD48 MIM:109530|HGNC:HGNC:1683|Ensembl:ENSG00000117091|Vega:OTTHUMG00000024009 +963 CD53 MIM:151525|HGNC:HGNC:1686|Ensembl:ENSG00000143119|Vega:OTTHUMG00000048020 +965 CD58 MIM:153420|HGNC:HGNC:1688|Ensembl:ENSG00000116815|Vega:OTTHUMG00000022749 +966 CD59 MIM:107271|HGNC:HGNC:1689|Ensembl:ENSG00000085063|Vega:OTTHUMG00000166270 +967 CD63 MIM:155740|HGNC:HGNC:1692|Ensembl:ENSG00000135404|Vega:OTTHUMG00000170454 +968 CD68 MIM:153634|HGNC:HGNC:1693|Ensembl:ENSG00000129226|Vega:OTTHUMG00000108146 +969 CD69 MIM:107273|HGNC:HGNC:1694|Ensembl:ENSG00000110848|Vega:OTTHUMG00000168481 +970 CD70 MIM:602840|HGNC:HGNC:11937|Ensembl:ENSG00000125726|Vega:OTTHUMG00000181834 +971 CD72 MIM:107272|HGNC:HGNC:1696|Ensembl:ENSG00000137101|Vega:OTTHUMG00000019870 +972 CD74 MIM:142790|HGNC:HGNC:1697|Ensembl:ENSG00000019582|Vega:OTTHUMG00000163559 +973 CD79A MIM:112205|HGNC:HGNC:1698|Ensembl:ENSG00000105369|Vega:OTTHUMG00000182678 +974 CD79B MIM:147245|HGNC:HGNC:1699|Ensembl:ENSG00000007312|Vega:OTTHUMG00000172294 +975 CD81 MIM:186845|HGNC:HGNC:1701|Ensembl:ENSG00000110651|Vega:OTTHUMG00000009892 +976 ADGRE5 MIM:601211|HGNC:HGNC:1711|Ensembl:ENSG00000123146|Vega:OTTHUMG00000182166 +977 CD151 MIM:602243|HGNC:HGNC:1630|Ensembl:ENSG00000177697|Vega:OTTHUMG00000133311 +978 CDA MIM:123920|HGNC:HGNC:1712|Ensembl:ENSG00000158825|Vega:OTTHUMG00000002845 +981 CDAN3 MIM:105600|HGNC:HGNC:1715 +982 CDB2 MIM:602082|HGNC:HGNC:1716 +983 CDK1 MIM:116940|HGNC:HGNC:1722|Ensembl:ENSG00000170312|Vega:OTTHUMG00000018290 +984 CDK11B MIM:176873|HGNC:HGNC:1729|Ensembl:ENSG00000248333|Vega:OTTHUMG00000078638 +987 LRBA MIM:606453|HGNC:HGNC:1742|Ensembl:ENSG00000198589|Vega:OTTHUMG00000161443 +988 CDC5L MIM:602868|HGNC:HGNC:1743|Ensembl:ENSG00000096401|Vega:OTTHUMG00000014767 +989 SEPT7 MIM:603151|HGNC:HGNC:1717|Ensembl:ENSG00000122545|Vega:OTTHUMG00000155063 +990 CDC6 MIM:602627|HGNC:HGNC:1744|Ensembl:ENSG00000094804|Vega:OTTHUMG00000133324 +991 CDC20 MIM:603618|HGNC:HGNC:1723|Ensembl:ENSG00000117399|Vega:OTTHUMG00000007420 +993 CDC25A MIM:116947|HGNC:HGNC:1725|Ensembl:ENSG00000164045|Vega:OTTHUMG00000133535 +994 CDC25B MIM:116949|HGNC:HGNC:1726|Ensembl:ENSG00000101224|Vega:OTTHUMG00000031764 +995 CDC25C MIM:157680|HGNC:HGNC:1727|Ensembl:ENSG00000158402|Vega:OTTHUMG00000129203 +996 CDC27 MIM:116946|HGNC:HGNC:1728|Ensembl:ENSG00000004897|Vega:OTTHUMG00000166429 +997 CDC34 MIM:116948|HGNC:HGNC:1734|Ensembl:ENSG00000099804|Vega:OTTHUMG00000180558 +998 CDC42 MIM:116952|HGNC:HGNC:1736|Ensembl:ENSG00000070831|Vega:OTTHUMG00000002753 +999 CDH1 MIM:192090|HGNC:HGNC:1748|Ensembl:ENSG00000039068|Vega:OTTHUMG00000137561 +1000 CDH2 MIM:114020|HGNC:HGNC:1759|Ensembl:ENSG00000170558|Vega:OTTHUMG00000059940 +1001 CDH3 MIM:114021|HGNC:HGNC:1762|Ensembl:ENSG00000062038|Vega:OTTHUMG00000137560 +1002 CDH4 MIM:603006|HGNC:HGNC:1763|Ensembl:ENSG00000179242|Vega:OTTHUMG00000032890 +1003 CDH5 MIM:601120|HGNC:HGNC:1764|Ensembl:ENSG00000179776|Vega:OTTHUMG00000137495 +1004 CDH6 MIM:603007|HGNC:HGNC:1765|Ensembl:ENSG00000113361|Vega:OTTHUMG00000090673 +1005 CDH7 MIM:605806|HGNC:HGNC:1766|Ensembl:ENSG00000081138|Vega:OTTHUMG00000132800 +1006 CDH8 MIM:603008|HGNC:HGNC:1767|Ensembl:ENSG00000150394|Vega:OTTHUMG00000137493 +1007 CDH9 MIM:609974|HGNC:HGNC:1768|Ensembl:ENSG00000113100|Vega:OTTHUMG00000090671 +1008 CDH10 MIM:604555|HGNC:HGNC:1749|Ensembl:ENSG00000040731|Vega:OTTHUMG00000090667 +1009 CDH11 MIM:600023|HGNC:HGNC:1750|Ensembl:ENSG00000140937|Vega:OTTHUMG00000137494 +1010 CDH12 MIM:600562|HGNC:HGNC:1751|Ensembl:ENSG00000154162|Vega:OTTHUMG00000090591 +1011 CDH12P2 HGNC:HGNC:1752 +1012 CDH13 MIM:601364|HGNC:HGNC:1753|Ensembl:ENSG00000140945|Vega:OTTHUMG00000176635 +1013 CDH15 MIM:114019|HGNC:HGNC:1754|Ensembl:ENSG00000129910|Vega:OTTHUMG00000138045 +1014 CDH16 MIM:603118|HGNC:HGNC:1755|Ensembl:ENSG00000166589|Vega:OTTHUMG00000137518 +1015 CDH17 MIM:603017|HGNC:HGNC:1756|Ensembl:ENSG00000079112|Vega:OTTHUMG00000164391 +1016 CDH18 MIM:603019|HGNC:HGNC:1757|Ensembl:ENSG00000145526|Vega:OTTHUMG00000090578 +1017 CDK2 MIM:116953|HGNC:HGNC:1771|Ensembl:ENSG00000123374|Vega:OTTHUMG00000170575 +1018 CDK3 MIM:123828|HGNC:HGNC:1772|Ensembl:ENSG00000250506|Vega:OTTHUMG00000154861 +1019 CDK4 MIM:123829|HGNC:HGNC:1773|Ensembl:ENSG00000135446|Vega:OTTHUMG00000170382 +1020 CDK5 MIM:123831|HGNC:HGNC:1774|Ensembl:ENSG00000164885|Vega:OTTHUMG00000158414 +1021 CDK6 MIM:603368|HGNC:HGNC:1777|Ensembl:ENSG00000105810|Vega:OTTHUMG00000131697 +1022 CDK7 MIM:601955|HGNC:HGNC:1778|Ensembl:ENSG00000134058|Vega:OTTHUMG00000099358 +1023 CDL2 HGNC:HGNC:1793 +1024 CDK8 MIM:603184|HGNC:HGNC:1779|Ensembl:ENSG00000132964|Vega:OTTHUMG00000016617 +1025 CDK9 MIM:603251|HGNC:HGNC:1780|Ensembl:ENSG00000136807|Vega:OTTHUMG00000020715 +1026 CDKN1A MIM:116899|HGNC:HGNC:1784|Ensembl:ENSG00000124762|Vega:OTTHUMG00000014603 +1027 CDKN1B MIM:600778|HGNC:HGNC:1785|Ensembl:ENSG00000111276|Vega:OTTHUMG00000149914 +1028 CDKN1C MIM:600856|HGNC:HGNC:1786|Ensembl:ENSG00000129757|Vega:OTTHUMG00000010040 +1029 CDKN2A MIM:600160|HGNC:HGNC:1787|Ensembl:ENSG00000147889|Vega:OTTHUMG00000019686 +1030 CDKN2B MIM:600431|HGNC:HGNC:1788|Ensembl:ENSG00000147883|Vega:OTTHUMG00000019691 +1031 CDKN2C MIM:603369|HGNC:HGNC:1789|Ensembl:ENSG00000123080|Vega:OTTHUMG00000008046 +1032 CDKN2D MIM:600927|HGNC:HGNC:1790|Ensembl:ENSG00000129355|Vega:OTTHUMG00000180583 +1033 CDKN3 MIM:123832|HGNC:HGNC:1791|Ensembl:ENSG00000100526|Vega:OTTHUMG00000140302 +1036 CDO1 MIM:603943|HGNC:HGNC:1795|Ensembl:ENSG00000129596|Vega:OTTHUMG00000128891 +1038 CDR1 MIM:302650|HGNC:HGNC:1798|Ensembl:ENSG00000184258|Vega:OTTHUMG00000137398 +1039 CDR2 MIM:117340|HGNC:HGNC:1799|Ensembl:ENSG00000140743|Vega:OTTHUMG00000175463 +1040 CDS1 MIM:603548|HGNC:HGNC:1800|Ensembl:ENSG00000163624|Vega:OTTHUMG00000130428 +1041 CDSN MIM:602593|HGNC:HGNC:1802|Ensembl:ENSG00000204539|Vega:OTTHUMG00000031150 +1043 CD52 MIM:114280|HGNC:HGNC:1804|Ensembl:ENSG00000169442|Vega:OTTHUMG00000003491 +1044 CDX1 MIM:600746|HGNC:HGNC:1805|Ensembl:ENSG00000113722|Vega:OTTHUMG00000169772 +1045 CDX2 MIM:600297|HGNC:HGNC:1806|Ensembl:ENSG00000165556|Vega:OTTHUMG00000016640 +1046 CDX4 MIM:300025|HGNC:HGNC:1808|Ensembl:ENSG00000131264|Vega:OTTHUMG00000021831 +1047 CLGN MIM:601858|HGNC:HGNC:2060|Ensembl:ENSG00000153132|Vega:OTTHUMG00000133414 +1048 CEACAM5 MIM:114890|HGNC:HGNC:1817|Ensembl:ENSG00000105388|Vega:OTTHUMG00000151061 +1050 CEBPA MIM:116897|HGNC:HGNC:1833|Ensembl:ENSG00000245848|Vega:OTTHUMG00000161461 +1051 CEBPB MIM:189965|HGNC:HGNC:1834|Ensembl:ENSG00000172216|Vega:OTTHUMG00000032715 +1052 CEBPD MIM:116898|HGNC:HGNC:1835|Ensembl:ENSG00000221869|Vega:OTTHUMG00000162290 +1053 CEBPE MIM:600749|HGNC:HGNC:1836|Ensembl:ENSG00000092067|Vega:OTTHUMG00000028719 +1054 CEBPG MIM:138972|HGNC:HGNC:1837|Ensembl:ENSG00000153879|Vega:OTTHUMG00000180469 +1055 CECR MIM:115470|HGNC:HGNC:1838 +1056 CEL MIM:114840|HGNC:HGNC:1848|Ensembl:ENSG00000170835|Vega:OTTHUMG00000020855 +1057 CELP HGNC:HGNC:1849|Ensembl:ENSG00000170827 +1058 CENPA MIM:117139|HGNC:HGNC:1851|Ensembl:ENSG00000115163|Vega:OTTHUMG00000097073 +1059 CENPB MIM:117140|HGNC:HGNC:1852|Ensembl:ENSG00000125817|Vega:OTTHUMG00000031761 +1060 CENPC MIM:117141|HGNC:HGNC:1854|Ensembl:ENSG00000145241|Vega:OTTHUMG00000160735 +1061 CENPCP1 HGNC:HGNC:1855 +1062 CENPE MIM:117143|HGNC:HGNC:1856|Ensembl:ENSG00000138778|Vega:OTTHUMG00000160980 +1063 CENPF MIM:600236|HGNC:HGNC:1857|Ensembl:ENSG00000117724|Vega:OTTHUMG00000036955 +1066 CES1 MIM:114835|HGNC:HGNC:1863|Ensembl:ENSG00000198848|Vega:OTTHUMG00000176718 +1068 CETN1 MIM:603187|HGNC:HGNC:1866|Ensembl:ENSG00000177143|Vega:OTTHUMG00000131471 +1069 CETN2 MIM:300006|HGNC:HGNC:1867|Ensembl:ENSG00000147400|Vega:OTTHUMG00000024246 +1070 CETN3 MIM:602907|HGNC:HGNC:1868|Ensembl:ENSG00000153140|Vega:OTTHUMG00000131326 +1071 CETP MIM:118470|HGNC:HGNC:1869|Ensembl:ENSG00000087237|Vega:OTTHUMG00000133279 +1072 CFL1 MIM:601442|HGNC:HGNC:1874|Ensembl:ENSG00000172757|Vega:OTTHUMG00000166602 +1073 CFL2 MIM:601443|HGNC:HGNC:1875|Ensembl:ENSG00000165410|Vega:OTTHUMG00000029536 +1074 CFL1P5 HGNC:HGNC:1877 +1075 CTSC MIM:602365|HGNC:HGNC:2528|Ensembl:ENSG00000109861|Vega:OTTHUMG00000167290 +1080 CFTR MIM:602421|HGNC:HGNC:1884|Ensembl:ENSG00000001626|Vega:OTTHUMG00000023076 +1081 CGA MIM:118850|HGNC:HGNC:1885|Ensembl:ENSG00000135346|Vega:OTTHUMG00000015161 +1082 CGB3 MIM:118860|HGNC:HGNC:1886|Ensembl:ENSG00000104827|Vega:OTTHUMG00000180605 +1083 CGF1 MIM:300082|HGNC:HGNC:1887 +1084 CEACAM3 MIM:609142|HGNC:HGNC:1815|Ensembl:ENSG00000170956|Vega:OTTHUMG00000150142 +1085 CEACAMP5 HGNC:HGNC:1827 +1086 CEACAMP11 HGNC:HGNC:1823 +1087 CEACAM7 HGNC:HGNC:1819|Ensembl:ENSG00000007306|Vega:OTTHUMG00000151063 +1088 CEACAM8 MIM:615747|HGNC:HGNC:1820|Ensembl:ENSG00000124469|Vega:OTTHUMG00000151124 +1089 CEACAM4 HGNC:HGNC:1816|Ensembl:ENSG00000105352|Vega:OTTHUMG00000151065 +1090 CEACAMP1 HGNC:HGNC:1821 +1091 CEACAMP2 HGNC:HGNC:1824 +1092 CEACAMP3 HGNC:HGNC:1825 +1093 CEACAMP4 HGNC:HGNC:1826 +1094 CEACAMP6 HGNC:HGNC:1828 +1095 CEACAMP7 HGNC:HGNC:1829 +1096 CEACAMP8 HGNC:HGNC:1830 +1097 CEACAMP9 HGNC:HGNC:1831 +1098 CEACAMP10 HGNC:HGNC:1822 +1101 CHAD MIM:602178|HGNC:HGNC:1909|Ensembl:ENSG00000136457|Vega:OTTHUMG00000162129 +1102 RCBTB2 MIM:603524|HGNC:HGNC:1914|Ensembl:ENSG00000136161|Vega:OTTHUMG00000016902 +1103 CHAT MIM:118490|HGNC:HGNC:1912|Ensembl:ENSG00000070748|Vega:OTTHUMG00000018198 +1104 RCC1 MIM:179710|HGNC:HGNC:1913|Ensembl:ENSG00000180198|Vega:OTTHUMG00000003645 +1105 CHD1 MIM:602118|HGNC:HGNC:1915|Ensembl:ENSG00000153922|Vega:OTTHUMG00000162744 +1106 CHD2 MIM:602119|HGNC:HGNC:1917|Ensembl:ENSG00000173575|Vega:OTTHUMG00000185958 +1107 CHD3 MIM:602120|HGNC:HGNC:1918|Ensembl:ENSG00000170004|Vega:OTTHUMG00000150427 +1108 CHD4 MIM:603277|HGNC:HGNC:1919|Ensembl:ENSG00000111642|Vega:OTTHUMG00000169164 +1109 AKR1C4 MIM:600451|HGNC:HGNC:387|Ensembl:ENSG00000198610|Vega:OTTHUMG00000017591 +1111 CHEK1 MIM:603078|HGNC:HGNC:1925|Ensembl:ENSG00000149554|Vega:OTTHUMG00000165853 +1112 FOXN3 MIM:602628|HGNC:HGNC:1928|Ensembl:ENSG00000053254|Vega:OTTHUMG00000170898 +1113 CHGA MIM:118910|HGNC:HGNC:1929|Ensembl:ENSG00000100604|Vega:OTTHUMG00000171225 +1114 CHGB MIM:118920|HGNC:HGNC:1930|Ensembl:ENSG00000089199|Vega:OTTHUMG00000031821 +1116 CHI3L1 MIM:601525|HGNC:HGNC:1932|Ensembl:ENSG00000133048|Vega:OTTHUMG00000042122 +1117 CHI3L2 MIM:601526|HGNC:HGNC:1933|Ensembl:ENSG00000064886|Vega:OTTHUMG00000012174 +1118 CHIT1 MIM:600031|HGNC:HGNC:1936|Ensembl:ENSG00000133063|Vega:OTTHUMG00000042126 +1119 CHKA MIM:118491|HGNC:HGNC:1937|Ensembl:ENSG00000110721|Vega:OTTHUMG00000167424 +1120 CHKB MIM:612395|HGNC:HGNC:1938|Ensembl:ENSG00000100288|Vega:OTTHUMG00000150275 +1121 CHM MIM:300390|HGNC:HGNC:1940|Ensembl:ENSG00000188419|Vega:OTTHUMG00000021937 +1122 CHML MIM:118825|HGNC:HGNC:1941|Ensembl:ENSG00000203668|Vega:OTTHUMG00000039690 +1123 CHN1 MIM:118423|HGNC:HGNC:1943|Ensembl:ENSG00000128656|Vega:OTTHUMG00000154225 +1124 CHN2 MIM:602857|HGNC:HGNC:1944|Ensembl:ENSG00000106069|Vega:OTTHUMG00000023063 +1125 CHR MIM:118840|HGNC:HGNC:1945 +1128 CHRM1 MIM:118510|HGNC:HGNC:1950|Ensembl:ENSG00000168539|Vega:OTTHUMG00000167765 +1129 CHRM2 MIM:118493|HGNC:HGNC:1951|Ensembl:ENSG00000181072|Vega:OTTHUMG00000155658 +1130 LYST MIM:606897|HGNC:HGNC:1968|Ensembl:ENSG00000143669|Vega:OTTHUMG00000040527 +1131 CHRM3 MIM:118494|HGNC:HGNC:1952|Ensembl:ENSG00000133019|Vega:OTTHUMG00000039649 +1132 CHRM4 MIM:118495|HGNC:HGNC:1953|Ensembl:ENSG00000180720|Vega:OTTHUMG00000154371 +1133 CHRM5 MIM:118496|HGNC:HGNC:1954|Ensembl:ENSG00000184984|Vega:OTTHUMG00000129369 +1134 CHRNA1 MIM:100690|HGNC:HGNC:1955|Ensembl:ENSG00000138435|Vega:OTTHUMG00000132357 +1135 CHRNA2 MIM:118502|HGNC:HGNC:1956|Ensembl:ENSG00000120903|Vega:OTTHUMG00000102083 +1136 CHRNA3 MIM:118503|HGNC:HGNC:1957|Ensembl:ENSG00000080644|Vega:OTTHUMG00000143863 +1137 CHRNA4 MIM:118504|HGNC:HGNC:1958|Ensembl:ENSG00000101204|Vega:OTTHUMG00000033080 +1138 CHRNA5 MIM:118505|HGNC:HGNC:1959|Ensembl:ENSG00000169684|Vega:OTTHUMG00000143858 +1139 CHRNA7 MIM:118511|HGNC:HGNC:1960|Ensembl:ENSG00000175344|Vega:OTTHUMG00000129285 +1140 CHRNB1 MIM:100710|HGNC:HGNC:1961|Ensembl:ENSG00000170175|Vega:OTTHUMG00000108139 +1141 CHRNB2 MIM:118507|HGNC:HGNC:1962|Ensembl:ENSG00000160716|Vega:OTTHUMG00000037262 +1142 CHRNB3 MIM:118508|HGNC:HGNC:1963|Ensembl:ENSG00000147432|Vega:OTTHUMG00000165262 +1143 CHRNB4 MIM:118509|HGNC:HGNC:1964|Ensembl:ENSG00000117971|Vega:OTTHUMG00000143860 +1144 CHRND MIM:100720|HGNC:HGNC:1965|Ensembl:ENSG00000135902|Vega:OTTHUMG00000133261 +1145 CHRNE MIM:100725|HGNC:HGNC:1966|Ensembl:ENSG00000108556|Vega:OTTHUMG00000090778 +1146 CHRNG MIM:100730|HGNC:HGNC:1967|Ensembl:ENSG00000196811|Vega:OTTHUMG00000153327 +1147 CHUK MIM:600664|HGNC:HGNC:1974|Ensembl:ENSG00000213341|Vega:OTTHUMG00000018899 +1149 CIDEA MIM:604440|HGNC:HGNC:1976|Ensembl:ENSG00000176194|Vega:OTTHUMG00000131691 +1152 CKB MIM:123280|HGNC:HGNC:1991|Ensembl:ENSG00000166165|Vega:OTTHUMG00000171786 +1153 CIRBP MIM:602649|HGNC:HGNC:1982|Ensembl:ENSG00000099622|Vega:OTTHUMG00000180145 +1154 CISH MIM:602441|HGNC:HGNC:1984|Ensembl:ENSG00000114737|Vega:OTTHUMG00000156853 +1155 TBCB MIM:601303|HGNC:HGNC:1989|Ensembl:ENSG00000105254|Vega:OTTHUMG00000048143 +1156 CKBE MIM:123270|HGNC:HGNC:1992 +1157 CKBP1 HGNC:HGNC:1993 +1158 CKM MIM:123310|HGNC:HGNC:1994|Ensembl:ENSG00000104879|Vega:OTTHUMG00000181782 +1159 CKMT1B MIM:123290|HGNC:HGNC:1995|Ensembl:ENSG00000237289|Vega:OTTHUMG00000059900 +1160 CKMT2 MIM:123295|HGNC:HGNC:1996|Ensembl:ENSG00000131730|Vega:OTTHUMG00000119013 +1161 ERCC8 MIM:609412|HGNC:HGNC:3439|Ensembl:ENSG00000049167|Vega:OTTHUMG00000097741 +1163 CKS1B MIM:116900|HGNC:HGNC:19083|Ensembl:ENSG00000173207|Vega:OTTHUMG00000037413 +1164 CKS2 MIM:116901|HGNC:HGNC:2000|Ensembl:ENSG00000123975|Vega:OTTHUMG00000020180 +1165 SCAR2 MIM:213200|HGNC:HGNC:2002 +1167 CLA3 MIM:608029|HGNC:HGNC:2004 +1173 AP2M1 MIM:601024|HGNC:HGNC:564|Ensembl:ENSG00000161203|Vega:OTTHUMG00000156822 +1174 AP1S1 MIM:603531|HGNC:HGNC:559|Ensembl:ENSG00000106367|Vega:OTTHUMG00000157103 +1175 AP2S1 MIM:602242|HGNC:HGNC:565|Ensembl:ENSG00000042753|Vega:OTTHUMG00000183437 +1176 AP3S1 MIM:601507|HGNC:HGNC:2013|Ensembl:ENSG00000177879|Vega:OTTHUMG00000128887 +1178 CLC MIM:153310|HGNC:HGNC:2014|Ensembl:ENSG00000105205|Vega:OTTHUMG00000183144 +1179 CLCA1 MIM:603906|HGNC:HGNC:2015|Ensembl:ENSG00000016490|Vega:OTTHUMG00000010254 +1180 CLCN1 MIM:118425|HGNC:HGNC:2019|Ensembl:ENSG00000188037|Vega:OTTHUMG00000152695 +1181 CLCN2 MIM:600570|HGNC:HGNC:2020|Ensembl:ENSG00000114859|Vega:OTTHUMG00000156747 +1182 CLCN3 MIM:600580|HGNC:HGNC:2021|Ensembl:ENSG00000109572|Vega:OTTHUMG00000160973 +1183 CLCN4 MIM:302910|HGNC:HGNC:2022|Ensembl:ENSG00000073464|Vega:OTTHUMG00000021125 +1184 CLCN5 MIM:300008|HGNC:HGNC:2023|Ensembl:ENSG00000171365|Vega:OTTHUMG00000021514 +1185 CLCN6 MIM:602726|HGNC:HGNC:2024|Ensembl:ENSG00000011021|Vega:OTTHUMG00000002299 +1186 CLCN7 MIM:602727|HGNC:HGNC:2025|Ensembl:ENSG00000103249|Vega:OTTHUMG00000044467 +1187 CLCNKA MIM:602024|HGNC:HGNC:2026|Ensembl:ENSG00000186510|Vega:OTTHUMG00000009529 +1188 CLCNKB MIM:602023|HGNC:HGNC:2027|Ensembl:ENSG00000184908|Vega:OTTHUMG00000009530 +1191 CLU MIM:185430|HGNC:HGNC:2095|Ensembl:ENSG00000120885|Vega:OTTHUMG00000102114 +1192 CLIC1 MIM:602872|HGNC:HGNC:2062|Ensembl:ENSG00000213719|Vega:OTTHUMG00000031103 +1193 CLIC2 MIM:300138|HGNC:HGNC:2063|Ensembl:ENSG00000155962|Vega:OTTHUMG00000022660 +1195 CLK1 MIM:601951|HGNC:HGNC:2068|Ensembl:ENSG00000013441|Vega:OTTHUMG00000132784 +1196 CLK2 MIM:602989|HGNC:HGNC:2069|Ensembl:ENSG00000176444|Vega:OTTHUMG00000035873 +1197 CLK2P1 HGNC:HGNC:2070 +1198 CLK3 MIM:602990|HGNC:HGNC:2071|Ensembl:ENSG00000179335|Vega:OTTHUMG00000141320 +1200 TPP1 MIM:607998|HGNC:HGNC:2073|Ensembl:ENSG00000166340|Vega:OTTHUMG00000133404 +1201 CLN3 MIM:607042|HGNC:HGNC:2074|Ensembl:ENSG00000188603|Ensembl:ENSG00000261832|Vega:OTTHUMG00000097024|Vega:OTTHUMG00000175737 +1203 CLN5 MIM:608102|HGNC:HGNC:2076|Ensembl:ENSG00000102805|Vega:OTTHUMG00000017100 +1204 CLNS1AP1 HGNC:HGNC:2081 +1207 CLNS1A MIM:602158|HGNC:HGNC:2080|Ensembl:ENSG00000074201|Vega:OTTHUMG00000165143 +1208 CLPS MIM:120105|HGNC:HGNC:2085|Ensembl:ENSG00000137392|Vega:OTTHUMG00000014578 +1209 CLPTM1 MIM:604783|HGNC:HGNC:2087|Ensembl:ENSG00000104853|Vega:OTTHUMG00000180849 +1211 CLTA MIM:118960|HGNC:HGNC:2090|Ensembl:ENSG00000122705|Vega:OTTHUMG00000019896 +1212 CLTB MIM:118970|HGNC:HGNC:2091|Ensembl:ENSG00000175416|Vega:OTTHUMG00000130662 +1213 CLTC MIM:118955|HGNC:HGNC:2092|Ensembl:ENSG00000141367|Vega:OTTHUMG00000134279 +1215 CMA1 MIM:118938|HGNC:HGNC:2097|Ensembl:ENSG00000092009|Vega:OTTHUMG00000140181 +1218 CMD1B MIM:600884|HGNC:HGNC:2102 +1222 CMD1F MIM:602067|HGNC:HGNC:2106 +1230 CCR1 MIM:601159|HGNC:HGNC:1602|Ensembl:ENSG00000163823|Vega:OTTHUMG00000133451 +1232 CCR3 MIM:601268|HGNC:HGNC:1604|Ensembl:ENSG00000183625|Vega:OTTHUMG00000133484 +1233 CCR4 MIM:604836|HGNC:HGNC:1605|Ensembl:ENSG00000183813|Vega:OTTHUMG00000130752 +1234 CCR5 MIM:601373|HGNC:HGNC:1606|Ensembl:ENSG00000160791|Vega:OTTHUMG00000133481 +1235 CCR6 MIM:601835|HGNC:HGNC:1607|Ensembl:ENSG00000112486|Vega:OTTHUMG00000016015 +1236 CCR7 MIM:600242|HGNC:HGNC:1608|Ensembl:ENSG00000126353|Vega:OTTHUMG00000133375 +1237 CCR8 MIM:601834|HGNC:HGNC:1609|Ensembl:ENSG00000179934|Vega:OTTHUMG00000131290 +1238 ACKR2 MIM:602648|HGNC:HGNC:1565|Ensembl:ENSG00000144648|Vega:OTTHUMG00000186377 +1240 CMKLR1 MIM:602351|HGNC:HGNC:2121|Ensembl:ENSG00000174600|Vega:OTTHUMG00000169576 +1241 LTB4R MIM:601531|HGNC:HGNC:6713|Ensembl:ENSG00000213903|Vega:OTTHUMG00000029346 +1243 CMM MIM:155600|HGNC:HGNC:2124 +1244 ABCC2 MIM:601107|HGNC:HGNC:53|Ensembl:ENSG00000023839|Vega:OTTHUMG00000018895 +1245 CMR1A HGNC:HGNC:2126 +1246 CMR2A HGNC:HGNC:2127 +1247 CMR3A HGNC:HGNC:2128 +1253 CMTX2 MIM:302801|HGNC:HGNC:2137 +1254 CMTX3 MIM:302802|HGNC:HGNC:2138 +1255 CNA1 MIM:121400|HGNC:HGNC:2139 +1257 CNC2 MIM:605244|HGNC:HGNC:2141 +1258 CNGB1 MIM:600724|HGNC:HGNC:2151|Ensembl:ENSG00000070729|Vega:OTTHUMG00000154810 +1259 CNGA1 MIM:123825|HGNC:HGNC:2148|Ensembl:ENSG00000198515|Vega:OTTHUMG00000160668 +1260 CNGA2 MIM:300338|HGNC:HGNC:2149|Ensembl:ENSG00000183862|Vega:OTTHUMG00000024173 +1261 CNGA3 MIM:600053|HGNC:HGNC:2150|Ensembl:ENSG00000144191|Vega:OTTHUMG00000130561 +1262 CNGA4 MIM:609472|HGNC:HGNC:2152|Ensembl:ENSG00000132259|Vega:OTTHUMG00000165379 +1263 PLK3 MIM:602913|HGNC:HGNC:2154|Ensembl:ENSG00000173846|Vega:OTTHUMG00000008491 +1264 CNN1 MIM:600806|HGNC:HGNC:2155|Ensembl:ENSG00000130176|Vega:OTTHUMG00000182033 +1265 CNN2 MIM:602373|HGNC:HGNC:2156|Ensembl:ENSG00000064666|Vega:OTTHUMG00000172729 +1266 CNN3 MIM:602374|HGNC:HGNC:2157|Ensembl:ENSG00000117519|Vega:OTTHUMG00000010783 +1267 CNP MIM:123830|HGNC:HGNC:2158|Ensembl:ENSG00000173786|Vega:OTTHUMG00000133502 +1268 CNR1 MIM:114610|HGNC:HGNC:2159|Ensembl:ENSG00000118432|Vega:OTTHUMG00000015184 +1269 CNR2 MIM:605051|HGNC:HGNC:2160|Ensembl:ENSG00000188822|Vega:OTTHUMG00000013892 +1270 CNTF MIM:118945|HGNC:HGNC:2169|Ensembl:ENSG00000242689|Vega:OTTHUMG00000137476 +1271 CNTFR MIM:118946|HGNC:HGNC:2170|Ensembl:ENSG00000122756|Vega:OTTHUMG00000019821 +1272 CNTN1 MIM:600016|HGNC:HGNC:2171|Ensembl:ENSG00000018236|Vega:OTTHUMG00000169362 +1275 COD2 MIM:300085|HGNC:HGNC:2182 +1277 COL1A1 MIM:120150|HGNC:HGNC:2197|Ensembl:ENSG00000108821|Vega:OTTHUMG00000148674 +1278 COL1A2 MIM:120160|HGNC:HGNC:2198|Ensembl:ENSG00000164692|Vega:OTTHUMG00000148675 +1279 COL1AR MIM:120340|HGNC:HGNC:2199 +1280 COL2A1 MIM:120140|HGNC:HGNC:2200|Ensembl:ENSG00000139219|Vega:OTTHUMG00000149896 +1281 COL3A1 MIM:120180|HGNC:HGNC:2201|Ensembl:ENSG00000168542|Vega:OTTHUMG00000132648 +1282 COL4A1 MIM:120130|HGNC:HGNC:2202|Ensembl:ENSG00000187498|Vega:OTTHUMG00000017342 +1283 CTD MIM:300216|HGNC:HGNC:2497 +1284 COL4A2 MIM:120090|HGNC:HGNC:2203|Ensembl:ENSG00000134871|Vega:OTTHUMG00000017344 +1285 COL4A3 MIM:120070|HGNC:HGNC:2204|Ensembl:ENSG00000169031|Vega:OTTHUMG00000149891 +1286 COL4A4 MIM:120131|HGNC:HGNC:2206|Ensembl:ENSG00000081052|Vega:OTTHUMG00000149892 +1287 COL4A5 MIM:303630|HGNC:HGNC:2207|Ensembl:ENSG00000188153|Vega:OTTHUMG00000022182 +1288 COL4A6 MIM:303631|HGNC:HGNC:2208|Ensembl:ENSG00000197565|Vega:OTTHUMG00000022179 +1289 COL5A1 MIM:120215|HGNC:HGNC:2209|Ensembl:ENSG00000130635|Vega:OTTHUMG00000020891 +1290 COL5A2 MIM:120190|HGNC:HGNC:2210|Ensembl:ENSG00000204262|Vega:OTTHUMG00000149842 +1291 COL6A1 MIM:120220|HGNC:HGNC:2211|Ensembl:ENSG00000142156|Vega:OTTHUMG00000090440 +1292 COL6A2 MIM:120240|HGNC:HGNC:2212|Ensembl:ENSG00000142173|Vega:OTTHUMG00000090489 +1293 COL6A3 MIM:120250|HGNC:HGNC:2213|Ensembl:ENSG00000163359|Vega:OTTHUMG00000150020 +1294 COL7A1 MIM:120120|HGNC:HGNC:2214|Ensembl:ENSG00000114270|Vega:OTTHUMG00000133541 +1295 COL8A1 MIM:120251|HGNC:HGNC:2215|Ensembl:ENSG00000144810|Vega:OTTHUMG00000148669 +1296 COL8A2 MIM:120252|HGNC:HGNC:2216|Ensembl:ENSG00000171812|Vega:OTTHUMG00000007665 +1297 COL9A1 MIM:120210|HGNC:HGNC:2217|Ensembl:ENSG00000112280|Vega:OTTHUMG00000014988 +1298 COL9A2 MIM:120260|HGNC:HGNC:2218|Ensembl:ENSG00000049089|Vega:OTTHUMG00000005761 +1299 COL9A3 MIM:120270|HGNC:HGNC:2219|Ensembl:ENSG00000092758|Vega:OTTHUMG00000032938 +1300 COL10A1 MIM:120110|HGNC:HGNC:2185|Ensembl:ENSG00000123500|Vega:OTTHUMG00000015426 +1301 COL11A1 MIM:120280|HGNC:HGNC:2186|Ensembl:ENSG00000060718|Vega:OTTHUMG00000010872 +1302 COL11A2 MIM:120290|HGNC:HGNC:2187|Ensembl:ENSG00000204248|Vega:OTTHUMG00000031036 +1303 COL12A1 MIM:120320|HGNC:HGNC:2188|Ensembl:ENSG00000111799|Vega:OTTHUMG00000015051 +1305 COL13A1 MIM:120350|HGNC:HGNC:2190|Ensembl:ENSG00000197467|Vega:OTTHUMG00000018394 +1306 COL15A1 MIM:120325|HGNC:HGNC:2192|Ensembl:ENSG00000204291|Vega:OTTHUMG00000020351 +1307 COL16A1 MIM:120326|HGNC:HGNC:2193|Ensembl:ENSG00000084636|Vega:OTTHUMG00000003883 +1308 COL17A1 MIM:113811|HGNC:HGNC:2194|Ensembl:ENSG00000065618|Vega:OTTHUMG00000018998 +1310 COL19A1 MIM:120165|HGNC:HGNC:2196|Ensembl:ENSG00000082293|Vega:OTTHUMG00000014987 +1311 COMP MIM:600310|HGNC:HGNC:2227|Ensembl:ENSG00000105664|Vega:OTTHUMG00000169318 +1312 COMT MIM:116790|HGNC:HGNC:2228|Ensembl:ENSG00000093010|Vega:OTTHUMG00000150529 +1314 COPA MIM:601924|HGNC:HGNC:2230|Ensembl:ENSG00000122218|Vega:OTTHUMG00000033111 +1315 COPB1 MIM:600959|HGNC:HGNC:2231|Ensembl:ENSG00000129083|Vega:OTTHUMG00000165824 +1316 KLF6 MIM:602053|HGNC:HGNC:2235|Ensembl:ENSG00000067082|Vega:OTTHUMG00000017567 +1317 SLC31A1 MIM:603085|HGNC:HGNC:11016|Ensembl:ENSG00000136868|Vega:OTTHUMG00000020519 +1318 SLC31A2 MIM:603088|HGNC:HGNC:11017|Ensembl:ENSG00000136867|Vega:OTTHUMG00000021037 +1319 CORD1 MIM:600624|HGNC:HGNC:2245 +1321 CORD4 HGNC:HGNC:2247 +1325 CORT MIM:602784|HGNC:HGNC:2257|Ensembl:ENSG00000241563|Vega:OTTHUMG00000001906 +1326 MAP3K8 MIM:191195|HGNC:HGNC:6860|Ensembl:ENSG00000107968|Vega:OTTHUMG00000017889 +1327 COX4I1 MIM:123864|HGNC:HGNC:2265|Ensembl:ENSG00000131143|Vega:OTTHUMG00000137649 +1329 COX5B MIM:123866|HGNC:HGNC:2269|Ensembl:ENSG00000135940|Vega:OTTHUMG00000130548 +1330 COX5BP1 HGNC:HGNC:2270 +1331 COX5BP2 HGNC:HGNC:2271 +1332 COX5BP3 HGNC:HGNC:2272 +1333 COX5BP4 HGNC:HGNC:2273 +1336 COX5BP7 HGNC:HGNC:2276 +1337 COX6A1 MIM:602072|HGNC:HGNC:2277|Ensembl:ENSG00000111775|Vega:OTTHUMG00000047791 +1338 COX6A1P1 HGNC:HGNC:2278 +1339 COX6A2 MIM:602009|HGNC:HGNC:2279|Ensembl:ENSG00000156885|Vega:OTTHUMG00000132463 +1340 COX6B1 MIM:124089|HGNC:HGNC:2280|Ensembl:ENSG00000126267|Vega:OTTHUMG00000048112 +1342 COX6B1P2 HGNC:HGNC:2282 +1343 COX6B1P3 HGNC:HGNC:2283 +1345 COX6C MIM:124090|HGNC:HGNC:2285|Ensembl:ENSG00000164919|Vega:OTTHUMG00000164703 +1346 COX7A1 MIM:123995|HGNC:HGNC:2287|Ensembl:ENSG00000161281|Vega:OTTHUMG00000048144 +1347 COX7A2 MIM:123996|HGNC:HGNC:2288|Ensembl:ENSG00000112695|Vega:OTTHUMG00000015049 +1348 COX7A2P2 MIM:123997|HGNC:HGNC:2290 +1349 COX7B MIM:300885|HGNC:HGNC:2291|Ensembl:ENSG00000131174|Vega:OTTHUMG00000022718 +1350 COX7C MIM:603774|HGNC:HGNC:2292|Ensembl:ENSG00000127184|Vega:OTTHUMG00000119049 +1351 COX8A MIM:123870|HGNC:HGNC:2294|Ensembl:ENSG00000176340|Vega:OTTHUMG00000167785 +1352 COX10 MIM:602125|HGNC:HGNC:2260|Ensembl:ENSG00000006695|Vega:OTTHUMG00000058814 +1353 COX11 MIM:603648|HGNC:HGNC:2261|Ensembl:ENSG00000141198|Ensembl:ENSG00000166260|Vega:OTTHUMG00000177838 +1355 COX15 MIM:603646|HGNC:HGNC:2263|Ensembl:ENSG00000014919|Vega:OTTHUMG00000018893 +1356 CP MIM:117700|HGNC:HGNC:2295|Ensembl:ENSG00000047457|Vega:OTTHUMG00000159563 +1357 CPA1 MIM:114850|HGNC:HGNC:2296|Ensembl:ENSG00000091704|Vega:OTTHUMG00000157826 +1358 CPA2 MIM:600688|HGNC:HGNC:2297|Ensembl:ENSG00000158516|Vega:OTTHUMG00000157019 +1359 CPA3 MIM:114851|HGNC:HGNC:2298|Ensembl:ENSG00000163751|Vega:OTTHUMG00000159526 +1360 CPB1 MIM:114852|HGNC:HGNC:2299|Ensembl:ENSG00000153002|Vega:OTTHUMG00000159520 +1361 CPB2 MIM:603101|HGNC:HGNC:2300|Ensembl:ENSG00000080618|Vega:OTTHUMG00000016867 +1362 CPD MIM:603102|HGNC:HGNC:2301|Ensembl:ENSG00000108582|Vega:OTTHUMG00000132797 +1363 CPE MIM:114855|HGNC:HGNC:2303|Ensembl:ENSG00000109472|Vega:OTTHUMG00000150252 +1364 CLDN4 MIM:602909|HGNC:HGNC:2046|Ensembl:ENSG00000189143|Vega:OTTHUMG00000023425 +1365 CLDN3 MIM:602910|HGNC:HGNC:2045|Ensembl:ENSG00000165215|Vega:OTTHUMG00000023424 +1366 CLDN7 MIM:609131|HGNC:HGNC:2049|Ensembl:ENSG00000181885|Vega:OTTHUMG00000178005 +1368 CPM MIM:114860|HGNC:HGNC:2311|Ensembl:ENSG00000135678|Vega:OTTHUMG00000169300 +1369 CPN1 MIM:603103|HGNC:HGNC:2312|Ensembl:ENSG00000120054|Vega:OTTHUMG00000018896 +1370 CPN2 MIM:603104|HGNC:HGNC:2313|Ensembl:ENSG00000178772|Vega:OTTHUMG00000156047 +1371 CPOX MIM:612732|HGNC:HGNC:2321|Ensembl:ENSG00000080819|Vega:OTTHUMG00000160016 +1373 CPS1 MIM:608307|HGNC:HGNC:2323|Ensembl:ENSG00000021826|Vega:OTTHUMG00000132994 +1374 CPT1A MIM:600528|HGNC:HGNC:2328|Ensembl:ENSG00000110090|Vega:OTTHUMG00000167892 +1375 CPT1B MIM:601987|HGNC:HGNC:2329|Ensembl:ENSG00000205560|Vega:OTTHUMG00000137390 +1376 CPT2 MIM:600650|HGNC:HGNC:2330|Ensembl:ENSG00000157184|Vega:OTTHUMG00000008942 +1378 CR1 MIM:120620|HGNC:HGNC:2334|Ensembl:ENSG00000203710|Vega:OTTHUMG00000036311 +1379 CR1L MIM:605886|HGNC:HGNC:2335|Ensembl:ENSG00000197721|Vega:OTTHUMG00000036354 +1380 CR2 MIM:120650|HGNC:HGNC:2336|Ensembl:ENSG00000117322|Vega:OTTHUMG00000036307 +1381 CRABP1 MIM:180230|HGNC:HGNC:2338|Ensembl:ENSG00000166426|Vega:OTTHUMG00000143862 +1382 CRABP2 MIM:180231|HGNC:HGNC:2339|Ensembl:ENSG00000143320|Vega:OTTHUMG00000041300 +1384 CRAT MIM:600184|HGNC:HGNC:2342|Ensembl:ENSG00000095321|Vega:OTTHUMG00000147343 +1385 CREB1 MIM:123810|HGNC:HGNC:2345|Ensembl:ENSG00000118260|Vega:OTTHUMG00000132936 +1386 ATF2 MIM:123811|HGNC:HGNC:784|Ensembl:ENSG00000115966|Vega:OTTHUMG00000132424 +1387 CREBBP MIM:600140|HGNC:HGNC:2348|Ensembl:ENSG00000005339|Vega:OTTHUMG00000129431 +1388 ATF6B MIM:600984|HGNC:HGNC:2349|Ensembl:ENSG00000213676|Vega:OTTHUMG00000031296 +1389 CREBL2 MIM:603476|HGNC:HGNC:2350|Ensembl:ENSG00000111269|Vega:OTTHUMG00000168704 +1390 CREM MIM:123812|HGNC:HGNC:2352|Ensembl:ENSG00000095794|Vega:OTTHUMG00000017953 +1392 CRH MIM:122560|HGNC:HGNC:2355|Ensembl:ENSG00000147571|Vega:OTTHUMG00000164474 +1393 CRHBP MIM:122559|HGNC:HGNC:2356|Ensembl:ENSG00000145708|Vega:OTTHUMG00000102133 +1394 CRHR1 MIM:122561|HGNC:HGNC:2357|Ensembl:ENSG00000120088|Vega:OTTHUMG00000178271 +1395 CRHR2 MIM:602034|HGNC:HGNC:2358|Ensembl:ENSG00000106113|Vega:OTTHUMG00000023218 +1396 CRIP1 MIM:123875|HGNC:HGNC:2360|Ensembl:ENSG00000213145|Ensembl:ENSG00000257341|Vega:OTTHUMG00000029908|Vega:OTTHUMG00000029910 +1397 CRIP2 MIM:601183|HGNC:HGNC:2361|Ensembl:ENSG00000182809|Vega:OTTHUMG00000029906 +1398 CRK MIM:164762|HGNC:HGNC:2362|Ensembl:ENSG00000167193|Vega:OTTHUMG00000090317 +1399 CRKL MIM:602007|HGNC:HGNC:2363|Ensembl:ENSG00000099942|Vega:OTTHUMG00000150807 +1400 CRMP1 MIM:602462|HGNC:HGNC:2365|Ensembl:ENSG00000072832|Vega:OTTHUMG00000125489 +1401 CRP MIM:123260|HGNC:HGNC:2367|Ensembl:ENSG00000132693|Vega:OTTHUMG00000035344 +1404 HAPLN1 MIM:115435|HGNC:HGNC:2380|Ensembl:ENSG00000145681|Vega:OTTHUMG00000119045 +1406 CRX MIM:602225|HGNC:HGNC:2383|Ensembl:ENSG00000105392|Vega:OTTHUMG00000170610 +1407 CRY1 MIM:601933|HGNC:HGNC:2384|Ensembl:ENSG00000008405|Vega:OTTHUMG00000170005 +1408 CRY2 MIM:603732|HGNC:HGNC:2385|Ensembl:ENSG00000121671|Vega:OTTHUMG00000153225 +1409 CRYAA MIM:123580|HGNC:HGNC:2388|Ensembl:ENSG00000160202|Vega:OTTHUMG00000086842 +1410 CRYAB MIM:123590|HGNC:HGNC:2389|Ensembl:ENSG00000109846|Vega:OTTHUMG00000166885 +1411 CRYBA1 MIM:123610|HGNC:HGNC:2394|Ensembl:ENSG00000108255|Vega:OTTHUMG00000132729 +1412 CRYBA2 MIM:600836|HGNC:HGNC:2395|Ensembl:ENSG00000163499|Vega:OTTHUMG00000133084 +1413 CRYBA4 MIM:123631|HGNC:HGNC:2396|Ensembl:ENSG00000196431|Vega:OTTHUMG00000150983 +1414 CRYBB1 MIM:600929|HGNC:HGNC:2397|Ensembl:ENSG00000100122|Vega:OTTHUMG00000150980 +1415 CRYBB2 MIM:123620|HGNC:HGNC:2398|Ensembl:ENSG00000244752|Vega:OTTHUMG00000150905 +1416 CRYBB2P1 HGNC:HGNC:2399|Ensembl:ENSG00000100058 +1417 CRYBB3 MIM:123630|HGNC:HGNC:2400|Ensembl:ENSG00000100053|Vega:OTTHUMG00000150869 +1418 CRYGA MIM:123660|HGNC:HGNC:2408|Ensembl:ENSG00000168582|Vega:OTTHUMG00000154796 +1419 CRYGB MIM:123670|HGNC:HGNC:2409|Ensembl:ENSG00000182187|Vega:OTTHUMG00000132941 +1420 CRYGC MIM:123680|HGNC:HGNC:2410|Ensembl:ENSG00000163254|Vega:OTTHUMG00000132942 +1421 CRYGD MIM:123690|HGNC:HGNC:2411|Ensembl:ENSG00000118231|Vega:OTTHUMG00000132944 +1423 CRYGFP HGNC:HGNC:2413 +1424 CRYGGP HGNC:HGNC:2414 +1427 CRYGS MIM:123730|HGNC:HGNC:2417|Ensembl:ENSG00000213139|Vega:OTTHUMG00000156615 +1428 CRYM MIM:123740|HGNC:HGNC:2418|Ensembl:ENSG00000103316|Vega:OTTHUMG00000090707 +1429 CRYZ MIM:123691|HGNC:HGNC:2419|Ensembl:ENSG00000116791|Vega:OTTHUMG00000009620 +1430 CRYZP1 HGNC:HGNC:2421 +1431 CS MIM:118950|HGNC:HGNC:2422|Ensembl:ENSG00000062485|Vega:OTTHUMG00000170344 +1432 MAPK14 MIM:600289|HGNC:HGNC:6876|Ensembl:ENSG00000112062|Vega:OTTHUMG00000159806 +1434 CSE1L MIM:601342|HGNC:HGNC:2431|Ensembl:ENSG00000124207|Vega:OTTHUMG00000033046 +1435 CSF1 MIM:120420|HGNC:HGNC:2432|Ensembl:ENSG00000184371|Vega:OTTHUMG00000011646 +1436 CSF1R MIM:164770|HGNC:HGNC:2433|Ensembl:ENSG00000182578|Vega:OTTHUMG00000130050 +1437 CSF2 MIM:138960|HGNC:HGNC:2434|Ensembl:ENSG00000164400|Vega:OTTHUMG00000059637 +1438 CSF2RA MIM:306250|MIM:425000|HGNC:HGNC:2435|Ensembl:ENSG00000198223|Vega:OTTHUMG00000012533 +1439 CSF2RB MIM:138981|HGNC:HGNC:2436|Ensembl:ENSG00000100368|Vega:OTTHUMG00000150546 +1440 CSF3 MIM:138970|HGNC:HGNC:2438|Ensembl:ENSG00000108342|Vega:OTTHUMG00000133247 +1441 CSF3R MIM:138971|HGNC:HGNC:2439|Ensembl:ENSG00000119535|Vega:OTTHUMG00000008010 +1442 CSH1 MIM:150200|HGNC:HGNC:2440|Ensembl:ENSG00000136488|Vega:OTTHUMG00000171947 +1443 CSH2 MIM:118820|HGNC:HGNC:2441|Ensembl:ENSG00000213218|Vega:OTTHUMG00000172283 +1444 CSHL1 MIM:603515|HGNC:HGNC:2442|Ensembl:ENSG00000204414|Vega:OTTHUMG00000172287 +1445 CSK MIM:124095|HGNC:HGNC:2444|Ensembl:ENSG00000103653|Vega:OTTHUMG00000142814 +1446 CSN1S1 MIM:115450|HGNC:HGNC:2445|Ensembl:ENSG00000126545|Vega:OTTHUMG00000160843 +1447 CSN2 MIM:115460|HGNC:HGNC:2447|Ensembl:ENSG00000135222|Vega:OTTHUMG00000129409 +1448 CSN3 MIM:601695|HGNC:HGNC:2446|Ensembl:ENSG00000171209|Vega:OTTHUMG00000129399 +1452 CSNK1A1 MIM:600505|HGNC:HGNC:2451|Ensembl:ENSG00000113712|Vega:OTTHUMG00000163463 +1453 CSNK1D MIM:600864|HGNC:HGNC:2452|Ensembl:ENSG00000141551|Vega:OTTHUMG00000178601 +1454 CSNK1E MIM:600863|HGNC:HGNC:2453|Ensembl:ENSG00000213923|Vega:OTTHUMG00000151135 +1455 CSNK1G2 MIM:602214|HGNC:HGNC:2455|Ensembl:ENSG00000133275|Vega:OTTHUMG00000180016 +1456 CSNK1G3 MIM:604253|HGNC:HGNC:2456|Ensembl:ENSG00000151292|Vega:OTTHUMG00000128923 +1457 CSNK2A1 MIM:115440|HGNC:HGNC:2457|Ensembl:ENSG00000101266|Vega:OTTHUMG00000031636 +1459 CSNK2A2 MIM:115442|HGNC:HGNC:2459|Ensembl:ENSG00000070770|Vega:OTTHUMG00000133488 +1460 CSNK2B MIM:115441|HGNC:HGNC:2460|Ensembl:ENSG00000204435|Vega:OTTHUMG00000177888 +1462 VCAN MIM:118661|HGNC:HGNC:2464|Ensembl:ENSG00000038427|Vega:OTTHUMG00000131321 +1463 NCAN MIM:600826|HGNC:HGNC:2465|Ensembl:ENSG00000130287|Vega:OTTHUMG00000182218 +1464 CSPG4 MIM:601172|HGNC:HGNC:2466|Ensembl:ENSG00000173546|Vega:OTTHUMG00000142836 +1465 CSRP1 MIM:123876|HGNC:HGNC:2469|Ensembl:ENSG00000159176|Vega:OTTHUMG00000035773 +1466 CSRP2 MIM:601871|HGNC:HGNC:2470|Ensembl:ENSG00000175183|Vega:OTTHUMG00000169919 +1467 CSRP2P1 HGNC:HGNC:2471 +1468 SLC25A10 MIM:606794|HGNC:HGNC:10980|Ensembl:ENSG00000183048|Vega:OTTHUMG00000178173 +1469 CST1 MIM:123855|HGNC:HGNC:2473|Ensembl:ENSG00000170373|Vega:OTTHUMG00000032085 +1470 CST2 MIM:123856|HGNC:HGNC:2474|Ensembl:ENSG00000170369|Vega:OTTHUMG00000032086 +1471 CST3 MIM:604312|HGNC:HGNC:2475|Ensembl:ENSG00000101439|Vega:OTTHUMG00000032080 +1472 CST4 MIM:123857|HGNC:HGNC:2476|Ensembl:ENSG00000101441|Vega:OTTHUMG00000032083 +1473 CST5 MIM:123858|HGNC:HGNC:2477|Ensembl:ENSG00000170367|Vega:OTTHUMG00000032089 +1474 CST6 MIM:601891|HGNC:HGNC:2478|Ensembl:ENSG00000175315|Vega:OTTHUMG00000166750 +1475 CSTA MIM:184600|HGNC:HGNC:2481|Ensembl:ENSG00000121552|Vega:OTTHUMG00000159488 +1476 CSTB MIM:601145|HGNC:HGNC:2482|Ensembl:ENSG00000160213|Vega:OTTHUMG00000086886 +1477 CSTF1 MIM:600369|HGNC:HGNC:2483|Ensembl:ENSG00000101138|Vega:OTTHUMG00000032791 +1478 CSTF2 MIM:300907|HGNC:HGNC:2484|Ensembl:ENSG00000101811|Vega:OTTHUMG00000022709 +1479 CSTF3 MIM:600367|HGNC:HGNC:2485|Ensembl:ENSG00000176102|Vega:OTTHUMG00000166268 +1480 CSTP1 HGNC:HGNC:2486 +1481 CSTP2 HGNC:HGNC:2487 +1482 NKX2-5 MIM:600584|HGNC:HGNC:2488|Ensembl:ENSG00000183072|Vega:OTTHUMG00000130522 +1483 CTAA1 MIM:115650|HGNC:HGNC:2489 +1484 CTAA2 MIM:601202|HGNC:HGNC:2490 +1485 CTAG1B MIM:300156|HGNC:HGNC:2491|Ensembl:ENSG00000184033|Vega:OTTHUMG00000024232 +1486 CTBS MIM:600873|HGNC:HGNC:2496|Ensembl:ENSG00000117151|Vega:OTTHUMG00000009922 +1487 CTBP1 MIM:602618|HGNC:HGNC:2494|Ensembl:ENSG00000159692|Vega:OTTHUMG00000089259 +1488 CTBP2 MIM:602619|HGNC:HGNC:2495|Ensembl:ENSG00000175029|Vega:OTTHUMG00000019224 +1489 CTF1 MIM:600435|HGNC:HGNC:2499|Ensembl:ENSG00000150281|Vega:OTTHUMG00000132413 +1490 CTGF MIM:121009|HGNC:HGNC:2500|Ensembl:ENSG00000118523|Vega:OTTHUMG00000015573 +1491 CTH MIM:607657|HGNC:HGNC:2501|Ensembl:ENSG00000116761|Vega:OTTHUMG00000009352 +1493 CTLA4 MIM:123890|HGNC:HGNC:2505|Ensembl:ENSG00000163599|Vega:OTTHUMG00000132877 +1495 CTNNA1 MIM:116805|HGNC:HGNC:2509|Ensembl:ENSG00000044115|Vega:OTTHUMG00000163502 +1496 CTNNA2 MIM:114025|HGNC:HGNC:2510|Ensembl:ENSG00000066032|Vega:OTTHUMG00000152903 +1497 CTNS MIM:606272|HGNC:HGNC:2518|Ensembl:ENSG00000040531|Vega:OTTHUMG00000090693 +1498 CTNNA1P1 HGNC:HGNC:2513 +1499 CTNNB1 MIM:116806|HGNC:HGNC:2514|Ensembl:ENSG00000168036|Vega:OTTHUMG00000131393 +1500 CTNND1 MIM:601045|HGNC:HGNC:2515|Ensembl:ENSG00000198561|Vega:OTTHUMG00000167272 +1501 CTNND2 MIM:604275|HGNC:HGNC:2516|Ensembl:ENSG00000169862|Vega:OTTHUMG00000090511 +1503 CTPS1 MIM:123860|HGNC:HGNC:2519|Ensembl:ENSG00000171793|Vega:OTTHUMG00000005712 +1504 CTRB1 MIM:118890|HGNC:HGNC:2521|Ensembl:ENSG00000168925|Vega:OTTHUMG00000159272 +1506 CTRL MIM:118888|HGNC:HGNC:2524|Ensembl:ENSG00000141086|Vega:OTTHUMG00000137552 +1508 CTSB MIM:116810|HGNC:HGNC:2527|Ensembl:ENSG00000164733|Vega:OTTHUMG00000090799 +1509 CTSD MIM:116840|HGNC:HGNC:2529|Ensembl:ENSG00000117984|Vega:OTTHUMG00000044760 +1510 CTSE MIM:116890|HGNC:HGNC:2530|Ensembl:ENSG00000196188|Vega:OTTHUMG00000036121 +1511 CTSG MIM:116830|HGNC:HGNC:2532|Ensembl:ENSG00000100448|Vega:OTTHUMG00000140182 +1512 CTSH MIM:116820|HGNC:HGNC:2535|Ensembl:ENSG00000103811|Vega:OTTHUMG00000144171 +1513 CTSK MIM:601105|HGNC:HGNC:2536|Ensembl:ENSG00000143387|Vega:OTTHUMG00000035008 +1514 CTSL MIM:116880|HGNC:HGNC:2537|Ensembl:ENSG00000135047|Vega:OTTHUMG00000020149 +1515 CTSV MIM:603308|HGNC:HGNC:2538|Ensembl:ENSG00000136943|Vega:OTTHUMG00000020314 +1517 CTSLP2 HGNC:HGNC:2540 +1518 CTSLP8 HGNC:HGNC:39084 +1519 CTSO MIM:600550|HGNC:HGNC:2542|Ensembl:ENSG00000256043|Vega:OTTHUMG00000161942 +1520 CTSS MIM:116845|HGNC:HGNC:2545|Ensembl:ENSG00000163131|Vega:OTTHUMG00000035010 +1521 CTSW MIM:602364|HGNC:HGNC:2546|Ensembl:ENSG00000172543|Vega:OTTHUMG00000166663 +1522 CTSZ MIM:603169|HGNC:HGNC:2547|Ensembl:ENSG00000101160|Vega:OTTHUMG00000032858 +1523 CUX1 MIM:116896|HGNC:HGNC:2557|Ensembl:ENSG00000257923|Vega:OTTHUMG00000157129 +1524 CX3CR1 MIM:601470|HGNC:HGNC:2558|Ensembl:ENSG00000168329|Vega:OTTHUMG00000156249 +1525 CXADR MIM:602621|HGNC:HGNC:2559|Ensembl:ENSG00000154639|Vega:OTTHUMG00000074508 +1526 CXB3S MIM:120050|HGNC:HGNC:2560 +1527 TEX28 MIM:300092|HGNC:HGNC:2563|Ensembl:ENSG00000278057|Vega:OTTHUMG00000022654 +1528 CYB5A MIM:613218|HGNC:HGNC:2570|Ensembl:ENSG00000166347|Vega:OTTHUMG00000132843 +1531 CYB5AP3 HGNC:HGNC:2574 +1532 CYB5AP4 HGNC:HGNC:2575 +1534 CYB561 MIM:600019|HGNC:HGNC:2571|Ensembl:ENSG00000008283|Vega:OTTHUMG00000179116 +1535 CYBA MIM:608508|HGNC:HGNC:2577|Ensembl:ENSG00000051523|Vega:OTTHUMG00000173320 +1536 CYBB MIM:300481|HGNC:HGNC:2578|Ensembl:ENSG00000165168|Vega:OTTHUMG00000033175 +1537 CYC1 MIM:123980|HGNC:HGNC:2579|Ensembl:ENSG00000179091|Vega:OTTHUMG00000165242 +1538 CYLC1 MIM:300768|HGNC:HGNC:2582|Ensembl:ENSG00000183035|Vega:OTTHUMG00000021922 +1539 CYLC2 MIM:604035|HGNC:HGNC:2583|Ensembl:ENSG00000155833|Vega:OTTHUMG00000020396 +1540 CYLD MIM:605018|HGNC:HGNC:2584|Ensembl:ENSG00000083799|Vega:OTTHUMG00000173404 +1541 CYMD MIM:153880|HGNC:HGNC:2587 +1543 CYP1A1 MIM:108330|HGNC:HGNC:2595|Ensembl:ENSG00000140465|Vega:OTTHUMG00000142812 +1544 CYP1A2 MIM:124060|HGNC:HGNC:2596|Ensembl:ENSG00000140505|Vega:OTTHUMG00000172901 +1545 CYP1B1 MIM:601771|HGNC:HGNC:2597|Ensembl:ENSG00000138061|Vega:OTTHUMG00000100970 +1548 CYP2A6 MIM:122720|HGNC:HGNC:2610|Ensembl:ENSG00000255974|Vega:OTTHUMG00000182713 +1549 CYP2A7 MIM:608054|HGNC:HGNC:2611|Ensembl:ENSG00000198077|Vega:OTTHUMG00000182715 +1550 CYP2A7P1 HGNC:HGNC:2612 +1551 CYP3A7 MIM:605340|HGNC:HGNC:2640|Ensembl:ENSG00000160870|Vega:OTTHUMG00000156726 +1553 CYP2A13 MIM:608055|HGNC:HGNC:2608|Ensembl:ENSG00000197838|Vega:OTTHUMG00000182762 +1555 CYP2B6 MIM:123930|HGNC:HGNC:2615|Ensembl:ENSG00000197408|Vega:OTTHUMG00000182714 +1556 CYP2B7P HGNC:HGNC:2616|Ensembl:ENSG00000256612 +1557 CYP2C19 MIM:124020|HGNC:HGNC:2621|Ensembl:ENSG00000165841|Vega:OTTHUMG00000018799 +1558 CYP2C8 MIM:601129|HGNC:HGNC:2622|Ensembl:ENSG00000138115|Vega:OTTHUMG00000018804 +1559 CYP2C9 MIM:601130|HGNC:HGNC:2623|Ensembl:ENSG00000138109|Vega:OTTHUMG00000018805 +1562 CYP2C18 MIM:601131|HGNC:HGNC:2620|Ensembl:ENSG00000108242|Vega:OTTHUMG00000018796 +1564 CYP2D7 HGNC:HGNC:2624|Ensembl:ENSG00000205702|Vega:OTTHUMG00000030222 +1565 CYP2D6 MIM:124030|HGNC:HGNC:2625|Ensembl:ENSG00000100197|Vega:OTTHUMG00000150918 +1566 CYP2D7BP - +1568 CYP2D8P HGNC:HGNC:2628 +1571 CYP2E1 MIM:124040|HGNC:HGNC:2631|Ensembl:ENSG00000130649|Vega:OTTHUMG00000019322 +1572 CYP2F1 MIM:124070|HGNC:HGNC:2632|Ensembl:ENSG00000197446|Vega:OTTHUMG00000167412 +1573 CYP2J2 MIM:601258|HGNC:HGNC:2634|Ensembl:ENSG00000134716|Vega:OTTHUMG00000008991 +1576 CYP3A4 MIM:124010|HGNC:HGNC:2637|Ensembl:ENSG00000160868|Vega:OTTHUMG00000156651 +1577 CYP3A5 MIM:605325|HGNC:HGNC:2638|Ensembl:ENSG00000106258|Vega:OTTHUMG00000156724 +1578 CYP3A51P HGNC:HGNC:42418 +1579 CYP4A11 MIM:601310|HGNC:HGNC:2642|Ensembl:ENSG00000187048|Vega:OTTHUMG00000008020 +1580 CYP4B1 MIM:124075|HGNC:HGNC:2644|Ensembl:ENSG00000142973|Vega:OTTHUMG00000007984 +1581 CYP7A1 MIM:118455|HGNC:HGNC:2651|Ensembl:ENSG00000167910|Vega:OTTHUMG00000164301 +1582 CYP8B1 MIM:602172|HGNC:HGNC:2653|Ensembl:ENSG00000180432|Vega:OTTHUMG00000133047 +1583 CYP11A1 MIM:118485|HGNC:HGNC:2590|Ensembl:ENSG00000140459|Vega:OTTHUMG00000150716 +1584 CYP11B1 MIM:610613|HGNC:HGNC:2591|Ensembl:ENSG00000160882|Vega:OTTHUMG00000164637 +1585 CYP11B2 MIM:124080|HGNC:HGNC:2592|Ensembl:ENSG00000179142|Vega:OTTHUMG00000160254 +1586 CYP17A1 MIM:609300|HGNC:HGNC:2593|Ensembl:ENSG00000148795|Vega:OTTHUMG00000018969 +1587 ADAM3A HGNC:HGNC:209|Ensembl:ENSG00000197475 +1588 CYP19A1 MIM:107910|HGNC:HGNC:2594|Ensembl:ENSG00000137869|Vega:OTTHUMG00000131747 +1589 CYP21A2 MIM:613815|HGNC:HGNC:2600|Ensembl:ENSG00000231852|Vega:OTTHUMG00000031069 +1590 CYP21A1P HGNC:HGNC:2599|Ensembl:ENSG00000204338 +1591 CYP24A1 MIM:126065|HGNC:HGNC:2602|Ensembl:ENSG00000019186|Vega:OTTHUMG00000032773 +1592 CYP26A1 MIM:602239|HGNC:HGNC:2603|Ensembl:ENSG00000095596|Vega:OTTHUMG00000018765 +1593 CYP27A1 MIM:606530|HGNC:HGNC:2605|Ensembl:ENSG00000135929|Vega:OTTHUMG00000048238 +1594 CYP27B1 MIM:609506|HGNC:HGNC:2606|Ensembl:ENSG00000111012|Vega:OTTHUMG00000170457 +1595 CYP51A1 MIM:601637|HGNC:HGNC:2649|Ensembl:ENSG00000001630|Vega:OTTHUMG00000131131 +1596 ADAM3B HGNC:HGNC:210 +1600 DAB1 MIM:603448|HGNC:HGNC:2661|Ensembl:ENSG00000173406|Vega:OTTHUMG00000008391 +1601 DAB2 MIM:601236|HGNC:HGNC:2662|Ensembl:ENSG00000153071|Vega:OTTHUMG00000162043 +1602 DACH1 MIM:603803|HGNC:HGNC:2663|Ensembl:ENSG00000276644|Vega:OTTHUMG00000017063 +1603 DAD1 MIM:600243|HGNC:HGNC:2664|Ensembl:ENSG00000129562|Vega:OTTHUMG00000028685 +1604 CD55 MIM:125240|HGNC:HGNC:2665|Ensembl:ENSG00000196352|Vega:OTTHUMG00000036255 +1605 DAG1 MIM:128239|HGNC:HGNC:2666|Ensembl:ENSG00000173402|Vega:OTTHUMG00000156869 +1606 DGKA MIM:125855|HGNC:HGNC:2849|Ensembl:ENSG00000065357|Vega:OTTHUMG00000170109 +1607 DGKB MIM:604070|HGNC:HGNC:2850|Ensembl:ENSG00000136267|Vega:OTTHUMG00000152477 +1608 DGKG MIM:601854|HGNC:HGNC:2853|Ensembl:ENSG00000058866|Vega:OTTHUMG00000156617 +1609 DGKQ MIM:601207|HGNC:HGNC:2856|Ensembl:ENSG00000145214|Vega:OTTHUMG00000088629 +1610 DAO MIM:124050|HGNC:HGNC:2671|Ensembl:ENSG00000110887|Vega:OTTHUMG00000169360 +1611 DAP MIM:600954|HGNC:HGNC:2672|Ensembl:ENSG00000112977|Vega:OTTHUMG00000131041 +1612 DAPK1 MIM:600831|HGNC:HGNC:2674|Ensembl:ENSG00000196730|Vega:OTTHUMG00000020150 +1613 DAPK3 MIM:603289|HGNC:HGNC:2676|Ensembl:ENSG00000167657|Vega:OTTHUMG00000181825 +1615 DARS MIM:603084|HGNC:HGNC:2678|Ensembl:ENSG00000115866|Vega:OTTHUMG00000131741 +1616 DAXX MIM:603186|HGNC:HGNC:2681|Ensembl:ENSG00000204209|Vega:OTTHUMG00000031203 +1617 DAZ1 MIM:400003|HGNC:HGNC:2682|Ensembl:ENSG00000188120|Vega:OTTHUMG00000044053 +1618 DAZL MIM:601486|HGNC:HGNC:2685|Ensembl:ENSG00000092345|Vega:OTTHUMG00000157050 +1620 BRINP1 MIM:602865|HGNC:HGNC:2687|Ensembl:ENSG00000078725|Vega:OTTHUMG00000021020 +1621 DBH MIM:609312|HGNC:HGNC:2689|Ensembl:ENSG00000123454|Vega:OTTHUMG00000020878 +1622 DBI MIM:125950|HGNC:HGNC:2690|Ensembl:ENSG00000155368|Vega:OTTHUMG00000131403 +1623 DBIP2 HGNC:HGNC:2691 +1624 DBIP1 HGNC:HGNC:2692 +1627 DBN1 MIM:126660|HGNC:HGNC:2695|Ensembl:ENSG00000113758|Vega:OTTHUMG00000130856 +1628 DBP MIM:124097|HGNC:HGNC:2697|Ensembl:ENSG00000105516|Vega:OTTHUMG00000183319 +1629 DBT MIM:248610|HGNC:HGNC:2698|Ensembl:ENSG00000137992|Vega:OTTHUMG00000010921 +1630 DCC MIM:120470|HGNC:HGNC:2701|Ensembl:ENSG00000187323|Vega:OTTHUMG00000132698 +1632 ECI1 MIM:600305|HGNC:HGNC:2703|Ensembl:ENSG00000167969|Vega:OTTHUMG00000128830 +1633 DCK MIM:125450|HGNC:HGNC:2704|Ensembl:ENSG00000156136|Vega:OTTHUMG00000129908 +1634 DCN MIM:125255|HGNC:HGNC:2705|Ensembl:ENSG00000011465|Vega:OTTHUMG00000169998 +1635 DCTD MIM:607638|HGNC:HGNC:2710|Ensembl:ENSG00000129187|Vega:OTTHUMG00000160685 +1636 ACE MIM:106180|HGNC:HGNC:2707|Ensembl:ENSG00000159640|Ensembl:ENSG00000264813|Vega:OTTHUMG00000154927|Vega:OTTHUMG00000178900 +1637 DCR MIM:190685|HGNC:HGNC:2708 +1638 DCT MIM:191275|HGNC:HGNC:2709|Ensembl:ENSG00000080166|Vega:OTTHUMG00000017206 +1639 DCTN1 MIM:601143|HGNC:HGNC:2711|Ensembl:ENSG00000204843|Vega:OTTHUMG00000129963 +1641 DCX MIM:300121|HGNC:HGNC:2714|Ensembl:ENSG00000077279|Vega:OTTHUMG00000022204 +1642 DDB1 MIM:600045|HGNC:HGNC:2717|Ensembl:ENSG00000167986|Vega:OTTHUMG00000168209 +1643 DDB2 MIM:600811|HGNC:HGNC:2718|Ensembl:ENSG00000134574|Vega:OTTHUMG00000187453 +1644 DDC MIM:107930|HGNC:HGNC:2719|Ensembl:ENSG00000132437|Vega:OTTHUMG00000023353 +1645 AKR1C1 MIM:600449|HGNC:HGNC:384|Ensembl:ENSG00000187134|Vega:OTTHUMG00000017580 +1646 AKR1C2 MIM:600450|HGNC:HGNC:385|Ensembl:ENSG00000151632|Vega:OTTHUMG00000017584 +1647 GADD45A MIM:126335|HGNC:HGNC:4095|Ensembl:ENSG00000116717|Vega:OTTHUMG00000009374 +1648 GADD45AP1 HGNC:HGNC:2725 +1649 DDIT3 MIM:126337|HGNC:HGNC:2726|Ensembl:ENSG00000175197|Vega:OTTHUMG00000170046 +1650 DDOST MIM:602202|HGNC:HGNC:2728|Ensembl:ENSG00000244038|Vega:OTTHUMG00000002844 +1652 DDT MIM:602750|HGNC:HGNC:2732|Ensembl:ENSG00000099977|Vega:OTTHUMG00000150798 +1653 DDX1 MIM:601257|HGNC:HGNC:2734|Ensembl:ENSG00000079785|Vega:OTTHUMG00000090593 +1654 DDX3X MIM:300160|HGNC:HGNC:2745|Ensembl:ENSG00000215301|Vega:OTTHUMG00000021369 +1655 DDX5 MIM:180630|HGNC:HGNC:2746|Ensembl:ENSG00000108654|Vega:OTTHUMG00000178936 +1656 DDX6 MIM:600326|HGNC:HGNC:2747|Ensembl:ENSG00000110367|Vega:OTTHUMG00000166411 +1657 DMXL1 MIM:605671|HGNC:HGNC:2937|Ensembl:ENSG00000172869|Vega:OTTHUMG00000128898 +1659 DHX8 MIM:600396|HGNC:HGNC:2749|Ensembl:ENSG00000067596|Vega:OTTHUMG00000180883 +1660 DHX9 MIM:603115|HGNC:HGNC:2750|Ensembl:ENSG00000135829|Vega:OTTHUMG00000035337 +1661 DHX9P1 HGNC:HGNC:2751 +1662 DDX10 MIM:601235|HGNC:HGNC:2735|Ensembl:ENSG00000178105|Vega:OTTHUMG00000166540 +1663 DDX11 MIM:601150|HGNC:HGNC:2736|Ensembl:ENSG00000013573|Vega:OTTHUMG00000168435 +1665 DHX15 MIM:603403|HGNC:HGNC:2738|Ensembl:ENSG00000109606|Vega:OTTHUMG00000160304 +1666 DECR1 MIM:222745|HGNC:HGNC:2753|Ensembl:ENSG00000104325|Vega:OTTHUMG00000163829 +1667 DEFA1 MIM:125220|HGNC:HGNC:2761|Ensembl:ENSG00000206047|Vega:OTTHUMG00000154594 +1668 DEFA3 MIM:604522|HGNC:HGNC:2762|Ensembl:ENSG00000239839|Vega:OTTHUMG00000090381 +1669 DEFA4 MIM:601157|HGNC:HGNC:2763|Ensembl:ENSG00000164821|Vega:OTTHUMG00000090382 +1670 DEFA5 MIM:600472|HGNC:HGNC:2764|Ensembl:ENSG00000164816|Vega:OTTHUMG00000090383 +1671 DEFA6 MIM:600471|HGNC:HGNC:2765|Ensembl:ENSG00000164822|Vega:OTTHUMG00000149984 +1672 DEFB1 MIM:602056|HGNC:HGNC:2766|Ensembl:ENSG00000164825|Vega:OTTHUMG00000090367 +1673 DEFB4A MIM:602215|HGNC:HGNC:2767|Ensembl:ENSG00000171711|Vega:OTTHUMG00000129314 +1674 DES MIM:125660|HGNC:HGNC:2770|Ensembl:ENSG00000175084|Vega:OTTHUMG00000058924 +1675 CFD MIM:134350|HGNC:HGNC:2771|Ensembl:ENSG00000197766|Vega:OTTHUMG00000181840 +1676 DFFA MIM:601882|HGNC:HGNC:2772|Ensembl:ENSG00000160049|Vega:OTTHUMG00000001909 +1677 DFFB MIM:601883|HGNC:HGNC:2773|Ensembl:ENSG00000169598|Vega:OTTHUMG00000003525 +1678 TIMM8A MIM:300356|HGNC:HGNC:11817|Ensembl:ENSG00000126953|Vega:OTTHUMG00000022028 +1680 DFNX3 MIM:300030|HGNC:HGNC:2777 +1681 DFN5 HGNC:HGNC:2778 +1684 DFN8 HGNC:HGNC:2781 +1687 DFNA5 MIM:608798|HGNC:HGNC:2810|Ensembl:ENSG00000105928|Vega:OTTHUMG00000023237 +1689 DFNA7 MIM:601412|HGNC:HGNC:2812 +1690 COCH MIM:603196|HGNC:HGNC:2180|Ensembl:ENSG00000100473|Vega:OTTHUMG00000029432 +1694 DFNA16 MIM:603964|HGNC:HGNC:2789 +1696 DFNA19 HGNC:HGNC:2791 +1697 DFNB5 MIM:600792|HGNC:HGNC:2837 +1705 DFNB13 MIM:603098|HGNC:HGNC:2819 +1706 DFNB14 MIM:603678|HGNC:HGNC:2820 +1709 DFNB17 MIM:603010|HGNC:HGNC:2823 +1712 DFNB19 HGNC:HGNC:2825 +1713 DFNB20 MIM:604060|HGNC:HGNC:2827 +1714 DGCR MIM:188400|HGNC:HGNC:2844 +1716 DGUOK MIM:601465|HGNC:HGNC:2858|Ensembl:ENSG00000114956|Vega:OTTHUMG00000129819 +1717 DHCR7 MIM:602858|HGNC:HGNC:2860|Ensembl:ENSG00000172893|Vega:OTTHUMG00000167346 +1718 DHCR24 MIM:606418|HGNC:HGNC:2859|Ensembl:ENSG00000116133|Vega:OTTHUMG00000009989 +1719 DHFR MIM:126060|HGNC:HGNC:2861|Ensembl:ENSG00000228716|Vega:OTTHUMG00000162529 +1720 DHFRP3 HGNC:HGNC:52354 +1723 DHODH MIM:126064|HGNC:HGNC:2867|Ensembl:ENSG00000102967|Vega:OTTHUMG00000178093 +1725 DHPS MIM:600944|HGNC:HGNC:2869|Ensembl:ENSG00000095059|Vega:OTTHUMG00000182618 +1727 CYB5R3 MIM:613213|HGNC:HGNC:2873|Ensembl:ENSG00000100243|Vega:OTTHUMG00000150745 +1728 NQO1 MIM:125860|HGNC:HGNC:2874|Ensembl:ENSG00000181019|Vega:OTTHUMG00000137575 +1729 DIAPH1 MIM:602121|HGNC:HGNC:2876|Ensembl:ENSG00000131504|Vega:OTTHUMG00000149893 +1730 DIAPH2 MIM:300108|HGNC:HGNC:2877|Ensembl:ENSG00000147202|Vega:OTTHUMG00000022689 +1731 SEPT1 MIM:612897|HGNC:HGNC:2879|Ensembl:ENSG00000180096|Vega:OTTHUMG00000176984 +1732 DIH1 MIM:142340|HGNC:HGNC:2881 +1733 DIO1 MIM:147892|HGNC:HGNC:2883|Ensembl:ENSG00000211452|Vega:OTTHUMG00000008435 +1734 DIO2 MIM:601413|HGNC:HGNC:2884|Ensembl:ENSG00000211448|Vega:OTTHUMG00000171443 +1735 DIO3 MIM:601038|HGNC:HGNC:2885|Ensembl:ENSG00000197406|Vega:OTTHUMG00000160681 +1736 DKC1 MIM:300126|HGNC:HGNC:2890|Ensembl:ENSG00000130826|Vega:OTTHUMG00000024242 +1737 DLAT MIM:608770|HGNC:HGNC:2896|Ensembl:ENSG00000150768|Vega:OTTHUMG00000133751 +1738 DLD MIM:238331|HGNC:HGNC:2898|Ensembl:ENSG00000091140|Vega:OTTHUMG00000154813 +1739 DLG1 MIM:601014|HGNC:HGNC:2900|Ensembl:ENSG00000075711|Vega:OTTHUMG00000047972 +1740 DLG2 MIM:603583|HGNC:HGNC:2901|Ensembl:ENSG00000150672|Vega:OTTHUMG00000134309 +1741 DLG3 MIM:300189|HGNC:HGNC:2902|Ensembl:ENSG00000082458|Vega:OTTHUMG00000021778 +1742 DLG4 MIM:602887|HGNC:HGNC:2903|Ensembl:ENSG00000132535|Vega:OTTHUMG00000134327 +1743 DLST MIM:126063|HGNC:HGNC:2911|Ensembl:ENSG00000119689|Vega:OTTHUMG00000171483 +1744 DLSTP1 HGNC:HGNC:2912 +1745 DLX1 MIM:600029|HGNC:HGNC:2914|Ensembl:ENSG00000144355|Vega:OTTHUMG00000073951 +1746 DLX2 MIM:126255|HGNC:HGNC:2915|Ensembl:ENSG00000115844|Vega:OTTHUMG00000132276 +1747 DLX3 MIM:600525|HGNC:HGNC:2916|Ensembl:ENSG00000064195|Vega:OTTHUMG00000161892 +1748 DLX4 MIM:601911|HGNC:HGNC:2917|Ensembl:ENSG00000108813|Vega:OTTHUMG00000161839 +1749 DLX5 MIM:600028|HGNC:HGNC:2918|Ensembl:ENSG00000105880|Vega:OTTHUMG00000154200 +1750 DLX6 MIM:600030|HGNC:HGNC:2919|Ensembl:ENSG00000006377|Vega:OTTHUMG00000154201 +1755 DMBT1 MIM:601969|HGNC:HGNC:2926|Ensembl:ENSG00000187908|Vega:OTTHUMG00000019185 +1756 DMD MIM:300377|HGNC:HGNC:2928|Ensembl:ENSG00000198947|Vega:OTTHUMG00000021336 +1757 SARDH MIM:604455|HGNC:HGNC:10536|Ensembl:ENSG00000123453|Vega:OTTHUMG00000020879 +1758 DMP1 MIM:600980|HGNC:HGNC:2932|Ensembl:ENSG00000152592|Vega:OTTHUMG00000130598 +1759 DNM1 MIM:602377|HGNC:HGNC:2972|Ensembl:ENSG00000106976|Vega:OTTHUMG00000020733 +1760 DMPK MIM:605377|HGNC:HGNC:2933|Ensembl:ENSG00000104936|Vega:OTTHUMG00000182334 +1761 DMRT1 MIM:602424|HGNC:HGNC:2934|Ensembl:ENSG00000137090|Vega:OTTHUMG00000019435 +1762 DMWD MIM:609857|HGNC:HGNC:2936|Ensembl:ENSG00000185800|Vega:OTTHUMG00000169044 +1763 DNA2 MIM:601810|HGNC:HGNC:2939|Ensembl:ENSG00000138346|Vega:OTTHUMG00000018352 +1767 DNAH5 MIM:603335|HGNC:HGNC:2950|Ensembl:ENSG00000039139|Vega:OTTHUMG00000090533 +1768 DNAH6 MIM:603336|HGNC:HGNC:2951|Ensembl:ENSG00000115423|Vega:OTTHUMG00000128957 +1769 DNAH8 MIM:603337|HGNC:HGNC:2952|Ensembl:ENSG00000124721|Vega:OTTHUMG00000016253 +1770 DNAH9 MIM:603330|HGNC:HGNC:2953|Ensembl:ENSG00000007174|Vega:OTTHUMG00000130383 +1773 DNASE1 MIM:125505|HGNC:HGNC:2956|Ensembl:ENSG00000213918|Vega:OTTHUMG00000129426 +1774 DNASE1L1 MIM:300081|HGNC:HGNC:2957|Ensembl:ENSG00000013563|Vega:OTTHUMG00000033188 +1775 DNASE1L2 MIM:602622|HGNC:HGNC:2958|Ensembl:ENSG00000167968|Vega:OTTHUMG00000177086 +1776 DNASE1L3 MIM:602244|HGNC:HGNC:2959|Ensembl:ENSG00000163687|Vega:OTTHUMG00000159153 +1777 DNASE2 MIM:126350|HGNC:HGNC:2960|Ensembl:ENSG00000105612|Vega:OTTHUMG00000180535 +1778 DYNC1H1 MIM:600112|HGNC:HGNC:2961|Ensembl:ENSG00000197102|Vega:OTTHUMG00000171644 +1780 DYNC1I1 MIM:603772|HGNC:HGNC:2963|Ensembl:ENSG00000158560|Vega:OTTHUMG00000153983 +1781 DYNC1I2 MIM:603331|HGNC:HGNC:2964|Ensembl:ENSG00000077380|Vega:OTTHUMG00000154061 +1783 DYNC1LI2 MIM:611406|HGNC:HGNC:2966|Ensembl:ENSG00000135720|Vega:OTTHUMG00000137523 +1784 DNCM MIM:126330 +1785 DNM2 MIM:602378|HGNC:HGNC:2974|Ensembl:ENSG00000079805|Vega:OTTHUMG00000180694 +1786 DNMT1 MIM:126375|HGNC:HGNC:2976|Ensembl:ENSG00000130816|Vega:OTTHUMG00000180397 +1787 TRDMT1 MIM:602478|HGNC:HGNC:2977|Ensembl:ENSG00000107614|Vega:OTTHUMG00000017745 +1788 DNMT3A MIM:602769|HGNC:HGNC:2978|Ensembl:ENSG00000119772|Vega:OTTHUMG00000094777 +1789 DNMT3B MIM:602900|HGNC:HGNC:2979|Ensembl:ENSG00000088305|Vega:OTTHUMG00000032226 +1791 DNTT MIM:187410|HGNC:HGNC:2983|Ensembl:ENSG00000107447|Vega:OTTHUMG00000018832 +1793 DOCK1 MIM:601403|HGNC:HGNC:2987|Ensembl:ENSG00000150760|Vega:OTTHUMG00000019249 +1794 DOCK2 MIM:603122|HGNC:HGNC:2988|Ensembl:ENSG00000134516|Vega:OTTHUMG00000130437 +1795 DOCK3 MIM:603123|HGNC:HGNC:2989|Ensembl:ENSG00000088538|Vega:OTTHUMG00000156892 +1796 DOK1 MIM:602919|HGNC:HGNC:2990|Ensembl:ENSG00000115325|Vega:OTTHUMG00000129956 +1797 DXO MIM:605996|HGNC:HGNC:2992|Ensembl:ENSG00000204348|Vega:OTTHUMG00000031272 +1798 DPAGT1 MIM:191350|HGNC:HGNC:2995|Ensembl:ENSG00000172269|Vega:OTTHUMG00000153533 +1800 DPEP1 MIM:179780|HGNC:HGNC:3002|Ensembl:ENSG00000015413|Vega:OTTHUMG00000138052 +1801 DPH1 MIM:603527|HGNC:HGNC:3003|Ensembl:ENSG00000108963|Vega:OTTHUMG00000177724 +1802 DPH2 MIM:603456|HGNC:HGNC:3004|Ensembl:ENSG00000132768|Vega:OTTHUMG00000008295 +1803 DPP4 MIM:102720|HGNC:HGNC:3009|Ensembl:ENSG00000197635|Vega:OTTHUMG00000132056 +1804 DPP6 MIM:126141|HGNC:HGNC:3010|Ensembl:ENSG00000130226|Vega:OTTHUMG00000151511 +1805 DPT MIM:125597|HGNC:HGNC:3011|Ensembl:ENSG00000143196|Vega:OTTHUMG00000034554 +1806 DPYD MIM:612779|HGNC:HGNC:3012|Ensembl:ENSG00000188641|Vega:OTTHUMG00000039683 +1807 DPYS MIM:613326|HGNC:HGNC:3013|Ensembl:ENSG00000147647|Vega:OTTHUMG00000164891 +1808 DPYSL2 MIM:602463|HGNC:HGNC:3014|Ensembl:ENSG00000092964|Vega:OTTHUMG00000099439 +1809 DPYSL3 MIM:601168|HGNC:HGNC:3015|Ensembl:ENSG00000113657|Vega:OTTHUMG00000163437 +1810 DR1 MIM:601482|HGNC:HGNC:3017|Ensembl:ENSG00000117505|Vega:OTTHUMG00000010862 +1811 SLC26A3 MIM:126650|HGNC:HGNC:3018|Ensembl:ENSG00000091138|Vega:OTTHUMG00000154812 +1812 DRD1 MIM:126449|HGNC:HGNC:3020|Ensembl:ENSG00000184845|Vega:OTTHUMG00000130557 +1813 DRD2 MIM:126450|HGNC:HGNC:3023|Ensembl:ENSG00000149295|Vega:OTTHUMG00000167717 +1814 DRD3 MIM:126451|HGNC:HGNC:3024|Ensembl:ENSG00000151577|Vega:OTTHUMG00000159334 +1815 DRD4 MIM:126452|HGNC:HGNC:3025|Ensembl:ENSG00000069696|Vega:OTTHUMG00000133312 +1816 DRD5 MIM:126453|HGNC:HGNC:3026|Ensembl:ENSG00000169676|Vega:OTTHUMG00000128489 +1817 DRD5P1 HGNC:HGNC:3027 +1818 DRD5P2 HGNC:HGNC:3028 +1819 DRG2 MIM:602986|HGNC:HGNC:3030|Ensembl:ENSG00000108591|Vega:OTTHUMG00000059399 +1820 ARID3A MIM:603265|HGNC:HGNC:3031|Ensembl:ENSG00000116017|Vega:OTTHUMG00000182018 +1821 DRP2 MIM:300052|HGNC:HGNC:3032|Ensembl:ENSG00000102385|Vega:OTTHUMG00000022020 +1822 ATN1 MIM:607462|HGNC:HGNC:3033|Ensembl:ENSG00000111676|Vega:OTTHUMG00000169015 +1823 DSC1 MIM:125643|HGNC:HGNC:3035|Ensembl:ENSG00000134765|Vega:OTTHUMG00000131982 +1824 DSC2 MIM:125645|HGNC:HGNC:3036|Ensembl:ENSG00000134755|Vega:OTTHUMG00000131981 +1825 DSC3 MIM:600271|HGNC:HGNC:3037|Ensembl:ENSG00000134762|Vega:OTTHUMG00000179622 +1826 DSCAM MIM:602523|HGNC:HGNC:3039|Ensembl:ENSG00000171587|Vega:OTTHUMG00000086732 +1827 RCAN1 MIM:602917|HGNC:HGNC:3040|Ensembl:ENSG00000159200|Vega:OTTHUMG00000086235 +1828 DSG1 MIM:125670|HGNC:HGNC:3048|Ensembl:ENSG00000134760|Vega:OTTHUMG00000131983 +1829 DSG2 MIM:125671|HGNC:HGNC:3049|Ensembl:ENSG00000046604|Vega:OTTHUMG00000179649 +1830 DSG3 MIM:169615|HGNC:HGNC:3050|Ensembl:ENSG00000134757|Vega:OTTHUMG00000131985 +1831 TSC22D3 MIM:300506|HGNC:HGNC:3051|Ensembl:ENSG00000157514|Vega:OTTHUMG00000022168 +1832 DSP MIM:125647|HGNC:HGNC:3052|Ensembl:ENSG00000096696|Vega:OTTHUMG00000014212 +1833 EPYC MIM:601657|HGNC:HGNC:3053|Ensembl:ENSG00000083782|Vega:OTTHUMG00000170072 +1834 DSPP MIM:125485|HGNC:HGNC:3054|Ensembl:ENSG00000152591|Vega:OTTHUMG00000161061 +1836 SLC26A2 MIM:606718|HGNC:HGNC:10994|Ensembl:ENSG00000155850|Vega:OTTHUMG00000130054 +1837 DTNA MIM:601239|HGNC:HGNC:3057|Ensembl:ENSG00000134769|Vega:OTTHUMG00000132309 +1838 DTNB MIM:602415|HGNC:HGNC:3058|Ensembl:ENSG00000138101|Vega:OTTHUMG00000152129 +1839 HBEGF MIM:126150|HGNC:HGNC:3059|Ensembl:ENSG00000113070|Vega:OTTHUMG00000129496 +1840 DTX1 MIM:602582|HGNC:HGNC:3060|Ensembl:ENSG00000135144|Vega:OTTHUMG00000169610 +1841 DTYMK MIM:188345|HGNC:HGNC:3061|Ensembl:ENSG00000168393|Vega:OTTHUMG00000133409 +1842 ECM2 MIM:603479|HGNC:HGNC:3154|Ensembl:ENSG00000106823|Vega:OTTHUMG00000020226 +1843 DUSP1 MIM:600714|HGNC:HGNC:3064|Ensembl:ENSG00000120129|Vega:OTTHUMG00000130523 +1844 DUSP2 MIM:603068|HGNC:HGNC:3068|Ensembl:ENSG00000158050|Vega:OTTHUMG00000130456 +1845 DUSP3 MIM:600183|HGNC:HGNC:3069|Ensembl:ENSG00000108861|Vega:OTTHUMG00000180889 +1846 DUSP4 MIM:602747|HGNC:HGNC:3070|Ensembl:ENSG00000120875|Vega:OTTHUMG00000133395 +1847 DUSP5 MIM:603069|HGNC:HGNC:3071|Ensembl:ENSG00000138166|Vega:OTTHUMG00000019040 +1848 DUSP6 MIM:602748|HGNC:HGNC:3072|Ensembl:ENSG00000139318|Vega:OTTHUMG00000169912 +1849 DUSP7 MIM:602749|HGNC:HGNC:3073|Ensembl:ENSG00000164086|Vega:OTTHUMG00000157819 +1850 DUSP8 MIM:602038|HGNC:HGNC:3074|Ensembl:ENSG00000184545|Vega:OTTHUMG00000133348 +1852 DUSP9 MIM:300134|HGNC:HGNC:3076|Ensembl:ENSG00000130829|Vega:OTTHUMG00000024211 +1854 DUT MIM:601266|HGNC:HGNC:3078|Ensembl:ENSG00000128951|Vega:OTTHUMG00000172155 +1855 DVL1 MIM:601365|HGNC:HGNC:3084|Ensembl:ENSG00000107404|Vega:OTTHUMG00000003069 +1856 DVL2 MIM:602151|HGNC:HGNC:3086|Ensembl:ENSG00000004975|Vega:OTTHUMG00000102155 +1857 DVL3 MIM:601368|HGNC:HGNC:3087|Ensembl:ENSG00000161202|Vega:OTTHUMG00000156841 +1858 DWS MIM:220200|HGNC:HGNC:3088 +1859 DYRK1A MIM:600855|HGNC:HGNC:3091|Ensembl:ENSG00000157540|Vega:OTTHUMG00000086657 +1861 TOR1A MIM:605204|HGNC:HGNC:3098|Ensembl:ENSG00000136827|Vega:OTTHUMG00000020794 +1862 DYT2 MIM:224500|HGNC:HGNC:3102 +1866 DYT7 MIM:602124|HGNC:HGNC:3107 +1867 DYX1 MIM:127700|HGNC:HGNC:3108 +1869 E2F1 MIM:189971|HGNC:HGNC:3113|Ensembl:ENSG00000101412|Vega:OTTHUMG00000032265 +1870 E2F2 MIM:600426|HGNC:HGNC:3114|Ensembl:ENSG00000007968|Vega:OTTHUMG00000003223 +1871 E2F3 MIM:600427|HGNC:HGNC:3115|Ensembl:ENSG00000112242|Vega:OTTHUMG00000016389 +1872 E2F3P1 HGNC:HGNC:3116 +1874 E2F4 MIM:600659|HGNC:HGNC:3118|Ensembl:ENSG00000205250|Vega:OTTHUMG00000172975 +1875 E2F5 MIM:600967|HGNC:HGNC:3119|Ensembl:ENSG00000133740|Vega:OTTHUMG00000164785 +1876 E2F6 MIM:602944|HGNC:HGNC:3120|Ensembl:ENSG00000169016|Vega:OTTHUMG00000090565 +1877 E4F1 MIM:603022|HGNC:HGNC:3121|Ensembl:ENSG00000167967|Vega:OTTHUMG00000177084 +1878 E11S MIM:129150|HGNC:HGNC:3112 +1879 EBF1 MIM:164343|HGNC:HGNC:3126|Ensembl:ENSG00000164330|Vega:OTTHUMG00000130304 +1880 GPR183 MIM:605741|HGNC:HGNC:3128|Ensembl:ENSG00000169508|Vega:OTTHUMG00000017263 +1881 EBM MIM:302000|HGNC:HGNC:3130 +1884 EBR3 MIM:226500|HGNC:HGNC:3136 +1885 EBR4 HGNC:HGNC:3137 +1888 EBVS1 MIM:132850|HGNC:HGNC:3143 +1889 ECE1 MIM:600423|HGNC:HGNC:3146|Ensembl:ENSG00000117298|Vega:OTTHUMG00000002625 +1890 TYMP MIM:131222|HGNC:HGNC:3148|Ensembl:ENSG00000025708|Vega:OTTHUMG00000150249 +1891 ECH1 MIM:600696|HGNC:HGNC:3149|Ensembl:ENSG00000104823|Vega:OTTHUMG00000182609 +1892 ECHS1 MIM:602292|HGNC:HGNC:3151|Ensembl:ENSG00000127884|Vega:OTTHUMG00000019320 +1893 ECM1 MIM:602201|HGNC:HGNC:3153|Ensembl:ENSG00000143369|Vega:OTTHUMG00000012806 +1894 ECT2 MIM:600586|HGNC:HGNC:3155|Ensembl:ENSG00000114346|Vega:OTTHUMG00000156762 +1896 EDA MIM:300451|HGNC:HGNC:3157|Ensembl:ENSG00000158813|Vega:OTTHUMG00000021764 +1901 S1PR1 MIM:601974|HGNC:HGNC:3165|Ensembl:ENSG00000170989|Vega:OTTHUMG00000010835 +1902 LPAR1 MIM:602282|HGNC:HGNC:3166|Ensembl:ENSG00000198121|Vega:OTTHUMG00000020486 +1903 S1PR3 MIM:601965|HGNC:HGNC:3167|Ensembl:ENSG00000213694|Vega:OTTHUMG00000020173 +1906 EDN1 MIM:131240|HGNC:HGNC:3176|Ensembl:ENSG00000078401|Vega:OTTHUMG00000014266 +1907 EDN2 MIM:131241|HGNC:HGNC:3177|Ensembl:ENSG00000127129|Vega:OTTHUMG00000006362 +1908 EDN3 MIM:131242|HGNC:HGNC:3178|Ensembl:ENSG00000124205|Vega:OTTHUMG00000032867 +1909 EDNRA MIM:131243|HGNC:HGNC:3179|Ensembl:ENSG00000151617|Vega:OTTHUMG00000161354 +1910 EDNRB MIM:131244|HGNC:HGNC:3180|Ensembl:ENSG00000136160|Vega:OTTHUMG00000017111 +1911 PHC1 MIM:602978|HGNC:HGNC:3182|Ensembl:ENSG00000111752|Vega:OTTHUMG00000168275 +1912 PHC2 MIM:602979|HGNC:HGNC:3183|Ensembl:ENSG00000134686|Vega:OTTHUMG00000004133 +1913 EEC1 MIM:129900|HGNC:HGNC:3186 +1914 EEC2 HGNC:HGNC:3187 +1915 EEF1A1 MIM:130590|HGNC:HGNC:3189|Ensembl:ENSG00000156508|Vega:OTTHUMG00000015031 +1917 EEF1A2 MIM:602959|HGNC:HGNC:3192|Ensembl:ENSG00000101210|Vega:OTTHUMG00000033076 +1918 EEF1A1P43 HGNC:HGNC:3193 +1932 EEF1B2P1 HGNC:HGNC:3207 +1933 EEF1B2 MIM:600655|HGNC:HGNC:3208|Ensembl:ENSG00000114942 +1934 EEF1B2P2 HGNC:HGNC:3209 +1936 EEF1D MIM:130592|HGNC:HGNC:3211|Ensembl:ENSG00000104529|Vega:OTTHUMG00000165191 +1937 EEF1G MIM:130593|HGNC:HGNC:3213|Ensembl:ENSG00000254772|Vega:OTTHUMG00000167567 +1938 EEF2 MIM:130610|HGNC:HGNC:3214|Ensembl:ENSG00000167658|Vega:OTTHUMG00000181790 +1939 EIF2D MIM:613709|HGNC:HGNC:6583|Ensembl:ENSG00000143486|Vega:OTTHUMG00000184619 +1940 EEGV1 MIM:130180|HGNC:HGNC:3215 +1942 EFNA1 MIM:191164|HGNC:HGNC:3221|Ensembl:ENSG00000169242|Vega:OTTHUMG00000035312 +1943 EFNA2 MIM:602756|HGNC:HGNC:3222|Ensembl:ENSG00000099617|Vega:OTTHUMG00000180148 +1944 EFNA3 MIM:601381|HGNC:HGNC:3223|Ensembl:ENSG00000143590|Vega:OTTHUMG00000035313 +1945 EFNA4 MIM:601380|HGNC:HGNC:3224|Ensembl:ENSG00000243364|Vega:OTTHUMG00000035309 +1946 EFNA5 MIM:601535|HGNC:HGNC:3225|Ensembl:ENSG00000184349|Vega:OTTHUMG00000128741 +1947 EFNB1 MIM:300035|HGNC:HGNC:3226|Ensembl:ENSG00000090776|Vega:OTTHUMG00000021751 +1948 EFNB2 MIM:600527|HGNC:HGNC:3227|Ensembl:ENSG00000125266|Vega:OTTHUMG00000017324 +1949 EFNB3 MIM:602297|HGNC:HGNC:3228|Ensembl:ENSG00000108947|Vega:OTTHUMG00000108161 +1950 EGF MIM:131530|HGNC:HGNC:3229|Ensembl:ENSG00000138798|Vega:OTTHUMG00000132044 +1951 CELSR3 MIM:604264|HGNC:HGNC:3230|Ensembl:ENSG00000008300|Vega:OTTHUMG00000133544 +1952 CELSR2 MIM:604265|HGNC:HGNC:3231|Ensembl:ENSG00000143126|Vega:OTTHUMG00000012003 +1953 MEGF6 MIM:604266|HGNC:HGNC:3232|Ensembl:ENSG00000162591|Vega:OTTHUMG00000000611 +1954 MEGF8 MIM:604267|HGNC:HGNC:3233|Ensembl:ENSG00000105429|Vega:OTTHUMG00000150342 +1955 MEGF9 MIM:604268|HGNC:HGNC:3234|Ensembl:ENSG00000106780|Vega:OTTHUMG00000021039 +1956 EGFR MIM:131550|HGNC:HGNC:3236|Ensembl:ENSG00000146648|Vega:OTTHUMG00000023661 +1957 EGI MIM:600669|HGNC:HGNC:3237 +1958 EGR1 MIM:128990|HGNC:HGNC:3238|Ensembl:ENSG00000120738|Vega:OTTHUMG00000129197 +1959 EGR2 MIM:129010|HGNC:HGNC:3239|Ensembl:ENSG00000122877|Vega:OTTHUMG00000018308 +1960 EGR3 MIM:602419|HGNC:HGNC:3240|Ensembl:ENSG00000179388|Vega:OTTHUMG00000097825 +1961 EGR4 MIM:128992|HGNC:HGNC:3241|Ensembl:ENSG00000135625|Vega:OTTHUMG00000129774 +1962 EHHADH MIM:607037|HGNC:HGNC:3247|Ensembl:ENSG00000113790|Vega:OTTHUMG00000156698 +1964 EIF1AX MIM:300186|HGNC:HGNC:3250|Ensembl:ENSG00000173674|Vega:OTTHUMG00000022704 +1965 EIF2S1 MIM:603907|HGNC:HGNC:3265|Ensembl:ENSG00000134001|Vega:OTTHUMG00000029800 +1967 EIF2B1 MIM:606686|HGNC:HGNC:3257|Ensembl:ENSG00000111361|Vega:OTTHUMG00000168696 +1968 EIF2S3 MIM:300161|HGNC:HGNC:3267|Ensembl:ENSG00000130741|Vega:OTTHUMG00000021262 +1969 EPHA2 MIM:176946|HGNC:HGNC:3386|Ensembl:ENSG00000142627|Vega:OTTHUMG00000009527 +1973 EIF4A1 MIM:602641|HGNC:HGNC:3282|Ensembl:ENSG00000161960|Vega:OTTHUMG00000108149 +1974 EIF4A2 MIM:601102|HGNC:HGNC:3284|Ensembl:ENSG00000156976|Vega:OTTHUMG00000156564 +1975 EIF4B MIM:603928|HGNC:HGNC:3285|Ensembl:ENSG00000063046|Vega:OTTHUMG00000169570 +1977 EIF4E MIM:133440|HGNC:HGNC:3287|Ensembl:ENSG00000151247|Vega:OTTHUMG00000161090 +1978 EIF4EBP1 MIM:602223|HGNC:HGNC:3288|Ensembl:ENSG00000187840|Vega:OTTHUMG00000164012 +1979 EIF4EBP2 MIM:602224|HGNC:HGNC:3289|Ensembl:ENSG00000148730|Vega:OTTHUMG00000018409 +1980 EIF4EP1 HGNC:HGNC:3292 +1981 EIF4G1 MIM:600495|HGNC:HGNC:3296|Ensembl:ENSG00000114867|Vega:OTTHUMG00000156784 +1982 EIF4G2 MIM:602325|HGNC:HGNC:3297|Ensembl:ENSG00000110321|Vega:OTTHUMG00000165823 +1983 EIF5 MIM:601710|HGNC:HGNC:3299|Ensembl:ENSG00000100664|Vega:OTTHUMG00000171839 +1984 EIF5A MIM:600187|HGNC:HGNC:3300|Ensembl:ENSG00000132507|Vega:OTTHUMG00000102197 +1986 EIF5AP2 HGNC:HGNC:3303 +1987 EIF5AP3 HGNC:HGNC:3304 +1990 CELA1 MIM:130120|HGNC:HGNC:3308|Ensembl:ENSG00000139610|Vega:OTTHUMG00000167523 +1991 ELANE MIM:130130|HGNC:HGNC:3309|Ensembl:ENSG00000197561|Vega:OTTHUMG00000181839 +1992 SERPINB1 MIM:130135|HGNC:HGNC:3311|Ensembl:ENSG00000021355|Vega:OTTHUMG00000014124 +1993 ELAVL2 MIM:601673|HGNC:HGNC:3313|Ensembl:ENSG00000107105|Vega:OTTHUMG00000019700 +1994 ELAVL1 MIM:603466|HGNC:HGNC:3312|Ensembl:ENSG00000066044|Vega:OTTHUMG00000182470 +1995 ELAVL3 MIM:603458|HGNC:HGNC:3314|Ensembl:ENSG00000196361|Vega:OTTHUMG00000182030 +1996 ELAVL4 MIM:168360|HGNC:HGNC:3315|Ensembl:ENSG00000162374|Vega:OTTHUMG00000007877 +1997 ELF1 MIM:189973|HGNC:HGNC:3316|Ensembl:ENSG00000120690|Vega:OTTHUMG00000016783 +1998 ELF2 HGNC:HGNC:3317|Ensembl:ENSG00000109381|Vega:OTTHUMG00000133383 +1999 ELF3 MIM:602191|HGNC:HGNC:3318|Ensembl:ENSG00000163435|Vega:OTTHUMG00000035867 +2000 ELF4 MIM:300775|HGNC:HGNC:3319|Ensembl:ENSG00000102034|Vega:OTTHUMG00000022390 +2001 ELF5 MIM:605169|HGNC:HGNC:3320|Ensembl:ENSG00000135374|Vega:OTTHUMG00000166451 +2002 ELK1 MIM:311040|HGNC:HGNC:3321|Ensembl:ENSG00000126767|Vega:OTTHUMG00000021452 +2003 ELK2AP HGNC:HGNC:3323 +2004 ELK3 MIM:600247|HGNC:HGNC:3325|Ensembl:ENSG00000111145|Vega:OTTHUMG00000170364 +2005 ELK4 MIM:600246|HGNC:HGNC:3326|Ensembl:ENSG00000158711|Vega:OTTHUMG00000037221 +2006 ELN MIM:130160|HGNC:HGNC:3327|Ensembl:ENSG00000049540|Vega:OTTHUMG00000150229 +2009 EML1 MIM:602033|HGNC:HGNC:3330|Ensembl:ENSG00000066629|Vega:OTTHUMG00000171529 +2010 EMD MIM:300384|HGNC:HGNC:3331|Ensembl:ENSG00000102119|Vega:OTTHUMG00000033186 +2011 MARK2 MIM:600526|HGNC:HGNC:3332|Ensembl:ENSG00000072518|Vega:OTTHUMG00000160504 +2012 EMP1 MIM:602333|HGNC:HGNC:3333|Ensembl:ENSG00000134531|Vega:OTTHUMG00000168775 +2013 EMP2 MIM:602334|HGNC:HGNC:3334|Ensembl:ENSG00000213853|Vega:OTTHUMG00000129752 +2014 EMP3 MIM:602335|HGNC:HGNC:3335|Ensembl:ENSG00000142227|Vega:OTTHUMG00000183196 +2015 ADGRE1 MIM:600493|HGNC:HGNC:3336|Ensembl:ENSG00000174837|Vega:OTTHUMG00000181966 +2016 EMX1 MIM:600034|HGNC:HGNC:3340|Ensembl:ENSG00000135638|Vega:OTTHUMG00000129778 +2017 CTTN MIM:164765|HGNC:HGNC:3338|Ensembl:ENSG00000085733|Vega:OTTHUMG00000134307 +2018 EMX2 MIM:600035|HGNC:HGNC:3341|Ensembl:ENSG00000170370|Vega:OTTHUMG00000019123 +2019 EN1 MIM:131290|HGNC:HGNC:3342|Ensembl:ENSG00000163064|Vega:OTTHUMG00000131401 +2020 EN2 MIM:131310|HGNC:HGNC:3343|Ensembl:ENSG00000164778|Vega:OTTHUMG00000151354 +2021 ENDOG MIM:600440|HGNC:HGNC:3346|Ensembl:ENSG00000167136|Vega:OTTHUMG00000020763 +2022 ENG MIM:131195|HGNC:HGNC:3349|Ensembl:ENSG00000106991|Vega:OTTHUMG00000020723 +2023 ENO1 MIM:172430|HGNC:HGNC:3350|Ensembl:ENSG00000074800|Vega:OTTHUMG00000001773 +2025 ENO1P1 HGNC:HGNC:3352 +2026 ENO2 MIM:131360|HGNC:HGNC:3353|Ensembl:ENSG00000111674|Vega:OTTHUMG00000168967 +2027 ENO3 MIM:131370|HGNC:HGNC:3354|Ensembl:ENSG00000108515|Vega:OTTHUMG00000099394 +2028 ENPEP MIM:138297|HGNC:HGNC:3355|Ensembl:ENSG00000138792|Vega:OTTHUMG00000132546 +2029 ENSA MIM:603061|HGNC:HGNC:3360|Ensembl:ENSG00000143420|Vega:OTTHUMG00000035004 +2030 SLC29A1 MIM:602193|HGNC:HGNC:11003|Ensembl:ENSG00000112759|Vega:OTTHUMG00000014759 +2031 ENUR1 MIM:600631|HGNC:HGNC:3369 +2032 ENUR2 MIM:600808|HGNC:HGNC:3370 +2033 EP300 MIM:602700|HGNC:HGNC:3373|Ensembl:ENSG00000100393|Vega:OTTHUMG00000150937 +2034 EPAS1 MIM:603349|HGNC:HGNC:3374|Ensembl:ENSG00000116016|Vega:OTTHUMG00000128818 +2035 EPB41 MIM:130500|HGNC:HGNC:3377|Ensembl:ENSG00000159023|Vega:OTTHUMG00000003644 +2036 EPB41L1 MIM:602879|HGNC:HGNC:3378|Ensembl:ENSG00000088367|Vega:OTTHUMG00000032378 +2037 EPB41L2 MIM:603237|HGNC:HGNC:3379|Ensembl:ENSG00000079819|Vega:OTTHUMG00000015560 +2038 EPB42 MIM:177070|HGNC:HGNC:3381|Ensembl:ENSG00000166947|Vega:OTTHUMG00000130701 +2039 DMTN MIM:125305|HGNC:HGNC:3382|Ensembl:ENSG00000158856|Vega:OTTHUMG00000097087 +2040 STOM MIM:133090|HGNC:HGNC:3383|Ensembl:ENSG00000148175|Vega:OTTHUMG00000020590 +2041 EPHA1 MIM:179610|HGNC:HGNC:3385|Ensembl:ENSG00000146904|Vega:OTTHUMG00000155894 +2042 EPHA3 MIM:179611|HGNC:HGNC:3387|Ensembl:ENSG00000044524|Vega:OTTHUMG00000159040 +2043 EPHA4 MIM:602188|HGNC:HGNC:3388|Ensembl:ENSG00000116106|Vega:OTTHUMG00000133142 +2044 EPHA5 MIM:600004|HGNC:HGNC:3389|Ensembl:ENSG00000145242|Vega:OTTHUMG00000129273 +2045 EPHA7 MIM:602190|HGNC:HGNC:3390|Ensembl:ENSG00000135333|Vega:OTTHUMG00000015228 +2046 EPHA8 MIM:176945|HGNC:HGNC:3391|Ensembl:ENSG00000070886|Vega:OTTHUMG00000002892 +2047 EPHB1 MIM:600600|HGNC:HGNC:3392|Ensembl:ENSG00000154928|Vega:OTTHUMG00000159804 +2048 EPHB2 MIM:600997|HGNC:HGNC:3393|Ensembl:ENSG00000133216|Vega:OTTHUMG00000002881 +2049 EPHB3 MIM:601839|HGNC:HGNC:3394|Ensembl:ENSG00000182580|Vega:OTTHUMG00000156710 +2050 EPHB4 MIM:600011|HGNC:HGNC:3395|Ensembl:ENSG00000196411|Vega:OTTHUMG00000157040 +2051 EPHB6 MIM:602757|HGNC:HGNC:3396|Ensembl:ENSG00000106123|Vega:OTTHUMG00000155707 +2052 EPHX1 MIM:132810|HGNC:HGNC:3401|Ensembl:ENSG00000143819|Vega:OTTHUMG00000037743 +2053 EPHX2 MIM:132811|HGNC:HGNC:3402|Ensembl:ENSG00000120915|Vega:OTTHUMG00000102115 +2054 STX2 MIM:132350|HGNC:HGNC:3403|Ensembl:ENSG00000111450|Vega:OTTHUMG00000168365 +2055 CLN8 MIM:607837|HGNC:HGNC:2079|Ensembl:ENSG00000182372|Vega:OTTHUMG00000090343 +2056 EPO MIM:133170|HGNC:HGNC:3415|Ensembl:ENSG00000130427|Vega:OTTHUMG00000152121 +2057 EPOR MIM:133171|HGNC:HGNC:3416|Ensembl:ENSG00000187266|Vega:OTTHUMG00000182027 +2058 EPRS MIM:138295|HGNC:HGNC:3418|Ensembl:ENSG00000136628|Vega:OTTHUMG00000037433 +2059 EPS8 MIM:600206|HGNC:HGNC:3420|Ensembl:ENSG00000151491|Vega:OTTHUMG00000168787 +2060 EPS15 MIM:600051|HGNC:HGNC:3419|Ensembl:ENSG00000085832|Vega:OTTHUMG00000008192 +2063 NR2F6 MIM:132880|HGNC:HGNC:7977|Ensembl:ENSG00000160113|Vega:OTTHUMG00000182728 +2064 ERBB2 MIM:164870|HGNC:HGNC:3430|Ensembl:ENSG00000141736|Vega:OTTHUMG00000179300 +2065 ERBB3 MIM:190151|HGNC:HGNC:3431|Ensembl:ENSG00000065361|Vega:OTTHUMG00000170140 +2066 ERBB4 MIM:600543|HGNC:HGNC:3432|Ensembl:ENSG00000178568|Vega:OTTHUMG00000133012 +2067 ERCC1 MIM:126380|HGNC:HGNC:3433|Ensembl:ENSG00000012061|Vega:OTTHUMG00000182121 +2068 ERCC2 MIM:126340|HGNC:HGNC:3434|Ensembl:ENSG00000104884|Vega:OTTHUMG00000048190 +2069 EREG MIM:602061|HGNC:HGNC:3443|Ensembl:ENSG00000124882|Vega:OTTHUMG00000130005 +2070 EYA4 MIM:603550|HGNC:HGNC:3522|Ensembl:ENSG00000112319|Vega:OTTHUMG00000015602 +2071 ERCC3 MIM:133510|HGNC:HGNC:3435|Ensembl:ENSG00000163161|Vega:OTTHUMG00000131530 +2072 ERCC4 MIM:133520|HGNC:HGNC:3436|Ensembl:ENSG00000175595|Vega:OTTHUMG00000048194 +2073 ERCC5 MIM:133530|HGNC:HGNC:3437|Ensembl:ENSG00000134899|Vega:OTTHUMG00000017310 +2074 ERCC6 MIM:609413|HGNC:HGNC:3438|Ensembl:ENSG00000225830|Vega:OTTHUMG00000018195 +2076 ERCM1 MIM:133535|HGNC:HGNC:3440 +2077 ERF MIM:611888|HGNC:HGNC:3444|Ensembl:ENSG00000105722|Vega:OTTHUMG00000182788 +2078 ERG MIM:165080|HGNC:HGNC:3446|Ensembl:ENSG00000157554|Vega:OTTHUMG00000090767 +2079 ERH MIM:601191|HGNC:HGNC:3447|Ensembl:ENSG00000100632|Vega:OTTHUMG00000171323 +2081 ERN1 MIM:604033|HGNC:HGNC:3449|Ensembl:ENSG00000178607|Vega:OTTHUMG00000178879 +2086 ERV3-1 MIM:131170|HGNC:HGNC:3454|Ensembl:ENSG00000213462|Vega:OTTHUMG00000165023 +2090 ESA4 MIM:133220|HGNC:HGNC:3462 +2091 FBL MIM:134795|HGNC:HGNC:3599|Ensembl:ENSG00000105202|Vega:OTTHUMG00000182581 +2096 ESAT MIM:133250|HGNC:HGNC:3463 +2097 ESB3 MIM:133290|HGNC:HGNC:3464 +2098 ESD MIM:133280|HGNC:HGNC:3465|Ensembl:ENSG00000139684|Vega:OTTHUMG00000016878 +2099 ESR1 MIM:133430|HGNC:HGNC:3467|Ensembl:ENSG00000091831|Vega:OTTHUMG00000016103 +2100 ESR2 MIM:601663|HGNC:HGNC:3468|Ensembl:ENSG00000140009|Vega:OTTHUMG00000141306 +2101 ESRRA MIM:601998|HGNC:HGNC:3471|Ensembl:ENSG00000173153|Vega:OTTHUMG00000150641 +2103 ESRRB MIM:602167|HGNC:HGNC:3473|Ensembl:ENSG00000119715|Vega:OTTHUMG00000160457 +2104 ESRRG MIM:602969|HGNC:HGNC:3474|Ensembl:ENSG00000196482|Vega:OTTHUMG00000037025 +2107 ETF1 MIM:600285|HGNC:HGNC:3477|Ensembl:ENSG00000120705|Vega:OTTHUMG00000129199 +2108 ETFA MIM:608053|HGNC:HGNC:3481|Ensembl:ENSG00000140374|Vega:OTTHUMG00000172586 +2109 ETFB MIM:130410|HGNC:HGNC:3482|Ensembl:ENSG00000105379|Vega:OTTHUMG00000182903 +2110 ETFDH MIM:231675|HGNC:HGNC:3483|Ensembl:ENSG00000171503|Vega:OTTHUMG00000161684 +2112 ETM2 MIM:602134|HGNC:HGNC:3487 +2113 ETS1 MIM:164720|HGNC:HGNC:3488|Ensembl:ENSG00000134954|Vega:OTTHUMG00000165799 +2114 ETS2 MIM:164740|HGNC:HGNC:3489|Ensembl:ENSG00000157557|Vega:OTTHUMG00000090769 +2115 ETV1 MIM:600541|HGNC:HGNC:3490|Ensembl:ENSG00000006468|Vega:OTTHUMG00000152403 +2116 ETV2 MIM:609358|HGNC:HGNC:3491|Ensembl:ENSG00000105672|Vega:OTTHUMG00000150545 +2117 ETV3 MIM:164873|HGNC:HGNC:3492|Ensembl:ENSG00000117036|Vega:OTTHUMG00000034298 +2118 ETV4 MIM:600711|HGNC:HGNC:3493|Ensembl:ENSG00000175832|Vega:OTTHUMG00000180884 +2119 ETV5 MIM:601600|HGNC:HGNC:3494|Ensembl:ENSG00000244405|Vega:OTTHUMG00000156639 +2120 ETV6 MIM:600618|HGNC:HGNC:3495|Ensembl:ENSG00000139083|Vega:OTTHUMG00000168538 +2121 EVC MIM:604831|HGNC:HGNC:3497|Ensembl:ENSG00000072840|Vega:OTTHUMG00000090427 +2122 MECOM MIM:165215|HGNC:HGNC:3498|Ensembl:ENSG00000085276|Vega:OTTHUMG00000158596 +2123 EVI2A MIM:158380|HGNC:HGNC:3499|Ensembl:ENSG00000126860|Vega:OTTHUMG00000159306 +2124 EVI2B MIM:158381|HGNC:HGNC:3500|Ensembl:ENSG00000185862|Vega:OTTHUMG00000132869 +2125 EVPL MIM:601590|HGNC:HGNC:3503|Ensembl:ENSG00000167880|Vega:OTTHUMG00000180053 +2128 EVX1 MIM:142996|HGNC:HGNC:3506|Ensembl:ENSG00000106038|Vega:OTTHUMG00000023093 +2130 EWSR1 MIM:133450|HGNC:HGNC:3508|Ensembl:ENSG00000182944|Vega:OTTHUMG00000151107 +2131 EXT1 MIM:608177|HGNC:HGNC:3512|Ensembl:ENSG00000182197|Vega:OTTHUMG00000059718 +2132 EXT2 MIM:608210|HGNC:HGNC:3513|Ensembl:ENSG00000151348|Vega:OTTHUMG00000166498 +2133 EXT3 MIM:600209|HGNC:HGNC:3514 +2134 EXTL1 MIM:601738|HGNC:HGNC:3515|Ensembl:ENSG00000158008|Vega:OTTHUMG00000007509 +2135 EXTL2 MIM:602411|HGNC:HGNC:3516|Ensembl:ENSG00000162694|Vega:OTTHUMG00000011814 +2137 EXTL3 MIM:605744|HGNC:HGNC:3518|Ensembl:ENSG00000012232|Vega:OTTHUMG00000102146 +2138 EYA1 MIM:601653|HGNC:HGNC:3519|Ensembl:ENSG00000104313|Vega:OTTHUMG00000149894 +2139 EYA2 MIM:601654|HGNC:HGNC:3520|Ensembl:ENSG00000064655|Vega:OTTHUMG00000033041 +2140 EYA3 MIM:601655|HGNC:HGNC:3521|Ensembl:ENSG00000158161|Vega:OTTHUMG00000003916 +2141 EYCL1 HGNC:HGNC:3523 +2145 EZH1 MIM:601674|HGNC:HGNC:3526|Ensembl:ENSG00000108799|Vega:OTTHUMG00000180645 +2146 EZH2 MIM:601573|HGNC:HGNC:3527|Ensembl:ENSG00000106462|Vega:OTTHUMG00000158973 +2147 F2 MIM:176930|HGNC:HGNC:3535|Ensembl:ENSG00000180210|Vega:OTTHUMG00000150344 +2149 F2R MIM:187930|HGNC:HGNC:3537|Ensembl:ENSG00000181104|Vega:OTTHUMG00000131299 +2150 F2RL1 MIM:600933|HGNC:HGNC:3538|Ensembl:ENSG00000164251|Vega:OTTHUMG00000102118 +2151 F2RL2 MIM:601919|HGNC:HGNC:3539|Ensembl:ENSG00000164220|Vega:OTTHUMG00000102119 +2152 F3 MIM:134390|HGNC:HGNC:3541|Ensembl:ENSG00000117525|Vega:OTTHUMG00000010716 +2153 F5 MIM:612309|HGNC:HGNC:3542|Ensembl:ENSG00000198734|Vega:OTTHUMG00000034595 +2155 F7 MIM:613878|HGNC:HGNC:3544|Ensembl:ENSG00000057593|Vega:OTTHUMG00000017373 +2156 F7R MIM:134450|HGNC:HGNC:3545 +2157 F8 MIM:300841|HGNC:HGNC:3546|Ensembl:ENSG00000185010|Vega:OTTHUMG00000022688 +2158 F9 MIM:300746|HGNC:HGNC:3551|Ensembl:ENSG00000101981|Vega:OTTHUMG00000022536 +2159 F10 MIM:613872|HGNC:HGNC:3528|Ensembl:ENSG00000126218|Vega:OTTHUMG00000017374 +2160 F11 MIM:264900|HGNC:HGNC:3529|Ensembl:ENSG00000088926|Vega:OTTHUMG00000150311 +2161 F12 MIM:610619|HGNC:HGNC:3530|Ensembl:ENSG00000131187|Vega:OTTHUMG00000163403 +2162 F13A1 MIM:134570|HGNC:HGNC:3531|Ensembl:ENSG00000124491|Vega:OTTHUMG00000014186 +2165 F13B MIM:134580|HGNC:HGNC:3534|Ensembl:ENSG00000143278|Vega:OTTHUMG00000036519 +2166 FAAH MIM:602935|HGNC:HGNC:3553|Ensembl:ENSG00000117480|Vega:OTTHUMG00000007811 +2167 FABP4 MIM:600434|HGNC:HGNC:3559|Ensembl:ENSG00000170323|Vega:OTTHUMG00000164602 +2168 FABP1 MIM:134650|HGNC:HGNC:3555|Ensembl:ENSG00000163586|Vega:OTTHUMG00000130312 +2169 FABP2 MIM:134640|HGNC:HGNC:3556|Ensembl:ENSG00000145384|Vega:OTTHUMG00000132972 +2170 FABP3 MIM:134651|HGNC:HGNC:3557|Ensembl:ENSG00000121769|Vega:OTTHUMG00000003797 +2171 FABP5 MIM:605168|HGNC:HGNC:3560|Ensembl:ENSG00000164687|Vega:OTTHUMG00000134313 +2172 FABP6 MIM:600422|HGNC:HGNC:3561|Ensembl:ENSG00000170231|Vega:OTTHUMG00000130329 +2173 FABP7 MIM:602965|HGNC:HGNC:3562|Ensembl:ENSG00000164434|Vega:OTTHUMG00000015489 +2175 FANCA MIM:607139|HGNC:HGNC:3582|Ensembl:ENSG00000187741|Vega:OTTHUMG00000173049 +2176 FANCC MIM:613899|HGNC:HGNC:3584|Ensembl:ENSG00000158169|Vega:OTTHUMG00000020279 +2177 FANCD2 MIM:613984|HGNC:HGNC:3585|Ensembl:ENSG00000144554|Vega:OTTHUMG00000128670 +2178 FANCE MIM:613976|HGNC:HGNC:3586|Ensembl:ENSG00000112039|Vega:OTTHUMG00000014565 +2180 ACSL1 MIM:152425|HGNC:HGNC:3569|Ensembl:ENSG00000151726|Vega:OTTHUMG00000160547 +2181 ACSL3 MIM:602371|HGNC:HGNC:3570|Ensembl:ENSG00000123983|Vega:OTTHUMG00000133160 +2182 ACSL4 MIM:300157|HGNC:HGNC:3571|Ensembl:ENSG00000068366|Vega:OTTHUMG00000022190 +2184 FAH MIM:613871|HGNC:HGNC:3579|Ensembl:ENSG00000103876|Vega:OTTHUMG00000144187 +2185 PTK2B MIM:601212|HGNC:HGNC:9612|Ensembl:ENSG00000120899|Vega:OTTHUMG00000102082 +2186 BPTF MIM:601819|HGNC:HGNC:3581|Ensembl:ENSG00000171634|Vega:OTTHUMG00000132254 +2187 FANCB MIM:300515|HGNC:HGNC:3583|Ensembl:ENSG00000181544|Vega:OTTHUMG00000021168 +2188 FANCF MIM:613897|HGNC:HGNC:3587|Ensembl:ENSG00000183161|Vega:OTTHUMG00000166070 +2189 FANCG MIM:602956|HGNC:HGNC:3588|Ensembl:ENSG00000221829|Vega:OTTHUMG00000019850 +2191 FAP MIM:600403|HGNC:HGNC:3590|Ensembl:ENSG00000078098|Vega:OTTHUMG00000153890 +2192 FBLN1 MIM:135820|HGNC:HGNC:3600|Ensembl:ENSG00000077942|Vega:OTTHUMG00000151340 +2193 FARSA MIM:602918|HGNC:HGNC:3592|Ensembl:ENSG00000179115|Vega:OTTHUMG00000180569 +2194 FASN MIM:600212|HGNC:HGNC:3594|Ensembl:ENSG00000169710|Vega:OTTHUMG00000178527 +2195 FAT1 MIM:600976|HGNC:HGNC:3595|Ensembl:ENSG00000083857|Vega:OTTHUMG00000160320 +2196 FAT2 MIM:604269|HGNC:HGNC:3596|Ensembl:ENSG00000086570|Vega:OTTHUMG00000130126 +2197 FAU MIM:134690|HGNC:HGNC:3597|Ensembl:ENSG00000149806|Vega:OTTHUMG00000165606 +2199 FBLN2 MIM:135821|HGNC:HGNC:3601|Ensembl:ENSG00000163520|Vega:OTTHUMG00000155437 +2200 FBN1 MIM:134797|HGNC:HGNC:3603|Ensembl:ENSG00000166147|Vega:OTTHUMG00000172218 +2201 FBN2 MIM:612570|HGNC:HGNC:3604|Ensembl:ENSG00000138829|Vega:OTTHUMG00000163082 +2202 EFEMP1 MIM:601548|HGNC:HGNC:3218|Ensembl:ENSG00000115380|Vega:OTTHUMG00000129343 +2203 FBP1 MIM:611570|HGNC:HGNC:3606|Ensembl:ENSG00000165140|Vega:OTTHUMG00000020268 +2204 FCAR MIM:147045|HGNC:HGNC:3608|Ensembl:ENSG00000186431|Vega:OTTHUMG00000065936 +2205 FCER1A MIM:147140|HGNC:HGNC:3609|Ensembl:ENSG00000179639|Vega:OTTHUMG00000037176 +2206 MS4A2 MIM:147138|HGNC:HGNC:7316|Ensembl:ENSG00000149534|Vega:OTTHUMG00000167239 +2207 FCER1G MIM:147139|HGNC:HGNC:3611|Ensembl:ENSG00000158869|Vega:OTTHUMG00000034343 +2208 FCER2 MIM:151445|HGNC:HGNC:3612|Ensembl:ENSG00000104921|Vega:OTTHUMG00000182517 +2209 FCGR1A MIM:146760|HGNC:HGNC:3613|Ensembl:ENSG00000150337|Vega:OTTHUMG00000012089 +2210 FCGR1B MIM:601502|HGNC:HGNC:3614|Ensembl:ENSG00000198019|Vega:OTTHUMG00000040903 +2212 FCGR2A MIM:146790|HGNC:HGNC:3616|Ensembl:ENSG00000143226|Vega:OTTHUMG00000034469 +2213 FCGR2B MIM:604590|HGNC:HGNC:3618|Ensembl:ENSG00000072694|Vega:OTTHUMG00000034470 +2214 FCGR3A MIM:146740|HGNC:HGNC:3619|Ensembl:ENSG00000203747|Vega:OTTHUMG00000034466 +2215 FCGR3B MIM:610665|HGNC:HGNC:3620|Ensembl:ENSG00000162747|Vega:OTTHUMG00000074099 +2216 FDX1P2 HGNC:HGNC:3641 +2217 FCGRT MIM:601437|HGNC:HGNC:3621|Ensembl:ENSG00000104870|Vega:OTTHUMG00000183155 +2218 FKTN MIM:607440|HGNC:HGNC:3622|Ensembl:ENSG00000106692|Vega:OTTHUMG00000020425 +2219 FCN1 MIM:601252|HGNC:HGNC:3623|Ensembl:ENSG00000085265|Vega:OTTHUMG00000020895 +2220 FCN2 MIM:601624|HGNC:HGNC:3624|Ensembl:ENSG00000160339|Vega:OTTHUMG00000020892 +2221 FCP1 MIM:305435|HGNC:HGNC:3627 +2222 FDFT1 MIM:184420|HGNC:HGNC:3629|Ensembl:ENSG00000079459|Vega:OTTHUMG00000090801 +2224 FDPS MIM:134629|HGNC:HGNC:3631|Ensembl:ENSG00000160752|Vega:OTTHUMG00000013909 +2227 FDPSP3 HGNC:HGNC:3634 +2228 FDPSP4 HGNC:HGNC:3635 +2229 FDPSP5 HGNC:HGNC:3636 +2230 FDX1 MIM:103260|HGNC:HGNC:3638|Ensembl:ENSG00000137714|Vega:OTTHUMG00000166589 +2231 FDX1P1 HGNC:HGNC:3640 +2232 FDXR MIM:103270|HGNC:HGNC:3642|Ensembl:ENSG00000161513|Vega:OTTHUMG00000179026 +2233 FEB1 MIM:121210|HGNC:HGNC:3643 +2234 FEB2 MIM:602477|HGNC:HGNC:3644 +2235 FECH MIM:612386|HGNC:HGNC:3647|Ensembl:ENSG00000066926|Vega:OTTHUMG00000132740 +2236 FECHP1 HGNC:HGNC:3648 +2237 FEN1 MIM:600393|HGNC:HGNC:3650|Ensembl:ENSG00000168496|Vega:OTTHUMG00000168162 +2239 GPC4 MIM:300168|HGNC:HGNC:4452|Ensembl:ENSG00000076716|Vega:OTTHUMG00000022434 +2241 FER MIM:176942|HGNC:HGNC:3655|Ensembl:ENSG00000151422|Vega:OTTHUMG00000128751 +2242 FES MIM:190030|HGNC:HGNC:3657|Ensembl:ENSG00000182511|Vega:OTTHUMG00000044456 +2243 FGA MIM:134820|HGNC:HGNC:3661|Ensembl:ENSG00000171560|Vega:OTTHUMG00000150330 +2244 FGB MIM:134830|HGNC:HGNC:3662|Ensembl:ENSG00000171564|Vega:OTTHUMG00000150331 +2245 FGD1 MIM:300546|HGNC:HGNC:3663|Ensembl:ENSG00000102302|Vega:OTTHUMG00000021627 +2246 FGF1 MIM:131220|HGNC:HGNC:3665|Ensembl:ENSG00000113578|Vega:OTTHUMG00000059703 +2247 FGF2 MIM:134920|HGNC:HGNC:3676|Ensembl:ENSG00000138685|Vega:OTTHUMG00000039506 +2248 FGF3 MIM:164950|HGNC:HGNC:3681|Ensembl:ENSG00000186895|Vega:OTTHUMG00000167888 +2249 FGF4 MIM:164980|HGNC:HGNC:3682|Ensembl:ENSG00000075388|Vega:OTTHUMG00000167887 +2250 FGF5 MIM:165190|HGNC:HGNC:3683|Ensembl:ENSG00000138675|Vega:OTTHUMG00000130288 +2251 FGF6 MIM:134921|HGNC:HGNC:3684|Ensembl:ENSG00000111241|Vega:OTTHUMG00000168242 +2252 FGF7 MIM:148180|HGNC:HGNC:3685|Ensembl:ENSG00000140285|Vega:OTTHUMG00000131517 +2253 FGF8 MIM:600483|HGNC:HGNC:3686|Ensembl:ENSG00000107831|Vega:OTTHUMG00000018940 +2254 FGF9 MIM:600921|HGNC:HGNC:3687|Ensembl:ENSG00000102678|Vega:OTTHUMG00000017412 +2255 FGF10 MIM:602115|HGNC:HGNC:3666|Ensembl:ENSG00000070193|Vega:OTTHUMG00000131153 +2256 FGF11 MIM:601514|HGNC:HGNC:3667|Ensembl:ENSG00000161958|Vega:OTTHUMG00000108136 +2257 FGF12 MIM:601513|HGNC:HGNC:3668|Ensembl:ENSG00000114279|Vega:OTTHUMG00000156132 +2258 FGF13 MIM:300070|HGNC:HGNC:3670|Ensembl:ENSG00000129682|Vega:OTTHUMG00000022532 +2259 FGF14 MIM:601515|HGNC:HGNC:3671|Ensembl:ENSG00000102466|Vega:OTTHUMG00000017303 +2260 FGFR1 MIM:136350|HGNC:HGNC:3688|Ensembl:ENSG00000077782|Vega:OTTHUMG00000147366 +2261 FGFR3 MIM:134934|HGNC:HGNC:3690|Ensembl:ENSG00000068078|Vega:OTTHUMG00000121148 +2262 GPC5 MIM:602446|HGNC:HGNC:4453|Ensembl:ENSG00000179399|Vega:OTTHUMG00000017200 +2263 FGFR2 MIM:176943|HGNC:HGNC:3689|Ensembl:ENSG00000066468|Vega:OTTHUMG00000019175 +2264 FGFR4 MIM:134935|HGNC:HGNC:3691|Ensembl:ENSG00000160867|Vega:OTTHUMG00000151523 +2266 FGG MIM:134850|HGNC:HGNC:3694|Ensembl:ENSG00000171557|Vega:OTTHUMG00000150329 +2267 FGL1 MIM:605776|HGNC:HGNC:3695|Ensembl:ENSG00000104760|Vega:OTTHUMG00000096989 +2268 FGR MIM:164940|HGNC:HGNC:3697|Ensembl:ENSG00000000938|Vega:OTTHUMG00000003516 +2270 FGS2 MIM:300321|HGNC:HGNC:3699 +2271 FH MIM:136850|HGNC:HGNC:3700|Ensembl:ENSG00000091483|Vega:OTTHUMG00000039597 +2272 FHIT MIM:601153|HGNC:HGNC:3701|Ensembl:ENSG00000189283|Vega:OTTHUMG00000158591 +2273 FHL1 MIM:300163|HGNC:HGNC:3702|Ensembl:ENSG00000022267|Vega:OTTHUMG00000022504 +2274 FHL2 MIM:602633|HGNC:HGNC:3703|Ensembl:ENSG00000115641|Vega:OTTHUMG00000153120 +2275 FHL3 MIM:602790|HGNC:HGNC:3704|Ensembl:ENSG00000183386|Vega:OTTHUMG00000004434 +2277 VEGFD MIM:300091|HGNC:HGNC:3708|Ensembl:ENSG00000165197|Vega:OTTHUMG00000021175 +2278 FIM1 - +2279 FIM3 - +2280 FKBP1A MIM:186945|HGNC:HGNC:3711|Ensembl:ENSG00000088832|Vega:OTTHUMG00000031666 +2281 FKBP1B MIM:600620|HGNC:HGNC:3712|Ensembl:ENSG00000119782|Vega:OTTHUMG00000151889 +2282 FKBP1AP1 HGNC:HGNC:3714 +2283 FKBP1AP2 HGNC:HGNC:3715 +2284 FKBP1AP3 HGNC:HGNC:3716 +2285 FKBP1AP4 HGNC:HGNC:3717 +2286 FKBP2 MIM:186946|HGNC:HGNC:3718|Ensembl:ENSG00000173486|Vega:OTTHUMG00000167814 +2287 FKBP3 MIM:186947|HGNC:HGNC:3719|Ensembl:ENSG00000100442|Vega:OTTHUMG00000140267 +2288 FKBP4 MIM:600611|HGNC:HGNC:3720|Ensembl:ENSG00000004478|Vega:OTTHUMG00000090429 +2289 FKBP5 MIM:602623|HGNC:HGNC:3721|Ensembl:ENSG00000096060|Vega:OTTHUMG00000014576 +2290 FOXG1 MIM:164874|HGNC:HGNC:3811|Ensembl:ENSG00000176165|Vega:OTTHUMG00000140187 +2294 FOXF1 MIM:601089|HGNC:HGNC:3809|Ensembl:ENSG00000103241|Vega:OTTHUMG00000137651 +2295 FOXF2 MIM:603250|HGNC:HGNC:3810|Ensembl:ENSG00000137273|Vega:OTTHUMG00000016243 +2296 FOXC1 MIM:601090|HGNC:HGNC:3800|Ensembl:ENSG00000054598|Vega:OTTHUMG00000016182 +2297 FOXD1 MIM:601091|HGNC:HGNC:3802|Ensembl:ENSG00000251493|Vega:OTTHUMG00000162495 +2298 FOXD4 MIM:601092|HGNC:HGNC:3805|Ensembl:ENSG00000170122|Vega:OTTHUMG00000021015 +2299 FOXI1 MIM:601093|HGNC:HGNC:3815|Ensembl:ENSG00000168269|Vega:OTTHUMG00000130436 +2300 FOXL1 MIM:603252|HGNC:HGNC:3817|Ensembl:ENSG00000176678|Vega:OTTHUMG00000137653 +2301 FOXE3 MIM:601094|HGNC:HGNC:3808|Ensembl:ENSG00000186790|Vega:OTTHUMG00000007954 +2302 FOXJ1 MIM:602291|HGNC:HGNC:3816|Ensembl:ENSG00000129654|Vega:OTTHUMG00000180120 +2303 FOXC2 MIM:602402|HGNC:HGNC:3801|Ensembl:ENSG00000176692|Vega:OTTHUMG00000137652 +2304 FOXE1 MIM:602617|HGNC:HGNC:3806|Ensembl:ENSG00000178919|Vega:OTTHUMG00000020333 +2305 FOXM1 MIM:602341|HGNC:HGNC:3818|Ensembl:ENSG00000111206|Vega:OTTHUMG00000168118 +2306 FOXD2 MIM:602211|HGNC:HGNC:3803|Ensembl:ENSG00000186564|Vega:OTTHUMG00000007950 +2307 FOXS1 MIM:602939|HGNC:HGNC:3735|Ensembl:ENSG00000179772|Vega:OTTHUMG00000032183 +2308 FOXO1 MIM:136533|HGNC:HGNC:3819|Ensembl:ENSG00000150907|Vega:OTTHUMG00000016775 +2309 FOXO3 MIM:602681|HGNC:HGNC:3821|Ensembl:ENSG00000118689|Vega:OTTHUMG00000015327 +2310 FOXO3B HGNC:HGNC:3822 +2311 FOXO1B HGNC:HGNC:3820 +2312 FLG MIM:135940|HGNC:HGNC:3748|Ensembl:ENSG00000143631|Vega:OTTHUMG00000012202 +2313 FLI1 MIM:193067|HGNC:HGNC:3749|Ensembl:ENSG00000151702|Vega:OTTHUMG00000165792 +2314 FLII MIM:600362|HGNC:HGNC:3750|Ensembl:ENSG00000177731|Vega:OTTHUMG00000059389 +2315 MLANA MIM:605513|HGNC:HGNC:7124|Ensembl:ENSG00000120215|Vega:OTTHUMG00000019510 +2316 FLNA MIM:300017|HGNC:HGNC:3754|Ensembl:ENSG00000196924|Vega:OTTHUMG00000022712 +2317 FLNB MIM:603381|HGNC:HGNC:3755|Ensembl:ENSG00000136068|Vega:OTTHUMG00000159158 +2318 FLNC MIM:102565|HGNC:HGNC:3756|Ensembl:ENSG00000128591|Vega:OTTHUMG00000023627 +2319 FLOT2 MIM:131560|HGNC:HGNC:3758|Ensembl:ENSG00000132589|Vega:OTTHUMG00000132674 +2321 FLT1 MIM:165070|HGNC:HGNC:3763|Ensembl:ENSG00000102755|Vega:OTTHUMG00000016648 +2322 FLT3 MIM:136351|HGNC:HGNC:3765|Ensembl:ENSG00000122025|Vega:OTTHUMG00000016646 +2323 FLT3LG MIM:600007|HGNC:HGNC:3766|Ensembl:ENSG00000090554|Vega:OTTHUMG00000186490 +2324 FLT4 MIM:136352|HGNC:HGNC:3767|Ensembl:ENSG00000037280|Vega:OTTHUMG00000130931 +2326 FMO1 MIM:136130|HGNC:HGNC:3769|Ensembl:ENSG00000010932|Vega:OTTHUMG00000035502 +2327 FMO2 MIM:603955|HGNC:HGNC:3770|Ensembl:ENSG00000094963|Vega:OTTHUMG00000035504 +2328 FMO3 MIM:136132|HGNC:HGNC:3771|Ensembl:ENSG00000007933|Vega:OTTHUMG00000035505 +2329 FMO4 MIM:136131|HGNC:HGNC:3772|Ensembl:ENSG00000076258|Vega:OTTHUMG00000035506 +2330 FMO5 MIM:603957|HGNC:HGNC:3773|Ensembl:ENSG00000131781|Vega:OTTHUMG00000014607 +2331 FMOD MIM:600245|HGNC:HGNC:3774|Ensembl:ENSG00000122176|Vega:OTTHUMG00000035910 +2332 FMR1 MIM:309550|HGNC:HGNC:3775|Ensembl:ENSG00000102081|Vega:OTTHUMG00000022606 +2334 AFF2 MIM:300806|HGNC:HGNC:3776|Ensembl:ENSG00000155966|Vega:OTTHUMG00000022613 +2335 FN1 MIM:135600|HGNC:HGNC:3778|Ensembl:ENSG00000115414|Vega:OTTHUMG00000133054 +2339 FNTA MIM:134635|HGNC:HGNC:3782|Ensembl:ENSG00000168522|Vega:OTTHUMG00000165279 +2341 FNTAP2 HGNC:HGNC:3784 +2342 FNTB MIM:134636|HGNC:HGNC:3785|Ensembl:ENSG00000257365|Vega:OTTHUMG00000142811 +2346 FOLH1 MIM:600934|HGNC:HGNC:3788|Ensembl:ENSG00000086205|Vega:OTTHUMG00000166625 +2348 FOLR1 MIM:136430|HGNC:HGNC:3791|Ensembl:ENSG00000110195|Vega:OTTHUMG00000167876 +2350 FOLR2 MIM:136425|HGNC:HGNC:3793|Ensembl:ENSG00000165457|Vega:OTTHUMG00000150394 +2352 FOLR3 MIM:602469|HGNC:HGNC:3795|Ensembl:ENSG00000110203|Vega:OTTHUMG00000167870 +2353 FOS MIM:164810|HGNC:HGNC:3796|Ensembl:ENSG00000170345|Vega:OTTHUMG00000171774 +2354 FOSB MIM:164772|HGNC:HGNC:3797|Ensembl:ENSG00000125740|Vega:OTTHUMG00000182122 +2355 FOSL2 MIM:601575|HGNC:HGNC:3798|Ensembl:ENSG00000075426|Vega:OTTHUMG00000097832 +2356 FPGS MIM:136510|HGNC:HGNC:3824|Ensembl:ENSG00000136877|Vega:OTTHUMG00000020716 +2357 FPR1 MIM:136537|HGNC:HGNC:3826|Ensembl:ENSG00000171051|Vega:OTTHUMG00000183500 +2358 FPR2 MIM:136538|HGNC:HGNC:3827|Ensembl:ENSG00000171049|Vega:OTTHUMG00000183501 +2359 FPR3 MIM:136539|HGNC:HGNC:3828|Ensembl:ENSG00000187474|Vega:OTTHUMG00000183502 +2360 FRA1A HGNC:HGNC:3868 +2361 FRA1B HGNC:HGNC:3869 +2362 FRA1C HGNC:HGNC:3870 +2363 FRA1D HGNC:HGNC:3871 +2364 FRA1E HGNC:HGNC:3872 +2365 FRA1F HGNC:HGNC:3873 +2366 FRA1G HGNC:HGNC:3874 +2367 FRA1H HGNC:HGNC:3875 +2368 FRA1I HGNC:HGNC:3876 +2369 FRA1J HGNC:HGNC:3877 +2370 FRA1K HGNC:HGNC:3878 +2371 FRA1L HGNC:HGNC:3879 +2372 FRA1M HGNC:HGNC:3880 +2373 FRA2A MIM:136610|HGNC:HGNC:3885 +2374 FRA2B HGNC:HGNC:3886 +2375 FRA2C HGNC:HGNC:3887 +2376 FRA2D HGNC:HGNC:3888 +2377 FRA2E HGNC:HGNC:3889 +2378 FRA2F HGNC:HGNC:3890 +2379 FRA2G HGNC:HGNC:3891 +2380 FRA2H HGNC:HGNC:3892 +2381 FRA2I HGNC:HGNC:3893 +2382 FRA2J HGNC:HGNC:3894 +2383 FRA2K HGNC:HGNC:3895 +2384 FRA3A HGNC:HGNC:3896 +2386 FRA3C HGNC:HGNC:3898 +2387 FRA3D HGNC:HGNC:3899 +2388 FRA4A HGNC:HGNC:3900 +2389 FRA4B HGNC:HGNC:3901 +2390 FRA4C HGNC:HGNC:3902 +2391 FRA4D HGNC:HGNC:3903 +2393 FRA5A HGNC:HGNC:3905 +2394 FRA5B HGNC:HGNC:3906 +2395 FXN MIM:606829|HGNC:HGNC:3951|Ensembl:ENSG00000165060|Vega:OTTHUMG00000019977 +2396 FRA5C HGNC:HGNC:3907 +2397 FRA5D HGNC:HGNC:3908 +2398 FRA5E HGNC:HGNC:3909 +2399 FRA5F HGNC:HGNC:3910 +2400 FRA5G HGNC:HGNC:3911 +2401 FRA6A HGNC:HGNC:3912 +2402 FRA6B HGNC:HGNC:3913 +2403 FRA6C HGNC:HGNC:3914 +2404 FRA6D HGNC:HGNC:3915 +2405 FRA6E HGNC:HGNC:3916 +2406 FRA6F HGNC:HGNC:3917 +2407 FRA6G HGNC:HGNC:3918 +2408 FRA7A HGNC:HGNC:3919 +2409 FRA7B HGNC:HGNC:3920 +2410 FRA7C HGNC:HGNC:3921 +2411 FRA7D HGNC:HGNC:3922 +2412 FRA7E HGNC:HGNC:3923 +2413 FRA7F HGNC:HGNC:3924 +2414 FRA7G HGNC:HGNC:3925 +2415 FRA7H HGNC:HGNC:3926 +2416 FRA7I HGNC:HGNC:3927 +2417 FRA7J HGNC:HGNC:3928 +2418 FRA8A HGNC:HGNC:3929 +2419 FRA8B HGNC:HGNC:3930 +2420 FRDA2 MIM:601992|HGNC:HGNC:3952 +2421 FRA8C HGNC:HGNC:3931 +2422 FRA8D HGNC:HGNC:3932 +2423 FRA8E HGNC:HGNC:3933 +2425 FRA9A HGNC:HGNC:3935 +2426 FRA9B MIM:136640|HGNC:HGNC:3936 +2427 FRA9C HGNC:HGNC:3937 +2428 FRA9D HGNC:HGNC:3938 +2429 FRA9E HGNC:HGNC:3939 +2430 FRA9F HGNC:HGNC:3940 +2431 FRA10A MIM:136620|HGNC:HGNC:3829 +2432 FRA10B HGNC:HGNC:3830 +2433 FRA10C HGNC:HGNC:3831 +2434 FRA10D HGNC:HGNC:3832 +2435 FRA10E HGNC:HGNC:3833 +2436 FRA10F HGNC:HGNC:3834 +2437 FRA10G HGNC:HGNC:3835 +2438 FRA11A HGNC:HGNC:3836 +2440 FRA11C HGNC:HGNC:3838 +2441 FRA11D HGNC:HGNC:3839 +2442 FRA11E HGNC:HGNC:3840 +2443 FRA11F HGNC:HGNC:3841 +2444 FRK MIM:606573|HGNC:HGNC:3955|Ensembl:ENSG00000111816|Vega:OTTHUMG00000015424 +2445 FRA11G HGNC:HGNC:3842 +2446 FRA11H HGNC:HGNC:3843 +2447 FRA11I HGNC:HGNC:3844 +2448 FRA12A HGNC:HGNC:3845 +2449 FRA12B HGNC:HGNC:3846 +2450 FRA12C HGNC:HGNC:3847 +2451 FRA12D HGNC:HGNC:3848 +2452 FRA12E HGNC:HGNC:3849 +2453 FRA13A HGNC:HGNC:3850 +2454 FRA13B HGNC:HGNC:3851 +2455 FRA13C HGNC:HGNC:3852 +2456 FRA13D HGNC:HGNC:3853 +2457 FRA14B HGNC:HGNC:3854 +2458 FRA14C HGNC:HGNC:3855 +2459 FRA15A HGNC:HGNC:3856 +2460 FRA16A HGNC:HGNC:3857 +2461 FRA16B MIM:136580|HGNC:HGNC:3858 +2462 FRA16C HGNC:HGNC:3859 +2463 FRA16D HGNC:HGNC:3860 +2464 FRA16E MIM:136570|HGNC:HGNC:3861 +2465 FRA17A MIM:136660|HGNC:HGNC:3862 +2466 FRA17B HGNC:HGNC:3863 +2467 FRA18A HGNC:HGNC:3864 +2468 FRA18B HGNC:HGNC:3865 +2469 FRA19A HGNC:HGNC:3866 +2470 FRA19B HGNC:HGNC:3867 +2471 FRA20A MIM:136590|HGNC:HGNC:3881 +2472 FRA20B HGNC:HGNC:3882 +2473 FRA22A HGNC:HGNC:3883 +2474 FRA22B HGNC:HGNC:3884 +2475 MTOR MIM:601231|HGNC:HGNC:3942|Ensembl:ENSG00000198793|Vega:OTTHUMG00000002001 +2477 FRAXA HGNC:HGNC:3945 +2478 FRAXB HGNC:HGNC:3946 +2479 FRAXC HGNC:HGNC:3947 +2480 FRAXD HGNC:HGNC:3948 +2481 FRAXE HGNC:HGNC:3949 +2483 FRG1 MIM:601278|HGNC:HGNC:3954|Ensembl:ENSG00000109536|Vega:OTTHUMG00000160202 +2487 FRZB MIM:605083|HGNC:HGNC:3959|Ensembl:ENSG00000162998|Vega:OTTHUMG00000132597 +2488 FSHB MIM:136530|HGNC:HGNC:3964|Ensembl:ENSG00000131808|Vega:OTTHUMG00000166146 +2489 FSHMD1A MIM:158900|HGNC:HGNC:3966 +2490 FSHMD1B MIM:158901|HGNC:HGNC:3967 +2491 CENPI MIM:300065|HGNC:HGNC:3968|Ensembl:ENSG00000102384|Vega:OTTHUMG00000022018 +2492 FSHR MIM:136435|HGNC:HGNC:3969|Ensembl:ENSG00000170820|Vega:OTTHUMG00000129259 +2494 NR5A2 MIM:604453|HGNC:HGNC:7984|Ensembl:ENSG00000116833|Vega:OTTHUMG00000035635 +2495 FTH1 MIM:134770|HGNC:HGNC:3976|Ensembl:ENSG00000167996|Vega:OTTHUMG00000166217 +2496 FTH1P1 HGNC:HGNC:3979 +2497 FTH1P2 HGNC:HGNC:3989 +2498 FTH1P3 HGNC:HGNC:3990 +2499 FTH1P4 HGNC:HGNC:3991 +2500 FTH1P7 HGNC:HGNC:3994 +2501 FTH1P8 HGNC:HGNC:3995 +2502 FTH1P10 HGNC:HGNC:3980 +2503 FTH1P11 HGNC:HGNC:3981 +2504 FTH1P12 HGNC:HGNC:3982 +2507 FTH1P15 HGNC:HGNC:3985 +2508 FTH1P16 HGNC:HGNC:3986 +2509 FTH1P5 HGNC:HGNC:3996 +2510 FTH1P21 HGNC:HGNC:3997 +2512 FTL MIM:134790|HGNC:HGNC:3999|Ensembl:ENSG00000087086|Vega:OTTHUMG00000183332 +2515 ADAM2 MIM:601533|HGNC:HGNC:198|Ensembl:ENSG00000104755|Vega:OTTHUMG00000164041 +2516 NR5A1 MIM:184757|HGNC:HGNC:7983|Ensembl:ENSG00000136931|Vega:OTTHUMG00000020655 +2517 FUCA1 MIM:612280|HGNC:HGNC:4006|Ensembl:ENSG00000179163|Vega:OTTHUMG00000002965 +2518 FUCA1P1 HGNC:HGNC:4007 +2519 FUCA2 MIM:136820|HGNC:HGNC:4008|Ensembl:ENSG00000001036|Vega:OTTHUMG00000015728 +2520 GAST MIM:137250|HGNC:HGNC:4164|Ensembl:ENSG00000184502|Vega:OTTHUMG00000133496 +2521 FUS MIM:137070|HGNC:HGNC:4010|Ensembl:ENSG00000089280|Vega:OTTHUMG00000132395 +2522 FUSE MIM:174750|HGNC:HGNC:4011 +2523 FUT1 MIM:211100|HGNC:HGNC:4012|Ensembl:ENSG00000174951|Vega:OTTHUMG00000183325 +2524 FUT2 MIM:182100|HGNC:HGNC:4013|Ensembl:ENSG00000176920|Vega:OTTHUMG00000164427 +2525 FUT3 MIM:111100|HGNC:HGNC:4014|Ensembl:ENSG00000171124|Vega:OTTHUMG00000180614 +2526 FUT4 MIM:104230|HGNC:HGNC:4015|Ensembl:ENSG00000196371|Vega:OTTHUMG00000167795 +2527 FUT5 MIM:136835|HGNC:HGNC:4016|Ensembl:ENSG00000130383|Vega:OTTHUMG00000180616 +2528 FUT6 MIM:136836|HGNC:HGNC:4017|Ensembl:ENSG00000156413|Vega:OTTHUMG00000167335 +2529 FUT7 MIM:602030|HGNC:HGNC:4018|Ensembl:ENSG00000180549|Vega:OTTHUMG00000020964 +2530 FUT8 MIM:602589|HGNC:HGNC:4019|Ensembl:ENSG00000033170|Vega:OTTHUMG00000142818 +2531 KDSR MIM:136440|HGNC:HGNC:4021|Ensembl:ENSG00000119537|Vega:OTTHUMG00000132792 +2532 ACKR1 MIM:613665|HGNC:HGNC:4035|Ensembl:ENSG00000213088|Vega:OTTHUMG00000037182 +2533 FYB1 MIM:602731|HGNC:HGNC:4036|Ensembl:ENSG00000082074|Vega:OTTHUMG00000162071 +2534 FYN MIM:137025|HGNC:HGNC:4037|Ensembl:ENSG00000010810|Vega:OTTHUMG00000016305 +2535 FZD2 MIM:600667|HGNC:HGNC:4040|Ensembl:ENSG00000180340|Vega:OTTHUMG00000181819 +2537 IFI6 MIM:147572|HGNC:HGNC:4054|Ensembl:ENSG00000126709|Vega:OTTHUMG00000003518 +2538 G6PC MIM:613742|HGNC:HGNC:4056|Ensembl:ENSG00000131482|Vega:OTTHUMG00000180657 +2539 G6PD MIM:305900|HGNC:HGNC:4057|Ensembl:ENSG00000160211|Vega:OTTHUMG00000024237 +2541 G6PR HGNC:HGNC:4059 +2542 SLC37A4 MIM:602671|HGNC:HGNC:4061|Ensembl:ENSG00000137700 +2543 GAGE1 MIM:300594|HGNC:HGNC:4098|Ensembl:ENSG00000205777|Vega:OTTHUMG00000024150 +2547 XRCC6 MIM:152690|HGNC:HGNC:4055|Ensembl:ENSG00000196419|Vega:OTTHUMG00000151190 +2548 GAA MIM:606800|HGNC:HGNC:4065|Ensembl:ENSG00000171298|Vega:OTTHUMG00000177537 +2549 GAB1 MIM:604439|HGNC:HGNC:4066|Ensembl:ENSG00000109458|Vega:OTTHUMG00000161432 +2550 GABBR1 MIM:603540|HGNC:HGNC:4070|Ensembl:ENSG00000204681|Vega:OTTHUMG00000031095 +2551 GABPA MIM:600609|HGNC:HGNC:4071|Ensembl:ENSG00000154727|Vega:OTTHUMG00000078443 +2553 GABPB1 MIM:600610|HGNC:HGNC:4074|Ensembl:ENSG00000104064|Vega:OTTHUMG00000131642 +2554 GABRA1 MIM:137160|HGNC:HGNC:4075|Ensembl:ENSG00000022355|Vega:OTTHUMG00000163586 +2555 GABRA2 MIM:137140|HGNC:HGNC:4076|Ensembl:ENSG00000151834|Vega:OTTHUMG00000044266 +2556 GABRA3 MIM:305660|HGNC:HGNC:4077|Ensembl:ENSG00000011677|Vega:OTTHUMG00000024183 +2557 GABRA4 MIM:137141|HGNC:HGNC:4078|Ensembl:ENSG00000109158|Vega:OTTHUMG00000099431 +2558 GABRA5 MIM:137142|HGNC:HGNC:4079|Ensembl:ENSG00000186297|Vega:OTTHUMG00000171824 +2559 GABRA6 MIM:137143|HGNC:HGNC:4080|Ensembl:ENSG00000145863|Vega:OTTHUMG00000130351 +2560 GABRB1 MIM:137190|HGNC:HGNC:4081|Ensembl:ENSG00000163288|Vega:OTTHUMG00000044269 +2561 GABRB2 MIM:600232|HGNC:HGNC:4082|Ensembl:ENSG00000145864|Vega:OTTHUMG00000130349 +2562 GABRB3 MIM:137192|HGNC:HGNC:4083|Ensembl:ENSG00000166206|Vega:OTTHUMG00000129231 +2563 GABRD MIM:137163|HGNC:HGNC:4084|Ensembl:ENSG00000187730|Vega:OTTHUMG00000041064 +2564 GABRE MIM:300093|HGNC:HGNC:4085|Ensembl:ENSG00000102287|Vega:OTTHUMG00000024176 +2565 GABRG1 MIM:137166|HGNC:HGNC:4086|Ensembl:ENSG00000163285|Vega:OTTHUMG00000128609 +2566 GABRG2 MIM:137164|HGNC:HGNC:4087|Ensembl:ENSG00000113327|Vega:OTTHUMG00000130350 +2567 GABRG3 MIM:600233|HGNC:HGNC:4088|Ensembl:ENSG00000182256|Vega:OTTHUMG00000044462 +2568 GABRP MIM:602729|HGNC:HGNC:4089|Ensembl:ENSG00000094755|Vega:OTTHUMG00000130443 +2569 GABRR1 MIM:137161|HGNC:HGNC:4090|Ensembl:ENSG00000146276|Vega:OTTHUMG00000015195 +2570 GABRR2 MIM:137162|HGNC:HGNC:4091|Ensembl:ENSG00000111886|Vega:OTTHUMG00000015198 +2571 GAD1 MIM:605363|HGNC:HGNC:4092|Ensembl:ENSG00000128683|Vega:OTTHUMG00000044175 +2572 GAD2 MIM:138275|HGNC:HGNC:4093|Ensembl:ENSG00000136750|Vega:OTTHUMG00000017836 +2574 GAGE2C MIM:300595|HGNC:HGNC:31958 +2576 GAGE4 MIM:300597|HGNC:HGNC:4101 +2577 GAGE5 MIM:300598|HGNC:HGNC:4102 +2578 GAGE6 MIM:300599|HGNC:HGNC:4103 +2579 GAGE7 MIM:300601|HGNC:HGNC:4104 +2580 GAK MIM:602052|HGNC:HGNC:4113|Ensembl:ENSG00000178950|Vega:OTTHUMG00000088301 +2581 GALC MIM:606890|HGNC:HGNC:4115|Ensembl:ENSG00000054983|Vega:OTTHUMG00000028646 +2582 GALE MIM:606953|HGNC:HGNC:4116|Ensembl:ENSG00000117308|Vega:OTTHUMG00000002958 +2583 B4GALNT1 MIM:601873|HGNC:HGNC:4117|Ensembl:ENSG00000135454|Vega:OTTHUMG00000170190 +2584 GALK1 MIM:604313|HGNC:HGNC:4118|Ensembl:ENSG00000108479|Vega:OTTHUMG00000179832 +2585 GALK2 MIM:137028|HGNC:HGNC:4119|Ensembl:ENSG00000156958|Vega:OTTHUMG00000172325 +2587 GALR1 MIM:600377|HGNC:HGNC:4132|Ensembl:ENSG00000166573|Vega:OTTHUMG00000132875 +2588 GALNS MIM:612222|HGNC:HGNC:4122|Ensembl:ENSG00000141012|Vega:OTTHUMG00000137862 +2589 GALNT1 MIM:602273|HGNC:HGNC:4123|Ensembl:ENSG00000141429|Vega:OTTHUMG00000132567 +2590 GALNT2 MIM:602274|HGNC:HGNC:4124|Ensembl:ENSG00000143641|Vega:OTTHUMG00000037771 +2591 GALNT3 MIM:601756|HGNC:HGNC:4125|Ensembl:ENSG00000115339|Vega:OTTHUMG00000132157 +2592 GALT MIM:606999|HGNC:HGNC:4135|Ensembl:ENSG00000213930|Vega:OTTHUMG00000019836 +2593 GAMT MIM:601240|HGNC:HGNC:4136|Ensembl:ENSG00000130005|Vega:OTTHUMG00000180095 +2595 GANC MIM:104180|HGNC:HGNC:4139|Ensembl:ENSG00000214013|Vega:OTTHUMG00000130487 +2596 GAP43 MIM:162060|HGNC:HGNC:4140|Ensembl:ENSG00000172020|Vega:OTTHUMG00000133758 +2597 GAPDH MIM:138400|HGNC:HGNC:4141|Ensembl:ENSG00000111640|Vega:OTTHUMG00000137379 +2601 GAPDHP60 HGNC:HGNC:4153 +2609 GAPDHP67 HGNC:HGNC:4145 +2611 GAPDHP69 HGNC:HGNC:4147 +2613 GAPDHP71 HGNC:HGNC:4149 +2615 LRRC32 MIM:137207|HGNC:HGNC:4161|Ensembl:ENSG00000137507|Vega:OTTHUMG00000133687 +2616 GAPDHP1 HGNC:HGNC:4159 +2617 GARS MIM:600287|HGNC:HGNC:4162|Ensembl:ENSG00000106105|Vega:OTTHUMG00000152769 +2618 GART MIM:138440|HGNC:HGNC:4163|Ensembl:ENSG00000159131|Vega:OTTHUMG00000065628 +2619 GAS1 MIM:139185|HGNC:HGNC:4165|Ensembl:ENSG00000180447|Vega:OTTHUMG00000020141 +2620 GAS2 MIM:602835|HGNC:HGNC:4167|Ensembl:ENSG00000148935|Vega:OTTHUMG00000166071 +2621 GAS6 MIM:600441|HGNC:HGNC:4168|Ensembl:ENSG00000183087|Vega:OTTHUMG00000017395 +2622 GAS8 MIM:605178|HGNC:HGNC:4166|Ensembl:ENSG00000141013|Vega:OTTHUMG00000138988 +2623 GATA1 MIM:305371|HGNC:HGNC:4170|Ensembl:ENSG00000102145|Vega:OTTHUMG00000021504 +2624 GATA2 MIM:137295|HGNC:HGNC:4171|Ensembl:ENSG00000179348|Vega:OTTHUMG00000159689 +2625 GATA3 MIM:131320|HGNC:HGNC:4172|Ensembl:ENSG00000107485|Vega:OTTHUMG00000017640 +2626 GATA4 MIM:600576|HGNC:HGNC:4173|Ensembl:ENSG00000136574|Vega:OTTHUMG00000090800 +2627 GATA6 MIM:601656|HGNC:HGNC:4174|Ensembl:ENSG00000141448|Vega:OTTHUMG00000131767 +2628 GATM MIM:602360|HGNC:HGNC:4175|Ensembl:ENSG00000171766|Vega:OTTHUMG00000131427 +2629 GBA MIM:606463|HGNC:HGNC:4177|Ensembl:ENSG00000177628|Vega:OTTHUMG00000035841 +2630 GBAP1 HGNC:HGNC:4178|Ensembl:ENSG00000160766 +2631 NIPSNAP2 MIM:603004|HGNC:HGNC:4179|Ensembl:ENSG00000146729|Vega:OTTHUMG00000022932 +2632 GBE1 MIM:607839|HGNC:HGNC:4180|Ensembl:ENSG00000114480|Vega:OTTHUMG00000158978 +2633 GBP1 MIM:600411|HGNC:HGNC:4182|Ensembl:ENSG00000117228|Vega:OTTHUMG00000010614 +2634 GBP2 MIM:600412|HGNC:HGNC:4183|Ensembl:ENSG00000162645|Vega:OTTHUMG00000010662 +2635 GBP3 MIM:600413|HGNC:HGNC:4184|Ensembl:ENSG00000117226|Vega:OTTHUMG00000010616 +2636 GBX1 MIM:603354|HGNC:HGNC:4185|Ensembl:ENSG00000164900|Vega:OTTHUMG00000158751 +2637 GBX2 MIM:601135|HGNC:HGNC:4186|Ensembl:ENSG00000168505|Vega:OTTHUMG00000133294 +2638 GC MIM:139200|HGNC:HGNC:4187|Ensembl:ENSG00000145321|Vega:OTTHUMG00000129915 +2639 GCDH MIM:608801|HGNC:HGNC:4189|Ensembl:ENSG00000105607|Vega:OTTHUMG00000180561 +2641 GCG MIM:138030|HGNC:HGNC:4191|Ensembl:ENSG00000115263|Vega:OTTHUMG00000153892 +2642 GCGR MIM:138033|HGNC:HGNC:4192|Ensembl:ENSG00000215644|Vega:OTTHUMG00000177914 +2643 GCH1 MIM:600225|HGNC:HGNC:4193|Ensembl:ENSG00000131979|Vega:OTTHUMG00000029754 +2644 GCHFR MIM:602437|HGNC:HGNC:4194|Ensembl:ENSG00000137880|Vega:OTTHUMG00000130069 +2645 GCK MIM:138079|HGNC:HGNC:4195|Ensembl:ENSG00000106633|Vega:OTTHUMG00000022903 +2646 GCKR MIM:600842|HGNC:HGNC:4196|Ensembl:ENSG00000084734|Vega:OTTHUMG00000128426 +2647 BLOC1S1 MIM:601444|HGNC:HGNC:4200|Ensembl:ENSG00000135441|Vega:OTTHUMG00000169962 +2648 KAT2A MIM:602301|HGNC:HGNC:4201|Ensembl:ENSG00000108773|Vega:OTTHUMG00000133504 +2649 NR6A1 MIM:602778|HGNC:HGNC:7985|Ensembl:ENSG00000148200|Vega:OTTHUMG00000020661 +2650 GCNT1 MIM:600391|HGNC:HGNC:4203|Ensembl:ENSG00000187210|Vega:OTTHUMG00000020044 +2651 GCNT2 MIM:600429|HGNC:HGNC:4204|Ensembl:ENSG00000111846|Vega:OTTHUMG00000014244 +2652 OPN1MW MIM:300821|HGNC:HGNC:4206|Ensembl:ENSG00000268221|Vega:OTTHUMG00000022652 +2653 GCSH MIM:238330|HGNC:HGNC:4208|Ensembl:ENSG00000140905|Vega:OTTHUMG00000137626 +2656 GCY MIM:475000|HGNC:HGNC:4211 +2657 GDF1 MIM:602880|HGNC:HGNC:4214|Ensembl:ENSG00000130283|Ensembl:ENSG00000223802|Vega:OTTHUMG00000183278 +2658 GDF2 MIM:605120|HGNC:HGNC:4217|Ensembl:ENSG00000263761|Vega:OTTHUMG00000188320 +2660 MSTN MIM:601788|HGNC:HGNC:4223|Ensembl:ENSG00000138379|Vega:OTTHUMG00000132663 +2661 GDF9 MIM:601918|HGNC:HGNC:4224|Ensembl:ENSG00000164404|Vega:OTTHUMG00000059842 +2662 GDF10 MIM:601361|HGNC:HGNC:4215|Ensembl:ENSG00000266524|Vega:OTTHUMG00000188319 +2664 GDI1 MIM:300104|HGNC:HGNC:4226|Ensembl:ENSG00000203879|Vega:OTTHUMG00000033293 +2665 GDI2 MIM:600767|HGNC:HGNC:4227|Ensembl:ENSG00000057608|Vega:OTTHUMG00000017607 +2667 GDI2P1 HGNC:HGNC:4228 +2668 GDNF MIM:600837|HGNC:HGNC:4232|Ensembl:ENSG00000168621|Vega:OTTHUMG00000090809 +2669 GEM MIM:600164|HGNC:HGNC:4234|Ensembl:ENSG00000164949|Vega:OTTHUMG00000164392 +2670 GFAP MIM:137780|HGNC:HGNC:4235|Ensembl:ENSG00000131095|Vega:OTTHUMG00000179866 +2671 GFER MIM:600924|HGNC:HGNC:4236|Ensembl:ENSG00000127554|Vega:OTTHUMG00000176896 +2672 GFI1 MIM:600871|HGNC:HGNC:4237|Ensembl:ENSG00000162676|Vega:OTTHUMG00000010897 +2673 GFPT1 MIM:138292|HGNC:HGNC:4241|Ensembl:ENSG00000198380|Vega:OTTHUMG00000152666 +2674 GFRA1 MIM:601496|HGNC:HGNC:4243|Ensembl:ENSG00000151892|Vega:OTTHUMG00000019097 +2675 GFRA2 MIM:601956|HGNC:HGNC:4244|Ensembl:ENSG00000168546|Vega:OTTHUMG00000163897 +2676 GFRA3 MIM:605710|HGNC:HGNC:4245|Ensembl:ENSG00000146013|Vega:OTTHUMG00000129200 +2677 GGCX MIM:137167|HGNC:HGNC:4247|Ensembl:ENSG00000115486|Vega:OTTHUMG00000130173 +2678 GGT1 MIM:612346|HGNC:HGNC:4250|Ensembl:ENSG00000100031|Vega:OTTHUMG00000030859 +2679 GGT3P HGNC:HGNC:4252|Ensembl:ENSG00000197421 +2681 GGTA1P MIM:104175|HGNC:HGNC:4253|Ensembl:ENSG00000204136 +2683 B4GALT1 MIM:137060|HGNC:HGNC:924|Ensembl:ENSG00000086062|Vega:OTTHUMG00000019764 +2686 GGT7 MIM:612342|HGNC:HGNC:4259|Ensembl:ENSG00000131067|Vega:OTTHUMG00000032314 +2687 GGT5 MIM:137168|HGNC:HGNC:4260|Ensembl:ENSG00000099998|Vega:OTTHUMG00000150796 +2688 GH1 MIM:139250|HGNC:HGNC:4261|Ensembl:ENSG00000259384|Vega:OTTHUMG00000172293 +2689 GH2 MIM:139240|HGNC:HGNC:4262|Ensembl:ENSG00000136487|Vega:OTTHUMG00000172284 +2690 GHR MIM:600946|HGNC:HGNC:4263|Ensembl:ENSG00000112964|Vega:OTTHUMG00000094791 +2691 GHRH MIM:139190|HGNC:HGNC:4265|Ensembl:ENSG00000118702|Vega:OTTHUMG00000032413 +2692 GHRHR MIM:139191|HGNC:HGNC:4266|Ensembl:ENSG00000106128|Vega:OTTHUMG00000152801 +2693 GHSR MIM:601898|HGNC:HGNC:4267|Ensembl:ENSG00000121853|Vega:OTTHUMG00000156946 +2694 GIF MIM:609342|HGNC:HGNC:4268|Ensembl:ENSG00000134812|Vega:OTTHUMG00000167399 +2695 GIP MIM:137240|HGNC:HGNC:4270|Ensembl:ENSG00000159224|Vega:OTTHUMG00000161171 +2696 GIPR MIM:137241|HGNC:HGNC:4271|Ensembl:ENSG00000010310|Vega:OTTHUMG00000182129 +2697 GJA1 MIM:121014|HGNC:HGNC:4274|Ensembl:ENSG00000152661|Vega:OTTHUMG00000015479 +2698 GJA1P1 HGNC:HGNC:4275 +2700 GJA3 MIM:121015|HGNC:HGNC:4277|Ensembl:ENSG00000121743|Vega:OTTHUMG00000016510 +2701 GJA4 MIM:121012|HGNC:HGNC:4278|Ensembl:ENSG00000187513|Vega:OTTHUMG00000004050 +2702 GJA5 MIM:121013|HGNC:HGNC:4279|Ensembl:ENSG00000265107|Vega:OTTHUMG00000014020 +2703 GJA8 MIM:600897|HGNC:HGNC:4281|Ensembl:ENSG00000121634|Vega:OTTHUMG00000024085 +2705 GJB1 MIM:304040|HGNC:HGNC:4283|Ensembl:ENSG00000169562|Vega:OTTHUMG00000021797 +2706 GJB2 MIM:121011|HGNC:HGNC:4284|Ensembl:ENSG00000165474|Vega:OTTHUMG00000016513 +2707 GJB3 MIM:603324|HGNC:HGNC:4285|Ensembl:ENSG00000188910|Vega:OTTHUMG00000004051 +2709 GJB5 MIM:604493|HGNC:HGNC:4287|Ensembl:ENSG00000189280|Vega:OTTHUMG00000004053 +2710 GK MIM:300474|HGNC:HGNC:4289|Ensembl:ENSG00000198814|Vega:OTTHUMG00000021328 +2712 GK2 MIM:600148|HGNC:HGNC:4291|Ensembl:ENSG00000196475|Vega:OTTHUMG00000130199 +2713 GK3P MIM:600149|HGNC:HGNC:4292|Ensembl:ENSG00000229894|Vega:OTTHUMG00000161293 +2716 GK4P HGNC:HGNC:4295 +2717 GLA MIM:300644|HGNC:HGNC:4296|Ensembl:ENSG00000102393|Vega:OTTHUMG00000022026 +2719 GPC3 MIM:300037|HGNC:HGNC:4451|Ensembl:ENSG00000147257|Vega:OTTHUMG00000022448 +2720 GLB1 MIM:611458|HGNC:HGNC:4298|Ensembl:ENSG00000170266|Vega:OTTHUMG00000155781 +2722 GLC1B MIM:606689|HGNC:HGNC:4302 +2723 GLC1C MIM:601682|HGNC:HGNC:4303 +2724 GLC1D MIM:602429|HGNC:HGNC:4304 +2727 GLC2A HGNC:HGNC:4307 +2728 GLC3B MIM:600975|HGNC:HGNC:4309 +2729 GCLC MIM:606857|HGNC:HGNC:4311|Ensembl:ENSG00000001084|Vega:OTTHUMG00000160220 +2730 GCLM MIM:601176|HGNC:HGNC:4312|Ensembl:ENSG00000023909|Vega:OTTHUMG00000010562 +2731 GLDC MIM:238300|HGNC:HGNC:4313|Ensembl:ENSG00000178445|Vega:OTTHUMG00000019524 +2732 GLDCP1 HGNC:HGNC:4314 +2733 GLE1 MIM:603371|HGNC:HGNC:4315|Ensembl:ENSG00000119392|Vega:OTTHUMG00000020749 +2734 GLG1 MIM:600753|HGNC:HGNC:4316|Ensembl:ENSG00000090863|Vega:OTTHUMG00000177174 +2735 GLI1 MIM:165220|HGNC:HGNC:4317|Ensembl:ENSG00000111087|Vega:OTTHUMG00000167332 +2736 GLI2 MIM:165230|HGNC:HGNC:4318|Ensembl:ENSG00000074047|Vega:OTTHUMG00000153741 +2737 GLI3 MIM:165240|HGNC:HGNC:4319|Ensembl:ENSG00000106571|Vega:OTTHUMG00000023630 +2738 GLI4 MIM:165280|HGNC:HGNC:4320|Ensembl:ENSG00000250571|Vega:OTTHUMG00000164952 +2739 GLO1 MIM:138750|HGNC:HGNC:4323|Ensembl:ENSG00000124767|Vega:OTTHUMG00000014636 +2740 GLP1R MIM:138032|HGNC:HGNC:4324|Ensembl:ENSG00000112164|Vega:OTTHUMG00000014638 +2741 GLRA1 MIM:138491|HGNC:HGNC:4326|Ensembl:ENSG00000145888|Vega:OTTHUMG00000130121 +2742 GLRA2 MIM:305990|HGNC:HGNC:4327|Ensembl:ENSG00000101958|Vega:OTTHUMG00000021166 +2743 GLRB MIM:138492|HGNC:HGNC:4329|Ensembl:ENSG00000109738|Vega:OTTHUMG00000161954 +2744 GLS MIM:138280|HGNC:HGNC:4331|Ensembl:ENSG00000115419|Vega:OTTHUMG00000132701 +2745 GLRX MIM:600443|HGNC:HGNC:4330|Ensembl:ENSG00000173221|Vega:OTTHUMG00000121167 +2746 GLUD1 MIM:138130|HGNC:HGNC:4335|Ensembl:ENSG00000148672|Vega:OTTHUMG00000018666 +2747 GLUD2 MIM:300144|HGNC:HGNC:4336|Ensembl:ENSG00000182890|Vega:OTTHUMG00000022320 +2749 GLUD1P3 HGNC:HGNC:4338|Ensembl:ENSG00000250959 +2750 GLUD1P4 HGNC:HGNC:4339 +2751 GLUD1P5 HGNC:HGNC:4340 +2752 GLUL MIM:138290|HGNC:HGNC:4341|Ensembl:ENSG00000135821|Vega:OTTHUMG00000037407 +2753 GLULP1 HGNC:HGNC:4342 +2754 GLULP2 HGNC:HGNC:4343 +2757 GLYB MIM:138480|HGNC:HGNC:4363 +2759 GLYS1 MIM:233100|HGNC:HGNC:4365 +2760 GM2A MIM:613109|HGNC:HGNC:4367|Ensembl:ENSG00000196743|Vega:OTTHUMG00000130124 +2761 GM2AP1 HGNC:HGNC:4368 +2762 GMDS MIM:602884|HGNC:HGNC:4369|Ensembl:ENSG00000112699|Vega:OTTHUMG00000016143 +2763 GMFA HGNC:HGNC:4372 +2764 GMFB MIM:601713|HGNC:HGNC:4373|Ensembl:ENSG00000197045|Vega:OTTHUMG00000140307 +2765 GML MIM:602370|HGNC:HGNC:4375|Ensembl:ENSG00000104499|Vega:OTTHUMG00000164656 +2766 GMPR MIM:139265|HGNC:HGNC:4376|Ensembl:ENSG00000137198|Vega:OTTHUMG00000014302 +2767 GNA11 MIM:139313|HGNC:HGNC:4379|Ensembl:ENSG00000088256|Vega:OTTHUMG00000180631 +2768 GNA12 MIM:604394|HGNC:HGNC:4380|Ensembl:ENSG00000146535|Vega:OTTHUMG00000023064 +2769 GNA15 MIM:139314|HGNC:HGNC:4383|Ensembl:ENSG00000060558|Vega:OTTHUMG00000180637 +2770 GNAI1 MIM:139310|HGNC:HGNC:4384|Ensembl:ENSG00000127955|Vega:OTTHUMG00000023523 +2771 GNAI2 MIM:139360|HGNC:HGNC:4385|Ensembl:ENSG00000114353|Vega:OTTHUMG00000156940 +2772 GNAI2P1 MIM:139180|HGNC:HGNC:4386 +2773 GNAI3 MIM:139370|HGNC:HGNC:4387|Ensembl:ENSG00000065135|Vega:OTTHUMG00000189112 +2774 GNAL MIM:139312|HGNC:HGNC:4388|Ensembl:ENSG00000141404|Vega:OTTHUMG00000131660 +2775 GNAO1 MIM:139311|HGNC:HGNC:4389|Ensembl:ENSG00000087258|Vega:OTTHUMG00000133241 +2776 GNAQ MIM:600998|HGNC:HGNC:4390|Ensembl:ENSG00000156052|Vega:OTTHUMG00000020059 +2777 GNAQP1 HGNC:HGNC:4391 +2778 GNAS MIM:139320|HGNC:HGNC:4392|Ensembl:ENSG00000087460|Vega:OTTHUMG00000033069 +2779 GNAT1 MIM:139330|HGNC:HGNC:4393|Ensembl:ENSG00000114349|Vega:OTTHUMG00000156808 +2780 GNAT2 MIM:139340|HGNC:HGNC:4394|Ensembl:ENSG00000134183|Vega:OTTHUMG00000011639 +2781 GNAZ MIM:139160|HGNC:HGNC:4395|Ensembl:ENSG00000128266|Vega:OTTHUMG00000150611 +2782 GNB1 MIM:139380|HGNC:HGNC:4396|Ensembl:ENSG00000078369|Vega:OTTHUMG00000000940 +2783 GNB2 MIM:139390|HGNC:HGNC:4398|Ensembl:ENSG00000172354|Vega:OTTHUMG00000137419 +2784 GNB3 MIM:139130|HGNC:HGNC:4400|Ensembl:ENSG00000111664|Vega:OTTHUMG00000168517 +2785 GNG3 MIM:608941|HGNC:HGNC:4405|Ensembl:ENSG00000162188|Vega:OTTHUMG00000167560 +2786 GNG4 MIM:604388|HGNC:HGNC:4407|Ensembl:ENSG00000168243|Vega:OTTHUMG00000040740 +2787 GNG5 MIM:600874|HGNC:HGNC:4408|Ensembl:ENSG00000174021|Vega:OTTHUMG00000009858 +2788 GNG7 MIM:604430|HGNC:HGNC:4410|Ensembl:ENSG00000176533|Vega:OTTHUMG00000180435 +2789 GNG5P1 HGNC:HGNC:4409 +2790 GNG10 MIM:604389|HGNC:HGNC:4402|Ensembl:ENSG00000242616|Vega:OTTHUMG00000157193 +2791 GNG11 MIM:604390|HGNC:HGNC:4403|Ensembl:ENSG00000127920|Vega:OTTHUMG00000023411 +2792 GNGT1 MIM:189970|HGNC:HGNC:4411|Ensembl:ENSG00000127928|Vega:OTTHUMG00000022908 +2793 GNGT2 MIM:139391|HGNC:HGNC:4412|Ensembl:ENSG00000167083|Vega:OTTHUMG00000161308 +2794 GNL1 MIM:143024|HGNC:HGNC:4413|Ensembl:ENSG00000204590|Vega:OTTHUMG00000031137 +2796 GNRH1 MIM:152760|HGNC:HGNC:4419|Ensembl:ENSG00000147437|Vega:OTTHUMG00000163852 +2797 GNRH2 MIM:602352|HGNC:HGNC:4420|Ensembl:ENSG00000125787|Vega:OTTHUMG00000031723 +2798 GNRHR MIM:138850|HGNC:HGNC:4421|Ensembl:ENSG00000109163|Vega:OTTHUMG00000129302 +2799 GNS MIM:607664|HGNC:HGNC:4422|Ensembl:ENSG00000135677|Vega:OTTHUMG00000168819 +2800 GOLGA1 MIM:602502|HGNC:HGNC:4424|Ensembl:ENSG00000136935|Vega:OTTHUMG00000020665 +2801 GOLGA2 MIM:602580|HGNC:HGNC:4425|Ensembl:ENSG00000167110|Vega:OTTHUMG00000020732 +2802 GOLGA3 MIM:602581|HGNC:HGNC:4426|Ensembl:ENSG00000090615|Vega:OTTHUMG00000168023 +2803 GOLGA4 MIM:602509|HGNC:HGNC:4427|Ensembl:ENSG00000144674|Vega:OTTHUMG00000130799 +2804 GOLGB1 MIM:602500|HGNC:HGNC:4429|Ensembl:ENSG00000173230|Vega:OTTHUMG00000159411 +2805 GOT1 MIM:138180|HGNC:HGNC:4432|Ensembl:ENSG00000120053|Vega:OTTHUMG00000018882 +2806 GOT2 MIM:138150|HGNC:HGNC:4433|Ensembl:ENSG00000125166|Vega:OTTHUMG00000133769 +2810 SFN MIM:601290|HGNC:HGNC:10773|Ensembl:ENSG00000175793|Vega:OTTHUMG00000004093 +2811 GP1BA MIM:606672|HGNC:HGNC:4439|Ensembl:ENSG00000185245|Vega:OTTHUMG00000177946 +2812 GP1BB MIM:138720|HGNC:HGNC:4440|Ensembl:ENSG00000203618|Vega:OTTHUMG00000150397 +2813 GP2 MIM:602977|HGNC:HGNC:4441|Ensembl:ENSG00000169347|Vega:OTTHUMG00000131489 +2814 GP5 MIM:173511|HGNC:HGNC:4443|Ensembl:ENSG00000178732|Vega:OTTHUMG00000150345 +2815 GP9 MIM:173515|HGNC:HGNC:4444|Ensembl:ENSG00000169704|Vega:OTTHUMG00000159944 +2817 GPC1 MIM:600395|HGNC:HGNC:4449|Ensembl:ENSG00000063660|Vega:OTTHUMG00000133349 +2819 GPD1 MIM:138420|HGNC:HGNC:4455|Ensembl:ENSG00000167588|Vega:OTTHUMG00000169813 +2820 GPD2 MIM:138430|HGNC:HGNC:4456|Ensembl:ENSG00000115159|Vega:OTTHUMG00000131951 +2821 GPI MIM:172400|HGNC:HGNC:4458|Ensembl:ENSG00000105220|Vega:OTTHUMG00000182087 +2822 GPLD1 MIM:602515|HGNC:HGNC:4459|Ensembl:ENSG00000112293|Vega:OTTHUMG00000016104 +2823 GPM6A MIM:601275|HGNC:HGNC:4460|Ensembl:ENSG00000150625|Vega:OTTHUMG00000160760 +2824 GPM6B MIM:300051|HGNC:HGNC:4461|Ensembl:ENSG00000046653|Vega:OTTHUMG00000021162 +2825 GPR1 MIM:600239|HGNC:HGNC:4463|Ensembl:ENSG00000183671|Vega:OTTHUMG00000132894 +2826 CCR10 MIM:600240|HGNC:HGNC:4474|Ensembl:ENSG00000184451|Vega:OTTHUMG00000132301 +2827 GPR3 MIM:600241|HGNC:HGNC:4484|Ensembl:ENSG00000181773|Vega:OTTHUMG00000003397 +2828 GPR4 MIM:600551|HGNC:HGNC:4497|Ensembl:ENSG00000177464|Vega:OTTHUMG00000182126 +2829 XCR1 MIM:600552|HGNC:HGNC:1625|Ensembl:ENSG00000173578|Vega:OTTHUMG00000133449 +2830 GPR6 MIM:600553|HGNC:HGNC:4515|Ensembl:ENSG00000146360|Vega:OTTHUMG00000015354 +2831 NPBWR1 MIM:600730|HGNC:HGNC:4522|Ensembl:ENSG00000183729|Vega:OTTHUMG00000164275 +2832 NPBWR2 MIM:600731|HGNC:HGNC:4530|Ensembl:ENSG00000125522|Vega:OTTHUMG00000033032 +2833 CXCR3 MIM:300574|HGNC:HGNC:4540|Ensembl:ENSG00000186810|Vega:OTTHUMG00000033326 +2834 PRLHR MIM:600895|HGNC:HGNC:4464|Ensembl:ENSG00000119973|Vega:OTTHUMG00000019136 +2835 GPR12 MIM:600752|HGNC:HGNC:4466|Ensembl:ENSG00000132975|Vega:OTTHUMG00000016620 +2837 UTS2R MIM:600896|HGNC:HGNC:4468|Ensembl:ENSG00000181408|Vega:OTTHUMG00000178835 +2838 GPR15 MIM:601166|HGNC:HGNC:4469|Ensembl:ENSG00000154165|Vega:OTTHUMG00000160017 +2840 GPR17 MIM:603071|HGNC:HGNC:4471|Ensembl:ENSG00000144230|Vega:OTTHUMG00000131533 +2841 GPR18 MIM:602042|HGNC:HGNC:4472|Ensembl:ENSG00000125245|Vega:OTTHUMG00000017266 +2842 GPR19 MIM:602927|HGNC:HGNC:4473|Ensembl:ENSG00000183150|Vega:OTTHUMG00000168705 +2843 GPR20 MIM:601908|HGNC:HGNC:4475|Ensembl:ENSG00000204882|Vega:OTTHUMG00000164484 +2844 GPR21 MIM:601909|HGNC:HGNC:4476|Ensembl:ENSG00000011454|Ensembl:ENSG00000188394|Vega:OTTHUMG00000020631 +2845 GPR22 MIM:601910|HGNC:HGNC:4477|Ensembl:ENSG00000172209|Vega:OTTHUMG00000154902 +2846 LPAR4 MIM:300086|HGNC:HGNC:4478|Ensembl:ENSG00000147145|Vega:OTTHUMG00000021895 +2847 MCHR1 MIM:601751|HGNC:HGNC:4479|Ensembl:ENSG00000128285|Vega:OTTHUMG00000150256 +2848 GPR25 MIM:602174|HGNC:HGNC:4480|Ensembl:ENSG00000170128|Vega:OTTHUMG00000035788 +2849 GPR26 MIM:604847|HGNC:HGNC:4481|Ensembl:ENSG00000154478|Vega:OTTHUMG00000019204 +2850 GPR27 MIM:605187|HGNC:HGNC:4482|Ensembl:ENSG00000170837|Vega:OTTHUMG00000158810 +2852 GPER1 MIM:601805|HGNC:HGNC:4485|Ensembl:ENSG00000164850|Vega:OTTHUMG00000023680 +2853 GPR31 MIM:602043|HGNC:HGNC:4486|Ensembl:ENSG00000120436|Vega:OTTHUMG00000016013 +2854 GPR32 MIM:603195|HGNC:HGNC:4487|Ensembl:ENSG00000142511|Vega:OTTHUMG00000183079 +2855 GPR32P1 HGNC:HGNC:4488 +2856 GPR33 MIM:610118|HGNC:HGNC:4489|Ensembl:ENSG00000214943|Vega:OTTHUMG00000154921 +2857 GPR34 MIM:300241|HGNC:HGNC:4490|Ensembl:ENSG00000171659|Vega:OTTHUMG00000021375 +2859 GPR35 MIM:602646|HGNC:HGNC:4492|Ensembl:ENSG00000178623|Vega:OTTHUMG00000133356 +2860 GPR36 HGNC:HGNC:4493 +2861 GPR37 MIM:602583|HGNC:HGNC:4494|Ensembl:ENSG00000170775|Vega:OTTHUMG00000157197 +2862 MLNR MIM:602885|HGNC:HGNC:4495|Ensembl:ENSG00000102539|Vega:OTTHUMG00000016909 +2863 GPR39 MIM:602886|HGNC:HGNC:4496|Ensembl:ENSG00000183840|Vega:OTTHUMG00000131679 +2864 FFAR1 MIM:603820|HGNC:HGNC:4498|Ensembl:ENSG00000126266|Vega:OTTHUMG00000188261 +2865 FFAR3 MIM:603821|HGNC:HGNC:4499|Ensembl:ENSG00000185897|Vega:OTTHUMG00000172514 +2866 GPR42 MIM:603822|HGNC:HGNC:4500 +2867 FFAR2 MIM:603823|HGNC:HGNC:4501|Ensembl:ENSG00000126262|Vega:OTTHUMG00000183303 +2868 GRK4 MIM:137026|HGNC:HGNC:4543|Ensembl:ENSG00000125388|Vega:OTTHUMG00000159914 +2869 GRK5 MIM:600870|HGNC:HGNC:4544|Ensembl:ENSG00000198873|Vega:OTTHUMG00000019149 +2870 GRK6 MIM:600869|HGNC:HGNC:4545|Ensembl:ENSG00000198055|Vega:OTTHUMG00000163401 +2871 GRK6P1 HGNC:HGNC:4547 +2872 MKNK2 MIM:605069|HGNC:HGNC:7111|Ensembl:ENSG00000099875|Vega:OTTHUMG00000180020 +2873 GPS1 MIM:601934|HGNC:HGNC:4549|Ensembl:ENSG00000169727|Vega:OTTHUMG00000178484 +2874 GPS2 MIM:601935|HGNC:HGNC:4550|Ensembl:ENSG00000132522|Vega:OTTHUMG00000102198 +2875 GPT MIM:138200|HGNC:HGNC:4552|Ensembl:ENSG00000167701|Vega:OTTHUMG00000165176 +2876 GPX1 MIM:138320|HGNC:HGNC:4553|Ensembl:ENSG00000233276|Vega:OTTHUMG00000156837 +2877 GPX2 MIM:138319|HGNC:HGNC:4554|Ensembl:ENSG00000176153|Vega:OTTHUMG00000171677 +2878 GPX3 MIM:138321|HGNC:HGNC:4555|Ensembl:ENSG00000211445|Vega:OTTHUMG00000163693 +2879 GPX4 MIM:138322|HGNC:HGNC:4556|Ensembl:ENSG00000167468|Vega:OTTHUMG00000181874 +2880 GPX5 MIM:603435|HGNC:HGNC:4557|Ensembl:ENSG00000224586|Vega:OTTHUMG00000016307 +2882 GPX7 MIM:615784|HGNC:HGNC:4559|Ensembl:ENSG00000116157|Vega:OTTHUMG00000008322 +2884 GPX1P2 HGNC:HGNC:4561 +2885 GRB2 MIM:108355|HGNC:HGNC:4566|Ensembl:ENSG00000177885|Vega:OTTHUMG00000134332 +2886 GRB7 MIM:601522|HGNC:HGNC:4567|Ensembl:ENSG00000141738|Vega:OTTHUMG00000133253 +2887 GRB10 MIM:601523|HGNC:HGNC:4564|Ensembl:ENSG00000106070|Vega:OTTHUMG00000150622 +2888 GRB14 MIM:601524|HGNC:HGNC:4565|Ensembl:ENSG00000115290|Vega:OTTHUMG00000132135 +2889 RAPGEF1 MIM:600303|HGNC:HGNC:4568|Ensembl:ENSG00000107263|Vega:OTTHUMG00000020829 +2890 GRIA1 MIM:138248|HGNC:HGNC:4571|Ensembl:ENSG00000155511|Vega:OTTHUMG00000130148 +2891 GRIA2 MIM:138247|HGNC:HGNC:4572|Ensembl:ENSG00000120251|Vega:OTTHUMG00000133836 +2892 GRIA3 MIM:305915|HGNC:HGNC:4573|Ensembl:ENSG00000125675|Vega:OTTHUMG00000022685 +2893 GRIA4 MIM:138246|HGNC:HGNC:4574|Ensembl:ENSG00000152578|Vega:OTTHUMG00000166236 +2894 GRID1 MIM:610659|HGNC:HGNC:4575|Ensembl:ENSG00000182771|Vega:OTTHUMG00000018650 +2895 GRID2 MIM:602368|HGNC:HGNC:4576|Ensembl:ENSG00000152208|Vega:OTTHUMG00000130975 +2896 GRN MIM:138945|HGNC:HGNC:4601|Ensembl:ENSG00000030582|Vega:OTTHUMG00000181816 +2897 GRIK1 MIM:138245|HGNC:HGNC:4579|Ensembl:ENSG00000171189|Vega:OTTHUMG00000078879 +2898 GRIK2 MIM:138244|HGNC:HGNC:4580|Ensembl:ENSG00000164418|Vega:OTTHUMG00000016328 +2899 GRIK3 MIM:138243|HGNC:HGNC:4581|Ensembl:ENSG00000163873|Vega:OTTHUMG00000004189 +2900 GRIK4 MIM:600282|HGNC:HGNC:4582|Ensembl:ENSG00000149403|Vega:OTTHUMG00000048255 +2901 GRIK5 MIM:600283|HGNC:HGNC:4583|Ensembl:ENSG00000105737|Vega:OTTHUMG00000044573 +2902 GRIN1 MIM:138249|HGNC:HGNC:4584|Ensembl:ENSG00000176884|Vega:OTTHUMG00000020976 +2903 GRIN2A MIM:138253|HGNC:HGNC:4585|Ensembl:ENSG00000183454|Vega:OTTHUMG00000129721 +2904 GRIN2B MIM:138252|HGNC:HGNC:4586|Ensembl:ENSG00000273079|Vega:OTTHUMG00000137373 +2905 GRIN2C MIM:138254|HGNC:HGNC:4587|Ensembl:ENSG00000161509|Vega:OTTHUMG00000044524 +2906 GRIN2D MIM:602717|HGNC:HGNC:4588|Ensembl:ENSG00000105464|Vega:OTTHUMG00000183304 +2907 GRINA MIM:138251|HGNC:HGNC:4589|Ensembl:ENSG00000178719|Vega:OTTHUMG00000165433 +2908 NR3C1 MIM:138040|HGNC:HGNC:7978|Ensembl:ENSG00000113580|Vega:OTTHUMG00000129677 +2909 ARHGAP35 MIM:605277|HGNC:HGNC:4591|Ensembl:ENSG00000160007|Vega:OTTHUMG00000183438 +2910 NR3C1P1 MIM:138060|HGNC:HGNC:4592 +2911 GRM1 MIM:604473|HGNC:HGNC:4593|Ensembl:ENSG00000152822|Vega:OTTHUMG00000015752 +2912 GRM2 MIM:604099|HGNC:HGNC:4594|Ensembl:ENSG00000164082|Vega:OTTHUMG00000156902 +2913 GRM3 MIM:601115|HGNC:HGNC:4595|Ensembl:ENSG00000198822|Vega:OTTHUMG00000022884 +2914 GRM4 MIM:604100|HGNC:HGNC:4596|Ensembl:ENSG00000124493|Vega:OTTHUMG00000014538 +2915 GRM5 MIM:604102|HGNC:HGNC:4597|Ensembl:ENSG00000168959|Vega:OTTHUMG00000134306 +2916 GRM6 MIM:604096|HGNC:HGNC:4598|Ensembl:ENSG00000113262|Vega:OTTHUMG00000130889 +2917 GRM7 MIM:604101|HGNC:HGNC:4599|Ensembl:ENSG00000196277|Vega:OTTHUMG00000125549 +2918 GRM8 MIM:601116|HGNC:HGNC:4600|Ensembl:ENSG00000179603|Vega:OTTHUMG00000022888 +2919 CXCL1 MIM:155730|HGNC:HGNC:4602|Ensembl:ENSG00000163739|Vega:OTTHUMG00000160866 +2920 CXCL2 MIM:139110|HGNC:HGNC:4603|Ensembl:ENSG00000081041|Vega:OTTHUMG00000160865 +2921 CXCL3 MIM:139111|HGNC:HGNC:4604|Ensembl:ENSG00000163734|Vega:OTTHUMG00000160861 +2922 GRP MIM:137260|HGNC:HGNC:4605|Ensembl:ENSG00000134443|Vega:OTTHUMG00000132760 +2923 PDIA3 MIM:602046|HGNC:HGNC:4606|Ensembl:ENSG00000167004|Vega:OTTHUMG00000044444 +2925 GRPR MIM:305670|HGNC:HGNC:4609|Ensembl:ENSG00000126010|Vega:OTTHUMG00000021189 +2926 GRSF1 MIM:604851|HGNC:HGNC:4610|Ensembl:ENSG00000132463|Vega:OTTHUMG00000160846 +2928 GSC2 MIM:601845|HGNC:HGNC:4613|Ensembl:ENSG00000063515|Vega:OTTHUMG00000150122 +2931 GSK3A MIM:606784|HGNC:HGNC:4616|Ensembl:ENSG00000105723|Vega:OTTHUMG00000150722 +2932 GSK3B MIM:605004|HGNC:HGNC:4617|Ensembl:ENSG00000082701|Vega:OTTHUMG00000133765 +2933 GSM1 MIM:190100|HGNC:HGNC:4619 +2934 GSN MIM:137350|HGNC:HGNC:4620|Ensembl:ENSG00000148180|Vega:OTTHUMG00000020584 +2935 GSPT1 MIM:139259|HGNC:HGNC:4621|Ensembl:ENSG00000103342|Vega:OTTHUMG00000172956 +2936 GSR MIM:138300|HGNC:HGNC:4623|Ensembl:ENSG00000104687|Vega:OTTHUMG00000163946 +2937 GSS MIM:601002|HGNC:HGNC:4624|Ensembl:ENSG00000100983|Vega:OTTHUMG00000032315 +2938 GSTA1 MIM:138359|HGNC:HGNC:4626|Ensembl:ENSG00000243955|Vega:OTTHUMG00000014861 +2939 GSTA2 MIM:138360|HGNC:HGNC:4627|Ensembl:ENSG00000244067|Vega:OTTHUMG00000016263 +2940 GSTA3 MIM:605449|HGNC:HGNC:4628|Ensembl:ENSG00000174156|Vega:OTTHUMG00000014865 +2941 GSTA4 MIM:605450|HGNC:HGNC:4629|Ensembl:ENSG00000170899|Vega:OTTHUMG00000014868 +2942 GSTA6P HGNC:HGNC:4630 +2944 GSTM1 MIM:138350|HGNC:HGNC:4632|Ensembl:ENSG00000134184|Vega:OTTHUMG00000011635 +2946 GSTM2 MIM:138380|HGNC:HGNC:4634|Ensembl:ENSG00000213366|Vega:OTTHUMG00000011638 +2947 GSTM3 MIM:138390|HGNC:HGNC:4635|Ensembl:ENSG00000134202|Vega:OTTHUMG00000011640 +2948 GSTM4 MIM:138333|HGNC:HGNC:4636|Ensembl:ENSG00000168765|Vega:OTTHUMG00000011642 +2949 GSTM5 MIM:138385|HGNC:HGNC:4637|Ensembl:ENSG00000134201|Vega:OTTHUMG00000011644 +2950 GSTP1 MIM:134660|HGNC:HGNC:4638|Ensembl:ENSG00000084207|Vega:OTTHUMG00000137430 +2951 GSTP1P1 HGNC:HGNC:4640 +2952 GSTT1 MIM:600436|HGNC:HGNC:4641 +2953 GSTT2 MIM:600437|HGNC:HGNC:4642|Ensembl:ENSG00000099984|Vega:OTTHUMG00000150786 +2954 GSTZ1 MIM:603758|HGNC:HGNC:4643|Ensembl:ENSG00000100577|Vega:OTTHUMG00000171551 +2956 MSH6 MIM:600678|HGNC:HGNC:7329|Ensembl:ENSG00000116062|Vega:OTTHUMG00000129129 +2957 GTF2A1 MIM:600520|HGNC:HGNC:4646|Ensembl:ENSG00000165417|Vega:OTTHUMG00000171414 +2958 GTF2A2 MIM:600519|HGNC:HGNC:4647|Ensembl:ENSG00000140307|Vega:OTTHUMG00000132725 +2959 GTF2B MIM:189963|HGNC:HGNC:4648|Ensembl:ENSG00000137947|Vega:OTTHUMG00000010611 +2960 GTF2E1 MIM:189962|HGNC:HGNC:4650|Ensembl:ENSG00000153767|Vega:OTTHUMG00000159667 +2961 GTF2E2 MIM:189964|HGNC:HGNC:4651|Ensembl:ENSG00000197265|Vega:OTTHUMG00000163934 +2962 GTF2F1 MIM:189968|HGNC:HGNC:4652|Ensembl:ENSG00000125651|Vega:OTTHUMG00000168087 +2963 GTF2F2 MIM:189969|HGNC:HGNC:4653|Ensembl:ENSG00000188342|Vega:OTTHUMG00000016849 +2964 GTF2F2P1 HGNC:HGNC:4654 +2965 GTF2H1 MIM:189972|HGNC:HGNC:4655|Ensembl:ENSG00000110768|Vega:OTTHUMG00000167690 +2966 GTF2H2 MIM:601748|HGNC:HGNC:4656|Ensembl:ENSG00000145736|Vega:OTTHUMG00000164542 +2967 GTF2H3 MIM:601750|HGNC:HGNC:4657|Ensembl:ENSG00000111358|Vega:OTTHUMG00000168697 +2968 GTF2H4 MIM:601760|HGNC:HGNC:4658|Ensembl:ENSG00000213780|Vega:OTTHUMG00000031043 +2969 GTF2I MIM:601679|HGNC:HGNC:4659|Ensembl:ENSG00000263001|Vega:OTTHUMG00000156237 +2970 GTF2IP1 HGNC:HGNC:4660|Ensembl:ENSG00000277053 +2971 GTF3A MIM:600860|HGNC:HGNC:4662|Ensembl:ENSG00000122034|Vega:OTTHUMG00000016632 +2972 BRF1 MIM:604902|HGNC:HGNC:11551|Ensembl:ENSG00000185024|Vega:OTTHUMG00000029884 +2973 GTS MIM:137580|HGNC:HGNC:4671 +2974 GUCY1B2 MIM:603695|HGNC:HGNC:4686|Ensembl:ENSG00000123201 +2975 GTF3C1 MIM:603246|HGNC:HGNC:4664|Ensembl:ENSG00000077235|Vega:OTTHUMG00000176805 +2976 GTF3C2 MIM:604883|HGNC:HGNC:4665|Ensembl:ENSG00000115207|Vega:OTTHUMG00000097785 +2977 GUCY1A2 MIM:601244|HGNC:HGNC:4684|Ensembl:ENSG00000152402|Vega:OTTHUMG00000166296 +2978 GUCA1A MIM:600364|HGNC:HGNC:4678|Ensembl:ENSG00000048545|Vega:OTTHUMG00000014696 +2979 GUCA1B MIM:602275|HGNC:HGNC:4679|Ensembl:ENSG00000112599|Vega:OTTHUMG00000014697 +2980 GUCA2A MIM:139392|HGNC:HGNC:4682|Ensembl:ENSG00000197273|Vega:OTTHUMG00000007023 +2981 GUCA2B MIM:601271|HGNC:HGNC:4683|Ensembl:ENSG00000044012|Vega:OTTHUMG00000007024 +2982 GUCY1A3 MIM:139396|HGNC:HGNC:4685|Ensembl:ENSG00000164116|Vega:OTTHUMG00000161700 +2983 GUCY1B3 MIM:139397|HGNC:HGNC:4687|Ensembl:ENSG00000061918|Vega:OTTHUMG00000161698 +2984 GUCY2C MIM:601330|HGNC:HGNC:4688|Ensembl:ENSG00000070019|Vega:OTTHUMG00000168732 +2986 GUCY2F MIM:300041|HGNC:HGNC:4691|Ensembl:ENSG00000101890|Vega:OTTHUMG00000022184 +2987 GUK1 MIM:139270|HGNC:HGNC:4693|Ensembl:ENSG00000143774|Vega:OTTHUMG00000039503 +2988 GUK2 MIM:139280|HGNC:HGNC:4694 +2989 GULOP MIM:240400|HGNC:HGNC:4695 +2990 GUSB MIM:611499|HGNC:HGNC:4696|Ensembl:ENSG00000169919|Vega:OTTHUMG00000023735 +2992 GYG1 MIM:603942|HGNC:HGNC:4699|Ensembl:ENSG00000163754|Vega:OTTHUMG00000159533 +2993 GYPA MIM:111300|HGNC:HGNC:4702|Ensembl:ENSG00000170180|Vega:OTTHUMG00000161403 +2994 GYPB MIM:111740|HGNC:HGNC:4703|Ensembl:ENSG00000250361|Vega:OTTHUMG00000161404 +2995 GYPC MIM:110750|HGNC:HGNC:4704|Ensembl:ENSG00000136732|Vega:OTTHUMG00000131464 +2996 GYPE MIM:138590|HGNC:HGNC:4705|Ensembl:ENSG00000197465|Vega:OTTHUMG00000161402 +2997 GYS1 MIM:138570|HGNC:HGNC:4706|Ensembl:ENSG00000104812|Vega:OTTHUMG00000150723 +2998 GYS2 MIM:138571|HGNC:HGNC:4707|Ensembl:ENSG00000111713|Vega:OTTHUMG00000169135 +2999 GZMH MIM:116831|HGNC:HGNC:4710|Ensembl:ENSG00000100450|Vega:OTTHUMG00000140185 +3000 GUCY2D MIM:600179|HGNC:HGNC:4689|Ensembl:ENSG00000132518|Vega:OTTHUMG00000108169 +3001 GZMA MIM:140050|HGNC:HGNC:4708|Ensembl:ENSG00000145649|Vega:OTTHUMG00000097011 +3002 GZMB MIM:123910|HGNC:HGNC:4709|Ensembl:ENSG00000100453|Vega:OTTHUMG00000029369 +3003 GZMK MIM:600784|HGNC:HGNC:4711|Ensembl:ENSG00000113088|Vega:OTTHUMG00000097009 +3004 GZMM MIM:600311|HGNC:HGNC:4712|Ensembl:ENSG00000197540|Vega:OTTHUMG00000180559 +3005 H1F0 MIM:142708|HGNC:HGNC:4714|Ensembl:ENSG00000189060|Vega:OTTHUMG00000150659 +3006 HIST1H1C MIM:142710|HGNC:HGNC:4716|Ensembl:ENSG00000187837|Vega:OTTHUMG00000016140 +3007 HIST1H1D MIM:142210|HGNC:HGNC:4717|Ensembl:ENSG00000124575|Vega:OTTHUMG00000014432 +3008 HIST1H1E MIM:142220|HGNC:HGNC:4718|Ensembl:ENSG00000168298|Vega:OTTHUMG00000014422 +3009 HIST1H1B MIM:142711|HGNC:HGNC:4719|Ensembl:ENSG00000184357|Vega:OTTHUMG00000016139 +3010 HIST1H1T MIM:142712|HGNC:HGNC:4720|Ensembl:ENSG00000187475|Vega:OTTHUMG00000014430 +3012 HIST1H2AE MIM:602786|HGNC:HGNC:4724|Ensembl:ENSG00000277075|Vega:OTTHUMG00000014440 +3013 HIST1H2AD MIM:602792|HGNC:HGNC:4729|Ensembl:ENSG00000196866|Vega:OTTHUMG00000014437 +3014 H2AFX MIM:601772|HGNC:HGNC:4739|Ensembl:ENSG00000188486|Vega:OTTHUMG00000166196 +3015 H2AFZ MIM:142763|HGNC:HGNC:4741|Ensembl:ENSG00000164032|Vega:OTTHUMG00000131048 +3017 HIST1H2BD MIM:602799|HGNC:HGNC:4747|Ensembl:ENSG00000158373|Vega:OTTHUMG00000014426 +3018 HIST1H2BB MIM:602803|HGNC:HGNC:4751|Ensembl:ENSG00000276410|Vega:OTTHUMG00000014421 +3020 H3F3A MIM:601128|HGNC:HGNC:4764|Ensembl:ENSG00000163041|Vega:OTTHUMG00000037507 +3021 H3F3B MIM:601058|HGNC:HGNC:4765|Ensembl:ENSG00000132475|Vega:OTTHUMG00000179842 +3024 HIST1H1A MIM:142709|HGNC:HGNC:4715|Ensembl:ENSG00000124610|Vega:OTTHUMG00000016413 +3026 HABP2 MIM:603924|HGNC:HGNC:4798|Ensembl:ENSG00000148702|Vega:OTTHUMG00000019073 +3028 HSD17B10 MIM:300256|HGNC:HGNC:4800|Ensembl:ENSG00000072506|Vega:OTTHUMG00000021612 +3029 HAGH MIM:138760|HGNC:HGNC:4805|Ensembl:ENSG00000063854|Vega:OTTHUMG00000128662 +3030 HADHA MIM:600890|HGNC:HGNC:4801|Ensembl:ENSG00000084754|Vega:OTTHUMG00000096979 +3031 HADHAP1 HGNC:HGNC:4802 +3032 HADHB MIM:143450|HGNC:HGNC:4803|Ensembl:ENSG00000138029|Vega:OTTHUMG00000096978 +3033 HADH MIM:601609|HGNC:HGNC:4799|Ensembl:ENSG00000138796|Vega:OTTHUMG00000131810 +3034 HAL MIM:609457|HGNC:HGNC:4806|Ensembl:ENSG00000084110|Vega:OTTHUMG00000170354 +3035 HARS MIM:142810|HGNC:HGNC:4816|Ensembl:ENSG00000170445|Vega:OTTHUMG00000129502 +3036 HAS1 MIM:601463|HGNC:HGNC:4818|Ensembl:ENSG00000105509|Vega:OTTHUMG00000183499 +3037 HAS2 MIM:601636|HGNC:HGNC:4819|Ensembl:ENSG00000170961|Vega:OTTHUMG00000164953 +3038 HAS3 MIM:602428|HGNC:HGNC:4820|Ensembl:ENSG00000103044|Vega:OTTHUMG00000137562 +3039 HBA1 MIM:141800|HGNC:HGNC:4823|Ensembl:ENSG00000206172|Vega:OTTHUMG00000060138 +3040 HBA2 MIM:141850|HGNC:HGNC:4824|Ensembl:ENSG00000188536|Vega:OTTHUMG00000059924 +3041 HBAP1 HGNC:HGNC:4825 +3042 HBM MIM:609639|HGNC:HGNC:4826|Ensembl:ENSG00000206177|Vega:OTTHUMG00000059926 +3043 HBB MIM:141900|HGNC:HGNC:4827|Ensembl:ENSG00000244734|Vega:OTTHUMG00000066678 +3044 HBBP1 HGNC:HGNC:4828 +3045 HBD MIM:142000|HGNC:HGNC:4829|Ensembl:ENSG00000223609|Vega:OTTHUMG00000066674 +3046 HBE1 MIM:142100|HGNC:HGNC:4830|Ensembl:ENSG00000213931|Vega:OTTHUMG00000066675 +3047 HBG1 MIM:142200|HGNC:HGNC:4831|Ensembl:ENSG00000213934|Vega:OTTHUMG00000066681 +3048 HBG2 MIM:142250|HGNC:HGNC:4832|Ensembl:ENSG00000196565|Vega:OTTHUMG00000066673 +3049 HBQ1 MIM:142240|HGNC:HGNC:4833|Ensembl:ENSG00000086506|Vega:OTTHUMG00000060727 +3050 HBZ MIM:142310|HGNC:HGNC:4835|Ensembl:ENSG00000130656|Vega:OTTHUMG00000059928 +3051 HBZP1 HGNC:HGNC:4836 +3052 HCCS MIM:300056|HGNC:HGNC:4837|Ensembl:ENSG00000004961|Vega:OTTHUMG00000021128 +3053 SERPIND1 MIM:142360|HGNC:HGNC:4838|Ensembl:ENSG00000099937|Vega:OTTHUMG00000150755 +3054 HCFC1 MIM:300019|HGNC:HGNC:4839|Ensembl:ENSG00000172534|Vega:OTTHUMG00000024222 +3055 HCK MIM:142370|HGNC:HGNC:4840|Ensembl:ENSG00000101336|Vega:OTTHUMG00000032204 +3056 HCL1 HGNC:HGNC:4841 +3057 HCL2 MIM:266300|HGNC:HGNC:4842 +3059 HCLS1 MIM:601306|HGNC:HGNC:4844|Ensembl:ENSG00000180353|Vega:OTTHUMG00000159409 +3060 HCRT MIM:602358|HGNC:HGNC:4847|Ensembl:ENSG00000161610|Vega:OTTHUMG00000180107 +3061 HCRTR1 MIM:602392|HGNC:HGNC:4848|Ensembl:ENSG00000121764|Vega:OTTHUMG00000003876 +3062 HCRTR2 MIM:602393|HGNC:HGNC:4849|Ensembl:ENSG00000137252|Vega:OTTHUMG00000016150 +3063 HCVS MIM:122460|HGNC:HGNC:4850 +3064 HTT MIM:613004|HGNC:HGNC:4851|Ensembl:ENSG00000197386|Vega:OTTHUMG00000159916 +3065 HDAC1 MIM:601241|HGNC:HGNC:4852|Ensembl:ENSG00000116478|Vega:OTTHUMG00000007529 +3066 HDAC2 MIM:605164|HGNC:HGNC:4853|Ensembl:ENSG00000196591|Vega:OTTHUMG00000015411 +3067 HDC MIM:142704|HGNC:HGNC:4855|Ensembl:ENSG00000140287|Vega:OTTHUMG00000131644 +3068 HDGF MIM:600339|HGNC:HGNC:4856|Ensembl:ENSG00000143321|Vega:OTTHUMG00000041295 +3069 HDLBP MIM:142695|HGNC:HGNC:4857|Ensembl:ENSG00000115677|Vega:OTTHUMG00000133391 +3070 HELLS MIM:603946|HGNC:HGNC:4861|Ensembl:ENSG00000119969|Vega:OTTHUMG00000018793 +3071 NCKAP1L MIM:141180|HGNC:HGNC:4862|Ensembl:ENSG00000123338|Vega:OTTHUMG00000169843 +3073 HEXA MIM:606869|HGNC:HGNC:4878|Ensembl:ENSG00000213614|Vega:OTTHUMG00000133445 +3074 HEXB MIM:606873|HGNC:HGNC:4879|Ensembl:ENSG00000049860|Vega:OTTHUMG00000102057 +3075 CFH MIM:134370|HGNC:HGNC:4883|Ensembl:ENSG00000000971|Vega:OTTHUMG00000035607 +3077 HFE MIM:613609|HGNC:HGNC:4886|Ensembl:ENSG00000010704|Vega:OTTHUMG00000016348 +3078 CFHR1 MIM:134371|HGNC:HGNC:4888|Ensembl:ENSG00000244414|Vega:OTTHUMG00000036276 +3080 CFHR2 MIM:600889|HGNC:HGNC:4890|Ensembl:ENSG00000080910|Ensembl:ENSG00000276911|Vega:OTTHUMG00000036518|Vega:OTTHUMG00000186748 +3081 HGD MIM:607474|HGNC:HGNC:4892|Ensembl:ENSG00000113924|Vega:OTTHUMG00000159441 +3082 HGF MIM:142409|HGNC:HGNC:4893|Ensembl:ENSG00000019991|Vega:OTTHUMG00000023804 +3083 HGFAC MIM:604552|HGNC:HGNC:4894|Ensembl:ENSG00000109758|Vega:OTTHUMG00000090281 +3084 NRG1 MIM:142445|HGNC:HGNC:7997|Ensembl:ENSG00000157168|Vega:OTTHUMG00000163918 +3087 HHEX MIM:604420|HGNC:HGNC:4901|Ensembl:ENSG00000152804|Vega:OTTHUMG00000018762 +3090 HIC1 MIM:603825|HGNC:HGNC:4909|Ensembl:ENSG00000177374|Vega:OTTHUMG00000177635 +3091 HIF1A MIM:603348|HGNC:HGNC:4910|Ensembl:ENSG00000100644|Vega:OTTHUMG00000140344 +3092 HIP1 MIM:601767|HGNC:HGNC:4913|Ensembl:ENSG00000127946|Vega:OTTHUMG00000156050 +3093 UBE2K MIM:602846|HGNC:HGNC:4914|Ensembl:ENSG00000078140|Vega:OTTHUMG00000160543 +3094 HINT1 MIM:601314|HGNC:HGNC:4912|Ensembl:ENSG00000169567|Vega:OTTHUMG00000128995 +3096 HIVEP1 MIM:194540|HGNC:HGNC:4920|Ensembl:ENSG00000095951|Vega:OTTHUMG00000014265 +3097 HIVEP2 MIM:143054|HGNC:HGNC:4921|Ensembl:ENSG00000010818|Vega:OTTHUMG00000015713 +3098 HK1 MIM:142600|HGNC:HGNC:4922|Ensembl:ENSG00000156515|Vega:OTTHUMG00000018380 +3099 HK2 MIM:601125|HGNC:HGNC:4923|Ensembl:ENSG00000159399|Vega:OTTHUMG00000129972 +3101 HK3 MIM:142570|HGNC:HGNC:4925|Ensembl:ENSG00000160883|Vega:OTTHUMG00000130855 +3104 ZBTB48 MIM:165270|HGNC:HGNC:4930|Ensembl:ENSG00000204859|Vega:OTTHUMG00000001438 +3105 HLA-A MIM:142800|HGNC:HGNC:4931|Ensembl:ENSG00000206503|Vega:OTTHUMG00000130501 +3106 HLA-B MIM:142830|HGNC:HGNC:4932|Ensembl:ENSG00000234745|Vega:OTTHUMG00000031153 +3107 HLA-C MIM:142840|HGNC:HGNC:4933|Ensembl:ENSG00000204525|Vega:OTTHUMG00000031154 +3108 HLA-DMA MIM:142855|HGNC:HGNC:4934|Ensembl:ENSG00000204257|Vega:OTTHUMG00000031173 +3109 HLA-DMB MIM:142856|HGNC:HGNC:4935|Ensembl:ENSG00000242574|Vega:OTTHUMG00000031176 +3110 MNX1 MIM:142994|HGNC:HGNC:4979|Ensembl:ENSG00000130675|Vega:OTTHUMG00000157181 +3111 HLA-DOA MIM:142930|HGNC:HGNC:4936|Ensembl:ENSG00000204252|Vega:OTTHUMG00000031211 +3112 HLA-DOB MIM:600629|HGNC:HGNC:4937|Ensembl:ENSG00000241106|Vega:OTTHUMG00000031213 +3113 HLA-DPA1 MIM:142880|HGNC:HGNC:4938|Ensembl:ENSG00000231389|Vega:OTTHUMG00000031058 +3115 HLA-DPB1 MIM:142858|HGNC:HGNC:4940|Ensembl:ENSG00000223865|Vega:OTTHUMG00000031076 +3116 HLA-DPB2 HGNC:HGNC:4941|Ensembl:ENSG00000224557 +3117 HLA-DQA1 MIM:146880|HGNC:HGNC:4942|Ensembl:ENSG00000196735|Vega:OTTHUMG00000031106 +3118 HLA-DQA2 MIM:613503|HGNC:HGNC:4943|Ensembl:ENSG00000237541|Vega:OTTHUMG00000031108 +3119 HLA-DQB1 MIM:604305|HGNC:HGNC:4944|Ensembl:ENSG00000179344|Vega:OTTHUMG00000031124 +3120 HLA-DQB2 MIM:615161|HGNC:HGNC:4945|Ensembl:ENSG00000232629|Vega:OTTHUMG00000031125 +3121 HLA-DQB3 HGNC:HGNC:4946 +3122 HLA-DRA MIM:142860|HGNC:HGNC:4947|Ensembl:ENSG00000204287|Vega:OTTHUMG00000031269 +3123 HLA-DRB1 MIM:142857|HGNC:HGNC:4948|Ensembl:ENSG00000196126|Vega:OTTHUMG00000031196 +3124 HLA-DRB2 HGNC:HGNC:4950 +3125 HLA-DRB3 MIM:612735|HGNC:HGNC:4951 +3126 HLA-DRB4 HGNC:HGNC:4952 +3127 HLA-DRB5 MIM:604776|HGNC:HGNC:4953|Ensembl:ENSG00000198502|Vega:OTTHUMG00000031027 +3128 HLA-DRB6 HGNC:HGNC:4954|Ensembl:ENSG00000229391 +3129 HLA-DRB7 HGNC:HGNC:4955 +3130 HLA-DRB8 HGNC:HGNC:4956 +3131 HLF MIM:142385|HGNC:HGNC:4977|Ensembl:ENSG00000108924|Vega:OTTHUMG00000177840 +3132 HLA-DRB9 HGNC:HGNC:4957 +3133 HLA-E MIM:143010|HGNC:HGNC:4962|Ensembl:ENSG00000204592|Vega:OTTHUMG00000031155 +3134 HLA-F MIM:143110|HGNC:HGNC:4963|Ensembl:ENSG00000204642|Vega:OTTHUMG00000031156 +3135 HLA-G MIM:142871|HGNC:HGNC:4964|Ensembl:ENSG00000204632|Vega:OTTHUMG00000031157 +3136 HLA-H HGNC:HGNC:4965 +3137 HLA-J HGNC:HGNC:4967|Ensembl:ENSG00000204622 +3138 HLA-K HGNC:HGNC:4969 +3139 HLA-L HGNC:HGNC:4970|Ensembl:ENSG00000243753 +3140 MR1 MIM:600764|HGNC:HGNC:4975|Ensembl:ENSG00000153029|Vega:OTTHUMG00000035175 +3141 HLCS MIM:609018|HGNC:HGNC:4976|Ensembl:ENSG00000159267|Vega:OTTHUMG00000086636 +3142 HLX MIM:142995|HGNC:HGNC:4978|Ensembl:ENSG00000136630|Vega:OTTHUMG00000037352 +3145 HMBS MIM:609806|HGNC:HGNC:4982|Ensembl:ENSG00000256269|Vega:OTTHUMG00000168295 +3146 HMGB1 MIM:163905|HGNC:HGNC:4983|Ensembl:ENSG00000189403|Vega:OTTHUMG00000016670 +3148 HMGB2 MIM:163906|HGNC:HGNC:5000|Ensembl:ENSG00000164104|Vega:OTTHUMG00000160799 +3149 HMGB3 MIM:300193|HGNC:HGNC:5004|Ensembl:ENSG00000029993|Vega:OTTHUMG00000024162 +3150 HMGN1 MIM:163920|HGNC:HGNC:4984|Ensembl:ENSG00000205581|Vega:OTTHUMG00000066178 +3151 HMGN2 MIM:163910|HGNC:HGNC:4986|Ensembl:ENSG00000198830|Vega:OTTHUMG00000003555 +3152 HMGN2P11 HGNC:HGNC:4990 +3153 HMGN2P12 HGNC:HGNC:4991 +3155 HMGCL MIM:613898|HGNC:HGNC:5005|Ensembl:ENSG00000117305|Vega:OTTHUMG00000002963 +3156 HMGCR MIM:142910|HGNC:HGNC:5006|Ensembl:ENSG00000113161|Vega:OTTHUMG00000102069 +3157 HMGCS1 MIM:142940|HGNC:HGNC:5007|Ensembl:ENSG00000112972|Vega:OTTHUMG00000162231 +3158 HMGCS2 MIM:600234|HGNC:HGNC:5008|Ensembl:ENSG00000134240|Vega:OTTHUMG00000012101 +3159 HMGA1 MIM:600701|HGNC:HGNC:5010|Ensembl:ENSG00000137309|Vega:OTTHUMG00000014539 +3161 HMMR MIM:600936|HGNC:HGNC:5012|Ensembl:ENSG00000072571|Vega:OTTHUMG00000130381 +3162 HMOX1 MIM:141250|HGNC:HGNC:5013|Ensembl:ENSG00000100292|Vega:OTTHUMG00000150960 +3163 HMOX2 MIM:141251|HGNC:HGNC:5014|Ensembl:ENSG00000103415|Vega:OTTHUMG00000129473 +3164 NR4A1 MIM:139139|HGNC:HGNC:7980|Ensembl:ENSG00000123358|Vega:OTTHUMG00000150393 +3166 HMX1 MIM:142992|HGNC:HGNC:5017|Ensembl:ENSG00000215612|Vega:OTTHUMG00000160012 +3167 HMX2 MIM:600647|HGNC:HGNC:5018|Ensembl:ENSG00000188816|Vega:OTTHUMG00000019198 +3169 FOXA1 MIM:602294|HGNC:HGNC:5021|Ensembl:ENSG00000129514|Vega:OTTHUMG00000140253 +3170 FOXA2 MIM:600288|HGNC:HGNC:5022|Ensembl:ENSG00000125798|Vega:OTTHUMG00000191876 +3171 FOXA3 MIM:602295|HGNC:HGNC:5023|Ensembl:ENSG00000170608|Vega:OTTHUMG00000182484 +3172 HNF4A MIM:600281|HGNC:HGNC:5024|Ensembl:ENSG00000101076|Vega:OTTHUMG00000032531 +3174 HNF4G MIM:605966|HGNC:HGNC:5026|Ensembl:ENSG00000164749|Vega:OTTHUMG00000149920 +3175 ONECUT1 MIM:604164|HGNC:HGNC:8138|Ensembl:ENSG00000169856|Vega:OTTHUMG00000131899 +3176 HNMT MIM:605238|HGNC:HGNC:5028|Ensembl:ENSG00000150540|Vega:OTTHUMG00000131751 +3177 SLC29A2 MIM:602110|HGNC:HGNC:11004|Ensembl:ENSG00000174669|Vega:OTTHUMG00000169056 +3178 HNRNPA1 MIM:164017|HGNC:HGNC:5031|Ensembl:ENSG00000135486|Vega:OTTHUMG00000169702 +3181 HNRNPA2B1 MIM:600124|HGNC:HGNC:5033|Ensembl:ENSG00000122566|Vega:OTTHUMG00000023471 +3182 HNRNPAB MIM:602688|HGNC:HGNC:5034|Ensembl:ENSG00000197451|Vega:OTTHUMG00000163452 +3183 HNRNPC MIM:164020|HGNC:HGNC:5035|Ensembl:ENSG00000092199|Vega:OTTHUMG00000170757 +3184 HNRNPD MIM:601324|HGNC:HGNC:5036|Ensembl:ENSG00000138668|Vega:OTTHUMG00000130290 +3185 HNRNPF MIM:601037|HGNC:HGNC:5039|Ensembl:ENSG00000169813|Vega:OTTHUMG00000018029 +3186 RBMXP1 HGNC:HGNC:9911 +3187 HNRNPH1 MIM:601035|HGNC:HGNC:5041|Ensembl:ENSG00000169045|Vega:OTTHUMG00000130908 +3188 HNRNPH2 MIM:300610|HGNC:HGNC:5042|Ensembl:ENSG00000126945|Vega:OTTHUMG00000022029 +3189 HNRNPH3 MIM:602324|HGNC:HGNC:5043|Ensembl:ENSG00000096746|Vega:OTTHUMG00000018349 +3190 HNRNPK MIM:600712|HGNC:HGNC:5044|Ensembl:ENSG00000165119|Vega:OTTHUMG00000020107 +3191 HNRNPL MIM:603083|HGNC:HGNC:5045|Ensembl:ENSG00000104824|Vega:OTTHUMG00000182612 +3192 HNRNPU MIM:602869|HGNC:HGNC:5048|Ensembl:ENSG00000153187|Vega:OTTHUMG00000040396 +3193 HOAC HGNC:HGNC:5049 +3195 TLX1 MIM:186770|HGNC:HGNC:5056|Ensembl:ENSG00000107807|Vega:OTTHUMG00000019341 +3196 TLX2 MIM:604240|HGNC:HGNC:5057|Ensembl:ENSG00000115297|Vega:OTTHUMG00000129960 +3197 HOXA@ HGNC:HGNC:5098 +3198 HOXA1 MIM:142955|HGNC:HGNC:5099|Ensembl:ENSG00000105991|Vega:OTTHUMG00000023207 +3199 HOXA2 MIM:604685|HGNC:HGNC:5103|Ensembl:ENSG00000105996|Vega:OTTHUMG00000023208 +3200 HOXA3 MIM:142954|HGNC:HGNC:5104|Ensembl:ENSG00000105997|Vega:OTTHUMG00000023209 +3201 HOXA4 MIM:142953|HGNC:HGNC:5105|Ensembl:ENSG00000197576|Vega:OTTHUMG00000023213 +3202 HOXA5 MIM:142952|HGNC:HGNC:5106|Ensembl:ENSG00000106004|Vega:OTTHUMG00000023214 +3203 HOXA6 MIM:142951|HGNC:HGNC:5107|Ensembl:ENSG00000106006|Vega:OTTHUMG00000023216 +3204 HOXA7 MIM:142950|HGNC:HGNC:5108|Ensembl:ENSG00000122592|Vega:OTTHUMG00000023217 +3205 HOXA9 MIM:142956|HGNC:HGNC:5109|Ensembl:ENSG00000078399|Vega:OTTHUMG00000023220 +3206 HOXA10 MIM:142957|HGNC:HGNC:5100|Ensembl:ENSG00000253293|Vega:OTTHUMG00000023436 +3207 HOXA11 MIM:142958|HGNC:HGNC:5101|Ensembl:ENSG00000005073|Vega:OTTHUMG00000023437 +3208 HPCA MIM:142622|HGNC:HGNC:5144|Ensembl:ENSG00000121905|Vega:OTTHUMG00000004017 +3209 HOXA13 MIM:142959|HGNC:HGNC:5102|Ensembl:ENSG00000106031|Vega:OTTHUMG00000023438 +3210 HOXB@ HGNC:HGNC:5110 +3211 HOXB1 MIM:142968|HGNC:HGNC:5111|Ensembl:ENSG00000120094|Vega:OTTHUMG00000159929 +3212 HOXB2 MIM:142967|HGNC:HGNC:5113|Ensembl:ENSG00000173917|Vega:OTTHUMG00000159930 +3213 HOXB3 MIM:142966|HGNC:HGNC:5114|Ensembl:ENSG00000120093|Vega:OTTHUMG00000159922 +3214 HOXB4 MIM:142965|HGNC:HGNC:5115|Ensembl:ENSG00000182742|Vega:OTTHUMG00000159920 +3215 HOXB5 MIM:142960|HGNC:HGNC:5116|Ensembl:ENSG00000120075|Vega:OTTHUMG00000159913 +3216 HOXB6 MIM:142961|HGNC:HGNC:5117|Ensembl:ENSG00000108511|Vega:OTTHUMG00000159912 +3217 HOXB7 MIM:142962|HGNC:HGNC:5118|Ensembl:ENSG00000260027|Vega:OTTHUMG00000170231 +3218 HOXB8 MIM:142963|HGNC:HGNC:5119|Ensembl:ENSG00000120068|Vega:OTTHUMG00000159904 +3219 HOXB9 MIM:142964|HGNC:HGNC:5120|Ensembl:ENSG00000170689|Vega:OTTHUMG00000159907 +3220 HOXC@ HGNC:HGNC:5121 +3221 HOXC4 MIM:142974|HGNC:HGNC:5126|Ensembl:ENSG00000198353|Vega:OTTHUMG00000160036 +3222 HOXC5 MIM:142973|HGNC:HGNC:5127|Ensembl:ENSG00000172789|Ensembl:ENSG00000273046|Vega:OTTHUMG00000160028 +3223 HOXC6 MIM:142972|HGNC:HGNC:5128|Ensembl:ENSG00000197757|Vega:OTTHUMG00000160027 +3224 HOXC8 MIM:142970|HGNC:HGNC:5129|Ensembl:ENSG00000037965|Vega:OTTHUMG00000160032 +3225 HOXC9 MIM:142971|HGNC:HGNC:5130|Ensembl:ENSG00000180806|Vega:OTTHUMG00000160033 +3226 HOXC10 MIM:605560|HGNC:HGNC:5122|Ensembl:ENSG00000180818|Vega:OTTHUMG00000160031 +3227 HOXC11 MIM:605559|HGNC:HGNC:5123|Ensembl:ENSG00000123388|Vega:OTTHUMG00000160011 +3228 HOXC12 MIM:142975|HGNC:HGNC:5124|Ensembl:ENSG00000123407|Vega:OTTHUMG00000160010 +3229 HOXC13 MIM:142976|HGNC:HGNC:5125|Ensembl:ENSG00000123364|Vega:OTTHUMG00000160008 +3230 HOXD@ HGNC:HGNC:5131 +3231 HOXD1 MIM:142987|HGNC:HGNC:5132|Ensembl:ENSG00000128645|Vega:OTTHUMG00000132512 +3232 HOXD3 MIM:142980|HGNC:HGNC:5137|Ensembl:ENSG00000128652|Vega:OTTHUMG00000187566 +3233 HOXD4 MIM:142981|HGNC:HGNC:5138|Ensembl:ENSG00000170166|Ensembl:ENSG00000278500|Vega:OTTHUMG00000132515|Vega:OTTHUMG00000132517 +3234 HOXD8 MIM:142985|HGNC:HGNC:5139|Ensembl:ENSG00000175879|Vega:OTTHUMG00000132513 +3235 HOXD9 MIM:142982|HGNC:HGNC:5140|Ensembl:ENSG00000128709|Vega:OTTHUMG00000132516 +3236 HOXD10 MIM:142984|HGNC:HGNC:5133|Ensembl:ENSG00000128710|Vega:OTTHUMG00000132511 +3237 HOXD11 MIM:142986|HGNC:HGNC:5134|Ensembl:ENSG00000128713|Vega:OTTHUMG00000132510 +3238 HOXD12 MIM:142988|HGNC:HGNC:5135|Ensembl:ENSG00000170178|Vega:OTTHUMG00000150358 +3239 HOXD13 MIM:142989|HGNC:HGNC:5136|Ensembl:ENSG00000128714|Vega:OTTHUMG00000132431 +3240 HP MIM:140100|HGNC:HGNC:5141|Ensembl:ENSG00000257017|Vega:OTTHUMG00000173009 +3241 HPCAL1 MIM:600207|HGNC:HGNC:5145|Ensembl:ENSG00000115756|Vega:OTTHUMG00000090451 +3242 HPD MIM:609695|HGNC:HGNC:5147|Ensembl:ENSG00000158104|Vega:OTTHUMG00000169081 +3244 HPE1 MIM:236100|HGNC:HGNC:5149 +3247 HPFH2 MIM:142335|HGNC:HGNC:5153 +3248 HPGD MIM:601688|HGNC:HGNC:5154|Ensembl:ENSG00000164120|Vega:OTTHUMG00000160772 +3249 HPN MIM:142440|HGNC:HGNC:5155|Ensembl:ENSG00000105707|Vega:OTTHUMG00000182474 +3250 HPR MIM:140210|HGNC:HGNC:5156|Ensembl:ENSG00000261701|Vega:OTTHUMG00000173010 +3251 HPRT1 MIM:308000|HGNC:HGNC:5157|Ensembl:ENSG00000165704|Vega:OTTHUMG00000022452 +3254 HPRT1P2 HGNC:HGNC:5160 +3255 HPRT1P3 HGNC:HGNC:5161 +3257 HPS1 MIM:604982|HGNC:HGNC:5163|Ensembl:ENSG00000107521|Vega:OTTHUMG00000018876 +3258 HPT MIM:307700|HGNC:HGNC:5165 +3259 HPV6AI1 MIM:604461|HGNC:HGNC:5168 +3260 HPV18I1 MIM:167959|HGNC:HGNC:5166 +3261 HPV18I2 MIM:167960|HGNC:HGNC:5167 +3262 HPVC1 MIM:600762|HGNC:HGNC:5169 +3263 HPX MIM:142290|HGNC:HGNC:5171|Ensembl:ENSG00000110169|Vega:OTTHUMG00000133399 +3265 HRAS MIM:190020|HGNC:HGNC:5173|Ensembl:ENSG00000174775|Vega:OTTHUMG00000131919 +3266 ERAS MIM:300437|HGNC:HGNC:5174|Ensembl:ENSG00000187682|Vega:OTTHUMG00000059533 +3267 AGFG1 MIM:600862|HGNC:HGNC:5175|Ensembl:ENSG00000173744|Vega:OTTHUMG00000133186 +3268 AGFG2 MIM:604019|HGNC:HGNC:5177|Ensembl:ENSG00000106351|Vega:OTTHUMG00000156029 +3269 HRH1 MIM:600167|HGNC:HGNC:5182|Ensembl:ENSG00000196639|Vega:OTTHUMG00000129719 +3270 HRC MIM:142705|HGNC:HGNC:5178|Ensembl:ENSG00000130528|Vega:OTTHUMG00000183203 +3272 HRES1 MIM:143025|HGNC:HGNC:5180 +3273 HRG MIM:142640|HGNC:HGNC:5181|Ensembl:ENSG00000113905|Vega:OTTHUMG00000156578 +3274 HRH2 MIM:142703|HGNC:HGNC:5183|Ensembl:ENSG00000113749|Vega:OTTHUMG00000130660 +3275 PRMT2 MIM:601961|HGNC:HGNC:5186|Ensembl:ENSG00000160310|Vega:OTTHUMG00000048806 +3276 PRMT1 MIM:602950|HGNC:HGNC:5187|Ensembl:ENSG00000126457|Vega:OTTHUMG00000167568 +3280 HES1 MIM:139605|HGNC:HGNC:5192|Ensembl:ENSG00000114315|Vega:OTTHUMG00000155984 +3281 HSBP1 MIM:604553|HGNC:HGNC:5203|Ensembl:ENSG00000230989|Vega:OTTHUMG00000176653 +3283 HSD3B1 MIM:109715|HGNC:HGNC:5217|Ensembl:ENSG00000203857|Vega:OTTHUMG00000012525 +3284 HSD3B2 MIM:613890|HGNC:HGNC:5218|Ensembl:ENSG00000203859|Vega:OTTHUMG00000012526 +3290 HSD11B1 MIM:600713|HGNC:HGNC:5208|Ensembl:ENSG00000117594|Vega:OTTHUMG00000036481 +3291 HSD11B2 MIM:614232|HGNC:HGNC:5209|Ensembl:ENSG00000176387|Vega:OTTHUMG00000137507 +3292 HSD17B1 MIM:109684|HGNC:HGNC:5210|Ensembl:ENSG00000108786|Vega:OTTHUMG00000180243 +3293 HSD17B3 MIM:605573|HGNC:HGNC:5212|Ensembl:ENSG00000130948|Vega:OTTHUMG00000020292 +3294 HSD17B2 MIM:109685|HGNC:HGNC:5211|Ensembl:ENSG00000086696|Vega:OTTHUMG00000137631 +3295 HSD17B4 MIM:601860|HGNC:HGNC:5213|Ensembl:ENSG00000133835|Vega:OTTHUMG00000128899 +3297 HSF1 MIM:140580|HGNC:HGNC:5224|Ensembl:ENSG00000185122|Vega:OTTHUMG00000174604 +3298 HSF2 MIM:140581|HGNC:HGNC:5225|Ensembl:ENSG00000025156|Vega:OTTHUMG00000016216 +3299 HSF4 MIM:602438|HGNC:HGNC:5227|Ensembl:ENSG00000102878|Vega:OTTHUMG00000178325 +3300 DNAJB2 MIM:604139|HGNC:HGNC:5228|Ensembl:ENSG00000135924|Vega:OTTHUMG00000133134 +3301 DNAJA1 MIM:602837|HGNC:HGNC:5229|Ensembl:ENSG00000086061|Vega:OTTHUMG00000019760 +3303 HSPA1A MIM:140550|HGNC:HGNC:5232|Ensembl:ENSG00000204389|Vega:OTTHUMG00000031201 +3304 HSPA1B MIM:603012|HGNC:HGNC:5233|Ensembl:ENSG00000204388|Vega:OTTHUMG00000031202 +3305 HSPA1L MIM:140559|HGNC:HGNC:5234|Ensembl:ENSG00000204390|Vega:OTTHUMG00000031208 +3306 HSPA2 MIM:140560|HGNC:HGNC:5235|Ensembl:ENSG00000126803|Vega:OTTHUMG00000141311 +3308 HSPA4 MIM:601113|HGNC:HGNC:5237|Ensembl:ENSG00000170606|Vega:OTTHUMG00000129012 +3309 HSPA5 MIM:138120|HGNC:HGNC:5238|Ensembl:ENSG00000044574|Vega:OTTHUMG00000020672 +3310 HSPA6 MIM:140555|HGNC:HGNC:5239|Ensembl:ENSG00000173110|Vega:OTTHUMG00000034461 +3311 HSPA7 MIM:140556|HGNC:HGNC:5240 +3312 HSPA8 MIM:600816|HGNC:HGNC:5241|Ensembl:ENSG00000109971|Vega:OTTHUMG00000166030 +3313 HSPA9 MIM:600548|HGNC:HGNC:5244|Ensembl:ENSG00000113013|Vega:OTTHUMG00000129206 +3314 HSPA8P1 HGNC:HGNC:5245 +3315 HSPB1 MIM:602195|HGNC:HGNC:5246|Ensembl:ENSG00000106211|Vega:OTTHUMG00000023228 +3316 HSPB2 MIM:602179|HGNC:HGNC:5247|Ensembl:ENSG00000170276|Ensembl:ENSG00000254445|Vega:OTTHUMG00000166886|Vega:OTTHUMG00000166887 +3320 HSP90AA1 MIM:140571|HGNC:HGNC:5253|Ensembl:ENSG00000080824|Vega:OTTHUMG00000171752 +3321 IGSF3 MIM:603491|HGNC:HGNC:5950|Ensembl:ENSG00000143061|Vega:OTTHUMG00000022751 +3322 HSP90AA3P HGNC:HGNC:5254 +3323 HSP90AA4P HGNC:HGNC:5255 +3324 HSP90AA2P MIM:140575|HGNC:HGNC:5256 +3326 HSP90AB1 MIM:140572|HGNC:HGNC:5258|Ensembl:ENSG00000096384|Vega:OTTHUMG00000014761 +3327 HSP90AB3P HGNC:HGNC:5259 +3329 HSPD1 MIM:118190|HGNC:HGNC:5261|Ensembl:ENSG00000144381|Vega:OTTHUMG00000154463 +3332 HSPD1P3 HGNC:HGNC:5264 +3336 HSPE1 MIM:600141|HGNC:HGNC:5269|Ensembl:ENSG00000115541|Vega:OTTHUMG00000132749 +3337 DNAJB1 MIM:604572|HGNC:HGNC:5270|Ensembl:ENSG00000132002|Vega:OTTHUMG00000183289 +3338 DNAJC4 MIM:604189|HGNC:HGNC:5271|Ensembl:ENSG00000110011|Vega:OTTHUMG00000167792 +3339 HSPG2 MIM:142461|HGNC:HGNC:5273|Ensembl:ENSG00000142798|Vega:OTTHUMG00000002674 +3340 NDST1 MIM:600853|HGNC:HGNC:7680|Ensembl:ENSG00000070614|Vega:OTTHUMG00000163572 +3341 HTC1 MIM:145701|HGNC:HGNC:5277 +3342 HTC2 MIM:307150|HGNC:HGNC:5278 +3343 HTL MIM:151310|HGNC:HGNC:5280 +3344 FOXN2 MIM:143089|HGNC:HGNC:5281|Ensembl:ENSG00000170802|Vega:OTTHUMG00000129168 +3346 HTN1 MIM:142701|HGNC:HGNC:5283|Ensembl:ENSG00000126550|Vega:OTTHUMG00000129397 +3347 HTN3 MIM:142702|HGNC:HGNC:5284|Ensembl:ENSG00000205649 +3349 HTOR MIM:143460|HGNC:HGNC:5285 +3350 HTR1A MIM:109760|HGNC:HGNC:5286|Ensembl:ENSG00000178394|Vega:OTTHUMG00000162279 +3351 HTR1B MIM:182131|HGNC:HGNC:5287|Ensembl:ENSG00000135312|Vega:OTTHUMG00000015066 +3352 HTR1D MIM:182133|HGNC:HGNC:5289|Ensembl:ENSG00000179546|Vega:OTTHUMG00000003235 +3354 HTR1E MIM:182132|HGNC:HGNC:5291|Ensembl:ENSG00000168830|Vega:OTTHUMG00000015154 +3355 HTR1F MIM:182134|HGNC:HGNC:5292|Ensembl:ENSG00000179097|Vega:OTTHUMG00000159008 +3356 HTR2A MIM:182135|HGNC:HGNC:5293|Ensembl:ENSG00000102468|Vega:OTTHUMG00000016881 +3357 HTR2B MIM:601122|HGNC:HGNC:5294|Ensembl:ENSG00000135914|Vega:OTTHUMG00000133222 +3358 HTR2C MIM:312861|HGNC:HGNC:5295|Ensembl:ENSG00000147246|Vega:OTTHUMG00000022226 +3359 HTR3A MIM:182139|HGNC:HGNC:5297|Ensembl:ENSG00000166736|Vega:OTTHUMG00000160494 +3360 HTR4 MIM:602164|HGNC:HGNC:5299|Ensembl:ENSG00000164270|Vega:OTTHUMG00000129931 +3361 HTR5A MIM:601305|HGNC:HGNC:5300|Ensembl:ENSG00000157219|Vega:OTTHUMG00000151327 +3362 HTR6 MIM:601109|HGNC:HGNC:5301|Ensembl:ENSG00000158748|Vega:OTTHUMG00000002713 +3363 HTR7 MIM:182137|HGNC:HGNC:5302|Ensembl:ENSG00000148680|Vega:OTTHUMG00000018732 +3364 HUS1 MIM:603760|HGNC:HGNC:5309|Ensembl:ENSG00000136273|Vega:OTTHUMG00000155645 +3369 HVBS7 HGNC:HGNC:5314 +3370 HVBS8 HGNC:HGNC:5315 +3371 TNC MIM:187380|HGNC:HGNC:5318|Ensembl:ENSG00000041982|Vega:OTTHUMG00000021010 +3373 HYAL1 MIM:607071|HGNC:HGNC:5320|Ensembl:ENSG00000114378|Vega:OTTHUMG00000156941 +3375 IAPP MIM:147940|HGNC:HGNC:5329|Ensembl:ENSG00000121351|Vega:OTTHUMG00000169128 +3376 IARS MIM:600709|HGNC:HGNC:5330|Ensembl:ENSG00000196305|Vega:OTTHUMG00000020219 +3378 IBD2 MIM:601458|HGNC:HGNC:5332 +3381 IBSP MIM:147563|HGNC:HGNC:5341|Ensembl:ENSG00000029559|Vega:OTTHUMG00000130600 +3382 ICA1 MIM:147625|HGNC:HGNC:5343|Ensembl:ENSG00000003147|Vega:OTTHUMG00000152008 +3383 ICAM1 MIM:147840|HGNC:HGNC:5344|Ensembl:ENSG00000090339|Vega:OTTHUMG00000180403 +3384 ICAM2 MIM:146630|HGNC:HGNC:5345|Ensembl:ENSG00000108622|Vega:OTTHUMG00000178865 +3385 ICAM3 MIM:146631|HGNC:HGNC:5346|Ensembl:ENSG00000076662|Vega:OTTHUMG00000180410 +3386 ICAM4 MIM:614088|HGNC:HGNC:5347|Ensembl:ENSG00000105371|Vega:OTTHUMG00000180405 +3388 ICR1 HGNC:HGNC:5352 +3390 ICR3 HGNC:HGNC:5354 +3391 ICR4 HGNC:HGNC:5355 +3394 IRF8 MIM:601565|HGNC:HGNC:5358|Ensembl:ENSG00000140968|Vega:OTTHUMG00000137648 +3396 MRPL58 MIM:603000|HGNC:HGNC:5359|Ensembl:ENSG00000167862|Vega:OTTHUMG00000179218 +3397 ID1 MIM:600349|HGNC:HGNC:5360|Ensembl:ENSG00000125968|Vega:OTTHUMG00000032181 +3398 ID2 MIM:600386|HGNC:HGNC:5361|Ensembl:ENSG00000115738|Vega:OTTHUMG00000112454 +3399 ID3 MIM:600277|HGNC:HGNC:5362|Ensembl:ENSG00000117318 +3400 ID4 MIM:600581|HGNC:HGNC:5363|Ensembl:ENSG00000172201|Vega:OTTHUMG00000014333 +3402 IDDM3 MIM:600318|HGNC:HGNC:5374 +3403 IDDM4 MIM:600319|HGNC:HGNC:5375 +3405 IDDM6 MIM:601941|HGNC:HGNC:5377 +3406 IDDM7 MIM:600321|HGNC:HGNC:5378 +3407 IDDM8 MIM:600883|HGNC:HGNC:5379 +3408 IDDM9 HGNC:HGNC:5380 +3410 IDDM11 MIM:601208|HGNC:HGNC:5365 +3412 IDDM13 MIM:601318|HGNC:HGNC:5367 +3413 IDDM14 HGNC:HGNC:5368 +3414 IDDM15 MIM:601666|HGNC:HGNC:5369 +3415 IDDM16 HGNC:HGNC:5370 +3416 IDE MIM:146680|HGNC:HGNC:5381|Ensembl:ENSG00000119912|Vega:OTTHUMG00000018759 +3417 IDH1 MIM:147700|HGNC:HGNC:5382|Ensembl:ENSG00000138413|Vega:OTTHUMG00000132943 +3418 IDH2 MIM:147650|HGNC:HGNC:5383|Ensembl:ENSG00000182054|Vega:OTTHUMG00000149815 +3419 IDH3A MIM:601149|HGNC:HGNC:5384|Ensembl:ENSG00000166411|Vega:OTTHUMG00000143732 +3420 IDH3B MIM:604526|HGNC:HGNC:5385|Ensembl:ENSG00000101365|Vega:OTTHUMG00000031699 +3421 IDH3G MIM:300089|HGNC:HGNC:5386|Ensembl:ENSG00000067829|Vega:OTTHUMG00000024219 +3422 IDI1 MIM:604055|HGNC:HGNC:5387|Ensembl:ENSG00000067064|Vega:OTTHUMG00000017536 +3423 IDS MIM:300823|HGNC:HGNC:5389|Ensembl:ENSG00000010404|Vega:OTTHUMG00000022615 +3424 IDSP1 HGNC:HGNC:5390 +3425 IDUA MIM:252800|HGNC:HGNC:5391|Ensembl:ENSG00000127415|Vega:OTTHUMG00000088901 +3426 CFI MIM:217030|HGNC:HGNC:5394|Ensembl:ENSG00000205403|Vega:OTTHUMG00000161109 +3428 IFI16 MIM:147586|HGNC:HGNC:5395|Ensembl:ENSG00000163565|Vega:OTTHUMG00000037108 +3429 IFI27 MIM:600009|HGNC:HGNC:5397|Ensembl:ENSG00000165949|Vega:OTTHUMG00000171303 +3430 IFI35 MIM:600735|HGNC:HGNC:5399|Ensembl:ENSG00000068079|Vega:OTTHUMG00000167720 +3431 SP110 MIM:604457|HGNC:HGNC:5401|Ensembl:ENSG00000135899|Vega:OTTHUMG00000133204 +3433 IFIT2 MIM:147040|HGNC:HGNC:5409|Ensembl:ENSG00000119922|Vega:OTTHUMG00000018707 +3434 IFIT1 MIM:147690|HGNC:HGNC:5407|Ensembl:ENSG00000185745|Vega:OTTHUMG00000018712 +3437 IFIT3 MIM:604650|HGNC:HGNC:5411|Ensembl:ENSG00000119917|Vega:OTTHUMG00000018708 +3438 IFN1@ - +3439 IFNA1 MIM:147660|HGNC:HGNC:5417|Ensembl:ENSG00000197919|Vega:OTTHUMG00000019673 +3440 IFNA2 MIM:147562|HGNC:HGNC:5423|Ensembl:ENSG00000188379|Vega:OTTHUMG00000019674 +3441 IFNA4 MIM:147564|HGNC:HGNC:5425|Ensembl:ENSG00000236637|Vega:OTTHUMG00000019660 +3442 IFNA5 MIM:147565|HGNC:HGNC:5426|Ensembl:ENSG00000147873|Vega:OTTHUMG00000019664 +3443 IFNA6 MIM:147566|HGNC:HGNC:5427|Ensembl:ENSG00000120235|Vega:OTTHUMG00000019676 +3444 IFNA7 MIM:147567|HGNC:HGNC:5428|Ensembl:ENSG00000214042|Vega:OTTHUMG00000019662 +3445 IFNA8 MIM:147568|HGNC:HGNC:5429|Ensembl:ENSG00000120242|Vega:OTTHUMG00000019677 +3446 IFNA10 MIM:147577|HGNC:HGNC:5418|Ensembl:ENSG00000186803|Vega:OTTHUMG00000019658 +3447 IFNA13 MIM:147578|HGNC:HGNC:5419|Ensembl:ENSG00000233816|Vega:OTTHUMG00000019675 +3448 IFNA14 MIM:147579|HGNC:HGNC:5420|Ensembl:ENSG00000228083|Vega:OTTHUMG00000019665 +3449 IFNA16 MIM:147580|HGNC:HGNC:5421|Ensembl:ENSG00000147885|Vega:OTTHUMG00000019663 +3451 IFNA17 MIM:147583|HGNC:HGNC:5422|Ensembl:ENSG00000234829|Vega:OTTHUMG00000019667 +3452 IFNA21 MIM:147584|HGNC:HGNC:5424|Ensembl:ENSG00000137080|Vega:OTTHUMG00000019653 +3453 IFNA22P HGNC:HGNC:5431 +3454 IFNAR1 MIM:107450|HGNC:HGNC:5432|Ensembl:ENSG00000142166|Vega:OTTHUMG00000065126 +3455 IFNAR2 MIM:602376|HGNC:HGNC:5433|Ensembl:ENSG00000159110|Vega:OTTHUMG00000065127 +3456 IFNB1 MIM:147640|HGNC:HGNC:5434|Ensembl:ENSG00000171855|Vega:OTTHUMG00000019652 +3458 IFNG MIM:147570|HGNC:HGNC:5438|Ensembl:ENSG00000111537|Vega:OTTHUMG00000169113 +3459 IFNGR1 MIM:107470|HGNC:HGNC:5439|Ensembl:ENSG00000027697|Vega:OTTHUMG00000015656 +3460 IFNGR2 MIM:147569|HGNC:HGNC:5440|Ensembl:ENSG00000159128|Vega:OTTHUMG00000065188 +3461 IFNA11P HGNC:HGNC:5442 +3463 IFNA20P HGNC:HGNC:5444 +3466 IFNR MIM:147573|HGNC:HGNC:5447 +3467 IFNW1 MIM:147553|HGNC:HGNC:5448|Ensembl:ENSG00000177047|Vega:OTTHUMG00000019656 +3474 IFNWP19 HGNC:HGNC:5451 +3475 IFRD1 MIM:603502|HGNC:HGNC:5456|Ensembl:ENSG00000006652|Vega:OTTHUMG00000155124 +3476 IGBP1 MIM:300139|HGNC:HGNC:5461|Ensembl:ENSG00000089289|Vega:OTTHUMG00000021767 +3478 IGES MIM:147061|HGNC:HGNC:5463 +3479 IGF1 MIM:147440|HGNC:HGNC:5464|Ensembl:ENSG00000017427|Vega:OTTHUMG00000149910 +3480 IGF1R MIM:147370|HGNC:HGNC:5465|Ensembl:ENSG00000140443|Vega:OTTHUMG00000149851 +3481 IGF2 MIM:147470|HGNC:HGNC:5466|Ensembl:ENSG00000167244|Vega:OTTHUMG00000009395 +3482 IGF2R MIM:147280|HGNC:HGNC:5467|Ensembl:ENSG00000197081|Vega:OTTHUMG00000015945 +3483 IGFALS MIM:601489|HGNC:HGNC:5468|Ensembl:ENSG00000099769|Vega:OTTHUMG00000128638 +3484 IGFBP1 MIM:146730|HGNC:HGNC:5469|Ensembl:ENSG00000146678|Vega:OTTHUMG00000152343 +3485 IGFBP2 MIM:146731|HGNC:HGNC:5471|Ensembl:ENSG00000115457|Vega:OTTHUMG00000155341 +3486 IGFBP3 MIM:146732|HGNC:HGNC:5472|Ensembl:ENSG00000146674|Vega:OTTHUMG00000023769 +3487 IGFBP4 MIM:146733|HGNC:HGNC:5473|Ensembl:ENSG00000141753|Vega:OTTHUMG00000133326 +3488 IGFBP5 MIM:146734|HGNC:HGNC:5474|Ensembl:ENSG00000115461|Vega:OTTHUMG00000133058 +3489 IGFBP6 MIM:146735|HGNC:HGNC:5475|Ensembl:ENSG00000167779|Vega:OTTHUMG00000169773 +3490 IGFBP7 MIM:602867|HGNC:HGNC:5476|Ensembl:ENSG00000163453|Vega:OTTHUMG00000128772 +3491 CYR61 MIM:602369|HGNC:HGNC:2654|Ensembl:ENSG00000142871|Vega:OTTHUMG00000010577 +3492 IGH MIM:146910|MIM:147010|MIM:147070|HGNC:HGNC:5477 +3493 IGHA1 MIM:146900|HGNC:HGNC:5478|IMGT/GENE-DB:IGHA1 +3494 IGHA2 MIM:147000|HGNC:HGNC:5479|IMGT/GENE-DB:IGHA2 +3495 IGHD MIM:147170|HGNC:HGNC:5480|IMGT/GENE-DB:IGHD +3496 IGHDOR15@ MIM:146990 +3497 IGHE MIM:147180|HGNC:HGNC:5522|IMGT/GENE-DB:IGHE +3498 IGHEP1 HGNC:HGNC:5523|IMGT/GENE-DB:IGHEP1 +3499 IGHEP2 HGNC:HGNC:5524|IMGT/GENE-DB:IGHEP2 +3500 IGHG1 MIM:147100|HGNC:HGNC:5525|IMGT/GENE-DB:IGHG1 +3501 IGHG2 MIM:147110|HGNC:HGNC:5526|IMGT/GENE-DB:IGHG2 +3502 IGHG3 MIM:147120|HGNC:HGNC:5527|IMGT/GENE-DB:IGHG3 +3503 IGHG4 MIM:147130|HGNC:HGNC:5528|IMGT/GENE-DB:IGHG4 +3505 IGHGP HGNC:HGNC:5529|IMGT/GENE-DB:IGHGP +3507 IGHM MIM:147020|HGNC:HGNC:5541|IMGT/GENE-DB:IGHM +3508 IGHMBP2 MIM:600502|HGNC:HGNC:5542|Ensembl:ENSG00000132740|Vega:OTTHUMG00000167894 +3512 JCHAIN MIM:147790|HGNC:HGNC:5713|Ensembl:ENSG00000132465|Vega:OTTHUMG00000129909 +3513 IGJP1 HGNC:HGNC:5714 +3514 IGKC MIM:147200|HGNC:HGNC:5716|IMGT/GENE-DB:IGKC +3515 IGKDEL MIM:146780|HGNC:HGNC:5717 +3516 RBPJ MIM:147183|HGNC:HGNC:5724|Ensembl:ENSG00000168214|Vega:OTTHUMG00000097793 +3517 RBPJP2 HGNC:HGNC:5726 +3519 IGKV@ MIM:146980 +3523 IGKV3OR2-268 HGNC:HGNC:5830|IMGT/GENE-DB:IGKV3/OR2-268 +3525 IGKV1OR1-1 HGNC:HGNC:5764|IMGT/GENE-DB:IGKV1/OR1-1 +3527 IGKV3OR22-2 HGNC:HGNC:5833|IMGT/GENE-DB:IGKV3/OR22-2 +3529 IGKV2OR22-3 HGNC:HGNC:5812|IMGT/GENE-DB:IGKV2/OR22-3 +3530 IGKV1OR22-1 HGNC:HGNC:5772|IMGT/GENE-DB:IGKV1/OR22-1 +3531 IGKV1OR2-1 HGNC:HGNC:5760|IMGT/GENE-DB:IGKV1/OR2-1 +3532 IGKV1OR-2 HGNC:HGNC:5761|IMGT/GENE-DB:IGKV1/OR-2 +3534 IGKV1OR-4 HGNC:HGNC:5763|IMGT/GENE-DB:IGKV1/OR-4 +3535 IGL HGNC:HGNC:5853 +3537 IGLC1 MIM:147220|HGNC:HGNC:5855|IMGT/GENE-DB:IGLC1 +3538 IGLC2 HGNC:HGNC:5856|IMGT/GENE-DB:IGLC2 +3539 IGLC3 HGNC:HGNC:5857|IMGT/GENE-DB:IGLC3 +3540 IGLC4 HGNC:HGNC:5858|IMGT/GENE-DB:IGLC4 +3541 IGLC5 HGNC:HGNC:5859|IMGT/GENE-DB:IGLC5 +3542 IGLC6 HGNC:HGNC:5860|IMGT/GENE-DB:IGLC6 +3543 IGLL1 MIM:146770|HGNC:HGNC:5870|Ensembl:ENSG00000128322|Vega:OTTHUMG00000150673 +3544 IGLL2P HGNC:HGNC:5871 +3546 IGLV@ MIM:147240 +3547 IGSF1 MIM:300137|HGNC:HGNC:5948|Ensembl:ENSG00000147255|Vega:OTTHUMG00000022406 +3548 IHG1 MIM:308500|HGNC:HGNC:5954 +3549 IHH MIM:600726|HGNC:HGNC:5956|Ensembl:ENSG00000163501|Vega:OTTHUMG00000154631 +3550 IK MIM:600549|HGNC:HGNC:5958|Ensembl:ENSG00000113141|Vega:OTTHUMG00000163374 +3551 IKBKB MIM:603258|HGNC:HGNC:5960|Ensembl:ENSG00000104365|Vega:OTTHUMG00000164092 +3552 IL1A MIM:147760|HGNC:HGNC:5991|Ensembl:ENSG00000115008|Vega:OTTHUMG00000131315 +3553 IL1B MIM:147720|HGNC:HGNC:5992|Ensembl:ENSG00000125538|Vega:OTTHUMG00000131344 +3554 IL1R1 MIM:147810|HGNC:HGNC:5993|Ensembl:ENSG00000115594|Vega:OTTHUMG00000130783 +3556 IL1RAP MIM:602626|HGNC:HGNC:5995|Ensembl:ENSG00000196083|Vega:OTTHUMG00000156211 +3557 IL1RN MIM:147679|HGNC:HGNC:6000|Ensembl:ENSG00000136689|Vega:OTTHUMG00000131341 +3558 IL2 MIM:147680|HGNC:HGNC:6001|Ensembl:ENSG00000109471|Vega:OTTHUMG00000133075 +3559 IL2RA MIM:147730|HGNC:HGNC:6008|Ensembl:ENSG00000134460|Vega:OTTHUMG00000017616 +3560 IL2RB MIM:146710|HGNC:HGNC:6009|Ensembl:ENSG00000100385|Vega:OTTHUMG00000150534 +3561 IL2RG MIM:308380|HGNC:HGNC:6010|Ensembl:ENSG00000147168|Vega:OTTHUMG00000021787 +3562 IL3 MIM:147740|HGNC:HGNC:6011|Ensembl:ENSG00000164399|Vega:OTTHUMG00000059640 +3563 IL3RA MIM:308385|MIM:430000|HGNC:HGNC:6012|Ensembl:ENSG00000185291|Vega:OTTHUMG00000021059 +3565 IL4 MIM:147780|HGNC:HGNC:6014|Ensembl:ENSG00000113520|Vega:OTTHUMG00000059724 +3566 IL4R MIM:147781|HGNC:HGNC:6015|Ensembl:ENSG00000077238|Vega:OTTHUMG00000097015 +3567 IL5 MIM:147850|HGNC:HGNC:6016|Ensembl:ENSG00000113525|Vega:OTTHUMG00000059496 +3568 IL5RA MIM:147851|HGNC:HGNC:6017|Ensembl:ENSG00000091181|Vega:OTTHUMG00000090245 +3569 IL6 MIM:147620|HGNC:HGNC:6018|Ensembl:ENSG00000136244|Vega:OTTHUMG00000023178 +3570 IL6R MIM:147880|HGNC:HGNC:6019|Ensembl:ENSG00000160712|Vega:OTTHUMG00000036073 +3572 IL6ST MIM:600694|HGNC:HGNC:6021|Ensembl:ENSG00000134352|Vega:OTTHUMG00000097043 +3573 IL6STP1 HGNC:HGNC:6022 +3574 IL7 MIM:146660|HGNC:HGNC:6023|Ensembl:ENSG00000104432|Vega:OTTHUMG00000164620 +3575 IL7R MIM:146661|HGNC:HGNC:6024|Ensembl:ENSG00000168685|Vega:OTTHUMG00000090791 +3576 CXCL8 MIM:146930|HGNC:HGNC:6025|Ensembl:ENSG00000169429|Vega:OTTHUMG00000151316 +3577 CXCR1 MIM:146929|HGNC:HGNC:6026|Ensembl:ENSG00000163464|Vega:OTTHUMG00000133108 +3578 IL9 MIM:146931|HGNC:HGNC:6029|Ensembl:ENSG00000145839|Vega:OTTHUMG00000129147 +3579 CXCR2 MIM:146928|HGNC:HGNC:6027|Ensembl:ENSG00000180871|Vega:OTTHUMG00000133107 +3580 CXCR2P1 HGNC:HGNC:6028 +3581 IL9R MIM:300007|HGNC:HGNC:6030|Ensembl:ENSG00000124334|Vega:OTTHUMG00000022720 +3586 IL10 MIM:124092|HGNC:HGNC:5962|Ensembl:ENSG00000136634|Vega:OTTHUMG00000036386 +3587 IL10RA MIM:146933|HGNC:HGNC:5964|Ensembl:ENSG00000110324|Vega:OTTHUMG00000166523 +3588 IL10RB MIM:123889|HGNC:HGNC:5965|Ensembl:ENSG00000243646|Vega:OTTHUMG00000065128 +3589 IL11 MIM:147681|HGNC:HGNC:5966|Ensembl:ENSG00000095752|Vega:OTTHUMG00000180789 +3590 IL11RA MIM:600939|HGNC:HGNC:5967|Ensembl:ENSG00000137070|Vega:OTTHUMG00000019837 +3592 IL12A MIM:161560|HGNC:HGNC:5969|Ensembl:ENSG00000168811|Vega:OTTHUMG00000158942 +3593 IL12B MIM:161561|HGNC:HGNC:5970|Ensembl:ENSG00000113302|Vega:OTTHUMG00000130307 +3594 IL12RB1 MIM:601604|HGNC:HGNC:5971|Ensembl:ENSG00000096996|Vega:OTTHUMG00000183417 +3595 IL12RB2 MIM:601642|HGNC:HGNC:5972|Ensembl:ENSG00000081985|Vega:OTTHUMG00000009094 +3596 IL13 MIM:147683|HGNC:HGNC:5973|Ensembl:ENSG00000169194|Vega:OTTHUMG00000059723 +3597 IL13RA1 MIM:300119|HGNC:HGNC:5974|Ensembl:ENSG00000131724|Vega:OTTHUMG00000022258 +3598 IL13RA2 MIM:300130|HGNC:HGNC:5975|Ensembl:ENSG00000123496|Vega:OTTHUMG00000022229 +3600 IL15 MIM:600554|HGNC:HGNC:5977|Ensembl:ENSG00000164136|Vega:OTTHUMG00000133418 +3601 IL15RA MIM:601070|HGNC:HGNC:5978|Ensembl:ENSG00000134470|Vega:OTTHUMG00000017612 +3603 IL16 MIM:603035|HGNC:HGNC:5980|Ensembl:ENSG00000172349|Vega:OTTHUMG00000144186 +3604 TNFRSF9 MIM:602250|HGNC:HGNC:11924|Ensembl:ENSG00000049249|Vega:OTTHUMG00000001223 +3605 IL17A MIM:603149|HGNC:HGNC:5981|Ensembl:ENSG00000112115|Vega:OTTHUMG00000014840 +3606 IL18 MIM:600953|HGNC:HGNC:5986|Ensembl:ENSG00000150782|Vega:OTTHUMG00000167006 +3607 FOXK2 MIM:147685|HGNC:HGNC:6036|Ensembl:ENSG00000141568|Vega:OTTHUMG00000140374 +3608 ILF2 MIM:603181|HGNC:HGNC:6037|Ensembl:ENSG00000143621|Vega:OTTHUMG00000037087 +3609 ILF3 MIM:603182|HGNC:HGNC:6038|Ensembl:ENSG00000129351|Vega:OTTHUMG00000180587 +3611 ILK MIM:602366|HGNC:HGNC:6040|Ensembl:ENSG00000166333|Vega:OTTHUMG00000133407 +3612 IMPA1 MIM:602064|HGNC:HGNC:6050|Ensembl:ENSG00000133731|Vega:OTTHUMG00000164682 +3613 IMPA2 MIM:605922|HGNC:HGNC:6051|Ensembl:ENSG00000141401|Vega:OTTHUMG00000131693 +3614 IMPDH1 MIM:146690|HGNC:HGNC:6052|Ensembl:ENSG00000106348|Vega:OTTHUMG00000157713 +3615 IMPDH2 MIM:146691|HGNC:HGNC:6053|Ensembl:ENSG00000178035|Vega:OTTHUMG00000156771 +3617 IMPG1 MIM:602870|HGNC:HGNC:6055|Ensembl:ENSG00000112706|Vega:OTTHUMG00000015063 +3619 INCENP MIM:604411|HGNC:HGNC:6058|Ensembl:ENSG00000149503|Vega:OTTHUMG00000167470 +3620 IDO1 MIM:147435|HGNC:HGNC:6059|Ensembl:ENSG00000131203|Vega:OTTHUMG00000164057 +3621 ING1 MIM:601566|HGNC:HGNC:6062|Ensembl:ENSG00000153487|Vega:OTTHUMG00000017346 +3622 ING2 MIM:604215|HGNC:HGNC:6063|Ensembl:ENSG00000168556|Vega:OTTHUMG00000150502 +3623 INHA MIM:147380|HGNC:HGNC:6065|Ensembl:ENSG00000123999|Vega:OTTHUMG00000059237 +3624 INHBA MIM:147290|HGNC:HGNC:6066|Ensembl:ENSG00000122641|Vega:OTTHUMG00000023574 +3625 INHBB MIM:147390|HGNC:HGNC:6067|Ensembl:ENSG00000163083|Vega:OTTHUMG00000131437 +3626 INHBC MIM:601233|HGNC:HGNC:6068|Ensembl:ENSG00000175189|Vega:OTTHUMG00000169994 +3627 CXCL10 MIM:147310|HGNC:HGNC:10637|Ensembl:ENSG00000169245|Vega:OTTHUMG00000160887 +3628 INPP1 MIM:147263|HGNC:HGNC:6071|Ensembl:ENSG00000151689|Vega:OTTHUMG00000132672 +3630 INS MIM:176730|HGNC:HGNC:6081|Ensembl:ENSG00000254647|Vega:OTTHUMG00000009558 +3631 INPP4A MIM:600916|HGNC:HGNC:6074|Ensembl:ENSG00000040933|Vega:OTTHUMG00000153106 +3632 INPP5A MIM:600106|HGNC:HGNC:6076|Ensembl:ENSG00000068383|Vega:OTTHUMG00000019293 +3633 INPP5B MIM:147264|HGNC:HGNC:6077|Ensembl:ENSG00000204084|Vega:OTTHUMG00000004436 +3635 INPP5D MIM:601582|HGNC:HGNC:6079|Ensembl:ENSG00000168918|Vega:OTTHUMG00000133688 +3636 INPPL1 MIM:600829|HGNC:HGNC:6080|Ensembl:ENSG00000165458|Vega:OTTHUMG00000167879 +3638 INSIG1 MIM:602055|HGNC:HGNC:6083|Ensembl:ENSG00000186480|Vega:OTTHUMG00000151330 +3640 INSL3 MIM:146738|HGNC:HGNC:6086|Ensembl:ENSG00000248099|Vega:OTTHUMG00000183481 +3641 INSL4 MIM:600910|HGNC:HGNC:6087|Ensembl:ENSG00000120211|Vega:OTTHUMG00000019494 +3642 INSM1 MIM:600010|HGNC:HGNC:6090|Ensembl:ENSG00000173404|Vega:OTTHUMG00000032004 +3643 INSR MIM:147670|HGNC:HGNC:6091|Ensembl:ENSG00000171105|Vega:OTTHUMG00000181992 +3645 INSRR MIM:147671|HGNC:HGNC:6093|Ensembl:ENSG00000027644|Vega:OTTHUMG00000041291 +3646 EIF3E MIM:602210|HGNC:HGNC:3277|Ensembl:ENSG00000104408|Vega:OTTHUMG00000164858 +3647 EIF3EP1 HGNC:HGNC:6102 +3651 PDX1 MIM:600733|HGNC:HGNC:6107|Ensembl:ENSG00000139515|Vega:OTTHUMG00000016638 +3652 IPP MIM:147485|HGNC:HGNC:6108|Ensembl:ENSG00000197429|Vega:OTTHUMG00000008004 +3653 IPW MIM:601491|HGNC:HGNC:6109 +3654 IRAK1 MIM:300283|HGNC:HGNC:6112|Ensembl:ENSG00000184216|Vega:OTTHUMG00000024228 +3655 ITGA6 MIM:147556|HGNC:HGNC:6142|Ensembl:ENSG00000091409|Vega:OTTHUMG00000132277 +3656 IRAK2 MIM:603304|HGNC:HGNC:6113|Ensembl:ENSG00000134070|Vega:OTTHUMG00000155358 +3658 IREB2 MIM:147582|HGNC:HGNC:6115|Ensembl:ENSG00000136381|Vega:OTTHUMG00000143861 +3659 IRF1 MIM:147575|HGNC:HGNC:6116|Ensembl:ENSG00000125347|Vega:OTTHUMG00000059497 +3660 IRF2 MIM:147576|HGNC:HGNC:6117|Ensembl:ENSG00000168310|Vega:OTTHUMG00000160606 +3661 IRF3 MIM:603734|HGNC:HGNC:6118|Ensembl:ENSG00000126456|Vega:OTTHUMG00000183287 +3662 IRF4 MIM:601900|HGNC:HGNC:6119|Ensembl:ENSG00000137265|Vega:OTTHUMG00000016294 +3663 IRF5 MIM:607218|HGNC:HGNC:6120|Ensembl:ENSG00000128604|Vega:OTTHUMG00000158410 +3664 IRF6 MIM:607199|HGNC:HGNC:6121|Ensembl:ENSG00000117595|Vega:OTTHUMG00000036521 +3665 IRF7 MIM:605047|HGNC:HGNC:6122|Ensembl:ENSG00000185507|Vega:OTTHUMG00000132019 +3667 IRS1 MIM:147545|HGNC:HGNC:6125|Ensembl:ENSG00000169047|Vega:OTTHUMG00000133179 +3669 ISG20 MIM:604533|HGNC:HGNC:6130|Ensembl:ENSG00000172183|Vega:OTTHUMG00000148679 +3670 ISL1 MIM:600366|HGNC:HGNC:6132|Ensembl:ENSG00000016082|Vega:OTTHUMG00000162281 +3671 ISLR MIM:602059|HGNC:HGNC:6133|Ensembl:ENSG00000129009|Vega:OTTHUMG00000137623 +3672 ITGA1 MIM:192968|HGNC:HGNC:6134|Ensembl:ENSG00000213949|Vega:OTTHUMG00000131163 +3673 ITGA2 MIM:192974|HGNC:HGNC:6137|Ensembl:ENSG00000164171|Vega:OTTHUMG00000131165 +3674 ITGA2B MIM:607759|HGNC:HGNC:6138|Ensembl:ENSG00000005961|Vega:OTTHUMG00000177935 +3675 ITGA3 MIM:605025|HGNC:HGNC:6139|Ensembl:ENSG00000005884|Vega:OTTHUMG00000161890 +3676 ITGA4 MIM:192975|HGNC:HGNC:6140|Ensembl:ENSG00000115232|Vega:OTTHUMG00000154212 +3678 ITGA5 MIM:135620|HGNC:HGNC:6141|Ensembl:ENSG00000161638|Vega:OTTHUMG00000169841 +3679 ITGA7 MIM:600536|HGNC:HGNC:6143|Ensembl:ENSG00000135424|Vega:OTTHUMG00000170699 +3680 ITGA9 MIM:603963|HGNC:HGNC:6145|Ensembl:ENSG00000144668|Vega:OTTHUMG00000130815 +3681 ITGAD MIM:602453|HGNC:HGNC:6146|Ensembl:ENSG00000156886|Vega:OTTHUMG00000176614 +3682 ITGAE MIM:604682|HGNC:HGNC:6147|Ensembl:ENSG00000083457|Vega:OTTHUMG00000177634 +3683 ITGAL MIM:153370|HGNC:HGNC:6148|Ensembl:ENSG00000005844|Vega:OTTHUMG00000176964 +3684 ITGAM MIM:120980|HGNC:HGNC:6149|Ensembl:ENSG00000169896|Vega:OTTHUMG00000176612 +3685 ITGAV MIM:193210|HGNC:HGNC:6150|Ensembl:ENSG00000138448|Vega:OTTHUMG00000132635 +3687 ITGAX MIM:151510|HGNC:HGNC:6152|Ensembl:ENSG00000140678|Vega:OTTHUMG00000132465 +3688 ITGB1 MIM:135630|HGNC:HGNC:6153|Ensembl:ENSG00000150093|Vega:OTTHUMG00000017928 +3689 ITGB2 MIM:600065|HGNC:HGNC:6155|Ensembl:ENSG00000160255|Vega:OTTHUMG00000090257 +3690 ITGB3 MIM:173470|HGNC:HGNC:6156|Ensembl:ENSG00000259207|Ensembl:ENSG00000259753|Vega:OTTHUMG00000171956|Vega:OTTHUMG00000171957 +3691 ITGB4 MIM:147557|HGNC:HGNC:6158|Ensembl:ENSG00000132470|Vega:OTTHUMG00000179814 +3692 EIF6 MIM:602912|HGNC:HGNC:6159|Ensembl:ENSG00000242372|Vega:OTTHUMG00000032328 +3693 ITGB5 MIM:147561|HGNC:HGNC:6160|Ensembl:ENSG00000082781|Vega:OTTHUMG00000159432 +3694 ITGB6 MIM:147558|HGNC:HGNC:6161|Ensembl:ENSG00000115221|Vega:OTTHUMG00000132026 +3695 ITGB7 MIM:147559|HGNC:HGNC:6162|Ensembl:ENSG00000139626|Vega:OTTHUMG00000169775 +3696 ITGB8 MIM:604160|HGNC:HGNC:6163|Ensembl:ENSG00000105855|Vega:OTTHUMG00000023594 +3697 ITIH1 MIM:147270|HGNC:HGNC:6166|Ensembl:ENSG00000055957|Vega:OTTHUMG00000150312 +3698 ITIH2 MIM:146640|HGNC:HGNC:6167|Ensembl:ENSG00000151655|Vega:OTTHUMG00000017633 +3699 ITIH3 MIM:146650|HGNC:HGNC:6168|Ensembl:ENSG00000162267|Vega:OTTHUMG00000158956 +3700 ITIH4 MIM:600564|HGNC:HGNC:6169|Ensembl:ENSG00000055955|Vega:OTTHUMG00000159023 +3702 ITK MIM:186973|HGNC:HGNC:6171|Ensembl:ENSG00000113263|Vega:OTTHUMG00000130245 +3703 STT3A MIM:601134|HGNC:HGNC:6172|Ensembl:ENSG00000134910|Vega:OTTHUMG00000165852 +3704 ITPA MIM:147520|HGNC:HGNC:6176|Ensembl:ENSG00000125877|Vega:OTTHUMG00000031738 +3705 ITPK1 MIM:601838|HGNC:HGNC:6177|Ensembl:ENSG00000100605|Vega:OTTHUMG00000171226 +3706 ITPKA MIM:147521|HGNC:HGNC:6178|Ensembl:ENSG00000137825|Vega:OTTHUMG00000130343 +3707 ITPKB MIM:147522|HGNC:HGNC:6179|Ensembl:ENSG00000143772|Vega:OTTHUMG00000037582 +3708 ITPR1 MIM:147265|HGNC:HGNC:6180|Ensembl:ENSG00000150995|Vega:OTTHUMG00000154996 +3709 ITPR2 MIM:600144|HGNC:HGNC:6181|Ensembl:ENSG00000123104|Vega:OTTHUMG00000169181 +3710 ITPR3 MIM:147267|HGNC:HGNC:6182|Ensembl:ENSG00000096433|Vega:OTTHUMG00000014532 +3712 IVD MIM:607036|HGNC:HGNC:6186|Ensembl:ENSG00000128928|Vega:OTTHUMG00000129984 +3713 IVL MIM:147360|HGNC:HGNC:6187|Ensembl:ENSG00000163207|Vega:OTTHUMG00000012451 +3714 JAG2 MIM:602570|HGNC:HGNC:6189|Ensembl:ENSG00000184916|Vega:OTTHUMG00000140172 +3716 JAK1 MIM:147795|HGNC:HGNC:6190|Ensembl:ENSG00000162434|Vega:OTTHUMG00000009310 +3717 JAK2 MIM:147796|HGNC:HGNC:6192|Ensembl:ENSG00000096968|Vega:OTTHUMG00000019490 +3718 JAK3 MIM:600173|HGNC:HGNC:6193|Ensembl:ENSG00000105639|Vega:OTTHUMG00000165648 +3719 JBS MIM:147791|HGNC:HGNC:6194 +3720 JARID2 MIM:601594|HGNC:HGNC:6196|Ensembl:ENSG00000008083|Vega:OTTHUMG00000014293 +3725 JUN MIM:165160|HGNC:HGNC:6204|Ensembl:ENSG00000177606|Vega:OTTHUMG00000008376 +3726 JUNB MIM:165161|HGNC:HGNC:6205|Ensembl:ENSG00000171223|Vega:OTTHUMG00000180373 +3727 JUND MIM:165162|HGNC:HGNC:6206|Ensembl:ENSG00000130522|Vega:OTTHUMG00000183355 +3728 JUP MIM:173325|HGNC:HGNC:6207|Ensembl:ENSG00000173801|Vega:OTTHUMG00000133494 +3730 ANOS1 MIM:300836|HGNC:HGNC:6211|Ensembl:ENSG00000011201|Vega:OTTHUMG00000021107 +3732 CD82 MIM:600623|HGNC:HGNC:6210|Ensembl:ENSG00000085117|Vega:OTTHUMG00000166472 +3734 ANOS2P HGNC:HGNC:6214 +3735 KARS MIM:601421|HGNC:HGNC:6215|Ensembl:ENSG00000065427|Vega:OTTHUMG00000137609 +3736 KCNA1 MIM:176260|HGNC:HGNC:6218|Ensembl:ENSG00000111262|Vega:OTTHUMG00000044398 +3737 KCNA2 MIM:176262|HGNC:HGNC:6220|Ensembl:ENSG00000177301|Vega:OTTHUMG00000011567 +3738 KCNA3 MIM:176263|HGNC:HGNC:6221|Ensembl:ENSG00000177272|Vega:OTTHUMG00000034493 +3739 KCNA4 MIM:176266|HGNC:HGNC:6222|Ensembl:ENSG00000182255|Vega:OTTHUMG00000166144 +3741 KCNA5 MIM:176267|HGNC:HGNC:6224|Ensembl:ENSG00000130037|Vega:OTTHUMG00000168232 +3742 KCNA6 MIM:176257|HGNC:HGNC:6225|Ensembl:ENSG00000130035|Ensembl:ENSG00000151079|Vega:OTTHUMG00000168225 +3743 KCNA7 MIM:176268|HGNC:HGNC:6226|Ensembl:ENSG00000104848|Vega:OTTHUMG00000183343 +3744 KCNA10 MIM:602420|HGNC:HGNC:6219|Ensembl:ENSG00000143105|Vega:OTTHUMG00000022785 +3745 KCNB1 MIM:600397|HGNC:HGNC:6231|Ensembl:ENSG00000158445|Vega:OTTHUMG00000033051 +3746 KCNC1 MIM:176258|HGNC:HGNC:6233|Ensembl:ENSG00000129159|Vega:OTTHUMG00000166359 +3747 KCNC2 MIM:176256|HGNC:HGNC:6234|Ensembl:ENSG00000166006|Vega:OTTHUMG00000169717 +3748 KCNC3 MIM:176264|HGNC:HGNC:6235|Ensembl:ENSG00000131398|Vega:OTTHUMG00000044580 +3749 KCNC4 MIM:176265|HGNC:HGNC:6236|Ensembl:ENSG00000116396|Vega:OTTHUMG00000011037 +3750 KCND1 MIM:300281|HGNC:HGNC:6237|Ensembl:ENSG00000102057|Vega:OTTHUMG00000024127 +3751 KCND2 MIM:605410|HGNC:HGNC:6238|Ensembl:ENSG00000184408|Vega:OTTHUMG00000156989 +3752 KCND3 MIM:605411|HGNC:HGNC:6239|Ensembl:ENSG00000171385|Vega:OTTHUMG00000011989 +3753 KCNE1 MIM:176261|HGNC:HGNC:6240|Ensembl:ENSG00000180509|Vega:OTTHUMG00000086236 +3754 KCNF1 MIM:603787|HGNC:HGNC:6246|Ensembl:ENSG00000162975|Vega:OTTHUMG00000119054 +3755 KCNG1 MIM:603788|HGNC:HGNC:6248|Ensembl:ENSG00000026559|Vega:OTTHUMG00000032745 +3756 KCNH1 MIM:603305|HGNC:HGNC:6250|Ensembl:ENSG00000143473|Vega:OTTHUMG00000036309 +3757 KCNH2 MIM:152427|HGNC:HGNC:6251|Ensembl:ENSG00000055118|Vega:OTTHUMG00000158341 +3758 KCNJ1 MIM:600359|HGNC:HGNC:6255|Ensembl:ENSG00000151704|Vega:OTTHUMG00000048247 +3759 KCNJ2 MIM:600681|HGNC:HGNC:6263|Ensembl:ENSG00000123700|Vega:OTTHUMG00000180351 +3760 KCNJ3 MIM:601534|HGNC:HGNC:6264|Ensembl:ENSG00000162989|Vega:OTTHUMG00000131937 +3761 KCNJ4 MIM:600504|HGNC:HGNC:6265|Ensembl:ENSG00000168135|Vega:OTTHUMG00000151131 +3762 KCNJ5 MIM:600734|HGNC:HGNC:6266|Ensembl:ENSG00000120457|Vega:OTTHUMG00000165795 +3763 KCNJ6 MIM:600877|HGNC:HGNC:6267|Ensembl:ENSG00000157542|Vega:OTTHUMG00000086667 +3764 KCNJ8 MIM:600935|HGNC:HGNC:6269|Ensembl:ENSG00000121361|Vega:OTTHUMG00000169093 +3765 KCNJ9 MIM:600932|HGNC:HGNC:6270|Ensembl:ENSG00000162728|Vega:OTTHUMG00000024072 +3766 KCNJ10 MIM:602208|HGNC:HGNC:6256|Ensembl:ENSG00000177807|Vega:OTTHUMG00000024073 +3767 KCNJ11 MIM:600937|HGNC:HGNC:6257|Ensembl:ENSG00000187486|Vega:OTTHUMG00000165914 +3768 KCNJ12 MIM:602323|HGNC:HGNC:6258|Ensembl:ENSG00000184185|Vega:OTTHUMG00000132039 +3769 KCNJ13 MIM:603208|HGNC:HGNC:6259|Ensembl:ENSG00000115474|Vega:OTTHUMG00000153292 +3770 KCNJ14 MIM:603953|HGNC:HGNC:6260|Ensembl:ENSG00000182324|Vega:OTTHUMG00000183307 +3772 KCNJ15 MIM:602106|HGNC:HGNC:6261|Ensembl:ENSG00000157551|Vega:OTTHUMG00000090609 +3773 KCNJ16 MIM:605722|HGNC:HGNC:6262|Ensembl:ENSG00000153822|Vega:OTTHUMG00000180349 +3775 KCNK1 MIM:601745|HGNC:HGNC:6272|Ensembl:ENSG00000135750|Vega:OTTHUMG00000037923 +3776 KCNK2 MIM:603219|HGNC:HGNC:6277|Ensembl:ENSG00000082482|Vega:OTTHUMG00000037017 +3777 KCNK3 MIM:603220|HGNC:HGNC:6278|Ensembl:ENSG00000171303|Vega:OTTHUMG00000125530 +3778 KCNMA1 MIM:600150|HGNC:HGNC:6284|Ensembl:ENSG00000156113|Vega:OTTHUMG00000018543 +3779 KCNMB1 MIM:603951|HGNC:HGNC:6285|Ensembl:ENSG00000145936|Vega:OTTHUMG00000130439 +3780 KCNN1 MIM:602982|HGNC:HGNC:6290|Ensembl:ENSG00000105642|Vega:OTTHUMG00000183482 +3781 KCNN2 MIM:605879|HGNC:HGNC:6291|Ensembl:ENSG00000080709|Vega:OTTHUMG00000128836 +3782 KCNN3 MIM:602983|HGNC:HGNC:6292|Ensembl:ENSG00000143603|Vega:OTTHUMG00000037260 +3783 KCNN4 MIM:602754|HGNC:HGNC:6293|Ensembl:ENSG00000104783|Vega:OTTHUMG00000182779 +3784 KCNQ1 MIM:607542|HGNC:HGNC:6294|Ensembl:ENSG00000053918|Vega:OTTHUMG00000009900 +3785 KCNQ2 MIM:602235|HGNC:HGNC:6296|Ensembl:ENSG00000075043|Vega:OTTHUMG00000033049 +3786 KCNQ3 MIM:602232|HGNC:HGNC:6297|Ensembl:ENSG00000184156|Vega:OTTHUMG00000137472 +3787 KCNS1 MIM:602905|HGNC:HGNC:6300|Ensembl:ENSG00000124134|Vega:OTTHUMG00000033079 +3788 KCNS2 MIM:602906|HGNC:HGNC:6301|Ensembl:ENSG00000156486|Vega:OTTHUMG00000044337 +3790 KCNS3 MIM:603888|HGNC:HGNC:6302|Ensembl:ENSG00000170745|Vega:OTTHUMG00000044150 +3791 KDR MIM:191306|HGNC:HGNC:6307|Ensembl:ENSG00000128052|Vega:OTTHUMG00000128734 +3792 KEL MIM:613883|HGNC:HGNC:6308|Ensembl:ENSG00000197993|Vega:OTTHUMG00000157159 +3795 KHK MIM:614058|HGNC:HGNC:6315|Ensembl:ENSG00000138030|Vega:OTTHUMG00000097077 +3796 KIF2A MIM:602591|HGNC:HGNC:6318|Ensembl:ENSG00000068796|Vega:OTTHUMG00000097755 +3797 KIF3C MIM:602845|HGNC:HGNC:6321|Ensembl:ENSG00000084731|Vega:OTTHUMG00000094797 +3798 KIF5A MIM:602821|HGNC:HGNC:6323|Ensembl:ENSG00000155980|Vega:OTTHUMG00000170143 +3799 KIF5B MIM:602809|HGNC:HGNC:6324|Ensembl:ENSG00000170759|Vega:OTTHUMG00000017913 +3800 KIF5C MIM:604593|HGNC:HGNC:6325|Ensembl:ENSG00000168280|Vega:OTTHUMG00000153779 +3801 KIFC3 MIM:604535|HGNC:HGNC:6326|Ensembl:ENSG00000140859|Vega:OTTHUMG00000133455 +3802 KIR2DL1 MIM:604936|HGNC:HGNC:6329|Ensembl:ENSG00000125498|Vega:OTTHUMG00000065885 +3803 KIR2DL2 MIM:604937|HGNC:HGNC:6330 +3804 KIR2DL3 MIM:604938|HGNC:HGNC:6331|Ensembl:ENSG00000243772|Vega:OTTHUMG00000065887 +3805 KIR2DL4 MIM:604945|HGNC:HGNC:6332|Ensembl:ENSG00000189013|Vega:OTTHUMG00000065880 +3806 KIR2DS1 MIM:604952|HGNC:HGNC:6333 +3808 KIR2DS3 MIM:604954|HGNC:HGNC:6335 +3809 KIR2DS4 MIM:604955|HGNC:HGNC:6336|Ensembl:ENSG00000221957|Vega:OTTHUMG00000065932 +3810 KIR2DS5 MIM:604956|HGNC:HGNC:6337 +3811 KIR3DL1 MIM:604946|HGNC:HGNC:6338|Ensembl:ENSG00000167633|Vega:OTTHUMG00000065933 +3812 KIR3DL2 MIM:604947|HGNC:HGNC:6339|Ensembl:ENSG00000240403|Vega:OTTHUMG00000065935 +3813 KIR3DS1 HGNC:HGNC:6340 +3814 KISS1 MIM:603286|HGNC:HGNC:6341|Ensembl:ENSG00000170498|Vega:OTTHUMG00000036060 +3815 KIT MIM:164920|HGNC:HGNC:6342|Ensembl:ENSG00000157404|Vega:OTTHUMG00000128713 +3816 KLK1 MIM:147910|HGNC:HGNC:6357|Ensembl:ENSG00000167748|Vega:OTTHUMG00000182876 +3817 KLK2 MIM:147960|HGNC:HGNC:6363|Ensembl:ENSG00000167751|Vega:OTTHUMG00000182963 +3818 KLKB1 MIM:229000|HGNC:HGNC:6371|Ensembl:ENSG00000164344|Vega:OTTHUMG00000150347 +3820 KLRB1 MIM:602890|HGNC:HGNC:6373|Ensembl:ENSG00000111796|Vega:OTTHUMG00000168581 +3821 KLRC1 MIM:161555|HGNC:HGNC:6374|Ensembl:ENSG00000134545|Vega:OTTHUMG00000168584 +3822 KLRC2 MIM:602891|HGNC:HGNC:6375|Ensembl:ENSG00000205809|Vega:OTTHUMG00000168532 +3823 KLRC3 MIM:602892|HGNC:HGNC:6376|Ensembl:ENSG00000205810|Vega:OTTHUMG00000167149 +3824 KLRD1 MIM:602894|HGNC:HGNC:6378|Ensembl:ENSG00000134539|Vega:OTTHUMG00000168419 +3827 KNG1 MIM:612358|HGNC:HGNC:6383|Ensembl:ENSG00000113889|Vega:OTTHUMG00000150348 +3831 KLC1 MIM:600025|HGNC:HGNC:6387|Ensembl:ENSG00000126214|Vega:OTTHUMG00000169227 +3832 KIF11 MIM:148760|HGNC:HGNC:6388|Ensembl:ENSG00000138160|Vega:OTTHUMG00000018761 +3833 KIFC1 MIM:603763|HGNC:HGNC:6389|Ensembl:ENSG00000237649|Vega:OTTHUMG00000031209 +3834 KIF25 MIM:603815|HGNC:HGNC:6390|Ensembl:ENSG00000125337|Vega:OTTHUMG00000016035 +3835 KIF22 MIM:603213|HGNC:HGNC:6391|Ensembl:ENSG00000079616|Vega:OTTHUMG00000097771 +3836 KPNA1 MIM:600686|HGNC:HGNC:6394|Ensembl:ENSG00000114030|Vega:OTTHUMG00000159487 +3837 KPNB1 MIM:602738|HGNC:HGNC:6400|Ensembl:ENSG00000108424|Vega:OTTHUMG00000036957 +3838 KPNA2 MIM:600685|HGNC:HGNC:6395|Ensembl:ENSG00000182481|Vega:OTTHUMG00000179784 +3839 KPNA3 MIM:601892|HGNC:HGNC:6396|Ensembl:ENSG00000102753|Vega:OTTHUMG00000016922 +3840 KPNA4 MIM:602970|HGNC:HGNC:6397|Ensembl:ENSG00000186432|Vega:OTTHUMG00000159033 +3841 KPNA5 MIM:604545|HGNC:HGNC:6398|Ensembl:ENSG00000196911|Vega:OTTHUMG00000015448 +3842 TNPO1 MIM:602901|HGNC:HGNC:6401|Ensembl:ENSG00000083312|Vega:OTTHUMG00000100967 +3843 IPO5 MIM:602008|HGNC:HGNC:6402|Ensembl:ENSG00000065150|Vega:OTTHUMG00000017244 +3844 KRASP1 HGNC:HGNC:6406 +3845 KRAS MIM:190070|HGNC:HGNC:6407|Ensembl:ENSG00000133703|Vega:OTTHUMG00000171193 +3846 KRTAP5-9 MIM:148021|HGNC:HGNC:23604|Ensembl:ENSG00000254997|Vega:OTTHUMG00000167263 +3848 KRT1 MIM:139350|HGNC:HGNC:6412|Ensembl:ENSG00000167768|Vega:OTTHUMG00000169749 +3849 KRT2 MIM:600194|HGNC:HGNC:6439|Ensembl:ENSG00000172867|Vega:OTTHUMG00000169748 +3850 KRT3 MIM:148043|HGNC:HGNC:6440|Ensembl:ENSG00000186442|Vega:OTTHUMG00000169799 +3851 KRT4 MIM:123940|HGNC:HGNC:6441|Ensembl:ENSG00000170477|Vega:OTTHUMG00000169800 +3852 KRT5 MIM:148040|HGNC:HGNC:6442|Ensembl:ENSG00000186081|Vega:OTTHUMG00000169657 +3853 KRT6A MIM:148041|HGNC:HGNC:6443|Ensembl:ENSG00000205420|Vega:OTTHUMG00000169597 +3854 KRT6B MIM:148042|HGNC:HGNC:6444|Ensembl:ENSG00000185479|Vega:OTTHUMG00000169593 +3855 KRT7 MIM:148059|HGNC:HGNC:6445|Ensembl:ENSG00000135480|Vega:OTTHUMG00000169580 +3856 KRT8 MIM:148060|HGNC:HGNC:6446|Ensembl:ENSG00000170421|Vega:OTTHUMG00000169881 +3857 KRT9 MIM:607606|HGNC:HGNC:6447|Ensembl:ENSG00000171403|Vega:OTTHUMG00000133599 +3858 KRT10 MIM:148080|HGNC:HGNC:6413|Ensembl:ENSG00000186395|Vega:OTTHUMG00000133368 +3859 KRT12 MIM:601687|HGNC:HGNC:6414|Ensembl:ENSG00000187242|Vega:OTTHUMG00000133369 +3860 KRT13 MIM:148065|HGNC:HGNC:6415|Ensembl:ENSG00000171401|Vega:OTTHUMG00000133434 +3861 KRT14 MIM:148066|HGNC:HGNC:6416|Ensembl:ENSG00000186847|Vega:OTTHUMG00000133426 +3866 KRT15 MIM:148030|HGNC:HGNC:6421|Ensembl:ENSG00000171346|Vega:OTTHUMG00000133435 +3868 KRT16 MIM:148067|HGNC:HGNC:6423|Ensembl:ENSG00000186832|Vega:OTTHUMG00000133495 +3872 KRT17 MIM:148069|HGNC:HGNC:6427|Ensembl:ENSG00000128422|Vega:OTTHUMG00000133505 +3875 KRT18 MIM:148070|HGNC:HGNC:6430|Ensembl:ENSG00000111057|Vega:OTTHUMG00000169882 +3876 KRT18P11 HGNC:HGNC:6431 +3879 KRT18P1 HGNC:HGNC:6434 +3880 KRT19 MIM:148020|HGNC:HGNC:6436|Ensembl:ENSG00000171345|Vega:OTTHUMG00000133422 +3881 KRT31 MIM:601077|HGNC:HGNC:6448|Ensembl:ENSG00000094796|Vega:OTTHUMG00000133423 +3882 KRT32 MIM:602760|HGNC:HGNC:6449|Ensembl:ENSG00000108759|Vega:OTTHUMG00000133430 +3883 KRT33A MIM:602761|HGNC:HGNC:6450|Ensembl:ENSG00000006059|Vega:OTTHUMG00000133432 +3884 KRT33B MIM:602762|HGNC:HGNC:6451|Ensembl:ENSG00000131738|Vega:OTTHUMG00000133429 +3885 KRT34 MIM:602763|HGNC:HGNC:6452|Ensembl:ENSG00000131737|Vega:OTTHUMG00000133436 +3886 KRT35 MIM:602764|HGNC:HGNC:6453|Ensembl:ENSG00000197079|Vega:OTTHUMG00000133425 +3887 KRT81 MIM:602153|HGNC:HGNC:6458|Ensembl:ENSG00000205426|Vega:OTTHUMG00000167574 +3888 KRT82 MIM:601078|HGNC:HGNC:6459|Ensembl:ENSG00000161850|Vega:OTTHUMG00000169636 +3889 KRT83 MIM:602765|HGNC:HGNC:6460|Ensembl:ENSG00000170523|Vega:OTTHUMG00000169632 +3890 KRT84 MIM:602766|HGNC:HGNC:6461|Ensembl:ENSG00000161849|Vega:OTTHUMG00000169634 +3891 KRT85 MIM:602767|HGNC:HGNC:6462|Ensembl:ENSG00000135443|Vega:OTTHUMG00000169633 +3892 KRT86 MIM:601928|HGNC:HGNC:6463|Ensembl:ENSG00000170442|Vega:OTTHUMG00000184153 +3895 KTN1 MIM:600381|HGNC:HGNC:6467|Ensembl:ENSG00000126777|Vega:OTTHUMG00000140312 +3896 KWE MIM:148370|HGNC:HGNC:6468 +3897 L1CAM MIM:308840|HGNC:HGNC:6470|Ensembl:ENSG00000198910|Vega:OTTHUMG00000024221 +3898 LAD1 MIM:602314|HGNC:HGNC:6472|Ensembl:ENSG00000159166|Vega:OTTHUMG00000035737 +3899 AFF3 MIM:601464|HGNC:HGNC:6473|Ensembl:ENSG00000144218|Vega:OTTHUMG00000153011 +3902 LAG3 MIM:153337|HGNC:HGNC:6476|Ensembl:ENSG00000089692|Vega:OTTHUMG00000169197 +3903 LAIR1 MIM:602992|HGNC:HGNC:6477|Ensembl:ENSG00000167613|Vega:OTTHUMG00000065545 +3904 LAIR2 MIM:602993|HGNC:HGNC:6478|Ensembl:ENSG00000167618|Vega:OTTHUMG00000065697 +3905 LAKLG MIM:153435|HGNC:HGNC:6479 +3906 LALBA MIM:149750|HGNC:HGNC:6480|Ensembl:ENSG00000167531|Vega:OTTHUMG00000170391 +3908 LAMA2 MIM:156225|HGNC:HGNC:6482|Ensembl:ENSG00000196569|Vega:OTTHUMG00000015545 +3909 LAMA3 MIM:600805|HGNC:HGNC:6483|Ensembl:ENSG00000053747|Vega:OTTHUMG00000131874 +3910 LAMA4 MIM:600133|HGNC:HGNC:6484|Ensembl:ENSG00000112769|Vega:OTTHUMG00000015386 +3911 LAMA5 MIM:601033|HGNC:HGNC:6485|Ensembl:ENSG00000130702|Vega:OTTHUMG00000032908 +3912 LAMB1 MIM:150240|HGNC:HGNC:6486|Ensembl:ENSG00000091136|Vega:OTTHUMG00000149966 +3913 LAMB2 MIM:150325|HGNC:HGNC:6487|Ensembl:ENSG00000172037|Vega:OTTHUMG00000156807 +3914 LAMB3 MIM:150310|HGNC:HGNC:6490|Ensembl:ENSG00000196878|Vega:OTTHUMG00000036360 +3915 LAMC1 MIM:150290|HGNC:HGNC:6492|Ensembl:ENSG00000135862|Vega:OTTHUMG00000035418 +3916 LAMP1 MIM:153330|HGNC:HGNC:6499|Ensembl:ENSG00000185896|Vega:OTTHUMG00000017380 +3918 LAMC2 MIM:150292|HGNC:HGNC:6493|Ensembl:ENSG00000058085|Vega:OTTHUMG00000035520 +3920 LAMP2 MIM:309060|HGNC:HGNC:6501|Ensembl:ENSG00000005893|Vega:OTTHUMG00000022301 +3921 RPSA MIM:150370|HGNC:HGNC:6502|Ensembl:ENSG00000168028|Vega:OTTHUMG00000131296 +3923 RPSAP13 HGNC:HGNC:6505 +3924 RPSAP14 HGNC:HGNC:6506 +3925 STMN1 MIM:151442|HGNC:HGNC:6510|Ensembl:ENSG00000117632|Vega:OTTHUMG00000007389 +3927 LASP1 MIM:602920|HGNC:HGNC:6513|Ensembl:ENSG00000002834|Vega:OTTHUMG00000133182 +3929 LBP MIM:151990|HGNC:HGNC:6517|Ensembl:ENSG00000129988|Vega:OTTHUMG00000032447 +3930 LBR MIM:600024|HGNC:HGNC:6518|Ensembl:ENSG00000143815|Vega:OTTHUMG00000037520 +3931 LCAT MIM:606967|HGNC:HGNC:6522|Ensembl:ENSG00000213398|Vega:OTTHUMG00000137551 +3932 LCK MIM:153390|HGNC:HGNC:6524|Ensembl:ENSG00000182866|Vega:OTTHUMG00000007463 +3933 LCN1 MIM:151675|HGNC:HGNC:6525|Ensembl:ENSG00000160349|Vega:OTTHUMG00000020908 +3934 LCN2 MIM:600181|HGNC:HGNC:6526|Ensembl:ENSG00000148346|Vega:OTTHUMG00000020734 +3936 LCP1 MIM:153430|HGNC:HGNC:6528|Ensembl:ENSG00000136167|Vega:OTTHUMG00000016864 +3937 LCP2 MIM:601603|HGNC:HGNC:6529|Ensembl:ENSG00000043462|Vega:OTTHUMG00000163121 +3938 LCT MIM:603202|HGNC:HGNC:6530|Ensembl:ENSG00000115850|Vega:OTTHUMG00000131738 +3939 LDHA MIM:150000|HGNC:HGNC:6535|Ensembl:ENSG00000134333|Vega:OTTHUMG00000167721 +3940 LDHAP1 HGNC:HGNC:6536 +3945 LDHB MIM:150100|HGNC:HGNC:6541|Ensembl:ENSG00000111716|Vega:OTTHUMG00000133760 +3947 LDHBP2 HGNC:HGNC:6543 +3948 LDHC MIM:150150|HGNC:HGNC:6544|Ensembl:ENSG00000166796|Vega:OTTHUMG00000167722 +3949 LDLR MIM:606945|HGNC:HGNC:6547|Ensembl:ENSG00000130164|Vega:OTTHUMG00000171935 +3950 LECT2 MIM:602882|HGNC:HGNC:6550|Ensembl:ENSG00000145826|Vega:OTTHUMG00000129146 +3952 LEP MIM:164160|HGNC:HGNC:6553|Ensembl:ENSG00000174697|Vega:OTTHUMG00000157564 +3953 LEPR MIM:601007|HGNC:HGNC:6554|Ensembl:ENSG00000116678|Vega:OTTHUMG00000009115 +3954 LETM1 MIM:604407|HGNC:HGNC:6556|Ensembl:ENSG00000168924|Vega:OTTHUMG00000121149 +3955 LFNG MIM:602576|HGNC:HGNC:6560|Ensembl:ENSG00000106003|Vega:OTTHUMG00000152043 +3956 LGALS1 MIM:150570|HGNC:HGNC:6561|Ensembl:ENSG00000100097|Vega:OTTHUMG00000150661 +3957 LGALS2 MIM:150571|HGNC:HGNC:6562|Ensembl:ENSG00000100079|Vega:OTTHUMG00000150590 +3958 LGALS3 MIM:153619|HGNC:HGNC:6563|Ensembl:ENSG00000131981|Vega:OTTHUMG00000171030 +3959 LGALS3BP MIM:600626|HGNC:HGNC:6564|Ensembl:ENSG00000108679|Vega:OTTHUMG00000177572 +3960 LGALS4 MIM:602518|HGNC:HGNC:6565|Ensembl:ENSG00000171747|Vega:OTTHUMG00000182608 +3963 LGALS7 MIM:600615|HGNC:HGNC:6568|Ensembl:ENSG00000205076|Vega:OTTHUMG00000182606 +3964 LGALS8 MIM:606099|HGNC:HGNC:6569|Ensembl:ENSG00000116977|Vega:OTTHUMG00000039953 +3965 LGALS9 MIM:601879|HGNC:HGNC:6570|Ensembl:ENSG00000168961|Vega:OTTHUMG00000179831 +3972 LHB MIM:152780|HGNC:HGNC:6584|Ensembl:ENSG00000104826|Vega:OTTHUMG00000183334 +3973 LHCGR MIM:152790|HGNC:HGNC:6585|Ensembl:ENSG00000138039|Vega:OTTHUMG00000129257 +3975 LHX1 MIM:601999|HGNC:HGNC:6593|Ensembl:ENSG00000273706|Vega:OTTHUMG00000188456 +3976 LIF MIM:159540|HGNC:HGNC:6596|Ensembl:ENSG00000128342|Vega:OTTHUMG00000150910 +3977 LIFR MIM:151443|HGNC:HGNC:6597|Ensembl:ENSG00000113594|Vega:OTTHUMG00000131138 +3978 LIG1 MIM:126391|HGNC:HGNC:6598|Ensembl:ENSG00000105486|Vega:OTTHUMG00000183187 +3980 LIG3 MIM:600940|HGNC:HGNC:6600|Ensembl:ENSG00000005156|Vega:OTTHUMG00000128519 +3981 LIG4 MIM:601837|HGNC:HGNC:6601|Ensembl:ENSG00000174405|Vega:OTTHUMG00000017328 +3982 LIM2 MIM:154045|HGNC:HGNC:6610|Ensembl:ENSG00000105370|Vega:OTTHUMG00000182896 +3983 ABLIM1 MIM:602330|HGNC:HGNC:78|Ensembl:ENSG00000099204|Vega:OTTHUMG00000019088 +3984 LIMK1 MIM:601329|HGNC:HGNC:6613|Ensembl:ENSG00000106683|Vega:OTTHUMG00000023448 +3985 LIMK2 MIM:601988|HGNC:HGNC:6614|Ensembl:ENSG00000182541|Vega:OTTHUMG00000151251 +3987 LIMS1 MIM:602567|HGNC:HGNC:6616|Ensembl:ENSG00000169756|Vega:OTTHUMG00000130983 +3988 LIPA MIM:613497|HGNC:HGNC:6617|Ensembl:ENSG00000107798|Vega:OTTHUMG00000018716 +3989 LIPB MIM:247980|HGNC:HGNC:6618 +3990 LIPC MIM:151670|HGNC:HGNC:6619|Ensembl:ENSG00000166035|Vega:OTTHUMG00000132632 +3991 LIPE MIM:151750|HGNC:HGNC:6621|Ensembl:ENSG00000079435|Vega:OTTHUMG00000182814 +3992 FADS1 MIM:606148|HGNC:HGNC:3574|Ensembl:ENSG00000149485|Vega:OTTHUMG00000157155 +3993 LLGL2 HGNC:HGNC:6629|Ensembl:ENSG00000073350|Vega:OTTHUMG00000179685 +3995 FADS3 MIM:606150|HGNC:HGNC:3576|Ensembl:ENSG00000221968|Vega:OTTHUMG00000167500 +3996 LLGL1 MIM:600966|HGNC:HGNC:6628|Ensembl:ENSG00000131899|Vega:OTTHUMG00000059396 +3998 LMAN1 MIM:601567|HGNC:HGNC:6631|Ensembl:ENSG00000074695|Vega:OTTHUMG00000132758 +4000 LMNA MIM:150330|HGNC:HGNC:6636|Ensembl:ENSG00000160789|Vega:OTTHUMG00000013961 +4001 LMNB1 MIM:150340|HGNC:HGNC:6637|Ensembl:ENSG00000113368|Vega:OTTHUMG00000128969 +4004 LMO1 MIM:186921|HGNC:HGNC:6641|Ensembl:ENSG00000166407|Vega:OTTHUMG00000165833 +4005 LMO2 MIM:180385|HGNC:HGNC:6642|Ensembl:ENSG00000135363|Vega:OTTHUMG00000157176 +4007 PRICKLE3 MIM:300111|HGNC:HGNC:6645|Ensembl:ENSG00000012211|Vega:OTTHUMG00000024134 +4008 LMO7 MIM:604362|HGNC:HGNC:6646|Ensembl:ENSG00000136153|Vega:OTTHUMG00000017093 +4009 LMX1A MIM:600298|HGNC:HGNC:6653|Ensembl:ENSG00000162761|Vega:OTTHUMG00000034575 +4010 LMX1B MIM:602575|HGNC:HGNC:6654|Ensembl:ENSG00000136944|Vega:OTTHUMG00000020692 +4012 LNPEP MIM:151300|HGNC:HGNC:6656|Ensembl:ENSG00000113441|Vega:OTTHUMG00000128719 +4013 VWA5A MIM:602929|HGNC:HGNC:6658|Ensembl:ENSG00000110002|Vega:OTTHUMG00000165971 +4014 LOR MIM:152445|HGNC:HGNC:6663|Ensembl:ENSG00000203782|Vega:OTTHUMG00000013938 +4015 LOX MIM:153455|HGNC:HGNC:6664|Ensembl:ENSG00000113083|Vega:OTTHUMG00000128914 +4016 LOXL1 MIM:153456|HGNC:HGNC:6665|Ensembl:ENSG00000129038|Vega:OTTHUMG00000137595 +4017 LOXL2 MIM:606663|HGNC:HGNC:6666|Ensembl:ENSG00000134013|Vega:OTTHUMG00000163797 +4018 LPA MIM:152200|HGNC:HGNC:6667|Ensembl:ENSG00000198670|Vega:OTTHUMG00000015956 +4019 LPAL1 HGNC:HGNC:6668 +4023 LPL MIM:609708|HGNC:HGNC:6677|Ensembl:ENSG00000175445|Vega:OTTHUMG00000036645 +4025 LPO MIM:150205|HGNC:HGNC:6678|Ensembl:ENSG00000167419|Vega:OTTHUMG00000178921 +4026 LPP MIM:600700|HGNC:HGNC:6679|Ensembl:ENSG00000145012|Vega:OTTHUMG00000156387 +4029 L1RE1 MIM:151626|HGNC:HGNC:6686 +4030 L1RE2 MIM:151628|HGNC:HGNC:6687 +4033 LRMP MIM:602003|HGNC:HGNC:6690|Ensembl:ENSG00000118308|Vega:OTTHUMG00000170192 +4034 LRCH4 HGNC:HGNC:6691|Ensembl:ENSG00000077454|Vega:OTTHUMG00000159544 +4035 LRP1 MIM:107770|HGNC:HGNC:6692|Ensembl:ENSG00000123384|Vega:OTTHUMG00000044412 +4036 LRP2 MIM:600073|HGNC:HGNC:6694|Ensembl:ENSG00000081479|Vega:OTTHUMG00000132179 +4037 LRP3 MIM:603159|HGNC:HGNC:6695|Ensembl:ENSG00000130881|Vega:OTTHUMG00000180343 +4038 LRP4 MIM:604270|HGNC:HGNC:6696|Ensembl:ENSG00000134569|Vega:OTTHUMG00000166700 +4040 LRP6 MIM:603507|HGNC:HGNC:6698|Ensembl:ENSG00000070018 +4041 LRP5 MIM:603506|HGNC:HGNC:6697|Ensembl:ENSG00000162337|Vega:OTTHUMG00000167570 +4043 LRPAP1 MIM:104225|HGNC:HGNC:6701|Ensembl:ENSG00000163956|Vega:OTTHUMG00000090299 +4045 LSAMP MIM:603241|HGNC:HGNC:6705|Ensembl:ENSG00000185565|Vega:OTTHUMG00000159308 +4046 LSP1 MIM:153432|HGNC:HGNC:6707|Ensembl:ENSG00000130592|Vega:OTTHUMG00000012252 +4047 LSS MIM:600909|HGNC:HGNC:6708|Ensembl:ENSG00000160285|Vega:OTTHUMG00000090633 +4048 LTA4H MIM:151570|HGNC:HGNC:6710|Ensembl:ENSG00000111144|Vega:OTTHUMG00000170355 +4049 LTA MIM:153440|HGNC:HGNC:6709|Ensembl:ENSG00000226979|Vega:OTTHUMG00000031135 +4050 LTB MIM:600978|HGNC:HGNC:6711|Ensembl:ENSG00000227507|Vega:OTTHUMG00000031136 +4051 CYP4F3 MIM:601270|HGNC:HGNC:2646|Ensembl:ENSG00000186529|Vega:OTTHUMG00000182374 +4052 LTBP1 MIM:150390|HGNC:HGNC:6714|Ensembl:ENSG00000049323|Vega:OTTHUMG00000152118 +4053 LTBP2 MIM:602091|HGNC:HGNC:6715|Ensembl:ENSG00000119681|Vega:OTTHUMG00000171476 +4054 LTBP3 MIM:602090|HGNC:HGNC:6716|Ensembl:ENSG00000168056|Vega:OTTHUMG00000166575 +4055 LTBR MIM:600979|HGNC:HGNC:6718|Ensembl:ENSG00000111321|Vega:OTTHUMG00000168356 +4056 LTC4S MIM:246530|HGNC:HGNC:6719|Ensembl:ENSG00000213316|Vega:OTTHUMG00000150314 +4057 LTF MIM:150210|HGNC:HGNC:6720|Ensembl:ENSG00000012223|Vega:OTTHUMG00000156325 +4058 LTK MIM:151520|HGNC:HGNC:6721|Ensembl:ENSG00000062524|Vega:OTTHUMG00000130339 +4059 BCAM MIM:612773|HGNC:HGNC:6722|Ensembl:ENSG00000187244|Vega:OTTHUMG00000180838 +4060 LUM MIM:600616|HGNC:HGNC:6724|Ensembl:ENSG00000139329|Vega:OTTHUMG00000170074 +4061 LY6E MIM:601384|HGNC:HGNC:6727|Ensembl:ENSG00000160932|Vega:OTTHUMG00000164754 +4062 LY6H MIM:603625|HGNC:HGNC:6728|Ensembl:ENSG00000176956|Vega:OTTHUMG00000154890 +4063 LY9 MIM:600684|HGNC:HGNC:6730|Ensembl:ENSG00000122224|Vega:OTTHUMG00000024007 +4064 CD180 MIM:602226|HGNC:HGNC:6726|Ensembl:ENSG00000134061|Vega:OTTHUMG00000131229 +4065 LY75 MIM:604524|HGNC:HGNC:6729|Ensembl:ENSG00000054219|Vega:OTTHUMG00000132025 +4066 LYL1 MIM:151440|HGNC:HGNC:6734|Ensembl:ENSG00000104903|Vega:OTTHUMG00000180736 +4067 LYN MIM:165120|HGNC:HGNC:6735|Ensembl:ENSG00000254087|Vega:OTTHUMG00000044345 +4068 SH2D1A MIM:300490|HGNC:HGNC:10820|Ensembl:ENSG00000183918|Vega:OTTHUMG00000022344 +4069 LYZ MIM:153450|HGNC:HGNC:6740|Ensembl:ENSG00000090382|Vega:OTTHUMG00000169342 +4070 TACSTD2 MIM:137290|HGNC:HGNC:11530|Ensembl:ENSG00000184292|Vega:OTTHUMG00000010067 +4071 TM4SF1 MIM:191155|HGNC:HGNC:11853|Ensembl:ENSG00000169908|Vega:OTTHUMG00000159597 +4072 EPCAM MIM:185535|HGNC:HGNC:11529|Ensembl:ENSG00000119888|Vega:OTTHUMG00000128853 +4074 M6PR MIM:154540|HGNC:HGNC:6752|Ensembl:ENSG00000003056|Vega:OTTHUMG00000168276 +4076 CAPRIN1 MIM:601178|HGNC:HGNC:6743|Ensembl:ENSG00000135387|Vega:OTTHUMG00000166248 +4077 NBR1 MIM:166945|HGNC:HGNC:6746|Ensembl:ENSG00000188554|Vega:OTTHUMG00000180878 +4080 MAA MIM:309800|HGNC:HGNC:6755 +4081 MAB21L1 MIM:601280|HGNC:HGNC:6757|Ensembl:ENSG00000180660|Vega:OTTHUMG00000016723 +4082 MARCKS MIM:177061|HGNC:HGNC:6759|Ensembl:ENSG00000277443|Vega:OTTHUMG00000188327 +4083 MARCKSP1 HGNC:HGNC:6760 +4084 MXD1 MIM:600021|HGNC:HGNC:6761|Ensembl:ENSG00000059728|Vega:OTTHUMG00000129646 +4085 MAD2L1 MIM:601467|HGNC:HGNC:6763|Ensembl:ENSG00000164109|Vega:OTTHUMG00000132967 +4086 SMAD1 MIM:601595|HGNC:HGNC:6767|Ensembl:ENSG00000170365|Vega:OTTHUMG00000161592 +4087 SMAD2 MIM:601366|HGNC:HGNC:6768|Ensembl:ENSG00000175387|Vega:OTTHUMG00000132652 +4088 SMAD3 MIM:603109|HGNC:HGNC:6769|Ensembl:ENSG00000166949|Vega:OTTHUMG00000133230 +4089 SMAD4 MIM:600993|HGNC:HGNC:6770|Ensembl:ENSG00000141646|Vega:OTTHUMG00000132696 +4090 SMAD5 MIM:603110|HGNC:HGNC:6771|Ensembl:ENSG00000113658|Vega:OTTHUMG00000163212 +4091 SMAD6 MIM:602931|HGNC:HGNC:6772|Ensembl:ENSG00000137834|Vega:OTTHUMG00000133218 +4092 SMAD7 MIM:602932|HGNC:HGNC:6773|Ensembl:ENSG00000101665|Vega:OTTHUMG00000132655 +4093 SMAD9 MIM:603295|HGNC:HGNC:6774|Ensembl:ENSG00000120693|Vega:OTTHUMG00000016740 +4094 MAF MIM:177075|HGNC:HGNC:6776|Ensembl:ENSG00000178573|Vega:OTTHUMG00000137621 +4095 MAFD1 MIM:125480|HGNC:HGNC:6777 +4096 MAFD2 MIM:309200|HGNC:HGNC:6778 +4097 MAFG MIM:602020|HGNC:HGNC:6781|Ensembl:ENSG00000197063|Vega:OTTHUMG00000177958 +4099 MAG MIM:159460|HGNC:HGNC:6783|Ensembl:ENSG00000105695|Vega:OTTHUMG00000183296 +4100 MAGEA1 MIM:300016|HGNC:HGNC:6796|Ensembl:ENSG00000198681|Vega:OTTHUMG00000024192 +4101 MAGEA2 MIM:300173|HGNC:HGNC:6800|Ensembl:ENSG00000268606|Vega:OTTHUMG00000188622 +4102 MAGEA3 MIM:300174|HGNC:HGNC:6801|Ensembl:ENSG00000221867|Vega:OTTHUMG00000022640 +4103 MAGEA4 MIM:300175|HGNC:HGNC:6802|Ensembl:ENSG00000147381|Vega:OTTHUMG00000024174 +4104 MAGEA5 MIM:300340|HGNC:HGNC:6803 +4105 MAGEA6 MIM:300176|HGNC:HGNC:6804|Ensembl:ENSG00000197172|Vega:OTTHUMG00000022642 +4106 MAGEA7P HGNC:HGNC:6805 +4107 MAGEA8 MIM:300341|HGNC:HGNC:6806|Ensembl:ENSG00000156009|Vega:OTTHUMG00000022635 +4108 MAGEA9 MIM:300342|HGNC:HGNC:6807|Ensembl:ENSG00000123584|Vega:OTTHUMG00000022621 +4109 MAGEA10 MIM:300343|HGNC:HGNC:6797|Ensembl:ENSG00000124260|Vega:OTTHUMG00000024180 +4110 MAGEA11 MIM:300344|HGNC:HGNC:6798|Ensembl:ENSG00000185247|Vega:OTTHUMG00000022633 +4111 MAGEA12 MIM:300177|HGNC:HGNC:6799|Ensembl:ENSG00000213401|Vega:OTTHUMG00000022650 +4112 MAGEB1 MIM:300097|HGNC:HGNC:6808|Ensembl:ENSG00000214107|Vega:OTTHUMG00000021322 +4113 MAGEB2 MIM:300098|HGNC:HGNC:6809|Ensembl:ENSG00000099399|Vega:OTTHUMG00000021319 +4114 MAGEB3 MIM:300152|HGNC:HGNC:6810|Ensembl:ENSG00000198798|Vega:OTTHUMG00000021320 +4115 MAGEB4 MIM:300153|HGNC:HGNC:6811|Ensembl:ENSG00000120289|Vega:OTTHUMG00000021321 +4116 MAGOH MIM:602603|HGNC:HGNC:6815|Ensembl:ENSG00000162385|Vega:OTTHUMG00000008932 +4117 MAK MIM:154235|HGNC:HGNC:6816|Ensembl:ENSG00000111837|Vega:OTTHUMG00000014247 +4118 MAL MIM:188860|HGNC:HGNC:6817|Ensembl:ENSG00000172005|Vega:OTTHUMG00000132011 +4121 MAN1A1 MIM:604344|HGNC:HGNC:6821|Ensembl:ENSG00000111885|Vega:OTTHUMG00000015472 +4122 MAN2A2 MIM:600988|HGNC:HGNC:6825|Ensembl:ENSG00000196547|Vega:OTTHUMG00000172385 +4123 MAN2C1 MIM:154580|HGNC:HGNC:6827|Ensembl:ENSG00000140400|Vega:OTTHUMG00000172698 +4124 MAN2A1 MIM:154582|HGNC:HGNC:6824|Ensembl:ENSG00000112893|Vega:OTTHUMG00000162834 +4125 MAN2B1 MIM:609458|HGNC:HGNC:6826|Ensembl:ENSG00000104774|Vega:OTTHUMG00000156397 +4126 MANBA MIM:609489|HGNC:HGNC:6831|Ensembl:ENSG00000109323|Vega:OTTHUMG00000131123 +4128 MAOA MIM:309850|HGNC:HGNC:6833|Ensembl:ENSG00000189221|Vega:OTTHUMG00000021387 +4129 MAOB MIM:309860|HGNC:HGNC:6834|Ensembl:ENSG00000069535|Vega:OTTHUMG00000021388 +4130 MAP1A MIM:600178|HGNC:HGNC:6835|Ensembl:ENSG00000166963|Vega:OTTHUMG00000059756 +4131 MAP1B MIM:157129|HGNC:HGNC:6836|Ensembl:ENSG00000131711|Vega:OTTHUMG00000100952 +4133 MAP2 MIM:157130|HGNC:HGNC:6839|Ensembl:ENSG00000078018|Vega:OTTHUMG00000132962 +4134 MAP4 MIM:157132|HGNC:HGNC:6862|Ensembl:ENSG00000047849|Vega:OTTHUMG00000156828 +4135 MAP6 MIM:601783|HGNC:HGNC:6868|Ensembl:ENSG00000171533|Vega:OTTHUMG00000165343 +4137 MAPT MIM:157140|HGNC:HGNC:6893|Ensembl:ENSG00000186868|Vega:OTTHUMG00000168833 +4139 MARK1 MIM:606511|HGNC:HGNC:6896|Ensembl:ENSG00000116141|Vega:OTTHUMG00000037351 +4140 MARK3 MIM:602678|HGNC:HGNC:6897|Ensembl:ENSG00000075413|Vega:OTTHUMG00000171789 +4141 MARS MIM:156560|HGNC:HGNC:6898|Ensembl:ENSG00000166986|Vega:OTTHUMG00000169996 +4142 MAS1 MIM:165180|HGNC:HGNC:6899|Ensembl:ENSG00000130368|Vega:OTTHUMG00000015944 +4143 MAT1A MIM:610550|HGNC:HGNC:6903|Ensembl:ENSG00000151224|Vega:OTTHUMG00000018613 +4144 MAT2A MIM:601468|HGNC:HGNC:6904|Ensembl:ENSG00000168906|Vega:OTTHUMG00000130174 +4145 MATK MIM:600038|HGNC:HGNC:6906|Ensembl:ENSG00000007264|Vega:OTTHUMG00000180916 +4146 MATN1 MIM:115437|HGNC:HGNC:6907|Ensembl:ENSG00000162510|Vega:OTTHUMG00000003705 +4147 MATN2 MIM:602108|HGNC:HGNC:6908|Ensembl:ENSG00000132561|Vega:OTTHUMG00000164795 +4148 MATN3 MIM:602109|HGNC:HGNC:6909|Ensembl:ENSG00000132031|Vega:OTTHUMG00000151788 +4149 MAX MIM:154950|HGNC:HGNC:6913|Ensembl:ENSG00000125952|Vega:OTTHUMG00000142809 +4150 MAZ MIM:600999|HGNC:HGNC:6914|Ensembl:ENSG00000103495|Vega:OTTHUMG00000190393 +4151 MB MIM:160000|HGNC:HGNC:6915|Ensembl:ENSG00000198125|Vega:OTTHUMG00000150606 +4152 MBD1 MIM:156535|HGNC:HGNC:6916|Ensembl:ENSG00000141644|Vega:OTTHUMG00000132669 +4153 MBL2 MIM:154545|HGNC:HGNC:6922|Ensembl:ENSG00000165471|Vega:OTTHUMG00000150270 +4154 MBNL1 MIM:606516|HGNC:HGNC:6923|Ensembl:ENSG00000152601|Vega:OTTHUMG00000159163 +4155 MBP MIM:159430|HGNC:HGNC:6925|Ensembl:ENSG00000197971|Vega:OTTHUMG00000132874 +4156 MBS1 MIM:157900|HGNC:HGNC:6926 +4157 MC1R MIM:155555|HGNC:HGNC:6929|Ensembl:ENSG00000258839|Vega:OTTHUMG00000171163 +4158 MC2R MIM:607397|HGNC:HGNC:6930|Ensembl:ENSG00000185231|Vega:OTTHUMG00000131721 +4159 MC3R MIM:155540|HGNC:HGNC:6931|Ensembl:ENSG00000124089|Vega:OTTHUMG00000032785 +4160 MC4R MIM:155541|HGNC:HGNC:6932|Ensembl:ENSG00000166603|Vega:OTTHUMG00000132766 +4161 MC5R MIM:600042|HGNC:HGNC:6933|Ensembl:ENSG00000176136|Vega:OTTHUMG00000131720 +4162 MCAM MIM:155735|HGNC:HGNC:6934|Ensembl:ENSG00000076706|Vega:OTTHUMG00000166197 +4163 MCC MIM:159350|HGNC:HGNC:6935|Ensembl:ENSG00000171444|Vega:OTTHUMG00000128804 +4166 CHST6 MIM:605294|HGNC:HGNC:6938|Ensembl:ENSG00000183196|Vega:OTTHUMG00000137612 +4167 MCDR1 MIM:136550|HGNC:HGNC:6939 +4168 MCF2 MIM:311030|HGNC:HGNC:6940|Ensembl:ENSG00000101977|Vega:OTTHUMG00000022537 +4170 MCL1 MIM:159552|HGNC:HGNC:6943|Ensembl:ENSG00000143384|Vega:OTTHUMG00000034867 +4171 MCM2 MIM:116945|HGNC:HGNC:6944|Ensembl:ENSG00000073111|Vega:OTTHUMG00000159637 +4172 MCM3 MIM:602693|HGNC:HGNC:6945|Ensembl:ENSG00000112118|Vega:OTTHUMG00000014844 +4173 MCM4 MIM:602638|HGNC:HGNC:6947|Ensembl:ENSG00000104738|Vega:OTTHUMG00000164205 +4174 MCM5 MIM:602696|HGNC:HGNC:6948|Ensembl:ENSG00000100297|Vega:OTTHUMG00000150961 +4175 MCM6 MIM:601806|HGNC:HGNC:6949|Ensembl:ENSG00000076003|Vega:OTTHUMG00000131739 +4176 MCM7 MIM:600592|HGNC:HGNC:6950|Ensembl:ENSG00000166508|Vega:OTTHUMG00000154671 +4179 CD46 MIM:120920|HGNC:HGNC:6953|Ensembl:ENSG00000117335|Vega:OTTHUMG00000036397 +4182 CD46P1 HGNC:HGNC:6959 +4183 MCS MIM:309605|HGNC:HGNC:6961 +4184 SMCP MIM:601148|HGNC:HGNC:6962|Ensembl:ENSG00000163206|Vega:OTTHUMG00000012452 +4185 ADAM11 MIM:155120|HGNC:HGNC:189|Ensembl:ENSG00000073670|Vega:OTTHUMG00000179038 +4188 MDFI MIM:604971|HGNC:HGNC:6967|Ensembl:ENSG00000112559|Vega:OTTHUMG00000014681 +4189 DNAJB9 MIM:602634|HGNC:HGNC:6968|Ensembl:ENSG00000128590|Vega:OTTHUMG00000154866 +4190 MDH1 MIM:154200|HGNC:HGNC:6970|Ensembl:ENSG00000014641|Vega:OTTHUMG00000129512 +4191 MDH2 MIM:154100|HGNC:HGNC:6971|Ensembl:ENSG00000146701|Vega:OTTHUMG00000023827 +4192 MDK MIM:162096|HGNC:HGNC:6972|Ensembl:ENSG00000110492|Vega:OTTHUMG00000150315 +4193 MDM2 MIM:164785|HGNC:HGNC:6973|Ensembl:ENSG00000135679|Vega:OTTHUMG00000142827 +4194 MDM4 MIM:602704|HGNC:HGNC:6974|Ensembl:ENSG00000198625|Vega:OTTHUMG00000035877 +4195 MDRV MIM:601846|HGNC:HGNC:6978 +4199 ME1 MIM:154250|HGNC:HGNC:6983|Ensembl:ENSG00000065833|Vega:OTTHUMG00000015111 +4200 ME2 MIM:154270|HGNC:HGNC:6984|Ensembl:ENSG00000082212|Vega:OTTHUMG00000132694 +4201 MEA1 MIM:143170|HGNC:HGNC:6986|Ensembl:ENSG00000124733|Vega:OTTHUMG00000014717 +4204 MECP2 MIM:300005|HGNC:HGNC:6990|Ensembl:ENSG00000169057|Vega:OTTHUMG00000024229 +4205 MEF2A MIM:600660|HGNC:HGNC:6993|Ensembl:ENSG00000068305|Vega:OTTHUMG00000171937 +4206 MEF2AP1 HGNC:HGNC:6994 +4207 BORCS8-MEF2B HGNC:HGNC:39979|Ensembl:ENSG00000064489|Vega:OTTHUMG00000154572 +4208 MEF2C MIM:600662|HGNC:HGNC:6996|Ensembl:ENSG00000081189|Vega:OTTHUMG00000162634 +4209 MEF2D MIM:600663|HGNC:HGNC:6997|Ensembl:ENSG00000116604|Vega:OTTHUMG00000033095 +4210 MEFV MIM:608107|HGNC:HGNC:6998|Ensembl:ENSG00000103313|Vega:OTTHUMG00000129324 +4211 MEIS1 MIM:601739|HGNC:HGNC:7000|Ensembl:ENSG00000143995|Vega:OTTHUMG00000150714 +4212 MEIS2 MIM:601740|HGNC:HGNC:7001|Ensembl:ENSG00000134138|Vega:OTTHUMG00000129781 +4213 MEIS3P1 HGNC:HGNC:7002 +4214 MAP3K1 MIM:600982|HGNC:HGNC:6848|Ensembl:ENSG00000095015|Vega:OTTHUMG00000059486 +4215 MAP3K3 MIM:602539|HGNC:HGNC:6855|Ensembl:ENSG00000198909|Vega:OTTHUMG00000178905 +4216 MAP3K4 MIM:602425|HGNC:HGNC:6856|Ensembl:ENSG00000085511|Vega:OTTHUMG00000015968 +4217 MAP3K5 MIM:602448|HGNC:HGNC:6857|Ensembl:ENSG00000197442|Vega:OTTHUMG00000015647 +4218 RAB8A MIM:165040|HGNC:HGNC:7007|Ensembl:ENSG00000167461|Vega:OTTHUMG00000182238 +4221 MEN1 MIM:613733|HGNC:HGNC:7010|Ensembl:ENSG00000133895|Vega:OTTHUMG00000045366 +4222 MEOX1 MIM:600147|HGNC:HGNC:7013|Ensembl:ENSG00000005102|Vega:OTTHUMG00000170513 +4223 MEOX2 MIM:600535|HGNC:HGNC:7014|Ensembl:ENSG00000106511|Vega:OTTHUMG00000152390 +4224 MEP1A MIM:600388|HGNC:HGNC:7015|Ensembl:ENSG00000112818|Vega:OTTHUMG00000014790 +4225 MEP1B MIM:600389|HGNC:HGNC:7020|Ensembl:ENSG00000141434|Vega:OTTHUMG00000179708 +4228 MER5 HGNC:HGNC:7023 +4232 MEST MIM:601029|HGNC:HGNC:7028|Ensembl:ENSG00000106484|Vega:OTTHUMG00000156661 +4233 MET MIM:164860|HGNC:HGNC:7029|Ensembl:ENSG00000105976|Vega:OTTHUMG00000023299 +4234 METTL1 MIM:604466|HGNC:HGNC:7030|Ensembl:ENSG00000037897|Vega:OTTHUMG00000150143 +4236 MFAP1 MIM:600215|HGNC:HGNC:7032|Ensembl:ENSG00000140259|Vega:OTTHUMG00000060145 +4237 MFAP2 MIM:156790|HGNC:HGNC:7033|Ensembl:ENSG00000117122|Vega:OTTHUMG00000002290 +4238 MFAP3 MIM:600491|HGNC:HGNC:7034|Ensembl:ENSG00000037749|Vega:OTTHUMG00000130149 +4239 MFAP4 MIM:600596|HGNC:HGNC:7035|Ensembl:ENSG00000166482|Vega:OTTHUMG00000059585 +4240 MFGE8 MIM:602281|HGNC:HGNC:7036|Ensembl:ENSG00000140545|Vega:OTTHUMG00000148682 +4241 MELTF MIM:155750|HGNC:HGNC:7037|Ensembl:ENSG00000163975|Vega:OTTHUMG00000155518 +4242 MFNG MIM:602577|HGNC:HGNC:7038|Ensembl:ENSG00000100060|Vega:OTTHUMG00000150560 +4245 MGAT1 MIM:160995|HGNC:HGNC:7044|Ensembl:ENSG00000131446|Vega:OTTHUMG00000130937 +4246 SCGB2A1 MIM:604398|HGNC:HGNC:7051|Ensembl:ENSG00000124939|Vega:OTTHUMG00000167506 +4247 MGAT2 MIM:602616|HGNC:HGNC:7045|Ensembl:ENSG00000168282|Vega:OTTHUMG00000140271 +4248 MGAT3 MIM:604621|HGNC:HGNC:7046|Ensembl:ENSG00000128268|Vega:OTTHUMG00000030185 +4249 MGAT5 MIM:601774|HGNC:HGNC:7049|Ensembl:ENSG00000152127|Vega:OTTHUMG00000131681 +4250 SCGB2A2 MIM:605562|HGNC:HGNC:7050|Ensembl:ENSG00000110484|Vega:OTTHUMG00000167509 +4253 MIA2 MIM:602132|HGNC:HGNC:18432|Ensembl:ENSG00000150526|Ensembl:ENSG00000150527|Vega:OTTHUMG00000028831|Vega:OTTHUMG00000140258 +4254 KITLG MIM:184745|HGNC:HGNC:6343|Ensembl:ENSG00000049130|Vega:OTTHUMG00000169888 +4255 MGMT MIM:156569|HGNC:HGNC:7059|Ensembl:ENSG00000170430|Vega:OTTHUMG00000019261 +4256 MGP MIM:154870|HGNC:HGNC:7060|Ensembl:ENSG00000111341|Vega:OTTHUMG00000168740 +4257 MGST1 MIM:138330|HGNC:HGNC:7061|Ensembl:ENSG00000008394|Vega:OTTHUMG00000168816 +4258 MGST2 MIM:601733|HGNC:HGNC:7063|Ensembl:ENSG00000085871|Vega:OTTHUMG00000133382 +4259 MGST3 MIM:604564|HGNC:HGNC:7064|Ensembl:ENSG00000143198|Vega:OTTHUMG00000034627 +4261 CIITA MIM:600005|HGNC:HGNC:7067|Ensembl:ENSG00000179583|Vega:OTTHUMG00000129753 +4264 MHS2 MIM:154275|HGNC:HGNC:7071 +4265 MHS4 MIM:600467|HGNC:HGNC:7073 +4266 MHS6 MIM:601888|HGNC:HGNC:7075 +4267 CD99 MIM:313470|MIM:450000|HGNC:HGNC:7082|Ensembl:ENSG00000002586|Vega:OTTHUMG00000021073 +4270 MIC7 MIM:108990|HGNC:HGNC:7088 +4273 MIC12 MIM:107254|HGNC:HGNC:7079 +4277 MICB MIM:602436|HGNC:HGNC:7091|Ensembl:ENSG00000204516|IMGT/GENE-DB:MICB|Vega:OTTHUMG00000031074 +4279 MICD HGNC:HGNC:7093 +4280 MICE HGNC:HGNC:7094 +4281 MID1 MIM:300552|HGNC:HGNC:7095|Ensembl:ENSG00000101871|Vega:OTTHUMG00000021127 +4282 MIF MIM:153620|HGNC:HGNC:7097|Ensembl:ENSG00000240972|Vega:OTTHUMG00000150773 +4283 CXCL9 MIM:601704|HGNC:HGNC:7098|Ensembl:ENSG00000138755|Vega:OTTHUMG00000160889 +4284 MIP MIM:154050|HGNC:HGNC:7103|Ensembl:ENSG00000135517|Vega:OTTHUMG00000170571 +4285 MIPEP MIM:602241|HGNC:HGNC:7104|Ensembl:ENSG00000027001|Vega:OTTHUMG00000016573 +4286 MITF MIM:156845|HGNC:HGNC:7105|Ensembl:ENSG00000187098|Vega:OTTHUMG00000149921 +4287 ATXN3 MIM:607047|HGNC:HGNC:7106|Ensembl:ENSG00000066427|Vega:OTTHUMG00000162212 +4288 MKI67 MIM:176741|HGNC:HGNC:7107|Ensembl:ENSG00000148773|Vega:OTTHUMG00000019255 +4289 MKLN1 MIM:605623|HGNC:HGNC:7109|Ensembl:ENSG00000128585|Vega:OTTHUMG00000154880 +4291 MLF1 MIM:601402|HGNC:HGNC:7125|Ensembl:ENSG00000178053|Vega:OTTHUMG00000158775 +4292 MLH1 MIM:120436|HGNC:HGNC:7127|Ensembl:ENSG00000076242|Vega:OTTHUMG00000130797 +4293 MAP3K9 MIM:600136|HGNC:HGNC:6861|Ensembl:ENSG00000006432|Vega:OTTHUMG00000171249 +4294 MAP3K10 MIM:600137|HGNC:HGNC:6849|Ensembl:ENSG00000130758|Vega:OTTHUMG00000182591 +4295 MLN MIM:158270|HGNC:HGNC:7141|Ensembl:ENSG00000096395|Vega:OTTHUMG00000014536 +4296 MAP3K11 MIM:600050|HGNC:HGNC:6850|Ensembl:ENSG00000173327|Vega:OTTHUMG00000166529 +4297 KMT2A MIM:159555|HGNC:HGNC:7132|Ensembl:ENSG00000118058|Vega:OTTHUMG00000166337 +4298 MLLT1 MIM:159556|HGNC:HGNC:7134|Ensembl:ENSG00000130382|Vega:OTTHUMG00000180757 +4299 AFF1 MIM:159557|HGNC:HGNC:7135|Ensembl:ENSG00000172493|Vega:OTTHUMG00000130603 +4300 MLLT3 MIM:159558|HGNC:HGNC:7136|Ensembl:ENSG00000171843|Vega:OTTHUMG00000019650 +4301 AFDN MIM:159559|HGNC:HGNC:7137|Ensembl:ENSG00000130396|Vega:OTTHUMG00000016031 +4302 MLLT6 MIM:600328|HGNC:HGNC:7138|Ensembl:ENSG00000275023|Vega:OTTHUMG00000188498 +4303 FOXO4 MIM:300033|HGNC:HGNC:7139|Ensembl:ENSG00000184481|Vega:OTTHUMG00000021789 +4306 NR3C2 MIM:600983|HGNC:HGNC:7979|Ensembl:ENSG00000151623|Vega:OTTHUMG00000161455 +4308 TRPM1 MIM:603576|HGNC:HGNC:7146|Ensembl:ENSG00000134160|Vega:OTTHUMG00000129267 +4309 MLVI2 MIM:157960 +4311 MME MIM:120520|HGNC:HGNC:7154|Ensembl:ENSG00000196549|Vega:OTTHUMG00000158455 +4312 MMP1 MIM:120353|HGNC:HGNC:7155|Ensembl:ENSG00000196611|Vega:OTTHUMG00000048192 +4313 MMP2 MIM:120360|HGNC:HGNC:7166|Ensembl:ENSG00000087245|Vega:OTTHUMG00000133202 +4314 MMP3 MIM:185250|HGNC:HGNC:7173|Ensembl:ENSG00000149968|Vega:OTTHUMG00000048254 +4316 MMP7 MIM:178990|HGNC:HGNC:7174|Ensembl:ENSG00000137673|Vega:OTTHUMG00000048193 +4317 MMP8 MIM:120355|HGNC:HGNC:7175|Ensembl:ENSG00000118113|Vega:OTTHUMG00000167587 +4318 MMP9 MIM:120361|HGNC:HGNC:7176|Ensembl:ENSG00000100985|Vega:OTTHUMG00000033044 +4319 MMP10 MIM:185260|HGNC:HGNC:7156|Ensembl:ENSG00000166670|Vega:OTTHUMG00000168083 +4320 MMP11 MIM:185261|HGNC:HGNC:7157|Ensembl:ENSG00000099953|Vega:OTTHUMG00000150742 +4321 MMP12 MIM:601046|HGNC:HGNC:7158|Ensembl:ENSG00000262406|Vega:OTTHUMG00000165848 +4322 MMP13 MIM:600108|HGNC:HGNC:7159|Ensembl:ENSG00000137745|Vega:OTTHUMG00000165850 +4323 MMP14 MIM:600754|HGNC:HGNC:7160|Ensembl:ENSG00000157227|Vega:OTTHUMG00000028704 +4324 MMP15 MIM:602261|HGNC:HGNC:7161|Ensembl:ENSG00000102996|Vega:OTTHUMG00000133466 +4325 MMP16 MIM:602262|HGNC:HGNC:7162|Ensembl:ENSG00000156103|Vega:OTTHUMG00000163769 +4326 MMP17 MIM:602285|HGNC:HGNC:7163|Ensembl:ENSG00000198598|Vega:OTTHUMG00000168050 +4327 MMP19 MIM:601807|HGNC:HGNC:7165|Ensembl:ENSG00000123342|Vega:OTTHUMG00000170216 +4329 ALDH6A1 MIM:603178|HGNC:HGNC:7179|Ensembl:ENSG00000119711|Vega:OTTHUMG00000171203 +4330 MN1 MIM:156100|HGNC:HGNC:7180|Ensembl:ENSG00000169184|Vega:OTTHUMG00000150975 +4331 MNAT1 MIM:602659|HGNC:HGNC:7181|Ensembl:ENSG00000020426|Vega:OTTHUMG00000152340 +4332 MNDA MIM:159553|HGNC:HGNC:7183|Ensembl:ENSG00000163563|Vega:OTTHUMG00000022776 +4335 MNT MIM:603039|HGNC:HGNC:7188|Ensembl:ENSG00000070444|Vega:OTTHUMG00000090603 +4336 MOBP MIM:600948|HGNC:HGNC:7189|Ensembl:ENSG00000168314|Vega:OTTHUMG00000131347 +4337 MOCS1 MIM:603707|HGNC:HGNC:7190|Ensembl:ENSG00000124615|Vega:OTTHUMG00000014656 +4338 MOCS2 MIM:603708|HGNC:HGNC:7193|Ensembl:ENSG00000164172|Vega:OTTHUMG00000096981 +4340 MOG MIM:159465|HGNC:HGNC:7197|Ensembl:ENSG00000204655|Vega:OTTHUMG00000031099 +4342 MOS MIM:190060|HGNC:HGNC:7199|Ensembl:ENSG00000172680|Vega:OTTHUMG00000164299 +4343 MOV10 MIM:610742|HGNC:HGNC:7200|Ensembl:ENSG00000155363|Vega:OTTHUMG00000011906 +4345 CD200 MIM:155970|HGNC:HGNC:7203|Ensembl:ENSG00000091972|Vega:OTTHUMG00000159248 +4350 MPG MIM:156565|HGNC:HGNC:7211|Ensembl:ENSG00000103152|Vega:OTTHUMG00000047887 +4351 MPI MIM:154550|HGNC:HGNC:7216|Ensembl:ENSG00000178802|Vega:OTTHUMG00000142826 +4352 MPL MIM:159530|HGNC:HGNC:7217|Ensembl:ENSG00000117400|Vega:OTTHUMG00000007429 +4353 MPO MIM:606989|HGNC:HGNC:7218|Ensembl:ENSG00000005381|Vega:OTTHUMG00000178922 +4354 MPP1 MIM:305360|HGNC:HGNC:7219|Ensembl:ENSG00000130830|Vega:OTTHUMG00000024244 +4355 MPP2 MIM:600723|HGNC:HGNC:7220|Ensembl:ENSG00000108852|Vega:OTTHUMG00000133840 +4356 MPP3 MIM:601114|HGNC:HGNC:7221|Ensembl:ENSG00000161647|Vega:OTTHUMG00000133838 +4357 MPST MIM:602496|HGNC:HGNC:7223|Ensembl:ENSG00000128309|Vega:OTTHUMG00000150543 +4358 MPV17 MIM:137960|HGNC:HGNC:7224|Ensembl:ENSG00000115204|Vega:OTTHUMG00000097074 +4359 MPZ MIM:159440|HGNC:HGNC:7225|Ensembl:ENSG00000158887|Vega:OTTHUMG00000034341 +4360 MRC1 MIM:153618|HGNC:HGNC:7228|Ensembl:ENSG00000260314|Vega:OTTHUMG00000174646 +4361 MRE11 MIM:600814|HGNC:HGNC:7230|Ensembl:ENSG00000020922|Vega:OTTHUMG00000167780 +4362 MRE11P1 HGNC:HGNC:7231 +4363 ABCC1 MIM:158343|HGNC:HGNC:51|Ensembl:ENSG00000103222|Vega:OTTHUMG00000048267 +4364 MRSD MIM:309620|HGNC:HGNC:7236 +4366 MRX4 HGNC:HGNC:7271 +4369 MRX5 HGNC:HGNC:7282 +4370 MRX6 HGNC:HGNC:7293 +4371 MRX7 HGNC:HGNC:7304 +4372 MRX8 HGNC:HGNC:7311 +4375 MRX11 HGNC:HGNC:7240 +4378 MRX14 MIM:300062|HGNC:HGNC:7243 +4379 MRX15 HGNC:HGNC:7244 +4381 MRX17 HGNC:HGNC:7246 +4382 MRX18 HGNC:HGNC:7247 +4384 MRX20 MIM:300047|HGNC:HGNC:7250 +4387 MRX23 MIM:300046|HGNC:HGNC:7253 +4388 MRX24 HGNC:HGNC:7254 +4389 MRX25 HGNC:HGNC:7255 +4390 MRX26 HGNC:HGNC:7256 +4391 MRX27 HGNC:HGNC:7257 +4392 MRX28 HGNC:HGNC:7258 +4395 MRX31 HGNC:HGNC:7262 +4397 MS MIM:126200|HGNC:HGNC:7314 +4402 MRX37 HGNC:HGNC:7268 +4404 MRX39 HGNC:HGNC:7270 +4405 MRX40 HGNC:HGNC:7272 +4406 MRX42 MIM:300372|HGNC:HGNC:7274 +4412 MRX49 MIM:300114|HGNC:HGNC:7281 +4413 MRX50 MIM:300115|HGNC:HGNC:7283 +4414 MRX51 HGNC:HGNC:7284 +4416 MRX53 MIM:300324|HGNC:HGNC:7286 +4419 MRX56 HGNC:HGNC:7289 +4420 MRX57 HGNC:HGNC:7290 +4424 MRX61 HGNC:HGNC:7295 +4427 MRX64 HGNC:HGNC:7298 +4428 MRX65 HGNC:HGNC:7299 +4429 MRXS7 MIM:300218|HGNC:HGNC:7313 +4430 MYO1B MIM:606537|HGNC:HGNC:7596|Ensembl:ENSG00000128641|Vega:OTTHUMG00000132718 +4431 MSBP1 HGNC:HGNC:7318 +4432 MSBP2 HGNC:HGNC:7319 +4434 MSD MIM:311400|HGNC:HGNC:7322 +4435 CITED1 MIM:300149|HGNC:HGNC:1986|Ensembl:ENSG00000125931|Vega:OTTHUMG00000021812 +4436 MSH2 MIM:609309|HGNC:HGNC:7325|Ensembl:ENSG00000095002|Vega:OTTHUMG00000128861 +4437 MSH3 MIM:600887|HGNC:HGNC:7326|Ensembl:ENSG00000113318|Vega:OTTHUMG00000162540 +4438 MSH4 MIM:602105|HGNC:HGNC:7327|Ensembl:ENSG00000057468|Vega:OTTHUMG00000009788 +4439 MSH5 MIM:603382|HGNC:HGNC:7328|Ensembl:ENSG00000204410|Vega:OTTHUMG00000167551 +4440 MSI1 MIM:603328|HGNC:HGNC:7330|Ensembl:ENSG00000135097|Vega:OTTHUMG00000169344 +4447 MSK9 HGNC:HGNC:7369 +4448 MSK10 HGNC:HGNC:7332 +4467 MSK32 HGNC:HGNC:7356 +4473 MSK38 HGNC:HGNC:7362 +4477 MSMB MIM:157145|HGNC:HGNC:7372|Ensembl:ENSG00000263639|Vega:OTTHUMG00000188315 +4478 MSN MIM:309845|HGNC:HGNC:7373|Ensembl:ENSG00000147065|Vega:OTTHUMG00000021723 +4479 MSNP1 HGNC:HGNC:7374 +4481 MSR1 MIM:153622|HGNC:HGNC:7376|Ensembl:ENSG00000038945|Vega:OTTHUMG00000094809 +4482 MSRA MIM:601250|HGNC:HGNC:7377|Ensembl:ENSG00000175806|Vega:OTTHUMG00000090517 +4485 MST1 MIM:142408|HGNC:HGNC:7380|Ensembl:ENSG00000173531|Vega:OTTHUMG00000155918 +4486 MST1R MIM:600168|HGNC:HGNC:7381|Ensembl:ENSG00000164078|Vega:OTTHUMG00000156709 +4487 MSX1 MIM:142983|HGNC:HGNC:7391|Ensembl:ENSG00000163132|Vega:OTTHUMG00000090335 +4488 MSX2 MIM:123101|HGNC:HGNC:7392|Ensembl:ENSG00000120149|Vega:OTTHUMG00000130556 +4489 MT1A MIM:156350|HGNC:HGNC:7393|Ensembl:ENSG00000205362|Vega:OTTHUMG00000176919 +4490 MT1B MIM:156349|HGNC:HGNC:7394|Ensembl:ENSG00000169688|Vega:OTTHUMG00000133277 +4493 MT1E MIM:156351|HGNC:HGNC:7397|Ensembl:ENSG00000169715|Vega:OTTHUMG00000133014 +4494 MT1F MIM:156352|HGNC:HGNC:7398|Ensembl:ENSG00000198417|Vega:OTTHUMG00000176838 +4495 MT1G MIM:156353|HGNC:HGNC:7399|Ensembl:ENSG00000125144|Vega:OTTHUMG00000133275 +4496 MT1H MIM:156354|HGNC:HGNC:7400|Ensembl:ENSG00000205358|Vega:OTTHUMG00000133283 +4498 MT1JP MIM:156356|HGNC:HGNC:7402|Ensembl:ENSG00000255986 +4499 MT1M MIM:156357|HGNC:HGNC:14296|Ensembl:ENSG00000205364|Vega:OTTHUMG00000176938 +4500 MT1L MIM:156358|HGNC:HGNC:7404|Ensembl:ENSG00000260549 +4501 MT1X MIM:156359|HGNC:HGNC:7405|Ensembl:ENSG00000187193|Vega:OTTHUMG00000133280 +4502 MT2A MIM:156360|HGNC:HGNC:7406|Ensembl:ENSG00000125148|Vega:OTTHUMG00000133281 +4503 MT2P1 HGNC:HGNC:7407 +4504 MT3 MIM:139255|HGNC:HGNC:7408|Ensembl:ENSG00000087250|Vega:OTTHUMG00000133282 +4507 MTAP MIM:156540|HGNC:HGNC:7413|Ensembl:ENSG00000099810|Vega:OTTHUMG00000019690 +4508 ATP6 MIM:516060|HGNC:HGNC:7414 +4509 ATP8 MIM:516070|HGNC:HGNC:7415 +4511 TRNC MIM:590020|HGNC:HGNC:7477 +4512 COX1 MIM:516030|HGNC:HGNC:7419 +4513 COX2 MIM:516040|HGNC:HGNC:7421 +4514 COX3 MIM:516050|HGNC:HGNC:7422 +4515 MTCP1 MIM:300116|HGNC:HGNC:7423|Ensembl:ENSG00000214827|Vega:OTTHUMG00000156241 +4519 CYTB MIM:516020|HGNC:HGNC:7427 +4520 MTF1 MIM:600172|HGNC:HGNC:7428|Ensembl:ENSG00000188786|Vega:OTTHUMG00000004439 +4521 NUDT1 MIM:600312|HGNC:HGNC:8048|Ensembl:ENSG00000106268|Vega:OTTHUMG00000023072 +4522 MTHFD1 MIM:172460|HGNC:HGNC:7432|Ensembl:ENSG00000100714|Vega:OTTHUMG00000141309 +4523 MTHFD1P1 HGNC:HGNC:7433 +4524 MTHFR MIM:607093|HGNC:HGNC:7436|Ensembl:ENSG00000177000|Vega:OTTHUMG00000002277 +4528 MTIF2 MIM:603766|HGNC:HGNC:7441|Ensembl:ENSG00000085760|Vega:OTTHUMG00000129338 +4531 MTL3P HGNC:HGNC:7444 +4534 MTM1 MIM:300415|HGNC:HGNC:7448|Ensembl:ENSG00000171100|Vega:OTTHUMG00000024158 +4535 ND1 MIM:516000|HGNC:HGNC:7455 +4536 ND2 MIM:516001|HGNC:HGNC:7456 +4537 ND3 MIM:516002|HGNC:HGNC:7458 +4538 ND4 MIM:516003|HGNC:HGNC:7459 +4539 ND4L MIM:516004|HGNC:HGNC:7460 +4540 ND5 MIM:516005|HGNC:HGNC:7461 +4541 ND6 MIM:516006|HGNC:HGNC:7462 +4542 MYO1F MIM:601480|HGNC:HGNC:7600|Ensembl:ENSG00000142347|Vega:OTTHUMG00000156005 +4543 MTNR1A MIM:600665|HGNC:HGNC:7463|Ensembl:ENSG00000168412|Vega:OTTHUMG00000185575 +4544 MTNR1B MIM:600804|HGNC:HGNC:7464|Ensembl:ENSG00000134640|Vega:OTTHUMG00000167364 +4547 MTTP MIM:157147|HGNC:HGNC:7467|Ensembl:ENSG00000138823|Vega:OTTHUMG00000131023 +4548 MTR MIM:156570|HGNC:HGNC:7468|Ensembl:ENSG00000116984|Vega:OTTHUMG00000040060 +4549 RNR1 MIM:561000|HGNC:HGNC:7470 +4550 RNR2 MIM:561010|HGNC:HGNC:7471 +4552 MTRR MIM:602568|HGNC:HGNC:7473|Ensembl:ENSG00000124275|Vega:OTTHUMG00000090477 +4553 TRNA MIM:590000|HGNC:HGNC:7475 +4555 TRND MIM:590015|HGNC:HGNC:7478 +4556 TRNE MIM:590025|HGNC:HGNC:7479 +4558 TRNF MIM:590070|HGNC:HGNC:7481 +4563 TRNG MIM:590035|HGNC:HGNC:7486 +4564 TRNH MIM:590040|HGNC:HGNC:7487 +4565 TRNI MIM:590045|HGNC:HGNC:7488 +4566 TRNK MIM:590060|HGNC:HGNC:7489 +4567 TRNL1 MIM:590050|HGNC:HGNC:7490 +4568 TRNL2 MIM:590055|HGNC:HGNC:7491 +4569 TRNM MIM:590065|HGNC:HGNC:7492 +4570 TRNN MIM:590010|HGNC:HGNC:7493 +4571 TRNP MIM:590075|HGNC:HGNC:7494 +4572 TRNQ MIM:590030|HGNC:HGNC:7495 +4573 TRNR MIM:590005|HGNC:HGNC:7496 +4574 TRNS1 MIM:590080|HGNC:HGNC:7497 +4575 TRNS2 MIM:590085|HGNC:HGNC:7498 +4576 TRNT MIM:590090|HGNC:HGNC:7499 +4577 TRNV MIM:590105|HGNC:HGNC:7500 +4578 TRNW MIM:590095|HGNC:HGNC:7501 +4579 TRNY MIM:590100|HGNC:HGNC:7502 +4580 MTX1 MIM:600605|HGNC:HGNC:7504|Ensembl:ENSG00000173171|Vega:OTTHUMG00000035708 +4581 MTX1P1 HGNC:HGNC:7505 +4582 MUC1 MIM:158340|HGNC:HGNC:7508|Ensembl:ENSG00000185499|Vega:OTTHUMG00000035681 +4583 MUC2 MIM:158370|HGNC:HGNC:7512 +4584 MUC3A MIM:158371|HGNC:HGNC:7513|Ensembl:ENSG00000169894|Vega:OTTHUMG00000157038 +4585 MUC4 MIM:158372|HGNC:HGNC:7514|Ensembl:ENSG00000145113|Vega:OTTHUMG00000151827 +4586 MUC5AC MIM:158373|HGNC:HGNC:7515|Ensembl:ENSG00000215182|Vega:OTTHUMG00000154270 +4588 MUC6 MIM:158374|HGNC:HGNC:7517|Ensembl:ENSG00000184956|Vega:OTTHUMG00000165140 +4589 MUC7 MIM:158375|HGNC:HGNC:7518|Ensembl:ENSG00000171195|Vega:OTTHUMG00000129916 +4591 TRIM37 MIM:605073|HGNC:HGNC:7523|Ensembl:ENSG00000108395|Vega:OTTHUMG00000179360 +4593 MUSK MIM:601296|HGNC:HGNC:7525|Ensembl:ENSG00000030304|Vega:OTTHUMG00000020485 +4594 MUT MIM:609058|HGNC:HGNC:7526|Ensembl:ENSG00000146085|Vega:OTTHUMG00000014814 +4595 MUTYH MIM:604933|HGNC:HGNC:7527|Ensembl:ENSG00000132781|Vega:OTTHUMG00000007682 +4597 MVD MIM:603236|HGNC:HGNC:7529|Ensembl:ENSG00000167508|Vega:OTTHUMG00000137865 +4598 MVK MIM:251170|HGNC:HGNC:7530|Ensembl:ENSG00000110921|Vega:OTTHUMG00000169256 +4599 MX1 MIM:147150|HGNC:HGNC:7532|Ensembl:ENSG00000157601|Vega:OTTHUMG00000086755 +4600 MX2 MIM:147890|HGNC:HGNC:7533|Ensembl:ENSG00000183486|Vega:OTTHUMG00000086753 +4601 MXI1 MIM:600020|HGNC:HGNC:7534|Ensembl:ENSG00000119950|Vega:OTTHUMG00000019033 +4602 MYB MIM:189990|HGNC:HGNC:7545|Ensembl:ENSG00000118513|Vega:OTTHUMG00000015629 +4603 MYBL1 MIM:159405|HGNC:HGNC:7547|Ensembl:ENSG00000185697|Vega:OTTHUMG00000164559 +4604 MYBPC1 MIM:160794|HGNC:HGNC:7549|Ensembl:ENSG00000196091|Vega:OTTHUMG00000170274 +4605 MYBL2 MIM:601415|HGNC:HGNC:7548|Ensembl:ENSG00000101057|Vega:OTTHUMG00000033062 +4606 MYBPC2 MIM:160793|HGNC:HGNC:7550|Ensembl:ENSG00000086967|Vega:OTTHUMG00000183040 +4607 MYBPC3 MIM:600958|HGNC:HGNC:7551|Ensembl:ENSG00000134571|Vega:OTTHUMG00000166986 +4608 MYBPH MIM:160795|HGNC:HGNC:7552|Ensembl:ENSG00000133055|Vega:OTTHUMG00000042121 +4609 MYC MIM:190080|HGNC:HGNC:7553|Ensembl:ENSG00000136997|Vega:OTTHUMG00000128475 +4610 MYCL MIM:164850|HGNC:HGNC:7555|Ensembl:ENSG00000116990|Vega:OTTHUMG00000009243 +4611 MYCLP1 MIM:310310|HGNC:HGNC:7556 +4613 MYCN MIM:164840|HGNC:HGNC:7559|Ensembl:ENSG00000134323|Vega:OTTHUMG00000039579 +4615 MYD88 MIM:602170|HGNC:HGNC:7562|Ensembl:ENSG00000172936|Vega:OTTHUMG00000131083 +4616 GADD45B MIM:604948|HGNC:HGNC:4096|Ensembl:ENSG00000099860|Vega:OTTHUMG00000180434 +4617 MYF5 MIM:159990|HGNC:HGNC:7565|Ensembl:ENSG00000111049|Vega:OTTHUMG00000170166 +4618 MYF6 MIM:159991|HGNC:HGNC:7566|Ensembl:ENSG00000111046|Vega:OTTHUMG00000170165 +4619 MYH1 MIM:160730|HGNC:HGNC:7567|Ensembl:ENSG00000109061|Vega:OTTHUMG00000130362 +4620 MYH2 MIM:160740|HGNC:HGNC:7572|Ensembl:ENSG00000125414|Vega:OTTHUMG00000130363 +4621 MYH3 MIM:160720|HGNC:HGNC:7573|Ensembl:ENSG00000109063|Vega:OTTHUMG00000130367 +4622 MYH4 MIM:160742|HGNC:HGNC:7574|Ensembl:ENSG00000264424|Vega:OTTHUMG00000130365 +4624 MYH6 MIM:160710|HGNC:HGNC:7576|Ensembl:ENSG00000197616|Vega:OTTHUMG00000028753 +4625 MYH7 MIM:160760|HGNC:HGNC:7577|Ensembl:ENSG00000092054|Vega:OTTHUMG00000028755 +4626 MYH8 MIM:160741|HGNC:HGNC:7578|Ensembl:ENSG00000133020|Vega:OTTHUMG00000130361 +4627 MYH9 MIM:160775|HGNC:HGNC:7579|Ensembl:ENSG00000100345|Vega:OTTHUMG00000030429 +4628 MYH10 MIM:160776|HGNC:HGNC:7568|Ensembl:ENSG00000133026|Vega:OTTHUMG00000108195 +4629 MYH11 MIM:160745|HGNC:HGNC:7569|Ensembl:ENSG00000133392|Vega:OTTHUMG00000129935 +4632 MYL1 MIM:160780|HGNC:HGNC:7582|Ensembl:ENSG00000168530|Vega:OTTHUMG00000132992 +4633 MYL2 MIM:160781|HGNC:HGNC:7583|Ensembl:ENSG00000111245|Vega:OTTHUMG00000169535 +4634 MYL3 MIM:160790|HGNC:HGNC:7584|Ensembl:ENSG00000160808|Vega:OTTHUMG00000133516 +4635 MYL4 MIM:160770|HGNC:HGNC:7585|Ensembl:ENSG00000198336|Vega:OTTHUMG00000178232 +4636 MYL5 MIM:160782|HGNC:HGNC:7586|Ensembl:ENSG00000215375|Vega:OTTHUMG00000159971 +4637 MYL6 MIM:609931|HGNC:HGNC:7587|Ensembl:ENSG00000092841|Vega:OTTHUMG00000170200 +4638 MYLK MIM:600922|HGNC:HGNC:7590|Ensembl:ENSG00000065534|Vega:OTTHUMG00000141304 +4640 MYO1A MIM:601478|HGNC:HGNC:7595|Ensembl:ENSG00000166866|Vega:OTTHUMG00000149899 +4641 MYO1C MIM:606538|HGNC:HGNC:7597|Ensembl:ENSG00000197879|Vega:OTTHUMG00000090323 +4642 MYO1D MIM:606539|HGNC:HGNC:7598|Ensembl:ENSG00000176658|Vega:OTTHUMG00000179636 +4643 MYO1E MIM:601479|HGNC:HGNC:7599|Ensembl:ENSG00000157483|Vega:OTTHUMG00000171944 +4644 MYO5A MIM:160777|HGNC:HGNC:7602|Ensembl:ENSG00000197535|Vega:OTTHUMG00000137383 +4645 MYO5B MIM:606540|HGNC:HGNC:7603|Ensembl:ENSG00000167306|Vega:OTTHUMG00000179843 +4646 MYO6 MIM:600970|HGNC:HGNC:7605|Ensembl:ENSG00000196586|Vega:OTTHUMG00000015061 +4647 MYO7A MIM:276903|HGNC:HGNC:7606|Ensembl:ENSG00000137474|Vega:OTTHUMG00000152822 +4648 MYO7B MIM:606541|HGNC:HGNC:7607|Ensembl:ENSG00000169994|Vega:OTTHUMG00000153419 +4649 MYO9A MIM:604875|HGNC:HGNC:7608|Ensembl:ENSG00000066933|Vega:OTTHUMG00000133440 +4650 MYO9B MIM:602129|HGNC:HGNC:7609|Ensembl:ENSG00000099331|Vega:OTTHUMG00000182707 +4651 MYO10 MIM:601481|HGNC:HGNC:7593|Ensembl:ENSG00000145555|Vega:OTTHUMG00000161822 +4653 MYOC MIM:601652|HGNC:HGNC:7610|Ensembl:ENSG00000034971|Vega:OTTHUMG00000034789 +4654 MYOD1 MIM:159970|HGNC:HGNC:7611|Ensembl:ENSG00000129152|Vega:OTTHUMG00000166358 +4655 MYSA HGNC:HGNC:7620 +4656 MYOG MIM:159980|HGNC:HGNC:7612|Ensembl:ENSG00000122180|Vega:OTTHUMG00000042127 +4657 MYP1 MIM:310460|HGNC:HGNC:7615 +4658 MYP2 MIM:160700|HGNC:HGNC:7616 +4659 PPP1R12A MIM:602021|HGNC:HGNC:7618|Ensembl:ENSG00000058272|Vega:OTTHUMG00000170100 +4660 PPP1R12B MIM:603768|HGNC:HGNC:7619|Ensembl:ENSG00000077157|Vega:OTTHUMG00000041393 +4661 MYT1 MIM:600379|HGNC:HGNC:7622|Ensembl:ENSG00000196132|Vega:OTTHUMG00000149988 +4664 NAB1 MIM:600800|HGNC:HGNC:7626|Ensembl:ENSG00000138386|Vega:OTTHUMG00000132689 +4665 NAB2 MIM:602381|HGNC:HGNC:7627|Ensembl:ENSG00000166886|Vega:OTTHUMG00000171192 +4666 NACA MIM:601234|HGNC:HGNC:7629|Ensembl:ENSG00000196531|Vega:OTTHUMG00000170033 +4668 NAGA MIM:104170|HGNC:HGNC:7631|Ensembl:ENSG00000198951|Vega:OTTHUMG00000151276 +4669 NAGLU MIM:609701|HGNC:HGNC:7632|Ensembl:ENSG00000108784|Vega:OTTHUMG00000180240 +4670 HNRNPM MIM:160994|HGNC:HGNC:5046|Ensembl:ENSG00000099783|Vega:OTTHUMG00000182383 +4671 NAIP MIM:600355|HGNC:HGNC:7634|Ensembl:ENSG00000249437|Vega:OTTHUMG00000163318 +4673 NAP1L1 MIM:164060|HGNC:HGNC:7637|Ensembl:ENSG00000187109|Vega:OTTHUMG00000169786 +4674 NAP1L2 MIM:300026|HGNC:HGNC:7638|Ensembl:ENSG00000186462|Vega:OTTHUMG00000021827 +4675 NAP1L3 MIM:300117|HGNC:HGNC:7639|Ensembl:ENSG00000186310|Vega:OTTHUMG00000021974 +4676 NAP1L4 MIM:601651|HGNC:HGNC:7640|Ensembl:ENSG00000205531|Vega:OTTHUMG00000011009 +4677 NARS MIM:108410|HGNC:HGNC:7643|Ensembl:ENSG00000134440|Vega:OTTHUMG00000180125 +4678 NASP MIM:603185|HGNC:HGNC:7644|Ensembl:ENSG00000132780|Vega:OTTHUMG00000007826 +4680 CEACAM6 MIM:163980|HGNC:HGNC:1818|Ensembl:ENSG00000086548|Vega:OTTHUMG00000151064 +4681 NBL1 MIM:600613|HGNC:HGNC:7650|Ensembl:ENSG00000158747|Vega:OTTHUMG00000002700 +4682 NUBP1 MIM:600280|HGNC:HGNC:8041|Ensembl:ENSG00000103274|Vega:OTTHUMG00000129751 +4683 NBN MIM:602667|HGNC:HGNC:7652|Ensembl:ENSG00000104320|Vega:OTTHUMG00000153546 +4684 NCAM1 MIM:116930|HGNC:HGNC:7656|Ensembl:ENSG00000149294|Vega:OTTHUMG00000167196 +4685 NCAM2 MIM:602040|HGNC:HGNC:7657|Ensembl:ENSG00000154654|Vega:OTTHUMG00000078121 +4686 NCBP1 MIM:600469|HGNC:HGNC:7658|Ensembl:ENSG00000136937|Vega:OTTHUMG00000020332 +4688 NCF2 MIM:608515|HGNC:HGNC:7661|Ensembl:ENSG00000116701|Vega:OTTHUMG00000035329 +4689 NCF4 MIM:601488|HGNC:HGNC:7662|Ensembl:ENSG00000100365|Vega:OTTHUMG00000150548 +4690 NCK1 MIM:600508|HGNC:HGNC:7664|Ensembl:ENSG00000158092|Vega:OTTHUMG00000159781 +4691 NCL MIM:164035|HGNC:HGNC:7667|Ensembl:ENSG00000115053|Vega:OTTHUMG00000153866 +4692 NDN MIM:602117|HGNC:HGNC:7675|Ensembl:ENSG00000182636|Vega:OTTHUMG00000129161 +4693 NDP MIM:300658|HGNC:HGNC:7678|Ensembl:ENSG00000124479|Vega:OTTHUMG00000021391 +4694 NDUFA1 MIM:300078|HGNC:HGNC:7683|Ensembl:ENSG00000125356|Vega:OTTHUMG00000022287 +4695 NDUFA2 MIM:602137|HGNC:HGNC:7685|Ensembl:ENSG00000131495|Vega:OTTHUMG00000129505 +4696 NDUFA3 MIM:603832|HGNC:HGNC:7686|Ensembl:ENSG00000170906|Vega:OTTHUMG00000064972 +4697 NDUFA4 MIM:603833|HGNC:HGNC:7687|Ensembl:ENSG00000189043|Vega:OTTHUMG00000023880 +4698 NDUFA5 MIM:601677|HGNC:HGNC:7688|Ensembl:ENSG00000128609|Vega:OTTHUMG00000157348 +4699 NDUFA5P1 HGNC:HGNC:7689 +4700 NDUFA6 MIM:602138|HGNC:HGNC:7690|Ensembl:ENSG00000184983|Vega:OTTHUMG00000151287 +4701 NDUFA7 MIM:602139|HGNC:HGNC:7691|Ensembl:ENSG00000167774|Ensembl:ENSG00000267855|Vega:OTTHUMG00000182458|Vega:OTTHUMG00000182459 +4702 NDUFA8 MIM:603359|HGNC:HGNC:7692|Ensembl:ENSG00000119421|Vega:OTTHUMG00000020598 +4703 NEB MIM:161650|HGNC:HGNC:7720|Ensembl:ENSG00000183091|Vega:OTTHUMG00000153784 +4704 NDUFA9 MIM:603834|HGNC:HGNC:7693|Ensembl:ENSG00000139180|Vega:OTTHUMG00000168224 +4705 NDUFA10 MIM:603835|HGNC:HGNC:7684|Ensembl:ENSG00000130414|Vega:OTTHUMG00000133350 +4706 NDUFAB1 MIM:603836|HGNC:HGNC:7694|Ensembl:ENSG00000004779|Vega:OTTHUMG00000096985 +4707 NDUFB1 MIM:603837|HGNC:HGNC:7695|Ensembl:ENSG00000183648|Vega:OTTHUMG00000171180 +4708 NDUFB2 MIM:603838|HGNC:HGNC:7697|Ensembl:ENSG00000090266|Vega:OTTHUMG00000157424 +4709 NDUFB3 MIM:603839|HGNC:HGNC:7698|Ensembl:ENSG00000119013|Vega:OTTHUMG00000132820 +4710 NDUFB4 MIM:603840|HGNC:HGNC:7699|Ensembl:ENSG00000065518|Vega:OTTHUMG00000159442 +4711 NDUFB5 MIM:603841|HGNC:HGNC:7700|Ensembl:ENSG00000136521|Vega:OTTHUMG00000157480 +4712 NDUFB6 MIM:603322|HGNC:HGNC:7701|Ensembl:ENSG00000165264|Vega:OTTHUMG00000019741 +4713 NDUFB7 MIM:603842|HGNC:HGNC:7702|Ensembl:ENSG00000099795|Vega:OTTHUMG00000183291 +4714 NDUFB8 MIM:602140|HGNC:HGNC:7703|Ensembl:ENSG00000166136|Ensembl:ENSG00000255339|Vega:OTTHUMG00000019346|Vega:OTTHUMG00000166603 +4715 NDUFB9 MIM:601445|HGNC:HGNC:7704|Ensembl:ENSG00000147684|Vega:OTTHUMG00000165054 +4716 NDUFB10 MIM:603843|HGNC:HGNC:7696|Ensembl:ENSG00000140990|Vega:OTTHUMG00000128709 +4717 NDUFC1 MIM:603844|HGNC:HGNC:7705|Ensembl:ENSG00000109390|Vega:OTTHUMG00000133387 +4718 NDUFC2 MIM:603845|HGNC:HGNC:7706|Ensembl:ENSG00000151366|Vega:OTTHUMG00000166614 +4719 NDUFS1 MIM:157655|HGNC:HGNC:7707|Ensembl:ENSG00000023228|Vega:OTTHUMG00000132892 +4720 NDUFS2 MIM:602985|HGNC:HGNC:7708|Ensembl:ENSG00000158864|Vega:OTTHUMG00000034344 +4722 NDUFS3 MIM:603846|HGNC:HGNC:7710|Ensembl:ENSG00000213619|Vega:OTTHUMG00000166893 +4723 NDUFV1 MIM:161015|HGNC:HGNC:7716|Ensembl:ENSG00000167792|Vega:OTTHUMG00000166215 +4724 NDUFS4 MIM:602694|HGNC:HGNC:7711|Ensembl:ENSG00000164258|Vega:OTTHUMG00000096987 +4725 NDUFS5 MIM:603847|HGNC:HGNC:7712|Ensembl:ENSG00000168653|Vega:OTTHUMG00000007497 +4726 NDUFS6 MIM:603848|HGNC:HGNC:7713|Ensembl:ENSG00000145494|Vega:OTTHUMG00000090372 +4728 NDUFS8 MIM:602141|HGNC:HGNC:7715|Ensembl:ENSG00000110717|Vega:OTTHUMG00000167331 +4729 NDUFV2 MIM:600532|HGNC:HGNC:7717|Ensembl:ENSG00000178127|Vega:OTTHUMG00000131593 +4730 NDUFV2P1 HGNC:HGNC:7718 +4731 NDUFV3 MIM:602184|HGNC:HGNC:7719|Ensembl:ENSG00000160194|Vega:OTTHUMG00000086823 +4733 DRG1 MIM:603952|HGNC:HGNC:3029|Ensembl:ENSG00000185721|Vega:OTTHUMG00000030792 +4734 NEDD4 MIM:602278|HGNC:HGNC:7727|Ensembl:ENSG00000069869|Vega:OTTHUMG00000132015 +4735 SEPT2 MIM:601506|HGNC:HGNC:7729|Ensembl:ENSG00000168385|Vega:OTTHUMG00000133394 +4736 RPL10A MIM:615660|HGNC:HGNC:10299|Ensembl:ENSG00000198755|Vega:OTTHUMG00000014566 +4738 NEDD8 MIM:603171|HGNC:HGNC:7732|Ensembl:ENSG00000129559|Vega:OTTHUMG00000029325 +4739 NEDD9 MIM:602265|HGNC:HGNC:7733|Ensembl:ENSG00000111859|Vega:OTTHUMG00000014255 +4741 NEFM MIM:162250|HGNC:HGNC:7734|Ensembl:ENSG00000104722|Vega:OTTHUMG00000131990 +4744 NEFH MIM:162230|HGNC:HGNC:7737|Ensembl:ENSG00000100285|Vega:OTTHUMG00000151155 +4745 NELL1 MIM:602319|HGNC:HGNC:7750|Ensembl:ENSG00000165973|Vega:OTTHUMG00000166042 +4747 NEFL MIM:162280|HGNC:HGNC:7739|Ensembl:ENSG00000277586|Vega:OTTHUMG00000134284 +4750 NEK1 MIM:604588|HGNC:HGNC:7744|Ensembl:ENSG00000137601|Vega:OTTHUMG00000160963 +4751 NEK2 MIM:604043|HGNC:HGNC:7745|Ensembl:ENSG00000117650|Vega:OTTHUMG00000037121 +4752 NEK3 MIM:604044|HGNC:HGNC:7746|Ensembl:ENSG00000136098|Vega:OTTHUMG00000016958 +4753 NELL2 MIM:602320|HGNC:HGNC:7751|Ensembl:ENSG00000184613|Vega:OTTHUMG00000169464 +4756 NEO1 MIM:601907|HGNC:HGNC:7754|Ensembl:ENSG00000067141|Vega:OTTHUMG00000133509 +4758 NEU1 MIM:608272|HGNC:HGNC:7758|Ensembl:ENSG00000204386|Vega:OTTHUMG00000031284 +4759 NEU2 MIM:605528|HGNC:HGNC:7759|Ensembl:ENSG00000115488|Vega:OTTHUMG00000133274 +4760 NEUROD1 MIM:601724|HGNC:HGNC:7762|Ensembl:ENSG00000162992|Vega:OTTHUMG00000132583 +4761 NEUROD2 MIM:601725|HGNC:HGNC:7763|Ensembl:ENSG00000171532|Vega:OTTHUMG00000133211 +4762 NEUROG1 MIM:601726|HGNC:HGNC:7764|Ensembl:ENSG00000181965|Vega:OTTHUMG00000129138 +4763 NF1 MIM:613113|HGNC:HGNC:7765|Ensembl:ENSG00000196712|Vega:OTTHUMG00000132871 +4764 NF1P3 HGNC:HGNC:7766 +4768 NF1P5 HGNC:HGNC:7770 +4771 NF2 MIM:607379|HGNC:HGNC:7773|Ensembl:ENSG00000186575|Vega:OTTHUMG00000030727 +4772 NFATC1 MIM:600489|HGNC:HGNC:7775|Ensembl:ENSG00000131196|Vega:OTTHUMG00000132897 +4773 NFATC2 MIM:600490|HGNC:HGNC:7776|Ensembl:ENSG00000101096|Vega:OTTHUMG00000032747 +4774 NFIA MIM:600727|HGNC:HGNC:7784|Ensembl:ENSG00000162599|Vega:OTTHUMG00000008618 +4775 NFATC3 MIM:602698|HGNC:HGNC:7777|Ensembl:ENSG00000072736|Vega:OTTHUMG00000137555 +4776 NFATC4 MIM:602699|HGNC:HGNC:7778|Ensembl:ENSG00000100968|Vega:OTTHUMG00000029351 +4778 NFE2 MIM:601490|HGNC:HGNC:7780|Ensembl:ENSG00000123405|Vega:OTTHUMG00000169761 +4779 NFE2L1 MIM:163260|HGNC:HGNC:7781|Ensembl:ENSG00000082641|Vega:OTTHUMG00000178706 +4780 NFE2L2 MIM:600492|HGNC:HGNC:7782|Ensembl:ENSG00000116044|Vega:OTTHUMG00000133620 +4781 NFIB MIM:600728|HGNC:HGNC:7785|Ensembl:ENSG00000147862|Vega:OTTHUMG00000021027 +4782 NFIC MIM:600729|HGNC:HGNC:7786|Ensembl:ENSG00000141905|Vega:OTTHUMG00000180731 +4783 NFIL3 MIM:605327|HGNC:HGNC:7787|Ensembl:ENSG00000165030|Vega:OTTHUMG00000020209 +4784 NFIX MIM:164005|HGNC:HGNC:7788|Ensembl:ENSG00000008441|Vega:OTTHUMG00000180726 +4790 NFKB1 MIM:164011|HGNC:HGNC:7794|Ensembl:ENSG00000109320|Vega:OTTHUMG00000161080 +4791 NFKB2 MIM:164012|HGNC:HGNC:7795|Ensembl:ENSG00000077150|Vega:OTTHUMG00000018962 +4792 NFKBIA MIM:164008|HGNC:HGNC:7797|Ensembl:ENSG00000100906|Vega:OTTHUMG00000140220 +4793 NFKBIB MIM:604495|HGNC:HGNC:7798|Ensembl:ENSG00000104825|Vega:OTTHUMG00000177631 +4794 NFKBIE MIM:604548|HGNC:HGNC:7799|Ensembl:ENSG00000146232|Vega:OTTHUMG00000014762 +4795 NFKBIL1 MIM:601022|HGNC:HGNC:7800|Ensembl:ENSG00000204498|Vega:OTTHUMG00000031038 +4796 TONSL MIM:604546|HGNC:HGNC:7801|Ensembl:ENSG00000160949|Vega:OTTHUMG00000153122 +4798 NFRKB MIM:164013|HGNC:HGNC:7802|Ensembl:ENSG00000170322|Vega:OTTHUMG00000165761 +4799 NFX1 MIM:603255|HGNC:HGNC:7803|Ensembl:ENSG00000086102|Vega:OTTHUMG00000019772 +4800 NFYA MIM:189903|HGNC:HGNC:7804|Ensembl:ENSG00000001167|Vega:OTTHUMG00000014669 +4801 NFYB MIM:189904|HGNC:HGNC:7805|Ensembl:ENSG00000120837|Vega:OTTHUMG00000170176 +4802 NFYC MIM:605344|HGNC:HGNC:7806|Ensembl:ENSG00000066136|Vega:OTTHUMG00000007729 +4803 NGF MIM:162030|HGNC:HGNC:7808|Ensembl:ENSG00000134259|Vega:OTTHUMG00000011880 +4804 NGFR MIM:162010|HGNC:HGNC:7809|Ensembl:ENSG00000064300|Vega:OTTHUMG00000161495 +4805 NHCP1 MIM:118870|HGNC:HGNC:7811 +4807 NHLH1 MIM:162360|HGNC:HGNC:7817|Ensembl:ENSG00000171786|Vega:OTTHUMG00000033121 +4808 NHLH2 MIM:162361|HGNC:HGNC:7818|Ensembl:ENSG00000177551|Vega:OTTHUMG00000011969 +4809 SNU13 MIM:601304|HGNC:HGNC:7819|Ensembl:ENSG00000100138|Vega:OTTHUMG00000151189 +4810 NHS MIM:300457|HGNC:HGNC:7820|Ensembl:ENSG00000188158|Vega:OTTHUMG00000022799 +4811 NID1 MIM:131390|HGNC:HGNC:7821|Ensembl:ENSG00000116962|Vega:OTTHUMG00000040071 +4812 NIDDM1 MIM:601283|HGNC:HGNC:7822 +4813 NIDDM2 MIM:601407|HGNC:HGNC:7823 +4814 NINJ1 MIM:602062|HGNC:HGNC:7824|Ensembl:ENSG00000131669|Vega:OTTHUMG00000020242 +4815 NINJ2 MIM:607297|HGNC:HGNC:7825|Ensembl:ENSG00000171840|Vega:OTTHUMG00000090311 +4817 NIT1 MIM:604618|HGNC:HGNC:7828|Ensembl:ENSG00000158793|Vega:OTTHUMG00000031473 +4818 NKG7 MIM:606008|HGNC:HGNC:7830|Ensembl:ENSG00000105374|Vega:OTTHUMG00000182898 +4819 NKS1 MIM:272370|HGNC:HGNC:7832 +4820 NKTR MIM:161565|HGNC:HGNC:7833|Ensembl:ENSG00000114857|Vega:OTTHUMG00000133037 +4821 NKX2-2 MIM:604612|HGNC:HGNC:7835|Ensembl:ENSG00000125820|Vega:OTTHUMG00000170524 +4824 NKX3-1 MIM:602041|HGNC:HGNC:7838|Ensembl:ENSG00000167034|Vega:OTTHUMG00000097851 +4825 NKX6-1 MIM:602563|HGNC:HGNC:7839|Ensembl:ENSG00000163623|Vega:OTTHUMG00000130426 +4826 NNAT MIM:603106|HGNC:HGNC:7860|Ensembl:ENSG00000053438|Vega:OTTHUMG00000032420 +4827 NM MIM:162820|HGNC:HGNC:7841 +4828 NMB MIM:162340|HGNC:HGNC:7842|Ensembl:ENSG00000197696|Vega:OTTHUMG00000148666 +4829 NMBR MIM:162341|HGNC:HGNC:7843|Ensembl:ENSG00000135577|Vega:OTTHUMG00000015704 +4830 NME1 MIM:156490|HGNC:HGNC:7849|Ensembl:ENSG00000239672|Vega:OTTHUMG00000137474 +4831 NME2 MIM:156491|HGNC:HGNC:7850|Ensembl:ENSG00000243678|Vega:OTTHUMG00000154062 +4832 NME3 MIM:601817|HGNC:HGNC:7851|Ensembl:ENSG00000103024|Vega:OTTHUMG00000128635 +4833 NME4 MIM:601818|HGNC:HGNC:7852|Ensembl:ENSG00000103202|Vega:OTTHUMG00000047995 +4835 NQO2 MIM:160998|HGNC:HGNC:7856|Ensembl:ENSG00000124588|Vega:OTTHUMG00000014130 +4836 NMT1 MIM:160993|HGNC:HGNC:7857|Ensembl:ENSG00000136448|Vega:OTTHUMG00000180003 +4837 NNMT MIM:600008|HGNC:HGNC:7861|Ensembl:ENSG00000166741|Vega:OTTHUMG00000168245 +4838 NODAL MIM:601265|HGNC:HGNC:7865|Ensembl:ENSG00000156574|Vega:OTTHUMG00000018408 +4839 NOP2 MIM:164031|HGNC:HGNC:7867|Ensembl:ENSG00000111641|Vega:OTTHUMG00000169163 +4841 NONO MIM:300084|HGNC:HGNC:7871|Ensembl:ENSG00000147140|Vega:OTTHUMG00000021798 +4842 NOS1 MIM:163731|HGNC:HGNC:7872|Ensembl:ENSG00000089250|Vega:OTTHUMG00000137376 +4843 NOS2 MIM:163730|HGNC:HGNC:7873|Ensembl:ENSG00000007171|Vega:OTTHUMG00000132445 +4846 NOS3 MIM:163729|HGNC:HGNC:7876|Ensembl:ENSG00000164867|Vega:OTTHUMG00000158343 +4848 CNOT2 MIM:604909|HGNC:HGNC:7878|Ensembl:ENSG00000111596|Vega:OTTHUMG00000169481 +4849 CNOT3 MIM:604910|HGNC:HGNC:7879|Ensembl:ENSG00000088038|Vega:OTTHUMG00000066468 +4850 CNOT4 MIM:604911|HGNC:HGNC:7880|Ensembl:ENSG00000080802|Vega:OTTHUMG00000155568 +4851 NOTCH1 MIM:190198|HGNC:HGNC:7881|Ensembl:ENSG00000148400|Vega:OTTHUMG00000020935 +4852 NPY MIM:162640|HGNC:HGNC:7955|Ensembl:ENSG00000122585|Vega:OTTHUMG00000022973 +4853 NOTCH2 MIM:600275|HGNC:HGNC:7882|Ensembl:ENSG00000134250|Vega:OTTHUMG00000012177 +4854 NOTCH3 MIM:600276|HGNC:HGNC:7883|Ensembl:ENSG00000074181|Vega:OTTHUMG00000183217 +4855 NOTCH4 MIM:164951|HGNC:HGNC:7884|Ensembl:ENSG00000204301|Vega:OTTHUMG00000031044 +4856 NOV MIM:164958|HGNC:HGNC:7885|Ensembl:ENSG00000136999|Vega:OTTHUMG00000164984 +4857 NOVA1 MIM:602157|HGNC:HGNC:7886|Ensembl:ENSG00000139910|Vega:OTTHUMG00000029385 +4858 NOVA2 MIM:601991|HGNC:HGNC:7887|Ensembl:ENSG00000104967|Vega:OTTHUMG00000177499 +4860 PNP MIM:164050|HGNC:HGNC:7892|Ensembl:ENSG00000198805|Vega:OTTHUMG00000029546 +4861 NPAS1 MIM:603346|HGNC:HGNC:7894|Ensembl:ENSG00000130751|Vega:OTTHUMG00000183440 +4862 NPAS2 MIM:603347|HGNC:HGNC:7895|Ensembl:ENSG00000170485|Vega:OTTHUMG00000130675 +4863 NPAT MIM:601448|HGNC:HGNC:7896|Ensembl:ENSG00000149308|Vega:OTTHUMG00000166385 +4864 NPC1 MIM:607623|HGNC:HGNC:7897|Ensembl:ENSG00000141458|Vega:OTTHUMG00000131873 +4867 NPHP1 MIM:607100|HGNC:HGNC:7905|Ensembl:ENSG00000144061|Vega:OTTHUMG00000131195 +4868 NPHS1 MIM:602716|HGNC:HGNC:7908|Ensembl:ENSG00000161270|Vega:OTTHUMG00000180689 +4869 NPM1 MIM:164040|HGNC:HGNC:7910|Ensembl:ENSG00000181163|Vega:OTTHUMG00000130465 +4870 NPM1P1 HGNC:HGNC:7911 +4871 NPM1P2 HGNC:HGNC:7922 +4872 NPM1P3 HGNC:HGNC:7923 +4874 NPM1P5 HGNC:HGNC:7925 +4875 NPM1P6 HGNC:HGNC:7926 +4877 NT3 HGNC:HGNC:8020 +4878 NPPA MIM:108780|HGNC:HGNC:7939|Ensembl:ENSG00000175206|Vega:OTTHUMG00000002388 +4879 NPPB MIM:600295|HGNC:HGNC:7940|Ensembl:ENSG00000120937|Vega:OTTHUMG00000002389 +4880 NPPC MIM:600296|HGNC:HGNC:7941|Ensembl:ENSG00000163273|Vega:OTTHUMG00000133232 +4881 NPR1 MIM:108960|HGNC:HGNC:7943|Ensembl:ENSG00000169418|Vega:OTTHUMG00000037085 +4882 NPR2 MIM:108961|HGNC:HGNC:7944|Ensembl:ENSG00000159899|Vega:OTTHUMG00000019871 +4883 NPR3 MIM:108962|HGNC:HGNC:7945|Ensembl:ENSG00000113389|Vega:OTTHUMG00000150316 +4884 NPTX1 MIM:602367|HGNC:HGNC:7952|Ensembl:ENSG00000171246|Vega:OTTHUMG00000177607 +4885 NPTX2 MIM:600750|HGNC:HGNC:7953|Ensembl:ENSG00000106236|Vega:OTTHUMG00000154369 +4886 NPY1R MIM:162641|HGNC:HGNC:7956|Ensembl:ENSG00000164128|Vega:OTTHUMG00000161371 +4887 NPY2R MIM:162642|HGNC:HGNC:7957|Ensembl:ENSG00000185149|Vega:OTTHUMG00000161485 +4888 NPY6R MIM:601770|HGNC:HGNC:7959|Ensembl:ENSG00000226306 +4889 NPY5R MIM:602001|HGNC:HGNC:7958|Ensembl:ENSG00000164129|Vega:OTTHUMG00000161353 +4891 SLC11A2 MIM:600523|HGNC:HGNC:10908|Ensembl:ENSG00000110911|Vega:OTTHUMG00000169493 +4892 NRAP MIM:602873|HGNC:HGNC:7988|Ensembl:ENSG00000197893|Vega:OTTHUMG00000019072 +4893 NRAS MIM:164790|HGNC:HGNC:7989|Ensembl:ENSG00000213281|Vega:OTTHUMG00000012059 +4897 NRCAM MIM:601581|HGNC:HGNC:7994|Ensembl:ENSG00000091129|Vega:OTTHUMG00000154973 +4898 NRDC MIM:602651|HGNC:HGNC:7995|Ensembl:ENSG00000078618|Vega:OTTHUMG00000008278 +4899 NRF1 MIM:600879|HGNC:HGNC:7996|Ensembl:ENSG00000106459|Vega:OTTHUMG00000143736 +4900 NRGN MIM:602350|HGNC:HGNC:8000|Ensembl:ENSG00000154146|Vega:OTTHUMG00000165928 +4901 NRL MIM:162080|HGNC:HGNC:8002|Ensembl:ENSG00000129535|Vega:OTTHUMG00000028789 +4902 NRTN MIM:602018|HGNC:HGNC:8007|Ensembl:ENSG00000171119|Vega:OTTHUMG00000180555 +4904 YBX1 MIM:154030|HGNC:HGNC:8014|Ensembl:ENSG00000065978|Vega:OTTHUMG00000007523 +4905 NSF MIM:601633|HGNC:HGNC:8016|Ensembl:ENSG00000073969|Vega:OTTHUMG00000134315 +4907 NT5E MIM:129190|HGNC:HGNC:8021|Ensembl:ENSG00000135318|Vega:OTTHUMG00000015139 +4908 NTF3 MIM:162660|HGNC:HGNC:8023|Ensembl:ENSG00000185652|Vega:OTTHUMG00000168649 +4909 NTF4 MIM:162662|HGNC:HGNC:8024|Ensembl:ENSG00000225950|Vega:OTTHUMG00000191728 +4910 NTF6A HGNC:HGNC:8025 +4911 NTF6B HGNC:HGNC:8026 +4912 NTF6G HGNC:HGNC:8027 +4913 NTHL1 MIM:602656|HGNC:HGNC:8028|Ensembl:ENSG00000065057|Vega:OTTHUMG00000128744 +4914 NTRK1 MIM:191315|HGNC:HGNC:8031|Ensembl:ENSG00000198400|Vega:OTTHUMG00000041304 +4915 NTRK2 MIM:600456|HGNC:HGNC:8032|Ensembl:ENSG00000148053|Vega:OTTHUMG00000020120 +4916 NTRK3 MIM:191316|HGNC:HGNC:8033|Ensembl:ENSG00000140538|Vega:OTTHUMG00000148677 +4917 NTN3 MIM:602349|HGNC:HGNC:8030|Ensembl:ENSG00000162068|Vega:OTTHUMG00000128867 +4919 ROR1 MIM:602336|HGNC:HGNC:10256|Ensembl:ENSG00000185483|Vega:OTTHUMG00000009022 +4920 ROR2 MIM:602337|HGNC:HGNC:10257|Ensembl:ENSG00000169071|Vega:OTTHUMG00000020211 +4921 DDR2 MIM:191311|HGNC:HGNC:2731|Ensembl:ENSG00000162733|Vega:OTTHUMG00000034423 +4922 NTS MIM:162650|HGNC:HGNC:8038|Ensembl:ENSG00000133636|Vega:OTTHUMG00000169832 +4923 NTSR1 MIM:162651|HGNC:HGNC:8039|Ensembl:ENSG00000101188|Vega:OTTHUMG00000032932 +4924 NUCB1 MIM:601323|HGNC:HGNC:8043|Ensembl:ENSG00000104805|Vega:OTTHUMG00000152514 +4925 NUCB2 MIM:608020|HGNC:HGNC:8044|Ensembl:ENSG00000070081|Vega:OTTHUMG00000166050 +4926 NUMA1 MIM:164009|HGNC:HGNC:8059|Ensembl:ENSG00000137497|Vega:OTTHUMG00000167697 +4927 NUP88 MIM:602552|HGNC:HGNC:8067|Ensembl:ENSG00000108559|Vega:OTTHUMG00000099453 +4928 NUP98 MIM:601021|HGNC:HGNC:8068|Ensembl:ENSG00000110713|Vega:OTTHUMG00000011846 +4929 NR4A2 MIM:601828|HGNC:HGNC:7981|Ensembl:ENSG00000153234|Vega:OTTHUMG00000131950 +4931 NVL MIM:602426|HGNC:HGNC:8070|Ensembl:ENSG00000143748|Vega:OTTHUMG00000037536 +4933 NYS2 MIM:164100|HGNC:HGNC:8080 +4934 NYS3 MIM:608345|HGNC:HGNC:8081 +4935 GPR143 MIM:300808|HGNC:HGNC:20145|Ensembl:ENSG00000101850|Vega:OTTHUMG00000021118 +4936 OA3 HGNC:HGNC:8084 +4937 OAP HGNC:HGNC:8085 +4938 OAS1 MIM:164350|HGNC:HGNC:8086|Ensembl:ENSG00000089127|Vega:OTTHUMG00000169792 +4939 OAS2 MIM:603350|HGNC:HGNC:8087|Ensembl:ENSG00000111335|Vega:OTTHUMG00000169802 +4940 OAS3 MIM:603351|HGNC:HGNC:8088|Ensembl:ENSG00000111331|Vega:OTTHUMG00000169795 +4941 OASD MIM:300650|HGNC:HGNC:8089 +4942 OAT MIM:613349|HGNC:HGNC:8091|Ensembl:ENSG00000065154|Vega:OTTHUMG00000019213 +4943 TBC1D25 MIM:311240|HGNC:HGNC:8092|Ensembl:ENSG00000068354|Vega:OTTHUMG00000024123 +4945 OATP1 HGNC:HGNC:8094 +4946 OAZ1 MIM:601579|HGNC:HGNC:8095|Ensembl:ENSG00000104904|Vega:OTTHUMG00000178459 +4947 OAZ2 MIM:604152|HGNC:HGNC:8096|Ensembl:ENSG00000180304|Vega:OTTHUMG00000172473 +4948 OCA2 MIM:611409|HGNC:HGNC:8101|Ensembl:ENSG00000104044|Vega:OTTHUMG00000128871 +4951 OCM2 HGNC:HGNC:34396|Ensembl:ENSG00000135175|Vega:OTTHUMG00000154162 +4952 OCRL MIM:300535|HGNC:HGNC:8108|Ensembl:ENSG00000122126|Vega:OTTHUMG00000022706 +4953 ODC1 MIM:165640|HGNC:HGNC:8109|Ensembl:ENSG00000115758|Vega:OTTHUMG00000090450 +4954 ODCP HGNC:HGNC:8110 +4956 ODF1 MIM:182878|HGNC:HGNC:8113|Ensembl:ENSG00000155087|Vega:OTTHUMG00000164719 +4957 ODF2 MIM:602015|HGNC:HGNC:8114|Ensembl:ENSG00000136811|Vega:OTTHUMG00000020748 +4958 OMD HGNC:HGNC:8134|Ensembl:ENSG00000127083|Vega:OTTHUMG00000020225 +4961 OED HGNC:HGNC:8118 +4963 OFC1 MIM:119530|HGNC:HGNC:8120 +4964 OFC2 MIM:602966|HGNC:HGNC:8121 +4965 OFC3 MIM:600757|HGNC:HGNC:8122 +4967 OGDH MIM:613022|HGNC:HGNC:8124|Ensembl:ENSG00000105953|Vega:OTTHUMG00000155304 +4968 OGG1 MIM:601982|HGNC:HGNC:8125|Ensembl:ENSG00000114026|Vega:OTTHUMG00000097091 +4969 OGN MIM:602383|HGNC:HGNC:8126|Ensembl:ENSG00000106809|Vega:OTTHUMG00000020224 +4973 OLR1 MIM:602601|HGNC:HGNC:8133|Ensembl:ENSG00000173391|Vega:OTTHUMG00000168527 +4974 OMG MIM:164345|HGNC:HGNC:8135|Ensembl:ENSG00000126861|Vega:OTTHUMG00000132870 +4975 OMP MIM:164340|HGNC:HGNC:8136|Ensembl:ENSG00000254550|Vega:OTTHUMG00000165193 +4976 OPA1 MIM:605290|HGNC:HGNC:8140|Ensembl:ENSG00000198836|Vega:OTTHUMG00000149897 +4977 OPA2 MIM:311050|HGNC:HGNC:8141 +4978 OPCML MIM:600632|HGNC:HGNC:8143|Ensembl:ENSG00000183715|Vega:OTTHUMG00000163658 +4981 OPEM MIM:311000|HGNC:HGNC:8146 +4982 TNFRSF11B MIM:602643|HGNC:HGNC:11909|Ensembl:ENSG00000164761|Vega:OTTHUMG00000164969 +4983 OPHN1 MIM:300127|HGNC:HGNC:8148|Ensembl:ENSG00000079482|Vega:OTTHUMG00000021744 +4985 OPRD1 MIM:165195|HGNC:HGNC:8153|Ensembl:ENSG00000116329|Vega:OTTHUMG00000003646 +4986 OPRK1 MIM:165196|HGNC:HGNC:8154|Ensembl:ENSG00000082556|Vega:OTTHUMG00000164276 +4987 OPRL1 MIM:602548|HGNC:HGNC:8155|Ensembl:ENSG00000125510|Vega:OTTHUMG00000033027 +4988 OPRM1 MIM:600018|HGNC:HGNC:8156|Ensembl:ENSG00000112038|Vega:OTTHUMG00000015870 +4990 SIX6 MIM:606326|HGNC:HGNC:10892|Ensembl:ENSG00000184302|Vega:OTTHUMG00000152339 +4991 OR1D2 MIM:164342|HGNC:HGNC:8183|Ensembl:ENSG00000184166|Vega:OTTHUMG00000090619 +4992 OR1F1 MIM:603232|HGNC:HGNC:8194|Ensembl:ENSG00000168124|Vega:OTTHUMG00000133153 +4993 OR2C1 HGNC:HGNC:8242|Ensembl:ENSG00000168158|Vega:OTTHUMG00000090505 +4994 OR3A1 HGNC:HGNC:8282|Ensembl:ENSG00000180090|Vega:OTTHUMG00000090642 +4995 OR3A2 HGNC:HGNC:8283|Ensembl:ENSG00000221882|Vega:OTTHUMG00000177667 +4998 ORC1 MIM:601902|HGNC:HGNC:8487|Ensembl:ENSG00000085840|Vega:OTTHUMG00000008104 +4999 ORC2 MIM:601182|HGNC:HGNC:8488|Ensembl:ENSG00000115942|Vega:OTTHUMG00000132783 +5000 ORC4 MIM:603056|HGNC:HGNC:8490|Ensembl:ENSG00000115947|Vega:OTTHUMG00000131849 +5001 ORC5 MIM:602331|HGNC:HGNC:8491|Ensembl:ENSG00000164815|Vega:OTTHUMG00000157275 +5002 SLC22A18 MIM:602631|HGNC:HGNC:10964|Ensembl:ENSG00000110628|Vega:OTTHUMG00000010037 +5003 SLC22A18AS MIM:603240|HGNC:HGNC:10965|Ensembl:ENSG00000254827|Vega:OTTHUMG00000010038 +5004 ORM1 MIM:138600|HGNC:HGNC:8498|Ensembl:ENSG00000229314|Vega:OTTHUMG00000021012 +5005 ORM2 MIM:138610|HGNC:HGNC:8499|Ensembl:ENSG00000228278|Vega:OTTHUMG00000021014 +5007 OSBP MIM:167040|HGNC:HGNC:8503|Ensembl:ENSG00000110048|Vega:OTTHUMG00000167422 +5008 OSM MIM:165095|HGNC:HGNC:8506|Ensembl:ENSG00000099985|Vega:OTTHUMG00000150913 +5009 OTC MIM:300461|HGNC:HGNC:8512|Ensembl:ENSG00000036473|Vega:OTTHUMG00000022727 +5010 CLDN11 MIM:601326|HGNC:HGNC:8514|Ensembl:ENSG00000013297|Vega:OTTHUMG00000158940 +5012 OTSC1 MIM:166800|HGNC:HGNC:8519 +5013 OTX1 MIM:600036|HGNC:HGNC:8521|Ensembl:ENSG00000115507|Vega:OTTHUMG00000129454 +5015 OTX2 MIM:600037|HGNC:HGNC:8522|Ensembl:ENSG00000165588|Vega:OTTHUMG00000152338 +5016 OVGP1 MIM:603578|HGNC:HGNC:8524|Ensembl:ENSG00000085465|Vega:OTTHUMG00000011746 +5017 OVOL1 MIM:602313|HGNC:HGNC:8525|Ensembl:ENSG00000172818|Vega:OTTHUMG00000166600 +5018 OXA1L MIM:601066|HGNC:HGNC:8526|Ensembl:ENSG00000155463|Vega:OTTHUMG00000028691 +5019 OXCT1 MIM:601424|HGNC:HGNC:8527|Ensembl:ENSG00000083720|Vega:OTTHUMG00000094783 +5020 OXT MIM:167050|HGNC:HGNC:8528|Ensembl:ENSG00000101405|Vega:OTTHUMG00000031724 +5021 OXTR MIM:167055|HGNC:HGNC:8529|Ensembl:ENSG00000180914|Vega:OTTHUMG00000090537 +5023 P2RX1 MIM:600845|HGNC:HGNC:8533|Ensembl:ENSG00000108405|Vega:OTTHUMG00000177673 +5024 P2RX3 MIM:600843|HGNC:HGNC:8534|Ensembl:ENSG00000109991|Vega:OTTHUMG00000167025 +5025 P2RX4 MIM:600846|HGNC:HGNC:8535|Ensembl:ENSG00000135124|Vega:OTTHUMG00000169155 +5026 P2RX5 MIM:602836|HGNC:HGNC:8536|Ensembl:ENSG00000083454|Vega:OTTHUMG00000090700 +5027 P2RX7 MIM:602566|HGNC:HGNC:8537|Ensembl:ENSG00000089041|Vega:OTTHUMG00000169153 +5028 P2RY1 MIM:601167|HGNC:HGNC:8539|Ensembl:ENSG00000169860|Vega:OTTHUMG00000159694 +5029 P2RY2 MIM:600041|HGNC:HGNC:8541|Ensembl:ENSG00000175591|Vega:OTTHUMG00000167966 +5030 P2RY4 MIM:300038|HGNC:HGNC:8542|Ensembl:ENSG00000186912|Vega:OTTHUMG00000021769 +5031 P2RY6 MIM:602451|HGNC:HGNC:8543|Ensembl:ENSG00000171631|Vega:OTTHUMG00000167969 +5032 P2RY11 MIM:602697|HGNC:HGNC:8540|Ensembl:ENSG00000244165|Vega:OTTHUMG00000150166 +5033 P4HA1 MIM:176710|HGNC:HGNC:8546|Ensembl:ENSG00000122884|Vega:OTTHUMG00000018449 +5034 P4HB MIM:176790|HGNC:HGNC:8548|Ensembl:ENSG00000185624|Vega:OTTHUMG00000150269 +5036 PA2G4 MIM:602145|HGNC:HGNC:8550|Ensembl:ENSG00000170515|Vega:OTTHUMG00000170173 +5037 PEBP1 MIM:604591|HGNC:HGNC:8630|Ensembl:ENSG00000089220|Vega:OTTHUMG00000168860 +5042 PABPC3 MIM:604680|HGNC:HGNC:8556|Ensembl:ENSG00000151846|Vega:OTTHUMG00000016601 +5043 PABX HGNC:HGNC:8566 +5044 PABY HGNC:HGNC:8567 +5045 FURIN MIM:136950|HGNC:HGNC:8568|Ensembl:ENSG00000140564|Vega:OTTHUMG00000149831 +5046 PCSK6 MIM:167405|HGNC:HGNC:8569|Ensembl:ENSG00000140479|Vega:OTTHUMG00000172097 +5047 PAEP MIM:173310|HGNC:HGNC:8573|Ensembl:ENSG00000122133|Vega:OTTHUMG00000020914 +5048 PAFAH1B1 MIM:601545|HGNC:HGNC:8574|Ensembl:ENSG00000007168|Vega:OTTHUMG00000177574 +5049 PAFAH1B2 MIM:602508|HGNC:HGNC:8575|Ensembl:ENSG00000168092|Vega:OTTHUMG00000167064 +5050 PAFAH1B3 MIM:603074|HGNC:HGNC:8576|Ensembl:ENSG00000079462|Vega:OTTHUMG00000182795 +5051 PAFAH2 MIM:602344|HGNC:HGNC:8579|Ensembl:ENSG00000158006|Vega:OTTHUMG00000007437 +5052 PRDX1 MIM:176763|HGNC:HGNC:9352|Ensembl:ENSG00000117450|Vega:OTTHUMG00000007738 +5053 PAH MIM:612349|HGNC:HGNC:8582|Ensembl:ENSG00000171759|Vega:OTTHUMG00000169966 +5054 SERPINE1 MIM:173360|HGNC:HGNC:8583|Ensembl:ENSG00000106366|Vega:OTTHUMG00000157107 +5055 SERPINB2 MIM:173390|HGNC:HGNC:8584|Ensembl:ENSG00000197632|Vega:OTTHUMG00000060592 +5058 PAK1 MIM:602590|HGNC:HGNC:8590|Ensembl:ENSG00000149269|Vega:OTTHUMG00000165138 +5062 PAK2 MIM:605022|HGNC:HGNC:8591|Ensembl:ENSG00000180370|Vega:OTTHUMG00000155534 +5063 PAK3 MIM:300142|HGNC:HGNC:8592|Ensembl:ENSG00000077264|Vega:OTTHUMG00000022202 +5064 PALM MIM:608134|HGNC:HGNC:8594|Ensembl:ENSG00000099864|Vega:OTTHUMG00000181785 +5066 PAM MIM:170270|HGNC:HGNC:8596|Ensembl:ENSG00000145730|Vega:OTTHUMG00000128729 +5067 CNTN3 MIM:601325|HGNC:HGNC:2173|Ensembl:ENSG00000113805|Vega:OTTHUMG00000158813 +5068 REG3A MIM:167805|HGNC:HGNC:8601|Ensembl:ENSG00000172016|Vega:OTTHUMG00000130017 +5069 PAPPA MIM:176385|HGNC:HGNC:8602|Ensembl:ENSG00000182752|Vega:OTTHUMG00000021045 +5071 PRKN MIM:602544|HGNC:HGNC:8607|Ensembl:ENSG00000185345|Vega:OTTHUMG00000015970 +5072 PARK3 MIM:602404|HGNC:HGNC:8608 +5073 PARN MIM:604212|HGNC:HGNC:8609|Ensembl:ENSG00000140694|Vega:OTTHUMG00000173199 +5074 PAWR MIM:601936|HGNC:HGNC:8614|Ensembl:ENSG00000177425|Vega:OTTHUMG00000170080 +5075 PAX1 MIM:167411|HGNC:HGNC:8615|Ensembl:ENSG00000125813|Vega:OTTHUMG00000032034 +5076 PAX2 MIM:167409|HGNC:HGNC:8616|Ensembl:ENSG00000075891|Vega:OTTHUMG00000018913 +5077 PAX3 MIM:606597|HGNC:HGNC:8617|Ensembl:ENSG00000135903|Vega:OTTHUMG00000133157 +5078 PAX4 MIM:167413|HGNC:HGNC:8618|Ensembl:ENSG00000106331|Vega:OTTHUMG00000157562 +5079 PAX5 MIM:167414|HGNC:HGNC:8619|Ensembl:ENSG00000196092|Vega:OTTHUMG00000019907 +5080 PAX6 MIM:607108|HGNC:HGNC:8620|Ensembl:ENSG00000007372|Vega:OTTHUMG00000041447 +5081 PAX7 MIM:167410|HGNC:HGNC:8621|Ensembl:ENSG00000009709|Vega:OTTHUMG00000002433 +5082 PDCL MIM:604421|HGNC:HGNC:8770|Ensembl:ENSG00000136940|Vega:OTTHUMG00000020624 +5083 PAX9 MIM:167416|HGNC:HGNC:8623|Ensembl:ENSG00000198807|Vega:OTTHUMG00000140251 +5084 PBG1 HGNC:HGNC:8627 +5087 PBX1 MIM:176310|HGNC:HGNC:8632|Ensembl:ENSG00000185630|Vega:OTTHUMG00000034307 +5088 PBX2P1 HGNC:HGNC:8635 +5089 PBX2 MIM:176311|HGNC:HGNC:8633|Ensembl:ENSG00000204304|Vega:OTTHUMG00000031116 +5090 PBX3 MIM:176312|HGNC:HGNC:8634|Ensembl:ENSG00000167081|Vega:OTTHUMG00000020684 +5091 PC MIM:608786|HGNC:HGNC:8636|Ensembl:ENSG00000173599|Vega:OTTHUMG00000167099 +5092 PCBD1 MIM:126090|HGNC:HGNC:8646|Ensembl:ENSG00000166228|Vega:OTTHUMG00000018417 +5093 PCBP1 MIM:601209|HGNC:HGNC:8647|Ensembl:ENSG00000169564|Vega:OTTHUMG00000129645 +5094 PCBP2 MIM:601210|HGNC:HGNC:8648|Ensembl:ENSG00000197111|Vega:OTTHUMG00000169439 +5095 PCCA MIM:232000|HGNC:HGNC:8653|Ensembl:ENSG00000175198|Vega:OTTHUMG00000017284 +5096 PCCB MIM:232050|HGNC:HGNC:8654|Ensembl:ENSG00000114054|Vega:OTTHUMG00000159792 +5097 PCDH1 MIM:603626|HGNC:HGNC:8655|Ensembl:ENSG00000156453|Vega:OTTHUMG00000129661 +5098 PCDHGC3 MIM:603627|HGNC:HGNC:8716|Ensembl:ENSG00000240184|Ensembl:ENSG00000242419|Vega:OTTHUMG00000129613|Vega:OTTHUMG00000129625 +5099 PCDH7 MIM:602988|HGNC:HGNC:8659|Ensembl:ENSG00000169851|Vega:OTTHUMG00000160364 +5100 PCDH8 MIM:603580|HGNC:HGNC:8660|Ensembl:ENSG00000136099|Vega:OTTHUMG00000016979 +5101 PCDH9 MIM:603581|HGNC:HGNC:8661|Ensembl:ENSG00000184226|Vega:OTTHUMG00000017040 +5104 SERPINA5 MIM:601841|HGNC:HGNC:8723|Ensembl:ENSG00000188488|Vega:OTTHUMG00000170860 +5105 PCK1 MIM:614168|HGNC:HGNC:8724|Ensembl:ENSG00000124253|Vega:OTTHUMG00000032825 +5106 PCK2 MIM:614095|HGNC:HGNC:8725|Ensembl:ENSG00000100889|Vega:OTTHUMG00000028791 +5108 PCM1 MIM:600299|HGNC:HGNC:8727|Ensembl:ENSG00000078674|Vega:OTTHUMG00000163699 +5110 PCMT1 MIM:176851|HGNC:HGNC:8728|Ensembl:ENSG00000120265|Vega:OTTHUMG00000015794 +5111 PCNA MIM:176740|HGNC:HGNC:8729|Ensembl:ENSG00000132646|Vega:OTTHUMG00000031798 +5116 PCNT MIM:605925|HGNC:HGNC:16068|Ensembl:ENSG00000160299|Vega:OTTHUMG00000090665 +5118 PCOLCE MIM:600270|HGNC:HGNC:8738|Ensembl:ENSG00000106333|Vega:OTTHUMG00000156675 +5119 CHMP1A MIM:164010|HGNC:HGNC:8740|Ensembl:ENSG00000131165|Vega:OTTHUMG00000169521 +5120 PCOS1 MIM:184700|HGNC:HGNC:8741 +5121 PCP4 MIM:601629|HGNC:HGNC:8742|Ensembl:ENSG00000183036|Vega:OTTHUMG00000086731 +5122 PCSK1 MIM:162150|HGNC:HGNC:8743|Ensembl:ENSG00000175426|Vega:OTTHUMG00000122089 +5125 PCSK5 MIM:600488|HGNC:HGNC:8747|Ensembl:ENSG00000099139|Vega:OTTHUMG00000020039 +5126 PCSK2 MIM:162151|HGNC:HGNC:8744|Ensembl:ENSG00000125851|Vega:OTTHUMG00000031941 +5127 CDK16 MIM:311550|HGNC:HGNC:8749|Ensembl:ENSG00000102225|Vega:OTTHUMG00000021438 +5128 CDK17 MIM:603440|HGNC:HGNC:8750|Ensembl:ENSG00000059758|Vega:OTTHUMG00000170375 +5129 CDK18 MIM:169190|HGNC:HGNC:8751|Ensembl:ENSG00000117266|Vega:OTTHUMG00000037203 +5130 PCYT1A MIM:123695|HGNC:HGNC:8754|Ensembl:ENSG00000161217|Vega:OTTHUMG00000155670 +5131 PDB1 MIM:167250|HGNC:HGNC:8757 +5132 PDC MIM:171490|HGNC:HGNC:8759|Ensembl:ENSG00000116703|Vega:OTTHUMG00000035575 +5133 PDCD1 MIM:600244|HGNC:HGNC:8760|Ensembl:ENSG00000188389|Vega:OTTHUMG00000151342 +5134 PDCD2 MIM:600866|HGNC:HGNC:8762|Ensembl:ENSG00000071994|Vega:OTTHUMG00000016083 +5136 PDE1A MIM:171890|HGNC:HGNC:8774|Ensembl:ENSG00000115252|Vega:OTTHUMG00000132596 +5137 PDE1C MIM:602987|HGNC:HGNC:8776|Ensembl:ENSG00000154678|Vega:OTTHUMG00000023836 +5138 PDE2A MIM:602658|HGNC:HGNC:8777|Ensembl:ENSG00000186642|Vega:OTTHUMG00000102045 +5139 PDE3A MIM:123805|HGNC:HGNC:8778|Ensembl:ENSG00000172572|Vega:OTTHUMG00000168962 +5140 PDE3B MIM:602047|HGNC:HGNC:8779|Ensembl:ENSG00000152270|Vega:OTTHUMG00000165898 +5141 PDE4A MIM:600126|HGNC:HGNC:8780|Ensembl:ENSG00000065989|Vega:OTTHUMG00000180411 +5142 PDE4B MIM:600127|HGNC:HGNC:8781|Ensembl:ENSG00000184588|Vega:OTTHUMG00000009088 +5143 PDE4C MIM:600128|HGNC:HGNC:8782|Ensembl:ENSG00000105650|Vega:OTTHUMG00000183353 +5144 PDE4D MIM:600129|HGNC:HGNC:8783|Ensembl:ENSG00000113448|Vega:OTTHUMG00000162218 +5145 PDE6A MIM:180071|HGNC:HGNC:8785|Ensembl:ENSG00000132915|Vega:OTTHUMG00000130047 +5146 PDE6C MIM:600827|HGNC:HGNC:8787|Ensembl:ENSG00000095464|Vega:OTTHUMG00000018775 +5147 PDE6D MIM:602676|HGNC:HGNC:8788|Ensembl:ENSG00000156973|Vega:OTTHUMG00000153785 +5148 PDE6G MIM:180073|HGNC:HGNC:8789|Ensembl:ENSG00000185527|Vega:OTTHUMG00000178038 +5149 PDE6H MIM:601190|HGNC:HGNC:8790|Ensembl:ENSG00000139053|Vega:OTTHUMG00000168743 +5150 PDE7A MIM:171885|HGNC:HGNC:8791|Ensembl:ENSG00000205268|Vega:OTTHUMG00000164469 +5151 PDE8A MIM:602972|HGNC:HGNC:8793|Ensembl:ENSG00000073417|Vega:OTTHUMG00000148670 +5152 PDE9A MIM:602973|HGNC:HGNC:8795|Ensembl:ENSG00000160191|Vega:OTTHUMG00000086825 +5153 PDE1B MIM:171891|HGNC:HGNC:8775|Ensembl:ENSG00000123360|Vega:OTTHUMG00000169844 +5154 PDGFA MIM:173430|HGNC:HGNC:8799|Ensembl:ENSG00000197461|Vega:OTTHUMG00000151412 +5155 PDGFB MIM:190040|HGNC:HGNC:8800|Ensembl:ENSG00000100311|Vega:OTTHUMG00000151029 +5156 PDGFRA MIM:173490|HGNC:HGNC:8803|Ensembl:ENSG00000134853|Vega:OTTHUMG00000128699 +5157 PDGFRL MIM:604584|HGNC:HGNC:8805|Ensembl:ENSG00000104213|Vega:OTTHUMG00000130818 +5158 PDE6B MIM:180072|HGNC:HGNC:8786|Ensembl:ENSG00000133256|Vega:OTTHUMG00000159909 +5159 PDGFRB MIM:173410|HGNC:HGNC:8804|Ensembl:ENSG00000113721|Vega:OTTHUMG00000130053 +5160 PDHA1 MIM:300502|HGNC:HGNC:8806|Ensembl:ENSG00000131828|Vega:OTTHUMG00000021224 +5161 PDHA2 MIM:179061|HGNC:HGNC:8807|Ensembl:ENSG00000163114|Vega:OTTHUMG00000130990 +5162 PDHB MIM:179060|HGNC:HGNC:8808|Ensembl:ENSG00000168291|Vega:OTTHUMG00000159157 +5163 PDK1 MIM:602524|HGNC:HGNC:8809|Ensembl:ENSG00000152256|Vega:OTTHUMG00000132285 +5164 PDK2 MIM:602525|HGNC:HGNC:8810|Ensembl:ENSG00000005882|Vega:OTTHUMG00000161948 +5165 PDK3 MIM:300906|HGNC:HGNC:8811|Ensembl:ENSG00000067992|Vega:OTTHUMG00000021269 +5166 PDK4 MIM:602527|HGNC:HGNC:8812|Ensembl:ENSG00000004799|Vega:OTTHUMG00000153977 +5167 ENPP1 MIM:173335|HGNC:HGNC:3356|Ensembl:ENSG00000197594|Vega:OTTHUMG00000015572 +5168 ENPP2 MIM:601060|HGNC:HGNC:3357|Ensembl:ENSG00000136960|Vega:OTTHUMG00000164995 +5169 ENPP3 MIM:602182|HGNC:HGNC:3358|Ensembl:ENSG00000154269|Vega:OTTHUMG00000016292 +5170 PDPK1 MIM:605213|HGNC:HGNC:8816|Ensembl:ENSG00000140992|Vega:OTTHUMG00000128874 +5171 PDR MIM:301220|HGNC:HGNC:8817 +5172 SLC26A4 MIM:605646|HGNC:HGNC:8818|Ensembl:ENSG00000091137|Vega:OTTHUMG00000154807 +5173 PDYN MIM:131340|HGNC:HGNC:8820|Ensembl:ENSG00000101327|Vega:OTTHUMG00000031683 +5174 PDZK1 MIM:603831|HGNC:HGNC:8821|Ensembl:ENSG00000174827|Vega:OTTHUMG00000013735 +5175 PECAM1 MIM:173445|HGNC:HGNC:8823|Ensembl:ENSG00000261371|Vega:OTTHUMG00000175829 +5176 SERPINF1 MIM:172860|HGNC:HGNC:8824|Ensembl:ENSG00000132386|Vega:OTTHUMG00000090571 +5177 PEE1 MIM:189800|HGNC:HGNC:8825 +5178 PEG3 MIM:601483|HGNC:HGNC:8826|Ensembl:ENSG00000198300|Vega:OTTHUMG00000171954 +5179 PENK MIM:131330|HGNC:HGNC:8831|Ensembl:ENSG00000181195|Vega:OTTHUMG00000164409 +5182 PEPB MIM:169900|HGNC:HGNC:8838 +5183 PEPC MIM:170000|HGNC:HGNC:8839 +5184 PEPD MIM:613230|HGNC:HGNC:8840|Ensembl:ENSG00000124299|Vega:OTTHUMG00000180470 +5185 PEPE MIM:170200|HGNC:HGNC:8841 +5187 PER1 MIM:602260|HGNC:HGNC:8845|Ensembl:ENSG00000179094|Vega:OTTHUMG00000178317 +5188 GATB MIM:603645|HGNC:HGNC:8849|Ensembl:ENSG00000059691|Vega:OTTHUMG00000161672 +5189 PEX1 MIM:602136|HGNC:HGNC:8850|Ensembl:ENSG00000127980|Vega:OTTHUMG00000023926 +5190 PEX6 MIM:601498|HGNC:HGNC:8859|Ensembl:ENSG00000124587|Vega:OTTHUMG00000014713 +5191 PEX7 MIM:601757|HGNC:HGNC:8860|Ensembl:ENSG00000112357|Vega:OTTHUMG00000015650 +5192 PEX10 MIM:602859|HGNC:HGNC:8851|Ensembl:ENSG00000157911|Vega:OTTHUMG00000001637 +5193 PEX12 MIM:601758|HGNC:HGNC:8854|Ensembl:ENSG00000108733|Vega:OTTHUMG00000132951 +5194 PEX13 MIM:601789|HGNC:HGNC:8855|Ensembl:ENSG00000162928|Vega:OTTHUMG00000129422 +5195 PEX14 MIM:601791|HGNC:HGNC:8856|Ensembl:ENSG00000142655|Vega:OTTHUMG00000001908 +5196 PF4 MIM:173460|HGNC:HGNC:8861|Ensembl:ENSG00000163737|Vega:OTTHUMG00000130009 +5197 PF4V1 MIM:173461|HGNC:HGNC:8862|Ensembl:ENSG00000109272|Vega:OTTHUMG00000130177 +5198 PFAS MIM:602133|HGNC:HGNC:8863|Ensembl:ENSG00000178921|Vega:OTTHUMG00000108188 +5199 CFP MIM:300383|HGNC:HGNC:8864|Ensembl:ENSG00000126759|Vega:OTTHUMG00000021451 +5201 PFDN1 MIM:604897|HGNC:HGNC:8866|Ensembl:ENSG00000113068|Vega:OTTHUMG00000129249 +5202 PFDN2 MIM:613466|HGNC:HGNC:8867|Ensembl:ENSG00000143256|Vega:OTTHUMG00000031481 +5203 PFDN4 MIM:604898|HGNC:HGNC:8868|Ensembl:ENSG00000101132|Vega:OTTHUMG00000032775 +5204 PFDN5 MIM:604899|HGNC:HGNC:8869|Ensembl:ENSG00000123349|Vega:OTTHUMG00000169675 +5205 ATP8B1 MIM:602397|HGNC:HGNC:3706|Ensembl:ENSG00000081923|Vega:OTTHUMG00000180255 +5207 PFKFB1 MIM:311790|HGNC:HGNC:8872|Ensembl:ENSG00000158571|Vega:OTTHUMG00000021643 +5208 PFKFB2 MIM:171835|HGNC:HGNC:8873|Ensembl:ENSG00000123836|Vega:OTTHUMG00000036033 +5209 PFKFB3 MIM:605319|HGNC:HGNC:8874|Ensembl:ENSG00000170525|Vega:OTTHUMG00000017621 +5210 PFKFB4 MIM:605320|HGNC:HGNC:8875|Ensembl:ENSG00000114268|Vega:OTTHUMG00000133528 +5211 PFKL MIM:171860|HGNC:HGNC:8876|Ensembl:ENSG00000141959|Vega:OTTHUMG00000086910 +5212 VIT HGNC:HGNC:12697|Ensembl:ENSG00000205221|Vega:OTTHUMG00000152149 +5213 PFKM MIM:610681|HGNC:HGNC:8877|Ensembl:ENSG00000152556|Vega:OTTHUMG00000169898 +5214 PFKP MIM:171840|HGNC:HGNC:8878|Ensembl:ENSG00000067057|Vega:OTTHUMG00000017556 +5216 PFN1 MIM:176610|HGNC:HGNC:8881|Ensembl:ENSG00000108518|Vega:OTTHUMG00000099396 +5217 PFN2 MIM:176590|HGNC:HGNC:8882|Ensembl:ENSG00000070087|Vega:OTTHUMG00000159683 +5218 CDK14 MIM:610679|HGNC:HGNC:8883|Ensembl:ENSG00000058091|Vega:OTTHUMG00000023649 +5222 PGA5 MIM:169730|HGNC:HGNC:8887|Ensembl:ENSG00000256713|Vega:OTTHUMG00000168075 +5223 PGAM1 MIM:172250|HGNC:HGNC:8888|Ensembl:ENSG00000171314|Vega:OTTHUMG00000018846 +5224 PGAM2 MIM:612931|HGNC:HGNC:8889|Ensembl:ENSG00000164708|Vega:OTTHUMG00000155355 +5225 PGC MIM:169740|HGNC:HGNC:8890|Ensembl:ENSG00000096088|Vega:OTTHUMG00000014683 +5226 PGD MIM:172200|HGNC:HGNC:8891|Ensembl:ENSG00000142657|Vega:OTTHUMG00000001905 +5228 PGF MIM:601121|HGNC:HGNC:8893|Ensembl:ENSG00000119630|Vega:OTTHUMG00000171496 +5229 PGGT1B MIM:602031|HGNC:HGNC:8895|Ensembl:ENSG00000164219|Vega:OTTHUMG00000128893 +5230 PGK1 MIM:311800|HGNC:HGNC:8896|Ensembl:ENSG00000102144|Vega:OTTHUMG00000021888 +5231 PGK1P1 HGNC:HGNC:8897 +5232 PGK2 MIM:172270|HGNC:HGNC:8898|Ensembl:ENSG00000170950|Vega:OTTHUMG00000014824 +5233 PGK1P2 HGNC:HGNC:8899 +5236 PGM1 MIM:171900|HGNC:HGNC:8905|Ensembl:ENSG00000079739|Vega:OTTHUMG00000008968 +5238 PGM3 MIM:172100|HGNC:HGNC:8907|Ensembl:ENSG00000013375|Vega:OTTHUMG00000015110 +5239 PGM5 MIM:600981|HGNC:HGNC:8908|Ensembl:ENSG00000154330|Vega:OTTHUMG00000019966 +5241 PGR MIM:607311|HGNC:HGNC:8910|Ensembl:ENSG00000082175|Vega:OTTHUMG00000167531 +5243 ABCB1 MIM:171050|HGNC:HGNC:40|Ensembl:ENSG00000085563|Vega:OTTHUMG00000023393 +5244 ABCB4 MIM:171060|HGNC:HGNC:45|Ensembl:ENSG00000005471|Vega:OTTHUMG00000023396 +5245 PHB MIM:176705|HGNC:HGNC:8912|Ensembl:ENSG00000167085|Vega:OTTHUMG00000134271 +5246 PHBP1 HGNC:HGNC:8913 +5250 SLC25A3 MIM:600370|HGNC:HGNC:10989|Ensembl:ENSG00000075415|Vega:OTTHUMG00000170212 +5251 PHEX MIM:300550|HGNC:HGNC:8918|Ensembl:ENSG00000102174|Vega:OTTHUMG00000021241 +5252 PHF1 MIM:602881|HGNC:HGNC:8919|Ensembl:ENSG00000112511|Vega:OTTHUMG00000031105 +5253 PHF2 MIM:604351|HGNC:HGNC:8920|Ensembl:ENSG00000197724|Vega:OTTHUMG00000020253 +5255 PHKA1 MIM:311870|HGNC:HGNC:8925|Ensembl:ENSG00000067177|Vega:OTTHUMG00000022696 +5256 PHKA2 MIM:300798|HGNC:HGNC:8926|Ensembl:ENSG00000044446|Vega:OTTHUMG00000021222 +5257 PHKB MIM:172490|HGNC:HGNC:8927|Ensembl:ENSG00000102893|Vega:OTTHUMG00000133102 +5258 PHKBP1 HGNC:HGNC:8928 +5259 PHKBP2 HGNC:HGNC:8929 +5260 PHKG1 MIM:172470|HGNC:HGNC:8930|Ensembl:ENSG00000164776|Vega:OTTHUMG00000023869 +5261 PHKG2 MIM:172471|HGNC:HGNC:8931|Ensembl:ENSG00000156873|Vega:OTTHUMG00000132400 +5262 PHKG1P3 HGNC:HGNC:8932 +5264 PHYH MIM:602026|HGNC:HGNC:8940|Ensembl:ENSG00000107537|Vega:OTTHUMG00000017693 +5265 SERPINA1 MIM:107400|HGNC:HGNC:8941|Ensembl:ENSG00000197249|Vega:OTTHUMG00000150355 +5266 PI3 MIM:182257|HGNC:HGNC:8947|Ensembl:ENSG00000124102|Vega:OTTHUMG00000032567 +5267 SERPINA4 MIM:147935|HGNC:HGNC:8948|Ensembl:ENSG00000100665|Vega:OTTHUMG00000170859 +5268 SERPINB5 MIM:154790|HGNC:HGNC:8949|Ensembl:ENSG00000206075|Vega:OTTHUMG00000141307 +5269 SERPINB6 MIM:173321|HGNC:HGNC:8950|Ensembl:ENSG00000124570|Vega:OTTHUMG00000016170 +5270 SERPINE2 MIM:177010|HGNC:HGNC:8951|Ensembl:ENSG00000135919|Vega:OTTHUMG00000133163 +5271 SERPINB8 MIM:601697|HGNC:HGNC:8952|Ensembl:ENSG00000166401|Vega:OTTHUMG00000060596 +5272 SERPINB9 MIM:601799|HGNC:HGNC:8955|Ensembl:ENSG00000170542|Vega:OTTHUMG00000014131 +5273 SERPINB10 MIM:602058|HGNC:HGNC:8942|Ensembl:ENSG00000242550|Vega:OTTHUMG00000060594 +5274 SERPINI1 MIM:602445|HGNC:HGNC:8943|Ensembl:ENSG00000163536|Vega:OTTHUMG00000158450 +5275 SERPINB13 MIM:604445|HGNC:HGNC:8944|Ensembl:ENSG00000197641|Vega:OTTHUMG00000060406 +5276 SERPINI2 MIM:605587|HGNC:HGNC:8945|Ensembl:ENSG00000114204|Vega:OTTHUMG00000158231 +5277 PIGA MIM:311770|HGNC:HGNC:8957|Ensembl:ENSG00000165195|Vega:OTTHUMG00000021174 +5278 PIGAP1 HGNC:HGNC:8958 +5279 PIGC MIM:601730|HGNC:HGNC:8960|Ensembl:ENSG00000135845|Vega:OTTHUMG00000034751 +5280 PIGCP1 HGNC:HGNC:8961 +5281 PIGF MIM:600153|HGNC:HGNC:8962|Ensembl:ENSG00000151665|Vega:OTTHUMG00000128816 +5282 PIGFP1 HGNC:HGNC:8963 +5283 PIGH MIM:600154|HGNC:HGNC:8964|Ensembl:ENSG00000100564|Vega:OTTHUMG00000171806 +5284 PIGR MIM:173880|HGNC:HGNC:8968|Ensembl:ENSG00000162896|Vega:OTTHUMG00000036581 +5286 PIK3C2A MIM:603601|HGNC:HGNC:8971|Ensembl:ENSG00000011405|Vega:OTTHUMG00000166036 +5287 PIK3C2B MIM:602838|HGNC:HGNC:8972|Ensembl:ENSG00000133056|Vega:OTTHUMG00000036101 +5288 PIK3C2G MIM:609001|HGNC:HGNC:8973|Ensembl:ENSG00000139144|Vega:OTTHUMG00000168841 +5289 PIK3C3 MIM:602609|HGNC:HGNC:8974|Ensembl:ENSG00000078142|Vega:OTTHUMG00000132593 +5290 PIK3CA MIM:171834|HGNC:HGNC:8975|Ensembl:ENSG00000121879|Vega:OTTHUMG00000157311 +5291 PIK3CB MIM:602925|HGNC:HGNC:8976|Ensembl:ENSG00000051382|Vega:OTTHUMG00000159893 +5292 PIM1 MIM:164960|HGNC:HGNC:8986|Ensembl:ENSG00000137193|Vega:OTTHUMG00000016426 +5293 PIK3CD MIM:602839|HGNC:HGNC:8977|Ensembl:ENSG00000171608|Vega:OTTHUMG00000001450 +5294 PIK3CG MIM:601232|HGNC:HGNC:8978|Ensembl:ENSG00000105851|Vega:OTTHUMG00000157641 +5295 PIK3R1 MIM:171833|HGNC:HGNC:8979|Ensembl:ENSG00000145675|Vega:OTTHUMG00000131251 +5296 PIK3R2 MIM:603157|HGNC:HGNC:8980|Ensembl:ENSG00000105647|Ensembl:ENSG00000268173|Vega:OTTHUMG00000150640|Vega:OTTHUMG00000183383 +5297 PI4KA MIM:600286|HGNC:HGNC:8983|Ensembl:ENSG00000241973|Vega:OTTHUMG00000167440 +5298 PI4KB MIM:602758|HGNC:HGNC:8984|Ensembl:ENSG00000143393|Vega:OTTHUMG00000012348 +5300 PIN1 MIM:601052|HGNC:HGNC:8988|Ensembl:ENSG00000127445|Vega:OTTHUMG00000180388 +5301 PIN1P1 MIM:602051|HGNC:HGNC:8989|Ensembl:ENSG00000229359 +5303 PIN4 MIM:300252|HGNC:HGNC:8992|Ensembl:ENSG00000102309|Vega:OTTHUMG00000021811 +5304 PIP MIM:176720|HGNC:HGNC:8993|Ensembl:ENSG00000159763|Vega:OTTHUMG00000152635 +5305 PIP4K2A MIM:603140|HGNC:HGNC:8997|Ensembl:ENSG00000150867|Vega:OTTHUMG00000017810 +5306 PITPNA MIM:600174|HGNC:HGNC:9001|Ensembl:ENSG00000174238|Vega:OTTHUMG00000177779 +5307 PITX1 MIM:602149|HGNC:HGNC:9004|Ensembl:ENSG00000069011|Vega:OTTHUMG00000149983 +5308 PITX2 MIM:601542|HGNC:HGNC:9005|Ensembl:ENSG00000164093|Vega:OTTHUMG00000132837 +5309 PITX3 MIM:602669|HGNC:HGNC:9006|Ensembl:ENSG00000107859|Vega:OTTHUMG00000018952 +5310 PKD1 MIM:601313|HGNC:HGNC:9008|Ensembl:ENSG00000008710|Vega:OTTHUMG00000155795 +5311 PKD2 MIM:173910|HGNC:HGNC:9009|Ensembl:ENSG00000118762|Vega:OTTHUMG00000160982 +5312 PKD3 MIM:600666|HGNC:HGNC:9013 +5313 PKLR MIM:609712|HGNC:HGNC:9020|Ensembl:ENSG00000143627|Vega:OTTHUMG00000035875 +5314 PKHD1 MIM:606702|HGNC:HGNC:9016|Ensembl:ENSG00000170927|Vega:OTTHUMG00000014841 +5315 PKM MIM:179050|HGNC:HGNC:9021|Ensembl:ENSG00000067225|Vega:OTTHUMG00000172709 +5316 PKNOX1 MIM:602100|HGNC:HGNC:9022|Ensembl:ENSG00000160199|Vega:OTTHUMG00000086833 +5317 PKP1 MIM:601975|HGNC:HGNC:9023|Ensembl:ENSG00000081277|Vega:OTTHUMG00000035729 +5318 PKP2 MIM:602861|HGNC:HGNC:9024|Ensembl:ENSG00000057294|Vega:OTTHUMG00000169500 +5319 PLA2G1B MIM:172410|HGNC:HGNC:9030|Ensembl:ENSG00000170890|Vega:OTTHUMG00000169343 +5320 PLA2G2A MIM:172411|HGNC:HGNC:9031|Ensembl:ENSG00000188257|Vega:OTTHUMG00000002699 +5321 PLA2G4A MIM:600522|HGNC:HGNC:9035|Ensembl:ENSG00000116711|Vega:OTTHUMG00000035512 +5322 PLA2G5 MIM:601192|HGNC:HGNC:9038|Ensembl:ENSG00000127472|Vega:OTTHUMG00000002698 +5324 PLAG1 MIM:603026|HGNC:HGNC:9045|Ensembl:ENSG00000181690|Vega:OTTHUMG00000164310 +5325 PLAGL1 MIM:603044|HGNC:HGNC:9046|Ensembl:ENSG00000118495|Vega:OTTHUMG00000015738 +5326 PLAGL2 MIM:604866|HGNC:HGNC:9047|Ensembl:ENSG00000126003|Vega:OTTHUMG00000032210 +5327 PLAT MIM:173370|HGNC:HGNC:9051|Ensembl:ENSG00000104368|Vega:OTTHUMG00000164072 +5328 PLAU MIM:191840|HGNC:HGNC:9052|Ensembl:ENSG00000122861|Vega:OTTHUMG00000018494 +5329 PLAUR MIM:173391|HGNC:HGNC:9053|Ensembl:ENSG00000011422|Vega:OTTHUMG00000182778 +5330 PLCB2 MIM:604114|HGNC:HGNC:9055|Ensembl:ENSG00000137841|Vega:OTTHUMG00000172412 +5331 PLCB3 MIM:600230|HGNC:HGNC:9056|Ensembl:ENSG00000149782|Vega:OTTHUMG00000167816 +5332 PLCB4 MIM:600810|HGNC:HGNC:9059|Ensembl:ENSG00000101333|Vega:OTTHUMG00000031853 +5333 PLCD1 MIM:602142|HGNC:HGNC:9060|Ensembl:ENSG00000187091|Vega:OTTHUMG00000130813 +5334 PLCL1 MIM:600597|HGNC:HGNC:9063|Ensembl:ENSG00000115896|Vega:OTTHUMG00000132750 +5335 PLCG1 MIM:172420|HGNC:HGNC:9065|Ensembl:ENSG00000124181|Vega:OTTHUMG00000033082 +5336 PLCG2 MIM:600220|HGNC:HGNC:9066|Ensembl:ENSG00000197943|Vega:OTTHUMG00000176532 +5337 PLD1 MIM:602382|HGNC:HGNC:9067|Ensembl:ENSG00000075651|Vega:OTTHUMG00000156947 +5338 PLD2 MIM:602384|HGNC:HGNC:9068|Ensembl:ENSG00000129219|Vega:OTTHUMG00000090779 +5339 PLEC MIM:601282|HGNC:HGNC:9069|Ensembl:ENSG00000178209|Vega:OTTHUMG00000165291 +5340 PLG MIM:173350|HGNC:HGNC:9071|Ensembl:ENSG00000122194|Vega:OTTHUMG00000015957 +5341 PLEK MIM:173570|HGNC:HGNC:9070|Ensembl:ENSG00000115956|Vega:OTTHUMG00000129562 +5342 PLGLB2 HGNC:HGNC:9073|Ensembl:ENSG00000125551|Vega:OTTHUMG00000153273 +5343 PLGLB1 MIM:173340|HGNC:HGNC:9072|Ensembl:ENSG00000183281|Vega:OTTHUMG00000154612 +5345 SERPINF2 MIM:613168|HGNC:HGNC:9075|Ensembl:ENSG00000167711|Vega:OTTHUMG00000090552 +5346 PLIN1 MIM:170290|HGNC:HGNC:9076|Ensembl:ENSG00000166819|Vega:OTTHUMG00000149813 +5347 PLK1 MIM:602098|HGNC:HGNC:9077|Ensembl:ENSG00000166851|Vega:OTTHUMG00000096984 +5348 FXYD1 MIM:602359|HGNC:HGNC:4025|Ensembl:ENSG00000266964|Vega:OTTHUMG00000182359 +5349 FXYD3 MIM:604996|HGNC:HGNC:4027|Ensembl:ENSG00000089356|Vega:OTTHUMG00000184625 +5350 PLN MIM:172405|HGNC:HGNC:9080|Ensembl:ENSG00000198523|Vega:OTTHUMG00000015462 +5351 PLOD1 MIM:153454|HGNC:HGNC:9081|Ensembl:ENSG00000083444|Vega:OTTHUMG00000002393 +5352 PLOD2 MIM:601865|HGNC:HGNC:9082|Ensembl:ENSG00000152952|Vega:OTTHUMG00000159417 +5354 PLP1 MIM:300401|HGNC:HGNC:9086|Ensembl:ENSG00000123560|Vega:OTTHUMG00000022111 +5355 PLP2 MIM:300112|HGNC:HGNC:9087|Ensembl:ENSG00000102007|Vega:OTTHUMG00000021513 +5356 PLRG1 MIM:605961|HGNC:HGNC:9089|Ensembl:ENSG00000171566|Vega:OTTHUMG00000161411 +5357 PLS1 MIM:602734|HGNC:HGNC:9090|Ensembl:ENSG00000120756|Vega:OTTHUMG00000159292 +5358 PLS3 MIM:300131|HGNC:HGNC:9091|Ensembl:ENSG00000102024|Vega:OTTHUMG00000022237 +5359 PLSCR1 MIM:604170|HGNC:HGNC:9092|Ensembl:ENSG00000188313|Vega:OTTHUMG00000159427 +5360 PLTP MIM:172425|HGNC:HGNC:9093|Ensembl:ENSG00000100979|Vega:OTTHUMG00000033047 +5361 PLXNA1 MIM:601055|HGNC:HGNC:9099|Ensembl:ENSG00000114554|Vega:OTTHUMG00000044222 +5362 PLXNA2 MIM:601054|HGNC:HGNC:9100|Ensembl:ENSG00000076356|Vega:OTTHUMG00000036564 +5364 PLXNB1 MIM:601053|HGNC:HGNC:9103|Ensembl:ENSG00000164050|Vega:OTTHUMG00000133527 +5365 PLXNB3 MIM:300214|HGNC:HGNC:9105|Ensembl:ENSG00000198753|Vega:OTTHUMG00000024217 +5366 PMAIP1 MIM:604959|HGNC:HGNC:9108|Ensembl:ENSG00000141682|Vega:OTTHUMG00000132765 +5367 PMCH MIM:176795|HGNC:HGNC:9109|Ensembl:ENSG00000183395|Vega:OTTHUMG00000170479 +5368 PNOC MIM:601459|HGNC:HGNC:9163|Ensembl:ENSG00000168081|Vega:OTTHUMG00000102125 +5369 PMCHL1 MIM:176793|HGNC:HGNC:9110|Ensembl:ENSG00000168967 +5370 PMCHL2 MIM:176794|HGNC:HGNC:9111|Ensembl:ENSG00000169040 +5371 PML MIM:102578|HGNC:HGNC:9113|Ensembl:ENSG00000140464|Vega:OTTHUMG00000137607 +5372 PMM1 MIM:601786|HGNC:HGNC:9114|Ensembl:ENSG00000100417|Vega:OTTHUMG00000150972 +5373 PMM2 MIM:601785|HGNC:HGNC:9115|Ensembl:ENSG00000140650|Vega:OTTHUMG00000129697 +5375 PMP2 MIM:170715|HGNC:HGNC:9117|Ensembl:ENSG00000147588|Vega:OTTHUMG00000164600 +5376 PMP22 MIM:601097|HGNC:HGNC:9118|Ensembl:ENSG00000109099|Vega:OTTHUMG00000058960 +5378 PMS1 MIM:600258|HGNC:HGNC:9121|Ensembl:ENSG00000064933|Vega:OTTHUMG00000132664 +5379 PMS2P1 MIM:605038|HGNC:HGNC:9123 +5380 PMS2P2 HGNC:HGNC:9127 +5382 PMS2P4 HGNC:HGNC:9129 +5383 PMS2P5 HGNC:HGNC:9130 +5387 PMS2P3 HGNC:HGNC:9128|Ensembl:ENSG00000127957 +5393 EXOSC9 MIM:606180|HGNC:HGNC:9137|Ensembl:ENSG00000123737|Vega:OTTHUMG00000128783 +5394 EXOSC10 MIM:605960|HGNC:HGNC:9138|Ensembl:ENSG00000171824|Vega:OTTHUMG00000002123 +5395 PMS2 MIM:600259|HGNC:HGNC:9122|Ensembl:ENSG00000122512|Vega:OTTHUMG00000023135 +5396 PRRX1 MIM:167420|HGNC:HGNC:9142|Ensembl:ENSG00000116132|Vega:OTTHUMG00000035231 +5406 PNLIP MIM:246600|HGNC:HGNC:9155|Ensembl:ENSG00000175535|Vega:OTTHUMG00000019103 +5407 PNLIPRP1 MIM:604422|HGNC:HGNC:9156|Ensembl:ENSG00000187021|Vega:OTTHUMG00000019109 +5408 PNLIPRP2 MIM:604423|HGNC:HGNC:9157|Ensembl:ENSG00000266200|Vega:OTTHUMG00000181599 +5409 PNMT MIM:171190|HGNC:HGNC:9160|Ensembl:ENSG00000141744|Vega:OTTHUMG00000133209 +5411 PNN MIM:603154|HGNC:HGNC:9162|Ensembl:ENSG00000100941|Vega:OTTHUMG00000028821 +5412 UBL3 MIM:604711|HGNC:HGNC:12504|Ensembl:ENSG00000122042|Vega:OTTHUMG00000016661 +5413 SEPT5 MIM:602724|HGNC:HGNC:9164|Ensembl:ENSG00000184702|Vega:OTTHUMG00000150399 +5414 SEPT4 MIM:603696|HGNC:HGNC:9165|Ensembl:ENSG00000108387|Vega:OTTHUMG00000179243 +5420 PODXL MIM:602632|HGNC:HGNC:9171|Ensembl:ENSG00000128567|Vega:OTTHUMG00000154918 +5422 POLA1 MIM:312040|HGNC:HGNC:9173|Ensembl:ENSG00000101868|Vega:OTTHUMG00000021277 +5423 POLB MIM:174760|HGNC:HGNC:9174|Ensembl:ENSG00000070501|Vega:OTTHUMG00000164093 +5424 POLD1 MIM:174761|HGNC:HGNC:9175|Ensembl:ENSG00000062822|Vega:OTTHUMG00000183037 +5425 POLD2 MIM:600815|HGNC:HGNC:9176|Ensembl:ENSG00000106628|Vega:OTTHUMG00000022909 +5426 POLE MIM:174762|HGNC:HGNC:9177|Ensembl:ENSG00000177084|Vega:OTTHUMG00000168045 +5427 POLE2 MIM:602670|HGNC:HGNC:9178|Ensembl:ENSG00000100479|Vega:OTTHUMG00000170813 +5428 POLG MIM:174763|HGNC:HGNC:9179|Ensembl:ENSG00000140521|Vega:OTTHUMG00000149646 +5429 POLH MIM:603968|HGNC:HGNC:9181|Ensembl:ENSG00000170734|Vega:OTTHUMG00000014743 +5430 POLR2A MIM:180660|HGNC:HGNC:9187|Ensembl:ENSG00000181222|Vega:OTTHUMG00000177594 +5431 POLR2B MIM:180661|HGNC:HGNC:9188|Ensembl:ENSG00000047315|Vega:OTTHUMG00000128771 +5432 POLR2C MIM:180663|HGNC:HGNC:9189|Ensembl:ENSG00000102978|Vega:OTTHUMG00000133464 +5433 POLR2D MIM:606017|HGNC:HGNC:9191|Ensembl:ENSG00000144231|Vega:OTTHUMG00000131531 +5434 POLR2E MIM:180664|HGNC:HGNC:9192|Ensembl:ENSG00000099817|Vega:OTTHUMG00000181873 +5435 POLR2F MIM:604414|HGNC:HGNC:9193|Ensembl:ENSG00000100142|Vega:OTTHUMG00000151160 +5436 POLR2G MIM:602013|HGNC:HGNC:9194|Ensembl:ENSG00000168002|Vega:OTTHUMG00000167609 +5437 POLR2H MIM:606023|HGNC:HGNC:9195|Ensembl:ENSG00000163882|Vega:OTTHUMG00000156746 +5438 POLR2I MIM:180662|HGNC:HGNC:9196|Ensembl:ENSG00000105258|Vega:OTTHUMG00000181749 +5439 POLR2J MIM:604150|HGNC:HGNC:9197|Ensembl:ENSG00000005075|Vega:OTTHUMG00000150387 +5440 POLR2K MIM:606033|HGNC:HGNC:9198|Ensembl:ENSG00000147669|Vega:OTTHUMG00000164705 +5441 POLR2L MIM:601189|HGNC:HGNC:9199|Ensembl:ENSG00000177700|Vega:OTTHUMG00000133316 +5442 POLRMT MIM:601778|HGNC:HGNC:9200|Ensembl:ENSG00000099821|Vega:OTTHUMG00000180611 +5443 POMC MIM:176830|HGNC:HGNC:9201|Ensembl:ENSG00000115138|Vega:OTTHUMG00000094764 +5444 PON1 MIM:168820|HGNC:HGNC:9204|Ensembl:ENSG00000005421|Vega:OTTHUMG00000153894 +5445 PON2 MIM:602447|HGNC:HGNC:9205|Ensembl:ENSG00000105854|Vega:OTTHUMG00000153948 +5446 PON3 MIM:602720|HGNC:HGNC:9206|Ensembl:ENSG00000105852|Vega:OTTHUMG00000153917 +5447 POR MIM:124015|HGNC:HGNC:9208|Ensembl:ENSG00000127948|Vega:OTTHUMG00000130413 +5449 POU1F1 MIM:173110|HGNC:HGNC:9210|Ensembl:ENSG00000064835|Vega:OTTHUMG00000158992 +5450 POU2AF1 MIM:601206|HGNC:HGNC:9211|Ensembl:ENSG00000110777|Vega:OTTHUMG00000166659 +5451 POU2F1 MIM:164175|HGNC:HGNC:9212|Ensembl:ENSG00000143190|Vega:OTTHUMG00000034436 +5452 POU2F2 MIM:164176|HGNC:HGNC:9213|Ensembl:ENSG00000028277|Vega:OTTHUMG00000165991 +5453 POU3F1 MIM:602479|HGNC:HGNC:9214|Ensembl:ENSG00000185668|Vega:OTTHUMG00000000485 +5454 POU3F2 MIM:600494|HGNC:HGNC:9215|Ensembl:ENSG00000184486|Vega:OTTHUMG00000015258 +5455 POU3F3 MIM:602480|HGNC:HGNC:9216|Ensembl:ENSG00000198914|Vega:OTTHUMG00000153067 +5456 POU3F4 MIM:300039|HGNC:HGNC:9217|Ensembl:ENSG00000196767|Vega:OTTHUMG00000021919 +5457 POU4F1 MIM:601632|HGNC:HGNC:9218|Ensembl:ENSG00000152192|Vega:OTTHUMG00000017119 +5458 POU4F2 MIM:113725|HGNC:HGNC:9219|Ensembl:ENSG00000151615|Vega:OTTHUMG00000162045 +5459 POU4F3 MIM:602460|HGNC:HGNC:9220|Ensembl:ENSG00000091010|Vega:OTTHUMG00000129684 +5460 POU5F1 MIM:164177|HGNC:HGNC:9221|Ensembl:ENSG00000204531|Vega:OTTHUMG00000031206 +5462 POU5F1B MIM:615739|HGNC:HGNC:9223|Ensembl:ENSG00000212993|Vega:OTTHUMG00000157807 +5463 POU6F1 HGNC:HGNC:9224|Ensembl:ENSG00000184271|Vega:OTTHUMG00000169622 +5464 PPA1 MIM:179030|HGNC:HGNC:9226|Ensembl:ENSG00000180817|Vega:OTTHUMG00000018399 +5465 PPARA MIM:170998|HGNC:HGNC:9232|Ensembl:ENSG00000186951|Vega:OTTHUMG00000150443 +5467 PPARD MIM:600409|HGNC:HGNC:9235|Ensembl:ENSG00000112033|Vega:OTTHUMG00000014567 +5468 PPARG MIM:601487|HGNC:HGNC:9236|Ensembl:ENSG00000132170|Vega:OTTHUMG00000129764 +5469 MED1 MIM:604311|HGNC:HGNC:9234|Ensembl:ENSG00000125686|Vega:OTTHUMG00000133216 +5470 PPEF2 MIM:602256|HGNC:HGNC:9244|Ensembl:ENSG00000156194|Vega:OTTHUMG00000160915 +5471 PPAT MIM:172450|HGNC:HGNC:9238|Ensembl:ENSG00000128059|Vega:OTTHUMG00000128842 +5473 PPBP MIM:121010|HGNC:HGNC:9240|Ensembl:ENSG00000163736|Vega:OTTHUMG00000130008 +5475 PPEF1 MIM:300109|HGNC:HGNC:9243|Ensembl:ENSG00000086717|Vega:OTTHUMG00000021219 +5476 CTSA MIM:613111|HGNC:HGNC:9251|Ensembl:ENSG00000064601|Vega:OTTHUMG00000033078 +5478 PPIA MIM:123840|HGNC:HGNC:9253|Ensembl:ENSG00000196262|Vega:OTTHUMG00000023687 +5479 PPIB MIM:123841|HGNC:HGNC:9255|Ensembl:ENSG00000166794|Vega:OTTHUMG00000133018 +5480 PPIC MIM:123842|HGNC:HGNC:9256|Ensembl:ENSG00000168938|Vega:OTTHUMG00000128921 +5481 PPID MIM:601753|HGNC:HGNC:9257|Ensembl:ENSG00000171497|Vega:OTTHUMG00000161927 +5483 PPIAP11 HGNC:HGNC:9263 +5485 PPIAP13 HGNC:HGNC:9266 +5486 PPIAP14 HGNC:HGNC:9267 +5487 PPIAP15 HGNC:HGNC:9268 +5488 PPIAP16 HGNC:HGNC:9269 +5489 PPIAP7 HGNC:HGNC:9270 +5491 PPIAP9 HGNC:HGNC:9272 +5493 PPL MIM:602871|HGNC:HGNC:9273|Ensembl:ENSG00000118898|Vega:OTTHUMG00000129528 +5494 PPM1A MIM:606108|HGNC:HGNC:9275|Ensembl:ENSG00000100614|Vega:OTTHUMG00000140333 +5495 PPM1B MIM:603770|HGNC:HGNC:9276|Ensembl:ENSG00000138032|Vega:OTTHUMG00000128757 +5496 PPM1G MIM:605119|HGNC:HGNC:9278|Ensembl:ENSG00000115241|Vega:OTTHUMG00000097788 +5498 PPOX MIM:600923|HGNC:HGNC:9280|Ensembl:ENSG00000143224|Vega:OTTHUMG00000034342 +5499 PPP1CA MIM:176875|HGNC:HGNC:9281|Ensembl:ENSG00000172531|Vega:OTTHUMG00000167671 +5500 PPP1CB MIM:600590|HGNC:HGNC:9282|Ensembl:ENSG00000213639|Vega:OTTHUMG00000152011 +5501 PPP1CC MIM:176914|HGNC:HGNC:9283|Ensembl:ENSG00000186298|Vega:OTTHUMG00000169531 +5502 PPP1R1A MIM:613246|HGNC:HGNC:9286|Ensembl:ENSG00000135447|Vega:OTTHUMG00000169934 +5504 PPP1R2 MIM:601792|HGNC:HGNC:9288|Ensembl:ENSG00000184203|Vega:OTTHUMG00000155887 +5506 PPP1R3A MIM:600917|HGNC:HGNC:9291|Ensembl:ENSG00000154415|Vega:OTTHUMG00000156944 +5507 PPP1R3C MIM:602999|HGNC:HGNC:9293|Ensembl:ENSG00000119938|Vega:OTTHUMG00000018745 +5509 PPP1R3D MIM:603326|HGNC:HGNC:9294|Ensembl:ENSG00000132825|Vega:OTTHUMG00000032876 +5510 PPP1R7 MIM:602877|HGNC:HGNC:9295|Ensembl:ENSG00000115685|Vega:OTTHUMG00000133390 +5511 PPP1R8 MIM:602636|HGNC:HGNC:9296|Ensembl:ENSG00000117751|Vega:OTTHUMG00000003734 +5512 PPP1R8P1 HGNC:HGNC:9297 +5514 PPP1R10 MIM:603771|HGNC:HGNC:9284|Ensembl:ENSG00000204569|Vega:OTTHUMG00000031259 +5515 PPP2CA MIM:176915|HGNC:HGNC:9299|Ensembl:ENSG00000113575|Vega:OTTHUMG00000129119 +5516 PPP2CB MIM:176916|HGNC:HGNC:9300|Ensembl:ENSG00000104695|Vega:OTTHUMG00000163949 +5517 PPP2CBP1 HGNC:HGNC:9301 +5518 PPP2R1A MIM:605983|HGNC:HGNC:9302|Ensembl:ENSG00000105568|Vega:OTTHUMG00000137367 +5519 PPP2R1B MIM:603113|HGNC:HGNC:9303|Ensembl:ENSG00000137713|Vega:OTTHUMG00000166741 +5520 PPP2R2A MIM:604941|HGNC:HGNC:9304|Ensembl:ENSG00000221914|Vega:OTTHUMG00000163850 +5521 PPP2R2B MIM:604325|HGNC:HGNC:9305|Ensembl:ENSG00000156475|Vega:OTTHUMG00000163381 +5522 PPP2R2C MIM:605997|HGNC:HGNC:9306|Ensembl:ENSG00000074211|Vega:OTTHUMG00000090445 +5523 PPP2R3A MIM:604944|HGNC:HGNC:9307|Ensembl:ENSG00000073711|Vega:OTTHUMG00000159766 +5524 PTPA MIM:600756|HGNC:HGNC:9308|Ensembl:ENSG00000119383|Vega:OTTHUMG00000020774 +5525 PPP2R5A MIM:601643|HGNC:HGNC:9309|Ensembl:ENSG00000066027|Vega:OTTHUMG00000036750 +5526 PPP2R5B MIM:601644|HGNC:HGNC:9310|Ensembl:ENSG00000068971|Vega:OTTHUMG00000150043 +5527 PPP2R5C MIM:601645|HGNC:HGNC:9311|Ensembl:ENSG00000078304|Vega:OTTHUMG00000171597 +5528 PPP2R5D MIM:601646|HGNC:HGNC:9312|Ensembl:ENSG00000112640|Vega:OTTHUMG00000014716 +5529 PPP2R5E MIM:601647|HGNC:HGNC:9313|Ensembl:ENSG00000154001|Vega:OTTHUMG00000140341 +5530 PPP3CA MIM:114105|HGNC:HGNC:9314|Ensembl:ENSG00000138814|Vega:OTTHUMG00000133839 +5531 PPP4C MIM:602035|HGNC:HGNC:9319|Ensembl:ENSG00000149923|Vega:OTTHUMG00000132113 +5532 PPP3CB MIM:114106|HGNC:HGNC:9315|Ensembl:ENSG00000107758|Vega:OTTHUMG00000018472 +5533 PPP3CC MIM:114107|HGNC:HGNC:9316|Ensembl:ENSG00000120910|Vega:OTTHUMG00000163802 +5534 PPP3R1 MIM:601302|HGNC:HGNC:9317|Ensembl:ENSG00000221823|Vega:OTTHUMG00000129561 +5535 PPP3R2 MIM:613821|HGNC:HGNC:9318|Ensembl:ENSG00000188386|Vega:OTTHUMG00000020386 +5536 PPP5C MIM:600658|HGNC:HGNC:9322|Ensembl:ENSG00000011485|Vega:OTTHUMG00000134287 +5537 PPP6C MIM:612725|HGNC:HGNC:9323|Ensembl:ENSG00000119414|Vega:OTTHUMG00000020671 +5538 PPT1 MIM:600722|HGNC:HGNC:9325|Ensembl:ENSG00000131238|Vega:OTTHUMG00000004495 +5539 PPY MIM:167780|HGNC:HGNC:9327|Ensembl:ENSG00000108849|Vega:OTTHUMG00000181800 +5540 NPY4R MIM:601790|HGNC:HGNC:9329|Ensembl:ENSG00000204174|Vega:OTTHUMG00000018108 +5541 PR@ HGNC:HGNC:9335 +5542 PRB1 MIM:180989|HGNC:HGNC:9337|Ensembl:ENSG00000251655|Vega:OTTHUMG00000157263 +5544 PRB3 MIM:168840|HGNC:HGNC:9339|Ensembl:ENSG00000197870|Vega:OTTHUMG00000169065 +5545 PRB4 MIM:180990|HGNC:HGNC:9340|Ensembl:ENSG00000230657|Vega:OTTHUMG00000169116 +5546 PRCC MIM:179755|HGNC:HGNC:9343|Ensembl:ENSG00000143294|Vega:OTTHUMG00000041294 +5547 PRCP MIM:176785|HGNC:HGNC:9344|Ensembl:ENSG00000137509|Vega:OTTHUMG00000166899 +5548 PRD MIM:312550|HGNC:HGNC:9345 +5549 PRELP MIM:601914|HGNC:HGNC:9357|Ensembl:ENSG00000188783|Vega:OTTHUMG00000035911 +5550 PREP MIM:600400|HGNC:HGNC:9358|Ensembl:ENSG00000085377|Vega:OTTHUMG00000015297 +5551 PRF1 MIM:170280|HGNC:HGNC:9360|Ensembl:ENSG00000180644|Vega:OTTHUMG00000018412 +5552 SRGN MIM:177040|HGNC:HGNC:9361|Ensembl:ENSG00000122862|Vega:OTTHUMG00000018369 +5553 PRG2 MIM:605601|HGNC:HGNC:9362|Ensembl:ENSG00000186652|Vega:OTTHUMG00000167027 +5554 PRH1 MIM:168730|HGNC:HGNC:9366|Ensembl:ENSG00000231887|Vega:OTTHUMG00000186774 +5555 PRH2 MIM:168790|HGNC:HGNC:9367|Ensembl:ENSG00000134551|Vega:OTTHUMG00000168556 +5557 PRIM1 MIM:176635|HGNC:HGNC:9369|Ensembl:ENSG00000198056|Vega:OTTHUMG00000170034 +5558 PRIM2 MIM:176636|HGNC:HGNC:9370|Ensembl:ENSG00000146143|Vega:OTTHUMG00000016190 +5562 PRKAA1 MIM:602739|HGNC:HGNC:9376|Ensembl:ENSG00000132356|Vega:OTTHUMG00000162269 +5563 PRKAA2 MIM:600497|HGNC:HGNC:9377|Ensembl:ENSG00000162409|Vega:OTTHUMG00000008282 +5564 PRKAB1 MIM:602740|HGNC:HGNC:9378|Ensembl:ENSG00000111725|Vega:OTTHUMG00000168954 +5565 PRKAB2 MIM:602741|HGNC:HGNC:9379|Ensembl:ENSG00000131791|Vega:OTTHUMG00000014032 +5566 PRKACA MIM:601639|HGNC:HGNC:9380|Ensembl:ENSG00000072062|Vega:OTTHUMG00000182051 +5567 PRKACB MIM:176892|HGNC:HGNC:9381|Ensembl:ENSG00000142875|Vega:OTTHUMG00000009975 +5568 PRKACG MIM:176893|HGNC:HGNC:9382|Ensembl:ENSG00000165059|Vega:OTTHUMG00000019974 +5569 PKIA MIM:606059|HGNC:HGNC:9017|Ensembl:ENSG00000171033|Vega:OTTHUMG00000164618 +5570 PKIB MIM:606914|HGNC:HGNC:9018|Ensembl:ENSG00000135549|Vega:OTTHUMG00000015488 +5571 PRKAG1 MIM:602742|HGNC:HGNC:9385|Ensembl:ENSG00000181929|Vega:OTTHUMG00000170406 +5573 PRKAR1A MIM:188830|HGNC:HGNC:9388|Ensembl:ENSG00000108946|Vega:OTTHUMG00000180128 +5574 PRKAR1AP1 HGNC:HGNC:9389 +5575 PRKAR1B MIM:176911|HGNC:HGNC:9390|Ensembl:ENSG00000188191|Vega:OTTHUMG00000151411 +5576 PRKAR2A MIM:176910|HGNC:HGNC:9391|Ensembl:ENSG00000114302|Vega:OTTHUMG00000133540 +5577 PRKAR2B MIM:176912|HGNC:HGNC:9392|Ensembl:ENSG00000005249|Vega:OTTHUMG00000137418 +5578 PRKCA MIM:176960|HGNC:HGNC:9393|Ensembl:ENSG00000154229|Vega:OTTHUMG00000179533 +5579 PRKCB MIM:176970|HGNC:HGNC:9395|Ensembl:ENSG00000166501|Vega:OTTHUMG00000131615 +5580 PRKCD MIM:176977|HGNC:HGNC:9399|Ensembl:ENSG00000163932|Vega:OTTHUMG00000133659 +5581 PRKCE MIM:176975|HGNC:HGNC:9401|Ensembl:ENSG00000171132|Vega:OTTHUMG00000128817 +5582 PRKCG MIM:176980|HGNC:HGNC:9402|Ensembl:ENSG00000126583|Vega:OTTHUMG00000064846 +5583 PRKCH MIM:605437|HGNC:HGNC:9403|Ensembl:ENSG00000027075|Vega:OTTHUMG00000152341 +5584 PRKCI MIM:600539|HGNC:HGNC:9404|Ensembl:ENSG00000163558|Vega:OTTHUMG00000150214 +5585 PKN1 MIM:601032|HGNC:HGNC:9405|Ensembl:ENSG00000123143|Vega:OTTHUMG00000039611 +5586 PKN2 MIM:602549|HGNC:HGNC:9406|Ensembl:ENSG00000065243|Vega:OTTHUMG00000010074 +5587 PRKD1 MIM:605435|HGNC:HGNC:9407|Ensembl:ENSG00000184304|Vega:OTTHUMG00000140203 +5588 PRKCQ MIM:600448|HGNC:HGNC:9410|Ensembl:ENSG00000065675|Vega:OTTHUMG00000017623 +5589 PRKCSH MIM:177060|HGNC:HGNC:9411|Ensembl:ENSG00000130175|Vega:OTTHUMG00000182029 +5590 PRKCZ MIM:176982|HGNC:HGNC:9412|Ensembl:ENSG00000067606|Vega:OTTHUMG00000001238 +5591 PRKDC MIM:600899|HGNC:HGNC:9413|Ensembl:ENSG00000253729|Vega:OTTHUMG00000164239 +5592 PRKG1 MIM:176894|HGNC:HGNC:9414|Ensembl:ENSG00000185532|Vega:OTTHUMG00000018248 +5593 PRKG2 MIM:601591|HGNC:HGNC:9416|Ensembl:ENSG00000138669|Vega:OTTHUMG00000130296 +5594 MAPK1 MIM:176948|HGNC:HGNC:6871|Ensembl:ENSG00000100030|Vega:OTTHUMG00000030508 +5595 MAPK3 MIM:601795|HGNC:HGNC:6877|Ensembl:ENSG00000102882|Vega:OTTHUMG00000132149 +5596 MAPK4 MIM:176949|HGNC:HGNC:6878|Ensembl:ENSG00000141639|Vega:OTTHUMG00000179853 +5597 MAPK6 MIM:602904|HGNC:HGNC:6879|Ensembl:ENSG00000069956|Vega:OTTHUMG00000131891 +5598 MAPK7 MIM:602521|HGNC:HGNC:6880|Ensembl:ENSG00000166484|Vega:OTTHUMG00000059587 +5599 MAPK8 MIM:601158|HGNC:HGNC:6881|Ensembl:ENSG00000107643|Vega:OTTHUMG00000018172 +5600 MAPK11 MIM:602898|HGNC:HGNC:6873|Ensembl:ENSG00000185386|Vega:OTTHUMG00000150226 +5601 MAPK9 MIM:602896|HGNC:HGNC:6886|Ensembl:ENSG00000050748|Vega:OTTHUMG00000130934 +5602 MAPK10 MIM:602897|HGNC:HGNC:6872|Ensembl:ENSG00000109339|Vega:OTTHUMG00000130604 +5603 MAPK13 MIM:602899|HGNC:HGNC:6875|Ensembl:ENSG00000156711|Vega:OTTHUMG00000014587 +5604 MAP2K1 MIM:176872|HGNC:HGNC:6840|Ensembl:ENSG00000169032|Vega:OTTHUMG00000133196 +5605 MAP2K2 MIM:601263|HGNC:HGNC:6842|Ensembl:ENSG00000126934|Vega:OTTHUMG00000134286 +5606 MAP2K3 MIM:602315|HGNC:HGNC:6843|Ensembl:ENSG00000034152|Vega:OTTHUMG00000134322 +5607 MAP2K5 MIM:602520|HGNC:HGNC:6845|Ensembl:ENSG00000137764|Vega:OTTHUMG00000133264 +5608 MAP2K6 MIM:601254|HGNC:HGNC:6846|Ensembl:ENSG00000108984|Vega:OTTHUMG00000180311 +5609 MAP2K7 MIM:603014|HGNC:HGNC:6847|Ensembl:ENSG00000076984|Vega:OTTHUMG00000137368 +5610 EIF2AK2 MIM:176871|HGNC:HGNC:9437|Ensembl:ENSG00000055332|Vega:OTTHUMG00000100962 +5611 DNAJC3 MIM:601184|HGNC:HGNC:9439|Ensembl:ENSG00000102580|Vega:OTTHUMG00000017227 +5612 THAP12 MIM:607374|HGNC:HGNC:9440|Ensembl:ENSG00000137492|Vega:OTTHUMG00000165280 +5613 PRKX MIM:300083|HGNC:HGNC:9441|Ensembl:ENSG00000183943|Vega:OTTHUMG00000021087 +5615 PRKXP2 HGNC:HGNC:9443 +5616 PRKY MIM:400008|HGNC:HGNC:9444|Ensembl:ENSG00000099725 +5617 PRL MIM:176760|HGNC:HGNC:9445|Ensembl:ENSG00000172179|Vega:OTTHUMG00000016111 +5618 PRLR MIM:176761|HGNC:HGNC:9446|Ensembl:ENSG00000113494|Vega:OTTHUMG00000090789 +5619 PRM1 MIM:182880|HGNC:HGNC:9447|Ensembl:ENSG00000175646|Vega:OTTHUMG00000090521 +5620 PRM2 MIM:182890|HGNC:HGNC:9448|Ensembl:ENSG00000122304|Vega:OTTHUMG00000172317 +5621 PRNP MIM:176640|HGNC:HGNC:9449|Ensembl:ENSG00000171867|Vega:OTTHUMG00000031786 +5623 PSPN MIM:602921|HGNC:HGNC:9579|Ensembl:ENSG00000125650|Vega:OTTHUMG00000168086 +5624 PROC MIM:612283|HGNC:HGNC:9451|Ensembl:ENSG00000115718|Vega:OTTHUMG00000131528 +5625 PRODH MIM:606810|HGNC:HGNC:9453|Ensembl:ENSG00000100033|Vega:OTTHUMG00000150163 +5626 PROP1 MIM:601538|HGNC:HGNC:9455|Ensembl:ENSG00000175325|Vega:OTTHUMG00000130887 +5627 PROS1 MIM:176880|HGNC:HGNC:9456|Ensembl:ENSG00000184500|Vega:OTTHUMG00000150354 +5628 PROS2P HGNC:HGNC:9458 +5629 PROX1 MIM:601546|HGNC:HGNC:9459|Ensembl:ENSG00000117707|Vega:OTTHUMG00000036946 +5630 PRPH MIM:170710|HGNC:HGNC:9461|Ensembl:ENSG00000135406|Vega:OTTHUMG00000167140 +5631 PRPS1 MIM:311850|HGNC:HGNC:9462|Ensembl:ENSG00000147224|Vega:OTTHUMG00000022167 +5634 PRPS2 MIM:311860|HGNC:HGNC:9465|Ensembl:ENSG00000101911|Vega:OTTHUMG00000021139 +5635 PRPSAP1 MIM:601249|HGNC:HGNC:9466|Ensembl:ENSG00000161542|Vega:OTTHUMG00000155969 +5636 PRPSAP2 MIM:603762|HGNC:HGNC:9467|Ensembl:ENSG00000141127|Vega:OTTHUMG00000059406 +5638 PRRG1 MIM:300935|HGNC:HGNC:9469|Ensembl:ENSG00000130962|Vega:OTTHUMG00000021360 +5639 PRRG2 MIM:604429|HGNC:HGNC:9470|Ensembl:ENSG00000126460|Vega:OTTHUMG00000183153 +5640 PRS MIM:309610|HGNC:HGNC:9471 +5641 LGMN MIM:602620|HGNC:HGNC:9472|Ensembl:ENSG00000100600|Vega:OTTHUMG00000171199 +5643 PRSM2 HGNC:HGNC:9474 +5644 PRSS1 MIM:276000|HGNC:HGNC:9475|Ensembl:ENSG00000204983|Vega:OTTHUMG00000158923 +5645 PRSS2 MIM:601564|HGNC:HGNC:9483|Ensembl:ENSG00000275896|Vega:OTTHUMG00000158904 +5646 PRSS3 MIM:613578|HGNC:HGNC:9486|Ensembl:ENSG00000010438|Vega:OTTHUMG00000019798 +5648 MASP1 MIM:600521|HGNC:HGNC:6901|Ensembl:ENSG00000127241|Vega:OTTHUMG00000156461 +5649 RELN MIM:600514|HGNC:HGNC:9957|Ensembl:ENSG00000189056|Vega:OTTHUMG00000157247 +5650 KLK7 MIM:604438|HGNC:HGNC:6368|Ensembl:ENSG00000169035|Vega:OTTHUMG00000182917 +5651 TMPRSS15 MIM:606635|HGNC:HGNC:9490|Ensembl:ENSG00000154646|Vega:OTTHUMG00000074518 +5652 PRSS8 MIM:600823|HGNC:HGNC:9491|Ensembl:ENSG00000052344|Vega:OTTHUMG00000176750 +5653 KLK6 MIM:602652|HGNC:HGNC:6367|Ensembl:ENSG00000167755|Vega:OTTHUMG00000183098 +5654 HTRA1 MIM:602194|HGNC:HGNC:9476|Ensembl:ENSG00000166033|Vega:OTTHUMG00000019186 +5655 KLK10 MIM:602673|HGNC:HGNC:6358|Ensembl:ENSG00000129451|Vega:OTTHUMG00000182916 +5657 PRTN3 MIM:177020|HGNC:HGNC:9495|Ensembl:ENSG00000196415|Vega:OTTHUMG00000181838 +5660 PSAP MIM:176801|HGNC:HGNC:9498|Ensembl:ENSG00000197746|Vega:OTTHUMG00000018429 +5661 PSBP1 HGNC:HGNC:9499 +5662 PSD MIM:602327|HGNC:HGNC:9507|Ensembl:ENSG00000059915|Vega:OTTHUMG00000018954 +5663 PSEN1 MIM:104311|HGNC:HGNC:9508|Ensembl:ENSG00000080815|Vega:OTTHUMG00000141279 +5664 PSEN2 MIM:600759|HGNC:HGNC:9509|Ensembl:ENSG00000143801|Vega:OTTHUMG00000037563 +5669 PSG1 MIM:176390|HGNC:HGNC:9514|Ensembl:ENSG00000231924|Vega:OTTHUMG00000151123 +5670 PSG2 MIM:176391|HGNC:HGNC:9519|Ensembl:ENSG00000242221|Vega:OTTHUMG00000151547 +5671 PSG3 MIM:176392|HGNC:HGNC:9520|Ensembl:ENSG00000221826|Vega:OTTHUMG00000151120 +5672 PSG4 MIM:176393|HGNC:HGNC:9521|Ensembl:ENSG00000243137|Vega:OTTHUMG00000151544 +5673 PSG5 MIM:176394|HGNC:HGNC:9522|Ensembl:ENSG00000204941|Vega:OTTHUMG00000151539 +5675 PSG6 MIM:176395|HGNC:HGNC:9523|Ensembl:ENSG00000170848|Vega:OTTHUMG00000151127 +5676 PSG7 MIM:176396|HGNC:HGNC:9524|Ensembl:ENSG00000221878|Vega:OTTHUMG00000151125 +5678 PSG9 MIM:176398|HGNC:HGNC:9526|Ensembl:ENSG00000183668|Vega:OTTHUMG00000182826 +5680 PSG11 MIM:176401|HGNC:HGNC:9516|Ensembl:ENSG00000243130|Vega:OTTHUMG00000151546 +5681 PSKH1 MIM:177015|HGNC:HGNC:9529|Ensembl:ENSG00000159792|Vega:OTTHUMG00000137548 +5682 PSMA1 MIM:602854|HGNC:HGNC:9530|Ensembl:ENSG00000129084|Vega:OTTHUMG00000165825 +5683 PSMA2 MIM:176842|HGNC:HGNC:9531|Ensembl:ENSG00000106588|Ensembl:ENSG00000256646|Vega:OTTHUMG00000023916|Vega:OTTHUMG00000168259 +5684 PSMA3 MIM:176843|HGNC:HGNC:9532|Ensembl:ENSG00000100567|Vega:OTTHUMG00000140319 +5685 PSMA4 MIM:176846|HGNC:HGNC:9533|Ensembl:ENSG00000041357|Vega:OTTHUMG00000143859 +5686 PSMA5 MIM:176844|HGNC:HGNC:9534|Ensembl:ENSG00000143106|Vega:OTTHUMG00000012001 +5687 PSMA6 MIM:602855|HGNC:HGNC:9535|Ensembl:ENSG00000100902|Vega:OTTHUMG00000140221 +5688 PSMA7 MIM:606607|HGNC:HGNC:9536|Ensembl:ENSG00000101182|Vega:OTTHUMG00000032895 +5689 PSMB1 MIM:602017|HGNC:HGNC:9537|Ensembl:ENSG00000008018|Vega:OTTHUMG00000016087 +5690 PSMB2 MIM:602175|HGNC:HGNC:9539|Ensembl:ENSG00000126067|Vega:OTTHUMG00000004169 +5691 PSMB3 MIM:602176|HGNC:HGNC:9540|Ensembl:ENSG00000277791|Vega:OTTHUMG00000188503 +5692 PSMB4 MIM:602177|HGNC:HGNC:9541|Ensembl:ENSG00000159377|Vega:OTTHUMG00000012494 +5693 PSMB5 MIM:600306|HGNC:HGNC:9542|Ensembl:ENSG00000100804|Vega:OTTHUMG00000028713 +5694 PSMB6 MIM:600307|HGNC:HGNC:9543|Ensembl:ENSG00000142507|Vega:OTTHUMG00000090777 +5695 PSMB7 MIM:604030|HGNC:HGNC:9544|Ensembl:ENSG00000136930|Vega:OTTHUMG00000021042 +5696 PSMB8 MIM:177046|HGNC:HGNC:9545|Ensembl:ENSG00000204264|Vega:OTTHUMG00000031285 +5697 PYY MIM:600781|HGNC:HGNC:9748|Ensembl:ENSG00000131096|Vega:OTTHUMG00000181801 +5698 PSMB9 MIM:177045|HGNC:HGNC:9546|Ensembl:ENSG00000240065|Vega:OTTHUMG00000031287 +5699 PSMB10 MIM:176847|HGNC:HGNC:9538|Ensembl:ENSG00000205220|Vega:OTTHUMG00000137553 +5700 PSMC1 MIM:602706|HGNC:HGNC:9547|Ensembl:ENSG00000100764|Vega:OTTHUMG00000171019 +5701 PSMC2 MIM:154365|HGNC:HGNC:9548|Ensembl:ENSG00000161057|Vega:OTTHUMG00000157206 +5702 PSMC3 MIM:186852|HGNC:HGNC:9549|Ensembl:ENSG00000165916|Vega:OTTHUMG00000167692 +5703 PSMC3P1 HGNC:HGNC:9550 +5704 PSMC4 MIM:602707|HGNC:HGNC:9551|Ensembl:ENSG00000013275|Vega:OTTHUMG00000182577 +5705 PSMC5 MIM:601681|HGNC:HGNC:9552|Ensembl:ENSG00000087191|Vega:OTTHUMG00000179013 +5706 PSMC6 MIM:602708|HGNC:HGNC:9553|Ensembl:ENSG00000100519|Vega:OTTHUMG00000152333 +5707 PSMD1 HGNC:HGNC:9554|Ensembl:ENSG00000173692|Vega:OTTHUMG00000133223 +5708 PSMD2 MIM:606223|HGNC:HGNC:9559|Ensembl:ENSG00000175166|Vega:OTTHUMG00000156796 +5709 PSMD3 HGNC:HGNC:9560|Ensembl:ENSG00000108344|Vega:OTTHUMG00000133251 +5710 PSMD4 MIM:601648|HGNC:HGNC:9561|Ensembl:ENSG00000159352|Vega:OTTHUMG00000012349 +5711 PSMD5 MIM:604452|HGNC:HGNC:9563|Ensembl:ENSG00000095261|Vega:OTTHUMG00000020573 +5713 PSMD7 MIM:157970|HGNC:HGNC:9565|Ensembl:ENSG00000103035|Vega:OTTHUMG00000137601 +5714 PSMD8 HGNC:HGNC:9566|Ensembl:ENSG00000099341|Vega:OTTHUMG00000150691 +5715 PSMD9 MIM:603146|HGNC:HGNC:9567|Ensembl:ENSG00000110801|Vega:OTTHUMG00000168945 +5716 PSMD10 MIM:300880|HGNC:HGNC:9555|Ensembl:ENSG00000101843|Vega:OTTHUMG00000022177 +5717 PSMD11 MIM:604449|HGNC:HGNC:9556|Ensembl:ENSG00000108671|Vega:OTTHUMG00000132811 +5718 PSMD12 MIM:604450|HGNC:HGNC:9557|Ensembl:ENSG00000197170|Vega:OTTHUMG00000140376 +5719 PSMD13 MIM:603481|HGNC:HGNC:9558|Ensembl:ENSG00000185627|Vega:OTTHUMG00000119072 +5720 PSME1 MIM:600654|HGNC:HGNC:9568|Ensembl:ENSG00000092010|Vega:OTTHUMG00000028795 +5721 PSME2 MIM:602161|HGNC:HGNC:9569|Ensembl:ENSG00000100911|Vega:OTTHUMG00000028797 +5723 PSPH MIM:172480|HGNC:HGNC:9577|Ensembl:ENSG00000146733|Vega:OTTHUMG00000023441 +5724 PTAFR MIM:173393|HGNC:HGNC:9582|Ensembl:ENSG00000169403|Vega:OTTHUMG00000003953 +5725 PTBP1 MIM:600693|HGNC:HGNC:9583|Ensembl:ENSG00000011304|Vega:OTTHUMG00000181789 +5726 TAS2R38 MIM:607751|HGNC:HGNC:9584|Ensembl:ENSG00000257138|Vega:OTTHUMG00000158374 +5727 PTCH1 MIM:601309|HGNC:HGNC:9585|Ensembl:ENSG00000185920|Vega:OTTHUMG00000020280 +5728 PTEN MIM:601728|HGNC:HGNC:9588|Ensembl:ENSG00000171862|Vega:OTTHUMG00000018688 +5729 PTGDR MIM:604687|HGNC:HGNC:9591|Ensembl:ENSG00000168229|Vega:OTTHUMG00000140299 +5730 PTGDS MIM:176803|HGNC:HGNC:9592|Ensembl:ENSG00000107317|Ensembl:ENSG00000284341|Vega:OTTHUMG00000020957 +5731 PTGER1 MIM:176802|HGNC:HGNC:9593|Ensembl:ENSG00000160951|Vega:OTTHUMG00000039610 +5732 PTGER2 MIM:176804|HGNC:HGNC:9594|Ensembl:ENSG00000125384|Vega:OTTHUMG00000140300 +5733 PTGER3 MIM:176806|HGNC:HGNC:9595|Ensembl:ENSG00000050628|Vega:OTTHUMG00000009399 +5734 PTGER4 MIM:601586|HGNC:HGNC:9596|Ensembl:ENSG00000171522|Vega:OTTHUMG00000094769 +5735 PTGER4P1 HGNC:HGNC:9597 +5736 PTGER4P2 HGNC:HGNC:9598 +5737 PTGFR MIM:600563|HGNC:HGNC:9600|Ensembl:ENSG00000122420|Vega:OTTHUMG00000009644 +5738 PTGFRN MIM:601204|HGNC:HGNC:9601|Ensembl:ENSG00000134247|Vega:OTTHUMG00000012028 +5739 PTGIR MIM:600022|HGNC:HGNC:9602|Ensembl:ENSG00000160013|Vega:OTTHUMG00000183429 +5740 PTGIS MIM:601699|HGNC:HGNC:9603|Ensembl:ENSG00000124212|Vega:OTTHUMG00000033077 +5741 PTH MIM:168450|HGNC:HGNC:9606|Ensembl:ENSG00000152266|Vega:OTTHUMG00000165785 +5742 PTGS1 MIM:176805|HGNC:HGNC:9604|Ensembl:ENSG00000095303|Vega:OTTHUMG00000020605 +5743 PTGS2 MIM:600262|HGNC:HGNC:9605|Ensembl:ENSG00000073756|Vega:OTTHUMG00000035473 +5744 PTHLH MIM:168470|HGNC:HGNC:9607|Ensembl:ENSG00000087494|Vega:OTTHUMG00000169221 +5745 PTH1R MIM:168468|HGNC:HGNC:9608|Ensembl:ENSG00000160801|Vega:OTTHUMG00000133515 +5746 PTH2R MIM:601469|HGNC:HGNC:9609|Ensembl:ENSG00000144407|Vega:OTTHUMG00000132960 +5747 PTK2 MIM:600758|HGNC:HGNC:9611|Ensembl:ENSG00000169398|Vega:OTTHUMG00000067438 +5753 PTK6 MIM:602004|HGNC:HGNC:9617|Ensembl:ENSG00000101213|Vega:OTTHUMG00000033039 +5754 PTK7 MIM:601890|HGNC:HGNC:9618|Ensembl:ENSG00000112655|Vega:OTTHUMG00000014721 +5756 TWF1 MIM:610932|HGNC:HGNC:9620|Ensembl:ENSG00000151239|Vega:OTTHUMG00000169426 +5757 PTMA MIM:188390|HGNC:HGNC:9623|Ensembl:ENSG00000187514|Vega:OTTHUMG00000153810 +5758 PTMAP1 HGNC:HGNC:9624 +5759 PTMAP2 HGNC:HGNC:9625 +5760 PTMAP3 HGNC:HGNC:9626 +5761 PTMAP4 HGNC:HGNC:9627 +5763 PTMS MIM:168440|HGNC:HGNC:9629|Ensembl:ENSG00000159335|Vega:OTTHUMG00000169196 +5764 PTN MIM:162095|HGNC:HGNC:9630|Ensembl:ENSG00000105894|Vega:OTTHUMG00000155709 +5765 PTOS1 MIM:178300|HGNC:HGNC:9631 +5767 PTP4A2P1 HGNC:HGNC:9637 +5768 QSOX1 MIM:603120|HGNC:HGNC:9756|Ensembl:ENSG00000116260|Vega:OTTHUMG00000035256 +5769 PTP4A2P2 HGNC:HGNC:9638 +5770 PTPN1 MIM:176885|HGNC:HGNC:9642|Ensembl:ENSG00000196396|Vega:OTTHUMG00000032729 +5771 PTPN2 MIM:176887|HGNC:HGNC:9650|Ensembl:ENSG00000175354|Vega:OTTHUMG00000131702 +5774 PTPN3 MIM:176877|HGNC:HGNC:9655|Ensembl:ENSG00000070159|Vega:OTTHUMG00000020475 +5775 PTPN4 MIM:176878|HGNC:HGNC:9656|Ensembl:ENSG00000088179|Vega:OTTHUMG00000131436 +5777 PTPN6 MIM:176883|HGNC:HGNC:9658|Ensembl:ENSG00000111679|Vega:OTTHUMG00000168518 +5778 PTPN7 MIM:176889|HGNC:HGNC:9659|Ensembl:ENSG00000143851|Vega:OTTHUMG00000035931 +5780 PTPN9 MIM:600768|HGNC:HGNC:9661|Ensembl:ENSG00000169410|Vega:OTTHUMG00000142838 +5781 PTPN11 MIM:176876|HGNC:HGNC:9644|Ensembl:ENSG00000179295|Vega:OTTHUMG00000134334 +5782 PTPN12 MIM:600079|HGNC:HGNC:9645|Ensembl:ENSG00000127947|Vega:OTTHUMG00000023501 +5783 PTPN13 MIM:600267|HGNC:HGNC:9646|Ensembl:ENSG00000163629|Vega:OTTHUMG00000160968 +5784 PTPN14 MIM:603155|HGNC:HGNC:9647|Ensembl:ENSG00000152104|Vega:OTTHUMG00000037039 +5786 PTPRA MIM:176884|HGNC:HGNC:9664|Ensembl:ENSG00000132670|Vega:OTTHUMG00000031718 +5787 PTPRB MIM:176882|HGNC:HGNC:9665|Ensembl:ENSG00000127329|Vega:OTTHUMG00000169499 +5788 PTPRC MIM:151460|HGNC:HGNC:9666|Ensembl:ENSG00000081237|Vega:OTTHUMG00000035702 +5789 PTPRD MIM:601598|HGNC:HGNC:9668|Ensembl:ENSG00000153707|Vega:OTTHUMG00000021005 +5790 PTPRCAP MIM:601577|HGNC:HGNC:9667|Ensembl:ENSG00000213402|Vega:OTTHUMG00000150325 +5791 PTPRE MIM:600926|HGNC:HGNC:9669|Ensembl:ENSG00000132334|Vega:OTTHUMG00000019254 +5792 PTPRF MIM:179590|HGNC:HGNC:9670|Ensembl:ENSG00000142949|Vega:OTTHUMG00000007501 +5793 PTPRG MIM:176886|HGNC:HGNC:9671|Ensembl:ENSG00000144724|Vega:OTTHUMG00000158660 +5794 PTPRH MIM:602510|HGNC:HGNC:9672|Ensembl:ENSG00000080031|Vega:OTTHUMG00000180701 +5795 PTPRJ MIM:600925|HGNC:HGNC:9673|Ensembl:ENSG00000149177|Vega:OTTHUMG00000166573 +5796 PTPRK MIM:602545|HGNC:HGNC:9674|Ensembl:ENSG00000152894|Vega:OTTHUMG00000015536 +5797 PTPRM MIM:176888|HGNC:HGNC:9675|Ensembl:ENSG00000173482|Vega:OTTHUMG00000131575 +5798 PTPRN MIM:601773|HGNC:HGNC:9676|Ensembl:ENSG00000054356|Vega:OTTHUMG00000133129 +5799 PTPRN2 MIM:601698|HGNC:HGNC:9677|Ensembl:ENSG00000155093|Vega:OTTHUMG00000152646 +5800 PTPRO MIM:600579|HGNC:HGNC:9678|Ensembl:ENSG00000151490|Vega:OTTHUMG00000168786 +5801 PTPRR MIM:602853|HGNC:HGNC:9680|Ensembl:ENSG00000153233|Vega:OTTHUMG00000169502 +5802 PTPRS MIM:601576|HGNC:HGNC:9681|Ensembl:ENSG00000105426|Vega:OTTHUMG00000180325 +5803 PTPRZ1 MIM:176891|HGNC:HGNC:9685|Ensembl:ENSG00000106278|Vega:OTTHUMG00000157057 +5804 PTPRZ2 MIM:604008|HGNC:HGNC:9686 +5805 PTS MIM:612719|HGNC:HGNC:9689|Ensembl:ENSG00000150787|Vega:OTTHUMG00000167167 +5806 PTX3 MIM:602492|HGNC:HGNC:9692|Ensembl:ENSG00000163661|Vega:OTTHUMG00000158750 +5810 RAD1 MIM:603153|HGNC:HGNC:9806|Ensembl:ENSG00000113456|Vega:OTTHUMG00000090783 +5813 PURA MIM:600473|HGNC:HGNC:9701|Ensembl:ENSG00000185129|Vega:OTTHUMG00000129242 +5814 PURB MIM:608887|HGNC:HGNC:9702|Ensembl:ENSG00000146676|Vega:OTTHUMG00000023578 +5816 PVALB MIM:168890|HGNC:HGNC:9704|Ensembl:ENSG00000100362|Vega:OTTHUMG00000150547 +5817 PVR MIM:173850|HGNC:HGNC:9705|Ensembl:ENSG00000073008|Vega:OTTHUMG00000151527 +5818 NECTIN1 MIM:600644|HGNC:HGNC:9706|Ensembl:ENSG00000110400|Vega:OTTHUMG00000166177 +5819 NECTIN2 MIM:600798|HGNC:HGNC:9707|Ensembl:ENSG00000130202|Vega:OTTHUMG00000180839 +5820 PVT1 MIM:165140|HGNC:HGNC:9709|Ensembl:ENSG00000249859 +5822 PWP2 MIM:601475|HGNC:HGNC:9711|Ensembl:ENSG00000241945|Vega:OTTHUMG00000086893 +5824 PEX19 MIM:600279|HGNC:HGNC:9713|Ensembl:ENSG00000162735|Vega:OTTHUMG00000033112 +5825 ABCD3 MIM:170995|HGNC:HGNC:67|Ensembl:ENSG00000117528|Vega:OTTHUMG00000010717 +5826 ABCD4 MIM:603214|HGNC:HGNC:68|Ensembl:ENSG00000119688|Vega:OTTHUMG00000171207 +5827 PXMP2 MIM:617399|HGNC:HGNC:9716|Ensembl:ENSG00000176894|Vega:OTTHUMG00000168019 +5828 PEX2 MIM:170993|HGNC:HGNC:9717|Ensembl:ENSG00000164751|Vega:OTTHUMG00000164530 +5829 PXN MIM:602505|HGNC:HGNC:9718|Ensembl:ENSG00000089159|Vega:OTTHUMG00000169169 +5830 PEX5 MIM:600414|HGNC:HGNC:9719|Ensembl:ENSG00000139197|Vega:OTTHUMG00000168175 +5831 PYCR1 MIM:179035|HGNC:HGNC:9721|Ensembl:ENSG00000183010|Vega:OTTHUMG00000178436 +5832 ALDH18A1 MIM:138250|HGNC:HGNC:9722|Ensembl:ENSG00000059573|Vega:OTTHUMG00000018815 +5833 PCYT2 MIM:602679|HGNC:HGNC:8756|Ensembl:ENSG00000185813|Vega:OTTHUMG00000177956 +5834 PYGB MIM:138550|HGNC:HGNC:9723|Ensembl:ENSG00000100994|Vega:OTTHUMG00000032117 +5836 PYGL MIM:613741|HGNC:HGNC:9725|Ensembl:ENSG00000100504|Vega:OTTHUMG00000166596 +5837 PYGM MIM:608455|HGNC:HGNC:9726|Ensembl:ENSG00000068976|Vega:OTTHUMG00000066835 +5858 PZP MIM:176420|HGNC:HGNC:9750|Ensembl:ENSG00000126838|Vega:OTTHUMG00000154915 +5859 QARS MIM:603727|HGNC:HGNC:9751|Ensembl:ENSG00000172053|Vega:OTTHUMG00000156774 +5860 QDPR MIM:612676|HGNC:HGNC:9752|Ensembl:ENSG00000151552|Vega:OTTHUMG00000128537 +5861 RAB1A MIM:179508|HGNC:HGNC:9758|Ensembl:ENSG00000138069|Vega:OTTHUMG00000152725 +5862 RAB2A MIM:179509|HGNC:HGNC:9763|Ensembl:ENSG00000104388|Vega:OTTHUMG00000134298 +5863 RGL2 MIM:602306|HGNC:HGNC:9769|Ensembl:ENSG00000237441|Vega:OTTHUMG00000031072 +5864 RAB3A MIM:179490|HGNC:HGNC:9777|Ensembl:ENSG00000105649|Vega:OTTHUMG00000137378 +5865 RAB3B MIM:179510|HGNC:HGNC:9778|Ensembl:ENSG00000169213|Vega:OTTHUMG00000008627 +5866 RAB3IL1 HGNC:HGNC:9780|Ensembl:ENSG00000167994|Vega:OTTHUMG00000167524 +5867 RAB4A MIM:179511|HGNC:HGNC:9781|Ensembl:ENSG00000168118|Vega:OTTHUMG00000037627 +5868 RAB5A MIM:179512|HGNC:HGNC:9783|Ensembl:ENSG00000144566|Vega:OTTHUMG00000129889 +5869 RAB5B MIM:179514|HGNC:HGNC:9784|Ensembl:ENSG00000111540|Vega:OTTHUMG00000169682 +5870 RAB6A MIM:179513|HGNC:HGNC:9786|Ensembl:ENSG00000175582|Vega:OTTHUMG00000134308 +5871 MAP4K2 MIM:603166|HGNC:HGNC:6864|Ensembl:ENSG00000168067|Vega:OTTHUMG00000045328 +5872 RAB13 MIM:602672|HGNC:HGNC:9762|Ensembl:ENSG00000143545|Vega:OTTHUMG00000036589 +5873 RAB27A MIM:603868|HGNC:HGNC:9766|Ensembl:ENSG00000069974|Vega:OTTHUMG00000131959 +5874 RAB27B MIM:603869|HGNC:HGNC:9767|Ensembl:ENSG00000041353|Vega:OTTHUMG00000132710 +5875 RABGGTA MIM:601905|HGNC:HGNC:9795|Ensembl:ENSG00000100949|Vega:OTTHUMG00000171838 +5876 RABGGTB MIM:179080|HGNC:HGNC:9796|Ensembl:ENSG00000137955|Vega:OTTHUMG00000009786 +5877 RABIF MIM:603417|HGNC:HGNC:9797|Ensembl:ENSG00000183155|Vega:OTTHUMG00000041400 +5878 RAB5C MIM:604037|HGNC:HGNC:9785|Ensembl:ENSG00000108774|Vega:OTTHUMG00000169703 +5879 RAC1 MIM:602048|HGNC:HGNC:9801|Ensembl:ENSG00000136238|Vega:OTTHUMG00000023540 +5880 RAC2 MIM:602049|HGNC:HGNC:9802|Ensembl:ENSG00000128340|Vega:OTTHUMG00000150540 +5881 RAC3 MIM:602050|HGNC:HGNC:9803|Ensembl:ENSG00000169750|Vega:OTTHUMG00000178455 +5883 RAD9A MIM:603761|HGNC:HGNC:9827|Ensembl:ENSG00000172613|Vega:OTTHUMG00000167670 +5884 RAD17 MIM:603139|HGNC:HGNC:9807|Ensembl:ENSG00000152942|Vega:OTTHUMG00000099357 +5885 RAD21 MIM:606462|HGNC:HGNC:9811|Ensembl:ENSG00000164754|Vega:OTTHUMG00000164959 +5886 RAD23A MIM:600061|HGNC:HGNC:9812|Ensembl:ENSG00000179262|Vega:OTTHUMG00000180723 +5887 RAD23B MIM:600062|HGNC:HGNC:9813|Ensembl:ENSG00000119318|Vega:OTTHUMG00000020446 +5888 RAD51 MIM:179617|HGNC:HGNC:9817|Ensembl:ENSG00000051180|Vega:OTTHUMG00000130067 +5889 RAD51C MIM:602774|HGNC:HGNC:9820|Ensembl:ENSG00000108384|Vega:OTTHUMG00000141292 +5890 RAD51B MIM:602948|HGNC:HGNC:9822|Ensembl:ENSG00000182185|Vega:OTTHUMG00000157530 +5891 MOK MIM:605762|HGNC:HGNC:9833|Ensembl:ENSG00000080823|Vega:OTTHUMG00000164896 +5892 RAD51D MIM:602954|HGNC:HGNC:9823|Ensembl:ENSG00000185379|Vega:OTTHUMG00000132930 +5893 RAD52 MIM:600392|HGNC:HGNC:9824|Ensembl:ENSG00000002016|Vega:OTTHUMG00000090361 +5894 RAF1 MIM:164760|HGNC:HGNC:9829|Ensembl:ENSG00000132155|Vega:OTTHUMG00000129789 +5896 RAG1 MIM:179615|HGNC:HGNC:9831|Ensembl:ENSG00000166349|Vega:OTTHUMG00000166392 +5897 RAG2 MIM:179616|HGNC:HGNC:9832|Ensembl:ENSG00000175097|Vega:OTTHUMG00000166393 +5898 RALA MIM:179550|HGNC:HGNC:9839|Ensembl:ENSG00000006451|Vega:OTTHUMG00000128775 +5899 RALB MIM:179551|HGNC:HGNC:9840|Ensembl:ENSG00000144118|Vega:OTTHUMG00000131435 +5900 RALGDS MIM:601619|HGNC:HGNC:9842|Ensembl:ENSG00000160271|Vega:OTTHUMG00000020858 +5901 RAN MIM:601179|HGNC:HGNC:9846|Ensembl:ENSG00000132341|Vega:OTTHUMG00000134328 +5902 RANBP1 MIM:601180|HGNC:HGNC:9847|Ensembl:ENSG00000099901|Vega:OTTHUMG00000150490 +5903 RANBP2 MIM:601181|HGNC:HGNC:9848|Ensembl:ENSG00000153201|Vega:OTTHUMG00000130981 +5905 RANGAP1 MIM:602362|HGNC:HGNC:9854|Ensembl:ENSG00000100401|Vega:OTTHUMG00000150940 +5906 RAP1A MIM:179520|HGNC:HGNC:9855|Ensembl:ENSG00000116473|Vega:OTTHUMG00000011959 +5907 RAP1AP HGNC:HGNC:9856 +5908 RAP1B MIM:179530|HGNC:HGNC:9857|Ensembl:ENSG00000127314|Vega:OTTHUMG00000133660 +5909 RAP1GAP MIM:600278|HGNC:HGNC:9858|Ensembl:ENSG00000076864|Vega:OTTHUMG00000007513 +5910 RAP1GDS1 MIM:179502|HGNC:HGNC:9859|Ensembl:ENSG00000138698|Vega:OTTHUMG00000160987 +5911 RAP2A MIM:179540|HGNC:HGNC:9861|Ensembl:ENSG00000125249|Vega:OTTHUMG00000017240 +5912 RAP2B MIM:179541|HGNC:HGNC:9862|Ensembl:ENSG00000181467|Vega:OTTHUMG00000159655 +5913 RAPSN MIM:601592|HGNC:HGNC:9863|Ensembl:ENSG00000165917|Vega:OTTHUMG00000166891 +5914 RARA MIM:180240|HGNC:HGNC:9864|Ensembl:ENSG00000131759|Vega:OTTHUMG00000133328 +5915 RARB MIM:180220|HGNC:HGNC:9865|Ensembl:ENSG00000077092|Vega:OTTHUMG00000130480 +5916 RARG MIM:180190|HGNC:HGNC:9866|Ensembl:ENSG00000172819|Vega:OTTHUMG00000048077 +5917 RARS MIM:107820|HGNC:HGNC:9870|Ensembl:ENSG00000113643|Vega:OTTHUMG00000130411 +5918 RARRES1 MIM:605090|HGNC:HGNC:9867|Ensembl:ENSG00000118849|Vega:OTTHUMG00000158834 +5919 RARRES2 MIM:601973|HGNC:HGNC:9868|Ensembl:ENSG00000106538|Vega:OTTHUMG00000158325 +5920 RARRES3 MIM:605092|HGNC:HGNC:9869|Ensembl:ENSG00000133321|Vega:OTTHUMG00000167850 +5921 RASA1 MIM:139150|HGNC:HGNC:9871|Ensembl:ENSG00000145715|Vega:OTTHUMG00000162605 +5922 RASA2 MIM:601589|HGNC:HGNC:9872|Ensembl:ENSG00000155903|Vega:OTTHUMG00000160221 +5923 RASGRF1 MIM:606600|HGNC:HGNC:9875|Ensembl:ENSG00000058335|Vega:OTTHUMG00000144172 +5924 RASGRF2 MIM:606614|HGNC:HGNC:9876|Ensembl:ENSG00000113319|Vega:OTTHUMG00000119015 +5925 RB1 MIM:614041|HGNC:HGNC:9884|Ensembl:ENSG00000139687|Vega:OTTHUMG00000016900 +5926 ARID4A MIM:180201|HGNC:HGNC:9885|Ensembl:ENSG00000032219|Vega:OTTHUMG00000140320 +5927 KDM5A MIM:180202|HGNC:HGNC:9886|Ensembl:ENSG00000073614|Vega:OTTHUMG00000168055 +5928 RBBP4 MIM:602923|HGNC:HGNC:9887|Ensembl:ENSG00000162521|Vega:OTTHUMG00000007998 +5929 RBBP5 MIM:600697|HGNC:HGNC:9888|Ensembl:ENSG00000117222|Vega:OTTHUMG00000037104 +5930 RBBP6 MIM:600938|HGNC:HGNC:9889|Ensembl:ENSG00000122257|Vega:OTTHUMG00000096991 +5931 RBBP7 MIM:300825|HGNC:HGNC:9890|Ensembl:ENSG00000102054|Vega:OTTHUMG00000021198 +5932 RBBP8 MIM:604124|HGNC:HGNC:9891|Ensembl:ENSG00000101773|Vega:OTTHUMG00000131769 +5933 RBL1 MIM:116957|HGNC:HGNC:9893|Ensembl:ENSG00000080839|Vega:OTTHUMG00000032406 +5934 RBL2 MIM:180203|HGNC:HGNC:9894|Ensembl:ENSG00000103479|Vega:OTTHUMG00000133198 +5935 RBM3 MIM:300027|HGNC:HGNC:9900|Ensembl:ENSG00000102317|Vega:OTTHUMG00000024121 +5936 RBM4 MIM:602571|HGNC:HGNC:9901|Ensembl:ENSG00000173933|Vega:OTTHUMG00000154171 +5937 RBMS1 MIM:602310|HGNC:HGNC:9907|Ensembl:ENSG00000153250|Vega:OTTHUMG00000132031 +5938 RBMS1P1 HGNC:HGNC:9908 +5939 RBMS2 MIM:602387|HGNC:HGNC:9909|Ensembl:ENSG00000076067|Vega:OTTHUMG00000170488 +5940 RBMY1A1 MIM:400006|HGNC:HGNC:9912|Ensembl:ENSG00000234414|Vega:OTTHUMG00000043592 +5942 RBMY1C HGNC:HGNC:9914 +5944 RBMY1HP HGNC:HGNC:9916 +5945 RBMY2AP HGNC:HGNC:9917 +5947 RBP1 MIM:180260|HGNC:HGNC:9919|Ensembl:ENSG00000114115|Vega:OTTHUMG00000155751 +5948 RBP2 MIM:180280|HGNC:HGNC:9920|Ensembl:ENSG00000114113|Vega:OTTHUMG00000159956 +5949 RBP3 MIM:180290|HGNC:HGNC:9921|Ensembl:ENSG00000265203|Vega:OTTHUMG00000188321 +5950 RBP4 MIM:180250|HGNC:HGNC:9922|Ensembl:ENSG00000138207|Vega:OTTHUMG00000018773 +5953 RCD1 MIM:180020|HGNC:HGNC:9930 +5954 RCN1 MIM:602735|HGNC:HGNC:9934|Ensembl:ENSG00000049449|Vega:OTTHUMG00000166227 +5955 RCN2 MIM:602584|HGNC:HGNC:9935|Ensembl:ENSG00000117906|Vega:OTTHUMG00000143730 +5956 OPN1LW MIM:300822|HGNC:HGNC:9936|Ensembl:ENSG00000102076|Vega:OTTHUMG00000034295 +5957 RCVRN MIM:179618|HGNC:HGNC:9937|Ensembl:ENSG00000109047|Vega:OTTHUMG00000130268 +5959 RDH5 MIM:601617|HGNC:HGNC:9940|Ensembl:ENSG00000135437|Vega:OTTHUMG00000170126 +5961 PRPH2 MIM:179605|HGNC:HGNC:9942|Ensembl:ENSG00000112619|Vega:OTTHUMG00000014701 +5962 RDX MIM:179410|HGNC:HGNC:9944|Ensembl:ENSG00000137710|Vega:OTTHUMG00000166574 +5964 RDXP2 HGNC:HGNC:9946 +5965 RECQL MIM:600537|HGNC:HGNC:9948|Ensembl:ENSG00000004700|Vega:OTTHUMG00000169131 +5966 REL MIM:164910|HGNC:HGNC:9954|Ensembl:ENSG00000162924|Vega:OTTHUMG00000129418 +5967 REG1A MIM:167770|HGNC:HGNC:9951|Ensembl:ENSG00000115386|Vega:OTTHUMG00000130016 +5968 REG1B MIM:167771|HGNC:HGNC:9952|Ensembl:ENSG00000172023|Vega:OTTHUMG00000130019 +5969 REG1CP HGNC:HGNC:9953 +5970 RELA MIM:164014|HGNC:HGNC:9955|Ensembl:ENSG00000173039|Vega:OTTHUMG00000166566 +5971 RELB MIM:604758|HGNC:HGNC:9956|Ensembl:ENSG00000104856|Vega:OTTHUMG00000162116 +5972 REN MIM:179820|HGNC:HGNC:9958|Ensembl:ENSG00000143839|Vega:OTTHUMG00000036059 +5973 RENBP MIM:312420|HGNC:HGNC:9959|Ensembl:ENSG00000102032|Vega:OTTHUMG00000024224 +5975 RENS2 HGNC:HGNC:9961 +5976 UPF1 MIM:601430|HGNC:HGNC:9962|Ensembl:ENSG00000005007|Vega:OTTHUMG00000183025 +5977 DPF2 MIM:601671|HGNC:HGNC:9964|Ensembl:ENSG00000133884|Vega:OTTHUMG00000165985 +5978 REST MIM:600571|HGNC:HGNC:9966|Ensembl:ENSG00000084093|Vega:OTTHUMG00000128770 +5979 RET MIM:164761|HGNC:HGNC:9967|Ensembl:ENSG00000165731|Vega:OTTHUMG00000018024 +5980 REV3L MIM:602776|HGNC:HGNC:9968|Ensembl:ENSG00000009413|Vega:OTTHUMG00000016318 +5981 RFC1 MIM:102579|HGNC:HGNC:9969|Ensembl:ENSG00000035928|Vega:OTTHUMG00000099363 +5982 RFC2 MIM:600404|HGNC:HGNC:9970|Ensembl:ENSG00000049541|Vega:OTTHUMG00000023239 +5983 RFC3 MIM:600405|HGNC:HGNC:9971|Ensembl:ENSG00000133119|Vega:OTTHUMG00000016715 +5984 RFC4 MIM:102577|HGNC:HGNC:9972|Ensembl:ENSG00000163918|Vega:OTTHUMG00000156515 +5985 RFC5 MIM:600407|HGNC:HGNC:9973|Ensembl:ENSG00000111445|Vega:OTTHUMG00000156438 +5986 RFNG MIM:602578|HGNC:HGNC:9974|Ensembl:ENSG00000169733|Vega:OTTHUMG00000178512 +5987 TRIM27 MIM:602165|HGNC:HGNC:9975|Ensembl:ENSG00000204713|Vega:OTTHUMG00000031215 +5988 RFPL1 MIM:605968|HGNC:HGNC:9977|Ensembl:ENSG00000128250|Vega:OTTHUMG00000150516 +5989 RFX1 MIM:600006|HGNC:HGNC:9982|Ensembl:ENSG00000132005|Vega:OTTHUMG00000181979 +5990 RFX2 MIM:142765|HGNC:HGNC:9983|Ensembl:ENSG00000087903|Vega:OTTHUMG00000180711 +5991 RFX3 MIM:601337|HGNC:HGNC:9984|Ensembl:ENSG00000080298|Vega:OTTHUMG00000019456 +5992 RFX4 MIM:603958|HGNC:HGNC:9985|Ensembl:ENSG00000111783|Vega:OTTHUMG00000169173 +5993 RFX5 MIM:601863|HGNC:HGNC:9986|Ensembl:ENSG00000143390|Vega:OTTHUMG00000012495 +5994 RFXAP MIM:601861|HGNC:HGNC:9988|Ensembl:ENSG00000133111|Vega:OTTHUMG00000016738 +5995 RGR MIM:600342|HGNC:HGNC:9990|Ensembl:ENSG00000148604|Vega:OTTHUMG00000018636 +5996 RGS1 MIM:600323|HGNC:HGNC:9991|Ensembl:ENSG00000090104|Vega:OTTHUMG00000035598 +5997 RGS2 MIM:600861|HGNC:HGNC:9998|Ensembl:ENSG00000116741|Vega:OTTHUMG00000035600 +5998 RGS3 MIM:602189|HGNC:HGNC:9999|Ensembl:ENSG00000138835|Vega:OTTHUMG00000021048 +5999 RGS4 MIM:602516|HGNC:HGNC:10000|Ensembl:ENSG00000117152|Vega:OTTHUMG00000034417 +6000 RGS7 MIM:602517|HGNC:HGNC:10003|Ensembl:ENSG00000182901|Vega:OTTHUMG00000040107 +6001 RGS10 MIM:602856|HGNC:HGNC:9992|Ensembl:ENSG00000148908|Vega:OTTHUMG00000019150 +6002 RGS12 MIM:602512|HGNC:HGNC:9994|Ensembl:ENSG00000159788|Vega:OTTHUMG00000090277 +6003 RGS13 MIM:607190|HGNC:HGNC:9995|Ensembl:ENSG00000127074|Vega:OTTHUMG00000035601 +6004 RGS16 MIM:602514|HGNC:HGNC:9997|Ensembl:ENSG00000143333|Vega:OTTHUMG00000035212 +6005 RHAG MIM:180297|HGNC:HGNC:10006|Ensembl:ENSG00000112077|Vega:OTTHUMG00000016377 +6006 RHCE MIM:111700|HGNC:HGNC:10008|Ensembl:ENSG00000188672|Vega:OTTHUMG00000007650 +6007 RHD MIM:111680|HGNC:HGNC:10009|Ensembl:ENSG00000187010|Vega:OTTHUMG00000003476 +6008 RHEBP1 HGNC:HGNC:10010 +6009 RHEB MIM:601293|HGNC:HGNC:10011|Ensembl:ENSG00000106615|Vega:OTTHUMG00000157330 +6010 RHO MIM:180380|HGNC:HGNC:10012|Ensembl:ENSG00000163914|Vega:OTTHUMG00000159542 +6011 GRK1 MIM:180381|HGNC:HGNC:10013|Ensembl:ENSG00000185974|Vega:OTTHUMG00000185528 +6012 RIEG2 MIM:601499|HGNC:HGNC:10015 +6013 RLN1 MIM:179730|HGNC:HGNC:10026|Ensembl:ENSG00000107018|Vega:OTTHUMG00000019495 +6014 RIT2 MIM:609592|HGNC:HGNC:10017|Ensembl:ENSG00000152214|Vega:OTTHUMG00000132611 +6015 RING1 MIM:602045|HGNC:HGNC:10018|Ensembl:ENSG00000204227|Vega:OTTHUMG00000031278 +6016 RIT1 MIM:609591|HGNC:HGNC:10023|Ensembl:ENSG00000143622|Vega:OTTHUMG00000014104 +6017 RLBP1 MIM:180090|HGNC:HGNC:10024|Ensembl:ENSG00000140522|Vega:OTTHUMG00000172884 +6018 RLF MIM:180610|HGNC:HGNC:10025|Ensembl:ENSG00000117000|Vega:OTTHUMG00000005763 +6019 RLN2 MIM:179740|HGNC:HGNC:10027|Ensembl:ENSG00000107014|Vega:OTTHUMG00000019496 +6022 RMD1 MIM:600332|HGNC:HGNC:10030 +6023 RMRP MIM:157660|HGNC:HGNC:10031|Ensembl:ENSG00000269900|Ensembl:ENSG00000277027 +6025 RN5S1@ MIM:180420|HGNC:HGNC:10034 +6029 RN7SL1 MIM:612177|HGNC:HGNC:10038|Ensembl:ENSG00000276168|Ensembl:ENSG00000283029 +6030 RN7SL4P HGNC:HGNC:10039 +6031 RN7SL5P HGNC:HGNC:10040 +6032 RN7SL6P HGNC:HGNC:10041 +6033 RN7SL7P HGNC:HGNC:10042 +6034 RN7SL8P HGNC:HGNC:10043 +6035 RNASE1 MIM:180440|HGNC:HGNC:10044|Ensembl:ENSG00000129538|Vega:OTTHUMG00000029603 +6036 RNASE2 MIM:131410|HGNC:HGNC:10045|Ensembl:ENSG00000169385|Vega:OTTHUMG00000029607 +6037 RNASE3 MIM:131398|HGNC:HGNC:10046|Ensembl:ENSG00000169397|Vega:OTTHUMG00000029604 +6038 RNASE4 MIM:601030|HGNC:HGNC:10047|Ensembl:ENSG00000258818|Vega:OTTHUMG00000029575 +6039 RNASE6 MIM:601981|HGNC:HGNC:10048|Ensembl:ENSG00000169413|Vega:OTTHUMG00000029585 +6041 RNASEL MIM:180435|HGNC:HGNC:10050|Ensembl:ENSG00000135828|Vega:OTTHUMG00000035213 +6043 SNORA63 MIM:180647|HGNC:HGNC:10106|Ensembl:ENSG00000200320 +6044 SNORA62 MIM:180646|HGNC:HGNC:10107|Ensembl:ENSG00000202363 +6045 RNF2 MIM:608985|HGNC:HGNC:10061|Ensembl:ENSG00000121481|Vega:OTTHUMG00000035391 +6046 BRD2 MIM:601540|HGNC:HGNC:1103|Ensembl:ENSG00000204256|Vega:OTTHUMG00000031241 +6047 RNF4 MIM:602850|HGNC:HGNC:10067|Ensembl:ENSG00000063978|Vega:OTTHUMG00000160516 +6048 RNF5 MIM:602677|HGNC:HGNC:10068|Ensembl:ENSG00000204308|Vega:OTTHUMG00000031093 +6049 RNF6 MIM:604242|HGNC:HGNC:10069|Ensembl:ENSG00000127870|Vega:OTTHUMG00000016614 +6050 RNH1 MIM:173320|HGNC:HGNC:10074|Ensembl:ENSG00000023191|Vega:OTTHUMG00000119086 +6051 RNPEP MIM:602675|HGNC:HGNC:10078|Ensembl:ENSG00000176393|Vega:OTTHUMG00000035866 +6052 RNR1 MIM:180450|HGNC:HGNC:10082 +6053 RNR2 MIM:180451|HGNC:HGNC:10083 +6054 RNR3 MIM:180452|HGNC:HGNC:10084 +6055 RNR4 MIM:180453|HGNC:HGNC:10085 +6056 RNR5 MIM:180454|HGNC:HGNC:10086 +6059 ABCE1 MIM:601213|HGNC:HGNC:69|Ensembl:ENSG00000164163|Vega:OTTHUMG00000161478 +6060 RNU1-4 MIM:180680|HGNC:HGNC:10128|Ensembl:ENSG00000207389 +6063 RNVU1-11 HGNC:HGNC:10134 +6066 RNU2-1 MIM:180690|HGNC:HGNC:10142|Ensembl:ENSG00000274585 +6068 SNORD3P1 HGNC:HGNC:10175 +6069 RNU4-7P HGNC:HGNC:10194 +6070 RNU4-8P HGNC:HGNC:10195 +6071 RNU6V HGNC:HGNC:10230 +6072 RNU7-68P HGNC:HGNC:10236 +6073 RNU7-86P HGNC:HGNC:10237 +6074 RNU7-24P HGNC:HGNC:34120 +6075 RNU7-55P HGNC:HGNC:10239 +6076 SNORD13P1 HGNC:HGNC:10110 +6077 SNORD13P2 HGNC:HGNC:10111 +6078 SNORD13P3 HGNC:HGNC:10112 +6079 SNORD15A MIM:600455|HGNC:HGNC:10114|Ensembl:ENSG00000206941 +6080 SNORA73A MIM:180645|HGNC:HGNC:10115|Ensembl:ENSG00000274266 +6082 SNORD20 MIM:604012|HGNC:HGNC:10143|Ensembl:ENSG00000207280 +6083 SNORD21 MIM:603635|HGNC:HGNC:10144|Ensembl:ENSG00000206680 +6084 RNY1 MIM:601821|HGNC:HGNC:10242|Ensembl:ENSG00000201098 +6085 RNY3 MIM:601822|HGNC:HGNC:10243|Ensembl:ENSG00000202354 +6086 RNY4 MIM:601823|HGNC:HGNC:10244|Ensembl:ENSG00000252316 +6087 RNY4P1 HGNC:HGNC:10245 +6088 RNY4P2 HGNC:HGNC:10246 +6089 RNY4P3 HGNC:HGNC:10247 +6090 RNY5 MIM:601824|HGNC:HGNC:10248 +6091 ROBO1 MIM:602430|HGNC:HGNC:10249|Ensembl:ENSG00000169855|Vega:OTTHUMG00000158843 +6092 ROBO2 MIM:602431|HGNC:HGNC:10250|Ensembl:ENSG00000185008|Vega:OTTHUMG00000158935 +6093 ROCK1 MIM:601702|HGNC:HGNC:10251|Ensembl:ENSG00000067900|Vega:OTTHUMG00000131723 +6094 ROM1 MIM:180721|HGNC:HGNC:10254|Ensembl:ENSG00000149489|Vega:OTTHUMG00000167528 +6095 RORA MIM:600825|HGNC:HGNC:10258|Ensembl:ENSG00000069667|Vega:OTTHUMG00000132769 +6096 RORB MIM:601972|HGNC:HGNC:10259|Ensembl:ENSG00000198963|Vega:OTTHUMG00000020026 +6097 RORC MIM:602943|HGNC:HGNC:10260|Ensembl:ENSG00000143365|Vega:OTTHUMG00000013053 +6098 ROS1 MIM:165020|HGNC:HGNC:10261|Ensembl:ENSG00000047936|Vega:OTTHUMG00000016188 +6100 RP9 MIM:607331|HGNC:HGNC:10288|Ensembl:ENSG00000164610|Vega:OTTHUMG00000152988 +6101 RP1 MIM:603937|HGNC:HGNC:10263|Ensembl:ENSG00000104237|Vega:OTTHUMG00000164379 +6102 RP2 MIM:300757|HGNC:HGNC:10274|Ensembl:ENSG00000102218|Vega:OTTHUMG00000021430 +6103 RPGR MIM:312610|HGNC:HGNC:10295|Ensembl:ENSG00000156313|Vega:OTTHUMG00000021361 +6104 RP6 MIM:312612|HGNC:HGNC:10286 +6114 RP22 MIM:602594|HGNC:HGNC:10276 +6116 RP24 MIM:300155|HGNC:HGNC:10278 +6117 RPA1 MIM:179835|HGNC:HGNC:10289|Ensembl:ENSG00000132383|Vega:OTTHUMG00000090579 +6118 RPA2 MIM:179836|HGNC:HGNC:10290|Ensembl:ENSG00000117748|Vega:OTTHUMG00000003915 +6119 RPA3 MIM:179837|HGNC:HGNC:10291|Ensembl:ENSG00000106399|Vega:OTTHUMG00000023748 +6120 RPE MIM:180480|HGNC:HGNC:10293|Ensembl:ENSG00000197713|Vega:OTTHUMG00000154690 +6121 RPE65 MIM:180069|HGNC:HGNC:10294|Ensembl:ENSG00000116745|Vega:OTTHUMG00000009208 +6122 RPL3 MIM:604163|HGNC:HGNC:10332|Ensembl:ENSG00000100316|Vega:OTTHUMG00000151079 +6123 RPL3L MIM:617416|HGNC:HGNC:10351|Ensembl:ENSG00000140986|Vega:OTTHUMG00000128685 +6124 RPL4 MIM:180479|HGNC:HGNC:10353|Ensembl:ENSG00000174444|Vega:OTTHUMG00000133193 +6125 RPL5 MIM:603634|HGNC:HGNC:10360|Ensembl:ENSG00000122406|Vega:OTTHUMG00000010899 +6126 RPL9P7 HGNC:HGNC:30335 +6128 RPL6 MIM:603703|HGNC:HGNC:10362|Ensembl:ENSG00000089009|Vega:OTTHUMG00000169685 +6129 RPL7 MIM:604166|HGNC:HGNC:10363|Ensembl:ENSG00000147604|Vega:OTTHUMG00000134312 +6130 RPL7A MIM:185640|HGNC:HGNC:10364|Ensembl:ENSG00000148303|Vega:OTTHUMG00000020864 +6132 RPL8 MIM:604177|HGNC:HGNC:10368|Ensembl:ENSG00000161016|Vega:OTTHUMG00000165249 +6133 RPL9 MIM:603686|HGNC:HGNC:10369|Ensembl:ENSG00000163682|Vega:OTTHUMG00000099367 +6134 RPL10 MIM:312173|HGNC:HGNC:10298|Ensembl:ENSG00000147403|Vega:OTTHUMG00000033189 +6135 RPL11 MIM:604175|HGNC:HGNC:10301|Ensembl:ENSG00000142676|Vega:OTTHUMG00000002926 +6136 RPL12 MIM:180475|HGNC:HGNC:10302|Ensembl:ENSG00000197958|Vega:OTTHUMG00000020704 +6137 RPL13 MIM:113703|HGNC:HGNC:10303|Ensembl:ENSG00000167526|Vega:OTTHUMG00000133770 +6138 RPL15 MIM:604174|HGNC:HGNC:10306|Ensembl:ENSG00000174748|Vega:OTTHUMG00000130485 +6139 RPL17 MIM:603661|HGNC:HGNC:10307|Ensembl:ENSG00000215472|Ensembl:ENSG00000265681|Vega:OTTHUMG00000179680|Vega:OTTHUMG00000179689 +6141 RPL18 MIM:604179|HGNC:HGNC:10310|Ensembl:ENSG00000063177|Vega:OTTHUMG00000169760 +6142 RPL18A MIM:604178|HGNC:HGNC:10311|Ensembl:ENSG00000105640|Vega:OTTHUMG00000183445 +6143 RPL19 MIM:180466|HGNC:HGNC:10312|Ensembl:ENSG00000108298|Vega:OTTHUMG00000178979 +6144 RPL21 MIM:603636|HGNC:HGNC:10313|Ensembl:ENSG00000122026|Vega:OTTHUMG00000016630 +6145 RPL21P1 MIM:603416|HGNC:HGNC:10314 +6146 RPL22 MIM:180474|HGNC:HGNC:10315|Ensembl:ENSG00000116251|Vega:OTTHUMG00000000953 +6147 RPL23A MIM:602326|HGNC:HGNC:10317|Ensembl:ENSG00000198242|Vega:OTTHUMG00000132684 +6148 RPL23AP1 HGNC:HGNC:10318 +6150 MRPL23 MIM:600789|HGNC:HGNC:10322|Ensembl:ENSG00000214026|Vega:OTTHUMG00000012476 +6152 RPL24 MIM:604180|HGNC:HGNC:10325|Ensembl:ENSG00000114391|Vega:OTTHUMG00000159146 +6154 RPL26 MIM:603704|HGNC:HGNC:10327|Ensembl:ENSG00000161970|Vega:OTTHUMG00000108191 +6155 RPL27 MIM:607526|HGNC:HGNC:10328|Ensembl:ENSG00000131469|Vega:OTTHUMG00000180660 +6156 RPL30 MIM:180467|HGNC:HGNC:10333|Ensembl:ENSG00000156482|Vega:OTTHUMG00000164796 +6157 RPL27A MIM:603637|HGNC:HGNC:10329|Ensembl:ENSG00000166441|Vega:OTTHUMG00000165834 +6158 RPL28 MIM:603638|HGNC:HGNC:10330|Ensembl:ENSG00000108107|Vega:OTTHUMG00000171991 +6159 RPL29 MIM:601832|HGNC:HGNC:10331|Ensembl:ENSG00000162244|Vega:OTTHUMG00000155262 +6160 RPL31 MIM:617415|HGNC:HGNC:10334|Ensembl:ENSG00000071082|Vega:OTTHUMG00000130687 +6161 RPL32 HGNC:HGNC:10336|Ensembl:ENSG00000144713|Vega:OTTHUMG00000129804 +6163 RPL32P1 HGNC:HGNC:10339 +6164 RPL34 MIM:616862|HGNC:HGNC:10340|Ensembl:ENSG00000109475|Vega:OTTHUMG00000131839 +6165 RPL35A MIM:180468|HGNC:HGNC:10345|Ensembl:ENSG00000182899|Vega:OTTHUMG00000155386 +6166 RPL36AL MIM:180469|HGNC:HGNC:10346|Ensembl:ENSG00000165502|Vega:OTTHUMG00000152330 +6167 RPL37 MIM:604181|HGNC:HGNC:10347|Ensembl:ENSG00000145592|Vega:OTTHUMG00000094774 +6168 RPL37A MIM:613314|HGNC:HGNC:10348|Ensembl:ENSG00000197756|Vega:OTTHUMG00000133052 +6169 RPL38 MIM:604182|HGNC:HGNC:10349|Ensembl:ENSG00000172809|Vega:OTTHUMG00000166016 +6170 RPL39 MIM:300899|HGNC:HGNC:10350|Ensembl:ENSG00000198918|Vega:OTTHUMG00000022278 +6171 RPL41 MIM:613315|HGNC:HGNC:10354|Ensembl:ENSG00000229117|Vega:OTTHUMG00000170183 +6172 RPL41P5 HGNC:HGNC:10355 +6173 RPL36A MIM:300902|HGNC:HGNC:10359|Ensembl:ENSG00000241343|Vega:OTTHUMG00000022027 +6174 RPL7P1 HGNC:HGNC:10367 +6175 RPLP0 MIM:180510|HGNC:HGNC:10371|Ensembl:ENSG00000089157|Vega:OTTHUMG00000169317 +6176 RPLP1 MIM:180520|HGNC:HGNC:10372|Ensembl:ENSG00000137818|Vega:OTTHUMG00000172087 +6181 RPLP2 MIM:180530|HGNC:HGNC:10377|Ensembl:ENSG00000177600|Vega:OTTHUMG00000133317 +6182 MRPL12 MIM:602375|HGNC:HGNC:10378|Ensembl:ENSG00000262814|Vega:OTTHUMG00000178171 +6183 MRPS12 MIM:603021|HGNC:HGNC:10380|Ensembl:ENSG00000128626|Vega:OTTHUMG00000182692 +6184 RPN1 MIM:180470|HGNC:HGNC:10381|Ensembl:ENSG00000163902|Vega:OTTHUMG00000159691 +6185 RPN2 MIM:180490|HGNC:HGNC:10382|Ensembl:ENSG00000118705|Vega:OTTHUMG00000032409 +6187 RPS2 MIM:603624|HGNC:HGNC:10404|Ensembl:ENSG00000140988|Vega:OTTHUMG00000128708 +6188 RPS3 MIM:600454|HGNC:HGNC:10420|Ensembl:ENSG00000149273|Vega:OTTHUMG00000165448 +6189 RPS3A MIM:180478|HGNC:HGNC:10421|Ensembl:ENSG00000145425|Vega:OTTHUMG00000161445 +6191 RPS4X MIM:312760|HGNC:HGNC:10424|Ensembl:ENSG00000198034|Vega:OTTHUMG00000021813 +6192 RPS4Y1 MIM:470000|HGNC:HGNC:10425|Ensembl:ENSG00000129824|Vega:OTTHUMG00000036152 +6193 RPS5 MIM:603630|HGNC:HGNC:10426|Ensembl:ENSG00000083845|Vega:OTTHUMG00000183530 +6194 RPS6 MIM:180460|HGNC:HGNC:10429|Ensembl:ENSG00000137154|Vega:OTTHUMG00000019642 +6195 RPS6KA1 MIM:601684|HGNC:HGNC:10430|Ensembl:ENSG00000117676|Vega:OTTHUMG00000004003 +6196 RPS6KA2 MIM:601685|HGNC:HGNC:10431|Ensembl:ENSG00000071242|Vega:OTTHUMG00000016007 +6197 RPS6KA3 MIM:300075|HGNC:HGNC:10432|Ensembl:ENSG00000177189|Vega:OTTHUMG00000021231 +6198 RPS6KB1 MIM:608938|HGNC:HGNC:10436|Ensembl:ENSG00000108443|Vega:OTTHUMG00000150642 +6199 RPS6KB2 MIM:608939|HGNC:HGNC:10437|Ensembl:ENSG00000175634|Vega:OTTHUMG00000167673 +6200 RPS6KB3 HGNC:HGNC:10438 +6201 RPS7 MIM:603658|HGNC:HGNC:10440|Ensembl:ENSG00000171863|Vega:OTTHUMG00000090305 +6202 RPS8 MIM:600357|HGNC:HGNC:10441|Ensembl:ENSG00000142937|Vega:OTTHUMG00000008494 +6203 RPS9 MIM:603631|HGNC:HGNC:10442|Ensembl:ENSG00000170889|Vega:OTTHUMG00000066618 +6204 RPS10 MIM:603632|HGNC:HGNC:10383|Ensembl:ENSG00000124614|Vega:OTTHUMG00000014546 +6205 RPS11 MIM:180471|HGNC:HGNC:10384|Ensembl:ENSG00000142534|Vega:OTTHUMG00000183156 +6206 RPS12 MIM:603660|HGNC:HGNC:10385|Ensembl:ENSG00000112306|Vega:OTTHUMG00000015593 +6207 RPS13 MIM:180476|HGNC:HGNC:10386|Ensembl:ENSG00000110700|Vega:OTTHUMG00000165988 +6208 RPS14 MIM:130620|HGNC:HGNC:10387|Ensembl:ENSG00000164587|Vega:OTTHUMG00000130080 +6209 RPS15 MIM:180535|HGNC:HGNC:10388|Ensembl:ENSG00000115268|Vega:OTTHUMG00000140099 +6210 RPS15A MIM:603674|HGNC:HGNC:10389|Ensembl:ENSG00000134419|Vega:OTTHUMG00000131365 +6217 RPS16 MIM:603675|HGNC:HGNC:10396|Ensembl:ENSG00000105193|Vega:OTTHUMG00000182972 +6218 RPS17 MIM:180472|HGNC:HGNC:10397|Ensembl:ENSG00000182774|Vega:OTTHUMG00000147355 +6219 RPS17P2 HGNC:HGNC:10398 +6222 RPS18 MIM:180473|HGNC:HGNC:10401|Ensembl:ENSG00000231500|Vega:OTTHUMG00000031053 +6223 RPS19 MIM:603474|HGNC:HGNC:10402|Ensembl:ENSG00000105372|Vega:OTTHUMG00000182676 +6224 RPS20 MIM:603682|HGNC:HGNC:10405|Ensembl:ENSG00000008988|Vega:OTTHUMG00000164297 +6225 RPS20P3 MIM:180463|HGNC:HGNC:10406 +6226 RPS20P4 MIM:180464|HGNC:HGNC:10407 +6227 RPS21 MIM:180477|HGNC:HGNC:10409|Ensembl:ENSG00000171858|Vega:OTTHUMG00000032915 +6228 RPS23 MIM:603683|HGNC:HGNC:10410|Ensembl:ENSG00000186468|Vega:OTTHUMG00000162557 +6229 RPS24 MIM:602412|HGNC:HGNC:10411|Ensembl:ENSG00000138326|Vega:OTTHUMG00000018549 +6230 RPS25 MIM:180465|HGNC:HGNC:10413|Ensembl:ENSG00000118181|Vega:OTTHUMG00000166350 +6231 RPS26 MIM:603701|HGNC:HGNC:10414|Ensembl:ENSG00000197728|Vega:OTTHUMG00000170139 +6232 RPS27 MIM:603702|HGNC:HGNC:10416|Ensembl:ENSG00000177954|Vega:OTTHUMG00000036591 +6233 RPS27A MIM:191343|HGNC:HGNC:10417|Ensembl:ENSG00000143947|Vega:OTTHUMG00000151919 +6234 RPS28 MIM:603685|HGNC:HGNC:10418|Ensembl:ENSG00000233927|Vega:OTTHUMG00000182460 +6235 RPS29 MIM:603633|HGNC:HGNC:10419|Ensembl:ENSG00000213741|Vega:OTTHUMG00000140272 +6236 RRAD MIM:179503|HGNC:HGNC:10446|Ensembl:ENSG00000166592|Vega:OTTHUMG00000137511 +6237 RRAS MIM:165090|HGNC:HGNC:10447|Ensembl:ENSG00000126458|Vega:OTTHUMG00000183247 +6238 RRBP1 MIM:601418|HGNC:HGNC:10448|Ensembl:ENSG00000125844|Vega:OTTHUMG00000031945 +6239 RREB1 MIM:602209|HGNC:HGNC:10449|Ensembl:ENSG00000124782|Vega:OTTHUMG00000014201 +6240 RRM1 MIM:180410|HGNC:HGNC:10451|Ensembl:ENSG00000167325|Vega:OTTHUMG00000133361 +6241 RRM2 MIM:180390|HGNC:HGNC:10452|Ensembl:ENSG00000171848|Vega:OTTHUMG00000090449 +6242 RTKN MIM:602288|HGNC:HGNC:10466|Ensembl:ENSG00000114993|Vega:OTTHUMG00000129955 +6244 RRM2P2 HGNC:HGNC:10454 +6246 RRM2P4 HGNC:HGNC:10456 +6247 RS1 MIM:300839|HGNC:HGNC:10457|Ensembl:ENSG00000102104|Vega:OTTHUMG00000021216 +6248 RSC1A1 MIM:601966|HGNC:HGNC:10458|Ensembl:ENSG00000215695|Vega:OTTHUMG00000067830 +6249 CLIP1 MIM:179838|HGNC:HGNC:10461|Ensembl:ENSG00000130779|Vega:OTTHUMG00000168922 +6251 RSU1 MIM:179555|HGNC:HGNC:10464|Ensembl:ENSG00000148484|Vega:OTTHUMG00000017740 +6252 RTN1 MIM:600865|HGNC:HGNC:10467|Ensembl:ENSG00000139970|Vega:OTTHUMG00000028947 +6253 RTN2 MIM:603183|HGNC:HGNC:10468|Ensembl:ENSG00000125744|Vega:OTTHUMG00000182123 +6256 RXRA MIM:180245|HGNC:HGNC:10477|Ensembl:ENSG00000186350|Vega:OTTHUMG00000020887 +6257 RXRB MIM:180246|HGNC:HGNC:10478|Ensembl:ENSG00000204231|Vega:OTTHUMG00000031298 +6258 RXRG MIM:180247|HGNC:HGNC:10479|Ensembl:ENSG00000143171|Vega:OTTHUMG00000034626 +6259 RYK MIM:600524|HGNC:HGNC:10481|Ensembl:ENSG00000163785|Vega:OTTHUMG00000159750 +6260 RYKP1 HGNC:HGNC:10482 +6261 RYR1 MIM:180901|HGNC:HGNC:10483|Ensembl:ENSG00000196218|Vega:OTTHUMG00000182403 +6262 RYR2 MIM:180902|HGNC:HGNC:10484|Ensembl:ENSG00000198626|Vega:OTTHUMG00000039543 +6263 RYR3 MIM:180903|HGNC:HGNC:10485|Ensembl:ENSG00000198838|Vega:OTTHUMG00000172253 +6264 S7 HGNC:HGNC:10509 +6267 S11 HGNC:HGNC:10505 +6268 S12 HGNC:HGNC:10506 +6271 S100A1 MIM:176940|HGNC:HGNC:10486|Ensembl:ENSG00000160678|Vega:OTTHUMG00000037041 +6272 SORT1 MIM:602458|HGNC:HGNC:11186|Ensembl:ENSG00000134243|Vega:OTTHUMG00000011999 +6273 S100A2 MIM:176993|HGNC:HGNC:10492|Ensembl:ENSG00000196754|Vega:OTTHUMG00000035031 +6274 S100A3 MIM:176992|HGNC:HGNC:10493|Ensembl:ENSG00000188015|Vega:OTTHUMG00000013550 +6275 S100A4 MIM:114210|HGNC:HGNC:10494|Ensembl:ENSG00000196154|Vega:OTTHUMG00000013546 +6276 S100A5 MIM:176991|HGNC:HGNC:10495|Ensembl:ENSG00000196420|Vega:OTTHUMG00000013547 +6277 S100A6 MIM:114110|HGNC:HGNC:10496|Ensembl:ENSG00000197956|Vega:OTTHUMG00000013549 +6278 S100A7 MIM:600353|HGNC:HGNC:10497|Ensembl:ENSG00000143556|Vega:OTTHUMG00000013123 +6279 S100A8 MIM:123885|HGNC:HGNC:10498|Ensembl:ENSG00000143546|Vega:OTTHUMG00000013124 +6280 S100A9 MIM:123886|HGNC:HGNC:10499|Ensembl:ENSG00000163220|Vega:OTTHUMG00000013125 +6281 S100A10 MIM:114085|HGNC:HGNC:10487|Ensembl:ENSG00000197747|Vega:OTTHUMG00000013068 +6282 S100A11 MIM:603114|HGNC:HGNC:10488|Ensembl:ENSG00000163191|Vega:OTTHUMG00000013069 +6283 S100A12 MIM:603112|HGNC:HGNC:10489|Ensembl:ENSG00000163221|Vega:OTTHUMG00000013127 +6284 S100A13 MIM:601989|HGNC:HGNC:10490|Ensembl:ENSG00000189171|Vega:OTTHUMG00000036641 +6285 S100B MIM:176990|HGNC:HGNC:10500|Ensembl:ENSG00000160307|Vega:OTTHUMG00000090715 +6286 S100P MIM:600614|HGNC:HGNC:10504|Ensembl:ENSG00000163993|Vega:OTTHUMG00000090491 +6287 SAA@ HGNC:HGNC:10512 +6288 SAA1 MIM:104750|HGNC:HGNC:10513|Ensembl:ENSG00000173432|Vega:OTTHUMG00000166147 +6289 SAA2 MIM:104751|HGNC:HGNC:10514|Ensembl:ENSG00000134339|Vega:OTTHUMG00000166484 +6290 SAA3P HGNC:HGNC:10515|Ensembl:ENSG00000166787 +6291 SAA4 MIM:104752|HGNC:HGNC:10516|Ensembl:ENSG00000148965|Vega:OTTHUMG00000166483 +6293 VPS52 MIM:603443|HGNC:HGNC:10518|Ensembl:ENSG00000223501|Vega:OTTHUMG00000031276 +6294 SAFB MIM:602895|HGNC:HGNC:10520|Ensembl:ENSG00000160633|Vega:OTTHUMG00000180502 +6295 SAG MIM:181031|HGNC:HGNC:10521|Ensembl:ENSG00000130561|Vega:OTTHUMG00000153213 +6296 ACSM3 MIM:145505|HGNC:HGNC:10522|Ensembl:ENSG00000005187|Vega:OTTHUMG00000131552 +6297 SALL2 MIM:602219|HGNC:HGNC:10526|Ensembl:ENSG00000165821|Vega:OTTHUMG00000168826 +6298 SAI1 MIM:154280|HGNC:HGNC:10523 +6299 SALL1 MIM:602218|HGNC:HGNC:10524|Ensembl:ENSG00000103449|Vega:OTTHUMG00000133176 +6300 MAPK12 MIM:602399|HGNC:HGNC:6874|Ensembl:ENSG00000188130|Vega:OTTHUMG00000030145 +6301 SARS MIM:607529|HGNC:HGNC:10537|Ensembl:ENSG00000031698|Vega:OTTHUMG00000011726 +6302 TSPAN31 MIM:181035|HGNC:HGNC:10539|Ensembl:ENSG00000135452|Vega:OTTHUMG00000170381 +6303 SAT1 MIM:313020|HGNC:HGNC:10540|Ensembl:ENSG00000130066|Vega:OTTHUMG00000021256 +6304 SATB1 MIM:602075|HGNC:HGNC:10541|Ensembl:ENSG00000182568|Vega:OTTHUMG00000129890 +6305 SBF1 MIM:603560|HGNC:HGNC:10542|Ensembl:ENSG00000100241|Vega:OTTHUMG00000150204 +6307 MSMO1 MIM:607545|HGNC:HGNC:10545|Ensembl:ENSG00000052802|Vega:OTTHUMG00000161126 +6308 SC4MOP HGNC:HGNC:10546 +6309 SC5D MIM:602286|HGNC:HGNC:10547|Ensembl:ENSG00000109929|Vega:OTTHUMG00000166068 +6310 ATXN1 MIM:601556|HGNC:HGNC:10548|Ensembl:ENSG00000124788|Vega:OTTHUMG00000014303 +6311 ATXN2 MIM:601517|HGNC:HGNC:10555|Ensembl:ENSG00000204842|Vega:OTTHUMG00000133475 +6314 ATXN7 MIM:607640|HGNC:HGNC:10560|Ensembl:ENSG00000163635|Vega:OTTHUMG00000158763 +6315 ATXN8OS MIM:603680|HGNC:HGNC:10561 +6317 SERPINB3 MIM:600517|HGNC:HGNC:10569|Ensembl:ENSG00000057149|Vega:OTTHUMG00000060403 +6318 SERPINB4 MIM:600518|HGNC:HGNC:10570|Ensembl:ENSG00000206073|Vega:OTTHUMG00000060405 +6319 SCD MIM:604031|HGNC:HGNC:10571|Ensembl:ENSG00000099194|Vega:OTTHUMG00000018906 +6320 CLEC11A MIM:604713|HGNC:HGNC:10576|Ensembl:ENSG00000105472|Vega:OTTHUMG00000182866 +6322 SCML1 MIM:300227|HGNC:HGNC:10580|Ensembl:ENSG00000047634|Vega:OTTHUMG00000021206 +6323 SCN1A MIM:182389|HGNC:HGNC:10585|Ensembl:ENSG00000144285|Vega:OTTHUMG00000044173 +6324 SCN1B MIM:600235|HGNC:HGNC:10586|Ensembl:ENSG00000105711|Vega:OTTHUMG00000182472 +6326 SCN2A MIM:182390|HGNC:HGNC:10588|Ensembl:ENSG00000136531|Vega:OTTHUMG00000044172 +6327 SCN2B MIM:601327|HGNC:HGNC:10589|Ensembl:ENSG00000149575|Vega:OTTHUMG00000048248 +6328 SCN3A MIM:182391|HGNC:HGNC:10590|Ensembl:ENSG00000153253|Vega:OTTHUMG00000044171 +6329 SCN4A MIM:603967|HGNC:HGNC:10591|Ensembl:ENSG00000007314|Vega:OTTHUMG00000179046 +6330 SCN4B MIM:608256|HGNC:HGNC:10592|Ensembl:ENSG00000177098|Vega:OTTHUMG00000166994 +6331 SCN5A MIM:600163|HGNC:HGNC:10593|Ensembl:ENSG00000183873|Vega:OTTHUMG00000156166 +6332 SCN7A MIM:182392|HGNC:HGNC:10594|Ensembl:ENSG00000136546|Vega:OTTHUMG00000154078 +6334 SCN8A MIM:600702|HGNC:HGNC:10596|Ensembl:ENSG00000196876|Vega:OTTHUMG00000169490 +6335 SCN9A MIM:603415|HGNC:HGNC:10597|Ensembl:ENSG00000169432|Vega:OTTHUMG00000154044 +6336 SCN10A MIM:604427|HGNC:HGNC:10582|Ensembl:ENSG00000185313|Vega:OTTHUMG00000048245 +6337 SCNN1A MIM:600228|HGNC:HGNC:10599|Ensembl:ENSG00000111319|Vega:OTTHUMG00000168268 +6338 SCNN1B MIM:600760|HGNC:HGNC:10600|Ensembl:ENSG00000168447|Vega:OTTHUMG00000131608 +6339 SCNN1D MIM:601328|HGNC:HGNC:10601|Ensembl:ENSG00000162572|Vega:OTTHUMG00000002081 +6340 SCNN1G MIM:600761|HGNC:HGNC:10602|Ensembl:ENSG00000166828|Vega:OTTHUMG00000131609 +6341 SCO1 MIM:603644|HGNC:HGNC:10603|Ensembl:ENSG00000133028|Vega:OTTHUMG00000130364 +6342 SCP2 MIM:184755|HGNC:HGNC:10606|Ensembl:ENSG00000116171|Vega:OTTHUMG00000008936 +6343 SCT MIM:182099|HGNC:HGNC:10607|Ensembl:ENSG00000070031|Vega:OTTHUMG00000133313 +6344 SCTR MIM:182098|HGNC:HGNC:10608|Ensembl:ENSG00000080293|Vega:OTTHUMG00000131407 +6345 SRL MIM:604992|HGNC:HGNC:11295|Ensembl:ENSG00000185739|Vega:OTTHUMG00000177617 +6346 CCL1 MIM:182281|HGNC:HGNC:10609|Ensembl:ENSG00000108702|Vega:OTTHUMG00000132888 +6347 CCL2 MIM:158105|HGNC:HGNC:10618|Ensembl:ENSG00000108691|Vega:OTTHUMG00000132887 +6348 CCL3 MIM:182283|HGNC:HGNC:10627|Ensembl:ENSG00000277632|Vega:OTTHUMG00000188413 +6349 CCL3L1 MIM:601395|HGNC:HGNC:10628 +6351 CCL4 MIM:182284|HGNC:HGNC:10630|Ensembl:ENSG00000275302|Vega:OTTHUMG00000188414 +6352 CCL5 MIM:187011|HGNC:HGNC:10632|Ensembl:ENSG00000271503|Vega:OTTHUMG00000188396 +6354 CCL7 MIM:158106|HGNC:HGNC:10634|Ensembl:ENSG00000108688|Vega:OTTHUMG00000132889 +6355 CCL8 MIM:602283|HGNC:HGNC:10635|Ensembl:ENSG00000108700|Vega:OTTHUMG00000132883 +6356 CCL11 MIM:601156|HGNC:HGNC:10610|Ensembl:ENSG00000172156|Vega:OTTHUMG00000132884 +6357 CCL13 MIM:601391|HGNC:HGNC:10611|Ensembl:ENSG00000181374|Vega:OTTHUMG00000132890 +6358 CCL14 MIM:601392|HGNC:HGNC:10612|Ensembl:ENSG00000276409|Vega:OTTHUMG00000188403 +6359 CCL15 MIM:601393|HGNC:HGNC:10613|Ensembl:ENSG00000275688|Ensembl:ENSG00000275718|Vega:OTTHUMG00000188405|Vega:OTTHUMG00000188406 +6360 CCL16 MIM:601394|HGNC:HGNC:10614|Ensembl:ENSG00000275152|Vega:OTTHUMG00000188402 +6361 CCL17 MIM:601520|HGNC:HGNC:10615|Ensembl:ENSG00000102970|Vega:OTTHUMG00000133468 +6362 CCL18 MIM:603757|HGNC:HGNC:10616|Ensembl:ENSG00000275385|Vega:OTTHUMG00000188410 +6363 CCL19 MIM:602227|HGNC:HGNC:10617|Ensembl:ENSG00000172724|Vega:OTTHUMG00000019833 +6364 CCL20 MIM:601960|HGNC:HGNC:10619|Ensembl:ENSG00000115009|Vega:OTTHUMG00000133189 +6365 SCZD3 MIM:600511|HGNC:HGNC:10651 +6366 CCL21 MIM:602737|HGNC:HGNC:10620|Ensembl:ENSG00000137077|Vega:OTTHUMG00000019838 +6367 CCL22 MIM:602957|HGNC:HGNC:10621|Ensembl:ENSG00000102962|Vega:OTTHUMG00000133454 +6368 CCL23 MIM:602494|HGNC:HGNC:10622|Ensembl:ENSG00000274736|Vega:OTTHUMG00000188409 +6369 CCL24 MIM:602495|HGNC:HGNC:10623|Ensembl:ENSG00000106178|Vega:OTTHUMG00000156635 +6370 CCL25 MIM:602565|HGNC:HGNC:10624|Ensembl:ENSG00000131142|Vega:OTTHUMG00000141287 +6372 CXCL6 MIM:138965|HGNC:HGNC:10643|Ensembl:ENSG00000124875|Vega:OTTHUMG00000130010 +6373 CXCL11 MIM:604852|HGNC:HGNC:10638|Ensembl:ENSG00000169248|Vega:OTTHUMG00000130101 +6374 CXCL5 MIM:600324|HGNC:HGNC:10642|Ensembl:ENSG00000163735|Vega:OTTHUMG00000160871 +6375 XCL1 MIM:600250|HGNC:HGNC:10645|Ensembl:ENSG00000143184|Vega:OTTHUMG00000034548 +6376 CX3CL1 MIM:601880|HGNC:HGNC:10647|Ensembl:ENSG00000006210|Vega:OTTHUMG00000133469 +6377 SCZD1 MIM:181510|HGNC:HGNC:10649 +6378 SCZD2 MIM:603342|HGNC:HGNC:10650 +6382 SDC1 MIM:186355|HGNC:HGNC:10658|Ensembl:ENSG00000115884|Vega:OTTHUMG00000090751 +6383 SDC2 MIM:142460|HGNC:HGNC:10659|Ensembl:ENSG00000169439|Vega:OTTHUMG00000164689 +6385 SDC4 MIM:600017|HGNC:HGNC:10661|Ensembl:ENSG00000124145|Vega:OTTHUMG00000033083 +6386 SDCBP MIM:602217|HGNC:HGNC:10662|Ensembl:ENSG00000137575|Vega:OTTHUMG00000164303 +6387 CXCL12 MIM:600835|HGNC:HGNC:10672|Ensembl:ENSG00000107562|Vega:OTTHUMG00000018054 +6388 SDF2 MIM:602934|HGNC:HGNC:10675|Ensembl:ENSG00000132581|Vega:OTTHUMG00000132681 +6389 SDHA MIM:600857|HGNC:HGNC:10680|Ensembl:ENSG00000073578|Vega:OTTHUMG00000090275 +6390 SDHB MIM:185470|HGNC:HGNC:10681|Ensembl:ENSG00000117118|Vega:OTTHUMG00000002289 +6391 SDHC MIM:602413|HGNC:HGNC:10682|Ensembl:ENSG00000143252|Vega:OTTHUMG00000034468 +6392 SDHD MIM:602690|HGNC:HGNC:10683|Ensembl:ENSG00000204370|Ensembl:ENSG00000255292|Vega:OTTHUMG00000166997 +6395 SEA MIM:165110|HGNC:HGNC:10695 +6396 SEC13 MIM:600152|HGNC:HGNC:10697|Ensembl:ENSG00000157020|Vega:OTTHUMG00000128671 +6397 SEC14L1 MIM:601504|HGNC:HGNC:10698|Ensembl:ENSG00000129657|Vega:OTTHUMG00000177311 +6398 SECTM1 MIM:602602|HGNC:HGNC:10707|Ensembl:ENSG00000141574|Vega:OTTHUMG00000178668 +6399 TRAPPC2 MIM:300202|HGNC:HGNC:23068|Ensembl:ENSG00000196459|Vega:OTTHUMG00000021157 +6400 SEL1L MIM:602329|HGNC:HGNC:10717|Ensembl:ENSG00000071537|Vega:OTTHUMG00000171419 +6401 SELE MIM:131210|HGNC:HGNC:10718|Ensembl:ENSG00000007908|Vega:OTTHUMG00000034851 +6402 SELL MIM:153240|HGNC:HGNC:10720|Ensembl:ENSG00000188404|Vega:OTTHUMG00000034809 +6403 SELP MIM:173610|HGNC:HGNC:10721|Ensembl:ENSG00000174175|Vega:OTTHUMG00000034685 +6404 SELPLG MIM:600738|HGNC:HGNC:10722|Ensembl:ENSG00000110876|Vega:OTTHUMG00000169411 +6405 SEMA3F MIM:601124|HGNC:HGNC:10728|Ensembl:ENSG00000001617|Vega:OTTHUMG00000156806 +6406 SEMG1 MIM:182140|HGNC:HGNC:10742|Ensembl:ENSG00000124233|Vega:OTTHUMG00000032565 +6407 SEMG2 MIM:182141|HGNC:HGNC:10743|Ensembl:ENSG00000124157|Vega:OTTHUMG00000032566 +6409 SEN2 HGNC:HGNC:10745 +6410 SEN3 HGNC:HGNC:10746 +6411 SEN6 HGNC:HGNC:10747 +6412 SEN6A HGNC:HGNC:10748 +6413 SEN6B HGNC:HGNC:10749 +6414 SELENOP MIM:601484|HGNC:HGNC:10751|Ensembl:ENSG00000250722|Vega:OTTHUMG00000162140 +6415 SELENOW MIM:603235|HGNC:HGNC:10752|Ensembl:ENSG00000178980|Vega:OTTHUMG00000183061 +6416 MAP2K4 MIM:601335|HGNC:HGNC:6844|Ensembl:ENSG00000065559|Vega:OTTHUMG00000178267 +6418 SET MIM:600960|HGNC:HGNC:10760|Ensembl:ENSG00000119335|Vega:OTTHUMG00000020755 +6419 SETMAR MIM:609834|HGNC:HGNC:10762|Ensembl:ENSG00000170364|Vega:OTTHUMG00000090265 +6420 SF MIM:111800 +6421 SFPQ MIM:605199|HGNC:HGNC:10774|Ensembl:ENSG00000116560|Vega:OTTHUMG00000004157 +6422 SFRP1 MIM:604156|HGNC:HGNC:10776|Ensembl:ENSG00000104332|Vega:OTTHUMG00000164074 +6423 SFRP2 MIM:604157|HGNC:HGNC:10777|Ensembl:ENSG00000145423|Vega:OTTHUMG00000161559 +6424 SFRP4 MIM:606570|HGNC:HGNC:10778|Ensembl:ENSG00000106483|Vega:OTTHUMG00000023026 +6425 SFRP5 MIM:604158|HGNC:HGNC:10779|Ensembl:ENSG00000120057|Vega:OTTHUMG00000018866 +6426 SRSF1 MIM:600812|HGNC:HGNC:10780|Ensembl:ENSG00000136450|Vega:OTTHUMG00000178781 +6427 SRSF2 MIM:600813|HGNC:HGNC:10783|Ensembl:ENSG00000161547|Vega:OTTHUMG00000177547 +6428 SRSF3 MIM:603364|HGNC:HGNC:10785|Ensembl:ENSG00000112081|Vega:OTTHUMG00000014599 +6429 SRSF4 MIM:601940|HGNC:HGNC:10786|Ensembl:ENSG00000116350|Vega:OTTHUMG00000003663 +6430 SRSF5 MIM:600914|HGNC:HGNC:10787|Ensembl:ENSG00000100650|Vega:OTTHUMG00000171235 +6431 SRSF6 MIM:601944|HGNC:HGNC:10788|Ensembl:ENSG00000124193|Vega:OTTHUMG00000032502 +6432 SRSF7 MIM:600572|HGNC:HGNC:10789|Ensembl:ENSG00000115875|Vega:OTTHUMG00000102076 +6433 SFSWAP MIM:601945|HGNC:HGNC:10790|Ensembl:ENSG00000061936|Vega:OTTHUMG00000168319 +6434 TRA2B MIM:602719|HGNC:HGNC:10781|Ensembl:ENSG00000136527|Vega:OTTHUMG00000156641 +6439 SFTPB MIM:178640|HGNC:HGNC:10801|Ensembl:ENSG00000168878|Vega:OTTHUMG00000130181 +6440 SFTPC MIM:178620|HGNC:HGNC:10802|Ensembl:ENSG00000168484|Vega:OTTHUMG00000163775 +6441 SFTPD MIM:178635|HGNC:HGNC:10803|Ensembl:ENSG00000133661|Vega:OTTHUMG00000018590 +6442 SGCA MIM:600119|HGNC:HGNC:10805|Ensembl:ENSG00000108823|Vega:OTTHUMG00000162024 +6443 SGCB MIM:600900|HGNC:HGNC:10806|Ensembl:ENSG00000163069|Vega:OTTHUMG00000128697 +6444 SGCD MIM:601411|HGNC:HGNC:10807|Ensembl:ENSG00000170624|Vega:OTTHUMG00000163445 +6445 SGCG MIM:608896|HGNC:HGNC:10809|Ensembl:ENSG00000102683|Vega:OTTHUMG00000016563 +6446 SGK1 MIM:602958|HGNC:HGNC:10810|Ensembl:ENSG00000118515|Vega:OTTHUMG00000015613 +6447 SCG5 MIM:173120|HGNC:HGNC:10816|Ensembl:ENSG00000166922|Vega:OTTHUMG00000159447 +6448 SGSH MIM:605270|HGNC:HGNC:10818|Ensembl:ENSG00000181523|Vega:OTTHUMG00000177569 +6449 SGTA MIM:603419|HGNC:HGNC:10819|Ensembl:ENSG00000104969|Vega:OTTHUMG00000180474 +6450 SH3BGR MIM:602230|HGNC:HGNC:10822|Ensembl:ENSG00000185437|Vega:OTTHUMG00000074113 +6451 SH3BGRL MIM:300190|HGNC:HGNC:10823|Ensembl:ENSG00000131171|Vega:OTTHUMG00000021910 +6452 SH3BP2 MIM:602104|HGNC:HGNC:10825|Ensembl:ENSG00000087266|Vega:OTTHUMG00000160801 +6453 ITSN1 MIM:602442|HGNC:HGNC:6183|Ensembl:ENSG00000205726|Vega:OTTHUMG00000065284 +6455 SH3GL1 MIM:601768|HGNC:HGNC:10830|Ensembl:ENSG00000141985|Vega:OTTHUMG00000181918 +6456 SH3GL2 MIM:604465|HGNC:HGNC:10831|Ensembl:ENSG00000107295|Vega:OTTHUMG00000019601 +6457 SH3GL3 MIM:603362|HGNC:HGNC:10832|Ensembl:ENSG00000140600|Vega:OTTHUMG00000147361 +6458 SH3GL1P1 HGNC:HGNC:10835 +6459 SH3GL1P2 HGNC:HGNC:10836 +6461 SHB MIM:600314|HGNC:HGNC:10838|Ensembl:ENSG00000107338|Vega:OTTHUMG00000019936 +6462 SHBG MIM:182205|HGNC:HGNC:10839|Ensembl:ENSG00000129214|Vega:OTTHUMG00000108153 +6463 SHFM2 MIM:313350|HGNC:HGNC:10846 +6464 SHC1 MIM:600560|HGNC:HGNC:10840|Ensembl:ENSG00000160691|Vega:OTTHUMG00000037295 +6465 SHC1P1 HGNC:HGNC:10841 +6466 SHC1P2 MIM:600739|HGNC:HGNC:10842 +6468 FBXW4 MIM:608071|HGNC:HGNC:10847|Ensembl:ENSG00000107829|Vega:OTTHUMG00000018938 +6469 SHH MIM:600725|HGNC:HGNC:10848|Ensembl:ENSG00000164690|Vega:OTTHUMG00000151349 +6470 SHMT1 MIM:182144|HGNC:HGNC:10850|Ensembl:ENSG00000176974|Vega:OTTHUMG00000059094 +6471 SHMT1P1 HGNC:HGNC:10851 +6472 SHMT2 MIM:138450|HGNC:HGNC:10852|Ensembl:ENSG00000182199|Vega:OTTHUMG00000171246 +6473 SHOX MIM:312865|MIM:400020|HGNC:HGNC:10853|Ensembl:ENSG00000185960|Vega:OTTHUMG00000021053 +6474 SHOX2 MIM:602504|HGNC:HGNC:10854|Ensembl:ENSG00000168779|Vega:OTTHUMG00000158755 +6476 SI MIM:609845|HGNC:HGNC:10856|Ensembl:ENSG00000090402|Vega:OTTHUMG00000158065 +6477 SIAH1 MIM:602212|HGNC:HGNC:10857|Ensembl:ENSG00000196470|Vega:OTTHUMG00000175417 +6478 SIAH2 MIM:602213|HGNC:HGNC:10858|Ensembl:ENSG00000181788|Vega:OTTHUMG00000159847 +6480 ST6GAL1 MIM:109675|HGNC:HGNC:10860|Ensembl:ENSG00000073849|Vega:OTTHUMG00000156500 +6482 ST3GAL1 MIM:607187|HGNC:HGNC:10862|Ensembl:ENSG00000008513|Vega:OTTHUMG00000164534 +6483 ST3GAL2 MIM:607188|HGNC:HGNC:10863|Ensembl:ENSG00000157350|Vega:OTTHUMG00000137580 +6484 ST3GAL4 MIM:104240|HGNC:HGNC:10864|Ensembl:ENSG00000110080|Vega:OTTHUMG00000165830 +6487 ST3GAL3 MIM:606494|HGNC:HGNC:10866|Ensembl:ENSG00000126091|Vega:OTTHUMG00000007561 +6489 ST8SIA1 MIM:601123|HGNC:HGNC:10869|Ensembl:ENSG00000111728|Vega:OTTHUMG00000169098 +6490 PMEL MIM:155550|HGNC:HGNC:10880|Ensembl:ENSG00000185664|Vega:OTTHUMG00000170573 +6491 STIL MIM:181590|HGNC:HGNC:10879|Ensembl:ENSG00000123473|Vega:OTTHUMG00000007851 +6492 SIM1 MIM:603128|HGNC:HGNC:10882|Ensembl:ENSG00000112246|Vega:OTTHUMG00000015275 +6493 SIM2 MIM:600892|HGNC:HGNC:10883|Ensembl:ENSG00000159263|Vega:OTTHUMG00000086637 +6494 SIPA1 MIM:602180|HGNC:HGNC:10885|Ensembl:ENSG00000213445|Vega:OTTHUMG00000166541 +6495 SIX1 MIM:601205|HGNC:HGNC:10887|Ensembl:ENSG00000126778|Vega:OTTHUMG00000140334 +6496 SIX3 MIM:603714|HGNC:HGNC:10889|Ensembl:ENSG00000138083|Vega:OTTHUMG00000152424 +6497 SKI MIM:164780|HGNC:HGNC:10896|Ensembl:ENSG00000157933|Vega:OTTHUMG00000001407 +6498 SKIL MIM:165340|HGNC:HGNC:10897|Ensembl:ENSG00000136603|Vega:OTTHUMG00000158831 +6499 SKIV2L MIM:600478|HGNC:HGNC:10898|Ensembl:ENSG00000204351|Vega:OTTHUMG00000031146 +6500 SKP1 MIM:601434|HGNC:HGNC:10899|Ensembl:ENSG00000113558|Vega:OTTHUMG00000129117 +6502 SKP2 MIM:601436|HGNC:HGNC:10901|Ensembl:ENSG00000145604|Vega:OTTHUMG00000131106 +6503 SLA MIM:601099|HGNC:HGNC:10902|Ensembl:ENSG00000155926|Vega:OTTHUMG00000164439 +6504 SLAMF1 MIM:603492|HGNC:HGNC:10903|Ensembl:ENSG00000117090|Vega:OTTHUMG00000024006 +6505 SLC1A1 MIM:133550|HGNC:HGNC:10939|Ensembl:ENSG00000106688|Vega:OTTHUMG00000019468 +6506 SLC1A2 MIM:600300|HGNC:HGNC:10940|Ensembl:ENSG00000110436|Vega:OTTHUMG00000044391 +6507 SLC1A3 MIM:600111|HGNC:HGNC:10941|Ensembl:ENSG00000079215|Vega:OTTHUMG00000090793 +6508 SLC4A3 MIM:106195|HGNC:HGNC:11029|Ensembl:ENSG00000114923|Vega:OTTHUMG00000059238 +6509 SLC1A4 MIM:600229|HGNC:HGNC:10942|Ensembl:ENSG00000115902|Vega:OTTHUMG00000129537 +6510 SLC1A5 MIM:109190|HGNC:HGNC:10943|Ensembl:ENSG00000105281|Vega:OTTHUMG00000183434 +6511 SLC1A6 MIM:600637|HGNC:HGNC:10944|Ensembl:ENSG00000105143|Vega:OTTHUMG00000183351 +6512 SLC1A7 MIM:604471|HGNC:HGNC:10945|Ensembl:ENSG00000162383|Vega:OTTHUMG00000008937 +6513 SLC2A1 MIM:138140|HGNC:HGNC:11005|Ensembl:ENSG00000117394|Vega:OTTHUMG00000007657 +6514 SLC2A2 MIM:138160|HGNC:HGNC:11006|Ensembl:ENSG00000163581|Vega:OTTHUMG00000158997 +6515 SLC2A3 MIM:138170|HGNC:HGNC:11007|Ensembl:ENSG00000059804|Vega:OTTHUMG00000133685 +6517 SLC2A4 MIM:138190|HGNC:HGNC:11009|Ensembl:ENSG00000181856|Vega:OTTHUMG00000102181 +6518 SLC2A5 MIM:138230|HGNC:HGNC:11010|Ensembl:ENSG00000142583|Vega:OTTHUMG00000001771 +6519 SLC3A1 MIM:104614|HGNC:HGNC:11025|Ensembl:ENSG00000138079|Vega:OTTHUMG00000128759 +6520 SLC3A2 MIM:158070|HGNC:HGNC:11026|Ensembl:ENSG00000168003|Vega:OTTHUMG00000074091 +6521 SLC4A1 MIM:109270|HGNC:HGNC:11027|Ensembl:ENSG00000004939|Vega:OTTHUMG00000156843 +6522 SLC4A2 MIM:109280|HGNC:HGNC:11028|Ensembl:ENSG00000164889|Vega:OTTHUMG00000158443 +6523 SLC5A1 MIM:182380|HGNC:HGNC:11036|Ensembl:ENSG00000100170|Vega:OTTHUMG00000030768 +6524 SLC5A2 MIM:182381|HGNC:HGNC:11037|Ensembl:ENSG00000140675|Vega:OTTHUMG00000176620 +6525 SMTN MIM:602127|HGNC:HGNC:11126|Ensembl:ENSG00000183963|Vega:OTTHUMG00000151203 +6526 SLC5A3 MIM:600444|HGNC:HGNC:11038|Ensembl:ENSG00000198743|Vega:OTTHUMG00000065821 +6527 SLC5A4 HGNC:HGNC:11039|Ensembl:ENSG00000100191|Vega:OTTHUMG00000150007 +6528 SLC5A5 MIM:601843|HGNC:HGNC:11040|Ensembl:ENSG00000105641|Vega:OTTHUMG00000183447 +6529 SLC6A1 MIM:137165|HGNC:HGNC:11042|Ensembl:ENSG00000157103|Vega:OTTHUMG00000044208 +6530 SLC6A2 MIM:163970|HGNC:HGNC:11048|Ensembl:ENSG00000103546|Vega:OTTHUMG00000133208 +6531 SLC6A3 MIM:126455|HGNC:HGNC:11049|Ensembl:ENSG00000142319|Vega:OTTHUMG00000131016 +6532 SLC6A4 MIM:182138|HGNC:HGNC:11050|Ensembl:ENSG00000108576|Vega:OTTHUMG00000132751 +6533 SLC6A6 MIM:186854|HGNC:HGNC:11052|Ensembl:ENSG00000131389|Vega:OTTHUMG00000155525 +6534 SLC6A7 MIM:606205|HGNC:HGNC:11054|Ensembl:ENSG00000011083|Vega:OTTHUMG00000130046 +6535 SLC6A8 MIM:300036|HGNC:HGNC:11055|Ensembl:ENSG00000130821|Vega:OTTHUMG00000024208 +6536 SLC6A9 MIM:601019|HGNC:HGNC:11056|Ensembl:ENSG00000196517|Vega:OTTHUMG00000008294 +6538 SLC6A11 MIM:607952|HGNC:HGNC:11044|Ensembl:ENSG00000132164|Vega:OTTHUMG00000129718 +6539 SLC6A12 MIM:603080|HGNC:HGNC:11045|Ensembl:ENSG00000111181|Vega:OTTHUMG00000090309 +6540 SLC6A13 MIM:615097|HGNC:HGNC:11046|Ensembl:ENSG00000010379|Vega:OTTHUMG00000168053 +6541 SLC7A1 MIM:104615|HGNC:HGNC:11057|Ensembl:ENSG00000139514|Vega:OTTHUMG00000016658 +6542 SLC7A2 MIM:601872|HGNC:HGNC:11060|Ensembl:ENSG00000003989|Vega:OTTHUMG00000130819 +6543 SLC8A2 MIM:601901|HGNC:HGNC:11069|Ensembl:ENSG00000118160|Vega:OTTHUMG00000183529 +6545 SLC7A4 MIM:603752|HGNC:HGNC:11062|Ensembl:ENSG00000099960|Vega:OTTHUMG00000150896 +6546 SLC8A1 MIM:182305|HGNC:HGNC:11068|Ensembl:ENSG00000183023|Vega:OTTHUMG00000102183 +6547 SLC8A3 MIM:607991|HGNC:HGNC:11070|Ensembl:ENSG00000100678|Vega:OTTHUMG00000152342 +6548 SLC9A1 MIM:107310|HGNC:HGNC:11071|Ensembl:ENSG00000090020|Vega:OTTHUMG00000004271 +6549 SLC9A2 MIM:600530|HGNC:HGNC:11072|Ensembl:ENSG00000115616|Vega:OTTHUMG00000130778 +6550 SLC9A3 MIM:182307|HGNC:HGNC:11073|Ensembl:ENSG00000066230|Vega:OTTHUMG00000090315 +6551 SLC9A3P1 HGNC:HGNC:11074 +6553 SLC9A5 MIM:600477|HGNC:HGNC:11078|Ensembl:ENSG00000135740|Vega:OTTHUMG00000172935 +6554 SLC10A1 MIM:182396|HGNC:HGNC:10905|Ensembl:ENSG00000100652|Vega:OTTHUMG00000171236 +6555 SLC10A2 MIM:601295|HGNC:HGNC:10906|Ensembl:ENSG00000125255|Vega:OTTHUMG00000017313 +6556 SLC11A1 MIM:600266|HGNC:HGNC:10907|Ensembl:ENSG00000018280|Vega:OTTHUMG00000086747 +6557 SLC12A1 MIM:600839|HGNC:HGNC:10910|Ensembl:ENSG00000074803|Vega:OTTHUMG00000131495 +6558 SLC12A2 MIM:600840|HGNC:HGNC:10911|Ensembl:ENSG00000064651|Vega:OTTHUMG00000128983 +6559 SLC12A3 MIM:600968|HGNC:HGNC:10912|Ensembl:ENSG00000070915|Vega:OTTHUMG00000133284 +6560 SLC12A4 MIM:604119|HGNC:HGNC:10913|Ensembl:ENSG00000124067|Vega:OTTHUMG00000137535 +6561 SLC13A1 MIM:606193|HGNC:HGNC:10916|Ensembl:ENSG00000081800|Vega:OTTHUMG00000157087 +6563 SLC14A1 MIM:613868|HGNC:HGNC:10918|Ensembl:ENSG00000141469|Vega:OTTHUMG00000132617 +6564 SLC15A1 MIM:600544|HGNC:HGNC:10920|Ensembl:ENSG00000088386|Vega:OTTHUMG00000017255 +6565 SLC15A2 MIM:602339|HGNC:HGNC:10921|Ensembl:ENSG00000163406|Vega:OTTHUMG00000159423 +6566 SLC16A1 MIM:600682|HGNC:HGNC:10922|Ensembl:ENSG00000155380|Vega:OTTHUMG00000012129 +6567 SLC16A2 MIM:300095|HGNC:HGNC:10923|Ensembl:ENSG00000147100|Vega:OTTHUMG00000021857 +6568 SLC17A1 MIM:182308|HGNC:HGNC:10929|Ensembl:ENSG00000124568|Vega:OTTHUMG00000016297 +6569 SLC34A1 MIM:182309|HGNC:HGNC:11019|Ensembl:ENSG00000131183|Vega:OTTHUMG00000130857 +6570 SLC18A1 MIM:193002|HGNC:HGNC:10934|Ensembl:ENSG00000036565|Vega:OTTHUMG00000097017 +6571 SLC18A2 MIM:193001|HGNC:HGNC:10935|Ensembl:ENSG00000165646|Vega:OTTHUMG00000019121 +6572 SLC18A3 MIM:600336|HGNC:HGNC:10936|Ensembl:ENSG00000187714|Vega:OTTHUMG00000018196 +6573 SLC19A1 MIM:600424|HGNC:HGNC:10937|Ensembl:ENSG00000173638|Vega:OTTHUMG00000090397 +6574 SLC20A1 MIM:137570|HGNC:HGNC:10946|Ensembl:ENSG00000144136|Vega:OTTHUMG00000131317 +6575 SLC20A2 MIM:158378|HGNC:HGNC:10947|Ensembl:ENSG00000168575|Vega:OTTHUMG00000164169 +6576 SLC25A1 MIM:190315|HGNC:HGNC:10979|Ensembl:ENSG00000100075|Vega:OTTHUMG00000150123 +6578 SLCO2A1 MIM:601460|HGNC:HGNC:10955|Ensembl:ENSG00000174640|Vega:OTTHUMG00000159745 +6579 SLCO1A2 MIM:602883|HGNC:HGNC:10956|Ensembl:ENSG00000084453|Vega:OTTHUMG00000156259 +6580 SLC22A1 MIM:602607|HGNC:HGNC:10963|Ensembl:ENSG00000175003|Vega:OTTHUMG00000015947 +6581 SLC22A3 MIM:604842|HGNC:HGNC:10967|Ensembl:ENSG00000146477|Vega:OTTHUMG00000015953 +6582 SLC22A2 MIM:602608|HGNC:HGNC:10966|Ensembl:ENSG00000112499|Vega:OTTHUMG00000015950 +6583 SLC22A4 MIM:604190|HGNC:HGNC:10968|Ensembl:ENSG00000197208|Vega:OTTHUMG00000059648 +6584 SLC22A5 MIM:603377|HGNC:HGNC:10969|Ensembl:ENSG00000197375|Vega:OTTHUMG00000059634 +6585 SLIT1 MIM:603742|HGNC:HGNC:11085|Ensembl:ENSG00000187122|Vega:OTTHUMG00000018843 +6586 SLIT3 MIM:603745|HGNC:HGNC:11087|Ensembl:ENSG00000184347|Vega:OTTHUMG00000130409 +6588 SLN MIM:602203|HGNC:HGNC:11089|Ensembl:ENSG00000170290|Vega:OTTHUMG00000166364 +6590 SLPI MIM:107285|HGNC:HGNC:11092|Ensembl:ENSG00000124107|Vega:OTTHUMG00000033075 +6591 SNAI2 MIM:602150|HGNC:HGNC:11094|Ensembl:ENSG00000019549|Vega:OTTHUMG00000149912 +6594 SMARCA1 MIM:300012|HGNC:HGNC:11097|Ensembl:ENSG00000102038|Vega:OTTHUMG00000022370 +6595 SMARCA2 MIM:600014|HGNC:HGNC:11098|Ensembl:ENSG00000080503|Vega:OTTHUMG00000019445 +6596 HLTF MIM:603257|HGNC:HGNC:11099|Ensembl:ENSG00000071794|Vega:OTTHUMG00000159534 +6597 SMARCA4 MIM:603254|HGNC:HGNC:11100|Ensembl:ENSG00000127616|Vega:OTTHUMG00000169272 +6598 SMARCB1 MIM:601607|HGNC:HGNC:11103|Ensembl:ENSG00000099956|Vega:OTTHUMG00000150737 +6599 SMARCC1 MIM:601732|HGNC:HGNC:11104|Ensembl:ENSG00000173473|Vega:OTTHUMG00000133519 +6601 SMARCC2 MIM:601734|HGNC:HGNC:11105|Ensembl:ENSG00000139613|Vega:OTTHUMG00000170288 +6602 SMARCD1 MIM:601735|HGNC:HGNC:11106|Ensembl:ENSG00000066117|Vega:OTTHUMG00000150194 +6603 SMARCD2 MIM:601736|HGNC:HGNC:11107|Ensembl:ENSG00000108604|Vega:OTTHUMG00000179045 +6604 SMARCD3 MIM:601737|HGNC:HGNC:11108|Ensembl:ENSG00000082014|Vega:OTTHUMG00000157431 +6605 SMARCE1 MIM:603111|HGNC:HGNC:11109|Ensembl:ENSG00000073584|Vega:OTTHUMG00000133367 +6606 SMN1 MIM:600354|HGNC:HGNC:11117|Ensembl:ENSG00000172062|Vega:OTTHUMG00000099361 +6607 SMN2 MIM:601627|HGNC:HGNC:11118|Ensembl:ENSG00000205571|Vega:OTTHUMG00000099389 +6608 SMO MIM:601500|HGNC:HGNC:11119|Ensembl:ENSG00000128602|Vega:OTTHUMG00000158421 +6609 SMPD1 MIM:607608|HGNC:HGNC:11120|Ensembl:ENSG00000166311|Vega:OTTHUMG00000165453 +6610 SMPD2 MIM:603498|HGNC:HGNC:11121|Ensembl:ENSG00000135587|Vega:OTTHUMG00000015348 +6611 SMS MIM:300105|HGNC:HGNC:11123|Ensembl:ENSG00000102172|Vega:OTTHUMG00000021239 +6612 SUMO3 MIM:602231|HGNC:HGNC:11124|Ensembl:ENSG00000184900|Vega:OTTHUMG00000090256 +6613 SUMO2 MIM:603042|HGNC:HGNC:11125|Ensembl:ENSG00000188612|Vega:OTTHUMG00000179481 +6614 SIGLEC1 MIM:600751|HGNC:HGNC:11127|Ensembl:ENSG00000088827|Vega:OTTHUMG00000031757 +6615 SNAI1 MIM:604238|HGNC:HGNC:11128|Ensembl:ENSG00000124216|Vega:OTTHUMG00000033048 +6616 SNAP25 MIM:600322|HGNC:HGNC:11132|Ensembl:ENSG00000132639|Vega:OTTHUMG00000031863 +6617 SNAPC1 MIM:600591|HGNC:HGNC:11134|Ensembl:ENSG00000023608|Vega:OTTHUMG00000140343 +6618 SNAPC2 MIM:605076|HGNC:HGNC:11135|Ensembl:ENSG00000104976|Vega:OTTHUMG00000182456 +6619 SNAPC3 MIM:602348|HGNC:HGNC:11136|Ensembl:ENSG00000164975|Vega:OTTHUMG00000019583 +6620 SNCB MIM:602569|HGNC:HGNC:11140|Ensembl:ENSG00000074317|Vega:OTTHUMG00000130661 +6621 SNAPC4 MIM:602777|HGNC:HGNC:11137|Ensembl:ENSG00000165684|Vega:OTTHUMG00000020929 +6622 SNCA MIM:163890|HGNC:HGNC:11138|Ensembl:ENSG00000145335|Vega:OTTHUMG00000130948 +6623 SNCG MIM:602998|HGNC:HGNC:11141|Ensembl:ENSG00000173267|Vega:OTTHUMG00000018656 +6624 FSCN1 MIM:602689|HGNC:HGNC:11148|Ensembl:ENSG00000075618|Vega:OTTHUMG00000090599 +6625 SNRNP70 MIM:180740|HGNC:HGNC:11150|Ensembl:ENSG00000104852|Vega:OTTHUMG00000183344 +6626 SNRPA MIM:182285|HGNC:HGNC:11151|Ensembl:ENSG00000077312|Vega:OTTHUMG00000182689 +6627 SNRPA1 MIM:603521|HGNC:HGNC:11152|Ensembl:ENSG00000131876|Vega:OTTHUMG00000149871 +6628 SNRPB MIM:182282|HGNC:HGNC:11153|Ensembl:ENSG00000125835|Vega:OTTHUMG00000031694 +6629 SNRPB2 MIM:603520|HGNC:HGNC:11155|Ensembl:ENSG00000125870|Vega:OTTHUMG00000031933 +6631 SNRPC MIM:603522|HGNC:HGNC:11157|Ensembl:ENSG00000124562|Vega:OTTHUMG00000014555 +6632 SNRPD1 MIM:601063|HGNC:HGNC:11158|Ensembl:ENSG00000167088|Vega:OTTHUMG00000178934 +6633 SNRPD2 MIM:601061|HGNC:HGNC:11159|Ensembl:ENSG00000125743|Vega:OTTHUMG00000182130 +6634 SNRPD3 MIM:601062|HGNC:HGNC:11160|Ensembl:ENSG00000100028|Vega:OTTHUMG00000150727 +6635 SNRPE MIM:128260|HGNC:HGNC:11161|Ensembl:ENSG00000182004|Vega:OTTHUMG00000035985 +6636 SNRPF MIM:603541|HGNC:HGNC:11162|Ensembl:ENSG00000139343|Vega:OTTHUMG00000170351 +6637 SNRPG MIM:603542|HGNC:HGNC:11163|Ensembl:ENSG00000143977|Vega:OTTHUMG00000129670 +6638 SNRPN MIM:182279|HGNC:HGNC:11164|Ensembl:ENSG00000128739|Vega:OTTHUMG00000129180 +6640 SNTA1 MIM:601017|HGNC:HGNC:11167|Ensembl:ENSG00000101400|Vega:OTTHUMG00000032259 +6641 SNTB1 MIM:600026|HGNC:HGNC:11168|Ensembl:ENSG00000172164|Vega:OTTHUMG00000165041 +6642 SNX1 MIM:601272|HGNC:HGNC:11172|Ensembl:ENSG00000028528|Vega:OTTHUMG00000172436 +6643 SNX2 MIM:605929|HGNC:HGNC:11173|Ensembl:ENSG00000205302|Vega:OTTHUMG00000163020 +6644 SRIP1 HGNC:HGNC:11293 +6645 SNTB2 MIM:600027|HGNC:HGNC:11169|Ensembl:ENSG00000168807|Vega:OTTHUMG00000137567 +6646 SOAT1 MIM:102642|HGNC:HGNC:11177|Ensembl:ENSG00000057252|Vega:OTTHUMG00000035253 +6647 SOD1 MIM:147450|HGNC:HGNC:11179|Ensembl:ENSG00000142168|Vega:OTTHUMG00000084878 +6648 SOD2 MIM:147460|HGNC:HGNC:11180|Ensembl:ENSG00000112096|Vega:OTTHUMG00000015940 +6649 SOD3 MIM:185490|HGNC:HGNC:11181|Ensembl:ENSG00000109610|Vega:OTTHUMG00000128565 +6650 CAPN15 MIM:603267|HGNC:HGNC:11182|Ensembl:ENSG00000103326|Vega:OTTHUMG00000119059 +6651 SON MIM:182465|HGNC:HGNC:11183|Ensembl:ENSG00000159140|Vega:OTTHUMG00000065806 +6652 SORD MIM:182500|HGNC:HGNC:11184|Ensembl:ENSG00000140263|Vega:OTTHUMG00000131265 +6653 SORL1 MIM:602005|HGNC:HGNC:11185|Ensembl:ENSG00000137642|Vega:OTTHUMG00000166057 +6654 SOS1 MIM:182530|HGNC:HGNC:11187|Ensembl:ENSG00000115904|Vega:OTTHUMG00000102109 +6655 SOS2 MIM:601247|HGNC:HGNC:11188|Ensembl:ENSG00000100485|Vega:OTTHUMG00000140292 +6656 SOX1 MIM:602148|HGNC:HGNC:11189|Ensembl:ENSG00000182968|Vega:OTTHUMG00000017362 +6657 SOX2 MIM:184429|HGNC:HGNC:11195|Ensembl:ENSG00000181449|Vega:OTTHUMG00000158222 +6658 SOX3 MIM:313430|HGNC:HGNC:11199|Ensembl:ENSG00000134595|Vega:OTTHUMG00000022544 +6659 SOX4 MIM:184430|HGNC:HGNC:11200|Ensembl:ENSG00000124766|Vega:OTTHUMG00000016101 +6660 SOX5 MIM:604975|HGNC:HGNC:11201|Ensembl:ENSG00000134532|Vega:OTTHUMG00000169026 +6661 SOX5P1 HGNC:HGNC:11202 +6662 SOX9 MIM:608160|HGNC:HGNC:11204|Ensembl:ENSG00000125398|Vega:OTTHUMG00000166300 +6663 SOX10 MIM:602229|HGNC:HGNC:11190|Ensembl:ENSG00000100146|Vega:OTTHUMG00000149913 +6664 SOX11 MIM:600898|HGNC:HGNC:11191|Ensembl:ENSG00000176887|Vega:OTTHUMG00000090333 +6665 SOX15 MIM:601297|HGNC:HGNC:11196|Ensembl:ENSG00000129194|Vega:OTTHUMG00000178146 +6666 SOX12 MIM:601947|HGNC:HGNC:11198|Ensembl:ENSG00000177732|Vega:OTTHUMG00000031623 +6667 SP1 MIM:189906|HGNC:HGNC:11205|Ensembl:ENSG00000185591|Vega:OTTHUMG00000170047 +6668 SP2 MIM:601801|HGNC:HGNC:11207|Ensembl:ENSG00000167182|Vega:OTTHUMG00000150196 +6670 SP3 MIM:601804|HGNC:HGNC:11208|Ensembl:ENSG00000172845|Vega:OTTHUMG00000132333 +6671 SP4 MIM:600540|HGNC:HGNC:11209|Ensembl:ENSG00000105866|Vega:OTTHUMG00000094801 +6672 SP100 MIM:604585|HGNC:HGNC:11206|Ensembl:ENSG00000067066|Vega:OTTHUMG00000133203 +6674 SPAG1 MIM:603395|HGNC:HGNC:11212|Ensembl:ENSG00000104450|Vega:OTTHUMG00000164706 +6675 UAP1 MIM:602862|HGNC:HGNC:12457|Ensembl:ENSG00000117143|Vega:OTTHUMG00000034419 +6676 SPAG4 MIM:603038|HGNC:HGNC:11214|Ensembl:ENSG00000061656|Vega:OTTHUMG00000032352 +6677 SPAM1 MIM:600930|HGNC:HGNC:11217|Ensembl:ENSG00000106304|Vega:OTTHUMG00000157284 +6678 SPARC MIM:182120|HGNC:HGNC:11219|Ensembl:ENSG00000113140|Vega:OTTHUMG00000130122 +6682 SPG3B HGNC:HGNC:11232 +6683 SPAST MIM:604277|HGNC:HGNC:11233|Ensembl:ENSG00000021574|Vega:OTTHUMG00000128455 +6685 SPG5B MIM:600146|HGNC:HGNC:11235 +6687 SPG7 MIM:602783|HGNC:HGNC:11237|Ensembl:ENSG00000197912|Vega:OTTHUMG00000138046 +6688 SPI1 MIM:165170|HGNC:HGNC:11241|Ensembl:ENSG00000066336|Vega:OTTHUMG00000150150 +6689 SPIB MIM:606802|HGNC:HGNC:11242|Ensembl:ENSG00000269404|Vega:OTTHUMG00000183039 +6690 SPINK1 MIM:167790|HGNC:HGNC:11244|Ensembl:ENSG00000164266|Vega:OTTHUMG00000129730 +6691 SPINK2 MIM:605753|HGNC:HGNC:11245|Ensembl:ENSG00000128040|Vega:OTTHUMG00000128769 +6692 SPINT1 MIM:605123|HGNC:HGNC:11246|Ensembl:ENSG00000166145|Vega:OTTHUMG00000130068 +6693 SPN MIM:182160|HGNC:HGNC:11249|Ensembl:ENSG00000197471|Vega:OTTHUMG00000097765 +6694 SPP2 MIM:602637|HGNC:HGNC:11256|Ensembl:ENSG00000072080|Vega:OTTHUMG00000059208 +6695 SPOCK1 MIM:602264|HGNC:HGNC:11251|Ensembl:ENSG00000152377|Vega:OTTHUMG00000129157 +6696 SPP1 MIM:166490|HGNC:HGNC:11255|Ensembl:ENSG00000118785|Vega:OTTHUMG00000130599 +6697 SPR MIM:182125|HGNC:HGNC:11257|Ensembl:ENSG00000116096|Vega:OTTHUMG00000129777 +6698 SPRR1A MIM:182265|HGNC:HGNC:11259|Ensembl:ENSG00000169474|Vega:OTTHUMG00000014404 +6699 SPRR1B MIM:182266|HGNC:HGNC:11260|Ensembl:ENSG00000169469|Vega:OTTHUMG00000013869 +6700 SPRR2A MIM:182267|HGNC:HGNC:11261|Ensembl:ENSG00000241794|Vega:OTTHUMG00000014395 +6701 SPRR2B MIM:182268|HGNC:HGNC:11262|Ensembl:ENSG00000196805|Vega:OTTHUMG00000013863 +6702 SPRR2C MIM:182269|HGNC:HGNC:11263 +6703 SPRR2D HGNC:HGNC:11264|Ensembl:ENSG00000163216|Vega:OTTHUMG00000014396 +6704 SPRR2E HGNC:HGNC:11265|Ensembl:ENSG00000203785|Vega:OTTHUMG00000014397 +6705 SPRR2F HGNC:HGNC:11266|Ensembl:ENSG00000244094|Vega:OTTHUMG00000014398 +6706 SPRR2G HGNC:HGNC:11267|Ensembl:ENSG00000159516|Vega:OTTHUMG00000014399 +6707 SPRR3 MIM:182271|HGNC:HGNC:11268|Ensembl:ENSG00000163209|Vega:OTTHUMG00000013872 +6708 SPTA1 MIM:182860|HGNC:HGNC:11272|Ensembl:ENSG00000163554|Vega:OTTHUMG00000019636 +6709 SPTAN1 MIM:182810|HGNC:HGNC:11273|Ensembl:ENSG00000197694|Vega:OTTHUMG00000020754 +6710 SPTB MIM:182870|HGNC:HGNC:11274|Ensembl:ENSG00000070182|Vega:OTTHUMG00000171550 +6711 SPTBN1 MIM:182790|HGNC:HGNC:11275|Ensembl:ENSG00000115306|Vega:OTTHUMG00000133746 +6712 SPTBN2 MIM:604985|HGNC:HGNC:11276|Ensembl:ENSG00000173898|Vega:OTTHUMG00000167262 +6713 SQLE MIM:602019|HGNC:HGNC:11279|Ensembl:ENSG00000104549|Vega:OTTHUMG00000164990 +6714 SRC MIM:190090|HGNC:HGNC:11283|Ensembl:ENSG00000197122|Vega:OTTHUMG00000032417 +6715 SRD5A1 MIM:184753|HGNC:HGNC:11284|Ensembl:ENSG00000145545|Vega:OTTHUMG00000090456 +6716 SRD5A2 MIM:607306|HGNC:HGNC:11285|Ensembl:ENSG00000277893|Vega:OTTHUMG00000152057 +6717 SRI MIM:182520|HGNC:HGNC:11292|Ensembl:ENSG00000075142|Vega:OTTHUMG00000157267 +6718 AKR1D1 MIM:604741|HGNC:HGNC:388|Ensembl:ENSG00000122787|Vega:OTTHUMG00000155787 +6719 SRD5A1P1 HGNC:HGNC:11286 +6720 SREBF1 MIM:184756|HGNC:HGNC:11289|Ensembl:ENSG00000072310|Vega:OTTHUMG00000059313 +6721 SREBF2 MIM:600481|HGNC:HGNC:11290|Ensembl:ENSG00000198911|Vega:OTTHUMG00000151261 +6722 SRF MIM:600589|HGNC:HGNC:11291|Ensembl:ENSG00000112658|Vega:OTTHUMG00000014722 +6723 SRM MIM:182891|HGNC:HGNC:11296|Ensembl:ENSG00000116649|Vega:OTTHUMG00000002119 +6725 SRMS HGNC:HGNC:11298|Ensembl:ENSG00000125508|Vega:OTTHUMG00000032977 +6726 SRP9 MIM:600707|HGNC:HGNC:11304|Ensembl:ENSG00000143742|Vega:OTTHUMG00000037738 +6727 SRP14 MIM:600708|HGNC:HGNC:11299|Ensembl:ENSG00000140319|Vega:OTTHUMG00000172391 +6728 SRP19 MIM:182175|HGNC:HGNC:11300|Ensembl:ENSG00000153037|Vega:OTTHUMG00000186064 +6729 SRP54 MIM:604857|HGNC:HGNC:11301|Ensembl:ENSG00000100883|Vega:OTTHUMG00000140214 +6730 SRP68 MIM:604858|HGNC:HGNC:11302|Ensembl:ENSG00000167881|Vega:OTTHUMG00000180054 +6731 SRP72 MIM:602122|HGNC:HGNC:11303|Ensembl:ENSG00000174780|Vega:OTTHUMG00000128843 +6732 SRPK1 MIM:601939|HGNC:HGNC:11305|Ensembl:ENSG00000096063|Vega:OTTHUMG00000014583 +6733 SRPK2 MIM:602980|HGNC:HGNC:11306|Ensembl:ENSG00000135250|Vega:OTTHUMG00000157405 +6734 SRPRA MIM:182180|HGNC:HGNC:11307|Ensembl:ENSG00000182934|Vega:OTTHUMG00000165826 +6736 SRY MIM:480000|HGNC:HGNC:11311|Ensembl:ENSG00000184895|Vega:OTTHUMG00000036084 +6737 TRIM21 MIM:109092|HGNC:HGNC:11312|Ensembl:ENSG00000132109|Vega:OTTHUMG00000165701 +6738 TROVE2 MIM:600063|HGNC:HGNC:11313|Ensembl:ENSG00000116747|Vega:OTTHUMG00000035675 +6739 SSAV1 MIM:182090 +6741 SSB MIM:109090|HGNC:HGNC:11316|Ensembl:ENSG00000138385|Vega:OTTHUMG00000132212 +6742 SSBP1 MIM:600439|HGNC:HGNC:11317|Ensembl:ENSG00000106028|Vega:OTTHUMG00000157572 +6744 SSFA2 MIM:118990|HGNC:HGNC:11319|Ensembl:ENSG00000138434|Vega:OTTHUMG00000132584 +6745 SSR1 MIM:600868|HGNC:HGNC:11323|Ensembl:ENSG00000124783|Vega:OTTHUMG00000014202 +6746 SSR2 MIM:600867|HGNC:HGNC:11324|Ensembl:ENSG00000163479|Vega:OTTHUMG00000017456 +6747 SSR3 MIM:606213|HGNC:HGNC:11325|Ensembl:ENSG00000114850|Vega:OTTHUMG00000158632 +6748 SSR4 MIM:300090|HGNC:HGNC:11326|Ensembl:ENSG00000180879|Vega:OTTHUMG00000024212 +6749 SSRP1 MIM:604328|HGNC:HGNC:11327|Ensembl:ENSG00000149136|Vega:OTTHUMG00000167024 +6750 SST MIM:182450|HGNC:HGNC:11329|Ensembl:ENSG00000157005|Vega:OTTHUMG00000156462 +6751 SSTR1 MIM:182451|HGNC:HGNC:11330|Ensembl:ENSG00000139874|Vega:OTTHUMG00000140249 +6752 SSTR2 MIM:182452|HGNC:HGNC:11331|Ensembl:ENSG00000180616|Vega:OTTHUMG00000178343 +6753 SSTR3 MIM:182453|HGNC:HGNC:11332|Ensembl:ENSG00000278195|Vega:OTTHUMG00000150537 +6754 SSTR4 MIM:182454|HGNC:HGNC:11333|Ensembl:ENSG00000132671|Vega:OTTHUMG00000032054 +6755 SSTR5 MIM:182455|HGNC:HGNC:11334|Ensembl:ENSG00000162009|Vega:OTTHUMG00000047842 +6756 SSX1 MIM:312820|HGNC:HGNC:11335|Ensembl:ENSG00000126752|Vega:OTTHUMG00000021488 +6757 SSX2 MIM:300192|HGNC:HGNC:11336|Ensembl:ENSG00000241476|Vega:OTTHUMG00000022697 +6758 SSX5 MIM:300327|HGNC:HGNC:11339|Ensembl:ENSG00000165583|Vega:OTTHUMG00000021471 +6759 SSX4 MIM:300326|HGNC:HGNC:11338|Ensembl:ENSG00000268009|Vega:OTTHUMG00000022698 +6760 SS18 MIM:600192|HGNC:HGNC:11340|Ensembl:ENSG00000141380|Vega:OTTHUMG00000179425 +6761 ST2 MIM:185440|HGNC:HGNC:11347 +6762 ST3 MIM:191181|HGNC:HGNC:11348 +6764 ST5 MIM:140750|HGNC:HGNC:11350|Ensembl:ENSG00000166444|Vega:OTTHUMG00000165835 +6765 ST8 MIM:167000|HGNC:HGNC:11352 +6767 ST13 MIM:606796|HGNC:HGNC:11343|Ensembl:ENSG00000100380|Vega:OTTHUMG00000151201 +6768 ST14 MIM:606797|HGNC:HGNC:11344|Ensembl:ENSG00000149418|Vega:OTTHUMG00000165768 +6769 STAC MIM:602317|HGNC:HGNC:11353|Ensembl:ENSG00000144681|Vega:OTTHUMG00000130798 +6770 STAR MIM:600617|HGNC:HGNC:11359|Ensembl:ENSG00000147465|Vega:OTTHUMG00000164058 +6771 STARP1 HGNC:HGNC:11360 +6772 STAT1 MIM:600555|HGNC:HGNC:11362|Ensembl:ENSG00000115415|Vega:OTTHUMG00000132699 +6773 STAT2 MIM:600556|HGNC:HGNC:11363|Ensembl:ENSG00000170581|Vega:OTTHUMG00000170760 +6774 STAT3 MIM:102582|HGNC:HGNC:11364|Ensembl:ENSG00000168610|Vega:OTTHUMG00000150645 +6775 STAT4 MIM:600558|HGNC:HGNC:11365|Ensembl:ENSG00000138378|Vega:OTTHUMG00000132700 +6776 STAT5A MIM:601511|HGNC:HGNC:11366|Ensembl:ENSG00000126561|Vega:OTTHUMG00000150725 +6777 STAT5B MIM:604260|HGNC:HGNC:11367|Ensembl:ENSG00000173757|Vega:OTTHUMG00000150724 +6778 STAT6 MIM:601512|HGNC:HGNC:11368|Ensembl:ENSG00000166888|Vega:OTTHUMG00000171194 +6779 STATH MIM:184470|HGNC:HGNC:11369|Ensembl:ENSG00000126549|Vega:OTTHUMG00000129394 +6780 STAU1 MIM:601716|HGNC:HGNC:11370|Ensembl:ENSG00000124214|Vega:OTTHUMG00000032691 +6781 STC1 MIM:601185|HGNC:HGNC:11373|Ensembl:ENSG00000159167|Vega:OTTHUMG00000097853 +6782 HSPA13 MIM:601100|HGNC:HGNC:11375|Ensembl:ENSG00000155304|Vega:OTTHUMG00000074261 +6783 SULT1E1 MIM:600043|HGNC:HGNC:11377|Ensembl:ENSG00000109193|Vega:OTTHUMG00000129403 +6785 ELOVL4 MIM:605512|HGNC:HGNC:14415|Ensembl:ENSG00000118402|Vega:OTTHUMG00000015087 +6786 STIM1 MIM:605921|HGNC:HGNC:11386|Ensembl:ENSG00000167323|Vega:OTTHUMG00000133360 +6787 NEK4 MIM:601959|HGNC:HGNC:11399|Ensembl:ENSG00000114904|Vega:OTTHUMG00000158836 +6788 STK3 MIM:605030|HGNC:HGNC:11406|Ensembl:ENSG00000104375|Vega:OTTHUMG00000164651 +6789 STK4 MIM:604965|HGNC:HGNC:11408|Ensembl:ENSG00000101109|Vega:OTTHUMG00000033059 +6790 AURKA MIM:603072|HGNC:HGNC:11393|Ensembl:ENSG00000087586|Vega:OTTHUMG00000032796 +6791 AURKAPS1 HGNC:HGNC:18611 +6792 CDKL5 MIM:300203|HGNC:HGNC:11411|Ensembl:ENSG00000008086|Vega:OTTHUMG00000021214 +6793 STK10 MIM:603919|HGNC:HGNC:11388|Ensembl:ENSG00000072786|Vega:OTTHUMG00000163265 +6794 STK11 MIM:602216|HGNC:HGNC:11389|Ensembl:ENSG00000118046|Vega:OTTHUMG00000180118 +6795 AURKC MIM:603495|HGNC:HGNC:11391|Ensembl:ENSG00000105146|Vega:OTTHUMG00000183106 +6799 SULT1A2 MIM:601292|HGNC:HGNC:11454|Ensembl:ENSG00000197165|Vega:OTTHUMG00000048082 +6801 STRN MIM:614765|HGNC:HGNC:11424|Ensembl:ENSG00000115808|Vega:OTTHUMG00000100959 +6803 STSP1 HGNC:HGNC:11426 +6804 STX1A MIM:186590|HGNC:HGNC:11433|Ensembl:ENSG00000106089|Vega:OTTHUMG00000137422 +6809 STX3 MIM:600876|HGNC:HGNC:11438|Ensembl:ENSG00000166900|Vega:OTTHUMG00000167353 +6810 STX4 MIM:186591|HGNC:HGNC:11439|Ensembl:ENSG00000103496|Vega:OTTHUMG00000132404 +6811 STX5 MIM:603189|HGNC:HGNC:11440|Ensembl:ENSG00000162236|Vega:OTTHUMG00000143864 +6812 STXBP1 MIM:602926|HGNC:HGNC:11444|Ensembl:ENSG00000136854|Vega:OTTHUMG00000020713 +6813 STXBP2 MIM:601717|HGNC:HGNC:11445|Ensembl:ENSG00000076944|Vega:OTTHUMG00000182396 +6814 STXBP3 MIM:608339|HGNC:HGNC:11446|Ensembl:ENSG00000116266|Vega:OTTHUMG00000011122 +6815 STYX MIM:615814|HGNC:HGNC:11447|Ensembl:ENSG00000198252|Vega:OTTHUMG00000140306 +6817 SULT1A1 MIM:171150|HGNC:HGNC:11453|Ensembl:ENSG00000196502|Vega:OTTHUMG00000131765 +6818 SULT1A3 MIM:600641|HGNC:HGNC:11455|Ensembl:ENSG00000261052|Vega:OTTHUMG00000048083 +6819 SULT1C2 MIM:602385|HGNC:HGNC:11456|Ensembl:ENSG00000198203|Vega:OTTHUMG00000153215 +6820 SULT2B1 MIM:604125|HGNC:HGNC:11459|Ensembl:ENSG00000088002|Vega:OTTHUMG00000183314 +6821 SUOX MIM:606887|HGNC:HGNC:11460|Ensembl:ENSG00000139531|Vega:OTTHUMG00000128503 +6822 SULT2A1 MIM:125263|HGNC:HGNC:11458|Ensembl:ENSG00000105398|Vega:OTTHUMG00000162469 +6824 ETF1P1 HGNC:HGNC:3478 +6825 ETF1P2 HGNC:HGNC:3479 +6827 SUPT4H1 MIM:603555|HGNC:HGNC:11467|Ensembl:ENSG00000213246|Vega:OTTHUMG00000178926 +6829 SUPT5H MIM:602102|HGNC:HGNC:11469|Ensembl:ENSG00000196235|Vega:OTTHUMG00000182973 +6830 SUPT6H MIM:601333|HGNC:HGNC:11470|Ensembl:ENSG00000109111|Vega:OTTHUMG00000179449 +6832 SUPV3L1 MIM:605122|HGNC:HGNC:11471|Ensembl:ENSG00000156502|Vega:OTTHUMG00000018375 +6833 ABCC8 MIM:600509|HGNC:HGNC:59|Ensembl:ENSG00000006071|Vega:OTTHUMG00000166316 +6834 SURF1 MIM:185620|HGNC:HGNC:11474|Ensembl:ENSG00000148290|Vega:OTTHUMG00000020866 +6835 SURF2 MIM:185630|HGNC:HGNC:11475|Ensembl:ENSG00000148291|Vega:OTTHUMG00000020867 +6836 SURF4 MIM:185660|HGNC:HGNC:11476|Ensembl:ENSG00000148248|Vega:OTTHUMG00000020868 +6837 MED22 MIM:185641|HGNC:HGNC:11477|Ensembl:ENSG00000148297|Vega:OTTHUMG00000020869 +6838 SURF6 MIM:185642|HGNC:HGNC:11478|Ensembl:ENSG00000148296|Vega:OTTHUMG00000020871 +6839 SUV39H1 MIM:300254|HGNC:HGNC:11479|Ensembl:ENSG00000101945|Vega:OTTHUMG00000022701 +6840 SVIL MIM:604126|HGNC:HGNC:11480|Ensembl:ENSG00000197321|Vega:OTTHUMG00000017882 +6843 VAMP1 MIM:185880|HGNC:HGNC:12642|Ensembl:ENSG00000139190|Vega:OTTHUMG00000168269 +6844 VAMP2 MIM:185881|HGNC:HGNC:12643|Ensembl:ENSG00000220205|Ensembl:ENSG00000263620|Vega:OTTHUMG00000150254|Vega:OTTHUMG00000178326 +6845 VAMP7 MIM:300053|HGNC:HGNC:11486|Ensembl:ENSG00000124333|Vega:OTTHUMG00000022679 +6846 XCL2 MIM:604828|HGNC:HGNC:10646|Ensembl:ENSG00000143185|Vega:OTTHUMG00000034549 +6847 SYCP1 MIM:602162|HGNC:HGNC:11487|Ensembl:ENSG00000198765|Vega:OTTHUMG00000012057 +6850 SYK MIM:600085|HGNC:HGNC:11491|Ensembl:ENSG00000165025|Vega:OTTHUMG00000020200 +6852 SYM2 HGNC:HGNC:11493 +6853 SYN1 MIM:313440|HGNC:HGNC:11494|Ensembl:ENSG00000008056|Vega:OTTHUMG00000021454 +6854 SYN2 MIM:600755|HGNC:HGNC:11495|Ensembl:ENSG00000157152|Vega:OTTHUMG00000155335 +6855 SYP MIM:313475|HGNC:HGNC:11506|Ensembl:ENSG00000102003|Vega:OTTHUMG00000034557 +6856 SYPL1 MIM:616665|HGNC:HGNC:11507|Ensembl:ENSG00000008282|Vega:OTTHUMG00000157587 +6857 SYT1 MIM:185605|HGNC:HGNC:11509|Ensembl:ENSG00000067715|Vega:OTTHUMG00000134326 +6860 SYT4 MIM:600103|HGNC:HGNC:11512|Ensembl:ENSG00000132872|Vega:OTTHUMG00000132610 +6861 SYT5 MIM:600782|HGNC:HGNC:11513|Ensembl:ENSG00000129990|Vega:OTTHUMG00000180669 +6862 T MIM:601397|HGNC:HGNC:11515|Ensembl:ENSG00000164458|Vega:OTTHUMG00000015991 +6863 TAC1 MIM:162320|HGNC:HGNC:11517|Ensembl:ENSG00000006128|Vega:OTTHUMG00000154069 +6865 TACR2 MIM:162321|HGNC:HGNC:11527|Ensembl:ENSG00000075073|Vega:OTTHUMG00000018377 +6866 TAC3 MIM:162330|HGNC:HGNC:11521|Ensembl:ENSG00000166863|Vega:OTTHUMG00000156958 +6867 TACC1 MIM:605301|HGNC:HGNC:11522|Ensembl:ENSG00000147526|Vega:OTTHUMG00000164018 +6868 ADAM17 MIM:603639|HGNC:HGNC:195|Ensembl:ENSG00000151694|Vega:OTTHUMG00000090425 +6869 TACR1 MIM:162323|HGNC:HGNC:11526|Ensembl:ENSG00000115353|Vega:OTTHUMG00000129973 +6870 TACR3 MIM:162332|HGNC:HGNC:11528|Ensembl:ENSG00000169836|Vega:OTTHUMG00000131124 +6871 TADA2A MIM:602276|HGNC:HGNC:11531|Ensembl:ENSG00000276234|Vega:OTTHUMG00000188469 +6872 TAF1 MIM:313650|HGNC:HGNC:11535|Ensembl:ENSG00000147133|Vega:OTTHUMG00000022723 +6873 TAF2 MIM:604912|HGNC:HGNC:11536|Ensembl:ENSG00000064313|Vega:OTTHUMG00000165009 +6874 TAF4 MIM:601796|HGNC:HGNC:11537|Ensembl:ENSG00000130699|Vega:OTTHUMG00000032893 +6875 TAF4B MIM:601689|HGNC:HGNC:11538|Ensembl:ENSG00000141384|Vega:OTTHUMG00000179429 +6876 TAGLN MIM:600818|HGNC:HGNC:11553|Ensembl:ENSG00000149591|Vega:OTTHUMG00000167067 +6877 TAF5 MIM:601787|HGNC:HGNC:11539|Ensembl:ENSG00000148835|Vega:OTTHUMG00000018985 +6878 TAF6 MIM:602955|HGNC:HGNC:11540|Ensembl:ENSG00000106290|Vega:OTTHUMG00000154771 +6879 TAF7 MIM:600573|HGNC:HGNC:11541|Ensembl:ENSG00000178913|Vega:OTTHUMG00000129628 +6880 TAF9 MIM:600822|HGNC:HGNC:11542|Ensembl:ENSG00000273841|Vega:OTTHUMG00000099359 +6881 TAF10 MIM:600475|HGNC:HGNC:11543|Ensembl:ENSG00000166337|Vega:OTTHUMG00000133402 +6882 TAF11 MIM:600772|HGNC:HGNC:11544|Ensembl:ENSG00000064995|Vega:OTTHUMG00000014556 +6883 TAF12 MIM:600773|HGNC:HGNC:11545|Ensembl:ENSG00000120656|Vega:OTTHUMG00000003655 +6884 TAF13 MIM:600774|HGNC:HGNC:11546|Ensembl:ENSG00000197780|Vega:OTTHUMG00000042363 +6885 MAP3K7 MIM:602614|HGNC:HGNC:6859|Ensembl:ENSG00000135341|Vega:OTTHUMG00000015217 +6886 TAL1 MIM:187040|HGNC:HGNC:11556|Ensembl:ENSG00000162367|Vega:OTTHUMG00000007847 +6887 TAL2 MIM:186855|HGNC:HGNC:11557|Ensembl:ENSG00000186051|Vega:OTTHUMG00000020424 +6888 TALDO1 MIM:602063|HGNC:HGNC:11559|Ensembl:ENSG00000177156|Vega:OTTHUMG00000133318 +6889 TALDO1P1 HGNC:HGNC:11560 +6890 TAP1 MIM:170260|HGNC:HGNC:43|Ensembl:ENSG00000168394|Vega:OTTHUMG00000031067 +6891 TAP2 MIM:170261|HGNC:HGNC:44|Ensembl:ENSG00000204267|Vega:OTTHUMG00000031068 +6892 TAPBP MIM:601962|HGNC:HGNC:11566|Ensembl:ENSG00000231925|Vega:OTTHUMG00000031090 +6893 TAPVR1 MIM:106700|HGNC:HGNC:11567 +6894 TARBP1 MIM:605052|HGNC:HGNC:11568|Ensembl:ENSG00000059588|Vega:OTTHUMG00000037947 +6895 TARBP2 MIM:605053|HGNC:HGNC:11569|Ensembl:ENSG00000139546|Vega:OTTHUMG00000169855 +6896 TARBP2P1 HGNC:HGNC:11570 +6897 TARS MIM:187790|HGNC:HGNC:11572|Ensembl:ENSG00000113407|Vega:OTTHUMG00000090683 +6898 TAT MIM:613018|HGNC:HGNC:11573|Ensembl:ENSG00000198650|Vega:OTTHUMG00000137590 +6899 TBX1 MIM:602054|HGNC:HGNC:11592|Ensembl:ENSG00000184058|Vega:OTTHUMG00000150421 +6900 CNTN2 MIM:190197|HGNC:HGNC:2172|Ensembl:ENSG00000184144|Vega:OTTHUMG00000037105 +6901 TAZ MIM:300394|HGNC:HGNC:11577|Ensembl:ENSG00000102125|Vega:OTTHUMG00000033190 +6902 TBCA MIM:610058|HGNC:HGNC:11579|Ensembl:ENSG00000171530|Vega:OTTHUMG00000102173 +6903 TBCC MIM:602971|HGNC:HGNC:11580|Ensembl:ENSG00000124659|Vega:OTTHUMG00000014704 +6904 TBCD MIM:604649|HGNC:HGNC:11581|Ensembl:ENSG00000141556|Vega:OTTHUMG00000177878 +6905 TBCE MIM:604934|HGNC:HGNC:11582|Ensembl:ENSG00000116957|Vega:OTTHUMG00000039987 +6906 SERPINA7 MIM:314200|HGNC:HGNC:11583|Ensembl:ENSG00000123561|Vega:OTTHUMG00000022144 +6907 TBL1X MIM:300196|HGNC:HGNC:11585|Ensembl:ENSG00000101849|Vega:OTTHUMG00000021117 +6908 TBP MIM:600075|HGNC:HGNC:11588|Ensembl:ENSG00000112592|Vega:OTTHUMG00000016084 +6909 TBX2 MIM:600747|HGNC:HGNC:11597|Ensembl:ENSG00000121068|Vega:OTTHUMG00000156986 +6910 TBX5 MIM:601620|HGNC:HGNC:11604|Ensembl:ENSG00000089225|Vega:OTTHUMG00000166191 +6911 TBX6 MIM:602427|HGNC:HGNC:11605|Ensembl:ENSG00000149922|Vega:OTTHUMG00000132115 +6913 TBX15 MIM:604127|HGNC:HGNC:11594|Ensembl:ENSG00000092607|Vega:OTTHUMG00000012263 +6914 TBXA1R HGNC:HGNC:11607 +6915 TBXA2R MIM:188070|HGNC:HGNC:11608|Ensembl:ENSG00000006638|Vega:OTTHUMG00000180806 +6916 TBXAS1 MIM:274180|HGNC:HGNC:11609|Ensembl:ENSG00000059377|Vega:OTTHUMG00000157302 +6917 TCEA1 MIM:601425|HGNC:HGNC:11612|Ensembl:ENSG00000187735|Vega:OTTHUMG00000164262 +6918 TCEA1P1 HGNC:HGNC:11613 +6919 TCEA2 MIM:604784|HGNC:HGNC:11614|Ensembl:ENSG00000171703|Vega:OTTHUMG00000033026 +6920 TCEA3 MIM:604128|HGNC:HGNC:11615|Ensembl:ENSG00000204219|Vega:OTTHUMG00000003233 +6921 ELOC MIM:600788|HGNC:HGNC:11617|Ensembl:ENSG00000154582|Vega:OTTHUMG00000164501 +6922 SKP1P1 HGNC:HGNC:33696 +6923 ELOB MIM:600787|HGNC:HGNC:11619|Ensembl:ENSG00000103363|Vega:OTTHUMG00000154125 +6924 ELOA MIM:600786|HGNC:HGNC:11620|Ensembl:ENSG00000011007|Vega:OTTHUMG00000002957 +6925 TCF4 MIM:602272|HGNC:HGNC:11634|Ensembl:ENSG00000196628|Vega:OTTHUMG00000132713 +6926 TBX3 MIM:601621|HGNC:HGNC:11602|Ensembl:ENSG00000135111|Vega:OTTHUMG00000169586 +6927 HNF1A MIM:142410|HGNC:HGNC:11621|Ensembl:ENSG00000135100|Vega:OTTHUMG00000151015 +6928 HNF1B MIM:189907|HGNC:HGNC:11630|Ensembl:ENSG00000275410|Vega:OTTHUMG00000188478 +6929 TCF3 MIM:147141|HGNC:HGNC:11633|Ensembl:ENSG00000071564|Vega:OTTHUMG00000180031 +6932 TCF7 MIM:189908|HGNC:HGNC:11639|Ensembl:ENSG00000081059|Vega:OTTHUMG00000129124 +6934 TCF7L2 MIM:602228|HGNC:HGNC:11641|Ensembl:ENSG00000148737|Vega:OTTHUMG00000019070 +6935 ZEB1 MIM:189909|HGNC:HGNC:11642|Ensembl:ENSG00000148516|Vega:OTTHUMG00000017907 +6936 GCFC2 MIM:189901|HGNC:HGNC:1317|Ensembl:ENSG00000005436|Vega:OTTHUMG00000129989 +6938 TCF12 MIM:600480|HGNC:HGNC:11623|Ensembl:ENSG00000140262|Vega:OTTHUMG00000132047 +6939 TCF15 MIM:601010|HGNC:HGNC:11627|Ensembl:ENSG00000125878|Vega:OTTHUMG00000031640 +6940 ZNF354A MIM:602444|HGNC:HGNC:11628|Ensembl:ENSG00000169131|Vega:OTTHUMG00000130895 +6941 TCF19 MIM:600912|HGNC:HGNC:11629|Ensembl:ENSG00000137310|Vega:OTTHUMG00000031274 +6942 TCF20 MIM:603107|HGNC:HGNC:11631|Ensembl:ENSG00000100207|Vega:OTTHUMG00000150920 +6943 TCF21 MIM:603306|HGNC:HGNC:11632|Ensembl:ENSG00000118526|Vega:OTTHUMG00000015608 +6944 VPS72 MIM:600607|HGNC:HGNC:11644|Ensembl:ENSG00000163159|Vega:OTTHUMG00000012345 +6945 MLX MIM:602976|HGNC:HGNC:11645|Ensembl:ENSG00000108788|Vega:OTTHUMG00000180246 +6946 TCL4 MIM:186860|HGNC:HGNC:11650 +6947 TCN1 MIM:189905|HGNC:HGNC:11652|Ensembl:ENSG00000134827|Vega:OTTHUMG00000167400 +6948 TCN2 MIM:613441|HGNC:HGNC:11653|Ensembl:ENSG00000185339|Vega:OTTHUMG00000151095 +6949 TCOF1 MIM:606847|HGNC:HGNC:11654|Ensembl:ENSG00000070814|Vega:OTTHUMG00000130081 +6950 TCP1 MIM:186980|HGNC:HGNC:11655|Ensembl:ENSG00000120438|Vega:OTTHUMG00000015937 +6952 TCP1P2 HGNC:HGNC:11660 +6953 TCP10 MIM:187020|HGNC:HGNC:11656|Ensembl:ENSG00000203690|Vega:OTTHUMG00000016026 +6954 TCP11 MIM:186982|HGNC:HGNC:11658|Ensembl:ENSG00000124678|Vega:OTTHUMG00000014560 +6955 TRA HGNC:HGNC:12027 +6956 TRAV6 HGNC:HGNC:12144|IMGT/GENE-DB:TRAV6 +6957 TRB HGNC:HGNC:12155 +6958 TRBV29OR9-2 HGNC:HGNC:12211|IMGT/GENE-DB:TRBV29/OR9-2 +6959 TRBV21OR9-2 HGNC:HGNC:12199|IMGT/GENE-DB:TRBV21/OR9-2 +6960 TRBV25OR9-2 HGNC:HGNC:12206|IMGT/GENE-DB:TRBV25/OR9-2 +6961 TRBV24OR9-2 HGNC:HGNC:12204|IMGT/GENE-DB:TRBV24/OR9-2 +6962 TRBV20OR9-2 HGNC:HGNC:12197|IMGT/GENE-DB:TRBV20/OR9-2 +6964 TRD HGNC:HGNC:12252 +6965 TRG HGNC:HGNC:12271 +6966 TRGC1 MIM:186970|HGNC:HGNC:12275|IMGT/GENE-DB:TRGC1 +6967 TRGC2 MIM:615450|HGNC:HGNC:12276|IMGT/GENE-DB:TRGC2 +6968 TRGJ1 HGNC:HGNC:12277|IMGT/GENE-DB:TRGJ1 +6969 TRGJ2 HGNC:HGNC:12278|IMGT/GENE-DB:TRGJ2 +6970 TRGJP HGNC:HGNC:12279|IMGT/GENE-DB:TRGJP +6971 TRGJP1 HGNC:HGNC:12280|IMGT/GENE-DB:TRGJP1 +6972 TRGJP2 HGNC:HGNC:12281|IMGT/GENE-DB:TRGJP2 +6973 TRGV1 HGNC:HGNC:12284|IMGT/GENE-DB:TRGV1 +6974 TRGV2 HGNC:HGNC:12287|IMGT/GENE-DB:TRGV2 +6975 TECTB MIM:602653|HGNC:HGNC:11721|Ensembl:ENSG00000119913|Vega:OTTHUMG00000019056 +6976 TRGV3 HGNC:HGNC:12288|IMGT/GENE-DB:TRGV3 +6977 TRGV4 HGNC:HGNC:12289|IMGT/GENE-DB:TRGV4 +6978 TRGV5 HGNC:HGNC:12290|IMGT/GENE-DB:TRGV5 +6979 TRGV5P HGNC:HGNC:12291|IMGT/GENE-DB:TRGV5P +6980 TRGV6 HGNC:HGNC:12292|IMGT/GENE-DB:TRGV6 +6981 TRGV7 HGNC:HGNC:12293|IMGT/GENE-DB:TRGV7 +6982 TRGV8 HGNC:HGNC:12294|IMGT/GENE-DB:TRGV8 +6983 TRGV9 HGNC:HGNC:12295|IMGT/GENE-DB:TRGV9 +6984 TRGV10 HGNC:HGNC:12285|IMGT/GENE-DB:TRGV10 +6985 TRGV11 HGNC:HGNC:12286|IMGT/GENE-DB:TRGV11 +6986 TRGVA HGNC:HGNC:12296|IMGT/GENE-DB:TRGVA +6987 TRGVB HGNC:HGNC:12297|IMGT/GENE-DB:TRGVB +6988 TCTA MIM:600690|HGNC:HGNC:11692|Ensembl:ENSG00000145022|Vega:OTTHUMG00000156846 +6990 DYNLT3 MIM:300302|HGNC:HGNC:11694|Ensembl:ENSG00000165169|Vega:OTTHUMG00000033172 +6991 TCTE3 MIM:186977|HGNC:HGNC:11695|Ensembl:ENSG00000184786|Vega:OTTHUMG00000016068 +6992 PPP1R11 MIM:606670|HGNC:HGNC:9285|Ensembl:ENSG00000204619|Vega:OTTHUMG00000031260 +6993 DYNLT1 MIM:601554|HGNC:HGNC:11697|Ensembl:ENSG00000146425|Vega:OTTHUMG00000015918 +6996 TDG MIM:601423|HGNC:HGNC:11700|Ensembl:ENSG00000139372|Vega:OTTHUMG00000168418 +6997 TDGF1 MIM:187395|HGNC:HGNC:11701|Ensembl:ENSG00000241186|Vega:OTTHUMG00000191661 +6998 TDGF1P3 HGNC:HGNC:11703|Ensembl:ENSG00000225366 +6999 TDO2 MIM:191070|HGNC:HGNC:11708|Ensembl:ENSG00000151790|Vega:OTTHUMG00000161838 +7001 PRDX2 MIM:600538|HGNC:HGNC:9353|Ensembl:ENSG00000167815|Vega:OTTHUMG00000134285 +7002 PRDX1P1 HGNC:HGNC:11711 +7003 TEAD1 MIM:189967|HGNC:HGNC:11714|Ensembl:ENSG00000187079|Vega:OTTHUMG00000165878 +7004 TEAD4 MIM:601714|HGNC:HGNC:11717|Ensembl:ENSG00000197905|Vega:OTTHUMG00000168153 +7005 TEAD3 MIM:603170|HGNC:HGNC:11716|Ensembl:ENSG00000007866|Vega:OTTHUMG00000014571 +7006 TEC MIM:600583|HGNC:HGNC:11719|Ensembl:ENSG00000135605|Vega:OTTHUMG00000128623 +7007 TECTA MIM:602574|HGNC:HGNC:11720|Ensembl:ENSG00000109927|Vega:OTTHUMG00000149908 +7008 TEF MIM:188595|HGNC:HGNC:11722|Ensembl:ENSG00000167074|Vega:OTTHUMG00000150968 +7009 TMBIM6 MIM:600748|HGNC:HGNC:11723|Ensembl:ENSG00000139644|Vega:OTTHUMG00000169652 +7010 TEK MIM:600221|HGNC:HGNC:11724|Ensembl:ENSG00000120156|Vega:OTTHUMG00000019712 +7011 TEP1 MIM:601686|HGNC:HGNC:11726|Ensembl:ENSG00000129566|Vega:OTTHUMG00000029515 +7012 TERC MIM:602322|HGNC:HGNC:11727|Ensembl:ENSG00000270141|Ensembl:ENSG00000277925 +7013 TERF1 MIM:600951|HGNC:HGNC:11728|Ensembl:ENSG00000147601|Vega:OTTHUMG00000164522 +7014 TERF2 MIM:602027|HGNC:HGNC:11729|Ensembl:ENSG00000132604|Vega:OTTHUMG00000137566 +7015 TERT MIM:187270|HGNC:HGNC:11730|Ensembl:ENSG00000164362|Vega:OTTHUMG00000090357 +7016 TESK1 MIM:601782|HGNC:HGNC:11731|Ensembl:ENSG00000107140|Vega:OTTHUMG00000019863 +7018 TF MIM:190000|HGNC:HGNC:11740|Ensembl:ENSG00000091513|Vega:OTTHUMG00000150356 +7019 TFAM MIM:600438|HGNC:HGNC:11741|Ensembl:ENSG00000108064|Vega:OTTHUMG00000018270 +7020 TFAP2A MIM:107580|HGNC:HGNC:11742|Ensembl:ENSG00000137203|Vega:OTTHUMG00000014235 +7021 TFAP2B MIM:601601|HGNC:HGNC:11743|Ensembl:ENSG00000008196|Vega:OTTHUMG00000014836 +7022 TFAP2C MIM:601602|HGNC:HGNC:11744|Ensembl:ENSG00000087510|Vega:OTTHUMG00000032805 +7023 TFAP4 MIM:600743|HGNC:HGNC:11745|Ensembl:ENSG00000090447|Vega:OTTHUMG00000129435 +7024 TFCP2 MIM:189889|HGNC:HGNC:11748|Ensembl:ENSG00000135457|Vega:OTTHUMG00000169621 +7025 NR2F1 MIM:132890|HGNC:HGNC:7975|Ensembl:ENSG00000175745|Vega:OTTHUMG00000119079 +7026 NR2F2 MIM:107773|HGNC:HGNC:7976|Ensembl:ENSG00000185551|Vega:OTTHUMG00000149848 +7027 TFDP1 MIM:189902|HGNC:HGNC:11749|Ensembl:ENSG00000198176|Vega:OTTHUMG00000017388 +7029 TFDP2 MIM:602160|HGNC:HGNC:11751|Ensembl:ENSG00000114126|Vega:OTTHUMG00000164975 +7030 TFE3 MIM:314310|HGNC:HGNC:11752|Ensembl:ENSG00000068323|Vega:OTTHUMG00000022690 +7031 TFF1 MIM:113710|HGNC:HGNC:11755|Ensembl:ENSG00000160182|Vega:OTTHUMG00000086799 +7032 TFF2 MIM:182590|HGNC:HGNC:11756|Ensembl:ENSG00000160181|Vega:OTTHUMG00000086797 +7033 TFF3 MIM:600633|HGNC:HGNC:11757|Ensembl:ENSG00000160180|Vega:OTTHUMG00000086798 +7035 TFPI MIM:152310|HGNC:HGNC:11760|Ensembl:ENSG00000003436|Vega:OTTHUMG00000132634 +7036 TFR2 MIM:604720|HGNC:HGNC:11762|Ensembl:ENSG00000106327|Vega:OTTHUMG00000159598 +7037 TFRC MIM:190010|HGNC:HGNC:11763|Ensembl:ENSG00000072274|Vega:OTTHUMG00000155714 +7038 TG MIM:188450|HGNC:HGNC:11764|Ensembl:ENSG00000042832|Vega:OTTHUMG00000164649 +7039 TGFA MIM:190170|HGNC:HGNC:11765|Ensembl:ENSG00000163235|Vega:OTTHUMG00000129669 +7040 TGFB1 MIM:190180|HGNC:HGNC:11766|Ensembl:ENSG00000105329|Vega:OTTHUMG00000182760 +7041 TGFB1I1 MIM:602353|HGNC:HGNC:11767|Ensembl:ENSG00000140682|Vega:OTTHUMG00000132467 +7042 TGFB2 MIM:190220|HGNC:HGNC:11768|Ensembl:ENSG00000092969|Vega:OTTHUMG00000039521 +7043 TGFB3 MIM:190230|HGNC:HGNC:11769|Ensembl:ENSG00000119699|Vega:OTTHUMG00000171489 +7044 LEFTY2 MIM:601877|HGNC:HGNC:3122|Ensembl:ENSG00000143768|Vega:OTTHUMG00000037441 +7045 TGFBI MIM:601692|HGNC:HGNC:11771|Ensembl:ENSG00000120708|Vega:OTTHUMG00000163213 +7046 TGFBR1 MIM:190181|HGNC:HGNC:11772|Ensembl:ENSG00000106799|Vega:OTTHUMG00000020353 +7047 TGM4 MIM:600585|HGNC:HGNC:11780|Ensembl:ENSG00000163810 +7048 TGFBR2 MIM:190182|HGNC:HGNC:11773|Ensembl:ENSG00000163513|Vega:OTTHUMG00000130569 +7049 TGFBR3 MIM:600742|HGNC:HGNC:11774|Ensembl:ENSG00000069702|Vega:OTTHUMG00000010097 +7050 TGIF1 MIM:602630|HGNC:HGNC:11776|Ensembl:ENSG00000177426|Vega:OTTHUMG00000131511 +7051 TGM1 MIM:190195|HGNC:HGNC:11777|Ensembl:ENSG00000092295|Vega:OTTHUMG00000029329 +7052 TGM2 MIM:190196|HGNC:HGNC:11778|Ensembl:ENSG00000198959|Vega:OTTHUMG00000032437 +7053 TGM3 MIM:600238|HGNC:HGNC:11779|Ensembl:ENSG00000125780|Vega:OTTHUMG00000031690 +7054 TH MIM:191290|HGNC:HGNC:11782|Ensembl:ENSG00000180176|Vega:OTTHUMG00000009559 +7055 THAS MIM:313850|HGNC:HGNC:11783 +7056 THBD MIM:188040|HGNC:HGNC:11784|Ensembl:ENSG00000178726|Vega:OTTHUMG00000032053 +7057 THBS1 MIM:188060|HGNC:HGNC:11785|Ensembl:ENSG00000137801|Vega:OTTHUMG00000133665 +7058 THBS2 MIM:188061|HGNC:HGNC:11786|Ensembl:ENSG00000186340|Vega:OTTHUMG00000045408 +7059 THBS3 MIM:188062|HGNC:HGNC:11787|Ensembl:ENSG00000169231|Vega:OTTHUMG00000035710 +7060 THBS4 MIM:600715|HGNC:HGNC:11788|Ensembl:ENSG00000113296|Vega:OTTHUMG00000108173 +7062 TCHH MIM:190370|HGNC:HGNC:11791|Ensembl:ENSG00000159450|Vega:OTTHUMG00000013066 +7063 THM MIM:274230|HGNC:HGNC:11792 +7064 THOP1 MIM:601117|HGNC:HGNC:11793|Ensembl:ENSG00000172009|Vega:OTTHUMG00000180492 +7066 THPO MIM:600044|HGNC:HGNC:11795|Ensembl:ENSG00000090534|Vega:OTTHUMG00000156745 +7067 THRA MIM:190120|HGNC:HGNC:11796|Ensembl:ENSG00000126351|Vega:OTTHUMG00000133332 +7068 THRB MIM:190160|HGNC:HGNC:11799|Ensembl:ENSG00000151090|Vega:OTTHUMG00000130478 +7069 THRSP MIM:601926|HGNC:HGNC:11800|Ensembl:ENSG00000151365|Vega:OTTHUMG00000166632 +7070 THY1 MIM:188230|HGNC:HGNC:11801|Ensembl:ENSG00000154096|Vega:OTTHUMG00000166202 +7071 KLF10 MIM:601878|HGNC:HGNC:11810|Ensembl:ENSG00000155090|Vega:OTTHUMG00000164735 +7072 TIA1 MIM:603518|HGNC:HGNC:11802|Ensembl:ENSG00000116001|Vega:OTTHUMG00000129644 +7073 TIAL1 MIM:603413|HGNC:HGNC:11804|Ensembl:ENSG00000151923|Vega:OTTHUMG00000019156 +7074 TIAM1 MIM:600687|HGNC:HGNC:11805|Ensembl:ENSG00000156299|Vega:OTTHUMG00000084869 +7075 TIE1 MIM:600222|HGNC:HGNC:11809|Ensembl:ENSG00000066056|Vega:OTTHUMG00000007282 +7076 TIMP1 MIM:305370|HGNC:HGNC:11820|Ensembl:ENSG00000102265|Vega:OTTHUMG00000021447 +7077 TIMP2 MIM:188825|HGNC:HGNC:11821|Ensembl:ENSG00000035862|Vega:OTTHUMG00000154517 +7078 TIMP3 MIM:188826|HGNC:HGNC:11822|Ensembl:ENSG00000100234|Vega:OTTHUMG00000030784 +7079 TIMP4 MIM:601915|HGNC:HGNC:11823|Ensembl:ENSG00000157150|Vega:OTTHUMG00000129763 +7080 NKX2-1 MIM:600635|HGNC:HGNC:11825|Ensembl:ENSG00000136352|Vega:OTTHUMG00000140225 +7082 TJP1 MIM:601009|HGNC:HGNC:11827|Ensembl:ENSG00000104067|Vega:OTTHUMG00000137397 +7083 TK1 MIM:188300|HGNC:HGNC:11830|Ensembl:ENSG00000167900|Vega:OTTHUMG00000150674 +7084 TK2 MIM:188250|HGNC:HGNC:11831|Ensembl:ENSG00000166548|Vega:OTTHUMG00000137499 +7085 TKCR MIM:314300|HGNC:HGNC:11833 +7086 TKT MIM:606781|HGNC:HGNC:11834|Ensembl:ENSG00000163931|Vega:OTTHUMG00000158192 +7087 ICAM5 MIM:601852|HGNC:HGNC:5348|Ensembl:ENSG00000105376|Vega:OTTHUMG00000180406 +7088 TLE1 MIM:600189|HGNC:HGNC:11837|Ensembl:ENSG00000196781|Vega:OTTHUMG00000021008 +7089 TLE2 MIM:601041|HGNC:HGNC:11838|Ensembl:ENSG00000065717|Vega:OTTHUMG00000180613 +7090 TLE3 MIM:600190|HGNC:HGNC:11839|Ensembl:ENSG00000140332|Vega:OTTHUMG00000172121 +7091 TLE4 MIM:605132|HGNC:HGNC:11840|Ensembl:ENSG00000106829|Vega:OTTHUMG00000020072 +7092 TLL1 MIM:606742|HGNC:HGNC:11843|Ensembl:ENSG00000038295|Vega:OTTHUMG00000161112 +7093 TLL2 MIM:606743|HGNC:HGNC:11844|Ensembl:ENSG00000095587|Vega:OTTHUMG00000018833 +7094 TLN1 MIM:186745|HGNC:HGNC:11845|Ensembl:ENSG00000137076|Vega:OTTHUMG00000019874 +7095 SEC62 MIM:602173|HGNC:HGNC:11846|Ensembl:ENSG00000008952|Vega:OTTHUMG00000158753 +7096 TLR1 MIM:601194|HGNC:HGNC:11847|Ensembl:ENSG00000174125|Vega:OTTHUMG00000160413 +7097 TLR2 MIM:603028|HGNC:HGNC:11848|Ensembl:ENSG00000137462|Vega:OTTHUMG00000161525 +7098 TLR3 MIM:603029|HGNC:HGNC:11849|Ensembl:ENSG00000164342|Vega:OTTHUMG00000160345 +7099 TLR4 MIM:603030|HGNC:HGNC:11850|Ensembl:ENSG00000136869|Vega:OTTHUMG00000021046 +7100 TLR5 MIM:603031|HGNC:HGNC:11851|Ensembl:ENSG00000187554|Vega:OTTHUMG00000037937 +7101 NR2E1 MIM:603849|HGNC:HGNC:7973|Ensembl:ENSG00000112333|Vega:OTTHUMG00000015319 +7102 TSPAN7 MIM:300096|HGNC:HGNC:11854|Ensembl:ENSG00000156298|Vega:OTTHUMG00000024090 +7103 TSPAN8 MIM:600769|HGNC:HGNC:11855|Ensembl:ENSG00000127324|Vega:OTTHUMG00000169542 +7104 TM4SF4 MIM:606567|HGNC:HGNC:11856|Ensembl:ENSG00000169903|Vega:OTTHUMG00000159619 +7105 TSPAN6 MIM:300191|HGNC:HGNC:11858|Ensembl:ENSG00000000003|Vega:OTTHUMG00000022002 +7106 TSPAN4 MIM:602644|HGNC:HGNC:11859|Ensembl:ENSG00000214063|Vega:OTTHUMG00000133305 +7107 GPR137B MIM:604658|HGNC:HGNC:11862|Ensembl:ENSG00000077585|Vega:OTTHUMG00000037994 +7108 TM7SF2 MIM:603414|HGNC:HGNC:11863|Ensembl:ENSG00000149809|Vega:OTTHUMG00000165603 +7109 TRAPPC10 MIM:602103|HGNC:HGNC:11868|Ensembl:ENSG00000160218|Vega:OTTHUMG00000086894 +7110 TMF1 MIM:601126|HGNC:HGNC:11870|Ensembl:ENSG00000144747|Vega:OTTHUMG00000158771 +7111 TMOD1 MIM:190930|HGNC:HGNC:11871|Ensembl:ENSG00000136842|Vega:OTTHUMG00000020325 +7112 TMPO MIM:188380|HGNC:HGNC:11875|Ensembl:ENSG00000120802|Vega:OTTHUMG00000170210 +7113 TMPRSS2 MIM:602060|HGNC:HGNC:11876|Ensembl:ENSG00000184012|Vega:OTTHUMG00000086762 +7114 TMSB4X MIM:300159|HGNC:HGNC:11881|Ensembl:ENSG00000205542|Vega:OTTHUMG00000021144 +7115 TMSB4XP1 HGNC:HGNC:11883 +7116 TMSB4XP2 HGNC:HGNC:11884 +7117 TMSB4XP8 HGNC:HGNC:11885 +7118 TMSB4XP4 HGNC:HGNC:11886 +7119 TMSB4XP5 HGNC:HGNC:11887 +7120 TMSB4XP6 HGNC:HGNC:11888 +7121 TMSB4XP7 HGNC:HGNC:11889 +7122 CLDN5 MIM:602101|HGNC:HGNC:2047|Ensembl:ENSG00000184113|Vega:OTTHUMG00000150441 +7123 CLEC3B MIM:187520|HGNC:HGNC:11891|Ensembl:ENSG00000163815|Vega:OTTHUMG00000133087 +7124 TNF MIM:191160|HGNC:HGNC:11892|Ensembl:ENSG00000232810|Vega:OTTHUMG00000031194 +7125 TNNC2 MIM:191039|HGNC:HGNC:11944|Ensembl:ENSG00000101470|Vega:OTTHUMG00000032623 +7126 TNFAIP1 MIM:191161|HGNC:HGNC:11894|Ensembl:ENSG00000109079|Vega:OTTHUMG00000132501 +7127 TNFAIP2 MIM:603300|HGNC:HGNC:11895|Ensembl:ENSG00000185215|Vega:OTTHUMG00000171890 +7128 TNFAIP3 MIM:191163|HGNC:HGNC:11896|Ensembl:ENSG00000118503|Vega:OTTHUMG00000015664 +7130 TNFAIP6 MIM:600410|HGNC:HGNC:11898|Ensembl:ENSG00000123610|Vega:OTTHUMG00000131884 +7132 TNFRSF1A MIM:191190|HGNC:HGNC:11916|Ensembl:ENSG00000067182|Vega:OTTHUMG00000168267 +7133 TNFRSF1B MIM:191191|HGNC:HGNC:11917|Ensembl:ENSG00000028137|Vega:OTTHUMG00000001829 +7134 TNNC1 MIM:191040|HGNC:HGNC:11943|Ensembl:ENSG00000114854|Vega:OTTHUMG00000158572 +7135 TNNI1 MIM:191042|HGNC:HGNC:11945|Ensembl:ENSG00000159173|Vega:OTTHUMG00000035736 +7136 TNNI2 MIM:191043|HGNC:HGNC:11946|Ensembl:ENSG00000130598|Vega:OTTHUMG00000012253 +7137 TNNI3 MIM:191044|HGNC:HGNC:11947|Ensembl:ENSG00000129991|Vega:OTTHUMG00000180589 +7138 TNNT1 MIM:191041|HGNC:HGNC:11948|Ensembl:ENSG00000105048|Vega:OTTHUMG00000180542 +7139 TNNT2 MIM:191045|HGNC:HGNC:11949|Ensembl:ENSG00000118194|Vega:OTTHUMG00000035733 +7140 TNNT3 MIM:600692|HGNC:HGNC:11950|Ensembl:ENSG00000130595|Vega:OTTHUMG00000012475 +7141 TNP1 MIM:190231|HGNC:HGNC:11951|Ensembl:ENSG00000118245|Vega:OTTHUMG00000133057 +7142 TNP2 MIM:190232|HGNC:HGNC:11952|Ensembl:ENSG00000178279|Vega:OTTHUMG00000172315 +7143 TNR MIM:601995|HGNC:HGNC:11953|Ensembl:ENSG00000116147|Vega:OTTHUMG00000034876 +7145 TNS1 MIM:600076|HGNC:HGNC:11973|Ensembl:ENSG00000079308|Vega:OTTHUMG00000133056 +7146 TNXA HGNC:HGNC:11975 +7148 TNXB MIM:600985|HGNC:HGNC:11976|Ensembl:ENSG00000168477|Vega:OTTHUMG00000031088 +7150 TOP1 MIM:126420|HGNC:HGNC:11986|Ensembl:ENSG00000198900|Vega:OTTHUMG00000033057 +7151 TOP1P1 HGNC:HGNC:11987 +7152 TOP1P2 HGNC:HGNC:11988 +7153 TOP2A MIM:126430|HGNC:HGNC:11989|Ensembl:ENSG00000131747|Vega:OTTHUMG00000155008 +7154 TRA-TGC7-1 MIM:601431|HGNC:HGNC:12098 +7155 TOP2B MIM:126431|HGNC:HGNC:11990|Ensembl:ENSG00000077097|Vega:OTTHUMG00000155596 +7156 TOP3A MIM:601243|HGNC:HGNC:11992|Ensembl:ENSG00000177302|Vega:OTTHUMG00000059391 +7157 TP53 MIM:191170|HGNC:HGNC:11998|Ensembl:ENSG00000141510|Vega:OTTHUMG00000162125 +7158 TP53BP1 MIM:605230|HGNC:HGNC:11999|Ensembl:ENSG00000067369|Vega:OTTHUMG00000059757 +7159 TP53BP2 MIM:602143|HGNC:HGNC:12000|Ensembl:ENSG00000143514|Vega:OTTHUMG00000037379 +7161 TP73 MIM:601990|HGNC:HGNC:12003|Ensembl:ENSG00000078900|Vega:OTTHUMG00000000610 +7162 TPBG MIM:190920|HGNC:HGNC:12004|Ensembl:ENSG00000146242|Vega:OTTHUMG00000015103 +7163 TPD52 MIM:604068|HGNC:HGNC:12005|Ensembl:ENSG00000076554|Vega:OTTHUMG00000164565 +7164 TPD52L1 MIM:604069|HGNC:HGNC:12006|Ensembl:ENSG00000111907|Vega:OTTHUMG00000015505 +7165 TPD52L2 MIM:603747|HGNC:HGNC:12007|Ensembl:ENSG00000101150|Vega:OTTHUMG00000033009 +7166 TPH1 MIM:191060|HGNC:HGNC:12008|Ensembl:ENSG00000129167|Vega:OTTHUMG00000166421 +7167 TPI1 MIM:190450|HGNC:HGNC:12009|Ensembl:ENSG00000111669|Vega:OTTHUMG00000133767 +7168 TPM1 MIM:191010|HGNC:HGNC:12010|Ensembl:ENSG00000140416|Vega:OTTHUMG00000132803 +7169 TPM2 MIM:190990|HGNC:HGNC:12011|Ensembl:ENSG00000198467|Vega:OTTHUMG00000019878 +7170 TPM3 MIM:191030|HGNC:HGNC:12012|Ensembl:ENSG00000143549|Vega:OTTHUMG00000035853 +7171 TPM4 MIM:600317|HGNC:HGNC:12013|Ensembl:ENSG00000167460|Vega:OTTHUMG00000182134 +7172 TPMT MIM:187680|HGNC:HGNC:12014|Ensembl:ENSG00000137364|Vega:OTTHUMG00000014317 +7173 TPO MIM:606765|HGNC:HGNC:12015|Ensembl:ENSG00000115705|Vega:OTTHUMG00000090271 +7174 TPP2 MIM:190470|HGNC:HGNC:12016|Ensembl:ENSG00000134900|Vega:OTTHUMG00000017305 +7175 TPR MIM:189940|HGNC:HGNC:12017|Ensembl:ENSG00000047410|Vega:OTTHUMG00000035580 +7177 TPSAB1 MIM:191080|HGNC:HGNC:12019|Ensembl:ENSG00000172236|Vega:OTTHUMG00000090467 +7178 TPT1 MIM:600763|HGNC:HGNC:12022|Ensembl:ENSG00000133112|Vega:OTTHUMG00000016845 +7179 TPTE MIM:604336|HGNC:HGNC:12023|Ensembl:ENSG00000274391|Vega:OTTHUMG00000074127 +7180 CRISP2 MIM:187430|HGNC:HGNC:12024|Ensembl:ENSG00000124490|Vega:OTTHUMG00000014822 +7181 NR2C1 MIM:601529|HGNC:HGNC:7971|Ensembl:ENSG00000120798|Vega:OTTHUMG00000170131 +7182 NR2C2 MIM:601426|HGNC:HGNC:7972|Ensembl:ENSG00000177463|Vega:OTTHUMG00000129839 +7183 TRC-GCA24-1 HGNC:HGNC:12250 +7184 HSP90B1 MIM:191175|HGNC:HGNC:12028|Ensembl:ENSG00000166598|Vega:OTTHUMG00000170118 +7185 TRAF1 MIM:601711|HGNC:HGNC:12031|Ensembl:ENSG00000056558|Vega:OTTHUMG00000020578 +7186 TRAF2 MIM:601895|HGNC:HGNC:12032|Ensembl:ENSG00000127191|Vega:OTTHUMG00000020952 +7187 TRAF3 MIM:601896|HGNC:HGNC:12033|Ensembl:ENSG00000131323|Vega:OTTHUMG00000171902 +7188 TRAF5 MIM:602356|HGNC:HGNC:12035|Ensembl:ENSG00000082512|Vega:OTTHUMG00000036997 +7189 TRAF6 MIM:602355|HGNC:HGNC:12036|Ensembl:ENSG00000175104|Vega:OTTHUMG00000166391 +7190 HSP90B2P HGNC:HGNC:12099|Ensembl:ENSG00000259706 +7192 TRD-GTC9-1 HGNC:HGNC:12251 +7193 TRE-TTC3-1 MIM:180640|HGNC:HGNC:12265 +7195 TRNAG1 MIM:189911 +7196 TRG-GCC2-6 MIM:610407|HGNC:HGNC:12273 +7197 TRG-TCC1-1 MIM:615303|HGNC:HGNC:12274 +7198 TRG-GCC3-1 HGNC:HGNC:12282 +7200 TRH MIM:613879|HGNC:HGNC:12298|Ensembl:ENSG00000170893|Vega:OTTHUMG00000159634 +7201 TRHR MIM:188545|HGNC:HGNC:12299|Ensembl:ENSG00000174417|Vega:OTTHUMG00000164910 +7202 TRI-AAT9-1 HGNC:HGNC:12300 +7203 CCT3 MIM:600114|HGNC:HGNC:1616|Ensembl:ENSG00000163468|Vega:OTTHUMG00000024061 +7204 TRIO MIM:601893|HGNC:HGNC:12303|Ensembl:ENSG00000038382|Vega:OTTHUMG00000131057 +7205 TRIP6 MIM:602933|HGNC:HGNC:12311|Ensembl:ENSG00000087077|Vega:OTTHUMG00000157029 +7206 TRK-TTT3-5 MIM:189918|HGNC:HGNC:12314 +7207 TRL-AAG2-3 MIM:189932|HGNC:HGNC:12315 +7208 TRL-TAG1-1 MIM:189920|HGNC:HGNC:12316 +7209 TRNAL47P - +7210 TRX-CAT1-2 MIM:180621|HGNC:HGNC:12318 +7211 TRMEP1 HGNC:HGNC:12321 +7212 TRX-CAT2-1 MIM:180620|HGNC:HGNC:12322 +7214 TRN-GTT2-1 MIM:189880|HGNC:HGNC:12324 +7216 TRO MIM:300132|HGNC:HGNC:12326|Ensembl:ENSG00000067445|Vega:OTTHUMG00000021640 +7217 TRP-AGG2-5 MIM:189930|HGNC:HGNC:12330 +7218 TRP-AGG2-6 MIM:189931|HGNC:HGNC:12331 +7219 TRP-TGG3-1 MIM:189912|HGNC:HGNC:12332 +7220 TRPC1 MIM:602343|HGNC:HGNC:12333|Ensembl:ENSG00000144935|Vega:OTTHUMG00000159301 +7221 TRPC2 HGNC:HGNC:12334|Ensembl:ENSG00000182048 +7222 TRPC3 MIM:602345|HGNC:HGNC:12335|Ensembl:ENSG00000138741|Vega:OTTHUMG00000133069 +7223 TRPC4 MIM:603651|HGNC:HGNC:12336|Ensembl:ENSG00000133107|Vega:OTTHUMG00000016752 +7224 TRPC5 MIM:300334|HGNC:HGNC:12337|Ensembl:ENSG00000072315|Vega:OTTHUMG00000022212 +7225 TRPC6 MIM:603652|HGNC:HGNC:12338|Ensembl:ENSG00000137672|Vega:OTTHUMG00000167483 +7226 TRPM2 MIM:603749|HGNC:HGNC:12339|Ensembl:ENSG00000142185|Vega:OTTHUMG00000040840 +7227 TRPS1 MIM:604386|HGNC:HGNC:12340|Ensembl:ENSG00000104447|Vega:OTTHUMG00000142829 +7228 TRQ-CTG1-5 MIM:189919|HGNC:HGNC:12341 +7229 TRQ-TTG1-1 MIM:189923|HGNC:HGNC:12342 +7230 TRR-TCT2-1 MIM:610406|HGNC:HGNC:12343 +7231 TRR-ACG1-2 MIM:615305|HGNC:HGNC:12344 +7232 TRR-TCG4-1 MIM:601432|HGNC:HGNC:12345 +7233 TRR-CCG2-1 HGNC:HGNC:12346 +7234 TRU-TCA1-1 MIM:165060|HGNC:HGNC:12348 +7235 TRU-TCA2-1 HGNC:HGNC:12349 +7236 TRT-TGT6-1 MIM:189913|HGNC:HGNC:12350 +7237 TRT-TGT3-1 MIM:189933|HGNC:HGNC:12351 +7238 TRT-AGT7-1 HGNC:HGNC:12352 +7239 TRV-AAC1-4 MIM:189921|HGNC:HGNC:12353 +7240 TRV-CAC1-2 MIM:612995|HGNC:HGNC:12354 +7241 TRV-AAC1-3 HGNC:HGNC:12355 +7246 TRW-CCA7-1 HGNC:HGNC:12360 +7247 TSN MIM:600575|HGNC:HGNC:12379|Ensembl:ENSG00000211460|Vega:OTTHUMG00000153334 +7248 TSC1 MIM:605284|HGNC:HGNC:12362|Ensembl:ENSG00000165699|Vega:OTTHUMG00000020844 +7249 TSC2 MIM:191092|HGNC:HGNC:12363|Ensembl:ENSG00000103197|Vega:OTTHUMG00000128745 +7251 TSG101 MIM:601387|HGNC:HGNC:15971|Ensembl:ENSG00000074319|Vega:OTTHUMG00000167725 +7252 TSHB MIM:188540|HGNC:HGNC:12372|Ensembl:ENSG00000134200|Vega:OTTHUMG00000011881 +7253 TSHR MIM:603372|HGNC:HGNC:12373|Ensembl:ENSG00000165409|Vega:OTTHUMG00000171429 +7254 TSHRL1 HGNC:HGNC:12374 +7255 TSHRL2 HGNC:HGNC:12375 +7256 TSHRL3 HGNC:HGNC:12376 +7257 TSNAX MIM:602964|HGNC:HGNC:12380|Ensembl:ENSG00000116918|Vega:OTTHUMG00000039486 +7258 TSPY1 MIM:480100|HGNC:HGNC:12381|Ensembl:ENSG00000258992|Vega:OTTHUMG00000171452 +7259 TSPYL1 MIM:604714|HGNC:HGNC:12382|Ensembl:ENSG00000189241|Vega:OTTHUMG00000015427 +7260 EIPR1 MIM:608998|HGNC:HGNC:12383|Ensembl:ENSG00000032389|Vega:OTTHUMG00000090329 +7262 PHLDA2 MIM:602131|HGNC:HGNC:12385|Ensembl:ENSG00000181649|Vega:OTTHUMG00000010926 +7263 TST MIM:180370|HGNC:HGNC:12388|Ensembl:ENSG00000128311|Vega:OTTHUMG00000150533 +7264 TSTA3 MIM:137020|HGNC:HGNC:12390|Ensembl:ENSG00000104522|Vega:OTTHUMG00000165159 +7265 TTC1 MIM:601963|HGNC:HGNC:12391|Ensembl:ENSG00000113312|Vega:OTTHUMG00000130326 +7266 DNAJC7 MIM:601964|HGNC:HGNC:12392|Ensembl:ENSG00000168259|Vega:OTTHUMG00000180862 +7267 TTC3 MIM:602259|HGNC:HGNC:12393|Ensembl:ENSG00000182670|Vega:OTTHUMG00000086654 +7268 TTC4 MIM:606753|HGNC:HGNC:12394|Ensembl:ENSG00000243725|Vega:OTTHUMG00000009914 +7270 TTF1 MIM:600777|HGNC:HGNC:12397|Ensembl:ENSG00000125482|Vega:OTTHUMG00000020836 +7272 TTK MIM:604092|HGNC:HGNC:12401|Ensembl:ENSG00000112742|Vega:OTTHUMG00000015088 +7273 TTN MIM:188840|HGNC:HGNC:12403|Ensembl:ENSG00000155657|Vega:OTTHUMG00000154448 +7274 TTPA MIM:600415|HGNC:HGNC:12404|Ensembl:ENSG00000137561|Vega:OTTHUMG00000164367 +7275 TUB MIM:601197|HGNC:HGNC:12406|Ensembl:ENSG00000166402|Vega:OTTHUMG00000165690 +7276 TTR MIM:176300|HGNC:HGNC:12405|Ensembl:ENSG00000118271|Vega:OTTHUMG00000131984 +7277 TUBA4A MIM:191110|HGNC:HGNC:12407|Ensembl:ENSG00000127824|Vega:OTTHUMG00000133126 +7278 TUBA3C MIM:602528|HGNC:HGNC:12408|Ensembl:ENSG00000198033|Vega:OTTHUMG00000016481 +7280 TUBB2A MIM:615101|HGNC:HGNC:12412|Ensembl:ENSG00000137267|Vega:OTTHUMG00000014135 +7283 TUBG1 MIM:191135|HGNC:HGNC:12417|Ensembl:ENSG00000131462|Vega:OTTHUMG00000180277 +7284 TUFM MIM:602389|HGNC:HGNC:12420|Ensembl:ENSG00000178952|Vega:OTTHUMG00000097039 +7286 TUFT1 MIM:600087|HGNC:HGNC:12422|Ensembl:ENSG00000143367|Vega:OTTHUMG00000012536 +7287 TULP1 MIM:602280|HGNC:HGNC:12423|Ensembl:ENSG00000112041|Vega:OTTHUMG00000014575 +7288 TULP2 MIM:602309|HGNC:HGNC:12424|Ensembl:ENSG00000104804|Vega:OTTHUMG00000164406 +7289 TULP3 MIM:604730|HGNC:HGNC:12425|Ensembl:ENSG00000078246|Vega:OTTHUMG00000168152 +7290 HIRA MIM:600237|HGNC:HGNC:4916|Ensembl:ENSG00000100084|Vega:OTTHUMG00000150134 +7291 TWIST1 MIM:601622|HGNC:HGNC:12428|Ensembl:ENSG00000122691|Vega:OTTHUMG00000090821 +7292 TNFSF4 MIM:603594|HGNC:HGNC:11934|Ensembl:ENSG00000117586|Vega:OTTHUMG00000034838 +7293 TNFRSF4 MIM:600315|HGNC:HGNC:11918|Ensembl:ENSG00000186827|Vega:OTTHUMG00000001415 +7294 TXK MIM:600058|HGNC:HGNC:12434|Ensembl:ENSG00000074966|Vega:OTTHUMG00000102065 +7295 TXN MIM:187700|HGNC:HGNC:12435|Ensembl:ENSG00000136810|Vega:OTTHUMG00000020480 +7296 TXNRD1 MIM:601112|HGNC:HGNC:12437|Ensembl:ENSG00000198431|Vega:OTTHUMG00000166481 +7297 TYK2 MIM:176941|HGNC:HGNC:12440|Ensembl:ENSG00000105397|Vega:OTTHUMG00000166373 +7298 TYMS MIM:188350|HGNC:HGNC:12441|Ensembl:ENSG00000176890|Vega:OTTHUMG00000131473 +7299 TYR MIM:606933|HGNC:HGNC:12442|Ensembl:ENSG00000077498|Vega:OTTHUMG00000167294 +7300 TYRL MIM:191270|HGNC:HGNC:12443 +7301 TYRO3 MIM:600341|HGNC:HGNC:12446|Ensembl:ENSG00000092445|Vega:OTTHUMG00000130341 +7302 TYRO3P HGNC:HGNC:12447 +7303 TYS MIM:181600|HGNC:HGNC:12452 +7305 TYROBP MIM:604142|HGNC:HGNC:12449|Ensembl:ENSG00000011600|Vega:OTTHUMG00000181739 +7306 TYRP1 MIM:115501|HGNC:HGNC:12450|Ensembl:ENSG00000107165|Vega:OTTHUMG00000021034 +7307 U2AF1 MIM:191317|HGNC:HGNC:12453|Ensembl:ENSG00000160201|Vega:OTTHUMG00000086836 +7310 ZRSR1 MIM:601079|HGNC:HGNC:12456 +7311 UBA52 MIM:191321|HGNC:HGNC:12458|Ensembl:ENSG00000221983|Vega:OTTHUMG00000183110 +7312 UBA52P1 HGNC:HGNC:12459 +7313 UBA52P2 HGNC:HGNC:12460 +7314 UBB MIM:191339|HGNC:HGNC:12463|Ensembl:ENSG00000170315|Vega:OTTHUMG00000058987 +7315 UBBP1 HGNC:HGNC:12464 +7316 UBC MIM:191340|HGNC:HGNC:12468|Ensembl:ENSG00000150991|Vega:OTTHUMG00000044421 +7317 UBA1 MIM:314370|HGNC:HGNC:12469|Ensembl:ENSG00000130985|Vega:OTTHUMG00000021436 +7318 UBA7 MIM:191325|HGNC:HGNC:12471|Ensembl:ENSG00000182179|Vega:OTTHUMG00000158267 +7319 UBE2A MIM:312180|HGNC:HGNC:12472|Ensembl:ENSG00000077721|Vega:OTTHUMG00000022275 +7320 UBE2B MIM:179095|HGNC:HGNC:12473|Ensembl:ENSG00000119048|Vega:OTTHUMG00000129120 +7321 UBE2D1 MIM:602961|HGNC:HGNC:12474|Ensembl:ENSG00000072401|Vega:OTTHUMG00000018269 +7322 UBE2D2 MIM:602962|HGNC:HGNC:12475|Ensembl:ENSG00000131508|Vega:OTTHUMG00000163282 +7323 UBE2D3 MIM:602963|HGNC:HGNC:12476|Ensembl:ENSG00000109332|Vega:OTTHUMG00000131119 +7324 UBE2E1 MIM:602916|HGNC:HGNC:12477|Ensembl:ENSG00000170142|Vega:OTTHUMG00000130483 +7325 UBE2E2 MIM:602163|HGNC:HGNC:12478|Ensembl:ENSG00000182247|Vega:OTTHUMG00000130482 +7326 UBE2G1 MIM:601569|HGNC:HGNC:12482|Ensembl:ENSG00000132388|Vega:OTTHUMG00000177826 +7327 UBE2G2 MIM:603124|HGNC:HGNC:12483|Ensembl:ENSG00000184787|Vega:OTTHUMG00000089179 +7328 UBE2H MIM:601082|HGNC:HGNC:12484|Ensembl:ENSG00000186591|Vega:OTTHUMG00000157650 +7329 UBE2I MIM:601661|HGNC:HGNC:12485|Ensembl:ENSG00000103275|Vega:OTTHUMG00000186701 +7332 UBE2L3 MIM:603721|HGNC:HGNC:12488|Ensembl:ENSG00000185651|Vega:OTTHUMG00000150823 +7333 UBE2L4 HGNC:HGNC:12489 +7334 UBE2N MIM:603679|HGNC:HGNC:12492|Ensembl:ENSG00000177889|Vega:OTTHUMG00000170156 +7335 UBE2V1 MIM:602995|HGNC:HGNC:12494|Ensembl:ENSG00000244687|Vega:OTTHUMG00000152626 +7336 UBE2V2 MIM:603001|HGNC:HGNC:12495|Ensembl:ENSG00000169139|Vega:OTTHUMG00000164206 +7337 UBE3A MIM:601623|HGNC:HGNC:12496|Ensembl:ENSG00000114062|Vega:OTTHUMG00000171548 +7338 UBE3AP1 HGNC:HGNC:12497 +7339 UBE3AP2 HGNC:HGNC:12498 +7341 SUMO1 MIM:601912|HGNC:HGNC:12502|Ensembl:ENSG00000116030|Vega:OTTHUMG00000132839 +7342 UBP1 MIM:609784|HGNC:HGNC:12507|Ensembl:ENSG00000153560|Vega:OTTHUMG00000130749 +7343 UBTF MIM:600673|HGNC:HGNC:12511|Ensembl:ENSG00000108312|Vega:OTTHUMG00000167585 +7345 UCHL1 MIM:191342|HGNC:HGNC:12513|Ensembl:ENSG00000154277|Vega:OTTHUMG00000099377 +7347 UCHL3 MIM:603090|HGNC:HGNC:12515|Ensembl:ENSG00000118939|Vega:OTTHUMG00000017090 +7348 UPK1B MIM:602380|HGNC:HGNC:12578|Ensembl:ENSG00000114638|Vega:OTTHUMG00000159354 +7349 UCN MIM:600945|HGNC:HGNC:12516|Ensembl:ENSG00000163794|Vega:OTTHUMG00000097068 +7350 UCP1 MIM:113730|HGNC:HGNC:12517|Ensembl:ENSG00000109424|Vega:OTTHUMG00000133415 +7351 UCP2 MIM:601693|HGNC:HGNC:12518|Ensembl:ENSG00000175567|Vega:OTTHUMG00000168095 +7352 UCP3 MIM:602044|HGNC:HGNC:12519|Ensembl:ENSG00000175564|Vega:OTTHUMG00000168109 +7353 UFD1 MIM:601754|HGNC:HGNC:12520|Ensembl:ENSG00000070010|Vega:OTTHUMG00000150130 +7355 SLC35A2 MIM:314375|HGNC:HGNC:11022|Ensembl:ENSG00000102100|Vega:OTTHUMG00000024129 +7356 SCGB1A1 MIM:192020|HGNC:HGNC:12523|Ensembl:ENSG00000149021|Vega:OTTHUMG00000167526 +7357 UGCG MIM:602874|HGNC:HGNC:12524|Ensembl:ENSG00000148154|Vega:OTTHUMG00000020498 +7358 UGDH MIM:603370|HGNC:HGNC:12525|Ensembl:ENSG00000109814|Vega:OTTHUMG00000099371 +7360 UGP2 MIM:191760|HGNC:HGNC:12527|Ensembl:ENSG00000169764|Vega:OTTHUMG00000129513 +7361 UGT1A HGNC:HGNC:12529 +7363 UGT2B4 MIM:600067|HGNC:HGNC:12553|Ensembl:ENSG00000156096|Vega:OTTHUMG00000058891 +7364 UGT2B7 MIM:600068|HGNC:HGNC:12554|Ensembl:ENSG00000171234|Vega:OTTHUMG00000129404 +7365 UGT2B10 MIM:600070|HGNC:HGNC:12544|Ensembl:ENSG00000109181|Vega:OTTHUMG00000161505 +7366 UGT2B15 MIM:600069|HGNC:HGNC:12546|Ensembl:ENSG00000196620|Vega:OTTHUMG00000161507 +7367 UGT2B17 MIM:601903|HGNC:HGNC:12547|Ensembl:ENSG00000197888|Vega:OTTHUMG00000129305 +7368 UGT8 MIM:601291|HGNC:HGNC:12555|Ensembl:ENSG00000174607|Vega:OTTHUMG00000132915 +7369 UMOD MIM:191845|HGNC:HGNC:12559|Ensembl:ENSG00000169344|Vega:OTTHUMG00000131488 +7371 UCK2 MIM:609329|HGNC:HGNC:12562|Ensembl:ENSG00000143179|Vega:OTTHUMG00000040117 +7372 UMPS MIM:613891|HGNC:HGNC:12563|Ensembl:ENSG00000114491|Vega:OTTHUMG00000159431 +7373 COL14A1 MIM:120324|HGNC:HGNC:2191|Ensembl:ENSG00000187955|Vega:OTTHUMG00000149877 +7374 UNG MIM:191525|HGNC:HGNC:12572|Ensembl:ENSG00000076248|Vega:OTTHUMG00000169247 +7375 USP4 MIM:603486|HGNC:HGNC:12627|Ensembl:ENSG00000114316|Vega:OTTHUMG00000156825 +7376 NR1H2 MIM:600380|HGNC:HGNC:7965|Ensembl:ENSG00000131408|Vega:OTTHUMG00000183036 +7378 UPP1 MIM:191730|HGNC:HGNC:12576|Ensembl:ENSG00000183696|Vega:OTTHUMG00000129253 +7379 UPK2 MIM:611558|HGNC:HGNC:12579|Ensembl:ENSG00000110375|Vega:OTTHUMG00000166346 +7380 UPK3A MIM:611559|HGNC:HGNC:12580|Ensembl:ENSG00000100373|Vega:OTTHUMG00000151339 +7381 UQCRB MIM:191330|HGNC:HGNC:12582|Ensembl:ENSG00000156467|Vega:OTTHUMG00000164711 +7384 UQCRC1 MIM:191328|HGNC:HGNC:12585|Ensembl:ENSG00000010256|Vega:OTTHUMG00000133539 +7385 UQCRC2 MIM:191329|HGNC:HGNC:12586|Ensembl:ENSG00000140740|Vega:OTTHUMG00000131585 +7386 UQCRFS1 MIM:191327|HGNC:HGNC:12587|Ensembl:ENSG00000169021|Vega:OTTHUMG00000181997 +7388 UQCRH MIM:613844|HGNC:HGNC:12590|Ensembl:ENSG00000173660|Vega:OTTHUMG00000007813 +7389 UROD MIM:613521|HGNC:HGNC:12591|Ensembl:ENSG00000126088|Vega:OTTHUMG00000008949 +7390 UROS MIM:606938|HGNC:HGNC:12592|Ensembl:ENSG00000188690|Vega:OTTHUMG00000019236 +7391 USF1 MIM:191523|HGNC:HGNC:12593|Ensembl:ENSG00000158773|Vega:OTTHUMG00000031472 +7392 USF2 MIM:600390|HGNC:HGNC:12594|Ensembl:ENSG00000105698|Vega:OTTHUMG00000183182 +7396 USH1E MIM:602097|HGNC:HGNC:12599 +7398 USP1 MIM:603478|HGNC:HGNC:12607|Ensembl:ENSG00000162607|Vega:OTTHUMG00000008972 +7399 USH2A MIM:608400|HGNC:HGNC:12601|Ensembl:ENSG00000042781|Vega:OTTHUMG00000037079 +7401 CLRN1 MIM:606397|HGNC:HGNC:12605|Ensembl:ENSG00000163646|Vega:OTTHUMG00000140368 +7402 UTRN MIM:128240|HGNC:HGNC:12635|Ensembl:ENSG00000152818|Vega:OTTHUMG00000015746 +7403 KDM6A MIM:300128|HGNC:HGNC:12637|Ensembl:ENSG00000147050|Vega:OTTHUMG00000021402 +7404 UTY MIM:400009|HGNC:HGNC:12638|Ensembl:ENSG00000183878|Vega:OTTHUMG00000036319 +7405 UVRAG MIM:602493|HGNC:HGNC:12640|Ensembl:ENSG00000198382|Vega:OTTHUMG00000165319 +7407 VARS MIM:192150|HGNC:HGNC:12651|Ensembl:ENSG00000204394|Vega:OTTHUMG00000031286 +7408 VASP MIM:601703|HGNC:HGNC:12652|Ensembl:ENSG00000125753|Vega:OTTHUMG00000182124 +7409 VAV1 MIM:164875|HGNC:HGNC:12657|Ensembl:ENSG00000141968|Vega:OTTHUMG00000181965 +7410 VAV2 MIM:600428|HGNC:HGNC:12658|Ensembl:ENSG00000160293|Vega:OTTHUMG00000020882 +7411 VBP1 MIM:300133|HGNC:HGNC:12662|Ensembl:ENSG00000155959|Vega:OTTHUMG00000022666 +7412 VCAM1 MIM:192225|HGNC:HGNC:12663|Ensembl:ENSG00000162692|Vega:OTTHUMG00000010982 +7414 VCL MIM:193065|HGNC:HGNC:12665|Ensembl:ENSG00000035403|Vega:OTTHUMG00000018498 +7415 VCP MIM:601023|HGNC:HGNC:12666|Ensembl:ENSG00000165280|Vega:OTTHUMG00000019855 +7416 VDAC1 MIM:604492|HGNC:HGNC:12669|Ensembl:ENSG00000213585|Vega:OTTHUMG00000129118 +7417 VDAC2 MIM:193245|HGNC:HGNC:12672|Ensembl:ENSG00000165637|Vega:OTTHUMG00000018517 +7418 VDAC1P4 MIM:610030|HGNC:HGNC:12675 +7419 VDAC3 MIM:610029|HGNC:HGNC:12674|Ensembl:ENSG00000078668|Vega:OTTHUMG00000164168 +7420 VDI MIM:125260|HGNC:HGNC:12678 +7421 VDR MIM:601769|HGNC:HGNC:12679|Ensembl:ENSG00000111424|Vega:OTTHUMG00000169890 +7422 VEGFA MIM:192240|HGNC:HGNC:12680|Ensembl:ENSG00000112715|Vega:OTTHUMG00000014745 +7423 VEGFB MIM:601398|HGNC:HGNC:12681|Ensembl:ENSG00000173511|Vega:OTTHUMG00000167813 +7424 VEGFC MIM:601528|HGNC:HGNC:12682|Ensembl:ENSG00000150630|Vega:OTTHUMG00000160734 +7425 VGF MIM:602186|HGNC:HGNC:12684|Ensembl:ENSG00000128564|Vega:OTTHUMG00000157109 +7428 VHL MIM:608537|HGNC:HGNC:12687|Ensembl:ENSG00000134086|Vega:OTTHUMG00000128668 +7429 VIL1 MIM:193040|HGNC:HGNC:12690|Ensembl:ENSG00000127831|Vega:OTTHUMG00000133112 +7430 EZR MIM:123900|HGNC:HGNC:12691|Ensembl:ENSG00000092820|Vega:OTTHUMG00000015917 +7431 VIM MIM:193060|HGNC:HGNC:12692|Ensembl:ENSG00000026025|Vega:OTTHUMG00000017744 +7432 VIP MIM:192320|HGNC:HGNC:12693|Ensembl:ENSG00000146469|Vega:OTTHUMG00000015851 +7433 VIPR1 MIM:192321|HGNC:HGNC:12694|Ensembl:ENSG00000114812|Vega:OTTHUMG00000131792 +7434 VIPR2 MIM:601970|HGNC:HGNC:12695|Ensembl:ENSG00000106018|Vega:OTTHUMG00000151446 +7435 VIS1 MIM:164755|HGNC:HGNC:12696 +7436 VLDLR MIM:192977|HGNC:HGNC:12698|Ensembl:ENSG00000147852|Vega:OTTHUMG00000019447 +7438 VMD1 MIM:153840|HGNC:HGNC:12702 +7439 BEST1 MIM:607854|HGNC:HGNC:12703|Ensembl:ENSG00000167995|Vega:OTTHUMG00000167469 +7441 VPREB1 MIM:605141|HGNC:HGNC:12709|Ensembl:ENSG00000169575|IMGT/GENE-DB:VPREB1|Vega:OTTHUMG00000151042 +7442 TRPV1 MIM:602076|HGNC:HGNC:12716|Ensembl:ENSG00000196689|Vega:OTTHUMG00000177649 +7443 VRK1 MIM:602168|HGNC:HGNC:12718|Ensembl:ENSG00000100749|Vega:OTTHUMG00000171459 +7444 VRK2 MIM:602169|HGNC:HGNC:12719|Ensembl:ENSG00000028116|Vega:OTTHUMG00000129348 +7446 AVSD1 MIM:606215|HGNC:HGNC:12721 +7447 VSNL1 MIM:600817|HGNC:HGNC:12722|Ensembl:ENSG00000163032|Vega:OTTHUMG00000090645 +7448 VTN MIM:193190|HGNC:HGNC:12724|Ensembl:ENSG00000109072|Vega:OTTHUMG00000132500 +7450 VWF MIM:613160|HGNC:HGNC:12726|Ensembl:ENSG00000110799|Vega:OTTHUMG00000168265 +7451 VWFP1 HGNC:HGNC:12727 +7453 WARS MIM:191050|HGNC:HGNC:12729|Ensembl:ENSG00000140105|Vega:OTTHUMG00000171572 +7454 WAS MIM:300392|HGNC:HGNC:12731|Ensembl:ENSG00000015285|Vega:OTTHUMG00000034483 +7455 ZAN MIM:602372|HGNC:HGNC:12857|Ensembl:ENSG00000146839|Vega:OTTHUMG00000157037 +7456 WIPF1 MIM:602357|HGNC:HGNC:12736|Ensembl:ENSG00000115935|Vega:OTTHUMG00000132334 +7457 WBS2 HGNC:HGNC:12740 +7458 EIF4H MIM:603431|HGNC:HGNC:12741|Ensembl:ENSG00000106682|Vega:OTTHUMG00000023025 +7459 WBSCR2 HGNC:HGNC:12746 +7461 CLIP2 MIM:603432|HGNC:HGNC:2586|Ensembl:ENSG00000106665|Vega:OTTHUMG00000022980 +7462 LAT2 MIM:605719|HGNC:HGNC:12749|Ensembl:ENSG00000086730|Vega:OTTHUMG00000130151 +7464 CORO2A MIM:602159|HGNC:HGNC:2255|Ensembl:ENSG00000106789|Vega:OTTHUMG00000020340 +7465 WEE1 MIM:193525|HGNC:HGNC:12761|Ensembl:ENSG00000166483|Vega:OTTHUMG00000165863 +7466 WFS1 MIM:606201|HGNC:HGNC:12762|Ensembl:ENSG00000109501|Vega:OTTHUMG00000090431 +7467 WHCR MIM:194190|HGNC:HGNC:12764 +7468 NSD2 MIM:602952|HGNC:HGNC:12766|Ensembl:ENSG00000109685|Vega:OTTHUMG00000121147 +7469 NELFA MIM:606026|HGNC:HGNC:12768|Ensembl:ENSG00000185049|Vega:OTTHUMG00000089967 +7471 WNT1 MIM:164820|HGNC:HGNC:12774|Ensembl:ENSG00000125084|Vega:OTTHUMG00000170403 +7472 WNT2 MIM:147870|HGNC:HGNC:12780|Ensembl:ENSG00000105989|Vega:OTTHUMG00000023428 +7473 WNT3 MIM:165330|HGNC:HGNC:12782|Ensembl:ENSG00000108379|Vega:OTTHUMG00000178076 +7474 WNT5A MIM:164975|HGNC:HGNC:12784|Ensembl:ENSG00000114251|Vega:OTTHUMG00000158361 +7475 WNT6 MIM:604663|HGNC:HGNC:12785|Ensembl:ENSG00000115596|Vega:OTTHUMG00000133082 +7476 WNT7A MIM:601570|HGNC:HGNC:12786|Ensembl:ENSG00000154764|Vega:OTTHUMG00000129803 +7477 WNT7B MIM:601967|HGNC:HGNC:12787|Ensembl:ENSG00000188064|Vega:OTTHUMG00000154636 +7478 WNT8A MIM:606360|HGNC:HGNC:12788|Ensembl:ENSG00000061492|Vega:OTTHUMG00000129196 +7479 WNT8B MIM:601396|HGNC:HGNC:12789|Ensembl:ENSG00000075290|Vega:OTTHUMG00000018912 +7480 WNT10B MIM:601906|HGNC:HGNC:12775|Ensembl:ENSG00000169884|Vega:OTTHUMG00000150734 +7481 WNT11 MIM:603699|HGNC:HGNC:12776|Ensembl:ENSG00000085741|Vega:OTTHUMG00000165264 +7482 WNT2B MIM:601968|HGNC:HGNC:12781|Ensembl:ENSG00000134245|Vega:OTTHUMG00000011157 +7483 WNT9A MIM:602863|HGNC:HGNC:12778|Ensembl:ENSG00000143816|Vega:OTTHUMG00000037592 +7484 WNT9B MIM:602864|HGNC:HGNC:12779|Ensembl:ENSG00000158955|Vega:OTTHUMG00000178077 +7485 WRB MIM:602915|HGNC:HGNC:12790|Ensembl:ENSG00000182093|Vega:OTTHUMG00000066250 +7486 WRN MIM:604611|HGNC:HGNC:12791|Ensembl:ENSG00000165392|Vega:OTTHUMG00000163894 +7488 WS2B MIM:600193|HGNC:HGNC:12794 +7489 WSN MIM:311510|HGNC:HGNC:12795 +7490 WT1 MIM:607102|HGNC:HGNC:12796|Ensembl:ENSG00000184937|Vega:OTTHUMG00000039556 +7491 WT2 MIM:194071|HGNC:HGNC:12797 +7494 XBP1 MIM:194355|HGNC:HGNC:12801|Ensembl:ENSG00000100219|Vega:OTTHUMG00000151094 +7495 XBP1P1 HGNC:HGNC:12802 +7497 XCE MIM:300074|HGNC:HGNC:12804 +7498 XDH MIM:607633|HGNC:HGNC:12805|Ensembl:ENSG00000158125|Vega:OTTHUMG00000099385 +7499 XG MIM:300879|HGNC:HGNC:12806|Ensembl:ENSG00000124343|Vega:OTTHUMG00000021075 +7500 XGY1 HGNC:HGNC:12807 +7501 XGR MIM:314705|MIM:489500|HGNC:HGNC:12808 +7502 XIC HGNC:HGNC:12809 +7503 XIST MIM:314670|HGNC:HGNC:12810|Ensembl:ENSG00000229807 +7504 XK MIM:314850|HGNC:HGNC:12811|Ensembl:ENSG00000047597|Vega:OTTHUMG00000033171 +7506 XM MIM:314900|HGNC:HGNC:12813 +7507 XPA MIM:611153|HGNC:HGNC:12814|Ensembl:ENSG00000136936|Vega:OTTHUMG00000020330 +7508 XPC MIM:613208|HGNC:HGNC:12816|Ensembl:ENSG00000154767|Vega:OTTHUMG00000155526 +7511 XPNPEP1 MIM:602443|HGNC:HGNC:12822|Ensembl:ENSG00000108039|Vega:OTTHUMG00000019029 +7512 XPNPEP2 MIM:300145|HGNC:HGNC:12823|Ensembl:ENSG00000122121|Vega:OTTHUMG00000022373 +7514 XPO1 MIM:602559|HGNC:HGNC:12825|Ensembl:ENSG00000082898|Vega:OTTHUMG00000152316 +7515 XRCC1 MIM:194360|HGNC:HGNC:12828|Ensembl:ENSG00000073050|Vega:OTTHUMG00000182699 +7516 XRCC2 MIM:600375|HGNC:HGNC:12829|Ensembl:ENSG00000196584|Vega:OTTHUMG00000151470 +7517 XRCC3 MIM:600675|HGNC:HGNC:12830|Ensembl:ENSG00000126215|Vega:OTTHUMG00000169228 +7518 XRCC4 MIM:194363|HGNC:HGNC:12831|Ensembl:ENSG00000152422|Vega:OTTHUMG00000131319 +7520 XRCC5 MIM:194364|HGNC:HGNC:12833|Ensembl:ENSG00000079246|Vega:OTTHUMG00000133059 +7521 XRCC8 HGNC:HGNC:12834 +7523 XS MIM:309050|HGNC:HGNC:12837 +7524 XWNPEP HGNC:HGNC:12838 +7525 YES1 MIM:164880|HGNC:HGNC:12841|Ensembl:ENSG00000176105|Vega:OTTHUMG00000131472 +7526 YES1P1 HGNC:HGNC:12842 +7528 YY1 MIM:600013|HGNC:HGNC:12856|Ensembl:ENSG00000100811|Vega:OTTHUMG00000150479 +7529 YWHAB MIM:601289|HGNC:HGNC:12849|Ensembl:ENSG00000166913|Vega:OTTHUMG00000032549 +7531 YWHAE MIM:605066|HGNC:HGNC:12851|Ensembl:ENSG00000108953|Vega:OTTHUMG00000134316 +7532 YWHAG MIM:605356|HGNC:HGNC:12852|Ensembl:ENSG00000170027|Vega:OTTHUMG00000022862 +7533 YWHAH MIM:113508|HGNC:HGNC:12853|Ensembl:ENSG00000128245|Vega:OTTHUMG00000030833 +7534 YWHAZ MIM:601288|HGNC:HGNC:12855|Ensembl:ENSG00000164924|Vega:OTTHUMG00000134291 +7535 ZAP70 MIM:176947|HGNC:HGNC:12858|Ensembl:ENSG00000115085|Vega:OTTHUMG00000153060 +7536 SF1 MIM:601516|HGNC:HGNC:12950|Ensembl:ENSG00000168066|Vega:OTTHUMG00000066833 +7538 ZFP36 MIM:190700|HGNC:HGNC:12862|Ensembl:ENSG00000128016|Vega:OTTHUMG00000182970 +7539 ZFP37 MIM:602951|HGNC:HGNC:12863|Ensembl:ENSG00000136866|Vega:OTTHUMG00000021019 +7541 ZBTB14 MIM:602126|HGNC:HGNC:12860|Ensembl:ENSG00000198081|Vega:OTTHUMG00000131563 +7542 ZFPL1 HGNC:HGNC:12868|Ensembl:ENSG00000162300|Vega:OTTHUMG00000165597 +7543 ZFX MIM:314980|HGNC:HGNC:12869|Ensembl:ENSG00000005889|Vega:OTTHUMG00000021264 +7544 ZFY MIM:490000|HGNC:HGNC:12870|Ensembl:ENSG00000067646|Vega:OTTHUMG00000036159 +7545 ZIC1 MIM:600470|HGNC:HGNC:12872|Ensembl:ENSG00000152977|Vega:OTTHUMG00000159456 +7546 ZIC2 MIM:603073|HGNC:HGNC:12873|Ensembl:ENSG00000043355|Vega:OTTHUMG00000017279 +7547 ZIC3 MIM:300265|HGNC:HGNC:12874|Ensembl:ENSG00000156925|Vega:OTTHUMG00000022525 +7549 ZNF2 MIM:194500|HGNC:HGNC:12991|Ensembl:ENSG00000275111|Vega:OTTHUMG00000155150 +7551 ZNF3 MIM:194510|HGNC:HGNC:13089|Ensembl:ENSG00000166526|Vega:OTTHUMG00000154596 +7552 ZNF711 MIM:314990|HGNC:HGNC:13128|Ensembl:ENSG00000147180|Vega:OTTHUMG00000021933 +7553 ZNF7 MIM:194531|HGNC:HGNC:13139|Ensembl:ENSG00000147789|Vega:OTTHUMG00000165200 +7554 ZNF8 MIM:194532|HGNC:HGNC:13154|Ensembl:ENSG00000278129|Vega:OTTHUMG00000182073 +7555 CNBP MIM:116955|HGNC:HGNC:13164|Ensembl:ENSG00000169714|Vega:OTTHUMG00000159943 +7556 ZNF10 MIM:194538|HGNC:HGNC:12879|Ensembl:ENSG00000256223|Vega:OTTHUMG00000167944 +7559 ZNF12 MIM:194536|HGNC:HGNC:12902|Ensembl:ENSG00000164631|Vega:OTTHUMG00000151910 +7561 ZNF14 MIM:194556|HGNC:HGNC:12924|Ensembl:ENSG00000105708|Vega:OTTHUMG00000182362 +7562 ZNF708 HGNC:HGNC:12945|Ensembl:ENSG00000182141|Vega:OTTHUMG00000182841 +7564 ZNF16 MIM:601262|HGNC:HGNC:12947|Ensembl:ENSG00000170631|Vega:OTTHUMG00000165253 +7565 ZNF17 HGNC:HGNC:12958|Ensembl:ENSG00000186272|Vega:OTTHUMG00000183371 +7566 ZNF18 MIM:194524|HGNC:HGNC:12969|Ensembl:ENSG00000154957|Vega:OTTHUMG00000178307 +7567 ZNF19 MIM:194525|HGNC:HGNC:12981|Ensembl:ENSG00000157429|Vega:OTTHUMG00000137593 +7568 ZNF20 MIM:194557|HGNC:HGNC:12992|Ensembl:ENSG00000132010|Vega:OTTHUMG00000156409 +7569 ZNF182 MIM:314993|HGNC:HGNC:13001|Ensembl:ENSG00000147118|Vega:OTTHUMG00000021460 +7570 ZNF22 MIM:194529|HGNC:HGNC:13012|Ensembl:ENSG00000165512|Vega:OTTHUMG00000018064 +7571 ZNF23 MIM:194527|HGNC:HGNC:13023|Ensembl:ENSG00000167377|Vega:OTTHUMG00000176797 +7572 ZNF24 MIM:194534|HGNC:HGNC:13032|Ensembl:ENSG00000172466|Vega:OTTHUMG00000132565 +7574 ZNF26 MIM:194537|HGNC:HGNC:13053|Ensembl:ENSG00000198393|Vega:OTTHUMG00000167936 +7576 ZNF28 HGNC:HGNC:13073|Ensembl:ENSG00000198538|Vega:OTTHUMG00000154564 +7577 ZNF29P MIM:194535|HGNC:HGNC:13080 +7579 ZSCAN20 MIM:611315|HGNC:HGNC:13093|Ensembl:ENSG00000121903|Vega:OTTHUMG00000004173 +7580 ZNF32 MIM:194539|HGNC:HGNC:13095|Ensembl:ENSG00000169740|Vega:OTTHUMG00000018043 +7581 ZNF33A MIM:194521|HGNC:HGNC:13096|Ensembl:ENSG00000189180|Vega:OTTHUMG00000017983 +7582 ZNF33B MIM:194522|HGNC:HGNC:13097|Ensembl:ENSG00000196693|Vega:OTTHUMG00000018014 +7584 ZNF35 MIM:194533|HGNC:HGNC:13099|Ensembl:ENSG00000169981|Vega:OTTHUMG00000133091 +7586 ZKSCAN1 MIM:601260|HGNC:HGNC:13101|Ensembl:ENSG00000106261|Vega:OTTHUMG00000156534 +7587 ZNF37A MIM:616085|HGNC:HGNC:13102|Ensembl:ENSG00000075407|Vega:OTTHUMG00000191777 +7589 ZSCAN21 MIM:601261|HGNC:HGNC:13104|Ensembl:ENSG00000166529|Vega:OTTHUMG00000154583 +7592 ZNF41 MIM:314995|HGNC:HGNC:13107|Ensembl:ENSG00000147124|Vega:OTTHUMG00000021448 +7593 MZF1 MIM:194550|HGNC:HGNC:13108|Ensembl:ENSG00000099326|Vega:OTTHUMG00000183550 +7594 ZNF43 MIM:603972|HGNC:HGNC:13109|Ensembl:ENSG00000198521|Vega:OTTHUMG00000128543 +7596 ZNF45 MIM:194554|HGNC:HGNC:13111|Ensembl:ENSG00000124459|Vega:OTTHUMG00000182189 +7597 ZBTB25 MIM:194541|HGNC:HGNC:13112|Ensembl:ENSG00000089775|Vega:OTTHUMG00000141310 +7608 ZNF56 HGNC:HGNC:13124 +7617 ZNF66 HGNC:HGNC:13135 +7618 ZNF726P1 HGNC:HGNC:13136 +7620 ZNF69 MIM:194543|HGNC:HGNC:13138|Ensembl:ENSG00000198429|Vega:OTTHUMG00000156526 +7621 ZNF70 MIM:194544|HGNC:HGNC:13140|Ensembl:ENSG00000187792|Vega:OTTHUMG00000150739 +7625 ZNF74 MIM:194548|HGNC:HGNC:13144|Ensembl:ENSG00000185252|Vega:OTTHUMG00000150687 +7626 ZNF75D MIM:314997|HGNC:HGNC:13145|Ensembl:ENSG00000186376|Vega:OTTHUMG00000022482 +7627 ZNF75A MIM:601473|HGNC:HGNC:13146|Ensembl:ENSG00000162086|Vega:OTTHUMG00000129356 +7628 ZNF75BP HGNC:HGNC:13147 +7629 ZNF76 MIM:194549|HGNC:HGNC:13149|Ensembl:ENSG00000065029|Vega:OTTHUMG00000014564 +7633 ZNF79 MIM:194552|HGNC:HGNC:13153|Ensembl:ENSG00000196152|Vega:OTTHUMG00000020703 +7634 ZNF80 MIM:194553|HGNC:HGNC:13155|Ensembl:ENSG00000174255|Vega:OTTHUMG00000159332 +7637 ZNF84 HGNC:HGNC:13159|Ensembl:ENSG00000198040|Vega:OTTHUMG00000167939 +7638 ZNF221 HGNC:HGNC:13014|Ensembl:ENSG00000159905|Vega:OTTHUMG00000182214 +7639 ZNF85 MIM:603899|HGNC:HGNC:13160|Ensembl:ENSG00000105750|Vega:OTTHUMG00000182747 +7643 ZNF90 MIM:603973|HGNC:HGNC:13165|Ensembl:ENSG00000213988|Vega:OTTHUMG00000158057 +7644 ZNF91 MIM:603971|HGNC:HGNC:13166|Ensembl:ENSG00000167232|Vega:OTTHUMG00000183268 +7652 ZNF99 MIM:603981|HGNC:HGNC:13175|Ensembl:ENSG00000213973|Vega:OTTHUMG00000182992 +7661 ZNF90P1 HGNC:HGNC:12888 +7673 ZNF222 MIM:617357|HGNC:HGNC:13015|Ensembl:ENSG00000159885|Vega:OTTHUMG00000182309 +7675 ZNF121 MIM:194628|HGNC:HGNC:12904|Ensembl:ENSG00000197961|Vega:OTTHUMG00000180134 +7678 ZNF124 MIM:194631|HGNC:HGNC:12907|Ensembl:ENSG00000196418|Vega:OTTHUMG00000041112 +7681 MKRN3 MIM:603856|HGNC:HGNC:7114|Ensembl:ENSG00000179455|Vega:OTTHUMG00000129160 +7682 MKRN4P HGNC:HGNC:7115 +7683 MKRN5P HGNC:HGNC:7117 +7686 MKRN7P HGNC:HGNC:7119|Ensembl:ENSG00000225849 +7690 ZNF131 MIM:604073|HGNC:HGNC:12915|Ensembl:ENSG00000172262|Vega:OTTHUMG00000162223 +7691 ZNF132 MIM:604074|HGNC:HGNC:12916|Ensembl:ENSG00000131849|Vega:OTTHUMG00000183537 +7692 ZNF133 MIM:604075|HGNC:HGNC:12917|Ensembl:ENSG00000125846|Vega:OTTHUMG00000031965 +7693 ZNF134 MIM:604076|HGNC:HGNC:12918|Ensembl:ENSG00000213762|Vega:OTTHUMG00000183471 +7694 ZNF135 MIM:604077|HGNC:HGNC:12919|Ensembl:ENSG00000176293|Vega:OTTHUMG00000160719 +7695 ZNF136 MIM:604078|HGNC:HGNC:12920|Ensembl:ENSG00000196646|Vega:OTTHUMG00000156429 +7696 ZNF137P MIM:604079|HGNC:HGNC:12921 +7697 ZNF138 MIM:604080|HGNC:HGNC:12922|Ensembl:ENSG00000197008|Vega:OTTHUMG00000156603 +7699 ZNF140 MIM:604082|HGNC:HGNC:12925|Ensembl:ENSG00000196387|Vega:OTTHUMG00000167942 +7700 ZNF141 MIM:194648|HGNC:HGNC:12926|Ensembl:ENSG00000131127|Vega:OTTHUMG00000159852 +7701 ZNF142 MIM:604083|HGNC:HGNC:12927|Ensembl:ENSG00000115568|Vega:OTTHUMG00000154736 +7702 ZNF143 MIM:603433|HGNC:HGNC:12928|Ensembl:ENSG00000166478|Vega:OTTHUMG00000149922 +7703 PCGF2 MIM:600346|HGNC:HGNC:12929|Ensembl:ENSG00000277258|Vega:OTTHUMG00000188501 +7704 ZBTB16 MIM:176797|HGNC:HGNC:12930|Ensembl:ENSG00000109906|Vega:OTTHUMG00000168243 +7705 ZNF146 MIM:601505|HGNC:HGNC:12931|Ensembl:ENSG00000167635|Vega:OTTHUMG00000180511 +7706 TRIM25 MIM:600453|HGNC:HGNC:12932|Ensembl:ENSG00000121060|Vega:OTTHUMG00000178124 +7707 ZNF148 MIM:601897|HGNC:HGNC:12933|Ensembl:ENSG00000163848|Vega:OTTHUMG00000159448 +7709 ZBTB17 MIM:604084|HGNC:HGNC:12936|Ensembl:ENSG00000116809|Vega:OTTHUMG00000009377 +7710 ZNF154 MIM:604085|HGNC:HGNC:12939|Ensembl:ENSG00000179909|Vega:OTTHUMG00000140375 +7711 ZNF155 MIM:604086|HGNC:HGNC:12940|Ensembl:ENSG00000204920|Vega:OTTHUMG00000182215 +7712 ZNF157 MIM:300024|HGNC:HGNC:12942|Ensembl:ENSG00000147117|Vega:OTTHUMG00000021443 +7716 VEZF1 MIM:606747|HGNC:HGNC:12949|Ensembl:ENSG00000136451|Vega:OTTHUMG00000178777 +7718 ZNF165 MIM:600834|HGNC:HGNC:12953|Ensembl:ENSG00000197279|Vega:OTTHUMG00000014505 +7726 TRIM26 MIM:600830|HGNC:HGNC:12962|Ensembl:ENSG00000234127|Vega:OTTHUMG00000031041 +7727 ZNF174 MIM:603900|HGNC:HGNC:12963|Ensembl:ENSG00000103343|Vega:OTTHUMG00000129358 +7728 ZNF175 MIM:601139|HGNC:HGNC:12964|Ensembl:ENSG00000105497|Vega:OTTHUMG00000167771 +7730 ZNF177 MIM:601276|HGNC:HGNC:12966|Ensembl:ENSG00000188629|Ensembl:ENSG00000270011|Vega:OTTHUMG00000179943 +7732 RNF112 MIM:601237|HGNC:HGNC:12968|Ensembl:ENSG00000128482|Vega:OTTHUMG00000059601 +7733 ZNF180 MIM:606740|HGNC:HGNC:12970|Ensembl:ENSG00000167384|Vega:OTTHUMG00000180495 +7737 RNF113A MIM:300951|HGNC:HGNC:12974|Ensembl:ENSG00000125352|Vega:OTTHUMG00000022283 +7738 ZNF184 MIM:602277|HGNC:HGNC:12975|Ensembl:ENSG00000096654|Vega:OTTHUMG00000014478 +7739 ZNF185 MIM:300381|HGNC:HGNC:12976|Ensembl:ENSG00000147394|Vega:OTTHUMG00000024187 +7741 ZSCAN26 MIM:616474|HGNC:HGNC:12978|Ensembl:ENSG00000197062|Vega:OTTHUMG00000014519 +7743 ZNF189 MIM:603132|HGNC:HGNC:12980|Ensembl:ENSG00000136870|Vega:OTTHUMG00000020383 +7745 ZKSCAN8 MIM:602240|HGNC:HGNC:12983|Ensembl:ENSG00000198315|Vega:OTTHUMG00000014510 +7746 ZSCAN9 MIM:602246|HGNC:HGNC:12984|Ensembl:ENSG00000137185|Vega:OTTHUMG00000014515 +7748 ZNF195 MIM:602187|HGNC:HGNC:12986|Ensembl:ENSG00000005801|Vega:OTTHUMG00000011694 +7750 ZMYM2 MIM:602221|HGNC:HGNC:12989|Ensembl:ENSG00000121741|Vega:OTTHUMG00000016507 +7752 ZNF200 MIM:603231|HGNC:HGNC:12993|Ensembl:ENSG00000010539|Vega:OTTHUMG00000129317 +7753 ZNF202 MIM:603430|HGNC:HGNC:12994|Ensembl:ENSG00000166261|Vega:OTTHUMG00000166008 +7754 ZNF204P MIM:603282|HGNC:HGNC:12995 +7755 ZNF205 MIM:603436|HGNC:HGNC:12996|Ensembl:ENSG00000122386|Vega:OTTHUMG00000148676 +7756 ZNF207 MIM:603428|HGNC:HGNC:12998|Ensembl:ENSG00000010244|Vega:OTTHUMG00000132810 +7757 ZNF208 MIM:603977|HGNC:HGNC:12999|Ensembl:ENSG00000160321|Vega:OTTHUMG00000182913 +7760 ZNF213 MIM:608387|HGNC:HGNC:13005|Ensembl:ENSG00000085644|Vega:OTTHUMG00000177519 +7761 ZNF214 MIM:605015|HGNC:HGNC:13006|Ensembl:ENSG00000149050|Vega:OTTHUMG00000165618 +7762 ZNF215 MIM:605016|HGNC:HGNC:13007|Ensembl:ENSG00000149054|Vega:OTTHUMG00000165507 +7763 ZFAND5 MIM:604761|HGNC:HGNC:13008|Ensembl:ENSG00000107372|Vega:OTTHUMG00000020008 +7764 ZNF217 MIM:602967|HGNC:HGNC:13009|Ensembl:ENSG00000171940|Vega:OTTHUMG00000032764 +7766 ZNF223 HGNC:HGNC:13016|Ensembl:ENSG00000178386|Vega:OTTHUMG00000182311 +7767 ZNF224 MIM:194555|HGNC:HGNC:13017|Ensembl:ENSG00000267680|Vega:OTTHUMG00000182313 +7768 ZNF225 HGNC:HGNC:13018|Ensembl:ENSG00000256294|Vega:OTTHUMG00000182336 +7769 ZNF226 HGNC:HGNC:13019|Ensembl:ENSG00000167380|Vega:OTTHUMG00000182351 +7770 ZNF227 HGNC:HGNC:13020|Ensembl:ENSG00000131115|Vega:OTTHUMG00000182352 +7771 ZNF112 MIM:603994|HGNC:HGNC:12892|Ensembl:ENSG00000062370|Vega:OTTHUMG00000182357 +7772 ZNF229 HGNC:HGNC:13022|Ensembl:ENSG00000278318|Vega:OTTHUMG00000182377 +7773 ZNF230 HGNC:HGNC:13024|Ensembl:ENSG00000159882|Vega:OTTHUMG00000182307 +7775 ZNF232 MIM:616463|HGNC:HGNC:13026|Ensembl:ENSG00000167840|Vega:OTTHUMG00000099450 +7776 ZNF236 MIM:604760|HGNC:HGNC:13028|Ensembl:ENSG00000130856|Vega:OTTHUMG00000179331 +7779 SLC30A1 MIM:609521|HGNC:HGNC:11012|Ensembl:ENSG00000170385|Vega:OTTHUMG00000036995 +7780 SLC30A2 MIM:609617|HGNC:HGNC:11013|Ensembl:ENSG00000158014|Vega:OTTHUMG00000007508 +7781 SLC30A3 MIM:602878|HGNC:HGNC:11014|Ensembl:ENSG00000115194|Vega:OTTHUMG00000128409 +7782 SLC30A4 MIM:602095|HGNC:HGNC:11015|Ensembl:ENSG00000104154|Vega:OTTHUMG00000131439 +7783 ZP2 MIM:182888|HGNC:HGNC:13188|Ensembl:ENSG00000103310|Vega:OTTHUMG00000090681 +7784 ZP3 MIM:182889|HGNC:HGNC:13189|Ensembl:ENSG00000188372|Vega:OTTHUMG00000130575 +7786 MAP3K12 MIM:600447|HGNC:HGNC:6851|Ensembl:ENSG00000139625|Vega:OTTHUMG00000169854 +7789 ZXDA MIM:300235|HGNC:HGNC:13198|Ensembl:ENSG00000198205|Vega:OTTHUMG00000021688 +7791 ZYX MIM:602002|HGNC:HGNC:13200|Ensembl:ENSG00000159840|Vega:OTTHUMG00000023822 +7792 CCV MIM:115665|HGNC:HGNC:1624 +7795 MEMO1 MIM:601201 +7798 LUZP1 MIM:601422|HGNC:HGNC:14985|Ensembl:ENSG00000169641|Vega:OTTHUMG00000003227 +7799 PRDM2 MIM:601196|HGNC:HGNC:9347|Ensembl:ENSG00000116731|Vega:OTTHUMG00000007917 +7802 DNALI1 MIM:602135|HGNC:HGNC:14353|Ensembl:ENSG00000163879|Vega:OTTHUMG00000004222 +7803 PTP4A1 MIM:601585|HGNC:HGNC:9634|Ensembl:ENSG00000112245|Vega:OTTHUMG00000014949 +7804 LRP8 MIM:602600|HGNC:HGNC:6700|Ensembl:ENSG00000157193|Vega:OTTHUMG00000008924 +7805 LAPTM5 MIM:601476|HGNC:HGNC:29612|Ensembl:ENSG00000162511|Vega:OTTHUMG00000003707 +7808 AIR MIM:601676 +7809 BSND MIM:606412|HGNC:HGNC:16512|Ensembl:ENSG00000162399|Vega:OTTHUMG00000008112 +7812 CSDE1 MIM:191510|HGNC:HGNC:29905|Ensembl:ENSG00000009307|Vega:OTTHUMG00000012060 +7813 EVI5 MIM:602942|HGNC:HGNC:3501|Ensembl:ENSG00000067208|Vega:OTTHUMG00000010895 +7818 DAP3 MIM:602074|HGNC:HGNC:2673|Ensembl:ENSG00000132676|Vega:OTTHUMG00000035439 +7824 D1S111 MIM:157560 +7827 NPHS2 MIM:604766|HGNC:HGNC:13394|Ensembl:ENSG00000116218|Vega:OTTHUMG00000035252 +7830 PHA2A MIM:145260 +7832 BTG2 MIM:601597|HGNC:HGNC:1131|Ensembl:ENSG00000159388|Vega:OTTHUMG00000035834 +7834 PCAP MIM:602759|HGNC:HGNC:8645 +7837 PXDN MIM:605158|HGNC:HGNC:14966|Ensembl:ENSG00000130508|Vega:OTTHUMG00000059697 +7839 LEPQTL1 MIM:601694 +7840 ALMS1 MIM:606844|HGNC:HGNC:428|Ensembl:ENSG00000116127|Vega:OTTHUMG00000152812 +7841 MOGS MIM:601336|HGNC:HGNC:24862|Ensembl:ENSG00000115275|Vega:OTTHUMG00000152886 +7842 IGKJ MIM:146970 +7844 RNF103 MIM:602507|HGNC:HGNC:12859|Ensembl:ENSG00000239305|Vega:OTTHUMG00000153197 +7845 PAFAH1B1P1 HGNC:HGNC:8577 +7846 TUBA1A MIM:602529|HGNC:HGNC:20766|Ensembl:ENSG00000167552|Vega:OTTHUMG00000169511 +7849 PAX8 MIM:167415|HGNC:HGNC:8622|Ensembl:ENSG00000125618|Vega:OTTHUMG00000128529 +7850 IL1R2 MIM:147811|HGNC:HGNC:5994|Ensembl:ENSG00000115590|Vega:OTTHUMG00000130695 +7851 MALL MIM:602022|HGNC:HGNC:6818|Ensembl:ENSG00000144063|Vega:OTTHUMG00000131196 +7852 CXCR4 MIM:162643|HGNC:HGNC:2561|Ensembl:ENSG00000121966|Vega:OTTHUMG00000153583 +7855 FZD5 MIM:601723|HGNC:HGNC:4043|Ensembl:ENSG00000163251|Vega:OTTHUMG00000154790 +7857 SCG2 MIM:118930|HGNC:HGNC:10575|Ensembl:ENSG00000171951|Vega:OTTHUMG00000133166 +7862 BRPF1 MIM:602410|HGNC:HGNC:14255|Ensembl:ENSG00000156983|Vega:OTTHUMG00000097033 +7864 SCLC1 MIM:182280 +7866 IFRD2 MIM:602725|HGNC:HGNC:5457|Ensembl:ENSG00000214706|Vega:OTTHUMG00000156935 +7867 MAPKAPK3 MIM:602130|HGNC:HGNC:6888|Ensembl:ENSG00000114738|Vega:OTTHUMG00000156850 +7869 SEMA3B MIM:601281|HGNC:HGNC:10724|Ensembl:ENSG00000012171|Vega:OTTHUMG00000156970 +7870 TRR MIM:601994 +7871 SLMAP MIM:602701|HGNC:HGNC:16643|Ensembl:ENSG00000163681|Vega:OTTHUMG00000133764 +7873 MANF MIM:601916|HGNC:HGNC:15461|Ensembl:ENSG00000145050|Vega:OTTHUMG00000156897 +7874 USP7 MIM:602519|HGNC:HGNC:12630|Ensembl:ENSG00000187555|Vega:OTTHUMG00000176903 +7879 RAB7A MIM:602298|HGNC:HGNC:9788|Ensembl:ENSG00000075785|Vega:OTTHUMG00000159812 +7880 MBS2 MIM:601471|HGNC:HGNC:6927 +7881 KCNAB1 MIM:601141|HGNC:HGNC:6228|Ensembl:ENSG00000169282|Vega:OTTHUMG00000158552 +7884 SLBP MIM:602422|HGNC:HGNC:10904|Ensembl:ENSG00000163950|Vega:OTTHUMG00000089349 +7885 CRSA MIM:600593 +7889 PSORS3 MIM:601454|HGNC:HGNC:9575 +7892 FECB MIM:134720 +7895 LAG5 MIM:151450 +7896 TS13 MIM:187320 +7897 ZNF4 - +7900 ZNF5 - +7903 ST8SIA4 MIM:602547|HGNC:HGNC:10871|Ensembl:ENSG00000113532|Vega:OTTHUMG00000128727 +7905 REEP5 MIM:125265|HGNC:HGNC:30077|Ensembl:ENSG00000129625|Vega:OTTHUMG00000128807 +7908 EOS MIM:131400 +7909 HEMC MIM:602089 +7910 PFBI MIM:248310 +7911 SM1 MIM:181460 +7913 DEK MIM:125264|HGNC:HGNC:2768|Ensembl:ENSG00000124795|Vega:OTTHUMG00000014319 +7915 ALDH5A1 MIM:610045|HGNC:HGNC:408|Ensembl:ENSG00000112294|Vega:OTTHUMG00000014356 +7916 PRRC2A MIM:142580|HGNC:HGNC:13918|Ensembl:ENSG00000204469|Vega:OTTHUMG00000031168 +7917 BAG6 MIM:142590|HGNC:HGNC:13919|Ensembl:ENSG00000204463|Vega:OTTHUMG00000031171 +7918 GPANK1 MIM:142610|HGNC:HGNC:13920|Ensembl:ENSG00000204438|Vega:OTTHUMG00000031174 +7919 DDX39B MIM:142560|HGNC:HGNC:13917|Ensembl:ENSG00000198563|Vega:OTTHUMG00000031165 +7920 ABHD16A MIM:142620|HGNC:HGNC:13921|Ensembl:ENSG00000204427|Vega:OTTHUMG00000031177 +7921 D6S207E - +7922 SLC39A7 MIM:601416|HGNC:HGNC:4927|Ensembl:ENSG00000112473|Vega:OTTHUMG00000031238 +7923 HSD17B8 MIM:601417|HGNC:HGNC:3554|Ensembl:ENSG00000204228|Vega:OTTHUMG00000031117 +7925 IGLP1 MIM:147080|HGNC:HGNC:5873 +7926 IGLP2 MIM:147090|HGNC:HGNC:5874 +7927 IGAT MIM:146820 +7928 ISCW MIM:146850 +7932 OR2H2 MIM:600578|HGNC:HGNC:8253|Ensembl:ENSG00000204657|Vega:OTTHUMG00000031052 +7933 OPLL MIM:602475 +7936 NELFE MIM:154040|HGNC:HGNC:13974|Ensembl:ENSG00000204356|Vega:OTTHUMG00000031046 +7937 RWS MIM:179450 +7938 CP20 MIM:153380 +7939 LAP MIM:150270 +7940 LST1 MIM:109170|HGNC:HGNC:14189|Ensembl:ENSG00000204482|Vega:OTTHUMG00000031264 +7941 PLA2G7 MIM:601690|HGNC:HGNC:9040|Ensembl:ENSG00000146070|Vega:OTTHUMG00000014789 +7942 TFEB MIM:600744|HGNC:HGNC:11753|Ensembl:ENSG00000112561|Vega:OTTHUMG00000014684 +7944 CSCI MIM:122550 +7945 PUJO MIM:143400 +7948 PBCRA1 MIM:600790|HGNC:HGNC:8625 +7951 BKMA1 MIM:109780 +7952 TNDM - +7954 HBFQTL2 MIM:142470 +7955 RNF217-AS1 MIM:602532|HGNC:HGNC:50866|Ensembl:ENSG00000236548 +7956 NTT MIM:602154 +7957 EPM2A MIM:607566|HGNC:HGNC:3413|Ensembl:ENSG00000112425|Vega:OTTHUMG00000015747 +7959 FEA MIM:137010 +7960 MRBC MIM:158050 +7962 PBCA MIM:600089 +7963 TS546 MIM:187330 +7965 AIMP2 MIM:600859|HGNC:HGNC:20609|Ensembl:ENSG00000106305|Vega:OTTHUMG00000122077 +7971 GHS MIM:141400 +7974 HRX MIM:145290 +7975 MAFK MIM:600197|HGNC:HGNC:6782|Ensembl:ENSG00000198517|Vega:OTTHUMG00000151453 +7976 FZD3 MIM:606143|HGNC:HGNC:4041|Ensembl:ENSG00000104290|Vega:OTTHUMG00000102145 +7977 MHS3 MIM:154276 +7978 MTERF1 MIM:602318|HGNC:HGNC:21463|Ensembl:ENSG00000127989|Vega:OTTHUMG00000156057 +7979 SEM1 MIM:601285|HGNC:HGNC:10845|Ensembl:ENSG00000127922|Vega:OTTHUMG00000150680 +7980 TFPI2 MIM:600033|HGNC:HGNC:11761|Ensembl:ENSG00000105825|Vega:OTTHUMG00000022963 +7982 ST7 MIM:600833|HGNC:HGNC:11351|Ensembl:ENSG00000004866|Vega:OTTHUMG00000023888 +7984 ARHGEF5 MIM:600888|HGNC:HGNC:13209|Ensembl:ENSG00000050327|Vega:OTTHUMG00000158004 +7986 GPDS1 MIM:600510|HGNC:HGNC:4457 +7988 ZNF212 MIM:602386|HGNC:HGNC:13004|Ensembl:ENSG00000170260|Vega:OTTHUMG00000158968 +7990 CRS1C - +7991 TUSC3 MIM:601385|HGNC:HGNC:30242|Ensembl:ENSG00000104723|Vega:OTTHUMG00000094803 +7993 UBXN8 MIM:602155|HGNC:HGNC:30307|Ensembl:ENSG00000104691|Vega:OTTHUMG00000163851 +7994 KAT6A MIM:601408|HGNC:HGNC:13013|Ensembl:ENSG00000083168|Vega:OTTHUMG00000150453 +8000 PSCA MIM:602470|HGNC:HGNC:9500|Ensembl:ENSG00000167653|Vega:OTTHUMG00000162077 +8001 GLRA3 MIM:600421|HGNC:HGNC:4328|Ensembl:ENSG00000145451|Vega:OTTHUMG00000149816 +8009 LALL MIM:247640 +8011 MROS MIM:155900|HGNC:HGNC:14595 +8013 NR4A3 MIM:600542|HGNC:HGNC:7982|Ensembl:ENSG00000119508|Vega:OTTHUMG00000021030 +8019 BRD3 MIM:601541|HGNC:HGNC:1104|Ensembl:ENSG00000169925|Vega:OTTHUMG00000021004 +8021 NUP214 MIM:114350|HGNC:HGNC:8064|Ensembl:ENSG00000126883|Vega:OTTHUMG00000020816 +8022 LHX3 MIM:600577|HGNC:HGNC:6595|Ensembl:ENSG00000107187|Vega:OTTHUMG00000020924 +8023 H142T MIM:187290 +8024 RDPA MIM:600964 +8026 DGS2 MIM:601362 +8027 STAM MIM:601899|HGNC:HGNC:11357|Ensembl:ENSG00000136738|Vega:OTTHUMG00000017749 +8028 MLLT10 MIM:602409|HGNC:HGNC:16063|Ensembl:ENSG00000078403|Vega:OTTHUMG00000017799 +8029 CUBN MIM:602997|HGNC:HGNC:2548|Ensembl:ENSG00000107611|Vega:OTTHUMG00000017741 +8030 CCDC6 MIM:601985|HGNC:HGNC:18782|Ensembl:ENSG00000108091|Vega:OTTHUMG00000018284 +8031 NCOA4 MIM:601984|HGNC:HGNC:7671|Ensembl:ENSG00000266412|Vega:OTTHUMG00000188314 +8034 SLC25A16 MIM:139080|HGNC:HGNC:10986|Ensembl:ENSG00000122912|Vega:OTTHUMG00000018354 +8036 SHOC2 MIM:602775|HGNC:HGNC:15454|Ensembl:ENSG00000108061|Vega:OTTHUMG00000019047 +8038 ADAM12 MIM:602714|HGNC:HGNC:190|Ensembl:ENSG00000148848|Vega:OTTHUMG00000019243 +8039 PROA MIM:176770 +8041 TP250 MIM:186710 +8045 RASSF7 MIM:143023|HGNC:HGNC:1166|Ensembl:ENSG00000099849|Vega:OTTHUMG00000132004 +8048 CSRP3 MIM:600824|HGNC:HGNC:2472|Ensembl:ENSG00000129170|Vega:OTTHUMG00000166100 +8050 PDHX MIM:608769|HGNC:HGNC:21350|Ensembl:ENSG00000110435|Vega:OTTHUMG00000166491 +8056 ECB2 MIM:263400 +8060 FNL2 MIM:135610 +8061 FOSL1 MIM:136515|HGNC:HGNC:13718|Ensembl:ENSG00000175592|Vega:OTTHUMG00000166715 +8065 CUL5 MIM:601741|HGNC:HGNC:2556|Ensembl:ENSG00000166266|Vega:OTTHUMG00000166369 +8066 ANC MIM:105580 +8068 BRCATA MIM:600048 +8073 PTP4A2 MIM:601584|HGNC:HGNC:9635|Ensembl:ENSG00000184007|Vega:OTTHUMG00000003801 +8074 FGF23 MIM:605380|HGNC:HGNC:3680|Ensembl:ENSG00000118972|Vega:OTTHUMG00000168241 +8075 PCS MIM:168710 +8076 MFAP5 MIM:601103|HGNC:HGNC:29673|Ensembl:ENSG00000197614|Vega:OTTHUMG00000168703 +8078 USP5 MIM:601447|HGNC:HGNC:12628|Ensembl:ENSG00000111667|Vega:OTTHUMG00000169233 +8079 MLF2 MIM:601401|HGNC:HGNC:7126|Ensembl:ENSG00000089693|Vega:OTTHUMG00000168717 +8080 HTNB MIM:112410 +8081 AD5 MIM:602096|HGNC:HGNC:185 +8082 SSPN MIM:601599|HGNC:HGNC:11322|Ensembl:ENSG00000123096|Vega:OTTHUMG00000169167 +8083 KAR MIM:107920 +8085 KMT2D MIM:602113|HGNC:HGNC:7133|Ensembl:ENSG00000167548|Vega:OTTHUMG00000166524 +8086 AAAS MIM:605378|HGNC:HGNC:13666|Ensembl:ENSG00000094914|Vega:OTTHUMG00000169729 +8087 FXR1 MIM:600819|HGNC:HGNC:4023|Ensembl:ENSG00000114416|Vega:OTTHUMG00000158138 +8089 YEATS4 MIM:602116|HGNC:HGNC:24859|Ensembl:ENSG00000127337|Vega:OTTHUMG00000169358 +8090 SPPM MIM:181430 +8091 HMGA2 MIM:600698|HGNC:HGNC:5009|Ensembl:ENSG00000149948|Vega:OTTHUMG00000168936 +8092 ALX1 MIM:601527|HGNC:HGNC:1494|Ensembl:ENSG00000180318|Vega:OTTHUMG00000169820 +8093 MGCT MIM:273300 +8094 SMAL MIM:600175 +8099 CDK2AP1 MIM:602198|HGNC:HGNC:14002|Ensembl:ENSG00000111328|Vega:OTTHUMG00000168854 +8100 IFT88 MIM:600595|HGNC:HGNC:20606|Ensembl:ENSG00000032742|Vega:OTTHUMG00000016517 +8101 CLLS2 MIM:109543 +8102 XRS MIM:194370 +8103 PAPA2 MIM:602085 +8104 MCOR MIM:156600 +8105 BRCD1 MIM:114450 +8106 PABPN1 MIM:602279|HGNC:HGNC:8565|Ensembl:ENSG00000100836|Vega:OTTHUMG00000028739 +8110 DPF3 MIM:601672|HGNC:HGNC:17427|Ensembl:ENSG00000205683|Vega:OTTHUMG00000171364 +8111 GPR68 MIM:601404|HGNC:HGNC:4519|Ensembl:ENSG00000119714|Vega:OTTHUMG00000167590 +8113 MCOP1 MIM:251600 +8114 IV MIM:270100|HGNC:HGNC:6185 +8115 TCL1A MIM:186960|HGNC:HGNC:11648|Ensembl:ENSG00000100721|Vega:OTTHUMG00000171390 +8118 LCH MIM:151020 +8120 AP3B2 MIM:602166|HGNC:HGNC:567|Ensembl:ENSG00000103723|Vega:OTTHUMG00000168009 +8123 PWAR5 MIM:600162|HGNC:HGNC:30090|Ensembl:ENSG00000279192 +8125 ANP32A MIM:600832|HGNC:HGNC:13233|Ensembl:ENSG00000140350|Vega:OTTHUMG00000154502 +8126 MRST MIM:602685 +8128 ST8SIA2 MIM:602546|HGNC:HGNC:10870|Ensembl:ENSG00000140557|Vega:OTTHUMG00000149843 +8129 HBHR MIM:141750 +8130 MCOPCT1 MIM:156850 +8131 NPRL3 MIM:600928|HGNC:HGNC:14124|Ensembl:ENSG00000103148|Vega:OTTHUMG00000047792 +8132 PKDTS MIM:600273 +8136 WT3 MIM:194090 +8137 HYD2 MIM:602639|HGNC:HGNC:13822 +8139 GAN MIM:605379|HGNC:HGNC:4137|Ensembl:ENSG00000261609|Vega:OTTHUMG00000137627 +8140 SLC7A5 MIM:600182|HGNC:HGNC:11063|Ensembl:ENSG00000103257|Vega:OTTHUMG00000137658 +8142 BCPR MIM:113721 +8144 CMS1A1 MIM:605809 +8148 TAF15 MIM:601574|HGNC:HGNC:11547|Ensembl:ENSG00000270647|Vega:OTTHUMG00000188384 +8151 WT4 MIM:601363 +8153 RND2 MIM:601555|HGNC:HGNC:18315|Ensembl:ENSG00000108830|Vega:OTTHUMG00000180817 +8156 GPSC MIM:221820 +8160 MVWF - +8161 COIL MIM:600272|HGNC:HGNC:2184|Ensembl:ENSG00000121058|Vega:OTTHUMG00000178126 +8163 CDR3 MIM:602197 +8165 AKAP1 MIM:602449|HGNC:HGNC:367|Ensembl:ENSG00000121057|Vega:OTTHUMG00000140369 +8168 TW - +8170 SLC14A2 MIM:601611|HGNC:HGNC:10919|Ensembl:ENSG00000132874|Vega:OTTHUMG00000132616 +8173 CNSN MIM:212200 +8174 MADCAM1 MIM:102670|HGNC:HGNC:6765|Ensembl:ENSG00000099866|Vega:OTTHUMG00000180548 +8175 SF3A2 MIM:600796|HGNC:HGNC:10766|Ensembl:ENSG00000104897|Vega:OTTHUMG00000180414 +8177 LPSA MIM:164953 +8178 ELL MIM:600284|HGNC:HGNC:23114|Ensembl:ENSG00000105656|Vega:OTTHUMG00000183364 +8181 BFIS1 MIM:601764 +8184 HBN1 MIM:604559 +8187 ZNF239 MIM:601069|HGNC:HGNC:13031|Ensembl:ENSG00000196793|Vega:OTTHUMG00000018033 +8188 NGFG MIM:162040 +8189 SYMPK MIM:602388|HGNC:HGNC:22935|Ensembl:ENSG00000125755|Vega:OTTHUMG00000150151 +8190 MIA MIM:601340|HGNC:HGNC:7076|Ensembl:ENSG00000261857|Ensembl:ENSG00000268975|Vega:OTTHUMG00000182693|Vega:OTTHUMG00000182782 +8192 CLPP MIM:601119|HGNC:HGNC:2084|Ensembl:ENSG00000125656|Vega:OTTHUMG00000180779 +8193 DPF1 MIM:601670|HGNC:HGNC:20225|Ensembl:ENSG00000011332|Vega:OTTHUMG00000157164 +8195 MKKS MIM:604896|HGNC:HGNC:7108|Ensembl:ENSG00000125863|Vega:OTTHUMG00000031868 +8200 GDF5 MIM:601146|HGNC:HGNC:4220|Ensembl:ENSG00000125965|Vega:OTTHUMG00000032341 +8201 MLRL MIM:601308 +8202 NCOA3 MIM:601937|HGNC:HGNC:7670|Ensembl:ENSG00000124151|Vega:OTTHUMG00000033061 +8204 NRIP1 MIM:602490|HGNC:HGNC:8001|Ensembl:ENSG00000180530|Vega:OTTHUMG00000074323 +8205 TAM MIM:159595 +8208 CHAF1B MIM:601245|HGNC:HGNC:1911|Ensembl:ENSG00000159259|Vega:OTTHUMG00000086606 +8209 C21orf33 MIM:601659|HGNC:HGNC:1273|Ensembl:ENSG00000160221|Vega:OTTHUMG00000086916 +8212 AABT MIM:109660 +8213 BAS MIM:109670 +8214 DGCR6 MIM:601279|HGNC:HGNC:2846|Ensembl:ENSG00000183628|Vega:OTTHUMG00000150162 +8215 DVL1P1 MIM:601225|HGNC:HGNC:3085 +8216 LZTR1 MIM:600574|HGNC:HGNC:6742|Ensembl:ENSG00000099949|Vega:OTTHUMG00000150878 +8217 IGLJ MIM:147230 +8218 CLTCL1 MIM:601273|HGNC:HGNC:2093|Ensembl:ENSG00000070371|Vega:OTTHUMG00000150109 +8220 ESS2 MIM:601755|HGNC:HGNC:16817|Ensembl:ENSG00000100056|Vega:OTTHUMG00000150119 +8221 OGS2 MIM:145410 +8224 SYN3 MIM:602705|HGNC:HGNC:11496|Ensembl:ENSG00000185666|Vega:OTTHUMG00000031004 +8225 GTPBP6 MIM:300124|HGNC:HGNC:30189|Ensembl:ENSG00000178605|Vega:OTTHUMG00000022694 +8226 PUDP MIM:306480|HGNC:HGNC:16818|Ensembl:ENSG00000130021|Vega:OTTHUMG00000021101 +8227 AKAP17A MIM:312095|MIM:465000|HGNC:HGNC:18783|Ensembl:ENSG00000197976|Vega:OTTHUMG00000021063 +8228 PNPLA4 MIM:300102|HGNC:HGNC:24887|Ensembl:ENSG00000006757|Vega:OTTHUMG00000021103 +8231 CND MIM:304730 +8233 ZRSR2 MIM:300028|HGNC:HGNC:23019|Ensembl:ENSG00000169249|Vega:OTTHUMG00000021184 +8237 USP11 MIM:300050|HGNC:HGNC:12609|Ensembl:ENSG00000102226|Vega:OTTHUMG00000021437 +8239 USP9X MIM:300072|HGNC:HGNC:12632|Ensembl:ENSG00000124486|Vega:OTTHUMG00000021367 +8241 RBM10 MIM:300080|HGNC:HGNC:9896|Ensembl:ENSG00000182872|Vega:OTTHUMG00000021432 +8242 KDM5C MIM:314690|HGNC:HGNC:11114|Ensembl:ENSG00000126012|Vega:OTTHUMG00000021606 +8243 SMC1A MIM:300040|HGNC:HGNC:11111|Ensembl:ENSG00000072501|Vega:OTTHUMG00000021614 +8245 IDDMX MIM:300136 +8246 MRXS12 MIM:309545 +8248 DXS435E MIM:300010 +8249 MGR2 MIM:300125 +8251 HNRNPDP1 HGNC:HGNC:5038 +8255 BZX MIM:301845 +8258 GUST MIM:309555 +8259 INDX MIM:300076 +8260 NAA10 MIM:300013|HGNC:HGNC:18704|Ensembl:ENSG00000102030|Vega:OTTHUMG00000024225 +8263 F8A1 MIM:305423|HGNC:HGNC:3547|Ensembl:ENSG00000277203|Vega:OTTHUMG00000013500 +8266 UBL4A MIM:312070|HGNC:HGNC:12505|Ensembl:ENSG00000102178|Vega:OTTHUMG00000013370 +8268 IPOX MIM:300048 +8269 TMEM187 MIM:300059|HGNC:HGNC:13705|Ensembl:ENSG00000177854|Vega:OTTHUMG00000024220 +8270 LAGE3 MIM:300060|HGNC:HGNC:26058|Ensembl:ENSG00000196976|Vega:OTTHUMG00000033294 +8273 SLC10A3 MIM:312090|HGNC:HGNC:22979|Ensembl:ENSG00000126903|Vega:OTTHUMG00000013369 +8277 TKTL1 MIM:300044|HGNC:HGNC:11835|Ensembl:ENSG00000007350|Vega:OTTHUMG00000022707 +8284 KDM5D MIM:426000|HGNC:HGNC:11115|Ensembl:ENSG00000012817|Vega:OTTHUMG00000036508 +8287 USP9Y MIM:400005|HGNC:HGNC:12633|Ensembl:ENSG00000114374|Vega:OTTHUMG00000036469 +8288 EPX MIM:131399|HGNC:HGNC:3423|Ensembl:ENSG00000121053|Vega:OTTHUMG00000178802 +8289 ARID1A MIM:603024|HGNC:HGNC:11110|Ensembl:ENSG00000117713|Vega:OTTHUMG00000004004 +8290 HIST3H3 MIM:602820|HGNC:HGNC:4778|Ensembl:ENSG00000168148|Vega:OTTHUMG00000040044 +8291 DYSF MIM:603009|HGNC:HGNC:3097|Ensembl:ENSG00000135636|Vega:OTTHUMG00000129757 +8292 COLQ MIM:603033|HGNC:HGNC:2226|Ensembl:ENSG00000206561|Vega:OTTHUMG00000156233 +8293 SERF1A MIM:603011|HGNC:HGNC:10755|Ensembl:ENSG00000172058|Vega:OTTHUMG00000162419 +8294 HIST1H4I MIM:602833|HGNC:HGNC:4793|Ensembl:ENSG00000276180|Vega:OTTHUMG00000014471 +8295 TRRAP MIM:603015|HGNC:HGNC:12347|Ensembl:ENSG00000196367|Vega:OTTHUMG00000150403 +8301 PICALM MIM:603025|HGNC:HGNC:15514|Ensembl:ENSG00000073921|Vega:OTTHUMG00000166981 +8302 KLRC4 MIM:602893|HGNC:HGNC:6377|Ensembl:ENSG00000183542|Ensembl:ENSG00000255819|Vega:OTTHUMG00000168531|Vega:OTTHUMG00000168575 +8303 SNN MIM:603032|HGNC:HGNC:11149|Ensembl:ENSG00000184602|Vega:OTTHUMG00000090535 +8309 ACOX2 MIM:601641|HGNC:HGNC:120|Ensembl:ENSG00000168306|Vega:OTTHUMG00000159154 +8310 ACOX3 MIM:603402|HGNC:HGNC:121|Ensembl:ENSG00000087008|Vega:OTTHUMG00000090509 +8312 AXIN1 MIM:603816|HGNC:HGNC:903|Ensembl:ENSG00000103126|Vega:OTTHUMG00000064930 +8313 AXIN2 MIM:604025|HGNC:HGNC:904|Ensembl:ENSG00000168646|Vega:OTTHUMG00000179353 +8314 BAP1 MIM:603089|HGNC:HGNC:950|Ensembl:ENSG00000163930|Vega:OTTHUMG00000158392 +8315 BRAP MIM:604986|HGNC:HGNC:1099|Ensembl:ENSG00000089234|Vega:OTTHUMG00000169600 +8317 CDC7 MIM:603311|HGNC:HGNC:1745|Ensembl:ENSG00000097046|Vega:OTTHUMG00000047810 +8318 CDC45 MIM:603465|HGNC:HGNC:1739|Ensembl:ENSG00000093009|Vega:OTTHUMG00000150386 +8320 EOMES MIM:604615|HGNC:HGNC:3372|Ensembl:ENSG00000163508|Vega:OTTHUMG00000130570 +8321 FZD1 MIM:603408|HGNC:HGNC:4038|Ensembl:ENSG00000157240|Vega:OTTHUMG00000023046 +8322 FZD4 MIM:604579|HGNC:HGNC:4042|Ensembl:ENSG00000174804|Vega:OTTHUMG00000167231 +8323 FZD6 MIM:603409|HGNC:HGNC:4044|Ensembl:ENSG00000164930|Vega:OTTHUMG00000164840 +8324 FZD7 MIM:603410|HGNC:HGNC:4045|Ensembl:ENSG00000155760|Vega:OTTHUMG00000132841 +8325 FZD8 MIM:606146|HGNC:HGNC:4046|Ensembl:ENSG00000177283|Vega:OTTHUMG00000017956 +8326 FZD9 MIM:601766|HGNC:HGNC:4047|Ensembl:ENSG00000188763|Vega:OTTHUMG00000023051 +8327 GABPAP HGNC:HGNC:4072 +8328 GFI1B MIM:604383|HGNC:HGNC:4238|Ensembl:ENSG00000165702|Vega:OTTHUMG00000020848 +8329 HIST1H2AI MIM:602787|HGNC:HGNC:4725|Ensembl:ENSG00000196747|Vega:OTTHUMG00000014484 +8330 HIST1H2AK MIM:602788|HGNC:HGNC:4726|Ensembl:ENSG00000275221|Vega:OTTHUMG00000016382 +8331 HIST1H2AJ MIM:602791|HGNC:HGNC:4727|Ensembl:ENSG00000276368|Vega:OTTHUMG00000014486 +8332 HIST1H2AL MIM:602793|HGNC:HGNC:4730|Ensembl:ENSG00000276903|Vega:OTTHUMG00000014492 +8333 HIST1H2APS4 HGNC:HGNC:4732 +8334 HIST1H2AC MIM:602794|HGNC:HGNC:4733|Ensembl:ENSG00000180573|Vega:OTTHUMG00000014428 +8335 HIST1H2AB MIM:602795|HGNC:HGNC:4734|Ensembl:ENSG00000278463|Vega:OTTHUMG00000014420 +8336 HIST1H2AM MIM:602796|HGNC:HGNC:4735|Ensembl:ENSG00000278677|Vega:OTTHUMG00000014494 +8337 HIST2H2AA3 MIM:142720|HGNC:HGNC:4736|Ensembl:ENSG00000203812|Vega:OTTHUMG00000188678 +8338 HIST2H2AC MIM:602797|HGNC:HGNC:4738|Ensembl:ENSG00000184260|Vega:OTTHUMG00000035825 +8339 HIST1H2BG MIM:602798|HGNC:HGNC:4746|Ensembl:ENSG00000273802|Vega:OTTHUMG00000014446 +8340 HIST1H2BL MIM:602800|HGNC:HGNC:4748|Ensembl:ENSG00000185130|Vega:OTTHUMG00000014485 +8341 HIST1H2BN MIM:602801|HGNC:HGNC:4749|Ensembl:ENSG00000233822|Vega:OTTHUMG00000016397 +8342 HIST1H2BM MIM:602802|HGNC:HGNC:4750|Ensembl:ENSG00000273703|Vega:OTTHUMG00000014489 +8343 HIST1H2BF MIM:602804|HGNC:HGNC:4752|Ensembl:ENSG00000277224|Vega:OTTHUMG00000014445 +8344 HIST1H2BE MIM:602805|HGNC:HGNC:4753|Ensembl:ENSG00000274290|Vega:OTTHUMG00000014427 +8345 HIST1H2BH MIM:602806|HGNC:HGNC:4755|Ensembl:ENSG00000275713|Vega:OTTHUMG00000014447 +8346 HIST1H2BI MIM:602807|HGNC:HGNC:4756|Ensembl:ENSG00000278588|Vega:OTTHUMG00000014448 +8347 HIST1H2BC MIM:602847|HGNC:HGNC:4757|Ensembl:ENSG00000180596|Vega:OTTHUMG00000014425 +8348 HIST1H2BO MIM:602808|HGNC:HGNC:4758|Ensembl:ENSG00000274641|Vega:OTTHUMG00000014493 +8349 HIST2H2BE MIM:601831|HGNC:HGNC:4760|Ensembl:ENSG00000184678|Vega:OTTHUMG00000012095 +8350 HIST1H3A MIM:602810|HGNC:HGNC:4766|Ensembl:ENSG00000275714|Vega:OTTHUMG00000014418 +8351 HIST1H3D MIM:602811|HGNC:HGNC:4767|Ensembl:ENSG00000197409|Vega:OTTHUMG00000014433 +8352 HIST1H3C MIM:602812|HGNC:HGNC:4768|Ensembl:ENSG00000278272|Vega:OTTHUMG00000014416 +8353 HIST1H3E MIM:602813|HGNC:HGNC:4769|Ensembl:ENSG00000274750|Vega:OTTHUMG00000014434 +8354 HIST1H3I MIM:602814|HGNC:HGNC:4771|Ensembl:ENSG00000275379|Vega:OTTHUMG00000016184 +8355 HIST1H3G MIM:602815|HGNC:HGNC:4772|Ensembl:ENSG00000273983|Vega:OTTHUMG00000014436 +8356 HIST1H3J MIM:602817|HGNC:HGNC:4774|Ensembl:ENSG00000197153|Vega:OTTHUMG00000016185 +8357 HIST1H3H MIM:602818|HGNC:HGNC:4775|Ensembl:ENSG00000278828|Vega:OTTHUMG00000014483 +8358 HIST1H3B MIM:602819|HGNC:HGNC:4776|Ensembl:ENSG00000274267|Vega:OTTHUMG00000014415 +8359 HIST1H4A MIM:602822|HGNC:HGNC:4781|Ensembl:ENSG00000278637|Vega:OTTHUMG00000014419 +8360 HIST1H4D MIM:602823|HGNC:HGNC:4782|Ensembl:ENSG00000277157|Vega:OTTHUMG00000014423 +8361 HIST1H4F MIM:602824|HGNC:HGNC:4783|Ensembl:ENSG00000274618|Vega:OTTHUMG00000014443 +8362 HIST1H4K MIM:602825|HGNC:HGNC:4784|Ensembl:ENSG00000273542|Vega:OTTHUMG00000014488 +8363 HIST1H4J MIM:602826|HGNC:HGNC:4785|Ensembl:ENSG00000197238|Vega:OTTHUMG00000014487 +8364 HIST1H4C MIM:602827|HGNC:HGNC:4787|Ensembl:ENSG00000197061|Vega:OTTHUMG00000014429 +8365 HIST1H4H MIM:602828|HGNC:HGNC:4788|Ensembl:ENSG00000158406|Vega:OTTHUMG00000014454 +8366 HIST1H4B MIM:602829|HGNC:HGNC:4789|Ensembl:ENSG00000278705|Vega:OTTHUMG00000014417 +8367 HIST1H4E MIM:602830|HGNC:HGNC:4790|Ensembl:ENSG00000276966|Vega:OTTHUMG00000014441 +8368 HIST1H4L MIM:602831|HGNC:HGNC:4791|Ensembl:ENSG00000275126|Vega:OTTHUMG00000016211 +8369 HIST1H4G MIM:602832|HGNC:HGNC:4792|Ensembl:ENSG00000275663|Vega:OTTHUMG00000014444 +8370 HIST2H4A MIM:142750|HGNC:HGNC:4794|Ensembl:ENSG00000270882|Vega:OTTHUMG00000012189 +8372 HYAL3 MIM:604038|HGNC:HGNC:5322|Ensembl:ENSG00000186792|Vega:OTTHUMG00000156936 +8373 IFIT1P1 HGNC:HGNC:5408 +8377 LOH1CR1 HGNC:HGNC:6661 +8378 LOH19CR1 HGNC:HGNC:6660 +8379 MAD1L1 MIM:602686|HGNC:HGNC:6762|Ensembl:ENSG00000002822|Vega:OTTHUMG00000151493 +8382 NME5 MIM:603575|HGNC:HGNC:7853|Ensembl:ENSG00000112981|Vega:OTTHUMG00000129207 +8383 OR1A1 HGNC:HGNC:8179|Ensembl:ENSG00000172146|Vega:OTTHUMG00000090637 +8384 OR1D3P HGNC:HGNC:8184 +8386 OR1D5 HGNC:HGNC:8186|Ensembl:ENSG00000262628|Vega:OTTHUMG00000177676 +8387 OR1E1 HGNC:HGNC:8189|Ensembl:ENSG00000180016|Vega:OTTHUMG00000090643 +8388 OR1E2 HGNC:HGNC:8190|Ensembl:ENSG00000127780|Vega:OTTHUMG00000090651 +8389 OR1E3 HGNC:HGNC:8191 +8390 OR1G1 HGNC:HGNC:8204|Ensembl:ENSG00000183024|Vega:OTTHUMG00000090618 +8391 OR1P1 HGNC:HGNC:8222|Vega:OTTHUMG00000177731 +8392 OR3A3 HGNC:HGNC:8284|Ensembl:ENSG00000159961|Vega:OTTHUMG00000090649 +8394 PIP5K1A MIM:603275|HGNC:HGNC:8994|Ensembl:ENSG00000143398|Vega:OTTHUMG00000012351 +8395 PIP5K1B MIM:602745|HGNC:HGNC:8995|Ensembl:ENSG00000107242|Vega:OTTHUMG00000019976 +8396 PIP4K2B MIM:603261|HGNC:HGNC:8998|Ensembl:ENSG00000276293|Vega:OTTHUMG00000188504 +8398 PLA2G6 MIM:603604|HGNC:HGNC:9039|Ensembl:ENSG00000184381|Vega:OTTHUMG00000151246 +8399 PLA2G10 MIM:603603|HGNC:HGNC:9029|Ensembl:ENSG00000069764|Vega:OTTHUMG00000048069 +8400 SCZD6 MIM:603013|HGNC:HGNC:10654 +8401 SCZD7 MIM:603176|HGNC:HGNC:10655 +8402 SLC25A11 MIM:604165|HGNC:HGNC:10981|Ensembl:ENSG00000108528|Vega:OTTHUMG00000099395 +8403 SOX14 MIM:604747|HGNC:HGNC:11193|Ensembl:ENSG00000168875|Vega:OTTHUMG00000159757 +8404 SPARCL1 MIM:606041|HGNC:HGNC:11220|Ensembl:ENSG00000152583|Vega:OTTHUMG00000130605 +8405 SPOP MIM:602650|HGNC:HGNC:11254|Ensembl:ENSG00000121067|Vega:OTTHUMG00000161496 +8406 SRPX MIM:300187|HGNC:HGNC:11309|Ensembl:ENSG00000101955|Vega:OTTHUMG00000021362 +8407 TAGLN2 MIM:604634|HGNC:HGNC:11554|Ensembl:ENSG00000158710|Vega:OTTHUMG00000022793 +8408 ULK1 MIM:603168|HGNC:HGNC:12558|Ensembl:ENSG00000177169|Vega:OTTHUMG00000168052 +8409 UXT MIM:300234|HGNC:HGNC:12641|Ensembl:ENSG00000126756|Vega:OTTHUMG00000021453 +8410 RPS9P1 HGNC:HGNC:10443 +8411 EEA1 MIM:605070|HGNC:HGNC:3185|Ensembl:ENSG00000102189|Vega:OTTHUMG00000170110 +8412 BCAR3 MIM:604704|HGNC:HGNC:973|Ensembl:ENSG00000137936|Vega:OTTHUMG00000010301 +8416 ANXA9 MIM:603319|HGNC:HGNC:547|Ensembl:ENSG00000143412|Vega:OTTHUMG00000035063 +8417 STX7 MIM:603217|HGNC:HGNC:11442|Ensembl:ENSG00000079950|Vega:OTTHUMG00000015577 +8418 CMAHP MIM:603209|HGNC:HGNC:2098 +8419 BFSP2 MIM:603212|HGNC:HGNC:1041|Ensembl:ENSG00000170819|Vega:OTTHUMG00000159719 +8420 SNHG3 MIM:603238|HGNC:HGNC:10118|Ensembl:ENSG00000242125 +8422 MEHMO MIM:300148|HGNC:HGNC:6999 +8424 BBOX1 MIM:603312|HGNC:HGNC:964|Ensembl:ENSG00000129151|Vega:OTTHUMG00000166121 +8425 LTBP4 MIM:604710|HGNC:HGNC:6717|Ensembl:ENSG00000090006|Vega:OTTHUMG00000182635 +8427 ZNF282 MIM:603397|HGNC:HGNC:13076|Ensembl:ENSG00000170265|Vega:OTTHUMG00000158974 +8428 STK24 MIM:604984|HGNC:HGNC:11403|Ensembl:ENSG00000102572|Vega:OTTHUMG00000017250 +8431 NR0B2 MIM:604630|HGNC:HGNC:7961|Ensembl:ENSG00000131910|Vega:OTTHUMG00000004231 +8433 UTF1 MIM:604130|HGNC:HGNC:12634|Ensembl:ENSG00000171794|Vega:OTTHUMG00000019302 +8434 RECK MIM:605227|HGNC:HGNC:11345|Ensembl:ENSG00000122707|Vega:OTTHUMG00000019898 +8435 SOAT2 MIM:601311|HGNC:HGNC:11178|Ensembl:ENSG00000167780|Vega:OTTHUMG00000169774 +8436 CAVIN2 MIM:606728|HGNC:HGNC:10690|Ensembl:ENSG00000168497|Vega:OTTHUMG00000154309 +8437 RASAL1 MIM:604118|HGNC:HGNC:9873|Ensembl:ENSG00000111344|Vega:OTTHUMG00000169705 +8438 RAD54L MIM:603615|HGNC:HGNC:9826|Ensembl:ENSG00000085999|Vega:OTTHUMG00000007772 +8439 NSMAF MIM:603043|HGNC:HGNC:8017|Ensembl:ENSG00000035681|Vega:OTTHUMG00000164352 +8440 NCK2 MIM:604930|HGNC:HGNC:7665|Ensembl:ENSG00000071051|Vega:OTTHUMG00000153116 +8443 GNPAT MIM:602744|HGNC:HGNC:4416|Ensembl:ENSG00000116906|Vega:OTTHUMG00000038024 +8444 DYRK3 MIM:603497|HGNC:HGNC:3094|Ensembl:ENSG00000143479|Vega:OTTHUMG00000036339 +8445 DYRK2 MIM:603496|HGNC:HGNC:3093|Ensembl:ENSG00000127334|Vega:OTTHUMG00000169089 +8446 DUSP11 MIM:603092|HGNC:HGNC:3066|Ensembl:ENSG00000144048|Vega:OTTHUMG00000129816 +8447 DOC2B MIM:604568|HGNC:HGNC:2986|Ensembl:ENSG00000272636|Vega:OTTHUMG00000154415 +8448 DOC2A MIM:604567|HGNC:HGNC:2985|Ensembl:ENSG00000149927|Vega:OTTHUMG00000132109 +8449 DHX16 MIM:603405|HGNC:HGNC:2739|Ensembl:ENSG00000204560|Vega:OTTHUMG00000031060 +8450 CUL4B MIM:300304|HGNC:HGNC:2555|Ensembl:ENSG00000158290|Vega:OTTHUMG00000022302 +8451 CUL4A MIM:603137|HGNC:HGNC:2554|Ensembl:ENSG00000139842|Vega:OTTHUMG00000017384 +8452 CUL3 MIM:603136|HGNC:HGNC:2553|Ensembl:ENSG00000036257|Vega:OTTHUMG00000133167 +8453 CUL2 MIM:603135|HGNC:HGNC:2552|Ensembl:ENSG00000108094|Vega:OTTHUMG00000017950 +8454 CUL1 MIM:603134|HGNC:HGNC:2551|Ensembl:ENSG00000055130|Vega:OTTHUMG00000152776 +8455 ATRN MIM:603130|HGNC:HGNC:885|Ensembl:ENSG00000088812|Vega:OTTHUMG00000031746 +8456 FOXN1 MIM:600838|HGNC:HGNC:12765|Ensembl:ENSG00000109101|Vega:OTTHUMG00000132603 +8458 TTF2 MIM:604718|HGNC:HGNC:12398|Ensembl:ENSG00000116830|Vega:OTTHUMG00000012030 +8459 TPST2 MIM:603126|HGNC:HGNC:12021|Ensembl:ENSG00000128294|Vega:OTTHUMG00000150987 +8460 TPST1 MIM:603125|HGNC:HGNC:12020|Ensembl:ENSG00000169902|Vega:OTTHUMG00000023871 +8462 KLF11 MIM:603301|HGNC:HGNC:11811|Ensembl:ENSG00000172059|Vega:OTTHUMG00000119004 +8463 TEAD2 MIM:601729|HGNC:HGNC:11715|Ensembl:ENSG00000074219|Vega:OTTHUMG00000183174 +8464 SUPT3H MIM:602947|HGNC:HGNC:11466|Ensembl:ENSG00000196284|Vega:OTTHUMG00000014773 +8466 ST11 MIM:602011|HGNC:HGNC:11341 +8467 SMARCA5 MIM:603375|HGNC:HGNC:11101|Ensembl:ENSG00000153147|Vega:OTTHUMG00000161474 +8468 FKBP6 MIM:604839|HGNC:HGNC:3722|Ensembl:ENSG00000077800|Vega:OTTHUMG00000150520 +8470 SORBS2 MIM:616349|HGNC:HGNC:24098|Ensembl:ENSG00000154556|Vega:OTTHUMG00000157215 +8471 IRS4 MIM:300904|HGNC:HGNC:6128|Ensembl:ENSG00000133124|Vega:OTTHUMG00000022181 +8473 OGT MIM:300255|HGNC:HGNC:8127|Ensembl:ENSG00000147162|Vega:OTTHUMG00000033316 +8476 CDC42BPA MIM:603412|HGNC:HGNC:1737|Ensembl:ENSG00000143776|Vega:OTTHUMG00000037618 +8477 GPR65 MIM:604620|HGNC:HGNC:4517|Ensembl:ENSG00000140030|Vega:OTTHUMG00000028648 +8479 HIRIP3 MIM:603365|HGNC:HGNC:4917|Ensembl:ENSG00000149929|Vega:OTTHUMG00000132118 +8480 RAE1 MIM:603343|HGNC:HGNC:9828|Ensembl:ENSG00000101146|Vega:OTTHUMG00000032819 +8481 OFD1 MIM:300170|HGNC:HGNC:2567|Ensembl:ENSG00000046651|Vega:OTTHUMG00000021159 +8482 SEMA7A MIM:607961|HGNC:HGNC:10741|Ensembl:ENSG00000138623|Vega:OTTHUMG00000139000 +8483 CILP MIM:603489|HGNC:HGNC:1980|Ensembl:ENSG00000138615|Vega:OTTHUMG00000133140 +8484 GALR3 MIM:603692|HGNC:HGNC:4134|Ensembl:ENSG00000128310|Vega:OTTHUMG00000150658 +8487 GEMIN2 MIM:602595|HGNC:HGNC:10884|Ensembl:ENSG00000092208|Vega:OTTHUMG00000028816 +8488 RPL3P1 HGNC:HGNC:10352 +8489 RPL23AP3 HGNC:HGNC:10320 +8490 RGS5 MIM:603276|HGNC:HGNC:10001|Ensembl:ENSG00000143248|Ensembl:ENSG00000232995|Vega:OTTHUMG00000034441 +8491 MAP4K3 MIM:604921|HGNC:HGNC:6865|Ensembl:ENSG00000011566|Vega:OTTHUMG00000102127 +8492 PRSS12 MIM:606709|HGNC:HGNC:9477|Ensembl:ENSG00000164099|Vega:OTTHUMG00000161166 +8493 PPM1D MIM:605100|HGNC:HGNC:9277|Ensembl:ENSG00000170836|Vega:OTTHUMG00000180052 +8495 PPFIBP2 MIM:603142|HGNC:HGNC:9250|Ensembl:ENSG00000166387|Vega:OTTHUMG00000165617 +8496 PPFIBP1 MIM:603141|HGNC:HGNC:9249|Ensembl:ENSG00000110841|Vega:OTTHUMG00000169207 +8497 PPFIA4 MIM:603145|HGNC:HGNC:9248|Ensembl:ENSG00000143847|Vega:OTTHUMG00000042123 +8498 RANBP3 MIM:603327|HGNC:HGNC:9850|Ensembl:ENSG00000031823|Vega:OTTHUMG00000180636 +8499 PPFIA2 MIM:603143|HGNC:HGNC:9246|Ensembl:ENSG00000139220|Vega:OTTHUMG00000170181 +8500 PPFIA1 MIM:611054|HGNC:HGNC:9245|Ensembl:ENSG00000131626|Vega:OTTHUMG00000167266 +8501 SLC43A1 MIM:603733|HGNC:HGNC:9225|Ensembl:ENSG00000149150|Vega:OTTHUMG00000167030 +8502 PKP4 MIM:604276|HGNC:HGNC:9026|Ensembl:ENSG00000144283|Vega:OTTHUMG00000153969 +8503 PIK3R3 MIM:606076|HGNC:HGNC:8981|Ensembl:ENSG00000117461|Ensembl:ENSG00000278139|Vega:OTTHUMG00000008096|Vega:OTTHUMG00000186753 +8504 PEX3 MIM:603164|HGNC:HGNC:8858|Ensembl:ENSG00000034693|Vega:OTTHUMG00000015730 +8505 PARG MIM:603501|HGNC:HGNC:8605|Ensembl:ENSG00000227345|Vega:OTTHUMG00000018201 +8506 CNTNAP1 MIM:602346|HGNC:HGNC:8011|Ensembl:ENSG00000108797|Vega:OTTHUMG00000180643 +8507 ENC1 MIM:605173|HGNC:HGNC:3345|Ensembl:ENSG00000171617|Vega:OTTHUMG00000102059 +8508 NIPSNAP1 MIM:603249|HGNC:HGNC:7827|Ensembl:ENSG00000184117|Vega:OTTHUMG00000151294 +8509 NDST2 MIM:603268|HGNC:HGNC:7681|Ensembl:ENSG00000166507|Ensembl:ENSG00000272916|Vega:OTTHUMG00000018489|Vega:OTTHUMG00000185992 +8510 MMP23B MIM:603321|HGNC:HGNC:7171|Ensembl:ENSG00000189409|Vega:OTTHUMG00000074713 +8511 MMP23A MIM:603320|HGNC:HGNC:7170|Ensembl:ENSG00000215914 +8512 MBL1P HGNC:HGNC:6921|Ensembl:ENSG00000242600 +8513 LIPF MIM:601980|HGNC:HGNC:6622|Ensembl:ENSG00000182333|Vega:OTTHUMG00000018695 +8514 KCNAB2 MIM:601142|HGNC:HGNC:6229|Ensembl:ENSG00000069424|Vega:OTTHUMG00000000795 +8515 ITGA10 MIM:604042|HGNC:HGNC:6135|Ensembl:ENSG00000143127|Vega:OTTHUMG00000013751 +8516 ITGA8 MIM:604063|HGNC:HGNC:6144|Ensembl:ENSG00000077943|Vega:OTTHUMG00000017733 +8517 IKBKG MIM:300248|HGNC:HGNC:5961|Ensembl:ENSG00000269335|Vega:OTTHUMG00000024234 +8518 ELP1 MIM:603722|HGNC:HGNC:5959|Ensembl:ENSG00000070061|Vega:OTTHUMG00000020465 +8519 IFITM1 MIM:604456|HGNC:HGNC:5412|Ensembl:ENSG00000185885|Vega:OTTHUMG00000165359 +8520 HAT1 MIM:603053|HGNC:HGNC:4821|Ensembl:ENSG00000128708|Vega:OTTHUMG00000132282 +8521 GCM1 MIM:603715|HGNC:HGNC:4197|Ensembl:ENSG00000137270|Vega:OTTHUMG00000014871 +8522 GAS7 MIM:603127|HGNC:HGNC:4169|Ensembl:ENSG00000007237|Vega:OTTHUMG00000177945 +8525 DGKZ MIM:601441|HGNC:HGNC:2857|Ensembl:ENSG00000149091|Vega:OTTHUMG00000166437 +8526 DGKE MIM:601440|HGNC:HGNC:2852|Ensembl:ENSG00000153933|Vega:OTTHUMG00000178121 +8527 DGKD MIM:601826|HGNC:HGNC:2851|Ensembl:ENSG00000077044|Vega:OTTHUMG00000133290 +8528 DDO MIM:124450|HGNC:HGNC:2727|Ensembl:ENSG00000203797|Vega:OTTHUMG00000015360 +8529 CYP4F2 MIM:604426|HGNC:HGNC:2645|Ensembl:ENSG00000186115|Vega:OTTHUMG00000185995 +8530 CST7 MIM:603253|HGNC:HGNC:2479|Ensembl:ENSG00000077984|Vega:OTTHUMG00000032108 +8531 YBX3 MIM:603437|HGNC:HGNC:2428|Ensembl:ENSG00000060138|Vega:OTTHUMG00000168409 +8532 CPZ MIM:603105|HGNC:HGNC:2333|Ensembl:ENSG00000109625|Vega:OTTHUMG00000090513 +8533 COPS3 MIM:604665|HGNC:HGNC:2239|Ensembl:ENSG00000141030|Vega:OTTHUMG00000059281 +8534 CHST1 MIM:603797|HGNC:HGNC:1969|Ensembl:ENSG00000175264|Vega:OTTHUMG00000166513 +8535 CBX4 MIM:603079|HGNC:HGNC:1554|Ensembl:ENSG00000141582|Vega:OTTHUMG00000150415 +8536 CAMK1 MIM:604998|HGNC:HGNC:1459|Ensembl:ENSG00000134072|Vega:OTTHUMG00000128419 +8537 BCAS1 MIM:602968|HGNC:HGNC:974|Ensembl:ENSG00000064787|Vega:OTTHUMG00000032772 +8538 BARX2 MIM:604823|HGNC:HGNC:956|Ensembl:ENSG00000043039|Vega:OTTHUMG00000165776 +8539 API5 MIM:609774|HGNC:HGNC:594|Ensembl:ENSG00000166181|Vega:OTTHUMG00000166395 +8540 AGPS MIM:603051|HGNC:HGNC:327|Ensembl:ENSG00000018510|Vega:OTTHUMG00000132530 +8541 PPFIA3 MIM:603144|HGNC:HGNC:9247|Ensembl:ENSG00000177380|Vega:OTTHUMG00000183213 +8542 APOL1 MIM:603743|HGNC:HGNC:618|Ensembl:ENSG00000100342|Vega:OTTHUMG00000030427 +8543 LMO4 MIM:603129|HGNC:HGNC:6644|Ensembl:ENSG00000143013|Vega:OTTHUMG00000010248 +8544 PIR MIM:300931|HGNC:HGNC:30048|Ensembl:ENSG00000087842|Vega:OTTHUMG00000021176 +8545 CGGBP1 MIM:603363|HGNC:HGNC:1888|Ensembl:ENSG00000163320|Vega:OTTHUMG00000159009 +8546 AP3B1 MIM:603401|HGNC:HGNC:566|Ensembl:ENSG00000132842|Vega:OTTHUMG00000106919 +8547 FCN3 MIM:604973|HGNC:HGNC:3625|Ensembl:ENSG00000142748|Vega:OTTHUMG00000005722 +8548 BLZF1 MIM:608692|HGNC:HGNC:1065|Ensembl:ENSG00000117475|Vega:OTTHUMG00000035453 +8549 LGR5 MIM:606667|HGNC:HGNC:4504|Ensembl:ENSG00000139292|Vega:OTTHUMG00000169543 +8550 MAPKAPK5 MIM:606723|HGNC:HGNC:6889|Ensembl:ENSG00000089022|Vega:OTTHUMG00000169605 +8551 INE2 MIM:300165|HGNC:HGNC:6061|Ensembl:ENSG00000281371 +8552 INE1 MIM:300164|HGNC:HGNC:6060|Ensembl:ENSG00000224975 +8553 BHLHE40 MIM:604256|HGNC:HGNC:1046|Ensembl:ENSG00000134107|Vega:OTTHUMG00000119035 +8554 PIAS1 MIM:603566|HGNC:HGNC:2752|Ensembl:ENSG00000033800|Vega:OTTHUMG00000172645 +8555 CDC14B MIM:603505|HGNC:HGNC:1719|Ensembl:ENSG00000081377|Vega:OTTHUMG00000020300 +8556 CDC14A MIM:603504|HGNC:HGNC:1718|Ensembl:ENSG00000079335|Vega:OTTHUMG00000010987 +8557 TCAP MIM:604488|HGNC:HGNC:11610|Ensembl:ENSG00000173991|Vega:OTTHUMG00000133215 +8558 CDK10 MIM:603464|HGNC:HGNC:1770|Ensembl:ENSG00000185324|Vega:OTTHUMG00000138049 +8559 PRPF18 MIM:604993|HGNC:HGNC:17351|Ensembl:ENSG00000165630|Vega:OTTHUMG00000017702 +8560 DEGS1 MIM:615843|HGNC:HGNC:13709|Ensembl:ENSG00000143753|Vega:OTTHUMG00000037496 +8562 DENR MIM:604550|HGNC:HGNC:2769|Ensembl:ENSG00000139726|Vega:OTTHUMG00000168844 +8563 THOC5 MIM:612733|HGNC:HGNC:19074|Ensembl:ENSG00000100296|Vega:OTTHUMG00000151291 +8564 KMO MIM:603538|HGNC:HGNC:6381|Ensembl:ENSG00000117009|Vega:OTTHUMG00000039635 +8565 YARS MIM:603623|HGNC:HGNC:12840|Ensembl:ENSG00000134684|Vega:OTTHUMG00000003933 +8566 PDXK MIM:179020|HGNC:HGNC:8819|Ensembl:ENSG00000160209|Vega:OTTHUMG00000086870 +8567 MADD MIM:603584|HGNC:HGNC:6766|Ensembl:ENSG00000110514|Vega:OTTHUMG00000150350 +8568 RRP1 MIM:610653|HGNC:HGNC:18785|Ensembl:ENSG00000160214|Vega:OTTHUMG00000086884 +8569 MKNK1 MIM:606724|HGNC:HGNC:7110|Ensembl:ENSG00000079277|Vega:OTTHUMG00000007983 +8570 KHSRP MIM:603445|HGNC:HGNC:6316|Ensembl:ENSG00000088247|Vega:OTTHUMG00000180850 +8572 PDLIM4 MIM:603422|HGNC:HGNC:16501|Ensembl:ENSG00000131435|Vega:OTTHUMG00000059645 +8573 CASK MIM:300172|HGNC:HGNC:1497|Ensembl:ENSG00000147044|Vega:OTTHUMG00000021378 +8574 AKR7A2 MIM:603418|HGNC:HGNC:389|Ensembl:ENSG00000053371|Vega:OTTHUMG00000002522 +8575 PRKRA MIM:603424|HGNC:HGNC:9438|Ensembl:ENSG00000180228|Vega:OTTHUMG00000132576 +8576 STK16 MIM:604719|HGNC:HGNC:11394|Ensembl:ENSG00000115661|Vega:OTTHUMG00000154520 +8577 TMEFF1 MIM:603421|HGNC:HGNC:11866|Ensembl:ENSG00000241697|Vega:OTTHUMG00000020367 +8578 SCARF1 MIM:607873|HGNC:HGNC:16820|Ensembl:ENSG00000074660|Vega:OTTHUMG00000090555 +8580 OR8C1P HGNC:HGNC:8478 +8581 LY6D MIM:606204|HGNC:HGNC:13348|Ensembl:ENSG00000167656|Vega:OTTHUMG00000164693 +8582 OR8B1P HGNC:HGNC:8470 +8583 OR7E41P HGNC:HGNC:8415 +8585 OR7E4P HGNC:HGNC:8424 +8586 OR7E87P HGNC:HGNC:14709 +8587 OR7E2P HGNC:HGNC:8402|Ensembl:ENSG00000255203 +8588 OR7E15P HGNC:HGNC:8386 +8590 OR6A2 MIM:608495|HGNC:HGNC:15301|Ensembl:ENSG00000184933|Vega:OTTHUMG00000165736 +8591 OR5G1P HGNC:HGNC:8344 +8594 OR5D3P HGNC:HGNC:8336 +8595 OR5D2P HGNC:HGNC:8335 +8596 OR4A1P HGNC:HGNC:8289 +8600 TNFSF11 MIM:602642|HGNC:HGNC:11926|Ensembl:ENSG00000120659|Vega:OTTHUMG00000016807 +8601 RGS20 MIM:607193|HGNC:HGNC:14600|Ensembl:ENSG00000147509|Vega:OTTHUMG00000164750 +8602 NOP14 MIM:611526|HGNC:HGNC:16821|Ensembl:ENSG00000087269|Vega:OTTHUMG00000159911 +8603 FAM193A HGNC:HGNC:16822|Ensembl:ENSG00000125386|Vega:OTTHUMG00000160512 +8604 SLC25A12 MIM:603667|HGNC:HGNC:10982|Ensembl:ENSG00000115840|Vega:OTTHUMG00000134290 +8605 PLA2G4C MIM:603602|HGNC:HGNC:9037|Ensembl:ENSG00000105499|Vega:OTTHUMG00000183185 +8607 RUVBL1 MIM:603449|HGNC:HGNC:10474|Ensembl:ENSG00000175792|Vega:OTTHUMG00000159658 +8608 RDH16 HGNC:HGNC:29674|Ensembl:ENSG00000139547|Vega:OTTHUMG00000170895 +8609 KLF7 MIM:604865|HGNC:HGNC:6350|Ensembl:ENSG00000118263|Vega:OTTHUMG00000132935 +8611 PLPP1 MIM:607124|HGNC:HGNC:9228|Ensembl:ENSG00000067113|Vega:OTTHUMG00000162240 +8612 PLPP2 MIM:607126|HGNC:HGNC:9230|Ensembl:ENSG00000141934|Vega:OTTHUMG00000180530 +8613 PLPP3 MIM:607125|HGNC:HGNC:9229|Ensembl:ENSG00000162407|Vega:OTTHUMG00000008160 +8614 STC2 MIM:603665|HGNC:HGNC:11374|Ensembl:ENSG00000113739|Vega:OTTHUMG00000130542 +8615 USO1 MIM:603344|HGNC:HGNC:30904|Ensembl:ENSG00000138768|Vega:OTTHUMG00000160952 +8618 CADPS MIM:604667|HGNC:HGNC:1426|Ensembl:ENSG00000163618|Vega:OTTHUMG00000158651 +8620 NPFF MIM:604643|HGNC:HGNC:7901|Ensembl:ENSG00000139574|Vega:OTTHUMG00000169856 +8621 CDK13 MIM:603309|HGNC:HGNC:1733|Ensembl:ENSG00000065883|Vega:OTTHUMG00000023726 +8622 PDE8B MIM:603390|HGNC:HGNC:8794|Ensembl:ENSG00000113231|Vega:OTTHUMG00000102170 +8623 ASMTL MIM:300162|MIM:400011|HGNC:HGNC:751|Ensembl:ENSG00000169093|Vega:OTTHUMG00000021057 +8624 PSMG1 MIM:605296|HGNC:HGNC:3043|Ensembl:ENSG00000183527|Vega:OTTHUMG00000066034 +8625 RFXANK MIM:603200|HGNC:HGNC:9987|Ensembl:ENSG00000064490|Vega:OTTHUMG00000169224 +8626 TP63 MIM:603273|HGNC:HGNC:15979|Ensembl:ENSG00000073282|Vega:OTTHUMG00000156313 +8629 JRK MIM:603210|HGNC:HGNC:6199|Ensembl:ENSG00000234616|Vega:OTTHUMG00000160911 +8630 HSD17B6 MIM:606623|HGNC:HGNC:23316|Ensembl:ENSG00000025423|Vega:OTTHUMG00000170854 +8631 SKAP1 MIM:604969|HGNC:HGNC:15605|Ensembl:ENSG00000141293|Vega:OTTHUMG00000178823 +8632 DNAH17 MIM:610063|HGNC:HGNC:2946|Ensembl:ENSG00000187775|Vega:OTTHUMG00000150216 +8633 UNC5C MIM:603610|HGNC:HGNC:12569|Ensembl:ENSG00000182168|Vega:OTTHUMG00000130989 +8634 RTCA MIM:611286|HGNC:HGNC:17981|Ensembl:ENSG00000137996|Vega:OTTHUMG00000010920 +8635 RNASET2 MIM:612944|HGNC:HGNC:21686|Ensembl:ENSG00000026297|Vega:OTTHUMG00000016009 +8636 SSNA1 MIM:610882|HGNC:HGNC:11321|Ensembl:ENSG00000176101|Vega:OTTHUMG00000020982 +8637 EIF4EBP3 MIM:603483|HGNC:HGNC:3290|Ensembl:ENSG00000243056|Vega:OTTHUMG00000129498 +8638 OASL MIM:603281|HGNC:HGNC:8090|Ensembl:ENSG00000135114|Vega:OTTHUMG00000154981 +8639 AOC3 MIM:603735|HGNC:HGNC:550|Ensembl:ENSG00000131471|Vega:OTTHUMG00000180656 +8641 PCDHGB4 MIM:603058|HGNC:HGNC:8711|Ensembl:ENSG00000253953|Vega:OTTHUMG00000163686 +8642 DCHS1 MIM:603057|HGNC:HGNC:13681|Ensembl:ENSG00000166341|Vega:OTTHUMG00000133398 +8643 PTCH2 MIM:603673|HGNC:HGNC:9586|Ensembl:ENSG00000117425|Vega:OTTHUMG00000008490 +8644 AKR1C3 MIM:603966|HGNC:HGNC:386|Ensembl:ENSG00000196139|Vega:OTTHUMG00000017585 +8645 KCNK5 MIM:603493|HGNC:HGNC:6280|Ensembl:ENSG00000164626|Vega:OTTHUMG00000014642 +8646 CHRD MIM:603475|HGNC:HGNC:1949|Ensembl:ENSG00000090539|Vega:OTTHUMG00000141267 +8647 ABCB11 MIM:603201|HGNC:HGNC:42|Ensembl:ENSG00000073734|Vega:OTTHUMG00000154039 +8648 NCOA1 MIM:602691|HGNC:HGNC:7668|Ensembl:ENSG00000084676|Vega:OTTHUMG00000125523 +8649 LAMTOR3 MIM:603296|HGNC:HGNC:15606|Ensembl:ENSG00000109270|Vega:OTTHUMG00000131050 +8650 NUMB MIM:603728|HGNC:HGNC:8060|Ensembl:ENSG00000133961|Vega:OTTHUMG00000171436 +8651 SOCS1 MIM:603597|HGNC:HGNC:19383|Ensembl:ENSG00000185338|Vega:OTTHUMG00000129792 +8653 DDX3Y MIM:400010|HGNC:HGNC:2699|Ensembl:ENSG00000067048|Vega:OTTHUMG00000036324 +8654 PDE5A MIM:603310|HGNC:HGNC:8784|Ensembl:ENSG00000138735|Vega:OTTHUMG00000132971 +8655 DYNLL1 MIM:601562|HGNC:HGNC:15476|Ensembl:ENSG00000088986|Vega:OTTHUMG00000169368 +8658 TNKS MIM:603303|HGNC:HGNC:11941|Ensembl:ENSG00000173273|Vega:OTTHUMG00000090481 +8659 ALDH4A1 MIM:606811|HGNC:HGNC:406|Ensembl:ENSG00000159423|Vega:OTTHUMG00000002443 +8660 IRS2 MIM:600797|HGNC:HGNC:6126|Ensembl:ENSG00000185950|Vega:OTTHUMG00000017338 +8661 EIF3A MIM:602039|HGNC:HGNC:3271|Ensembl:ENSG00000107581|Vega:OTTHUMG00000019144 +8662 EIF3B MIM:603917|HGNC:HGNC:3280|Ensembl:ENSG00000106263|Vega:OTTHUMG00000022839 +8663 EIF3C MIM:603916|HGNC:HGNC:3279|Ensembl:ENSG00000184110|Vega:OTTHUMG00000099443 +8664 EIF3D MIM:603915|HGNC:HGNC:3278|Ensembl:ENSG00000100353|Vega:OTTHUMG00000150599 +8665 EIF3F MIM:603914|HGNC:HGNC:3275|Ensembl:ENSG00000175390|Vega:OTTHUMG00000165675 +8666 EIF3G MIM:603913|HGNC:HGNC:3274|Ensembl:ENSG00000130811|Vega:OTTHUMG00000180396 +8667 EIF3H MIM:603912|HGNC:HGNC:3273|Ensembl:ENSG00000147677|Vega:OTTHUMG00000164919 +8668 EIF3I MIM:603911|HGNC:HGNC:3272|Ensembl:ENSG00000084623|Vega:OTTHUMG00000007364 +8669 EIF3J MIM:603910|HGNC:HGNC:3270|Ensembl:ENSG00000104131|Vega:OTTHUMG00000131158 +8671 SLC4A4 MIM:603345|HGNC:HGNC:11030|Ensembl:ENSG00000080493|Vega:OTTHUMG00000129907 +8672 EIF4G3 MIM:603929|HGNC:HGNC:3298|Ensembl:ENSG00000075151|Vega:OTTHUMG00000002624 +8673 VAMP8 MIM:603177|HGNC:HGNC:12647|Ensembl:ENSG00000118640|Vega:OTTHUMG00000130180 +8674 VAMP4 MIM:606909|HGNC:HGNC:12645|Ensembl:ENSG00000117533|Vega:OTTHUMG00000034788 +8675 STX16 MIM:603666|HGNC:HGNC:11431|Ensembl:ENSG00000124222|Vega:OTTHUMG00000033084 +8676 STX11 MIM:605014|HGNC:HGNC:11429|Ensembl:ENSG00000135604|Vega:OTTHUMG00000015739 +8677 STX10 MIM:603765|HGNC:HGNC:11428|Ensembl:ENSG00000104915|Vega:OTTHUMG00000180759 +8678 BECN1 MIM:604378|HGNC:HGNC:1034|Ensembl:ENSG00000126581|Vega:OTTHUMG00000180653 +8681 JMJD7-PLA2G4B HGNC:HGNC:34449|Ensembl:ENSG00000168970|Vega:OTTHUMG00000044442 +8682 PEA15 MIM:603434|HGNC:HGNC:8822|Ensembl:ENSG00000162734|Vega:OTTHUMG00000031605 +8683 SRSF9 MIM:601943|HGNC:HGNC:10791|Ensembl:ENSG00000111786|Vega:OTTHUMG00000047790 +8685 MARCO MIM:604870|HGNC:HGNC:6895|Ensembl:ENSG00000019169|Vega:OTTHUMG00000131400 +8686 KRT41P HGNC:HGNC:6457 +8687 KRT38 MIM:604542|HGNC:HGNC:6456|Ensembl:ENSG00000171360|Vega:OTTHUMG00000133439 +8688 KRT37 MIM:604541|HGNC:HGNC:6455|Ensembl:ENSG00000108417|Vega:OTTHUMG00000133606 +8689 KRT36 MIM:604540|HGNC:HGNC:6454|Ensembl:ENSG00000126337|Vega:OTTHUMG00000133431 +8690 JRKL MIM:603211|HGNC:HGNC:6200|Ensembl:ENSG00000183340|Vega:OTTHUMG00000154950 +8691 IDDM17 MIM:603266|HGNC:HGNC:5371 +8692 HYAL2 MIM:603551|HGNC:HGNC:5321|Ensembl:ENSG00000068001|Vega:OTTHUMG00000156876 +8693 GALNT4 MIM:603565|HGNC:HGNC:4126|Ensembl:ENSG00000257594|Vega:OTTHUMG00000166292 +8694 DGAT1 MIM:604900|HGNC:HGNC:2843|Ensembl:ENSG00000185000|Vega:OTTHUMG00000174606 +8697 CDC23 MIM:603462|HGNC:HGNC:1724|Ensembl:ENSG00000094880|Vega:OTTHUMG00000129198 +8698 S1PR4 MIM:603751|HGNC:HGNC:3170|Ensembl:ENSG00000125910|Vega:OTTHUMG00000180672 +8701 DNAH11 MIM:603339|HGNC:HGNC:2942|Ensembl:ENSG00000105877|Vega:OTTHUMG00000152524 +8702 B4GALT4 MIM:604015|HGNC:HGNC:927|Ensembl:ENSG00000121578|Vega:OTTHUMG00000159358 +8703 B4GALT3 MIM:604014|HGNC:HGNC:926|Ensembl:ENSG00000158850|Vega:OTTHUMG00000034348 +8704 B4GALT2 MIM:604013|HGNC:HGNC:925|Ensembl:ENSG00000117411|Vega:OTTHUMG00000008296 +8705 B3GALT4 MIM:603095|HGNC:HGNC:919|Ensembl:ENSG00000235863|Vega:OTTHUMG00000031100 +8706 B3GALNT1 MIM:603094|HGNC:HGNC:918|Ensembl:ENSG00000169255|Vega:OTTHUMG00000159064 +8707 B3GALT2 MIM:603018|HGNC:HGNC:917|Ensembl:ENSG00000162630|Vega:OTTHUMG00000035687 +8708 B3GALT1 MIM:603093|HGNC:HGNC:916|Ensembl:ENSG00000172318|Vega:OTTHUMG00000132163 +8710 SERPINB7 MIM:603357|HGNC:HGNC:13902|Ensembl:ENSG00000166396|Vega:OTTHUMG00000060591 +8711 TNK1 MIM:608076|HGNC:HGNC:11940|Ensembl:ENSG00000174292|Vega:OTTHUMG00000178174 +8712 PAGE1 MIM:300288|HGNC:HGNC:4107|Ensembl:ENSG00000068985|Vega:OTTHUMG00000033224 +8714 ABCC3 MIM:604323|HGNC:HGNC:54|Ensembl:ENSG00000108846|Vega:OTTHUMG00000162245 +8715 NOL4 MIM:603577|HGNC:HGNC:7870|Ensembl:ENSG00000101746|Vega:OTTHUMG00000132291 +8717 TRADD MIM:603500|HGNC:HGNC:12030|Ensembl:ENSG00000102871|Vega:OTTHUMG00000137519 +8718 TNFRSF25 MIM:603366|HGNC:HGNC:11910|Ensembl:ENSG00000215788|Vega:OTTHUMG00000000831 +8720 MBTPS1 MIM:603355|HGNC:HGNC:15456|Ensembl:ENSG00000140943|Vega:OTTHUMG00000137639 +8721 EDF1 MIM:605107|HGNC:HGNC:3164|Ensembl:ENSG00000107223|Vega:OTTHUMG00000020948 +8722 CTSF MIM:603539|HGNC:HGNC:2531|Ensembl:ENSG00000174080|Vega:OTTHUMG00000167090 +8723 SNX4 MIM:605931|HGNC:HGNC:11175|Ensembl:ENSG00000114520|Vega:OTTHUMG00000159575 +8724 SNX3 MIM:605930|HGNC:HGNC:11174|Ensembl:ENSG00000112335|Vega:OTTHUMG00000015323 +8725 URI1 MIM:603494|HGNC:HGNC:13236|Ensembl:ENSG00000105176|Vega:OTTHUMG00000177923 +8726 EED MIM:605984|HGNC:HGNC:3188|Ensembl:ENSG00000074266|Vega:OTTHUMG00000167209 +8727 CTNNAL1 MIM:604785|HGNC:HGNC:2512|Ensembl:ENSG00000119326|Vega:OTTHUMG00000020466 +8728 ADAM19 MIM:603640|HGNC:HGNC:197|Ensembl:ENSG00000135074|Vega:OTTHUMG00000130242 +8729 GBF1 MIM:603698|HGNC:HGNC:4181|Ensembl:ENSG00000107862|Vega:OTTHUMG00000018955 +8731 RNMT MIM:603514|HGNC:HGNC:10075|Ensembl:ENSG00000101654|Vega:OTTHUMG00000131718 +8732 RNGTT MIM:603512|HGNC:HGNC:10073|Ensembl:ENSG00000111880|Vega:OTTHUMG00000015190 +8733 GPAA1 MIM:603048|HGNC:HGNC:4446|Ensembl:ENSG00000197858|Vega:OTTHUMG00000165438 +8735 MYH13 MIM:603487|HGNC:HGNC:7571|Ensembl:ENSG00000006788|Vega:OTTHUMG00000177987 +8736 MYOM1 MIM:603508|HGNC:HGNC:7613|Ensembl:ENSG00000101605|Vega:OTTHUMG00000178209 +8737 RIPK1 MIM:603453|HGNC:HGNC:10019|Ensembl:ENSG00000137275|Vega:OTTHUMG00000014134 +8738 CRADD MIM:603454|HGNC:HGNC:2340|Ensembl:ENSG00000169372|Vega:OTTHUMG00000170322 +8739 HRK MIM:603447|HGNC:HGNC:5185|Ensembl:ENSG00000135116|Vega:OTTHUMG00000169328 +8740 TNFSF14 MIM:604520|HGNC:HGNC:11930|Ensembl:ENSG00000125735|Vega:OTTHUMG00000181835 +8741 TNFSF13 MIM:604472|HGNC:HGNC:11928|Ensembl:ENSG00000161955|Vega:OTTHUMG00000108145 +8742 TNFSF12 MIM:602695|HGNC:HGNC:11927|Ensembl:ENSG00000239697|Vega:OTTHUMG00000108148 +8743 TNFSF10 MIM:603598|HGNC:HGNC:11925|Ensembl:ENSG00000121858|Vega:OTTHUMG00000156917 +8744 TNFSF9 MIM:606182|HGNC:HGNC:11939|Ensembl:ENSG00000125657|Vega:OTTHUMG00000181831 +8745 ADAM23 MIM:603710|HGNC:HGNC:202|Ensembl:ENSG00000114948|Vega:OTTHUMG00000132919 +8747 ADAM21 MIM:603713|HGNC:HGNC:200|Ensembl:ENSG00000139985|Vega:OTTHUMG00000171328 +8748 ADAM20 MIM:603712|HGNC:HGNC:199|Ensembl:ENSG00000134007|Vega:OTTHUMG00000167548 +8749 ADAM18 HGNC:HGNC:196|Ensembl:ENSG00000168619|Vega:OTTHUMG00000164040 +8751 ADAM15 MIM:605548|HGNC:HGNC:193|Ensembl:ENSG00000143537|Vega:OTTHUMG00000013898 +8754 ADAM9 MIM:602713|HGNC:HGNC:216|Ensembl:ENSG00000168615|Vega:OTTHUMG00000159783 +8755 ADAM6 HGNC:HGNC:213|Ensembl:ENSG00000271968 +8756 ADAM7 MIM:607310|HGNC:HGNC:214|Ensembl:ENSG00000069206|Vega:OTTHUMG00000097859 +8759 ADAM1A HGNC:HGNC:187 +8760 CDS2 MIM:603549|HGNC:HGNC:1801|Ensembl:ENSG00000101290|Vega:OTTHUMG00000031801 +8761 PABPC4 MIM:603407|HGNC:HGNC:8557|Ensembl:ENSG00000090621|Vega:OTTHUMG00000009097 +8763 CD164 MIM:603356|HGNC:HGNC:1632|Ensembl:ENSG00000135535|Vega:OTTHUMG00000015339 +8764 TNFRSF14 MIM:602746|HGNC:HGNC:11912|Ensembl:ENSG00000157873|Vega:OTTHUMG00000000792 +8766 RAB11A MIM:605570|HGNC:HGNC:9760|Ensembl:ENSG00000103769|Vega:OTTHUMG00000133162 +8767 RIPK2 MIM:603455|HGNC:HGNC:10020|Ensembl:ENSG00000104312|Vega:OTTHUMG00000163809 +8771 TNFRSF6B MIM:603361|HGNC:HGNC:11921|Ensembl:ENSG00000243509|Vega:OTTHUMG00000143724 +8772 FADD MIM:602457|HGNC:HGNC:3573|Ensembl:ENSG00000168040|Vega:OTTHUMG00000167264 +8773 SNAP23 MIM:602534|HGNC:HGNC:11131|Ensembl:ENSG00000092531|Vega:OTTHUMG00000130625 +8774 NAPG MIM:603216|HGNC:HGNC:7642|Ensembl:ENSG00000134265|Vega:OTTHUMG00000179119 +8775 NAPA MIM:603215|HGNC:HGNC:7641|Ensembl:ENSG00000105402|Vega:OTTHUMG00000183294 +8776 MTMR1 MIM:300171|HGNC:HGNC:7449|Ensembl:ENSG00000063601|Vega:OTTHUMG00000024159 +8777 MPDZ MIM:603785|HGNC:HGNC:7208|Ensembl:ENSG00000107186|Vega:OTTHUMG00000021031 +8778 SIGLEC5 MIM:604200|HGNC:HGNC:10874|Ensembl:ENSG00000105501|Ensembl:ENSG00000268500|Vega:OTTHUMG00000165510|Vega:OTTHUMG00000188645 +8780 RIOK3 MIM:603579|HGNC:HGNC:11451|Ensembl:ENSG00000101782|Vega:OTTHUMG00000131813 +8781 PSPHP1 MIM:604239|HGNC:HGNC:9578 +8782 MYP3 MIM:603221|HGNC:HGNC:7617 +8784 TNFRSF18 MIM:603905|HGNC:HGNC:11914|Ensembl:ENSG00000186891|Vega:OTTHUMG00000001414 +8785 MATN4 MIM:603897|HGNC:HGNC:6910|Ensembl:ENSG00000124159|Vega:OTTHUMG00000033043 +8786 RGS11 MIM:603895|HGNC:HGNC:9993|Ensembl:ENSG00000076344|Vega:OTTHUMG00000064893 +8787 RGS9 MIM:604067|HGNC:HGNC:10004|Ensembl:ENSG00000108370|Vega:OTTHUMG00000179349 +8788 DLK1 MIM:176290|HGNC:HGNC:2907|Ensembl:ENSG00000185559|Vega:OTTHUMG00000171600 +8789 FBP2 MIM:603027|HGNC:HGNC:3607|Ensembl:ENSG00000130957|Vega:OTTHUMG00000020269 +8790 FPGT MIM:603609|HGNC:HGNC:3825|Ensembl:ENSG00000254685|Vega:OTTHUMG00000009571 +8792 TNFRSF11A MIM:603499|HGNC:HGNC:11908|Ensembl:ENSG00000141655|Vega:OTTHUMG00000132779 +8793 TNFRSF10D MIM:603614|HGNC:HGNC:11907|Ensembl:ENSG00000173530|Vega:OTTHUMG00000097845 +8794 TNFRSF10C MIM:603613|HGNC:HGNC:11906|Ensembl:ENSG00000173535|Vega:OTTHUMG00000097844 +8795 TNFRSF10B MIM:603612|HGNC:HGNC:11905|Ensembl:ENSG00000120889|Vega:OTTHUMG00000097826 +8796 SCEL MIM:604112|HGNC:HGNC:10573|Ensembl:ENSG00000136155|Vega:OTTHUMG00000017107 +8797 TNFRSF10A MIM:603611|HGNC:HGNC:11904|Ensembl:ENSG00000104689|Vega:OTTHUMG00000097843 +8798 DYRK4 MIM:609181|HGNC:HGNC:3095|Ensembl:ENSG00000010219|Vega:OTTHUMG00000168204 +8799 PEX11B MIM:603867|HGNC:HGNC:8853|Ensembl:ENSG00000131779|Vega:OTTHUMG00000013756 +8800 PEX11A MIM:603866|HGNC:HGNC:8852|Ensembl:ENSG00000166821|Vega:OTTHUMG00000149809 +8801 SUCLG2 MIM:603922|HGNC:HGNC:11450|Ensembl:ENSG00000172340|Vega:OTTHUMG00000158740 +8802 SUCLG1 MIM:611224|HGNC:HGNC:11449|Ensembl:ENSG00000163541|Vega:OTTHUMG00000130023 +8803 SUCLA2 MIM:603921|HGNC:HGNC:11448|Ensembl:ENSG00000136143|Vega:OTTHUMG00000016889 +8804 CREG1 HGNC:HGNC:2351|Ensembl:ENSG00000143162|Vega:OTTHUMG00000034682 +8805 TRIM24 MIM:603406|HGNC:HGNC:11812|Ensembl:ENSG00000122779|Vega:OTTHUMG00000155820 +8806 SCZD8 MIM:603206|HGNC:HGNC:10656 +8807 IL18RAP MIM:604509|HGNC:HGNC:5989|Ensembl:ENSG00000115607|Vega:OTTHUMG00000130777 +8808 IL1RL2 MIM:604512|HGNC:HGNC:5999|Ensembl:ENSG00000115598|Vega:OTTHUMG00000130776 +8809 IL18R1 MIM:604494|HGNC:HGNC:5988|Ensembl:ENSG00000115604|Vega:OTTHUMG00000130780 +8811 GALR2 MIM:603691|HGNC:HGNC:4133|Ensembl:ENSG00000182687|Vega:OTTHUMG00000167479 +8812 CCNK MIM:603544|HGNC:HGNC:1596|Ensembl:ENSG00000090061|Vega:OTTHUMG00000171495 +8813 DPM1 MIM:603503|HGNC:HGNC:3005|Ensembl:ENSG00000000419|Vega:OTTHUMG00000032742 +8814 CDKL1 MIM:603441|HGNC:HGNC:1781|Ensembl:ENSG00000100490|Vega:OTTHUMG00000140290 +8815 BANF1 MIM:603811|HGNC:HGNC:17397|Ensembl:ENSG00000175334|Vega:OTTHUMG00000166749 +8816 DCAF5 MIM:603812|HGNC:HGNC:20224|Ensembl:ENSG00000139990|Vega:OTTHUMG00000171699 +8817 FGF18 MIM:603726|HGNC:HGNC:3674|Ensembl:ENSG00000156427|Vega:OTTHUMG00000130464 +8818 DPM2 MIM:603564|HGNC:HGNC:3006|Ensembl:ENSG00000136908|Vega:OTTHUMG00000020725 +8819 SAP30 MIM:603378|HGNC:HGNC:10532|Ensembl:ENSG00000164105|Vega:OTTHUMG00000160798 +8820 HESX1 MIM:601802|HGNC:HGNC:4877|Ensembl:ENSG00000163666|Vega:OTTHUMG00000158597 +8821 INPP4B MIM:607494|HGNC:HGNC:6075|Ensembl:ENSG00000109452|Vega:OTTHUMG00000161341 +8822 FGF17 MIM:603725|HGNC:HGNC:3673|Ensembl:ENSG00000158815|Vega:OTTHUMG00000097051 +8823 FGF16 MIM:300827|MIM:309630|HGNC:HGNC:3672|Ensembl:ENSG00000196468|Vega:OTTHUMG00000013133 +8824 CES2 MIM:605278|HGNC:HGNC:1864|Ensembl:ENSG00000172831|Vega:OTTHUMG00000137517 +8825 LIN7A MIM:603380|HGNC:HGNC:17787|Ensembl:ENSG00000111052|Vega:OTTHUMG00000170168 +8826 IQGAP1 MIM:603379|HGNC:HGNC:6110|Ensembl:ENSG00000140575|Vega:OTTHUMG00000149832 +8828 NRP2 MIM:602070|HGNC:HGNC:8005|Ensembl:ENSG00000118257|Vega:OTTHUMG00000132893 +8829 NRP1 MIM:602069|HGNC:HGNC:8004|Ensembl:ENSG00000099250|Vega:OTTHUMG00000019343 +8830 PTLAH MIM:168860|HGNC:HGNC:9622 +8831 SYNGAP1 MIM:603384|HGNC:HGNC:11497|Ensembl:ENSG00000197283|Vega:OTTHUMG00000031096 +8832 CD84 MIM:604513|HGNC:HGNC:1704|Ensembl:ENSG00000066294|Vega:OTTHUMG00000022788 +8833 GMPS MIM:600358|HGNC:HGNC:4378|Ensembl:ENSG00000163655|Vega:OTTHUMG00000158551 +8834 TMEM11 HGNC:HGNC:16823|Ensembl:ENSG00000178307|Vega:OTTHUMG00000178971 +8835 SOCS2 MIM:605117|HGNC:HGNC:19382|Ensembl:ENSG00000120833|Vega:OTTHUMG00000170160 +8836 GGH MIM:601509|HGNC:HGNC:4248|Ensembl:ENSG00000137563|Vega:OTTHUMG00000164365 +8837 CFLAR MIM:603599|HGNC:HGNC:1876|Ensembl:ENSG00000003402|Vega:OTTHUMG00000132819 +8838 WISP3 MIM:603400|HGNC:HGNC:12771|Ensembl:ENSG00000112761|Vega:OTTHUMG00000185101 +8839 WISP2 MIM:603399|HGNC:HGNC:12770|Ensembl:ENSG00000064205|Vega:OTTHUMG00000033071 +8840 WISP1 MIM:603398|HGNC:HGNC:12769|Ensembl:ENSG00000104415|Vega:OTTHUMG00000164440 +8841 HDAC3 MIM:605166|HGNC:HGNC:4854|Ensembl:ENSG00000171720|Vega:OTTHUMG00000129629 +8842 PROM1 MIM:604365|HGNC:HGNC:9454|Ensembl:ENSG00000007062|Vega:OTTHUMG00000160180 +8843 HCAR3 MIM:606039|HGNC:HGNC:16824|Ensembl:ENSG00000255398|Vega:OTTHUMG00000166034 +8844 KSR1 MIM:601132|HGNC:HGNC:6465|Ensembl:ENSG00000141068|Vega:OTTHUMG00000132051 +8846 ALKBH1 MIM:605345|HGNC:HGNC:17911|Ensembl:ENSG00000100601|Vega:OTTHUMG00000171542 +8847 DLEU2 MIM:605766|HGNC:HGNC:13748|Ensembl:ENSG00000231607 +8848 TSC22D1 MIM:607715|HGNC:HGNC:16826|Ensembl:ENSG00000102804|Vega:OTTHUMG00000016838 +8850 KAT2B MIM:602303|HGNC:HGNC:8638|Ensembl:ENSG00000114166|Vega:OTTHUMG00000130481 +8851 CDK5R1 MIM:603460|HGNC:HGNC:1775|Ensembl:ENSG00000176749|Vega:OTTHUMG00000132814 +8852 AKAP4 MIM:300185|HGNC:HGNC:374|Ensembl:ENSG00000147081|Vega:OTTHUMG00000021517 +8853 ASAP2 MIM:603817|HGNC:HGNC:2721|Ensembl:ENSG00000151693|Vega:OTTHUMG00000117485 +8854 ALDH1A2 MIM:603687|HGNC:HGNC:15472|Ensembl:ENSG00000128918|Vega:OTTHUMG00000132624 +8856 NR1I2 MIM:603065|HGNC:HGNC:7968|Ensembl:ENSG00000144852|Vega:OTTHUMG00000159400 +8857 FCGBP MIM:617553|HGNC:HGNC:13572|Ensembl:ENSG00000275395|Vega:OTTHUMG00000182580 +8858 PROZ MIM:176895|HGNC:HGNC:9460|Ensembl:ENSG00000126231|Vega:OTTHUMG00000017376 +8859 STK19 MIM:604977|HGNC:HGNC:11398|Ensembl:ENSG00000204344|Vega:OTTHUMG00000166424 +8861 LDB1 MIM:603451|HGNC:HGNC:6532|Ensembl:ENSG00000198728|Vega:OTTHUMG00000018950 +8862 APLN MIM:300297|HGNC:HGNC:16665|Ensembl:ENSG00000171388|Vega:OTTHUMG00000022371 +8863 PER3 MIM:603427|HGNC:HGNC:8847|Ensembl:ENSG00000049246|Vega:OTTHUMG00000001216 +8864 PER2 MIM:603426|HGNC:HGNC:8846|Ensembl:ENSG00000132326|Vega:OTTHUMG00000152884 +8867 SYNJ1 MIM:604297|HGNC:HGNC:11503|Ensembl:ENSG00000159082|Vega:OTTHUMG00000064926 +8869 ST3GAL5 MIM:604402|HGNC:HGNC:10872|Ensembl:ENSG00000115525|Vega:OTTHUMG00000130171 +8870 IER3 MIM:602996|HGNC:HGNC:5392|Ensembl:ENSG00000137331|Vega:OTTHUMG00000031265 +8871 SYNJ2 MIM:609410|HGNC:HGNC:11504|Ensembl:ENSG00000078269|Vega:OTTHUMG00000015904 +8872 CDC123 HGNC:HGNC:16827|Ensembl:ENSG00000151465|Vega:OTTHUMG00000017680 +8874 ARHGEF7 MIM:605477|HGNC:HGNC:15607|Ensembl:ENSG00000102606|Vega:OTTHUMG00000017357 +8875 VNN2 MIM:603571|HGNC:HGNC:12706|Ensembl:ENSG00000112303|Vega:OTTHUMG00000015588 +8876 VNN1 MIM:603570|HGNC:HGNC:12705|Ensembl:ENSG00000112299|Vega:OTTHUMG00000015587 +8877 SPHK1 MIM:603730|HGNC:HGNC:11240|Ensembl:ENSG00000176170|Vega:OTTHUMG00000180177 +8878 SQSTM1 MIM:601530|HGNC:HGNC:11280|Ensembl:ENSG00000161011|Vega:OTTHUMG00000150643 +8879 SGPL1 MIM:603729|HGNC:HGNC:10817|Ensembl:ENSG00000166224|Vega:OTTHUMG00000018421 +8880 FUBP1 MIM:603444|HGNC:HGNC:4004|Ensembl:ENSG00000162613|Vega:OTTHUMG00000040799 +8881 CDC16 MIM:603461|HGNC:HGNC:1720|Ensembl:ENSG00000130177|Vega:OTTHUMG00000017402 +8882 ZPR1 MIM:603901|HGNC:HGNC:13051|Ensembl:ENSG00000109917|Vega:OTTHUMG00000046114 +8883 NAE1 MIM:603385|HGNC:HGNC:621|Ensembl:ENSG00000159593|Vega:OTTHUMG00000137513 +8884 SLC5A6 MIM:604024|HGNC:HGNC:11041|Ensembl:ENSG00000138074|Vega:OTTHUMG00000097075 +8886 DDX18 MIM:606355|HGNC:HGNC:2741|Ensembl:ENSG00000088205|Vega:OTTHUMG00000058521 +8887 TAX1BP1 MIM:605326|HGNC:HGNC:11575|Ensembl:ENSG00000106052|Vega:OTTHUMG00000023377 +8888 MCM3AP MIM:603294|HGNC:HGNC:6946|Ensembl:ENSG00000160294|Vega:OTTHUMG00000090630 +8890 EIF2B4 MIM:606687|HGNC:HGNC:3260|Ensembl:ENSG00000115211|Vega:OTTHUMG00000151927 +8891 EIF2B3 MIM:606273|HGNC:HGNC:3259|Ensembl:ENSG00000070785|Vega:OTTHUMG00000008585 +8892 EIF2B2 MIM:606454|HGNC:HGNC:3258|Ensembl:ENSG00000119718|Vega:OTTHUMG00000171764 +8893 EIF2B5 MIM:603945|HGNC:HGNC:3261|Ensembl:ENSG00000145191|Vega:OTTHUMG00000156840 +8894 EIF2S2 MIM:603908|HGNC:HGNC:3266|Ensembl:ENSG00000125977|Vega:OTTHUMG00000032287 +8895 CPNE3 MIM:604207|HGNC:HGNC:2316|Ensembl:ENSG00000085719|Vega:OTTHUMG00000163725 +8896 BUD31 MIM:603477|HGNC:HGNC:29629|Ensembl:ENSG00000106245|Vega:OTTHUMG00000154602 +8897 MTMR3 MIM:603558|HGNC:HGNC:7451|Ensembl:ENSG00000100330|Vega:OTTHUMG00000151278 +8898 MTMR2 MIM:603557|HGNC:HGNC:7450|Ensembl:ENSG00000087053|Vega:OTTHUMG00000153837 +8899 PRPF4B MIM:602338|HGNC:HGNC:17346|Ensembl:ENSG00000112739|Vega:OTTHUMG00000014157 +8900 CCNA1 MIM:604036|HGNC:HGNC:1577|Ensembl:ENSG00000133101|Vega:OTTHUMG00000016733 +8904 CPNE1 MIM:604205|HGNC:HGNC:2314|Ensembl:ENSG00000214078|Vega:OTTHUMG00000032356 +8905 AP1S2 MIM:300629|HGNC:HGNC:560|Ensembl:ENSG00000182287|Vega:OTTHUMG00000021186 +8906 AP1G2 MIM:603534|HGNC:HGNC:556|Ensembl:ENSG00000213983|Vega:OTTHUMG00000028760 +8907 AP1M1 MIM:603535|HGNC:HGNC:13667|Ensembl:ENSG00000072958|Vega:OTTHUMG00000182323 +8908 GYG2 MIM:300198|HGNC:HGNC:4700|Ensembl:ENSG00000056998|Vega:OTTHUMG00000021079 +8909 ENDOU MIM:606720|HGNC:HGNC:14369|Ensembl:ENSG00000111405|Vega:OTTHUMG00000169670 +8910 SGCE MIM:604149|HGNC:HGNC:10808|Ensembl:ENSG00000127990|Vega:OTTHUMG00000022828 +8911 CACNA1I MIM:608230|HGNC:HGNC:1396|Ensembl:ENSG00000100346|Vega:OTTHUMG00000151096 +8912 CACNA1H MIM:607904|HGNC:HGNC:1395|Ensembl:ENSG00000196557|Vega:OTTHUMG00000172992 +8913 CACNA1G MIM:604065|HGNC:HGNC:1394|Ensembl:ENSG00000006283|Vega:OTTHUMG00000162180 +8914 TIMELESS MIM:603887|HGNC:HGNC:11813|Ensembl:ENSG00000111602|Vega:OTTHUMG00000170600 +8915 BCL10 MIM:603517|HGNC:HGNC:989|Ensembl:ENSG00000142867|Vega:OTTHUMG00000009965 +8916 HERC3 MIM:605200|HGNC:HGNC:4876|Ensembl:ENSG00000138641|Vega:OTTHUMG00000150436 +8917 HERC2P1 HGNC:HGNC:4869 +8918 HERC2P6 HGNC:HGNC:4874 +8924 HERC2 MIM:605837|HGNC:HGNC:4868|Ensembl:ENSG00000128731|Vega:OTTHUMG00000129251 +8925 HERC1 MIM:605109|HGNC:HGNC:4867|Ensembl:ENSG00000103657|Vega:OTTHUMG00000172433 +8926 SNURF HGNC:HGNC:11171|Ensembl:ENSG00000214265|Ensembl:ENSG00000273173|Vega:OTTHUMG00000129181|Vega:OTTHUMG00000186421 +8927 BSN MIM:604020|HGNC:HGNC:1117|Ensembl:ENSG00000164061|Vega:OTTHUMG00000133750 +8928 FOXH1 MIM:603621|HGNC:HGNC:3814|Ensembl:ENSG00000160973|Vega:OTTHUMG00000165172 +8929 PHOX2B MIM:603851|HGNC:HGNC:9143|Ensembl:ENSG00000109132|Vega:OTTHUMG00000099379 +8930 MBD4 MIM:603574|HGNC:HGNC:6919|Ensembl:ENSG00000129071|Vega:OTTHUMG00000159463 +8932 MBD2 MIM:603547|HGNC:HGNC:6917|Ensembl:ENSG00000134046|Vega:OTTHUMG00000132705 +8933 RTL8C MIM:300213|HGNC:HGNC:2569|Ensembl:ENSG00000134590|Vega:OTTHUMG00000022465 +8934 RAB29 MIM:603949|HGNC:HGNC:9789|Ensembl:ENSG00000117280|Vega:OTTHUMG00000035998 +8935 SKAP2 MIM:605215|HGNC:HGNC:15687|Ensembl:ENSG00000005020|Vega:OTTHUMG00000023495 +8936 WASF1 MIM:605035|HGNC:HGNC:12732|Ensembl:ENSG00000112290|Vega:OTTHUMG00000015357 +8938 BAIAP3 MIM:604009|HGNC:HGNC:948|Ensembl:ENSG00000007516|Vega:OTTHUMG00000047833 +8939 FUBP3 MIM:603536|HGNC:HGNC:4005|Ensembl:ENSG00000107164|Vega:OTTHUMG00000020809 +8940 TOP3B MIM:603582|HGNC:HGNC:11993|Ensembl:ENSG00000100038|Vega:OTTHUMG00000167438 +8941 CDK5R2 MIM:603764|HGNC:HGNC:1776|Ensembl:ENSG00000171450|Vega:OTTHUMG00000133083 +8942 KYNU MIM:605197|HGNC:HGNC:6469|Ensembl:ENSG00000115919|Vega:OTTHUMG00000131829 +8943 AP3D1 MIM:607246|HGNC:HGNC:568|Ensembl:ENSG00000065000|Vega:OTTHUMG00000180354 +8944 SNORD73A MIM:603568|HGNC:HGNC:10235|Ensembl:ENSG00000208797 +8945 BTRC MIM:603482|HGNC:HGNC:1144|Ensembl:ENSG00000166167|Vega:OTTHUMG00000018932 +8968 HIST1H3F MIM:602816|HGNC:HGNC:4773|Ensembl:ENSG00000277775|Vega:OTTHUMG00000014435 +8969 HIST1H2AG MIM:615012|HGNC:HGNC:4737|Ensembl:ENSG00000196787|Vega:OTTHUMG00000014469 +8970 HIST1H2BJ MIM:615044|HGNC:HGNC:4761|Ensembl:ENSG00000124635|Vega:OTTHUMG00000014470 +8971 H1FX MIM:602785|HGNC:HGNC:4722|Ensembl:ENSG00000184897|Vega:OTTHUMG00000159450 +8972 MGAM MIM:154360|HGNC:HGNC:7043|Ensembl:ENSG00000257335|Vega:OTTHUMG00000158395 +8973 CHRNA6 MIM:606888|HGNC:HGNC:15963|Ensembl:ENSG00000147434|Vega:OTTHUMG00000165275 +8974 P4HA2 MIM:600608|HGNC:HGNC:8547|Ensembl:ENSG00000072682|Vega:OTTHUMG00000059647 +8975 USP13 MIM:603591|HGNC:HGNC:12611|Ensembl:ENSG00000058056|Vega:OTTHUMG00000157783 +8976 WASL MIM:605056|HGNC:HGNC:12735|Ensembl:ENSG00000106299|Vega:OTTHUMG00000157346 +8985 PLOD3 MIM:603066|HGNC:HGNC:9083|Ensembl:ENSG00000106397|Vega:OTTHUMG00000157111 +8986 RPS6KA4 MIM:603606|HGNC:HGNC:10433|Ensembl:ENSG00000162302|Vega:OTTHUMG00000046094 +8987 STBD1 MIM:607406|HGNC:HGNC:24854|Ensembl:ENSG00000118804|Vega:OTTHUMG00000130109 +8988 HSPB3 MIM:604624|HGNC:HGNC:5248|Ensembl:ENSG00000169271|Vega:OTTHUMG00000096995 +8989 TRPA1 MIM:604775|HGNC:HGNC:497|Ensembl:ENSG00000104321|Vega:OTTHUMG00000164516 +8991 SELENBP1 MIM:604188|HGNC:HGNC:10719|Ensembl:ENSG00000143416|Vega:OTTHUMG00000012498 +8992 ATP6V0E1 MIM:603931|HGNC:HGNC:863|Ensembl:ENSG00000113732|Vega:OTTHUMG00000130518 +8993 PGLYRP1 MIM:604963|HGNC:HGNC:8904|Ensembl:ENSG00000008438|Vega:OTTHUMG00000182489 +8994 LIMD1 MIM:604543|HGNC:HGNC:6612|Ensembl:ENSG00000144791|Vega:OTTHUMG00000133453 +8995 TNFSF18 MIM:603898|HGNC:HGNC:11932|Ensembl:ENSG00000120337|Vega:OTTHUMG00000034835 +8996 NOL3 MIM:605235|HGNC:HGNC:7869|Ensembl:ENSG00000140939|Vega:OTTHUMG00000173316 +8997 KALRN MIM:604605|HGNC:HGNC:4814|Ensembl:ENSG00000160145|Vega:OTTHUMG00000125545 +8999 CDKL2 MIM:603442|HGNC:HGNC:1782|Ensembl:ENSG00000138769|Vega:OTTHUMG00000130103 +9001 HAP1 MIM:600947|HGNC:HGNC:4812|Ensembl:ENSG00000173805|Vega:OTTHUMG00000133498 +9002 F2RL3 MIM:602779|HGNC:HGNC:3540|Ensembl:ENSG00000127533|Vega:OTTHUMG00000182647 +9013 TAF1C MIM:604905|HGNC:HGNC:11534|Ensembl:ENSG00000103168|Vega:OTTHUMG00000176665 +9014 TAF1B MIM:604904|HGNC:HGNC:11533|Ensembl:ENSG00000115750|Vega:OTTHUMG00000151673 +9015 TAF1A MIM:604903|HGNC:HGNC:11532|Ensembl:ENSG00000143498|Vega:OTTHUMG00000037544 +9016 SLC25A14 MIM:300242|HGNC:HGNC:10984|Ensembl:ENSG00000102078|Vega:OTTHUMG00000022394 +9019 MPZL1 MIM:604376|HGNC:HGNC:7226|Ensembl:ENSG00000197965|Vega:OTTHUMG00000034571 +9020 MAP3K14 MIM:604655|HGNC:HGNC:6853|Ensembl:ENSG00000006062|Vega:OTTHUMG00000180364 +9021 SOCS3 MIM:604176|HGNC:HGNC:19391|Ensembl:ENSG00000184557|Vega:OTTHUMG00000177513 +9022 CLIC3 MIM:606533|HGNC:HGNC:2064|Ensembl:ENSG00000169583|Vega:OTTHUMG00000020954 +9023 CH25H MIM:604551|HGNC:HGNC:1907|Ensembl:ENSG00000138135|Vega:OTTHUMG00000018705 +9024 BRSK2 MIM:609236|HGNC:HGNC:11405|Ensembl:ENSG00000174672|Vega:OTTHUMG00000167089 +9025 RNF8 MIM:611685|HGNC:HGNC:10071|Ensembl:ENSG00000112130|Vega:OTTHUMG00000014620 +9026 HIP1R MIM:605613|HGNC:HGNC:18415|Ensembl:ENSG00000130787|Vega:OTTHUMG00000168765 +9027 NAT8 MIM:606716|HGNC:HGNC:18069|Ensembl:ENSG00000144035|Vega:OTTHUMG00000129818 +9028 RHBDL1 MIM:603264|HGNC:HGNC:10007|Ensembl:ENSG00000103269|Vega:OTTHUMG00000121141 +9030 ERDA1 MIM:603279|HGNC:HGNC:3442 +9031 BAZ1B MIM:605681|HGNC:HGNC:961|Ensembl:ENSG00000009954|Vega:OTTHUMG00000023847 +9032 TM4SF5 MIM:604657|HGNC:HGNC:11857|Ensembl:ENSG00000142484|Vega:OTTHUMG00000090776 +9033 PKD2L1 MIM:604532|HGNC:HGNC:9011|Ensembl:ENSG00000107593|Vega:OTTHUMG00000018910 +9034 CCRL2 MIM:608379|HGNC:HGNC:1612|Ensembl:ENSG00000121797|Vega:OTTHUMG00000156318 +9037 SEMA5A MIM:609297|HGNC:HGNC:10736|Ensembl:ENSG00000112902|Vega:OTTHUMG00000090501 +9038 TAAR5 MIM:607405|HGNC:HGNC:30236|Ensembl:ENSG00000135569|Vega:OTTHUMG00000015581 +9039 UBA3 MIM:603172|HGNC:HGNC:12470|Ensembl:ENSG00000144744|Vega:OTTHUMG00000154325 +9040 UBE2M MIM:603173|HGNC:HGNC:12491|Ensembl:ENSG00000130725|Vega:OTTHUMG00000183548 +9043 SPAG9 MIM:605430|HGNC:HGNC:14524|Ensembl:ENSG00000008294|Vega:OTTHUMG00000162316 +9044 BTAF1 MIM:605191|HGNC:HGNC:17307|Ensembl:ENSG00000095564|Vega:OTTHUMG00000018752 +9045 RPL14 MIM:617414|HGNC:HGNC:10305|Ensembl:ENSG00000188846|Vega:OTTHUMG00000156046 +9046 DOK2 MIM:604997|HGNC:HGNC:2991|Ensembl:ENSG00000147443|Vega:OTTHUMG00000131075 +9047 SH2D2A MIM:604514|HGNC:HGNC:10821|Ensembl:ENSG00000027869|Vega:OTTHUMG00000041305 +9048 ARTN MIM:603886|HGNC:HGNC:727|Ensembl:ENSG00000117407|Vega:OTTHUMG00000007705 +9049 AIP MIM:605555|HGNC:HGNC:358|Ensembl:ENSG00000110711|Vega:OTTHUMG00000167674 +9050 PSTPIP2 MIM:616046|HGNC:HGNC:9581|Ensembl:ENSG00000152229|Vega:OTTHUMG00000152674 +9051 PSTPIP1 MIM:606347|HGNC:HGNC:9580|Ensembl:ENSG00000140368|Vega:OTTHUMG00000172594 +9052 GPRC5A MIM:604138|HGNC:HGNC:9836|Ensembl:ENSG00000013588|Vega:OTTHUMG00000168710 +9053 MAP7 MIM:604108|HGNC:HGNC:6869|Ensembl:ENSG00000135525|Vega:OTTHUMG00000015646 +9054 NFS1 MIM:603485|HGNC:HGNC:15910|Ensembl:ENSG00000244005|Vega:OTTHUMG00000032361 +9055 PRC1 MIM:603484|HGNC:HGNC:9341|Ensembl:ENSG00000198901|Vega:OTTHUMG00000171685 +9056 SLC7A7 MIM:603593|HGNC:HGNC:11065|Ensembl:ENSG00000155465|Vega:OTTHUMG00000028692 +9057 SLC7A6 MIM:605641|HGNC:HGNC:11064|Ensembl:ENSG00000103064|Vega:OTTHUMG00000176544 +9058 SLC13A2 MIM:604148|HGNC:HGNC:10917|Ensembl:ENSG00000007216|Vega:OTTHUMG00000132523 +9060 PAPSS2 MIM:603005|HGNC:HGNC:8604|Ensembl:ENSG00000198682|Vega:OTTHUMG00000018683 +9061 PAPSS1 MIM:603262|HGNC:HGNC:8603|Ensembl:ENSG00000138801|Vega:OTTHUMG00000131210 +9063 PIAS2 MIM:603567|HGNC:HGNC:17311|Ensembl:ENSG00000078043|Vega:OTTHUMG00000179301 +9064 MAP3K6 MIM:604468|HGNC:HGNC:6858|Ensembl:ENSG00000142733|Vega:OTTHUMG00000004631 +9066 SYT7 MIM:604146|HGNC:HGNC:11514|Ensembl:ENSG00000011347|Vega:OTTHUMG00000168199 +9068 ANGPTL1 MIM:603874|HGNC:HGNC:489|Ensembl:ENSG00000116194|Vega:OTTHUMG00000035075 +9069 CLDN12 MIM:611232|HGNC:HGNC:2034|Ensembl:ENSG00000157224|Vega:OTTHUMG00000156612 +9070 ASH2L MIM:604782|HGNC:HGNC:744|Ensembl:ENSG00000129691|Vega:OTTHUMG00000164016 +9071 CLDN10 HGNC:HGNC:2033|Ensembl:ENSG00000134873|Vega:OTTHUMG00000017217 +9073 CLDN8 MIM:611231|HGNC:HGNC:2050|Ensembl:ENSG00000156284|Vega:OTTHUMG00000081872 +9074 CLDN6 MIM:615798|HGNC:HGNC:2048|Ensembl:ENSG00000184697|Vega:OTTHUMG00000128999 +9075 CLDN2 MIM:300520|HGNC:HGNC:2041|Ensembl:ENSG00000165376|Vega:OTTHUMG00000022154 +9076 CLDN1 MIM:603718|HGNC:HGNC:2032|Ensembl:ENSG00000163347|Vega:OTTHUMG00000156214 +9077 DIRAS3 MIM:605193|HGNC:HGNC:687|Ensembl:ENSG00000162595|Vega:OTTHUMG00000009544 +9079 LDB2 MIM:603450|HGNC:HGNC:6533|Ensembl:ENSG00000169744|Vega:OTTHUMG00000048212 +9080 CLDN9 MIM:615799|HGNC:HGNC:2051|Ensembl:ENSG00000213937|Vega:OTTHUMG00000129000 +9081 PRY MIM:400019|HGNC:HGNC:14024|Ensembl:ENSG00000169789|Vega:OTTHUMG00000043845 +9082 XKRY MIM:400015|HGNC:HGNC:18571 +9083 BPY2 MIM:400013|HGNC:HGNC:13508|Ensembl:ENSG00000183753|Vega:OTTHUMG00000058899 +9084 VCY MIM:400012|HGNC:HGNC:12668|Ensembl:ENSG00000129864|Vega:OTTHUMG00000036401 +9085 CDY1 MIM:400016|HGNC:HGNC:1809|Ensembl:ENSG00000172288|Vega:OTTHUMG00000045274 +9086 EIF1AY MIM:400014|HGNC:HGNC:3252|Ensembl:ENSG00000198692|Vega:OTTHUMG00000036544 +9087 TMSB4Y MIM:400017|HGNC:HGNC:11882|Ensembl:ENSG00000154620|Vega:OTTHUMG00000036366 +9088 PKMYT1 MIM:602474|HGNC:HGNC:29650|Ensembl:ENSG00000127564|Vega:OTTHUMG00000128975 +9091 PIGQ MIM:605754|HGNC:HGNC:14135|Ensembl:ENSG00000007541|Vega:OTTHUMG00000168047 +9092 SART1 MIM:605941|HGNC:HGNC:10538|Ensembl:ENSG00000175467|Vega:OTTHUMG00000166771 +9093 DNAJA3 MIM:608382|HGNC:HGNC:11808|Ensembl:ENSG00000103423|Vega:OTTHUMG00000129470 +9094 UNC119 MIM:604011|HGNC:HGNC:12565|Ensembl:ENSG00000109103|Vega:OTTHUMG00000132606 +9095 TBX19 MIM:604614|HGNC:HGNC:11596|Ensembl:ENSG00000143178|Vega:OTTHUMG00000034648 +9096 TBX18 MIM:604613|HGNC:HGNC:11595|Ensembl:ENSG00000112837|Vega:OTTHUMG00000015129 +9097 USP14 MIM:607274|HGNC:HGNC:12612|Ensembl:ENSG00000101557|Vega:OTTHUMG00000178040 +9098 USP6 MIM:604334|HGNC:HGNC:12629|Ensembl:ENSG00000129204|Vega:OTTHUMG00000099449 +9099 USP2 MIM:604725|HGNC:HGNC:12618|Ensembl:ENSG00000036672|Vega:OTTHUMG00000166200 +9100 USP10 MIM:609818|HGNC:HGNC:12608|Ensembl:ENSG00000103194|Vega:OTTHUMG00000176770 +9101 USP8 MIM:603158|HGNC:HGNC:12631|Ensembl:ENSG00000138592|Vega:OTTHUMG00000131645 +9103 FCGR2C MIM:612169|HGNC:HGNC:15626 +9104 RGN MIM:300212|HGNC:HGNC:9989|Ensembl:ENSG00000130988|Vega:OTTHUMG00000021435 +9107 MTMR6 MIM:603561|HGNC:HGNC:7453|Ensembl:ENSG00000139505|Vega:OTTHUMG00000016606 +9108 MTMR7 MIM:603562|HGNC:HGNC:7454|Ensembl:ENSG00000003987|Vega:OTTHUMG00000163771 +9110 MTMR4 MIM:603559|HGNC:HGNC:7452|Ensembl:ENSG00000108389|Vega:OTTHUMG00000179079 +9111 NMI MIM:603525|HGNC:HGNC:7854|Ensembl:ENSG00000123609|Vega:OTTHUMG00000131867 +9112 MTA1 MIM:603526|HGNC:HGNC:7410|Ensembl:ENSG00000182979|Vega:OTTHUMG00000150362 +9113 LATS1 MIM:603473|HGNC:HGNC:6514|Ensembl:ENSG00000131023|Vega:OTTHUMG00000016437 +9114 ATP6V0D1 MIM:607028|HGNC:HGNC:13724|Ensembl:ENSG00000159720|Vega:OTTHUMG00000137515 +9117 SEC22C MIM:604028|HGNC:HGNC:16828|Ensembl:ENSG00000093183|Vega:OTTHUMG00000131797 +9118 INA MIM:605338|HGNC:HGNC:6057|Ensembl:ENSG00000148798|Vega:OTTHUMG00000018986 +9119 KRT75 MIM:609025|HGNC:HGNC:24431|Ensembl:ENSG00000170454|Vega:OTTHUMG00000169592 +9120 SLC16A6 MIM:603880|HGNC:HGNC:10927|Ensembl:ENSG00000108932|Vega:OTTHUMG00000179812 +9121 SLC16A5 MIM:603879|HGNC:HGNC:10926|Ensembl:ENSG00000170190|Vega:OTTHUMG00000179277 +9122 SLC16A4 MIM:603878|HGNC:HGNC:10925|Ensembl:ENSG00000168679|Vega:OTTHUMG00000011285 +9123 SLC16A3 MIM:603877|HGNC:HGNC:10924|Ensembl:ENSG00000141526|Vega:OTTHUMG00000178832 +9124 PDLIM1 MIM:605900|HGNC:HGNC:2067|Ensembl:ENSG00000107438|Vega:OTTHUMG00000018810 +9125 CNOT9 MIM:612054|HGNC:HGNC:10445|Ensembl:ENSG00000144580|Vega:OTTHUMG00000154750 +9126 SMC3 MIM:606062|HGNC:HGNC:2468|Ensembl:ENSG00000108055|Vega:OTTHUMG00000019042 +9127 P2RX6 MIM:608077|HGNC:HGNC:8538|Ensembl:ENSG00000099957|Vega:OTTHUMG00000150689 +9128 PRPF4 MIM:607795|HGNC:HGNC:17349|Ensembl:ENSG00000136875|Vega:OTTHUMG00000020517 +9129 PRPF3 MIM:607301|HGNC:HGNC:17348|Ensembl:ENSG00000117360|Vega:OTTHUMG00000012807 +9130 FAM50A MIM:300453|HGNC:HGNC:18786|Ensembl:ENSG00000071859|Vega:OTTHUMG00000033292 +9131 AIFM1 MIM:300169|MIM:310490|HGNC:HGNC:8768|Ensembl:ENSG00000156709|Vega:OTTHUMG00000022392 +9132 KCNQ4 MIM:603537|HGNC:HGNC:6298|Ensembl:ENSG00000117013|Vega:OTTHUMG00000007730 +9133 CCNB2 MIM:602755|HGNC:HGNC:1580|Ensembl:ENSG00000157456|Vega:OTTHUMG00000132715 +9134 CCNE2 MIM:603775|HGNC:HGNC:1590|Ensembl:ENSG00000175305|Vega:OTTHUMG00000164696 +9135 RABEP1 MIM:603616|HGNC:HGNC:17677|Ensembl:ENSG00000029725|Vega:OTTHUMG00000177870 +9136 RRP9 HGNC:HGNC:16829|Ensembl:ENSG00000114767|Vega:OTTHUMG00000156930 +9138 ARHGEF1 MIM:601855|HGNC:HGNC:681|Ensembl:ENSG00000076928|Vega:OTTHUMG00000182679 +9139 CBFA2T2 MIM:603672|HGNC:HGNC:1536|Ensembl:ENSG00000078699|Vega:OTTHUMG00000032261 +9140 ATG12 MIM:609608|HGNC:HGNC:588|Ensembl:ENSG00000145782|Vega:OTTHUMG00000128889 +9141 PDCD5 MIM:604583|HGNC:HGNC:8764|Ensembl:ENSG00000105185|Vega:OTTHUMG00000180224 +9142 TMEM257 MIM:300565|HGNC:HGNC:2562|Ensembl:ENSG00000221870|Vega:OTTHUMG00000159605 +9143 SYNGR3 MIM:603927|HGNC:HGNC:11501|Ensembl:ENSG00000127561|Vega:OTTHUMG00000128711 +9144 SYNGR2 MIM:603926|HGNC:HGNC:11499|Ensembl:ENSG00000108639|Vega:OTTHUMG00000177457 +9145 SYNGR1 MIM:603925|HGNC:HGNC:11498|Ensembl:ENSG00000100321|Vega:OTTHUMG00000030978 +9146 HGS MIM:604375|HGNC:HGNC:4897|Ensembl:ENSG00000185359|Vega:OTTHUMG00000178109 +9147 NEMF MIM:608378|HGNC:HGNC:10663|Ensembl:ENSG00000165525|Vega:OTTHUMG00000170857 +9148 NEURL1 MIM:603804|HGNC:HGNC:7761|Ensembl:ENSG00000107954|Vega:OTTHUMG00000018995 +9149 DYRK1B MIM:604556|HGNC:HGNC:3092|Ensembl:ENSG00000105204|Vega:OTTHUMG00000182584 +9150 CTDP1 MIM:604927|HGNC:HGNC:2498|Ensembl:ENSG00000060069|Vega:OTTHUMG00000132920 +9152 SLC6A5 MIM:604159|HGNC:HGNC:11051|Ensembl:ENSG00000165970|Vega:OTTHUMG00000166024 +9153 SLC28A2 MIM:606208|HGNC:HGNC:11002|Ensembl:ENSG00000137860|Vega:OTTHUMG00000131426 +9154 SLC28A1 MIM:606207|HGNC:HGNC:11001|Ensembl:ENSG00000156222|Vega:OTTHUMG00000148668 +9156 EXO1 MIM:606063|HGNC:HGNC:3511|Ensembl:ENSG00000174371|Vega:OTTHUMG00000039965 +9158 FIBP MIM:608296|HGNC:HGNC:3705|Ensembl:ENSG00000172500|Vega:OTTHUMG00000166846 +9159 PCSK7 MIM:604872|HGNC:HGNC:8748|Ensembl:ENSG00000160613|Vega:OTTHUMG00000165640 +9162 DGKI MIM:604072|HGNC:HGNC:2855|Ensembl:ENSG00000157680|Vega:OTTHUMG00000155697 +9163 AMLCR2 MIM:602439|HGNC:HGNC:466 +9166 EBAG9 MIM:605772|HGNC:HGNC:3123|Ensembl:ENSG00000147654|Vega:OTTHUMG00000165346 +9167 COX7A2L MIM:605771|HGNC:HGNC:2289|Ensembl:ENSG00000115944|Vega:OTTHUMG00000128605 +9168 TMSB10 MIM:188399|HGNC:HGNC:11879|Ensembl:ENSG00000034510|Vega:OTTHUMG00000130027 +9169 SCAF11 MIM:603668|HGNC:HGNC:10784|Ensembl:ENSG00000139218|Vega:OTTHUMG00000149930 +9170 LPAR2 MIM:605110|HGNC:HGNC:3168|Ensembl:ENSG00000064547|Vega:OTTHUMG00000182328 +9172 MYOM2 MIM:603509|HGNC:HGNC:7614|Ensembl:ENSG00000036448|Vega:OTTHUMG00000129175 +9173 IL1RL1 MIM:601203|HGNC:HGNC:5998|Ensembl:ENSG00000115602|Vega:OTTHUMG00000130782 +9175 MAP3K13 MIM:604915|HGNC:HGNC:6852|Ensembl:ENSG00000073803|Vega:OTTHUMG00000156673 +9177 HTR3B MIM:604654|HGNC:HGNC:5298|Ensembl:ENSG00000149305|Vega:OTTHUMG00000168210 +9179 AP4M1 MIM:602296|HGNC:HGNC:574|Ensembl:ENSG00000221838|Vega:OTTHUMG00000154722 +9180 OSMR MIM:601743|HGNC:HGNC:8507|Ensembl:ENSG00000145623|Vega:OTTHUMG00000090811 +9181 ARHGEF2 MIM:607560|HGNC:HGNC:682|Ensembl:ENSG00000116584|Vega:OTTHUMG00000017464 +9182 RASSF9 MIM:610383|HGNC:HGNC:15739|Ensembl:ENSG00000198774|Vega:OTTHUMG00000169831 +9183 ZW10 MIM:603954|HGNC:HGNC:13194|Ensembl:ENSG00000086827|Vega:OTTHUMG00000168190 +9184 BUB3 MIM:603719|HGNC:HGNC:1151|Ensembl:ENSG00000154473|Vega:OTTHUMG00000019197 +9185 REPS2 MIM:300317|HGNC:HGNC:9963|Ensembl:ENSG00000169891|Vega:OTTHUMG00000021199 +9187 SLC24A1 MIM:603617|HGNC:HGNC:10975|Ensembl:ENSG00000074621|Vega:OTTHUMG00000167960 +9188 DDX21 MIM:606357|HGNC:HGNC:2744|Ensembl:ENSG00000165732|Vega:OTTHUMG00000018366 +9189 ZBED1 MIM:300178|HGNC:HGNC:447|Ensembl:ENSG00000214717|Vega:OTTHUMG00000021069 +9191 DEDD MIM:606841|HGNC:HGNC:2755|Ensembl:ENSG00000158796|Vega:OTTHUMG00000033104 +9193 SPG9 MIM:601162|HGNC:HGNC:11239 +9194 SLC16A7 MIM:603654|HGNC:HGNC:10928|Ensembl:ENSG00000118596|Vega:OTTHUMG00000169923 +9196 KCNAB3 MIM:604111|HGNC:HGNC:6230|Ensembl:ENSG00000170049|Vega:OTTHUMG00000108170 +9197 SLC33A1 MIM:603690|HGNC:HGNC:95|Ensembl:ENSG00000169359|Vega:OTTHUMG00000158481 +9200 HACD1 MIM:610467|HGNC:HGNC:9639|Ensembl:ENSG00000165996|Vega:OTTHUMG00000017750 +9201 DCLK1 MIM:604742|HGNC:HGNC:2700|Ensembl:ENSG00000133083|Vega:OTTHUMG00000016729 +9202 ZMYM4 MIM:613568|HGNC:HGNC:13055|Ensembl:ENSG00000146463|Vega:OTTHUMG00000004241 +9203 ZMYM3 MIM:300061|HGNC:HGNC:13054|Ensembl:ENSG00000147130|Vega:OTTHUMG00000021799 +9204 ZMYM6 MIM:613567|HGNC:HGNC:13050|Ensembl:ENSG00000163867|Vega:OTTHUMG00000004163 +9205 ZMYM5 MIM:616443|HGNC:HGNC:13029|Ensembl:ENSG00000132950|Vega:OTTHUMG00000016504 +9206 RAD17P2 HGNC:HGNC:9809 +9207 RAD17P1 HGNC:HGNC:9808 +9208 LRRFIP1 MIM:603256|HGNC:HGNC:6702|Ensembl:ENSG00000124831|Vega:OTTHUMG00000133339 +9209 LRRFIP2 MIM:614043|HGNC:HGNC:6703|Ensembl:ENSG00000093167|Vega:OTTHUMG00000130796 +9210 BMP15 MIM:300247|HGNC:HGNC:1068|Ensembl:ENSG00000130385|Vega:OTTHUMG00000021525 +9211 LGI1 MIM:604619|HGNC:HGNC:6572|Ensembl:ENSG00000108231|Vega:OTTHUMG00000018777 +9212 AURKB MIM:604970|HGNC:HGNC:11390|Ensembl:ENSG00000178999|Vega:OTTHUMG00000108189 +9213 XPR1 MIM:605237|HGNC:HGNC:12827|Ensembl:ENSG00000143324|Vega:OTTHUMG00000035116 +9214 FCMR MIM:606015|HGNC:HGNC:14315|Ensembl:ENSG00000162894|Vega:OTTHUMG00000036457 +9215 LARGE1 MIM:603590|HGNC:HGNC:6511|Ensembl:ENSG00000133424|Vega:OTTHUMG00000150914 +9217 VAPB MIM:605704|HGNC:HGNC:12649|Ensembl:ENSG00000124164|Vega:OTTHUMG00000032840 +9218 VAPA MIM:605703|HGNC:HGNC:12648|Ensembl:ENSG00000101558|Vega:OTTHUMG00000131603 +9219 MTA2 MIM:603947|HGNC:HGNC:7411|Ensembl:ENSG00000149480|Vega:OTTHUMG00000167684 +9220 TIAF1 MIM:609517|HGNC:HGNC:11803|Ensembl:ENSG00000221995|Vega:OTTHUMG00000163268 +9221 NOLC1 MIM:602394|HGNC:HGNC:15608|Ensembl:ENSG00000166197|Vega:OTTHUMG00000018944 +9223 MAGI1 MIM:602625|HGNC:HGNC:946|Ensembl:ENSG00000151276|Vega:OTTHUMG00000157554 +9227 LRAT MIM:604863|HGNC:HGNC:6685|Ensembl:ENSG00000121207|Vega:OTTHUMG00000161418 +9228 DLGAP2 MIM:605438|HGNC:HGNC:2906|Ensembl:ENSG00000198010|Vega:OTTHUMG00000163599 +9229 DLGAP1 MIM:605445|HGNC:HGNC:2905|Ensembl:ENSG00000170579|Vega:OTTHUMG00000131537 +9230 RAB11B MIM:604198|HGNC:HGNC:9761|Ensembl:ENSG00000185236|Vega:OTTHUMG00000182278 +9231 DLG5 MIM:604090|HGNC:HGNC:2904|Ensembl:ENSG00000151208|Vega:OTTHUMG00000018548 +9232 PTTG1 MIM:604147|HGNC:HGNC:9690|Ensembl:ENSG00000164611|Vega:OTTHUMG00000130328 +9235 IL32 MIM:606001|HGNC:HGNC:16830|Ensembl:ENSG00000008517|Vega:OTTHUMG00000167498 +9236 CCPG1 MIM:611326|HGNC:HGNC:24227|Ensembl:ENSG00000260916|Vega:OTTHUMG00000172678 +9238 TBRG4 MIM:611325|HGNC:HGNC:17443|Ensembl:ENSG00000136270|Vega:OTTHUMG00000129247 +9240 PNMA1 MIM:604010|HGNC:HGNC:9158|Ensembl:ENSG00000176903|Vega:OTTHUMG00000169183 +9241 NOG MIM:602991|HGNC:HGNC:7866|Ensembl:ENSG00000183691|Vega:OTTHUMG00000151770 +9242 MSC MIM:603628|HGNC:HGNC:7321|Ensembl:ENSG00000178860|Vega:OTTHUMG00000164489 +9244 CRLF1 MIM:604237|HGNC:HGNC:2364|Ensembl:ENSG00000006016|Vega:OTTHUMG00000183111 +9245 GCNT3 MIM:606836|HGNC:HGNC:4205|Ensembl:ENSG00000140297|Vega:OTTHUMG00000132726 +9246 UBE2L6 MIM:603890|HGNC:HGNC:12490|Ensembl:ENSG00000156587|Vega:OTTHUMG00000167047 +9247 GCM2 MIM:603716|HGNC:HGNC:4198|Ensembl:ENSG00000124827|Vega:OTTHUMG00000014249 +9248 GPR50 MIM:300207|HGNC:HGNC:4506|Ensembl:ENSG00000102195|Vega:OTTHUMG00000024166 +9249 DHRS3 MIM:612830|HGNC:HGNC:17693|Ensembl:ENSG00000162496|Vega:OTTHUMG00000001885 +9252 RPS6KA5 MIM:603607|HGNC:HGNC:10434|Ensembl:ENSG00000100784|Vega:OTTHUMG00000171055 +9253 NUMBL MIM:604018|HGNC:HGNC:8061|Ensembl:ENSG00000105245|Vega:OTTHUMG00000182627 +9254 CACNA2D2 MIM:607082|HGNC:HGNC:1400|Ensembl:ENSG00000007402|Vega:OTTHUMG00000156887 +9255 AIMP1 MIM:603605|HGNC:HGNC:10648|Ensembl:ENSG00000164022|Vega:OTTHUMG00000131217 +9256 TSPOAP1 MIM:610764|HGNC:HGNC:16831|Ensembl:ENSG00000005379|Vega:OTTHUMG00000178923 +9258 MFHAS1 MIM:605352|HGNC:HGNC:16982|Ensembl:ENSG00000147324|Vega:OTTHUMG00000163676 +9260 PDLIM7 MIM:605903|HGNC:HGNC:22958|Ensembl:ENSG00000196923|Vega:OTTHUMG00000130853 +9261 MAPKAPK2 MIM:602006|HGNC:HGNC:6887|Ensembl:ENSG00000162889|Vega:OTTHUMG00000036342 +9262 STK17B MIM:604727|HGNC:HGNC:11396|Ensembl:ENSG00000081320|Vega:OTTHUMG00000132735 +9263 STK17A MIM:604726|HGNC:HGNC:11395|Ensembl:ENSG00000164543|Vega:OTTHUMG00000022825 +9265 CYTH3 MIM:605081|HGNC:HGNC:9504|Ensembl:ENSG00000008256|Vega:OTTHUMG00000023440 +9266 CYTH2 MIM:602488|HGNC:HGNC:9502|Ensembl:ENSG00000105443|Vega:OTTHUMG00000150245 +9267 CYTH1 MIM:182115|HGNC:HGNC:9501|Ensembl:ENSG00000108669|Vega:OTTHUMG00000150253 +9270 ITGB1BP1 MIM:607153|HGNC:HGNC:23927|Ensembl:ENSG00000119185|Vega:OTTHUMG00000090414 +9271 PIWIL1 MIM:605571|HGNC:HGNC:9007|Ensembl:ENSG00000125207|Vega:OTTHUMG00000168382 +9274 BCL7C MIM:605847|HGNC:HGNC:1006|Ensembl:ENSG00000099385|Vega:OTTHUMG00000177719 +9275 BCL7B MIM:605846|HGNC:HGNC:1005|Ensembl:ENSG00000106635|Vega:OTTHUMG00000023412 +9276 COPB2 MIM:606990|HGNC:HGNC:2232|Ensembl:ENSG00000184432|Vega:OTTHUMG00000159959 +9277 WDR46 MIM:611440|HGNC:HGNC:13923|Ensembl:ENSG00000227057|Vega:OTTHUMG00000031192 +9278 ZBTB22 MIM:611439|HGNC:HGNC:13085|Ensembl:ENSG00000236104|Vega:OTTHUMG00000031110 +9282 MED14 MIM:300182|HGNC:HGNC:2370|Ensembl:ENSG00000180182|Vega:OTTHUMG00000024107 +9283 GPR37L1 HGNC:HGNC:14923|Ensembl:ENSG00000170075|Vega:OTTHUMG00000035924 +9284 NPIPA1 MIM:606406|HGNC:HGNC:7909|Ensembl:ENSG00000183426|Vega:OTTHUMG00000090663 +9287 TAAR2 MIM:604849|HGNC:HGNC:4514|Ensembl:ENSG00000146378|Vega:OTTHUMG00000015585 +9288 TAAR3P HGNC:HGNC:4513|Ensembl:ENSG00000179073 +9289 ADGRG1 MIM:604110|HGNC:HGNC:4512|Ensembl:ENSG00000205336|Vega:OTTHUMG00000176742 +9290 GPR55 MIM:604107|HGNC:HGNC:4511|Ensembl:ENSG00000135898|Vega:OTTHUMG00000133224 +9292 GPR53P HGNC:HGNC:4509 +9293 GPR52 MIM:604106|HGNC:HGNC:4508|Ensembl:ENSG00000203737|Vega:OTTHUMG00000034901 +9294 S1PR2 MIM:605111|HGNC:HGNC:3169|Ensembl:ENSG00000267534|Vega:OTTHUMG00000180399 +9295 SRSF11 MIM:602010|HGNC:HGNC:10782|Ensembl:ENSG00000116754|Vega:OTTHUMG00000009342 +9296 ATP6V1F MIM:607160|HGNC:HGNC:16832|Ensembl:ENSG00000128524|Vega:OTTHUMG00000158365 +9297 SNORD29 MIM:603228|HGNC:HGNC:10151 +9298 SNORD31 MIM:603230|HGNC:HGNC:10158 +9299 SNORD30 MIM:603229|HGNC:HGNC:10157|Ensembl:ENSG00000277846 +9300 SNORD28 MIM:603227|HGNC:HGNC:10150|Ensembl:ENSG00000274544 +9301 SNORD27 MIM:603226|HGNC:HGNC:10149|Ensembl:ENSG00000275996 +9302 SNORD26 MIM:603225|HGNC:HGNC:10148|Ensembl:ENSG00000276788 +9303 SNORD25 MIM:603224|HGNC:HGNC:10147|Ensembl:ENSG00000275043 +9304 SNORD22 MIM:603223|HGNC:HGNC:10145|Ensembl:ENSG00000277194 +9306 SOCS6 MIM:605118|HGNC:HGNC:16833|Ensembl:ENSG00000170677|Vega:OTTHUMG00000132816 +9308 CD83 MIM:604534|HGNC:HGNC:1703|Ensembl:ENSG00000112149|Vega:OTTHUMG00000014283 +9310 ZNF235 MIM:604749|HGNC:HGNC:12866|Ensembl:ENSG00000159917|Vega:OTTHUMG00000182353 +9311 ASIC3 MIM:611741|HGNC:HGNC:101|Ensembl:ENSG00000213199|Vega:OTTHUMG00000158685 +9312 KCNB2 MIM:607738|HGNC:HGNC:6232|Ensembl:ENSG00000182674|Vega:OTTHUMG00000164498 +9313 MMP20 MIM:604629|HGNC:HGNC:7167|Ensembl:ENSG00000137674|Vega:OTTHUMG00000168081 +9314 KLF4 MIM:602253|HGNC:HGNC:6348|Ensembl:ENSG00000136826|Vega:OTTHUMG00000020449 +9315 NREP MIM:607332|HGNC:HGNC:16834|Ensembl:ENSG00000134986|Vega:OTTHUMG00000128795 +9317 PTER MIM:604446|HGNC:HGNC:9590|Ensembl:ENSG00000165983|Vega:OTTHUMG00000017737 +9318 COPS2 MIM:604508|HGNC:HGNC:30747|Ensembl:ENSG00000166200|Vega:OTTHUMG00000172324 +9319 TRIP13 MIM:604507|HGNC:HGNC:12307|Ensembl:ENSG00000071539|Vega:OTTHUMG00000090349 +9320 TRIP12 MIM:604506|HGNC:HGNC:12306|Ensembl:ENSG00000153827|Vega:OTTHUMG00000153623 +9321 TRIP11 MIM:604505|HGNC:HGNC:12305|Ensembl:ENSG00000100815|Vega:OTTHUMG00000171128 +9322 TRIP10 MIM:604504|HGNC:HGNC:12304|Ensembl:ENSG00000125733|Vega:OTTHUMG00000150255 +9324 HMGN3 MIM:604502|HGNC:HGNC:12312|Ensembl:ENSG00000118418|Vega:OTTHUMG00000015073 +9325 TRIP4 MIM:604501|HGNC:HGNC:12310|Ensembl:ENSG00000103671|Vega:OTTHUMG00000133033 +9326 ZNHIT3 MIM:604500|HGNC:HGNC:12309|Ensembl:ENSG00000273611|Vega:OTTHUMG00000188436 +9328 GTF3C5 MIM:604890|HGNC:HGNC:4668|Ensembl:ENSG00000148308|Vega:OTTHUMG00000020856 +9329 GTF3C4 MIM:604892|HGNC:HGNC:4667|Ensembl:ENSG00000125484|Vega:OTTHUMG00000020842 +9330 GTF3C3 MIM:604888|HGNC:HGNC:4666|Ensembl:ENSG00000119041|Vega:OTTHUMG00000154633 +9331 B4GALT6 MIM:604017|HGNC:HGNC:929|Ensembl:ENSG00000118276|Vega:OTTHUMG00000131980 +9332 CD163 MIM:605545|HGNC:HGNC:1631|Ensembl:ENSG00000177575|Vega:OTTHUMG00000168353 +9333 TGM5 MIM:603805|HGNC:HGNC:11781|Ensembl:ENSG00000104055|Vega:OTTHUMG00000176488 +9334 B4GALT5 MIM:604016|HGNC:HGNC:928|Ensembl:ENSG00000158470|Vega:OTTHUMG00000033086 +9337 CNOT8 MIM:603731|HGNC:HGNC:9207|Ensembl:ENSG00000155508|Vega:OTTHUMG00000130192 +9338 TCEAL1 MIM:300237|HGNC:HGNC:11616|Ensembl:ENSG00000172465|Vega:OTTHUMG00000022699 +9340 GLP2R MIM:603659|HGNC:HGNC:4325|Ensembl:ENSG00000065325|Vega:OTTHUMG00000130269 +9341 VAMP3 MIM:603657|HGNC:HGNC:12644|Ensembl:ENSG00000049245|Vega:OTTHUMG00000001225 +9342 SNAP29 MIM:604202|HGNC:HGNC:11133|Ensembl:ENSG00000099940|Vega:OTTHUMG00000150765 +9343 EFTUD2 MIM:603892|HGNC:HGNC:30858|Ensembl:ENSG00000108883|Vega:OTTHUMG00000179865 +9344 TAOK2 MIM:613199|HGNC:HGNC:16835|Ensembl:ENSG00000149930|Vega:OTTHUMG00000132111 +9348 NDST3 MIM:603950|HGNC:HGNC:7682|Ensembl:ENSG00000164100|Vega:OTTHUMG00000132959 +9349 RPL23 MIM:603662|HGNC:HGNC:10316|Ensembl:ENSG00000125691|Vega:OTTHUMG00000133118 +9350 CER1 MIM:603777|HGNC:HGNC:1862|Ensembl:ENSG00000147869|Vega:OTTHUMG00000021022 +9351 SLC9A3R2 MIM:606553|HGNC:HGNC:11076|Ensembl:ENSG00000065054|Vega:OTTHUMG00000176956 +9352 TXNL1 MIM:603049|HGNC:HGNC:12436|Ensembl:ENSG00000091164|Vega:OTTHUMG00000132722 +9353 SLIT2 MIM:603746|HGNC:HGNC:11086|Ensembl:ENSG00000145147|Vega:OTTHUMG00000128551 +9354 UBE4A MIM:603753|HGNC:HGNC:12499|Ensembl:ENSG00000110344|Vega:OTTHUMG00000168100 +9355 LHX2 MIM:603759|HGNC:HGNC:6594|Ensembl:ENSG00000106689|Vega:OTTHUMG00000020647 +9356 SLC22A6 MIM:607582|HGNC:HGNC:10970|Ensembl:ENSG00000197901|Vega:OTTHUMG00000167767 +9358 ITGBL1 MIM:604234|HGNC:HGNC:6164|Ensembl:ENSG00000198542|Vega:OTTHUMG00000017296 +9360 PPIG MIM:606093|HGNC:HGNC:14650|Ensembl:ENSG00000138398|Vega:OTTHUMG00000132206 +9361 LONP1 MIM:605490|HGNC:HGNC:9479|Ensembl:ENSG00000196365|Vega:OTTHUMG00000180504 +9362 CPNE6 MIM:605688|HGNC:HGNC:2319|Ensembl:ENSG00000100884|Vega:OTTHUMG00000028781 +9363 RAB33A MIM:300333|HGNC:HGNC:9773|Ensembl:ENSG00000134594|Vega:OTTHUMG00000022391 +9364 RAB28 MIM:612994|HGNC:HGNC:9768|Ensembl:ENSG00000157869|Vega:OTTHUMG00000090543 +9365 KL MIM:604824|HGNC:HGNC:6344|Ensembl:ENSG00000133116|Vega:OTTHUMG00000017408 +9366 RAB9BP1 HGNC:HGNC:9793|Ensembl:ENSG00000232159 +9367 RAB9A MIM:300284|HGNC:HGNC:9792|Ensembl:ENSG00000123595|Vega:OTTHUMG00000021156 +9368 SLC9A3R1 MIM:604990|HGNC:HGNC:11075|Ensembl:ENSG00000109062|Vega:OTTHUMG00000178863 +9369 NRXN3 MIM:600567|HGNC:HGNC:8010|Ensembl:ENSG00000021645|Vega:OTTHUMG00000171502 +9370 ADIPOQ MIM:605441|HGNC:HGNC:13633|Ensembl:ENSG00000181092|Vega:OTTHUMG00000156521 +9371 KIF3B MIM:603754|HGNC:HGNC:6320|Ensembl:ENSG00000101350|Vega:OTTHUMG00000032214 +9372 ZFYVE9 MIM:603755|HGNC:HGNC:6775|Ensembl:ENSG00000157077|Vega:OTTHUMG00000008061 +9373 PLAA MIM:603873|HGNC:HGNC:9043|Ensembl:ENSG00000137055|Vega:OTTHUMG00000019708 +9374 PPT2 MIM:603298|HGNC:HGNC:9326|Ensembl:ENSG00000221988|Vega:OTTHUMG00000031257 +9375 TM9SF2 MIM:604678|HGNC:HGNC:11865|Ensembl:ENSG00000125304|Vega:OTTHUMG00000017272 +9376 SLC22A8 MIM:607581|HGNC:HGNC:10972|Ensembl:ENSG00000149452|Vega:OTTHUMG00000167768 +9377 COX5A MIM:603773|HGNC:HGNC:2267|Ensembl:ENSG00000178741|Vega:OTTHUMG00000142825 +9378 NRXN1 MIM:600565|HGNC:HGNC:8008|Ensembl:ENSG00000179915|Vega:OTTHUMG00000129263 +9379 NRXN2 MIM:600566|HGNC:HGNC:8009|Ensembl:ENSG00000110076|Vega:OTTHUMG00000045214 +9380 GRHPR MIM:604296|HGNC:HGNC:4570|Ensembl:ENSG00000137106|Vega:OTTHUMG00000019914 +9381 OTOF MIM:603681|HGNC:HGNC:8515|Ensembl:ENSG00000115155|Vega:OTTHUMG00000096977 +9382 COG1 MIM:606973|HGNC:HGNC:6545|Ensembl:ENSG00000166685|Vega:OTTHUMG00000178344 +9383 TSIX MIM:300181|HGNC:HGNC:12377|Ensembl:ENSG00000270641 +9384 COX6CP1 HGNC:HGNC:2286 +9385 COX5AP1 HGNC:HGNC:2268 +9386 COX7CP1 HGNC:HGNC:2293 +9388 LIPG MIM:603684|HGNC:HGNC:6623|Ensembl:ENSG00000101670|Vega:OTTHUMG00000179658 +9389 SLC22A14 MIM:604048|HGNC:HGNC:8495|Ensembl:ENSG00000144671|Vega:OTTHUMG00000131082 +9390 SLC22A13 MIM:604047|HGNC:HGNC:8494|Ensembl:ENSG00000172940|Vega:OTTHUMG00000131086 +9391 CIAO1 MIM:604333|HGNC:HGNC:14280|Ensembl:ENSG00000144021|Vega:OTTHUMG00000130452 +9392 TGFBRAP1 MIM:606237|HGNC:HGNC:16836|Ensembl:ENSG00000135966|Vega:OTTHUMG00000130809 +9394 HS6ST1 MIM:604846|HGNC:HGNC:5201|Ensembl:ENSG00000136720|Vega:OTTHUMG00000153542 +9397 NMT2 MIM:603801|HGNC:HGNC:7858|Ensembl:ENSG00000152465|Vega:OTTHUMG00000017723 +9398 CD101 MIM:604516|HGNC:HGNC:5949|Ensembl:ENSG00000134256|Vega:OTTHUMG00000012029 +9399 STOML1 MIM:608326|HGNC:HGNC:14560|Ensembl:ENSG00000067221|Vega:OTTHUMG00000137608 +9400 RECQL5 MIM:603781|HGNC:HGNC:9950|Ensembl:ENSG00000108469|Vega:OTTHUMG00000179795 +9401 RECQL4 MIM:603780|HGNC:HGNC:9949|Ensembl:ENSG00000160957|Vega:OTTHUMG00000165178 +9402 GRAP2 MIM:604518|HGNC:HGNC:4563|Ensembl:ENSG00000100351|Vega:OTTHUMG00000151097 +9403 SELENOF MIM:606254|HGNC:HGNC:17705|Ensembl:ENSG00000183291|Vega:OTTHUMG00000008520 +9404 LPXN MIM:605390|HGNC:HGNC:14061|Ensembl:ENSG00000110031|Vega:OTTHUMG00000167466 +9406 ZRANB2 MIM:604347|HGNC:HGNC:13058|Ensembl:ENSG00000132485|Vega:OTTHUMG00000009660 +9407 TMPRSS11D MIM:605369|HGNC:HGNC:24059|Ensembl:ENSG00000153802|Vega:OTTHUMG00000129300 +9409 PEX16 MIM:603360|HGNC:HGNC:8857|Ensembl:ENSG00000121680|Vega:OTTHUMG00000167005 +9410 SNRNP40 MIM:607797|HGNC:HGNC:30857|Ensembl:ENSG00000060688|Vega:OTTHUMG00000003790 +9411 ARHGAP29 MIM:610496|HGNC:HGNC:30207|Ensembl:ENSG00000137962|Vega:OTTHUMG00000010643 +9412 MED21 MIM:603800|HGNC:HGNC:11473|Ensembl:ENSG00000152944|Vega:OTTHUMG00000169276 +9413 FAM189A2 MIM:607710|HGNC:HGNC:24820|Ensembl:ENSG00000135063|Vega:OTTHUMG00000019979 +9414 TJP2 MIM:607709|HGNC:HGNC:11828|Ensembl:ENSG00000119139|Vega:OTTHUMG00000019978 +9415 FADS2 MIM:606149|HGNC:HGNC:3575|Ensembl:ENSG00000134824|Vega:OTTHUMG00000163794 +9416 DDX23 MIM:612172|HGNC:HGNC:17347|Ensembl:ENSG00000174243|Vega:OTTHUMG00000170399 +9419 CRIPT MIM:604594|HGNC:HGNC:14312|Ensembl:ENSG00000119878|Vega:OTTHUMG00000128815 +9420 CYP7B1 MIM:603711|HGNC:HGNC:2652|Ensembl:ENSG00000172817|Vega:OTTHUMG00000164387 +9421 HAND1 MIM:602406|HGNC:HGNC:4807|Ensembl:ENSG00000113196|Vega:OTTHUMG00000130193 +9422 ZNF264 MIM:604668|HGNC:HGNC:13057|Ensembl:ENSG00000083844|Vega:OTTHUMG00000183104 +9423 NTN1 MIM:601614|HGNC:HGNC:8029|Ensembl:ENSG00000065320|Vega:OTTHUMG00000130257 +9424 KCNK6 MIM:603939|HGNC:HGNC:6281|Ensembl:ENSG00000099337|Vega:OTTHUMG00000182325 +9425 CDYL MIM:603778|HGNC:HGNC:1811|Ensembl:ENSG00000153046|Vega:OTTHUMG00000014170 +9426 CDY2A MIM:400018|HGNC:HGNC:1810|Ensembl:ENSG00000182415|Vega:OTTHUMG00000041657 +9427 ECEL1 MIM:605896|HGNC:HGNC:3147|Ensembl:ENSG00000171551|Vega:OTTHUMG00000133262 +9429 ABCG2 MIM:603756|HGNC:HGNC:74|Ensembl:ENSG00000118777|Vega:OTTHUMG00000130601 +9430 MYLKP1 HGNC:HGNC:7591 +9431 OR7E22P HGNC:HGNC:8394 +9432 OR7E21P HGNC:HGNC:8393 +9435 CHST2 MIM:603798|HGNC:HGNC:1970|Ensembl:ENSG00000175040|Vega:OTTHUMG00000159351 +9436 NCR2 MIM:604531|HGNC:HGNC:6732|Ensembl:ENSG00000096264|Vega:OTTHUMG00000014678 +9437 NCR1 MIM:604530|HGNC:HGNC:6731|Ensembl:ENSG00000189430|Vega:OTTHUMG00000183212 +9439 MED23 MIM:605042|HGNC:HGNC:2372|Ensembl:ENSG00000112282|Vega:OTTHUMG00000015565 +9440 MED17 MIM:603810|HGNC:HGNC:2375|Ensembl:ENSG00000042429|Vega:OTTHUMG00000167497 +9441 MED26 MIM:605043|HGNC:HGNC:2376|Ensembl:ENSG00000105085|Vega:OTTHUMG00000182433 +9442 MED27 MIM:605044|HGNC:HGNC:2377|Ensembl:ENSG00000160563|Vega:OTTHUMG00000020833 +9443 MED7 MIM:605045|HGNC:HGNC:2378|Ensembl:ENSG00000155868|Vega:OTTHUMG00000130243 +9444 QKI MIM:609590|HGNC:HGNC:21100|Ensembl:ENSG00000112531|Vega:OTTHUMG00000015977 +9445 ITM2B MIM:603904|HGNC:HGNC:6174|Ensembl:ENSG00000136156|Vega:OTTHUMG00000016894 +9446 GSTO1 MIM:605482|HGNC:HGNC:13312|Ensembl:ENSG00000148834|Vega:OTTHUMG00000019001 +9447 AIM2 MIM:604578|HGNC:HGNC:357|Ensembl:ENSG00000163568|Vega:OTTHUMG00000037183 +9448 MAP4K4 MIM:604666|HGNC:HGNC:6866|Ensembl:ENSG00000071054|Vega:OTTHUMG00000155394 +9450 LY86 MIM:605241|HGNC:HGNC:16837|Ensembl:ENSG00000112799|Vega:OTTHUMG00000014190 +9451 EIF2AK3 MIM:604032|HGNC:HGNC:3255|Ensembl:ENSG00000172071|Vega:OTTHUMG00000155046 +9452 ITM2A MIM:300222|HGNC:HGNC:6173|Ensembl:ENSG00000078596|Vega:OTTHUMG00000021900 +9453 GGPS1 MIM:606982|HGNC:HGNC:4249|Ensembl:ENSG00000152904|Vega:OTTHUMG00000037963 +9454 HOMER3 MIM:604800|HGNC:HGNC:17514|Ensembl:ENSG00000051128|Vega:OTTHUMG00000182995 +9455 HOMER2 MIM:604799|HGNC:HGNC:17513|Ensembl:ENSG00000103942|Vega:OTTHUMG00000172462 +9456 HOMER1 MIM:604798|HGNC:HGNC:17512|Ensembl:ENSG00000152413|Vega:OTTHUMG00000134278 +9457 FHL5 MIM:605126|HGNC:HGNC:17371|Ensembl:ENSG00000112214|Vega:OTTHUMG00000015239 +9459 ARHGEF6 MIM:300267|HGNC:HGNC:685|Ensembl:ENSG00000129675|Vega:OTTHUMG00000022518 +9462 RASAL2 MIM:606136|HGNC:HGNC:9874|Ensembl:ENSG00000075391|Vega:OTTHUMG00000035022 +9463 PICK1 MIM:605926|HGNC:HGNC:9394|Ensembl:ENSG00000100151|Vega:OTTHUMG00000151159 +9464 HAND2 MIM:602407|HGNC:HGNC:4808|Ensembl:ENSG00000164107|Vega:OTTHUMG00000160775 +9465 AKAP7 MIM:604693|HGNC:HGNC:377|Ensembl:ENSG00000118507|Vega:OTTHUMG00000015563 +9466 IL27RA MIM:605350|HGNC:HGNC:17290|Ensembl:ENSG00000104998|Vega:OTTHUMG00000181990 +9467 SH3BP5 MIM:605612|HGNC:HGNC:10827|Ensembl:ENSG00000131370|Vega:OTTHUMG00000129859 +9468 PCYT1B MIM:300948|HGNC:HGNC:8755|Ensembl:ENSG00000102230|Vega:OTTHUMG00000021270 +9469 CHST3 MIM:603799|HGNC:HGNC:1971|Ensembl:ENSG00000122863|Vega:OTTHUMG00000018431 +9470 EIF4E2 MIM:605895|HGNC:HGNC:3293|Ensembl:ENSG00000135930|Vega:OTTHUMG00000133256 +9472 AKAP6 MIM:604691|HGNC:HGNC:376|Ensembl:ENSG00000151320|Vega:OTTHUMG00000140207 +9473 THEMIS2 HGNC:HGNC:16839|Ensembl:ENSG00000130775|Vega:OTTHUMG00000003735 +9474 ATG5 MIM:604261|HGNC:HGNC:589|Ensembl:ENSG00000057663|Vega:OTTHUMG00000016193 +9475 ROCK2 MIM:604002|HGNC:HGNC:10252|Ensembl:ENSG00000134318|Vega:OTTHUMG00000149916 +9476 NAPSA MIM:605631|HGNC:HGNC:13395|Ensembl:ENSG00000131400|Vega:OTTHUMG00000183035 +9477 MED20 MIM:612915|HGNC:HGNC:16840|Ensembl:ENSG00000124641|Vega:OTTHUMG00000014689 +9478 CABP1 MIM:605563|HGNC:HGNC:1384|Ensembl:ENSG00000157782|Vega:OTTHUMG00000156794 +9479 MAPK8IP1 MIM:604641|HGNC:HGNC:6882|Ensembl:ENSG00000121653|Vega:OTTHUMG00000134324 +9480 ONECUT2 MIM:604894|HGNC:HGNC:8139|Ensembl:ENSG00000119547|Vega:OTTHUMG00000159776 +9481 SLC25A27 MIM:613725|HGNC:HGNC:21065|Ensembl:ENSG00000153291|Vega:OTTHUMG00000014786 +9482 STX8 MIM:604203|HGNC:HGNC:11443|Ensembl:ENSG00000170310|Vega:OTTHUMG00000177844 +9486 CHST10 MIM:606376|HGNC:HGNC:19650|Ensembl:ENSG00000115526|Vega:OTTHUMG00000130669 +9487 PIGL MIM:605947|HGNC:HGNC:8966|Ensembl:ENSG00000108474|Vega:OTTHUMG00000059346 +9488 PIGB MIM:604122|HGNC:HGNC:8959|Ensembl:ENSG00000069943|Vega:OTTHUMG00000172654 +9489 PGS1 MIM:614942|HGNC:HGNC:30029|Ensembl:ENSG00000087157|Vega:OTTHUMG00000177514 +9491 PSMF1 HGNC:HGNC:9571|Ensembl:ENSG00000125818|Vega:OTTHUMG00000031656 +9493 KIF23 MIM:605064|HGNC:HGNC:6392|Ensembl:ENSG00000137807|Vega:OTTHUMG00000172062 +9495 AKAP5 MIM:604688|HGNC:HGNC:375|Ensembl:ENSG00000179841|Vega:OTTHUMG00000029634 +9496 TBX4 MIM:601719|HGNC:HGNC:11603|Ensembl:ENSG00000121075|Vega:OTTHUMG00000180078 +9497 SLC4A7 MIM:603353|HGNC:HGNC:11033|Ensembl:ENSG00000033867|Vega:OTTHUMG00000155679 +9498 SLC4A8 MIM:605024|HGNC:HGNC:11034|Ensembl:ENSG00000050438|Vega:OTTHUMG00000169489 +9499 MYOT MIM:604103|HGNC:HGNC:12399|Ensembl:ENSG00000120729|Vega:OTTHUMG00000129154 +9500 MAGED1 MIM:300224|HGNC:HGNC:6813|Ensembl:ENSG00000179222|Vega:OTTHUMG00000021540 +9501 RPH3AL MIM:604881|HGNC:HGNC:10296|Ensembl:ENSG00000181031|Vega:OTTHUMG00000090273 +9502 XAGE2 MIM:300416|HGNC:HGNC:4112|Ensembl:ENSG00000155622|Vega:OTTHUMG00000021549 +9506 PAGE4 MIM:300287|HGNC:HGNC:4108|Ensembl:ENSG00000101951|Vega:OTTHUMG00000024155 +9507 ADAMTS4 MIM:603876|HGNC:HGNC:220|Ensembl:ENSG00000158859|Vega:OTTHUMG00000034349 +9508 ADAMTS3 MIM:605011|HGNC:HGNC:219|Ensembl:ENSG00000156140|Vega:OTTHUMG00000129912 +9509 ADAMTS2 MIM:604539|HGNC:HGNC:218|Ensembl:ENSG00000087116|Vega:OTTHUMG00000130915 +9510 ADAMTS1 MIM:605174|HGNC:HGNC:217|Ensembl:ENSG00000154734|Vega:OTTHUMG00000078688 +9512 PMPCB MIM:603131|HGNC:HGNC:9119|Ensembl:ENSG00000105819|Vega:OTTHUMG00000157205 +9513 FXR2 MIM:605339|HGNC:HGNC:4024|Ensembl:ENSG00000129245|Vega:OTTHUMG00000178237 +9514 GAL3ST1 MIM:602300|HGNC:HGNC:24240|Ensembl:ENSG00000128242|Vega:OTTHUMG00000151200 +9515 STXBP5L MIM:609381|HGNC:HGNC:30757|Ensembl:ENSG00000145087|Vega:OTTHUMG00000159426 +9516 LITAF MIM:603795|HGNC:HGNC:16841|Ensembl:ENSG00000189067|Vega:OTTHUMG00000177415 +9517 SPTLC2 MIM:605713|HGNC:HGNC:11278|Ensembl:ENSG00000100596|Vega:OTTHUMG00000171540 +9518 GDF15 MIM:605312|HGNC:HGNC:30142|Ensembl:ENSG00000130513|Vega:OTTHUMG00000183360 +9519 TBPL1 MIM:605521|HGNC:HGNC:11589|Ensembl:ENSG00000028839|Vega:OTTHUMG00000015609 +9520 NPEPPS MIM:606793|HGNC:HGNC:7900|Ensembl:ENSG00000141279|Vega:OTTHUMG00000165471 +9521 EEF1E1 MIM:609206|HGNC:HGNC:3212|Ensembl:ENSG00000124802|Vega:OTTHUMG00000014221 +9522 SCAMP1 MIM:606911|HGNC:HGNC:10563|Ensembl:ENSG00000085365|Vega:OTTHUMG00000162479 +9524 TECR MIM:610057|HGNC:HGNC:4551|Ensembl:ENSG00000099797|Vega:OTTHUMG00000183290 +9525 VPS4B MIM:609983|HGNC:HGNC:10895|Ensembl:ENSG00000119541|Vega:OTTHUMG00000132790 +9526 MPDU1 MIM:604041|HGNC:HGNC:7207|Ensembl:ENSG00000129255|Vega:OTTHUMG00000108147 +9527 GOSR1 MIM:604026|HGNC:HGNC:4430|Ensembl:ENSG00000108587|Vega:OTTHUMG00000132796 +9528 TMEM59 MIM:617084|HGNC:HGNC:1239|Ensembl:ENSG00000116209|Vega:OTTHUMG00000008437 +9529 BAG5 MIM:603885|HGNC:HGNC:941|Ensembl:ENSG00000166170|Vega:OTTHUMG00000171763 +9530 BAG4 MIM:603884|HGNC:HGNC:940|Ensembl:ENSG00000156735|Vega:OTTHUMG00000164064 +9531 BAG3 MIM:603883|HGNC:HGNC:939|Ensembl:ENSG00000151929|Vega:OTTHUMG00000019155 +9532 BAG2 MIM:603882|HGNC:HGNC:938|Ensembl:ENSG00000112208|Vega:OTTHUMG00000014919 +9533 POLR1C MIM:610060|HGNC:HGNC:20194|Ensembl:ENSG00000171453|Vega:OTTHUMG00000014739 +9534 ZNF254 MIM:604768|HGNC:HGNC:13047|Ensembl:ENSG00000213096|Vega:OTTHUMG00000183394 +9535 GMFG MIM:604104|HGNC:HGNC:4374|Ensembl:ENSG00000130755|Vega:OTTHUMG00000182811 +9536 PTGES MIM:605172|HGNC:HGNC:9599|Ensembl:ENSG00000148344|Vega:OTTHUMG00000020791 +9537 TP53I11 HGNC:HGNC:16842|Ensembl:ENSG00000175274|Vega:OTTHUMG00000165714 +9538 EI24 MIM:605170|HGNC:HGNC:13276|Ensembl:ENSG00000149547|Vega:OTTHUMG00000165851 +9540 TP53I3 MIM:605171|HGNC:HGNC:19373|Ensembl:ENSG00000115129|Vega:OTTHUMG00000090817 +9541 CIR1 MIM:605228|HGNC:HGNC:24217|Ensembl:ENSG00000138433|Vega:OTTHUMG00000132338 +9542 NRG2 MIM:603818|HGNC:HGNC:7998|Ensembl:ENSG00000158458|Vega:OTTHUMG00000129241 +9543 IGDCC3 MIM:604184|HGNC:HGNC:9700|Ensembl:ENSG00000174498|Vega:OTTHUMG00000133137 +9545 RAB3D MIM:604350|HGNC:HGNC:9779|Ensembl:ENSG00000105514|Vega:OTTHUMG00000180835 +9546 APBA3 MIM:604262|HGNC:HGNC:580|Ensembl:ENSG00000011132|Vega:OTTHUMG00000180915 +9547 CXCL14 MIM:604186|HGNC:HGNC:10640|Ensembl:ENSG00000145824|Vega:OTTHUMG00000129139 +9550 ATP6V1G1 MIM:607296|HGNC:HGNC:864|Ensembl:ENSG00000136888|Vega:OTTHUMG00000021023 +9551 ATP5J2 HGNC:HGNC:848|Ensembl:ENSG00000241468|Vega:OTTHUMG00000154609 +9552 SPAG7 MIM:610056|HGNC:HGNC:11216|Ensembl:ENSG00000091640|Vega:OTTHUMG00000177733 +9553 MRPL33 MIM:610059|HGNC:HGNC:14487|Ensembl:ENSG00000243147|Vega:OTTHUMG00000097795 +9554 SEC22B MIM:604029|HGNC:HGNC:10700|Ensembl:ENSG00000265808|Vega:OTTHUMG00000185008 +9555 H2AFY MIM:610054|HGNC:HGNC:4740|Ensembl:ENSG00000113648|Vega:OTTHUMG00000129141 +9556 C14orf2 MIM:604573|HGNC:HGNC:1188|Ensembl:ENSG00000156411|Vega:OTTHUMG00000171601 +9557 CHD1L MIM:613039|HGNC:HGNC:1916|Ensembl:ENSG00000131778|Vega:OTTHUMG00000150271 +9559 VPS26A MIM:605506|HGNC:HGNC:12711|Ensembl:ENSG00000122958|Vega:OTTHUMG00000018376 +9560 CCL4L2 MIM:610757|HGNC:HGNC:24066|Ensembl:ENSG00000276070|Vega:OTTHUMG00000188420 +9562 MINPP1 MIM:605391|HGNC:HGNC:7102|Ensembl:ENSG00000107789|Vega:OTTHUMG00000018678 +9563 H6PD MIM:138090|HGNC:HGNC:4795|Ensembl:ENSG00000049239|Vega:OTTHUMG00000001768 +9564 BCAR1 MIM:602941|HGNC:HGNC:971|Ensembl:ENSG00000050820|Vega:OTTHUMG00000137604 +9566 HPCX MIM:300147|HGNC:HGNC:5146 +9567 GTPBP1 MIM:602245|HGNC:HGNC:4669|Ensembl:ENSG00000100226|Vega:OTTHUMG00000151002 +9568 GABBR2 MIM:607340|HGNC:HGNC:4507|Ensembl:ENSG00000136928|Vega:OTTHUMG00000020345 +9569 GTF2IRD1 MIM:604318|HGNC:HGNC:4661|Ensembl:ENSG00000006704|Vega:OTTHUMG00000023782 +9570 GOSR2 MIM:604027|HGNC:HGNC:4431|Ensembl:ENSG00000108433|Ensembl:ENSG00000262633|Vega:OTTHUMG00000178080|Vega:OTTHUMG00000178081 +9572 NR1D1 MIM:602408|HGNC:HGNC:7962|Ensembl:ENSG00000126368|Vega:OTTHUMG00000133327 +9573 GDF3 MIM:606522|HGNC:HGNC:4218|Ensembl:ENSG00000184344|Vega:OTTHUMG00000168433 +9575 CLOCK MIM:601851|HGNC:HGNC:2082|Ensembl:ENSG00000134852|Vega:OTTHUMG00000102141 +9576 SPAG6 MIM:605730|HGNC:HGNC:11215|Ensembl:ENSG00000077327|Vega:OTTHUMG00000017808 +9577 BABAM2 MIM:610497|HGNC:HGNC:1106|Ensembl:ENSG00000158019|Vega:OTTHUMG00000097831 +9578 CDC42BPB MIM:614062|HGNC:HGNC:1738|Ensembl:ENSG00000198752|Vega:OTTHUMG00000171898 +9580 SOX13 MIM:604748|HGNC:HGNC:11192|Ensembl:ENSG00000143842|Vega:OTTHUMG00000036050 +9581 PREPL MIM:609557|HGNC:HGNC:30228|Ensembl:ENSG00000138078|Vega:OTTHUMG00000152791 +9582 APOBEC3B MIM:607110|HGNC:HGNC:17352|Ensembl:ENSG00000179750|Vega:OTTHUMG00000151085 +9583 ENTPD4 MIM:607577|HGNC:HGNC:14573|Ensembl:ENSG00000197217|Vega:OTTHUMG00000097852 +9584 RBM39 MIM:604739|HGNC:HGNC:15923|Ensembl:ENSG00000131051|Vega:OTTHUMG00000032358 +9585 KIF20B MIM:605498|HGNC:HGNC:7212|Ensembl:ENSG00000138182|Vega:OTTHUMG00000018725 +9586 CREB5 HGNC:HGNC:16844|Ensembl:ENSG00000146592|Vega:OTTHUMG00000097081 +9587 MAD2L1BP HGNC:HGNC:21059|Ensembl:ENSG00000124688|Vega:OTTHUMG00000014747 +9588 PRDX6 MIM:602316|HGNC:HGNC:16753|Ensembl:ENSG00000117592|Vega:OTTHUMG00000034804 +9589 WTAP MIM:605442|HGNC:HGNC:16846|Ensembl:ENSG00000146457|Vega:OTTHUMG00000015933 +9590 AKAP12 MIM:604698|HGNC:HGNC:370|Ensembl:ENSG00000131016|Vega:OTTHUMG00000015833 +9592 IER2 HGNC:HGNC:28871|Ensembl:ENSG00000160888|Vega:OTTHUMG00000180790 +9595 CYTIP MIM:604448|HGNC:HGNC:9506|Ensembl:ENSG00000115165|Vega:OTTHUMG00000154551 +9596 OR1R1P HGNC:HGNC:8226 +9597 SMAD5-AS1 HGNC:HGNC:30586|Ensembl:ENSG00000164621 +9600 PITPNM1 MIM:608794|HGNC:HGNC:9003|Ensembl:ENSG00000110697|Vega:OTTHUMG00000167675 +9601 PDIA4 HGNC:HGNC:30167|Ensembl:ENSG00000155660|Vega:OTTHUMG00000150248 +9603 NFE2L3 MIM:604135|HGNC:HGNC:7783|Ensembl:ENSG00000050344|Vega:OTTHUMG00000023882 +9604 RNF14 MIM:605675|HGNC:HGNC:10058|Ensembl:ENSG00000013561|Vega:OTTHUMG00000129660 +9605 VPS9D1 HGNC:HGNC:13526|Ensembl:ENSG00000075399|Vega:OTTHUMG00000173219 +9607 CARTPT MIM:602606|HGNC:HGNC:24323|Ensembl:ENSG00000164326|Vega:OTTHUMG00000131261 +9609 RAB36 MIM:605662|HGNC:HGNC:9775|Ensembl:ENSG00000100228|Vega:OTTHUMG00000150601 +9610 RIN1 MIM:605965|HGNC:HGNC:18749|Ensembl:ENSG00000174791|Vega:OTTHUMG00000167085 +9611 NCOR1 MIM:600849|HGNC:HGNC:7672|Ensembl:ENSG00000141027|Vega:OTTHUMG00000059309 +9612 NCOR2 MIM:600848|HGNC:HGNC:7673|Ensembl:ENSG00000196498|Vega:OTTHUMG00000150455 +9615 GDA MIM:139260|HGNC:HGNC:4212|Ensembl:ENSG00000119125|Vega:OTTHUMG00000020005 +9616 RNF7 MIM:603863|HGNC:HGNC:10070|Ensembl:ENSG00000114125|Vega:OTTHUMG00000141305 +9617 MTRF1 MIM:604601|HGNC:HGNC:7469|Ensembl:ENSG00000120662|Vega:OTTHUMG00000016790 +9618 TRAF4 MIM:602464|HGNC:HGNC:12034|Ensembl:ENSG00000076604|Vega:OTTHUMG00000132677 +9619 ABCG1 MIM:603076|HGNC:HGNC:73|Ensembl:ENSG00000160179|Vega:OTTHUMG00000086791 +9620 CELSR1 MIM:604523|HGNC:HGNC:1850|Ensembl:ENSG00000075275|Vega:OTTHUMG00000150423 +9622 KLK4 MIM:603767|HGNC:HGNC:6365|Ensembl:ENSG00000167749|Vega:OTTHUMG00000182964 +9623 TCL1B MIM:603769|HGNC:HGNC:11649|Ensembl:ENSG00000213231|Vega:OTTHUMG00000028912 +9625 AATK MIM:605276|HGNC:HGNC:21|Ensembl:ENSG00000181409|Vega:OTTHUMG00000132717 +9626 GUCA1C MIM:605128|HGNC:HGNC:4680|Ensembl:ENSG00000138472|Vega:OTTHUMG00000159204 +9627 SNCAIP MIM:603779|HGNC:HGNC:11139|Ensembl:ENSG00000064692|Vega:OTTHUMG00000128915 +9628 RGS6 MIM:603894|HGNC:HGNC:10002|Ensembl:ENSG00000182732|Vega:OTTHUMG00000171340 +9629 CLCA3P MIM:604337|HGNC:HGNC:2017|Ensembl:ENSG00000153923 +9630 GNA14 MIM:604397|HGNC:HGNC:4382|Ensembl:ENSG00000156049|Vega:OTTHUMG00000020058 +9631 NUP155 MIM:606694|HGNC:HGNC:8063|Ensembl:ENSG00000113569|Vega:OTTHUMG00000090803 +9632 SEC24C MIM:607185|HGNC:HGNC:10705|Ensembl:ENSG00000176986|Vega:OTTHUMG00000018476 +9633 TESMIN MIM:604374|HGNC:HGNC:7446|Ensembl:ENSG00000132749|Vega:OTTHUMG00000167891 +9635 CLCA2 MIM:604003|HGNC:HGNC:2016|Ensembl:ENSG00000137975|Vega:OTTHUMG00000010256 +9636 ISG15 MIM:147571|HGNC:HGNC:4053|Ensembl:ENSG00000187608|Vega:OTTHUMG00000040777 +9637 FEZ2 MIM:604826|HGNC:HGNC:3660|Ensembl:ENSG00000171055|Vega:OTTHUMG00000152148 +9638 FEZ1 MIM:604825|HGNC:HGNC:3659|Ensembl:ENSG00000149557|Vega:OTTHUMG00000165886 +9639 ARHGEF10 MIM:608136|HGNC:HGNC:14103|Ensembl:ENSG00000104728|Vega:OTTHUMG00000163626 +9640 ZNF592 MIM:613624|HGNC:HGNC:28986|Ensembl:ENSG00000166716|Vega:OTTHUMG00000172490 +9641 IKBKE MIM:605048|HGNC:HGNC:14552|Ensembl:ENSG00000263528|Vega:OTTHUMG00000184613 +9643 MORF4L2 MIM:300409|HGNC:HGNC:16849|Ensembl:ENSG00000123562|Vega:OTTHUMG00000022104 +9644 SH3PXD2A HGNC:HGNC:23664|Ensembl:ENSG00000107957|Vega:OTTHUMG00000018997 +9645 MICAL2 MIM:608881|HGNC:HGNC:24693|Ensembl:ENSG00000133816|Vega:OTTHUMG00000165744 +9646 CTR9 MIM:609366|HGNC:HGNC:16850|Ensembl:ENSG00000198730|Vega:OTTHUMG00000165789 +9647 PPM1F HGNC:HGNC:19388|Ensembl:ENSG00000100034|Vega:OTTHUMG00000150835 +9648 GCC2 MIM:612711|HGNC:HGNC:23218|Ensembl:ENSG00000135968|Vega:OTTHUMG00000153214 +9649 RALGPS1 MIM:614444|HGNC:HGNC:16851|Ensembl:ENSG00000136828|Vega:OTTHUMG00000020696 +9650 MTFR1 HGNC:HGNC:29510|Ensembl:ENSG00000066855|Vega:OTTHUMG00000164468 +9651 PLCH2 MIM:612836|HGNC:HGNC:29037|Ensembl:ENSG00000149527|Vega:OTTHUMG00000000719 +9652 TTC37 MIM:614589|HGNC:HGNC:23639|Ensembl:ENSG00000198677|Vega:OTTHUMG00000121165 +9653 HS2ST1 MIM:604844|HGNC:HGNC:5193|Ensembl:ENSG00000153936|Vega:OTTHUMG00000010255 +9654 TTLL4 HGNC:HGNC:28976|Ensembl:ENSG00000135912|Vega:OTTHUMG00000133081 +9655 SOCS5 MIM:607094|HGNC:HGNC:16852|Ensembl:ENSG00000171150|Vega:OTTHUMG00000128852 +9656 MDC1 MIM:607593|HGNC:HGNC:21163|Ensembl:ENSG00000137337|Vega:OTTHUMG00000031075 +9657 IQCB1 MIM:609237|HGNC:HGNC:28949|Ensembl:ENSG00000173226|Vega:OTTHUMG00000128677 +9658 ZNF516 MIM:615114|HGNC:HGNC:28990|Ensembl:ENSG00000101493|Vega:OTTHUMG00000165995 +9659 PDE4DIP MIM:608117|HGNC:HGNC:15580|Ensembl:ENSG00000178104|Vega:OTTHUMG00000013846 +9662 CEP135 MIM:611423|HGNC:HGNC:29086|Ensembl:ENSG00000174799|Vega:OTTHUMG00000160748 +9663 LPIN2 MIM:605519|HGNC:HGNC:14450|Ensembl:ENSG00000101577|Vega:OTTHUMG00000131508 +9665 MARF1 MIM:614593|HGNC:HGNC:29562|Ensembl:ENSG00000166783|Vega:OTTHUMG00000129884 +9666 DZIP3 MIM:608672|HGNC:HGNC:30938|Ensembl:ENSG00000198919|Vega:OTTHUMG00000159232 +9667 SAFB2 MIM:608066|HGNC:HGNC:21605|Ensembl:ENSG00000130254|Vega:OTTHUMG00000180374 +9668 ZNF432 HGNC:HGNC:20810|Ensembl:ENSG00000256087|Vega:OTTHUMG00000182552 +9669 EIF5B MIM:606086|HGNC:HGNC:30793|Ensembl:ENSG00000158417|Vega:OTTHUMG00000153242 +9670 IPO13 MIM:610411|HGNC:HGNC:16853|Ensembl:ENSG00000117408|Vega:OTTHUMG00000008297 +9671 WSCD2 HGNC:HGNC:29117|Ensembl:ENSG00000075035|Vega:OTTHUMG00000169579 +9672 SDC3 MIM:186357|HGNC:HGNC:10660|Ensembl:ENSG00000162512|Vega:OTTHUMG00000043646 +9673 SLC25A44 MIM:610824|HGNC:HGNC:29036|Ensembl:ENSG00000160785|Vega:OTTHUMG00000014816 +9674 KIAA0040 MIM:616696|HGNC:HGNC:28950|Ensembl:ENSG00000235750|Vega:OTTHUMG00000034880 +9675 TTI1 MIM:614425|HGNC:HGNC:29029|Ensembl:ENSG00000101407|Vega:OTTHUMG00000032433 +9677 PPIP5K1 MIM:610979|HGNC:HGNC:29023|Ensembl:ENSG00000168781|Vega:OTTHUMG00000059758 +9678 PHF14 HGNC:HGNC:22203|Ensembl:ENSG00000106443|Vega:OTTHUMG00000150463 +9679 FAM53B MIM:617289|HGNC:HGNC:28968|Ensembl:ENSG00000189319|Vega:OTTHUMG00000019215 +9681 DEPDC5 MIM:614191|HGNC:HGNC:18423|Ensembl:ENSG00000100150|Vega:OTTHUMG00000030926 +9682 KDM4A MIM:609764|HGNC:HGNC:22978|Ensembl:ENSG00000066135|Vega:OTTHUMG00000007560 +9683 N4BP1 HGNC:HGNC:29850|Ensembl:ENSG00000102921|Vega:OTTHUMG00000175421 +9684 LRRC14 HGNC:HGNC:20419|Ensembl:ENSG00000160959|Vega:OTTHUMG00000165179 +9685 CLINT1 MIM:607265|HGNC:HGNC:23186|Ensembl:ENSG00000113282|Vega:OTTHUMG00000163527 +9686 VGLL4 HGNC:HGNC:28966|Ensembl:ENSG00000144560|Vega:OTTHUMG00000129739 +9687 GREB1 MIM:611736|HGNC:HGNC:24885|Ensembl:ENSG00000196208|Vega:OTTHUMG00000141276 +9688 NUP93 MIM:614351|HGNC:HGNC:28958|Ensembl:ENSG00000102900|Vega:OTTHUMG00000133278 +9689 BZW1 HGNC:HGNC:18380|Ensembl:ENSG00000082153|Vega:OTTHUMG00000154560 +9690 UBE3C MIM:614454|HGNC:HGNC:16803|Ensembl:ENSG00000009335|Vega:OTTHUMG00000157239 +9692 KIAA0391 MIM:609947|HGNC:HGNC:19958|Ensembl:ENSG00000100890|Ensembl:ENSG00000258790|Vega:OTTHUMG00000170997|Vega:OTTHUMG00000171025 +9693 RAPGEF2 MIM:609530|HGNC:HGNC:16854|Ensembl:ENSG00000109756|Vega:OTTHUMG00000161451 +9694 EMC2 MIM:607722|HGNC:HGNC:28963|Ensembl:ENSG00000104412|Vega:OTTHUMG00000164873 +9695 EDEM1 MIM:607673|HGNC:HGNC:18967|Ensembl:ENSG00000134109|Vega:OTTHUMG00000154896 +9696 CROCC MIM:615776|HGNC:HGNC:21299|Ensembl:ENSG00000058453|Vega:OTTHUMG00000002200 +9697 TRAM2 MIM:608485|HGNC:HGNC:16855|Ensembl:ENSG00000065308|Vega:OTTHUMG00000014850 +9698 PUM1 MIM:607204|HGNC:HGNC:14957|Ensembl:ENSG00000134644|Vega:OTTHUMG00000003795 +9699 RIMS2 MIM:606630|HGNC:HGNC:17283|Ensembl:ENSG00000176406|Vega:OTTHUMG00000162097 +9700 ESPL1 MIM:604143|HGNC:HGNC:16856|Ensembl:ENSG00000135476|Vega:OTTHUMG00000169674 +9701 PPP6R2 MIM:610877|HGNC:HGNC:19253|Ensembl:ENSG00000100239|Vega:OTTHUMG00000150199 +9702 CEP57 MIM:607951|HGNC:HGNC:30794|Ensembl:ENSG00000166037|Vega:OTTHUMG00000167740 +9703 KIAA0100 MIM:610664|HGNC:HGNC:28960|Ensembl:ENSG00000007202|Vega:OTTHUMG00000166587 +9704 DHX34 MIM:615475|HGNC:HGNC:16719|Ensembl:ENSG00000134815|Vega:OTTHUMG00000149959 +9705 ST18 MIM:617155|HGNC:HGNC:18695|Ensembl:ENSG00000147488|Vega:OTTHUMG00000164233 +9706 ULK2 MIM:608650|HGNC:HGNC:13480|Ensembl:ENSG00000083290|Vega:OTTHUMG00000059511 +9708 PCDHGA8 MIM:606295|HGNC:HGNC:8706|Ensembl:ENSG00000253767|Vega:OTTHUMG00000164053 +9709 HERPUD1 MIM:608070|HGNC:HGNC:13744|Ensembl:ENSG00000051108|Vega:OTTHUMG00000133276 +9710 KIAA0355 HGNC:HGNC:29016|Ensembl:ENSG00000166398|Vega:OTTHUMG00000180505 +9711 RUBCN MIM:613516|HGNC:HGNC:28991|Ensembl:ENSG00000145016|Vega:OTTHUMG00000155452 +9712 USP6NL MIM:605405|HGNC:HGNC:16858|Ensembl:ENSG00000148429|Vega:OTTHUMG00000017672 +9715 FAM131B HGNC:HGNC:22202|Ensembl:ENSG00000159784|Vega:OTTHUMG00000152697 +9716 AQR MIM:610548|HGNC:HGNC:29513|Ensembl:ENSG00000021776|Vega:OTTHUMG00000172257 +9717 SEC14L5 HGNC:HGNC:29032|Ensembl:ENSG00000103184|Vega:OTTHUMG00000176942 +9718 ECE2 MIM:610145|HGNC:HGNC:13275|Ensembl:ENSG00000145194|Vega:OTTHUMG00000150551 +9719 ADAMTSL2 MIM:612277|HGNC:HGNC:14631|Ensembl:ENSG00000197859|Vega:OTTHUMG00000131706 +9720 CCDC144A HGNC:HGNC:29072|Ensembl:ENSG00000170160|Ensembl:ENSG00000266302|Vega:OTTHUMG00000059178|Vega:OTTHUMG00000179236 +9721 GPRIN2 MIM:611240|HGNC:HGNC:23730|Ensembl:ENSG00000204175|Vega:OTTHUMG00000018107 +9722 NOS1AP MIM:605551|HGNC:HGNC:16859|Ensembl:ENSG00000198929|Vega:OTTHUMG00000024049 +9723 SEMA3E MIM:608166|HGNC:HGNC:10727|Ensembl:ENSG00000170381|Vega:OTTHUMG00000154693 +9724 UTP14C MIM:608969|HGNC:HGNC:20321|Ensembl:ENSG00000253797|Vega:OTTHUMG00000164353 +9725 TMEM63A HGNC:HGNC:29118|Ensembl:ENSG00000196187|Vega:OTTHUMG00000037442 +9726 ZNF646 HGNC:HGNC:29004|Ensembl:ENSG00000167395|Vega:OTTHUMG00000047355 +9727 RAB11FIP3 MIM:608738|HGNC:HGNC:17224|Ensembl:ENSG00000090565|Vega:OTTHUMG00000047843 +9728 SECISBP2L MIM:615756|HGNC:HGNC:28997|Ensembl:ENSG00000138593|Vega:OTTHUMG00000172194 +9729 KIAA0408 HGNC:HGNC:21636|Ensembl:ENSG00000189367|Vega:OTTHUMG00000166439 +9730 DCAF1 MIM:617259|HGNC:HGNC:30911|Ensembl:ENSG00000145041|Vega:OTTHUMG00000156895 +9731 CEP104 MIM:616690|HGNC:HGNC:24866|Ensembl:ENSG00000116198|Vega:OTTHUMG00000003507 +9732 DOCK4 MIM:607679|HGNC:HGNC:19192|Ensembl:ENSG00000128512|Vega:OTTHUMG00000155077 +9733 SART3 MIM:611684|HGNC:HGNC:16860|Ensembl:ENSG00000075856|Vega:OTTHUMG00000169449 +9734 HDAC9 MIM:606543|HGNC:HGNC:14065|Ensembl:ENSG00000048052|Vega:OTTHUMG00000152487 +9735 KNTC1 MIM:607363|HGNC:HGNC:17255|Ensembl:ENSG00000184445|Vega:OTTHUMG00000168861 +9736 USP34 MIM:615295|HGNC:HGNC:20066|Ensembl:ENSG00000115464|Vega:OTTHUMG00000152265 +9737 GPRASP1 MIM:300417|HGNC:HGNC:24834|Ensembl:ENSG00000198932|Vega:OTTHUMG00000022061 +9738 CCP110 MIM:609544|HGNC:HGNC:24342|Ensembl:ENSG00000103540|Vega:OTTHUMG00000131459 +9739 SETD1A MIM:611052|HGNC:HGNC:29010|Ensembl:ENSG00000099381|Vega:OTTHUMG00000150474 +9741 LAPTM4A HGNC:HGNC:6924|Ensembl:ENSG00000068697|Vega:OTTHUMG00000090750 +9742 IFT140 MIM:614620|HGNC:HGNC:29077|Ensembl:ENSG00000187535|Vega:OTTHUMG00000128585 +9743 ARHGAP32 MIM:608541|HGNC:HGNC:17399|Ensembl:ENSG00000134909|Vega:OTTHUMG00000165774 +9744 ACAP1 MIM:607763|HGNC:HGNC:16467|Ensembl:ENSG00000072818|Vega:OTTHUMG00000102199 +9745 ZNF536 HGNC:HGNC:29025|Ensembl:ENSG00000198597|Vega:OTTHUMG00000182112 +9746 CLSTN3 MIM:611324|HGNC:HGNC:18371|Ensembl:ENSG00000139182|Vega:OTTHUMG00000168167 +9747 TCAF1 MIM:616251|HGNC:HGNC:22201|Ensembl:ENSG00000198420|Vega:OTTHUMG00000157773 +9748 SLK MIM:616563|HGNC:HGNC:11088|Ensembl:ENSG00000065613|Vega:OTTHUMG00000018999 +9749 PHACTR2 MIM:608724|HGNC:HGNC:20956|Ensembl:ENSG00000112419|Vega:OTTHUMG00000015732 +9750 RIPOR2 MIM:611410|HGNC:HGNC:13872|Ensembl:ENSG00000111913|Vega:OTTHUMG00000191459 +9751 SNPH MIM:604942|HGNC:HGNC:15931|Ensembl:ENSG00000101298|Vega:OTTHUMG00000031662 +9752 PCDHA9 MIM:606315|HGNC:HGNC:8675|Ensembl:ENSG00000204961|Vega:OTTHUMG00000163373 +9753 ZSCAN12 MIM:603978|HGNC:HGNC:13172|Ensembl:ENSG00000158691|Vega:OTTHUMG00000014522 +9754 STARD8 MIM:300689|HGNC:HGNC:19161|Ensembl:ENSG00000130052|Vega:OTTHUMG00000021748 +9755 TBKBP1 MIM:608476|HGNC:HGNC:30140|Ensembl:ENSG00000198933|Vega:OTTHUMG00000178286 +9757 KMT2B MIM:606834|HGNC:HGNC:15840|Ensembl:ENSG00000272333|Vega:OTTHUMG00000048119 +9758 FRMPD4 MIM:300838|HGNC:HGNC:29007|Ensembl:ENSG00000169933|Vega:OTTHUMG00000021138 +9759 HDAC4 MIM:605314|HGNC:HGNC:14063|Ensembl:ENSG00000068024|Vega:OTTHUMG00000133344 +9760 TOX MIM:606863|HGNC:HGNC:18988|Ensembl:ENSG00000198846|Vega:OTTHUMG00000164331 +9761 MLEC MIM:613802|HGNC:HGNC:28973|Ensembl:ENSG00000110917|Vega:OTTHUMG00000169187 +9762 LZTS3 MIM:610484|HGNC:HGNC:30139|Ensembl:ENSG00000088899|Vega:OTTHUMG00000031735 +9764 KIAA0513 MIM:611675|HGNC:HGNC:29058|Ensembl:ENSG00000135709|Vega:OTTHUMG00000176597 +9765 ZFYVE16 MIM:608880|HGNC:HGNC:20756|Ensembl:ENSG00000039319|Vega:OTTHUMG00000108178 +9766 SUSD6 MIM:616761|HGNC:HGNC:19956|Ensembl:ENSG00000100647|Vega:OTTHUMG00000171234 +9767 JADE3 MIM:300618|HGNC:HGNC:22982|Ensembl:ENSG00000102221|Vega:OTTHUMG00000021431 +9768 PCLAF MIM:610696|HGNC:HGNC:28961|Ensembl:ENSG00000166803|Ensembl:ENSG00000259316|Vega:OTTHUMG00000133017|Vega:OTTHUMG00000172470 +9770 RASSF2 MIM:609492|HGNC:HGNC:9883|Ensembl:ENSG00000101265|Vega:OTTHUMG00000031790 +9771 RAPGEF5 MIM:609527|HGNC:HGNC:16862|Ensembl:ENSG00000136237|Vega:OTTHUMG00000152525 +9772 TMEM94 HGNC:HGNC:28983|Ensembl:ENSG00000177728|Vega:OTTHUMG00000179611 +9774 BCLAF1 MIM:612588|HGNC:HGNC:16863|Ensembl:ENSG00000029363|Vega:OTTHUMG00000033323 +9775 EIF4A3 MIM:608546|HGNC:HGNC:18683|Ensembl:ENSG00000141543|Vega:OTTHUMG00000177538 +9776 ATG13 MIM:615088|HGNC:HGNC:29091|Ensembl:ENSG00000175224|Vega:OTTHUMG00000166538 +9777 TM9SF4 HGNC:HGNC:30797|Ensembl:ENSG00000101337|Vega:OTTHUMG00000032206 +9778 KIAA0232 HGNC:HGNC:28992|Ensembl:ENSG00000170871|Vega:OTTHUMG00000160072 +9779 TBC1D5 MIM:615740|HGNC:HGNC:19166|Ensembl:ENSG00000131374|Vega:OTTHUMG00000155488 +9780 PIEZO1 MIM:611184|HGNC:HGNC:28993|Ensembl:ENSG00000103335|Vega:OTTHUMG00000156776 +9781 RNF144A HGNC:HGNC:20457|Ensembl:ENSG00000151692|Vega:OTTHUMG00000090353 +9782 MATR3 MIM:164015|HGNC:HGNC:6912|Ensembl:ENSG00000015479|Ensembl:ENSG00000280987|Vega:OTTHUMG00000129229|Vega:OTTHUMG00000189583 +9783 RIMS3 MIM:611600|HGNC:HGNC:21292|Ensembl:ENSG00000117016|Vega:OTTHUMG00000007453 +9784 SNX17 MIM:605963|HGNC:HGNC:14979|Ensembl:ENSG00000115234|Vega:OTTHUMG00000097781 +9785 DHX38 MIM:605584|HGNC:HGNC:17211|Ensembl:ENSG00000140829|Vega:OTTHUMG00000137596 +9786 KIAA0586 MIM:610178|HGNC:HGNC:19960|Ensembl:ENSG00000100578|Vega:OTTHUMG00000171141 +9787 DLGAP5 HGNC:HGNC:16864|Ensembl:ENSG00000126787|Vega:OTTHUMG00000140310 +9788 MTSS1 MIM:608486|HGNC:HGNC:20443|Ensembl:ENSG00000170873|Vega:OTTHUMG00000048189 +9789 SPCS2 HGNC:HGNC:28962|Ensembl:ENSG00000118363|Vega:OTTHUMG00000165517 +9790 BMS1 MIM:611448|HGNC:HGNC:23505|Ensembl:ENSG00000165733|Vega:OTTHUMG00000018020 +9791 PTDSS1 MIM:612792|HGNC:HGNC:9587|Ensembl:ENSG00000156471|Vega:OTTHUMG00000164687 +9792 SERTAD2 HGNC:HGNC:30784|Ensembl:ENSG00000179833|Vega:OTTHUMG00000152678 +9793 CKAP5 MIM:611142|HGNC:HGNC:28959|Ensembl:ENSG00000175216|Vega:OTTHUMG00000166599 +9794 MAML1 MIM:605424|HGNC:HGNC:13632|Ensembl:ENSG00000161021|Vega:OTTHUMG00000163237 +9796 PHYHIP MIM:608511|HGNC:HGNC:16865|Ensembl:ENSG00000168490|Vega:OTTHUMG00000163776 +9797 TATDN2 HGNC:HGNC:28988|Ensembl:ENSG00000157014|Ensembl:ENSG00000272410|Vega:OTTHUMG00000155361|Vega:OTTHUMG00000185357 +9798 IST1 MIM:616434|HGNC:HGNC:28977|Ensembl:ENSG00000182149|Vega:OTTHUMG00000137597 +9801 MRPL19 MIM:611832|HGNC:HGNC:14052|Ensembl:ENSG00000115364|Vega:OTTHUMG00000129990 +9802 DAZAP2 MIM:607431|HGNC:HGNC:2684|Ensembl:ENSG00000183283|Vega:OTTHUMG00000169649 +9804 TOMM20 MIM:601848|HGNC:HGNC:20947|Ensembl:ENSG00000173726|Vega:OTTHUMG00000039619 +9805 SCRN1 MIM:614965|HGNC:HGNC:22192|Ensembl:ENSG00000136193|Vega:OTTHUMG00000097093 +9806 SPOCK2 MIM:607988|HGNC:HGNC:13564|Ensembl:ENSG00000107742|Vega:OTTHUMG00000018430 +9807 IP6K1 MIM:606991|HGNC:HGNC:18360|Ensembl:ENSG00000176095|Vega:OTTHUMG00000158197 +9808 KIAA0087 HGNC:HGNC:22191|Ensembl:ENSG00000122548 +9810 RNF40 MIM:607700|HGNC:HGNC:16867|Ensembl:ENSG00000103549|Vega:OTTHUMG00000132394 +9811 CTIF MIM:613178|HGNC:HGNC:23925|Ensembl:ENSG00000134030|Vega:OTTHUMG00000132656 +9812 KIAA0141 MIM:615741|HGNC:HGNC:28969|Ensembl:ENSG00000081791|Vega:OTTHUMG00000129662 +9813 EFCAB14 HGNC:HGNC:29051|Ensembl:ENSG00000159658|Vega:OTTHUMG00000007992 +9814 SFI1 MIM:612765|HGNC:HGNC:29064|Ensembl:ENSG00000198089|Vega:OTTHUMG00000030249 +9815 GIT2 MIM:608564|HGNC:HGNC:4273|Ensembl:ENSG00000139436|Vega:OTTHUMG00000169313 +9816 URB2 HGNC:HGNC:28967|Ensembl:ENSG00000135763|Vega:OTTHUMG00000039464 +9817 KEAP1 MIM:606016|HGNC:HGNC:23177|Ensembl:ENSG00000079999|Vega:OTTHUMG00000180579 +9818 NUP58 MIM:607615|HGNC:HGNC:20261|Ensembl:ENSG00000139496|Vega:OTTHUMG00000016608 +9819 TSC22D2 HGNC:HGNC:29095|Ensembl:ENSG00000196428|Vega:OTTHUMG00000159744 +9820 CUL7 MIM:609577|HGNC:HGNC:21024|Ensembl:ENSG00000044090|Vega:OTTHUMG00000014718 +9821 RB1CC1 MIM:606837|HGNC:HGNC:15574|Ensembl:ENSG00000023287|Vega:OTTHUMG00000164268 +9823 ARMCX2 MIM:300363|HGNC:HGNC:16869|Ensembl:ENSG00000184867|Vega:OTTHUMG00000022038 +9824 ARHGAP11A MIM:610589|HGNC:HGNC:15783|Ensembl:ENSG00000198826|Vega:OTTHUMG00000129289 +9825 SPATA2 MIM:607662|HGNC:HGNC:14681|Ensembl:ENSG00000158480|Vega:OTTHUMG00000032704 +9826 ARHGEF11 MIM:605708|HGNC:HGNC:14580|Ensembl:ENSG00000132694|Vega:OTTHUMG00000041292 +9827 RGP1 MIM:615742|HGNC:HGNC:21965|Ensembl:ENSG00000107185|Vega:OTTHUMG00000019873 +9828 ARHGEF17 MIM:617043|HGNC:HGNC:21726|Ensembl:ENSG00000110237|Vega:OTTHUMG00000167971 +9829 DNAJC6 MIM:608375|HGNC:HGNC:15469|Ensembl:ENSG00000116675|Vega:OTTHUMG00000009066 +9830 TRIM14 MIM:606556|HGNC:HGNC:16283|Ensembl:ENSG00000106785|Vega:OTTHUMG00000020339 +9831 ZNF623 HGNC:HGNC:29084|Ensembl:ENSG00000183309|Vega:OTTHUMG00000165186 +9832 JAKMIP2 MIM:611197|HGNC:HGNC:29067|Ensembl:ENSG00000176049|Vega:OTTHUMG00000129731 +9833 MELK MIM:607025|HGNC:HGNC:16870|Ensembl:ENSG00000165304|Vega:OTTHUMG00000019906 +9834 FAM30A MIM:616623|HGNC:HGNC:19955|Ensembl:ENSG00000226777 +9836 LCMT2 MIM:611246|HGNC:HGNC:17558|Ensembl:ENSG00000168806|Vega:OTTHUMG00000130705 +9837 GINS1 MIM:610608|HGNC:HGNC:28980|Ensembl:ENSG00000101003|Vega:OTTHUMG00000032124 +9839 ZEB2 MIM:605802|HGNC:HGNC:14881|Ensembl:ENSG00000169554|Vega:OTTHUMG00000187624 +9840 TESPA1 MIM:615664|HGNC:HGNC:29109|Ensembl:ENSG00000135426|Vega:OTTHUMG00000165407 +9841 ZBTB24 MIM:614064|HGNC:HGNC:21143|Ensembl:ENSG00000112365|Vega:OTTHUMG00000015349 +9842 PLEKHM1 MIM:611466|HGNC:HGNC:29017|Ensembl:ENSG00000225190|Vega:OTTHUMG00000179074 +9843 HEPH MIM:300167|HGNC:HGNC:4866|Ensembl:ENSG00000089472|Vega:OTTHUMG00000021732 +9844 ELMO1 MIM:606420|HGNC:HGNC:16286|Ensembl:ENSG00000155849|Vega:OTTHUMG00000023701 +9846 GAB2 MIM:606203|HGNC:HGNC:14458|Ensembl:ENSG00000033327|Vega:OTTHUMG00000166673 +9847 C2CD5 HGNC:HGNC:29062|Ensembl:ENSG00000111731|Vega:OTTHUMG00000169100 +9848 MFAP3L MIM:616523|HGNC:HGNC:29083|Ensembl:ENSG00000198948|Vega:OTTHUMG00000160942 +9849 ZNF518A HGNC:HGNC:29009|Ensembl:ENSG00000177853|Vega:OTTHUMG00000018828 +9851 KIAA0753 MIM:617112|HGNC:HGNC:29110|Ensembl:ENSG00000198920|Vega:OTTHUMG00000177928 +9852 EPM2AIP1 MIM:607911|HGNC:HGNC:19735|Ensembl:ENSG00000178567|Vega:OTTHUMG00000185486 +9853 RUSC2 MIM:611053|HGNC:HGNC:23625|Ensembl:ENSG00000198853|Vega:OTTHUMG00000019861 +9854 C2CD2L HGNC:HGNC:29000|Ensembl:ENSG00000172375|Vega:OTTHUMG00000166167 +9855 FARP2 HGNC:HGNC:16460|Ensembl:ENSG00000006607|Vega:OTTHUMG00000151574 +9856 KIAA0319 MIM:609269|HGNC:HGNC:21580|Ensembl:ENSG00000137261|Vega:OTTHUMG00000014358 +9857 CEP350 HGNC:HGNC:24238|Ensembl:ENSG00000135837|Vega:OTTHUMG00000035269 +9858 PPP1R26 MIM:614056|HGNC:HGNC:29089|Ensembl:ENSG00000196422|Vega:OTTHUMG00000020904 +9859 CEP170 MIM:613023|HGNC:HGNC:28920|Ensembl:ENSG00000143702|Vega:OTTHUMG00000039862 +9860 LRIG2 MIM:608869|HGNC:HGNC:20889|Ensembl:ENSG00000198799|Vega:OTTHUMG00000012133 +9861 PSMD6 HGNC:HGNC:9564|Ensembl:ENSG00000163636|Vega:OTTHUMG00000158765 +9862 MED24 MIM:607000|HGNC:HGNC:22963|Ensembl:ENSG00000008838|Vega:OTTHUMG00000133329 +9863 MAGI2 MIM:606382|HGNC:HGNC:18957|Ensembl:ENSG00000187391|Vega:OTTHUMG00000130697 +9865 TRIL MIM:613356|HGNC:HGNC:22200|Ensembl:ENSG00000255690|Vega:OTTHUMG00000152829 +9866 TRIM66 MIM:612000|HGNC:HGNC:29005|Ensembl:ENSG00000166436|Vega:OTTHUMG00000150481 +9867 PJA2 HGNC:HGNC:17481|Ensembl:ENSG00000198961|Vega:OTTHUMG00000128750 +9868 TOMM70 MIM:606081|HGNC:HGNC:11985|Ensembl:ENSG00000154174|Vega:OTTHUMG00000159065 +9869 SETDB1 MIM:604396|HGNC:HGNC:10761|Ensembl:ENSG00000143379|Vega:OTTHUMG00000035003 +9870 AREL1 MIM:615380|HGNC:HGNC:20363|Ensembl:ENSG00000119682|Vega:OTTHUMG00000154499 +9871 SEC24D MIM:607186|HGNC:HGNC:10706|Ensembl:ENSG00000150961|Vega:OTTHUMG00000132957 +9873 FCHSD2 MIM:617556|HGNC:HGNC:29114|Ensembl:ENSG00000137478|Vega:OTTHUMG00000153082 +9874 TLK1 MIM:608438|HGNC:HGNC:11841|Ensembl:ENSG00000198586|Vega:OTTHUMG00000132243 +9875 URB1 MIM:608865|HGNC:HGNC:17344|Ensembl:ENSG00000142207|Vega:OTTHUMG00000064919 +9877 ZC3H11A MIM:613513|HGNC:HGNC:29093|Ensembl:ENSG00000058673|Ensembl:ENSG00000257315|Vega:OTTHUMG00000035909 +9878 TOX4 MIM:614032|HGNC:HGNC:20161|Ensembl:ENSG00000092203|Vega:OTTHUMG00000150278 +9879 DDX46 HGNC:HGNC:18681|Ensembl:ENSG00000145833|Vega:OTTHUMG00000163072 +9880 ZBTB39 HGNC:HGNC:29014|Ensembl:ENSG00000166860|Vega:OTTHUMG00000171007 +9881 TRANK1 HGNC:HGNC:29011|Ensembl:ENSG00000168016|Vega:OTTHUMG00000155848 +9882 TBC1D4 MIM:612465|HGNC:HGNC:19165|Ensembl:ENSG00000136111|Vega:OTTHUMG00000017088 +9883 POM121 MIM:615753|HGNC:HGNC:19702|Ensembl:ENSG00000196313|Vega:OTTHUMG00000023527 +9884 LRRC37A MIM:616555|HGNC:HGNC:29069|Ensembl:ENSG00000176681|Vega:OTTHUMG00000149841 +9885 OSBPL2 MIM:606731|HGNC:HGNC:15761|Ensembl:ENSG00000130703|Vega:OTTHUMG00000032909 +9886 RHOBTB1 MIM:607351|HGNC:HGNC:18738|Ensembl:ENSG00000072422|Vega:OTTHUMG00000018292 +9887 SMG7 MIM:610964|HGNC:HGNC:16792|Ensembl:ENSG00000116698|Vega:OTTHUMG00000035221 +9889 ZBED4 MIM:612552|HGNC:HGNC:20721|Ensembl:ENSG00000100426|Vega:OTTHUMG00000150291 +9890 PLPPR4 MIM:607813|HGNC:HGNC:23496|Ensembl:ENSG00000117600|Vega:OTTHUMG00000010763 +9891 NUAK1 MIM:608130|HGNC:HGNC:14311|Ensembl:ENSG00000074590|Vega:OTTHUMG00000169763 +9892 SNAP91 MIM:607923|HGNC:HGNC:14986|Ensembl:ENSG00000065609|Vega:OTTHUMG00000015114 +9894 TELO2 MIM:611140|HGNC:HGNC:29099|Ensembl:ENSG00000100726|Vega:OTTHUMG00000044471 +9895 TECPR2 MIM:615000|HGNC:HGNC:19957|Ensembl:ENSG00000196663|Vega:OTTHUMG00000171776 +9896 FIG4 MIM:609390|HGNC:HGNC:16873|Ensembl:ENSG00000112367|Vega:OTTHUMG00000015352 +9897 WASHC5 MIM:610657|HGNC:HGNC:28984|Ensembl:ENSG00000164961|Vega:OTTHUMG00000164991 +9898 UBAP2L MIM:616472|HGNC:HGNC:29877|Ensembl:ENSG00000143569|Vega:OTTHUMG00000035983 +9899 SV2B MIM:185861|HGNC:HGNC:16874|Ensembl:ENSG00000185518|Vega:OTTHUMG00000149833 +9900 SV2A MIM:185860|HGNC:HGNC:20566|Ensembl:ENSG00000159164|Vega:OTTHUMG00000012209 +9901 SRGAP3 MIM:606525|HGNC:HGNC:19744|Ensembl:ENSG00000196220|Vega:OTTHUMG00000090589 +9902 MRC2 MIM:612264|HGNC:HGNC:16875|Ensembl:ENSG00000011028|Vega:OTTHUMG00000179178 +9903 KLHL21 MIM:616262|HGNC:HGNC:29041|Ensembl:ENSG00000162413|Vega:OTTHUMG00000001437 +9904 RBM19 MIM:616444|HGNC:HGNC:29098|Ensembl:ENSG00000122965|Vega:OTTHUMG00000169646 +9905 SGSM2 MIM:611418|HGNC:HGNC:29026|Ensembl:ENSG00000141258|Vega:OTTHUMG00000177637 +9906 SLC35E2 HGNC:HGNC:20863|Ensembl:ENSG00000215790|Vega:OTTHUMG00000000823 +9907 AP5Z1 MIM:613653|HGNC:HGNC:22197|Ensembl:ENSG00000242802|Vega:OTTHUMG00000151754 +9908 G3BP2 HGNC:HGNC:30291|Ensembl:ENSG00000138757|Vega:OTTHUMG00000130097 +9909 DENND4B HGNC:HGNC:29044|Ensembl:ENSG00000198837|Vega:OTTHUMG00000037157 +9910 RABGAP1L MIM:609238|HGNC:HGNC:24663|Ensembl:ENSG00000152061|Vega:OTTHUMG00000034899 +9911 TMCC2 HGNC:HGNC:24239|Ensembl:ENSG00000133069|Vega:OTTHUMG00000037195 +9912 ARHGAP44 HGNC:HGNC:29096|Ensembl:ENSG00000006740|Vega:OTTHUMG00000058765 +9913 SUPT7L MIM:612762|HGNC:HGNC:30632|Ensembl:ENSG00000119760|Vega:OTTHUMG00000151947 +9914 ATP2C2 MIM:613082|HGNC:HGNC:29103|Ensembl:ENSG00000064270|Vega:OTTHUMG00000176737 +9915 ARNT2 MIM:606036|HGNC:HGNC:16876|Ensembl:ENSG00000172379|Vega:OTTHUMG00000165478 +9917 FAM20B MIM:611063|HGNC:HGNC:23017|Ensembl:ENSG00000116199|Vega:OTTHUMG00000035073 +9918 NCAPD2 MIM:615638|HGNC:HGNC:24305|Ensembl:ENSG00000010292|Vega:OTTHUMG00000168513 +9919 SEC16A MIM:612854|HGNC:HGNC:29006|Ensembl:ENSG00000148396|Vega:OTTHUMG00000020932 +9920 KBTBD11 HGNC:HGNC:29104|Ensembl:ENSG00000176595|Vega:OTTHUMG00000163629 +9921 RNF10 MIM:615998|HGNC:HGNC:10055|Ensembl:ENSG00000022840|Vega:OTTHUMG00000168999 +9922 IQSEC1 MIM:610166|HGNC:HGNC:29112|Ensembl:ENSG00000144711|Vega:OTTHUMG00000155398 +9923 ZBTB40 MIM:612106|HGNC:HGNC:29045|Ensembl:ENSG00000184677|Vega:OTTHUMG00000002897 +9924 PAN2 MIM:617447|HGNC:HGNC:20074|Ensembl:ENSG00000135473|Vega:OTTHUMG00000170412 +9925 ZBTB5 MIM:616590|HGNC:HGNC:23836|Ensembl:ENSG00000168795|Vega:OTTHUMG00000019918 +9926 LPGAT1 MIM:610473|HGNC:HGNC:28985|Ensembl:ENSG00000123684|Vega:OTTHUMG00000037120 +9927 MFN2 MIM:608507|HGNC:HGNC:16877|Ensembl:ENSG00000116688|Vega:OTTHUMG00000002392 +9928 KIF14 MIM:611279|HGNC:HGNC:19181|Ensembl:ENSG00000118193|Vega:OTTHUMG00000035723 +9929 JOSD1 MIM:615323|HGNC:HGNC:28953|Ensembl:ENSG00000100221|Vega:OTTHUMG00000151030 +9931 HELZ MIM:606699|HGNC:HGNC:16878|Ensembl:ENSG00000198265|Vega:OTTHUMG00000179555 +9933 PUM3 MIM:609960|HGNC:HGNC:29676|Ensembl:ENSG00000080608|Vega:OTTHUMG00000019450 +9934 P2RY14 MIM:610116|HGNC:HGNC:16442|Ensembl:ENSG00000174944|Vega:OTTHUMG00000159859 +9935 MAFB MIM:608968|HGNC:HGNC:6408|Ensembl:ENSG00000204103|Vega:OTTHUMG00000033052 +9936 CD302 MIM:612246|HGNC:HGNC:30843|Ensembl:ENSG00000241399|Vega:OTTHUMG00000154080 +9937 DCLRE1A MIM:609682|HGNC:HGNC:17660|Ensembl:ENSG00000198924|Vega:OTTHUMG00000019077 +9938 ARHGAP25 MIM:610587|HGNC:HGNC:28951|Ensembl:ENSG00000163219|Vega:OTTHUMG00000152621 +9939 RBM8A MIM:605313|HGNC:HGNC:9905|Ensembl:ENSG00000265241|Vega:OTTHUMG00000013736 +9940 DLEC1 MIM:604050|HGNC:HGNC:2899|Ensembl:ENSG00000008226|Vega:OTTHUMG00000131085 +9941 EXOG MIM:604051|HGNC:HGNC:3347|Ensembl:ENSG00000157036|Vega:OTTHUMG00000131295 +9942 XYLB MIM:604049|HGNC:HGNC:12839|Ensembl:ENSG00000093217|Vega:OTTHUMG00000131294 +9943 OXSR1 MIM:604046|HGNC:HGNC:8508|Ensembl:ENSG00000172939|Vega:OTTHUMG00000131084 +9945 GFPT2 MIM:603865|HGNC:HGNC:4242|Ensembl:ENSG00000131459|Vega:OTTHUMG00000163442 +9946 CRYZL1 MIM:603920|HGNC:HGNC:2420|Ensembl:ENSG00000205758|Vega:OTTHUMG00000065954 +9947 MAGEC1 MIM:300223|HGNC:HGNC:6812|Ensembl:ENSG00000155495|Vega:OTTHUMG00000022569 +9948 WDR1 MIM:604734|HGNC:HGNC:12754|Ensembl:ENSG00000071127|Vega:OTTHUMG00000160253 +9949 AMMECR1 MIM:300195|HGNC:HGNC:467|Ensembl:ENSG00000101935|Vega:OTTHUMG00000022197 +9950 GOLGA5 MIM:606918|HGNC:HGNC:4428|Ensembl:ENSG00000066455|Vega:OTTHUMG00000171217 +9951 HS3ST4 MIM:604059|HGNC:HGNC:5200|Ensembl:ENSG00000182601|Vega:OTTHUMG00000059978 +9953 HS3ST3B1 MIM:604058|HGNC:HGNC:5198|Ensembl:ENSG00000125430|Vega:OTTHUMG00000058810 +9955 HS3ST3A1 MIM:604057|HGNC:HGNC:5196|Ensembl:ENSG00000153976|Vega:OTTHUMG00000058768 +9956 HS3ST2 MIM:604056|HGNC:HGNC:5195|Ensembl:ENSG00000122254|Vega:OTTHUMG00000094785 +9957 HS3ST1 MIM:603244|HGNC:HGNC:5194|Ensembl:ENSG00000002587|Vega:OTTHUMG00000090547 +9958 USP15 MIM:604731|HGNC:HGNC:12613|Ensembl:ENSG00000135655|Vega:OTTHUMG00000170186 +9959 USP12P1 MIM:603091|HGNC:HGNC:12610 +9960 USP3 MIM:604728|HGNC:HGNC:12626|Ensembl:ENSG00000140455|Vega:OTTHUMG00000172309 +9961 MVP MIM:605088|HGNC:HGNC:7531|Ensembl:ENSG00000013364|Vega:OTTHUMG00000048227 +9962 SLC23A2 MIM:603791|HGNC:HGNC:10973|Ensembl:ENSG00000089057|Vega:OTTHUMG00000031793 +9963 SLC23A1 MIM:603790|HGNC:HGNC:10974|Ensembl:ENSG00000170482|Vega:OTTHUMG00000129228 +9964 MYCLP3 HGNC:HGNC:7557 +9965 FGF19 MIM:603891|HGNC:HGNC:3675|Ensembl:ENSG00000162344|Vega:OTTHUMG00000167886 +9966 TNFSF15 MIM:604052|HGNC:HGNC:11931|Ensembl:ENSG00000181634|Vega:OTTHUMG00000021011 +9967 THRAP3 MIM:603809|HGNC:HGNC:22964|Ensembl:ENSG00000054118|Vega:OTTHUMG00000007866 +9968 MED12 MIM:300188|HGNC:HGNC:11957|Ensembl:ENSG00000184634|Vega:OTTHUMG00000021788 +9969 MED13 MIM:603808|HGNC:HGNC:22474|Ensembl:ENSG00000108510|Vega:OTTHUMG00000179251 +9970 NR1I3 MIM:603881|HGNC:HGNC:7969|Ensembl:ENSG00000143257|Vega:OTTHUMG00000034347 +9971 NR1H4 MIM:603826|HGNC:HGNC:7967|Ensembl:ENSG00000012504|Vega:OTTHUMG00000170359 +9972 NUP153 MIM:603948|HGNC:HGNC:8062|Ensembl:ENSG00000124789|Vega:OTTHUMG00000014312 +9973 CCS MIM:603864|HGNC:HGNC:1613|Ensembl:ENSG00000173992|Vega:OTTHUMG00000167238 +9975 NR1D2 MIM:602304|HGNC:HGNC:7963|Ensembl:ENSG00000174738|Vega:OTTHUMG00000155659 +9976 CLEC2B MIM:603242|HGNC:HGNC:2053|Ensembl:ENSG00000110852|Vega:OTTHUMG00000168483 +9978 RBX1 MIM:603814|HGNC:HGNC:9928|Ensembl:ENSG00000100387|Vega:OTTHUMG00000151298 +9980 DOPEY2 MIM:604803|HGNC:HGNC:1291|Ensembl:ENSG00000142197|Vega:OTTHUMG00000086619 +9982 FGFBP1 MIM:607737|HGNC:HGNC:19695|Ensembl:ENSG00000137440|Vega:OTTHUMG00000097745 +9984 THOC1 MIM:606930|HGNC:HGNC:19070|Ensembl:ENSG00000079134|Vega:OTTHUMG00000178051 +9985 REC8 MIM:608193|HGNC:HGNC:16879|Ensembl:ENSG00000100918|Vega:OTTHUMG00000171916 +9986 RCE1 MIM:605385|HGNC:HGNC:13721|Ensembl:ENSG00000173653|Vega:OTTHUMG00000167098 +9987 HNRNPDL MIM:607137|HGNC:HGNC:5037|Ensembl:ENSG00000152795|Vega:OTTHUMG00000130299 +9988 DMTF1 MIM:608491|HGNC:HGNC:14603|Ensembl:ENSG00000135164|Vega:OTTHUMG00000154135 +9989 PPP4R1 MIM:604908|HGNC:HGNC:9320|Ensembl:ENSG00000154845|Vega:OTTHUMG00000137466 +9990 SLC12A6 MIM:604878|HGNC:HGNC:10914|Ensembl:ENSG00000140199|Vega:OTTHUMG00000129441 +9991 PTBP3 MIM:607527|HGNC:HGNC:10253|Ensembl:ENSG00000119314|Vega:OTTHUMG00000020503 +9992 KCNE2 MIM:603796|HGNC:HGNC:6242|Ensembl:ENSG00000159197|Vega:OTTHUMG00000086189 +9993 DGCR2 MIM:600594|HGNC:HGNC:2845|Ensembl:ENSG00000070413|Vega:OTTHUMG00000150141 +9994 CASP8AP2 MIM:606880|HGNC:HGNC:1510|Ensembl:ENSG00000118412 +9995 ELK2BP HGNC:HGNC:3324 +9997 SCO2 MIM:604272|HGNC:HGNC:10604|Ensembl:ENSG00000130489|Ensembl:ENSG00000284194|Vega:OTTHUMG00000191637 +10000 AKT3 MIM:611223|HGNC:HGNC:393|Ensembl:ENSG00000117020|Vega:OTTHUMG00000039994 +10001 MED6 MIM:602984|HGNC:HGNC:19970|Ensembl:ENSG00000133997|Vega:OTTHUMG00000171252 +10002 NR2E3 MIM:604485|HGNC:HGNC:7974|Ensembl:ENSG00000278570|Vega:OTTHUMG00000172841 +10003 NAALAD2 MIM:611636|HGNC:HGNC:14526|Ensembl:ENSG00000077616|Vega:OTTHUMG00000166368 +10004 NAALADL1 MIM:602640|HGNC:HGNC:23536|Ensembl:ENSG00000168060|Vega:OTTHUMG00000165595 +10005 ACOT8 MIM:608123|HGNC:HGNC:15919|Ensembl:ENSG00000101473|Vega:OTTHUMG00000033045 +10006 ABI1 MIM:603050|HGNC:HGNC:11320|Ensembl:ENSG00000136754|Vega:OTTHUMG00000017848 +10007 GNPDA1 MIM:601798|HGNC:HGNC:4417|Ensembl:ENSG00000113552|Vega:OTTHUMG00000129657 +10008 KCNE3 MIM:604433|HGNC:HGNC:6243|Ensembl:ENSG00000175538|Vega:OTTHUMG00000165641 +10009 ZBTB33 MIM:300329|HGNC:HGNC:16682|Ensembl:ENSG00000177485|Vega:OTTHUMG00000171159 +10010 TANK MIM:603893|HGNC:HGNC:11562|Ensembl:ENSG00000136560|Vega:OTTHUMG00000132037 +10011 SRA1 MIM:603819|HGNC:HGNC:11281|Ensembl:ENSG00000213523|Vega:OTTHUMG00000163569 +10013 HDAC6 MIM:300272|HGNC:HGNC:14064|Ensembl:ENSG00000094631|Vega:OTTHUMG00000034496 +10014 HDAC5 MIM:605315|HGNC:HGNC:14068|Ensembl:ENSG00000108840|Vega:OTTHUMG00000181806 +10015 PDCD6IP MIM:608074|HGNC:HGNC:8766|Ensembl:ENSG00000170248|Vega:OTTHUMG00000130751 +10016 PDCD6 MIM:601057|HGNC:HGNC:8765|Ensembl:ENSG00000249915|Vega:OTTHUMG00000090283 +10017 BCL2L10 MIM:606910|HGNC:HGNC:993|Ensembl:ENSG00000137875|Vega:OTTHUMG00000131893 +10018 BCL2L11 MIM:603827|HGNC:HGNC:994|Ensembl:ENSG00000153094|Vega:OTTHUMG00000131256 +10019 SH2B3 MIM:605093|HGNC:HGNC:29605|Ensembl:ENSG00000111252|Vega:OTTHUMG00000169550 +10020 GNE MIM:603824|HGNC:HGNC:23657|Ensembl:ENSG00000159921|Vega:OTTHUMG00000019899 +10021 HCN4 MIM:605206|HGNC:HGNC:16882|Ensembl:ENSG00000138622|Vega:OTTHUMG00000137563 +10022 INSL5 MIM:606413|HGNC:HGNC:6088|Ensembl:ENSG00000172410|Vega:OTTHUMG00000009164 +10023 FRAT1 MIM:602503|HGNC:HGNC:3944|Ensembl:ENSG00000165879|Vega:OTTHUMG00000018848 +10024 TROAP MIM:603872|HGNC:HGNC:12327|Ensembl:ENSG00000135451|Vega:OTTHUMG00000169486 +10025 MED16 MIM:604062|HGNC:HGNC:17556|Ensembl:ENSG00000175221|Vega:OTTHUMG00000181841 +10026 PIGK MIM:605087|HGNC:HGNC:8965|Ensembl:ENSG00000142892|Vega:OTTHUMG00000009686 +10029 CASKP1 HGNC:HGNC:1498 +10031 SHROOM2P1 HGNC:HGNC:631 +10033 ARSEP1 HGNC:HGNC:720 +10034 ARSDP1 HGNC:HGNC:718 +10036 CHAF1A MIM:601246|HGNC:HGNC:1910|Ensembl:ENSG00000167670|Vega:OTTHUMG00000181922 +10038 PARP2 MIM:607725|HGNC:HGNC:272|Ensembl:ENSG00000129484|Vega:OTTHUMG00000166106 +10039 PARP3 MIM:607726|HGNC:HGNC:273|Ensembl:ENSG00000041880|Vega:OTTHUMG00000156931 +10040 TOM1L1 MIM:604701|HGNC:HGNC:11983|Ensembl:ENSG00000141198|Vega:OTTHUMG00000177816 +10042 HMGXB4 MIM:604702|HGNC:HGNC:5003|Ensembl:ENSG00000100281|Vega:OTTHUMG00000150439 +10043 TOM1 MIM:604700|HGNC:HGNC:11982|Ensembl:ENSG00000100284|Vega:OTTHUMG00000150958 +10044 SH2D3C MIM:604722|HGNC:HGNC:16884|Ensembl:ENSG00000095370|Vega:OTTHUMG00000020717 +10045 SH2D3A MIM:604721|HGNC:HGNC:16885|Ensembl:ENSG00000125731|Vega:OTTHUMG00000181868 +10046 MAMLD1 MIM:300120|HGNC:HGNC:2568|Ensembl:ENSG00000013619|Vega:OTTHUMG00000024157 +10047 CST8 MIM:608683|HGNC:HGNC:2480|Ensembl:ENSG00000125815|Vega:OTTHUMG00000032071 +10048 RANBP9 MIM:603854|HGNC:HGNC:13727|Ensembl:ENSG00000010017|Vega:OTTHUMG00000015642 +10049 DNAJB6 MIM:611332|HGNC:HGNC:14888|Ensembl:ENSG00000105993|Vega:OTTHUMG00000157242 +10050 SLC17A4 MIM:604216|HGNC:HGNC:10932|Ensembl:ENSG00000146039|Vega:OTTHUMG00000014410 +10051 SMC4 MIM:605575|HGNC:HGNC:14013|Ensembl:ENSG00000113810|Vega:OTTHUMG00000159006 +10052 GJC1 MIM:608655|HGNC:HGNC:4280|Ensembl:ENSG00000182963|Vega:OTTHUMG00000179861 +10053 AP1M2 MIM:607309|HGNC:HGNC:558|Ensembl:ENSG00000129354|Vega:OTTHUMG00000180584 +10054 UBA2 MIM:613295|HGNC:HGNC:30661|Ensembl:ENSG00000126261|Vega:OTTHUMG00000182090 +10055 SAE1 MIM:613294|HGNC:HGNC:30660|Ensembl:ENSG00000142230|Vega:OTTHUMG00000183464 +10056 FARSB MIM:609690|HGNC:HGNC:17800|Ensembl:ENSG00000116120|Vega:OTTHUMG00000133155 +10057 ABCC5 MIM:605251|HGNC:HGNC:56|Ensembl:ENSG00000114770|Vega:OTTHUMG00000156871 +10058 ABCB6 MIM:605452|HGNC:HGNC:47|Ensembl:ENSG00000115657|Vega:OTTHUMG00000133131 +10059 DNM1L MIM:603850|HGNC:HGNC:2973|Ensembl:ENSG00000087470|Vega:OTTHUMG00000169451 +10060 ABCC9 MIM:601439|HGNC:HGNC:60|Ensembl:ENSG00000069431|Vega:OTTHUMG00000169094 +10061 ABCF2 MIM:612510|HGNC:HGNC:71|Ensembl:ENSG00000033050|Vega:OTTHUMG00000154570 +10062 NR1H3 MIM:602423|HGNC:HGNC:7966|Ensembl:ENSG00000025434|Vega:OTTHUMG00000150628 +10063 COX17 MIM:604813|HGNC:HGNC:2264|Ensembl:ENSG00000138495|Vega:OTTHUMG00000159433 +10064 VDAC1P2 HGNC:HGNC:12670 +10066 SCAMP2 MIM:606912|HGNC:HGNC:10564|Ensembl:ENSG00000140497|Vega:OTTHUMG00000142817 +10067 SCAMP3 MIM:606913|HGNC:HGNC:10565|Ensembl:ENSG00000116521|Vega:OTTHUMG00000035874 +10068 IL18BP MIM:604113|HGNC:HGNC:5987|Ensembl:ENSG00000137496|Vega:OTTHUMG00000133713 +10069 RWDD2B HGNC:HGNC:1302|Ensembl:ENSG00000156253|Vega:OTTHUMG00000078805 +10071 MUC12 MIM:604609|HGNC:HGNC:7510|Ensembl:ENSG00000205277|Vega:OTTHUMG00000157042 +10072 DPP3 MIM:606818|HGNC:HGNC:3008|Ensembl:ENSG00000254986|Vega:OTTHUMG00000167143 +10073 SNUPN MIM:607902|HGNC:HGNC:14245|Ensembl:ENSG00000169371|Vega:OTTHUMG00000142833 +10075 HUWE1 MIM:300697|HGNC:HGNC:30892|Ensembl:ENSG00000086758|Vega:OTTHUMG00000021617 +10076 PTPRU MIM:602454|HGNC:HGNC:9683|Ensembl:ENSG00000060656|Vega:OTTHUMG00000003699 +10077 TSPAN32 MIM:603853|HGNC:HGNC:13410|Ensembl:ENSG00000064201|Vega:OTTHUMG00000009762 +10078 TSSC4 MIM:603852|HGNC:HGNC:12386|Ensembl:ENSG00000184281|Vega:OTTHUMG00000009895 +10079 ATP9A MIM:609126|HGNC:HGNC:13540|Ensembl:ENSG00000054793|Vega:OTTHUMG00000032751 +10081 PDCD7 MIM:608138|HGNC:HGNC:8767|Ensembl:ENSG00000090470|Vega:OTTHUMG00000133117 +10082 GPC6 MIM:604404|HGNC:HGNC:4454|Ensembl:ENSG00000183098|Vega:OTTHUMG00000017205 +10083 USH1C MIM:605242|HGNC:HGNC:12597|Ensembl:ENSG00000006611|Vega:OTTHUMG00000166323 +10084 PQBP1 MIM:300463|HGNC:HGNC:9330|Ensembl:ENSG00000102103|Vega:OTTHUMG00000024128 +10085 EDIL3 MIM:606018|HGNC:HGNC:3173|Ensembl:ENSG00000164176|Vega:OTTHUMG00000119047 +10086 HHLA1 MIM:604109|HGNC:HGNC:4904|Ensembl:ENSG00000132297|Vega:OTTHUMG00000140390 +10087 COL4A3BP MIM:604677|HGNC:HGNC:2205|Ensembl:ENSG00000113163|Vega:OTTHUMG00000102068 +10089 KCNK7 MIM:603940|HGNC:HGNC:6282|Ensembl:ENSG00000173338|Vega:OTTHUMG00000166528 +10090 UST MIM:610752|HGNC:HGNC:17223|Ensembl:ENSG00000111962|Vega:OTTHUMG00000016135 +10092 ARPC5 MIM:604227|HGNC:HGNC:708|Ensembl:ENSG00000162704|Vega:OTTHUMG00000035326 +10093 ARPC4 MIM:604226|HGNC:HGNC:707|Ensembl:ENSG00000241553|Ensembl:ENSG00000250151|Vega:OTTHUMG00000133768|Vega:OTTHUMG00000161408 +10094 ARPC3 MIM:604225|HGNC:HGNC:706|Ensembl:ENSG00000111229|Vega:OTTHUMG00000134333 +10095 ARPC1B MIM:604223|HGNC:HGNC:704|Ensembl:ENSG00000130429|Vega:OTTHUMG00000154552 +10096 ACTR3 MIM:604222|HGNC:HGNC:170|Ensembl:ENSG00000115091|Vega:OTTHUMG00000153497 +10097 ACTR2 MIM:604221|HGNC:HGNC:169|Ensembl:ENSG00000138071|Vega:OTTHUMG00000129540 +10098 TSPAN5 MIM:613136|HGNC:HGNC:17753|Ensembl:ENSG00000168785|Vega:OTTHUMG00000131008 +10099 TSPAN3 MIM:613134|HGNC:HGNC:17752|Ensembl:ENSG00000140391|Vega:OTTHUMG00000143728 +10100 TSPAN2 MIM:613133|HGNC:HGNC:20659|Ensembl:ENSG00000134198|Vega:OTTHUMG00000011878 +10101 NUBP2 MIM:610779|HGNC:HGNC:8042|Ensembl:ENSG00000095906|Vega:OTTHUMG00000128639 +10102 TSFM MIM:604723|HGNC:HGNC:12367|Ensembl:ENSG00000123297|Vega:OTTHUMG00000153042 +10103 TSPAN1 MIM:613170|HGNC:HGNC:20657|Ensembl:ENSG00000117472|Vega:OTTHUMG00000007602 +10105 PPIF MIM:604486|HGNC:HGNC:9259|Ensembl:ENSG00000108179|Vega:OTTHUMG00000018562 +10106 CTDSP2 MIM:608711|HGNC:HGNC:17077|Ensembl:ENSG00000175215|Vega:OTTHUMG00000170483 +10107 TRIM10 MIM:605701|HGNC:HGNC:10072|Ensembl:ENSG00000204613|Vega:OTTHUMG00000031295 +10108 MKRN3-AS1 MIM:603857|HGNC:HGNC:12910 +10109 ARPC2 MIM:604224|HGNC:HGNC:705|Ensembl:ENSG00000163466|Vega:OTTHUMG00000133618 +10110 SGK2 MIM:607589|HGNC:HGNC:13900|Ensembl:ENSG00000101049|Vega:OTTHUMG00000033054 +10111 RAD50 MIM:604040|HGNC:HGNC:9816|Ensembl:ENSG00000113522|Vega:OTTHUMG00000059613 +10112 KIF20A MIM:605664|HGNC:HGNC:9787|Ensembl:ENSG00000112984|Vega:OTTHUMG00000129195 +10113 PREB MIM:606395|HGNC:HGNC:9356|Ensembl:ENSG00000138073|Vega:OTTHUMG00000097076 +10114 HIPK3 MIM:604424|HGNC:HGNC:4915|Ensembl:ENSG00000110422|Vega:OTTHUMG00000132269 +10116 FEM1B MIM:613539|HGNC:HGNC:3649|Ensembl:ENSG00000169018|Vega:OTTHUMG00000133285 +10117 ENAM MIM:606585|HGNC:HGNC:3344|Ensembl:ENSG00000132464|Vega:OTTHUMG00000129914 +10118 EMWX MIM:300211|HGNC:HGNC:3339 +10120 ACTR1B MIM:605144|HGNC:HGNC:168|Ensembl:ENSG00000115073|Vega:OTTHUMG00000130549 +10121 ACTR1A MIM:605143|HGNC:HGNC:167|Ensembl:ENSG00000138107|Vega:OTTHUMG00000018956 +10123 ARL4C MIM:604787|HGNC:HGNC:698|Ensembl:ENSG00000188042|Vega:OTTHUMG00000133291 +10124 ARL4A MIM:604786|HGNC:HGNC:695|Ensembl:ENSG00000122644|Vega:OTTHUMG00000023374 +10125 RASGRP1 MIM:603962|HGNC:HGNC:9878|Ensembl:ENSG00000172575|Vega:OTTHUMG00000172379 +10126 DNAL4 MIM:610565|HGNC:HGNC:2955|Ensembl:ENSG00000100246|Vega:OTTHUMG00000151025 +10127 ZNF263 MIM:604191|HGNC:HGNC:13056|Ensembl:ENSG00000006194|Vega:OTTHUMG00000129323 +10128 LRPPRC MIM:607544|HGNC:HGNC:15714|Ensembl:ENSG00000138095|Vega:OTTHUMG00000152782 +10129 FRY MIM:614818|HGNC:HGNC:20367|Ensembl:ENSG00000073910|Vega:OTTHUMG00000016696 +10130 PDIA6 MIM:611099|HGNC:HGNC:30168|Ensembl:ENSG00000143870|Vega:OTTHUMG00000090479 +10131 TRAP1 MIM:606219|HGNC:HGNC:16264|Ensembl:ENSG00000126602|Vega:OTTHUMG00000129427 +10133 OPTN MIM:602432|HGNC:HGNC:17142|Ensembl:ENSG00000123240|Vega:OTTHUMG00000017690 +10134 BCAP31 MIM:300398|HGNC:HGNC:16695|Ensembl:ENSG00000185825|Vega:OTTHUMG00000024218 +10135 NAMPT MIM:608764|HGNC:HGNC:30092|Ensembl:ENSG00000105835|Vega:OTTHUMG00000140388 +10136 CELA3A HGNC:HGNC:15944|Ensembl:ENSG00000142789|Vega:OTTHUMG00000002755 +10137 RBM12 MIM:607179|HGNC:HGNC:9898|Ensembl:ENSG00000244462|Vega:OTTHUMG00000032350 +10138 YAF2 MIM:607534|HGNC:HGNC:17363|Ensembl:ENSG00000015153|Vega:OTTHUMG00000169380 +10139 ARFRP1 MIM:604699|HGNC:HGNC:662|Ensembl:ENSG00000101246|Vega:OTTHUMG00000032993 +10140 TOB1 MIM:605523|HGNC:HGNC:11979|Ensembl:ENSG00000141232|Vega:OTTHUMG00000162277 +10141 LINC01587 HGNC:HGNC:13716|Ensembl:ENSG00000082929 +10142 AKAP9 MIM:604001|HGNC:HGNC:379|Ensembl:ENSG00000127914|Vega:OTTHUMG00000131127 +10143 CLEC3A MIM:613588|HGNC:HGNC:2052|Ensembl:ENSG00000166509|Vega:OTTHUMG00000137620 +10144 FAM13A MIM:613299|HGNC:HGNC:19367|Ensembl:ENSG00000138640|Vega:OTTHUMG00000161006 +10146 G3BP1 MIM:608431|HGNC:HGNC:30292|Ensembl:ENSG00000145907|Vega:OTTHUMG00000130123 +10147 SUGP2 MIM:607993|HGNC:HGNC:18641|Ensembl:ENSG00000064607|Vega:OTTHUMG00000182997 +10148 EBI3 MIM:605816|HGNC:HGNC:3129|Ensembl:ENSG00000105246|Vega:OTTHUMG00000181866 +10149 ADGRG2 MIM:300572|HGNC:HGNC:4516|Ensembl:ENSG00000173698|Vega:OTTHUMG00000021223 +10150 MBNL2 MIM:607327|HGNC:HGNC:16746|Ensembl:ENSG00000139793|Vega:OTTHUMG00000017239 +10151 HNRNPA3P1 HGNC:HGNC:13729 +10152 ABI2 MIM:606442|HGNC:HGNC:24011|Ensembl:ENSG00000138443|Vega:OTTHUMG00000132879 +10153 CEBPZ MIM:612828|HGNC:HGNC:24218|Ensembl:ENSG00000115816|Vega:OTTHUMG00000100960 +10154 PLXNC1 MIM:604259|HGNC:HGNC:9106|Ensembl:ENSG00000136040|Vega:OTTHUMG00000170235 +10155 TRIM28 MIM:601742|HGNC:HGNC:16384|Ensembl:ENSG00000130726|Vega:OTTHUMG00000183546 +10156 RASA4 MIM:607943|HGNC:HGNC:23181|Ensembl:ENSG00000105808|Vega:OTTHUMG00000150383 +10157 AASS MIM:605113|HGNC:HGNC:17366|Ensembl:ENSG00000008311|Vega:OTTHUMG00000157058 +10158 PDZK1IP1 MIM:607178|HGNC:HGNC:16887|Ensembl:ENSG00000162366|Vega:OTTHUMG00000007852 +10159 ATP6AP2 MIM:300556|HGNC:HGNC:18305|Ensembl:ENSG00000182220|Vega:OTTHUMG00000024103 +10160 FARP1 MIM:602654|HGNC:HGNC:3591|Ensembl:ENSG00000152767|Vega:OTTHUMG00000017248 +10161 LPAR6 MIM:609239|HGNC:HGNC:15520|Ensembl:ENSG00000139679|Vega:OTTHUMG00000016895 +10162 LPCAT3 MIM:611950|HGNC:HGNC:30244|Ensembl:ENSG00000111684|Vega:OTTHUMG00000168970 +10163 WASF2 MIM:605875|HGNC:HGNC:12733|Ensembl:ENSG00000158195|Vega:OTTHUMG00000003393 +10164 CHST4 HGNC:HGNC:1972|Ensembl:ENSG00000140835|Vega:OTTHUMG00000137592 +10165 SLC25A13 MIM:603859|HGNC:HGNC:10983|Ensembl:ENSG00000004864|Vega:OTTHUMG00000023074 +10166 SLC25A15 MIM:603861|HGNC:HGNC:10985|Ensembl:ENSG00000102743|Vega:OTTHUMG00000016776 +10167 CFM1 MIM:603855|HGNC:HGNC:1881 +10168 ZNF197 HGNC:HGNC:12988|Ensembl:ENSG00000186448|Vega:OTTHUMG00000133089 +10169 SERF2 MIM:605054|HGNC:HGNC:10757|Ensembl:ENSG00000140264|Vega:OTTHUMG00000059935 +10170 DHRS9 MIM:612131|HGNC:HGNC:16888|Ensembl:ENSG00000073737|Vega:OTTHUMG00000132180 +10171 RCL1 MIM:611405|HGNC:HGNC:17687|Ensembl:ENSG00000120158|Vega:OTTHUMG00000019474 +10172 ZNF256 MIM:606956|HGNC:HGNC:13049|Ensembl:ENSG00000152454|Vega:OTTHUMG00000183449 +10174 SORBS3 MIM:610795|HGNC:HGNC:30907|Ensembl:ENSG00000120896|Vega:OTTHUMG00000131728 +10175 CNIH1 MIM:611287|HGNC:HGNC:19431|Ensembl:ENSG00000100528|Vega:OTTHUMG00000152335 +10178 TENM1 MIM:300588|HGNC:HGNC:8117|Ensembl:ENSG00000009694|Vega:OTTHUMG00000022721 +10179 RBM7 MIM:612413|HGNC:HGNC:9904|Ensembl:ENSG00000076053|Vega:OTTHUMG00000168270 +10180 RBM6 MIM:606886|HGNC:HGNC:9903|Ensembl:ENSG00000004534|Vega:OTTHUMG00000156736 +10181 RBM5 MIM:606884|HGNC:HGNC:9902|Ensembl:ENSG00000003756|Vega:OTTHUMG00000156785 +10184 LHFPL2 MIM:609718|HGNC:HGNC:6588|Ensembl:ENSG00000145685|Vega:OTTHUMG00000107579 +10186 LHFPL6 MIM:606710|HGNC:HGNC:6586|Ensembl:ENSG00000183722|Vega:OTTHUMG00000016767 +10187 VDAC1P5 HGNC:HGNC:12676 +10188 TNK2 MIM:606994|HGNC:HGNC:19297|Ensembl:ENSG00000061938|Vega:OTTHUMG00000155737 +10189 ALYREF MIM:604171|HGNC:HGNC:19071|Ensembl:ENSG00000183684|Vega:OTTHUMG00000160470 +10190 TXNDC9 MIM:612564|HGNC:HGNC:24110|Ensembl:ENSG00000115514|Vega:OTTHUMG00000130641 +10193 RNF41 HGNC:HGNC:18401|Ensembl:ENSG00000181852|Vega:OTTHUMG00000170328 +10194 TSHZ1 MIM:614427|HGNC:HGNC:10669|Ensembl:ENSG00000179981|Vega:OTTHUMG00000132859 +10195 ALG3 MIM:608750|HGNC:HGNC:23056|Ensembl:ENSG00000214160|Vega:OTTHUMG00000156823 +10196 PRMT3 MIM:603190|HGNC:HGNC:30163|Ensembl:ENSG00000185238|Vega:OTTHUMG00000166022 +10197 PSME3 MIM:605129|HGNC:HGNC:9570|Ensembl:ENSG00000131467|Vega:OTTHUMG00000180654 +10198 MPHOSPH9 MIM:605501|HGNC:HGNC:7215|Ensembl:ENSG00000051825|Vega:OTTHUMG00000168849 +10199 MPHOSPH10 MIM:605503|HGNC:HGNC:7213|Ensembl:ENSG00000124383|Vega:OTTHUMG00000129715 +10200 MPHOSPH6 MIM:605500|HGNC:HGNC:7214|Ensembl:ENSG00000135698|Vega:OTTHUMG00000137632 +10201 NME6 MIM:608294|HGNC:HGNC:20567|Ensembl:ENSG00000172113|Vega:OTTHUMG00000133531 +10202 DHRS2 MIM:615194|HGNC:HGNC:18349|Ensembl:ENSG00000100867|Vega:OTTHUMG00000028771 +10203 CALCRL MIM:114190|HGNC:HGNC:16709|Ensembl:ENSG00000064989|Vega:OTTHUMG00000132636 +10204 NUTF2 MIM:605813|HGNC:HGNC:13722|Ensembl:ENSG00000102898|Vega:OTTHUMG00000137540 +10205 MPZL2 MIM:604873|HGNC:HGNC:3496|Ensembl:ENSG00000149573|Vega:OTTHUMG00000166967 +10206 TRIM13 MIM:605661|HGNC:HGNC:9976|Ensembl:ENSG00000204977|Vega:OTTHUMG00000016926 +10207 PATJ MIM:603199|HGNC:HGNC:28881|Ensembl:ENSG00000132849|Vega:OTTHUMG00000008560 +10208 USPL1 MIM:617470|HGNC:HGNC:20294|Ensembl:ENSG00000132952|Vega:OTTHUMG00000016675 +10209 EIF1 HGNC:HGNC:3249|Ensembl:ENSG00000173812|Vega:OTTHUMG00000133492 +10210 TOPORS MIM:609507|HGNC:HGNC:21653|Ensembl:ENSG00000197579|Vega:OTTHUMG00000019743 +10211 FLOT1 MIM:606998|HGNC:HGNC:3757|Ensembl:ENSG00000137312|Vega:OTTHUMG00000031151 +10212 DDX39A HGNC:HGNC:17821|Ensembl:ENSG00000123136|Vega:OTTHUMG00000182181 +10213 PSMD14 MIM:607173|HGNC:HGNC:16889|Ensembl:ENSG00000115233|Vega:OTTHUMG00000153882 +10214 SSX3 MIM:300325|HGNC:HGNC:11337|Ensembl:ENSG00000165584|Vega:OTTHUMG00000021489 +10215 OLIG2 MIM:606386|HGNC:HGNC:9398|Ensembl:ENSG00000205927|Vega:OTTHUMG00000065032 +10216 PRG4 MIM:604283|HGNC:HGNC:9364|Ensembl:ENSG00000116690|Vega:OTTHUMG00000035574 +10217 CTDSPL MIM:608592|HGNC:HGNC:16890|Ensembl:ENSG00000144677|Vega:OTTHUMG00000155942 +10218 ANGPTL7 HGNC:HGNC:24078|Ensembl:ENSG00000171819|Vega:OTTHUMG00000002002 +10219 KLRG1 MIM:604874|HGNC:HGNC:6380|Ensembl:ENSG00000139187|Vega:OTTHUMG00000168277 +10220 GDF11 MIM:603936|HGNC:HGNC:4216|Ensembl:ENSG00000135414|Vega:OTTHUMG00000170188 +10221 TRIB1 MIM:609461|HGNC:HGNC:16891|Ensembl:ENSG00000173334|Vega:OTTHUMG00000165007 +10223 GPA33 MIM:602171|HGNC:HGNC:4445|Ensembl:ENSG00000143167|Vega:OTTHUMG00000034435 +10224 ZNF443 MIM:606697|HGNC:HGNC:20878|Ensembl:ENSG00000180855|Vega:OTTHUMG00000156404 +10225 CD96 MIM:606037|HGNC:HGNC:16892|Ensembl:ENSG00000153283|Vega:OTTHUMG00000159275 +10226 PLIN3 MIM:602702|HGNC:HGNC:16893|Ensembl:ENSG00000105355|Vega:OTTHUMG00000180249 +10227 MFSD10 MIM:610977|HGNC:HGNC:16894|Ensembl:ENSG00000109736|Vega:OTTHUMG00000122081 +10228 STX6 MIM:603944|HGNC:HGNC:11441|Ensembl:ENSG00000135823|Vega:OTTHUMG00000035179 +10229 COQ7 MIM:601683|HGNC:HGNC:2244|Ensembl:ENSG00000167186|Vega:OTTHUMG00000131455 +10230 NBR2 HGNC:HGNC:20691|Ensembl:ENSG00000198496 +10231 RCAN2 MIM:604876|HGNC:HGNC:3041|Ensembl:ENSG00000172348|Vega:OTTHUMG00000014782 +10232 MSLN MIM:601051|HGNC:HGNC:7371|Ensembl:ENSG00000102854|Vega:OTTHUMG00000047992 +10233 LRRC23 HGNC:HGNC:19138|Ensembl:ENSG00000010626|Vega:OTTHUMG00000156668 +10234 LRRC17 HGNC:HGNC:16895|Ensembl:ENSG00000128606|Vega:OTTHUMG00000157210 +10235 RASGRP2 MIM:605577|HGNC:HGNC:9879|Ensembl:ENSG00000068831|Vega:OTTHUMG00000045420 +10236 HNRNPR MIM:607201|HGNC:HGNC:5047|Ensembl:ENSG00000125944 +10237 SLC35B1 MIM:610790|HGNC:HGNC:20798|Ensembl:ENSG00000121073|Vega:OTTHUMG00000161638 +10238 DCAF7 MIM:605973|HGNC:HGNC:30915|Ensembl:ENSG00000136485|Vega:OTTHUMG00000178902 +10239 AP3S2 MIM:602416|HGNC:HGNC:571|Ensembl:ENSG00000157823|Vega:OTTHUMG00000149811 +10240 MRPS31 MIM:611992|HGNC:HGNC:16632|Ensembl:ENSG00000102738|Vega:OTTHUMG00000016777 +10241 CALCOCO2 MIM:604587|HGNC:HGNC:29912|Ensembl:ENSG00000136436|Vega:OTTHUMG00000160505 +10242 KCNMB2 MIM:605214|HGNC:HGNC:6286|Ensembl:ENSG00000197584|Ensembl:ENSG00000275163|Vega:OTTHUMG00000157264|Vega:OTTHUMG00000186539 +10243 GPHN MIM:603930|HGNC:HGNC:15465|Ensembl:ENSG00000171723|Vega:OTTHUMG00000029785 +10244 RABEPK MIM:605962|HGNC:HGNC:16896|Ensembl:ENSG00000136933|Vega:OTTHUMG00000020674 +10245 TIMM17B MIM:300249|HGNC:HGNC:17310|Ensembl:ENSG00000126768|Vega:OTTHUMG00000034498 +10246 SLC17A2 MIM:611049|HGNC:HGNC:10930|Ensembl:ENSG00000112337|Vega:OTTHUMG00000014413 +10247 RIDA MIM:602487|HGNC:HGNC:16897|Ensembl:ENSG00000132541|Vega:OTTHUMG00000164670 +10248 POP7 MIM:606113|HGNC:HGNC:19949|Ensembl:ENSG00000172336|Vega:OTTHUMG00000044311 +10249 GLYAT MIM:607424|HGNC:HGNC:13734|Ensembl:ENSG00000149124|Vega:OTTHUMG00000167429 +10250 SRRM1 MIM:605975|HGNC:HGNC:16638|Ensembl:ENSG00000133226|Vega:OTTHUMG00000003320 +10251 SPRY3 MIM:300531|HGNC:HGNC:11271|Ensembl:ENSG00000168939|Vega:OTTHUMG00000022675 +10252 SPRY1 MIM:602465|HGNC:HGNC:11269|Ensembl:ENSG00000164056|Vega:OTTHUMG00000133071 +10253 SPRY2 MIM:602466|HGNC:HGNC:11270|Ensembl:ENSG00000136158|Vega:OTTHUMG00000017140 +10254 STAM2 MIM:606244|HGNC:HGNC:11358|Ensembl:ENSG00000115145|Vega:OTTHUMG00000131885 +10255 HCG9 MIM:615797|HGNC:HGNC:21243|Ensembl:ENSG00000204625 +10256 CNKSR1 MIM:603272|HGNC:HGNC:19700|Ensembl:ENSG00000142675|Vega:OTTHUMG00000007541 +10257 ABCC4 MIM:605250|HGNC:HGNC:55|Ensembl:ENSG00000125257|Vega:OTTHUMG00000017216 +10260 DENND4A MIM:600382|HGNC:HGNC:24321|Ensembl:ENSG00000174485|Vega:OTTHUMG00000172635 +10261 IGSF6 MIM:606222|HGNC:HGNC:5953|Ensembl:ENSG00000140749|Vega:OTTHUMG00000090709 +10262 SF3B4 MIM:605593|HGNC:HGNC:10771|Ensembl:ENSG00000143368|Vega:OTTHUMG00000012208 +10263 CDK2AP2 HGNC:HGNC:30833|Ensembl:ENSG00000167797|Vega:OTTHUMG00000167676 +10265 IRX5 MIM:606195|HGNC:HGNC:14361|Ensembl:ENSG00000176842|Vega:OTTHUMG00000133201 +10266 RAMP2 MIM:605154|HGNC:HGNC:9844|Ensembl:ENSG00000131477|Vega:OTTHUMG00000180648 +10267 RAMP1 MIM:605153|HGNC:HGNC:9843|Ensembl:ENSG00000132329|Vega:OTTHUMG00000133337 +10268 RAMP3 MIM:605155|HGNC:HGNC:9845|Ensembl:ENSG00000122679|Vega:OTTHUMG00000023729 +10269 ZMPSTE24 MIM:606480|HGNC:HGNC:12877|Ensembl:ENSG00000084073|Vega:OTTHUMG00000005762 +10270 AKAP8 MIM:604692|HGNC:HGNC:378|Ensembl:ENSG00000105127|Vega:OTTHUMG00000182444 +10272 FSTL3 MIM:605343|HGNC:HGNC:3973|Ensembl:ENSG00000070404|Vega:OTTHUMG00000180593 +10273 STUB1 MIM:607207|HGNC:HGNC:11427|Ensembl:ENSG00000103266|Vega:OTTHUMG00000121140 +10274 STAG1 MIM:604358|HGNC:HGNC:11354|Ensembl:ENSG00000118007|Vega:OTTHUMG00000159798 +10276 NET1 MIM:606450|HGNC:HGNC:14592|Ensembl:ENSG00000173848|Vega:OTTHUMG00000017596 +10277 UBE4B MIM:613565|HGNC:HGNC:12500|Ensembl:ENSG00000130939|Vega:OTTHUMG00000001797 +10278 EFS MIM:609906|HGNC:HGNC:16898|Ensembl:ENSG00000100842|Vega:OTTHUMG00000028741 +10279 PRSS16 MIM:607169|HGNC:HGNC:9480|Ensembl:ENSG00000112812|Vega:OTTHUMG00000016167 +10280 SIGMAR1 MIM:601978|HGNC:HGNC:8157|Ensembl:ENSG00000147955|Vega:OTTHUMG00000019829 +10281 DSCR4 MIM:604829|HGNC:HGNC:3045|Ensembl:ENSG00000184029|Vega:OTTHUMG00000086673 +10282 BET1 MIM:605456|HGNC:HGNC:14562|Ensembl:ENSG00000105829|Vega:OTTHUMG00000023487 +10283 CWC27 MIM:617170|HGNC:HGNC:10664|Ensembl:ENSG00000153015|Vega:OTTHUMG00000074069 +10284 SAP18 MIM:602949|HGNC:HGNC:10530|Ensembl:ENSG00000150459|Vega:OTTHUMG00000016535 +10285 SMNDC1 MIM:603519|HGNC:HGNC:16900|Ensembl:ENSG00000119953|Vega:OTTHUMG00000019036 +10286 BCAS2 MIM:605783|HGNC:HGNC:975|Ensembl:ENSG00000116752|Vega:OTTHUMG00000011898 +10287 RGS19 MIM:605071|HGNC:HGNC:13735|Ensembl:ENSG00000171700|Vega:OTTHUMG00000033024 +10288 LILRB2 MIM:604815|HGNC:HGNC:6606|Ensembl:ENSG00000131042|Vega:OTTHUMG00000064896 +10289 EIF1B HGNC:HGNC:30792|Ensembl:ENSG00000114784|Vega:OTTHUMG00000131388 +10290 SPEG MIM:615950|HGNC:HGNC:16901|Ensembl:ENSG00000072195|Vega:OTTHUMG00000058925 +10291 SF3A1 MIM:605595|HGNC:HGNC:10765|Ensembl:ENSG00000099995|Vega:OTTHUMG00000151005 +10293 TRAIP MIM:605958|HGNC:HGNC:30764|Ensembl:ENSG00000183763|Vega:OTTHUMG00000158269 +10294 DNAJA2 MIM:611322|HGNC:HGNC:14884|Ensembl:ENSG00000069345|Vega:OTTHUMG00000133104 +10295 BCKDK MIM:614901|HGNC:HGNC:16902|Ensembl:ENSG00000103507|Vega:OTTHUMG00000047356 +10296 MAEA MIM:606801|HGNC:HGNC:13731|Ensembl:ENSG00000090316|Vega:OTTHUMG00000160169 +10297 APC2 MIM:612034|HGNC:HGNC:24036|Ensembl:ENSG00000115266|Vega:OTTHUMG00000180059 +10298 PAK4 MIM:605451|HGNC:HGNC:16059|Ensembl:ENSG00000130669|Vega:OTTHUMG00000182800 +10299 MARCH6 MIM:613297|HGNC:HGNC:30550|Ensembl:ENSG00000145495|Vega:OTTHUMG00000162027 +10300 KATNB1 MIM:602703|HGNC:HGNC:6217|Ensembl:ENSG00000140854|Vega:OTTHUMG00000133467 +10301 DLEU1 MIM:605765|HGNC:HGNC:13747|Ensembl:ENSG00000176124|Vega:OTTHUMG00000016934 +10302 SNAPC5 MIM:605979|HGNC:HGNC:15484|Ensembl:ENSG00000174446|Vega:OTTHUMG00000133195 +10305 MMDK MIM:156232 +10306 CTPP MIM:116600 +10307 APBB3 MIM:602711|HGNC:HGNC:20708|Ensembl:ENSG00000113108|Vega:OTTHUMG00000191657 +10308 ZNF267 MIM:604752|HGNC:HGNC:13060|Ensembl:ENSG00000185947|Vega:OTTHUMG00000176535 +10309 CCNO MIM:607752|HGNC:HGNC:18576|Ensembl:ENSG00000152669|Vega:OTTHUMG00000162598 +10311 DSCR3 MIM:605298|HGNC:HGNC:3044|Ensembl:ENSG00000157538|Vega:OTTHUMG00000086659 +10312 TCIRG1 MIM:604592|HGNC:HGNC:11647|Ensembl:ENSG00000110719|Vega:OTTHUMG00000167358 +10313 RTN3 MIM:604249|HGNC:HGNC:10469|Ensembl:ENSG00000133318|Vega:OTTHUMG00000168056 +10314 LANCL1 MIM:604155|HGNC:HGNC:6508|Ensembl:ENSG00000115365|Vega:OTTHUMG00000132991 +10316 NMUR1 MIM:604153|HGNC:HGNC:4518|Ensembl:ENSG00000171596|Vega:OTTHUMG00000133225 +10317 B3GALT5 MIM:604066|HGNC:HGNC:920|Ensembl:ENSG00000183778|Vega:OTTHUMG00000086725 +10318 TNIP1 MIM:607714|HGNC:HGNC:16903|Ensembl:ENSG00000145901|Vega:OTTHUMG00000163722 +10319 LAMC3 MIM:604349|HGNC:HGNC:6494|Ensembl:ENSG00000050555|Vega:OTTHUMG00000020819 +10320 IKZF1 MIM:603023|HGNC:HGNC:13176|Ensembl:ENSG00000185811|Vega:OTTHUMG00000155907 +10321 CRISP3 HGNC:HGNC:16904|Ensembl:ENSG00000096006|Vega:OTTHUMG00000014823 +10322 SMYD5 HGNC:HGNC:16258|Ensembl:ENSG00000135632|Vega:OTTHUMG00000150482 +10324 KLHL41 MIM:607701|HGNC:HGNC:16905|Ensembl:ENSG00000239474|Vega:OTTHUMG00000132205 +10325 RRAGB MIM:300725|HGNC:HGNC:19901|Ensembl:ENSG00000083750|Vega:OTTHUMG00000021662 +10326 SIRPB1 MIM:603889|HGNC:HGNC:15928|Ensembl:ENSG00000101307|Vega:OTTHUMG00000031676 +10327 AKR1A1 MIM:103830|HGNC:HGNC:380|Ensembl:ENSG00000117448|Vega:OTTHUMG00000007740 +10328 EMC8 MIM:604886|HGNC:HGNC:7864|Ensembl:ENSG00000131148|Vega:OTTHUMG00000137647 +10329 TMEM5 MIM:605862|HGNC:HGNC:13530|Ensembl:ENSG00000118600|Vega:OTTHUMG00000168730 +10330 CNPY2 MIM:605861|HGNC:HGNC:13529|Ensembl:ENSG00000257727|Vega:OTTHUMG00000170330 +10331 B3GNT3 MIM:605863|HGNC:HGNC:13528|Ensembl:ENSG00000179913|Vega:OTTHUMG00000183490 +10332 CLEC4M MIM:605872|HGNC:HGNC:13523|Ensembl:ENSG00000104938|Vega:OTTHUMG00000182432 +10333 TLR6 MIM:605403|HGNC:HGNC:16711|Ensembl:ENSG00000174130|Vega:OTTHUMG00000128579 +10335 MRVI1 MIM:604673|HGNC:HGNC:7237|Ensembl:ENSG00000072952|Vega:OTTHUMG00000165773 +10336 PCGF3 MIM:617543|HGNC:HGNC:10066|Ensembl:ENSG00000185619|Vega:OTTHUMG00000119000 +10337 HIST1H4PS1 HGNC:HGNC:4786 +10338 HIST1H1PS2 HGNC:HGNC:4770 +10340 HIST1H2BPS2 HGNC:HGNC:4754 +10341 HIST1H2APS5 HGNC:HGNC:4728 +10342 TFG MIM:602498|HGNC:HGNC:11758|Ensembl:ENSG00000114354|Vega:OTTHUMG00000159085 +10343 PKDREJ MIM:604670|HGNC:HGNC:9015|Ensembl:ENSG00000130943|Vega:OTTHUMG00000150493 +10344 CCL26 MIM:604697|HGNC:HGNC:10625|Ensembl:ENSG00000006606|Vega:OTTHUMG00000130403 +10345 TRDN MIM:603283|HGNC:HGNC:12261|Ensembl:ENSG00000186439|Vega:OTTHUMG00000015497 +10346 TRIM22 MIM:606559|HGNC:HGNC:16379|Ensembl:ENSG00000132274|Vega:OTTHUMG00000066904 +10347 ABCA7 MIM:605414|HGNC:HGNC:37|Ensembl:ENSG00000064687|Vega:OTTHUMG00000167547 +10349 ABCA10 MIM:612508|HGNC:HGNC:30|Ensembl:ENSG00000154263|Vega:OTTHUMG00000164716 +10350 ABCA9 MIM:612507|HGNC:HGNC:39|Ensembl:ENSG00000154258|Vega:OTTHUMG00000140371 +10351 ABCA8 MIM:612505|HGNC:HGNC:38|Ensembl:ENSG00000141338|Vega:OTTHUMG00000180192 +10352 WARS2 MIM:604733|HGNC:HGNC:12730|Ensembl:ENSG00000116874|Vega:OTTHUMG00000012335 +10354 HMGB1P5 HGNC:HGNC:4997 +10355 HMGB1P4 HGNC:HGNC:4996 +10356 HMGB1P3 HGNC:HGNC:4995 +10357 HMGB1P1 HGNC:HGNC:4993 +10360 NPM3 MIM:606456|HGNC:HGNC:7931|Ensembl:ENSG00000107833|Vega:OTTHUMG00000018942 +10361 NPM2 MIM:608073|HGNC:HGNC:7930|Ensembl:ENSG00000158806|Vega:OTTHUMG00000131129 +10362 HMG20B MIM:605535|HGNC:HGNC:5002|Ensembl:ENSG00000064961|Vega:OTTHUMG00000150437 +10363 HMG20A MIM:605534|HGNC:HGNC:5001|Ensembl:ENSG00000140382|Vega:OTTHUMG00000143729 +10365 KLF2 MIM:602016|HGNC:HGNC:6347|Ensembl:ENSG00000127528|Vega:OTTHUMG00000182330 +10367 MICU1 MIM:605084|HGNC:HGNC:1530|Ensembl:ENSG00000107745|Vega:OTTHUMG00000018437 +10368 CACNG3 MIM:606403|HGNC:HGNC:1407|Ensembl:ENSG00000006116|Vega:OTTHUMG00000131651 +10369 CACNG2 MIM:602911|HGNC:HGNC:1406|Ensembl:ENSG00000166862|Vega:OTTHUMG00000030612 +10370 CITED2 MIM:602937|HGNC:HGNC:1987|Ensembl:ENSG00000164442|Vega:OTTHUMG00000015691 +10371 SEMA3A MIM:603961|HGNC:HGNC:10723|Ensembl:ENSG00000075213|Vega:OTTHUMG00000023443 +10376 TUBA1B MIM:602530|HGNC:HGNC:18809|Ensembl:ENSG00000123416|Vega:OTTHUMG00000170410 +10379 IRF9 MIM:147574|HGNC:HGNC:6131|Ensembl:ENSG00000213928|Vega:OTTHUMG00000028799 +10380 BPNT1 MIM:604053|HGNC:HGNC:1096|Ensembl:ENSG00000162813|Vega:OTTHUMG00000037435 +10381 TUBB3 MIM:602661|HGNC:HGNC:20772|Ensembl:ENSG00000258947|Vega:OTTHUMG00000138985 +10382 TUBB4A MIM:602662|HGNC:HGNC:20774|Ensembl:ENSG00000104833|Vega:OTTHUMG00000181829 +10383 TUBB4B MIM:602660|HGNC:HGNC:20771|Ensembl:ENSG00000188229|Vega:OTTHUMG00000131783 +10384 BTN3A3 MIM:613595|HGNC:HGNC:1140|Ensembl:ENSG00000111801|Vega:OTTHUMG00000014451 +10385 BTN2A2 MIM:613591|HGNC:HGNC:1137|Ensembl:ENSG00000124508|Vega:OTTHUMG00000014452 +10386 MHW1 MIM:603663 +10388 SYCP2 MIM:604105|HGNC:HGNC:11490|Ensembl:ENSG00000196074|Vega:OTTHUMG00000032872 +10389 SCML2 MIM:300208|HGNC:HGNC:10581|Ensembl:ENSG00000102098|Vega:OTTHUMG00000021212 +10390 CEPT1 MIM:616751|HGNC:HGNC:24289|Ensembl:ENSG00000134255|Vega:OTTHUMG00000012357 +10391 CORO2B MIM:605002|HGNC:HGNC:2256|Ensembl:ENSG00000103647|Vega:OTTHUMG00000133288 +10392 NOD1 MIM:605980|HGNC:HGNC:16390|Ensembl:ENSG00000106100|Vega:OTTHUMG00000023923 +10393 ANAPC10 MIM:613745|HGNC:HGNC:24077|Ensembl:ENSG00000164162|Vega:OTTHUMG00000161477 +10394 PRG3 MIM:606814|HGNC:HGNC:9363|Ensembl:ENSG00000156575|Vega:OTTHUMG00000167026 +10395 DLC1 MIM:604258|HGNC:HGNC:2897|Ensembl:ENSG00000164741|Vega:OTTHUMG00000090825 +10396 ATP8A1 MIM:609542|HGNC:HGNC:13531|Ensembl:ENSG00000124406|Vega:OTTHUMG00000099403 +10397 NDRG1 MIM:605262|HGNC:HGNC:7679|Ensembl:ENSG00000104419|Vega:OTTHUMG00000164441 +10398 MYL9 MIM:609905|HGNC:HGNC:15754|Ensembl:ENSG00000101335|Vega:OTTHUMG00000032387 +10399 RACK1 MIM:176981|HGNC:HGNC:4399|Ensembl:ENSG00000204628|Vega:OTTHUMG00000163380 +10400 PEMT MIM:602391|HGNC:HGNC:8830|Ensembl:ENSG00000133027|Vega:OTTHUMG00000059290 +10401 PIAS3 MIM:605987|HGNC:HGNC:16861|Ensembl:ENSG00000131788|Vega:OTTHUMG00000013750 +10402 ST3GAL6 MIM:607156|HGNC:HGNC:18080|Ensembl:ENSG00000064225|Vega:OTTHUMG00000159047 +10403 NDC80 MIM:607272|HGNC:HGNC:16909|Ensembl:ENSG00000080986|Vega:OTTHUMG00000131483 +10404 CPQ HGNC:HGNC:16910|Ensembl:ENSG00000104324|Vega:OTTHUMG00000164690 +10406 WFDC2 MIM:617548|HGNC:HGNC:15939|Ensembl:ENSG00000101443|Vega:OTTHUMG00000032594 +10407 SPAG11B MIM:606560|HGNC:HGNC:14534|Ensembl:ENSG00000164871|Vega:OTTHUMG00000129219 +10408 MYCNOS MIM:605374|HGNC:HGNC:16911|Ensembl:ENSG00000233718 +10409 BASP1 MIM:605940|HGNC:HGNC:957|Ensembl:ENSG00000176788|Vega:OTTHUMG00000131061 +10410 IFITM3 MIM:605579|HGNC:HGNC:5414|Ensembl:ENSG00000142089|Vega:OTTHUMG00000165542 +10411 RAPGEF3 MIM:606057|HGNC:HGNC:16629|Ensembl:ENSG00000079337|Vega:OTTHUMG00000133667 +10412 NSA2 MIM:612497|HGNC:HGNC:30728|Ensembl:ENSG00000164346|Vega:OTTHUMG00000131273 +10413 YAP1 MIM:606608|HGNC:HGNC:16262|Ensembl:ENSG00000137693|Vega:OTTHUMG00000167322 +10415 SNAI1P1 HGNC:HGNC:11129 +10417 SPON2 MIM:605918|HGNC:HGNC:11253|Ensembl:ENSG00000159674|Vega:OTTHUMG00000089002 +10418 SPON1 MIM:604989|HGNC:HGNC:11252|Ensembl:ENSG00000262655|Vega:OTTHUMG00000181576 +10419 PRMT5 MIM:604045|HGNC:HGNC:10894|Ensembl:ENSG00000100462|Vega:OTTHUMG00000028709 +10420 TESK2 MIM:604746|HGNC:HGNC:11732|Ensembl:ENSG00000070759|Vega:OTTHUMG00000007680 +10421 CD2BP2 MIM:604470|HGNC:HGNC:1656|Ensembl:ENSG00000169217|Vega:OTTHUMG00000132397 +10422 UBAC1 MIM:608129|HGNC:HGNC:30221|Ensembl:ENSG00000130560|Vega:OTTHUMG00000020920 +10423 CDIPT MIM:605893|HGNC:HGNC:1769|Ensembl:ENSG00000103502|Vega:OTTHUMG00000177144 +10424 PGRMC2 MIM:607735|HGNC:HGNC:16089|Ensembl:ENSG00000164040|Vega:OTTHUMG00000133342 +10425 ARIH2 MIM:605615|HGNC:HGNC:690|Ensembl:ENSG00000177479|Vega:OTTHUMG00000133547 +10426 TUBGCP3 HGNC:HGNC:18598|Ensembl:ENSG00000126216|Vega:OTTHUMG00000017367 +10427 SEC24B MIM:607184|HGNC:HGNC:10704|Ensembl:ENSG00000138802|Vega:OTTHUMG00000161372 +10428 CFDP1 MIM:608108|HGNC:HGNC:1873|Ensembl:ENSG00000153774|Vega:OTTHUMG00000137615 +10430 TMEM147 MIM:613585|HGNC:HGNC:30414|Ensembl:ENSG00000105677|Vega:OTTHUMG00000048105 +10432 RBM14 MIM:612409|HGNC:HGNC:14219|Ensembl:ENSG00000239306|Vega:OTTHUMG00000140380 +10434 LYPLA1 MIM:605599|HGNC:HGNC:6737|Ensembl:ENSG00000120992|Vega:OTTHUMG00000164313 +10435 CDC42EP2 MIM:606132|HGNC:HGNC:16263|Ensembl:ENSG00000149798|Vega:OTTHUMG00000165958 +10436 EMG1 MIM:611531|HGNC:HGNC:16912|Ensembl:ENSG00000126749|Ensembl:ENSG00000268439|Vega:OTTHUMG00000168968|Vega:OTTHUMG00000188247 +10437 IFI30 MIM:604664|HGNC:HGNC:5398|Ensembl:ENSG00000216490|Vega:OTTHUMG00000183373 +10438 C1D MIM:606997|HGNC:HGNC:29911|Ensembl:ENSG00000197223|Vega:OTTHUMG00000129564 +10439 OLFM1 MIM:605366|HGNC:HGNC:17187|Ensembl:ENSG00000130558|Vega:OTTHUMG00000020897 +10440 TIMM17A MIM:605057|HGNC:HGNC:17315|Ensembl:ENSG00000134375|Vega:OTTHUMG00000035806 +10443 N4BP2L2 MIM:615788|HGNC:HGNC:26916|Ensembl:ENSG00000244754|Vega:OTTHUMG00000016700 +10444 ZER1 HGNC:HGNC:30960|Ensembl:ENSG00000160445|Vega:OTTHUMG00000020759 +10445 MCRS1 MIM:609504|HGNC:HGNC:6960|Ensembl:ENSG00000187778|Vega:OTTHUMG00000169620 +10446 LRRN2 MIM:605492|HGNC:HGNC:16914|Ensembl:ENSG00000170382|Vega:OTTHUMG00000035989 +10447 FAM3C MIM:608618|HGNC:HGNC:18664|Ensembl:ENSG00000196937|Vega:OTTHUMG00000156979 +10449 ACAA2 MIM:604770|HGNC:HGNC:83|Ensembl:ENSG00000167315|Vega:OTTHUMG00000132667 +10450 PPIE MIM:602435|HGNC:HGNC:9258|Ensembl:ENSG00000084072|Vega:OTTHUMG00000009248 +10451 VAV3 MIM:605541|HGNC:HGNC:12659|Ensembl:ENSG00000134215|Vega:OTTHUMG00000010995 +10452 TOMM40 MIM:608061|HGNC:HGNC:18001|Ensembl:ENSG00000130204|Vega:OTTHUMG00000180842 +10454 TAB1 MIM:602615|HGNC:HGNC:18157|Ensembl:ENSG00000100324|Vega:OTTHUMG00000151102 +10455 ECI2 MIM:608024|HGNC:HGNC:14601|Ensembl:ENSG00000198721|Vega:OTTHUMG00000014158 +10456 HAX1 MIM:605998|HGNC:HGNC:16915|Ensembl:ENSG00000143575|Vega:OTTHUMG00000035978 +10457 GPNMB MIM:604368|HGNC:HGNC:4462|Ensembl:ENSG00000136235|Vega:OTTHUMG00000022811 +10458 BAIAP2 MIM:605475|HGNC:HGNC:947|Ensembl:ENSG00000175866|Vega:OTTHUMG00000177698 +10459 MAD2L2 MIM:604094|HGNC:HGNC:6764|Ensembl:ENSG00000116670|Vega:OTTHUMG00000002231 +10460 TACC3 MIM:605303|HGNC:HGNC:11524|Ensembl:ENSG00000013810|Vega:OTTHUMG00000089535 +10461 MERTK MIM:604705|HGNC:HGNC:7027|Ensembl:ENSG00000153208|Vega:OTTHUMG00000131278 +10462 CLEC10A MIM:605999|HGNC:HGNC:16916|Ensembl:ENSG00000132514|Vega:OTTHUMG00000177939 +10463 SLC30A9 MIM:604604|HGNC:HGNC:1329|Ensembl:ENSG00000014824|Vega:OTTHUMG00000099387 +10464 PIBF1 MIM:607532|HGNC:HGNC:23352|Ensembl:ENSG00000083535|Vega:OTTHUMG00000017071 +10465 PPIH MIM:606095|HGNC:HGNC:14651|Ensembl:ENSG00000171960|Vega:OTTHUMG00000007520 +10466 COG5 MIM:606821|HGNC:HGNC:14857|Ensembl:ENSG00000164597|Vega:OTTHUMG00000023895 +10467 ZNHIT1 HGNC:HGNC:21688|Ensembl:ENSG00000106400|Vega:OTTHUMG00000157113 +10468 FST MIM:136470|HGNC:HGNC:3971|Ensembl:ENSG00000134363|Vega:OTTHUMG00000131183 +10469 TIMM44 MIM:605058|HGNC:HGNC:17316|Ensembl:ENSG00000104980|Vega:OTTHUMG00000182478 +10471 PFDN6 MIM:605660|HGNC:HGNC:4926|Ensembl:ENSG00000204220|Vega:OTTHUMG00000031247 +10472 ZBTB18 MIM:608433|HGNC:HGNC:13030|Ensembl:ENSG00000179456|Vega:OTTHUMG00000040013 +10473 HMGN4 HGNC:HGNC:4989|Ensembl:ENSG00000182952|Vega:OTTHUMG00000014458 +10474 TADA3 MIM:602945|HGNC:HGNC:19422|Ensembl:ENSG00000171148|Vega:OTTHUMG00000128440 +10475 TRIM38 HGNC:HGNC:10059|Ensembl:ENSG00000112343|Vega:OTTHUMG00000014414 +10476 ATP5H HGNC:HGNC:845|Ensembl:ENSG00000167863|Vega:OTTHUMG00000179219 +10477 UBE2E3 MIM:604151|HGNC:HGNC:12479|Ensembl:ENSG00000170035|Vega:OTTHUMG00000132585 +10478 SLC25A17 MIM:606795|HGNC:HGNC:10987|Ensembl:ENSG00000100372|Vega:OTTHUMG00000151139 +10479 SLC9A6 MIM:300231|HGNC:HGNC:11079|Ensembl:ENSG00000198689|Vega:OTTHUMG00000022498 +10480 EIF3M MIM:609641|HGNC:HGNC:24460|Ensembl:ENSG00000149100|Vega:OTTHUMG00000166258 +10481 HOXB13 MIM:604607|HGNC:HGNC:5112|Ensembl:ENSG00000159184|Vega:OTTHUMG00000159900 +10482 NXF1 MIM:602647|HGNC:HGNC:8071|Ensembl:ENSG00000162231|Vega:OTTHUMG00000167612 +10483 SEC23B MIM:610512|HGNC:HGNC:10702|Ensembl:ENSG00000101310|Vega:OTTHUMG00000031976 +10484 SEC23A MIM:610511|HGNC:HGNC:10701|Ensembl:ENSG00000100934|Vega:OTTHUMG00000028812 +10485 C1orf61 HGNC:HGNC:30780|Ensembl:ENSG00000125462|Vega:OTTHUMG00000031022 +10486 CAP2 HGNC:HGNC:20039|Ensembl:ENSG00000112186|Vega:OTTHUMG00000014311 +10487 CAP1 HGNC:HGNC:20040|Ensembl:ENSG00000131236|Vega:OTTHUMG00000004493 +10488 CREB3 MIM:606443|HGNC:HGNC:2347|Ensembl:ENSG00000107175|Vega:OTTHUMG00000019872 +10489 LRRC41 HGNC:HGNC:16917|Ensembl:ENSG00000132128|Vega:OTTHUMG00000007810 +10490 VTI1B MIM:603207|HGNC:HGNC:17793|Ensembl:ENSG00000100568|Vega:OTTHUMG00000171251 +10491 CRTAP MIM:605497|HGNC:HGNC:2379|Ensembl:ENSG00000170275|Vega:OTTHUMG00000130746 +10492 SYNCRIP MIM:616686|HGNC:HGNC:16918|Ensembl:ENSG00000135316|Vega:OTTHUMG00000015141 +10493 VAT1 MIM:604631|HGNC:HGNC:16919|Ensembl:ENSG00000108828|Vega:OTTHUMG00000180816 +10494 STK25 MIM:602255|HGNC:HGNC:11404|Ensembl:ENSG00000115694|Vega:OTTHUMG00000133408 +10495 ENOX2 MIM:300282|HGNC:HGNC:2259|Ensembl:ENSG00000165675|Vega:OTTHUMG00000022401 +10497 UNC13B MIM:605836|HGNC:HGNC:12566|Ensembl:ENSG00000198722|Vega:OTTHUMG00000019856 +10498 CARM1 MIM:603934|HGNC:HGNC:23393|Ensembl:ENSG00000142453|Vega:OTTHUMG00000180699 +10499 NCOA2 MIM:601993|HGNC:HGNC:7669|Ensembl:ENSG00000140396|Vega:OTTHUMG00000164671 +10500 SEMA6C MIM:609294|HGNC:HGNC:10740|Ensembl:ENSG00000143434|Vega:OTTHUMG00000012261 +10501 SEMA6B MIM:608873|HGNC:HGNC:10739|Ensembl:ENSG00000167680|Vega:OTTHUMG00000182011 +10505 SEMA4F MIM:603706|HGNC:HGNC:10734|Ensembl:ENSG00000135622|Vega:OTTHUMG00000129952 +10507 SEMA4D MIM:601866|HGNC:HGNC:10732|Ensembl:ENSG00000187764|Vega:OTTHUMG00000020185 +10509 SEMA4B MIM:617029|HGNC:HGNC:10730|Ensembl:ENSG00000185033|Vega:OTTHUMG00000172096 +10512 SEMA3C MIM:602645|HGNC:HGNC:10725|Ensembl:ENSG00000075223|Vega:OTTHUMG00000023447 +10513 APPBP2 MIM:605324|HGNC:HGNC:622|Ensembl:ENSG00000062725|Vega:OTTHUMG00000180048 +10514 MYBBP1A MIM:604885|HGNC:HGNC:7546|Ensembl:ENSG00000132382|Vega:OTTHUMG00000090747 +10516 FBLN5 MIM:604580|HGNC:HGNC:3602|Ensembl:ENSG00000140092|Vega:OTTHUMG00000171122 +10517 FBXW10 MIM:611679|HGNC:HGNC:1211|Ensembl:ENSG00000171931|Vega:OTTHUMG00000059048 +10518 CIB2 MIM:605564|HGNC:HGNC:24579|Ensembl:ENSG00000136425|Vega:OTTHUMG00000143731 +10519 CIB1 MIM:602293|HGNC:HGNC:16920|Ensembl:ENSG00000185043|Vega:OTTHUMG00000149808 +10520 ZNF211 MIM:601856|HGNC:HGNC:13003|Ensembl:ENSG00000121417|Vega:OTTHUMG00000168012 +10521 DDX17 MIM:608469|HGNC:HGNC:2740|Ensembl:ENSG00000100201|Vega:OTTHUMG00000151136 +10522 DEAF1 MIM:602635|HGNC:HGNC:14677|Ensembl:ENSG00000177030|Vega:OTTHUMG00000165363 +10523 CHERP HGNC:HGNC:16930|Ensembl:ENSG00000085872|Vega:OTTHUMG00000169304 +10524 KAT5 MIM:601409|HGNC:HGNC:5275|Ensembl:ENSG00000172977|Vega:OTTHUMG00000166617 +10525 HYOU1 MIM:601746|HGNC:HGNC:16931|Ensembl:ENSG00000149428|Vega:OTTHUMG00000166354 +10526 IPO8 MIM:605600|HGNC:HGNC:9853|Ensembl:ENSG00000133704|Vega:OTTHUMG00000169172 +10527 IPO7 MIM:605586|HGNC:HGNC:9852|Ensembl:ENSG00000205339|Vega:OTTHUMG00000165753 +10528 NOP56 MIM:614154|HGNC:HGNC:15911|Ensembl:ENSG00000101361|Vega:OTTHUMG00000031703 +10529 NEBL MIM:605491|HGNC:HGNC:16932|Ensembl:ENSG00000078114|Vega:OTTHUMG00000017788 +10531 PITRM1 HGNC:HGNC:17663|Ensembl:ENSG00000107959|Vega:OTTHUMG00000017557 +10533 ATG7 MIM:608760|HGNC:HGNC:16935|Ensembl:ENSG00000197548|Vega:OTTHUMG00000129740 +10534 SSSCA1 MIM:606044|HGNC:HGNC:11328|Ensembl:ENSG00000173465|Vega:OTTHUMG00000166388 +10535 RNASEH2A MIM:606034|HGNC:HGNC:18518|Ensembl:ENSG00000104889|Vega:OTTHUMG00000180481 +10536 P3H3 MIM:610342|HGNC:HGNC:19318|Ensembl:ENSG00000110811|Vega:OTTHUMG00000168516 +10537 UBD MIM:606050|HGNC:HGNC:18795|Ensembl:ENSG00000213886|Vega:OTTHUMG00000031289 +10538 BATF MIM:612476|HGNC:HGNC:958|Ensembl:ENSG00000156127|Vega:OTTHUMG00000171486 +10539 GLRX3 MIM:612754|HGNC:HGNC:15987|Ensembl:ENSG00000108010|Vega:OTTHUMG00000019267 +10540 DCTN2 MIM:607376|HGNC:HGNC:2712|Ensembl:ENSG00000175203|Vega:OTTHUMG00000170124 +10541 ANP32B HGNC:HGNC:16677|Ensembl:ENSG00000136938|Vega:OTTHUMG00000020338 +10542 LAMTOR5 MIM:608521|HGNC:HGNC:17955|Ensembl:ENSG00000134248|Vega:OTTHUMG00000011568 +10544 PROCR MIM:600646|HGNC:HGNC:9452|Ensembl:ENSG00000101000|Vega:OTTHUMG00000032323 +10547 PSORS4 MIM:603935|HGNC:HGNC:17275 +10548 TM9SF1 HGNC:HGNC:11864|Ensembl:ENSG00000100926|Vega:OTTHUMG00000029322 +10549 PRDX4 MIM:300927|HGNC:HGNC:17169|Ensembl:ENSG00000123131|Vega:OTTHUMG00000021253 +10550 ARL6IP5 MIM:605709|HGNC:HGNC:16937|Ensembl:ENSG00000144746|Vega:OTTHUMG00000158773 +10551 AGR2 MIM:606358|HGNC:HGNC:328|Ensembl:ENSG00000106541|Vega:OTTHUMG00000023446 +10552 ARPC1A MIM:604220|HGNC:HGNC:703|Ensembl:ENSG00000241685|Vega:OTTHUMG00000154553 +10553 HTATIP2 MIM:605628|HGNC:HGNC:16637|Ensembl:ENSG00000109854|Vega:OTTHUMG00000166015 +10554 AGPAT1 MIM:603099|HGNC:HGNC:324|Ensembl:ENSG00000204310|Vega:OTTHUMG00000031210 +10555 AGPAT2 MIM:603100|HGNC:HGNC:325|Ensembl:ENSG00000169692|Vega:OTTHUMG00000020936 +10556 RPP30 MIM:606115|HGNC:HGNC:17688|Ensembl:ENSG00000148688|Vega:OTTHUMG00000018733 +10557 RPP38 MIM:606116|HGNC:HGNC:30329|Ensembl:ENSG00000152464|Vega:OTTHUMG00000017728 +10558 SPTLC1 MIM:605712|HGNC:HGNC:11277|Ensembl:ENSG00000090054|Vega:OTTHUMG00000021047 +10559 SLC35A1 MIM:605634|HGNC:HGNC:11021|Ensembl:ENSG00000164414|Vega:OTTHUMG00000015177 +10560 SLC19A2 MIM:603941|HGNC:HGNC:10938|Ensembl:ENSG00000117479|Vega:OTTHUMG00000035452 +10561 IFI44 MIM:610468|HGNC:HGNC:16938|Ensembl:ENSG00000137965|Vega:OTTHUMG00000009723 +10562 OLFM4 MIM:614061|HGNC:HGNC:17190|Ensembl:ENSG00000102837|Vega:OTTHUMG00000016981 +10563 CXCL13 MIM:605149|HGNC:HGNC:10639|Ensembl:ENSG00000156234|Vega:OTTHUMG00000130201 +10564 ARFGEF2 MIM:605371|HGNC:HGNC:15853|Ensembl:ENSG00000124198|Vega:OTTHUMG00000032687 +10565 ARFGEF1 MIM:604141|HGNC:HGNC:15772|Ensembl:ENSG00000066777|Vega:OTTHUMG00000164626 +10566 AKAP3 MIM:604689|HGNC:HGNC:373|Ensembl:ENSG00000111254|Vega:OTTHUMG00000168226 +10567 RABAC1 MIM:604925|HGNC:HGNC:9794|Ensembl:ENSG00000105404|Vega:OTTHUMG00000182737 +10568 SLC34A2 MIM:604217|HGNC:HGNC:11020|Ensembl:ENSG00000157765|Vega:OTTHUMG00000097757 +10569 SLU7 MIM:605974|HGNC:HGNC:16939|Ensembl:ENSG00000164609|Vega:OTTHUMG00000130324 +10570 DPYSL4 MIM:608407|HGNC:HGNC:3016|Ensembl:ENSG00000151640|Vega:OTTHUMG00000019283 +10572 SIVA1 MIM:605567|HGNC:HGNC:17712|Ensembl:ENSG00000184990|Vega:OTTHUMG00000170819 +10573 MRPL28 MIM:604853|HGNC:HGNC:14484|Ensembl:ENSG00000086504|Vega:OTTHUMG00000047994 +10574 CCT7 MIM:605140|HGNC:HGNC:1622|Ensembl:ENSG00000135624|Vega:OTTHUMG00000152765 +10575 CCT4 MIM:605142|HGNC:HGNC:1617|Ensembl:ENSG00000115484|Vega:OTTHUMG00000152166 +10576 CCT2 MIM:605139|HGNC:HGNC:1615|Ensembl:ENSG00000166226|Vega:OTTHUMG00000169383 +10577 NPC2 MIM:601015|HGNC:HGNC:14537|Ensembl:ENSG00000119655|Vega:OTTHUMG00000171212 +10578 GNLY MIM:188855|HGNC:HGNC:4414|Ensembl:ENSG00000115523|Vega:OTTHUMG00000130179 +10579 TACC2 MIM:605302|HGNC:HGNC:11523|Ensembl:ENSG00000138162|Vega:OTTHUMG00000019181 +10580 SORBS1 MIM:605264|HGNC:HGNC:14565|Ensembl:ENSG00000095637|Vega:OTTHUMG00000018812 +10581 IFITM2 MIM:605578|HGNC:HGNC:5413|Ensembl:ENSG00000185201|Vega:OTTHUMG00000165357 +10584 COLEC10 MIM:607620|HGNC:HGNC:2220|Ensembl:ENSG00000184374|Vega:OTTHUMG00000164971 +10585 POMT1 MIM:607423|HGNC:HGNC:9202|Ensembl:ENSG00000130714|Vega:OTTHUMG00000020826 +10586 MAB21L2 MIM:604357|HGNC:HGNC:6758|Ensembl:ENSG00000181541|Vega:OTTHUMG00000161442 +10587 TXNRD2 MIM:606448|HGNC:HGNC:18155|Ensembl:ENSG00000184470|Vega:OTTHUMG00000149975 +10588 MTHFS MIM:604197|HGNC:HGNC:7437|Ensembl:ENSG00000136371|Vega:OTTHUMG00000144174 +10589 DRAP1 MIM:602289|HGNC:HGNC:3019|Ensembl:ENSG00000175550|Vega:OTTHUMG00000166723 +10590 SCGN MIM:609202|HGNC:HGNC:16941|Ensembl:ENSG00000079689|Vega:OTTHUMG00000014409 +10591 DNPH1 HGNC:HGNC:21218|Ensembl:ENSG00000112667|Vega:OTTHUMG00000014724 +10592 SMC2 MIM:605576|HGNC:HGNC:14011|Ensembl:ENSG00000136824|Vega:OTTHUMG00000020401 +10594 PRPF8 MIM:607300|HGNC:HGNC:17340|Ensembl:ENSG00000174231|Vega:OTTHUMG00000090553 +10595 ERN2 MIM:604034|HGNC:HGNC:16942|Ensembl:ENSG00000134398|Vega:OTTHUMG00000177020 +10597 TRAPPC2B HGNC:HGNC:10710|Ensembl:ENSG00000256060|Vega:OTTHUMG00000183279 +10598 AHSA1 MIM:608466|HGNC:HGNC:1189|Ensembl:ENSG00000100591|Vega:OTTHUMG00000171539 +10599 SLCO1B1 MIM:604843|HGNC:HGNC:10959|Ensembl:ENSG00000134538|Vega:OTTHUMG00000169047 +10600 USP16 MIM:604735|HGNC:HGNC:12614|Ensembl:ENSG00000156256|Vega:OTTHUMG00000078802 +10602 CDC42EP3 MIM:606133|HGNC:HGNC:16943|Ensembl:ENSG00000163171|Vega:OTTHUMG00000100971 +10603 SH2B2 MIM:605300|HGNC:HGNC:17381|Ensembl:ENSG00000160999|Vega:OTTHUMG00000150652 +10605 PAIP1 MIM:605184|HGNC:HGNC:16945|Ensembl:ENSG00000172239|Vega:OTTHUMG00000096960 +10606 PAICS MIM:172439|HGNC:HGNC:8587|Ensembl:ENSG00000128050|Vega:OTTHUMG00000160957 +10607 TBL3 MIM:605915|HGNC:HGNC:11587|Ensembl:ENSG00000183751|Vega:OTTHUMG00000128710 +10608 MXD4 HGNC:HGNC:13906|Ensembl:ENSG00000123933|Vega:OTTHUMG00000090243 +10609 P3H4 MIM:617419|HGNC:HGNC:16946|Ensembl:ENSG00000141696|Vega:OTTHUMG00000133501 +10610 ST6GALNAC2 MIM:610137|HGNC:HGNC:10867|Ensembl:ENSG00000070731|Vega:OTTHUMG00000191877 +10611 PDLIM5 MIM:605904|HGNC:HGNC:17468|Ensembl:ENSG00000163110|Vega:OTTHUMG00000130973 +10612 TRIM3 MIM:605493|HGNC:HGNC:10064|Ensembl:ENSG00000110171|Vega:OTTHUMG00000133405 +10613 ERLIN1 MIM:611604|HGNC:HGNC:16947|Ensembl:ENSG00000107566|Vega:OTTHUMG00000018900 +10614 HEXIM1 MIM:607328|HGNC:HGNC:24953|Ensembl:ENSG00000186834|Vega:OTTHUMG00000180112 +10615 SPAG5 MIM:615562|HGNC:HGNC:13452|Ensembl:ENSG00000076382|Vega:OTTHUMG00000166586 +10616 RBCK1 MIM:610924|HGNC:HGNC:15864|Ensembl:ENSG00000125826|Vega:OTTHUMG00000031634 +10617 STAMBP MIM:606247|HGNC:HGNC:16950|Ensembl:ENSG00000124356|Vega:OTTHUMG00000129817 +10618 TGOLN2 MIM:603062|HGNC:HGNC:15450|Ensembl:ENSG00000152291|Vega:OTTHUMG00000153017 +10620 ARID3B MIM:612457|HGNC:HGNC:14350|Ensembl:ENSG00000179361|Vega:OTTHUMG00000141321 +10621 POLR3F MIM:617455|HGNC:HGNC:15763|Ensembl:ENSG00000132664|Vega:OTTHUMG00000031971 +10622 POLR3G MIM:617456|HGNC:HGNC:30075|Ensembl:ENSG00000113356|Vega:OTTHUMG00000162809 +10623 POLR3C MIM:617454|HGNC:HGNC:30076|Ensembl:ENSG00000186141|Vega:OTTHUMG00000013753 +10625 IVNS1ABP MIM:609209|HGNC:HGNC:16951|Ensembl:ENSG00000116679|Vega:OTTHUMG00000035384 +10626 TRIM16 MIM:609505|HGNC:HGNC:17241|Ensembl:ENSG00000221926|Vega:OTTHUMG00000059067 +10627 MYL12A HGNC:HGNC:16701|Ensembl:ENSG00000101608|Vega:OTTHUMG00000131509 +10628 TXNIP MIM:606599|HGNC:HGNC:16952|Ensembl:ENSG00000265972|Vega:OTTHUMG00000013755 +10629 TAF6L MIM:602946|HGNC:HGNC:17305|Ensembl:ENSG00000162227|Vega:OTTHUMG00000167610 +10630 PDPN MIM:608863|HGNC:HGNC:29602|Ensembl:ENSG00000162493|Vega:OTTHUMG00000007912 +10631 POSTN MIM:608777|HGNC:HGNC:16953|Ensembl:ENSG00000133110|Vega:OTTHUMG00000016751 +10632 ATP5L MIM:617473|HGNC:HGNC:14247|Ensembl:ENSG00000167283|Vega:OTTHUMG00000166336 +10633 RASL10A MIM:602220|HGNC:HGNC:16954|Ensembl:ENSG00000100276|Vega:OTTHUMG00000151106 +10634 GAS2L1 MIM:602128|HGNC:HGNC:16955|Ensembl:ENSG00000185340|Vega:OTTHUMG00000151108 +10635 RAD51AP1 MIM:603070|HGNC:HGNC:16956|Ensembl:ENSG00000111247|Vega:OTTHUMG00000168125 +10636 RGS14 MIM:602513|HGNC:HGNC:9996|Ensembl:ENSG00000169220|Vega:OTTHUMG00000163324 +10637 LEFTY1 MIM:603037|HGNC:HGNC:6552|Ensembl:ENSG00000243709|Vega:OTTHUMG00000037443 +10638 SPHAR HGNC:HGNC:16957|Ensembl:ENSG00000213029|Vega:OTTHUMG00000058947 +10639 HHCM - +10640 EXOC5 MIM:604469|HGNC:HGNC:10696|Ensembl:ENSG00000070367|Vega:OTTHUMG00000171309 +10641 NPRL2 MIM:607072|HGNC:HGNC:24969|Ensembl:ENSG00000114388|Vega:OTTHUMG00000156864 +10642 IGF2BP1 MIM:608288|HGNC:HGNC:28866|Ensembl:ENSG00000159217|Vega:OTTHUMG00000161173 +10643 IGF2BP3 MIM:608259|HGNC:HGNC:28868|Ensembl:ENSG00000136231|Vega:OTTHUMG00000128445 +10644 IGF2BP2 MIM:608289|HGNC:HGNC:28867|Ensembl:ENSG00000073792|Vega:OTTHUMG00000074025 +10645 CAMKK2 MIM:615002|HGNC:HGNC:1470|Ensembl:ENSG00000110931|Vega:OTTHUMG00000169156 +10647 SCGB1D2 MIM:615061|HGNC:HGNC:18396|Ensembl:ENSG00000124935|Vega:OTTHUMG00000167508 +10648 SCGB1D1 MIM:615060|HGNC:HGNC:18395|Ensembl:ENSG00000168515|Vega:OTTHUMG00000167505 +10650 PRELID3A MIM:616545|HGNC:HGNC:24639|Ensembl:ENSG00000141391|Vega:OTTHUMG00000131694 +10651 MTX2 MIM:608555|HGNC:HGNC:7506|Ensembl:ENSG00000128654|Vega:OTTHUMG00000132514 +10652 YKT6 MIM:606209|HGNC:HGNC:16959|Ensembl:ENSG00000106636|Vega:OTTHUMG00000129089 +10653 SPINT2 MIM:605124|HGNC:HGNC:11247|Ensembl:ENSG00000167642|Vega:OTTHUMG00000181891 +10654 PMVK MIM:607622|HGNC:HGNC:9141|Ensembl:ENSG00000163344|Vega:OTTHUMG00000037415 +10655 DMRT2 MIM:604935|HGNC:HGNC:2935|Ensembl:ENSG00000173253|Vega:OTTHUMG00000019437 +10656 KHDRBS3 MIM:610421|HGNC:HGNC:18117|Ensembl:ENSG00000131773|Vega:OTTHUMG00000164164 +10657 KHDRBS1 MIM:602489|HGNC:HGNC:18116|Ensembl:ENSG00000121774|Vega:OTTHUMG00000003921 +10658 CELF1 MIM:601074|HGNC:HGNC:2549|Ensembl:ENSG00000149187|Vega:OTTHUMG00000166526 +10659 CELF2 MIM:602538|HGNC:HGNC:2550|Ensembl:ENSG00000048740|Vega:OTTHUMG00000017668 +10660 LBX1 MIM:604255|HGNC:HGNC:16960|Ensembl:ENSG00000138136|Vega:OTTHUMG00000018927 +10661 KLF1 MIM:600599|HGNC:HGNC:6345|Ensembl:ENSG00000105610|Vega:OTTHUMG00000180536 +10663 CXCR6 MIM:605163|HGNC:HGNC:16647|Ensembl:ENSG00000172215|Vega:OTTHUMG00000133448 +10664 CTCF MIM:604167|HGNC:HGNC:13723|Ensembl:ENSG00000102974|Vega:OTTHUMG00000137539 +10665 C6orf10 HGNC:HGNC:13922|Ensembl:ENSG00000204296|Vega:OTTHUMG00000031107 +10666 CD226 MIM:605397|HGNC:HGNC:16961|Ensembl:ENSG00000150637|Vega:OTTHUMG00000132809 +10667 FARS2 MIM:611592|HGNC:HGNC:21062|Ensembl:ENSG00000145982|Vega:OTTHUMG00000014178 +10668 CGRRF1 MIM:606138|HGNC:HGNC:15528|Ensembl:ENSG00000100532|Vega:OTTHUMG00000140308 +10669 CGREF1 MIM:606137|HGNC:HGNC:16962|Ensembl:ENSG00000138028|Vega:OTTHUMG00000152009 +10670 RRAGA MIM:612194|HGNC:HGNC:16963|Ensembl:ENSG00000155876|Vega:OTTHUMG00000019621 +10671 DCTN6 MIM:612963|HGNC:HGNC:16964|Ensembl:ENSG00000104671|Vega:OTTHUMG00000163828 +10672 GNA13 MIM:604406|HGNC:HGNC:4381|Ensembl:ENSG00000120063|Vega:OTTHUMG00000179316 +10673 TNFSF13B MIM:603969|HGNC:HGNC:11929|Ensembl:ENSG00000102524|Vega:OTTHUMG00000017329 +10674 DURS1 MIM:126800|HGNC:HGNC:3063 +10675 CSPG5 MIM:606775|HGNC:HGNC:2467|Ensembl:ENSG00000114646|Vega:OTTHUMG00000133518 +10677 AVIL MIM:613397|HGNC:HGNC:14188|Ensembl:ENSG00000135407|Vega:OTTHUMG00000170461 +10678 B3GNT2 MIM:605581|HGNC:HGNC:15629|Ensembl:ENSG00000170340|Vega:OTTHUMG00000129444 +10681 GNB5 MIM:604447|HGNC:HGNC:4401|Ensembl:ENSG00000069966|Vega:OTTHUMG00000131892 +10682 EBP MIM:300205|HGNC:HGNC:3133|Ensembl:ENSG00000147155|Vega:OTTHUMG00000034482 +10683 DLL3 MIM:602768|HGNC:HGNC:2909|Ensembl:ENSG00000090932|Vega:OTTHUMG00000183067 +10686 CLDN16 MIM:603959|HGNC:HGNC:2037|Ensembl:ENSG00000113946|Vega:OTTHUMG00000156215 +10687 PNMA2 MIM:603970|HGNC:HGNC:9159|Ensembl:ENSG00000240694|Vega:OTTHUMG00000163816 +10688 CRSP5 HGNC:HGNC:2374 +10690 FUT9 MIM:606865|HGNC:HGNC:4020|Ensembl:ENSG00000172461|Vega:OTTHUMG00000015236 +10691 GMEB1 MIM:604409|HGNC:HGNC:4370|Ensembl:ENSG00000162419|Vega:OTTHUMG00000003647 +10692 RRH MIM:605224|HGNC:HGNC:10450|Ensembl:ENSG00000180245|Vega:OTTHUMG00000132045 +10693 CCT6B MIM:610730|HGNC:HGNC:1621|Ensembl:ENSG00000132141|Vega:OTTHUMG00000179770 +10694 CCT8 HGNC:HGNC:1623|Ensembl:ENSG00000156261|Vega:OTTHUMG00000044595 +10695 CNPY3 MIM:610774|HGNC:HGNC:11968|Ensembl:ENSG00000137161|Vega:OTTHUMG00000014708 +10699 CORIN MIM:605236|HGNC:HGNC:19012|Ensembl:ENSG00000145244|Vega:OTTHUMG00000099441 +10712 FAM189B HGNC:HGNC:1233|Ensembl:ENSG00000160767|Vega:OTTHUMG00000035844 +10713 USP39 MIM:611594|HGNC:HGNC:20071|Ensembl:ENSG00000168883|Vega:OTTHUMG00000153090 +10714 POLD3 MIM:611415|HGNC:HGNC:20932|Ensembl:ENSG00000077514|Vega:OTTHUMG00000165621 +10715 CERS1 MIM:606919|HGNC:HGNC:14253|Ensembl:ENSG00000223802|Vega:OTTHUMG00000183049 +10716 TBR1 MIM:604616|HGNC:HGNC:11590|Ensembl:ENSG00000136535|Vega:OTTHUMG00000153888 +10717 AP4B1 MIM:607245|HGNC:HGNC:572|Ensembl:ENSG00000134262|Vega:OTTHUMG00000011943 +10718 NRG3 MIM:605533|HGNC:HGNC:7999|Ensembl:ENSG00000185737|Vega:OTTHUMG00000018626 +10720 UGT2B11 MIM:603064|HGNC:HGNC:12545|Ensembl:ENSG00000213759|Vega:OTTHUMG00000129395 +10721 POLQ MIM:604419|HGNC:HGNC:9186|Ensembl:ENSG00000051341|Vega:OTTHUMG00000159396 +10723 SLC12A7 MIM:604879|HGNC:HGNC:10915|Ensembl:ENSG00000113504|Vega:OTTHUMG00000161931 +10724 MGEA5 MIM:604039|HGNC:HGNC:7056|Ensembl:ENSG00000198408|Vega:OTTHUMG00000018939 +10725 NFAT5 MIM:604708|HGNC:HGNC:7774|Ensembl:ENSG00000102908|Vega:OTTHUMG00000137572 +10726 NUDC MIM:610325|HGNC:HGNC:8045|Ensembl:ENSG00000090273|Vega:OTTHUMG00000004226 +10728 PTGES3 MIM:607061|HGNC:HGNC:16049|Ensembl:ENSG00000110958|Vega:OTTHUMG00000170217 +10730 YME1L1 MIM:607472|HGNC:HGNC:12843|Ensembl:ENSG00000136758|Vega:OTTHUMG00000017853 +10732 TCFL5 MIM:604745|HGNC:HGNC:11646|Ensembl:ENSG00000101190|Vega:OTTHUMG00000032939 +10733 PLK4 MIM:605031|HGNC:HGNC:11397|Ensembl:ENSG00000142731|Vega:OTTHUMG00000133301 +10734 STAG3 MIM:608489|HGNC:HGNC:11356|Ensembl:ENSG00000066923|Vega:OTTHUMG00000155183 +10735 STAG2 MIM:300826|HGNC:HGNC:11355|Ensembl:ENSG00000101972|Vega:OTTHUMG00000022725 +10736 SIX2 MIM:604994|HGNC:HGNC:10888|Ensembl:ENSG00000170577|Vega:OTTHUMG00000152421 +10737 RFPL3S MIM:605971|HGNC:HGNC:9981|Ensembl:ENSG00000205853|Vega:OTTHUMG00000030295 +10738 RFPL3 MIM:605970|HGNC:HGNC:9980|Ensembl:ENSG00000128276|Vega:OTTHUMG00000030290 +10739 RFPL2 MIM:605969|HGNC:HGNC:9979|Ensembl:ENSG00000128253|Vega:OTTHUMG00000030374 +10740 RFPL1S MIM:605972|HGNC:HGNC:9978 +10741 RBBP9 MIM:602908|HGNC:HGNC:9892|Ensembl:ENSG00000089050|Vega:OTTHUMG00000031972 +10742 RAI2 MIM:300217|HGNC:HGNC:9835|Ensembl:ENSG00000131831|Vega:OTTHUMG00000021209 +10743 RAI1 MIM:607642|HGNC:HGNC:9834|Ensembl:ENSG00000108557|Vega:OTTHUMG00000059314 +10744 PTTG2 MIM:604231|HGNC:HGNC:9691|Ensembl:ENSG00000250254|Vega:OTTHUMG00000160424 +10745 PHTF1 MIM:604950|HGNC:HGNC:8939|Ensembl:ENSG00000116793|Vega:OTTHUMG00000011800 +10746 MAP3K2 MIM:609487|HGNC:HGNC:6854|Ensembl:ENSG00000169967|Vega:OTTHUMG00000153397 +10747 MASP2 MIM:605102|HGNC:HGNC:6902|Ensembl:ENSG00000009724|Vega:OTTHUMG00000002121 +10748 KLRA1P MIM:604274|HGNC:HGNC:6372 +10749 KIF1C MIM:603060|HGNC:HGNC:6317|Ensembl:ENSG00000129250|Vega:OTTHUMG00000099451 +10750 GRAP MIM:604330|HGNC:HGNC:4562|Ensembl:ENSG00000154016|Vega:OTTHUMG00000059436 +10751 OFD1P18Y HGNC:HGNC:2589 +10752 CHL1 MIM:607416|HGNC:HGNC:1939|Ensembl:ENSG00000134121|Vega:OTTHUMG00000090601 +10753 CAPN9 MIM:606401|HGNC:HGNC:1486|Ensembl:ENSG00000135773|Vega:OTTHUMG00000037779 +10755 GIPC1 MIM:605072|HGNC:HGNC:1226|Ensembl:ENSG00000123159|Vega:OTTHUMG00000182248 +10758 TRAF3IP2 MIM:607043|HGNC:HGNC:1343|Ensembl:ENSG00000056972|Vega:OTTHUMG00000015379 +10761 PLAC1 MIM:300296|HGNC:HGNC:9044|Ensembl:ENSG00000170965|Vega:OTTHUMG00000022457 +10762 NUP50 MIM:604646|HGNC:HGNC:8065|Ensembl:ENSG00000093000|Vega:OTTHUMG00000151265 +10763 NES MIM:600915|HGNC:HGNC:7756|Ensembl:ENSG00000132688|Vega:OTTHUMG00000034299 +10765 KDM5B MIM:605393|HGNC:HGNC:18039|Ensembl:ENSG00000117139|Vega:OTTHUMG00000041401 +10766 TOB2 MIM:607396|HGNC:HGNC:11980|Ensembl:ENSG00000183864|Vega:OTTHUMG00000150970 +10767 HBS1L MIM:612450|HGNC:HGNC:4834|Ensembl:ENSG00000112339|Vega:OTTHUMG00000015626 +10768 AHCYL1 MIM:607826|HGNC:HGNC:344|Ensembl:ENSG00000168710|Vega:OTTHUMG00000011652 +10769 PLK2 MIM:607023|HGNC:HGNC:19699|Ensembl:ENSG00000145632|Vega:OTTHUMG00000097047 +10771 ZMYND11 MIM:608668|HGNC:HGNC:16966|Ensembl:ENSG00000015171|Vega:OTTHUMG00000017526 +10772 SRSF10 MIM:605221|HGNC:HGNC:16713|Ensembl:ENSG00000188529|Vega:OTTHUMG00000013893 +10773 ZBTB6 MIM:605976|HGNC:HGNC:16764|Ensembl:ENSG00000186130|Vega:OTTHUMG00000020628 +10774 DHS MIM:194380 +10775 POP4 MIM:606114|HGNC:HGNC:30081|Ensembl:ENSG00000105171|Vega:OTTHUMG00000182020 +10776 ARPP19 MIM:605487|HGNC:HGNC:16967|Ensembl:ENSG00000128989|Vega:OTTHUMG00000172677 +10777 ARPP21 MIM:605488|HGNC:HGNC:16968|Ensembl:ENSG00000172995|Vega:OTTHUMG00000130795 +10778 ZNF271P MIM:604754|HGNC:HGNC:13065|Ensembl:ENSG00000257267 +10780 ZNF234 MIM:604750|HGNC:HGNC:13027|Ensembl:ENSG00000263002|Vega:OTTHUMG00000182337 +10781 ZNF266 MIM:604751|HGNC:HGNC:13059|Ensembl:ENSG00000174652|Vega:OTTHUMG00000179945 +10782 ZNF274 MIM:605467|HGNC:HGNC:13068|Ensembl:ENSG00000171606|Vega:OTTHUMG00000183456 +10783 NEK6 MIM:604884|HGNC:HGNC:7749|Ensembl:ENSG00000119408|Vega:OTTHUMG00000020650 +10785 WDR4 MIM:605924|HGNC:HGNC:12756|Ensembl:ENSG00000160193|Vega:OTTHUMG00000086826 +10786 SLC17A3 MIM:611034|HGNC:HGNC:10931|Ensembl:ENSG00000124564|Vega:OTTHUMG00000014412 +10787 NCKAP1 MIM:604891|HGNC:HGNC:7666|Ensembl:ENSG00000061676|Vega:OTTHUMG00000132623 +10788 IQGAP2 MIM:605401|HGNC:HGNC:6111|Ensembl:ENSG00000145703|Vega:OTTHUMG00000162432 +10789 NUDCP2 HGNC:HGNC:8047 +10790 NUDCP1 HGNC:HGNC:8046 +10791 VAMP5 MIM:607029|HGNC:HGNC:12646|Ensembl:ENSG00000168899|Vega:OTTHUMG00000130169 +10793 ZNF273 MIM:604756|HGNC:HGNC:13067|Ensembl:ENSG00000198039|Vega:OTTHUMG00000149837 +10794 ZNF460 MIM:604755|HGNC:HGNC:21628|Ensembl:ENSG00000197714|Vega:OTTHUMG00000183222 +10795 ZNF268 MIM:604753|HGNC:HGNC:13061|Ensembl:ENSG00000090612|Vega:OTTHUMG00000167946 +10797 MTHFD2 MIM:604887|HGNC:HGNC:7434|Ensembl:ENSG00000065911|Vega:OTTHUMG00000129814 +10798 OR5I1 MIM:608496|HGNC:HGNC:8347|Ensembl:ENSG00000167825|Vega:OTTHUMG00000166821 +10799 RPP40 MIM:606117|HGNC:HGNC:20992|Ensembl:ENSG00000124787|Vega:OTTHUMG00000014168 +10800 CYSLTR1 MIM:300201|HGNC:HGNC:17451|Ensembl:ENSG00000173198|Vega:OTTHUMG00000021889 +10801 SEPT9 MIM:604061|HGNC:HGNC:7323|Ensembl:ENSG00000184640|Vega:OTTHUMG00000177327 +10802 SEC24A MIM:607183|HGNC:HGNC:10703|Ensembl:ENSG00000113615|Vega:OTTHUMG00000163064 +10803 CCR9 MIM:604738|HGNC:HGNC:1610|Ensembl:ENSG00000173585|Vega:OTTHUMG00000133450 +10804 GJB6 MIM:604418|HGNC:HGNC:4288|Ensembl:ENSG00000121742|Vega:OTTHUMG00000016515 +10806 SDCCAG8 MIM:613524|HGNC:HGNC:10671|Ensembl:ENSG00000054282|Vega:OTTHUMG00000039996 +10807 SDCCAG3 HGNC:HGNC:10667|Ensembl:ENSG00000165689|Vega:OTTHUMG00000020928 +10808 HSPH1 MIM:610703|HGNC:HGNC:16969|Ensembl:ENSG00000120694|Vega:OTTHUMG00000016685 +10809 STARD10 MIM:617382|HGNC:HGNC:10666|Ensembl:ENSG00000214530|Vega:OTTHUMG00000167954 +10810 WASF3 MIM:605068|HGNC:HGNC:12734|Ensembl:ENSG00000132970|Vega:OTTHUMG00000016621 +10811 NOXA1 MIM:611255|HGNC:HGNC:10668|Ensembl:ENSG00000188747|Vega:OTTHUMG00000131781 +10813 UTP14A MIM:300508|HGNC:HGNC:10665|Ensembl:ENSG00000156697|Vega:OTTHUMG00000022378 +10814 CPLX2 MIM:605033|HGNC:HGNC:2310|Ensembl:ENSG00000145920|Vega:OTTHUMG00000130665 +10815 CPLX1 MIM:605032|HGNC:HGNC:2309|Ensembl:ENSG00000168993|Vega:OTTHUMG00000160005 +10816 SPINT3 MIM:613941|HGNC:HGNC:11248|Ensembl:ENSG00000101446|Vega:OTTHUMG00000032585 +10817 FRS3 MIM:607744|HGNC:HGNC:16970|Ensembl:ENSG00000137218|Vega:OTTHUMG00000014686 +10818 FRS2 MIM:607743|HGNC:HGNC:16971|Ensembl:ENSG00000166225|Vega:OTTHUMG00000169373 +10819 OR7E14P HGNC:HGNC:8385|Ensembl:ENSG00000184669 +10820 OR7E13P HGNC:HGNC:8384 +10821 OR7E12P HGNC:HGNC:8383|Ensembl:ENSG00000189398 +10822 OR7E11P HGNC:HGNC:8382 +10823 OR7E10P HGNC:HGNC:8381 +10824 DIAPH2-AS1 MIM:300347|HGNC:HGNC:16972|Ensembl:ENSG00000236256 +10825 NEU3 MIM:604617|HGNC:HGNC:7760|Ensembl:ENSG00000162139|Vega:OTTHUMG00000165518 +10826 FAXDC2 HGNC:HGNC:1334|Ensembl:ENSG00000170271|Vega:OTTHUMG00000164141 +10827 FAM114A2 HGNC:HGNC:1333|Ensembl:ENSG00000055147|Vega:OTTHUMG00000130147 +10828 NPM1P19 HGNC:HGNC:7921 +10829 NPM1P18 HGNC:HGNC:7920 +10830 NPM1P17 HGNC:HGNC:7919 +10831 NPM1P7 HGNC:HGNC:7927 +10833 NPM1P14 HGNC:HGNC:7916 +10834 NPM1P13 HGNC:HGNC:7915 +10835 NPM1P12 HGNC:HGNC:7914 +10836 NPM1P11 HGNC:HGNC:7913 +10837 NPM1P10 HGNC:HGNC:7912 +10838 ZNF275 HGNC:HGNC:13069|Ensembl:ENSG00000063587|Vega:OTTHUMG00000067450 +10840 ALDH1L1 MIM:600249|HGNC:HGNC:3978|Ensembl:ENSG00000144908|Vega:OTTHUMG00000125551 +10841 FTCD MIM:606806|HGNC:HGNC:3974|Ensembl:ENSG00000160282|Vega:OTTHUMG00000090488 +10842 PPP1R17 MIM:604088|HGNC:HGNC:16973|Ensembl:ENSG00000106341|Vega:OTTHUMG00000128629 +10844 TUBGCP2 HGNC:HGNC:18599|Ensembl:ENSG00000130640|Vega:OTTHUMG00000019319 +10845 CLPX MIM:615611|HGNC:HGNC:2088|Ensembl:ENSG00000166855|Vega:OTTHUMG00000133139 +10846 PDE10A MIM:610652|HGNC:HGNC:8772|Ensembl:ENSG00000112541|Vega:OTTHUMG00000015986 +10847 SRCAP MIM:611421|HGNC:HGNC:16974|Ensembl:ENSG00000080603|Ensembl:ENSG00000282034|Vega:OTTHUMG00000132393|Vega:OTTHUMG00000191413 +10848 PPP1R13L MIM:607463|HGNC:HGNC:18838|Ensembl:ENSG00000104881|Vega:OTTHUMG00000181784 +10849 CD3EAP MIM:107325|HGNC:HGNC:24219|Ensembl:ENSG00000117877|Vega:OTTHUMG00000182120 +10850 CCL27 MIM:604833|HGNC:HGNC:10626|Ensembl:ENSG00000213927|Vega:OTTHUMG00000019834 +10855 HPSE MIM:604724|HGNC:HGNC:5164|Ensembl:ENSG00000173083|Vega:OTTHUMG00000130425 +10856 RUVBL2 MIM:604788|HGNC:HGNC:10475|Ensembl:ENSG00000183207|Vega:OTTHUMG00000183333 +10857 PGRMC1 MIM:300435|HGNC:HGNC:16090|Ensembl:ENSG00000101856|Vega:OTTHUMG00000022268 +10858 CYP46A1 MIM:604087|HGNC:HGNC:2641|Ensembl:ENSG00000036530|Vega:OTTHUMG00000171510 +10859 LILRB1 MIM:604811|HGNC:HGNC:6605|Ensembl:ENSG00000104972|Vega:OTTHUMG00000065695 +10861 SLC26A1 MIM:610130|HGNC:HGNC:10993|Ensembl:ENSG00000145217|Vega:OTTHUMG00000160003 +10863 ADAM28 MIM:606188|HGNC:HGNC:206|Ensembl:ENSG00000042980|Vega:OTTHUMG00000163780 +10864 SLC22A7 MIM:604995|HGNC:HGNC:10971|Ensembl:ENSG00000137204|Vega:OTTHUMG00000014726 +10865 ARID5A MIM:611583|HGNC:HGNC:17361|Ensembl:ENSG00000196843|Vega:OTTHUMG00000155229 +10866 HCP5 MIM:604676|HGNC:HGNC:21659|Ensembl:ENSG00000206337 +10867 TSPAN9 MIM:613137|HGNC:HGNC:21640|Ensembl:ENSG00000011105|Vega:OTTHUMG00000150333 +10868 USP20 MIM:615143|HGNC:HGNC:12619|Ensembl:ENSG00000136878|Vega:OTTHUMG00000020793 +10869 USP19 MIM:614471|HGNC:HGNC:12617|Ensembl:ENSG00000172046|Vega:OTTHUMG00000133611 +10870 HCST MIM:604089|HGNC:HGNC:16977|Ensembl:ENSG00000126264|Vega:OTTHUMG00000048132 +10871 CD300C MIM:606786|HGNC:HGNC:19320|Ensembl:ENSG00000167850|Vega:OTTHUMG00000067608 +10873 ME3 MIM:604626|HGNC:HGNC:6985|Ensembl:ENSG00000151376|Vega:OTTHUMG00000167217 +10874 NMU MIM:605103|HGNC:HGNC:7859|Ensembl:ENSG00000109255|Vega:OTTHUMG00000102161 +10875 FGL2 MIM:605351|HGNC:HGNC:3696|Ensembl:ENSG00000127951|Vega:OTTHUMG00000130681 +10876 EDDM3A MIM:611580|HGNC:HGNC:16978|Ensembl:ENSG00000181562|Vega:OTTHUMG00000029581 +10877 CFHR4 MIM:605337|HGNC:HGNC:16979|Ensembl:ENSG00000134365|Vega:OTTHUMG00000036647 +10878 CFHR3 MIM:605336|HGNC:HGNC:16980|Ensembl:ENSG00000116785|Vega:OTTHUMG00000035929 +10879 SMR3B MIM:611593|HGNC:HGNC:17326|Ensembl:ENSG00000171201|Vega:OTTHUMG00000129396 +10880 ACTL7B MIM:604304|HGNC:HGNC:162|Ensembl:ENSG00000148156|Vega:OTTHUMG00000020462 +10881 ACTL7A MIM:604303|HGNC:HGNC:161|Ensembl:ENSG00000187003|Vega:OTTHUMG00000020461 +10882 C1QL1 MIM:611586|HGNC:HGNC:24182|Ensembl:ENSG00000131094|Vega:OTTHUMG00000162944 +10884 MRPS30 MIM:611991|HGNC:HGNC:8769|Ensembl:ENSG00000112996|Vega:OTTHUMG00000096967 +10885 WDR3 MIM:604737|HGNC:HGNC:12755|Ensembl:ENSG00000065183|Vega:OTTHUMG00000012197 +10886 NPFFR2 MIM:607449|HGNC:HGNC:4525|Ensembl:ENSG00000056291|Vega:OTTHUMG00000129918 +10887 PROKR1 MIM:607122|HGNC:HGNC:4524|Ensembl:ENSG00000169618|Ensembl:ENSG00000169621|Vega:OTTHUMG00000129567 +10888 GPR83 MIM:605569|HGNC:HGNC:4523|Ensembl:ENSG00000123901|Vega:OTTHUMG00000167779 +10890 RAB10 MIM:612672|HGNC:HGNC:9759|Ensembl:ENSG00000084733|Vega:OTTHUMG00000094796 +10891 PPARGC1A MIM:604517|HGNC:HGNC:9237|Ensembl:ENSG00000109819|Vega:OTTHUMG00000097747 +10892 MALT1 MIM:604860|HGNC:HGNC:6819|Ensembl:ENSG00000172175|Vega:OTTHUMG00000132761 +10893 MMP24 MIM:604871|HGNC:HGNC:7172|Ensembl:ENSG00000125966|Vega:OTTHUMG00000032330 +10894 LYVE1 MIM:605702|HGNC:HGNC:14687|Ensembl:ENSG00000133800|Vega:OTTHUMG00000165713 +10895 PPBPP2 MIM:611591|HGNC:HGNC:16981|Ensembl:ENSG00000248848 +10896 OCLM MIM:604301|HGNC:HGNC:8103|Ensembl:ENSG00000262180|Vega:OTTHUMG00000177601 +10897 YIF1A MIM:611484|HGNC:HGNC:16688|Ensembl:ENSG00000174851|Vega:OTTHUMG00000102079 +10898 CPSF4 MIM:603052|HGNC:HGNC:2327|Ensembl:ENSG00000160917|Vega:OTTHUMG00000154599 +10899 JTB MIM:604671|HGNC:HGNC:6201|Ensembl:ENSG00000143543|Vega:OTTHUMG00000036590 +10900 RUNDC3A MIM:605448|HGNC:HGNC:16984|Ensembl:ENSG00000108309|Vega:OTTHUMG00000169259 +10901 DHRS4 MIM:611596|HGNC:HGNC:16985|Ensembl:ENSG00000157326|Vega:OTTHUMG00000028777 +10902 BRD8 MIM:602848|HGNC:HGNC:19874|Ensembl:ENSG00000112983|Vega:OTTHUMG00000129204 +10903 MTMR11 HGNC:HGNC:24307|Ensembl:ENSG00000014914|Vega:OTTHUMG00000012207 +10904 BLCAP MIM:613110|HGNC:HGNC:1055|Ensembl:ENSG00000166619|Vega:OTTHUMG00000032419 +10905 MAN1A2 MIM:604345|HGNC:HGNC:6822|Ensembl:ENSG00000198162|Vega:OTTHUMG00000012149 +10906 TRAFD1 MIM:613197|HGNC:HGNC:24808|Ensembl:ENSG00000135148|Vega:OTTHUMG00000169640 +10907 TXNL4A MIM:611595|HGNC:HGNC:30551|Ensembl:ENSG00000141759|Vega:OTTHUMG00000180376 +10908 PNPLA6 MIM:603197|HGNC:HGNC:16268|Ensembl:ENSG00000032444|Vega:OTTHUMG00000182094 +10910 SUGT1 MIM:604098|HGNC:HGNC:16987|Ensembl:ENSG00000165416|Vega:OTTHUMG00000016977 +10911 UTS2 MIM:604097|HGNC:HGNC:12636|Ensembl:ENSG00000049247|Vega:OTTHUMG00000001218 +10912 GADD45G MIM:604949|HGNC:HGNC:4097|Ensembl:ENSG00000130222|Vega:OTTHUMG00000020187 +10913 EDAR MIM:604095|HGNC:HGNC:2895|Ensembl:ENSG00000135960|Vega:OTTHUMG00000130982 +10914 PAPOLA MIM:605553|HGNC:HGNC:14981|Ensembl:ENSG00000090060|Vega:OTTHUMG00000171441 +10915 TCERG1 MIM:605409|HGNC:HGNC:15630|Ensembl:ENSG00000113649|Vega:OTTHUMG00000129683 +10916 MAGED2 MIM:300470|HGNC:HGNC:16353|Ensembl:ENSG00000102316|Vega:OTTHUMG00000021638 +10917 BTNL3 MIM:606192|HGNC:HGNC:1143|Ensembl:ENSG00000168903|Vega:OTTHUMG00000162091 +10919 EHMT2 MIM:604599|HGNC:HGNC:14129|Ensembl:ENSG00000204371|Vega:OTTHUMG00000031180 +10920 COPS8 MIM:616011|HGNC:HGNC:24335|Ensembl:ENSG00000198612|Vega:OTTHUMG00000133297 +10921 RNPS1 MIM:606447|HGNC:HGNC:10080|Ensembl:ENSG00000205937|Vega:OTTHUMG00000128828 +10922 FASTK MIM:606965|HGNC:HGNC:24676|Ensembl:ENSG00000164896|Vega:OTTHUMG00000158694 +10923 SUB1 MIM:600503|HGNC:HGNC:19985|Ensembl:ENSG00000113387|Vega:OTTHUMG00000131071 +10924 SMPDL3A MIM:610728|HGNC:HGNC:17389|Ensembl:ENSG00000172594|Vega:OTTHUMG00000015490 +10926 DBF4 MIM:604281|HGNC:HGNC:17364|Ensembl:ENSG00000006634|Vega:OTTHUMG00000131034 +10927 SPIN1 MIM:609936|HGNC:HGNC:11243|Ensembl:ENSG00000106723|Vega:OTTHUMG00000020168 +10928 RALBP1 MIM:605801|HGNC:HGNC:9841|Ensembl:ENSG00000017797|Vega:OTTHUMG00000131596 +10929 SRSF8 MIM:603269|HGNC:HGNC:16988|Ensembl:ENSG00000263465|Vega:OTTHUMG00000188534 +10930 APOBEC2 MIM:604797|HGNC:HGNC:605|Ensembl:ENSG00000124701|Vega:OTTHUMG00000014670 +10933 MORF4L1 MIM:607303|HGNC:HGNC:16989|Ensembl:ENSG00000185787|Vega:OTTHUMG00000143865 +10934 MORF4 MIM:116960|HGNC:HGNC:15773 +10935 PRDX3 MIM:604769|HGNC:HGNC:9354|Ensembl:ENSG00000165672|Vega:OTTHUMG00000019146 +10936 GPR75 MIM:606704|HGNC:HGNC:4526|Ensembl:ENSG00000119737|Vega:OTTHUMG00000129280 +10938 EHD1 MIM:605888|HGNC:HGNC:3242|Ensembl:ENSG00000110047|Vega:OTTHUMG00000066832 +10939 AFG3L2 MIM:604581|HGNC:HGNC:315|Ensembl:ENSG00000141385|Vega:OTTHUMG00000131695 +10940 POP1 MIM:602486|HGNC:HGNC:30129|Ensembl:ENSG00000104356|Vega:OTTHUMG00000164635 +10941 UGT2A1 MIM:604716|HGNC:HGNC:12542|Ensembl:ENSG00000173610|Vega:OTTHUMG00000184942 +10942 PRSS21 MIM:608159|HGNC:HGNC:9485|Ensembl:ENSG00000007038|Vega:OTTHUMG00000128931 +10943 MSL3 MIM:300609|HGNC:HGNC:7370|Ensembl:ENSG00000005302|Vega:OTTHUMG00000021132 +10944 C11orf58 HGNC:HGNC:16990|Ensembl:ENSG00000110696|Vega:OTTHUMG00000165910 +10945 KDELR1 MIM:131235|HGNC:HGNC:6304|Ensembl:ENSG00000105438|Vega:OTTHUMG00000183215 +10946 SF3A3 MIM:605596|HGNC:HGNC:10767|Ensembl:ENSG00000183431|Vega:OTTHUMG00000004438 +10947 AP3M2 MIM:610469|HGNC:HGNC:570|Ensembl:ENSG00000070718|Vega:OTTHUMG00000164060 +10948 STARD3 MIM:607048|HGNC:HGNC:17579|Ensembl:ENSG00000131748|Vega:OTTHUMG00000133213 +10949 HNRNPA0 MIM:609409|HGNC:HGNC:5030|Ensembl:ENSG00000177733|Vega:OTTHUMG00000129156 +10950 BTG3 MIM:605674|HGNC:HGNC:1132|Ensembl:ENSG00000154640|Vega:OTTHUMG00000074501 +10951 CBX1 MIM:604511|HGNC:HGNC:1551|Ensembl:ENSG00000108468|Vega:OTTHUMG00000150417 +10952 SEC61B MIM:609214|HGNC:HGNC:16993|Ensembl:ENSG00000106803|Vega:OTTHUMG00000020354 +10953 TOMM34 MIM:616049|HGNC:HGNC:15746|Ensembl:ENSG00000025772|Vega:OTTHUMG00000032552 +10954 PDIA5 MIM:616942|HGNC:HGNC:24811|Ensembl:ENSG00000065485|Vega:OTTHUMG00000159558 +10955 SERINC3 MIM:607165|HGNC:HGNC:11699|Ensembl:ENSG00000132824|Vega:OTTHUMG00000033087 +10956 OS9 MIM:609677|HGNC:HGNC:16994|Ensembl:ENSG00000135506|Vega:OTTHUMG00000170284 +10957 PNRC1 MIM:606714|HGNC:HGNC:17278|Ensembl:ENSG00000146278|Vega:OTTHUMG00000015191 +10959 TMED2 HGNC:HGNC:16996|Ensembl:ENSG00000086598|Vega:OTTHUMG00000168694 +10960 LMAN2 MIM:609551|HGNC:HGNC:16986|Ensembl:ENSG00000169223|Vega:OTTHUMG00000130860 +10961 ERP29 MIM:602287|HGNC:HGNC:13799|Ensembl:ENSG00000089248|Vega:OTTHUMG00000169637 +10962 MLLT11 MIM:604684|HGNC:HGNC:16997|Ensembl:ENSG00000213190|Vega:OTTHUMG00000035160 +10963 STIP1 MIM:605063|HGNC:HGNC:11387|Ensembl:ENSG00000168439|Vega:OTTHUMG00000167789 +10964 IFI44L MIM:613975|HGNC:HGNC:17817|Ensembl:ENSG00000137959|Vega:OTTHUMG00000009724 +10965 ACOT2 MIM:609972|HGNC:HGNC:18431|Ensembl:ENSG00000119673|Vega:OTTHUMG00000171608 +10966 RAB40B HGNC:HGNC:18284|Ensembl:ENSG00000141542|Vega:OTTHUMG00000177806 +10969 EBNA1BP2 MIM:614443|HGNC:HGNC:15531|Ensembl:ENSG00000117395|Vega:OTTHUMG00000007284 +10970 CKAP4 HGNC:HGNC:16991|Ensembl:ENSG00000136026|Vega:OTTHUMG00000170085 +10971 YWHAQ MIM:609009|HGNC:HGNC:12854|Ensembl:ENSG00000134308|Vega:OTTHUMG00000013848 +10972 TMED10 MIM:605406|HGNC:HGNC:16998|Ensembl:ENSG00000170348|Vega:OTTHUMG00000171771 +10973 ASCC3 MIM:614217|HGNC:HGNC:18697|Ensembl:ENSG00000112249|Vega:OTTHUMG00000015279 +10974 ADIRF HGNC:HGNC:24043|Ensembl:ENSG00000148671|Vega:OTTHUMG00000018668 +10975 UQCR11 MIM:609711|HGNC:HGNC:30862|Ensembl:ENSG00000127540|Ensembl:ENSG00000267059|Vega:OTTHUMG00000180082|Vega:OTTHUMG00000180084 +10978 CLP1 MIM:608757|HGNC:HGNC:16999|Ensembl:ENSG00000172409|Vega:OTTHUMG00000167146 +10979 FERMT2 MIM:607746|HGNC:HGNC:15767|Ensembl:ENSG00000073712|Vega:OTTHUMG00000140309 +10980 COPS6 MIM:614729|HGNC:HGNC:21749|Ensembl:ENSG00000168090|Vega:OTTHUMG00000154632 +10981 RAB32 MIM:612906|HGNC:HGNC:9772|Ensembl:ENSG00000118508|Vega:OTTHUMG00000015755 +10982 MAPRE2 MIM:605789|HGNC:HGNC:6891|Ensembl:ENSG00000166974|Vega:OTTHUMG00000132551 +10983 CCNI HGNC:HGNC:1595|Ensembl:ENSG00000118816|Vega:OTTHUMG00000130106 +10984 KCNQ1OT1 MIM:604115|HGNC:HGNC:6295|Ensembl:ENSG00000269821 +10985 GCN1 MIM:605614|HGNC:HGNC:4199|Ensembl:ENSG00000089154|Vega:OTTHUMG00000169338 +10986 IGAD1 MIM:137100|HGNC:HGNC:5459 +10987 COPS5 MIM:604850|HGNC:HGNC:2240|Ensembl:ENSG00000121022|Vega:OTTHUMG00000164563 +10988 METAP2 MIM:601870|HGNC:HGNC:16672|Ensembl:ENSG00000111142|Vega:OTTHUMG00000170280 +10989 IMMT MIM:600378|HGNC:HGNC:6047|Ensembl:ENSG00000132305|Vega:OTTHUMG00000153170 +10990 LILRB5 MIM:604814|HGNC:HGNC:6609|Ensembl:ENSG00000105609|Vega:OTTHUMG00000066636 +10991 SLC38A3 MIM:604437|HGNC:HGNC:18044|Ensembl:ENSG00000188338|Vega:OTTHUMG00000156764 +10992 SF3B2 MIM:605591|HGNC:HGNC:10769|Ensembl:ENSG00000087365|Vega:OTTHUMG00000166751 +10993 SDS MIM:182128|HGNC:HGNC:10691|Ensembl:ENSG00000135094|Vega:OTTHUMG00000169554 +10994 ILVBL MIM:605770|HGNC:HGNC:6041|Ensembl:ENSG00000105135|Vega:OTTHUMG00000165630 +10998 SLC27A5 MIM:603314|HGNC:HGNC:10999|Ensembl:ENSG00000083807|Vega:OTTHUMG00000183543 +10999 SLC27A4 MIM:604194|HGNC:HGNC:10998|Ensembl:ENSG00000167114|Vega:OTTHUMG00000020746 +11000 SLC27A3 MIM:604193|HGNC:HGNC:10997|Ensembl:ENSG00000143554|Vega:OTTHUMG00000037155 +11001 SLC27A2 MIM:603247|HGNC:HGNC:10996|Ensembl:ENSG00000140284|Vega:OTTHUMG00000131643 +11004 KIF2C MIM:604538|HGNC:HGNC:6393|Ensembl:ENSG00000142945|Vega:OTTHUMG00000008416 +11005 SPINK5 MIM:605010|HGNC:HGNC:15464|Ensembl:ENSG00000133710|Vega:OTTHUMG00000134305 +11006 LILRB4 MIM:604821|HGNC:HGNC:6608|Ensembl:ENSG00000186818|Vega:OTTHUMG00000065879 +11007 CCDC85B MIM:605360|HGNC:HGNC:24926|Ensembl:ENSG00000175602|Vega:OTTHUMG00000166722 +11009 IL24 MIM:604136|HGNC:HGNC:11346|Ensembl:ENSG00000162892|Vega:OTTHUMG00000036459 +11010 GLIPR1 MIM:602692|HGNC:HGNC:17001|Ensembl:ENSG00000139278|Vega:OTTHUMG00000169757 +11011 TLK2 MIM:608439|HGNC:HGNC:11842|Ensembl:ENSG00000146872|Vega:OTTHUMG00000179176 +11012 KLK11 MIM:604434|HGNC:HGNC:6359|Ensembl:ENSG00000167757|Vega:OTTHUMG00000182915 +11013 TMSB15A MIM:300939|HGNC:HGNC:30744|Ensembl:ENSG00000158164|Vega:OTTHUMG00000022054 +11014 KDELR2 MIM:609024|HGNC:HGNC:6305|Ensembl:ENSG00000136240|Vega:OTTHUMG00000023103 +11015 KDELR3 HGNC:HGNC:6306|Ensembl:ENSG00000100196|Vega:OTTHUMG00000153520 +11016 ATF7 MIM:606371|HGNC:HGNC:792|Ensembl:ENSG00000170653|Vega:OTTHUMG00000169776 +11017 SNRNP27 HGNC:HGNC:30240|Ensembl:ENSG00000124380|Vega:OTTHUMG00000152689 +11018 TMED1 MIM:605395|HGNC:HGNC:17291|Ensembl:ENSG00000099203|Vega:OTTHUMG00000180696 +11019 LIAS MIM:607031|HGNC:HGNC:16429|Ensembl:ENSG00000121897|Vega:OTTHUMG00000099369 +11020 IFT27 MIM:615870|HGNC:HGNC:18626|Ensembl:ENSG00000100360|Vega:OTTHUMG00000150544 +11021 RAB35 MIM:604199|HGNC:HGNC:9774|Ensembl:ENSG00000111737|Vega:OTTHUMG00000169159 +11022 TDRKH MIM:609501|HGNC:HGNC:11713|Ensembl:ENSG00000182134|Vega:OTTHUMG00000013062 +11023 VAX1 MIM:604294|HGNC:HGNC:12660|Ensembl:ENSG00000148704|Vega:OTTHUMG00000019117 +11024 LILRA1 MIM:604810|HGNC:HGNC:6602|Ensembl:ENSG00000104974|Vega:OTTHUMG00000065701 +11025 LILRB3 MIM:604820|HGNC:HGNC:6607|Ensembl:ENSG00000204577|Vega:OTTHUMG00000066626 +11026 LILRA3 MIM:604818|HGNC:HGNC:6604 +11027 LILRA2 MIM:604812|HGNC:HGNC:6603|Ensembl:ENSG00000239998|Vega:OTTHUMG00000065703 +11029 SERPINB8P1 HGNC:HGNC:8953 +11030 RBPMS MIM:601558|HGNC:HGNC:19097|Ensembl:ENSG00000157110|Vega:OTTHUMG00000163845 +11031 RAB31 MIM:605694|HGNC:HGNC:9771|Ensembl:ENSG00000168461|Vega:OTTHUMG00000178513 +11033 ADAP1 MIM:608114|HGNC:HGNC:16486|Ensembl:ENSG00000105963|Vega:OTTHUMG00000023380 +11034 DSTN MIM:609114|HGNC:HGNC:15750|Ensembl:ENSG00000125868|Vega:OTTHUMG00000031947 +11035 RIPK3 MIM:605817|HGNC:HGNC:10021|Ensembl:ENSG00000129465|Vega:OTTHUMG00000029349 +11036 GTF2A1L MIM:605358|HGNC:HGNC:30727|Ensembl:ENSG00000242441|Vega:OTTHUMG00000152038 +11037 STON1 MIM:605357|HGNC:HGNC:17003|Ensembl:ENSG00000243244|Vega:OTTHUMG00000129169 +11039 SMA4 - +11040 PIM2 MIM:300295|HGNC:HGNC:8987|Ensembl:ENSG00000102096|Vega:OTTHUMG00000024132 +11041 B4GAT1 MIM:605517|HGNC:HGNC:15685|Ensembl:ENSG00000174684|Vega:OTTHUMG00000167082 +11042 SMA5 - +11043 MID2 MIM:300204|HGNC:HGNC:7096|Ensembl:ENSG00000080561|Vega:OTTHUMG00000022171 +11044 PAPD7 MIM:605198|HGNC:HGNC:16705|Ensembl:ENSG00000112941|Vega:OTTHUMG00000090457 +11045 UPK1A MIM:611557|HGNC:HGNC:12577|Ensembl:ENSG00000105668|Vega:OTTHUMG00000048115 +11046 SLC35D2 MIM:609182|HGNC:HGNC:20799|Ensembl:ENSG00000130958|Vega:OTTHUMG00000020293 +11047 ADRM1 MIM:610650|HGNC:HGNC:15759|Ensembl:ENSG00000130706|Vega:OTTHUMG00000032904 +11049 NUS1P3 HGNC:HGNC:30934 +11051 NUDT21 MIM:604978|HGNC:HGNC:13870|Ensembl:ENSG00000167005|Vega:OTTHUMG00000133240 +11052 CPSF6 MIM:604979|HGNC:HGNC:13871|Ensembl:ENSG00000111605|Vega:OTTHUMG00000169340 +11054 OGFR MIM:606459|HGNC:HGNC:15768|Ensembl:ENSG00000060491|Vega:OTTHUMG00000032937 +11055 ZPBP MIM:608498|HGNC:HGNC:15662|Ensembl:ENSG00000042813|Vega:OTTHUMG00000023528 +11056 DDX52 MIM:612500|HGNC:HGNC:20038|Ensembl:ENSG00000278053|Vega:OTTHUMG00000188475 +11057 ABHD2 MIM:612196|HGNC:HGNC:18717|Ensembl:ENSG00000140526|Vega:OTTHUMG00000148684 +11059 WWP1 MIM:602307|HGNC:HGNC:17004|Ensembl:ENSG00000123124|Vega:OTTHUMG00000163690 +11060 WWP2 MIM:602308|HGNC:HGNC:16804|Ensembl:ENSG00000198373|Vega:OTTHUMG00000137573 +11061 CNMD MIM:605147|HGNC:HGNC:17005|Ensembl:ENSG00000136110|Vega:OTTHUMG00000016980 +11062 DUS4L HGNC:HGNC:21517|Ensembl:ENSG00000105865|Vega:OTTHUMG00000154763 +11063 SOX30 MIM:606698|HGNC:HGNC:30635|Ensembl:ENSG00000039600|Vega:OTTHUMG00000130247 +11064 CNTRL MIM:605496|HGNC:HGNC:1858|Ensembl:ENSG00000119397|Vega:OTTHUMG00000020581 +11065 UBE2C MIM:605574|HGNC:HGNC:15937|Ensembl:ENSG00000175063|Vega:OTTHUMG00000033038 +11066 SNRNP35 HGNC:HGNC:30852|Ensembl:ENSG00000184209|Vega:OTTHUMG00000167584 +11067 C10orf10 MIM:611309|HGNC:HGNC:23355|Ensembl:ENSG00000165507|Vega:OTTHUMG00000018063 +11068 CYB561D2 MIM:607068|HGNC:HGNC:30253|Ensembl:ENSG00000114395|Ensembl:ENSG00000271858|Vega:OTTHUMG00000156813 +11069 RAPGEF4 MIM:606058|HGNC:HGNC:16626|Ensembl:ENSG00000091428|Vega:OTTHUMG00000133677 +11070 TMEM115 MIM:607069|HGNC:HGNC:30055|Ensembl:ENSG00000126062|Vega:OTTHUMG00000044212 +11072 DUSP14 MIM:606618|HGNC:HGNC:17007|Ensembl:ENSG00000276023|Vega:OTTHUMG00000188472 +11073 TOPBP1 MIM:607760|HGNC:HGNC:17008|Ensembl:ENSG00000163781|Vega:OTTHUMG00000159773 +11074 TRIM31 MIM:609316|HGNC:HGNC:16289|Ensembl:ENSG00000204616|Vega:OTTHUMG00000031064 +11075 STMN2 MIM:600621|HGNC:HGNC:10577|Ensembl:ENSG00000104435|Vega:OTTHUMG00000164610 +11076 TPPP MIM:608773|HGNC:HGNC:24164|Ensembl:ENSG00000171368|Vega:OTTHUMG00000131011 +11077 HSF2BP MIM:604554|HGNC:HGNC:5226|Ensembl:ENSG00000160207|Vega:OTTHUMG00000086863 +11078 TRIOBP MIM:609761|HGNC:HGNC:17009|Ensembl:ENSG00000100106|Vega:OTTHUMG00000150657 +11079 RER1 HGNC:HGNC:30309|Ensembl:ENSG00000157916|Vega:OTTHUMG00000001403 +11080 DNAJB4 MIM:611327|HGNC:HGNC:14886|Ensembl:ENSG00000162616|Vega:OTTHUMG00000040905 +11081 KERA MIM:603288|HGNC:HGNC:6309|Ensembl:ENSG00000139330|Vega:OTTHUMG00000170073 +11082 ESM1 MIM:601521|HGNC:HGNC:3466|Ensembl:ENSG00000164283|Vega:OTTHUMG00000097010 +11083 DIDO1 MIM:604140|HGNC:HGNC:2680|Ensembl:ENSG00000101191|Vega:OTTHUMG00000032945 +11085 ADAM30 MIM:604779|HGNC:HGNC:208|Ensembl:ENSG00000134249|Vega:OTTHUMG00000189303 +11086 ADAM29 MIM:604778|HGNC:HGNC:207|Ensembl:ENSG00000168594|Vega:OTTHUMG00000160764 +11091 WDR5 MIM:609012|HGNC:HGNC:12757|Ensembl:ENSG00000196363|Vega:OTTHUMG00000131707 +11092 SPACA9 HGNC:HGNC:1367|Ensembl:ENSG00000165698|Vega:OTTHUMG00000020847 +11093 ADAMTS13 MIM:604134|HGNC:HGNC:1366|Ensembl:ENSG00000160323|Vega:OTTHUMG00000020876 +11094 CACFD1 MIM:613104|HGNC:HGNC:1365|Ensembl:ENSG00000160325|Vega:OTTHUMG00000020875 +11095 ADAMTS8 MIM:605175|HGNC:HGNC:224|Ensembl:ENSG00000134917|Vega:OTTHUMG00000165656 +11096 ADAMTS5 MIM:605007|HGNC:HGNC:221|Ensembl:ENSG00000154736|Vega:OTTHUMG00000078686 +11097 NUPL2 HGNC:HGNC:17010|Ensembl:ENSG00000136243|Vega:OTTHUMG00000096955 +11098 PRSS23 HGNC:HGNC:14370|Ensembl:ENSG00000150687|Vega:OTTHUMG00000167226 +11099 PTPN21 MIM:603271|HGNC:HGNC:9651|Ensembl:ENSG00000070778|Vega:OTTHUMG00000170766 +11100 HNRNPUL1 MIM:605800|HGNC:HGNC:17011|Ensembl:ENSG00000105323|Vega:OTTHUMG00000182740 +11101 ATE1 MIM:607103|HGNC:HGNC:782|Ensembl:ENSG00000107669|Vega:OTTHUMG00000019178 +11102 RPP14 MIM:606112|HGNC:HGNC:30327|Ensembl:ENSG00000163684|Vega:OTTHUMG00000159152 +11103 KRR1 MIM:612817|HGNC:HGNC:5176|Ensembl:ENSG00000111615|Vega:OTTHUMG00000169759 +11104 KATNA1 MIM:606696|HGNC:HGNC:6216|Ensembl:ENSG00000186625|Vega:OTTHUMG00000015787 +11105 PRDM7 MIM:609759|HGNC:HGNC:9351|Ensembl:ENSG00000126856|Vega:OTTHUMG00000138990 +11107 PRDM5 MIM:614161|HGNC:HGNC:9349|Ensembl:ENSG00000138738|Vega:OTTHUMG00000132970 +11108 PRDM4 MIM:605780|HGNC:HGNC:9348|Ensembl:ENSG00000110851|Vega:OTTHUMG00000169914 +11112 HIBADH MIM:608475|HGNC:HGNC:4907|Ensembl:ENSG00000106049|Vega:OTTHUMG00000097035 +11113 CIT MIM:605629|HGNC:HGNC:1985|Ensembl:ENSG00000122966|Vega:OTTHUMG00000134325 +11116 FGFR1OP MIM:605392|HGNC:HGNC:17012|Ensembl:ENSG00000213066|Vega:OTTHUMG00000016011 +11117 EMILIN1 MIM:130660|HGNC:HGNC:19880|Ensembl:ENSG00000138080|Vega:OTTHUMG00000097069 +11118 BTN3A2 MIM:613594|HGNC:HGNC:1139|Ensembl:ENSG00000186470|Vega:OTTHUMG00000014450 +11119 BTN3A1 MIM:613593|HGNC:HGNC:1138|Ensembl:ENSG00000026950|Vega:OTTHUMG00000014449 +11120 BTN2A1 MIM:613590|HGNC:HGNC:1136|Ensembl:ENSG00000112763|Vega:OTTHUMG00000014457 +11122 PTPRT MIM:608712|HGNC:HGNC:9682|Ensembl:ENSG00000196090|Vega:OTTHUMG00000033040 +11123 RCAN3 MIM:605860|HGNC:HGNC:3042|Ensembl:ENSG00000117602|Vega:OTTHUMG00000003298 +11124 FAF1 MIM:604460|HGNC:HGNC:3578|Ensembl:ENSG00000185104|Vega:OTTHUMG00000007930 +11126 CD160 MIM:604463|HGNC:HGNC:17013|Ensembl:ENSG00000117281|Vega:OTTHUMG00000013749 +11127 KIF3A MIM:604683|HGNC:HGNC:6319|Ensembl:ENSG00000131437|Vega:OTTHUMG00000059725 +11128 POLR3A MIM:614258|HGNC:HGNC:30074|Ensembl:ENSG00000148606|Vega:OTTHUMG00000018550 +11129 CLASRP HGNC:HGNC:17731|Ensembl:ENSG00000104859|Vega:OTTHUMG00000150189 +11130 ZWINT MIM:609177|HGNC:HGNC:13195|Ensembl:ENSG00000122952|Vega:OTTHUMG00000018261 +11131 CAPN11 MIM:604822|HGNC:HGNC:1478|Ensembl:ENSG00000137225|Vega:OTTHUMG00000014758 +11132 CAPN10 MIM:605286|HGNC:HGNC:1477|Ensembl:ENSG00000142330|Vega:OTTHUMG00000133358 +11133 KPTN MIM:615620|HGNC:HGNC:6404|Ensembl:ENSG00000118162|Vega:OTTHUMG00000183443 +11135 CDC42EP1 MIM:606084|HGNC:HGNC:17014|Ensembl:ENSG00000128283|Vega:OTTHUMG00000150591 +11136 SLC7A9 MIM:604144|HGNC:HGNC:11067|Ensembl:ENSG00000021488|Vega:OTTHUMG00000180287 +11137 PWP1 HGNC:HGNC:17015|Ensembl:ENSG00000136045|Vega:OTTHUMG00000169913 +11138 TBC1D8 HGNC:HGNC:17791|Ensembl:ENSG00000204634|Vega:OTTHUMG00000153040 +11140 CDC37 MIM:605065|HGNC:HGNC:1735|Ensembl:ENSG00000105401|Vega:OTTHUMG00000180578 +11141 IL1RAPL1 MIM:300206|HGNC:HGNC:5996|Ensembl:ENSG00000169306|Vega:OTTHUMG00000021317 +11142 PKIG MIM:604932|HGNC:HGNC:9019|Ensembl:ENSG00000168734|Vega:OTTHUMG00000033065 +11143 KAT7 MIM:609880|HGNC:HGNC:17016|Ensembl:ENSG00000136504|Vega:OTTHUMG00000161770 +11144 DMC1 MIM:602721|HGNC:HGNC:2927|Ensembl:ENSG00000100206|Vega:OTTHUMG00000151088 +11145 PLA2G16 MIM:613867|HGNC:HGNC:17825|Ensembl:ENSG00000176485|Vega:OTTHUMG00000167852 +11146 GLMN MIM:601749|HGNC:HGNC:14373|Ensembl:ENSG00000174842|Vega:OTTHUMG00000010283 +11147 HHLA3 MIM:604372|HGNC:HGNC:4906|Ensembl:ENSG00000197568|Vega:OTTHUMG00000009346 +11148 HHLA2 MIM:604371|HGNC:HGNC:4905|Ensembl:ENSG00000114455|Vega:OTTHUMG00000159224 +11149 BVES MIM:604577|HGNC:HGNC:1152|Ensembl:ENSG00000112276|Vega:OTTHUMG00000015291 +11151 CORO1A MIM:605000|HGNC:HGNC:2252|Ensembl:ENSG00000102879|Vega:OTTHUMG00000132148 +11152 WDR45 MIM:300526|HGNC:HGNC:28912|Ensembl:ENSG00000196998|Vega:OTTHUMG00000034500 +11153 FICD HGNC:HGNC:18416|Ensembl:ENSG00000198855|Vega:OTTHUMG00000169569 +11154 AP4S1 MIM:607243|HGNC:HGNC:575|Ensembl:ENSG00000100478|Vega:OTTHUMG00000140202 +11155 LDB3 MIM:605906|HGNC:HGNC:15710|Ensembl:ENSG00000122367|Vega:OTTHUMG00000018655 +11156 PTP4A3 MIM:606449|HGNC:HGNC:9636|Ensembl:ENSG00000184489|Vega:OTTHUMG00000164490 +11157 LSM6 MIM:607286|HGNC:HGNC:17017|Ensembl:ENSG00000164167|Vega:OTTHUMG00000161440 +11158 RABL2B MIM:605413|HGNC:HGNC:9800|Ensembl:ENSG00000079974|Vega:OTTHUMG00000150156 +11159 RABL2A MIM:605412|HGNC:HGNC:9799|Ensembl:ENSG00000144134|Vega:OTTHUMG00000047828 +11160 ERLIN2 MIM:611605|HGNC:HGNC:1356|Ensembl:ENSG00000147475|Vega:OTTHUMG00000164005 +11161 ERG28 MIM:604576|HGNC:HGNC:1187|Ensembl:ENSG00000133935|Vega:OTTHUMG00000171488 +11162 NUDT6 MIM:606261|HGNC:HGNC:8053|Ensembl:ENSG00000170917|Vega:OTTHUMG00000039507 +11163 NUDT4 MIM:609229|HGNC:HGNC:8051|Ensembl:ENSG00000173598|Vega:OTTHUMG00000170155 +11164 NUDT5 MIM:609230|HGNC:HGNC:8052|Ensembl:ENSG00000165609|Vega:OTTHUMG00000017682 +11165 NUDT3 MIM:609228|HGNC:HGNC:8050|Ensembl:ENSG00000272325|Vega:OTTHUMG00000014545 +11166 SOX21 MIM:604974|HGNC:HGNC:11197|Ensembl:ENSG00000125285|Vega:OTTHUMG00000017209 +11167 FSTL1 MIM:605547|HGNC:HGNC:3972|Ensembl:ENSG00000163430|Vega:OTTHUMG00000159440 +11168 PSIP1 MIM:603620|HGNC:HGNC:9527|Ensembl:ENSG00000164985|Vega:OTTHUMG00000021021 +11169 WDHD1 MIM:608126|HGNC:HGNC:23170|Ensembl:ENSG00000198554|Vega:OTTHUMG00000140304 +11170 FAM107A MIM:608295|HGNC:HGNC:30827|Ensembl:ENSG00000168309|Vega:OTTHUMG00000159159 +11171 STRAP MIM:605986|HGNC:HGNC:30796|Ensembl:ENSG00000023734|Vega:OTTHUMG00000168791 +11172 INSL6 MIM:606414|HGNC:HGNC:6089|Ensembl:ENSG00000120210|Vega:OTTHUMG00000019489 +11173 ADAMTS7 MIM:605009|HGNC:HGNC:223|Ensembl:ENSG00000136378|Vega:OTTHUMG00000172907 +11174 ADAMTS6 MIM:605008|HGNC:HGNC:222|Ensembl:ENSG00000049192|Vega:OTTHUMG00000074079 +11176 BAZ2A MIM:605682|HGNC:HGNC:962|Ensembl:ENSG00000076108|Vega:OTTHUMG00000170332 +11177 BAZ1A MIM:605680|HGNC:HGNC:960|Ensembl:ENSG00000198604|Vega:OTTHUMG00000140216 +11178 LZTS1 MIM:606551|HGNC:HGNC:13861|Ensembl:ENSG00000061337|Vega:OTTHUMG00000097027 +11179 ZNF277 MIM:605465|HGNC:HGNC:13070|Ensembl:ENSG00000198839|Vega:OTTHUMG00000150209 +11180 WDR6 MIM:606031|HGNC:HGNC:12758|Ensembl:ENSG00000178252|Vega:OTTHUMG00000133546 +11181 TREH MIM:275360|HGNC:HGNC:12266|Ensembl:ENSG00000118094|Vega:OTTHUMG00000166409 +11182 SLC2A6 MIM:606813|HGNC:HGNC:11011|Ensembl:ENSG00000160326|Vega:OTTHUMG00000020874 +11183 MAP4K5 MIM:604923|HGNC:HGNC:6867|Ensembl:ENSG00000012983|Vega:OTTHUMG00000170888 +11184 MAP4K1 MIM:601983|HGNC:HGNC:6863|Ensembl:ENSG00000104814|Vega:OTTHUMG00000180863 +11185 INMT MIM:604854|HGNC:HGNC:6069|Ensembl:ENSG00000241644|Vega:OTTHUMG00000167163 +11186 RASSF1 MIM:605082|HGNC:HGNC:9882|Ensembl:ENSG00000068028|Vega:OTTHUMG00000149958 +11187 PKP3 MIM:605561|HGNC:HGNC:9025|Ensembl:ENSG00000184363|Vega:OTTHUMG00000119068 +11188 NISCH MIM:615507|HGNC:HGNC:18006|Ensembl:ENSG00000010322|Vega:OTTHUMG00000158571 +11189 CELF3 MIM:612678|HGNC:HGNC:11967|Ensembl:ENSG00000159409|Vega:OTTHUMG00000013064 +11190 CEP250 MIM:609689|HGNC:HGNC:1859|Ensembl:ENSG00000126001|Vega:OTTHUMG00000032343 +11191 PTENP1 MIM:613531|HGNC:HGNC:9589|Ensembl:ENSG00000237984 +11192 DYX3 MIM:604254|HGNC:HGNC:3110 +11193 WBP4 MIM:604981|HGNC:HGNC:12739|Ensembl:ENSG00000120688|Vega:OTTHUMG00000016784 +11194 ABCB8 MIM:605464|HGNC:HGNC:49|Ensembl:ENSG00000197150|Vega:OTTHUMG00000158686 +11196 SEC23IP HGNC:HGNC:17018|Ensembl:ENSG00000107651|Vega:OTTHUMG00000019161 +11197 WIF1 MIM:605186|HGNC:HGNC:18081|Ensembl:ENSG00000156076|Vega:OTTHUMG00000168832 +11198 SUPT16H MIM:605012|HGNC:HGNC:11465|Ensembl:ENSG00000092201|Vega:OTTHUMG00000029685 +11199 ANXA10 MIM:608008|HGNC:HGNC:534|Ensembl:ENSG00000109511|Vega:OTTHUMG00000161275 +11200 CHEK2 MIM:604373|HGNC:HGNC:16627|Ensembl:ENSG00000183765|Vega:OTTHUMG00000151023 +11201 POLI MIM:605252|HGNC:HGNC:9182|Ensembl:ENSG00000101751|Vega:OTTHUMG00000132704 +11202 KLK8 MIM:605644|HGNC:HGNC:6369|Ensembl:ENSG00000129455|Vega:OTTHUMG00000183086 +11209 MST1P2 HGNC:HGNC:7383 +11211 FZD10 MIM:606147|HGNC:HGNC:4039|Ensembl:ENSG00000111432 +11212 PLPBP MIM:604436|HGNC:HGNC:9457|Ensembl:ENSG00000147471|Vega:OTTHUMG00000164024 +11213 IRAK3 MIM:604459|HGNC:HGNC:17020|Ensembl:ENSG00000090376|Vega:OTTHUMG00000169002 +11214 AKAP13 MIM:604686|HGNC:HGNC:371|Ensembl:ENSG00000170776|Vega:OTTHUMG00000172205 +11215 AKAP11 MIM:604696|HGNC:HGNC:369|Ensembl:ENSG00000023516|Vega:OTTHUMG00000016805 +11216 AKAP10 MIM:604694|HGNC:HGNC:368|Ensembl:ENSG00000108599|Vega:OTTHUMG00000059515 +11217 AKAP2 MIM:604582|HGNC:HGNC:372|Ensembl:ENSG00000241978|Vega:OTTHUMG00000156811 +11218 DDX20 MIM:606168|HGNC:HGNC:2743|Ensembl:ENSG00000064703|Vega:OTTHUMG00000011956 +11219 TREX2 MIM:300370|HGNC:HGNC:12270|Ensembl:ENSG00000183479|Vega:OTTHUMG00000159319 +11221 DUSP10 MIM:608867|HGNC:HGNC:3065|Ensembl:ENSG00000143507|Vega:OTTHUMG00000037269 +11222 MRPL3 MIM:607118|HGNC:HGNC:10379|Ensembl:ENSG00000114686|Vega:OTTHUMG00000159607 +11223 MST1L HGNC:HGNC:7390 +11224 RPL35 HGNC:HGNC:10344|Ensembl:ENSG00000136942|Vega:OTTHUMG00000020659 +11226 GALNT6 MIM:605148|HGNC:HGNC:4128|Ensembl:ENSG00000139629|Vega:OTTHUMG00000185181 +11227 GALNT5 MIM:615129|HGNC:HGNC:4127|Ensembl:ENSG00000136542|Vega:OTTHUMG00000131965 +11228 RASSF8 MIM:608231|HGNC:HGNC:13232|Ensembl:ENSG00000123094|Vega:OTTHUMG00000169087 +11230 PRAF2 MIM:300840|HGNC:HGNC:28911|Ensembl:ENSG00000243279|Vega:OTTHUMG00000034499 +11231 SEC63 MIM:608648|HGNC:HGNC:21082|Ensembl:ENSG00000025796|Vega:OTTHUMG00000015316 +11232 POLG2 MIM:604983|HGNC:HGNC:9180|Ensembl:ENSG00000256525|Vega:OTTHUMG00000178899 +11234 HPS5 MIM:607521|HGNC:HGNC:17022|Ensembl:ENSG00000110756|Vega:OTTHUMG00000166612 +11235 PDCD10 MIM:609118|HGNC:HGNC:8761|Ensembl:ENSG00000114209|Vega:OTTHUMG00000158415 +11236 RNF139 MIM:603046|HGNC:HGNC:17023|Ensembl:ENSG00000170881|Vega:OTTHUMG00000165072 +11237 RNF24 MIM:612489|HGNC:HGNC:13779|Ensembl:ENSG00000101236|Vega:OTTHUMG00000031770 +11238 CA5B MIM:300230|HGNC:HGNC:1378|Ensembl:ENSG00000169239|Vega:OTTHUMG00000021183 +11240 PADI2 MIM:607935|HGNC:HGNC:18341|Ensembl:ENSG00000117115|Vega:OTTHUMG00000002295 +11243 PMF1 MIM:609176|HGNC:HGNC:9112|Ensembl:ENSG00000160783|Vega:OTTHUMG00000177123 +11244 ZHX1 MIM:604764|HGNC:HGNC:12871|Ensembl:ENSG00000165156|Vega:OTTHUMG00000165088 +11245 GPR176 MIM:612183|HGNC:HGNC:32370|Ensembl:ENSG00000166073|Vega:OTTHUMG00000129873 +11247 NXPH4 MIM:604637|HGNC:HGNC:8078|Ensembl:ENSG00000182379|Vega:OTTHUMG00000171241 +11248 NXPH3 MIM:604636|HGNC:HGNC:8077|Ensembl:ENSG00000182575|Vega:OTTHUMG00000161491 +11249 NXPH2 MIM:604635|HGNC:HGNC:8076|Ensembl:ENSG00000144227|Vega:OTTHUMG00000153636 +11250 GPR45 MIM:604838|HGNC:HGNC:4503|Ensembl:ENSG00000135973|Vega:OTTHUMG00000130805 +11251 PTGDR2 MIM:604837|HGNC:HGNC:4502|Ensembl:ENSG00000183134|Vega:OTTHUMG00000167796 +11252 PACSIN2 MIM:604960|HGNC:HGNC:8571|Ensembl:ENSG00000100266|Vega:OTTHUMG00000150701 +11253 MAN1B1 MIM:604346|HGNC:HGNC:6823|Ensembl:ENSG00000177239|Vega:OTTHUMG00000020978 +11254 SLC6A14 MIM:300444|HGNC:HGNC:11047|Ensembl:ENSG00000268104|Vega:OTTHUMG00000022245 +11255 HRH3 MIM:604525|HGNC:HGNC:5184|Ensembl:ENSG00000101180|Vega:OTTHUMG00000032899 +11257 TP53TG1 MIM:616403|HGNC:HGNC:17026|Ensembl:ENSG00000182165 +11258 DCTN3 MIM:607387|HGNC:HGNC:2713|Ensembl:ENSG00000137100|Vega:OTTHUMG00000019830 +11259 FILIP1L MIM:612993|HGNC:HGNC:24589|Ensembl:ENSG00000168386|Vega:OTTHUMG00000159055 +11260 XPOT MIM:603180|HGNC:HGNC:12826|Ensembl:ENSG00000184575|Vega:OTTHUMG00000168794 +11261 CHP1 MIM:606988|HGNC:HGNC:17433|Ensembl:ENSG00000187446|Vega:OTTHUMG00000130233 +11262 SP140 MIM:608602|HGNC:HGNC:17133|Ensembl:ENSG00000079263|Vega:OTTHUMG00000153670 +11264 PXMP4 MIM:616397|HGNC:HGNC:15920|Ensembl:ENSG00000101417|Vega:OTTHUMG00000032273 +11266 DUSP12 MIM:604835|HGNC:HGNC:3067|Ensembl:ENSG00000081721|Vega:OTTHUMG00000034540 +11267 SNF8 MIM:610904|HGNC:HGNC:17028|Ensembl:ENSG00000159210|Vega:OTTHUMG00000160569 +11269 DDX19B MIM:605812|HGNC:HGNC:2742|Ensembl:ENSG00000157349|Vega:OTTHUMG00000137577 +11270 NRM HGNC:HGNC:8003|Ensembl:ENSG00000137404|Vega:OTTHUMG00000031223 +11272 PRR4 MIM:605359|HGNC:HGNC:18020|Ensembl:ENSG00000111215|Vega:OTTHUMG00000168522 +11273 ATXN2L MIM:607931|HGNC:HGNC:31326|Ensembl:ENSG00000168488|Vega:OTTHUMG00000097038 +11274 USP18 MIM:607057|HGNC:HGNC:12616|Ensembl:ENSG00000184979|Vega:OTTHUMG00000150104 +11275 KLHL2 MIM:605774|HGNC:HGNC:6353|Ensembl:ENSG00000109466|Vega:OTTHUMG00000161294 +11276 SYNRG MIM:607291|HGNC:HGNC:557|Ensembl:ENSG00000275066|Vega:OTTHUMG00000188473 +11277 TREX1 MIM:606609|HGNC:HGNC:12269|Ensembl:ENSG00000213689|Vega:OTTHUMG00000156205|Vega:OTTHUMG00000190127 +11278 KLF12 MIM:607531|HGNC:HGNC:6346|Ensembl:ENSG00000118922|Vega:OTTHUMG00000017078 +11279 KLF8 MIM:300286|HGNC:HGNC:6351|Ensembl:ENSG00000102349|Vega:OTTHUMG00000021666 +11280 SCN11A MIM:604385|HGNC:HGNC:10583|Ensembl:ENSG00000168356|Vega:OTTHUMG00000048246 +11281 POU6F2 MIM:609062|HGNC:HGNC:21694|Ensembl:ENSG00000106536|Vega:OTTHUMG00000150803 +11282 MGAT4B MIM:604561|HGNC:HGNC:7048|Ensembl:ENSG00000161013|Vega:OTTHUMG00000130912 +11283 CYP4F8 MIM:611545|HGNC:HGNC:2648|Ensembl:ENSG00000186526|Vega:OTTHUMG00000182386 +11284 PNKP MIM:605610|HGNC:HGNC:9154|Ensembl:ENSG00000039650|Vega:OTTHUMG00000183261 +11285 B4GALT7 MIM:604327|HGNC:HGNC:930|Ensembl:ENSG00000027847|Vega:OTTHUMG00000130851 +11309 SLCO2B1 MIM:604988|HGNC:HGNC:10962|Ensembl:ENSG00000137491|Vega:OTTHUMG00000165420 +11311 VPS45 MIM:610035|HGNC:HGNC:14579|Ensembl:ENSG00000136631|Vega:OTTHUMG00000012511 +11313 LYPLA2 MIM:616143|HGNC:HGNC:6738|Ensembl:ENSG00000011009|Vega:OTTHUMG00000002961 +11314 CD300A MIM:606790|HGNC:HGNC:19319|Ensembl:ENSG00000167851|Vega:OTTHUMG00000067612 +11315 PARK7 MIM:602533|HGNC:HGNC:16369|Ensembl:ENSG00000116288|Vega:OTTHUMG00000001210 +11316 COPE MIM:606942|HGNC:HGNC:2234|Ensembl:ENSG00000105669|Vega:OTTHUMG00000183052 +11317 RBPJL MIM:616104|HGNC:HGNC:13761|Ensembl:ENSG00000124232|Vega:OTTHUMG00000033055 +11318 GPR182 MIM:605307|HGNC:HGNC:13708|Ensembl:ENSG00000166856|Vega:OTTHUMG00000171005 +11319 ECD MIM:616464|HGNC:HGNC:17029|Ensembl:ENSG00000122882|Vega:OTTHUMG00000018451 +11320 MGAT4A MIM:604623|HGNC:HGNC:7047|Ensembl:ENSG00000071073|Vega:OTTHUMG00000130563 +11321 GPN1 MIM:611479|HGNC:HGNC:17030|Ensembl:ENSG00000198522|Vega:OTTHUMG00000097784 +11322 TMC6 MIM:605828|HGNC:HGNC:18021|Ensembl:ENSG00000141524|Vega:OTTHUMG00000177466 +11325 DDX42 MIM:613369|HGNC:HGNC:18676|Ensembl:ENSG00000198231|Vega:OTTHUMG00000179011 +11326 VSIG4 MIM:300353|HGNC:HGNC:17032|Ensembl:ENSG00000155659|Vega:OTTHUMG00000021727 +11328 FKBP9 MIM:616257|HGNC:HGNC:3725|Ensembl:ENSG00000122642|Vega:OTTHUMG00000097847 +11329 STK38 MIM:606964|HGNC:HGNC:17847|Ensembl:ENSG00000112079|Vega:OTTHUMG00000014598 +11330 CTRC MIM:601405|HGNC:HGNC:2523|Ensembl:ENSG00000162438|Vega:OTTHUMG00000002255 +11331 PHB2 MIM:610704|HGNC:HGNC:30306|Ensembl:ENSG00000215021|Vega:OTTHUMG00000168519 +11332 ACOT7 MIM:602587|HGNC:HGNC:24157|Ensembl:ENSG00000097021|Vega:OTTHUMG00000001295 +11333 PDAP1 MIM:607075|HGNC:HGNC:14634|Ensembl:ENSG00000106244|Vega:OTTHUMG00000154629 +11334 TUSC2 MIM:607052|HGNC:HGNC:17034|Ensembl:ENSG00000114383|Vega:OTTHUMG00000156877 +11335 CBX3 MIM:604477|HGNC:HGNC:1553|Ensembl:ENSG00000122565|Vega:OTTHUMG00000022911 +11336 EXOC3 MIM:608186|HGNC:HGNC:30378|Ensembl:ENSG00000180104|Vega:OTTHUMG00000162205 +11337 GABARAP MIM:605125|HGNC:HGNC:4067|Ensembl:ENSG00000170296|Vega:OTTHUMG00000102156 +11338 U2AF2 MIM:191318|HGNC:HGNC:23156|Ensembl:ENSG00000063244|Vega:OTTHUMG00000180908 +11339 OIP5 MIM:606020|HGNC:HGNC:20300|Ensembl:ENSG00000104147|Vega:OTTHUMG00000130251 +11340 EXOSC8 MIM:606019|HGNC:HGNC:17035|Ensembl:ENSG00000120699|Vega:OTTHUMG00000016742 +11341 SCRG1 MIM:603163|HGNC:HGNC:17036|Ensembl:ENSG00000164106|Vega:OTTHUMG00000161249 +11342 RNF13 MIM:609247|HGNC:HGNC:10057|Ensembl:ENSG00000082996|Vega:OTTHUMG00000150338 +11343 MGLL MIM:609699|HGNC:HGNC:17038|Ensembl:ENSG00000074416|Vega:OTTHUMG00000159641 +11344 TWF2 MIM:607433|HGNC:HGNC:9621|Ensembl:ENSG00000247596|Vega:OTTHUMG00000158105 +11345 GABARAPL2 MIM:607452|HGNC:HGNC:13291|Ensembl:ENSG00000034713|Vega:OTTHUMG00000137613 +11346 SYNPO MIM:608155|HGNC:HGNC:30672|Ensembl:ENSG00000171992|Vega:OTTHUMG00000130078 +22794 CASC3 MIM:606504|HGNC:HGNC:17040|Ensembl:ENSG00000108349|Vega:OTTHUMG00000133323 +22795 NID2 MIM:605399|HGNC:HGNC:13389|Ensembl:ENSG00000087303|Vega:OTTHUMG00000140298 +22796 COG2 MIM:606974|HGNC:HGNC:6546|Ensembl:ENSG00000135775|Vega:OTTHUMG00000037753 +22797 TFEC MIM:604732|HGNC:HGNC:11754|Ensembl:ENSG00000105967|Vega:OTTHUMG00000023518 +22798 LAMB4 MIM:616380|HGNC:HGNC:6491|Ensembl:ENSG00000091128|Vega:OTTHUMG00000154874 +22800 RRAS2 MIM:600098|HGNC:HGNC:17271|Ensembl:ENSG00000133818|Vega:OTTHUMG00000165756 +22801 ITGA11 MIM:604789|HGNC:HGNC:6136|Ensembl:ENSG00000137809|Vega:OTTHUMG00000172657 +22802 CLCA4 MIM:616857|HGNC:HGNC:2018|Ensembl:ENSG00000016602|Vega:OTTHUMG00000010260 +22803 XRN2 MIM:608851|HGNC:HGNC:12836|Ensembl:ENSG00000088930|Vega:OTTHUMG00000032025 +22806 IKZF3 MIM:606221|HGNC:HGNC:13178|Ensembl:ENSG00000161405|Vega:OTTHUMG00000133250 +22807 IKZF2 MIM:606234|HGNC:HGNC:13177|Ensembl:ENSG00000030419|Vega:OTTHUMG00000133005 +22808 MRAS MIM:608435|HGNC:HGNC:7227|Ensembl:ENSG00000158186|Vega:OTTHUMG00000159888 +22809 ATF5 MIM:606398|HGNC:HGNC:790|Ensembl:ENSG00000169136|Vega:OTTHUMG00000183065 +22811 MBS3 MIM:604185|HGNC:HGNC:6928 +22813 TDGF1P6 HGNC:HGNC:11706 +22814 TDGF1P5 HGNC:HGNC:11705 +22815 TDGF1P4 HGNC:HGNC:11704 +22816 TDGF1P2 HGNC:HGNC:11702 +22817 NR1I4 HGNC:HGNC:7970 +22818 COPZ1 MIM:615472|HGNC:HGNC:2243|Ensembl:ENSG00000111481|Vega:OTTHUMG00000169762 +22820 COPG1 MIM:615525|HGNC:HGNC:2236|Ensembl:ENSG00000181789|Vega:OTTHUMG00000159451 +22821 RASA3 MIM:605182|HGNC:HGNC:20331|Ensembl:ENSG00000185989|Vega:OTTHUMG00000017399 +22822 PHLDA1 MIM:605335|HGNC:HGNC:8933|Ensembl:ENSG00000139289|Vega:OTTHUMG00000169783 +22823 MTF2 MIM:609882|HGNC:HGNC:29535|Ensembl:ENSG00000143033|Vega:OTTHUMG00000010161 +22824 HSPA4L HGNC:HGNC:17041|Ensembl:ENSG00000164070|Vega:OTTHUMG00000133302 +22826 DNAJC8 HGNC:HGNC:15470|Ensembl:ENSG00000126698|Vega:OTTHUMG00000003538 +22827 PUF60 MIM:604819|HGNC:HGNC:17042|Ensembl:ENSG00000179950|Vega:OTTHUMG00000165155 +22828 SCAF8 MIM:616024|HGNC:HGNC:20959|Ensembl:ENSG00000213079|Vega:OTTHUMG00000015877 +22829 NLGN4Y MIM:400028|HGNC:HGNC:15529|Ensembl:ENSG00000165246|Vega:OTTHUMG00000036618 +22832 CEP162 MIM:610201|HGNC:HGNC:21107|Ensembl:ENSG00000135315|Vega:OTTHUMG00000015123 +22834 ZNF652 MIM:613907|HGNC:HGNC:29147|Ensembl:ENSG00000198740|Vega:OTTHUMG00000161322 +22835 ZFP30 MIM:617317|HGNC:HGNC:29555|Ensembl:ENSG00000120784|Vega:OTTHUMG00000048177 +22836 RHOBTB3 MIM:607353|HGNC:HGNC:18757|Ensembl:ENSG00000164292|Vega:OTTHUMG00000121171 +22837 COBLL1 MIM:610318|HGNC:HGNC:23571|Ensembl:ENSG00000082438|Vega:OTTHUMG00000074019 +22838 RNF44 HGNC:HGNC:19180|Ensembl:ENSG00000146083|Vega:OTTHUMG00000130664 +22839 DLGAP4 MIM:616191|HGNC:HGNC:24476|Ensembl:ENSG00000080845|Vega:OTTHUMG00000032390 +22841 RAB11FIP2 MIM:608599|HGNC:HGNC:29152|Ensembl:ENSG00000107560|Vega:OTTHUMG00000019128 +22843 PPM1E HGNC:HGNC:19322|Ensembl:ENSG00000175175|Vega:OTTHUMG00000179248 +22844 FRMPD1 MIM:616919|HGNC:HGNC:29159|Ensembl:ENSG00000070601|Vega:OTTHUMG00000019927 +22845 DOLK MIM:610746|HGNC:HGNC:23406|Ensembl:ENSG00000175283|Vega:OTTHUMG00000020765 +22846 VASH1 MIM:609011|HGNC:HGNC:19964|Ensembl:ENSG00000071246|Vega:OTTHUMG00000171493 +22847 ZNF507 HGNC:HGNC:23783|Ensembl:ENSG00000168813|Vega:OTTHUMG00000180220 +22848 AAK1 MIM:616405|HGNC:HGNC:19679|Ensembl:ENSG00000115977|Vega:OTTHUMG00000129648 +22849 CPEB3 MIM:610606|HGNC:HGNC:21746|Ensembl:ENSG00000107864|Vega:OTTHUMG00000018756 +22850 ADNP2 MIM:617422|HGNC:HGNC:23803|Ensembl:ENSG00000101544|Vega:OTTHUMG00000172535 +22852 ANKRD26 MIM:610855|HGNC:HGNC:29186|Ensembl:ENSG00000107890|Vega:OTTHUMG00000017851 +22853 LMTK2 MIM:610989|HGNC:HGNC:17880|Ensembl:ENSG00000164715|Vega:OTTHUMG00000154256 +22854 NTNG1 MIM:608818|HGNC:HGNC:23319|Ensembl:ENSG00000162631|Vega:OTTHUMG00000010965 +22856 CHSY1 MIM:608183|HGNC:HGNC:17198|Ensembl:ENSG00000131873|Vega:OTTHUMG00000149873 +22858 ICK MIM:612325|HGNC:HGNC:21219|Ensembl:ENSG00000112144|Vega:OTTHUMG00000014870 +22859 ADGRL1 MIM:616416|HGNC:HGNC:20973|Ensembl:ENSG00000072071|Vega:OTTHUMG00000182138 +22861 NLRP1 MIM:606636|HGNC:HGNC:14374|Ensembl:ENSG00000091592|Vega:OTTHUMG00000132419 +22862 FNDC3A MIM:615794|HGNC:HGNC:20296|Ensembl:ENSG00000102531|Vega:OTTHUMG00000016911 +22863 ATG14 MIM:613515|HGNC:HGNC:19962|Ensembl:ENSG00000126775|Vega:OTTHUMG00000172129 +22864 R3HDM2 HGNC:HGNC:29167|Ensembl:ENSG00000179912|Vega:OTTHUMG00000171568 +22865 SLITRK3 MIM:609679|HGNC:HGNC:23501|Ensembl:ENSG00000121871|Vega:OTTHUMG00000158072 +22866 CNKSR2 MIM:300724|HGNC:HGNC:19701|Ensembl:ENSG00000149970|Vega:OTTHUMG00000021233 +22868 FASTKD2 MIM:612322|HGNC:HGNC:29160|Ensembl:ENSG00000118246|Vega:OTTHUMG00000132917 +22869 ZNF510 HGNC:HGNC:29161|Ensembl:ENSG00000081386|Vega:OTTHUMG00000020303 +22870 PPP6R1 MIM:610875|HGNC:HGNC:29195|Ensembl:ENSG00000105063|Vega:OTTHUMG00000180704 +22871 NLGN1 MIM:600568|HGNC:HGNC:14291|Ensembl:ENSG00000169760|Vega:OTTHUMG00000157005 +22872 SEC31A MIM:610257|HGNC:HGNC:17052|Ensembl:ENSG00000138674|Vega:OTTHUMG00000130297 +22873 DZIP1 MIM:608671|HGNC:HGNC:20908|Ensembl:ENSG00000134874|Vega:OTTHUMG00000017224 +22874 PLEKHA6 MIM:607771|HGNC:HGNC:17053|Ensembl:ENSG00000143850|Vega:OTTHUMG00000036057 +22875 ENPP4 MIM:617000|HGNC:HGNC:3359|Ensembl:ENSG00000001561|Vega:OTTHUMG00000014779 +22876 INPP5F MIM:609389|HGNC:HGNC:17054|Ensembl:ENSG00000198825|Vega:OTTHUMG00000019158 +22877 MLXIP MIM:608090|HGNC:HGNC:17055|Ensembl:ENSG00000175727|Vega:OTTHUMG00000168953 +22878 TRAPPC8 MIM:614136|HGNC:HGNC:29169|Ensembl:ENSG00000153339|Vega:OTTHUMG00000132267 +22879 MON1B MIM:608954|HGNC:HGNC:25020|Ensembl:ENSG00000103111|Vega:OTTHUMG00000137618 +22880 MORC2 MIM:616661|HGNC:HGNC:23573|Ensembl:ENSG00000133422|Vega:OTTHUMG00000151193 +22881 ANKRD6 MIM:610583|HGNC:HGNC:17280|Ensembl:ENSG00000135299|Vega:OTTHUMG00000015202 +22882 ZHX2 MIM:609185|HGNC:HGNC:18513|Ensembl:ENSG00000178764|Vega:OTTHUMG00000165077 +22883 CLSTN1 MIM:611321|HGNC:HGNC:17447|Ensembl:ENSG00000171603|Vega:OTTHUMG00000001451 +22884 WDR37 HGNC:HGNC:31406|Ensembl:ENSG00000047056|Vega:OTTHUMG00000017540 +22885 ABLIM3 MIM:611305|HGNC:HGNC:29132|Ensembl:ENSG00000173210|Vega:OTTHUMG00000129932 +22887 FOXJ3 MIM:616035|HGNC:HGNC:29178|Ensembl:ENSG00000198815|Vega:OTTHUMG00000007026 +22888 UBOX5 HGNC:HGNC:17777|Ensembl:ENSG00000185019|Vega:OTTHUMG00000031731 +22889 KIAA0907 HGNC:HGNC:29145|Ensembl:ENSG00000132680|Vega:OTTHUMG00000014103 +22890 ZBTB1 MIM:616578|HGNC:HGNC:20259|Ensembl:ENSG00000126804|Vega:OTTHUMG00000171147 +22891 ZNF365 MIM:607818|HGNC:HGNC:18194|Ensembl:ENSG00000138311|Vega:OTTHUMG00000018302 +22893 BAHD1 MIM:613880|HGNC:HGNC:29153|Ensembl:ENSG00000140320|Vega:OTTHUMG00000129982 +22894 DIS3 MIM:607533|HGNC:HGNC:20604|Ensembl:ENSG00000083520|Vega:OTTHUMG00000017070 +22895 RPH3A MIM:612159|HGNC:HGNC:17056|Ensembl:ENSG00000089169|Vega:OTTHUMG00000169713 +22897 CEP164 MIM:614848|HGNC:HGNC:29182|Ensembl:ENSG00000110274|Vega:OTTHUMG00000167070 +22898 DENND3 MIM:617503|HGNC:HGNC:29134|Ensembl:ENSG00000105339|Vega:OTTHUMG00000164775 +22899 ARHGEF15 MIM:608504|HGNC:HGNC:15590|Ensembl:ENSG00000198844|Vega:OTTHUMG00000108187 +22900 CARD8 MIM:609051|HGNC:HGNC:17057|Ensembl:ENSG00000105483|Vega:OTTHUMG00000165047 +22901 ARSG MIM:610008|HGNC:HGNC:24102|Ensembl:ENSG00000141337|Vega:OTTHUMG00000179810 +22902 RUFY3 MIM:611194|HGNC:HGNC:30285|Ensembl:ENSG00000018189|Vega:OTTHUMG00000129910 +22903 BTBD3 MIM:615566|HGNC:HGNC:15854|Ensembl:ENSG00000132640|Vega:OTTHUMG00000031889 +22904 SBNO2 MIM:615729|HGNC:HGNC:29158|Ensembl:ENSG00000064932|Vega:OTTHUMG00000181875 +22905 EPN2 MIM:607263|HGNC:HGNC:18639|Ensembl:ENSG00000072134|Vega:OTTHUMG00000187034 +22906 TRAK1 MIM:608112|HGNC:HGNC:29947|Ensembl:ENSG00000182606|Vega:OTTHUMG00000131795 +22907 DHX30 MIM:616423|HGNC:HGNC:16716|Ensembl:ENSG00000132153|Vega:OTTHUMG00000133522 +22908 SACM1L MIM:606569|HGNC:HGNC:17059|Ensembl:ENSG00000211456|Vega:OTTHUMG00000156653 +22909 FAN1 MIM:613534|HGNC:HGNC:29170|Ensembl:ENSG00000198690|Vega:OTTHUMG00000175661 +22911 WDR47 MIM:615734|HGNC:HGNC:29141|Ensembl:ENSG00000085433|Vega:OTTHUMG00000011734 +22913 RALY MIM:614663|HGNC:HGNC:15921|Ensembl:ENSG00000125970|Vega:OTTHUMG00000032283 +22914 KLRK1 MIM:611817|HGNC:HGNC:18788|Ensembl:ENSG00000213809|Vega:OTTHUMG00000168574 +22915 MMRN1 MIM:601456|HGNC:HGNC:7178|Ensembl:ENSG00000138722|Vega:OTTHUMG00000130947 +22916 NCBP2 MIM:605133|HGNC:HGNC:7659|Ensembl:ENSG00000114503|Vega:OTTHUMG00000155520 +22917 ZP1 MIM:195000|HGNC:HGNC:13187|Ensembl:ENSG00000149506|Vega:OTTHUMG00000167797 +22918 CD93 MIM:120577|HGNC:HGNC:15855|Ensembl:ENSG00000125810|Vega:OTTHUMG00000032058 +22919 MAPRE1 MIM:603108|HGNC:HGNC:6890|Ensembl:ENSG00000101367|Vega:OTTHUMG00000032228 +22920 KIFAP3 MIM:601836|HGNC:HGNC:17060|Ensembl:ENSG00000075945|Vega:OTTHUMG00000035947 +22921 MSRB2 MIM:613782|HGNC:HGNC:17061|Ensembl:ENSG00000148450|Vega:OTTHUMG00000017812 +22924 MAPRE3 MIM:605788|HGNC:HGNC:6892|Ensembl:ENSG00000084764|Vega:OTTHUMG00000097067 +22925 PLA2R1 MIM:604939|HGNC:HGNC:9042|Ensembl:ENSG00000153246|Vega:OTTHUMG00000154087 +22926 ATF6 MIM:605537|HGNC:HGNC:791|Ensembl:ENSG00000118217|Vega:OTTHUMG00000023961 +22927 HABP4 MIM:617369|HGNC:HGNC:17062|Ensembl:ENSG00000130956|Vega:OTTHUMG00000020298 +22928 SEPHS2 MIM:606218|HGNC:HGNC:19686|Ensembl:ENSG00000179918|Vega:OTTHUMG00000176988 +22929 SEPHS1 MIM:600902|HGNC:HGNC:19685|Ensembl:ENSG00000086475|Vega:OTTHUMG00000017696 +22930 RAB3GAP1 MIM:602536|HGNC:HGNC:17063|Ensembl:ENSG00000115839|Vega:OTTHUMG00000154889 +22931 RAB18 MIM:602207|HGNC:HGNC:14244|Ensembl:ENSG00000099246|Vega:OTTHUMG00000017861 +22932 POMZP3 MIM:600587|HGNC:HGNC:9203|Ensembl:ENSG00000146707|Vega:OTTHUMG00000023514 +22933 SIRT2 MIM:604480|HGNC:HGNC:10886|Ensembl:ENSG00000068903 +22934 RPIA MIM:180430|HGNC:HGNC:10297|Ensembl:ENSG00000153574|Vega:OTTHUMG00000130333 +22936 ELL2 MIM:601874|HGNC:HGNC:17064|Ensembl:ENSG00000118985|Vega:OTTHUMG00000122085 +22937 SCAP MIM:601510|HGNC:HGNC:30634|Ensembl:ENSG00000114650|Vega:OTTHUMG00000125539 +22938 SNW1 MIM:603055|HGNC:HGNC:16696|Ensembl:ENSG00000100603|Vega:OTTHUMG00000171527 +22941 SHANK2 MIM:603290|HGNC:HGNC:14295|Ensembl:ENSG00000162105|Vega:OTTHUMG00000154615 +22943 DKK1 MIM:605189|HGNC:HGNC:2891|Ensembl:ENSG00000107984|Vega:OTTHUMG00000018247 +22944 KIN MIM:601720|HGNC:HGNC:6327|Ensembl:ENSG00000151657|Vega:OTTHUMG00000017634 +22945 GPAA1P1 HGNC:HGNC:4447 +22947 DUX4L1 HGNC:HGNC:3082 +22948 CCT5 MIM:610150|HGNC:HGNC:1618|Ensembl:ENSG00000150753|Vega:OTTHUMG00000131042 +22949 PTGR1 MIM:601274|HGNC:HGNC:18429|Ensembl:ENSG00000106853|Vega:OTTHUMG00000020493 +22950 SLC4A1AP MIM:602655|HGNC:HGNC:13813|Ensembl:ENSG00000163798|Vega:OTTHUMG00000151944 +22952 CYP2G1P MIM:601133|HGNC:HGNC:2633|Ensembl:ENSG00000130612 +22953 P2RX2 MIM:600844|HGNC:HGNC:15459|Ensembl:ENSG00000187848|Vega:OTTHUMG00000168018 +22954 TRIM32 MIM:602290|HGNC:HGNC:16380|Ensembl:ENSG00000119401|Vega:OTTHUMG00000021026 +22955 SCMH1 MIM:616396|HGNC:HGNC:19003|Ensembl:ENSG00000010803|Vega:OTTHUMG00000005720 +22969 RPL41P3 HGNC:HGNC:10358 +22970 RPL41P2 HGNC:HGNC:10357 +22971 RPL41P1 HGNC:HGNC:10356 +22973 LAMB2P1 HGNC:HGNC:6488 +22974 TPX2 MIM:605917|HGNC:HGNC:1249|Ensembl:ENSG00000088325|Vega:OTTHUMG00000032190 +22976 PAXIP1 MIM:608254|HGNC:HGNC:8624|Ensembl:ENSG00000157212|Vega:OTTHUMG00000151322 +22977 AKR7A3 MIM:608477|HGNC:HGNC:390|Ensembl:ENSG00000162482|Vega:OTTHUMG00000002523 +22978 NT5C2 MIM:600417|HGNC:HGNC:8022|Ensembl:ENSG00000076685|Vega:OTTHUMG00000018981 +22979 EFR3B MIM:616797|HGNC:HGNC:29155|Ensembl:ENSG00000084710|Vega:OTTHUMG00000151988 +22980 TCF25 MIM:612326|HGNC:HGNC:29181|Ensembl:ENSG00000141002|Vega:OTTHUMG00000138986 +22981 NINL MIM:609580|HGNC:HGNC:29163|Ensembl:ENSG00000101004|Vega:OTTHUMG00000032127 +22982 DIP2C MIM:611380|HGNC:HGNC:29150|Ensembl:ENSG00000151240|Vega:OTTHUMG00000017532 +22983 MAST1 MIM:612256|HGNC:HGNC:19034|Ensembl:ENSG00000105613|Vega:OTTHUMG00000180514 +22984 PDCD11 MIM:612333|HGNC:HGNC:13408|Ensembl:ENSG00000148843|Vega:OTTHUMG00000018988 +22985 ACIN1 MIM:604562|HGNC:HGNC:17066|Ensembl:ENSG00000100813|Vega:OTTHUMG00000028716 +22986 SORCS3 MIM:606285|HGNC:HGNC:16699|Ensembl:ENSG00000156395|Vega:OTTHUMG00000019011 +22987 SV2C MIM:610291|HGNC:HGNC:30670|Ensembl:ENSG00000122012|Vega:OTTHUMG00000162384 +22989 MYH15 MIM:609929|HGNC:HGNC:31073|Ensembl:ENSG00000144821|Vega:OTTHUMG00000159226 +22990 PCNX1 HGNC:HGNC:19740|Ensembl:ENSG00000100731|Vega:OTTHUMG00000171242 +22992 KDM2A MIM:605657|HGNC:HGNC:13606|Ensembl:ENSG00000173120|Vega:OTTHUMG00000167103 +22993 HMGXB3 HGNC:HGNC:28982|Ensembl:ENSG00000113716|Vega:OTTHUMG00000163493 +22994 CEP131 MIM:613479|HGNC:HGNC:29511|Ensembl:ENSG00000141577|Vega:OTTHUMG00000132728 +22995 CEP152 MIM:613529|HGNC:HGNC:29298|Ensembl:ENSG00000103995|Vega:OTTHUMG00000172219 +22996 TTC39A HGNC:HGNC:18657|Ensembl:ENSG00000085831|Vega:OTTHUMG00000008193 +22997 IGSF9B MIM:613773|HGNC:HGNC:32326|Ensembl:ENSG00000080854|Vega:OTTHUMG00000167124 +22998 LIMCH1 HGNC:HGNC:29191|Ensembl:ENSG00000064042|Vega:OTTHUMG00000160575 +22999 RIMS1 MIM:606629|HGNC:HGNC:17282|Ensembl:ENSG00000079841|Vega:OTTHUMG00000015009 +23001 WDFY3 MIM:617485|HGNC:HGNC:20751|Ensembl:ENSG00000163625|Vega:OTTHUMG00000130424 +23002 DAAM1 MIM:606626|HGNC:HGNC:18142|Ensembl:ENSG00000100592|Vega:OTTHUMG00000140326 +23005 MAPKBP1 MIM:616786|HGNC:HGNC:29536|Ensembl:ENSG00000137802|Vega:OTTHUMG00000160227 +23007 PLCH1 MIM:612835|HGNC:HGNC:29185|Ensembl:ENSG00000114805|Vega:OTTHUMG00000158477 +23008 KLHDC10 MIM:615152|HGNC:HGNC:22194|Ensembl:ENSG00000128607|Vega:OTTHUMG00000157654 +23011 RAB21 MIM:612398|HGNC:HGNC:18263|Ensembl:ENSG00000080371|Vega:OTTHUMG00000169572 +23012 STK38L MIM:615836|HGNC:HGNC:17848|Ensembl:ENSG00000211455|Vega:OTTHUMG00000169284 +23013 SPEN MIM:613484|HGNC:HGNC:17575|Ensembl:ENSG00000065526|Vega:OTTHUMG00000009376 +23014 FBXO21 MIM:609095|HGNC:HGNC:13592|Ensembl:ENSG00000135108|Vega:OTTHUMG00000169495 +23015 GOLGA8A MIM:616180|HGNC:HGNC:31972|Ensembl:ENSG00000175265|Vega:OTTHUMG00000129447 +23016 EXOSC7 MIM:606488|HGNC:HGNC:28112|Ensembl:ENSG00000075914|Vega:OTTHUMG00000133095 +23017 FAIM2 MIM:604306|HGNC:HGNC:17067|Ensembl:ENSG00000135472|Vega:OTTHUMG00000169808 +23019 CNOT1 MIM:604917|HGNC:HGNC:7877|Ensembl:ENSG00000125107|Vega:OTTHUMG00000133487 +23020 SNRNP200 MIM:601664|HGNC:HGNC:30859|Ensembl:ENSG00000144028|Vega:OTTHUMG00000130455 +23022 PALLD MIM:608092|HGNC:HGNC:17068|Ensembl:ENSG00000129116|Vega:OTTHUMG00000161097 +23023 TMCC1 MIM:616242|HGNC:HGNC:29116|Ensembl:ENSG00000172765|Vega:OTTHUMG00000159579 +23024 PDZRN3 MIM:609729|HGNC:HGNC:17704|Ensembl:ENSG00000121440|Vega:OTTHUMG00000158865 +23025 UNC13A MIM:609894|HGNC:HGNC:23150|Ensembl:ENSG00000130477|Vega:OTTHUMG00000163877 +23026 MYO16 MIM:615479|HGNC:HGNC:29822|Ensembl:ENSG00000041515 +23028 KDM1A MIM:609132|HGNC:HGNC:29079|Ensembl:ENSG00000004487|Vega:OTTHUMG00000003220 +23029 RBM34 HGNC:HGNC:28965|Ensembl:ENSG00000188739|Vega:OTTHUMG00000039620 +23030 KDM4B MIM:609765|HGNC:HGNC:29136|Ensembl:ENSG00000127663|Vega:OTTHUMG00000180281 +23031 MAST3 MIM:612258|HGNC:HGNC:19036|Ensembl:ENSG00000099308|Vega:OTTHUMG00000183418 +23032 USP33 MIM:615146|HGNC:HGNC:20059|Ensembl:ENSG00000077254|Vega:OTTHUMG00000009651 +23033 DOPEY1 MIM:616823|HGNC:HGNC:21194|Ensembl:ENSG00000083097|Vega:OTTHUMG00000016365 +23034 SAMD4A MIM:610747|HGNC:HGNC:23023|Ensembl:ENSG00000020577|Vega:OTTHUMG00000170999 +23035 PHLPP2 MIM:611066|HGNC:HGNC:29149|Ensembl:ENSG00000040199|Vega:OTTHUMG00000176867 +23036 ZNF292 MIM:616213|HGNC:HGNC:18410|Ensembl:ENSG00000188994|Vega:OTTHUMG00000015164 +23037 PDZD2 MIM:610697|HGNC:HGNC:18486|Ensembl:ENSG00000133401|Vega:OTTHUMG00000161981 +23038 WDTC1 HGNC:HGNC:29175|Ensembl:ENSG00000142784|Vega:OTTHUMG00000004273 +23039 XPO7 MIM:606140|HGNC:HGNC:14108|Ensembl:ENSG00000130227|Vega:OTTHUMG00000163789 +23040 MYT1L MIM:613084|HGNC:HGNC:7623|Ensembl:ENSG00000186487|Vega:OTTHUMG00000151407 +23041 MON2 MIM:616822|HGNC:HGNC:29177|Ensembl:ENSG00000061987|Vega:OTTHUMG00000169992 +23042 PDXDC1 MIM:614244|HGNC:HGNC:28995|Ensembl:ENSG00000179889|Vega:OTTHUMG00000166304 +23043 TNIK MIM:610005|HGNC:HGNC:30765|Ensembl:ENSG00000154310|Vega:OTTHUMG00000159036 +23046 KIF21B MIM:608322|HGNC:HGNC:29442|Ensembl:ENSG00000116852|Vega:OTTHUMG00000035787 +23047 PDS5B MIM:605333|HGNC:HGNC:20418|Ensembl:ENSG00000083642|Vega:OTTHUMG00000016704 +23048 FNBP1 MIM:606191|HGNC:HGNC:17069|Ensembl:ENSG00000187239|Vega:OTTHUMG00000020800 +23049 SMG1 MIM:607032|HGNC:HGNC:30045|Ensembl:ENSG00000157106|Vega:OTTHUMG00000166900 +23051 ZHX3 MIM:609598|HGNC:HGNC:15935|Ensembl:ENSG00000174306|Vega:OTTHUMG00000032481 +23052 ENDOD1 HGNC:HGNC:29129|Ensembl:ENSG00000149218|Vega:OTTHUMG00000167835 +23053 ZSWIM8 HGNC:HGNC:23528|Ensembl:ENSG00000214655|Vega:OTTHUMG00000018486 +23054 NCOA6 MIM:605299|HGNC:HGNC:15936|Ensembl:ENSG00000198646|Vega:OTTHUMG00000032311 +23057 NMNAT2 MIM:608701|HGNC:HGNC:16789|Ensembl:ENSG00000157064|Vega:OTTHUMG00000035519 +23059 CLUAP1 MIM:616787|HGNC:HGNC:19009|Ensembl:ENSG00000103351|Vega:OTTHUMG00000177581 +23060 ZNF609 MIM:617474|HGNC:HGNC:29003|Ensembl:ENSG00000180357|Vega:OTTHUMG00000172370 +23061 TBC1D9B HGNC:HGNC:29097|Ensembl:ENSG00000197226|Vega:OTTHUMG00000130911 +23062 GGA2 MIM:606005|HGNC:HGNC:16064|Ensembl:ENSG00000103365|Vega:OTTHUMG00000096957 +23063 WAPL MIM:610754|HGNC:HGNC:23293|Ensembl:ENSG00000062650|Vega:OTTHUMG00000018651 +23064 SETX MIM:608465|HGNC:HGNC:445|Ensembl:ENSG00000107290|Vega:OTTHUMG00000020834 +23065 EMC1 MIM:616846|HGNC:HGNC:28957|Ensembl:ENSG00000127463|Vega:OTTHUMG00000002497 +23066 CAND2 MIM:610403|HGNC:HGNC:30689|Ensembl:ENSG00000144712|Vega:OTTHUMG00000155397 +23067 SETD1B MIM:611055|HGNC:HGNC:29187|Ensembl:ENSG00000139718|Vega:OTTHUMG00000169080 +23070 CMTR1 MIM:616189|HGNC:HGNC:21077|Ensembl:ENSG00000137200|Vega:OTTHUMG00000014624 +23071 ERP44 MIM:609170|HGNC:HGNC:18311|Ensembl:ENSG00000023318|Vega:OTTHUMG00000020363 +23072 HECW1 MIM:610384|HGNC:HGNC:22195|Ensembl:ENSG00000002746|Vega:OTTHUMG00000128917 +23074 UHRF1BP1L HGNC:HGNC:29102|Ensembl:ENSG00000111647|Vega:OTTHUMG00000170195 +23075 SWAP70 MIM:604762|HGNC:HGNC:17070|Ensembl:ENSG00000133789|Vega:OTTHUMG00000165865 +23076 RRP1B MIM:610654|HGNC:HGNC:23818|Ensembl:ENSG00000160208|Vega:OTTHUMG00000086872 +23077 MYCBP2 MIM:610392|HGNC:HGNC:23386|Ensembl:ENSG00000005810|Vega:OTTHUMG00000017105 +23078 VWA8 MIM:617509|HGNC:HGNC:29071|Ensembl:ENSG00000102763|Vega:OTTHUMG00000016799 +23080 AVL9 MIM:612927|HGNC:HGNC:28994|Ensembl:ENSG00000105778|Vega:OTTHUMG00000152929 +23081 KDM4C MIM:605469|HGNC:HGNC:17071|Ensembl:ENSG00000107077|Vega:OTTHUMG00000019536|Vega:OTTHUMG00000187508 +23082 PPRC1 MIM:617462|HGNC:HGNC:30025|Ensembl:ENSG00000148840|Vega:OTTHUMG00000018948 +23085 ERC1 MIM:607127|HGNC:HGNC:17072|Ensembl:ENSG00000082805 +23086 EXPH5 MIM:612878|HGNC:HGNC:30578|Ensembl:ENSG00000110723|Vega:OTTHUMG00000166536 +23087 TRIM35 MIM:617007|HGNC:HGNC:16285|Ensembl:ENSG00000104228|Vega:OTTHUMG00000102047 +23089 PEG10 MIM:609810|HGNC:HGNC:14005|Ensembl:ENSG00000242265|Vega:OTTHUMG00000155578 +23090 ZNF423 MIM:604557|HGNC:HGNC:16762|Ensembl:ENSG00000102935|Vega:OTTHUMG00000173491 +23091 ZC3H13 MIM:616453|HGNC:HGNC:20368|Ensembl:ENSG00000123200|Vega:OTTHUMG00000016863 +23092 ARHGAP26 MIM:605370|HGNC:HGNC:17073|Ensembl:ENSG00000145819|Vega:OTTHUMG00000059705 +23093 TTLL5 MIM:612268|HGNC:HGNC:19963|Ensembl:ENSG00000119685|Vega:OTTHUMG00000171611 +23094 SIPA1L3 MIM:616655|HGNC:HGNC:23801|Ensembl:ENSG00000105738|Vega:OTTHUMG00000073727 +23095 KIF1B MIM:605995|HGNC:HGNC:16636|Ensembl:ENSG00000054523|Vega:OTTHUMG00000001817 +23096 IQSEC2 MIM:300522|HGNC:HGNC:29059|Ensembl:ENSG00000124313|Vega:OTTHUMG00000021608 +23097 CDK19 MIM:614720|HGNC:HGNC:19338|Ensembl:ENSG00000155111|Vega:OTTHUMG00000015365 +23098 SARM1 MIM:607732|HGNC:HGNC:17074|Ensembl:ENSG00000004139|Vega:OTTHUMG00000132499 +23099 ZBTB43 HGNC:HGNC:17908|Ensembl:ENSG00000169155|Vega:OTTHUMG00000020693 +23101 MCF2L2 HGNC:HGNC:30319|Ensembl:ENSG00000053524|Vega:OTTHUMG00000158388 +23102 TBC1D2B HGNC:HGNC:29183|Ensembl:ENSG00000167202|Vega:OTTHUMG00000152885 +23105 FSTL4 HGNC:HGNC:21389|Ensembl:ENSG00000053108|Vega:OTTHUMG00000162729 +23107 MRPS27 MIM:611989|HGNC:HGNC:14512|Ensembl:ENSG00000113048|Vega:OTTHUMG00000100951 +23108 RAP1GAP2 HGNC:HGNC:29176|Ensembl:ENSG00000132359|Vega:OTTHUMG00000177642 +23109 DDN MIM:610588|HGNC:HGNC:24458|Ensembl:ENSG00000181418|Vega:OTTHUMG00000156183 +23111 SPART MIM:607111|HGNC:HGNC:18514|Ensembl:ENSG00000133104|Vega:OTTHUMG00000016730 +23112 TNRC6B MIM:610740|HGNC:HGNC:29190|Ensembl:ENSG00000100354|Vega:OTTHUMG00000151114 +23113 CUL9 MIM:607489|HGNC:HGNC:15982|Ensembl:ENSG00000112659|Vega:OTTHUMG00000014723 +23114 NFASC MIM:609145|HGNC:HGNC:29866|Ensembl:ENSG00000163531|Vega:OTTHUMG00000151697 +23116 TOGARAM1 HGNC:HGNC:19959|Ensembl:ENSG00000198718|Vega:OTTHUMG00000140264 +23117 NPIPB3 HGNC:HGNC:28989 +23118 TAB2 MIM:605101|HGNC:HGNC:17075|Ensembl:ENSG00000055208|Ensembl:ENSG00000228408|Vega:OTTHUMG00000015783 +23119 HIC2 MIM:607712|HGNC:HGNC:18595|Ensembl:ENSG00000169635|Vega:OTTHUMG00000150781 +23120 ATP10B HGNC:HGNC:13543|Ensembl:ENSG00000118322|Vega:OTTHUMG00000163551 +23122 CLASP2 MIM:605853|HGNC:HGNC:17078|Ensembl:ENSG00000163539|Vega:OTTHUMG00000156489 +23125 CAMTA2 MIM:611508|HGNC:HGNC:18807|Ensembl:ENSG00000108509|Vega:OTTHUMG00000099417 +23126 POGZ MIM:614787|HGNC:HGNC:18801|Ensembl:ENSG00000143442|Vega:OTTHUMG00000012499 +23127 COLGALT2 MIM:617533|HGNC:HGNC:16790|Ensembl:ENSG00000198756|Vega:OTTHUMG00000035460 +23129 PLXND1 MIM:604282|HGNC:HGNC:9107|Ensembl:ENSG00000004399|Vega:OTTHUMG00000159547 +23130 ATG2A MIM:616225|HGNC:HGNC:29028|Ensembl:ENSG00000110046|Vega:OTTHUMG00000066831 +23131 GPATCH8 MIM:614396|HGNC:HGNC:29066|Ensembl:ENSG00000186566|Vega:OTTHUMG00000181818 +23132 RAD54L2 HGNC:HGNC:29123|Ensembl:ENSG00000164080|Vega:OTTHUMG00000152936 +23133 PHF8 MIM:300560|HGNC:HGNC:20672|Ensembl:ENSG00000172943|Vega:OTTHUMG00000021622 +23135 KDM6B MIM:611577|HGNC:HGNC:29012|Ensembl:ENSG00000132510|Vega:OTTHUMG00000178021 +23136 EPB41L3 MIM:605331|HGNC:HGNC:3380|Ensembl:ENSG00000082397|Vega:OTTHUMG00000131562 +23137 SMC5 MIM:609386|HGNC:HGNC:20465|Ensembl:ENSG00000198887|Vega:OTTHUMG00000019992 +23138 N4BP3 HGNC:HGNC:29852|Ensembl:ENSG00000145911|Vega:OTTHUMG00000163456 +23139 MAST2 MIM:612257|HGNC:HGNC:19035|Ensembl:ENSG00000086015|Vega:OTTHUMG00000008007 +23140 ZZEF1 HGNC:HGNC:29027|Ensembl:ENSG00000074755|Vega:OTTHUMG00000090741 +23141 ANKLE2 MIM:616062|HGNC:HGNC:29101|Ensembl:ENSG00000176915|Vega:OTTHUMG00000168046 +23142 DCUN1D4 MIM:612977|HGNC:HGNC:28998|Ensembl:ENSG00000109184|Vega:OTTHUMG00000128700 +23143 LRCH1 MIM:610368|HGNC:HGNC:20309|Ensembl:ENSG00000136141|Vega:OTTHUMG00000016877 +23144 ZC3H3 HGNC:HGNC:28972|Ensembl:ENSG00000014164|Vega:OTTHUMG00000165127 +23145 SSPO MIM:617356|HGNC:HGNC:21998|Ensembl:ENSG00000197558 +23148 NACAD HGNC:HGNC:22196|Ensembl:ENSG00000136274|Vega:OTTHUMG00000159170 +23149 FCHO1 MIM:613437|HGNC:HGNC:29002|Ensembl:ENSG00000130475|Vega:OTTHUMG00000183293 +23150 FRMD4B MIM:617467|HGNC:HGNC:24886|Ensembl:ENSG00000114541|Vega:OTTHUMG00000158772 +23151 GRAMD4 MIM:613691|HGNC:HGNC:29113|Ensembl:ENSG00000075240|Vega:OTTHUMG00000150402 +23152 CIC MIM:612082|HGNC:HGNC:14214|Ensembl:ENSG00000079432|Vega:OTTHUMG00000182794 +23154 NCDN MIM:608458|HGNC:HGNC:17597|Ensembl:ENSG00000020129|Vega:OTTHUMG00000059204 +23155 CLCC1 MIM:617539|HGNC:HGNC:29675|Ensembl:ENSG00000121940|Vega:OTTHUMG00000011732 +23157 SEPT6 MIM:300683|HGNC:HGNC:15848|Ensembl:ENSG00000125354|Vega:OTTHUMG00000022280 +23158 TBC1D9 HGNC:HGNC:21710|Ensembl:ENSG00000109436|Vega:OTTHUMG00000161405 +23160 WDR43 MIM:616195|HGNC:HGNC:28945|Ensembl:ENSG00000163811|Vega:OTTHUMG00000152015 +23161 SNX13 MIM:606589|HGNC:HGNC:21335|Ensembl:ENSG00000071189|Vega:OTTHUMG00000152730 +23162 MAPK8IP3 MIM:605431|HGNC:HGNC:6884|Ensembl:ENSG00000138834|Vega:OTTHUMG00000128637 +23163 GGA3 MIM:606006|HGNC:HGNC:17079|Ensembl:ENSG00000125447|Vega:OTTHUMG00000179483 +23164 MPRIP MIM:612935|HGNC:HGNC:30321|Ensembl:ENSG00000133030|Vega:OTTHUMG00000059276 +23165 NUP205 MIM:614352|HGNC:HGNC:18658|Ensembl:ENSG00000155561|Vega:OTTHUMG00000155497 +23166 STAB1 MIM:608560|HGNC:HGNC:18628|Ensembl:ENSG00000010327|Vega:OTTHUMG00000158574 +23167 EFR3A MIM:611798|HGNC:HGNC:28970|Ensembl:ENSG00000132294|Vega:OTTHUMG00000150552 +23168 RTF1 MIM:611633|HGNC:HGNC:28996|Ensembl:ENSG00000137815|Vega:OTTHUMG00000133744 +23169 SLC35D1 MIM:610804|HGNC:HGNC:20800|Ensembl:ENSG00000116704|Vega:OTTHUMG00000009360 +23170 TTLL12 HGNC:HGNC:28974|Ensembl:ENSG00000100304|Vega:OTTHUMG00000150682 +23171 GPD1L MIM:611778|HGNC:HGNC:28956|Ensembl:ENSG00000152642|Vega:OTTHUMG00000155846 +23172 ABRAXAS2 MIM:611144|HGNC:HGNC:28975|Ensembl:ENSG00000165660|Vega:OTTHUMG00000019218 +23173 METAP1 MIM:610151|HGNC:HGNC:15789|Ensembl:ENSG00000164024|Vega:OTTHUMG00000161231 +23174 ZCCHC14 HGNC:HGNC:24134|Ensembl:ENSG00000140948|Vega:OTTHUMG00000137655 +23175 LPIN1 MIM:605518|HGNC:HGNC:13345|Ensembl:ENSG00000134324|Vega:OTTHUMG00000119082 +23176 SEPT8 MIM:608418|HGNC:HGNC:16511|Ensembl:ENSG00000164402|Vega:OTTHUMG00000059735 +23177 CEP68 MIM:616889|HGNC:HGNC:29076|Ensembl:ENSG00000011523|Vega:OTTHUMG00000129538 +23178 PASK MIM:607505|HGNC:HGNC:17270|Ensembl:ENSG00000115687|Vega:OTTHUMG00000133392 +23179 RGL1 MIM:605667|HGNC:HGNC:30281|Ensembl:ENSG00000143344|Vega:OTTHUMG00000035328 +23180 RFTN1 HGNC:HGNC:30278|Ensembl:ENSG00000131378|Vega:OTTHUMG00000156973 +23181 DIP2A MIM:607711|HGNC:HGNC:17217|Ensembl:ENSG00000160305|Vega:OTTHUMG00000090717 +23184 MESD MIM:607783|HGNC:HGNC:13520|Ensembl:ENSG00000117899|Vega:OTTHUMG00000172288 +23185 LARP4B MIM:616513|HGNC:HGNC:28987|Ensembl:ENSG00000107929|Vega:OTTHUMG00000017534 +23186 RCOR1 MIM:607675|HGNC:HGNC:17441|Ensembl:ENSG00000089902|Vega:OTTHUMG00000171778 +23187 PHLDB1 MIM:612834|HGNC:HGNC:23697|Ensembl:ENSG00000019144|Vega:OTTHUMG00000166341 +23189 KANK1 MIM:607704|HGNC:HGNC:19309|Ensembl:ENSG00000107104|Vega:OTTHUMG00000019434 +23190 UBXN4 MIM:611216|HGNC:HGNC:14860|Ensembl:ENSG00000144224|Vega:OTTHUMG00000153577 +23191 CYFIP1 MIM:606322|HGNC:HGNC:13759|Ensembl:ENSG00000273749|Vega:OTTHUMG00000129100 +23192 ATG4B MIM:611338|HGNC:HGNC:20790|Ensembl:ENSG00000168397|Vega:OTTHUMG00000151514 +23193 GANAB MIM:104160|HGNC:HGNC:4138|Ensembl:ENSG00000089597|Vega:OTTHUMG00000167696 +23194 FBXL7 MIM:605656|HGNC:HGNC:13604|Ensembl:ENSG00000183580|Vega:OTTHUMG00000161798 +23195 MDN1 HGNC:HGNC:18302|Ensembl:ENSG00000112159|Vega:OTTHUMG00000015213 +23196 FAM120A MIM:612265|HGNC:HGNC:13247|Ensembl:ENSG00000048828|Vega:OTTHUMG00000020252 +23197 FAF2 MIM:616935|HGNC:HGNC:24666|Ensembl:ENSG00000113194|Vega:OTTHUMG00000163228 +23198 PSME4 MIM:607705|HGNC:HGNC:20635|Ensembl:ENSG00000068878|Vega:OTTHUMG00000151852 +23199 GSE1 MIM:616886|HGNC:HGNC:28979|Ensembl:ENSG00000131149|Vega:OTTHUMG00000137650 +23200 ATP11B MIM:605869|HGNC:HGNC:13553|Ensembl:ENSG00000058063|Vega:OTTHUMG00000158295 +23201 FAM168A MIM:616316|HGNC:HGNC:28999|Ensembl:ENSG00000054965|Vega:OTTHUMG00000167995 +23203 PMPCA MIM:613036|HGNC:HGNC:18667|Ensembl:ENSG00000165688|Vega:OTTHUMG00000020926 +23204 ARL6IP1 MIM:607669|HGNC:HGNC:697|Ensembl:ENSG00000170540|Vega:OTTHUMG00000131367 +23205 ACSBG1 MIM:614362|HGNC:HGNC:29567|Ensembl:ENSG00000103740|Vega:OTTHUMG00000143734 +23207 PLEKHM2 MIM:609613|HGNC:HGNC:29131|Ensembl:ENSG00000116786|Vega:OTTHUMG00000003062 +23208 SYT11 MIM:608741|HGNC:HGNC:19239|Ensembl:ENSG00000132718|Vega:OTTHUMG00000014105 +23209 MLC1 MIM:605908|HGNC:HGNC:17082|Ensembl:ENSG00000100427|Vega:OTTHUMG00000150236 +23210 JMJD6 MIM:604914|HGNC:HGNC:19355|Ensembl:ENSG00000070495|Vega:OTTHUMG00000169267 +23211 ZC3H4 HGNC:HGNC:17808|Ensembl:ENSG00000130749|Vega:OTTHUMG00000183442 +23212 RRS1 HGNC:HGNC:17083|Ensembl:ENSG00000179041|Vega:OTTHUMG00000164765 +23213 SULF1 MIM:610012|HGNC:HGNC:20391|Ensembl:ENSG00000137573|Vega:OTTHUMG00000164466 +23214 XPO6 MIM:608411|HGNC:HGNC:19733|Ensembl:ENSG00000169180|Vega:OTTHUMG00000176782 +23215 PRRC2C MIM:617373|HGNC:HGNC:24903|Ensembl:ENSG00000117523|Vega:OTTHUMG00000034665 +23216 TBC1D1 MIM:609850|HGNC:HGNC:11578|Ensembl:ENSG00000065882|Vega:OTTHUMG00000150302 +23217 ZFR2 HGNC:HGNC:29189|Ensembl:ENSG00000105278|Vega:OTTHUMG00000180918 +23218 NBEAL2 MIM:614169|HGNC:HGNC:31928|Ensembl:ENSG00000160796|Vega:OTTHUMG00000156497 +23219 FBXO28 MIM:609100|HGNC:HGNC:29046|Ensembl:ENSG00000143756|Vega:OTTHUMG00000037495 +23220 DTX4 MIM:616110|HGNC:HGNC:29151|Ensembl:ENSG00000110042|Vega:OTTHUMG00000167336 +23221 RHOBTB2 MIM:607352|HGNC:HGNC:18756|Ensembl:ENSG00000008853|Vega:OTTHUMG00000097827 +23223 RRP12 HGNC:HGNC:29100|Ensembl:ENSG00000052749|Vega:OTTHUMG00000018855 +23224 SYNE2 MIM:608442|HGNC:HGNC:17084|Ensembl:ENSG00000054654|Vega:OTTHUMG00000140349 +23225 NUP210 MIM:607703|HGNC:HGNC:30052|Ensembl:ENSG00000132182|Vega:OTTHUMG00000157268 +23228 PLCL2 MIM:614276|HGNC:HGNC:9064|Ensembl:ENSG00000154822|Vega:OTTHUMG00000155467 +23229 ARHGEF9 MIM:300429|HGNC:HGNC:14561|Ensembl:ENSG00000131089|Vega:OTTHUMG00000021700 +23230 VPS13A MIM:605978|HGNC:HGNC:1908|Ensembl:ENSG00000197969|Vega:OTTHUMG00000020055 +23231 SEL1L3 HGNC:HGNC:29108|Ensembl:ENSG00000091490|Vega:OTTHUMG00000160331 +23232 TBC1D12 HGNC:HGNC:29082|Ensembl:ENSG00000108239|Vega:OTTHUMG00000018794 +23233 EXOC6B MIM:607880|HGNC:HGNC:17085|Ensembl:ENSG00000144036|Vega:OTTHUMG00000152723 +23234 DNAJC9 MIM:611206|HGNC:HGNC:19123|Ensembl:ENSG00000213551|Vega:OTTHUMG00000018461 +23235 SIK2 MIM:608973|HGNC:HGNC:21680|Ensembl:ENSG00000170145|Vega:OTTHUMG00000150644 +23236 PLCB1 MIM:607120|HGNC:HGNC:15917|Ensembl:ENSG00000182621|Vega:OTTHUMG00000031849 +23237 ARC MIM:612461|HGNC:HGNC:648|Ensembl:ENSG00000198576|Vega:OTTHUMG00000134310 +23239 PHLPP1 MIM:609396|HGNC:HGNC:20610|Ensembl:ENSG00000081913|Vega:OTTHUMG00000150629 +23240 TMEM131L MIM:616243|HGNC:HGNC:29146|Ensembl:ENSG00000121210|Vega:OTTHUMG00000153244 +23241 PACS2 MIM:610423|HGNC:HGNC:23794|Ensembl:ENSG00000179364|Vega:OTTHUMG00000170450 +23242 COBL MIM:610317|HGNC:HGNC:22199|Ensembl:ENSG00000106078|Vega:OTTHUMG00000155999 +23243 ANKRD28 MIM:611122|HGNC:HGNC:29024|Ensembl:ENSG00000206560|Vega:OTTHUMG00000155379 +23244 PDS5A MIM:613200|HGNC:HGNC:29088|Ensembl:ENSG00000121892|Vega:OTTHUMG00000160582 +23245 ASTN2 MIM:612856|HGNC:HGNC:17021|Ensembl:ENSG00000148219|Vega:OTTHUMG00000021013 +23246 BOP1 MIM:610596|HGNC:HGNC:15519|Ensembl:ENSG00000261236|Vega:OTTHUMG00000174603 +23247 KIAA0556 MIM:616650|HGNC:HGNC:29068|Ensembl:ENSG00000047578|Vega:OTTHUMG00000176780 +23248 RPRD2 MIM:614695|HGNC:HGNC:29039|Ensembl:ENSG00000163125|Vega:OTTHUMG00000012808 +23250 ATP11A MIM:605868|HGNC:HGNC:13552|Ensembl:ENSG00000068650|Vega:OTTHUMG00000017371 +23251 KIAA1024 HGNC:HGNC:29172|Ensembl:ENSG00000169330|Vega:OTTHUMG00000172073 +23252 OTUD3 MIM:611758|HGNC:HGNC:29038|Ensembl:ENSG00000169914|Vega:OTTHUMG00000002696 +23253 ANKRD12 MIM:610616|HGNC:HGNC:29135|Ensembl:ENSG00000101745|Vega:OTTHUMG00000131595 +23254 KAZN HGNC:HGNC:29173|Ensembl:ENSG00000189337|Vega:OTTHUMG00000002042 +23255 MTCL1 MIM:615766|HGNC:HGNC:29121|Ensembl:ENSG00000168502|Vega:OTTHUMG00000131594 +23256 SCFD1 HGNC:HGNC:20726|Ensembl:ENSG00000092108|Vega:OTTHUMG00000029420 +23258 DENND5A MIM:617278|HGNC:HGNC:19344|Ensembl:ENSG00000184014|Vega:OTTHUMG00000165716 +23259 DDHD2 MIM:615003|HGNC:HGNC:29106|Ensembl:ENSG00000085788|Vega:OTTHUMG00000164095 +23261 CAMTA1 MIM:611501|HGNC:HGNC:18806|Ensembl:ENSG00000171735|Vega:OTTHUMG00000001212 +23262 PPIP5K2 MIM:611648|HGNC:HGNC:29035|Ensembl:ENSG00000145725|Vega:OTTHUMG00000181461 +23263 MCF2L MIM:609499|HGNC:HGNC:14576|Ensembl:ENSG00000126217|Vega:OTTHUMG00000017377 +23264 ZC3H7B HGNC:HGNC:30869|Ensembl:ENSG00000100403|Vega:OTTHUMG00000150969 +23265 EXOC7 MIM:608163|HGNC:HGNC:23214|Ensembl:ENSG00000182473|Vega:OTTHUMG00000150720 +23266 ADGRL2 MIM:607018|HGNC:HGNC:18582|Ensembl:ENSG00000117114|Vega:OTTHUMG00000009844 +23268 DNMBP MIM:611282|HGNC:HGNC:30373|Ensembl:ENSG00000107554|Vega:OTTHUMG00000018897 +23269 MGA MIM:616061|HGNC:HGNC:14010|Ensembl:ENSG00000174197|Vega:OTTHUMG00000172719 +23270 TSPYL4 HGNC:HGNC:21559|Ensembl:ENSG00000187189|Vega:OTTHUMG00000015429 +23271 CAMSAP2 MIM:613775|HGNC:HGNC:29188|Ensembl:ENSG00000118200|Vega:OTTHUMG00000035740 +23272 FAM208A MIM:616493|HGNC:HGNC:30314|Ensembl:ENSG00000163946|Vega:OTTHUMG00000158827 +23274 CLEC16A MIM:611303|HGNC:HGNC:29013|Ensembl:ENSG00000038532|Vega:OTTHUMG00000152915 +23275 POFUT2 MIM:610249|HGNC:HGNC:14683|Ensembl:ENSG00000186866|Vega:OTTHUMG00000084874 +23276 KLHL18 HGNC:HGNC:29120|Ensembl:ENSG00000114648|Vega:OTTHUMG00000156522 +23277 CLUH MIM:616184|HGNC:HGNC:29094|Ensembl:ENSG00000132361|Vega:OTTHUMG00000177575 +23279 NUP160 MIM:607614|HGNC:HGNC:18017|Ensembl:ENSG00000030066|Vega:OTTHUMG00000166534 +23281 MTUS2 HGNC:HGNC:20595|Ensembl:ENSG00000132938|Vega:OTTHUMG00000016657 +23283 CSTF2T MIM:611968|HGNC:HGNC:17086|Ensembl:ENSG00000177613|Vega:OTTHUMG00000018246 +23284 ADGRL3 MIM:616417|HGNC:HGNC:20974|Ensembl:ENSG00000150471|Vega:OTTHUMG00000160690 +23285 KIAA1107 HGNC:HGNC:29192|Ensembl:ENSG00000069712|Vega:OTTHUMG00000010289 +23286 WWC1 MIM:610533|HGNC:HGNC:29435|Ensembl:ENSG00000113645|Vega:OTTHUMG00000130408 +23287 AGTPBP1 MIM:606830|HGNC:HGNC:17258|Ensembl:ENSG00000135049|Vega:OTTHUMG00000020124 +23288 IQCE HGNC:HGNC:29171|Ensembl:ENSG00000106012|Vega:OTTHUMG00000152047 +23291 FBXW11 MIM:605651|HGNC:HGNC:13607|Ensembl:ENSG00000072803|Vega:OTTHUMG00000163267 +23293 SMG6 MIM:610963|HGNC:HGNC:17809|Ensembl:ENSG00000070366|Vega:OTTHUMG00000177578 +23294 ANKS1A MIM:608994|HGNC:HGNC:20961|Ensembl:ENSG00000064999|Vega:OTTHUMG00000014559 +23295 MGRN1 MIM:607559|HGNC:HGNC:20254|Ensembl:ENSG00000102858|Vega:OTTHUMG00000176436 +23299 BICD2 MIM:609797|HGNC:HGNC:17208|Ensembl:ENSG00000185963|Vega:OTTHUMG00000021036 +23300 ATMIN MIM:614693|HGNC:HGNC:29034|Ensembl:ENSG00000166454|Vega:OTTHUMG00000176469 +23301 EHBP1 MIM:609922|HGNC:HGNC:29144|Ensembl:ENSG00000115504|Vega:OTTHUMG00000129453 +23302 WSCD1 HGNC:HGNC:29060|Ensembl:ENSG00000179314|Vega:OTTHUMG00000177794 +23303 KIF13B MIM:607350|HGNC:HGNC:14405|Ensembl:ENSG00000197892|Vega:OTTHUMG00000164032 +23304 UBR2 MIM:609134|HGNC:HGNC:21289|Ensembl:ENSG00000024048|Vega:OTTHUMG00000014703 +23305 ACSL6 MIM:604443|HGNC:HGNC:16496|Ensembl:ENSG00000164398|Ensembl:ENSG00000281938|Vega:OTTHUMG00000150692|Vega:OTTHUMG00000191412 +23306 NEMP1 MIM:616496|HGNC:HGNC:29001|Ensembl:ENSG00000166881|Vega:OTTHUMG00000171021 +23307 FKBP15 MIM:617398|HGNC:HGNC:23397|Ensembl:ENSG00000119321|Vega:OTTHUMG00000020518 +23308 ICOSLG MIM:605717|HGNC:HGNC:17087|Ensembl:ENSG00000160223|Vega:OTTHUMG00000086920 +23309 SIN3B MIM:607777|HGNC:HGNC:19354|Ensembl:ENSG00000127511|Vega:OTTHUMG00000182642 +23310 NCAPD3 MIM:609276|HGNC:HGNC:28952|Ensembl:ENSG00000151503|Vega:OTTHUMG00000167172 +23312 DMXL2 MIM:612186|HGNC:HGNC:2938|Ensembl:ENSG00000104093|Vega:OTTHUMG00000131749 +23313 KIAA0930 HGNC:HGNC:1314|Ensembl:ENSG00000100364|Vega:OTTHUMG00000151263 +23314 SATB2 MIM:608148|HGNC:HGNC:21637|Ensembl:ENSG00000119042|Vega:OTTHUMG00000132767 +23315 SLC9A8 MIM:612730|HGNC:HGNC:20728|Ensembl:ENSG00000197818|Vega:OTTHUMG00000032710 +23316 CUX2 MIM:610648|HGNC:HGNC:19347|Ensembl:ENSG00000111249|Vega:OTTHUMG00000169546 +23317 DNAJC13 MIM:614334|HGNC:HGNC:30343|Ensembl:ENSG00000138246|Vega:OTTHUMG00000159674 +23318 ZCCHC11 MIM:613692|HGNC:HGNC:28981|Ensembl:ENSG00000134744|Vega:OTTHUMG00000008200 +23321 TRIM2 MIM:614141|HGNC:HGNC:15974|Ensembl:ENSG00000109654|Vega:OTTHUMG00000155991 +23322 RPGRIP1L MIM:610937|HGNC:HGNC:29168|Ensembl:ENSG00000103494|Vega:OTTHUMG00000173125 +23324 MAN2B2 HGNC:HGNC:29623|Ensembl:ENSG00000013288|Vega:OTTHUMG00000160073 +23325 WASHC4 MIM:615748|HGNC:HGNC:29174|Ensembl:ENSG00000136051|Vega:OTTHUMG00000169838 +23326 USP22 MIM:612116|HGNC:HGNC:12621|Ensembl:ENSG00000124422|Vega:OTTHUMG00000133621 +23327 NEDD4L MIM:606384|HGNC:HGNC:7728|Ensembl:ENSG00000049759|Vega:OTTHUMG00000179875 +23328 SASH1 MIM:607955|HGNC:HGNC:19182|Ensembl:ENSG00000111961|Vega:OTTHUMG00000015773 +23329 TBC1D30 MIM:615077|HGNC:HGNC:29164|Ensembl:ENSG00000111490|Vega:OTTHUMG00000168824 +23331 TTC28 MIM:615098|HGNC:HGNC:29179|Ensembl:ENSG00000100154|Vega:OTTHUMG00000151006 +23332 CLASP1 MIM:605852|HGNC:HGNC:17088|Ensembl:ENSG00000074054|Vega:OTTHUMG00000153331 +23333 DPY19L1 MIM:613892|HGNC:HGNC:22205|Ensembl:ENSG00000173852|Vega:OTTHUMG00000154888 +23334 SZT2 MIM:615463|HGNC:HGNC:29040|Ensembl:ENSG00000198198|Vega:OTTHUMG00000007423 +23335 WDR7 MIM:613473|HGNC:HGNC:13490|Ensembl:ENSG00000091157|Vega:OTTHUMG00000132721 +23336 SYNM MIM:606087|HGNC:HGNC:24466|Ensembl:ENSG00000182253|Vega:OTTHUMG00000171887 +23338 JADE2 MIM:610515|HGNC:HGNC:22984|Ensembl:ENSG00000043143|Vega:OTTHUMG00000129122 +23339 VPS39 MIM:612188|HGNC:HGNC:20593|Ensembl:ENSG00000166887|Vega:OTTHUMG00000130467 +23341 DNAJC16 HGNC:HGNC:29157|Ensembl:ENSG00000116138|Vega:OTTHUMG00000002358 +23344 ESYT1 MIM:616670|HGNC:HGNC:29534|Ensembl:ENSG00000139641|Vega:OTTHUMG00000170197 +23345 SYNE1 MIM:608441|HGNC:HGNC:17089|Ensembl:ENSG00000131018|Vega:OTTHUMG00000015841 +23347 SMCHD1 MIM:614982|HGNC:HGNC:29090|Ensembl:ENSG00000101596|Vega:OTTHUMG00000178235 +23348 DOCK9 MIM:607325|HGNC:HGNC:14132|Ensembl:ENSG00000088387|Vega:OTTHUMG00000017260 +23349 PHF24 HGNC:HGNC:29180|Ensembl:ENSG00000122733|Vega:OTTHUMG00000019844 +23350 U2SURP HGNC:HGNC:30855|Ensembl:ENSG00000163714|Vega:OTTHUMG00000159323 +23351 KHNYN HGNC:HGNC:20166|Ensembl:ENSG00000100441|Vega:OTTHUMG00000171312 +23352 UBR4 MIM:609890|HGNC:HGNC:30313|Ensembl:ENSG00000127481|Vega:OTTHUMG00000002498 +23353 SUN1 MIM:607723|HGNC:HGNC:18587|Ensembl:ENSG00000164828|Vega:OTTHUMG00000151426 +23354 HAUS5 MIM:613432|HGNC:HGNC:29130|Ensembl:ENSG00000249115|Vega:OTTHUMG00000048110 +23355 VPS8 HGNC:HGNC:29122|Ensembl:ENSG00000156931|Vega:OTTHUMG00000156707 +23357 ANGEL1 HGNC:HGNC:19961|Ensembl:ENSG00000013523|Vega:OTTHUMG00000171494 +23358 USP24 MIM:610569|HGNC:HGNC:12623|Ensembl:ENSG00000162402|Vega:OTTHUMG00000008135 +23359 FAM189A1 HGNC:HGNC:29075|Ensembl:ENSG00000104059|Vega:OTTHUMG00000172185 +23360 FNBP4 MIM:615265|HGNC:HGNC:19752|Ensembl:ENSG00000109920|Vega:OTTHUMG00000166533 +23361 ZNF629 HGNC:HGNC:29008|Ensembl:ENSG00000102870|Vega:OTTHUMG00000176905 +23362 PSD3 MIM:614440|HGNC:HGNC:19093|Ensembl:ENSG00000156011|Vega:OTTHUMG00000163711 +23363 OBSL1 MIM:610991|HGNC:HGNC:29092|Ensembl:ENSG00000124006|Vega:OTTHUMG00000059157 +23365 ARHGEF12 MIM:604763|HGNC:HGNC:14193|Ensembl:ENSG00000196914|Vega:OTTHUMG00000166143 +23366 KIAA0895 HGNC:HGNC:22206|Ensembl:ENSG00000164542|Vega:OTTHUMG00000154939 +23367 LARP1 MIM:612059|HGNC:HGNC:29531|Ensembl:ENSG00000155506|Vega:OTTHUMG00000130191 +23368 PPP1R13B MIM:606455|HGNC:HGNC:14950|Ensembl:ENSG00000088808|Vega:OTTHUMG00000171647 +23369 PUM2 MIM:607205|HGNC:HGNC:14958|Ensembl:ENSG00000055917|Vega:OTTHUMG00000122098 +23370 ARHGEF18 MIM:616432|HGNC:HGNC:17090|Ensembl:ENSG00000104880|Ensembl:ENSG00000268861|Vega:OTTHUMG00000177341|Vega:OTTHUMG00000177342 +23371 TNS2 MIM:607717|HGNC:HGNC:19737|Ensembl:ENSG00000111077|Vega:OTTHUMG00000169730 +23373 CRTC1 MIM:607536|HGNC:HGNC:16062|Ensembl:ENSG00000105662|Vega:OTTHUMG00000183115 +23376 UFL1 MIM:613372|HGNC:HGNC:23039|Ensembl:ENSG00000014123|Vega:OTTHUMG00000015238 +23378 RRP8 MIM:615818|HGNC:HGNC:29030|Ensembl:ENSG00000132275|Vega:OTTHUMG00000165503 +23379 ICE1 HGNC:HGNC:29154|Ensembl:ENSG00000164151|Vega:OTTHUMG00000161639 +23380 SRGAP2 MIM:606524|HGNC:HGNC:19751|Ensembl:ENSG00000266028|Vega:OTTHUMG00000184381 +23381 SMG5 MIM:610962|HGNC:HGNC:24644|Ensembl:ENSG00000198952|Vega:OTTHUMG00000017491 +23382 AHCYL2 MIM:616520|HGNC:HGNC:22204|Ensembl:ENSG00000158467|Vega:OTTHUMG00000157677 +23383 MAU2 MIM:614560|HGNC:HGNC:29140|Ensembl:ENSG00000129933|Vega:OTTHUMG00000150188 +23384 SPECC1L MIM:614140|HGNC:HGNC:29022|Ensembl:ENSG00000100014|Vega:OTTHUMG00000171450 +23385 NCSTN MIM:605254|HGNC:HGNC:17091|Ensembl:ENSG00000162736|Vega:OTTHUMG00000033110 +23386 NUDCD3 MIM:610296|HGNC:HGNC:22208|Ensembl:ENSG00000015676|Vega:OTTHUMG00000129174 +23387 SIK3 MIM:614776|HGNC:HGNC:29165|Ensembl:ENSG00000160584|Vega:OTTHUMG00000066628 +23389 MED13L MIM:608771|HGNC:HGNC:22962|Ensembl:ENSG00000123066|Vega:OTTHUMG00000169404 +23390 ZDHHC17 MIM:607799|HGNC:HGNC:18412|Ensembl:ENSG00000186908|Vega:OTTHUMG00000169917 +23392 KIAA0368 MIM:616694|HGNC:HGNC:29020|Ensembl:ENSG00000136813|Vega:OTTHUMG00000020489 +23394 ADNP MIM:611386|HGNC:HGNC:15766|Ensembl:ENSG00000101126|Vega:OTTHUMG00000032737 +23395 LARS2 MIM:604544|HGNC:HGNC:17095|Ensembl:ENSG00000011376|Vega:OTTHUMG00000133177 +23396 PIP5K1C MIM:606102|HGNC:HGNC:8996|Ensembl:ENSG00000186111|Vega:OTTHUMG00000180870 +23397 NCAPH MIM:602332|HGNC:HGNC:1112|Ensembl:ENSG00000121152|Vega:OTTHUMG00000130451 +23398 PPWD1 HGNC:HGNC:28954|Ensembl:ENSG00000113593|Vega:OTTHUMG00000131226 +23399 CTDNEP1 MIM:610684|HGNC:HGNC:19085|Ensembl:ENSG00000175826|Vega:OTTHUMG00000102180 +23400 ATP13A2 MIM:610513|HGNC:HGNC:30213|Ensembl:ENSG00000159363|Vega:OTTHUMG00000002293 +23401 FRAT2 MIM:605006|HGNC:HGNC:16048|Ensembl:ENSG00000181274|Vega:OTTHUMG00000018850 +23403 FBXO46 MIM:609117|HGNC:HGNC:25069|Ensembl:ENSG00000177051|Vega:OTTHUMG00000182132 +23404 EXOSC2 MIM:602238|HGNC:HGNC:17097|Ensembl:ENSG00000130713|Vega:OTTHUMG00000020811 +23405 DICER1 MIM:606241|HGNC:HGNC:17098|Ensembl:ENSG00000100697|Vega:OTTHUMG00000166134 +23406 COTL1 MIM:606748|HGNC:HGNC:18304|Ensembl:ENSG00000103187|Vega:OTTHUMG00000137634 +23408 SIRT5 MIM:604483|HGNC:HGNC:14933|Ensembl:ENSG00000124523|Vega:OTTHUMG00000014278 +23409 SIRT4 MIM:604482|HGNC:HGNC:14932|Ensembl:ENSG00000089163|Vega:OTTHUMG00000169028 +23410 SIRT3 MIM:604481|HGNC:HGNC:14931|Ensembl:ENSG00000142082|Vega:OTTHUMG00000119074 +23411 SIRT1 MIM:604479|HGNC:HGNC:14929|Ensembl:ENSG00000096717|Vega:OTTHUMG00000018340 +23412 COMMD3 MIM:616700|HGNC:HGNC:23332|Ensembl:ENSG00000148444|Vega:OTTHUMG00000017806 +23413 NCS1 MIM:603315|HGNC:HGNC:3953|Ensembl:ENSG00000107130|Vega:OTTHUMG00000020801 +23414 ZFPM2 MIM:603693|HGNC:HGNC:16700|Ensembl:ENSG00000169946|Vega:OTTHUMG00000164818 +23415 KCNH4 MIM:604528|HGNC:HGNC:6253|Ensembl:ENSG00000089558|Vega:OTTHUMG00000180106 +23416 KCNH3 MIM:604527|HGNC:HGNC:6252|Ensembl:ENSG00000135519|Vega:OTTHUMG00000169517 +23417 MLYCD MIM:606761|HGNC:HGNC:7150|Ensembl:ENSG00000103150|Vega:OTTHUMG00000176654 +23418 CRB1 MIM:604210|HGNC:HGNC:2343|Ensembl:ENSG00000134376|Vega:OTTHUMG00000035663 +23420 NOMO1 MIM:609157|HGNC:HGNC:30060|Ensembl:ENSG00000103512|Vega:OTTHUMG00000090541 +23421 ITGB3BP MIM:605494|HGNC:HGNC:6157|Ensembl:ENSG00000142856|Vega:OTTHUMG00000013364 +23423 TMED3 HGNC:HGNC:28889|Ensembl:ENSG00000166557|Vega:OTTHUMG00000144170 +23424 TDRD7 MIM:611258|HGNC:HGNC:30831|Ensembl:ENSG00000196116|Vega:OTTHUMG00000020326 +23426 GRIP1 MIM:604597|HGNC:HGNC:18708|Ensembl:ENSG00000155974|Vega:OTTHUMG00000169019 +23428 SLC7A8 MIM:604235|HGNC:HGNC:11066|Ensembl:ENSG00000092068|Vega:OTTHUMG00000028720 +23429 RYBP MIM:607535|HGNC:HGNC:10480|Ensembl:ENSG00000163602 +23430 TPSD1 MIM:609272|HGNC:HGNC:14118|Ensembl:ENSG00000095917|Vega:OTTHUMG00000128511 +23431 AP4E1 MIM:607244|HGNC:HGNC:573|Ensembl:ENSG00000081014|Vega:OTTHUMG00000172458 +23432 GPR161 MIM:612250|HGNC:HGNC:23694|Ensembl:ENSG00000143147|Vega:OTTHUMG00000034651 +23433 RHOQ MIM:605857|HGNC:HGNC:17736|Ensembl:ENSG00000119729|Vega:OTTHUMG00000150653 +23434 LINC01565 HGNC:HGNC:17099|Ensembl:ENSG00000198685 +23435 TARDBP MIM:605078|HGNC:HGNC:11571|Ensembl:ENSG00000120948|Vega:OTTHUMG00000002120 +23436 CELA3B HGNC:HGNC:15945|Ensembl:ENSG00000219073|Vega:OTTHUMG00000002758 +23437 TRS-AGA2-3 MIM:189910|HGNC:HGNC:16293 +23438 HARS2 MIM:600783|HGNC:HGNC:4817|Ensembl:ENSG00000112855|Vega:OTTHUMG00000129500 +23439 ATP1B4 HGNC:HGNC:808|Ensembl:ENSG00000101892|Vega:OTTHUMG00000022299 +23440 OTP MIM:604529|HGNC:HGNC:8518|Ensembl:ENSG00000171540|Vega:OTTHUMG00000102171 +23443 SLC35A3 MIM:605632|HGNC:HGNC:11023|Ensembl:ENSG00000117620|Ensembl:ENSG00000283761|Vega:OTTHUMG00000010805 +23446 SLC44A1 MIM:606105|HGNC:HGNC:18798|Ensembl:ENSG00000070214|Vega:OTTHUMG00000020421 +23450 SF3B3 MIM:605592|HGNC:HGNC:10770|Ensembl:ENSG00000189091|Vega:OTTHUMG00000137582 +23451 SF3B1 MIM:605590|HGNC:HGNC:10768|Ensembl:ENSG00000115524|Vega:OTTHUMG00000154447 +23452 ANGPTL2 MIM:605001|HGNC:HGNC:490|Ensembl:ENSG00000136859|Vega:OTTHUMG00000020695 +23456 ABCB10 MIM:605454|HGNC:HGNC:41|Ensembl:ENSG00000135776|Vega:OTTHUMG00000039471 +23457 ABCB9 MIM:605453|HGNC:HGNC:50|Ensembl:ENSG00000150967|Vega:OTTHUMG00000168769 +23459 CMD1H MIM:604288|HGNC:HGNC:2108 +23460 ABCA6 MIM:612504|HGNC:HGNC:36|Ensembl:ENSG00000154262|Vega:OTTHUMG00000180258 +23461 ABCA5 MIM:612503|HGNC:HGNC:35|Ensembl:ENSG00000154265|Vega:OTTHUMG00000180303 +23462 HEY1 MIM:602953|HGNC:HGNC:4880|Ensembl:ENSG00000164683|Vega:OTTHUMG00000164641 +23463 ICMT MIM:605851|HGNC:HGNC:5350|Ensembl:ENSG00000116237|Vega:OTTHUMG00000001254 +23464 GCAT MIM:607422|HGNC:HGNC:4188|Ensembl:ENSG00000100116|Vega:OTTHUMG00000150664 +23466 CBX6 MIM:617438|HGNC:HGNC:1556|Ensembl:ENSG00000183741|Vega:OTTHUMG00000150456 +23467 NPTXR MIM:609474|HGNC:HGNC:7954|Ensembl:ENSG00000221890|Vega:OTTHUMG00000150458 +23468 CBX5 MIM:604478|HGNC:HGNC:1555|Ensembl:ENSG00000094916|Vega:OTTHUMG00000169700 +23469 PHF3 MIM:607789|HGNC:HGNC:8921|Ensembl:ENSG00000118482|Vega:OTTHUMG00000014952 +23471 TRAM1 MIM:605190|HGNC:HGNC:20568|Ensembl:ENSG00000067167|Vega:OTTHUMG00000164428 +23473 CAPN7 MIM:606400|HGNC:HGNC:1484|Ensembl:ENSG00000131375|Vega:OTTHUMG00000129863 +23474 ETHE1 MIM:608451|HGNC:HGNC:23287|Ensembl:ENSG00000105755|Vega:OTTHUMG00000182697 +23475 QPRT MIM:606248|HGNC:HGNC:9755|Ensembl:ENSG00000103485|Vega:OTTHUMG00000097770 +23476 BRD4 MIM:608749|HGNC:HGNC:13575|Ensembl:ENSG00000141867|Vega:OTTHUMG00000183252 +23478 SEC11A HGNC:HGNC:17718|Ensembl:ENSG00000140612|Vega:OTTHUMG00000172489 +23479 ISCU MIM:611911|HGNC:HGNC:29882|Ensembl:ENSG00000136003|Vega:OTTHUMG00000168420 +23480 SEC61G MIM:609215|HGNC:HGNC:18277|Ensembl:ENSG00000132432|Vega:OTTHUMG00000023430 +23481 PES1 MIM:605819|HGNC:HGNC:8848|Ensembl:ENSG00000100029|Vega:OTTHUMG00000151077 +23483 TGDS MIM:616146|HGNC:HGNC:20324|Ensembl:ENSG00000088451|Vega:OTTHUMG00000046308 +23484 LEPROTL1 MIM:607338|HGNC:HGNC:6555|Ensembl:ENSG00000104660|Vega:OTTHUMG00000163820 +23491 CES3 MIM:605279|HGNC:HGNC:1865|Ensembl:ENSG00000172828|Vega:OTTHUMG00000137525 +23492 CBX7 MIM:608457|HGNC:HGNC:1557|Ensembl:ENSG00000100307|Vega:OTTHUMG00000150418 +23493 HEY2 MIM:604674|HGNC:HGNC:4881|Ensembl:ENSG00000135547|Vega:OTTHUMG00000015512 +23495 TNFRSF13B MIM:604907|HGNC:HGNC:18153|Ensembl:ENSG00000240505|Vega:OTTHUMG00000059262 +23498 HAAO MIM:604521|HGNC:HGNC:4796|Ensembl:ENSG00000162882|Vega:OTTHUMG00000152348 +23499 MACF1 MIM:608271|HGNC:HGNC:13664|Ensembl:ENSG00000127603|Vega:OTTHUMG00000007754 +23500 DAAM2 MIM:606627|HGNC:HGNC:18143|Ensembl:ENSG00000146122|Vega:OTTHUMG00000014653 +23503 ZFYVE26 MIM:612012|HGNC:HGNC:20761|Ensembl:ENSG00000072121|Vega:OTTHUMG00000171274 +23504 RIMBP2 MIM:611602|HGNC:HGNC:30339|Ensembl:ENSG00000060709|Vega:OTTHUMG00000168385 +23505 TMEM131 MIM:615659|HGNC:HGNC:30366|Ensembl:ENSG00000075568|Vega:OTTHUMG00000153061 +23506 BICRAL HGNC:HGNC:21111|Ensembl:ENSG00000112624|Vega:OTTHUMG00000014706 +23507 LRRC8B MIM:612888|HGNC:HGNC:30692|Ensembl:ENSG00000197147|Vega:OTTHUMG00000010129 +23508 TTC9 MIM:610488|HGNC:HGNC:20267|Ensembl:ENSG00000133985|Vega:OTTHUMG00000172133 +23509 POFUT1 MIM:607491|HGNC:HGNC:14988|Ensembl:ENSG00000101346|Vega:OTTHUMG00000133268 +23510 KCTD2 MIM:613422|HGNC:HGNC:21294|Ensembl:ENSG00000180901|Vega:OTTHUMG00000179276 +23511 NUP188 MIM:615587|HGNC:HGNC:17859|Ensembl:ENSG00000095319|Vega:OTTHUMG00000020768 +23512 SUZ12 MIM:606245|HGNC:HGNC:17101|Ensembl:ENSG00000178691|Vega:OTTHUMG00000132813 +23513 SCRIB MIM:607733|HGNC:HGNC:30377|Ensembl:ENSG00000180900|Vega:OTTHUMG00000165154 +23514 SPIDR MIM:615384|HGNC:HGNC:28971|Ensembl:ENSG00000164808|Vega:OTTHUMG00000164176 +23515 MORC3 MIM:610078|HGNC:HGNC:23572|Ensembl:ENSG00000159256|Vega:OTTHUMG00000086620 +23516 SLC39A14 MIM:608736|HGNC:HGNC:20858|Ensembl:ENSG00000104635|Vega:OTTHUMG00000097791 +23517 SKIV2L2 HGNC:HGNC:18734|Ensembl:ENSG00000039123|Vega:OTTHUMG00000097019 +23518 R3HDM1 HGNC:HGNC:9757|Ensembl:ENSG00000048991|Vega:OTTHUMG00000131740 +23519 ANP32D MIM:606878|HGNC:HGNC:16676|Ensembl:ENSG00000139223|Vega:OTTHUMG00000162681 +23520 ANP32C MIM:606877|HGNC:HGNC:16675 +23521 RPL13A HGNC:HGNC:10304|Ensembl:ENSG00000142541|Vega:OTTHUMG00000134289 +23522 KAT6B MIM:605880|HGNC:HGNC:17582|Ensembl:ENSG00000156650|Vega:OTTHUMG00000018509 +23523 CABIN1 MIM:604251|HGNC:HGNC:24187|Ensembl:ENSG00000099991|Vega:OTTHUMG00000150797 +23524 SRRM2 MIM:606032|HGNC:HGNC:16639|Ensembl:ENSG00000167978|Vega:OTTHUMG00000177358 +23526 ARHGAP45 MIM:601155|HGNC:HGNC:17102|Ensembl:ENSG00000180448|Vega:OTTHUMG00000181871 +23527 ACAP2 MIM:607766|HGNC:HGNC:16469|Ensembl:ENSG00000114331|Vega:OTTHUMG00000155885 +23528 ZNF281 HGNC:HGNC:13075|Ensembl:ENSG00000162702|Vega:OTTHUMG00000035724 +23529 CLCF1 MIM:607672|HGNC:HGNC:17412|Ensembl:ENSG00000175505|Vega:OTTHUMG00000167669 +23530 NNT MIM:607878|HGNC:HGNC:7863|Ensembl:ENSG00000112992|Vega:OTTHUMG00000096961 +23531 MMD MIM:604467|HGNC:HGNC:7153|Ensembl:ENSG00000108960|Vega:OTTHUMG00000177845 +23532 PRAME MIM:606021|HGNC:HGNC:9336|Ensembl:ENSG00000185686|Vega:OTTHUMG00000151172 +23533 PIK3R5 MIM:611317|HGNC:HGNC:30035|Ensembl:ENSG00000141506|Vega:OTTHUMG00000108197 +23534 TNPO3 MIM:610032|HGNC:HGNC:17103|Ensembl:ENSG00000064419|Vega:OTTHUMG00000158409 +23536 ADAT1 MIM:604230|HGNC:HGNC:228|Ensembl:ENSG00000065457|Vega:OTTHUMG00000137611 +23538 OR52A1 HGNC:HGNC:8318|Ensembl:ENSG00000182070|Vega:OTTHUMG00000066603 +23539 SLC16A8 MIM:610409|HGNC:HGNC:16270|Ensembl:ENSG00000100156|Vega:OTTHUMG00000151196 +23540 TRS-TGA4-1 MIM:606172|HGNC:HGNC:16294 +23541 SEC14L2 MIM:607558|HGNC:HGNC:10699|Ensembl:ENSG00000100003|Vega:OTTHUMG00000151024 +23542 MAPK8IP2 MIM:607755|HGNC:HGNC:6883|Ensembl:ENSG00000008735|Vega:OTTHUMG00000150181 +23543 RBFOX2 MIM:612149|HGNC:HGNC:9906|Ensembl:ENSG00000100320|Vega:OTTHUMG00000150585 +23544 SEZ6L MIM:607021|HGNC:HGNC:10763|Ensembl:ENSG00000100095|Vega:OTTHUMG00000150870 +23545 ATP6V0A2 MIM:611716|HGNC:HGNC:18481|Ensembl:ENSG00000185344|Vega:OTTHUMG00000168723 +23546 SYNGR4 MIM:608373|HGNC:HGNC:11502|Ensembl:ENSG00000105467|Vega:OTTHUMG00000183214 +23547 LILRA4 MIM:607517|HGNC:HGNC:15503|Ensembl:ENSG00000239961|Vega:OTTHUMG00000065355 +23548 TTC33 HGNC:HGNC:29959|Ensembl:ENSG00000113638|Vega:OTTHUMG00000131142 +23549 DNPEP MIM:611367|HGNC:HGNC:2981|Ensembl:ENSG00000123992|Vega:OTTHUMG00000058919 +23550 PSD4 MIM:614442|HGNC:HGNC:19096|Ensembl:ENSG00000125637|Vega:OTTHUMG00000153339 +23551 RASD2 MIM:612842|HGNC:HGNC:18229|Ensembl:ENSG00000100302|Vega:OTTHUMG00000150607 +23552 CDK20 MIM:610076|HGNC:HGNC:21420|Ensembl:ENSG00000156345|Vega:OTTHUMG00000020161 +23553 HYAL4 MIM:604510|HGNC:HGNC:5323|Ensembl:ENSG00000106302|Vega:OTTHUMG00000157349 +23554 TSPAN12 MIM:613138|HGNC:HGNC:21641|Ensembl:ENSG00000106025|Vega:OTTHUMG00000156980 +23555 TSPAN15 MIM:613140|HGNC:HGNC:23298|Ensembl:ENSG00000099282|Vega:OTTHUMG00000018381 +23556 PIGN MIM:606097|HGNC:HGNC:8967|Ensembl:ENSG00000197563|Vega:OTTHUMG00000180098 +23557 SNAPIN MIM:607007|HGNC:HGNC:17145|Ensembl:ENSG00000143553|Vega:OTTHUMG00000037086 +23558 WBP2 MIM:606962|HGNC:HGNC:12738|Ensembl:ENSG00000132471|Vega:OTTHUMG00000179896 +23559 WBP1 MIM:606961|HGNC:HGNC:12737|Ensembl:ENSG00000239779|Vega:OTTHUMG00000129958 +23560 GTPBP4 HGNC:HGNC:21535|Ensembl:ENSG00000107937|Vega:OTTHUMG00000017538 +23562 CLDN14 MIM:605608|HGNC:HGNC:2035|Ensembl:ENSG00000159261|Vega:OTTHUMG00000086638 +23563 CHST5 MIM:604817|HGNC:HGNC:1973|Ensembl:ENSG00000135702|Vega:OTTHUMG00000137610 +23564 DDAH2 MIM:604744|HGNC:HGNC:2716|Ensembl:ENSG00000213722|Vega:OTTHUMG00000031212 +23566 LPAR3 MIM:605106|HGNC:HGNC:14298|Ensembl:ENSG00000171517|Vega:OTTHUMG00000009925 +23567 ZNF346 MIM:605308|HGNC:HGNC:16403|Ensembl:ENSG00000113761|Vega:OTTHUMG00000130848 +23568 ARL2BP MIM:615407|HGNC:HGNC:17146|Ensembl:ENSG00000102931|Vega:OTTHUMG00000133459 +23569 PADI4 MIM:605347|HGNC:HGNC:18368|Ensembl:ENSG00000159339|Vega:OTTHUMG00000002371 +23574 PRG1 MIM:605157 +23576 DDAH1 MIM:604743|HGNC:HGNC:2715|Ensembl:ENSG00000153904|Vega:OTTHUMG00000191181 +23580 CDC42EP4 MIM:605468|HGNC:HGNC:17147|Ensembl:ENSG00000179604|Vega:OTTHUMG00000178419 +23581 CASP14 MIM:605848|HGNC:HGNC:1502|Ensembl:ENSG00000105141|Vega:OTTHUMG00000183205 +23582 CCNDBP1 MIM:607089|HGNC:HGNC:1587|Ensembl:ENSG00000166946|Vega:OTTHUMG00000130703 +23583 SMUG1 MIM:607753|HGNC:HGNC:17148|Ensembl:ENSG00000123415|Vega:OTTHUMG00000160068 +23584 VSIG2 MIM:606011|HGNC:HGNC:17149|Ensembl:ENSG00000019102|Vega:OTTHUMG00000150357 +23585 TMEM50A MIM:605348|HGNC:HGNC:30590|Ensembl:ENSG00000183726|Vega:OTTHUMG00000007651 +23586 DDX58 MIM:609631|HGNC:HGNC:19102|Ensembl:ENSG00000107201|Vega:OTTHUMG00000019746 +23587 ELP5 MIM:615019|HGNC:HGNC:30617|Ensembl:ENSG00000170291|Vega:OTTHUMG00000177974 +23588 KLHDC2 MIM:611280|HGNC:HGNC:20231|Ensembl:ENSG00000165516|Vega:OTTHUMG00000140288 +23589 CARHSP1 MIM:616885|HGNC:HGNC:17150|Ensembl:ENSG00000153048|Vega:OTTHUMG00000129695 +23590 PDSS1 MIM:607429|HGNC:HGNC:17759|Ensembl:ENSG00000148459|Vega:OTTHUMG00000017844 +23591 FAM215A HGNC:HGNC:17505|Ensembl:ENSG00000267496 +23592 LEMD3 MIM:607844|HGNC:HGNC:28887|Ensembl:ENSG00000174106|Vega:OTTHUMG00000168840 +23593 HEBP2 MIM:605825|HGNC:HGNC:15716|Ensembl:ENSG00000051620|Vega:OTTHUMG00000015671 +23594 ORC6 MIM:607213|HGNC:HGNC:17151|Ensembl:ENSG00000091651|Vega:OTTHUMG00000132539 +23595 ORC3 MIM:604972|HGNC:HGNC:8489|Ensembl:ENSG00000135336|Vega:OTTHUMG00000015179 +23596 OPN3 MIM:606695|HGNC:HGNC:14007|Ensembl:ENSG00000054277|Vega:OTTHUMG00000039691 +23597 ACOT9 MIM:300862|HGNC:HGNC:17152|Ensembl:ENSG00000123130|Vega:OTTHUMG00000021257 +23598 PATZ1 MIM:605165|HGNC:HGNC:13071|Ensembl:ENSG00000100105|Vega:OTTHUMG00000151254 +23600 AMACR MIM:604489|HGNC:HGNC:451|Ensembl:ENSG00000242110|Vega:OTTHUMG00000090734 +23601 CLEC5A MIM:604987|HGNC:HGNC:2054|Ensembl:ENSG00000258227|Vega:OTTHUMG00000157173 +23603 CORO1C MIM:605269|HGNC:HGNC:2254|Ensembl:ENSG00000110880|Vega:OTTHUMG00000169381 +23604 DAPK2 MIM:616567|HGNC:HGNC:2675|Ensembl:ENSG00000035664|Vega:OTTHUMG00000132947 +23605 HMGN2P9 HGNC:HGNC:4987 +23606 HMGN2P10 HGNC:HGNC:4988 +23607 CD2AP MIM:604241|HGNC:HGNC:14258|Ensembl:ENSG00000198087|Vega:OTTHUMG00000014799 +23608 MKRN1 MIM:607754|HGNC:HGNC:7112|Ensembl:ENSG00000133606|Vega:OTTHUMG00000157412 +23609 MKRN2 MIM:608426|HGNC:HGNC:7113|Ensembl:ENSG00000075975|Vega:OTTHUMG00000155371 +23610 MKRN6P HGNC:HGNC:7118 +23612 PHLDA3 MIM:607054|HGNC:HGNC:8934|Ensembl:ENSG00000174307|Vega:OTTHUMG00000035767 +23613 ZMYND8 MIM:615713|HGNC:HGNC:9397|Ensembl:ENSG00000101040|Vega:OTTHUMG00000032667 +23614 PPY2P MIM:606638|HGNC:HGNC:9328|Ensembl:ENSG00000265060 +23615 PYY2 MIM:606637|HGNC:HGNC:9749|Ensembl:ENSG00000237575 +23616 SH3BP1 MIM:617368|HGNC:HGNC:10824|Ensembl:ENSG00000100092|Vega:OTTHUMG00000030996 +23617 TSSK2 MIM:610710|HGNC:HGNC:11401|Ensembl:ENSG00000206203|Vega:OTTHUMG00000150118 +23619 ZIM2 HGNC:HGNC:12875|Ensembl:ENSG00000269699|Vega:OTTHUMG00000171953 +23620 NTSR2 MIM:605538|HGNC:HGNC:8040|Ensembl:ENSG00000169006|Vega:OTTHUMG00000119083 +23621 BACE1 MIM:604252|HGNC:HGNC:933|Ensembl:ENSG00000186318|Vega:OTTHUMG00000160636 +23623 RUSC1 MIM:617318|HGNC:HGNC:17153|Ensembl:ENSG00000160753|Vega:OTTHUMG00000013910 +23624 CBLC MIM:608453|HGNC:HGNC:15961|Ensembl:ENSG00000142273|Vega:OTTHUMG00000150715 +23625 FAM89B MIM:616128|HGNC:HGNC:16708|Ensembl:ENSG00000176973|Vega:OTTHUMG00000166499 +23626 SPO11 MIM:605114|HGNC:HGNC:11250|Ensembl:ENSG00000054796|Vega:OTTHUMG00000032817 +23627 PRND MIM:604263|HGNC:HGNC:15748|Ensembl:ENSG00000171864|Vega:OTTHUMG00000031789 +23629 BRD7P3 HGNC:HGNC:24171 +23630 KCNE5 MIM:300328|HGNC:HGNC:6241|Ensembl:ENSG00000176076|Vega:OTTHUMG00000022189 +23632 CA14 MIM:604832|HGNC:HGNC:1372|Ensembl:ENSG00000118298|Vega:OTTHUMG00000012549 +23633 KPNA6 MIM:610563|HGNC:HGNC:6399|Ensembl:ENSG00000025800|Vega:OTTHUMG00000004333 +23635 SSBP2 MIM:607389|HGNC:HGNC:15831|Ensembl:ENSG00000145687|Vega:OTTHUMG00000119039 +23636 NUP62 MIM:605815|HGNC:HGNC:8066|Ensembl:ENSG00000213024|Vega:OTTHUMG00000183077 +23637 RABGAP1 MIM:615882|HGNC:HGNC:17155|Ensembl:ENSG00000011454|Vega:OTTHUMG00000020633 +23639 LRRC6 MIM:614930|HGNC:HGNC:16725|Ensembl:ENSG00000129295|Vega:OTTHUMG00000164646 +23640 HSPBP1 MIM:612939|HGNC:HGNC:24989|Ensembl:ENSG00000133265|Vega:OTTHUMG00000180705 +23641 LDOC1 MIM:300402|HGNC:HGNC:6548|Ensembl:ENSG00000182195|Vega:OTTHUMG00000022558 +23642 SNHG1 MIM:603222|HGNC:HGNC:32688|Ensembl:ENSG00000255717 +23643 LY96 MIM:605243|HGNC:HGNC:17156|Ensembl:ENSG00000154589|Vega:OTTHUMG00000164504 +23644 EDC4 MIM:606030|HGNC:HGNC:17157|Ensembl:ENSG00000038358|Vega:OTTHUMG00000137543 +23645 PPP1R15A MIM:611048|HGNC:HGNC:14375|Ensembl:ENSG00000087074|Vega:OTTHUMG00000183330 +23646 PLD3 MIM:615698|HGNC:HGNC:17158|Ensembl:ENSG00000105223|Vega:OTTHUMG00000152736 +23647 ARFIP2 MIM:601638|HGNC:HGNC:17160|Ensembl:ENSG00000132254|Vega:OTTHUMG00000133406 +23648 SSBP3 MIM:607390|HGNC:HGNC:15674|Ensembl:ENSG00000157216|Vega:OTTHUMG00000008264 +23649 POLA2 HGNC:HGNC:30073|Ensembl:ENSG00000014138|Vega:OTTHUMG00000165951 +23650 TRIM29 MIM:610658|HGNC:HGNC:17274|Ensembl:ENSG00000137699|Vega:OTTHUMG00000140377 +23654 PLXNB2 MIM:604293|HGNC:HGNC:9104|Ensembl:ENSG00000196576|Vega:OTTHUMG00000150219 +23657 SLC7A11 MIM:607933|HGNC:HGNC:11059|Ensembl:ENSG00000151012|Vega:OTTHUMG00000133396 +23658 LSM5 MIM:607285|HGNC:HGNC:17162|Ensembl:ENSG00000106355|Vega:OTTHUMG00000022913 +23659 PLA2G15 MIM:609362|HGNC:HGNC:17163|Ensembl:ENSG00000103066|Vega:OTTHUMG00000137554 +23660 ZKSCAN5 MIM:611272|HGNC:HGNC:12867|Ensembl:ENSG00000196652|Vega:OTTHUMG00000156749 +23662 USH3B HGNC:HGNC:12606 +23666 UBBP4 HGNC:HGNC:12467 +23667 UBBP3 HGNC:HGNC:12466 +23668 UBBP2 HGNC:HGNC:12465 +23670 TMEM2 MIM:605835|HGNC:HGNC:11869|Ensembl:ENSG00000135048|Vega:OTTHUMG00000020000 +23671 TMEFF2 MIM:605734|HGNC:HGNC:11867|Ensembl:ENSG00000144339|Vega:OTTHUMG00000132723 +23673 STX12 MIM:606892|HGNC:HGNC:11430|Ensembl:ENSG00000117758|Vega:OTTHUMG00000003730 +23676 SMPX MIM:300066|MIM:300226|HGNC:HGNC:11122|Ensembl:ENSG00000091482|Vega:OTTHUMG00000021235 +23677 SH3BP4 MIM:605611|HGNC:HGNC:10826|Ensembl:ENSG00000130147|Vega:OTTHUMG00000133292 +23678 SGK3 MIM:607591|HGNC:HGNC:10812|Ensembl:ENSG00000104205|Vega:OTTHUMG00000164561 +23679 SELENOWP1 HGNC:HGNC:10753 +23682 RAB38 MIM:606281|HGNC:HGNC:9776|Ensembl:ENSG00000123892|Vega:OTTHUMG00000167288 +23683 PRKD3 MIM:607077|HGNC:HGNC:9408|Ensembl:ENSG00000115825|Vega:OTTHUMG00000100961 +23685 PQBP4 HGNC:HGNC:9333 +23691 NNO1 MIM:600165|HGNC:HGNC:7862 +23694 MRX73 MIM:300355|HGNC:HGNC:7307 +23696 MRX70 HGNC:HGNC:7305 +23697 MRX69 HGNC:HGNC:7303 +23699 MRX67 HGNC:HGNC:7301 +23700 MRX66 HGNC:HGNC:7300 +23704 KCNE4 MIM:607775|HGNC:HGNC:6244|Ensembl:ENSG00000152049|Vega:OTTHUMG00000133161 +23705 CADM1 MIM:605686|HGNC:HGNC:5951|Ensembl:ENSG00000182985|Vega:OTTHUMG00000168202 +23706 IBGC1 MIM:213600|HGNC:HGNC:5336 +23708 GSPT2 MIM:300418|HGNC:HGNC:4622|Ensembl:ENSG00000189369|Vega:OTTHUMG00000021538 +23710 GABARAPL1 MIM:607420|HGNC:HGNC:4068|Ensembl:ENSG00000139112|Vega:OTTHUMG00000168411 +23713 DFNB27 MIM:605818|HGNC:HGNC:2833 +23714 DFNB26 MIM:605428|HGNC:HGNC:2832 +23719 DFNA30 MIM:606451|HGNC:HGNC:2802 +23720 DFNA29 HGNC:HGNC:2800 +23722 DFNA27 MIM:612431|HGNC:HGNC:2798 +23723 DFNA24 MIM:606282|HGNC:HGNC:2796 +23727 CFM2 HGNC:HGNC:1882 +23729 SHPK MIM:605060|HGNC:HGNC:1492|Ensembl:ENSG00000197417|Ensembl:ENSG00000262304|Vega:OTTHUMG00000090694|Vega:OTTHUMG00000177650 +23731 TMEM245 HGNC:HGNC:1363|Ensembl:ENSG00000106771|Vega:OTTHUMG00000020469 +23732 FRRS1L MIM:604574|HGNC:HGNC:1362|Ensembl:ENSG00000260230|Vega:OTTHUMG00000020468 +23738 OFD1P17 HGNC:HGNC:1332 +23739 C3CER1 HGNC:HGNC:1320 +23741 EID1 MIM:605894|HGNC:HGNC:1191|Ensembl:ENSG00000255302|Vega:OTTHUMG00000165911 +23742 NPAP1 MIM:610922|HGNC:HGNC:1190|Ensembl:ENSG00000185823|Vega:OTTHUMG00000129179 +23743 BHMT2 MIM:605932|HGNC:HGNC:1048|Ensembl:ENSG00000132840|Vega:OTTHUMG00000108158 +23744 ATP5EP1 HGNC:HGNC:839 +23746 AIPL1 MIM:604392|HGNC:HGNC:359|Ensembl:ENSG00000129221|Vega:OTTHUMG00000102043 +23749 YME1L1P1 HGNC:HGNC:12844 +23751 TOP3BP1 HGNC:HGNC:11994 +23752 TSSK1A HGNC:HGNC:11400 +23753 SDF2L1 MIM:607551|HGNC:HGNC:10676|Ensembl:ENSG00000128228|Vega:OTTHUMG00000150820 +23754 RPL32P5 HGNC:HGNC:10338 +23755 SIRPAP1 HGNC:HGNC:9663 +23756 RPS24P1 HGNC:HGNC:10412 +23757 ARSFP1 HGNC:HGNC:722 +23758 SFPQP1 HGNC:HGNC:10775 +23759 PPIL2 MIM:607588|HGNC:HGNC:9261|Ensembl:ENSG00000100023|Vega:OTTHUMG00000191763 +23760 PITPNB MIM:606876|HGNC:HGNC:9002|Ensembl:ENSG00000180957|Vega:OTTHUMG00000150976 +23761 PISD MIM:612770|HGNC:HGNC:8999|Ensembl:ENSG00000241878|Vega:OTTHUMG00000030252 +23762 OSBP2 MIM:606729|HGNC:HGNC:8504|Ensembl:ENSG00000184792|Vega:OTTHUMG00000151153 +23764 MAFF MIM:604877|HGNC:HGNC:6780|Ensembl:ENSG00000185022|Vega:OTTHUMG00000151163 +23765 IL17RA MIM:605461|HGNC:HGNC:5985|Ensembl:ENSG00000177663|Vega:OTTHUMG00000150026 +23766 GABARAPL3 HGNC:HGNC:4069 +23767 FLRT3 MIM:604808|HGNC:HGNC:3762|Ensembl:ENSG00000125848|Vega:OTTHUMG00000031914 +23768 FLRT2 MIM:604807|HGNC:HGNC:3761|Ensembl:ENSG00000185070|Vega:OTTHUMG00000171372 +23769 FLRT1 MIM:604806|HGNC:HGNC:3760|Ensembl:ENSG00000126500|Vega:OTTHUMG00000167788 +23770 FKBP8 MIM:604840|HGNC:HGNC:3724|Ensembl:ENSG00000105701|Vega:OTTHUMG00000183368 +23771 DIANPH MIM:603933|HGNC:HGNC:2875 +23772 CSF2RBP1 HGNC:HGNC:2437 +23774 BRD1 MIM:604589|HGNC:HGNC:1102|Ensembl:ENSG00000100425|Vega:OTTHUMG00000150288 +23779 ARHGAP8 MIM:609405|HGNC:HGNC:677|Ensembl:ENSG00000241484|Ensembl:ENSG00000248405|Vega:OTTHUMG00000030234|Vega:OTTHUMG00000160954 +23780 APOL2 MIM:607252|HGNC:HGNC:619|Ensembl:ENSG00000128335|Vega:OTTHUMG00000150634 +23781 AP1B1P2 HGNC:HGNC:298 +23782 AP1B1P1 HGNC:HGNC:297|Ensembl:ENSG00000234479 +23783 ANKRD62P1-PARP4P3 HGNC:HGNC:42393 +23784 POTEH MIM:608913|HGNC:HGNC:133|Ensembl:ENSG00000198062|Vega:OTTHUMG00000140314 +23785 ABCD1P1 HGNC:HGNC:62 +23786 BCL2L13 HGNC:HGNC:17164|Ensembl:ENSG00000099968|Vega:OTTHUMG00000150088 +23787 MTCH1 MIM:610449|HGNC:HGNC:17586|Ensembl:ENSG00000137409|Vega:OTTHUMG00000014614 +23788 MTCH2 MIM:613221|HGNC:HGNC:17587|Ensembl:ENSG00000109919|Vega:OTTHUMG00000166926 +24137 KIF4A MIM:300521|HGNC:HGNC:13339|Ensembl:ENSG00000090889|Vega:OTTHUMG00000021775 +24138 IFIT5 MIM:616135|HGNC:HGNC:13328|Ensembl:ENSG00000152778|Vega:OTTHUMG00000018713 +24139 EML2 MIM:617494|HGNC:HGNC:18035|Ensembl:ENSG00000125746|Vega:OTTHUMG00000182127 +24140 FTSJ1 MIM:300499|HGNC:HGNC:13254|Ensembl:ENSG00000068438|Vega:OTTHUMG00000024118 +24141 LAMP5 MIM:614641|HGNC:HGNC:16097|Ensembl:ENSG00000125869|Vega:OTTHUMG00000031851 +24142 NAT6 MIM:607073|HGNC:HGNC:30252|Ensembl:ENSG00000243477|Vega:OTTHUMG00000156939 +24144 TFIP11 MIM:612747|HGNC:HGNC:17165|Ensembl:ENSG00000100109|Vega:OTTHUMG00000150883 +24145 PANX1 MIM:608420|HGNC:HGNC:8599|Ensembl:ENSG00000110218|Vega:OTTHUMG00000167757 +24146 CLDN15 MIM:615778|HGNC:HGNC:2036|Ensembl:ENSG00000106404|Vega:OTTHUMG00000150512 +24147 FJX1 MIM:612206|HGNC:HGNC:17166|Ensembl:ENSG00000179431|Vega:OTTHUMG00000166310 +24148 PRPF6 MIM:613979|HGNC:HGNC:15860|Ensembl:ENSG00000101161|Vega:OTTHUMG00000033018 +24149 ZNF318 MIM:617512|HGNC:HGNC:13578|Ensembl:ENSG00000171467|Vega:OTTHUMG00000014732 +24150 TP53TG3 MIM:617482|HGNC:HGNC:30759|Ensembl:ENSG00000183632|Vega:OTTHUMG00000176507 +25758 KIAA1549L MIM:612297|HGNC:HGNC:24836|Ensembl:ENSG00000110427|Vega:OTTHUMG00000150410 +25759 SHC2 MIM:605217|HGNC:HGNC:29869|Ensembl:ENSG00000129946|Vega:OTTHUMG00000180545 +25763 HYPM HGNC:HGNC:18417|Ensembl:ENSG00000187516|Vega:OTTHUMG00000033180 +25764 HYPK MIM:612784|HGNC:HGNC:18418|Ensembl:ENSG00000242028|Vega:OTTHUMG00000060146 +25766 PRPF40B HGNC:HGNC:25031|Ensembl:ENSG00000110844|Vega:OTTHUMG00000169568 +25769 SLC24A2 MIM:609838|HGNC:HGNC:10976|Ensembl:ENSG00000155886|Vega:OTTHUMG00000019646 +25770 C22orf31 HGNC:HGNC:26931|Ensembl:ENSG00000100249|Vega:OTTHUMG00000151011 +25771 TBC1D22A MIM:616879|HGNC:HGNC:1309|Ensembl:ENSG00000054611|Vega:OTTHUMG00000150332 +25774 GSTTP1 HGNC:HGNC:26930|Ensembl:ENSG00000276950 +25775 C22orf24 HGNC:HGNC:23051|Ensembl:ENSG00000128254 +25776 CBY1 MIM:607757|HGNC:HGNC:1307|Ensembl:ENSG00000100211|Vega:OTTHUMG00000150990 +25777 SUN2 MIM:613569|HGNC:HGNC:14210|Ensembl:ENSG00000100242|Vega:OTTHUMG00000151031 +25778 DSTYK MIM:612666|HGNC:HGNC:29043|Ensembl:ENSG00000133059|Vega:OTTHUMG00000037102 +25780 RASGRP3 MIM:609531|HGNC:HGNC:14545|Ensembl:ENSG00000152689|Vega:OTTHUMG00000152124 +25782 RAB3GAP2 MIM:609275|HGNC:HGNC:17168|Ensembl:ENSG00000118873|Vega:OTTHUMG00000037139 +25784 DGCR12 HGNC:HGNC:17225 +25786 DGCR11 HGNC:HGNC:17226|Ensembl:ENSG00000273311 +25787 DGCR9 HGNC:HGNC:17227|Ensembl:ENSG00000273032 +25788 RAD54B MIM:604289|HGNC:HGNC:17228|Ensembl:ENSG00000197275|Ensembl:ENSG00000265817|Vega:OTTHUMG00000133658 +25789 TMEM59L MIM:617096|HGNC:HGNC:13237|Ensembl:ENSG00000105696|Vega:OTTHUMG00000183113 +25790 CFAP45 MIM:605152|HGNC:HGNC:17229|Ensembl:ENSG00000213085|Vega:OTTHUMG00000035432 +25791 NGEF MIM:605991|HGNC:HGNC:7807|Ensembl:ENSG00000066248|Vega:OTTHUMG00000133272 +25792 CIZ1 MIM:611420|HGNC:HGNC:16744|Ensembl:ENSG00000148337|Vega:OTTHUMG00000020735 +25793 FBXO7 MIM:605648|HGNC:HGNC:13586|Ensembl:ENSG00000100225|Vega:OTTHUMG00000030674 +25794 FSCN2 MIM:607643|HGNC:HGNC:3960|Ensembl:ENSG00000186765|Vega:OTTHUMG00000167477 +25796 PGLS MIM:604951|HGNC:HGNC:8903|Ensembl:ENSG00000130313|Vega:OTTHUMG00000182879 +25797 QPCT MIM:607065|HGNC:HGNC:9753|Ensembl:ENSG00000115828|Vega:OTTHUMG00000100963 +25798 BRI3 MIM:615628|HGNC:HGNC:1109|Ensembl:ENSG00000164713|Vega:OTTHUMG00000154275 +25799 ZNF324 MIM:617477|HGNC:HGNC:14096|Ensembl:ENSG00000083812|Vega:OTTHUMG00000183540 +25800 SLC39A6 MIM:608731|HGNC:HGNC:18607|Ensembl:ENSG00000141424|Vega:OTTHUMG00000178965 +25801 GCA MIM:607030|HGNC:HGNC:15990|Ensembl:ENSG00000115271|Vega:OTTHUMG00000132057 +25802 LMOD1 MIM:602715|HGNC:HGNC:6647|Ensembl:ENSG00000163431|Vega:OTTHUMG00000035802 +25803 SPDEF MIM:608144|HGNC:HGNC:17257|Ensembl:ENSG00000124664|Vega:OTTHUMG00000014548 +25804 LSM4 MIM:607284|HGNC:HGNC:17259|Ensembl:ENSG00000130520|Vega:OTTHUMG00000183357 +25805 BAMBI MIM:604444|HGNC:HGNC:30251|Ensembl:ENSG00000095739|Vega:OTTHUMG00000017874 +25806 VAX2 MIM:604295|HGNC:HGNC:12661|Ensembl:ENSG00000116035|Vega:OTTHUMG00000129714 +25807 RHBDD3 HGNC:HGNC:1308|Ensembl:ENSG00000100263|Vega:OTTHUMG00000151032 +25809 TTLL1 MIM:608955|HGNC:HGNC:1312|Ensembl:ENSG00000100271|Vega:OTTHUMG00000150699 +25812 POM121L1P HGNC:HGNC:16439 +25813 SAMM50 MIM:612058|HGNC:HGNC:24276|Ensembl:ENSG00000100347|Vega:OTTHUMG00000150557 +25814 ATXN10 MIM:611150|HGNC:HGNC:10549|Ensembl:ENSG00000130638|Vega:OTTHUMG00000150451 +25816 TNFAIP8 MIM:612111|HGNC:HGNC:17260|Ensembl:ENSG00000145779|Vega:OTTHUMG00000162949 +25817 FAM19A5 MIM:617499|HGNC:HGNC:21592|Ensembl:ENSG00000219438|Vega:OTTHUMG00000150308 +25818 KLK5 MIM:605643|HGNC:HGNC:6366|Ensembl:ENSG00000167754|Vega:OTTHUMG00000183097 +25819 NOCT MIM:608468|HGNC:HGNC:14254|Ensembl:ENSG00000151014|Vega:OTTHUMG00000161271 +25820 ARIH1 MIM:605624|HGNC:HGNC:689|Ensembl:ENSG00000166233|Vega:OTTHUMG00000133474 +25821 MTO1 MIM:614667|HGNC:HGNC:19261|Ensembl:ENSG00000135297|Vega:OTTHUMG00000015032 +25822 DNAJB5 MIM:611328|HGNC:HGNC:14887|Ensembl:ENSG00000137094|Vega:OTTHUMG00000019840 +25823 TPSG1 MIM:609341|HGNC:HGNC:14134|Ensembl:ENSG00000116176|Vega:OTTHUMG00000090466 +25824 PRDX5 MIM:606583|HGNC:HGNC:9355|Ensembl:ENSG00000126432|Vega:OTTHUMG00000168805 +25825 BACE2 MIM:605668|HGNC:HGNC:934|Ensembl:ENSG00000182240|Vega:OTTHUMG00000086742 +25826 SNORD82 MIM:611133|HGNC:HGNC:10240|Ensembl:ENSG00000202400 +25827 FBXL2 MIM:605652|HGNC:HGNC:13598|Ensembl:ENSG00000153558|Vega:OTTHUMG00000130745 +25828 TXN2 MIM:609063|HGNC:HGNC:17772|Ensembl:ENSG00000100348|Vega:OTTHUMG00000150596 +25829 TMEM184B HGNC:HGNC:1310|Ensembl:ENSG00000198792|Vega:OTTHUMG00000030557 +25830 SULT4A1 MIM:608359|HGNC:HGNC:14903|Ensembl:ENSG00000130540|Vega:OTTHUMG00000141314 +25831 HECTD1 HGNC:HGNC:20157|Ensembl:ENSG00000092148|Vega:OTTHUMG00000170670 +25832 NBPF14 MIM:614003|HGNC:HGNC:25232|Ensembl:ENSG00000270629|Vega:OTTHUMG00000188198 +25833 POU2F3 MIM:607394|HGNC:HGNC:19864|Ensembl:ENSG00000137709|Vega:OTTHUMG00000166140 +25834 MGAT4C MIM:607385|HGNC:HGNC:30871|Ensembl:ENSG00000182050|Vega:OTTHUMG00000169846 +25836 NIPBL MIM:608667|HGNC:HGNC:28862|Ensembl:ENSG00000164190|Vega:OTTHUMG00000090795 +25837 RAB26 MIM:605455|HGNC:HGNC:14259|Ensembl:ENSG00000167964|Vega:OTTHUMG00000128829 +25839 COG4 MIM:606976|HGNC:HGNC:18620|Ensembl:ENSG00000103051|Vega:OTTHUMG00000128515 +25840 METTL7A HGNC:HGNC:24550|Ensembl:ENSG00000185432|Vega:OTTHUMG00000169484 +25841 ABTB2 HGNC:HGNC:23842|Ensembl:ENSG00000166016|Vega:OTTHUMG00000044382 +25842 ASF1A MIM:609189|HGNC:HGNC:20995|Ensembl:ENSG00000111875|Vega:OTTHUMG00000015470 +25843 MOB4 MIM:609361|HGNC:HGNC:17261|Ensembl:ENSG00000115540|Vega:OTTHUMG00000132748 +25844 YIPF3 MIM:609775|HGNC:HGNC:21023|Ensembl:ENSG00000137207|Vega:OTTHUMG00000014738 +25845 PP7080 Ensembl:ENSG00000188242 +25847 ANAPC13 MIM:614484|HGNC:HGNC:24540|Ensembl:ENSG00000129055|Vega:OTTHUMG00000159803 +25849 PARM1 HGNC:HGNC:24536|Ensembl:ENSG00000169116|Vega:OTTHUMG00000160827 +25850 ZNF345 HGNC:HGNC:16367|Ensembl:ENSG00000251247|Vega:OTTHUMG00000048162 +25851 TECPR1 MIM:614781|HGNC:HGNC:22214|Ensembl:ENSG00000205356|Vega:OTTHUMG00000154273 +25852 ARMC8 HGNC:HGNC:24999|Ensembl:ENSG00000114098|Vega:OTTHUMG00000159821 +25853 DCAF12 HGNC:HGNC:19911|Ensembl:ENSG00000198876|Vega:OTTHUMG00000019806 +25854 FAM149A HGNC:HGNC:24527|Ensembl:ENSG00000109794|Vega:OTTHUMG00000160565 +25855 BRMS1 MIM:606259|HGNC:HGNC:17262|Ensembl:ENSG00000174744|Vega:OTTHUMG00000167081 +25858 CATSPERZ MIM:617511|HGNC:HGNC:19231|Ensembl:ENSG00000219435 +25859 PART1 MIM:604991|HGNC:HGNC:17263|Ensembl:ENSG00000152931 +25861 WHRN MIM:607928|HGNC:HGNC:16361|Ensembl:ENSG00000095397|Vega:OTTHUMG00000020539 +25862 USP49 HGNC:HGNC:20078|Ensembl:ENSG00000164663|Vega:OTTHUMG00000014688 +25864 ABHD14A HGNC:HGNC:24538|Ensembl:ENSG00000248487|Vega:OTTHUMG00000157818 +25865 PRKD2 MIM:607074|HGNC:HGNC:17293|Ensembl:ENSG00000105287|Vega:OTTHUMG00000183431 +25870 SUMF2 MIM:607940|HGNC:HGNC:20415|Ensembl:ENSG00000129103|Vega:OTTHUMG00000129373 +25871 NEPRO MIM:617089|HGNC:HGNC:24496|Ensembl:ENSG00000163608|Vega:OTTHUMG00000159286 +25873 RPL36 HGNC:HGNC:13631|Ensembl:ENSG00000130255|Vega:OTTHUMG00000178585 +25874 MPC2 MIM:614737|HGNC:HGNC:24515|Ensembl:ENSG00000143158|Vega:OTTHUMG00000034570 +25875 LETMD1 HGNC:HGNC:24241|Ensembl:ENSG00000050426|Vega:OTTHUMG00000169538 +25876 SPEF1 MIM:610674|HGNC:HGNC:15874|Ensembl:ENSG00000101222|Vega:OTTHUMG00000031756 +25878 MXRA5 MIM:300938|HGNC:HGNC:7539|Ensembl:ENSG00000101825|Vega:OTTHUMG00000021083 +25879 DCAF13 MIM:616196|HGNC:HGNC:24535|Ensembl:ENSG00000164934|Vega:OTTHUMG00000164888 +25880 TMEM186 HGNC:HGNC:24530|Ensembl:ENSG00000184857|Vega:OTTHUMG00000129696 +25884 CHRDL2 MIM:613127|HGNC:HGNC:24168|Ensembl:ENSG00000054938|Vega:OTTHUMG00000165623 +25885 POLR1A MIM:616404|HGNC:HGNC:17264|Ensembl:ENSG00000068654|Vega:OTTHUMG00000153165 +25886 POC1A MIM:614783|HGNC:HGNC:24488|Ensembl:ENSG00000164087|Vega:OTTHUMG00000157817 +25888 ZNF473 HGNC:HGNC:23239|Ensembl:ENSG00000142528|Vega:OTTHUMG00000183054 +25890 ABI3BP MIM:606279|HGNC:HGNC:17265|Ensembl:ENSG00000154175|Vega:OTTHUMG00000159094 +25891 PAMR1 HGNC:HGNC:24554|Ensembl:ENSG00000149090|Vega:OTTHUMG00000166328 +25893 TRIM58 HGNC:HGNC:24150|Ensembl:ENSG00000162722|Vega:OTTHUMG00000040203 +25894 PLEKHG4 MIM:609526|HGNC:HGNC:24501|Ensembl:ENSG00000196155|Vega:OTTHUMG00000172936 +25895 EEF1AKMT3 MIM:615258|HGNC:HGNC:24936|Ensembl:ENSG00000123427|Vega:OTTHUMG00000170459 +25896 INTS7 MIM:611350|HGNC:HGNC:24484|Ensembl:ENSG00000143493|Vega:OTTHUMG00000037119 +25897 RNF19A MIM:607119|HGNC:HGNC:13432|Ensembl:ENSG00000034677|Vega:OTTHUMG00000164707 +25898 RCHY1 MIM:607680|HGNC:HGNC:17479|Ensembl:ENSG00000163743|Vega:OTTHUMG00000130105 +25900 IFFO1 MIM:610495|HGNC:HGNC:24970|Ensembl:ENSG00000010295|Vega:OTTHUMG00000141264 +25901 CCDC28A MIM:615353|HGNC:HGNC:21098|Ensembl:ENSG00000024862|Vega:OTTHUMG00000015683 +25902 MTHFD1L MIM:611427|HGNC:HGNC:21055|Ensembl:ENSG00000120254|Vega:OTTHUMG00000015828 +25903 OLFML2B HGNC:HGNC:24558|Ensembl:ENSG00000162745|Vega:OTTHUMG00000024047 +25904 CNOT10 HGNC:HGNC:23817|Ensembl:ENSG00000182973|Vega:OTTHUMG00000130748 +25906 ANAPC15 MIM:614717|HGNC:HGNC:24531|Ensembl:ENSG00000110200|Vega:OTTHUMG00000167865 +25907 TMEM158 HGNC:HGNC:30293|Ensembl:ENSG00000249992|Vega:OTTHUMG00000160317 +25909 AHCTF1 MIM:610853|HGNC:HGNC:24618|Ensembl:ENSG00000153207|Vega:OTTHUMG00000040706 +25911 DPCD MIM:616467|HGNC:HGNC:24542|Ensembl:ENSG00000166171|Vega:OTTHUMG00000018934 +25912 C1orf43 MIM:617428|HGNC:HGNC:29876|Ensembl:ENSG00000143612|Vega:OTTHUMG00000035981 +25913 POT1 MIM:606478|HGNC:HGNC:17284|Ensembl:ENSG00000128513|Vega:OTTHUMG00000157194 +25914 RTTN MIM:610436|HGNC:HGNC:18654|Ensembl:ENSG00000176225|Vega:OTTHUMG00000178694 +25915 NDUFAF3 MIM:612911|HGNC:HGNC:29918|Ensembl:ENSG00000178057|Vega:OTTHUMG00000156773 +25917 THUMPD3 HGNC:HGNC:24493|Ensembl:ENSG00000134077|Vega:OTTHUMG00000097031 +25920 NELFB MIM:611180|HGNC:HGNC:24324|Ensembl:ENSG00000188986|Vega:OTTHUMG00000131778 +25921 ZDHHC5 MIM:614586|HGNC:HGNC:18472|Ensembl:ENSG00000156599|Vega:OTTHUMG00000167198 +25923 ATL3 MIM:609369|HGNC:HGNC:24526|Ensembl:ENSG00000184743|Vega:OTTHUMG00000167854 +25924 MYRIP MIM:611790|HGNC:HGNC:19156|Ensembl:ENSG00000170011|Vega:OTTHUMG00000131392 +25925 ZNF521 MIM:610974|HGNC:HGNC:24605|Ensembl:ENSG00000198795|Vega:OTTHUMG00000179511 +25926 NOL11 MIM:615366|HGNC:HGNC:24557|Ensembl:ENSG00000130935|Vega:OTTHUMG00000179777 +25927 CNRIP1 HGNC:HGNC:24546|Ensembl:ENSG00000119865|Vega:OTTHUMG00000129565 +25928 SOSTDC1 MIM:609675|HGNC:HGNC:21748|Ensembl:ENSG00000171243|Vega:OTTHUMG00000090807 +25929 GEMIN5 MIM:607005|HGNC:HGNC:20043|Ensembl:ENSG00000082516|Vega:OTTHUMG00000130189 +25930 PTPN23 MIM:606584|HGNC:HGNC:14406|Ensembl:ENSG00000076201|Vega:OTTHUMG00000133520 +25932 CLIC4 MIM:606536|HGNC:HGNC:13518|Ensembl:ENSG00000169504|Vega:OTTHUMG00000003327 +25934 NIPSNAP3A MIM:608871|HGNC:HGNC:23619|Ensembl:ENSG00000136783|Vega:OTTHUMG00000020413 +25936 NSL1 MIM:609174|HGNC:HGNC:24548|Ensembl:ENSG00000117697|Vega:OTTHUMG00000036806 +25937 WWTR1 MIM:607392|HGNC:HGNC:24042|Ensembl:ENSG00000018408|Vega:OTTHUMG00000159614 +25938 HEATR5A HGNC:HGNC:20276|Ensembl:ENSG00000129493|Vega:OTTHUMG00000169043 +25939 SAMHD1 MIM:606754|HGNC:HGNC:15925|Ensembl:ENSG00000101347|Vega:OTTHUMG00000032402 +25940 FAM98A HGNC:HGNC:24520|Ensembl:ENSG00000119812|Vega:OTTHUMG00000152152 +25941 TPGS2 HGNC:HGNC:24561|Ensembl:ENSG00000134779|Vega:OTTHUMG00000178075 +25942 SIN3A MIM:607776|HGNC:HGNC:19353|Ensembl:ENSG00000169375|Vega:OTTHUMG00000142834 +25943 C20orf194 MIM:614146|HGNC:HGNC:17721|Ensembl:ENSG00000088854|Vega:OTTHUMG00000031742 +25945 NECTIN3 MIM:607147|HGNC:HGNC:17664|Ensembl:ENSG00000177707|Vega:OTTHUMG00000159239 +25946 ZNF385A MIM:609124|HGNC:HGNC:17521|Ensembl:ENSG00000161642|Vega:OTTHUMG00000169840 +25948 KBTBD2 HGNC:HGNC:21751|Ensembl:ENSG00000170852|Vega:OTTHUMG00000152984 +25949 SYF2 MIM:607090|HGNC:HGNC:19824|Ensembl:ENSG00000117614|Vega:OTTHUMG00000043610 +25950 RWDD3 MIM:615875|HGNC:HGNC:21393|Ensembl:ENSG00000122481|Vega:OTTHUMG00000010910 +25953 PNKD MIM:609023|HGNC:HGNC:9153|Ensembl:ENSG00000127838|Vega:OTTHUMG00000133110 +25956 SEC31B MIM:610258|HGNC:HGNC:23197|Ensembl:ENSG00000075826|Vega:OTTHUMG00000019342 +25957 PNISR MIM:616653|HGNC:HGNC:21222|Ensembl:ENSG00000132424|Vega:OTTHUMG00000015262 +25959 KANK2 MIM:614610|HGNC:HGNC:29300|Ensembl:ENSG00000197256|Vega:OTTHUMG00000180799 +25960 ADGRA2 MIM:606823|HGNC:HGNC:17849|Ensembl:ENSG00000020181|Vega:OTTHUMG00000156182 +25961 NUDT13 MIM:609233|HGNC:HGNC:18827|Ensembl:ENSG00000166321|Vega:OTTHUMG00000018453 +25962 VIRMA MIM:616447|HGNC:HGNC:24500|Ensembl:ENSG00000164944|Vega:OTTHUMG00000164426 +25963 TMEM87A HGNC:HGNC:24522|Ensembl:ENSG00000103978|Vega:OTTHUMG00000172783 +25966 C2CD2 HGNC:HGNC:1266|Ensembl:ENSG00000157617|Vega:OTTHUMG00000086779 +25970 SH2B1 MIM:608937|HGNC:HGNC:30417|Ensembl:ENSG00000178188|Vega:OTTHUMG00000176590 +25972 UNC50 HGNC:HGNC:16046|Ensembl:ENSG00000115446|Vega:OTTHUMG00000130562 +25973 PARS2 MIM:612036|HGNC:HGNC:30563|Ensembl:ENSG00000162396|Vega:OTTHUMG00000009915 +25974 MMACHC MIM:609831|HGNC:HGNC:24525|Ensembl:ENSG00000132763|Vega:OTTHUMG00000007742 +25975 EGFL6 MIM:300239|HGNC:HGNC:3235|Ensembl:ENSG00000198759|Vega:OTTHUMG00000021155 +25976 TIPARP MIM:612480|HGNC:HGNC:23696|Ensembl:ENSG00000163659|Vega:OTTHUMG00000158646 +25977 NECAP1 MIM:611623|HGNC:HGNC:24539|Ensembl:ENSG00000089818|Vega:OTTHUMG00000168568 +25978 CHMP2B MIM:609512|HGNC:HGNC:24537|Ensembl:ENSG00000083937|Vega:OTTHUMG00000158982 +25979 DHRS7B MIM:616160|HGNC:HGNC:24547|Ensembl:ENSG00000109016|Vega:OTTHUMG00000178944 +25980 AAR2 MIM:617365|HGNC:HGNC:15886|Ensembl:ENSG00000131043|Vega:OTTHUMG00000032380 +25981 DNAH1 MIM:603332|HGNC:HGNC:2940|Ensembl:ENSG00000114841|Vega:OTTHUMG00000158378 +25983 NGDN MIM:610777|HGNC:HGNC:20271|Ensembl:ENSG00000129460|Vega:OTTHUMG00000171501 +25984 KRT23 MIM:606194|HGNC:HGNC:6438|Ensembl:ENSG00000108244|Vega:OTTHUMG00000133376 +25987 TSKU MIM:608015|HGNC:HGNC:28850|Ensembl:ENSG00000182704|Vega:OTTHUMG00000165238 +25988 HINFP MIM:607099|HGNC:HGNC:17850|Ensembl:ENSG00000172273|Vega:OTTHUMG00000166168 +25989 ULK3 MIM:613472|HGNC:HGNC:19703|Ensembl:ENSG00000140474|Vega:OTTHUMG00000173020 +25992 SNED1 MIM:616634|HGNC:HGNC:24696|Ensembl:ENSG00000162804|Vega:OTTHUMG00000151803 +25994 HIGD1A HGNC:HGNC:29527|Ensembl:ENSG00000181061|Vega:OTTHUMG00000190394 +25996 REXO2 MIM:607149|HGNC:HGNC:17851|Ensembl:ENSG00000076043|Vega:OTTHUMG00000168271 +25998 IBTK MIM:606457|HGNC:HGNC:17853|Ensembl:ENSG00000005700|Vega:OTTHUMG00000015102 +25999 CLIP3 MIM:607382|HGNC:HGNC:24314|Ensembl:ENSG00000105270|Vega:OTTHUMG00000181747 +26000 TBC1D10B MIM:613620|HGNC:HGNC:24510|Ensembl:ENSG00000169221|Vega:OTTHUMG00000132396 +26001 RNF167 MIM:610431|HGNC:HGNC:24544|Ensembl:ENSG00000108523|Vega:OTTHUMG00000099397 +26002 MOXD1 MIM:609000|HGNC:HGNC:21063|Ensembl:ENSG00000079931|Vega:OTTHUMG00000055853 +26003 GORASP2 MIM:608693|HGNC:HGNC:17500|Ensembl:ENSG00000115806|Vega:OTTHUMG00000154072 +26005 C2CD3 MIM:615944|HGNC:HGNC:24564|Ensembl:ENSG00000168014|Vega:OTTHUMG00000168110 +26007 TKFC MIM:615844|HGNC:HGNC:24552|Ensembl:ENSG00000149476|Vega:OTTHUMG00000168076 +26009 ZZZ3 HGNC:HGNC:24523|Ensembl:ENSG00000036549|Vega:OTTHUMG00000009652 +26010 SPATS2L MIM:613817|HGNC:HGNC:24574|Ensembl:ENSG00000196141|Vega:OTTHUMG00000154589 +26011 TENM4 MIM:610084|HGNC:HGNC:29945|Ensembl:ENSG00000149256|Vega:OTTHUMG00000166770 +26012 NSMF MIM:608137|HGNC:HGNC:29843|Ensembl:ENSG00000165802|Vega:OTTHUMG00000020989 +26013 L3MBTL1 MIM:608802|HGNC:HGNC:15905|Ensembl:ENSG00000185513|Vega:OTTHUMG00000032503 +26015 RPAP1 MIM:611475|HGNC:HGNC:24567|Ensembl:ENSG00000103932|Vega:OTTHUMG00000130342 +26017 FAM32A MIM:614554|HGNC:HGNC:24563|Ensembl:ENSG00000105058|Vega:OTTHUMG00000182279 +26018 LRIG1 MIM:608868|HGNC:HGNC:17360|Ensembl:ENSG00000144749|Vega:OTTHUMG00000158727 +26019 UPF2 MIM:605529|HGNC:HGNC:17854|Ensembl:ENSG00000151461|Vega:OTTHUMG00000017678 +26020 LRP10 MIM:609921|HGNC:HGNC:14553|Ensembl:ENSG00000197324|Vega:OTTHUMG00000028705 +26022 TMEM98 MIM:615949|HGNC:HGNC:24529|Ensembl:ENSG00000006042|Vega:OTTHUMG00000132882 +26024 PTCD1 MIM:614774|HGNC:HGNC:22198|Ensembl:ENSG00000106246|Vega:OTTHUMG00000154600 +26025 PCDHGA12 MIM:603059|HGNC:HGNC:8699|Ensembl:ENSG00000253159|Vega:OTTHUMG00000129611 +26027 ACOT11 MIM:606803|HGNC:HGNC:18156|Ensembl:ENSG00000162390|Vega:OTTHUMG00000009891 +26030 PLEKHG3 HGNC:HGNC:20364|Ensembl:ENSG00000126822|Vega:OTTHUMG00000029671 +26031 OSBPL3 MIM:606732|HGNC:HGNC:16370|Ensembl:ENSG00000070882|Vega:OTTHUMG00000023277 +26032 SUSD5 HGNC:HGNC:29061|Ensembl:ENSG00000173705|Vega:OTTHUMG00000155829 +26033 ATRNL1 MIM:612869|HGNC:HGNC:29063|Ensembl:ENSG00000107518|Vega:OTTHUMG00000019096 +26034 IPCEF1 HGNC:HGNC:21204|Ensembl:ENSG00000074706|Vega:OTTHUMG00000015872 +26035 GLCE MIM:612134|HGNC:HGNC:17855|Ensembl:ENSG00000138604|Vega:OTTHUMG00000172084 +26036 ZNF451 MIM:615708|HGNC:HGNC:21091|Ensembl:ENSG00000112200|Vega:OTTHUMG00000014916 +26037 SIPA1L1 MIM:617504|HGNC:HGNC:20284|Ensembl:ENSG00000197555|Vega:OTTHUMG00000171282 +26038 CHD5 MIM:610771|HGNC:HGNC:16816|Ensembl:ENSG00000116254|Vega:OTTHUMG00000000952 +26039 SS18L1 MIM:606472|HGNC:HGNC:15592|Ensembl:ENSG00000184402|Vega:OTTHUMG00000032902 +26040 SETBP1 MIM:611060|HGNC:HGNC:15573|Ensembl:ENSG00000152217|Vega:OTTHUMG00000132613 +26043 UBXN7 MIM:616379|HGNC:HGNC:29119|Ensembl:ENSG00000163960|Vega:OTTHUMG00000155639 +26045 LRRTM2 MIM:610868|HGNC:HGNC:19409|Ensembl:ENSG00000146006|Vega:OTTHUMG00000163535 +26046 LTN1 MIM:613083|HGNC:HGNC:13082|Ensembl:ENSG00000198862|Vega:OTTHUMG00000078803 +26047 CNTNAP2 MIM:604569|HGNC:HGNC:13830|Ensembl:ENSG00000174469|Vega:OTTHUMG00000152743 +26048 ZNF500 HGNC:HGNC:23716|Ensembl:ENSG00000103199|Vega:OTTHUMG00000176543 +26049 FAM169A MIM:615769|HGNC:HGNC:29138|Ensembl:ENSG00000198780|Vega:OTTHUMG00000162930 +26050 SLITRK5 MIM:609680|HGNC:HGNC:20295|Ensembl:ENSG00000165300|Vega:OTTHUMG00000017167 +26051 PPP1R16B MIM:613275|HGNC:HGNC:15850|Ensembl:ENSG00000101445|Vega:OTTHUMG00000032465 +26052 DNM3 MIM:611445|HGNC:HGNC:29125|Ensembl:ENSG00000197959|Vega:OTTHUMG00000034913 +26053 AUTS2 MIM:607270|HGNC:HGNC:14262|Ensembl:ENSG00000158321|Vega:OTTHUMG00000023865 +26054 SENP6 MIM:605003|HGNC:HGNC:20944|Ensembl:ENSG00000112701|Vega:OTTHUMG00000015060 +26056 RAB11FIP5 MIM:605536|HGNC:HGNC:24845|Ensembl:ENSG00000135631|Vega:OTTHUMG00000129779 +26057 ANKRD17 MIM:615929|HGNC:HGNC:23575|Ensembl:ENSG00000132466|Vega:OTTHUMG00000160826 +26058 GIGYF2 MIM:612003|HGNC:HGNC:11960|Ensembl:ENSG00000204120|Vega:OTTHUMG00000153237 +26059 ERC2 MIM:617250|HGNC:HGNC:31922|Ensembl:ENSG00000187672|Vega:OTTHUMG00000158390 +26060 APPL1 MIM:604299|HGNC:HGNC:24035|Ensembl:ENSG00000157500|Vega:OTTHUMG00000133756 +26061 HACL1 MIM:604300|HGNC:HGNC:17856|Ensembl:ENSG00000131373|Vega:OTTHUMG00000129862 +26062 HYALP1 HGNC:HGNC:5324 +26063 DECR2 MIM:615839|HGNC:HGNC:2754|Ensembl:ENSG00000242612|Vega:OTTHUMG00000047846 +26064 RAI14 MIM:606586|HGNC:HGNC:14873|Ensembl:ENSG00000039560|Vega:OTTHUMG00000162019 +26065 LSM14A MIM:610677|HGNC:HGNC:24489|Ensembl:ENSG00000257103|Vega:OTTHUMG00000180491 +26070 DKFZP434K028 Ensembl:ENSG00000124915 +26071 RTL8A HGNC:HGNC:24514|Ensembl:ENSG00000203950|Vega:OTTHUMG00000022466 +26073 POLDIP2 MIM:611519|HGNC:HGNC:23781|Ensembl:ENSG00000004142|Vega:OTTHUMG00000132065 +26074 CFAP61 HGNC:HGNC:15872|Ensembl:ENSG00000089101|Vega:OTTHUMG00000032006 +26077 DKFZP434H168 Ensembl:ENSG00000261439 +26080 FAM230C HGNC:HGNC:24482|Ensembl:ENSG00000279516 +26082 LINC02249 HGNC:HGNC:32351|Ensembl:ENSG00000225930 +26083 TBC1D29 HGNC:HGNC:24509|Ensembl:ENSG00000266733|Vega:OTTHUMG00000178857 +26084 ARHGEF26 MIM:617552|HGNC:HGNC:24490|Ensembl:ENSG00000114790|Vega:OTTHUMG00000159098 +26085 KLK13 MIM:605505|HGNC:HGNC:6361|Ensembl:ENSG00000167759|Vega:OTTHUMG00000182912 +26086 GPSM1 MIM:609491|HGNC:HGNC:17858|Ensembl:ENSG00000160360|Vega:OTTHUMG00000020930 +26088 GGA1 MIM:606004|HGNC:HGNC:17842|Ensembl:ENSG00000100083|Vega:OTTHUMG00000030985 +26090 ABHD12 MIM:613599|HGNC:HGNC:15868|Ensembl:ENSG00000100997|Vega:OTTHUMG00000032121 +26091 HERC4 MIM:609248|HGNC:HGNC:24521|Ensembl:ENSG00000148634|Vega:OTTHUMG00000018343 +26092 TOR1AIP1 MIM:614512|HGNC:HGNC:29456|Ensembl:ENSG00000143337|Vega:OTTHUMG00000035257 +26093 CCDC9 HGNC:HGNC:24560|Ensembl:ENSG00000105321|Vega:OTTHUMG00000183503 +26094 DCAF4 MIM:616372|HGNC:HGNC:20229|Ensembl:ENSG00000119599|Vega:OTTHUMG00000160542 +26095 PTPN20 MIM:610630|MIM:610631|HGNC:HGNC:23423|Ensembl:ENSG00000204179|Vega:OTTHUMG00000018094 +26097 CHTOP MIM:614206|HGNC:HGNC:24511|Ensembl:ENSG00000160679|Vega:OTTHUMG00000037052 +26098 EDRF1 HGNC:HGNC:24640|Ensembl:ENSG00000107938|Vega:OTTHUMG00000019233 +26099 SZRD1 HGNC:HGNC:30232|Ensembl:ENSG00000055070|Vega:OTTHUMG00000002217 +26100 WIPI2 MIM:609225|HGNC:HGNC:32225|Ensembl:ENSG00000157954|Vega:OTTHUMG00000121179 +26102 DKFZP434A062 Ensembl:ENSG00000262075 +26103 LRIT1 MIM:616103|HGNC:HGNC:23404|Ensembl:ENSG00000148602|Vega:OTTHUMG00000018632 +26108 PYGO1 MIM:606902|HGNC:HGNC:30256|Ensembl:ENSG00000171016|Vega:OTTHUMG00000132009 +26112 CCDC69 HGNC:HGNC:24487|Ensembl:ENSG00000198624|Vega:OTTHUMG00000130127 +26115 TANC2 MIM:615047|HGNC:HGNC:30212|Ensembl:ENSG00000170921|Vega:OTTHUMG00000179103 +26118 WSB1 MIM:610091|HGNC:HGNC:19221|Ensembl:ENSG00000109046|Vega:OTTHUMG00000132293 +26119 LDLRAP1 MIM:605747|HGNC:HGNC:18640|Ensembl:ENSG00000157978|Vega:OTTHUMG00000007386 +26121 PRPF31 MIM:606419|HGNC:HGNC:15446|Ensembl:ENSG00000105618|Vega:OTTHUMG00000066040 +26122 EPC2 MIM:611000|HGNC:HGNC:24543|Ensembl:ENSG00000135999|Vega:OTTHUMG00000153739 +26123 TCTN3 MIM:613847|HGNC:HGNC:24519|Ensembl:ENSG00000119977|Vega:OTTHUMG00000018814 +26127 FGFR1OP2 MIM:608858|HGNC:HGNC:23098|Ensembl:ENSG00000111790|Vega:OTTHUMG00000169231 +26128 KIF1BP MIM:609367|HGNC:HGNC:23419|Ensembl:ENSG00000198954|Vega:OTTHUMG00000018363 +26130 GAPVD1 MIM:611714|HGNC:HGNC:23375|Ensembl:ENSG00000165219|Vega:OTTHUMG00000020678 +26133 TRPC4AP MIM:608430|HGNC:HGNC:16181|Ensembl:ENSG00000100991|Vega:OTTHUMG00000032319 +26134 RALGAPA1P1 HGNC:HGNC:23203|Ensembl:ENSG00000229419 +26135 SERBP1 MIM:607378|HGNC:HGNC:17860|Ensembl:ENSG00000142864|Vega:OTTHUMG00000009372 +26136 TES MIM:606085|HGNC:HGNC:14620|Ensembl:ENSG00000135269|Vega:OTTHUMG00000023092 +26137 ZBTB20 MIM:606025|HGNC:HGNC:13503|Ensembl:ENSG00000181722|Vega:OTTHUMG00000159366 +26138 LINC00588 HGNC:HGNC:24494|Ensembl:ENSG00000215117 +26140 TTLL3 HGNC:HGNC:24483|Ensembl:ENSG00000214021|Vega:OTTHUMG00000128439 +26145 IRF2BP1 MIM:615331|HGNC:HGNC:21728|Ensembl:ENSG00000170604|Vega:OTTHUMG00000182485 +26146 TRAF3IP1 MIM:607380|HGNC:HGNC:17861|Ensembl:ENSG00000204104|Vega:OTTHUMG00000152872 +26147 PHF19 MIM:609740|HGNC:HGNC:24566|Ensembl:ENSG00000119403|Vega:OTTHUMG00000020577 +26149 ZNF658 MIM:616290|HGNC:HGNC:25226|Ensembl:ENSG00000274349|Vega:OTTHUMG00000188361 +26150 RIBC2 HGNC:HGNC:13241|Ensembl:ENSG00000128408|Vega:OTTHUMG00000151332 +26151 NAT9 HGNC:HGNC:23133|Ensembl:ENSG00000109065|Vega:OTTHUMG00000178870 +26152 ZNF337 HGNC:HGNC:15809|Ensembl:ENSG00000130684|Vega:OTTHUMG00000032131 +26153 KIF26A MIM:613231|HGNC:HGNC:20226|Ensembl:ENSG00000066735|Vega:OTTHUMG00000154986 +26154 ABCA12 MIM:607800|HGNC:HGNC:14637|Ensembl:ENSG00000144452|Vega:OTTHUMG00000154801 +26155 NOC2L MIM:610770|HGNC:HGNC:24517|Ensembl:ENSG00000188976|Vega:OTTHUMG00000040720 +26156 RSL1D1 MIM:615874|HGNC:HGNC:24534|Ensembl:ENSG00000171490|Vega:OTTHUMG00000129824 +26157 GIMAP2 MIM:608085|HGNC:HGNC:21789|Ensembl:ENSG00000106560|Vega:OTTHUMG00000157488 +26160 IFT172 MIM:607386|HGNC:HGNC:30391|Ensembl:ENSG00000138002|Vega:OTTHUMG00000128425 +26164 MTG2 MIM:610919|HGNC:HGNC:16239|Ensembl:ENSG00000101181|Vega:OTTHUMG00000032897 +26165 SPATA31A7 MIM:616584|HGNC:HGNC:32007|Ensembl:ENSG00000276040|Vega:OTTHUMG00000188536 +26166 RGS22 MIM:615650|HGNC:HGNC:24499|Ensembl:ENSG00000132554|Vega:OTTHUMG00000164802 +26167 PCDHB5 MIM:606331|HGNC:HGNC:8690|Ensembl:ENSG00000113209|Vega:OTTHUMG00000129616 +26168 SENP3 MIM:612844|HGNC:HGNC:17862|Ensembl:ENSG00000161956|Ensembl:ENSG00000277957|Vega:OTTHUMG00000178333|Vega:OTTHUMG00000178334 +26173 INTS1 MIM:611345|HGNC:HGNC:24555|Ensembl:ENSG00000164880|Vega:OTTHUMG00000151449 +26175 TMEM251 HGNC:HGNC:20218|Ensembl:ENSG00000153485|Vega:OTTHUMG00000171265 +26184 OR1F2P HGNC:HGNC:8196|Ensembl:ENSG00000203581 +26188 OR1C1 HGNC:HGNC:8182|Ensembl:ENSG00000221888|Vega:OTTHUMG00000040198 +26189 OR1A2 HGNC:HGNC:8180|Ensembl:ENSG00000172150|Vega:OTTHUMG00000090638 +26190 FBXW2 MIM:609071|HGNC:HGNC:13608|Ensembl:ENSG00000119402|Vega:OTTHUMG00000020576 +26191 PTPN22 MIM:600716|HGNC:HGNC:9652|Ensembl:ENSG00000134242|Vega:OTTHUMG00000011936 +26205 GMEB2 MIM:607451|HGNC:HGNC:4371|Ensembl:ENSG00000101216|Vega:OTTHUMG00000032988 +26206 SPAG8 MIM:605731|HGNC:HGNC:14105|Ensembl:ENSG00000137098|Vega:OTTHUMG00000019875 +26207 PITPNC1 MIM:605134|HGNC:HGNC:21045|Ensembl:ENSG00000154217|Vega:OTTHUMG00000179602 +26211 OR2F1 MIM:608497|HGNC:HGNC:8246|Ensembl:ENSG00000213215|Vega:OTTHUMG00000157771 +26212 OR2B6 HGNC:HGNC:8241|Ensembl:ENSG00000124657|Vega:OTTHUMG00000014497 +26219 OR1J4 HGNC:HGNC:8211|Ensembl:ENSG00000239590|Vega:OTTHUMG00000020606 +26220 DGCR5 HGNC:HGNC:16757|Ensembl:ENSG00000283406 +26222 DGCR10 HGNC:HGNC:17864 +26223 FBXL21 MIM:609087|HGNC:HGNC:13600 +26224 FBXL3 MIM:605653|HGNC:HGNC:13599|Ensembl:ENSG00000005812|Vega:OTTHUMG00000017099 +26225 ARL5A MIM:608960|HGNC:HGNC:696|Ensembl:ENSG00000162980|Vega:OTTHUMG00000131887 +26226 FBXW4P1 HGNC:HGNC:13609|Ensembl:ENSG00000230701 +26227 PHGDH MIM:606879|HGNC:HGNC:8923|Ensembl:ENSG00000092621|Vega:OTTHUMG00000012100 +26228 STAP1 MIM:604298|HGNC:HGNC:24133|Ensembl:ENSG00000035720|Vega:OTTHUMG00000129304 +26229 B3GAT3 MIM:606374|HGNC:HGNC:923|Ensembl:ENSG00000149541|Vega:OTTHUMG00000167685 +26230 TIAM2 MIM:604709|HGNC:HGNC:11806|Ensembl:ENSG00000146426|Vega:OTTHUMG00000015880 +26231 LRRC29 HGNC:HGNC:13605|Ensembl:ENSG00000125122 +26232 FBXO2 MIM:607112|HGNC:HGNC:13581|Ensembl:ENSG00000116661|Vega:OTTHUMG00000002072 +26233 FBXL6 MIM:609076|HGNC:HGNC:13603|Ensembl:ENSG00000182325|Vega:OTTHUMG00000165169 +26234 FBXL5 MIM:605655|HGNC:HGNC:13602|Ensembl:ENSG00000118564|Vega:OTTHUMG00000097097 +26235 FBXL4 MIM:605654|HGNC:HGNC:13601|Ensembl:ENSG00000112234|Vega:OTTHUMG00000015259 +26238 LINC01558 HGNC:HGNC:21235|Ensembl:ENSG00000146521 +26239 LCE2B MIM:612610|HGNC:HGNC:16610|Ensembl:ENSG00000159455|Vega:OTTHUMG00000012404 +26240 FAM50B MIM:614686|HGNC:HGNC:18789|Ensembl:ENSG00000145945|Ensembl:ENSG00000238158|Vega:OTTHUMG00000014147 +26242 OR4C1P HGNC:HGNC:8292 +26245 OR2M4 HGNC:HGNC:8270|Ensembl:ENSG00000171180|Vega:OTTHUMG00000040456 +26246 OR2L2 HGNC:HGNC:8266|Ensembl:ENSG00000203663|Vega:OTTHUMG00000040214 +26247 OR2L1P HGNC:HGNC:8265|Ensembl:ENSG00000224227 +26248 OR2K2 HGNC:HGNC:8264|Ensembl:ENSG00000171133|Vega:OTTHUMG00000020488 +26249 KLHL3 MIM:605775|HGNC:HGNC:6354|Ensembl:ENSG00000146021|Vega:OTTHUMG00000129155 +26251 KCNG2 MIM:605696|HGNC:HGNC:6249|Ensembl:ENSG00000178342|Vega:OTTHUMG00000044541 +26253 CLEC4E MIM:609962|HGNC:HGNC:14555|Ensembl:ENSG00000166523|Vega:OTTHUMG00000168675 +26254 OPTC MIM:605127|HGNC:HGNC:8158|Ensembl:ENSG00000188770|Vega:OTTHUMG00000036100 +26255 PTTG3P HGNC:HGNC:13422|Ensembl:ENSG00000213005 +26256 CABYR MIM:612135|HGNC:HGNC:15569|Ensembl:ENSG00000154040|Vega:OTTHUMG00000037365 +26257 NKX2-8 MIM:603245|HGNC:HGNC:16364|Ensembl:ENSG00000136327|Vega:OTTHUMG00000028772 +26258 BLOC1S6 MIM:604310|HGNC:HGNC:8549|Ensembl:ENSG00000104164|Vega:OTTHUMG00000131477 +26259 FBXW8 MIM:609073|HGNC:HGNC:13597|Ensembl:ENSG00000174989|Vega:OTTHUMG00000169329 +26260 FBXO25 MIM:609098|HGNC:HGNC:13596|Ensembl:ENSG00000147364|Vega:OTTHUMG00000090341 +26261 FBXO24 MIM:609097|HGNC:HGNC:13595|Ensembl:ENSG00000106336|Vega:OTTHUMG00000159543 +26262 TSPAN17 HGNC:HGNC:13594|Ensembl:ENSG00000048140|Vega:OTTHUMG00000163230 +26263 FBXO22 MIM:609096|HGNC:HGNC:13593|Ensembl:ENSG00000167196|Vega:OTTHUMG00000142841 +26266 SLC13A4 MIM:604309|HGNC:HGNC:15827|Ensembl:ENSG00000164707|Vega:OTTHUMG00000155539 +26267 FBXO10 MIM:609092|HGNC:HGNC:13589|Ensembl:ENSG00000147912|Ensembl:ENSG00000256966|Vega:OTTHUMG00000019926 +26268 FBXO9 MIM:609091|HGNC:HGNC:13588|Ensembl:ENSG00000112146|Vega:OTTHUMG00000014869 +26269 FBXO8 MIM:605649|HGNC:HGNC:13587|Ensembl:ENSG00000164117|Vega:OTTHUMG00000160746 +26270 FBXO6 MIM:605647|HGNC:HGNC:13585|Ensembl:ENSG00000116663|Vega:OTTHUMG00000002229 +26271 FBXO5 MIM:606013|HGNC:HGNC:13584|Ensembl:ENSG00000112029|Vega:OTTHUMG00000015854 +26272 FBXO4 MIM:609090|HGNC:HGNC:13583|Ensembl:ENSG00000151876|Vega:OTTHUMG00000094799 +26273 FBXO3 MIM:609089|HGNC:HGNC:13582|Ensembl:ENSG00000110429|Vega:OTTHUMG00000166244 +26275 HIBCH MIM:610690|HGNC:HGNC:4908|Ensembl:ENSG00000198130|Vega:OTTHUMG00000132673 +26276 VPS33B MIM:608552|HGNC:HGNC:12712|Ensembl:ENSG00000184056|Vega:OTTHUMG00000149835 +26277 TINF2 MIM:604319|HGNC:HGNC:11824|Ensembl:ENSG00000092330|Vega:OTTHUMG00000171849 +26278 SACS MIM:604490|HGNC:HGNC:10519|Ensembl:ENSG00000151835|Vega:OTTHUMG00000016562 +26279 PLA2G2D MIM:605630|HGNC:HGNC:9033|Ensembl:ENSG00000117215|Vega:OTTHUMG00000002701 +26280 IL1RAPL2 MIM:300277|HGNC:HGNC:5997|Ensembl:ENSG00000189108|Vega:OTTHUMG00000022141 +26281 FGF20 MIM:605558|HGNC:HGNC:3677|Ensembl:ENSG00000078579|Vega:OTTHUMG00000096964 +26284 ERAL1 MIM:607435|HGNC:HGNC:3424|Ensembl:ENSG00000132591|Vega:OTTHUMG00000132675 +26285 CLDN17 MIM:617005|HGNC:HGNC:2038|Ensembl:ENSG00000156282|Vega:OTTHUMG00000081873 +26286 ARFGAP3 MIM:612439|HGNC:HGNC:661|Ensembl:ENSG00000242247|Vega:OTTHUMG00000150718 +26287 ANKRD2 MIM:610734|HGNC:HGNC:495|Ensembl:ENSG00000165887|Vega:OTTHUMG00000018860 +26289 AK5 MIM:608009|HGNC:HGNC:365|Ensembl:ENSG00000154027|Vega:OTTHUMG00000009796 +26290 GALNT8 MIM:606250|HGNC:HGNC:4130|Ensembl:ENSG00000130035|Vega:OTTHUMG00000166188 +26291 FGF21 MIM:609436|HGNC:HGNC:3678|Ensembl:ENSG00000105550|Vega:OTTHUMG00000183326 +26292 MYCBP MIM:606535|HGNC:HGNC:7554|Ensembl:ENSG00000214114|Ensembl:ENSG00000274944|Vega:OTTHUMG00000000484|Vega:OTTHUMG00000187290 +26297 SERGEF MIM:606051|HGNC:HGNC:17499|Ensembl:ENSG00000129158|Vega:OTTHUMG00000166420 +26298 EHF MIM:605439|HGNC:HGNC:3246|Ensembl:ENSG00000135373|Vega:OTTHUMG00000166454 +26300 DYX4 HGNC:HGNC:3111 +26301 GBGT1 MIM:606074|HGNC:HGNC:20460|Ensembl:ENSG00000148288|Vega:OTTHUMG00000020853 +26307 PCDHA14 HGNC:HGNC:2163 +26322 OR4H6P HGNC:HGNC:8312 +26330 GAPDHS MIM:609169|HGNC:HGNC:24864|Ensembl:ENSG00000105679|Vega:OTTHUMG00000182298 +26333 OR7A17 HGNC:HGNC:8363|Ensembl:ENSG00000185385|Vega:OTTHUMG00000183415 +26335 OR7A15P HGNC:HGNC:8361 +26338 OR5L2 HGNC:HGNC:8351|Ensembl:ENSG00000205030|Vega:OTTHUMG00000166812 +26339 OR5K1 HGNC:HGNC:8349|Ensembl:ENSG00000232382|Vega:OTTHUMG00000160048 +26341 OR5H1 HGNC:HGNC:8346|Ensembl:ENSG00000231192|Vega:OTTHUMG00000160070 +26343 OR5E1P HGNC:HGNC:8342 +26353 HSPB8 MIM:608014|HGNC:HGNC:30171|Ensembl:ENSG00000152137|Vega:OTTHUMG00000168932 +26354 GNL3 MIM:608011|HGNC:HGNC:29931|Ensembl:ENSG00000163938|Vega:OTTHUMG00000158752 +26355 FAM162A MIM:608017|HGNC:HGNC:17865|Ensembl:ENSG00000114023|Vega:OTTHUMG00000159494 +26468 LHX6 MIM:608215|HGNC:HGNC:21735|Ensembl:ENSG00000106852|Vega:OTTHUMG00000020601 +26469 PTPN18 MIM:606587|HGNC:HGNC:9649|Ensembl:ENSG00000072135|Vega:OTTHUMG00000131630 +26470 SEZ6L2 MIM:616667|HGNC:HGNC:30844|Ensembl:ENSG00000174938|Vega:OTTHUMG00000132112 +26471 NUPR1 MIM:614812|HGNC:HGNC:29990|Ensembl:ENSG00000176046|Vega:OTTHUMG00000131764 +26472 PPP1R14B MIM:601140|HGNC:HGNC:9057|Ensembl:ENSG00000173457|Vega:OTTHUMG00000167846 +26473 OR7E16P HGNC:HGNC:8387 +26475 OR7E43P HGNC:HGNC:8417 +26476 OR10J1 HGNC:HGNC:8175|Ensembl:ENSG00000196184|Vega:OTTHUMG00000022737 +26478 OR7E53P HGNC:HGNC:8428 +26479 OR7E62P HGNC:HGNC:8438 +26492 OR8G2P HGNC:HGNC:8485 +26493 OR8B8 HGNC:HGNC:8477|Ensembl:ENSG00000197125|Vega:OTTHUMG00000165917 +26494 OR8G1 HGNC:HGNC:8484|Ensembl:ENSG00000197849|Vega:OTTHUMG00000189223 +26495 OR9A1P HGNC:HGNC:8486 +26496 OR10A3 HGNC:HGNC:8162|Ensembl:ENSG00000170683 +26497 OR10D3 HGNC:HGNC:8168 +26499 PLEK2 MIM:608007|HGNC:HGNC:19238|Ensembl:ENSG00000100558|Vega:OTTHUMG00000171247 +26502 NARF MIM:605349|HGNC:HGNC:29916|Ensembl:ENSG00000141562|Vega:OTTHUMG00000178844 +26503 SLC17A5 MIM:604322|HGNC:HGNC:10933|Ensembl:ENSG00000119899|Vega:OTTHUMG00000015039 +26504 CNNM4 MIM:607805|HGNC:HGNC:105|Ensembl:ENSG00000158158|Vega:OTTHUMG00000130532 +26505 CNNM3 MIM:607804|HGNC:HGNC:104|Ensembl:ENSG00000168763|Vega:OTTHUMG00000130531 +26507 CNNM1 MIM:607802|HGNC:HGNC:102|Ensembl:ENSG00000119946|Vega:OTTHUMG00000018881 +26508 HEYL MIM:609034|HGNC:HGNC:4882|Ensembl:ENSG00000163909|Vega:OTTHUMG00000000458 +26509 MYOF MIM:604603|HGNC:HGNC:3656|Ensembl:ENSG00000138119|Vega:OTTHUMG00000018772 +26511 CHIC2 MIM:604332|HGNC:HGNC:1935|Ensembl:ENSG00000109220|Vega:OTTHUMG00000102101 +26512 INTS6 MIM:604331|HGNC:HGNC:14879|Ensembl:ENSG00000102786|Vega:OTTHUMG00000016945 +26513 RPL34P2 HGNC:HGNC:10342 +26514 RPL34P1 HGNC:HGNC:10341 +26515 TIMM10B MIM:607388|HGNC:HGNC:4022|Ensembl:ENSG00000132286|Ensembl:ENSG00000283977|Vega:OTTHUMG00000179826 +26516 RPS5P1 HGNC:HGNC:10428 +26517 TIMM13 MIM:607383|HGNC:HGNC:11816|Ensembl:ENSG00000099800|Vega:OTTHUMG00000180432 +26519 TIMM10 MIM:602251|HGNC:HGNC:11814|Ensembl:ENSG00000134809|Vega:OTTHUMG00000167039 +26520 TIMM9 MIM:607384|HGNC:HGNC:11819|Ensembl:ENSG00000100575|Vega:OTTHUMG00000140322 +26521 TIMM8B MIM:606659|HGNC:HGNC:11818|Ensembl:ENSG00000150779|Vega:OTTHUMG00000162261 +26523 AGO1 MIM:606228|HGNC:HGNC:3262|Ensembl:ENSG00000092847|Vega:OTTHUMG00000007381 +26524 LATS2 MIM:604861|HGNC:HGNC:6515|Ensembl:ENSG00000150457|Vega:OTTHUMG00000016531 +26525 IL36RN MIM:605507|HGNC:HGNC:15561|Ensembl:ENSG00000136695|Vega:OTTHUMG00000131337 +26526 TSPAN16 HGNC:HGNC:30725|Ensembl:ENSG00000130167|Vega:OTTHUMG00000180833 +26528 DAZAP1 MIM:607430|HGNC:HGNC:2683|Ensembl:ENSG00000071626|Vega:OTTHUMG00000180058 +26529 OR12D2 HGNC:HGNC:8178|Ensembl:ENSG00000280236|Vega:OTTHUMG00000031049 +26530 OR12D1 HGNC:HGNC:8177 +26531 OR11A1 HGNC:HGNC:8176|Ensembl:ENSG00000204694|Vega:OTTHUMG00000031225 +26532 OR10H3 HGNC:HGNC:8174|Ensembl:ENSG00000171936|Vega:OTTHUMG00000182390 +26533 OR10G3 HGNC:HGNC:8171|Ensembl:ENSG00000169208|Vega:OTTHUMG00000168886 +26534 OR10G2 HGNC:HGNC:8170|Ensembl:ENSG00000255582|Vega:OTTHUMG00000168890 +26537 OR51A1P HGNC:HGNC:8316 +26538 OR10H2 HGNC:HGNC:8173|Ensembl:ENSG00000171942|Vega:OTTHUMG00000182389 +26539 OR10H1 HGNC:HGNC:8172|Ensembl:ENSG00000186723|Vega:OTTHUMG00000182285 +26540 OR10G1P HGNC:HGNC:8169 +26541 OR10D1P HGNC:HGNC:8166 +26548 ITGB1BP2 MIM:300332|HGNC:HGNC:6154|Ensembl:ENSG00000147166|Vega:OTTHUMG00000021793 +26574 AATF MIM:608463|HGNC:HGNC:19235|Ensembl:ENSG00000275700|Vega:OTTHUMG00000188458 +26575 RGS17 MIM:607191|HGNC:HGNC:14088|Ensembl:ENSG00000091844|Vega:OTTHUMG00000015858 +26576 SRPK3 HGNC:HGNC:11402|Ensembl:ENSG00000184343|Vega:OTTHUMG00000024207 +26577 PCOLCE2 MIM:607064|HGNC:HGNC:8739|Ensembl:ENSG00000163710|Vega:OTTHUMG00000159312 +26578 OSTF1 MIM:610180|HGNC:HGNC:8510|Ensembl:ENSG00000134996|Vega:OTTHUMG00000020033 +26579 MYEOV MIM:605625|HGNC:HGNC:7563|Ensembl:ENSG00000172927|Vega:OTTHUMG00000167836 +26580 BSCL2 MIM:606158|HGNC:HGNC:15832|Ensembl:ENSG00000168000|Vega:OTTHUMG00000150624 +26581 DUX5 MIM:611444|HGNC:HGNC:3083 +26582 DUX3 MIM:611443|HGNC:HGNC:3081 +26583 DUX4L8 MIM:611442|HGNC:HGNC:38670 +26584 DUX1 MIM:611441|HGNC:HGNC:3079 +26585 GREM1 MIM:603054|HGNC:HGNC:2001|Ensembl:ENSG00000166923|Vega:OTTHUMG00000129319 +26586 CKAP2 MIM:611569|HGNC:HGNC:1990|Ensembl:ENSG00000136108|Vega:OTTHUMG00000016967 +26589 MRPL46 MIM:611851|HGNC:HGNC:1192|Ensembl:ENSG00000259494|Vega:OTTHUMG00000148683 +26590 OR8B7P HGNC:HGNC:8476 +26591 OR8B6P HGNC:HGNC:8475 +26592 OR8B5P HGNC:HGNC:8474 +26595 OR8B2 HGNC:HGNC:8471|Ensembl:ENSG00000204293|Vega:OTTHUMG00000165982 +26608 TBL2 MIM:605842|HGNC:HGNC:11586|Ensembl:ENSG00000106638|Vega:OTTHUMG00000023427 +26609 VCX MIM:300229|HGNC:HGNC:12667|Ensembl:ENSG00000182583|Vega:OTTHUMG00000028608 +26610 ELP4 MIM:606985|HGNC:HGNC:1171|Ensembl:ENSG00000109911|Vega:OTTHUMG00000142919 +26614 OR7E66P HGNC:HGNC:8442 +26628 OR7E47P HGNC:HGNC:8421|Ensembl:ENSG00000257542|Ensembl:ENSG00000272724 +26637 OR7E36P HGNC:HGNC:8409 +26640 OR7E33P HGNC:HGNC:8406 +26644 OR7E29P HGNC:HGNC:8401 +26645 OR7E28P HGNC:HGNC:8400 +26647 OR7E25P HGNC:HGNC:8397 +26648 OR7E24 HGNC:HGNC:8396|Ensembl:ENSG00000237521|Vega:OTTHUMG00000179938 +26651 OR7E19P HGNC:HGNC:8390 +26656 OR7D1P HGNC:HGNC:8377 +26658 OR7C2 HGNC:HGNC:8374|Ensembl:ENSG00000127529|Vega:OTTHUMG00000183350 +26659 OR7A5 HGNC:HGNC:8368|Ensembl:ENSG00000188269|Vega:OTTHUMG00000183410 +26661 OR7A8P HGNC:HGNC:8371 +26664 OR7C1 HGNC:HGNC:8373|Ensembl:ENSG00000127530|Vega:OTTHUMG00000183411 +26668 OR7A3P HGNC:HGNC:8366 +26669 OR7A11P HGNC:HGNC:8357 +26679 OR4G3P HGNC:HGNC:8304 +26680 OR4G2P HGNC:HGNC:8303 +26681 OR4G1P HGNC:HGNC:8302 +26682 OR4F4 HGNC:HGNC:8301|Ensembl:ENSG00000177693|Vega:OTTHUMG00000172272 +26683 OR4F3 HGNC:HGNC:8300|Ensembl:ENSG00000230178|Vega:OTTHUMG00000162081 +26685 OR4F1P HGNC:HGNC:8298 +26686 OR4E2 HGNC:HGNC:8297|Ensembl:ENSG00000221977|Vega:OTTHUMG00000168979 +26687 OR4E1 HGNC:HGNC:8296 +26689 OR4D1 HGNC:HGNC:8293|Ensembl:ENSG00000141194|Vega:OTTHUMG00000178799 +26690 OR4B2P HGNC:HGNC:8291 +26692 OR2W1 HGNC:HGNC:8281|Ensembl:ENSG00000204704|Vega:OTTHUMG00000031048 +26693 OR2V1 HGNC:HGNC:8280|Ensembl:ENSG00000185372|Vega:OTTHUMG00000162118 +26694 OR2U2P HGNC:HGNC:8279 +26695 OR2U1P HGNC:HGNC:8278 +26696 OR2T1 HGNC:HGNC:8277|Ensembl:ENSG00000175143|Vega:OTTHUMG00000040450 +26701 OR2N1P HGNC:HGNC:8271 +26707 OR2J2 HGNC:HGNC:8260|Ensembl:ENSG00000204700|Vega:OTTHUMG00000031091 +26713 OR2H5P HGNC:HGNC:8256 +26716 OR2H1 HGNC:HGNC:8252|Ensembl:ENSG00000204688|Vega:OTTHUMG00000031050 +26717 OR2G1P HGNC:HGNC:8251 +26719 OR2E1P HGNC:HGNC:15507 +26735 OR1L3 HGNC:HGNC:8215|Ensembl:ENSG00000171481|Vega:OTTHUMG00000020619 +26737 OR1L1 HGNC:HGNC:8213|Ensembl:ENSG00000173679|Vega:OTTHUMG00000020618 +26740 OR1J2 HGNC:HGNC:8209|Ensembl:ENSG00000197233|Vega:OTTHUMG00000020604 +26742 OR1H1P HGNC:HGNC:8206 +26747 NUFIP1 MIM:604354|HGNC:HGNC:8057|Ensembl:ENSG00000083635|Vega:OTTHUMG00000016842 +26748 GAGE12I MIM:300637|HGNC:HGNC:4105 +26749 GAGE2E MIM:300736|HGNC:HGNC:31960 +26750 RPS6KC1 MIM:617517|HGNC:HGNC:10439|Ensembl:ENSG00000136643|Vega:OTTHUMG00000036926 +26751 SH3YL1 MIM:617314|HGNC:HGNC:29546|Ensembl:ENSG00000035115|Vega:OTTHUMG00000151359 +26762 HAVCR1 MIM:606518|HGNC:HGNC:17866|Ensembl:ENSG00000113249|Vega:OTTHUMG00000163466 +26765 SNORD12C HGNC:HGNC:10105|Ensembl:ENSG00000209042 +26766 RNU105C HGNC:HGNC:10104|Ensembl:ENSG00000199212 +26767 RNU105B HGNC:HGNC:10103|Ensembl:ENSG00000201348 +26768 SNORA73B MIM:603239|HGNC:HGNC:10116 +26769 SNORD81 HGNC:HGNC:10101 +26770 SNORD79 HGNC:HGNC:10100 +26771 SNORD102 HGNC:HGNC:10099|Ensembl:ENSG00000207500 +26772 SNORD4B HGNC:HGNC:10098|Ensembl:ENSG00000238597 +26773 SNORD4A HGNC:HGNC:10097|Ensembl:ENSG00000238578 +26774 SNORD80 HGNC:HGNC:10096 +26775 SNORA72 HGNC:HGNC:10234|Ensembl:ENSG00000207067 +26776 SNORA71B HGNC:HGNC:10233|Ensembl:ENSG00000235408 +26777 SNORA71A HGNC:HGNC:10232|Ensembl:ENSG00000225091 +26778 SNORA70 HGNC:HGNC:10231|Ensembl:ENSG00000207165 +26779 SNORA69 HGNC:HGNC:10226|Ensembl:ENSG00000206622 +26780 SNORA68 HGNC:HGNC:10225|Ensembl:ENSG00000207166 +26781 SNORA67 HGNC:HGNC:10224|Ensembl:ENSG00000277985 +26782 SNORA66 HGNC:HGNC:10223|Ensembl:ENSG00000207523 +26783 SNORA65 HGNC:HGNC:10222|Ensembl:ENSG00000201302 +26784 SNORA64 HGNC:HGNC:10221|Ensembl:ENSG00000207405 +26785 SNORD63 HGNC:HGNC:10220|Ensembl:ENSG00000206989 +26786 SNORD62A HGNC:HGNC:10219|Ensembl:ENSG00000235284 +26787 SNORD61 HGNC:HGNC:10218|Ensembl:ENSG00000206979 +26788 SNORD60 HGNC:HGNC:10217|Ensembl:ENSG00000206630|Ensembl:ENSG00000281010 +26789 SNORD59A HGNC:HGNC:10210|Ensembl:ENSG00000207031 +26790 SNORD58B HGNC:HGNC:10209|Ensembl:ENSG00000271982 +26791 SNORD58A HGNC:HGNC:10208|Ensembl:ENSG00000206602 +26792 SNORD57 HGNC:HGNC:10207|Ensembl:ENSG00000226572 +26793 SNORD56 HGNC:HGNC:10206|Ensembl:ENSG00000229686 +26795 SNORD54 HGNC:HGNC:10204|Ensembl:ENSG00000238650 +26796 SNORD53 HGNC:HGNC:10203|Ensembl:ENSG00000265145 +26797 SNORD52 HGNC:HGNC:10202|Ensembl:ENSG00000201754 +26798 SNORD51 HGNC:HGNC:10201|Ensembl:ENSG00000207047 +26799 SNORD50A MIM:613117|HGNC:HGNC:10200 +26800 SNORD49A HGNC:HGNC:10189|Ensembl:ENSG00000277370 +26801 SNORD48 HGNC:HGNC:10188|Ensembl:ENSG00000201823 +26802 SNORD47 HGNC:HGNC:10187 +26804 SNORD45B HGNC:HGNC:10185|Ensembl:ENSG00000201487 +26805 SNORD45A HGNC:HGNC:10184|Ensembl:ENSG00000207241 +26806 SNORD44 HGNC:HGNC:10183 +26807 SNORD43 MIM:611068|HGNC:HGNC:10182|Ensembl:ENSG00000263764 +26808 SNORD42B HGNC:HGNC:10181|Ensembl:ENSG00000238423 +26809 SNORD42A HGNC:HGNC:10180|Ensembl:ENSG00000238649 +26810 SNORD41 HGNC:HGNC:10179|Ensembl:ENSG00000209702 +26811 SNORD55 HGNC:HGNC:10205|Ensembl:ENSG00000264294 +26812 SNORD37 HGNC:HGNC:10166|Ensembl:ENSG00000206775 +26813 SNORD36C HGNC:HGNC:10165|Ensembl:ENSG00000252542 +26814 SNORD36B HGNC:HGNC:10164|Ensembl:ENSG00000200831 +26815 SNORD36A HGNC:HGNC:10163|Ensembl:ENSG00000199744 +26816 SNORD35A HGNC:HGNC:10162|Ensembl:ENSG00000200259 +26817 SNORD34 HGNC:HGNC:10161|Ensembl:ENSG00000202503 +26818 SNORD33 HGNC:HGNC:10160|Ensembl:ENSG00000199631 +26819 SNORD32A HGNC:HGNC:10159|Ensembl:ENSG00000201675 +26820 SNORD24 HGNC:HGNC:10146|Ensembl:ENSG00000206611 +26821 SNORA74A HGNC:HGNC:10119|Ensembl:ENSG00000200959 +26822 SNORD14A HGNC:HGNC:10113|Ensembl:ENSG00000272034 +26823 RNU12-2P HGNC:HGNC:10109 +26824 RNU11 HGNC:HGNC:10108|Ensembl:ENSG00000270103|Ensembl:ENSG00000274978 +26825 RNU6-50P HGNC:HGNC:10229 +26826 RNU6-6P HGNC:HGNC:10228 +26827 RNU6-1 MIM:180692|HGNC:HGNC:10227|Ensembl:ENSG00000206625 +26828 RNU5F-1 HGNC:HGNC:10216|Ensembl:ENSG00000199377 +26829 RNU5E-1 HGNC:HGNC:10215|Ensembl:ENSG00000199347 +26830 RNU5D-1 HGNC:HGNC:10214|Ensembl:ENSG00000200169 +26831 RNU5A-1 MIM:180691|HGNC:HGNC:10211|Ensembl:ENSG00000199568 +26832 RNU5B-1 HGNC:HGNC:10212|Ensembl:ENSG00000200156 +26834 RNU4-2 HGNC:HGNC:10193|Ensembl:ENSG00000202538 +26835 RNU4-1 HGNC:HGNC:10192|Ensembl:ENSG00000200795 +26838 RNU4-6P HGNC:HGNC:10199 +26839 RNU4-5P HGNC:HGNC:10198 +26840 RNU4-4P HGNC:HGNC:10197 +26841 RNU4-3P HGNC:HGNC:10196 +26842 SNORD3P4 HGNC:HGNC:10178 +26843 SNORD3P3 HGNC:HGNC:10177 +26844 SNORD3P2 HGNC:HGNC:10176 +26851 SNORD3B-1 HGNC:HGNC:10168|Ensembl:ENSG00000265185 +26852 RNU2-5P HGNC:HGNC:10155 +26853 RNU2-4P HGNC:HGNC:10154 +26854 RNU2-3P HGNC:HGNC:10153 +26855 RNU2-2P HGNC:HGNC:10152 +26858 RNU1-15P HGNC:HGNC:10140 +26859 RNU1-14P HGNC:HGNC:10139 +26860 RNU1-13P HGNC:HGNC:10138 +26861 RNU1-11P HGNC:HGNC:10137 +26863 RNVU1-18 HGNC:HGNC:37496|Ensembl:ENSG00000206737 +26864 RNVU1-7 HGNC:HGNC:37500|Ensembl:ENSG00000206585 +26865 RNU1-27P HGNC:HGNC:37497 +26866 RNU1-28P HGNC:HGNC:37498 +26869 RNU1-3 HGNC:HGNC:10130|Ensembl:ENSG00000207513 +26870 RNU1-2 HGNC:HGNC:10123|Ensembl:ENSG00000207005 +26871 RNU1-1 HGNC:HGNC:10120|Ensembl:ENSG00000206652 +26872 STEAP1 MIM:604415|HGNC:HGNC:11378|Ensembl:ENSG00000164647|Vega:OTTHUMG00000023006 +26873 OPLAH MIM:614243|HGNC:HGNC:8149|Ensembl:ENSG00000178814|Vega:OTTHUMG00000165435 +26952 SMR3A HGNC:HGNC:19216|Ensembl:ENSG00000109208|Vega:OTTHUMG00000160839 +26953 RANBP6 HGNC:HGNC:9851|Ensembl:ENSG00000137040|Vega:OTTHUMG00000019512 +26957 ABCD1P4 HGNC:HGNC:65 +26958 COPG2 MIM:604355|HGNC:HGNC:2237|Ensembl:ENSG00000158623|Vega:OTTHUMG00000155364 +26959 HBP1 MIM:616714|HGNC:HGNC:23200|Ensembl:ENSG00000105856|Vega:OTTHUMG00000157642 +26960 NBEA MIM:604889|HGNC:HGNC:7648|Ensembl:ENSG00000172915|Vega:OTTHUMG00000016724 +26973 CHORDC1 MIM:604353|HGNC:HGNC:14525|Ensembl:ENSG00000110172|Vega:OTTHUMG00000167305 +26974 ZNF285 HGNC:HGNC:13079|Ensembl:ENSG00000267508|Vega:OTTHUMG00000178848 +26978 PABPC1P3 HGNC:HGNC:8560 +26980 PABPC1P1 HGNC:HGNC:8558 +26982 ABCD1P3 HGNC:HGNC:64 +26983 ABCD1P2 HGNC:HGNC:63 +26984 SEC22A MIM:612442|HGNC:HGNC:20260|Ensembl:ENSG00000121542|Vega:OTTHUMG00000159495 +26985 AP3M1 MIM:610366|HGNC:HGNC:569|Ensembl:ENSG00000185009|Vega:OTTHUMG00000018497 +26986 PABPC1 MIM:604679|HGNC:HGNC:8554|Ensembl:ENSG00000070756|Vega:OTTHUMG00000164779 +26993 AKAP8L MIM:609475|HGNC:HGNC:29857|Ensembl:ENSG00000011243|Vega:OTTHUMG00000182446 +26994 RNF11 MIM:612598|HGNC:HGNC:10056|Ensembl:ENSG00000123091|Vega:OTTHUMG00000008190 +26995 TRUB2 MIM:610727|HGNC:HGNC:17170|Ensembl:ENSG00000167112|Vega:OTTHUMG00000020741 +26996 GPR160 HGNC:HGNC:23693|Ensembl:ENSG00000173890|Vega:OTTHUMG00000158776 +26998 FETUB MIM:605954|HGNC:HGNC:3658|Ensembl:ENSG00000090512|Vega:OTTHUMG00000156586 +26999 CYFIP2 MIM:606323|HGNC:HGNC:13760|Ensembl:ENSG00000055163|Vega:OTTHUMG00000163484 +27000 DNAJC2 MIM:605502|HGNC:HGNC:13192|Ensembl:ENSG00000105821|Vega:OTTHUMG00000157202 +27002 PAFAH1B1P2 HGNC:HGNC:8578 +27004 TCL6 MIM:604412|HGNC:HGNC:13463|Ensembl:ENSG00000187621 +27005 USP21 MIM:604729|HGNC:HGNC:12620|Ensembl:ENSG00000143258|Vega:OTTHUMG00000033154 +27006 FGF22 MIM:605831|HGNC:HGNC:3679|Ensembl:ENSG00000070388|Vega:OTTHUMG00000180591 +27010 TPK1 MIM:606370|HGNC:HGNC:17358|Ensembl:ENSG00000196511|Vega:OTTHUMG00000152774 +27012 KCNV1 MIM:608164|HGNC:HGNC:18861|Ensembl:ENSG00000164794|Vega:OTTHUMG00000165637 +27013 CNPPD1 HGNC:HGNC:25220|Ensembl:ENSG00000115649|Vega:OTTHUMG00000133132 +27018 BEX3 MIM:300361|HGNC:HGNC:13388|Ensembl:ENSG00000166681|Vega:OTTHUMG00000022099 +27019 DNAI1 MIM:604366|HGNC:HGNC:2954|Ensembl:ENSG00000122735|Vega:OTTHUMG00000019825 +27020 NPTN MIM:612820|HGNC:HGNC:17867|Ensembl:ENSG00000156642|Vega:OTTHUMG00000137586 +27022 FOXD3 MIM:611539|HGNC:HGNC:3804|Ensembl:ENSG00000187140|Vega:OTTHUMG00000009141 +27023 FOXB1 HGNC:HGNC:3799|Ensembl:ENSG00000171956|Vega:OTTHUMG00000172011 +27030 MLH3 MIM:604395|HGNC:HGNC:7128|Ensembl:ENSG00000119684|Vega:OTTHUMG00000171766 +27031 NPHP3 MIM:608002|HGNC:HGNC:7907|Ensembl:ENSG00000113971|Vega:OTTHUMG00000159713 +27032 ATP2C1 MIM:604384|HGNC:HGNC:13211|Ensembl:ENSG00000017260|Vega:OTTHUMG00000136802 +27033 ZBTB32 MIM:605859|HGNC:HGNC:16763|Ensembl:ENSG00000011590|Vega:OTTHUMG00000048118 +27034 ACAD8 MIM:604773|HGNC:HGNC:87|Ensembl:ENSG00000151498|Vega:OTTHUMG00000167177 +27035 NOX1 MIM:300225|HGNC:HGNC:7889|Ensembl:ENSG00000007952|Vega:OTTHUMG00000022007 +27036 SIGLEC7 MIM:604410|HGNC:HGNC:10876|Ensembl:ENSG00000168995|Vega:OTTHUMG00000182895 +27037 TRMT2A MIM:611151|HGNC:HGNC:24974|Ensembl:ENSG00000099899|Vega:OTTHUMG00000150454 +27038 ARVD6 MIM:604401 +27039 PKD2L2 MIM:604669|HGNC:HGNC:9012|Ensembl:ENSG00000078795|Vega:OTTHUMG00000163306 +27040 LAT MIM:602354|HGNC:HGNC:18874|Ensembl:ENSG00000213658|Vega:OTTHUMG00000131761 +27042 DIEXF HGNC:HGNC:28440|Ensembl:ENSG00000117597|Vega:OTTHUMG00000036654 +27043 PELP1 MIM:609455|HGNC:HGNC:30134|Ensembl:ENSG00000141456|Vega:OTTHUMG00000177831 +27044 SND1 MIM:602181|HGNC:HGNC:30646|Ensembl:ENSG00000197157|Vega:OTTHUMG00000157560 +27063 ANKRD1 MIM:609599|HGNC:HGNC:15819|Ensembl:ENSG00000148677|Vega:OTTHUMG00000018734 +27065 NSG1 MIM:607645|HGNC:HGNC:18790|Ensembl:ENSG00000168824|Vega:OTTHUMG00000160002 +27067 STAU2 MIM:605920|HGNC:HGNC:11371|Ensembl:ENSG00000040341|Vega:OTTHUMG00000164499 +27068 PPA2 MIM:609988|HGNC:HGNC:28883|Ensembl:ENSG00000138777|Vega:OTTHUMG00000128781 +27069 GHITM HGNC:HGNC:17281|Ensembl:ENSG00000165678|Vega:OTTHUMG00000018637 +27071 DAPP1 MIM:605768|HGNC:HGNC:16500|Ensembl:ENSG00000070190|Vega:OTTHUMG00000160974 +27072 VPS41 MIM:605485|HGNC:HGNC:12713|Ensembl:ENSG00000006715|Vega:OTTHUMG00000023629 +27074 LAMP3 MIM:605883|HGNC:HGNC:14582|Ensembl:ENSG00000078081|Vega:OTTHUMG00000158387 +27075 TSPAN13 MIM:613139|HGNC:HGNC:21643|Ensembl:ENSG00000106537|Vega:OTTHUMG00000022968 +27076 LYPD3 MIM:609484|HGNC:HGNC:24880|Ensembl:ENSG00000124466|Vega:OTTHUMG00000182696 +27077 B9D1 MIM:614144|HGNC:HGNC:24123|Ensembl:ENSG00000108641|Vega:OTTHUMG00000059586 +27079 RPUSD2 MIM:617488|HGNC:HGNC:24180|Ensembl:ENSG00000166133|Vega:OTTHUMG00000130031 +27085 MTBP MIM:605927|HGNC:HGNC:7417|Ensembl:ENSG00000172167|Vega:OTTHUMG00000165040 +27086 FOXP1 MIM:605515|HGNC:HGNC:3823|Ensembl:ENSG00000114861|Vega:OTTHUMG00000158803 +27087 B3GAT1 MIM:151290|HGNC:HGNC:921|Ensembl:ENSG00000109956|Vega:OTTHUMG00000167180 +27089 UQCRQ MIM:612080|HGNC:HGNC:29594|Ensembl:ENSG00000164405|Vega:OTTHUMG00000059836 +27090 ST6GALNAC4 MIM:606378|HGNC:HGNC:17846|Ensembl:ENSG00000136840|Vega:OTTHUMG00000020724 +27091 CACNG5 MIM:606405|HGNC:HGNC:1409|Ensembl:ENSG00000075429|Vega:OTTHUMG00000166468 +27092 CACNG4 MIM:606404|HGNC:HGNC:1408|Ensembl:ENSG00000075461|Vega:OTTHUMG00000179550 +27093 KCNMB3P1 HGNC:HGNC:6288 +27094 KCNMB3 MIM:605222|HGNC:HGNC:6287|Ensembl:ENSG00000171121|Vega:OTTHUMG00000157337 +27095 TRAPPC3 MIM:610955|HGNC:HGNC:19942|Ensembl:ENSG00000054116|Vega:OTTHUMG00000007664 +27097 TAF5L HGNC:HGNC:17304|Ensembl:ENSG00000135801|Vega:OTTHUMG00000039463 +27098 CLUL1 MIM:616990|HGNC:HGNC:2096|Ensembl:ENSG00000079101|Vega:OTTHUMG00000178252 +27099 SND1-IT1 HGNC:HGNC:24158|Ensembl:ENSG00000279078 +27101 CACYBP MIM:606186|HGNC:HGNC:30423|Ensembl:ENSG00000116161|Vega:OTTHUMG00000034941 +27102 EIF2AK1 MIM:613635|HGNC:HGNC:24921|Ensembl:ENSG00000086232|Vega:OTTHUMG00000090689 +27106 ARRDC2 HGNC:HGNC:25225|Ensembl:ENSG00000105643|Vega:OTTHUMG00000183483 +27107 ZBTB11 HGNC:HGNC:16740|Ensembl:ENSG00000066422|Vega:OTTHUMG00000159133 +27109 ATP5S HGNC:HGNC:18799|Ensembl:ENSG00000125375|Vega:OTTHUMG00000170866 +27111 SDCBP2 MIM:617358|HGNC:HGNC:15756|Ensembl:ENSG00000125775|Vega:OTTHUMG00000031661 +27112 FAM155B HGNC:HGNC:30701|Ensembl:ENSG00000130054|Vega:OTTHUMG00000021756 +27113 BBC3 MIM:605854|HGNC:HGNC:17868|Ensembl:ENSG00000105327|Vega:OTTHUMG00000183489 +27115 PDE7B MIM:604645|HGNC:HGNC:8792|Ensembl:ENSG00000171408|Vega:OTTHUMG00000015641 +27120 DKKL1 MIM:605418|HGNC:HGNC:16528|Ensembl:ENSG00000104901|Vega:OTTHUMG00000183171 +27121 DKK4 MIM:605417|HGNC:HGNC:2894|Ensembl:ENSG00000104371|Vega:OTTHUMG00000164167 +27122 DKK3 MIM:605416|HGNC:HGNC:2893|Ensembl:ENSG00000050165|Vega:OTTHUMG00000165709 +27123 DKK2 MIM:605415|HGNC:HGNC:2892|Ensembl:ENSG00000155011|Vega:OTTHUMG00000131216 +27124 INPP5J MIM:606481|HGNC:HGNC:8956|Ensembl:ENSG00000185133|Vega:OTTHUMG00000151206 +27125 AFF4 MIM:604417|HGNC:HGNC:17869|Ensembl:ENSG00000072364|Vega:OTTHUMG00000059838 +27127 SMC1B MIM:608685|HGNC:HGNC:11112|Ensembl:ENSG00000077935|Vega:OTTHUMG00000151334 +27128 CYTH4 MIM:606514|HGNC:HGNC:9505|Ensembl:ENSG00000100055|Vega:OTTHUMG00000150562 +27129 HSPB7 MIM:610692|HGNC:HGNC:5249|Ensembl:ENSG00000173641|Vega:OTTHUMG00000009531 +27130 INVS MIM:243305|HGNC:HGNC:17870|Ensembl:ENSG00000119509|Vega:OTTHUMG00000020364 +27131 SNX5 MIM:605937|HGNC:HGNC:14969|Ensembl:ENSG00000089006|Vega:OTTHUMG00000031953 +27132 CPNE7 MIM:605689|HGNC:HGNC:2320|Ensembl:ENSG00000178773|Vega:OTTHUMG00000138051 +27133 KCNH5 MIM:605716|HGNC:HGNC:6254|Ensembl:ENSG00000140015|Vega:OTTHUMG00000029041 +27134 TJP3 MIM:612689|HGNC:HGNC:11829|Ensembl:ENSG00000105289|Vega:OTTHUMG00000180872 +27136 MORC1 MIM:603205|HGNC:HGNC:7198|Ensembl:ENSG00000114487|Vega:OTTHUMG00000159209 +27141 CIDEB MIM:604441|HGNC:HGNC:1977|Ensembl:ENSG00000136305|Vega:OTTHUMG00000171555 +27143 PALD1 MIM:614656|HGNC:HGNC:23530|Ensembl:ENSG00000107719|Vega:OTTHUMG00000018411 +27145 FILIP1 MIM:607307|HGNC:HGNC:21015|Ensembl:ENSG00000118407|Vega:OTTHUMG00000015056 +27146 FAM184B HGNC:HGNC:29235|Ensembl:ENSG00000047662|Vega:OTTHUMG00000160287 +27147 DENND2A HGNC:HGNC:22212|Ensembl:ENSG00000146966|Vega:OTTHUMG00000157411 +27148 STK36 MIM:607652|HGNC:HGNC:17209|Ensembl:ENSG00000163482|Vega:OTTHUMG00000133079 +27151 CPAMD8 MIM:608841|HGNC:HGNC:23228|Ensembl:ENSG00000160111|Vega:OTTHUMG00000133549 +27152 INTU MIM:610621|HGNC:HGNC:29239|Ensembl:ENSG00000164066|Vega:OTTHUMG00000161202 +27153 ZNF777 HGNC:HGNC:22213|Ensembl:ENSG00000196453|Vega:OTTHUMG00000158967 +27154 BRPF3 MIM:616856|HGNC:HGNC:14256|Ensembl:ENSG00000096070|Vega:OTTHUMG00000014589 +27156 RSPH14 MIM:605663|HGNC:HGNC:13437|Ensembl:ENSG00000100218|Vega:OTTHUMG00000150602 +27158 NDOR1 MIM:606073|HGNC:HGNC:29838|Ensembl:ENSG00000188566|Vega:OTTHUMG00000020986 +27159 CHIA MIM:606080|HGNC:HGNC:17432|Ensembl:ENSG00000134216|Vega:OTTHUMG00000011165 +27160 INGX MIM:300452|HGNC:HGNC:6064|Ensembl:ENSG00000243468 +27161 AGO2 MIM:606229|HGNC:HGNC:3263|Ensembl:ENSG00000123908|Vega:OTTHUMG00000164232 +27163 NAAA MIM:607469|HGNC:HGNC:736|Ensembl:ENSG00000138744|Vega:OTTHUMG00000160855 +27164 SALL3 MIM:605079|HGNC:HGNC:10527|Ensembl:ENSG00000256463|Vega:OTTHUMG00000132896 +27165 GLS2 MIM:606365|HGNC:HGNC:29570|Ensembl:ENSG00000135423|Vega:OTTHUMG00000140379 +27166 PRELID1 MIM:605733|HGNC:HGNC:30255|Ensembl:ENSG00000169230|Vega:OTTHUMG00000130847 +27170 COTL1P1 HGNC:HGNC:2086 +27173 SLC39A1 MIM:604740|HGNC:HGNC:12876|Ensembl:ENSG00000143570|Vega:OTTHUMG00000037158 +27175 TUBG2 MIM:605785|HGNC:HGNC:12419|Ensembl:ENSG00000037042|Vega:OTTHUMG00000180640 +27177 IL36B MIM:605508|HGNC:HGNC:15564|Ensembl:ENSG00000136696|Vega:OTTHUMG00000131338 +27178 IL37 MIM:605510|HGNC:HGNC:15563|Ensembl:ENSG00000125571|Vega:OTTHUMG00000131345 +27179 IL36A MIM:605509|HGNC:HGNC:15562|Ensembl:ENSG00000136694|Vega:OTTHUMG00000153320 +27180 SIGLEC9 MIM:605640|HGNC:HGNC:10878|Ensembl:ENSG00000129450|Vega:OTTHUMG00000182894 +27181 SIGLEC8 MIM:605639|HGNC:HGNC:10877|Ensembl:ENSG00000105366|Vega:OTTHUMG00000182776 +27183 VPS4A MIM:609982|HGNC:HGNC:13488|Ensembl:ENSG00000132612|Ensembl:ENSG00000260914|Vega:OTTHUMG00000175589|Vega:OTTHUMG00000186022 +27184 DISC2 MIM:606271|HGNC:HGNC:2889 +27185 DISC1 MIM:605210|HGNC:HGNC:2888|Ensembl:ENSG00000162946|Vega:OTTHUMG00000037835 +27187 MOCS1P1 HGNC:HGNC:7191 +27189 IL17C MIM:604628|HGNC:HGNC:5983|Ensembl:ENSG00000124391|Vega:OTTHUMG00000173241 +27190 IL17B MIM:604627|HGNC:HGNC:5982|Ensembl:ENSG00000127743|Vega:OTTHUMG00000130051 +27192 TRAPPC2P6 HGNC:HGNC:10715 +27193 TRAPPC2P5 HGNC:HGNC:10714 +27194 TRAPPC2P4 HGNC:HGNC:10713 +27195 TRAPPC2P3 HGNC:HGNC:10712 +27196 TRAPPC2P2 HGNC:HGNC:10711 +27197 GPR82 MIM:300748|HGNC:HGNC:4533|Ensembl:ENSG00000171657|Vega:OTTHUMG00000021373 +27198 HCAR1 MIM:606923|HGNC:HGNC:4532|Ensembl:ENSG00000196917|Vega:OTTHUMG00000168863 +27199 OXGR1 MIM:606922|HGNC:HGNC:4531|Ensembl:ENSG00000165621|Vega:OTTHUMG00000017236 +27200 GPR79 HGNC:HGNC:4529 +27201 GPR78 MIM:606921|HGNC:HGNC:4528|Ensembl:ENSG00000155269|Vega:OTTHUMG00000128483 +27202 C5AR2 MIM:609949|HGNC:HGNC:4527|Ensembl:ENSG00000134830|Vega:OTTHUMG00000183505 +27229 TUBGCP4 MIM:609610|HGNC:HGNC:16691|Ensembl:ENSG00000137822|Vega:OTTHUMG00000176647 +27230 SERP1 HGNC:HGNC:10759|Ensembl:ENSG00000120742|Vega:OTTHUMG00000159769 +27231 NMRK2 MIM:608705|HGNC:HGNC:17871|Ensembl:ENSG00000077009|Vega:OTTHUMG00000181758 +27232 GNMT MIM:606628|HGNC:HGNC:4415|Ensembl:ENSG00000124713|Vega:OTTHUMG00000014712 +27233 SULT1C4 MIM:608357|HGNC:HGNC:11457|Ensembl:ENSG00000198075|Vega:OTTHUMG00000130958 +27235 COQ2 MIM:609825|HGNC:HGNC:25223|Ensembl:ENSG00000173085|Vega:OTTHUMG00000160940 +27236 ARFIP1 MIM:605928|HGNC:HGNC:21496|Ensembl:ENSG00000164144|Vega:OTTHUMG00000161468 +27237 ARHGEF16 HGNC:HGNC:15515|Ensembl:ENSG00000130762|Vega:OTTHUMG00000000625 +27238 GPKOW HGNC:HGNC:30677|Ensembl:ENSG00000068394|Vega:OTTHUMG00000021511 +27239 GPR162 HGNC:HGNC:16693|Ensembl:ENSG00000250510|Vega:OTTHUMG00000168368 +27240 SIT1 MIM:604964|HGNC:HGNC:17710|Ensembl:ENSG00000137078|Vega:OTTHUMG00000019867 +27241 BBS9 MIM:607968|HGNC:HGNC:30000|Ensembl:ENSG00000122507|Vega:OTTHUMG00000128659 +27242 TNFRSF21 MIM:605732|HGNC:HGNC:13469|Ensembl:ENSG00000146072|Vega:OTTHUMG00000014796 +27243 CHMP2A MIM:610893|HGNC:HGNC:30216|Ensembl:ENSG00000130724|Vega:OTTHUMG00000183547 +27244 SESN1 MIM:606103|HGNC:HGNC:21595|Ensembl:ENSG00000080546|Vega:OTTHUMG00000015338 +27245 AHDC1 MIM:615790|HGNC:HGNC:25230|Ensembl:ENSG00000126705|Vega:OTTHUMG00000003398 +27246 RNF115 HGNC:HGNC:18154|Ensembl:ENSG00000265491|Vega:OTTHUMG00000013758 +27247 NFU1 MIM:608100|HGNC:HGNC:16287|Ensembl:ENSG00000169599|Vega:OTTHUMG00000152668 +27248 ERLEC1 MIM:611229|HGNC:HGNC:25222|Ensembl:ENSG00000068912|Vega:OTTHUMG00000129281 +27249 MMADHC MIM:611935|HGNC:HGNC:25221|Ensembl:ENSG00000168288|Vega:OTTHUMG00000155558 +27250 PDCD4 MIM:608610|HGNC:HGNC:8763|Ensembl:ENSG00000150593|Vega:OTTHUMG00000019048 +27252 KLHL20 HGNC:HGNC:25056|Ensembl:ENSG00000076321|Vega:OTTHUMG00000040548 +27253 PCDH17 MIM:611760|HGNC:HGNC:14267|Ensembl:ENSG00000118946|Vega:OTTHUMG00000016992 +27254 CSDC2 HGNC:HGNC:30359|Ensembl:ENSG00000172346|Vega:OTTHUMG00000150967 +27255 CNTN6 MIM:607220|HGNC:HGNC:2176|Ensembl:ENSG00000134115|Vega:OTTHUMG00000119030 +27257 LSM1 MIM:607281|HGNC:HGNC:20472|Ensembl:ENSG00000175324|Vega:OTTHUMG00000164051 +27258 LSM3 MIM:607283|HGNC:HGNC:17874|Ensembl:ENSG00000170860|Vega:OTTHUMG00000129838 +27259 HPLH1 MIM:267700|HGNC:HGNC:23824 +27283 TINAG MIM:606749|HGNC:HGNC:14599|Ensembl:ENSG00000137251|Vega:OTTHUMG00000014893 +27284 SULT1B1 MIM:608436|HGNC:HGNC:17845|Ensembl:ENSG00000173597|Vega:OTTHUMG00000129407 +27285 TEKT2 MIM:608953|HGNC:HGNC:11725|Ensembl:ENSG00000092850|Vega:OTTHUMG00000007629 +27286 SRPX2 MIM:300642|HGNC:HGNC:30668|Ensembl:ENSG00000102359|Vega:OTTHUMG00000022003 +27287 VENTX MIM:607158|HGNC:HGNC:13639|Ensembl:ENSG00000151650|Vega:OTTHUMG00000019307 +27288 RBMXL2 MIM:605444|HGNC:HGNC:17886|Ensembl:ENSG00000170748|Vega:OTTHUMG00000165509 +27289 RND1 MIM:609038|HGNC:HGNC:18314|Ensembl:ENSG00000172602|Vega:OTTHUMG00000170400 +27290 SPINK4 MIM:613929|HGNC:HGNC:16646|Ensembl:ENSG00000122711|Vega:OTTHUMG00000019762 +27291 R3HCC1L HGNC:HGNC:23512|Ensembl:ENSG00000166024|Vega:OTTHUMG00000018873 +27292 DIMT1 MIM:612499|HGNC:HGNC:30217|Ensembl:ENSG00000086189|Vega:OTTHUMG00000131223 +27293 SMPDL3B HGNC:HGNC:21416|Ensembl:ENSG00000130768|Vega:OTTHUMG00000003910 +27294 DHDH MIM:606377|HGNC:HGNC:17887|Ensembl:ENSG00000104808|Vega:OTTHUMG00000165029 +27295 PDLIM3 MIM:605889|HGNC:HGNC:20767|Ensembl:ENSG00000154553|Vega:OTTHUMG00000160412 +27296 TP53TG5 MIM:617316|HGNC:HGNC:15856|Ensembl:ENSG00000124251|Vega:OTTHUMG00000032582 +27297 CRCP MIM:606121|HGNC:HGNC:17888|Ensembl:ENSG00000241258|Vega:OTTHUMG00000129519 +27299 ADAMDEC1 MIM:606393|HGNC:HGNC:16299|Ensembl:ENSG00000134028|Vega:OTTHUMG00000097858 +27300 ZNF544 HGNC:HGNC:16759|Ensembl:ENSG00000198131|Ensembl:ENSG00000283515|Vega:OTTHUMG00000183458|Vega:OTTHUMG00000183459 +27301 APEX2 MIM:300773|HGNC:HGNC:17889|Ensembl:ENSG00000169188|Vega:OTTHUMG00000021642 +27302 BMP10 MIM:608748|HGNC:HGNC:20869|Ensembl:ENSG00000163217|Vega:OTTHUMG00000129573 +27303 RBMS3 MIM:605786|HGNC:HGNC:13427|Ensembl:ENSG00000144642|Vega:OTTHUMG00000155699 +27304 MOCS3 MIM:609277|HGNC:HGNC:15765|Ensembl:ENSG00000124217|Vega:OTTHUMG00000032741 +27306 HPGDS MIM:602598|HGNC:HGNC:17890|Ensembl:ENSG00000163106|Vega:OTTHUMG00000130974 +27309 ZNF330 MIM:609550|HGNC:HGNC:15462|Ensembl:ENSG00000109445|Vega:OTTHUMG00000133413 +27314 RAB30 MIM:605693|HGNC:HGNC:9770|Ensembl:ENSG00000137502|Vega:OTTHUMG00000166973 +27315 PGAP2 MIM:615187|HGNC:HGNC:17893|Ensembl:ENSG00000148985|Vega:OTTHUMG00000012238 +27316 RBMX MIM:300199|HGNC:HGNC:9910|Ensembl:ENSG00000147274|Vega:OTTHUMG00000022517 +27319 BHLHE22 MIM:613483|HGNC:HGNC:11963|Ensembl:ENSG00000180828|Vega:OTTHUMG00000164386 +27320 TNRC18P2 HGNC:HGNC:34014 +27321 TNRC17 HGNC:HGNC:11961 +27324 TOX3 MIM:611416|HGNC:HGNC:11972|Ensembl:ENSG00000103460|Vega:OTTHUMG00000173222 +27327 TNRC6A MIM:610739|HGNC:HGNC:11969|Ensembl:ENSG00000090905|Vega:OTTHUMG00000096999 +27328 PCDH11X MIM:300246|HGNC:HGNC:8656|Ensembl:ENSG00000102290|Vega:OTTHUMG00000021965 +27329 ANGPTL3 MIM:604774|HGNC:HGNC:491|Ensembl:ENSG00000132855|Vega:OTTHUMG00000009146 +27330 RPS6KA6 MIM:300303|HGNC:HGNC:10435|Ensembl:ENSG00000072133|Vega:OTTHUMG00000021923 +27332 ZNF638 MIM:614349|HGNC:HGNC:17894|Ensembl:ENSG00000075292|Vega:OTTHUMG00000129735 +27333 GOLIM4 MIM:606805|HGNC:HGNC:15448|Ensembl:ENSG00000173905|Vega:OTTHUMG00000158554 +27334 P2RY10 MIM:300529|HGNC:HGNC:19906|Ensembl:ENSG00000078589|Vega:OTTHUMG00000021896 +27335 EIF3K MIM:609596|HGNC:HGNC:24656|Ensembl:ENSG00000178982|Vega:OTTHUMG00000180865 +27336 HTATSF1 MIM:300346|HGNC:HGNC:5276|Ensembl:ENSG00000102241|Vega:OTTHUMG00000022510 +27338 UBE2S MIM:610309|HGNC:HGNC:17895|Ensembl:ENSG00000108106|Vega:OTTHUMG00000180811 +27339 PRPF19 MIM:608330|HGNC:HGNC:17896|Ensembl:ENSG00000110107|Vega:OTTHUMG00000167798 +27340 UTP20 MIM:612822|HGNC:HGNC:17897|Ensembl:ENSG00000120800|Vega:OTTHUMG00000170270 +27341 RRP7A HGNC:HGNC:24286|Ensembl:ENSG00000189306|Vega:OTTHUMG00000150891 +27342 RABGEF1 MIM:609700|HGNC:HGNC:17676|Ensembl:ENSG00000154710|Ensembl:ENSG00000284461|Vega:OTTHUMG00000129547 +27343 POLL MIM:606343|HGNC:HGNC:9184|Ensembl:ENSG00000166169|Vega:OTTHUMG00000018933 +27344 PCSK1N MIM:300399|HGNC:HGNC:17301|Ensembl:ENSG00000102109|Vega:OTTHUMG00000034502 +27345 KCNMB4 MIM:605223|HGNC:HGNC:6289|Ensembl:ENSG00000135643|Vega:OTTHUMG00000167586 +27346 TMEM97 MIM:612912|HGNC:HGNC:28106|Ensembl:ENSG00000109084|Vega:OTTHUMG00000132497 +27347 STK39 MIM:607648|HGNC:HGNC:17717|Ensembl:ENSG00000198648|Vega:OTTHUMG00000133745 +27348 TOR1B MIM:608050|HGNC:HGNC:11995|Ensembl:ENSG00000136816|Vega:OTTHUMG00000020795 +27349 MCAT MIM:614479|HGNC:HGNC:29622|Ensembl:ENSG00000100294|Vega:OTTHUMG00000150704 +27350 APOBEC3C MIM:607750|HGNC:HGNC:17353|Ensembl:ENSG00000244509|Vega:OTTHUMG00000151087 +27351 DESI1 MIM:614637|HGNC:HGNC:24577|Ensembl:ENSG00000100418|Vega:OTTHUMG00000044632 +27352 SGSM3 MIM:610440|HGNC:HGNC:25228|Ensembl:ENSG00000100359|Vega:OTTHUMG00000151141 +27429 HTRA2 MIM:606441|HGNC:HGNC:14348|Ensembl:ENSG00000115317|Vega:OTTHUMG00000129957 +27430 MAT2B MIM:605527|HGNC:HGNC:6905|Ensembl:ENSG00000038274|Vega:OTTHUMG00000130379 +27433 TOR2A MIM:608052|HGNC:HGNC:11996|Ensembl:ENSG00000160404|Vega:OTTHUMG00000020706 +27434 POLM MIM:606344|HGNC:HGNC:9185|Ensembl:ENSG00000122678|Vega:OTTHUMG00000155353 +27436 EML4 MIM:607442|HGNC:HGNC:1316|Ensembl:ENSG00000143924|Vega:OTTHUMG00000128603 +27437 HSFY1P1 HGNC:HGNC:1846|Ensembl:ENSG00000229027 +27439 TMEM121B HGNC:HGNC:1844|Ensembl:ENSG00000183307|Vega:OTTHUMG00000030471 +27440 HDHD5 HGNC:HGNC:1843|Ensembl:ENSG00000069998|Vega:OTTHUMG00000150071 +27442 CECR3 HGNC:HGNC:1841|Ensembl:ENSG00000241832 +27443 CECR2 MIM:607576|HGNC:HGNC:1840|Ensembl:ENSG00000099954|Vega:OTTHUMG00000150072 +27445 PCLO MIM:604918|HGNC:HGNC:13406|Ensembl:ENSG00000186472|Vega:OTTHUMG00000154853 +28227 PPP2R3B MIM:300339|HGNC:HGNC:13417|Ensembl:ENSG00000167393|Vega:OTTHUMG00000021052 +28231 SLCO4A1 MIM:612436|HGNC:HGNC:10953|Ensembl:ENSG00000101187|Vega:OTTHUMG00000032923 +28232 SLCO3A1 MIM:612435|HGNC:HGNC:10952|Ensembl:ENSG00000176463|Vega:OTTHUMG00000149846 +28234 SLCO1B3 MIM:605495|HGNC:HGNC:10961|Ensembl:ENSG00000111700|Vega:OTTHUMG00000169011 +28299 IGKV1-5 HGNC:HGNC:5741|IMGT/GENE-DB:IGKV1-5 +28300 IGHV3OR16-16 HGNC:HGNC:5640|IMGT/GENE-DB:IGHV3/OR16-16 +28301 IGHV3OR16-15 HGNC:HGNC:5639|IMGT/GENE-DB:IGHV3/OR16-15 +28304 IGHV3OR16-12 HGNC:HGNC:5636|IMGT/GENE-DB:IGHV3/OR16-12 +28305 IGHV3OR16-11 HGNC:HGNC:5635|IMGT/GENE-DB:IGHV3/OR16-11 +28306 IGHV3OR16-10 HGNC:HGNC:5634|IMGT/GENE-DB:IGHV3/OR16-10 +28307 IGHV3OR16-9 HGNC:HGNC:5644|IMGT/GENE-DB:IGHV3/OR16-9 +28309 IGHV3OR16-7 HGNC:HGNC:5642|IMGT/GENE-DB:IGHV3/OR16-7 +28312 IGHV1OR16-4 HGNC:HGNC:5573|IMGT/GENE-DB:IGHV1/OR16-4 +28313 IGHV1OR16-3 HGNC:HGNC:5572|IMGT/GENE-DB:IGHV1/OR16-3 +28314 IGHV1OR16-2 HGNC:HGNC:5571|IMGT/GENE-DB:IGHV1/OR16-2 +28315 IGHV1OR16-1 HGNC:HGNC:5570|IMGT/GENE-DB:IGHV1/OR16-1 +28316 CDH20 MIM:605807|HGNC:HGNC:1760|Ensembl:ENSG00000101542|Vega:OTTHUMG00000132768 +28317 IGHV4OR15-8 HGNC:HGNC:5658|IMGT/GENE-DB:IGHV4/OR15-8 +28318 IGHV3OR15-7 HGNC:HGNC:5633|IMGT/GENE-DB:IGHV3/OR15-7 +28320 IGHV1OR15-6 HGNC:HGNC:5568|IMGT/GENE-DB:IGHV1/OR15-6 +28326 IGHD5OR15-5B HGNC:HGNC:5513|IMGT/GENE-DB:IGHD5/OR15-5b +28327 IGHD5OR15-5A HGNC:HGNC:5512|IMGT/GENE-DB:IGHD5/OR15-5a +28328 IGHD4OR15-4B HGNC:HGNC:5507|IMGT/GENE-DB:IGHD4/OR15-4b +28329 IGHD4OR15-4A HGNC:HGNC:5506|IMGT/GENE-DB:IGHD4/OR15-4a +28330 IGHD3OR15-3B HGNC:HGNC:5501|IMGT/GENE-DB:IGHD3/OR15-3b +28331 IGHD3OR15-3A HGNC:HGNC:5500|IMGT/GENE-DB:IGHD3/OR15-3a +28332 IGHD2OR15-2B HGNC:HGNC:5494|IMGT/GENE-DB:IGHD2/OR15-2b +28333 IGHD2OR15-2A HGNC:HGNC:5493|IMGT/GENE-DB:IGHD2/OR15-2a +28334 IGHD1OR15-1B HGNC:HGNC:5488|IMGT/GENE-DB:IGHD1/OR15-1b +28335 IGHD1OR15-1A HGNC:HGNC:5487|IMGT/GENE-DB:IGHD1/OR15-1a +28337 IGHVIV-44-1 HGNC:HGNC:5710|IMGT/GENE-DB:IGHV(IV)-44-1 +28338 IGHVIII-82 HGNC:HGNC:5709|IMGT/GENE-DB:IGHV(III)-82 +28339 IGHVIII-76-1 HGNC:HGNC:5708|IMGT/GENE-DB:IGHV(III)-76-1 +28340 IGHVIII-67-4 HGNC:HGNC:5707|IMGT/GENE-DB:IGHV(III)-67-4 +28341 IGHVIII-67-3 HGNC:HGNC:5706|IMGT/GENE-DB:IGHV(III)-67-3 +28342 IGHVIII-67-2 HGNC:HGNC:5705|IMGT/GENE-DB:IGHV(III)-67-2 +28343 IGHVIII-51-1 HGNC:HGNC:5704|IMGT/GENE-DB:IGHV(III)-51-1 +28344 IGHVIII-47-1 HGNC:HGNC:5701|IMGT/GENE-DB:IGHV(III)-47-1 +28345 IGHVIII-44 HGNC:HGNC:5700|IMGT/GENE-DB:IGHV(III)-44 +28346 IGHVIII-38-1 HGNC:HGNC:5699|IMGT/GENE-DB:IGHV(III)-38-1 +28347 IGHVIII-26-1 HGNC:HGNC:5698|IMGT/GENE-DB:IGHV(III)-26-1 +28348 IGHVIII-25-1 HGNC:HGNC:5697|IMGT/GENE-DB:IGHV(III)-25-1 +28349 IGHVIII-22-2 HGNC:HGNC:5696|IMGT/GENE-DB:IGHV(III)-22-2 +28350 IGHVIII-16-1 HGNC:HGNC:5694|IMGT/GENE-DB:IGHV(III)-16-1 +28351 IGHVIII-13-1 HGNC:HGNC:5693|IMGT/GENE-DB:IGHV(III)-13-1 +28352 IGHVIII-11-1 HGNC:HGNC:5692|IMGT/GENE-DB:IGHV(III)-11-1 +28353 IGHVIII-5-2 HGNC:HGNC:5703|IMGT/GENE-DB:IGHV(III)-5-2 +28354 IGHVIII-5-1 HGNC:HGNC:5702|IMGT/GENE-DB:IGHV(III)-5-1 +28355 IGHVIII-2-1 HGNC:HGNC:5695|IMGT/GENE-DB:IGHV(III)-2-1 +28356 IGHVII-78-1 HGNC:HGNC:5691|IMGT/GENE-DB:IGHV(II)-78-1 +28357 IGHVII-74-1 HGNC:HGNC:5690|IMGT/GENE-DB:IGHV(II)-74-1 +28358 IGHVII-67-1 HGNC:HGNC:5689|IMGT/GENE-DB:IGHV(II)-67-1 +28359 IGHVII-65-1 HGNC:HGNC:5688|IMGT/GENE-DB:IGHV(II)-65-1 +28360 IGHVII-62-1 HGNC:HGNC:5687|IMGT/GENE-DB:IGHV(II)-62-1 +28361 IGHVII-60-1 HGNC:HGNC:5686|IMGT/GENE-DB:IGHV(II)-60-1 +28362 IGHVII-53-1 HGNC:HGNC:5685|IMGT/GENE-DB:IGHV(II)-53-1 +28363 IGHVII-51-2 HGNC:HGNC:5684|IMGT/GENE-DB:IGHV(II)-51-2 +28364 IGHVII-49-1 HGNC:HGNC:5683|IMGT/GENE-DB:IGHV(II)-49-1 +28365 IGHVII-46-1 HGNC:HGNC:5682|IMGT/GENE-DB:IGHV(II)-46-1 +28366 IGHVII-44-2 HGNC:HGNC:5681|IMGT/GENE-DB:IGHV(II)-44-2 +28367 IGHVII-43-1 HGNC:HGNC:5680|IMGT/GENE-DB:IGHV(II)-43-1 +28368 IGHVII-40-1 HGNC:HGNC:5679|IMGT/GENE-DB:IGHV(II)-40-1 +28369 IGHVII-33-1 HGNC:HGNC:5678|IMGT/GENE-DB:IGHV(II)-33-1 +28370 IGHVII-31-1 HGNC:HGNC:5677|IMGT/GENE-DB:IGHV(II)-31-1 +28371 IGHVII-30-1 HGNC:HGNC:5676|IMGT/GENE-DB:IGHV(II)-30-1 +28372 IGHVII-28-1 HGNC:HGNC:5675|IMGT/GENE-DB:IGHV(II)-28-1 +28373 IGHVII-26-2 HGNC:HGNC:5674|IMGT/GENE-DB:IGHV(II)-26-2 +28374 IGHVII-22-1 HGNC:HGNC:5673|IMGT/GENE-DB:IGHV(II)-22-1 +28375 IGHVII-20-1 HGNC:HGNC:5672|IMGT/GENE-DB:IGHV(II)-20-1 +28376 IGHVII-15-1 HGNC:HGNC:5671|IMGT/GENE-DB:IGHV(II)-15-1 +28377 IGHVII-1-1 HGNC:HGNC:5670|IMGT/GENE-DB:IGHV(II)-1-1 +28378 IGHV7-81 HGNC:HGNC:5669|IMGT/GENE-DB:IGHV7-81 +28380 IGHV7-56 HGNC:HGNC:5667|IMGT/GENE-DB:IGHV7-56 +28381 IGHV7-40 HGNC:HGNC:5666|IMGT/GENE-DB:IGHV7-40 +28382 IGHV7-34-1 HGNC:HGNC:5664|IMGT/GENE-DB:IGHV7-34-1 +28383 IGHV7-27 HGNC:HGNC:5663|IMGT/GENE-DB:IGHV7-27 +28385 IGHV6-1 HGNC:HGNC:5662|IMGT/GENE-DB:IGHV6-1 +28386 IGHV5-10-1 HGNC:HGNC:5661|IMGT/GENE-DB:IGHV5-10-1 +28387 IGHV5-78 HGNC:HGNC:5660|IMGT/GENE-DB:IGHV5-78 +28388 IGHV5-51 HGNC:HGNC:5659|IMGT/GENE-DB:IGHV5-51 +28389 IGHV4-38-2 HGNC:HGNC:5657|IMGT/GENE-DB:IGHV4-38-2 +28390 IGHV4-80 HGNC:HGNC:5656|IMGT/GENE-DB:IGHV4-80 +28391 IGHV4-61 HGNC:HGNC:5655|IMGT/GENE-DB:IGHV4-61 +28392 IGHV4-59 HGNC:HGNC:5654|IMGT/GENE-DB:IGHV4-59 +28393 IGHV4-55 HGNC:HGNC:5653|IMGT/GENE-DB:IGHV4-55 +28394 IGHV4-39 HGNC:HGNC:5651|IMGT/GENE-DB:IGHV4-39 +28395 IGHV4-34 HGNC:HGNC:5650|IMGT/GENE-DB:IGHV4-34 +28396 IGHV4-31 HGNC:HGNC:5649|IMGT/GENE-DB:IGHV4-31 +28397 IGHV4-30-4 HGNC:HGNC:5648|IMGT/GENE-DB:IGHV4-30-4 +28398 IGHV4-30-2 HGNC:HGNC:5647|IMGT/GENE-DB:IGHV4-30-2 +28399 IGHV4-30-1 HGNC:HGNC:5646|IMGT/GENE-DB:IGHV4-30-1 +28400 IGHV4-28 HGNC:HGNC:5645|IMGT/GENE-DB:IGHV4-28 +28401 IGHV4-4 HGNC:HGNC:5652|IMGT/GENE-DB:IGHV4-4 +28402 IGHV3-69-1 HGNC:HGNC:5631|IMGT/GENE-DB:IGHV3-69-1 +28404 IGHV3-38-3 HGNC:HGNC:5629|IMGT/GENE-DB:IGHV3-38-3 +28405 IGHV3-79 HGNC:HGNC:5627|IMGT/GENE-DB:IGHV3-79 +28406 IGHV3-76 HGNC:HGNC:5626|IMGT/GENE-DB:IGHV3-76 +28407 IGHV3-75 HGNC:HGNC:5625|IMGT/GENE-DB:IGHV3-75 +28408 IGHV3-74 HGNC:HGNC:5624|IMGT/GENE-DB:IGHV3-74 +28409 IGHV3-73 HGNC:HGNC:5623|IMGT/GENE-DB:IGHV3-73 +28410 IGHV3-72 HGNC:HGNC:5622|IMGT/GENE-DB:IGHV3-72 +28411 IGHV3-71 HGNC:HGNC:5621|IMGT/GENE-DB:IGHV3-71 +28412 IGHV3-66 HGNC:HGNC:5619|IMGT/GENE-DB:IGHV3-66 +28413 IGHV3-65 HGNC:HGNC:5618|IMGT/GENE-DB:IGHV3-65 +28414 IGHV3-64 HGNC:HGNC:5617|IMGT/GENE-DB:IGHV3-64 +28415 IGHV3-63 HGNC:HGNC:5616|IMGT/GENE-DB:IGHV3-63 +28416 IGHV3-62 HGNC:HGNC:5615|IMGT/GENE-DB:IGHV3-62 +28417 IGHV3-60 HGNC:HGNC:5614|IMGT/GENE-DB:IGHV3-60 +28418 IGHV3-57 HGNC:HGNC:5612|IMGT/GENE-DB:IGHV3-57 +28419 IGHV3-54 HGNC:HGNC:5611|IMGT/GENE-DB:IGHV3-54 +28420 IGHV3-53 HGNC:HGNC:5610|IMGT/GENE-DB:IGHV3-53 +28421 IGHV3-52 HGNC:HGNC:5609|IMGT/GENE-DB:IGHV3-52 +28422 IGHV3-50 HGNC:HGNC:5608|IMGT/GENE-DB:IGHV3-50 +28423 IGHV3-49 HGNC:HGNC:5607|IMGT/GENE-DB:IGHV3-49 +28424 IGHV3-48 HGNC:HGNC:5606|IMGT/GENE-DB:IGHV3-48 +28425 IGHV3-47 HGNC:HGNC:5605|IMGT/GENE-DB:IGHV3-47 +28426 IGHV3-43 HGNC:HGNC:5604|IMGT/GENE-DB:IGHV3-43 +28427 IGHV3-42 HGNC:HGNC:5603|IMGT/GENE-DB:IGHV3-42 +28428 IGHV3-41 HGNC:HGNC:5602|IMGT/GENE-DB:IGHV3-41 +28429 IGHV3-38 HGNC:HGNC:5601|IMGT/GENE-DB:IGHV3-38 +28430 IGHV3-37 HGNC:HGNC:5600|IMGT/GENE-DB:IGHV3-37 +28431 IGHV3-36 HGNC:HGNC:5599|IMGT/GENE-DB:IGHV3-36 +28432 IGHV3-35 HGNC:HGNC:5598|IMGT/GENE-DB:IGHV3-35 +28433 IGHV3-33-2 HGNC:HGNC:5597|IMGT/GENE-DB:IGHV3-33-2 +28434 IGHV3-33 HGNC:HGNC:5596|IMGT/GENE-DB:IGHV3-33 +28435 IGHV3-32 HGNC:HGNC:5595|IMGT/GENE-DB:IGHV3-32 +28438 IGHV3-30-2 HGNC:HGNC:5592|IMGT/GENE-DB:IGHV3-30-2 +28439 IGHV3-30 HGNC:HGNC:5591|IMGT/GENE-DB:IGHV3-30 +28440 IGHV3-29 HGNC:HGNC:5590|IMGT/GENE-DB:IGHV3-29 +28441 IGHV3-25 HGNC:HGNC:5589|IMGT/GENE-DB:IGHV3-25 +28442 IGHV3-23 MIM:611939|HGNC:HGNC:5588|IMGT/GENE-DB:IGHV3-23 +28443 IGHV3-22 HGNC:HGNC:5587|IMGT/GENE-DB:IGHV3-22 +28444 IGHV3-21 HGNC:HGNC:5586|IMGT/GENE-DB:IGHV3-21 +28445 IGHV3-20 HGNC:HGNC:5585|IMGT/GENE-DB:IGHV3-20 +28446 IGHV3-19 HGNC:HGNC:5584|IMGT/GENE-DB:IGHV3-19 +28447 IGHV3-16 HGNC:HGNC:5583|IMGT/GENE-DB:IGHV3-16 +28448 IGHV3-15 HGNC:HGNC:5582|IMGT/GENE-DB:IGHV3-15 +28449 IGHV3-13 HGNC:HGNC:5581|IMGT/GENE-DB:IGHV3-13 +28450 IGHV3-11 HGNC:HGNC:5580|IMGT/GENE-DB:IGHV3-11 +28451 IGHV3-9 HGNC:HGNC:5628|IMGT/GENE-DB:IGHV3-9 +28452 IGHV3-7 HGNC:HGNC:5620|IMGT/GENE-DB:IGHV3-7 +28453 IGHV3-6 HGNC:HGNC:5613|IMGT/GENE-DB:IGHV3-6 +28454 IGHV2-70 HGNC:HGNC:5577|IMGT/GENE-DB:IGHV2-70 +28455 IGHV2-26 HGNC:HGNC:5575|IMGT/GENE-DB:IGHV2-26 +28456 IGHV2-10 HGNC:HGNC:5574|IMGT/GENE-DB:IGHV2-10 +28457 IGHV2-5 HGNC:HGNC:5576|IMGT/GENE-DB:IGHV2-5 +28458 IGHV1-69-2 HGNC:HGNC:5562|IMGT/GENE-DB:IGHV1-69-2 +28460 IGHV1-38-4 HGNC:HGNC:5560|IMGT/GENE-DB:IGHV1-38-4 +28461 IGHV1-69 HGNC:HGNC:5558|IMGT/GENE-DB:IGHV1-69 +28462 IGHV1-68 HGNC:HGNC:5557|IMGT/GENE-DB:IGHV1-68 +28463 IGHV1-67 HGNC:HGNC:5556|IMGT/GENE-DB:IGHV1-67 +28464 IGHV1-58 HGNC:HGNC:5555|IMGT/GENE-DB:IGHV1-58 +28465 IGHV1-46 HGNC:HGNC:5554|IMGT/GENE-DB:IGHV1-46 +28466 IGHV1-45 HGNC:HGNC:5553|IMGT/GENE-DB:IGHV1-45 +28467 IGHV1-24 HGNC:HGNC:5551|IMGT/GENE-DB:IGHV1-24 +28468 IGHV1-18 HGNC:HGNC:5549|IMGT/GENE-DB:IGHV1-18 +28469 IGHV1-17 HGNC:HGNC:5548|IMGT/GENE-DB:IGHV1-17 +28470 IGHV1-14 HGNC:HGNC:5547|IMGT/GENE-DB:IGHV1-14 +28471 IGHV1-12 HGNC:HGNC:5546|IMGT/GENE-DB:IGHV1-12 +28472 IGHV1-8 HGNC:HGNC:5559|IMGT/GENE-DB:IGHV1-8 +28473 IGHV1-3 HGNC:HGNC:5552|IMGT/GENE-DB:IGHV1-3 +28474 IGHV1-2 HGNC:HGNC:5550|IMGT/GENE-DB:IGHV1-2 +28475 IGHJ6 HGNC:HGNC:5540|IMGT/GENE-DB:IGHJ6 +28476 IGHJ5 HGNC:HGNC:5539|IMGT/GENE-DB:IGHJ5 +28477 IGHJ4 HGNC:HGNC:5538|IMGT/GENE-DB:IGHJ4 +28478 IGHJ3P HGNC:HGNC:5537|IMGT/GENE-DB:IGHJ3P +28479 IGHJ3 HGNC:HGNC:5536|IMGT/GENE-DB:IGHJ3 +28480 IGHJ2P HGNC:HGNC:5535|IMGT/GENE-DB:IGHJ2P +28481 IGHJ2 HGNC:HGNC:5534|IMGT/GENE-DB:IGHJ2 +28482 IGHJ1P HGNC:HGNC:5533|IMGT/GENE-DB:IGHJ1P +28483 IGHJ1 HGNC:HGNC:5532|IMGT/GENE-DB:IGHJ1 +28484 IGHD7-27 HGNC:HGNC:5518|IMGT/GENE-DB:IGHD7-27 +28485 IGHD6-25 HGNC:HGNC:5516|IMGT/GENE-DB:IGHD6-25 +28486 IGHD6-19 HGNC:HGNC:5515|IMGT/GENE-DB:IGHD6-19 +28487 IGHD6-13 HGNC:HGNC:5514|IMGT/GENE-DB:IGHD6-13 +28488 IGHD6-6 HGNC:HGNC:5517|IMGT/GENE-DB:IGHD6-6 +28489 IGHD5-24 HGNC:HGNC:5510|IMGT/GENE-DB:IGHD5-24 +28490 IGHD5-18 HGNC:HGNC:5509|IMGT/GENE-DB:IGHD5-18 +28491 IGHD5-12 HGNC:HGNC:5508|IMGT/GENE-DB:IGHD5-12 +28492 IGHD5-5 HGNC:HGNC:5511|IMGT/GENE-DB:IGHD5-5 +28493 IGHD4-23 HGNC:HGNC:5504|IMGT/GENE-DB:IGHD4-23 +28494 IGHD4-17 HGNC:HGNC:5503|IMGT/GENE-DB:IGHD4-17 +28495 IGHD4-11 HGNC:HGNC:5502|IMGT/GENE-DB:IGHD4-11 +28496 IGHD4-4 HGNC:HGNC:5505|IMGT/GENE-DB:IGHD4-4 +28497 IGHD3-22 HGNC:HGNC:5497|IMGT/GENE-DB:IGHD3-22 +28498 IGHD3-16 HGNC:HGNC:5496|IMGT/GENE-DB:IGHD3-16 +28499 IGHD3-10 HGNC:HGNC:5495|IMGT/GENE-DB:IGHD3-10 +28500 IGHD3-9 HGNC:HGNC:5499|IMGT/GENE-DB:IGHD3-9 +28501 IGHD3-3 MIM:611937|HGNC:HGNC:5498|IMGT/GENE-DB:IGHD3-3 +28502 IGHD2-21 HGNC:HGNC:5491|IMGT/GENE-DB:IGHD2-21 +28503 IGHD2-15 HGNC:HGNC:5489|IMGT/GENE-DB:IGHD2-15 +28504 IGHD2-8 HGNC:HGNC:5492|IMGT/GENE-DB:IGHD2-8 +28505 IGHD2-2 HGNC:HGNC:5490|IMGT/GENE-DB:IGHD2-2 +28506 IGHD1-26 HGNC:HGNC:5485|IMGT/GENE-DB:IGHD1-26 +28507 IGHD1-20 HGNC:HGNC:5484|IMGT/GENE-DB:IGHD1-20 +28508 IGHD1-14 HGNC:HGNC:5483|IMGT/GENE-DB:IGHD1-14 +28509 IGHD1-7 HGNC:HGNC:5486|IMGT/GENE-DB:IGHD1-7 +28510 IGHD1-1 HGNC:HGNC:5482|IMGT/GENE-DB:IGHD1-1 +28511 NKIRAS2 MIM:604497|HGNC:HGNC:17898|Ensembl:ENSG00000168256|Vega:OTTHUMG00000133503 +28512 NKIRAS1 MIM:604496|HGNC:HGNC:17899|Ensembl:ENSG00000197885|Vega:OTTHUMG00000155605 +28513 CDH19 MIM:603016|HGNC:HGNC:1758|Ensembl:ENSG00000071991|Vega:OTTHUMG00000132802 +28514 DLL1 MIM:606582|HGNC:HGNC:2908|Ensembl:ENSG00000198719|Vega:OTTHUMG00000016078 +28515 HYPLIP2 MIM:604499 +28516 TRDV3 HGNC:HGNC:12264|IMGT/GENE-DB:TRDV3 +28517 TRDV2 HGNC:HGNC:12263|IMGT/GENE-DB:TRDV2 +28518 TRDV1 HGNC:HGNC:12262|IMGT/GENE-DB:TRDV1 +28519 TRDJ4 HGNC:HGNC:12260|IMGT/GENE-DB:TRDJ4 +28520 TRDJ3 HGNC:HGNC:12259|IMGT/GENE-DB:TRDJ3 +28521 TRDJ2 HGNC:HGNC:12258|IMGT/GENE-DB:TRDJ2 +28522 TRDJ1 HGNC:HGNC:12257|IMGT/GENE-DB:TRDJ1 +28523 TRDD3 HGNC:HGNC:12256|IMGT/GENE-DB:TRDD3 +28524 TRDD2 HGNC:HGNC:12255|IMGT/GENE-DB:TRDD2 +28525 TRDD1 HGNC:HGNC:12254|IMGT/GENE-DB:TRDD1 +28526 TRDC MIM:186810|HGNC:HGNC:12253|IMGT/GENE-DB:TRDC +28552 TRBV23OR9-2 HGNC:HGNC:12202|IMGT/GENE-DB:TRBV23/OR9-2 +28555 TRBVB HGNC:HGNC:12248|IMGT/GENE-DB:TRBVB +28556 TRBVA HGNC:HGNC:12247|IMGT/GENE-DB:TRBVA +28557 TRBV30 HGNC:HGNC:12214|IMGT/GENE-DB:TRBV30 +28558 TRBV29-1 HGNC:HGNC:12210|IMGT/GENE-DB:TRBV29-1 +28559 TRBV28 HGNC:HGNC:12209|IMGT/GENE-DB:TRBV28 +28560 TRBV27 HGNC:HGNC:12208|IMGT/GENE-DB:TRBV27 +28561 TRBV26 HGNC:HGNC:12207|IMGT/GENE-DB:TRBV26 +28562 TRBV25-1 HGNC:HGNC:12205|IMGT/GENE-DB:TRBV25-1 +28563 TRBV24-1 HGNC:HGNC:12203|IMGT/GENE-DB:TRBV24-1 +28564 TRBV23-1 HGNC:HGNC:12201|IMGT/GENE-DB:TRBV23-1 +28565 TRBV22-1 HGNC:HGNC:12200|IMGT/GENE-DB:TRBV22-1 +28566 TRBV21-1 HGNC:HGNC:12198|IMGT/GENE-DB:TRBV21-1 +28567 TRBV20-1 HGNC:HGNC:12196|IMGT/GENE-DB:TRBV20-1 +28568 TRBV19 HGNC:HGNC:12194|IMGT/GENE-DB:TRBV19 +28569 TRBV18 HGNC:HGNC:12193|IMGT/GENE-DB:TRBV18 +28570 TRBV17 HGNC:HGNC:12192|IMGT/GENE-DB:TRBV17 +28571 TRBV16 HGNC:HGNC:12191|IMGT/GENE-DB:TRBV16 +28572 TRBV15 HGNC:HGNC:12190|IMGT/GENE-DB:TRBV15 +28573 TRBV14 HGNC:HGNC:12189|IMGT/GENE-DB:TRBV14 +28574 TRBV13 HGNC:HGNC:12188|IMGT/GENE-DB:TRBV13 +28575 TRBV12-5 HGNC:HGNC:12187|IMGT/GENE-DB:TRBV12-5 +28576 TRBV12-4 HGNC:HGNC:12186|IMGT/GENE-DB:TRBV12-4 +28577 TRBV12-3 HGNC:HGNC:12185|IMGT/GENE-DB:TRBV12-3 +28578 TRBV12-2 HGNC:HGNC:12184|IMGT/GENE-DB:TRBV12-2 +28579 TRBV12-1 HGNC:HGNC:12183|IMGT/GENE-DB:TRBV12-1 +28580 TRBV11-3 HGNC:HGNC:12182|IMGT/GENE-DB:TRBV11-3 +28581 TRBV11-2 HGNC:HGNC:12181|IMGT/GENE-DB:TRBV11-2 +28582 TRBV11-1 HGNC:HGNC:12180|IMGT/GENE-DB:TRBV11-1 +28583 TRBV10-3 HGNC:HGNC:12179|IMGT/GENE-DB:TRBV10-3 +28584 TRBV10-2 HGNC:HGNC:12178|IMGT/GENE-DB:TRBV10-2 +28585 TRBV10-1 HGNC:HGNC:12177|IMGT/GENE-DB:TRBV10-1 +28586 TRBV9 HGNC:HGNC:12246|IMGT/GENE-DB:TRBV9 +28587 TRBV8-2 HGNC:HGNC:12245|IMGT/GENE-DB:TRBV8-2 +28588 TRBV8-1 HGNC:HGNC:12244|IMGT/GENE-DB:TRBV8-1 +28589 TRBV7-9 HGNC:HGNC:12243|IMGT/GENE-DB:TRBV7-9 +28590 TRBV7-8 HGNC:HGNC:12242|IMGT/GENE-DB:TRBV7-8 +28591 TRBV7-7 HGNC:HGNC:12241|IMGT/GENE-DB:TRBV7-7 +28592 TRBV7-6 HGNC:HGNC:12240|IMGT/GENE-DB:TRBV7-6 +28593 TRBV7-5 HGNC:HGNC:12239|IMGT/GENE-DB:TRBV7-5 +28594 TRBV7-4 HGNC:HGNC:12238|IMGT/GENE-DB:TRBV7-4 +28595 TRBV7-3 HGNC:HGNC:12237|IMGT/GENE-DB:TRBV7-3 +28596 TRBV7-2 HGNC:HGNC:12236|IMGT/GENE-DB:TRBV7-2 +28597 TRBV7-1 HGNC:HGNC:12235|IMGT/GENE-DB:TRBV7-1 +28598 TRBV6-9 HGNC:HGNC:12234|IMGT/GENE-DB:TRBV6-9 +28599 TRBV6-8 HGNC:HGNC:12233|IMGT/GENE-DB:TRBV6-8 +28600 TRBV6-7 HGNC:HGNC:12232|IMGT/GENE-DB:TRBV6-7 +28601 TRBV6-6 HGNC:HGNC:12231|IMGT/GENE-DB:TRBV6-6 +28602 TRBV6-5 HGNC:HGNC:12230|IMGT/GENE-DB:TRBV6-5 +28603 TRBV6-4 HGNC:HGNC:12229|IMGT/GENE-DB:TRBV6-4 +28604 TRBV6-3 HGNC:HGNC:12228|IMGT/GENE-DB:TRBV6-3 +28605 TRBV6-2 HGNC:HGNC:12227|IMGT/GENE-DB:TRBV6-2 +28606 TRBV6-1 HGNC:HGNC:12226|IMGT/GENE-DB:TRBV6-1 +28607 TRBV5-8 HGNC:HGNC:12225|IMGT/GENE-DB:TRBV5-8 +28608 TRBV5-7 HGNC:HGNC:12224|IMGT/GENE-DB:TRBV5-7 +28609 TRBV5-6 HGNC:HGNC:12223|IMGT/GENE-DB:TRBV5-6 +28610 TRBV5-5 HGNC:HGNC:12222|IMGT/GENE-DB:TRBV5-5 +28611 TRBV5-4 HGNC:HGNC:12221|IMGT/GENE-DB:TRBV5-4 +28612 TRBV5-3 HGNC:HGNC:12220|IMGT/GENE-DB:TRBV5-3 +28613 TRBV5-2 HGNC:HGNC:12219|IMGT/GENE-DB:TRBV5-2 +28614 TRBV5-1 HGNC:HGNC:12218|IMGT/GENE-DB:TRBV5-1 +28615 TRBV4-3 HGNC:HGNC:12217|IMGT/GENE-DB:TRBV4-3 +28616 TRBV4-2 HGNC:HGNC:12216|IMGT/GENE-DB:TRBV4-2 +28617 TRBV4-1 HGNC:HGNC:12215|IMGT/GENE-DB:TRBV4-1 +28618 TRBV3-2 HGNC:HGNC:12213|IMGT/GENE-DB:TRBV3-2 +28619 TRBV3-1 HGNC:HGNC:12212|IMGT/GENE-DB:TRBV3-1 +28620 TRBV2 HGNC:HGNC:12195|IMGT/GENE-DB:TRBV2 +28621 TRBV1 HGNC:HGNC:12176|IMGT/GENE-DB:TRBV1 +28622 TRBJ2-7 HGNC:HGNC:12175|IMGT/GENE-DB:TRBJ2-7 +28623 TRBJ2-6 HGNC:HGNC:12174|IMGT/GENE-DB:TRBJ2-6 +28624 TRBJ2-5 HGNC:HGNC:12173|IMGT/GENE-DB:TRBJ2-5 +28625 TRBJ2-4 HGNC:HGNC:12172|IMGT/GENE-DB:TRBJ2-4 +28626 TRBJ2-3 HGNC:HGNC:12171|IMGT/GENE-DB:TRBJ2-3 +28627 TRBJ2-2P HGNC:HGNC:12170|IMGT/GENE-DB:TRBJ2-2P +28628 TRBJ2-2 HGNC:HGNC:12169|IMGT/GENE-DB:TRBJ2-2 +28629 TRBJ2-1 HGNC:HGNC:12168|IMGT/GENE-DB:TRBJ2-1 +28630 TRBJ1-6 HGNC:HGNC:12167|IMGT/GENE-DB:TRBJ1-6 +28631 TRBJ1-5 HGNC:HGNC:12166|IMGT/GENE-DB:TRBJ1-5 +28632 TRBJ1-4 HGNC:HGNC:12165|IMGT/GENE-DB:TRBJ1-4 +28633 TRBJ1-3 HGNC:HGNC:12164|IMGT/GENE-DB:TRBJ1-3 +28634 TRBJ1-2 HGNC:HGNC:12163|IMGT/GENE-DB:TRBJ1-2 +28635 TRBJ1-1 HGNC:HGNC:12162|IMGT/GENE-DB:TRBJ1-1 +28636 TRBD2 MIM:615448|HGNC:HGNC:12159|IMGT/GENE-DB:TRBD2 +28637 TRBD1 MIM:615447|HGNC:HGNC:12158|IMGT/GENE-DB:TRBD1 +28638 TRBC2 MIM:615445|HGNC:HGNC:12157|IMGT/GENE-DB:TRBC2 +28639 TRBC1 MIM:186930|HGNC:HGNC:12156|IMGT/GENE-DB:TRBC1 +28640 TRAV41 HGNC:HGNC:12142|IMGT/GENE-DB:TRAV41 +28641 TRAV40 HGNC:HGNC:12141|IMGT/GENE-DB:TRAV40 +28642 TRAV39 HGNC:HGNC:12139|IMGT/GENE-DB:TRAV39 +28643 TRAV38-2DV8 HGNC:HGNC:12138|IMGT/GENE-DB:TRAV38-2/DV8 +28644 TRAV38-1 HGNC:HGNC:12137|IMGT/GENE-DB:TRAV38-1 +28645 TRAV37 HGNC:HGNC:12136|IMGT/GENE-DB:TRAV37 +28646 TRAV36DV7 HGNC:HGNC:12135|IMGT/GENE-DB:TRAV36/DV7 +28647 TRAV35 HGNC:HGNC:12134|IMGT/GENE-DB:TRAV35 +28648 TRAV34 HGNC:HGNC:12133|IMGT/GENE-DB:TRAV34 +28649 TRAV33 HGNC:HGNC:12132|IMGT/GENE-DB:TRAV33 +28650 TRAV32 HGNC:HGNC:12131|IMGT/GENE-DB:TRAV32 +28651 TRAV31 HGNC:HGNC:12130|IMGT/GENE-DB:TRAV31 +28652 TRAV30 HGNC:HGNC:12129|IMGT/GENE-DB:TRAV30 +28653 TRAV29DV5 HGNC:HGNC:12127|IMGT/GENE-DB:TRAV29/DV5 +28654 TRAV28 HGNC:HGNC:12126|IMGT/GENE-DB:TRAV28 +28655 TRAV27 HGNC:HGNC:12125|IMGT/GENE-DB:TRAV27 +28656 TRAV26-2 HGNC:HGNC:12124|IMGT/GENE-DB:TRAV26-2 +28657 TRAV26-1 HGNC:HGNC:12123|IMGT/GENE-DB:TRAV26-1 +28658 TRAV25 HGNC:HGNC:12122|IMGT/GENE-DB:TRAV25 +28659 TRAV24 HGNC:HGNC:12121|IMGT/GENE-DB:TRAV24 +28660 TRAV23DV6 HGNC:HGNC:12120|IMGT/GENE-DB:TRAV23/DV6 +28661 TRAV22 HGNC:HGNC:12119|IMGT/GENE-DB:TRAV22 +28662 TRAV21 HGNC:HGNC:12118|IMGT/GENE-DB:TRAV21 +28663 TRAV20 HGNC:HGNC:12117|IMGT/GENE-DB:TRAV20 +28664 TRAV19 HGNC:HGNC:12115|IMGT/GENE-DB:TRAV19 +28665 TRAV18 HGNC:HGNC:12114|IMGT/GENE-DB:TRAV18 +28666 TRAV17 HGNC:HGNC:12113|IMGT/GENE-DB:TRAV17 +28667 TRAV16 HGNC:HGNC:12112|IMGT/GENE-DB:TRAV16 +28668 TRAV15 HGNC:HGNC:12111|IMGT/GENE-DB:TRAV15 +28669 TRAV14DV4 HGNC:HGNC:12110|IMGT/GENE-DB:TRAV14/DV4 +28670 TRAV13-2 HGNC:HGNC:12109|IMGT/GENE-DB:TRAV13-2 +28671 TRAV13-1 HGNC:HGNC:12108|IMGT/GENE-DB:TRAV13-1 +28672 TRAV12-3 HGNC:HGNC:12107|IMGT/GENE-DB:TRAV12-3 +28673 TRAV12-2 HGNC:HGNC:12106|IMGT/GENE-DB:TRAV12-2 +28674 TRAV12-1 HGNC:HGNC:12105|IMGT/GENE-DB:TRAV12-1 +28675 TRAV11 HGNC:HGNC:12104|IMGT/GENE-DB:TRAV11 +28676 TRAV10 HGNC:HGNC:12103|IMGT/GENE-DB:TRAV10 +28677 TRAV9-2 HGNC:HGNC:12154|IMGT/GENE-DB:TRAV9-2 +28678 TRAV9-1 HGNC:HGNC:12153|IMGT/GENE-DB:TRAV9-1 +28679 TRAV8-7 HGNC:HGNC:12152|IMGT/GENE-DB:TRAV8-7 +28680 TRAV8-6 HGNC:HGNC:12151|IMGT/GENE-DB:TRAV8-6 +28681 TRAV8-5 HGNC:HGNC:12150|IMGT/GENE-DB:TRAV8-5 +28682 TRAV8-4 HGNC:HGNC:12149|IMGT/GENE-DB:TRAV8-4 +28683 TRAV8-3 HGNC:HGNC:12148|IMGT/GENE-DB:TRAV8-3 +28684 TRAV8-2 HGNC:HGNC:12147|IMGT/GENE-DB:TRAV8-2 +28685 TRAV8-1 HGNC:HGNC:12146|IMGT/GENE-DB:TRAV8-1 +28686 TRAV7 HGNC:HGNC:12145|IMGT/GENE-DB:TRAV7 +28688 TRAV5 HGNC:HGNC:12143|IMGT/GENE-DB:TRAV5 +28689 TRAV4 HGNC:HGNC:12140|IMGT/GENE-DB:TRAV4 +28690 TRAV3 HGNC:HGNC:12128|IMGT/GENE-DB:TRAV3 +28691 TRAV2 HGNC:HGNC:12116|IMGT/GENE-DB:TRAV2 +28692 TRAV1-2 HGNC:HGNC:12102|IMGT/GENE-DB:TRAV1-2 +28693 TRAV1-1 HGNC:HGNC:12101|IMGT/GENE-DB:TRAV1-1 +28694 TRAJ61 HGNC:HGNC:12094|IMGT/GENE-DB:TRAJ61 +28695 TRAJ60 HGNC:HGNC:12093|IMGT/GENE-DB:TRAJ60 +28696 TRAJ59 HGNC:HGNC:12091|IMGT/GENE-DB:TRAJ59 +28697 TRAJ58 HGNC:HGNC:12090|IMGT/GENE-DB:TRAJ58 +28698 TRAJ57 HGNC:HGNC:12089|IMGT/GENE-DB:TRAJ57 +28699 TRAJ56 HGNC:HGNC:12088|IMGT/GENE-DB:TRAJ56 +28700 TRAJ55 HGNC:HGNC:12087|IMGT/GENE-DB:TRAJ55 +28701 TRAJ54 HGNC:HGNC:12086|IMGT/GENE-DB:TRAJ54 +28702 TRAJ53 HGNC:HGNC:12085|IMGT/GENE-DB:TRAJ53 +28703 TRAJ52 HGNC:HGNC:12084|IMGT/GENE-DB:TRAJ52 +28704 TRAJ51 HGNC:HGNC:12083|IMGT/GENE-DB:TRAJ51 +28705 TRAJ50 HGNC:HGNC:12082|IMGT/GENE-DB:TRAJ50 +28706 TRAJ49 HGNC:HGNC:12080|IMGT/GENE-DB:TRAJ49 +28707 TRAJ48 HGNC:HGNC:12079|IMGT/GENE-DB:TRAJ48 +28708 TRAJ47 HGNC:HGNC:12078|IMGT/GENE-DB:TRAJ47 +28709 TRAJ46 HGNC:HGNC:12077|IMGT/GENE-DB:TRAJ46 +28710 TRAJ45 HGNC:HGNC:12076|IMGT/GENE-DB:TRAJ45 +28711 TRAJ44 HGNC:HGNC:12075|IMGT/GENE-DB:TRAJ44 +28712 TRAJ43 HGNC:HGNC:12074|IMGT/GENE-DB:TRAJ43 +28713 TRAJ42 HGNC:HGNC:12073|IMGT/GENE-DB:TRAJ42 +28714 TRAJ41 HGNC:HGNC:12072|IMGT/GENE-DB:TRAJ41 +28715 TRAJ40 HGNC:HGNC:12071|IMGT/GENE-DB:TRAJ40 +28716 TRAJ39 HGNC:HGNC:12069|IMGT/GENE-DB:TRAJ39 +28717 TRAJ38 HGNC:HGNC:12068|IMGT/GENE-DB:TRAJ38 +28718 TRAJ37 HGNC:HGNC:12067|IMGT/GENE-DB:TRAJ37 +28719 TRAJ36 HGNC:HGNC:12066|IMGT/GENE-DB:TRAJ36 +28720 TRAJ35 HGNC:HGNC:12065|IMGT/GENE-DB:TRAJ35 +28721 TRAJ34 HGNC:HGNC:12064|IMGT/GENE-DB:TRAJ34 +28722 TRAJ33 HGNC:HGNC:12063|IMGT/GENE-DB:TRAJ33 +28723 TRAJ32 HGNC:HGNC:12062|IMGT/GENE-DB:TRAJ32 +28724 TRAJ31 HGNC:HGNC:12061|IMGT/GENE-DB:TRAJ31 +28725 TRAJ30 HGNC:HGNC:12060|IMGT/GENE-DB:TRAJ30 +28726 TRAJ29 HGNC:HGNC:12058|IMGT/GENE-DB:TRAJ29 +28727 TRAJ28 HGNC:HGNC:12057|IMGT/GENE-DB:TRAJ28 +28728 TRAJ27 HGNC:HGNC:12056|IMGT/GENE-DB:TRAJ27 +28729 TRAJ26 HGNC:HGNC:12055|IMGT/GENE-DB:TRAJ26 +28730 TRAJ25 HGNC:HGNC:12054|IMGT/GENE-DB:TRAJ25 +28731 TRAJ24 HGNC:HGNC:12053|IMGT/GENE-DB:TRAJ24 +28732 TRAJ23 HGNC:HGNC:12052|IMGT/GENE-DB:TRAJ23 +28733 TRAJ22 HGNC:HGNC:12051|IMGT/GENE-DB:TRAJ22 +28734 TRAJ21 HGNC:HGNC:12050|IMGT/GENE-DB:TRAJ21 +28735 TRAJ20 HGNC:HGNC:12049|IMGT/GENE-DB:TRAJ20 +28736 TRAJ19 HGNC:HGNC:12047|IMGT/GENE-DB:TRAJ19 +28737 TRAJ18 HGNC:HGNC:12046|IMGT/GENE-DB:TRAJ18 +28738 TRAJ17 HGNC:HGNC:12045|IMGT/GENE-DB:TRAJ17 +28739 TRAJ16 HGNC:HGNC:12044|IMGT/GENE-DB:TRAJ16 +28740 TRAJ15 HGNC:HGNC:12043|IMGT/GENE-DB:TRAJ15 +28741 TRAJ14 HGNC:HGNC:12042|IMGT/GENE-DB:TRAJ14 +28742 TRAJ13 HGNC:HGNC:12041|IMGT/GENE-DB:TRAJ13 +28743 TRAJ12 HGNC:HGNC:12040|IMGT/GENE-DB:TRAJ12 +28744 TRAJ11 HGNC:HGNC:12039|IMGT/GENE-DB:TRAJ11 +28745 TRAJ10 HGNC:HGNC:12038|IMGT/GENE-DB:TRAJ10 +28746 TRAJ9 HGNC:HGNC:12097|IMGT/GENE-DB:TRAJ9 +28747 TRAJ8 HGNC:HGNC:12096|IMGT/GENE-DB:TRAJ8 +28748 TRAJ7 HGNC:HGNC:12095|IMGT/GENE-DB:TRAJ7 +28749 TRAJ6 HGNC:HGNC:12092|IMGT/GENE-DB:TRAJ6 +28750 TRAJ5 HGNC:HGNC:12081|IMGT/GENE-DB:TRAJ5 +28751 TRAJ4 HGNC:HGNC:12070|IMGT/GENE-DB:TRAJ4 +28752 TRAJ3 HGNC:HGNC:12059|IMGT/GENE-DB:TRAJ3 +28753 TRAJ2 HGNC:HGNC:12048|IMGT/GENE-DB:TRAJ2 +28754 TRAJ1 HGNC:HGNC:12037|IMGT/GENE-DB:TRAJ1 +28755 TRAC MIM:186880|HGNC:HGNC:12029|IMGT/GENE-DB:TRAC +28756 IGLV8OR8-1 HGNC:HGNC:5932|IMGT/GENE-DB:IGLV8/OR8-1 +28757 IGLVV-66 HGNC:HGNC:5946|IMGT/GENE-DB:IGLV(V)-66 +28758 IGLVV-58 HGNC:HGNC:5945|IMGT/GENE-DB:IGLV(V)-58 +28759 IGLVIV-65 HGNC:HGNC:5944|IMGT/GENE-DB:IGLV(IV)-65 +28760 IGLVIV-64 HGNC:HGNC:5943|IMGT/GENE-DB:IGLV(IV)-64 +28761 IGLVIV-59 HGNC:HGNC:5942|IMGT/GENE-DB:IGLV(IV)-59 +28762 IGLVIV-53 HGNC:HGNC:5941|IMGT/GENE-DB:IGLV(IV)-53 +28763 IGLVI-70 HGNC:HGNC:5940|IMGT/GENE-DB:IGLV(I)-70 +28764 IGLVI-68 HGNC:HGNC:5939|IMGT/GENE-DB:IGLV(I)-68 +28765 IGLVI-63 HGNC:HGNC:5938|IMGT/GENE-DB:IGLV(I)-63 +28766 IGLVI-56 HGNC:HGNC:5937|IMGT/GENE-DB:IGLV(I)-56 +28767 IGLVI-42 HGNC:HGNC:5936|IMGT/GENE-DB:IGLV(I)-42 +28768 IGLVI-38 HGNC:HGNC:5935|IMGT/GENE-DB:IGLV(I)-38 +28769 IGLVI-20 HGNC:HGNC:5934|IMGT/GENE-DB:IGLV(I)-20 +28770 IGLV11-55 HGNC:HGNC:5886|IMGT/GENE-DB:IGLV11-55 +28771 IGLV10-67 HGNC:HGNC:5885|IMGT/GENE-DB:IGLV10-67 +28772 IGLV10-54 HGNC:HGNC:5884|IMGT/GENE-DB:IGLV10-54 +28773 IGLV9-49 HGNC:HGNC:5933|IMGT/GENE-DB:IGLV9-49 +28774 IGLV8-61 HGNC:HGNC:5931|IMGT/GENE-DB:IGLV8-61 +28775 IGLV7-46 HGNC:HGNC:5930|IMGT/GENE-DB:IGLV7-46 +28776 IGLV7-43 HGNC:HGNC:5929|IMGT/GENE-DB:IGLV7-43 +28777 IGLV7-35 HGNC:HGNC:5928|IMGT/GENE-DB:IGLV7-35 +28778 IGLV6-57 HGNC:HGNC:5927|IMGT/GENE-DB:IGLV6-57 +28779 IGLV5-52 HGNC:HGNC:5926|IMGT/GENE-DB:IGLV5-52 +28780 IGLV5-48 HGNC:HGNC:5925|IMGT/GENE-DB:IGLV5-48 +28781 IGLV5-45 HGNC:HGNC:5924|IMGT/GENE-DB:IGLV5-45 +28782 IGLV5-39 HGNC:HGNC:5923|IMGT/GENE-DB:IGLV5-39 +28783 IGLV5-37 HGNC:HGNC:5922|IMGT/GENE-DB:IGLV5-37 +28784 IGLV4-69 HGNC:HGNC:5921|IMGT/GENE-DB:IGLV4-69 +28785 IGLV4-60 HGNC:HGNC:5920|IMGT/GENE-DB:IGLV4-60 +28786 IGLV4-3 HGNC:HGNC:5919|IMGT/GENE-DB:IGLV4-3 +28787 IGLV3-32 HGNC:HGNC:5914|IMGT/GENE-DB:IGLV3-32 +28788 IGLV3-31 HGNC:HGNC:5913|IMGT/GENE-DB:IGLV3-31 +28789 IGLV3-30 HGNC:HGNC:5912|IMGT/GENE-DB:IGLV3-30 +28790 IGLV3-29 HGNC:HGNC:5911|IMGT/GENE-DB:IGLV3-29 +28791 IGLV3-27 HGNC:HGNC:5910|IMGT/GENE-DB:IGLV3-27 +28792 IGLV3-26 HGNC:HGNC:5909|IMGT/GENE-DB:IGLV3-26 +28793 IGLV3-25 HGNC:HGNC:5908|IMGT/GENE-DB:IGLV3-25 +28794 IGLV3-24 HGNC:HGNC:5907|IMGT/GENE-DB:IGLV3-24 +28795 IGLV3-22 HGNC:HGNC:5906|IMGT/GENE-DB:IGLV3-22 +28796 IGLV3-21 HGNC:HGNC:5905|IMGT/GENE-DB:IGLV3-21 +28797 IGLV3-19 HGNC:HGNC:5903|IMGT/GENE-DB:IGLV3-19 +28798 IGLV3-17 HGNC:HGNC:5902|IMGT/GENE-DB:IGLV3-17 +28799 IGLV3-16 HGNC:HGNC:5901|IMGT/GENE-DB:IGLV3-16 +28800 IGLV3-15 HGNC:HGNC:5900|IMGT/GENE-DB:IGLV3-15 +28801 IGLV3-13 HGNC:HGNC:5899|IMGT/GENE-DB:IGLV3-13 +28802 IGLV3-12 HGNC:HGNC:5898|IMGT/GENE-DB:IGLV3-12 +28803 IGLV3-10 HGNC:HGNC:5897|IMGT/GENE-DB:IGLV3-10 +28804 IGLV3-9 HGNC:HGNC:5918|IMGT/GENE-DB:IGLV3-9 +28805 IGLV3-7 HGNC:HGNC:5917|IMGT/GENE-DB:IGLV3-7 +28806 IGLV3-6 HGNC:HGNC:5916|IMGT/GENE-DB:IGLV3-6 +28807 IGLV3-4 HGNC:HGNC:5915|IMGT/GENE-DB:IGLV3-4 +28808 IGLV3-2 HGNC:HGNC:5904|IMGT/GENE-DB:IGLV3-2 +28809 IGLV3-1 HGNC:HGNC:5896|IMGT/GENE-DB:IGLV3-1 +28810 IGLV2-34 HGNC:HGNC:5893|IMGT/GENE-DB:IGLV2-34 +28811 IGLV2-33 HGNC:HGNC:5892|IMGT/GENE-DB:IGLV2-33 +28812 IGLV2-28 HGNC:HGNC:5891|IMGT/GENE-DB:IGLV2-28 +28813 IGLV2-23 HGNC:HGNC:5890|IMGT/GENE-DB:IGLV2-23 +28814 IGLV2-18 HGNC:HGNC:5889|IMGT/GENE-DB:IGLV2-18 +28815 IGLV2-14 HGNC:HGNC:5888|IMGT/GENE-DB:IGLV2-14 +28816 IGLV2-11 HGNC:HGNC:5887|IMGT/GENE-DB:IGLV2-11 +28817 IGLV2-8 HGNC:HGNC:5895|IMGT/GENE-DB:IGLV2-8 +28818 IGLV2-5 HGNC:HGNC:5894|IMGT/GENE-DB:IGLV2-5 +28819 IGLV1-62 HGNC:HGNC:5883|IMGT/GENE-DB:IGLV1-62 +28820 IGLV1-51 HGNC:HGNC:5882|IMGT/GENE-DB:IGLV1-51 +28821 IGLV1-50 HGNC:HGNC:5881|IMGT/GENE-DB:IGLV1-50 +28822 IGLV1-47 HGNC:HGNC:5880|IMGT/GENE-DB:IGLV1-47 +28823 IGLV1-44 HGNC:HGNC:5879|IMGT/GENE-DB:IGLV1-44 +28824 IGLV1-41 HGNC:HGNC:5878|IMGT/GENE-DB:IGLV1-41 +28825 IGLV1-40 HGNC:HGNC:5877|IMGT/GENE-DB:IGLV1-40 +28826 IGLV1-36 HGNC:HGNC:5876|IMGT/GENE-DB:IGLV1-36 +28827 IGLJ7 HGNC:HGNC:5869|IMGT/GENE-DB:IGLJ7 +28828 IGLJ6 HGNC:HGNC:5868|IMGT/GENE-DB:IGLJ6 +28829 IGLJ5 HGNC:HGNC:5867|IMGT/GENE-DB:IGLJ5 +28830 IGLJ4 HGNC:HGNC:5866|IMGT/GENE-DB:IGLJ4 +28831 IGLJ3 HGNC:HGNC:5865|IMGT/GENE-DB:IGLJ3 +28832 IGLJ2 HGNC:HGNC:5864|IMGT/GENE-DB:IGLJ2 +28833 IGLJ1 HGNC:HGNC:5863|IMGT/GENE-DB:IGLJ1 +28834 IGLC7 HGNC:HGNC:5861|IMGT/GENE-DB:IGLC7 +28847 IGKV2OR22-4 HGNC:HGNC:5813|IMGT/GENE-DB:IGKV2/OR22-4 +28850 IGKV1OR22-5 HGNC:HGNC:5773|IMGT/GENE-DB:IGKV1/OR22-5 +28854 IGKV3OR2-5 HGNC:HGNC:5832|IMGT/GENE-DB:IGKV3/OR2-5 +28855 IGKV2OR2-10 HGNC:HGNC:5806|IMGT/GENE-DB:IGKV2/OR2-10 +28858 IGKV2OR2-4 HGNC:HGNC:5809|IMGT/GENE-DB:IGKV2/OR2-4 +28859 IGKV2OR2-2 HGNC:HGNC:5808|IMGT/GENE-DB:IGKV2/OR2-2 +28861 IGKV2OR2-1 HGNC:HGNC:5805|IMGT/GENE-DB:IGKV2/OR2-1 +28862 IGKV1OR2-108 MIM:147185|HGNC:HGNC:5767|IMGT/GENE-DB:IGKV1/OR2-108 +28863 IGKV1OR2-11 HGNC:HGNC:5768|IMGT/GENE-DB:IGKV1/OR2-11 +28864 IGKV1OR2-9 HGNC:HGNC:5771|IMGT/GENE-DB:IGKV1/OR2-9 +28865 IGKV1OR2-6 HGNC:HGNC:5770|IMGT/GENE-DB:IGKV1/OR2-6 +28866 IGKV1OR2-3 HGNC:HGNC:5769|IMGT/GENE-DB:IGKV1/OR2-3 +28867 IGKV1OR2-0 HGNC:HGNC:5766|IMGT/GENE-DB:IGKV1/OR2-0 +28869 IGKV6D-41 HGNC:HGNC:5838|IMGT/GENE-DB:IGKV6D-41 +28870 IGKV6D-21 HGNC:HGNC:5837|IMGT/GENE-DB:IGKV6D-21 +28871 IGKV3D-34 HGNC:HGNC:5828|IMGT/GENE-DB:IGKV3D-34 +28872 IGKV3D-31 HGNC:HGNC:5827|IMGT/GENE-DB:IGKV3D-31 +28873 IGKV3D-25 HGNC:HGNC:5826|IMGT/GENE-DB:IGKV3D-25 +28874 IGKV3D-20 HGNC:HGNC:5825|IMGT/GENE-DB:IGKV3D-20 +28875 IGKV3D-15 HGNC:HGNC:5824|IMGT/GENE-DB:IGKV3D-15 +28876 IGKV3D-11 HGNC:HGNC:5823|IMGT/GENE-DB:IGKV3D-11 +28877 IGKV3D-7 HGNC:HGNC:5829|IMGT/GENE-DB:IGKV3D-7 +28878 IGKV2D-40 HGNC:HGNC:5804|IMGT/GENE-DB:IGKV2D-40 +28879 IGKV2D-38 HGNC:HGNC:5803|IMGT/GENE-DB:IGKV2D-38 +28880 IGKV2D-36 HGNC:HGNC:5802|IMGT/GENE-DB:IGKV2D-36 +28881 IGKV2D-30 HGNC:HGNC:5801|IMGT/GENE-DB:IGKV2D-30 +28882 IGKV2D-29 HGNC:HGNC:5800|IMGT/GENE-DB:IGKV2D-29 +28883 IGKV2D-28 HGNC:HGNC:5799|IMGT/GENE-DB:IGKV2D-28 +28884 IGKV2D-26 HGNC:HGNC:5798|IMGT/GENE-DB:IGKV2D-26 +28885 IGKV2D-24 HGNC:HGNC:5797|IMGT/GENE-DB:IGKV2D-24 +28886 IGKV2D-23 HGNC:HGNC:5796|IMGT/GENE-DB:IGKV2D-23 +28887 IGKV2D-19 HGNC:HGNC:5795|IMGT/GENE-DB:IGKV2D-19 +28888 IGKV2D-18 HGNC:HGNC:5794|IMGT/GENE-DB:IGKV2D-18 +28889 IGKV2D-14 HGNC:HGNC:5793|IMGT/GENE-DB:IGKV2D-14 +28890 IGKV2D-10 HGNC:HGNC:5792|IMGT/GENE-DB:IGKV2D-10 +28891 IGKV1D-43 HGNC:HGNC:5758|IMGT/GENE-DB:IGKV1D-43 +28892 IGKV1D-42 HGNC:HGNC:5757|IMGT/GENE-DB:IGKV1D-42 +28893 IGKV1D-39 HGNC:HGNC:5756|IMGT/GENE-DB:IGKV1D-39 +28894 IGKV1D-37 HGNC:HGNC:5755|IMGT/GENE-DB:IGKV1D-37 +28895 IGKV1D-35 HGNC:HGNC:5754|IMGT/GENE-DB:IGKV1D-35 +28896 IGKV1D-33 HGNC:HGNC:5753|IMGT/GENE-DB:IGKV1D-33 +28897 IGKV1D-32 HGNC:HGNC:5752|IMGT/GENE-DB:IGKV1D-32 +28898 IGKV1D-27 HGNC:HGNC:5751|IMGT/GENE-DB:IGKV1D-27 +28899 IGKV1D-22 HGNC:HGNC:5750|IMGT/GENE-DB:IGKV1D-22 +28900 IGKV1D-17 HGNC:HGNC:5749|IMGT/GENE-DB:IGKV1D-17 +28901 IGKV1D-16 HGNC:HGNC:5748|IMGT/GENE-DB:IGKV1D-16 +28902 IGKV1D-13 HGNC:HGNC:5747|IMGT/GENE-DB:IGKV1D-13 +28903 IGKV1D-12 HGNC:HGNC:5746|IMGT/GENE-DB:IGKV1D-12 +28904 IGKV1D-8 HGNC:HGNC:5759|IMGT/GENE-DB:IGKV1D-8 +28905 IGKV7-3 HGNC:HGNC:5839|IMGT/GENE-DB:IGKV7-3 +28906 IGKV6-21 HGNC:HGNC:5836|IMGT/GENE-DB:IGKV6-21 +28907 IGKV5-2 HGNC:HGNC:5835|IMGT/GENE-DB:IGKV5-2 +28908 IGKV4-1 HGNC:HGNC:5834|IMGT/GENE-DB:IGKV4-1 +28909 IGKV3-34 HGNC:HGNC:5820|IMGT/GENE-DB:IGKV3-34 +28910 IGKV3-31 HGNC:HGNC:5819|IMGT/GENE-DB:IGKV3-31 +28911 IGKV3-25 HGNC:HGNC:5818|IMGT/GENE-DB:IGKV3-25 +28912 IGKV3-20 HGNC:HGNC:5817|IMGT/GENE-DB:IGKV3-20 +28913 IGKV3-15 HGNC:HGNC:5816|IMGT/GENE-DB:IGKV3-15 +28914 IGKV3-11 HGNC:HGNC:5815|IMGT/GENE-DB:IGKV3-11 +28915 IGKV3-7 HGNC:HGNC:5821|IMGT/GENE-DB:IGKV3-7 +28916 IGKV2-40 HGNC:HGNC:5789|IMGT/GENE-DB:IGKV2-40 +28917 IGKV2-38 HGNC:HGNC:5787|IMGT/GENE-DB:IGKV2-38 +28918 IGKV2-36 HGNC:HGNC:5786|IMGT/GENE-DB:IGKV2-36 +28919 IGKV2-30 HGNC:HGNC:5785|IMGT/GENE-DB:IGKV2-30 +28920 IGKV2-29 HGNC:HGNC:5784|IMGT/GENE-DB:IGKV2-29 +28921 IGKV2-28 HGNC:HGNC:5783|IMGT/GENE-DB:IGKV2-28 +28922 IGKV2-26 HGNC:HGNC:5782|IMGT/GENE-DB:IGKV2-26 +28923 IGKV2-24 HGNC:HGNC:5781|IMGT/GENE-DB:IGKV2-24 +28924 IGKV2-23 HGNC:HGNC:5780|IMGT/GENE-DB:IGKV2-23 +28925 IGKV2-19 HGNC:HGNC:5779|IMGT/GENE-DB:IGKV2-19 +28926 IGKV2-18 HGNC:HGNC:5778|IMGT/GENE-DB:IGKV2-18 +28927 IGKV2-14 HGNC:HGNC:5777|IMGT/GENE-DB:IGKV2-14 +28928 IGKV2-10 HGNC:HGNC:5776|IMGT/GENE-DB:IGKV2-10 +28929 IGKV2-4 HGNC:HGNC:5788|IMGT/GENE-DB:IGKV2-4 +28930 IGKV1-39 HGNC:HGNC:5740|IMGT/GENE-DB:IGKV1-39 +28931 IGKV1-37 HGNC:HGNC:5739|IMGT/GENE-DB:IGKV1-37 +28932 IGKV1-35 HGNC:HGNC:5738|IMGT/GENE-DB:IGKV1-35 +28933 IGKV1-33 HGNC:HGNC:5737|IMGT/GENE-DB:IGKV1-33 +28934 IGKV1-32 HGNC:HGNC:5736|IMGT/GENE-DB:IGKV1-32 +28935 IGKV1-27 HGNC:HGNC:5735|IMGT/GENE-DB:IGKV1-27 +28936 IGKV1-22 HGNC:HGNC:5734|IMGT/GENE-DB:IGKV1-22 +28937 IGKV1-17 HGNC:HGNC:5733|IMGT/GENE-DB:IGKV1-17 +28938 IGKV1-16 HGNC:HGNC:5732|IMGT/GENE-DB:IGKV1-16 +28939 IGKV1-13 HGNC:HGNC:5731|IMGT/GENE-DB:IGKV1-13 +28940 IGKV1-12 HGNC:HGNC:5730|IMGT/GENE-DB:IGKV1-12 +28941 IGKV1-9 HGNC:HGNC:5744|IMGT/GENE-DB:IGKV1-9 +28942 IGKV1-8 HGNC:HGNC:5743|IMGT/GENE-DB:IGKV1-8 +28943 IGKV1-6 HGNC:HGNC:5742|IMGT/GENE-DB:IGKV1-6 +28946 IGKJ5 HGNC:HGNC:5723|IMGT/GENE-DB:IGKJ5 +28947 IGKJ4 HGNC:HGNC:5722|IMGT/GENE-DB:IGKJ4 +28948 IGKJ3 HGNC:HGNC:5721|IMGT/GENE-DB:IGKJ3 +28949 IGKJ2 HGNC:HGNC:5720|IMGT/GENE-DB:IGKJ2 +28950 IGKJ1 HGNC:HGNC:5719|IMGT/GENE-DB:IGKJ1 +28951 TRIB2 MIM:609462|HGNC:HGNC:30809|Ensembl:ENSG00000071575|Vega:OTTHUMG00000090575 +28952 CCDC22 MIM:300859|HGNC:HGNC:28909|Ensembl:ENSG00000101997|Vega:OTTHUMG00000024141 +28954 REM1 MIM:610388|HGNC:HGNC:15922|Ensembl:ENSG00000088320|Vega:OTTHUMG00000032168 +28955 DEXI HGNC:HGNC:13267|Ensembl:ENSG00000182108|Vega:OTTHUMG00000129785 +28956 LAMTOR2 MIM:610389|HGNC:HGNC:29796|Ensembl:ENSG00000116586|Vega:OTTHUMG00000017462 +28957 MRPS28 MIM:611990|HGNC:HGNC:14513|Ensembl:ENSG00000147586|Vega:OTTHUMG00000164642 +28958 COA3 MIM:614775|HGNC:HGNC:24990|Ensembl:ENSG00000183978|Vega:OTTHUMG00000180651 +28959 TMEM176B MIM:610385|HGNC:HGNC:29596|Ensembl:ENSG00000106565|Vega:OTTHUMG00000157577 +28960 DCPS MIM:610534|HGNC:HGNC:29812|Ensembl:ENSG00000110063|Vega:OTTHUMG00000165829 +28962 OSTM1 MIM:607649|HGNC:HGNC:21652|Ensembl:ENSG00000081087|Vega:OTTHUMG00000015317 +28964 GIT1 MIM:608434|HGNC:HGNC:4272|Ensembl:ENSG00000108262|Vega:OTTHUMG00000132730 +28965 SLC27A6 MIM:604196|HGNC:HGNC:11000|Ensembl:ENSG00000113396|Vega:OTTHUMG00000128991 +28966 SNX24 HGNC:HGNC:21533|Ensembl:ENSG00000064652|Vega:OTTHUMG00000128913 +28968 SLC6A16 MIM:607972|HGNC:HGNC:13622|Ensembl:ENSG00000063127|Vega:OTTHUMG00000183179 +28969 BZW2 HGNC:HGNC:18808|Ensembl:ENSG00000136261|Vega:OTTHUMG00000130755 +28970 C11orf54 MIM:615810|HGNC:HGNC:30204|Ensembl:ENSG00000182919|Vega:OTTHUMG00000167452 +28971 AAMDC HGNC:HGNC:30205|Ensembl:ENSG00000087884|Vega:OTTHUMG00000166651 +28972 SPCS1 MIM:610358|HGNC:HGNC:23401|Ensembl:ENSG00000114902|Vega:OTTHUMG00000154930 +28973 MRPS18B MIM:611982|HGNC:HGNC:14516|Ensembl:ENSG00000204568|Vega:OTTHUMG00000031268 +28974 C19orf53 HGNC:HGNC:24991|Ensembl:ENSG00000104979|Vega:OTTHUMG00000180914 +28976 ACAD9 MIM:611103|HGNC:HGNC:21497|Ensembl:ENSG00000177646|Vega:OTTHUMG00000159942 +28977 MRPL42 MIM:611847|HGNC:HGNC:14493|Ensembl:ENSG00000198015|Vega:OTTHUMG00000170157 +28978 TMEM14A MIM:616870|HGNC:HGNC:21076|Ensembl:ENSG00000096092|Vega:OTTHUMG00000014856 +28981 IFT81 MIM:605489|HGNC:HGNC:14313|Ensembl:ENSG00000122970|Vega:OTTHUMG00000169326 +28982 FLVCR1 MIM:609144|HGNC:HGNC:24682|Ensembl:ENSG00000162769|Vega:OTTHUMG00000036924 +28983 TMPRSS11E MIM:610399|HGNC:HGNC:24465|Ensembl:ENSG00000087128|Vega:OTTHUMG00000160438 +28984 RGCC MIM:610077|HGNC:HGNC:20369|Ensembl:ENSG00000102760|Vega:OTTHUMG00000016796 +28985 MCTS1 MIM:300587|HGNC:HGNC:23357|Ensembl:ENSG00000232119|Vega:OTTHUMG00000022303 +28986 MAGEH1 MIM:300548|HGNC:HGNC:24092|Ensembl:ENSG00000187601|Vega:OTTHUMG00000021655 +28987 NOB1 MIM:613586|HGNC:HGNC:29540|Ensembl:ENSG00000141101|Vega:OTTHUMG00000137576 +28988 DBNL MIM:610106|HGNC:HGNC:2696|Ensembl:ENSG00000136279|Vega:OTTHUMG00000155350 +28989 NTMT1 MIM:613560|HGNC:HGNC:23373|Ensembl:ENSG00000148335|Vega:OTTHUMG00000020785 +28990 ASTE1 HGNC:HGNC:25021|Ensembl:ENSG00000034533|Vega:OTTHUMG00000159644 +28991 COMMD5 MIM:608216|HGNC:HGNC:17902|Ensembl:ENSG00000170619|Vega:OTTHUMG00000165251 +28992 MACROD1 MIM:610400|HGNC:HGNC:29598|Ensembl:ENSG00000133315|Vega:OTTHUMG00000167843 +28996 HIPK2 MIM:606868|HGNC:HGNC:14402|Ensembl:ENSG00000064393|Vega:OTTHUMG00000157704 +28998 MRPL13 MIM:610200|HGNC:HGNC:14278|Ensembl:ENSG00000172172|Vega:OTTHUMG00000165039 +28999 KLF15 MIM:606465|HGNC:HGNC:14536|Ensembl:ENSG00000163884|Vega:OTTHUMG00000162689 +29015 SLC43A3 HGNC:HGNC:17466|Ensembl:ENSG00000134802|Vega:OTTHUMG00000167113 +29018 FOXN3-AS2 HGNC:HGNC:30119|Ensembl:ENSG00000259073 +29028 ATAD2 MIM:611941|HGNC:HGNC:30123|Ensembl:ENSG00000156802|Vega:OTTHUMG00000165090 +29034 CPS1-IT1 HGNC:HGNC:30102|Ensembl:ENSG00000280837 +29035 C16orf72 HGNC:HGNC:30103|Ensembl:ENSG00000182831|Vega:OTTHUMG00000178147 +29057 FAM156A HGNC:HGNC:30114|Ensembl:ENSG00000268350|Vega:OTTHUMG00000188220 +29058 TMEM230 MIM:617019|HGNC:HGNC:15876|Ensembl:ENSG00000089063|Vega:OTTHUMG00000031796 +29062 WDR91 MIM:616303|HGNC:HGNC:24997|Ensembl:ENSG00000105875|Vega:OTTHUMG00000155414 +29063 ZCCHC4 MIM:611792|HGNC:HGNC:22917|Ensembl:ENSG00000168228|Vega:OTTHUMG00000160563 +29065 ASAP1-IT1 HGNC:HGNC:24998 +29066 ZC3H7A HGNC:HGNC:30959|Ensembl:ENSG00000122299|Vega:OTTHUMG00000129825 +29068 ZBTB44 HGNC:HGNC:25001|Ensembl:ENSG00000196323|Vega:OTTHUMG00000165769 +29070 CCDC113 MIM:616070|HGNC:HGNC:25002|Ensembl:ENSG00000103021|Vega:OTTHUMG00000133489 +29071 C1GALT1C1 MIM:300611|HGNC:HGNC:24338|Ensembl:ENSG00000171155|Vega:OTTHUMG00000022305 +29072 SETD2 MIM:612778|HGNC:HGNC:18420|Ensembl:ENSG00000181555|Vega:OTTHUMG00000133514 +29074 MRPL18 MIM:611831|HGNC:HGNC:14477|Ensembl:ENSG00000112110|Vega:OTTHUMG00000015942 +29075 LINC00652 HGNC:HGNC:25003 +29078 NDUFAF4 MIM:611776|HGNC:HGNC:21034|Ensembl:ENSG00000123545|Vega:OTTHUMG00000015246 +29079 MED4 MIM:605718|HGNC:HGNC:17903|Ensembl:ENSG00000136146|Vega:OTTHUMG00000016891 +29080 CCDC59 HGNC:HGNC:25005|Ensembl:ENSG00000133773|Vega:OTTHUMG00000170251 +29081 METTL5 HGNC:HGNC:25006|Ensembl:ENSG00000138382|Vega:OTTHUMG00000154117 +29082 CHMP4A MIM:610051|HGNC:HGNC:20274|Ensembl:ENSG00000254505|Vega:OTTHUMG00000167036 +29083 GTPBP8 HGNC:HGNC:25007|Ensembl:ENSG00000163607|Vega:OTTHUMG00000159268 +29085 PHPT1 MIM:610167|HGNC:HGNC:30033|Ensembl:ENSG00000054148|Vega:OTTHUMG00000020950 +29086 BABAM1 MIM:612766|HGNC:HGNC:25008|Ensembl:ENSG00000105393|Vega:OTTHUMG00000182755 +29087 THYN1 MIM:613739|HGNC:HGNC:29560|Ensembl:ENSG00000151500|Vega:OTTHUMG00000167176 +29088 MRPL15 MIM:611828|HGNC:HGNC:14054|Ensembl:ENSG00000137547|Vega:OTTHUMG00000164315 +29089 UBE2T MIM:610538|HGNC:HGNC:25009|Ensembl:ENSG00000077152|Vega:OTTHUMG00000041392 +29090 TIMM21 MIM:615180|HGNC:HGNC:25010|Ensembl:ENSG00000075336|Vega:OTTHUMG00000132844 +29091 STXBP6 MIM:607958|HGNC:HGNC:19666|Ensembl:ENSG00000168952|Vega:OTTHUMG00000140186 +29092 LINC00339 HGNC:HGNC:25011|Ensembl:ENSG00000218510 +29093 MRPL22 MIM:611835|HGNC:HGNC:14480|Ensembl:ENSG00000082515|Vega:OTTHUMG00000130190 +29094 LGALSL HGNC:HGNC:25012|Ensembl:ENSG00000119862|Vega:OTTHUMG00000129541 +29095 ORMDL2 MIM:610074|HGNC:HGNC:16037|Ensembl:ENSG00000123353|Vega:OTTHUMG00000170202 +29097 CNIH4 MIM:617483|HGNC:HGNC:25013|Ensembl:ENSG00000143771|Vega:OTTHUMG00000037635 +29098 RANGRF MIM:607954|HGNC:HGNC:17679|Ensembl:ENSG00000108961|Vega:OTTHUMG00000178473 +29099 COMMD9 MIM:612299|HGNC:HGNC:25014|Ensembl:ENSG00000110442|Vega:OTTHUMG00000166333 +29100 TMEM208 HGNC:HGNC:25015|Ensembl:ENSG00000168701|Vega:OTTHUMG00000173064 +29101 SSU72 HGNC:HGNC:25016|Ensembl:ENSG00000160075|Vega:OTTHUMG00000000576 +29102 DROSHA MIM:608828|HGNC:HGNC:17904|Ensembl:ENSG00000113360|Vega:OTTHUMG00000161976 +29103 DNAJC15 MIM:615339|HGNC:HGNC:20325|Ensembl:ENSG00000120675|Vega:OTTHUMG00000016813 +29104 N6AMT1 MIM:614553|HGNC:HGNC:16021|Ensembl:ENSG00000156239|Vega:OTTHUMG00000078750 +29105 CFAP20 HGNC:HGNC:29523|Ensembl:ENSG00000070761|Vega:OTTHUMG00000133490 +29106 SCG3 MIM:611796|HGNC:HGNC:13707|Ensembl:ENSG00000104112|Vega:OTTHUMG00000131748 +29107 NXT1 MIM:605811|HGNC:HGNC:15913|Ensembl:ENSG00000132661|Vega:OTTHUMG00000032059 +29108 PYCARD MIM:606838|HGNC:HGNC:16608|Ensembl:ENSG00000103490|Vega:OTTHUMG00000176753 +29109 FHOD1 MIM:606881|HGNC:HGNC:17905|Ensembl:ENSG00000135723|Vega:OTTHUMG00000137521 +29110 TBK1 MIM:604834|HGNC:HGNC:11584|Ensembl:ENSG00000183735|Vega:OTTHUMG00000168796 +29113 C6orf15 MIM:611401|HGNC:HGNC:13927|Ensembl:ENSG00000204542|Vega:OTTHUMG00000031111 +29114 TAGLN3 MIM:607953|HGNC:HGNC:29868|Ensembl:ENSG00000144834|Vega:OTTHUMG00000159281 +29115 SAP30BP MIM:610218|HGNC:HGNC:30785|Ensembl:ENSG00000161526|Vega:OTTHUMG00000179798 +29116 MYLIP MIM:610082|HGNC:HGNC:21155|Ensembl:ENSG00000007944|Vega:OTTHUMG00000016405 +29117 BRD7 HGNC:HGNC:14310|Ensembl:ENSG00000166164|Vega:OTTHUMG00000133170 +29118 DDX25 MIM:607663|HGNC:HGNC:18698|Ensembl:ENSG00000109832|Vega:OTTHUMG00000165859 +29119 CTNNA3 MIM:607667|HGNC:HGNC:2511|Ensembl:ENSG00000183230|Vega:OTTHUMG00000018334 +29121 CLEC2D MIM:605659|HGNC:HGNC:14351|Ensembl:ENSG00000069493|Vega:OTTHUMG00000168369 +29122 PRSS50 MIM:607950|HGNC:HGNC:17910|Ensembl:ENSG00000206549|Ensembl:ENSG00000283706|Vega:OTTHUMG00000164067 +29123 ANKRD11 MIM:611192|HGNC:HGNC:21316|Ensembl:ENSG00000167522|Vega:OTTHUMG00000175548 +29124 LGALS13 MIM:608717|HGNC:HGNC:15449|Ensembl:ENSG00000105198|Vega:OTTHUMG00000183073 +29125 C11orf21 MIM:611033|HGNC:HGNC:13231|Ensembl:ENSG00000110665|Vega:OTTHUMG00000009759 +29126 CD274 MIM:605402|HGNC:HGNC:17635|Ensembl:ENSG00000120217|Vega:OTTHUMG00000019503 +29127 RACGAP1 MIM:604980|HGNC:HGNC:9804|Ensembl:ENSG00000161800|Vega:OTTHUMG00000169811 +29128 UHRF1 MIM:607990|HGNC:HGNC:12556|Ensembl:ENSG00000276043|Vega:OTTHUMG00000180251 +29760 BLNK MIM:604515|HGNC:HGNC:14211|Ensembl:ENSG00000095585|Vega:OTTHUMG00000018827 +29761 USP25 MIM:604736|HGNC:HGNC:12624|Ensembl:ENSG00000155313|Vega:OTTHUMG00000074343 +29763 PACSIN3 MIM:606513|HGNC:HGNC:8572|Ensembl:ENSG00000165912|Vega:OTTHUMG00000166870 +29764 DDU MIM:125630|HGNC:HGNC:2733 +29765 TMOD4 MIM:605834|HGNC:HGNC:11874|Ensembl:ENSG00000163157|Vega:OTTHUMG00000012350 +29766 TMOD3 MIM:605112|HGNC:HGNC:11873|Ensembl:ENSG00000138594|Vega:OTTHUMG00000131803 +29767 TMOD2 MIM:602928|HGNC:HGNC:11872|Ensembl:ENSG00000128872|Vega:OTTHUMG00000131805 +29768 SDHDP6 HGNC:HGNC:10689 +29769 SDHDP5 HGNC:HGNC:10688 +29770 SDHDP4 HGNC:HGNC:10687 +29771 SDHDP3 HGNC:HGNC:10686 +29774 POM121L9P HGNC:HGNC:30080|Ensembl:ENSG00000128262 +29775 CARD10 MIM:607209|HGNC:HGNC:16422|Ensembl:ENSG00000100065|Vega:OTTHUMG00000150592 +29777 ABT1 HGNC:HGNC:17369|Ensembl:ENSG00000146109|Vega:OTTHUMG00000016319 +29778 MAP2K1P1 HGNC:HGNC:6841 +29779 DFNA33 MIM:614211|HGNC:HGNC:2805 +29780 PARVB MIM:608121|HGNC:HGNC:14653|Ensembl:ENSG00000188677|Vega:OTTHUMG00000150665 +29781 NCAPH2 MIM:611230|HGNC:HGNC:25071|Ensembl:ENSG00000025770|Vega:OTTHUMG00000150205 +29785 CYP2S1 MIM:611529|HGNC:HGNC:15654|Ensembl:ENSG00000167600|Vega:OTTHUMG00000182721 +29789 OLA1 MIM:611175|HGNC:HGNC:28833|Ensembl:ENSG00000138430|Vega:OTTHUMG00000132335 +29796 UQCR10 MIM:610843|HGNC:HGNC:30863|Ensembl:ENSG00000184076|Vega:OTTHUMG00000151283 +29797 POM121L8P HGNC:HGNC:35446 +29798 C2orf27A HGNC:HGNC:25077 +29799 YPEL1 MIM:608082|HGNC:HGNC:12845|Ensembl:ENSG00000100027|Vega:OTTHUMG00000150830 +29800 ZDHHC1 HGNC:HGNC:17916|Ensembl:ENSG00000159714|Vega:OTTHUMG00000137522 +29801 ZDHHC8 MIM:608784|HGNC:HGNC:18474|Ensembl:ENSG00000099904|Vega:OTTHUMG00000150499 +29802 VPREB3 MIM:605017|HGNC:HGNC:12710|Ensembl:ENSG00000128218|IMGT/GENE-DB:VPREB3|Vega:OTTHUMG00000150738 +29803 REPIN1 HGNC:HGNC:17922|Ensembl:ENSG00000214022|Vega:OTTHUMG00000158330 +29841 GRHL1 MIM:609786|HGNC:HGNC:17923|Ensembl:ENSG00000134317|Vega:OTTHUMG00000151704 +29842 TFCP2L1 MIM:609785|HGNC:HGNC:17925|Ensembl:ENSG00000115112|Vega:OTTHUMG00000131443 +29843 SENP1 MIM:612157|HGNC:HGNC:17927|Ensembl:ENSG00000079387|Vega:OTTHUMG00000169896 +29844 TFPT MIM:609519|HGNC:HGNC:13630|Ensembl:ENSG00000105619|Vega:OTTHUMG00000065906 +29850 TRPM5 MIM:604600|HGNC:HGNC:14323|Ensembl:ENSG00000070985|Vega:OTTHUMG00000009896 +29851 ICOS MIM:604558|HGNC:HGNC:5351|Ensembl:ENSG00000163600|Vega:OTTHUMG00000132880 +29855 UBN1 MIM:609771|HGNC:HGNC:12506|Ensembl:ENSG00000118900|Vega:OTTHUMG00000129531 +29880 ALG5 MIM:604565|HGNC:HGNC:20266|Ensembl:ENSG00000120697|Vega:OTTHUMG00000016741 +29881 NPC1L1 MIM:608010|HGNC:HGNC:7898|Ensembl:ENSG00000015520|Vega:OTTHUMG00000023691 +29882 ANAPC2 MIM:606946|HGNC:HGNC:19989|Ensembl:ENSG00000176248|Vega:OTTHUMG00000020983 +29883 CNOT7 MIM:604913|HGNC:HGNC:14101|Ensembl:ENSG00000198791|Vega:OTTHUMG00000096971 +29886 SNX8 MIM:614905|HGNC:HGNC:14972|Ensembl:ENSG00000106266|Vega:OTTHUMG00000151512 +29887 SNX10 MIM:614780|HGNC:HGNC:14974|Ensembl:ENSG00000086300|Vega:OTTHUMG00000023650 +29888 STRN4 MIM:614767|HGNC:HGNC:15721|Ensembl:ENSG00000090372|Vega:OTTHUMG00000183432 +29889 GNL2 MIM:609365|HGNC:HGNC:29925|Ensembl:ENSG00000134697|Vega:OTTHUMG00000004322 +29890 RBM15B MIM:612602|HGNC:HGNC:24303|Ensembl:ENSG00000259956|Vega:OTTHUMG00000156896 +29893 PSMC3IP MIM:608665|HGNC:HGNC:17928|Ensembl:ENSG00000131470|Vega:OTTHUMG00000180247 +29894 CPSF1 MIM:606027|HGNC:HGNC:2324|Ensembl:ENSG00000071894|Vega:OTTHUMG00000174612 +29895 MYLPF MIM:617378|HGNC:HGNC:29824|Ensembl:ENSG00000180209|Vega:OTTHUMG00000132399 +29896 TRA2A MIM:602718|HGNC:HGNC:16645|Ensembl:ENSG00000164548|Vega:OTTHUMG00000128459 +29899 GPSM2 MIM:609245|HGNC:HGNC:29501|Ensembl:ENSG00000121957|Vega:OTTHUMG00000011730 +29901 SAC3D1 HGNC:HGNC:30179|Ensembl:ENSG00000168061|Vega:OTTHUMG00000165594 +29902 FAM216A HGNC:HGNC:30180|Ensembl:ENSG00000204856|Vega:OTTHUMG00000169526 +29903 CCDC106 MIM:613478|HGNC:HGNC:30181|Ensembl:ENSG00000173581|Vega:OTTHUMG00000180907 +29904 EEF2K MIM:606968|HGNC:HGNC:24615|Ensembl:ENSG00000103319|Vega:OTTHUMG00000094771 +29906 ST8SIA5 MIM:607162|HGNC:HGNC:17827|Ensembl:ENSG00000101638|Vega:OTTHUMG00000132643 +29907 SNX15 MIM:605964|HGNC:HGNC:14978|Ensembl:ENSG00000110025|Vega:OTTHUMG00000037387 +29909 GPR171 HGNC:HGNC:30057|Ensembl:ENSG00000174946|Vega:OTTHUMG00000159861 +29911 HOOK2 MIM:607824|HGNC:HGNC:19885|Ensembl:ENSG00000095066|Vega:OTTHUMG00000180372 +29914 UBIAD1 MIM:611632|HGNC:HGNC:30791|Ensembl:ENSG00000120942|Vega:OTTHUMG00000002075 +29915 HCFC2 MIM:607926|HGNC:HGNC:24972|Ensembl:ENSG00000111727|Vega:OTTHUMG00000170175 +29916 SNX11 MIM:614906|HGNC:HGNC:14975|Ensembl:ENSG00000002919|Vega:OTTHUMG00000178822 +29919 C18orf8 HGNC:HGNC:24326|Ensembl:ENSG00000141452|Vega:OTTHUMG00000179239 +29920 PYCR2 MIM:616406|HGNC:HGNC:30262|Ensembl:ENSG00000143811|Vega:OTTHUMG00000037506 +29922 NME7 MIM:613465|HGNC:HGNC:20461|Ensembl:ENSG00000143156|Vega:OTTHUMG00000034586 +29923 HILPDA HGNC:HGNC:28859|Ensembl:ENSG00000135245|Vega:OTTHUMG00000157712 +29924 EPN1 MIM:607262|HGNC:HGNC:21604|Ensembl:ENSG00000063245|Vega:OTTHUMG00000180911 +29925 GMPPB MIM:615320|HGNC:HGNC:22932|Ensembl:ENSG00000173540|Vega:OTTHUMG00000158151 +29926 GMPPA MIM:615495|HGNC:HGNC:22923|Ensembl:ENSG00000144591|Vega:OTTHUMG00000058922 +29927 SEC61A1 MIM:609213|HGNC:HGNC:18276|Ensembl:ENSG00000058262|Vega:OTTHUMG00000159624 +29928 TIMM22 MIM:607251|HGNC:HGNC:17317|Ensembl:ENSG00000177370|Vega:OTTHUMG00000180175 +29929 ALG6 MIM:604566|HGNC:HGNC:23157|Ensembl:ENSG00000088035|Vega:OTTHUMG00000009140 +29930 PCDHB1 MIM:606327|HGNC:HGNC:8680|Ensembl:ENSG00000171815|Vega:OTTHUMG00000129627 +29931 LINC00312 MIM:610485|HGNC:HGNC:6662 +29933 GPR132 MIM:606167|HGNC:HGNC:17482|Ensembl:ENSG00000183484|Vega:OTTHUMG00000140173 +29934 SNX12 MIM:300883|HGNC:HGNC:14976|Ensembl:ENSG00000147164|Vega:OTTHUMG00000021786 +29935 RPA4 MIM:300767|HGNC:HGNC:30305|Ensembl:ENSG00000204086|Vega:OTTHUMG00000021987 +29937 NENF MIM:611874|HGNC:HGNC:30384|Ensembl:ENSG00000117691|Vega:OTTHUMG00000036744 +29940 DSE MIM:605942|HGNC:HGNC:21144|Ensembl:ENSG00000111817|Ensembl:ENSG00000237021|Ensembl:ENSG00000240050|Vega:OTTHUMG00000015434 +29941 PKN3 MIM:610714|HGNC:HGNC:17999|Ensembl:ENSG00000160447|Vega:OTTHUMG00000020757 +29942 PURG HGNC:HGNC:17930|Ensembl:ENSG00000172733|Vega:OTTHUMG00000157357 +29943 PADI1 MIM:607934|HGNC:HGNC:18367|Ensembl:ENSG00000142623|Vega:OTTHUMG00000002294 +29944 PNMA3 MIM:300675|HGNC:HGNC:18742|Ensembl:ENSG00000183837|Vega:OTTHUMG00000024195 +29945 ANAPC4 MIM:606947|HGNC:HGNC:19990|Ensembl:ENSG00000053900|Vega:OTTHUMG00000097753 +29946 SERTAD3 MIM:612125|HGNC:HGNC:17931|Ensembl:ENSG00000167565|Vega:OTTHUMG00000182595 +29947 DNMT3L MIM:606588|HGNC:HGNC:2980|Ensembl:ENSG00000142182|Vega:OTTHUMG00000086914 +29948 OSGIN1 MIM:607975|HGNC:HGNC:30093|Ensembl:ENSG00000140961|Vega:OTTHUMG00000137640 +29949 IL19 MIM:605687|HGNC:HGNC:5990|Ensembl:ENSG00000142224|Vega:OTTHUMG00000036387 +29950 SERTAD1 HGNC:HGNC:17932|Ensembl:ENSG00000197019|Vega:OTTHUMG00000182594 +29951 PDZRN4 MIM:609730|HGNC:HGNC:30552|Ensembl:ENSG00000165966|Vega:OTTHUMG00000169364 +29952 DPP7 MIM:610537|HGNC:HGNC:14892|Ensembl:ENSG00000176978|Vega:OTTHUMG00000020977 +29953 TRHDE MIM:606950|HGNC:HGNC:30748|Ensembl:ENSG00000072657|Vega:OTTHUMG00000169642 +29954 POMT2 MIM:607439|HGNC:HGNC:19743|Ensembl:ENSG00000009830|Vega:OTTHUMG00000171556 +29956 CERS2 MIM:606920|HGNC:HGNC:14076|Ensembl:ENSG00000143418|Vega:OTTHUMG00000035064 +29957 SLC25A24 MIM:608744|HGNC:HGNC:20662|Ensembl:ENSG00000085491|Vega:OTTHUMG00000011013 +29958 DMGDH MIM:605849|HGNC:HGNC:24475|Ensembl:ENSG00000132837|Vega:OTTHUMG00000108159 +29959 NRBP1 MIM:606010|HGNC:HGNC:7993|Ensembl:ENSG00000115216|Vega:OTTHUMG00000097789 +29960 MRM2 MIM:606906|HGNC:HGNC:16352|Ensembl:ENSG00000122687|Vega:OTTHUMG00000023866 +29964 PRICKLE4 MIM:611389|HGNC:HGNC:16805|Ensembl:ENSG00000124593|Ensembl:ENSG00000278224|Vega:OTTHUMG00000014685|Vega:OTTHUMG00000188149 +29965 CDIP1 MIM:610503|HGNC:HGNC:13234|Ensembl:ENSG00000089486|Vega:OTTHUMG00000177172 +29966 STRN3 MIM:614766|HGNC:HGNC:15720|Ensembl:ENSG00000196792|Vega:OTTHUMG00000140201 +29967 LRP12 HGNC:HGNC:31708|Ensembl:ENSG00000147650|Vega:OTTHUMG00000164892 +29968 PSAT1 MIM:610936|HGNC:HGNC:19129|Ensembl:ENSG00000135069|Vega:OTTHUMG00000020066 +29969 MDFIC MIM:614511|HGNC:HGNC:28870|Ensembl:ENSG00000135272|Vega:OTTHUMG00000023647 +29970 SCHIP1 HGNC:HGNC:15678|Ensembl:ENSG00000151967|Ensembl:ENSG00000283154|Vega:OTTHUMG00000158934 +29974 A1CF HGNC:HGNC:24086|Ensembl:ENSG00000148584|Vega:OTTHUMG00000018240 +29978 UBQLN2 MIM:300264|HGNC:HGNC:12509|Ensembl:ENSG00000188021|Vega:OTTHUMG00000021669 +29979 UBQLN1 MIM:605046|HGNC:HGNC:12508|Ensembl:ENSG00000135018|Vega:OTTHUMG00000020104 +29980 DONSON MIM:611428|HGNC:HGNC:2993|Ensembl:ENSG00000159147|Vega:OTTHUMG00000065904 +29982 NRBF2 MIM:616477|HGNC:HGNC:19692|Ensembl:ENSG00000148572|Vega:OTTHUMG00000018309 +29984 RHOD MIM:605781|HGNC:HGNC:670|Ensembl:ENSG00000173156|Vega:OTTHUMG00000167102 +29985 SLC39A3 MIM:612168|HGNC:HGNC:17128|Ensembl:ENSG00000141873|Vega:OTTHUMG00000180440 +29986 SLC39A2 MIM:612166|HGNC:HGNC:17127|Ensembl:ENSG00000165794|Vega:OTTHUMG00000029616 +29988 SLC2A8 MIM:605245|HGNC:HGNC:13812|Ensembl:ENSG00000136856|Vega:OTTHUMG00000020702 +29989 OBP2B MIM:604606|HGNC:HGNC:23381|Ensembl:ENSG00000171102|Vega:OTTHUMG00000020860 +29990 PILRB MIM:605342|HGNC:HGNC:18297|Ensembl:ENSG00000121716|Vega:OTTHUMG00000155363 +29991 OBP2A MIM:164320|HGNC:HGNC:23380|Ensembl:ENSG00000122136|Vega:OTTHUMG00000020909 +29992 PILRA MIM:605341|HGNC:HGNC:20396|Ensembl:ENSG00000085514|Vega:OTTHUMG00000155248 +29993 PACSIN1 MIM:606512|HGNC:HGNC:8570|Ensembl:ENSG00000124507|Vega:OTTHUMG00000014547 +29994 BAZ2B MIM:605683|HGNC:HGNC:963|Ensembl:ENSG00000123636|Ensembl:ENSG00000226266|Vega:OTTHUMG00000132027 +29995 LMCD1 MIM:604859|HGNC:HGNC:6633|Ensembl:ENSG00000071282|Vega:OTTHUMG00000154971 +29997 NOP53 MIM:605691|HGNC:HGNC:4333|Ensembl:ENSG00000105373|Vega:OTTHUMG00000183059 +29998 BICRA MIM:605690|HGNC:HGNC:4332|Ensembl:ENSG00000063169|Vega:OTTHUMG00000183263 +29999 FSCN3 MIM:615800|HGNC:HGNC:3961|Ensembl:ENSG00000106328|Vega:OTTHUMG00000022935 +30000 TNPO2 MIM:603002|HGNC:HGNC:19998|Ensembl:ENSG00000105576|Vega:OTTHUMG00000180333 +30001 ERO1A MIM:615435|HGNC:HGNC:13280|Ensembl:ENSG00000197930|Vega:OTTHUMG00000140301 +30008 EFEMP2 MIM:604633|HGNC:HGNC:3219|Ensembl:ENSG00000172638|Vega:OTTHUMG00000166664 +30009 TBX21 MIM:604895|HGNC:HGNC:11599|Ensembl:ENSG00000073861|Vega:OTTHUMG00000178287 +30010 NXPH1 MIM:604639|HGNC:HGNC:20693|Ensembl:ENSG00000122584|Vega:OTTHUMG00000151941 +30011 SH3KBP1 MIM:300374|HGNC:HGNC:13867|Ensembl:ENSG00000147010|Vega:OTTHUMG00000021227 +30012 TLX3 MIM:604640|HGNC:HGNC:13532|Ensembl:ENSG00000164438|Vega:OTTHUMG00000163207 +30014 SPANXA1 MIM:300305|HGNC:HGNC:11218|Ensembl:ENSG00000198021|Vega:OTTHUMG00000022564 +30061 SLC40A1 MIM:604653|HGNC:HGNC:10909|Ensembl:ENSG00000138449|Vega:OTTHUMG00000132662 +30062 RAX MIM:601881|HGNC:HGNC:18662|Ensembl:ENSG00000134438|Vega:OTTHUMG00000132757 +30811 HUNK MIM:606532|HGNC:HGNC:13326|Ensembl:ENSG00000142149|Vega:OTTHUMG00000085019 +30812 SOX8 MIM:605923|HGNC:HGNC:11203|Ensembl:ENSG00000005513|Vega:OTTHUMG00000122101 +30813 VSX1 MIM:605020|HGNC:HGNC:12723|Ensembl:ENSG00000100987|Vega:OTTHUMG00000032111 +30814 PLA2G2E HGNC:HGNC:13414|Ensembl:ENSG00000188784|Vega:OTTHUMG00000002702 +30815 ST6GALNAC6 MIM:610135|HGNC:HGNC:23364|Ensembl:ENSG00000160408|Vega:OTTHUMG00000020718 +30816 ERVW-1 MIM:604659|HGNC:HGNC:13525|Ensembl:ENSG00000242950|Vega:OTTHUMG00000131249 +30817 ADGRE2 MIM:606100|HGNC:HGNC:3337|Ensembl:ENSG00000127507|Vega:OTTHUMG00000183408 +30818 KCNIP3 MIM:604662|HGNC:HGNC:15523|Ensembl:ENSG00000115041|Vega:OTTHUMG00000130392 +30819 KCNIP2 MIM:604661|HGNC:HGNC:15522|Ensembl:ENSG00000120049|Vega:OTTHUMG00000018937 +30820 KCNIP1 MIM:604660|HGNC:HGNC:15521|Ensembl:ENSG00000182132|Vega:OTTHUMG00000130442 +30827 CXXC1 MIM:609150|HGNC:HGNC:24343|Ensembl:ENSG00000154832|Vega:OTTHUMG00000132670 +30829 IBD3 MIM:604519|HGNC:HGNC:13863 +30832 ZNF354C HGNC:HGNC:16736|Ensembl:ENSG00000177932|Vega:OTTHUMG00000130888 +30833 NT5C MIM:191720|HGNC:HGNC:17144|Ensembl:ENSG00000125458|Vega:OTTHUMG00000179346 +30834 ZNRD1 MIM:607525|HGNC:HGNC:13182|Ensembl:ENSG00000066379|Vega:OTTHUMG00000031149 +30835 CD209 MIM:604672|HGNC:HGNC:1641|Ensembl:ENSG00000090659|Vega:OTTHUMG00000182530 +30836 DNTTIP2 MIM:611199|HGNC:HGNC:24013|Ensembl:ENSG00000067334|Vega:OTTHUMG00000010268 +30837 SOCS7 MIM:608788|HGNC:HGNC:29846|Ensembl:ENSG00000274211|Vega:OTTHUMG00000188546 +30844 EHD4 MIM:605892|HGNC:HGNC:3245|Ensembl:ENSG00000103966|Vega:OTTHUMG00000130370 +30845 EHD3 MIM:605891|HGNC:HGNC:3244|Ensembl:ENSG00000013016|Vega:OTTHUMG00000099365 +30846 EHD2 MIM:605890|HGNC:HGNC:3243|Ensembl:ENSG00000024422|Vega:OTTHUMG00000183266 +30847 CECR9 HGNC:HGNC:1847 +30848 CTAG2 MIM:300396|HGNC:HGNC:2492|Ensembl:ENSG00000126890|Vega:OTTHUMG00000024239 +30849 PIK3R4 MIM:602610|HGNC:HGNC:8982|Ensembl:ENSG00000196455|Vega:OTTHUMG00000159645 +30850 CDR2L HGNC:HGNC:29999|Ensembl:ENSG00000109089|Vega:OTTHUMG00000150435 +30851 TAX1BP3 MIM:616484|HGNC:HGNC:30684|Ensembl:ENSG00000213977|Vega:OTTHUMG00000090701 +30968 STOML2 MIM:608292|HGNC:HGNC:14559|Ensembl:ENSG00000165283|Vega:OTTHUMG00000019851 +43847 KLK14 MIM:606135|HGNC:HGNC:6362|Ensembl:ENSG00000129437|Vega:OTTHUMG00000143721 +43849 KLK12 MIM:605539|HGNC:HGNC:6360|Ensembl:ENSG00000186474|Vega:OTTHUMG00000165806 +49854 ZBTB21 MIM:616485|HGNC:HGNC:13083|Ensembl:ENSG00000173276|Vega:OTTHUMG00000086789 +49855 SCAPER MIM:611611|HGNC:HGNC:13081|Ensembl:ENSG00000140386|Vega:OTTHUMG00000172655 +49856 WRAP73 MIM:606040|HGNC:HGNC:12759|Ensembl:ENSG00000116213|Vega:OTTHUMG00000000612 +49860 CRNN MIM:611312|HGNC:HGNC:1230|Ensembl:ENSG00000143536|Vega:OTTHUMG00000012383 +49861 CLDN20 HGNC:HGNC:2042|Ensembl:ENSG00000171217|Vega:OTTHUMG00000015882 +50484 RRM2B MIM:604712|HGNC:HGNC:17296|Ensembl:ENSG00000048392|Vega:OTTHUMG00000164776 +50485 SMARCAL1 MIM:606622|HGNC:HGNC:11102|Ensembl:ENSG00000138375|Vega:OTTHUMG00000133055 +50486 G0S2 MIM:614447|HGNC:HGNC:30229|Ensembl:ENSG00000123689|Vega:OTTHUMG00000036479 +50487 PLA2G3 MIM:611651|HGNC:HGNC:17934|Ensembl:ENSG00000100078|Vega:OTTHUMG00000151255 +50488 MINK1 MIM:609426|HGNC:HGNC:17565|Ensembl:ENSG00000141503|Vega:OTTHUMG00000177932 +50489 CD207 MIM:604862|HGNC:HGNC:17935|Ensembl:ENSG00000116031|Vega:OTTHUMG00000153176 +50506 DUOX2 MIM:606759|HGNC:HGNC:13273|Ensembl:ENSG00000140279|Vega:OTTHUMG00000131355 +50507 NOX4 MIM:605261|HGNC:HGNC:7891|Ensembl:ENSG00000086991|Vega:OTTHUMG00000167298 +50508 NOX3 MIM:607105|HGNC:HGNC:7890|Ensembl:ENSG00000074771|Vega:OTTHUMG00000015883 +50509 COL5A3 MIM:120216|HGNC:HGNC:14864|Ensembl:ENSG00000080573|Vega:OTTHUMG00000150019 +50511 SYCP3 MIM:604759|HGNC:HGNC:18130|Ensembl:ENSG00000139351|Vega:OTTHUMG00000150132 +50512 PODXL2 MIM:616627|HGNC:HGNC:17936|Ensembl:ENSG00000114631|Vega:OTTHUMG00000159642 +50514 DEC1 MIM:604767|HGNC:HGNC:23658|Ensembl:ENSG00000173077|Vega:OTTHUMG00000020549 +50515 CHST11 MIM:610128|HGNC:HGNC:17422|Ensembl:ENSG00000171310|Vega:OTTHUMG00000169803 +50516 PPP1R14BP1 HGNC:HGNC:9058 +50604 IL20 MIM:605619|HGNC:HGNC:6002|Ensembl:ENSG00000162891|Vega:OTTHUMG00000036456 +50608 IBD4 MIM:606675|HGNC:HGNC:5333 +50612 CXCL1P1 HGNC:HGNC:10641 +50613 UBQLN3 MIM:605473|HGNC:HGNC:12510|Ensembl:ENSG00000175520|Vega:OTTHUMG00000066886 +50614 GALNT9 MIM:606251|HGNC:HGNC:4131|Ensembl:ENSG00000182870|Vega:OTTHUMG00000168256 +50615 IL21R MIM:605383|HGNC:HGNC:6006|Ensembl:ENSG00000103522|Vega:OTTHUMG00000131675 +50616 IL22 MIM:605330|HGNC:HGNC:14900|Ensembl:ENSG00000127318|Vega:OTTHUMG00000169119 +50617 ATP6V0A4 MIM:605239|HGNC:HGNC:866|Ensembl:ENSG00000105929|Vega:OTTHUMG00000157122 +50618 ITSN2 MIM:604464|HGNC:HGNC:6184|Ensembl:ENSG00000198399|Vega:OTTHUMG00000090818 +50619 DEF6 MIM:610094|HGNC:HGNC:2760|Ensembl:ENSG00000023892|Vega:OTTHUMG00000014563 +50624 CUZD1 MIM:616644|HGNC:HGNC:17937|Ensembl:ENSG00000138161|Vega:OTTHUMG00000019195 +50626 CYHR1 MIM:616635|HGNC:HGNC:17806|Ensembl:ENSG00000187954|Vega:OTTHUMG00000165171 +50628 GEMIN4 MIM:606969|HGNC:HGNC:15717|Ensembl:ENSG00000179409|Vega:OTTHUMG00000177495 +50631 YBX1P1 HGNC:HGNC:8015 +50632 CALY MIM:604647|HGNC:HGNC:17938|Ensembl:ENSG00000130643|Vega:OTTHUMG00000019310 +50636 ANO7 MIM:605096|HGNC:HGNC:31677|Ensembl:ENSG00000146205|Vega:OTTHUMG00000151702 +50639 MBL3P HGNC:HGNC:2221 +50640 PNPLA8 MIM:612123|HGNC:HGNC:28900|Ensembl:ENSG00000135241|Vega:OTTHUMG00000154870 +50644 MRXS11 MIM:300238|HGNC:HGNC:13865 +50649 ARHGEF4 MIM:605216|HGNC:HGNC:684|Ensembl:ENSG00000136002|Vega:OTTHUMG00000131657 +50650 ARHGEF3 MIM:612115|HGNC:HGNC:683|Ensembl:ENSG00000163947|Vega:OTTHUMG00000158857 +50651 SLC45A1 MIM:605763|HGNC:HGNC:17939|Ensembl:ENSG00000162426|Vega:OTTHUMG00000000503 +50652 PCA3 MIM:604845|HGNC:HGNC:8637|Ensembl:ENSG00000225937 +50674 NEUROG3 MIM:604882|HGNC:HGNC:13806|Ensembl:ENSG00000122859|Vega:OTTHUMG00000018391 +50700 RDH8 MIM:608575|HGNC:HGNC:14423|Ensembl:ENSG00000080511|Vega:OTTHUMG00000180392 +50715 EJM2 MIM:604827|HGNC:HGNC:3306 +50717 DCAF8 MIM:615820|HGNC:HGNC:24891|Ensembl:ENSG00000132716|Vega:OTTHUMG00000031604 +50801 KCNK4 MIM:605720|HGNC:HGNC:6279|Ensembl:ENSG00000182450|Vega:OTTHUMG00000168006 +50802 IGK HGNC:HGNC:5715 +50804 MYEF2 HGNC:HGNC:17940|Ensembl:ENSG00000104177|Vega:OTTHUMG00000172120 +50805 IRX4 MIM:606199|HGNC:HGNC:6129|Ensembl:ENSG00000113430|Vega:OTTHUMG00000090411 +50807 ASAP1 MIM:605953|HGNC:HGNC:2720|Ensembl:ENSG00000153317|Vega:OTTHUMG00000164772 +50808 AK3 MIM:609290|HGNC:HGNC:17376|Ensembl:ENSG00000147853|Vega:OTTHUMG00000019472 +50809 HP1BP3 MIM:616072|HGNC:HGNC:24973|Ensembl:ENSG00000127483|Vega:OTTHUMG00000002622 +50810 HDGFL3 MIM:616643|HGNC:HGNC:24937|Ensembl:ENSG00000166503|Vega:OTTHUMG00000172685 +50813 COPS7A MIM:616009|HGNC:HGNC:16758|Ensembl:ENSG00000111652|Vega:OTTHUMG00000169182 +50814 NSDHL MIM:300275|HGNC:HGNC:13398|Ensembl:ENSG00000147383|Vega:OTTHUMG00000024185 +50823 HMU MIM:146550 +50829 HDPA MIM:300221 +50830 TGCT1 MIM:300228|HGNC:HGNC:13466 +50831 TAS2R3 MIM:604868|HGNC:HGNC:14910|Ensembl:ENSG00000127362|Vega:OTTHUMG00000157637 +50832 TAS2R4 MIM:604869|HGNC:HGNC:14911|Ensembl:ENSG00000127364|Vega:OTTHUMG00000157634 +50833 TAS2R16 MIM:604867|HGNC:HGNC:14921|Ensembl:ENSG00000128519|Vega:OTTHUMG00000157090 +50834 TAS2R1 MIM:604796|HGNC:HGNC:14909|Ensembl:ENSG00000169777|Vega:OTTHUMG00000090500 +50835 TAS2R9 MIM:604795|HGNC:HGNC:14917|Ensembl:ENSG00000121381|Vega:OTTHUMG00000168507 +50836 TAS2R8 MIM:604794|HGNC:HGNC:14915|Ensembl:ENSG00000121314|Vega:OTTHUMG00000168506 +50837 TAS2R7 MIM:604793|HGNC:HGNC:14913|Ensembl:ENSG00000121377|Vega:OTTHUMG00000168505 +50838 TAS2R13 MIM:604792|HGNC:HGNC:14919|Ensembl:ENSG00000212128|Vega:OTTHUMG00000168555 +50839 TAS2R10 MIM:604791|HGNC:HGNC:14918|Ensembl:ENSG00000121318|Vega:OTTHUMG00000168508 +50840 TAS2R14 MIM:604790|HGNC:HGNC:14920|Ensembl:ENSG00000212127|Vega:OTTHUMG00000162720 +50846 DHH MIM:605423|HGNC:HGNC:2865|Ensembl:ENSG00000139549|Vega:OTTHUMG00000170408 +50848 F11R MIM:605721|HGNC:HGNC:14685|Ensembl:ENSG00000158769|Vega:OTTHUMG00000028602 +50852 TRAT1 MIM:604962|HGNC:HGNC:30698|Ensembl:ENSG00000163519|Vega:OTTHUMG00000159198 +50853 VILL HGNC:HGNC:30906|Ensembl:ENSG00000136059|Vega:OTTHUMG00000130814 +50854 C6orf48 MIM:605447|HGNC:HGNC:19078|Ensembl:ENSG00000204387|Vega:OTTHUMG00000031175 +50855 PARD6A MIM:607484|HGNC:HGNC:15943|Ensembl:ENSG00000102981|Vega:OTTHUMG00000137534 +50856 CLEC4A MIM:605306|HGNC:HGNC:13257|Ensembl:ENSG00000111729|Vega:OTTHUMG00000168571 +50858 TTTY1 HGNC:HGNC:14022|Ensembl:ENSG00000129845 +50859 SPOCK3 MIM:607989|HGNC:HGNC:13565|Ensembl:ENSG00000196104|Vega:OTTHUMG00000161190 +50861 STMN3 MIM:608362|HGNC:HGNC:15926|Ensembl:ENSG00000197457|Vega:OTTHUMG00000032985 +50862 RNF141 MIM:616641|HGNC:HGNC:21159|Ensembl:ENSG00000110315|Vega:OTTHUMG00000165712 +50863 NTM MIM:607938|HGNC:HGNC:17941|Ensembl:ENSG00000182667|Vega:OTTHUMG00000066364 +50865 HEBP1 MIM:605826|HGNC:HGNC:17176|Ensembl:ENSG00000013583|Vega:OTTHUMG00000168771 +50937 CDON MIM:608707|HGNC:HGNC:17104|Ensembl:ENSG00000064309|Vega:OTTHUMG00000165862 +50939 IMPG2 MIM:607056|HGNC:HGNC:18362|Ensembl:ENSG00000081148|Vega:OTTHUMG00000159091 +50940 PDE11A MIM:604961|HGNC:HGNC:8773|Ensembl:ENSG00000128655|Vega:OTTHUMG00000154188 +50941 IBD5 MIM:606348|HGNC:HGNC:5334 +50942 IBD6 MIM:606674|HGNC:HGNC:5335 +50943 FOXP3 MIM:300292|HGNC:HGNC:6106|Ensembl:ENSG00000049768|Vega:OTTHUMG00000024135 +50944 SHANK1 MIM:604999|HGNC:HGNC:15474|Ensembl:ENSG00000161681|Vega:OTTHUMG00000137380 +50945 TBX22 MIM:300307|HGNC:HGNC:11600|Ensembl:ENSG00000122145|Vega:OTTHUMG00000021901 +50947 BHD MIM:142669 +50948 OHDS MIM:143850 +50951 MMVP1 MIM:157700|HGNC:HGNC:19144 +50952 HMN7A MIM:158580 +50960 MYMY1 MIM:252350|HGNC:HGNC:16401 +50963 BRKS1 MIM:259450 +50964 SOST MIM:605740|HGNC:HGNC:13771|Ensembl:ENSG00000167941|Vega:OTTHUMG00000180888 +50966 ECA1 MIM:600131|HGNC:HGNC:3144 +50968 FCMTE1 MIM:601068|HGNC:HGNC:37158 +50970 TSG11 MIM:603040 +50971 ENFL2 MIM:603204 +50975 TCO MIM:603386 +50976 GRD2 MIM:603388 +50979 MHW2 MIM:603664 +50982 NIDDM3 MIM:603694 +50986 HYT2 MIM:604329 +50987 FPEVF MIM:604364 +50989 HMSNO MIM:604484 +50999 TMED5 MIM:616876|HGNC:HGNC:24251|Ensembl:ENSG00000117500|Vega:OTTHUMG00000010162 +51000 SLC35B3 MIM:610845|HGNC:HGNC:21601|Ensembl:ENSG00000124786|Vega:OTTHUMG00000014224 +51001 MTERF3 MIM:616930|HGNC:HGNC:24258|Ensembl:ENSG00000156469|Vega:OTTHUMG00000164713 +51002 TPRKB MIM:608680|HGNC:HGNC:24259|Ensembl:ENSG00000144034|Vega:OTTHUMG00000129815 +51003 MED31 HGNC:HGNC:24260|Ensembl:ENSG00000108590|Vega:OTTHUMG00000102051 +51004 COQ6 MIM:614647|HGNC:HGNC:20233|Ensembl:ENSG00000119723|Vega:OTTHUMG00000171260 +51005 AMDHD2 HGNC:HGNC:24262|Ensembl:ENSG00000162066|Vega:OTTHUMG00000128866 +51006 SLC35C2 HGNC:HGNC:17117|Ensembl:ENSG00000080189|Vega:OTTHUMG00000033050 +51008 ASCC1 MIM:614215|HGNC:HGNC:24268|Ensembl:ENSG00000138303|Vega:OTTHUMG00000018434 +51009 DERL2 MIM:610304|HGNC:HGNC:17943|Ensembl:ENSG00000072849|Vega:OTTHUMG00000102040 +51010 EXOSC3 MIM:606489|HGNC:HGNC:17944|Ensembl:ENSG00000107371|Vega:OTTHUMG00000019932 +51011 FAHD2A HGNC:HGNC:24252|Ensembl:ENSG00000115042|Vega:OTTHUMG00000130397 +51012 PRELID3B HGNC:HGNC:15892|Ensembl:ENSG00000101166|Vega:OTTHUMG00000032856 +51013 EXOSC1 MIM:606493|HGNC:HGNC:17286|Ensembl:ENSG00000171311|Vega:OTTHUMG00000018854 +51014 TMED7 HGNC:HGNC:24253|Ensembl:ENSG00000134970|Vega:OTTHUMG00000132013 +51015 ISOC1 HGNC:HGNC:24254|Ensembl:ENSG00000066583|Vega:OTTHUMG00000163144 +51016 EMC9 HGNC:HGNC:20273|Ensembl:ENSG00000100908|Vega:OTTHUMG00000028796 +51018 RRP15 MIM:611193|HGNC:HGNC:24255|Ensembl:ENSG00000067533|Vega:OTTHUMG00000039494 +51019 WASHC3 HGNC:HGNC:24256|Ensembl:ENSG00000120860|Vega:OTTHUMG00000168187 +51020 HDDC2 HGNC:HGNC:21078|Ensembl:ENSG00000111906|Vega:OTTHUMG00000015506 +51021 MRPS16 MIM:609204|HGNC:HGNC:14048|Ensembl:ENSG00000182180|Vega:OTTHUMG00000018454 +51022 GLRX2 MIM:606820|HGNC:HGNC:16065|Ensembl:ENSG00000023572|Vega:OTTHUMG00000035677 +51023 MRPS18C MIM:611983|HGNC:HGNC:16633|Ensembl:ENSG00000163319|Vega:OTTHUMG00000130430 +51024 FIS1 MIM:609003|HGNC:HGNC:21689|Ensembl:ENSG00000214253|Vega:OTTHUMG00000157106 +51025 PAM16 MIM:614336|HGNC:HGNC:29679|Ensembl:ENSG00000217930|Vega:OTTHUMG00000129466 +51026 GOLT1B MIM:615078|HGNC:HGNC:20175|Ensembl:ENSG00000111711|Vega:OTTHUMG00000169133 +51027 BOLA1 MIM:613181|HGNC:HGNC:24263|Ensembl:ENSG00000178096|Vega:OTTHUMG00000012087 +51028 VPS36 MIM:610903|HGNC:HGNC:20312|Ensembl:ENSG00000136100|Vega:OTTHUMG00000016964 +51029 DESI2 MIM:614638|HGNC:HGNC:24264|Ensembl:ENSG00000121644|Vega:OTTHUMG00000040398 +51030 TVP23B HGNC:HGNC:20399|Ensembl:ENSG00000171928|Vega:OTTHUMG00000059052 +51031 GLOD4 HGNC:HGNC:14111|Ensembl:ENSG00000167699|Vega:OTTHUMG00000177497 +51032 CELA2B MIM:609444|HGNC:HGNC:29995|Ensembl:ENSG00000215704|Vega:OTTHUMG00000002259 +51035 UBXN1 MIM:616378|HGNC:HGNC:18402|Ensembl:ENSG00000162191|Vega:OTTHUMG00000167580 +51042 ZNF593 MIM:616698|HGNC:HGNC:30943|Ensembl:ENSG00000142684|Vega:OTTHUMG00000007538 +51043 ZBTB7B MIM:607646|HGNC:HGNC:18668|Ensembl:ENSG00000160685|Vega:OTTHUMG00000037414 +51046 ST8SIA3 MIM:609478|HGNC:HGNC:14269|Ensembl:ENSG00000177511|Vega:OTTHUMG00000180101 +51050 PI15 MIM:607076|HGNC:HGNC:8946|Ensembl:ENSG00000137558|Vega:OTTHUMG00000164528 +51052 PRLH MIM:602663|HGNC:HGNC:17945|Ensembl:ENSG00000071677|Vega:OTTHUMG00000133296 +51053 GMNN MIM:602842|HGNC:HGNC:17493|Ensembl:ENSG00000112312|Vega:OTTHUMG00000014363 +51054 PLEKHA8P1 HGNC:HGNC:30222|Ensembl:ENSG00000134297 +51056 LAP3 MIM:170250|HGNC:HGNC:18449|Ensembl:ENSG00000002549|Vega:OTTHUMG00000048214 +51057 WDPCP MIM:613580|HGNC:HGNC:28027|Ensembl:ENSG00000143951|Vega:OTTHUMG00000152566 +51058 ZNF691 HGNC:HGNC:28028|Ensembl:ENSG00000164011|Vega:OTTHUMG00000007623 +51059 FAM135B HGNC:HGNC:28029|Ensembl:ENSG00000147724|Vega:OTTHUMG00000149864 +51060 TXNDC12 MIM:609448|HGNC:HGNC:24626|Ensembl:ENSG00000117862|Vega:OTTHUMG00000008629 +51061 TXNDC11 HGNC:HGNC:28030|Ensembl:ENSG00000153066|Vega:OTTHUMG00000177467 +51062 ATL1 MIM:606439|HGNC:HGNC:11231|Ensembl:ENSG00000198513|Vega:OTTHUMG00000140297 +51063 CALHM2 MIM:612235|HGNC:HGNC:23493|Ensembl:ENSG00000138172|Vega:OTTHUMG00000018990 +51065 RPS27L MIM:612055|HGNC:HGNC:18476|Ensembl:ENSG00000185088|Vega:OTTHUMG00000155301 +51066 SSUH2 MIM:617479|HGNC:HGNC:24809|Ensembl:ENSG00000125046|Vega:OTTHUMG00000122075 +51067 YARS2 MIM:610957|HGNC:HGNC:24249|Ensembl:ENSG00000139131|Vega:OTTHUMG00000169454 +51068 NMD3 MIM:611021|HGNC:HGNC:24250|Ensembl:ENSG00000169251|Vega:OTTHUMG00000159063 +51069 MRPL2 MIM:611822|HGNC:HGNC:14056|Ensembl:ENSG00000112651|Vega:OTTHUMG00000014719 +51070 NOSIP MIM:616759|HGNC:HGNC:17946|Ensembl:ENSG00000142546|Vega:OTTHUMG00000183169 +51071 DERA HGNC:HGNC:24269|Ensembl:ENSG00000023697|Vega:OTTHUMG00000165537 +51072 MEMO1 MIM:611786|HGNC:HGNC:14014|Ensembl:ENSG00000162959|Vega:OTTHUMG00000128453 +51073 MRPL4 MIM:611823|HGNC:HGNC:14276|Ensembl:ENSG00000105364|Vega:OTTHUMG00000180400 +51074 APIP MIM:612491|HGNC:HGNC:17581|Ensembl:ENSG00000149089|Vega:OTTHUMG00000166455 +51075 TMX2 MIM:616715|HGNC:HGNC:30739|Ensembl:ENSG00000213593|Vega:OTTHUMG00000167200 +51076 CUTC MIM:610101|HGNC:HGNC:24271|Ensembl:ENSG00000119929|Vega:OTTHUMG00000018889 +51077 FCF1 HGNC:HGNC:20220|Ensembl:ENSG00000119616|Vega:OTTHUMG00000171480 +51078 THAP4 MIM:612533|HGNC:HGNC:23187|Ensembl:ENSG00000176946|Vega:OTTHUMG00000133410 +51079 NDUFA13 MIM:609435|HGNC:HGNC:17194|Ensembl:ENSG00000186010|Vega:OTTHUMG00000162211 +51081 MRPS7 MIM:611974|HGNC:HGNC:14499|Ensembl:ENSG00000125445|Vega:OTTHUMG00000179484 +51082 POLR1D MIM:613715|HGNC:HGNC:20422|Ensembl:ENSG00000186184|Vega:OTTHUMG00000016635 +51083 GAL MIM:137035|HGNC:HGNC:4114|Ensembl:ENSG00000069482|Vega:OTTHUMG00000167890 +51084 CRYL1 MIM:609877|HGNC:HGNC:18246|Ensembl:ENSG00000165475|Vega:OTTHUMG00000016516 +51085 MLXIPL MIM:605678|HGNC:HGNC:12744|Ensembl:ENSG00000009950|Vega:OTTHUMG00000129995 +51086 TNNI3K MIM:613932|HGNC:HGNC:19661|Ensembl:ENSG00000116783|Vega:OTTHUMG00000171318 +51087 YBX2 MIM:611447|HGNC:HGNC:17948|Ensembl:ENSG00000006047|Vega:OTTHUMG00000177992 +51088 KLHL5 MIM:608064|HGNC:HGNC:6356|Ensembl:ENSG00000109790|Vega:OTTHUMG00000097819 +51090 PLLP MIM:600340|HGNC:HGNC:18553|Ensembl:ENSG00000102934|Vega:OTTHUMG00000133465 +51091 SEPSECS MIM:613009|HGNC:HGNC:30605|Ensembl:ENSG00000109618|Vega:OTTHUMG00000128563 +51092 SIDT2 MIM:617551|HGNC:HGNC:24272|Ensembl:ENSG00000149577|Vega:OTTHUMG00000167065 +51093 RRNAD1 HGNC:HGNC:24273|Ensembl:ENSG00000143303|Vega:OTTHUMG00000041302 +51094 ADIPOR1 MIM:607945|HGNC:HGNC:24040|Ensembl:ENSG00000159346|Vega:OTTHUMG00000041391 +51095 TRNT1 MIM:612907|HGNC:HGNC:17341|Ensembl:ENSG00000072756|Vega:OTTHUMG00000090259 +51096 UTP18 MIM:612816|HGNC:HGNC:24274|Ensembl:ENSG00000011260|Vega:OTTHUMG00000162370 +51097 SCCPDH HGNC:HGNC:24275|Ensembl:ENSG00000143653|Vega:OTTHUMG00000040221 +51098 IFT52 MIM:617094|HGNC:HGNC:15901|Ensembl:ENSG00000101052|Vega:OTTHUMG00000032513 +51099 ABHD5 MIM:604780|HGNC:HGNC:21396|Ensembl:ENSG00000011198|Vega:OTTHUMG00000133039 +51100 SH3GLB1 MIM:609287|HGNC:HGNC:10833|Ensembl:ENSG00000097033|Vega:OTTHUMG00000010257 +51101 ZC2HC1A HGNC:HGNC:24277|Ensembl:ENSG00000104427|Vega:OTTHUMG00000164619 +51102 MECR MIM:608205|HGNC:HGNC:19691|Ensembl:ENSG00000116353|Vega:OTTHUMG00000059082 +51103 NDUFAF1 MIM:606934|HGNC:HGNC:18828|Ensembl:ENSG00000137806|Vega:OTTHUMG00000130340 +51104 ABHD17B HGNC:HGNC:24278|Ensembl:ENSG00000107362|Vega:OTTHUMG00000020001 +51105 PHF20L1 HGNC:HGNC:24280|Ensembl:ENSG00000129292|Vega:OTTHUMG00000148656 +51106 TFB1M MIM:607033|HGNC:HGNC:17037|Ensembl:ENSG00000029639|Vega:OTTHUMG00000015881 +51107 APH1A MIM:607629|HGNC:HGNC:29509|Ensembl:ENSG00000117362|Vega:OTTHUMG00000012545 +51108 METTL9 MIM:609388|HGNC:HGNC:24586|Ensembl:ENSG00000197006|Vega:OTTHUMG00000131584 +51109 RDH11 MIM:607849|HGNC:HGNC:17964|Ensembl:ENSG00000072042|Vega:OTTHUMG00000171196 +51110 LACTB2 HGNC:HGNC:18512|Ensembl:ENSG00000147592|Vega:OTTHUMG00000164430 +51111 KMT5B MIM:610881|HGNC:HGNC:24283|Ensembl:ENSG00000110066|Vega:OTTHUMG00000150484 +51112 TRAPPC12 MIM:614139|HGNC:HGNC:24284|Ensembl:ENSG00000171853|Vega:OTTHUMG00000090328 +51114 ZDHHC9 MIM:300646|HGNC:HGNC:18475|Ensembl:ENSG00000188706|Vega:OTTHUMG00000022375 +51115 RMDN1 MIM:611871|HGNC:HGNC:24285|Ensembl:ENSG00000176623|Vega:OTTHUMG00000163692 +51116 MRPS2 MIM:611971|HGNC:HGNC:14495|Ensembl:ENSG00000122140|Vega:OTTHUMG00000020910 +51117 COQ4 MIM:612898|HGNC:HGNC:19693|Ensembl:ENSG00000167113|Vega:OTTHUMG00000020743 +51118 UTP11 MIM:609440|HGNC:HGNC:24329|Ensembl:ENSG00000183520|Vega:OTTHUMG00000004435 +51119 SBDS MIM:607444|HGNC:HGNC:19440|Ensembl:ENSG00000126524|Vega:OTTHUMG00000023165 +51121 RPL26L1 HGNC:HGNC:17050|Ensembl:ENSG00000037241|Vega:OTTHUMG00000130517 +51122 COMMD2 MIM:616699|HGNC:HGNC:24993|Ensembl:ENSG00000114744|Vega:OTTHUMG00000159616 +51123 ZNF706 HGNC:HGNC:24992|Ensembl:ENSG00000120963|Vega:OTTHUMG00000164823 +51124 IER3IP1 MIM:609382|HGNC:HGNC:18550|Ensembl:ENSG00000134049|Ensembl:ENSG00000267228|Vega:OTTHUMG00000132650|Vega:OTTHUMG00000180304 +51125 GOLGA7 MIM:609453|HGNC:HGNC:24876|Ensembl:ENSG00000147533|Vega:OTTHUMG00000164077 +51126 NAA20 MIM:610833|HGNC:HGNC:15908|Ensembl:ENSG00000173418|Vega:OTTHUMG00000031998 +51127 TRIM17 MIM:606123|HGNC:HGNC:13430|Ensembl:ENSG00000162931|Vega:OTTHUMG00000039974 +51128 SAR1B MIM:607690|HGNC:HGNC:10535|Ensembl:ENSG00000152700|Vega:OTTHUMG00000129114 +51129 ANGPTL4 MIM:605910|HGNC:HGNC:16039|Ensembl:ENSG00000167772|Vega:OTTHUMG00000182273 +51130 ASB3 MIM:605760|HGNC:HGNC:16013|Ensembl:ENSG00000115239|Vega:OTTHUMG00000184778 +51131 PHF11 MIM:607796|HGNC:HGNC:17024|Ensembl:ENSG00000136147|Vega:OTTHUMG00000016916 +51132 RLIM MIM:300379|HGNC:HGNC:13429|Ensembl:ENSG00000131263|Vega:OTTHUMG00000021859 +51133 KCTD3 MIM:613272|HGNC:HGNC:21305|Ensembl:ENSG00000136636|Vega:OTTHUMG00000037019 +51134 CEP83 MIM:615847|HGNC:HGNC:17966|Ensembl:ENSG00000173588|Vega:OTTHUMG00000170242 +51135 IRAK4 MIM:606883|HGNC:HGNC:17967|Ensembl:ENSG00000198001|Vega:OTTHUMG00000169425 +51136 RNFT1 MIM:615172|HGNC:HGNC:30206|Ensembl:ENSG00000189050|Vega:OTTHUMG00000148658 +51138 COPS4 MIM:616008|HGNC:HGNC:16702|Ensembl:ENSG00000138663|Vega:OTTHUMG00000130298 +51141 INSIG2 MIM:608660|HGNC:HGNC:20452|Ensembl:ENSG00000125629|Vega:OTTHUMG00000058518 +51142 CHCHD2 MIM:616244|HGNC:HGNC:21645|Ensembl:ENSG00000106153|Vega:OTTHUMG00000129429 +51143 DYNC1LI1 MIM:615890|HGNC:HGNC:18745|Ensembl:ENSG00000144635|Vega:OTTHUMG00000130750 +51144 HSD17B12 MIM:609574|HGNC:HGNC:18646|Ensembl:ENSG00000149084|Vega:OTTHUMG00000166403 +51145 LOC51145 - +51146 A4GNT MIM:616709|HGNC:HGNC:17968|Ensembl:ENSG00000118017|Vega:OTTHUMG00000159820 +51147 ING4 MIM:608524|HGNC:HGNC:19423|Ensembl:ENSG00000111653|Vega:OTTHUMG00000141274 +51148 CERCAM MIM:616626|HGNC:HGNC:23723|Ensembl:ENSG00000167123|Vega:OTTHUMG00000020747 +51149 MRNIP MIM:617154|HGNC:HGNC:30817|Ensembl:ENSG00000161010|Vega:OTTHUMG00000163490 +51150 SDF4 MIM:614282|HGNC:HGNC:24188|Ensembl:ENSG00000078808|Vega:OTTHUMG00000001812 +51151 SLC45A2 MIM:606202|HGNC:HGNC:16472|Ensembl:ENSG00000164175|Vega:OTTHUMG00000090719 +51152 LINC00328 HGNC:HGNC:42028 +51154 MRTO4 HGNC:HGNC:18477|Ensembl:ENSG00000053372|Vega:OTTHUMG00000002496 +51155 JPT1 HGNC:HGNC:14569|Ensembl:ENSG00000189159|Vega:OTTHUMG00000154521 +51156 SERPINA10 MIM:605271|HGNC:HGNC:15996|Ensembl:ENSG00000140093|Vega:OTTHUMG00000171345 +51157 ZNF580 HGNC:HGNC:29473|Ensembl:ENSG00000213015|Vega:OTTHUMG00000180868 +51160 VPS28 MIM:611952|HGNC:HGNC:18178|Ensembl:ENSG00000160948|Vega:OTTHUMG00000165209 +51161 C3orf18 HGNC:HGNC:24837|Ensembl:ENSG00000088543|Vega:OTTHUMG00000156854 +51162 EGFL7 MIM:608582|HGNC:HGNC:20594|Ensembl:ENSG00000172889|Vega:OTTHUMG00000020938 +51163 DBR1 MIM:607024|HGNC:HGNC:15594|Ensembl:ENSG00000138231|Vega:OTTHUMG00000159824 +51164 DCTN4 MIM:614758|HGNC:HGNC:15518|Ensembl:ENSG00000132912|Vega:OTTHUMG00000130079 +51166 AADAT MIM:611754|HGNC:HGNC:17929|Ensembl:ENSG00000109576|Vega:OTTHUMG00000160912 +51167 CYB5R4 MIM:608343|HGNC:HGNC:20147|Ensembl:ENSG00000065615|Vega:OTTHUMG00000015118 +51168 MYO15A MIM:602666|HGNC:HGNC:7594|Ensembl:ENSG00000091536|Vega:OTTHUMG00000059390 +51170 HSD17B11 MIM:612831|HGNC:HGNC:22960|Ensembl:ENSG00000198189|Vega:OTTHUMG00000130594 +51171 HSD17B14 MIM:612832|HGNC:HGNC:23238|Ensembl:ENSG00000087076|Vega:OTTHUMG00000183328 +51172 NAGPA MIM:607985|HGNC:HGNC:17378|Ensembl:ENSG00000103174|Vega:OTTHUMG00000090515 +51174 TUBD1 MIM:607344|HGNC:HGNC:16811|Ensembl:ENSG00000108423|Vega:OTTHUMG00000179885 +51175 TUBE1 MIM:607345|HGNC:HGNC:20775|Ensembl:ENSG00000074935|Vega:OTTHUMG00000015382 +51176 LEF1 MIM:153245|HGNC:HGNC:6551|Ensembl:ENSG00000138795|Vega:OTTHUMG00000131809 +51177 PLEKHO1 MIM:608335|HGNC:HGNC:24310|Ensembl:ENSG00000023902|Vega:OTTHUMG00000012510 +51179 HAO2 MIM:605176|HGNC:HGNC:4810|Ensembl:ENSG00000116882|Vega:OTTHUMG00000012410 +51181 DCXR MIM:608347|HGNC:HGNC:18985|Ensembl:ENSG00000169738|Vega:OTTHUMG00000178483 +51182 HSPA14 MIM:610369|HGNC:HGNC:29526|Ensembl:ENSG00000187522|Vega:OTTHUMG00000191882 +51184 GPN3 HGNC:HGNC:30186|Ensembl:ENSG00000111231|Vega:OTTHUMG00000169524 +51185 CRBN MIM:609262|HGNC:HGNC:30185|Ensembl:ENSG00000113851|Vega:OTTHUMG00000090261 +51186 TCEAL9 HGNC:HGNC:30084|Ensembl:ENSG00000185222|Vega:OTTHUMG00000022097 +51187 RSL24D1 MIM:613262|HGNC:HGNC:18479|Ensembl:ENSG00000137876|Vega:OTTHUMG00000131957 +51188 SS18L2 MIM:606473|HGNC:HGNC:15593|Ensembl:ENSG00000008324|Vega:OTTHUMG00000131794 +51191 HERC5 MIM:608242|HGNC:HGNC:24368|Ensembl:ENSG00000138646|Vega:OTTHUMG00000130953 +51192 CKLF MIM:616074|HGNC:HGNC:13253|Ensembl:ENSG00000217555|Vega:OTTHUMG00000137504 +51193 ZNF639 HGNC:HGNC:30950|Ensembl:ENSG00000121864|Vega:OTTHUMG00000157439 +51194 IPO11 MIM:610889|HGNC:HGNC:20628|Ensembl:ENSG00000086200|Vega:OTTHUMG00000154400 +51195 RAPGEFL1 HGNC:HGNC:17428|Ensembl:ENSG00000108352|Vega:OTTHUMG00000133325 +51196 PLCE1 MIM:608414|HGNC:HGNC:17175|Ensembl:ENSG00000138193|Vega:OTTHUMG00000018789 +51198 CDKN2A-AS1 HGNC:HGNC:23831 +51199 NIN MIM:608684|HGNC:HGNC:14906|Ensembl:ENSG00000100503|Vega:OTTHUMG00000029569 +51200 CPA4 MIM:607635|HGNC:HGNC:15740|Ensembl:ENSG00000128510|Vega:OTTHUMG00000157825 +51201 ZDHHC2 HGNC:HGNC:18469|Ensembl:ENSG00000104219|Vega:OTTHUMG00000163860 +51202 DDX47 MIM:615428|HGNC:HGNC:18682|Ensembl:ENSG00000213782|Vega:OTTHUMG00000168709 +51203 NUSAP1 MIM:612818|HGNC:HGNC:18538|Ensembl:ENSG00000137804|Vega:OTTHUMG00000172588 +51204 TACO1 MIM:612958|HGNC:HGNC:24316|Ensembl:ENSG00000136463|Vega:OTTHUMG00000178904 +51205 ACP6 MIM:611471|HGNC:HGNC:29609|Ensembl:ENSG00000162836|Vega:OTTHUMG00000014019 +51206 GP6 MIM:605546|HGNC:HGNC:14388|Ensembl:ENSG00000088053|Vega:OTTHUMG00000159709 +51207 DUSP13 MIM:613191|HGNC:HGNC:19681|Ensembl:ENSG00000079393|Vega:OTTHUMG00000018516 +51208 CLDN18 MIM:609210|HGNC:HGNC:2039|Ensembl:ENSG00000066405|Vega:OTTHUMG00000159762 +51209 RAB9B MIM:300285|HGNC:HGNC:14090|Ensembl:ENSG00000123570|Vega:OTTHUMG00000022112 +51213 LUZP4 MIM:300616|HGNC:HGNC:24971|Ensembl:ENSG00000102021|Vega:OTTHUMG00000022234 +51214 IGF2-AS MIM:610146|HGNC:HGNC:14062|Ensembl:ENSG00000099869 +51218 GLRX5 MIM:609588|HGNC:HGNC:20134|Ensembl:ENSG00000182512|Vega:OTTHUMG00000171636 +51222 ZNF219 MIM:605036|HGNC:HGNC:13011|Ensembl:ENSG00000165804|Vega:OTTHUMG00000029647 +51224 ELOA2 MIM:609522|HGNC:HGNC:30771|Ensembl:ENSG00000206181|Vega:OTTHUMG00000132649 +51225 ABI3 MIM:606363|HGNC:HGNC:29859|Ensembl:ENSG00000108798|Vega:OTTHUMG00000161306 +51226 COPZ2 MIM:615526|HGNC:HGNC:19356|Ensembl:ENSG00000005243|Vega:OTTHUMG00000178684 +51227 PIGP MIM:605938|HGNC:HGNC:3046|Ensembl:ENSG00000185808|Vega:OTTHUMG00000086653 +51228 GLTP MIM:608949|HGNC:HGNC:24867|Ensembl:ENSG00000139433|Vega:OTTHUMG00000169278 +51230 PHF20 MIM:610335|HGNC:HGNC:16098|Ensembl:ENSG00000025293|Vega:OTTHUMG00000032367 +51231 VRK3 HGNC:HGNC:18996|Ensembl:ENSG00000105053|Vega:OTTHUMG00000183053 +51232 CRIM1 MIM:606189|HGNC:HGNC:2359|Ensembl:ENSG00000150938|Vega:OTTHUMG00000099419 +51233 DRICH1 HGNC:HGNC:28031|Ensembl:ENSG00000189269|Vega:OTTHUMG00000186352 +51234 EMC4 MIM:616245|HGNC:HGNC:28032|Ensembl:ENSG00000128463|Vega:OTTHUMG00000129411 +51236 HGH1 HGNC:HGNC:24161|Ensembl:ENSG00000235173|Vega:OTTHUMG00000165246 +51237 MZB1 MIM:609447|HGNC:HGNC:30125|Ensembl:ENSG00000170476|Vega:OTTHUMG00000163390 +51239 ANKRD39 HGNC:HGNC:28640|Ensembl:ENSG00000213337|Vega:OTTHUMG00000130530 +51241 COX16 HGNC:HGNC:20213|Ensembl:ENSG00000133983|Vega:OTTHUMG00000171238 +51244 CCDC174 MIM:616735|HGNC:HGNC:28033|Ensembl:ENSG00000154781|Vega:OTTHUMG00000129837 +51246 SHISA5 MIM:607290|HGNC:HGNC:30376|Ensembl:ENSG00000164054|Vega:OTTHUMG00000133529 +51247 PAIP2 MIM:605604|HGNC:HGNC:17970|Ensembl:ENSG00000120727|Vega:OTTHUMG00000129227 +51248 PDZD11 MIM:300632|HGNC:HGNC:28034|Ensembl:ENSG00000120509|Vega:OTTHUMG00000021771 +51249 TMEM69 HGNC:HGNC:28035|Ensembl:ENSG00000159596|Vega:OTTHUMG00000040993 +51250 C6orf203 HGNC:HGNC:17971|Ensembl:ENSG00000130349|Vega:OTTHUMG00000015307 +51251 NT5C3A MIM:606224|HGNC:HGNC:17820|Ensembl:ENSG00000122643|Vega:OTTHUMG00000152983 +51252 FAM178B HGNC:HGNC:28036|Ensembl:ENSG00000168754|Vega:OTTHUMG00000155257 +51253 MRPL37 MIM:611843|HGNC:HGNC:14034|Ensembl:ENSG00000116221|Vega:OTTHUMG00000008118 +51255 RNF181 MIM:612490|HGNC:HGNC:28037|Ensembl:ENSG00000168894|Vega:OTTHUMG00000130182 +51256 TBC1D7 MIM:612655|HGNC:HGNC:21066|Ensembl:ENSG00000145979|Vega:OTTHUMG00000014272 +51257 MARCH2 MIM:613332|HGNC:HGNC:28038|Ensembl:ENSG00000099785|Vega:OTTHUMG00000182282 +51258 MRPL51 MIM:611855|HGNC:HGNC:14044|Ensembl:ENSG00000111639|Vega:OTTHUMG00000168512 +51259 TMEM216 MIM:613277|HGNC:HGNC:25018|Ensembl:ENSG00000187049|Vega:OTTHUMG00000168146 +51260 PBDC1 HGNC:HGNC:28790|Ensembl:ENSG00000102390|Vega:OTTHUMG00000021876 +51263 MRPL30 MIM:611838|HGNC:HGNC:14036|Ensembl:ENSG00000185414|Ensembl:ENSG00000241962|Vega:OTTHUMG00000130642|Vega:OTTHUMG00000186049 +51264 MRPL27 MIM:611837|HGNC:HGNC:14483|Ensembl:ENSG00000108826|Vega:OTTHUMG00000162062 +51265 CDKL3 MIM:608459|HGNC:HGNC:15483|Ensembl:ENSG00000006837|Vega:OTTHUMG00000186341 +51266 CLEC1B MIM:606783|HGNC:HGNC:24356|Ensembl:ENSG00000165682|Vega:OTTHUMG00000168502 +51267 CLEC1A MIM:606782|HGNC:HGNC:24355|Ensembl:ENSG00000150048|Vega:OTTHUMG00000168504 +51268 PIPOX MIM:616713|HGNC:HGNC:17804|Ensembl:ENSG00000179761|Vega:OTTHUMG00000132679 +51270 TFDP3 MIM:300772|HGNC:HGNC:24603|Ensembl:ENSG00000183434|Vega:OTTHUMG00000022433 +51271 UBAP1 MIM:609787|HGNC:HGNC:12461|Ensembl:ENSG00000165006|Vega:OTTHUMG00000000430 +51272 BET1L MIM:615417|HGNC:HGNC:19348|Ensembl:ENSG00000177951|Vega:OTTHUMG00000119071 +51274 KLF3 MIM:609392|HGNC:HGNC:16516|Ensembl:ENSG00000109787|Vega:OTTHUMG00000097821 +51275 MAPKAPK5-AS1 HGNC:HGNC:24091|Ensembl:ENSG00000234608 +51276 ZNF571 HGNC:HGNC:25000|Ensembl:ENSG00000180479|Vega:OTTHUMG00000182016 +51277 DNAJC27 MIM:613527|HGNC:HGNC:30290|Ensembl:ENSG00000115137|Vega:OTTHUMG00000125524 +51278 IER5 MIM:607177|HGNC:HGNC:5393|Ensembl:ENSG00000162783|Vega:OTTHUMG00000035178 +51279 C1RL MIM:608974|HGNC:HGNC:21265|Ensembl:ENSG00000139178|Vega:OTTHUMG00000168144 +51280 GOLM1 MIM:606804|HGNC:HGNC:15451|Ensembl:ENSG00000135052|Vega:OTTHUMG00000020130 +51281 ANKMY1 HGNC:HGNC:20987|Ensembl:ENSG00000144504|Vega:OTTHUMG00000133355 +51282 SCAND1 MIM:610416|HGNC:HGNC:10566|Ensembl:ENSG00000171222|Vega:OTTHUMG00000032370 +51283 BFAR HGNC:HGNC:17613|Ensembl:ENSG00000103429|Vega:OTTHUMG00000129848 +51284 TLR7 MIM:300365|HGNC:HGNC:15631|Ensembl:ENSG00000196664|Vega:OTTHUMG00000021137 +51285 RASL12 HGNC:HGNC:30289|Ensembl:ENSG00000103710|Vega:OTTHUMG00000133115 +51286 CEND1 MIM:608213|HGNC:HGNC:24153|Ensembl:ENSG00000184524|Vega:OTTHUMG00000133308 +51287 COA4 MIM:608016|HGNC:HGNC:24604|Ensembl:ENSG00000181924|Vega:OTTHUMG00000168061 +51289 RXFP3 MIM:609445|HGNC:HGNC:24883|Ensembl:ENSG00000182631|Vega:OTTHUMG00000090685 +51290 ERGIC2 MIM:612236|HGNC:HGNC:30208|Ensembl:ENSG00000087502|Vega:OTTHUMG00000169322 +51291 GMIP MIM:609694|HGNC:HGNC:24852|Ensembl:ENSG00000089639|Vega:OTTHUMG00000182329 +51292 GMPR2 MIM:610781|HGNC:HGNC:4377|Ensembl:ENSG00000100938|Vega:OTTHUMG00000171912 +51293 CD320 MIM:606475|HGNC:HGNC:16692|Ensembl:ENSG00000167775|Vega:OTTHUMG00000182457 +51294 PCDH12 MIM:605622|HGNC:HGNC:8657|Ensembl:ENSG00000113555|Vega:OTTHUMG00000129658 +51295 ECSIT MIM:608388|HGNC:HGNC:29548|Ensembl:ENSG00000130159|Vega:OTTHUMG00000178590 +51296 SLC15A3 MIM:610408|HGNC:HGNC:18068|Ensembl:ENSG00000110446|Vega:OTTHUMG00000167804 +51297 BPIFA1 MIM:607412|HGNC:HGNC:15749|Ensembl:ENSG00000198183|Vega:OTTHUMG00000032243 +51298 THEG MIM:609503|HGNC:HGNC:13706|Ensembl:ENSG00000105549|Vega:OTTHUMG00000165491 +51299 NRN1 MIM:607409|HGNC:HGNC:17972|Ensembl:ENSG00000124785|Vega:OTTHUMG00000014184 +51300 TIMMDC1 MIM:615534|HGNC:HGNC:1321|Ensembl:ENSG00000113845|Vega:OTTHUMG00000159388 +51301 GCNT4 MIM:616782|HGNC:HGNC:17973|Ensembl:ENSG00000176928|Vega:OTTHUMG00000131272 +51302 CYP39A1 MIM:605994|HGNC:HGNC:17449|Ensembl:ENSG00000146233|Vega:OTTHUMG00000014785 +51303 FKBP11 MIM:610571|HGNC:HGNC:18624|Ensembl:ENSG00000134285|Vega:OTTHUMG00000170402 +51304 ZDHHC3 MIM:617150|HGNC:HGNC:18470|Ensembl:ENSG00000163812|Vega:OTTHUMG00000133093 +51305 KCNK9 MIM:605874|HGNC:HGNC:6283|Ensembl:ENSG00000169427|Vega:OTTHUMG00000164186 +51306 FAM13B MIM:609371|HGNC:HGNC:1335|Ensembl:ENSG00000031003|Vega:OTTHUMG00000129202 +51307 FAM53C MIM:609372|HGNC:HGNC:1336|Ensembl:ENSG00000120709|Vega:OTTHUMG00000129201 +51308 REEP2 MIM:609347|HGNC:HGNC:17975|Ensembl:ENSG00000132563|Vega:OTTHUMG00000129205 +51309 ARMCX1 MIM:300362|HGNC:HGNC:18073|Ensembl:ENSG00000126947|Vega:OTTHUMG00000022033 +51310 SLC22A17 MIM:611461|HGNC:HGNC:23095|Ensembl:ENSG00000092096|Vega:OTTHUMG00000028740 +51311 TLR8 MIM:300366|HGNC:HGNC:15632|Ensembl:ENSG00000101916|Vega:OTTHUMG00000021145 +51312 SLC25A37 MIM:610387|HGNC:HGNC:29786|Ensembl:ENSG00000147454|Vega:OTTHUMG00000163865 +51313 FAM198B HGNC:HGNC:25312|Ensembl:ENSG00000164125|Vega:OTTHUMG00000161537 +51314 NME8 MIM:607421|HGNC:HGNC:16473|Ensembl:ENSG00000086288|Vega:OTTHUMG00000023716 +51315 KRCC1 HGNC:HGNC:28039|Ensembl:ENSG00000172086|Vega:OTTHUMG00000130315 +51316 PLAC8 MIM:607515|HGNC:HGNC:19254|Ensembl:ENSG00000145287|Vega:OTTHUMG00000130294 +51317 PHF21A MIM:608325|HGNC:HGNC:24156|Ensembl:ENSG00000135365|Vega:OTTHUMG00000167038 +51318 MRPL35 MIM:611841|HGNC:HGNC:14489|Ensembl:ENSG00000132313|Vega:OTTHUMG00000037385 +51319 RSRC1 MIM:613352|HGNC:HGNC:24152|Ensembl:ENSG00000174891|Vega:OTTHUMG00000158758 +51320 MEX3C MIM:611005|HGNC:HGNC:28040|Ensembl:ENSG00000176624|Vega:OTTHUMG00000132693 +51321 AMZ2 MIM:615169|HGNC:HGNC:28041|Ensembl:ENSG00000196704|Vega:OTTHUMG00000179802 +51322 WAC MIM:615049|HGNC:HGNC:17327|Ensembl:ENSG00000095787|Vega:OTTHUMG00000017872 +51324 SPG21 MIM:608181|HGNC:HGNC:20373|Ensembl:ENSG00000090487|Vega:OTTHUMG00000133098 +51326 ARL17A HGNC:HGNC:24096|Ensembl:ENSG00000185829|Vega:OTTHUMG00000132817 +51327 AHSP MIM:605821|HGNC:HGNC:18075|Ensembl:ENSG00000169877|Vega:OTTHUMG00000132461 +51329 ARL6IP4 MIM:607668|HGNC:HGNC:18076|Ensembl:ENSG00000182196|Vega:OTTHUMG00000168779 +51330 TNFRSF12A MIM:605914|HGNC:HGNC:18152|Ensembl:ENSG00000006327|Vega:OTTHUMG00000129001 +51332 SPTBN5 MIM:605916|HGNC:HGNC:15680|Ensembl:ENSG00000137877|Vega:OTTHUMG00000172720 +51333 ZNF771 HGNC:HGNC:29653|Ensembl:ENSG00000179965|Vega:OTTHUMG00000176985 +51334 PRR16 MIM:615931|HGNC:HGNC:29654|Ensembl:ENSG00000184838|Vega:OTTHUMG00000128903 +51335 NGRN MIM:616718|HGNC:HGNC:18077|Ensembl:ENSG00000182768|Vega:OTTHUMG00000149807 +51337 THEM6 HGNC:HGNC:29656|Ensembl:ENSG00000130193|Vega:OTTHUMG00000164673 +51338 MS4A4A MIM:606547|HGNC:HGNC:13371|Ensembl:ENSG00000110079|Vega:OTTHUMG00000154949 +51339 DACT1 MIM:607861|HGNC:HGNC:17748|Ensembl:ENSG00000165617|Vega:OTTHUMG00000140324 +51340 CRNKL1 MIM:610952|HGNC:HGNC:15762|Ensembl:ENSG00000101343|Vega:OTTHUMG00000032000 +51341 ZBTB7A MIM:605878|HGNC:HGNC:18078|Ensembl:ENSG00000178951|Vega:OTTHUMG00000181792 +51343 FZR1 MIM:603619|HGNC:HGNC:24824|Ensembl:ENSG00000105325|Vega:OTTHUMG00000180747 +51347 TAOK3 MIM:616711|HGNC:HGNC:18133|Ensembl:ENSG00000135090|Vega:OTTHUMG00000168875 +51348 KLRF1 MIM:605029|HGNC:HGNC:13342|Ensembl:ENSG00000150045|Vega:OTTHUMG00000168391 +51350 KRT76 MIM:616671|HGNC:HGNC:24430|Ensembl:ENSG00000185069|Vega:OTTHUMG00000169797 +51351 ZNF117 MIM:194624|HGNC:HGNC:12897|Ensembl:ENSG00000152926|Vega:OTTHUMG00000156631 +51352 WT1-AS MIM:607899|HGNC:HGNC:18135|Ensembl:ENSG00000183242 +51359 ERVH-4 HGNC:HGNC:21344 +51360 MBTPS2 MIM:300294|HGNC:HGNC:15455|Ensembl:ENSG00000012174|Vega:OTTHUMG00000021237 +51361 HOOK1 MIM:607820|HGNC:HGNC:19884|Ensembl:ENSG00000134709|Vega:OTTHUMG00000008990 +51362 CDC40 MIM:605585|HGNC:HGNC:17350|Ensembl:ENSG00000168438|Vega:OTTHUMG00000015358 +51363 CHST15 MIM:608277|HGNC:HGNC:18137|Ensembl:ENSG00000182022|Vega:OTTHUMG00000019208 +51364 ZMYND10 MIM:607070|HGNC:HGNC:19412|Ensembl:ENSG00000004838|Vega:OTTHUMG00000156874 +51365 PLA1A MIM:607460|HGNC:HGNC:17661|Ensembl:ENSG00000144837|Vega:OTTHUMG00000159425 +51366 UBR5 MIM:608413|HGNC:HGNC:16806|Ensembl:ENSG00000104517|Vega:OTTHUMG00000164755 +51367 POP5 MIM:609992|HGNC:HGNC:17689|Ensembl:ENSG00000167272|Vega:OTTHUMG00000169023 +51368 TEX264 HGNC:HGNC:30247|Ensembl:ENSG00000164081|Vega:OTTHUMG00000156901 +51371 POMP MIM:613386|HGNC:HGNC:20330|Ensembl:ENSG00000132963|Vega:OTTHUMG00000016652 +51372 TMA7 MIM:615808|HGNC:HGNC:26932|Ensembl:ENSG00000232112|Vega:OTTHUMG00000156588 +51373 MRPS17 MIM:611980|HGNC:HGNC:14047|Ensembl:ENSG00000239789|Vega:OTTHUMG00000023153 +51374 ATRAID HGNC:HGNC:24090|Ensembl:ENSG00000138085|Vega:OTTHUMG00000128405 +51375 SNX7 MIM:614904|HGNC:HGNC:14971|Ensembl:ENSG00000162627|Vega:OTTHUMG00000010723 +51377 UCHL5 MIM:610667|HGNC:HGNC:19678|Ensembl:ENSG00000116750|Vega:OTTHUMG00000035561 +51378 ANGPT4 MIM:603705|HGNC:HGNC:487|Ensembl:ENSG00000101280|Vega:OTTHUMG00000031652 +51379 CRLF3 MIM:614853|HGNC:HGNC:17177|Ensembl:ENSG00000176390|Vega:OTTHUMG00000179005 +51380 CSAD MIM:616569|HGNC:HGNC:18966|Ensembl:ENSG00000139631|Vega:OTTHUMG00000048076 +51382 ATP6V1D MIM:609398|HGNC:HGNC:13527|Ensembl:ENSG00000100554|Vega:OTTHUMG00000171244 +51384 WNT16 MIM:606267|HGNC:HGNC:16267|Ensembl:ENSG00000002745|Vega:OTTHUMG00000156963 +51385 ZNF589 MIM:616702|HGNC:HGNC:16747|Ensembl:ENSG00000164048|Vega:OTTHUMG00000156833 +51386 EIF3L HGNC:HGNC:18138|Ensembl:ENSG00000100129|Vega:OTTHUMG00000150671 +51388 NIP7 HGNC:HGNC:24328|Ensembl:ENSG00000132603|Vega:OTTHUMG00000137568 +51389 RWDD1 HGNC:HGNC:20993|Ensembl:ENSG00000111832|Vega:OTTHUMG00000015441 +51390 AIG1 MIM:608514|HGNC:HGNC:21607|Ensembl:ENSG00000146416|Vega:OTTHUMG00000015721 +51393 TRPV2 MIM:606676|HGNC:HGNC:18082|Ensembl:ENSG00000187688|Vega:OTTHUMG00000058989 +51397 COMMD10 MIM:616704|HGNC:HGNC:30201|Ensembl:ENSG00000145781|Vega:OTTHUMG00000162922 +51398 WDR83OS HGNC:HGNC:30203|Ensembl:ENSG00000105583|Vega:OTTHUMG00000182617 +51399 TRAPPC4 MIM:610971|HGNC:HGNC:19943|Ensembl:ENSG00000196655|Vega:OTTHUMG00000166351 +51400 PPME1 MIM:611117|HGNC:HGNC:30178|Ensembl:ENSG00000214517|Vega:OTTHUMG00000168115 +51406 NOL7 MIM:611533|HGNC:HGNC:21040|Ensembl:ENSG00000225921|Vega:OTTHUMG00000014277 +51409 HEMK1 HGNC:HGNC:24923|Ensembl:ENSG00000114735|Vega:OTTHUMG00000156849 +51411 BIN2 MIM:605936|HGNC:HGNC:1053|Ensembl:ENSG00000110934|Vega:OTTHUMG00000185197 +51412 ACTL6B MIM:612458|HGNC:HGNC:160|Ensembl:ENSG00000077080|Vega:OTTHUMG00000159661 +51421 AMOTL2 MIM:614658|HGNC:HGNC:17812|Ensembl:ENSG00000114019|Vega:OTTHUMG00000159777 +51422 PRKAG2 MIM:602743|HGNC:HGNC:9386|Ensembl:ENSG00000106617|Vega:OTTHUMG00000157324 +51426 POLK MIM:605650|HGNC:HGNC:9183|Ensembl:ENSG00000122008|Vega:OTTHUMG00000102107 +51427 ZNF107 MIM:603989|HGNC:HGNC:12887|Ensembl:ENSG00000196247|Vega:OTTHUMG00000129433 +51428 DDX41 MIM:608170|HGNC:HGNC:18674|Ensembl:ENSG00000183258|Vega:OTTHUMG00000130858 +51429 SNX9 MIM:605952|HGNC:HGNC:14973|Ensembl:ENSG00000130340|Vega:OTTHUMG00000015903 +51430 SUCO HGNC:HGNC:1240|Ensembl:ENSG00000094975|Vega:OTTHUMG00000034839 +51433 ANAPC5 MIM:606948|HGNC:HGNC:15713|Ensembl:ENSG00000089053|Vega:OTTHUMG00000169157 +51434 ANAPC7 MIM:606949|HGNC:HGNC:17380|Ensembl:ENSG00000196510|Vega:OTTHUMG00000157009 +51435 SCARA3 MIM:602728|HGNC:HGNC:19000|Ensembl:ENSG00000168077|Vega:OTTHUMG00000163898 +51438 MAGEC2 MIM:300468|HGNC:HGNC:13574|Ensembl:ENSG00000046774|Vega:OTTHUMG00000022574 +51439 FAM8A1 HGNC:HGNC:16372|Ensembl:ENSG00000137414|Vega:OTTHUMG00000014309 +51440 HPCAL4 HGNC:HGNC:18212|Ensembl:ENSG00000116983|Vega:OTTHUMG00000009246 +51441 YTHDF2 MIM:610640|HGNC:HGNC:31675|Ensembl:ENSG00000198492|Vega:OTTHUMG00000003648 +51442 VGLL1 MIM:300583|HGNC:HGNC:20985|Ensembl:ENSG00000102243|Vega:OTTHUMG00000022509 +51444 RNF138 MIM:616319|HGNC:HGNC:17765|Ensembl:ENSG00000134758|Vega:OTTHUMG00000132265 +51447 IP6K2 MIM:606992|HGNC:HGNC:17313|Ensembl:ENSG00000068745|Vega:OTTHUMG00000133543 +51449 PCYOX1 MIM:610995|HGNC:HGNC:20588|Ensembl:ENSG00000116005|Vega:OTTHUMG00000129671 +51450 PRRX2 MIM:604675|HGNC:HGNC:21338|Ensembl:ENSG00000167157|Vega:OTTHUMG00000020790 +51451 LCMT1 MIM:610286|HGNC:HGNC:17557|Ensembl:ENSG00000205629|Vega:OTTHUMG00000177182 +51454 GULP1 MIM:608165|HGNC:HGNC:18649|Ensembl:ENSG00000144366|Vega:OTTHUMG00000132647 +51455 REV1 MIM:606134|HGNC:HGNC:14060|Ensembl:ENSG00000135945|Vega:OTTHUMG00000130636 +51458 RHCG MIM:605381|HGNC:HGNC:18140|Ensembl:ENSG00000140519|Vega:OTTHUMG00000149647 +51460 SFMBT1 MIM:607319|HGNC:HGNC:20255|Ensembl:ENSG00000163935|Vega:OTTHUMG00000159052 +51463 GPR89B MIM:612806|HGNC:HGNC:13840|Ensembl:ENSG00000188092|Vega:OTTHUMG00000013452 +51465 UBE2J1 MIM:616175|HGNC:HGNC:17598|Ensembl:ENSG00000198833|Vega:OTTHUMG00000016337 +51466 EVL MIM:616912|HGNC:HGNC:20234|Ensembl:ENSG00000196405|Vega:OTTHUMG00000171530 +51471 NAT8B MIM:608190|HGNC:HGNC:30235|Ensembl:ENSG00000204872|Vega:OTTHUMG00000152811 +51473 DCDC2 MIM:605755|HGNC:HGNC:18141|Ensembl:ENSG00000146038|Vega:OTTHUMG00000016275 +51474 LIMA1 MIM:608364|HGNC:HGNC:24636|Ensembl:ENSG00000050405|Vega:OTTHUMG00000169852 +51475 CABP2 MIM:607314|HGNC:HGNC:1385|Ensembl:ENSG00000167791|Vega:OTTHUMG00000168014 +51477 ISYNA1 MIM:611670|HGNC:HGNC:29821|Ensembl:ENSG00000105655|Vega:OTTHUMG00000179027 +51478 HSD17B7 MIM:606756|HGNC:HGNC:5215|Ensembl:ENSG00000132196|Vega:OTTHUMG00000034420 +51479 ANKFY1 MIM:607927|HGNC:HGNC:20763|Ensembl:ENSG00000185722|Vega:OTTHUMG00000177727 +51480 VCX2 MIM:300532|HGNC:HGNC:18158|Ensembl:ENSG00000177504|Vega:OTTHUMG00000021105 +51481 VCX3A MIM:300533|HGNC:HGNC:18159|Ensembl:ENSG00000169059|Vega:OTTHUMG00000021097 +51490 SPOUT1 HGNC:HGNC:26933|Ensembl:ENSG00000198917|Vega:OTTHUMG00000020762 +51491 NOP16 MIM:612861|HGNC:HGNC:26934|Ensembl:ENSG00000048162|Vega:OTTHUMG00000163186 +51493 RTCB MIM:613901|HGNC:HGNC:26935|Ensembl:ENSG00000100220|Vega:OTTHUMG00000030300 +51495 HACD3 MIM:615940|HGNC:HGNC:24175|Ensembl:ENSG00000074696|Vega:OTTHUMG00000172658 +51496 CTDSPL2 HGNC:HGNC:26936|Ensembl:ENSG00000137770|Vega:OTTHUMG00000131159 +51497 NELFCD MIM:605297|HGNC:HGNC:15934|Ensembl:ENSG00000101158|Vega:OTTHUMG00000032861 +51499 TRIAP1 MIM:614943|HGNC:HGNC:26937|Ensembl:ENSG00000170855|Vega:OTTHUMG00000047787 +51501 HIKESHI MIM:614908|HGNC:HGNC:26938|Ensembl:ENSG00000149196|Vega:OTTHUMG00000167212 +51503 CWC15 HGNC:HGNC:26939|Ensembl:ENSG00000150316|Vega:OTTHUMG00000181616 +51504 TRMT112 HGNC:HGNC:26940|Ensembl:ENSG00000173113|Vega:OTTHUMG00000167848 +51506 UFC1 MIM:610554|HGNC:HGNC:26941|Ensembl:ENSG00000143222|Vega:OTTHUMG00000033155 +51507 RTFDC1 HGNC:HGNC:15890|Ensembl:ENSG00000022277|Vega:OTTHUMG00000032801 +51510 CHMP5 MIM:610900|HGNC:HGNC:26942|Ensembl:ENSG00000086065|Vega:OTTHUMG00000019765 +51512 GTSE1 MIM:607477|HGNC:HGNC:13698|Ensembl:ENSG00000075218|Vega:OTTHUMG00000150486 +51513 ETV7 MIM:605255|HGNC:HGNC:18160|Ensembl:ENSG00000010030|Vega:OTTHUMG00000014594 +51514 DTL MIM:610617|HGNC:HGNC:30288|Ensembl:ENSG00000143476|Vega:OTTHUMG00000037133 +51517 NCKIPSD MIM:606671|HGNC:HGNC:15486|Ensembl:ENSG00000213672|Vega:OTTHUMG00000133542 +51520 LARS MIM:151350|HGNC:HGNC:6512|Ensembl:ENSG00000133706|Vega:OTTHUMG00000163429 +51522 TMEM14C MIM:615318|HGNC:HGNC:20952|Ensembl:ENSG00000111843|Vega:OTTHUMG00000014242 +51523 CXXC5 MIM:612752|HGNC:HGNC:26943|Ensembl:ENSG00000171604|Vega:OTTHUMG00000163331 +51524 TMEM138 MIM:614459|HGNC:HGNC:26944|Ensembl:ENSG00000149483|Vega:OTTHUMG00000168145 +51526 OSER1 HGNC:HGNC:16105|Ensembl:ENSG00000132823|Vega:OTTHUMG00000032518 +51527 GSKIP MIM:616605|HGNC:HGNC:20343|Ensembl:ENSG00000100744|Vega:OTTHUMG00000171420 +51528 JKAMP MIM:611176|HGNC:HGNC:20184|Ensembl:ENSG00000050130|Vega:OTTHUMG00000171054 +51529 ANAPC11 MIM:614534|HGNC:HGNC:14452|Ensembl:ENSG00000141552|Vega:OTTHUMG00000177982 +51530 ZC3HC1 HGNC:HGNC:29913|Ensembl:ENSG00000091732|Vega:OTTHUMG00000157648 +51531 TRMO HGNC:HGNC:30967|Ensembl:ENSG00000136932|Vega:OTTHUMG00000021007 +51533 PHF7 HGNC:HGNC:18458|Ensembl:ENSG00000010318|Vega:OTTHUMG00000158495 +51534 VTA1 MIM:610902|HGNC:HGNC:20954|Ensembl:ENSG00000009844|Vega:OTTHUMG00000015707 +51535 PPHLN1 MIM:608150|HGNC:HGNC:19369|Ensembl:ENSG00000134283|Vega:OTTHUMG00000169440 +51537 MTFP1 MIM:610235|HGNC:HGNC:26945|Ensembl:ENSG00000242114|Vega:OTTHUMG00000151057 +51538 ZCCHC17 HGNC:HGNC:30246|Ensembl:ENSG00000121766|Vega:OTTHUMG00000003791 +51540 SCLY MIM:611056|HGNC:HGNC:18161|Ensembl:ENSG00000132330|Vega:OTTHUMG00000133336 +51542 VPS54 MIM:614633|HGNC:HGNC:18652|Ensembl:ENSG00000143952|Vega:OTTHUMG00000152627 +51545 ZNF581 HGNC:HGNC:25017|Ensembl:ENSG00000171425|Vega:OTTHUMG00000180869 +51547 SIRT7 MIM:606212|HGNC:HGNC:14935|Ensembl:ENSG00000187531|Vega:OTTHUMG00000177957 +51548 SIRT6 MIM:606211|HGNC:HGNC:14934|Ensembl:ENSG00000077463|Vega:OTTHUMG00000181847 +51550 CINP MIM:613362|HGNC:HGNC:23789|Ensembl:ENSG00000100865|Vega:OTTHUMG00000171775 +51552 RAB14 MIM:612673|HGNC:HGNC:16524|Ensembl:ENSG00000119396|Vega:OTTHUMG00000020582 +51554 ACKR4 MIM:606065|HGNC:HGNC:1611|Ensembl:ENSG00000129048|Vega:OTTHUMG00000159768 +51555 PEX5L MIM:611058|HGNC:HGNC:30024|Ensembl:ENSG00000114757|Vega:OTTHUMG00000157363 +51557 LGSN MIM:611470|HGNC:HGNC:21016|Ensembl:ENSG00000146166|Vega:OTTHUMG00000014946 +51559 NT5DC3 MIM:611076|HGNC:HGNC:30826|Ensembl:ENSG00000111696|Vega:OTTHUMG00000157017 +51560 RAB6B MIM:615852|HGNC:HGNC:14902|Ensembl:ENSG00000154917|Vega:OTTHUMG00000159749 +51561 IL23A MIM:605580|HGNC:HGNC:15488|Ensembl:ENSG00000110944|Vega:OTTHUMG00000187402 +51562 MBIP MIM:609431|HGNC:HGNC:20427|Ensembl:ENSG00000151332|Vega:OTTHUMG00000140222 +51564 HDAC7 MIM:606542|HGNC:HGNC:14067|Ensembl:ENSG00000061273|Vega:OTTHUMG00000152968 +51566 ARMCX3 MIM:300364|HGNC:HGNC:24065|Ensembl:ENSG00000102401|Vega:OTTHUMG00000022035 +51567 TDP2 MIM:605764|HGNC:HGNC:17768|Ensembl:ENSG00000111802|Vega:OTTHUMG00000014360 +51569 UFM1 MIM:610553|HGNC:HGNC:20597|Ensembl:ENSG00000120686|Vega:OTTHUMG00000017409 +51571 FAM49B HGNC:HGNC:25216|Ensembl:ENSG00000153310|Vega:OTTHUMG00000164805 +51573 GDE1 MIM:605943|HGNC:HGNC:29644|Ensembl:ENSG00000006007|Vega:OTTHUMG00000131454 +51574 LARP7 MIM:612026|HGNC:HGNC:24912|Ensembl:ENSG00000174720|Vega:OTTHUMG00000132909 +51575 ESF1 HGNC:HGNC:15898|Ensembl:ENSG00000089048|Vega:OTTHUMG00000031906 +51581 ERVH-6 HGNC:HGNC:39058 +51582 AZIN1 MIM:607909|HGNC:HGNC:16432|Ensembl:ENSG00000155096|Vega:OTTHUMG00000164766 +51585 PCF11 MIM:608876|HGNC:HGNC:30097|Ensembl:ENSG00000165494|Vega:OTTHUMG00000167031 +51586 MED15 MIM:607372|HGNC:HGNC:14248|Ensembl:ENSG00000099917|Vega:OTTHUMG00000150810 +51588 PIAS4 MIM:605989|HGNC:HGNC:17002|Ensembl:ENSG00000105229|Vega:OTTHUMG00000181759 +51592 TRIM33 MIM:605769|HGNC:HGNC:16290|Ensembl:ENSG00000197323|Vega:OTTHUMG00000011891 +51593 SRRT MIM:614469|HGNC:HGNC:24101|Ensembl:ENSG00000087087|Vega:OTTHUMG00000157031 +51594 NBAS MIM:608025|HGNC:HGNC:15625|Ensembl:ENSG00000151779|Vega:OTTHUMG00000121153 +51596 CUTA MIM:616953|HGNC:HGNC:21101|Ensembl:ENSG00000112514|Vega:OTTHUMG00000031254 +51599 LSR MIM:616582|HGNC:HGNC:29572|Ensembl:ENSG00000105699|Vega:OTTHUMG00000183142 +51601 LIPT1 MIM:610284|HGNC:HGNC:29569|Ensembl:ENSG00000144182|Vega:OTTHUMG00000130640 +51602 NOP58 MIM:616742|HGNC:HGNC:29926|Ensembl:ENSG00000055044|Vega:OTTHUMG00000132840 +51603 METTL13 HGNC:HGNC:24248|Ensembl:ENSG00000010165|Vega:OTTHUMG00000034912 +51604 PIGT MIM:610272|HGNC:HGNC:14938|Ensembl:ENSG00000124155|Vega:OTTHUMG00000032574 +51605 TRMT6 HGNC:HGNC:20900|Ensembl:ENSG00000089195|Vega:OTTHUMG00000031816 +51606 ATP6V1H MIM:608861|HGNC:HGNC:18303|Ensembl:ENSG00000047249|Vega:OTTHUMG00000164231 +51608 GET4 MIM:612056|HGNC:HGNC:21690|Ensembl:ENSG00000239857|Vega:OTTHUMG00000112459 +51611 DPH5 MIM:611075|HGNC:HGNC:24270|Ensembl:ENSG00000117543|Vega:OTTHUMG00000010829 +51614 ERGIC3 MIM:616971|HGNC:HGNC:15927|Ensembl:ENSG00000125991|Vega:OTTHUMG00000032346 +51616 TAF9B MIM:300754|HGNC:HGNC:17306|Ensembl:ENSG00000187325|Vega:OTTHUMG00000021887 +51617 NSG2 MIM:616752|HGNC:HGNC:24955|Ensembl:ENSG00000170091|Vega:OTTHUMG00000130543 +51619 UBE2D4 HGNC:HGNC:21647|Ensembl:ENSG00000078967|Vega:OTTHUMG00000128971 +51621 KLF13 MIM:605328|HGNC:HGNC:13672|Ensembl:ENSG00000169926|Vega:OTTHUMG00000172224 +51622 CCZ1 HGNC:HGNC:21691|Ensembl:ENSG00000122674|Vega:OTTHUMG00000155502 +51626 DYNC2LI1 MIM:617083|HGNC:HGNC:24595|Ensembl:ENSG00000138036|Vega:OTTHUMG00000128656 +51629 SLC25A39 MIM:610820|HGNC:HGNC:24279|Ensembl:ENSG00000013306|Vega:OTTHUMG00000132628 +51631 LUC7L2 MIM:613056|HGNC:HGNC:21608|Ensembl:ENSG00000146963|Vega:OTTHUMG00000185163 +51633 OTUD6B MIM:612021|HGNC:HGNC:24281|Ensembl:ENSG00000155100|Vega:OTTHUMG00000150758 +51634 RBMX2 HGNC:HGNC:24282|Ensembl:ENSG00000134597|Vega:OTTHUMG00000022395 +51635 DHRS7 MIM:612833|HGNC:HGNC:21524|Ensembl:ENSG00000100612|Vega:OTTHUMG00000140331 +51637 C14orf166 MIM:610858|HGNC:HGNC:23169|Ensembl:ENSG00000087302|Vega:OTTHUMG00000152332 +51639 SF3B6 MIM:607835|HGNC:HGNC:30096|Ensembl:ENSG00000115128|Vega:OTTHUMG00000125499 +51642 MRPL48 MIM:611853|HGNC:HGNC:16653|Ensembl:ENSG00000175581|Vega:OTTHUMG00000168048 +51643 TMBIM4 MIM:616874|HGNC:HGNC:24257|Ensembl:ENSG00000155957|Ensembl:ENSG00000228144|Vega:OTTHUMG00000168972|Vega:OTTHUMG00000168973 +51645 PPIL1 MIM:601301|HGNC:HGNC:9260|Ensembl:ENSG00000137168|Vega:OTTHUMG00000014612 +51646 YPEL5 MIM:609726|HGNC:HGNC:18329|Ensembl:ENSG00000119801|Vega:OTTHUMG00000097839 +51647 FAM96B MIM:614778|HGNC:HGNC:24261|Ensembl:ENSG00000166595|Vega:OTTHUMG00000175408 +51649 MRPS23 MIM:611985|HGNC:HGNC:14509|Ensembl:ENSG00000181610|Vega:OTTHUMG00000178774 +51650 MRPS33 MIM:611993|HGNC:HGNC:16634|Ensembl:ENSG00000090263|Vega:OTTHUMG00000157456 +51651 PTRH2 MIM:608625|HGNC:HGNC:24265|Ensembl:ENSG00000141378|Vega:OTTHUMG00000154532 +51652 CHMP3 MIM:610052|HGNC:HGNC:29865|Ensembl:ENSG00000115561|Vega:OTTHUMG00000153189 +51654 CDK5RAP1 MIM:608200|HGNC:HGNC:15880|Ensembl:ENSG00000101391|Vega:OTTHUMG00000032256 +51655 RASD1 MIM:605550|HGNC:HGNC:15828|Ensembl:ENSG00000108551|Vega:OTTHUMG00000059292 +51657 STYXL1 MIM:616695|HGNC:HGNC:18165|Ensembl:ENSG00000127952|Vega:OTTHUMG00000130459 +51659 GINS2 MIM:610609|HGNC:HGNC:24575|Ensembl:ENSG00000131153|Vega:OTTHUMG00000137646 +51660 MPC1 MIM:614738|HGNC:HGNC:21606|Ensembl:ENSG00000060762|Vega:OTTHUMG00000015999 +51661 FKBP7 MIM:607062|HGNC:HGNC:3723|Ensembl:ENSG00000079150|Vega:OTTHUMG00000132577 +51663 ZFR MIM:615635|HGNC:HGNC:17277|Ensembl:ENSG00000056097|Vega:OTTHUMG00000161979 +51665 ASB1 MIM:605758|HGNC:HGNC:16011|Ensembl:ENSG00000065802|Vega:OTTHUMG00000152866 +51666 ASB4 MIM:605761|HGNC:HGNC:16009|Ensembl:ENSG00000005981|Vega:OTTHUMG00000153960 +51667 NUB1 MIM:607981|HGNC:HGNC:17623|Ensembl:ENSG00000013374|Vega:OTTHUMG00000157365 +51668 HSPB11 HGNC:HGNC:25019|Ensembl:ENSG00000081870|Vega:OTTHUMG00000008408 +51669 SARAF MIM:614768|HGNC:HGNC:28789|Ensembl:ENSG00000133872|Vega:OTTHUMG00000133397 +51673 TPPP3 MIM:616957|HGNC:HGNC:24162|Ensembl:ENSG00000159713|Vega:OTTHUMG00000137516 +51676 ASB2 MIM:605759|HGNC:HGNC:16012|Ensembl:ENSG00000100628|Vega:OTTHUMG00000171298 +51678 MPP6 MIM:606959|HGNC:HGNC:18167|Ensembl:ENSG00000105926|Vega:OTTHUMG00000023507 +51684 SUFU MIM:607035|HGNC:HGNC:16466|Ensembl:ENSG00000107882|Vega:OTTHUMG00000018966 +51686 OAZ3 MIM:605138|HGNC:HGNC:8097|Ensembl:ENSG00000143450|Vega:OTTHUMG00000013061 +51690 LSM7 MIM:607287|HGNC:HGNC:20470|Ensembl:ENSG00000130332|Vega:OTTHUMG00000180441 +51691 LSM8 MIM:607288|HGNC:HGNC:20471|Ensembl:ENSG00000128534|Vega:OTTHUMG00000156956 +51692 CPSF3 MIM:606029|HGNC:HGNC:2326|Ensembl:ENSG00000119203|Vega:OTTHUMG00000090415 +51693 TRAPPC2L MIM:610970|HGNC:HGNC:30887|Ensembl:ENSG00000167515|Vega:OTTHUMG00000137861 +51696 HECA MIM:607977|HGNC:HGNC:21041|Ensembl:ENSG00000112406|Vega:OTTHUMG00000015686 +51699 VPS29 MIM:606932|HGNC:HGNC:14340|Ensembl:ENSG00000111237|Vega:OTTHUMG00000169527 +51700 CYB5R2 MIM:608342|HGNC:HGNC:24376|Ensembl:ENSG00000166394|Vega:OTTHUMG00000165665 +51701 NLK MIM:609476|HGNC:HGNC:29858|Ensembl:ENSG00000087095|Vega:OTTHUMG00000132451 +51702 PADI3 MIM:606755|HGNC:HGNC:18337|Ensembl:ENSG00000142619|Vega:OTTHUMG00000002373 +51703 ACSL5 MIM:605677|HGNC:HGNC:16526|Ensembl:ENSG00000197142|Vega:OTTHUMG00000019060 +51704 GPRC5B MIM:605948|HGNC:HGNC:13308|Ensembl:ENSG00000167191|Vega:OTTHUMG00000131460 +51705 EMCN MIM:608350|HGNC:HGNC:16041|Ensembl:ENSG00000164035|Vega:OTTHUMG00000131051 +51706 CYB5R1 MIM:608341|HGNC:HGNC:13397|Ensembl:ENSG00000159348|Vega:OTTHUMG00000041387 +51710 ZNF44 MIM:194542|HGNC:HGNC:13110|Ensembl:ENSG00000197857|Vega:OTTHUMG00000156424 +51714 SELENOT MIM:607912|HGNC:HGNC:18136|Ensembl:ENSG00000198843|Vega:OTTHUMG00000159825 +51715 RAB23 MIM:606144|HGNC:HGNC:14263|Ensembl:ENSG00000112210|Vega:OTTHUMG00000014918 +51716 CES1P1 HGNC:HGNC:18546|Ensembl:ENSG00000228695 +51719 CAB39 MIM:612174|HGNC:HGNC:20292|Ensembl:ENSG00000135932|Vega:OTTHUMG00000133220 +51720 UIMC1 MIM:609433|HGNC:HGNC:30298|Ensembl:ENSG00000087206|Vega:OTTHUMG00000130852 +51725 FBXO40 MIM:609107|HGNC:HGNC:29816|Ensembl:ENSG00000163833|Vega:OTTHUMG00000159410 +51726 DNAJB11 MIM:611341|HGNC:HGNC:14889|Ensembl:ENSG00000090520|Vega:OTTHUMG00000156614 +51727 CMPK1 MIM:191710|HGNC:HGNC:18170|Ensembl:ENSG00000162368|Vega:OTTHUMG00000007849 +51728 POLR3K MIM:606007|HGNC:HGNC:14121|Ensembl:ENSG00000161980|Vega:OTTHUMG00000060722 +51729 WBP11 HGNC:HGNC:16461|Ensembl:ENSG00000084463|Vega:OTTHUMG00000168737 +51733 UPB1 MIM:606673|HGNC:HGNC:16297|Ensembl:ENSG00000100024|Vega:OTTHUMG00000150749 +51734 MSRB1 MIM:606216|HGNC:HGNC:14133|Ensembl:ENSG00000198736|Vega:OTTHUMG00000129143 +51735 RAPGEF6 MIM:610499|HGNC:HGNC:20655|Ensembl:ENSG00000158987|Ensembl:ENSG00000273217|Vega:OTTHUMG00000162683|Vega:OTTHUMG00000162686 +51738 GHRL MIM:605353|HGNC:HGNC:18129|Ensembl:ENSG00000157017|Vega:OTTHUMG00000155360 +51741 WWOX MIM:605131|HGNC:HGNC:12799|Ensembl:ENSG00000186153|Vega:OTTHUMG00000176851 +51742 ARID4B MIM:609696|HGNC:HGNC:15550|Ensembl:ENSG00000054267|Vega:OTTHUMG00000039621 +51744 CD244 MIM:605554|HGNC:HGNC:18171|Ensembl:ENSG00000122223|Vega:OTTHUMG00000028606 +51747 LUC7L3 MIM:609434|HGNC:HGNC:24309|Ensembl:ENSG00000108848|Vega:OTTHUMG00000162257 +51750 RTEL1 MIM:608833|HGNC:HGNC:15888|Ensembl:ENSG00000026036|Ensembl:ENSG00000258366|Vega:OTTHUMG00000032992|Vega:OTTHUMG00000170363 +51751 HIGD1B HGNC:HGNC:24318|Ensembl:ENSG00000131097|Vega:OTTHUMG00000179864 +51752 ERAP1 MIM:606832|HGNC:HGNC:18173|Ensembl:ENSG00000164307|Vega:OTTHUMG00000128721 +51754 TMEM8B MIM:616888|HGNC:HGNC:21427|Ensembl:ENSG00000137103|Vega:OTTHUMG00000019885 +51755 CDK12 MIM:615514|HGNC:HGNC:24224|Ensembl:ENSG00000167258|Vega:OTTHUMG00000133214 +51759 C9orf78 HGNC:HGNC:24932|Ensembl:ENSG00000136819|Vega:OTTHUMG00000020796 +51760 SYT17 HGNC:HGNC:24119|Ensembl:ENSG00000103528|Vega:OTTHUMG00000131461 +51761 ATP8A2 MIM:605870|HGNC:HGNC:13533|Ensembl:ENSG00000132932|Vega:OTTHUMG00000016611 +51762 RAB8B MIM:613532|HGNC:HGNC:30273|Ensembl:ENSG00000166128|Vega:OTTHUMG00000132862 +51763 INPP5K MIM:607875|HGNC:HGNC:33882|Ensembl:ENSG00000132376|Vega:OTTHUMG00000150648 +51764 GNG13 MIM:607298|HGNC:HGNC:14131|Ensembl:ENSG00000127588|Vega:OTTHUMG00000047839 +51765 STK26 MIM:300547|HGNC:HGNC:18174|Ensembl:ENSG00000134602|Vega:OTTHUMG00000022420 +51768 TM7SF3 MIM:605181|HGNC:HGNC:23049|Ensembl:ENSG00000064115|Vega:OTTHUMG00000169243 +51773 RSF1 MIM:608522|HGNC:HGNC:18118|Ensembl:ENSG00000048649|Vega:OTTHUMG00000150433 +51776 MAP3K20 MIM:609479|HGNC:HGNC:17797|Ensembl:ENSG00000091436|Vega:OTTHUMG00000132297 +51778 MYOZ2 MIM:605602|HGNC:HGNC:1330|Ensembl:ENSG00000172399|Vega:OTTHUMG00000132968 +51780 KDM3B MIM:609373|HGNC:HGNC:1337|Ensembl:ENSG00000120733|Vega:OTTHUMG00000163469 +51802 ASIC5 MIM:616693|HGNC:HGNC:17537|Ensembl:ENSG00000256394|Vega:OTTHUMG00000161941 +51804 SIX4 MIM:606342|HGNC:HGNC:10890|Ensembl:ENSG00000100625|Vega:OTTHUMG00000028996 +51805 COQ3 MIM:605196|HGNC:HGNC:18175|Ensembl:ENSG00000132423|Vega:OTTHUMG00000015264 +51806 CALML5 MIM:605183|HGNC:HGNC:18180|Ensembl:ENSG00000178372|Vega:OTTHUMG00000017598 +51807 TUBA8 MIM:605742|HGNC:HGNC:12410|Ensembl:ENSG00000183785|Vega:OTTHUMG00000150097 +51808 PHAX MIM:604924|HGNC:HGNC:10241|Ensembl:ENSG00000164902|Vega:OTTHUMG00000163273 +51809 GALNT7 MIM:605005|HGNC:HGNC:4129|Ensembl:ENSG00000109586|Vega:OTTHUMG00000160817 +51816 ADA2 MIM:607575|HGNC:HGNC:1839|Ensembl:ENSG00000093072|Vega:OTTHUMG00000030726 +53335 BCL11A MIM:606557|HGNC:HGNC:13221|Ensembl:ENSG00000119866|Vega:OTTHUMG00000129420 +53336 CPXCR1 HGNC:HGNC:2332|Ensembl:ENSG00000147183|Vega:OTTHUMG00000021950 +53338 CAPZA1P HGNC:HGNC:1489 +53339 BTBD1 MIM:608530|HGNC:HGNC:1120|Ensembl:ENSG00000064726|Vega:OTTHUMG00000147364 +53340 SPA17 MIM:608621|HGNC:HGNC:11210|Ensembl:ENSG00000064199|Vega:OTTHUMG00000165927 +53341 MHAC MIM:605013|HGNC:HGNC:7065 +53342 IL17D MIM:607587|HGNC:HGNC:5984|Ensembl:ENSG00000172458|Vega:OTTHUMG00000016521 +53343 NUDT9 MIM:606022|HGNC:HGNC:8056|Ensembl:ENSG00000170502|Vega:OTTHUMG00000130591 +53344 CHIC1 MIM:300922|HGNC:HGNC:1934|Ensembl:ENSG00000204116|Vega:OTTHUMG00000021835 +53345 TM6SF2 MIM:606563|HGNC:HGNC:11861|Ensembl:ENSG00000213996|Vega:OTTHUMG00000182222 +53346 TM6SF1 MIM:606562|HGNC:HGNC:11860|Ensembl:ENSG00000136404|Vega:OTTHUMG00000147365 +53347 UBASH3A MIM:605736|HGNC:HGNC:12462|Ensembl:ENSG00000160185|Vega:OTTHUMG00000086805 +53349 ZFYVE1 MIM:605471|HGNC:HGNC:13180|Ensembl:ENSG00000165861|Vega:OTTHUMG00000171365 +53353 LRP1B MIM:608766|HGNC:HGNC:6693|Ensembl:ENSG00000168702|Vega:OTTHUMG00000131799 +53354 PANK1 MIM:606160|HGNC:HGNC:8598|Ensembl:ENSG00000152782|Vega:OTTHUMG00000018718 +53358 SHC3 MIM:605263|HGNC:HGNC:18181|Ensembl:ENSG00000148082|Vega:OTTHUMG00000020179 +53366 SM2 MIM:604201 +53368 MDC1B MIM:604801 +53369 HDL3 MIM:604802 +53371 NUP54 MIM:607607|HGNC:HGNC:17359|Ensembl:ENSG00000138750|Vega:OTTHUMG00000130098 +53373 TPCN1 MIM:609666|HGNC:HGNC:18182|Ensembl:ENSG00000186815|Vega:OTTHUMG00000169625 +53383 CCDC90AP1 HGNC:HGNC:1217 +53400 SMG6-IT1 HGNC:HGNC:1220 +53405 CLIC5 MIM:607293|HGNC:HGNC:13517|Ensembl:ENSG00000112782|Vega:OTTHUMG00000014775 +53407 STX18 MIM:606046|HGNC:HGNC:15942|Ensembl:ENSG00000168818|Vega:OTTHUMG00000090331 +53409 ATP5LP3 HGNC:HGNC:13216 +53410 ATP5LP2 HGNC:HGNC:13215 +53411 ATP5LP1 HGNC:HGNC:13214 +53615 MBD3 MIM:603573|HGNC:HGNC:6918|Ensembl:ENSG00000071655|Vega:OTTHUMG00000180081 +53616 ADAM22 MIM:603709|HGNC:HGNC:201|Ensembl:ENSG00000008277|Vega:OTTHUMG00000137417 +53630 BCO1 MIM:605748|HGNC:HGNC:13815|Ensembl:ENSG00000135697|Vega:OTTHUMG00000137630 +53632 PRKAG3 MIM:604976|HGNC:HGNC:9387|Ensembl:ENSG00000115592|Vega:OTTHUMG00000133078 +53635 PTOV1 MIM:610195|HGNC:HGNC:9632|Ensembl:ENSG00000104960|Vega:OTTHUMG00000183162 +53637 S1PR5 MIM:605146|HGNC:HGNC:14299|Ensembl:ENSG00000180739|Vega:OTTHUMG00000180581 +53820 RIPPLY3 MIM:609892|HGNC:HGNC:3047|Ensembl:ENSG00000183145|Vega:OTTHUMG00000086639 +53822 FXYD7 MIM:606684|HGNC:HGNC:4034|Ensembl:ENSG00000221946|Vega:OTTHUMG00000182348 +53826 FXYD6 MIM:606683|HGNC:HGNC:4030|Ensembl:ENSG00000137726|Vega:OTTHUMG00000166991 +53827 FXYD5 MIM:606669|HGNC:HGNC:4029|Ensembl:ENSG00000089327|Vega:OTTHUMG00000048092 +53828 FXYD4 MIM:616926|HGNC:HGNC:4028|Ensembl:ENSG00000150201|Vega:OTTHUMG00000018027 +53829 P2RY13 MIM:606380|HGNC:HGNC:4537|Ensembl:ENSG00000181631|Vega:OTTHUMG00000155745 +53831 GPR84 MIM:606383|HGNC:HGNC:4535|Ensembl:ENSG00000139572|Vega:OTTHUMG00000169839 +53832 IL20RA MIM:605620|HGNC:HGNC:6003|Ensembl:ENSG00000016402|Vega:OTTHUMG00000015654 +53833 IL20RB MIM:605621|HGNC:HGNC:6004|Ensembl:ENSG00000174564|Vega:OTTHUMG00000159779 +53834 FGFRL1 MIM:605830|HGNC:HGNC:3693|Ensembl:ENSG00000127418|Vega:OTTHUMG00000118998 +53836 GPR87 MIM:606379|HGNC:HGNC:4538|Ensembl:ENSG00000138271|Vega:OTTHUMG00000159858 +53838 C11orf24 MIM:610880|HGNC:HGNC:1174|Ensembl:ENSG00000171067|Vega:OTTHUMG00000167478 +53840 TRIM34 MIM:605684|HGNC:HGNC:10063|Ensembl:ENSG00000258659|Vega:OTTHUMG00000066892 +53841 CDHR5 MIM:606839|HGNC:HGNC:7521|Ensembl:ENSG00000099834|Vega:OTTHUMG00000132018 +53842 CLDN22 HGNC:HGNC:2044|Ensembl:ENSG00000177300|Vega:OTTHUMG00000160627 +53844 COPG2IT1 MIM:610581|HGNC:HGNC:2238 +53904 MYO3A MIM:606808|HGNC:HGNC:7601|Ensembl:ENSG00000095777|Vega:OTTHUMG00000017837 +53905 DUOX1 MIM:606758|HGNC:HGNC:3062|Ensembl:ENSG00000137857|Vega:OTTHUMG00000171987 +53916 RAB4B MIM:612945|HGNC:HGNC:9782|Ensembl:ENSG00000167578|Ensembl:ENSG00000171570|Vega:OTTHUMG00000182694|Vega:OTTHUMG00000182702 +53917 RAB24 MIM:612415|HGNC:HGNC:9765|Ensembl:ENSG00000169228|Vega:OTTHUMG00000130849 +53918 PELO MIM:605757|HGNC:HGNC:8829|Ensembl:ENSG00000152684|Vega:OTTHUMG00000096973 +53919 SLCO1C1 MIM:613389|HGNC:HGNC:13819|Ensembl:ENSG00000139155|Vega:OTTHUMG00000168966 +53938 PPIL3 MIM:615811|HGNC:HGNC:9262|Ensembl:ENSG00000240344|Vega:OTTHUMG00000132782 +53940 FTHL17 MIM:300308|HGNC:HGNC:3987|Ensembl:ENSG00000132446|Vega:OTTHUMG00000021332 +53942 CNTN5 MIM:607219|HGNC:HGNC:2175|Ensembl:ENSG00000149972|Vega:OTTHUMG00000167579 +53944 CSNK1G1 MIM:606274|HGNC:HGNC:2454|Ensembl:ENSG00000169118|Vega:OTTHUMG00000133019 +53947 A4GALT MIM:607922|HGNC:HGNC:18149|Ensembl:ENSG00000128274|Vega:OTTHUMG00000150744 +53981 CPSF2 MIM:606028|HGNC:HGNC:2325|Ensembl:ENSG00000165934|Vega:OTTHUMG00000171181 +54012 ZNF299P HGNC:HGNC:13088 +54014 BRWD1 HGNC:HGNC:12760|Ensembl:ENSG00000185658|Vega:OTTHUMG00000066030 +54015 VDAC2P1 HGNC:HGNC:12673 +54016 TUBAP HGNC:HGNC:12411 +54019 SLC6A6P1 HGNC:HGNC:11053 +54020 SLC37A1 MIM:608094|HGNC:HGNC:11024|Ensembl:ENSG00000160190|Vega:OTTHUMG00000086803 +54021 SRSF9P1 HGNC:HGNC:10792 +54022 RPS5P3 HGNC:HGNC:10427 +54024 RPS26P1 HGNC:HGNC:10415 +54025 RPS20P1 HGNC:HGNC:10408 +54026 RPL34P3 HGNC:HGNC:10343 +54027 RPL31P1 HGNC:HGNC:10335 +54028 RPL23P2 HGNC:HGNC:10324 +54029 RPL23AP4 HGNC:HGNC:10321 +54031 RIMKLBP1 HGNC:HGNC:34034 +54032 RBPMSLP HGNC:HGNC:9923 +54033 RBM11 HGNC:HGNC:9897|Ensembl:ENSG00000185272|Vega:OTTHUMG00000074263 +54034 RAD23BP3 HGNC:HGNC:9814 +54035 PSMD4P1 HGNC:HGNC:9562 +54036 PPP1R2P2 HGNC:HGNC:9290 +54038 POLR2CP1 HGNC:HGNC:9190 +54039 PCBP3 MIM:608502|HGNC:HGNC:8651|Ensembl:ENSG00000183570|Vega:OTTHUMG00000090399 +54041 VN1R8P HGNC:HGNC:8497 +54043 MYL6P1 HGNC:HGNC:7588 +54044 KRT18P2 HGNC:HGNC:6435 +54045 IMMTP1 HGNC:HGNC:6048 +54047 HSPD1P7 HGNC:HGNC:5268 +54048 HMGN1P2 HGNC:HGNC:4985 +54049 H2AFZP1 HGNC:HGNC:4742 +54050 GAPDHP14 HGNC:HGNC:4160 +54051 FDPSP6 HGNC:HGNC:3637 +54052 EIF4A1P1 HGNC:HGNC:3283 +54053 EIF3FP1 HGNC:HGNC:3276 +54054 EEF1A1P1 HGNC:HGNC:3191 +54055 CYP4F29P HGNC:HGNC:2647|Ensembl:ENSG00000228314 +54058 C21orf58 HGNC:HGNC:1300|Ensembl:ENSG00000160298|Vega:OTTHUMG00000090634 +54059 YBEY MIM:617461|HGNC:HGNC:1299|Ensembl:ENSG00000182362|Vega:OTTHUMG00000090632 +54064 LINC00160 HGNC:HGNC:1294|Ensembl:ENSG00000230978 +54065 SMIM11A HGNC:HGNC:1293|Ensembl:ENSG00000205670|Vega:OTTHUMG00000086193 +54067 C21orf62-AS1 HGNC:HGNC:1290 +54069 MIS18A HGNC:HGNC:1286|Ensembl:ENSG00000159055|Vega:OTTHUMG00000085308 +54072 LINC00158 HGNC:HGNC:1283|Ensembl:ENSG00000185433 +54075 CHODL-AS1 HGNC:HGNC:1279 +54082 TSPEAR-AS1 HGNC:HGNC:1271|Ensembl:ENSG00000235890 +54084 TSPEAR MIM:612920|HGNC:HGNC:1268|Ensembl:ENSG00000175894|Vega:OTTHUMG00000041215 +54088 LINC00113 HGNC:HGNC:1264|Ensembl:ENSG00000225298 +54089 LINC00112 HGNC:HGNC:1263|Ensembl:ENSG00000232401 +54090 LINC00111 HGNC:HGNC:1262 +54093 SETD4 HGNC:HGNC:1258|Ensembl:ENSG00000185917|Vega:OTTHUMG00000086483 +54097 FAM3B MIM:608617|HGNC:HGNC:1253|Ensembl:ENSG00000183844|Vega:OTTHUMG00000086752 +54098 C1QBPP1 HGNC:HGNC:1244 +54099 FBXW11P1 HGNC:HGNC:1145 +54101 RIPK4 MIM:605706|HGNC:HGNC:496|Ensembl:ENSG00000183421|Vega:OTTHUMG00000086770 +54102 CLIC6 MIM:615321|HGNC:HGNC:2065|Ensembl:ENSG00000159212|Vega:OTTHUMG00000086237 +54103 GSAP MIM:613552|HGNC:HGNC:28042|Ensembl:ENSG00000186088|Vega:OTTHUMG00000150504 +54106 TLR9 MIM:605474|HGNC:HGNC:15633|Ensembl:ENSG00000239732|Vega:OTTHUMG00000158106 +54107 POLE3 MIM:607267|HGNC:HGNC:13546|Ensembl:ENSG00000148229|Vega:OTTHUMG00000020523 +54108 CHRAC1 MIM:607268|HGNC:HGNC:13544|Ensembl:ENSG00000104472|Vega:OTTHUMG00000164207 +54109 CORD8 MIM:605549|HGNC:HGNC:2251 +54110 RP29 MIM:612165|HGNC:HGNC:10282 +54111 HNB1 HGNC:HGNC:5020 +54112 GPR88 MIM:607468|HGNC:HGNC:4539|Ensembl:ENSG00000181656|Vega:OTTHUMG00000010981 +54113 VUR MIM:193000 +54114 ODPF MIM:300244 +54115 PTOS2 MIM:300245 +54119 EIM MIM:605021 +54143 LINC00308 HGNC:HGNC:16023|Ensembl:ENSG00000184856 +54145 H2BFS HGNC:HGNC:4762 +54147 BACH1-IT3 HGNC:HGNC:16455 +54148 MRPL39 MIM:611845|HGNC:HGNC:14027|Ensembl:ENSG00000154719|Vega:OTTHUMG00000078371 +54149 C21orf91 HGNC:HGNC:16459|Ensembl:ENSG00000154642|Vega:OTTHUMG00000074509 +54165 DCUN1D1 MIM:605905|HGNC:HGNC:18184|Ensembl:ENSG00000043093|Vega:OTTHUMG00000158314 +54187 NANS MIM:605202|HGNC:HGNC:19237|Ensembl:ENSG00000095380|Vega:OTTHUMG00000020341 +54205 CYCS MIM:123970|HGNC:HGNC:19986|Ensembl:ENSG00000172115|Vega:OTTHUMG00000128495 +54206 ERRFI1 MIM:608069|HGNC:HGNC:18185|Ensembl:ENSG00000116285|Vega:OTTHUMG00000001221 +54207 KCNK10 MIM:605873|HGNC:HGNC:6273|Ensembl:ENSG00000100433|Vega:OTTHUMG00000170743 +54209 TREM2 MIM:605086|HGNC:HGNC:17761|Ensembl:ENSG00000095970|Vega:OTTHUMG00000014671 +54210 TREM1 MIM:605085|HGNC:HGNC:17760|Ensembl:ENSG00000124731|Vega:OTTHUMG00000014674 +54212 SNTG1 MIM:608714|HGNC:HGNC:13740|Ensembl:ENSG00000147481|Vega:OTTHUMG00000164257 +54221 SNTG2 MIM:608715|HGNC:HGNC:13741|Ensembl:ENSG00000172554|Vega:OTTHUMG00000151370 +54328 GPR173 MIM:300253|HGNC:HGNC:18186|Ensembl:ENSG00000184194|Vega:OTTHUMG00000021596 +54329 GPR85 MIM:605188|HGNC:HGNC:4536|Ensembl:ENSG00000164604|Vega:OTTHUMG00000156933 +54331 GNG2 MIM:606981|HGNC:HGNC:4404|Ensembl:ENSG00000186469|Vega:OTTHUMG00000171083 +54332 GDAP1 MIM:606598|HGNC:HGNC:15968|Ensembl:ENSG00000104381|Vega:OTTHUMG00000164509 +54344 DPM3 MIM:605951|HGNC:HGNC:3007|Ensembl:ENSG00000179085|Vega:OTTHUMG00000035335 +54345 SOX18 MIM:601618|HGNC:HGNC:11194|Ensembl:ENSG00000203883|Vega:OTTHUMG00000033017 +54346 UNC93A MIM:607995|HGNC:HGNC:12570|Ensembl:ENSG00000112494|Vega:OTTHUMG00000016021 +54360 CYTL1 MIM:607930|HGNC:HGNC:24435|Ensembl:ENSG00000170891|Vega:OTTHUMG00000125479 +54361 WNT4 MIM:603490|HGNC:HGNC:12783|Ensembl:ENSG00000162552|Vega:OTTHUMG00000002894 +54362 DFNM1 MIM:605429|HGNC:HGNC:2842 +54363 HAO1 MIM:605023|HGNC:HGNC:4809|Ensembl:ENSG00000101323|Vega:OTTHUMG00000031841 +54386 TERF2IP MIM:605061|HGNC:HGNC:19246|Ensembl:ENSG00000166848|Vega:OTTHUMG00000177136 +54407 SLC38A2 MIM:605180|HGNC:HGNC:13448|Ensembl:ENSG00000134294|Vega:OTTHUMG00000169471 +54413 NLGN3 MIM:300336|HGNC:HGNC:14289|Ensembl:ENSG00000196338|Vega:OTTHUMG00000021790 +54414 SIAE MIM:610079|HGNC:HGNC:18187|Ensembl:ENSG00000110013|Vega:OTTHUMG00000165926 +54429 TAS2R5 MIM:605062|HGNC:HGNC:14912|Ensembl:ENSG00000127366|Vega:OTTHUMG00000157632 +54431 DNAJC10 MIM:607987|HGNC:HGNC:24637|Ensembl:ENSG00000077232|Vega:OTTHUMG00000154209 +54432 YIPF1 MIM:617521|HGNC:HGNC:25231|Ensembl:ENSG00000058799|Vega:OTTHUMG00000008074 +54433 GAR1 MIM:606468|HGNC:HGNC:14264|Ensembl:ENSG00000109534|Vega:OTTHUMG00000161108 +54434 SSH1 MIM:606778|HGNC:HGNC:30579|Ensembl:ENSG00000084112|Vega:OTTHUMG00000169371 +54435 HCG4 HGNC:HGNC:21241 +54436 SH3TC1 HGNC:HGNC:26009|Ensembl:ENSG00000125089|Vega:OTTHUMG00000160934 +54437 SEMA5B MIM:609298|HGNC:HGNC:10737|Ensembl:ENSG00000082684|Vega:OTTHUMG00000140392 +54438 GFOD1 HGNC:HGNC:21096|Ensembl:ENSG00000145990|Vega:OTTHUMG00000014276 +54439 RBM27 HGNC:HGNC:29243|Ensembl:ENSG00000091009|Ensembl:ENSG00000275740|Vega:OTTHUMG00000163436|Vega:OTTHUMG00000188625 +54440 SASH3 MIM:300441|HGNC:HGNC:15975|Ensembl:ENSG00000122122|Vega:OTTHUMG00000022372 +54441 STAG3L1 HGNC:HGNC:33852 +54442 KCTD5 MIM:611285|HGNC:HGNC:21423|Ensembl:ENSG00000167977|Vega:OTTHUMG00000128930 +54443 ANLN MIM:616027|HGNC:HGNC:14082|Ensembl:ENSG00000011426|Vega:OTTHUMG00000023143 +54453 RIN2 MIM:610222|HGNC:HGNC:18750|Ensembl:ENSG00000132669|Vega:OTTHUMG00000031996 +54454 ATAD2B MIM:615347|HGNC:HGNC:29230|Ensembl:ENSG00000119778|Vega:OTTHUMG00000151902 +54455 FBXO42 MIM:609109|HGNC:HGNC:29249|Ensembl:ENSG00000037637|Vega:OTTHUMG00000002218 +54456 MOV10L1 MIM:605794|HGNC:HGNC:7201|Ensembl:ENSG00000073146|Vega:OTTHUMG00000044648 +54457 TAF7L MIM:300314|HGNC:HGNC:11548|Ensembl:ENSG00000102387|Vega:OTTHUMG00000022021 +54458 PRR13 MIM:610459|HGNC:HGNC:24528|Ensembl:ENSG00000205352|Vega:OTTHUMG00000170049 +54460 MRPS21 MIM:611984|HGNC:HGNC:14046|Ensembl:ENSG00000266472|Vega:OTTHUMG00000012544 +54461 FBXW5 MIM:609072|HGNC:HGNC:13613|Ensembl:ENSG00000159069|Vega:OTTHUMG00000020967 +54462 CCSER2 HGNC:HGNC:29197|Ensembl:ENSG00000107771|Vega:OTTHUMG00000018641 +54463 RETREG1 MIM:613114|HGNC:HGNC:25964|Ensembl:ENSG00000154153|Vega:OTTHUMG00000161788 +54464 XRN1 MIM:607994|HGNC:HGNC:30654|Ensembl:ENSG00000114127|Vega:OTTHUMG00000159251 +54465 ETAA1 MIM:613196|HGNC:HGNC:24648|Ensembl:ENSG00000143971|Vega:OTTHUMG00000129545 +54466 SPIN2A MIM:300621|HGNC:HGNC:20694|Ensembl:ENSG00000147059|Vega:OTTHUMG00000022705 +54467 ANKIB1 HGNC:HGNC:22215|Ensembl:ENSG00000001629|Vega:OTTHUMG00000155859 +54468 MIOS MIM:615359|HGNC:HGNC:21905|Ensembl:ENSG00000164654|Vega:OTTHUMG00000152440 +54469 ZFAND6 MIM:610183|HGNC:HGNC:30164|Ensembl:ENSG00000086666|Vega:OTTHUMG00000144169 +54470 ARMCX6 HGNC:HGNC:26094|Ensembl:ENSG00000198960|Vega:OTTHUMG00000022034 +54471 MIEF1 MIM:615497|HGNC:HGNC:25979|Ensembl:ENSG00000100335|Vega:OTTHUMG00000151105 +54472 TOLLIP MIM:606277|HGNC:HGNC:16476|Ensembl:ENSG00000078902|Vega:OTTHUMG00000133333 +54474 KRT20 MIM:608218|HGNC:HGNC:20412|Ensembl:ENSG00000171431|Vega:OTTHUMG00000133366 +54475 NLE1 HGNC:HGNC:19889|Ensembl:ENSG00000073536|Vega:OTTHUMG00000132928 +54476 RNF216 MIM:609948|HGNC:HGNC:21698|Ensembl:ENSG00000011275|Vega:OTTHUMG00000155500 +54477 PLEKHA5 MIM:607770|HGNC:HGNC:30036|Ensembl:ENSG00000052126|Vega:OTTHUMG00000167921 +54478 PIMREG HGNC:HGNC:25483|Ensembl:ENSG00000129195|Vega:OTTHUMG00000177832 +54480 CHPF2 MIM:608037|HGNC:HGNC:29270|Ensembl:ENSG00000033100|Vega:OTTHUMG00000157380 +54482 TRMT13 HGNC:HGNC:25502|Ensembl:ENSG00000122435|Vega:OTTHUMG00000010841 +54487 DGCR8 MIM:609030|HGNC:HGNC:2847|Ensembl:ENSG00000128191|Vega:OTTHUMG00000150503 +54490 UGT2B28 MIM:606497|HGNC:HGNC:13479|Ensembl:ENSG00000135226|Vega:OTTHUMG00000129401 +54491 FAM105A HGNC:HGNC:25629|Ensembl:ENSG00000145569|Vega:OTTHUMG00000131056 +54492 NEURL1B MIM:615893|HGNC:HGNC:35422|Ensembl:ENSG00000214357|Vega:OTTHUMG00000163281 +54494 C11orf71 HGNC:HGNC:25937|Ensembl:ENSG00000180425 +54495 TMX3 MIM:616102|HGNC:HGNC:24718|Ensembl:ENSG00000166479|Vega:OTTHUMG00000172713 +54496 PRMT7 MIM:610087|HGNC:HGNC:25557|Ensembl:ENSG00000132600|Vega:OTTHUMG00000137556 +54497 HEATR5B HGNC:HGNC:29273|Ensembl:ENSG00000008869|Vega:OTTHUMG00000152158 +54498 SMOX MIM:615854|HGNC:HGNC:15862|Ensembl:ENSG00000088826|Vega:OTTHUMG00000031777 +54499 TMCO1 MIM:614123|HGNC:HGNC:18188|Ensembl:ENSG00000143183|Vega:OTTHUMG00000034672 +54501 CLQTL1 MIM:604595 +54502 RBM47 HGNC:HGNC:30358|Ensembl:ENSG00000163694|Vega:OTTHUMG00000128598 +54503 ZDHHC13 MIM:612815|HGNC:HGNC:18413|Ensembl:ENSG00000177054|Vega:OTTHUMG00000166099 +54504 CPVL MIM:609780|HGNC:HGNC:14399|Ensembl:ENSG00000106066|Vega:OTTHUMG00000023669 +54505 DHX29 MIM:612720|HGNC:HGNC:15815|Ensembl:ENSG00000067248|Vega:OTTHUMG00000162313 +54507 ADAMTSL4 MIM:610113|HGNC:HGNC:19706|Ensembl:ENSG00000143382|Vega:OTTHUMG00000034863 +54508 EPB41L4A-AS2 HGNC:HGNC:25643|Ensembl:ENSG00000278921 +54509 RHOF HGNC:HGNC:15703|Ensembl:ENSG00000139725|Vega:OTTHUMG00000169077 +54510 PCDH18 MIM:608287|HGNC:HGNC:14268|Ensembl:ENSG00000189184|Vega:OTTHUMG00000161348 +54511 HMGCLL1 HGNC:HGNC:21359|Ensembl:ENSG00000146151|Vega:OTTHUMG00000014902 +54512 EXOSC4 MIM:606491|HGNC:HGNC:18189|Ensembl:ENSG00000178896|Vega:OTTHUMG00000165437 +54514 DDX4 MIM:605281|HGNC:HGNC:18700|Ensembl:ENSG00000152670|Vega:OTTHUMG00000097044 +54516 MTRF1L MIM:613542|HGNC:HGNC:21051|Ensembl:ENSG00000112031|Vega:OTTHUMG00000015857 +54517 PUS7 MIM:616261|HGNC:HGNC:26033|Ensembl:ENSG00000091127|Vega:OTTHUMG00000157399 +54518 APBB1IP MIM:609036|HGNC:HGNC:17379|Ensembl:ENSG00000077420|Vega:OTTHUMG00000017841 +54520 CCDC93 HGNC:HGNC:25611|Ensembl:ENSG00000125633|Vega:OTTHUMG00000058517 +54521 WDR44 HGNC:HGNC:30512|Ensembl:ENSG00000131725|Vega:OTTHUMG00000022254 +54522 ANKRD16 HGNC:HGNC:23471|Ensembl:ENSG00000134461|Vega:OTTHUMG00000017610 +54529 ASNSD1 HGNC:HGNC:24910|Ensembl:ENSG00000138381|Vega:OTTHUMG00000132665 +54531 MIER2 HGNC:HGNC:29210|Ensembl:ENSG00000105556|Vega:OTTHUMG00000180532 +54532 USP53 MIM:617431|HGNC:HGNC:29255|Ensembl:ENSG00000145390|Vega:OTTHUMG00000161331 +54534 MRPL50 MIM:611854|HGNC:HGNC:16654|Ensembl:ENSG00000136897|Vega:OTTHUMG00000020384 +54535 CCHCR1 MIM:605310|HGNC:HGNC:13930|Ensembl:ENSG00000204536|Vega:OTTHUMG00000031112 +54536 EXOC6 MIM:609672|HGNC:HGNC:23196|Ensembl:ENSG00000138190|Vega:OTTHUMG00000018767 +54537 FAM35A HGNC:HGNC:28773|Ensembl:ENSG00000122376|Vega:OTTHUMG00000018669 +54538 ROBO4 MIM:607528|HGNC:HGNC:17985|Ensembl:ENSG00000154133|Vega:OTTHUMG00000165936 +54539 NDUFB11 MIM:300403|HGNC:HGNC:20372|Ensembl:ENSG00000147123|Vega:OTTHUMG00000021433 +54540 FAM193B MIM:615813|HGNC:HGNC:25524|Ensembl:ENSG00000146067|Vega:OTTHUMG00000163396 +54541 DDIT4 MIM:607729|HGNC:HGNC:24944|Ensembl:ENSG00000168209|Vega:OTTHUMG00000183961 +54542 RC3H2 MIM:615231|HGNC:HGNC:21461|Ensembl:ENSG00000056586|Vega:OTTHUMG00000020632 +54543 TOMM7 MIM:607980|HGNC:HGNC:21648|Ensembl:ENSG00000196683|Vega:OTTHUMG00000094805 +54544 CRCT1 MIM:617426|HGNC:HGNC:29875|Ensembl:ENSG00000169509|Vega:OTTHUMG00000012391 +54545 MTMR12 MIM:606501|HGNC:HGNC:18191|Ensembl:ENSG00000150712|Vega:OTTHUMG00000161978 +54546 RNF186 MIM:617163|HGNC:HGNC:25978|Ensembl:ENSG00000178828|Vega:OTTHUMG00000002709 +54549 SDK2 MIM:607217|HGNC:HGNC:19308|Ensembl:ENSG00000069188|Vega:OTTHUMG00000152726 +54550 NECAB2 HGNC:HGNC:23746|Ensembl:ENSG00000103154|Vega:OTTHUMG00000137636 +54551 MAGEL2 MIM:605283|HGNC:HGNC:6814|Ensembl:ENSG00000254585|Vega:OTTHUMG00000167582 +54552 GNL3L MIM:300873|HGNC:HGNC:25553|Ensembl:ENSG00000130119|Vega:OTTHUMG00000021629 +54553 LINC02486 HGNC:HGNC:25288|Ensembl:ENSG00000268471 +54554 WDR5B HGNC:HGNC:17826|Ensembl:ENSG00000196981|Vega:OTTHUMG00000159489 +54555 DDX49 HGNC:HGNC:18684|Ensembl:ENSG00000105671|Vega:OTTHUMG00000182994 +54556 ING3 MIM:607493|HGNC:HGNC:14587|Ensembl:ENSG00000071243|Vega:OTTHUMG00000141270 +54557 SGTB HGNC:HGNC:23567|Ensembl:ENSG00000197860|Vega:OTTHUMG00000097801 +54558 SPATA6 MIM:613947|HGNC:HGNC:18309|Ensembl:ENSG00000132122|Vega:OTTHUMG00000007794 +54566 EPB41L4B MIM:610340|HGNC:HGNC:19818|Ensembl:ENSG00000095203|Vega:OTTHUMG00000020470 +54567 DLL4 MIM:605185|HGNC:HGNC:2910|Ensembl:ENSG00000128917|Vega:OTTHUMG00000172511 +54568 UGT2B29P HGNC:HGNC:12552 +54569 UGT2B27P HGNC:HGNC:12551 +54570 UGT2B26P HGNC:HGNC:12550 +54571 UGT2B25P HGNC:HGNC:12549 +54572 UGT2B24P HGNC:HGNC:12548 +54573 UGT1A12P HGNC:HGNC:12533 +54574 UGT1A11P HGNC:HGNC:12532 +54575 UGT1A10 MIM:606435|HGNC:HGNC:12531|Ensembl:ENSG00000242515|Vega:OTTHUMG00000059121 +54576 UGT1A8 MIM:606433|HGNC:HGNC:12540|Ensembl:ENSG00000242366|Vega:OTTHUMG00000059123 +54577 UGT1A7 MIM:606432|HGNC:HGNC:12539|Ensembl:ENSG00000244122|Vega:OTTHUMG00000059004 +54578 UGT1A6 MIM:606431|HGNC:HGNC:12538|Ensembl:ENSG00000167165|Vega:OTTHUMG00000059122 +54579 UGT1A5 MIM:606430|HGNC:HGNC:12537|Ensembl:ENSG00000240224|Vega:OTTHUMG00000059120 +54580 UGT1A2P HGNC:HGNC:12534 +54581 SCAND2P MIM:610417|HGNC:HGNC:10567 +54583 EGLN1 MIM:606425|HGNC:HGNC:1232|Ensembl:ENSG00000135766|Vega:OTTHUMG00000038027 +54584 GNB1L MIM:610778|HGNC:HGNC:4397|Ensembl:ENSG00000185838|Vega:OTTHUMG00000150279 +54585 LZTFL1 MIM:606568|HGNC:HGNC:6741|Ensembl:ENSG00000163818|Vega:OTTHUMG00000133452 +54586 EQTN HGNC:HGNC:1359|Ensembl:ENSG00000120160|Vega:OTTHUMG00000021033 +54587 MXRA8 MIM:617293|HGNC:HGNC:7542|Ensembl:ENSG00000162576|Vega:OTTHUMG00000002973 +54596 L1TD1 HGNC:HGNC:25595|Ensembl:ENSG00000240563|Vega:OTTHUMG00000008914 +54600 UGT1A9 MIM:606434|HGNC:HGNC:12541|Ensembl:ENSG00000241119|Vega:OTTHUMG00000059124 +54602 NDFIP2 MIM:610041|HGNC:HGNC:18537|Ensembl:ENSG00000102471|Vega:OTTHUMG00000017136 +54606 DDX56 MIM:608023|HGNC:HGNC:18193|Ensembl:ENSG00000136271|Vega:OTTHUMG00000129211 +54617 INO80 MIM:610169|HGNC:HGNC:26956|Ensembl:ENSG00000128908|Vega:OTTHUMG00000130209 +54619 CCNJ HGNC:HGNC:23434|Ensembl:ENSG00000107443|Vega:OTTHUMG00000018823 +54620 FBXL19 MIM:609085|HGNC:HGNC:25300|Ensembl:ENSG00000099364|Vega:OTTHUMG00000132403 +54621 VSIG10 HGNC:HGNC:26078|Ensembl:ENSG00000176834|Vega:OTTHUMG00000168835 +54622 ARL15 HGNC:HGNC:25945|Ensembl:ENSG00000185305|Vega:OTTHUMG00000162287 +54623 PAF1 MIM:610506|HGNC:HGNC:25459|Ensembl:ENSG00000006712|Vega:OTTHUMG00000182968 +54625 PARP14 MIM:610028|HGNC:HGNC:29232|Ensembl:ENSG00000173193|Vega:OTTHUMG00000159552 +54626 HES2 MIM:609970|HGNC:HGNC:16005|Ensembl:ENSG00000069812|Vega:OTTHUMG00000000752 +54627 MAP10 HGNC:HGNC:29265|Ensembl:ENSG00000212916|Vega:OTTHUMG00000037819 +54629 MINDY2 HGNC:HGNC:26954|Ensembl:ENSG00000128923|Vega:OTTHUMG00000171983 +54657 UGT1A4 MIM:606429|HGNC:HGNC:12536|Ensembl:ENSG00000244474|Vega:OTTHUMG00000059119 +54658 UGT1A1 MIM:191740|HGNC:HGNC:12530|Ensembl:ENSG00000241635|Vega:OTTHUMG00000059117 +54659 UGT1A3 MIM:606428|HGNC:HGNC:12535|Ensembl:ENSG00000243135|Vega:OTTHUMG00000059118 +54660 PCDHB18P HGNC:HGNC:14548|Ensembl:ENSG00000146001 +54661 PCDHB17P HGNC:HGNC:14547|Ensembl:ENSG00000255622 +54662 TBC1D13 MIM:616218|HGNC:HGNC:25571|Ensembl:ENSG00000107021|Vega:OTTHUMG00000020760 +54663 WDR74 HGNC:HGNC:25529|Ensembl:ENSG00000133316|Vega:OTTHUMG00000167695 +54664 TMEM106B MIM:613413|HGNC:HGNC:22407|Ensembl:ENSG00000106460|Vega:OTTHUMG00000125537 +54665 RSBN1 MIM:615858|HGNC:HGNC:25642|Ensembl:ENSG00000081019|Vega:OTTHUMG00000011938 +54674 LRRN3 HGNC:HGNC:17200|Ensembl:ENSG00000173114|Vega:OTTHUMG00000155039 +54675 CRLS1 MIM:608188|HGNC:HGNC:16148|Ensembl:ENSG00000088766|Vega:OTTHUMG00000031823 +54676 GTPBP2 MIM:607434|HGNC:HGNC:4670|Ensembl:ENSG00000172432|Vega:OTTHUMG00000014744 +54677 CROT MIM:606090|HGNC:HGNC:2366|Ensembl:ENSG00000005469|Vega:OTTHUMG00000023653 +54680 ZNHIT6 HGNC:HGNC:26089|Ensembl:ENSG00000117174|Vega:OTTHUMG00000010576 +54681 P4HTM MIM:614584|HGNC:HGNC:28858|Ensembl:ENSG00000178467|Vega:OTTHUMG00000074057 +54682 MANSC1 HGNC:HGNC:25505|Ensembl:ENSG00000111261|Vega:OTTHUMG00000168541 +54700 RRN3 MIM:605121|HGNC:HGNC:30346|Ensembl:ENSG00000085721|Vega:OTTHUMG00000129847 +54704 PDP1 MIM:605993|HGNC:HGNC:9279|Ensembl:ENSG00000164951|Vega:OTTHUMG00000164356 +54707 GPN2 HGNC:HGNC:25513|Ensembl:ENSG00000142751|Vega:OTTHUMG00000004227 +54708 MARCH5 MIM:610637|HGNC:HGNC:26025|Ensembl:ENSG00000198060|Vega:OTTHUMG00000018757 +54714 CNGB3 MIM:605080|HGNC:HGNC:2153|Ensembl:ENSG00000170289|Vega:OTTHUMG00000163738 +54715 RBFOX1 MIM:605104|HGNC:HGNC:18222|Ensembl:ENSG00000078328|Vega:OTTHUMG00000129551 +54716 SLC6A20 MIM:605616|HGNC:HGNC:30927|Ensembl:ENSG00000163817|Vega:OTTHUMG00000133446 +54718 BTN2A3P MIM:613592|HGNC:HGNC:13229|Ensembl:ENSG00000124549 +54719 RNANC MIM:221900 +54726 OTUD4 MIM:611744|HGNC:HGNC:24949|Ensembl:ENSG00000164164|Vega:OTTHUMG00000161480 +54729 NKX1-1 HGNC:HGNC:24975|Ensembl:ENSG00000235608|Vega:OTTHUMG00000160165 +54732 TMED9 HGNC:HGNC:24878|Ensembl:ENSG00000184840|Vega:OTTHUMG00000130859 +54733 SLC35F2 HGNC:HGNC:23615|Ensembl:ENSG00000110660|Vega:OTTHUMG00000166366 +54734 RAB39A HGNC:HGNC:16521|Ensembl:ENSG00000179331|Vega:OTTHUMG00000166367 +54737 MPHOSPH8 MIM:611626|HGNC:HGNC:29810|Ensembl:ENSG00000196199|Vega:OTTHUMG00000016498 +54738 FEV MIM:607150|HGNC:HGNC:18562|Ensembl:ENSG00000163497|Vega:OTTHUMG00000133080 +54739 XAF1 MIM:606717|HGNC:HGNC:30932|Ensembl:ENSG00000132530|Vega:OTTHUMG00000177908 +54741 LEPROT MIM:613461|HGNC:HGNC:29477|Ensembl:ENSG00000213625|Vega:OTTHUMG00000009065 +54742 LY6K MIM:615093|HGNC:HGNC:24225|Ensembl:ENSG00000160886|Vega:OTTHUMG00000164720 +54748 LINC00527 HGNC:HGNC:17215 +54749 EPDR1 HGNC:HGNC:17572|Ensembl:ENSG00000086289|Vega:OTTHUMG00000102187 +54751 FBLIM1 MIM:607747|HGNC:HGNC:24686|Ensembl:ENSG00000162458|Vega:OTTHUMG00000003079 +54752 FNDC8 HGNC:HGNC:25286|Ensembl:ENSG00000073598|Vega:OTTHUMG00000132932 +54753 ZNF853 HGNC:HGNC:21767|Ensembl:ENSG00000236609|Vega:OTTHUMG00000151853 +54754 NUTM2F HGNC:HGNC:23450|Ensembl:ENSG00000130950|Vega:OTTHUMG00000020260 +54756 IL17RD MIM:606807|HGNC:HGNC:17616|Ensembl:ENSG00000144730|Vega:OTTHUMG00000150171 +54757 FAM20A MIM:611062|HGNC:HGNC:23015|Ensembl:ENSG00000108950|Vega:OTTHUMG00000180152 +54758 KLHDC4 HGNC:HGNC:25272|Ensembl:ENSG00000104731|Vega:OTTHUMG00000137657 +54760 PCSK4 MIM:600487|HGNC:HGNC:8746|Ensembl:ENSG00000115257|Vega:OTTHUMG00000128541 +54762 GRAMD1C HGNC:HGNC:25252|Ensembl:ENSG00000178075|Vega:OTTHUMG00000159340 +54763 ROPN1 MIM:611757|HGNC:HGNC:17692|Ensembl:ENSG00000065371|Vega:OTTHUMG00000159556 +54764 ZRANB1 MIM:611749|HGNC:HGNC:18224|Ensembl:ENSG00000019995|Vega:OTTHUMG00000019223 +54765 TRIM44 MIM:612298|HGNC:HGNC:19016|Ensembl:ENSG00000166326|Vega:OTTHUMG00000166312 +54766 BTG4 MIM:605673|HGNC:HGNC:13862|Ensembl:ENSG00000137707|Vega:OTTHUMG00000166718 +54768 HYDIN MIM:610812|HGNC:HGNC:19368|Ensembl:ENSG00000157423|Vega:OTTHUMG00000137584 +54769 DIRAS2 MIM:607863|HGNC:HGNC:19323|Ensembl:ENSG00000165023|Vega:OTTHUMG00000020196 +54776 PPP1R12C MIM:613245|HGNC:HGNC:14947|Ensembl:ENSG00000125503|Vega:OTTHUMG00000180540 +54777 CFAP46 HGNC:HGNC:25247|Ensembl:ENSG00000171811|Vega:OTTHUMG00000019292 +54778 RNF111 MIM:605840|HGNC:HGNC:17384|Ensembl:ENSG00000157450|Vega:OTTHUMG00000132716 +54780 NSMCE4A MIM:612987|HGNC:HGNC:25935|Ensembl:ENSG00000107672|Vega:OTTHUMG00000019180 +54784 ALKBH4 MIM:613302|HGNC:HGNC:21900|Ensembl:ENSG00000160993|Vega:OTTHUMG00000157720 +54785 BORCS6 MIM:616599|HGNC:HGNC:25939|Ensembl:ENSG00000196544|Vega:OTTHUMG00000153930 +54788 DNAJB12 MIM:608376|HGNC:HGNC:14891|Ensembl:ENSG00000148719|Vega:OTTHUMG00000018436 +54790 TET2 MIM:612839|HGNC:HGNC:25941|Ensembl:ENSG00000168769|Vega:OTTHUMG00000131213 +54793 KCTD9 MIM:617265|HGNC:HGNC:22401|Ensembl:ENSG00000104756|Vega:OTTHUMG00000099428 +54795 TRPM4 MIM:606936|HGNC:HGNC:17993|Ensembl:ENSG00000130529|Vega:OTTHUMG00000183184 +54796 BNC2 MIM:608669|HGNC:HGNC:30988|Ensembl:ENSG00000173068|Vega:OTTHUMG00000019593 +54797 MED18 MIM:612384|HGNC:HGNC:25944|Ensembl:ENSG00000130772|Vega:OTTHUMG00000003537 +54798 DCHS2 MIM:612486|HGNC:HGNC:23111|Ensembl:ENSG00000197410|Vega:OTTHUMG00000161556 +54799 MBTD1 HGNC:HGNC:19866|Ensembl:ENSG00000011258|Vega:OTTHUMG00000150442 +54800 KLHL24 MIM:611295|HGNC:HGNC:25947|Ensembl:ENSG00000114796|Vega:OTTHUMG00000156911 +54801 HAUS6 MIM:613433|HGNC:HGNC:25948|Ensembl:ENSG00000147874|Vega:OTTHUMG00000019622 +54802 TRIT1 HGNC:HGNC:20286|Ensembl:ENSG00000043514|Vega:OTTHUMG00000009245 +54805 CNNM2 MIM:607803|HGNC:HGNC:103|Ensembl:ENSG00000148842|Vega:OTTHUMG00000018976 +54806 AHI1 MIM:608894|HGNC:HGNC:21575|Ensembl:ENSG00000135541|Vega:OTTHUMG00000015631 +54807 ZNF586 HGNC:HGNC:25949|Ensembl:ENSG00000083828|Vega:OTTHUMG00000183477 +54808 DYM MIM:607461|HGNC:HGNC:21317|Ensembl:ENSG00000141627|Vega:OTTHUMG00000132659 +54809 SAMD9 MIM:610456|HGNC:HGNC:1348|Ensembl:ENSG00000205413|Vega:OTTHUMG00000155809 +54810 GIPC2 HGNC:HGNC:18177|Ensembl:ENSG00000137960|Vega:OTTHUMG00000041145 +54811 ZNF562 HGNC:HGNC:25950|Ensembl:ENSG00000171466|Vega:OTTHUMG00000180205 +54812 AFTPH HGNC:HGNC:25951|Ensembl:ENSG00000119844|Vega:OTTHUMG00000129539 +54813 KLHL28 HGNC:HGNC:19741|Ensembl:ENSG00000179454|Vega:OTTHUMG00000140263 +54814 QPCTL HGNC:HGNC:25952|Ensembl:ENSG00000011478|Vega:OTTHUMG00000182131 +54815 GATAD2A MIM:614997|HGNC:HGNC:29989|Ensembl:ENSG00000167491|Vega:OTTHUMG00000152541 +54816 ZNF280D HGNC:HGNC:25953|Ensembl:ENSG00000137871|Vega:OTTHUMG00000172509 +54819 ZCCHC10 HGNC:HGNC:25954|Ensembl:ENSG00000155329|Vega:OTTHUMG00000129013 +54820 NDE1 MIM:609449|HGNC:HGNC:17619|Ensembl:ENSG00000072864|Vega:OTTHUMG00000129885 +54821 ERCC6L MIM:300687|HGNC:HGNC:20794|Ensembl:ENSG00000186871|Vega:OTTHUMG00000021810 +54822 TRPM7 MIM:605692|HGNC:HGNC:17994|Ensembl:ENSG00000092439|Vega:OTTHUMG00000172449 +54823 SWT1 HGNC:HGNC:16785|Ensembl:ENSG00000116668|Vega:OTTHUMG00000035390 +54825 CDHR2 HGNC:HGNC:18231|Ensembl:ENSG00000074276|Vega:OTTHUMG00000163229 +54826 GIN1 HGNC:HGNC:25959|Ensembl:ENSG00000145723|Vega:OTTHUMG00000162811 +54827 NXPE4 HGNC:HGNC:23117|Ensembl:ENSG00000137634|Vega:OTTHUMG00000168291 +54828 BCAS3 MIM:607470|HGNC:HGNC:14347|Ensembl:ENSG00000141376|Vega:OTTHUMG00000180064 +54829 ASPN MIM:608135|HGNC:HGNC:14872|Ensembl:ENSG00000106819|Vega:OTTHUMG00000020227 +54830 NUP62CL HGNC:HGNC:25960|Ensembl:ENSG00000198088|Vega:OTTHUMG00000022159 +54831 BEST2 MIM:607335|HGNC:HGNC:17107|Ensembl:ENSG00000039987|Vega:OTTHUMG00000169293 +54832 VPS13C MIM:608879|HGNC:HGNC:23594|Ensembl:ENSG00000129003|Vega:OTTHUMG00000132801 +54834 GDAP2 HGNC:HGNC:18010|Ensembl:ENSG00000196505|Vega:OTTHUMG00000012199 +54836 BSPRY HGNC:HGNC:18232|Ensembl:ENSG00000119411|Vega:OTTHUMG00000021006 +54838 WBP1L MIM:611129|HGNC:HGNC:23510|Ensembl:ENSG00000166272|Vega:OTTHUMG00000018968 +54839 LRRC49 HGNC:HGNC:25965|Ensembl:ENSG00000137821|Vega:OTTHUMG00000172182 +54840 APTX MIM:606350|HGNC:HGNC:15984|Ensembl:ENSG00000137074|Vega:OTTHUMG00000019759 +54841 BIVM HGNC:HGNC:16034|Ensembl:ENSG00000134897|Vega:OTTHUMG00000017309 +54842 MFSD6 MIM:613476|HGNC:HGNC:24711|Ensembl:ENSG00000151690|Vega:OTTHUMG00000132671 +54843 SYTL2 MIM:612880|HGNC:HGNC:15585|Ensembl:ENSG00000137501|Vega:OTTHUMG00000166977 +54845 ESRP1 MIM:612959|HGNC:HGNC:25966|Ensembl:ENSG00000104413|Vega:OTTHUMG00000164587 +54847 SIDT1 MIM:606816|HGNC:HGNC:25967|Ensembl:ENSG00000072858|Vega:OTTHUMG00000159299 +54848 ARHGEF38 HGNC:HGNC:25968|Ensembl:ENSG00000236699|Vega:OTTHUMG00000154752 +54849 DEF8 HGNC:HGNC:25969|Ensembl:ENSG00000140995|Vega:OTTHUMG00000138989 +54850 FBXL12 MIM:609079|HGNC:HGNC:13611|Ensembl:ENSG00000127452|Vega:OTTHUMG00000180212 +54851 ANKRD49 HGNC:HGNC:25970|Ensembl:ENSG00000168876|Vega:OTTHUMG00000167793 +54852 PAQR5 MIM:607781|HGNC:HGNC:29645|Ensembl:ENSG00000137819|Vega:OTTHUMG00000133322 +54853 WDR55 HGNC:HGNC:25971|Ensembl:ENSG00000120314|Vega:OTTHUMG00000129506 +54854 FAM83E HGNC:HGNC:25972|Ensembl:ENSG00000105523|Vega:OTTHUMG00000183315 +54855 FAM46C MIM:613952|HGNC:HGNC:24712|Ensembl:ENSG00000183508|Vega:OTTHUMG00000013703 +54856 GON4L MIM:610393|HGNC:HGNC:25973|Ensembl:ENSG00000116580|Vega:OTTHUMG00000014106 +54857 GDPD2 MIM:300940|HGNC:HGNC:25974|Ensembl:ENSG00000130055|Vega:OTTHUMG00000021776 +54858 PGPEP1 MIM:610694|HGNC:HGNC:13568|Ensembl:ENSG00000130517|Vega:OTTHUMG00000183358 +54859 ELP6 MIM:615020|HGNC:HGNC:25976|Ensembl:ENSG00000163832|Vega:OTTHUMG00000133521 +54860 MS4A12 MIM:606550|HGNC:HGNC:13370|Ensembl:ENSG00000071203|Vega:OTTHUMG00000165364 +54861 SNRK MIM:612760|HGNC:HGNC:30598|Ensembl:ENSG00000163788|Vega:OTTHUMG00000156491 +54862 CC2D1A MIM:610055|HGNC:HGNC:30237|Ensembl:ENSG00000132024|Vega:OTTHUMG00000181852 +54863 TOR4A HGNC:HGNC:25981|Ensembl:ENSG00000198113|Vega:OTTHUMG00000131779 +54865 GPATCH4 HGNC:HGNC:25982|Ensembl:ENSG00000160818|Vega:OTTHUMG00000033203 +54866 PPP1R14D MIM:613256|HGNC:HGNC:14953|Ensembl:ENSG00000166143|Vega:OTTHUMG00000130064 +54867 TMEM214 MIM:615301|HGNC:HGNC:25983|Ensembl:ENSG00000119777|Vega:OTTHUMG00000151999 +54868 TMEM104 HGNC:HGNC:25984|Ensembl:ENSG00000109066|Vega:OTTHUMG00000179025 +54869 EPS8L1 MIM:614987|HGNC:HGNC:21295|Ensembl:ENSG00000131037|Vega:OTTHUMG00000180513 +54870 QRICH1 MIM:617387|HGNC:HGNC:24713|Ensembl:ENSG00000198218|Vega:OTTHUMG00000156772 +54872 PIGG MIM:616918|HGNC:HGNC:25985|Ensembl:ENSG00000174227|Vega:OTTHUMG00000112457 +54873 PALMD MIM:610182|HGNC:HGNC:15846|Ensembl:ENSG00000099260|Vega:OTTHUMG00000010764 +54874 FNBP1L MIM:608848|HGNC:HGNC:20851|Ensembl:ENSG00000137942|Vega:OTTHUMG00000010863 +54875 CNTLN MIM:611870|HGNC:HGNC:23432|Ensembl:ENSG00000044459|Vega:OTTHUMG00000019599 +54876 DCAF16 HGNC:HGNC:25987|Ensembl:ENSG00000163257|Vega:OTTHUMG00000128536 +54877 ZCCHC2 HGNC:HGNC:22916|Ensembl:ENSG00000141664|Vega:OTTHUMG00000180165 +54878 DPP8 MIM:606819|HGNC:HGNC:16490|Ensembl:ENSG00000074603|Vega:OTTHUMG00000133150 +54879 ST7L HGNC:HGNC:18441|Ensembl:ENSG00000007341|Vega:OTTHUMG00000011753 +54880 BCOR MIM:300485|HGNC:HGNC:20893|Ensembl:ENSG00000183337|Vega:OTTHUMG00000024100 +54881 TEX10 MIM:616717|HGNC:HGNC:25988|Ensembl:ENSG00000136891|Vega:OTTHUMG00000020366 +54882 ANKHD1 MIM:610500|HGNC:HGNC:24714|Ensembl:ENSG00000131503|Vega:OTTHUMG00000161610 +54883 CWC25 HGNC:HGNC:25989|Ensembl:ENSG00000273559|Vega:OTTHUMG00000188505 +54884 RETSAT HGNC:HGNC:25991|Ensembl:ENSG00000042445|Vega:OTTHUMG00000154611 +54885 TBC1D8B HGNC:HGNC:24715|Ensembl:ENSG00000133138|Vega:OTTHUMG00000022152 +54886 PLPPR1 HGNC:HGNC:25993|Ensembl:ENSG00000148123|Vega:OTTHUMG00000020373 +54887 UHRF1BP1 HGNC:HGNC:21216|Ensembl:ENSG00000065060|Vega:OTTHUMG00000014557 +54888 NSUN2 MIM:610916|HGNC:HGNC:25994|Ensembl:ENSG00000037474|Vega:OTTHUMG00000090455 +54890 ALKBH5 MIM:613303|HGNC:HGNC:25996|Ensembl:ENSG00000091542|Vega:OTTHUMG00000059397 +54891 INO80D HGNC:HGNC:25997|Ensembl:ENSG00000114933|Vega:OTTHUMG00000154649 +54892 NCAPG2 MIM:608532|HGNC:HGNC:21904|Ensembl:ENSG00000146918|Vega:OTTHUMG00000151438 +54893 MTMR10 HGNC:HGNC:25999|Ensembl:ENSG00000166912|Vega:OTTHUMG00000175662 +54894 RNF43 MIM:612482|HGNC:HGNC:18505|Ensembl:ENSG00000108375|Vega:OTTHUMG00000179077 +54896 PQLC2 MIM:614760|HGNC:HGNC:26001|Ensembl:ENSG00000040487|Vega:OTTHUMG00000002521 +54897 CASZ1 MIM:609895|HGNC:HGNC:26002|Ensembl:ENSG00000130940|Vega:OTTHUMG00000002035 +54898 ELOVL2 MIM:611814|HGNC:HGNC:14416|Ensembl:ENSG00000197977|Vega:OTTHUMG00000014252 +54899 PXK MIM:611450|HGNC:HGNC:23326|Ensembl:ENSG00000168297|Vega:OTTHUMG00000159149 +54900 LAX1 HGNC:HGNC:26005|Ensembl:ENSG00000122188|Vega:OTTHUMG00000035908 +54901 CDKAL1 MIM:611259|HGNC:HGNC:21050|Ensembl:ENSG00000145996|Vega:OTTHUMG00000014340 +54902 TTC19 MIM:613814|HGNC:HGNC:26006|Ensembl:ENSG00000011295|Vega:OTTHUMG00000059306 +54903 MKS1 MIM:609883|HGNC:HGNC:7121|Ensembl:ENSG00000011143|Vega:OTTHUMG00000133714 +54904 NSD3 MIM:607083|HGNC:HGNC:12767|Ensembl:ENSG00000147548|Vega:OTTHUMG00000165115 +54905 CYP2W1 MIM:615967|HGNC:HGNC:20243|Ensembl:ENSG00000073067|Vega:OTTHUMG00000074071 +54906 FAM208B HGNC:HGNC:23484|Ensembl:ENSG00000108021|Vega:OTTHUMG00000017605 +54908 SPDL1 MIM:616401|HGNC:HGNC:26010|Ensembl:ENSG00000040275|Vega:OTTHUMG00000130438 +54910 SEMA4C MIM:604462|HGNC:HGNC:10731|Ensembl:ENSG00000168758|Vega:OTTHUMG00000130535 +54913 RPP25 HGNC:HGNC:30361|Ensembl:ENSG00000178718|Vega:OTTHUMG00000142822 +54914 FOCAD MIM:614606|HGNC:HGNC:23377|Ensembl:ENSG00000188352|Vega:OTTHUMG00000066930 +54915 YTHDF1 MIM:616529|HGNC:HGNC:15867|Ensembl:ENSG00000149658|Vega:OTTHUMG00000032955 +54916 TMEM260 MIM:617449|HGNC:HGNC:20185|Ensembl:ENSG00000070269|Vega:OTTHUMG00000152337 +54918 CMTM6 MIM:607889|HGNC:HGNC:19177|Ensembl:ENSG00000091317|Vega:OTTHUMG00000130747 +54919 DNAAF5 MIM:614864|HGNC:HGNC:26013|Ensembl:ENSG00000164818|Vega:OTTHUMG00000151416 +54920 DUS2 MIM:609707|HGNC:HGNC:26014|Ensembl:ENSG00000167264|Vega:OTTHUMG00000137538 +54921 CHTF8 MIM:613202|HGNC:HGNC:24353|Ensembl:ENSG00000168802|Vega:OTTHUMG00000163909 +54922 RASIP1 MIM:609623|HGNC:HGNC:24716|Ensembl:ENSG00000105538|Vega:OTTHUMG00000183323 +54923 LIME1 MIM:609809|HGNC:HGNC:26016|Ensembl:ENSG00000203896|Vega:OTTHUMG00000032999 +54925 ZSCAN32 HGNC:HGNC:20812|Ensembl:ENSG00000140987|Vega:OTTHUMG00000129357 +54926 UBE2R2 MIM:612506|HGNC:HGNC:19907|Ensembl:ENSG00000107341|Vega:OTTHUMG00000019797 +54927 CHCHD3 MIM:613748|HGNC:HGNC:21906|Ensembl:ENSG00000106554|Vega:OTTHUMG00000155231 +54928 IMPAD1 MIM:614010|HGNC:HGNC:26019|Ensembl:ENSG00000104331|Vega:OTTHUMG00000164415 +54929 TMEM161A HGNC:HGNC:26020|Ensembl:ENSG00000064545|Vega:OTTHUMG00000182217 +54930 HAUS4 MIM:613431|HGNC:HGNC:20163|Ensembl:ENSG00000092036|Vega:OTTHUMG00000028710 +54931 TRMT10C MIM:615423|HGNC:HGNC:26022|Ensembl:ENSG00000174173|Vega:OTTHUMG00000159114 +54932 EXD3 HGNC:HGNC:26023|Ensembl:ENSG00000187609|Vega:OTTHUMG00000156149 +54933 RHBDL2 MIM:608962|HGNC:HGNC:16083|Ensembl:ENSG00000158315|Vega:OTTHUMG00000000487 +54934 KANSL2 MIM:615488|HGNC:HGNC:26024|Ensembl:ENSG00000139620|Vega:OTTHUMG00000170392 +54935 DUSP23 HGNC:HGNC:21480|Ensembl:ENSG00000158716|Vega:OTTHUMG00000022795 +54936 ADPRHL2 MIM:610624|HGNC:HGNC:21304|Ensembl:ENSG00000116863|Vega:OTTHUMG00000007628 +54937 SOHLH2 MIM:616066|HGNC:HGNC:26026|Ensembl:ENSG00000120669|Vega:OTTHUMG00000016728 +54938 SARS2 MIM:612804|HGNC:HGNC:17697|Ensembl:ENSG00000104835|Vega:OTTHUMG00000182691 +54939 COMMD4 MIM:616701|HGNC:HGNC:26027|Ensembl:ENSG00000140365|Vega:OTTHUMG00000142823 +54940 OCIAD1 HGNC:HGNC:16074|Ensembl:ENSG00000109180|Vega:OTTHUMG00000102095 +54941 RNF125 MIM:610432|HGNC:HGNC:21150|Ensembl:ENSG00000101695|Vega:OTTHUMG00000132266 +54942 FAM206A HGNC:HGNC:1364|Ensembl:ENSG00000119328|Vega:OTTHUMG00000020467 +54943 DNAJC28 HGNC:HGNC:1297|Ensembl:ENSG00000177692|Vega:OTTHUMG00000065531 +54944 LINC01521 HGNC:HGNC:26029 +54946 SLC41A3 MIM:610803|HGNC:HGNC:31046|Ensembl:ENSG00000114544|Vega:OTTHUMG00000162678 +54947 LPCAT2 MIM:612040|HGNC:HGNC:26032|Ensembl:ENSG00000087253|Vega:OTTHUMG00000133238 +54948 MRPL16 MIM:611829|HGNC:HGNC:14476|Ensembl:ENSG00000166902|Vega:OTTHUMG00000167410 +54949 SDHAF2 MIM:613019|HGNC:HGNC:26034|Ensembl:ENSG00000167985|Ensembl:ENSG00000256591|Vega:OTTHUMG00000168148|Vega:OTTHUMG00000168279 +54951 COMMD8 MIM:616656|HGNC:HGNC:26036|Ensembl:ENSG00000169019|Vega:OTTHUMG00000099435 +54952 TRNAU1AP HGNC:HGNC:30813|Ensembl:ENSG00000180098|Vega:OTTHUMG00000003653 +54953 C1orf27 MIM:609335|HGNC:HGNC:24299|Ensembl:ENSG00000157181|Vega:OTTHUMG00000035579 +54954 FAM120C MIM:300741|HGNC:HGNC:16949|Ensembl:ENSG00000184083|Vega:OTTHUMG00000021625 +54955 C1orf109 MIM:614799|HGNC:HGNC:26039|Ensembl:ENSG00000116922|Vega:OTTHUMG00000004323 +54956 PARP16 HGNC:HGNC:26040|Ensembl:ENSG00000138617|Vega:OTTHUMG00000133138 +54957 TXNL4B HGNC:HGNC:26041|Ensembl:ENSG00000140830|Vega:OTTHUMG00000173453 +54958 TMEM160 HGNC:HGNC:26042|Ensembl:ENSG00000130748|Vega:OTTHUMG00000183441 +54959 ODAM MIM:614843|HGNC:HGNC:26043|Ensembl:ENSG00000109205|Vega:OTTHUMG00000129406 +54960 GEMIN8 MIM:300962|HGNC:HGNC:26044|Ensembl:ENSG00000046647|Vega:OTTHUMG00000021160 +54961 SSH3 MIM:606780|HGNC:HGNC:30581|Ensembl:ENSG00000172830|Vega:OTTHUMG00000167105 +54962 TIPIN MIM:610716|HGNC:HGNC:30750|Ensembl:ENSG00000075131|Vega:OTTHUMG00000133188 +54963 UCKL1 MIM:610866|HGNC:HGNC:15938|Ensembl:ENSG00000198276|Vega:OTTHUMG00000033003 +54964 C1orf56 HGNC:HGNC:26045|Ensembl:ENSG00000143443|Vega:OTTHUMG00000035159 +54965 PIGX MIM:610276|HGNC:HGNC:26046|Ensembl:ENSG00000163964|Vega:OTTHUMG00000155535 +54967 CT55 HGNC:HGNC:26047|Ensembl:ENSG00000169551|Vega:OTTHUMG00000022473 +54968 TMEM70 MIM:612418|HGNC:HGNC:26050|Ensembl:ENSG00000175606|Vega:OTTHUMG00000164502 +54969 HPF1 MIM:616614|HGNC:HGNC:26051|Ensembl:ENSG00000056050|Vega:OTTHUMG00000160960 +54970 TTC12 MIM:610732|HGNC:HGNC:23700|Ensembl:ENSG00000149292|Vega:OTTHUMG00000142832 +54971 BANP MIM:611564|HGNC:HGNC:13450|Ensembl:ENSG00000172530|Vega:OTTHUMG00000137678 +54972 TMEM132A MIM:617363|HGNC:HGNC:31092|Ensembl:ENSG00000006118|Vega:OTTHUMG00000167803 +54973 INTS11 MIM:611354|HGNC:HGNC:26052|Ensembl:ENSG00000127054|Vega:OTTHUMG00000003330 +54974 THG1L HGNC:HGNC:26053|Ensembl:ENSG00000113272|Vega:OTTHUMG00000130254 +54976 C20orf27 HGNC:HGNC:15873|Ensembl:ENSG00000101220|Vega:OTTHUMG00000031753 +54977 SLC25A38 MIM:610819|HGNC:HGNC:26054|Ensembl:ENSG00000144659|Vega:OTTHUMG00000131289 +54978 SLC35F6 HGNC:HGNC:26055|Ensembl:ENSG00000213699|Vega:OTTHUMG00000128407 +54979 HRASLS2 MIM:613866|HGNC:HGNC:17824|Ensembl:ENSG00000133328|Vega:OTTHUMG00000167851 +54980 C2orf42 HGNC:HGNC:26056|Ensembl:ENSG00000115998|Vega:OTTHUMG00000129642 +54981 NMRK1 MIM:608704|HGNC:HGNC:26057|Ensembl:ENSG00000106733|Vega:OTTHUMG00000020034 +54982 CLN6 MIM:606725|HGNC:HGNC:2077|Ensembl:ENSG00000128973|Vega:OTTHUMG00000133286 +54984 PINX1 MIM:606505|HGNC:HGNC:30046|Ensembl:ENSG00000254093|Vega:OTTHUMG00000163808 +54985 HCFC1R1 HGNC:HGNC:21198|Ensembl:ENSG00000103145|Vega:OTTHUMG00000177450 +54986 ULK4 MIM:617010|HGNC:HGNC:15784|Ensembl:ENSG00000168038|Vega:OTTHUMG00000156210 +54987 C1orf123 HGNC:HGNC:26059|Ensembl:ENSG00000162384|Vega:OTTHUMG00000008940 +54988 ACSM5 MIM:614361|HGNC:HGNC:26060|Ensembl:ENSG00000183549|Vega:OTTHUMG00000131551 +54989 ZNF770 HGNC:HGNC:26061|Ensembl:ENSG00000198146|Vega:OTTHUMG00000129689 +54991 C1orf159 HGNC:HGNC:26062|Ensembl:ENSG00000131591|Vega:OTTHUMG00000000745 +54993 ZSCAN2 HGNC:HGNC:20994|Ensembl:ENSG00000176371|Vega:OTTHUMG00000074027 +54994 GID8 MIM:611625|HGNC:HGNC:15857|Ensembl:ENSG00000101193|Vega:OTTHUMG00000032949 +54995 OXSM MIM:610324|HGNC:HGNC:26063|Ensembl:ENSG00000151093|Vega:OTTHUMG00000130477 +54996 MARC2 MIM:614127|HGNC:HGNC:26064|Ensembl:ENSG00000117791|Vega:OTTHUMG00000037354 +54997 TESC MIM:611585|HGNC:HGNC:26065|Ensembl:ENSG00000088992|Vega:OTTHUMG00000144168 +54998 AURKAIP1 MIM:609183|HGNC:HGNC:24114|Ensembl:ENSG00000175756|Vega:OTTHUMG00000001413 +55000 TUG1 MIM:614971|HGNC:HGNC:26066 +55001 TTC22 HGNC:HGNC:26067|Ensembl:ENSG00000006555|Vega:OTTHUMG00000009916 +55002 TMCO3 MIM:617134|HGNC:HGNC:20329|Ensembl:ENSG00000150403|Vega:OTTHUMG00000017389 +55003 PAK1IP1 MIM:607811|HGNC:HGNC:20882|Ensembl:ENSG00000111845|Vega:OTTHUMG00000014245 +55004 LAMTOR1 MIM:613510|HGNC:HGNC:26068|Ensembl:ENSG00000149357|Vega:OTTHUMG00000167869 +55005 RMND1 MIM:614917|HGNC:HGNC:21176|Ensembl:ENSG00000155906|Vega:OTTHUMG00000015837 +55006 TRMT61B HGNC:HGNC:26070|Ensembl:ENSG00000171103|Vega:OTTHUMG00000128433 +55007 FAM118A HGNC:HGNC:1313|Ensembl:ENSG00000100376|Vega:OTTHUMG00000151338 +55008 HERC6 MIM:609249|HGNC:HGNC:26072|Ensembl:ENSG00000138642|Vega:OTTHUMG00000160983 +55009 C19orf24 HGNC:HGNC:26073|Ensembl:ENSG00000228300|Vega:OTTHUMG00000153928 +55010 PARPBP MIM:613687|HGNC:HGNC:26074|Ensembl:ENSG00000185480|Vega:OTTHUMG00000167923 +55011 PIH1D1 MIM:611480|HGNC:HGNC:26075|Ensembl:ENSG00000104872|Vega:OTTHUMG00000183167 +55012 PPP2R3C MIM:615902|HGNC:HGNC:17485|Ensembl:ENSG00000092020|Vega:OTTHUMG00000140224 +55013 MCUB HGNC:HGNC:26076|Ensembl:ENSG00000005059|Vega:OTTHUMG00000161103 +55014 STX17 MIM:604204|HGNC:HGNC:11432|Ensembl:ENSG00000136874|Vega:OTTHUMG00000020359 +55015 PRPF39 MIM:614907|HGNC:HGNC:20314|Ensembl:ENSG00000185246|Vega:OTTHUMG00000140265 +55016 MARCH1 MIM:613331|HGNC:HGNC:26077|Ensembl:ENSG00000145416|Vega:OTTHUMG00000161204 +55017 C14orf119 HGNC:HGNC:20270|Ensembl:ENSG00000179933|Vega:OTTHUMG00000028717 +55018 LINC00483 HGNC:HGNC:26080|Ensembl:ENSG00000167117 +55020 TTC38 HGNC:HGNC:26082|Ensembl:ENSG00000075234|Vega:OTTHUMG00000150494 +55022 PID1 MIM:612930|HGNC:HGNC:26084|Ensembl:ENSG00000153823|Vega:OTTHUMG00000133191 +55023 PHIP MIM:612870|HGNC:HGNC:15673|Ensembl:ENSG00000146247|Vega:OTTHUMG00000015071 +55024 BANK1 MIM:610292|HGNC:HGNC:18233|Ensembl:ENSG00000153064|Vega:OTTHUMG00000160958 +55025 FLJ20712 - +55026 TMEM255A HGNC:HGNC:26086|Ensembl:ENSG00000125355|Vega:OTTHUMG00000022298 +55027 HEATR3 MIM:614951|HGNC:HGNC:26087|Ensembl:ENSG00000155393|Vega:OTTHUMG00000133174 +55028 C17orf80 HGNC:HGNC:29601|Ensembl:ENSG00000141219|Vega:OTTHUMG00000178417 +55030 FBXO34 MIM:609104|HGNC:HGNC:20201|Ensembl:ENSG00000178974|Vega:OTTHUMG00000171033 +55031 USP47 MIM:614460|HGNC:HGNC:20076|Ensembl:ENSG00000170242|Vega:OTTHUMG00000165685 +55032 SLC35A5 HGNC:HGNC:20792|Ensembl:ENSG00000138459|Vega:OTTHUMG00000159263 +55033 FKBP14 MIM:614505|HGNC:HGNC:18625|Ensembl:ENSG00000106080|Vega:OTTHUMG00000023442 +55034 MOCOS MIM:613274|HGNC:HGNC:18234|Ensembl:ENSG00000075643|Vega:OTTHUMG00000132590 +55035 NOL8 MIM:611534|HGNC:HGNC:23387|Ensembl:ENSG00000198000|Vega:OTTHUMG00000020221 +55036 CCDC40 MIM:613799|HGNC:HGNC:26090|Ensembl:ENSG00000141519|Vega:OTTHUMG00000132707 +55037 PTCD3 MIM:614918|HGNC:HGNC:24717|Ensembl:ENSG00000132300|Vega:OTTHUMG00000153168 +55038 CDCA4 MIM:612270|HGNC:HGNC:14625|Ensembl:ENSG00000170779|Vega:OTTHUMG00000170767 +55039 TRMT12 MIM:611244|HGNC:HGNC:26091|Ensembl:ENSG00000183665|Vega:OTTHUMG00000165022 +55040 EPN3 MIM:607264|HGNC:HGNC:18235|Ensembl:ENSG00000049283|Vega:OTTHUMG00000162155 +55041 PLEKHB2 HGNC:HGNC:19236|Ensembl:ENSG00000115762|Vega:OTTHUMG00000131656 +55048 VPS37C MIM:610038|HGNC:HGNC:26097|Ensembl:ENSG00000167987|Vega:OTTHUMG00000167826 +55049 C19orf60 HGNC:HGNC:26098|Ensembl:ENSG00000006015|Vega:OTTHUMG00000183112 +55051 NRDE2 HGNC:HGNC:20186|Ensembl:ENSG00000119720|Vega:OTTHUMG00000171020 +55052 MRPL20 MIM:611833|HGNC:HGNC:14478|Ensembl:ENSG00000242485|Vega:OTTHUMG00000002916 +55054 ATG16L1 MIM:610767|HGNC:HGNC:21498|Ensembl:ENSG00000085978 +55055 ZWILCH MIM:609984|HGNC:HGNC:25468|Ensembl:ENSG00000174442|Vega:OTTHUMG00000133194 +55056 GABPB1-IT1 HGNC:HGNC:25469|Ensembl:ENSG00000104064 +55057 CRYBG2 HGNC:HGNC:17295|Ensembl:ENSG00000176092 +55061 SUSD4 MIM:615827|HGNC:HGNC:25470|Ensembl:ENSG00000143502|Vega:OTTHUMG00000037936 +55062 WIPI1 MIM:609224|HGNC:HGNC:25471|Ensembl:ENSG00000070540|Vega:OTTHUMG00000179873 +55063 ZCWPW1 HGNC:HGNC:23486|Ensembl:ENSG00000078487|Vega:OTTHUMG00000159537 +55064 SPATA6L HGNC:HGNC:25472|Ensembl:ENSG00000106686|Vega:OTTHUMG00000019469 +55065 SLC52A1 MIM:607883|HGNC:HGNC:30225|Ensembl:ENSG00000132517|Vega:OTTHUMG00000099448 +55066 PDPR HGNC:HGNC:30264|Ensembl:ENSG00000090857|Vega:OTTHUMG00000176963 +55068 ENOX1 MIM:610914|HGNC:HGNC:25474|Ensembl:ENSG00000120658|Vega:OTTHUMG00000016818 +55069 TMEM248 HGNC:HGNC:25476|Ensembl:ENSG00000106609|Vega:OTTHUMG00000129553 +55070 DET1 MIM:608727|HGNC:HGNC:25477|Ensembl:ENSG00000140543|Vega:OTTHUMG00000171851 +55071 C9orf40 HGNC:HGNC:23433|Ensembl:ENSG00000135045|Vega:OTTHUMG00000020031 +55072 RNF31 MIM:612487|HGNC:HGNC:16031|Ensembl:ENSG00000092098|Vega:OTTHUMG00000028798 +55073 LRRC37A4P HGNC:HGNC:25479 +55074 OXR1 MIM:605609|HGNC:HGNC:15822|Ensembl:ENSG00000164830|Vega:OTTHUMG00000167682 +55075 UACA MIM:612516|HGNC:HGNC:15947|Ensembl:ENSG00000137831|Vega:OTTHUMG00000133363 +55076 TMEM45A MIM:616928|HGNC:HGNC:25480|Ensembl:ENSG00000181458|Vega:OTTHUMG00000150327 +55079 FEZF2 MIM:607414|HGNC:HGNC:13506|Ensembl:ENSG00000153266|Vega:OTTHUMG00000158705 +55080 TAPBPL MIM:607081|HGNC:HGNC:30683|Ensembl:ENSG00000139192|Vega:OTTHUMG00000168317 +55081 IFT57 MIM:606621|HGNC:HGNC:17367|Ensembl:ENSG00000114446|Vega:OTTHUMG00000159223 +55082 ARGLU1 MIM:614046|HGNC:HGNC:25482|Ensembl:ENSG00000134884|Vega:OTTHUMG00000017321 +55083 KIF26B MIM:614026|HGNC:HGNC:25484|Ensembl:ENSG00000162849|Vega:OTTHUMG00000040079 +55084 SOBP MIM:613667|HGNC:HGNC:29256|Ensembl:ENSG00000112320|Vega:OTTHUMG00000015312 +55086 CXorf57 HGNC:HGNC:25486|Ensembl:ENSG00000147231|Vega:OTTHUMG00000022150 +55088 CCDC186 HGNC:HGNC:24349|Ensembl:ENSG00000165813|Vega:OTTHUMG00000019081 +55089 SLC38A4 MIM:608065|HGNC:HGNC:14679|Ensembl:ENSG00000139209|Vega:OTTHUMG00000169518 +55090 MED9 MIM:609878|HGNC:HGNC:25487|Ensembl:ENSG00000141026|Vega:OTTHUMG00000059293 +55092 TMEM51 HGNC:HGNC:25488|Ensembl:ENSG00000171729|Vega:OTTHUMG00000002046 +55093 WDYHV1 HGNC:HGNC:25490|Ensembl:ENSG00000156795|Vega:OTTHUMG00000165093 +55094 GPATCH1 HGNC:HGNC:24658|Ensembl:ENSG00000076650|Vega:OTTHUMG00000180341 +55095 SAMD4B HGNC:HGNC:25492|Ensembl:ENSG00000179134|Vega:OTTHUMG00000182967 +55096 EBLN2 MIM:613250|HGNC:HGNC:25493|Ensembl:ENSG00000255423|Vega:OTTHUMG00000165897 +55100 WDR70 MIM:617233|HGNC:HGNC:25495|Ensembl:ENSG00000082068|Vega:OTTHUMG00000162263 +55101 DMAC2 MIM:617262|HGNC:HGNC:25496|Ensembl:ENSG00000105341|Vega:OTTHUMG00000182342 +55102 ATG2B MIM:616226|HGNC:HGNC:20187|Ensembl:ENSG00000066739|Vega:OTTHUMG00000149933 +55103 RALGPS2 HGNC:HGNC:30279|Ensembl:ENSG00000116191|Vega:OTTHUMG00000035076 +55105 GPATCH2 MIM:616836|HGNC:HGNC:25499|Ensembl:ENSG00000092978|Vega:OTTHUMG00000000527 +55106 SLFN12 MIM:614955|HGNC:HGNC:25500|Ensembl:ENSG00000172123|Vega:OTTHUMG00000132952 +55107 ANO1 MIM:610108|HGNC:HGNC:21625|Ensembl:ENSG00000131620|Vega:OTTHUMG00000167204 +55108 BSDC1 MIM:617518|HGNC:HGNC:25501|Ensembl:ENSG00000160058|Vega:OTTHUMG00000007588 +55109 AGGF1 MIM:608464|HGNC:HGNC:24684|Ensembl:ENSG00000164252|Vega:OTTHUMG00000102132 +55110 MAGOHB HGNC:HGNC:25504|Ensembl:ENSG00000111196|Vega:OTTHUMG00000168407 +55111 PLEKHJ1 HGNC:HGNC:18211|Ensembl:ENSG00000104886|Vega:OTTHUMG00000180425 +55112 WDR60 MIM:615462|HGNC:HGNC:21862|Ensembl:ENSG00000126870|Vega:OTTHUMG00000151443 +55113 XKR8 HGNC:HGNC:25508|Ensembl:ENSG00000158156|Vega:OTTHUMG00000003912 +55114 ARHGAP17 MIM:608293|HGNC:HGNC:18239|Ensembl:ENSG00000140750|Vega:OTTHUMG00000177372 +55116 TMEM39B HGNC:HGNC:25510|Ensembl:ENSG00000121775|Vega:OTTHUMG00000004020 +55117 SLC6A15 MIM:607971|HGNC:HGNC:13621|Ensembl:ENSG00000072041|Vega:OTTHUMG00000169742 +55118 CRTAC1 MIM:606276|HGNC:HGNC:14882|Ensembl:ENSG00000095713|Vega:OTTHUMG00000018871 +55119 PRPF38B HGNC:HGNC:25512|Ensembl:ENSG00000134186|Vega:OTTHUMG00000010991 +55120 FANCL MIM:608111|HGNC:HGNC:20748|Ensembl:ENSG00000115392|Vega:OTTHUMG00000129349 +55122 AKIRIN2 MIM:615165|HGNC:HGNC:21407|Ensembl:ENSG00000135334|Vega:OTTHUMG00000015180 +55124 PIWIL2 MIM:610312|HGNC:HGNC:17644|Ensembl:ENSG00000197181|Vega:OTTHUMG00000097767 +55125 CEP192 MIM:616426|HGNC:HGNC:25515|Ensembl:ENSG00000101639|Vega:OTTHUMG00000160693 +55127 HEATR1 HGNC:HGNC:25517|Ensembl:ENSG00000119285|Vega:OTTHUMG00000040061 +55128 TRIM68 MIM:613184|HGNC:HGNC:21161|Ensembl:ENSG00000167333|Vega:OTTHUMG00000165723 +55129 ANO10 MIM:613726|HGNC:HGNC:25519|Ensembl:ENSG00000160746|Vega:OTTHUMG00000133044 +55130 ARMC4 MIM:615408|HGNC:HGNC:25583|Ensembl:ENSG00000169126|Vega:OTTHUMG00000017867 +55131 RBM28 MIM:612074|HGNC:HGNC:21863|Ensembl:ENSG00000106344|Vega:OTTHUMG00000157711 +55132 LARP1B HGNC:HGNC:24704|Ensembl:ENSG00000138709|Vega:OTTHUMG00000133343 +55133 SRBD1 HGNC:HGNC:25521|Ensembl:ENSG00000068784|Vega:OTTHUMG00000128814 +55135 WRAP53 MIM:612661|HGNC:HGNC:25522|Ensembl:ENSG00000141499|Vega:OTTHUMG00000134323 +55137 FIGN MIM:605295|HGNC:HGNC:13285|Ensembl:ENSG00000182263|Vega:OTTHUMG00000074059 +55138 FAM90A1 MIM:613041|HGNC:HGNC:25526|Ensembl:ENSG00000171847|Vega:OTTHUMG00000168641 +55139 ANKZF1 MIM:617541|HGNC:HGNC:25527|Ensembl:ENSG00000163516|Vega:OTTHUMG00000154533 +55140 ELP3 MIM:612722|HGNC:HGNC:20696|Ensembl:ENSG00000134014|Vega:OTTHUMG00000102124 +55142 HAUS2 MIM:613429|HGNC:HGNC:25530|Ensembl:ENSG00000137814|Vega:OTTHUMG00000130678 +55143 CDCA8 MIM:609977|HGNC:HGNC:14629|Ensembl:ENSG00000134690|Vega:OTTHUMG00000004320 +55144 LRRC8D MIM:612890|HGNC:HGNC:16992|Ensembl:ENSG00000171492|Vega:OTTHUMG00000010583 +55145 THAP1 MIM:609520|HGNC:HGNC:20856|Ensembl:ENSG00000131931|Vega:OTTHUMG00000165276 +55146 ZDHHC4 HGNC:HGNC:18471|Ensembl:ENSG00000136247|Vega:OTTHUMG00000023579 +55147 RBM23 HGNC:HGNC:20155|Ensembl:ENSG00000100461|Vega:OTTHUMG00000171467 +55148 UBR7 MIM:613816|HGNC:HGNC:20344|Ensembl:ENSG00000012963|Vega:OTTHUMG00000171268 +55149 MTPAP MIM:613669|HGNC:HGNC:25532|Ensembl:ENSG00000107951|Vega:OTTHUMG00000017895 +55150 C19orf73 HGNC:HGNC:25534|Ensembl:ENSG00000221916|Vega:OTTHUMG00000183345 +55151 TMEM38B MIM:611236|HGNC:HGNC:25535|Ensembl:ENSG00000095209|Vega:OTTHUMG00000020429 +55152 DALRD3 HGNC:HGNC:25536|Ensembl:ENSG00000178149|Vega:OTTHUMG00000156748 +55153 SDAD1 HGNC:HGNC:25537|Ensembl:ENSG00000198301|Vega:OTTHUMG00000130111 +55154 MSTO1 HGNC:HGNC:29678|Ensembl:ENSG00000125459|Vega:OTTHUMG00000014014 +55156 ARMC1 HGNC:HGNC:17684|Ensembl:ENSG00000104442|Vega:OTTHUMG00000164374 +55157 DARS2 MIM:610956|HGNC:HGNC:25538|Ensembl:ENSG00000117593|Vega:OTTHUMG00000034803 +55159 RFWD3 MIM:614151|HGNC:HGNC:25539|Ensembl:ENSG00000168411|Vega:OTTHUMG00000177368 +55160 ARHGEF10L MIM:612494|HGNC:HGNC:25540|Ensembl:ENSG00000074964|Vega:OTTHUMG00000002514 +55161 TMEM33 HGNC:HGNC:25541|Ensembl:ENSG00000109133|Vega:OTTHUMG00000099381 +55163 PNPO MIM:603287|HGNC:HGNC:30260|Ensembl:ENSG00000108439|Vega:OTTHUMG00000178295 +55164 SHQ1 MIM:613663|HGNC:HGNC:25543|Ensembl:ENSG00000144736|Vega:OTTHUMG00000158814 +55165 CEP55 MIM:610000|HGNC:HGNC:1161|Ensembl:ENSG00000138180|Vega:OTTHUMG00000018774 +55166 CENPQ MIM:611506|HGNC:HGNC:21347|Ensembl:ENSG00000031691|Vega:OTTHUMG00000014815 +55167 MSL2 MIM:614802|HGNC:HGNC:25544|Ensembl:ENSG00000174579|Vega:OTTHUMG00000159793 +55168 MRPS18A MIM:611981|HGNC:HGNC:14515|Ensembl:ENSG00000096080|Vega:OTTHUMG00000014750 +55170 PRMT6 MIM:608274|HGNC:HGNC:18241|Ensembl:ENSG00000198890|Vega:OTTHUMG00000010964 +55171 TBCCD1 HGNC:HGNC:25546|Ensembl:ENSG00000113838|Vega:OTTHUMG00000156613 +55172 DNAAF2 MIM:612517|HGNC:HGNC:20188|Ensembl:ENSG00000165506|Vega:OTTHUMG00000152331 +55173 MRPS10 MIM:611976|HGNC:HGNC:14502|Ensembl:ENSG00000048544|Vega:OTTHUMG00000014694 +55174 INTS10 MIM:611353|HGNC:HGNC:25548|Ensembl:ENSG00000104613|Vega:OTTHUMG00000131065 +55175 KLHL11 HGNC:HGNC:19008|Ensembl:ENSG00000178502|Vega:OTTHUMG00000133506 +55176 SEC61A2 HGNC:HGNC:17702|Ensembl:ENSG00000065665|Vega:OTTHUMG00000017679 +55177 RMDN3 MIM:611873|HGNC:HGNC:25550|Ensembl:ENSG00000137824|Vega:OTTHUMG00000130066 +55178 MRM3 MIM:612600|HGNC:HGNC:18485|Ensembl:ENSG00000171861|Vega:OTTHUMG00000090285 +55179 FAIM MIM:617535|HGNC:HGNC:18703|Ensembl:ENSG00000158234|Vega:OTTHUMG00000159885 +55180 LINS1 MIM:610350|HGNC:HGNC:30922|Ensembl:ENSG00000140471|Vega:OTTHUMG00000149865 +55181 SMG8 MIM:613175|HGNC:HGNC:25551|Ensembl:ENSG00000167447|Vega:OTTHUMG00000179365 +55182 RNF220 MIM:616136|HGNC:HGNC:25552|Ensembl:ENSG00000187147|Vega:OTTHUMG00000007697 +55183 RIF1 MIM:608952|HGNC:HGNC:23207|Ensembl:ENSG00000080345|Vega:OTTHUMG00000131886 +55184 DZANK1 HGNC:HGNC:15858|Ensembl:ENSG00000089091|Vega:OTTHUMG00000031968 +55186 SLC25A36 MIM:616149|HGNC:HGNC:25554|Ensembl:ENSG00000114120|Vega:OTTHUMG00000160260 +55187 VPS13D MIM:608877|HGNC:HGNC:23595|Ensembl:ENSG00000048707|Vega:OTTHUMG00000013155 +55188 RIC8B MIM:609147|HGNC:HGNC:25555|Ensembl:ENSG00000111785|Vega:OTTHUMG00000144188 +55190 NUDT11 MIM:300528|HGNC:HGNC:18011|Ensembl:ENSG00000196368|Vega:OTTHUMG00000021531 +55191 NADSYN1 MIM:608285|HGNC:HGNC:29832|Ensembl:ENSG00000172890|Vega:OTTHUMG00000167375 +55192 DNAJC17 MIM:616844|HGNC:HGNC:25556|Ensembl:ENSG00000104129|Vega:OTTHUMG00000130065 +55193 PBRM1 MIM:606083|HGNC:HGNC:30064|Ensembl:ENSG00000163939|Vega:OTTHUMG00000152663 +55194 EVA1B HGNC:HGNC:25558|Ensembl:ENSG00000142694|Vega:OTTHUMG00000007867 +55195 CCDC198 HGNC:HGNC:20189|Ensembl:ENSG00000100557|Vega:OTTHUMG00000140317 +55196 KIAA1551 HGNC:HGNC:25559|Ensembl:ENSG00000174718|Vega:OTTHUMG00000128501 +55197 RPRD1A MIM:610347|HGNC:HGNC:25560|Ensembl:ENSG00000141425|Vega:OTTHUMG00000132591 +55198 APPL2 MIM:606231|HGNC:HGNC:18242|Ensembl:ENSG00000136044|Vega:OTTHUMG00000169853 +55199 FAM86C1 MIM:616124|HGNC:HGNC:25561|Ensembl:ENSG00000158483|Vega:OTTHUMG00000160552 +55200 PLEKHG6 MIM:611743|HGNC:HGNC:25562|Ensembl:ENSG00000008323|Vega:OTTHUMG00000168266 +55201 MAP1S MIM:607573|HGNC:HGNC:15715|Ensembl:ENSG00000130479|Vega:OTTHUMG00000183292 +55203 LGI2 MIM:608301|HGNC:HGNC:18710|Ensembl:ENSG00000153012|Vega:OTTHUMG00000097749 +55204 GOLPH3L MIM:612208|HGNC:HGNC:24882|Ensembl:ENSG00000143457|Vega:OTTHUMG00000035009 +55205 ZNF532 HGNC:HGNC:30940|Ensembl:ENSG00000074657|Vega:OTTHUMG00000132759 +55206 SBNO1 MIM:614274|HGNC:HGNC:22973|Ensembl:ENSG00000139697|Vega:OTTHUMG00000183988 +55207 ARL8B MIM:616596|HGNC:HGNC:25564|Ensembl:ENSG00000134108|Vega:OTTHUMG00000090463 +55208 DCUN1D2 HGNC:HGNC:20328|Ensembl:ENSG00000150401|Vega:OTTHUMG00000017390 +55209 SETD5 MIM:615743|HGNC:HGNC:25566|Ensembl:ENSG00000168137|Vega:OTTHUMG00000150491 +55210 ATAD3A MIM:612316|HGNC:HGNC:25567|Ensembl:ENSG00000197785|Vega:OTTHUMG00000000575 +55211 DPPA4 MIM:614125|HGNC:HGNC:19200|Ensembl:ENSG00000121570|Vega:OTTHUMG00000159222 +55212 BBS7 MIM:607590|HGNC:HGNC:18758|Ensembl:ENSG00000138686|Vega:OTTHUMG00000133076 +55213 RCBTB1 MIM:607867|HGNC:HGNC:18243|Ensembl:ENSG00000136144|Vega:OTTHUMG00000016915 +55214 P3H2 MIM:610341|HGNC:HGNC:19317|Ensembl:ENSG00000090530|Vega:OTTHUMG00000156312 +55215 FANCI MIM:611360|HGNC:HGNC:25568|Ensembl:ENSG00000140525|Vega:OTTHUMG00000132993 +55216 C11orf57 HGNC:HGNC:25569|Ensembl:ENSG00000150776|Vega:OTTHUMG00000150213 +55217 TMLHE MIM:300777|HGNC:HGNC:18308|Ensembl:ENSG00000185973|Vega:OTTHUMG00000022674 +55218 EXD2 MIM:616940|HGNC:HGNC:20217|Ensembl:ENSG00000081177|Vega:OTTHUMG00000154496 +55219 TMEM57 MIM:610301|HGNC:HGNC:25572|Ensembl:ENSG00000204178|Vega:OTTHUMG00000003473 +55220 KLHDC8A MIM:614503|HGNC:HGNC:25573|Ensembl:ENSG00000162873|Vega:OTTHUMG00000037199 +55222 LRRC20 HGNC:HGNC:23421|Ensembl:ENSG00000172731|Vega:OTTHUMG00000018407 +55223 TRIM62 MIM:616755|HGNC:HGNC:25574|Ensembl:ENSG00000116525|Vega:OTTHUMG00000004132 +55224 ETNK2 MIM:609859|HGNC:HGNC:25575|Ensembl:ENSG00000143845|Vega:OTTHUMG00000036061 +55225 RAVER2 MIM:609953|HGNC:HGNC:25577|Ensembl:ENSG00000162437|Vega:OTTHUMG00000009102 +55226 NAT10 MIM:609221|HGNC:HGNC:29830|Ensembl:ENSG00000135372|Vega:OTTHUMG00000166249 +55227 LRRC1 MIM:608195|HGNC:HGNC:14307|Ensembl:ENSG00000137269|Vega:OTTHUMG00000014885 +55228 PNMA8A HGNC:HGNC:25578|Ensembl:ENSG00000182013|Vega:OTTHUMG00000169421 +55229 PANK4 MIM:606162|HGNC:HGNC:19366|Ensembl:ENSG00000157881|Vega:OTTHUMG00000000791 +55230 USP40 MIM:610570|HGNC:HGNC:20069|Ensembl:ENSG00000085982|Vega:OTTHUMG00000153199 +55231 CCDC87 HGNC:HGNC:25579|Ensembl:ENSG00000182791|Vega:OTTHUMG00000167237 +55233 MOB1A MIM:609281|HGNC:HGNC:16015|Ensembl:ENSG00000114978|Vega:OTTHUMG00000152833 +55234 SMU1 HGNC:HGNC:18247|Ensembl:ENSG00000122692|Vega:OTTHUMG00000019757 +55236 UBA6 MIM:611361|HGNC:HGNC:25581|Ensembl:ENSG00000033178|Vega:OTTHUMG00000129299 +55237 VRTN HGNC:HGNC:20223|Ensembl:ENSG00000133980|Vega:OTTHUMG00000171208 +55238 SLC38A7 MIM:614236|HGNC:HGNC:25582|Ensembl:ENSG00000103042|Vega:OTTHUMG00000133491 +55239 OGFOD1 MIM:615857|HGNC:HGNC:25585|Ensembl:ENSG00000087263|Vega:OTTHUMG00000133237 +55240 STEAP3 MIM:609671|HGNC:HGNC:24592|Ensembl:ENSG00000115107|Vega:OTTHUMG00000131402 +55243 KIRREL1 MIM:607428|HGNC:HGNC:15734|Ensembl:ENSG00000183853|Vega:OTTHUMG00000022438 +55244 SLC47A1 MIM:609832|HGNC:HGNC:25588|Ensembl:ENSG00000142494|Vega:OTTHUMG00000059466 +55245 UQCC1 MIM:611797|HGNC:HGNC:15891|Ensembl:ENSG00000101019|Vega:OTTHUMG00000032335 +55246 CCDC25 HGNC:HGNC:25591|Ensembl:ENSG00000147419|Vega:OTTHUMG00000132173 +55247 NEIL3 MIM:608934|HGNC:HGNC:24573|Ensembl:ENSG00000109674|Vega:OTTHUMG00000160722 +55248 TMEM206 HGNC:HGNC:25593|Ensembl:ENSG00000065600|Vega:OTTHUMG00000036751 +55249 YY1AP1 MIM:607860|HGNC:HGNC:30935|Ensembl:ENSG00000163374|Vega:OTTHUMG00000035437 +55250 ELP2 MIM:616054|HGNC:HGNC:18248|Ensembl:ENSG00000134759|Vega:OTTHUMG00000132589 +55251 PCMTD2 HGNC:HGNC:15882|Ensembl:ENSG00000203880|Vega:OTTHUMG00000033029 +55252 ASXL2 MIM:612991|HGNC:HGNC:23805|Ensembl:ENSG00000143970|Vega:OTTHUMG00000152176 +55253 TYW1 MIM:611243|HGNC:HGNC:25598|Ensembl:ENSG00000198874|Vega:OTTHUMG00000129723 +55254 TMEM39A HGNC:HGNC:25600|Ensembl:ENSG00000176142|Vega:OTTHUMG00000159361 +55255 WDR41 MIM:617502|HGNC:HGNC:25601|Ensembl:ENSG00000164253|Vega:OTTHUMG00000102169 +55256 ADI1 MIM:613400|HGNC:HGNC:30576|Ensembl:ENSG00000182551|Vega:OTTHUMG00000112441 +55257 MRGBP MIM:611157|HGNC:HGNC:15866|Ensembl:ENSG00000101189|Vega:OTTHUMG00000032940 +55258 THNSL2 MIM:611261|HGNC:HGNC:25602|Ensembl:ENSG00000144115|Vega:OTTHUMG00000130314 +55259 CASC1 MIM:616906|HGNC:HGNC:29599|Ensembl:ENSG00000118307|Vega:OTTHUMG00000150195 +55260 TMEM143 HGNC:HGNC:25603|Ensembl:ENSG00000161558|Vega:OTTHUMG00000183197 +55262 C7orf43 HGNC:HGNC:25604|Ensembl:ENSG00000146826|Vega:OTTHUMG00000154862 +55266 TMEM19 HGNC:HGNC:25605|Ensembl:ENSG00000139291|Vega:OTTHUMG00000169558 +55267 PRR34 HGNC:HGNC:25606|Ensembl:ENSG00000182257|Vega:OTTHUMG00000150407 +55268 ECHDC2 HGNC:HGNC:23408|Ensembl:ENSG00000121310|Vega:OTTHUMG00000008927 +55269 PSPC1 MIM:612408|HGNC:HGNC:20320|Ensembl:ENSG00000121390|Vega:OTTHUMG00000016502 +55270 NUDT15 MIM:615792|HGNC:HGNC:23063|Ensembl:ENSG00000136159|Vega:OTTHUMG00000016890 +55272 IMP3 MIM:612980|HGNC:HGNC:14497|Ensembl:ENSG00000177971|Vega:OTTHUMG00000142840 +55273 TMEM100 MIM:616334|HGNC:HGNC:25607|Ensembl:ENSG00000166292|Vega:OTTHUMG00000177858 +55274 PHF10 MIM:613069|HGNC:HGNC:18250|Ensembl:ENSG00000130024|Vega:OTTHUMG00000016058 +55275 VPS53 MIM:615850|HGNC:HGNC:25608|Ensembl:ENSG00000141252|Vega:OTTHUMG00000177441 +55276 PGM2 MIM:172000|HGNC:HGNC:8906|Ensembl:ENSG00000169299|Vega:OTTHUMG00000097813 +55277 FGGY MIM:611370|HGNC:HGNC:25610|Ensembl:ENSG00000172456|Vega:OTTHUMG00000008424 +55278 QRSL1 MIM:617209|HGNC:HGNC:21020|Ensembl:ENSG00000130348|Vega:OTTHUMG00000015301 +55279 ZNF654 HGNC:HGNC:25612|Ensembl:ENSG00000175105|Vega:OTTHUMG00000159097 +55280 CWF19L1 MIM:616120|HGNC:HGNC:25613|Ensembl:ENSG00000095485|Vega:OTTHUMG00000018901 +55281 TMEM140 HGNC:HGNC:21870|Ensembl:ENSG00000146859|Vega:OTTHUMG00000155413 +55282 LRRC36 HGNC:HGNC:25615|Ensembl:ENSG00000159708|Vega:OTTHUMG00000173030 +55283 MCOLN3 MIM:607400|HGNC:HGNC:13358|Ensembl:ENSG00000055732|Vega:OTTHUMG00000009955 +55284 UBE2W MIM:614277|HGNC:HGNC:25616|Ensembl:ENSG00000104343|Vega:OTTHUMG00000164517 +55285 RBM41 HGNC:HGNC:25617|Ensembl:ENSG00000089682|Vega:OTTHUMG00000022156 +55286 C4orf19 HGNC:HGNC:25618|Ensembl:ENSG00000154274|Vega:OTTHUMG00000128580 +55287 TMEM40 HGNC:HGNC:25620|Ensembl:ENSG00000088726|Vega:OTTHUMG00000129801 +55288 RHOT1 MIM:613888|HGNC:HGNC:21168|Ensembl:ENSG00000126858|Vega:OTTHUMG00000179564 +55289 ACOXL HGNC:HGNC:25621|Ensembl:ENSG00000153093|Vega:OTTHUMG00000131257 +55290 BRF2 MIM:607013|HGNC:HGNC:17298|Ensembl:ENSG00000104221|Vega:OTTHUMG00000164025 +55291 PPP6R3 MIM:610879|HGNC:HGNC:1173|Ensembl:ENSG00000110075|Vega:OTTHUMG00000167596 +55293 UEVLD MIM:610985|HGNC:HGNC:30866|Ensembl:ENSG00000151116|Vega:OTTHUMG00000167729 +55294 FBXW7 MIM:606278|HGNC:HGNC:16712|Ensembl:ENSG00000109670|Vega:OTTHUMG00000185246 +55295 KLHL26 HGNC:HGNC:25623|Ensembl:ENSG00000167487|Vega:OTTHUMG00000183114 +55296 TBC1D19 HGNC:HGNC:25624|Ensembl:ENSG00000109680|Vega:OTTHUMG00000097797 +55297 CCDC91 MIM:617366|HGNC:HGNC:24855|Ensembl:ENSG00000123106|Vega:OTTHUMG00000169141 +55298 RNF121 HGNC:HGNC:21070|Ensembl:ENSG00000137522|Vega:OTTHUMG00000157023 +55299 BRIX1 HGNC:HGNC:24170|Ensembl:ENSG00000113460|Vega:OTTHUMG00000162021 +55300 PI4K2B MIM:612101|HGNC:HGNC:18215|Ensembl:ENSG00000038210|Ensembl:ENSG00000281028|Vega:OTTHUMG00000128564|Vega:OTTHUMG00000189521 +55301 OLAH HGNC:HGNC:25625|Ensembl:ENSG00000152463|Vega:OTTHUMG00000017724 +55303 GIMAP4 MIM:608087|HGNC:HGNC:21872|Ensembl:ENSG00000133574|Vega:OTTHUMG00000157475 +55304 SPTLC3 MIM:611120|HGNC:HGNC:16253|Ensembl:ENSG00000172296|Vega:OTTHUMG00000031899 +55308 DDX19A HGNC:HGNC:25628|Ensembl:ENSG00000168872|Ensembl:ENSG00000260537|Vega:OTTHUMG00000137579|Vega:OTTHUMG00000177063 +55311 ZNF444 MIM:607874|HGNC:HGNC:16052|Ensembl:ENSG00000167685|Vega:OTTHUMG00000181761 +55312 RFK MIM:613010|HGNC:HGNC:30324|Ensembl:ENSG00000135002|Vega:OTTHUMG00000020040 +55313 CPPED1 MIM:615603|HGNC:HGNC:25632|Ensembl:ENSG00000103381|Vega:OTTHUMG00000167711 +55314 TMEM144 HGNC:HGNC:25633|Ensembl:ENSG00000164124|Vega:OTTHUMG00000162013 +55315 SLC29A3 MIM:612373|HGNC:HGNC:23096|Ensembl:ENSG00000198246|Vega:OTTHUMG00000018424 +55316 RSAD1 HGNC:HGNC:25634|Ensembl:ENSG00000136444|Vega:OTTHUMG00000162126 +55317 AP5S1 MIM:614824|HGNC:HGNC:15875|Ensembl:ENSG00000125843|Vega:OTTHUMG00000031760 +55319 TMA16 HGNC:HGNC:25638|Ensembl:ENSG00000198498|Vega:OTTHUMG00000161528 +55320 MIS18BP1 HGNC:HGNC:20190|Ensembl:ENSG00000129534|Vega:OTTHUMG00000140266 +55321 TMEM74B HGNC:HGNC:15893|Ensembl:ENSG00000125895|Vega:OTTHUMG00000031655 +55322 C5orf22 HGNC:HGNC:25639|Ensembl:ENSG00000082213|Vega:OTTHUMG00000131067 +55323 LARP6 MIM:611300|HGNC:HGNC:24012|Ensembl:ENSG00000166173|Vega:OTTHUMG00000172179 +55324 ABCF3 HGNC:HGNC:72|Ensembl:ENSG00000161204|Vega:OTTHUMG00000156824 +55325 UFSP2 MIM:611482|HGNC:HGNC:25640|Ensembl:ENSG00000109775|Vega:OTTHUMG00000160441 +55326 AGPAT5 MIM:614796|HGNC:HGNC:20886|Ensembl:ENSG00000155189|Vega:OTTHUMG00000163656 +55327 LIN7C MIM:612332|HGNC:HGNC:17789|Ensembl:ENSG00000148943|Vega:OTTHUMG00000166193 +55328 RNLS MIM:609360|HGNC:HGNC:25641|Ensembl:ENSG00000184719|Vega:OTTHUMG00000018692 +55329 MNS1 MIM:610766|HGNC:HGNC:29636|Ensembl:ENSG00000138587|Vega:OTTHUMG00000132034 +55330 BLOC1S4 MIM:605695|HGNC:HGNC:24206|Ensembl:ENSG00000186222|Vega:OTTHUMG00000125510 +55331 ACER3 MIM:617036|HGNC:HGNC:16066|Ensembl:ENSG00000078124|Vega:OTTHUMG00000165225 +55332 DRAM1 MIM:610776|HGNC:HGNC:25645|Ensembl:ENSG00000136048|Vega:OTTHUMG00000170447 +55333 SYNJ2BP MIM:609411|HGNC:HGNC:18955|Ensembl:ENSG00000213463|Vega:OTTHUMG00000171240 +55334 SLC39A9 HGNC:HGNC:20182|Ensembl:ENSG00000029364|Vega:OTTHUMG00000171232 +55335 NIPSNAP3B MIM:608872|HGNC:HGNC:23641|Ensembl:ENSG00000165028|Vega:OTTHUMG00000020414 +55336 FBXL8 MIM:609077|HGNC:HGNC:17875|Ensembl:ENSG00000135722|Vega:OTTHUMG00000137514 +55337 C19orf66 MIM:616808|HGNC:HGNC:25649|Ensembl:ENSG00000130813|Vega:OTTHUMG00000180393 +55338 LINC01949 HGNC:HGNC:25650 +55339 WDR33 HGNC:HGNC:25651|Ensembl:ENSG00000136709|Vega:OTTHUMG00000131534 +55340 GIMAP5 MIM:608086|HGNC:HGNC:18005|Ensembl:ENSG00000196329|Vega:OTTHUMG00000157542 +55341 LSG1 MIM:610780|HGNC:HGNC:25652|Ensembl:ENSG00000041802|Vega:OTTHUMG00000156021 +55342 STRBP MIM:611138|HGNC:HGNC:16462|Ensembl:ENSG00000165209|Vega:OTTHUMG00000020636 +55343 SLC35C1 MIM:605881|HGNC:HGNC:20197|Ensembl:ENSG00000181830|Vega:OTTHUMG00000166519 +55344 PLCXD1 MIM:300974|HGNC:HGNC:23148|Ensembl:ENSG00000182378|Vega:OTTHUMG00000022693 +55345 ZGRF1 HGNC:HGNC:25654|Ensembl:ENSG00000138658|Vega:OTTHUMG00000132908 +55346 TCP11L1 HGNC:HGNC:25655|Ensembl:ENSG00000176148|Vega:OTTHUMG00000165303 +55347 ABHD10 HGNC:HGNC:25656|Ensembl:ENSG00000144827|Vega:OTTHUMG00000159280 +55349 CHDH HGNC:HGNC:24288|Ensembl:ENSG00000016391|Vega:OTTHUMG00000158281 +55350 VNN3 MIM:606592|HGNC:HGNC:16431 +55351 STK32B HGNC:HGNC:14217|Ensembl:ENSG00000152953|Vega:OTTHUMG00000090423 +55352 COPRS HGNC:HGNC:28848|Ensembl:ENSG00000172301|Vega:OTTHUMG00000132812 +55353 LAPTM4B MIM:613296|HGNC:HGNC:13646|Ensembl:ENSG00000104341|Vega:OTTHUMG00000164740 +55355 HJURP MIM:612667|HGNC:HGNC:25444|Ensembl:ENSG00000123485|Vega:OTTHUMG00000059125 +55356 SLC22A15 MIM:608275|HGNC:HGNC:20301|Ensembl:ENSG00000163393|Vega:OTTHUMG00000012008 +55357 TBC1D2 MIM:609871|HGNC:HGNC:18026|Ensembl:ENSG00000095383|Vega:OTTHUMG00000020343 +55359 STYK1 MIM:611433|HGNC:HGNC:18889|Ensembl:ENSG00000060140|Vega:OTTHUMG00000168408 +55361 PI4K2A MIM:609763|HGNC:HGNC:30031|Ensembl:ENSG00000155252|Vega:OTTHUMG00000018863 +55362 TMEM63B HGNC:HGNC:17735|Ensembl:ENSG00000137216|Vega:OTTHUMG00000014757 +55363 HEMGN MIM:610715|HGNC:HGNC:17509|Ensembl:ENSG00000136929|Vega:OTTHUMG00000020336 +55364 IMPACT MIM:615319|HGNC:HGNC:20387|Ensembl:ENSG00000154059|Vega:OTTHUMG00000131943 +55365 TMEM176A MIM:610334|HGNC:HGNC:24930|Ensembl:ENSG00000002933|Vega:OTTHUMG00000158114 +55366 LGR4 MIM:606666|HGNC:HGNC:13299|Ensembl:ENSG00000205213|Vega:OTTHUMG00000133508 +55367 PIDD1 MIM:605247|HGNC:HGNC:16491|Ensembl:ENSG00000177595|Vega:OTTHUMG00000133306 +55370 PPP4R1L HGNC:HGNC:15755 +55374 TMCO6 HGNC:HGNC:28814|Ensembl:ENSG00000113119|Vega:OTTHUMG00000129497 +55379 LRRC59 MIM:614854|HGNC:HGNC:28817|Ensembl:ENSG00000108829|Vega:OTTHUMG00000162079 +55380 EPS15P1 HGNC:HGNC:18166 +55384 MEG3 MIM:605636|HGNC:HGNC:14575|Ensembl:ENSG00000214548 +55388 MCM10 MIM:609357|HGNC:HGNC:18043|Ensembl:ENSG00000065328|Vega:OTTHUMG00000017694 +55390 PRO2268 MIM:614354 +55421 NCBP3 MIM:616624|HGNC:HGNC:24612|Ensembl:ENSG00000074356|Vega:OTTHUMG00000177672 +55422 ZNF331 MIM:606043|HGNC:HGNC:15489|Ensembl:ENSG00000130844|Vega:OTTHUMG00000163019 +55423 SIRPG MIM:605466|HGNC:HGNC:15757|Ensembl:ENSG00000089012|Vega:OTTHUMG00000031680 +55425 GPALPP1 HGNC:HGNC:20298|Ensembl:ENSG00000133114|Vega:OTTHUMG00000016841 +55432 YOD1 MIM:612023|HGNC:HGNC:25035|Ensembl:ENSG00000180667|Vega:OTTHUMG00000036032 +55435 AP1AR MIM:610851|HGNC:HGNC:28808|Ensembl:ENSG00000138660|Vega:OTTHUMG00000132849 +55437 STRADB MIM:607333|HGNC:HGNC:13205|Ensembl:ENSG00000082146|Vega:OTTHUMG00000132831 +55449 DHRS4-AS1 MIM:616925|HGNC:HGNC:23175|Ensembl:ENSG00000215256 +55450 CAMK2N1 MIM:614986|HGNC:HGNC:24190|Ensembl:ENSG00000162545|Vega:OTTHUMG00000002837 +55451 LINC00216 HGNC:HGNC:20191 +55454 CSGALNACT2 MIM:616616|HGNC:HGNC:24292|Ensembl:ENSG00000169826|Vega:OTTHUMG00000018023 +55466 DNAJA4 HGNC:HGNC:14885|Ensembl:ENSG00000140403|Vega:OTTHUMG00000143733 +55471 NDUFAF7 MIM:615898|HGNC:HGNC:28816|Ensembl:ENSG00000003509|Vega:OTTHUMG00000128468 +55472 RBM12B-AS1 HGNC:HGNC:28818|Ensembl:ENSG00000279331 +55486 PARL MIM:607858|HGNC:HGNC:18253|Ensembl:ENSG00000175193|Vega:OTTHUMG00000156890 +55500 ETNK1 MIM:609858|HGNC:HGNC:24649|Ensembl:ENSG00000139163|Vega:OTTHUMG00000169008 +55501 CHST12 MIM:610129|HGNC:HGNC:17423|Ensembl:ENSG00000136213|Vega:OTTHUMG00000023849 +55502 HES6 MIM:610331|HGNC:HGNC:18254|Ensembl:ENSG00000144485|Vega:OTTHUMG00000133340 +55503 TRPV6 MIM:606680|HGNC:HGNC:14006|Ensembl:ENSG00000165125|Vega:OTTHUMG00000157158 +55504 TNFRSF19 MIM:606122|HGNC:HGNC:11915|Ensembl:ENSG00000127863|Vega:OTTHUMG00000016568 +55505 NOP10 MIM:606471|HGNC:HGNC:14378|Ensembl:ENSG00000182117|Vega:OTTHUMG00000129440 +55506 H2AFY2 MIM:616141|HGNC:HGNC:14453|Ensembl:ENSG00000099284|Vega:OTTHUMG00000018396 +55507 GPRC5D MIM:607437|HGNC:HGNC:13310|Ensembl:ENSG00000111291|Vega:OTTHUMG00000168711 +55508 SLC35E3 HGNC:HGNC:20864|Ensembl:ENSG00000175782|Vega:OTTHUMG00000169282 +55509 BATF3 MIM:612470|HGNC:HGNC:28915|Ensembl:ENSG00000123685|Vega:OTTHUMG00000036807 +55510 DDX43 MIM:606286|HGNC:HGNC:18677|Ensembl:ENSG00000080007|Vega:OTTHUMG00000015033 +55511 SAGE1 MIM:300359|HGNC:HGNC:30369|Ensembl:ENSG00000181433|Vega:OTTHUMG00000022496 +55512 SMPD3 MIM:605777|HGNC:HGNC:14240|Ensembl:ENSG00000103056|Vega:OTTHUMG00000137559 +55515 ASIC4 MIM:606715|HGNC:HGNC:21263|Ensembl:ENSG00000072182|Vega:OTTHUMG00000058928 +55520 ELAC1 MIM:608079|HGNC:HGNC:14197|Ensembl:ENSG00000141642|Vega:OTTHUMG00000132695 +55521 TRIM36 MIM:609317|HGNC:HGNC:16280|Ensembl:ENSG00000152503|Vega:OTTHUMG00000128892 +55526 DHTKD1 MIM:614984|HGNC:HGNC:23537|Ensembl:ENSG00000181192|Vega:OTTHUMG00000017677 +55527 FEM1A MIM:613538|HGNC:HGNC:16934|Ensembl:ENSG00000141965|Vega:OTTHUMG00000182048 +55529 TMEM55A MIM:609864|HGNC:HGNC:25452|Ensembl:ENSG00000155099|Vega:OTTHUMG00000164019 +55530 SVOP MIM:611699|HGNC:HGNC:25417|Ensembl:ENSG00000166111|Vega:OTTHUMG00000169432 +55531 ELMOD1 MIM:615456|HGNC:HGNC:25334|Ensembl:ENSG00000110675|Vega:OTTHUMG00000166361 +55532 SLC30A10 MIM:611146|HGNC:HGNC:25355|Ensembl:ENSG00000196660|Vega:OTTHUMG00000037434 +55534 MAML3 MIM:608991|HGNC:HGNC:16272|Ensembl:ENSG00000196782|Vega:OTTHUMG00000161441 +55536 CDCA7L MIM:609685|HGNC:HGNC:30777|Ensembl:ENSG00000164649|Vega:OTTHUMG00000128429 +55539 KCNQ1DN MIM:610980|HGNC:HGNC:13335|Ensembl:ENSG00000237941 +55540 IL17RB MIM:605458|HGNC:HGNC:18015|Ensembl:ENSG00000056736|Vega:OTTHUMG00000158280 +55544 RBM38 MIM:612428|HGNC:HGNC:15818|Ensembl:ENSG00000132819|Vega:OTTHUMG00000032820 +55545 MSX2P1 HGNC:HGNC:24976 +55552 ZNF823 HGNC:HGNC:30936|Ensembl:ENSG00000197933|Vega:OTTHUMG00000156528 +55553 SOX6 MIM:607257|HGNC:HGNC:16421|Ensembl:ENSG00000110693|Vega:OTTHUMG00000165876 +55554 KLK15 MIM:610601|HGNC:HGNC:20453|Ensembl:ENSG00000174562|Vega:OTTHUMG00000183116 +55556 ENOSF1 MIM:607427|HGNC:HGNC:30365|Ensembl:ENSG00000132199|Vega:OTTHUMG00000131470 +55558 PLXNA3 MIM:300022|HGNC:HGNC:9101|Ensembl:ENSG00000130827|Vega:OTTHUMG00000033290 +55559 HAUS7 MIM:300540|HGNC:HGNC:32979|Ensembl:ENSG00000213397|Vega:OTTHUMG00000159321 +55561 CDC42BPG MIM:613991|HGNC:HGNC:29829|Ensembl:ENSG00000171219|Vega:OTTHUMG00000045365 +55565 ZNF821 HGNC:HGNC:28043|Ensembl:ENSG00000102984|Vega:OTTHUMG00000176874 +55567 DNAH3 MIM:603334|HGNC:HGNC:2949|Ensembl:ENSG00000158486|Vega:OTTHUMG00000090677 +55568 GALNT10 MIM:608043|HGNC:HGNC:19873|Ensembl:ENSG00000164574|Vega:OTTHUMG00000130145 +55571 CNOT11 HGNC:HGNC:25217|Ensembl:ENSG00000158435|Vega:OTTHUMG00000130686 +55572 FOXRED1 MIM:613622|HGNC:HGNC:26927|Ensembl:ENSG00000110074|Vega:OTTHUMG00000165827 +55573 CDV3 HGNC:HGNC:26928|Ensembl:ENSG00000091527|Vega:OTTHUMG00000159764 +55576 STAB2 MIM:608561|HGNC:HGNC:18629|Ensembl:ENSG00000136011|Vega:OTTHUMG00000170056 +55577 NAGK MIM:606828|HGNC:HGNC:17174|Ensembl:ENSG00000124357|Vega:OTTHUMG00000153239 +55578 SUPT20H MIM:613417|HGNC:HGNC:20596|Ensembl:ENSG00000102710|Vega:OTTHUMG00000016747 +55582 KIF27 MIM:611253|HGNC:HGNC:18632|Ensembl:ENSG00000165115|Vega:OTTHUMG00000020109 +55584 CHRNA9 MIM:605116|HGNC:HGNC:14079|Ensembl:ENSG00000174343|Vega:OTTHUMG00000099375 +55585 UBE2Q1 MIM:617429|HGNC:HGNC:15698|Ensembl:ENSG00000160714|Vega:OTTHUMG00000037265 +55586 MIOX MIM:606774|HGNC:HGNC:14522|Ensembl:ENSG00000100253|Vega:OTTHUMG00000150207 +55588 MED29 MIM:612914|HGNC:HGNC:23074|Ensembl:ENSG00000063322|Vega:OTTHUMG00000182969 +55589 BMP2K HGNC:HGNC:18041|Ensembl:ENSG00000138756|Vega:OTTHUMG00000160900 +55591 VEZT HGNC:HGNC:18258|Ensembl:ENSG00000028203|Vega:OTTHUMG00000170182 +55592 GOLGA2P5 HGNC:HGNC:25315|Ensembl:ENSG00000238105 +55593 OTUD5 MIM:300713|HGNC:HGNC:25402|Ensembl:ENSG00000068308|Vega:OTTHUMG00000024130 +55596 ZCCHC8 MIM:616381|HGNC:HGNC:25265|Ensembl:ENSG00000033030|Vega:OTTHUMG00000168878 +55599 RNPC3 HGNC:HGNC:18666|Ensembl:ENSG00000185946|Vega:OTTHUMG00000166613 +55600 ITLN1 MIM:609873|HGNC:HGNC:18259|Ensembl:ENSG00000179914|Vega:OTTHUMG00000028604 +55601 DDX60 MIM:613974|HGNC:HGNC:25942|Ensembl:ENSG00000137628|Vega:OTTHUMG00000161350 +55602 CDKN2AIP MIM:615914|HGNC:HGNC:24325|Ensembl:ENSG00000168564|Vega:OTTHUMG00000160626 +55603 FAM46A MIM:611357|HGNC:HGNC:18345|Ensembl:ENSG00000112773|Vega:OTTHUMG00000015097 +55604 CARMIL1 MIM:609593|HGNC:HGNC:21581|Ensembl:ENSG00000079691|Vega:OTTHUMG00000014393 +55605 KIF21A MIM:608283|HGNC:HGNC:19349|Ensembl:ENSG00000139116|Vega:OTTHUMG00000169335 +55607 PPP1R9A MIM:602468|HGNC:HGNC:14946|Ensembl:ENSG00000158528|Vega:OTTHUMG00000155566 +55608 ANKRD10 HGNC:HGNC:20265|Ensembl:ENSG00000088448|Vega:OTTHUMG00000017349 +55609 ZNF280C HGNC:HGNC:25955|Ensembl:ENSG00000056277|Vega:OTTHUMG00000022393 +55610 VPS50 MIM:616465|HGNC:HGNC:25956|Ensembl:ENSG00000004766|Vega:OTTHUMG00000131733 +55611 OTUB1 MIM:608337|HGNC:HGNC:23077|Ensembl:ENSG00000167770|Vega:OTTHUMG00000167786 +55612 FERMT1 MIM:607900|HGNC:HGNC:15889|Ensembl:ENSG00000101311|Vega:OTTHUMG00000031826 +55613 MTMR8 HGNC:HGNC:16825|Ensembl:ENSG00000102043|Vega:OTTHUMG00000021707 +55614 KIF16B HGNC:HGNC:15869|Ensembl:ENSG00000089177|Vega:OTTHUMG00000031927 +55615 PRR5 MIM:609406|HGNC:HGNC:31682|Ensembl:ENSG00000186654|Vega:OTTHUMG00000150460 +55616 ASAP3 MIM:616594|HGNC:HGNC:14987|Ensembl:ENSG00000088280|Vega:OTTHUMG00000003234 +55617 TASP1 MIM:608270|HGNC:HGNC:15859|Ensembl:ENSG00000089123|Vega:OTTHUMG00000031904 +55619 DOCK10 MIM:611518|HGNC:HGNC:23479|Ensembl:ENSG00000135905|Vega:OTTHUMG00000153428 +55620 STAP2 MIM:607881|HGNC:HGNC:30430|Ensembl:ENSG00000178078|Vega:OTTHUMG00000181884 +55621 TRMT1 MIM:611669|HGNC:HGNC:25980|Ensembl:ENSG00000104907|Vega:OTTHUMG00000180730 +55622 TTC27 HGNC:HGNC:25986|Ensembl:ENSG00000018699|Vega:OTTHUMG00000152134 +55623 THUMPD1 MIM:616662|HGNC:HGNC:23807|Ensembl:ENSG00000066654|Vega:OTTHUMG00000131558 +55624 POMGNT1 MIM:606822|HGNC:HGNC:19139|Ensembl:ENSG00000085998|Vega:OTTHUMG00000007604 +55625 ZDHHC7 MIM:614604|HGNC:HGNC:18459|Ensembl:ENSG00000153786|Vega:OTTHUMG00000137645 +55626 AMBRA1 MIM:611359|HGNC:HGNC:25990|Ensembl:ENSG00000110497|Vega:OTTHUMG00000166500 +55627 SMPD4 MIM:610457|HGNC:HGNC:32949|Ensembl:ENSG00000136699|Vega:OTTHUMG00000131624 +55628 ZNF407 MIM:615894|HGNC:HGNC:19904|Ensembl:ENSG00000215421|Vega:OTTHUMG00000179122 +55629 PNRC2 MIM:611882|HGNC:HGNC:23158|Ensembl:ENSG00000189266|Vega:OTTHUMG00000013891 +55630 SLC39A4 MIM:607059|HGNC:HGNC:17129|Ensembl:ENSG00000147804|Vega:OTTHUMG00000165208 +55631 LRRC40 HGNC:HGNC:26004|Ensembl:ENSG00000066557|Vega:OTTHUMG00000009348 +55632 G2E3 MIM:611299|HGNC:HGNC:20338|Ensembl:ENSG00000092140|Vega:OTTHUMG00000140204 +55633 TBC1D22B MIM:616880|HGNC:HGNC:21602|Ensembl:ENSG00000065491|Vega:OTTHUMG00000014619 +55634 KRBOX4 MIM:300585|HGNC:HGNC:26007|Ensembl:ENSG00000147121|Vega:OTTHUMG00000021421 +55635 DEPDC1 MIM:612002|HGNC:HGNC:22949|Ensembl:ENSG00000024526|Vega:OTTHUMG00000009212 +55636 CHD7 MIM:608892|HGNC:HGNC:20626|Ensembl:ENSG00000171316|Vega:OTTHUMG00000165332 +55638 SYBU MIM:611568|HGNC:HGNC:26011|Ensembl:ENSG00000147642|Vega:OTTHUMG00000165634 +55640 FLVCR2 MIM:610865|HGNC:HGNC:20105|Ensembl:ENSG00000119686|Vega:OTTHUMG00000171487 +55643 BTBD2 MIM:608531|HGNC:HGNC:15504|Ensembl:ENSG00000133243|Vega:OTTHUMG00000180017 +55644 OSGEP MIM:610107|HGNC:HGNC:18028|Ensembl:ENSG00000092094|Vega:OTTHUMG00000029543 +55646 LYAR HGNC:HGNC:26021|Ensembl:ENSG00000145220|Vega:OTTHUMG00000125477 +55647 RAB20 HGNC:HGNC:18260|Ensembl:ENSG00000139832|Vega:OTTHUMG00000017343 +55650 PIGV MIM:610274|HGNC:HGNC:26031|Ensembl:ENSG00000060642|Vega:OTTHUMG00000004005 +55651 NHP2 MIM:606470|HGNC:HGNC:14377|Ensembl:ENSG00000145912|Vega:OTTHUMG00000130886 +55652 SLC48A1 MIM:612187|HGNC:HGNC:26035|Ensembl:ENSG00000211584|Vega:OTTHUMG00000156983 +55653 BCAS4 MIM:607471|HGNC:HGNC:14367|Ensembl:ENSG00000124243|Vega:OTTHUMG00000032735 +55654 TMEM127 MIM:613403|HGNC:HGNC:26038|Ensembl:ENSG00000135956|Vega:OTTHUMG00000130454 +55655 NLRP2 MIM:609364|HGNC:HGNC:22948|Ensembl:ENSG00000022556|Vega:OTTHUMG00000167763 +55656 INTS8 MIM:611351|HGNC:HGNC:26048|Ensembl:ENSG00000164941|Vega:OTTHUMG00000164695 +55657 ZNF692 HGNC:HGNC:26049|Ensembl:ENSG00000171163|Vega:OTTHUMG00000040423 +55658 RNF126 MIM:615177|HGNC:HGNC:21151|Ensembl:ENSG00000070423|Vega:OTTHUMG00000180592 +55659 ZNF416 HGNC:HGNC:20645|Ensembl:ENSG00000083817|Vega:OTTHUMG00000183467 +55660 PRPF40A MIM:612941|HGNC:HGNC:16463|Ensembl:ENSG00000196504|Vega:OTTHUMG00000154031 +55661 DDX27 MIM:616621|HGNC:HGNC:15837|Ensembl:ENSG00000124228|Vega:OTTHUMG00000033072 +55662 HIF1AN MIM:606615|HGNC:HGNC:17113|Ensembl:ENSG00000166135|Vega:OTTHUMG00000018911 +55663 ZNF446 HGNC:HGNC:21036|Ensembl:ENSG00000083838|Vega:OTTHUMG00000183541 +55664 CDC37L1 MIM:610346|HGNC:HGNC:17179|Ensembl:ENSG00000106993|Vega:OTTHUMG00000019465 +55665 URGCP MIM:610337|HGNC:HGNC:30890|Ensembl:ENSG00000106608|Vega:OTTHUMG00000155245 +55666 NPLOC4 MIM:606590|HGNC:HGNC:18261|Ensembl:ENSG00000182446|Vega:OTTHUMG00000177990 +55667 DENND4C HGNC:HGNC:26079|Ensembl:ENSG00000137145|Vega:OTTHUMG00000019627 +55668 GPATCH2L HGNC:HGNC:20210|Ensembl:ENSG00000089916|Vega:OTTHUMG00000171490 +55669 MFN1 MIM:608506|HGNC:HGNC:18262|Ensembl:ENSG00000171109|Vega:OTTHUMG00000157385 +55670 PEX26 MIM:608666|HGNC:HGNC:22965|Ensembl:ENSG00000215193|Vega:OTTHUMG00000149970 +55671 PPP4R3A MIM:610351|HGNC:HGNC:20219|Ensembl:ENSG00000100796|Vega:OTTHUMG00000171102 +55672 NBPF1 MIM:610501|HGNC:HGNC:26088|Ensembl:ENSG00000219481|Vega:OTTHUMG00000002487 +55676 SLC30A6 MIM:611148|HGNC:HGNC:19305|Ensembl:ENSG00000152683|Vega:OTTHUMG00000128456 +55677 IWS1 HGNC:HGNC:25467|Ensembl:ENSG00000163166|Vega:OTTHUMG00000131527 +55679 LIMS2 MIM:607908|HGNC:HGNC:16084|Ensembl:ENSG00000072163|Vega:OTTHUMG00000131529 +55680 RUFY2 MIM:610328|HGNC:HGNC:19761|Ensembl:ENSG00000204130|Vega:OTTHUMG00000018353 +55681 SCYL2 MIM:616365|HGNC:HGNC:19286|Ensembl:ENSG00000136021|Vega:OTTHUMG00000170319 +55683 KANSL3 HGNC:HGNC:25473|Ensembl:ENSG00000114982|Vega:OTTHUMG00000155249 +55684 RABL6 MIM:610615|HGNC:HGNC:24703|Ensembl:ENSG00000196642|Vega:OTTHUMG00000020947 +55686 MREG MIM:609207|HGNC:HGNC:25478|Ensembl:ENSG00000118242|Vega:OTTHUMG00000154828 +55687 TRMU MIM:610230|HGNC:HGNC:25481|Ensembl:ENSG00000100416|Vega:OTTHUMG00000150424 +55689 YEATS2 MIM:613373|HGNC:HGNC:25489|Ensembl:ENSG00000163872|Vega:OTTHUMG00000156898 +55690 PACS1 MIM:607492|HGNC:HGNC:30032|Ensembl:ENSG00000175115|Vega:OTTHUMG00000166889 +55691 FRMD4A MIM:616305|HGNC:HGNC:25491|Ensembl:ENSG00000151474|Vega:OTTHUMG00000017708 +55692 LUC7L MIM:607782|HGNC:HGNC:6723|Ensembl:ENSG00000007392|Vega:OTTHUMG00000060730 +55693 KDM4D MIM:609766|HGNC:HGNC:25498|Ensembl:ENSG00000186280|Vega:OTTHUMG00000167838 +55695 NSUN5 MIM:615732|HGNC:HGNC:16385|Ensembl:ENSG00000130305|Vega:OTTHUMG00000129869 +55696 RBM22 MIM:612430|HGNC:HGNC:25503|Ensembl:ENSG00000086589|Vega:OTTHUMG00000163589 +55697 VAC14 MIM:604632|HGNC:HGNC:25507|Ensembl:ENSG00000103043|Vega:OTTHUMG00000137583 +55698 RADIL MIM:611491|HGNC:HGNC:22226|Ensembl:ENSG00000157927|Vega:OTTHUMG00000151753 +55699 IARS2 MIM:612801|HGNC:HGNC:29685|Ensembl:ENSG00000067704|Vega:OTTHUMG00000037287 +55700 MAP7D1 HGNC:HGNC:25514|Ensembl:ENSG00000116871|Vega:OTTHUMG00000007714 +55701 ARHGEF40 MIM:610018|HGNC:HGNC:25516|Ensembl:ENSG00000165801|Vega:OTTHUMG00000171359 +55702 CCDC94 HGNC:HGNC:25518|Ensembl:ENSG00000105248|Vega:OTTHUMG00000181867 +55703 POLR3B MIM:614366|HGNC:HGNC:30348|Ensembl:ENSG00000013503|Vega:OTTHUMG00000170077 +55704 CCDC88A MIM:609736|HGNC:HGNC:25523|Ensembl:ENSG00000115355|Vega:OTTHUMG00000151915 +55705 IPO9 HGNC:HGNC:19425|Ensembl:ENSG00000198700|Vega:OTTHUMG00000035805 +55706 NDC1 MIM:610115|HGNC:HGNC:25525|Ensembl:ENSG00000058804|Vega:OTTHUMG00000008073 +55707 NECAP2 MIM:611624|HGNC:HGNC:25528|Ensembl:ENSG00000157191|Vega:OTTHUMG00000002313 +55709 KBTBD4 HGNC:HGNC:23761|Ensembl:ENSG00000123444|Vega:OTTHUMG00000166894 +55711 FAR2 MIM:616156|HGNC:HGNC:25531|Ensembl:ENSG00000064763|Vega:OTTHUMG00000169320 +55713 ZNF334 HGNC:HGNC:15806|Ensembl:ENSG00000198185|Vega:OTTHUMG00000032654 +55714 TENM3 MIM:610083|HGNC:HGNC:29944|Ensembl:ENSG00000218336|Vega:OTTHUMG00000160682 +55715 DOK4 MIM:608333|HGNC:HGNC:19868|Ensembl:ENSG00000125170|Vega:OTTHUMG00000133460 +55716 LMBR1L MIM:610007|HGNC:HGNC:18268|Ensembl:ENSG00000139636|Vega:OTTHUMG00000150511 +55717 WDR11 MIM:606417|HGNC:HGNC:13831|Ensembl:ENSG00000120008|Vega:OTTHUMG00000019171 +55718 POLR3E HGNC:HGNC:30347|Ensembl:ENSG00000058600|Vega:OTTHUMG00000094779 +55719 SLF2 MIM:610348|HGNC:HGNC:17814|Ensembl:ENSG00000119906|Vega:OTTHUMG00000018919 +55720 TSR1 MIM:611214|HGNC:HGNC:25542|Ensembl:ENSG00000167721|Vega:OTTHUMG00000177636 +55721 IQCC HGNC:HGNC:25545|Ensembl:ENSG00000160051|Vega:OTTHUMG00000005739 +55722 CEP72 MIM:616475|HGNC:HGNC:25547|Ensembl:ENSG00000112877|Vega:OTTHUMG00000161745 +55723 ASF1B MIM:609190|HGNC:HGNC:20996|Ensembl:ENSG00000105011|Vega:OTTHUMG00000150401 +55726 INTS13 MIM:615079|HGNC:HGNC:20174|Ensembl:ENSG00000064102|Vega:OTTHUMG00000169193 +55727 BTBD7 MIM:610386|HGNC:HGNC:18269|Ensembl:ENSG00000011114|Vega:OTTHUMG00000171269 +55728 N4BP2 HGNC:HGNC:29851|Ensembl:ENSG00000078177|Vega:OTTHUMG00000128599 +55729 ATF7IP MIM:613644|HGNC:HGNC:20092|Ensembl:ENSG00000171681|Vega:OTTHUMG00000168656 +55731 FAM222B HGNC:HGNC:25563|Ensembl:ENSG00000173065|Vega:OTTHUMG00000179495 +55732 C1orf112 HGNC:HGNC:25565|Ensembl:ENSG00000000460|Vega:OTTHUMG00000035821 +55733 HHAT MIM:605743|HGNC:HGNC:18270|Ensembl:ENSG00000054392|Vega:OTTHUMG00000036447 +55734 ZFP64 HGNC:HGNC:15940|Ensembl:ENSG00000020256|Vega:OTTHUMG00000032756 +55735 DNAJC11 MIM:614827|HGNC:HGNC:25570|Ensembl:ENSG00000007923|Vega:OTTHUMG00000001443 +55737 VPS35 MIM:601501|HGNC:HGNC:13487|Ensembl:ENSG00000069329|Vega:OTTHUMG00000132542 +55738 ARFGAP1 MIM:608377|HGNC:HGNC:15852|Ensembl:ENSG00000101199|Vega:OTTHUMG00000032965 +55739 NAXD MIM:615910|HGNC:HGNC:25576|Ensembl:ENSG00000213995|Vega:OTTHUMG00000017345 +55740 ENAH MIM:609061|HGNC:HGNC:18271|Ensembl:ENSG00000154380|Vega:OTTHUMG00000037742 +55741 EDEM2 MIM:610302|HGNC:HGNC:15877|Ensembl:ENSG00000088298|Vega:OTTHUMG00000032322 +55742 PARVA MIM:608120|HGNC:HGNC:14652|Ensembl:ENSG00000197702|Vega:OTTHUMG00000165778 +55743 CHFR MIM:605209|HGNC:HGNC:20455|Ensembl:ENSG00000072609|Vega:OTTHUMG00000167930 +55744 COA1 MIM:614769|HGNC:HGNC:21868|Ensembl:ENSG00000106603|Vega:OTTHUMG00000128949 +55745 AP5M1 MIM:614368|HGNC:HGNC:20192|Ensembl:ENSG00000053770|Vega:OTTHUMG00000140318 +55746 NUP133 MIM:607613|HGNC:HGNC:18016|Ensembl:ENSG00000069248|Vega:OTTHUMG00000039462 +55748 CNDP2 MIM:169800|HGNC:HGNC:24437|Ensembl:ENSG00000133313|Vega:OTTHUMG00000132853 +55749 CCAR1 MIM:612569|HGNC:HGNC:24236|Ensembl:ENSG00000060339|Vega:OTTHUMG00000018361 +55750 AGK MIM:610345|HGNC:HGNC:21869|Ensembl:ENSG00000006530|Vega:OTTHUMG00000157499 +55751 TMEM184C MIM:613937|HGNC:HGNC:25587|Ensembl:ENSG00000164168|Vega:OTTHUMG00000161358 +55752 SEPT11 MIM:612887|HGNC:HGNC:25589|Ensembl:ENSG00000138758|Vega:OTTHUMG00000160854 +55753 OGDHL MIM:617513|HGNC:HGNC:25590|Ensembl:ENSG00000197444|Vega:OTTHUMG00000018200 +55754 TMEM30A MIM:611028|HGNC:HGNC:16667|Ensembl:ENSG00000112697|Vega:OTTHUMG00000015050 +55755 CDK5RAP2 MIM:608201|HGNC:HGNC:18672|Ensembl:ENSG00000136861|Vega:OTTHUMG00000021043 +55756 INTS9 MIM:611352|HGNC:HGNC:25592|Ensembl:ENSG00000104299|Vega:OTTHUMG00000164030 +55757 UGGT2 MIM:605898|HGNC:HGNC:15664|Ensembl:ENSG00000102595|Vega:OTTHUMG00000017230 +55758 RCOR3 HGNC:HGNC:25594|Ensembl:ENSG00000117625|Vega:OTTHUMG00000036996 +55759 WDR12 MIM:616620|HGNC:HGNC:14098|Ensembl:ENSG00000138442|Vega:OTTHUMG00000132855 +55760 DHX32 MIM:607960|HGNC:HGNC:16717|Ensembl:ENSG00000089876|Vega:OTTHUMG00000019238 +55761 TTC17 HGNC:HGNC:25596|Ensembl:ENSG00000052841|Vega:OTTHUMG00000166398 +55762 ZNF701 HGNC:HGNC:25597|Ensembl:ENSG00000167562|Vega:OTTHUMG00000182754 +55763 EXOC1 MIM:607879|HGNC:HGNC:30380|Ensembl:ENSG00000090989|Vega:OTTHUMG00000102165 +55764 IFT122 MIM:606045|HGNC:HGNC:13556|Ensembl:ENSG00000163913|Vega:OTTHUMG00000159516 +55765 C1orf106 HGNC:HGNC:25599|Ensembl:ENSG00000163362|Vega:OTTHUMG00000035789 +55766 H2AFJ HGNC:HGNC:14456|Ensembl:ENSG00000246705|Vega:OTTHUMG00000168736 +55768 NGLY1 MIM:610661|HGNC:HGNC:17646|Ensembl:ENSG00000151092|Vega:OTTHUMG00000155600 +55769 ZNF83 MIM:194558|HGNC:HGNC:13158|Ensembl:ENSG00000167766|Vega:OTTHUMG00000182761 +55770 EXOC2 MIM:615329|HGNC:HGNC:24968|Ensembl:ENSG00000112685|Vega:OTTHUMG00000137437 +55771 PRR11 MIM:615920|HGNC:HGNC:25619|Ensembl:ENSG00000068489|Vega:OTTHUMG00000179362 +55773 TBC1D23 HGNC:HGNC:25622|Ensembl:ENSG00000036054|Vega:OTTHUMG00000159067 +55775 TDP1 MIM:607198|HGNC:HGNC:18884|Ensembl:ENSG00000042088|Vega:OTTHUMG00000171016 +55776 SAYSD1 HGNC:HGNC:21025|Ensembl:ENSG00000112167|Vega:OTTHUMG00000014641 +55777 MBD5 MIM:611472|HGNC:HGNC:20444|Ensembl:ENSG00000204406|Vega:OTTHUMG00000150440 +55778 ZNF839 HGNC:HGNC:20345|Ensembl:ENSG00000022976|Vega:OTTHUMG00000171864 +55779 CFAP44 MIM:617559|HGNC:HGNC:25631|Ensembl:ENSG00000206530|Vega:OTTHUMG00000159259 +55780 ERMARD MIM:615532|HGNC:HGNC:21056|Ensembl:ENSG00000130023|Vega:OTTHUMG00000016067 +55781 RIOK2 HGNC:HGNC:18999|Ensembl:ENSG00000058729|Vega:OTTHUMG00000128723 +55783 CMTR2 MIM:616190|HGNC:HGNC:25635|Ensembl:ENSG00000180917|Vega:OTTHUMG00000137587 +55784 MCTP2 MIM:616297|HGNC:HGNC:25636|Ensembl:ENSG00000140563|Vega:OTTHUMG00000171751 +55785 FGD6 MIM:613520|HGNC:HGNC:21740|Ensembl:ENSG00000180263|Vega:OTTHUMG00000170133 +55786 ZNF415 HGNC:HGNC:20636|Ensembl:ENSG00000170954|Vega:OTTHUMG00000182865 +55787 TXLNG MIM:300677|HGNC:HGNC:18578|Ensembl:ENSG00000086712|Vega:OTTHUMG00000021196 +55788 LMBRD1 MIM:612625|HGNC:HGNC:23038|Ensembl:ENSG00000168216|Vega:OTTHUMG00000014985 +55789 DEPDC1B MIM:616073|HGNC:HGNC:24902|Ensembl:ENSG00000035499|Vega:OTTHUMG00000097083 +55790 CSGALNACT1 MIM:616615|HGNC:HGNC:24290|Ensembl:ENSG00000147408|Vega:OTTHUMG00000130827 +55791 LRIF1 MIM:615354|HGNC:HGNC:30299|Ensembl:ENSG00000121931|Vega:OTTHUMG00000011913 +55793 MINDY1 HGNC:HGNC:25648|Ensembl:ENSG00000143409|Vega:OTTHUMG00000035061 +55794 DDX28 MIM:607618|HGNC:HGNC:17330|Ensembl:ENSG00000182810|Vega:OTTHUMG00000137549 +55795 PCID2 MIM:613713|HGNC:HGNC:25653|Ensembl:ENSG00000126226|Vega:OTTHUMG00000017385 +55796 MBNL3 MIM:300413|HGNC:HGNC:20564|Ensembl:ENSG00000076770|Vega:OTTHUMG00000022426 +55798 METTL2B MIM:607846|HGNC:HGNC:18272|Ensembl:ENSG00000165055|Vega:OTTHUMG00000143738 +55799 CACNA2D3 MIM:606399|HGNC:HGNC:15460|Ensembl:ENSG00000157445|Vega:OTTHUMG00000158580 +55800 SCN3B MIM:608214|HGNC:HGNC:20665|Ensembl:ENSG00000166257|Vega:OTTHUMG00000166006 +55801 IL26 MIM:605679|HGNC:HGNC:17119|Ensembl:ENSG00000111536|Vega:OTTHUMG00000169114 +55802 DCP1A MIM:607010|HGNC:HGNC:18714|Ensembl:ENSG00000272886|Vega:OTTHUMG00000158193 +55803 ADAP2 MIM:608635|HGNC:HGNC:16487|Ensembl:ENSG00000184060|Vega:OTTHUMG00000132868 +55805 LRP2BP HGNC:HGNC:25434|Ensembl:ENSG00000109771|Vega:OTTHUMG00000160460 +55806 HR MIM:602302|HGNC:HGNC:5172|Ensembl:ENSG00000168453|Vega:OTTHUMG00000097089 +55808 ST6GALNAC1 MIM:610138|HGNC:HGNC:23614|Ensembl:ENSG00000070526|Vega:OTTHUMG00000180369 +55809 TRERF1 MIM:610322|HGNC:HGNC:18273|Ensembl:ENSG00000124496|Vega:OTTHUMG00000014698 +55810 FOXJ2 HGNC:HGNC:24818|Ensembl:ENSG00000065970|Vega:OTTHUMG00000168526 +55811 ADCY10 MIM:605205|HGNC:HGNC:21285|Ensembl:ENSG00000143199|Vega:OTTHUMG00000034573 +55812 SPATA7 MIM:609868|HGNC:HGNC:20423|Ensembl:ENSG00000042317|Vega:OTTHUMG00000170744 +55813 UTP6 HGNC:HGNC:18279|Ensembl:ENSG00000108651|Vega:OTTHUMG00000132815 +55814 BDP1 MIM:607012|HGNC:HGNC:13652|Ensembl:ENSG00000145734|Vega:OTTHUMG00000162506 +55815 TSNAXIP1 MIM:607720|HGNC:HGNC:18586|Ensembl:ENSG00000102904|Vega:OTTHUMG00000137545 +55816 DOK5 MIM:608334|HGNC:HGNC:16173|Ensembl:ENSG00000101134|Vega:OTTHUMG00000032778 +55818 KDM3A MIM:611512|HGNC:HGNC:20815|Ensembl:ENSG00000115548|Vega:OTTHUMG00000130204 +55819 RNF130 HGNC:HGNC:18280|Ensembl:ENSG00000113269|Vega:OTTHUMG00000130909 +55821 ALLC MIM:612396|HGNC:HGNC:17377|Ensembl:ENSG00000151360|Vega:OTTHUMG00000151485 +55823 VPS11 MIM:608549|HGNC:HGNC:14583|Ensembl:ENSG00000160695|Vega:OTTHUMG00000166355 +55824 PAG1 MIM:605767|HGNC:HGNC:30043|Ensembl:ENSG00000076641|Vega:OTTHUMG00000164592 +55825 PECR MIM:605843|HGNC:HGNC:18281|Ensembl:ENSG00000115425|Vega:OTTHUMG00000154825 +55827 DCAF6 MIM:610494|HGNC:HGNC:30002|Ensembl:ENSG00000143164|Vega:OTTHUMG00000034572 +55829 SELENOS MIM:607918|HGNC:HGNC:30396|Ensembl:ENSG00000131871|Vega:OTTHUMG00000166441 +55830 GLT8D1 HGNC:HGNC:24870|Ensembl:ENSG00000016864|Vega:OTTHUMG00000158759 +55831 EMC3 HGNC:HGNC:23999|Ensembl:ENSG00000125037|Vega:OTTHUMG00000128652 +55832 CAND1 MIM:607727|HGNC:HGNC:30688|Ensembl:ENSG00000111530|Vega:OTTHUMG00000169060 +55833 UBAP2 HGNC:HGNC:14185|Ensembl:ENSG00000137073|Vega:OTTHUMG00000000427 +55835 CENPJ MIM:609279|HGNC:HGNC:17272|Ensembl:ENSG00000151849|Vega:OTTHUMG00000016595 +55837 EAPP MIM:609486|HGNC:HGNC:19312|Ensembl:ENSG00000129518|Vega:OTTHUMG00000170621 +55839 CENPN MIM:611509|HGNC:HGNC:30873|Ensembl:ENSG00000166451|Vega:OTTHUMG00000137628 +55840 EAF2 MIM:607659|HGNC:HGNC:23115|Ensembl:ENSG00000145088|Vega:OTTHUMG00000159424 +55841 WWC3 HGNC:HGNC:29237|Ensembl:ENSG00000047644|Vega:OTTHUMG00000021123 +55843 ARHGAP15 MIM:610578|HGNC:HGNC:21030|Ensembl:ENSG00000075884|Vega:OTTHUMG00000131845 +55844 PPP2R2D MIM:613992|HGNC:HGNC:23732|Ensembl:ENSG00000175470|Vega:OTTHUMG00000019277 +55845 BRK1 MIM:611183|HGNC:HGNC:23057|Ensembl:ENSG00000254999|Vega:OTTHUMG00000155400 +55846 ITFG2 MIM:617421|HGNC:HGNC:30879|Ensembl:ENSG00000111203|Vega:OTTHUMG00000130617 +55847 CISD1 MIM:611932|HGNC:HGNC:30880|Ensembl:ENSG00000122873|Vega:OTTHUMG00000018266 +55848 PLGRKT HGNC:HGNC:23633|Ensembl:ENSG00000107020|Vega:OTTHUMG00000019501 +55850 USE1 MIM:610675|HGNC:HGNC:30882|Ensembl:ENSG00000053501|Vega:OTTHUMG00000182723 +55851 PSENEN MIM:607632|HGNC:HGNC:30100|Ensembl:ENSG00000205155|Vega:OTTHUMG00000182067 +55852 TEX2 HGNC:HGNC:30884|Ensembl:ENSG00000136478|Vega:OTTHUMG00000178881 +55853 IDI2-AS1 MIM:615391|HGNC:HGNC:30885|Ensembl:ENSG00000232656 +55854 ZC3H15 HGNC:HGNC:29528|Ensembl:ENSG00000065548|Vega:OTTHUMG00000154251 +55855 FAM45BP HGNC:HGNC:30886 +55856 ACOT13 MIM:615652|HGNC:HGNC:20999|Ensembl:ENSG00000112304|Vega:OTTHUMG00000014359 +55857 KIZ MIM:615757|HGNC:HGNC:15865|Ensembl:ENSG00000088970|Vega:OTTHUMG00000032020 +55858 TMEM165 MIM:614726|HGNC:HGNC:30760|Ensembl:ENSG00000134851|Vega:OTTHUMG00000128735 +55859 BEX1 MIM:300690|HGNC:HGNC:1036|Ensembl:ENSG00000133169|Vega:OTTHUMG00000022708 +55860 ACTR10 HGNC:HGNC:17372|Ensembl:ENSG00000131966|Vega:OTTHUMG00000171049 +55861 DBNDD2 MIM:611453|HGNC:HGNC:15881|Ensembl:ENSG00000244274|Vega:OTTHUMG00000032576 +55862 ECHDC1 MIM:612136|HGNC:HGNC:21489|Ensembl:ENSG00000093144|Vega:OTTHUMG00000015523 +55863 TMEM126B MIM:615533|HGNC:HGNC:30883|Ensembl:ENSG00000171204|Vega:OTTHUMG00000166974 +55867 SLC22A11 MIM:607097|HGNC:HGNC:18120|Ensembl:ENSG00000168065|Vega:OTTHUMG00000045142 +55869 HDAC8 MIM:300269|HGNC:HGNC:13315|Ensembl:ENSG00000147099|Vega:OTTHUMG00000021814 +55870 ASH1L MIM:607999|HGNC:HGNC:19088|Ensembl:ENSG00000116539|Vega:OTTHUMG00000014011 +55871 CBWD1 MIM:611078|HGNC:HGNC:17134|Ensembl:ENSG00000172785|Vega:OTTHUMG00000019425 +55872 PBK MIM:611210|HGNC:HGNC:18282|Ensembl:ENSG00000168078|Vega:OTTHUMG00000102113 +55876 GSDMB MIM:611221|HGNC:HGNC:23690|Ensembl:ENSG00000073605|Vega:OTTHUMG00000133248 +55879 GABRQ MIM:300349|HGNC:HGNC:14454|Ensembl:ENSG00000268089|Vega:OTTHUMG00000022649 +55884 WSB2 HGNC:HGNC:19222|Ensembl:ENSG00000176871|Vega:OTTHUMG00000168885 +55885 LMO3 MIM:180386|HGNC:HGNC:6643|Ensembl:ENSG00000048540|Vega:OTTHUMG00000168837 +55888 ZKSCAN7 HGNC:HGNC:12955|Ensembl:ENSG00000196345|Vega:OTTHUMG00000186378 +55889 GOLGA6B HGNC:HGNC:32205|Ensembl:ENSG00000215186|Vega:OTTHUMG00000133511 +55890 GPRC5C MIM:605949|HGNC:HGNC:13309|Ensembl:ENSG00000170412|Vega:OTTHUMG00000067613 +55891 LENEP MIM:607377|HGNC:HGNC:14429|Ensembl:ENSG00000163352|Vega:OTTHUMG00000037417 +55892 MYNN MIM:606042|HGNC:HGNC:14955|Ensembl:ENSG00000085274|Vega:OTTHUMG00000184027 +55893 ZNF395 MIM:609494|HGNC:HGNC:18737|Ensembl:ENSG00000186918|Vega:OTTHUMG00000102137 +55894 DEFB103B MIM:606611|HGNC:HGNC:31702|Ensembl:ENSG00000177243|Vega:OTTHUMG00000129313 +55897 MESP1 MIM:608689|HGNC:HGNC:29658|Ensembl:ENSG00000166823|Vega:OTTHUMG00000149810 +55898 UNC45A MIM:611219|HGNC:HGNC:30594|Ensembl:ENSG00000140553|Vega:OTTHUMG00000141261 +55900 ZNF302 HGNC:HGNC:13848|Ensembl:ENSG00000089335|Vega:OTTHUMG00000163329 +55901 THSD1 MIM:616821|HGNC:HGNC:17754|Ensembl:ENSG00000136114|Vega:OTTHUMG00000016963 +55902 ACSS2 MIM:605832|HGNC:HGNC:15814|Ensembl:ENSG00000131069|Vega:OTTHUMG00000032317 +55904 KMT2E MIM:608444|HGNC:HGNC:18541|Ensembl:ENSG00000005483|Vega:OTTHUMG00000157403 +55905 RNF114 MIM:612451|HGNC:HGNC:13094|Ensembl:ENSG00000124226|Vega:OTTHUMG00000032709 +55906 ZC4H2 MIM:300897|HGNC:HGNC:24931|Ensembl:ENSG00000126970|Vega:OTTHUMG00000021712 +55907 CMAS MIM:603316|HGNC:HGNC:18290|Ensembl:ENSG00000111726|Vega:OTTHUMG00000169097 +55908 ANGPTL8 MIM:616223|HGNC:HGNC:24933|Ensembl:ENSG00000130173|Vega:OTTHUMG00000180829 +55909 BIN3 MIM:606396|HGNC:HGNC:1054|Ensembl:ENSG00000147439|Vega:OTTHUMG00000163844 +55911 APOBR MIM:605220|HGNC:HGNC:24087|Ensembl:ENSG00000184730|Vega:OTTHUMG00000172705 +55914 ERBIN MIM:606944|HGNC:HGNC:15842|Ensembl:ENSG00000112851|Vega:OTTHUMG00000097808 +55915 LANCL2 MIM:612919|HGNC:HGNC:6509|Ensembl:ENSG00000132434|Vega:OTTHUMG00000023779 +55916 NXT2 MIM:300320|HGNC:HGNC:18151|Ensembl:ENSG00000101888|Vega:OTTHUMG00000022185 +55917 CTTNBP2NL MIM:615100|HGNC:HGNC:25330|Ensembl:ENSG00000143079|Vega:OTTHUMG00000011154 +55920 RCC2 MIM:609587|HGNC:HGNC:30297|Ensembl:ENSG00000179051|Vega:OTTHUMG00000002513 +55922 NKRF MIM:300440|HGNC:HGNC:19374|Ensembl:ENSG00000186416|Vega:OTTHUMG00000022277 +55924 FAM212B HGNC:HGNC:28045|Ensembl:ENSG00000197852|Vega:OTTHUMG00000011953 +55929 DMAP1 MIM:605077|HGNC:HGNC:18291|Ensembl:ENSG00000178028|Vega:OTTHUMG00000007577 +55930 MYO5C MIM:610022|HGNC:HGNC:7604|Ensembl:ENSG00000128833|Vega:OTTHUMG00000172630 +55937 APOM MIM:606907|HGNC:HGNC:13916|Ensembl:ENSG00000204444|Vega:OTTHUMG00000031250 +55954 ZMAT5 HGNC:HGNC:28046|Ensembl:ENSG00000100319|Vega:OTTHUMG00000151292 +55957 LIN37 HGNC:HGNC:33234|Ensembl:ENSG00000267796|Vega:OTTHUMG00000182070 +55958 KLHL9 MIM:611201|HGNC:HGNC:18732|Ensembl:ENSG00000198642|Vega:OTTHUMG00000019669 +55959 SULF2 MIM:610013|HGNC:HGNC:20392|Ensembl:ENSG00000196562|Vega:OTTHUMG00000032675 +55964 SEPT3 MIM:608314|HGNC:HGNC:10750|Ensembl:ENSG00000100167|Vega:OTTHUMG00000030494 +55966 AJAP1 MIM:610972|HGNC:HGNC:30801|Ensembl:ENSG00000196581|Vega:OTTHUMG00000000645 +55967 NDUFA12 MIM:614530|HGNC:HGNC:23987|Ensembl:ENSG00000184752|Vega:OTTHUMG00000170098 +55968 NSFL1C MIM:606610|HGNC:HGNC:15912|Ensembl:ENSG00000088833|Vega:OTTHUMG00000031665 +55969 C20orf24 HGNC:HGNC:15870|Ensembl:ENSG00000101084|Vega:OTTHUMG00000032384 +55970 GNG12 MIM:615405|HGNC:HGNC:19663|Ensembl:ENSG00000172380|Vega:OTTHUMG00000009545 +55971 BAIAP2L1 MIM:611877|HGNC:HGNC:21649|Ensembl:ENSG00000006453|Vega:OTTHUMG00000165117 +55972 SLC25A40 MIM:610821|HGNC:HGNC:29680|Ensembl:ENSG00000075303|Vega:OTTHUMG00000131033 +55973 BCAP29 HGNC:HGNC:24131|Ensembl:ENSG00000075790|Vega:OTTHUMG00000154770 +55974 SLC50A1 MIM:613683|HGNC:HGNC:30657|Ensembl:ENSG00000169241|Vega:OTTHUMG00000035333 +55975 KLHL7 MIM:611119|HGNC:HGNC:15646|Ensembl:ENSG00000122550|Vega:OTTHUMG00000094813 +55997 CFC1 MIM:605194|HGNC:HGNC:18292|Ensembl:ENSG00000136698|Vega:OTTHUMG00000131628 +55998 NXF5 MIM:300319|HGNC:HGNC:8075|Ensembl:ENSG00000126952|Vega:OTTHUMG00000022042 +55999 NXF4 MIM:300318|HGNC:HGNC:8074|Ensembl:ENSG00000196970 +56000 NXF3 MIM:300316|HGNC:HGNC:8073|Ensembl:ENSG00000147206|Vega:OTTHUMG00000022088 +56001 NXF2 MIM:300315|HGNC:HGNC:8072|Ensembl:ENSG00000269405|Vega:OTTHUMG00000189320 +56005 MYDGF MIM:606746|HGNC:HGNC:16948|Ensembl:ENSG00000074842|Vega:OTTHUMG00000182039 +56006 SMG9 MIM:613176|HGNC:HGNC:25763|Ensembl:ENSG00000105771|Vega:OTTHUMG00000150337 +56033 BARX1 MIM:603260|HGNC:HGNC:955|Ensembl:ENSG00000131668|Vega:OTTHUMG00000020255 +56034 PDGFC MIM:608452|HGNC:HGNC:8801|Ensembl:ENSG00000145431|Vega:OTTHUMG00000161803 +56052 ALG1 MIM:605907|HGNC:HGNC:18294|Ensembl:ENSG00000033011|Vega:OTTHUMG00000129529 +56061 UBFD1 HGNC:HGNC:30565|Ensembl:ENSG00000103353|Vega:OTTHUMG00000128855 +56062 KLHL4 MIM:300348|HGNC:HGNC:6355|Ensembl:ENSG00000102271|Vega:OTTHUMG00000021946 +56063 TMEM234 HGNC:HGNC:28837|Ensembl:ENSG00000160055|Vega:OTTHUMG00000005742 +56097 PCDHGC5 MIM:606306|HGNC:HGNC:8718|Ensembl:ENSG00000240764|Vega:OTTHUMG00000129624 +56098 PCDHGC4 MIM:606305|HGNC:HGNC:8717|Ensembl:ENSG00000242419|Vega:OTTHUMG00000129625 +56099 PCDHGB7 MIM:606304|HGNC:HGNC:8714|Ensembl:ENSG00000254122|Vega:OTTHUMG00000164054 +56100 PCDHGB6 MIM:606303|HGNC:HGNC:8713|Ensembl:ENSG00000253305|Vega:OTTHUMG00000163687 +56101 PCDHGB5 MIM:606302|HGNC:HGNC:8712|Ensembl:ENSG00000276547|Vega:OTTHUMG00000188231 +56102 PCDHGB3 MIM:606301|HGNC:HGNC:8710|Ensembl:ENSG00000262209|Vega:OTTHUMG00000177471 +56103 PCDHGB2 MIM:606300|HGNC:HGNC:8709|Ensembl:ENSG00000253910|Vega:OTTHUMG00000163682 +56104 PCDHGB1 MIM:606299|HGNC:HGNC:8708|Ensembl:ENSG00000254221|Vega:OTTHUMG00000163681 +56105 PCDHGA11 MIM:606298|HGNC:HGNC:8698|Ensembl:ENSG00000253873|Vega:OTTHUMG00000164055 +56106 PCDHGA10 MIM:606297|HGNC:HGNC:8697|Ensembl:ENSG00000253846|Vega:OTTHUMG00000163688 +56107 PCDHGA9 MIM:606296|HGNC:HGNC:8707|Ensembl:ENSG00000261934|Vega:OTTHUMG00000177473 +56108 PCDHGA7 MIM:606294|HGNC:HGNC:8705|Ensembl:ENSG00000253537|Vega:OTTHUMG00000163685 +56109 PCDHGA6 MIM:606293|HGNC:HGNC:8704|Ensembl:ENSG00000253731|Vega:OTTHUMG00000163684 +56110 PCDHGA5 MIM:606292|HGNC:HGNC:8703|Ensembl:ENSG00000253485|Vega:OTTHUMG00000163683 +56111 PCDHGA4 MIM:606291|HGNC:HGNC:8702|Ensembl:ENSG00000262576|Vega:OTTHUMG00000177593 +56112 PCDHGA3 MIM:606290|HGNC:HGNC:8701|Ensembl:ENSG00000254245|Vega:OTTHUMG00000163680 +56113 PCDHGA2 MIM:606289|HGNC:HGNC:8700|Ensembl:ENSG00000081853|Vega:OTTHUMG00000163679 +56114 PCDHGA1 MIM:606288|HGNC:HGNC:8696|Ensembl:ENSG00000204956|Vega:OTTHUMG00000163678 +56115 PCDHG@ MIM:604968|HGNC:HGNC:8695 +56116 PCDHB@ MIM:604967|HGNC:HGNC:8679 +56117 PCDHA@ MIM:604966|HGNC:HGNC:8662 +56118 PCDHGCT HGNC:HGNC:8719 +56119 PCDHACT HGNC:HGNC:8678 +56120 PCDHGB8P HGNC:HGNC:8715|Ensembl:ENSG00000248449 +56121 PCDHB15 MIM:606341|HGNC:HGNC:8686|Ensembl:ENSG00000113248|Vega:OTTHUMG00000129609 +56122 PCDHB14 MIM:606340|HGNC:HGNC:8685|Ensembl:ENSG00000120327|Vega:OTTHUMG00000129619 +56123 PCDHB13 MIM:606339|HGNC:HGNC:8684|Ensembl:ENSG00000187372|Vega:OTTHUMG00000129615 +56124 PCDHB12 MIM:606338|HGNC:HGNC:8683|Ensembl:ENSG00000120328|Vega:OTTHUMG00000129620 +56125 PCDHB11 MIM:606337|HGNC:HGNC:8682|Ensembl:ENSG00000197479|Vega:OTTHUMG00000129618 +56126 PCDHB10 MIM:606336|HGNC:HGNC:8681|Ensembl:ENSG00000120324|Vega:OTTHUMG00000129626 +56127 PCDHB9 MIM:606335|HGNC:HGNC:8694|Ensembl:ENSG00000177839|Vega:OTTHUMG00000188326 +56128 PCDHB8 MIM:606334|HGNC:HGNC:8693|Ensembl:ENSG00000120322|Vega:OTTHUMG00000129621 +56129 PCDHB7 MIM:606333|HGNC:HGNC:8692|Ensembl:ENSG00000113212|Vega:OTTHUMG00000129608 +56130 PCDHB6 MIM:606332|HGNC:HGNC:8691|Ensembl:ENSG00000113211|Vega:OTTHUMG00000129623 +56131 PCDHB4 MIM:606330|HGNC:HGNC:8689|Ensembl:ENSG00000081818|Vega:OTTHUMG00000129617 +56132 PCDHB3 MIM:606329|HGNC:HGNC:8688|Ensembl:ENSG00000113205|Vega:OTTHUMG00000129622 +56133 PCDHB2 MIM:606328|HGNC:HGNC:8687|Ensembl:ENSG00000112852|Vega:OTTHUMG00000129606 +56134 PCDHAC2 MIM:606321|HGNC:HGNC:8677|Ensembl:ENSG00000243232|Vega:OTTHUMG00000129607 +56135 PCDHAC1 MIM:606320|HGNC:HGNC:8676|Ensembl:ENSG00000248383|Vega:OTTHUMG00000129603 +56136 PCDHA13 MIM:606319|HGNC:HGNC:8667|Ensembl:ENSG00000239389|Vega:OTTHUMG00000129614 +56137 PCDHA12 MIM:606318|HGNC:HGNC:8666|Ensembl:ENSG00000251664|Vega:OTTHUMG00000163366 +56138 PCDHA11 MIM:606317|HGNC:HGNC:8665|Ensembl:ENSG00000249158|Vega:OTTHUMG00000163369 +56139 PCDHA10 MIM:606316|HGNC:HGNC:8664|Ensembl:ENSG00000250120|Vega:OTTHUMG00000163372 +56140 PCDHA8 MIM:606314|HGNC:HGNC:8674|Ensembl:ENSG00000204962|Vega:OTTHUMG00000163354 +56141 PCDHA7 MIM:606313|HGNC:HGNC:8673|Ensembl:ENSG00000204963|Vega:OTTHUMG00000163371 +56142 PCDHA6 MIM:606312|HGNC:HGNC:8672|Ensembl:ENSG00000081842|Vega:OTTHUMG00000163353 +56143 PCDHA5 MIM:606311|HGNC:HGNC:8671|Ensembl:ENSG00000204965|Vega:OTTHUMG00000163367 +56144 PCDHA4 MIM:606310|HGNC:HGNC:8670|Ensembl:ENSG00000204967|Vega:OTTHUMG00000163360 +56145 PCDHA3 MIM:606309|HGNC:HGNC:8669|Ensembl:ENSG00000255408|Vega:OTTHUMG00000163357 +56146 PCDHA2 MIM:606308|HGNC:HGNC:8668|Ensembl:ENSG00000204969|Vega:OTTHUMG00000163363 +56147 PCDHA1 MIM:606307|HGNC:HGNC:8663|Ensembl:ENSG00000204970|Vega:OTTHUMG00000163368 +56154 TEX15 MIM:605795|HGNC:HGNC:11738|Ensembl:ENSG00000133863|Vega:OTTHUMG00000163881 +56155 TEX14 MIM:605792|HGNC:HGNC:11737|Ensembl:ENSG00000121101|Vega:OTTHUMG00000179245 +56156 TEX13B MIM:300313|HGNC:HGNC:11736|Ensembl:ENSG00000170925|Vega:OTTHUMG00000022174 +56157 TEX13A MIM:300312|HGNC:HGNC:11735|Ensembl:ENSG00000268629|Vega:OTTHUMG00000022133 +56158 TEX12 MIM:605791|HGNC:HGNC:11734|Ensembl:ENSG00000150783|Vega:OTTHUMG00000167008 +56159 TEX11 MIM:300311|HGNC:HGNC:11733|Ensembl:ENSG00000120498|Vega:OTTHUMG00000021782 +56160 NSMCE3 MIM:608243|HGNC:HGNC:7677|Ensembl:ENSG00000185115|Vega:OTTHUMG00000129261 +56163 RNF17 MIM:605793|HGNC:HGNC:10060|Ensembl:ENSG00000132972|Vega:OTTHUMG00000016589 +56164 STK31 MIM:605790|HGNC:HGNC:11407|Ensembl:ENSG00000196335|Vega:OTTHUMG00000023053 +56165 TDRD1 MIM:605796|HGNC:HGNC:11712|Ensembl:ENSG00000095627|Vega:OTTHUMG00000019083 +56167 MTCO1P1 HGNC:HGNC:7420 +56168 MTND2P2 HGNC:HGNC:23767 +56169 GSDMC MIM:608384|HGNC:HGNC:7151|Ensembl:ENSG00000147697|Vega:OTTHUMG00000164851 +56171 DNAH7 MIM:610061|HGNC:HGNC:18661|Ensembl:ENSG00000118997|Vega:OTTHUMG00000154438 +56172 ANKH MIM:605145|HGNC:HGNC:15492|Ensembl:ENSG00000154122|Vega:OTTHUMG00000090539 +56180 MOSPD1 MIM:300674|HGNC:HGNC:25235|Ensembl:ENSG00000101928|Vega:OTTHUMG00000035315 +56181 MTFR1L HGNC:HGNC:28836|Ensembl:ENSG00000117640|Vega:OTTHUMG00000007377 +56203 LMOD3 MIM:616112|HGNC:HGNC:6649|Ensembl:ENSG00000163380|Vega:OTTHUMG00000158774 +56204 FAM214A HGNC:HGNC:25609|Ensembl:ENSG00000047346|Vega:OTTHUMG00000172688 +56241 SUSD2 MIM:615825|HGNC:HGNC:30667|Ensembl:ENSG00000099994|Vega:OTTHUMG00000150792 +56242 ZNF253 MIM:606954|HGNC:HGNC:13497|Ensembl:ENSG00000256771|Vega:OTTHUMG00000182369 +56243 KIAA1217 MIM:617367|HGNC:HGNC:25428|Ensembl:ENSG00000120549|Vega:OTTHUMG00000017824 +56244 BTNL2 MIM:606000|HGNC:HGNC:1142|Ensembl:ENSG00000204290|Vega:OTTHUMG00000031102 +56245 C21orf62 HGNC:HGNC:1305|Ensembl:ENSG00000205929|Vega:OTTHUMG00000163477 +56246 MRAP MIM:609196|HGNC:HGNC:1304|Ensembl:ENSG00000170262|Vega:OTTHUMG00000085309 +56247 FMR3 HGNC:HGNC:3777 +56252 YLPM1 HGNC:HGNC:17798|Ensembl:ENSG00000119596|Vega:OTTHUMG00000172503 +56253 CRTAM MIM:612597|HGNC:HGNC:24313|Ensembl:ENSG00000109943|Vega:OTTHUMG00000166026 +56254 RNF20 MIM:607699|HGNC:HGNC:10062|Ensembl:ENSG00000155827|Vega:OTTHUMG00000020385 +56255 TMX4 MIM:616766|HGNC:HGNC:25237|Ensembl:ENSG00000125827|Vega:OTTHUMG00000031843 +56256 SERTAD4 HGNC:HGNC:25236|Ensembl:ENSG00000082497|Vega:OTTHUMG00000036391 +56257 MEPCE MIM:611478|HGNC:HGNC:20247|Ensembl:ENSG00000146834|Vega:OTTHUMG00000155255 +56259 CTNNBL1 MIM:611537|HGNC:HGNC:15879|Ensembl:ENSG00000132792|Vega:OTTHUMG00000032428 +56260 C8orf44 HGNC:HGNC:25646|Ensembl:ENSG00000213865|Vega:OTTHUMG00000164562 +56261 GPCPD1 MIM:614124|HGNC:HGNC:26957|Ensembl:ENSG00000125772|Vega:OTTHUMG00000031806 +56262 LRRC8A MIM:608360|HGNC:HGNC:19027|Ensembl:ENSG00000136802|Vega:OTTHUMG00000020766 +56265 CPXM1 MIM:609555|HGNC:HGNC:15771|Ensembl:ENSG00000088882|Vega:OTTHUMG00000031706 +56267 KYAT3 MIM:610656|HGNC:HGNC:33238|Ensembl:ENSG00000137944|Vega:OTTHUMG00000010617 +56269 IRGC HGNC:HGNC:28835|Ensembl:ENSG00000124449|Vega:OTTHUMG00000154587 +56270 WDR45B MIM:609226|HGNC:HGNC:25072|Ensembl:ENSG00000141580|Vega:OTTHUMG00000150146 +56271 BEX4 MIM:300692|HGNC:HGNC:25475|Ensembl:ENSG00000102409|Vega:OTTHUMG00000022091 +56286 DAD1P1 MIM:609860|HGNC:HGNC:18295 +56287 GKN1 MIM:606402|HGNC:HGNC:23217|Ensembl:ENSG00000169605|Vega:OTTHUMG00000129574 +56288 PARD3 MIM:606745|HGNC:HGNC:16051|Ensembl:ENSG00000148498|Vega:OTTHUMG00000017948 +56300 IL36G MIM:605542|HGNC:HGNC:15741|Ensembl:ENSG00000136688|Vega:OTTHUMG00000131336 +56301 SLC7A10 MIM:607959|HGNC:HGNC:11058|Ensembl:ENSG00000130876|Vega:OTTHUMG00000180344 +56302 TRPV5 MIM:606679|HGNC:HGNC:3145|Ensembl:ENSG00000127412|Vega:OTTHUMG00000157157 +56311 ANKRD7 MIM:610731|HGNC:HGNC:18588|Ensembl:ENSG00000106013|Vega:OTTHUMG00000156960 +56339 METTL3 MIM:612472|HGNC:HGNC:17563|Ensembl:ENSG00000165819|Vega:OTTHUMG00000168825 +56341 PRMT8 MIM:610086|HGNC:HGNC:5188|Ensembl:ENSG00000111218|Vega:OTTHUMG00000128493 +56342 PPAN MIM:607793|HGNC:HGNC:9227|Ensembl:ENSG00000130810|Vega:OTTHUMG00000156826 +56344 CABP5 MIM:607315|HGNC:HGNC:13714|Ensembl:ENSG00000105507|Vega:OTTHUMG00000183139 +56413 LTB4R2 MIM:605773|HGNC:HGNC:19260|Ensembl:ENSG00000213906|Vega:OTTHUMG00000186500 +56474 CTPS2 MIM:300380|HGNC:HGNC:2520|Ensembl:ENSG00000047230|Vega:OTTHUMG00000021193 +56475 RPRM MIM:612171|HGNC:HGNC:24201|Ensembl:ENSG00000177519|Vega:OTTHUMG00000131905 +56476 ABCB10P1 HGNC:HGNC:14114 +56477 CCL28 MIM:605240|HGNC:HGNC:17700|Ensembl:ENSG00000151882|Vega:OTTHUMG00000094811 +56478 EIF4ENIF1 MIM:607445|HGNC:HGNC:16687|Ensembl:ENSG00000184708|Vega:OTTHUMG00000030793 +56479 KCNQ5 MIM:607357|HGNC:HGNC:6299|Ensembl:ENSG00000185760|Vega:OTTHUMG00000015020 +56521 DNAJC12 MIM:606060|HGNC:HGNC:28908|Ensembl:ENSG00000108176|Vega:OTTHUMG00000018339 +56547 MMP26 MIM:605470|HGNC:HGNC:14249|Ensembl:ENSG00000167346|Vega:OTTHUMG00000066442 +56548 CHST7 MIM:300375|HGNC:HGNC:13817|Ensembl:ENSG00000147119|Vega:OTTHUMG00000021423 +56603 CYP26B1 MIM:605207|HGNC:HGNC:20581|Ensembl:ENSG00000003137|Vega:OTTHUMG00000129756 +56604 TUBB7P HGNC:HGNC:12413 +56605 ERO1B MIM:615437|HGNC:HGNC:14355|Ensembl:ENSG00000086619|Vega:OTTHUMG00000039955 +56606 SLC2A9 MIM:606142|HGNC:HGNC:13446|Ensembl:ENSG00000109667|Vega:OTTHUMG00000044263 +56616 DIABLO MIM:605219|HGNC:HGNC:21528|Ensembl:ENSG00000184047|Vega:OTTHUMG00000157014 +56623 INPP5E MIM:613037|HGNC:HGNC:21474|Ensembl:ENSG00000148384|Vega:OTTHUMG00000020927 +56624 ASAH2 MIM:611202|HGNC:HGNC:18860|Ensembl:ENSG00000188611|Vega:OTTHUMG00000018223 +56647 BCCIP MIM:611883|HGNC:HGNC:978|Ensembl:ENSG00000107949|Vega:OTTHUMG00000019237 +56648 EIF5A2 MIM:605782|HGNC:HGNC:3301|Ensembl:ENSG00000163577|Vega:OTTHUMG00000158958 +56649 TMPRSS4 MIM:606565|HGNC:HGNC:11878|Ensembl:ENSG00000137648|Vega:OTTHUMG00000164122 +56650 CLDND1 HGNC:HGNC:1322|Ensembl:ENSG00000080822|Vega:OTTHUMG00000160050 +56651 LINC00470 HGNC:HGNC:1225 +56652 TWNK MIM:606075|HGNC:HGNC:1160|Ensembl:ENSG00000107815|Vega:OTTHUMG00000018917 +56654 NPDC1 MIM:605798|HGNC:HGNC:7899|Ensembl:ENSG00000107281|Vega:OTTHUMG00000020956 +56655 POLE4 MIM:607269|HGNC:HGNC:18755|Ensembl:ENSG00000115350|Vega:OTTHUMG00000129971 +56656 OR2S2 HGNC:HGNC:8276|Ensembl:ENSG00000278889|Vega:OTTHUMG00000019891 +56658 TRIM39 MIM:605700|HGNC:HGNC:10065|Ensembl:ENSG00000204599|Vega:OTTHUMG00000031066 +56659 KCNK13 MIM:607367|HGNC:HGNC:6275|Ensembl:ENSG00000152315|Vega:OTTHUMG00000171017 +56660 KCNK12 MIM:607366|HGNC:HGNC:6274|Ensembl:ENSG00000184261|Vega:OTTHUMG00000129131 +56662 VTRNA1-3 MIM:612697|HGNC:HGNC:12656|Ensembl:ENSG00000202515 +56663 VTRNA1-2 MIM:612696|HGNC:HGNC:12655|Ensembl:ENSG00000202111 +56664 VTRNA1-1 MIM:612695|HGNC:HGNC:12654|Ensembl:ENSG00000199990 +56666 PANX2 MIM:608421|HGNC:HGNC:8600|Ensembl:ENSG00000073150|Vega:OTTHUMG00000044649 +56667 MUC13 MIM:612181|HGNC:HGNC:7511|Ensembl:ENSG00000173702|Vega:OTTHUMG00000159484 +56670 SUCNR1 MIM:606381|HGNC:HGNC:4542|Ensembl:ENSG00000198829|Vega:OTTHUMG00000159880 +56672 AKIP1 MIM:609191|HGNC:HGNC:1170|Ensembl:ENSG00000166452|Vega:OTTHUMG00000165653 +56673 C11orf16 HGNC:HGNC:1169|Ensembl:ENSG00000176029|Vega:OTTHUMG00000165654 +56674 TMEM9B HGNC:HGNC:1168|Ensembl:ENSG00000175348|Vega:OTTHUMG00000165676 +56675 NRIP3 MIM:613125|HGNC:HGNC:1167|Ensembl:ENSG00000175352|Vega:OTTHUMG00000165680 +56676 ASCL3 MIM:609154|HGNC:HGNC:740|Ensembl:ENSG00000176009|Vega:OTTHUMG00000165679 +56677 FABP3P2 HGNC:HGNC:3558 +56681 SAR1A MIM:607691|HGNC:HGNC:10534|Ensembl:ENSG00000079332|Vega:OTTHUMG00000018400 +56683 C21orf59 MIM:615494|HGNC:HGNC:1301|Ensembl:ENSG00000159079|Vega:OTTHUMG00000179510 +56694 BMIQ8 MIM:603188 +56704 JPH1 MIM:605266|HGNC:HGNC:14201|Ensembl:ENSG00000104369|Vega:OTTHUMG00000164524 +56729 RETN MIM:605565|HGNC:HGNC:20389|Ensembl:ENSG00000104918|Vega:OTTHUMG00000182503 +56731 SLC2A4RG MIM:609493|HGNC:HGNC:15930|Ensembl:ENSG00000125520|Vega:OTTHUMG00000032997 +56751 BARHL1 MIM:605211|HGNC:HGNC:953|Ensembl:ENSG00000125492|Vega:OTTHUMG00000020839 +56776 FMN2 MIM:606373|HGNC:HGNC:14074|Ensembl:ENSG00000155816|Vega:OTTHUMG00000039883 +56797 HTGS MIM:145750 +56801 HDLCQ14 MIM:605201 +56829 ZC3HAV1 MIM:607312|HGNC:HGNC:23721|Ensembl:ENSG00000105939|Vega:OTTHUMG00000157471 +56832 IFNK MIM:615326|HGNC:HGNC:21714|Ensembl:ENSG00000147896|Vega:OTTHUMG00000019715 +56833 SLAMF8 MIM:606620|HGNC:HGNC:21391|Ensembl:ENSG00000158714|Vega:OTTHUMG00000035433 +56834 GPR137 HGNC:HGNC:24300|Ensembl:ENSG00000173264|Vega:OTTHUMG00000167817 +56848 SPHK2 MIM:607092|HGNC:HGNC:18859|Ensembl:ENSG00000063176|Vega:OTTHUMG00000183318 +56849 TCEAL7 MIM:300771|HGNC:HGNC:28336|Ensembl:ENSG00000182916|Vega:OTTHUMG00000022096 +56850 GRIPAP1 MIM:300408|HGNC:HGNC:18706|Ensembl:ENSG00000068400|Vega:OTTHUMG00000033192 +56851 EMC7 HGNC:HGNC:24301|Ensembl:ENSG00000134153|Vega:OTTHUMG00000129367 +56852 RAD18 MIM:605256|HGNC:HGNC:18278|Ensembl:ENSG00000070950|Vega:OTTHUMG00000090545 +56853 CELF4 MIM:612679|HGNC:HGNC:14015|Ensembl:ENSG00000101489|Vega:OTTHUMG00000178178 +56882 CDC42SE1 HGNC:HGNC:17719|Ensembl:ENSG00000197622|Vega:OTTHUMG00000035158 +56884 FSTL5 HGNC:HGNC:21386|Ensembl:ENSG00000168843|Vega:OTTHUMG00000161397 +56886 UGGT1 MIM:605897|HGNC:HGNC:15663|Ensembl:ENSG00000136731|Vega:OTTHUMG00000131570 +56888 KCMF1 MIM:614719|HGNC:HGNC:20589|Ensembl:ENSG00000176407|Vega:OTTHUMG00000153004 +56889 TM9SF3 MIM:616872|HGNC:HGNC:21529|Ensembl:ENSG00000077147|Vega:OTTHUMG00000018834 +56890 MDM1 MIM:613813|HGNC:HGNC:29917|Ensembl:ENSG00000111554|Vega:OTTHUMG00000169136 +56891 LGALS14 MIM:607260|HGNC:HGNC:30054|Ensembl:ENSG00000006659|Vega:OTTHUMG00000183143 +56892 C8orf4 MIM:607702|HGNC:HGNC:1357|Ensembl:ENSG00000176907|Vega:OTTHUMG00000164045 +56893 UBQLN4 MIM:605440|HGNC:HGNC:1237|Ensembl:ENSG00000160803|Vega:OTTHUMG00000017461 +56894 AGPAT3 MIM:614794|HGNC:HGNC:326|Ensembl:ENSG00000160216|Vega:OTTHUMG00000086892 +56895 AGPAT4 MIM:614795|HGNC:HGNC:20885|Ensembl:ENSG00000026652|Vega:OTTHUMG00000015966 +56896 DPYSL5 MIM:608383|HGNC:HGNC:20637|Ensembl:ENSG00000157851|Vega:OTTHUMG00000097071 +56897 WRNIP1 MIM:608196|HGNC:HGNC:20876|Ensembl:ENSG00000124535|Vega:OTTHUMG00000014126 +56898 BDH2 HGNC:HGNC:32389|Ensembl:ENSG00000164039|Vega:OTTHUMG00000074039 +56899 ANKS1B MIM:607815|HGNC:HGNC:24600|Ensembl:ENSG00000185046|Vega:OTTHUMG00000170308 +56900 TMEM167B HGNC:HGNC:30187|Ensembl:ENSG00000215717|Vega:OTTHUMG00000042364 +56901 NDUFA4L2 HGNC:HGNC:29836|Ensembl:ENSG00000185633|Vega:OTTHUMG00000171275 +56902 PNO1 HGNC:HGNC:32790|Ensembl:ENSG00000115946|Vega:OTTHUMG00000129563 +56903 PAPOLB MIM:607436|HGNC:HGNC:15970|Ensembl:ENSG00000218823|Vega:OTTHUMG00000151759 +56904 SH3GLB2 MIM:609288|HGNC:HGNC:10834|Ensembl:ENSG00000148341|Vega:OTTHUMG00000020769 +56905 C15orf39 HGNC:HGNC:24497|Ensembl:ENSG00000167173|Vega:OTTHUMG00000142820 +56906 THAP10 MIM:612538|HGNC:HGNC:23193|Ensembl:ENSG00000129028|Vega:OTTHUMG00000133388 +56907 SPIRE1 MIM:609216|HGNC:HGNC:30622|Ensembl:ENSG00000134278|Vega:OTTHUMG00000153940 +56910 STARD7 MIM:616712|HGNC:HGNC:18063|Ensembl:ENSG00000084090|Vega:OTTHUMG00000130457 +56911 MAP3K7CL MIM:611110|HGNC:HGNC:16457|Ensembl:ENSG00000156265|Vega:OTTHUMG00000078806 +56912 IFT46 HGNC:HGNC:26146|Ensembl:ENSG00000118096|Vega:OTTHUMG00000166408 +56913 C1GALT1 MIM:610555|HGNC:HGNC:24337|Ensembl:ENSG00000106392|Vega:OTTHUMG00000151912 +56914 OTOR MIM:606067|HGNC:HGNC:8517|Ensembl:ENSG00000125879|Vega:OTTHUMG00000031931 +56915 EXOSC5 MIM:606492|HGNC:HGNC:24662|Ensembl:ENSG00000077348|Vega:OTTHUMG00000182759 +56916 SMARCAD1 MIM:612761|HGNC:HGNC:18398|Ensembl:ENSG00000163104|Vega:OTTHUMG00000130971 +56917 MEIS3 HGNC:HGNC:29537|Ensembl:ENSG00000105419|Vega:OTTHUMG00000172280 +56918 C2orf83 HGNC:HGNC:25344|Ensembl:ENSG00000042304|Vega:OTTHUMG00000153550 +56919 DHX33 MIM:614405|HGNC:HGNC:16718|Ensembl:ENSG00000005100|Vega:OTTHUMG00000102041 +56920 SEMA3G HGNC:HGNC:30400|Ensembl:ENSG00000010319|Vega:OTTHUMG00000158570 +56922 MCCC1 MIM:609010|HGNC:HGNC:6936|Ensembl:ENSG00000078070|Vega:OTTHUMG00000158355 +56923 NMUR2 MIM:605108|HGNC:HGNC:16454|Ensembl:ENSG00000132911|Vega:OTTHUMG00000130131 +56924 PAK6 MIM:608110|HGNC:HGNC:16061|Ensembl:ENSG00000137843|Vega:OTTHUMG00000129921 +56925 LXN MIM:609305|HGNC:HGNC:13347|Ensembl:ENSG00000079257|Vega:OTTHUMG00000158807 +56926 NCLN MIM:609156|HGNC:HGNC:26923|Ensembl:ENSG00000125912|Vega:OTTHUMG00000180687 +56927 GPR108 HGNC:HGNC:17829|Ensembl:ENSG00000125734|Vega:OTTHUMG00000170129 +56928 SPPL2B MIM:608239|HGNC:HGNC:30627|Ensembl:ENSG00000005206|Vega:OTTHUMG00000180443 +56929 FEM1C MIM:608767|HGNC:HGNC:16933|Ensembl:ENSG00000145780|Vega:OTTHUMG00000128895 +56931 DUS3L HGNC:HGNC:26920|Ensembl:ENSG00000141994|Vega:OTTHUMG00000162311 +56934 CA10 MIM:604642|HGNC:HGNC:1369|Ensembl:ENSG00000154975|Vega:OTTHUMG00000177544 +56935 SMCO4 MIM:609477|HGNC:HGNC:24810|Ensembl:ENSG00000166002|Vega:OTTHUMG00000167442 +56936 CCDC177 HGNC:HGNC:23243|Ensembl:ENSG00000267909|Vega:OTTHUMG00000187379 +56937 PMEPA1 MIM:606564|HGNC:HGNC:14107|Ensembl:ENSG00000124225|Vega:OTTHUMG00000032831 +56938 ARNTL2 MIM:614517|HGNC:HGNC:18984|Ensembl:ENSG00000029153|Vega:OTTHUMG00000169257 +56940 DUSP22 MIM:616778|HGNC:HGNC:16077|Ensembl:ENSG00000112679|Vega:OTTHUMG00000014113 +56941 HMCES HGNC:HGNC:24446|Ensembl:ENSG00000183624|Vega:OTTHUMG00000159452 +56942 CMC2 HGNC:HGNC:24447|Ensembl:ENSG00000103121|Vega:OTTHUMG00000137625 +56943 ENY2 HGNC:HGNC:24449|Ensembl:ENSG00000120533|Vega:OTTHUMG00000164933 +56944 OLFML3 MIM:610088|HGNC:HGNC:24956|Ensembl:ENSG00000116774|Vega:OTTHUMG00000011980 +56945 MRPS22 MIM:605810|HGNC:HGNC:14508|Ensembl:ENSG00000175110|Vega:OTTHUMG00000159910 +56946 EMSY MIM:608574|HGNC:HGNC:18071|Ensembl:ENSG00000158636|Vega:OTTHUMG00000165282 +56947 MFF MIM:614785|HGNC:HGNC:24858|Ensembl:ENSG00000168958|Vega:OTTHUMG00000133180 +56948 SDR39U1 MIM:616162|HGNC:HGNC:20275|Ensembl:ENSG00000100445|Vega:OTTHUMG00000171316 +56949 XAB2 MIM:610850|HGNC:HGNC:14089|Ensembl:ENSG00000076924|Vega:OTTHUMG00000182404 +56950 SMYD2 MIM:610663|HGNC:HGNC:20982|Ensembl:ENSG00000143499|Vega:OTTHUMG00000037066 +56951 C5orf15 HGNC:HGNC:20656|Ensembl:ENSG00000113583|Vega:OTTHUMG00000129125 +56952 PRTFDC1 MIM:610751|HGNC:HGNC:23333|Ensembl:ENSG00000099256|Vega:OTTHUMG00000017829 +56953 NT5M MIM:605292|HGNC:HGNC:15769|Ensembl:ENSG00000205309|Vega:OTTHUMG00000059277 +56954 NIT2 MIM:616769|HGNC:HGNC:29878|Ensembl:ENSG00000114021|Vega:OTTHUMG00000159066 +56955 MEPE MIM:605912|HGNC:HGNC:13361|Ensembl:ENSG00000152595|Vega:OTTHUMG00000130592 +56956 LHX9 MIM:606066|HGNC:HGNC:14222|Ensembl:ENSG00000143355|Vega:OTTHUMG00000035656 +56957 OTUD7B MIM:611748|HGNC:HGNC:16683|Ensembl:ENSG00000264522|Vega:OTTHUMG00000012291 +56961 SHD MIM:610481|HGNC:HGNC:30633|Ensembl:ENSG00000105251|Vega:OTTHUMG00000181879 +56963 RGMA MIM:607362|HGNC:HGNC:30308|Ensembl:ENSG00000182175|Vega:OTTHUMG00000171781 +56964 WDR93 HGNC:HGNC:26924|Ensembl:ENSG00000140527|Vega:OTTHUMG00000172007 +56965 PARP6 HGNC:HGNC:26921|Ensembl:ENSG00000137817|Vega:OTTHUMG00000133443 +56967 C14orf132 HGNC:HGNC:20346|Ensembl:ENSG00000227051|Vega:OTTHUMG00000171393 +56969 RPL23AP32 HGNC:HGNC:25345 +56970 ATXN7L3 HGNC:HGNC:25416|Ensembl:ENSG00000087152|Vega:OTTHUMG00000181812 +56971 CEACAM19 MIM:606691|HGNC:HGNC:31951|Ensembl:ENSG00000186567|Vega:OTTHUMG00000151528 +56975 FAM20C MIM:611061|HGNC:HGNC:22140|Ensembl:ENSG00000177706|Vega:OTTHUMG00000151401 +56977 STOX2 MIM:617359|HGNC:HGNC:25450|Ensembl:ENSG00000173320|Vega:OTTHUMG00000160618 +56978 PRDM8 MIM:616639|HGNC:HGNC:13993|Ensembl:ENSG00000152784|Vega:OTTHUMG00000160885 +56979 PRDM9 MIM:609760|HGNC:HGNC:13994|Ensembl:ENSG00000164256|Vega:OTTHUMG00000161918 +56980 PRDM10 HGNC:HGNC:13995|Ensembl:ENSG00000170325|Vega:OTTHUMG00000165762 +56981 PRDM11 MIM:616347|HGNC:HGNC:13996|Ensembl:ENSG00000019485|Vega:OTTHUMG00000166478 +56983 POGLUT1 MIM:615618|HGNC:HGNC:22954|Ensembl:ENSG00000163389|Vega:OTTHUMG00000159379 +56984 PSMG2 MIM:609702|HGNC:HGNC:24929|Ensembl:ENSG00000128789|Vega:OTTHUMG00000131703 +56985 ADPRM HGNC:HGNC:30925|Ensembl:ENSG00000170222|Vega:OTTHUMG00000130366 +56986 DTWD1 HGNC:HGNC:30926|Ensembl:ENSG00000104047|Vega:OTTHUMG00000131567 +56987 BBX HGNC:HGNC:14422|Ensembl:ENSG00000114439|Vega:OTTHUMG00000150360 +56990 CDC42SE2 HGNC:HGNC:18547|Ensembl:ENSG00000158985|Vega:OTTHUMG00000162692 +56992 KIF15 HGNC:HGNC:17273|Ensembl:ENSG00000163808|Vega:OTTHUMG00000156307 +56993 TOMM22 MIM:607046|HGNC:HGNC:18002|Ensembl:ENSG00000100216|Vega:OTTHUMG00000150991 +56994 CHPT1 MIM:616747|HGNC:HGNC:17852|Ensembl:ENSG00000111666|Vega:OTTHUMG00000170443 +56995 TULP4 HGNC:HGNC:15530|Ensembl:ENSG00000130338|Vega:OTTHUMG00000015910 +56996 SLC12A9 MIM:616861|HGNC:HGNC:17435|Ensembl:ENSG00000146828|Vega:OTTHUMG00000156045 +56997 COQ8A MIM:606980|HGNC:HGNC:16812|Ensembl:ENSG00000163050|Vega:OTTHUMG00000037621 +56998 CTNNBIP1 MIM:607758|HGNC:HGNC:16913|Ensembl:ENSG00000178585|Vega:OTTHUMG00000001796 +56999 ADAMTS9 MIM:605421|HGNC:HGNC:13202|Ensembl:ENSG00000163638|Vega:OTTHUMG00000158722 +57000 GSN-AS1 HGNC:HGNC:23372|Ensembl:ENSG00000235865 +57001 SDHAF3 MIM:615773|HGNC:HGNC:21752|Ensembl:ENSG00000196636|Vega:OTTHUMG00000154064 +57002 YAE1D1 HGNC:HGNC:24857|Ensembl:ENSG00000241127|Vega:OTTHUMG00000128689 +57003 CCDC47 HGNC:HGNC:24856|Ensembl:ENSG00000108588|Vega:OTTHUMG00000178933 +57004 UNGP1 HGNC:HGNC:18579 +57005 UNGP2 HGNC:HGNC:18580 +57007 ACKR3 MIM:610376|HGNC:HGNC:23692|Ensembl:ENSG00000144476|Vega:OTTHUMG00000133295 +57008 RLFP1 HGNC:HGNC:16738 +57009 PTS-P1 - +57010 CABP4 MIM:608965|HGNC:HGNC:1386|Ensembl:ENSG00000175544|Vega:OTTHUMG00000168033 +57016 AKR1B10 MIM:604707|HGNC:HGNC:382|Ensembl:ENSG00000198074|Vega:OTTHUMG00000155356 +57017 COQ9 MIM:612837|HGNC:HGNC:25302|Ensembl:ENSG00000088682|Vega:OTTHUMG00000176582 +57018 CCNL1 MIM:613384|HGNC:HGNC:20569|Ensembl:ENSG00000163660|Vega:OTTHUMG00000158713 +57019 CIAPIN1 MIM:608943|HGNC:HGNC:28050|Ensembl:ENSG00000005194|Vega:OTTHUMG00000133457 +57020 C16orf62 HGNC:HGNC:24641|Ensembl:ENSG00000103544|Vega:OTTHUMG00000167925 +57026 PDXP MIM:609246|HGNC:HGNC:30259|Ensembl:ENSG00000241360|Vega:OTTHUMG00000044618 +57030 SLC17A7 MIM:605208|HGNC:HGNC:16704|Ensembl:ENSG00000104888|Vega:OTTHUMG00000183166 +57035 RSRP1 HGNC:HGNC:25234|Ensembl:ENSG00000117616|Vega:OTTHUMG00000043611 +57037 ANKMY2 HGNC:HGNC:25370|Ensembl:ENSG00000106524|Vega:OTTHUMG00000090806 +57038 RARS2 MIM:611524|HGNC:HGNC:21406|Ensembl:ENSG00000146282|Vega:OTTHUMG00000015178 +57042 IBD7 MIM:605225|HGNC:HGNC:14242 +57044 IDDM18 MIM:605598|HGNC:HGNC:5372 +57045 TWSG1 MIM:605049|HGNC:HGNC:12429|Ensembl:ENSG00000128791|Vega:OTTHUMG00000131597 +57046 HRES2 - +57047 PLSCR2 MIM:607610|HGNC:HGNC:16494|Ensembl:ENSG00000163746|Vega:OTTHUMG00000159429 +57048 PLSCR3 MIM:607611|HGNC:HGNC:16495|Ensembl:ENSG00000187838|Vega:OTTHUMG00000178169 +57050 UTP3 MIM:611614|HGNC:HGNC:24477|Ensembl:ENSG00000132467|Vega:OTTHUMG00000129911 +57053 CHRNA10 MIM:606372|HGNC:HGNC:13800|Ensembl:ENSG00000129749|Vega:OTTHUMG00000011844 +57054 DAZ3 MIM:400027|HGNC:HGNC:15965|Ensembl:ENSG00000187191|Vega:OTTHUMG00000045099 +57055 DAZ2 MIM:400026|HGNC:HGNC:15964|Ensembl:ENSG00000205944|Vega:OTTHUMG00000044060 +57057 TBX20 MIM:606061|HGNC:HGNC:11598|Ensembl:ENSG00000164532|Vega:OTTHUMG00000099411 +57060 PCBP4 MIM:608503|HGNC:HGNC:8652|Ensembl:ENSG00000090097|Vega:OTTHUMG00000157366 +57061 HYMAI MIM:606546|HGNC:HGNC:5326|Ensembl:ENSG00000283122 +57062 DDX24 MIM:606181|HGNC:HGNC:13266|Ensembl:ENSG00000089737|Vega:OTTHUMG00000171301 +57082 KNL1 MIM:609173|HGNC:HGNC:24054|Ensembl:ENSG00000137812|Vega:OTTHUMG00000166532 +57084 SLC17A6 MIM:607563|HGNC:HGNC:16703|Ensembl:ENSG00000091664|Vega:OTTHUMG00000166063 +57085 AGTRAP MIM:608729|HGNC:HGNC:13539|Ensembl:ENSG00000177674|Vega:OTTHUMG00000002230 +57088 PLSCR4 MIM:607612|HGNC:HGNC:16497|Ensembl:ENSG00000114698|Vega:OTTHUMG00000159415 +57089 ENTPD7 MIM:616753|HGNC:HGNC:19745|Ensembl:ENSG00000198018|Vega:OTTHUMG00000018888 +57091 CASS4 HGNC:HGNC:15878|Ensembl:ENSG00000087589|Vega:OTTHUMG00000032788 +57092 PCNP MIM:615210|HGNC:HGNC:30023|Ensembl:ENSG00000081154|Vega:OTTHUMG00000159108 +57093 TRIM49 MIM:606124|HGNC:HGNC:13431|Ensembl:ENSG00000168930|Vega:OTTHUMG00000167634 +57094 CPA6 MIM:609562|HGNC:HGNC:17245|Ensembl:ENSG00000165078|Vega:OTTHUMG00000164575 +57095 PITHD1 HGNC:HGNC:25022|Ensembl:ENSG00000057757|Vega:OTTHUMG00000002960 +57096 RPGRIP1 MIM:605446|HGNC:HGNC:13436|Ensembl:ENSG00000092200|Vega:OTTHUMG00000170758 +57097 PARP11 MIM:616706|HGNC:HGNC:1186|Ensembl:ENSG00000111224|Vega:OTTHUMG00000156442 +57099 AVEN MIM:605265|HGNC:HGNC:13509|Ensembl:ENSG00000169857|Vega:OTTHUMG00000129371 +57101 ANO2 MIM:610109|HGNC:HGNC:1183|Ensembl:ENSG00000047617|Vega:OTTHUMG00000168264 +57102 C12orf4 MIM:616082|HGNC:HGNC:1184|Ensembl:ENSG00000047621|Vega:OTTHUMG00000168258 +57103 TIGAR MIM:610775|HGNC:HGNC:1185|Ensembl:ENSG00000078237|Vega:OTTHUMG00000168124 +57104 PNPLA2 MIM:609059|HGNC:HGNC:30802|Ensembl:ENSG00000177666|Vega:OTTHUMG00000133309 +57105 CYSLTR2 MIM:605666|HGNC:HGNC:18274|Ensembl:ENSG00000152207|Vega:OTTHUMG00000016906 +57106 NAT14 HGNC:HGNC:28918|Ensembl:ENSG00000090971|Vega:OTTHUMG00000180854 +57107 PDSS2 MIM:610564|HGNC:HGNC:23041|Ensembl:ENSG00000164494|Vega:OTTHUMG00000059359 +57108 SETD8P1 HGNC:HGNC:30088 +57109 REXO4 MIM:602930|HGNC:HGNC:12820|Ensembl:ENSG00000148300 +57110 HRASLS MIM:606487|HGNC:HGNC:14922|Ensembl:ENSG00000127252|Vega:OTTHUMG00000156104 +57111 RAB25 MIM:612942|HGNC:HGNC:18238|Ensembl:ENSG00000132698|Vega:OTTHUMG00000017457 +57113 TRPC7 HGNC:HGNC:20754|Ensembl:ENSG00000069018|Vega:OTTHUMG00000189265 +57115 PGLYRP4 MIM:608198|HGNC:HGNC:30015|Ensembl:ENSG00000163218|Vega:OTTHUMG00000037057 +57116 ZNF695 MIM:616348|HGNC:HGNC:30954|Ensembl:ENSG00000197472|Vega:OTTHUMG00000040707 +57117 INTS12 MIM:611355|HGNC:HGNC:25067|Ensembl:ENSG00000138785|Vega:OTTHUMG00000131215 +57118 CAMK1D MIM:607957|HGNC:HGNC:19341|Ensembl:ENSG00000183049|Vega:OTTHUMG00000017683 +57119 EPPIN MIM:609031|HGNC:HGNC:15932|Ensembl:ENSG00000101448|Vega:OTTHUMG00000032588 +57120 GOPC MIM:606845|HGNC:HGNC:17643|Ensembl:ENSG00000047932|Vega:OTTHUMG00000015457 +57121 LPAR5 MIM:606926|HGNC:HGNC:13307|Ensembl:ENSG00000184574|Vega:OTTHUMG00000168713 +57122 NUP107 MIM:607617|HGNC:HGNC:29914|Ensembl:ENSG00000111581|Vega:OTTHUMG00000169265 +57124 CD248 MIM:606064|HGNC:HGNC:18219|Ensembl:ENSG00000174807|Vega:OTTHUMG00000167073 +57125 PLXDC1 MIM:606826|HGNC:HGNC:20945|Ensembl:ENSG00000161381|Vega:OTTHUMG00000133183 +57126 CD177 MIM:162860|HGNC:HGNC:30072|Ensembl:ENSG00000204936|Vega:OTTHUMG00000185320 +57127 RHBG MIM:607079|HGNC:HGNC:14572|Ensembl:ENSG00000132677|Vega:OTTHUMG00000024057 +57128 LYRM4 MIM:613311|HGNC:HGNC:21365|Ensembl:ENSG00000214113|Vega:OTTHUMG00000014173 +57129 MRPL47 MIM:611852|HGNC:HGNC:16652|Ensembl:ENSG00000136522|Vega:OTTHUMG00000157784 +57130 ATP13A1 HGNC:HGNC:24215|Ensembl:ENSG00000105726|Vega:OTTHUMG00000153016 +57132 CHMP1B MIM:606486|HGNC:HGNC:24287|Ensembl:ENSG00000255112|Vega:OTTHUMG00000165820 +57134 MAN1C1 MIM:616772|HGNC:HGNC:19080|Ensembl:ENSG00000117643|Vega:OTTHUMG00000004417 +57135 DAZ4 HGNC:HGNC:15966|Ensembl:ENSG00000205916|Vega:OTTHUMG00000045100 +57136 APMAP MIM:615884|HGNC:HGNC:13238|Ensembl:ENSG00000101474|Vega:OTTHUMG00000032107 +57139 RGL3 MIM:616743|HGNC:HGNC:30282|Ensembl:ENSG00000205517|Vega:OTTHUMG00000172898 +57140 RNPEPL1 MIM:605287|HGNC:HGNC:10079|Ensembl:ENSG00000142327 +57142 RTN4 MIM:604475|HGNC:HGNC:14085|Ensembl:ENSG00000115310|Vega:OTTHUMG00000129337 +57143 ADCK1 HGNC:HGNC:19038|Ensembl:ENSG00000063761|Vega:OTTHUMG00000171520 +57144 PAK5 MIM:608038|HGNC:HGNC:15916|Ensembl:ENSG00000101349|Vega:OTTHUMG00000031857 +57146 TMEM159 MIM:611304|HGNC:HGNC:30136|Ensembl:ENSG00000011638|Vega:OTTHUMG00000131559 +57147 SCYL3 MIM:608192|HGNC:HGNC:19285|Ensembl:ENSG00000000457|Vega:OTTHUMG00000035941 +57148 RALGAPB HGNC:HGNC:29221|Ensembl:ENSG00000170471|Vega:OTTHUMG00000140270 +57149 LYRM1 MIM:614709|HGNC:HGNC:25074|Ensembl:ENSG00000102897|Vega:OTTHUMG00000131554 +57150 SMIM8 HGNC:HGNC:21401|Ensembl:ENSG00000111850|Vega:OTTHUMG00000015168 +57151 LYZL6 MIM:612751|HGNC:HGNC:29614|Ensembl:ENSG00000275722|Vega:OTTHUMG00000188400 +57152 SLURP1 MIM:606119|HGNC:HGNC:18746|Ensembl:ENSG00000126233|Vega:OTTHUMG00000164685 +57153 SLC44A2 MIM:606106|HGNC:HGNC:17292|Ensembl:ENSG00000129353|Vega:OTTHUMG00000180585 +57154 SMURF1 MIM:605568|HGNC:HGNC:16807|Ensembl:ENSG00000198742|Vega:OTTHUMG00000150272 +57156 TMEM63C HGNC:HGNC:23787|Ensembl:ENSG00000165548|Vega:OTTHUMG00000171557 +57157 PHTF2 MIM:616785|HGNC:HGNC:13411|Ensembl:ENSG00000006576|Vega:OTTHUMG00000155557 +57158 JPH2 MIM:605267|HGNC:HGNC:14202|Ensembl:ENSG00000149596|Vega:OTTHUMG00000033037 +57159 TRIM54 MIM:606474|HGNC:HGNC:16008|Ensembl:ENSG00000138100|Vega:OTTHUMG00000097078 +57160 TBX23P HGNC:HGNC:11601 +57161 PELI2 MIM:614798|HGNC:HGNC:8828|Ensembl:ENSG00000139946|Vega:OTTHUMG00000152336 +57162 PELI1 MIM:614797|HGNC:HGNC:8827|Ensembl:ENSG00000197329|Vega:OTTHUMG00000129511 +57165 GJC2 MIM:608803|HGNC:HGNC:17494|Ensembl:ENSG00000198835|Vega:OTTHUMG00000039771 +57167 SALL4 MIM:607343|HGNC:HGNC:15924|Ensembl:ENSG00000101115|Vega:OTTHUMG00000032752 +57168 ASPHD2 HGNC:HGNC:30437|Ensembl:ENSG00000128203|Vega:OTTHUMG00000150884 +57169 ZNFX1 HGNC:HGNC:29271|Ensembl:ENSG00000124201|Vega:OTTHUMG00000032696 +57171 DOLPP1 MIM:614516|HGNC:HGNC:29565|Ensembl:ENSG00000167130|Vega:OTTHUMG00000020771 +57172 CAMK1G MIM:614994|HGNC:HGNC:14585|Ensembl:ENSG00000008118|Vega:OTTHUMG00000036361 +57175 CORO1B MIM:609849|HGNC:HGNC:2253|Ensembl:ENSG00000172725|Vega:OTTHUMG00000167775 +57176 VARS2 MIM:612802|HGNC:HGNC:21642|Ensembl:ENSG00000137411|Vega:OTTHUMG00000031263 +57178 ZMIZ1 MIM:607159|HGNC:HGNC:16493|Ensembl:ENSG00000108175|Vega:OTTHUMG00000018560 +57179 KIAA1191 HGNC:HGNC:29209|Ensembl:ENSG00000122203|Vega:OTTHUMG00000130656 +57180 ACTR3B HGNC:HGNC:17256|Ensembl:ENSG00000133627|Vega:OTTHUMG00000151463 +57181 SLC39A10 MIM:608733|HGNC:HGNC:20861|Ensembl:ENSG00000196950|Vega:OTTHUMG00000154380 +57182 ANKRD50 HGNC:HGNC:29223|Ensembl:ENSG00000151458|Vega:OTTHUMG00000161398 +57184 FAM219B HGNC:HGNC:24695|Ensembl:ENSG00000178761|Vega:OTTHUMG00000172715 +57185 NIPAL3 HGNC:HGNC:25233|Ensembl:ENSG00000001461|Vega:OTTHUMG00000003299 +57186 RALGAPA2 HGNC:HGNC:16207|Ensembl:ENSG00000188559|Vega:OTTHUMG00000032010 +57187 THOC2 MIM:300395|HGNC:HGNC:19073|Ensembl:ENSG00000125676|Vega:OTTHUMG00000022334 +57188 ADAMTSL3 MIM:609199|HGNC:HGNC:14633|Ensembl:ENSG00000156218|Vega:OTTHUMG00000147363 +57189 KIAA1147 HGNC:HGNC:29472|Ensembl:ENSG00000257093|Vega:OTTHUMG00000157539 +57190 SELENON MIM:606210|HGNC:HGNC:15999|Ensembl:ENSG00000162430|Vega:OTTHUMG00000007375 +57191 VN1R1 MIM:605234|HGNC:HGNC:13548|Ensembl:ENSG00000178201|Vega:OTTHUMG00000183400 +57192 MCOLN1 MIM:605248|HGNC:HGNC:13356|Ensembl:ENSG00000090674|Vega:OTTHUMG00000182046 +57194 ATP10A MIM:605855|HGNC:HGNC:13542|Ensembl:ENSG00000206190|Vega:OTTHUMG00000171703 +57198 ATP8B2 MIM:605867|HGNC:HGNC:13534|Ensembl:ENSG00000143515|Vega:OTTHUMG00000035979 +57205 ATP10D HGNC:HGNC:13549|Ensembl:ENSG00000145246|Vega:OTTHUMG00000160784 +57209 ZNF248 HGNC:HGNC:13041|Ensembl:ENSG00000198105|Vega:OTTHUMG00000017980 +57210 SLC45A4 HGNC:HGNC:29196|Ensembl:ENSG00000022567|Vega:OTTHUMG00000164393 +57211 ADGRG6 MIM:612243|HGNC:HGNC:13841|Ensembl:ENSG00000112414|Vega:OTTHUMG00000015709 +57212 TP73-AS1 HGNC:HGNC:29052|Ensembl:ENSG00000227372 +57213 SPRYD7 MIM:607866|HGNC:HGNC:14297|Ensembl:ENSG00000123178|Vega:OTTHUMG00000016924 +57214 CEMIP MIM:608366|HGNC:HGNC:29213|Ensembl:ENSG00000103888|Vega:OTTHUMG00000144184 +57215 THAP11 MIM:609119|HGNC:HGNC:23194|Ensembl:ENSG00000168286|Vega:OTTHUMG00000137546 +57216 VANGL2 MIM:600533|HGNC:HGNC:15511|Ensembl:ENSG00000162738|Vega:OTTHUMG00000033122 +57217 TTC7A MIM:609332|HGNC:HGNC:19750|Ensembl:ENSG00000068724|Vega:OTTHUMG00000153121 +57221 ARFGEF3 MIM:617411|HGNC:HGNC:21213|Ensembl:ENSG00000112379|Vega:OTTHUMG00000015670 +57222 ERGIC1 HGNC:HGNC:29205|Ensembl:ENSG00000113719|Vega:OTTHUMG00000130520 +57223 PPP4R3B MIM:610352|HGNC:HGNC:29267|Ensembl:ENSG00000275052|Vega:OTTHUMG00000129336 +57224 NHSL1 HGNC:HGNC:21021|Ensembl:ENSG00000135540|Vega:OTTHUMG00000016321 +57226 LYRM2 HGNC:HGNC:25229|Ensembl:ENSG00000083099|Vega:OTTHUMG00000015203 +57228 SMAGP HGNC:HGNC:26918|Ensembl:ENSG00000170545|Vega:OTTHUMG00000185196 +57231 SNX14 MIM:616105|HGNC:HGNC:14977|Ensembl:ENSG00000135317|Vega:OTTHUMG00000015140 +57232 ZNF630 MIM:300819|HGNC:HGNC:28855|Ensembl:ENSG00000221994|Vega:OTTHUMG00000021463 +57234 LINC00869 HGNC:HGNC:29050|Ensembl:ENSG00000277147 +57282 SLC4A10 MIM:605556|HGNC:HGNC:13811|Ensembl:ENSG00000144290|Vega:OTTHUMG00000153938 +57289 IGHV7-4-1 HGNC:HGNC:5665|IMGT/GENE-DB:IGHV7-4-1 +57290 IGHV3-30-3 HGNC:HGNC:5593|IMGT/GENE-DB:IGHV3-30-3 +57291 DANCR MIM:614625|HGNC:HGNC:28964|Ensembl:ENSG00000226950 +57292 KIR2DL5A MIM:605305|HGNC:HGNC:16345 +57306 CUP2Q35 MIM:185900 +57309 SPG14 MIM:605229|HGNC:HGNC:13730 +57324 TSE2 MIM:601136 +57325 KAT14 MIM:617501|HGNC:HGNC:15904|Ensembl:ENSG00000149474|Vega:OTTHUMG00000031962 +57326 PBXIP1 HGNC:HGNC:21199|Ensembl:ENSG00000163346|Vega:OTTHUMG00000037369 +57332 CBX8 MIM:617354|HGNC:HGNC:15962|Ensembl:ENSG00000141570|Vega:OTTHUMG00000150416 +57333 RCN3 HGNC:HGNC:21145|Ensembl:ENSG00000142552|Vega:OTTHUMG00000183154 +57335 ZNF286A HGNC:HGNC:13501|Ensembl:ENSG00000187607|Ensembl:ENSG00000255104|Vega:OTTHUMG00000059066|Vega:OTTHUMG00000166448 +57336 ZNF287 HGNC:HGNC:13502|Ensembl:ENSG00000141040|Vega:OTTHUMG00000058993 +57337 SENP7 MIM:612846|HGNC:HGNC:30402|Ensembl:ENSG00000138468|Vega:OTTHUMG00000149927 +57338 JPH3 MIM:605268|HGNC:HGNC:14203|Ensembl:ENSG00000154118|Vega:OTTHUMG00000137656 +57343 ZNF304 MIM:613840|HGNC:HGNC:13505|Ensembl:ENSG00000131845|Vega:OTTHUMG00000183245 +57348 TTYH1 MIM:605784|HGNC:HGNC:13476|Ensembl:ENSG00000167614|Vega:OTTHUMG00000065544 +57369 GJD2 MIM:607058|HGNC:HGNC:19154|Ensembl:ENSG00000159248|Vega:OTTHUMG00000129674 +57379 AICDA MIM:605257|HGNC:HGNC:13203|Ensembl:ENSG00000111732|Vega:OTTHUMG00000168676 +57380 MRS2 HGNC:HGNC:13785|Ensembl:ENSG00000124532|Vega:OTTHUMG00000014355 +57381 RHOJ MIM:607653|HGNC:HGNC:688|Ensembl:ENSG00000126785|Vega:OTTHUMG00000140342 +57393 TMEM27 MIM:300631|HGNC:HGNC:29437|Ensembl:ENSG00000147003|Vega:OTTHUMG00000021181 +57396 CLK4 MIM:607969|HGNC:HGNC:13659|Ensembl:ENSG00000113240|Vega:OTTHUMG00000130893 +57402 S100A14 MIM:607986|HGNC:HGNC:18901|Ensembl:ENSG00000189334|Vega:OTTHUMG00000035030 +57403 RAB22A MIM:612966|HGNC:HGNC:9764|Ensembl:ENSG00000124209|Vega:OTTHUMG00000032844 +57404 CYP20A1 HGNC:HGNC:20576|Ensembl:ENSG00000119004|Vega:OTTHUMG00000132854 +57405 SPC25 MIM:609395|HGNC:HGNC:24031|Ensembl:ENSG00000152253|Vega:OTTHUMG00000132181 +57406 ABHD6 MIM:616966|HGNC:HGNC:21398|Ensembl:ENSG00000163686|Vega:OTTHUMG00000159150 +57407 NMRAL1 HGNC:HGNC:24987|Ensembl:ENSG00000153406|Vega:OTTHUMG00000129468 +57408 LRTM1 HGNC:HGNC:25023|Ensembl:ENSG00000144771|Vega:OTTHUMG00000158578 +57409 MIF4GD MIM:612072|HGNC:HGNC:24030|Ensembl:ENSG00000125457|Vega:OTTHUMG00000179485 +57410 SCYL1 MIM:607982|HGNC:HGNC:14372|Ensembl:ENSG00000142186|Vega:OTTHUMG00000166325 +57412 AS3MT MIM:611806|HGNC:HGNC:17452|Ensembl:ENSG00000214435|Vega:OTTHUMG00000018972 +57413 TMIGD3 HGNC:HGNC:51375|Ensembl:ENSG00000121933|Vega:OTTHUMG00000190810 +57414 RHBDD2 MIM:615203|HGNC:HGNC:23082|Ensembl:ENSG00000005486|Vega:OTTHUMG00000156435 +57415 C3orf14 HGNC:HGNC:25024|Ensembl:ENSG00000114405|Vega:OTTHUMG00000158704 +57418 WDR18 HGNC:HGNC:17956|Ensembl:ENSG00000065268|Vega:OTTHUMG00000181903 +57419 SLC24A3 MIM:609839|HGNC:HGNC:10977|Ensembl:ENSG00000185052|Vega:OTTHUMG00000031993 +57446 NDRG3 MIM:605273|HGNC:HGNC:14462|Ensembl:ENSG00000101079|Vega:OTTHUMG00000032398 +57447 NDRG2 MIM:605272|HGNC:HGNC:14460|Ensembl:ENSG00000165795|Vega:OTTHUMG00000029619 +57448 BIRC6 MIM:605638|HGNC:HGNC:13516|Ensembl:ENSG00000115760|Vega:OTTHUMG00000150528 +57449 PLEKHG5 MIM:611101|HGNC:HGNC:29105|Ensembl:ENSG00000171680|Vega:OTTHUMG00000000905 +57451 TENM2 MIM:610119|HGNC:HGNC:29943|Ensembl:ENSG00000145934|Vega:OTTHUMG00000162928 +57452 GALNT16 MIM:615132|HGNC:HGNC:23233|Ensembl:ENSG00000100626|Vega:OTTHUMG00000171231 +57453 DSCAML1 MIM:611782|HGNC:HGNC:14656|Ensembl:ENSG00000177103|Vega:OTTHUMG00000167071 +57455 REXO1 MIM:609614|HGNC:HGNC:24616|Ensembl:ENSG00000079313|Vega:OTTHUMG00000179991 +57456 KIAA1143 HGNC:HGNC:29198|Ensembl:ENSG00000163807|Vega:OTTHUMG00000133088 +57458 TMCC3 MIM:617459|HGNC:HGNC:29199|Ensembl:ENSG00000057704|Vega:OTTHUMG00000170225 +57459 GATAD2B MIM:614998|HGNC:HGNC:30778|Ensembl:ENSG00000143614|Vega:OTTHUMG00000037162 +57460 PPM1H MIM:616016|HGNC:HGNC:18583|Ensembl:ENSG00000111110|Vega:OTTHUMG00000169990 +57461 ISY1 MIM:612764|HGNC:HGNC:29201|Ensembl:ENSG00000240682|Vega:OTTHUMG00000137365 +57462 KIAA1161 HGNC:HGNC:19918|Ensembl:ENSG00000164976|Vega:OTTHUMG00000019816 +57463 AMIGO1 MIM:615689|HGNC:HGNC:20824|Ensembl:ENSG00000181754|Vega:OTTHUMG00000011653 +57464 STRIP2 HGNC:HGNC:22209|Ensembl:ENSG00000128578|Vega:OTTHUMG00000157695 +57465 TBC1D24 MIM:613577|HGNC:HGNC:29203|Ensembl:ENSG00000162065|Vega:OTTHUMG00000177150 +57466 SCAF4 MIM:616023|HGNC:HGNC:19304|Ensembl:ENSG00000156304|Vega:OTTHUMG00000084903 +57467 HHATL MIM:608116|HGNC:HGNC:13242|Ensembl:ENSG00000010282|Vega:OTTHUMG00000133043 +57468 SLC12A5 MIM:606726|HGNC:HGNC:13818|Ensembl:ENSG00000124140|Vega:OTTHUMG00000032638 +57469 PNMA8B HGNC:HGNC:29206|Ensembl:ENSG00000204851|Vega:OTTHUMG00000183426 +57470 LRRC47 HGNC:HGNC:29207|Ensembl:ENSG00000130764|Vega:OTTHUMG00000003506 +57471 ERMN MIM:610072|HGNC:HGNC:29208|Ensembl:ENSG00000136541|Vega:OTTHUMG00000153843 +57472 CNOT6 MIM:608951|HGNC:HGNC:14099|Ensembl:ENSG00000113300|Vega:OTTHUMG00000130935 +57473 ZNF512B HGNC:HGNC:29212|Ensembl:ENSG00000196700|Vega:OTTHUMG00000033008 +57474 ZNF490 HGNC:HGNC:23705|Ensembl:ENSG00000188033|Vega:OTTHUMG00000156398 +57475 PLEKHH1 HGNC:HGNC:17733|Ensembl:ENSG00000054690|Vega:OTTHUMG00000171272 +57476 GRAMD1B HGNC:HGNC:29214|Ensembl:ENSG00000023171|Vega:OTTHUMG00000166004 +57477 SHROOM4 MIM:300579|HGNC:HGNC:29215|Ensembl:ENSG00000158352|Vega:OTTHUMG00000021521 +57478 USP31 HGNC:HGNC:20060|Ensembl:ENSG00000103404|Vega:OTTHUMG00000094793 +57479 PRR12 MIM:616633|HGNC:HGNC:29217|Ensembl:ENSG00000126464|Vega:OTTHUMG00000183275 +57480 PLEKHG1 HGNC:HGNC:20884|Ensembl:ENSG00000120278|Vega:OTTHUMG00000015824 +57481 KIAA1210 MIM:300995|HGNC:HGNC:29218|Ensembl:ENSG00000250423|Vega:OTTHUMG00000162980 +57482 KIAA1211 HGNC:HGNC:29219|Ensembl:ENSG00000109265|Vega:OTTHUMG00000160749 +57484 RNF150 HGNC:HGNC:23138|Ensembl:ENSG00000170153|Vega:OTTHUMG00000161380 +57486 NLN MIM:611530|HGNC:HGNC:16058|Ensembl:ENSG00000123213|Vega:OTTHUMG00000097803 +57488 ESYT2 MIM:616691|HGNC:HGNC:22211|Ensembl:ENSG00000117868|Vega:OTTHUMG00000151436 +57489 ODF2L HGNC:HGNC:29225|Ensembl:ENSG00000122417|Vega:OTTHUMG00000010080 +57491 AHRR MIM:606517|HGNC:HGNC:346|Ensembl:ENSG00000063438|Vega:OTTHUMG00000162171 +57492 ARID1B MIM:614556|HGNC:HGNC:18040|Ensembl:ENSG00000049618|Vega:OTTHUMG00000015890 +57493 HEG1 MIM:614182|HGNC:HGNC:29227|Ensembl:ENSG00000173706|Vega:OTTHUMG00000159486 +57494 RIMKLB MIM:614054|HGNC:HGNC:29228|Ensembl:ENSG00000166532|Vega:OTTHUMG00000168197 +57495 NWD2 HGNC:HGNC:29229|Ensembl:ENSG00000174145|Vega:OTTHUMG00000157134 +57496 MKL2 MIM:609463|HGNC:HGNC:29819|Ensembl:ENSG00000186260|Vega:OTTHUMG00000177379 +57497 LRFN2 MIM:612808|HGNC:HGNC:21226|Ensembl:ENSG00000156564|Vega:OTTHUMG00000014662 +57498 KIDINS220 MIM:615759|HGNC:HGNC:29508|Ensembl:ENSG00000134313|Vega:OTTHUMG00000151658 +57501 KIAA1257 HGNC:HGNC:29231|Ensembl:ENSG00000114656|Ensembl:ENSG00000187695|Vega:OTTHUMG00000159946|Vega:OTTHUMG00000162589 +57502 NLGN4X MIM:300427|HGNC:HGNC:14287|Ensembl:ENSG00000146938|Vega:OTTHUMG00000021093 +57504 MTA3 MIM:609050|HGNC:HGNC:23784|Ensembl:ENSG00000057935|Vega:OTTHUMG00000150452 +57505 AARS2 MIM:612035|HGNC:HGNC:21022|Ensembl:ENSG00000124608|Vega:OTTHUMG00000014766 +57506 MAVS MIM:609676|HGNC:HGNC:29233|Ensembl:ENSG00000088888|Vega:OTTHUMG00000031765 +57507 ZNF608 HGNC:HGNC:29238|Ensembl:ENSG00000168916|Vega:OTTHUMG00000162999 +57508 INTS2 MIM:611346|HGNC:HGNC:29241|Ensembl:ENSG00000108506|Vega:OTTHUMG00000179234 +57509 MTUS1 MIM:609589|HGNC:HGNC:29789|Ensembl:ENSG00000129422|Vega:OTTHUMG00000163756 +57510 XPO5 MIM:607845|HGNC:HGNC:17675|Ensembl:ENSG00000124571|Vega:OTTHUMG00000014742 +57511 COG6 MIM:606977|HGNC:HGNC:18621|Ensembl:ENSG00000133103|Vega:OTTHUMG00000016768 +57512 GPR158 MIM:614573|HGNC:HGNC:23689|Ensembl:ENSG00000151025|Vega:OTTHUMG00000017832 +57513 CASKIN2 MIM:612185|HGNC:HGNC:18200|Ensembl:ENSG00000177303|Vega:OTTHUMG00000179683 +57514 ARHGAP31 MIM:610911|HGNC:HGNC:29216|Ensembl:ENSG00000031081|Vega:OTTHUMG00000159362 +57515 SERINC1 MIM:614548|HGNC:HGNC:13464|Ensembl:ENSG00000111897|Vega:OTTHUMG00000015487 +57519 STARD9 MIM:614642|HGNC:HGNC:19162|Ensembl:ENSG00000159433|Vega:OTTHUMG00000175799 +57520 HECW2 MIM:617245|HGNC:HGNC:29853|Ensembl:ENSG00000138411|Vega:OTTHUMG00000154435 +57521 RPTOR MIM:607130|HGNC:HGNC:30287|Ensembl:ENSG00000141564|Vega:OTTHUMG00000177622 +57522 SRGAP1 MIM:606523|HGNC:HGNC:17382|Ensembl:ENSG00000196935|Vega:OTTHUMG00000168750 +57523 NYNRIN HGNC:HGNC:20165|Ensembl:ENSG00000205978|Vega:OTTHUMG00000171314 +57524 CASKIN1 MIM:612184|HGNC:HGNC:20879|Ensembl:ENSG00000167971|Vega:OTTHUMG00000177045 +57526 PCDH19 MIM:300460|HGNC:HGNC:14270|Ensembl:ENSG00000165194|Vega:OTTHUMG00000022000 +57528 KCTD16 MIM:613423|HGNC:HGNC:29244|Ensembl:ENSG00000183775|Vega:OTTHUMG00000163172 +57529 RTL9 MIM:300965|HGNC:HGNC:29245|Ensembl:ENSG00000243978|Vega:OTTHUMG00000022196 +57530 CGN MIM:609473|HGNC:HGNC:17429|Ensembl:ENSG00000143375|Vega:OTTHUMG00000012497 +57531 HACE1 MIM:610876|HGNC:HGNC:21033|Ensembl:ENSG00000085382|Vega:OTTHUMG00000015287 +57532 NUFIP2 MIM:609356|HGNC:HGNC:17634|Ensembl:ENSG00000108256|Vega:OTTHUMG00000179547 +57533 TBC1D14 MIM:614855|HGNC:HGNC:29246|Ensembl:ENSG00000132405|Vega:OTTHUMG00000090493 +57534 MIB1 MIM:608677|HGNC:HGNC:21086|Ensembl:ENSG00000101752|Vega:OTTHUMG00000131753 +57535 KIAA1324 MIM:611298|HGNC:HGNC:29618|Ensembl:ENSG00000116299|Vega:OTTHUMG00000011725 +57536 KIAA1328 MIM:616480|HGNC:HGNC:29248|Ensembl:ENSG00000150477|Vega:OTTHUMG00000178087 +57537 SORCS2 MIM:606284|HGNC:HGNC:16698|Ensembl:ENSG00000184985|Vega:OTTHUMG00000159981 +57538 ALPK3 HGNC:HGNC:17574|Ensembl:ENSG00000136383|Vega:OTTHUMG00000148667 +57539 WDR35 MIM:613602|HGNC:HGNC:29250|Ensembl:ENSG00000118965|Vega:OTTHUMG00000090737 +57540 DISP3 MIM:611251|HGNC:HGNC:29251|Ensembl:ENSG00000204624|Vega:OTTHUMG00000002074 +57541 ZNF398 HGNC:HGNC:18373|Ensembl:ENSG00000197024|Vega:OTTHUMG00000158970 +57542 KLHL42 HGNC:HGNC:29252|Ensembl:ENSG00000087448|Vega:OTTHUMG00000169217 +57544 TXNDC16 MIM:616179|HGNC:HGNC:19965|Ensembl:ENSG00000087301|Vega:OTTHUMG00000171103 +57545 CC2D2A MIM:612013|HGNC:HGNC:29253|Ensembl:ENSG00000048342|Vega:OTTHUMG00000160255 +57546 PDP2 MIM:615499|HGNC:HGNC:30263|Ensembl:ENSG00000172840|Vega:OTTHUMG00000137512 +57547 ZNF624 HGNC:HGNC:29254|Ensembl:ENSG00000197566|Vega:OTTHUMG00000058996 +57549 IGSF9 MIM:609738|HGNC:HGNC:18132|Ensembl:ENSG00000085552|Vega:OTTHUMG00000022794 +57551 TAOK1 MIM:610266|HGNC:HGNC:29259|Ensembl:ENSG00000160551|Vega:OTTHUMG00000179718 +57552 NCEH1 MIM:613234|HGNC:HGNC:29260|Ensembl:ENSG00000144959|Vega:OTTHUMG00000156872 +57553 MICAL3 MIM:608882|HGNC:HGNC:24694|Ensembl:ENSG00000243156|Vega:OTTHUMG00000150067 +57554 LRRC7 MIM:614453|HGNC:HGNC:18531|Ensembl:ENSG00000033122|Vega:OTTHUMG00000059194 +57555 NLGN2 MIM:606479|HGNC:HGNC:14290|Ensembl:ENSG00000169992|Vega:OTTHUMG00000108138 +57556 SEMA6A MIM:605885|HGNC:HGNC:10738|Ensembl:ENSG00000092421|Vega:OTTHUMG00000162987 +57558 USP35 HGNC:HGNC:20061|Ensembl:ENSG00000118369|Vega:OTTHUMG00000166492 +57559 STAMBPL1 MIM:612352|HGNC:HGNC:24105|Ensembl:ENSG00000138134|Vega:OTTHUMG00000018702 +57560 IFT80 MIM:611177|HGNC:HGNC:29262|Ensembl:ENSG00000068885|Vega:OTTHUMG00000158953 +57561 ARRDC3 MIM:612464|HGNC:HGNC:29263|Ensembl:ENSG00000113369|Vega:OTTHUMG00000162616 +57562 CEP126 MIM:614634|HGNC:HGNC:29264|Ensembl:ENSG00000110318|Vega:OTTHUMG00000167319 +57563 KLHL8 MIM:611967|HGNC:HGNC:18644|Ensembl:ENSG00000145332|Vega:OTTHUMG00000130593 +57565 KLHL14 MIM:613772|HGNC:HGNC:29266|Ensembl:ENSG00000197705|Vega:OTTHUMG00000179819 +57567 ZNF319 HGNC:HGNC:13644|Ensembl:ENSG00000166188|Vega:OTTHUMG00000175512 +57568 SIPA1L2 MIM:611609|HGNC:HGNC:23800|Ensembl:ENSG00000116991|Vega:OTTHUMG00000037820 +57569 ARHGAP20 MIM:609568|HGNC:HGNC:18357|Ensembl:ENSG00000137727|Vega:OTTHUMG00000166590 +57570 TRMT5 MIM:611023|HGNC:HGNC:23141|Ensembl:ENSG00000126814|Vega:OTTHUMG00000171294 +57571 CARNS1 MIM:613368|HGNC:HGNC:29268|Ensembl:ENSG00000172508|Vega:OTTHUMG00000167672 +57572 DOCK6 MIM:614194|HGNC:HGNC:19189|Ensembl:ENSG00000130158|Vega:OTTHUMG00000180826 +57573 ZNF471 HGNC:HGNC:23226|Ensembl:ENSG00000196263|Vega:OTTHUMG00000181943 +57574 MARCH4 MIM:608208|HGNC:HGNC:29269|Ensembl:ENSG00000144583|Vega:OTTHUMG00000154824 +57575 PCDH10 MIM:608286|HGNC:HGNC:13404|Ensembl:ENSG00000138650|Vega:OTTHUMG00000161301 +57576 KIF17 MIM:605037|HGNC:HGNC:19167|Ensembl:ENSG00000117245|Vega:OTTHUMG00000002863 +57577 CCDC191 HGNC:HGNC:29272|Ensembl:ENSG00000163617|Vega:OTTHUMG00000159337 +57578 UNC79 MIM:616884|HGNC:HGNC:19966|Ensembl:ENSG00000133958|Vega:OTTHUMG00000029783 +57579 FAM135A HGNC:HGNC:21084|Ensembl:ENSG00000082269|Vega:OTTHUMG00000014991 +57580 PREX1 MIM:606905|HGNC:HGNC:32594|Ensembl:ENSG00000124126|Vega:OTTHUMG00000032685 +57582 KCNT1 MIM:608167|HGNC:HGNC:18865|Ensembl:ENSG00000107147|Vega:OTTHUMG00000020917 +57583 TMEM181 MIM:613209|HGNC:HGNC:20958|Ensembl:ENSG00000146433|Vega:OTTHUMG00000015913 +57584 ARHGAP21 MIM:609870|HGNC:HGNC:23725|Ensembl:ENSG00000107863|Vega:OTTHUMG00000017825 +57585 CRAMP1 HGNC:HGNC:14122|Ensembl:ENSG00000007545|Vega:OTTHUMG00000074087 +57586 SYT13 MIM:607716|HGNC:HGNC:14962|Ensembl:ENSG00000019505|Vega:OTTHUMG00000166504 +57587 CFAP97 MIM:616047|HGNC:HGNC:29276|Ensembl:ENSG00000164323|Vega:OTTHUMG00000160468 +57589 RIC1 MIM:610354|HGNC:HGNC:17686|Ensembl:ENSG00000107036|Vega:OTTHUMG00000019505 +57590 WDFY1 HGNC:HGNC:20451|Ensembl:ENSG00000085449|Vega:OTTHUMG00000153370 +57591 MKL1 MIM:606078|HGNC:HGNC:14334|Ensembl:ENSG00000196588|Vega:OTTHUMG00000151146 +57592 ZNF687 MIM:610568|HGNC:HGNC:29277|Ensembl:ENSG00000143373|Vega:OTTHUMG00000012347 +57593 EBF4 MIM:609935|HGNC:HGNC:29278|Ensembl:ENSG00000088881|Vega:OTTHUMG00000031709 +57594 HOMEZ MIM:608119|HGNC:HGNC:20164|Ensembl:ENSG00000215271|Vega:OTTHUMG00000172122 +57595 PDZD4 MIM:300634|HGNC:HGNC:21167|Ensembl:ENSG00000067840|Vega:OTTHUMG00000024209 +57596 BEGAIN HGNC:HGNC:24163|Ensembl:ENSG00000183092|Vega:OTTHUMG00000171589 +57597 BAHCC1 HGNC:HGNC:29279|Ensembl:ENSG00000266074|Vega:OTTHUMG00000184171 +57599 WDR48 MIM:612167|HGNC:HGNC:30914|Ensembl:ENSG00000114742|Vega:OTTHUMG00000155972 +57600 FNIP2 MIM:612768|HGNC:HGNC:29280|Ensembl:ENSG00000052795|Vega:OTTHUMG00000161983 +57602 USP36 MIM:612543|HGNC:HGNC:20062|Ensembl:ENSG00000055483|Vega:OTTHUMG00000177542 +57604 KIAA1456 MIM:615666|HGNC:HGNC:26725|Ensembl:ENSG00000250305|Vega:OTTHUMG00000165477 +57605 PITPNM2 MIM:608920|HGNC:HGNC:21044|Ensembl:ENSG00000090975|Vega:OTTHUMG00000168845 +57606 SLAIN2 MIM:610492|HGNC:HGNC:29282|Ensembl:ENSG00000109171|Vega:OTTHUMG00000161701 +57608 JCAD MIM:614398|HGNC:HGNC:29283|Ensembl:ENSG00000165757|Vega:OTTHUMG00000017885 +57609 DIP2B MIM:611379|HGNC:HGNC:29284|Ensembl:ENSG00000066084|Vega:OTTHUMG00000169475 +57610 RANBP10 MIM:614031|HGNC:HGNC:29285|Ensembl:ENSG00000141084|Vega:OTTHUMG00000184044 +57611 ISLR2 MIM:614179|HGNC:HGNC:29286|Ensembl:ENSG00000167178|Vega:OTTHUMG00000137624 +57612 ERV3-2 HGNC:HGNC:22218 +57613 FAM234B HGNC:HGNC:29288|Ensembl:ENSG00000084444|Vega:OTTHUMG00000168774 +57614 KIAA1468 HGNC:HGNC:29289|Ensembl:ENSG00000134444|Vega:OTTHUMG00000132780 +57615 ZNF492 HGNC:HGNC:23707|Ensembl:ENSG00000229676|Vega:OTTHUMG00000182987 +57616 TSHZ3 MIM:614119|HGNC:HGNC:30700|Ensembl:ENSG00000121297|Vega:OTTHUMG00000150184 +57617 VPS18 MIM:608551|HGNC:HGNC:15972|Ensembl:ENSG00000104142|Vega:OTTHUMG00000130135 +57619 SHROOM3 MIM:604570|HGNC:HGNC:30422|Ensembl:ENSG00000138771|Vega:OTTHUMG00000157075 +57620 STIM2 MIM:610841|HGNC:HGNC:19205|Ensembl:ENSG00000109689|Vega:OTTHUMG00000097805 +57621 ZBTB2 MIM:616595|HGNC:HGNC:20868|Ensembl:ENSG00000181472|Vega:OTTHUMG00000015834 +57622 LRFN1 MIM:612807|HGNC:HGNC:29290|Ensembl:ENSG00000128011|Vega:OTTHUMG00000182808 +57623 ZFAT MIM:610931|HGNC:HGNC:19899|Ensembl:ENSG00000066827|Vega:OTTHUMG00000164321 +57624 NYAP2 MIM:615478|HGNC:HGNC:29291|Ensembl:ENSG00000144460|Vega:OTTHUMG00000153450 +57626 KLHL1 MIM:605332|HGNC:HGNC:6352|Ensembl:ENSG00000150361|Vega:OTTHUMG00000017056 +57628 DPP10 MIM:608209|HGNC:HGNC:20823|Ensembl:ENSG00000175497|Vega:OTTHUMG00000153294 +57630 SH3RF1 HGNC:HGNC:17650|Ensembl:ENSG00000154447|Vega:OTTHUMG00000161010 +57631 LRCH2 HGNC:HGNC:29292|Ensembl:ENSG00000130224|Vega:OTTHUMG00000022233 +57633 LRRN1 HGNC:HGNC:20980|Ensembl:ENSG00000175928|Vega:OTTHUMG00000154934 +57634 EP400 MIM:606265|HGNC:HGNC:11958|Ensembl:ENSG00000183495|Vega:OTTHUMG00000187346 +57636 ARHGAP23 MIM:610590|HGNC:HGNC:29293|Ensembl:ENSG00000275832|Vega:OTTHUMG00000188547 +57639 CCDC146 HGNC:HGNC:29296|Ensembl:ENSG00000135205|Vega:OTTHUMG00000162595 +57642 COL20A1 HGNC:HGNC:14670|Ensembl:ENSG00000101203|Vega:OTTHUMG00000032964 +57643 ZSWIM5 HGNC:HGNC:29299|Ensembl:ENSG00000162415|Vega:OTTHUMG00000008950 +57644 MYH7B MIM:609928|HGNC:HGNC:15906|Ensembl:ENSG00000078814|Vega:OTTHUMG00000032320 +57645 POGK HGNC:HGNC:18800|Ensembl:ENSG00000143157|Vega:OTTHUMG00000034325 +57646 USP28 MIM:610748|HGNC:HGNC:12625|Ensembl:ENSG00000048028|Vega:OTTHUMG00000168205 +57647 DHX37 MIM:617362|HGNC:HGNC:17210|Ensembl:ENSG00000150990|Vega:OTTHUMG00000168547 +57648 KIAA1522 HGNC:HGNC:29301|Ensembl:ENSG00000162522|Vega:OTTHUMG00000008088 +57649 PHF12 HGNC:HGNC:20816|Ensembl:ENSG00000109118|Vega:OTTHUMG00000132676 +57650 CIP2A MIM:610643|HGNC:HGNC:29302|Ensembl:ENSG00000163507|Vega:OTTHUMG00000159233 +57653 LOC100499484-C9ORF174 Ensembl:ENSG00000255036 +57654 UVSSA MIM:614632|HGNC:HGNC:29304|Ensembl:ENSG00000163945|Vega:OTTHUMG00000160167 +57655 GRAMD1A HGNC:HGNC:29305|Ensembl:ENSG00000089351|Vega:OTTHUMG00000182464 +57657 HCN3 MIM:609973|HGNC:HGNC:19183|Ensembl:ENSG00000143630|Vega:OTTHUMG00000035872 +57658 CALCOCO1 HGNC:HGNC:29306|Ensembl:ENSG00000012822|Vega:OTTHUMG00000170095 +57659 ZBTB4 MIM:612308|HGNC:HGNC:23847|Ensembl:ENSG00000174282|Vega:OTTHUMG00000108137 +57661 PHRF1 MIM:611780|HGNC:HGNC:24351|Ensembl:ENSG00000070047|Vega:OTTHUMG00000165141 +57662 CAMSAP3 MIM:612685|HGNC:HGNC:29307|Ensembl:ENSG00000076826|Vega:OTTHUMG00000182096 +57663 USP29 MIM:609546|HGNC:HGNC:18563|Ensembl:ENSG00000131864|Vega:OTTHUMG00000183101 +57664 PLEKHA4 MIM:607769|HGNC:HGNC:14339|Ensembl:ENSG00000105559|Vega:OTTHUMG00000183329 +57665 RDH14 MIM:616796|HGNC:HGNC:19979|Ensembl:ENSG00000240857|Vega:OTTHUMG00000090705 +57666 FBRSL1 HGNC:HGNC:29308|Ensembl:ENSG00000112787|Vega:OTTHUMG00000167991 +57669 EPB41L5 MIM:611730|HGNC:HGNC:19819|Ensembl:ENSG00000115109|Vega:OTTHUMG00000131433 +57670 KIAA1549 MIM:613344|HGNC:HGNC:22219|Ensembl:ENSG00000122778|Vega:OTTHUMG00000157214 +57673 BEND3 MIM:616374|HGNC:HGNC:23040|Ensembl:ENSG00000178409|Vega:OTTHUMG00000015308 +57674 RNF213 MIM:613768|HGNC:HGNC:14539|Ensembl:ENSG00000173821|Vega:OTTHUMG00000161415 +57677 ZFP14 HGNC:HGNC:29312|Ensembl:ENSG00000142065|Vega:OTTHUMG00000180675 +57678 GPAM MIM:602395|HGNC:HGNC:24865|Ensembl:ENSG00000119927|Vega:OTTHUMG00000019055 +57679 ALS2 MIM:606352|HGNC:HGNC:443|Ensembl:ENSG00000003393|Vega:OTTHUMG00000154507 +57680 CHD8 MIM:610528|HGNC:HGNC:20153|Ensembl:ENSG00000100888|Vega:OTTHUMG00000170759 +57683 ZDBF2 MIM:617059|HGNC:HGNC:29313|Ensembl:ENSG00000204186|Vega:OTTHUMG00000154648 +57684 ZBTB26 HGNC:HGNC:23383|Ensembl:ENSG00000171448|Vega:OTTHUMG00000020627 +57685 CACHD1 HGNC:HGNC:29314|Ensembl:ENSG00000158966|Vega:OTTHUMG00000009030 +57687 VAT1L HGNC:HGNC:29315|Ensembl:ENSG00000171724|Vega:OTTHUMG00000176845 +57688 ZSWIM6 MIM:615951|HGNC:HGNC:29316|Ensembl:ENSG00000130449|Vega:OTTHUMG00000162388 +57689 LRRC4C MIM:608817|HGNC:HGNC:29317|Ensembl:ENSG00000148948|Vega:OTTHUMG00000166383 +57690 TNRC6C MIM:610741|HGNC:HGNC:29318|Ensembl:ENSG00000078687|Vega:OTTHUMG00000132642 +57691 KIAA1586 HGNC:HGNC:21360|Ensembl:ENSG00000168116|Vega:OTTHUMG00000014915 +57692 MAGEE1 MIM:300759|HGNC:HGNC:24934|Ensembl:ENSG00000198934|Vega:OTTHUMG00000021879 +57693 ZNF317 MIM:613864|HGNC:HGNC:13507|Ensembl:ENSG00000130803|Vega:OTTHUMG00000179932 +57695 USP37 HGNC:HGNC:20063|Ensembl:ENSG00000135913|Vega:OTTHUMG00000133113 +57696 DDX55 HGNC:HGNC:20085|Ensembl:ENSG00000111364|Vega:OTTHUMG00000168695 +57697 FANCM MIM:609644|HGNC:HGNC:23168|Ensembl:ENSG00000187790|Vega:OTTHUMG00000170807 +57698 SHTN1 MIM:611171|HGNC:HGNC:29319|Ensembl:ENSG00000187164|Vega:OTTHUMG00000019114 +57699 CPNE5 MIM:604209|HGNC:HGNC:2318|Ensembl:ENSG00000124772|Vega:OTTHUMG00000014602 +57700 FAM160B1 MIM:617312|HGNC:HGNC:29320|Ensembl:ENSG00000151553|Vega:OTTHUMG00000019092 +57701 NCKAP5L MIM:615104|HGNC:HGNC:29321|Ensembl:ENSG00000167566|Vega:OTTHUMG00000156969 +57703 CWC22 MIM:615186|HGNC:HGNC:29322|Ensembl:ENSG00000163510|Vega:OTTHUMG00000154244 +57704 GBA2 MIM:609471|HGNC:HGNC:18986|Ensembl:ENSG00000070610|Vega:OTTHUMG00000021024 +57705 WDFY4 MIM:613316|HGNC:HGNC:29323|Ensembl:ENSG00000128815 +57706 DENND1A MIM:613633|HGNC:HGNC:29324|Ensembl:ENSG00000119522|Vega:OTTHUMG00000020643 +57707 TLDC1 HGNC:HGNC:29325|Ensembl:ENSG00000140950|Vega:OTTHUMG00000176739 +57708 MIER1 MIM:616848|HGNC:HGNC:29657|Ensembl:ENSG00000198160|Vega:OTTHUMG00000009194 +57709 SLC7A14 MIM:615720|HGNC:HGNC:29326|Ensembl:ENSG00000013293|Vega:OTTHUMG00000158941 +57710 KIAA1614 HGNC:HGNC:29327|Ensembl:ENSG00000135835|Vega:OTTHUMG00000035183 +57711 ZNF529 HGNC:HGNC:29328|Ensembl:ENSG00000186020|Vega:OTTHUMG00000180714 +57713 SFMBT2 MIM:615392|HGNC:HGNC:20256|Ensembl:ENSG00000198879|Vega:OTTHUMG00000017630 +57715 SEMA4G HGNC:HGNC:10735|Ensembl:ENSG00000095539|Vega:OTTHUMG00000018922 +57716 PRX MIM:605725|HGNC:HGNC:13797|Ensembl:ENSG00000105227|Vega:OTTHUMG00000182597 +57717 PCDHB16 MIM:606345|HGNC:HGNC:14546|Ensembl:ENSG00000272674|Vega:OTTHUMG00000188325 +57718 PPP4R4 MIM:616790|HGNC:HGNC:23788|Ensembl:ENSG00000119698|Vega:OTTHUMG00000171344 +57719 ANO8 MIM:610216|HGNC:HGNC:29329|Ensembl:ENSG00000074855|Vega:OTTHUMG00000182665 +57720 GPR107 HGNC:HGNC:17830|Ensembl:ENSG00000148358|Vega:OTTHUMG00000020804 +57721 METTL14 MIM:616504|HGNC:HGNC:29330|Ensembl:ENSG00000145388|Vega:OTTHUMG00000161167 +57722 IGDCC4 MIM:616810|HGNC:HGNC:13770|Ensembl:ENSG00000103742|Vega:OTTHUMG00000133136 +57724 EPG5 MIM:615068|HGNC:HGNC:29331|Ensembl:ENSG00000152223|Vega:OTTHUMG00000132626 +57727 NCOA5 MIM:616825|HGNC:HGNC:15909|Ensembl:ENSG00000124160|Vega:OTTHUMG00000032639 +57728 WDR19 MIM:608151|HGNC:HGNC:18340|Ensembl:ENSG00000157796|Vega:OTTHUMG00000160466 +57730 ANKRD36B HGNC:HGNC:29333|Ensembl:ENSG00000196912|Vega:OTTHUMG00000130547 +57731 SPTBN4 MIM:606214|HGNC:HGNC:14896|Ensembl:ENSG00000160460|Vega:OTTHUMG00000182592 +57732 ZFYVE28 MIM:614176|HGNC:HGNC:29334|Ensembl:ENSG00000159733|Vega:OTTHUMG00000160292 +57733 GBA3 MIM:606619|HGNC:HGNC:19069|Ensembl:ENSG00000249948|Vega:OTTHUMG00000160448 +57758 SCUBE2 MIM:611747|HGNC:HGNC:30425|Ensembl:ENSG00000175356|Vega:OTTHUMG00000163880 +57760 SPG16 MIM:300266|HGNC:HGNC:14260 +57761 TRIB3 MIM:607898|HGNC:HGNC:16228|Ensembl:ENSG00000101255|Vega:OTTHUMG00000031627 +57762 NS2 MIM:605275 +57763 ANKRA2 MIM:605787|HGNC:HGNC:13208|Ensembl:ENSG00000164331|Vega:OTTHUMG00000102030 +57786 RBAK MIM:608191|HGNC:HGNC:17680|Ensembl:ENSG00000146587|Vega:OTTHUMG00000121155 +57787 MARK4 MIM:606495|HGNC:HGNC:13538|Ensembl:ENSG00000007047|Vega:OTTHUMG00000181769 +57788 RFMN MIM:300258 +57789 MTBSX MIM:300259 +57790 MRXSL MIM:300260 +57791 MRXSA MIM:300261 +57792 MRXSAB MIM:300262 +57794 SUGP1 MIM:607992|HGNC:HGNC:18643|Ensembl:ENSG00000105705|Vega:OTTHUMG00000182223 +57795 BRINP2 HGNC:HGNC:13746|Ensembl:ENSG00000198797|Vega:OTTHUMG00000034953 +57798 GATAD1 MIM:614518|HGNC:HGNC:29941|Ensembl:ENSG00000157259|Vega:OTTHUMG00000131201 +57799 RAB40C HGNC:HGNC:18285|Ensembl:ENSG00000197562|Vega:OTTHUMG00000047854 +57801 HES4 MIM:608060|HGNC:HGNC:24149|Ensembl:ENSG00000188290|Vega:OTTHUMG00000040758 +57804 POLD4 MIM:611525|HGNC:HGNC:14106|Ensembl:ENSG00000175482|Vega:OTTHUMG00000167135 +57805 CCAR2 MIM:607359|HGNC:HGNC:23360|Ensembl:ENSG00000158941|Vega:OTTHUMG00000162249 +57817 HAMP MIM:606464|HGNC:HGNC:15598|Ensembl:ENSG00000105697|Vega:OTTHUMG00000183295 +57818 G6PC2 MIM:608058|HGNC:HGNC:28906|Ensembl:ENSG00000152254|Vega:OTTHUMG00000132182 +57819 LSM2 MIM:607282|HGNC:HGNC:13940|Ensembl:ENSG00000204392|Vega:OTTHUMG00000031121 +57820 CCNB1IP1 MIM:608249|HGNC:HGNC:19437|Ensembl:ENSG00000100814|Vega:OTTHUMG00000029509 +57821 CCDC181 HGNC:HGNC:28051|Ensembl:ENSG00000117477|Vega:OTTHUMG00000035448 +57822 GRHL3 MIM:608317|HGNC:HGNC:25839|Ensembl:ENSG00000158055|Vega:OTTHUMG00000003040 +57823 SLAMF7 MIM:606625|HGNC:HGNC:21394|Ensembl:ENSG00000026751|Vega:OTTHUMG00000024008 +57824 HMHB1 MIM:609961|HGNC:HGNC:29677|Ensembl:ENSG00000158497|Vega:OTTHUMG00000163173 +57826 RAP2C HGNC:HGNC:21165|Ensembl:ENSG00000123728|Vega:OTTHUMG00000022424 +57827 C6orf47 HGNC:HGNC:19076|Ensembl:ENSG00000204439|Vega:OTTHUMG00000031172 +57828 CATSPERG MIM:613452|HGNC:HGNC:25243|Ensembl:ENSG00000099338|Vega:OTTHUMG00000153223 +57829 ZP4 MIM:613514|HGNC:HGNC:15770|Ensembl:ENSG00000116996|Vega:OTTHUMG00000039586 +57830 KRTAP5-8 HGNC:HGNC:23603|Ensembl:ENSG00000241233|Vega:OTTHUMG00000057571 +57834 CYP4F11 MIM:611517|HGNC:HGNC:13265|Ensembl:ENSG00000171903|Vega:OTTHUMG00000182294 +57835 SLC4A5 MIM:606757|HGNC:HGNC:18168|Ensembl:ENSG00000188687|Vega:OTTHUMG00000090263 +57862 ZNF410 HGNC:HGNC:20144|Ensembl:ENSG00000119725|Vega:OTTHUMG00000171257 +57863 CADM3 MIM:609743|HGNC:HGNC:17601|Ensembl:ENSG00000162706|Vega:OTTHUMG00000037177 +57864 SLC46A2 MIM:608956|HGNC:HGNC:16055|Ensembl:ENSG00000119457|Vega:OTTHUMG00000020513 +57876 MUC3B MIM:605633|HGNC:HGNC:13384 +58155 PTBP2 MIM:608449|HGNC:HGNC:17662|Ensembl:ENSG00000117569|Vega:OTTHUMG00000010685 +58156 OPA4 MIM:605293|HGNC:HGNC:32786 +58157 NGB MIM:605304|HGNC:HGNC:14077|Ensembl:ENSG00000165553|Vega:OTTHUMG00000171558 +58158 NEUROD4 MIM:611635|HGNC:HGNC:13802|Ensembl:ENSG00000123307|Vega:OTTHUMG00000169826 +58160 NFE4 MIM:612133|HGNC:HGNC:29902|Ensembl:ENSG00000230257 +58163 RBPJP4 HGNC:HGNC:13687 +58164 RBPJP3 HGNC:HGNC:13686 +58189 WFDC1 MIM:605322|HGNC:HGNC:15466|Ensembl:ENSG00000103175|Vega:OTTHUMG00000137641 +58190 CTDSP1 MIM:605323|HGNC:HGNC:21614|Ensembl:ENSG00000144579|Vega:OTTHUMG00000133109 +58191 CXCL16 MIM:605398|HGNC:HGNC:16642|Ensembl:ENSG00000161921|Vega:OTTHUMG00000090761 +58472 SQOR HGNC:HGNC:20390|Ensembl:ENSG00000137767|Vega:OTTHUMG00000131476 +58473 PLEKHB1 MIM:607651|HGNC:HGNC:19079|Ensembl:ENSG00000021300|Vega:OTTHUMG00000168030 +58475 MS4A7 MIM:606502|HGNC:HGNC:13378|Ensembl:ENSG00000166927|Vega:OTTHUMG00000167356 +58476 TP53INP2 MIM:617549|HGNC:HGNC:16104|Ensembl:ENSG00000078804|Vega:OTTHUMG00000032310 +58477 SRPRB MIM:616883|HGNC:HGNC:24085|Ensembl:ENSG00000144867|Vega:OTTHUMG00000159753 +58478 ENOPH1 HGNC:HGNC:24599|Ensembl:ENSG00000145293|Vega:OTTHUMG00000130295 +58480 RHOU MIM:606366|HGNC:HGNC:17794|Ensembl:ENSG00000116574|Vega:OTTHUMG00000037919 +58483 LINC00474 HGNC:HGNC:23367 +58484 NLRC4 MIM:606831|HGNC:HGNC:16412|Ensembl:ENSG00000091106|Vega:OTTHUMG00000152107 +58485 TRAPPC1 MIM:610969|HGNC:HGNC:19894|Ensembl:ENSG00000170043|Vega:OTTHUMG00000108171 +58486 ZBED5 MIM:615251|HGNC:HGNC:30803|Ensembl:ENSG00000236287|Vega:OTTHUMG00000150341 +58487 CREBZF MIM:606444|HGNC:HGNC:24905|Ensembl:ENSG00000137504|Vega:OTTHUMG00000133648 +58488 PCTP MIM:606055|HGNC:HGNC:8752|Ensembl:ENSG00000141179|Vega:OTTHUMG00000177859 +58489 ABHD17C HGNC:HGNC:26925|Ensembl:ENSG00000136379|Vega:OTTHUMG00000172282 +58490 RPRD1B MIM:614694|HGNC:HGNC:16209|Ensembl:ENSG00000101413|Vega:OTTHUMG00000032434 +58491 ZNF71 MIM:194545|HGNC:HGNC:13141|Ensembl:ENSG00000197951|Vega:OTTHUMG00000182157 +58492 ZNF77 MIM:194551|HGNC:HGNC:13150|Ensembl:ENSG00000175691|Vega:OTTHUMG00000180566 +58493 INIP MIM:613273|HGNC:HGNC:24994|Ensembl:ENSG00000148153|Vega:OTTHUMG00000020509 +58494 JAM2 MIM:606870|HGNC:HGNC:14686|Ensembl:ENSG00000154721|Vega:OTTHUMG00000078441 +58495 OVOL2 MIM:616441|HGNC:HGNC:15804|Ensembl:ENSG00000125850|Vega:OTTHUMG00000031960 +58496 LY6G5B MIM:610433|HGNC:HGNC:13931|Ensembl:ENSG00000240053|Ensembl:ENSG00000263020|Vega:OTTHUMG00000031056|Vega:OTTHUMG00000031227 +58497 PRUNE1 MIM:617413|HGNC:HGNC:13420|Ensembl:ENSG00000143363|Vega:OTTHUMG00000035062 +58498 MYL7 MIM:613993|HGNC:HGNC:21719|Ensembl:ENSG00000106631|Vega:OTTHUMG00000023125 +58499 ZNF462 MIM:617371|HGNC:HGNC:21684|Ensembl:ENSG00000148143|Vega:OTTHUMG00000020438 +58500 ZNF250 HGNC:HGNC:13044|Ensembl:ENSG00000196150|Vega:OTTHUMG00000165252 +58503 OPRPN MIM:608936|HGNC:HGNC:17279|Ensembl:ENSG00000171199|Vega:OTTHUMG00000160845 +58504 ARHGAP22 MIM:610585|HGNC:HGNC:30320|Ensembl:ENSG00000128805|Vega:OTTHUMG00000018176 +58505 OSTC HGNC:HGNC:24448|Ensembl:ENSG00000198856|Vega:OTTHUMG00000161031 +58506 SCAF1 MIM:617264|HGNC:HGNC:30403|Ensembl:ENSG00000126461|Vega:OTTHUMG00000183238 +58508 KMT2C MIM:606833|HGNC:HGNC:13726|Ensembl:ENSG00000055609|Vega:OTTHUMG00000150553 +58509 CACTIN HGNC:HGNC:29938|Ensembl:ENSG00000105298|Vega:OTTHUMG00000180808 +58510 PRODH2 MIM:616377|HGNC:HGNC:17325|Ensembl:ENSG00000250799|Vega:OTTHUMG00000180688 +58511 DNASE2B MIM:608057|HGNC:HGNC:28875|Ensembl:ENSG00000137976|Vega:OTTHUMG00000009860 +58512 DLGAP3 MIM:611413|HGNC:HGNC:30368|Ensembl:ENSG00000116544|Vega:OTTHUMG00000004049 +58513 EPS15L1 MIM:616826|HGNC:HGNC:24634|Ensembl:ENSG00000127527|Vega:OTTHUMG00000182361 +58515 SELENOK MIM:607916|HGNC:HGNC:30394|Ensembl:ENSG00000113811|Vega:OTTHUMG00000158656 +58516 SINHCAF MIM:615027|HGNC:HGNC:30702|Ensembl:ENSG00000139146|Vega:OTTHUMG00000168586 +58517 RBM25 MIM:612427|HGNC:HGNC:23244|Ensembl:ENSG00000119707|Vega:OTTHUMG00000167540 +58524 DMRT3 MIM:614754|HGNC:HGNC:13909|Ensembl:ENSG00000064218|Vega:OTTHUMG00000019436 +58525 WIZ HGNC:HGNC:30917|Ensembl:ENSG00000011451|Vega:OTTHUMG00000182448 +58526 MID1IP1 MIM:300961|HGNC:HGNC:20715|Ensembl:ENSG00000165175|Vega:OTTHUMG00000024092 +58527 ABRACL HGNC:HGNC:21230|Ensembl:ENSG00000146386|Vega:OTTHUMG00000015684 +58528 RRAGD MIM:608268|HGNC:HGNC:19903|Ensembl:ENSG00000025039|Vega:OTTHUMG00000015200 +58529 MYOZ1 MIM:605603|HGNC:HGNC:13752|Ensembl:ENSG00000177791|Vega:OTTHUMG00000018466 +58530 LY6G6D MIM:606038|HGNC:HGNC:13935|Ensembl:ENSG00000244355|Vega:OTTHUMG00000137370 +58531 PRM3 HGNC:HGNC:13732|Ensembl:ENSG00000178257|Vega:OTTHUMG00000172316 +58533 SNX6 MIM:606098|HGNC:HGNC:14970|Ensembl:ENSG00000129515|Vega:OTTHUMG00000140213 +58538 MPP4 MIM:606575|HGNC:HGNC:13680|Ensembl:ENSG00000082126|Vega:OTTHUMG00000154525 +58985 IL22RA1 MIM:605457|HGNC:HGNC:13700|Ensembl:ENSG00000142677|Vega:OTTHUMG00000003041 +58986 TMEM8A HGNC:HGNC:17205|Ensembl:ENSG00000129925|Vega:OTTHUMG00000047996 +59067 IL21 MIM:605384|HGNC:HGNC:6005|Ensembl:ENSG00000138684|Vega:OTTHUMG00000133073 +59081 MNG2 MIM:300273 +59082 CARD18 MIM:605354|HGNC:HGNC:28861|Ensembl:ENSG00000255501|Vega:OTTHUMG00000166165 +59084 ENPP5 MIM:617001|HGNC:HGNC:13717|Ensembl:ENSG00000112796|Vega:OTTHUMG00000014781 +59269 HIVEP3 MIM:606649|HGNC:HGNC:13561|Ensembl:ENSG00000127124|Vega:OTTHUMG00000006361 +59271 EVA1C HGNC:HGNC:13239|Ensembl:ENSG00000166979|Vega:OTTHUMG00000064922 +59272 ACE2 MIM:300335|HGNC:HGNC:13557|Ensembl:ENSG00000130234|Vega:OTTHUMG00000021177 +59274 TLNRD1 MIM:615466|HGNC:HGNC:13519|Ensembl:ENSG00000140406|Vega:OTTHUMG00000144185 +59277 NTN4 MIM:610401|HGNC:HGNC:13658|Ensembl:ENSG00000074527|Vega:OTTHUMG00000170290 +59283 CACNG8 MIM:606900|HGNC:HGNC:13628|Ensembl:ENSG00000142408|Vega:OTTHUMG00000064908 +59284 CACNG7 MIM:606899|HGNC:HGNC:13626|Ensembl:ENSG00000105605|Vega:OTTHUMG00000064852 +59285 CACNG6 MIM:606898|HGNC:HGNC:13625|Ensembl:ENSG00000130433|Vega:OTTHUMG00000064907 +59286 UBL5 MIM:606849|HGNC:HGNC:13736|Ensembl:ENSG00000198258|Vega:OTTHUMG00000180214 +59307 SIGIRR MIM:605478|HGNC:HGNC:30575|Ensembl:ENSG00000185187|Vega:OTTHUMG00000165412 +59330 GER MIM:109350 +59331 RFH1 MIM:161900 +59332 VSPA MIM:313000 +59333 NMSR MIM:605285 +59335 PRDM12 MIM:616458|HGNC:HGNC:13997|Ensembl:ENSG00000130711|Vega:OTTHUMG00000020808 +59336 PRDM13 MIM:616741|HGNC:HGNC:13998|Ensembl:ENSG00000112238|Vega:OTTHUMG00000015269 +59338 PLEKHA1 MIM:607772|HGNC:HGNC:14335|Ensembl:ENSG00000107679|Vega:OTTHUMG00000019184 +59339 PLEKHA2 MIM:607773|HGNC:HGNC:14336|Ensembl:ENSG00000169499|Vega:OTTHUMG00000164069 +59340 HRH4 MIM:606792|HGNC:HGNC:17383|Ensembl:ENSG00000134489|Vega:OTTHUMG00000131945 +59341 TRPV4 MIM:605427|HGNC:HGNC:18083|Ensembl:ENSG00000111199|Vega:OTTHUMG00000169277 +59342 SCPEP1 HGNC:HGNC:29507|Ensembl:ENSG00000121064|Vega:OTTHUMG00000178129 +59343 SENP2 MIM:608261|HGNC:HGNC:23116|Ensembl:ENSG00000163904|Vega:OTTHUMG00000156658 +59344 ALOXE3 MIM:607206|HGNC:HGNC:13743|Ensembl:ENSG00000179148|Vega:OTTHUMG00000108179 +59345 GNB4 MIM:610863|HGNC:HGNC:20731|Ensembl:ENSG00000114450|Vega:OTTHUMG00000157440 +59347 TPT1P8 HGNC:HGNC:24088 +59348 ZNF350 MIM:605422|HGNC:HGNC:16656|Ensembl:ENSG00000256683|Vega:OTTHUMG00000182538 +59349 KLHL12 MIM:614522|HGNC:HGNC:19360|Ensembl:ENSG00000117153|Vega:OTTHUMG00000041385 +59350 RXFP1 MIM:606654|HGNC:HGNC:19718|Ensembl:ENSG00000171509|Vega:OTTHUMG00000149973 +59351 PBOV1 MIM:605669|HGNC:HGNC:21079|Ensembl:ENSG00000254440|Vega:OTTHUMG00000167040 +59352 LGR6 MIM:606653|HGNC:HGNC:19719|Ensembl:ENSG00000133067|Vega:OTTHUMG00000041383 +59353 TMEM35A HGNC:HGNC:25864|Ensembl:ENSG00000126950|Vega:OTTHUMG00000022016 +60312 AFAP1 MIM:608252|HGNC:HGNC:24017|Ensembl:ENSG00000196526|Vega:OTTHUMG00000125515 +60313 GPBP1L1 HGNC:HGNC:28843|Ensembl:ENSG00000159592|Vega:OTTHUMG00000040990 +60314 C12orf10 MIM:611366|HGNC:HGNC:17590|Ensembl:ENSG00000139637|Vega:OTTHUMG00000170030 +60343 FAM3A MIM:300492|HGNC:HGNC:13749|Ensembl:ENSG00000071889|Vega:OTTHUMG00000013418 +60358 ERVK-5 MIM:614012|HGNC:HGNC:13757 +60359 ERVK-4 MIM:614011|HGNC:HGNC:13756 +60370 AVPI1 HGNC:HGNC:30898|Ensembl:ENSG00000119986|Vega:OTTHUMG00000018864 +60385 TSKS MIM:608253|HGNC:HGNC:30719|Ensembl:ENSG00000126467|Vega:OTTHUMG00000183249 +60386 SLC25A19 MIM:606521|HGNC:HGNC:14409|Ensembl:ENSG00000125454|Vega:OTTHUMG00000179607 +60401 EDA2R MIM:300276|HGNC:HGNC:17756|Ensembl:ENSG00000131080|Vega:OTTHUMG00000021736 +60412 EXOC4 MIM:608185|HGNC:HGNC:30389|Ensembl:ENSG00000131558|Vega:OTTHUMG00000155259 +60436 TGIF2 MIM:607294|HGNC:HGNC:15764|Ensembl:ENSG00000118707|Vega:OTTHUMG00000172332 +60437 CDH26 HGNC:HGNC:15902|Ensembl:ENSG00000124215|Vega:OTTHUMG00000032874 +60439 TTTY2 HGNC:HGNC:14023 +60467 BPESC1 HGNC:HGNC:13228|Ensembl:ENSG00000232416 +60468 BACH2 MIM:605394|HGNC:HGNC:14078|Ensembl:ENSG00000112182|Vega:OTTHUMG00000015216 +60481 ELOVL5 MIM:611805|HGNC:HGNC:21308|Ensembl:ENSG00000012660|Vega:OTTHUMG00000016249 +60482 SLC5A7 MIM:608761|HGNC:HGNC:14025|Ensembl:ENSG00000115665|Vega:OTTHUMG00000130959 +60484 HAPLN2 HGNC:HGNC:17410|Ensembl:ENSG00000132702|Vega:OTTHUMG00000033205 +60485 SAV1 MIM:607203|HGNC:HGNC:17795|Ensembl:ENSG00000151748|Vega:OTTHUMG00000140293 +60487 TRMT11 HGNC:HGNC:21080|Ensembl:ENSG00000066651|Vega:OTTHUMG00000015515 +60488 MRPS35 MIM:611995|HGNC:HGNC:16635|Ensembl:ENSG00000061794|Vega:OTTHUMG00000169215 +60489 APOBEC3G MIM:607113|HGNC:HGNC:17357|Ensembl:ENSG00000239713|Vega:OTTHUMG00000151081 +60490 PPCDC MIM:609854|HGNC:HGNC:28107|Ensembl:ENSG00000138621|Vega:OTTHUMG00000142824 +60491 NIF3L1 MIM:605778|HGNC:HGNC:13390|Ensembl:ENSG00000196290|Vega:OTTHUMG00000154588 +60492 CCDC90B HGNC:HGNC:28108|Ensembl:ENSG00000137500|Vega:OTTHUMG00000167078 +60493 FASTKD5 MIM:614272|HGNC:HGNC:25790|Ensembl:ENSG00000215251|Vega:OTTHUMG00000031727 +60494 CCDC81 HGNC:HGNC:26281|Ensembl:ENSG00000149201|Vega:OTTHUMG00000167213 +60495 HPSE2 MIM:613469|HGNC:HGNC:18374|Ensembl:ENSG00000172987|Vega:OTTHUMG00000018880 +60496 AASDHPPT MIM:607756|HGNC:HGNC:14235|Ensembl:ENSG00000149313|Vega:OTTHUMG00000166253 +60498 IGAN1 MIM:161950 +60500 BRCA3 MIM:605365|HGNC:HGNC:18617 +60502 CPAT1 MIM:605388|HGNC:HGNC:30998 +60506 NYX MIM:300278|HGNC:HGNC:8082|Ensembl:ENSG00000188937|Vega:OTTHUMG00000021370 +60509 AGBL5 MIM:615900|HGNC:HGNC:26147|Ensembl:ENSG00000084693|Vega:OTTHUMG00000128406 +60526 LDAH MIM:613570|HGNC:HGNC:26145|Ensembl:ENSG00000118961|Vega:OTTHUMG00000122097 +60528 ELAC2 MIM:605367|HGNC:HGNC:14198|Ensembl:ENSG00000006744|Vega:OTTHUMG00000058764 +60529 ALX4 MIM:605420|HGNC:HGNC:450|Ensembl:ENSG00000052850|Vega:OTTHUMG00000166557 +60558 GUF1 MIM:617064|HGNC:HGNC:25799|Ensembl:ENSG00000151806|Vega:OTTHUMG00000128608 +60559 SPCS3 HGNC:HGNC:26212|Ensembl:ENSG00000129128|Vega:OTTHUMG00000160789 +60560 NAA35 HGNC:HGNC:24340|Ensembl:ENSG00000135040|Vega:OTTHUMG00000020131 +60561 RINT1 MIM:610089|HGNC:HGNC:21876|Ensembl:ENSG00000135249|Vega:OTTHUMG00000157400 +60592 SCOC HGNC:HGNC:20335|Ensembl:ENSG00000153130|Vega:OTTHUMG00000133416 +60598 KCNK15 MIM:607368|HGNC:HGNC:13814|Ensembl:ENSG00000124249|Vega:OTTHUMG00000032544 +60625 DHX35 HGNC:HGNC:15861|Ensembl:ENSG00000101452|Vega:OTTHUMG00000032463 +60626 RIC8A MIM:609146|HGNC:HGNC:29550|Ensembl:ENSG00000177963|Vega:OTTHUMG00000119069 +60672 MIIP MIM:608772|HGNC:HGNC:25715|Ensembl:ENSG00000116691|Vega:OTTHUMG00000002439 +60673 ATG101 MIM:615089|HGNC:HGNC:25679|Ensembl:ENSG00000123395|Vega:OTTHUMG00000169611 +60674 GAS5 MIM:608280|HGNC:HGNC:16355|Ensembl:ENSG00000234741 +60675 PROK2 MIM:607002|HGNC:HGNC:18455|Ensembl:ENSG00000163421|Vega:OTTHUMG00000158809 +60676 PAPPA2 HGNC:HGNC:14615|Ensembl:ENSG00000116183|Vega:OTTHUMG00000035025 +60677 CELF6 MIM:612681|HGNC:HGNC:14059|Ensembl:ENSG00000140488|Ensembl:ENSG00000273025|Vega:OTTHUMG00000133444|Vega:OTTHUMG00000186423 +60678 EEFSEC MIM:607695|HGNC:HGNC:24614|Ensembl:ENSG00000132394|Vega:OTTHUMG00000159659 +60680 CELF5 MIM:612680|HGNC:HGNC:14058|Ensembl:ENSG00000161082|Vega:OTTHUMG00000180693 +60681 FKBP10 MIM:607063|HGNC:HGNC:18169|Ensembl:ENSG00000141756|Vega:OTTHUMG00000133497 +60682 SMAP1 MIM:611372|HGNC:HGNC:19651|Ensembl:ENSG00000112305|Vega:OTTHUMG00000014996 +60684 TRAPPC11 MIM:614138|HGNC:HGNC:25751|Ensembl:ENSG00000168538|Vega:OTTHUMG00000160673 +60685 ZFAND3 MIM:607455|HGNC:HGNC:18019|Ensembl:ENSG00000156639|Vega:OTTHUMG00000014629 +60686 C14orf93 HGNC:HGNC:20162|Ensembl:ENSG00000100802|Vega:OTTHUMG00000028712 +63027 SLC22A23 MIM:611697|HGNC:HGNC:21106|Ensembl:ENSG00000137266|Vega:OTTHUMG00000014144 +63035 BCORL1 MIM:300688|HGNC:HGNC:25657|Ensembl:ENSG00000085185|Vega:OTTHUMG00000022379 +63036 CELA2A MIM:609443|HGNC:HGNC:24609|Ensembl:ENSG00000142615|Vega:OTTHUMG00000002258 +63826 SRR MIM:606477|HGNC:HGNC:14398|Ensembl:ENSG00000167720|Vega:OTTHUMG00000090583 +63827 BCAN MIM:600347|HGNC:HGNC:23059|Ensembl:ENSG00000132692|Vega:OTTHUMG00000033322 +63869 PSORS6 MIM:605364|HGNC:HGNC:33483 +63870 PSORS5 MIM:604316|HGNC:HGNC:17953 +63874 ABHD4 HGNC:HGNC:20154|Ensembl:ENSG00000100439|Vega:OTTHUMG00000028686 +63875 MRPL17 MIM:611830|HGNC:HGNC:14053|Ensembl:ENSG00000158042|Vega:OTTHUMG00000165505 +63876 PKNOX2 MIM:613066|HGNC:HGNC:16714|Ensembl:ENSG00000165495|Vega:OTTHUMG00000165884 +63877 FAM204A HGNC:HGNC:25794|Ensembl:ENSG00000165669|Vega:OTTHUMG00000019131 +63891 RNF123 MIM:614472|HGNC:HGNC:21148|Ensembl:ENSG00000164068|Vega:OTTHUMG00000156891 +63892 THADA MIM:611800|HGNC:HGNC:19217|Ensembl:ENSG00000115970|Vega:OTTHUMG00000152398 +63893 UBE2O HGNC:HGNC:29554|Ensembl:ENSG00000175931|Vega:OTTHUMG00000180178 +63894 VIPAS39 MIM:613401|HGNC:HGNC:20347|Ensembl:ENSG00000151445|Vega:OTTHUMG00000171538 +63895 PIEZO2 MIM:613629|HGNC:HGNC:26270|Ensembl:ENSG00000154864|Vega:OTTHUMG00000178507 +63897 HEATR6 HGNC:HGNC:24076|Ensembl:ENSG00000068097|Vega:OTTHUMG00000179981 +63898 SH2D4A MIM:614968|HGNC:HGNC:26102|Ensembl:ENSG00000104611|Vega:OTTHUMG00000097005 +63899 NSUN3 MIM:617491|HGNC:HGNC:26208|Ensembl:ENSG00000178694|Vega:OTTHUMG00000159025 +63901 FAM111A MIM:615292|HGNC:HGNC:24725|Ensembl:ENSG00000166801|Vega:OTTHUMG00000167280 +63904 DUSP21 MIM:300678|HGNC:HGNC:20476|Ensembl:ENSG00000189037|Vega:OTTHUMG00000021401 +63905 MANBAL HGNC:HGNC:15799|Ensembl:ENSG00000101363|Vega:OTTHUMG00000032414 +63906 GPATCH3 MIM:617486|HGNC:HGNC:25720|Ensembl:ENSG00000198746|Vega:OTTHUMG00000004229 +63908 NAPB MIM:611270|HGNC:HGNC:15751|Ensembl:ENSG00000125814|Vega:OTTHUMG00000032062 +63910 SLC17A9 MIM:612107|HGNC:HGNC:16192|Ensembl:ENSG00000101194|Vega:OTTHUMG00000032951 +63914 LINC01590 HGNC:HGNC:21404|Ensembl:ENSG00000111850 +63915 BLOC1S5 MIM:607289|HGNC:HGNC:18561|Ensembl:ENSG00000188428|Vega:OTTHUMG00000014220 +63916 ELMO2 MIM:606421|HGNC:HGNC:17233|Ensembl:ENSG00000062598|Vega:OTTHUMG00000033070 +63917 GALNT11 MIM:615130|HGNC:HGNC:19875|Ensembl:ENSG00000178234|Vega:OTTHUMG00000157251 +63920 ZBED8 MIM:615253|HGNC:HGNC:30804|Ensembl:ENSG00000221886|Vega:OTTHUMG00000163554 +63922 CHTF18 MIM:613201|HGNC:HGNC:18435|Ensembl:ENSG00000127586|Vega:OTTHUMG00000047838 +63923 TNN MIM:617472|HGNC:HGNC:22942|Ensembl:ENSG00000120332|Vega:OTTHUMG00000034882 +63924 CIDEC MIM:612120|HGNC:HGNC:24229|Ensembl:ENSG00000187288|Vega:OTTHUMG00000128522 +63925 ZNF335 MIM:610827|HGNC:HGNC:15807|Ensembl:ENSG00000198026|Vega:OTTHUMG00000032637 +63926 ANKEF1 HGNC:HGNC:15803|Ensembl:ENSG00000132623|Vega:OTTHUMG00000031860 +63928 CHP2 HGNC:HGNC:24927|Ensembl:ENSG00000166869|Vega:OTTHUMG00000131611 +63929 XPNPEP3 MIM:613553|HGNC:HGNC:28052|Ensembl:ENSG00000196236|Vega:OTTHUMG00000151312 +63930 LINC01749 HGNC:HGNC:52537|Ensembl:ENSG00000272259 +63931 MRPS14 MIM:611978|HGNC:HGNC:14049|Ensembl:ENSG00000120333|Vega:OTTHUMG00000034878 +63932 CXorf56 HGNC:HGNC:26239|Ensembl:ENSG00000018610|Vega:OTTHUMG00000022276 +63933 MCUR1 MIM:616952|HGNC:HGNC:21097|Ensembl:ENSG00000050393|Vega:OTTHUMG00000014279 +63934 ZNF667 MIM:611024|HGNC:HGNC:28854|Ensembl:ENSG00000198046|Vega:OTTHUMG00000181941 +63935 PCIF1 HGNC:HGNC:16200|Ensembl:ENSG00000100982|Vega:OTTHUMG00000032635 +63939 FAM217B HGNC:HGNC:16170|Ensembl:ENSG00000196227|Vega:OTTHUMG00000032873 +63940 GPSM3 HGNC:HGNC:13945|Ensembl:ENSG00000213654|Vega:OTTHUMG00000031244 +63941 NECAB3 MIM:612478|HGNC:HGNC:15851|Ensembl:ENSG00000125967|Vega:OTTHUMG00000032264 +63943 FKBPL MIM:617076|HGNC:HGNC:13949|Ensembl:ENSG00000204315|Vega:OTTHUMG00000031129 +63944 SCZD10 MIM:605419|HGNC:HGNC:17339 +63945 DFNA40 HGNC:HGNC:14070 +63946 DMRTC2 MIM:614806|HGNC:HGNC:13911|Ensembl:ENSG00000142025|Vega:OTTHUMG00000182675 +63947 DMRTC1 MIM:300878|HGNC:HGNC:13910|Ensembl:ENSG00000269502|Vega:OTTHUMG00000021820 +63948 DMRTB1 MIM:614805|HGNC:HGNC:13913|Ensembl:ENSG00000143006|Vega:OTTHUMG00000008080 +63950 DMRTA2 MIM:614804|HGNC:HGNC:13908|Ensembl:ENSG00000142700|Vega:OTTHUMG00000007884 +63951 DMRTA1 MIM:614803|HGNC:HGNC:13826|Ensembl:ENSG00000176399|Vega:OTTHUMG00000019693 +63967 CLSPN MIM:605434|HGNC:HGNC:19715|Ensembl:ENSG00000092853|Vega:OTTHUMG00000004168 +63970 TP53AIP1 MIM:605426|HGNC:HGNC:29984|Ensembl:ENSG00000120471|Vega:OTTHUMG00000165797 +63971 KIF13A MIM:605433|HGNC:HGNC:14566|Ensembl:ENSG00000137177|Vega:OTTHUMG00000014313 +63973 NEUROG2 MIM:606624|HGNC:HGNC:13805|Ensembl:ENSG00000178403|Vega:OTTHUMG00000132907 +63974 NEUROD6 MIM:611513|HGNC:HGNC:13804|Ensembl:ENSG00000164600|Vega:OTTHUMG00000022865 +63976 PRDM16 MIM:605557|HGNC:HGNC:14000|Ensembl:ENSG00000142611|Vega:OTTHUMG00000000581 +63977 PRDM15 HGNC:HGNC:13999|Ensembl:ENSG00000141956|Vega:OTTHUMG00000086781 +63978 PRDM14 MIM:611781|HGNC:HGNC:14001|Ensembl:ENSG00000147596|Vega:OTTHUMG00000150495 +63979 FIGNL1 MIM:615383|HGNC:HGNC:13286|Ensembl:ENSG00000132436|Vega:OTTHUMG00000022866 +63982 ANO3 MIM:610110|HGNC:HGNC:14004|Ensembl:ENSG00000134343|Vega:OTTHUMG00000166096 +64002 PCGEM1 MIM:605443|HGNC:HGNC:30145|Ensembl:ENSG00000227418 +64005 MYO1G MIM:600642|HGNC:HGNC:13880|Ensembl:ENSG00000136286|Vega:OTTHUMG00000155821 +64006 ERVK-6 MIM:605626|HGNC:HGNC:13915 +64061 TSPYL2 MIM:300564|HGNC:HGNC:24358|Ensembl:ENSG00000184205|Vega:OTTHUMG00000021597 +64062 RBM26 HGNC:HGNC:20327|Ensembl:ENSG00000139746|Vega:OTTHUMG00000017133 +64063 PRSS22 MIM:609343|HGNC:HGNC:14368|Ensembl:ENSG00000005001|Vega:OTTHUMG00000128961 +64064 OXCT2 MIM:610289|HGNC:HGNC:18606|Ensembl:ENSG00000198754|Vega:OTTHUMG00000009249 +64065 PERP MIM:609301|HGNC:HGNC:17637|Ensembl:ENSG00000112378|Vega:OTTHUMG00000015668 +64066 MMP27 HGNC:HGNC:14250|Ensembl:ENSG00000137675|Vega:OTTHUMG00000168099 +64067 NPAS3 MIM:609430|HGNC:HGNC:19311|Ensembl:ENSG00000151322|Vega:OTTHUMG00000140215 +64069 ATOD1 MIM:603165 +64072 CDH23 MIM:605516|HGNC:HGNC:13733|Ensembl:ENSG00000107736|Vega:OTTHUMG00000019347 +64073 C19orf33 HGNC:HGNC:16668|Ensembl:ENSG00000167644|Vega:OTTHUMG00000181894 +64077 LHPP MIM:617231|HGNC:HGNC:30042|Ensembl:ENSG00000107902|Vega:OTTHUMG00000019214 +64078 SLC28A3 MIM:608269|HGNC:HGNC:16484|Ensembl:ENSG00000197506|Vega:OTTHUMG00000020117 +64080 RBKS MIM:611132|HGNC:HGNC:30325|Ensembl:ENSG00000171174|Vega:OTTHUMG00000097833 +64081 PBLD MIM:612189|HGNC:HGNC:23301|Ensembl:ENSG00000108187|Vega:OTTHUMG00000073949 +64083 GOLPH3 MIM:612207|HGNC:HGNC:15452|Ensembl:ENSG00000113384|Vega:OTTHUMG00000090679 +64084 CLSTN2 MIM:611323|HGNC:HGNC:17448|Ensembl:ENSG00000158258|Vega:OTTHUMG00000160139 +64087 MCCC2 MIM:609014|HGNC:HGNC:6937|Ensembl:ENSG00000131844|Vega:OTTHUMG00000162505 +64089 SNX16 MIM:614903|HGNC:HGNC:14980|Ensembl:ENSG00000104497|Vega:OTTHUMG00000164727 +64090 GAL3ST2 MIM:608237|HGNC:HGNC:24869|Ensembl:ENSG00000154252|Vega:OTTHUMG00000151473 +64091 POPDC2 MIM:605823|HGNC:HGNC:17648|Ensembl:ENSG00000121577|Vega:OTTHUMG00000159438 +64092 SAMSN1 MIM:607978|HGNC:HGNC:10528|Ensembl:ENSG00000155307|Vega:OTTHUMG00000074317 +64093 SMOC1 MIM:608488|HGNC:HGNC:20318|Ensembl:ENSG00000198732|Vega:OTTHUMG00000171237 +64094 SMOC2 MIM:607223|HGNC:HGNC:20323|Ensembl:ENSG00000112562|Vega:OTTHUMG00000016050 +64096 GFRA4 HGNC:HGNC:13821|Ensembl:ENSG00000125861|Vega:OTTHUMG00000031748 +64097 EPB41L4A MIM:612141|HGNC:HGNC:13278|Ensembl:ENSG00000129595|Vega:OTTHUMG00000162902 +64098 PARVG MIM:608122|HGNC:HGNC:14654|Ensembl:ENSG00000138964|Vega:OTTHUMG00000150473 +64100 ELSPBP1 MIM:607443|HGNC:HGNC:14417|Ensembl:ENSG00000169393|Vega:OTTHUMG00000183138 +64101 LRRC4 MIM:610486|HGNC:HGNC:15586|Ensembl:ENSG00000128594|Vega:OTTHUMG00000157563 +64102 TNMD MIM:300459|HGNC:HGNC:17757|Ensembl:ENSG00000000005|Vega:OTTHUMG00000022001 +64105 CENPK MIM:611502|HGNC:HGNC:29479|Ensembl:ENSG00000123219|Vega:OTTHUMG00000131227 +64106 NPFFR1 MIM:607448|HGNC:HGNC:17425|Ensembl:ENSG00000148734|Vega:OTTHUMG00000018404 +64108 RTP4 MIM:609350|HGNC:HGNC:23992|Ensembl:ENSG00000136514|Vega:OTTHUMG00000156459 +64109 CRLF2 MIM:300357|MIM:400023|HGNC:HGNC:14281|Ensembl:ENSG00000205755|Vega:OTTHUMG00000067432 +64110 MAGEF1 MIM:609267|HGNC:HGNC:29639|Ensembl:ENSG00000177383|Vega:OTTHUMG00000156712 +64111 NPVF MIM:616984|HGNC:HGNC:13782|Ensembl:ENSG00000105954|Vega:OTTHUMG00000128509 +64112 MOAP1 MIM:609485|HGNC:HGNC:16658|Ensembl:ENSG00000165943|Vega:OTTHUMG00000169184 +64114 TMBIM1 MIM:610364|HGNC:HGNC:23410|Ensembl:ENSG00000135926|Vega:OTTHUMG00000133105 +64115 VSIR MIM:615608|HGNC:HGNC:30085|Ensembl:ENSG00000107738|Vega:OTTHUMG00000018426 +64116 SLC39A8 MIM:608732|HGNC:HGNC:20862|Ensembl:ENSG00000138821|Vega:OTTHUMG00000131120 +64118 DUS1L HGNC:HGNC:30086|Ensembl:ENSG00000169718|Vega:OTTHUMG00000178525 +64121 RRAGC MIM:608267|HGNC:HGNC:19902|Ensembl:ENSG00000116954|Vega:OTTHUMG00000000490 +64122 FN3K MIM:608425|HGNC:HGNC:24822|Ensembl:ENSG00000167363|Vega:OTTHUMG00000177847 +64123 ADGRL4 MIM:616419|HGNC:HGNC:20822|Ensembl:ENSG00000162618|Vega:OTTHUMG00000009738 +64127 NOD2 MIM:605956|HGNC:HGNC:5331|Ensembl:ENSG00000167207|Vega:OTTHUMG00000133171 +64129 TINAGL1 MIM:616064|HGNC:HGNC:19168|Ensembl:ENSG00000142910|Vega:OTTHUMG00000003884 +64130 LIN7B MIM:612331|HGNC:HGNC:17788|Ensembl:ENSG00000104863|Vega:OTTHUMG00000134288 +64131 XYLT1 MIM:608124|HGNC:HGNC:15516|Ensembl:ENSG00000103489|Vega:OTTHUMG00000129975 +64132 XYLT2 MIM:608125|HGNC:HGNC:15517|Ensembl:ENSG00000015532|Vega:OTTHUMG00000162057 +64135 IFIH1 MIM:606951|HGNC:HGNC:18873|Ensembl:ENSG00000115267|Vega:OTTHUMG00000132055 +64137 ABCG4 MIM:607784|HGNC:HGNC:13884|Ensembl:ENSG00000172350|Vega:OTTHUMG00000166169 +64145 RBSN MIM:609511|HGNC:HGNC:20759|Ensembl:ENSG00000131381|Vega:OTTHUMG00000129860 +64146 PDF HGNC:HGNC:30012|Ensembl:ENSG00000258429|Vega:OTTHUMG00000171336 +64147 KIF9 MIM:607910|HGNC:HGNC:16666|Ensembl:ENSG00000088727|Vega:OTTHUMG00000133512 +64149 C17orf75 HGNC:HGNC:30173|Ensembl:ENSG00000108666|Vega:OTTHUMG00000179585 +64150 DIO3OS MIM:608523|HGNC:HGNC:20348 +64151 NCAPG MIM:606280|HGNC:HGNC:24304|Ensembl:ENSG00000109805|Vega:OTTHUMG00000128539 +64167 ERAP2 MIM:609497|HGNC:HGNC:29499|Ensembl:ENSG00000164308|Vega:OTTHUMG00000128718 +64168 NECAB1 HGNC:HGNC:20983|Ensembl:ENSG00000123119|Vega:OTTHUMG00000164009 +64170 CARD9 MIM:607212|HGNC:HGNC:16391|Ensembl:ENSG00000187796|Vega:OTTHUMG00000020925 +64172 OSGEPL1 HGNC:HGNC:23075|Ensembl:ENSG00000128694|Vega:OTTHUMG00000164096 +64174 DPEP2 MIM:609925|HGNC:HGNC:23028|Ensembl:ENSG00000167261|Vega:OTTHUMG00000137542 +64175 P3H1 MIM:610339|HGNC:HGNC:19316|Ensembl:ENSG00000117385|Vega:OTTHUMG00000007525 +64180 DPEP3 MIM:609926|HGNC:HGNC:23029|Ensembl:ENSG00000141096|Vega:OTTHUMG00000137544 +64184 EDDM3B MIM:611582|HGNC:HGNC:19223|Ensembl:ENSG00000181552|Vega:OTTHUMG00000029583 +64207 IRF2BPL MIM:611720|HGNC:HGNC:14282|Ensembl:ENSG00000119669|Vega:OTTHUMG00000171578 +64208 POPDC3 MIM:605824|HGNC:HGNC:17649|Ensembl:ENSG00000132429|Vega:OTTHUMG00000015293 +64210 MMS19 MIM:614777|HGNC:HGNC:13824|Ensembl:ENSG00000155229|Vega:OTTHUMG00000018857 +64211 LHX5 MIM:605992|HGNC:HGNC:14216|Ensembl:ENSG00000089116|Vega:OTTHUMG00000169552 +64215 DNAJC1 MIM:611207|HGNC:HGNC:20090|Ensembl:ENSG00000136770|Vega:OTTHUMG00000017800 +64216 TFB2M MIM:607055|HGNC:HGNC:18559|Ensembl:ENSG00000162851|Vega:OTTHUMG00000040091 +64218 SEMA4A MIM:607292|HGNC:HGNC:10729|Ensembl:ENSG00000196189|Vega:OTTHUMG00000014042 +64219 PJA1 MIM:300420|HGNC:HGNC:16648|Ensembl:ENSG00000181191|Vega:OTTHUMG00000021753 +64220 STRA6 MIM:610745|HGNC:HGNC:30650|Ensembl:ENSG00000137868|Vega:OTTHUMG00000138998 +64221 ROBO3 MIM:608630|HGNC:HGNC:13433|Ensembl:ENSG00000154134|Vega:OTTHUMG00000165934 +64222 TOR3A MIM:607555|HGNC:HGNC:11997|Ensembl:ENSG00000186283|Vega:OTTHUMG00000035077 +64223 MLST8 MIM:612190|HGNC:HGNC:24825|Ensembl:ENSG00000167965|Vega:OTTHUMG00000128827 +64224 HERPUD2 HGNC:HGNC:21915|Ensembl:ENSG00000122557|Vega:OTTHUMG00000128687 +64225 ATL2 MIM:609368|HGNC:HGNC:24047|Ensembl:ENSG00000119787|Vega:OTTHUMG00000102074 +64231 MS4A6A MIM:606548|HGNC:HGNC:13375|Ensembl:ENSG00000110077|Vega:OTTHUMG00000167241 +64232 MS4A5 MIM:606499|HGNC:HGNC:13374|Ensembl:ENSG00000166930|Vega:OTTHUMG00000167613 +64236 PDLIM2 MIM:609722|HGNC:HGNC:13992|Ensembl:ENSG00000120913|Vega:OTTHUMG00000164270 +64239 RSCIS MIM:605463 +64240 ABCG5 MIM:605459|HGNC:HGNC:13886|Ensembl:ENSG00000138075|Vega:OTTHUMG00000128758 +64241 ABCG8 MIM:605460|HGNC:HGNC:13887|Ensembl:ENSG00000143921|Vega:OTTHUMG00000128756 +64282 PAPD5 MIM:605540|HGNC:HGNC:30758|Ensembl:ENSG00000121274|Vega:OTTHUMG00000173452 +64283 ARHGEF28 MIM:612790|HGNC:HGNC:30322|Ensembl:ENSG00000214944|Vega:OTTHUMG00000162454 +64284 RAB17 MIM:602206|HGNC:HGNC:16523|Ensembl:ENSG00000124839|Vega:OTTHUMG00000133299 +64285 RHBDF1 MIM:614403|HGNC:HGNC:20561|Ensembl:ENSG00000007384|Vega:OTTHUMG00000060719 +64288 ZSCAN31 MIM:610794|HGNC:HGNC:14097|Ensembl:ENSG00000235109|Vega:OTTHUMG00000014518 +64318 NOC3L MIM:610769|HGNC:HGNC:24034|Ensembl:ENSG00000173145|Vega:OTTHUMG00000018788 +64319 FBRS MIM:608601|HGNC:HGNC:20442|Ensembl:ENSG00000156860|Vega:OTTHUMG00000132390 +64320 RNF25 MIM:616014|HGNC:HGNC:14662|Ensembl:ENSG00000163481|Vega:OTTHUMG00000133077 +64321 SOX17 MIM:610928|HGNC:HGNC:18122|Ensembl:ENSG00000164736|Vega:OTTHUMG00000164377 +64324 NSD1 MIM:606681|HGNC:HGNC:14234|Ensembl:ENSG00000165671|Vega:OTTHUMG00000130846 +64326 RFWD2 MIM:608067|HGNC:HGNC:17440|Ensembl:ENSG00000143207|Vega:OTTHUMG00000034986 +64327 LMBR1 MIM:605522|HGNC:HGNC:13243|Ensembl:ENSG00000105983|Vega:OTTHUMG00000151510 +64328 XPO4 MIM:611449|HGNC:HGNC:17796|Ensembl:ENSG00000132953|Vega:OTTHUMG00000016528 +64332 NFKBIZ MIM:608004|HGNC:HGNC:29805|Ensembl:ENSG00000144802|Vega:OTTHUMG00000159194 +64333 ARHGAP9 MIM:610576|HGNC:HGNC:14130|Ensembl:ENSG00000123329|Vega:OTTHUMG00000150147 +64342 HS1BP3 MIM:609359|HGNC:HGNC:24979|Ensembl:ENSG00000118960|Vega:OTTHUMG00000122099 +64343 AZI2 MIM:609916|HGNC:HGNC:24002|Ensembl:ENSG00000163512|Vega:OTTHUMG00000130573 +64344 HIF3A MIM:609976|HGNC:HGNC:15825|Ensembl:ENSG00000124440|Vega:OTTHUMG00000141296 +64359 NXN MIM:612895|HGNC:HGNC:18008|Ensembl:ENSG00000167693|Vega:OTTHUMG00000090307 +64374 SIL1 MIM:608005|HGNC:HGNC:24624|Ensembl:ENSG00000120725|Vega:OTTHUMG00000129226 +64375 IKZF4 MIM:606239|HGNC:HGNC:13179|Ensembl:ENSG00000123411|Vega:OTTHUMG00000170132 +64376 IKZF5 MIM:606238|HGNC:HGNC:14283|Ensembl:ENSG00000095574|Vega:OTTHUMG00000019192 +64377 CHST8 MIM:610190|HGNC:HGNC:15993|Ensembl:ENSG00000124302|Vega:OTTHUMG00000180472 +64386 MMP25 MIM:608482|HGNC:HGNC:14246|Ensembl:ENSG00000008516|Vega:OTTHUMG00000177475 +64388 GREM2 MIM:608832|HGNC:HGNC:17655|Ensembl:ENSG00000180875|Vega:OTTHUMG00000039909 +64393 ZMAT3 MIM:606452|HGNC:HGNC:29983|Ensembl:ENSG00000172667|Vega:OTTHUMG00000157290 +64395 GMCL1 HGNC:HGNC:23843|Ensembl:ENSG00000087338|Vega:OTTHUMG00000129643 +64396 GMCL1P1 HGNC:HGNC:19717 +64397 ZNF106 HGNC:HGNC:12886|Ensembl:ENSG00000103994|Vega:OTTHUMG00000173244 +64398 MPP5 MIM:606958|HGNC:HGNC:18669|Ensembl:ENSG00000072415|Vega:OTTHUMG00000171243 +64399 HHIP MIM:606178|HGNC:HGNC:14866|Ensembl:ENSG00000164161|Vega:OTTHUMG00000161428 +64400 AKTIP MIM:608483|HGNC:HGNC:16710|Ensembl:ENSG00000166971|Vega:OTTHUMG00000133199 +64403 CDH24 HGNC:HGNC:14265|Ensembl:ENSG00000139880|Vega:OTTHUMG00000028715 +64405 CDH22 MIM:609920|HGNC:HGNC:13251|Ensembl:ENSG00000149654|Vega:OTTHUMG00000033073 +64407 RGS18 MIM:607192|HGNC:HGNC:14261|Ensembl:ENSG00000150681|Vega:OTTHUMG00000035592 +64409 GALNT17 MIM:615137|HGNC:HGNC:16347|Ensembl:ENSG00000185274|Vega:OTTHUMG00000129783 +64410 KLHL25 HGNC:HGNC:25732|Ensembl:ENSG00000183655|Vega:OTTHUMG00000148672 +64411 ARAP3 MIM:606647|HGNC:HGNC:24097|Ensembl:ENSG00000120318|Vega:OTTHUMG00000129610 +64412 GZF1 MIM:613842|HGNC:HGNC:15808|Ensembl:ENSG00000125812|Vega:OTTHUMG00000032069 +64417 TMEM267 HGNC:HGNC:26139|Ensembl:ENSG00000151881|Vega:OTTHUMG00000131150 +64418 TMEM168 HGNC:HGNC:25826|Ensembl:ENSG00000146802|Vega:OTTHUMG00000155188 +64419 MTMR14 MIM:611089|HGNC:HGNC:26190|Ensembl:ENSG00000163719|Vega:OTTHUMG00000155111 +64420 SUSD1 HGNC:HGNC:25413|Ensembl:ENSG00000106868|Vega:OTTHUMG00000020499 +64421 DCLRE1C MIM:605988|HGNC:HGNC:17642|Ensembl:ENSG00000152457|Vega:OTTHUMG00000017716 +64422 ATG3 MIM:609606|HGNC:HGNC:20962|Ensembl:ENSG00000144848|Vega:OTTHUMG00000159260 +64423 INF2 MIM:610982|HGNC:HGNC:23791|Ensembl:ENSG00000203485|Vega:OTTHUMG00000029811 +64425 POLR1E HGNC:HGNC:17631|Ensembl:ENSG00000137054|Vega:OTTHUMG00000019920 +64426 SUDS3 MIM:608250|HGNC:HGNC:29545|Ensembl:ENSG00000111707|Vega:OTTHUMG00000168884 +64427 TTC31 HGNC:HGNC:25759|Ensembl:ENSG00000115282|Vega:OTTHUMG00000152887 +64428 NARFL MIM:611118|HGNC:HGNC:14179|Ensembl:ENSG00000103245|Vega:OTTHUMG00000122093 +64429 ZDHHC6 HGNC:HGNC:19160|Ensembl:ENSG00000023041|Vega:OTTHUMG00000019062 +64430 PCNX4 HGNC:HGNC:20349|Ensembl:ENSG00000126773|Vega:OTTHUMG00000150361 +64431 ACTR6 HGNC:HGNC:24025|Ensembl:ENSG00000075089|Vega:OTTHUMG00000170245 +64432 MRPS25 MIM:611987|HGNC:HGNC:14511|Ensembl:ENSG00000131368|Vega:OTTHUMG00000129836 +64433 LINC00244 HGNC:HGNC:13245|Ensembl:ENSG00000279418 +64434 NOM1 MIM:611269|HGNC:HGNC:13244|Ensembl:ENSG00000146909|Vega:OTTHUMG00000152639 +64446 DNAI2 MIM:605483|HGNC:HGNC:18744|Ensembl:ENSG00000171595|Vega:OTTHUMG00000178578 +64478 CSMD1 MIM:608397|HGNC:HGNC:14026|Ensembl:ENSG00000183117|Vega:OTTHUMG00000163605 +64493 LINC00235 HGNC:HGNC:14138 +64499 TPSB2 MIM:191081|HGNC:HGNC:14120|Ensembl:ENSG00000197253|Vega:OTTHUMG00000155926 +64506 CPEB1 MIM:607342|HGNC:HGNC:21744|Ensembl:ENSG00000214575|Vega:OTTHUMG00000172877 +64518 TEKT3 MIM:612683|HGNC:HGNC:14293|Ensembl:ENSG00000125409|Vega:OTTHUMG00000058965 +64577 ALDH8A1 MIM:606467|HGNC:HGNC:15471|Ensembl:ENSG00000118514|Vega:OTTHUMG00000015623 +64579 NDST4 MIM:615039|HGNC:HGNC:20779|Ensembl:ENSG00000138653|Vega:OTTHUMG00000132916 +64581 CLEC7A MIM:606264|HGNC:HGNC:14558|Ensembl:ENSG00000172243|Vega:OTTHUMG00000133597 +64582 GPR135 MIM:607970|HGNC:HGNC:19991|Ensembl:ENSG00000181619|Vega:OTTHUMG00000140325 +64585 BOS2 MIM:120502 +64591 TSPY2 HGNC:HGNC:23924|Ensembl:ENSG00000168757|Vega:OTTHUMG00000040957 +64593 RBMY3AP HGNC:HGNC:23286 +64595 TTTY15 HGNC:HGNC:18567|Ensembl:ENSG00000233864 +64596 PSMA6P1 HGNC:HGNC:17460 +64598 MOSPD3 MIM:609125|HGNC:HGNC:25078|Ensembl:ENSG00000106330|Vega:OTTHUMG00000159599 +64599 GIGYF1 MIM:612064|HGNC:HGNC:9126|Ensembl:ENSG00000146830|Vega:OTTHUMG00000157036 +64600 PLA2G2F MIM:616793|HGNC:HGNC:30040|Ensembl:ENSG00000158786|Vega:OTTHUMG00000002704 +64601 VPS16 MIM:608550|HGNC:HGNC:14584|Ensembl:ENSG00000215305|Vega:OTTHUMG00000031714 +64641 EBF2 MIM:609934|HGNC:HGNC:19090|Ensembl:ENSG00000221818|Vega:OTTHUMG00000163838 +64644 GINGF2 MIM:605544|HGNC:HGNC:14252 +64645 MFSD14A HGNC:HGNC:23363|Ensembl:ENSG00000156875|Vega:OTTHUMG00000010755 +64648 SPANXD MIM:300670|MIM:300671|HGNC:HGNC:14332|Ensembl:ENSG00000196406|Vega:OTTHUMG00000022563 +64651 CSRNP1 MIM:606458|HGNC:HGNC:14300|Ensembl:ENSG00000144655|Vega:OTTHUMG00000131293 +64663 SPANXC MIM:300330|HGNC:HGNC:14331|Ensembl:ENSG00000198573|Vega:OTTHUMG00000022556 +64682 ANAPC1 MIM:608473|HGNC:HGNC:19988|Ensembl:ENSG00000153107|Vega:OTTHUMG00000131277 +64689 GORASP1 MIM:606867|HGNC:HGNC:16769|Ensembl:ENSG00000114745|Vega:OTTHUMG00000131292 +64693 CTAGE1 MIM:608856|HGNC:HGNC:24346|Ensembl:ENSG00000212710|Vega:OTTHUMG00000165867 +64695 SLEB3 MIM:605480|HGNC:HGNC:14535 +64699 TMPRSS3 MIM:605511|HGNC:HGNC:11877|Ensembl:ENSG00000160183|Vega:OTTHUMG00000086796 +64708 COPS7B MIM:616010|HGNC:HGNC:16760|Ensembl:ENSG00000144524|Vega:OTTHUMG00000133228 +64710 NUCKS1 MIM:611912|HGNC:HGNC:29923|Ensembl:ENSG00000069275|Vega:OTTHUMG00000035996 +64711 HS3ST6 HGNC:HGNC:14178|Ensembl:ENSG00000162040|Vega:OTTHUMG00000047860 +64714 PDIA2 MIM:608012|HGNC:HGNC:14180|Ensembl:ENSG00000185615|Vega:OTTHUMG00000064891 +64717 TRG-CCC2-2 HGNC:HGNC:14183 +64718 UNKL MIM:617463|HGNC:HGNC:14184|Ensembl:ENSG00000059145|Vega:OTTHUMG00000128553 +64725 RPS3AP2 HGNC:HGNC:14196 +64726 RPS20P2 HGNC:HGNC:14195 +64730 TJP1P1 HGNC:HGNC:14167 +64735 LINC00254 HGNC:HGNC:14160|Ensembl:ENSG00000281219 +64743 WDR13 MIM:300512|HGNC:HGNC:14352|Ensembl:ENSG00000101940|Vega:OTTHUMG00000024119 +64744 SMAP2 MIM:616916|HGNC:HGNC:25082|Ensembl:ENSG00000084070|Vega:OTTHUMG00000007301 +64745 METTL17 MIM:616091|HGNC:HGNC:19280|Ensembl:ENSG00000165792|Vega:OTTHUMG00000029610 +64746 ACBD3 MIM:606809|HGNC:HGNC:15453|Ensembl:ENSG00000182827|Vega:OTTHUMG00000037560 +64747 MFSD1 HGNC:HGNC:25874|Ensembl:ENSG00000118855|Vega:OTTHUMG00000158835 +64748 PLPPR2 HGNC:HGNC:29566|Ensembl:ENSG00000105520|Vega:OTTHUMG00000182023 +64750 SMURF2 MIM:605532|HGNC:HGNC:16809|Ensembl:ENSG00000108854|Vega:OTTHUMG00000179189 +64753 CCDC136 MIM:611902|HGNC:HGNC:22225|Ensembl:ENSG00000128596|Vega:OTTHUMG00000158310 +64754 SMYD3 MIM:608783|HGNC:HGNC:15513|Ensembl:ENSG00000185420|Vega:OTTHUMG00000040508 +64755 C16orf58 HGNC:HGNC:25848|Ensembl:ENSG00000140688|Vega:OTTHUMG00000132466 +64756 ATPAF1 MIM:608917|HGNC:HGNC:18803|Ensembl:ENSG00000123472|Vega:OTTHUMG00000007988 +64757 MARC1 MIM:614126|HGNC:HGNC:26189|Ensembl:ENSG00000186205|Vega:OTTHUMG00000037353 +64759 TNS3 MIM:606825|HGNC:HGNC:21616|Ensembl:ENSG00000136205|Vega:OTTHUMG00000074075 +64760 FAM160B2 HGNC:HGNC:16492|Ensembl:ENSG00000158863|Vega:OTTHUMG00000097088 +64761 PARP12 MIM:612481|HGNC:HGNC:21919|Ensembl:ENSG00000059378|Vega:OTTHUMG00000157315 +64762 GAREM1 HGNC:HGNC:26136|Ensembl:ENSG00000141441|Vega:OTTHUMG00000132273 +64763 ZNF574 HGNC:HGNC:26166|Ensembl:ENSG00000105732|Vega:OTTHUMG00000182751 +64764 CREB3L2 MIM:608834|HGNC:HGNC:23720|Ensembl:ENSG00000182158|Vega:OTTHUMG00000155744 +64766 S100PBP MIM:611889|HGNC:HGNC:25768|Ensembl:ENSG00000116497|Vega:OTTHUMG00000003955 +64768 IPPK HGNC:HGNC:14645|Ensembl:ENSG00000127080|Vega:OTTHUMG00000020231 +64769 MEAF6 MIM:611001|HGNC:HGNC:25674|Ensembl:ENSG00000163875|Vega:OTTHUMG00000004223 +64770 CCDC14 MIM:617147|HGNC:HGNC:25766|Ensembl:ENSG00000175455|Vega:OTTHUMG00000153005 +64771 C6orf106 MIM:612217|HGNC:HGNC:21215|Ensembl:ENSG00000196821|Vega:OTTHUMG00000014553 +64772 ENGASE MIM:611898|HGNC:HGNC:24622|Ensembl:ENSG00000167280|Vega:OTTHUMG00000167714 +64773 PCED1A HGNC:HGNC:16212|Ensembl:ENSG00000132635|Vega:OTTHUMG00000031716 +64776 C11orf1 HGNC:HGNC:1163|Ensembl:ENSG00000137720|Vega:OTTHUMG00000166884 +64777 RMND5B HGNC:HGNC:26181|Ensembl:ENSG00000145916|Vega:OTTHUMG00000130897 +64778 FNDC3B MIM:611909|HGNC:HGNC:24670|Ensembl:ENSG00000075420|Vega:OTTHUMG00000156761 +64779 MTHFSD MIM:616820|HGNC:HGNC:25778|Ensembl:ENSG00000103248|Vega:OTTHUMG00000176480 +64780 MICAL1 MIM:607129|HGNC:HGNC:20619|Ensembl:ENSG00000135596|Vega:OTTHUMG00000015350 +64781 CERK MIM:610307|HGNC:HGNC:19256|Ensembl:ENSG00000100422|Vega:OTTHUMG00000150395 +64782 AEN MIM:610177|HGNC:HGNC:25722|Ensembl:ENSG00000181026|Vega:OTTHUMG00000148681 +64783 RBM15 MIM:606077|HGNC:HGNC:14959|Ensembl:ENSG00000162775|Vega:OTTHUMG00000011284 +64784 CRTC3 MIM:608986|HGNC:HGNC:26148|Ensembl:ENSG00000140577|Vega:OTTHUMG00000172295 +64785 GINS3 MIM:610610|HGNC:HGNC:25851|Ensembl:ENSG00000181938|Vega:OTTHUMG00000133486 +64786 TBC1D15 MIM:612662|HGNC:HGNC:25694|Ensembl:ENSG00000121749|Vega:OTTHUMG00000158553 +64787 EPS8L2 MIM:614988|HGNC:HGNC:21296|Ensembl:ENSG00000177106|Vega:OTTHUMG00000165165 +64788 LMF1 MIM:611761|HGNC:HGNC:14154|Ensembl:ENSG00000103227|Ensembl:ENSG00000260807|Vega:OTTHUMG00000047848 +64789 EXO5 HGNC:HGNC:26115|Ensembl:ENSG00000164002|Vega:OTTHUMG00000007305 +64792 IFT22 HGNC:HGNC:21895|Ensembl:ENSG00000128581|Vega:OTTHUMG00000157136 +64793 CEP85 HGNC:HGNC:25309|Ensembl:ENSG00000130695|Vega:OTTHUMG00000003380 +64794 DDX31 MIM:616533|HGNC:HGNC:16715|Ensembl:ENSG00000125485|Vega:OTTHUMG00000020843 +64795 RMND5A HGNC:HGNC:25850|Ensembl:ENSG00000153561|Vega:OTTHUMG00000130262 +64798 DEPTOR MIM:612974|HGNC:HGNC:22953|Ensembl:ENSG00000155792|Vega:OTTHUMG00000165052 +64799 IQCH MIM:612523|HGNC:HGNC:25721|Ensembl:ENSG00000103599|Vega:OTTHUMG00000133231 +64800 EFCAB6 HGNC:HGNC:24204|Ensembl:ENSG00000186976|Vega:OTTHUMG00000150522 +64801 ARV1 MIM:611647|HGNC:HGNC:29561|Ensembl:ENSG00000173409|Vega:OTTHUMG00000037837 +64802 NMNAT1 MIM:608700|HGNC:HGNC:17877|Ensembl:ENSG00000173614|Vega:OTTHUMG00000001799 +64805 P2RY12 MIM:600515|HGNC:HGNC:18124|Ensembl:ENSG00000169313|Vega:OTTHUMG00000159863 +64806 IL25 MIM:605658|HGNC:HGNC:13765|Ensembl:ENSG00000166090|Vega:OTTHUMG00000028749 +64816 CYP3A43 MIM:606534|HGNC:HGNC:17450|Ensembl:ENSG00000021461|Vega:OTTHUMG00000156498 +64834 ELOVL1 MIM:611813|HGNC:HGNC:14418|Ensembl:ENSG00000066322|Vega:OTTHUMG00000007422 +64837 KLC2 MIM:611729|HGNC:HGNC:20716|Ensembl:ENSG00000174996|Vega:OTTHUMG00000133757 +64838 FNDC4 MIM:611905|HGNC:HGNC:20239|Ensembl:ENSG00000115226|Vega:OTTHUMG00000097787 +64839 FBXL17 MIM:609083|HGNC:HGNC:13615|Ensembl:ENSG00000145743 +64840 PORCN MIM:300651|HGNC:HGNC:17652|Ensembl:ENSG00000102312|Vega:OTTHUMG00000024116 +64841 GNPNAT1 MIM:616510|HGNC:HGNC:19980|Ensembl:ENSG00000100522|Vega:OTTHUMG00000152334 +64843 ISL2 MIM:609481|HGNC:HGNC:18524|Ensembl:ENSG00000159556|Vega:OTTHUMG00000143723 +64844 MARCH7 MIM:613334|HGNC:HGNC:17393|Ensembl:ENSG00000136536|Vega:OTTHUMG00000132029 +64847 SPATA20 MIM:613939|HGNC:HGNC:26125|Ensembl:ENSG00000006282|Vega:OTTHUMG00000162162 +64848 YTHDC2 MIM:616530|HGNC:HGNC:24721|Ensembl:ENSG00000047188|Vega:OTTHUMG00000128837 +64849 SLC13A3 MIM:606411|HGNC:HGNC:14430|Ensembl:ENSG00000158296|Vega:OTTHUMG00000033042 +64850 ETNPPL MIM:614682|HGNC:HGNC:14404|Ensembl:ENSG00000164089|Vega:OTTHUMG00000161036 +64851 AD6 MIM:605526 +64852 TUT1 MIM:610641|HGNC:HGNC:26184|Ensembl:ENSG00000149016|Vega:OTTHUMG00000158564 +64853 AIDA MIM:612375|HGNC:HGNC:25761|Ensembl:ENSG00000186063|Vega:OTTHUMG00000037653 +64854 USP46 MIM:612849|HGNC:HGNC:20075|Ensembl:ENSG00000109189|Vega:OTTHUMG00000160640 +64855 FAM129B MIM:614045|HGNC:HGNC:25282|Ensembl:ENSG00000136830|Vega:OTTHUMG00000020705 +64856 VWA1 MIM:611901|HGNC:HGNC:30910|Ensembl:ENSG00000179403|Vega:OTTHUMG00000002975 +64857 PLEKHG2 MIM:611893|HGNC:HGNC:29515|Ensembl:ENSG00000090924|Vega:OTTHUMG00000152570 +64858 DCLRE1B MIM:609683|HGNC:HGNC:17641|Ensembl:ENSG00000118655|Vega:OTTHUMG00000011937 +64859 NABP1 MIM:612103|HGNC:HGNC:26232|Ensembl:ENSG00000173559|Vega:OTTHUMG00000132720 +64860 ARMCX5 HGNC:HGNC:25772|Ensembl:ENSG00000125962|Vega:OTTHUMG00000022062 +64863 METTL4 HGNC:HGNC:24726|Ensembl:ENSG00000101574|Vega:OTTHUMG00000131482 +64864 RFX7 MIM:612660|HGNC:HGNC:25777|Ensembl:ENSG00000181827|Vega:OTTHUMG00000172508 +64866 CDCP1 MIM:611735|HGNC:HGNC:24357|Ensembl:ENSG00000163814|Vega:OTTHUMG00000133090 +64881 PCDH20 MIM:614449|HGNC:HGNC:14257|Ensembl:ENSG00000197991|Ensembl:ENSG00000280165|Vega:OTTHUMG00000017012|Vega:OTTHUMG00000189120 +64895 PAPOLG MIM:616865|HGNC:HGNC:14982|Ensembl:ENSG00000115421|Vega:OTTHUMG00000129419 +64897 C12orf43 HGNC:HGNC:25719|Ensembl:ENSG00000157895|Vega:OTTHUMG00000169150 +64900 LPIN3 MIM:605520|HGNC:HGNC:14451|Ensembl:ENSG00000132793|Vega:OTTHUMG00000033056 +64901 RANBP17 MIM:606141|HGNC:HGNC:14428|Ensembl:ENSG00000204764|Vega:OTTHUMG00000163203 +64902 AGXT2 MIM:612471|HGNC:HGNC:14412|Ensembl:ENSG00000113492|Vega:OTTHUMG00000090788 +64919 BCL11B MIM:606558|HGNC:HGNC:13222|Ensembl:ENSG00000127152|Vega:OTTHUMG00000028967 +64921 CASD1 MIM:611686|HGNC:HGNC:16014|Ensembl:ENSG00000127995|Vega:OTTHUMG00000023356 +64922 LRRC19 HGNC:HGNC:23379|Ensembl:ENSG00000184434|Vega:OTTHUMG00000019710 +64924 SLC30A5 MIM:607819|HGNC:HGNC:19089|Ensembl:ENSG00000145740|Vega:OTTHUMG00000131253 +64925 CCDC71 HGNC:HGNC:25760|Ensembl:ENSG00000177352|Vega:OTTHUMG00000156815 +64926 RASAL3 MIM:616561|HGNC:HGNC:26129|Ensembl:ENSG00000105122|Vega:OTTHUMG00000182450 +64927 TTC23 HGNC:HGNC:25730|Ensembl:ENSG00000103852|Vega:OTTHUMG00000147344 +64928 MRPL14 MIM:611827|HGNC:HGNC:14279|Ensembl:ENSG00000180992|Vega:OTTHUMG00000014756 +64939 SMNP - +64940 STAG3L4 HGNC:HGNC:33887|Ensembl:ENSG00000106610 +64943 NT5DC2 HGNC:HGNC:25717|Ensembl:ENSG00000168268|Vega:OTTHUMG00000158626 +64946 CENPH MIM:605607|HGNC:HGNC:17268|Ensembl:ENSG00000153044|Vega:OTTHUMG00000097816 +64949 MRPS26 MIM:611988|HGNC:HGNC:14045|Ensembl:ENSG00000125901|Vega:OTTHUMG00000031721 +64951 MRPS24 MIM:611986|HGNC:HGNC:14510|Ensembl:ENSG00000062582|Vega:OTTHUMG00000023175 +64960 MRPS15 MIM:611979|HGNC:HGNC:14504|Ensembl:ENSG00000116898|Vega:OTTHUMG00000008042 +64963 MRPS11 MIM:611977|HGNC:HGNC:14050|Ensembl:ENSG00000181991|Vega:OTTHUMG00000148678 +64965 MRPS9 MIM:611975|HGNC:HGNC:14501|Ensembl:ENSG00000135972|Vega:OTTHUMG00000130807 +64968 MRPS6 MIM:611973|HGNC:HGNC:14051|Ensembl:ENSG00000243927|Vega:OTTHUMG00000065820 +64969 MRPS5 MIM:611972|HGNC:HGNC:14498|Ensembl:ENSG00000144029|Vega:OTTHUMG00000130394 +64975 MRPL41 MIM:611846|HGNC:HGNC:14492|Ensembl:ENSG00000182154|Vega:OTTHUMG00000020987 +64976 MRPL40 MIM:605089|HGNC:HGNC:14491|Ensembl:ENSG00000185608|Vega:OTTHUMG00000150136 +64978 MRPL38 MIM:611844|HGNC:HGNC:14033|Ensembl:ENSG00000204316|Vega:OTTHUMG00000152977 +64979 MRPL36 MIM:611842|HGNC:HGNC:14490|Ensembl:ENSG00000171421|Vega:OTTHUMG00000090373 +64981 MRPL34 MIM:611840|HGNC:HGNC:14488|Ensembl:ENSG00000130312|Vega:OTTHUMG00000182764 +64983 MRPL32 MIM:611839|HGNC:HGNC:14035|Ensembl:ENSG00000106591|Vega:OTTHUMG00000155180 +65003 MRPL11 MIM:611826|HGNC:HGNC:14042|Ensembl:ENSG00000174547|Vega:OTTHUMG00000167097 +65005 MRPL9 MIM:611824|HGNC:HGNC:14277|Ensembl:ENSG00000143436|Vega:OTTHUMG00000013063 +65008 MRPL1 MIM:611821|HGNC:HGNC:14275|Ensembl:ENSG00000169288|Vega:OTTHUMG00000130200 +65009 NDRG4 MIM:614463|HGNC:HGNC:14466|Ensembl:ENSG00000103034|Vega:OTTHUMG00000133485 +65010 SLC26A6 MIM:610068|HGNC:HGNC:14472|Ensembl:ENSG00000225697|Vega:OTTHUMG00000186381 +65012 SLC26A10 HGNC:HGNC:14470|Ensembl:ENSG00000135502|Vega:OTTHUMG00000128505 +65014 CMD1K MIM:605582|HGNC:HGNC:14541 +65018 PINK1 MIM:608309|HGNC:HGNC:14581|Ensembl:ENSG00000158828|Vega:OTTHUMG00000002841 +65055 REEP1 MIM:609139|HGNC:HGNC:25786|Ensembl:ENSG00000068615|Vega:OTTHUMG00000130205 +65056 GPBP1 MIM:608412|HGNC:HGNC:29520|Ensembl:ENSG00000062194|Vega:OTTHUMG00000162321 +65057 ACD MIM:609377|HGNC:HGNC:25070|Ensembl:ENSG00000102977|Vega:OTTHUMG00000137547 +65059 RAPH1 MIM:609035|HGNC:HGNC:14436|Ensembl:ENSG00000173166|Vega:OTTHUMG00000132876 +65061 CDK15 MIM:616147|HGNC:HGNC:14434|Ensembl:ENSG00000138395|Vega:OTTHUMG00000132838 +65062 TMEM237 MIM:614423|HGNC:HGNC:14432|Ensembl:ENSG00000155755|Vega:OTTHUMG00000154526 +65065 NBEAL1 MIM:609816|HGNC:HGNC:20681|Ensembl:ENSG00000144426|Vega:OTTHUMG00000154129 +65072 CFLAR-AS1 HGNC:HGNC:14437|Ensembl:ENSG00000226312 +65076 AOMS1 MIM:605552 +65077 AOMS2 MIM:605572 +65078 RTN4R MIM:605566|HGNC:HGNC:18601|Ensembl:ENSG00000040608|Vega:OTTHUMG00000150572 +65080 MRPL44 MIM:611849|HGNC:HGNC:16650|Ensembl:ENSG00000135900|Vega:OTTHUMG00000133164 +65082 VPS33A MIM:610034|HGNC:HGNC:18179|Ensembl:ENSG00000139719|Ensembl:ENSG00000256861|Vega:OTTHUMG00000168918|Vega:OTTHUMG00000168920 +65083 NOL6 MIM:611532|HGNC:HGNC:19910|Ensembl:ENSG00000165271|Vega:OTTHUMG00000000394 +65084 TMEM135 MIM:616360|HGNC:HGNC:26167|Ensembl:ENSG00000166575|Vega:OTTHUMG00000167248 +65094 JMJD4 HGNC:HGNC:25724|Ensembl:ENSG00000081692|Vega:OTTHUMG00000037698 +65095 KRI1 HGNC:HGNC:25769|Ensembl:ENSG00000129347|Vega:OTTHUMG00000150343 +65108 MARCKSL1 MIM:602940|HGNC:HGNC:7142|Ensembl:ENSG00000175130|Vega:OTTHUMG00000007589 +65109 UPF3B MIM:300298|HGNC:HGNC:20439|Ensembl:ENSG00000125351|Vega:OTTHUMG00000022282 +65110 UPF3A MIM:605530|HGNC:HGNC:20332|Ensembl:ENSG00000169062|Vega:OTTHUMG00000017403 +65117 RSRC2 HGNC:HGNC:30559|Ensembl:ENSG00000111011|Vega:OTTHUMG00000167572 +65121 PRAMEF1 HGNC:HGNC:28840|Ensembl:ENSG00000116721|Vega:OTTHUMG00000001928 +65122 PRAMEF2 HGNC:HGNC:28841|Ensembl:ENSG00000120952|Vega:OTTHUMG00000001986 +65123 INTS3 MIM:611347|HGNC:HGNC:26153|Ensembl:ENSG00000143624|Vega:OTTHUMG00000037089 +65124 SOWAHC HGNC:HGNC:26149|Ensembl:ENSG00000198142|Vega:OTTHUMG00000153219 +65125 WNK1 MIM:605232|HGNC:HGNC:14540|Ensembl:ENSG00000060237|Vega:OTTHUMG00000090321 +65211 FRTS1 MIM:134600 +65217 PCDH15 MIM:605514|HGNC:HGNC:14674|Ensembl:ENSG00000150275|Vega:OTTHUMG00000018259 +65220 NADK MIM:611616|HGNC:HGNC:29831|Ensembl:ENSG00000008130|Vega:OTTHUMG00000000942 +65243 ZFP69B HGNC:HGNC:28053|Ensembl:ENSG00000187801|Vega:OTTHUMG00000007302 +65244 SPATS2 MIM:611667|HGNC:HGNC:18650|Ensembl:ENSG00000123352|Vega:OTTHUMG00000169419 +65245 PSORS7 MIM:605606|HGNC:HGNC:14207 +65249 ZSWIM4 HGNC:HGNC:25704|Ensembl:ENSG00000132003|Vega:OTTHUMG00000181752 +65250 C5orf42 MIM:614571|HGNC:HGNC:25801|Ensembl:ENSG00000197603|Vega:OTTHUMG00000160492 +65251 ZNF649 MIM:611903|HGNC:HGNC:25741|Ensembl:ENSG00000198093|Vega:OTTHUMG00000182423 +65258 MPPE1 MIM:611900|HGNC:HGNC:15988|Ensembl:ENSG00000154889|Vega:OTTHUMG00000131661 +65260 COA7 MIM:615623|HGNC:HGNC:25716|Ensembl:ENSG00000162377|Vega:OTTHUMG00000008505 +65263 PYCR3 MIM:616408|HGNC:HGNC:25846|Ensembl:ENSG00000104524|Vega:OTTHUMG00000157010 +65264 UBE2Z MIM:611362|HGNC:HGNC:25847|Ensembl:ENSG00000159202|Vega:OTTHUMG00000150521 +65265 C8orf33 HGNC:HGNC:26104|Ensembl:ENSG00000182307|Vega:OTTHUMG00000165256 +65266 WNK4 MIM:601844|HGNC:HGNC:14544|Ensembl:ENSG00000126562|Vega:OTTHUMG00000180650 +65267 WNK3 MIM:300358|HGNC:HGNC:14543|Ensembl:ENSG00000196632|Vega:OTTHUMG00000021626 +65268 WNK2 MIM:606249|HGNC:HGNC:14542|Ensembl:ENSG00000165238|Vega:OTTHUMG00000020247 +65944 OR2B8P HGNC:HGNC:13968 +65975 STK33 MIM:607670|HGNC:HGNC:14568|Ensembl:ENSG00000130413|Vega:OTTHUMG00000140275 +65977 PLEKHA3 MIM:607774|HGNC:HGNC:14338|Ensembl:ENSG00000116095|Vega:OTTHUMG00000154446 +65978 IGSF6-DREV1 - +65979 PHACTR4 MIM:608726|HGNC:HGNC:25793|Ensembl:ENSG00000204138|Vega:OTTHUMG00000003541 +65980 BRD9 HGNC:HGNC:25818|Ensembl:ENSG00000028310|Vega:OTTHUMG00000159258 +65981 CAPRIN2 MIM:610375|HGNC:HGNC:21259|Ensembl:ENSG00000110888|Vega:OTTHUMG00000169185 +65982 ZSCAN18 HGNC:HGNC:21037|Ensembl:ENSG00000121413|Vega:OTTHUMG00000183451 +65983 GRAMD2B HGNC:HGNC:24911|Ensembl:ENSG00000155324|Vega:OTTHUMG00000128943 +65985 AACS MIM:614364|HGNC:HGNC:21298|Ensembl:ENSG00000081760|Vega:OTTHUMG00000168550 +65986 ZBTB10 HGNC:HGNC:30953|Ensembl:ENSG00000205189|Vega:OTTHUMG00000155016 +65987 KCTD14 HGNC:HGNC:23295|Ensembl:ENSG00000151364|Vega:OTTHUMG00000150224 +65988 ZNF747 HGNC:HGNC:28350|Ensembl:ENSG00000169955|Ensembl:ENSG00000261459|Vega:OTTHUMG00000132401|Vega:OTTHUMG00000176944 +65989 DLK2 HGNC:HGNC:21113|Ensembl:ENSG00000171462|Vega:OTTHUMG00000014735 +65990 FAM173A HGNC:HGNC:14152|Ensembl:ENSG00000103254|Vega:OTTHUMG00000121177 +65991 FUNDC2 HGNC:HGNC:24925|Ensembl:ENSG00000165775|Vega:OTTHUMG00000013504 +65992 DDRGK1 MIM:616177|HGNC:HGNC:16110|Ensembl:ENSG00000198171|Vega:OTTHUMG00000031732 +65993 MRPS34 MIM:611994|HGNC:HGNC:16618|Ensembl:ENSG00000074071|Vega:OTTHUMG00000128636 +65996 CENPBD1P1 HGNC:HGNC:28421|Ensembl:ENSG00000213753 +65997 RASL11B MIM:612404|HGNC:HGNC:23804|Ensembl:ENSG00000128045|Vega:OTTHUMG00000102097 +65998 C11orf95 MIM:615699|HGNC:HGNC:28449|Ensembl:ENSG00000188070|Vega:OTTHUMG00000167840 +65999 LRRC61 HGNC:HGNC:21704|Ensembl:ENSG00000127399|Vega:OTTHUMG00000158326 +66000 TMEM108 MIM:617361|HGNC:HGNC:28451|Ensembl:ENSG00000144868|Vega:OTTHUMG00000159685 +66001 MLVI4 - +66002 CYP4F12 MIM:611485|HGNC:HGNC:18857|Ensembl:ENSG00000186204|Vega:OTTHUMG00000164477 +66004 LYNX1 MIM:606110|HGNC:HGNC:29604|Ensembl:ENSG00000180155|Ensembl:ENSG00000283992|Ensembl:ENSG00000284505|Vega:OTTHUMG00000164694 +66005 CHID1 MIM:615692|HGNC:HGNC:28474|Ensembl:ENSG00000177830|Vega:OTTHUMG00000133314 +66008 TRAK2 MIM:607334|HGNC:HGNC:13206|Ensembl:ENSG00000115993|Vega:OTTHUMG00000132822 +66035 SLC2A11 MIM:610367|HGNC:HGNC:14239|Ensembl:ENSG00000133460|Vega:OTTHUMG00000166469 +66036 MTMR9 MIM:606260|HGNC:HGNC:14596|Ensembl:ENSG00000104643|Vega:OTTHUMG00000090647 +66037 BOLL MIM:606165|HGNC:HGNC:14273|Ensembl:ENSG00000152430|Vega:OTTHUMG00000132747 +78986 DUSP26 HGNC:HGNC:28161|Ensembl:ENSG00000133878|Vega:OTTHUMG00000163961 +78987 CRELD1 MIM:607170|HGNC:HGNC:14630|Ensembl:ENSG00000163703|Vega:OTTHUMG00000128653 +78988 MRPL57 MIM:611997|HGNC:HGNC:14514|Ensembl:ENSG00000173141|Vega:OTTHUMG00000016532 +78989 COLEC11 MIM:612502|HGNC:HGNC:17213|Ensembl:ENSG00000118004|Vega:OTTHUMG00000090304 +78990 OTUB2 MIM:608338|HGNC:HGNC:20351|Ensembl:ENSG00000089723|Vega:OTTHUMG00000171300 +78991 PCYOX1L HGNC:HGNC:28477|Ensembl:ENSG00000145882|Vega:OTTHUMG00000130052 +78992 YIPF2 MIM:617522|HGNC:HGNC:28476|Ensembl:ENSG00000130733|Vega:OTTHUMG00000180796 +78994 PRR14 MIM:617423|HGNC:HGNC:28458|Ensembl:ENSG00000156858|Vega:OTTHUMG00000132414 +78995 C17orf53 HGNC:HGNC:28460|Ensembl:ENSG00000125319|Vega:OTTHUMG00000181808 +78996 C7orf49 MIM:616980|HGNC:HGNC:22432|Ensembl:ENSG00000122783|Vega:OTTHUMG00000155447 +78997 GDAP1L1 HGNC:HGNC:4213|Ensembl:ENSG00000124194|Vega:OTTHUMG00000032530 +78998 RHPN1-AS1 HGNC:HGNC:28457|Ensembl:ENSG00000254389 +78999 LRFN4 MIM:612810|HGNC:HGNC:28456|Ensembl:ENSG00000173621|Vega:OTTHUMG00000167100 +79000 AUNIP HGNC:HGNC:28363|Ensembl:ENSG00000127423|Vega:OTTHUMG00000007372 +79001 VKORC1 MIM:608547|HGNC:HGNC:23663|Ensembl:ENSG00000167397|Vega:OTTHUMG00000047408 +79002 TRIR HGNC:HGNC:28424|Ensembl:ENSG00000123144|Vega:OTTHUMG00000180347 +79003 MIS12 MIM:609178|HGNC:HGNC:24967|Ensembl:ENSG00000167842|Vega:OTTHUMG00000102042 +79004 CUEDC2 MIM:614142|HGNC:HGNC:28352|Ensembl:ENSG00000107874|Vega:OTTHUMG00000018958 +79005 SCNM1 MIM:608095|HGNC:HGNC:23136|Ensembl:ENSG00000163156|Vega:OTTHUMG00000012258 +79006 METRN MIM:610998|HGNC:HGNC:14151|Ensembl:ENSG00000103260|Vega:OTTHUMG00000047851 +79007 DBNDD1 HGNC:HGNC:28455|Ensembl:ENSG00000003249|Vega:OTTHUMG00000138984 +79008 SLX1B MIM:615823|HGNC:HGNC:28748|Ensembl:ENSG00000181625|Vega:OTTHUMG00000132110 +79009 DDX50 MIM:610373|HGNC:HGNC:17906|Ensembl:ENSG00000107625|Vega:OTTHUMG00000018362 +79012 CAMKV MIM:614993|HGNC:HGNC:28788|Ensembl:ENSG00000164076|Vega:OTTHUMG00000158288 +79015 LINC01260 HGNC:HGNC:49900|Ensembl:ENSG00000283440 +79016 DDA1 HGNC:HGNC:28360|Ensembl:ENSG00000130311|Vega:OTTHUMG00000182765 +79017 GGCT MIM:137170|HGNC:HGNC:21705|Ensembl:ENSG00000006625|Vega:OTTHUMG00000128593 +79018 GID4 HGNC:HGNC:28453|Ensembl:ENSG00000141034|Vega:OTTHUMG00000059398 +79019 CENPM MIM:610152|HGNC:HGNC:18352|Ensembl:ENSG00000100162|Vega:OTTHUMG00000151277 +79020 C7orf25 HGNC:HGNC:21703|Ensembl:ENSG00000136197|Vega:OTTHUMG00000128869 +79022 TMEM106C HGNC:HGNC:28775|Ensembl:ENSG00000134291|Vega:OTTHUMG00000169892 +79023 NUP37 MIM:609264|HGNC:HGNC:29929|Ensembl:ENSG00000075188|Vega:OTTHUMG00000170478 +79024 SMIM2 HGNC:HGNC:28776|Ensembl:ENSG00000139656|Vega:OTTHUMG00000016831 +79025 FNDC11 HGNC:HGNC:28764|Ensembl:ENSG00000125531|Vega:OTTHUMG00000032980 +79026 AHNAK MIM:103390|HGNC:HGNC:347|Ensembl:ENSG00000124942|Vega:OTTHUMG00000167558 +79027 ZNF655 HGNC:HGNC:30899|Ensembl:ENSG00000197343|Vega:OTTHUMG00000185968 +79029 SPATA5L1 HGNC:HGNC:28762|Ensembl:ENSG00000171763|Vega:OTTHUMG00000131425 +79031 PDCL3 MIM:611678|HGNC:HGNC:28860|Ensembl:ENSG00000115539|Vega:OTTHUMG00000153141 +79033 ERI3 MIM:609917|HGNC:HGNC:17276|Ensembl:ENSG00000117419|Vega:OTTHUMG00000007637 +79034 C7orf26 HGNC:HGNC:21702|Ensembl:ENSG00000146576|Vega:OTTHUMG00000125517 +79035 NABP2 MIM:612104|HGNC:HGNC:28412|Ensembl:ENSG00000139579|Vega:OTTHUMG00000152527 +79036 KXD1 MIM:615178|HGNC:HGNC:28420|Ensembl:ENSG00000105700|Vega:OTTHUMG00000183107 +79037 PVRIG MIM:617012|HGNC:HGNC:32190|Ensembl:ENSG00000213413|Vega:OTTHUMG00000156798 +79038 ZFYVE21 MIM:613504|HGNC:HGNC:20760|Ensembl:ENSG00000100711|Vega:OTTHUMG00000171651 +79039 DDX54 MIM:611665|HGNC:HGNC:20084|Ensembl:ENSG00000123064|Vega:OTTHUMG00000169676 +79041 TMEM38A MIM:611235|HGNC:HGNC:28462|Ensembl:ENSG00000072954|Vega:OTTHUMG00000182639 +79042 TSEN34 MIM:608754|HGNC:HGNC:15506|Ensembl:ENSG00000170892|Vega:OTTHUMG00000066515 +79047 KCTD15 MIM:615240|HGNC:HGNC:23297|Ensembl:ENSG00000153885|Vega:OTTHUMG00000180475 +79048 SECISBP2 MIM:607693|HGNC:HGNC:30972|Ensembl:ENSG00000187742|Vega:OTTHUMG00000020182 +79050 NOC4L MIM:612819|HGNC:HGNC:28461|Ensembl:ENSG00000184967|Vega:OTTHUMG00000168260 +79051 RPY MIM:400004 +79052 PTCPRN MIM:605642 +79053 ALG8 MIM:608103|HGNC:HGNC:23161|Ensembl:ENSG00000159063|Vega:OTTHUMG00000166594 +79054 TRPM8 MIM:606678|HGNC:HGNC:17961|Ensembl:ENSG00000144481|Vega:OTTHUMG00000059129 +79055 PSMA2P3 HGNC:HGNC:43834 +79056 PRRG4 MIM:611690|HGNC:HGNC:30799|Ensembl:ENSG00000135378|Vega:OTTHUMG00000166219 +79057 PRRG3 MIM:300685|HGNC:HGNC:30798|Ensembl:ENSG00000130032|Vega:OTTHUMG00000024170 +79058 ASPSCR1 MIM:606236|HGNC:HGNC:13825|Ensembl:ENSG00000169696|Vega:OTTHUMG00000178438 +79064 TMEM223 HGNC:HGNC:28464|Ensembl:ENSG00000168569|Vega:OTTHUMG00000167693 +79065 ATG9A MIM:612204|HGNC:HGNC:22408|Ensembl:ENSG00000198925|Vega:OTTHUMG00000154557 +79066 METTL16 HGNC:HGNC:28484|Ensembl:ENSG00000127804|Vega:OTTHUMG00000177564 +79068 FTO MIM:610966|HGNC:HGNC:24678|Ensembl:ENSG00000140718|Vega:OTTHUMG00000158780 +79070 KDELC1 MIM:611613|HGNC:HGNC:19350|Ensembl:ENSG00000134901|Vega:OTTHUMG00000017307 +79071 ELOVL6 MIM:611546|HGNC:HGNC:15829|Ensembl:ENSG00000170522|Vega:OTTHUMG00000132547 +79072 FASTKD3 MIM:617530|HGNC:HGNC:28758|Ensembl:ENSG00000124279|Vega:OTTHUMG00000131029 +79073 TMEM109 HGNC:HGNC:28771|Ensembl:ENSG00000110108|Vega:OTTHUMG00000167801 +79074 C2orf49 HGNC:HGNC:28772|Ensembl:ENSG00000135974|Vega:OTTHUMG00000130808 +79075 DSCC1 MIM:613203|HGNC:HGNC:24453|Ensembl:ENSG00000136982|Vega:OTTHUMG00000165010 +79077 DCTPP1 MIM:615840|HGNC:HGNC:28777|Ensembl:ENSG00000179958|Vega:OTTHUMG00000132416 +79078 C1orf50 HGNC:HGNC:28795|Ensembl:ENSG00000164008|Vega:OTTHUMG00000191873 +79080 CCDC86 MIM:611293|HGNC:HGNC:28359|Ensembl:ENSG00000110104|Vega:OTTHUMG00000167706 +79081 LBHD1 HGNC:HGNC:28351|Ensembl:ENSG00000162194|Vega:OTTHUMG00000187541 +79083 MLPH MIM:606526|HGNC:HGNC:29643|Ensembl:ENSG00000115648|Vega:OTTHUMG00000133298 +79084 WDR77 MIM:611734|HGNC:HGNC:29652|Ensembl:ENSG00000116455|Vega:OTTHUMG00000011748 +79085 SLC25A23 MIM:608746|HGNC:HGNC:19375|Ensembl:ENSG00000125648|Vega:OTTHUMG00000180852 +79086 SMIM7 HGNC:HGNC:28419|Ensembl:ENSG00000214046|Ensembl:ENSG00000268790|Vega:OTTHUMG00000149895|Vega:OTTHUMG00000182632 +79087 ALG12 MIM:607144|HGNC:HGNC:19358|Ensembl:ENSG00000182858|Vega:OTTHUMG00000150289 +79088 ZNF426 HGNC:HGNC:20725|Ensembl:ENSG00000130818|Vega:OTTHUMG00000180132 +79089 TMUB2 HGNC:HGNC:28459|Ensembl:ENSG00000168591|Vega:OTTHUMG00000181811 +79090 TRAPPC6A MIM:610396|HGNC:HGNC:23069|Ensembl:ENSG00000007255|Vega:OTTHUMG00000181775 +79091 METTL22 MIM:615261|HGNC:HGNC:28368|Ensembl:ENSG00000067365|Vega:OTTHUMG00000129694 +79092 CARD14 MIM:607211|HGNC:HGNC:16446|Ensembl:ENSG00000141527|Vega:OTTHUMG00000177549 +79094 CHAC1 MIM:614587|HGNC:HGNC:28680|Ensembl:ENSG00000128965|Vega:OTTHUMG00000130208 +79095 C9orf16 HGNC:HGNC:17823|Ensembl:ENSG00000171159|Vega:OTTHUMG00000020731 +79096 C11orf49 HGNC:HGNC:28720|Ensembl:ENSG00000149179|Vega:OTTHUMG00000166725 +79097 TRIM48 HGNC:HGNC:19021|Ensembl:ENSG00000150244|Vega:OTTHUMG00000157011 +79098 C1orf116 MIM:611680|HGNC:HGNC:28667|Ensembl:ENSG00000182795|Vega:OTTHUMG00000036580 +79100 LINC00626 HGNC:HGNC:44257|Ensembl:ENSG00000225826 +79101 TAF1D MIM:612823|HGNC:HGNC:28759|Ensembl:ENSG00000166012|Vega:OTTHUMG00000167451 +79102 RNF26 MIM:606130|HGNC:HGNC:14646|Ensembl:ENSG00000173456|Vega:OTTHUMG00000166171 +79104 MEG8 MIM:613648|HGNC:HGNC:14574|Ensembl:ENSG00000225746 +79109 MAPKAP1 MIM:610558|HGNC:HGNC:18752|Ensembl:ENSG00000119487|Vega:OTTHUMG00000020683 +79132 DHX58 MIM:608588|HGNC:HGNC:29517|Ensembl:ENSG00000108771|Vega:OTTHUMG00000133493 +79133 NDUFAF5 MIM:612360|HGNC:HGNC:15899|Ensembl:ENSG00000101247|Vega:OTTHUMG00000031909 +79134 TMEM185B HGNC:HGNC:18896|Ensembl:ENSG00000226479|Vega:OTTHUMG00000154402 +79135 APOO MIM:300753|HGNC:HGNC:28727|Ensembl:ENSG00000184831|Vega:OTTHUMG00000021259 +79136 LY6G6E MIM:610437|HGNC:HGNC:13934 +79137 RETREG2 HGNC:HGNC:28450|Ensembl:ENSG00000144567|Vega:OTTHUMG00000154577 +79139 DERL1 MIM:608813|HGNC:HGNC:28454|Ensembl:ENSG00000136986|Vega:OTTHUMG00000165080 +79140 CCDC28B MIM:610162|HGNC:HGNC:28163|Ensembl:ENSG00000160050|Vega:OTTHUMG00000005738 +79142 PHF23 MIM:612910|HGNC:HGNC:28428|Ensembl:ENSG00000040633|Vega:OTTHUMG00000177972 +79143 MBOAT7 MIM:606048|HGNC:HGNC:15505|Ensembl:ENSG00000125505|Vega:OTTHUMG00000066516 +79144 PPDPF HGNC:HGNC:16142|Ensembl:ENSG00000125534|Vega:OTTHUMG00000032978 +79145 CHCHD7 MIM:611238|HGNC:HGNC:28314|Ensembl:ENSG00000170791|Vega:OTTHUMG00000074081 +79147 FKRP MIM:606596|HGNC:HGNC:17997|Ensembl:ENSG00000181027|Vega:OTTHUMG00000183177 +79148 MMP28 MIM:608417|HGNC:HGNC:14366|Ensembl:ENSG00000271447|Vega:OTTHUMG00000188387 +79149 ZSCAN5A HGNC:HGNC:23710|Ensembl:ENSG00000131848|Vega:OTTHUMG00000181883 +79150 MGC4859 - +79152 FA2H MIM:611026|HGNC:HGNC:21197|Ensembl:ENSG00000103089|Vega:OTTHUMG00000137603 +79153 GDPD3 MIM:616318|HGNC:HGNC:28638|Ensembl:ENSG00000102886|Vega:OTTHUMG00000132106 +79154 DHRS11 MIM:616159|HGNC:HGNC:28639|Ensembl:ENSG00000278535|Vega:OTTHUMG00000188442 +79155 TNIP2 MIM:610669|HGNC:HGNC:19118|Ensembl:ENSG00000168884|Vega:OTTHUMG00000090267 +79156 PLEKHF1 MIM:615200|HGNC:HGNC:20764|Ensembl:ENSG00000166289|Vega:OTTHUMG00000182097 +79157 MFSD11 HGNC:HGNC:25458|Ensembl:ENSG00000092931|Vega:OTTHUMG00000180484 +79158 GNPTAB MIM:607840|HGNC:HGNC:29670|Ensembl:ENSG00000111670|Vega:OTTHUMG00000170444 +79159 NOL12 HGNC:HGNC:28585|Ensembl:ENSG00000100101|Ensembl:ENSG00000273899|Vega:OTTHUMG00000150660|Vega:OTTHUMG00000188619 +79160 LINC01711 HGNC:HGNC:28663|Ensembl:ENSG00000268941 +79161 TMEM243 MIM:616993|HGNC:HGNC:21707|Ensembl:ENSG00000135185|Vega:OTTHUMG00000130823 +79165 LENG1 HGNC:HGNC:15502|Ensembl:ENSG00000105617|Vega:OTTHUMG00000066486 +79166 LILRP2 HGNC:HGNC:15497|Ensembl:ENSG00000170858 +79167 LILRP1 HGNC:HGNC:15496 +79168 LILRA6 HGNC:HGNC:15495|Ensembl:ENSG00000244482|Vega:OTTHUMG00000066635 +79169 C1orf35 HGNC:HGNC:19032|Ensembl:ENSG00000143793|Vega:OTTHUMG00000037793 +79170 PRR15L HGNC:HGNC:28149|Ensembl:ENSG00000167183|Vega:OTTHUMG00000178297 +79171 RBM42 MIM:613232|HGNC:HGNC:28117|Ensembl:ENSG00000126254|Vega:OTTHUMG00000182063 +79172 CENPO MIM:611504|HGNC:HGNC:28152|Ensembl:ENSG00000138092|Vega:OTTHUMG00000125525 +79173 C19orf57 HGNC:HGNC:28153|Ensembl:ENSG00000132016|Vega:OTTHUMG00000181851 +79174 CRELD2 MIM:607171|HGNC:HGNC:28150|Ensembl:ENSG00000184164|Vega:OTTHUMG00000150292 +79175 ZNF343 HGNC:HGNC:16017|Ensembl:ENSG00000088876|Vega:OTTHUMG00000031701 +79176 FBXL15 MIM:610287|HGNC:HGNC:28155|Ensembl:ENSG00000107872|Vega:OTTHUMG00000018957 +79177 ZNF576 HGNC:HGNC:28357|Ensembl:ENSG00000124444|Vega:OTTHUMG00000165479 +79178 THTPA MIM:611612|HGNC:HGNC:18987|Ensembl:ENSG00000259431|Vega:OTTHUMG00000172558 +79179 FHII MIM:605635 +79180 EFHD2 MIM:616450|HGNC:HGNC:28670|Ensembl:ENSG00000142634|Vega:OTTHUMG00000002254 +79183 TTPAL HGNC:HGNC:16114|Ensembl:ENSG00000124120|Vega:OTTHUMG00000032536 +79184 BRCC3 MIM:300617|HGNC:HGNC:24185|Ensembl:ENSG00000185515|Vega:OTTHUMG00000022658 +79187 FSD1 MIM:609828|HGNC:HGNC:13745|Ensembl:ENSG00000105255|Vega:OTTHUMG00000181881 +79188 TMEM43 MIM:612048|HGNC:HGNC:28472|Ensembl:ENSG00000170876|Vega:OTTHUMG00000129802 +79190 IRX6 MIM:606196|HGNC:HGNC:14675|Ensembl:ENSG00000159387|Vega:OTTHUMG00000172239 +79191 IRX3 MIM:612985|HGNC:HGNC:14360|Ensembl:ENSG00000177508|Vega:OTTHUMG00000133200 +79192 IRX1 MIM:606197|HGNC:HGNC:14358|Ensembl:ENSG00000170549|Vega:OTTHUMG00000161632 +79228 THOC6 MIM:615403|HGNC:HGNC:28369|Ensembl:ENSG00000131652|Vega:OTTHUMG00000177451 +79230 ZNF557 HGNC:HGNC:28632|Ensembl:ENSG00000130544|Vega:OTTHUMG00000181977 +79231 ZNF33CP HGNC:HGNC:30957 +79232 ZNF37CP HGNC:HGNC:29445 +79258 MMEL1 HGNC:HGNC:14668|Ensembl:ENSG00000142606|Vega:OTTHUMG00000000846 +79269 DCAF10 HGNC:HGNC:23686|Ensembl:ENSG00000122741|Vega:OTTHUMG00000019934 +79272 OR52X1P HGNC:HGNC:14790 +79273 OR7E94P HGNC:HGNC:14789 +79274 OR52L2P HGNC:HGNC:14788 +79282 OR7E93P HGNC:HGNC:14780 +79283 OR5P1P HGNC:HGNC:14779 +79289 OR5H8 HGNC:HGNC:14773|Vega:OTTHUMG00000154298 +79290 OR13A1 HGNC:HGNC:14772|Ensembl:ENSG00000256574|Vega:OTTHUMG00000018080 +79291 OR5H7P HGNC:HGNC:14771 +79294 OR4C7P HGNC:HGNC:14768 +79295 OR5H6 HGNC:HGNC:14767|Ensembl:ENSG00000230301|Vega:OTTHUMG00000160078 +79296 OR52E1 HGNC:HGNC:14766|Vega:OTTHUMG00000066611 +79297 OR5H5P HGNC:HGNC:14765 +79299 OR5H4P HGNC:HGNC:14763 +79300 OR51P1P HGNC:HGNC:14762 +79301 OR9L1P HGNC:HGNC:14761 +79302 OR52J1P HGNC:HGNC:14760 +79306 OR4K7P HGNC:HGNC:14756 +79308 OR4P1P HGNC:HGNC:14754 +79309 OR5H3P HGNC:HGNC:14753 +79310 OR5H2 HGNC:HGNC:14752|Ensembl:ENSG00000197938|Vega:OTTHUMG00000160080 +79312 OR1AA1P HGNC:HGNC:14750 +79313 OR2AD1P HGNC:HGNC:14749 +79314 OR4K6P HGNC:HGNC:14748 +79315 OR7E91P HGNC:HGNC:14747 +79316 OR8B9P HGNC:HGNC:14746 +79317 OR4K5 HGNC:HGNC:14745|Ensembl:ENSG00000176281|Vega:OTTHUMG00000170627 +79318 OR4K4P HGNC:HGNC:14744 +79321 OR6M3P HGNC:HGNC:14741 +79322 OR4N1P HGNC:HGNC:14740 +79323 OR6E1P HGNC:HGNC:14739 +79324 OR51G1 HGNC:HGNC:14738|Ensembl:ENSG00000278870|Vega:OTTHUMG00000066532 +79331 OR2AF1P HGNC:HGNC:14719 +79334 OR11H2 HGNC:HGNC:14716|Ensembl:ENSG00000258453|Vega:OTTHUMG00000170597 +79336 OR5AH1P HGNC:HGNC:14714 +79339 OR51B4 HGNC:HGNC:14708|Ensembl:ENSG00000183251|Vega:OTTHUMG00000066665 +79342 OR51B3P HGNC:HGNC:14706 +79345 OR51B2 HGNC:HGNC:14703|Ensembl:ENSG00000279012|Vega:OTTHUMG00000066682 +79346 OR4C5 HGNC:HGNC:14702 +79363 RSG1 HGNC:HGNC:28127|Ensembl:ENSG00000132881|Vega:OTTHUMG00000002214 +79364 ZXDC MIM:615746|HGNC:HGNC:28160|Ensembl:ENSG00000070476|Vega:OTTHUMG00000162754 +79365 BHLHE41 MIM:606200|HGNC:HGNC:16617|Ensembl:ENSG00000123095|Vega:OTTHUMG00000169174 +79366 HMGN5 MIM:300385|HGNC:HGNC:8013|Ensembl:ENSG00000198157|Vega:OTTHUMG00000021911 +79368 FCRL2 MIM:606509|HGNC:HGNC:14875|Ensembl:ENSG00000132704|Vega:OTTHUMG00000019399 +79369 B3GNT4 MIM:605864|HGNC:HGNC:15683|Ensembl:ENSG00000176383|Vega:OTTHUMG00000168917 +79370 BCL2L14 MIM:606126|HGNC:HGNC:16657|Ensembl:ENSG00000121380|Vega:OTTHUMG00000159528 +79400 NOX5 MIM:606572|HGNC:HGNC:14874|Ensembl:ENSG00000255346|Vega:OTTHUMG00000133320 +79411 GLB1L HGNC:HGNC:28129|Ensembl:ENSG00000163521|Vega:OTTHUMG00000133133 +79412 KREMEN2 MIM:609899|HGNC:HGNC:18797|Ensembl:ENSG00000131650|Vega:OTTHUMG00000128976 +79413 ZBED2 MIM:615246|HGNC:HGNC:20710|Ensembl:ENSG00000177494|Vega:OTTHUMG00000074061 +79414 LRFN3 MIM:612809|HGNC:HGNC:28370|Ensembl:ENSG00000126243|Vega:OTTHUMG00000181740 +79415 C17orf62 HGNC:HGNC:28672|Ensembl:ENSG00000178927|Vega:OTTHUMG00000178770 +79424 CYP3AP2 - +79441 HAUS3 MIM:613430|HGNC:HGNC:28719|Ensembl:ENSG00000214367|Vega:OTTHUMG00000159805 +79442 LRRC2 MIM:607180|HGNC:HGNC:14676|Ensembl:ENSG00000163827|Vega:OTTHUMG00000133479 +79443 FYCO1 MIM:607182|HGNC:HGNC:14673|Ensembl:ENSG00000163820|Vega:OTTHUMG00000133447 +79444 BIRC7 MIM:605737|HGNC:HGNC:13702|Ensembl:ENSG00000101197|Vega:OTTHUMG00000032957 +79446 WDR25 HGNC:HGNC:21064|Ensembl:ENSG00000176473|Vega:OTTHUMG00000171585 +79447 PAGR1 MIM:612033|HGNC:HGNC:28707|Ensembl:ENSG00000280789|Vega:OTTHUMG00000177143 +79465 ULBP3 MIM:605699|HGNC:HGNC:14895|Ensembl:ENSG00000131019|Vega:OTTHUMG00000015811 +79469 DLEU2L HGNC:HGNC:13225 +79470 OR51J1 HGNC:HGNC:14856|Vega:OTTHUMG00000066666 +79473 OR52N1 HGNC:HGNC:14853|Ensembl:ENSG00000181001|Vega:OTTHUMG00000168800 +79476 OR5AL2P HGNC:HGNC:14850 +79482 OR5AL1 HGNC:HGNC:14844|Vega:OTTHUMG00000154218 +79483 OR5BD1P HGNC:HGNC:14843 +79488 OR10D5P HGNC:HGNC:14838 +79490 OR10G6 HGNC:HGNC:14836 +79491 OR5BM1P HGNC:HGNC:14835 +79492 OR7E97P HGNC:HGNC:14834 +79494 OR8K2P HGNC:HGNC:14832 +79498 OR8I1P HGNC:HGNC:14828 +79499 OR7L1P HGNC:HGNC:14827 +79501 OR4F5 HGNC:HGNC:14825|Ensembl:ENSG00000186092|Vega:OTTHUMG00000001094 +79504 OR4G4P HGNC:HGNC:14822 +79508 OR5M7P HGNC:HGNC:14818 +79512 OR5M6P HGNC:HGNC:14814 +79513 OR10R1P HGNC:HGNC:14813 +79514 OR10T1P HGNC:HGNC:14812 +79515 OR10G5P HGNC:HGNC:14811 +79518 OR5M4P HGNC:HGNC:14808 +79521 OR52S1P HGNC:HGNC:14805 +79523 OR5M2P HGNC:HGNC:14803 +79525 OR51A5P HGNC:HGNC:14801 +79526 OR4C10P HGNC:HGNC:14800 +79528 OR4R1P HGNC:HGNC:14798 +79529 OR52J2P HGNC:HGNC:14797 +79530 OR4C9P HGNC:HGNC:14796 +79532 OR51A3P HGNC:HGNC:14794 +79533 OR52E3P HGNC:HGNC:14793 +79534 OR4V1P HGNC:HGNC:14736 +79537 OR7E90P HGNC:HGNC:14733 +79538 OR13I1P HGNC:HGNC:14732 +79540 OR7E89P HGNC:HGNC:14730 +79541 OR2A4 HGNC:HGNC:14729|Ensembl:ENSG00000180658|Vega:OTTHUMG00000016316 +79544 OR4K1 HGNC:HGNC:14726|Ensembl:ENSG00000155249|Vega:OTTHUMG00000170633 +79546 OR6M2P HGNC:HGNC:14713 +79547 OR2AL1P HGNC:HGNC:14712 +79549 OR6J1 HGNC:HGNC:14707|Vega:OTTHUMG00000168897 +79550 OR4C4P HGNC:HGNC:14700 +79567 RIPOR1 HGNC:HGNC:25836|Ensembl:ENSG00000039523|Vega:OTTHUMG00000137536 +79568 MAIP1 MIM:617267|HGNC:HGNC:26198|Ensembl:ENSG00000162972|Vega:OTTHUMG00000132771 +79570 NKAIN1 MIM:612871|HGNC:HGNC:25743|Ensembl:ENSG00000084628|Vega:OTTHUMG00000003788 +79571 GCC1 MIM:607418|HGNC:HGNC:19095|Ensembl:ENSG00000179562|Vega:OTTHUMG00000023590 +79572 ATP13A3 MIM:610232|HGNC:HGNC:24113|Ensembl:ENSG00000133657|Vega:OTTHUMG00000156034 +79573 TTC13 HGNC:HGNC:26204|Ensembl:ENSG00000143643|Vega:OTTHUMG00000037788 +79574 EPS8L3 MIM:614989|HGNC:HGNC:21297|Ensembl:ENSG00000198758|Vega:OTTHUMG00000011651 +79575 ABHD8 HGNC:HGNC:23759|Ensembl:ENSG00000127220|Vega:OTTHUMG00000182663 +79576 NKAP MIM:300766|HGNC:HGNC:29873|Ensembl:ENSG00000101882|Vega:OTTHUMG00000022284 +79577 CDC73 MIM:607393|HGNC:HGNC:16783|Ensembl:ENSG00000134371|Vega:OTTHUMG00000035676 +79581 SLC52A2 MIM:607882|HGNC:HGNC:30224|Ensembl:ENSG00000185803|Vega:OTTHUMG00000165168 +79582 SPAG16 MIM:612173|HGNC:HGNC:23225|Ensembl:ENSG00000144451|Vega:OTTHUMG00000133015 +79583 TMEM231 MIM:614949|HGNC:HGNC:37234|Ensembl:ENSG00000205084|Vega:OTTHUMG00000177132 +79585 CORO7 MIM:611668|HGNC:HGNC:26161|Ensembl:ENSG00000262246|Vega:OTTHUMG00000129465 +79586 CHPF MIM:610405|HGNC:HGNC:24291|Ensembl:ENSG00000123989|Vega:OTTHUMG00000058929 +79587 CARS2 MIM:612800|HGNC:HGNC:25695|Ensembl:ENSG00000134905|Vega:OTTHUMG00000017347 +79589 RNF128 MIM:300439|HGNC:HGNC:21153|Ensembl:ENSG00000133135|Vega:OTTHUMG00000022151 +79590 MRPL24 MIM:611836|HGNC:HGNC:14037|Ensembl:ENSG00000143314|Vega:OTTHUMG00000041296 +79591 C10orf76 HGNC:HGNC:25788|Ensembl:ENSG00000120029|Vega:OTTHUMG00000018943 +79594 MUL1 MIM:612037|HGNC:HGNC:25762|Ensembl:ENSG00000090432|Vega:OTTHUMG00000002838 +79595 SAP130 MIM:609697|HGNC:HGNC:29813|Ensembl:ENSG00000136715|Vega:OTTHUMG00000131571 +79596 RNF219 MIM:615906|HGNC:HGNC:20308|Ensembl:ENSG00000152193|Vega:OTTHUMG00000017122 +79598 CEP97 MIM:615864|HGNC:HGNC:26244|Ensembl:ENSG00000182504|Vega:OTTHUMG00000159162 +79600 TCTN1 MIM:609863|HGNC:HGNC:26113|Ensembl:ENSG00000204852|Vega:OTTHUMG00000150051 +79602 ADIPOR2 MIM:607946|HGNC:HGNC:24041|Ensembl:ENSG00000006831|Vega:OTTHUMG00000130139 +79603 CERS4 MIM:615334|HGNC:HGNC:23747|Ensembl:ENSG00000090661|Vega:OTTHUMG00000172570 +79605 PGBD5 MIM:616791|HGNC:HGNC:19405|Ensembl:ENSG00000177614|Vega:OTTHUMG00000037759 +79607 FAM118B MIM:616587|HGNC:HGNC:26110|Ensembl:ENSG00000197798|Vega:OTTHUMG00000165817 +79608 RIC3 MIM:610509|HGNC:HGNC:30338|Ensembl:ENSG00000166405|Vega:OTTHUMG00000165694 +79609 VCPKMT MIM:615260|HGNC:HGNC:20352|Ensembl:ENSG00000100483|Vega:OTTHUMG00000029531 +79611 ACSS3 MIM:614356|HGNC:HGNC:24723|Ensembl:ENSG00000111058|Vega:OTTHUMG00000170179 +79612 NAA16 HGNC:HGNC:26164|Ensembl:ENSG00000172766|Vega:OTTHUMG00000016791 +79613 TANGO6 HGNC:HGNC:25749|Ensembl:ENSG00000103047|Vega:OTTHUMG00000176743 +79616 CCNJL HGNC:HGNC:25876|Ensembl:ENSG00000135083|Vega:OTTHUMG00000130325 +79618 HMBOX1 HGNC:HGNC:26137|Ensembl:ENSG00000147421|Vega:OTTHUMG00000172138 +79621 RNASEH2B MIM:610326|HGNC:HGNC:25671|Ensembl:ENSG00000136104|Vega:OTTHUMG00000016937 +79622 SNRNP25 HGNC:HGNC:14161|Ensembl:ENSG00000161981|Vega:OTTHUMG00000060720 +79623 GALNT14 MIM:608225|HGNC:HGNC:22946|Ensembl:ENSG00000158089|Vega:OTTHUMG00000074077 +79624 ARMT1 MIM:616332|HGNC:HGNC:17872|Ensembl:ENSG00000146476|Vega:OTTHUMG00000015838 +79625 NDNF MIM:616506|HGNC:HGNC:26256|Ensembl:ENSG00000173376|Vega:OTTHUMG00000132973 +79626 TNFAIP8L2 MIM:612112|HGNC:HGNC:26277|Ensembl:ENSG00000163154|Vega:OTTHUMG00000012259 +79627 OGFRL1 HGNC:HGNC:21378|Ensembl:ENSG00000119900|Vega:OTTHUMG00000015000 +79628 SH3TC2 MIM:608206|HGNC:HGNC:29427|Ensembl:ENSG00000169247|Vega:OTTHUMG00000129930 +79629 OCEL1 HGNC:HGNC:26221|Ensembl:ENSG00000099330|Vega:OTTHUMG00000182726 +79630 C1orf54 HGNC:HGNC:26258|Ensembl:ENSG00000118292|Vega:OTTHUMG00000012546 +79631 EFL1 MIM:617538|HGNC:HGNC:25789|Ensembl:ENSG00000140598|Vega:OTTHUMG00000172573 +79632 FAM184A HGNC:HGNC:20991|Ensembl:ENSG00000111879|Vega:OTTHUMG00000015471 +79633 FAT4 MIM:612411|HGNC:HGNC:23109|Ensembl:ENSG00000196159|Vega:OTTHUMG00000133100 +79634 SCRN3 MIM:614967|HGNC:HGNC:30382|Ensembl:ENSG00000144306|Vega:OTTHUMG00000132332 +79635 CCDC121 HGNC:HGNC:25833|Ensembl:ENSG00000176714|Vega:OTTHUMG00000128427 +79637 ARMC7 HGNC:HGNC:26168|Ensembl:ENSG00000125449|Vega:OTTHUMG00000179345 +79639 TMEM53 HGNC:HGNC:26186|Ensembl:ENSG00000126106|Vega:OTTHUMG00000007833 +79640 C22orf46 HGNC:HGNC:26294|Ensembl:ENSG00000184208|Vega:OTTHUMG00000151188 +79641 ROGDI MIM:614574|HGNC:HGNC:29478|Ensembl:ENSG00000067836|Vega:OTTHUMG00000129479 +79642 ARSJ MIM:610010|HGNC:HGNC:26286|Ensembl:ENSG00000180801|Vega:OTTHUMG00000161067 +79643 CHMP6 MIM:610901|HGNC:HGNC:25675|Ensembl:ENSG00000176108|Vega:OTTHUMG00000177645 +79644 SRD5A3 MIM:611715|HGNC:HGNC:25812|Ensembl:ENSG00000128039|Vega:OTTHUMG00000128733 +79645 EFCAB1 HGNC:HGNC:25678|Ensembl:ENSG00000034239|Vega:OTTHUMG00000164203 +79646 PANK3 MIM:606161|HGNC:HGNC:19365|Ensembl:ENSG00000120137|Vega:OTTHUMG00000130410 +79647 AKIRIN1 MIM:615164|HGNC:HGNC:25744|Ensembl:ENSG00000174574|Vega:OTTHUMG00000007496 +79648 MCPH1 MIM:607117|HGNC:HGNC:6954|Ensembl:ENSG00000147316|Vega:OTTHUMG00000163618 +79649 MAP7D3 MIM:300930|HGNC:HGNC:25742|Ensembl:ENSG00000129680|Vega:OTTHUMG00000022507 +79650 USB1 MIM:613276|HGNC:HGNC:25792|Ensembl:ENSG00000103005|Vega:OTTHUMG00000133456 +79651 RHBDF2 MIM:614404|HGNC:HGNC:20788|Ensembl:ENSG00000129667|Vega:OTTHUMG00000180180 +79652 TMEM204 MIM:611002|HGNC:HGNC:14158|Ensembl:ENSG00000131634|Vega:OTTHUMG00000176585 +79654 HECTD3 HGNC:HGNC:26117|Ensembl:ENSG00000126107|Vega:OTTHUMG00000008587 +79656 BEND5 HGNC:HGNC:25668|Ensembl:ENSG00000162373|Vega:OTTHUMG00000008153 +79657 RPAP3 MIM:611477|HGNC:HGNC:26151|Ensembl:ENSG00000005175|Vega:OTTHUMG00000169668 +79658 ARHGAP10 MIM:609746|HGNC:HGNC:26099|Ensembl:ENSG00000071205|Vega:OTTHUMG00000161460 +79659 DYNC2H1 MIM:603297|HGNC:HGNC:2962|Ensembl:ENSG00000187240|Vega:OTTHUMG00000165941 +79660 PPP1R3B MIM:610541|HGNC:HGNC:14942|Ensembl:ENSG00000173281|Vega:OTTHUMG00000129329 +79661 NEIL1 MIM:608844|HGNC:HGNC:18448|Ensembl:ENSG00000140398|Vega:OTTHUMG00000142821 +79663 HSPBAP1 MIM:608263|HGNC:HGNC:16389|Ensembl:ENSG00000169087|Vega:OTTHUMG00000159550 +79664 ICE2 MIM:610835|HGNC:HGNC:29885|Ensembl:ENSG00000128915|Vega:OTTHUMG00000132764 +79665 DHX40 MIM:607570|HGNC:HGNC:18018|Ensembl:ENSG00000108406|Vega:OTTHUMG00000179401 +79666 PLEKHF2 MIM:615208|HGNC:HGNC:20757|Ensembl:ENSG00000175895|Vega:OTTHUMG00000164660 +79667 KLF3-AS1 HGNC:HGNC:25796|Ensembl:ENSG00000231160 +79668 PARP8 HGNC:HGNC:26124|Ensembl:ENSG00000151883|Vega:OTTHUMG00000096969 +79669 C3orf52 MIM:611956|HGNC:HGNC:26255|Ensembl:ENSG00000114529|Vega:OTTHUMG00000159230 +79670 ZCCHC6 MIM:613467|HGNC:HGNC:25817|Ensembl:ENSG00000083223|Vega:OTTHUMG00000020137 +79671 NLRX1 MIM:611947|HGNC:HGNC:29890|Ensembl:ENSG00000160703|Vega:OTTHUMG00000154476 +79672 FN3KRP MIM:611683|HGNC:HGNC:25700|Ensembl:ENSG00000141560|Vega:OTTHUMG00000177846 +79673 ZNF329 HGNC:HGNC:14209|Ensembl:ENSG00000181894|Vega:OTTHUMG00000183453 +79674 VEPH1 MIM:609594|HGNC:HGNC:25735|Ensembl:ENSG00000197415|Vega:OTTHUMG00000158711 +79675 FASTKD1 MIM:617529|HGNC:HGNC:26150|Ensembl:ENSG00000138399|Vega:OTTHUMG00000154953 +79676 OGFOD2 HGNC:HGNC:25823|Ensembl:ENSG00000111325|Vega:OTTHUMG00000168778 +79677 SMC6 MIM:609387|HGNC:HGNC:20466|Ensembl:ENSG00000163029|Vega:OTTHUMG00000090675 +79679 VTCN1 MIM:608162|HGNC:HGNC:28873|Ensembl:ENSG00000134258|Vega:OTTHUMG00000012118 +79680 RTL10 HGNC:HGNC:26112|Ensembl:ENSG00000215012|Vega:OTTHUMG00000030314 +79682 CENPU MIM:611511|HGNC:HGNC:21348|Ensembl:ENSG00000151725|Vega:OTTHUMG00000160499 +79683 ZDHHC14 HGNC:HGNC:20341|Ensembl:ENSG00000175048|Vega:OTTHUMG00000015896 +79684 MSANTD2 HGNC:HGNC:26266|Ensembl:ENSG00000120458|Vega:OTTHUMG00000165931 +79685 SAP30L MIM:610398|HGNC:HGNC:25663|Ensembl:ENSG00000164576|Vega:OTTHUMG00000130146 +79689 STEAP4 MIM:611098|HGNC:HGNC:21923|Ensembl:ENSG00000127954|Vega:OTTHUMG00000153853 +79690 GAL3ST4 MIM:608235|HGNC:HGNC:24145|Ensembl:ENSG00000197093|Vega:OTTHUMG00000154885 +79691 QTRT2 HGNC:HGNC:25771|Ensembl:ENSG00000151576|Vega:OTTHUMG00000159336 +79692 ZNF322 MIM:610847|HGNC:HGNC:23640|Ensembl:ENSG00000181315|Vega:OTTHUMG00000014460 +79693 YRDC MIM:612276|HGNC:HGNC:28905|Ensembl:ENSG00000196449|Vega:OTTHUMG00000004318 +79694 MANEA MIM:612327|HGNC:HGNC:21072|Ensembl:ENSG00000172469|Vega:OTTHUMG00000016296 +79695 GALNT12 MIM:610290|HGNC:HGNC:19877|Ensembl:ENSG00000119514|Vega:OTTHUMG00000020348 +79696 ZC2HC1C HGNC:HGNC:20354|Ensembl:ENSG00000119703|Vega:OTTHUMG00000167439 +79697 RIOX1 MIM:611919|HGNC:HGNC:20968|Ensembl:ENSG00000170468|Vega:OTTHUMG00000166530 +79698 ZMAT4 HGNC:HGNC:25844|Ensembl:ENSG00000165061|Vega:OTTHUMG00000164049 +79699 ZYG11B HGNC:HGNC:25820|Ensembl:ENSG00000162378|Vega:OTTHUMG00000008938 +79701 OGFOD3 HGNC:HGNC:26174|Ensembl:ENSG00000181396|Vega:OTTHUMG00000178679 +79703 C11orf80 MIM:616109|HGNC:HGNC:26197|Ensembl:ENSG00000173715|Vega:OTTHUMG00000167164 +79705 LRRK1 MIM:610986|HGNC:HGNC:18608|Ensembl:ENSG00000154237|Vega:OTTHUMG00000165514 +79706 PRKRIP1 MIM:617458|HGNC:HGNC:21894|Ensembl:ENSG00000128563|Vega:OTTHUMG00000157717 +79707 NOL9 HGNC:HGNC:26265|Ensembl:ENSG00000162408|Vega:OTTHUMG00000000904 +79709 COLGALT1 MIM:617531|HGNC:HGNC:26182|Ensembl:ENSG00000130309|Vega:OTTHUMG00000182893 +79710 MORC4 MIM:300970|HGNC:HGNC:23485|Ensembl:ENSG00000133131|Vega:OTTHUMG00000022155 +79711 IPO4 HGNC:HGNC:19426|Ensembl:ENSG00000196497|Vega:OTTHUMG00000028801 +79712 GTDC1 MIM:610165|HGNC:HGNC:20887|Ensembl:ENSG00000121964|Vega:OTTHUMG00000131835 +79713 IGFLR1 MIM:614143|HGNC:HGNC:23620|Ensembl:ENSG00000126246|Vega:OTTHUMG00000182064 +79714 CCDC51 HGNC:HGNC:25714|Ensembl:ENSG00000164051|Vega:OTTHUMG00000133534 +79716 NPEPL1 HGNC:HGNC:16244|Ensembl:ENSG00000215440|Vega:OTTHUMG00000033060 +79717 PPCS MIM:609853|HGNC:HGNC:25686|Ensembl:ENSG00000127125|Vega:OTTHUMG00000007332 +79718 TBL1XR1 MIM:608628|HGNC:HGNC:29529|Ensembl:ENSG00000177565|Vega:OTTHUMG00000157140 +79719 AAGAB MIM:614888|HGNC:HGNC:25662|Ensembl:ENSG00000103591|Vega:OTTHUMG00000172246 +79720 VPS37B MIM:610037|HGNC:HGNC:25754|Ensembl:ENSG00000139722|Vega:OTTHUMG00000168767 +79722 ANKRD55 MIM:615189|HGNC:HGNC:25681|Ensembl:ENSG00000164512|Vega:OTTHUMG00000162305 +79723 SUV39H2 MIM:606503|HGNC:HGNC:17287|Ensembl:ENSG00000152455|Vega:OTTHUMG00000017718 +79724 ZNF768 HGNC:HGNC:26273|Ensembl:ENSG00000169957|Vega:OTTHUMG00000132392 +79725 THAP9 MIM:612537|HGNC:HGNC:23192|Ensembl:ENSG00000168152|Vega:OTTHUMG00000130291 +79726 WDR59 MIM:617418|HGNC:HGNC:25706|Ensembl:ENSG00000103091|Vega:OTTHUMG00000170831 +79727 LIN28A MIM:611043|HGNC:HGNC:15986|Ensembl:ENSG00000131914|Vega:OTTHUMG00000003550 +79728 PALB2 MIM:610355|HGNC:HGNC:26144|Ensembl:ENSG00000083093|Vega:OTTHUMG00000177097 +79729 SH3D21 HGNC:HGNC:26236|Ensembl:ENSG00000214193|Vega:OTTHUMG00000007868 +79730 NSUN7 MIM:617185|HGNC:HGNC:25857|Ensembl:ENSG00000179299|Vega:OTTHUMG00000128597 +79731 NARS2 MIM:612803|HGNC:HGNC:26274|Ensembl:ENSG00000137513|Vega:OTTHUMG00000166702 +79733 E2F8 MIM:612047|HGNC:HGNC:24727|Ensembl:ENSG00000129173|Vega:OTTHUMG00000166102 +79734 KCTD17 MIM:616386|HGNC:HGNC:25705|Ensembl:ENSG00000100379|Vega:OTTHUMG00000150532 +79735 TBC1D17 MIM:616659|HGNC:HGNC:25699|Ensembl:ENSG00000104946|Vega:OTTHUMG00000183376 +79736 TEFM MIM:616422|HGNC:HGNC:26223|Ensembl:ENSG00000172171|Vega:OTTHUMG00000179029 +79738 BBS10 MIM:610148|HGNC:HGNC:26291|Ensembl:ENSG00000179941|Vega:OTTHUMG00000147352 +79739 TTLL7 HGNC:HGNC:26242|Ensembl:ENSG00000137941|Vega:OTTHUMG00000009932 +79740 ZBBX HGNC:HGNC:26245|Ensembl:ENSG00000169064|Vega:OTTHUMG00000133560 +79741 CCDC7 HGNC:HGNC:26533|Ensembl:ENSG00000216937 +79742 CXorf36 MIM:300959|HGNC:HGNC:25866|Ensembl:ENSG00000147113|Vega:OTTHUMG00000021403 +79744 ZNF419 MIM:617410|HGNC:HGNC:20648|Ensembl:ENSG00000105136|Vega:OTTHUMG00000037073 +79745 CLIP4 HGNC:HGNC:26108|Ensembl:ENSG00000115295|Vega:OTTHUMG00000097837 +79746 ECHDC3 HGNC:HGNC:23489|Ensembl:ENSG00000134463|Vega:OTTHUMG00000017675 +79747 ADGB MIM:614630|HGNC:HGNC:21212|Ensembl:ENSG00000118492|Vega:OTTHUMG00000015758 +79748 LMAN1L MIM:609548|HGNC:HGNC:6632|Ensembl:ENSG00000140506|Vega:OTTHUMG00000142813 +79750 ZNF385D HGNC:HGNC:26191|Ensembl:ENSG00000151789|Vega:OTTHUMG00000130484 +79751 SLC25A22 MIM:609302|HGNC:HGNC:19954|Ensembl:ENSG00000177542|Vega:OTTHUMG00000133310 +79752 ZFAND1 HGNC:HGNC:25858|Ensembl:ENSG00000104231|Vega:OTTHUMG00000164684 +79753 SNIP1 MIM:608241|HGNC:HGNC:30587|Ensembl:ENSG00000163877|Vega:OTTHUMG00000004225 +79754 ASB13 MIM:615055|HGNC:HGNC:19765|Ensembl:ENSG00000196372|Vega:OTTHUMG00000017603 +79755 ZNF750 MIM:610226|HGNC:HGNC:25843|Ensembl:ENSG00000141579|Vega:OTTHUMG00000177822 +79758 DHRS12 MIM:616163|HGNC:HGNC:25832|Ensembl:ENSG00000102796|Vega:OTTHUMG00000016952 +79759 ZNF668 MIM:617103|HGNC:HGNC:25821|Ensembl:ENSG00000167394|Vega:OTTHUMG00000047357 +79760 GEMIN7 MIM:607419|HGNC:HGNC:20045|Ensembl:ENSG00000142252|Vega:OTTHUMG00000181768 +79762 C1orf115 HGNC:HGNC:25873|Ensembl:ENSG00000162817|Vega:OTTHUMG00000037361 +79763 ISOC2 MIM:612928|HGNC:HGNC:26278|Ensembl:ENSG00000063241|Vega:OTTHUMG00000180830 +79767 ELMO3 MIM:606422|HGNC:HGNC:17289|Ensembl:ENSG00000102890|Vega:OTTHUMG00000133570 +79768 KATNBL1 MIM:616235|HGNC:HGNC:26199|Ensembl:ENSG00000134152|Vega:OTTHUMG00000129368 +79770 TXNDC15 HGNC:HGNC:20652|Ensembl:ENSG00000113621|Vega:OTTHUMG00000129115 +79772 MCTP1 MIM:616296|HGNC:HGNC:26183|Ensembl:ENSG00000175471|Vega:OTTHUMG00000162742 +79774 GRTP1 HGNC:HGNC:20310|Ensembl:ENSG00000139835|Vega:OTTHUMG00000017381 +79776 ZFHX4 MIM:606940|HGNC:HGNC:30939|Ensembl:ENSG00000091656|Vega:OTTHUMG00000164557 +79777 ACBD4 HGNC:HGNC:23337|Ensembl:ENSG00000181513|Vega:OTTHUMG00000180111 +79778 MICALL2 HGNC:HGNC:29672|Ensembl:ENSG00000164877|Vega:OTTHUMG00000119021 +79780 CCDC82 HGNC:HGNC:26282|Ensembl:ENSG00000149231|Vega:OTTHUMG00000167678 +79781 IQCA1 HGNC:HGNC:26195|Ensembl:ENSG00000132321|Vega:OTTHUMG00000153058 +79782 LRRC31 HGNC:HGNC:26261|Ensembl:ENSG00000114248|Vega:OTTHUMG00000164421 +79783 SUGCT MIM:609187|HGNC:HGNC:16001|Ensembl:ENSG00000175600|Vega:OTTHUMG00000155094 +79784 MYH14 MIM:608568|HGNC:HGNC:23212|Ensembl:ENSG00000105357|Vega:OTTHUMG00000183034 +79785 RERGL HGNC:HGNC:26213|Ensembl:ENSG00000111404|Vega:OTTHUMG00000168820 +79786 KLHL36 HGNC:HGNC:17844|Ensembl:ENSG00000135686|Vega:OTTHUMG00000137642 +79788 ZNF665 HGNC:HGNC:25885|Ensembl:ENSG00000197497|Vega:OTTHUMG00000182885 +79789 CLMN MIM:611121|HGNC:HGNC:19972|Ensembl:ENSG00000165959|Vega:OTTHUMG00000171629 +79791 FBXO31 MIM:609102|HGNC:HGNC:16510|Ensembl:ENSG00000103264|Vega:OTTHUMG00000175685 +79792 GSDMD MIM:617042|HGNC:HGNC:25697|Ensembl:ENSG00000104518|Vega:OTTHUMG00000165132 +79794 C12orf49 HGNC:HGNC:26128|Ensembl:ENSG00000111412|Vega:OTTHUMG00000169392 +79796 ALG9 MIM:606941|HGNC:HGNC:15672|Ensembl:ENSG00000086848|Vega:OTTHUMG00000166819 +79797 ZNF408 MIM:616454|HGNC:HGNC:20041|Ensembl:ENSG00000175213|Vega:OTTHUMG00000166568 +79798 ARMC5 MIM:615549|HGNC:HGNC:25781|Ensembl:ENSG00000140691|Vega:OTTHUMG00000176618 +79799 UGT2A3 MIM:616382|HGNC:HGNC:28528|Ensembl:ENSG00000135220|Vega:OTTHUMG00000129408 +79800 CARF MIM:607586|HGNC:HGNC:14435|Ensembl:ENSG00000138380|Vega:OTTHUMG00000154528 +79801 SHCBP1 MIM:611027|HGNC:HGNC:29547|Ensembl:ENSG00000171241|Vega:OTTHUMG00000132540 +79802 HHIPL2 HGNC:HGNC:25842|Ensembl:ENSG00000143512|Vega:OTTHUMG00000037545 +79803 HPS6 MIM:607522|HGNC:HGNC:18817|Ensembl:ENSG00000166189|Vega:OTTHUMG00000018945 +79804 HAND2-AS1 MIM:617240|HGNC:HGNC:48872|Ensembl:ENSG00000237125 +79805 VASH2 MIM:610471|HGNC:HGNC:25723|Ensembl:ENSG00000143494|Vega:OTTHUMG00000036925 +79807 GSTCD MIM:615912|HGNC:HGNC:25806|Ensembl:ENSG00000138780|Vega:OTTHUMG00000131211 +79809 TTC21B MIM:612014|HGNC:HGNC:25660|Ensembl:ENSG00000123607|Vega:OTTHUMG00000154083 +79810 PTCD2 MIM:615484|HGNC:HGNC:25734|Ensembl:ENSG00000049883|Vega:OTTHUMG00000100953 +79811 SLTM HGNC:HGNC:20709|Ensembl:ENSG00000137776|Vega:OTTHUMG00000074033 +79812 MMRN2 MIM:608925|HGNC:HGNC:19888|Ensembl:ENSG00000173269|Vega:OTTHUMG00000018663 +79813 EHMT1 MIM:607001|HGNC:HGNC:24650|Ensembl:ENSG00000181090|Vega:OTTHUMG00000020995 +79814 AGMAT HGNC:HGNC:18407|Ensembl:ENSG00000116771|Vega:OTTHUMG00000002357 +79815 NIPAL2 HGNC:HGNC:25854|Ensembl:ENSG00000104361|Vega:OTTHUMG00000164668 +79816 TLE6 MIM:612399|HGNC:HGNC:30788|Ensembl:ENSG00000104953|Vega:OTTHUMG00000156793 +79817 MOB3B HGNC:HGNC:23825|Ensembl:ENSG00000120162|Vega:OTTHUMG00000019717 +79818 ZNF552 HGNC:HGNC:26135|Ensembl:ENSG00000178935|Vega:OTTHUMG00000183478 +79819 WDR78 HGNC:HGNC:26252|Ensembl:ENSG00000152763|Vega:OTTHUMG00000009165 +79820 CATSPERB MIM:611169|HGNC:HGNC:20500|Ensembl:ENSG00000133962|Vega:OTTHUMG00000171118 +79822 ARHGAP28 MIM:610592|HGNC:HGNC:25509|Ensembl:ENSG00000088756|Vega:OTTHUMG00000167698 +79823 CAMKMT MIM:609559|HGNC:HGNC:26276|Ensembl:ENSG00000143919|Vega:OTTHUMG00000128761 +79825 EFCC1 HGNC:HGNC:25692|Ensembl:ENSG00000114654|Vega:OTTHUMG00000158996 +79827 CLMP MIM:611693|HGNC:HGNC:24039|Ensembl:ENSG00000166250|Vega:OTTHUMG00000166031 +79828 METTL8 MIM:609525|HGNC:HGNC:25856|Ensembl:ENSG00000123600|Vega:OTTHUMG00000132261 +79829 NAA40 HGNC:HGNC:25845|Ensembl:ENSG00000110583|Vega:OTTHUMG00000167784 +79830 ZMYM1 HGNC:HGNC:26253|Ensembl:ENSG00000197056|Vega:OTTHUMG00000004374 +79831 KDM8 MIM:611917|HGNC:HGNC:25840|Ensembl:ENSG00000155666|Vega:OTTHUMG00000131677 +79832 QSER1 HGNC:HGNC:26154|Ensembl:ENSG00000060749|Vega:OTTHUMG00000166220 +79833 GEMIN6 MIM:607006|HGNC:HGNC:20044|Ensembl:ENSG00000152147|Vega:OTTHUMG00000128588 +79834 PEAK1 MIM:614248|HGNC:HGNC:29431|Ensembl:ENSG00000173517|Vega:OTTHUMG00000172618 +79836 LONRF3 HGNC:HGNC:21152|Ensembl:ENSG00000175556|Vega:OTTHUMG00000022262 +79837 PIP4K2C MIM:617104|HGNC:HGNC:23786|Ensembl:ENSG00000166908|Vega:OTTHUMG00000170144 +79838 TMC5 MIM:617197|HGNC:HGNC:22999|Ensembl:ENSG00000103534|Vega:OTTHUMG00000131458 +79839 CCDC102B HGNC:HGNC:26295|Ensembl:ENSG00000150636|Vega:OTTHUMG00000132808 +79840 NHEJ1 MIM:611290|HGNC:HGNC:25737|Ensembl:ENSG00000187736|Vega:OTTHUMG00000133127 +79841 AGBL2 MIM:617345|HGNC:HGNC:26296|Ensembl:ENSG00000165923|Vega:OTTHUMG00000165368 +79842 ZBTB3 HGNC:HGNC:22918|Ensembl:ENSG00000185670|Vega:OTTHUMG00000167608 +79843 FAM124B HGNC:HGNC:26224|Ensembl:ENSG00000124019|Vega:OTTHUMG00000133168 +79844 ZDHHC11 HGNC:HGNC:19158|Ensembl:ENSG00000188818|Vega:OTTHUMG00000090319 +79845 RNF122 HGNC:HGNC:21147|Ensembl:ENSG00000133874|Vega:OTTHUMG00000163960 +79846 CFAP69 HGNC:HGNC:26107|Ensembl:ENSG00000105792|Vega:OTTHUMG00000023434 +79847 MFSD13A HGNC:HGNC:26196|Ensembl:ENSG00000138111|Vega:OTTHUMG00000018961 +79848 CSPP1 MIM:611654|HGNC:HGNC:26193|Ensembl:ENSG00000104218|Vega:OTTHUMG00000164564 +79849 PDZD3 MIM:607146|HGNC:HGNC:19891|Ensembl:ENSG00000172367|Vega:OTTHUMG00000166224 +79850 FAM57A MIM:611627|HGNC:HGNC:29646|Ensembl:ENSG00000167695|Vega:OTTHUMG00000177491 +79852 EPHX3 MIM:617400|HGNC:HGNC:23760|Ensembl:ENSG00000105131|Vega:OTTHUMG00000183251 +79853 TM4SF20 MIM:615404|HGNC:HGNC:26230|Ensembl:ENSG00000168955|Vega:OTTHUMG00000133187 +79854 LINC00115 HGNC:HGNC:26211|Ensembl:ENSG00000225880 +79856 SNX22 HGNC:HGNC:16315|Ensembl:ENSG00000157734|Vega:OTTHUMG00000132965 +79857 FLJ13224 Ensembl:ENSG00000177340 +79858 NEK11 MIM:609779|HGNC:HGNC:18593|Ensembl:ENSG00000114670|Vega:OTTHUMG00000159654 +79861 TUBAL3 HGNC:HGNC:23534|Ensembl:ENSG00000178462|Vega:OTTHUMG00000017595 +79862 ZNF669 HGNC:HGNC:25736|Ensembl:ENSG00000188295|Vega:OTTHUMG00000040869 +79863 RBFA HGNC:HGNC:26120|Ensembl:ENSG00000101546|Vega:OTTHUMG00000132923 +79864 C11orf63 HGNC:HGNC:26288|Ensembl:ENSG00000109944|Vega:OTTHUMG00000166027 +79865 TREML2 MIM:609715|HGNC:HGNC:21092|Ensembl:ENSG00000112195|Vega:OTTHUMG00000016349 +79866 BORA MIM:610510|HGNC:HGNC:24724|Ensembl:ENSG00000136122|Vega:OTTHUMG00000017068 +79867 TCTN2 MIM:613846|HGNC:HGNC:25774|Ensembl:ENSG00000168778|Vega:OTTHUMG00000168700 +79868 ALG13 MIM:300776|HGNC:HGNC:30881|Ensembl:ENSG00000101901|Vega:OTTHUMG00000022209 +79869 CPSF7 HGNC:HGNC:30098|Ensembl:ENSG00000149532|Vega:OTTHUMG00000168198 +79870 BAALC MIM:606602|HGNC:HGNC:14333|Ensembl:ENSG00000164929|Vega:OTTHUMG00000164782 +79871 RPAP2 MIM:611476|HGNC:HGNC:25791|Ensembl:ENSG00000122484|Vega:OTTHUMG00000010288 +79872 CBLL1 MIM:606872|HGNC:HGNC:21225|Ensembl:ENSG00000105879|Vega:OTTHUMG00000154809 +79873 NUDT18 MIM:615791|HGNC:HGNC:26194|Ensembl:ENSG00000275074|Vega:OTTHUMG00000163774 +79874 RABEP2 MIM:611869|HGNC:HGNC:24817|Ensembl:ENSG00000177548|Vega:OTTHUMG00000176593 +79875 THSD4 MIM:614476|HGNC:HGNC:25835|Ensembl:ENSG00000187720|Vega:OTTHUMG00000133389 +79876 UBA5 MIM:610552|HGNC:HGNC:23230|Ensembl:ENSG00000081307|Vega:OTTHUMG00000159759 +79877 DCAKD HGNC:HGNC:26238|Ensembl:ENSG00000172992|Vega:OTTHUMG00000179947 +79879 CCDC134 HGNC:HGNC:26185|Ensembl:ENSG00000100147|Vega:OTTHUMG00000151262 +79882 ZC3H14 MIM:613279|HGNC:HGNC:20509|Ensembl:ENSG00000100722|Vega:OTTHUMG00000170803 +79883 PODNL1 HGNC:HGNC:26275|Ensembl:ENSG00000132000|Vega:OTTHUMG00000181853 +79884 MAP9 MIM:610070|HGNC:HGNC:26118|Ensembl:ENSG00000164114|Vega:OTTHUMG00000133628 +79885 HDAC11 MIM:607226|HGNC:HGNC:19086|Ensembl:ENSG00000163517|Vega:OTTHUMG00000129800 +79886 CAAP1 HGNC:HGNC:25834|Ensembl:ENSG00000120159|Vega:OTTHUMG00000019706 +79887 PLBD1 HGNC:HGNC:26215|Ensembl:ENSG00000121316|Vega:OTTHUMG00000168821 +79888 LPCAT1 MIM:610472|HGNC:HGNC:25718|Ensembl:ENSG00000153395|Vega:OTTHUMG00000131017 +79890 RIN3 MIM:610223|HGNC:HGNC:18751|Ensembl:ENSG00000100599|Vega:OTTHUMG00000171198 +79891 ZNF671 HGNC:HGNC:26279|Ensembl:ENSG00000083814|Vega:OTTHUMG00000183476 +79892 MCMBP MIM:610909|HGNC:HGNC:25782|Ensembl:ENSG00000197771|Vega:OTTHUMG00000019159 +79893 GGNBP2 MIM:612275|HGNC:HGNC:19357|Ensembl:ENSG00000278311|Vega:OTTHUMG00000188440 +79894 ZNF672 HGNC:HGNC:26179|Ensembl:ENSG00000171161|Vega:OTTHUMG00000040377 +79895 ATP8B4 MIM:609123|HGNC:HGNC:13536|Ensembl:ENSG00000104043|Vega:OTTHUMG00000172368 +79896 THNSL1 MIM:611260|HGNC:HGNC:26160|Ensembl:ENSG00000185875|Vega:OTTHUMG00000017828 +79897 RPP21 MIM:612524|HGNC:HGNC:21300|Ensembl:ENSG00000241370|Vega:OTTHUMG00000031220 +79898 ZNF613 HGNC:HGNC:25827|Ensembl:ENSG00000176024|Vega:OTTHUMG00000182424 +79899 PRR5L MIM:611728|HGNC:HGNC:25878|Ensembl:ENSG00000135362|Vega:OTTHUMG00000166334 +79901 CYBRD1 MIM:605745|HGNC:HGNC:20797|Ensembl:ENSG00000071967|Vega:OTTHUMG00000132260 +79902 NUP85 MIM:170285|HGNC:HGNC:8734|Ensembl:ENSG00000125450|Vega:OTTHUMG00000179482 +79903 NAA60 MIM:614246|HGNC:HGNC:25875|Ensembl:ENSG00000122390|Vega:OTTHUMG00000150268 +79905 TMC7 MIM:617198|HGNC:HGNC:23000|Ensembl:ENSG00000170537|Vega:OTTHUMG00000131456 +79906 MORN1 HGNC:HGNC:25852|Ensembl:ENSG00000116151|Vega:OTTHUMG00000001402 +79908 BTNL8 MIM:615606|HGNC:HGNC:26131|Ensembl:ENSG00000113303|Vega:OTTHUMG00000130932 +79912 PYROXD1 MIM:617220|HGNC:HGNC:26162|Ensembl:ENSG00000121350|Vega:OTTHUMG00000169129 +79913 ACTR5 HGNC:HGNC:14671|Ensembl:ENSG00000101442|Vega:OTTHUMG00000032456 +79915 ATAD5 MIM:609534|HGNC:HGNC:25752|Ensembl:ENSG00000176208|Vega:OTTHUMG00000132794 +79917 MAGIX HGNC:HGNC:30006|Ensembl:ENSG00000269313|Vega:OTTHUMG00000188218 +79918 SETD6 MIM:616424|HGNC:HGNC:26116|Ensembl:ENSG00000103037|Vega:OTTHUMG00000150276 +79919 C2orf54 HGNC:HGNC:26216|Ensembl:ENSG00000172478|Vega:OTTHUMG00000151906 +79921 TCEAL4 HGNC:HGNC:26121|Ensembl:ENSG00000133142|Vega:OTTHUMG00000022103 +79922 MRM1 HGNC:HGNC:26202|Ensembl:ENSG00000278619|Vega:OTTHUMG00000188443 +79923 NANOG MIM:607937|HGNC:HGNC:20857|Ensembl:ENSG00000111704|Vega:OTTHUMG00000166019 +79924 ADM2 MIM:608682|HGNC:HGNC:28898|Ensembl:ENSG00000128165|Vega:OTTHUMG00000150202 +79925 SPEF2 MIM:610172|HGNC:HGNC:26293|Ensembl:ENSG00000152582|Vega:OTTHUMG00000131111 +79927 FAM110D HGNC:HGNC:25860|Ensembl:ENSG00000197245|Vega:OTTHUMG00000007537 +79929 MAP6D1 MIM:610593|HGNC:HGNC:25753|Ensembl:ENSG00000180834|Vega:OTTHUMG00000156900 +79930 DOK3 MIM:611435|HGNC:HGNC:24583|Ensembl:ENSG00000146094|Vega:OTTHUMG00000130850 +79931 TNIP3 MIM:608019|HGNC:HGNC:19315|Ensembl:ENSG00000050730|Vega:OTTHUMG00000132969 +79932 KIAA0319L MIM:613535|HGNC:HGNC:30071|Ensembl:ENSG00000142687|Vega:OTTHUMG00000004370 +79933 SYNPO2L HGNC:HGNC:23532|Ensembl:ENSG00000166317|Vega:OTTHUMG00000018471 +79934 COQ8B MIM:615567|HGNC:HGNC:19041|Ensembl:ENSG00000123815|Vega:OTTHUMG00000182620 +79935 CNTD2 HGNC:HGNC:25805|Ensembl:ENSG00000105219|Vega:OTTHUMG00000160481 +79937 CNTNAP3 MIM:610517|HGNC:HGNC:13834|Ensembl:ENSG00000106714|Vega:OTTHUMG00000019954 +79939 SLC35E1 HGNC:HGNC:20803|Ensembl:ENSG00000127526|Vega:OTTHUMG00000152575 +79940 LINC00472 HGNC:HGNC:21380 +79943 ZNF696 HGNC:HGNC:25872|Ensembl:ENSG00000185730|Vega:OTTHUMG00000164957 +79944 L2HGDH MIM:609584|HGNC:HGNC:20499|Ensembl:ENSG00000087299|Vega:OTTHUMG00000140289 +79946 C10orf95 HGNC:HGNC:25880 +79947 DHDDS MIM:608172|HGNC:HGNC:20603|Ensembl:ENSG00000117682|Vega:OTTHUMG00000003554 +79948 PLPPR3 MIM:610391|HGNC:HGNC:23497|Ensembl:ENSG00000129951|Vega:OTTHUMG00000164523 +79949 PLEKHS1 HGNC:HGNC:26285|Ensembl:ENSG00000148735|Vega:OTTHUMG00000019074 +79953 SYNDIG1 MIM:614311|HGNC:HGNC:15885|Ensembl:ENSG00000101463|Vega:OTTHUMG00000032104 +79954 NOL10 MIM:616197|HGNC:HGNC:25862|Ensembl:ENSG00000115761|Vega:OTTHUMG00000119023 +79955 PDZD7 MIM:612971|HGNC:HGNC:26257|Ensembl:ENSG00000186862|Vega:OTTHUMG00000018916 +79956 ERMP1 MIM:611156|HGNC:HGNC:23703|Ensembl:ENSG00000099219|Vega:OTTHUMG00000019508 +79957 PAQR6 MIM:614579|HGNC:HGNC:30132|Ensembl:ENSG00000160781|Vega:OTTHUMG00000017490 +79958 DENND1C MIM:613634|HGNC:HGNC:26225|Ensembl:ENSG00000205744|Vega:OTTHUMG00000180853 +79959 CEP76 HGNC:HGNC:25727|Ensembl:ENSG00000101624|Vega:OTTHUMG00000131701 +79960 JADE1 MIM:610514|HGNC:HGNC:30027|Ensembl:ENSG00000077684|Vega:OTTHUMG00000161176 +79961 DENND2D MIM:615111|HGNC:HGNC:26192|Ensembl:ENSG00000162777|Vega:OTTHUMG00000012356 +79962 DNAJC22 HGNC:HGNC:25802|Ensembl:ENSG00000178401|Vega:OTTHUMG00000169487 +79963 ABCA11P HGNC:HGNC:31|Ensembl:ENSG00000251595 +79966 SCD5 MIM:608370|HGNC:HGNC:21088|Ensembl:ENSG00000145284|Vega:OTTHUMG00000130293 +79968 WDR76 HGNC:HGNC:25773|Ensembl:ENSG00000092470|Vega:OTTHUMG00000060143 +79969 ATAT1 MIM:615556|HGNC:HGNC:21186|Ensembl:ENSG00000137343|Vega:OTTHUMG00000031219 +79970 ZNF767P HGNC:HGNC:21884|Ensembl:ENSG00000133624 +79971 WLS MIM:611514|HGNC:HGNC:30238|Ensembl:ENSG00000116729|Vega:OTTHUMG00000009153 +79973 ZNF442 HGNC:HGNC:20877|Ensembl:ENSG00000198342|Vega:OTTHUMG00000156411 +79974 CPED1 HGNC:HGNC:26159|Ensembl:ENSG00000106034|Vega:OTTHUMG00000156982 +79977 GRHL2 MIM:608576|HGNC:HGNC:2799|Ensembl:ENSG00000083307|Vega:OTTHUMG00000149915 +79979 TRMT2B HGNC:HGNC:25748|Ensembl:ENSG00000188917|Vega:OTTHUMG00000022017 +79980 DSN1 MIM:609175|HGNC:HGNC:16165|Ensembl:ENSG00000149636|Vega:OTTHUMG00000032396 +79981 FRMD1 HGNC:HGNC:21240|Ensembl:ENSG00000153303|Vega:OTTHUMG00000016037 +79982 DNAJB14 MIM:617487|HGNC:HGNC:25881|Ensembl:ENSG00000164031|Vega:OTTHUMG00000131049 +79983 POF1B MIM:300603|HGNC:HGNC:13711|Ensembl:ENSG00000124429|Vega:OTTHUMG00000021934 +79986 ZNF702P HGNC:HGNC:25775|Ensembl:ENSG00000242779 +79987 SVEP1 MIM:611691|HGNC:HGNC:15985|Ensembl:ENSG00000165124|Vega:OTTHUMG00000020482 +79989 TTC26 MIM:617453|HGNC:HGNC:21882|Ensembl:ENSG00000105948|Vega:OTTHUMG00000157472 +79990 PLEKHH3 HGNC:HGNC:26105|Ensembl:ENSG00000068137|Vega:OTTHUMG00000180641 +79991 STN1 MIM:613128|HGNC:HGNC:26200|Ensembl:ENSG00000107960|Vega:OTTHUMG00000018996 +79992 AGPAT4-IT1 HGNC:HGNC:20988|Ensembl:ENSG00000279355 +79993 ELOVL7 MIM:614451|HGNC:HGNC:26292|Ensembl:ENSG00000164181|Vega:OTTHUMG00000162254 +79998 ANKRD53 MIM:617009|HGNC:HGNC:25691|Ensembl:ENSG00000144031|Vega:OTTHUMG00000129712 +79999 LOC79999 - +80000 GREB1L HGNC:HGNC:31042|Ensembl:ENSG00000141449|Vega:OTTHUMG00000178892 +80003 PCNX2 HGNC:HGNC:8736|Ensembl:ENSG00000135749|Vega:OTTHUMG00000037824 +80004 ESRP2 MIM:612960|HGNC:HGNC:26152|Ensembl:ENSG00000103067|Vega:OTTHUMG00000137557 +80005 DOCK5 MIM:616904|HGNC:HGNC:23476|Ensembl:ENSG00000147459|Vega:OTTHUMG00000131991 +80006 TRAPPC13 HGNC:HGNC:25828|Ensembl:ENSG00000113597|Ensembl:ENSG00000253251|Vega:OTTHUMG00000162694|Vega:OTTHUMG00000163649 +80007 C10orf88 HGNC:HGNC:25822|Ensembl:ENSG00000119965|Vega:OTTHUMG00000019190 +80008 TMEM156 HGNC:HGNC:26260|Ensembl:ENSG00000121895|Vega:OTTHUMG00000128582 +80010 RMI1 MIM:610404|HGNC:HGNC:25764|Ensembl:ENSG00000178966|Vega:OTTHUMG00000020113 +80011 FAM192A HGNC:HGNC:29856|Ensembl:ENSG00000172775|Vega:OTTHUMG00000176660 +80012 PHC3 HGNC:HGNC:15682|Ensembl:ENSG00000173889|Vega:OTTHUMG00000158777 +80013 MINDY3 MIM:611649|HGNC:HGNC:23578|Ensembl:ENSG00000148481|Vega:OTTHUMG00000017734 +80014 WWC2 HGNC:HGNC:24148|Ensembl:ENSG00000151718|Vega:OTTHUMG00000150685 +80017 C14orf159 HGNC:HGNC:20498|Ensembl:ENSG00000133943|Vega:OTTHUMG00000164980 +80018 NAA25 MIM:612755|HGNC:HGNC:25783|Ensembl:ENSG00000111300|Vega:OTTHUMG00000169638 +80019 UBTD1 MIM:616388|HGNC:HGNC:25683|Ensembl:ENSG00000165886|Vega:OTTHUMG00000018856 +80020 FOXRED2 MIM:613777|HGNC:HGNC:26264|Ensembl:ENSG00000100350|Vega:OTTHUMG00000044614 +80021 TMEM62 HGNC:HGNC:26269|Ensembl:ENSG00000137842|Vega:OTTHUMG00000176485 +80022 MYO15B HGNC:HGNC:14083|Ensembl:ENSG00000266714|Vega:OTTHUMG00000179794 +80023 NRSN2 MIM:610666|HGNC:HGNC:16229|Ensembl:ENSG00000125841|Vega:OTTHUMG00000031628 +80024 SLC8B1 MIM:609841|HGNC:HGNC:26175|Ensembl:ENSG00000089060|Vega:OTTHUMG00000169566 +80025 PANK2 MIM:606157|HGNC:HGNC:15894|Ensembl:ENSG00000125779|Vega:OTTHUMG00000031768 +80028 FBXL18 MIM:609084|HGNC:HGNC:21874|Ensembl:ENSG00000155034|Vega:OTTHUMG00000151832 +80031 SEMA6D MIM:609295|HGNC:HGNC:16770|Ensembl:ENSG00000137872|Vega:OTTHUMG00000172110 +80032 ZNF556 HGNC:HGNC:25669|Ensembl:ENSG00000172000|Vega:OTTHUMG00000180501 +80034 CSRNP3 HGNC:HGNC:30729|Ensembl:ENSG00000178662|Vega:OTTHUMG00000132145 +80035 ANP32A-IT1 HGNC:HGNC:25672 +80036 TRPM3 MIM:608961|HGNC:HGNC:17992|Ensembl:ENSG00000083067|Vega:OTTHUMG00000019997 +80039 FAM106A HGNC:HGNC:25682|Ensembl:ENSG00000213077|Vega:OTTHUMG00000179516 +80045 GPR157 HGNC:HGNC:23687|Ensembl:ENSG00000180758|Vega:OTTHUMG00000001758 +80052 RPS2P45 HGNC:HGNC:25709 +80054 CEBPA-AS1 HGNC:HGNC:25710|Ensembl:ENSG00000267296 +80055 PGAP1 MIM:611655|HGNC:HGNC:25712|Ensembl:ENSG00000197121|Vega:OTTHUMG00000132743 +80059 LRRTM4 MIM:610870|HGNC:HGNC:19411|Ensembl:ENSG00000176204|Vega:OTTHUMG00000152842 +80060 GNL3LP1 HGNC:HGNC:25733 +80063 ATF7IP2 MIM:613645|HGNC:HGNC:20397|Ensembl:ENSG00000166669|Vega:OTTHUMG00000129749 +80067 DCAF17 MIM:612515|HGNC:HGNC:25784|Ensembl:ENSG00000115827|Vega:OTTHUMG00000132259 +80069 LINC00574 HGNC:HGNC:21598|Ensembl:ENSG00000231690 +80070 ADAMTS20 MIM:611681|HGNC:HGNC:17178|Ensembl:ENSG00000173157|Vega:OTTHUMG00000169353 +80071 CCDC15 HGNC:HGNC:25798|Ensembl:ENSG00000149548|Vega:OTTHUMG00000165940 +80072 HEXA-AS1 HGNC:HGNC:25810|Ensembl:ENSG00000260339 +80078 LCAL1 HGNC:HGNC:25837 +80086 TUBA4B HGNC:HGNC:18637|Ensembl:ENSG00000243910|Vega:OTTHUMG00000154516 +80094 BIN3-IT1 HGNC:HGNC:25868 +80095 ZNF606 MIM:613905|HGNC:HGNC:25879|Ensembl:ENSG00000166704|Vega:OTTHUMG00000169804 +80097 MZT2B MIM:613450|HGNC:HGNC:25886|Ensembl:ENSG00000152082|Vega:OTTHUMG00000131625 +80099 C7orf69 HGNC:HGNC:21911 +80108 ZFP2 HGNC:HGNC:26138|Ensembl:ENSG00000198939|Vega:OTTHUMG00000130885 +80110 ZNF614 HGNC:HGNC:24722|Ensembl:ENSG00000142556|Vega:OTTHUMG00000182551 +80111 C3orf36 HGNC:HGNC:26170|Ensembl:ENSG00000221972|Vega:OTTHUMG00000187161 +80114 BICC1 MIM:614295|HGNC:HGNC:19351|Ensembl:ENSG00000122870|Vega:OTTHUMG00000018271 +80115 BAIAP2L2 MIM:617536|HGNC:HGNC:26203|Ensembl:ENSG00000128298|Vega:OTTHUMG00000151197 +80117 ARL14 MIM:614439|HGNC:HGNC:22974|Ensembl:ENSG00000179674|Vega:OTTHUMG00000159031 +80119 PIF1 MIM:610953|HGNC:HGNC:26220|Ensembl:ENSG00000140451|Vega:OTTHUMG00000132974 +80122 MAP3K19 HGNC:HGNC:26249|Ensembl:ENSG00000176601|Vega:OTTHUMG00000074083 +80124 VCPIP1 MIM:611745|HGNC:HGNC:30897|Ensembl:ENSG00000175073|Vega:OTTHUMG00000164560 +80125 CCDC33 HGNC:HGNC:26552|Ensembl:ENSG00000140481|Vega:OTTHUMG00000172621 +80127 BBOF1 HGNC:HGNC:19855|Ensembl:ENSG00000119636|Vega:OTTHUMG00000171202 +80128 TRIM46 MIM:600986|HGNC:HGNC:19019|Ensembl:ENSG00000163462|Vega:OTTHUMG00000035680 +80129 CCDC170 HGNC:HGNC:21177|Ensembl:ENSG00000120262|Vega:OTTHUMG00000015839 +80131 LRRC8E MIM:612891|HGNC:HGNC:26272|Ensembl:ENSG00000171017|Vega:OTTHUMG00000182455 +80133 MROH9 HGNC:HGNC:26287|Ensembl:ENSG00000117501|Vega:OTTHUMG00000041456 +80135 RPF1 HGNC:HGNC:30350|Ensembl:ENSG00000117133|Vega:OTTHUMG00000009857 +80139 ZNF703 MIM:617045|HGNC:HGNC:25883|Ensembl:ENSG00000183779|Vega:OTTHUMG00000164001 +80142 PTGES2 MIM:608152|HGNC:HGNC:17822|Ensembl:ENSG00000148334|Vega:OTTHUMG00000020730 +80143 SIKE1 MIM:611656|HGNC:HGNC:26119|Ensembl:ENSG00000052723|Vega:OTTHUMG00000012061 +80144 FRAS1 MIM:607830|HGNC:HGNC:19185|Ensembl:ENSG00000138759|Vega:OTTHUMG00000160856 +80145 THOC7 MIM:611965|HGNC:HGNC:29874|Ensembl:ENSG00000163634|Vega:OTTHUMG00000158767 +80146 UXS1 MIM:609749|HGNC:HGNC:17729|Ensembl:ENSG00000115652|Vega:OTTHUMG00000153150 +80148 PQLC1 HGNC:HGNC:26188|Ensembl:ENSG00000122490|Vega:OTTHUMG00000132921 +80149 ZC3H12A MIM:610562|HGNC:HGNC:26259|Ensembl:ENSG00000163874|Vega:OTTHUMG00000004221 +80150 ASRGL1 MIM:609212|HGNC:HGNC:16448|Ensembl:ENSG00000162174|Vega:OTTHUMG00000167513 +80152 CENPT MIM:611510|HGNC:HGNC:25787|Ensembl:ENSG00000102901|Vega:OTTHUMG00000173071 +80153 EDC3 MIM:609842|HGNC:HGNC:26114|Ensembl:ENSG00000179151|Vega:OTTHUMG00000142815 +80154 GOLGA2P10 HGNC:HGNC:26229 +80155 NAA15 MIM:608000|HGNC:HGNC:30782|Ensembl:ENSG00000164134|Vega:OTTHUMG00000137363 +80157 CWH43 HGNC:HGNC:26133|Ensembl:ENSG00000109182|Vega:OTTHUMG00000128627 +80161 ASMTL-AS1 HGNC:HGNC:25811 +80162 PGGHG MIM:617032|HGNC:HGNC:26210|Ensembl:ENSG00000142102|Vega:OTTHUMG00000153218 +80164 PRR36 HGNC:HGNC:26172|Ensembl:ENSG00000183248|Vega:OTTHUMG00000182504 +80167 ABHD18 HGNC:HGNC:26111|Ensembl:ENSG00000164074|Vega:OTTHUMG00000133304 +80168 MOGAT2 MIM:610270|HGNC:HGNC:23248|Ensembl:ENSG00000166391|Vega:OTTHUMG00000165341 +80169 CTC1 MIM:613129|HGNC:HGNC:26169|Ensembl:ENSG00000178971|Vega:OTTHUMG00000178443 +80173 IFT74 MIM:608040|HGNC:HGNC:21424|Ensembl:ENSG00000096872|Vega:OTTHUMG00000021028 +80174 DBF4B MIM:611661|HGNC:HGNC:17883|Ensembl:ENSG00000161692|Vega:OTTHUMG00000165717 +80176 SPSB1 MIM:611657|HGNC:HGNC:30628|Ensembl:ENSG00000171621|Vega:OTTHUMG00000001279 +80177 MYCT1 MIM:616805|HGNC:HGNC:23172|Ensembl:ENSG00000120279|Vega:OTTHUMG00000015850 +80178 C16orf59 HGNC:HGNC:25849|Ensembl:ENSG00000162062|Vega:OTTHUMG00000128859 +80179 MYO19 MIM:617379|HGNC:HGNC:26234|Ensembl:ENSG00000278259|Vega:OTTHUMG00000188437 +80183 RUBCNL HGNC:HGNC:20420|Ensembl:ENSG00000102445|Vega:OTTHUMG00000016868 +80184 CEP290 MIM:610142|HGNC:HGNC:29021|Ensembl:ENSG00000198707|Vega:OTTHUMG00000169871 +80185 TTI2 MIM:614426|HGNC:HGNC:26262|Ensembl:ENSG00000129696|Vega:OTTHUMG00000163956 +80194 TMEM134 HGNC:HGNC:26142|Ensembl:ENSG00000172663|Vega:OTTHUMG00000168034 +80195 TMEM254 HGNC:HGNC:25804|Ensembl:ENSG00000133678|Vega:OTTHUMG00000018602 +80196 RNF34 MIM:608299|HGNC:HGNC:17297|Ensembl:ENSG00000170633|Vega:OTTHUMG00000171524 +80198 MUS81 MIM:606591|HGNC:HGNC:29814|Ensembl:ENSG00000172732|Vega:OTTHUMG00000166633 +80199 FUZ MIM:610622|HGNC:HGNC:26219|Ensembl:ENSG00000010361|Vega:OTTHUMG00000167281 +80201 HKDC1 MIM:617221|HGNC:HGNC:23302|Ensembl:ENSG00000156510|Vega:OTTHUMG00000018371 +80204 FBXO11 MIM:607871|HGNC:HGNC:13590|Ensembl:ENSG00000138081|Vega:OTTHUMG00000129130 +80205 CHD9 MIM:616936|HGNC:HGNC:25701|Ensembl:ENSG00000177200|Vega:OTTHUMG00000173188 +80206 FHOD3 MIM:609691|HGNC:HGNC:26178|Ensembl:ENSG00000134775|Vega:OTTHUMG00000182381 +80207 OPA3 MIM:606580|HGNC:HGNC:8142|Ensembl:ENSG00000125741|Vega:OTTHUMG00000182125 +80208 SPG11 MIM:610844|HGNC:HGNC:11226|Ensembl:ENSG00000104133|Vega:OTTHUMG00000131199 +80209 PROSER1 HGNC:HGNC:20291|Ensembl:ENSG00000120685|Vega:OTTHUMG00000016764 +80210 ARMC9 HGNC:HGNC:20730|Ensembl:ENSG00000135931|Vega:OTTHUMG00000133229 +80212 CCDC92 HGNC:HGNC:29563|Ensembl:ENSG00000119242|Vega:OTTHUMG00000168725 +80213 TM2D3 MIM:610014|HGNC:HGNC:24128|Ensembl:ENSG00000184277|Vega:OTTHUMG00000149872 +80215 RUNX1-IT1 HGNC:HGNC:16623 +80216 ALPK1 MIM:607347|HGNC:HGNC:20917|Ensembl:ENSG00000073331|Vega:OTTHUMG00000132911 +80217 CFAP43 MIM:617558|HGNC:HGNC:26684|Ensembl:ENSG00000197748|Vega:OTTHUMG00000019002 +80218 NAA50 MIM:610834|HGNC:HGNC:29533|Ensembl:ENSG00000121579|Vega:OTTHUMG00000159294 +80219 COQ10B HGNC:HGNC:25819|Ensembl:ENSG00000115520|Vega:OTTHUMG00000132745 +80221 ACSF2 MIM:610465|HGNC:HGNC:26101|Ensembl:ENSG00000167107|Vega:OTTHUMG00000162128 +80222 TARS2 MIM:612805|HGNC:HGNC:30740|Ensembl:ENSG00000143374|Vega:OTTHUMG00000012809 +80223 RAB11FIP1 MIM:608737|HGNC:HGNC:30265|Ensembl:ENSG00000156675|Vega:OTTHUMG00000164026 +80224 NUBPL MIM:613621|HGNC:HGNC:20278|Ensembl:ENSG00000151413|Vega:OTTHUMG00000170521 +80227 PAAF1 HGNC:HGNC:25687|Ensembl:ENSG00000175575|Vega:OTTHUMG00000168062 +80228 ORAI2 MIM:610929|HGNC:HGNC:21667|Ensembl:ENSG00000160991|Vega:OTTHUMG00000157722 +80230 RUFY1 MIM:610327|HGNC:HGNC:19760|Ensembl:ENSG00000176783|Vega:OTTHUMG00000130913 +80231 CXorf21 HGNC:HGNC:25667|Ensembl:ENSG00000120280|Vega:OTTHUMG00000021325 +80232 WDR26 MIM:617424|HGNC:HGNC:21208|Ensembl:ENSG00000162923|Vega:OTTHUMG00000037636 +80233 FAAP100 MIM:611301|HGNC:HGNC:26171|Ensembl:ENSG00000185504|Vega:OTTHUMG00000167764 +80235 PIGZ MIM:611671|HGNC:HGNC:30596|Ensembl:ENSG00000119227|Vega:OTTHUMG00000155522 +80237 ELL3 MIM:609885|HGNC:HGNC:23113|Ensembl:ENSG00000128886|Vega:OTTHUMG00000059936 +80243 PREX2 MIM:612139|HGNC:HGNC:22950|Ensembl:ENSG00000046889|Vega:OTTHUMG00000164402 +80254 CEP63 MIM:614724|HGNC:HGNC:25815|Ensembl:ENSG00000182923|Vega:OTTHUMG00000159725 +80255 SLC35F5 HGNC:HGNC:23617|Ensembl:ENSG00000115084|Vega:OTTHUMG00000131361 +80256 FAM214B HGNC:HGNC:25666|Ensembl:ENSG00000005238|Vega:OTTHUMG00000019847 +80258 EFHC2 MIM:300817|HGNC:HGNC:26233|Ensembl:ENSG00000183690|Vega:OTTHUMG00000021393 +80262 C16orf70 HGNC:HGNC:29564|Ensembl:ENSG00000125149|Vega:OTTHUMG00000137510 +80263 TRIM45 MIM:609318|HGNC:HGNC:19018|Ensembl:ENSG00000134253|Vega:OTTHUMG00000012119 +80264 ZNF430 HGNC:HGNC:20808|Ensembl:ENSG00000118620|Vega:OTTHUMG00000182771 +80267 EDEM3 MIM:610214|HGNC:HGNC:16787|Ensembl:ENSG00000116406|Vega:OTTHUMG00000035387 +80270 HSD3B7 MIM:607764|HGNC:HGNC:18324|Ensembl:ENSG00000099377|Vega:OTTHUMG00000132417 +80271 ITPKC MIM:606476|HGNC:HGNC:14897|Ensembl:ENSG00000086544|Vega:OTTHUMG00000182688 +80273 GRPEL1 MIM:606173|HGNC:HGNC:19696|Ensembl:ENSG00000109519|Vega:OTTHUMG00000090495 +80274 SCUBE1 MIM:611746|HGNC:HGNC:13441|Ensembl:ENSG00000159307|Vega:OTTHUMG00000150679 +80279 CDK5RAP3 MIM:608202|HGNC:HGNC:18673|Ensembl:ENSG00000108465|Vega:OTTHUMG00000178682 +80298 MTERF2 MIM:616929|HGNC:HGNC:30779|Ensembl:ENSG00000120832|Vega:OTTHUMG00000170007 +80301 PLEKHO2 HGNC:HGNC:30026|Ensembl:ENSG00000241839|Vega:OTTHUMG00000133050 +80303 EFHD1 MIM:611617|HGNC:HGNC:29556|Ensembl:ENSG00000115468|Vega:OTTHUMG00000133263 +80304 WDCP MIM:616234|HGNC:HGNC:26157|Ensembl:ENSG00000163026|Vega:OTTHUMG00000125498 +80305 TRABD HGNC:HGNC:28805|Ensembl:ENSG00000170638|Vega:OTTHUMG00000044644 +80306 MED28 MIM:610311|HGNC:HGNC:24628|Ensembl:ENSG00000118579|Vega:OTTHUMG00000161980 +80307 FER1L4 HGNC:HGNC:15801|Ensembl:ENSG00000088340 +80308 FLAD1 MIM:610595|HGNC:HGNC:24671|Ensembl:ENSG00000160688|Vega:OTTHUMG00000037416 +80309 SPHKAP MIM:611646|HGNC:HGNC:30619|Ensembl:ENSG00000153820|Vega:OTTHUMG00000153584 +80310 PDGFD MIM:609673|HGNC:HGNC:30620|Ensembl:ENSG00000170962|Vega:OTTHUMG00000165953 +80311 KLHL15 MIM:300980|HGNC:HGNC:29347|Ensembl:ENSG00000174010|Vega:OTTHUMG00000021261 +80312 TET1 MIM:607790|HGNC:HGNC:29484|Ensembl:ENSG00000138336|Vega:OTTHUMG00000018359 +80313 LRRC27 HGNC:HGNC:29346|Ensembl:ENSG00000148814|Vega:OTTHUMG00000019284 +80314 EPC1 MIM:610999|HGNC:HGNC:19876|Ensembl:ENSG00000120616|Vega:OTTHUMG00000017925 +80315 CPEB4 MIM:610607|HGNC:HGNC:21747|Ensembl:ENSG00000113742|Vega:OTTHUMG00000130541 +80316 PPP1R2P9 HGNC:HGNC:16324|Ensembl:ENSG00000102055|Vega:OTTHUMG00000021382 +80317 ZKSCAN3 MIM:612791|HGNC:HGNC:13853|Ensembl:ENSG00000189298|Vega:OTTHUMG00000014521 +80318 GKAP1 MIM:611356|HGNC:HGNC:17496|Ensembl:ENSG00000165113|Vega:OTTHUMG00000020106 +80319 CXXC4 MIM:611645|HGNC:HGNC:24593|Ensembl:ENSG00000168772|Vega:OTTHUMG00000131121 +80320 SP6 MIM:608613|HGNC:HGNC:14530|Ensembl:ENSG00000189120|Vega:OTTHUMG00000132067 +80321 CEP70 MIM:614310|HGNC:HGNC:29972|Ensembl:ENSG00000114107|Vega:OTTHUMG00000159891 +80323 CCDC68 MIM:616909|HGNC:HGNC:24350|Ensembl:ENSG00000166510|Vega:OTTHUMG00000132708 +80324 PUS1 MIM:608109|HGNC:HGNC:15508|Ensembl:ENSG00000177192|Vega:OTTHUMG00000128507 +80325 ABTB1 MIM:608308|HGNC:HGNC:18275|Ensembl:ENSG00000114626|Vega:OTTHUMG00000159636 +80326 WNT10A MIM:606268|HGNC:HGNC:13829|Ensembl:ENSG00000135925|Vega:OTTHUMG00000133085 +80327 MAPRE1P1 HGNC:HGNC:29624 +80328 ULBP2 MIM:605698|HGNC:HGNC:14894|Ensembl:ENSG00000131015|Vega:OTTHUMG00000015803 +80329 ULBP1 MIM:605697|HGNC:HGNC:14893|Ensembl:ENSG00000111981|Vega:OTTHUMG00000015810 +80331 DNAJC5 MIM:611203|HGNC:HGNC:16235|Ensembl:ENSG00000101152|Vega:OTTHUMG00000033007 +80332 ADAM33 MIM:607114|HGNC:HGNC:15478|Ensembl:ENSG00000149451|Vega:OTTHUMG00000031758 +80333 KCNIP4 MIM:608182|HGNC:HGNC:30083|Ensembl:ENSG00000185774|Vega:OTTHUMG00000128557 +80335 WDR82 MIM:611059|HGNC:HGNC:28826|Ensembl:ENSG00000164091|Vega:OTTHUMG00000150391 +80336 PABPC1L HGNC:HGNC:15797|Ensembl:ENSG00000101104|Vega:OTTHUMG00000032553 +80339 PNPLA3 MIM:609567|HGNC:HGNC:18590|Ensembl:ENSG00000100344|Vega:OTTHUMG00000150555 +80341 BPIFB2 MIM:614108|HGNC:HGNC:16177|Ensembl:ENSG00000078898|Vega:OTTHUMG00000032232 +80342 TRAF3IP3 MIM:608255|HGNC:HGNC:30766|Ensembl:ENSG00000009790|Vega:OTTHUMG00000036480 +80343 SEL1L2 MIM:614289|HGNC:HGNC:15897|Ensembl:ENSG00000101251|Vega:OTTHUMG00000031910 +80344 DCAF11 MIM:613317|HGNC:HGNC:20258|Ensembl:ENSG00000100897|Vega:OTTHUMG00000028793 +80345 ZSCAN16 HGNC:HGNC:20813|Ensembl:ENSG00000196812|Vega:OTTHUMG00000014509 +80346 REEP4 MIM:609349|HGNC:HGNC:26176|Ensembl:ENSG00000168476|Vega:OTTHUMG00000131491 +80347 COASY MIM:609855|HGNC:HGNC:29932|Ensembl:ENSG00000068120|Vega:OTTHUMG00000180245 +80349 WDR61 MIM:609540|HGNC:HGNC:30300|Ensembl:ENSG00000140395|Vega:OTTHUMG00000143735 +80350 LPAL2 MIM:611682|HGNC:HGNC:21210|Ensembl:ENSG00000213071 +80351 TNKS2 MIM:607128|HGNC:HGNC:15677|Ensembl:ENSG00000107854|Vega:OTTHUMG00000018747 +80352 RNF39 MIM:607524|HGNC:HGNC:18064|Ensembl:ENSG00000204618|Vega:OTTHUMG00000031288 +80380 PDCD1LG2 MIM:605723|HGNC:HGNC:18731|Ensembl:ENSG00000197646|Vega:OTTHUMG00000019504 +80381 CD276 MIM:605715|HGNC:HGNC:19137|Ensembl:ENSG00000103855|Vega:OTTHUMG00000137585 +80700 UBXN6 MIM:611946|HGNC:HGNC:14928|Ensembl:ENSG00000167671|Vega:OTTHUMG00000181954 +80701 AKR1D1P1 HGNC:HGNC:11288 +80704 SLC19A3 MIM:606152|HGNC:HGNC:16266|Ensembl:ENSG00000135917|Vega:OTTHUMG00000133185 +80705 TSGA10 MIM:607166|HGNC:HGNC:14927|Ensembl:ENSG00000135951|Vega:OTTHUMG00000130637 +80709 AKNA MIM:605729|HGNC:HGNC:24108|Ensembl:ENSG00000106948|Vega:OTTHUMG00000020538 +80712 ESX1 MIM:300154|HGNC:HGNC:14865|Ensembl:ENSG00000123576|Vega:OTTHUMG00000022125 +80713 MTIF2P1 HGNC:HGNC:14861 +80714 PBX4 MIM:608127|HGNC:HGNC:13403|Ensembl:ENSG00000105717|Vega:OTTHUMG00000172310 +80723 SLC35G2 HGNC:HGNC:28480|Ensembl:ENSG00000168917|Vega:OTTHUMG00000159787 +80724 ACAD10 MIM:611181|HGNC:HGNC:21597|Ensembl:ENSG00000111271|Vega:OTTHUMG00000169602 +80725 SRCIN1 MIM:610786|HGNC:HGNC:29506|Ensembl:ENSG00000277363|Vega:OTTHUMG00000188493 +80726 KIAA1683 HGNC:HGNC:29350|Ensembl:ENSG00000130518|Vega:OTTHUMG00000183354 +80727 TTYH3 MIM:608919|HGNC:HGNC:22222|Ensembl:ENSG00000136295|Vega:OTTHUMG00000152050 +80728 ARHGAP39 MIM:615880|HGNC:HGNC:29351|Ensembl:ENSG00000147799|Vega:OTTHUMG00000165182 +80731 THSD7B HGNC:HGNC:29348|Ensembl:ENSG00000144229|Vega:OTTHUMG00000153590 +80736 SLC44A4 MIM:606107|HGNC:HGNC:13941|Ensembl:ENSG00000204385|Vega:OTTHUMG00000031133 +80737 VWA7 MIM:609693|HGNC:HGNC:13939|Ensembl:ENSG00000204396|Vega:OTTHUMG00000031132 +80739 MPIG6B MIM:606520|HGNC:HGNC:13937|Ensembl:ENSG00000204420|Vega:OTTHUMG00000031130 +80740 LY6G6C MIM:610435|HGNC:HGNC:13936|Ensembl:ENSG00000204421|Vega:OTTHUMG00000031251 +80741 LY6G5C MIM:610434|HGNC:HGNC:13932|Ensembl:ENSG00000204428|Vega:OTTHUMG00000031228 +80742 PRR3 HGNC:HGNC:21149|Ensembl:ENSG00000204576|Vega:OTTHUMG00000031037 +80745 THUMPD2 MIM:611751|HGNC:HGNC:14890|Ensembl:ENSG00000138050|Vega:OTTHUMG00000102149 +80746 TSEN2 MIM:608753|HGNC:HGNC:28422|Ensembl:ENSG00000154743|Vega:OTTHUMG00000129765 +80755 AARSD1 MIM:613212|HGNC:HGNC:28417|Ensembl:ENSG00000266967|Vega:OTTHUMG00000153515 +80757 TMEM121 HGNC:HGNC:20511|Ensembl:ENSG00000184986|Vega:OTTHUMG00000029912 +80758 PRR7 HGNC:HGNC:28130|Ensembl:ENSG00000131188|Vega:OTTHUMG00000130861 +80759 KHDC1 MIM:611688|HGNC:HGNC:21366|Ensembl:ENSG00000135314|Vega:OTTHUMG00000015030 +80760 ITIH5 MIM:609783|HGNC:HGNC:21449|Ensembl:ENSG00000123243|Vega:OTTHUMG00000017635 +80762 NDFIP1 MIM:612050|HGNC:HGNC:17592|Ensembl:ENSG00000131507|Vega:OTTHUMG00000129659 +80763 SPX HGNC:HGNC:28139|Ensembl:ENSG00000134548|Vega:OTTHUMG00000169134 +80764 THAP7 MIM:609518|HGNC:HGNC:23190|Ensembl:ENSG00000184436|Vega:OTTHUMG00000150879 +80765 STARD5 MIM:607050|HGNC:HGNC:18065|Ensembl:ENSG00000172345|Vega:OTTHUMG00000147342 +80767 MMDFS MIM:605711 +80768 HMNJ MIM:605726 +80770 CTRCT25 MIM:605728 +80771 MCOPCB2 MIM:605738 +80772 CPTP MIM:615467|HGNC:HGNC:28116|Ensembl:ENSG00000224051|Vega:OTTHUMG00000003171 +80774 LIMD2 HGNC:HGNC:28142|Ensembl:ENSG00000136490|Vega:OTTHUMG00000178907 +80775 TMEM177 HGNC:HGNC:28143|Ensembl:ENSG00000144120|Vega:OTTHUMG00000153312 +80776 B9D2 MIM:611951|HGNC:HGNC:28636|Ensembl:ENSG00000123810|Vega:OTTHUMG00000182758 +80777 CYB5B MIM:611964|HGNC:HGNC:24374|Ensembl:ENSG00000103018|Vega:OTTHUMG00000133020 +80778 ZNF34 MIM:194526|HGNC:HGNC:13098|Ensembl:ENSG00000196378|Vega:OTTHUMG00000165248 +80781 COL18A1 MIM:120328|HGNC:HGNC:2195|Ensembl:ENSG00000182871|Vega:OTTHUMG00000090407 +80789 INTS5 MIM:611349|HGNC:HGNC:29352|Ensembl:ENSG00000185085|Vega:OTTHUMG00000167605 +80790 CMIP MIM:610112|HGNC:HGNC:24319|Ensembl:ENSG00000153815|Vega:OTTHUMG00000176520 +80816 ASXL3 MIM:615115|HGNC:HGNC:29357|Ensembl:ENSG00000141431|Vega:OTTHUMG00000178395 +80817 CEP44 HGNC:HGNC:29356|Ensembl:ENSG00000164118|Vega:OTTHUMG00000160752 +80818 ZNF436 MIM:611703|HGNC:HGNC:20814|Ensembl:ENSG00000125945|Vega:OTTHUMG00000003232 +80820 EEPD1 MIM:617192|HGNC:HGNC:22223|Ensembl:ENSG00000122547|Vega:OTTHUMG00000154904 +80821 DDHD1 MIM:614603|HGNC:HGNC:19714|Ensembl:ENSG00000100523|Vega:OTTHUMG00000140305 +80823 BHLHB9 MIM:300921|HGNC:HGNC:29353|Ensembl:ENSG00000198908|Vega:OTTHUMG00000022060 +80824 DUSP16 MIM:607175|HGNC:HGNC:17909|Ensembl:ENSG00000111266 +80829 ZFP91 HGNC:HGNC:14983|Ensembl:ENSG00000186660|Ensembl:ENSG00000255073|Vega:OTTHUMG00000137391|Vega:OTTHUMG00000166280 +80830 APOL6 MIM:607256|HGNC:HGNC:14870|Ensembl:ENSG00000221963|Vega:OTTHUMG00000150615 +80831 APOL5 MIM:607255|HGNC:HGNC:14869|Ensembl:ENSG00000128313|Vega:OTTHUMG00000150588 +80832 APOL4 MIM:607254|HGNC:HGNC:14867|Ensembl:ENSG00000100336|Vega:OTTHUMG00000150630 +80833 APOL3 MIM:607253|HGNC:HGNC:14868|Ensembl:ENSG00000128284|Vega:OTTHUMG00000150632 +80834 TAS1R2 MIM:606226|HGNC:HGNC:14905|Ensembl:ENSG00000179002|Vega:OTTHUMG00000002442 +80835 TAS1R1 MIM:606225|HGNC:HGNC:14448|Ensembl:ENSG00000173662|Vega:OTTHUMG00000001441 +80851 SH3BP5L HGNC:HGNC:29360|Ensembl:ENSG00000175137|Vega:OTTHUMG00000040389 +80852 GRIP2 HGNC:HGNC:23841|Ensembl:ENSG00000144596|Vega:OTTHUMG00000155544 +80853 KDM7A HGNC:HGNC:22224|Ensembl:ENSG00000006459|Vega:OTTHUMG00000157327 +80854 SETD7 MIM:606594|HGNC:HGNC:30412|Ensembl:ENSG00000145391|Vega:OTTHUMG00000133385 +80856 LNPK MIM:610236|HGNC:HGNC:21610|Ensembl:ENSG00000144320|Vega:OTTHUMG00000154112 +80862 ZNRD1ASP MIM:615714|HGNC:HGNC:13924|Ensembl:ENSG00000204623 +80863 PRRT1 HGNC:HGNC:13943|Ensembl:ENSG00000204314|Vega:OTTHUMG00000031144 +80864 EGFL8 MIM:609897|HGNC:HGNC:13944|Ensembl:ENSG00000241404|Vega:OTTHUMG00000031222 +80868 HCG4B HGNC:HGNC:22919 +80870 DKBI MIM:127600 +80871 ANMA MIM:605746 +80895 ILKAP HGNC:HGNC:15566|Ensembl:ENSG00000132323|Vega:OTTHUMG00000133334 +80896 NPL MIM:611412|HGNC:HGNC:16781|Ensembl:ENSG00000135838|Vega:OTTHUMG00000035321 +80975 TMPRSS5 MIM:606751|HGNC:HGNC:14908|Ensembl:ENSG00000166682|Vega:OTTHUMG00000168186 +81025 GJA9 MIM:611923|HGNC:HGNC:19155|Ensembl:ENSG00000131233|Vega:OTTHUMG00000000482 +81027 TUBB1 MIM:612901|HGNC:HGNC:16257|Ensembl:ENSG00000101162|Vega:OTTHUMG00000032860 +81029 WNT5B MIM:606361|HGNC:HGNC:16265|Ensembl:ENSG00000111186|Vega:OTTHUMG00000090375 +81030 ZBP1 MIM:606750|HGNC:HGNC:16176|Ensembl:ENSG00000124256|Vega:OTTHUMG00000032824 +81031 SLC2A10 MIM:606145|HGNC:HGNC:13444|Ensembl:ENSG00000197496|Vega:OTTHUMG00000032657 +81033 KCNH6 MIM:608168|HGNC:HGNC:18862|Ensembl:ENSG00000173826|Vega:OTTHUMG00000178901 +81034 SLC25A32 MIM:610815|HGNC:HGNC:29683|Ensembl:ENSG00000164933|Vega:OTTHUMG00000164790 +81035 COLEC12 MIM:607621|HGNC:HGNC:16016|Ensembl:ENSG00000158270|Vega:OTTHUMG00000178145 +81037 CLPTM1L MIM:612585|HGNC:HGNC:24308|Ensembl:ENSG00000049656|Vega:OTTHUMG00000131015 +81047 OR5BJ1P HGNC:HGNC:15434 +81050 OR5AC2 HGNC:HGNC:15431|Ensembl:ENSG00000196578|Vega:OTTHUMG00000160083 +81061 OR11H1 HGNC:HGNC:15404|Ensembl:ENSG00000130538|Vega:OTTHUMG00000030069 +81075 OR5BH1P HGNC:HGNC:15407 +81076 OR5AW1P HGNC:HGNC:15406 +81077 OR4W1P HGNC:HGNC:15405 +81078 OR4K12P HGNC:HGNC:15403 +81079 OR4K11P HGNC:HGNC:15402 +81081 OR7A18P HGNC:HGNC:15399 +81090 OR1AB1P HGNC:HGNC:15390 +81099 OR4F17 HGNC:HGNC:15381|Ensembl:ENSG00000176695|Vega:OTTHUMG00000180454 +81104 OR4Q1P HGNC:HGNC:15376 +81109 OR11K1P HGNC:HGNC:15371 +81110 OR11J2P HGNC:HGNC:15370 +81111 OR11J1P HGNC:HGNC:15369 +81113 OR11H3P HGNC:HGNC:15367 +81114 OR7K1P HGNC:HGNC:15366 +81115 OR7E106P HGNC:HGNC:15365 +81116 OR7E105P HGNC:HGNC:15364 +81126 OR4K16P HGNC:HGNC:15354 +81127 OR4K15 HGNC:HGNC:15353|Ensembl:ENSG00000169488|Vega:OTTHUMG00000170635 +81136 OR7E111P HGNC:HGNC:15344 +81137 OR7E104P HGNC:HGNC:15343 +81138 OR7E101P HGNC:HGNC:15342 +81140 OR9R1P HGNC:HGNC:15340 +81153 OR9M1P HGNC:HGNC:15327 +81155 OR9I3P HGNC:HGNC:15325 +81156 OR9I2P HGNC:HGNC:15324 +81159 OR9G3P HGNC:HGNC:15321 +81160 OR9G2P HGNC:HGNC:15320 +81162 OR8R1P HGNC:HGNC:15318 +81163 OR8Q1P HGNC:HGNC:15317 +81164 OR8L1P HGNC:HGNC:15316 +81166 OR8K4P HGNC:HGNC:15314 +81168 OR8J3 HGNC:HGNC:15312|Ensembl:ENSG00000167822|Vega:OTTHUMG00000166834 +81169 OR8J2 HGNC:HGNC:15311|Vega:OTTHUMG00000166850 +81175 OR7E128P HGNC:HGNC:15305 +81176 OR7E126P HGNC:HGNC:15304 +81182 OR5W1P HGNC:HGNC:15298 +81185 OR5P4P HGNC:HGNC:15295 +81187 OR5M13P HGNC:HGNC:15293 +81188 OR5M12P HGNC:HGNC:15292 +81191 OR5G5P HGNC:HGNC:15289 +81192 OR5G4P HGNC:HGNC:15288 +81193 OR5G3 HGNC:HGNC:15287|Vega:OTTHUMG00000154395 +81194 OR5F2P HGNC:HGNC:15286 +81196 OR5D17P HGNC:HGNC:15284 +81198 OR5D15P HGNC:HGNC:15282 +81201 OR5BR1P HGNC:HGNC:15279 +81202 OR5BQ1P HGNC:HGNC:15278 +81203 OR5BP1P HGNC:HGNC:15277 +81204 OR5BN1P HGNC:HGNC:15276 +81205 OR5BL1P HGNC:HGNC:15275 +81207 OR5BE1P HGNC:HGNC:15273 +81208 OR5BC1P HGNC:HGNC:15272 +81209 OR5BB1P HGNC:HGNC:15271 +81210 OR5BA1P HGNC:HGNC:15270 +81211 OR5B19P HGNC:HGNC:15269 +81215 OR5B15P HGNC:HGNC:15265 +81221 OR5AQ1P HGNC:HGNC:15259 +81223 OR5AP1P HGNC:HGNC:15257 +81224 OR5AN2P HGNC:HGNC:15256 +81226 OR5AM1P HGNC:HGNC:15254 +81228 OR5AK3P HGNC:HGNC:15252 +81230 OR5AK1P HGNC:HGNC:15250 +81236 OR56A7P HGNC:HGNC:15244 +81240 OR52Y1P HGNC:HGNC:15240 +81242 OR52V1P HGNC:HGNC:15238 +81243 OR52U1P HGNC:HGNC:15237 +81244 OR52T1P HGNC:HGNC:15236 +81246 OR52Q1P HGNC:HGNC:15234 +81248 OR52P1P HGNC:HGNC:15232 +81251 OR52N3P HGNC:HGNC:15229 +81261 OR52H2P HGNC:HGNC:15219 +81264 OR52E7P HGNC:HGNC:15216 +81270 OR52B5P HGNC:HGNC:15210 +81274 OR52B1P HGNC:HGNC:15206 +81278 OR51K1P HGNC:HGNC:15202 +81282 OR51G2 HGNC:HGNC:15198|Ensembl:ENSG00000176893|Vega:OTTHUMG00000066501 +81285 OR51E2 MIM:611268|HGNC:HGNC:15195|Ensembl:ENSG00000167332|Vega:OTTHUMG00000133362 +81295 OR51A10P HGNC:HGNC:15185 +81298 OR4R3P HGNC:HGNC:15182 +81299 OR4R2P HGNC:HGNC:15181 +81300 OR4P4 HGNC:HGNC:15180|Ensembl:ENSG00000181927|Vega:OTTHUMG00000165300 +81304 OR4D7P HGNC:HGNC:15176 +81309 OR4C15 HGNC:HGNC:15171|Ensembl:ENSG00000181939|Vega:OTTHUMG00000166714 +81310 OR4C14P HGNC:HGNC:15170 +81315 OR4A8 HGNC:HGNC:15165|Vega:OTTHUMG00000154245 +81316 OR4A7P HGNC:HGNC:15164 +81318 OR4A5 HGNC:HGNC:15162|Ensembl:ENSG00000221840|Vega:OTTHUMG00000166764 +81320 OR4A3P HGNC:HGNC:15160 +81322 OR4A21P HGNC:HGNC:15158 +81324 OR4A19P HGNC:HGNC:15156 +81325 OR4A18P HGNC:HGNC:15155 +81327 OR4A16 HGNC:HGNC:15153|Ensembl:ENSG00000181961|Vega:OTTHUMG00000166710 +81328 OR4A15 HGNC:HGNC:15152|Ensembl:ENSG00000181958|Vega:OTTHUMG00000166711 +81329 OR4A14P HGNC:HGNC:15151 +81330 OR4A13P HGNC:HGNC:15150 +81331 OR4A12P HGNC:HGNC:15149 +81336 OR2AH1P HGNC:HGNC:15144 +81340 OR10Y1P HGNC:HGNC:15140 +81341 OR10W1 HGNC:HGNC:15139|Ensembl:ENSG00000172772|Vega:OTTHUMG00000167462 +81342 OR10V3P HGNC:HGNC:15138 +81343 OR10V2P HGNC:HGNC:15137|Ensembl:ENSG00000255538 +81345 OR10Q2P HGNC:HGNC:15135 +81352 OR7M1P HGNC:HGNC:15128 +81353 OR7E115P HGNC:HGNC:15127 +81354 OR7E110P HGNC:HGNC:15126 +81356 OR6L2P HGNC:HGNC:15125 +81358 OR7E116P HGNC:HGNC:15122 +81363 OR7E108P HGNC:HGNC:15117 +81366 OR2AM1P HGNC:HGNC:15113 +81377 OR13C7 HGNC:HGNC:15102|Vega:OTTHUMG00000019893 +81382 OR9P1P HGNC:HGNC:15097 +81383 OR9N1P HGNC:HGNC:15096 +81390 OR4F7P HGNC:HGNC:15089 +81392 OR2AE1 HGNC:HGNC:15087|Ensembl:ENSG00000244623|Vega:OTTHUMG00000156650 +81399 OR4F16 HGNC:HGNC:15079|Ensembl:ENSG00000273547|Vega:OTTHUMG00000002581 +81406 OR2W6P HGNC:HGNC:15072 +81407 OR2W4P HGNC:HGNC:15071 +81419 OR7E99P HGNC:HGNC:15059 +81421 OR5M14P HGNC:HGNC:15057 +81428 OR7E122P HGNC:HGNC:15050 +81430 OR7E100P HGNC:HGNC:15048 +81431 OR5AC1 HGNC:HGNC:15047|Vega:OTTHUMG00000154300 +81438 OR4G6P HGNC:HGNC:15039 +81439 OR9H1P HGNC:HGNC:15038 +81440 OR6R1P HGNC:HGNC:15037 +81442 OR6N2 HGNC:HGNC:15035|Ensembl:ENSG00000188340|Vega:OTTHUMG00000022775 +81448 OR6K2 HGNC:HGNC:15029|Ensembl:ENSG00000196171|Vega:OTTHUMG00000022768 +81449 OR6K1P HGNC:HGNC:15028 +81458 OR2T7 HGNC:HGNC:15019 +81462 OR2L9P HGNC:HGNC:15015 +81465 OR2L6P HGNC:HGNC:15012 +81466 OR2L5 HGNC:HGNC:15011|Ensembl:ENSG00000197454|Vega:OTTHUMG00000040194 +81469 OR2G3 HGNC:HGNC:15008|Ensembl:ENSG00000177476|Vega:OTTHUMG00000040576 +81470 OR2G2 HGNC:HGNC:15007|Ensembl:ENSG00000177489|Vega:OTTHUMG00000040575 +81472 OR2C3 HGNC:HGNC:15005|Ensembl:ENSG00000196242|Vega:OTTHUMG00000040579 +81473 OR2AS1P HGNC:HGNC:15004 +81474 OR2AQ1P HGNC:HGNC:15003 +81479 OR11I1P HGNC:HGNC:14997 +81486 OR10AE1P HGNC:HGNC:14990 +81487 OR10AA1P HGNC:HGNC:14989 +81488 POLR2M MIM:606485|HGNC:HGNC:14862|Ensembl:ENSG00000255529|Vega:OTTHUMG00000166486 +81490 PTDSS2 MIM:612793|HGNC:HGNC:15463|Ensembl:ENSG00000174915|Vega:OTTHUMG00000119087 +81491 GPR63 MIM:606915|HGNC:HGNC:13302|Ensembl:ENSG00000112218|Vega:OTTHUMG00000015245 +81492 RSPH6A MIM:607548|HGNC:HGNC:14241|Ensembl:ENSG00000104941|Vega:OTTHUMG00000182482 +81493 SYNC MIM:611750|HGNC:HGNC:28897|Ensembl:ENSG00000162520|Vega:OTTHUMG00000008087 +81494 CFHR5 MIM:608593|HGNC:HGNC:24668|Ensembl:ENSG00000134389|Vega:OTTHUMG00000036517 +81501 DCSTAMP MIM:605933|HGNC:HGNC:18549|Ensembl:ENSG00000164935|Vega:OTTHUMG00000164890 +81502 HM13 MIM:607106|HGNC:HGNC:16435|Ensembl:ENSG00000101294|Vega:OTTHUMG00000032175 +81532 MOB2 MIM:611969|HGNC:HGNC:24904|Ensembl:ENSG00000182208|Vega:OTTHUMG00000165545 +81533 ITFG1 MIM:611803|HGNC:HGNC:30697|Ensembl:ENSG00000129636|Vega:OTTHUMG00000133103 +81537 SGPP1 MIM:612826|HGNC:HGNC:17720|Ensembl:ENSG00000126821|Vega:OTTHUMG00000029080 +81539 SLC38A1 MIM:608490|HGNC:HGNC:13447|Ensembl:ENSG00000111371|Vega:OTTHUMG00000169470 +81542 TMX1 MIM:610527|HGNC:HGNC:15487|Ensembl:ENSG00000139921|Vega:OTTHUMG00000171003 +81543 LRRC3 HGNC:HGNC:14965|Ensembl:ENSG00000160233|Vega:OTTHUMG00000040847 +81544 GDPD5 MIM:609632|HGNC:HGNC:28804|Ensembl:ENSG00000158555|Vega:OTTHUMG00000165484 +81545 FBXO38 MIM:608533|HGNC:HGNC:28844|Ensembl:ENSG00000145868|Vega:OTTHUMG00000129929 +81550 TDRD3 MIM:614392|HGNC:HGNC:20612|Ensembl:ENSG00000083544|Vega:OTTHUMG00000017007 +81551 STMN4 HGNC:HGNC:16078|Ensembl:ENSG00000015592|Vega:OTTHUMG00000099461 +81552 VOPP1 MIM:611915|HGNC:HGNC:34518|Ensembl:ENSG00000154978|Vega:OTTHUMG00000156124 +81553 FAM49A HGNC:HGNC:25373|Ensembl:ENSG00000197872|Vega:OTTHUMG00000090615 +81554 RCC1L HGNC:HGNC:14948|Ensembl:ENSG00000274523|Vega:OTTHUMG00000130373 +81555 YIPF5 MIM:611483|HGNC:HGNC:24877|Ensembl:ENSG00000145817|Vega:OTTHUMG00000129679 +81556 INTS14 HGNC:HGNC:25372|Ensembl:ENSG00000138614|Vega:OTTHUMG00000133159 +81557 MAGED4B MIM:300765|HGNC:HGNC:22880|Ensembl:ENSG00000187243|Vega:OTTHUMG00000021546 +81558 FAM117A HGNC:HGNC:24179|Ensembl:ENSG00000121104|Vega:OTTHUMG00000161696 +81559 TRIM11 MIM:607868|HGNC:HGNC:16281|Ensembl:ENSG00000154370|Vega:OTTHUMG00000039773 +81562 LMAN2L MIM:609552|HGNC:HGNC:19263|Ensembl:ENSG00000114988|Vega:OTTHUMG00000130453 +81563 C1orf21 HGNC:HGNC:15494|Ensembl:ENSG00000116667|Vega:OTTHUMG00000035386 +81565 NDEL1 MIM:607538|HGNC:HGNC:17620|Ensembl:ENSG00000166579|Vega:OTTHUMG00000108193 +81566 CSRNP2 HGNC:HGNC:16006|Ensembl:ENSG00000110925|Vega:OTTHUMG00000169578 +81567 TXNDC5 MIM:616412|HGNC:HGNC:21073|Ensembl:ENSG00000239264|Vega:OTTHUMG00000014216 +81569 ACTL8 HGNC:HGNC:24018|Ensembl:ENSG00000117148|Vega:OTTHUMG00000002512 +81570 CLPB MIM:616254|HGNC:HGNC:30664|Ensembl:ENSG00000162129|Vega:OTTHUMG00000167902 +81571 MIR600HG HGNC:HGNC:23642|Ensembl:ENSG00000236901 +81572 PDRG1 MIM:610789|HGNC:HGNC:16119|Ensembl:ENSG00000088356|Vega:OTTHUMG00000032196 +81573 ANKRD13C MIM:615125|HGNC:HGNC:25374|Ensembl:ENSG00000118454|Vega:OTTHUMG00000009343 +81575 APOLD1 MIM:612456|HGNC:HGNC:25268|Ensembl:ENSG00000178878|Vega:OTTHUMG00000153561 +81576 CCDC130 HGNC:HGNC:28118|Ensembl:ENSG00000104957|Vega:OTTHUMG00000180837 +81577 GFOD2 HGNC:HGNC:28159|Ensembl:ENSG00000141098|Vega:OTTHUMG00000137537 +81578 COL21A1 MIM:610002|HGNC:HGNC:17025|Ensembl:ENSG00000124749|Vega:OTTHUMG00000014907 +81579 PLA2G12A MIM:611652|HGNC:HGNC:18554|Ensembl:ENSG00000123739|Vega:OTTHUMG00000131915 +81602 CDADC1 HGNC:HGNC:20299|Ensembl:ENSG00000102543|Vega:OTTHUMG00000016913 +81603 TRIM8 MIM:606125|HGNC:HGNC:15579|Ensembl:ENSG00000171206|Vega:OTTHUMG00000018964 +81605 URM1 MIM:612693|HGNC:HGNC:28378|Ensembl:ENSG00000167118|Vega:OTTHUMG00000020742 +81606 LBH MIM:611763|HGNC:HGNC:29532|Ensembl:ENSG00000213626|Vega:OTTHUMG00000152051 +81607 NECTIN4 MIM:609607|HGNC:HGNC:19688|Ensembl:ENSG00000143217|Vega:OTTHUMG00000031475 +81608 FIP1L1 MIM:607686|HGNC:HGNC:19124|Ensembl:ENSG00000145216|Vega:OTTHUMG00000128701 +81609 SNX27 MIM:611541|HGNC:HGNC:20073|Ensembl:ENSG00000143376|Vega:OTTHUMG00000013052 +81610 FAM83D HGNC:HGNC:16122|Ensembl:ENSG00000101447|Vega:OTTHUMG00000032462 +81611 ANP32E MIM:609611|HGNC:HGNC:16673|Ensembl:ENSG00000143401|Vega:OTTHUMG00000012547 +81614 NIPA2 MIM:608146|HGNC:HGNC:17044|Ensembl:ENSG00000140157|Vega:OTTHUMG00000129101 +81615 TMEM163 HGNC:HGNC:25380|Ensembl:ENSG00000152128|Vega:OTTHUMG00000131713 +81616 ACSBG2 MIM:614363|HGNC:HGNC:24174|Ensembl:ENSG00000130377|Vega:OTTHUMG00000180754 +81617 CAB39L MIM:612175|HGNC:HGNC:20290|Ensembl:ENSG00000102547|Vega:OTTHUMG00000016914 +81618 ITM2C MIM:609554|HGNC:HGNC:6175|Ensembl:ENSG00000135916|Vega:OTTHUMG00000133219 +81619 TSPAN14 HGNC:HGNC:23303|Ensembl:ENSG00000108219|Vega:OTTHUMG00000018615 +81620 CDT1 MIM:605525|HGNC:HGNC:24576|Ensembl:ENSG00000167513|Vega:OTTHUMG00000173467 +81621 KAZALD1 MIM:609208|HGNC:HGNC:25460|Ensembl:ENSG00000107821|Vega:OTTHUMG00000018918 +81622 UNC93B1 MIM:608204|HGNC:HGNC:13481|Ensembl:ENSG00000110057|Vega:OTTHUMG00000167472 +81623 DEFB126 HGNC:HGNC:15900|Ensembl:ENSG00000125788|Vega:OTTHUMG00000031616 +81624 DIAPH3 MIM:614567|HGNC:HGNC:15480|Ensembl:ENSG00000139734|Vega:OTTHUMG00000017004 +81626 SHCBP1L HGNC:HGNC:16788|Ensembl:ENSG00000157060|Vega:OTTHUMG00000035419 +81627 TRMT1L MIM:611673|HGNC:HGNC:16782|Ensembl:ENSG00000121486|Vega:OTTHUMG00000035389 +81628 TSC22D4 MIM:611914|HGNC:HGNC:21696|Ensembl:ENSG00000166925|Vega:OTTHUMG00000150233 +81629 TSSK3 MIM:607660|HGNC:HGNC:15473|Ensembl:ENSG00000162526|Vega:OTTHUMG00000007585 +81631 MAP1LC3B MIM:609604|HGNC:HGNC:13352|Ensembl:ENSG00000140941|Vega:OTTHUMG00000137654 +81669 CCNL2 MIM:613482|HGNC:HGNC:20570|Ensembl:ENSG00000221978|Vega:OTTHUMG00000002917 +81671 VMP1 MIM:611753|HGNC:HGNC:29559|Ensembl:ENSG00000062716|Vega:OTTHUMG00000179882 +81688 C6orf62 HGNC:HGNC:20998|Ensembl:ENSG00000112308|Vega:OTTHUMG00000014361 +81689 ISCA1 MIM:611006|HGNC:HGNC:28660|Ensembl:ENSG00000135070|Vega:OTTHUMG00000020135 +81691 REXO5 HGNC:HGNC:24661|Ensembl:ENSG00000005189|Vega:OTTHUMG00000131556 +81693 AMN MIM:605799|HGNC:HGNC:14604|Ensembl:ENSG00000166126|Vega:OTTHUMG00000171897 +81694 OR2W2P HGNC:HGNC:13970 +81695 OR2B7P HGNC:HGNC:13967 +81696 OR5V1 HGNC:HGNC:13972|Ensembl:ENSG00000243729|Vega:OTTHUMG00000031199 +81697 OR2B2 HGNC:HGNC:13966|Ensembl:ENSG00000168131|Vega:OTTHUMG00000014495 +81698 LINC00597 HGNC:HGNC:1193 +81704 DOCK8 MIM:611432|HGNC:HGNC:19191|Ensembl:ENSG00000107099|Vega:OTTHUMG00000078789 +81706 PPP1R14C MIM:613242|HGNC:HGNC:14952|Ensembl:ENSG00000198729|Vega:OTTHUMG00000015818 +81786 TRIM7 MIM:609315|HGNC:HGNC:16278|Ensembl:ENSG00000146054|Vega:OTTHUMG00000130963 +81788 NUAK2 MIM:608131|HGNC:HGNC:29558|Ensembl:ENSG00000163545|Vega:OTTHUMG00000037196 +81789 TIGD6 HGNC:HGNC:18332|Ensembl:ENSG00000164296|Vega:OTTHUMG00000130045 +81790 RNF170 MIM:614649|HGNC:HGNC:25358|Ensembl:ENSG00000120925|Vega:OTTHUMG00000165277 +81792 ADAMTS12 MIM:606184|HGNC:HGNC:14605|Ensembl:ENSG00000151388|Vega:OTTHUMG00000162088 +81793 TLR10 MIM:606270|HGNC:HGNC:15634|Ensembl:ENSG00000174123|Vega:OTTHUMG00000128578 +81794 ADAMTS10 MIM:608990|HGNC:HGNC:13201|Ensembl:ENSG00000142303|Vega:OTTHUMG00000182216 +81796 SLCO5A1 MIM:613543|HGNC:HGNC:19046|Ensembl:ENSG00000137571|Vega:OTTHUMG00000165121 +81797 OR12D3 HGNC:HGNC:13963|Ensembl:ENSG00000112462|Vega:OTTHUMG00000031051 +81831 NETO2 MIM:607974|HGNC:HGNC:14644|Ensembl:ENSG00000171208|Vega:OTTHUMG00000133101 +81832 NETO1 MIM:607973|HGNC:HGNC:13823|Ensembl:ENSG00000166342|Vega:OTTHUMG00000132834 +81833 SPACA1 MIM:612739|HGNC:HGNC:14967|Ensembl:ENSG00000118434|Vega:OTTHUMG00000015183 +81839 VANGL1 MIM:610132|HGNC:HGNC:15512|Ensembl:ENSG00000173218|Vega:OTTHUMG00000011971 +81844 TRIM56 MIM:616996|HGNC:HGNC:19028|Ensembl:ENSG00000169871|Vega:OTTHUMG00000157032 +81846 SBF2 MIM:607697|HGNC:HGNC:2135|Ensembl:ENSG00000133812|Vega:OTTHUMG00000165890 +81847 RNF146 MIM:612137|HGNC:HGNC:21336|Ensembl:ENSG00000118518|Vega:OTTHUMG00000015522 +81848 SPRY4 MIM:607984|HGNC:HGNC:15533|Ensembl:ENSG00000187678|Vega:OTTHUMG00000129663 +81849 ST6GALNAC5 MIM:610134|HGNC:HGNC:19342|Ensembl:ENSG00000117069|Vega:OTTHUMG00000009687 +81850 KRTAP1-3 MIM:608820|HGNC:HGNC:16771|Ensembl:ENSG00000221880|Vega:OTTHUMG00000133583 +81851 KRTAP1-1 MIM:608819|HGNC:HGNC:16772|Ensembl:ENSG00000188581|Vega:OTTHUMG00000133592 +81853 TMEM14B HGNC:HGNC:21384|Ensembl:ENSG00000137210|Vega:OTTHUMG00000014246 +81854 ZNF205-AS1 HGNC:HGNC:28586 +81855 SFXN3 MIM:615571|HGNC:HGNC:16087|Ensembl:ENSG00000107819|Vega:OTTHUMG00000018921 +81856 ZNF611 HGNC:HGNC:28766|Ensembl:ENSG00000213020|Vega:OTTHUMG00000154908 +81857 MED25 MIM:610197|HGNC:HGNC:28845|Ensembl:ENSG00000104973|Vega:OTTHUMG00000183161 +81858 SHARPIN MIM:611885|HGNC:HGNC:25321|Ensembl:ENSG00000179526|Vega:OTTHUMG00000165243 +81861 LPRS MIM:609888 +81863 CTPL1 MIM:605749|HGNC:HGNC:30997 +81864 EVR3 MIM:605750|HGNC:HGNC:32785 +81865 BFIC2 MIM:605751 +81866 NDIC MIM:605779 +81870 KRTAP9-9 HGNC:HGNC:16773|Ensembl:ENSG00000198083|Vega:OTTHUMG00000133602 +81871 KRTAP4-6 HGNC:HGNC:18909|Ensembl:ENSG00000198090|Vega:OTTHUMG00000133634 +81872 KRTAP2-1 HGNC:HGNC:16775|Ensembl:ENSG00000212725|Vega:OTTHUMG00000171405 +81873 ARPC5L HGNC:HGNC:23366|Ensembl:ENSG00000136950|Vega:OTTHUMG00000020660 +81875 ISG20L2 MIM:611930|HGNC:HGNC:25745|Ensembl:ENSG00000143319|Vega:OTTHUMG00000041301 +81876 RAB1B MIM:612565|HGNC:HGNC:18370|Ensembl:ENSG00000174903|Vega:OTTHUMG00000166916 +81887 LAS1L MIM:300964|HGNC:HGNC:25726|Ensembl:ENSG00000001497|Vega:OTTHUMG00000021720 +81888 HYI HGNC:HGNC:26948|Ensembl:ENSG00000178922|Vega:OTTHUMG00000007502 +81889 FAHD1 MIM:616320|HGNC:HGNC:14169|Ensembl:ENSG00000180185|Vega:OTTHUMG00000128663 +81890 QTRT1 MIM:609615|HGNC:HGNC:23797|Ensembl:ENSG00000213339|Vega:OTTHUMG00000180588 +81892 SLIRP MIM:610211|HGNC:HGNC:20495|Ensembl:ENSG00000119705|Vega:OTTHUMG00000171526 +81893 SLC7A5P1 HGNC:HGNC:29458 +81894 SLC25A28 MIM:609767|HGNC:HGNC:23472|Ensembl:ENSG00000155287|Vega:OTTHUMG00000018886 +81926 ABHD17A HGNC:HGNC:28756|Ensembl:ENSG00000129968|Vega:OTTHUMG00000171872 +81928 CABLES2 HGNC:HGNC:16143|Ensembl:ENSG00000149679|Vega:OTTHUMG00000032912 +81929 SEH1L MIM:609263|HGNC:HGNC:30379|Ensembl:ENSG00000085415|Vega:OTTHUMG00000181909 +81930 KIF18A MIM:611271|HGNC:HGNC:29441|Ensembl:ENSG00000121621|Vega:OTTHUMG00000166195 +81931 ZNF93 MIM:603975|HGNC:HGNC:13169|Ensembl:ENSG00000184635|Vega:OTTHUMG00000182371 +81932 HDHD3 HGNC:HGNC:28171|Ensembl:ENSG00000119431|Vega:OTTHUMG00000020524 +81993 COX17P1 HGNC:HGNC:24341 +82500 PKP2P1 HGNC:HGNC:13413 +83259 PCDH11Y MIM:400022|HGNC:HGNC:15813|Ensembl:ENSG00000099715|Vega:OTTHUMG00000035105 +83394 PITPNM3 MIM:608921|HGNC:HGNC:21043|Ensembl:ENSG00000091622|Vega:OTTHUMG00000102039 +83401 ELOVL3 MIM:611815|HGNC:HGNC:18047|Ensembl:ENSG00000119915|Vega:OTTHUMG00000018951 +83416 FCRL5 MIM:605877|HGNC:HGNC:18508|Ensembl:ENSG00000143297|Vega:OTTHUMG00000017481 +83417 FCRL4 MIM:605876|HGNC:HGNC:18507|Ensembl:ENSG00000163518|Vega:OTTHUMG00000035488 +83439 TCF7L1 MIM:604652|HGNC:HGNC:11640|Ensembl:ENSG00000152284|Vega:OTTHUMG00000130026 +83440 ADPGK MIM:611861|HGNC:HGNC:25250|Ensembl:ENSG00000159322|Vega:OTTHUMG00000172777 +83442 SH3BGRL3 MIM:615679|HGNC:HGNC:15568|Ensembl:ENSG00000142669|Vega:OTTHUMG00000003381 +83443 SF3B5 HGNC:HGNC:21083|Ensembl:ENSG00000169976|Vega:OTTHUMG00000015737 +83444 INO80B MIM:616456|HGNC:HGNC:13324|Ensembl:ENSG00000115274|Vega:OTTHUMG00000129959 +83445 GSG1 HGNC:HGNC:19716|Ensembl:ENSG00000111305|Vega:OTTHUMG00000150148 +83446 CCDC70 HGNC:HGNC:25303|Ensembl:ENSG00000123171|Vega:OTTHUMG00000016950 +83447 SLC25A31 MIM:610796|HGNC:HGNC:25319|Ensembl:ENSG00000151475|Vega:OTTHUMG00000133300 +83448 PUS7L HGNC:HGNC:25276|Ensembl:ENSG00000129317|Vega:OTTHUMG00000169423 +83449 PMFBP1 HGNC:HGNC:17728|Ensembl:ENSG00000118557|Vega:OTTHUMG00000167827 +83450 DRC3 HGNC:HGNC:25384|Ensembl:ENSG00000171962|Vega:OTTHUMG00000059355 +83451 ABHD11 HGNC:HGNC:16407|Ensembl:ENSG00000106077|Vega:OTTHUMG00000130029 +83452 RAB33B MIM:605950|HGNC:HGNC:16075|Ensembl:ENSG00000172007|Vega:OTTHUMG00000133384 +83460 EMC6 HGNC:HGNC:28430|Ensembl:ENSG00000127774|Vega:OTTHUMG00000180187 +83461 CDCA3 MIM:607749|HGNC:HGNC:14624|Ensembl:ENSG00000111665|Vega:OTTHUMG00000169014 +83463 MXD3 MIM:609450|HGNC:HGNC:14008|Ensembl:ENSG00000213347|Vega:OTTHUMG00000130854 +83464 APH1B MIM:607630|HGNC:HGNC:24080|Ensembl:ENSG00000138613|Vega:OTTHUMG00000132863 +83468 GLT8D2 HGNC:HGNC:24890|Ensembl:ENSG00000120820|Vega:OTTHUMG00000170120 +83473 KATNAL2 MIM:614697|HGNC:HGNC:25387|Ensembl:ENSG00000167216|Vega:OTTHUMG00000179408 +83475 DOHH MIM:611262|HGNC:HGNC:28662|Ensembl:ENSG00000129932|Vega:OTTHUMG00000180762 +83478 ARHGAP24 MIM:610586|HGNC:HGNC:25361|Ensembl:ENSG00000138639|Vega:OTTHUMG00000130427 +83479 DDX59 MIM:615464|HGNC:HGNC:25360|Ensembl:ENSG00000118197|Vega:OTTHUMG00000035725 +83480 PUS3 MIM:616283|HGNC:HGNC:25461|Ensembl:ENSG00000110060|Vega:OTTHUMG00000165870 +83481 EPPK1 MIM:607553|HGNC:HGNC:15577|Ensembl:ENSG00000261150|Vega:OTTHUMG00000165206 +83482 SCRT1 MIM:605858|HGNC:HGNC:15950|Ensembl:ENSG00000261678|Vega:OTTHUMG00000165229 +83483 PLVAP MIM:607647|HGNC:HGNC:13635|Ensembl:ENSG00000130300|Vega:OTTHUMG00000182784 +83528 CYP51A1P1 HGNC:HGNC:20245 +83530 CYP51A1P2 HGNC:HGNC:20251 +83538 TTC25 MIM:617095|HGNC:HGNC:25280|Ensembl:ENSG00000204815|Vega:OTTHUMG00000175837 +83539 CHST9 MIM:610191|HGNC:HGNC:19898|Ensembl:ENSG00000154080|Vega:OTTHUMG00000179469 +83540 NUF2 MIM:611772|HGNC:HGNC:14621|Ensembl:ENSG00000143228|Vega:OTTHUMG00000034275 +83541 FAM110A MIM:611393|HGNC:HGNC:16188|Ensembl:ENSG00000125898|Vega:OTTHUMG00000031649 +83543 AIF1L HGNC:HGNC:28904|Ensembl:ENSG00000126878|Vega:OTTHUMG00000020817 +83544 DNAL1 MIM:610062|HGNC:HGNC:23247|Ensembl:ENSG00000119661|Vega:OTTHUMG00000171642 +83546 RTBDN MIM:609553|HGNC:HGNC:30310|Ensembl:ENSG00000132026|Vega:OTTHUMG00000180482 +83547 RILP MIM:607848|HGNC:HGNC:30266|Ensembl:ENSG00000167705|Vega:OTTHUMG00000090554 +83548 COG3 MIM:606975|HGNC:HGNC:18619|Ensembl:ENSG00000136152|Vega:OTTHUMG00000016855 +83549 UCK1 MIM:609328|HGNC:HGNC:14859|Ensembl:ENSG00000130717|Vega:OTTHUMG00000020823 +83550 GPR101 MIM:300393|HGNC:HGNC:14963|Ensembl:ENSG00000165370|Vega:OTTHUMG00000022521 +83551 TAAR8 MIM:606927|HGNC:HGNC:14964|Ensembl:ENSG00000146385|Vega:OTTHUMG00000015586 +83552 MFRP MIM:606227|HGNC:HGNC:18121|Ensembl:ENSG00000235718|Vega:OTTHUMG00000166199 +83590 TMUB1 MIM:614792|HGNC:HGNC:21709|Ensembl:ENSG00000164897|Vega:OTTHUMG00000158621 +83591 THAP2 MIM:612531|HGNC:HGNC:20854|Ensembl:ENSG00000173451|Vega:OTTHUMG00000169556 +83592 AKR1E2 MIM:617451|HGNC:HGNC:23437|Ensembl:ENSG00000165568|Vega:OTTHUMG00000017577 +83593 RASSF5 MIM:607020|HGNC:HGNC:17609|Ensembl:ENSG00000266094|Vega:OTTHUMG00000184616 +83594 NUDT12 MIM:609232|HGNC:HGNC:18826|Ensembl:ENSG00000112874|Vega:OTTHUMG00000128739 +83595 SOX7 MIM:612202|HGNC:HGNC:18196|Ensembl:ENSG00000171056|Vega:OTTHUMG00000090585 +83596 BCL2L12 MIM:610837|HGNC:HGNC:13787|Ensembl:ENSG00000126453|Vega:OTTHUMG00000183239 +83597 RTP3 MIM:607181|HGNC:HGNC:15572|Ensembl:ENSG00000163825|Vega:OTTHUMG00000133483 +83598 LRRC2-AS1 HGNC:HGNC:15571|Ensembl:ENSG00000268324 +83604 TMEM47 MIM:300698|HGNC:HGNC:18515|Ensembl:ENSG00000147027|Vega:OTTHUMG00000021343 +83605 CCM2 MIM:607929|HGNC:HGNC:21708|Ensembl:ENSG00000136280|Vega:OTTHUMG00000129246 +83606 GUCD1 HGNC:HGNC:14237|Ensembl:ENSG00000138867|Vega:OTTHUMG00000150728 +83607 AMMECR1L HGNC:HGNC:28658|Ensembl:ENSG00000144233|Vega:OTTHUMG00000131535 +83608 C18orf21 HGNC:HGNC:28802|Ensembl:ENSG00000141428|Vega:OTTHUMG00000128531 +83636 C19orf12 MIM:614297|HGNC:HGNC:25443|Ensembl:ENSG00000131943|Vega:OTTHUMG00000149838 +83637 ZMIZ2 MIM:611196|HGNC:HGNC:22229|Ensembl:ENSG00000122515|Vega:OTTHUMG00000155817 +83638 C11orf68 HGNC:HGNC:28801|Ensembl:ENSG00000175573|Vega:OTTHUMG00000157153 +83639 TEX101 MIM:612665|HGNC:HGNC:30722|Ensembl:ENSG00000131126|Vega:OTTHUMG00000182695 +83640 FAM103A1 MIM:614547|HGNC:HGNC:31022|Ensembl:ENSG00000169612|Vega:OTTHUMG00000147357 +83641 FAM107B HGNC:HGNC:23726|Ensembl:ENSG00000065809|Vega:OTTHUMG00000017709 +83642 SELENOO MIM:607917|HGNC:HGNC:30395|Ensembl:ENSG00000073169|Vega:OTTHUMG00000044645 +83643 CCDC3 HGNC:HGNC:23813|Ensembl:ENSG00000151468|Vega:OTTHUMG00000017689 +83647 LINC00529 HGNC:HGNC:15544 +83648 FAM167A MIM:610085|HGNC:HGNC:15549|Ensembl:ENSG00000154319|Vega:OTTHUMG00000129361 +83650 SLC35G5 MIM:615199|HGNC:HGNC:15546|Ensembl:ENSG00000177710|Vega:OTTHUMG00000090653 +83655 LINC00208 HGNC:HGNC:15535|Ensembl:ENSG00000170983 +83656 FAM167A-AS1 HGNC:HGNC:15548|Ensembl:ENSG00000184608 +83657 DYNLRB2 MIM:607168|HGNC:HGNC:15467|Ensembl:ENSG00000168589|Vega:OTTHUMG00000137622 +83658 DYNLRB1 MIM:607167|HGNC:HGNC:15468|Ensembl:ENSG00000125971|Vega:OTTHUMG00000032302 +83659 TEKT1 MIM:609002|HGNC:HGNC:15534|Ensembl:ENSG00000167858|Vega:OTTHUMG00000102063 +83660 TLN2 MIM:607349|HGNC:HGNC:15447|Ensembl:ENSG00000171914|Vega:OTTHUMG00000133679 +83661 MS4A8 MIM:606549|HGNC:HGNC:13380|Ensembl:ENSG00000166959|Vega:OTTHUMG00000167686 +83666 PARP9 MIM:612065|HGNC:HGNC:24118|Ensembl:ENSG00000138496|Vega:OTTHUMG00000159522 +83667 SESN2 MIM:607767|HGNC:HGNC:20746|Ensembl:ENSG00000130766|Vega:OTTHUMG00000003532 +83690 CRISPLD1 HGNC:HGNC:18206|Ensembl:ENSG00000121005|Vega:OTTHUMG00000164529 +83692 CD99L2 MIM:300846|HGNC:HGNC:18237|Ensembl:ENSG00000102181|Vega:OTTHUMG00000024247 +83693 HSDL1 HGNC:HGNC:16475|Ensembl:ENSG00000103160|Vega:OTTHUMG00000137635 +83694 RPS6KL1 HGNC:HGNC:20222|Ensembl:ENSG00000198208|Vega:OTTHUMG00000171484 +83695 RHNO1 MIM:614085|HGNC:HGNC:28206|Ensembl:ENSG00000171792|Vega:OTTHUMG00000158557 +83696 TRAPPC9 MIM:611966|HGNC:HGNC:30832|Ensembl:ENSG00000167632|Vega:OTTHUMG00000164187 +83697 SLC4A9 MIM:610207|HGNC:HGNC:11035|Ensembl:ENSG00000113073|Vega:OTTHUMG00000163352 +83698 CALN1 MIM:607176|HGNC:HGNC:13248|Ensembl:ENSG00000183166|Vega:OTTHUMG00000023787 +83699 SH3BGRL2 MIM:615678|HGNC:HGNC:15567|Ensembl:ENSG00000198478|Vega:OTTHUMG00000015081 +83700 JAM3 MIM:606871|HGNC:HGNC:15532|Ensembl:ENSG00000166086|Vega:OTTHUMG00000167130 +83706 FERMT3 MIM:607901|HGNC:HGNC:23151|Ensembl:ENSG00000149781|Vega:OTTHUMG00000167790 +83707 TRPT1 MIM:610470|HGNC:HGNC:20316|Ensembl:ENSG00000149743|Vega:OTTHUMG00000167844 +83714 NRIP2 HGNC:HGNC:23078|Ensembl:ENSG00000053702|Vega:OTTHUMG00000130616 +83715 ESPN MIM:606351|HGNC:HGNC:13281|Ensembl:ENSG00000187017|Vega:OTTHUMG00000000753 +83716 CRISPLD2 MIM:612434|HGNC:HGNC:25248|Ensembl:ENSG00000103196|Vega:OTTHUMG00000137644 +83719 YPEL3 MIM:609724|HGNC:HGNC:18327|Ensembl:ENSG00000090238|Vega:OTTHUMG00000176853 +83723 FAM57B MIM:615175|HGNC:HGNC:25295|Ensembl:ENSG00000149926|Vega:OTTHUMG00000132105 +83729 INHBE MIM:612031|HGNC:HGNC:24029|Ensembl:ENSG00000139269|Vega:OTTHUMG00000169995 +83732 RIOK1 HGNC:HGNC:18656|Ensembl:ENSG00000124784|Vega:OTTHUMG00000014207 +83733 SLC25A18 MIM:609303|HGNC:HGNC:10988|Ensembl:ENSG00000182902|Vega:OTTHUMG00000150089 +83734 ATG10 MIM:610800|HGNC:HGNC:20315|Ensembl:ENSG00000152348|Vega:OTTHUMG00000119041 +83737 ITCH MIM:606409|HGNC:HGNC:13890|Ensembl:ENSG00000078747|Vega:OTTHUMG00000032300 +83740 H2AFB3 MIM:300445|HGNC:HGNC:14455|Ensembl:ENSG00000277745|Vega:OTTHUMG00000022670 +83741 TFAP2D MIM:610161|HGNC:HGNC:15581|Ensembl:ENSG00000008197|Vega:OTTHUMG00000014832 +83742 MARVELD1 MIM:616970|HGNC:HGNC:28674|Ensembl:ENSG00000155254|Vega:OTTHUMG00000018865 +83743 GRWD1 MIM:610597|HGNC:HGNC:21270|Ensembl:ENSG00000105447|Vega:OTTHUMG00000183305 +83744 ZNF484 HGNC:HGNC:23385|Ensembl:ENSG00000127081|Vega:OTTHUMG00000020236 +83746 L3MBTL2 MIM:611865|HGNC:HGNC:18594|Ensembl:ENSG00000100395|Vega:OTTHUMG00000150942 +83752 LONP2 HGNC:HGNC:20598|Ensembl:ENSG00000102910|Vega:OTTHUMG00000133144 +83755 KRTAP4-12 HGNC:HGNC:16776|Ensembl:ENSG00000213416|Vega:OTTHUMG00000133632 +83756 TAS1R3 MIM:605865|HGNC:HGNC:15661|Ensembl:ENSG00000169962|Vega:OTTHUMG00000003071 +83757 CYP2G2P HGNC:HGNC:15653 +83758 RBP5 MIM:611866|HGNC:HGNC:15847|Ensembl:ENSG00000139194|Vega:OTTHUMG00000168165 +83759 RBM4B HGNC:HGNC:28842|Ensembl:ENSG00000173914|Vega:OTTHUMG00000167243 +83786 FRMD8 HGNC:HGNC:25462|Ensembl:ENSG00000126391|Vega:OTTHUMG00000166275 +83787 ARMC10 MIM:611864|HGNC:HGNC:21706|Ensembl:ENSG00000170632|Vega:OTTHUMG00000157201 +83795 KCNK16 MIM:607369|HGNC:HGNC:14464|Ensembl:ENSG00000095981|Vega:OTTHUMG00000014645 +83844 USP26 MIM:300309|HGNC:HGNC:13485|Ensembl:ENSG00000134588|Vega:OTTHUMG00000022429 +83849 SYT15 MIM:608081|HGNC:HGNC:17167|Ensembl:ENSG00000204176|Vega:OTTHUMG00000018103 +83850 ESYT3 MIM:616692|HGNC:HGNC:24295|Ensembl:ENSG00000158220|Vega:OTTHUMG00000147354 +83851 SYT16 MIM:610950|HGNC:HGNC:23142|Ensembl:ENSG00000139973|Vega:OTTHUMG00000171106 +83852 SETDB2 MIM:607865|HGNC:HGNC:20263|Ensembl:ENSG00000136169|Vega:OTTHUMG00000016918 +83853 ROPN1L MIM:611756|HGNC:HGNC:24060|Ensembl:ENSG00000145491|Vega:OTTHUMG00000090507 +83854 ANGPTL6 MIM:609336|HGNC:HGNC:23140|Ensembl:ENSG00000130812|Vega:OTTHUMG00000180395 +83855 KLF16 MIM:606139|HGNC:HGNC:16857|Ensembl:ENSG00000129911|Vega:OTTHUMG00000179994 +83856 FSD1L MIM:609829|HGNC:HGNC:13753|Ensembl:ENSG00000106701|Vega:OTTHUMG00000020426 +83857 TMTC1 MIM:615855|HGNC:HGNC:24099|Ensembl:ENSG00000133687|Vega:OTTHUMG00000169324 +83858 ATAD3B MIM:612317|HGNC:HGNC:24007|Ensembl:ENSG00000160072|Vega:OTTHUMG00000000577 +83860 TAF3 MIM:606576|HGNC:HGNC:17303|Ensembl:ENSG00000165632|Vega:OTTHUMG00000017643 +83861 RSPH3 MIM:615876|HGNC:HGNC:21054|Ensembl:ENSG00000130363 +83862 TMEM120A MIM:616550|HGNC:HGNC:21697|Ensembl:ENSG00000189077|Vega:OTTHUMG00000156620 +83863 TTTY5 MIM:400038|HGNC:HGNC:16482|Ensembl:ENSG00000215560 +83864 TTTY9A HGNC:HGNC:18490|Ensembl:ENSG00000242153 +83866 TTTY11 HGNC:HGNC:18492|Ensembl:ENSG00000180910 +83867 TTTY12 HGNC:HGNC:18493|Ensembl:ENSG00000237048 +83868 TTTY13 HGNC:HGNC:18494|Ensembl:ENSG00000184991 +83869 TTTY14 HGNC:HGNC:18495 +83871 RAB34 MIM:610917|HGNC:HGNC:16519|Ensembl:ENSG00000109113|Vega:OTTHUMG00000132680 +83872 HMCN1 MIM:608548|HGNC:HGNC:19194|Ensembl:ENSG00000143341|Vega:OTTHUMG00000059337 +83873 GPR61 MIM:606916|HGNC:HGNC:13300|Ensembl:ENSG00000156097|Vega:OTTHUMG00000011633 +83874 TBC1D10A MIM:610020|HGNC:HGNC:23609|Ensembl:ENSG00000099992|Vega:OTTHUMG00000150924 +83875 BCO2 MIM:611740|HGNC:HGNC:18503|Ensembl:ENSG00000197580|Vega:OTTHUMG00000167155 +83876 MRO MIM:608080|HGNC:HGNC:24121|Ensembl:ENSG00000134042|Vega:OTTHUMG00000132692 +83877 TM2D2 MIM:610081|HGNC:HGNC:24127|Ensembl:ENSG00000169490|Vega:OTTHUMG00000164098 +83878 USHBP1 MIM:611810|HGNC:HGNC:24058|Ensembl:ENSG00000130307|Vega:OTTHUMG00000182730 +83879 CDCA7 MIM:609937|HGNC:HGNC:14628|Ensembl:ENSG00000144354|Vega:OTTHUMG00000132296 +83880 EIF3FP2 HGNC:HGNC:28863 +83881 MIXL1 MIM:609852|HGNC:HGNC:13363|Ensembl:ENSG00000185155|Vega:OTTHUMG00000037558 +83882 TSPAN10 HGNC:HGNC:29942|Ensembl:ENSG00000182612|Vega:OTTHUMG00000178037 +83884 SLC25A2 MIM:608157|HGNC:HGNC:22921|Ensembl:ENSG00000120329|Vega:OTTHUMG00000129604 +83886 PRSS27 MIM:608018|HGNC:HGNC:15475|Ensembl:ENSG00000172382|Vega:OTTHUMG00000128929 +83887 TTLL2 HGNC:HGNC:21211|Ensembl:ENSG00000120440|Vega:OTTHUMG00000016023 +83888 FGFBP2 MIM:607713|HGNC:HGNC:29451|Ensembl:ENSG00000137441|Vega:OTTHUMG00000128513 +83889 WDR87 HGNC:HGNC:29934|Ensembl:ENSG00000171804|Vega:OTTHUMG00000048187 +83890 SPATA9 MIM:608039|HGNC:HGNC:22988|Ensembl:ENSG00000145757|Vega:OTTHUMG00000121169 +83891 SNX25 HGNC:HGNC:21883|Ensembl:ENSG00000109762|Vega:OTTHUMG00000160475 +83892 KCTD10 MIM:613421|HGNC:HGNC:23236|Ensembl:ENSG00000110906|Vega:OTTHUMG00000169253 +83893 SPATA16 MIM:609856|HGNC:HGNC:29935|Ensembl:ENSG00000144962|Vega:OTTHUMG00000156865 +83894 TTC29 HGNC:HGNC:29936|Ensembl:ENSG00000137473|Vega:OTTHUMG00000162047 +83895 KRTAP1-5 MIM:608822|HGNC:HGNC:16777|Ensembl:ENSG00000221852|Vega:OTTHUMG00000133587 +83896 KRTAP3-1 HGNC:HGNC:16778|Ensembl:ENSG00000212901|Vega:OTTHUMG00000133595 +83897 KRTAP3-2 HGNC:HGNC:16779|Ensembl:ENSG00000212900|Vega:OTTHUMG00000133581 +83899 KRTAP9-2 HGNC:HGNC:16926|Ensembl:ENSG00000239886|Vega:OTTHUMG00000133609 +83900 KRTAP9-3 HGNC:HGNC:16927|Ensembl:ENSG00000204873|Vega:OTTHUMG00000133427 +83901 KRTAP9-8 HGNC:HGNC:17231|Ensembl:ENSG00000187272|Vega:OTTHUMG00000133604 +83902 KRTAP17-1 HGNC:HGNC:18917|Ensembl:ENSG00000186860|Vega:OTTHUMG00000133433 +83903 HASPIN MIM:609240|HGNC:HGNC:19682|Ensembl:ENSG00000177602|Vega:OTTHUMG00000090703 +83930 STARD3NL MIM:611759|HGNC:HGNC:19169|Ensembl:ENSG00000010270|Vega:OTTHUMG00000023659 +83931 STK40 MIM:609437|HGNC:HGNC:21373|Ensembl:ENSG00000196182|Vega:OTTHUMG00000008238 +83932 SPRTN MIM:616086|HGNC:HGNC:25356|Ensembl:ENSG00000010072|Vega:OTTHUMG00000038022 +83933 HDAC10 MIM:608544|HGNC:HGNC:18128|Ensembl:ENSG00000100429|Vega:OTTHUMG00000044647 +83935 TMEM133 HGNC:HGNC:24033|Ensembl:ENSG00000170647|Vega:OTTHUMG00000167577 +83937 RASSF4 MIM:610559|HGNC:HGNC:20793|Ensembl:ENSG00000107551|Vega:OTTHUMG00000018060 +83938 LRMDA MIM:614537|HGNC:HGNC:23405|Ensembl:ENSG00000148655|Vega:OTTHUMG00000018532 +83939 EIF2A MIM:609234|HGNC:HGNC:3254|Ensembl:ENSG00000144895|Vega:OTTHUMG00000159775 +83940 TATDN1 HGNC:HGNC:24220|Ensembl:ENSG00000147687|Vega:OTTHUMG00000165068 +83941 TM2D1 MIM:610080|HGNC:HGNC:24142|Ensembl:ENSG00000162604|Vega:OTTHUMG00000008466 +83942 TSSK1B MIM:610709|HGNC:HGNC:14968|Ensembl:ENSG00000212122|Vega:OTTHUMG00000128835 +83943 IMMP2L MIM:605977|HGNC:HGNC:14598|Ensembl:ENSG00000184903|Vega:OTTHUMG00000155023 +83953 FCAMR MIM:605484|HGNC:HGNC:24692|Ensembl:ENSG00000162897|Vega:OTTHUMG00000036579 +83955 NACAP1 HGNC:HGNC:24688|Ensembl:ENSG00000228224 +83956 RACGAP1P HGNC:HGNC:24689 +83957 FRMD8P1 HGNC:HGNC:24690|Ensembl:ENSG00000227942 +83959 SLC4A11 MIM:610206|HGNC:HGNC:16438|Ensembl:ENSG00000088836|Vega:OTTHUMG00000031740 +83982 IFI27L2 MIM:611319|HGNC:HGNC:19753|Ensembl:ENSG00000119632|Vega:OTTHUMG00000171313 +83983 TSSK6 MIM:610712|HGNC:HGNC:30410|Ensembl:ENSG00000178093|Vega:OTTHUMG00000182146 +83985 SPNS1 MIM:612583|HGNC:HGNC:30621|Ensembl:ENSG00000169682|Vega:OTTHUMG00000131762 +83986 FAM234A HGNC:HGNC:14163|Ensembl:ENSG00000167930|Ensembl:ENSG00000269881|Vega:OTTHUMG00000060728|Vega:OTTHUMG00000183024 +83987 CCDC8 MIM:614145|HGNC:HGNC:25367|Ensembl:ENSG00000169515|Vega:OTTHUMG00000162348 +83988 NCALD MIM:606722|HGNC:HGNC:7655|Ensembl:ENSG00000104490|Vega:OTTHUMG00000164876 +83989 FAM172A HGNC:HGNC:25365|Ensembl:ENSG00000113391|Vega:OTTHUMG00000131329 +83990 BRIP1 MIM:605882|HGNC:HGNC:20473|Ensembl:ENSG00000136492|Vega:OTTHUMG00000179233 +83992 CTTNBP2 MIM:609772|HGNC:HGNC:15679|Ensembl:ENSG00000077063|Vega:OTTHUMG00000022880 +83998 REG4 MIM:609846|HGNC:HGNC:22977|Ensembl:ENSG00000134193|Vega:OTTHUMG00000012175 +83999 KREMEN1 MIM:609898|HGNC:HGNC:17550|Ensembl:ENSG00000183762|Vega:OTTHUMG00000030987 +84000 TMPRSS13 MIM:610050|HGNC:HGNC:29808|Ensembl:ENSG00000137747|Vega:OTTHUMG00000166992 +84002 B3GNT5 MIM:615333|HGNC:HGNC:15684|Ensembl:ENSG00000176597|Vega:OTTHUMG00000158436 +84033 OBSCN MIM:608616|HGNC:HGNC:15719|Ensembl:ENSG00000154358|Vega:OTTHUMG00000039772 +84034 EMILIN2 MIM:608928|HGNC:HGNC:19881|Ensembl:ENSG00000132205|Vega:OTTHUMG00000128525 +84054 PCDHB19P HGNC:HGNC:14549 +84055 PCDHGB9P HGNC:HGNC:15688 +84056 KATNAL1 MIM:614764|HGNC:HGNC:28361|Ensembl:ENSG00000102781|Vega:OTTHUMG00000016665 +84057 MND1 MIM:611422|HGNC:HGNC:24839|Ensembl:ENSG00000121211|Vega:OTTHUMG00000161523 +84058 WDR54 HGNC:HGNC:25770|Ensembl:ENSG00000005448|Vega:OTTHUMG00000129951 +84059 ADGRV1 MIM:602851|HGNC:HGNC:17416|Ensembl:ENSG00000164199|Vega:OTTHUMG00000162668 +84060 RBM48 HGNC:HGNC:21785|Ensembl:ENSG00000127993|Vega:OTTHUMG00000159535 +84061 MAGT1 MIM:300715|HGNC:HGNC:28880|Ensembl:ENSG00000102158|Vega:OTTHUMG00000021882 +84062 DTNBP1 MIM:607145|HGNC:HGNC:17328|Ensembl:ENSG00000047579|Vega:OTTHUMG00000014295 +84063 KIRREL2 MIM:607762|HGNC:HGNC:18816|Ensembl:ENSG00000126259|Vega:OTTHUMG00000180691 +84064 HDHD2 HGNC:HGNC:25364|Ensembl:ENSG00000167220|Vega:OTTHUMG00000179411 +84065 TMEM222 HGNC:HGNC:25363|Ensembl:ENSG00000186501|Vega:OTTHUMG00000004410 +84066 TEX35 HGNC:HGNC:25366|Ensembl:ENSG00000240021|Vega:OTTHUMG00000035023 +84067 FAM160A2 HGNC:HGNC:25378|Ensembl:ENSG00000051009|Vega:OTTHUMG00000133379 +84068 SLC10A7 MIM:611459|HGNC:HGNC:23088|Ensembl:ENSG00000120519|Vega:OTTHUMG00000161437 +84069 PLEKHN1 HGNC:HGNC:25284|Ensembl:ENSG00000187583|Vega:OTTHUMG00000040756 +84070 FAM186B HGNC:HGNC:25296|Ensembl:ENSG00000135436|Vega:OTTHUMG00000167427 +84071 ARMC2 HGNC:HGNC:23045|Ensembl:ENSG00000118690|Vega:OTTHUMG00000015335 +84072 HORMAD1 MIM:609824|HGNC:HGNC:25245|Ensembl:ENSG00000143452|Vega:OTTHUMG00000035005 +84073 MYCBPAP MIM:609835|HGNC:HGNC:19677|Ensembl:ENSG00000136449|Vega:OTTHUMG00000157184 +84074 QRICH2 HGNC:HGNC:25326|Ensembl:ENSG00000129646|Vega:OTTHUMG00000167578 +84075 FSCB MIM:611779|HGNC:HGNC:20494|Ensembl:ENSG00000189139|Vega:OTTHUMG00000140262 +84076 TKTL2 HGNC:HGNC:25313|Ensembl:ENSG00000151005|Vega:OTTHUMG00000161527 +84077 C3orf20 HGNC:HGNC:25320|Ensembl:ENSG00000131379|Vega:OTTHUMG00000155545 +84078 KBTBD7 HGNC:HGNC:25266|Ensembl:ENSG00000120696|Vega:OTTHUMG00000016789 +84079 ANKRD27 HGNC:HGNC:25310|Ensembl:ENSG00000105186|Vega:OTTHUMG00000180225 +84080 ENKD1 HGNC:HGNC:25246|Ensembl:ENSG00000124074|Vega:OTTHUMG00000137550 +84081 NSRP1 MIM:616173|HGNC:HGNC:25305|Ensembl:ENSG00000126653|Vega:OTTHUMG00000132754 +84083 ZRANB3 MIM:615655|HGNC:HGNC:25249|Ensembl:ENSG00000121988|Vega:OTTHUMG00000150475 +84084 RAB6C MIM:612909|HGNC:HGNC:16525|Ensembl:ENSG00000222014|Vega:OTTHUMG00000153487 +84085 FBXO30 MIM:609101|HGNC:HGNC:15600|Ensembl:ENSG00000118496|Vega:OTTHUMG00000015749 +84086 IGLCOR22-2 HGNC:HGNC:15697|IMGT/GENE-DB:IGLC/OR22-2 +84087 IGLVIVOR22-2 HGNC:HGNC:15695|IMGT/GENE-DB:IGLV(IV)/OR22-2 +84088 IGLVIVOR22-1 HGNC:HGNC:15694|IMGT/GENE-DB:IGLV(IV)/OR22-1 +84089 IGLVVII-41-1 HGNC:HGNC:15691|IMGT/GENE-DB:IGLV(VII)-41-1 +84090 IGLVVI-25-1 HGNC:HGNC:15690|IMGT/GENE-DB:IGLV(VI)-25-1 +84091 IGLVVI-22-1 HGNC:HGNC:15689|IMGT/GENE-DB:IGLV(VI)-22-1 +84096 IGLCOR22-1 HGNC:HGNC:15696|IMGT/GENE-DB:IGLC/OR22-1 +84097 IGLVIV-66-1 HGNC:HGNC:15692|IMGT/GENE-DB:IGLV(IV)-66-1 +84099 ID2B HGNC:HGNC:30656 +84100 ARL6 MIM:608845|HGNC:HGNC:13210|Ensembl:ENSG00000113966|Vega:OTTHUMG00000159189 +84101 USP44 MIM:610993|HGNC:HGNC:20064|Ensembl:ENSG00000136014|Vega:OTTHUMG00000170281 +84102 SLC41A2 MIM:610802|HGNC:HGNC:31045|Ensembl:ENSG00000136052|Vega:OTTHUMG00000156965 +84103 C4orf17 HGNC:HGNC:25274|Ensembl:ENSG00000138813|Vega:OTTHUMG00000131027 +84105 PCBD2 MIM:609836|HGNC:HGNC:24474|Ensembl:ENSG00000132570|Vega:OTTHUMG00000163070 +84106 PRAM1 MIM:606466|HGNC:HGNC:30091|Ensembl:ENSG00000133246|Vega:OTTHUMG00000167924 +84107 ZIC4 MIM:608948|HGNC:HGNC:20393|Ensembl:ENSG00000174963|Vega:OTTHUMG00000037281 +84108 PCGF6 MIM:607816|HGNC:HGNC:21156|Ensembl:ENSG00000156374|Vega:OTTHUMG00000018982 +84109 QRFPR MIM:606925|HGNC:HGNC:15565|Ensembl:ENSG00000186867|Vega:OTTHUMG00000133036 +84124 ZNF394 HGNC:HGNC:18832|Ensembl:ENSG00000160908|Vega:OTTHUMG00000154660 +84125 LRRIQ1 HGNC:HGNC:25708|Ensembl:ENSG00000133640|Vega:OTTHUMG00000166185 +84126 ATRIP MIM:606605|HGNC:HGNC:33499|Ensembl:ENSG00000164053|Ensembl:ENSG00000282827|Vega:OTTHUMG00000133532 +84128 WDR75 HGNC:HGNC:25725|Ensembl:ENSG00000115368|Vega:OTTHUMG00000132660 +84129 ACAD11 MIM:614288|HGNC:HGNC:30211|Ensembl:ENSG00000240303|Vega:OTTHUMG00000159780 +84131 CEP78 MIM:617110|HGNC:HGNC:25740|Ensembl:ENSG00000148019|Vega:OTTHUMG00000020062 +84132 USP42 HGNC:HGNC:20068|Ensembl:ENSG00000106346|Vega:OTTHUMG00000151888 +84133 ZNRF3 MIM:612062|HGNC:HGNC:18126|Ensembl:ENSG00000183579|Vega:OTTHUMG00000151009 +84134 TOMM40L HGNC:HGNC:25756|Ensembl:ENSG00000158882|Vega:OTTHUMG00000034345 +84135 UTP15 MIM:616194|HGNC:HGNC:25758|Ensembl:ENSG00000164338|Vega:OTTHUMG00000162453 +84138 SLC7A6OS HGNC:HGNC:25807|Ensembl:ENSG00000103061|Vega:OTTHUMG00000137558 +84140 FAM161A MIM:613596|HGNC:HGNC:25808|Ensembl:ENSG00000170264|Vega:OTTHUMG00000152165 +84141 EVA1A HGNC:HGNC:25816|Ensembl:ENSG00000115363|Vega:OTTHUMG00000129991 +84142 ABRAXAS1 MIM:611143|HGNC:HGNC:25829|Ensembl:ENSG00000163322|Vega:OTTHUMG00000130429 +84144 SYDE2 HGNC:HGNC:25841|Ensembl:ENSG00000097096|Vega:OTTHUMG00000009956 +84146 ZNF644 MIM:614159|HGNC:HGNC:29222|Ensembl:ENSG00000122482|Vega:OTTHUMG00000010078 +84148 KAT8 MIM:609912|HGNC:HGNC:17933|Ensembl:ENSG00000103510|Vega:OTTHUMG00000132410 +84152 PPP1R1B MIM:604399|HGNC:HGNC:9287|Ensembl:ENSG00000131771|Vega:OTTHUMG00000133210 +84153 RNASEH2C MIM:610330|HGNC:HGNC:24116|Ensembl:ENSG00000172922|Vega:OTTHUMG00000166601 +84154 RPF2 HGNC:HGNC:20870|Ensembl:ENSG00000197498|Vega:OTTHUMG00000015368 +84159 ARID5B MIM:608538|HGNC:HGNC:17362|Ensembl:ENSG00000150347|Vega:OTTHUMG00000018298 +84162 KIAA1109 MIM:611565|HGNC:HGNC:26953|Ensembl:ENSG00000138688|Vega:OTTHUMG00000150116 +84163 GTF2IRD2 MIM:608899|HGNC:HGNC:30775|Ensembl:ENSG00000196275|Vega:OTTHUMG00000181527 +84164 ASCC2 MIM:614216|HGNC:HGNC:24103|Ensembl:ENSG00000100325|Vega:OTTHUMG00000067658 +84166 NLRC5 MIM:613537|HGNC:HGNC:29933|Ensembl:ENSG00000140853|Vega:OTTHUMG00000133470 +84167 C19orf44 HGNC:HGNC:26141|Ensembl:ENSG00000105072|Vega:OTTHUMG00000182439 +84168 ANTXR1 MIM:606410|HGNC:HGNC:21014|Ensembl:ENSG00000169604|Vega:OTTHUMG00000129575 +84171 LOXL4 MIM:607318|HGNC:HGNC:17171|Ensembl:ENSG00000138131|Vega:OTTHUMG00000018874 +84172 POLR1B MIM:602000|HGNC:HGNC:20454|Ensembl:ENSG00000125630|Vega:OTTHUMG00000131314 +84173 ELMOD3 MIM:615427|HGNC:HGNC:26158|Ensembl:ENSG00000115459|Vega:OTTHUMG00000130170 +84174 SLA2 MIM:606577|HGNC:HGNC:17329|Ensembl:ENSG00000101082|Vega:OTTHUMG00000032393 +84176 MYH16 MIM:608580|HGNC:HGNC:31038 +84179 MFSD7 HGNC:HGNC:26177|Ensembl:ENSG00000169026|Vega:OTTHUMG00000119001 +84181 CHD6 MIM:616114|HGNC:HGNC:19057|Ensembl:ENSG00000124177|Vega:OTTHUMG00000032487 +84182 MINDY4 HGNC:HGNC:21916|Ensembl:ENSG00000106125|Vega:OTTHUMG00000152800 +84186 ZCCHC7 HGNC:HGNC:26209|Ensembl:ENSG00000147905|Vega:OTTHUMG00000019915 +84187 TMEM164 HGNC:HGNC:26217|Ensembl:ENSG00000157600|Vega:OTTHUMG00000022192 +84188 FAR1 MIM:616107|HGNC:HGNC:26222|Ensembl:ENSG00000197601|Vega:OTTHUMG00000165743 +84189 SLITRK6 MIM:609681|HGNC:HGNC:23503|Ensembl:ENSG00000184564|Vega:OTTHUMG00000017157 +84190 METTL25 HGNC:HGNC:26228|Ensembl:ENSG00000127720|Vega:OTTHUMG00000170252 +84191 FAM96A HGNC:HGNC:26235|Ensembl:ENSG00000166797|Vega:OTTHUMG00000132961 +84193 SETD3 MIM:615671|HGNC:HGNC:20493|Ensembl:ENSG00000183576|Vega:OTTHUMG00000028970 +84196 USP48 MIM:617445|HGNC:HGNC:18533|Ensembl:ENSG00000090686|Vega:OTTHUMG00000007798 +84197 POMK MIM:615247|HGNC:HGNC:26267|Ensembl:ENSG00000185900|Vega:OTTHUMG00000164100 +84203 TXNDC2 HGNC:HGNC:16470|Ensembl:ENSG00000168454|Vega:OTTHUMG00000131602 +84206 MEX3B MIM:611008|HGNC:HGNC:25297|Ensembl:ENSG00000183496|Vega:OTTHUMG00000147356 +84210 ANKRD20A1 HGNC:HGNC:23665|Ensembl:ENSG00000260691|Vega:OTTHUMG00000188594 +84214 LOC84214 - +84215 ZNF541 HGNC:HGNC:25294|Ensembl:ENSG00000118156|Vega:OTTHUMG00000141262 +84216 TMEM117 HGNC:HGNC:25308|Ensembl:ENSG00000139173|Vega:OTTHUMG00000169427 +84217 ZMYND12 HGNC:HGNC:21192|Ensembl:ENSG00000066185|Vega:OTTHUMG00000007333 +84218 TBC1D3F MIM:610809|HGNC:HGNC:18257|Ensembl:ENSG00000275954|Vega:OTTHUMG00000188428 +84219 WDR24 HGNC:HGNC:20852|Ensembl:ENSG00000127580|Vega:OTTHUMG00000090421 +84220 RGPD5 MIM:612708|HGNC:HGNC:32418|Ensembl:ENSG00000015568|Vega:OTTHUMG00000130985 +84221 SPATC1L MIM:612412|HGNC:HGNC:1298|Ensembl:ENSG00000160284|Vega:OTTHUMG00000090487 +84222 TMEM191A HGNC:HGNC:25317|Ensembl:ENSG00000226287 +84223 IQCG MIM:612477|HGNC:HGNC:25251|Ensembl:ENSG00000114473|Vega:OTTHUMG00000155408 +84224 NBPF3 MIM:612992|HGNC:HGNC:25076|Ensembl:ENSG00000142794|Vega:OTTHUMG00000002944 +84225 ZMYND15 MIM:614312|HGNC:HGNC:20997|Ensembl:ENSG00000141497|Vega:OTTHUMG00000090760 +84226 C2orf16 HGNC:HGNC:25275|Ensembl:ENSG00000221843|Vega:OTTHUMG00000159099 +84229 DRC7 HGNC:HGNC:25289|Ensembl:ENSG00000159625|Vega:OTTHUMG00000133473 +84230 LRRC8C MIM:612889|HGNC:HGNC:25075|Ensembl:ENSG00000171488|Vega:OTTHUMG00000010305 +84231 TRAF7 MIM:606692|HGNC:HGNC:20456|Ensembl:ENSG00000131653|Vega:OTTHUMG00000128826 +84232 MAF1 MIM:610210|HGNC:HGNC:24966|Ensembl:ENSG00000179632|Vega:OTTHUMG00000165244 +84233 TMEM126A MIM:612988|HGNC:HGNC:25382|Ensembl:ENSG00000171202|Vega:OTTHUMG00000166975 +84236 RHBDD1 MIM:617515|HGNC:HGNC:23081|Ensembl:ENSG00000144468|Vega:OTTHUMG00000133178 +84239 ATP13A4 MIM:609556|HGNC:HGNC:25422|Ensembl:ENSG00000127249|Vega:OTTHUMG00000074067 +84240 ZCCHC9 HGNC:HGNC:25424|Ensembl:ENSG00000131732|Vega:OTTHUMG00000119014 +84243 ZDHHC18 HGNC:HGNC:20712|Ensembl:ENSG00000204160|Vega:OTTHUMG00000004092 +84245 MRI1 MIM:615105|HGNC:HGNC:28469|Ensembl:ENSG00000037757|Vega:OTTHUMG00000180867 +84246 MED10 MIM:612382|HGNC:HGNC:28760|Ensembl:ENSG00000133398|Vega:OTTHUMG00000161682 +84247 RTL6 HGNC:HGNC:13343|Ensembl:ENSG00000188636|Vega:OTTHUMG00000150465 +84248 FYTTD1 MIM:616933|HGNC:HGNC:25407|Ensembl:ENSG00000122068|Vega:OTTHUMG00000155453 +84249 PSD2 HGNC:HGNC:19092|Ensembl:ENSG00000146005|Vega:OTTHUMG00000129240 +84250 SLF1 HGNC:HGNC:25408|Ensembl:ENSG00000133302|Vega:OTTHUMG00000121133 +84251 SGIP1 MIM:611540|HGNC:HGNC:25412|Ensembl:ENSG00000118473|Vega:OTTHUMG00000009161 +84253 GARNL3 HGNC:HGNC:25425|Ensembl:ENSG00000136895|Vega:OTTHUMG00000020700 +84254 CAMKK1 MIM:611411|HGNC:HGNC:1469|Ensembl:ENSG00000004660|Vega:OTTHUMG00000090725 +84255 SLC37A3 HGNC:HGNC:20651|Ensembl:ENSG00000157800|Vega:OTTHUMG00000157343 +84256 FLYWCH1 HGNC:HGNC:25404|Ensembl:ENSG00000059122|Vega:OTTHUMG00000177364 +84258 SYT3 MIM:600327|HGNC:HGNC:11511|Ensembl:ENSG00000213023|Vega:OTTHUMG00000183064 +84259 DCUN1D5 MIM:616522|HGNC:HGNC:28409|Ensembl:ENSG00000137692|Vega:OTTHUMG00000165822 +84260 TCHP MIM:612654|HGNC:HGNC:28135|Ensembl:ENSG00000139437|Vega:OTTHUMG00000169281 +84261 FBXW9 MIM:609074|HGNC:HGNC:28136|Ensembl:ENSG00000132004|Vega:OTTHUMG00000150152 +84262 PSMG3 MIM:617528|HGNC:HGNC:22420|Ensembl:ENSG00000157778|Vega:OTTHUMG00000119043 +84263 HSDL2 HGNC:HGNC:18572|Ensembl:ENSG00000119471|Vega:OTTHUMG00000020504 +84264 HAGHL HGNC:HGNC:14177|Ensembl:ENSG00000103253|Vega:OTTHUMG00000170560 +84265 POLR3GL MIM:617457|HGNC:HGNC:28466|Ensembl:ENSG00000121851|Vega:OTTHUMG00000013739 +84266 ALKBH7 MIM:613305|HGNC:HGNC:21306|Ensembl:ENSG00000125652|Vega:OTTHUMG00000180792 +84267 C9orf64 MIM:611342|HGNC:HGNC:28144|Ensembl:ENSG00000165118|Vega:OTTHUMG00000020111 +84268 RPAIN MIM:617299|HGNC:HGNC:28641|Ensembl:ENSG00000129197|Vega:OTTHUMG00000177872 +84269 CHCHD5 MIM:616978|HGNC:HGNC:17840|Ensembl:ENSG00000125611|Vega:OTTHUMG00000131312 +84270 CARD19 HGNC:HGNC:28148|Ensembl:ENSG00000165233|Vega:OTTHUMG00000020243 +84271 POLDIP3 MIM:611520|HGNC:HGNC:23782|Ensembl:ENSG00000100227|Vega:OTTHUMG00000150887 +84272 YIPF4 MIM:617534|HGNC:HGNC:28145|Ensembl:ENSG00000119820|Vega:OTTHUMG00000128452 +84273 NOA1 MIM:614919|HGNC:HGNC:28473|Ensembl:ENSG00000084092|Vega:OTTHUMG00000128773 +84274 COQ5 MIM:616359|HGNC:HGNC:28722|Ensembl:ENSG00000110871|Vega:OTTHUMG00000169375 +84275 SLC25A33 MIM:610816|HGNC:HGNC:29681|Ensembl:ENSG00000171612|Vega:OTTHUMG00000001322 +84276 NICN1 MIM:611516|HGNC:HGNC:18317|Ensembl:ENSG00000145029|Ensembl:ENSG00000283189|Vega:OTTHUMG00000156848|Vega:OTTHUMG00000191676 +84277 DNAJC30 HGNC:HGNC:16410|Ensembl:ENSG00000176410|Vega:OTTHUMG00000023290 +84278 MFSD14C HGNC:HGNC:23672|Ensembl:ENSG00000196312|Vega:OTTHUMG00000020317 +84279 PRADC1 HGNC:HGNC:16047|Ensembl:ENSG00000135617|Vega:OTTHUMG00000129773 +84280 BTBD10 MIM:615933|HGNC:HGNC:21445|Ensembl:ENSG00000148925|Vega:OTTHUMG00000165787 +84281 C2orf88 MIM:615117|HGNC:HGNC:28191|Ensembl:ENSG00000187699|Vega:OTTHUMG00000154361 +84282 RNF135 MIM:611358|HGNC:HGNC:21158|Ensembl:ENSG00000181481|Vega:OTTHUMG00000132867 +84283 TMEM79 MIM:615531|HGNC:HGNC:28196|Ensembl:ENSG00000163472|Vega:OTTHUMG00000019788 +84284 NTPCR HGNC:HGNC:28204|Ensembl:ENSG00000135778|Vega:OTTHUMG00000037822 +84285 EIF1AD HGNC:HGNC:28147|Ensembl:ENSG00000175376|Vega:OTTHUMG00000166671 +84286 TMEM175 MIM:616660|HGNC:HGNC:28709|Ensembl:ENSG00000127419|Vega:OTTHUMG00000118996 +84287 ZDHHC16 MIM:616750|HGNC:HGNC:20714|Ensembl:ENSG00000171307|Vega:OTTHUMG00000018847 +84288 EFCAB2 HGNC:HGNC:28166|Ensembl:ENSG00000203666|Vega:OTTHUMG00000040474 +84289 ING5 MIM:608525|HGNC:HGNC:19421|Ensembl:ENSG00000168395|Vega:OTTHUMG00000151501 +84290 CAPNS2 MIM:616767|HGNC:HGNC:16371|Ensembl:ENSG00000256812|Vega:OTTHUMG00000167812 +84292 WDR83 MIM:616850|HGNC:HGNC:32672|Ensembl:ENSG00000123154|Vega:OTTHUMG00000169356 +84293 FAM213A MIM:617165|HGNC:HGNC:28651|Ensembl:ENSG00000122378|Vega:OTTHUMG00000018614 +84294 UTP23 HGNC:HGNC:28224|Ensembl:ENSG00000147679|Vega:OTTHUMG00000164958 +84295 PHF6 MIM:300414|HGNC:HGNC:18145|Ensembl:ENSG00000156531|Vega:OTTHUMG00000022453 +84296 GINS4 MIM:610611|HGNC:HGNC:28226|Ensembl:ENSG00000147536|Vega:OTTHUMG00000164079 +84298 LLPH MIM:616998|HGNC:HGNC:28229|Ensembl:ENSG00000139233|Vega:OTTHUMG00000168959 +84299 MIEN1 MIM:611802|HGNC:HGNC:28230|Ensembl:ENSG00000141741|Vega:OTTHUMG00000133252 +84300 UQCC2 MIM:614461|HGNC:HGNC:21237|Ensembl:ENSG00000137288|Vega:OTTHUMG00000014534 +84301 DDI2 HGNC:HGNC:24578|Ensembl:ENSG00000197312|Vega:OTTHUMG00000002381 +84302 TMEM246 HGNC:HGNC:28180|Ensembl:ENSG00000165152|Vega:OTTHUMG00000020381 +84303 CHCHD6 MIM:615634|HGNC:HGNC:28184|Ensembl:ENSG00000159685|Vega:OTTHUMG00000159601 +84304 NUDT22 HGNC:HGNC:28189|Ensembl:ENSG00000149761|Vega:OTTHUMG00000167791 +84305 PYM1 HGNC:HGNC:30258|Ensembl:ENSG00000170473|Vega:OTTHUMG00000170220 +84306 PDCD2L MIM:615661|HGNC:HGNC:28194|Ensembl:ENSG00000126249|Vega:OTTHUMG00000182089 +84307 ZNF397 MIM:609601|HGNC:HGNC:18818|Ensembl:ENSG00000186812|Vega:OTTHUMG00000178532 +84309 NUDT16L1 MIM:617338|HGNC:HGNC:28154|Ensembl:ENSG00000168101|Vega:OTTHUMG00000129471 +84310 C7orf50 HGNC:HGNC:22421|Ensembl:ENSG00000146540|Vega:OTTHUMG00000151477 +84311 MRPL45 MIM:611850|HGNC:HGNC:16651|Ensembl:ENSG00000278845|Vega:OTTHUMG00000188489 +84312 BRMS1L HGNC:HGNC:20512|Ensembl:ENSG00000100916|Vega:OTTHUMG00000170559 +84313 VPS25 MIM:610907|HGNC:HGNC:28122|Ensembl:ENSG00000131475|Vega:OTTHUMG00000180649 +84314 TMEM107 MIM:616183|HGNC:HGNC:28128|Ensembl:ENSG00000179029|Vega:OTTHUMG00000166276 +84315 MON1A MIM:611464|HGNC:HGNC:28207|Ensembl:ENSG00000164077|Vega:OTTHUMG00000156737 +84316 NAA38 HGNC:HGNC:28212|Ensembl:ENSG00000183011|Vega:OTTHUMG00000178023 +84317 CCDC115 MIM:613734|HGNC:HGNC:28178|Ensembl:ENSG00000136710|Vega:OTTHUMG00000131631 +84318 CCDC77 HGNC:HGNC:28203|Ensembl:ENSG00000120647|Vega:OTTHUMG00000129214 +84319 CMSS1 HGNC:HGNC:28666|Ensembl:ENSG00000184220|Vega:OTTHUMG00000159054 +84320 ACBD6 MIM:616352|HGNC:HGNC:23339|Ensembl:ENSG00000230124|Vega:OTTHUMG00000035117 +84321 THOC3 MIM:606929|HGNC:HGNC:19072|Ensembl:ENSG00000051596|Vega:OTTHUMG00000130658 +84322 C18orf12 HGNC:HGNC:24918 +84324 SARNP MIM:610049|HGNC:HGNC:24432|Ensembl:ENSG00000205323|Vega:OTTHUMG00000170441 +84326 METTL26 HGNC:HGNC:14141|Ensembl:ENSG00000130731|Vega:OTTHUMG00000047855 +84327 ZBED3 MIM:615250|HGNC:HGNC:20711|Ensembl:ENSG00000132846|Vega:OTTHUMG00000102131 +84328 LZIC MIM:610458|HGNC:HGNC:17497|Ensembl:ENSG00000162441|Vega:OTTHUMG00000001804 +84329 HVCN1 MIM:611227|HGNC:HGNC:28240|Ensembl:ENSG00000122986|Vega:OTTHUMG00000169530 +84330 ZNF414 HGNC:HGNC:20630|Ensembl:ENSG00000133250|Vega:OTTHUMG00000182240 +84331 MCRIP2 HGNC:HGNC:14142|Ensembl:ENSG00000172366|Vega:OTTHUMG00000048042 +84332 DYDC2 HGNC:HGNC:23468|Ensembl:ENSG00000133665|Vega:OTTHUMG00000018610 +84333 PCGF5 MIM:617407|HGNC:HGNC:28264|Ensembl:ENSG00000180628|Vega:OTTHUMG00000018740 +84334 APOPT1 MIM:616003|HGNC:HGNC:20492|Ensembl:ENSG00000256053|Vega:OTTHUMG00000153929 +84335 AKT1S1 MIM:610221|HGNC:HGNC:28426|Ensembl:ENSG00000204673|Vega:OTTHUMG00000150246 +84336 TMEM101 HGNC:HGNC:28653|Ensembl:ENSG00000091947|Vega:OTTHUMG00000181803 +84337 ELOF1 HGNC:HGNC:28691|Ensembl:ENSG00000130165|Vega:OTTHUMG00000182034 +84340 GFM2 MIM:606544|HGNC:HGNC:29682|Ensembl:ENSG00000164347|Vega:OTTHUMG00000102058 +84342 COG8 MIM:606979|HGNC:HGNC:18623|Ensembl:ENSG00000213380|Ensembl:ENSG00000272617|Vega:OTTHUMG00000154277|Vega:OTTHUMG00000186023 +84343 HPS3 MIM:606118|HGNC:HGNC:15597|Ensembl:ENSG00000163755|Vega:OTTHUMG00000159548 +84364 ARFGAP2 MIM:606908|HGNC:HGNC:13504|Ensembl:ENSG00000149182|Vega:OTTHUMG00000166773 +84365 NIFK MIM:611970|HGNC:HGNC:17838|Ensembl:ENSG00000155438|Vega:OTTHUMG00000131442 +84366 PRAC1 MIM:609819|HGNC:HGNC:30591|Ensembl:ENSG00000159182|Vega:OTTHUMG00000159899 +84376 HOOK3 MIM:607825|HGNC:HGNC:23576|Ensembl:ENSG00000168172|Vega:OTTHUMG00000165278 +84417 C2orf40 MIM:611752|HGNC:HGNC:24642|Ensembl:ENSG00000119147|Vega:OTTHUMG00000130921 +84418 CYSTM1 HGNC:HGNC:30239|Ensembl:ENSG00000120306|Vega:OTTHUMG00000129243 +84419 C15orf48 MIM:608409|HGNC:HGNC:29898|Ensembl:ENSG00000166920|Vega:OTTHUMG00000131424 +84432 PROK1 MIM:606233|HGNC:HGNC:18454|Ensembl:ENSG00000143125|Vega:OTTHUMG00000011569 +84433 CARD11 MIM:607210|HGNC:HGNC:16393|Ensembl:ENSG00000198286|Vega:OTTHUMG00000023023 +84434 THCYTX MIM:300331 +84435 ADGRA1 MIM:612302|HGNC:HGNC:13838|Ensembl:ENSG00000197177|Vega:OTTHUMG00000019304 +84436 ZNF528 MIM:615580|HGNC:HGNC:29384|Ensembl:ENSG00000167555|Vega:OTTHUMG00000156494 +84437 MSANTD4 HGNC:HGNC:29383|Ensembl:ENSG00000170903|Vega:OTTHUMG00000166240 +84439 HHIPL1 HGNC:HGNC:19710|Ensembl:ENSG00000182218|Vega:OTTHUMG00000171509 +84440 RAB11FIP4 MIM:611999|HGNC:HGNC:30267|Ensembl:ENSG00000131242|Vega:OTTHUMG00000132787 +84441 MAML2 MIM:607537|HGNC:HGNC:16259|Ensembl:ENSG00000184384|Vega:OTTHUMG00000167677 +84443 FRMPD3 HGNC:HGNC:29382|Ensembl:ENSG00000147234|Vega:OTTHUMG00000022165 +84444 DOT1L MIM:607375|HGNC:HGNC:24948|Ensembl:ENSG00000104885|Vega:OTTHUMG00000150431 +84445 LZTS2 MIM:610454|HGNC:HGNC:29381|Ensembl:ENSG00000107816|Vega:OTTHUMG00000018914 +84446 BRSK1 MIM:609235|HGNC:HGNC:18994|Ensembl:ENSG00000160469|Vega:OTTHUMG00000180735 +84447 SYVN1 MIM:608046|HGNC:HGNC:20738|Ensembl:ENSG00000162298|Vega:OTTHUMG00000165607 +84448 ABLIM2 MIM:612544|HGNC:HGNC:19195|Ensembl:ENSG00000163995|Vega:OTTHUMG00000057427 +84449 ZNF333 MIM:611811|HGNC:HGNC:15624|Ensembl:ENSG00000160961|Vega:OTTHUMG00000183407 +84450 ZNF512 HGNC:HGNC:29380|Ensembl:ENSG00000243943|Vega:OTTHUMG00000097786 +84451 MAP3K21 MIM:614793|HGNC:HGNC:29798|Ensembl:ENSG00000143674|Vega:OTTHUMG00000037889 +84455 EFCAB7 HGNC:HGNC:29379|Ensembl:ENSG00000203965|Vega:OTTHUMG00000008983 +84456 L3MBTL3 HGNC:HGNC:23035|Ensembl:ENSG00000198945|Vega:OTTHUMG00000015554 +84457 PHYHIPL HGNC:HGNC:29378|Ensembl:ENSG00000165443|Vega:OTTHUMG00000018276 +84458 LCOR MIM:607698|HGNC:HGNC:29503|Ensembl:ENSG00000196233|Vega:OTTHUMG00000018841 +84460 ZMAT1 HGNC:HGNC:29377|Ensembl:ENSG00000166432|Vega:OTTHUMG00000022044 +84461 NEURL4 MIM:615865|HGNC:HGNC:34410|Ensembl:ENSG00000215041|Vega:OTTHUMG00000132319 +84464 SLX4 MIM:613278|HGNC:HGNC:23845|Ensembl:ENSG00000188827|Vega:OTTHUMG00000074089 +84465 MEGF11 MIM:612454|HGNC:HGNC:29635|Ensembl:ENSG00000157890|Vega:OTTHUMG00000133175 +84466 MEGF10 MIM:612453|HGNC:HGNC:29634|Ensembl:ENSG00000145794|Vega:OTTHUMG00000128984 +84467 FBN3 MIM:608529|HGNC:HGNC:18794|Ensembl:ENSG00000142449|Vega:OTTHUMG00000182462 +84498 FAM120B MIM:612266|HGNC:HGNC:21109|Ensembl:ENSG00000112584|Vega:OTTHUMG00000016080 +84501 SPIRE2 MIM:609217|HGNC:HGNC:30623|Ensembl:ENSG00000204991|Vega:OTTHUMG00000173039 +84502 JPH4 HGNC:HGNC:20156|Ensembl:ENSG00000092051|Vega:OTTHUMG00000028769 +84503 ZNF527 HGNC:HGNC:29385|Ensembl:ENSG00000189164|Vega:OTTHUMG00000048173 +84504 NKX6-2 MIM:605955|HGNC:HGNC:19321|Ensembl:ENSG00000148826|Vega:OTTHUMG00000019294 +84513 PLPP5 MIM:610626|HGNC:HGNC:25026|Ensembl:ENSG00000147535|Vega:OTTHUMG00000165104 +84514 GHDC MIM:608587|HGNC:HGNC:24438|Ensembl:ENSG00000167925|Vega:OTTHUMG00000180108 +84515 MCM8 MIM:608187|HGNC:HGNC:16147|Ensembl:ENSG00000125885|Vega:OTTHUMG00000031822 +84516 DCTN5 MIM:612962|HGNC:HGNC:24594|Ensembl:ENSG00000166847|Vega:OTTHUMG00000131610 +84517 ACTRT3 MIM:608534|HGNC:HGNC:24022|Ensembl:ENSG00000184378|Vega:OTTHUMG00000184025 +84518 CNFN MIM:611764|HGNC:HGNC:30183|Ensembl:ENSG00000105427|Vega:OTTHUMG00000182813 +84519 ACRBP MIM:608352|HGNC:HGNC:17195|Ensembl:ENSG00000111644|Vega:OTTHUMG00000168715 +84520 GON7 MIM:617436|HGNC:HGNC:20356|Ensembl:ENSG00000170270|Vega:OTTHUMG00000171267 +84522 JAGN1 MIM:616012|HGNC:HGNC:26926|Ensembl:ENSG00000171135|Vega:OTTHUMG00000128523 +84524 ZC3H8 HGNC:HGNC:30941|Ensembl:ENSG00000144161|Vega:OTTHUMG00000153270 +84525 HOPX MIM:607275|HGNC:HGNC:24961|Ensembl:ENSG00000171476|Vega:OTTHUMG00000128768 +84527 ZNF559 HGNC:HGNC:28197|Ensembl:ENSG00000188321|Ensembl:ENSG00000270011|Vega:OTTHUMG00000179942|Vega:OTTHUMG00000183958 +84528 RHOXF2 MIM:300447|HGNC:HGNC:30011|Ensembl:ENSG00000131721|Vega:OTTHUMG00000022296 +84529 C15orf41 MIM:615626|HGNC:HGNC:26929|Ensembl:ENSG00000186073|Vega:OTTHUMG00000172659 +84530 SRRM4 MIM:613103|HGNC:HGNC:29389|Ensembl:ENSG00000139767|Vega:OTTHUMG00000168928 +84532 ACSS1 MIM:614355|HGNC:HGNC:16091|Ensembl:ENSG00000154930|Vega:OTTHUMG00000032112 +84536 LINC01547 HGNC:HGNC:15707|Ensembl:ENSG00000183250 +84539 MCHR2 MIM:606111|HGNC:HGNC:20867|Ensembl:ENSG00000152034|Vega:OTTHUMG00000015270 +84541 KBTBD8 MIM:616607|HGNC:HGNC:30691|Ensembl:ENSG00000163376|Vega:OTTHUMG00000158779 +84542 KIAA1841 HGNC:HGNC:29387|Ensembl:ENSG00000162929|Vega:OTTHUMG00000187089 +84545 MRPL43 MIM:611848|HGNC:HGNC:14517|Ensembl:ENSG00000055950|Vega:OTTHUMG00000018920 +84546 SNORD35B HGNC:HGNC:17365|Ensembl:ENSG00000200530 +84547 PGBD1 HGNC:HGNC:19398|Ensembl:ENSG00000137338|Vega:OTTHUMG00000014520 +84548 TMEM185A MIM:300031|HGNC:HGNC:17125|Ensembl:ENSG00000269556|Vega:OTTHUMG00000022625 +84549 MAK16 HGNC:HGNC:13703|Ensembl:ENSG00000198042|Vega:OTTHUMG00000163957 +84552 PARD6G MIM:608976|HGNC:HGNC:16076|Ensembl:ENSG00000178184|Vega:OTTHUMG00000132922 +84553 FAXC HGNC:HGNC:20742|Ensembl:ENSG00000146267|Vega:OTTHUMG00000015261 +84557 MAP1LC3A MIM:601242|HGNC:HGNC:6838|Ensembl:ENSG00000101460|Vega:OTTHUMG00000032306 +84559 GOLGA2P2Y MIM:400035|HGNC:HGNC:16479|Ensembl:ENSG00000239533 +84560 MT4 MIM:606206|HGNC:HGNC:18705|Ensembl:ENSG00000102891|Vega:OTTHUMG00000176863 +84561 SLC12A8 MIM:611316|HGNC:HGNC:15595|Ensembl:ENSG00000221955|Vega:OTTHUMG00000159483 +84565 LCS1 MIM:214900|HGNC:HGNC:15737 +84569 LYZL1 HGNC:HGNC:30502|Ensembl:ENSG00000120563|Vega:OTTHUMG00000017880 +84570 COL25A1 MIM:610004|HGNC:HGNC:18603|Ensembl:ENSG00000188517|Vega:OTTHUMG00000150039 +84572 GNPTG MIM:607838|HGNC:HGNC:23026|Ensembl:ENSG00000090581|Vega:OTTHUMG00000047835 +84612 PARD6B MIM:608975|HGNC:HGNC:16245|Ensembl:ENSG00000124171|Vega:OTTHUMG00000032732 +84614 ZBTB37 HGNC:HGNC:28365|Ensembl:ENSG00000185278|Vega:OTTHUMG00000037274 +84616 KRTAP4-4 HGNC:HGNC:16928|Ensembl:ENSG00000171396|Vega:OTTHUMG00000133428 +84617 TUBB6 MIM:615103|HGNC:HGNC:20776|Ensembl:ENSG00000176014|Vega:OTTHUMG00000131692 +84618 NT5C1A MIM:610525|HGNC:HGNC:17819|Ensembl:ENSG00000116981|Vega:OTTHUMG00000009244 +84619 ZGPAT HGNC:HGNC:15948|Ensembl:ENSG00000197114|Ensembl:ENSG00000273154|Vega:OTTHUMG00000032998|Vega:OTTHUMG00000186489 +84620 ST6GAL2 MIM:608472|HGNC:HGNC:10861|Ensembl:ENSG00000144057|Vega:OTTHUMG00000130923 +84622 ZNF594 HGNC:HGNC:29392|Ensembl:ENSG00000180626|Vega:OTTHUMG00000132059 +84623 KIRREL3 MIM:607761|HGNC:HGNC:23204|Ensembl:ENSG00000149571|Vega:OTTHUMG00000165831 +84624 FNDC1 MIM:609991|HGNC:HGNC:21184|Ensembl:ENSG00000164694|Vega:OTTHUMG00000015927 +84626 KRBA1 HGNC:HGNC:22228|Ensembl:ENSG00000133619|Vega:OTTHUMG00000157886 +84627 ZNF469 MIM:612078|HGNC:HGNC:23216|Ensembl:ENSG00000225614|Vega:OTTHUMG00000173151 +84628 NTNG2 HGNC:HGNC:14288|Ensembl:ENSG00000196358|Vega:OTTHUMG00000020835 +84629 TNRC18 HGNC:HGNC:11962|Ensembl:ENSG00000182095|Vega:OTTHUMG00000151831 +84630 TTBK1 HGNC:HGNC:19140|Ensembl:ENSG00000146216|Vega:OTTHUMG00000014725 +84631 SLITRK2 MIM:300561|HGNC:HGNC:13449|Ensembl:ENSG00000185985|Vega:OTTHUMG00000022595 +84632 AFAP1L2 MIM:612420|HGNC:HGNC:25901|Ensembl:ENSG00000169129|Vega:OTTHUMG00000019086 +84634 KISS1R MIM:604161|HGNC:HGNC:4510|Ensembl:ENSG00000116014|Vega:OTTHUMG00000181900 +84636 GPR174 MIM:300903|HGNC:HGNC:30245|Ensembl:ENSG00000147138|Vega:OTTHUMG00000021898 +84639 IL1F10 MIM:615296|HGNC:HGNC:15552|Ensembl:ENSG00000136697|Vega:OTTHUMG00000131339 +84640 USP38 HGNC:HGNC:20067|Ensembl:ENSG00000170185|Vega:OTTHUMG00000161420 +84641 MFSD14B HGNC:HGNC:23376|Ensembl:ENSG00000148110|Vega:OTTHUMG00000020265 +84643 KIF2B MIM:615142|HGNC:HGNC:29443|Ensembl:ENSG00000141200|Vega:OTTHUMG00000177756 +84645 C22orf23 HGNC:HGNC:18589|Ensembl:ENSG00000128346|Vega:OTTHUMG00000150672 +84647 PLA2G12B MIM:611653|HGNC:HGNC:18555|Ensembl:ENSG00000138308|Vega:OTTHUMG00000018446 +84648 LCE3D MIM:612616|HGNC:HGNC:16615|Ensembl:ENSG00000163202|Vega:OTTHUMG00000012384 +84649 DGAT2 MIM:606983|HGNC:HGNC:16940|Ensembl:ENSG00000062282|Vega:OTTHUMG00000165338 +84650 EBPL MIM:617335|HGNC:HGNC:18061|Ensembl:ENSG00000123179|Vega:OTTHUMG00000016920 +84651 SPINK7 MIM:617288|HGNC:HGNC:24643|Ensembl:ENSG00000145879|Vega:OTTHUMG00000163522 +84654 SPZ1 HGNC:HGNC:30721|Ensembl:ENSG00000164299|Vega:OTTHUMG00000162514 +84656 GLYR1 MIM:610660|HGNC:HGNC:24434|Ensembl:ENSG00000140632|Vega:OTTHUMG00000129530 +84657 LINC00852 HGNC:HGNC:29904|Ensembl:ENSG00000231177 +84658 ADGRE3 MIM:606101|HGNC:HGNC:23647|Ensembl:ENSG00000131355|Vega:OTTHUMG00000183406 +84659 RNASE7 MIM:612484|HGNC:HGNC:19278|Ensembl:ENSG00000165799|Vega:OTTHUMG00000171358 +84660 CCDC62 MIM:613481|HGNC:HGNC:30723|Ensembl:ENSG00000130783|Vega:OTTHUMG00000168764 +84661 DPY30 MIM:612032|HGNC:HGNC:24590|Ensembl:ENSG00000162961|Vega:OTTHUMG00000128457 +84662 GLIS2 MIM:608539|HGNC:HGNC:29450|Ensembl:ENSG00000126603|Vega:OTTHUMG00000129467 +84664 CSPG4P2Y HGNC:HGNC:32424 +84665 MYPN MIM:608517|HGNC:HGNC:23246|Ensembl:ENSG00000138347|Vega:OTTHUMG00000018344 +84666 RETNLB MIM:605645|HGNC:HGNC:20388|Ensembl:ENSG00000163515|Vega:OTTHUMG00000159393 +84667 HES7 MIM:608059|HGNC:HGNC:15977|Ensembl:ENSG00000179111|Vega:OTTHUMG00000178316 +84668 FAM126A MIM:610531|HGNC:HGNC:24587|Ensembl:ENSG00000122591|Vega:OTTHUMG00000128435 +84669 USP32 MIM:607740|HGNC:HGNC:19143|Ensembl:ENSG00000170832|Vega:OTTHUMG00000180001 +84671 ZNF347 HGNC:HGNC:16447|Ensembl:ENSG00000197937|Vega:OTTHUMG00000182883 +84672 TTTY6 MIM:400039|HGNC:HGNC:16483|Ensembl:ENSG00000131538 +84673 TTTY8 HGNC:HGNC:18489|Ensembl:ENSG00000183385 +84674 CARD6 MIM:609986|HGNC:HGNC:16394|Ensembl:ENSG00000132357|Vega:OTTHUMG00000094775 +84675 TRIM55 MIM:606469|HGNC:HGNC:14215|Ensembl:ENSG00000147573|Vega:OTTHUMG00000164473 +84676 TRIM63 MIM:606131|HGNC:HGNC:16007|Ensembl:ENSG00000158022|Vega:OTTHUMG00000007510 +84677 DSCR8 MIM:613396|HGNC:HGNC:16707|Ensembl:ENSG00000198054|Vega:OTTHUMG00000090610 +84678 KDM2B MIM:609078|HGNC:HGNC:13610|Ensembl:ENSG00000089094|Vega:OTTHUMG00000169071 +84679 SLC9A7 MIM:300368|HGNC:HGNC:17123|Ensembl:ENSG00000065923|Vega:OTTHUMG00000021428 +84680 ACCS MIM:608405|HGNC:HGNC:23989|Ensembl:ENSG00000110455|Vega:OTTHUMG00000166427 +84681 HINT2 MIM:609997|HGNC:HGNC:18344|Ensembl:ENSG00000137133|Vega:OTTHUMG00000019886 +84684 INSM2 MIM:614027|HGNC:HGNC:17539|Ensembl:ENSG00000168348|Vega:OTTHUMG00000140223 +84687 PPP1R9B MIM:603325|HGNC:HGNC:9298|Ensembl:ENSG00000108819|Vega:OTTHUMG00000162008 +84688 C9orf24 HGNC:HGNC:19919|Ensembl:ENSG00000164972|Vega:OTTHUMG00000000437 +84689 MS4A14 HGNC:HGNC:30706|Ensembl:ENSG00000166928|Vega:OTTHUMG00000167357 +84690 SPATA22 HGNC:HGNC:30705|Ensembl:ENSG00000141255|Vega:OTTHUMG00000177609 +84691 FAM71F1 HGNC:HGNC:30704|Ensembl:ENSG00000135248|Vega:OTTHUMG00000158276 +84692 CCDC54 HGNC:HGNC:30703|Ensembl:ENSG00000138483|Vega:OTTHUMG00000159169 +84693 MCEE MIM:608419|HGNC:HGNC:16732|Ensembl:ENSG00000124370|Vega:OTTHUMG00000129709 +84694 GJA10 MIM:611924|HGNC:HGNC:16995|Ensembl:ENSG00000135355|Vega:OTTHUMG00000015210 +84695 LOXL3 MIM:607163|HGNC:HGNC:13869|Ensembl:ENSG00000115318|Vega:OTTHUMG00000129953 +84696 ABHD1 MIM:612195|HGNC:HGNC:17553|Ensembl:ENSG00000143994|Vega:OTTHUMG00000097072 +84698 CAPS2 MIM:607724|HGNC:HGNC:16471|Ensembl:ENSG00000180881|Vega:OTTHUMG00000152787 +84699 CREB3L3 MIM:611998|HGNC:HGNC:18855|Ensembl:ENSG00000060566|Vega:OTTHUMG00000181846 +84700 MYO18B MIM:607295|HGNC:HGNC:18150|Ensembl:ENSG00000133454|Vega:OTTHUMG00000151129 +84701 COX4I2 MIM:607976|HGNC:HGNC:16232|Ensembl:ENSG00000131055|Vega:OTTHUMG00000032180 +84705 GTPBP3 MIM:608536|HGNC:HGNC:14880|Ensembl:ENSG00000130299|Vega:OTTHUMG00000182766 +84706 GPT2 MIM:138210|HGNC:HGNC:18062|Ensembl:ENSG00000166123|Vega:OTTHUMG00000132541 +84707 BEX2 MIM:300691|HGNC:HGNC:30933|Ensembl:ENSG00000133134|Vega:OTTHUMG00000022095 +84708 LNX1 MIM:609732|HGNC:HGNC:6657|Ensembl:ENSG00000072201|Vega:OTTHUMG00000102099 +84709 MGARP HGNC:HGNC:29969|Ensembl:ENSG00000137463|Vega:OTTHUMG00000161325 +84717 HDGFL2 HGNC:HGNC:14680|Ensembl:ENSG00000167674|Vega:OTTHUMG00000182007 +84719 LINC00260 HGNC:HGNC:28770 +84720 PIGO MIM:614730|HGNC:HGNC:23215|Ensembl:ENSG00000165282|Vega:OTTHUMG00000019854 +84722 PSRC1 MIM:613126|HGNC:HGNC:24472|Ensembl:ENSG00000134222|Vega:OTTHUMG00000012000 +84725 PLEKHA8 MIM:608639|HGNC:HGNC:30037|Ensembl:ENSG00000106086|Vega:OTTHUMG00000097751 +84726 PRRC2B HGNC:HGNC:28121|Ensembl:ENSG00000130723 +84727 SPSB2 MIM:611658|HGNC:HGNC:29522|Ensembl:ENSG00000111671|Vega:OTTHUMG00000156665 +84733 CBX2 MIM:602770|HGNC:HGNC:1552|Ensembl:ENSG00000173894|Vega:OTTHUMG00000177463 +84734 FAM167B HGNC:HGNC:28133|Ensembl:ENSG00000183615|Vega:OTTHUMG00000007462 +84735 CNDP1 MIM:609064|HGNC:HGNC:20675|Ensembl:ENSG00000150656|Vega:OTTHUMG00000132852 +84740 AFAP1-AS1 HGNC:HGNC:28141|Ensembl:ENSG00000272620 +84747 UNC119B HGNC:HGNC:16488|Ensembl:ENSG00000175970|Vega:OTTHUMG00000169201 +84749 USP30 MIM:612492|HGNC:HGNC:20065|Ensembl:ENSG00000135093|Vega:OTTHUMG00000133613 +84750 FUT10 MIM:616931|HGNC:HGNC:19234|Ensembl:ENSG00000172728|Vega:OTTHUMG00000163954 +84752 B3GNT9 HGNC:HGNC:28714|Ensembl:ENSG00000237172|Vega:OTTHUMG00000173315 +84759 PCGF1 MIM:610231|HGNC:HGNC:17615|Ensembl:ENSG00000115289|Vega:OTTHUMG00000129954 +84765 ZNF577 HGNC:HGNC:28673|Ensembl:ENSG00000161551 +84766 CRACR2A MIM:614178|HGNC:HGNC:28657|Ensembl:ENSG00000130038|Vega:OTTHUMG00000168185 +84767 TRIM51 HGNC:HGNC:19023|Ensembl:ENSG00000124900|Vega:OTTHUMG00000156437 +84769 MPV17L2 MIM:616133|HGNC:HGNC:28177|Ensembl:ENSG00000254858|Vega:OTTHUMG00000165628 +84771 DDX11L2 HGNC:HGNC:37103 +84775 ZNF607 HGNC:HGNC:28192|Ensembl:ENSG00000198182|Vega:OTTHUMG00000182108 +84777 DLGAP1-AS2 HGNC:HGNC:28146 +84779 NAA11 HGNC:HGNC:28125|Ensembl:ENSG00000156269|Vega:OTTHUMG00000160913 +84787 KMT5C MIM:613198|HGNC:HGNC:28405|Ensembl:ENSG00000133247|Vega:OTTHUMG00000150483 +84789 MGC2889 - +84790 TUBA1C HGNC:HGNC:20768|Ensembl:ENSG00000167553|Vega:OTTHUMG00000169497 +84791 LINC00467 HGNC:HGNC:28227 +84792 FAM220A MIM:616628|HGNC:HGNC:22422|Ensembl:ENSG00000178397|Vega:OTTHUMG00000122091 +84793 FOXD2-AS1 HGNC:HGNC:44256|Ensembl:ENSG00000237424 +84795 PYROXD2 HGNC:HGNC:23517|Ensembl:ENSG00000119943|Vega:OTTHUMG00000018877 +84798 C19orf48 HGNC:HGNC:29667|Ensembl:ENSG00000167747|Vega:OTTHUMG00000182875 +84803 GPAT3 MIM:610958|HGNC:HGNC:28157|Ensembl:ENSG00000138678|Vega:OTTHUMG00000130431 +84804 MFSD9 HGNC:HGNC:28158|Ensembl:ENSG00000135953|Vega:OTTHUMG00000130781 +84807 NFKBID HGNC:HGNC:15671|Ensembl:ENSG00000167604|Vega:OTTHUMG00000180760 +84808 PERM1 MIM:615921|HGNC:HGNC:28208|Ensembl:ENSG00000187642|Vega:OTTHUMG00000040757 +84809 CROCCP2 HGNC:HGNC:28170|Ensembl:ENSG00000215908 +84811 BUD13 HGNC:HGNC:28199|Ensembl:ENSG00000137656|Vega:OTTHUMG00000045136 +84812 PLCD4 MIM:605939|HGNC:HGNC:9062|Ensembl:ENSG00000115556|Vega:OTTHUMG00000154743 +84814 PLPP7 HGNC:HGNC:28174|Ensembl:ENSG00000160539|Vega:OTTHUMG00000020822 +84815 MGC12916 Ensembl:ENSG00000266709 +84816 RTN4IP1 MIM:610502|HGNC:HGNC:18647|Ensembl:ENSG00000130347|Vega:OTTHUMG00000015304 +84817 TXNDC17 MIM:616967|HGNC:HGNC:28218|Ensembl:ENSG00000129235|Vega:OTTHUMG00000102053 +84818 IL17RC MIM:610925|HGNC:HGNC:18358|Ensembl:ENSG00000163702|Vega:OTTHUMG00000128648 +84820 POLR2J4 HGNC:HGNC:28195|Ensembl:ENSG00000214783 +84823 LMNB2 MIM:150341|HGNC:HGNC:6638|Ensembl:ENSG00000176619|Vega:OTTHUMG00000150626 +84824 FCRLA MIM:606891|HGNC:HGNC:18504|Ensembl:ENSG00000132185|Vega:OTTHUMG00000034537 +84826 SFT2D3 HGNC:HGNC:28767|Ensembl:ENSG00000173349|Vega:OTTHUMG00000131532 +84830 ADTRP MIM:614348|HGNC:HGNC:21214|Ensembl:ENSG00000111863|Vega:OTTHUMG00000014260 +84832 ANKRD36BP1 HGNC:HGNC:28169|Ensembl:ENSG00000214262 +84833 USMG5 MIM:615204|HGNC:HGNC:30889|Ensembl:ENSG00000173915|Vega:OTTHUMG00000018984 +84836 ABHD14B HGNC:HGNC:28235|Ensembl:ENSG00000114779|Vega:OTTHUMG00000157816 +84837 ARHGAP5-AS1 HGNC:HGNC:20279 +84838 ZNF496 MIM:613911|HGNC:HGNC:23713|Ensembl:ENSG00000162714|Vega:OTTHUMG00000041164 +84839 RAX2 MIM:610362|HGNC:HGNC:18286|Ensembl:ENSG00000173976|Vega:OTTHUMG00000171148 +84842 HPDL HGNC:HGNC:28242|Ensembl:ENSG00000186603|Vega:OTTHUMG00000007681 +84844 PHF5A HGNC:HGNC:18000|Ensembl:ENSG00000100410|Vega:OTTHUMG00000150966 +84847 LINC00525 HGNC:HGNC:40290|Ensembl:ENSG00000146666 +84848 MIR503HG HGNC:HGNC:28258|Ensembl:ENSG00000223749 +84850 GLIS3-AS1 HGNC:HGNC:28260|Ensembl:ENSG00000237009 +84851 TRIM52 HGNC:HGNC:19024|Ensembl:ENSG00000183718|Vega:OTTHUMG00000130964 +84852 ATP1A1-AS1 HGNC:HGNC:28262|Ensembl:ENSG00000203865 +84856 LINC00839 HGNC:HGNC:28269|Ensembl:ENSG00000185904 +84858 ZNF503 MIM:613902|HGNC:HGNC:23589|Ensembl:ENSG00000165655|Vega:OTTHUMG00000018526 +84859 LRCH3 HGNC:HGNC:28637|Ensembl:ENSG00000186001|Vega:OTTHUMG00000155378 +84861 KLHL22 HGNC:HGNC:25888|Ensembl:ENSG00000099910|Vega:OTTHUMG00000188269 +84864 RIOX2 MIM:612049|HGNC:HGNC:19441|Ensembl:ENSG00000170854|Vega:OTTHUMG00000160107 +84865 CCDC142 HGNC:HGNC:25889|Ensembl:ENSG00000135637|Vega:OTTHUMG00000129962 +84866 TMEM25 MIM:613934|HGNC:HGNC:25890|Ensembl:ENSG00000149582|Vega:OTTHUMG00000166339 +84867 PTPN5 MIM:176879|HGNC:HGNC:9657|Ensembl:ENSG00000110786|Vega:OTTHUMG00000134304 +84868 HAVCR2 MIM:606652|HGNC:HGNC:18437|Ensembl:ENSG00000135077|Vega:OTTHUMG00000130249 +84869 CBR4 HGNC:HGNC:25891|Ensembl:ENSG00000145439|Vega:OTTHUMG00000161025 +84870 RSPO3 MIM:610574|HGNC:HGNC:20866|Ensembl:ENSG00000146374|Vega:OTTHUMG00000015521 +84871 AGBL4 MIM:616476|HGNC:HGNC:25892|Ensembl:ENSG00000186094|Vega:OTTHUMG00000007793 +84872 ZC3H10 HGNC:HGNC:25893|Ensembl:ENSG00000135482|Vega:OTTHUMG00000170184 +84873 ADGRG7 MIM:612307|HGNC:HGNC:19241|Ensembl:ENSG00000144820|Vega:OTTHUMG00000159083 +84874 ZNF514 HGNC:HGNC:25894|Ensembl:ENSG00000144026|Vega:OTTHUMG00000130391 +84875 PARP10 MIM:609564|HGNC:HGNC:25895|Ensembl:ENSG00000178685|Vega:OTTHUMG00000165408 +84876 ORAI1 MIM:610277|HGNC:HGNC:25896 +84878 ZBTB45 HGNC:HGNC:23715|Ensembl:ENSG00000119574|Vega:OTTHUMG00000183545 +84879 MFSD2A MIM:614397|HGNC:HGNC:25897|Ensembl:ENSG00000168389|Vega:OTTHUMG00000009293 +84881 RPUSD4 HGNC:HGNC:25898|Ensembl:ENSG00000165526|Vega:OTTHUMG00000165815 +84883 AIFM2 MIM:605159|HGNC:HGNC:21411|Ensembl:ENSG00000042286|Vega:OTTHUMG00000018398 +84885 ZDHHC12 HGNC:HGNC:19159|Ensembl:ENSG00000160446|Vega:OTTHUMG00000020756 +84886 C1orf198 HGNC:HGNC:25900|Ensembl:ENSG00000119280|Vega:OTTHUMG00000037790 +84888 SPPL2A MIM:608238|HGNC:HGNC:30227|Ensembl:ENSG00000138600|Vega:OTTHUMG00000131647 +84889 SLC7A3 MIM:300443|HGNC:HGNC:11061|Ensembl:ENSG00000165349|Vega:OTTHUMG00000021780 +84890 ADO MIM:611392|HGNC:HGNC:23506|Ensembl:ENSG00000181915|Vega:OTTHUMG00000018306 +84891 ZSCAN10 HGNC:HGNC:12997|Ensembl:ENSG00000130182|Vega:OTTHUMG00000177478 +84892 POMGNT2 MIM:614828|HGNC:HGNC:25902|Ensembl:ENSG00000144647|Vega:OTTHUMG00000133038 +84893 FBXO18 MIM:607222|HGNC:HGNC:13620|Ensembl:ENSG00000134452|Vega:OTTHUMG00000017609 +84894 LINGO1 MIM:609791|HGNC:HGNC:21205|Ensembl:ENSG00000169783|Vega:OTTHUMG00000172629 +84895 MIGA2 MIM:616774|HGNC:HGNC:23621|Ensembl:ENSG00000148343|Vega:OTTHUMG00000020770 +84896 ATAD1 MIM:614452|HGNC:HGNC:25903|Ensembl:ENSG00000138138|Vega:OTTHUMG00000018685 +84897 TBRG1 MIM:610614|HGNC:HGNC:29551|Ensembl:ENSG00000154144|Vega:OTTHUMG00000153024 +84898 PLXDC2 MIM:606827|HGNC:HGNC:21013|Ensembl:ENSG00000120594|Vega:OTTHUMG00000017781 +84899 TMTC4 HGNC:HGNC:25904|Ensembl:ENSG00000125247|Vega:OTTHUMG00000017289 +84900 RNFT2 HGNC:HGNC:25905|Ensembl:ENSG00000135119|Vega:OTTHUMG00000150882 +84901 NFATC2IP MIM:614525|HGNC:HGNC:25906|Ensembl:ENSG00000176953|Vega:OTTHUMG00000097763 +84902 CEP89 MIM:615470|HGNC:HGNC:25907|Ensembl:ENSG00000121289|Vega:OTTHUMG00000180424 +84904 ARHGEF39 HGNC:HGNC:25909|Ensembl:ENSG00000137135|Vega:OTTHUMG00000019869 +84905 ZNF341 HGNC:HGNC:15992|Ensembl:ENSG00000131061|Vega:OTTHUMG00000032275 +84908 FAM136A MIM:616275|HGNC:HGNC:25911|Ensembl:ENSG00000035141|Vega:OTTHUMG00000129668 +84909 C9orf3 HGNC:HGNC:1361|Ensembl:ENSG00000148120|Vega:OTTHUMG00000020276 +84910 TMEM87B MIM:617203|HGNC:HGNC:25913|Ensembl:ENSG00000153214|Vega:OTTHUMG00000153266 +84911 ZNF382 MIM:609516|HGNC:HGNC:17409|Ensembl:ENSG00000161298|Vega:OTTHUMG00000048153 +84912 SLC35B4 MIM:610923|HGNC:HGNC:20584|Ensembl:ENSG00000205060|Vega:OTTHUMG00000155321 +84913 ATOH8 HGNC:HGNC:24126|Ensembl:ENSG00000168874|Vega:OTTHUMG00000130178 +84914 ZNF587 HGNC:HGNC:30955|Ensembl:ENSG00000198466|Vega:OTTHUMG00000154901 +84915 FAM222A HGNC:HGNC:25915|Ensembl:ENSG00000139438|Vega:OTTHUMG00000169260 +84916 UTP4 MIM:607456|HGNC:HGNC:1983|Ensembl:ENSG00000141076|Vega:OTTHUMG00000137570 +84918 LRP11 HGNC:HGNC:16936|Ensembl:ENSG00000120256|Vega:OTTHUMG00000015801 +84919 PPP1R15B MIM:613257|HGNC:HGNC:14951|Ensembl:ENSG00000158615|Vega:OTTHUMG00000036105 +84920 ALG10 MIM:603313|HGNC:HGNC:23162|Ensembl:ENSG00000139133|Vega:OTTHUMG00000169285 +84922 FIZ1 MIM:609133|HGNC:HGNC:25917|Ensembl:ENSG00000179943|Vega:OTTHUMG00000180858 +84923 FAM104A HGNC:HGNC:25918|Ensembl:ENSG00000133193|Vega:OTTHUMG00000150564 +84924 ZNF566 HGNC:HGNC:25919|Ensembl:ENSG00000186017|Vega:OTTHUMG00000048148 +84925 DIRC2 MIM:602773|HGNC:HGNC:16628|Ensembl:ENSG00000138463|Vega:OTTHUMG00000159553 +84926 SPRYD3 HGNC:HGNC:25920|Ensembl:ENSG00000167778|Vega:OTTHUMG00000170101 +84928 TMEM209 HGNC:HGNC:21898|Ensembl:ENSG00000146842|Vega:OTTHUMG00000157653 +84929 FIBCD1 MIM:613357|HGNC:HGNC:25922|Ensembl:ENSG00000130720|Vega:OTTHUMG00000020814 +84930 MASTL MIM:608221|HGNC:HGNC:19042|Ensembl:ENSG00000120539|Vega:OTTHUMG00000017855 +84931 LINC01101 HGNC:HGNC:25923|Ensembl:ENSG00000280409 +84932 RAB2B MIM:607466|HGNC:HGNC:20246|Ensembl:ENSG00000129472|Vega:OTTHUMG00000029693 +84933 C8orf76 HGNC:HGNC:25924|Ensembl:ENSG00000189376|Vega:OTTHUMG00000172562 +84934 RITA1 HGNC:HGNC:25925|Ensembl:ENSG00000139405|Vega:OTTHUMG00000169643 +84935 MEDAG HGNC:HGNC:25926|Ensembl:ENSG00000102802|Vega:OTTHUMG00000016679 +84936 ZFYVE19 HGNC:HGNC:20758|Ensembl:ENSG00000166140|Vega:OTTHUMG00000172537 +84937 ZNRF1 MIM:612060|HGNC:HGNC:18452|Ensembl:ENSG00000186187|Vega:OTTHUMG00000137606 +84938 ATG4C MIM:611339|HGNC:HGNC:16040|Ensembl:ENSG00000125703|Vega:OTTHUMG00000009142 +84939 MUM1 HGNC:HGNC:29641|Ensembl:ENSG00000160953|Vega:OTTHUMG00000180055 +84940 CORO6 HGNC:HGNC:21356|Ensembl:ENSG00000167549|Vega:OTTHUMG00000132732 +84941 HSH2D MIM:608349|HGNC:HGNC:24920|Ensembl:ENSG00000196684|Vega:OTTHUMG00000182256 +84942 WDR73 MIM:616144|HGNC:HGNC:25928|Ensembl:ENSG00000177082|Vega:OTTHUMG00000172375 +84944 MAEL MIM:611368|HGNC:HGNC:25929|Ensembl:ENSG00000143194|Vega:OTTHUMG00000034432 +84945 ABHD13 HGNC:HGNC:20293|Ensembl:ENSG00000139826|Vega:OTTHUMG00000017330 +84946 LTV1 HGNC:HGNC:21173|Ensembl:ENSG00000135521|Vega:OTTHUMG00000015733 +84947 SERAC1 MIM:614725|HGNC:HGNC:21061|Ensembl:ENSG00000122335|Vega:OTTHUMG00000015905 +84948 TIGD5 HGNC:HGNC:18336|Ensembl:ENSG00000179886|Vega:OTTHUMG00000162260 +84950 PRPF38A MIM:617031|HGNC:HGNC:25930|Ensembl:ENSG00000134748|Vega:OTTHUMG00000008199 +84951 TNS4 MIM:608385|HGNC:HGNC:24352|Ensembl:ENSG00000131746|Vega:OTTHUMG00000133330 +84952 CGNL1 MIM:607856|HGNC:HGNC:25931|Ensembl:ENSG00000128849|Vega:OTTHUMG00000166485 +84953 MICALCL MIM:612355|HGNC:HGNC:25933|Ensembl:ENSG00000133808|Vega:OTTHUMG00000165777 +84954 MPND HGNC:HGNC:25934|Ensembl:ENSG00000008382|Vega:OTTHUMG00000181914 +84955 NUDCD1 MIM:606109|HGNC:HGNC:24306|Ensembl:ENSG00000120526|Vega:OTTHUMG00000164931 +84957 RELT MIM:611211|HGNC:HGNC:13764|Ensembl:ENSG00000054967|Vega:OTTHUMG00000167973 +84958 SYTL1 MIM:608042|HGNC:HGNC:15584|Ensembl:ENSG00000142765|Vega:OTTHUMG00000005770 +84959 UBASH3B MIM:609201|HGNC:HGNC:29884|Ensembl:ENSG00000154127|Vega:OTTHUMG00000166025 +84960 CCDC183 MIM:615955|HGNC:HGNC:28236|Ensembl:ENSG00000213213|Vega:OTTHUMG00000159445 +84961 FBXL20 MIM:609086|HGNC:HGNC:24679|Ensembl:ENSG00000108306|Vega:OTTHUMG00000179002 +84962 AJUBA MIM:609066|HGNC:HGNC:20250|Ensembl:ENSG00000129474|Vega:OTTHUMG00000028711 +84964 ALKBH6 MIM:613304|HGNC:HGNC:28243|Ensembl:ENSG00000239382|Vega:OTTHUMG00000048137 +84966 IGSF21 HGNC:HGNC:28246|Ensembl:ENSG00000117154|Vega:OTTHUMG00000002432 +84967 LSM10 HGNC:HGNC:17562|Ensembl:ENSG00000181817|Vega:OTTHUMG00000008140 +84968 PNMA6A MIM:300917|HGNC:HGNC:28248|Ensembl:ENSG00000235961|Vega:OTTHUMG00000186485 +84969 TOX2 MIM:611163|HGNC:HGNC:16095|Ensembl:ENSG00000124191|Vega:OTTHUMG00000032517 +84970 C1orf94 HGNC:HGNC:28250|Ensembl:ENSG00000142698|Vega:OTTHUMG00000004012 +84971 ATG4D MIM:611340|HGNC:HGNC:20789|Ensembl:ENSG00000130734|Vega:OTTHUMG00000180582 +84973 SNHG7 HGNC:HGNC:28254|Ensembl:ENSG00000233016 +84975 MFSD5 HGNC:HGNC:28156|Ensembl:ENSG00000182544|Vega:OTTHUMG00000170028 +84976 DISP1 MIM:607502|HGNC:HGNC:19711|Ensembl:ENSG00000154309|Vega:OTTHUMG00000037893 +84978 FRMD5 MIM:616309|HGNC:HGNC:28214|Ensembl:ENSG00000171877|Vega:OTTHUMG00000060475 +84981 MIR22HG HGNC:HGNC:28219|Ensembl:ENSG00000186594 +84983 FAM222A-AS1 HGNC:HGNC:28223|Ensembl:ENSG00000255650 +84984 CEP19 MIM:615586|HGNC:HGNC:28209|Ensembl:ENSG00000174007|Vega:OTTHUMG00000153933 +84985 FAM83A HGNC:HGNC:28210|Ensembl:ENSG00000147689|Vega:OTTHUMG00000165083 +84986 ARHGAP19 MIM:611587|HGNC:HGNC:23724|Ensembl:ENSG00000213390|Vega:OTTHUMG00000018845 +84987 COX14 MIM:614478|HGNC:HGNC:28216|Ensembl:ENSG00000178449|Vega:OTTHUMG00000185635 +84988 PPP1R16A MIM:609172|HGNC:HGNC:14941|Ensembl:ENSG00000160972|Vega:OTTHUMG00000165173 +84989 JMJD1C-AS1 HGNC:HGNC:28222|Ensembl:ENSG00000272767 +84991 RBM17 MIM:606935|HGNC:HGNC:16944|Ensembl:ENSG00000134453|Vega:OTTHUMG00000017618 +84992 PIGY MIM:610662|HGNC:HGNC:28213|Ensembl:ENSG00000255072|Vega:OTTHUMG00000166563 +84993 UBL7 MIM:609748|HGNC:HGNC:28221|Ensembl:ENSG00000138629|Vega:OTTHUMG00000139001 +84996 URB1-AS1 HGNC:HGNC:23128|Ensembl:ENSG00000256073 +85001 MGC16275 Ensembl:ENSG00000246731 +85002 FAM86B1 MIM:616122|HGNC:HGNC:28268|Ensembl:ENSG00000186523|Vega:OTTHUMG00000165298 +85003 BFSP2-AS1 HGNC:HGNC:28425|Ensembl:ENSG00000249993 +85004 RERG MIM:612664|HGNC:HGNC:15980|Ensembl:ENSG00000134533|Vega:OTTHUMG00000168745 +85007 PHYKPL MIM:614683|HGNC:HGNC:28249|Ensembl:ENSG00000175309|Vega:OTTHUMG00000130892 +85009 MGC16025 - +85012 TCEAL3 HGNC:HGNC:28247|Ensembl:ENSG00000196507|Vega:OTTHUMG00000022106 +85013 TMEM128 HGNC:HGNC:28201|Ensembl:ENSG00000132406|Vega:OTTHUMG00000125475 +85014 TMEM141 HGNC:HGNC:28211|Ensembl:ENSG00000244187|Vega:OTTHUMG00000020945 +85015 USP45 HGNC:HGNC:20080|Ensembl:ENSG00000123552|Vega:OTTHUMG00000015267 +85016 C11orf70 HGNC:HGNC:28188|Ensembl:ENSG00000137691|Vega:OTTHUMG00000167320 +85019 TMEM241 MIM:615430|HGNC:HGNC:31723|Ensembl:ENSG00000134490|Vega:OTTHUMG00000131771 +85021 REPS1 MIM:614825|HGNC:HGNC:15578|Ensembl:ENSG00000135597|Vega:OTTHUMG00000015685 +85025 TMEM60 HGNC:HGNC:21754|Ensembl:ENSG00000135211|Vega:OTTHUMG00000130689 +85026 ARRDC1-AS1 HGNC:HGNC:23395|Ensembl:ENSG00000203993 +85027 SMIM3 MIM:608324|HGNC:HGNC:30248|Ensembl:ENSG00000256235|Vega:OTTHUMG00000163646 +85028 SNHG12 HGNC:HGNC:30062|Ensembl:ENSG00000197989 +85235 HIST1H2AH MIM:615013|HGNC:HGNC:13671|Ensembl:ENSG00000274997|Vega:OTTHUMG00000014468 +85236 HIST1H2BK MIM:615045|HGNC:HGNC:13954|Ensembl:ENSG00000197903|Vega:OTTHUMG00000014473 +85280 KRTAP9-4 HGNC:HGNC:18902|Ensembl:ENSG00000241595|Vega:OTTHUMG00000133438 +85285 KRTAP4-1 HGNC:HGNC:18907 +85289 KRTAP4-5 HGNC:HGNC:18899|Ensembl:ENSG00000198271|Vega:OTTHUMG00000133638 +85290 KRTAP4-3 HGNC:HGNC:18908|Ensembl:ENSG00000196156|Vega:OTTHUMG00000133639 +85291 KRTAP4-2 HGNC:HGNC:18900|Ensembl:ENSG00000244537|Vega:OTTHUMG00000133437 +85293 KRTAP3-3 HGNC:HGNC:18890|Ensembl:ENSG00000212899|Vega:OTTHUMG00000133591 +85294 KRTAP2-4 HGNC:HGNC:18891|Ensembl:ENSG00000213417|Vega:OTTHUMG00000133594 +85300 ATCAY MIM:608179|HGNC:HGNC:779|Ensembl:ENSG00000167654|Vega:OTTHUMG00000181836 +85301 COL27A1 MIM:608461|HGNC:HGNC:22986|Ensembl:ENSG00000196739|Vega:OTTHUMG00000020537 +85302 FBF1 MIM:616807|HGNC:HGNC:24674|Ensembl:ENSG00000188878|Vega:OTTHUMG00000179919 +85303 HIST1H2APS2 HGNC:HGNC:18804 +85313 PPIL4 MIM:607609|HGNC:HGNC:15702|Ensembl:ENSG00000131013|Vega:OTTHUMG00000015788 +85314 ERVE-1 MIM:606601|HGNC:HGNC:14602 +85315 PAQR8 MIM:607780|HGNC:HGNC:15708|Ensembl:ENSG00000170915|Vega:OTTHUMG00000014846 +85316 BAGE5 HGNC:HGNC:15732 +85317 BAGE4 HGNC:HGNC:15730 +85318 BAGE3 HGNC:HGNC:15728 +85319 BAGE2 HGNC:HGNC:15723 +85320 ABCC11 MIM:607040|HGNC:HGNC:14639|Ensembl:ENSG00000121270|Vega:OTTHUMG00000133146 +85329 LGALS12 MIM:606096|HGNC:HGNC:15788|Ensembl:ENSG00000133317|Vega:OTTHUMG00000167807 +85340 KRT90P HGNC:HGNC:30195 +85343 KRTAP2-5P HGNC:HGNC:18920 +85344 KRT89P HGNC:HGNC:30196 +85345 KRTAP3-4P HGNC:HGNC:18919 +85347 KRTAP9-11P HGNC:HGNC:18918 +85348 KRT88P HGNC:HGNC:30197 +85349 KRT87P HGNC:HGNC:30198 +85352 KIAA1644 HGNC:HGNC:29335|Ensembl:ENSG00000138944|Vega:OTTHUMG00000030991 +85354 KRTAP4-16 HGNC:HGNC:18921 +85358 SHANK3 MIM:606230|HGNC:HGNC:14294|Ensembl:ENSG00000251322 +85359 DGCR6L MIM:609459|HGNC:HGNC:18551|Ensembl:ENSG00000128185|Vega:OTTHUMG00000150583 +85360 SYDE1 MIM:617377|HGNC:HGNC:25824|Ensembl:ENSG00000105137|Vega:OTTHUMG00000183207 +85363 TRIM5 MIM:608487|HGNC:HGNC:16276|Ensembl:ENSG00000132256|Vega:OTTHUMG00000066893 +85364 ZCCHC3 HGNC:HGNC:16230|Ensembl:ENSG00000247315|Vega:OTTHUMG00000188280 +85365 ALG2 MIM:607905|HGNC:HGNC:23159|Ensembl:ENSG00000119523|Vega:OTTHUMG00000020355 +85366 MYLK2 MIM:606566|HGNC:HGNC:16243|Ensembl:ENSG00000101306|Vega:OTTHUMG00000032194 +85369 STRIP1 HGNC:HGNC:25916|Ensembl:ENSG00000143093|Vega:OTTHUMG00000170607 +85371 KIAA1656 - +85376 RIMBP3 MIM:612699|HGNC:HGNC:29344|Ensembl:ENSG00000275793|Vega:OTTHUMG00000188355 +85377 MICALL1 HGNC:HGNC:29804|Ensembl:ENSG00000100139|Vega:OTTHUMG00000150670 +85378 TUBGCP6 MIM:610053|HGNC:HGNC:18127|Ensembl:ENSG00000128159|Vega:OTTHUMG00000030150 +85379 KIAA1671 HGNC:HGNC:29345|Ensembl:ENSG00000197077|Vega:OTTHUMG00000150841 +85388 SNORD14B HGNC:HGNC:31803|Ensembl:ENSG00000201403 +85389 SNORD14C HGNC:HGNC:30352|Ensembl:ENSG00000202252 +85390 SNORD14D HGNC:HGNC:30353|Ensembl:ENSG00000207118 +85391 SNORD14E HGNC:HGNC:30354|Ensembl:ENSG00000200879 +85395 FAM207A HGNC:HGNC:15811|Ensembl:ENSG00000160256|Vega:OTTHUMG00000090293 +85397 RGS8 MIM:607189|HGNC:HGNC:16810|Ensembl:ENSG00000135824|Vega:OTTHUMG00000035219 +85403 EAF1 MIM:608315|HGNC:HGNC:20907|Ensembl:ENSG00000144597|Vega:OTTHUMG00000162544 +85406 DNAJC14 MIM:606092|HGNC:HGNC:24581|Ensembl:ENSG00000135392|Vega:OTTHUMG00000170427 +85407 NKD1 MIM:607851|HGNC:HGNC:17045|Ensembl:ENSG00000140807|Vega:OTTHUMG00000133169 +85409 NKD2 MIM:607852|HGNC:HGNC:17046|Ensembl:ENSG00000145506|Vega:OTTHUMG00000090348 +85413 SLC22A16 MIM:608276|HGNC:HGNC:20302|Ensembl:ENSG00000004809|Vega:OTTHUMG00000016171 +85414 SLC45A3 MIM:605097|HGNC:HGNC:8642|Ensembl:ENSG00000158715|Vega:OTTHUMG00000037223 +85415 RHPN2 HGNC:HGNC:19974|Ensembl:ENSG00000131941|Vega:OTTHUMG00000180340 +85416 ZIC5 HGNC:HGNC:20322|Ensembl:ENSG00000139800|Vega:OTTHUMG00000017280 +85417 CCNB3 MIM:300456|HGNC:HGNC:18709|Ensembl:ENSG00000147082|Vega:OTTHUMG00000021519 +85437 ZCRB1 MIM:610750|HGNC:HGNC:29620|Ensembl:ENSG00000139168|Vega:OTTHUMG00000169382 +85438 CABS1 HGNC:HGNC:30710|Ensembl:ENSG00000145309|Vega:OTTHUMG00000129405 +85439 STON2 MIM:608467|HGNC:HGNC:30652|Ensembl:ENSG00000140022|Vega:OTTHUMG00000171416 +85440 DOCK7 MIM:615730|HGNC:HGNC:19190|Ensembl:ENSG00000116641|Vega:OTTHUMG00000013131 +85441 HELZ2 MIM:611265|HGNC:HGNC:30021|Ensembl:ENSG00000130589|Vega:OTTHUMG00000032969 +85442 KNDC1 MIM:616237|HGNC:HGNC:29374|Ensembl:ENSG00000171798|Vega:OTTHUMG00000019303 +85443 DCLK3 MIM:613167|HGNC:HGNC:19005|Ensembl:ENSG00000163673|Vega:OTTHUMG00000155805 +85444 LRRCC1 HGNC:HGNC:29373|Ensembl:ENSG00000133739|Vega:OTTHUMG00000164784 +85445 CNTNAP4 MIM:610518|HGNC:HGNC:18747|Ensembl:ENSG00000152910|Vega:OTTHUMG00000137617 +85446 ZFHX2 HGNC:HGNC:20152|Ensembl:ENSG00000136367|Vega:OTTHUMG00000156894 +85449 KIAA1755 HGNC:HGNC:29372|Ensembl:ENSG00000149633|Vega:OTTHUMG00000032436 +85450 ITPRIP HGNC:HGNC:29370|Ensembl:ENSG00000148841|Vega:OTTHUMG00000184003 +85451 UNK MIM:616375|HGNC:HGNC:29369|Ensembl:ENSG00000132478|Vega:OTTHUMG00000179892 +85452 CFAP74 HGNC:HGNC:29368|Ensembl:ENSG00000142609|Vega:OTTHUMG00000000945 +85453 TSPYL5 MIM:614721|HGNC:HGNC:29367|Ensembl:ENSG00000180543|Vega:OTTHUMG00000164857 +85455 DISP2 MIM:607503|HGNC:HGNC:19712|Ensembl:ENSG00000140323|Vega:OTTHUMG00000129983 +85456 TNKS1BP1 MIM:607104|HGNC:HGNC:19081|Ensembl:ENSG00000149115|Vega:OTTHUMG00000167022 +85457 CIPC MIM:616995|HGNC:HGNC:20365|Ensembl:ENSG00000198894|Vega:OTTHUMG00000171573 +85458 DIXDC1 MIM:610493|HGNC:HGNC:23695|Ensembl:ENSG00000150764|Vega:OTTHUMG00000166912 +85459 CEP295 HGNC:HGNC:29366|Ensembl:ENSG00000166004|Vega:OTTHUMG00000167449 +85460 ZNF518B HGNC:HGNC:29365|Ensembl:ENSG00000178163|Vega:OTTHUMG00000160060 +85461 TANC1 MIM:611397|HGNC:HGNC:29364|Ensembl:ENSG00000115183|Vega:OTTHUMG00000153945 +85462 FHDC1 HGNC:HGNC:29363|Ensembl:ENSG00000137460|Vega:OTTHUMG00000161452 +85463 ZC3H12C MIM:615001|HGNC:HGNC:29362|Ensembl:ENSG00000149289|Vega:OTTHUMG00000166572 +85464 SSH2 MIM:606779|HGNC:HGNC:30580|Ensembl:ENSG00000141298|Vega:OTTHUMG00000132752 +85465 SELENOI MIM:607915|HGNC:HGNC:29361|Ensembl:ENSG00000138018|Vega:OTTHUMG00000151931 +85474 LBX2 MIM:607164|HGNC:HGNC:15525|Ensembl:ENSG00000179528|Vega:OTTHUMG00000170595 +85476 GFM1 MIM:606639|HGNC:HGNC:13780|Ensembl:ENSG00000168827|Vega:OTTHUMG00000158804 +85477 SCIN MIM:613416|HGNC:HGNC:21695|Ensembl:ENSG00000006747|Vega:OTTHUMG00000152385 +85478 CCDC65 MIM:611088|HGNC:HGNC:29937|Ensembl:ENSG00000139537|Vega:OTTHUMG00000170401 +85479 DNAJC5B MIM:613945|HGNC:HGNC:24138|Ensembl:ENSG00000147570|Vega:OTTHUMG00000164470 +85480 TSLP MIM:607003|HGNC:HGNC:30743|Ensembl:ENSG00000145777|Vega:OTTHUMG00000128791 +85481 PSKH2 HGNC:HGNC:18997|Ensembl:ENSG00000147613|Vega:OTTHUMG00000163638 +85486 RPS19P1 HGNC:HGNC:16534 +85487 RPS19P2 HGNC:HGNC:17047 +85495 RPPH1 MIM:608513|HGNC:HGNC:19273|Ensembl:ENSG00000277209 +85502 SCAR3 MIM:271250|HGNC:HGNC:32976 +85503 MCOPCB1 MIM:300345 +85504 BDET MIM:605913 +85505 ACRPS MIM:605967 +85507 DFNA18 MIM:606012|HGNC:HGNC:13268 +85508 SCRT2 HGNC:HGNC:15952|Ensembl:ENSG00000215397|Vega:OTTHUMG00000130829 +85509 MBD3L1 MIM:607963|HGNC:HGNC:15774|Ensembl:ENSG00000170948|Vega:OTTHUMG00000182198 +85569 GALP MIM:611178|HGNC:HGNC:24840|Ensembl:ENSG00000197487|Vega:OTTHUMG00000181826 +85824 RPL12P12 HGNC:HGNC:15951 +85865 GTPBP10 MIM:610920|HGNC:HGNC:25106|Ensembl:ENSG00000105793|Vega:OTTHUMG00000023655 +86123 YWHAZP5 HGNC:HGNC:30564 +86614 HSFY1 MIM:400029|HGNC:HGNC:18568|Ensembl:ENSG00000172468|Vega:OTTHUMG00000041980 +86781 RPS2P7 HGNC:HGNC:15838 +87171 ARPC3P1 HGNC:HGNC:16092 +87178 PNPT1 MIM:610316|HGNC:HGNC:23166|Ensembl:ENSG00000138035|Vega:OTTHUMG00000129335 +87688 RPL7AP50 HGNC:HGNC:36117 +87769 GGACT MIM:613378|HGNC:HGNC:25100|Ensembl:ENSG00000134864|Vega:OTTHUMG00000017291 +88455 ANKRD13A MIM:615123|HGNC:HGNC:21268|Ensembl:ENSG00000076513|Vega:OTTHUMG00000169314 +88745 RRP36 MIM:613475|HGNC:HGNC:21374|Ensembl:ENSG00000124541|Vega:OTTHUMG00000014715 +89122 TRIM4 HGNC:HGNC:16275|Ensembl:ENSG00000146833|Vega:OTTHUMG00000156648 +89758 LINC01621 HGNC:HGNC:14109 +89760 MRX75 HGNC:HGNC:7309 +89761 NUFIP1P HGNC:HGNC:8058 +89765 RSPH1 MIM:609314|HGNC:HGNC:12371|Ensembl:ENSG00000160188|Vega:OTTHUMG00000086804 +89766 UMODL1 MIM:613859|HGNC:HGNC:12560|Ensembl:ENSG00000177398|Vega:OTTHUMG00000086788 +89770 IGHV3-30-5 HGNC:HGNC:5594|IMGT/GENE-DB:IGHV3-30-5 +89777 SERPINB12 MIM:615662|HGNC:HGNC:14220|Ensembl:ENSG00000166634|Vega:OTTHUMG00000132789 +89778 SERPINB11 MIM:615682|HGNC:HGNC:14221|Ensembl:ENSG00000206072|Vega:OTTHUMG00000060404 +89780 WNT3A MIM:606359|HGNC:HGNC:15983|Ensembl:ENSG00000154342|Vega:OTTHUMG00000037593 +89781 HPS4 MIM:606682|HGNC:HGNC:15844|Ensembl:ENSG00000100099|Vega:OTTHUMG00000030459 +89782 LMLN MIM:609380|HGNC:HGNC:15991|Ensembl:ENSG00000185621|Vega:OTTHUMG00000155375 +89790 SIGLEC10 MIM:606091|HGNC:HGNC:15620|Ensembl:ENSG00000142512|Vega:OTTHUMG00000165521 +89792 GAL3ST3 MIM:608234|HGNC:HGNC:24144|Ensembl:ENSG00000175229|Vega:OTTHUMG00000166667 +89795 NAV3 MIM:611629|HGNC:HGNC:15998|Ensembl:ENSG00000067798|Vega:OTTHUMG00000170001 +89796 NAV1 MIM:611628|HGNC:HGNC:15989|Ensembl:ENSG00000134369|Vega:OTTHUMG00000035766 +89797 NAV2 MIM:607026|HGNC:HGNC:15997|Ensembl:ENSG00000166833|Vega:OTTHUMG00000151837 +89801 PPP1R3F HGNC:HGNC:14944|Ensembl:ENSG00000049769|Vega:OTTHUMG00000024139 +89822 KCNK17 MIM:607370|HGNC:HGNC:14465|Ensembl:ENSG00000124780|Vega:OTTHUMG00000014646 +89832 CHRFAM7A MIM:609756|HGNC:HGNC:15781|Ensembl:ENSG00000166664|Vega:OTTHUMG00000175645 +89837 ULK4P3 HGNC:HGNC:15777|Ensembl:ENSG00000178081 +89838 ULK4P1 HGNC:HGNC:15775|Ensembl:ENSG00000261279 +89839 ARHGAP11B MIM:616310|HGNC:HGNC:15782|Ensembl:ENSG00000187951|Vega:OTTHUMG00000175656 +89844 LOC89844 - +89845 ABCC10 MIM:612509|HGNC:HGNC:52|Ensembl:ENSG00000124574|Vega:OTTHUMG00000014733 +89846 FGD3 MIM:617554|HGNC:HGNC:16027|Ensembl:ENSG00000127084|Vega:OTTHUMG00000021032 +89848 FCHSD1 MIM:617555|HGNC:HGNC:25463|Ensembl:ENSG00000197948|Vega:OTTHUMG00000163762 +89849 ATG16L2 HGNC:HGNC:25464|Ensembl:ENSG00000168010|Vega:OTTHUMG00000167961 +89853 MVB12B HGNC:HGNC:23368|Ensembl:ENSG00000196814|Vega:OTTHUMG00000020687 +89857 KLHL6 MIM:614214|HGNC:HGNC:18653|Ensembl:ENSG00000172578|Vega:OTTHUMG00000148673 +89858 SIGLEC12 MIM:606094|HGNC:HGNC:15482|Ensembl:ENSG00000254521|Vega:OTTHUMG00000165524 +89866 SEC16B MIM:612855|HGNC:HGNC:30301|Ensembl:ENSG00000120341|Vega:OTTHUMG00000167206 +89869 PLCZ1 MIM:608075|HGNC:HGNC:19218|Ensembl:ENSG00000139151|Vega:OTTHUMG00000168937 +89870 TRIM15 HGNC:HGNC:16284|Ensembl:ENSG00000204610|Vega:OTTHUMG00000031031 +89872 AQP10 MIM:606578|HGNC:HGNC:16029|Ensembl:ENSG00000143595|Vega:OTTHUMG00000035980 +89873 PPH2 HGNC:HGNC:15733 +89874 SLC25A21 MIM:607571|HGNC:HGNC:14411|Ensembl:ENSG00000183032|Vega:OTTHUMG00000140250 +89876 MAATS1 MIM:609910|HGNC:HGNC:24010|Ensembl:ENSG00000183833|Vega:OTTHUMG00000159422 +89882 TPD52L3 MIM:617567|HGNC:HGNC:23382|Ensembl:ENSG00000170777|Vega:OTTHUMG00000019518 +89883 OR6W1P HGNC:HGNC:15091 +89884 LHX4 MIM:602146|HGNC:HGNC:21734|Ensembl:ENSG00000121454|Vega:OTTHUMG00000035115 +89885 FATE1 MIM:300450|HGNC:HGNC:24683|Ensembl:ENSG00000147378|Vega:OTTHUMG00000024172 +89886 SLAMF9 MIM:608589|HGNC:HGNC:18430|Ensembl:ENSG00000162723|Vega:OTTHUMG00000024074 +89887 ZNF628 MIM:610671|HGNC:HGNC:28054|Ensembl:ENSG00000197483|Vega:OTTHUMG00000150396 +89890 KBTBD6 HGNC:HGNC:25340|Ensembl:ENSG00000165572|Vega:OTTHUMG00000016786 +89891 WDR34 MIM:613363|HGNC:HGNC:28296|Ensembl:ENSG00000119333|Vega:OTTHUMG00000020750 +89894 TMEM116 HGNC:HGNC:25084|Ensembl:ENSG00000198270|Vega:OTTHUMG00000169606 +89910 UBE3B MIM:608047|HGNC:HGNC:13478|Ensembl:ENSG00000151148|Vega:OTTHUMG00000169254 +89927 C16orf45 HGNC:HGNC:19213|Ensembl:ENSG00000166780|Vega:OTTHUMG00000129883 +89932 PAPLN HGNC:HGNC:19262|Ensembl:ENSG00000100767|Vega:OTTHUMG00000171366 +89941 RHOT2 MIM:613889|HGNC:HGNC:21169|Ensembl:ENSG00000140983|Vega:OTTHUMG00000121139 +89944 GLB1L2 HGNC:HGNC:25129|Ensembl:ENSG00000149328|Vega:OTTHUMG00000167179 +89953 KLC4 HGNC:HGNC:21624|Ensembl:ENSG00000137171|Vega:OTTHUMG00000014720 +89958 SAPCD2 MIM:612057|HGNC:HGNC:28055|Ensembl:ENSG00000186193|Vega:OTTHUMG00000020961 +89970 RSPRY1 MIM:616585|HGNC:HGNC:29420|Ensembl:ENSG00000159579|Vega:OTTHUMG00000133462 +89978 DPH6 HGNC:HGNC:30543|Ensembl:ENSG00000134146|Vega:OTTHUMG00000129759 +90007 MIDN MIM:606700|HGNC:HGNC:16298|Ensembl:ENSG00000167470|Vega:OTTHUMG00000180144 +90011 KIR3DX1 HGNC:HGNC:25043|Ensembl:ENSG00000104970|Vega:OTTHUMG00000065696 +90019 SYT8 MIM:607719|HGNC:HGNC:19264|Ensembl:ENSG00000149043|Vega:OTTHUMG00000009026 +90024 FLJ20021 Ensembl:ENSG00000254531 +90025 UBE3D MIM:612495|HGNC:HGNC:21381|Ensembl:ENSG00000118420|Vega:OTTHUMG00000015108 +90050 FAM181A HGNC:HGNC:20491|Ensembl:ENSG00000140067|Vega:OTTHUMG00000171297 +90060 CCDC120 MIM:300947|HGNC:HGNC:28910|Ensembl:ENSG00000147144|Vega:OTTHUMG00000021509 +90070 LACRT MIM:607360|HGNC:HGNC:16430|Ensembl:ENSG00000135413|Vega:OTTHUMG00000169936 +90075 ZNF30 HGNC:HGNC:13090|Ensembl:ENSG00000168661|Vega:OTTHUMG00000182960 +90102 PHLDB2 MIM:610298|HGNC:HGNC:29573|Ensembl:ENSG00000144824|Vega:OTTHUMG00000159282 +90113 VWA5B2 HGNC:HGNC:25144|Ensembl:ENSG00000145198|Vega:OTTHUMG00000156820 +90120 TMEM250 HGNC:HGNC:31009|Ensembl:ENSG00000238227|Vega:OTTHUMG00000020922 +90121 TSR2 MIM:300945|HGNC:HGNC:25455|Ensembl:ENSG00000158526|Vega:OTTHUMG00000021628 +90133 KRT8P12 HGNC:HGNC:28057 +90134 KCNH7 MIM:608169|HGNC:HGNC:18863|Ensembl:ENSG00000184611|Vega:OTTHUMG00000132069 +90135 BTBD6 HGNC:HGNC:19897|Ensembl:ENSG00000184887|Vega:OTTHUMG00000029887 +90139 TSPAN18 HGNC:HGNC:20660|Ensembl:ENSG00000157570|Vega:OTTHUMG00000163883 +90141 EFCAB11 HGNC:HGNC:20357|Ensembl:ENSG00000140025|Vega:OTTHUMG00000148671 +90161 HS6ST2 MIM:300545|HGNC:HGNC:19133|Ensembl:ENSG00000171004|Vega:OTTHUMG00000022430 +90167 FRMD7 MIM:300628|HGNC:HGNC:8079|Ensembl:ENSG00000165694|Vega:OTTHUMG00000022421 +90187 EMILIN3 MIM:608929|HGNC:HGNC:16123|Ensembl:ENSG00000183798|Vega:OTTHUMG00000046304 +90193 RPL7P6 HGNC:HGNC:32430 +90196 SYS1 MIM:612979|HGNC:HGNC:16162|Ensembl:ENSG00000204070|Vega:OTTHUMG00000032579 +90199 WFDC8 HGNC:HGNC:16163|Ensembl:ENSG00000158901|Vega:OTTHUMG00000046342 +90203 SNX21 HGNC:HGNC:16154|Ensembl:ENSG00000124104|Vega:OTTHUMG00000032624 +90204 ZSWIM1 HGNC:HGNC:16155|Ensembl:ENSG00000168612|Vega:OTTHUMG00000074023 +90226 UCN2 MIM:605902|HGNC:HGNC:18414|Ensembl:ENSG00000145040|Vega:OTTHUMG00000133533 +90231 KIAA2013 HGNC:HGNC:28513|Ensembl:ENSG00000116685|Vega:OTTHUMG00000002391 +90233 ZNF551 HGNC:HGNC:25108|Ensembl:ENSG00000204519|Vega:OTTHUMG00000183470 +90246 LOC90246 - +90249 UNC5A MIM:607869|HGNC:HGNC:12567|Ensembl:ENSG00000113763|Vega:OTTHUMG00000163225 +90268 OTULIN MIM:615712|HGNC:HGNC:25118|Ensembl:ENSG00000154124|Vega:OTTHUMG00000161762 +90271 OLMALINC MIM:616240|HGNC:HGNC:28060 +90273 CEACAM21 HGNC:HGNC:28834|Ensembl:ENSG00000007129|Vega:OTTHUMG00000151062 +90288 EFCAB12 HGNC:HGNC:28061|Ensembl:ENSG00000172771|Vega:OTTHUMG00000159464 +90293 KLHL13 MIM:300655|HGNC:HGNC:22931|Ensembl:ENSG00000003096|Vega:OTTHUMG00000022252 +90313 TP53I13 HGNC:HGNC:25102|Ensembl:ENSG00000167543|Vega:OTTHUMG00000179723 +90316 TGIF2LX MIM:300411|HGNC:HGNC:18570|Ensembl:ENSG00000153779|Vega:OTTHUMG00000021954 +90317 ZNF616 HGNC:HGNC:28062|Ensembl:ENSG00000204611|Vega:OTTHUMG00000182566 +90321 ZNF766 HGNC:HGNC:28063|Ensembl:ENSG00000196214|Vega:OTTHUMG00000182629 +90324 CCDC97 HGNC:HGNC:28289|Ensembl:ENSG00000142039|Vega:OTTHUMG00000182722 +90326 THAP3 MIM:612532|HGNC:HGNC:20855|Ensembl:ENSG00000041988|Vega:OTTHUMG00000001440 +90332 EXOC3L2 MIM:616927|HGNC:HGNC:30162|Ensembl:ENSG00000283632 +90333 ZNF468 MIM:616841|HGNC:HGNC:33105|Ensembl:ENSG00000204604|Vega:OTTHUMG00000182687 +90338 ZNF160 MIM:600398|HGNC:HGNC:12948|Ensembl:ENSG00000170949|Vega:OTTHUMG00000182854 +90342 FER1L5 HGNC:HGNC:19044|Ensembl:ENSG00000249715|Vega:OTTHUMG00000154929 +90352 MAGOH3P HGNC:HGNC:20020 +90353 CTU1 MIM:612694|HGNC:HGNC:29590|Ensembl:ENSG00000142544|Vega:OTTHUMG00000182910 +90355 C5orf30 MIM:616608|HGNC:HGNC:25052|Ensembl:ENSG00000181751|Vega:OTTHUMG00000128738 +90362 FAM110B MIM:611394|HGNC:HGNC:28587|Ensembl:ENSG00000169122|Vega:OTTHUMG00000164282 +90378 SAMD1 HGNC:HGNC:17958|Ensembl:ENSG00000141858|Vega:OTTHUMG00000166628 +90379 DCAF15 HGNC:HGNC:25095|Ensembl:ENSG00000132017|Vega:OTTHUMG00000181882 +90381 TICRR MIM:613298|HGNC:HGNC:28704|Ensembl:ENSG00000140534|Vega:OTTHUMG00000149648 +90390 MED30 MIM:610237|HGNC:HGNC:23032|Ensembl:ENSG00000164758|Vega:OTTHUMG00000164920 +90407 TMEM41A HGNC:HGNC:30544|Ensembl:ENSG00000163900|Vega:OTTHUMG00000156660 +90410 IFT20 MIM:614394|HGNC:HGNC:30989|Ensembl:ENSG00000109083|Vega:OTTHUMG00000179412 +90411 MCFD2 MIM:607788|HGNC:HGNC:18451|Ensembl:ENSG00000180398|Vega:OTTHUMG00000153100 +90416 CCDC32 HGNC:HGNC:28295|Ensembl:ENSG00000128891|Vega:OTTHUMG00000129993 +90417 KNSTRN MIM:614718|HGNC:HGNC:30767|Ensembl:ENSG00000128944|Vega:OTTHUMG00000172454 +90423 ATP6V1E2 MIM:617385|HGNC:HGNC:18125|Ensembl:ENSG00000250565|Vega:OTTHUMG00000128819 +90427 BMF MIM:606266|HGNC:HGNC:24132|Ensembl:ENSG00000104081|Vega:OTTHUMG00000129875 +90441 ZNF622 MIM:608694|HGNC:HGNC:30958|Ensembl:ENSG00000173545|Vega:OTTHUMG00000090567 +90459 ERI1 MIM:608739|HGNC:HGNC:23994|Ensembl:ENSG00000104626|Vega:OTTHUMG00000129328 +90480 GADD45GIP1 MIM:605162|HGNC:HGNC:29996|Ensembl:ENSG00000179271|Vega:OTTHUMG00000180724 +90485 ZNF835 HGNC:HGNC:34332|Ensembl:ENSG00000127903|Vega:OTTHUMG00000182158 +90488 TMEM263 HGNC:HGNC:28281|Ensembl:ENSG00000151135|Vega:OTTHUMG00000170014 +90499 FAM95A HGNC:HGNC:28069 +90506 LRRC46 HGNC:HGNC:25047|Ensembl:ENSG00000141294|Vega:OTTHUMG00000178289 +90507 SCRN2 MIM:614966|HGNC:HGNC:30381|Ensembl:ENSG00000141295|Vega:OTTHUMG00000178290 +90522 YIF1B HGNC:HGNC:30511|Ensembl:ENSG00000167645|Vega:OTTHUMG00000182324 +90523 MLIP MIM:614106|HGNC:HGNC:21355|Ensembl:ENSG00000146147|Vega:OTTHUMG00000014891 +90525 SHF MIM:617313|HGNC:HGNC:25116|Ensembl:ENSG00000138606|Vega:OTTHUMG00000131353 +90527 DUOXA1 MIM:612771|HGNC:HGNC:26507|Ensembl:ENSG00000140254|Vega:OTTHUMG00000131352 +90529 STPG1 MIM:615826|HGNC:HGNC:28070|Ensembl:ENSG00000001460|Vega:OTTHUMG00000003297 +90550 MCU MIM:614197|HGNC:HGNC:23526|Ensembl:ENSG00000156026|Vega:OTTHUMG00000018443 +90557 CCDC74A HGNC:HGNC:25197|Ensembl:ENSG00000163040|Vega:OTTHUMG00000131667 +90576 ZNF799 HGNC:HGNC:28071|Ensembl:ENSG00000196466|Vega:OTTHUMG00000156408 +90580 TIMM29 MIM:617380|HGNC:HGNC:25152|Ensembl:ENSG00000142444|Vega:OTTHUMG00000180700 +90586 AOC4P HGNC:HGNC:48869|Ensembl:ENSG00000260105 +90589 ZNF625 HGNC:HGNC:30571|Ensembl:ENSG00000257591|Vega:OTTHUMG00000156407 +90592 ZNF700 HGNC:HGNC:25292|Ensembl:ENSG00000196757|Vega:OTTHUMG00000156421 +90594 ZNF439 HGNC:HGNC:20873|Ensembl:ENSG00000171291|Vega:OTTHUMG00000156527 +90624 LYRM7 MIM:615831|HGNC:HGNC:28072|Ensembl:ENSG00000186687|Vega:OTTHUMG00000128994 +90625 ERVH48-1 HGNC:HGNC:17216 +90627 STARD13 MIM:609866|HGNC:HGNC:19164|Ensembl:ENSG00000133121|Vega:OTTHUMG00000016708 +90632 LINC00473 HGNC:HGNC:21160|Ensembl:ENSG00000223414 +90634 N4BP2L1 HGNC:HGNC:25037|Ensembl:ENSG00000139597|Vega:OTTHUMG00000016697 +90637 ZFAND2A MIM:610699|HGNC:HGNC:28073|Ensembl:ENSG00000178381|Vega:OTTHUMG00000119019 +90639 COX19 MIM:610429|HGNC:HGNC:28074|Ensembl:ENSG00000240230|Vega:OTTHUMG00000151476 +90649 ZNF486 HGNC:HGNC:20807|Ensembl:ENSG00000256229|Vega:OTTHUMG00000179731 +90655 TGIF2LY MIM:400025|HGNC:HGNC:18569|Ensembl:ENSG00000176679|Vega:OTTHUMG00000036153 +90665 TBL1Y MIM:400033|HGNC:HGNC:18502|Ensembl:ENSG00000092377|Vega:OTTHUMG00000035299 +90668 CARMIL3 MIM:614716|HGNC:HGNC:20272|Ensembl:ENSG00000186648|Vega:OTTHUMG00000172023 +90673 PPP1R3E HGNC:HGNC:14943|Ensembl:ENSG00000235194|Vega:OTTHUMG00000172116 +90678 LRSAM1 MIM:610933|HGNC:HGNC:25135|Ensembl:ENSG00000148356|Vega:OTTHUMG00000020701 +90693 CCDC126 HGNC:HGNC:22398|Ensembl:ENSG00000169193|Vega:OTTHUMG00000128461 +90701 SEC11C HGNC:HGNC:23400|Ensembl:ENSG00000166562|Vega:OTTHUMG00000132762 +90736 FAM104B HGNC:HGNC:25085|Ensembl:ENSG00000182518|Vega:OTTHUMG00000021646 +90737 PAGE5 HGNC:HGNC:29992|Ensembl:ENSG00000158639|Vega:OTTHUMG00000021650 +90768 LOC90768 - +90780 PYGO2 MIM:606903|HGNC:HGNC:30257|Ensembl:ENSG00000163348|Vega:OTTHUMG00000037370 +90799 CEP95 HGNC:HGNC:25141|Ensembl:ENSG00000258890|Vega:OTTHUMG00000179174 +90806 ANGEL2 HGNC:HGNC:30534|Ensembl:ENSG00000174606|Vega:OTTHUMG00000036927 +90809 TMEM55B MIM:609865|HGNC:HGNC:19299|Ensembl:ENSG00000165782|Vega:OTTHUMG00000029545 +90826 PRMT9 MIM:616125|HGNC:HGNC:25099|Ensembl:ENSG00000164169|Vega:OTTHUMG00000161361 +90827 ZNF479 MIM:617444|HGNC:HGNC:23258|Ensembl:ENSG00000185177|Vega:OTTHUMG00000156682 +90835 CCDC189 HGNC:HGNC:28078|Ensembl:ENSG00000196118|Vega:OTTHUMG00000167926 +90843 TCEAL8 HGNC:HGNC:28683|Ensembl:ENSG00000180964|Vega:OTTHUMG00000022094 +90850 ZNF598 MIM:617508|HGNC:HGNC:28079|Ensembl:ENSG00000167962|Vega:OTTHUMG00000176955 +90853 SPOCD1 HGNC:HGNC:26338|Ensembl:ENSG00000134668|Vega:OTTHUMG00000003879 +90859 NT5C3AP1 HGNC:HGNC:18530 +90861 JPT2 HGNC:HGNC:14137|Ensembl:ENSG00000206053|Vega:OTTHUMG00000047859 +90864 SPSB3 MIM:611659|HGNC:HGNC:30629|Ensembl:ENSG00000162032|Vega:OTTHUMG00000176746 +90865 IL33 MIM:608678|HGNC:HGNC:16028|Ensembl:ENSG00000137033|Vega:OTTHUMG00000019516 +90871 DMAC1 MIM:617261|HGNC:HGNC:30536|Ensembl:ENSG00000137038|Vega:OTTHUMG00000019539 +90874 ZNF697 HGNC:HGNC:32034|Ensembl:ENSG00000143067|Vega:OTTHUMG00000012962 +90933 TRIM41 MIM:610530|HGNC:HGNC:19013|Ensembl:ENSG00000146063|Vega:OTTHUMG00000130965 +90952 ESAM MIM:614281|HGNC:HGNC:17474|Ensembl:ENSG00000149564|Vega:OTTHUMG00000151986 +90956 ADCK2 HGNC:HGNC:19039|Ensembl:ENSG00000133597|Vega:OTTHUMG00000157409 +90957 DHX57 HGNC:HGNC:20086|Ensembl:ENSG00000163214|Vega:OTTHUMG00000102103 +90987 ZNF251 HGNC:HGNC:13045|Ensembl:ENSG00000198169|Vega:OTTHUMG00000165189 +90990 KIFC2 MIM:615216|HGNC:HGNC:29530|Ensembl:ENSG00000167702|Vega:OTTHUMG00000165133 +90993 CREB3L1 MIM:616215|HGNC:HGNC:18856|Ensembl:ENSG00000157613|Vega:OTTHUMG00000166423 +91010 FMNL3 MIM:616288|HGNC:HGNC:23698|Ensembl:ENSG00000161791|Vega:OTTHUMG00000169651 +91012 CERS5 MIM:615335|HGNC:HGNC:23749|Ensembl:ENSG00000139624|Vega:OTTHUMG00000169819 +91039 DPP9 MIM:608258|HGNC:HGNC:18648|Ensembl:ENSG00000142002|Vega:OTTHUMG00000182040 +91050 CCDC149 HGNC:HGNC:25405|Ensembl:ENSG00000181982|Vega:OTTHUMG00000160308 +91056 AP5B1 MIM:614367|HGNC:HGNC:25104|Ensembl:ENSG00000254470|Vega:OTTHUMG00000166593 +91057 CCDC34 MIM:612324|HGNC:HGNC:25079|Ensembl:ENSG00000109881|Vega:OTTHUMG00000166211 +91074 ANKRD30A MIM:610856|HGNC:HGNC:17234|Ensembl:ENSG00000148513|Vega:OTTHUMG00000017968 +91107 TRIM47 MIM:611041|HGNC:HGNC:19020|Ensembl:ENSG00000132481|Vega:OTTHUMG00000179916 +91120 ZNF682 HGNC:HGNC:28857|Ensembl:ENSG00000197124|Vega:OTTHUMG00000182650 +91133 L3MBTL4 MIM:617135|HGNC:HGNC:26677|Ensembl:ENSG00000154655|Vega:OTTHUMG00000178980 +91137 SLC25A46 MIM:610826|HGNC:HGNC:25198|Ensembl:ENSG00000164209|Vega:OTTHUMG00000128794 +91147 TMEM67 MIM:609884|HGNC:HGNC:28396|Ensembl:ENSG00000164953|Vega:OTTHUMG00000153119 +91149 RAPGEF4-AS1 HGNC:HGNC:28081|Ensembl:ENSG00000228016 +91151 TIGD7 MIM:612969|HGNC:HGNC:18331|Ensembl:ENSG00000140993|Vega:OTTHUMG00000129325 +91156 IGFN1 MIM:617309|HGNC:HGNC:24607|Ensembl:ENSG00000163395 +91179 SCARF2 MIM:613619|HGNC:HGNC:19869|Ensembl:ENSG00000244486|Vega:OTTHUMG00000150779 +91181 NUP210L HGNC:HGNC:29915|Ensembl:ENSG00000143552|Vega:OTTHUMG00000035852 +91219 ABHD17AP5 HGNC:HGNC:34043 +91227 GGTLC2 MIM:612339|HGNC:HGNC:18596|Ensembl:ENSG00000100121|Vega:OTTHUMG00000151177 +91252 SLC39A13 MIM:608735|HGNC:HGNC:20859|Ensembl:ENSG00000165915|Vega:OTTHUMG00000166890 +91272 BOD1 MIM:616745|HGNC:HGNC:25114|Ensembl:ENSG00000145919|Vega:OTTHUMG00000130540 +91283 MSANTD3 HGNC:HGNC:23370|Ensembl:ENSG00000066697|Vega:OTTHUMG00000020365 +91289 LMF2 HGNC:HGNC:25096|Ensembl:ENSG00000100258|Vega:OTTHUMG00000150206 +91298 C12orf29 HGNC:HGNC:25322|Ensembl:ENSG00000133641|Vega:OTTHUMG00000169870 +91300 R3HDM4 HGNC:HGNC:28270|Ensembl:ENSG00000198858|Vega:OTTHUMG00000181899 +91304 TMEM259 MIM:611011|HGNC:HGNC:17039|Ensembl:ENSG00000182087|Vega:OTTHUMG00000181905 +91316 GUSBP11 HGNC:HGNC:42325|Ensembl:ENSG00000228315 +91319 DERL3 MIM:610305|HGNC:HGNC:14236|Ensembl:ENSG00000099958|Vega:OTTHUMG00000150743 +91351 DDX60L MIM:616725|HGNC:HGNC:26429|Ensembl:ENSG00000181381|Vega:OTTHUMG00000161412 +91353 IGLL3P HGNC:HGNC:5872 +91355 LRP5L HGNC:HGNC:25323|Ensembl:ENSG00000100068|Vega:OTTHUMG00000150900 +91368 CDKN2AIPNL HGNC:HGNC:30545|Ensembl:ENSG00000237190|Vega:OTTHUMG00000129123 +91369 ANKRD40 HGNC:HGNC:28233|Ensembl:ENSG00000154945|Vega:OTTHUMG00000162255 +91370 MGC20647 Ensembl:ENSG00000268812 +91373 UAP1L1 HGNC:HGNC:28082|Ensembl:ENSG00000197355|Vega:OTTHUMG00000020962 +91380 SNORD107 HGNC:HGNC:32771|Ensembl:ENSG00000276314 +91392 ZNF502 HGNC:HGNC:23718|Ensembl:ENSG00000196653|Vega:OTTHUMG00000133086 +91404 SESTD1 HGNC:HGNC:18379|Ensembl:ENSG00000187231|Vega:OTTHUMG00000154554 +91405 PLEKHA3P1 HGNC:HGNC:19648 +91408 BTF3L4 HGNC:HGNC:30547|Ensembl:ENSG00000134717|Vega:OTTHUMG00000008960 +91409 CCDC74B HGNC:HGNC:25267|Ensembl:ENSG00000152076|Vega:OTTHUMG00000131629 +91419 ATP23 HGNC:HGNC:29452|Ensembl:ENSG00000166896|Vega:OTTHUMG00000170493 +91433 RCCD1 HGNC:HGNC:30457|Ensembl:ENSG00000166965|Vega:OTTHUMG00000171684 +91442 FAAP24 MIM:610884|HGNC:HGNC:28467|Ensembl:ENSG00000131944|Vega:OTTHUMG00000180339 +91445 RNF185 HGNC:HGNC:26783|Ensembl:ENSG00000138942|Vega:OTTHUMG00000151253 +91450 LOC91450 - +91452 ACBD5 MIM:616618|HGNC:HGNC:23338|Ensembl:ENSG00000107897|Vega:OTTHUMG00000017854 +91461 PKDCC MIM:614150|HGNC:HGNC:25123|Ensembl:ENSG00000162878|Vega:OTTHUMG00000152303 +91464 ISX MIM:612019|HGNC:HGNC:28084|Ensembl:ENSG00000175329|Vega:OTTHUMG00000150962 +91522 COL23A1 MIM:610043|HGNC:HGNC:22990|Ensembl:ENSG00000050767|Vega:OTTHUMG00000130890 +91523 PCED1B HGNC:HGNC:28255|Ensembl:ENSG00000179715|Vega:OTTHUMG00000169617 +91526 ANKRD44 HGNC:HGNC:25259|Ensembl:ENSG00000065413|Vega:OTTHUMG00000154411 +91543 RSAD2 MIM:607810|HGNC:HGNC:30908|Ensembl:ENSG00000134321|Vega:OTTHUMG00000090352 +91544 UBXN11 MIM:609151|HGNC:HGNC:30600|Ensembl:ENSG00000158062|Vega:OTTHUMG00000003382 +91548 LOC91548 - +91561 RPS2P40 HGNC:HGNC:35541 +91574 C12orf65 MIM:613541|HGNC:HGNC:26784|Ensembl:ENSG00000130921|Vega:OTTHUMG00000168852 +91582 RPS19BP1 MIM:610225|HGNC:HGNC:28749|Ensembl:ENSG00000187051|Vega:OTTHUMG00000151101 +91584 PLXNA4 MIM:604280|HGNC:HGNC:9102|Ensembl:ENSG00000221866|Vega:OTTHUMG00000155108 +91603 ZNF830 HGNC:HGNC:28291|Ensembl:ENSG00000198783|Vega:OTTHUMG00000179771 +91607 SLFN11 MIM:614953|HGNC:HGNC:26633|Ensembl:ENSG00000172716|Vega:OTTHUMG00000132948 +91608 RASL10B MIM:612128|HGNC:HGNC:30295|Ensembl:ENSG00000270885|Vega:OTTHUMG00000188385 +91612 CHURC1 MIM:608577|HGNC:HGNC:20099|Ensembl:ENSG00000258289|Vega:OTTHUMG00000170218 +91614 DEPDC7 MIM:612294|HGNC:HGNC:29899|Ensembl:ENSG00000121690|Vega:OTTHUMG00000166242 +91624 NEXN MIM:613121|HGNC:HGNC:29557|Ensembl:ENSG00000162614|Vega:OTTHUMG00000040533 +91646 TDRD12 HGNC:HGNC:25044|Ensembl:ENSG00000173809|Vega:OTTHUMG00000177230 +91647 ATPAF2 MIM:608918|HGNC:HGNC:18802|Ensembl:ENSG00000171953|Vega:OTTHUMG00000059354 +91653 BOC MIM:608708|HGNC:HGNC:17173|Ensembl:ENSG00000144857|Vega:OTTHUMG00000159305 +91661 ZNF765 HGNC:HGNC:25092|Ensembl:ENSG00000196417|Vega:OTTHUMG00000163079 +91662 NLRP12 MIM:609648|HGNC:HGNC:22938|Ensembl:ENSG00000142405|Vega:OTTHUMG00000060776 +91663 MYADM MIM:609959|HGNC:HGNC:7544|Ensembl:ENSG00000179820|Vega:OTTHUMG00000060775 +91664 ZNF845 HGNC:HGNC:25112|Ensembl:ENSG00000213799|Vega:OTTHUMG00000182920 +91683 SYT12 MIM:606436|HGNC:HGNC:18381|Ensembl:ENSG00000173227|Vega:OTTHUMG00000167101 +91687 CENPL MIM:611503|HGNC:HGNC:17879|Ensembl:ENSG00000120334|Vega:OTTHUMG00000034802 +91689 SMDT1 MIM:615588|HGNC:HGNC:25055|Ensembl:ENSG00000183172|Vega:OTTHUMG00000151286 +91694 LONRF1 HGNC:HGNC:26302|Ensembl:ENSG00000154359|Vega:OTTHUMG00000165475 +91695 RRP7BP HGNC:HGNC:30454|Ensembl:ENSG00000182841 +91703 ACY3 MIM:614413|HGNC:HGNC:24104|Ensembl:ENSG00000132744|Vega:OTTHUMG00000167283 +91734 IDI2 MIM:615389|HGNC:HGNC:23487|Ensembl:ENSG00000148377|Vega:OTTHUMG00000017537 +91746 YTHDC1 MIM:617283|HGNC:HGNC:30626|Ensembl:ENSG00000083896|Vega:OTTHUMG00000129306 +91748 ELMSAN1 HGNC:HGNC:19853|Ensembl:ENSG00000156030|Vega:OTTHUMG00000150359 +91749 MFSD4B MIM:617331|HGNC:HGNC:21053|Ensembl:ENSG00000173214|Vega:OTTHUMG00000015372 +91750 LIN52 HGNC:HGNC:19856|Ensembl:ENSG00000205659|Vega:OTTHUMG00000171204 +91752 ZNF804A MIM:612282|HGNC:HGNC:21711|Ensembl:ENSG00000170396|Vega:OTTHUMG00000132625 +91754 NEK9 MIM:609798|HGNC:HGNC:18591|Ensembl:ENSG00000119638|Vega:OTTHUMG00000171768 +91768 CABLES1 MIM:609194|HGNC:HGNC:25097|Ensembl:ENSG00000134508|Vega:OTTHUMG00000179186 +91775 NXPE3 HGNC:HGNC:28238|Ensembl:ENSG00000144815|Vega:OTTHUMG00000159179 +91782 CHMP7 MIM:611130|HGNC:HGNC:28439|Ensembl:ENSG00000147457|Vega:OTTHUMG00000131785 +91801 ALKBH8 MIM:613306|HGNC:HGNC:25189|Ensembl:ENSG00000137760|Vega:OTTHUMG00000157008 +91807 MYLK3 MIM:612147|HGNC:HGNC:29826|Ensembl:ENSG00000140795|Vega:OTTHUMG00000132543 +91828 EXOC3L4 HGNC:HGNC:20120|Ensembl:ENSG00000205436|Vega:OTTHUMG00000171888 +91833 WDR20 HGNC:HGNC:19667|Ensembl:ENSG00000140153|Vega:OTTHUMG00000171753 +91851 CHRDL1 MIM:300350|HGNC:HGNC:29861|Ensembl:ENSG00000101938|Vega:OTTHUMG00000022199 +91860 CALML4 HGNC:HGNC:18445|Ensembl:ENSG00000129007|Vega:OTTHUMG00000133287 +91862 MARVELD3 MIM:614094|HGNC:HGNC:30525|Ensembl:ENSG00000140832|Vega:OTTHUMG00000137591 +91869 RFT1 MIM:611908|HGNC:HGNC:30220|Ensembl:ENSG00000163933|Vega:OTTHUMG00000074035 +91875 TTC5 HGNC:HGNC:19274|Ensembl:ENSG00000136319|Vega:OTTHUMG00000029506 +91893 FDXACB1 HGNC:HGNC:25110|Ensembl:ENSG00000255561|Vega:OTTHUMG00000166795 +91894 C11orf52 HGNC:HGNC:30531|Ensembl:ENSG00000149300|Vega:OTTHUMG00000166888 +91937 TIMD4 MIM:610096|HGNC:HGNC:25132|Ensembl:ENSG00000145850|Vega:OTTHUMG00000130244 +91942 NDUFAF2 MIM:609653|HGNC:HGNC:28086|Ensembl:ENSG00000164182|Vega:OTTHUMG00000131221 +91947 ARRDC4 HGNC:HGNC:28087|Ensembl:ENSG00000140450|Vega:OTTHUMG00000149849 +91948 LINC00923 HGNC:HGNC:28088|Ensembl:ENSG00000251209 +91949 COG7 MIM:606978|HGNC:HGNC:18622|Ensembl:ENSG00000168434|Vega:OTTHUMG00000094807 +91966 CXorf40A MIM:300954|HGNC:HGNC:28089|Ensembl:ENSG00000197620|Vega:OTTHUMG00000022622 +91975 ZNF300 MIM:612429|HGNC:HGNC:13091|Ensembl:ENSG00000145908|Vega:OTTHUMG00000130076 +91977 MYOZ3 MIM:610735|HGNC:HGNC:18565|Ensembl:ENSG00000164591|Vega:OTTHUMG00000130077 +91978 TPGS1 HGNC:HGNC:25058|Ensembl:ENSG00000141933|Vega:OTTHUMG00000180557 +92002 CCNQ MIM:300708|HGNC:HGNC:28434|Ensembl:ENSG00000262919|Vega:OTTHUMG00000024206 +92014 SLC25A51 HGNC:HGNC:23323|Ensembl:ENSG00000122696|Vega:OTTHUMG00000019935 +92017 SNX29 HGNC:HGNC:30542|Ensembl:ENSG00000048471|Vega:OTTHUMG00000129827 +92070 CTBP1-AS2 HGNC:HGNC:28307 +92086 GGTLC1 MIM:612338|HGNC:HGNC:16437|Ensembl:ENSG00000149435|Vega:OTTHUMG00000032095 +92092 ZC3HAV1L HGNC:HGNC:22423|Ensembl:ENSG00000146858|Vega:OTTHUMG00000157229 +92104 TTC30A HGNC:HGNC:25853|Ensembl:ENSG00000197557|Vega:OTTHUMG00000132528 +92105 INTS4 MIM:611348|HGNC:HGNC:25048|Ensembl:ENSG00000149262|Vega:OTTHUMG00000166629 +92106 OXNAD1 HGNC:HGNC:25128|Ensembl:ENSG00000154814|Vega:OTTHUMG00000129867 +92126 DSEL MIM:611125|HGNC:HGNC:18144|Ensembl:ENSG00000171451|Vega:OTTHUMG00000132804 +92129 RIPPLY1 MIM:300575|HGNC:HGNC:25117|Ensembl:ENSG00000147223|Vega:OTTHUMG00000022153 +92140 MTDH MIM:610323|HGNC:HGNC:29608|Ensembl:ENSG00000147649|Vega:OTTHUMG00000164692 +92154 MTSS1L MIM:616951|HGNC:HGNC:25094|Ensembl:ENSG00000132613|Vega:OTTHUMG00000177023 +92162 TMEM88 HGNC:HGNC:32371|Ensembl:ENSG00000167874|Vega:OTTHUMG00000178022 +92170 MTG1 HGNC:HGNC:32159|Ensembl:ENSG00000148824|Vega:OTTHUMG00000166564 +92181 UBTD2 MIM:610174|HGNC:HGNC:24463|Ensembl:ENSG00000168246|Vega:OTTHUMG00000130519 +92196 DAPL1 HGNC:HGNC:21490|Ensembl:ENSG00000163331|Vega:OTTHUMG00000153970 +92211 CDHR1 MIM:609502|HGNC:HGNC:14550|Ensembl:ENSG00000148600|Vega:OTTHUMG00000018634 +92235 DUSP27 HGNC:HGNC:25034|Ensembl:ENSG00000198842|Vega:OTTHUMG00000034434 +92241 RCSD1 MIM:610579|HGNC:HGNC:28310|Ensembl:ENSG00000198771|Vega:OTTHUMG00000035318 +92249 LINC01278 HGNC:HGNC:28090|Ensembl:ENSG00000235437 +92255 LMBRD2 HGNC:HGNC:25287|Ensembl:ENSG00000164187|Vega:OTTHUMG00000162150 +92259 MRPS36 MIM:611996|HGNC:HGNC:16631|Ensembl:ENSG00000134056|Vega:OTTHUMG00000162443 +92270 ATP6AP1L HGNC:HGNC:28091|Ensembl:ENSG00000205464|Vega:OTTHUMG00000162558 +92283 ZNF461 MIM:608640|HGNC:HGNC:21629|Ensembl:ENSG00000197808|Vega:OTTHUMG00000180832 +92285 ZNF585B HGNC:HGNC:30948|Ensembl:ENSG00000245680|Vega:OTTHUMG00000048165 +92291 CAPN13 MIM:610228|HGNC:HGNC:16663|Ensembl:ENSG00000162949|Vega:OTTHUMG00000152053 +92292 GLYATL1 MIM:614761|HGNC:HGNC:30519|Ensembl:ENSG00000166840|Vega:OTTHUMG00000167221 +92293 TMEM132C HGNC:HGNC:25436|Ensembl:ENSG00000181234|Vega:OTTHUMG00000163736 +92304 SCGB3A1 MIM:606500|HGNC:HGNC:18384|Ensembl:ENSG00000161055|Vega:OTTHUMG00000130936 +92305 TMEM129 MIM:615975|HGNC:HGNC:25137|Ensembl:ENSG00000168936|Vega:OTTHUMG00000121150 +92312 MEX3A MIM:611007|HGNC:HGNC:33482|Ensembl:ENSG00000254726|Vega:OTTHUMG00000017465 +92335 STRADA MIM:608626|HGNC:HGNC:30172|Ensembl:ENSG00000266173|Vega:OTTHUMG00000178908 +92340 PRR29 HGNC:HGNC:25673|Ensembl:ENSG00000224383|Vega:OTTHUMG00000178594 +92342 METTL18 MIM:615255|HGNC:HGNC:28793|Ensembl:ENSG00000171806|Vega:OTTHUMG00000035813 +92344 GORAB MIM:607983|HGNC:HGNC:25676|Ensembl:ENSG00000120370|Vega:OTTHUMG00000035228 +92345 NAF1 HGNC:HGNC:25126|Ensembl:ENSG00000145414|Vega:OTTHUMG00000161370 +92346 C1orf105 HGNC:HGNC:29591|Ensembl:ENSG00000180999|Vega:OTTHUMG00000034750 +92359 CRB3 MIM:609737|HGNC:HGNC:20237|Ensembl:ENSG00000130545|Vega:OTTHUMG00000181828 +92369 SPSB4 MIM:611660|HGNC:HGNC:30630|Ensembl:ENSG00000175093|Vega:OTTHUMG00000160223 +92370 PXYLP1 HGNC:HGNC:26303|Ensembl:ENSG00000155893|Vega:OTTHUMG00000160171 +92399 MRRF MIM:604602|HGNC:HGNC:7234|Ensembl:ENSG00000148187|Vega:OTTHUMG00000020600 +92400 RBM18 HGNC:HGNC:28413|Ensembl:ENSG00000119446|Vega:OTTHUMG00000020602 +92421 CHMP4C MIM:610899|HGNC:HGNC:30599|Ensembl:ENSG00000164695|Vega:OTTHUMG00000164726 +92427 RPS2P4 HGNC:HGNC:19814 +92482 BBIP1 MIM:613605|HGNC:HGNC:28093|Ensembl:ENSG00000214413|Vega:OTTHUMG00000019046 +92483 LDHAL6B HGNC:HGNC:21481|Ensembl:ENSG00000171989|Vega:OTTHUMG00000132714 +92507 RPS4XP2 HGNC:HGNC:16563 +92521 SPECC1 MIM:608793|HGNC:HGNC:30615|Ensembl:ENSG00000128487|Vega:OTTHUMG00000179808 +92552 ATXN3L MIM:300920|HGNC:HGNC:24173|Ensembl:ENSG00000123594|Vega:OTTHUMG00000021146 +92558 BICDL1 MIM:617002|HGNC:HGNC:28095|Ensembl:ENSG00000135127|Vega:OTTHUMG00000169311 +92565 FANK1 MIM:611640|HGNC:HGNC:23527|Ensembl:ENSG00000203780|Vega:OTTHUMG00000019241 +92579 G6PC3 MIM:611045|HGNC:HGNC:24861|Ensembl:ENSG00000141349|Vega:OTTHUMG00000181805 +92591 ASB16 MIM:615056|HGNC:HGNC:19768|Ensembl:ENSG00000161664|Vega:OTTHUMG00000181809 +92595 ZNF764 HGNC:HGNC:28200|Ensembl:ENSG00000169951|Vega:OTTHUMG00000132406 +92597 MOB1B MIM:609282|HGNC:HGNC:29801|Ensembl:ENSG00000173542|Vega:OTTHUMG00000160844 +92609 TIMM50 MIM:607381|HGNC:HGNC:23656|Ensembl:ENSG00000105197|Vega:OTTHUMG00000183066 +92610 TIFA MIM:609028|HGNC:HGNC:19075|Ensembl:ENSG00000145365|Vega:OTTHUMG00000161066 +92659 MAFG-AS1 HGNC:HGNC:43649|Ensembl:ENSG00000265688 +92667 MGME1 MIM:615076|HGNC:HGNC:16205|Ensembl:ENSG00000125871|Vega:OTTHUMG00000031955 +92675 DTD1 MIM:610996|HGNC:HGNC:16219|Ensembl:ENSG00000125821|Vega:OTTHUMG00000031980 +92682 RPS15AP1 HGNC:HGNC:16598 +92689 FAM114A1 HGNC:HGNC:25087|Ensembl:ENSG00000197712|Vega:OTTHUMG00000128583 +92691 TMEM169 HGNC:HGNC:25130|Ensembl:ENSG00000163449|Vega:OTTHUMG00000133053 +92703 TMEM183A HGNC:HGNC:20173|Ensembl:ENSG00000163444|Vega:OTTHUMG00000042051 +92714 ARRDC1 HGNC:HGNC:28633|Ensembl:ENSG00000197070|Vega:OTTHUMG00000020993 +92715 DPH7 MIM:613210|HGNC:HGNC:25199|Ensembl:ENSG00000148399|Vega:OTTHUMG00000020991 +92736 OTOP2 MIM:607827|HGNC:HGNC:19657|Ensembl:ENSG00000183034|Vega:OTTHUMG00000179215 +92737 DNER MIM:607299|HGNC:HGNC:24456|Ensembl:ENSG00000187957|Vega:OTTHUMG00000153637 +92745 SLC38A5 MIM:300649|HGNC:HGNC:18070|Ensembl:ENSG00000017483|Vega:OTTHUMG00000024117 +92747 BPIFB1 HGNC:HGNC:16108|Ensembl:ENSG00000125999|Vega:OTTHUMG00000032252 +92749 DRC1 MIM:615288|HGNC:HGNC:24245|Ensembl:ENSG00000157856|Vega:OTTHUMG00000125531 +92755 TUBBP1 HGNC:HGNC:12414 +92797 HELB MIM:614539|HGNC:HGNC:17196|Ensembl:ENSG00000127311|Vega:OTTHUMG00000169006 +92799 SHKBP1 MIM:617322|HGNC:HGNC:19214|Ensembl:ENSG00000160410|Vega:OTTHUMG00000182602 +92806 CENPBD1 HGNC:HGNC:28272|Ensembl:ENSG00000177946|Vega:OTTHUMG00000173040 +92815 HIST3H2A MIM:615015|HGNC:HGNC:20507|Ensembl:ENSG00000181218|Vega:OTTHUMG00000040046 +92822 ZNF276 MIM:608460|HGNC:HGNC:23330|Ensembl:ENSG00000158805|Vega:OTTHUMG00000138050 +92840 REEP6 MIM:609346|HGNC:HGNC:30078|Ensembl:ENSG00000115255|Vega:OTTHUMG00000180072 +92856 IMP4 MIM:612981|HGNC:HGNC:30856|Ensembl:ENSG00000136718|Vega:OTTHUMG00000131627 +92906 HNRNPLL MIM:611208|HGNC:HGNC:25127|Ensembl:ENSG00000143889|Vega:OTTHUMG00000102075 +92912 UBE2Q2 MIM:612501|HGNC:HGNC:19248|Ensembl:ENSG00000140367|Vega:OTTHUMG00000142839 +92922 CCDC102A HGNC:HGNC:28097|Ensembl:ENSG00000135736|Vega:OTTHUMG00000133472 +92935 MARS2 MIM:609728|HGNC:HGNC:25133|Ensembl:ENSG00000247626|Vega:OTTHUMG00000154487 +92949 ADAMTSL1 MIM:609198|HGNC:HGNC:14632|Ensembl:ENSG00000178031|Vega:OTTHUMG00000019604 +92960 PEX11G MIM:607583|HGNC:HGNC:20208|Ensembl:ENSG00000104883|Vega:OTTHUMG00000182044 +92973 LINC00950 HGNC:HGNC:28098 +92979 MARCH9 MIM:613336|HGNC:HGNC:25139|Ensembl:ENSG00000139266|Vega:OTTHUMG00000170456 +92999 ZBTB47 HGNC:HGNC:26955|Ensembl:ENSG00000114853|Vega:OTTHUMG00000156207 +93010 B3GNT7 MIM:615313|HGNC:HGNC:18811|Ensembl:ENSG00000156966|Vega:OTTHUMG00000153880 +93034 NT5C1B MIM:610526|HGNC:HGNC:17818|Ensembl:ENSG00000185013|Vega:OTTHUMG00000151765 +93035 PKHD1L1 MIM:607843|HGNC:HGNC:20313|Ensembl:ENSG00000205038|Vega:OTTHUMG00000164934 +93058 COQ10A HGNC:HGNC:26515|Ensembl:ENSG00000135469|Vega:OTTHUMG00000170283 +93081 TEX30 HGNC:HGNC:25188|Ensembl:ENSG00000151287|Vega:OTTHUMG00000017306 +93082 NEURL3 MIM:617206|HGNC:HGNC:25162|Ensembl:ENSG00000163121|Vega:OTTHUMG00000128645 +93099 DMKN MIM:617211|HGNC:HGNC:25063|Ensembl:ENSG00000161249|Vega:OTTHUMG00000048101 +93100 NAPRT MIM:611552|HGNC:HGNC:30450|Ensembl:ENSG00000147813|Vega:OTTHUMG00000156942 +93107 KCNG4 MIM:607603|HGNC:HGNC:19697|Ensembl:ENSG00000168418|Vega:OTTHUMG00000137638 +93109 TMEM44 HGNC:HGNC:25120|Ensembl:ENSG00000145014|Vega:OTTHUMG00000156023 +93129 ORAI3 MIM:610930|HGNC:HGNC:28185|Ensembl:ENSG00000175938|Vega:OTTHUMG00000176768 +93134 ZNF561 HGNC:HGNC:28684|Ensembl:ENSG00000171469|Vega:OTTHUMG00000157054 +93144 RPS10P5 HGNC:HGNC:15795 +93145 OLFM2 MIM:617492|HGNC:HGNC:17189|Ensembl:ENSG00000105088|Vega:OTTHUMG00000180390 +93164 HTR7P1 HGNC:HGNC:30411|Ensembl:ENSG00000183935 +93166 PRDM6 MIM:616982|HGNC:HGNC:9350|Ensembl:ENSG00000061455|Vega:OTTHUMG00000150469 +93183 PIGM MIM:610273|HGNC:HGNC:18858|Ensembl:ENSG00000143315|Vega:OTTHUMG00000024081 +93185 IGSF8 MIM:606644|HGNC:HGNC:17813|Ensembl:ENSG00000162729|Vega:OTTHUMG00000024075 +93190 C1orf158 HGNC:HGNC:28567|Ensembl:ENSG00000157330|Vega:OTTHUMG00000001888 +93202 TXNP1 HGNC:HGNC:49481 +93210 PGAP3 MIM:611801|HGNC:HGNC:23719|Ensembl:ENSG00000161395|Vega:OTTHUMG00000179110 +93233 CCDC114 MIM:615038|HGNC:HGNC:26560|Ensembl:ENSG00000105479|Vega:OTTHUMG00000156161 +93273 LEMD1 MIM:610480|HGNC:HGNC:18725|Ensembl:ENSG00000186007|Vega:OTTHUMG00000037201 +93323 HAUS8 MIM:613434|HGNC:HGNC:30532|Ensembl:ENSG00000131351|Vega:OTTHUMG00000182672 +93343 MVB12A HGNC:HGNC:25153|Ensembl:ENSG00000141971|Vega:OTTHUMG00000166252 +93349 SP140L HGNC:HGNC:25105|Ensembl:ENSG00000185404|Vega:OTTHUMG00000153730 +93377 OPALIN MIM:617200|HGNC:HGNC:20707|Ensembl:ENSG00000197430|Vega:OTTHUMG00000018831 +93380 MMGT1 HGNC:HGNC:28100|Ensembl:ENSG00000169446|Vega:OTTHUMG00000022499 +93408 MYL10 MIM:617177|HGNC:HGNC:29825|Ensembl:ENSG00000106436|Vega:OTTHUMG00000157137 +93426 SYCE1 MIM:611486|HGNC:HGNC:28852|Ensembl:ENSG00000171772|Vega:OTTHUMG00000019321 +93429 LOC93429 Ensembl:ENSG00000268460 +93432 MGAM2 HGNC:HGNC:28101|Ensembl:ENSG00000257743|Vega:OTTHUMG00000158558 +93436 ARMC6 HGNC:HGNC:25049|Ensembl:ENSG00000105676|Vega:OTTHUMG00000169271 +93463 LOC93463 Ensembl:ENSG00000124835 +93474 ZNF670 HGNC:HGNC:28167|Ensembl:ENSG00000277462|Vega:OTTHUMG00000040868 +93487 MAPK1IP1L MIM:617226|HGNC:HGNC:19840|Ensembl:ENSG00000168175|Vega:OTTHUMG00000171029 +93492 TPTE2 MIM:606791|HGNC:HGNC:17299|Ensembl:ENSG00000132958|Vega:OTTHUMG00000016493 +93517 SDR42E1 MIM:616164|HGNC:HGNC:29834|Ensembl:ENSG00000184860|Vega:OTTHUMG00000166148 +93550 ZFAND4 HGNC:HGNC:23504|Ensembl:ENSG00000172671|Vega:OTTHUMG00000018085 +93556 EGFEM1P HGNC:HGNC:25149 +93587 TRMT10A MIM:616013|HGNC:HGNC:28403|Ensembl:ENSG00000145331|Vega:OTTHUMG00000131025 +93589 CACNA2D4 MIM:608171|HGNC:HGNC:20202|Ensembl:ENSG00000151062|Vega:OTTHUMG00000168111 +93594 TBC1D31 HGNC:HGNC:30888|Ensembl:ENSG00000156787|Vega:OTTHUMG00000165081 +93611 FBXO44 MIM:609111|HGNC:HGNC:24847|Ensembl:ENSG00000132879|Vega:OTTHUMG00000002071 +93621 MRFAP1 MIM:616905|HGNC:HGNC:24549|Ensembl:ENSG00000179010|Vega:OTTHUMG00000125504 +93622 LOC93622 Ensembl:ENSG00000170846 +93624 TADA2B MIM:608790|HGNC:HGNC:30781|Ensembl:ENSG00000173011|Vega:OTTHUMG00000159983 +93627 TBCK MIM:616899|HGNC:HGNC:28261|Ensembl:ENSG00000145348|Vega:OTTHUMG00000131214 +93643 TJAP1 MIM:612658|HGNC:HGNC:17949|Ensembl:ENSG00000137221|Vega:OTTHUMG00000014736 +93649 MYOCD MIM:606127|HGNC:HGNC:16067|Ensembl:ENSG00000141052|Vega:OTTHUMG00000058767 +93650 ACP4 MIM:606362|HGNC:HGNC:14376|Ensembl:ENSG00000142513|Vega:OTTHUMG00000182961 +93653 ST7-AS1 HGNC:HGNC:16000|Ensembl:ENSG00000227199 +93654 ST7-AS2 HGNC:HGNC:16044|Ensembl:ENSG00000226367 +93655 ST7-OT3 HGNC:HGNC:16045|Ensembl:ENSG00000004866 +93659 CGB5 MIM:608825|HGNC:HGNC:16452|Ensembl:ENSG00000189052|Vega:OTTHUMG00000183337 +93661 CAPZA3 MIM:608722|HGNC:HGNC:24205|Ensembl:ENSG00000177938|Vega:OTTHUMG00000169001 +93663 ARHGAP18 MIM:613351|HGNC:HGNC:21035|Ensembl:ENSG00000146376|Vega:OTTHUMG00000015547 +93664 CADPS2 MIM:609978|HGNC:HGNC:16018|Ensembl:ENSG00000081803|Vega:OTTHUMG00000157093 +93668 HPYR1 HGNC:HGNC:16071|Ensembl:ENSG00000253521 +93948 RPS23P1 HGNC:HGNC:16043 +93953 GCNA MIM:300369|HGNC:HGNC:15805|Ensembl:ENSG00000147174|Vega:OTTHUMG00000033327 +93956 AOCH MIM:606049 +93973 ACTR8 HGNC:HGNC:14672|Ensembl:ENSG00000113812|Vega:OTTHUMG00000158279 +93974 ATPIF1 MIM:614981|HGNC:HGNC:871|Ensembl:ENSG00000130770|Vega:OTTHUMG00000003533 +93978 CLEC6A MIM:613579|HGNC:HGNC:14556|Ensembl:ENSG00000205846|Vega:OTTHUMG00000168672 +93979 CPA5 MIM:609561|HGNC:HGNC:15722|Ensembl:ENSG00000158525|Vega:OTTHUMG00000157824 +93980 DYRK1AIP1 HGNC:HGNC:14401 +93981 DYRK1AIP2 HGNC:HGNC:14459 +93983 DYT13 MIM:607671|HGNC:HGNC:3101 +93985 FGS3 MIM:300406|HGNC:HGNC:15596 +93986 FOXP2 MIM:605317|HGNC:HGNC:13875|Ensembl:ENSG00000128573|Vega:OTTHUMG00000023131 +93991 MRX77 MIM:300454|HGNC:HGNC:15824 +93993 NDUFB3P1 HGNC:HGNC:13673 +93994 NDUFB3P2 HGNC:HGNC:13674 +93995 NDUFB3P4 HGNC:HGNC:13676 +93996 NDUFB3P3 HGNC:HGNC:13675 +93997 NDUFB3P5 HGNC:HGNC:13677 +93999 OTSC2 MIM:605727|HGNC:HGNC:8520 +94003 PDB4 MIM:606263|HGNC:HGNC:16033 +94005 PIGS MIM:610271|HGNC:HGNC:14937|Ensembl:ENSG00000087111|Vega:OTTHUMG00000132604 +94008 SCA18 MIM:607458|HGNC:HGNC:15744 +94009 SERHL MIM:607979|HGNC:HGNC:14408|Ensembl:ENSG00000172250 +94014 TRICY1 MIM:609649|HGNC:HGNC:12302 +94015 TTYH2 MIM:608855|HGNC:HGNC:13877|Ensembl:ENSG00000141540|Vega:OTTHUMG00000166018 +94017 TRS-TGA2-1 MIM:606171|HGNC:HGNC:16292 +94025 MUC16 MIM:606154|HGNC:HGNC:15582|Ensembl:ENSG00000181143|Vega:OTTHUMG00000169191 +94026 POM121L2 HGNC:HGNC:13973|Ensembl:ENSG00000158553|Vega:OTTHUMG00000014475 +94027 CGB7 MIM:608826|HGNC:HGNC:16451|Ensembl:ENSG00000196337|Vega:OTTHUMG00000183339 +94030 LRRC4B HGNC:HGNC:25042|Ensembl:ENSG00000131409|Vega:OTTHUMG00000183063 +94031 HTRA3 MIM:608785|HGNC:HGNC:30406|Ensembl:ENSG00000170801|Vega:OTTHUMG00000090561 +94032 CAMK2N2 MIM:608721|HGNC:HGNC:24197|Ensembl:ENSG00000163888|Vega:OTTHUMG00000156821 +94033 FTMT MIM:608847|HGNC:HGNC:17345|Ensembl:ENSG00000181867|Vega:OTTHUMG00000128912 +94039 ZNF101 MIM:603983|HGNC:HGNC:12881|Ensembl:ENSG00000181896|Vega:OTTHUMG00000167736 +94056 SYAP1 HGNC:HGNC:16273|Ensembl:ENSG00000169895|Vega:OTTHUMG00000021192 +94059 LENG9 HGNC:HGNC:16306|Ensembl:ENSG00000275183|Vega:OTTHUMG00000188273 +94081 SFXN1 MIM:615569|HGNC:HGNC:16085|Ensembl:ENSG00000164466|Vega:OTTHUMG00000130555 +94086 HSPB9 MIM:608344|HGNC:HGNC:30589|Ensembl:ENSG00000260325|Vega:OTTHUMG00000133500 +94097 SFXN5 MIM:615572|HGNC:HGNC:16073|Ensembl:ENSG00000144040|Vega:OTTHUMG00000129775 +94101 ORMDL1 MIM:610073|HGNC:HGNC:16036|Ensembl:ENSG00000128699|Vega:OTTHUMG00000132661 +94103 ORMDL3 MIM:610075|HGNC:HGNC:16038|Ensembl:ENSG00000172057|Vega:OTTHUMG00000133249 +94104 PAXBP1 HGNC:HGNC:13579|Ensembl:ENSG00000159086|Vega:OTTHUMG00000064980 +94107 TMEM203 MIM:616499|HGNC:HGNC:28217|Ensembl:ENSG00000187713|Vega:OTTHUMG00000020985 +94115 CGB8 MIM:608827|HGNC:HGNC:16453|Ensembl:ENSG00000213030|Vega:OTTHUMG00000180609 +94120 SYTL3 HGNC:HGNC:15587|Ensembl:ENSG00000164674|Vega:OTTHUMG00000015916 +94121 SYTL4 MIM:300723|HGNC:HGNC:15588|Ensembl:ENSG00000102362|Vega:OTTHUMG00000022004 +94122 SYTL5 HGNC:HGNC:15589|Ensembl:ENSG00000147041|Vega:OTTHUMG00000033176 +94134 ARHGAP12 MIM:610577|HGNC:HGNC:16348|Ensembl:ENSG00000165322|Vega:OTTHUMG00000017911 +94137 RP1L1 MIM:608581|HGNC:HGNC:15946|Ensembl:ENSG00000183638|Vega:OTTHUMG00000163806 +94138 DFNA32 HGNC:HGNC:2804 +94139 DFNA34 HGNC:HGNC:2806 +94140 DFNA35 HGNC:HGNC:2807 +94144 CDRT2 HGNC:HGNC:14381 +94145 CDRT3 HGNC:HGNC:14382 +94148 CDRT5 HGNC:HGNC:14384 +94150 CDRT7 HGNC:HGNC:14386|Ensembl:ENSG00000259944 +94151 CDRT8 HGNC:HGNC:14387 +94153 CDRT10 HGNC:HGNC:14390 +94154 CDRT11 HGNC:HGNC:14391 +94155 CDRT12 HGNC:HGNC:14392 +94156 CDRT13 HGNC:HGNC:14393 +94158 CDRT15P1 HGNC:HGNC:33168 +94160 ABCC12 MIM:607041|HGNC:HGNC:14640|Ensembl:ENSG00000140798|Vega:OTTHUMG00000133143 +94161 SNORD46 HGNC:HGNC:10186|Ensembl:ENSG00000200913 +94162 SNORD38A HGNC:HGNC:30355|Ensembl:ENSG00000202031 +94163 SNORD38B HGNC:HGNC:30356|Ensembl:ENSG00000207421|Ensembl:ENSG00000281859 +94233 OPN4 MIM:606665|HGNC:HGNC:14449|Ensembl:ENSG00000122375|Vega:OTTHUMG00000018654 +94234 FOXQ1 MIM:612788|HGNC:HGNC:20951|Ensembl:ENSG00000164379|Vega:OTTHUMG00000016160 +94235 GNG8 HGNC:HGNC:19664|Ensembl:ENSG00000167414|Vega:OTTHUMG00000183430 +94236 DNAJA1P5 HGNC:HGNC:39341 +94239 H2AFV HGNC:HGNC:20664|Ensembl:ENSG00000105968|Vega:OTTHUMG00000129217 +94240 EPSTI1 MIM:607441|HGNC:HGNC:16465|Ensembl:ENSG00000133106|Vega:OTTHUMG00000016814 +94241 TP53INP1 MIM:606185|HGNC:HGNC:18022|Ensembl:ENSG00000164938|Vega:OTTHUMG00000164697 +94274 PPP1R14A MIM:608153|HGNC:HGNC:14871|Ensembl:ENSG00000167641|Vega:OTTHUMG00000181892 +94297 PPP1R11P1 HGNC:HGNC:16326 +94298 PPP1R11P2 HGNC:HGNC:16327 +94299 TP53BP2P1 HGNC:HGNC:16328 +94302 PPP1R14BP4 HGNC:HGNC:16331 +94304 PPP1R1AP1 HGNC:HGNC:16316 +94310 PPP1R2P8 HGNC:HGNC:16323 +94313 AUTS5 MIM:606053 +94337 MNG3 MIM:606082 +95681 CEP41 MIM:610523|HGNC:HGNC:12370|Ensembl:ENSG00000106477|Vega:OTTHUMG00000157823 +96459 FNIP1 MIM:610594|HGNC:HGNC:29418|Ensembl:ENSG00000217128|Vega:OTTHUMG00000186338 +96597 TBC1D27 HGNC:HGNC:28104 +96610 BMS1P20 HGNC:HGNC:49153 +96626 LIMS3 HGNC:HGNC:30047|Ensembl:ENSG00000256977|Vega:OTTHUMG00000191772 +96764 TGS1 MIM:606461|HGNC:HGNC:17843|Ensembl:ENSG00000137574|Vega:OTTHUMG00000164294 +100917 VWSM MIM:604547 +100918 NRCLP2 MIM:605841 +103910 MYL12B MIM:609211|HGNC:HGNC:29827|Ensembl:ENSG00000118680|Vega:OTTHUMG00000131510 +103911 RPS27AP1 HGNC:HGNC:17121 +112398 EGLN2 MIM:606424|HGNC:HGNC:14660|Ensembl:ENSG00000269858|Vega:OTTHUMG00000182703 +112399 EGLN3 MIM:606426|HGNC:HGNC:14661|Ensembl:ENSG00000129521|Vega:OTTHUMG00000029498 +112401 BIRC8 HGNC:HGNC:14878|Ensembl:ENSG00000163098|Vega:OTTHUMG00000182919 +112464 CAVIN3 HGNC:HGNC:9400|Ensembl:ENSG00000170955|Vega:OTTHUMG00000133378 +112476 PRRT2 MIM:614386|HGNC:HGNC:30500|Ensembl:ENSG00000167371|Vega:OTTHUMG00000177142 +112479 ERI2 HGNC:HGNC:30541|Ensembl:ENSG00000196678|Vega:OTTHUMG00000131557 +112483 SAT2 MIM:611463|HGNC:HGNC:23160|Ensembl:ENSG00000141504|Vega:OTTHUMG00000108152 +112487 DTD2 HGNC:HGNC:20277|Ensembl:ENSG00000129480|Vega:OTTHUMG00000140205 +112495 GTF3C6 MIM:611784|HGNC:HGNC:20872|Ensembl:ENSG00000155115|Vega:OTTHUMG00000015370 +112574 SNX18 HGNC:HGNC:19245|Ensembl:ENSG00000178996|Vega:OTTHUMG00000096994 +112597 CYTOR HGNC:HGNC:28717|Ensembl:ENSG00000222041 +112609 MRAP2 MIM:615410|HGNC:HGNC:21232|Ensembl:ENSG00000135324|Vega:OTTHUMG00000015121 +112611 RWDD2A HGNC:HGNC:21385|Ensembl:ENSG00000013392|Vega:OTTHUMG00000015109 +112616 CMTM7 MIM:607890|HGNC:HGNC:19178|Ensembl:ENSG00000153551|Vega:OTTHUMG00000155869 +112703 FAM71E1 HGNC:HGNC:25107|Ensembl:ENSG00000142530|Vega:OTTHUMG00000183041 +112714 TUBA3E HGNC:HGNC:20765|Ensembl:ENSG00000152086|Vega:OTTHUMG00000131626 +112724 RDH13 HGNC:HGNC:19978|Ensembl:ENSG00000160439|Vega:OTTHUMG00000180478 +112744 IL17F MIM:606496|HGNC:HGNC:16404|Ensembl:ENSG00000112116|Vega:OTTHUMG00000014845 +112752 IFT43 MIM:614068|HGNC:HGNC:29669|Ensembl:ENSG00000119650|Vega:OTTHUMG00000171613 +112755 STX1B MIM:601485|HGNC:HGNC:18539|Ensembl:ENSG00000099365|Vega:OTTHUMG00000132391 +112770 GLMP HGNC:HGNC:29436|Ensembl:ENSG00000198715|Vega:OTTHUMG00000019789 +112802 KRT71 MIM:608245|HGNC:HGNC:28927|Ensembl:ENSG00000139648|Vega:OTTHUMG00000167831 +112812 FDX1L MIM:614585|HGNC:HGNC:30546|Ensembl:ENSG00000267673|Vega:OTTHUMG00000141299 +112817 HOGA1 MIM:613597|HGNC:HGNC:25155|Ensembl:ENSG00000241935|Vega:OTTHUMG00000018859 +112840 WDR89 HGNC:HGNC:20489|Ensembl:ENSG00000140006|Vega:OTTHUMG00000140340 +112846 RBM8B HGNC:HGNC:13426 +112849 L3HYPDH MIM:614811|HGNC:HGNC:20488|Ensembl:ENSG00000126790|Vega:OTTHUMG00000028941 +112858 TP53RK MIM:608679|HGNC:HGNC:16197|Ensembl:ENSG00000172315|Vega:OTTHUMG00000085887 +112869 SGF29 MIM:613374|HGNC:HGNC:25156|Ensembl:ENSG00000176476|Vega:OTTHUMG00000131763 +112885 PHF21B MIM:616727|HGNC:HGNC:25161|Ensembl:ENSG00000056487|Vega:OTTHUMG00000151199 +112936 VPS26B MIM:610027|HGNC:HGNC:28119|Ensembl:ENSG00000151502|Vega:OTTHUMG00000167175 +112937 GLB1L3 HGNC:HGNC:25147|Ensembl:ENSG00000166105|Vega:OTTHUMG00000133524 +112939 NACC1 MIM:610672|HGNC:HGNC:20967|Ensembl:ENSG00000160877|Vega:OTTHUMG00000180748 +112942 CFAP36 HGNC:HGNC:30540|Ensembl:ENSG00000163001|Vega:OTTHUMG00000129339 +112950 MED8 MIM:607956|HGNC:HGNC:19971|Ensembl:ENSG00000159479|Vega:OTTHUMG00000007421 +112970 KTI12 HGNC:HGNC:25160|Ensembl:ENSG00000198841|Vega:OTTHUMG00000008630 +113000 RPUSD1 HGNC:HGNC:14173|Ensembl:ENSG00000007376|Vega:OTTHUMG00000047840 +113026 PLCD3 MIM:608795|HGNC:HGNC:9061|Ensembl:ENSG00000161714|Vega:OTTHUMG00000168029 +113091 PTH2 MIM:608386|HGNC:HGNC:30828|Ensembl:ENSG00000142538|Vega:OTTHUMG00000183165 +113115 MTFR2 HGNC:HGNC:21115|Ensembl:ENSG00000146410|Vega:OTTHUMG00000015643 +113130 CDCA5 MIM:609374|HGNC:HGNC:14626|Ensembl:ENSG00000146670|Vega:OTTHUMG00000150420 +113146 AHNAK2 MIM:608570|HGNC:HGNC:20125|Ensembl:ENSG00000185567|Vega:OTTHUMG00000170765 +113157 RPLP0P2 HGNC:HGNC:17960|Ensembl:ENSG00000243742 +113174 SAAL1 HGNC:HGNC:25158|Ensembl:ENSG00000166788|Vega:OTTHUMG00000166428 +113177 IZUMO4 HGNC:HGNC:26950|Ensembl:ENSG00000099840|Vega:OTTHUMG00000141290 +113178 SCAMP4 MIM:613764|HGNC:HGNC:30385|Ensembl:ENSG00000227500|Vega:OTTHUMG00000154590 +113179 ADAT3 MIM:615302|HGNC:HGNC:25151|Ensembl:ENSG00000213638|Vega:OTTHUMG00000154591 +113189 CHST14 MIM:608429|HGNC:HGNC:24464|Ensembl:ENSG00000169105|Vega:OTTHUMG00000129985 +113201 CASC4 HGNC:HGNC:24892|Ensembl:ENSG00000166734|Vega:OTTHUMG00000131133 +113220 KIF12 MIM:611278|HGNC:HGNC:21495|Ensembl:ENSG00000136883|Vega:OTTHUMG00000020533 +113230 MISP3 HGNC:HGNC:26963|Ensembl:ENSG00000141854|Vega:OTTHUMG00000181994 +113235 SLC46A1 MIM:611672|HGNC:HGNC:30521|Ensembl:ENSG00000076351|Vega:OTTHUMG00000179415 +113246 C12orf57 MIM:615140|HGNC:HGNC:29521|Ensembl:ENSG00000111678|Vega:OTTHUMG00000169017 +113251 LARP4 HGNC:HGNC:24320|Ensembl:ENSG00000161813|Vega:OTTHUMG00000163724 +113263 GLCCI1 MIM:614283|HGNC:HGNC:18713|Ensembl:ENSG00000106415|Vega:OTTHUMG00000151984 +113277 TMEM106A HGNC:HGNC:28288|Ensembl:ENSG00000184988|Vega:OTTHUMG00000180879 +113278 SLC52A3 MIM:613350|HGNC:HGNC:16187|Ensembl:ENSG00000101276|Vega:OTTHUMG00000031647 +113402 SFT2D1 HGNC:HGNC:21102|Ensembl:ENSG00000198818|Vega:OTTHUMG00000016001 +113419 TEX261 HGNC:HGNC:30712|Ensembl:ENSG00000144043|Vega:OTTHUMG00000170601 +113444 SMIM12 HGNC:HGNC:25154|Ensembl:ENSG00000163866|Vega:OTTHUMG00000004375 +113451 AZIN2 MIM:608353|HGNC:HGNC:29957|Ensembl:ENSG00000142920|Vega:OTTHUMG00000004130 +113452 TMEM54 HGNC:HGNC:24143|Ensembl:ENSG00000121900|Vega:OTTHUMG00000004016 +113457 TUBA3D HGNC:HGNC:24071|Ensembl:ENSG00000075886|Vega:OTTHUMG00000153600 +113510 HELQ MIM:606769|HGNC:HGNC:18536|Ensembl:ENSG00000163312|Vega:OTTHUMG00000130423 +113540 CMTM1 MIM:607884|HGNC:HGNC:19172|Ensembl:ENSG00000089505|Vega:OTTHUMG00000137502 +113612 CYP2U1 MIM:610670|HGNC:HGNC:20582|Ensembl:ENSG00000155016|Vega:OTTHUMG00000161084 +113622 ADPRHL1 MIM:610620|HGNC:HGNC:21303|Ensembl:ENSG00000153531|Vega:OTTHUMG00000017386 +113655 MFSD3 HGNC:HGNC:25157|Ensembl:ENSG00000167700|Vega:OTTHUMG00000165177 +113675 SDSL HGNC:HGNC:30404|Ensembl:ENSG00000139410|Vega:OTTHUMG00000169551 +113691 TUBA3FP HGNC:HGNC:24067|Ensembl:ENSG00000161149 +113730 KLHDC7B HGNC:HGNC:25145|Ensembl:ENSG00000130487|Vega:OTTHUMG00000150250 +113746 ODF3 MIM:608356|HGNC:HGNC:19905|Ensembl:ENSG00000177947|Vega:OTTHUMG00000119073 +113763 ZBED6CL MIM:615252|HGNC:HGNC:21720|Ensembl:ENSG00000188707|Vega:OTTHUMG00000158328 +113791 PIK3IP1 HGNC:HGNC:24942|Ensembl:ENSG00000100100|Vega:OTTHUMG00000151256 +113802 HENMT1 MIM:612178|HGNC:HGNC:26400|Ensembl:ENSG00000162639|Vega:OTTHUMG00000011123 +113828 FAM83F HGNC:HGNC:25148|Ensembl:ENSG00000133477|Vega:OTTHUMG00000150688 +113829 SLC35A4 HGNC:HGNC:20753|Ensembl:ENSG00000176087|Vega:OTTHUMG00000129495 +113835 ZNF257 MIM:606957|HGNC:HGNC:13498|Ensembl:ENSG00000197134|Vega:OTTHUMG00000182927 +113877 DFNB32 MIM:608653|HGNC:HGNC:16360 +113878 DTX2 MIM:613141|HGNC:HGNC:15973|Ensembl:ENSG00000091073|Vega:OTTHUMG00000162594 +114026 ZIM3 HGNC:HGNC:16366|Ensembl:ENSG00000141946|Vega:OTTHUMG00000183102 +114034 TOE1 MIM:613931|HGNC:HGNC:15954|Ensembl:ENSG00000132773|Vega:OTTHUMG00000007678 +114036 LINC00310 HGNC:HGNC:16414|Ensembl:ENSG00000227456 +114038 LINC00313 HGNC:HGNC:16416|Ensembl:ENSG00000185186 +114041 B3GALT5-AS1 HGNC:HGNC:16424|Ensembl:ENSG00000184809 +114042 LINC00334 HGNC:HGNC:16425|Ensembl:ENSG00000182586 +114043 TSPEAR-AS2 HGNC:HGNC:16428 +114044 MCM3AP-AS1 HGNC:HGNC:16417|Ensembl:ENSG00000215424 +114049 BUD23 MIM:615733|HGNC:HGNC:16405|Ensembl:ENSG00000071462|Vega:OTTHUMG00000023306 +114086 DBA2 MIM:606129 +114088 TRIM9 MIM:606555|HGNC:HGNC:16288|Ensembl:ENSG00000100505|Vega:OTTHUMG00000140291 +114112 TXNRD3 MIM:606235|HGNC:HGNC:20667|Ensembl:ENSG00000197763|Vega:OTTHUMG00000162733 +114131 UCN3 MIM:605901|HGNC:HGNC:17781|Ensembl:ENSG00000178473|Vega:OTTHUMG00000017594 +114132 SIGLEC11 MIM:607157|HGNC:HGNC:15622|Ensembl:ENSG00000161640|Vega:OTTHUMG00000157077 +114134 SLC2A13 MIM:611036|HGNC:HGNC:15956|Ensembl:ENSG00000151229|Vega:OTTHUMG00000059743 +114181 FAM8A5P HGNC:HGNC:16376 +114182 FAM8A6P HGNC:HGNC:16377 +114184 SIGLEC18P HGNC:HGNC:15491 +114185 SIGLEC26P HGNC:HGNC:15615 +114186 SIGLEC27P HGNC:HGNC:15617 +114187 SIGLEC28P HGNC:HGNC:15618 +114188 SIGLEC29P HGNC:HGNC:15619 +114189 SIGLEC31P HGNC:HGNC:16072 +114190 SIGLEC30P HGNC:HGNC:15623 +114192 SIGLEC20P HGNC:HGNC:15609 +114194 SIGLEC21P HGNC:HGNC:15610 +114195 SIGLEC22P HGNC:HGNC:15611 +114196 SIGLEC24P HGNC:HGNC:15613 +114198 SIGLEC25P HGNC:HGNC:15614 +114224 LOC114224 - +114293 ANBC MIM:606179 +114294 LACTB MIM:608440|HGNC:HGNC:16468|Ensembl:ENSG00000103642|Vega:OTTHUMG00000132807 +114299 PALM2 HGNC:HGNC:15845|Ensembl:ENSG00000157654|Ensembl:ENSG00000243444|Vega:OTTHUMG00000020479|Vega:OTTHUMG00000156812 +114327 EFHC1 MIM:608815|HGNC:HGNC:16406|Ensembl:ENSG00000096093|Vega:OTTHUMG00000014848 +114335 CGB1 MIM:608823|HGNC:HGNC:16721|Ensembl:ENSG00000267631|Vega:OTTHUMG00000150186 +114336 CGB2 MIM:608824|HGNC:HGNC:16722|Ensembl:ENSG00000104818|Vega:OTTHUMG00000150185 +114475 AD7 MIM:606187 +114477 ATOD6 MIM:605845 +114548 NLRP3 MIM:606416|HGNC:HGNC:16400|Ensembl:ENSG00000162711|Vega:OTTHUMG00000040647 +114568 NMTC1 MIM:606240 +114569 MAL2 MIM:609684|HGNC:HGNC:13634|Ensembl:ENSG00000147676|Vega:OTTHUMG00000164973 +114571 SLC22A9 MIM:607579|HGNC:HGNC:16261|Ensembl:ENSG00000149742|Vega:OTTHUMG00000167805 +114599 SNORD15B HGNC:HGNC:16649|Ensembl:ENSG00000207445 +114609 TIRAP MIM:606252|HGNC:HGNC:17192|Ensembl:ENSG00000150455|Vega:OTTHUMG00000140373 +114610 SAX1 MIM:108600|HGNC:HGNC:16474 +114614 MIR155HG HGNC:HGNC:35460|Ensembl:ENSG00000234883 +114625 ERMAP MIM:609017|HGNC:HGNC:15743|Ensembl:ENSG00000164010|Vega:OTTHUMG00000007619 +114655 SNORD73B HGNC:HGNC:30357 +114657 COX7BP1 HGNC:HGNC:16529 +114659 LRRC37B MIM:616558|HGNC:HGNC:29070|Ensembl:ENSG00000185158|Vega:OTTHUMG00000132785 +114757 CYGB MIM:608759|HGNC:HGNC:16505|Ensembl:ENSG00000161544|Vega:OTTHUMG00000180289 +114758 CSPG4P1Y MIM:400034|HGNC:HGNC:16478|Ensembl:ENSG00000240450 +114760 TTTY3 MIM:400036|HGNC:HGNC:16480|Ensembl:ENSG00000231141 +114761 TTTY4 MIM:400037|HGNC:HGNC:16481|Ensembl:ENSG00000226906 +114769 CARD16 MIM:615680|HGNC:HGNC:33701|Ensembl:ENSG00000204397|Vega:OTTHUMG00000166157 +114770 PGLYRP2 MIM:608199|HGNC:HGNC:30013|Ensembl:ENSG00000161031|Vega:OTTHUMG00000150690 +114771 PGLYRP3 MIM:608197|HGNC:HGNC:30014|Ensembl:ENSG00000159527|Vega:OTTHUMG00000014044 +114780 PKD1L2 MIM:607894|HGNC:HGNC:21715|Ensembl:ENSG00000166473|Vega:OTTHUMG00000166126 +114781 BTBD9 MIM:611237|HGNC:HGNC:21228|Ensembl:ENSG00000183826|Vega:OTTHUMG00000014634 +114783 LMTK3 HGNC:HGNC:19295|Ensembl:ENSG00000142235|Vega:OTTHUMG00000183312 +114784 CSMD2 MIM:608398|HGNC:HGNC:19290|Ensembl:ENSG00000121904|Vega:OTTHUMG00000011135 +114785 MBD6 HGNC:HGNC:20445|Ensembl:ENSG00000166987|Vega:OTTHUMG00000170099 +114786 XKR4 HGNC:HGNC:29394|Ensembl:ENSG00000206579|Vega:OTTHUMG00000164288 +114787 GPRIN1 MIM:611239|HGNC:HGNC:24835|Ensembl:ENSG00000169258|Vega:OTTHUMG00000130659 +114788 CSMD3 MIM:608399|HGNC:HGNC:19291|Ensembl:ENSG00000164796|Vega:OTTHUMG00000157027 +114789 SLC25A25 MIM:608745|HGNC:HGNC:20663|Ensembl:ENSG00000148339|Vega:OTTHUMG00000020736 +114790 STK11IP MIM:607172|HGNC:HGNC:19184|Ensembl:ENSG00000144589|Vega:OTTHUMG00000059239 +114791 TUBGCP5 MIM:608147|HGNC:HGNC:18600|Ensembl:ENSG00000275835|Vega:OTTHUMG00000188371 +114792 KLHL32 HGNC:HGNC:21221|Ensembl:ENSG00000186231|Vega:OTTHUMG00000015247 +114793 FMNL2 MIM:616285|HGNC:HGNC:18267|Ensembl:ENSG00000157827|Vega:OTTHUMG00000154035 +114794 ELFN2 HGNC:HGNC:29396|Ensembl:ENSG00000166897|Ensembl:ENSG00000243902|Vega:OTTHUMG00000150558 +114795 TMEM132B HGNC:HGNC:29397|Ensembl:ENSG00000139364|Vega:OTTHUMG00000168520 +114796 PSMG3-AS1 HGNC:HGNC:22230|Ensembl:ENSG00000230487 +114798 SLITRK1 MIM:609678|HGNC:HGNC:20297|Ensembl:ENSG00000178235|Vega:OTTHUMG00000017149 +114799 ESCO1 MIM:609674|HGNC:HGNC:24645|Ensembl:ENSG00000141446|Vega:OTTHUMG00000178919 +114800 CCDC85A HGNC:HGNC:29400|Ensembl:ENSG00000055813|Vega:OTTHUMG00000152033 +114801 TMEM200A HGNC:HGNC:21075|Ensembl:ENSG00000164484|Vega:OTTHUMG00000015557 +114803 MYSM1 MIM:612176|HGNC:HGNC:29401|Ensembl:ENSG00000162601|Vega:OTTHUMG00000009533 +114804 RNF157 HGNC:HGNC:29402|Ensembl:ENSG00000141576|Vega:OTTHUMG00000132627 +114805 GALNT13 MIM:608369|HGNC:HGNC:23242|Ensembl:ENSG00000144278|Vega:OTTHUMG00000131917 +114814 GNRHR2 MIM:612875|HGNC:HGNC:16341|Ensembl:ENSG00000211451 +114815 SORCS1 MIM:606283|HGNC:HGNC:16697|Ensembl:ENSG00000108018|Vega:OTTHUMG00000019018 +114817 CSPG4P5 HGNC:HGNC:29403 +114818 KLHL29 HGNC:HGNC:29404|Ensembl:ENSG00000119771|Vega:OTTHUMG00000151899 +114819 CROCCP3 HGNC:HGNC:29405|Ensembl:ENSG00000080947 +114821 ZBED9 MIM:615254|HGNC:HGNC:13851|Ensembl:ENSG00000232040|Vega:OTTHUMG00000016237 +114822 RHPN1 MIM:601031|HGNC:HGNC:19973|Ensembl:ENSG00000158106|Vega:OTTHUMG00000165006 +114823 LENG8 MIM:616575|HGNC:HGNC:15500|Ensembl:ENSG00000167615|Vega:OTTHUMG00000065548 +114824 PNMA5 MIM:300916|HGNC:HGNC:18743|Ensembl:ENSG00000198883|Vega:OTTHUMG00000024184 +114825 PWWP2A HGNC:HGNC:29406|Ensembl:ENSG00000170234|Vega:OTTHUMG00000163546 +114826 SMYD4 HGNC:HGNC:21067|Ensembl:ENSG00000186532|Vega:OTTHUMG00000090570 +114827 FHAD1 HGNC:HGNC:29408|Ensembl:ENSG00000142621|Vega:OTTHUMG00000002088 +114836 SLAMF6 MIM:606446|HGNC:HGNC:21392|Ensembl:ENSG00000162739|Vega:OTTHUMG00000022729 +114876 OSBPL1A MIM:606730|HGNC:HGNC:16398|Ensembl:ENSG00000141447|Vega:OTTHUMG00000131944 +114879 OSBPL5 MIM:606733|HGNC:HGNC:16392|Ensembl:ENSG00000021762|Vega:OTTHUMG00000011702 +114880 OSBPL6 MIM:606734|HGNC:HGNC:16388|Ensembl:ENSG00000079156|Vega:OTTHUMG00000132579 +114881 OSBPL7 MIM:606735|HGNC:HGNC:16387|Ensembl:ENSG00000006025|Vega:OTTHUMG00000178288 +114882 OSBPL8 MIM:606736|HGNC:HGNC:16396|Ensembl:ENSG00000091039|Vega:OTTHUMG00000169876 +114883 OSBPL9 MIM:606737|HGNC:HGNC:16386|Ensembl:ENSG00000117859|Vega:OTTHUMG00000008234 +114884 OSBPL10 MIM:606738|HGNC:HGNC:16395|Ensembl:ENSG00000144645|Vega:OTTHUMG00000130672 +114885 OSBPL11 MIM:606739|HGNC:HGNC:16397|Ensembl:ENSG00000144909|Vega:OTTHUMG00000159571 +114890 MRSS MIM:300360 +114897 C1QTNF1 MIM:610365|HGNC:HGNC:14324|Ensembl:ENSG00000173918|Vega:OTTHUMG00000177533 +114898 C1QTNF2 HGNC:HGNC:14325|Ensembl:ENSG00000145861|Vega:OTTHUMG00000130323 +114899 C1QTNF3 MIM:612045|HGNC:HGNC:14326|Ensembl:ENSG00000082196|Vega:OTTHUMG00000090735 +114900 C1QTNF4 MIM:614911|HGNC:HGNC:14346|Ensembl:ENSG00000172247|Vega:OTTHUMG00000166895 +114902 C1QTNF5 MIM:608752|HGNC:HGNC:14344|Ensembl:ENSG00000223953|Vega:OTTHUMG00000166198 +114904 C1QTNF6 MIM:614910|HGNC:HGNC:14343|Ensembl:ENSG00000133466|Vega:OTTHUMG00000150538 +114905 C1QTNF7 HGNC:HGNC:14342|Ensembl:ENSG00000163145|Vega:OTTHUMG00000097095 +114907 FBXO32 MIM:606604|HGNC:HGNC:16731|Ensembl:ENSG00000156804|Vega:OTTHUMG00000164981 +114908 TMEM123 MIM:606356|HGNC:HGNC:30138|Ensembl:ENSG00000152558|Vega:OTTHUMG00000167326 +114915 EPB41L4A-AS1 HGNC:HGNC:30749 +114926 SMIM19 HGNC:HGNC:25166|Ensembl:ENSG00000176209|Vega:OTTHUMG00000157060 +114928 GPRASP2 MIM:300969|HGNC:HGNC:25169|Ensembl:ENSG00000158301|Vega:OTTHUMG00000185178 +114932 MRFAP1L1 HGNC:HGNC:28796|Ensembl:ENSG00000178988|Vega:OTTHUMG00000125507 +114960 TSGA13 HGNC:HGNC:12369|Ensembl:ENSG00000213265|Vega:OTTHUMG00000154999 +114971 PTPMT1 MIM:609538|HGNC:HGNC:26965|Ensembl:ENSG00000110536|Vega:OTTHUMG00000166892 +114984 FLYWCH2 HGNC:HGNC:25178|Ensembl:ENSG00000162076|Vega:OTTHUMG00000128962 +114987 WDR31 HGNC:HGNC:21421|Ensembl:ENSG00000148225|Vega:OTTHUMG00000020525 +114990 VASN MIM:608843|HGNC:HGNC:18517|Ensembl:ENSG00000168140|Vega:OTTHUMG00000129469 +114991 ZNF618 MIM:617077|HGNC:HGNC:29416|Ensembl:ENSG00000157657|Vega:OTTHUMG00000020532 +115004 MB21D1 MIM:613973|HGNC:HGNC:21367|Ensembl:ENSG00000164430|Vega:OTTHUMG00000015034 +115019 SLC26A9 MIM:608481|HGNC:HGNC:14469|Ensembl:ENSG00000174502|Vega:OTTHUMG00000036001 +115024 NT5C3B HGNC:HGNC:28300|Ensembl:ENSG00000141698|Vega:OTTHUMG00000133499 +115098 CCDC124 HGNC:HGNC:25171|Ensembl:ENSG00000007080|Vega:OTTHUMG00000183405 +115106 HAUS1 MIM:608775|HGNC:HGNC:25174|Ensembl:ENSG00000152240|Vega:OTTHUMG00000132638 +115110 TNFRSF14-AS1 HGNC:HGNC:26966 +115111 SLC26A7 MIM:608479|HGNC:HGNC:14467|Ensembl:ENSG00000147606|Vega:OTTHUMG00000164062 +115123 MARCH3 MIM:613333|HGNC:HGNC:28728|Ensembl:ENSG00000173926|Vega:OTTHUMG00000128968 +115196 ZNF554 HGNC:HGNC:26629|Ensembl:ENSG00000172006|Vega:OTTHUMG00000180493 +115201 ATG4A MIM:300663|HGNC:HGNC:16489|Ensembl:ENSG00000101844|Vega:OTTHUMG00000022176 +115207 KCTD12 MIM:610521|HGNC:HGNC:14678|Ensembl:ENSG00000178695|Vega:OTTHUMG00000017096 +115209 OMA1 MIM:617081|HGNC:HGNC:29661|Ensembl:ENSG00000162600|Vega:OTTHUMG00000010068 +115265 DDIT4L MIM:607730|HGNC:HGNC:30555|Ensembl:ENSG00000145358|Vega:OTTHUMG00000161019 +115273 RAB42 HGNC:HGNC:28702|Ensembl:ENSG00000188060|Vega:OTTHUMG00000003656 +115286 SLC25A26 MIM:611037|HGNC:HGNC:20661|Ensembl:ENSG00000144741 +115290 FBXO17 MIM:609094|HGNC:HGNC:18754|Ensembl:ENSG00000269190 +115294 PCMTD1 HGNC:HGNC:30483|Ensembl:ENSG00000168300|Vega:OTTHUMG00000164246 +115330 GPR146 HGNC:HGNC:21718|Ensembl:ENSG00000164849|Vega:OTTHUMG00000023934 +115350 FCRL1 MIM:606508|HGNC:HGNC:18509|Ensembl:ENSG00000163534|Vega:OTTHUMG00000019398 +115352 FCRL3 MIM:606510|HGNC:HGNC:18506|Ensembl:ENSG00000160856|Vega:OTTHUMG00000019400 +115353 LRRC42 HGNC:HGNC:28792|Ensembl:ENSG00000116212|Vega:OTTHUMG00000008436 +115361 GBP4 MIM:612466|HGNC:HGNC:20480|Ensembl:ENSG00000162654|Vega:OTTHUMG00000010663 +115362 GBP5 MIM:611467|HGNC:HGNC:19895|Ensembl:ENSG00000154451|Vega:OTTHUMG00000010006 +115399 LRRC56 HGNC:HGNC:25430|Ensembl:ENSG00000161328|Vega:OTTHUMG00000132003 +115416 MALSU1 MIM:614624|HGNC:HGNC:21721|Ensembl:ENSG00000156928|Vega:OTTHUMG00000128443 +115426 UHRF2 MIM:615211|HGNC:HGNC:12557|Ensembl:ENSG00000147854|Vega:OTTHUMG00000019521 +115509 ZNF689 HGNC:HGNC:25173|Ensembl:ENSG00000156853|Vega:OTTHUMG00000132415 +115548 FCHO2 MIM:613438|HGNC:HGNC:25180|Ensembl:ENSG00000157107|Vega:OTTHUMG00000162413 +115557 ARHGEF25 MIM:610215|HGNC:HGNC:30275|Ensembl:ENSG00000240771|Vega:OTTHUMG00000152516 +115560 ZNF501 HGNC:HGNC:23717|Ensembl:ENSG00000186446|Vega:OTTHUMG00000133048 +115572 FAM46B HGNC:HGNC:28273|Ensembl:ENSG00000158246|Vega:OTTHUMG00000004278 +115584 SLC5A11 MIM:610238|HGNC:HGNC:23091|Ensembl:ENSG00000158865|Vega:OTTHUMG00000097003 +115650 TNFRSF13C MIM:606269|HGNC:HGNC:17755|Ensembl:ENSG00000159958|Vega:OTTHUMG00000151271 +115653 KIR3DL3 MIM:610095|HGNC:HGNC:16312|Ensembl:ENSG00000242019|Vega:OTTHUMG00000065884 +115677 NOSTRIN MIM:607496|HGNC:HGNC:20203|Ensembl:ENSG00000163072|Vega:OTTHUMG00000153990 +115701 ALPK2 HGNC:HGNC:20565|Ensembl:ENSG00000198796|Vega:OTTHUMG00000132755 +115703 ARHGAP33 MIM:614902|HGNC:HGNC:23085|Ensembl:ENSG00000004777|Vega:OTTHUMG00000182071 +115704 EVI5L HGNC:HGNC:30464|Ensembl:ENSG00000142459|Vega:OTTHUMG00000182454 +115708 TRMT61A HGNC:HGNC:23790|Ensembl:ENSG00000166166|Vega:OTTHUMG00000171762 +115727 RASGRP4 MIM:607320|HGNC:HGNC:18958|Ensembl:ENSG00000171777|Vega:OTTHUMG00000182327 +115749 C12orf56 HGNC:HGNC:26967|Ensembl:ENSG00000185306|Vega:OTTHUMG00000168782 +115752 DIS3L MIM:614183|HGNC:HGNC:28698|Ensembl:ENSG00000166938|Vega:OTTHUMG00000133181 +115761 ARL11 MIM:609351|HGNC:HGNC:24046|Ensembl:ENSG00000152213|Vega:OTTHUMG00000016919 +115795 FANCD2OS HGNC:HGNC:28623|Ensembl:ENSG00000163705|Vega:OTTHUMG00000128669 +115811 IQCD HGNC:HGNC:25168|Ensembl:ENSG00000166578|Vega:OTTHUMG00000169659 +115817 DHRS1 MIM:610410|HGNC:HGNC:16445|Ensembl:ENSG00000157379|Vega:OTTHUMG00000029333 +115825 WDFY2 MIM:610418|HGNC:HGNC:20482|Ensembl:ENSG00000139668|Vega:OTTHUMG00000017407 +115827 RAB3C MIM:612829|HGNC:HGNC:30269|Ensembl:ENSG00000152932|Vega:OTTHUMG00000097053 +115861 NXNL1 MIM:608791|HGNC:HGNC:25179|Ensembl:ENSG00000171773|Vega:OTTHUMG00000182798 +115908 CTHRC1 MIM:610635|HGNC:HGNC:18831|Ensembl:ENSG00000164932|Vega:OTTHUMG00000164887 +115939 TSR3 MIM:617058|HGNC:HGNC:14175|Ensembl:ENSG00000007520|Vega:OTTHUMG00000047834 +115948 CCDC151 MIM:615956|HGNC:HGNC:28303|Ensembl:ENSG00000198003|Vega:OTTHUMG00000182028 +115950 ZNF653 MIM:611371|HGNC:HGNC:25196|Ensembl:ENSG00000161914|Vega:OTTHUMG00000182032 +115992 RNF166 MIM:617178|HGNC:HGNC:28856|Ensembl:ENSG00000158717|Vega:OTTHUMG00000137863 +116028 RMI2 MIM:612426|HGNC:HGNC:28349|Ensembl:ENSG00000175643|Vega:OTTHUMG00000129793 +116039 OSR2 MIM:611297|HGNC:HGNC:15830|Ensembl:ENSG00000164920|Vega:OTTHUMG00000164640 +116064 LRRC58 HGNC:HGNC:26968|Ensembl:ENSG00000163428|Vega:OTTHUMG00000159407 +116068 LYSMD3 HGNC:HGNC:26969|Ensembl:ENSG00000176018|Vega:OTTHUMG00000162667 +116071 BATF2 MIM:614983|HGNC:HGNC:25163|Ensembl:ENSG00000168062|Vega:OTTHUMG00000165633 +116085 SLC22A12 MIM:607096|HGNC:HGNC:17989|Ensembl:ENSG00000197891|Vega:OTTHUMG00000045213 +116092 DNTTIP1 MIM:611388|HGNC:HGNC:16160|Ensembl:ENSG00000101457|Vega:OTTHUMG00000032610 +116093 DIRC1 MIM:606423|HGNC:HGNC:15760|Ensembl:ENSG00000174325|Vega:OTTHUMG00000132646 +116113 FOXP4 MIM:608924|HGNC:HGNC:20842|Ensembl:ENSG00000137166|Vega:OTTHUMG00000014679 +116115 ZNF526 MIM:614387|HGNC:HGNC:29415|Ensembl:ENSG00000167625|Vega:OTTHUMG00000182785 +116123 FMO9P HGNC:HGNC:32210|Ensembl:ENSG00000215834 +116135 LRRC3B HGNC:HGNC:28105|Ensembl:ENSG00000179796|Vega:OTTHUMG00000130572 +116138 KLHDC3 MIM:611248|HGNC:HGNC:20704|Ensembl:ENSG00000124702|Vega:OTTHUMG00000014714 +116143 WDR92 MIM:610729|HGNC:HGNC:25176|Ensembl:ENSG00000243667|Vega:OTTHUMG00000152561 +116149 RPL12P4 HGNC:HGNC:16587 +116150 NUS1 MIM:610463|HGNC:HGNC:21042|Ensembl:ENSG00000153989|Vega:OTTHUMG00000015458 +116151 FAM210B HGNC:HGNC:16102|Ensembl:ENSG00000124098|Vega:OTTHUMG00000032793 +116154 PHACTR3 MIM:608725|HGNC:HGNC:15833|Ensembl:ENSG00000087495|Vega:OTTHUMG00000032869 +116159 CYYR1 MIM:616020|HGNC:HGNC:16274|Ensembl:ENSG00000166265|Vega:OTTHUMG00000078689 +116173 CMTM5 MIM:607888|HGNC:HGNC:19176|Ensembl:ENSG00000166091|Vega:OTTHUMG00000028751 +116179 TGM7 MIM:606776|HGNC:HGNC:30790|Ensembl:ENSG00000159495|Vega:OTTHUMG00000176547 +116211 TM4SF19 HGNC:HGNC:25167|Ensembl:ENSG00000145107|Ensembl:ENSG00000273331|Vega:OTTHUMG00000155675|Vega:OTTHUMG00000186464 +116224 FAM122A MIM:617249|HGNC:HGNC:23490|Ensembl:ENSG00000187866|Vega:OTTHUMG00000019971 +116225 ZMYND19 MIM:611424|HGNC:HGNC:21146|Ensembl:ENSG00000165724|Vega:OTTHUMG00000020992 +116228 COX20 MIM:614698|HGNC:HGNC:26970|Ensembl:ENSG00000203667|Vega:OTTHUMG00000040401 +116236 ABHD15 HGNC:HGNC:26971|Ensembl:ENSG00000168792|Vega:OTTHUMG00000179721 +116238 TLCD1 HGNC:HGNC:25177|Ensembl:ENSG00000160606|Vega:OTTHUMG00000132683 +116254 GINM1 HGNC:HGNC:21074|Ensembl:ENSG00000055211|Vega:OTTHUMG00000015789 +116255 MOGAT1 MIM:610268|HGNC:HGNC:18210|Ensembl:ENSG00000124003|Vega:OTTHUMG00000153394 +116285 ACSM1 MIM:614357|HGNC:HGNC:18049|Ensembl:ENSG00000166743|Vega:OTTHUMG00000131550 +116328 C8orf34 HGNC:HGNC:30905|Ensembl:ENSG00000165084|Vega:OTTHUMG00000164438 +116337 PANX3 MIM:608422|HGNC:HGNC:20573|Ensembl:ENSG00000154143|Vega:OTTHUMG00000165925 +116349 EXOC3-AS1 HGNC:HGNC:25175|Ensembl:ENSG00000221990 +116362 RBP7 MIM:608604|HGNC:HGNC:30316|Ensembl:ENSG00000162444|Vega:OTTHUMG00000001798 +116369 SLC26A8 MIM:608480|HGNC:HGNC:14468|Ensembl:ENSG00000112053|Vega:OTTHUMG00000014586 +116372 LYPD1 MIM:610450|HGNC:HGNC:28431|Ensembl:ENSG00000150551|Vega:OTTHUMG00000153609 +116379 IL22RA2 MIM:606648|HGNC:HGNC:14901|Ensembl:ENSG00000164485|Vega:OTTHUMG00000015655 +116412 ZNF837 HGNC:HGNC:25164|Ensembl:ENSG00000152475|Vega:OTTHUMG00000183517 +116437 LINC01257 HGNC:HGNC:26972|Ensembl:ENSG00000204603 +116441 TM4SF18 HGNC:HGNC:25181|Ensembl:ENSG00000163762|Vega:OTTHUMG00000159582 +116442 RAB39B MIM:300774|HGNC:HGNC:16499|Ensembl:ENSG00000155961|Vega:OTTHUMG00000022659 +116443 GRIN3A MIM:606650|HGNC:HGNC:16767|Ensembl:ENSG00000198785|Vega:OTTHUMG00000020387 +116444 GRIN3B MIM:606651|HGNC:HGNC:16768|Ensembl:ENSG00000116032|Vega:OTTHUMG00000181904 +116447 TOP1MT MIM:606387|HGNC:HGNC:29787|Ensembl:ENSG00000184428|Vega:OTTHUMG00000164979 +116448 OLIG1 MIM:606385|HGNC:HGNC:16983|Ensembl:ENSG00000184221|Vega:OTTHUMG00000065064 +116449 CLNK MIM:611434|HGNC:HGNC:17438|Ensembl:ENSG00000109684|Vega:OTTHUMG00000160062 +116461 TSEN15 MIM:608756|HGNC:HGNC:16791|Ensembl:ENSG00000198860|Vega:OTTHUMG00000035461 +116496 FAM129A HGNC:HGNC:16784|Ensembl:ENSG00000135842|Vega:OTTHUMG00000035388 +116511 MAS1L MIM:607235|HGNC:HGNC:13961|Ensembl:ENSG00000204687|Vega:OTTHUMG00000031089 +116512 MRGPRD MIM:607231|HGNC:HGNC:29626|Ensembl:ENSG00000172938|Vega:OTTHUMG00000167896 +116519 APOA5 MIM:606368|HGNC:HGNC:17288|Ensembl:ENSG00000110243|Vega:OTTHUMG00000046116 +116534 MRGPRE MIM:607232|HGNC:HGNC:30694|Ensembl:ENSG00000184350|Vega:OTTHUMG00000011708 +116535 MRGPRF MIM:607233|HGNC:HGNC:24828|Ensembl:ENSG00000172935|Vega:OTTHUMG00000167897 +116540 MRPL53 MIM:611857|HGNC:HGNC:16684|Ensembl:ENSG00000204822|Vega:OTTHUMG00000129961 +116541 MRPL54 MIM:611858|HGNC:HGNC:16685|Ensembl:ENSG00000183617|Vega:OTTHUMG00000180873 +116629 HTX3 MIM:606325 +116710 FRA18C HGNC:HGNC:16929 +116729 PPP1R27 HGNC:HGNC:16813|Ensembl:ENSG00000182676|Vega:OTTHUMG00000177916 +116730 RPL37P2 HGNC:HGNC:17092 +116809 RPL38P1 HGNC:HGNC:17093 +116828 N4BP2L2-IT2 HGNC:HGNC:25038|Ensembl:ENSG00000281026 +116832 RPL39L MIM:607547|HGNC:HGNC:17094|Ensembl:ENSG00000163923|Vega:OTTHUMG00000156465 +116833 ANIB1 MIM:105800|HGNC:HGNC:17627 +116835 HSPA12B MIM:610702|HGNC:HGNC:16193|Ensembl:ENSG00000132622|Vega:OTTHUMG00000031755 +116840 CNTROB MIM:611425|HGNC:HGNC:29616|Ensembl:ENSG00000170037|Vega:OTTHUMG00000172932 +116841 SNAP47 HGNC:HGNC:30669|Ensembl:ENSG00000143740|Vega:OTTHUMG00000037697 +116842 LEAP2 MIM:611373|HGNC:HGNC:29571|Ensembl:ENSG00000164406|Vega:OTTHUMG00000059837 +116843 SLC18B1 MIM:613361|HGNC:HGNC:21573|Ensembl:ENSG00000146409|Vega:OTTHUMG00000015595 +116844 LRG1 MIM:611289|HGNC:HGNC:29480|Ensembl:ENSG00000171236|Vega:OTTHUMG00000182010 +116931 MED12L MIM:611318|HGNC:HGNC:16050|Ensembl:ENSG00000144893|Vega:OTTHUMG00000159844 +116933 CLRN1-AS1 HGNC:HGNC:30895|Ensembl:ENSG00000239265 +116935 RPL3P2 HGNC:HGNC:17834 +116936 SNORD139 MIM:611069|HGNC:HGNC:50421 +116937 SNORD83A MIM:611070|HGNC:HGNC:17131|Ensembl:ENSG00000209482 +116938 SNORD83B MIM:611071|HGNC:HGNC:17132|Ensembl:ENSG00000209480 +116966 WDR17 MIM:609005|HGNC:HGNC:16661|Ensembl:ENSG00000150627|Vega:OTTHUMG00000160791 +116969 ART5 MIM:610625|HGNC:HGNC:24049|Ensembl:ENSG00000167311|Vega:OTTHUMG00000011842 +116983 ACAP3 HGNC:HGNC:16754|Ensembl:ENSG00000131584|Vega:OTTHUMG00000002235 +116984 ARAP2 MIM:606645|HGNC:HGNC:16924|Ensembl:ENSG00000047365|Vega:OTTHUMG00000097811 +116985 ARAP1 MIM:606646|HGNC:HGNC:16925|Ensembl:ENSG00000186635|Vega:OTTHUMG00000157102 +116986 AGAP2 MIM:605476|HGNC:HGNC:16921|Ensembl:ENSG00000135439|Vega:OTTHUMG00000170285 +116987 AGAP1 MIM:608651|HGNC:HGNC:16922|Ensembl:ENSG00000157985|Vega:OTTHUMG00000133293 +116988 AGAP3 MIM:616813|HGNC:HGNC:16923|Ensembl:ENSG00000133612|Vega:OTTHUMG00000158724 +117084 CANDF1 MIM:114580 +117143 TADA1 MIM:612763|HGNC:HGNC:30631|Ensembl:ENSG00000152382|Vega:OTTHUMG00000034321 +117144 CATSPER1 MIM:606389|HGNC:HGNC:17116|Ensembl:ENSG00000175294|Vega:OTTHUMG00000166668 +117145 THEM4 MIM:606388|HGNC:HGNC:17947|Ensembl:ENSG00000159445|Vega:OTTHUMG00000013049 +117151 SLC31A1P1 HGNC:HGNC:17124 +117154 DACH2 MIM:300608|HGNC:HGNC:16814|Ensembl:ENSG00000126733|Vega:OTTHUMG00000021944 +117155 CATSPER2 MIM:607249|HGNC:HGNC:18810|Ensembl:ENSG00000166762|Vega:OTTHUMG00000059902 +117156 SCGB3A2 MIM:606531|HGNC:HGNC:18391|Ensembl:ENSG00000164265|Vega:OTTHUMG00000129729 +117157 SH2D1B MIM:608510|HGNC:HGNC:30416|Ensembl:ENSG00000198574|Vega:OTTHUMG00000031377 +117159 DCD MIM:606634|HGNC:HGNC:14669|Ensembl:ENSG00000161634|Vega:OTTHUMG00000169937 +117166 WFIKKN1 MIM:608021|HGNC:HGNC:30912|Ensembl:ENSG00000127578|Vega:OTTHUMG00000090359 +117177 RAB3IP MIM:608686|HGNC:HGNC:16508|Ensembl:ENSG00000127328|Vega:OTTHUMG00000169437 +117178 SSX2IP MIM:608690|HGNC:HGNC:16509|Ensembl:ENSG00000117155|Vega:OTTHUMG00000009926 +117187 ATOD3 MIM:605804 +117188 ATOD5 MIM:605844 +117189 GRDX MIM:300351 +117190 HPE6 MIM:605934 +117191 HYT1 MIM:603918 +117192 MNRI MIM:606190 +117193 THMA MIM:275220 +117194 MRGPRX2 MIM:607228|HGNC:HGNC:17983|Ensembl:ENSG00000183695|Vega:OTTHUMG00000166098 +117195 MRGPRX3 MIM:607229|HGNC:HGNC:17980|Ensembl:ENSG00000179826|Vega:OTTHUMG00000166435 +117196 MRGPRX4 MIM:607230|HGNC:HGNC:17617|Ensembl:ENSG00000179817|Vega:OTTHUMG00000166442 +117237 SXI2 MIM:300179 +117245 HRASLS5 MIM:611474|HGNC:HGNC:24978|Ensembl:ENSG00000168004|Vega:OTTHUMG00000167806 +117246 FTSJ3 HGNC:HGNC:17136|Ensembl:ENSG00000108592|Vega:OTTHUMG00000179012 +117247 SLC16A10 MIM:607550|HGNC:HGNC:17027|Ensembl:ENSG00000112394|Vega:OTTHUMG00000015371 +117248 GALNT15 MIM:615131|HGNC:HGNC:21531|Ensembl:ENSG00000131386|Vega:OTTHUMG00000156893 +117283 IP6K3 MIM:606993|HGNC:HGNC:17269|Ensembl:ENSG00000161896|Vega:OTTHUMG00000014531 +117285 DEFB118 MIM:607650|HGNC:HGNC:16196|Ensembl:ENSG00000131068|Vega:OTTHUMG00000032161 +117286 CIB3 MIM:610645|HGNC:HGNC:24580|Ensembl:ENSG00000141977|Vega:OTTHUMG00000182281 +117289 TAGAP MIM:609667|HGNC:HGNC:15669|Ensembl:ENSG00000164691|Vega:OTTHUMG00000015923 +117531 TMC1 MIM:606706|HGNC:HGNC:16513|Ensembl:ENSG00000165091|Vega:OTTHUMG00000020014 +117532 TMC2 MIM:606707|HGNC:HGNC:16527|Ensembl:ENSG00000149488|Vega:OTTHUMG00000031698 +117579 RLN3 MIM:606855|HGNC:HGNC:17135|Ensembl:ENSG00000171136|Vega:OTTHUMG00000181986 +117581 TWIST2 MIM:607556|HGNC:HGNC:20670|Ensembl:ENSG00000233608|Vega:OTTHUMG00000152836 +117583 PARD3B HGNC:HGNC:14446|Ensembl:ENSG00000116117|Vega:OTTHUMG00000154562 +117584 RFFL MIM:609735|HGNC:HGNC:24821|Ensembl:ENSG00000092871|Vega:OTTHUMG00000132933 +117608 ZNF354B HGNC:HGNC:17197|Ensembl:ENSG00000178338|Vega:OTTHUMG00000130896 +117854 TRIM6 MIM:607564|HGNC:HGNC:16277|Ensembl:ENSG00000121236|Vega:OTTHUMG00000150029 +118421 LINC00161 HGNC:HGNC:17138|Ensembl:ENSG00000226935 +118424 UBE2J2 HGNC:HGNC:19268|Ensembl:ENSG00000160087|Vega:OTTHUMG00000001911 +118425 PCAT4 MIM:609717|HGNC:HGNC:24853|Ensembl:ENSG00000251321 +118426 BORCS5 MIM:616598|HGNC:HGNC:17950|Ensembl:ENSG00000165714 +118427 OLFM3 MIM:607567|HGNC:HGNC:17990|Ensembl:ENSG00000118733|Vega:OTTHUMG00000010941 +118429 ANTXR2 MIM:608041|HGNC:HGNC:21732|Ensembl:ENSG00000163297|Vega:OTTHUMG00000151982 +118430 MUCL1 MIM:610857|HGNC:HGNC:30588|Ensembl:ENSG00000172551|Vega:OTTHUMG00000169815 +118432 RPL29P2 HGNC:HGNC:17334|Ensembl:ENSG00000240480 +118433 RPL23AP7 HGNC:HGNC:17336 +118442 GPR62 MIM:606917|HGNC:HGNC:13301|Ensembl:ENSG00000180929|Vega:OTTHUMG00000157367 +118460 EXOSC6 MIM:606490|HGNC:HGNC:19055|Ensembl:ENSG00000223496|Vega:OTTHUMG00000137578 +118461 C10orf71 HGNC:HGNC:26973|Ensembl:ENSG00000177354|Vega:OTTHUMG00000018190 +118471 PRAP1 MIM:609776|HGNC:HGNC:23304|Ensembl:ENSG00000165828|Vega:OTTHUMG00000019312 +118472 ZNF511 HGNC:HGNC:28445|Ensembl:ENSG00000198546|Vega:OTTHUMG00000019317 +118487 CHCHD1 MIM:608842|HGNC:HGNC:23518|Ensembl:ENSG00000172586|Vega:OTTHUMG00000018475 +118490 MSS51 MIM:614773|HGNC:HGNC:21000|Ensembl:ENSG00000166343|Vega:OTTHUMG00000018464 +118491 CFAP70 HGNC:HGNC:30726|Ensembl:ENSG00000156042 +118611 C10orf90 HGNC:HGNC:26563|Ensembl:ENSG00000154493|Vega:OTTHUMG00000019245 +118663 BTBD16 HGNC:HGNC:26340|Ensembl:ENSG00000138152|Vega:OTTHUMG00000019182 +118670 FAM24A HGNC:HGNC:23470|Ensembl:ENSG00000203795|Vega:OTTHUMG00000019193 +118672 PSTK MIM:611310|HGNC:HGNC:28578|Ensembl:ENSG00000179988|Vega:OTTHUMG00000019191 +118738 ZNF488 HGNC:HGNC:23535|Ensembl:ENSG00000265763|Vega:OTTHUMG00000188322 +118788 PIK3AP1 MIM:607942|HGNC:HGNC:30034|Ensembl:ENSG00000155629|Vega:OTTHUMG00000018838 +118812 MORN4 HGNC:HGNC:24001|Ensembl:ENSG00000171160|Vega:OTTHUMG00000018861 +118813 ZFYVE27 MIM:610243|HGNC:HGNC:26559|Ensembl:ENSG00000155256|Vega:OTTHUMG00000018867 +118856 MMP21 MIM:608416|HGNC:HGNC:14357|Ensembl:ENSG00000154485|Vega:OTTHUMG00000019235 +118881 COMTD1 HGNC:HGNC:26309|Ensembl:ENSG00000165644|Vega:OTTHUMG00000018518 +118924 FRA10AC1 MIM:608866|HGNC:HGNC:1162|Ensembl:ENSG00000148690|Vega:OTTHUMG00000018776 +118932 ANKRD22 HGNC:HGNC:28321|Ensembl:ENSG00000152766|Vega:OTTHUMG00000018699 +118945 CTSLP1 HGNC:HGNC:2539 +118980 SFXN2 MIM:615570|HGNC:HGNC:16086|Ensembl:ENSG00000156398|Vega:OTTHUMG00000018967 +118987 PDZD8 MIM:614235|HGNC:HGNC:26974|Ensembl:ENSG00000165650|Vega:OTTHUMG00000019122 +119016 AGAP4 HGNC:HGNC:23459|Ensembl:ENSG00000188234|Vega:OTTHUMG00000018088 +119032 BORCS7 MIM:616600|HGNC:HGNC:23516|Ensembl:ENSG00000166275|Ensembl:ENSG00000270316|Vega:OTTHUMG00000018975|Vega:OTTHUMG00000184175 +119180 LYZL2 MIM:612748|HGNC:HGNC:29613|Ensembl:ENSG00000151033|Vega:OTTHUMG00000017898 +119358 SNRPD2P1 HGNC:HGNC:31459 +119369 NUDT9P1 HGNC:HGNC:28523 +119385 AGAP11 HGNC:HGNC:29421 +119391 GSTO2 MIM:612314|HGNC:HGNC:23064|Ensembl:ENSG00000065621|Vega:OTTHUMG00000019006 +119392 SFR1 MIM:616527|HGNC:HGNC:29574|Ensembl:ENSG00000156384|Vega:OTTHUMG00000019000 +119395 CALHM3 HGNC:HGNC:23458|Ensembl:ENSG00000183128|Vega:OTTHUMG00000018989 +119437 CTAGE7P HGNC:HGNC:25111|Ensembl:ENSG00000233122 +119467 CLRN3 HGNC:HGNC:20795|Ensembl:ENSG00000180745|Vega:OTTHUMG00000019253 +119504 ANAPC16 MIM:613427|HGNC:HGNC:26976|Ensembl:ENSG00000166295|Vega:OTTHUMG00000018433 +119548 PNLIPRP3 HGNC:HGNC:23492|Ensembl:ENSG00000203837|Vega:OTTHUMG00000019100 +119559 SFXN4 MIM:615564|HGNC:HGNC:16088|Ensembl:ENSG00000183605|Vega:OTTHUMG00000019147 +119587 CPXM2 MIM:617348|HGNC:HGNC:26977|Ensembl:ENSG00000121898|Vega:OTTHUMG00000019206 +119678 OR52E2 HGNC:HGNC:14769|Ensembl:ENSG00000176787|Vega:OTTHUMG00000066608 +119679 OR52J3 HGNC:HGNC:14799|Ensembl:ENSG00000205495|Vega:OTTHUMG00000066600 +119682 OR51L1 HGNC:HGNC:14759|Ensembl:ENSG00000176798|Vega:OTTHUMG00000066605 +119687 OR51A7 HGNC:HGNC:15188|Ensembl:ENSG00000176895|Vega:OTTHUMG00000066502 +119692 OR51S1 HGNC:HGNC:15204|Ensembl:ENSG00000176922|Vega:OTTHUMG00000066506 +119694 OR51F2 HGNC:HGNC:15197|Ensembl:ENSG00000176925|Vega:OTTHUMG00000066508 +119695 OR52R1 HGNC:HGNC:15235|Ensembl:ENSG00000279270|Vega:OTTHUMG00000066510 +119696 OR51N1P HGNC:HGNC:14757 +119710 C11orf74 HGNC:HGNC:25142|Ensembl:ENSG00000166352|Vega:OTTHUMG00000166397 +119722 KRT18P14 HGNC:HGNC:6433 +119749 OR4C46 MIM:614273|HGNC:HGNC:31271|Ensembl:ENSG00000185926|Vega:OTTHUMG00000166705 +119750 OR4C2P HGNC:HGNC:14696 +119764 OR4X2 HGNC:HGNC:15184|Ensembl:ENSG00000172208|Vega:OTTHUMG00000165302 +119765 OR4B1 HGNC:HGNC:8290|Ensembl:ENSG00000175619|Vega:OTTHUMG00000166576 +119772 OR52M1 HGNC:HGNC:15225|Ensembl:ENSG00000197790|Vega:OTTHUMG00000165706 +119774 OR52K2 HGNC:HGNC:15223|Ensembl:ENSG00000181963|Vega:OTTHUMG00000165703 +119775 OR52P2P HGNC:HGNC:15233 +120065 OR5P2 HGNC:HGNC:14783|Ensembl:ENSG00000183303|Vega:OTTHUMG00000165668 +120066 OR5P3 HGNC:HGNC:14784|Ensembl:ENSG00000182334|Vega:OTTHUMG00000165669 +120071 LARGE2 MIM:609709|HGNC:HGNC:16522|Ensembl:ENSG00000165905|Vega:OTTHUMG00000167037 +120103 SLC36A4 MIM:613760|HGNC:HGNC:19660|Ensembl:ENSG00000180773|Vega:OTTHUMG00000167368 +120114 FAT3 MIM:612483|HGNC:HGNC:23112|Ensembl:ENSG00000165323|Vega:OTTHUMG00000154468 +120126 UBTFL2 HGNC:HGNC:35169 +120146 TRIM64 HGNC:HGNC:14663|Ensembl:ENSG00000204450|Vega:OTTHUMG00000167648 +120224 TMEM45B HGNC:HGNC:25194|Ensembl:ENSG00000151715|Vega:OTTHUMG00000165760 +120227 CYP2R1 MIM:608713|HGNC:HGNC:20580|Ensembl:ENSG00000186104|Vega:OTTHUMG00000165900 +120237 DBX1 HGNC:HGNC:33185|Ensembl:ENSG00000109851|Vega:OTTHUMG00000166043 +120318 RPS6P17 HGNC:HGNC:36669 +120321 CSNK1A1P2 HGNC:HGNC:30445 +120364 HNRNPA1P60 HGNC:HGNC:48790 +120376 COLCA2 MIM:615694|HGNC:HGNC:26978|Ensembl:ENSG00000214290|Vega:OTTHUMG00000166657 +120379 PIH1D2 HGNC:HGNC:25210|Ensembl:ENSG00000150773|Vega:OTTHUMG00000166925 +120400 NXPE1 HGNC:HGNC:28527|Ensembl:ENSG00000095110|Vega:OTTHUMG00000168284 +120406 NXPE2 HGNC:HGNC:26331|Ensembl:ENSG00000204361|Vega:OTTHUMG00000168293 +120425 JAML MIM:609770|HGNC:HGNC:19084|Ensembl:ENSG00000160593|Vega:OTTHUMG00000166965 +120449 CTBP2P6 HGNC:HGNC:45198 +120526 DNAJC24 MIM:611072|HGNC:HGNC:26979|Ensembl:ENSG00000170946|Vega:OTTHUMG00000133712 +120528 CYCSP25 HGNC:HGNC:24399 +120534 ARL14EP MIM:612295|HGNC:HGNC:26798|Ensembl:ENSG00000152219|Vega:OTTHUMG00000166154 +120586 OR8I2 HGNC:HGNC:15310|Ensembl:ENSG00000172154|Vega:OTTHUMG00000166831 +120775 OR2D3 HGNC:HGNC:15146|Ensembl:ENSG00000178358|Vega:OTTHUMG00000165742 +120776 OR2D2 MIM:608494|HGNC:HGNC:8244|Ensembl:ENSG00000166368|Vega:OTTHUMG00000165741 +120787 OR52W1 HGNC:HGNC:15239|Ensembl:ENSG00000175485|Vega:OTTHUMG00000165378 +120793 OR56A4 HGNC:HGNC:14791|Ensembl:ENSG00000183389|Vega:OTTHUMG00000165376 +120796 OR56A1 HGNC:HGNC:14781|Ensembl:ENSG00000180934|Vega:OTTHUMG00000165377 +120824 TRIM51GP HGNC:HGNC:43972 +120863 DEPDC4 HGNC:HGNC:22952|Ensembl:ENSG00000166153|Vega:OTTHUMG00000170318 +120872 RPL7P38 HGNC:HGNC:36731 +120892 LRRK2 MIM:609007|HGNC:HGNC:18618|Ensembl:ENSG00000188906|Vega:OTTHUMG00000059742 +120935 CCDC38 HGNC:HGNC:26843|Ensembl:ENSG00000165972|Vega:OTTHUMG00000170352 +120939 TMEM52B HGNC:HGNC:26438|Ensembl:ENSG00000165685|Vega:OTTHUMG00000168410 +121006 FAM186A HGNC:HGNC:26980|Ensembl:ENSG00000185958|Vega:OTTHUMG00000167889 +121014 TUBB8P5 HGNC:HGNC:42186 +121026 CYCSP30 HGNC:HGNC:24405 +121053 C12orf45 HGNC:HGNC:28628|Ensembl:ENSG00000151131|Vega:OTTHUMG00000169822 +121054 KRT18P20 HGNC:HGNC:33388 +121129 OR2AP1 HGNC:HGNC:15335|Ensembl:ENSG00000179615|Vega:OTTHUMG00000169960 +121130 OR10P1 HGNC:HGNC:15378|Ensembl:ENSG00000175398|Vega:OTTHUMG00000169961 +121131 PSMB3P1 HGNC:HGNC:20633 +121214 SDR9C7 MIM:609769|HGNC:HGNC:29958|Ensembl:ENSG00000170426|Vega:OTTHUMG00000171004 +121227 LRIG3 MIM:608870|HGNC:HGNC:30991|Ensembl:ENSG00000139263|Vega:OTTHUMG00000169940 +121256 TMEM132D MIM:611257|HGNC:HGNC:29411|Ensembl:ENSG00000151952|Vega:OTTHUMG00000168400 +121260 SLC15A4 MIM:615806|HGNC:HGNC:23090|Ensembl:ENSG00000139370|Vega:OTTHUMG00000168415 +121268 RHEBL1 HGNC:HGNC:21166|Ensembl:ENSG00000167550|Vega:OTTHUMG00000170407 +121270 OR11M1P HGNC:HGNC:15333 +121273 C12orf54 HGNC:HGNC:28553|Ensembl:ENSG00000177627|Vega:OTTHUMG00000170019 +121274 ZNF641 MIM:613906|HGNC:HGNC:31834|Ensembl:ENSG00000167528|Vega:OTTHUMG00000169906 +121275 OR10AD1 HGNC:HGNC:14819|Ensembl:ENSG00000172640|Vega:OTTHUMG00000168027 +121278 TPH2 MIM:607478|HGNC:HGNC:20692|Ensembl:ENSG00000139287|Vega:OTTHUMG00000169677 +121296 LOC121296 - +121328 GGTA2P HGNC:HGNC:4254 +121340 SP7 MIM:606633|HGNC:HGNC:17321|Ensembl:ENSG00000170374|Vega:OTTHUMG00000170031 +121355 GTSF1 MIM:617484|HGNC:HGNC:26565|Ensembl:ENSG00000170627|Vega:OTTHUMG00000169842 +121360 OR9K1P HGNC:HGNC:15338 +121364 OR10A7 HGNC:HGNC:15329|Ensembl:ENSG00000179919|Vega:OTTHUMG00000169860 +121391 KRT74 MIM:608248|HGNC:HGNC:28929|Ensembl:ENSG00000170484|Vega:OTTHUMG00000169658 +121441 NEDD1 MIM:600372|HGNC:HGNC:7723|Ensembl:ENSG00000139350|Vega:OTTHUMG00000170604 +121456 SLC9A7P1 HGNC:HGNC:32679|Ensembl:ENSG00000227825 +121457 IKBIP MIM:609861|HGNC:HGNC:26430|Ensembl:ENSG00000166130|Vega:OTTHUMG00000170213 +121498 LDHAL6CP HGNC:HGNC:39423 +121504 HIST4H4 MIM:615069|HGNC:HGNC:20510|Ensembl:ENSG00000197837|Vega:OTTHUMG00000168735 +121506 ERP27 MIM:610642|HGNC:HGNC:26495|Ensembl:ENSG00000139055|Vega:OTTHUMG00000168741 +121512 FGD4 MIM:611104|HGNC:HGNC:19125|Ensembl:ENSG00000139132|Vega:OTTHUMG00000137374 +121520 GOT2P4 HGNC:HGNC:22936 +121536 AEBP2 HGNC:HGNC:24051|Ensembl:ENSG00000139154|Vega:OTTHUMG00000168906 +121549 ASCL4 MIM:609155|HGNC:HGNC:24311|Ensembl:ENSG00000187855|Vega:OTTHUMG00000156964 +121551 BTBD11 HGNC:HGNC:23844|Ensembl:ENSG00000151136|Vega:OTTHUMG00000150413 +121599 SPIC MIM:612568|HGNC:HGNC:29549|Ensembl:ENSG00000166211|Vega:OTTHUMG00000170273 +121601 ANO4 MIM:610111|HGNC:HGNC:23837|Ensembl:ENSG00000151572|Vega:OTTHUMG00000170465 +121642 ALKBH2 MIM:610602|HGNC:HGNC:32487|Ensembl:ENSG00000189046|Vega:OTTHUMG00000169246 +121643 FOXN4 MIM:609429|HGNC:HGNC:21399|Ensembl:ENSG00000139445|Vega:OTTHUMG00000152868 +121665 SPPL3 MIM:608240|HGNC:HGNC:30424|Ensembl:ENSG00000157837|Vega:OTTHUMG00000169232 +121727 PEX12P1 HGNC:HGNC:39678 +121775 CHDM MIM:215400 +121793 TEX29 HGNC:HGNC:20370|Ensembl:ENSG00000153495|Vega:OTTHUMG00000017358 +121838 LINC00284 HGNC:HGNC:26981 +121906 PSMA6P4 HGNC:HGNC:39609 +121916 CYCSP35 HGNC:HGNC:24409 +121952 METTL21EP HGNC:HGNC:41948|Ensembl:ENSG00000250878 +121981 PPIAP26 HGNC:HGNC:39271 +122011 CSNK1A1L HGNC:HGNC:20289|Ensembl:ENSG00000180138|Vega:OTTHUMG00000016748 +122038 TOMM22P3 HGNC:HGNC:38739 +122042 RXFP2 MIM:606655|HGNC:HGNC:17318|Ensembl:ENSG00000133105|Vega:OTTHUMG00000016690 +122046 TEX26 HGNC:HGNC:28622|Ensembl:ENSG00000175664|Vega:OTTHUMG00000016682 +122060 SLAIN1 MIM:610491|HGNC:HGNC:26387|Ensembl:ENSG00000139737|Vega:OTTHUMG00000017110 +122145 RIOK3P1 HGNC:HGNC:39714 +122183 PRR20A HGNC:HGNC:24754|Ensembl:ENSG00000204919|Vega:OTTHUMG00000160602 +122199 LGMNP1 HGNC:HGNC:23079 +122258 SPACA7 HGNC:HGNC:29575|Ensembl:ENSG00000153498|Vega:OTTHUMG00000017365 +122335 PPIAP24 HGNC:HGNC:39269 +122402 TDRD9 HGNC:HGNC:20122|Ensembl:ENSG00000156414|Vega:OTTHUMG00000152876 +122409 RPL21P12 HGNC:HGNC:19810 +122416 ANKRD9 HGNC:HGNC:20096|Ensembl:ENSG00000156381|Vega:OTTHUMG00000171777 +122449 RPS29P1 HGNC:HGNC:19783 +122481 AK7 MIM:615364|HGNC:HGNC:20091|Ensembl:ENSG00000140057|Vega:OTTHUMG00000171421 +122509 IFI27L1 MIM:611320|HGNC:HGNC:19754|Ensembl:ENSG00000165948|Vega:OTTHUMG00000171302 +122525 C14orf28 HGNC:HGNC:19834|Ensembl:ENSG00000179476|Vega:OTTHUMG00000170722 +122552 PPIAP4 HGNC:HGNC:19935 +122553 TRAPPC6B MIM:610397|HGNC:HGNC:23066|Ensembl:ENSG00000182400|Vega:OTTHUMG00000140259 +122589 RPLP0P3 HGNC:HGNC:23558 +122592 KRT18P6 HGNC:HGNC:20280 +122616 CLBA1 HGNC:HGNC:20126|Ensembl:ENSG00000140104|Vega:OTTHUMG00000170474 +122618 PLD4 HGNC:HGNC:23792|Ensembl:ENSG00000166428|Vega:OTTHUMG00000144167 +122622 ADSSL1 MIM:612498|HGNC:HGNC:20093|Ensembl:ENSG00000185100|Vega:OTTHUMG00000170818 +122631 CEND1P1 HGNC:HGNC:43674 +122651 RNASE11 HGNC:HGNC:19269|Ensembl:ENSG00000173464|Vega:OTTHUMG00000170990 +122664 TPPP2 MIM:616956|HGNC:HGNC:19293|Ensembl:ENSG00000179636|Vega:OTTHUMG00000171071 +122665 RNASE8 MIM:612485|HGNC:HGNC:19277|Ensembl:ENSG00000173431|Vega:OTTHUMG00000029645 +122704 MRPL52 MIM:611856|HGNC:HGNC:16655|Ensembl:ENSG00000172590|Vega:OTTHUMG00000028703 +122706 PSMB11 MIM:611137|HGNC:HGNC:31963|Ensembl:ENSG00000222028|Vega:OTTHUMG00000170279 +122740 OR4K14 HGNC:HGNC:15352|Ensembl:ENSG00000169484|Vega:OTTHUMG00000170780 +122742 OR4L1 HGNC:HGNC:15356|Ensembl:ENSG00000176246|Vega:OTTHUMG00000169492 +122748 OR11H6 HGNC:HGNC:15349|Ensembl:ENSG00000176219|Vega:OTTHUMG00000170850 +122769 LRR1 MIM:609193|HGNC:HGNC:19742|Ensembl:ENSG00000165501|Vega:OTTHUMG00000140273 +122773 KLHDC1 MIM:611281|HGNC:HGNC:19836|Ensembl:ENSG00000197776|Vega:OTTHUMG00000140295 +122786 FRMD6 MIM:614555|HGNC:HGNC:19839|Ensembl:ENSG00000139926|Vega:OTTHUMG00000140294 +122809 SOCS4 MIM:616337|HGNC:HGNC:19392|Ensembl:ENSG00000180008|Vega:OTTHUMG00000140311 +122830 NAA30 HGNC:HGNC:19844|Ensembl:ENSG00000139977|Vega:OTTHUMG00000171311 +122837 UBA52P3 HGNC:HGNC:20056 +122842 PPIAP5 HGNC:HGNC:20027 +122867 COX4I1P1 HGNC:HGNC:2266 +122876 GPHB5 MIM:609652|HGNC:HGNC:18055|Ensembl:ENSG00000179600|Vega:OTTHUMG00000168678 +122888 PTBP1P HGNC:HGNC:20030 +122942 FXNP1 HGNC:HGNC:20012 +122945 NOXRED1 HGNC:HGNC:20487|Ensembl:ENSG00000165555|Vega:OTTHUMG00000171554 +122950 CYCSP1 HGNC:HGNC:20095 +122953 JDP2 MIM:608657|HGNC:HGNC:17546|Ensembl:ENSG00000140044|Vega:OTTHUMG00000171869 +122961 ISCA2 MIM:615317|HGNC:HGNC:19857|Ensembl:ENSG00000165898|Vega:OTTHUMG00000171214 +122970 ACOT4 MIM:614314|HGNC:HGNC:19748|Ensembl:ENSG00000177465|Vega:OTTHUMG00000169485 +123016 TTC8 MIM:608132|HGNC:HGNC:20087|Ensembl:ENSG00000165533|Vega:OTTHUMG00000170884 +123036 TC2N HGNC:HGNC:19859|Ensembl:ENSG00000165929|Vega:OTTHUMG00000171121 +123041 SLC24A4 MIM:609840|HGNC:HGNC:10978|Ensembl:ENSG00000140090|Vega:OTTHUMG00000167589 +123096 SLC25A29 MIM:615064|HGNC:HGNC:20116|Ensembl:ENSG00000197119|Vega:OTTHUMG00000171569 +123099 DEGS2 MIM:610862|HGNC:HGNC:20113|Ensembl:ENSG00000168350|Vega:OTTHUMG00000171537 +123103 KLHL33 HGNC:HGNC:31952|Ensembl:ENSG00000185271|Vega:OTTHUMG00000170982 +123169 LEO1 MIM:610507|HGNC:HGNC:30401|Ensembl:ENSG00000166477|Vega:OTTHUMG00000131843 +123207 C15orf40 HGNC:HGNC:28443|Ensembl:ENSG00000169609|Vega:OTTHUMG00000160473 +123228 SENP8 MIM:608659|HGNC:HGNC:22992|Ensembl:ENSG00000166192|Vega:OTTHUMG00000133441 +123263 MTFMT MIM:611766|HGNC:HGNC:29666|Ensembl:ENSG00000103707|Vega:OTTHUMG00000172371 +123264 SLC51B MIM:612085|HGNC:HGNC:29956|Ensembl:ENSG00000186198|Vega:OTTHUMG00000133116 +123283 TARSL2 HGNC:HGNC:24728|Ensembl:ENSG00000185418|Vega:OTTHUMG00000149869 +123346 HIGD2B HGNC:HGNC:26984|Ensembl:ENSG00000175202|Vega:OTTHUMG00000172776 +123355 LRRC28 HGNC:HGNC:28355|Ensembl:ENSG00000168904|Vega:OTTHUMG00000149854 +123591 TMEM266 HGNC:HGNC:26763|Ensembl:ENSG00000169758|Vega:OTTHUMG00000142918 +123606 NIPA1 MIM:608145|HGNC:HGNC:17043|Ensembl:ENSG00000170113|Vega:OTTHUMG00000129099 +123624 AGBL1 MIM:615496|HGNC:HGNC:26504|Ensembl:ENSG00000273540|Vega:OTTHUMG00000149978 +123688 HYKK MIM:614681|HGNC:HGNC:34403|Ensembl:ENSG00000188266|Vega:OTTHUMG00000177204 +123720 WHAMM MIM:612393|HGNC:HGNC:30493|Ensembl:ENSG00000156232|Vega:OTTHUMG00000172422 +123722 FSD2 HGNC:HGNC:18024|Ensembl:ENSG00000186628|Vega:OTTHUMG00000172400 +123745 PLA2G4E HGNC:HGNC:24791|Ensembl:ENSG00000188089|Vega:OTTHUMG00000130371 +123775 C16orf46 HGNC:HGNC:26525|Ensembl:ENSG00000166455|Vega:OTTHUMG00000137629 +123787 PRSS29P HGNC:HGNC:17542 +123803 NTAN1 MIM:615367|HGNC:HGNC:29909|Ensembl:ENSG00000157045|Vega:OTTHUMG00000129849 +123811 FOPNL MIM:617149|HGNC:HGNC:26435|Ensembl:ENSG00000133393|Vega:OTTHUMG00000129923 +123862 LOC123862 - +123872 DNAAF1 MIM:613190|HGNC:HGNC:30539|Ensembl:ENSG00000154099|Vega:OTTHUMG00000128517 +123876 ACSM2A MIM:614358|HGNC:HGNC:32017|Ensembl:ENSG00000183747|Vega:OTTHUMG00000177401 +123879 DCUN1D3 MIM:616167|HGNC:HGNC:28734|Ensembl:ENSG00000188215|Vega:OTTHUMG00000131553 +123904 NRN1L HGNC:HGNC:29811|Ensembl:ENSG00000188038|Vega:OTTHUMG00000137541 +123920 CMTM3 MIM:607886|HGNC:HGNC:19174|Ensembl:ENSG00000140931|Vega:OTTHUMG00000137503 +123970 C16orf78 HGNC:HGNC:28479|Ensembl:ENSG00000166152|Vega:OTTHUMG00000133149 +124044 SPATA2L HGNC:HGNC:28393|Ensembl:ENSG00000158792|Vega:OTTHUMG00000138047 +124045 SPATA33 MIM:615409|HGNC:HGNC:26463|Ensembl:ENSG00000167523|Vega:OTTHUMG00000138048 +124056 NOXO1 MIM:611256|HGNC:HGNC:19404|Ensembl:ENSG00000196408|Vega:OTTHUMG00000128707 +124093 CCDC78 MIM:614666|HGNC:HGNC:14153|Ensembl:ENSG00000162004|Vega:OTTHUMG00000121176 +124149 ANKRD26P1 HGNC:HGNC:32955 +124152 IQCK HGNC:HGNC:28556|Ensembl:ENSG00000174628|Vega:OTTHUMG00000131453 +124199 EEF1A1P38 HGNC:HGNC:37916 +124220 ZG16B HGNC:HGNC:30456|Ensembl:ENSG00000162078|Vega:OTTHUMG00000128933 +124221 PRSS30P HGNC:HGNC:28753|Ensembl:ENSG00000172460 +124222 PAQR4 MIM:614578|HGNC:HGNC:26386|Ensembl:ENSG00000162073|Vega:OTTHUMG00000128977 +124245 ZC3H18 HGNC:HGNC:25091|Ensembl:ENSG00000158545|Vega:OTTHUMG00000137679 +124274 GPR139 HGNC:HGNC:19995|Ensembl:ENSG00000180269|Vega:OTTHUMG00000177690 +124359 CDYL2 HGNC:HGNC:23030|Ensembl:ENSG00000166446|Vega:OTTHUMG00000177004 +124401 ANKS3 MIM:617310|HGNC:HGNC:29422|Ensembl:ENSG00000168096|Vega:OTTHUMG00000129478 +124402 UBALD1 HGNC:HGNC:29576|Ensembl:ENSG00000153443|Vega:OTTHUMG00000129472 +124404 SEPT12 MIM:611562|HGNC:HGNC:26348|Ensembl:ENSG00000140623|Vega:OTTHUMG00000129481 +124411 ZNF720 HGNC:HGNC:26987|Ensembl:ENSG00000197302|Vega:OTTHUMG00000167515 +124446 TMEM219 HGNC:HGNC:25201|Ensembl:ENSG00000149932|Vega:OTTHUMG00000177105 +124454 EARS2 MIM:612799|HGNC:HGNC:29419|Ensembl:ENSG00000103356|Vega:OTTHUMG00000177018 +124460 SNX20 MIM:613281|HGNC:HGNC:30390|Ensembl:ENSG00000167208|Vega:OTTHUMG00000133173 +124491 TMEM170A HGNC:HGNC:29577|Ensembl:ENSG00000166822|Vega:OTTHUMG00000137614 +124496 ATP5F1P7 HGNC:HGNC:39748 +124512 METTL23 MIM:615262|HGNC:HGNC:26988|Ensembl:ENSG00000181038|Vega:OTTHUMG00000180371 +124535 HSF5 HGNC:HGNC:26862|Ensembl:ENSG00000176160|Vega:OTTHUMG00000179078 +124538 OR4D2 HGNC:HGNC:8294|Ensembl:ENSG00000255713|Vega:OTTHUMG00000178801 +124540 MSI2 MIM:607897|HGNC:HGNC:18585|Ensembl:ENSG00000153944|Vega:OTTHUMG00000178398 +124565 SLC38A10 MIM:616525|HGNC:HGNC:28237|Ensembl:ENSG00000157637|Vega:OTTHUMG00000168049 +124583 CANT1 MIM:613165|HGNC:HGNC:19721|Ensembl:ENSG00000171302|Vega:OTTHUMG00000177570 +124590 USH1G MIM:607696|HGNC:HGNC:16356|Ensembl:ENSG00000182040|Vega:OTTHUMG00000178864 +124599 CD300LB MIM:610705|HGNC:HGNC:30811|Ensembl:ENSG00000178789|Vega:OTTHUMG00000067606 +124602 KIF19 HGNC:HGNC:26735|Ensembl:ENSG00000196169|Vega:OTTHUMG00000150694 +124626 ZPBP2 MIM:608499|HGNC:HGNC:20678|Ensembl:ENSG00000186075|Vega:OTTHUMG00000133022 +124637 CYB5D1 HGNC:HGNC:26516|Ensembl:ENSG00000182224|Vega:OTTHUMG00000178175 +124641 OVCA2 MIM:607896|HGNC:HGNC:24203|Ensembl:ENSG00000262664|Vega:OTTHUMG00000132471 +124685 MYL6P5 HGNC:HGNC:51646 +124739 USP43 HGNC:HGNC:20072|Ensembl:ENSG00000154914|Vega:OTTHUMG00000177942 +124751 KRBA2 HGNC:HGNC:26989|Ensembl:ENSG00000184619|Vega:OTTHUMG00000132864 +124773 C17orf64 HGNC:HGNC:26990|Ensembl:ENSG00000141371|Vega:OTTHUMG00000157171 +124783 SPATA32 HGNC:HGNC:26349|Ensembl:ENSG00000184361|Vega:OTTHUMG00000180363 +124790 HEXIM2 MIM:615695|HGNC:HGNC:28591|Ensembl:ENSG00000168517|Vega:OTTHUMG00000180193 +124801 LSM12 MIM:611793|HGNC:HGNC:26407|Ensembl:ENSG00000161654|Vega:OTTHUMG00000181804 +124808 CCDC43 HGNC:HGNC:26472|Ensembl:ENSG00000180329|Vega:OTTHUMG00000181822 +124817 CNTD1 HGNC:HGNC:26847|Ensembl:ENSG00000176563|Vega:OTTHUMG00000180652 +124842 TMEM132E MIM:616178|HGNC:HGNC:26991|Ensembl:ENSG00000181291|Vega:OTTHUMG00000132927 +124857 WFIKKN2 MIM:610895|HGNC:HGNC:30916|Ensembl:ENSG00000173714|Vega:OTTHUMG00000162274 +124865 LOC124865 - +124871 FLJ40194 Ensembl:ENSG00000177369 +124872 B4GALNT2 MIM:111730|HGNC:HGNC:24136|Ensembl:ENSG00000167080|Vega:OTTHUMG00000161307 +124912 SPACA3 MIM:612749|HGNC:HGNC:16260|Ensembl:ENSG00000141316|Vega:OTTHUMG00000132886 +124923 SGK494 Ensembl:ENSG00000167524|Vega:OTTHUMG00000179342 +124925 SEZ6 MIM:616666|HGNC:HGNC:15955|Ensembl:ENSG00000063015|Vega:OTTHUMG00000168010 +124930 ANKRD13B MIM:615124|HGNC:HGNC:26363|Ensembl:ENSG00000198720|Vega:OTTHUMG00000132731 +124935 SLC43A2 MIM:610791|HGNC:HGNC:23087|Ensembl:ENSG00000167703|Vega:OTTHUMG00000090345 +124936 CYB5D2 HGNC:HGNC:28471|Ensembl:ENSG00000167740|Vega:OTTHUMG00000177726 +124944 C17orf49 MIM:617215|HGNC:HGNC:28737|Ensembl:ENSG00000258315|Vega:OTTHUMG00000170147 +124961 ZFP3 MIM:194480|HGNC:HGNC:12861|Ensembl:ENSG00000180787|Vega:OTTHUMG00000177799 +124974 TXNP4 HGNC:HGNC:49484 +124975 GGT6 MIM:612341|HGNC:HGNC:26891|Ensembl:ENSG00000167741|Vega:OTTHUMG00000177827 +124976 SPNS2 MIM:612584|HGNC:HGNC:26992|Ensembl:ENSG00000183018|Vega:OTTHUMG00000177739 +124989 EFCAB13 HGNC:HGNC:26864|Ensembl:ENSG00000178852|Vega:OTTHUMG00000164767 +124995 MRPL10 MIM:611825|HGNC:HGNC:14055|Ensembl:ENSG00000159111|Vega:OTTHUMG00000156302 +124997 WDR81 MIM:614218|HGNC:HGNC:26600|Ensembl:ENSG00000167716|Vega:OTTHUMG00000153941 +125050 RN7SK MIM:606515|HGNC:HGNC:10037|Ensembl:ENSG00000202198|Ensembl:ENSG00000283293 +125058 TBC1D16 MIM:616637|HGNC:HGNC:28356|Ensembl:ENSG00000167291|Vega:OTTHUMG00000177489 +125061 AFMID HGNC:HGNC:20910|Ensembl:ENSG00000183077|Vega:OTTHUMG00000153957 +125111 GJD3 MIM:607425|HGNC:HGNC:19147|Ensembl:ENSG00000183153|Vega:OTTHUMG00000179634 +125113 KRT222 HGNC:HGNC:28695|Ensembl:ENSG00000213424|Ensembl:ENSG00000264058|Vega:OTTHUMG00000133374|Vega:OTTHUMG00000179656 +125115 KRT40 MIM:616679|HGNC:HGNC:26707|Ensembl:ENSG00000204889|Vega:OTTHUMG00000133596 +125144 LRRC75A-AS1 HGNC:HGNC:28619|Ensembl:ENSG00000175061 +125150 ZSWIM7 MIM:614535|HGNC:HGNC:26993|Ensembl:ENSG00000214941|Vega:OTTHUMG00000059308 +125168 RIBIN - +125170 MIEF2 MIM:615498|HGNC:HGNC:17920|Ensembl:ENSG00000177427|Vega:OTTHUMG00000059392 +125206 SLC5A10 HGNC:HGNC:23155|Ensembl:ENSG00000154025|Vega:OTTHUMG00000178143 +125208 RPS2P46 HGNC:HGNC:35839 +125228 FAM210A HGNC:HGNC:28346|Ensembl:ENSG00000177150|Vega:OTTHUMG00000131719 +125242 KRT18P8 HGNC:HGNC:31093 +125336 LOXHD1 MIM:613072|HGNC:HGNC:26521|Ensembl:ENSG00000167210|Vega:OTTHUMG00000132644 +125371 RPL22P1 HGNC:HGNC:17998 +125476 INO80C HGNC:HGNC:26994|Ensembl:ENSG00000153391|Vega:OTTHUMG00000132564 +125488 TTC39C HGNC:HGNC:26595|Ensembl:ENSG00000168234|Vega:OTTHUMG00000179403 +125704 FAM69C MIM:614544|HGNC:HGNC:31729|Ensembl:ENSG00000187773|Vega:OTTHUMG00000156984 +125875 CLDND2 HGNC:HGNC:28511|Ensembl:ENSG00000160318|Vega:OTTHUMG00000182901 +125893 ZNF816 HGNC:HGNC:26995|Ensembl:ENSG00000180257|Vega:OTTHUMG00000167761 +125919 ZNF543 MIM:616847|HGNC:HGNC:25281|Ensembl:ENSG00000178229|Vega:OTTHUMG00000183243 +125931 CEACAM20 HGNC:HGNC:24879|Ensembl:ENSG00000273777|Vega:OTTHUMG00000151532 +125950 RAVER1 MIM:609950|HGNC:HGNC:30296|Ensembl:ENSG00000161847|Vega:OTTHUMG00000180409 +125958 OR7D4 MIM:611538|HGNC:HGNC:8380|Ensembl:ENSG00000174667|Vega:OTTHUMG00000179936 +125962 OR7G1 HGNC:HGNC:8465|Ensembl:ENSG00000161807|Vega:OTTHUMG00000168067 +125963 OR1M1 HGNC:HGNC:8220|Ensembl:ENSG00000170929|Vega:OTTHUMG00000179930 +125965 COX6B2 HGNC:HGNC:24380|Ensembl:ENSG00000160471|Vega:OTTHUMG00000180774 +125972 CALR3 MIM:611414|HGNC:HGNC:20407|Ensembl:ENSG00000269058|Vega:OTTHUMG00000152571 +125981 ACER1 MIM:613491|HGNC:HGNC:18356|Ensembl:ENSG00000167769|Vega:OTTHUMG00000180777 +125988 C19orf70 MIM:616658|HGNC:HGNC:33702|Ensembl:ENSG00000174917|Vega:OTTHUMG00000180503 +125997 MBD3L2 MIM:607964|HGNC:HGNC:18532|Ensembl:ENSG00000230522|Vega:OTTHUMG00000181975 +126003 TRAPPC5 HGNC:HGNC:23067|Ensembl:ENSG00000181029|Vega:OTTHUMG00000182589 +126006 PCP2 HGNC:HGNC:30209|Ensembl:ENSG00000174788|Vega:OTTHUMG00000182405 +126014 OSCAR MIM:606862|HGNC:HGNC:29960|Ensembl:ENSG00000170909|Vega:OTTHUMG00000064966 +126017 ZNF813 HGNC:HGNC:33257|Ensembl:ENSG00000198346|Vega:OTTHUMG00000158309 +126037 EEF1DP1 HGNC:HGNC:32474 +126052 TGIF1P1 HGNC:HGNC:30730 +126068 ZNF441 HGNC:HGNC:20875|Ensembl:ENSG00000197044|Vega:OTTHUMG00000154449 +126069 ZNF491 HGNC:HGNC:23706|Ensembl:ENSG00000177599|Vega:OTTHUMG00000156529 +126070 ZNF440 HGNC:HGNC:20874|Ensembl:ENSG00000171295|Vega:OTTHUMG00000156403 +126074 SWSAP1 MIM:614536|HGNC:HGNC:26638|Ensembl:ENSG00000173928|Vega:OTTHUMG00000182025 +126075 CCDC159 HGNC:HGNC:26996|Ensembl:ENSG00000183401|Vega:OTTHUMG00000182022 +126119 JOSD2 MIM:615324|HGNC:HGNC:28853|Ensembl:ENSG00000161677|Vega:OTTHUMG00000183062 +126123 IZUMO2 HGNC:HGNC:28518|Ensembl:ENSG00000161652|Vega:OTTHUMG00000074063 +126129 CPT1C MIM:608846|HGNC:HGNC:18540|Ensembl:ENSG00000169169|Vega:OTTHUMG00000183267 +126133 ALDH16A1 MIM:613358|HGNC:HGNC:28114|Ensembl:ENSG00000161618|Vega:OTTHUMG00000183163 +126147 NTN5 HGNC:HGNC:25208|Ensembl:ENSG00000142233|Vega:OTTHUMG00000183321 +126170 LOC126170 - +126204 NLRP13 MIM:609660|HGNC:HGNC:22937|Ensembl:ENSG00000173572|Vega:OTTHUMG00000167839 +126205 NLRP8 MIM:609659|HGNC:HGNC:22940|Ensembl:ENSG00000179709|Vega:OTTHUMG00000181754 +126206 NLRP5 MIM:609658|HGNC:HGNC:21269|Ensembl:ENSG00000171487|Vega:OTTHUMG00000149887 +126208 ZNF787 HGNC:HGNC:26998|Ensembl:ENSG00000142409|Vega:OTTHUMG00000181760 +126231 ZNF573 HGNC:HGNC:26420|Ensembl:ENSG00000189144|Vega:OTTHUMG00000048183 +126235 RPS4XP21 HGNC:HGNC:36228 +126242 AKR1B1P7 HGNC:HGNC:33497 +126248 WDR88 HGNC:HGNC:26999|Ensembl:ENSG00000166359|Vega:OTTHUMG00000180342 +126259 TMIGD2 MIM:614715|HGNC:HGNC:28324|Ensembl:ENSG00000167664|Vega:OTTHUMG00000181880 +126272 EID2B HGNC:HGNC:26796|Ensembl:ENSG00000176401|Vega:OTTHUMG00000183068 +126282 TNFAIP8L1 MIM:615869|HGNC:HGNC:28279|Ensembl:ENSG00000185361|Vega:OTTHUMG00000182013 +126295 ZNF57 HGNC:HGNC:13125|Ensembl:ENSG00000171970|Vega:OTTHUMG00000164485 +126298 IRGQ HGNC:HGNC:24868|Ensembl:ENSG00000167378|Vega:OTTHUMG00000182701 +126299 ZNF428 HGNC:HGNC:20804|Ensembl:ENSG00000131116|Vega:OTTHUMG00000182734 +126306 JSRP1 MIM:608743|HGNC:HGNC:24963|Ensembl:ENSG00000167476|Vega:OTTHUMG00000180413 +126308 MOB3A HGNC:HGNC:29802|Ensembl:ENSG00000172081|Vega:OTTHUMG00000180353 +126321 MFSD12 HGNC:HGNC:28299|Ensembl:ENSG00000161091|Vega:OTTHUMG00000180766 +126326 GIPC3 MIM:608792|HGNC:HGNC:18183|Ensembl:ENSG00000179855|Vega:OTTHUMG00000167425 +126328 NDUFA11 MIM:612638|HGNC:HGNC:20371|Ensembl:ENSG00000174886|Vega:OTTHUMG00000180617 +126353 MISP MIM:615289|HGNC:HGNC:27000|Ensembl:ENSG00000099812|Vega:OTTHUMG00000181786 +126364 LRRC25 MIM:607518|HGNC:HGNC:29806|Ensembl:ENSG00000175489|Vega:OTTHUMG00000183361 +126370 OR1I1 HGNC:HGNC:8207|Ensembl:ENSG00000094661|Vega:OTTHUMG00000183206 +126374 WTIP MIM:614790|HGNC:HGNC:20964|Ensembl:ENSG00000142279|Vega:OTTHUMG00000182099 +126375 ZNF792 HGNC:HGNC:24751|Ensembl:ENSG00000180884|Vega:OTTHUMG00000150339 +126382 NR2C2AP MIM:608719|HGNC:HGNC:30763|Ensembl:ENSG00000184162|Vega:OTTHUMG00000169225 +126393 HSPB6 MIM:610695|HGNC:HGNC:26511|Ensembl:ENSG00000004776|Vega:OTTHUMG00000048122 +126402 CCDC105 HGNC:HGNC:26866|Ensembl:ENSG00000160994|Vega:OTTHUMG00000183352 +126410 CYP4F22 MIM:611495|HGNC:HGNC:26820|Ensembl:ENSG00000171954|Vega:OTTHUMG00000182451 +126432 RINL HGNC:HGNC:24795|Ensembl:ENSG00000187994|Vega:OTTHUMG00000182299 +126433 FBXO27 MIM:609099|HGNC:HGNC:18753|Ensembl:ENSG00000161243|Vega:OTTHUMG00000182719 +126506 SNX6P1 HGNC:HGNC:41511 +126520 PLK5 HGNC:HGNC:27001|Ensembl:ENSG00000185988|Vega:OTTHUMG00000180073 +126526 C19orf47 HGNC:HGNC:26723|Ensembl:ENSG00000160392|Vega:OTTHUMG00000179028 +126536 LINC00661 HGNC:HGNC:27002|Ensembl:ENSG00000205396 +126541 OR10H4 HGNC:HGNC:15388|Ensembl:ENSG00000176231|Vega:OTTHUMG00000182268 +126549 ANKLE1 HGNC:HGNC:26812|Ensembl:ENSG00000160117|Vega:OTTHUMG00000150839 +126567 C2CD4C MIM:610336|HGNC:HGNC:29417|Ensembl:ENSG00000183186|Vega:OTTHUMG00000180534 +126581 MRPL57P1 HGNC:HGNC:29686 +126626 GABPB2 HGNC:HGNC:28441|Ensembl:ENSG00000143458|Vega:OTTHUMG00000012193 +126637 TCHHL1 HGNC:HGNC:31796|Ensembl:ENSG00000182898|Vega:OTTHUMG00000013058 +126638 RPTN MIM:613259|HGNC:HGNC:26809|Ensembl:ENSG00000215853|Vega:OTTHUMG00000154095 +126661 CCDC163 HGNC:HGNC:27003|Ensembl:ENSG00000280670|Vega:OTTHUMG00000007741 +126668 TDRD10 HGNC:HGNC:25316|Ensembl:ENSG00000163239|Vega:OTTHUMG00000037264 +126669 SHE MIM:610482|HGNC:HGNC:27004|Ensembl:ENSG00000169291|Vega:OTTHUMG00000036072 +126695 KDF1 MIM:616758|HGNC:HGNC:26624|Ensembl:ENSG00000175707|Vega:OTTHUMG00000004272 +126731 CCSAP MIM:616762|HGNC:HGNC:29578|Ensembl:ENSG00000154429|Vega:OTTHUMG00000037663 +126755 LRRC38 MIM:615212|HGNC:HGNC:27005|Ensembl:ENSG00000162494|Vega:OTTHUMG00000007918 +126767 AADACL3 HGNC:HGNC:32037|Ensembl:ENSG00000188984|Vega:OTTHUMG00000001887 +126789 PUSL1 HGNC:HGNC:26914|Ensembl:ENSG00000169972|Vega:OTTHUMG00000003361 +126792 B3GALT6 MIM:615291|HGNC:HGNC:17978|Ensembl:ENSG00000176022|Vega:OTTHUMG00000001813 +126811 KRT8P21 HGNC:HGNC:33373 +126820 WDR63 HGNC:HGNC:30711|Ensembl:ENSG00000162643|Vega:OTTHUMG00000009953 +126823 KLHDC9 MIM:617375|HGNC:HGNC:28489|Ensembl:ENSG00000162755|Vega:OTTHUMG00000031479 +126826 TGIF2P1 HGNC:HGNC:33317 +126859 AXDND1 HGNC:HGNC:26564|Ensembl:ENSG00000162779|Vega:OTTHUMG00000035266 +126860 LOC126860 - +126868 MAB21L3 HGNC:HGNC:26787|Ensembl:ENSG00000173212|Vega:OTTHUMG00000012110 +126917 IFFO2 HGNC:HGNC:27006|Ensembl:ENSG00000169991|Vega:OTTHUMG00000002499 +126961 HIST2H3C MIM:142780|HGNC:HGNC:20503|Ensembl:ENSG00000203811|Vega:OTTHUMG00000012190 +126969 SLC44A3 HGNC:HGNC:28689|Ensembl:ENSG00000143036|Vega:OTTHUMG00000010700 +126987 LOC126987 - +127002 ATXN7L2 HGNC:HGNC:28713|Ensembl:ENSG00000162650|Vega:OTTHUMG00000011027 +127003 C1orf194 HGNC:HGNC:32331|Ensembl:ENSG00000179902|Vega:OTTHUMG00000011735 +127011 LOC127011 - +127018 LYPLAL1 MIM:616548|HGNC:HGNC:20440|Ensembl:ENSG00000143353|Vega:OTTHUMG00000037141 +127059 OR2M5 HGNC:HGNC:19576|Ensembl:ENSG00000162727|Vega:OTTHUMG00000040447 +127062 OR2M3 HGNC:HGNC:8269|Ensembl:ENSG00000228198|Vega:OTTHUMG00000040459 +127064 OR2T12 HGNC:HGNC:19592|Ensembl:ENSG00000177201|Vega:OTTHUMG00000040457 +127066 OR14C36 HGNC:HGNC:15026|Ensembl:ENSG00000177174|Vega:OTTHUMG00000040463 +127068 OR2T34 HGNC:HGNC:31256|Ensembl:ENSG00000183310|Vega:OTTHUMG00000040387 +127069 OR2T10 HGNC:HGNC:19573|Ensembl:ENSG00000184022|Vega:OTTHUMG00000040388 +127074 OR2T4 HGNC:HGNC:15016|Ensembl:ENSG00000196944|Vega:OTTHUMG00000040453 +127077 OR2T11 HGNC:HGNC:19574|Ensembl:ENSG00000279301|Vega:OTTHUMG00000040384 +127086 XRCC6P3 HGNC:HGNC:45185 +127099 RPLP1P3 HGNC:HGNC:36870 +127124 ATP6V1G3 HGNC:HGNC:18265|Ensembl:ENSG00000151418|Vega:OTTHUMG00000035661 +127247 ASB17 HGNC:HGNC:19769|Ensembl:ENSG00000154007|Vega:OTTHUMG00000009787 +127253 TYW3 MIM:611245|HGNC:HGNC:24757|Ensembl:ENSG00000162623|Vega:OTTHUMG00000009641 +127254 ERICH3 HGNC:HGNC:25346|Ensembl:ENSG00000178965|Vega:OTTHUMG00000009622 +127255 LRRIQ3 HGNC:HGNC:28318|Ensembl:ENSG00000162620|Vega:OTTHUMG00000009508 +127262 TPRG1L MIM:611460|HGNC:HGNC:27007|Ensembl:ENSG00000158109|Vega:OTTHUMG00000000609 +127281 FAM213B HGNC:HGNC:28390|Ensembl:ENSG00000157870|Vega:OTTHUMG00000000847 +127294 MYOM3 MIM:616832|HGNC:HGNC:26679|Ensembl:ENSG00000142661|Vega:OTTHUMG00000002969 +127295 RPL36P5 HGNC:HGNC:35567 +127343 DMBX1 MIM:607410|HGNC:HGNC:19026|Ensembl:ENSG00000197587|Vega:OTTHUMG00000007982 +127385 OR10J5 HGNC:HGNC:14993|Ensembl:ENSG00000184155|Vega:OTTHUMG00000022738 +127391 TMCO2 HGNC:HGNC:23312|Ensembl:ENSG00000188800|Vega:OTTHUMG00000005764 +127396 ZNF684 HGNC:HGNC:28418|Ensembl:ENSG00000117010|Vega:OTTHUMG00000007359 +127406 RPSAP20 HGNC:HGNC:35595 +127428 TCEANC2 HGNC:HGNC:26494|Ensembl:ENSG00000116205|Vega:OTTHUMG00000008434 +127435 PODN MIM:608661|HGNC:HGNC:23174|Ensembl:ENSG00000174348|Vega:OTTHUMG00000008934 +127481 S100A7P1 HGNC:HGNC:21654 +127495 LRRC39 HGNC:HGNC:28228|Ensembl:ENSG00000122477|Vega:OTTHUMG00000010839 +127534 GJB4 MIM:605425|HGNC:HGNC:4286|Ensembl:ENSG00000189433|Vega:OTTHUMG00000004052 +127540 HMGB4 MIM:617285|HGNC:HGNC:24954|Ensembl:ENSG00000176256|Vega:OTTHUMG00000013143 +127544 RNF19B MIM:610872|HGNC:HGNC:26886|Ensembl:ENSG00000116514|Vega:OTTHUMG00000004013 +127545 RPL18AP4 HGNC:HGNC:36556 +127550 A3GALT2 HGNC:HGNC:30005|Ensembl:ENSG00000184389|Vega:OTTHUMG00000004125 +127579 DCST2 HGNC:HGNC:26562|Ensembl:ENSG00000163354|Vega:OTTHUMG00000037371 +127602 DNAH14 MIM:603341|HGNC:HGNC:2945|Ensembl:ENSG00000185842|Vega:OTTHUMG00000037447 +127608 OR2AJ1 HGNC:HGNC:15001 +127617 OR14L1P HGNC:HGNC:15023 +127623 OR2B11 HGNC:HGNC:31249|Ensembl:ENSG00000177535|Vega:OTTHUMG00000040572 +127665 ZNF648 HGNC:HGNC:18190|Ensembl:ENSG00000179930|Vega:OTTHUMG00000037302 +127670 TEDDM1 HGNC:HGNC:30233|Ensembl:ENSG00000203730|Vega:OTTHUMG00000037398 +127671 TEDDM2P HGNC:HGNC:42447 +127687 C1orf122 HGNC:HGNC:24789|Ensembl:ENSG00000197982|Vega:OTTHUMG00000004319 +127700 OSCP1 MIM:608854|HGNC:HGNC:29971|Ensembl:ENSG00000116885|Vega:OTTHUMG00000008139 +127703 C1orf216 HGNC:HGNC:26800|Ensembl:ENSG00000142686|Vega:OTTHUMG00000004167 +127707 KLHDC7A HGNC:HGNC:26791|Ensembl:ENSG00000179023|Vega:OTTHUMG00000002431 +127731 VWA5B1 HGNC:HGNC:26538|Ensembl:ENSG00000158816|Vega:OTTHUMG00000002835 +127733 UBXN10 MIM:616783|HGNC:HGNC:26354|Ensembl:ENSG00000162543|Vega:OTTHUMG00000002708 +127795 C1orf87 HGNC:HGNC:28547|Ensembl:ENSG00000162598|Vega:OTTHUMG00000008992 +127829 ARL8A MIM:616597|HGNC:HGNC:25192|Ensembl:ENSG00000143862|Vega:OTTHUMG00000035923 +127833 SYT2 MIM:600104|HGNC:HGNC:11510|Ensembl:ENSG00000143858|Vega:OTTHUMG00000041388 +127841 LINC00628 HGNC:HGNC:27008|Ensembl:ENSG00000280924 +127845 GOLT1A HGNC:HGNC:24766|Ensembl:ENSG00000174567|Vega:OTTHUMG00000036056 +127933 UHMK1 MIM:608849|HGNC:HGNC:19683|Ensembl:ENSG00000152332|Vega:OTTHUMG00000031373 +127943 FCRLB MIM:609251|HGNC:HGNC:26431|Ensembl:ENSG00000162746|Vega:OTTHUMG00000133629 +128025 WDR64 HGNC:HGNC:26570|Ensembl:ENSG00000162843 +128061 C1orf131 HGNC:HGNC:25332|Ensembl:ENSG00000143633|Vega:OTTHUMG00000038023 +128077 LIX1L HGNC:HGNC:28715|Ensembl:ENSG00000271601|Vega:OTTHUMG00000013741 +128102 HSD3BP4 HGNC:HGNC:5222 +128136 LOC128136 - +128153 SPATA17 MIM:611032|HGNC:HGNC:25184|Ensembl:ENSG00000162814|Vega:OTTHUMG00000037875 +128178 EDARADD MIM:606603|HGNC:HGNC:14341|Ensembl:ENSG00000186197|Vega:OTTHUMG00000039954 +128192 LOC128192 - +128209 KLF17 MIM:609602|HGNC:HGNC:18830|Ensembl:ENSG00000171872|Vega:OTTHUMG00000009664 +128218 TMEM125 HGNC:HGNC:28275|Ensembl:ENSG00000179178|Vega:OTTHUMG00000007288 +128229 TSACC HGNC:HGNC:30636|Ensembl:ENSG00000163467|Vega:OTTHUMG00000024060 +128239 IQGAP3 HGNC:HGNC:20669|Ensembl:ENSG00000183856|Vega:OTTHUMG00000033114 +128240 NAXE MIM:608862|HGNC:HGNC:18453|Ensembl:ENSG00000163382|Vega:OTTHUMG00000033206 +128272 ARHGEF19 MIM:612496|HGNC:HGNC:26604|Ensembl:ENSG00000142632|Vega:OTTHUMG00000002219 +128308 MRPL55 MIM:611859|HGNC:HGNC:16686|Ensembl:ENSG00000162910|Vega:OTTHUMG00000037965 +128312 HIST3H2BB MIM:615046|HGNC:HGNC:20514|Ensembl:ENSG00000196890|Vega:OTTHUMG00000040045 +128322 NUTF2P4 HGNC:HGNC:50453 +128338 DRAM2 MIM:613360|HGNC:HGNC:28769|Ensembl:ENSG00000156171|Vega:OTTHUMG00000011911 +128344 PIFO MIM:614234|HGNC:HGNC:27009|Ensembl:ENSG00000173947|Vega:OTTHUMG00000011168 +128346 C1orf162 HGNC:HGNC:28344|Ensembl:ENSG00000143110|Vega:OTTHUMG00000011750 +128360 OR10T2 HGNC:HGNC:14816|Ensembl:ENSG00000186306|Vega:OTTHUMG00000017521 +128366 OR6P1 HGNC:HGNC:15036|Ensembl:ENSG00000186440|Vega:OTTHUMG00000019633 +128367 OR10X1 HGNC:HGNC:14995|Ensembl:ENSG00000279111|Vega:OTTHUMG00000019635 +128368 OR10Z1 HGNC:HGNC:14996|Ensembl:ENSG00000198967|Vega:OTTHUMG00000019637 +128370 OR6K4P HGNC:HGNC:15031 +128371 OR6K6 HGNC:HGNC:15033|Ensembl:ENSG00000180433|Vega:OTTHUMG00000022772 +128372 OR6N1 HGNC:HGNC:15034|Ensembl:ENSG00000197403|Vega:OTTHUMG00000022774 +128387 TATDN3 HGNC:HGNC:27010|Ensembl:ENSG00000203705|Vega:OTTHUMG00000036805 +128408 BHLHE23 MIM:609331|HGNC:HGNC:16093|Ensembl:ENSG00000125533|Vega:OTTHUMG00000032948 +128414 NKAIN4 MIM:612873|HGNC:HGNC:16191|Ensembl:ENSG00000101198|Vega:OTTHUMG00000032959 +128434 VSTM2L MIM:616537|HGNC:HGNC:16096|Ensembl:ENSG00000132821|Vega:OTTHUMG00000032430 +128439 SNHG11 HGNC:HGNC:25046|Ensembl:ENSG00000174365 +128467 RPL12P11 HGNC:HGNC:15835 +128481 RPL27AP HGNC:HGNC:16250 +128486 FITM2 MIM:612029|HGNC:HGNC:16135|Ensembl:ENSG00000197296|Vega:OTTHUMG00000032522 +128488 WFDC12 MIM:609872|HGNC:HGNC:16115|Ensembl:ENSG00000168703|Vega:OTTHUMG00000046412 +128497 SPATA25 HGNC:HGNC:16158|Ensembl:ENSG00000149634|Vega:OTTHUMG00000032628 +128500 RPL13P2 HGNC:HGNC:16342 +128506 OCSTAMP HGNC:HGNC:16116|Ensembl:ENSG00000149635|Vega:OTTHUMG00000032652 +128553 TSHZ2 MIM:614118|HGNC:HGNC:13010|Ensembl:ENSG00000182463|Vega:OTTHUMG00000033058 +128580 RPS4XP3 HGNC:HGNC:16251 +128602 C20orf85 HGNC:HGNC:16216|Ensembl:ENSG00000124237|Vega:OTTHUMG00000032836 +128609 MRPS16P2 HGNC:HGNC:16541 +128611 ZNF831 HGNC:HGNC:16167|Ensembl:ENSG00000124203|Vega:OTTHUMG00000032864 +128615 PIEZO1P1 HGNC:HGNC:16214 +128637 TBC1D20 MIM:611663|HGNC:HGNC:16133|Ensembl:ENSG00000125875|Vega:OTTHUMG00000031637 +128646 SIRPD HGNC:HGNC:16248|Ensembl:ENSG00000125900|Vega:OTTHUMG00000031674 +128653 C20orf141 HGNC:HGNC:16134|Ensembl:ENSG00000258713|Vega:OTTHUMG00000031707 +128668 RPL7AP12 HGNC:HGNC:16562 +128674 PROKR2 MIM:607123|HGNC:HGNC:15836|Ensembl:ENSG00000101292|Vega:OTTHUMG00000031800 +128676 RPS18P1 HGNC:HGNC:16550 +128709 RPL23AP6 HGNC:HGNC:16555 +128710 SLX4IP MIM:615958|HGNC:HGNC:16225|Ensembl:ENSG00000149346|Vega:OTTHUMG00000031873 +128718 RPS11P1 HGNC:HGNC:16553 +128745 RPLP0P1 HGNC:HGNC:16585 +128748 RPL7AP13 HGNC:HGNC:16565 +128756 RPL15P1 HGNC:HGNC:16583 +128760 RPL21P3 HGNC:HGNC:16533 +128770 EIF4E2P1 HGNC:HGNC:16237 +128774 MRPS11P1 HGNC:HGNC:16584 +128790 SLC25A6P1 HGNC:HGNC:16554 +128817 CSTL1 HGNC:HGNC:15958|Ensembl:ENSG00000125823|Vega:OTTHUMG00000032068 +128820 CST9LP1 HGNC:HGNC:39552 +128821 CST9L MIM:616536|HGNC:HGNC:16233|Ensembl:ENSG00000101435|Vega:OTTHUMG00000032073 +128822 CST9 MIM:616543|HGNC:HGNC:13261|Ensembl:ENSG00000173335|Vega:OTTHUMG00000032076 +128826 MIR1-1HG HGNC:HGNC:16159 +128848 DKKL1P1 HGNC:HGNC:16593 +128853 DUSP15 MIM:616776|HGNC:HGNC:16236|Ensembl:ENSG00000149599|Vega:OTTHUMG00000032182 +128854 TSPY26P HGNC:HGNC:16256|Ensembl:ENSG00000235217 +128859 BPIFB6 MIM:614110|HGNC:HGNC:16504|Ensembl:ENSG00000167104|Vega:OTTHUMG00000032238 +128861 BPIFA3 HGNC:HGNC:16204|Ensembl:ENSG00000131059|Vega:OTTHUMG00000032245 +128862 RPL12P3 HGNC:HGNC:16335 +128864 C20orf144 HGNC:HGNC:16137|Ensembl:ENSG00000149609|Vega:OTTHUMG00000032263 +128866 CHMP4B MIM:610897|HGNC:HGNC:16171|Ensembl:ENSG00000101421|Vega:OTTHUMG00000032272 +128869 PIGU MIM:608528|HGNC:HGNC:15791|Ensembl:ENSG00000101464|Vega:OTTHUMG00000032304 +128872 HMGB3P1 HGNC:HGNC:16240 +128876 FAM83C HGNC:HGNC:16121|Ensembl:ENSG00000125998|Vega:OTTHUMG00000032332 +128879 HMGB3P2 HGNC:HGNC:16574 +128954 GAB4 HGNC:HGNC:18325|Ensembl:ENSG00000215568|Vega:OTTHUMG00000149992 +128977 C22orf39 HGNC:HGNC:27012|Ensembl:ENSG00000242259|Vega:OTTHUMG00000150137 +128989 TANGO2 MIM:616830|HGNC:HGNC:25439|Ensembl:ENSG00000183597|Vega:OTTHUMG00000150510 +128997 SLC9A3P2 HGNC:HGNC:19325 +129025 ZNF280A HGNC:HGNC:18597|Ensembl:ENSG00000169548|Vega:OTTHUMG00000030545 +129026 LOC129026 - +129049 SGSM1 MIM:611417|HGNC:HGNC:29410|Ensembl:ENSG00000167037|Vega:OTTHUMG00000150837 +129080 EMID1 MIM:608926|HGNC:HGNC:18036|Ensembl:ENSG00000186998|Vega:OTTHUMG00000151013 +129099 CPSF1P1 HGNC:HGNC:19251 +129138 ANKRD54 MIM:613383|HGNC:HGNC:25185|Ensembl:ENSG00000100124|Vega:OTTHUMG00000150663 +129285 PPP1R21 HGNC:HGNC:30595|Ensembl:ENSG00000162869|Vega:OTTHUMG00000129167 +129293 TRABD2A MIM:614912|HGNC:HGNC:27013|Ensembl:ENSG00000186854|Vega:OTTHUMG00000152922 +129303 TMEM150A MIM:616757|HGNC:HGNC:24677|Ensembl:ENSG00000168890|Vega:OTTHUMG00000130168 +129401 NUP35 MIM:608140|HGNC:HGNC:29797|Ensembl:ENSG00000163002|Vega:OTTHUMG00000132621 +129402 LIN28AP1 HGNC:HGNC:38055 +129446 XIRP2 MIM:609778|HGNC:HGNC:14303|Ensembl:ENSG00000163092|Vega:OTTHUMG00000154027 +129450 TYW5 HGNC:HGNC:26754|Ensembl:ENSG00000162971|Vega:OTTHUMG00000132770 +129521 NMS HGNC:HGNC:32203|Ensembl:ENSG00000204640|Vega:OTTHUMG00000153142 +129522 LOC129522 - +129530 LYG1 HGNC:HGNC:27014|Ensembl:ENSG00000144214|Vega:OTTHUMG00000130639 +129531 MITD1 HGNC:HGNC:25207|Ensembl:ENSG00000158411|Vega:OTTHUMG00000130638 +129560 AHCYP4 HGNC:HGNC:44996 +129563 DIS3L2 MIM:614184|HGNC:HGNC:28648|Ensembl:ENSG00000144535|Vega:OTTHUMG00000153385 +129607 CMPK2 MIM:611787|HGNC:HGNC:27015|Ensembl:ENSG00000134326|Vega:OTTHUMG00000151629 +129642 MBOAT2 MIM:611949|HGNC:HGNC:25193|Ensembl:ENSG00000143797|Vega:OTTHUMG00000090363 +129656 LOC129656 - +129684 CNTNAP5 MIM:610519|HGNC:HGNC:18748|Ensembl:ENSG00000155052|Vega:OTTHUMG00000153356 +129685 TAF8 MIM:609514|HGNC:HGNC:17300|Ensembl:ENSG00000137413|Vega:OTTHUMG00000014692 +129787 TMEM18 MIM:613220|HGNC:HGNC:25257|Ensembl:ENSG00000151353|Vega:OTTHUMG00000151381 +129790 C7orf13 MIM:610242|HGNC:HGNC:17126|Ensembl:ENSG00000182648 +129804 FBLN7 MIM:611551|HGNC:HGNC:26740|Ensembl:ENSG00000144152|Vega:OTTHUMG00000153267 +129807 NEU4 MIM:608527|HGNC:HGNC:21328|Ensembl:ENSG00000204099|Vega:OTTHUMG00000133412 +129831 RBM45 MIM:608888|HGNC:HGNC:24468|Ensembl:ENSG00000155636|Vega:OTTHUMG00000154202 +129841 RPSAP25 HGNC:HGNC:36405 +129852 C2orf73 HGNC:HGNC:26861|Ensembl:ENSG00000177994|Vega:OTTHUMG00000151826 +129868 TRIM43 HGNC:HGNC:19015|Ensembl:ENSG00000144015|Vega:OTTHUMG00000130401 +129870 UBTFL3 HGNC:HGNC:35402 +129880 BBS5 MIM:603650|HGNC:HGNC:970|Ensembl:ENSG00000163093|Vega:OTTHUMG00000132207 +129881 CCDC173 HGNC:HGNC:25064|Ensembl:ENSG00000154479|Vega:OTTHUMG00000154116 +130013 ACMSD MIM:608889|HGNC:HGNC:19288|Ensembl:ENSG00000153086|Vega:OTTHUMG00000131711 +130026 ICA1L HGNC:HGNC:14442|Ensembl:ENSG00000163596|Vega:OTTHUMG00000132856 +130074 FAM168B HGNC:HGNC:27016|Ensembl:ENSG00000152102|Vega:OTTHUMG00000153473 +130075 OR9A4 HGNC:HGNC:15095|Ensembl:ENSG00000258083|Vega:OTTHUMG00000158370 +130106 CIB4 MIM:610646|HGNC:HGNC:33703|Ensembl:ENSG00000157884|Vega:OTTHUMG00000151993 +130120 REG3G MIM:609933|HGNC:HGNC:29595|Ensembl:ENSG00000143954|Vega:OTTHUMG00000130018 +130132 RFTN2 HGNC:HGNC:26402|Ensembl:ENSG00000162944|Vega:OTTHUMG00000132746 +130162 CLHC1 HGNC:HGNC:26453|Ensembl:ENSG00000162994|Vega:OTTHUMG00000151918 +130195 HSPA8P6 HGNC:HGNC:44921 +130271 PLEKHH2 MIM:612723|HGNC:HGNC:30506|Ensembl:ENSG00000152527|Vega:OTTHUMG00000128657 +130340 AP1S3 MIM:615781|HGNC:HGNC:18971|Ensembl:ENSG00000152056|Vega:OTTHUMG00000133165 +130355 C2orf76 HGNC:HGNC:27017|Ensembl:ENSG00000186132|Vega:OTTHUMG00000153298 +130367 SGPP2 MIM:612827|HGNC:HGNC:19953|Ensembl:ENSG00000163082|Vega:OTTHUMG00000133156 +130399 ACVR1C MIM:608981|HGNC:HGNC:18123|Ensembl:ENSG00000123612|Vega:OTTHUMG00000131964 +130429 RPSAP27 HGNC:HGNC:36650 +130497 OSR1 MIM:608891|HGNC:HGNC:8111|Ensembl:ENSG00000143867|Vega:OTTHUMG00000088793 +130500 CISD1P1 HGNC:HGNC:29611 +130502 TTC32 HGNC:HGNC:32954|Ensembl:ENSG00000183891|Vega:OTTHUMG00000151776 +130507 UBR3 MIM:613831|HGNC:HGNC:30467|Ensembl:ENSG00000144357|Vega:OTTHUMG00000132229 +130535 KCTD18 HGNC:HGNC:26446|Ensembl:ENSG00000155729|Vega:OTTHUMG00000132781 +130540 ALS2CR12 HGNC:HGNC:14439|Ensembl:ENSG00000155749|Vega:OTTHUMG00000132824 +130557 ZNF513 MIM:613598|HGNC:HGNC:26498|Ensembl:ENSG00000163795|Vega:OTTHUMG00000097783 +130560 SPATA3 HGNC:HGNC:17884|Ensembl:ENSG00000173699|Vega:OTTHUMG00000133221 +130574 LYPD6 MIM:613359|HGNC:HGNC:28751|Ensembl:ENSG00000187123|Vega:OTTHUMG00000131852 +130576 LYPD6B HGNC:HGNC:27018|Ensembl:ENSG00000150556|Vega:OTTHUMG00000153743 +130589 GALM MIM:137030|HGNC:HGNC:24063|Ensembl:ENSG00000143891|Vega:OTTHUMG00000102077 +130612 TMEM198 HGNC:HGNC:33704|Ensembl:ENSG00000188760|Vega:OTTHUMG00000059156 +130617 ZFAND2B MIM:613474|HGNC:HGNC:25206|Ensembl:ENSG00000158552|Vega:OTTHUMG00000133135 +130678 RPLP1P5 HGNC:HGNC:35842 +130700 PSMB3P2 HGNC:HGNC:30150 +130728 RPL7P13 HGNC:HGNC:36861 +130733 TMEM178A HGNC:HGNC:28517|Ensembl:ENSG00000152154|Vega:OTTHUMG00000128591 +130749 CPO MIM:609563|HGNC:HGNC:21011|Ensembl:ENSG00000144410|Vega:OTTHUMG00000088987 +130752 MDH1B HGNC:HGNC:17836|Ensembl:ENSG00000138400|Vega:OTTHUMG00000132918 +130773 RPL23AP37 HGNC:HGNC:35664 +130802 DNMT3AP1 HGNC:HGNC:23164 +130813 C2orf50 HGNC:HGNC:26324|Ensembl:ENSG00000150873|Vega:OTTHUMG00000119057 +130814 PQLC3 HGNC:HGNC:28503|Ensembl:ENSG00000162976|Vega:OTTHUMG00000119055 +130827 TMEM182 HGNC:HGNC:26391|Ensembl:ENSG00000170417|Vega:OTTHUMG00000130779 +130865 RPL26P13 HGNC:HGNC:36639 +130872 AHSA2 HGNC:HGNC:20437|Ensembl:ENSG00000173209|Vega:OTTHUMG00000129437 +130888 FBXO36 MIM:609105|HGNC:HGNC:27020|Ensembl:ENSG00000153832|Vega:OTTHUMG00000133206 +130916 MTERF4 MIM:615393|HGNC:HGNC:28785|Ensembl:ENSG00000122085|Vega:OTTHUMG00000133393 +130940 CCDC148 HGNC:HGNC:25191|Ensembl:ENSG00000153237|Vega:OTTHUMG00000153973 +130951 M1AP HGNC:HGNC:25183|Ensembl:ENSG00000159374|Vega:OTTHUMG00000152918 +131034 CPNE4 MIM:604208|HGNC:HGNC:2317|Ensembl:ENSG00000196353|Vega:OTTHUMG00000159631 +131054 LOC131054 - +131055 LOC131055 - +131076 CCDC58 HGNC:HGNC:31136|Ensembl:ENSG00000160124|Vega:OTTHUMG00000159490 +131096 KCNH8 MIM:608260|HGNC:HGNC:18864|Ensembl:ENSG00000183960|Vega:OTTHUMG00000129891 +131118 DNAJC19 MIM:608977|HGNC:HGNC:30528|Ensembl:ENSG00000205981|Vega:OTTHUMG00000158180 +131149 OTOL1 HGNC:HGNC:34071|Ensembl:ENSG00000182447|Vega:OTTHUMG00000159074 +131177 FAM3D MIM:608619|HGNC:HGNC:18665|Ensembl:ENSG00000198643|Vega:OTTHUMG00000159148 +131185 RAD23BP1 HGNC:HGNC:44509 +131368 ZPLD1 MIM:615915|HGNC:HGNC:27022|Ensembl:ENSG00000170044|Vega:OTTHUMG00000159229 +131375 LYZL4 MIM:612750|HGNC:HGNC:28387|Ensembl:ENSG00000157093|Vega:OTTHUMG00000131793 +131377 KLHL40 MIM:615340|HGNC:HGNC:30372|Ensembl:ENSG00000157119|Vega:OTTHUMG00000133045 +131405 TRIM71 HGNC:HGNC:32669|Ensembl:ENSG00000206557|Vega:OTTHUMG00000155778 +131408 FAM131A HGNC:HGNC:28308|Ensembl:ENSG00000175182|Vega:OTTHUMG00000156206 +131450 CD200R1 MIM:607546|HGNC:HGNC:24235|Ensembl:ENSG00000163606|Vega:OTTHUMG00000159298 +131474 CHCHD4 MIM:611077|HGNC:HGNC:26467|Ensembl:ENSG00000163528|Vega:OTTHUMG00000129805 +131540 ZDHHC19 HGNC:HGNC:20713|Ensembl:ENSG00000163958|Vega:OTTHUMG00000133642 +131544 CRYBG3 HGNC:HGNC:34427|Ensembl:ENSG00000080200|Vega:OTTHUMG00000159187 +131566 DCBLD2 MIM:608698|HGNC:HGNC:24627|Ensembl:ENSG00000057019|Vega:OTTHUMG00000151985 +131572 MESTP4 HGNC:HGNC:38554 +131578 LRRC15 HGNC:HGNC:20818|Ensembl:ENSG00000172061|Vega:OTTHUMG00000156048 +131583 FAM43A HGNC:HGNC:26888|Ensembl:ENSG00000185112|Vega:OTTHUMG00000156016 +131601 TPRA1 MIM:608336|HGNC:HGNC:30413|Ensembl:ENSG00000163870|Vega:OTTHUMG00000159639 +131616 TMEM42 HGNC:HGNC:28444|Ensembl:ENSG00000169964|Vega:OTTHUMG00000133092 +131669 UROC1 MIM:613012|HGNC:HGNC:26444|Ensembl:ENSG00000159650|Vega:OTTHUMG00000162753 +131831 ERICH6 HGNC:HGNC:28602|Ensembl:ENSG00000163645|Vega:OTTHUMG00000133569 +131870 NUDT16 MIM:617381|HGNC:HGNC:26442|Ensembl:ENSG00000198585|Vega:OTTHUMG00000159623 +131873 COL6A6 MIM:616613|HGNC:HGNC:27023|Ensembl:ENSG00000206384|Vega:OTTHUMG00000159653 +131890 GRK7 MIM:606987|HGNC:HGNC:17031|Ensembl:ENSG00000114124|Vega:OTTHUMG00000159068 +131909 FAM172BP HGNC:HGNC:34336 +131920 TMEM207 MIM:614786|HGNC:HGNC:33705|Ensembl:ENSG00000198398|Vega:OTTHUMG00000156213 +131961 IMPDH1P8 HGNC:HGNC:33963 +131965 METTL6 HGNC:HGNC:28343|Ensembl:ENSG00000206562|Vega:OTTHUMG00000156431 +131973 RHBDF1P1 HGNC:HGNC:44499 +132001 TAMM41 MIM:614948|HGNC:HGNC:25187|Ensembl:ENSG00000144559|Vega:OTTHUMG00000129741 +132014 IL17RE MIM:614995|HGNC:HGNC:18439|Ensembl:ENSG00000163701|Vega:OTTHUMG00000128649 +132112 RTP1 MIM:609137|HGNC:HGNC:28580|Ensembl:ENSG00000175077|Vega:OTTHUMG00000149886 +132141 IQCF1 HGNC:HGNC:28607|Ensembl:ENSG00000173389|Vega:OTTHUMG00000156908 +132158 GLYCTK MIM:610516|HGNC:HGNC:24247|Ensembl:ENSG00000168237|Vega:OTTHUMG00000158380 +132160 PPM1M MIM:608979|HGNC:HGNC:26506|Ensembl:ENSG00000164088|Vega:OTTHUMG00000153046 +132200 C3orf49 HGNC:HGNC:25190|Ensembl:ENSG00000163632|Vega:OTTHUMG00000158761 +132203 SNTN HGNC:HGNC:33706|Ensembl:ENSG00000188817|Vega:OTTHUMG00000158766 +132204 SYNPR HGNC:HGNC:16507|Ensembl:ENSG00000163630|Vega:OTTHUMG00000158699 +132228 LSMEM2 HGNC:HGNC:26781|Ensembl:ENSG00000179564|Vega:OTTHUMG00000156938 +132241 RPL32P3 HGNC:HGNC:27024|Ensembl:ENSG00000251474 +132243 H1FOO HGNC:HGNC:18463|Ensembl:ENSG00000178804|Vega:OTTHUMG00000159541 +132299 OCIAD2 HGNC:HGNC:28685|Ensembl:ENSG00000145247|Vega:OTTHUMG00000128626 +132320 SCLT1 MIM:611399|HGNC:HGNC:26406|Ensembl:ENSG00000151466|Vega:OTTHUMG00000133346 +132321 C4orf33 HGNC:HGNC:27025|Ensembl:ENSG00000151470|Vega:OTTHUMG00000133347 +132332 TMEM155 HGNC:HGNC:26418|Ensembl:ENSG00000164112|Vega:OTTHUMG00000133035 +132386 LOC132386 - +132391 KRT18P21 HGNC:HGNC:33389 +132430 PABPC4L HGNC:HGNC:31955|Ensembl:ENSG00000254535|Vega:OTTHUMG00000161292 +132556 BTF3P13 MIM:603739|HGNC:HGNC:1128 +132612 ADAD1 MIM:614130|HGNC:HGNC:30713|Ensembl:ENSG00000164113|Vega:OTTHUMG00000150128 +132625 ZFP42 MIM:614572|HGNC:HGNC:30949|Ensembl:ENSG00000179059|Vega:OTTHUMG00000160235 +132660 LIN54 MIM:613367|HGNC:HGNC:25397|Ensembl:ENSG00000189308|Vega:OTTHUMG00000130287 +132671 SPATA18 MIM:612814|HGNC:HGNC:29579|Ensembl:ENSG00000163071|Vega:OTTHUMG00000128698 +132719 TUBB8P3 HGNC:HGNC:42338 +132720 FAM241A HGNC:HGNC:26813|Ensembl:ENSG00000174749|Vega:OTTHUMG00000132851 +132724 TMPRSS11B HGNC:HGNC:25398|Ensembl:ENSG00000185873|Vega:OTTHUMG00000129301 +132789 GNPDA2 MIM:613222|HGNC:HGNC:21526|Ensembl:ENSG00000163281|Vega:OTTHUMG00000099415 +132817 RBM48P1 HGNC:HGNC:44054 +132851 SPATA4 MIM:609879|HGNC:HGNC:17333|Ensembl:ENSG00000150628|Vega:OTTHUMG00000160788 +132864 CPEB2 MIM:610605|HGNC:HGNC:21745|Ensembl:ENSG00000137449 +132884 EVC2 MIM:607261|HGNC:HGNC:19747|Ensembl:ENSG00000173040|Vega:OTTHUMG00000125493 +132946 ARL9 MIM:612405|HGNC:HGNC:23592|Ensembl:ENSG00000196503|Vega:OTTHUMG00000184000 +132949 AASDH MIM:614365|HGNC:HGNC:23993|Ensembl:ENSG00000157426|Vega:OTTHUMG00000128841 +132954 PDCL2 MIM:611676|HGNC:HGNC:29524|Ensembl:ENSG00000163440|Vega:OTTHUMG00000160674 +132989 C4orf36 HGNC:HGNC:28386|Ensembl:ENSG00000163633|Vega:OTTHUMG00000130597 +133015 PACRGL HGNC:HGNC:28442|Ensembl:ENSG00000163138|Vega:OTTHUMG00000128550 +133022 TRAM1L1 MIM:617505|HGNC:HGNC:28371|Ensembl:ENSG00000174599|Vega:OTTHUMG00000132956 +133060 OTOP1 MIM:607806|HGNC:HGNC:19656|Ensembl:ENSG00000163982|Vega:OTTHUMG00000090301 +133083 PMPCAP1 HGNC:HGNC:51348 +133121 ENPP6 MIM:616983|HGNC:HGNC:23409|Ensembl:ENSG00000164303|Vega:OTTHUMG00000160617 +133150 SULT1D1P HGNC:HGNC:30659 +133283 EEF1A1P13 HGNC:HGNC:3196 +133308 SLC9B2 MIM:611789|HGNC:HGNC:25143|Ensembl:ENSG00000164038|Vega:OTTHUMG00000131125 +133332 LOC133332 - +133383 SETD9 HGNC:HGNC:28508|Ensembl:ENSG00000155542|Vega:OTTHUMG00000059485 +133396 IL31RA MIM:609510|HGNC:HGNC:18969|Ensembl:ENSG00000164509|Vega:OTTHUMG00000097045 +133418 EMB MIM:615669|HGNC:HGNC:30465|Ensembl:ENSG00000170571|Vega:OTTHUMG00000131161 +133482 SLCO6A1 MIM:613365|HGNC:HGNC:23613|Ensembl:ENSG00000205359|Vega:OTTHUMG00000162759 +133491 C5orf47 HGNC:HGNC:27026|Ensembl:ENSG00000185056|Vega:OTTHUMG00000163349 +133522 PPARGC1B MIM:608886|HGNC:HGNC:30022|Ensembl:ENSG00000155846|Vega:OTTHUMG00000130055 +133558 MROH2B HGNC:HGNC:26857|Ensembl:ENSG00000171495|Vega:OTTHUMG00000162151 +133569 RPS10P12 HGNC:HGNC:36662 +133584 EGFLAM HGNC:HGNC:26810|Ensembl:ENSG00000164318|Vega:OTTHUMG00000131139 +133609 RPLP1P7 HGNC:HGNC:36156 +133615 MRPS5P3 HGNC:HGNC:29778 +133619 PRRC1 HGNC:HGNC:28164|Ensembl:ENSG00000164244|Vega:OTTHUMG00000128982 +133629 RPL11P2 HGNC:HGNC:36983 +133686 NADK2 MIM:615787|HGNC:HGNC:26404|Ensembl:ENSG00000152620|Vega:OTTHUMG00000131105 +133688 UGT3A1 MIM:616383|HGNC:HGNC:26625|Ensembl:ENSG00000145626|Vega:OTTHUMG00000131107 +133690 CAPSL HGNC:HGNC:28375|Ensembl:ENSG00000152611|Vega:OTTHUMG00000131109 +133746 JMY MIM:604279|HGNC:HGNC:28916|Ensembl:ENSG00000152409|Vega:OTTHUMG00000131301 +133748 RPL7AP32 HGNC:HGNC:36415 +133789 RAB5CP2 HGNC:HGNC:45106 +133790 RPS18P7 HGNC:HGNC:35874 +133874 C5orf58 HGNC:HGNC:37272|Ensembl:ENSG00000234511|Vega:OTTHUMG00000163122 +133923 ZNF474 HGNC:HGNC:23245|Ensembl:ENSG00000164185|Vega:OTTHUMG00000128911 +133957 CCDC127 HGNC:HGNC:30520|Ensembl:ENSG00000164366|Vega:OTTHUMG00000161586 +134008 MRPL11P2 HGNC:HGNC:29694 +134082 OR2AI1P HGNC:HGNC:15063 +134083 OR2Y1 HGNC:HGNC:14837|Ensembl:ENSG00000174339|Vega:OTTHUMG00000162237 +134111 UBE2QL1 MIM:615832|HGNC:HGNC:37269|Ensembl:ENSG00000215218|Vega:OTTHUMG00000161683 +134121 C5orf49 HGNC:HGNC:27028|Ensembl:ENSG00000215217|Vega:OTTHUMG00000161897 +134145 FAM173B HGNC:HGNC:27029|Ensembl:ENSG00000150756|Vega:OTTHUMG00000161771 +134147 CMBL MIM:613379|HGNC:HGNC:25090|Ensembl:ENSG00000164237|Vega:OTTHUMG00000131043 +134187 POU5F2 HGNC:HGNC:26367|Ensembl:ENSG00000248483|Vega:OTTHUMG00000162644 +134218 DNAJC21 MIM:617048|HGNC:HGNC:27030|Ensembl:ENSG00000168724|Vega:OTTHUMG00000074103 +134265 AFAP1L1 MIM:614410|HGNC:HGNC:26714|Ensembl:ENSG00000157510|Vega:OTTHUMG00000163441 +134266 GRPEL2 HGNC:HGNC:21060|Ensembl:ENSG00000164284|Vega:OTTHUMG00000130048 +134285 TMEM171 HGNC:HGNC:27031|Ensembl:ENSG00000157111|Vega:OTTHUMG00000131269 +134288 TMEM174 MIM:614909|HGNC:HGNC:28187|Ensembl:ENSG00000164325|Vega:OTTHUMG00000131268 +134353 LSM11 HGNC:HGNC:30860|Ensembl:ENSG00000155858|Vega:OTTHUMG00000130255 +134359 POC5 HGNC:HGNC:26658|Ensembl:ENSG00000152359|Vega:OTTHUMG00000162487 +134391 GPR151 HGNC:HGNC:23624|Ensembl:ENSG00000173250|Vega:OTTHUMG00000163444 +134429 STARD4 MIM:607049|HGNC:HGNC:18058|Ensembl:ENSG00000164211|Vega:OTTHUMG00000128793 +134430 WDR36 MIM:609669|HGNC:HGNC:30696|Ensembl:ENSG00000134987|Vega:OTTHUMG00000128790 +134466 ZNF300P1 HGNC:HGNC:27032 +134490 MRPL57P6 HGNC:HGNC:29689 +134492 NUDCD2 HGNC:HGNC:30535|Ensembl:ENSG00000170584|Vega:OTTHUMG00000130378 +134505 EIF3KP1 HGNC:HGNC:44016 +134510 UBLCP1 MIM:609867|HGNC:HGNC:28110|Ensembl:ENSG00000164332|Vega:OTTHUMG00000130305 +134526 ACOT12 MIM:614315|HGNC:HGNC:24436|Ensembl:ENSG00000172497|Vega:OTTHUMG00000131305 +134548 SOWAHA HGNC:HGNC:27033|Ensembl:ENSG00000198944|Vega:OTTHUMG00000059844 +134549 SHROOM1 MIM:611179|HGNC:HGNC:24084|Ensembl:ENSG00000164403|Vega:OTTHUMG00000059835 +134553 C5orf24 HGNC:HGNC:26746|Ensembl:ENSG00000181904|Vega:OTTHUMG00000129121 +134637 ADAT2 MIM:615388|HGNC:HGNC:21172|Ensembl:ENSG00000189007|Vega:OTTHUMG00000015725 +134701 RIPPLY2 MIM:609891|HGNC:HGNC:21390|Ensembl:ENSG00000203877|Vega:OTTHUMG00000015117 +134728 IRAK1BP1 MIM:615375|HGNC:HGNC:17368|Ensembl:ENSG00000146243|Vega:OTTHUMG00000015070 +134756 RPL29P1 HGNC:HGNC:21593 +134829 CLVS2 MIM:616945|HGNC:HGNC:23046|Ensembl:ENSG00000146352|Vega:OTTHUMG00000015495 +134860 TAAR9 MIM:608282|HGNC:HGNC:20977|Ensembl:ENSG00000237110|Vega:OTTHUMG00000015578 +134864 TAAR1 MIM:609333|HGNC:HGNC:17734|Ensembl:ENSG00000146399|Vega:OTTHUMG00000015583 +134957 STXBP5 MIM:604586|HGNC:HGNC:19665|Ensembl:ENSG00000164506|Vega:OTTHUMG00000015766 +134997 PPIAP29 HGNC:HGNC:43021 +135112 NCOA7 MIM:609752|HGNC:HGNC:21081|Ensembl:ENSG00000111912|Vega:OTTHUMG00000015513 +135114 HINT3 MIM:609998|HGNC:HGNC:18468|Ensembl:ENSG00000111911|Vega:OTTHUMG00000015514 +135138 PACRG MIM:608427|HGNC:HGNC:19152|Ensembl:ENSG00000112530|Vega:OTTHUMG00000016116 +135152 B3GAT2 MIM:607497|HGNC:HGNC:922|Ensembl:ENSG00000112309|Vega:OTTHUMG00000014997 +135154 SDHAF4 HGNC:HGNC:20957|Ensembl:ENSG00000154079|Vega:OTTHUMG00000014992 +135228 CD109 MIM:608859|HGNC:HGNC:21685|Ensembl:ENSG00000156535|Vega:OTTHUMG00000015040 +135250 RAET1E MIM:609243|HGNC:HGNC:16793|Ensembl:ENSG00000164520|Vega:OTTHUMG00000015796 +135270 COPS5P1 HGNC:HGNC:24332 +135293 PM20D2 MIM:615913|HGNC:HGNC:21408|Ensembl:ENSG00000146281|Vega:OTTHUMG00000015193 +135295 SRSF12 HGNC:HGNC:21220|Ensembl:ENSG00000154548|Vega:OTTHUMG00000015192 +135398 C6orf141 HGNC:HGNC:21351|Ensembl:ENSG00000197261|Vega:OTTHUMG00000014820 +135458 HUS1B MIM:609713|HGNC:HGNC:16485|Ensembl:ENSG00000188996|Vega:OTTHUMG00000090059 +135644 TRIM40 MIM:616976|HGNC:HGNC:18736|Ensembl:ENSG00000204614|Vega:OTTHUMG00000031083 +135656 DPCR1 MIM:613928|HGNC:HGNC:21666|Ensembl:ENSG00000168631|Vega:OTTHUMG00000031104 +135886 TMEM270 MIM:612547|HGNC:HGNC:23018|Ensembl:ENSG00000175877|Vega:OTTHUMG00000157243 +135892 TRIM50 MIM:612548|HGNC:HGNC:19017|Ensembl:ENSG00000146755|Vega:OTTHUMG00000156805 +135924 OR9A2 HGNC:HGNC:15093|Ensembl:ENSG00000179468|Vega:OTTHUMG00000158386 +135927 C7orf34 HGNC:HGNC:21750|Ensembl:ENSG00000165131|Vega:OTTHUMG00000152664 +135932 TMEM139 MIM:616524|HGNC:HGNC:22058|Ensembl:ENSG00000178826|Vega:OTTHUMG00000152652 +135935 NOBOX MIM:610934|HGNC:HGNC:22448|Ensembl:ENSG00000106410|Vega:OTTHUMG00000158051 +135941 OR2A14 HGNC:HGNC:15084|Ensembl:ENSG00000221938|Vega:OTTHUMG00000158003 +135942 OR2A15P HGNC:HGNC:15085 +135946 OR6B1 HGNC:HGNC:8354|Ensembl:ENSG00000221813|Vega:OTTHUMG00000157765 +135948 OR2F2 HGNC:HGNC:8247|Ensembl:ENSG00000221910|Vega:OTTHUMG00000157768 +136051 ZNF786 HGNC:HGNC:21806|Ensembl:ENSG00000197362|Vega:OTTHUMG00000158975 +136157 SSU72P8 HGNC:HGNC:43627 +136227 COL26A1 MIM:608927|HGNC:HGNC:18038|Ensembl:ENSG00000160963|Vega:OTTHUMG00000150033 +136242 PRSS37 HGNC:HGNC:29211|Ensembl:ENSG00000165076|Vega:OTTHUMG00000157174 +136259 KLF14 MIM:609393|HGNC:HGNC:23025|Ensembl:ENSG00000266265|Vega:OTTHUMG00000188298 +136263 SSMEM1 HGNC:HGNC:29580|Ensembl:ENSG00000165120|Vega:OTTHUMG00000157844 +136288 C7orf57 HGNC:HGNC:22247|Ensembl:ENSG00000164746|Vega:OTTHUMG00000155808 +136306 SVOPL MIM:611700|HGNC:HGNC:27034|Ensembl:ENSG00000157703|Vega:OTTHUMG00000155870 +136307 IMPDH1P3 HGNC:HGNC:33958 +136319 MTPN MIM:606484|HGNC:HGNC:15667|Ensembl:ENSG00000105887|Vega:OTTHUMG00000155627 +136332 LRGUK MIM:616478|HGNC:HGNC:21964|Ensembl:ENSG00000155530|Vega:OTTHUMG00000155320 +136371 ASB10 MIM:615054|HGNC:HGNC:17185|Ensembl:ENSG00000146926|Vega:OTTHUMG00000157013 +136540 PRSS3P3 HGNC:HGNC:43790 +136541 PRSS58 HGNC:HGNC:39125|Ensembl:ENSG00000258223|Vega:OTTHUMG00000158565 +136647 MPLKIP MIM:609188|HGNC:HGNC:16002|Ensembl:ENSG00000168303|Vega:OTTHUMG00000128797 +136853 SSC4D MIM:607639|HGNC:HGNC:14461|Ensembl:ENSG00000146700|Vega:OTTHUMG00000022864 +136895 C7orf31 MIM:616071|HGNC:HGNC:21722|Ensembl:ENSG00000153790|Vega:OTTHUMG00000128497 +136991 ASZ1 MIM:605797|HGNC:HGNC:1350|Ensembl:ENSG00000154438|Vega:OTTHUMG00000064565 +137012 PPM1AP1 HGNC:HGNC:30175 +137075 CLDN23 MIM:609203|HGNC:HGNC:17591|Ensembl:ENSG00000253958|Vega:OTTHUMG00000163674 +137107 RPL10AP3 HGNC:HGNC:29803 +137133 PSAT1P1 HGNC:HGNC:15785 +137196 CCDC26 MIM:613040|HGNC:HGNC:28416|Ensembl:ENSG00000229140 +137209 ZNF572 HGNC:HGNC:26758|Ensembl:ENSG00000180938|Vega:OTTHUMG00000164988 +137290 MRPL9P1 HGNC:HGNC:29726 +137362 GOT1L1 HGNC:HGNC:28487|Ensembl:ENSG00000169154|Vega:OTTHUMG00000164027 +137392 FAM92A MIM:617273|HGNC:HGNC:30452|Ensembl:ENSG00000188343|Vega:OTTHUMG00000164238 +137406 MRPS16P1 HGNC:HGNC:29732 +137492 VPS37A MIM:609927|HGNC:HGNC:24928|Ensembl:ENSG00000155975|Vega:OTTHUMG00000130785 +137529 CKS1BP7 HGNC:HGNC:1999 +137682 NDUFAF6 MIM:612392|HGNC:HGNC:28625|Ensembl:ENSG00000156170|Vega:OTTHUMG00000150173 +137695 TMEM68 HGNC:HGNC:26510|Ensembl:ENSG00000167904|Vega:OTTHUMG00000164293 +137735 ABRA MIM:609747|HGNC:HGNC:30655|Ensembl:ENSG00000174429|Vega:OTTHUMG00000164809 +137797 LYPD2 HGNC:HGNC:25215|Ensembl:ENSG00000197353|Vega:OTTHUMG00000164686 +137814 NKX2-6 MIM:611770|HGNC:HGNC:32940|Ensembl:ENSG00000180053|Vega:OTTHUMG00000163867 +137835 TMEM71 HGNC:HGNC:26572|Ensembl:ENSG00000165071|Vega:OTTHUMG00000164647 +137868 SGCZ MIM:608113|HGNC:HGNC:14075|Ensembl:ENSG00000185053|Vega:OTTHUMG00000090827 +137872 ADHFE1 MIM:611083|HGNC:HGNC:16354|Ensembl:ENSG00000147576|Vega:OTTHUMG00000150215 +137886 UBXN2B MIM:610686|HGNC:HGNC:27035|Ensembl:ENSG00000215114|Vega:OTTHUMG00000164300 +137902 PXDNL MIM:615904|HGNC:HGNC:26359|Ensembl:ENSG00000147485|Vega:OTTHUMG00000164244 +137964 GPAT4 MIM:608143|HGNC:HGNC:20880|Ensembl:ENSG00000158669|Vega:OTTHUMG00000164082 +137970 UNC5D MIM:616466|HGNC:HGNC:18634|Ensembl:ENSG00000156687|Vega:OTTHUMG00000157145 +137994 LETM2 HGNC:HGNC:14648|Ensembl:ENSG00000165046|Vega:OTTHUMG00000165059 +138009 DCAF4L2 HGNC:HGNC:26657|Ensembl:ENSG00000176566|Vega:OTTHUMG00000163767 +138046 RALYL MIM:614648|HGNC:HGNC:27036|Ensembl:ENSG00000184672|Vega:OTTHUMG00000164628 +138050 HGSNAT MIM:610453|HGNC:HGNC:26527|Ensembl:ENSG00000165102|Vega:OTTHUMG00000164102 +138065 RNF183 HGNC:HGNC:28721|Ensembl:ENSG00000165188|Vega:OTTHUMG00000020520 +138151 NACC2 MIM:615786|HGNC:HGNC:23846|Ensembl:ENSG00000148411|Vega:OTTHUMG00000020921 +138159 LOC138159 - +138162 C9orf116 MIM:614502|HGNC:HGNC:28435|Ensembl:ENSG00000160345|Vega:OTTHUMG00000020902 +138199 CARNMT1 MIM:616552|HGNC:HGNC:23435|Ensembl:ENSG00000156017|Vega:OTTHUMG00000020032 +138234 ATP5HP2 HGNC:HGNC:49624 +138240 C9orf57 HGNC:HGNC:27037|Ensembl:ENSG00000204669|Vega:OTTHUMG00000020003 +138241 C9orf85 HGNC:HGNC:28784|Ensembl:ENSG00000155621|Vega:OTTHUMG00000020002 +138255 C9orf135 HGNC:HGNC:31422|Ensembl:ENSG00000204711|Vega:OTTHUMG00000019985 +138307 LCN8 MIM:612902|HGNC:HGNC:27038|Ensembl:ENSG00000204001|Vega:OTTHUMG00000020942 +138311 FAM69B MIM:614543|HGNC:HGNC:28290|Ensembl:ENSG00000165716|Vega:OTTHUMG00000020940 +138412 SLC25A6P2 HGNC:HGNC:43850 +138428 PTRH1 HGNC:HGNC:27039|Ensembl:ENSG00000187024|Vega:OTTHUMG00000020710 +138429 PIP5KL1 MIM:612865|HGNC:HGNC:28711|Ensembl:ENSG00000167103|Vega:OTTHUMG00000020719 +138474 TAF1L MIM:607798|HGNC:HGNC:18056|Ensembl:ENSG00000122728|Vega:OTTHUMG00000019747 +138639 PTPDC1 HGNC:HGNC:30184|Ensembl:ENSG00000158079|Vega:OTTHUMG00000020258 +138649 ANKRD19P HGNC:HGNC:22567|Ensembl:ENSG00000187984 +138652 PRSS47 HGNC:HGNC:37326 +138715 ARID3C HGNC:HGNC:21209|Ensembl:ENSG00000205143|Vega:OTTHUMG00000000445 +138716 RPP25L HGNC:HGNC:19909|Ensembl:ENSG00000164967|Vega:OTTHUMG00000000443 +138724 C9orf131 HGNC:HGNC:31418|Ensembl:ENSG00000174038|Vega:OTTHUMG00000019853 +138799 OR13C5 HGNC:HGNC:15100|Ensembl:ENSG00000277556|Vega:OTTHUMG00000020408 +138802 OR13C8 HGNC:HGNC:15103|Ensembl:ENSG00000186943|Vega:OTTHUMG00000020409 +138803 OR13C3 HGNC:HGNC:14704|Ensembl:ENSG00000204246|Vega:OTTHUMG00000020406 +138804 OR13C4 HGNC:HGNC:14722|Ensembl:ENSG00000148136|Vega:OTTHUMG00000020407 +138805 OR13F1 HGNC:HGNC:14723|Ensembl:ENSG00000186881|Vega:OTTHUMG00000020404 +138864 ATP5HP3 HGNC:HGNC:49625 +138881 OR1L8 HGNC:HGNC:15110|Ensembl:ENSG00000171496|Vega:OTTHUMG00000020609 +138882 OR1N2 HGNC:HGNC:15111|Ensembl:ENSG00000171501|Vega:OTTHUMG00000020607 +138883 OR1N1 HGNC:HGNC:8221|Ensembl:ENSG00000171505|Vega:OTTHUMG00000020608 +138916 SYNGR2P2 HGNC:HGNC:33947 +138948 DBH-AS1 HGNC:HGNC:24155|Ensembl:ENSG00000225756 +138971 DPP3P2 HGNC:HGNC:51350 +139041 PSMAGEA - +139060 KRT18P68 HGNC:HGNC:48895 +139061 LOC139061 - +139065 SLITRK4 MIM:300562|HGNC:HGNC:23502|Ensembl:ENSG00000179542|Vega:OTTHUMG00000022580 +139067 SPANXN3 MIM:300666|HGNC:HGNC:33176|Ensembl:ENSG00000189252|Vega:OTTHUMG00000022582 +139081 MAGEC3 MIM:300469|HGNC:HGNC:23798|Ensembl:ENSG00000165509|Vega:OTTHUMG00000022570 +139105 BEND2 HGNC:HGNC:28509|Ensembl:ENSG00000177324|Vega:OTTHUMG00000021211 +139135 PASD1 MIM:300993|HGNC:HGNC:20686|Ensembl:ENSG00000166049|Vega:OTTHUMG00000024169 +139163 SALL1P1 HGNC:HGNC:10525 +139170 DCAF12L1 HGNC:HGNC:29395|Ensembl:ENSG00000198889|Vega:OTTHUMG00000022353 +139189 DGKK MIM:300837|HGNC:HGNC:32395|Ensembl:ENSG00000274588|Vega:OTTHUMG00000021520 +139201 MAP2K4P1 HGNC:HGNC:43837|Ensembl:ENSG00000269904 +139212 PIH1D3 MIM:300933|HGNC:HGNC:28570|Ensembl:ENSG00000080572|Vega:OTTHUMG00000022160 +139221 MUM1L1 HGNC:HGNC:26583|Ensembl:ENSG00000157502|Vega:OTTHUMG00000022146 +139231 FAM199X HGNC:HGNC:25195|Ensembl:ENSG00000123575|Vega:OTTHUMG00000022126 +139249 FAM47DP HGNC:HGNC:34342 +139285 AMER1 MIM:300647|HGNC:HGNC:26837|Ensembl:ENSG00000184675|Vega:OTTHUMG00000021703 +139322 APOOL MIM:300955|HGNC:HGNC:24009|Ensembl:ENSG00000155008|Vega:OTTHUMG00000021930 +139324 HDX MIM:300994|HGNC:HGNC:26411|Ensembl:ENSG00000165259|Vega:OTTHUMG00000021926 +139334 IMPDH1P4 HGNC:HGNC:33959 +139341 FUNDC1 MIM:300871|HGNC:HGNC:28746|Ensembl:ENSG00000069509|Vega:OTTHUMG00000021399 +139363 MAGEA13P HGNC:HGNC:35154 +139378 ADGRG4 HGNC:HGNC:18992|Ensembl:ENSG00000156920|Vega:OTTHUMG00000022508 +139411 PTCHD1 MIM:300828|HGNC:HGNC:26392|Ensembl:ENSG00000165186|Vega:OTTHUMG00000021251 +139420 PPP4R3CP HGNC:HGNC:33146|Ensembl:ENSG00000224960|Vega:OTTHUMG00000021300 +139422 MAGEB10 MIM:300761|HGNC:HGNC:25377|Ensembl:ENSG00000177689|Vega:OTTHUMG00000046084 +139425 DCAF8L1 HGNC:HGNC:31810|Ensembl:ENSG00000226372|Vega:OTTHUMG00000021312 +139431 FTH1P14 HGNC:HGNC:39090 +139452 RPL6P30 HGNC:HGNC:36171 +139516 AKAP17BP HGNC:HGNC:38514 +139538 VENTXP1 HGNC:HGNC:30900|Ensembl:ENSG00000259849 +139542 E2F6P4 HGNC:HGNC:51452 +139562 OTUD6A MIM:300714|HGNC:HGNC:32312|Ensembl:ENSG00000189401|Vega:OTTHUMG00000159996 +139596 UPRT MIM:300656|HGNC:HGNC:28334|Ensembl:ENSG00000094841|Vega:OTTHUMG00000021864 +139599 MAGEE2 MIM:300760|HGNC:HGNC:24935|Ensembl:ENSG00000186675|Vega:OTTHUMG00000021870 +139604 MAGEB16 MIM:300762|HGNC:HGNC:21188|Ensembl:ENSG00000189023|Vega:OTTHUMG00000021348 +139628 FOXR2 MIM:300949|HGNC:HGNC:30469|Ensembl:ENSG00000189299|Vega:OTTHUMG00000021661 +139629 XAGE-4 Ensembl:ENSG00000169164 +139716 GAB3 MIM:300482|HGNC:HGNC:17515|Ensembl:ENSG00000160219|Vega:OTTHUMG00000024245 +139728 PNCK MIM:300680|HGNC:HGNC:13415|Ensembl:ENSG00000130822|Vega:OTTHUMG00000024216 +139735 ZFP92 HGNC:HGNC:12865|Ensembl:ENSG00000189420|Vega:OTTHUMG00000024198 +139741 ACTRT1 MIM:300487|HGNC:HGNC:24027|Ensembl:ENSG00000123165|Vega:OTTHUMG00000022359 +139748 KRT18P44 HGNC:HGNC:33414 +139760 GPR119 MIM:300513|HGNC:HGNC:19060|Ensembl:ENSG00000147262|Vega:OTTHUMG00000022397 +139793 PAGE3 MIM:300739|HGNC:HGNC:4110|Ensembl:ENSG00000204279|Vega:OTTHUMG00000021654 +139804 RBMXL3 HGNC:HGNC:26859|Ensembl:ENSG00000175718|Vega:OTTHUMG00000022230 +139818 DOCK11 MIM:300681|HGNC:HGNC:23483|Ensembl:ENSG00000147251|Vega:OTTHUMG00000022256 +139886 SPIN4 HGNC:HGNC:27040|Ensembl:ENSG00000186767|Vega:OTTHUMG00000021696 +139952 LOC139952 - +139957 LOC139957 - +140004 TUBB1P2 HGNC:HGNC:23981 +140028 GAPDHP19 HGNC:HGNC:23947 +140032 RPS4Y2 MIM:400030|HGNC:HGNC:18501|Ensembl:ENSG00000280969|Vega:OTTHUMG00000036540 +140043 CDY10P HGNC:HGNC:23848 +140100 RBMY2KP HGNC:HGNC:23888 +140101 RBMY2MP HGNC:HGNC:23889 +140123 RBMY2CP HGNC:HGNC:23260 +140258 KRTAP13-1 MIM:608718|HGNC:HGNC:18924|Ensembl:ENSG00000198390|Vega:OTTHUMG00000057800 +140290 TCP10L MIM:608365|HGNC:HGNC:11657|Ensembl:ENSG00000242220|Vega:OTTHUMG00000064901 +140432 RNF113B HGNC:HGNC:17267|Ensembl:ENSG00000139797|Vega:OTTHUMG00000017245 +140451 SCA9 MIM:612876|HGNC:HGNC:13440 +140453 MUC17 MIM:608424|HGNC:HGNC:16800|Ensembl:ENSG00000169876|Vega:OTTHUMG00000157030 +140454 PSORS8 MIM:610707|HGNC:HGNC:17322 +140456 ASB11 MIM:300626|HGNC:HGNC:17186|Ensembl:ENSG00000165192|Vega:OTTHUMG00000021173 +140458 ASB5 MIM:615050|HGNC:HGNC:17180|Ensembl:ENSG00000164122|Vega:OTTHUMG00000160793 +140459 ASB6 MIM:615051|HGNC:HGNC:17181|Ensembl:ENSG00000148331|Vega:OTTHUMG00000020787 +140460 ASB7 MIM:615052|HGNC:HGNC:17182|Ensembl:ENSG00000183475|Vega:OTTHUMG00000149868 +140461 ASB8 MIM:615053|HGNC:HGNC:17183|Ensembl:ENSG00000177981|Vega:OTTHUMG00000167834 +140462 ASB9 MIM:300890|HGNC:HGNC:17184|Ensembl:ENSG00000102048|Vega:OTTHUMG00000021172 +140464 PISRT1 HGNC:HGNC:16671 +140465 MYL6B MIM:609930|HGNC:HGNC:29823|Ensembl:ENSG00000196465|Vega:OTTHUMG00000170199 +140467 ZNF358 HGNC:HGNC:16838|Ensembl:ENSG00000198816|Vega:OTTHUMG00000182582 +140468 COX11P1 HGNC:HGNC:2262 +140469 MYO3B MIM:610040|HGNC:HGNC:15576|Ensembl:ENSG00000071909|Vega:OTTHUMG00000154002 +140545 RNF32 MIM:610241|HGNC:HGNC:17118|Ensembl:ENSG00000105982|Vega:OTTHUMG00000151440 +140560 LI5 MIM:606545 +140564 APOBEC3D MIM:609900|HGNC:HGNC:17354|Ensembl:ENSG00000243811|Ensembl:ENSG00000284554|Vega:OTTHUMG00000151084 +140576 S100A16 MIM:617437|HGNC:HGNC:20441|Ensembl:ENSG00000188643|Vega:OTTHUMG00000013545 +140578 CHODL MIM:607247|HGNC:HGNC:17807|Ensembl:ENSG00000154645|Vega:OTTHUMG00000074519 +140596 DEFB104A HGNC:HGNC:18115|Ensembl:ENSG00000176782|Vega:OTTHUMG00000150014 +140597 TCEAL2 HGNC:HGNC:29818|Ensembl:ENSG00000184905|Vega:OTTHUMG00000022048 +140603 COX6B1P1 HGNC:HGNC:2281 +140606 SELENOM MIM:610918|HGNC:HGNC:30397|Ensembl:ENSG00000198832|Vega:OTTHUMG00000151207 +140609 NEK7 MIM:606848|HGNC:HGNC:13386|Ensembl:ENSG00000151414|Vega:OTTHUMG00000035658 +140612 ZFP28 MIM:616798|HGNC:HGNC:17801|Ensembl:ENSG00000196867|Vega:OTTHUMG00000181944 +140623 FAUP1 HGNC:HGNC:17984 +140625 ACTRT2 MIM:608535|HGNC:HGNC:24026|Ensembl:ENSG00000169717|Vega:OTTHUMG00000000562 +140628 GATA5 MIM:611496|HGNC:HGNC:15802|Ensembl:ENSG00000130700|Vega:OTTHUMG00000032919 +140660 RPL21P4 HGNC:HGNC:17959 +140678 MLLT10P1 HGNC:HGNC:15794 +140679 SLC32A1 MIM:616440|HGNC:HGNC:11018|Ensembl:ENSG00000101438|Vega:OTTHUMG00000032457 +140680 C20orf96 HGNC:HGNC:16227|Ensembl:ENSG00000196476|Vega:OTTHUMG00000031626 +140683 BPIFA2 HGNC:HGNC:16203|Ensembl:ENSG00000131050|Vega:OTTHUMG00000032244 +140685 ZBTB46 MIM:614639|HGNC:HGNC:16094|Ensembl:ENSG00000130584|Vega:OTTHUMG00000033001 +140686 WFDC3 HGNC:HGNC:15957|Ensembl:ENSG00000124116|Vega:OTTHUMG00000032614 +140687 GCNT7 HGNC:HGNC:16099|Ensembl:ENSG00000124091 +140688 NOL4L HGNC:HGNC:16106|Ensembl:ENSG00000197183|Vega:OTTHUMG00000032219 +140689 CBLN4 MIM:615029|HGNC:HGNC:16231|Ensembl:ENSG00000054803|Vega:OTTHUMG00000032782 +140690 CTCFL MIM:607022|HGNC:HGNC:16234|Ensembl:ENSG00000124092|Vega:OTTHUMG00000032829 +140691 TRIM69 MIM:616017|HGNC:HGNC:17857|Ensembl:ENSG00000185880|Vega:OTTHUMG00000131246 +140692 COX7BP2 HGNC:HGNC:16601 +140695 RPL7P2 HGNC:HGNC:16336 +140696 RPL37P1 HGNC:HGNC:16337 +140697 RPL36P1 HGNC:HGNC:16338 +140699 MROH8 HGNC:HGNC:16125|Ensembl:ENSG00000101353|Vega:OTTHUMG00000032407 +140700 SAMD10 HGNC:HGNC:16129|Ensembl:ENSG00000130590|Vega:OTTHUMG00000033011 +140701 ABHD16B HGNC:HGNC:16128|Ensembl:ENSG00000183260|Vega:OTTHUMG00000033010 +140706 CCM2L HGNC:HGNC:16153|Ensembl:ENSG00000101331|Vega:OTTHUMG00000032197 +140707 BRI3BP MIM:615627|HGNC:HGNC:14251|Ensembl:ENSG00000184992|Vega:OTTHUMG00000168548 +140710 SOGA1 HGNC:HGNC:16111|Ensembl:ENSG00000149639|Vega:OTTHUMG00000032395 +140711 TLDC2 HGNC:HGNC:16112|Ensembl:ENSG00000101342|Vega:OTTHUMG00000032400 +140713 RPS3AP3 HGNC:HGNC:16537 +140714 RPS27AP3 HGNC:HGNC:16538 +140715 RPL21P2 HGNC:HGNC:16539 +140716 RPL35AP HGNC:HGNC:16546 +140717 RPL37AP1 HGNC:HGNC:16548 +140718 RPL31P3 HGNC:HGNC:16549 +140719 RPL39P HGNC:HGNC:16558 +140730 RIMS4 MIM:611601|HGNC:HGNC:16183|Ensembl:ENSG00000101098|Vega:OTTHUMG00000032546 +140731 ANKRD60 HGNC:HGNC:16217|Ensembl:ENSG00000124227|Vega:OTTHUMG00000032837 +140732 SUN5 MIM:613942|HGNC:HGNC:16252|Ensembl:ENSG00000167098|Vega:OTTHUMG00000032239 +140733 MACROD2 MIM:611567|HGNC:HGNC:16126|Ensembl:ENSG00000172264|Vega:OTTHUMG00000031919 +140735 DYNLL2 MIM:608942|HGNC:HGNC:24596|Ensembl:ENSG00000264364|Vega:OTTHUMG00000178783 +140738 TMEM37 HGNC:HGNC:18216|Ensembl:ENSG00000171227|Vega:OTTHUMG00000153304 +140739 UBE2F HGNC:HGNC:12480|Ensembl:ENSG00000184182|Vega:OTTHUMG00000133341 +140748 RPL17P1 HGNC:HGNC:16559 +140749 RPL5P2 HGNC:HGNC:16568 +140750 RPL36P4 HGNC:HGNC:16569 +140751 RPL36P2 HGNC:HGNC:16570 +140752 RPS27AP2 HGNC:HGNC:16572 +140753 RPL31P2 HGNC:HGNC:16575 +140754 RPS3P1 HGNC:HGNC:16579 +140755 RPS2P1 HGNC:HGNC:16580 +140756 RPL7AP14 HGNC:HGNC:16590 +140757 RSL24D1P6 HGNC:HGNC:37876 +140758 RPS10P2 HGNC:HGNC:16594 +140759 RPL19P1 HGNC:HGNC:16595 +140760 RPL24P2 HGNC:HGNC:16597 +140761 RPS3P2 HGNC:HGNC:16603 +140766 ADAMTS14 MIM:607506|HGNC:HGNC:14899|Ensembl:ENSG00000138316|Vega:OTTHUMG00000018414 +140767 NRSN1 MIM:616630|HGNC:HGNC:17881|Ensembl:ENSG00000152954|Vega:OTTHUMG00000016406 +140771 SMCR5 HGNC:HGNC:17918|Ensembl:ENSG00000226746 +140772 SMCR6 HGNC:HGNC:17919 +140775 SMCR8 MIM:617074|HGNC:HGNC:17921|Ensembl:ENSG00000176994|Vega:OTTHUMG00000059394 +140777 PDB5 HGNC:HGNC:17951 +140778 PDB6 HGNC:HGNC:17952 +140801 RPL10L HGNC:HGNC:17976|Ensembl:ENSG00000165496|Vega:OTTHUMG00000157869 +140802 LGV1 MIM:152430 +140803 TRPM6 MIM:607009|HGNC:HGNC:17995|Ensembl:ENSG00000119121|Vega:OTTHUMG00000020027 +140805 HT MIM:140300 +140807 KRT72 MIM:608246|HGNC:HGNC:28932|Ensembl:ENSG00000170486|Vega:OTTHUMG00000169744 +140809 SRXN1 HGNC:HGNC:16132|Ensembl:ENSG00000271303|Vega:OTTHUMG00000031644 +140821 RSS MIM:180860|HGNC:HGNC:10462 +140823 ROMO1 HGNC:HGNC:16185|Ensembl:ENSG00000125995|Vega:OTTHUMG00000032360 +140825 NEURL2 MIM:608597|HGNC:HGNC:16156|Ensembl:ENSG00000124257|Vega:OTTHUMG00000032626 +140828 LINC00261 HGNC:HGNC:16189|Ensembl:ENSG00000259974|Ensembl:ENSG00000283932 +140831 ZSWIM3 HGNC:HGNC:16157|Ensembl:ENSG00000132801|Vega:OTTHUMG00000032627 +140832 WFDC10A HGNC:HGNC:16139|Ensembl:ENSG00000180305|Vega:OTTHUMG00000046331 +140834 LINC01620 HGNC:HGNC:16195|Ensembl:ENSG00000168746 +140836 BANF2 HGNC:HGNC:16172|Ensembl:ENSG00000125888|Vega:OTTHUMG00000031949 +140838 NANP MIM:610763|HGNC:HGNC:16140|Ensembl:ENSG00000170191|Vega:OTTHUMG00000032132 +140846 FAM83C-AS1 HGNC:HGNC:16113|Ensembl:ENSG00000235214 +140848 MACROD2-IT1 HGNC:HGNC:16201|Ensembl:ENSG00000227927 +140849 LINC00266-1 HGNC:HGNC:16202 +140850 DEFB127 HGNC:HGNC:16206|Ensembl:ENSG00000088782|Vega:OTTHUMG00000031617 +140851 MT1P3 HGNC:HGNC:16120 +140856 SCP2D1 HGNC:HGNC:16211|Ensembl:ENSG00000132631|Vega:OTTHUMG00000031983 +140857 RPL7P3 HGNC:HGNC:16566 +140862 ISM1 MIM:615793|HGNC:HGNC:16213|Ensembl:ENSG00000101230|Vega:OTTHUMG00000031902 +140863 SPINT5P HGNC:HGNC:16161 +140865 LINC00686 HGNC:HGNC:16221 +140870 WFDC6 HGNC:HGNC:16164|Ensembl:ENSG00000243543|Vega:OTTHUMG00000046354 +140871 CFTRP1 HGNC:HGNC:16182 +140873 C20orf173 HGNC:HGNC:16166|Ensembl:ENSG00000125975|Vega:OTTHUMG00000032340 +140875 LINC00028 HGNC:HGNC:16224|Ensembl:ENSG00000233354 +140876 RIPOR3 HGNC:HGNC:16168|Ensembl:ENSG00000042062|Vega:OTTHUMG00000032724 +140880 CST11 MIM:609731|HGNC:HGNC:15959|Ensembl:ENSG00000125831|Vega:OTTHUMG00000032060 +140881 DEFB129 HGNC:HGNC:16218|Ensembl:ENSG00000125903|Vega:OTTHUMG00000031618 +140883 ZNF280B HGNC:HGNC:23022|Ensembl:ENSG00000275004|Vega:OTTHUMG00000151066 +140885 SIRPA MIM:602461|HGNC:HGNC:9662|Ensembl:ENSG00000198053|Vega:OTTHUMG00000031682 +140886 PABPC5 MIM:300407|HGNC:HGNC:13629|Ensembl:ENSG00000174740|Vega:OTTHUMG00000021959 +140890 SREK1 MIM:609268|HGNC:HGNC:17882|Ensembl:ENSG00000153914|Vega:OTTHUMG00000097809 +140892 TCPT MIM:188025 +140893 RBBP8NL HGNC:HGNC:16144|Ensembl:ENSG00000130701|Vega:OTTHUMG00000032913 +140894 CNBD2 HGNC:HGNC:16145|Ensembl:ENSG00000149646|Vega:OTTHUMG00000032371 +140895 HSPE1P1 HGNC:HGNC:16530 +140901 STK35 MIM:609370|HGNC:HGNC:16254|Ensembl:ENSG00000125834|Vega:OTTHUMG00000031688 +140902 R3HDML HGNC:HGNC:16249|Ensembl:ENSG00000101074|Vega:OTTHUMG00000032524 +140907 SPG19 MIM:607152|HGNC:HGNC:16706 +140909 MTCO2P1 HGNC:HGNC:16564 +140913 PPIAP10 HGNC:HGNC:9264 +140921 PPP2R5CP HGNC:HGNC:17835 +140947 DCANP1 MIM:609710|HGNC:HGNC:24459|Ensembl:ENSG00000251380|Vega:OTTHUMG00000163308 +142678 MIB2 MIM:611141|HGNC:HGNC:30577|Ensembl:ENSG00000197530|Vega:OTTHUMG00000074647 +142679 DUSP19 MIM:611437|HGNC:HGNC:18894|Ensembl:ENSG00000162999|Vega:OTTHUMG00000132622 +142680 SLC34A3 MIM:609826|HGNC:HGNC:20305|Ensembl:ENSG00000198569|Vega:OTTHUMG00000131780 +142683 ITLN2 MIM:609874|HGNC:HGNC:20599|Ensembl:ENSG00000158764|Vega:OTTHUMG00000028605 +142684 RAB40A HGNC:HGNC:18283|Ensembl:ENSG00000172476|Vega:OTTHUMG00000022100 +142685 ASB15 HGNC:HGNC:19767|Ensembl:ENSG00000146809|Vega:OTTHUMG00000157114 +142686 ASB14 HGNC:HGNC:19766|Ensembl:ENSG00000239388|Vega:OTTHUMG00000158602 +142689 ASB12 MIM:300891|HGNC:HGNC:19763|Ensembl:ENSG00000198881|Vega:OTTHUMG00000021705 +142827 ACSM6 HGNC:HGNC:31665|Ensembl:ENSG00000173124|Vega:OTTHUMG00000018808 +142891 SAMD8 MIM:611575|HGNC:HGNC:26320|Ensembl:ENSG00000156671|Vega:OTTHUMG00000018515 +142910 LIPJ MIM:613921|HGNC:HGNC:21773|Ensembl:ENSG00000204022|Vega:OTTHUMG00000018691 +142913 CFL1P1 HGNC:HGNC:28560|Ensembl:ENSG00000223820 +142940 TRUB1 MIM:610726|HGNC:HGNC:16060|Ensembl:ENSG00000165832|Vega:OTTHUMG00000019094 +143098 MPP7 MIM:610973|HGNC:HGNC:26542|Ensembl:ENSG00000150054|Vega:OTTHUMG00000017868 +143162 FRMPD2 MIM:613323|HGNC:HGNC:28572|Ensembl:ENSG00000170324|Vega:OTTHUMG00000018171 +143187 VTI1A MIM:614316|HGNC:HGNC:17792|Ensembl:ENSG00000151532|Vega:OTTHUMG00000019063 +143241 DYDC1 MIM:615154|HGNC:HGNC:23460|Ensembl:ENSG00000170788|Vega:OTTHUMG00000018609 +143244 EIF5AL1 HGNC:HGNC:17419|Ensembl:ENSG00000253626|Vega:OTTHUMG00000018563 +143279 HECTD2 HGNC:HGNC:26736|Ensembl:ENSG00000165338|Vega:OTTHUMG00000018742 +143282 FGFBP3 HGNC:HGNC:23428|Ensembl:ENSG00000174721|Vega:OTTHUMG00000018751 +143341 EIF3LP2 HGNC:HGNC:24657 +143371 YWHAZP3 HGNC:HGNC:31101 +143379 C10orf82 HGNC:HGNC:28500|Ensembl:ENSG00000165863|Vega:OTTHUMG00000019105 +143384 CACUL1 HGNC:HGNC:23727|Ensembl:ENSG00000151893|Vega:OTTHUMG00000019138 +143425 SYT9 MIM:613528|HGNC:HGNC:19265|Ensembl:ENSG00000170743|Vega:OTTHUMG00000165499 +143458 LDLRAD3 HGNC:HGNC:27046|Ensembl:ENSG00000179241|Vega:OTTHUMG00000166313 +143471 PSMA8 HGNC:HGNC:22985|Ensembl:ENSG00000154611|Vega:OTTHUMG00000179426 +143496 OR52B4 HGNC:HGNC:15209|Ensembl:ENSG00000221996|Vega:OTTHUMG00000154222 +143501 C11orf40 HGNC:HGNC:23986|Ensembl:ENSG00000171987|Vega:OTTHUMG00000165345 +143502 OR52I2 HGNC:HGNC:15221|Ensembl:ENSG00000226288|Vega:OTTHUMG00000165721 +143503 OR51E1 MIM:611267|HGNC:HGNC:15194|Ensembl:ENSG00000180785|Vega:OTTHUMG00000157024 +143506 SSU72P3 HGNC:HGNC:43622 +143543 RBMXP3 HGNC:HGNC:33949 +143570 XRRA1 MIM:609788|HGNC:HGNC:18868|Ensembl:ENSG00000166435|Vega:OTTHUMG00000165515 +143630 UBQLNL HGNC:HGNC:28294|Ensembl:ENSG00000175518|Vega:OTTHUMG00000066903 +143662 MUC15 MIM:608566|HGNC:HGNC:14956|Ensembl:ENSG00000169550|Vega:OTTHUMG00000166112 +143666 LOC143666 - +143678 C11orf94 HGNC:HGNC:37213|Ensembl:ENSG00000234776|Vega:OTTHUMG00000167004 +143684 FAM76B HGNC:HGNC:28492|Ensembl:ENSG00000077458|Vega:OTTHUMG00000167739 +143686 SESN3 MIM:607768|HGNC:HGNC:23060|Ensembl:ENSG00000149212|Vega:OTTHUMG00000167829 +143689 PIWIL4 MIM:610315|HGNC:HGNC:18444|Ensembl:ENSG00000134627|Vega:OTTHUMG00000167811 +143872 ARHGAP42 MIM:615936|HGNC:HGNC:26545|Ensembl:ENSG00000165895|Vega:OTTHUMG00000167530 +143879 KBTBD3 HGNC:HGNC:22934|Ensembl:ENSG00000182359|Vega:OTTHUMG00000166251 +143884 CWF19L2 HGNC:HGNC:26508|Ensembl:ENSG00000152404|Vega:OTTHUMG00000152975 +143888 KDELC2 HGNC:HGNC:28496|Ensembl:ENSG00000178202|Vega:OTTHUMG00000166535 +143903 LAYN HGNC:HGNC:29471|Ensembl:ENSG00000204381|Vega:OTTHUMG00000166721 +143941 TTC36 HGNC:HGNC:33708|Ensembl:ENSG00000172425|Vega:OTTHUMG00000166338 +144097 C11orf84 HGNC:HGNC:25115|Ensembl:ENSG00000168005|Vega:OTTHUMG00000167746 +144100 PLEKHA7 MIM:612686|HGNC:HGNC:27049|Ensembl:ENSG00000166689|Vega:OTTHUMG00000165954 +144106 ST13P5 HGNC:HGNC:18556 +144108 SPTY2D1 HGNC:HGNC:26818|Ensembl:ENSG00000179119|Vega:OTTHUMG00000167733 +144110 TMEM86A HGNC:HGNC:26890|Ensembl:ENSG00000151117|Vega:OTTHUMG00000167680 +144124 OR10A5 MIM:608493|HGNC:HGNC:15131|Ensembl:ENSG00000166363|Vega:OTTHUMG00000165738 +144125 OR2AG1 HGNC:HGNC:15142|Ensembl:ENSG00000279486|Vega:OTTHUMG00000165735 +144132 DNHD1 MIM:617277|HGNC:HGNC:26532|Ensembl:ENSG00000179532|Vega:OTTHUMG00000133403 +144165 PRICKLE1 MIM:608500|HGNC:HGNC:17019|Ensembl:ENSG00000139174|Vega:OTTHUMG00000169443 +144193 AMDHD1 HGNC:HGNC:28577|Ensembl:ENSG00000139344|Vega:OTTHUMG00000170353 +144195 SLC2A14 MIM:611039|HGNC:HGNC:18301|Ensembl:ENSG00000173262|Vega:OTTHUMG00000168463 +144203 OVOS2 Ensembl:ENSG00000177359|Vega:OTTHUMG00000165051 +144233 BCDIN3D HGNC:HGNC:27050|Ensembl:ENSG00000186666|Vega:OTTHUMG00000169807 +144245 ALG10B HGNC:HGNC:31088|Ensembl:ENSG00000175548|Vega:OTTHUMG00000169298 +144321 GLIPR1L2 MIM:610394|HGNC:HGNC:28592|Ensembl:ENSG00000180481|Vega:OTTHUMG00000169756 +144347 RFLNA MIM:615927|HGNC:HGNC:27051|Ensembl:ENSG00000178882|Vega:OTTHUMG00000168609 +144348 ZNF664 HGNC:HGNC:25406|Ensembl:ENSG00000179195|Vega:OTTHUMG00000168596 +144360 LINC00477 HGNC:HGNC:26557|Ensembl:ENSG00000197503 +144363 ETFRF1 HGNC:HGNC:27052|Ensembl:ENSG00000205707|Vega:OTTHUMG00000171190 +144383 DSPA2D - +144402 CPNE8 HGNC:HGNC:23498|Ensembl:ENSG00000139117|Vega:OTTHUMG00000169396 +144404 TMEM120B MIM:616551|HGNC:HGNC:32008|Ensembl:ENSG00000188735|Vega:OTTHUMG00000169076 +144406 WDR66 HGNC:HGNC:28506|Ensembl:ENSG00000158023|Vega:OTTHUMG00000168948 +144423 GLT1D1 HGNC:HGNC:26483|Ensembl:ENSG00000151948|Vega:OTTHUMG00000168437 +144448 TSPAN19 HGNC:HGNC:31886|Ensembl:ENSG00000231738|Vega:OTTHUMG00000166181 +144453 BEST3 MIM:607337|HGNC:HGNC:17105|Ensembl:ENSG00000127325|Vega:OTTHUMG00000149919 +144455 E2F7 MIM:612046|HGNC:HGNC:23820|Ensembl:ENSG00000165891|Vega:OTTHUMG00000169969 +144481 SOCS2-AS1 MIM:617269|HGNC:HGNC:27054|Ensembl:ENSG00000246985 +144486 CEP83-AS1 HGNC:HGNC:27055|Ensembl:ENSG00000278916 +144501 KRT80 MIM:611161|HGNC:HGNC:27056|Ensembl:ENSG00000167767|Vega:OTTHUMG00000150193 +144535 CFAP54 HGNC:HGNC:26456|Ensembl:ENSG00000188596|Vega:OTTHUMG00000167566 +144568 A2ML1 MIM:610627|HGNC:HGNC:23336|Ensembl:ENSG00000166535|Vega:OTTHUMG00000128499 +144571 A2M-AS1 HGNC:HGNC:27057|Ensembl:ENSG00000245105 +144577 C12orf66 MIM:617420|HGNC:HGNC:26517|Ensembl:ENSG00000174206|Vega:OTTHUMG00000168763 +144581 RPL14P1 HGNC:HGNC:31384 +144608 C12orf60 HGNC:HGNC:28726|Ensembl:ENSG00000182993|Vega:OTTHUMG00000167473 +144638 ST13P3 HGNC:HGNC:18552 +144699 FBXL14 MIM:609081|HGNC:HGNC:28624|Ensembl:ENSG00000171823|Vega:OTTHUMG00000090369 +144712 HMGA1P3 HGNC:HGNC:13323 +144715 RAD9B MIM:608368|HGNC:HGNC:21700|Ensembl:ENSG00000151164|Vega:OTTHUMG00000152952 +144717 FAM109A MIM:614239|HGNC:HGNC:26509|Ensembl:ENSG00000198324|Vega:OTTHUMG00000169547 +144742 LINC00934 HGNC:HGNC:27059|Ensembl:ENSG00000281196 +144766 LINC00355 HGNC:HGNC:27061 +144776 LINC00410 HGNC:HGNC:42742|Ensembl:ENSG00000231674 +144809 FAM216B HGNC:HGNC:26883|Ensembl:ENSG00000179813|Vega:OTTHUMG00000016809 +144811 LACC1 MIM:613409|HGNC:HGNC:26789|Ensembl:ENSG00000179630|Vega:OTTHUMG00000016826 +144817 LINC00330 HGNC:HGNC:42047|Ensembl:ENSG00000235097 +144832 ESRRAP2 HGNC:HGNC:24647 +144847 ESRRAP1 HGNC:HGNC:3472 +144920 LINC00343 HGNC:HGNC:42500 +144983 HNRNPA1L2 HGNC:HGNC:27067|Ensembl:ENSG00000139675|Vega:OTTHUMG00000016972 +145165 ST13P4 HGNC:HGNC:18487 +145173 B3GLCT MIM:610308|HGNC:HGNC:20207|Ensembl:ENSG00000187676|Vega:OTTHUMG00000016688 +145195 C14orf144 HGNC:HGNC:20358 +145200 LINC00239 HGNC:HGNC:20119|Ensembl:ENSG00000258512 +145216 LINC00637 HGNC:HGNC:27069|Ensembl:ENSG00000258735 +145226 RDH12 MIM:608830|HGNC:HGNC:19977|Ensembl:ENSG00000139988|Vega:OTTHUMG00000170032 +145235 RPL24P3 HGNC:HGNC:19784 +145241 ADAM21P1 HGNC:HGNC:19822|Ensembl:ENSG00000235812 +145249 LINC00618 HGNC:HGNC:20110|Ensembl:ENSG00000225163 +145258 GSC MIM:138890|HGNC:HGNC:4612|Ensembl:ENSG00000133937|Vega:OTTHUMG00000170864 +145259 RPSAP4 HGNC:HGNC:20018 +145264 SERPINA12 MIM:617471|HGNC:HGNC:18359|Ensembl:ENSG00000165953|Vega:OTTHUMG00000171349 +145270 PRIMA1 MIM:613851|HGNC:HGNC:18319|Ensembl:ENSG00000175785|Vega:OTTHUMG00000141313 +145282 MIPOL1 MIM:606850|HGNC:HGNC:21460|Ensembl:ENSG00000151338|Vega:OTTHUMG00000140252 +145370 RPL21P7 HGNC:HGNC:19772 +145375 NUP50P1 HGNC:HGNC:20025 +145376 PPP1R36 HGNC:HGNC:20097|Ensembl:ENSG00000165807|Vega:OTTHUMG00000141316 +145389 SLC38A6 MIM:616518|HGNC:HGNC:19863|Ensembl:ENSG00000139974|Vega:OTTHUMG00000140335 +145407 C14orf37 HGNC:HGNC:19846|Ensembl:ENSG00000139971|Vega:OTTHUMG00000171173 +145438 FRMD6-AS1 HGNC:HGNC:20129|Ensembl:ENSG00000273888 +145447 ABHD12B HGNC:HGNC:19837|Ensembl:ENSG00000131969|Vega:OTTHUMG00000140286 +145474 LOC145474 - +145482 PTGR2 MIM:608642|HGNC:HGNC:20149|Ensembl:ENSG00000140043|Vega:OTTHUMG00000171255 +145483 FAM161B HGNC:HGNC:19854|Ensembl:ENSG00000156050|Vega:OTTHUMG00000171259 +145497 LRRC74A HGNC:HGNC:23346|Ensembl:ENSG00000100565|Vega:OTTHUMG00000150153 +145499 RPLP1P1 HGNC:HGNC:19793 +145501 ISM2 MIM:612684|HGNC:HGNC:23176|Ensembl:ENSG00000100593|Vega:OTTHUMG00000158563 +145508 CEP128 HGNC:HGNC:20359|Ensembl:ENSG00000100629|Vega:OTTHUMG00000171442 +145553 MDP1 HGNC:HGNC:28781|Ensembl:ENSG00000213920|Vega:OTTHUMG00000133477 +145567 TTC7B HGNC:HGNC:19858|Ensembl:ENSG00000165914|Vega:OTTHUMG00000171047 +145581 LRFN5 MIM:612811|HGNC:HGNC:20360|Ensembl:ENSG00000165379|Vega:OTTHUMG00000140261 +145624 PWAR1 MIM:600161|HGNC:HGNC:30089|Ensembl:ENSG00000279050 +145645 TERB2 MIM:617131|HGNC:HGNC:28520|Ensembl:ENSG00000167014|Vega:OTTHUMG00000131264 +145694 LOC145694 Ensembl:ENSG00000259426 +145741 C2CD4A MIM:610343|HGNC:HGNC:33627|Ensembl:ENSG00000198535|Vega:OTTHUMG00000171942 +145748 LYSMD4 HGNC:HGNC:26571|Ensembl:ENSG00000183060|Vega:OTTHUMG00000149853 +145767 RPS3AP6 HGNC:HGNC:18630 +145773 FAM81A HGNC:HGNC:28379|Ensembl:ENSG00000157470|Vega:OTTHUMG00000171915 +145781 GCOM1 HGNC:HGNC:26424|Ensembl:ENSG00000137878|Vega:OTTHUMG00000176411 +145783 LOC145783 Ensembl:ENSG00000137871 +145788 C15orf65 HGNC:HGNC:44654|Ensembl:ENSG00000261652|Vega:OTTHUMG00000172679 +145814 PGPEP1L HGNC:HGNC:27080|Ensembl:ENSG00000183571|Vega:OTTHUMG00000171896 +145820 LINC00924 HGNC:HGNC:27081|Ensembl:ENSG00000259134 +145837 DRAIC MIM:616387|HGNC:HGNC:27082 +145845 LOC145845 - +145853 C15orf61 HGNC:HGNC:34453|Ensembl:ENSG00000189227|Vega:OTTHUMG00000172248 +145858 C15orf32 HGNC:HGNC:26549 +145864 HAPLN3 HGNC:HGNC:21446|Ensembl:ENSG00000140511|Vega:OTTHUMG00000148680 +145873 MESP2 MIM:605195|HGNC:HGNC:29659|Ensembl:ENSG00000188095|Vega:OTTHUMG00000172016 +145942 TMCO5A HGNC:HGNC:28558|Ensembl:ENSG00000166069|Vega:OTTHUMG00000129787 +145946 SPATA8 MIM:613948|HGNC:HGNC:28676|Ensembl:ENSG00000185594|Vega:OTTHUMG00000149847 +145957 NRG4 MIM:610894|HGNC:HGNC:29862|Ensembl:ENSG00000169752|Vega:OTTHUMG00000142917 +145978 LINC00052 HGNC:HGNC:26455|Ensembl:ENSG00000259527 +145989 FSCN1P1 HGNC:HGNC:49669 +146050 ZSCAN29 HGNC:HGNC:26673|Ensembl:ENSG00000140265|Vega:OTTHUMG00000130767 +146053 RPS3AP47 HGNC:HGNC:36744 +146057 TTBK2 MIM:611695|HGNC:HGNC:19141|Ensembl:ENSG00000128881|Vega:OTTHUMG00000175802 +146059 CDAN1 MIM:607465|HGNC:HGNC:1713|Ensembl:ENSG00000140326|Vega:OTTHUMG00000175801 +146110 RPL7P47 HGNC:HGNC:35913 +146167 SLC38A8 MIM:615585|HGNC:HGNC:32434|Ensembl:ENSG00000166558|Vega:OTTHUMG00000176588 +146177 VWA3A HGNC:HGNC:27088|Ensembl:ENSG00000175267|Vega:OTTHUMG00000175461 +146183 OTOA MIM:607038|HGNC:HGNC:16378|Ensembl:ENSG00000155719|Vega:OTTHUMG00000090721 +146198 ZFP90 MIM:609451|HGNC:HGNC:23329|Ensembl:ENSG00000184939|Vega:OTTHUMG00000177312 +146206 CARMIL2 MIM:610859|HGNC:HGNC:27089|Ensembl:ENSG00000159753|Vega:OTTHUMG00000184043 +146212 KCTD19 HGNC:HGNC:24753|Ensembl:ENSG00000168676|Vega:OTTHUMG00000173075 +146223 CMTM4 MIM:607887|HGNC:HGNC:19175|Ensembl:ENSG00000183723|Vega:OTTHUMG00000137500 +146225 CMTM2 MIM:607885|HGNC:HGNC:19173|Ensembl:ENSG00000140932|Vega:OTTHUMG00000137501 +146227 BEAN1 MIM:612051|HGNC:HGNC:24160|Ensembl:ENSG00000166546|Vega:OTTHUMG00000173370 +146253 LOC146253 - +146279 TEKT5 HGNC:HGNC:26554|Ensembl:ENSG00000153060|Vega:OTTHUMG00000129750 +146310 RNF151 HGNC:HGNC:23235|Ensembl:ENSG00000179580|Vega:OTTHUMG00000176852 +146325 PRR35 HGNC:HGNC:14139|Ensembl:ENSG00000161992|Vega:OTTHUMG00000154104 +146330 FBXL16 MIM:609082|HGNC:HGNC:14150|Ensembl:ENSG00000127585|Vega:OTTHUMG00000090420 +146336 SSTR5-AS1 HGNC:HGNC:26502|Ensembl:ENSG00000261713 +146378 C16orf92 HGNC:HGNC:26346|Ensembl:ENSG00000167194|Vega:OTTHUMG00000177107 +146395 GSG1L MIM:617161|HGNC:HGNC:28283|Ensembl:ENSG00000169181|Vega:OTTHUMG00000131676 +146429 SLC22A31 HGNC:HGNC:27091|Ensembl:ENSG00000259803 +146433 IL34 MIM:612081|HGNC:HGNC:28529|Ensembl:ENSG00000157368|Vega:OTTHUMG00000137581 +146434 ZNF597 MIM:614685|HGNC:HGNC:26573|Ensembl:ENSG00000167981|Vega:OTTHUMG00000129359 +146439 BICDL2 MIM:617003|HGNC:HGNC:33584|Ensembl:ENSG00000162069|Vega:OTTHUMG00000177452 +146456 TMED6 HGNC:HGNC:28331|Ensembl:ENSG00000157315|Vega:OTTHUMG00000137571 +146481 FRG2DP HGNC:HGNC:27093 +146512 FLJ30679 Ensembl:ENSG00000280278 +146513 LINC02135 HGNC:HGNC:27094|Ensembl:ENSG00000268532 +146540 ZNF785 HGNC:HGNC:26496|Ensembl:ENSG00000197162|Vega:OTTHUMG00000176950 +146542 ZNF688 HGNC:HGNC:30489|Ensembl:ENSG00000229809|Vega:OTTHUMG00000132408 +146547 PRSS36 MIM:610560|HGNC:HGNC:26906|Ensembl:ENSG00000178226|Vega:OTTHUMG00000176751 +146556 C16orf89 HGNC:HGNC:28687|Ensembl:ENSG00000153446|Vega:OTTHUMG00000159314 +146562 C16orf71 HGNC:HGNC:25081|Ensembl:ENSG00000166246|Vega:OTTHUMG00000129480 +146664 MGAT5B MIM:612441|HGNC:HGNC:24140|Ensembl:ENSG00000167889|Vega:OTTHUMG00000177278 +146691 TOM1L2 MIM:615519|HGNC:HGNC:11984|Ensembl:ENSG00000175662|Vega:OTTHUMG00000059353 +146705 TEPSIN HGNC:HGNC:26458|Ensembl:ENSG00000167302|Vega:OTTHUMG00000177866 +146712 B3GNTL1 MIM:615337|HGNC:HGNC:21727|Ensembl:ENSG00000175711|Vega:OTTHUMG00000177788 +146713 RBFOX3 MIM:616999|HGNC:HGNC:27097|Ensembl:ENSG00000167281|Vega:OTTHUMG00000150183 +146722 CD300LF MIM:609807|HGNC:HGNC:29883|Ensembl:ENSG00000186074|Vega:OTTHUMG00000067609 +146723 C17orf77 HGNC:HGNC:26480 +146754 DNAH2 MIM:603333|HGNC:HGNC:2948|Ensembl:ENSG00000183914|Vega:OTTHUMG00000178020 +146760 RTN4RL1 MIM:610461|HGNC:HGNC:21329|Ensembl:ENSG00000185924|Vega:OTTHUMG00000180184 +146771 TCAM1P MIM:612756|HGNC:HGNC:30707|Ensembl:ENSG00000240280 +146779 EFCAB3 HGNC:HGNC:26379|Ensembl:ENSG00000172421|Vega:OTTHUMG00000179175 +146795 LINC02003 HGNC:HGNC:27099|Ensembl:ENSG00000264026 +146802 SLC47A2 MIM:609833|HGNC:HGNC:26439|Ensembl:ENSG00000180638|Vega:OTTHUMG00000059464 +146822 CDRT15 HGNC:HGNC:14395|Ensembl:ENSG00000223510|Vega:OTTHUMG00000179686 +146845 CFAP52 MIM:609804|HGNC:HGNC:16053|Ensembl:ENSG00000166596|Vega:OTTHUMG00000150149 +146849 CCDC42 HGNC:HGNC:26528|Ensembl:ENSG00000161973|Vega:OTTHUMG00000178565 +146850 PIK3R6 MIM:611462|HGNC:HGNC:27101|Ensembl:ENSG00000276231|Vega:OTTHUMG00000132861 +146852 ODF4 MIM:610097|HGNC:HGNC:19056|Ensembl:ENSG00000184650|Vega:OTTHUMG00000108190 +146853 C17orf50 HGNC:HGNC:29581|Ensembl:ENSG00000270806|Vega:OTTHUMG00000188389 +146857 SLFN13 MIM:614957|HGNC:HGNC:26481|Ensembl:ENSG00000154760|Vega:OTTHUMG00000165108 +146861 SLC35G3 HGNC:HGNC:26848|Ensembl:ENSG00000164729|Vega:OTTHUMG00000132929 +146862 UNC45B MIM:611220|HGNC:HGNC:14304|Ensembl:ENSG00000141161|Vega:OTTHUMG00000132931 +146880 ARHGAP27P1 HGNC:HGNC:28630|Ensembl:ENSG00000215769 +146894 CD300LG MIM:610520|HGNC:HGNC:30455|Ensembl:ENSG00000161649|Vega:OTTHUMG00000181796 +146909 KIF18B MIM:614570|HGNC:HGNC:27102|Ensembl:ENSG00000186185|Vega:OTTHUMG00000179867 +146923 RUNDC1 HGNC:HGNC:25418|Ensembl:ENSG00000198863|Vega:OTTHUMG00000180659 +146956 EME1 MIM:610885|HGNC:HGNC:24965|Ensembl:ENSG00000154920|Vega:OTTHUMG00000164974 +147004 LOC147004 - +147007 TMEM199 MIM:616815|HGNC:HGNC:18085|Ensembl:ENSG00000244045|Vega:OTTHUMG00000132498 +147011 PROCA1 MIM:617376|HGNC:HGNC:28600|Ensembl:ENSG00000167525|Vega:OTTHUMG00000132682 +147015 DHRS13 MIM:616157|HGNC:HGNC:28326|Ensembl:ENSG00000167536|Vega:OTTHUMG00000132678 +147040 KCTD11 MIM:609848|HGNC:HGNC:21302|Ensembl:ENSG00000213859|Vega:OTTHUMG00000132061 +147081 LINC02210 HGNC:HGNC:26327|Ensembl:ENSG00000204650 +147093 LINC00974 HGNC:HGNC:27105|Ensembl:ENSG00000226629 +147111 NOTUM MIM:609847|HGNC:HGNC:27106|Ensembl:ENSG00000185269|Vega:OTTHUMG00000154416 +147138 TMC8 MIM:605829|HGNC:HGNC:20474|Ensembl:ENSG00000167895|Vega:OTTHUMG00000177436 +147150 UPF3AP2 HGNC:HGNC:30567 +147166 TRIM16L HGNC:HGNC:32670|Ensembl:ENSG00000108448|Vega:OTTHUMG00000059050 +147172 LRRC37BP1 HGNC:HGNC:25390 +147179 WIPF2 MIM:609692|HGNC:HGNC:30923|Ensembl:ENSG00000171475|Vega:OTTHUMG00000133331 +147183 KRT25 MIM:616646|HGNC:HGNC:30839|Ensembl:ENSG00000204897|Vega:OTTHUMG00000133373 +147184 TMEM99 HGNC:HGNC:28305|Ensembl:ENSG00000167920|Vega:OTTHUMG00000133579 +147199 SCGB1C1 MIM:610176|HGNC:HGNC:18394|Ensembl:ENSG00000188076|Vega:OTTHUMG00000165539 +147226 UPF3AP1 HGNC:HGNC:30568 +147228 KRT17P1 HGNC:HGNC:6428 +147276 C18orf15 HGNC:HGNC:26447 +147323 STARD6 MIM:607051|HGNC:HGNC:18066|Ensembl:ENSG00000174448|Vega:OTTHUMG00000132702 +147339 C18orf25 HGNC:HGNC:28172|Ensembl:ENSG00000152242|Vega:OTTHUMG00000179190 +147372 CCBE1 MIM:612753|HGNC:HGNC:29426|Ensembl:ENSG00000183287|Vega:OTTHUMG00000180087 +147381 CBLN2 MIM:600433|HGNC:HGNC:1544|Ensembl:ENSG00000141668|Vega:OTTHUMG00000132825 +147407 SLC25A52 MIM:616153|HGNC:HGNC:23324|Ensembl:ENSG00000141437|Vega:OTTHUMG00000179617 +147409 DSG4 MIM:607892|HGNC:HGNC:21307|Ensembl:ENSG00000175065|Vega:OTTHUMG00000131979 +147429 AQP4-AS1 HGNC:HGNC:26399 +147463 ANKRD29 HGNC:HGNC:27110|Ensembl:ENSG00000154065|Vega:OTTHUMG00000131875 +147468 WBP2P1 HGNC:HGNC:31695 +147495 APCDD1 MIM:607479|HGNC:HGNC:15718|Ensembl:ENSG00000154856|Vega:OTTHUMG00000131635 +147525 LINC00526 HGNC:HGNC:28278 +147645 VSIG10L HGNC:HGNC:27111|Ensembl:ENSG00000186806|Vega:OTTHUMG00000182975 +147646 C19orf84 HGNC:HGNC:27112|Ensembl:ENSG00000262874|Vega:OTTHUMG00000177322 +147650 SPACA6 HGNC:HGNC:27113|Ensembl:ENSG00000182310|Vega:OTTHUMG00000177373 +147657 ZNF480 MIM:613910|HGNC:HGNC:23305|Ensembl:ENSG00000198464|Vega:OTTHUMG00000157507 +147658 ZNF534 HGNC:HGNC:26337|Ensembl:ENSG00000198633|Vega:OTTHUMG00000156493 +147660 ZNF578 HGNC:HGNC:26449|Ensembl:ENSG00000258405|Vega:OTTHUMG00000156468 +147664 ERVV-1 HGNC:HGNC:26501|Ensembl:ENSG00000269526|Vega:OTTHUMG00000182942 +147670 SMIM17 HGNC:HGNC:27114|Ensembl:ENSG00000268182|Vega:OTTHUMG00000177861 +147685 C19orf18 HGNC:HGNC:28642|Ensembl:ENSG00000177025|Vega:OTTHUMG00000183450 +147686 ZNF418 HGNC:HGNC:20647|Ensembl:ENSG00000196724|Vega:OTTHUMG00000183448 +147687 ZNF417 HGNC:HGNC:20646|Ensembl:ENSG00000173480|Vega:OTTHUMG00000183488 +147694 ZNF548 HGNC:HGNC:26561|Ensembl:ENSG00000188785|Vega:OTTHUMG00000183281 +147699 PPM1N HGNC:HGNC:26845|Ensembl:ENSG00000213889|Vega:OTTHUMG00000140397 +147700 KLC3 MIM:601334|HGNC:HGNC:20717|Ensembl:ENSG00000104892|Vega:OTTHUMG00000143722 +147710 IGSF23 HGNC:HGNC:40040|Ensembl:ENSG00000216588|Vega:OTTHUMG00000151531 +147711 ZNF285B HGNC:HGNC:33262 +147719 LYPD4 HGNC:HGNC:28659|Ensembl:ENSG00000273111|Vega:OTTHUMG00000182674 +147727 ILF3-AS1 HGNC:HGNC:27115|Ensembl:ENSG00000267100 +147741 ZNF560 HGNC:HGNC:26484|Ensembl:ENSG00000198028|Vega:OTTHUMG00000180130 +147744 TMEM190 HGNC:HGNC:29632|Ensembl:ENSG00000160472|Vega:OTTHUMG00000180794 +147746 HIPK4 MIM:611712|HGNC:HGNC:19007|Ensembl:ENSG00000160396|Vega:OTTHUMG00000182598 +147798 TMC4 MIM:617181|HGNC:HGNC:22998|Ensembl:ENSG00000167608|Vega:OTTHUMG00000066485 +147804 TPM3P9 HGNC:HGNC:44142|Ensembl:ENSG00000241015 +147807 ZNF524 HGNC:HGNC:28322|Ensembl:ENSG00000171443|Vega:OTTHUMG00000180859 +147808 ZNF784 HGNC:HGNC:33111|Ensembl:ENSG00000179922|Vega:OTTHUMG00000180860 +147837 ZNF563 HGNC:HGNC:30498|Ensembl:ENSG00000188868|Vega:OTTHUMG00000156413 +147841 SPC24 MIM:609394|HGNC:HGNC:26913|Ensembl:ENSG00000161888|Vega:OTTHUMG00000180798 +147872 CCDC155 HGNC:HGNC:26520|Ensembl:ENSG00000161609|Vega:OTTHUMG00000183170 +147906 DACT3 MIM:611112|HGNC:HGNC:30745|Ensembl:ENSG00000197380|Vega:OTTHUMG00000153070 +147912 SIX5 MIM:600963|HGNC:HGNC:10891|Ensembl:ENSG00000177045|Vega:OTTHUMG00000172208 +147920 IGFL2 MIM:610545|HGNC:HGNC:32929|Ensembl:ENSG00000204866|Vega:OTTHUMG00000182492 +147923 ZNF420 MIM:617216|HGNC:HGNC:20649|Ensembl:ENSG00000197050|Vega:OTTHUMG00000048168 +147929 ZNF565 MIM:614275|HGNC:HGNC:26726|Ensembl:ENSG00000196357|Vega:OTTHUMG00000180508 +147945 NLRP4 MIM:609645|HGNC:HGNC:22943|Ensembl:ENSG00000160505|Vega:OTTHUMG00000181734 +147947 ZNF542P HGNC:HGNC:25393|Ensembl:ENSG00000240225 +147948 ZNF582 MIM:615600|HGNC:HGNC:26421|Ensembl:ENSG00000018869|Vega:OTTHUMG00000181939 +147949 ZNF583 HGNC:HGNC:26427|Ensembl:ENSG00000198440|Vega:OTTHUMG00000168874 +147965 FAM98C HGNC:HGNC:27119|Ensembl:ENSG00000130244|Vega:OTTHUMG00000182084 +147968 CAPN12 MIM:608839|HGNC:HGNC:13249|Ensembl:ENSG00000182472|Vega:OTTHUMG00000182525 +147991 DPY19L3 MIM:613894|HGNC:HGNC:27120|Ensembl:ENSG00000178904|Vega:OTTHUMG00000180222 +148003 LGALS16 HGNC:HGNC:40039|Ensembl:ENSG00000249861|Vega:OTTHUMG00000183083 +148014 TTC9B HGNC:HGNC:26395|Ensembl:ENSG00000174521|Vega:OTTHUMG00000182600 +148022 TICAM1 MIM:607601|HGNC:HGNC:18348|Ensembl:ENSG00000127666|Vega:OTTHUMG00000180248 +148046 CIRBP-AS1 HGNC:HGNC:28588 +148066 ZNRF4 MIM:612063|HGNC:HGNC:17726|Ensembl:ENSG00000105428|Vega:OTTHUMG00000180356 +148103 ZNF599 HGNC:HGNC:26408|Ensembl:ENSG00000153896|Vega:OTTHUMG00000182346 +148109 FAM187B HGNC:HGNC:26366|Ensembl:ENSG00000177558|Vega:OTTHUMG00000164450 +148113 CILP2 MIM:612419|HGNC:HGNC:24213|Ensembl:ENSG00000160161|Vega:OTTHUMG00000182148 +148137 PROSER3 HGNC:HGNC:25204|Ensembl:ENSG00000167595|Vega:OTTHUMG00000168103 +148145 LINC00906 HGNC:HGNC:27121|Ensembl:ENSG00000267339 +148156 ZNF558 HGNC:HGNC:26422|Ensembl:ENSG00000167785|Vega:OTTHUMG00000182196 +148170 CDC42EP5 MIM:609171|HGNC:HGNC:17408|Ensembl:ENSG00000167617|Vega:OTTHUMG00000065699 +148189 LINC00662 HGNC:HGNC:27122|Ensembl:ENSG00000261824 +148198 ZNF98 MIM:603980|HGNC:HGNC:13174|Ensembl:ENSG00000197360|Vega:OTTHUMG00000182940 +148203 ZNF738 HGNC:HGNC:32469 +148206 ZNF714 HGNC:HGNC:27124|Ensembl:ENSG00000160352|Vega:OTTHUMG00000182833 +148213 ZNF681 HGNC:HGNC:26457|Ensembl:ENSG00000196172|Vega:OTTHUMG00000150831 +148223 C19orf25 HGNC:HGNC:26711|Ensembl:ENSG00000119559|Vega:OTTHUMG00000180092 +148229 ATP8B3 MIM:605866|HGNC:HGNC:13535|Ensembl:ENSG00000130270|Vega:OTTHUMG00000166189 +148231 LINC00905 HGNC:HGNC:26334|Ensembl:ENSG00000167459 +148252 DIRAS1 MIM:607862|HGNC:HGNC:19127|Ensembl:ENSG00000176490|Vega:OTTHUMG00000180439 +148254 ZNF555 HGNC:HGNC:28382|Ensembl:ENSG00000186300|Vega:OTTHUMG00000180500 +148266 ZNF569 MIM:613904|HGNC:HGNC:24737|Ensembl:ENSG00000196437|Vega:OTTHUMG00000048172 +148268 ZNF570 HGNC:HGNC:26416|Ensembl:ENSG00000171827|Vega:OTTHUMG00000048176 +148281 SYT6 MIM:607718|HGNC:HGNC:18638|Ensembl:ENSG00000134207|Vega:OTTHUMG00000011755 +148300 SONP1 HGNC:HGNC:30608 +148304 C1orf74 HGNC:HGNC:26319|Ensembl:ENSG00000162757|Vega:OTTHUMG00000036483 +148327 CREB3L4 MIM:607138|HGNC:HGNC:18854|Ensembl:ENSG00000143578|Vega:OTTHUMG00000037159 +148330 MRPS33P1 HGNC:HGNC:29764 +148345 C1orf127 HGNC:HGNC:26730|Ensembl:ENSG00000175262|Vega:OTTHUMG00000002032 +148362 BROX HGNC:HGNC:26512|Ensembl:ENSG00000162819|Vega:OTTHUMG00000037650 +148398 SAMD11 MIM:616765|HGNC:HGNC:28706|Ensembl:ENSG00000187634|Vega:OTTHUMG00000040719 +148413 LOC148413 Ensembl:ENSG00000224870 +148418 SAMD13 HGNC:HGNC:24582|Ensembl:ENSG00000203943|Vega:OTTHUMG00000009859 +148423 C1orf52 HGNC:HGNC:24871|Ensembl:ENSG00000162642|Vega:OTTHUMG00000009966 +148430 LOC148430 - +148479 PHF13 HGNC:HGNC:22983|Ensembl:ENSG00000116273|Vega:OTTHUMG00000001439 +148523 CIART MIM:615782|HGNC:HGNC:25200|Ensembl:ENSG00000159208|Vega:OTTHUMG00000012548 +148534 TMEM56 HGNC:HGNC:26477|Ensembl:ENSG00000152078|Vega:OTTHUMG00000010847 +148545 NBPF4 MIM:613994|HGNC:HGNC:26550|Ensembl:ENSG00000196427|Vega:OTTHUMG00000011318 +148581 UBE2U HGNC:HGNC:28559|Ensembl:ENSG00000177414|Vega:OTTHUMG00000009023 +148641 SLC35F3 HGNC:HGNC:23616|Ensembl:ENSG00000183780|Vega:OTTHUMG00000037929 +148645 LINC00337 HGNC:HGNC:28620 +148696 LOC148696 - +148709 LOC148709 Ensembl:ENSG00000234996 +148713 PTPRVP HGNC:HGNC:13421|Ensembl:ENSG00000243323 +148738 HFE2 MIM:608374|HGNC:HGNC:4887|Ensembl:ENSG00000168509|Vega:OTTHUMG00000013748 +148741 ANKRD35 HGNC:HGNC:26323|Ensembl:ENSG00000198483|Vega:OTTHUMG00000013743 +148753 FAM163A MIM:611727|HGNC:HGNC:28274|Ensembl:ENSG00000143340|Vega:OTTHUMG00000035262 +148756 OVAAL HGNC:HGNC:49422|Ensembl:ENSG00000236719 +148789 B3GALNT2 MIM:610194|HGNC:HGNC:28596|Ensembl:ENSG00000162885|Vega:OTTHUMG00000040468 +148808 MFSD4A HGNC:HGNC:25433|Ensembl:ENSG00000174514|Vega:OTTHUMG00000037197 +148811 PM20D1 MIM:617124|HGNC:HGNC:26518|Ensembl:ENSG00000162877|Vega:OTTHUMG00000035999 +148818 HSD17B7P1 HGNC:HGNC:18689 +148823 GCSAML HGNC:HGNC:29583|Ensembl:ENSG00000169224|Vega:OTTHUMG00000040648 +148824 GCSAML-AS1 HGNC:HGNC:41244 +148867 SLC30A7 MIM:611149|HGNC:HGNC:19306|Ensembl:ENSG00000162695|Vega:OTTHUMG00000011815 +148870 CCDC27 HGNC:HGNC:26546|Ensembl:ENSG00000162592|Vega:OTTHUMG00000003504 +148898 ZNF436-AS1 HGNC:HGNC:25122|Ensembl:ENSG00000249087 +148930 KNCN MIM:611455|HGNC:HGNC:26488|Ensembl:ENSG00000162456|Vega:OTTHUMG00000007987 +148932 MOB3C HGNC:HGNC:29800|Ensembl:ENSG00000142961|Vega:OTTHUMG00000007989 +148979 GLIS1 MIM:610378|HGNC:HGNC:29525|Ensembl:ENSG00000174332|Vega:OTTHUMG00000008079 +149013 NBPF12 MIM:608607|HGNC:HGNC:24297|Ensembl:ENSG00000268043|Vega:OTTHUMG00000043708 +149018 LELP1 MIM:611042|HGNC:HGNC:32046|Ensembl:ENSG00000203784|Vega:OTTHUMG00000013935 +149041 RC3H1 MIM:609424|HGNC:HGNC:29434|Ensembl:ENSG00000135870|Vega:OTTHUMG00000037275 +149047 MGC27382 Ensembl:ENSG00000237413 +149069 DCDC2B HGNC:HGNC:32576|Ensembl:ENSG00000222046|Vega:OTTHUMG00000005741 +149076 ZNF362 HGNC:HGNC:18079|Ensembl:ENSG00000160094|Vega:OTTHUMG00000004124 +149086 LINC01225 HGNC:HGNC:49677|Ensembl:ENSG00000260386 +149095 DCST1 HGNC:HGNC:26539|Ensembl:ENSG00000163357|Vega:OTTHUMG00000041314 +149111 CNIH3 HGNC:HGNC:26802|Ensembl:ENSG00000143786|Vega:OTTHUMG00000037634 +149134 LINC01341 HGNC:HGNC:49457 +149175 MANEAL HGNC:HGNC:26452|Ensembl:ENSG00000185090|Vega:OTTHUMG00000004317 +149224 RPS7P4 HGNC:HGNC:36000 +149233 IL23R MIM:607562|HGNC:HGNC:19100|Ensembl:ENSG00000162594|Vega:OTTHUMG00000009092 +149281 METTL11B HGNC:HGNC:31932|Ensembl:ENSG00000203740|Vega:OTTHUMG00000035959 +149297 FAM78B HGNC:HGNC:13495|Ensembl:ENSG00000188859|Vega:OTTHUMG00000034705 +149345 SHISA4 MIM:617326|HGNC:HGNC:27139|Ensembl:ENSG00000198892|Vega:OTTHUMG00000035807 +149371 EXOC8 MIM:615283|HGNC:HGNC:24659|Ensembl:ENSG00000116903|Vega:OTTHUMG00000038025 +149373 LOC149373 - +149420 PDIK1L MIM:610785|HGNC:HGNC:18981|Ensembl:ENSG00000175087|Vega:OTTHUMG00000007511 +149428 BNIPL MIM:611275|HGNC:HGNC:16976|Ensembl:ENSG00000163141|Vega:OTTHUMG00000035157 +149461 CLDN19 MIM:610036|HGNC:HGNC:2040|Ensembl:ENSG00000164007|Vega:OTTHUMG00000007524 +149465 CFAP57 MIM:614259|HGNC:HGNC:26485|Ensembl:ENSG00000243710|Vega:OTTHUMG00000007285 +149466 C1orf210 HGNC:HGNC:28755|Ensembl:ENSG00000253313|Vega:OTTHUMG00000007289 +149473 CCDC24 HGNC:HGNC:28688|Ensembl:ENSG00000159214|Vega:OTTHUMG00000008299 +149478 BTBD19 HGNC:HGNC:27145|Ensembl:ENSG00000222009|Vega:OTTHUMG00000008493 +149483 CCDC17 HGNC:HGNC:26574|Ensembl:ENSG00000159588|Vega:OTTHUMG00000007822 +149499 LRRC71 HGNC:HGNC:26556|Ensembl:ENSG00000160838|Vega:OTTHUMG00000041298 +149501 KRT8P45 HGNC:HGNC:39879 +149563 C1orf64 HGNC:HGNC:28339|Ensembl:ENSG00000183888|Vega:OTTHUMG00000009523 +149603 RNF187 MIM:613754|HGNC:HGNC:27146|Ensembl:ENSG00000168159|Vega:OTTHUMG00000040043 +149620 CHIAP2 HGNC:HGNC:44463|Ensembl:ENSG00000203878 +149628 PYHIN1 MIM:612677|HGNC:HGNC:28894|Ensembl:ENSG00000163564|Vega:OTTHUMG00000037109 +149643 SPATA45 HGNC:HGNC:33709|Ensembl:ENSG00000185523|Vega:OTTHUMG00000036920 +149647 FAM71A HGNC:HGNC:26541|Ensembl:ENSG00000162771|Vega:OTTHUMG00000041084 +149684 LOC149684 Ensembl:ENSG00000101425|Vega:OTTHUMG00000032441 +149685 ADIG MIM:611396|HGNC:HGNC:28606|Ensembl:ENSG00000182035|Vega:OTTHUMG00000032451 +149699 GTSF1L HGNC:HGNC:16198|Ensembl:ENSG00000124196|Vega:OTTHUMG00000032510 +149708 WFDC5 MIM:605161|HGNC:HGNC:20477|Ensembl:ENSG00000175121|Vega:OTTHUMG00000046411 +149773 APCDD1L-AS1 HGNC:HGNC:27152|Ensembl:ENSG00000231290 +149775 GNAS-AS1 MIM:610540|HGNC:HGNC:24872|Ensembl:ENSG00000235590 +149830 PRNT HGNC:HGNC:18046|Ensembl:ENSG00000180259|Vega:OTTHUMG00000031785 +149837 LINC00654 HGNC:HGNC:27154|Ensembl:ENSG00000205181 +149840 C20orf196 HGNC:HGNC:26318|Ensembl:ENSG00000171984|Vega:OTTHUMG00000031813 +149844 LOC149844 - +149934 NCOR1P1 HGNC:HGNC:16724|Ensembl:ENSG00000240108 +149935 LOC149935 - +149950 LOC149950 Ensembl:ENSG00000204393 +149951 COMMD7 MIM:616703|HGNC:HGNC:16223|Ensembl:ENSG00000149600|Vega:OTTHUMG00000032229 +149954 BPIFB4 MIM:615718|HGNC:HGNC:16179|Ensembl:ENSG00000186191|Vega:OTTHUMG00000032235 +149986 LSM14B HGNC:HGNC:15887|Ensembl:ENSG00000149657|Vega:OTTHUMG00000032901 +149992 ANKRD30BP2 HGNC:HGNC:16620 +149998 LIPI MIM:609252|HGNC:HGNC:18821|Ensembl:ENSG00000188992|Vega:OTTHUMG00000074258 +150000 ABCC13 MIM:608835|HGNC:HGNC:16022|Ensembl:ENSG00000243064 +150051 LOC150051 Vega:OTTHUMG00000186474 +150082 LCA5L HGNC:HGNC:1255|Ensembl:ENSG00000157578|Vega:OTTHUMG00000066280 +150084 IGSF5 MIM:610638|HGNC:HGNC:5952|Ensembl:ENSG00000183067|Vega:OTTHUMG00000086724 +150094 SIK1 MIM:605705|HGNC:HGNC:11142|Ensembl:ENSG00000142178|Vega:OTTHUMG00000086874 +150135 LINC00479 HGNC:HGNC:19727|Ensembl:ENSG00000236384 +150142 ZNF295-AS1 HGNC:HGNC:23130|Ensembl:ENSG00000237232 +150147 UMODL1-AS1 HGNC:HGNC:23821|Ensembl:ENSG00000184385 +150159 SLC9B1 MIM:611527|HGNC:HGNC:24244|Ensembl:ENSG00000164037|Vega:OTTHUMG00000161114 +150160 CCT8L2 HGNC:HGNC:15553|Ensembl:ENSG00000198445|Vega:OTTHUMG00000141302 +150165 XKR3 MIM:611674|HGNC:HGNC:28778|Ensembl:ENSG00000172967|Vega:OTTHUMG00000143726 +150185 LINC00895 HGNC:HGNC:48580 +150197 LINC00896 HGNC:HGNC:26519|Ensembl:ENSG00000236499 +150209 AIFM3 MIM:617298|HGNC:HGNC:26398|Ensembl:ENSG00000183773|Vega:OTTHUMG00000150804 +150221 RIMBP3C MIM:612701|HGNC:HGNC:33892|Ensembl:ENSG00000183246|Vega:OTTHUMG00000150825 +150223 YDJC HGNC:HGNC:27158|Ensembl:ENSG00000161179|Vega:OTTHUMG00000150822 +150244 ZDHHC8P1 HGNC:HGNC:26461 +150248 C22orf15 HGNC:HGNC:15558|Ensembl:ENSG00000169314|Vega:OTTHUMG00000150740 +150274 HSCB MIM:608142|HGNC:HGNC:28913|Ensembl:ENSG00000100209|Vega:OTTHUMG00000151092 +150275 CCDC117 HGNC:HGNC:26599|Ensembl:ENSG00000159873|Vega:OTTHUMG00000151091 +150280 HORMAD2 HGNC:HGNC:28383|Ensembl:ENSG00000176635|Vega:OTTHUMG00000150881 +150290 DUSP18 MIM:611446|HGNC:HGNC:18484|Ensembl:ENSG00000167065|Vega:OTTHUMG00000151115 +150291 MORC2-AS1 HGNC:HGNC:26662|Ensembl:ENSG00000235989 +150297 C22orf42 HGNC:HGNC:27160|Ensembl:ENSG00000205856|Vega:OTTHUMG00000030380 +150350 ENTHD1 HGNC:HGNC:26352|Ensembl:ENSG00000176177|Vega:OTTHUMG00000151098 +150353 DNAJB7 MIM:611336|HGNC:HGNC:24986|Ensembl:ENSG00000172404|Vega:OTTHUMG00000151202 +150356 CHADL MIM:616236|HGNC:HGNC:25165|Ensembl:ENSG00000100399|Vega:OTTHUMG00000150936 +150365 MEI1 MIM:608797|HGNC:HGNC:28613|Ensembl:ENSG00000167077|Vega:OTTHUMG00000030083 +150368 FAM109B MIM:614240|HGNC:HGNC:27161|Ensembl:ENSG00000177096|Vega:OTTHUMG00000151285 +150372 NFAM1 MIM:608740|HGNC:HGNC:29872|Ensembl:ENSG00000235568|Vega:OTTHUMG00000150923 +150378 FLJ30901 - +150379 PNPLA5 MIM:611589|HGNC:HGNC:24888|Ensembl:ENSG00000100341|Vega:OTTHUMG00000030779 +150381 PRR34-AS1 HGNC:HGNC:50499 +150383 CDPF1 HGNC:HGNC:33710|Ensembl:ENSG00000205643|Vega:OTTHUMG00000030672 +150384 GTSE1-AS1 HGNC:HGNC:27163|Ensembl:ENSG00000277232 +150417 LOC150417 - +150465 TTL MIM:608291|HGNC:HGNC:21586|Ensembl:ENSG00000114999|Vega:OTTHUMG00000131316 +150468 CKAP2L MIM:616174|HGNC:HGNC:26877|Ensembl:ENSG00000169607|Vega:OTTHUMG00000131313 +150472 CBWD2 MIM:611079|HGNC:HGNC:17907|Ensembl:ENSG00000136682|Vega:OTTHUMG00000131360 +150478 bA395L14.12 - +150483 TEKT4 HGNC:HGNC:31012|Ensembl:ENSG00000163060|Vega:OTTHUMG00000130396 +150527 TISP43 Ensembl:ENSG00000183292 +150538 SATB2-AS1 HGNC:HGNC:26490|Ensembl:ENSG00000225953 +150554 YWHAZP2 HGNC:HGNC:31078 +150568 LINC01102 HGNC:HGNC:27165|Ensembl:ENSG00000235597 +150572 SMYD1 MIM:606846|HGNC:HGNC:20986|Ensembl:ENSG00000115593|Vega:OTTHUMG00000155045 +150577 LINC01104 HGNC:HGNC:49226|Ensembl:ENSG00000232084 +150590 C2orf15 HGNC:HGNC:28436|Ensembl:ENSG00000273045|Vega:OTTHUMG00000130635 +150596 LINC01931 HGNC:HGNC:52743 +150622 LINC01105 HGNC:HGNC:26403 +150677 OTOS MIM:607877|HGNC:HGNC:22644|Ensembl:ENSG00000178602|Vega:OTTHUMG00000133351 +150678 COPS9 HGNC:HGNC:21314|Ensembl:ENSG00000172428|Vega:OTTHUMG00000133352 +150681 OR6B3 HGNC:HGNC:15042|Ensembl:ENSG00000178586|Vega:OTTHUMG00000152399 +150684 COMMD1 MIM:607238|HGNC:HGNC:23024|Ensembl:ENSG00000173163|Vega:OTTHUMG00000129445 +150696 PROM2 MIM:617160|HGNC:HGNC:20685|Ensembl:ENSG00000155066|Vega:OTTHUMG00000130393 +150709 ANKAR MIM:609803|HGNC:HGNC:26350|Ensembl:ENSG00000151687|Vega:OTTHUMG00000154398 +150726 FBXO41 MIM:609108|HGNC:HGNC:29409|Ensembl:ENSG00000163013|Vega:OTTHUMG00000164127 +150737 TTC30B HGNC:HGNC:26425|Ensembl:ENSG00000196659|Vega:OTTHUMG00000154166 +150759 LINC00342 HGNC:HGNC:42470 +150763 GPAT2 MIM:616431|HGNC:HGNC:27168|Ensembl:ENSG00000186281|Vega:OTTHUMG00000155208 +150771 ITPRIPL1 HGNC:HGNC:29371|Ensembl:ENSG00000198885|Vega:OTTHUMG00000155230 +150776 LOC150776 Ensembl:ENSG00000152117 +150786 WTH3DI Ensembl:ENSG00000233087|Vega:OTTHUMG00000153556 +150864 FAM117B HGNC:HGNC:14440|Ensembl:ENSG00000138439|Vega:OTTHUMG00000154550 +150921 TCF23 MIM:609635|HGNC:HGNC:18602|Ensembl:ENSG00000163792|Vega:OTTHUMG00000152031 +150928 PTMAP5 HGNC:HGNC:9628 +150935 LOC150935 - +150946 GAREM2 HGNC:HGNC:27172|Ensembl:ENSG00000157833|Vega:OTTHUMG00000151935 +150947 PPIL1P1 HGNC:HGNC:20865 +150962 PUS10 MIM:612787|HGNC:HGNC:26505|Ensembl:ENSG00000162927|Vega:OTTHUMG00000129423 +150967 LINC01963 HGNC:HGNC:25283|Ensembl:ENSG00000260804 +150992 LINC00309 HGNC:HGNC:25279|Ensembl:ENSG00000230923 +151009 LINC01106 HGNC:HGNC:26769 +151011 SEPT10 MIM:611737|HGNC:HGNC:14349|Ensembl:ENSG00000186522|Vega:OTTHUMG00000154957 +151050 KANSL1L MIM:613833|HGNC:HGNC:26310|Ensembl:ENSG00000144445|Vega:OTTHUMG00000154697 +151056 PLB1 MIM:610179|HGNC:HGNC:30041|Ensembl:ENSG00000163803|Vega:OTTHUMG00000152014 +151112 ZSWIM2 HGNC:HGNC:30990|Ensembl:ENSG00000163012|Vega:OTTHUMG00000154259 +151121 LINC01854 HGNC:HGNC:52670|Ensembl:ENSG00000204460 +151126 ZNF385B MIM:612344|HGNC:HGNC:26332|Ensembl:ENSG00000144331|Vega:OTTHUMG00000154559 +151171 LINC01107 HGNC:HGNC:49229|Ensembl:ENSG00000225493 +151174 LOC151174 Ensembl:ENSG00000186235 +151176 ERFE MIM:615099|HGNC:HGNC:26727|Ensembl:ENSG00000178752|Vega:OTTHUMG00000152901 +151188 ARL6IP6 MIM:616495|HGNC:HGNC:24048|Ensembl:ENSG00000177917|Vega:OTTHUMG00000131901 +151194 METTL21A MIM:615257|HGNC:HGNC:30476|Ensembl:ENSG00000144401|Vega:OTTHUMG00000132934 +151195 CCNYL1 HGNC:HGNC:26868|Ensembl:ENSG00000163249|Vega:OTTHUMG00000132946 +151230 KLHL23 HGNC:HGNC:27506|Ensembl:ENSG00000213160|Vega:OTTHUMG00000132213 +151234 SULT1C2P1 HGNC:HGNC:33545|Ensembl:ENSG00000237223 +151242 PPP1R1C MIM:613240|HGNC:HGNC:14940|Ensembl:ENSG00000150722|Vega:OTTHUMG00000154326 +151246 SGO2 MIM:612425|HGNC:HGNC:30812|Ensembl:ENSG00000163535|Vega:OTTHUMG00000154535 +151254 C2CD6 HGNC:HGNC:14438|Ensembl:ENSG00000155754|Vega:OTTHUMG00000132830 +151258 SLC38A11 MIM:616526|HGNC:HGNC:26836|Ensembl:ENSG00000169507|Vega:OTTHUMG00000132144 +151276 TXNP5 HGNC:HGNC:49485 +151278 CCDC140 HGNC:HGNC:26514|Ensembl:ENSG00000163081|Vega:OTTHUMG00000133154 +151295 SLC23A3 HGNC:HGNC:20601|Ensembl:ENSG00000213901|Vega:OTTHUMG00000154616 +151300 LINC00608 HGNC:HGNC:27179 +151306 GPBAR1 MIM:610147|HGNC:HGNC:19680|Ensembl:ENSG00000179921|Vega:OTTHUMG00000155203 +151313 FAHD2B HGNC:HGNC:25318|Ensembl:ENSG00000144199|Vega:OTTHUMG00000130533 +151325 MYADML HGNC:HGNC:31019|Ensembl:ENSG00000239649 +151354 FAM84A MIM:611234|HGNC:HGNC:20743|Ensembl:ENSG00000162981|Vega:OTTHUMG00000119093 +151393 RMDN2 MIM:611872|HGNC:HGNC:26567|Ensembl:ENSG00000115841|Vega:OTTHUMG00000128487 +151449 GDF7 MIM:604651|HGNC:HGNC:4222|Ensembl:ENSG00000143869|Vega:OTTHUMG00000090781 +151457 LOC151457 - +151473 SLC16A14 HGNC:HGNC:26417|Ensembl:ENSG00000163053|Vega:OTTHUMG00000133205 +151475 LINC01907 HGNC:HGNC:52726|Ensembl:ENSG00000226125 +151477 LINC00471 HGNC:HGNC:28668|Ensembl:ENSG00000181798 +151484 LOC151484 Ensembl:ENSG00000232520 +151507 MSL3P1 HGNC:HGNC:17837|Ensembl:ENSG00000224287 +151516 ASPRV1 MIM:611765|HGNC:HGNC:26321|Ensembl:ENSG00000244617|Vega:OTTHUMG00000129647 +151525 WDSUB1 HGNC:HGNC:26697|Ensembl:ENSG00000196151|Vega:OTTHUMG00000132028 +151531 UPP2 MIM:617340|HGNC:HGNC:23061|Ensembl:ENSG00000007001|Vega:OTTHUMG00000131969 +151534 LBX2-AS1 HGNC:HGNC:25136|Ensembl:ENSG00000257702 +151556 GPR155 HGNC:HGNC:22951|Ensembl:ENSG00000163328|Vega:OTTHUMG00000132336 +151579 BZW1P2 HGNC:HGNC:33954 +151613 TTC14 HGNC:HGNC:24697|Ensembl:ENSG00000163728|Vega:OTTHUMG00000157859 +151636 DTX3L MIM:613143|HGNC:HGNC:30323|Ensembl:ENSG00000163840|Vega:OTTHUMG00000159524 +151645 PSMC1P1 HGNC:HGNC:30147 +151647 FAM19A4 MIM:617498|HGNC:HGNC:21591|Ensembl:ENSG00000163377|Vega:OTTHUMG00000158744 +151648 SGO1 MIM:609168|HGNC:HGNC:25088|Ensembl:ENSG00000129810|Vega:OTTHUMG00000130479 +151649 PP2D1 HGNC:HGNC:28406|Ensembl:ENSG00000183977|Vega:OTTHUMG00000155393 +151651 EFHB HGNC:HGNC:26330|Ensembl:ENSG00000163576|Vega:OTTHUMG00000150505 +151658 LINC00635 HGNC:HGNC:27184|Ensembl:ENSG00000241469 +151742 PPM1L MIM:611931|HGNC:HGNC:16381|Ensembl:ENSG00000163590|Vega:OTTHUMG00000159048 +151760 LOC151760 - +151790 WDR49 HGNC:HGNC:26587|Ensembl:ENSG00000174776|Vega:OTTHUMG00000158290 +151825 KRT18P43 HGNC:HGNC:33413 +151827 LRRC34 HGNC:HGNC:28408|Ensembl:ENSG00000171757|Vega:OTTHUMG00000164419 +151835 CPNE9 HGNC:HGNC:24336|Ensembl:ENSG00000144550|Vega:OTTHUMG00000128418 +151842 PP1P HGNC:HGNC:28884 +151871 DPPA2 MIM:614445|HGNC:HGNC:19197|Ensembl:ENSG00000163530|Vega:OTTHUMG00000159227 +151877 MAGI1-IT1 HGNC:HGNC:42436 +151887 CCDC80 MIM:608298|HGNC:HGNC:30649|Ensembl:ENSG00000091986|Vega:OTTHUMG00000159265 +151888 BTLA MIM:607925|HGNC:HGNC:21087|Ensembl:ENSG00000186265|Vega:OTTHUMG00000159255 +151903 CCDC12 HGNC:HGNC:28332|Ensembl:ENSG00000160799|Vega:OTTHUMG00000133513 +151963 MB21D2 HGNC:HGNC:30438|Ensembl:ENSG00000180611|Vega:OTTHUMG00000155768 +151987 PPP4R2 MIM:613822|HGNC:HGNC:18296|Ensembl:ENSG00000163605|Vega:OTTHUMG00000158816 +152002 XXYLT1 MIM:614552|HGNC:HGNC:26639|Ensembl:ENSG00000173950|Vega:OTTHUMG00000155915 +152006 RNF38 MIM:612488|HGNC:HGNC:18052|Ensembl:ENSG00000137075|Vega:OTTHUMG00000019905 +152007 GLIPR2 MIM:607141|HGNC:HGNC:18007|Ensembl:ENSG00000122694|Vega:OTTHUMG00000019900 +152015 ROPN1B HGNC:HGNC:31927|Ensembl:ENSG00000114547|Vega:OTTHUMG00000162651 +152024 LINC00691 HGNC:HGNC:44514|Ensembl:ENSG00000224074 +152048 LOC152048 - +152065 C3orf22 HGNC:HGNC:28534|Ensembl:ENSG00000180697|Vega:OTTHUMG00000162731 +152078 PQLC2L HGNC:HGNC:25146|Ensembl:ENSG00000174899|Vega:OTTHUMG00000158748 +152098 ZCWPW2 HGNC:HGNC:23574|Ensembl:ENSG00000206559|Ensembl:ENSG00000283563|Vega:OTTHUMG00000155705|Vega:OTTHUMG00000191752 +152100 CMC1 MIM:615166|HGNC:HGNC:28783|Ensembl:ENSG00000187118|Vega:OTTHUMG00000155660 +152101 VENTXP4 HGNC:HGNC:30903 +152110 NEK10 HGNC:HGNC:18592|Ensembl:ENSG00000163491|Vega:OTTHUMG00000130571 +152118 C3orf79 HGNC:HGNC:37259 +152137 CCDC50 MIM:611051|HGNC:HGNC:18111|Ensembl:ENSG00000152492|Vega:OTTHUMG00000156177 +152138 PYDC2 MIM:615701|HGNC:HGNC:33512|Ensembl:ENSG00000253548 +152185 SPICE1 MIM:613447|HGNC:HGNC:25083|Ensembl:ENSG00000163611|Vega:OTTHUMG00000159261 +152189 CMTM8 MIM:607891|HGNC:HGNC:19179|Ensembl:ENSG00000170293|Vega:OTTHUMG00000130753 +152195 NUDT16P1 HGNC:HGNC:27189|Ensembl:ENSG00000246082 +152206 CCDC13 HGNC:HGNC:26358|Ensembl:ENSG00000244607|Vega:OTTHUMG00000133046 +152217 NCBP2-AS2 HGNC:HGNC:25121 +152225 LINC02085 HGNC:HGNC:27190|Ensembl:ENSG00000214407|Ensembl:ENSG00000241280 +152273 FGD5 MIM:614788|HGNC:HGNC:19117|Ensembl:ENSG00000154783|Vega:OTTHUMG00000155556 +152274 LINC02011 HGNC:HGNC:27191|Ensembl:ENSG00000260902 +152302 CIDECP HGNC:HGNC:24230|Ensembl:ENSG00000186162 +152330 CNTN4 MIM:607280|HGNC:HGNC:2174|Ensembl:ENSG00000144619|Vega:OTTHUMG00000119031 +152404 IGSF11 MIM:608351|HGNC:HGNC:16669|Ensembl:ENSG00000144847|Vega:OTTHUMG00000159387 +152405 C3orf30 HGNC:HGNC:26553|Ensembl:ENSG00000163424|Vega:OTTHUMG00000159349 +152485 ZNF827 HGNC:HGNC:27193|Ensembl:ENSG00000151612|Vega:OTTHUMG00000161362 +152503 SH3D19 MIM:608674|HGNC:HGNC:30418|Ensembl:ENSG00000109686|Vega:OTTHUMG00000154051 +152518 NFXL1 HGNC:HGNC:18726|Ensembl:ENSG00000170448|Vega:OTTHUMG00000128621 +152519 NIPAL1 HGNC:HGNC:27194|Ensembl:ENSG00000163293|Vega:OTTHUMG00000128622 +152559 PAQR3 MIM:614577|HGNC:HGNC:30130|Ensembl:ENSG00000163291|Vega:OTTHUMG00000161026 +152573 SHISA3 MIM:617325|HGNC:HGNC:25159|Ensembl:ENSG00000178343|Vega:OTTHUMG00000161043 +152578 LINC01618 HGNC:HGNC:27195|Ensembl:ENSG00000250302 +152579 SCFD2 HGNC:HGNC:30676|Ensembl:ENSG00000184178|Vega:OTTHUMG00000160588 +152586 MGAT4D MIM:610310|HGNC:HGNC:43619|Ensembl:ENSG00000205301|Vega:OTTHUMG00000161376 +152594 LOC152594 - +152641 WWC2-AS2 HGNC:HGNC:26390|Ensembl:ENSG00000251359 +152663 RPL7AP27 HGNC:HGNC:36806 +152667 FAM192BP HGNC:HGNC:37194 +152687 ZNF595 HGNC:HGNC:27196|Ensembl:ENSG00000272602|Vega:OTTHUMG00000159865 +152709 ARL4AP2 HGNC:HGNC:32379 +152742 LINC01085 HGNC:HGNC:27198|Ensembl:ENSG00000248698 +152756 FAM218A HGNC:HGNC:26466|Ensembl:ENSG00000250486|Vega:OTTHUMG00000161252 +152789 JAKMIP1 MIM:611195|HGNC:HGNC:26460|Ensembl:ENSG00000152969|Vega:OTTHUMG00000125491 +152815 THAP6 MIM:612535|HGNC:HGNC:23189|Ensembl:ENSG00000174796|Vega:OTTHUMG00000130108 +152816 C4orf26 MIM:614829|HGNC:HGNC:26300|Ensembl:ENSG00000174792|Vega:OTTHUMG00000130104 +152831 KLB MIM:611135|HGNC:HGNC:15527|Ensembl:ENSG00000134962|Vega:OTTHUMG00000128577 +152845 LOC152845 - +152877 FAM53A MIM:617229|HGNC:HGNC:31860|Ensembl:ENSG00000174137|Vega:OTTHUMG00000159855 +152905 RTN3P1 HGNC:HGNC:19212 +152926 PPM1K MIM:611065|HGNC:HGNC:25415|Ensembl:ENSG00000163644|Vega:OTTHUMG00000130952 +152940 C4orf45 HGNC:HGNC:26342|Ensembl:ENSG00000164123|Vega:OTTHUMG00000161988 +152992 TRMT44 MIM:614309|HGNC:HGNC:26653|Ensembl:ENSG00000155275|Vega:OTTHUMG00000160935 +153020 RASGEF1B MIM:614532|HGNC:HGNC:24881|Ensembl:ENSG00000138670|Vega:OTTHUMG00000160890 +153090 DAB2IP MIM:609205|HGNC:HGNC:17294|Ensembl:ENSG00000136848|Vega:OTTHUMG00000020595 +153129 SLC38A9 MIM:616203|HGNC:HGNC:26907|Ensembl:ENSG00000177058|Vega:OTTHUMG00000131189 +153163 MGC32805 Ensembl:ENSG00000250328 +153201 SLC36A2 MIM:608331|HGNC:HGNC:18762|Ensembl:ENSG00000186335|Vega:OTTHUMG00000130129 +153218 SPINK13 MIM:615205|HGNC:HGNC:27200|Ensembl:ENSG00000214510|Vega:OTTHUMG00000163426 +153222 CREBRF MIM:617109|HGNC:HGNC:24050|Ensembl:ENSG00000164463|Vega:OTTHUMG00000163322 +153241 CEP120 MIM:613446|HGNC:HGNC:26690|Ensembl:ENSG00000168944|Vega:OTTHUMG00000128922 +153328 SLC25A48 MIM:616150|HGNC:HGNC:30451|Ensembl:ENSG00000145832|Vega:OTTHUMG00000157007 +153339 TMEM167A HGNC:HGNC:28330|Ensembl:ENSG00000174695|Vega:OTTHUMG00000162570 +153364 MBLAC2 HGNC:HGNC:33711|Ensembl:ENSG00000176055|Vega:OTTHUMG00000131327 +153396 TMEM161B HGNC:HGNC:28483|Ensembl:ENSG00000164180|Vega:OTTHUMG00000131323 +153443 SRFBP1 MIM:610479|HGNC:HGNC:26333|Ensembl:ENSG00000151304|Vega:OTTHUMG00000162970 +153469 JAKMIP2-AS1 HGNC:HGNC:27203|Ensembl:ENSG00000280780 +153478 PLEKHG4B HGNC:HGNC:29399|Ensembl:ENSG00000153404|Vega:OTTHUMG00000161570 +153527 ZMAT2 HGNC:HGNC:26433|Ensembl:ENSG00000146007|Vega:OTTHUMG00000129503 +153562 MARVELD2 MIM:610572|HGNC:HGNC:26401|Ensembl:ENSG00000152939|Vega:OTTHUMG00000162512 +153571 C5orf38 MIM:610522|HGNC:HGNC:24226|Ensembl:ENSG00000186493|Vega:OTTHUMG00000161741 +153572 IRX2 MIM:606198|HGNC:HGNC:14359|Ensembl:ENSG00000170561|Vega:OTTHUMG00000090377 +153579 BTNL9 HGNC:HGNC:24176|Ensembl:ENSG00000165810|Vega:OTTHUMG00000133152 +153642 ARSK MIM:610011|HGNC:HGNC:25239|Ensembl:ENSG00000164291|Vega:OTTHUMG00000121166 +153643 FAM81B HGNC:HGNC:26335|Ensembl:ENSG00000153347|Vega:OTTHUMG00000162837 +153657 TTC23L MIM:616344|HGNC:HGNC:26355|Ensembl:ENSG00000205838|Vega:OTTHUMG00000162020 +153684 LOC153684 Ensembl:ENSG00000215068 +153733 CCDC112 HGNC:HGNC:28599|Ensembl:ENSG00000164221|Vega:OTTHUMG00000128894 +153743 PPP1R2P3 HGNC:HGNC:16318|Ensembl:ENSG00000231989|Vega:OTTHUMG00000163467 +153745 FAM71B HGNC:HGNC:28397|Ensembl:ENSG00000170613|Vega:OTTHUMG00000130246 +153768 PRELID2 HGNC:HGNC:28306|Ensembl:ENSG00000186314|Vega:OTTHUMG00000163384 +153769 SH3RF2 MIM:613377|HGNC:HGNC:26299|Ensembl:ENSG00000156463|Vega:OTTHUMG00000129685 +153770 PLAC8L1 HGNC:HGNC:31746|Ensembl:ENSG00000173261|Vega:OTTHUMG00000163418 +153830 RNF145 HGNC:HGNC:20853|Ensembl:ENSG00000145860|Vega:OTTHUMG00000130306 +153842 SEM1P1 HGNC:HGNC:24454 +153893 LOC153893 - +153910 LOC153910 Ensembl:ENSG00000236366 +153918 ZC2HC1B HGNC:HGNC:21174|Ensembl:ENSG00000118491|Vega:OTTHUMG00000015734 +153932 SRP72P2 HGNC:HGNC:31096 +154007 SNRNP48 HGNC:HGNC:21368|Ensembl:ENSG00000168566|Vega:OTTHUMG00000014213 +154043 CNKSR3 MIM:617476|HGNC:HGNC:23034|Ensembl:ENSG00000153721|Vega:OTTHUMG00000015873 +154064 RAET1L MIM:611047|HGNC:HGNC:16798|Ensembl:ENSG00000155918|Vega:OTTHUMG00000015809 +154075 SAMD3 HGNC:HGNC:21574|Ensembl:ENSG00000164483|Vega:OTTHUMG00000015556 +154089 LINC01312 HGNC:HGNC:28525 +154091 SLC2A12 MIM:610372|HGNC:HGNC:18067|Ensembl:ENSG00000146411|Vega:OTTHUMG00000015611 +154092 LINC01010 HGNC:HGNC:48978 +154141 MBOAT1 MIM:611732|HGNC:HGNC:21579|Ensembl:ENSG00000172197|Vega:OTTHUMG00000014334 +154150 HDGFL1 HGNC:HGNC:21095|Ensembl:ENSG00000112273|Vega:OTTHUMG00000016206 +154197 PNLDC1 HGNC:HGNC:21185|Ensembl:ENSG00000146453|Vega:OTTHUMG00000015941 +154214 RNF217 HGNC:HGNC:21487|Ensembl:ENSG00000146373|Vega:OTTHUMG00000015504 +154215 NKAIN2 MIM:609758|HGNC:HGNC:16443|Ensembl:ENSG00000188580|Vega:OTTHUMG00000015500 +154288 KHDC3L MIM:611687|HGNC:HGNC:33699|Ensembl:ENSG00000203908|Vega:OTTHUMG00000015024 +154313 CFAP206 HGNC:HGNC:21405|Ensembl:ENSG00000213204|Ensembl:ENSG00000272514|Vega:OTTHUMG00000015173|Vega:OTTHUMG00000185391 +154386 LINC01600 HGNC:HGNC:21600|Ensembl:ENSG00000164385 +154442 BVES-AS1 HGNC:HGNC:21223|Ensembl:ENSG00000203808 +154449 LOC154449 Ensembl:ENSG00000230960 +154467 CCDC167 HGNC:HGNC:21239|Ensembl:ENSG00000198937|Vega:OTTHUMG00000014625 +154661 RUNDC3B MIM:617295|HGNC:HGNC:30286|Ensembl:ENSG00000105784|Vega:OTTHUMG00000131035 +154664 ABCA13 MIM:607807|HGNC:HGNC:14638|Ensembl:ENSG00000179869|Vega:OTTHUMG00000155840 +154743 BMT2 HGNC:HGNC:26475|Ensembl:ENSG00000164603|Vega:OTTHUMG00000155233 +154754 PRSS3P2 HGNC:HGNC:43788 +154761 LOC154761 Ensembl:ENSG00000253882 +154790 CLEC2L HGNC:HGNC:21969|Ensembl:ENSG00000236279|Vega:OTTHUMG00000164900 +154791 FMC1 HGNC:HGNC:26946|Ensembl:ENSG00000164898|Vega:OTTHUMG00000151719 +154796 AMOT MIM:300410|HGNC:HGNC:17810|Ensembl:ENSG00000126016|Vega:OTTHUMG00000022216 +154807 VKORC1L1 MIM:608838|HGNC:HGNC:21492|Ensembl:ENSG00000196715|Vega:OTTHUMG00000129449 +154810 AMOTL1 MIM:614657|HGNC:HGNC:17811|Ensembl:ENSG00000166025|Vega:OTTHUMG00000167828 +154822 LINC00689 HGNC:HGNC:27217|Ensembl:ENSG00000231419 +154860 FEZF1-AS1 HGNC:HGNC:41001|Ensembl:ENSG00000230316 +154865 IQUB HGNC:HGNC:21995|Ensembl:ENSG00000164675|Vega:OTTHUMG00000157347 +154872 C7orf77 HGNC:HGNC:51256|Ensembl:ENSG00000275356|Vega:OTTHUMG00000189249 +154881 KCTD7 MIM:611725|HGNC:HGNC:21957|Ensembl:ENSG00000243335|Vega:OTTHUMG00000129543 +154907 C7orf66 HGNC:HGNC:33712 +154937 LOC154937 - +155006 TMEM213 HGNC:HGNC:27220|Ensembl:ENSG00000214128|Vega:OTTHUMG00000157182 +155019 ST13P7 HGNC:HGNC:18558 +155038 GIMAP8 MIM:616962|HGNC:HGNC:21792|Ensembl:ENSG00000171115|Vega:OTTHUMG00000158327 +155051 CRYGN MIM:609603|HGNC:HGNC:20458|Ensembl:ENSG00000127377|Vega:OTTHUMG00000157353 +155054 ZNF425 HGNC:HGNC:20690|Ensembl:ENSG00000204947|Vega:OTTHUMG00000158971 +155060 LOC155060 Ensembl:ENSG00000244560 +155061 ZNF746 MIM:613914|HGNC:HGNC:21948|Ensembl:ENSG00000181220|Vega:OTTHUMG00000158972 +155066 ATP6V0E2 MIM:611019|HGNC:HGNC:21723|Ensembl:ENSG00000171130|Vega:OTTHUMG00000158094 +155100 CCT8L1P HGNC:HGNC:32153 +155184 SLC2A7 MIM:610371|HGNC:HGNC:13445|Ensembl:ENSG00000197241|Vega:OTTHUMG00000057499 +155185 AMZ1 MIM:615168|HGNC:HGNC:22231|Ensembl:ENSG00000174945|Vega:OTTHUMG00000152111 +155340 OR7E136P HGNC:HGNC:19557 +155368 METTL27 MIM:612546|HGNC:HGNC:19068|Ensembl:ENSG00000165171|Vega:OTTHUMG00000130033 +155370 SBDSP1 HGNC:HGNC:21646|Ensembl:ENSG00000225648 +155382 VPS37D MIM:610039|HGNC:HGNC:18287|Ensembl:ENSG00000176428|Vega:OTTHUMG00000157227 +155400 NSUN5P1 HGNC:HGNC:19146|Ensembl:ENSG00000223705 +155435 RBM33 HGNC:HGNC:27223|Ensembl:ENSG00000184863|Vega:OTTHUMG00000150260 +155465 AGR3 MIM:609482|HGNC:HGNC:24167|Ensembl:ENSG00000173467|Vega:OTTHUMG00000128411 +157206 RPL21P11 HGNC:HGNC:19800 +157247 MGC27345 - +157273 LOC157273 Ensembl:ENSG00000254235 +157285 PRAG1 MIM:617344|HGNC:HGNC:25438|Ensembl:ENSG00000275342|Vega:OTTHUMG00000163709 +157310 PEBP4 MIM:612473|HGNC:HGNC:28319|Ensembl:ENSG00000134020|Vega:OTTHUMG00000163749 +157313 CDCA2 HGNC:HGNC:14623|Ensembl:ENSG00000184661|Vega:OTTHUMG00000099429 +157317 CYCSP55 HGNC:HGNC:21252 +157376 FER1L6-AS2 HGNC:HGNC:26534|Ensembl:ENSG00000253868 +157378 TMEM65 MIM:616609|HGNC:HGNC:25203|Ensembl:ENSG00000164983|Vega:OTTHUMG00000165021 +157381 LINC00964 HGNC:HGNC:27226|Ensembl:ENSG00000249816 +157489 SDAD1P1 HGNC:HGNC:31403 +157506 RDH10 MIM:607599|HGNC:HGNC:19975|Ensembl:ENSG00000121039|Vega:OTTHUMG00000164492 +157530 ST13P6 HGNC:HGNC:18557 +157556 BAALC-AS2 HGNC:HGNC:28595|Ensembl:ENSG00000236939 +157567 ANKRD46 HGNC:HGNC:27229|Ensembl:ENSG00000186106|Vega:OTTHUMG00000164724 +157570 ESCO2 MIM:609353|HGNC:HGNC:27230|Ensembl:ENSG00000171320|Vega:OTTHUMG00000163901 +157574 FBXO16 MIM:608519|HGNC:HGNC:13618|Ensembl:ENSG00000214050|Vega:OTTHUMG00000102147 +157627 LINC00599 HGNC:HGNC:27231|Ensembl:ENSG00000253230 +157638 FAM84B MIM:609483|HGNC:HGNC:24166|Ensembl:ENSG00000168672|Vega:OTTHUMG00000165034 +157657 C8orf37 MIM:614477|HGNC:HGNC:27232|Ensembl:ENSG00000156172|Vega:OTTHUMG00000164663 +157667 MYL12AP1 HGNC:HGNC:51648 +157680 VPS13B MIM:607817|HGNC:HGNC:2183|Ensembl:ENSG00000132549|Vega:OTTHUMG00000140383 +157693 FAM87A HGNC:HGNC:27233|Ensembl:ENSG00000182366 +157695 TDRP HGNC:HGNC:26951|Ensembl:ENSG00000180190|Vega:OTTHUMG00000163593 +157697 ERICH1 HGNC:HGNC:27234|Ensembl:ENSG00000104714|Vega:OTTHUMG00000129163 +157708 SEC11B HGNC:HGNC:31884 +157713 LYPLA1P3 HGNC:HGNC:44007 +157724 SLC7A13 MIM:617256|HGNC:HGNC:23092|Ensembl:ENSG00000164893|Vega:OTTHUMG00000163663 +157739 TDH MIM:615174|HGNC:HGNC:15547|Ensembl:ENSG00000154316 +157753 TMEM74 MIM:613935|HGNC:HGNC:26409|Ensembl:ENSG00000164841|Vega:OTTHUMG00000164881 +157769 FAM91A1 HGNC:HGNC:26306|Ensembl:ENSG00000176853|Vega:OTTHUMG00000133021 +157773 C8orf48 HGNC:HGNC:26345|Ensembl:ENSG00000164743|Vega:OTTHUMG00000165482 +157777 MCMDC2 MIM:617545|HGNC:HGNC:26368|Ensembl:ENSG00000178460|Vega:OTTHUMG00000157068 +157807 CLVS1 MIM:611292|HGNC:HGNC:23139|Ensembl:ENSG00000177182|Vega:OTTHUMG00000164334 +157848 NKX6-3 MIM:610772|HGNC:HGNC:26328|Ensembl:ENSG00000165066|Vega:OTTHUMG00000164083 +157855 KCNU1 MIM:615215|HGNC:HGNC:18867|Ensembl:ENSG00000215262|Vega:OTTHUMG00000163981 +157869 SBSPON HGNC:HGNC:30362|Ensembl:ENSG00000164764|Vega:OTTHUMG00000157144 +157916 IL6RP1 HGNC:HGNC:6020 +157922 CAMSAP1 MIM:613774|HGNC:HGNC:19946|Ensembl:ENSG00000130559|Vega:OTTHUMG00000020918 +157927 C9orf62 HGNC:HGNC:28581 +157956 CDC20P1 HGNC:HGNC:29487 +157983 C9orf66 HGNC:HGNC:26436|Ensembl:ENSG00000183784|Vega:OTTHUMG00000021017 +158011 IFNA12P HGNC:HGNC:5443 +158035 LINC00032 HGNC:HGNC:16506|Ensembl:ENSG00000283945 +158038 LINGO2 MIM:609793|HGNC:HGNC:21207|Ensembl:ENSG00000174482|Vega:OTTHUMG00000019721 +158046 NXNL2 MIM:615299|HGNC:HGNC:30482|Ensembl:ENSG00000130045|Vega:OTTHUMG00000020170 +158055 C9orf163 HGNC:HGNC:26718 +158056 MAMDC4 MIM:617208|HGNC:HGNC:24083|Ensembl:ENSG00000177943|Vega:OTTHUMG00000020951 +158062 LCN6 MIM:609379|HGNC:HGNC:17337|Ensembl:ENSG00000204003|Ensembl:ENSG00000267206|Vega:OTTHUMG00000020941|Vega:OTTHUMG00000180116 +158067 AK8 MIM:615365|HGNC:HGNC:26526|Ensembl:ENSG00000165695|Vega:OTTHUMG00000021009 +158078 EEF1A1P5 HGNC:HGNC:3200 +158104 RPS10P3 HGNC:HGNC:23684 +158131 OR1Q1 HGNC:HGNC:8223|Ensembl:ENSG00000165202|Vega:OTTHUMG00000020615 +158135 TTLL11 HGNC:HGNC:18113|Ensembl:ENSG00000175764|Vega:OTTHUMG00000020597 +158158 RASEF MIM:611344|HGNC:HGNC:26464|Ensembl:ENSG00000165105|Vega:OTTHUMG00000020100 +158160 HSD17B7P2 HGNC:HGNC:28120|Ensembl:ENSG00000099251 +158172 SERPINH1P1 HGNC:HGNC:19917 +158219 TTC39B MIM:613574|HGNC:HGNC:23704|Ensembl:ENSG00000155158|Vega:OTTHUMG00000019581 +158222 LDHAP4 HGNC:HGNC:6539 +158228 FAM201A HGNC:HGNC:27239 +158234 TRMT10B HGNC:HGNC:26454|Ensembl:ENSG00000165275|Vega:OTTHUMG00000019933 +158248 TTC16 HGNC:HGNC:26536|Ensembl:ENSG00000167094|Vega:OTTHUMG00000020711 +158257 MIRLET7DHG HGNC:HGNC:37186|Ensembl:ENSG00000230262 +158293 FAM120AOS HGNC:HGNC:23389|Ensembl:ENSG00000188938|Vega:OTTHUMG00000020251 +158297 SAXO1 MIM:616292|HGNC:HGNC:28566|Ensembl:ENSG00000155875|Vega:OTTHUMG00000019609 +158314 LINC00475 HGNC:HGNC:23569 +158326 FREM1 MIM:608944|HGNC:HGNC:23399|Ensembl:ENSG00000164946|Vega:OTTHUMG00000019575 +158345 RPL4P5 HGNC:HGNC:35699 +158358 KIAA2026 HGNC:HGNC:23378|Ensembl:ENSG00000183354|Vega:OTTHUMG00000019507 +158373 YBX1P10 HGNC:HGNC:42432 +158376 SPAAR HGNC:HGNC:27244|Ensembl:ENSG00000235387|Vega:OTTHUMG00000019887 +158381 ATP8B5P HGNC:HGNC:27245|Ensembl:ENSG00000179766 +158383 YWHAZP6 HGNC:HGNC:30849 +158399 ZNF483 HGNC:HGNC:23384|Ensembl:ENSG00000173258|Vega:OTTHUMG00000020490 +158401 C9orf84 HGNC:HGNC:26535|Ensembl:ENSG00000165181|Vega:OTTHUMG00000020495 +158405 KIAA1958 MIM:617390|HGNC:HGNC:23427|Ensembl:ENSG00000165185|Vega:OTTHUMG00000020508 +158427 TSTD2 HGNC:HGNC:30087|Ensembl:ENSG00000136925|Vega:OTTHUMG00000020328 +158431 ZNF782 HGNC:HGNC:33110|Ensembl:ENSG00000196597|Vega:OTTHUMG00000020310 +158434 LOC158434 Ensembl:ENSG00000275465 +158435 LOC158435 - +158441 PSMA7P HGNC:HGNC:20631 +158452 ASS1P3 HGNC:HGNC:766 +158471 PRUNE2 MIM:610691|HGNC:HGNC:25209|Ensembl:ENSG00000106772|Vega:OTTHUMG00000020047 +158506 ZNF645 HGNC:HGNC:26371|Ensembl:ENSG00000175809|Vega:OTTHUMG00000021242 +158511 CSAG1 MIM:300944|HGNC:HGNC:24294|Ensembl:ENSG00000198930|Vega:OTTHUMG00000022648 +158521 FMR1NB HGNC:HGNC:26372|Ensembl:ENSG00000176988|Vega:OTTHUMG00000022608 +158572 USP27X-AS1 HGNC:HGNC:27249|Ensembl:ENSG00000234390 +158584 FAAH2 MIM:300654|HGNC:HGNC:26440|Ensembl:ENSG00000165591|Vega:OTTHUMG00000021684 +158586 ZXDB MIM:300236|HGNC:HGNC:13199|Ensembl:ENSG00000198455|Vega:OTTHUMG00000021685 +158674 RPSAP3 HGNC:HGNC:19792 +158696 LINC00889 HGNC:HGNC:26410 +158724 FAM47A HGNC:HGNC:29962|Ensembl:ENSG00000185448|Vega:OTTHUMG00000021339 +158747 MOSPD2 HGNC:HGNC:28381|Ensembl:ENSG00000130150|Vega:OTTHUMG00000021170 +158763 ARHGAP36 MIM:300937|HGNC:HGNC:26388|Ensembl:ENSG00000147256|Vega:OTTHUMG00000022402 +158781 LOC158781 - +158787 RIBC1 HGNC:HGNC:26537|Ensembl:ENSG00000158423|Vega:OTTHUMG00000021615 +158798 AKAP14 MIM:300462|HGNC:HGNC:24061|Ensembl:ENSG00000186471|Vega:OTTHUMG00000022285 +158800 RHOXF1 MIM:300446|HGNC:HGNC:29993|Ensembl:ENSG00000101883|Vega:OTTHUMG00000022290 +158801 NKAPP1 HGNC:HGNC:26706|Ensembl:ENSG00000233382 +158809 MAGEB6 MIM:300467|HGNC:HGNC:23796|Ensembl:ENSG00000176746|Vega:OTTHUMG00000021285 +158830 CXorf65 HGNC:HGNC:33713|Ensembl:ENSG00000204165|Vega:OTTHUMG00000021785 +158833 AWAT1 MIM:300924|HGNC:HGNC:23252|Ensembl:ENSG00000204195|Vega:OTTHUMG00000021773 +158835 AWAT2 MIM:300925|HGNC:HGNC:23251|Ensembl:ENSG00000147160|Vega:OTTHUMG00000021763 +158866 ZDHHC15 MIM:300576|HGNC:HGNC:20342|Ensembl:ENSG00000102383|Vega:OTTHUMG00000021866 +158880 USP51 HGNC:HGNC:23086|Ensembl:ENSG00000247746|Vega:OTTHUMG00000021656 +158905 PHF10P1 HGNC:HGNC:23210 +158931 TCEAL6 HGNC:HGNC:24553|Ensembl:ENSG00000204071|Vega:OTTHUMG00000022050 +158948 LOC158948 - +158960 CH17-340M24.3 Ensembl:ENSG00000197180 +158983 H2BFWT MIM:300507|HGNC:HGNC:27252|Ensembl:ENSG00000123569|Vega:OTTHUMG00000022120 +159007 LOC159007 - +159013 CXorf38 HGNC:HGNC:28589|Ensembl:ENSG00000185753|Vega:OTTHUMG00000024104 +159090 FAM122B HGNC:HGNC:30490|Ensembl:ENSG00000156504|Vega:OTTHUMG00000022461 +159091 FAM122C HGNC:HGNC:25202|Ensembl:ENSG00000156500|Vega:OTTHUMG00000022716 +159119 HSFY2 HGNC:HGNC:23950|Ensembl:ENSG00000169953|Vega:OTTHUMG00000041947 +159125 RBMY2EP HGNC:HGNC:23890|Ensembl:ENSG00000223637 +159162 RBMY2FP HGNC:HGNC:23891|Ensembl:ENSG00000243040 +159163 RBMY1F HGNC:HGNC:23974|Ensembl:ENSG00000169800|Vega:OTTHUMG00000043593 +159195 USP54 HGNC:HGNC:23513|Ensembl:ENSG00000166348|Vega:OTTHUMG00000018469 +159296 NKX2-3 MIM:606727|HGNC:HGNC:7836|Ensembl:ENSG00000119919|Vega:OTTHUMG00000018887 +159371 SLC35G1 MIM:617167|HGNC:HGNC:26607|Ensembl:ENSG00000176273|Vega:OTTHUMG00000018779 +159686 CFAP58 HGNC:HGNC:26676|Ensembl:ENSG00000120051|Vega:OTTHUMG00000019007 +159770 CBX3P1 HGNC:HGNC:33950 +159963 SLC5A12 MIM:612455|HGNC:HGNC:28750|Ensembl:ENSG00000148942|Vega:OTTHUMG00000150706 +159989 DEUP1 MIM:617148|HGNC:HGNC:26344|Ensembl:ENSG00000165325|Vega:OTTHUMG00000167441 +160065 PATE1 MIM:606861|HGNC:HGNC:24664|Ensembl:ENSG00000171053|Vega:OTTHUMG00000165855 +160140 C11orf65 HGNC:HGNC:28519|Ensembl:ENSG00000166323|Vega:OTTHUMG00000166489 +160287 LDHAL6A HGNC:HGNC:28335|Ensembl:ENSG00000166800|Vega:OTTHUMG00000167724 +160298 C11orf42 HGNC:HGNC:28541|Ensembl:ENSG00000180878|Vega:OTTHUMG00000133377 +160313 KRT19P2 HGNC:HGNC:33423|Ensembl:ENSG00000216306 +160335 TMTC2 MIM:615856|HGNC:HGNC:25440|Ensembl:ENSG00000179104|Vega:OTTHUMG00000169736 +160364 CLEC12A MIM:612088|HGNC:HGNC:31713|Ensembl:ENSG00000172322|Vega:OTTHUMG00000168396 +160365 CLECL1 MIM:607467|HGNC:HGNC:24462|Ensembl:ENSG00000184293|Vega:OTTHUMG00000168459 +160410 PSMC6P2 HGNC:HGNC:30149 +160418 TMTC3 MIM:617218|HGNC:HGNC:26899|Ensembl:ENSG00000139324|Vega:OTTHUMG00000169887 +160419 C12orf50 HGNC:HGNC:26665|Ensembl:ENSG00000165805|Vega:OTTHUMG00000169869 +160428 ALDH1L2 MIM:613584|HGNC:HGNC:26777|Ensembl:ENSG00000136010|Vega:OTTHUMG00000169823 +160492 LMNTD1 MIM:617254|HGNC:HGNC:26683|Ensembl:ENSG00000152936|Vega:OTTHUMG00000169052 +160518 DENND5B MIM:617279|HGNC:HGNC:28338|Ensembl:ENSG00000170456|Vega:OTTHUMG00000169034 +160622 GRASP MIM:612027|HGNC:HGNC:18707|Ensembl:ENSG00000161835|Vega:OTTHUMG00000169595 +160728 SLC5A8 MIM:608044|HGNC:HGNC:19119|Ensembl:ENSG00000256870|Vega:OTTHUMG00000170499 +160760 PPTC7 MIM:609668|HGNC:HGNC:30695|Ensembl:ENSG00000196850|Vega:OTTHUMG00000169529 +160762 CCDC63 HGNC:HGNC:26669|Ensembl:ENSG00000173093|Vega:OTTHUMG00000169534 +160777 CCDC60 HGNC:HGNC:28610|Ensembl:ENSG00000183273|Vega:OTTHUMG00000168943 +160824 SP3P HGNC:HGNC:35430 +160851 DGKH MIM:604071|HGNC:HGNC:2854|Ensembl:ENSG00000102780|Vega:OTTHUMG00000016804 +160857 CCDC122 MIM:613408|HGNC:HGNC:26478|Ensembl:ENSG00000151773|Vega:OTTHUMG00000017413 +160897 GPR180 MIM:607787|HGNC:HGNC:28899|Ensembl:ENSG00000152749|Vega:OTTHUMG00000017207 +161003 STOML3 MIM:608327|HGNC:HGNC:19420|Ensembl:ENSG00000133115|Vega:OTTHUMG00000016763 +161142 FAM71D HGNC:HGNC:20101|Ensembl:ENSG00000172717|Vega:OTTHUMG00000142819 +161145 TMEM229B HGNC:HGNC:20130|Ensembl:ENSG00000198133|Vega:OTTHUMG00000171270 +161159 ACTN1-AS1 HGNC:HGNC:20131|Ensembl:ENSG00000259062 +161176 SYNE3 MIM:610861|HGNC:HGNC:19861|Ensembl:ENSG00000176438|Vega:OTTHUMG00000171632 +161198 CLEC14A MIM:616845|HGNC:HGNC:19832|Ensembl:ENSG00000176435|Vega:OTTHUMG00000140248 +161247 FITM1 MIM:612028|HGNC:HGNC:33714|Ensembl:ENSG00000139914|Vega:OTTHUMG00000133476 +161253 REM2 MIM:616955|HGNC:HGNC:20248|Ensembl:ENSG00000139890|Vega:OTTHUMG00000170277 +161271 OR4H12P HGNC:HGNC:19433 +161291 TMEM30B MIM:611029|HGNC:HGNC:27254|Ensembl:ENSG00000182107|Vega:OTTHUMG00000171426 +161342 LINC00519 HGNC:HGNC:19838 +161357 MDGA2 MIM:611128|HGNC:HGNC:19835|Ensembl:ENSG00000139915|Vega:OTTHUMG00000029429 +161394 SAMD15 HGNC:HGNC:18631|Ensembl:ENSG00000100583|Vega:OTTHUMG00000167428 +161406 RPL7AP10 HGNC:HGNC:32433 +161424 NOP9 HGNC:HGNC:19826|Ensembl:ENSG00000196943|Vega:OTTHUMG00000029342 +161436 EML5 HGNC:HGNC:18197|Ensembl:ENSG00000165521|Vega:OTTHUMG00000170811 +161497 STRC MIM:606440|HGNC:HGNC:16035|Ensembl:ENSG00000242866|Vega:OTTHUMG00000059899 +161502 CFAP161 HGNC:HGNC:26782|Ensembl:ENSG00000156206|Vega:OTTHUMG00000172263 +161514 TBC1D21 HGNC:HGNC:28536|Ensembl:ENSG00000167139|Vega:OTTHUMG00000137594 +161582 DNAAF4 MIM:608706|HGNC:HGNC:21493|Ensembl:ENSG00000256061|Vega:OTTHUMG00000132008 +161635 CSNK1A1P1 HGNC:HGNC:30446 +161725 OTUD7A MIM:612024|HGNC:HGNC:20718|Ensembl:ENSG00000169918|Vega:OTTHUMG00000129275 +161742 SPRED1 MIM:609291|HGNC:HGNC:20249|Ensembl:ENSG00000166068|Vega:OTTHUMG00000172377 +161753 ODF3L1 HGNC:HGNC:28735|Ensembl:ENSG00000182950|Vega:OTTHUMG00000142837 +161779 PGBD4 HGNC:HGNC:19401|Ensembl:ENSG00000182405|Vega:OTTHUMG00000129370 +161823 ADAL HGNC:HGNC:31853|Ensembl:ENSG00000168803|Vega:OTTHUMG00000176646 +161829 EXD1 HGNC:HGNC:28507|Ensembl:ENSG00000178997|Vega:OTTHUMG00000130232 +161835 FSIP1 MIM:615795|HGNC:HGNC:21674|Ensembl:ENSG00000150667|Vega:OTTHUMG00000172456 +161882 ZFPM1 MIM:601950|HGNC:HGNC:19762|Ensembl:ENSG00000179588|Vega:OTTHUMG00000173152 +161931 ADAD2 HGNC:HGNC:30714|Ensembl:ENSG00000140955|Vega:OTTHUMG00000137637 +162073 ITPRIPL2 HGNC:HGNC:27257|Ensembl:ENSG00000205730|Vega:OTTHUMG00000177199 +162083 C16orf82 HGNC:HGNC:30755|Ensembl:ENSG00000234186 +162137 LOC162137 - +162239 ZFP1 MIM:617230|HGNC:HGNC:23328|Ensembl:ENSG00000184517|Vega:OTTHUMG00000137602 +162282 ANKFN1 HGNC:HGNC:26766|Ensembl:ENSG00000153930|Vega:OTTHUMG00000155010 +162333 MARCH10 MIM:613337|HGNC:HGNC:26655|Ensembl:ENSG00000173838|Vega:OTTHUMG00000179192 +162387 MFSD6L HGNC:HGNC:26656|Ensembl:ENSG00000185156|Vega:OTTHUMG00000178584 +162394 SLFN5 MIM:614952|HGNC:HGNC:28286|Ensembl:ENSG00000166750|Vega:OTTHUMG00000179858 +162417 NAGS MIM:608300|HGNC:HGNC:17996|Ensembl:ENSG00000161653|Vega:OTTHUMG00000181802 +162427 RETREG3 MIM:616498|HGNC:HGNC:27258|Ensembl:ENSG00000141699|Vega:OTTHUMG00000180275 +162461 TMEM92 HGNC:HGNC:26579|Ensembl:ENSG00000167105|Vega:OTTHUMG00000162060 +162466 PHOSPHO1 HGNC:HGNC:16815|Ensembl:ENSG00000173868|Vega:OTTHUMG00000161305 +162494 RHBDL3 HGNC:HGNC:16502|Ensembl:ENSG00000141314|Vega:OTTHUMG00000179568 +162514 TRPV3 MIM:607066|HGNC:HGNC:18084|Ensembl:ENSG00000167723|Vega:OTTHUMG00000090695 +162515 SLC16A11 MIM:615765|HGNC:HGNC:23093|Ensembl:ENSG00000174326|Vega:OTTHUMG00000102087 +162517 FBXO39 MIM:609106|HGNC:HGNC:28565|Ensembl:ENSG00000177294|Vega:OTTHUMG00000102062 +162540 SPPL2C MIM:608284|HGNC:HGNC:28902|Ensembl:ENSG00000185294|Vega:OTTHUMG00000178247 +162605 KRT28 MIM:616677|HGNC:HGNC:30842|Ensembl:ENSG00000173908|Vega:OTTHUMG00000133365 +162632 USP32P1 HGNC:HGNC:43570|Ensembl:ENSG00000188933 +162655 ZNF519 HGNC:HGNC:30574|Ensembl:ENSG00000175322|Vega:OTTHUMG00000182055 +162681 C18orf54 MIM:613258|HGNC:HGNC:13796|Ensembl:ENSG00000166845|Vega:OTTHUMG00000132703 +162699 TCEB3C HGNC:HGNC:24617|Ensembl:ENSG00000183791|Vega:OTTHUMG00000132651 +162962 ZNF836 HGNC:HGNC:34333|Ensembl:ENSG00000196267|Vega:OTTHUMG00000182567 +162963 ZNF610 HGNC:HGNC:26687|Ensembl:ENSG00000167554|Vega:OTTHUMG00000182645 +162966 ZNF600 HGNC:HGNC:30951|Ensembl:ENSG00000189190|Vega:OTTHUMG00000182686 +162967 ZNF320 MIM:606427|HGNC:HGNC:13842|Ensembl:ENSG00000182986|Ensembl:ENSG00000283088|Vega:OTTHUMG00000182797|Vega:OTTHUMG00000191567 +162968 ZNF497 HGNC:HGNC:23714|Ensembl:ENSG00000174586|Vega:OTTHUMG00000183510 +162972 ZNF550 HGNC:HGNC:28643|Ensembl:ENSG00000251369|Vega:OTTHUMG00000133709 +162979 ZNF296 MIM:613226|HGNC:HGNC:15981|Ensembl:ENSG00000170684|Vega:OTTHUMG00000181766 +162989 DEDD2 MIM:617078|HGNC:HGNC:24450|Ensembl:ENSG00000160570|Vega:OTTHUMG00000182763 +162993 ZNF846 HGNC:HGNC:27260|Ensembl:ENSG00000196605|Vega:OTTHUMG00000180208 +162998 OR7D2 HGNC:HGNC:8378|Ensembl:ENSG00000188000|Vega:OTTHUMG00000179934 +163007 CYP2T3P HGNC:HGNC:18853 +163033 ZNF579 HGNC:HGNC:26646|Ensembl:ENSG00000218891|Vega:OTTHUMG00000180857 +163049 ZNF791 HGNC:HGNC:26895|Ensembl:ENSG00000173875|Vega:OTTHUMG00000156426 +163050 ZNF564 HGNC:HGNC:31106|Ensembl:ENSG00000249709|Vega:OTTHUMG00000156418 +163051 ZNF709 HGNC:HGNC:20629|Ensembl:ENSG00000196826|Ensembl:ENSG00000242852|Vega:OTTHUMG00000156406|Vega:OTTHUMG00000162246 +163059 ZNF433 HGNC:HGNC:20811|Ensembl:ENSG00000197647|Vega:OTTHUMG00000156427 +163071 ZNF114 MIM:603996|HGNC:HGNC:12894|Ensembl:ENSG00000178150|Vega:OTTHUMG00000183191 +163081 ZNF567 HGNC:HGNC:28696|Ensembl:ENSG00000189042|Vega:OTTHUMG00000180898 +163087 ZNF383 HGNC:HGNC:18609|Ensembl:ENSG00000188283|Vega:OTTHUMG00000181890 +163088 TAF9P3 HGNC:HGNC:30678 +163115 ZNF781 HGNC:HGNC:26745|Ensembl:ENSG00000196381|Vega:OTTHUMG00000182106 +163126 EID2 MIM:609773|HGNC:HGNC:28292|Ensembl:ENSG00000176396|Vega:OTTHUMG00000074073 +163131 ZNF780B HGNC:HGNC:33109|Ensembl:ENSG00000128000|Vega:OTTHUMG00000155118 +163154 PRR22 HGNC:HGNC:28354|Ensembl:ENSG00000212123|Vega:OTTHUMG00000180553 +163175 LGI4 MIM:608303|HGNC:HGNC:18712|Ensembl:ENSG00000153902|Vega:OTTHUMG00000044558 +163183 SYNE4 MIM:615535|HGNC:HGNC:26703|Ensembl:ENSG00000181392|Vega:OTTHUMG00000048135 +163223 ZNF676 HGNC:HGNC:20429|Ensembl:ENSG00000196109|Vega:OTTHUMG00000182934 +163227 ZNF100 MIM:603982|HGNC:HGNC:12880|Ensembl:ENSG00000197020|Vega:OTTHUMG00000182872 +163255 ZNF540 MIM:613903|HGNC:HGNC:25331|Ensembl:ENSG00000171817|Vega:OTTHUMG00000182053 +163259 DENND2C HGNC:HGNC:24748|Ensembl:ENSG00000175984|Vega:OTTHUMG00000011893 +163351 GBP6 MIM:612467|HGNC:HGNC:25395|Ensembl:ENSG00000183347|Vega:OTTHUMG00000010123 +163404 PLPPR5 MIM:617287|HGNC:HGNC:31703|Ensembl:ENSG00000117598|Vega:OTTHUMG00000010738 +163479 FNDC7 HGNC:HGNC:26668|Ensembl:ENSG00000143107|Vega:OTTHUMG00000011120 +163486 DENND1B MIM:613292|HGNC:HGNC:28404|Ensembl:ENSG00000213047|Vega:OTTHUMG00000035653 +163589 TDRD5 HGNC:HGNC:20614|Ensembl:ENSG00000162782|Vega:OTTHUMG00000035259 +163590 TOR1AIP2 MIM:614513|HGNC:HGNC:24055|Ensembl:ENSG00000169905|Vega:OTTHUMG00000035265 +163688 CALML6 MIM:610171|HGNC:HGNC:24193|Ensembl:ENSG00000169885|Vega:OTTHUMG00000000943 +163702 IFNLR1 MIM:607404|HGNC:HGNC:18584|Ensembl:ENSG00000185436|Vega:OTTHUMG00000003036 +163720 CYP4Z2P HGNC:HGNC:24426|Ensembl:ENSG00000154198 +163732 CITED4 MIM:606815|HGNC:HGNC:18696|Ensembl:ENSG00000179862|Vega:OTTHUMG00000007728 +163742 SLC25A3P1 HGNC:HGNC:26869|Ensembl:ENSG00000236253 +163747 LEXM MIM:616446|HGNC:HGNC:26854|Ensembl:ENSG00000162398|Vega:OTTHUMG00000009986 +163778 SPRR4 MIM:616363|HGNC:HGNC:23173|Ensembl:ENSG00000184148|Vega:OTTHUMG00000012450 +163782 KANK4 MIM:614612|HGNC:HGNC:27263|Ensembl:ENSG00000132854|Vega:OTTHUMG00000008971 +163786 SASS6 MIM:609321|HGNC:HGNC:25403|Ensembl:ENSG00000156876|Vega:OTTHUMG00000010754 +163859 SDE2 HGNC:HGNC:26643|Ensembl:ENSG00000143751|Vega:OTTHUMG00000037504 +163882 CNST MIM:613439|HGNC:HGNC:26486|Ensembl:ENSG00000162852|Vega:OTTHUMG00000040090 +163933 FAM43B HGNC:HGNC:31791|Ensembl:ENSG00000183114|Vega:OTTHUMG00000057491 +164045 HFM1 MIM:615684|HGNC:HGNC:20193|Ensembl:ENSG00000162669|Vega:OTTHUMG00000010093 +164091 PAQR7 MIM:607779|HGNC:HGNC:23146|Ensembl:ENSG00000182749|Vega:OTTHUMG00000007373 +164118 TTC24 HGNC:HGNC:32348|Ensembl:ENSG00000187862|Vega:OTTHUMG00000033202 +164127 CCDC185 HGNC:HGNC:26654|Ensembl:ENSG00000178395|Vega:OTTHUMG00000037987 +164153 UBL4B MIM:611127|HGNC:HGNC:32309|Ensembl:ENSG00000186150|Vega:OTTHUMG00000166989 +164237 WFDC13 HGNC:HGNC:16131|Ensembl:ENSG00000168634|Vega:OTTHUMG00000046333 +164284 APCDD1L HGNC:HGNC:26892|Ensembl:ENSG00000198768|Vega:OTTHUMG00000032845 +164312 LRRN4 HGNC:HGNC:16208|Ensembl:ENSG00000125872|Vega:OTTHUMG00000031825 +164380 CST13P HGNC:HGNC:44335|Ensembl:ENSG00000204663 +164395 TTLL9 HGNC:HGNC:16118|Ensembl:ENSG00000131044|Vega:OTTHUMG00000186843 +164592 CCDC116 HGNC:HGNC:26688|Ensembl:ENSG00000161180|Vega:OTTHUMG00000150821 +164633 CABP7 HGNC:HGNC:20834|Ensembl:ENSG00000100314|Vega:OTTHUMG00000151282 +164656 TMPRSS6 MIM:609862|HGNC:HGNC:16517|Ensembl:ENSG00000187045|Vega:OTTHUMG00000150541 +164668 APOBEC3H MIM:610976|HGNC:HGNC:24100|Ensembl:ENSG00000100298|Vega:OTTHUMG00000151082 +164684 WBP2NL MIM:610981|HGNC:HGNC:28389|Ensembl:ENSG00000183066|Vega:OTTHUMG00000151270 +164714 TTLL8 HGNC:HGNC:34000|Ensembl:ENSG00000138892|Vega:OTTHUMG00000150241 +164781 DAW1 HGNC:HGNC:26383|Ensembl:ENSG00000123977|Vega:OTTHUMG00000133190 +164832 LONRF2 HGNC:HGNC:24788|Ensembl:ENSG00000170500|Vega:OTTHUMG00000130668 +164837 CYCSP7 HGNC:HGNC:24422 +165055 CCDC138 HGNC:HGNC:26531|Ensembl:ENSG00000163006|Vega:OTTHUMG00000130980 +165082 ADGRF3 HGNC:HGNC:18989|Ensembl:ENSG00000173567|Vega:OTTHUMG00000150225 +165100 TEX44 HGNC:HGNC:28563|Ensembl:ENSG00000177673|Vega:OTTHUMG00000133226 +165140 OXER1 HGNC:HGNC:24884|Ensembl:ENSG00000162881|Vega:OTTHUMG00000128643 +165186 TOGARAM2 HGNC:HGNC:33715|Ensembl:ENSG00000189350|Vega:OTTHUMG00000128432 +165215 FAM171B HGNC:HGNC:29412|Ensembl:ENSG00000144369|Vega:OTTHUMG00000154278 +165257 C1QL2 MIM:614330|HGNC:HGNC:24181|Ensembl:ENSG00000144119|Vega:OTTHUMG00000153271 +165324 UBXN2A HGNC:HGNC:27265|Ensembl:ENSG00000173960|Vega:OTTHUMG00000125497 +165530 CLEC4F HGNC:HGNC:25357|Ensembl:ENSG00000152672|Vega:OTTHUMG00000129713 +165545 DQX1 HGNC:HGNC:20410|Ensembl:ENSG00000144045|Vega:OTTHUMG00000129965 +165631 PARP15 MIM:612066|HGNC:HGNC:26876|Ensembl:ENSG00000173200|Vega:OTTHUMG00000159523 +165679 SPTSSB MIM:610412|HGNC:HGNC:24045|Ensembl:ENSG00000196542|Vega:OTTHUMG00000159073 +165721 DNAJB8 MIM:611337|HGNC:HGNC:23699|Ensembl:ENSG00000179407|Vega:OTTHUMG00000159690 +165829 GPR156 MIM:610464|HGNC:HGNC:20844|Ensembl:ENSG00000175697|Vega:OTTHUMG00000159406 +165904 XIRP1 MIM:609777|HGNC:HGNC:14301|Ensembl:ENSG00000168334|Vega:OTTHUMG00000131297 +165918 RNF168 MIM:612688|HGNC:HGNC:26661|Ensembl:ENSG00000163961|Vega:OTTHUMG00000155582 +166012 CHST13 MIM:610124|HGNC:HGNC:21755|Ensembl:ENSG00000180767|Vega:OTTHUMG00000162721 +166336 PRICKLE2 MIM:608501|HGNC:HGNC:20340|Ensembl:ENSG00000163637|Vega:OTTHUMG00000158789 +166348 KBTBD12 HGNC:HGNC:25731|Ensembl:ENSG00000187715|Vega:OTTHUMG00000150508 +166378 SPATA5 MIM:613940|HGNC:HGNC:18119|Ensembl:ENSG00000145375|Vega:OTTHUMG00000133074 +166379 BBS12 MIM:610683|HGNC:HGNC:26648|Ensembl:ENSG00000181004|Vega:OTTHUMG00000133070 +166614 DCLK2 MIM:613166|HGNC:HGNC:19002|Ensembl:ENSG00000170390|Vega:OTTHUMG00000161444 +166647 ADGRA3 MIM:612303|HGNC:HGNC:13839|Ensembl:ENSG00000152990|Vega:OTTHUMG00000160926 +166655 TRIM60 HGNC:HGNC:21162|Ensembl:ENSG00000176979|Vega:OTTHUMG00000161262 +166752 FREM3 MIM:608946|HGNC:HGNC:25172|Ensembl:ENSG00000183090|Vega:OTTHUMG00000161577 +166785 MMAA MIM:607481|HGNC:HGNC:18871|Ensembl:ENSG00000151611|Vega:OTTHUMG00000161369 +166793 ZBTB49 MIM:616238|HGNC:HGNC:19883|Ensembl:ENSG00000168826|Vega:OTTHUMG00000090325 +166815 TIGD2 MIM:612973|HGNC:HGNC:18333|Ensembl:ENSG00000180346|Vega:OTTHUMG00000130946 +166824 RASSF6 MIM:612620|HGNC:HGNC:20796|Ensembl:ENSG00000169435|Vega:OTTHUMG00000130007 +166863 RBM46 HGNC:HGNC:28401|Ensembl:ENSG00000151962|Vega:OTTHUMG00000161543 +166929 SGMS2 MIM:611574|HGNC:HGNC:28395|Ensembl:ENSG00000164023|Vega:OTTHUMG00000131811 +166968 MIER3 HGNC:HGNC:26678|Ensembl:ENSG00000155545|Vega:OTTHUMG00000059589 +166979 CDC20B HGNC:HGNC:24222|Ensembl:ENSG00000164287|Vega:OTTHUMG00000131185 +167127 UGT3A2 MIM:616384|HGNC:HGNC:27266|Ensembl:ENSG00000168671|Vega:OTTHUMG00000131108 +167153 PAPD4 MIM:614121|HGNC:HGNC:26776|Ensembl:ENSG00000164329|Vega:OTTHUMG00000108163 +167227 DCP2 MIM:609844|HGNC:HGNC:24452|Ensembl:ENSG00000172795|Vega:OTTHUMG00000162853 +167359 NIM1K HGNC:HGNC:28646|Ensembl:ENSG00000177453|Vega:OTTHUMG00000131147 +167410 LIX1 MIM:610466|HGNC:HGNC:18581|Ensembl:ENSG00000145721|Vega:OTTHUMG00000128720 +167465 ZNF366 MIM:610159|HGNC:HGNC:18316|Ensembl:ENSG00000178175|Vega:OTTHUMG00000100965 +167555 FAM151B HGNC:HGNC:33716|Ensembl:ENSG00000152380|Vega:OTTHUMG00000131303 +167681 PRSS35 HGNC:HGNC:21387|Ensembl:ENSG00000146250|Vega:OTTHUMG00000015113 +167691 LCA5 MIM:611408|HGNC:HGNC:31923|Ensembl:ENSG00000135338|Vega:OTTHUMG00000015080 +167826 OLIG3 MIM:609323|HGNC:HGNC:18003|Ensembl:ENSG00000177468|Vega:OTTHUMG00000015657 +167838 TXLNB MIM:611438|HGNC:HGNC:21617|Ensembl:ENSG00000164440|Vega:OTTHUMG00000015688 +168002 DACT2 MIM:608966|HGNC:HGNC:21231|Ensembl:ENSG00000164488|Vega:OTTHUMG00000016046 +168090 C6orf118 HGNC:HGNC:21233|Ensembl:ENSG00000112539|Vega:OTTHUMG00000015984 +168330 PRSS3P1 HGNC:HGNC:43787 +168374 ZNF92 MIM:603974|HGNC:HGNC:13168|Ensembl:ENSG00000146757|Vega:OTTHUMG00000156557 +168391 GALNTL5 MIM:615133|HGNC:HGNC:21725|Ensembl:ENSG00000106648|Vega:OTTHUMG00000157306 +168400 DDX53 HGNC:HGNC:20083|Ensembl:ENSG00000184735|Vega:OTTHUMG00000021248 +168417 ZNF679 HGNC:HGNC:28650|Ensembl:ENSG00000197123|Vega:OTTHUMG00000156486 +168433 RNF133 HGNC:HGNC:21154|Ensembl:ENSG00000188050|Vega:OTTHUMG00000157092 +168448 CDC14C HGNC:HGNC:22427 +168451 THAP5 MIM:612534|HGNC:HGNC:23188|Ensembl:ENSG00000177683|Vega:OTTHUMG00000154951 +168455 CCDC71L HGNC:HGNC:26685|Ensembl:ENSG00000253276|Vega:OTTHUMG00000164150 +168474 SEPHS1P1 HGNC:HGNC:42161 +168507 PKD1L1 MIM:609721|HGNC:HGNC:18053|Ensembl:ENSG00000158683|Vega:OTTHUMG00000155649 +168537 GIMAP7 MIM:616961|HGNC:HGNC:22404|Ensembl:ENSG00000179144|Vega:OTTHUMG00000157626 +168544 ZNF467 MIM:614040|HGNC:HGNC:23154|Ensembl:ENSG00000181444|Vega:OTTHUMG00000157883 +168620 BHLHA15 MIM:608606|HGNC:HGNC:22265|Ensembl:ENSG00000180535|Vega:OTTHUMG00000154289 +168667 BMPER MIM:608699|HGNC:HGNC:24154|Ensembl:ENSG00000164619|Vega:OTTHUMG00000128675 +168741 PER4 - +168850 ZNF800 HGNC:HGNC:27267|Ensembl:ENSG00000048405|Vega:OTTHUMG00000023456 +168975 CNBD1 HGNC:HGNC:26663|Ensembl:ENSG00000176571|Vega:OTTHUMG00000163743 +169026 SLC30A8 MIM:611145|HGNC:HGNC:20303|Ensembl:ENSG00000164756|Vega:OTTHUMG00000164962 +169044 COL22A1 MIM:610026|HGNC:HGNC:22989|Ensembl:ENSG00000169436|Vega:OTTHUMG00000150035 +169166 SNX31 HGNC:HGNC:28605|Ensembl:ENSG00000174226|Vega:OTTHUMG00000164725 +169200 TMEM64 HGNC:HGNC:25441|Ensembl:ENSG00000180694|Vega:OTTHUMG00000157185 +169270 ZNF596 HGNC:HGNC:27268|Ensembl:ENSG00000172748|Vega:OTTHUMG00000086931 +169355 IDO2 MIM:612129|HGNC:HGNC:27269|Ensembl:ENSG00000188676|Vega:OTTHUMG00000141271 +169436 STKLD1 HGNC:HGNC:28669|Ensembl:ENSG00000198870|Vega:OTTHUMG00000020862 +169522 KCNV2 MIM:607604|HGNC:HGNC:19698|Ensembl:ENSG00000168263|Vega:OTTHUMG00000019449 +169611 OLFML2A MIM:615899|HGNC:HGNC:27270|Ensembl:ENSG00000185585|Vega:OTTHUMG00000020663 +169693 TMEM252 HGNC:HGNC:28537|Ensembl:ENSG00000181778|Vega:OTTHUMG00000019967 +169714 QSOX2 MIM:612860|HGNC:HGNC:30249|Ensembl:ENSG00000165661|Vega:OTTHUMG00000020923 +169792 GLIS3 MIM:610192|HGNC:HGNC:28510|Ensembl:ENSG00000107249|Vega:OTTHUMG00000019463 +169834 ZNF883 HGNC:HGNC:27271|Ensembl:ENSG00000228623 +169841 ZNF169 MIM:603404|HGNC:HGNC:12957|Ensembl:ENSG00000175787|Vega:OTTHUMG00000020264 +169966 FAM46D MIM:300976|HGNC:HGNC:28399|Ensembl:ENSG00000174016|Vega:OTTHUMG00000021902 +169981 SPIN3 HGNC:HGNC:27272|Ensembl:ENSG00000204271|Vega:OTTHUMG00000021677 +170062 FAM47B HGNC:HGNC:26659|Ensembl:ENSG00000189132|Vega:OTTHUMG00000021345 +170067 SUPT20HL2 HGNC:HGNC:31797 +170082 TCEANC HGNC:HGNC:28277|Ensembl:ENSG00000176896|Vega:OTTHUMG00000021154 +170261 ZCCHC12 MIM:300701|HGNC:HGNC:27273|Ensembl:ENSG00000174460|Vega:OTTHUMG00000022261 +170302 ARX MIM:300382|HGNC:HGNC:18060|Ensembl:ENSG00000004848|Vega:OTTHUMG00000021275 +170370 FAM170B HGNC:HGNC:19736|Ensembl:ENSG00000172538|Vega:OTTHUMG00000018187 +170371 C10orf128 HGNC:HGNC:27274|Ensembl:ENSG00000204161|Vega:OTTHUMG00000018188 +170384 FUT11 MIM:616932|HGNC:HGNC:19233|Ensembl:ENSG00000196968|Vega:OTTHUMG00000018483 +170392 OIT3 MIM:609330|HGNC:HGNC:29953|Ensembl:ENSG00000138315|Vega:OTTHUMG00000018444 +170393 C10orf91 HGNC:HGNC:27275 +170394 PWWP2B HGNC:HGNC:25150|Ensembl:ENSG00000171813|Vega:OTTHUMG00000019286 +170425 LINC00858 HGNC:HGNC:27276|Ensembl:ENSG00000229404 +170463 SSBP4 MIM:607391|HGNC:HGNC:15676|Ensembl:ENSG00000130511|Vega:OTTHUMG00000183362 +170474 HFM MIM:164210 +170482 CLEC4C MIM:606677|HGNC:HGNC:13258|Ensembl:ENSG00000198178|Vega:OTTHUMG00000168441 +170485 ARF4P2 HGNC:HGNC:16599 +170487 ACTL10 HGNC:HGNC:16127|Ensembl:ENSG00000182584|Vega:OTTHUMG00000032262 +170503 CDC42P1 HGNC:HGNC:16339 +170504 COX6CP2 HGNC:HGNC:16600 +170506 DHX36 MIM:612767|HGNC:HGNC:14410|Ensembl:ENSG00000174953|Vega:OTTHUMG00000159109 +170507 DFNA52 MIM:607683|HGNC:HGNC:15821 +170508 DFNB33 MIM:607239|HGNC:HGNC:16359 +170510 EIF4EBP2P1 HGNC:HGNC:16596 +170511 ENSAP1 HGNC:HGNC:16588 +170513 FAT1P1 HGNC:HGNC:16582 +170514 FTLP1 HGNC:HGNC:16547 +170516 GAPDHP2 HGNC:HGNC:16577 +170517 GCNT1P1 HGNC:HGNC:16532 +170522 GLRXP1 HGNC:HGNC:16544 +170523 GSTM3P1 HGNC:HGNC:16606 +170524 HNRNPA1P3 HGNC:HGNC:16567 +170526 HNRNPA3P2 HGNC:HGNC:16605 +170527 KRT18P3 HGNC:HGNC:16540 +170529 RPSAP1 HGNC:HGNC:16560 +170530 MRX78 MIM:300551|HGNC:HGNC:17942 +170532 OTSC3 MIM:608244|HGNC:HGNC:17831 +170533 PA2G4P2 HGNC:HGNC:16531 +170534 PARK10 MIM:606852|HGNC:HGNC:17833 +170535 PGAM3P HGNC:HGNC:16557 +170536 PPIAP21 HGNC:HGNC:16246 +170537 PPIAP2 HGNC:HGNC:16542 +170539 PPIAP3 HGNC:HGNC:16545 +170540 PPIAP17 HGNC:HGNC:16334 +170541 PSMD10P1 HGNC:HGNC:16602 +170542 PTMAP6 HGNC:HGNC:16573 +170543 RNF11P2 HGNC:HGNC:16535 +170547 AIMP1P1 HGNC:HGNC:16543 +170548 SF3A3P1 HGNC:HGNC:16576 +170550 SNRPFP1 HGNC:HGNC:16551 +170552 SRMP1 HGNC:HGNC:16552 +170554 DYNLT3P1 HGNC:HGNC:16571 +170555 TPM3P2 HGNC:HGNC:16556 +170556 UBE2V1P1 HGNC:HGNC:16581 +170559 XPOTP1 HGNC:HGNC:16586 +170572 HTR3C MIM:610121|HGNC:HGNC:24003|Ensembl:ENSG00000178084|Vega:OTTHUMG00000156862 +170575 GIMAP1 MIM:608084|HGNC:HGNC:23237|Ensembl:ENSG00000213203|Vega:OTTHUMG00000157489 +170589 GPHA2 MIM:609651|HGNC:HGNC:18054|Ensembl:ENSG00000149735|Vega:OTTHUMG00000165631 +170591 S100Z MIM:610103|HGNC:HGNC:30367|Ensembl:ENSG00000171643|Vega:OTTHUMG00000162441 +170592 UVM1 MIM:606660 +170593 UVM2 MIM:606661 +170594 WS2C MIM:606662 +170595 IBD8 MIM:606668|HGNC:HGNC:20235 +170622 COMMD6 MIM:612377|HGNC:HGNC:24015|Ensembl:ENSG00000188243|Vega:OTTHUMG00000017089 +170626 XAGE3 MIM:300740|HGNC:HGNC:14618|Ensembl:ENSG00000171402|Vega:OTTHUMG00000021587 +170627 XAGE5 HGNC:HGNC:30930|Ensembl:ENSG00000171405|Vega:OTTHUMG00000021589 +170679 PSORS1C1 MIM:613525|HGNC:HGNC:17202|Ensembl:ENSG00000204540|Vega:OTTHUMG00000031077 +170680 PSORS1C2 MIM:613526|HGNC:HGNC:17199|Ensembl:ENSG00000204538|Vega:OTTHUMG00000031081 +170682 SLEH1 MIM:607279|HGNC:HGNC:17420 +170685 NUDT10 MIM:300527|HGNC:HGNC:17621|Ensembl:ENSG00000122824|Vega:OTTHUMG00000021530 +170688 NUDT4P2 HGNC:HGNC:18013 +170689 ADAMTS15 MIM:607509|HGNC:HGNC:16305|Ensembl:ENSG00000166106|Vega:OTTHUMG00000165657 +170690 ADAMTS16 MIM:607510|HGNC:HGNC:17108|Ensembl:ENSG00000145536|Vega:OTTHUMG00000161663 +170691 ADAMTS17 MIM:607511|HGNC:HGNC:17109|Ensembl:ENSG00000140470|Vega:OTTHUMG00000149867 +170692 ADAMTS18 MIM:607512|HGNC:HGNC:17110|Ensembl:ENSG00000140873|Vega:OTTHUMG00000137619 +170712 COX7B2 MIM:609811|HGNC:HGNC:24381|Ensembl:ENSG00000170516|Vega:OTTHUMG00000099423 +170815 BMIQ1 MIM:606641|HGNC:HGNC:23827 +170825 GSX2 MIM:616253|HGNC:HGNC:24959|Ensembl:ENSG00000180613|Vega:OTTHUMG00000128696 +170850 KCNG3 MIM:606767|HGNC:HGNC:18306|Ensembl:ENSG00000171126|Vega:OTTHUMG00000128604 +170949 DEFT1P HGNC:HGNC:18339|Ensembl:ENSG00000215378 +170954 PPP1R18 MIM:610990|HGNC:HGNC:29413|Ensembl:ENSG00000146112|Vega:OTTHUMG00000031237 +170958 ZNF525 HGNC:HGNC:29423|Ensembl:ENSG00000203326|Vega:OTTHUMG00000158277 +170959 ZNF431 HGNC:HGNC:20809|Ensembl:ENSG00000196705|Vega:OTTHUMG00000182835 +170960 ZNF721 HGNC:HGNC:29425|Ensembl:ENSG00000182903|Vega:OTTHUMG00000112450 +170961 ANKRD24 HGNC:HGNC:29424|Ensembl:ENSG00000089847|Vega:OTTHUMG00000181865 +171013 SLI1 MIM:606711 +171014 SLI2 MIM:606712 +171017 ZNF384 MIM:609951|HGNC:HGNC:11955|Ensembl:ENSG00000126746|Vega:OTTHUMG00000168716 +171019 ADAMTS19 MIM:607513|HGNC:HGNC:17111|Ensembl:ENSG00000145808|Vega:OTTHUMG00000128990 +171022 ABHD11-AS1 MIM:612545|HGNC:HGNC:18289|Ensembl:ENSG00000225969 +171023 ASXL1 MIM:612990|HGNC:HGNC:18318|Ensembl:ENSG00000171456|Vega:OTTHUMG00000032218 +171024 SYNPO2 HGNC:HGNC:17732|Ensembl:ENSG00000172403|Vega:OTTHUMG00000161165 +171089 DYX5 MIM:606896|HGNC:HGNC:18343 +171157 SHFM5 MIM:606708|HGNC:HGNC:35421 +171169 SPACA4 MIM:609932|HGNC:HGNC:16441|Ensembl:ENSG00000177202|Vega:OTTHUMG00000183316 +171176 NICN2P HGNC:HGNC:18322 +171177 RHOV HGNC:HGNC:18313|Ensembl:ENSG00000104140|Vega:OTTHUMG00000130134 +171220 DSTNP2 HGNC:HGNC:34546|Ensembl:ENSG00000248593 +171221 DNAJB1P1 HGNC:HGNC:24988 +171222 UBE2L5P HGNC:HGNC:13477 +171389 NLRP6 MIM:609650|HGNC:HGNC:22944|Ensembl:ENSG00000174885|Vega:OTTHUMG00000119070 +171391 LOC171391 Ensembl:ENSG00000255284 +171392 ZNF675 HGNC:HGNC:30768|Ensembl:ENSG00000197372|Vega:OTTHUMG00000183384 +171416 TXNP2 HGNC:HGNC:49482 +171417 LOC171417 - +171418 GLRXP2 HGNC:HGNC:18376 +171419 TXNP3 HGNC:HGNC:49483 +171420 HSPE1P28 HGNC:HGNC:49347 +171421 HSPE1P16 HGNC:HGNC:49334 +171422 CRPP1 HGNC:HGNC:2368 +171423 PDIA3P1 HGNC:HGNC:4607 +171424 SPA17P1 HGNC:HGNC:23224 +171425 CLYBL MIM:609686|HGNC:HGNC:18355|Ensembl:ENSG00000125246|Vega:OTTHUMG00000017278 +171427 CYP2F2P HGNC:HGNC:18851 +171472 SRSF10P2 HGNC:HGNC:24823 +171482 FAM9A MIM:300477|HGNC:HGNC:18403|Ensembl:ENSG00000183304|Vega:OTTHUMG00000021110 +171483 FAM9B MIM:300478|HGNC:HGNC:18404|Ensembl:ENSG00000177138|Vega:OTTHUMG00000021114 +171484 FAM9C MIM:300479|HGNC:HGNC:18405|Ensembl:ENSG00000187268|Vega:OTTHUMG00000021143 +171511 ADIPQTL2 MIM:606770 +171512 ADIPQTL3 MIM:606771 +171513 PAOD1 MIM:606787 +171514 ANON1 MIM:606788 +171515 HBFQTL4 MIM:606789 +171523 CYP2T1P HGNC:HGNC:18852 +171546 SPTSSA MIM:613540|HGNC:HGNC:20361|Ensembl:ENSG00000165389|Vega:OTTHUMG00000140212 +171558 PTCRA MIM:606817|HGNC:HGNC:21290|Ensembl:ENSG00000171611|Vega:OTTHUMG00000014709 +171559 HMGA1P2 HGNC:HGNC:13322 +171560 TXNP6 HGNC:HGNC:49486 +171568 POLR3H HGNC:HGNC:30349|Ensembl:ENSG00000100413|Vega:OTTHUMG00000150971 +171586 ABHD3 MIM:612197|HGNC:HGNC:18718|Ensembl:ENSG00000158201|Vega:OTTHUMG00000179099 +191585 PLAC4 MIM:613770|HGNC:HGNC:14616 +192111 PGAM5 MIM:614939|HGNC:HGNC:28763|Ensembl:ENSG00000247077|Vega:OTTHUMG00000168021 +192115 MGR1 MIM:157300 +192127 SLC20A1P1 HGNC:HGNC:20051 +192128 SLC20A1P2 HGNC:HGNC:42539 +192130 GOLGA4P3 HGNC:HGNC:43786 +192131 GOLGA4P1 HGNC:HGNC:18660 +192132 GOLGA4P2 HGNC:HGNC:20727 +192133 RPS8P1 HGNC:HGNC:19789 +192134 B3GNT6 MIM:615315|HGNC:HGNC:24141|Ensembl:ENSG00000198488|Vega:OTTHUMG00000181633 +192142 RLS1 MIM:102300 +192143 STQTL2 MIM:606256 +192144 HDLCQ1 MIM:606613|HGNC:HGNC:30996 +192146 DDX50P1 HGNC:HGNC:18974 +192149 BMIQ2 MIM:606643|HGNC:HGNC:23828 +192217 OXCT2P1 HGNC:HGNC:21627|Ensembl:ENSG00000237624 +192286 HIGD2A HGNC:HGNC:28311|Ensembl:ENSG00000146066|Vega:OTTHUMG00000130657 +192343 NEWENTRY - +192644 DFNA21 MIM:607017|HGNC:HGNC:2794 +192666 KRT24 MIM:607742|HGNC:HGNC:18527|Ensembl:ENSG00000167916|Vega:OTTHUMG00000133372 +192668 CYS1 HGNC:HGNC:18525|Ensembl:ENSG00000205795|Vega:OTTHUMG00000151703 +192669 AGO3 MIM:607355|HGNC:HGNC:18421|Ensembl:ENSG00000126070|Vega:OTTHUMG00000184172 +192670 AGO4 MIM:607356|HGNC:HGNC:18424|Ensembl:ENSG00000134698|Vega:OTTHUMG00000004243 +192676 DFNA43 MIM:608394|HGNC:HGNC:17243 +192677 SLEN1 MIM:607965|HGNC:HGNC:18542 +192679 SLEN2 MIM:607966|HGNC:HGNC:18543 +192683 SCAMP5 MIM:613766|HGNC:HGNC:30386|Ensembl:ENSG00000198794|Vega:OTTHUMG00000172704 +193629 LINC00189 HGNC:HGNC:18461|Ensembl:ENSG00000215533 +195814 SDR16C5 MIM:608989|HGNC:HGNC:30311|Ensembl:ENSG00000170786|Vega:OTTHUMG00000164311 +195827 AAED1 HGNC:HGNC:16881|Ensembl:ENSG00000158122|Vega:OTTHUMG00000020299 +195828 ZNF367 MIM:610160|HGNC:HGNC:18320|Ensembl:ENSG00000165244|Vega:OTTHUMG00000020295 +195977 ANTXRL HGNC:HGNC:27277|Ensembl:ENSG00000274209|Vega:OTTHUMG00000188318 +196047 EMX2OS MIM:607637|HGNC:HGNC:18511|Ensembl:ENSG00000229847 +196051 PLPP4 HGNC:HGNC:23531|Ensembl:ENSG00000203805|Vega:OTTHUMG00000019168 +196074 METTL15 HGNC:HGNC:26606|Ensembl:ENSG00000169519|Vega:OTTHUMG00000150448 +196120 SSU72P5 HGNC:HGNC:43624 +196188 RPS2P38 HGNC:HGNC:36584 +196264 MPZL3 MIM:611707|HGNC:HGNC:27279|Ensembl:ENSG00000160588|Vega:OTTHUMG00000166966 +196294 IMMP1L MIM:612323|HGNC:HGNC:26317|Ensembl:ENSG00000148950|Vega:OTTHUMG00000166226 +196335 OR56B4 HGNC:HGNC:15248|Ensembl:ENSG00000180919|Vega:OTTHUMG00000165531 +196374 KRT78 MIM:611159|HGNC:HGNC:28926|Ensembl:ENSG00000170423|Vega:OTTHUMG00000169880 +196383 RILPL2 MIM:614093|HGNC:HGNC:28787|Ensembl:ENSG00000150977|Vega:OTTHUMG00000187294 +196385 DNAH10 MIM:605884|HGNC:HGNC:2941|Ensembl:ENSG00000197653|Vega:OTTHUMG00000154477 +196394 AMN1 HGNC:HGNC:27281|Ensembl:ENSG00000151743|Vega:OTTHUMG00000169192 +196403 DTX3 MIM:613142|HGNC:HGNC:24457|Ensembl:ENSG00000178498|Vega:OTTHUMG00000170189 +196410 METTL7B HGNC:HGNC:28276|Ensembl:ENSG00000170439|Vega:OTTHUMG00000152665 +196415 C12orf77 HGNC:HGNC:27282 +196441 ZFC3H1 HGNC:HGNC:28328|Ensembl:ENSG00000133858|Vega:OTTHUMG00000169545 +196446 MYRFL HGNC:HGNC:26316|Ensembl:ENSG00000166268|Vega:OTTHUMG00000169438 +196463 PLBD2 HGNC:HGNC:27283|Ensembl:ENSG00000151176|Vega:OTTHUMG00000169567 +196469 LOC196469 - +196472 FAM71C HGNC:HGNC:28594|Ensembl:ENSG00000180219|Vega:OTTHUMG00000170311 +196475 RMST MIM:607045|HGNC:HGNC:29893|Ensembl:ENSG00000255794 +196477 CCER1 HGNC:HGNC:28373|Ensembl:ENSG00000197651|Vega:OTTHUMG00000170070 +196483 EEF2KMT MIM:615263|HGNC:HGNC:32221|Ensembl:ENSG00000118894|Vega:OTTHUMG00000129527 +196500 PIANP MIM:616065|HGNC:HGNC:25338|Ensembl:ENSG00000139200|Vega:OTTHUMG00000168664 +196513 DCP1B MIM:609843|HGNC:HGNC:24451|Ensembl:ENSG00000151065|Vega:OTTHUMG00000168113 +196527 ANO6 MIM:608663|HGNC:HGNC:25240|Ensembl:ENSG00000177119|Vega:OTTHUMG00000169564 +196528 ARID2 MIM:609539|HGNC:HGNC:18037|Ensembl:ENSG00000189079|Vega:OTTHUMG00000150487 +196541 METTL21C MIM:615259|HGNC:HGNC:33717|Ensembl:ENSG00000139780|Vega:OTTHUMG00000017304 +196549 EEF1DP3 HGNC:HGNC:30486 +196740 VSTM4 HGNC:HGNC:26470|Ensembl:ENSG00000165633|Vega:OTTHUMG00000018184 +196743 PAOX MIM:615853|HGNC:HGNC:20837|Ensembl:ENSG00000148832|Vega:OTTHUMG00000019318 +196792 FAM24B HGNC:HGNC:23475|Ensembl:ENSG00000213185|Vega:OTTHUMG00000019194 +196872 LINC00638 HGNC:HGNC:28325|Ensembl:ENSG00000258701 +196883 ADCY4 MIM:600292|HGNC:HGNC:235|Ensembl:ENSG00000129467|Vega:OTTHUMG00000029347 +196913 LINC01599 HGNC:HGNC:27285 +196951 FAM227B HGNC:HGNC:26543|Ensembl:ENSG00000166262|Vega:OTTHUMG00000172328 +196968 DNM1P46 HGNC:HGNC:35199|Ensembl:ENSG00000182397 +196993 CT62 HGNC:HGNC:27286|Ensembl:ENSG00000225362|Vega:OTTHUMG00000172836 +196996 GRAMD2A HGNC:HGNC:27287|Ensembl:ENSG00000175318|Vega:OTTHUMG00000172708 +197003 MGC15885 Ensembl:ENSG00000259458 +197021 LCTL MIM:617060|HGNC:HGNC:15583|Ensembl:ENSG00000188501|Vega:OTTHUMG00000133207 +197131 UBR1 MIM:605981|HGNC:HGNC:16808|Ensembl:ENSG00000159459|Vega:OTTHUMG00000130702 +197135 PATL2 MIM:614661|HGNC:HGNC:33630|Ensembl:ENSG00000229474|Vega:OTTHUMG00000171932 +197187 SNAI3-AS1 HGNC:HGNC:28327|Ensembl:ENSG00000260630 +197196 LINC00311 HGNC:HGNC:28312|Ensembl:ENSG00000179219 +197257 LDHD MIM:607490|HGNC:HGNC:19708|Ensembl:ENSG00000166816|Vega:OTTHUMG00000137605 +197258 FUK MIM:608675|HGNC:HGNC:29500|Ensembl:ENSG00000157353|Vega:OTTHUMG00000074085 +197259 MLKL MIM:615153|HGNC:HGNC:26617|Ensembl:ENSG00000168404|Vega:OTTHUMG00000177356 +197320 ZNF778 HGNC:HGNC:26479|Ensembl:ENSG00000170100|Vega:OTTHUMG00000175526 +197322 ACSF3 MIM:614245|HGNC:HGNC:27288|Ensembl:ENSG00000176715|Vega:OTTHUMG00000138044 +197331 TUBB8P7 HGNC:HGNC:42345 +197335 WDR90 HGNC:HGNC:26960|Ensembl:ENSG00000161996|Vega:OTTHUMG00000048040 +197342 EME2 MIM:610886|HGNC:HGNC:27289|Ensembl:ENSG00000197774|Vega:OTTHUMG00000176706 +197350 CASP16P HGNC:HGNC:27290|Ensembl:ENSG00000228146 +197358 NLRC3 MIM:615648|HGNC:HGNC:29889|Ensembl:ENSG00000167984|Vega:OTTHUMG00000177561 +197370 NSMCE1 MIM:617263|HGNC:HGNC:29897|Ensembl:ENSG00000169189|Vega:OTTHUMG00000131674 +197407 ZNF48 HGNC:HGNC:13114|Ensembl:ENSG00000180035|Vega:OTTHUMG00000048195 +198437 LKAAEAR1 HGNC:HGNC:33718|Ensembl:ENSG00000171695|Vega:OTTHUMG00000033021 +199221 DZIP1L MIM:617570|HGNC:HGNC:26551|Ensembl:ENSG00000158163|Vega:OTTHUMG00000159819 +199223 TTC21A MIM:611430|HGNC:HGNC:30761|Ensembl:ENSG00000168026|Vega:OTTHUMG00000155973 +199675 MCEMP1 MIM:609565|HGNC:HGNC:27291|Ensembl:ENSG00000183019|Vega:OTTHUMG00000182440 +199692 ZNF627 MIM:612248|HGNC:HGNC:30570|Ensembl:ENSG00000198551|Vega:OTTHUMG00000182035 +199699 DAND5 MIM:609068|HGNC:HGNC:26780|Ensembl:ENSG00000179284|Vega:OTTHUMG00000180725 +199704 ZNF585A HGNC:HGNC:26305|Ensembl:ENSG00000196967|Vega:OTTHUMG00000181857 +199713 NLRP7 MIM:609661|HGNC:HGNC:22947|Ensembl:ENSG00000167634|Vega:OTTHUMG00000180428 +199720 GGN MIM:609966|HGNC:HGNC:18869|Ensembl:ENSG00000179168|Vega:OTTHUMG00000182080 +199731 CADM4 MIM:609744|HGNC:HGNC:30825|Ensembl:ENSG00000105767|Vega:OTTHUMG00000182735 +199745 THAP8 MIM:612536|HGNC:HGNC:23191|Ensembl:ENSG00000161277|Vega:OTTHUMG00000048138 +199746 U2AF1L4 MIM:601080|HGNC:HGNC:23020|Ensembl:ENSG00000161265|Vega:OTTHUMG00000182066 +199777 ZNF626 HGNC:HGNC:30461|Ensembl:ENSG00000188171|Vega:OTTHUMG00000179733 +199786 FAM129C MIM:609967|HGNC:HGNC:24130|Ensembl:ENSG00000167483|Vega:OTTHUMG00000182892 +199800 ADM5 HGNC:HGNC:27293|Ensembl:ENSG00000224420|Vega:OTTHUMG00000183240 +199827 RNASEH1P3 HGNC:HGNC:18716 +199834 LCE4A MIM:612618|HGNC:HGNC:16613|Ensembl:ENSG00000187170|Vega:OTTHUMG00000014394 +199857 ALG14 MIM:612866|HGNC:HGNC:28287|Ensembl:ENSG00000172339|Vega:OTTHUMG00000010781 +199870 FAM76A HGNC:HGNC:28530|Ensembl:ENSG00000009780|Vega:OTTHUMG00000003729 +199882 LOC199882 - +199899 LINC00466 HGNC:HGNC:27294|Ensembl:ENSG00000224209 +199900 MRPS21P1 HGNC:HGNC:29748 +199920 FYB2 HGNC:HGNC:27295|Ensembl:ENSG00000187889|Vega:OTTHUMG00000008281 +199953 TMEM201 HGNC:HGNC:33719|Ensembl:ENSG00000188807|Vega:OTTHUMG00000057457 +199964 TMEM61 HGNC:HGNC:27296|Ensembl:ENSG00000143001|Vega:OTTHUMG00000009991 +199974 CYP4Z1 HGNC:HGNC:20583|Ensembl:ENSG00000186160|Vega:OTTHUMG00000008019 +199990 FAAP20 MIM:615183|HGNC:HGNC:26428|Ensembl:ENSG00000162585|Vega:OTTHUMG00000001404 +200008 CDCP2 MIM:612320|HGNC:HGNC:27297|Ensembl:ENSG00000157211|Vega:OTTHUMG00000155307 +200010 SLC5A9 HGNC:HGNC:22146|Ensembl:ENSG00000117834|Vega:OTTHUMG00000007959 +200014 CC2D1B HGNC:HGNC:29386|Ensembl:ENSG00000154222|Vega:OTTHUMG00000008102 +200025 PFN1P3 HGNC:HGNC:42987 +200030 NBPF11 MIM:614001|HGNC:HGNC:31993|Ensembl:ENSG00000263956|Vega:OTTHUMG00000013880 +200035 NUDT17 HGNC:HGNC:26618|Ensembl:ENSG00000186364|Vega:OTTHUMG00000013752 +200058 FLJ23867 - +200081 TXLNA MIM:608676|HGNC:HGNC:30685|Ensembl:ENSG00000084652|Vega:OTTHUMG00000004423 +200132 TCTEX1D1 HGNC:HGNC:26882|Ensembl:ENSG00000152760|Vega:OTTHUMG00000009162 +200149 TUBB8P6 HGNC:HGNC:42343 +200150 PLD5 HGNC:HGNC:26879|Ensembl:ENSG00000180287|Vega:OTTHUMG00000039867 +200159 C1orf100 HGNC:HGNC:30435|Ensembl:ENSG00000173728|Vega:OTTHUMG00000040104 +200162 SPAG17 MIM:616554|HGNC:HGNC:26620|Ensembl:ENSG00000155761|Vega:OTTHUMG00000012198 +200172 SLFNL1 HGNC:HGNC:26313|Ensembl:ENSG00000171790|Vega:OTTHUMG00000005719 +200185 KRTCAP2 HGNC:HGNC:28942|Ensembl:ENSG00000163463|Vega:OTTHUMG00000013904 +200186 CRTC2 MIM:608972|HGNC:HGNC:27301|Ensembl:ENSG00000160741|Vega:OTTHUMG00000037156 +200197 TMEM51-AS1 HGNC:HGNC:26301|Ensembl:ENSG00000175147 +200205 IBA57 MIM:615316|HGNC:HGNC:27302|Ensembl:ENSG00000181873|Vega:OTTHUMG00000039769 +200232 FAM209A HGNC:HGNC:16100|Ensembl:ENSG00000124103|Vega:OTTHUMG00000032799 +200261 LINC00656 HGNC:HGNC:27304|Ensembl:ENSG00000233746 +200298 LINC00528 HGNC:HGNC:26875|Ensembl:ENSG00000269220 +200312 RNF215 HGNC:HGNC:33434|Ensembl:ENSG00000099999|Vega:OTTHUMG00000151016 +200315 APOBEC3A MIM:607109|HGNC:HGNC:17343|Ensembl:ENSG00000128383|Vega:OTTHUMG00000151004 +200316 APOBEC3F MIM:608993|HGNC:HGNC:17356|Ensembl:ENSG00000128394|Vega:OTTHUMG00000151080 +200350 FOXD4L1 MIM:611084|HGNC:HGNC:18521|Ensembl:ENSG00000184492|Vega:OTTHUMG00000131359 +200373 CFAP221 HGNC:HGNC:33720|Ensembl:ENSG00000163075|Vega:OTTHUMG00000153310 +200403 VWA3B MIM:614884|HGNC:HGNC:28385|Ensembl:ENSG00000168658|Vega:OTTHUMG00000153104 +200407 CREG2 HGNC:HGNC:14272|Ensembl:ENSG00000175874|Vega:OTTHUMG00000130692 +200420 ALMS1P1 HGNC:HGNC:29586|Ensembl:ENSG00000163016 +200424 TET3 MIM:613555|HGNC:HGNC:28313|Ensembl:ENSG00000187605|Vega:OTTHUMG00000152823 +200504 GKN2 HGNC:HGNC:24588|Ensembl:ENSG00000183607|Vega:OTTHUMG00000152655 +200523 TEX37 HGNC:HGNC:26341|Ensembl:ENSG00000172073|Vega:OTTHUMG00000130332 +200539 ANKRD23 MIM:610736|HGNC:HGNC:24470|Ensembl:ENSG00000163126|Vega:OTTHUMG00000130534 +200558 APLF MIM:611035|HGNC:HGNC:28724|Ensembl:ENSG00000169621|Vega:OTTHUMG00000129566 +200575 CRYGEP HGNC:HGNC:2412 +200576 PIKFYVE MIM:609414|HGNC:HGNC:23785|Ensembl:ENSG00000115020|Vega:OTTHUMG00000132945 +200634 KRTCAP3 HGNC:HGNC:28943|Ensembl:ENSG00000157992|Vega:OTTHUMG00000097782 +200726 FAM237A HGNC:HGNC:52388|Ensembl:ENSG00000235118|Vega:OTTHUMG00000154723 +200728 TMEM17 MIM:614950|HGNC:HGNC:26623|Ensembl:ENSG00000186889|Vega:OTTHUMG00000129455 +200734 SPRED2 MIM:609292|HGNC:HGNC:17722|Ensembl:ENSG00000198369|Vega:OTTHUMG00000152737 +200765 TIGD1 MIM:612972|HGNC:HGNC:14523|Ensembl:ENSG00000221944|Vega:OTTHUMG00000133260 +200772 LOC200772 Ensembl:ENSG00000233392 +200810 ALG1L HGNC:HGNC:33721|Ensembl:ENSG00000189366|Vega:OTTHUMG00000159588 +200844 C3orf67 HGNC:HGNC:24763|Ensembl:ENSG00000163689|Vega:OTTHUMG00000159151 +200845 KCTD6 HGNC:HGNC:22235|Ensembl:ENSG00000168301|Vega:OTTHUMG00000159161 +200879 LIPH MIM:607365|HGNC:HGNC:18483|Ensembl:ENSG00000163898|Vega:OTTHUMG00000156657 +200894 ARL13B MIM:608922|HGNC:HGNC:25419|Ensembl:ENSG00000169379|Vega:OTTHUMG00000159012 +200895 DHFR2 MIM:616588|HGNC:HGNC:27309|Ensembl:ENSG00000178700|Vega:OTTHUMG00000159014 +200909 HTR3D MIM:610122|HGNC:HGNC:24004|Ensembl:ENSG00000186090|Vega:OTTHUMG00000156858 +200916 RPL22L1 HGNC:HGNC:27610|Ensembl:ENSG00000163584|Vega:OTTHUMG00000158957 +200931 SLC51A MIM:612084|HGNC:HGNC:29955|Ensembl:ENSG00000163959|Vega:OTTHUMG00000155684 +200933 FBXO45 MIM:609112|HGNC:HGNC:29148|Ensembl:ENSG00000174013|Vega:OTTHUMG00000155571 +200942 KLHDC8B MIM:613169|HGNC:HGNC:28557|Ensembl:ENSG00000185909|Vega:OTTHUMG00000156814 +200958 MUC20 MIM:610360|HGNC:HGNC:23282|Ensembl:ENSG00000176945|Vega:OTTHUMG00000155823 +200959 GABRR3 HGNC:HGNC:17969|Ensembl:ENSG00000183185|Vega:OTTHUMG00000159135 +201134 CEP112 HGNC:HGNC:28514|Ensembl:ENSG00000154240|Vega:OTTHUMG00000179474 +201140 DHRS7C MIM:616161|HGNC:HGNC:32423|Ensembl:ENSG00000184544|Vega:OTTHUMG00000177944 +201158 TVP23C HGNC:HGNC:30453|Ensembl:ENSG00000175106|Vega:OTTHUMG00000171461 +201161 CENPV MIM:608139|HGNC:HGNC:29920|Ensembl:ENSG00000166582|Vega:OTTHUMG00000059345 +201163 FLCN MIM:607273|HGNC:HGNC:27310|Ensembl:ENSG00000154803|Vega:OTTHUMG00000059275 +201164 PLD6 MIM:614960|HGNC:HGNC:30447|Ensembl:ENSG00000179598|Vega:OTTHUMG00000059278 +201176 ARHGAP27 MIM:610591|HGNC:HGNC:31813|Ensembl:ENSG00000159314|Vega:OTTHUMG00000166982 +201181 ZNF385C HGNC:HGNC:33722|Ensembl:ENSG00000187595|Ensembl:ENSG00000267221|Vega:OTTHUMG00000132073|Vega:OTTHUMG00000180103 +201191 SAMD14 HGNC:HGNC:27312|Ensembl:ENSG00000167100|Vega:OTTHUMG00000161992 +201229 LYRM9 HGNC:HGNC:27314|Ensembl:ENSG00000232859|Vega:OTTHUMG00000132829 +201232 SLC16A13 HGNC:HGNC:31037|Ensembl:ENSG00000174327|Vega:OTTHUMG00000102089 +201243 C17orf74 HGNC:HGNC:27315|Ensembl:ENSG00000184560|Vega:OTTHUMG00000178190 +201254 CENPX MIM:615128|HGNC:HGNC:11422|Ensembl:ENSG00000169689|Vega:OTTHUMG00000132129 +201255 LRRC45 HGNC:HGNC:28302|Ensembl:ENSG00000169683|Vega:OTTHUMG00000178454 +201259 RPL32P31 HGNC:HGNC:37035 +201266 SLC39A11 MIM:616508|HGNC:HGNC:14463|Ensembl:ENSG00000133195|Vega:OTTHUMG00000178306 +201283 AMZ2P1 HGNC:HGNC:26491|Ensembl:ENSG00000214174 +201288 NOS2P2 MIM:600719|HGNC:HGNC:7874 +201292 TRIM65 HGNC:HGNC:27316|Ensembl:ENSG00000141569|Vega:OTTHUMG00000132127 +201294 UNC13D MIM:608897|HGNC:HGNC:23147|Ensembl:ENSG00000092929|Vega:OTTHUMG00000179895 +201299 RDM1 MIM:612896|HGNC:HGNC:19950|Ensembl:ENSG00000278023|Vega:OTTHUMG00000188399 +201305 SPNS3 MIM:611701|HGNC:HGNC:28433|Ensembl:ENSG00000182557|Vega:OTTHUMG00000177737 +201456 FBXO15 MIM:609093|HGNC:HGNC:13617|Ensembl:ENSG00000141665|Vega:OTTHUMG00000132842 +201475 RAB12 MIM:616448|HGNC:HGNC:31332|Ensembl:ENSG00000206418|Vega:OTTHUMG00000178949 +201477 DLGAP1-AS3 HGNC:HGNC:27317|Ensembl:ENSG00000263724 +201501 ZBTB7C MIM:616591|HGNC:HGNC:31700|Ensembl:ENSG00000184828|Vega:OTTHUMG00000180322 +201514 ZNF584 HGNC:HGNC:27318|Ensembl:ENSG00000171574|Vega:OTTHUMG00000183533 +201516 ZSCAN4 MIM:613419|HGNC:HGNC:23709|Ensembl:ENSG00000180532|Vega:OTTHUMG00000183474 +201562 HACD2 MIM:615939|HGNC:HGNC:9640|Ensembl:ENSG00000206527|Vega:OTTHUMG00000159529 +201595 STT3B MIM:608605|HGNC:HGNC:30611|Ensembl:ENSG00000163527|Vega:OTTHUMG00000130673 +201617 LINC00870 HGNC:HGNC:27319|Ensembl:ENSG00000243083 +201625 DNAH12 MIM:603340|HGNC:HGNC:2943|Ensembl:ENSG00000174844|Vega:OTTHUMG00000158598 +201626 PDE12 MIM:616519|HGNC:HGNC:25386|Ensembl:ENSG00000174840|Vega:OTTHUMG00000158599 +201627 DENND6A HGNC:HGNC:26635|Ensembl:ENSG00000174839|Vega:OTTHUMG00000158639 +201633 TIGIT MIM:612859|HGNC:HGNC:26838|Ensembl:ENSG00000181847|Vega:OTTHUMG00000159331 +201651 AADACP1 HGNC:HGNC:50305|Ensembl:ENSG00000240602 +201725 C4orf46 MIM:616210|HGNC:HGNC:27320|Ensembl:ENSG00000205208|Vega:OTTHUMG00000161919 +201780 SLC10A4 HGNC:HGNC:22980|Ensembl:ENSG00000145248|Vega:OTTHUMG00000102092 +201798 TIGD4 HGNC:HGNC:18335|Ensembl:ENSG00000169989|Vega:OTTHUMG00000161464 +201799 TMEM154 HGNC:HGNC:26489|Ensembl:ENSG00000170006|Vega:OTTHUMG00000161463 +201853 LINC00504 HGNC:HGNC:43555|Ensembl:ENSG00000248360 +201895 SMIM14 HGNC:HGNC:27321|Ensembl:ENSG00000163683|Vega:OTTHUMG00000128581 +201931 TMEM192 HGNC:HGNC:26775|Ensembl:ENSG00000170088|Vega:OTTHUMG00000161254 +201965 RWDD4 HGNC:HGNC:23750|Ensembl:ENSG00000182552|Vega:OTTHUMG00000160632 +201973 PRIMPOL MIM:615421|HGNC:HGNC:26575|Ensembl:ENSG00000164306|Vega:OTTHUMG00000160495 +201989 GK6P HGNC:HGNC:23263 +202018 TAPT1 MIM:612758|HGNC:HGNC:26887|Ensembl:ENSG00000169762|Vega:OTTHUMG00000160177 +202020 TAPT1-AS1 HGNC:HGNC:26832|Ensembl:ENSG00000263327 +202051 SPATA24 HGNC:HGNC:27322|Ensembl:ENSG00000170469|Vega:OTTHUMG00000163388 +202052 DNAJC18 HGNC:HGNC:28429|Ensembl:ENSG00000170464|Vega:OTTHUMG00000129225 +202122 RPL27P10 HGNC:HGNC:35494 +202134 FAM153B HGNC:HGNC:27323|Ensembl:ENSG00000182230|Vega:OTTHUMG00000163181 +202151 RANBP3L MIM:616391|HGNC:HGNC:26353|Ensembl:ENSG00000164188|Vega:OTTHUMG00000131110 +202181 LOC202181 - +202227 LOC202227 - +202243 CCDC125 MIM:613781|HGNC:HGNC:28924|Ensembl:ENSG00000183323|Vega:OTTHUMG00000131259 +202299 LINC01554 HGNC:HGNC:24687|Ensembl:ENSG00000236882 +202309 GAPT HGNC:HGNC:26588|Ensembl:ENSG00000175857|Vega:OTTHUMG00000131219 +202319 LOC202319 - +202333 CMYA5 MIM:612193|HGNC:HGNC:14305|Ensembl:ENSG00000164309|Vega:OTTHUMG00000162548 +202374 STK32A HGNC:HGNC:28317|Ensembl:ENSG00000169302|Vega:OTTHUMG00000163411 +202459 OSTCP1 HGNC:HGNC:30530|Ensembl:ENSG00000243775 +202500 TCTE1 MIM:186975|HGNC:HGNC:11693|Ensembl:ENSG00000146221|Vega:OTTHUMG00000014763 +202559 KHDRBS2 MIM:610487|HGNC:HGNC:18114|Ensembl:ENSG00000112232|Vega:OTTHUMG00000014936 +202658 TRIM39-RPP21 HGNC:HGNC:38845|Ensembl:ENSG00000248167|Vega:OTTHUMG00000161144 +202781 PAXIP1-AS1 HGNC:HGNC:27328|Ensembl:ENSG00000273344 +202789 RPL17P27 HGNC:HGNC:36038 +202861 OR2A3P HGNC:HGNC:8231 +202865 C7orf33 HGNC:HGNC:21724|Ensembl:ENSG00000170279|Vega:OTTHUMG00000152756 +202915 TMEM184A HGNC:HGNC:28797|Ensembl:ENSG00000164855|Vega:OTTHUMG00000119025 +203054 ADCK5 HGNC:HGNC:21738|Ensembl:ENSG00000173137|Vega:OTTHUMG00000165190 +203062 TSNARE1 HGNC:HGNC:26437|Ensembl:ENSG00000171045|Vega:OTTHUMG00000164867 +203068 TUBB MIM:191130|HGNC:HGNC:20778|Ensembl:ENSG00000196230|Vega:OTTHUMG00000031059 +203069 R3HCC1 HGNC:HGNC:27329|Ensembl:ENSG00000104679|Vega:OTTHUMG00000163786 +203074 PRSS55 MIM:615144|HGNC:HGNC:30824|Ensembl:ENSG00000184647|Vega:OTTHUMG00000129345 +203076 C8orf74 HGNC:HGNC:32296|Ensembl:ENSG00000171060|Vega:OTTHUMG00000163807 +203100 HTRA4 MIM:610700|HGNC:HGNC:26909|Ensembl:ENSG00000169495|Vega:OTTHUMG00000164070 +203102 ADAM32 HGNC:HGNC:15479|Ensembl:ENSG00000197140|Vega:OTTHUMG00000164071 +203111 ERICH5 HGNC:HGNC:26823|Ensembl:ENSG00000177459|Vega:OTTHUMG00000164819 +203190 LGI3 MIM:608302|HGNC:HGNC:18711|Ensembl:ENSG00000168481|Vega:OTTHUMG00000131599 +203197 TMEM268 HGNC:HGNC:24513|Ensembl:ENSG00000157693|Vega:OTTHUMG00000020541 +203228 C9orf72 MIM:614260|HGNC:HGNC:28337|Ensembl:ENSG00000147894|Vega:OTTHUMG00000019716 +203238 CCDC171 HGNC:HGNC:29828|Ensembl:ENSG00000164989|Vega:OTTHUMG00000019584 +203245 NAIF1 MIM:610673|HGNC:HGNC:25446|Ensembl:ENSG00000171169|Vega:OTTHUMG00000020727 +203259 FAM219A HGNC:HGNC:19920|Ensembl:ENSG00000164970|Vega:OTTHUMG00000019822 +203260 CCDC107 HGNC:HGNC:28465|Ensembl:ENSG00000159884|Vega:OTTHUMG00000019868 +203274 LINC00537 HGNC:HGNC:43654 +203286 ANKS6 MIM:615370|HGNC:HGNC:26724|Ensembl:ENSG00000165138|Vega:OTTHUMG00000020347 +203328 SUSD3 MIM:616429|HGNC:HGNC:28391|Ensembl:ENSG00000157303|Vega:OTTHUMG00000020241 +203413 CT83 MIM:300625|HGNC:HGNC:33494|Ensembl:ENSG00000204019|Vega:OTTHUMG00000022244 +203414 LINC01560 HGNC:HGNC:27333 +203427 SLC25A43 MIM:300641|HGNC:HGNC:30557|Ensembl:ENSG00000077713|Vega:OTTHUMG00000022272 +203429 FAM226A HGNC:HGNC:28544 +203430 RTL3 HGNC:HGNC:22997|Ensembl:ENSG00000179300|Vega:OTTHUMG00000021892 +203447 NRK MIM:300791|HGNC:HGNC:25391|Ensembl:ENSG00000123572|Vega:OTTHUMG00000022143 +203477 HMGA1P1 HGNC:HGNC:13321 +203510 HMGB3P30 HGNC:HGNC:39333 +203522 INTS6L HGNC:HGNC:27334|Ensembl:ENSG00000165359|Vega:OTTHUMG00000022484 +203523 ZNF449 MIM:300627|HGNC:HGNC:21039|Ensembl:ENSG00000173275|Vega:OTTHUMG00000022478 +203547 VMA21 MIM:300913|HGNC:HGNC:22082|Ensembl:ENSG00000160131|Vega:OTTHUMG00000024168 +203562 TMEM31 HGNC:HGNC:28601|Ensembl:ENSG00000179363|Vega:OTTHUMG00000022109 +203569 PAGE2 MIM:300738|HGNC:HGNC:31804|Ensembl:ENSG00000234068|Vega:OTTHUMG00000021648 +203611 CDY2B HGNC:HGNC:23921|Ensembl:ENSG00000129873|Vega:OTTHUMG00000041652 +203859 ANO5 MIM:608662|HGNC:HGNC:27337|Ensembl:ENSG00000171714|Vega:OTTHUMG00000166051 +203930 LOC203930 - +204010 RPSAP52 HGNC:HGNC:35752|Ensembl:ENSG00000241749 +204219 CERS3 MIM:615276|HGNC:HGNC:23752|Ensembl:ENSG00000154227|Vega:OTTHUMG00000172568 +204474 PDILT HGNC:HGNC:27338|Ensembl:ENSG00000169340|Vega:OTTHUMG00000131487 +204777 IGLJCOR18 HGNC:HGNC:28614|IMGT/GENE-DB:IGLJ-C/OR18 +204800 LOC204800 - +204801 NLRP11 MIM:609664|HGNC:HGNC:22945|Ensembl:ENSG00000179873|Vega:OTTHUMG00000180921 +204851 HIPK1 MIM:608003|HGNC:HGNC:19006|Ensembl:ENSG00000163349|Vega:OTTHUMG00000011983 +204962 SLC44A5 HGNC:HGNC:28524|Ensembl:ENSG00000137968|Vega:OTTHUMG00000009721 +205147 AMER3 HGNC:HGNC:26771|Ensembl:ENSG00000178171|Vega:OTTHUMG00000131637 +205251 LINC00116 HGNC:HGNC:27339 +205272 CNN2P8 HGNC:HGNC:39533 +205327 C2orf69 HGNC:HGNC:26799|Ensembl:ENSG00000178074|Vega:OTTHUMG00000154480 +205428 C3orf58 MIM:612200|HGNC:HGNC:28490|Ensembl:ENSG00000181744|Vega:OTTHUMG00000159380 +205564 SENP5 MIM:612845|HGNC:HGNC:28407|Ensembl:ENSG00000119231|Vega:OTTHUMG00000155527 +205655 NBPF21P HGNC:HGNC:32001 +205717 USF3 MIM:617568|HGNC:HGNC:30494|Ensembl:ENSG00000176542|Vega:OTTHUMG00000159322 +205860 TRIML2 HGNC:HGNC:26378|Ensembl:ENSG00000179046|Vega:OTTHUMG00000160225 +206338 LVRN MIM:610046|HGNC:HGNC:26904|Ensembl:ENSG00000172901|Vega:OTTHUMG00000128890 +206358 SLC36A1 MIM:606561|HGNC:HGNC:18761|Ensembl:ENSG00000123643|Vega:OTTHUMG00000130125 +206412 C6orf163 HGNC:HGNC:21403|Ensembl:ENSG00000203872|Vega:OTTHUMG00000015169 +206426 PIP5K1P1 HGNC:HGNC:28372 +207032 RPL36AP52 - +207063 DHRSX HGNC:HGNC:18399|Ensembl:ENSG00000169084|Vega:OTTHUMG00000021068 +207107 SFTA1P HGNC:HGNC:18383|Ensembl:ENSG00000225383 +207115 LATD MIM:601086 +207147 TRY2P Ensembl:ENSG00000186163 +207148 TRY7 - +219285 SAMD9L MIM:611170|HGNC:HGNC:1349|Ensembl:ENSG00000177409|Vega:OTTHUMG00000155807 +219287 AMER2 MIM:614659|HGNC:HGNC:26360|Ensembl:ENSG00000165566|Vega:OTTHUMG00000016602 +219293 ATAD3C MIM:617227|HGNC:HGNC:32151|Ensembl:ENSG00000215915|Vega:OTTHUMG00000000531 +219333 USP12 HGNC:HGNC:20485|Ensembl:ENSG00000152484|Vega:OTTHUMG00000016626 +219347 TMEM254-AS1 HGNC:HGNC:27340 +219348 PLAC9 MIM:612857|HGNC:HGNC:19255|Ensembl:ENSG00000189129|Vega:OTTHUMG00000018596 +219402 MTIF3 HGNC:HGNC:29788|Ensembl:ENSG00000122033|Vega:OTTHUMG00000016633 +219409 GSX1 MIM:616542|HGNC:HGNC:20374|Ensembl:ENSG00000169840|Vega:OTTHUMG00000016637 +219417 OR8U1 HGNC:HGNC:19611|Ensembl:ENSG00000172199|Vega:OTTHUMG00000166860 +219428 OR4C16 HGNC:HGNC:15172|Ensembl:ENSG00000279514|Vega:OTTHUMG00000165198 +219429 OR4C11 HGNC:HGNC:15167|Ensembl:ENSG00000172188|Vega:OTTHUMG00000165290 +219431 OR4S2 HGNC:HGNC:15183|Ensembl:ENSG00000174982|Vega:OTTHUMG00000166799 +219432 OR4C6 HGNC:HGNC:14743|Ensembl:ENSG00000181903|Vega:OTTHUMG00000166800 +219436 OR5D14 HGNC:HGNC:15281|Ensembl:ENSG00000186113|Vega:OTTHUMG00000166809 +219437 OR5L1 HGNC:HGNC:8350|Ensembl:ENSG00000279395|Vega:OTTHUMG00000166810 +219438 OR5D18 HGNC:HGNC:15285|Ensembl:ENSG00000186119|Vega:OTTHUMG00000166811 +219445 OR7E5P HGNC:HGNC:8435 +219447 OR5AS1 HGNC:HGNC:15261|Ensembl:ENSG00000181785|Vega:OTTHUMG00000166830 +219453 OR8K5 HGNC:HGNC:15315|Ensembl:ENSG00000181752|Vega:OTTHUMG00000166820 +219464 OR5T2 HGNC:HGNC:15296|Ensembl:ENSG00000181718|Vega:OTTHUMG00000166851 +219469 OR8H1 HGNC:HGNC:14824|Ensembl:ENSG00000181693|Vega:OTTHUMG00000162671 +219473 OR8K3 HGNC:HGNC:15313|Ensembl:ENSG00000280314|Vega:OTTHUMG00000166855 +219477 OR8J1 HGNC:HGNC:14855|Ensembl:ENSG00000172487|Vega:OTTHUMG00000166859 +219479 OR5R1 HGNC:HGNC:14841|Ensembl:ENSG00000279961|Vega:OTTHUMG00000154219 +219482 OR5M3 HGNC:HGNC:14806|Ensembl:ENSG00000174937|Vega:OTTHUMG00000166875 +219484 OR5M8 HGNC:HGNC:14846|Ensembl:ENSG00000181371|Vega:OTTHUMG00000166877 +219487 OR5M11 HGNC:HGNC:15291|Ensembl:ENSG00000255223|Vega:OTTHUMG00000166861 +219493 OR5AR1 HGNC:HGNC:15260|Ensembl:ENSG00000172459|Vega:OTTHUMG00000154213 +219525 OR5AK4P HGNC:HGNC:15253|Ensembl:ENSG00000283307 +219527 LRRC55 MIM:615213|HGNC:HGNC:32324|Ensembl:ENSG00000183908|Vega:OTTHUMG00000159309 +219537 SMTNL1 MIM:613664|HGNC:HGNC:32394|Ensembl:ENSG00000214872|Vega:OTTHUMG00000167046 +219539 YPEL4 MIM:609725|HGNC:HGNC:18328|Ensembl:ENSG00000166793|Vega:OTTHUMG00000167138 +219541 MED19 MIM:612385|HGNC:HGNC:29600|Ensembl:ENSG00000156603|Vega:OTTHUMG00000167199 +219557 TEX47 HGNC:HGNC:22402|Ensembl:ENSG00000164645|Vega:OTTHUMG00000153859 +219578 ZNF804B HGNC:HGNC:21958|Ensembl:ENSG00000182348|Vega:OTTHUMG00000131037 +219595 FOLH1B MIM:609020|HGNC:HGNC:13636 +219621 C10orf107 HGNC:HGNC:28678|Ensembl:ENSG00000183346|Vega:OTTHUMG00000018295 +219623 TMEM26 HGNC:HGNC:28550|Ensembl:ENSG00000196932|Vega:OTTHUMG00000018293 +219654 ZCCHC24 HGNC:HGNC:26911|Ensembl:ENSG00000165424|Vega:OTTHUMG00000018561 +219670 ENKUR MIM:611025|HGNC:HGNC:28388|Ensembl:ENSG00000151023|Vega:OTTHUMG00000017827 +219681 ARMC3 MIM:611226|HGNC:HGNC:30964|Ensembl:ENSG00000165309|Vega:OTTHUMG00000017811 +219699 UNC5B MIM:607870|HGNC:HGNC:12568|Ensembl:ENSG00000107731|Vega:OTTHUMG00000018422 +219731 PROSER2-AS1 HGNC:HGNC:27343|Ensembl:ENSG00000225778 +219736 STOX1 MIM:609397|HGNC:HGNC:23508|Ensembl:ENSG00000165730|Vega:OTTHUMG00000018367 +219738 FAM241B HGNC:HGNC:23519|Ensembl:ENSG00000171224|Vega:OTTHUMG00000018383 +219743 TYSND1 MIM:611017|HGNC:HGNC:28531|Ensembl:ENSG00000156521|Vega:OTTHUMG00000018397 +219749 ZNF25 MIM:194528|HGNC:HGNC:13043|Ensembl:ENSG00000175395|Vega:OTTHUMG00000019344 +219752 TACC1P1 HGNC:HGNC:44974 +219770 GJD4 MIM:611922|HGNC:HGNC:23296|Ensembl:ENSG00000177291|Vega:OTTHUMG00000017957 +219771 CCNY MIM:612786|HGNC:HGNC:23354|Ensembl:ENSG00000108100|Vega:OTTHUMG00000017955 +219790 RTKN2 HGNC:HGNC:19364|Ensembl:ENSG00000182010|Vega:OTTHUMG00000018299 +219793 TBATA MIM:612640|HGNC:HGNC:23511|Ensembl:ENSG00000166220|Vega:OTTHUMG00000018413 +219833 C11orf45 HGNC:HGNC:28584|Ensembl:ENSG00000174370|Vega:OTTHUMG00000165796 +219844 HYLS1 MIM:610693|HGNC:HGNC:26558|Ensembl:ENSG00000198331|Vega:OTTHUMG00000165858 +219854 TMEM218 HGNC:HGNC:27344|Ensembl:ENSG00000150433|Vega:OTTHUMG00000165880 +219855 SLC37A2 HGNC:HGNC:20644|Ensembl:ENSG00000134955|Vega:OTTHUMG00000165879 +219858 OR8B12 HGNC:HGNC:15307|Ensembl:ENSG00000170953|Vega:OTTHUMG00000165922 +219865 OR8G5 HGNC:HGNC:19622|Ensembl:ENSG00000255298|Vega:OTTHUMG00000186059 +219869 OR10G8 HGNC:HGNC:14845|Ensembl:ENSG00000234560|Vega:OTTHUMG00000165968 +219870 OR10G9 HGNC:HGNC:15129|Ensembl:ENSG00000236981|Vega:OTTHUMG00000165967 +219873 OR10S1 HGNC:HGNC:14807|Ensembl:ENSG00000196248|Vega:OTTHUMG00000165963 +219874 OR6T1 HGNC:HGNC:14848|Ensembl:ENSG00000181499|Vega:OTTHUMG00000165962 +219875 OR4D5 HGNC:HGNC:14852|Ensembl:ENSG00000171014|Vega:OTTHUMG00000165961 +219899 TBCEL MIM:610451|HGNC:HGNC:28115|Ensembl:ENSG00000154114|Vega:OTTHUMG00000166061 +219902 TMEM136 HGNC:HGNC:28280|Ensembl:ENSG00000181264|Vega:OTTHUMG00000166142 +219927 MRPL21 MIM:611834|HGNC:HGNC:14479|Ensembl:ENSG00000197345|Vega:OTTHUMG00000167893 +219931 TPCN2 MIM:612163|HGNC:HGNC:20820|Ensembl:ENSG00000162341|Vega:OTTHUMG00000167898 +219938 SPATA19 MIM:609805|HGNC:HGNC:30614|Ensembl:ENSG00000166118|Vega:OTTHUMG00000167120 +219952 OR6Q1 HGNC:HGNC:15302|Ensembl:ENSG00000279051|Vega:OTTHUMG00000168831 +219954 OR9I1 HGNC:HGNC:14718|Ensembl:ENSG00000172377|Vega:OTTHUMG00000167404 +219956 OR9Q1 HGNC:HGNC:14724|Ensembl:ENSG00000186509|Vega:OTTHUMG00000167413 +219957 OR9Q2 HGNC:HGNC:15328|Ensembl:ENSG00000186513|Vega:OTTHUMG00000167414 +219958 OR1S2 HGNC:HGNC:15141|Ensembl:ENSG00000197887|Vega:OTTHUMG00000167541 +219959 OR1S1 HGNC:HGNC:8227|Ensembl:ENSG00000280204|Vega:OTTHUMG00000167463 +219960 OR10Q1 HGNC:HGNC:15134|Ensembl:ENSG00000180475|Vega:OTTHUMG00000167542 +219965 OR5B17 HGNC:HGNC:15267|Ensembl:ENSG00000197786|Vega:OTTHUMG00000167465 +219968 OR5B21 HGNC:HGNC:19616|Ensembl:ENSG00000198283|Vega:OTTHUMG00000167519 +219970 GLYATL2 MIM:614762|HGNC:HGNC:24178|Ensembl:ENSG00000156689|Vega:OTTHUMG00000167432 +219972 MPEG1 MIM:610390|HGNC:HGNC:29619|Ensembl:ENSG00000197629|Vega:OTTHUMG00000162676 +219981 OR5A2 HGNC:HGNC:15249|Ensembl:ENSG00000172324|Vega:OTTHUMG00000167419 +219982 OR5A1 HGNC:HGNC:8319|Ensembl:ENSG00000172320|Vega:OTTHUMG00000167339 +219983 OR4D6 HGNC:HGNC:15175|Ensembl:ENSG00000166884|Vega:OTTHUMG00000167340 +219986 OR4D11 HGNC:HGNC:15174|Ensembl:ENSG00000176200|Vega:OTTHUMG00000167342 +219988 PATL1 MIM:614660|HGNC:HGNC:26721|Ensembl:ENSG00000166889|Vega:OTTHUMG00000167423 +219990 OOSP2 HGNC:HGNC:26699|Ensembl:ENSG00000149507|Vega:OTTHUMG00000167379 +219995 MS4A15 HGNC:HGNC:28573|Ensembl:ENSG00000166961|Vega:OTTHUMG00000167688 +220001 VWCE MIM:611115|HGNC:HGNC:26487|Ensembl:ENSG00000167992|Vega:OTTHUMG00000168208 +220002 CYB561A3 HGNC:HGNC:23014|Ensembl:ENSG00000162144|Vega:OTTHUMG00000157187 +220004 PPP1R32 HGNC:HGNC:28869|Ensembl:ENSG00000162148|Vega:OTTHUMG00000168176 +220032 GDPD4 HGNC:HGNC:24849|Ensembl:ENSG00000178795|Vega:OTTHUMG00000165136 +220042 DDIAS HGNC:HGNC:26351|Ensembl:ENSG00000165490|Vega:OTTHUMG00000166929 +220047 CCDC83 HGNC:HGNC:28535|Ensembl:ENSG00000150676|Vega:OTTHUMG00000166978 +220064 ORAOV1 MIM:607224|HGNC:HGNC:17589|Ensembl:ENSG00000149716|Vega:OTTHUMG00000167885 +220070 SHANK2-AS3 HGNC:HGNC:25098|Ensembl:ENSG00000171671 +220074 LRTOMT MIM:612414|HGNC:HGNC:25033|Ensembl:ENSG00000184154|Vega:OTTHUMG00000154887 +220077 LOC220077 - +220081 ERICH6B HGNC:HGNC:26523|Ensembl:ENSG00000165837|Vega:OTTHUMG00000016856 +220082 SPERT HGNC:HGNC:30720|Ensembl:ENSG00000174015|Vega:OTTHUMG00000016861 +220107 DLEU7 HGNC:HGNC:17567|Ensembl:ENSG00000186047|Vega:OTTHUMG00000016936 +220108 FAM124A HGNC:HGNC:26413|Ensembl:ENSG00000150510|Vega:OTTHUMG00000016942 +220112 CTAGE3P MIM:608857|HGNC:HGNC:24348 +220115 TPTE2P3 HGNC:HGNC:27345 +220134 SKA1 MIM:616673|HGNC:HGNC:28109|Ensembl:ENSG00000154839|Vega:OTTHUMG00000132685 +220136 CFAP53 MIM:614759|HGNC:HGNC:26530|Ensembl:ENSG00000172361|Vega:OTTHUMG00000132668 +220147 CTBP2P3 HGNC:HGNC:45195 +220158 GTSCR1 HGNC:HGNC:18406 +220164 DOK6 MIM:611402|HGNC:HGNC:28301|Ensembl:ENSG00000206052|Vega:OTTHUMG00000178688 +220202 ATOH7 MIM:609875|HGNC:HGNC:13907|Ensembl:ENSG00000179774|Vega:OTTHUMG00000018346 +220213 OTUD1 MIM:612022|HGNC:HGNC:27346|Ensembl:ENSG00000165312|Vega:OTTHUMG00000017819 +220296 HEPACAM MIM:611642|HGNC:HGNC:26361|Ensembl:ENSG00000165478|Vega:OTTHUMG00000165938 +220323 OAF HGNC:HGNC:28752|Ensembl:ENSG00000184232|Vega:OTTHUMG00000166139 +220359 TIGD3 HGNC:HGNC:18334|Ensembl:ENSG00000173825|Vega:OTTHUMG00000165986 +220382 FAM181B HGNC:HGNC:28512|Ensembl:ENSG00000182103|Vega:OTTHUMG00000166869 +220388 CCDC89 HGNC:HGNC:26762|Ensembl:ENSG00000179071|Vega:OTTHUMG00000166976 +220416 LRRC63 HGNC:HGNC:34296|Ensembl:ENSG00000173988|Vega:OTTHUMG00000016866 +220429 CTAGE10P HGNC:HGNC:37288|Ensembl:ENSG00000181358 +220433 RPS4XP16 HGNC:HGNC:36365 +220441 RNF152 MIM:616512|HGNC:HGNC:26811|Ensembl:ENSG00000176641|Vega:OTTHUMG00000132774 +220594 USP32P2 HGNC:HGNC:30751|Ensembl:ENSG00000233327 +220717 RPLP0P6 HGNC:HGNC:36404 +220729 LOC220729 Ensembl:ENSG00000214135 +220786 CDK7P1 HGNC:HGNC:18614 +220793 FUNDC2P1 HGNC:HGNC:17253 +220832 FABP5P3 HGNC:HGNC:22573|Ensembl:ENSG00000241735 +220869 CBWD5 HGNC:HGNC:24584|Ensembl:ENSG00000147996|Vega:OTTHUMG00000013336 +220885 RPSAP15 HGNC:HGNC:31464 +220906 WAC-AS1 HGNC:HGNC:27347 +220929 ZNF438 HGNC:HGNC:21029|Ensembl:ENSG00000183621|Vega:OTTHUMG00000017904 +220930 ZEB1-AS1 MIM:616915|HGNC:HGNC:42354 +220959 KRT8P16 HGNC:HGNC:33368 +220963 SLC16A9 MIM:614242|HGNC:HGNC:23520|Ensembl:ENSG00000165449|Vega:OTTHUMG00000018283 +220965 FAM13C HGNC:HGNC:19371|Ensembl:ENSG00000148541|Vega:OTTHUMG00000018277 +220972 MARCH8 MIM:613335|HGNC:HGNC:23356|Ensembl:ENSG00000165406|Vega:OTTHUMG00000019345 +220974 OR6D1P HGNC:HGNC:14849 +220979 C10orf25 HGNC:HGNC:23509 +220980 TMEM72-AS1 HGNC:HGNC:27349|Ensembl:ENSG00000224812 +220988 HNRNPA3 MIM:605372|HGNC:HGNC:24941|Ensembl:ENSG00000170144|Vega:OTTHUMG00000132529 +220992 ZNF485 HGNC:HGNC:23440|Ensembl:ENSG00000198298|Vega:OTTHUMG00000018040 +221002 RASGEF1A MIM:614531|HGNC:HGNC:24246|Ensembl:ENSG00000198915|Vega:OTTHUMG00000018025 +221017 CEP57L1P1 HGNC:HGNC:23521 +221035 REEP3 MIM:609348|HGNC:HGNC:23711|Ensembl:ENSG00000165476|Vega:OTTHUMG00000018318 +221037 JMJD1C MIM:604503|HGNC:HGNC:12313|Ensembl:ENSG00000171988|Vega:OTTHUMG00000018311 +221044 UCMA HGNC:HGNC:25205|Ensembl:ENSG00000165623|Vega:OTTHUMG00000017692 +221060 C10orf111 HGNC:HGNC:28582 +221061 FAM171A1 HGNC:HGNC:23522|Ensembl:ENSG00000148468|Vega:OTTHUMG00000017732 +221074 SLC39A12 MIM:608734|HGNC:HGNC:20860|Ensembl:ENSG00000148482|Vega:OTTHUMG00000017759 +221078 NSUN6 MIM:617199|HGNC:HGNC:23529|Ensembl:ENSG00000241058|Vega:OTTHUMG00000017767 +221079 ARL5B MIM:608909|HGNC:HGNC:23052|Ensembl:ENSG00000165997|Vega:OTTHUMG00000017765 +221091 LRRN4CL HGNC:HGNC:33724|Ensembl:ENSG00000177363|Vega:OTTHUMG00000167581 +221092 HNRNPUL2 HGNC:HGNC:25451|Ensembl:ENSG00000214753|Vega:OTTHUMG00000167773 +221120 ALKBH3 MIM:610603|HGNC:HGNC:30141|Ensembl:ENSG00000166199|Vega:OTTHUMG00000166417 +221122 LOC221122 Ensembl:ENSG00000254654 +221143 EEF1AKMT1 HGNC:HGNC:27351|Ensembl:ENSG00000150456|Vega:OTTHUMG00000016519 +221150 SKA3 HGNC:HGNC:20262|Ensembl:ENSG00000165480|Vega:OTTHUMG00000016539 +221154 MICU2 MIM:610632|HGNC:HGNC:31830|Ensembl:ENSG00000165487|Vega:OTTHUMG00000067414 +221178 SPATA13 MIM:613324|HGNC:HGNC:23222|Ensembl:ENSG00000182957|Ensembl:ENSG00000228741|Ensembl:ENSG00000273167|Vega:OTTHUMG00000016578|Vega:OTTHUMG00000186016 +221180 CYCSP33 HGNC:HGNC:24407 +221184 CPNE2 MIM:604206|HGNC:HGNC:2315|Ensembl:ENSG00000140848|Vega:OTTHUMG00000133471 +221188 ADGRG5 MIM:616965|HGNC:HGNC:19010|Ensembl:ENSG00000159618|Vega:OTTHUMG00000133461 +221191 PRSS54 HGNC:HGNC:26336|Ensembl:ENSG00000103023|Vega:OTTHUMG00000173231 +221223 CES5A HGNC:HGNC:26459|Ensembl:ENSG00000159398|Vega:OTTHUMG00000133236 +221241 LINC00305 MIM:617489|HGNC:HGNC:28597|Ensembl:ENSG00000179676 +221262 CCDC162P HGNC:HGNC:21565|Ensembl:ENSG00000203799 +221264 AK9 MIM:615358|HGNC:HGNC:33814|Ensembl:ENSG00000155085|Vega:OTTHUMG00000157658 +221294 NT5DC1 HGNC:HGNC:21556|Ensembl:ENSG00000178425|Vega:OTTHUMG00000015428 +221301 FAM26D HGNC:HGNC:21094|Ensembl:ENSG00000164451|Vega:OTTHUMG00000015443 +221302 ZUFSP HGNC:HGNC:21224|Ensembl:ENSG00000153975|Vega:OTTHUMG00000015445 +221303 FAM162B HGNC:HGNC:21549|Ensembl:ENSG00000183807|Vega:OTTHUMG00000015446 +221322 TBC1D32 MIM:615867|HGNC:HGNC:21485|Ensembl:ENSG00000146350|Vega:OTTHUMG00000015474 +221336 BEND6 HGNC:HGNC:20871|Ensembl:ENSG00000151917|Vega:OTTHUMG00000014914 +221357 GSTA5 MIM:607605|HGNC:HGNC:19662|Ensembl:ENSG00000182793|Vega:OTTHUMG00000014857 +221391 OPN5 MIM:609042|HGNC:HGNC:19992|Ensembl:ENSG00000124818|Vega:OTTHUMG00000014803 +221393 ADGRF4 MIM:614268|HGNC:HGNC:19011|Ensembl:ENSG00000153294|Vega:OTTHUMG00000014800 +221395 ADGRF5 HGNC:HGNC:19030|Ensembl:ENSG00000069122|Vega:OTTHUMG00000014793 +221400 TDRD6 MIM:611200|HGNC:HGNC:21339|Ensembl:ENSG00000180113|Vega:OTTHUMG00000014788 +221409 SPATS1 HGNC:HGNC:22957|Ensembl:ENSG00000249481|Vega:OTTHUMG00000014764 +221416 C6orf223 HGNC:HGNC:28692|Ensembl:ENSG00000181577|Vega:OTTHUMG00000014753 +221421 RSPH9 MIM:612648|HGNC:HGNC:21057|Ensembl:ENSG00000172426|Vega:OTTHUMG00000014746 +221424 LRRC73 HGNC:HGNC:21375|Ensembl:ENSG00000204052|Vega:OTTHUMG00000014737 +221438 TREML5P HGNC:HGNC:30808 +221442 ADCY10P1 HGNC:HGNC:44143|Ensembl:ENSG00000161912 +221443 OARD1 MIM:614393|HGNC:HGNC:21257|Ensembl:ENSG00000124596|Vega:OTTHUMG00000014667 +221458 KIF6 MIM:613919|HGNC:HGNC:21202|Ensembl:ENSG00000164627|Vega:OTTHUMG00000014648 +221468 TMEM217 HGNC:HGNC:21238|Ensembl:ENSG00000172738|Vega:OTTHUMG00000014618 +221472 FGD2 MIM:605091|HGNC:HGNC:3664|Ensembl:ENSG00000146192|Vega:OTTHUMG00000014616 +221476 PI16 HGNC:HGNC:21245|Ensembl:ENSG00000164530|Vega:OTTHUMG00000014611 +221477 C6orf89 MIM:616642|HGNC:HGNC:21114|Ensembl:ENSG00000198663|Vega:OTTHUMG00000014613 +221481 ARMC12 HGNC:HGNC:21099|Ensembl:ENSG00000157343|Vega:OTTHUMG00000014577 +221491 SMIM29 MIM:611419|HGNC:HGNC:1340|Ensembl:ENSG00000186577 +221496 LEMD2 MIM:616312|HGNC:HGNC:21244|Ensembl:ENSG00000161904|Vega:OTTHUMG00000014535 +221504 ZBTB9 HGNC:HGNC:28323|Ensembl:ENSG00000213588|Vega:OTTHUMG00000140180 +221527 ZBTB12 HGNC:HGNC:19066|Ensembl:ENSG00000204366|Vega:OTTHUMG00000031169 +221545 C6orf136 HGNC:HGNC:21301|Ensembl:ENSG00000204564|Vega:OTTHUMG00000031221 +221547 RANP1 HGNC:HGNC:21631 +221584 ZSCAN12P1 HGNC:HGNC:13850 +221613 HIST1H2AA MIM:613499|HGNC:HGNC:18729|Ensembl:ENSG00000164508|Vega:OTTHUMG00000014407 +221656 KDM1B MIM:613081|HGNC:HGNC:21577|Ensembl:ENSG00000165097|Vega:OTTHUMG00000014316 +221662 RBM24 HGNC:HGNC:21539|Ensembl:ENSG00000112183|Vega:OTTHUMG00000014306 +221687 RNF182 HGNC:HGNC:28522|Ensembl:ENSG00000180537|Vega:OTTHUMG00000014280 +221692 PHACTR1 MIM:608723|HGNC:HGNC:20990|Ensembl:ENSG00000112137|Vega:OTTHUMG00000014270 +221710 SMIM13 HGNC:HGNC:27356|Ensembl:ENSG00000224531|Vega:OTTHUMG00000014253 +221711 SYCP2L MIM:616799|HGNC:HGNC:21537|Ensembl:ENSG00000153157|Vega:OTTHUMG00000014250 +221717 MRPL48P1 HGNC:HGNC:21379 +221718 LINC00518 HGNC:HGNC:28626 +221749 PXDC1 HGNC:HGNC:21361|Ensembl:ENSG00000168994|Vega:OTTHUMG00000014146 +221756 SERPINB9P1 HGNC:HGNC:28590 +221785 ZSCAN25 HGNC:HGNC:21961|Ensembl:ENSG00000197037|Vega:OTTHUMG00000074055 +221786 FAM200A HGNC:HGNC:25401|Ensembl:ENSG00000221909|Vega:OTTHUMG00000156723 +221806 VWDE HGNC:HGNC:21897|Ensembl:ENSG00000146530|Vega:OTTHUMG00000152315 +221823 PRPS1L1 MIM:611566|HGNC:HGNC:9463|Ensembl:ENSG00000229937|Vega:OTTHUMG00000152742 +221830 TWISTNB MIM:608312|HGNC:HGNC:18027|Ensembl:ENSG00000105849|Vega:OTTHUMG00000152497 +221833 SP8 MIM:608306|HGNC:HGNC:19196|Ensembl:ENSG00000164651|Vega:OTTHUMG00000094788 +221838 EEF1A1P6 HGNC:HGNC:3201 +221883 HOXA11-AS MIM:607530|HGNC:HGNC:24957|Ensembl:ENSG00000240990 +221895 JAZF1 MIM:606246|HGNC:HGNC:28917|Ensembl:ENSG00000153814|Vega:OTTHUMG00000128545 +221908 PPP1R35 HGNC:HGNC:28320|Ensembl:ENSG00000160813|Vega:OTTHUMG00000159540 +221914 GPC2 HGNC:HGNC:4450|Ensembl:ENSG00000213420|Vega:OTTHUMG00000154894 +221927 BRAT1 MIM:614506|HGNC:HGNC:21701|Ensembl:ENSG00000106009|Vega:OTTHUMG00000119091 +221935 SDK1 MIM:607216|HGNC:HGNC:19307|Ensembl:ENSG00000146555|Vega:OTTHUMG00000151733 +221937 FOXK1 MIM:616302|HGNC:HGNC:23480|Ensembl:ENSG00000164916|Vega:OTTHUMG00000151739 +221938 MMD2 MIM:614581|HGNC:HGNC:30133|Ensembl:ENSG00000136297|Vega:OTTHUMG00000151844 +221946 LOC221946 - +221955 DAGLB MIM:614016|HGNC:HGNC:28923|Ensembl:ENSG00000164535|Vega:OTTHUMG00000125513 +221960 CCZ1B HGNC:HGNC:21717|Ensembl:ENSG00000146574|Vega:OTTHUMG00000152441 +221981 THSD7A MIM:612249|HGNC:HGNC:22207|Ensembl:ENSG00000005108|Vega:OTTHUMG00000152346 +222005 SLC25A5P3 HGNC:HGNC:507 +222008 VSTM2A HGNC:HGNC:28499|Ensembl:ENSG00000170419|Vega:OTTHUMG00000129271 +222029 DKFZp434L192 - +222052 TTC4P1 HGNC:HGNC:12395 +222068 TMED4 MIM:612038|HGNC:HGNC:22301|Ensembl:ENSG00000158604|Vega:OTTHUMG00000129210 +222161 DKFZP586I1420 - +222166 MTURN HGNC:HGNC:25457|Ensembl:ENSG00000180354|Vega:OTTHUMG00000128559 +222171 PRR15 HGNC:HGNC:22310|Ensembl:ENSG00000176532|Vega:OTTHUMG00000128555 +222183 SRRM3 HGNC:HGNC:26729|Ensembl:ENSG00000177679|Vega:OTTHUMG00000130489 +222194 RSBN1L HGNC:HGNC:24765|Ensembl:ENSG00000187257|Vega:OTTHUMG00000155517 +222223 KIAA1324L MIM:614048|HGNC:HGNC:21945|Ensembl:ENSG00000164659|Vega:OTTHUMG00000153995 +222229 LRWD1 MIM:615167|HGNC:HGNC:21769|Ensembl:ENSG00000161036|Vega:OTTHUMG00000157718 +222234 FAM185A HGNC:HGNC:22412|Ensembl:ENSG00000222011|Vega:OTTHUMG00000154140 +222235 FBXL13 MIM:609080|HGNC:HGNC:21658|Ensembl:ENSG00000161040|Vega:OTTHUMG00000157224 +222236 NAPEPLD MIM:612334|HGNC:HGNC:21683|Ensembl:ENSG00000161048|Vega:OTTHUMG00000157204 +222255 ATXN7L1 HGNC:HGNC:22210|Ensembl:ENSG00000146776|Vega:OTTHUMG00000157521 +222256 CDHR3 MIM:615610|HGNC:HGNC:26308|Ensembl:ENSG00000128536|Vega:OTTHUMG00000157520 +222389 BEND7 HGNC:HGNC:23514|Ensembl:ENSG00000165626|Vega:OTTHUMG00000017699 +222484 LNX2 MIM:609733|HGNC:HGNC:20421|Ensembl:ENSG00000139517|Vega:OTTHUMG00000016634 +222487 ADGRG3 HGNC:HGNC:13728|Ensembl:ENSG00000182885|Vega:OTTHUMG00000133458 +222537 HS3ST5 MIM:609407|HGNC:HGNC:19419|Ensembl:ENSG00000249853|Vega:OTTHUMG00000015412 +222545 GPRC6A MIM:613572|HGNC:HGNC:18510|Ensembl:ENSG00000173612|Vega:OTTHUMG00000015447 +222546 RFX6 MIM:612659|HGNC:HGNC:21478|Ensembl:ENSG00000185002|Vega:OTTHUMG00000015449 +222553 SLC35F1 HGNC:HGNC:21483|Ensembl:ENSG00000196376|Vega:OTTHUMG00000015460 +222584 FAM83B HGNC:HGNC:21357|Ensembl:ENSG00000168143|Vega:OTTHUMG00000014899 +222611 ADGRF2 HGNC:HGNC:18991|Ensembl:ENSG00000164393|Vega:OTTHUMG00000046168 +222642 TSPO2 HGNC:HGNC:21256|Ensembl:ENSG00000112212|Vega:OTTHUMG00000014666 +222643 UNC5CL MIM:617464|HGNC:HGNC:21203|Ensembl:ENSG00000124602|Vega:OTTHUMG00000014665 +222658 KCTD20 MIM:615932|HGNC:HGNC:21052|Ensembl:ENSG00000112078|Vega:OTTHUMG00000014597 +222659 PXT1 HGNC:HGNC:18312|Ensembl:ENSG00000179165|Vega:OTTHUMG00000159815 +222662 LHFPL5 MIM:609427|HGNC:HGNC:21253|Ensembl:ENSG00000197753|Vega:OTTHUMG00000014584 +222663 SCUBE3 MIM:614708|HGNC:HGNC:13655|Ensembl:ENSG00000146197|Vega:OTTHUMG00000014562 +222696 ZSCAN23 HGNC:HGNC:21193|Ensembl:ENSG00000187987|Vega:OTTHUMG00000016346 +222698 NKAPL HGNC:HGNC:21584|Ensembl:ENSG00000189134|Vega:OTTHUMG00000014517 +222699 TOB2P1 HGNC:HGNC:13986 +222701 ZNF192P2 HGNC:HGNC:42862 +222826 FAM217A HGNC:HGNC:21362|Ensembl:ENSG00000145975|Vega:OTTHUMG00000014159 +222865 TMEM130 HGNC:HGNC:25429|Ensembl:ENSG00000166448|Vega:OTTHUMG00000154419 +222894 FERD3L HGNC:HGNC:16660|Ensembl:ENSG00000146618|Vega:OTTHUMG00000090823 +222901 RPL23P8 HGNC:HGNC:36225|Ensembl:ENSG00000219451 +222950 NYAP1 MIM:615477|HGNC:HGNC:22009|Ensembl:ENSG00000166924|Vega:OTTHUMG00000155290 +222962 SLC29A4 MIM:609149|HGNC:HGNC:23097|Ensembl:ENSG00000164638|Vega:OTTHUMG00000023797 +222967 RSPH10B HGNC:HGNC:27362|Ensembl:ENSG00000155026|Vega:OTTHUMG00000152378 +223075 CCDC129 HGNC:HGNC:27363|Ensembl:ENSG00000180347|Vega:OTTHUMG00000128611 +223082 ZNRF2 MIM:612061|HGNC:HGNC:22316|Ensembl:ENSG00000180233|Vega:OTTHUMG00000097759 +223117 SEMA3D MIM:609907|HGNC:HGNC:10726|Ensembl:ENSG00000153993|Vega:OTTHUMG00000154569 +225689 MAPK15 HGNC:HGNC:24667|Ensembl:ENSG00000181085|Vega:OTTHUMG00000146450 +245711 SPDYA MIM:614029|HGNC:HGNC:30613|Ensembl:ENSG00000163806|Vega:OTTHUMG00000074041 +245802 MS4A6E MIM:608402|HGNC:HGNC:14285|Ensembl:ENSG00000166926|Vega:OTTHUMG00000167355 +245806 VGLL2 MIM:609979|HGNC:HGNC:20232|Ensembl:ENSG00000170162|Vega:OTTHUMG00000015451 +245812 CNPY4 MIM:610047|HGNC:HGNC:28631|Ensembl:ENSG00000166997|Vega:OTTHUMG00000154817 +245821 DFNB34 HGNC:HGNC:17143 +245908 DEFB105A HGNC:HGNC:18087|Ensembl:ENSG00000186562|Vega:OTTHUMG00000150011 +245909 DEFB106A HGNC:HGNC:18088|Ensembl:ENSG00000186579|Vega:OTTHUMG00000150012 +245910 DEFB107A HGNC:HGNC:18086|Ensembl:ENSG00000186572|Vega:OTTHUMG00000150013 +245911 DEFB108B HGNC:HGNC:29966|Ensembl:ENSG00000184276|Vega:OTTHUMG00000167533 +245912 DEFB109A HGNC:HGNC:18090 +245913 DEFB110 HGNC:HGNC:18091|Ensembl:ENSG00000203970|Vega:OTTHUMG00000160208 +245915 DEFB112 HGNC:HGNC:18093|Ensembl:ENSG00000180872|Vega:OTTHUMG00000160215 +245927 DEFB113 HGNC:HGNC:18094|Ensembl:ENSG00000214642|Vega:OTTHUMG00000160210 +245928 DEFB114 MIM:615243|HGNC:HGNC:18095|Ensembl:ENSG00000177684|Vega:OTTHUMG00000160209 +245929 DEFB115 HGNC:HGNC:18096|Ensembl:ENSG00000215547|Vega:OTTHUMG00000159284 +245930 DEFB116 HGNC:HGNC:18097|Ensembl:ENSG00000215545|Vega:OTTHUMG00000159285 +245931 DEFB117 HGNC:HGNC:18098 +245932 DEFB119 MIM:615997|HGNC:HGNC:18099|Ensembl:ENSG00000180483|Vega:OTTHUMG00000032172 +245934 DEFB121 MIM:616075|HGNC:HGNC:18101|Ensembl:ENSG00000204548|Vega:OTTHUMG00000032171 +245935 DEFB122 MIM:616077|HGNC:HGNC:18102|Ensembl:ENSG00000204547 +245936 DEFB123 MIM:616076|HGNC:HGNC:18103|Ensembl:ENSG00000180424|Vega:OTTHUMG00000032170 +245937 DEFB124 HGNC:HGNC:18104|Ensembl:ENSG00000180383|Vega:OTTHUMG00000159287 +245938 DEFB125 HGNC:HGNC:18105|Ensembl:ENSG00000178591|Vega:OTTHUMG00000031614 +245939 DEFB128 HGNC:HGNC:18106|Ensembl:ENSG00000185982|Vega:OTTHUMG00000043057 +245940 DEFB130A HGNC:HGNC:18107|Ensembl:ENSG00000232948|Vega:OTTHUMG00000158742 +245972 ATP6V0D2 HGNC:HGNC:18266|Ensembl:ENSG00000147614|Vega:OTTHUMG00000163637 +245973 ATP6V1C2 HGNC:HGNC:18264|Ensembl:ENSG00000143882|Vega:OTTHUMG00000090459 +246100 CTAG1A MIM:300657|HGNC:HGNC:24198|Ensembl:ENSG00000268651|Vega:OTTHUMG00000024238 +246112 TAF13P1 HGNC:HGNC:18699 +246119 TTTY10 HGNC:HGNC:18491|Ensembl:ENSG00000229236 +246122 TTTY7 HGNC:HGNC:18488|Ensembl:ENSG00000147753 +246123 ZNF736P3Y HGNC:HGNC:37728 +246126 TXLNGY MIM:400031|HGNC:HGNC:18473|Ensembl:ENSG00000131002 +246132 HCHOLA4 HGNC:HGNC:18573 +246135 TAF9BP1 HGNC:HGNC:30687 +246175 CNOT6L HGNC:HGNC:18042|Ensembl:ENSG00000138767|Vega:OTTHUMG00000160832 +246176 GAS2L2 MIM:611398|HGNC:HGNC:24846|Ensembl:ENSG00000270765|Vega:OTTHUMG00000188386 +246181 AKR7L MIM:608478|HGNC:HGNC:24056|Ensembl:ENSG00000211454|Vega:OTTHUMG00000002520 +246182 AKR7A2P1 HGNC:HGNC:24062 +246184 CDC26 MIM:614533|HGNC:HGNC:17839|Ensembl:ENSG00000176386|Vega:OTTHUMG00000020521 +246210 IKBKGP1 HGNC:HGNC:24455 +246213 SLC17A8 MIM:607557|HGNC:HGNC:20151|Ensembl:ENSG00000179520|Vega:OTTHUMG00000170358 +246230 CMAL MIM:163000 +246243 RNASEH1 MIM:604123|HGNC:HGNC:18466|Ensembl:ENSG00000171865|Vega:OTTHUMG00000090279 +246259 BMND3 MIM:606928 +246260 BDA1B MIM:607004 +246269 AFG1L MIM:617469|HGNC:HGNC:16411|Ensembl:ENSG00000135537|Vega:OTTHUMG00000015324 +246283 TRBV22OR9-2 HGNC:HGNC:18740|IMGT/GENE-DB:TRBV22/OR9-2 +246285 TRBV26OR9-2 HGNC:HGNC:15485|IMGT/GENE-DB:TRBV26/OR9-2 +246286 TRBVAOR9-2 HGNC:HGNC:18741|IMGT/GENE-DB:TRBVA/OR9-2 +246287 DFNA45 HGNC:HGNC:18691 +246288 DFNA46 HGNC:HGNC:18692 +246289 DFNA47 MIM:608652|HGNC:HGNC:18693 +246312 C21orf91-OT1 HGNC:HGNC:16729|Ensembl:ENSG00000240770 +246319 VAMAS6 MIM:193200 +246321 HSCR6 MIM:606874 +246322 HSCR7 MIM:606875 +246329 STAC3 MIM:615521|HGNC:HGNC:28423|Ensembl:ENSG00000185482|Vega:OTTHUMG00000171271 +246330 PELI3 MIM:609827|HGNC:HGNC:30010|Ensembl:ENSG00000174516|Vega:OTTHUMG00000167109 +246704 LINC00315 HGNC:HGNC:16621 +246705 LINC00314 HGNC:HGNC:16622|Ensembl:ENSG00000178457 +246714 CKS1BP2 HGNC:HGNC:24232 +246715 CKS1BP3 HGNC:HGNC:24233 +246716 YWHAQP2 HGNC:HGNC:23211 +246717 ELOBP1 HGNC:HGNC:39719 +246719 UBE2SP1 HGNC:HGNC:30864 +246720 DYNLL1P1 HGNC:HGNC:20723 +246721 POLR2J2 MIM:609881|HGNC:HGNC:23208|Ensembl:ENSG00000228049|Ensembl:ENSG00000267645|Vega:OTTHUMG00000150388|Vega:OTTHUMG00000180801 +246723 ATP5HP4 HGNC:HGNC:49626 +246731 PPIHP1 HGNC:HGNC:31355 +246734 NPCDR1 HGNC:HGNC:13392 +246737 YWHAZP4 HGNC:HGNC:30851 +246744 STH MIM:607067|HGNC:HGNC:18839|Ensembl:ENSG00000256762|Vega:OTTHUMG00000168633 +246750 MYAS1 MIM:607085 +246751 SMAR MIM:607088 +246754 MTVR2 - +246777 SPESP1 MIM:609399|HGNC:HGNC:15570|Ensembl:ENSG00000258484|Vega:OTTHUMG00000133321 +246778 IL27 MIM:608273|HGNC:HGNC:19157|Ensembl:ENSG00000197272|Vega:OTTHUMG00000097023 +246784 LOC246784 - +246785 OLA1P1 HGNC:HGNC:45274 +252839 TMEM9 MIM:616877|HGNC:HGNC:18823|Ensembl:ENSG00000116857|Vega:OTTHUMG00000035831 +252840 SRP68P2 HGNC:HGNC:30426 +252841 SRP68P1 HGNC:HGNC:30427 +252842 AAT1 MIM:607086 +252843 AAT2 MIM:607087 +252884 ZNF396 MIM:609600|HGNC:HGNC:18824|Ensembl:ENSG00000186496|Vega:OTTHUMG00000132562 +252946 FAM197Y2 HGNC:HGNC:18848|Ensembl:ENSG00000234803 +252948 TTTY16 HGNC:HGNC:18840|Ensembl:ENSG00000225520 +252949 TTTY17A MIM:400040|HGNC:HGNC:18841|Ensembl:ENSG00000228240 +252950 TTTY18 HGNC:HGNC:18842|Ensembl:ENSG00000233699 +252951 TTTY20 HGNC:HGNC:18844|Ensembl:ENSG00000232808 +252952 TTTY19 HGNC:HGNC:18843|Ensembl:ENSG00000232419 +252953 TTTY21 HGNC:HGNC:18845|Ensembl:ENSG00000228890 +252954 TTTY22 HGNC:HGNC:18846|Ensembl:ENSG00000224075 +252955 TTTY23 HGNC:HGNC:18847|Ensembl:ENSG00000239225 +252956 TPM3P1 HGNC:HGNC:16350 +252968 TNPO1P2 HGNC:HGNC:45121 +252969 NEIL2 MIM:608933|HGNC:HGNC:18956|Ensembl:ENSG00000154328|Vega:OTTHUMG00000090753 +252983 STXBP4 MIM:610415|HGNC:HGNC:19694|Ensembl:ENSG00000166263|Vega:OTTHUMG00000074043 +252995 FNDC5 MIM:611906|HGNC:HGNC:20240|Ensembl:ENSG00000160097|Vega:OTTHUMG00000004015 +253012 HEPACAM2 MIM:614133|HGNC:HGNC:27364|Ensembl:ENSG00000188175|Vega:OTTHUMG00000131732 +253013 RPL31P8 HGNC:HGNC:31324 +253017 TECRL MIM:617242|HGNC:HGNC:27365|Ensembl:ENSG00000205678|Vega:OTTHUMG00000160680 +253018 HCG27 HGNC:HGNC:27366|Ensembl:ENSG00000206344|Vega:OTTHUMG00000031248 +253039 PSMD5-AS1 HGNC:HGNC:27367|Ensembl:ENSG00000226752 +253044 LINGO1-AS1 HGNC:HGNC:27368|Ensembl:ENSG00000259666 +253128 LINC00612 HGNC:HGNC:28621|Ensembl:ENSG00000214851 +253143 PRR14L HGNC:HGNC:28738|Ensembl:ENSG00000183530|Vega:OTTHUMG00000030139 +253152 EPHX4 MIM:617401|HGNC:HGNC:23758|Ensembl:ENSG00000172031|Vega:OTTHUMG00000010114 +253175 CDY1B HGNC:HGNC:23920|Ensembl:ENSG00000172352|Vega:OTTHUMG00000045037 +253190 SERHL2 HGNC:HGNC:29446|Ensembl:ENSG00000183569|Vega:OTTHUMG00000150892 +253260 RICTOR MIM:609022|HGNC:HGNC:28611|Ensembl:ENSG00000164327|Vega:OTTHUMG00000162037 +253264 ZNF503-AS1 HGNC:HGNC:27370|Ensembl:ENSG00000226051 +253272 PCGF7P HGNC:HGNC:30341 +253314 EIF4E1B HGNC:HGNC:33179|Ensembl:ENSG00000175766|Vega:OTTHUMG00000163227 +253430 IPMK MIM:609851|HGNC:HGNC:20739|Ensembl:ENSG00000151151|Vega:OTTHUMG00000018268 +253461 ZBTB38 MIM:612218|HGNC:HGNC:26636|Ensembl:ENSG00000177311|Vega:OTTHUMG00000160128 +253512 SLC25A30 MIM:610793|HGNC:HGNC:27371|Ensembl:ENSG00000174032|Vega:OTTHUMG00000016853 +253558 LCLAT1 MIM:614241|HGNC:HGNC:26756|Ensembl:ENSG00000172954|Vega:OTTHUMG00000099349 +253559 CADM2 MIM:609938|HGNC:HGNC:29849|Ensembl:ENSG00000175161|Vega:OTTHUMG00000158990 +253573 LINC02052 HGNC:HGNC:27372|Ensembl:ENSG00000224406 +253582 TMEM244 HGNC:HGNC:21571|Ensembl:ENSG00000203756|Vega:OTTHUMG00000015553 +253635 GPATCH11 HGNC:HGNC:26768|Ensembl:ENSG00000152133|Vega:OTTHUMG00000128469 +253639 ZNF620 HGNC:HGNC:28742|Ensembl:ENSG00000177842|Vega:OTTHUMG00000156044 +253650 ANKRD18A HGNC:HGNC:23643|Ensembl:ENSG00000180071|Vega:OTTHUMG00000186349 +253665 ELOBP2 HGNC:HGNC:39720 +253714 MMS22L MIM:615614|HGNC:HGNC:21475|Ensembl:ENSG00000146263|Vega:OTTHUMG00000015248 +253724 TTC41P HGNC:HGNC:49210|Ensembl:ENSG00000214198 +253725 WASHC2C MIM:613631|HGNC:HGNC:23414|Ensembl:ENSG00000172661|Vega:OTTHUMG00000018089 +253738 EBF3 MIM:607407|HGNC:HGNC:19087|Ensembl:ENSG00000108001|Vega:OTTHUMG00000019265 +253769 WDR27 HGNC:HGNC:21248|Ensembl:ENSG00000184465|Vega:OTTHUMG00000016061 +253782 CERS6 MIM:615336|HGNC:HGNC:23826|Ensembl:ENSG00000172292|Vega:OTTHUMG00000132183 +253827 MSRB3 MIM:613719|HGNC:HGNC:27375|Ensembl:ENSG00000174099|Vega:OTTHUMG00000168866 +253832 ZDHHC20 HGNC:HGNC:20749|Ensembl:ENSG00000180776|Vega:OTTHUMG00000017410 +253868 C20orf166-AS1 HGNC:HGNC:26393 +253933 OR7E39P HGNC:HGNC:8412 +253935 ANGPTL5 MIM:607666|HGNC:HGNC:19705|Ensembl:ENSG00000187151|Vega:OTTHUMG00000167318 +253943 YTHDF3 HGNC:HGNC:26465|Ensembl:ENSG00000185728|Vega:OTTHUMG00000164369 +253959 RALGAPA1 MIM:608884|HGNC:HGNC:17770|Ensembl:ENSG00000174373|Vega:OTTHUMG00000170619 +253962 CACNA1G-AS1 HGNC:HGNC:27377|Ensembl:ENSG00000250107 +253970 SFTA3 HGNC:HGNC:18387|Ensembl:ENSG00000229415|Vega:OTTHUMG00000170540 +253980 KCTD13 MIM:608947|HGNC:HGNC:22234|Ensembl:ENSG00000174943|Vega:OTTHUMG00000132120 +253982 ASPHD1 HGNC:HGNC:27380|Ensembl:ENSG00000174939|Vega:OTTHUMG00000132121 +253986 RPL10AP2 HGNC:HGNC:31081 +254013 ETFBKMT MIM:615256|HGNC:HGNC:28739|Ensembl:ENSG00000139160|Vega:OTTHUMG00000169085 +254028 LOC254028 Ensembl:ENSG00000258573 +254042 METAP1D MIM:610267|HGNC:HGNC:32583|Ensembl:ENSG00000172878|Vega:OTTHUMG00000132283 +254048 UBN2 MIM:613841|HGNC:HGNC:21931|Ensembl:ENSG00000157741|Vega:OTTHUMG00000157623 +254050 LRRC43 HGNC:HGNC:28562|Ensembl:ENSG00000158113|Vega:OTTHUMG00000168915 +254065 BRWD3 MIM:300553|HGNC:HGNC:17342|Ensembl:ENSG00000165288|Vega:OTTHUMG00000021908 +254099 LINC01342 HGNC:HGNC:50551|Ensembl:ENSG00000223823 +254100 SSSCA1-AS1 HGNC:HGNC:27384 +254102 EHBP1L1 HGNC:HGNC:30682|Ensembl:ENSG00000173442|Vega:OTTHUMG00000166520 +254122 SNX32 HGNC:HGNC:26423|Ensembl:ENSG00000172803|Vega:OTTHUMG00000128491 +254128 NIFK-AS1 HGNC:HGNC:27385|Ensembl:ENSG00000236859 +254158 CXorf58 HGNC:HGNC:26356|Ensembl:ENSG00000165182|Vega:OTTHUMG00000021258 +254170 FBXO33 MIM:609103|HGNC:HGNC:19833|Ensembl:ENSG00000165355|Vega:OTTHUMG00000140257 +254173 TTLL10 HGNC:HGNC:26693|Ensembl:ENSG00000162571|Vega:OTTHUMG00000000851 +254187 TSGA10IP HGNC:HGNC:26555|Ensembl:ENSG00000175513|Vega:OTTHUMG00000166753 +254225 RNF169 HGNC:HGNC:26961|Ensembl:ENSG00000166439|Vega:OTTHUMG00000165516 +254228 FAM26E HGNC:HGNC:21568|Ensembl:ENSG00000178033|Vega:OTTHUMG00000015442 +254240 BPIFC MIM:614109|HGNC:HGNC:16503|Ensembl:ENSG00000184459|Vega:OTTHUMG00000058273 +254251 LCORL MIM:611799|HGNC:HGNC:30776|Ensembl:ENSG00000178177|Vega:OTTHUMG00000128538 +254263 CNIH2 MIM:611288|HGNC:HGNC:28744|Ensembl:ENSG00000174871|Vega:OTTHUMG00000166919 +254268 AKNAD1 HGNC:HGNC:28398|Ensembl:ENSG00000162641|Vega:OTTHUMG00000011231 +254272 TBC1D28 HGNC:HGNC:26858|Ensembl:ENSG00000189375|Vega:OTTHUMG00000059054 +254295 PHYHD1 HGNC:HGNC:23396|Ensembl:ENSG00000175287|Vega:OTTHUMG00000020764 +254312 LINC00710 HGNC:HGNC:27386|Ensembl:ENSG00000229240 +254359 ZDHHC24 HGNC:HGNC:27387|Ensembl:ENSG00000174165|Vega:OTTHUMG00000167096 +254394 MCM9 MIM:610098|HGNC:HGNC:21484|Ensembl:ENSG00000111877|Vega:OTTHUMG00000015468 +254398 ARHGAP42P4 HGNC:HGNC:43941 +254427 PROSER2 HGNC:HGNC:23728|Ensembl:ENSG00000148426|Vega:OTTHUMG00000017673 +254428 SLC41A1 MIM:610801|HGNC:HGNC:19429|Ensembl:ENSG00000133065|Vega:OTTHUMG00000036000 +254439 C11orf86 HGNC:HGNC:34442|Ensembl:ENSG00000173237|Vega:OTTHUMG00000153671 +254528 MEIOB HGNC:HGNC:28569|Ensembl:ENSG00000162039|Vega:OTTHUMG00000128683 +254531 LPCAT4 MIM:612039|HGNC:HGNC:30059|Ensembl:ENSG00000176454|Vega:OTTHUMG00000172349 +254552 NUDT8 HGNC:HGNC:8055|Ensembl:ENSG00000167799|Vega:OTTHUMG00000167292 +254559 MIR9-3HG HGNC:HGNC:27388|Ensembl:ENSG00000255571 +254664 MAPK6PS2 HGNC:HGNC:16756 +254700 USP12PX HGNC:HGNC:21410 +254773 LYG2 MIM:616547|HGNC:HGNC:29615|Ensembl:ENSG00000185674|Vega:OTTHUMG00000130643 +254778 C8orf46 HGNC:HGNC:28498|Ensembl:ENSG00000169085|Vega:OTTHUMG00000156998 +254783 OR6C74 HGNC:HGNC:31303|Ensembl:ENSG00000197706|Vega:OTTHUMG00000165162 +254786 OR6C3 HGNC:HGNC:15437|Ensembl:ENSG00000205329|Vega:OTTHUMG00000169861 +254827 NAALADL2 MIM:608806|HGNC:HGNC:23219|Ensembl:ENSG00000177694|Vega:OTTHUMG00000157120 +254863 TMEM256 HGNC:HGNC:28618|Ensembl:ENSG00000205544|Vega:OTTHUMG00000132900 +254879 OR2T6 HGNC:HGNC:15018|Ensembl:ENSG00000198104|Vega:OTTHUMG00000040448 +254887 ZDHHC23 MIM:617334|HGNC:HGNC:28654|Ensembl:ENSG00000184307|Vega:OTTHUMG00000159335 +254896 LOC254896 Ensembl:ENSG00000173535|Vega:OTTHUMG00000097844 +254910 LCE5A MIM:612619|HGNC:HGNC:16614|Ensembl:ENSG00000186207|Vega:OTTHUMG00000014401 +254948 RPL9P8 HGNC:HGNC:30334 +254950 KRTAP15-1 HGNC:HGNC:18927|Ensembl:ENSG00000186970|Vega:OTTHUMG00000057784 +254956 MORN5 HGNC:HGNC:17841|Ensembl:ENSG00000185681|Vega:OTTHUMG00000020599 +254958 REXO1L1P HGNC:HGNC:24660|Ensembl:ENSG00000205176 +254973 OR1L4 HGNC:HGNC:8216|Ensembl:ENSG00000136939|Vega:OTTHUMG00000020620 +255022 CALHM1 MIM:612234|HGNC:HGNC:23494|Ensembl:ENSG00000185933|Vega:OTTHUMG00000018991 +255025 LINC00879 HGNC:HGNC:48566|Ensembl:ENSG00000239589 +255027 MPV17L HGNC:HGNC:26827|Ensembl:ENSG00000156968|Vega:OTTHUMG00000129882 +255031 LINC00957 HGNC:HGNC:22332 +255043 TMEM86B HGNC:HGNC:28448|Ensembl:ENSG00000180089|Vega:OTTHUMG00000187285 +255057 CBARP HGNC:HGNC:28617|Ensembl:ENSG00000099625|Vega:OTTHUMG00000180141 +255061 TAC4 MIM:607833|HGNC:HGNC:16641|Ensembl:ENSG00000176358|Vega:OTTHUMG00000161830 +255082 CASC2 MIM:608598|HGNC:HGNC:22933|Ensembl:ENSG00000177640 +255101 CFAP65 MIM:614270|HGNC:HGNC:25325|Ensembl:ENSG00000181378|Vega:OTTHUMG00000133013 +255104 TMCO4 HGNC:HGNC:27393|Ensembl:ENSG00000162542|Vega:OTTHUMG00000002697 +255119 C4orf22 HGNC:HGNC:28554|Ensembl:ENSG00000197826|Vega:OTTHUMG00000130289 +255130 IGFBP7-AS1 HGNC:HGNC:40296|Ensembl:ENSG00000245067 +255167 LINC01018 MIM:616385|HGNC:HGNC:27394|Ensembl:ENSG00000250056 +255180 GOLGA2P11 HGNC:HGNC:26788 +255187 LOC255187 Ensembl:ENSG00000250072 +255189 PLA2G4F HGNC:HGNC:27396|Ensembl:ENSG00000168907|Vega:OTTHUMG00000172782 +255193 CSNK1G2-AS1 HGNC:HGNC:28604|Ensembl:ENSG00000180846 +255208 TUBB8P9 HGNC:HGNC:42347 +255220 TXNDC8 HGNC:HGNC:31454|Ensembl:ENSG00000204193|Vega:OTTHUMG00000020481 +255231 MCOLN2 MIM:607399|HGNC:HGNC:13357|Ensembl:ENSG00000153898|Vega:OTTHUMG00000009954 +255239 ANKK1 MIM:608774|HGNC:HGNC:21027|Ensembl:ENSG00000170209|Vega:OTTHUMG00000167715 +255252 LRRC57 HGNC:HGNC:26719|Ensembl:ENSG00000180979|Vega:OTTHUMG00000130679 +255275 MYADML2 HGNC:HGNC:34548|Ensembl:ENSG00000185105|Vega:OTTHUMG00000154388 +255308 LOC255308 - +255313 CT47A11 MIM:300592|HGNC:HGNC:27397|Ensembl:ENSG00000226929|Vega:OTTHUMG00000022310 +255324 EPGN HGNC:HGNC:17470|Ensembl:ENSG00000182585|Vega:OTTHUMG00000160869 +255330 NUP210P1 HGNC:HGNC:27399|Ensembl:ENSG00000198284 +255349 TMEM211 HGNC:HGNC:33725|Ensembl:ENSG00000206069|Vega:OTTHUMG00000150790 +255374 MBLAC1 HGNC:HGNC:22180|Ensembl:ENSG00000214309|Vega:OTTHUMG00000154846 +255394 TCP11L2 HGNC:HGNC:28627|Ensembl:ENSG00000166046|Vega:OTTHUMG00000170087 +255403 ZNF718 HGNC:HGNC:26889|Ensembl:ENSG00000250312|Vega:OTTHUMG00000159873 +255411 TEX49 HGNC:HGNC:48628|Ensembl:ENSG00000257987|Vega:OTTHUMG00000170394 +255426 RASGEF1C HGNC:HGNC:27400|Ensembl:ENSG00000146090|Vega:OTTHUMG00000130914 +255480 TBX5-AS1 HGNC:HGNC:27402 +255488 RNF144B HGNC:HGNC:21578|Ensembl:ENSG00000137393|Vega:OTTHUMG00000014322 +255512 TOLLIP-AS1 HGNC:HGNC:27403|Ensembl:ENSG00000255153 +255520 ELMOD2 MIM:610196|HGNC:HGNC:28111|Ensembl:ENSG00000179387|Vega:OTTHUMG00000133417 +255620 UNC93B6 HGNC:HGNC:34053 +255626 HIST1H2BA MIM:609904|HGNC:HGNC:18730|Ensembl:ENSG00000146047|Vega:OTTHUMG00000014408 +255631 COL24A1 MIM:610025|HGNC:HGNC:20821|Ensembl:ENSG00000171502|Vega:OTTHUMG00000010629 +255649 OOSP1 HGNC:HGNC:49233|Ensembl:ENSG00000214788 +255654 LINC01743 HGNC:HGNC:52531|Ensembl:ENSG00000242042 +255725 OR52B2 HGNC:HGNC:15207|Ensembl:ENSG00000255307|Vega:OTTHUMG00000165732 +255738 PCSK9 MIM:607786|HGNC:HGNC:20001|Ensembl:ENSG00000169174|Vega:OTTHUMG00000008136 +255743 NPNT MIM:610306|HGNC:HGNC:27405|Ensembl:ENSG00000168743|Vega:OTTHUMG00000161189 +255758 TCTEX1D2 MIM:617353|HGNC:HGNC:28482|Ensembl:ENSG00000213123|Vega:OTTHUMG00000186382 +255762 PDZD9 HGNC:HGNC:28740|Ensembl:ENSG00000155714|Vega:OTTHUMG00000131586 +255783 INAFM1 HGNC:HGNC:27406|Ensembl:ENSG00000257704|Vega:OTTHUMG00000170128 +255798 SMCO1 HGNC:HGNC:27407|Ensembl:ENSG00000214097|Vega:OTTHUMG00000155581 +255809 C19orf38 HGNC:HGNC:34073|Ensembl:ENSG00000214212|Vega:OTTHUMG00000180697 +255812 SDHAP1 HGNC:HGNC:32455|Ensembl:ENSG00000185485 +255877 BCL6B MIM:608992|HGNC:HGNC:1002|Ensembl:ENSG00000161940|Vega:OTTHUMG00000177882 +255919 CNEP1R1 MIM:616869|HGNC:HGNC:26759|Ensembl:ENSG00000205423|Vega:OTTHUMG00000173447 +255926 ADAM5 HGNC:HGNC:212|Ensembl:ENSG00000196115 +255928 SYT14 MIM:610949|HGNC:HGNC:23143|Ensembl:ENSG00000143469|Vega:OTTHUMG00000036652 +255967 PAN3 MIM:617448|HGNC:HGNC:29991|Ensembl:ENSG00000152520|Vega:OTTHUMG00000016645 +256006 ANKRD31 HGNC:HGNC:26853|Ensembl:ENSG00000145700|Vega:OTTHUMG00000162649 +256021 LINC01619 HGNC:HGNC:27409|Ensembl:ENSG00000257242 +256051 ZNF549 HGNC:HGNC:26632|Ensembl:ENSG00000121406|Vega:OTTHUMG00000183465 +256076 COL6A5 MIM:611916|HGNC:HGNC:26674|Ensembl:ENSG00000172752|Vega:OTTHUMG00000159712 +256085 WRBP1 HGNC:HGNC:44010 +256126 SYCE2 MIM:611487|HGNC:HGNC:27411|Ensembl:ENSG00000161860|Vega:OTTHUMG00000180562 +256130 TMEM196 HGNC:HGNC:22431|Ensembl:ENSG00000173452|Vega:OTTHUMG00000152504 +256144 OR4C3 HGNC:HGNC:14697|Ensembl:ENSG00000176547|Vega:OTTHUMG00000166579 +256148 OR4S1 HGNC:HGNC:14705|Ensembl:ENSG00000176555|Vega:OTTHUMG00000166578 +256158 HMCN2 HGNC:HGNC:21293|Ensembl:ENSG00000148357|Vega:OTTHUMG00000140096 +256190 OR4C50P HGNC:HGNC:31274 +256223 CDRT15L2 HGNC:HGNC:34075|Ensembl:ENSG00000214819|Vega:OTTHUMG00000059557 +256227 STEAP1B HGNC:HGNC:41907|Ensembl:ENSG00000105889|Vega:OTTHUMG00000152529 +256236 NAPSB HGNC:HGNC:13396|Ensembl:ENSG00000131401 +256281 NUDT14 MIM:609219|HGNC:HGNC:20141|Ensembl:ENSG00000183828|Vega:OTTHUMG00000170372 +256297 PTF1A MIM:607194|HGNC:HGNC:23734|Ensembl:ENSG00000168267|Vega:OTTHUMG00000017815 +256302 NATD1 HGNC:HGNC:30770|Ensembl:ENSG00000274180|Vega:OTTHUMG00000130764 +256309 CCDC110 MIM:609488|HGNC:HGNC:28504|Ensembl:ENSG00000168491|Vega:OTTHUMG00000160415 +256329 LMNTD2 HGNC:HGNC:28561|Ensembl:ENSG00000185522|Vega:OTTHUMG00000132005 +256355 RPS2P32 HGNC:HGNC:30518|Ensembl:ENSG00000232818 +256356 GK5 HGNC:HGNC:28635|Ensembl:ENSG00000175066|Vega:OTTHUMG00000133572 +256364 EML3 HGNC:HGNC:26666|Ensembl:ENSG00000149499|Vega:OTTHUMG00000149817 +256369 CCDC197 HGNC:HGNC:19860|Ensembl:ENSG00000175699|Vega:OTTHUMG00000156974 +256374 LOC256374 - +256380 SCML4 HGNC:HGNC:21397|Ensembl:ENSG00000146285|Vega:OTTHUMG00000015313 +256394 SERPINA11 HGNC:HGNC:19193|Ensembl:ENSG00000186910|Vega:OTTHUMG00000171348 +256435 ST6GALNAC3 MIM:610133|HGNC:HGNC:19343|Ensembl:ENSG00000184005|Vega:OTTHUMG00000009615 +256471 MFSD8 MIM:611124|HGNC:HGNC:28486|Ensembl:ENSG00000164073|Vega:OTTHUMG00000133303 +256472 TMEM151A HGNC:HGNC:28497|Ensembl:ENSG00000179292|Vega:OTTHUMG00000166920 +256536 TCERG1L HGNC:HGNC:23533|Ensembl:ENSG00000176769|Vega:OTTHUMG00000019276 +256586 LYSMD2 HGNC:HGNC:28571|Ensembl:ENSG00000140280|Vega:OTTHUMG00000131804 +256643 BCLAF3 HGNC:HGNC:27413|Ensembl:ENSG00000173681|Vega:OTTHUMG00000021226 +256646 NUTM1 MIM:608963|HGNC:HGNC:29919|Ensembl:ENSG00000184507|Vega:OTTHUMG00000172348 +256691 MAMDC2 MIM:612879|HGNC:HGNC:23673|Ensembl:ENSG00000165072|Vega:OTTHUMG00000019990 +256710 GLIPR1L1 MIM:610395|HGNC:HGNC:28392|Ensembl:ENSG00000173401|Vega:OTTHUMG00000169755 +256714 MAP7D2 HGNC:HGNC:25899|Ensembl:ENSG00000184368|Vega:OTTHUMG00000021228 +256764 WDR72 MIM:613214|HGNC:HGNC:26790|Ensembl:ENSG00000166415|Vega:OTTHUMG00000131939 +256815 C10orf67 HGNC:HGNC:28716|Ensembl:ENSG00000179133|Vega:OTTHUMG00000017818 +256880 LOC256880 Ensembl:ENSG00000245322 +256892 OR51F1 HGNC:HGNC:15196|Ensembl:ENSG00000280021|Vega:OTTHUMG00000066503 +256933 NPB MIM:607996|HGNC:HGNC:30099|Ensembl:ENSG00000183979|Vega:OTTHUMG00000177983 +256949 KANK3 MIM:614611|HGNC:HGNC:24796|Ensembl:ENSG00000186994|Vega:OTTHUMG00000182461 +256957 HEATR9 HGNC:HGNC:26548|Ensembl:ENSG00000270379|Vega:OTTHUMG00000188393 +256979 SUN3 HGNC:HGNC:22429|Ensembl:ENSG00000164744|Vega:OTTHUMG00000155646 +256987 SERINC5 MIM:614551|HGNC:HGNC:18825|Ensembl:ENSG00000164300|Vega:OTTHUMG00000162563 +257000 TINCR MIM:615241|HGNC:HGNC:14607|Ensembl:ENSG00000223573|Vega:OTTHUMG00000150390 +257019 FRMD3 MIM:607619|HGNC:HGNC:24125|Ensembl:ENSG00000172159|Vega:OTTHUMG00000020103 +257044 CATSPERE MIM:617510|HGNC:HGNC:28491|Ensembl:ENSG00000179397|Vega:OTTHUMG00000040103 +257062 CATSPERD MIM:617490|HGNC:HGNC:28598|Ensembl:ENSG00000174898|Vega:OTTHUMG00000143036 +257068 PLCXD2 MIM:617015|HGNC:HGNC:26462|Ensembl:ENSG00000240891|Vega:OTTHUMG00000159279 +257093 PSME2P1 HGNC:HGNC:20632 +257101 ZNF683 MIM:616775|HGNC:HGNC:28495|Ensembl:ENSG00000176083|Vega:OTTHUMG00000003521 +257106 ARHGAP30 MIM:614264|HGNC:HGNC:27414|Ensembl:ENSG00000186517|Vega:OTTHUMG00000031477 +257144 GCSAM MIM:607792|HGNC:HGNC:20253|Ensembl:ENSG00000174500|Vega:OTTHUMG00000159231 +257160 RNF214 HGNC:HGNC:25335|Ensembl:ENSG00000167257|Vega:OTTHUMG00000167069 +257169 C9orf43 HGNC:HGNC:23570|Ensembl:ENSG00000157653|Vega:OTTHUMG00000020526 +257177 CFAP126 MIM:616119|HGNC:HGNC:32325|Ensembl:ENSG00000188931|Vega:OTTHUMG00000034462 +257194 NEGR1 MIM:613173|HGNC:HGNC:17302|Ensembl:ENSG00000172260|Vega:OTTHUMG00000009698 +257202 GPX6 MIM:607913|HGNC:HGNC:4558|Ensembl:ENSG00000198704|Vega:OTTHUMG00000044828 +257203 DSCR9 HGNC:HGNC:16301|Ensembl:ENSG00000230366 +257218 SHPRH MIM:608048|HGNC:HGNC:19336|Ensembl:ENSG00000146414|Vega:OTTHUMG00000015750 +257236 CCDC96 HGNC:HGNC:26900|Ensembl:ENSG00000173013|Vega:OTTHUMG00000125511 +257240 KLHL34 HGNC:HGNC:26634|Ensembl:ENSG00000185915|Vega:OTTHUMG00000021234 +257313 UTS2B HGNC:HGNC:30894|Ensembl:ENSG00000188958|Vega:OTTHUMG00000156192 +257358 LINC01366 HGNC:HGNC:27416 +257364 SNX33 HGNC:HGNC:28468|Ensembl:ENSG00000173548|Vega:OTTHUMG00000142835 +257396 LOC257396 Ensembl:ENSG00000247796 +257397 TAB3 MIM:300480|HGNC:HGNC:30681|Ensembl:ENSG00000157625|Vega:OTTHUMG00000021329 +257407 C2orf72 HGNC:HGNC:27418|Ensembl:ENSG00000204128|Vega:OTTHUMG00000153996 +257415 FAM133B HGNC:HGNC:28629|Ensembl:ENSG00000234545|Vega:OTTHUMG00000155863 +257468 MEIS3P2 HGNC:HGNC:17638 +257629 ANKS4B MIM:609901|HGNC:HGNC:26795|Ensembl:ENSG00000175311|Vega:OTTHUMG00000177371 +257641 NPCA1 MIM:607107 +258010 SVIP HGNC:HGNC:25238|Ensembl:ENSG00000198168|Vega:OTTHUMG00000166072 +259173 ALS2CL MIM:612402|HGNC:HGNC:20605|Ensembl:ENSG00000178038|Vega:OTTHUMG00000128673 +259197 NCR3 MIM:611550|HGNC:HGNC:19077|Ensembl:ENSG00000204475|Vega:OTTHUMG00000031123 +259215 LY6G6F MIM:611404|HGNC:HGNC:13933|Ensembl:ENSG00000204424|Vega:OTTHUMG00000031252 +259217 HSPA12A MIM:610701|HGNC:HGNC:19022|Ensembl:ENSG00000165868|Vega:OTTHUMG00000019107 +259230 SGMS1 MIM:611573|HGNC:HGNC:29799|Ensembl:ENSG00000198964|Vega:OTTHUMG00000018231 +259232 NALCN MIM:611549|HGNC:HGNC:19082|Ensembl:ENSG00000102452|Vega:OTTHUMG00000017295 +259234 DSCR10 HGNC:HGNC:16302|Ensembl:ENSG00000233316 +259236 TMIE MIM:607237|HGNC:HGNC:30800|Ensembl:ENSG00000181585|Vega:OTTHUMG00000149909 +259239 WFDC11 HGNC:HGNC:20478|Ensembl:ENSG00000180083|Vega:OTTHUMG00000046330 +259240 WFDC9 HGNC:HGNC:20380|Ensembl:ENSG00000180205|Vega:OTTHUMG00000046332 +259249 MRGPRX1 MIM:607227|HGNC:HGNC:17962|Ensembl:ENSG00000170255|Vega:OTTHUMG00000162655 +259265 bA255A11.4 - +259266 ASPM MIM:605481|HGNC:HGNC:19048|Ensembl:ENSG00000066279|Vega:OTTHUMG00000036277 +259282 BOD1L1 MIM:616746|HGNC:HGNC:31792|Ensembl:ENSG00000038219|Vega:OTTHUMG00000090659 +259283 MDS2 MIM:607305|HGNC:HGNC:29633|Ensembl:ENSG00000197880|Vega:OTTHUMG00000002927 +259285 TAS2R39 HGNC:HGNC:18886|Ensembl:ENSG00000236398|Vega:OTTHUMG00000152636 +259286 TAS2R40 MIM:613964|HGNC:HGNC:18885|Ensembl:ENSG00000221937|Vega:OTTHUMG00000152638 +259287 TAS2R41 MIM:613965|HGNC:HGNC:18883|Ensembl:ENSG00000221855|Vega:OTTHUMG00000155892 +259289 TAS2R43 MIM:612668|HGNC:HGNC:18875|Ensembl:ENSG00000255374|Vega:OTTHUMG00000165352 +259290 TAS2R31 MIM:612669|HGNC:HGNC:19113|Ensembl:ENSG00000256436|Vega:OTTHUMG00000168558 +259291 TAS2R45 MIM:613967|HGNC:HGNC:18876 +259292 TAS2R46 MIM:612774|HGNC:HGNC:18877|Ensembl:ENSG00000226761|Vega:OTTHUMG00000165351 +259293 TAS2R30 MIM:613963|HGNC:HGNC:19112|Ensembl:ENSG00000256188|Vega:OTTHUMG00000168562 +259294 TAS2R19 MIM:613961|HGNC:HGNC:19108|Ensembl:ENSG00000212124|Vega:OTTHUMG00000162687 +259295 TAS2R20 MIM:613962|HGNC:HGNC:19109|Ensembl:ENSG00000255837|Vega:OTTHUMG00000162695 +259296 TAS2R50 MIM:609627|HGNC:HGNC:18882|Ensembl:ENSG00000212126|Vega:OTTHUMG00000162719 +259307 IL4I1 MIM:609742|HGNC:HGNC:19094|Ensembl:ENSG00000104951|Vega:OTTHUMG00000183377 +259308 FAM205A HGNC:HGNC:41911|Ensembl:ENSG00000205108|Vega:OTTHUMG00000000448 +260293 CYP4X1 MIM:614999|HGNC:HGNC:20244|Ensembl:ENSG00000186377|Vega:OTTHUMG00000008017 +260294 NSUN5P2 HGNC:HGNC:16609|Ensembl:ENSG00000106133 +260328 ALRH MIM:607154 +260330 ALPPP HGNC:HGNC:14016 +260331 LOC260331 - +260332 ECEL1P3 HGNC:HGNC:14018 +260334 TUBB8P12 HGNC:HGNC:24983 +260335 ELF2P2 HGNC:HGNC:24610 +260336 ELF2P3 HGNC:HGNC:24611 +260337 UHRF2P1 HGNC:HGNC:39565 +260338 TUBB8P4 HGNC:HGNC:42185 +260339 LOC260339 - +260340 TFAMP2 HGNC:HGNC:11638 +260341 TFAMP1 HGNC:HGNC:11636 +260342 COPS8P1 HGNC:HGNC:45269 +260402 IS1 MIM:181800 +260403 MMEDF MIM:607131 +260415 SCASI MIM:607317|HGNC:HGNC:19186 +260421 LOC260421 - +260422 LOC260422 - +260425 MAGI3 MIM:615943|HGNC:HGNC:29647|Ensembl:ENSG00000081026|Vega:OTTHUMG00000011737 +260429 PRSS33 MIM:613797|HGNC:HGNC:30405|Ensembl:ENSG00000103355|Vega:OTTHUMG00000177360 +260431 COPD MIM:606963 +260432 SLSN3 MIM:606995 +260434 PYDC1 MIM:615700|HGNC:HGNC:30261|Ensembl:ENSG00000169900|Vega:OTTHUMG00000132407 +260436 FDCSP MIM:607241|HGNC:HGNC:19215|Ensembl:ENSG00000181617|Vega:OTTHUMG00000129393 +261726 TIPRL MIM:611807|HGNC:HGNC:30231|Ensembl:ENSG00000143155|Vega:OTTHUMG00000034646 +261727 CRCL MIM:607135 +261729 STEAP2 MIM:605094|HGNC:HGNC:17885|Ensembl:ENSG00000157214|Vega:OTTHUMG00000023341 +261734 NPHP4 MIM:607215|HGNC:HGNC:19104|Ensembl:ENSG00000131697|Vega:OTTHUMG00000000701 +261735 TVP23CP2 HGNC:HGNC:44647 +266553 OFCC1 MIM:614287|HGNC:HGNC:21017|Ensembl:ENSG00000181355|Vega:OTTHUMG00000159104 +266619 NOS2P4 HGNC:HGNC:50720 +266623 SLC25A5P1 HGNC:HGNC:19250 +266625 NDUFA9P1 HGNC:HGNC:19252 +266626 CLCP1 HGNC:HGNC:19257 +266629 SEC14L3 MIM:612824|HGNC:HGNC:18655|Ensembl:ENSG00000100012|Vega:OTTHUMG00000151259 +266643 EDDM3CP HGNC:HGNC:19224 +266655 LINC00094 HGNC:HGNC:24742|Ensembl:ENSG00000235106|Vega:OTTHUMG00000020880 +266656 TAS2R12P HGNC:HGNC:19103 +266657 TAS2R15P HGNC:HGNC:19106 +266661 TAS2R22 HGNC:HGNC:19110 +266665 TAS2R33 HGNC:HGNC:19114 +266666 TAS2R36 HGNC:HGNC:19115 +266667 TAS2R37 HGNC:HGNC:19116 +266673 ZNF402P HGNC:HGNC:19292 +266675 BEST4 MIM:607336|HGNC:HGNC:17106|Ensembl:ENSG00000142959|Vega:OTTHUMG00000008488 +266678 MRX81 MIM:300433|HGNC:HGNC:19301 +266683 LOC266683 - +266691 DYX6 MIM:606616|HGNC:HGNC:19352 +266693 EZH2P1 HGNC:HGNC:39918 +266694 LOC266694 - +266695 PHF2P1 HGNC:HGNC:30241 +266697 POM121L4P HGNC:HGNC:19326 +266698 ARHGAP42P3 HGNC:HGNC:19327 +266699 FABP5P11 HGNC:HGNC:19328 +266700 BMP6P1 HGNC:HGNC:19329 +266701 SOCS2P2 HGNC:HGNC:19330 +266703 ASH2LP1 HGNC:HGNC:19332 +266710 COMA MIM:257550 +266719 RRDX MIM:300378 +266722 HS6ST3 MIM:609401|HGNC:HGNC:19134|Ensembl:ENSG00000185352|Vega:OTTHUMG00000017232 +266723 PSMC6P1 HGNC:HGNC:20634 +266724 HSPA9P1 HGNC:HGNC:24915 +266726 DYX7 HGNC:HGNC:19324 +266727 MDGA1 MIM:609626|HGNC:HGNC:19267|Ensembl:ENSG00000112139|Vega:OTTHUMG00000014626 +266740 MAGEA2B MIM:300549|HGNC:HGNC:19340|Ensembl:ENSG00000183305|Vega:OTTHUMG00000022645 +266743 NPAS4 MIM:608554|HGNC:HGNC:18983|Ensembl:ENSG00000174576|Vega:OTTHUMG00000167045 +266747 RGL4 MIM:612214|HGNC:HGNC:31911|Ensembl:ENSG00000159496|Vega:OTTHUMG00000150711 +266783 PSMD2P1 HGNC:HGNC:30154 +266785 NUP50P2 HGNC:HGNC:29928 +266786 NUP50P3 HGNC:HGNC:29927 +266789 EPPS MIM:607221 +266790 HCA1 MIM:607258 +266811 NPSA - +266812 NAP1L5 MIM:612203|HGNC:HGNC:19968|Ensembl:ENSG00000177432|Vega:OTTHUMG00000130950 +266917 D21S2088E Ensembl:ENSG00000228592 +266919 LINC00307 HGNC:HGNC:16727|Ensembl:ENSG00000227342 +266920 AK2P1 HGNC:HGNC:24037 +266954 CABYRP1 HGNC:HGNC:31902 +266971 PIPSL HGNC:HGNC:23733|Ensembl:ENSG00000180764 +266977 ADGRF1 MIM:617430|HGNC:HGNC:18990|Ensembl:ENSG00000153292|Vega:OTTHUMG00000014795 +266979 CTRCT27 MIM:607304 +267002 PGBD2 HGNC:HGNC:19399|Ensembl:ENSG00000185220|Vega:OTTHUMG00000040424 +267004 PGBD3 HGNC:HGNC:19400|Ensembl:ENSG00000225830 +267005 PGBD3P1 HGNC:HGNC:19402 +267006 PGBD3P2 HGNC:HGNC:19397 +267007 PGBD3P3 HGNC:HGNC:19396 +267008 PGBD3P4 HGNC:HGNC:19379 +267009 RPS9P2 HGNC:HGNC:19428 +267010 RNU12 HGNC:HGNC:19380|Ensembl:ENSG00000276027 +267012 DAOA MIM:607408|HGNC:HGNC:21191|Ensembl:ENSG00000182346|Vega:OTTHUMG00000041333 +267013 HLA-DPA3 HGNC:HGNC:19393 +267014 HLA-N HGNC:HGNC:19406 +267015 HLA-S HGNC:HGNC:19395 +267016 HLA-X HGNC:HGNC:19385 +267017 HLA-Z HGNC:HGNC:19394 +267020 ATP5L2 HGNC:HGNC:13213|Ensembl:ENSG00000249222|Vega:OTTHUMG00000150890 +268276 LOC268276 - +276719 SOCS2P1 HGNC:HGNC:16069 +280636 SELENOH MIM:607914|HGNC:HGNC:18251|Ensembl:ENSG00000211450|Vega:OTTHUMG00000167202 +280637 PSMD7P1 HGNC:HGNC:7202 +280644 PSMD10P2 HGNC:HGNC:30151 +280655 IGBP1P1 HGNC:HGNC:19709 +280657 SSX6 MIM:300541|HGNC:HGNC:19652 +280658 SSX7 MIM:300542|HGNC:HGNC:19653|Ensembl:ENSG00000187754|Vega:OTTHUMG00000021572 +280659 SSX8 MIM:300543|HGNC:HGNC:19654 +280660 SSX9 MIM:300544|HGNC:HGNC:19655|Ensembl:ENSG00000204648 +280661 EIF1AXP1 HGNC:HGNC:19900 +280664 WFDC10B HGNC:HGNC:20479|Ensembl:ENSG00000182931|Vega:OTTHUMG00000130227 +282549 STQTL3 MIM:606257 +282550 STQTL4 MIM:606258 +282551 ITS MIM:606960 +282552 IS2 MIM:607354 +282553 AUTS8 MIM:607373 +282566 LINC00515 HGNC:HGNC:16019|Ensembl:ENSG00000260583 +282569 BACE2-IT1 HGNC:HGNC:16024 +282616 IFNL2 MIM:607401|HGNC:HGNC:18364|Ensembl:ENSG00000183709|Vega:OTTHUMG00000182806 +282617 IFNL3 MIM:607402|HGNC:HGNC:18365|Ensembl:ENSG00000197110|Vega:OTTHUMG00000182805 +282618 IFNL1 MIM:607403|HGNC:HGNC:18363|Ensembl:ENSG00000182393|Vega:OTTHUMG00000182807 +282631 GCCD2 MIM:607398 +282679 AQP11 MIM:609914|HGNC:HGNC:19940|Ensembl:ENSG00000178301|Vega:OTTHUMG00000165194 +282694 NASPP1 HGNC:HGNC:29910 +282697 DIS3L2P1 HGNC:HGNC:14021 +282706 DAOA-AS1 MIM:607415|HGNC:HGNC:30243|Ensembl:ENSG00000232307 +282754 OR4D12P HGNC:HGNC:19587 +282756 OR7E149P HGNC:HGNC:19589 +282763 OR51B5 HGNC:HGNC:19599|Ensembl:ENSG00000242180|Vega:OTTHUMG00000066676 +282769 OR10AF1P HGNC:HGNC:19606 +282770 OR10AG1 HGNC:HGNC:19607|Ensembl:ENSG00000174970|Vega:OTTHUMG00000166824 +282775 OR5J2 HGNC:HGNC:19612|Ensembl:ENSG00000174957|Vega:OTTHUMG00000166835 +282776 OR8V1P HGNC:HGNC:19613 +282786 OR8G7P HGNC:HGNC:19625 +282790 OR5BT1P HGNC:HGNC:19629 +282791 OR8T1P HGNC:HGNC:19630 +282795 OR11P1P HGNC:HGNC:19636 +282801 OR7E148P HGNC:HGNC:19642 +282808 RAB40AL MIM:300405|HGNC:HGNC:25410|Ensembl:ENSG00000102128|Vega:OTTHUMG00000022084 +282809 POC1B MIM:614784|HGNC:HGNC:30836|Ensembl:ENSG00000139323|Vega:OTTHUMG00000169944 +282849 SLEN3 MIM:607967|HGNC:HGNC:18544 +282890 ZNF311 HGNC:HGNC:13847|Ensembl:ENSG00000197935|Vega:OTTHUMG00000031292 +282966 C10orf53 HGNC:HGNC:27421|Ensembl:ENSG00000178645|Vega:OTTHUMG00000018199 +282967 MAPK6PS6 HGNC:HGNC:18978 +282969 FUOM HGNC:HGNC:24733|Ensembl:ENSG00000148803|Vega:OTTHUMG00000019315 +282973 JAKMIP3 MIM:611198|HGNC:HGNC:23523|Ensembl:ENSG00000188385|Vega:OTTHUMG00000150167 +282974 STK32C HGNC:HGNC:21332|Ensembl:ENSG00000165752|Vega:OTTHUMG00000019285 +282980 LINC00700 HGNC:HGNC:27422|Ensembl:ENSG00000234962 +282991 BLOC1S2 MIM:609768|HGNC:HGNC:20984|Ensembl:ENSG00000196072|Vega:OTTHUMG00000018908 +282996 RBM20 MIM:613171|HGNC:HGNC:27424|Ensembl:ENSG00000203867|Vega:OTTHUMG00000019043 +282997 PDCD4-AS1 HGNC:HGNC:27425 +283008 NUTM2E HGNC:HGNC:23448 +283011 FLJ37201 - +283014 EIF2S2P3 HGNC:HGNC:31664 +283025 LINC01553 HGNC:HGNC:23524|Ensembl:ENSG00000235931 +283028 LOC283028 - +283033 LINC00841 HGNC:HGNC:27430 +283038 LOC283038 Ensembl:ENSG00000228021 +283045 LOC283045 - +283050 ZMIZ1-AS1 HGNC:HGNC:27433|Ensembl:ENSG00000224596 +283078 MKX MIM:601332|HGNC:HGNC:23729|Ensembl:ENSG00000150051|Vega:OTTHUMG00000017862 +283080 C10orf126 HGNC:HGNC:28693 +283089 WDR11-AS1 HGNC:HGNC:27437|Ensembl:ENSG00000227165 +283092 OR4C13 HGNC:HGNC:15169|Ensembl:ENSG00000258817|Vega:OTTHUMG00000166686 +283093 OR4C12 HGNC:HGNC:15168|Ensembl:ENSG00000221954|Vega:OTTHUMG00000166687 +283102 KRT8P41 HGNC:HGNC:39875|Ensembl:ENSG00000213538 +283104 SBF2-AS1 HGNC:HGNC:27438|Ensembl:ENSG00000246273 +283106 CSNK2A3 HGNC:HGNC:2458|Ensembl:ENSG00000254598|Vega:OTTHUMG00000165708 +283110 OR52Z1 HGNC:HGNC:19596|Vega:OTTHUMG00000066624 +283111 OR51V1 HGNC:HGNC:19597|Ensembl:ENSG00000176742|Vega:OTTHUMG00000066671 +283114 RPS25P1 HGNC:HGNC:34027 +283116 TRIM49B HGNC:HGNC:42955|Ensembl:ENSG00000182053|Vega:OTTHUMG00000186986 +283120 H19 MIM:103280|HGNC:HGNC:4713|Ensembl:ENSG00000130600 +283129 MAJIN MIM:617130|HGNC:HGNC:27441|Ensembl:ENSG00000168070|Vega:OTTHUMG00000165632 +283130 SLC25A45 MIM:610825|HGNC:HGNC:27442|Ensembl:ENSG00000162241|Vega:OTTHUMG00000166255 +283131 NEAT1 MIM:612769|HGNC:HGNC:30815|Ensembl:ENSG00000245532 +283140 LOC283140 Ensembl:ENSG00000250303 +283143 LINC00900 HGNC:HGNC:27444 +283149 BCL9L MIM:609004|HGNC:HGNC:23688|Ensembl:ENSG00000186174|Vega:OTTHUMG00000166414 +283150 FOXR1 MIM:615755|HGNC:HGNC:29980|Ensembl:ENSG00000176302|Vega:OTTHUMG00000166347 +283152 CCDC153 HGNC:HGNC:27446|Ensembl:ENSG00000248712|Vega:OTTHUMG00000156903 +283159 OR8D1 HGNC:HGNC:8481|Ensembl:ENSG00000196341|Vega:OTTHUMG00000165977 +283160 OR8D2 HGNC:HGNC:8482|Ensembl:ENSG00000279116|Vega:OTTHUMG00000165978 +283162 OR8B4 HGNC:HGNC:8473|Ensembl:ENSG00000280090|Vega:OTTHUMG00000165916 +283165 KIRREL3-AS3 HGNC:HGNC:26855|Ensembl:ENSG00000218109 +283171 C11orf44 HGNC:HGNC:26805 +283172 LOC283172 - +283174 MIR4697HG HGNC:HGNC:27448|Ensembl:ENSG00000280237 +283177 LOC283177 - +283189 OR9G4 HGNC:HGNC:15322|Ensembl:ENSG00000172457|Vega:OTTHUMG00000166932 +283193 OR5AZ1P HGNC:HGNC:15262 +283194 LOC283194 Ensembl:ENSG00000255240 +283197 LINC00301 HGNC:HGNC:28603|Ensembl:ENSG00000181995 +283208 P4HA3 MIM:608987|HGNC:HGNC:30135|Ensembl:ENSG00000149380|Vega:OTTHUMG00000165254 +283209 PGM2L1 MIM:611610|HGNC:HGNC:20898|Ensembl:ENSG00000165434|Vega:OTTHUMG00000168132 +283212 KLHL35 HGNC:HGNC:26597|Ensembl:ENSG00000149243 +283214 LOC283214 Ensembl:ENSG00000247867 +283219 KCTD21 HGNC:HGNC:27452|Ensembl:ENSG00000188997|Vega:OTTHUMG00000166497 +283226 FNTAP1 HGNC:HGNC:3783 +283229 CRACR2B MIM:614177|HGNC:HGNC:28703|Ensembl:ENSG00000177685|Vega:OTTHUMG00000165267 +283232 TMEM80 HGNC:HGNC:27453|Ensembl:ENSG00000177042|Vega:OTTHUMG00000133307 +283234 CCDC88B MIM:611205|HGNC:HGNC:26757|Ensembl:ENSG00000168071|Vega:OTTHUMG00000045419 +283236 EEF1DP8 HGNC:HGNC:51458 +283237 TTC9C HGNC:HGNC:28432|Ensembl:ENSG00000162222|Vega:OTTHUMG00000167607 +283238 SLC22A24 MIM:611698|HGNC:HGNC:28542|Ensembl:ENSG00000197658|Vega:OTTHUMG00000165372 +283248 RCOR2 MIM:616019|HGNC:HGNC:27455|Ensembl:ENSG00000167771|Vega:OTTHUMG00000150472 +283254 HARBI1 MIM:615086|HGNC:HGNC:26522|Ensembl:ENSG00000180423|Vega:OTTHUMG00000166537 +283257 TRIM51FP HGNC:HGNC:43966 +283267 LINC00294 MIM:612296|HGNC:HGNC:27456|Ensembl:ENSG00000280798 +283284 IGSF22 HGNC:HGNC:26750|Ensembl:ENSG00000179057|Vega:OTTHUMG00000160502 +283297 OR10A4 HGNC:HGNC:15130|Ensembl:ENSG00000170782|Vega:OTTHUMG00000165740 +283298 OLFML1 HGNC:HGNC:24473|Ensembl:ENSG00000183801|Vega:OTTHUMG00000165527 +283299 LOC283299 Ensembl:ENSG00000254951 +283303 MRGPRG-AS1 HGNC:HGNC:26691|Ensembl:ENSG00000236301 +283310 OTOGL MIM:614925|HGNC:HGNC:26901|Ensembl:ENSG00000165899|Vega:OTTHUMG00000150509 +283314 C1RL-AS1 HGNC:HGNC:27461|Ensembl:ENSG00000205885 +283316 CD163L1 MIM:606079|HGNC:HGNC:30375|Ensembl:ENSG00000177675|Vega:OTTHUMG00000168325 +283320 HSPD1P12 HGNC:HGNC:35140 +283332 LINC02396 HGNC:HGNC:27463|Ensembl:ENSG00000258135 +283335 LOC283335 Ensembl:ENSG00000257337 +283337 ZNF740 HGNC:HGNC:27465|Ensembl:ENSG00000139651|Vega:OTTHUMG00000170027 +283345 RPL13P5 HGNC:HGNC:30363|Ensembl:ENSG00000240370 +283349 RASSF3 MIM:607019|HGNC:HGNC:14271|Ensembl:ENSG00000153179|Vega:OTTHUMG00000168812 +283352 TMEM132D-AS1 HGNC:HGNC:27466|Ensembl:ENSG00000249196 +283358 B4GALNT3 MIM:612220|HGNC:HGNC:24137|Ensembl:ENSG00000139044|Vega:OTTHUMG00000129283 +283365 OR6C6 HGNC:HGNC:31293|Ensembl:ENSG00000188324|Vega:OTTHUMG00000168101 +283373 ANKRD52 HGNC:HGNC:26614|Ensembl:ENSG00000139645|Vega:OTTHUMG00000170329 +283375 SLC39A5 MIM:608730|HGNC:HGNC:20502|Ensembl:ENSG00000139540|Vega:OTTHUMG00000156962 +283377 SPRYD4 HGNC:HGNC:27468|Ensembl:ENSG00000176422|Vega:OTTHUMG00000187405 +283383 ADGRD1 MIM:613639|HGNC:HGNC:19893|Ensembl:ENSG00000111452|Vega:OTTHUMG00000168339 +283385 MORN3 HGNC:HGNC:29807|Ensembl:ENSG00000139714|Vega:OTTHUMG00000169075 +283387 LOC283387 - +283392 TRHDE-AS1 HGNC:HGNC:27471|Ensembl:ENSG00000236333 +283398 SUCLG2P2 HGNC:HGNC:43997 +283403 C12orf80 HGNC:HGNC:27473 +283404 LINC00592 HGNC:HGNC:27474|Ensembl:ENSG00000258279 +283412 RPL29P12 HGNC:HGNC:36608 +283416 LINC01465 HGNC:HGNC:26364|Ensembl:ENSG00000221949 +283417 DPY19L2 MIM:613893|HGNC:HGNC:19414|Ensembl:ENSG00000177990|Vega:OTTHUMG00000168712 +283420 CLEC9A MIM:612252|HGNC:HGNC:26705|Ensembl:ENSG00000197992|Vega:OTTHUMG00000168398 +283422 LINC01559 HGNC:HGNC:26598|Ensembl:ENSG00000180861 +283431 GAS2L3 MIM:617224|HGNC:HGNC:27475|Ensembl:ENSG00000139354|Vega:OTTHUMG00000170439 +283432 LINC00485 HGNC:HGNC:27476|Ensembl:ENSG00000258169 +283435 LOC283435 - +283440 ITFG2-AS1 HGNC:HGNC:53128|Ensembl:ENSG00000255669 +283446 MYO1H MIM:614636|HGNC:HGNC:13879|Ensembl:ENSG00000174527|Vega:OTTHUMG00000169252 +283450 HECTD4 HGNC:HGNC:26611|Ensembl:ENSG00000173064|Vega:OTTHUMG00000150719 +283455 KSR2 MIM:610737|HGNC:HGNC:18610|Ensembl:ENSG00000171435|Vega:OTTHUMG00000169020 +283458 NME2P1 HGNC:HGNC:31358 +283459 GATC MIM:617210|HGNC:HGNC:25068|Ensembl:ENSG00000257218|Vega:OTTHUMG00000047788 +283460 HNF1A-AS1 HGNC:HGNC:26785|Ensembl:ENSG00000241388 +283461 C12orf40 HGNC:HGNC:26846|Ensembl:ENSG00000180116|Vega:OTTHUMG00000133567 +283463 MUC19 MIM:612170|HGNC:HGNC:14362 +283464 GXYLT1 MIM:613321|HGNC:HGNC:27482|Ensembl:ENSG00000151233|Vega:OTTHUMG00000169379 +283471 TMPRSS12 HGNC:HGNC:28779|Ensembl:ENSG00000186452|Vega:OTTHUMG00000169483 +283480 FGF14-IT1 HGNC:HGNC:42774|Ensembl:ENSG00000243319 +283481 FGF14-AS2 HGNC:HGNC:44368|Ensembl:ENSG00000272143 +283483 LINC00551 HGNC:HGNC:43691|Ensembl:ENSG00000272274 +283486 LINC00567 HGNC:HGNC:43711|Ensembl:ENSG00000259831 +283487 LINC00346 HGNC:HGNC:27492|Ensembl:ENSG00000255874 +283489 CHAMP1 MIM:616327|HGNC:HGNC:20311|Ensembl:ENSG00000198824|Vega:OTTHUMG00000017404 +283491 OR7E156P HGNC:HGNC:31311 +283507 SUGT1P3 HGNC:HGNC:20513|Ensembl:ENSG00000239827 +283514 SIAH3 MIM:615609|HGNC:HGNC:30553|Ensembl:ENSG00000215475|Vega:OTTHUMG00000016862 +283518 KCNRG MIM:607947|HGNC:HGNC:18893|Ensembl:ENSG00000198553|Vega:OTTHUMG00000140140 +283521 LINC00282 HGNC:HGNC:26737|Ensembl:ENSG00000281106|Vega:OTTHUMG00000189519 +283523 TERF1P5 HGNC:HGNC:39686 +283537 SLC46A3 MIM:616764|HGNC:HGNC:27501|Ensembl:ENSG00000139508|Vega:OTTHUMG00000016650 +283547 LINC00639 HGNC:HGNC:27502|Ensembl:ENSG00000259070 +283551 LINC01588 HGNC:HGNC:27503|Ensembl:ENSG00000214900 +283553 LINC00640 HGNC:HGNC:44291|Ensembl:ENSG00000258479 +283554 GPR137C HGNC:HGNC:25445|Ensembl:ENSG00000180998|Vega:OTTHUMG00000171104 +283556 UBE2L1 MIM:600012|HGNC:HGNC:12486 +283562 RPL21P9 HGNC:HGNC:19780 +283571 PROX2 MIM:615094|HGNC:HGNC:26715|Ensembl:ENSG00000119608|Vega:OTTHUMG00000171481 +283575 LINC02288 HGNC:HGNC:27505|Ensembl:ENSG00000246548 +283576 ZDHHC22 HGNC:HGNC:20106|Ensembl:ENSG00000177108|Vega:OTTHUMG00000171575 +283578 TMED8 HGNC:HGNC:18633|Ensembl:ENSG00000100580|Vega:OTTHUMG00000171552 +283579 C14orf178 HGNC:HGNC:26385|Ensembl:ENSG00000197734|Vega:OTTHUMG00000171528 +283585 LINC01148 HGNC:HGNC:27507|Ensembl:ENSG00000258804 +283587 LINC01146 HGNC:HGNC:49467|Ensembl:ENSG00000258867 +283592 FAM181A-AS1 HGNC:HGNC:20133|Ensembl:ENSG00000258584 +283596 SNHG10 HGNC:HGNC:27510 +283598 C14orf177 HGNC:HGNC:26375|Ensembl:ENSG00000176605|Vega:OTTHUMG00000167745 +283600 SLC25A47 MIM:609911|HGNC:HGNC:20115|Ensembl:ENSG00000140107|Vega:OTTHUMG00000171571 +283601 LINC00523 HGNC:HGNC:20117|Ensembl:ENSG00000196273 +283603 RPL26P4 HGNC:HGNC:19807 +283617 OR4K3 HGNC:HGNC:14731 +283624 LINC00641 HGNC:HGNC:27511|Ensembl:ENSG00000258441 +283629 TSSK4 MIM:610711|HGNC:HGNC:19825|Ensembl:ENSG00000139908|Vega:OTTHUMG00000029323 +283631 BTF3P2 HGNC:HGNC:19924 +283635 FAM177A1 HGNC:HGNC:19829|Ensembl:ENSG00000151327|Vega:OTTHUMG00000140217 +283638 CEP170B HGNC:HGNC:20362|Ensembl:ENSG00000099814|Vega:OTTHUMG00000170763 +283643 C14orf80 HGNC:HGNC:20127|Ensembl:ENSG00000185347|Vega:OTTHUMG00000170426 +283651 HMGN2P46 MIM:611314|HGNC:HGNC:26817 +283652 SLC24A5 MIM:609802|HGNC:HGNC:20611|Ensembl:ENSG00000188467|Vega:OTTHUMG00000131494 +283659 PRTG MIM:613261|HGNC:HGNC:26373|Ensembl:ENSG00000166450|Vega:OTTHUMG00000172591 +283663 LINC00926 HGNC:HGNC:27514|Ensembl:ENSG00000247982 +283665 LOC283665 - +283673 EWSAT1 MIM:616492|HGNC:HGNC:26596|Ensembl:ENSG00000212766 +283677 REC114 HGNC:HGNC:25065|Ensembl:ENSG00000183324|Vega:OTTHUMG00000172549 +283682 LINC01579 HGNC:HGNC:27519 +283683 LOC283683 Ensembl:ENSG00000274253 +283685 GOLGA6L2 HGNC:HGNC:26695|Ensembl:ENSG00000174450|Vega:OTTHUMG00000176417 +283687 ST20-AS1 HGNC:HGNC:27521 +283688 LINC00927 HGNC:HGNC:27522|Ensembl:ENSG00000259361 +283692 CPEB1-AS1 HGNC:HGNC:27523|Ensembl:ENSG00000259462 +283693 ACTG1P17 HGNC:HGNC:51497 +283694 OR4N4 HGNC:HGNC:15375|Ensembl:ENSG00000183706|Vega:OTTHUMG00000171739 +283698 SYNGR2P1 HGNC:HGNC:11500 +283710 LOC283710 - +283711 UBE2CP4 HGNC:HGNC:43553 +283726 SAXO2 HGNC:HGNC:33727|Ensembl:ENSG00000188659|Vega:OTTHUMG00000172646 +283731 LOC283731 Ensembl:ENSG00000248540 +283738 NTRK3-AS1 HGNC:HGNC:27532|Ensembl:ENSG00000260305 +283742 FAM98B MIM:616142|HGNC:HGNC:26773|Ensembl:ENSG00000171262|Vega:OTTHUMG00000129831 +283747 ELOCP2 HGNC:HGNC:17762 +283748 PLA2G4D MIM:612864|HGNC:HGNC:30038|Ensembl:ENSG00000159337|Vega:OTTHUMG00000172587 +283755 HERC2P3 HGNC:HGNC:4871|Ensembl:ENSG00000180229 +283761 LINC00928 HGNC:HGNC:27535 +283767 GOLGA6L1 HGNC:HGNC:37444|Ensembl:ENSG00000273976|Vega:OTTHUMG00000171928 +283768 GOLGA8G HGNC:HGNC:25328|Ensembl:ENSG00000183629 +283777 FAM169B HGNC:HGNC:26835|Ensembl:ENSG00000283597 +283788 LOC283788 - +283796 GOLGA8IP HGNC:HGNC:26660|Ensembl:ENSG00000277561 +283804 LOC283804 - +283807 FBXL22 MIM:609088|HGNC:HGNC:27537|Ensembl:ENSG00000197361|Vega:OTTHUMG00000132905 +283820 NOMO2 MIM:609158|HGNC:HGNC:22652|Ensembl:ENSG00000185164 +283847 TERB1 MIM:617332|HGNC:HGNC:26675|Ensembl:ENSG00000249961|Vega:OTTHUMG00000133562 +283848 CES4A HGNC:HGNC:26741|Ensembl:ENSG00000172824|Vega:OTTHUMG00000167866 +283849 EXOC3L1 MIM:614117|HGNC:HGNC:27540|Ensembl:ENSG00000179044|Vega:OTTHUMG00000137508 +283854 CASC22 HGNC:HGNC:50627|Ensembl:ENSG00000260887 +283856 LOC283856 Ensembl:ENSG00000246379 +283860 LINC00304 HGNC:HGNC:26713|Ensembl:ENSG00000180422 +283867 LINC00922 HGNC:HGNC:27545|Ensembl:ENSG00000261742 +283869 NPW MIM:607997|HGNC:HGNC:30509|Ensembl:ENSG00000183971 +283870 BRICD5 HGNC:HGNC:28309|Ensembl:ENSG00000182685|Vega:OTTHUMG00000128831 +283871 PGP MIM:172280|HGNC:HGNC:8909|Ensembl:ENSG00000184207|Vega:OTTHUMG00000177047 +283875 LINC00514 HGNC:HGNC:27549 +283876 LINC00921 HGNC:HGNC:26830|Ensembl:ENSG00000281005 +283887 LINC02175 HGNC:HGNC:27550|Ensembl:ENSG00000262155 +283888 IL21R-AS1 HGNC:HGNC:27551|Ensembl:ENSG00000259954 +283897 C16orf54 HGNC:HGNC:26649|Ensembl:ENSG00000185905|Vega:OTTHUMG00000132116 +283899 INO80E HGNC:HGNC:26905|Ensembl:ENSG00000169592|Vega:OTTHUMG00000132114 +283902 HCCAT5 MIM:615613|HGNC:HGNC:48612|Ensembl:ENSG00000260880 +283914 LINC01566 HGNC:HGNC:27555|Ensembl:ENSG00000259841 +283922 LOC283922 Ensembl:ENSG00000214331 +283927 NUDT7 MIM:609231|HGNC:HGNC:8054|Ensembl:ENSG00000140876|Vega:OTTHUMG00000176808 +283932 FBXL19-AS1 HGNC:HGNC:27557|Ensembl:ENSG00000260852 +283933 ZNF843 HGNC:HGNC:28710|Ensembl:ENSG00000176723|Vega:OTTHUMG00000176616 +283948 NHLRC4 HGNC:HGNC:26700|Ensembl:ENSG00000257108|Vega:OTTHUMG00000047857 +283951 C16orf91 HGNC:HGNC:27558|Ensembl:ENSG00000174109|Vega:OTTHUMG00000176551 +283953 TMEM114 MIM:611579|HGNC:HGNC:33227|Ensembl:ENSG00000232258|Vega:OTTHUMG00000172868 +283955 PKD1P2 HGNC:HGNC:30066 +283970 PDXDC2P-NPIPB14P Ensembl:ENSG00000196696 +283971 CLEC18C MIM:616573|HGNC:HGNC:28538|Ensembl:ENSG00000157335|Vega:OTTHUMG00000176982 +283981 LINC00685 HGNC:HGNC:27560 +283982 LINC00469 HGNC:HGNC:26863 +283985 FADS6 HGNC:HGNC:30459|Ensembl:ENSG00000172782|Vega:OTTHUMG00000179188 +283987 HID1 MIM:605752|HGNC:HGNC:15736|Ensembl:ENSG00000167861|Vega:OTTHUMG00000166490 +283989 TSEN54 MIM:608755|HGNC:HGNC:27561|Ensembl:ENSG00000182173|Vega:OTTHUMG00000179684 +283991 UBALD2 HGNC:HGNC:28438|Ensembl:ENSG00000185262|Vega:OTTHUMG00000132666 +283994 LINC00868 HGNC:HGNC:27562|Ensembl:ENSG00000267535 +283999 TMEM235 HGNC:HGNC:27563|Ensembl:ENSG00000204278|Vega:OTTHUMG00000170345 +284001 CCDC57 HGNC:HGNC:27564|Ensembl:ENSG00000176155|Vega:OTTHUMG00000140396 +284004 HEXDC MIM:616864|HGNC:HGNC:26307|Ensembl:ENSG00000169660|Vega:OTTHUMG00000178836 +284009 LOC284009 - +284013 VMO1 HGNC:HGNC:30387|Ensembl:ENSG00000182853|Vega:OTTHUMG00000177898 +284018 C17orf58 HGNC:HGNC:27568|Ensembl:ENSG00000186665|Vega:OTTHUMG00000179782 +284021 MILR1 HGNC:HGNC:27570|Ensembl:ENSG00000271605|Vega:OTTHUMG00000185198 +284023 LOC284023 Ensembl:ENSG00000179859|Vega:OTTHUMG00000132873 +284029 LINC00324 HGNC:HGNC:26628|Ensembl:ENSG00000178977 +284034 LINC00670 HGNC:HGNC:44338|Ensembl:ENSG00000179136 +284040 CDRT4 HGNC:HGNC:14383|Ensembl:ENSG00000239704|Vega:OTTHUMG00000059070 +284047 CCDC144B HGNC:HGNC:26704|Ensembl:ENSG00000154874 +284058 KANSL1 MIM:612452|HGNC:HGNC:24565|Ensembl:ENSG00000120071|Vega:OTTHUMG00000178026 +284064 RPL29P31 HGNC:HGNC:35944 +284067 C17orf105 HGNC:HGNC:37241|Ensembl:ENSG00000231256|Vega:OTTHUMG00000180890 +284069 FAM171A2 HGNC:HGNC:30480|Ensembl:ENSG00000161682|Vega:OTTHUMG00000132421 +284071 MEIOC MIM:616934|HGNC:HGNC:26670|Ensembl:ENSG00000180336|Vega:OTTHUMG00000153039 +284076 TTLL6 MIM:610849|HGNC:HGNC:26664|Ensembl:ENSG00000170703|Vega:OTTHUMG00000156978 +284080 PICART1 Ensembl:ENSG00000246640 +284083 C17orf47 HGNC:HGNC:26844|Ensembl:ENSG00000181013|Vega:OTTHUMG00000179244 +284085 KRT18P55 HGNC:HGNC:26874|Ensembl:ENSG00000265480 +284086 NEK8 MIM:609799|HGNC:HGNC:13387|Ensembl:ENSG00000160602|Vega:OTTHUMG00000179454 +284098 PIGW MIM:610275|HGNC:HGNC:23213|Ensembl:ENSG00000277161|Vega:OTTHUMG00000188438 +284099 C17orf78 HGNC:HGNC:26831|Ensembl:ENSG00000278505|Vega:OTTHUMG00000188467 +284100 YWHAEP7 HGNC:HGNC:49437|Ensembl:ENSG00000276715 +284106 CISD3 MIM:611933|HGNC:HGNC:27578|Ensembl:ENSG00000277972|Vega:OTTHUMG00000188500 +284110 GSDMA MIM:611218|HGNC:HGNC:13311|Ensembl:ENSG00000167914|Vega:OTTHUMG00000179522 +284111 SLC13A5 MIM:608305|HGNC:HGNC:23089|Ensembl:ENSG00000141485|Vega:OTTHUMG00000102052 +284114 TMEM102 MIM:613936|HGNC:HGNC:26722|Ensembl:ENSG00000181284|Vega:OTTHUMG00000132901 +284116 KRT42P HGNC:HGNC:27581|Ensembl:ENSG00000214514 +284119 CAVIN1 MIM:603198|HGNC:HGNC:9688|Ensembl:ENSG00000177469|Vega:OTTHUMG00000180137 +284123 FAM27E5 HGNC:HGNC:32410|Ensembl:ENSG00000178130 +284124 FLJ36000 MIM:605160|Ensembl:ENSG00000276399 +284129 SLC26A11 MIM:610117|HGNC:HGNC:14471|Ensembl:ENSG00000181045|Vega:OTTHUMG00000133419 +284131 ENDOV HGNC:HGNC:26640|Ensembl:ENSG00000173818|Vega:OTTHUMG00000164638 +284161 GDPD1 MIM:616317|HGNC:HGNC:20883|Ensembl:ENSG00000153982|Vega:OTTHUMG00000179376 +284167 POLRMTP1 HGNC:HGNC:28865 +284184 NDUFAF8 HGNC:HGNC:33551|Ensembl:ENSG00000224877|Vega:OTTHUMG00000177867 +284185 LINC00482 HGNC:HGNC:26816 +284186 TMEM105 HGNC:HGNC:26794|Ensembl:ENSG00000185332|Vega:OTTHUMG00000177905 +284191 LOC284191 - +284194 LGALS9B HGNC:HGNC:24842|Ensembl:ENSG00000170298|Vega:OTTHUMG00000130730 +284196 KRT17P6 HGNC:HGNC:50724 +284203 RNASEH1P1 HGNC:HGNC:10049 +284207 METRNL MIM:616241|HGNC:HGNC:27584|Ensembl:ENSG00000176845|Vega:OTTHUMG00000177771 +284215 DLGAP1-AS5 HGNC:HGNC:27586|Ensembl:ENSG00000261520 +284217 LAMA1 MIM:150320|HGNC:HGNC:6481|Ensembl:ENSG00000101680|Vega:OTTHUMG00000133478 +284230 RPL36AP49 HGNC:HGNC:36274 +284232 ANKRD20A9P HGNC:HGNC:42023 +284233 CYP4F35P HGNC:HGNC:39954|Ensembl:ENSG00000265787 +284240 LOC284240 - +284241 LOC284241 Ensembl:ENSG00000178412 +284252 KCTD1 MIM:613420|HGNC:HGNC:18249|Ensembl:ENSG00000134504|Vega:OTTHUMG00000131947 +284254 DYNAP HGNC:HGNC:26808|Ensembl:ENSG00000178690|Vega:OTTHUMG00000132709 +284257 BOD1L2 HGNC:HGNC:28505|Ensembl:ENSG00000228075|Vega:OTTHUMG00000180124 +284260 LINC00907 HGNC:HGNC:44327|Ensembl:ENSG00000267586 +284266 SIGLEC15 HGNC:HGNC:27596|Ensembl:ENSG00000197046|Vega:OTTHUMG00000170870 +284269 LOC284269 - +284273 ZADH2 HGNC:HGNC:28697|Ensembl:ENSG00000180011|Vega:OTTHUMG00000132858 +284274 SMIM21 HGNC:HGNC:27598|Ensembl:ENSG00000206026|Vega:OTTHUMG00000179126 +284276 LINC00908 HGNC:HGNC:27599|Ensembl:ENSG00000263812 +284288 RSL24D1P11 HGNC:HGNC:37881 +284293 HMSD MIM:612086|HGNC:HGNC:23037|Ensembl:ENSG00000221887|Vega:OTTHUMG00000060593 +284294 LINC01924 HGNC:HGNC:27600|Ensembl:ENSG00000267134 +284297 SSC5D HGNC:HGNC:26641|Ensembl:ENSG00000179954|Vega:OTTHUMG00000180855 +284306 ZNF547 HGNC:HGNC:26432|Ensembl:ENSG00000152433|Vega:OTTHUMG00000183246 +284307 ZIK1 HGNC:HGNC:33104|Ensembl:ENSG00000171649|Vega:OTTHUMG00000183468 +284309 ZNF776 HGNC:HGNC:26765|Ensembl:ENSG00000152443|Vega:OTTHUMG00000156943 +284312 ZSCAN1 HGNC:HGNC:23712|Ensembl:ENSG00000152467|Vega:OTTHUMG00000183381 +284323 ZNF780A HGNC:HGNC:27603|Ensembl:ENSG00000197782|Vega:OTTHUMG00000155119 +284325 C19orf54 HGNC:HGNC:24758|Ensembl:ENSG00000188493|Vega:OTTHUMG00000150174 +284338 PRR19 HGNC:HGNC:33728|Ensembl:ENSG00000188368|Vega:OTTHUMG00000182796 +284339 TMEM145 HGNC:HGNC:26912|Ensembl:ENSG00000167619|Vega:OTTHUMG00000177694 +284340 CXCL17 MIM:611387|HGNC:HGNC:19232|Ensembl:ENSG00000189377|Vega:OTTHUMG00000182817 +284344 LOC284344 Ensembl:ENSG00000241104 +284346 ZNF575 HGNC:HGNC:27606|Ensembl:ENSG00000176472|Vega:OTTHUMG00000182698 +284348 LYPD5 HGNC:HGNC:26397|Ensembl:ENSG00000159871|Vega:OTTHUMG00000182781 +284349 ZNF283 HGNC:HGNC:13077|Ensembl:ENSG00000167637|Vega:OTTHUMG00000182186 +284352 PPP1R37 HGNC:HGNC:27607|Ensembl:ENSG00000104866|Vega:OTTHUMG00000168143 +284353 NKPD1 HGNC:HGNC:24739 +284355 TPRX1 MIM:611166|HGNC:HGNC:32174|Ensembl:ENSG00000178928|Vega:OTTHUMG00000170628 +284358 MAMSTR MIM:610349|HGNC:HGNC:26689|Ensembl:ENSG00000176909|Vega:OTTHUMG00000183322 +284359 IZUMO1 MIM:609278|HGNC:HGNC:28539|Ensembl:ENSG00000182264|Vega:OTTHUMG00000183324 +284361 EMC10 MIM:614545|HGNC:HGNC:27609|Ensembl:ENSG00000161671|Vega:OTTHUMG00000183042 +284365 LINC01869 HGNC:HGNC:25050|Ensembl:ENSG00000180279 +284366 KLK9 MIM:605504|HGNC:HGNC:6370|Ensembl:ENSG00000213022|Ensembl:ENSG00000269741|Vega:OTTHUMG00000183087|Vega:OTTHUMG00000183088 +284367 SIGLEC17P HGNC:HGNC:15604|Ensembl:ENSG00000171101 +284369 SIGLECL1 HGNC:HGNC:26856|Ensembl:ENSG00000179213|Vega:OTTHUMG00000182881 +284370 ZNF615 HGNC:HGNC:24740|Ensembl:ENSG00000197619|Vega:OTTHUMG00000182550 +284371 ZNF841 HGNC:HGNC:27611|Ensembl:ENSG00000197608|Vega:OTTHUMG00000182558 +284379 LOC284379 Ensembl:ENSG00000268864 +284382 ACTL9 HGNC:HGNC:28494|Ensembl:ENSG00000181786|Vega:OTTHUMG00000182194 +284383 OR2Z1 HGNC:HGNC:15391|Ensembl:ENSG00000181733|Vega:OTTHUMG00000182195 +284385 ZNF561-AS1 HGNC:HGNC:27613|Ensembl:ENSG00000267106 +284390 ZNF763 HGNC:HGNC:27614|Ensembl:ENSG00000197054|Vega:OTTHUMG00000156430 +284391 ZNF844 HGNC:HGNC:25932|Ensembl:ENSG00000223547|Vega:OTTHUMG00000156405 +284393 RPL10P16 HGNC:HGNC:36882 +284395 LOC284395 Ensembl:ENSG00000264515 +284402 SCGB2B2 MIM:615063|HGNC:HGNC:27616|Ensembl:ENSG00000205209|Vega:OTTHUMG00000182463 +284403 WDR62 MIM:613583|HGNC:HGNC:24502|Ensembl:ENSG00000075702|Vega:OTTHUMG00000048139 +284406 ZFP82 HGNC:HGNC:28682|Ensembl:ENSG00000181007|Vega:OTTHUMG00000048146 +284408 ZNF790-AS1 HGNC:HGNC:27617|Ensembl:ENSG00000267254 +284412 LOC284412 - +284415 VSTM1 MIM:616804|HGNC:HGNC:29455|Ensembl:ENSG00000189068|Vega:OTTHUMG00000064906 +284417 TMEM150B MIM:617291|HGNC:HGNC:34415|Ensembl:ENSG00000180061|Vega:OTTHUMG00000180709 +284418 FAM71E2 HGNC:HGNC:25278|Ensembl:ENSG00000180043|Vega:OTTHUMG00000170357 +284422 SMIM24 HGNC:HGNC:37244|Ensembl:ENSG00000095932|Vega:OTTHUMG00000180761 +284424 MIR7-3HG HGNC:HGNC:30049|Ensembl:ENSG00000176840 +284427 SLC25A41 MIM:610822|HGNC:HGNC:28533|Ensembl:ENSG00000181240|Vega:OTTHUMG00000180851 +284428 MBD3L5 HGNC:HGNC:37204|Ensembl:ENSG00000237247|Vega:OTTHUMG00000181973 +284433 OR10H5 HGNC:HGNC:15389|Ensembl:ENSG00000172519|Vega:OTTHUMG00000182284 +284434 NWD1 MIM:616250|HGNC:HGNC:27619|Ensembl:ENSG00000188039|Vega:OTTHUMG00000164507 +284439 SLC25A42 MIM:610823|HGNC:HGNC:28380|Ensembl:ENSG00000181035|Vega:OTTHUMG00000183280 +284440 LINC00663 MIM:617117|HGNC:HGNC:28609 +284441 LOC284441 - +284443 ZNF493 HGNC:HGNC:23708|Ensembl:ENSG00000196268|Vega:OTTHUMG00000141297 +284451 ODF3L2 HGNC:HGNC:26841|Ensembl:ENSG00000181781|Vega:OTTHUMG00000180547 +284454 LOC284454 Ensembl:ENSG00000267519 +284459 HKR1 MIM:165250|HGNC:HGNC:4928|Ensembl:ENSG00000181666|Vega:OTTHUMG00000181937 +284467 FAM19A3 MIM:617497|HGNC:HGNC:21590|Ensembl:ENSG00000184599|Vega:OTTHUMG00000012020 +284485 RIIAD1 HGNC:HGNC:26686|Ensembl:ENSG00000178796|Vega:OTTHUMG00000013055 +284486 THEM5 MIM:615653|HGNC:HGNC:26755|Ensembl:ENSG00000196407|Vega:OTTHUMG00000013070 +284498 C1orf167 HGNC:HGNC:25262|Ensembl:ENSG00000215910|Vega:OTTHUMG00000002228 +284521 OR2L13 HGNC:HGNC:19578|Ensembl:ENSG00000196071|Vega:OTTHUMG00000040446 +284525 SLC9C2 HGNC:HGNC:28664|Ensembl:ENSG00000162753|Vega:OTTHUMG00000034800 +284532 OR14A16 HGNC:HGNC:15022|Ensembl:ENSG00000196772|Vega:OTTHUMG00000040199 +284541 CYP4A22 MIM:615341|HGNC:HGNC:20575|Ensembl:ENSG00000162365|Vega:OTTHUMG00000007845 +284546 C1orf185 HGNC:HGNC:28096|Ensembl:ENSG00000204006|Vega:OTTHUMG00000008084 +284551 LINC01226 HGNC:HGNC:49678 +284561 LOC284561 - +284565 NBPF15 MIM:610414|MIM:614005|HGNC:HGNC:28791|Ensembl:ENSG00000266338|Vega:OTTHUMG00000013634 +284573 LINC00303 HGNC:HGNC:26865|Ensembl:ENSG00000176754 +284576 LEMD1-AS1 HGNC:HGNC:44132|Ensembl:ENSG00000226235 +284577 LOC284577 - +284578 LOC284578 - +284581 LOC284581 - +284593 FAM41C HGNC:HGNC:27635|Ensembl:ENSG00000230368 +284600 LOC284600 - +284611 FAM102B HGNC:HGNC:27637|Ensembl:ENSG00000162636|Vega:OTTHUMG00000010967 +284612 SYPL2 HGNC:HGNC:27638|Ensembl:ENSG00000143028|Vega:OTTHUMG00000010969 +284613 CYB561D1 HGNC:HGNC:26804|Ensembl:ENSG00000174151|Vega:OTTHUMG00000011051 +284615 ANKRD34A HGNC:HGNC:27639|Ensembl:ENSG00000272031|Vega:OTTHUMG00000013740 +284618 RUSC1-AS1 HGNC:HGNC:26680 +284620 LOC284620 - +284632 LOC284632 Ensembl:ENSG00000230023 +284648 LINC01686 HGNC:HGNC:27643|Ensembl:ENSG00000261504 +284649 SMG7-AS1 HGNC:HGNC:24518|Ensembl:ENSG00000232860 +284654 RSPO1 MIM:609595|HGNC:HGNC:21679|Ensembl:ENSG00000169218|Vega:OTTHUMG00000004321 +284656 EPHA10 MIM:611123|HGNC:HGNC:19987|Ensembl:ENSG00000183317|Vega:OTTHUMG00000004325 +284661 LINC01777 HGNC:HGNC:52567|Ensembl:ENSG00000235054 +284672 PTGES3P1 HGNC:HGNC:43824 +284677 SNHG28 HGNC:HGNC:27647|Ensembl:ENSG00000188004|Vega:OTTHUMG00000035430 +284680 SPATA46 MIM:617257|HGNC:HGNC:27648|Ensembl:ENSG00000171722|Vega:OTTHUMG00000031375 +284685 LOC284685 - +284688 LINC01142 HGNC:HGNC:49456|Ensembl:ENSG00000224286 +284695 ZNF326 MIM:614601|HGNC:HGNC:14104|Ensembl:ENSG00000162664|Vega:OTTHUMG00000010675 +284697 BTBD8 HGNC:HGNC:21019|Ensembl:ENSG00000284413|Vega:OTTHUMG00000010289 +284716 RIMKLA HGNC:HGNC:28725|Ensembl:ENSG00000177181|Vega:OTTHUMG00000007335 +284723 SLC25A34 MIM:610817|HGNC:HGNC:27653|Ensembl:ENSG00000162461|Vega:OTTHUMG00000003063 +284729 ESPNP HGNC:HGNC:23285|Ensembl:ENSG00000268869 +284739 C20orf204 HGNC:HGNC:27655|Ensembl:ENSG00000196421 +284749 LINC00494 HGNC:HGNC:27657|Ensembl:ENSG00000235621 +284751 LINC01270 HGNC:HGNC:27658|Ensembl:ENSG00000203999 +284756 C20orf197 HGNC:HGNC:26601 +284757 MIR646HG HGNC:HGNC:27659|Ensembl:ENSG00000228340 +284759 SIRPB2 HGNC:HGNC:16247|Ensembl:ENSG00000196209|Vega:OTTHUMG00000031670 +284764 FTLP3 HGNC:HGNC:4000 +284788 LOC284788 Ensembl:ENSG00000204684 +284798 LOC284798 Ensembl:ENSG00000230725 +284800 FAM182A HGNC:HGNC:16222|Ensembl:ENSG00000125804 +284801 MIR663AHG HGNC:HGNC:27662|Ensembl:ENSG00000227195 +284802 FRG1BP HGNC:HGNC:15792 +284805 C20orf203 HGNC:HGNC:26592 +284821 RPL13AP7 HGNC:HGNC:23755 +284825 LINC01697 HGNC:HGNC:52485|Ensembl:ENSG00000232079 +284827 KRTAP13-4 HGNC:HGNC:18926|Ensembl:ENSG00000186971|Vega:OTTHUMG00000057770 +284835 LINC00323 HGNC:HGNC:19720|Ensembl:ENSG00000226496 +284836 LINC00319 HGNC:HGNC:19730|Ensembl:ENSG00000188660 +284837 AATBC HGNC:HGNC:51526|Ensembl:ENSG00000215458 +284865 LOC284865 Ensembl:ENSG00000249923 +284889 MIF-AS1 HGNC:HGNC:27669 +284898 LOC284898 - +284900 TTC28-AS1 HGNC:HGNC:29336|Ensembl:ENSG00000235954 +284904 SEC14L4 MIM:612825|HGNC:HGNC:20627|Ensembl:ENSG00000133488|Vega:OTTHUMG00000151258 +284912 LOC284912 - +284930 LOC284930 Ensembl:ENSG00000224271 +284933 LOC284933 Ensembl:ENSG00000281732 +284942 RPL23AP82 HGNC:HGNC:33730 +284948 SH2D6 HGNC:HGNC:30439|Ensembl:ENSG00000152292|Vega:OTTHUMG00000130176 +284950 LOC284950 - +284958 NT5DC4 HGNC:HGNC:27678|Ensembl:ENSG00000144130|Vega:OTTHUMG00000153308 +284988 RHOQP3 HGNC:HGNC:37837 +284992 CCDC150 HGNC:HGNC:26834|Ensembl:ENSG00000144395|Vega:OTTHUMG00000154475 +284996 RNF149 HGNC:HGNC:23137|Ensembl:ENSG00000163162|Vega:OTTHUMG00000130685 +284998 LINC01114 HGNC:HGNC:49245|Ensembl:ENSG00000234177 +285000 LOC285000 - +285003 MRPL36P1 HGNC:HGNC:29708 +285016 ALKAL2 HGNC:HGNC:27683|Ensembl:ENSG00000189292|Vega:OTTHUMG00000151366 +285025 CCDC141 MIM:616031|HGNC:HGNC:26821|Ensembl:ENSG00000163492|Vega:OTTHUMG00000132578 +285033 STARD7-AS1 HGNC:HGNC:40827 +285043 LOC285043 - +285045 LINC00486 HGNC:HGNC:42946|Ensembl:ENSG00000230876 +285051 STPG4 HGNC:HGNC:26850|Ensembl:ENSG00000239605|Ensembl:ENSG00000273269|Vega:OTTHUMG00000128851 +285053 RPL18AP6 HGNC:HGNC:36266 +285074 LOC285074 - +285084 LINC01305 HGNC:HGNC:27690|Ensembl:ENSG00000231453 +285093 RTP5 HGNC:HGNC:26585|Ensembl:ENSG00000188011|Vega:OTTHUMG00000151341 +285095 LOC285095 Ensembl:ENSG00000216921|Vega:OTTHUMG00000151374 +285097 LOC285097 - +285103 MED15P9 HGNC:HGNC:44130|Ensembl:ENSG00000223760 +285116 AHCTF1P1 HGNC:HGNC:24620 +285126 DNAJC5G MIM:613946|HGNC:HGNC:24844|Ensembl:ENSG00000163793|Vega:OTTHUMG00000097079 +285141 ERICH2 HGNC:HGNC:44395|Ensembl:ENSG00000204334|Vega:OTTHUMG00000154074 +285148 IAH1 HGNC:HGNC:27696|Ensembl:ENSG00000134330|Vega:OTTHUMG00000159076 +285150 FLJ33534 Ensembl:ENSG00000145063 +285154 CYP1B1-AS1 HGNC:HGNC:28543|Ensembl:ENSG00000232973 +285172 FAM126B HGNC:HGNC:28593|Ensembl:ENSG00000155744|Vega:OTTHUMG00000132823 +285175 UNC80 MIM:612636|HGNC:HGNC:26582|Ensembl:ENSG00000144406|Vega:OTTHUMG00000132963 +285176 RPL10P6 HGNC:HGNC:52343 +285180 RUFY4 HGNC:HGNC:24804|Ensembl:ENSG00000188282|Vega:OTTHUMG00000155235 +285189 PLGLA MIM:612212|HGNC:HGNC:9074|Ensembl:ENSG00000240935 +285190 RGPD4 MIM:612707|HGNC:HGNC:32417|Ensembl:ENSG00000196862|Vega:OTTHUMG00000153208 +285191 LOC285191 - +285193 DUSP28 HGNC:HGNC:33237|Ensembl:ENSG00000188542|Vega:OTTHUMG00000152310 +285194 TUSC7 MIM:616057|HGNC:HGNC:27701 +285195 SLC9A9 MIM:608396|HGNC:HGNC:20653|Ensembl:ENSG00000181804|Vega:OTTHUMG00000159373 +285203 EOGT MIM:614789|HGNC:HGNC:28526|Ensembl:ENSG00000163378|Vega:OTTHUMG00000156279 +285205 LINC00636 HGNC:HGNC:27702|Ensembl:ENSG00000240423 +285220 EPHA6 MIM:600066|HGNC:HGNC:19296|Ensembl:ENSG00000080224|Vega:OTTHUMG00000159208 +285224 DNAJB8-AS1 HGNC:HGNC:41029|Ensembl:ENSG00000242049 +285231 FBXW12 MIM:609075|HGNC:HGNC:20729|Ensembl:ENSG00000164049|Vega:OTTHUMG00000133530 +285232 LOC285232 - +285237 C3orf38 HGNC:HGNC:28384|Ensembl:ENSG00000179021|Vega:OTTHUMG00000155752 +285242 HTR3E MIM:610123|HGNC:HGNC:24005|Ensembl:ENSG00000186038|Vega:OTTHUMG00000156857 +285260 RPL31P18 HGNC:HGNC:35833 +285266 ENTPD3-AS1 HGNC:HGNC:26710|Ensembl:ENSG00000223797 +285267 ZNF619 HGNC:HGNC:26910|Ensembl:ENSG00000177873|Vega:OTTHUMG00000131391 +285268 ZNF621 HGNC:HGNC:24787|Ensembl:ENSG00000172888|Vega:OTTHUMG00000131389 +285282 RABL3 HGNC:HGNC:18072|Ensembl:ENSG00000144840|Vega:OTTHUMG00000159668 +285286 LINC00877 HGNC:HGNC:27706|Ensembl:ENSG00000241163 +285296 UNC93B3 HGNC:HGNC:13483 +285303 LOC285303 - +285311 C3orf56 HGNC:HGNC:32481 +285313 IGSF10 MIM:617351|HGNC:HGNC:26384|Ensembl:ENSG00000152580|Vega:OTTHUMG00000159856 +285314 PABPC1P10 MIM:173865|HGNC:HGNC:37992 +285315 C3orf33 HGNC:HGNC:26434|Ensembl:ENSG00000174928|Vega:OTTHUMG00000158496 +285326 LINC00692 HGNC:HGNC:27708|Ensembl:ENSG00000230891 +285329 UBQLN4P1 HGNC:HGNC:31133 +285331 CCDC66 HGNC:HGNC:27709|Ensembl:ENSG00000180376|Vega:OTTHUMG00000155748 +285335 SLC9C1 MIM:612738|HGNC:HGNC:31401|Ensembl:ENSG00000172139|Vega:OTTHUMG00000159245 +285343 TCAIM HGNC:HGNC:25241|Ensembl:ENSG00000179152|Vega:OTTHUMG00000133049 +285346 ZNF852 HGNC:HGNC:27713|Ensembl:ENSG00000178917 +285349 ZNF660 HGNC:HGNC:26720|Ensembl:ENSG00000144792|Vega:OTTHUMG00000133097 +285352 KIF9-AS1 HGNC:HGNC:26822 +285359 PDCL3P4 HGNC:HGNC:44505 +285362 SUMF1 MIM:607939|HGNC:HGNC:20376|Ensembl:ENSG00000144455|Vega:OTTHUMG00000090269 +285367 RPUSD3 HGNC:HGNC:28437|Ensembl:ENSG00000156990|Vega:OTTHUMG00000128441 +285368 PRRT3 HGNC:HGNC:26591|Ensembl:ENSG00000163704|Vega:OTTHUMG00000155285 +285370 LINC00606 HGNC:HGNC:43931|Ensembl:ENSG00000226567 +285375 LINC00620 HGNC:HGNC:44223|Ensembl:ENSG00000224514 +285381 DPH3 MIM:608959|HGNC:HGNC:27717|Ensembl:ENSG00000154813|Vega:OTTHUMG00000129866 +285382 C3orf70 HGNC:HGNC:33731|Ensembl:ENSG00000187068|Vega:OTTHUMG00000156696 +285386 TPRG1 HGNC:HGNC:24759|Ensembl:ENSG00000188001|Vega:OTTHUMG00000156321 +285389 LINC02028 HGNC:HGNC:27718|Ensembl:ENSG00000230102 +285401 LINC00698 HGNC:HGNC:27720|Ensembl:ENSG00000244342 +285407 ALG1L9P HGNC:HGNC:44378|Ensembl:ENSG00000248671 +285412 TOX4P1 HGNC:HGNC:44009 +285415 MRPL42P1 HGNC:HGNC:29710 +285419 LINC01091 HGNC:HGNC:27721|Ensembl:ENSG00000249464 +285422 LOC285422 - +285423 IQCM HGNC:HGNC:53443|Ensembl:ENSG00000234828|Vega:OTTHUMG00000161394 +285429 DCAF4L1 HGNC:HGNC:27723|Ensembl:ENSG00000182308|Vega:OTTHUMG00000160527 +285440 CYP4V2 MIM:608614|HGNC:HGNC:23198|Ensembl:ENSG00000145476|Vega:OTTHUMG00000160379 +285441 F11-AS1 HGNC:HGNC:27725|Ensembl:ENSG00000251165 +285442 LOC285442 - +285453 LOC285453 - +285456 RPL34-AS1 HGNC:HGNC:26749|Ensembl:ENSG00000234492 +285463 CTBP1-AS HGNC:HGNC:48337|Ensembl:ENSG00000280927 +285464 CRIPAK MIM:610203|HGNC:HGNC:26619|Ensembl:ENSG00000179979|Vega:OTTHUMG00000121131 +285484 LINC02495 HGNC:HGNC:27728 +285489 DOK7 MIM:610285|HGNC:HGNC:26594|Ensembl:ENSG00000175920|Vega:OTTHUMG00000122087 +285492 LINC00955 HGNC:HGNC:26644 +285498 RNF212 MIM:612041|HGNC:HGNC:27729|Ensembl:ENSG00000178222|Vega:OTTHUMG00000118997 +285500 LOC285500 - +285501 LINC01098 HGNC:HGNC:27731|Ensembl:ENSG00000231171 +285505 LOC285505 - +285512 FAM13A-AS1 MIM:613300|HGNC:HGNC:19370|Ensembl:ENSG00000248019 +285513 GPRIN3 MIM:611241|HGNC:HGNC:27733|Ensembl:ENSG00000185477|Vega:OTTHUMG00000161044 +285521 COX18 MIM:610428|HGNC:HGNC:26801|Ensembl:ENSG00000163626|Vega:OTTHUMG00000129917 +285525 YIPF7 HGNC:HGNC:26825|Ensembl:ENSG00000177752|Vega:OTTHUMG00000160467 +285527 FRYL HGNC:HGNC:29127|Ensembl:ENSG00000075539|Vega:OTTHUMG00000160608 +285533 RNF175 HGNC:HGNC:27735|Ensembl:ENSG00000145428|Vega:OTTHUMG00000161557 +285540 SEPSECS-AS1 HGNC:HGNC:27737 +285547 LINC01097 HGNC:HGNC:27738|Ensembl:ENSG00000281202 +285548 LINC01096 HGNC:HGNC:27739 +285550 FAM200B HGNC:HGNC:27740|Ensembl:ENSG00000237765|Vega:OTTHUMG00000160279 +285555 STPG2 HGNC:HGNC:28712|Ensembl:ENSG00000163116|Vega:OTTHUMG00000131009 +285556 LOC285556 Ensembl:ENSG00000248713|Vega:OTTHUMG00000161583 +285577 LINC01019 HGNC:HGNC:27742|Ensembl:ENSG00000248118 +285588 EFCAB9 HGNC:HGNC:34530|Ensembl:ENSG00000214360|Vega:OTTHUMG00000163271 +285590 SH3PXD2B MIM:613293|HGNC:HGNC:29242|Ensembl:ENSG00000174705|Vega:OTTHUMG00000163280 +285591 LOC285591 - +285593 LOC285593 Ensembl:ENSG00000253955 +285596 FAM153A HGNC:HGNC:29940|Ensembl:ENSG00000170074|Vega:OTTHUMG00000163394 +285598 ARL10 HGNC:HGNC:22042|Ensembl:ENSG00000175414|Vega:OTTHUMG00000130655 +285600 KIAA0825 MIM:617266|HGNC:HGNC:28532|Ensembl:ENSG00000185261|Vega:OTTHUMG00000131331 +285601 GPR150 HGNC:HGNC:23628|Ensembl:ENSG00000178015|Vega:OTTHUMG00000121170 +285605 DTWD2 HGNC:HGNC:19334|Ensembl:ENSG00000169570|Vega:OTTHUMG00000162956 +285613 RELL2 MIM:611213|HGNC:HGNC:26902|Ensembl:ENSG00000164620|Vega:OTTHUMG00000129612 +285622 NBPF22P HGNC:HGNC:28731 +285626 LOC285626 Ensembl:ENSG00000249738 +285627 LINC01845 HGNC:HGNC:27747|Ensembl:ENSG00000253298 +285629 LINC02159 HGNC:HGNC:27749|Ensembl:ENSG00000253417 +285634 INTS6P1 HGNC:HGNC:43921 +285636 C5orf51 HGNC:HGNC:27750|Ensembl:ENSG00000205765|Vega:OTTHUMG00000162084 +285638 LOC285638 - +285641 SLC36A3 MIM:608332|HGNC:HGNC:19659|Ensembl:ENSG00000186334|Vega:OTTHUMG00000130128 +285643 KIF4B MIM:609184|HGNC:HGNC:6322|Ensembl:ENSG00000226650|Vega:OTTHUMG00000164143 +285647 SUDS3P1 HGNC:HGNC:44000 +285659 OR2V2 HGNC:HGNC:15341|Ensembl:ENSG00000182613|Vega:OTTHUMG00000130933 +285668 C5orf64 HGNC:HGNC:26744|Ensembl:ENSG00000178722 +285671 RNF180 MIM:616015|HGNC:HGNC:27752|Ensembl:ENSG00000164197|Vega:OTTHUMG00000162278 +285672 SREK1IP1 HGNC:HGNC:26716|Ensembl:ENSG00000153006|Vega:OTTHUMG00000162291 +285676 ZNF454 HGNC:HGNC:21200|Ensembl:ENSG00000178187|Vega:OTTHUMG00000130891 +285679 C5orf60 HGNC:HGNC:27753|Ensembl:ENSG00000204661 +285692 LINC02112 HGNC:HGNC:27756|Ensembl:ENSG00000249781 +285696 LOC285696 Ensembl:ENSG00000215196 +285697 LOC285697 - +285704 RGMB MIM:612687|HGNC:HGNC:26896|Ensembl:ENSG00000174136|Vega:OTTHUMG00000162745 +285706 LOC285706 - +285708 LINC00491 HGNC:HGNC:43428 +285735 LINC00326 HGNC:HGNC:41926 +285737 CCRL1P1 HGNC:HGNC:21142 +285740 PHACTR2-AS1 HGNC:HGNC:40943|Ensembl:ENSG00000235740 +285741 TPT1P4 HGNC:HGNC:49298 +285753 CEP57L1 HGNC:HGNC:21561|Ensembl:ENSG00000183137|Vega:OTTHUMG00000015336 +285755 PPIL6 HGNC:HGNC:21557|Ensembl:ENSG00000185250|Vega:OTTHUMG00000036593 +285758 LINC01268 HGNC:HGNC:50323|Ensembl:ENSG00000227502 +285759 FLJ34503 Ensembl:ENSG00000175967 +285761 DCBLD1 HGNC:HGNC:21479|Ensembl:ENSG00000164465|Vega:OTTHUMG00000015455 +285762 LOC285762 - +285766 LOC285766 Ensembl:ENSG00000263667 +285768 LINC01622 HGNC:HGNC:27768 +285780 LY86-AS1 HGNC:HGNC:26593|Ensembl:ENSG00000216863 +285782 CAGE1 MIM:608304|HGNC:HGNC:21622|Ensembl:ENSG00000164304|Vega:OTTHUMG00000014200 +285785 RPL39P3 HGNC:HGNC:21383 +285796 PACRG-AS1 HGNC:HGNC:27772|Ensembl:ENSG00000281692 +285800 PRR18 HGNC:HGNC:28574|Ensembl:ENSG00000176381|Vega:OTTHUMG00000167034 +285804 LOC285804 Ensembl:ENSG00000271820 +285819 LOC285819 - +285829 SUMO2P1 HGNC:HGNC:13985 +285830 HLA-F-AS1 HGNC:HGNC:26645|Ensembl:ENSG00000214922 +285834 HCG22 MIM:613918|HGNC:HGNC:27780|Ensembl:ENSG00000228789 +285847 LOC285847 - +285848 PNPLA1 MIM:612121|HGNC:HGNC:21246|Ensembl:ENSG00000180316|Vega:OTTHUMG00000014590 +285849 COX6A1P2 HGNC:HGNC:35239 +285852 TREML4 MIM:614664|HGNC:HGNC:30807|Ensembl:ENSG00000188056|Vega:OTTHUMG00000016408 +285855 RPL7L1 MIM:617417|HGNC:HGNC:21370|Ensembl:ENSG00000146223|Vega:OTTHUMG00000014710 +285857 LINC02537 HGNC:HGNC:27784 +285872 THAP5P1 HGNC:HGNC:22340 +285877 POM121L12 HGNC:HGNC:25369|Ensembl:ENSG00000221900|Vega:OTTHUMG00000155995 +285878 VSTM2A-OT1 HGNC:HGNC:50770|Ensembl:ENSG00000224223 +285888 CNPY1 MIM:612493|HGNC:HGNC:27786|Ensembl:ENSG00000146910|Vega:OTTHUMG00000151353 +285889 LOC285889 Ensembl:ENSG00000233878 +285893 ARAFP3 HGNC:HGNC:35474 +285900 RPL6P20 HGNC:HGNC:36543 +285905 INTS4P1 HGNC:HGNC:21925|Ensembl:ENSG00000164669 +285908 LINC00174 HGNC:HGNC:27788|Ensembl:ENSG00000179406 +285941 C7orf71 HGNC:HGNC:22364 +285943 HOXA-AS2 MIM:616068|HGNC:HGNC:43745 +285954 INHBA-AS1 HGNC:HGNC:40303|Ensembl:ENSG00000224116 +285955 SPDYE1 HGNC:HGNC:16408|Ensembl:ENSG00000136206|Vega:OTTHUMG00000128985 +285958 SNHG15 HGNC:HGNC:27797|Ensembl:ENSG00000232956 +285961 SEPT7P9 HGNC:HGNC:30810 +285962 WEE2-AS1 HGNC:HGNC:48669|Ensembl:ENSG00000228775 +285965 EPHA1-AS1 HGNC:HGNC:27799|Ensembl:ENSG00000229153 +285966 TCAF2 MIM:616252|HGNC:HGNC:26878|Ensembl:ENSG00000170379|Vega:OTTHUMG00000153232 +285971 ZNF775 HGNC:HGNC:28501|Ensembl:ENSG00000196456|Vega:OTTHUMG00000191597 +285972 LINC00996 HGNC:HGNC:27800|Ensembl:ENSG00000242258 +285973 ATG9B MIM:612205|HGNC:HGNC:21899|Ensembl:ENSG00000181652|Vega:OTTHUMG00000158634 +285987 DLX6-AS1 HGNC:HGNC:37151 +285989 ZNF789 HGNC:HGNC:27801|Ensembl:ENSG00000198556|Vega:OTTHUMG00000154601 +286002 SLC26A4-AS1 HGNC:HGNC:22385 +286006 LSMEM1 HGNC:HGNC:22036|Ensembl:ENSG00000181016|Vega:OTTHUMG00000155190 +286016 TPI1P2 HGNC:HGNC:38069|Ensembl:ENSG00000230359 +286023 FLJ40288 Ensembl:ENSG00000183470 +286042 FAM86B3P HGNC:HGNC:44371|Ensembl:ENSG00000173295 +286043 MRPS18CP2 HGNC:HGNC:29743 +286046 XKR6 HGNC:HGNC:27806|Ensembl:ENSG00000171044|Vega:OTTHUMG00000129351 +286053 NSMCE2 MIM:617246|HGNC:HGNC:26513|Ensembl:ENSG00000156831|Vega:OTTHUMG00000164993 +286059 LOC286059 Ensembl:ENSG00000246130 +286065 MAPK6PS4 HGNC:HGNC:18456 +286075 ZNF707 HGNC:HGNC:27815|Ensembl:ENSG00000181135|Vega:OTTHUMG00000165146 +286076 BREA2 - +286077 FAM83H MIM:611927|HGNC:HGNC:24797|Ensembl:ENSG00000180921|Vega:OTTHUMG00000133559 +286083 LOC286083 Ensembl:ENSG00000275427 +286094 LINC01591 HGNC:HGNC:27819|Ensembl:ENSG00000254083 +286097 MICU3 MIM:610633|HGNC:HGNC:27820|Ensembl:ENSG00000155970|Vega:OTTHUMG00000096965 +286101 ZNF252P HGNC:HGNC:13046 +286102 TMED10P1 HGNC:HGNC:30754 +286103 ZNF252P-AS1 HGNC:HGNC:27821|Ensembl:ENSG00000255559 +286114 LINC02153 HGNC:HGNC:27823|Ensembl:ENSG00000253199 +286122 C8orf31 HGNC:HGNC:26731|Ensembl:ENSG00000177335 +286128 ZFP41 HGNC:HGNC:26786|Ensembl:ENSG00000181638|Ensembl:ENSG00000264668|Vega:OTTHUMG00000164951|Vega:OTTHUMG00000179773 +286133 SCARA5 MIM:611306|HGNC:HGNC:28701|Ensembl:ENSG00000168079|Vega:OTTHUMG00000132172 +286135 LINC02209 HGNC:HGNC:27827|Ensembl:ENSG00000253279 +286140 RNF5P1 HGNC:HGNC:31053 +286144 TRIQK HGNC:HGNC:27828|Ensembl:ENSG00000205133|Vega:OTTHUMG00000164162 +286148 DPY19L4 MIM:613895|HGNC:HGNC:27829|Ensembl:ENSG00000156162|Vega:OTTHUMG00000164589 +286150 RPS2P33 HGNC:HGNC:35549 +286151 FBXO43 MIM:609110|HGNC:HGNC:28521|Ensembl:ENSG00000156509|Vega:OTTHUMG00000164803 +286156 MAPK6PS5 HGNC:HGNC:18979 +286157 PCBP2P2 HGNC:HGNC:8650 +286177 LOC286177 Ensembl:ENSG00000253614 +286178 LOC286178 Ensembl:ENSG00000254139 +286183 NKAIN3 MIM:612872|HGNC:HGNC:26829|Ensembl:ENSG00000185942|Vega:OTTHUMG00000164361 +286184 LINC01289 HGNC:HGNC:50354|Ensembl:ENSG00000253734 +286186 LINC01299 HGNC:HGNC:27839|Ensembl:ENSG00000254081 +286187 PPP1R42 HGNC:HGNC:33732|Ensembl:ENSG00000178125|Vega:OTTHUMG00000164745 +286189 C8orf34-AS1 HGNC:HGNC:27840|Ensembl:ENSG00000248801 +286190 LACTB2-AS1 HGNC:HGNC:27841|Ensembl:ENSG00000246366 +286204 CRB2 MIM:609720|HGNC:HGNC:18688|Ensembl:ENSG00000148204|Vega:OTTHUMG00000020638 +286205 SCAI HGNC:HGNC:26709|Ensembl:ENSG00000173611|Vega:OTTHUMG00000020667 +286207 CFAP157 HGNC:HGNC:27843|Ensembl:ENSG00000160401|Vega:OTTHUMG00000020709 +286223 C9orf47 HGNC:HGNC:23669|Ensembl:ENSG00000186354|Vega:OTTHUMG00000020172 +286234 SPATA31E1 HGNC:HGNC:26672|Ensembl:ENSG00000177992|Vega:OTTHUMG00000020157 +286238 LOC286238 Ensembl:ENSG00000228189 +286239 ME2P1 HGNC:HGNC:49809 +286256 LCN12 MIM:612905|HGNC:HGNC:28733|Ensembl:ENSG00000184925|Vega:OTTHUMG00000020968 +286257 PAXX MIM:616315|HGNC:HGNC:27849|Ensembl:ENSG00000148362|Vega:OTTHUMG00000020971 +286262 TPRN MIM:613354|HGNC:HGNC:26894|Ensembl:ENSG00000176058|Vega:OTTHUMG00000020984 +286297 LOC286297 - +286310 LCN1P1 HGNC:HGNC:23412 +286319 TUSC1 MIM:610529|HGNC:HGNC:31010|Ensembl:ENSG00000198680|Vega:OTTHUMG00000159591 +286333 FAM225A HGNC:HGNC:27855|Ensembl:ENSG00000231528 +286336 FAM78A HGNC:HGNC:25465|Ensembl:ENSG00000126882|Vega:OTTHUMG00000020821 +286343 LURAP1L MIM:616130|HGNC:HGNC:31452|Ensembl:ENSG00000153714|Vega:OTTHUMG00000019557 +286348 RPL7P33 HGNC:HGNC:35937 +286359 LOC286359 - +286362 OR13C9 HGNC:HGNC:15104|Ensembl:ENSG00000136839|Vega:OTTHUMG00000020416 +286365 OR13D1 HGNC:HGNC:14695|Ensembl:ENSG00000179055|Vega:OTTHUMG00000020412 +286370 MIR4290HG HGNC:HGNC:27861|Ensembl:ENSG00000227555 +286380 FOXD4L3 MIM:611086|HGNC:HGNC:18523|Ensembl:ENSG00000187559|Vega:OTTHUMG00000019959 +286410 ATP11C MIM:300516|HGNC:HGNC:13554|Ensembl:ENSG00000101974|Vega:OTTHUMG00000022538 +286411 LINC00632 HGNC:HGNC:27865|Ensembl:ENSG00000203930 +286423 MRRFP1 HGNC:HGNC:35238 +286430 NLRP2B HGNC:HGNC:29887|Ensembl:ENSG00000215174|Vega:OTTHUMG00000021686 +286436 H2BFM HGNC:HGNC:27867|Ensembl:ENSG00000101812|Vega:OTTHUMG00000022122 +286437 LOC286437 - +286442 LINC01281 HGNC:HGNC:50337|Ensembl:ENSG00000235304 +286444 RPS2P55 HGNC:HGNC:36140 +286451 YIPF6 MIM:300996|HGNC:HGNC:28304|Ensembl:ENSG00000181704|Vega:OTTHUMG00000021745 +286453 LOC286453 - +286456 LOC286456 - +286460 FAM3C2 HGNC:HGNC:34501 +286464 CFAP47 HGNC:HGNC:26708|Ensembl:ENSG00000165164|Vega:OTTHUMG00000021351 +286467 FIRRE MIM:300999|HGNC:HGNC:49627|Ensembl:ENSG00000213468 +286472 RAC1P4 HGNC:HGNC:31113 +286480 UBE2E4P HGNC:HGNC:32199 +286494 BRAFP1 MIM:300956|HGNC:HGNC:18615 +286495 TTC3P1 HGNC:HGNC:23318 +286499 FAM133A HGNC:HGNC:26748|Ensembl:ENSG00000179083|Vega:OTTHUMG00000021975 +286512 EIF4A2P4 HGNC:HGNC:45101 +286514 MAGEB18 HGNC:HGNC:28515|Ensembl:ENSG00000176774|Vega:OTTHUMG00000021282 +286527 TMSB15B HGNC:HGNC:28612|Ensembl:ENSG00000158427|Vega:OTTHUMG00000022117 +286528 SSU72P1 HGNC:HGNC:43620 +286530 P2RY8 MIM:300525|HGNC:HGNC:15524|Ensembl:ENSG00000182162|Vega:OTTHUMG00000021060 +286544 MXRA5Y HGNC:HGNC:23932 +286550 CYCSP46 HGNC:HGNC:23941 +286554 BCORP1 HGNC:HGNC:23953|Ensembl:ENSG00000215580 +286555 TBL1YP1 HGNC:HGNC:23979 +286556 CDY3P HGNC:HGNC:23849 +286557 RBMY1A3P HGNC:HGNC:18849 +286568 RPL41P6 HGNC:HGNC:37655 +286570 RPL41P7 HGNC:HGNC:37656 +286573 TPTE2P4 HGNC:HGNC:38077 +286676 ILDR1 MIM:609739|HGNC:HGNC:28741|Ensembl:ENSG00000145103|Vega:OTTHUMG00000159481 +286749 STON1-GTF2A1L HGNC:HGNC:30651|Ensembl:ENSG00000068781|Vega:OTTHUMG00000152037 +286751 OTSC4 MIM:611571|HGNC:HGNC:19981 +286753 TUSC5 MIM:612211|HGNC:HGNC:29592|Ensembl:ENSG00000184811|Vega:OTTHUMG00000132196 +286754 LEFTY3 - +286826 LIN9 MIM:609375|HGNC:HGNC:30830|Ensembl:ENSG00000183814|Vega:OTTHUMG00000037557 +286827 TRIM59 MIM:616148|HGNC:HGNC:30834|Ensembl:ENSG00000213186|Vega:OTTHUMG00000159034 +286828 CSN1S2AP HGNC:HGNC:20230|Ensembl:ENSG00000234124 +286887 KRT6C MIM:612315|HGNC:HGNC:20406|Ensembl:ENSG00000170465|Vega:OTTHUMG00000169596 +286967 FAM223B HGNC:HGNC:34048|Ensembl:ENSG00000272681 +287015 TRIM42 HGNC:HGNC:19014|Ensembl:ENSG00000155890|Vega:OTTHUMG00000160170 +317648 NOP14-AS1 HGNC:HGNC:20205|Ensembl:ENSG00000249673 +317649 EIF4E3 MIM:609896|HGNC:HGNC:31837|Ensembl:ENSG00000163412|Vega:OTTHUMG00000158797 +317662 FAM149B1 HGNC:HGNC:29162|Ensembl:ENSG00000138286|Vega:OTTHUMG00000067794 +317664 DFNA49 MIM:608372|HGNC:HGNC:18820 +317668 MCDR3 MIM:608850|HGNC:HGNC:20206 +317669 IBD9 MIM:608448|HGNC:HGNC:20236 +317671 RFESD HGNC:HGNC:29587|Ensembl:ENSG00000175449|Vega:OTTHUMG00000121168 +317682 OTSC5 MIM:608787|HGNC:HGNC:20238 +317684 MAPK6PS3 HGNC:HGNC:18977 +317685 NYS4 MIM:193003|HGNC:HGNC:19188 +317686 MAPK6PS1 HGNC:HGNC:18980 +317687 BANF1P1 HGNC:HGNC:20252 +317691 VN1R9P HGNC:HGNC:20257 +317701 VN1R2 HGNC:HGNC:19872|Ensembl:ENSG00000196131|Vega:OTTHUMG00000182906 +317702 VN1R3 HGNC:HGNC:19867|Vega:OTTHUMG00000176634 +317703 VN1R4 HGNC:HGNC:19871|Ensembl:ENSG00000228567|Vega:OTTHUMG00000182907 +317705 VN1R5 HGNC:HGNC:19870|Ensembl:ENSG00000197617 +317714 DYT15 MIM:607488|HGNC:HGNC:31376 +317716 BPIFA4P MIM:607627|HGNC:HGNC:20469|Ensembl:ENSG00000183566 +317718 DFNA37 HGNC:HGNC:18545 +317719 KLHL10 MIM:608778|HGNC:HGNC:18829|Ensembl:ENSG00000161594|Vega:OTTHUMG00000152510 +317726 HMGN2P2 HGNC:HGNC:20016 +317727 LOC317727 - +317729 BLZF2P HGNC:HGNC:20049 +317730 C14orf99 - +317749 DHRS4L2 MIM:615196|HGNC:HGNC:19731|Ensembl:ENSG00000187630|Vega:OTTHUMG00000028778 +317751 MESTIT1 MIM:607794|HGNC:HGNC:17991 +317753 PSMD12P HGNC:HGNC:30153 +317754 POTED MIM:607549|HGNC:HGNC:23822|Ensembl:ENSG00000166351|Vega:OTTHUMG00000074197 +317760 ADAM20P1 HGNC:HGNC:20102|Ensembl:ENSG00000259158 +317761 C14orf39 MIM:617307|HGNC:HGNC:19849|Ensembl:ENSG00000179008|Vega:OTTHUMG00000140332 +317762 CCDC85C HGNC:HGNC:35459|Ensembl:ENSG00000205476|Vega:OTTHUMG00000171506 +317767 SCOCP1 HGNC:HGNC:20339 +317768 HOMER2P1 HGNC:HGNC:20336 +317769 HOMER2P2 HGNC:HGNC:20334 +317772 HIST2H2AB MIM:615014|HGNC:HGNC:20508|Ensembl:ENSG00000184270|Vega:OTTHUMG00000012085 +317773 MGR6 MIM:607516 +317774 SEPT7P1 HGNC:HGNC:19926 +317775 CHORDC2P HGNC:HGNC:20050 +317778 SYF2P1 HGNC:HGNC:19925 +317780 CKS1BP1 HGNC:HGNC:20004 +317781 DDX51 HGNC:HGNC:20082|Ensembl:ENSG00000185163|Vega:OTTHUMG00000168254 +317782 CELIAC2 MIM:609754|HGNC:HGNC:19378 +317784 COILP1 HGNC:HGNC:19927 +319085 ITPK1-AS1 HGNC:HGNC:20132|Ensembl:ENSG00000258730 +319087 COX5AP2 HGNC:HGNC:20005 +319089 TTC6 HGNC:HGNC:19739|Ensembl:ENSG00000139865|Vega:OTTHUMG00000157369 +319090 OTSC6 HGNC:HGNC:20375 +319093 RHOQP1 HGNC:HGNC:20003 +319098 COX7A2P1 HGNC:HGNC:20006 +319099 DDX18P1 HGNC:HGNC:20007 +319100 TAAR6 MIM:608923|HGNC:HGNC:20978|Ensembl:ENSG00000146383|Vega:OTTHUMG00000015579 +319101 KRT73 MIM:608247|HGNC:HGNC:28928|Ensembl:ENSG00000186049|Vega:OTTHUMG00000169746 +319102 ARHGAP16P HGNC:HGNC:19921 +319103 SNORD8 HGNC:HGNC:20159|Ensembl:ENSG00000200785 +319111 DNAJC8P1 HGNC:HGNC:19928 +319112 EEF1A1P2 HGNC:HGNC:20008 +319114 ENSAP2 HGNC:HGNC:20011 +319115 EIF2S2P1 HGNC:HGNC:20009 +319116 ATP6V1G1P1 HGNC:HGNC:19816 +319117 EIF3LP1 HGNC:HGNC:20010 +319118 EIF4BP1 HGNC:HGNC:19929 +319119 ATP5G2P2 HGNC:HGNC:19672 +319120 YWHAZP1 HGNC:HGNC:19938 +319121 YWHAQP1 HGNC:HGNC:19937 +319122 UNGP3 HGNC:HGNC:20036 +319123 ZFP64P1 HGNC:HGNC:19820 +319127 NARSP1 HGNC:HGNC:19933 +319128 PPIAP6 HGNC:HGNC:20028 +319129 RPSAP5 HGNC:HGNC:20139 +319130 HMGB1P14 HGNC:HGNC:20014 +319131 HMGN1P1 HGNC:HGNC:20015 +319132 HMGN2P1 HGNC:HGNC:19930 +319133 HNRNPCP1 HGNC:HGNC:20017 +319134 HNRNPUP1 HGNC:HGNC:19931 +319135 RPL10AP1 HGNC:HGNC:19813 +319136 ATP5G1P1 HGNC:HGNC:19815 +319137 ATP5G1P2 HGNC:HGNC:19817 +319138 BNIP3P1 HGNC:HGNC:19922 +319139 SNORD56B HGNC:HGNC:19771|Ensembl:ENSG00000207444 +319140 GCATP1 HGNC:HGNC:20013 +319142 RPL12P5 HGNC:HGNC:19669 +319143 RPL21P10 HGNC:HGNC:19795 +319144 RPL21P13 HGNC:HGNC:19812 +319145 RPL21P8 HGNC:HGNC:19779 +326105 UBE2CP1 HGNC:HGNC:19670 +326106 TUBBP3 HGNC:HGNC:18192 +326107 STK16P1 HGNC:HGNC:19283 +326268 ABI1P1 HGNC:HGNC:20035 +326269 SRMP2 HGNC:HGNC:20034 +326272 SNRPGP1 HGNC:HGNC:20033 +326275 RPL12P7 HGNC:HGNC:19782 +326276 SF3B4P1 HGNC:HGNC:19821 +326277 SETP2 HGNC:HGNC:20032 +326278 RPL13AP2 HGNC:HGNC:19675 +326279 RPL15P2 HGNC:HGNC:19803 +326286 RPL17P3 HGNC:HGNC:19796 +326288 RPL17P4 HGNC:HGNC:19811 +326289 RPL18AP1 HGNC:HGNC:19778 +326291 RPL18P1 HGNC:HGNC:19673 +326292 RPL22P2 HGNC:HGNC:19794 +326293 RPL23AP10 HGNC:HGNC:19804 +326294 RPL23AP11 HGNC:HGNC:19808 +326295 EIF4EBP1P1 HGNC:HGNC:20160 +326296 HSBP1P1 HGNC:HGNC:20053 +326297 RPL26P2 HGNC:HGNC:19773 +326298 RPL26P3 HGNC:HGNC:19776 +326299 RPL27P1 HGNC:HGNC:19668 +326300 HSPE1P2 HGNC:HGNC:20052 +326301 RPL36AP2 HGNC:HGNC:19777 +326302 NEK2P1 HGNC:HGNC:19272 +326303 RPL36P3 HGNC:HGNC:19786 +326304 RPL36AP4 HGNC:HGNC:19802 +326305 MOCS3P1 HGNC:HGNC:20021 +326306 RPL39P2 HGNC:HGNC:19774 +326307 RPL3P4 HGNC:HGNC:19805 +326308 RPL41P4 HGNC:HGNC:19788 +326309 RPL7AP5 HGNC:HGNC:19781 +326310 RPL7AP6 HGNC:HGNC:19785 +326311 RPL9P6 HGNC:HGNC:19798 +326312 RPS12P1 HGNC:HGNC:19787 +326315 PTTG4P HGNC:HGNC:20055 +326316 RPS15AP2 HGNC:HGNC:19671 +326317 RPS15AP3 HGNC:HGNC:19674 +326320 RPS18P2 HGNC:HGNC:19801 +326321 RPS24P2 HGNC:HGNC:19791 +326322 RPS24P3 HGNC:HGNC:19797 +326323 RPS27AP4 HGNC:HGNC:19775 +326325 RPS2P2 HGNC:HGNC:19790 +326326 RPS2P3 HGNC:HGNC:19806 +326337 SSXP4 HGNC:HGNC:30641 +326339 SSXP5 HGNC:HGNC:30642 +326340 ZAR1 MIM:607520|HGNC:HGNC:20436|Ensembl:ENSG00000182223|Vega:OTTHUMG00000102093 +326341 SSXP3 HGNC:HGNC:30640 +326342 ADGRE4P MIM:612305|HGNC:HGNC:19240|Ensembl:ENSG00000268758 +326343 MT1DP HGNC:HGNC:7396 +326585 SSXP8 HGNC:HGNC:30199 +326586 SSXP9 HGNC:HGNC:30645 +326587 SSXP6 HGNC:HGNC:30643 +326590 SSXP7 HGNC:HGNC:30644 +326591 MORF4L1P1 HGNC:HGNC:20400 +326593 MORF4L1P3 HGNC:HGNC:20402 +326594 MORF4L1P2 HGNC:HGNC:20401 +326596 MAD2L1P1 HGNC:HGNC:20019 +326603 MTCO1P2 HGNC:HGNC:19932 +326605 NCOA4P1 HGNC:HGNC:20022 +326606 NDUFB8P1 HGNC:HGNC:20023 +326607 NMNAT1P1 HGNC:HGNC:20024 +326608 NPM1P20 HGNC:HGNC:20140 +326609 NT5CP1 HGNC:HGNC:20046 +326611 NT5CP2 HGNC:HGNC:20047 +326613 NUTF2P2 HGNC:HGNC:19934 +326614 PEBP1P1 HGNC:HGNC:20054 +326615 MED15P1 HGNC:HGNC:19271 +326616 PDLIM1P1 HGNC:HGNC:20026 +326617 PSMA3P HGNC:HGNC:20029 +326624 RAB37 MIM:609956|HGNC:HGNC:30268|Ensembl:ENSG00000172794|Vega:OTTHUMG00000134282 +326625 MMAB MIM:607568|HGNC:HGNC:19331|Ensembl:ENSG00000139428|Vega:OTTHUMG00000169255 +326626 PTMAP7 HGNC:HGNC:20031 +326627 RANBP20P HGNC:HGNC:19734 +326628 RPA2P1 HGNC:HGNC:19676 +327657 SERPINA9 MIM:615677|HGNC:HGNC:15995|Ensembl:ENSG00000170054|Vega:OTTHUMG00000167710 +327658 PUDPP1 HGNC:HGNC:20200 +327659 PUDPP2 HGNC:HGNC:20195 +333926 PPM1J MIM:609957|HGNC:HGNC:20785|Ensembl:ENSG00000155367|Vega:OTTHUMG00000012019 +333929 SNAI3 MIM:612741|HGNC:HGNC:18411|Ensembl:ENSG00000185669|Vega:OTTHUMG00000173243 +333932 HIST2H3A HGNC:HGNC:20505|Ensembl:ENSG00000203852|Vega:OTTHUMG00000012094 +337867 UBAC2 HGNC:HGNC:20486|Ensembl:ENSG00000134882|Vega:OTTHUMG00000017267 +337872 HIST3H2BA HGNC:HGNC:20515 +337873 HIST2H2BC HGNC:HGNC:20516|Ensembl:ENSG00000203819 +337874 HIST2H2BD HGNC:HGNC:20517 +337875 HIST2H2BA HGNC:HGNC:20560 +337876 CHSY3 MIM:609963|HGNC:HGNC:24293|Ensembl:ENSG00000198108|Vega:OTTHUMG00000163043 +337878 KRTAP7-1 HGNC:HGNC:18934|Ensembl:ENSG00000274749|Vega:OTTHUMG00000188305 +337879 KRTAP8-1 HGNC:HGNC:18935|Ensembl:ENSG00000183640|Vega:OTTHUMG00000057771 +337880 KRTAP11-1 MIM:600064|HGNC:HGNC:18922|Ensembl:ENSG00000182591|Vega:OTTHUMG00000057773 +337882 KRTAP19-1 HGNC:HGNC:18936|Ensembl:ENSG00000184351|Vega:OTTHUMG00000057768 +337892 MGR3 MIM:607498 +337893 BULN MIM:607499 +337895 BMIQ3 MIM:607446|HGNC:HGNC:23829 +337959 KRTAP13-2 HGNC:HGNC:18923|Ensembl:ENSG00000182816|Vega:OTTHUMG00000057793 +337960 KRTAP13-3 HGNC:HGNC:18925|Ensembl:ENSG00000240432|Vega:OTTHUMG00000057776 +337963 KRTAP23-1 HGNC:HGNC:18928|Ensembl:ENSG00000186980|Vega:OTTHUMG00000057792 +337964 KRTAP13-5P HGNC:HGNC:18929 +337965 KRTAP13-6P HGNC:HGNC:18930 +337966 KRTAP6-1 HGNC:HGNC:18931|Ensembl:ENSG00000184724|Vega:OTTHUMG00000057788 +337967 KRTAP6-2 HGNC:HGNC:18932|Ensembl:ENSG00000186930|Vega:OTTHUMG00000057794 +337968 KRTAP6-3 HGNC:HGNC:18933|Ensembl:ENSG00000212938|Vega:OTTHUMG00000057791 +337969 KRTAP19-2 HGNC:HGNC:18937|Ensembl:ENSG00000186965|Vega:OTTHUMG00000057772 +337970 KRTAP19-3 HGNC:HGNC:18938|Ensembl:ENSG00000244025|Vega:OTTHUMG00000057782 +337971 KRTAP19-4 HGNC:HGNC:18939|Ensembl:ENSG00000186967|Vega:OTTHUMG00000057767 +337972 KRTAP19-5 HGNC:HGNC:18940|Ensembl:ENSG00000186977|Vega:OTTHUMG00000057774 +337973 KRTAP19-6 HGNC:HGNC:18941|Ensembl:ENSG00000186925|Vega:OTTHUMG00000057779 +337974 KRTAP19-7 HGNC:HGNC:18942|Ensembl:ENSG00000244362|Vega:OTTHUMG00000057785 +337975 KRTAP20-1 HGNC:HGNC:18943|Ensembl:ENSG00000244624|Vega:OTTHUMG00000057801 +337976 KRTAP20-2 HGNC:HGNC:18944|Ensembl:ENSG00000184032|Vega:OTTHUMG00000057786 +337977 KRTAP21-1 HGNC:HGNC:18945|Ensembl:ENSG00000187005|Vega:OTTHUMG00000057777 +337978 KRTAP21-2 HGNC:HGNC:18946|Ensembl:ENSG00000187026|Vega:OTTHUMG00000057769 +337979 KRTAP22-1 HGNC:HGNC:18947|Ensembl:ENSG00000186924|Vega:OTTHUMG00000057778 +337980 KRTAP8-2P HGNC:HGNC:18948 +337981 KRTAP8-3P HGNC:HGNC:18949 +337982 KRTAP19-9P HGNC:HGNC:18950 +337983 KRTAP19-10P HGNC:HGNC:18951 +337984 KRTAP19-11P HGNC:HGNC:18952 +337985 KRTAP20-3 HGNC:HGNC:34001|Ensembl:ENSG00000206104|Vega:OTTHUMG00000057798 +337986 KRTAP21-4P HGNC:HGNC:18954 +337991 DFNB38 MIM:608219|HGNC:HGNC:19210 +338002 LINC00524 HGNC:HGNC:20118|Ensembl:ENSG00000259023 +338004 LINC00226 HGNC:HGNC:20168 +338005 LINC00221 HGNC:HGNC:20169|Ensembl:ENSG00000270816 +338017 KRT8P1 HGNC:HGNC:20281 +338027 BMND2 MIM:605833 +338030 GLM4 MIM:607248 +338069 ST7-OT4 HGNC:HGNC:18835|Ensembl:ENSG00000214188 +338090 SPG24 MIM:607584|HGNC:HGNC:22993 +338091 PSMD10P3 HGNC:HGNC:30152 +338094 FAM151A HGNC:HGNC:25032|Ensembl:ENSG00000162391|Vega:OTTHUMG00000009888 +338095 PSME2P3 HGNC:HGNC:30156 +338096 PSME2P4 HGNC:HGNC:30157 +338097 PSME2P5 HGNC:HGNC:30158 +338098 PSME2P6 HGNC:HGNC:30159 +338099 PSME2P2 HGNC:HGNC:30160 +338321 NLRP9 MIM:609663|HGNC:HGNC:22941|Ensembl:ENSG00000185792|Vega:OTTHUMG00000180920 +338322 NLRP10 MIM:609662|HGNC:HGNC:21464|Ensembl:ENSG00000182261|Vega:OTTHUMG00000165673 +338323 NLRP14 MIM:609665|HGNC:HGNC:22939|Ensembl:ENSG00000158077|Vega:OTTHUMG00000165508 +338324 S100A7A MIM:617427|HGNC:HGNC:21657|Ensembl:ENSG00000184330|Vega:OTTHUMG00000013122 +338328 GPIHBP1 MIM:612757|HGNC:HGNC:24945|Ensembl:ENSG00000277494|Vega:OTTHUMG00000164950 +338331 AZON MIM:606766 +338332 CELIAC5 MIM:607202 +338333 PAPA3 MIM:607324 +338334 CHDS1 MIM:607339 +338339 CLEC4D MIM:609964|HGNC:HGNC:14554|Ensembl:ENSG00000166527|Vega:OTTHUMG00000168674 +338340 MMS MIM:156240 +338342 MGR4 MIM:607501 +338376 IFNE MIM:615223|HGNC:HGNC:18163|Ensembl:ENSG00000184995|Vega:OTTHUMG00000019672 +338382 RAB7B HGNC:HGNC:30513|Ensembl:ENSG00000276600|Vega:OTTHUMG00000189246 +338386 HSR MIM:139900 +338388 MRPS16P3 HGNC:HGNC:29733 +338389 MRPS24P1 HGNC:HGNC:29759 +338390 MRPS25P1 HGNC:HGNC:29760 +338391 HIST2H2BB HGNC:HGNC:20654 +338396 TAS2R2P HGNC:HGNC:20615 +338398 TAS2R60 MIM:613968|HGNC:HGNC:20639|Ensembl:ENSG00000185899|Vega:OTTHUMG00000154891 +338399 TAS2R62P HGNC:HGNC:20640 +338411 TELAB1 MIM:187260|HGNC:HGNC:20680 +338412 TAS2R64P HGNC:HGNC:20642 +338413 TAS2R63P HGNC:HGNC:20641 +338414 TAS2R18P HGNC:HGNC:19107 +338427 SNORD108 HGNC:HGNC:32772|Ensembl:ENSG00000239014 +338428 SNORD109A HGNC:HGNC:32773|Ensembl:ENSG00000274640 +338429 SNORD109B HGNC:HGNC:32774|Ensembl:ENSG00000239169 +338433 SNORD115-1 MIM:609837|HGNC:HGNC:33020|Ensembl:ENSG00000201831 +338434 CANDN1 MIM:607644|HGNC:HGNC:20683 +338435 SCA25 MIM:608703|HGNC:HGNC:20684 +338436 BLACE MIM:608450|HGNC:HGNC:20484|Ensembl:ENSG00000204960|Vega:OTTHUMG00000151351 +338440 ANO9 HGNC:HGNC:20679|Ensembl:ENSG00000185101|Vega:OTTHUMG00000165446 +338442 HCAR2 MIM:609163|HGNC:HGNC:24827|Ensembl:ENSG00000182782|Vega:OTTHUMG00000162722 +338448 GTF2IP2 HGNC:HGNC:16082 +338470 MESTP1 HGNC:HGNC:29660 +338557 FFAR4 MIM:609044|HGNC:HGNC:19061|Ensembl:ENSG00000186188|Vega:OTTHUMG00000034409 +338567 KCNK18 MIM:613655|HGNC:HGNC:19439|Ensembl:ENSG00000186795|Vega:OTTHUMG00000019120 +338579 ANKRD30BP3 HGNC:HGNC:27873 +338588 LINC00705 HGNC:HGNC:27874 +338591 CHCHD3P1 HGNC:HGNC:44697 +338596 ST8SIA6 MIM:610139|HGNC:HGNC:23317|Ensembl:ENSG00000148488|Vega:OTTHUMG00000017748 +338599 DUPD1 HGNC:HGNC:23481|Ensembl:ENSG00000188716|Vega:OTTHUMG00000018512 +338611 RPS26P40 HGNC:HGNC:36906 +338637 OR52M2P HGNC:HGNC:15226 +338645 LUZP2 MIM:608178|HGNC:HGNC:23206|Ensembl:ENSG00000187398|Vega:OTTHUMG00000166109 +338651 KRTAP5-AS1 HGNC:HGNC:27877|Ensembl:ENSG00000233930 +338653 KCNQ1-AS1 HGNC:HGNC:42790|Ensembl:ENSG00000229414 +338657 CCDC84 HGNC:HGNC:30460|Ensembl:ENSG00000186166|Vega:OTTHUMG00000166348 +338661 TMEM225 HGNC:HGNC:32390|Ensembl:ENSG00000204300|Vega:OTTHUMG00000165959 +338662 OR8D4 HGNC:HGNC:14840|Ensembl:ENSG00000181518|Vega:OTTHUMG00000165960 +338667 VSIG10L2 HGNC:HGNC:27879 +338674 OR5F1 MIM:608492|HGNC:HGNC:8343|Ensembl:ENSG00000149133|Vega:OTTHUMG00000166825 +338675 OR5AP2 HGNC:HGNC:15258|Ensembl:ENSG00000172464|Vega:OTTHUMG00000166865 +338692 ANKRD13D MIM:615126|HGNC:HGNC:27880|Ensembl:ENSG00000172932|Vega:OTTHUMG00000162929 +338694 LOC338694 Ensembl:ENSG00000261070 +338699 ANKRD42 HGNC:HGNC:26752|Ensembl:ENSG00000137494|Vega:OTTHUMG00000167075 +338707 B4GALNT4 HGNC:HGNC:26315|Ensembl:ENSG00000182272|Vega:OTTHUMG00000119075 +338739 CSTF3-AS1 HGNC:HGNC:27882|Ensembl:ENSG00000247151 +338751 OR52L1 HGNC:HGNC:14785|Ensembl:ENSG00000183313|Vega:OTTHUMG00000165374 +338755 OR2AG2 HGNC:HGNC:15143|Ensembl:ENSG00000188124|Vega:OTTHUMG00000165868 +338758 ATP2B1-AS1 HGNC:HGNC:27883|Ensembl:ENSG00000271614 +338761 C1QL4 MIM:615229|HGNC:HGNC:31416|Ensembl:ENSG00000186897|Vega:OTTHUMG00000169515 +338773 TMEM119 HGNC:HGNC:27884|Ensembl:ENSG00000183160|Vega:OTTHUMG00000169410 +338785 KRT79 MIM:611160|HGNC:HGNC:28930|Ensembl:ENSG00000185640|Vega:OTTHUMG00000169878 +338797 LINC02370 HGNC:HGNC:27885 +338799 LINC01089 HGNC:HGNC:27886|Ensembl:ENSG00000212694 +338805 ST13P8 HGNC:HGNC:38743 +338809 C12orf74 HGNC:HGNC:27887|Ensembl:ENSG00000214215|Vega:OTTHUMG00000170105 +338811 FAM19A2 MIM:617496|HGNC:HGNC:21589|Ensembl:ENSG00000198673|Vega:OTTHUMG00000170207 +338817 LINC01252 HGNC:HGNC:27888|Ensembl:ENSG00000247157 +338821 SLCO1B7 HGNC:HGNC:32934|Ensembl:ENSG00000205754|Vega:OTTHUMG00000169045 +338862 LINC00550 HGNC:HGNC:43688|Ensembl:ENSG00000281778 +338864 LINC00347 HGNC:HGNC:27890|Ensembl:ENSG00000236678 +338870 RPS12P23 HGNC:HGNC:35573 +338872 C1QTNF9 MIM:614285|HGNC:HGNC:28732|Ensembl:ENSG00000240654|Vega:OTTHUMG00000016576 +338879 RNASE10 HGNC:HGNC:19275|Ensembl:ENSG00000182545|Vega:OTTHUMG00000170986 +338917 VSX2 MIM:142993|HGNC:HGNC:1975|Ensembl:ENSG00000119614|Vega:OTTHUMG00000171206 +338949 TMEM202 HGNC:HGNC:33733|Ensembl:ENSG00000187806|Vega:OTTHUMG00000172716 +338963 LOC338963 Ensembl:ENSG00000228141 +339005 WHAMMP3 HGNC:HGNC:27892 +339039 PKD1P3 HGNC:HGNC:30067 +339044 PKD1P1 HGNC:HGNC:30065 +339059 LOC339059 Ensembl:ENSG00000182376 +339105 PRSS53 MIM:610561|HGNC:HGNC:34407|Ensembl:ENSG00000151006|Vega:OTTHUMG00000047358 +339122 RAB43 HGNC:HGNC:19983|Ensembl:ENSG00000172780|Vega:OTTHUMG00000137364 +339123 JMJD8 HGNC:HGNC:14148|Ensembl:ENSG00000161999|Vega:OTTHUMG00000172950 +339145 FAM92B MIM:617274|HGNC:HGNC:24781|Ensembl:ENSG00000153789|Vega:OTTHUMG00000187060 +339166 LOC339166 Ensembl:ENSG00000179314 +339168 TMEM95 HGNC:HGNC:27898|Ensembl:ENSG00000182896|Vega:OTTHUMG00000132899 +339175 METTL2A HGNC:HGNC:25755|Ensembl:ENSG00000087995|Vega:OTTHUMG00000164527 +339184 CCDC144NL HGNC:HGNC:33735|Ensembl:ENSG00000205212|Vega:OTTHUMG00000132271 +339186 KRT17P4 HGNC:HGNC:50722 +339192 LOC339192 - +339201 ASB16-AS1 HGNC:HGNC:25442|Ensembl:ENSG00000267080 +339210 C17orf67 HGNC:HGNC:27900|Ensembl:ENSG00000214226|Vega:OTTHUMG00000132083 +339221 ENPP7 MIM:616997|HGNC:HGNC:23764|Ensembl:ENSG00000182156|Vega:OTTHUMG00000177462 +339229 OXLD1 HGNC:HGNC:27901|Ensembl:ENSG00000204237|Vega:OTTHUMG00000178063 +339230 CCDC137 MIM:614271|HGNC:HGNC:33451|Ensembl:ENSG00000185298|Vega:OTTHUMG00000178064 +339231 ARL16 HGNC:HGNC:27902|Ensembl:ENSG00000214087|Vega:OTTHUMG00000178103 +339240 KRT17P5 HGNC:HGNC:50723 +339241 KRT17P2 HGNC:HGNC:6429 +339244 KRT16P4 HGNC:HGNC:37809 +339256 NOS2P3 HGNC:HGNC:35124 +339257 TNPO1P3 HGNC:HGNC:50718 +339258 KRT17P7 HGNC:HGNC:50725 +339260 LOC339260 Ensembl:ENSG00000233098 +339263 C17orf51 HGNC:HGNC:27904|Ensembl:ENSG00000212719|Vega:OTTHUMG00000186498 +339287 MSL1 MIM:614801|HGNC:HGNC:27905|Ensembl:ENSG00000188895|Vega:OTTHUMG00000179629 +339290 LINC00667 HGNC:HGNC:27906|Ensembl:ENSG00000263753 +339291 LRRC30 HGNC:HGNC:30219|Ensembl:ENSG00000206422|Vega:OTTHUMG00000178479 +339298 LOC339298 Ensembl:ENSG00000263547 +339302 CPLX4 MIM:609586|HGNC:HGNC:24330|Ensembl:ENSG00000166569|Vega:OTTHUMG00000132756 +339318 ZNF181 MIM:606741|HGNC:HGNC:12971|Ensembl:ENSG00000197841|Vega:OTTHUMG00000157508 +339324 ZNF260 MIM:613749|HGNC:HGNC:13499|Ensembl:ENSG00000254004|Vega:OTTHUMG00000048155 +339327 ZNF546 HGNC:HGNC:28671|Ensembl:ENSG00000187187|Vega:OTTHUMG00000182578 +339344 MYPOP HGNC:HGNC:20178|Ensembl:ENSG00000176182|Vega:OTTHUMG00000182486 +339345 NANOS2 MIM:608228|HGNC:HGNC:23292|Ensembl:ENSG00000188425|Vega:OTTHUMG00000182487 +339352 LOC339352 - +339366 ADAMTSL5 HGNC:HGNC:27912|Ensembl:ENSG00000185761|Vega:OTTHUMG00000180093 +339390 CLEC4G MIM:616256|HGNC:HGNC:24591|Ensembl:ENSG00000182566|Vega:OTTHUMG00000182519 +339396 NEFHP1 HGNC:HGNC:7738 +339398 LINGO4 MIM:609794|HGNC:HGNC:31814|Ensembl:ENSG00000213171|Vega:OTTHUMG00000013059 +339400 FLG-AS1 HGNC:HGNC:27913|Ensembl:ENSG00000237975 +339403 RXFP4 MIM:609043|HGNC:HGNC:14666|Ensembl:ENSG00000173080|Vega:OTTHUMG00000017463 +339416 ANKRD45 HGNC:HGNC:24786|Ensembl:ENSG00000183831|Vega:OTTHUMG00000040546 +339442 LINC01343 HGNC:HGNC:50553|Ensembl:ENSG00000237290 +339448 C1orf174 HGNC:HGNC:27915|Ensembl:ENSG00000198912|Vega:OTTHUMG00000003739 +339451 KLHL17 HGNC:HGNC:24023|Ensembl:ENSG00000187961|Vega:OTTHUMG00000040721 +339453 TMEM240 MIM:616101|HGNC:HGNC:25186|Ensembl:ENSG00000205090|Vega:OTTHUMG00000042193 +339456 TMEM52 HGNC:HGNC:27916|Ensembl:ENSG00000178821|Vega:OTTHUMG00000000944 +339468 LOC339468 - +339476 ERVMER61-1 HGNC:HGNC:27919 +339479 BRINP3 HGNC:HGNC:22393|Ensembl:ENSG00000162670|Vega:OTTHUMG00000035533 +339483 MTMR9LP HGNC:HGNC:27920 +339487 ZBTB8OS MIM:615891|HGNC:HGNC:24094|Ensembl:ENSG00000176261|Vega:OTTHUMG00000007856 +339488 TFAP2E MIM:614428|HGNC:HGNC:30774|Ensembl:ENSG00000116819|Vega:OTTHUMG00000004388 +339500 ZNF678 HGNC:HGNC:28652|Ensembl:ENSG00000181450|Vega:OTTHUMG00000037700 +339501 PRSS38 HGNC:HGNC:29625|Ensembl:ENSG00000185888|Vega:OTTHUMG00000037701 +339505 LINC01141 HGNC:HGNC:49455 +339512 CCDC190 HGNC:HGNC:28736|Ensembl:ENSG00000185860|Vega:OTTHUMG00000034421 +339521 FAM58BP HGNC:HGNC:27373 +339524 LINC01140 HGNC:HGNC:27922|Ensembl:ENSG00000267272 +339529 LOC339529 Ensembl:ENSG00000226828 +339535 LINC01139 HGNC:HGNC:27924|Ensembl:ENSG00000215808 +339539 LOC339539 - +339541 C1orf228 HGNC:HGNC:34345|Ensembl:ENSG00000198520|Vega:OTTHUMG00000007834 +339559 ZFP69 HGNC:HGNC:24708|Ensembl:ENSG00000187815|Vega:OTTHUMG00000007303 +339562 IGKV1OR2-118 HGNC:HGNC:37488|IMGT/GENE-DB:IGKV1/OR2-118 +339568 LINC01734 HGNC:HGNC:52522|Ensembl:ENSG00000230324 +339593 LOC339593 - +339622 LINC01692 HGNC:HGNC:52480|Ensembl:ENSG00000226983 +339665 SLC35E4 HGNC:HGNC:17058|Ensembl:ENSG00000100036|Vega:OTTHUMG00000151110 +339666 LOC339666 Ensembl:ENSG00000230736 +339669 TEX33 HGNC:HGNC:28568|Ensembl:ENSG00000185264|Vega:OTTHUMG00000150531 +339674 LINC00634 HGNC:HGNC:27930|Ensembl:ENSG00000205704 +339685 LOC339685 - +339736 AK2P2 HGNC:HGNC:33542 +339742 FAM201B HGNC:HGNC:27933 +339745 SPOPL HGNC:HGNC:27934|Ensembl:ENSG00000144228|Vega:OTTHUMG00000153635 +339751 MAP3K20-AS1 HGNC:HGNC:27935|Ensembl:ENSG00000238133 +339761 CYP27C1 HGNC:HGNC:33480|Ensembl:ENSG00000186684|Vega:OTTHUMG00000153400 +339766 MROH2A HGNC:HGNC:27936|Ensembl:ENSG00000185038|Vega:OTTHUMG00000059037 +339768 ESPNL HGNC:HGNC:27937|Ensembl:ENSG00000144488|Vega:OTTHUMG00000133335 +339778 C2orf70 HGNC:HGNC:27938|Ensembl:ENSG00000173557|Vega:OTTHUMG00000151994 +339779 PRR30 HGNC:HGNC:28677|Ensembl:ENSG00000186143|Vega:OTTHUMG00000128408 +339781 KRT18P19 HGNC:HGNC:33387 +339788 LINC00298 HGNC:HGNC:49257|Ensembl:ENSG00000235665 +339789 LINC00299 HGNC:HGNC:27940|Ensembl:ENSG00000236790 +339799 EIF3FP3 HGNC:HGNC:37625 +339803 LOC339803 Ensembl:ENSG00000212978 +339804 C2orf74 HGNC:HGNC:34439|Ensembl:ENSG00000237651|Vega:OTTHUMG00000187090 +339807 LOC339807 Ensembl:ENSG00000233694 +339822 LINC01115 HGNC:HGNC:49258|Ensembl:ENSG00000237667 +339829 CCDC39 MIM:613798|HGNC:HGNC:25244|Ensembl:ENSG00000145075|Vega:OTTHUMG00000157857 +339834 CCDC36 HGNC:HGNC:27945|Ensembl:ENSG00000173421|Vega:OTTHUMG00000155920 +339843 WWP1P1 HGNC:HGNC:48944 +339845 ASS1P7 HGNC:HGNC:770 +339855 KY MIM:605739|HGNC:HGNC:26576|Ensembl:ENSG00000174611|Vega:OTTHUMG00000159788 +339862 LOC339862 - +339874 LOC339874 Ensembl:ENSG00000250608 +339879 ALG1L6P HGNC:HGNC:44375 +339881 EIF4BP8 HGNC:HGNC:37941 +339883 C3orf35 MIM:611429|HGNC:HGNC:24082|Ensembl:ENSG00000198590 +339894 LINC00880 HGNC:HGNC:27948|Ensembl:ENSG00000243629 +339896 GADL1 MIM:615601|HGNC:HGNC:27949|Ensembl:ENSG00000144644|Vega:OTTHUMG00000130621 +339897 CNN2P6 HGNC:HGNC:39531 +339902 LOC339902 - +339906 PRSS42 HGNC:HGNC:30716|Ensembl:ENSG00000178055|Vega:OTTHUMG00000156496 +339910 MRPS35P1 HGNC:HGNC:29768 +339926 EHHADH-AS1 HGNC:HGNC:44133|Ensembl:ENSG00000223358 +339929 LPP-AS2 HGNC:HGNC:27952|Ensembl:ENSG00000270959 +339942 H1FX-AS1 HGNC:HGNC:27953 +339965 CCDC158 HGNC:HGNC:26374|Ensembl:ENSG00000163749|Vega:OTTHUMG00000160916 +339966 LOC339966 - +339967 TMPRSS11A MIM:611704|HGNC:HGNC:27954|Ensembl:ENSG00000187054|Vega:OTTHUMG00000129303 +339970 GCOM2 MIM:608311|HGNC:HGNC:15712 +339975 LOC339975 - +339976 TRIML1 HGNC:HGNC:26698|Ensembl:ENSG00000184108|Vega:OTTHUMG00000160237 +339977 LRRC66 HGNC:HGNC:34299|Ensembl:ENSG00000188993|Vega:OTTHUMG00000160623 +339978 LINC02260 HGNC:HGNC:27956|Ensembl:ENSG00000250456 +339983 NAT8L MIM:610647|HGNC:HGNC:26742|Ensembl:ENSG00000185818 +339988 LINC002481 HGNC:HGNC:27958 +340017 LINC02433 HGNC:HGNC:27959|Ensembl:ENSG00000234111 +340024 SLC6A19 MIM:608893|HGNC:HGNC:27960|Ensembl:ENSG00000174358|Vega:OTTHUMG00000161636 +340037 PRR7-AS1 HGNC:HGNC:27961 +340061 TMEM173 MIM:612374|HGNC:HGNC:27962|Ensembl:ENSG00000184584|Vega:OTTHUMG00000129239 +340069 FAM170A HGNC:HGNC:27963|Ensembl:ENSG00000164334|Vega:OTTHUMG00000162946 +340073 C5orf66-AS2 HGNC:HGNC:27964|Ensembl:ENSG00000249647 +340074 LINC01959 HGNC:HGNC:27965|Ensembl:ENSG00000251045 +340075 ARSI MIM:610009|HGNC:HGNC:32521|Ensembl:ENSG00000183876|Vega:OTTHUMG00000163479 +340089 LOC340089 - +340090 LOC340090 - +340094 LINC01020 HGNC:HGNC:27968|Ensembl:ENSG00000215231 +340096 H3.X - +340107 LINC02239 HGNC:HGNC:27969|Ensembl:ENSG00000248908 +340113 LINC02120 HGNC:HGNC:27971|Ensembl:ENSG00000248279 +340120 ANKRD34B HGNC:HGNC:33736|Ensembl:ENSG00000189127|Vega:OTTHUMG00000162541 +340146 SLC35D3 MIM:612519|HGNC:HGNC:15621|Ensembl:ENSG00000182747|Vega:OTTHUMG00000015651 +340152 ZC3H12D MIM:611106|HGNC:HGNC:21175|Ensembl:ENSG00000178199|Vega:OTTHUMG00000015786 +340156 MYLK4 HGNC:HGNC:27972|Ensembl:ENSG00000145949|Vega:OTTHUMG00000014121 +340168 DPPA5 MIM:611111|HGNC:HGNC:19201|Ensembl:ENSG00000203909|Vega:OTTHUMG00000015025 +340184 LOC340184 - +340192 IQCB2P HGNC:HGNC:17727 +340198 IFITM4P HGNC:HGNC:21669|Ensembl:ENSG00000235821 +340204 CLPSL1 HGNC:HGNC:21251|Ensembl:ENSG00000204140|Vega:OTTHUMG00000014582 +340205 TREML1 MIM:609714|HGNC:HGNC:20434|Ensembl:ENSG00000161911|Vega:OTTHUMG00000016231 +340206 TREML3P MIM:609716|HGNC:HGNC:30806|Ensembl:ENSG00000184106 +340217 NANOGP3 HGNC:HGNC:23101 +340221 TNRC18P3 HGNC:HGNC:34015 +340252 ZNF680 HGNC:HGNC:26897|Ensembl:ENSG00000173041|Vega:OTTHUMG00000156542 +340260 UNCX HGNC:HGNC:33194|Ensembl:ENSG00000164853|Vega:OTTHUMG00000152022 +340267 COL28A1 MIM:609996|HGNC:HGNC:22442|Ensembl:ENSG00000215018|Vega:OTTHUMG00000150034 +340268 LOC340268 - +340273 ABCB5 MIM:611785|HGNC:HGNC:46|Ensembl:ENSG00000004846|Vega:OTTHUMG00000094789 +340274 ASS1P11 HGNC:HGNC:761 +340277 FAM221A HGNC:HGNC:27977|Ensembl:ENSG00000188732|Vega:OTTHUMG00000128463 +340286 FAM183BP HGNC:HGNC:34511|Ensembl:ENSG00000164556 +340307 CTAGE6 HGNC:HGNC:28644|Ensembl:ENSG00000271321|Vega:OTTHUMG00000157770 +340348 TSPAN33 MIM:610120|HGNC:HGNC:28743|Ensembl:ENSG00000158457|Vega:OTTHUMG00000158420 +340351 AGBL3 MIM:617346|HGNC:HGNC:27981|Ensembl:ENSG00000146856|Vega:OTTHUMG00000155406 +340357 LOC340357 Ensembl:ENSG00000254813 +340359 KLHL38 HGNC:HGNC:34435|Ensembl:ENSG00000175946|Vega:OTTHUMG00000164983 +340371 NRBP2 MIM:615563|HGNC:HGNC:19339|Ensembl:ENSG00000185189|Vega:OTTHUMG00000165157 +340385 ZNF517 HGNC:HGNC:27984|Ensembl:ENSG00000197363|Vega:OTTHUMG00000165199 +340390 WDR97 HGNC:HGNC:26959|Ensembl:ENSG00000179698|Vega:OTTHUMG00000165245 +340393 TMEM249 HGNC:HGNC:44155|Ensembl:ENSG00000261587|Vega:OTTHUMG00000165167 +340419 RSPO2 MIM:610575|HGNC:HGNC:28583|Ensembl:ENSG00000147655|Vega:OTTHUMG00000164893 +340441 POTEA MIM:608915|HGNC:HGNC:33893 +340443 RPS5P5 HGNC:HGNC:35626 +340451 CPP HGNC:HGNC:2322 +340460 KRT18P24 HGNC:HGNC:33393 +340481 ZDHHC21 MIM:614605|HGNC:HGNC:20750|Ensembl:ENSG00000175893|Vega:OTTHUMG00000019573 +340485 ACER2 MIM:613492|HGNC:HGNC:23675|Ensembl:ENSG00000177076|Vega:OTTHUMG00000019644 +340499 IMPDH1P1 HGNC:HGNC:19912 +340501 TCEA1P3 HGNC:HGNC:30569 +340508 GAS2L1P2 HGNC:HGNC:27986|Ensembl:ENSG00000228376 +340512 LOC340512 Ensembl:ENSG00000230782 +340515 LINC01501 HGNC:HGNC:27988 +340526 RTL5 HGNC:HGNC:29430|Ensembl:ENSG00000242732|Vega:OTTHUMG00000021808 +340527 NHSL2 HGNC:HGNC:33737|Ensembl:ENSG00000204131|Vega:OTTHUMG00000021807 +340529 PABPC1L2A HGNC:HGNC:27989|Ensembl:ENSG00000186288|Vega:OTTHUMG00000021824 +340533 NEXMIF MIM:300524|HGNC:HGNC:29433|Ensembl:ENSG00000050030|Vega:OTTHUMG00000021860 +340542 BEX5 MIM:300693|HGNC:HGNC:27990|Ensembl:ENSG00000184515|Vega:OTTHUMG00000022049 +340543 TCEAL5 HGNC:HGNC:22282|Ensembl:ENSG00000204065|Vega:OTTHUMG00000022092 +340544 MORF4L2-AS1 HGNC:HGNC:27991 +340547 VSIG1 MIM:300620|HGNC:HGNC:28675|Ensembl:ENSG00000101842|Vega:OTTHUMG00000022175 +340554 ZC3H12B MIM:300889|HGNC:HGNC:17407|Ensembl:ENSG00000102053|Vega:OTTHUMG00000021719 +340562 SATL1 HGNC:HGNC:27992|Ensembl:ENSG00000184788|Vega:OTTHUMG00000021931 +340569 LOC340569 - +340571 SIAH1P1 HGNC:HGNC:30966 +340578 DCAF12L2 HGNC:HGNC:32950|Ensembl:ENSG00000198354|Vega:OTTHUMG00000022348 +340581 LINC02243 HGNC:HGNC:53129|Ensembl:ENSG00000236091 +340591 CA5BP1 HGNC:HGNC:29544|Ensembl:ENSG00000186312 +340595 RTL4 HGNC:HGNC:25214|Ensembl:ENSG00000187823|Vega:OTTHUMG00000159706 +340596 LHFPL1 MIM:300566|HGNC:HGNC:6587|Ensembl:ENSG00000182508|Vega:OTTHUMG00000022214 +340598 KRT18P48 HGNC:HGNC:33418 +340600 ATF4P2 HGNC:HGNC:34025 +340602 CXorf67 HGNC:HGNC:33738|Ensembl:ENSG00000187690|Vega:OTTHUMG00000187481 +340618 FAM41AY1 HGNC:HGNC:23955 +340654 LIPM MIM:613923|HGNC:HGNC:23455|Ensembl:ENSG00000173239|Vega:OTTHUMG00000018698 +340665 CYP26C1 MIM:608428|HGNC:HGNC:20577|Ensembl:ENSG00000187553|Vega:OTTHUMG00000018766 +340706 VWA2 HGNC:HGNC:24709|Ensembl:ENSG00000165816|Vega:OTTHUMG00000019082 +340719 NANOS1 MIM:608226|HGNC:HGNC:23044|Ensembl:ENSG00000188613|Vega:OTTHUMG00000019141 +340745 LRIT2 HGNC:HGNC:23443|Ensembl:ENSG00000204033|Vega:OTTHUMG00000018633 +340749 RPL7AP8 HGNC:HGNC:23738 +340780 IMPDH1P5 HGNC:HGNC:33960 +340784 HMX3 MIM:613380|HGNC:HGNC:5019|Ensembl:ENSG00000188620|Vega:OTTHUMG00000019199 +340811 AKR1C8P HGNC:HGNC:23469|Ensembl:ENSG00000264006 +340844 AHCYP1 HGNC:HGNC:44993 +340888 AKR1B10P1 HGNC:HGNC:45062 +340895 MALRD1 HGNC:HGNC:24331|Ensembl:ENSG00000204740|Vega:OTTHUMG00000017779 +340900 EBLN1 MIM:613249|HGNC:HGNC:39430|Ensembl:ENSG00000223601|Vega:OTTHUMG00000017801 +340947 EIF3LP3 HGNC:HGNC:44976 +340970 TRIM53CP HGNC:HGNC:43979 +340980 OR52B6 HGNC:HGNC:15211|Ensembl:ENSG00000187747|Vega:OTTHUMG00000066906 +340990 OTOG MIM:604487|HGNC:HGNC:8516|Ensembl:ENSG00000188162|Vega:OTTHUMG00000149905 +341019 DCDC1 MIM:608062|HGNC:HGNC:20625|Ensembl:ENSG00000170959|Vega:OTTHUMG00000150144 +341032 C11orf53 HGNC:HGNC:30527|Ensembl:ENSG00000150750|Vega:OTTHUMG00000166656 +341056 LOC341056 - +341112 WARSP1 HGNC:HGNC:50482 +341116 MS4A10 MIM:608403|HGNC:HGNC:13368|Ensembl:ENSG00000172689|Vega:OTTHUMG00000167689 +341128 OR7E1P HGNC:HGNC:8391 +341148 CYCSP27 HGNC:HGNC:24401 +341152 OR2AT4 HGNC:HGNC:19620|Ensembl:ENSG00000171561|Vega:OTTHUMG00000165370 +341208 HEPHL1 HGNC:HGNC:30477|Ensembl:ENSG00000181333|Vega:OTTHUMG00000167751 +341230 ASS1P13 HGNC:HGNC:763 +341276 OR10A2 HGNC:HGNC:8161|Ensembl:ENSG00000170790|Vega:OTTHUMG00000165739 +341277 OVCH2 HGNC:HGNC:29970|Ensembl:ENSG00000183378|Vega:OTTHUMG00000165418 +341315 PABPC1P4 MIM:604681|HGNC:HGNC:8563 +341333 HNRNPA1P70 HGNC:HGNC:48800 +341346 SMCO2 HGNC:HGNC:34448|Ensembl:ENSG00000165935|Vega:OTTHUMG00000169205 +341350 OVCH1 HGNC:HGNC:23080|Ensembl:ENSG00000187950|Vega:OTTHUMG00000167741 +341356 RPL31P50 HGNC:HGNC:36799 +341359 SYT10 HGNC:HGNC:19266|Ensembl:ENSG00000110975|Vega:OTTHUMG00000169269 +341378 LOC341378 - +341392 ACSM4 MIM:614360|HGNC:HGNC:32016|Ensembl:ENSG00000215009|Vega:OTTHUMG00000154975 +341405 ANKRD33 HGNC:HGNC:13788|Ensembl:ENSG00000167612|Vega:OTTHUMG00000169506 +341416 OR6C2 HGNC:HGNC:15436|Ensembl:ENSG00000179695|Vega:OTTHUMG00000169957 +341418 OR6C4 HGNC:HGNC:19632|Ensembl:ENSG00000179626|Vega:OTTHUMG00000169959 +341457 PPIAP8 HGNC:HGNC:9271 +341469 MRPS7P2 HGNC:HGNC:29784 +341511 RPL23AP14 HGNC:HGNC:21007 +341567 H1FNT HGNC:HGNC:24893|Ensembl:ENSG00000187166|Vega:OTTHUMG00000169904 +341568 OR8S1 HGNC:HGNC:19628|Ensembl:ENSG00000197376|Vega:OTTHUMG00000170021 +341604 RPL35P7 HGNC:HGNC:35740 +341640 FREM2 MIM:608945|HGNC:HGNC:25396|Ensembl:ENSG00000150893|Vega:OTTHUMG00000016759 +341674 RPL5P31 HGNC:HGNC:42036 +341676 NEK5 MIM:616731|HGNC:HGNC:7748|Ensembl:ENSG00000197168|Vega:OTTHUMG00000016957 +341689 CTAGE16P HGNC:HGNC:41967 +341757 MRPS31P2 HGNC:HGNC:39252 +341784 EIF4A1P7 HGNC:HGNC:37926 +341799 OR6S1 HGNC:HGNC:15363|Ensembl:ENSG00000181803|Vega:OTTHUMG00000171010 +341880 SLC35F4 HGNC:HGNC:19845|Ensembl:ENSG00000151812|Vega:OTTHUMG00000171317 +341883 LRRC9 HGNC:HGNC:19848|Ensembl:ENSG00000131951|Vega:OTTHUMG00000028948 +341947 COX8C MIM:616855|HGNC:HGNC:24382|Ensembl:ENSG00000187581|Vega:OTTHUMG00000171279 +341965 VDAC3P1 HGNC:HGNC:20722 +342035 GLDN MIM:608603|HGNC:HGNC:29514|Ensembl:ENSG00000186417|Vega:OTTHUMG00000131746 +342096 GOLGA6A MIM:610288|HGNC:HGNC:13567|Ensembl:ENSG00000159289|Vega:OTTHUMG00000173035 +342125 TMC3 MIM:617196|HGNC:HGNC:22995|Ensembl:ENSG00000188869|Vega:OTTHUMG00000172314 +342132 ZNF774 HGNC:HGNC:33108|Ensembl:ENSG00000196391|Vega:OTTHUMG00000172359 +342184 FMN1 MIM:136535|HGNC:HGNC:3768|Ensembl:ENSG00000248905|Vega:OTTHUMG00000172201 +342293 LOC342293 - +342346 C16orf96 HGNC:HGNC:40031|Ensembl:ENSG00000205832|Vega:OTTHUMG00000176519 +342357 ZKSCAN2 HGNC:HGNC:25677|Ensembl:ENSG00000155592|Vega:OTTHUMG00000177180 +342358 CYCSP39 HGNC:HGNC:24412 +342371 ATXN1L MIM:614301|HGNC:HGNC:33279|Ensembl:ENSG00000224470|Vega:OTTHUMG00000176872 +342372 PKD1L3 MIM:607895|HGNC:HGNC:21716|Ensembl:ENSG00000277481|Vega:OTTHUMG00000166114 +342374 KRT18P18 HGNC:HGNC:33386 +342419 KRT8P22 HGNC:HGNC:33374 +342426 ZNF720P1 HGNC:HGNC:34505 +342443 LOC342443 - +342510 CD300E MIM:609801|HGNC:HGNC:28874|Ensembl:ENSG00000186407|Vega:OTTHUMG00000067605 +342527 SMTNL2 HGNC:HGNC:24764|Ensembl:ENSG00000188176|Vega:OTTHUMG00000132938 +342538 NACA2 MIM:609274|HGNC:HGNC:23290|Ensembl:ENSG00000253506|Vega:OTTHUMG00000132321 +342541 LOC342541 - +342574 KRT27 MIM:616676|HGNC:HGNC:30841|Ensembl:ENSG00000171446|Vega:OTTHUMG00000133371 +342618 SLFN14 MIM:614958|HGNC:HGNC:32689|Ensembl:ENSG00000236320|Vega:OTTHUMG00000179912 +342666 LRRC37A11P HGNC:HGNC:43815|Ensembl:ENSG00000214553 +342667 STAC2 HGNC:HGNC:23990|Ensembl:ENSG00000141750|Vega:OTTHUMG00000179039 +342705 PGDP1 HGNC:HGNC:8892 +342732 KRT8P5 HGNC:HGNC:31094 +342776 MRPS17P7 HGNC:HGNC:29735 +342784 LOC342784 - +342808 RPS2P6 HGNC:HGNC:25485 +342850 ANKRD62 HGNC:HGNC:35241|Ensembl:ENSG00000181626|Vega:OTTHUMG00000180673 +342865 VSTM2B HGNC:HGNC:33595|Ensembl:ENSG00000187135|Vega:OTTHUMG00000182002 +342892 ZNF850 HGNC:HGNC:27994|Ensembl:ENSG00000267041|Vega:OTTHUMG00000180899 +342897 NCCRP1 MIM:615901|HGNC:HGNC:33739|Ensembl:ENSG00000188505|Vega:OTTHUMG00000182802 +342898 SYCN HGNC:HGNC:18442|Ensembl:ENSG00000179751|Vega:OTTHUMG00000182803 +342900 LEUTX HGNC:HGNC:31953|Ensembl:ENSG00000213921|Vega:OTTHUMG00000170877 +342908 ZNF404 HGNC:HGNC:19417|Ensembl:ENSG00000176222|Vega:OTTHUMG00000182206 +342909 ZNF284 HGNC:HGNC:13078|Ensembl:ENSG00000186026|Vega:OTTHUMG00000182312 +342918 C19orf81 HGNC:HGNC:40041|Ensembl:ENSG00000235034|Vega:OTTHUMG00000154593 +342926 ZNF677 HGNC:HGNC:28730|Ensembl:ENSG00000197928|Vega:OTTHUMG00000182890 +342931 RFPL4A MIM:612601|HGNC:HGNC:16449|Ensembl:ENSG00000223638|Vega:OTTHUMG00000165449 +342933 ZSCAN5B HGNC:HGNC:34246|Ensembl:ENSG00000197213|Vega:OTTHUMG00000181827 +342945 ZSCAN22 MIM:165260|HGNC:HGNC:4929|Ensembl:ENSG00000182318|Vega:OTTHUMG00000183463 +342977 NANOS3 MIM:608229|HGNC:HGNC:22048|Ensembl:ENSG00000187556|Vega:OTTHUMG00000181850 +342979 PALM3 HGNC:HGNC:33274|Ensembl:ENSG00000187867|Vega:OTTHUMG00000181991 +342994 RPL34P34 HGNC:HGNC:35848 +343035 RD3 MIM:180040|HGNC:HGNC:19689|Ensembl:ENSG00000198570|Vega:OTTHUMG00000037002 +343045 CYCSP51 HGNC:HGNC:24383 +343052 LOC343052 Ensembl:ENSG00000231827 +343066 AADACL4 HGNC:HGNC:32038|Ensembl:ENSG00000204518|Vega:OTTHUMG00000001889 +343068 PRAMEF5 HGNC:HGNC:27995|Ensembl:ENSG00000270601|Vega:OTTHUMG00000184604 +343069 HNRNPCL1 HGNC:HGNC:29295|Ensembl:ENSG00000179172|Vega:OTTHUMG00000001931 +343070 PRAMEF9 HGNC:HGNC:27996|Ensembl:ENSG00000204505|Vega:OTTHUMG00000189239 +343071 PRAMEF10 HGNC:HGNC:27997|Ensembl:ENSG00000187545|Vega:OTTHUMG00000001981 +343099 CCDC18 HGNC:HGNC:30370|Ensembl:ENSG00000122483|Vega:OTTHUMG00000010598 +343165 LOC343165 - +343169 OR6F1 HGNC:HGNC:15027|Ensembl:ENSG00000169214|Vega:OTTHUMG00000040213 +343170 OR14K1 HGNC:HGNC:15025 +343171 OR2W3 MIM:616729|HGNC:HGNC:15021|Ensembl:ENSG00000238243|Vega:OTTHUMG00000040204 +343172 OR2T8 HGNC:HGNC:15020|Ensembl:ENSG00000177462|Vega:OTTHUMG00000040205 +343173 OR2T3 HGNC:HGNC:14727|Ensembl:ENSG00000196539|Vega:OTTHUMG00000040452 +343184 RPS2P11 HGNC:HGNC:36350 +343263 MYBPHL HGNC:HGNC:30434|Ensembl:ENSG00000221986|Vega:OTTHUMG00000012002 +343296 ADH5P2 HGNC:HGNC:22976 +343301 RPL10AP4 HGNC:HGNC:35873 +343326 KRT18P28 HGNC:HGNC:33397 +343332 FDPSP1 HGNC:HGNC:3632 +343338 GAPDHP20 HGNC:HGNC:37772 +343381 NBPF2P HGNC:HGNC:31987 +343406 OR10R2 HGNC:HGNC:14820|Ensembl:ENSG00000198965|Vega:OTTHUMG00000019632 +343409 OR10J8P HGNC:HGNC:19638 +343413 FCRL6 MIM:613562|HGNC:HGNC:31910|Ensembl:ENSG00000181036|Vega:OTTHUMG00000035351 +343450 KCNT2 MIM:610044|HGNC:HGNC:18866|Ensembl:ENSG00000162687|Vega:OTTHUMG00000035611 +343472 BARHL2 MIM:605212|HGNC:HGNC:954|Ensembl:ENSG00000143032|Vega:OTTHUMG00000010020 +343477 HSP90B3P HGNC:HGNC:12100 +343495 RPL6P2 HGNC:HGNC:35964 +343505 NBPF7 MIM:613997|HGNC:HGNC:31989 +343508 LOC343508 - +343515 ATP6V1E1P1 HGNC:HGNC:859 +343521 TCTEX1D4 MIM:611713|HGNC:HGNC:32315|Ensembl:ENSG00000188396|Vega:OTTHUMG00000008586 +343563 OR2T29 HGNC:HGNC:31253|Ensembl:ENSG00000182783|Vega:OTTHUMG00000040382 +343578 ARHGAP40 HGNC:HGNC:16226|Ensembl:ENSG00000124143 +343637 RSPO4 MIM:610573|HGNC:HGNC:16175|Ensembl:ENSG00000101282|Vega:OTTHUMG00000031651 +343641 TGM6 MIM:613900|HGNC:HGNC:16255|Ensembl:ENSG00000166948|Vega:OTTHUMG00000031692 +343702 XKR7 HGNC:HGNC:23062|Ensembl:ENSG00000260903|Vega:OTTHUMG00000032198 +343727 CYCSP42 HGNC:HGNC:2581 +343819 MRPL51P2 HGNC:HGNC:29724 +343851 RPS10P30 HGNC:HGNC:35593 +343901 MRPS18CP6 HGNC:HGNC:29747 +343930 MSGN1 MIM:612209|HGNC:HGNC:14907|Ensembl:ENSG00000151379|Vega:OTTHUMG00000159089 +343981 GLULP6 HGNC:HGNC:37990 +343990 KIAA1211L HGNC:HGNC:33454|Ensembl:ENSG00000196872|Vega:OTTHUMG00000153171 +344018 FIGLA MIM:608697|HGNC:HGNC:24669|Ensembl:ENSG00000183733|Vega:OTTHUMG00000153440 +344022 NOTO HGNC:HGNC:31839|Ensembl:ENSG00000214513|Vega:OTTHUMG00000164128 +344065 LOC344065 - +344148 NCKAP5 MIM:608789|HGNC:HGNC:29847|Ensembl:ENSG00000176771|Vega:OTTHUMG00000153573 +344167 FOXI3 MIM:612351|HGNC:HGNC:35123|Ensembl:ENSG00000214336|Vega:OTTHUMG00000155048 +344178 RPL5P7 HGNC:HGNC:36583 +344191 EVX2 MIM:142991|HGNC:HGNC:3507|Ensembl:ENSG00000174279|Vega:OTTHUMG00000154173 +344320 KRT8P10 HGNC:HGNC:33364 +344328 ST13P2 HGNC:HGNC:38716 +344332 FABP5P10 HGNC:HGNC:31066 +344371 SLC25A5P2 HGNC:HGNC:35470 +344382 LOC344382 - +344387 CDKL4 HGNC:HGNC:19287|Ensembl:ENSG00000205111|Vega:OTTHUMG00000133574 +344405 PRORSD1P HGNC:HGNC:34379|Ensembl:ENSG00000162997 +344423 RPS12P3 HGNC:HGNC:35500 +344454 AOX2P HGNC:HGNC:18450 +344462 KRT18P39 HGNC:HGNC:33408 +344471 RPL12P17 HGNC:HGNC:36263 +344558 SH3RF3 HGNC:HGNC:24699|Ensembl:ENSG00000172985|Vega:OTTHUMG00000153439 +344561 GPR148 HGNC:HGNC:23623|Ensembl:ENSG00000173302|Vega:OTTHUMG00000131655 +344593 LOC344593 - +344595 DUBR MIM:616619|HGNC:HGNC:48569|Ensembl:ENSG00000243701 +344653 ABCF2P1 HGNC:HGNC:48841 +344657 LRRIQ4 HGNC:HGNC:34298|Ensembl:ENSG00000188306|Vega:OTTHUMG00000164420 +344658 SAMD7 HGNC:HGNC:25394|Ensembl:ENSG00000187033|Vega:OTTHUMG00000158730 +344697 HNRNPA1P21 HGNC:HGNC:39539 +344709 CCDC75P1 HGNC:HGNC:42659 +344729 OR7E140P HGNC:HGNC:19561 +344741 HNRNPA1P20 HGNC:HGNC:39538 +344752 AADACL2 HGNC:HGNC:24427|Ensembl:ENSG00000197953|Vega:OTTHUMG00000155914 +344758 GPR149 HGNC:HGNC:23627|Ensembl:ENSG00000174948|Vega:OTTHUMG00000159131 +344760 VN2R1P HGNC:HGNC:30344 +344787 ZNF860 HGNC:HGNC:34513|Ensembl:ENSG00000197385|Vega:OTTHUMG00000155838 +344805 TMPRSS7 HGNC:HGNC:30846|Ensembl:ENSG00000176040|Vega:OTTHUMG00000157148 +344807 CD200R1L HGNC:HGNC:24665|Ensembl:ENSG00000206531|Vega:OTTHUMG00000159283 +344813 GSTO3P HGNC:HGNC:23065 +344838 PAQR9 MIM:614580|HGNC:HGNC:30131|Ensembl:ENSG00000188582|Vega:OTTHUMG00000159313 +344866 KRT18P17 HGNC:HGNC:33385 +344875 COL6A4P1 MIM:612397|HGNC:HGNC:33484|Ensembl:ENSG00000230524 +344887 NMRAL2P HGNC:HGNC:52332|Ensembl:ENSG00000171658 +344892 RTP2 MIM:609138|HGNC:HGNC:32486|Ensembl:ENSG00000198471|Vega:OTTHUMG00000156458 +344901 OSTN MIM:610280|HGNC:HGNC:29961|Ensembl:ENSG00000188729|Vega:OTTHUMG00000156190 +344905 ATP13A5 HGNC:HGNC:31789|Ensembl:ENSG00000187527|Vega:OTTHUMG00000156101 +344967 LOC344967 MIM:611963|Ensembl:ENSG00000205794 +344978 ACTN4P1 HGNC:HGNC:44028 +344988 SAR1AP3 HGNC:HGNC:32317 +345016 PES1P1 HGNC:HGNC:44058 +345041 HSPD1P5 HGNC:HGNC:5266 +345051 LOC345051 Ensembl:ENSG00000250673|Vega:OTTHUMG00000161438 +345062 PRSS48 HGNC:HGNC:24635|Ensembl:ENSG00000189099|Vega:OTTHUMG00000161673 +345079 SOWAHB HGNC:HGNC:32958|Ensembl:ENSG00000186212|Vega:OTTHUMG00000160876 +345193 LRIT3 MIM:615004|HGNC:HGNC:24783|Ensembl:ENSG00000183423|Vega:OTTHUMG00000132043 +345222 MSANTD1 HGNC:HGNC:33741|Ensembl:ENSG00000188981|Vega:OTTHUMG00000159977 +345258 BIN2P1 HGNC:HGNC:43660 +345274 SLC10A6 MIM:613366|HGNC:HGNC:30603|Ensembl:ENSG00000145283|Vega:OTTHUMG00000130596 +345275 HSD17B13 MIM:612127|HGNC:HGNC:18685|Ensembl:ENSG00000170509|Vega:OTTHUMG00000130602 +345430 KRT18P41 HGNC:HGNC:33411 +345456 PFN3 MIM:612812|HGNC:HGNC:18627|Ensembl:ENSG00000196570|Vega:OTTHUMG00000163408 +345462 ZNF879 HGNC:HGNC:37273|Ensembl:ENSG00000234284|Vega:OTTHUMG00000163596 +345471 LOC345471 - +345557 PLCXD3 MIM:617016|HGNC:HGNC:31822|Ensembl:ENSG00000182836|Vega:OTTHUMG00000162076 +345571 LOC345571 - +345576 LOC345576 - +345611 IRGM MIM:608212|HGNC:HGNC:29597|Ensembl:ENSG00000237693|Vega:OTTHUMG00000163647 +345630 FBLL1 HGNC:HGNC:35458 +345643 MCIDAS MIM:614086|HGNC:HGNC:40050|Ensembl:ENSG00000234602|Vega:OTTHUMG00000162600 +345645 PSMC1P4 HGNC:HGNC:39779 +345651 ACTBL2 MIM:614835|HGNC:HGNC:17780|Ensembl:ENSG00000169067|Vega:OTTHUMG00000162330 +345757 FAM174A HGNC:HGNC:24943|Ensembl:ENSG00000174132|Vega:OTTHUMG00000128726 +345778 MTX3 HGNC:HGNC:24812|Ensembl:ENSG00000177034|Vega:OTTHUMG00000162547 +345829 BTF3P10 HGNC:HGNC:38570 +345895 RSPH4A MIM:612647|HGNC:HGNC:21558|Ensembl:ENSG00000111834|Vega:OTTHUMG00000015444 +345930 ECT2L HGNC:HGNC:21118|Ensembl:ENSG00000203734|Vega:OTTHUMG00000015679 +346007 EYS MIM:612424|HGNC:HGNC:21555|Ensembl:ENSG00000188107|Vega:OTTHUMG00000014971 +346085 GAPDHP72 HGNC:HGNC:22955 +346116 MRPL42P2 HGNC:HGNC:29711 +346157 ZNF391 HGNC:HGNC:18779|Ensembl:ENSG00000124613|Vega:OTTHUMG00000014477 +346171 ZFP57 MIM:612192|HGNC:HGNC:18791|Ensembl:ENSG00000204644|Vega:OTTHUMG00000031158 +346288 SEPT14 MIM:612140|HGNC:HGNC:33280|Ensembl:ENSG00000154997|Vega:OTTHUMG00000129341 +346296 LOC346296 - +346329 LOC346329 - +346389 MACC1 MIM:612646|HGNC:HGNC:30215|Ensembl:ENSG00000183742|Vega:OTTHUMG00000128415 +346470 MRPL42P4 HGNC:HGNC:29713 +346517 OR6V1 HGNC:HGNC:15090|Ensembl:ENSG00000225781|Vega:OTTHUMG00000158385 +346524 OR2Q1P HGNC:HGNC:8273 +346525 OR2A12 HGNC:HGNC:15082|Ensembl:ENSG00000221858|Vega:OTTHUMG00000157996 +346528 OR2A1 HGNC:HGNC:8229|Ensembl:ENSG00000221970|Vega:OTTHUMG00000158005 +346547 ERVFC1-1 HGNC:HGNC:38137 +346562 GNAT3 MIM:139395|HGNC:HGNC:22800|Ensembl:ENSG00000214415|Vega:OTTHUMG00000155401 +346606 MOGAT3 MIM:610184|HGNC:HGNC:23249|Ensembl:ENSG00000106384|Vega:OTTHUMG00000023328 +346653 FAM71F2 HGNC:HGNC:27998|Ensembl:ENSG00000205085 +346673 STRA8 MIM:609987|HGNC:HGNC:30653|Ensembl:ENSG00000146857|Vega:OTTHUMG00000155415 +346689 KLRG2 HGNC:HGNC:24778|Ensembl:ENSG00000188883|Vega:OTTHUMG00000157705 +346702 PRSS51 HGNC:HGNC:37321 +346708 OR7E8P HGNC:HGNC:8458 +346711 MRPL49P2 HGNC:HGNC:29718 +346950 RPL37P6 HGNC:HGNC:31080 +346990 H2AFZP2 HGNC:HGNC:32279 +347028 AFG3L2P1 HGNC:HGNC:24169 +347051 SLC10A5 HGNC:HGNC:22981|Ensembl:ENSG00000253598|Vega:OTTHUMG00000164683 +347088 ADGRD2 HGNC:HGNC:18651|Ensembl:ENSG00000180264|Vega:OTTHUMG00000020652 +347097 LOC347097 - +347127 SPATA31D5P HGNC:HGNC:38602|Ensembl:ENSG00000240632 +347148 QRFP MIM:609795|HGNC:HGNC:29982|Ensembl:ENSG00000188710|Vega:OTTHUMG00000131663 +347168 OR1J1 HGNC:HGNC:8208|Ensembl:ENSG00000136834|Vega:OTTHUMG00000020603 +347169 OR1B1 HGNC:HGNC:8181|Ensembl:ENSG00000280094|Vega:OTTHUMG00000020616 +347193 PES1P2 HGNC:HGNC:44059 +347240 KIF24 MIM:613747|HGNC:HGNC:19916|Ensembl:ENSG00000186638|Vega:OTTHUMG00000019810 +347252 IGFBPL1 MIM:610413|HGNC:HGNC:20081|Ensembl:ENSG00000137142|Vega:OTTHUMG00000019937 +347265 KRT8P11 HGNC:HGNC:31058 +347273 CAVIN4 HGNC:HGNC:33742|Ensembl:ENSG00000170681|Vega:OTTHUMG00000020368 +347275 BAATP1 HGNC:HGNC:34504 +347281 TOPORSLP1 HGNC:HGNC:50276 +347292 RPL36P14 HGNC:HGNC:35734 +347333 KRT8P14 HGNC:HGNC:33366 +347344 ZNF81 MIM:314998|HGNC:HGNC:13156|Ensembl:ENSG00000197779|Vega:OTTHUMG00000021462 +347359 BMP2KL HGNC:HGNC:17080 +347363 KIF4CP HGNC:HGNC:13340 +347365 ITIH6 HGNC:HGNC:28907|Ensembl:ENSG00000102313|Vega:OTTHUMG00000021634 +347376 H3F3AP5 HGNC:HGNC:42981 +347381 LOC347381 - +347402 NLRP3P1 HGNC:HGNC:29886 +347404 LANCL3 HGNC:HGNC:24767|Ensembl:ENSG00000147036|Vega:OTTHUMG00000033177 +347411 MPC1L HGNC:HGNC:44205|Ensembl:ENSG00000238205|Vega:OTTHUMG00000024105 +347422 LOC347422 - +347442 DCAF8L2 HGNC:HGNC:31811|Ensembl:ENSG00000189186|Vega:OTTHUMG00000021305 +347454 SOWAHD HGNC:HGNC:32960|Ensembl:ENSG00000187808|Vega:OTTHUMG00000159606 +347468 OR13H1 HGNC:HGNC:14755|Ensembl:ENSG00000171054|Vega:OTTHUMG00000022411 +347475 CCDC160 HGNC:HGNC:37286|Ensembl:ENSG00000203952|Vega:OTTHUMG00000164183 +347487 CXorf66 HGNC:HGNC:33743|Ensembl:ENSG00000203933|Vega:OTTHUMG00000022539 +347509 RPL7L1P11 HGNC:HGNC:39493 +347516 DGAT2L6 MIM:300926|HGNC:HGNC:23250|Ensembl:ENSG00000184210|Vega:OTTHUMG00000021774 +347517 RAB41 HGNC:HGNC:18293|Ensembl:ENSG00000147127|Vega:OTTHUMG00000021772 +347527 ARSH MIM:300586|HGNC:HGNC:32488|Ensembl:ENSG00000205667|Vega:OTTHUMG00000159612 +347541 MAGEB5 MIM:300466|HGNC:HGNC:23795|Ensembl:ENSG00000188408|Vega:OTTHUMG00000021288 +347544 RPL18AP16 HGNC:HGNC:36288 +347549 CENPVL3 HGNC:HGNC:43880 +347584 TSPY11P HGNC:HGNC:23903 +347587 MRPL57P10 HGNC:HGNC:23965 +347598 RBMY2DP HGNC:HGNC:23259 +347613 PARP4P1 HGNC:HGNC:18500 +347673 EIF2S2P2 HGNC:HGNC:24654 +347674 LOC347674 - +347675 EIF2S2P5 HGNC:HGNC:37793 +347686 SNORD64 HGNC:HGNC:32725|Ensembl:ENSG00000276610 +347687 GNG5P2 HGNC:HGNC:24826 +347688 TUBB8 MIM:616768|HGNC:HGNC:20773|Ensembl:ENSG00000261456|Vega:OTTHUMG00000174803 +347689 SOX2-OT MIM:616338|HGNC:HGNC:20209 +347694 ECEL1P2 HGNC:HGNC:14019|Ensembl:ENSG00000244280 +347701 S100A11P2 HGNC:HGNC:37840 +347702 MRPS36P4 HGNC:HGNC:29774 +347703 MRPS36P5 HGNC:HGNC:29775 +347704 MRPS36P3 HGNC:HGNC:29773 +347705 MRPS36P1 HGNC:HGNC:29771 +347706 MRPS36P2 HGNC:HGNC:29772 +347707 MRPS36P6 HGNC:HGNC:29776 +347713 DFNA42 HGNC:HGNC:20791 +347716 USP32P3 HGNC:HGNC:43576 +347717 SRP68P3 HGNC:HGNC:30428 +347720 COTL1P2 HGNC:HGNC:24322 +347730 LRRTM1 MIM:610867|HGNC:HGNC:19408|Ensembl:ENSG00000162951|Vega:OTTHUMG00000130021 +347731 LRRTM3 MIM:610869|HGNC:HGNC:19410|Ensembl:ENSG00000198739|Vega:OTTHUMG00000018332 +347732 CATSPER3 MIM:609120|HGNC:HGNC:20819|Ensembl:ENSG00000152705|Vega:OTTHUMG00000129137 +347733 TUBB2B MIM:612850|HGNC:HGNC:30829|Ensembl:ENSG00000137285|Vega:OTTHUMG00000014143 +347734 SLC35B2 MIM:610788|HGNC:HGNC:16872|Ensembl:ENSG00000157593|Vega:OTTHUMG00000014760 +347735 SERINC2 MIM:614549|HGNC:HGNC:23231|Ensembl:ENSG00000168528|Vega:OTTHUMG00000003796 +347736 NME9 HGNC:HGNC:21343|Ensembl:ENSG00000181322|Vega:OTTHUMG00000159823 +347737 DFNA31 MIM:608645|HGNC:HGNC:2803 +347741 OTOP3 MIM:607828|HGNC:HGNC:19658|Ensembl:ENSG00000182938|Vega:OTTHUMG00000179216 +347744 C6orf52 HGNC:HGNC:20881|Ensembl:ENSG00000137434|Vega:OTTHUMG00000014240 +347745 PWAR4 HGNC:HGNC:29998 +347746 PWARSN HGNC:HGNC:30001 +347747 HPCQTL19 MIM:607592 +347853 TBX10 MIM:604648|HGNC:HGNC:11593|Ensembl:ENSG00000167800|Vega:OTTHUMG00000167291 +347862 GATD1 HGNC:HGNC:26616|Ensembl:ENSG00000177225|Vega:OTTHUMG00000133315 +347894 MRPL2P1 HGNC:HGNC:29698 +347902 AMIGO2 MIM:615690|HGNC:HGNC:24073|Ensembl:ENSG00000139211|Vega:OTTHUMG00000169616 +347918 EP400NL HGNC:HGNC:26602|Ensembl:ENSG00000185684 +347933 NLRP9P1 HGNC:HGNC:29888 +348013 TMEM255B HGNC:HGNC:28297|Ensembl:ENSG00000184497|Vega:OTTHUMG00000017398 +348021 LINC00442 HGNC:HGNC:42779|Ensembl:ENSG00000232685 +348093 RBPMS2 HGNC:HGNC:19098|Ensembl:ENSG00000166831|Vega:OTTHUMG00000172423 +348094 ANKDD1A HGNC:HGNC:28002|Ensembl:ENSG00000166839|Vega:OTTHUMG00000133051 +348110 ARPIN MIM:615543|HGNC:HGNC:28782|Ensembl:ENSG00000242498|Vega:OTTHUMG00000154515 +348120 LINC01193 HGNC:HGNC:28003|Ensembl:ENSG00000258710 +348156 PKD1P5 HGNC:HGNC:30069 +348158 ACSM2B MIM:614359|HGNC:HGNC:30931|Ensembl:ENSG00000066813|Vega:OTTHUMG00000131555 +348174 CLEC18A MIM:616571|HGNC:HGNC:30388|Ensembl:ENSG00000157322|Vega:OTTHUMG00000137574 +348180 CTU2 MIM:617057|HGNC:HGNC:28005|Ensembl:ENSG00000174177|Vega:OTTHUMG00000173417 +348210 LOC348210 - +348235 SKA2 MIM:616674|HGNC:HGNC:28006|Ensembl:ENSG00000182628|Vega:OTTHUMG00000179361 +348249 CCL15-CCL14 HGNC:HGNC:44436 +348254 CCDC144CP HGNC:HGNC:29073 +348262 MCRIP1 MIM:616514|HGNC:HGNC:28007|Ensembl:ENSG00000225663|Vega:OTTHUMG00000177915 +348303 SELENOV MIM:607919|HGNC:HGNC:30399|Ensembl:ENSG00000186838|Vega:OTTHUMG00000166446 +348327 ZNF530 HGNC:HGNC:29297|Ensembl:ENSG00000183647|Vega:OTTHUMG00000183469 +348378 FAM159A HGNC:HGNC:28757|Ensembl:ENSG00000182183|Vega:OTTHUMG00000008330 +348487 FAM131C HGNC:HGNC:26717|Ensembl:ENSG00000185519|Vega:OTTHUMG00000009525 +348567 TERF1P1 HGNC:HGNC:16733 +348645 C22orf34 HGNC:HGNC:28010|Ensembl:ENSG00000188511 +348654 GEN1 MIM:612449|HGNC:HGNC:26881|Ensembl:ENSG00000178295|Vega:OTTHUMG00000121173 +348738 C2orf48 HGNC:HGNC:26322 +348751 FTCDNL1 MIM:614308|HGNC:HGNC:48661|Ensembl:ENSG00000226124|Vega:OTTHUMG00000154481 +348761 SPATA3-AS1 HGNC:HGNC:28013|Ensembl:ENSG00000238062 +348793 WDR53 MIM:615110|HGNC:HGNC:28786|Ensembl:ENSG00000185798|Vega:OTTHUMG00000155572 +348801 LNP1 HGNC:HGNC:28014|Ensembl:ENSG00000206535|Vega:OTTHUMG00000159082 +348807 CFAP100 HGNC:HGNC:26842|Ensembl:ENSG00000163885|Vega:OTTHUMG00000162691 +348808 NPHP3-AS1 HGNC:HGNC:24129|Ensembl:ENSG00000248724 +348825 TPRXL MIM:611167|HGNC:HGNC:32178|Ensembl:ENSG00000180438 +348840 ANKRD18DP HGNC:HGNC:28016|Ensembl:ENSG00000226435 +348910 RAF1P1 HGNC:HGNC:9830 +348926 FAM86EP HGNC:HGNC:28017|Ensembl:ENSG00000251669 +348932 SLC6A18 MIM:610300|HGNC:HGNC:26441|Ensembl:ENSG00000164363|Vega:OTTHUMG00000090356 +348938 NIPAL4 MIM:609383|HGNC:HGNC:28018|Ensembl:ENSG00000172548|Vega:OTTHUMG00000163497 +348958 LOC348958 - +348980 HCN1 MIM:602780|HGNC:HGNC:4845|Ensembl:ENSG00000164588|Vega:OTTHUMG00000131155 +348995 NUP43 MIM:608141|HGNC:HGNC:21182|Ensembl:ENSG00000120253|Vega:OTTHUMG00000015795 +349075 ZNF713 MIM:616181|HGNC:HGNC:22043|Ensembl:ENSG00000178665|Vega:OTTHUMG00000156175 +349114 LINC00265 HGNC:HGNC:28019 +349136 WDR86 HGNC:HGNC:28020|Ensembl:ENSG00000187260|Vega:OTTHUMG00000150764 +349149 GJC3 MIM:611925|HGNC:HGNC:17495|Ensembl:ENSG00000176402|Vega:OTTHUMG00000156649 +349152 DPY19L2P2 HGNC:HGNC:21764|Ensembl:ENSG00000170629 +349158 CYCSP20 HGNC:HGNC:24394 +349160 LOC349160 Ensembl:ENSG00000234352 +349196 LINC00965 HGNC:HGNC:28022 +349198 CYCSP3 HGNC:HGNC:24395 +349334 FOXD4L4 MIM:611085|HGNC:HGNC:23762|Ensembl:ENSG00000184659|Vega:OTTHUMG00000013337 +349372 NANOGP10 HGNC:HGNC:23108 +349386 NANOGP9 HGNC:HGNC:23107 +349391 CYCSP44 HGNC:HGNC:24418 +349408 TLR8-AS1 HGNC:HGNC:40720|Ensembl:ENSG00000233338 +349448 TUBB1P1 HGNC:HGNC:23982 +349565 NMNAT3 MIM:608702|HGNC:HGNC:20989|Ensembl:ENSG00000163864|Vega:OTTHUMG00000159951 +349633 PLET1 MIM:611904|HGNC:HGNC:30053|Ensembl:ENSG00000188771|Vega:OTTHUMG00000167189 +349667 RTN4RL2 MIM:610462|HGNC:HGNC:23053|Ensembl:ENSG00000186907|Vega:OTTHUMG00000167028 +349814 VENTXP3 HGNC:HGNC:30902 +349842 MRPS18CP4 HGNC:HGNC:29745 +350297 MRPS21P8 HGNC:HGNC:29755 +350383 GPR142 MIM:609046|HGNC:HGNC:20088|Ensembl:ENSG00000257008|Vega:OTTHUMG00000178581 +351143 MRPL50P1 HGNC:HGNC:29719 +351449 MRPS31P1 HGNC:HGNC:29763 +351773 MRPL51P1 HGNC:HGNC:29723 +352290 MRPS23P1 HGNC:HGNC:29758 +352852 CYCSP45 HGNC:HGNC:24419 +352887 GYG2P1 HGNC:HGNC:4701|Ensembl:ENSG00000206159 +352896 GPR143P HGNC:HGNC:18499 +352905 CTBP2P1 HGNC:HGNC:23940 +352909 DNAAF3 MIM:614566|HGNC:HGNC:30492|Ensembl:ENSG00000167646|Vega:OTTHUMG00000128547 +352954 GATS HGNC:HGNC:29954|Ensembl:ENSG00000239521|Vega:OTTHUMG00000155289 +352956 MMVP2 MIM:607829|HGNC:HGNC:19145 +352957 MICF HGNC:HGNC:16801 +352961 HCG26 HGNC:HGNC:29671 +352962 HLA-V HGNC:HGNC:23482 +352963 HLA-P HGNC:HGNC:21196 +352964 HLA-T HGNC:HGNC:23478 +352965 HLA-U HGNC:HGNC:23477 +352966 HLA-W HGNC:HGNC:23425 +352967 MICG HGNC:HGNC:16802 +352990 HCP5B HGNC:HGNC:30984 +352999 C6orf58 HGNC:HGNC:20960|Ensembl:ENSG00000184530|Vega:OTTHUMG00000015530 +353000 HCGVIII-2 - +353001 HCG4P3 HGNC:HGNC:22922 +353002 HCG4P4 HGNC:HGNC:22924 +353003 HCG4P5 HGNC:HGNC:22925 +353004 HCG4P7 HGNC:HGNC:22926 +353005 HCG4P8 HGNC:HGNC:22927 +353007 3.8-1.2 - +353008 3.8-1.3 - +353009 3.8-1.4 - +353010 3.8-1.5 - +353013 RPL7AP7 HGNC:HGNC:21395 +353014 HCG4P9 HGNC:HGNC:22928 +353019 HCG9P5 HGNC:HGNC:30983 +353020 HCG4P11 HGNC:HGNC:22930 +353088 ZNF429 HGNC:HGNC:20817|Ensembl:ENSG00000197013|Vega:OTTHUMG00000182848 +353089 RAET1F HGNC:HGNC:16794 +353091 RAET1G MIM:609244|HGNC:HGNC:16795|Ensembl:ENSG00000203722|Vega:OTTHUMG00000015802 +353094 RAET1M HGNC:HGNC:16799 +353116 RILPL1 MIM:614092|HGNC:HGNC:26814|Ensembl:ENSG00000188026|Vega:OTTHUMG00000168686 +353124 EIG2 MIM:606972 +353125 HDLC3 MIM:607687 +353126 BMIQ10 MIM:607514 +353127 HDLCQ2 MIM:607053 +353128 AD8 MIM:607116 +353131 LCE1A MIM:612603|HGNC:HGNC:29459|Ensembl:ENSG00000186844|Vega:OTTHUMG00000012447 +353132 LCE1B MIM:612604|HGNC:HGNC:16611|Ensembl:ENSG00000196734|Vega:OTTHUMG00000014402 +353133 LCE1C MIM:612605|HGNC:HGNC:29464|Ensembl:ENSG00000197084|Vega:OTTHUMG00000012445 +353134 LCE1D MIM:612606|HGNC:HGNC:29465|Ensembl:ENSG00000172155|Vega:OTTHUMG00000012444 +353135 LCE1E MIM:612607|HGNC:HGNC:29466|Ensembl:ENSG00000186226|Vega:OTTHUMG00000012405 +353137 LCE1F MIM:612608|HGNC:HGNC:29467|Ensembl:ENSG00000240386|Vega:OTTHUMG00000012403 +353139 LCE2A MIM:612609|HGNC:HGNC:29469|Ensembl:ENSG00000187173|Vega:OTTHUMG00000012392 +353140 LCE2C MIM:612611|HGNC:HGNC:29460|Ensembl:ENSG00000187180|Vega:OTTHUMG00000012389 +353141 LCE2D MIM:612612|HGNC:HGNC:16518|Ensembl:ENSG00000187223|Vega:OTTHUMG00000014400 +353142 LCE3A MIM:612613|HGNC:HGNC:29461|Ensembl:ENSG00000185962|Vega:OTTHUMG00000012397 +353143 LCE3B MIM:612614|HGNC:HGNC:29462|Ensembl:ENSG00000187238|Vega:OTTHUMG00000012395 +353144 LCE3C MIM:612615|HGNC:HGNC:16612|Ensembl:ENSG00000244057|Vega:OTTHUMG00000014403 +353145 LCE3E MIM:612617|HGNC:HGNC:29463|Ensembl:ENSG00000185966|Vega:OTTHUMG00000012393 +353147 POROK4 MIM:607728 +353149 TBC1D26 HGNC:HGNC:28745|Ensembl:ENSG00000214946|Vega:OTTHUMG00000059071 +353163 CAP2P1 HGNC:HGNC:20142 +353164 TAS2R42 MIM:613966|HGNC:HGNC:18888|Ensembl:ENSG00000186136|Vega:OTTHUMG00000168567 +353173 ZLS MIM:135500 +353174 ZACN MIM:610935|HGNC:HGNC:29504|Ensembl:ENSG00000186919|Vega:OTTHUMG00000157186 +353189 SLCO4C1 MIM:609013|HGNC:HGNC:23612|Ensembl:ENSG00000173930|Vega:OTTHUMG00000162757 +353194 KRT16P6 HGNC:HGNC:50719 +353196 KRT16P5 HGNC:HGNC:37810 +353219 KAAG1 MIM:608211|HGNC:HGNC:21031|Ensembl:ENSG00000146049|Vega:OTTHUMG00000014354 +353238 PADI6 MIM:610363|HGNC:HGNC:20449|Ensembl:ENSG00000276747|Vega:OTTHUMG00000002372 +353267 FAM103A2P HGNC:HGNC:21234 +353274 ZNF445 HGNC:HGNC:21018|Ensembl:ENSG00000185219|Vega:OTTHUMG00000133042 +353288 KRT26 MIM:616675|HGNC:HGNC:30840|Ensembl:ENSG00000186393|Vega:OTTHUMG00000133370 +353293 SPG23 MIM:270750|HGNC:HGNC:21340 +353299 RGSL1 MIM:611012|HGNC:HGNC:18636|Ensembl:ENSG00000121446|Vega:OTTHUMG00000035217 +353322 ANKRD37 HGNC:HGNC:29593|Ensembl:ENSG00000186352|Vega:OTTHUMG00000160459 +353323 KRTAP12-2 HGNC:HGNC:20530|Ensembl:ENSG00000221864|Vega:OTTHUMG00000057636 +353324 SPATA12 MIM:609869|HGNC:HGNC:23221|Ensembl:ENSG00000186451|Vega:OTTHUMG00000158862 +353329 PSIP1P1 HGNC:HGNC:31132 +353332 KRTAP12-1 HGNC:HGNC:20529|Ensembl:ENSG00000187175|Vega:OTTHUMG00000057639 +353333 KRTAP10-10 HGNC:HGNC:22972|Ensembl:ENSG00000221859|Vega:OTTHUMG00000057631 +353345 GPR141 MIM:609045|HGNC:HGNC:19997|Ensembl:ENSG00000187037|Vega:OTTHUMG00000102105 +353347 DFNA53 MIM:609965|HGNC:HGNC:21402 +353355 ZNF233 HGNC:HGNC:30946|Ensembl:ENSG00000159915|Vega:OTTHUMG00000182354 +353376 TICAM2 MIM:608321|HGNC:HGNC:21354|Ensembl:ENSG00000243414|Vega:OTTHUMG00000162905 +353497 POLN MIM:610887|HGNC:HGNC:18870|Ensembl:ENSG00000130997|Vega:OTTHUMG00000090081 +353500 BMP8A HGNC:HGNC:21650|Ensembl:ENSG00000183682|Vega:OTTHUMG00000008394 +353511 PKD1P6 HGNC:HGNC:30070 +353512 PKD1P4 HGNC:HGNC:30068 +353513 VCY1B HGNC:HGNC:31751|Ensembl:ENSG00000129862|Vega:OTTHUMG00000036402 +353514 LILRA5 MIM:606047|HGNC:HGNC:16309|Ensembl:ENSG00000187116|Vega:OTTHUMG00000065357 +353515 XKRY2 HGNC:HGNC:23922 +359710 BPIFB3 MIM:615717|HGNC:HGNC:16178|Ensembl:ENSG00000186190|Vega:OTTHUMG00000032234 +359724 RNA18SP2 HGNC:HGNC:37658 +359729 MRPL57P2 HGNC:HGNC:29687 +359730 MRPL57P3 HGNC:HGNC:29688 +359731 MRPL57P7 HGNC:HGNC:29690 +359732 MRPL57P8 HGNC:HGNC:29691 +359733 MRPL57P9 HGNC:HGNC:29692 +359734 MRPL11P3 HGNC:HGNC:29695 +359735 MRPL14P1 HGNC:HGNC:29696 +359736 MRPL15P1 HGNC:HGNC:29697 +359737 MRPL20P1 HGNC:HGNC:29699 +359738 MRPL22P1 HGNC:HGNC:29700 +359739 MRPL3P1 HGNC:HGNC:29701 +359740 MRPL30P1 HGNC:HGNC:29702 +359741 MRPL32P1 HGNC:HGNC:29704 +359742 MRPL35P1 HGNC:HGNC:29705 +359743 MRPL35P2 HGNC:HGNC:29706 +359744 MRPL35P3 HGNC:HGNC:23731 +359745 MRPL35P4 HGNC:HGNC:29707 +359746 MRPL42P3 HGNC:HGNC:29712 +359747 MRPL45P1 HGNC:HGNC:29715 +359748 MRPL49P1 HGNC:HGNC:29717 +359749 MRPL50P2 HGNC:HGNC:29720 +359750 MRPL50P3 HGNC:HGNC:29721 +359751 MRPL50P4 HGNC:HGNC:29722 +359752 MRPL53P1 HGNC:HGNC:29725 +359753 MRPS10P1 HGNC:HGNC:29728 +359754 MRPS10P5 HGNC:HGNC:29729 +359755 MRPS15P1 HGNC:HGNC:29730 +359756 MRPS15P2 HGNC:HGNC:29731 +359757 MRPS17P3 HGNC:HGNC:29736 +359758 MRPS17P5 HGNC:HGNC:29737 +359759 MRPS17P6 HGNC:HGNC:29738 +359760 MRPS17P9 HGNC:HGNC:29739 +359761 MRPS18AP1 HGNC:HGNC:29740 +359762 MRPS18BP1 HGNC:HGNC:29741 +359763 MRPS18BP2 HGNC:HGNC:29742 +359764 MRPS18CP3 HGNC:HGNC:29744 +359765 MRPS18CP5 HGNC:HGNC:29746 +359766 MRPS21P2 HGNC:HGNC:29749 +359767 MRPS21P3 HGNC:HGNC:29750 +359768 MRPS21P4 HGNC:HGNC:29751 +359769 MRPS21P5 HGNC:HGNC:29752 +359770 MRPS21P6 HGNC:HGNC:29753 +359771 MRPS21P7 HGNC:HGNC:29754 +359772 MRPS21P9 HGNC:HGNC:29756 +359773 MRPS22P1 HGNC:HGNC:29757 +359774 DAP3P2 HGNC:HGNC:29762 +359775 MRPS33P2 HGNC:HGNC:29765 +359776 MRPS33P3 HGNC:HGNC:29766 +359777 MRPS33P4 HGNC:HGNC:29767 +359778 MRPS35P2 HGNC:HGNC:29769 +359779 MRPS35P3 HGNC:HGNC:29770 +359780 MRPS6P1 HGNC:HGNC:29780 +359781 MRPS6P2 HGNC:HGNC:29781 +359782 MRPS6P4 HGNC:HGNC:29782 +359783 MRPS7P1 HGNC:HGNC:29783 +359787 DPPA3 MIM:608408|HGNC:HGNC:19199|Ensembl:ENSG00000187569|Vega:OTTHUMG00000168434 +359791 MED14P1 HGNC:HGNC:2371 +359792 EIF4A1P2 HGNC:HGNC:23946 +359793 AGKP1 HGNC:HGNC:37661 +359794 TUSC2P1 HGNC:HGNC:23963 +359795 NEFLP1 HGNC:HGNC:37662 +359796 KDM5DP1 HGNC:HGNC:23976 +359797 MRPS5P4 HGNC:HGNC:29779 +359798 UBE2V1P3 HGNC:HGNC:23983 +359799 USP12PY HGNC:HGNC:23195 +359800 VDAC1P6 HGNC:HGNC:37481 +359802 MRPS10P2 HGNC:HGNC:29727 +359803 MRPS17P1 HGNC:HGNC:29734 +359804 DAP3P1 HGNC:HGNC:17624 +359805 PCNAP2 HGNC:HGNC:8733 +359806 PCNAP1 HGNC:HGNC:8732 +359809 PEG13 HGNC:HGNC:19969 +359817 MRPL30P2 HGNC:HGNC:29703 +359819 LOC359819 - +359821 MRPL42P5 HGNC:HGNC:29714 +359822 KCNIP4-IT1 HGNC:HGNC:29895|Ensembl:ENSG00000280650 +359825 PSORS9 MIM:607857|HGNC:HGNC:31013 +359844 PRDX2P1 HGNC:HGNC:30020 +359845 RFLNB MIM:615928|HGNC:HGNC:28705|Ensembl:ENSG00000183688|Vega:OTTHUMG00000132483 +359941 CDK4P1 HGNC:HGNC:19040 +359948 IRF2BP2 MIM:615332|HGNC:HGNC:21729|Ensembl:ENSG00000168264|Vega:OTTHUMG00000037981 +359996 SERBP1P2 HGNC:HGNC:23967 +359997 ATP5JP1 HGNC:HGNC:23933 +359998 CHRFAM7AP2 HGNC:HGNC:23937 +359999 CHRFAM7AP1 HGNC:HGNC:37766 +360001 IFNWP18 HGNC:HGNC:5450 +360002 TAF9P1 HGNC:HGNC:31743 +360003 TAF9P2 HGNC:HGNC:31744 +360008 GAPDHP17 HGNC:HGNC:37765 +360009 CYCSP49 HGNC:HGNC:23943 +360014 DLGAP5P1 HGNC:HGNC:23945 +360015 RFTN1P1 HGNC:HGNC:23971 +360016 CICP2 HGNC:HGNC:23935 +360017 CICP1 HGNC:HGNC:23936 +360018 PRRC2CP1 HGNC:HGNC:23949 +360019 KRT18P10 HGNC:HGNC:23962 +360020 PPP1R12BP2 HGNC:HGNC:23970 +360021 PPP1R12BP1 HGNC:HGNC:18498 +360022 PSIP1P2 HGNC:HGNC:23968 +360023 ZBTB41 HGNC:HGNC:24819|Ensembl:ENSG00000177888|Vega:OTTHUMG00000036275 +360024 GOLGA6L11P HGNC:HGNC:23958 +360025 GOLGA6L12P HGNC:HGNC:23959 +360026 GOLGA6L13P HGNC:HGNC:23960 +360027 GOLGA6L14P HGNC:HGNC:23961 +360028 TMEM167AP1 HGNC:HGNC:23956 +360029 FAM199YP HGNC:HGNC:23951 +360030 NANOGNB HGNC:HGNC:24958|Ensembl:ENSG00000205857|Vega:OTTHUMG00000165107 +360132 FKBP9P1 HGNC:HGNC:23568|Ensembl:ENSG00000176826 +360155 CYCSP52 HGNC:HGNC:24393|Ensembl:ENSG00000235700 +360156 CYCSP53 HGNC:HGNC:24404 +360157 CYCSP4 HGNC:HGNC:24413 +360158 CYCSP5 HGNC:HGNC:24416 +360159 CYCSP6 HGNC:HGNC:24421 +360160 CYCSP8 HGNC:HGNC:24423 +360163 CYCTP HGNC:HGNC:24424 +360165 NDUFA4P1 HGNC:HGNC:29835 +360166 CYCSP10 HGNC:HGNC:24384 +360167 CYCSP11 HGNC:HGNC:24385 +360168 CYCSP12 HGNC:HGNC:24386 +360170 CYCSP14 HGNC:HGNC:24388 +360171 CYCSP16 HGNC:HGNC:24389 +360172 CYCSP17 HGNC:HGNC:24390 +360173 CYCSP18 HGNC:HGNC:24391 +360174 CYCSP19 HGNC:HGNC:24392 +360175 CYCSP22 HGNC:HGNC:24396 +360176 CYCSP23 HGNC:HGNC:24397 +360177 CYCSP24 HGNC:HGNC:24398 +360178 CYCSP26 HGNC:HGNC:24400 +360179 CYCSP28 HGNC:HGNC:24402 +360180 CYCSP29 HGNC:HGNC:24403 +360181 CYCSP32 HGNC:HGNC:24406 +360182 CYCSP34 HGNC:HGNC:24408 +360183 CYCSP2 HGNC:HGNC:24410 +360184 CYCSP38 HGNC:HGNC:24411 +360185 CYCSP40 HGNC:HGNC:24414 +360186 CYCSP41 HGNC:HGNC:2580 +360187 CYCSP43 HGNC:HGNC:24417 +360188 CYCSP48 HGNC:HGNC:23942 +360200 TMPRSS9 MIM:610477|HGNC:HGNC:30079|Ensembl:ENSG00000178297|Vega:OTTHUMG00000180431 +360203 GLT6D1 MIM:613699|HGNC:HGNC:23671|Ensembl:ENSG00000204007|Vega:OTTHUMG00000020911 +360205 PRAC2 MIM:610787|HGNC:HGNC:30143|Ensembl:ENSG00000229637|Vega:OTTHUMG00000132085 +360219 GCRG224 MIM:610888 +360226 PRSS41 HGNC:HGNC:30715|Ensembl:ENSG00000215148 +360227 OTUD4P1 HGNC:HGNC:33912 +373071 AIS1 MIM:607836|HGNC:HGNC:16304 +373073 CLAM MIM:608027|HGNC:HGNC:20394 +373156 GSTK1 MIM:602321|HGNC:HGNC:16906|Ensembl:ENSG00000197448|Vega:OTTHUMG00000152637 +373159 STK19B HGNC:HGNC:21668 +373509 USP50 HGNC:HGNC:20079|Ensembl:ENSG00000170236|Vega:OTTHUMG00000167591 +373856 USP41 HGNC:HGNC:20070|Ensembl:ENSG00000161133|Vega:OTTHUMG00000151317 +373861 HILS1 MIM:608101|HGNC:HGNC:30616 +373863 DND1 MIM:609385|HGNC:HGNC:23799|Ensembl:ENSG00000256453|Vega:OTTHUMG00000129499 +374286 CDRT1 MIM:604596|HGNC:HGNC:14379|Ensembl:ENSG00000241322|Vega:OTTHUMG00000059074 +374291 NDUFS7 MIM:601825|HGNC:HGNC:7714|Ensembl:ENSG00000115286|Vega:OTTHUMG00000168077 +374308 PTCHD3 MIM:611791|HGNC:HGNC:24776|Ensembl:ENSG00000182077|Vega:OTTHUMG00000017860 +374354 NHLRC2 HGNC:HGNC:24731|Ensembl:ENSG00000196865|Vega:OTTHUMG00000019078 +374355 CCDC172 HGNC:HGNC:30524|Ensembl:ENSG00000182645|Vega:OTTHUMG00000019098 +374378 GALNT18 MIM:615136|HGNC:HGNC:30488|Ensembl:ENSG00000110328|Vega:OTTHUMG00000165707 +374383 NCR3LG1 MIM:613714|HGNC:HGNC:42400|Ensembl:ENSG00000188211|Vega:OTTHUMG00000165913 +374387 DKFZp779M0652 Ensembl:ENSG00000205106 +374393 FAM111B MIM:615584|HGNC:HGNC:24200|Ensembl:ENSG00000189057|Vega:OTTHUMG00000167279 +374395 TMEM179B HGNC:HGNC:33744|Ensembl:ENSG00000185475|Vega:OTTHUMG00000167611 +374403 TBC1D10C MIM:610831|HGNC:HGNC:24702|Ensembl:ENSG00000175463|Vega:OTTHUMG00000167139 +374407 DNAJB13 MIM:610263|HGNC:HGNC:30718|Ensembl:ENSG00000187726|Vega:OTTHUMG00000168093 +374443 LOC374443 Ensembl:ENSG00000256594 +374454 KRT77 MIM:611158|HGNC:HGNC:20411|Ensembl:ENSG00000189182|Vega:OTTHUMG00000169450 +374462 PTPRQ MIM:603317|HGNC:HGNC:9679|Ensembl:ENSG00000139304|Vega:OTTHUMG00000170171 +374470 C12orf42 HGNC:HGNC:24729|Ensembl:ENSG00000179088|Vega:OTTHUMG00000169988 +374491 TPTE2P6 HGNC:HGNC:42644 +374500 THSD1P1 HGNC:HGNC:31375 +374569 ASPG HGNC:HGNC:20123|Ensembl:ENSG00000166183|Vega:OTTHUMG00000170045 +374618 TEX9 HGNC:HGNC:29585|Ensembl:ENSG00000151575|Vega:OTTHUMG00000132035 +374650 GOLGA6L5P HGNC:HGNC:30472 +374654 KIF7 MIM:611254|HGNC:HGNC:30497|Ensembl:ENSG00000166813|Vega:OTTHUMG00000157177 +374655 ZNF710 HGNC:HGNC:25352|Ensembl:ENSG00000140548|Vega:OTTHUMG00000149812 +374659 HDDC3 HGNC:HGNC:30522|Ensembl:ENSG00000184508|Vega:OTTHUMG00000141260 +374666 WASH3P HGNC:HGNC:24362 +374677 WASH4P HGNC:HGNC:14126 +374739 TEPP MIM:610264|HGNC:HGNC:33745|Ensembl:ENSG00000159648|Vega:OTTHUMG00000133463 +374768 SPEM1 MIM:615116|HGNC:HGNC:32429|Ensembl:ENSG00000181323|Vega:OTTHUMG00000178189 +374786 EFCAB5 HGNC:HGNC:24801|Ensembl:ENSG00000176927|Vega:OTTHUMG00000179743 +374819 LRRC37A3 MIM:616557|HGNC:HGNC:32427|Ensembl:ENSG00000176809|Vega:OTTHUMG00000132307 +374860 ANKRD30B MIM:616565|HGNC:HGNC:24165|Ensembl:ENSG00000180777|Vega:OTTHUMG00000178841 +374864 CCDC178 HGNC:HGNC:29588|Ensembl:ENSG00000166960|Vega:OTTHUMG00000132279 +374868 ATP9B MIM:614446|HGNC:HGNC:13541|Ensembl:ENSG00000166377|Vega:OTTHUMG00000132898 +374872 C19orf35 HGNC:HGNC:24793|Ensembl:ENSG00000188305|Vega:OTTHUMG00000178460 +374875 HSD11B1L HGNC:HGNC:30419|Ensembl:ENSG00000167733|Vega:OTTHUMG00000178586 +374877 TEX45 HGNC:HGNC:24745|Ensembl:ENSG00000198723|Vega:OTTHUMG00000157183 +374879 ZNF699 MIM:609571|HGNC:HGNC:24750|Ensembl:ENSG00000196110|Vega:OTTHUMG00000179941 +374882 TMEM205 MIM:613771|HGNC:HGNC:29631|Ensembl:ENSG00000105518|Vega:OTTHUMG00000182021 +374887 YJEFN3 HGNC:HGNC:24785|Ensembl:ENSG00000250067|Vega:OTTHUMG00000162251 +374890 LINC01785 HGNC:HGNC:25060|Ensembl:ENSG00000268038 +374897 SBSN MIM:609969|HGNC:HGNC:24950|Ensembl:ENSG00000189001|Vega:OTTHUMG00000048102 +374899 ZNF829 HGNC:HGNC:34032|Ensembl:ENSG00000185869|Vega:OTTHUMG00000048161 +374900 ZNF568 MIM:617566|HGNC:HGNC:25392|Ensembl:ENSG00000198453|Vega:OTTHUMG00000048160 +374907 B3GNT8 MIM:615357|HGNC:HGNC:24139|Ensembl:ENSG00000177191|Vega:OTTHUMG00000182749 +374918 IGFL1 MIM:610544|HGNC:HGNC:24093|Ensembl:ENSG00000188293|Vega:OTTHUMG00000182501 +374920 C19orf68 HGNC:HGNC:34495|Ensembl:ENSG00000185453 +374928 ZNF773 HGNC:HGNC:30487|Ensembl:ENSG00000152439|Vega:OTTHUMG00000183403 +374946 DRAXIN MIM:612682|HGNC:HGNC:25054|Ensembl:ENSG00000162490|Vega:OTTHUMG00000002227 +374955 SPATA21 HGNC:HGNC:28026|Ensembl:ENSG00000187144|Vega:OTTHUMG00000002312 +374969 SVBP HGNC:HGNC:29204|Ensembl:ENSG00000177868|Vega:OTTHUMG00000007566 +374973 TEX38 HGNC:HGNC:29589|Ensembl:ENSG00000186118|Vega:OTTHUMG00000007991 +374977 MROH7 HGNC:HGNC:24802|Ensembl:ENSG00000184313|Vega:OTTHUMG00000009890 +374986 MIGA1 MIM:616773|HGNC:HGNC:24741|Ensembl:ENSG00000180488|Vega:OTTHUMG00000009766 +374987 NEXN-AS1 HGNC:HGNC:31983|Ensembl:ENSG00000235927 +375027 S100A7P2 HGNC:HGNC:21656 +375033 PEAR1 MIM:610278|HGNC:HGNC:33631|Ensembl:ENSG00000187800|Vega:OTTHUMG00000041293 +375035 SFT2D2 HGNC:HGNC:25140|Ensembl:ENSG00000213064|Vega:OTTHUMG00000034650 +375056 MIA3 MIM:613455|HGNC:HGNC:24008|Ensembl:ENSG00000154305|Vega:OTTHUMG00000037543 +375057 STUM HGNC:HGNC:30491|Ensembl:ENSG00000203685|Vega:OTTHUMG00000037583 +375061 FAM89A HGNC:HGNC:25057|Ensembl:ENSG00000182118|Vega:OTTHUMG00000037960 +375133 PI4KAP2 HGNC:HGNC:33577|Ensembl:ENSG00000183506 +375189 PFN4 HGNC:HGNC:31103|Ensembl:ENSG00000176732|Vega:OTTHUMG00000090816 +375190 FAM228B HGNC:HGNC:24736|Ensembl:ENSG00000219626|Vega:OTTHUMG00000151901 +375196 LOC375196 Ensembl:ENSG00000269210 +375248 ANKRD36 HGNC:HGNC:24079|Ensembl:ENSG00000135976|Vega:OTTHUMG00000155256 +375260 WASH2P HGNC:HGNC:33145|Ensembl:ENSG00000146556 +375287 RBM43 HGNC:HGNC:24790|Ensembl:ENSG00000184898|Vega:OTTHUMG00000131866 +375295 LINC01116 HGNC:HGNC:49259 +375298 CERKL MIM:608381|HGNC:HGNC:21699|Ensembl:ENSG00000188452|Vega:OTTHUMG00000154315 +375307 CATIP HGNC:HGNC:25062|Ensembl:ENSG00000158428|Vega:OTTHUMG00000133106 +375316 RBM44 HGNC:HGNC:24756|Ensembl:ENSG00000177483|Vega:OTTHUMG00000152937 +375318 AQP12A MIM:609789|HGNC:HGNC:19941|Ensembl:ENSG00000184945|Vega:OTTHUMG00000183906 +375323 LHFPL4 MIM:610240|HGNC:HGNC:29568|Ensembl:ENSG00000156959|Vega:OTTHUMG00000155066 +375337 TOPAZ1 MIM:614412|HGNC:HGNC:24746|Ensembl:ENSG00000173769|Vega:OTTHUMG00000156172 +375341 C3orf62 HGNC:HGNC:24771|Ensembl:ENSG00000188315|Vega:OTTHUMG00000156819 +375346 TMEM110 MIM:617189|HGNC:HGNC:30526|Ensembl:ENSG00000213533|Vega:OTTHUMG00000150346 +375350 COPS8P2 HGNC:HGNC:45270 +375387 NRROS MIM:615322|HGNC:HGNC:24613|Ensembl:ENSG00000174004|Vega:OTTHUMG00000155569 +375444 C5orf34 HGNC:HGNC:24738|Ensembl:ENSG00000172244|Vega:OTTHUMG00000131151 +375449 MAST4 HGNC:HGNC:19037|Ensembl:ENSG00000069020|Vega:OTTHUMG00000152471 +375484 SIMC1 HGNC:HGNC:24779|Ensembl:ENSG00000170085|Vega:OTTHUMG00000130663 +375513 GUSBP4 HGNC:HGNC:18220 +375519 GJB7 MIM:611921|HGNC:HGNC:16690|Ensembl:ENSG00000164411|Vega:OTTHUMG00000015166 +375567 VWC2 MIM:611108|HGNC:HGNC:30200|Ensembl:ENSG00000188730|Vega:OTTHUMG00000129265 +375593 TRIM73 MIM:612549|HGNC:HGNC:18162|Ensembl:ENSG00000178809|Vega:OTTHUMG00000156075 +375601 OR7E31P HGNC:HGNC:8404 +375607 NAT16 MIM:615783|HGNC:HGNC:22030|Ensembl:ENSG00000167011|Vega:OTTHUMG00000157110 +375611 SLC26A5 MIM:604943|HGNC:HGNC:9359|Ensembl:ENSG00000170615|Vega:OTTHUMG00000149911 +375612 LHFPL3 MIM:609719|HGNC:HGNC:6589|Ensembl:ENSG00000187416|Vega:OTTHUMG00000157273 +375616 KCP MIM:609344|HGNC:HGNC:17585|Ensembl:ENSG00000135253|Vega:OTTHUMG00000158363 +375686 SPATC1 MIM:610874|HGNC:HGNC:30510|Ensembl:ENSG00000186583|Vega:OTTHUMG00000156976 +375690 WASH5P HGNC:HGNC:33884|Ensembl:ENSG00000282458 +375704 ENHO HGNC:HGNC:24838|Ensembl:ENSG00000168913|Vega:OTTHUMG00000159589 +375719 AQP7P1 HGNC:HGNC:32048 +375743 PTAR1 HGNC:HGNC:30449|Ensembl:ENSG00000188647|Vega:OTTHUMG00000019982 +375748 ERCC6L2 MIM:615667|HGNC:HGNC:26922|Ensembl:ENSG00000182150|Vega:OTTHUMG00000020289 +375757 SWI5 MIM:616528|HGNC:HGNC:31412|Ensembl:ENSG00000175854|Vega:OTTHUMG00000020729 +375759 C9orf50 HGNC:HGNC:23677|Ensembl:ENSG00000179058|Vega:OTTHUMG00000020786 +375775 PNPLA7 MIM:612122|HGNC:HGNC:24768|Ensembl:ENSG00000130653|Vega:OTTHUMG00000020990 +375790 AGRN MIM:103320|HGNC:HGNC:329|Ensembl:ENSG00000188157|Vega:OTTHUMG00000040778 +375791 CYSRT1 HGNC:HGNC:30529|Ensembl:ENSG00000197191|Vega:OTTHUMG00000153383 +375850 RBMY2BP HGNC:HGNC:9918 +375940 DMBT1P1 HGNC:HGNC:49497|Ensembl:ENSG00000176584 +376132 LRRC10 MIM:610846|HGNC:HGNC:20264|Ensembl:ENSG00000198812|Vega:OTTHUMG00000169384 +376267 RAB15 HGNC:HGNC:20150|Ensembl:ENSG00000139998|Vega:OTTHUMG00000142810 +376412 RNF126P1 HGNC:HGNC:30340|Ensembl:ENSG00000261192 +376497 SLC27A1 MIM:600691|HGNC:HGNC:10995|Ensembl:ENSG00000130304|Vega:OTTHUMG00000182878 +376693 RPS10P7 HGNC:HGNC:36423 +376818 E2F6P2 HGNC:HGNC:51450 +376844 SDC4P HGNC:HGNC:18903 +376940 ZC3H6 HGNC:HGNC:24762|Ensembl:ENSG00000188177|Vega:OTTHUMG00000153286 +377007 KLHL30 HGNC:HGNC:24770|Ensembl:ENSG00000168427|Vega:OTTHUMG00000152905 +377047 PRSS45 HGNC:HGNC:30717|Ensembl:ENSG00000188086|Vega:OTTHUMG00000133480 +377381 RPL24P4 HGNC:HGNC:21371 +377630 USP17L2 MIM:610186|HGNC:HGNC:34434|Ensembl:ENSG00000223443|Vega:OTTHUMG00000165295 +377677 CA13 MIM:611436|HGNC:HGNC:14914|Ensembl:ENSG00000185015|Vega:OTTHUMG00000164940 +377841 ENTPD8 MIM:616748|HGNC:HGNC:24860|Ensembl:ENSG00000188833|Vega:OTTHUMG00000131831 +377997 TSPY12P HGNC:HGNC:23904 +378001 TSPY13P HGNC:HGNC:23905 +378008 CDY5P HGNC:HGNC:23850 +378009 OFD1P1Y HGNC:HGNC:23873 +378010 OFD1P2Y HGNC:HGNC:23874 +378011 CDY9P HGNC:HGNC:23851 +378013 TSPY14P HGNC:HGNC:23906 +378014 CDY11P HGNC:HGNC:23852 +378108 TRIM74 MIM:612550|HGNC:HGNC:17453|Ensembl:ENSG00000155428|Ensembl:ENSG00000174353|Vega:OTTHUMG00000129851 +378426 AIS2 MIM:608391|HGNC:HGNC:23054 +378427 AIS3 MIM:608392|HGNC:HGNC:23083 +378483 MRX80 HGNC:HGNC:18872 +378484 MRX82 MIM:300518|HGNC:HGNC:21626 +378706 RN7SL2 MIM:612179|HGNC:HGNC:23134|Ensembl:ENSG00000274012 +378707 RN7SL3 MIM:612180|HGNC:HGNC:23135 +378708 CENPS MIM:609130|HGNC:HGNC:23163|Ensembl:ENSG00000175279|Vega:OTTHUMG00000059085 +378805 LINC-PINT HGNC:HGNC:26885|Ensembl:ENSG00000231721 +378807 CATSPER4 MIM:609121|HGNC:HGNC:23220|Ensembl:ENSG00000188782|Vega:OTTHUMG00000003383 +378810 SNX19P1 HGNC:HGNC:16765 +378818 RPL37P3 HGNC:HGNC:17238 +378819 RPL37P4 HGNC:HGNC:17239 +378825 PICSAR MIM:617191|HGNC:HGNC:19725|Ensembl:ENSG00000275874 +378828 LINC00317 HGNC:HGNC:23126|Ensembl:ENSG00000238265 +378832 COL18A1-AS1 HGNC:HGNC:23132|Ensembl:ENSG00000183535 +378881 MIR381HG HGNC:HGNC:20136|Ensembl:ENSG00000258861 +378882 MRX84 MIM:300505|HGNC:HGNC:20228 +378884 NHLRC1 MIM:608072|HGNC:HGNC:21576|Ensembl:ENSG00000187566|Vega:OTTHUMG00000014315 +378888 HSN1B MIM:608088 +378925 RNF148 HGNC:HGNC:22411|Ensembl:ENSG00000235631|Vega:OTTHUMG00000157099 +378938 MALAT1 MIM:607924|HGNC:HGNC:29665 +378948 RBMY1B HGNC:HGNC:23914|Ensembl:ENSG00000242875|Vega:OTTHUMG00000042045 +378949 RBMY1D HGNC:HGNC:23915|Ensembl:ENSG00000244395|Vega:OTTHUMG00000043598 +378950 RBMY1E HGNC:HGNC:23916|Ensembl:ENSG00000242389|Vega:OTTHUMG00000043602 +378951 RBMY1J HGNC:HGNC:23917|Ensembl:ENSG00000226941|Vega:OTTHUMG00000043594 +378952 RBMY2GP HGNC:HGNC:23892 +378953 RBMY2HP HGNC:HGNC:23893 +378955 RBMY2JP HGNC:HGNC:23918 +378956 RBMY2NP HGNC:HGNC:23919 +379003 DFNB40 MIM:608264|HGNC:HGNC:20408 +379005 RBMY2OP HGNC:HGNC:23894 +379006 RBMY2QP HGNC:HGNC:23895 +379007 RBMY2SP HGNC:HGNC:23896 +379008 RBMY2TP HGNC:HGNC:23897 +379009 RBMY2UP HGNC:HGNC:23898 +379010 RBMY2VP HGNC:HGNC:23899 +379011 RBMY2WP HGNC:HGNC:23900 +379012 RBMY2XP HGNC:HGNC:23901 +379013 RNF138P1 HGNC:HGNC:30342 +379024 RBMY2YP HGNC:HGNC:23902 +379025 PSMA3-AS1 HGNC:HGNC:26445|Ensembl:ENSG00000257621 +379027 TSPY5P HGNC:HGNC:23907 +379028 XKRYP1 HGNC:HGNC:23908 +379029 XKRYP2 HGNC:HGNC:23909 +379030 XKRYP3 HGNC:HGNC:23910 +379031 XKRYP4 HGNC:HGNC:23911 +379032 XKRYP5 HGNC:HGNC:23912 +379033 XKRYP6 HGNC:HGNC:23913 +379034 LINC01181 HGNC:HGNC:25533 +386593 CHKB-CPT1B HGNC:HGNC:41998|Ensembl:ENSG00000254413 +386597 RNF144A-AS1 HGNC:HGNC:30963|Ensembl:ENSG00000228203 +386607 ZFP91-CNTF HGNC:HGNC:33441 +386608 RNASEH2CP1 HGNC:HGNC:24117 +386610 E2F6P1 HGNC:HGNC:51449 +386616 SCKL3 HGNC:HGNC:20806 +386617 KCTD8 HGNC:HGNC:22394|Ensembl:ENSG00000183783|Vega:OTTHUMG00000099409 +386618 KCTD4 HGNC:HGNC:23227|Ensembl:ENSG00000180332|Vega:OTTHUMG00000016844 +386627 SAP30L-AS1 HGNC:HGNC:26760 +386653 IL31 MIM:609509|HGNC:HGNC:19372|Ensembl:ENSG00000204671|Vega:OTTHUMG00000168916 +386654 OSTF1P1 HGNC:HGNC:31439 +386665 AURKAPS2 HGNC:HGNC:18612 +386672 KRTAP10-4 HGNC:HGNC:20521|Ensembl:ENSG00000215454|Vega:OTTHUMG00000057641 +386674 KRTAP10-6 HGNC:HGNC:20523|Ensembl:ENSG00000188155|Vega:OTTHUMG00000057634 +386675 KRTAP10-7 HGNC:HGNC:22970|Ensembl:ENSG00000272804|Vega:OTTHUMG00000188307 +386676 KRTAP10-9 HGNC:HGNC:22971|Ensembl:ENSG00000221837|Vega:OTTHUMG00000057637 +386677 KRTAP10-1 HGNC:HGNC:22966|Ensembl:ENSG00000215455|Vega:OTTHUMG00000057627 +386678 KRTAP10-11 HGNC:HGNC:20528|Ensembl:ENSG00000243489|Vega:OTTHUMG00000057626 +386679 KRTAP10-2 HGNC:HGNC:22967|Ensembl:ENSG00000205445|Vega:OTTHUMG00000057625 +386680 KRTAP10-5 HGNC:HGNC:22969|Ensembl:ENSG00000241123|Vega:OTTHUMG00000057638 +386681 KRTAP10-8 HGNC:HGNC:20525|Ensembl:ENSG00000187766|Vega:OTTHUMG00000057632 +386682 KRTAP10-3 HGNC:HGNC:22968|Ensembl:ENSG00000212935|Vega:OTTHUMG00000057628 +386683 KRTAP12-3 HGNC:HGNC:20531|Ensembl:ENSG00000205439|Vega:OTTHUMG00000057630 +386684 KRTAP12-4 HGNC:HGNC:20532|Ensembl:ENSG00000212933|Vega:OTTHUMG00000057633 +386685 KRTAP10-12 HGNC:HGNC:20533|Ensembl:ENSG00000189169|Vega:OTTHUMG00000057629 +386687 OFD1P3Y HGNC:HGNC:23875 +386688 OFD1P4Y HGNC:HGNC:23876 +386689 OFD1P5Y HGNC:HGNC:23877 +386690 OFD1P6Y HGNC:HGNC:13657 +386691 OFD1P7Y HGNC:HGNC:23879 +386692 OFD1P8Y HGNC:HGNC:23880 +386693 OFD1P9Y HGNC:HGNC:23881 +386694 OFD1P10Y HGNC:HGNC:23882 +386695 OFD1P11Y HGNC:HGNC:23883 +386696 OFD1P12Y HGNC:HGNC:23884 +386697 OFD1P13Y HGNC:HGNC:23885 +386698 OFD1P14Y HGNC:HGNC:23886 +386699 OFD1P15Y HGNC:HGNC:23887 +386724 AMIGO3 MIM:615691|HGNC:HGNC:24075|Ensembl:ENSG00000176020|Vega:OTTHUMG00000158152 +386725 FAM8A7P HGNC:HGNC:23868 +386726 FAM8A4P HGNC:HGNC:16375 +386727 FAM8A9P HGNC:HGNC:23870 +386728 FAM8A10P HGNC:HGNC:23871 +386729 CDY4P HGNC:HGNC:23872 +386730 CDY6P HGNC:HGNC:23853 +386731 CDY7P HGNC:HGNC:23854 +386732 CDY8P HGNC:HGNC:23855 +386734 CDY12P HGNC:HGNC:23856 +386735 CDY13P HGNC:HGNC:23857 +386736 CDY14P HGNC:HGNC:23858 +386737 CDY15P HGNC:HGNC:23859 +386738 CDY16P HGNC:HGNC:23860 +386739 CDY17P HGNC:HGNC:23861 +386740 CDY18P HGNC:HGNC:23862 +386741 CDY19P HGNC:HGNC:23863 +386742 CDY20P HGNC:HGNC:23864 +386743 CDY21P HGNC:HGNC:23865 +386744 CDY22P HGNC:HGNC:23866 +386745 CDY23P HGNC:HGNC:23867 +386746 MRGPRG MIM:607234|HGNC:HGNC:24829|Ensembl:ENSG00000182170|Vega:OTTHUMG00000011709 +386757 SLC6A10P HGNC:HGNC:11043|Ensembl:ENSG00000214617 +386758 ZNF582-AS1 HGNC:HGNC:25213|Ensembl:ENSG00000267454 +387032 ZKSCAN4 MIM:611643|HGNC:HGNC:13854|Ensembl:ENSG00000187626|Vega:OTTHUMG00000014511 +387036 GUSBP2 HGNC:HGNC:18792|Ensembl:ENSG00000241549 +387039 HTATSF1P1 HGNC:HGNC:13959 +387043 RPL13AP HGNC:HGNC:13977 +387044 RPL13P HGNC:HGNC:13978 +387046 RPL8P1 HGNC:HGNC:13980 +387055 LINC00533 HGNC:HGNC:18690|Ensembl:ENSG00000235570 +387063 HMGA1P5 HGNC:HGNC:19120 +387065 HMGA1P7 HGNC:HGNC:19122 +387066 SNHG5 MIM:613263|HGNC:HGNC:21026|Ensembl:ENSG00000203875 +387071 FAM136BP HGNC:HGNC:21110 +387074 RPL35AP3 HGNC:HGNC:21117 +387082 SUMO4 MIM:608829|HGNC:HGNC:21181|Ensembl:ENSG00000177688|Vega:OTTHUMG00000015785 +387090 RPL36AP5 HGNC:HGNC:21258 +387101 RPL29P4 HGNC:HGNC:21482 +387103 CENPW MIM:611264|HGNC:HGNC:21488|Ensembl:ENSG00000203760|Vega:OTTHUMG00000015518 +387104 SOGA3 HGNC:HGNC:21494|Ensembl:ENSG00000214338|Ensembl:ENSG00000255330|Vega:OTTHUMG00000015528|Vega:OTTHUMG00000166438 +387107 ATP5J2P2 HGNC:HGNC:21540 +387111 LINC00222 HGNC:HGNC:21560|Ensembl:ENSG00000203801 +387117 UBQLN1P1 HGNC:HGNC:21633 +387119 CEP85L HGNC:HGNC:21638|Ensembl:ENSG00000111860|Vega:OTTHUMG00000015465 +387122 WASF5P HGNC:HGNC:21665 +387129 NPSR1 MIM:608595|HGNC:HGNC:23631|Ensembl:ENSG00000187258|Vega:OTTHUMG00000099383 +387254 SLC7A5P2 HGNC:HGNC:24951 +387263 C6orf120 MIM:616987|HGNC:HGNC:21247|Ensembl:ENSG00000185127|Vega:OTTHUMG00000016057 +387264 KRTAP5-1 MIM:148022|HGNC:HGNC:23596|Ensembl:ENSG00000205869|Vega:OTTHUMG00000057557 +387266 KRTAP5-3 HGNC:HGNC:23598|Ensembl:ENSG00000196224|Vega:OTTHUMG00000057559 +387267 KRTAP5-4 HGNC:HGNC:23599 +387273 KRTAP5-10 HGNC:HGNC:23605|Ensembl:ENSG00000204572|Vega:OTTHUMG00000057585 +387275 KRTAP5-13P HGNC:HGNC:23607 +387276 KRTAP5-14P HGNC:HGNC:23608 +387315 MTND2P1 HGNC:HGNC:7457 +387316 VN1R10P HGNC:HGNC:13550 +387317 VN1R11P HGNC:HGNC:13551 +387319 HIST1H2APS1 HGNC:HGNC:18720 +387320 VN1R14P HGNC:HGNC:18721 +387321 VN1R12P HGNC:HGNC:18722 +387322 VN1R13P HGNC:HGNC:18723 +387323 HIST1H2APS3 HGNC:HGNC:18805 +387325 HIST1H1PS1 HGNC:HGNC:19163 +387328 ZNF322P1 HGNC:HGNC:14003 +387332 TBPL2 MIM:608964|HGNC:HGNC:19841|Ensembl:ENSG00000182521|Vega:OTTHUMG00000140313 +387338 NSUN4 MIM:615394|HGNC:HGNC:31802|Ensembl:ENSG00000117481|Vega:OTTHUMG00000007808 +387357 THEMIS MIM:613607|HGNC:HGNC:21569|Ensembl:ENSG00000172673|Vega:OTTHUMG00000015534 +387359 USP9YP4 HGNC:HGNC:37740 +387361 USP9YP34 HGNC:HGNC:38778 +387362 USP9YP1 HGNC:HGNC:31741 +387363 USP9YP2 HGNC:HGNC:31742 +387364 USP9YP3 HGNC:HGNC:37739 +387486 LINC00320 HGNC:HGNC:19690|Ensembl:ENSG00000224924 +387491 GAPDHP16 HGNC:HGNC:23768 +387492 DSTNP1 HGNC:HGNC:23769 +387494 RPL18AP2 HGNC:HGNC:23774 +387495 RPS26P5 HGNC:HGNC:23776 +387496 RASL11A MIM:612403|HGNC:HGNC:23802|Ensembl:ENSG00000122035|Vega:OTTHUMG00000016627 +387503 HCG4P1 HGNC:HGNC:30978 +387504 HCG4P2 HGNC:HGNC:30979 +387505 HCG9P1 HGNC:HGNC:30980 +387506 HCG9P2 HGNC:HGNC:30981 +387507 HCG9P3 HGNC:HGNC:30982 +387509 GPR153 MIM:614269|HGNC:HGNC:23618|Ensembl:ENSG00000158292|Vega:OTTHUMG00000001272 +387521 TMEM189 MIM:610994|HGNC:HGNC:16735|Ensembl:ENSG00000240849|Vega:OTTHUMG00000152625 +387522 TMEM189-UBE2V1 HGNC:HGNC:33521|Ensembl:ENSG00000124208|Vega:OTTHUMG00000033085 +387553 DNM1P18 HGNC:HGNC:21135 +387554 DNM1P19 HGNC:HGNC:21136 +387559 FGF7P1 HGNC:HGNC:21455 +387569 ACF MIM:125520 +387570 DUH1 MIM:127500 +387572 PAND1 MIM:167870 +387573 CHDS3 MIM:300464 +387574 CMTDIA MIM:606483 +387575 HYT3 MIM:607329 +387576 MGR5 MIM:607508 +387577 AUTS3 MIM:608049 +387578 AITD1 MIM:608173 +387579 AITD2 MIM:608174 +387581 AITD4 MIM:608176 +387582 KAZA1 MIM:608207 +387583 SPG25 MIM:608220|HGNC:HGNC:25855 +387584 CHDS2 MIM:608316 +387585 CHDS4 MIM:608318 +387590 TPTEP1 HGNC:HGNC:43648|Ensembl:ENSG00000100181 +387597 ILDR2 HGNC:HGNC:18131|Ensembl:ENSG00000143195|Vega:OTTHUMG00000034320 +387601 SLC22A25 MIM:610792|HGNC:HGNC:32935|Ensembl:ENSG00000196600|Vega:OTTHUMG00000165340 +387612 RAC1P1 HGNC:HGNC:31001 +387615 MAP1LC3P HGNC:HGNC:31004 +387628 FGF7P6 HGNC:HGNC:27852|Ensembl:ENSG00000227449 +387638 C10orf113 HGNC:HGNC:31447|Ensembl:ENSG00000204683|Vega:OTTHUMG00000017786 +387640 SKIDA1 HGNC:HGNC:32697|Ensembl:ENSG00000180592|Vega:OTTHUMG00000017797 +387644 FAM238C HGNC:HGNC:24672|Ensembl:ENSG00000283709 +387646 LRRC37A6P HGNC:HGNC:33746|Ensembl:ENSG00000230445 +387647 PTCHD3P1 HGNC:HGNC:44945 +387680 WASHC2A HGNC:HGNC:23416|Ensembl:ENSG00000099290|Vega:OTTHUMG00000018225 +387684 ARL4AP1 HGNC:HGNC:17741 +387694 SH2D4B HGNC:HGNC:31440|Ensembl:ENSG00000178217|Vega:OTTHUMG00000018617 +387695 C10orf99 HGNC:HGNC:31428|Ensembl:ENSG00000188373|Vega:OTTHUMG00000018635 +387700 SLC16A12 MIM:611910|HGNC:HGNC:23094|Ensembl:ENSG00000152779|Vega:OTTHUMG00000018714 +387703 XRCC6P1 HGNC:HGNC:45183 +387707 CC2D2B HGNC:HGNC:31666|Ensembl:ENSG00000188649|Vega:OTTHUMG00000191767 +387712 ENO4 MIM:131375|HGNC:HGNC:31670|Ensembl:ENSG00000188316 +387715 ARMS2 MIM:611313|HGNC:HGNC:32685|Ensembl:ENSG00000254636|Vega:OTTHUMG00000048232 +387718 TEX36 HGNC:HGNC:31653|Ensembl:ENSG00000175018|Vega:OTTHUMG00000019229 +387723 LINC00959 HGNC:HGNC:48677 +387733 IFITM5 MIM:614757|HGNC:HGNC:16644|Ensembl:ENSG00000206013|Vega:OTTHUMG00000165355 +387742 FAM99A HGNC:HGNC:32368|Ensembl:ENSG00000205866 +387745 FAM86GP HGNC:HGNC:42358 +387747 OR52B3P HGNC:HGNC:15208 +387748 OR56B1 HGNC:HGNC:15245|Ensembl:ENSG00000181023|Vega:OTTHUMG00000066891 +387751 GVINP1 MIM:616121|HGNC:HGNC:25813|Ensembl:ENSG00000254838 +387753 RPL21P97 HGNC:HGNC:36223 +387755 INSC MIM:610668|HGNC:HGNC:33116|Ensembl:ENSG00000188487|Vega:OTTHUMG00000165838 +387758 FIBIN MIM:617085|HGNC:HGNC:33747|Ensembl:ENSG00000176971|Vega:OTTHUMG00000166120 +387763 C11orf96 HGNC:HGNC:38675|Ensembl:ENSG00000187479|Vega:OTTHUMG00000166555 +387770 LOC387770 - +387775 SLC22A10 MIM:607580|HGNC:HGNC:18057|Ensembl:ENSG00000184999|Vega:OTTHUMG00000165197 +387778 SPDYC MIM:614030|HGNC:HGNC:32681|Ensembl:ENSG00000204710|Vega:OTTHUMG00000165611 +387787 LIPT2 HGNC:HGNC:37216|Ensembl:ENSG00000175536|Vega:OTTHUMG00000165646 +387804 VSTM5 HGNC:HGNC:34443|Ensembl:ENSG00000214376|Vega:OTTHUMG00000154159 +387810 LOC387810 Ensembl:ENSG00000255484 +387815 OR8G3P HGNC:HGNC:14698 +387820 LOC387820 - +387836 CLEC2A MIM:612087|HGNC:HGNC:24191|Ensembl:ENSG00000188393|Vega:OTTHUMG00000140393 +387837 CLEC12B MIM:617573|HGNC:HGNC:31966|Ensembl:ENSG00000256660|Vega:OTTHUMG00000168397 +387841 RPL13AP20 HGNC:HGNC:35709|Ensembl:ENSG00000234498 +387845 EEF1A1P16 HGNC:HGNC:37889 +387849 REP15 MIM:610848|HGNC:HGNC:33748|Ensembl:ENSG00000174236|Vega:OTTHUMG00000169212 +387853 OR7A19P HGNC:HGNC:15337 +387856 CCDC184 HGNC:HGNC:33749|Ensembl:ENSG00000177875|Vega:OTTHUMG00000169902 +387867 RPSAP12 HGNC:HGNC:6504 +387869 LOC387869 - +387882 C12orf75 HGNC:HGNC:35164|Ensembl:ENSG00000235162|Vega:OTTHUMG00000150129 +387885 CFAP73 HGNC:HGNC:37100|Ensembl:ENSG00000186710|Vega:OTTHUMG00000169655 +387890 TMEM233 HGNC:HGNC:37219|Ensembl:ENSG00000224982|Vega:OTTHUMG00000168944 +387893 KMT5A MIM:607240|HGNC:HGNC:29489|Ensembl:ENSG00000183955|Vega:OTTHUMG00000150477 +387895 LINC00944 HGNC:HGNC:48640 +387911 C1QTNF9B MIM:614148|HGNC:HGNC:34072|Ensembl:ENSG00000205863|Vega:OTTHUMG00000016570 +387914 SHISA2 MIM:617324|HGNC:HGNC:20366|Ensembl:ENSG00000180730|Vega:OTTHUMG00000016612 +387921 NHLRC3 HGNC:HGNC:33751|Ensembl:ENSG00000188811|Vega:OTTHUMG00000016765 +387923 SERP2 HGNC:HGNC:20607|Ensembl:ENSG00000151778|Vega:OTTHUMG00000016833 +387924 OGFOD1P1 HGNC:HGNC:39202 +387933 HNRNPA3P5 HGNC:HGNC:39774 +387934 FABP5P1 HGNC:HGNC:31059 +387978 LINC01551 HGNC:HGNC:19828|Ensembl:ENSG00000186960 +387990 TOMM20L HGNC:HGNC:33752|Ensembl:ENSG00000196860|Vega:OTTHUMG00000140323 +388007 SERPINA13P HGNC:HGNC:30909|Ensembl:ENSG00000187483 +388011 LINC01550 HGNC:HGNC:20111|Ensembl:ENSG00000246223 +388015 RTL1 MIM:611896|HGNC:HGNC:14665|Ensembl:ENSG00000254656|Vega:OTTHUMG00000167573 +388021 TMEM179 HGNC:HGNC:20137|Ensembl:ENSG00000258986|Vega:OTTHUMG00000170829 +388022 LOC388022 - +388076 RPS8P10 HGNC:HGNC:35628 +388077 IGHV1OR15-1 HGNC:HGNC:5563|IMGT/GENE-DB:IGHV1/OR15-1 +388104 LOC388104 - +388112 NANOGP8 HGNC:HGNC:23106 +388115 C15orf52 HGNC:HGNC:33488|Ensembl:ENSG00000188549|Vega:OTTHUMG00000129981 +388121 TNFAIP8L3 MIM:616438|HGNC:HGNC:20620|Ensembl:ENSG00000183578|Vega:OTTHUMG00000172460 +388122 RPSAP55 HGNC:HGNC:36921 +388125 C2CD4B MIM:610344|HGNC:HGNC:33628|Ensembl:ENSG00000205502|Vega:OTTHUMG00000171959 +388132 RPL17P5 HGNC:HGNC:35491 +388135 C15orf59 MIM:617128|HGNC:HGNC:33753|Ensembl:ENSG00000205363|Vega:OTTHUMG00000172556 +388152 GOLGA2P7 HGNC:HGNC:49516|Ensembl:ENSG00000225151 +388165 UBE2Q2P1 HGNC:HGNC:37439|Ensembl:ENSG00000189136 +388181 FAM149B1P1 HGNC:HGNC:31735 +388182 SPATA41 HGNC:HGNC:48613|Ensembl:ENSG00000189419 +388199 PRR25 HGNC:HGNC:37230|Ensembl:ENSG00000167945|Vega:OTTHUMG00000178117 +388228 SBK1 HGNC:HGNC:17699|Ensembl:ENSG00000188322|Vega:OTTHUMG00000166066 +388242 LOC388242 Ensembl:ENSG00000258150|Vega:OTTHUMG00000170469 +388248 LOC388248 - +388254 HERC2P5 HGNC:HGNC:4873 +388255 IGHV3OR16-8 HGNC:HGNC:5643|IMGT/GENE-DB:IGHV3/OR16-8 +388272 C16orf87 HGNC:HGNC:33754|Ensembl:ENSG00000155330|Vega:OTTHUMG00000132538 +388275 HNRNPA1P7 HGNC:HGNC:31015 +388276 C16orf97 HGNC:HGNC:44658 +388282 LOC388282 - +388284 C16orf86 HGNC:HGNC:33755|Ensembl:ENSG00000159761|Vega:OTTHUMG00000150527 +388289 C16orf47 HGNC:HGNC:28329 +388323 GLTPD2 HGNC:HGNC:33756|Ensembl:ENSG00000182327|Vega:OTTHUMG00000177929 +388324 INCA1 MIM:617374|HGNC:HGNC:32224|Ensembl:ENSG00000196388|Vega:OTTHUMG00000177768 +388325 SCIMP MIM:614406|HGNC:HGNC:33504|Ensembl:ENSG00000161929|Vega:OTTHUMG00000132914 +388327 C17orf100 HGNC:HGNC:34494|Ensembl:ENSG00000256806 +388333 SPDYE4 HGNC:HGNC:35463|Ensembl:ENSG00000183318|Vega:OTTHUMG00000178566 +388335 TMEM220 HGNC:HGNC:33757|Ensembl:ENSG00000187824|Vega:OTTHUMG00000178043 +388336 SHISA6 MIM:617327|HGNC:HGNC:34491|Ensembl:ENSG00000188803|Vega:OTTHUMG00000154121 +388339 RPS18P12 HGNC:HGNC:35967 +388341 LRRC75A HGNC:HGNC:32403|Ensembl:ENSG00000181350|Vega:OTTHUMG00000058988 +388344 RPL13P12 HGNC:HGNC:35701 +388363 RPS7P1 HGNC:HGNC:17081 +388364 TMIGD1 HGNC:HGNC:32431|Ensembl:ENSG00000182271|Vega:OTTHUMG00000179757 +388372 CCL4L1 MIM:603782|HGNC:HGNC:10631 +388381 C17orf98 HGNC:HGNC:34492|Ensembl:ENSG00000275489|Vega:OTTHUMG00000188506 +388387 LINC00671 HGNC:HGNC:44339|Ensembl:ENSG00000213373 +388389 CCDC103 MIM:614677|HGNC:HGNC:32700|Ensembl:ENSG00000167131|Ensembl:ENSG00000214447|Vega:OTTHUMG00000154264 +388394 RPRML HGNC:HGNC:32422|Ensembl:ENSG00000179673|Vega:OTTHUMG00000178187 +388401 RPL7P48 HGNC:HGNC:35540 +388403 YPEL2 MIM:609723|HGNC:HGNC:18326|Ensembl:ENSG00000175155|Vega:OTTHUMG00000179378 +388406 LINC01999 HGNC:HGNC:52834|Ensembl:ENSG00000267772 +388407 C17orf82 HGNC:HGNC:32699 +388419 BTBD17 HGNC:HGNC:33758|Ensembl:ENSG00000204347|Vega:OTTHUMG00000178580 +388428 PVALEF HGNC:HGNC:40053|Ensembl:ENSG00000225180|Vega:OTTHUMG00000150182 +388436 LOC388436 - +388456 LINC01904 HGNC:HGNC:52723|Ensembl:ENSG00000259837 +388460 RPL6P22 HGNC:HGNC:36220 +388468 POTEC HGNC:HGNC:33894|Ensembl:ENSG00000183206|Vega:OTTHUMG00000162963 +388474 RPL7AP66 HGNC:HGNC:35682 +388478 SDCCAG3P1 HGNC:HGNC:29375 +388499 LYPLA2P2 HGNC:HGNC:50445 +388503 C3P1 HGNC:HGNC:34414|Ensembl:ENSG00000167798 +388507 ZNF788 HGNC:HGNC:33112|Ensembl:ENSG00000214189|Vega:OTTHUMG00000156416 +388512 CLEC17A MIM:616838|HGNC:HGNC:34520|Ensembl:ENSG00000187912|Vega:OTTHUMG00000169312 +388514 CYP4F24P HGNC:HGNC:39945 +388523 ZNF728 HGNC:HGNC:32463|Ensembl:ENSG00000269067|Vega:OTTHUMG00000183124 +388524 RPSAP58 HGNC:HGNC:36809 +388531 RGS9BP MIM:607814|HGNC:HGNC:30304|Ensembl:ENSG00000186326|Vega:OTTHUMG00000180227 +388532 RPL21P131 HGNC:HGNC:36428 +388533 KRTDAP MIM:617212|HGNC:HGNC:16313|Ensembl:ENSG00000188508|Vega:OTTHUMG00000155449 +388536 ZNF790 HGNC:HGNC:33114|Ensembl:ENSG00000197863|Vega:OTTHUMG00000165616 +388550 CEACAM22P HGNC:HGNC:38029|Ensembl:ENSG00000230666 +388551 CEACAM16 MIM:614591|HGNC:HGNC:31948|Ensembl:ENSG00000213892|Vega:OTTHUMG00000151519 +388552 BLOC1S3 MIM:609762|HGNC:HGNC:20914|Ensembl:ENSG00000189114|Vega:OTTHUMG00000181776 +388553 BHMG1 HGNC:HGNC:44318|Ensembl:ENSG00000237452|Vega:OTTHUMG00000156178 +388555 IGFL3 MIM:610546|HGNC:HGNC:32930|Ensembl:ENSG00000188624|Vega:OTTHUMG00000172904 +388556 RPS9P4 HGNC:HGNC:36710 +388558 ZNF808 HGNC:HGNC:33230|Ensembl:ENSG00000198482|Vega:OTTHUMG00000158230 +388559 ZNF888 HGNC:HGNC:38695|Ensembl:ENSG00000213793 +388560 ERVFRD-2 HGNC:HGNC:35201 +388561 ZNF761 HGNC:HGNC:23179|Ensembl:ENSG00000160336|Vega:OTTHUMG00000156999 +388564 TMEM238 HGNC:HGNC:40042|Ensembl:ENSG00000233493|Vega:OTTHUMG00000180795 +388566 ZNF470 HGNC:HGNC:22220|Ensembl:ENSG00000197016|Vega:OTTHUMG00000182141 +388567 ZNF749 HGNC:HGNC:32783|Ensembl:ENSG00000186230|Vega:OTTHUMG00000150372 +388569 ZNF324B HGNC:HGNC:33107|Ensembl:ENSG00000249471|Vega:OTTHUMG00000183539 +388572 LOC388572 - +388574 RPL23AP87 HGNC:HGNC:51578|Ensembl:ENSG00000232938 +388579 TUBB8P11 HGNC:HGNC:32337 +388581 C1QTNF12 MIM:616593|HGNC:HGNC:32308|Ensembl:ENSG00000184163|Vega:OTTHUMG00000001412 +388585 HES5 MIM:607348|HGNC:HGNC:19764|Ensembl:ENSG00000197921|Vega:OTTHUMG00000000793 +388588 SMIM1 MIM:615242|HGNC:HGNC:44204|Ensembl:ENSG00000235169|Vega:OTTHUMG00000003505 +388591 RNF207 MIM:616923|HGNC:HGNC:32947|Ensembl:ENSG00000158286|Vega:OTTHUMG00000001089 +388595 TMEM82 HGNC:HGNC:32350|Ensembl:ENSG00000162460|Vega:OTTHUMG00000003065 +388605 HS6ST1P1 HGNC:HGNC:31835 +388606 SDHDP7 HGNC:HGNC:31410 +388610 TRNP1 MIM:616824|HGNC:HGNC:34348|Ensembl:ENSG00000253368|Vega:OTTHUMG00000004277 +388611 CD164L2 HGNC:HGNC:32043|Ensembl:ENSG00000174950|Vega:OTTHUMG00000003395 +388621 RPL21P20 HGNC:HGNC:36582 +388630 TRABD2B MIM:614913|HGNC:HGNC:44200|Ensembl:ENSG00000269113|Vega:OTTHUMG00000007960 +388633 LDLRAD1 HGNC:HGNC:32069|Ensembl:ENSG00000203985|Vega:OTTHUMG00000008433 +388646 GBP7 MIM:612468|HGNC:HGNC:29606|Ensembl:ENSG00000213512|Vega:OTTHUMG00000010659 +388649 C1orf146 HGNC:HGNC:24032|Ensembl:ENSG00000203910|Vega:OTTHUMG00000010285 +388650 FAM69A MIM:614542|HGNC:HGNC:32213|Ensembl:ENSG00000154511|Vega:OTTHUMG00000010894 +388662 SLC6A17 MIM:610299|HGNC:HGNC:31399|Ensembl:ENSG00000197106|Vega:OTTHUMG00000011761 +388667 C1orf137 HGNC:HGNC:32040 +388677 NOTCH2NL HGNC:HGNC:31862|Ensembl:ENSG00000264343|Vega:OTTHUMG00000013754 +388685 LINC01138 HGNC:HGNC:49454|Ensembl:ENSG00000274020 +388692 LOC388692 - +388695 LYSMD1 HGNC:HGNC:32070|Ensembl:ENSG00000163155|Vega:OTTHUMG00000012260 +388697 HRNR MIM:616293|HGNC:HGNC:20846|Ensembl:ENSG00000197915|Vega:OTTHUMG00000012243 +388698 FLG2 MIM:616284|HGNC:HGNC:33276|Ensembl:ENSG00000143520|Vega:OTTHUMG00000012245 +388699 LINC00302 HGNC:HGNC:31825 +388701 C1orf189 HGNC:HGNC:32305|Ensembl:ENSG00000163263|Vega:OTTHUMG00000035982 +388707 RPSAP18 HGNC:HGNC:36106 +388714 FMO6P HGNC:HGNC:24024|Ensembl:ENSG00000117507 +388719 LINC00272 HGNC:HGNC:26898|Ensembl:ENSG00000203729 +388722 C1orf53 HGNC:HGNC:30003|Ensembl:ENSG00000203724|Vega:OTTHUMG00000035659 +388730 TMEM81 HGNC:HGNC:32349|Ensembl:ENSG00000174529|Vega:OTTHUMG00000037103 +388734 LOC388734 - +388743 CAPN8 HGNC:HGNC:1485|Ensembl:ENSG00000203697|Vega:OTTHUMG00000037378 +388753 COA6 MIM:614772|HGNC:HGNC:18025|Ensembl:ENSG00000168275|Vega:OTTHUMG00000037945 +388759 C1orf229 HGNC:HGNC:33759 +388761 OR14A2 HGNC:HGNC:15024 +388762 OR2M1P HGNC:HGNC:8267 +388780 LOC388780 - +388789 SMIM26 HGNC:HGNC:43430|Ensembl:ENSG00000232388|Vega:OTTHUMG00000031978 +388795 EFCAB8 HGNC:HGNC:34532|Ensembl:ENSG00000215529|Vega:OTTHUMG00000153693 +388796 SNHG17 HGNC:HGNC:48600|Ensembl:ENSG00000196756 +388799 FAM209B HGNC:HGNC:16101|Ensembl:ENSG00000213714|Vega:OTTHUMG00000032800 +388813 LOC388813 Ensembl:ENSG00000243440|Vega:OTTHUMG00000074315 +388815 MIR99AHG MIM:615964|HGNC:HGNC:1274 +388818 KRTAP26-1 HGNC:HGNC:33760|Ensembl:ENSG00000197683|Vega:OTTHUMG00000057766 +388820 LOC388820 Ensembl:ENSG00000243627|Vega:OTTHUMG00000153030 +388830 LINC00316 HGNC:HGNC:19723|Ensembl:ENSG00000237664 +388849 CCDC188 HGNC:HGNC:51899|Ensembl:ENSG00000234409|Vega:OTTHUMG00000150751 +388882 LINC01658 HGNC:HGNC:52446|Ensembl:ENSG00000178248 +388885 RPS10P29 HGNC:HGNC:37120 +388886 LRRC75B HGNC:HGNC:33155|Ensembl:ENSG00000178026|Vega:OTTHUMG00000150729 +388906 OGFRP1 HGNC:HGNC:50511|Ensembl:ENSG00000182057 +388907 RPL5P34 HGNC:HGNC:36463 +388910 LINC00207 HGNC:HGNC:37255|Ensembl:ENSG00000187012 +388925 PSMC1P10 HGNC:HGNC:39785 +388931 MFSD2B HGNC:HGNC:37207|Ensembl:ENSG00000205639|Vega:OTTHUMG00000090819 +388939 C2orf71 MIM:613425|HGNC:HGNC:34383|Ensembl:ENSG00000179270|Vega:OTTHUMG00000152024 +388942 LINC01913 HGNC:HGNC:52732|Ensembl:ENSG00000214691 +388946 TMEM247 HGNC:HGNC:42967|Ensembl:ENSG00000187600|Vega:OTTHUMG00000153137 +388948 LINC01118 HGNC:HGNC:49261|Ensembl:ENSG00000222005 +388951 TSPYL6 HGNC:HGNC:14521|Ensembl:ENSG00000178021|Vega:OTTHUMG00000151823 +388955 LOC388955 - +388960 C2orf78 HGNC:HGNC:34349|Ensembl:ENSG00000187833|Vega:OTTHUMG00000152819 +388962 BOLA3 MIM:613183|HGNC:HGNC:24415|Ensembl:ENSG00000163170|Vega:OTTHUMG00000152834 +388963 C2orf81 HGNC:HGNC:34350|Ensembl:ENSG00000284308 +388965 FUNDC2P2 HGNC:HGNC:17247 +388969 C2orf68 HGNC:HGNC:34353|Ensembl:ENSG00000168887|Vega:OTTHUMG00000153088 +388996 LOC388996 - +389000 SLC9B1P2 HGNC:HGNC:37493 +389015 SLC9A4 MIM:600531|HGNC:HGNC:11077|Ensembl:ENSG00000180251|Vega:OTTHUMG00000153093 +389023 DPP10-AS1 HGNC:HGNC:40941|Ensembl:ENSG00000235026 +389033 PLAC9P1 HGNC:HGNC:52678|Ensembl:ENSG00000214100 +389043 LINC01120 HGNC:HGNC:49265 +389053 HNRNPKP2 HGNC:HGNC:42375 +389058 SP5 MIM:609391|HGNC:HGNC:14529|Ensembl:ENSG00000204335|Vega:OTTHUMG00000154053 +389072 PLEKHM3 HGNC:HGNC:34006|Ensembl:ENSG00000178385|Vega:OTTHUMG00000154781 +389073 C2orf80 MIM:615536|HGNC:HGNC:34352|Ensembl:ENSG00000188674|Vega:OTTHUMG00000154751 +389075 RESP18 MIM:612721|HGNC:HGNC:33762|Ensembl:ENSG00000182698|Vega:OTTHUMG00000150223 +389084 C2orf82 HGNC:HGNC:33763|Ensembl:ENSG00000182600|Vega:OTTHUMG00000133273 +389090 OR6B2 HGNC:HGNC:15041|Ensembl:ENSG00000182083|Vega:OTTHUMG00000152400 +389101 RPL23AP43 HGNC:HGNC:35751 +389112 RPS27P4 HGNC:HGNC:16694 +389114 ZNF662 HGNC:HGNC:31930|Ensembl:ENSG00000182983|Vega:OTTHUMG00000133041 +389118 CDHR4 HGNC:HGNC:34527|Ensembl:ENSG00000187492|Vega:OTTHUMG00000158198 +389119 FAM212A HGNC:HGNC:32480|Ensembl:ENSG00000185614|Vega:OTTHUMG00000158268 +389120 ACTBP13 HGNC:HGNC:44626 +389123 IQCF2 HGNC:HGNC:31815|Ensembl:ENSG00000184345|Vega:OTTHUMG00000156914 +389124 IQCF5 HGNC:HGNC:35159|Ensembl:ENSG00000214681|Vega:OTTHUMG00000156913 +389125 MUSTN1 MIM:617195|HGNC:HGNC:22144|Ensembl:ENSG00000272573|Vega:OTTHUMG00000159024 +389127 RPS10P10 HGNC:HGNC:37034 +389136 VGLL3 MIM:609980|HGNC:HGNC:24327|Ensembl:ENSG00000206538|Vega:OTTHUMG00000158984 +389137 ARMC10P1 HGNC:HGNC:43646 +389141 RPSAP29 HGNC:HGNC:36680 +389144 OR7E130P HGNC:HGNC:15053 +389151 PRR23B HGNC:HGNC:33764|Ensembl:ENSG00000184814|Vega:OTTHUMG00000160633 +389152 PRR23C HGNC:HGNC:37173|Ensembl:ENSG00000233701|Vega:OTTHUMG00000160634 +389156 RPL21P39 HGNC:HGNC:36127 +389158 PLSCR5 HGNC:HGNC:19952|Ensembl:ENSG00000231213|Vega:OTTHUMG00000159437 +389160 CPHL1P HGNC:HGNC:31714 +389161 ANKUB1 HGNC:HGNC:29642|Ensembl:ENSG00000206199|Vega:OTTHUMG00000159615 +389168 SETP14 HGNC:HGNC:42933 +389170 LEKR1 MIM:613536|HGNC:HGNC:33765|Ensembl:ENSG00000197980|Vega:OTTHUMG00000160130 +389177 TMEM212 HGNC:HGNC:34295|Ensembl:ENSG00000186329|Vega:OTTHUMG00000156839 +389179 EEF1A1P8 HGNC:HGNC:3203 +389180 5-HT3C2 - +389197 C4orf50 HGNC:HGNC:33766|Ensembl:ENSG00000181215|Vega:OTTHUMG00000149971 +389199 LOC389199 - +389203 SMIM20 MIM:617465|HGNC:HGNC:37260|Ensembl:ENSG00000250317|Vega:OTTHUMG00000160330 +389206 BEND4 HGNC:HGNC:23815|Ensembl:ENSG00000188848|Vega:OTTHUMG00000160531 +389207 GRXCR1 MIM:613283|HGNC:HGNC:31673|Ensembl:ENSG00000215203|Vega:OTTHUMG00000160434 +389208 TMPRSS11F HGNC:HGNC:29994|Ensembl:ENSG00000198092|Vega:OTTHUMG00000129307 +389217 SETP20 HGNC:HGNC:42939 +389223 EEF1A1P35 HGNC:HGNC:37913 +389240 NACA3P HGNC:HGNC:33442 +389246 VTI1BP2 HGNC:HGNC:43728 +389247 LOC389247 - +389249 LOC389249 - +389257 LRRC14B HGNC:HGNC:37268|Ensembl:ENSG00000185028|Vega:OTTHUMG00000161578 +389273 LINC02213 HGNC:HGNC:53080|Ensembl:ENSG00000249160 +389289 ANXA2R MIM:611296|HGNC:HGNC:33463|Ensembl:ENSG00000177721|Vega:OTTHUMG00000162232 +389293 ISCA1P1 HGNC:HGNC:33263 +389320 TEX43 HGNC:HGNC:33767|Ensembl:ENSG00000196900|Vega:OTTHUMG00000128944 +389322 HNRNPKP1 HGNC:HGNC:42374 +389332 LOC389332 Ensembl:ENSG00000271824|Vega:OTTHUMG00000185564 +389333 PROB1 HGNC:HGNC:41906|Ensembl:ENSG00000228672|Vega:OTTHUMG00000185568 +389336 C5orf46 HGNC:HGNC:33768|Ensembl:ENSG00000178776|Vega:OTTHUMG00000163420 +389337 ARHGEF37 HGNC:HGNC:34430|Ensembl:ENSG00000183111|Vega:OTTHUMG00000163491 +389342 RPL10P9 HGNC:HGNC:35579 +389362 PSMG4 MIM:617550|HGNC:HGNC:21108|Ensembl:ENSG00000180822|Vega:OTTHUMG00000014142 +389376 SFTA2 HGNC:HGNC:18386|Ensembl:ENSG00000196260|Vega:OTTHUMG00000031183 +389383 CLPSL2 HGNC:HGNC:21250|Ensembl:ENSG00000196748|Vega:OTTHUMG00000014581 +389384 C6orf222 HGNC:HGNC:33769|Ensembl:ENSG00000189325|Vega:OTTHUMG00000014591 +389386 LAP3P2 HGNC:HGNC:42365 +389395 HNRNPA3P4 HGNC:HGNC:39773 +389396 GLYATL3 MIM:614763|HGNC:HGNC:21349|Ensembl:ENSG00000203972|Vega:OTTHUMG00000014818 +389400 GFRAL HGNC:HGNC:32789|Ensembl:ENSG00000187871|Vega:OTTHUMG00000014900 +389404 RPL9P18 HGNC:HGNC:36954 +389416 BDH2P1 HGNC:HGNC:21476 +389421 LIN28B MIM:611044|HGNC:HGNC:32207|Ensembl:ENSG00000187772|Vega:OTTHUMG00000015290 +389424 PA2G4P5 HGNC:HGNC:32218 +389428 RPL5P18 HGNC:HGNC:36640 +389432 SAMD5 HGNC:HGNC:21180|Ensembl:ENSG00000203727|Vega:OTTHUMG00000015767 +389434 IYD MIM:612025|HGNC:HGNC:21071|Ensembl:ENSG00000009765|Vega:OTTHUMG00000016347 +389435 RPL27AP6 HGNC:HGNC:35977 +389458 RBAKDN HGNC:HGNC:33770|Ensembl:ENSG00000273313 +389465 LOC389465 - +389472 RPS26P32 HGNC:HGNC:35753 +389473 LOC389473 - +389493 NUPR2 HGNC:HGNC:44164|Ensembl:ENSG00000185290|Vega:OTTHUMG00000156224 +389524 GTF2IRD2B MIM:608900|HGNC:HGNC:33125|Ensembl:ENSG00000174428|Vega:OTTHUMG00000181534 +389537 OR7E38P HGNC:HGNC:8411 +389538 CCZ1P-OR7E38P - +389541 LAMTOR4 HGNC:HGNC:33772|Ensembl:ENSG00000188186|Vega:OTTHUMG00000154854 +389549 FEZF1 MIM:613301|HGNC:HGNC:22788|Ensembl:ENSG00000128610|Vega:OTTHUMG00000157091 +389558 FAM180A HGNC:HGNC:33773|Ensembl:ENSG00000189320|Vega:OTTHUMG00000155537 +389599 STRADBP1 HGNC:HGNC:22478 +389602 LOC389602 - +389610 XKR5 HGNC:HGNC:20782|Ensembl:ENSG00000275591|Vega:OTTHUMG00000153652 +389611 FAM90A3P MIM:613042|HGNC:HGNC:32251 +389616 OR7E125P HGNC:HGNC:15098 +389618 FAM90A6P HGNC:HGNC:32254 +389626 OR7E161P HGNC:HGNC:31234 +389630 FAM90A15P MIM:613051|HGNC:HGNC:32263 +389631 ZNF705CP HGNC:HGNC:32283 +389633 FAM90A25P HGNC:HGNC:32246 +389634 LINC00937 HGNC:HGNC:48629|Ensembl:ENSG00000226091 +389641 LOC389641 Ensembl:ENSG00000246582 +389643 NUGGC HGNC:HGNC:33550|Ensembl:ENSG00000189233|Vega:OTTHUMG00000155970 +389644 RPL5P22 HGNC:HGNC:35695 +389649 C8orf86 HGNC:HGNC:33774|Ensembl:ENSG00000196166|Vega:OTTHUMG00000163992 +389652 ASNSP1 HGNC:HGNC:754 +389655 RPL29P19 HGNC:HGNC:35508 +389658 ALKAL1 HGNC:HGNC:33775|Ensembl:ENSG00000196711|Vega:OTTHUMG00000164256 +389662 SEPT10P1 HGNC:HGNC:40018 +389668 XKR9 HGNC:HGNC:20937|Ensembl:ENSG00000221947|Vega:OTTHUMG00000164431 +389672 RPSAP47 HGNC:HGNC:36162 +389674 HNRNPA1P4 HGNC:HGNC:32234 +389676 C8orf87 HGNC:HGNC:42974 +389677 RBM12B HGNC:HGNC:32310|Ensembl:ENSG00000183808|Vega:OTTHUMG00000164317 +389690 MROH5 HGNC:HGNC:42976|Ensembl:ENSG00000226807|Vega:OTTHUMG00000155944 +389692 MAFA MIM:610303|HGNC:HGNC:23145|Ensembl:ENSG00000182759|Vega:OTTHUMG00000165037 +389705 LOC389705 - +389715 FAM205BP HGNC:HGNC:24504 +389727 FKBP4P2 HGNC:HGNC:50371 +389730 SPATA31A6 HGNC:HGNC:32006|Ensembl:ENSG00000185775|Vega:OTTHUMG00000013224 +389740 ADGRF5P1 HGNC:HGNC:32922 +389741 GLIDR HGNC:HGNC:48823|Ensembl:ENSG00000278175 +389747 MEP1AP3 HGNC:HGNC:39137 +389756 AQP7P2 HGNC:HGNC:32049 +389761 SPATA31D4 HGNC:HGNC:38601|Ensembl:ENSG00000189357|Vega:OTTHUMG00000020088 +389762 SPATA31D3 HGNC:HGNC:38603|Ensembl:ENSG00000186788|Vega:OTTHUMG00000020084 +389763 SPATA31D1 HGNC:HGNC:37283|Ensembl:ENSG00000214929|Vega:OTTHUMG00000169122 +389765 LOC389765 - +389766 C9orf153 HGNC:HGNC:31456|Ensembl:ENSG00000187753|Vega:OTTHUMG00000020134 +389768 LOC389768 - +389787 TPT1P9 HGNC:HGNC:49299 +389791 PTGES2-AS1 HGNC:HGNC:48711|Ensembl:ENSG00000232850 +389792 IER5L HGNC:HGNC:23679|Ensembl:ENSG00000188483|Vega:OTTHUMG00000020773 +389799 CFAP77 HGNC:HGNC:33776|Ensembl:ENSG00000188523|Vega:OTTHUMG00000131684 +389812 LCN15 HGNC:HGNC:33777|Ensembl:ENSG00000177984|Vega:OTTHUMG00000020943 +389813 C9orf172 HGNC:HGNC:37284|Ensembl:ENSG00000232434|Vega:OTTHUMG00000187258 +389816 LRRC26 MIM:613505|HGNC:HGNC:31409|Ensembl:ENSG00000184709|Vega:OTTHUMG00000020980 +389827 MYMK MIM:615345|HGNC:HGNC:33778|Ensembl:ENSG00000187616|Vega:OTTHUMG00000131685 +389831 LOC389831 Ensembl:ENSG00000276256 +389834 LOC389834 - +389840 MAP3K15 MIM:300820|HGNC:HGNC:31689|Ensembl:ENSG00000180815|Vega:OTTHUMG00000022724 +389842 LOC389842 - +389844 FTH1P19 HGNC:HGNC:33525 +389849 GAPDHP65 HGNC:HGNC:4143 +389852 SPACA5 MIM:300593|HGNC:HGNC:31353|Ensembl:ENSG00000171489|Vega:OTTHUMG00000021459 +389856 USP27X MIM:300975|HGNC:HGNC:13486|Ensembl:ENSG00000273820|Vega:OTTHUMG00000189037 +389857 CENPVL1 HGNC:HGNC:31851|Ensembl:ENSG00000223591|Vega:OTTHUMG00000021539 +389860 PAGE2B HGNC:HGNC:31805|Ensembl:ENSG00000238269|Vega:OTTHUMG00000021645 +389866 SERBP1P1 HGNC:HGNC:32247 +389873 SEPHS1P4 HGNC:HGNC:42169 +389874 ZCCHC13 HGNC:HGNC:31749|Ensembl:ENSG00000187969|Vega:OTTHUMG00000021851 +389884 PA2G4P1 HGNC:HGNC:8551 +389895 LOC389895 - +389898 UBE2NL HGNC:HGNC:31710|Ensembl:ENSG00000276380|Vega:OTTHUMG00000188525 +389901 XRCC6P2 HGNC:HGNC:45184 +389903 CSAG3 HGNC:HGNC:26237|Ensembl:ENSG00000268916 +389906 LOC389906 - +389932 AKR1C6P HGNC:HGNC:44680 +389935 PRPF38AP1 HGNC:HGNC:44692 +389941 C1QL3 MIM:615227|HGNC:HGNC:19359|Ensembl:ENSG00000165985|Vega:OTTHUMG00000017738 +389948 MKNK2P1 HGNC:HGNC:44970 +389970 GAPDHP21 HGNC:HGNC:37773 +389976 ACTBP14 HGNC:HGNC:45086 +389990 RPA2P2 HGNC:HGNC:45117 +389992 RPL7P34 HGNC:HGNC:36181 +389997 NIP7P1 HGNC:HGNC:45180 +390003 GUCY2GP HGNC:HGNC:31863|Ensembl:ENSG00000243316 +390006 PPIAP19 HGNC:HGNC:31663 +390007 TOMM22P5 HGNC:HGNC:38741 +390010 NKX1-2 HGNC:HGNC:31652|Ensembl:ENSG00000229544|Vega:OTTHUMG00000185174 +390012 OR6L1P HGNC:HGNC:15124 +390028 OR4F2P HGNC:HGNC:8299 +390029 LOC390029 - +390030 OR55B1P HGNC:HGNC:15241 +390031 SSU72P2 HGNC:HGNC:43621 +390033 SSU72P7 HGNC:HGNC:43626 +390034 OR51R1P HGNC:HGNC:15203 +390035 OR52K3P HGNC:HGNC:15224 +390036 OR52K1 HGNC:HGNC:15222|Ensembl:ENSG00000196778|Vega:OTTHUMG00000165705 +390037 OR52I1 HGNC:HGNC:15220|Ensembl:ENSG00000232268|Vega:OTTHUMG00000165722 +390038 OR51D1 HGNC:HGNC:15193|Ensembl:ENSG00000197428|Vega:OTTHUMG00000165724 +390039 OR51A9P HGNC:HGNC:15190 +390040 OR51F5P HGNC:HGNC:31283 +390041 OR51C4P HGNC:HGNC:31280 +390043 OR51F3P HGNC:HGNC:31281 +390044 OR51F4P HGNC:HGNC:31282 +390046 OR51A6P HGNC:HGNC:15187 +390053 OR52A4P HGNC:HGNC:19579 +390054 OR52A5 HGNC:HGNC:19580|Ensembl:ENSG00000171944|Vega:OTTHUMG00000066616 +390058 OR51B6 HGNC:HGNC:19600|Ensembl:ENSG00000176239|Vega:OTTHUMG00000066669 +390059 OR51M1 HGNC:HGNC:14847|Ensembl:ENSG00000184698|Vega:OTTHUMG00000066680 +390061 OR51Q1 HGNC:HGNC:14851|Ensembl:ENSG00000167360|Vega:OTTHUMG00000066896 +390063 OR51I1 HGNC:HGNC:15200|Ensembl:ENSG00000167359|Vega:OTTHUMG00000066908 +390064 OR51I2 HGNC:HGNC:15201|Ensembl:ENSG00000187918|Vega:OTTHUMG00000066902 +390066 OR52D1 HGNC:HGNC:15212|Ensembl:ENSG00000181609|Vega:OTTHUMG00000066895 +390067 OR52H1 HGNC:HGNC:15218|Ensembl:ENSG00000181616|Vega:OTTHUMG00000066909 +390072 OR52N4 HGNC:HGNC:15230|Ensembl:ENSG00000181074|Vega:OTTHUMG00000066887 +390073 OR56B2P HGNC:HGNC:15246 +390075 OR52N5 HGNC:HGNC:15231|Ensembl:ENSG00000181009|Vega:OTTHUMG00000168799 +390077 OR52N2 HGNC:HGNC:15228|Ensembl:ENSG00000180988|Vega:OTTHUMG00000168801 +390078 OR52E6 HGNC:HGNC:15215|Ensembl:ENSG00000205409|Vega:OTTHUMG00000168802 +390079 OR52E8 HGNC:HGNC:15217|Ensembl:ENSG00000183269|Vega:OTTHUMG00000168803 +390081 OR52E4 HGNC:HGNC:15213|Ensembl:ENSG00000180974|Vega:OTTHUMG00000168804 +390082 OR52E5 HGNC:HGNC:15214 +390083 OR56A3 HGNC:HGNC:14786|Ensembl:ENSG00000184478|Vega:OTTHUMG00000165373 +390084 OR56A5 HGNC:HGNC:14792|Ensembl:ENSG00000188691|Vega:OTTHUMG00000165730 +390091 OR10AB1P HGNC:HGNC:14804 +390093 OR10A6 HGNC:HGNC:15132|Ensembl:ENSG00000279000 +390098 LOC390098 - +390099 LOC390099 - +390101 LOC390101 - +390102 PCNAP4 HGNC:HGNC:43737 +390107 RPS24P15 HGNC:HGNC:35665 +390110 ACCSL HGNC:HGNC:34391|Ensembl:ENSG00000205126|Vega:OTTHUMG00000166426 +390113 OR4X1 HGNC:HGNC:14854|Ensembl:ENSG00000176567|Vega:OTTHUMG00000165301 +390116 OR4A40P HGNC:HGNC:31259 +390117 OR4A43P HGNC:HGNC:31262 +390131 OR4A6P HGNC:HGNC:15163 +390133 OR4A2P HGNC:HGNC:15159 +390134 OR4A4P HGNC:HGNC:15161 +390136 OR4A11P HGNC:HGNC:15148 +390137 OR4A9P HGNC:HGNC:15166 +390138 OR4A10P HGNC:HGNC:15147 +390139 OR4A17P HGNC:HGNC:15154 +390142 OR5D13 HGNC:HGNC:15280|Ensembl:ENSG00000279761|Vega:OTTHUMG00000166807 +390144 OR5D16 HGNC:HGNC:15283|Ensembl:ENSG00000205029|Vega:OTTHUMG00000154233 +390148 OR5W2 HGNC:HGNC:15299|Ensembl:ENSG00000187612|Vega:OTTHUMG00000166818 +390151 OR8H2 HGNC:HGNC:15308|Ensembl:ENSG00000181767|Vega:OTTHUMG00000166832 +390152 OR8H3 HGNC:HGNC:15309|Ensembl:ENSG00000181761|Vega:OTTHUMG00000166833 +390154 OR5T3 HGNC:HGNC:15297|Ensembl:ENSG00000172489|Vega:OTTHUMG00000166852 +390155 OR5T1 HGNC:HGNC:14821|Ensembl:ENSG00000181698|Vega:OTTHUMG00000166853 +390157 OR8K1 HGNC:HGNC:14831|Ensembl:ENSG00000150261|Vega:OTTHUMG00000166858 +390158 RPL5P29 HGNC:HGNC:36335 +390162 OR5M9 HGNC:HGNC:15294|Ensembl:ENSG00000150269|Vega:OTTHUMG00000166874 +390166 OR5M5P HGNC:HGNC:14810 +390167 OR5M10 HGNC:HGNC:15290|Ensembl:ENSG00000254834|Vega:OTTHUMG00000166862 +390168 OR5M1 HGNC:HGNC:8352|Ensembl:ENSG00000255012|Vega:OTTHUMG00000166863 +390174 OR9G1 HGNC:HGNC:15319|Ensembl:ENSG00000174914|Vega:OTTHUMG00000167112 +390181 OR5AK2 HGNC:HGNC:15251|Ensembl:ENSG00000181273|Vega:OTTHUMG00000167019 +390183 RPS4XP13 HGNC:HGNC:36522 +390186 OR5B10P HGNC:HGNC:8320 +390190 OR5B2 HGNC:HGNC:8323|Ensembl:ENSG00000172365|Vega:OTTHUMG00000167517 +390191 OR5B12 HGNC:HGNC:15432|Ensembl:ENSG00000172362|Vega:OTTHUMG00000167543 +390195 OR5AN1 MIM:615702|HGNC:HGNC:15255|Ensembl:ENSG00000176495|Vega:OTTHUMG00000167337 +390197 OR4D10 HGNC:HGNC:15173|Ensembl:ENSG00000254466|Vega:OTTHUMG00000167341 +390199 OR4D9 HGNC:HGNC:15178|Ensembl:ENSG00000172742|Vega:OTTHUMG00000167343 +390201 OR10V1 HGNC:HGNC:15136|Ensembl:ENSG00000172289|Vega:OTTHUMG00000167406 +390203 SRD5A3P1 HGNC:HGNC:49243 +390205 LRRC10B HGNC:HGNC:37215|Ensembl:ENSG00000204950|Vega:OTTHUMG00000168178 +390206 RPS2P37 HGNC:HGNC:36482 +390211 KRT8P26 HGNC:HGNC:33378 +390212 GPR152 HGNC:HGNC:23622|Ensembl:ENSG00000175514|Vega:OTTHUMG00000168032 +390213 DOC2GP HGNC:HGNC:37962 +390215 OR7E145P HGNC:HGNC:19618 +390218 IFITM9P HGNC:HGNC:33972 +390221 FOLR1P1 HGNC:HGNC:3792 +390224 OR2AT2P HGNC:HGNC:19619 +390225 OR2AT1P HGNC:HGNC:15145 +390226 GUCY2EP MIM:601138|HGNC:HGNC:4690 +390228 RPL7AP54 HGNC:HGNC:36264 +390231 TRIM77 HGNC:HGNC:34228|Ensembl:ENSG00000214414|Vega:OTTHUMG00000167624 +390233 TRIM64FP HGNC:HGNC:43976 +390239 NDUFB11P1 HGNC:HGNC:33980 +390243 IZUMO1R MIM:615737|HGNC:HGNC:32565|Ensembl:ENSG00000183560|Vega:OTTHUMG00000167776 +390245 KDM4E MIM:616581|HGNC:HGNC:37098|Ensembl:ENSG00000235268|Vega:OTTHUMG00000167858 +390250 LOC390250 - +390251 LOC390251 - +390255 LOC390255 - +390259 BSX MIM:611074|HGNC:HGNC:20450|Ensembl:ENSG00000188909|Vega:OTTHUMG00000150247 +390260 OR6X1 HGNC:HGNC:14737|Ensembl:ENSG00000221931|Vega:OTTHUMG00000166011 +390261 OR6M1 HGNC:HGNC:14711|Ensembl:ENSG00000196099|Vega:OTTHUMG00000166012 +390264 OR10G4 HGNC:HGNC:14809|Ensembl:ENSG00000254737|Vega:OTTHUMG00000165966 +390265 OR10G7 HGNC:HGNC:14842|Ensembl:ENSG00000182634|Vega:OTTHUMG00000165969 +390266 OR10D4P HGNC:HGNC:14770 +390267 OR10N1P HGNC:HGNC:14689 +390269 OR8F1P HGNC:HGNC:14691 +390271 OR8B3 HGNC:HGNC:8472|Ensembl:ENSG00000196661|Vega:OTTHUMG00000165983 +390273 OR8A2P HGNC:HGNC:15306 +390274 OR8B10P HGNC:HGNC:14751 +390275 OR8A1 HGNC:HGNC:8469|Ensembl:ENSG00000196119|Vega:OTTHUMG00000165923 +390282 LOC390282 - +390283 RPL31P10 HGNC:HGNC:33180 +390284 SRP14P1 HGNC:HGNC:33181 +390288 OR7E84P HGNC:HGNC:14690 +390294 HNRNPABP1 HGNC:HGNC:48744 +390297 PSMC1P8 HGNC:HGNC:39783 +390298 TIMM17BP1 HGNC:HGNC:49865 +390301 ST13P9 HGNC:HGNC:38744 +390306 LOC390306 - +390308 LOC390308 - +390311 PHBP18 HGNC:HGNC:51551 +390313 OR5BS1P HGNC:HGNC:19627 +390314 LOC390314 - +390318 OR10U1P HGNC:HGNC:15332 +390320 OR6C5P HGNC:HGNC:31292 +390321 OR6C1 HGNC:HGNC:8355|Ensembl:ENSG00000205330|Vega:OTTHUMG00000168102 +390322 OR6C7P HGNC:HGNC:31306 +390323 OR6C75 HGNC:HGNC:31304|Ensembl:ENSG00000187857|Vega:OTTHUMG00000169886 +390324 OR6C71P HGNC:HGNC:31300 +390326 OR6C76 HGNC:HGNC:31305|Ensembl:ENSG00000185821|Vega:OTTHUMG00000169956 +390327 OR6C70 HGNC:HGNC:31299|Ensembl:ENSG00000184954|Vega:OTTHUMG00000171127 +390329 OR6U2P HGNC:HGNC:19631 +390332 LOC390332 - +390340 PDCL3P7 HGNC:HGNC:44508 +390345 RPL10P13 HGNC:HGNC:52346 +390352 EEF1A1P33 HGNC:HGNC:37911 +390354 RPL18AP3 HGNC:HGNC:31387 +390358 LOC390358 - +390363 CLIC1P1 HGNC:HGNC:32691 +390378 PPIAP28 HGNC:HGNC:39902 +390394 EIF4A1P5 HGNC:HGNC:37924 +390402 AKR1B1P4 HGNC:HGNC:423 +390403 FAM206BP HGNC:HGNC:39851 +390407 EIF4A1P6 HGNC:HGNC:37925 +390411 NPM1P22 HGNC:HGNC:39679 +390413 RPL7P44 HGNC:HGNC:36143 +390415 CCT5P2 HGNC:HGNC:35139 +390418 KRT18P27 HGNC:HGNC:33396 +390419 PPIAP23 HGNC:HGNC:39268 +390421 GAPDHP22 HGNC:HGNC:37774 +390423 ARF4P3 HGNC:HGNC:32380 +390424 ATP5G1P5 HGNC:HGNC:39508 +390429 OR4N2 HGNC:HGNC:14742|Ensembl:ENSG00000176294|Vega:OTTHUMG00000170614 +390431 OR4K2 HGNC:HGNC:14728|Ensembl:ENSG00000165762|Vega:OTTHUMG00000170624 +390432 OR4Q2 HGNC:HGNC:15359|Vega:OTTHUMG00000168643 +390433 OR4K13 HGNC:HGNC:15351|Ensembl:ENSG00000176253|Vega:OTTHUMG00000170781 +390434 OR4U1P HGNC:HGNC:15361 +390435 OR4T1P HGNC:HGNC:15360 +390436 OR4K17 HGNC:HGNC:15355|Ensembl:ENSG00000176230|Vega:OTTHUMG00000170783 +390437 OR4N5 HGNC:HGNC:15358|Ensembl:ENSG00000184394|Vega:OTTHUMG00000170784 +390438 OR11G1P HGNC:HGNC:15345 +390439 OR11G2 HGNC:HGNC:15346|Ensembl:ENSG00000196832|Vega:OTTHUMG00000167700 +390440 OR11H5P HGNC:HGNC:15348 +390441 OR11H7 HGNC:HGNC:15350|Vega:OTTHUMG00000170851 +390442 OR11H4 HGNC:HGNC:15347|Ensembl:ENSG00000176198|Vega:OTTHUMG00000170852 +390443 RNASE9 MIM:614014|HGNC:HGNC:20673|Ensembl:ENSG00000188655|Vega:OTTHUMG00000170989 +390445 OR5AU1 HGNC:HGNC:15362|Ensembl:ENSG00000169327|Vega:OTTHUMG00000170753 +390472 KRT8P2 HGNC:HGNC:20282 +390482 AKR1B1P5 HGNC:HGNC:20002 +390483 SALL4P7 HGNC:HGNC:43900 +390501 MPPE1P1 HGNC:HGNC:20143 +390502 SERPINA2 MIM:107410|HGNC:HGNC:8985|Ensembl:ENSG00000258597|Vega:OTTHUMG00000171347 +390503 ADIPOR1P2 HGNC:HGNC:44911 +390530 IGHV1OR21-1 HGNC:HGNC:38040|IMGT/GENE-DB:IGHV1/OR21-1 +390531 IGHV1OR15-9 HGNC:HGNC:5569|IMGT/GENE-DB:IGHV1/OR15-9 +390535 GOLGA8EP HGNC:HGNC:32377 +390538 OR4M2 HGNC:HGNC:15373|Ensembl:ENSG00000274102|Vega:OTTHUMG00000171738 +390539 OR4N3P HGNC:HGNC:15374|Ensembl:ENSG00000259435 +390560 DNM1DN4-1 - +390561 HERC2P10 HGNC:HGNC:39056 +390572 PRELID1P4 HGNC:HGNC:43889 +390576 RPS15P8 HGNC:HGNC:35847 +390578 RPLP0P10 HGNC:HGNC:35991 +390581 ATP5HP1 HGNC:HGNC:31021 +390586 LOC390586 - +390594 KBTBD13 MIM:613727|HGNC:HGNC:37227|Ensembl:ENSG00000234438|Vega:OTTHUMG00000172424 +390595 UBAP1L HGNC:HGNC:40028|Ensembl:ENSG00000246922|Vega:OTTHUMG00000172425 +390597 LETM1P1 HGNC:HGNC:14649 +390598 SKOR1 MIM:611273|HGNC:HGNC:21326|Ensembl:ENSG00000188779|Vega:OTTHUMG00000170878 +390600 LOC390600 - +390601 KRT8P9 HGNC:HGNC:33363 +390610 KRT8P23 HGNC:HGNC:33375 +390612 RPL18P11 HGNC:HGNC:35742 +390614 LOC390614 - +390616 ANKRD34C HGNC:HGNC:33888|Ensembl:ENSG00000235711|Vega:OTTHUMG00000172072 +390617 LOC390617 - +390618 LOC390618 - +390627 CSPG4P10 HGNC:HGNC:48361 +390634 KRT18P47 HGNC:HGNC:33417 +390637 GDPGP1 HGNC:HGNC:34360|Ensembl:ENSG00000183208|Vega:OTTHUMG00000172128 +390638 LOC390638 - +390643 PGAM1P12 HGNC:HGNC:42459 +390648 OR4F6 HGNC:HGNC:15372|Ensembl:ENSG00000184140|Vega:OTTHUMG00000172267 +390649 OR4F15 HGNC:HGNC:15078|Ensembl:ENSG00000182854|Vega:OTTHUMG00000172268 +390650 OR4F14P HGNC:HGNC:15077 +390651 OR4F13P HGNC:HGNC:15076|Ensembl:ENSG00000214344 +390652 OR4F28P HGNC:HGNC:31229 +390660 ADAMTS7P1 HGNC:HGNC:49407|Ensembl:ENSG00000274376 +390664 C1QTNF8 MIM:614147|HGNC:HGNC:31374|Ensembl:ENSG00000184471|Vega:OTTHUMG00000167756 +390667 PTX4 MIM:613442|HGNC:HGNC:14171|Ensembl:ENSG00000251692 +390671 RPL18P12 HGNC:HGNC:36115 +390688 CDC37P1 HGNC:HGNC:34406 +390705 LOC390705 - +390714 LOC390714 - +390729 RPL10P14 HGNC:HGNC:43897 +390730 PHBP21 HGNC:HGNC:51554 +390732 CES1P2 HGNC:HGNC:48928 +390735 RPS15AP34 HGNC:HGNC:35609 +390739 LOC390739 - +390748 PABPN1L HGNC:HGNC:37237|Ensembl:ENSG00000205022|Vega:OTTHUMG00000170127 +390756 OR3A4P HGNC:HGNC:15510|Ensembl:ENSG00000279517 +390766 RNASEH1P2 HGNC:HGNC:18715 +390788 CCL3P1 MIM:609467|HGNC:HGNC:10629 +390790 ARL5C HGNC:HGNC:31111|Ensembl:ENSG00000141748|Vega:OTTHUMG00000179048 +390791 LOC390791 - +390792 KRT39 MIM:616678|HGNC:HGNC:32971|Ensembl:ENSG00000196859|Vega:OTTHUMG00000133424 +390800 RPL7L1P5 HGNC:HGNC:39487 +390806 LOC390806 - +390811 POLR3KP2 HGNC:HGNC:39578 +390816 THA1P HGNC:HGNC:18004 +390831 PMM2P1 HGNC:HGNC:9116 +390834 FEM1AP2 HGNC:HGNC:39830 +390836 OR4K8P HGNC:HGNC:14787 +390843 EIF4A3P1 HGNC:HGNC:51460 +390844 ARIH2P1 HGNC:HGNC:31732 +390846 LOC390846 - +390848 RPS15AP35 HGNC:HGNC:36768 +390856 RPL29P32 HGNC:HGNC:35834 +390857 RPSAP57 HGNC:HGNC:35889 +390858 OACYLP HGNC:HGNC:44362 +390860 LOC390860 - +390872 OR4F8P HGNC:HGNC:15395 +390874 ONECUT3 MIM:611294|HGNC:HGNC:13399|Ensembl:ENSG00000205922|Vega:OTTHUMG00000172429 +390876 LOC390876 - +390877 LOC390877 - +390882 OR7G2 HGNC:HGNC:8466|Ensembl:ENSG00000170923|Vega:OTTHUMG00000179931 +390883 OR7G3 HGNC:HGNC:8467|Ensembl:ENSG00000170920|Vega:OTTHUMG00000165520 +390885 OR7E18P HGNC:HGNC:8389 +390886 OR7H1P HGNC:HGNC:8468 +390892 OR7A10 HGNC:HGNC:8356|Ensembl:ENSG00000127515|Vega:OTTHUMG00000183412 +390894 OR7A2P HGNC:HGNC:8370 +390895 OR7A1P HGNC:HGNC:8364 +390904 KRT18P40 HGNC:HGNC:33409 +390916 NUDT19 HGNC:HGNC:32036|Ensembl:ENSG00000213965|Vega:OTTHUMG00000180228 +390924 EEF1A1P7 HGNC:HGNC:3202 +390927 ZNF793 HGNC:HGNC:33115|Ensembl:ENSG00000188227|Vega:OTTHUMG00000182003 +390928 ACP7 MIM:610490|HGNC:HGNC:33781|Ensembl:ENSG00000183760|Vega:OTTHUMG00000182799 +390933 LOC390933 - +390937 LOC390937 Ensembl:ENSG00000268041 +390940 PINLYP HGNC:HGNC:44206|Ensembl:ENSG00000234465|Vega:OTTHUMG00000175560 +390948 HNRNPMP2 HGNC:HGNC:48746 +390949 RPL23AP80 HGNC:HGNC:36956 +390956 LOC390956 - +390963 ZNF818P HGNC:HGNC:33265 +390980 ZNF805 HGNC:HGNC:23272|Ensembl:ENSG00000204524|Vega:OTTHUMG00000183219 +390992 HES3 MIM:609971|HGNC:HGNC:26226|Ensembl:ENSG00000173673|Vega:OTTHUMG00000001271 +390993 RPL7AP18 HGNC:HGNC:35613 +390996 CFL1P6 HGNC:HGNC:34545 +390997 LOC390997 - +390998 RPL10P17 HGNC:HGNC:52348 +390999 PRAMEF12 HGNC:HGNC:22125|Ensembl:ENSG00000116726|Vega:OTTHUMG00000001927 +391002 PRAMEF8 HGNC:HGNC:24074|Ensembl:ENSG00000182330|Vega:OTTHUMG00000008037 +391003 PRAMEF18 HGNC:HGNC:30693|Ensembl:ENSG00000279804 +391004 PRAMEF17 HGNC:HGNC:29485|Ensembl:ENSG00000204479|Vega:OTTHUMG00000007909 +391012 DYNLL1P3 HGNC:HGNC:49654 +391013 PLA2G2C HGNC:HGNC:9032|Ensembl:ENSG00000187980|Vega:OTTHUMG00000002705 +391019 RPL29P6 HGNC:HGNC:36627 +391020 LOC391020 - +391026 ACTN4P2 HGNC:HGNC:44032 +391033 MKRN8P HGNC:HGNC:7120 +391037 SKINT1L MIM:616392|HGNC:HGNC:33993 +391039 CFL1P2 HGNC:HGNC:1878 +391040 BTF3L4P3 HGNC:HGNC:39647 +391044 PHBP3 HGNC:HGNC:8915 +391045 SLC2A3P2 HGNC:HGNC:31074 +391048 LOC391048 - +391051 UOX MIM:191540|HGNC:HGNC:12575 +391053 CAPNS1P1 HGNC:HGNC:39562 +391059 FRRS1 MIM:611578|HGNC:HGNC:27622|Ensembl:ENSG00000156869|Vega:OTTHUMG00000010768 +391069 GAPDHP64 HGNC:HGNC:4158 +391073 GAPDHP74 HGNC:HGNC:50647 +391075 GAPDHP23 HGNC:HGNC:37775 +391076 HSD3BP1 HGNC:HGNC:5219 +391077 GAPDHP58 HGNC:HGNC:4142 +391081 HSD3BP5 HGNC:HGNC:5223 +391092 LOC391092 - +391099 KRT8P28 HGNC:HGNC:33380 +391102 RPLP0P4 HGNC:HGNC:36489 +391104 VHLL HGNC:HGNC:30666|Ensembl:ENSG00000189030|Vega:OTTHUMG00000024058 +391106 VDAC1P9 HGNC:HGNC:37484 +391107 OR10K2 HGNC:HGNC:14826|Ensembl:ENSG00000180708|Vega:OTTHUMG00000019638 +391109 OR10K1 HGNC:HGNC:14693|Ensembl:ENSG00000173285|Vega:OTTHUMG00000017517 +391110 OR10R3P HGNC:HGNC:14829 +391112 OR6Y1 HGNC:HGNC:14823|Ensembl:ENSG00000197532|Vega:OTTHUMG00000019629 +391114 OR6K3 HGNC:HGNC:15030|Ensembl:ENSG00000203757|Vega:OTTHUMG00000022770 +391115 OR6K5P HGNC:HGNC:15032 +391117 OR10J2P HGNC:HGNC:14991 +391119 OR10J7P HGNC:HGNC:19637 +391120 OR10J9P HGNC:HGNC:19639 +391121 OR10J4 HGNC:HGNC:15408|Vega:OTTHUMG00000022740 +391123 VSIG8 HGNC:HGNC:32063|Ensembl:ENSG00000243284|Vega:OTTHUMG00000168834 +391124 RPL27AP2 HGNC:HGNC:36238 +391126 RPL26P12 HGNC:HGNC:36025 +391130 RPS17P6 HGNC:HGNC:36945 +391135 RPL4P3 HGNC:HGNC:35773 +391136 LOC391136 - +391137 RPS15P3 HGNC:HGNC:35563 +391139 GOT2P2 HGNC:HGNC:4435 +391140 RPL13P7 HGNC:HGNC:35510 +391151 RPL10P4 HGNC:HGNC:52342 +391155 KRT8P29 HGNC:HGNC:33381 +391158 TFDP1P HGNC:HGNC:11750 +391160 ARPC3P2 HGNC:HGNC:39431 +391162 GAPDHP24 HGNC:HGNC:37776 +391165 RPS26P17 HGNC:HGNC:36681 +391168 RPS3AP7 HGNC:HGNC:36376 +391169 CDKN2AIPNLP1 HGNC:HGNC:39854 +391171 TUBB8P10 HGNC:HGNC:42348 +391174 FAM96AP2 HGNC:HGNC:43862 +391175 RPL23AP15 HGNC:HGNC:36486 +391179 KRT18P32 HGNC:HGNC:33401 +391181 RPL6P3 HGNC:HGNC:35925 +391183 RSL24D1P4 HGNC:HGNC:37884 +391189 OR11L1 HGNC:HGNC:14998|Ensembl:ENSG00000197591|Vega:OTTHUMG00000040193 +391190 OR2L8 HGNC:HGNC:15014|Ensembl:ENSG00000279263|Vega:OTTHUMG00000040196 +391191 OR2AK2 HGNC:HGNC:19569|Ensembl:ENSG00000187080|Vega:OTTHUMG00000040201 +391192 OR2L3 HGNC:HGNC:15009|Ensembl:ENSG00000198128|Vega:OTTHUMG00000040195 +391194 OR2M2 HGNC:HGNC:8268|Ensembl:ENSG00000198601|Vega:OTTHUMG00000040460 +391195 OR2T33 HGNC:HGNC:31255|Ensembl:ENSG00000177212|Vega:OTTHUMG00000040458 +391196 OR2M7 HGNC:HGNC:19594|Ensembl:ENSG00000177186|Vega:OTTHUMG00000040461 +391211 OR2G6 HGNC:HGNC:27019|Ensembl:ENSG00000188558|Vega:OTTHUMG00000040462 +391239 LOC391239 - +391242 PUDPP3 HGNC:HGNC:38118 +391247 LOC391247 - +391253 SPINT4 HGNC:HGNC:16130|Ensembl:ENSG00000149651|Vega:OTTHUMG00000130153 +391256 KRT18P4 HGNC:HGNC:16604 +391257 SUMO1P1 HGNC:HGNC:33148 +391266 CNN2P7 HGNC:HGNC:39532 +391267 ANKRD20A11P HGNC:HGNC:42024|Ensembl:ENSG00000215559 +391269 ANKRD20A18P HGNC:HGNC:23756 +391276 THUMPD1P1 HGNC:HGNC:23808 +391279 OR7E23P HGNC:HGNC:8395 +391282 RPL23AP12 HGNC:HGNC:23840 +391322 LOC391322 - +391334 LOC391334 - +391349 PIK3CDP1 HGNC:HGNC:52629 +391356 PTRHD1 MIM:617342|HGNC:HGNC:33782|Ensembl:ENSG00000184924|Vega:OTTHUMG00000151978 +391358 TRMT112P6 HGNC:HGNC:44025 +391359 LOC391359 - +391365 SULT6B1 MIM:617152|HGNC:HGNC:33433|Ensembl:ENSG00000138068|Vega:OTTHUMG00000152160 +391367 GAPDHP25 HGNC:HGNC:37777 +391370 RPS12P4 HGNC:HGNC:35670 +391378 HNRNPA1P66 HGNC:HGNC:48796 +391383 LOC391383 - +391387 RPSAP28 HGNC:HGNC:35612 +391428 SEPHS1P7 HGNC:HGNC:42167 +391436 MED15P5 HGNC:HGNC:48654 +391448 LOC391448 - +391458 KRT18P46 HGNC:HGNC:33416 +391462 RPSAP24 HGNC:HGNC:36362 +391465 LOC391465 - +391467 IMPDH1P7 HGNC:HGNC:33962 +391470 AHCYP5 HGNC:HGNC:44997 +391472 BICD1P1 HGNC:HGNC:51374 +391475 DYTN HGNC:HGNC:23279|Ensembl:ENSG00000232125|Vega:OTTHUMG00000154729 +391485 KRT8P30 HGNC:HGNC:33382 +391490 RPL23AP26 HGNC:HGNC:35592 +391491 GAMTP1 HGNC:HGNC:33982 +391496 OR5S1P HGNC:HGNC:15040 +391504 RPL23AP38 HGNC:HGNC:36351 +391508 PGAM1P4 HGNC:HGNC:42451 +391518 VENTXP7 HGNC:HGNC:13638 +391524 THRAP3P1 HGNC:HGNC:32386 +391526 IGBP1P3 HGNC:HGNC:43612 +391530 SALL4P6 HGNC:HGNC:39823 +391532 LOC391532 - +391533 FLT1P1 HGNC:HGNC:44609 +391538 ALDOAP1 HGNC:HGNC:415 +391539 RPS25P4 HGNC:HGNC:35669 +391548 OR7E55P HGNC:HGNC:8430 +391552 AGGF1P3 HGNC:HGNC:38053 +391556 LOC391556 - +391559 VTI1BP1 HGNC:HGNC:43727 +391560 RPL32P7 HGNC:HGNC:35804 +391562 LOC391562 - +391566 LOC391566 - +391576 OR7E129P HGNC:HGNC:15052 +391578 LOC391578 - +391581 RPL31P23 HGNC:HGNC:36096 +391584 KRT18P35 HGNC:HGNC:33404 +391587 LOC391587 - +391589 KRT18P34 HGNC:HGNC:33403 +391592 BZW1P1 HGNC:HGNC:31378 +391595 RPL32P10 HGNC:HGNC:35641 +391598 RPSAP31 HGNC:HGNC:35558 +391600 LOC391600 - +391603 NMNAT1P3 HGNC:HGNC:49165 +391622 USP17L6P HGNC:HGNC:37179|Ensembl:ENSG00000205946 +391627 USP17L9P MIM:607011|HGNC:HGNC:12615|Ensembl:ENSG00000251694 +391630 OR7E83P HGNC:HGNC:14688 +391632 OR7E35P HGNC:HGNC:8408 +391634 HSP90AB2P HGNC:HGNC:32537 +391636 LOC391636 - +391642 IGBP1P5 HGNC:HGNC:43614 +391647 KRT18P25 HGNC:HGNC:33394 +391655 RPL17P20 HGNC:HGNC:36015 +391656 RPS15AP17 HGNC:HGNC:36888 +391657 DPP3P1 HGNC:HGNC:51349 +391670 HNRNPA1P56 HGNC:HGNC:48786 +391672 IGBP1P4 HGNC:HGNC:43613 +391674 LOC391674 - +391679 RPL6P14 HGNC:HGNC:35661 +391681 EXOC7P1 HGNC:HGNC:43871 +391686 LYPLA1P2 HGNC:HGNC:44006 +391696 TECRP2 HGNC:HGNC:44051 +391697 ZSWIM5P3 HGNC:HGNC:43770 +391698 EEF1GP8 HGNC:HGNC:44563 +391701 RPS23P2 HGNC:HGNC:36568 +391703 KRT18P51 HGNC:HGNC:33421 +391706 RPS3AP18 HGNC:HGNC:35893 +391707 LOC391707 - +391710 LOC391710 - +391711 LOC391711 - +391712 TRIM61 HGNC:HGNC:24339|Ensembl:ENSG00000183439|Vega:OTTHUMG00000161266 +391713 LOC391713 - +391714 TRIM75P HGNC:HGNC:32686 +391718 TSEN2P1 HGNC:HGNC:43965 +391719 RPL19P8 HGNC:HGNC:36696 +391722 MYL12BP2 HGNC:HGNC:51650 +391723 HELT MIM:617546|HGNC:HGNC:33783|Ensembl:ENSG00000187821|Vega:OTTHUMG00000160484 +391738 RPL29P13 HGNC:HGNC:36461 +391739 CCT6P2 HGNC:HGNC:35150 +391741 LOC391741 - +391742 LOC391742 - +391744 LOC391744 - +391746 LOC391746 - +391747 LOC391747 - +391765 LOC391765 - +391768 LOC391768 - +391769 H3.Y - +391771 LOC391771 - +391777 RPS4XP6 HGNC:HGNC:36057 +391798 LOC391798 - +391803 KRT18P45 HGNC:HGNC:33415 +391804 RBMX2P5 HGNC:HGNC:39927 +391811 POLD2P1 HGNC:HGNC:41522 +391813 LOC391813 - +391819 KRT18P42 HGNC:HGNC:33412 +391825 RPL23AP44 HGNC:HGNC:35955 +391827 KRT18P16 HGNC:HGNC:33384 +391828 RPL28P3 HGNC:HGNC:35973 +391833 RPS10P11 HGNC:HGNC:36775 +391834 LOC391834 - +391836 RPL10AP10 HGNC:HGNC:35971 +391845 RPS15P6 HGNC:HGNC:36653 +391850 RPL7AP33 HGNC:HGNC:36679 +392027 LOC392027 - +392100 PSMC1P3 HGNC:HGNC:39778 +392106 OR9A3P HGNC:HGNC:15094 +392132 OR2R1P HGNC:HGNC:8274 +392133 OR10AC1 HGNC:HGNC:14758|Vega:OTTHUMG00000155896 +392138 OR2A25 HGNC:HGNC:19562|Ensembl:ENSG00000221933|Vega:OTTHUMG00000158013 +392140 OR2A13P HGNC:HGNC:15083 +392145 LOC392145 - +392180 LOC392180 - +392181 RPL23AP96 HGNC:HGNC:51631 +392187 LOC392187 - +392188 USP17L8 HGNC:HGNC:37181|Ensembl:ENSG00000237038|Vega:OTTHUMG00000165405 +392193 RPL19P13 HGNC:HGNC:36879 +392194 OR7E158P HGNC:HGNC:31232 +392196 LOC392196 Ensembl:ENSG00000254923 +392197 USP17L7 HGNC:HGNC:37180|Ensembl:ENSG00000226430|Vega:OTTHUMG00000165294 +392206 RPL10AP11 HGNC:HGNC:35875 +392209 HSPA8P11 HGNC:HGNC:44926 +392214 KRT18P37 HGNC:HGNC:33406 +392221 CHCHD2P10 HGNC:HGNC:39593 +392225 PDCL3P1 HGNC:HGNC:31826 +392226 LOC392226 - +392232 LOC392232 - +392242 REXO1L8P HGNC:HGNC:35429 +392255 GDF6 MIM:601147|HGNC:HGNC:4221|Ensembl:ENSG00000156466|Vega:OTTHUMG00000164710 +392256 RPS26P6 HGNC:HGNC:31090 +392262 RPSAP48 HGNC:HGNC:36646 +392264 LOC392264 - +392265 CDK5P1 HGNC:HGNC:21261 +392266 LOC392266 - +392267 IMPDH1P6 HGNC:HGNC:33961 +392268 LOC392268 - +392271 RPL32P20 HGNC:HGNC:35934 +392275 SMPD5 HGNC:HGNC:52275 +392281 GPS2P1 HGNC:HGNC:49622 +392282 RPS5P6 HGNC:HGNC:35960 +392285 PPIAP33 HGNC:HGNC:49752 +392288 MAP1LC3BP1 HGNC:HGNC:49783 +392292 IFNWP5 HGNC:HGNC:5454 +392298 CTAGE12P HGNC:HGNC:37297 +392301 SLC25A5P8 HGNC:HGNC:35469 +392302 ASS1P12 HGNC:HGNC:762 +392305 GLULP4 HGNC:HGNC:4345 +392307 FAM221B HGNC:HGNC:30762|Ensembl:ENSG00000204930|Vega:OTTHUMG00000019880 +392308 OR13E1P HGNC:HGNC:15107 +392309 OR13J1 HGNC:HGNC:15108|Ensembl:ENSG00000168828|Vega:OTTHUMG00000019879 +392310 PGAM1P2 HGNC:HGNC:42449 +392311 OR13C6P HGNC:HGNC:15101 +392313 OR2S1P HGNC:HGNC:8275 +392322 ATP5A1P8 HGNC:HGNC:37666 +392334 LOC392334 - +392335 MYO5BP2 HGNC:HGNC:38496 +392343 CNN2P3 HGNC:HGNC:39528 +392350 BTF3P4 HGNC:HGNC:38566 +392352 LOC392352 - +392358 RPS6P13 HGNC:HGNC:35772 +392360 CTSL3P HGNC:HGNC:33132|Ensembl:ENSG00000188029 +392364 LOC392364 - +392368 BEND3P2 HGNC:HGNC:45015 +392371 KRT18P13 HGNC:HGNC:6432 +392374 GAPDHP26 HGNC:HGNC:37778 +392375 OR13D2P HGNC:HGNC:15105 +392376 OR13C2 HGNC:HGNC:14701|Ensembl:ENSG00000276119|Vega:OTTHUMG00000020415 +392377 OR13C1P HGNC:HGNC:14699 +392382 RPL31P43 HGNC:HGNC:36512 +392387 AHCYP2 HGNC:HGNC:44994 +392390 OR1L6 HGNC:HGNC:8218|Ensembl:ENSG00000171459|Vega:OTTHUMG00000020621 +392391 OR5C1 HGNC:HGNC:8331|Ensembl:ENSG00000148215|Vega:OTTHUMG00000020622 +392392 OR1K1 HGNC:HGNC:8212|Ensembl:ENSG00000165204|Vega:OTTHUMG00000020625 +392399 LCN9 MIM:612903|HGNC:HGNC:17442|Ensembl:ENSG00000148386|Vega:OTTHUMG00000020916 +392424 RPS5P8 HGNC:HGNC:36531 +392425 RPS27AP17 HGNC:HGNC:36877 +392426 LOC392426 - +392428 NPM1P9 HGNC:HGNC:7929 +392433 MAGEB6P1 HGNC:HGNC:28824 +392435 LOC392435 - +392436 LOC392436 - +392437 FTLP2 HGNC:HGNC:4001 +392439 LOC392439 - +392440 LOC392440 - +392442 LOC392442 - +392447 RPL32P36 HGNC:HGNC:36613 +392451 RPL19P20 HGNC:HGNC:35713 +392452 LOC392452 - +392454 PCNAP3 HGNC:HGNC:43736 +392456 LOC392456 - +392459 CXXC1P1 HGNC:HGNC:27864|Ensembl:ENSG00000187893 +392465 GLOD5 HGNC:HGNC:33358|Ensembl:ENSG00000171433|Vega:OTTHUMG00000024125 +392477 LOC392477 - +392479 KRT8P17 HGNC:HGNC:33369 +392485 LOC392485 - +392486 GPR165P HGNC:HGNC:21462 +392489 LOC392489 - +392490 FLJ44635 - +392497 RPS6P26 HGNC:HGNC:36713 +392501 RPL26P36 HGNC:HGNC:36685 +392505 RPL6P29 HGNC:HGNC:36382 +392508 LOC392508 - +392509 ARL13A HGNC:HGNC:31709|Ensembl:ENSG00000174225|Vega:OTTHUMG00000022013 +392510 YWHAQP8 HGNC:HGNC:37687 +392516 KRT18P49 HGNC:HGNC:33419 +392517 NCBP2L HGNC:HGNC:31795|Vega:OTTHUMG00000022169 +392520 RPS5P7 HGNC:HGNC:36881 +392522 RPL18AP15 HGNC:HGNC:36010 +392525 AKR1B1P8 HGNC:HGNC:33496 +392529 LOC392529 - +392536 LOC392536 - +392538 LOC392538 - +392539 LOC392539 - +392540 OR11N1P HGNC:HGNC:19582 +392543 LOC392543 - +392545 HMGB3P31 HGNC:HGNC:39334 +392547 CROCCP1 HGNC:HGNC:33602 +392552 KRT8P6 HGNC:HGNC:33360 +392555 LOC392555 - +392557 RPL19P21 HGNC:HGNC:35868 +392561 OR3B1P HGNC:HGNC:14839 +392597 TRAPPC2P7 HGNC:HGNC:10716 +392603 ZNF736P2Y HGNC:HGNC:37727 +392617 ELFN1 MIM:614964|HGNC:HGNC:33154|Ensembl:ENSG00000225968|Vega:OTTHUMG00000151495 +392636 AGMO MIM:613738|HGNC:HGNC:33784|Ensembl:ENSG00000187546|Vega:OTTHUMG00000152387 +392713 PMS2P12 HGNC:HGNC:13641 +392748 RPS27P17 HGNC:HGNC:36291 +392752 OR7E7P HGNC:HGNC:8457 +392781 RPS2P31 HGNC:HGNC:36965 +392787 LOC392787 - +392843 IQCA1L HGNC:HGNC:22831|Ensembl:ENSG00000278685|Vega:OTTHUMG00000156140 +392862 GRID2IP MIM:610639|HGNC:HGNC:18464|Ensembl:ENSG00000215045|Vega:OTTHUMG00000155531 +392872 RPL12P10 HGNC:HGNC:22583 +392979 RPL18P4 HGNC:HGNC:36144 +393046 OR2A5 HGNC:HGNC:8232|Ensembl:ENSG00000221836|Vega:OTTHUMG00000158006 +393093 MYP4 HGNC:HGNC:32549 +394214 COL11A2P1 HGNC:HGNC:13947 +394217 FGF7P2 HGNC:HGNC:17193 +394254 GPR89P HGNC:HGNC:13951 +394255 RPS10P1 HGNC:HGNC:13981 +394261 KLHL30-AS1 HGNC:HGNC:31018 +394263 MUC21 MIM:616991|HGNC:HGNC:21661|Ensembl:ENSG00000204544|Vega:OTTHUMG00000031216 +394269 BRCA1P1 HGNC:HGNC:28470 +399473 SPRED3 MIM:609293|HGNC:HGNC:31041|Ensembl:ENSG00000188766|Vega:OTTHUMG00000182082 +399474 TMEM200B HGNC:HGNC:33785|Ensembl:ENSG00000253304|Vega:OTTHUMG00000003658 +399495 SLC2A3P4 HGNC:HGNC:31076 +399496 SLC2AXP1 HGNC:HGNC:31077 +399511 TCEA1P2 HGNC:HGNC:29891 +399512 SLC25A35 MIM:610818|HGNC:HGNC:31921|Ensembl:ENSG00000125434|Vega:OTTHUMG00000178480 +399516 OTSC7 MIM:611572|HGNC:HGNC:31084 +399520 TIMM8AP1 HGNC:HGNC:17802 +399564 GLC1H MIM:611276|HGNC:HGNC:23256 +399565 GLC3C MIM:613085|HGNC:HGNC:30028 +399656 FAM32BP HGNC:HGNC:30945 +399664 MEX3D MIM:611009|HGNC:HGNC:16734|Ensembl:ENSG00000181588|Vega:OTTHUMG00000150369 +399665 FAM102A MIM:610891|HGNC:HGNC:31419|Ensembl:ENSG00000167106|Vega:OTTHUMG00000020720 +399666 ARL2BPP1 HGNC:HGNC:17742 +399668 SMIM10L2A HGNC:HGNC:34499|Ensembl:ENSG00000178947|Vega:OTTHUMG00000022479 +399669 ZNF321P HGNC:HGNC:13827|Ensembl:ENSG00000213801 +399670 RPL13AP17 HGNC:HGNC:36167|Ensembl:ENSG00000231322 +399671 HEATR4 HGNC:HGNC:16761|Ensembl:ENSG00000187105|Vega:OTTHUMG00000171602 +399687 MYO18A MIM:610067|HGNC:HGNC:31104|Ensembl:ENSG00000196535|Vega:OTTHUMG00000166360 +399693 CCDC187 HGNC:HGNC:30942|Ensembl:ENSG00000260220|Vega:OTTHUMG00000188591 +399694 SHC4 MIM:617372|HGNC:HGNC:16743|Ensembl:ENSG00000185634|Vega:OTTHUMG00000131513 +399697 CTXN2 HGNC:HGNC:31109|Ensembl:ENSG00000233932|Vega:OTTHUMG00000172152 +399706 LINC00200 HGNC:HGNC:30974|Ensembl:ENSG00000229205 +399708 LINC00701 HGNC:HGNC:44674 +399715 LOC399715 Ensembl:ENSG00000215244 +399716 LOC399716 - +399717 GATA3-AS1 HGNC:HGNC:33786|Ensembl:ENSG00000197308 +399726 CASC10 HGNC:HGNC:31448|Ensembl:ENSG00000204682|Vega:OTTHUMG00000017795 +399744 LINC00999 HGNC:HGNC:38537 +399746 ACTR3BP5 HGNC:HGNC:38682 +399748 CAP1P2 HGNC:HGNC:31970 +399761 BMS1P5 HGNC:HGNC:23653|Ensembl:ENSG00000204177 +399774 THAP12P3 HGNC:HGNC:39567 +399783 LOC399783 - +399804 NPM1P25 HGNC:HGNC:45204 +399806 LBX1-AS1 HGNC:HGNC:48678 +399814 C10orf120 HGNC:HGNC:25707|Ensembl:ENSG00000183559|Vega:OTTHUMG00000019187 +399815 LOC399815 - +399818 EEF1AKMT2 HGNC:HGNC:33787|Ensembl:ENSG00000203791|Vega:OTTHUMG00000019217 +399821 FLJ37035 Ensembl:ENSG00000224023 +399823 FOXI2 MIM:617202|HGNC:HGNC:32448|Ensembl:ENSG00000186766|Vega:OTTHUMG00000019250 +399827 LINC01164 HGNC:HGNC:49533|Ensembl:ENSG00000189275 +399829 LINC01168 HGNC:HGNC:49537|Ensembl:ENSG00000240707 +399833 SPRNP1 HGNC:HGNC:37819 +399839 DUX4L11 HGNC:HGNC:38687 +399844 LINC01002 HGNC:HGNC:38538 +399857 OR7E117P HGNC:HGNC:15303 +399876 NAV2-AS4 HGNC:HGNC:40741|Ensembl:ENSG00000254622 +399881 HNRNPKP3 HGNC:HGNC:42376|Ensembl:ENSG00000251557 +399886 LOC399886 Ensembl:ENSG00000255267 +399888 FAM180B HGNC:HGNC:34451|Ensembl:ENSG00000196666|Vega:OTTHUMG00000167871 +399900 LOC399900 Ensembl:ENSG00000279491 +399909 PCNX3 HGNC:HGNC:18760|Ensembl:ENSG00000197136|Vega:OTTHUMG00000166539 +399923 FLJ42102 Ensembl:ENSG00000172900 +399937 TRIM51BP HGNC:HGNC:37145 +399939 TRIM49D1 HGNC:HGNC:43973|Ensembl:ENSG00000223417|Vega:OTTHUMG00000167643 +399940 TRIM51EP HGNC:HGNC:43970 +399942 TUBAP2 HGNC:HGNC:14531 +399947 C11orf87 HGNC:HGNC:33788|Ensembl:ENSG00000185742|Vega:OTTHUMG00000166559 +399948 COLCA1 MIM:615693|HGNC:HGNC:33789 +399949 C11orf88 HGNC:HGNC:25061|Ensembl:ENSG00000183644|Vega:OTTHUMG00000166720 +399950 ST13P10 HGNC:HGNC:38745 +399959 MIR100HG MIM:615965|HGNC:HGNC:39522 +399965 KRT18P59 HGNC:HGNC:48886 +399967 PATE2 HGNC:HGNC:32249|Ensembl:ENSG00000196844|Vega:OTTHUMG00000165856 +399968 PATE4 HGNC:HGNC:35427|Ensembl:ENSG00000237353|Vega:OTTHUMG00000165235 +399972 GSEC HGNC:HGNC:48645 +399975 LOC399975 - +399979 SNX19 HGNC:HGNC:21532|Ensembl:ENSG00000120451|Vega:OTTHUMG00000165663 +399988 HSPA8P5 HGNC:HGNC:44920 +399994 HADHAP2 HGNC:HGNC:38585 +400002 CLEC12A-AS1 HGNC:HGNC:53407|Ensembl:ENSG00000231560 +400011 SUPT16HP1 HGNC:HGNC:31388 +400013 TCP1P3 HGNC:HGNC:21630 +400026 LOC400026 - +400027 LINC00938 HGNC:HGNC:48630 +400036 LOC400036 - +400043 LINC02381 HGNC:HGNC:53304|Ensembl:ENSG00000250742 +400046 LINC02389 HGNC:HGNC:53316|Ensembl:ENSG00000255693 +400055 RPL26P32 HGNC:HGNC:36448 +400058 MKRN9P HGNC:HGNC:7116 +400061 LOC400061 - +400064 RPS4XP1 HGNC:HGNC:32444 +400073 C12orf76 HGNC:HGNC:33790|Ensembl:ENSG00000174456|Vega:OTTHUMG00000169315 +400084 LINC00939 HGNC:HGNC:48631|Ensembl:ENSG00000249267 +400087 LINC02393 HGNC:HGNC:53320|Ensembl:ENSG00000256597 +400094 SNX19P2 HGNC:HGNC:38115 +400110 ANKRD20A19P HGNC:HGNC:42737 +400120 SERTM1 HGNC:HGNC:33792|Ensembl:ENSG00000180440|Vega:OTTHUMG00000016735 +400121 LINC00547 HGNC:HGNC:43682|Ensembl:ENSG00000275226 +400123 LINC00548 HGNC:HGNC:43683|Ensembl:ENSG00000215483 +400126 DGKZP1 HGNC:HGNC:39263 +400128 TUSC8 HGNC:HGNC:49111|Ensembl:ENSG00000237361 +400129 SMARCE1P5 HGNC:HGNC:39734 +400141 RPSAP53 HGNC:HGNC:36641 +400156 RPS26P47 HGNC:HGNC:36368 +400165 ATP11AUN HGNC:HGNC:33793 +400174 LOC400174 - +400206 DPPA3P2 HGNC:HGNC:20417 +400208 LINC00517 HGNC:HGNC:19831|Ensembl:ENSG00000259091 +400209 YTHDF2P1 HGNC:HGNC:19865 +400212 LOC400212 - +400221 FLJ22447 Ensembl:ENSG00000232774 +400224 PLEKHD1 HGNC:HGNC:20148|Ensembl:ENSG00000175985|Vega:OTTHUMG00000171233 +400236 FOXN3-AS1 HGNC:HGNC:44290|Ensembl:ENSG00000258920 +400238 LINC00642 HGNC:HGNC:44293|Ensembl:ENSG00000233208 +400242 DICER1-AS1 HGNC:HGNC:43017|Ensembl:ENSG00000235706 +400258 C14orf180 HGNC:HGNC:33795|Ensembl:ENSG00000184601|Vega:OTTHUMG00000029806 +400322 HERC2P2 HGNC:HGNC:4870|Ensembl:ENSG00000276550 +400347 LOC400347 - +400359 C15orf53 HGNC:HGNC:33796|Ensembl:ENSG00000175779|Vega:OTTHUMG00000129841 +400360 C15orf54 HGNC:HGNC:33797 +400385 RPL5P3 HGNC:HGNC:31034 +400389 RPL12P35 HGNC:HGNC:35969 +400403 DNM1P9 HGNC:HGNC:21126 +400406 ADAMTS7P3 HGNC:HGNC:49409 +400410 ST20 HGNC:HGNC:33520|Ensembl:ENSG00000180953|Vega:OTTHUMG00000172078 +400433 DNM1P40 HGNC:HGNC:35190 +400446 LOC400446 - +400451 FAM174B HGNC:HGNC:34339|Ensembl:ENSG00000185442|Vega:OTTHUMG00000171744 +400456 LINC01197 HGNC:HGNC:49597|Ensembl:ENSG00000248441 +400464 LOC400464 Ensembl:ENSG00000259363 +400499 LOC400499 Ensembl:ENSG00000188897|Vega:OTTHUMG00000178167 +400500 BCAR4 MIM:613746|HGNC:HGNC:22170|Ensembl:ENSG00000262117 +400506 KNOP1 HGNC:HGNC:34404|Ensembl:ENSG00000103550|Vega:OTTHUMG00000177249 +400508 CRYM-AS1 HGNC:HGNC:34405 +400511 LINC01567 HGNC:HGNC:51367|Ensembl:ENSG00000224310 +400512 FLJ21408 Ensembl:ENSG00000245888 +400533 LINC02167 HGNC:HGNC:53028|Ensembl:ENSG00000261122 +400541 LOC400541 Ensembl:ENSG00000247228 +400548 LINC02139 HGNC:HGNC:52999|Ensembl:ENSG00000278214 +400550 FENDRR MIM:614975|HGNC:HGNC:43894|Ensembl:ENSG00000268388 +400553 LOC400553 Ensembl:ENSG00000205037 +400555 ZC3H18-AS1 HGNC:HGNC:33799 +400558 LINC02138 HGNC:HGNC:52998|Ensembl:ENSG00000205015 +400566 C17orf97 HGNC:HGNC:33800|Ensembl:ENSG00000187624|Vega:OTTHUMG00000132479 +400568 LINC01996 HGNC:HGNC:52830|Ensembl:ENSG00000261863 +400569 MED11 MIM:612383|HGNC:HGNC:32687|Ensembl:ENSG00000161920|Vega:OTTHUMG00000177896 +400578 KRT16P2 HGNC:HGNC:37807 +400579 LINC02076 HGNC:HGNC:52924|Ensembl:ENSG00000220161 +400581 GRAPL HGNC:HGNC:37240|Ensembl:ENSG00000189152|Vega:OTTHUMG00000059435 +400591 C17orf102 HGNC:HGNC:34412 +400604 TOB1-AS1 HGNC:HGNC:44340|Ensembl:ENSG00000229980 +400609 TBC1D3P1 HGNC:HGNC:27445 +400612 PRR29-AS1 HGNC:HGNC:51822|Ensembl:ENSG00000264954 +400617 KCNJ2-AS1 HGNC:HGNC:43720|Ensembl:ENSG00000267365 +400618 SOX9-AS1 HGNC:HGNC:49321|Ensembl:ENSG00000234899 +400619 LINC00511 HGNC:HGNC:43564|Ensembl:ENSG00000227036 +400620 LINC02092 HGNC:HGNC:52943|Ensembl:ENSG00000234721 +400622 LOC400622 - +400624 LINC01973 HGNC:HGNC:52800|Ensembl:ENSG00000204283 +400627 LOC400627 - +400629 TEX19 MIM:615647|HGNC:HGNC:33802|Ensembl:ENSG00000182459|Vega:OTTHUMG00000132857 +400643 LINC00668 HGNC:HGNC:44328|Ensembl:ENSG00000265933 +400644 LINC01443 HGNC:HGNC:50768|Ensembl:ENSG00000266554 +400645 RBM22P1 HGNC:HGNC:31466 +400650 TPMTP1 HGNC:HGNC:17490 +400652 RPS3AP49 HGNC:HGNC:36810 +400654 LINC01538 HGNC:HGNC:51306|Ensembl:ENSG00000266952 +400655 LOC400655 Ensembl:ENSG00000263711 +400657 LINC00909 HGNC:HGNC:44331|Ensembl:ENSG00000264247 +400658 C18orf65 HGNC:HGNC:51248 +400660 LINC00683 HGNC:HGNC:44467|Ensembl:ENSG00000266256 +400661 LINC01879 HGNC:HGNC:52698|Ensembl:ENSG00000276397 +400668 PRSS57 HGNC:HGNC:31397|Ensembl:ENSG00000185198|Vega:OTTHUMG00000180662 +400673 VMAC MIM:617204|HGNC:HGNC:33803|Ensembl:ENSG00000187650|Vega:OTTHUMG00000180618 +400680 LINC00664 HGNC:HGNC:44319|Ensembl:ENSG00000268658 +400682 LOC400682 - +400684 LOC400684 Ensembl:ENSG00000267213 +400685 LINC01801 HGNC:HGNC:52592|Ensembl:ENSG00000267767 +400696 LGALS17A Ensembl:ENSG00000226025 +400706 LOC400706 Ensembl:ENSG00000204869 +400709 SIGLEC16 HGNC:HGNC:24851|Ensembl:ENSG00000161643|Vega:OTTHUMG00000183074 +400710 LOC400710 Ensembl:ENSG00000204666 +400713 ZNF880 HGNC:HGNC:37249|Ensembl:ENSG00000221923|Vega:OTTHUMG00000167972 +400720 ZNF772 HGNC:HGNC:33106|Ensembl:ENSG00000197128|Vega:OTTHUMG00000168007 +400728 FAM87B HGNC:HGNC:32236|Ensembl:ENSG00000177757 +400735 PRAMEF4 HGNC:HGNC:31971|Ensembl:ENSG00000243073|Vega:OTTHUMG00000001987 +400736 PRAMEF13 HGNC:HGNC:13262|Ensembl:ENSG00000279169 +400743 LOC400743 - +400745 SH2D5 HGNC:HGNC:28819|Ensembl:ENSG00000189410|Vega:OTTHUMG00000002620 +400746 NCMAP HGNC:HGNC:29332|Ensembl:ENSG00000184454|Vega:OTTHUMG00000003317 +400748 LOC400748 - +400750 LOC400750 - +400752 LINC01144 HGNC:HGNC:49460|Ensembl:ENSG00000281912 +400757 C1orf141 HGNC:HGNC:32044|Ensembl:ENSG00000203963|Vega:OTTHUMG00000009406 +400759 GBP1P1 HGNC:HGNC:39561|Ensembl:ENSG00000225492 +400761 FLJ27354 Ensembl:ENSG00000231999 +400765 MIR137HG HGNC:HGNC:42871|Ensembl:ENSG00000225206 +400769 HNRNPA1P43 HGNC:HGNC:48772 +400793 C1orf226 HGNC:HGNC:34351|Ensembl:ENSG00000239887|Vega:OTTHUMG00000031376 +400794 LOC400794 Ensembl:ENSG00000237463 +400797 CLEC20A HGNC:HGNC:34521|Ensembl:ENSG00000188585|Vega:OTTHUMG00000035021 +400798 C1orf220 HGNC:HGNC:33805|Ensembl:ENSG00000213057 +400799 LINC01344 HGNC:HGNC:50554|Ensembl:ENSG00000228918 +400800 LOC400800 - +400804 C1orf140 Ensembl:ENSG00000234754 +400812 FLJ39095 - +400818 NBPF9 MIM:613999|HGNC:HGNC:31991|Ensembl:ENSG00000269713|Vega:OTTHUMG00000013845 +400823 FAM177B HGNC:HGNC:34395|Ensembl:ENSG00000197520|Vega:OTTHUMG00000037766 +400830 DEFB132 HGNC:HGNC:33806|Ensembl:ENSG00000186458|Vega:OTTHUMG00000043061 +400831 C20orf202 HGNC:HGNC:37254|Ensembl:ENSG00000215595|Vega:OTTHUMG00000129375 +400836 SDAD1P2 HGNC:HGNC:31404 +400839 LINC01721 HGNC:HGNC:52508|Ensembl:ENSG00000230133 +400841 LINC01597 HGNC:HGNC:51594 +400866 LINC00114 MIM:611723|HGNC:HGNC:1265|Ensembl:ENSG00000223806 +400867 LOC400867 - +400870 LOC400870 - +400891 LRRC74B HGNC:HGNC:34301|Ensembl:ENSG00000187905|Vega:OTTHUMG00000150897 +400892 BCRP2 HGNC:HGNC:1015 +400916 CHCHD10 MIM:615903|HGNC:HGNC:15559|Ensembl:ENSG00000250479|Vega:OTTHUMG00000150736 +400927 LOC400927 - +400931 MIRLET7BHG HGNC:HGNC:37189|Ensembl:ENSG00000197182 +400932 LINC00898 HGNC:HGNC:48581|Ensembl:ENSG00000205634 +400935 IL17REL MIM:613414|HGNC:HGNC:33808|Ensembl:ENSG00000188263|Vega:OTTHUMG00000150242 +400940 LOC400940 - +400941 LINC00487 HGNC:HGNC:42947|Ensembl:ENSG00000205837 +400945 LINC01376 HGNC:HGNC:50637|Ensembl:ENSG00000236204 +400946 LINC00954 HGNC:HGNC:48668|Ensembl:ENSG00000228784 +400949 FKSG49 - +400950 C2orf91 HGNC:HGNC:42966|Ensembl:ENSG00000205086|Vega:OTTHUMG00000152307 +400952 LINC01121 HGNC:HGNC:49266|Ensembl:ENSG00000205054 +400954 EML6 HGNC:HGNC:35412|Ensembl:ENSG00000214595|Vega:OTTHUMG00000152035 +400955 LINC01122 HGNC:HGNC:49267|Ensembl:ENSG00000233723 +400957 LINC01185 HGNC:HGNC:49572|Ensembl:ENSG00000228414 +400958 LINC02245 HGNC:HGNC:53134 +400960 PCBP1-AS1 HGNC:HGNC:42948|Ensembl:ENSG00000179818 +400961 PAIP2B MIM:611018|HGNC:HGNC:29200|Ensembl:ENSG00000124374|Vega:OTTHUMG00000153284 +400963 RPS2P17 HGNC:HGNC:35764 +400966 RGPD1 MIM:612704|HGNC:HGNC:32414|Ensembl:ENSG00000187627|Vega:OTTHUMG00000153248 +400984 OR7E102P HGNC:HGNC:15043 +400986 ANKRD36C HGNC:HGNC:32946|Ensembl:ENSG00000174501|Vega:OTTHUMG00000155211 +400997 ACOXL-AS1 HGNC:HGNC:41112|Ensembl:ENSG00000204581 +400999 FLJ42351 - +401002 LOC401002 - +401007 NF1P8 HGNC:HGNC:7767 +401010 NOC2LP2 HGNC:HGNC:52286 +401014 TEX41 HGNC:HGNC:48667|Ensembl:ENSG00000226674 +401018 CTAGE14P HGNC:HGNC:37299 +401019 RPS15P4 HGNC:HGNC:35712 +401021 LOC401021 - +401022 HAGLR HGNC:HGNC:43755|Ensembl:ENSG00000224189 +401024 FSIP2 MIM:615796|HGNC:HGNC:21675|Ensembl:ENSG00000188738|Vega:OTTHUMG00000153874 +401027 C2orf66 HGNC:HGNC:33809|Ensembl:ENSG00000187944|Vega:OTTHUMG00000132742 +401036 ASB18 HGNC:HGNC:19770|Ensembl:ENSG00000182177|Vega:OTTHUMG00000153086 +401039 LINC01940 HGNC:HGNC:52763|Ensembl:ENSG00000227744 +401040 LOC401040 - +401052 LOC401052 - +401067 IQCF3 HGNC:HGNC:31816|Ensembl:ENSG00000229972|Vega:OTTHUMG00000156910 +401074 LINC00960 HGNC:HGNC:48710|Ensembl:ENSG00000242516 +401076 CAP1P1 HGNC:HGNC:31134 +401081 C3orf85 HGNC:HGNC:53432|Ensembl:ENSG00000241224 +401082 LINC01205 HGNC:HGNC:49636|Ensembl:ENSG00000228980 +401089 FOXL2NB HGNC:HGNC:34428|Ensembl:ENSG00000206262|Vega:OTTHUMG00000159886 +401093 MBNL1-AS1 HGNC:HGNC:44584|Ensembl:ENSG00000229619 +401097 C3orf80 HGNC:HGNC:40048|Ensembl:ENSG00000180044 +401103 LINC01994 HGNC:HGNC:52827|Ensembl:ENSG00000241098 +401105 FLJ42393 Ensembl:ENSG00000279891 +401106 LINC00884 HGNC:HGNC:48570 +401109 LINC00885 HGNC:HGNC:48571|Ensembl:ENSG00000224652 +401115 C4orf48 MIM:614690|HGNC:HGNC:34437|Ensembl:ENSG00000243449|Vega:OTTHUMG00000154503 +401124 DTHD1 MIM:616979|HGNC:HGNC:37261|Ensembl:ENSG00000197057|Vega:OTTHUMG00000160371 +401127 LOC401127 Ensembl:ENSG00000224097 +401131 LOC401131 - +401134 LINC02232 HGNC:HGNC:53103|Ensembl:ENSG00000250125 +401135 SYT14P1 MIM:610892|HGNC:HGNC:33429 +401136 TMPRSS11BNL HGNC:HGNC:37262|Ensembl:ENSG00000250026 +401137 PRR27 HGNC:HGNC:33193|Ensembl:ENSG00000187533|Vega:OTTHUMG00000129402 +401138 AMTN MIM:610912|HGNC:HGNC:33188|Ensembl:ENSG00000187689|Vega:OTTHUMG00000129906 +401145 CCSER1 HGNC:HGNC:29349|Ensembl:ENSG00000184305|Vega:OTTHUMG00000160950 +401149 LINC01061 HGNC:HGNC:49084 +401152 C4orf3 HGNC:HGNC:19225|Ensembl:ENSG00000164096|Vega:OTTHUMG00000161333 +401164 LINC01060 HGNC:HGNC:49081|Ensembl:ENSG00000249378 +401172 LINC02145 HGNC:HGNC:53005|Ensembl:ENSG00000250490 +401176 LOC401176 - +401177 LINC02111 HGNC:HGNC:52966|Ensembl:ENSG00000250822 +401190 RGS7BP MIM:610890|HGNC:HGNC:23271|Ensembl:ENSG00000186479|Vega:OTTHUMG00000162293 +401191 LOC401191 - +401206 RPS25P6 HGNC:HGNC:35532 +401207 C5orf63 HGNC:HGNC:40051|Ensembl:ENSG00000164241|Vega:OTTHUMG00000163037 +401218 LOC401218 - +401232 LINC01011 HGNC:HGNC:33812 +401233 HTATSF1P2 HGNC:HGNC:38586 +401236 STMND1 HGNC:HGNC:44668|Ensembl:ENSG00000230873 +401237 CASC15 MIM:616610|HGNC:HGNC:28245|Ensembl:ENSG00000272168 +401242 LINC01623 HGNC:HGNC:52050|Ensembl:ENSG00000225595 +401247 LINC00243 HGNC:HGNC:30956|Ensembl:ENSG00000214894 +401250 MCCD1 MIM:609624|HGNC:HGNC:20668|Ensembl:ENSG00000204511|Vega:OTTHUMG00000134292 +401251 SAPCD1 HGNC:HGNC:13938|Ensembl:ENSG00000228727|Vega:OTTHUMG00000031131 +401253 LINC00336 HGNC:HGNC:33813|Ensembl:ENSG00000197251 +401258 RAB44 HGNC:HGNC:21068|Ensembl:ENSG00000255587|Vega:OTTHUMG00000016308 +401260 LINC00951 HGNC:HGNC:48662 +401261 LOC401261 - +401262 CRIP3 HGNC:HGNC:17751|Ensembl:ENSG00000146215|Vega:OTTHUMG00000014727 +401264 TRAM2-AS1 HGNC:HGNC:48663|Ensembl:ENSG00000225791 +401265 KLHL31 MIM:610749|HGNC:HGNC:21353|Ensembl:ENSG00000124743|Vega:OTTHUMG00000014882 +401282 DKFZp451B082 - +401285 TCP10L2 HGNC:HGNC:21254|Ensembl:ENSG00000166984|Vega:OTTHUMG00000016014 +401286 LINC02538 HGNC:HGNC:53571|Ensembl:ENSG00000272549 +401288 LINC00242 HGNC:HGNC:21249|Ensembl:ENSG00000229214 +401289 LINC01624 HGNC:HGNC:52051 +401296 LOC401296 - +401303 ZNF815P HGNC:HGNC:22029 +401312 LOC401312 Ensembl:ENSG00000238033 +401316 EIF4HP1 HGNC:HGNC:49035 +401320 LOC401320 - +401321 LINC00997 HGNC:HGNC:48952 +401324 LOC401324 - +401331 RASA4CP HGNC:HGNC:44185 +401335 C7orf65 HGNC:HGNC:34432 +401337 LINC01446 HGNC:HGNC:50773|Ensembl:ENSG00000205628 +401357 LOC401357 - +401375 GTF2IRD2P1 HGNC:HGNC:33127 +401387 LRRD1 HGNC:HGNC:34300|Ensembl:ENSG00000240720|Vega:OTTHUMG00000155861 +401393 AZGP1P2 HGNC:HGNC:912 +401397 SMIM30 HGNC:HGNC:48953|Ensembl:ENSG00000214194|Vega:OTTHUMG00000154780 +401398 POT1-AS1 HGNC:HGNC:49459|Ensembl:ENSG00000224897 +401399 PRRT4 HGNC:HGNC:37280|Ensembl:ENSG00000224940|Vega:OTTHUMG00000157714 +401409 RAB19 HGNC:HGNC:19982|Ensembl:ENSG00000146955|Vega:OTTHUMG00000157410 +401427 OR2A7 HGNC:HGNC:8234|Ensembl:ENSG00000243896|Vega:OTTHUMG00000158002 +401428 OR2A20P HGNC:HGNC:15413|Ensembl:ENSG00000170356 +401431 ATP6V0E2-AS1 HGNC:HGNC:44180|Ensembl:ENSG00000204934 +401442 LOC401442 Ensembl:ENSG00000282375 +401447 USP17L1 HGNC:HGNC:37182|Ensembl:ENSG00000230549|Vega:OTTHUMG00000150578 +401450 OR7E96P HGNC:HGNC:14815 +401463 LOC401463 Ensembl:ENSG00000254102 +401466 C8orf59 HGNC:HGNC:32235|Ensembl:ENSG00000176731|Vega:OTTHUMG00000164787 +401470 RPS26P10 HGNC:HGNC:32201 +401471 LOC401471 - +401472 LOC401472 - +401474 SAMD12 HGNC:HGNC:31750|Ensembl:ENSG00000177570|Vega:OTTHUMG00000059817 +401475 SRRM1P1 HGNC:HGNC:31861 +401478 LOC401478 - +401491 VLDLR-AS1 HGNC:HGNC:49621|Ensembl:ENSG00000236404 +401492 LINC01235 HGNC:HGNC:49769|Ensembl:ENSG00000270547 +401494 HACD4 MIM:615941|HGNC:HGNC:20920|Ensembl:ENSG00000188921|Vega:OTTHUMG00000021016 +401497 LINC01242 HGNC:HGNC:49810 +401498 TMEM215 HGNC:HGNC:33816|Ensembl:ENSG00000188133|Vega:OTTHUMG00000129521 +401505 TOMM5 MIM:616169|HGNC:HGNC:31369|Ensembl:ENSG00000175768|Vega:OTTHUMG00000019923 +401507 FAM74A1 HGNC:HGNC:32029|Ensembl:ENSG00000215112 +401508 FAM74A4 HGNC:HGNC:32032|Ensembl:ENSG00000274583 +401509 ZNF658B HGNC:HGNC:32033 +401525 CDK2AP2P3 HGNC:HGNC:38494 +401533 DDX10P2 HGNC:HGNC:44961 +401535 C9orf170 HGNC:HGNC:33817 +401537 RPSAP49 HGNC:HGNC:35660 +401540 OR7E109P HGNC:HGNC:15118 +401541 CENPP MIM:611505|HGNC:HGNC:32933|Ensembl:ENSG00000188312|Vega:OTTHUMG00000020228 +401546 C9orf152 HGNC:HGNC:31455|Ensembl:ENSG00000188959|Vega:OTTHUMG00000020478 +401548 SNX30 HGNC:HGNC:23685|Ensembl:ENSG00000148158|Vega:OTTHUMG00000020512 +401551 WDR38 HGNC:HGNC:23745|Ensembl:ENSG00000136918|Vega:OTTHUMG00000020664 +401554 LOC401554 Ensembl:ENSG00000196979 +401557 LOC401557 - +401561 LINC01451 HGNC:HGNC:48599|Ensembl:ENSG00000279141 +401562 LCNL1 HGNC:HGNC:34436|Ensembl:ENSG00000214402|Vega:OTTHUMG00000159546 +401563 C9orf139 HGNC:HGNC:31426 +401565 FAM166A HGNC:HGNC:33818|Ensembl:ENSG00000188163|Vega:OTTHUMG00000159545 +401577 CD99P1 HGNC:HGNC:7083|Ensembl:ENSG00000223773 +401585 LOC401585 Ensembl:ENSG00000231566 +401588 ZNF674-AS1 HGNC:HGNC:44266|Ensembl:ENSG00000230844 +401589 LOC401589 - +401602 LOC401602 - +401612 SLC25A53 MIM:300941|HGNC:HGNC:31894|Ensembl:ENSG00000269743|Vega:OTTHUMG00000022124 +401613 LINC00890 HGNC:HGNC:48576|Ensembl:ENSG00000260802|Vega:OTTHUMG00000173027 +401629 FAM224B HGNC:HGNC:37737 +401630 FAM224A HGNC:HGNC:37736 +401634 GOLGA2P3Y HGNC:HGNC:32426 +401637 OR7E26P HGNC:HGNC:8398 +401638 RPSAP10 HGNC:HGNC:31460 +401640 RPL7AP53 HGNC:HGNC:36392 +401646 GNAI2P2 HGNC:HGNC:45110 +401647 GOLGA7B MIM:614189|HGNC:HGNC:31668|Ensembl:ENSG00000155265|Vega:OTTHUMG00000018869 +401648 ST13P13 HGNC:HGNC:38788 +401661 OR51C1P HGNC:HGNC:15191 +401662 OR51A8P HGNC:HGNC:15189 +401663 OR51H1 HGNC:HGNC:14833|Vega:OTTHUMG00000066512 +401664 OR51H2P HGNC:HGNC:15199 +401665 OR51T1 HGNC:HGNC:15205|Ensembl:ENSG00000176900|Vega:OTTHUMG00000066507 +401666 OR51A4 HGNC:HGNC:14795|Ensembl:ENSG00000205497|Vega:OTTHUMG00000066614 +401667 OR51A2 HGNC:HGNC:14764|Ensembl:ENSG00000205496|Vega:OTTHUMG00000066602 +401675 OR56B3P HGNC:HGNC:15247 +401677 LOC401677 - +401679 LOC401679 - +401687 OR5J1P HGNC:HGNC:8348 +401692 OR5B1P HGNC:HGNC:8322 +401696 OR4D8P HGNC:HGNC:15177 +401703 LOC401703 - +401708 GLULP3 HGNC:HGNC:4344 +401717 EEF1A1P17 HGNC:HGNC:37890 +401718 OR5BK1P HGNC:HGNC:14817 +401720 FIGNL2 HGNC:HGNC:13287|Ensembl:ENSG00000261308 +401725 RPL6P25 HGNC:HGNC:36840 +401730 IPMKP1 HGNC:HGNC:39354 +401742 OR11K2P HGNC:HGNC:19635 +401744 SMARCE1P3 HGNC:HGNC:39733 +401767 LOC401767 - +401770 LOC401770 - +401777 LOC401777 - +401805 LOC401805 - +401817 RPS10P22 HGNC:HGNC:35814 +401822 FDPSP9 HGNC:HGNC:39086 +401825 NIFKP1 HGNC:HGNC:44949 +401827 MSLNL HGNC:HGNC:14170 +401863 RPL10AP12 HGNC:HGNC:36108 +401864 LOC401864 - +401865 RPL7AP63 HGNC:HGNC:35504 +401875 LOC401875 - +401895 RPS15P9 HGNC:HGNC:36440 +401898 ZNF833P HGNC:HGNC:33819 +401903 OR10B1P HGNC:HGNC:8163 +401904 RPL23AP2 HGNC:HGNC:10319 +401911 RPL29P33 HGNC:HGNC:36923 +401913 LOC401913 - +401914 CTBP2P7 HGNC:HGNC:45199 +401934 RNF223 HGNC:HGNC:40020|Ensembl:ENSG00000237330|Vega:OTTHUMG00000185582 +401944 LDLRAD2 HGNC:HGNC:32071|Ensembl:ENSG00000187942|Vega:OTTHUMG00000002675 +401957 LOC401957 - +401959 VDAC2P3 HGNC:HGNC:51931 +401960 GAPDHP27 HGNC:HGNC:37779 +401967 NBPF17P MIM:612970|HGNC:HGNC:31997 +401973 OR10J6P HGNC:HGNC:14994 +401974 RPS2P10 HGNC:HGNC:36892 +401975 RPS3AP10 HGNC:HGNC:36036 +401981 FDPSP8 HGNC:HGNC:39085 +401982 AKR1B1P1 HGNC:HGNC:420 +401983 ZNF847P HGNC:HGNC:34384 +401992 OR2T2 HGNC:HGNC:14725|Ensembl:ENSG00000196240|Vega:OTTHUMG00000040480 +401993 OR2T5 HGNC:HGNC:15017|Ensembl:ENSG00000203661|Vega:OTTHUMG00000040481 +401994 OR14I1 HGNC:HGNC:19575|Ensembl:ENSG00000189181|Vega:OTTHUMG00000040378 +402016 BPIFB9P HGNC:HGNC:16109 +402055 SRRD MIM:602254|HGNC:HGNC:33910|Ensembl:ENSG00000100104|Vega:OTTHUMG00000150885 +402057 RPS17P16 HGNC:HGNC:36821 +402069 RPS16P2 HGNC:HGNC:35928 +402076 LOC402076 - +402077 OR7E46P HGNC:HGNC:8420 +402093 AHCYP3 HGNC:HGNC:44995 +402096 LOC402096 - +402100 RPL22P11 HGNC:HGNC:35603 +402112 HNRNPA1P39 HGNC:HGNC:48768 +402116 PKP4P1 HGNC:HGNC:42661 +402117 VWC2L HGNC:HGNC:37203|Ensembl:ENSG00000174453|Vega:OTTHUMG00000154811 +402120 RPL23P5 HGNC:HGNC:35747 +402123 RPSAP32 HGNC:HGNC:50310 +402125 HSPA8P18 HGNC:HGNC:44933 +402133 OR7E121P HGNC:HGNC:15049 +402134 KRT8P25 HGNC:HGNC:33377 +402135 OR5K2 HGNC:HGNC:14774|Ensembl:ENSG00000231861|Vega:OTTHUMG00000160049 +402143 HSPA8P9 HGNC:HGNC:44924 +402146 B3GAT3P1 HGNC:HGNC:35243 +402149 RPL28P1 HGNC:HGNC:31359 +402150 RPL8P4 HGNC:HGNC:35555 +402152 RPL7L1P8 HGNC:HGNC:39490 +402160 CFAP99 HGNC:HGNC:51180|Ensembl:ENSG00000206113|Vega:OTTHUMG00000160515 +402175 NDUFB4P12 HGNC:HGNC:45260 +402176 RPL21P44 HGNC:HGNC:33820 +402182 LOC402182 - +402183 RAC1P5 HGNC:HGNC:30593 +402184 RPS12P8 HGNC:HGNC:35945 +402191 NOL8P1 HGNC:HGNC:49557 +402192 LOC402192 - +402193 RPL5P11 HGNC:HGNC:35483 +402213 LOC402213 - +402214 RPL13AP13 HGNC:HGNC:36541 +402216 HNRNPH1P3 HGNC:HGNC:48811 +402220 YTHDF1P1 HGNC:HGNC:31681 +402221 LOC402221 - +402222 DDX18P4 HGNC:HGNC:33967 +402226 CCT5P1 HGNC:HGNC:35135 +402229 LOC402229 - +402230 LOC402230 - +402236 OR1X1P HGNC:HGNC:15062 +402240 OR1X5P HGNC:HGNC:31245 +402246 OR10AH1P HGNC:HGNC:19647 +402249 OR7E59P HGNC:HGNC:8434 +402273 VN1R37P HGNC:HGNC:37357 +402279 LOC402279 - +402287 RPS3AP21 HGNC:HGNC:36841 +402317 OR2A42 HGNC:HGNC:31230|Ensembl:ENSG00000212807|Vega:OTTHUMG00000157995 +402329 LOC402329 - +402333 OR7E160P HGNC:HGNC:31233 +402342 RPL13AP18 HGNC:HGNC:36593 +402359 KHSRPP1 HGNC:HGNC:39198 +402360 NOP56P2 HGNC:HGNC:49800 +402374 OR13D3P HGNC:HGNC:15106 +402375 YBX1P6 HGNC:HGNC:42427 +402381 SOHLH1 MIM:610224|HGNC:HGNC:27845|Ensembl:ENSG00000165643|Vega:OTTHUMG00000020915 +402394 IMPDH1P2 HGNC:HGNC:33957 +402408 PKMP2 HGNC:HGNC:44244 +402415 XKRX MIM:300684|HGNC:HGNC:29845|Ensembl:ENSG00000182489|Vega:OTTHUMG00000022010 +402420 EEF1A1P30 HGNC:HGNC:37906 +402422 TUBB4AP1 HGNC:HGNC:42340 +402424 OR13K1P HGNC:HGNC:14721 +402425 LOC402425 - +402429 KRT8P8 HGNC:HGNC:33362 +402483 LINC01000 HGNC:HGNC:38541 +402509 SLC29A4P1 HGNC:HGNC:43783 +402562 HNRNPA1P8 HGNC:HGNC:39126 +402569 KPNA7 MIM:614107|HGNC:HGNC:21839|Ensembl:ENSG00000185467|Vega:OTTHUMG00000154412 +402573 C7orf61 HGNC:HGNC:22135|Ensembl:ENSG00000185955|Vega:OTTHUMG00000150234 +402634 LOC402634 - +402635 GRIFIN HGNC:HGNC:4577 +402641 LOC402641 - +402643 TPM3P4 HGNC:HGNC:39167 +402644 LOC402644 - +402665 IGLON5 HGNC:HGNC:34550|Ensembl:ENSG00000142549|Vega:OTTHUMG00000154422 +402676 NDUFAF4P2 HGNC:HGNC:44541 +402679 MARK2P10 HGNC:HGNC:39801 +402682 UFSP1 MIM:611481|HGNC:HGNC:33821|Ensembl:ENSG00000176125|Vega:OTTHUMG00000159662 +402694 RPL15P11 HGNC:HGNC:36093 +402715 LOC402715 - +402716 RPL32P17 HGNC:HGNC:36251 +402778 IFITM10 HGNC:HGNC:40022|Ensembl:ENSG00000244242|Vega:OTTHUMG00000043933 +402779 CSMD2-AS1 HGNC:HGNC:40882|Ensembl:ENSG00000231163 +403150 FLJ31356 Ensembl:ENSG00000229951 +403219 OR7E157P HGNC:HGNC:31231 +403223 OR10AE3P HGNC:HGNC:31235 +403224 OR10AK1P HGNC:HGNC:31236 +403225 OR10V7P HGNC:HGNC:31237 +403226 OR11J5P HGNC:HGNC:31238 +403227 OR11Q1P HGNC:HGNC:31239 +403228 OR13Z1P HGNC:HGNC:31240 +403229 OR13Z2P HGNC:HGNC:31241 +403230 OR13Z3P HGNC:HGNC:31242 +403231 OR1AC1P HGNC:HGNC:31243 +403232 OR1M4P HGNC:HGNC:31244 +403234 OR2A41P HGNC:HGNC:31246 +403235 OR2AO1P HGNC:HGNC:31247 +403236 OR2AS2P HGNC:HGNC:31248 +403238 OR2BH1P HGNC:HGNC:31250 +403239 OR2T27 HGNC:HGNC:31252|Ensembl:ENSG00000187701|Vega:OTTHUMG00000040376 +403241 OR2T32P HGNC:HGNC:31254 +403244 OR2T35 HGNC:HGNC:31257|Ensembl:ENSG00000177151|Vega:OTTHUMG00000040380 +403245 OR2X1P HGNC:HGNC:31258 +403247 OR4A41P HGNC:HGNC:31260 +403248 OR4A42P HGNC:HGNC:31261 +403250 OR4A44P HGNC:HGNC:31263 +403251 OR4A45P HGNC:HGNC:31264 +403252 OR4A46P HGNC:HGNC:31265 +403253 OR4A47 HGNC:HGNC:31266|Ensembl:ENSG00000237388|Vega:OTTHUMG00000166581 +403254 OR4A48P HGNC:HGNC:31267 +403255 OR4A49P HGNC:HGNC:31268 +403256 OR4A50P HGNC:HGNC:31269 +403257 OR4C45 HGNC:HGNC:31270|Ensembl:ENSG00000260811 +403259 OR4C48P HGNC:HGNC:31272 +403260 OR4C49P HGNC:HGNC:31273 +403263 OR4G11P HGNC:HGNC:31276 +403264 OR4X7P HGNC:HGNC:31277 +403265 OR51AB1P HGNC:HGNC:31278 +403266 OR51B8P HGNC:HGNC:31279 +403271 OR5AC4P HGNC:HGNC:31284 +403272 OR5AO1P HGNC:HGNC:31285 +403273 OR5H14 HGNC:HGNC:31286|Ensembl:ENSG00000236032|Vega:OTTHUMG00000160079 +403274 OR5H15 HGNC:HGNC:31287|Ensembl:ENSG00000233412|Vega:OTTHUMG00000160076 +403275 OR9S24P HGNC:HGNC:31288 +403276 OR5J7P HGNC:HGNC:31289 +403277 OR5K3 HGNC:HGNC:31290|Ensembl:ENSG00000206536|Vega:OTTHUMG00000160077 +403278 OR5K4 HGNC:HGNC:31291|Ensembl:ENSG00000196098|Vega:OTTHUMG00000160081 +403281 OR6C64P HGNC:HGNC:31294 +403282 OR6C65 HGNC:HGNC:31295|Ensembl:ENSG00000205328|Vega:OTTHUMG00000169955 +403283 OR6C66P HGNC:HGNC:31296 +403284 OR6C68 HGNC:HGNC:31297|Ensembl:ENSG00000205327|Vega:OTTHUMG00000169958 +403285 OR6C69P HGNC:HGNC:31298 +403288 OR6C72P HGNC:HGNC:31301 +403289 OR6C73P HGNC:HGNC:31302 +403294 OR6R2P HGNC:HGNC:31307 +403295 OR7D11P HGNC:HGNC:31308 +403296 OR7E154P HGNC:HGNC:31309 +403297 OR7E155P HGNC:HGNC:31310 +403299 OR7E159P HGNC:HGNC:31312 +403300 OR7G15P HGNC:HGNC:31313 +403301 OR7H2P HGNC:HGNC:31314 +403302 OR8A3P HGNC:HGNC:31315 +403303 OR8I4P HGNC:HGNC:31316 +403304 OR8S21P HGNC:HGNC:31317 +403305 OR8X1P HGNC:HGNC:31318 +403312 LOC403312 - +403313 PLPP6 MIM:611666|HGNC:HGNC:23682|Ensembl:ENSG00000205808|Vega:OTTHUMG00000019466 +403314 APOBEC4 MIM:609908|HGNC:HGNC:32152|Ensembl:ENSG00000173627|Vega:OTTHUMG00000035459 +403315 FAM92A1P2 HGNC:HGNC:32287|Ensembl:ENSG00000230219 +403323 LOC403323 - +403339 DEFB133 HGNC:HGNC:31331|Ensembl:ENSG00000214643 +403340 MGC70870 - +403341 ZBTB34 MIM:611692|HGNC:HGNC:31446|Ensembl:ENSG00000177125|Vega:OTTHUMG00000020694 +404024 TRIM26BP HGNC:HGNC:31338 +404026 MTCO3P1 HGNC:HGNC:31342 +404037 HAPLN4 HGNC:HGNC:31357|Ensembl:ENSG00000187664|Vega:OTTHUMG00000182221 +404093 CUEDC1 HGNC:HGNC:31350|Ensembl:ENSG00000180891|Vega:OTTHUMG00000178775 +404199 PPIHP2 HGNC:HGNC:31356 +404201 WDFY3-AS2 HGNC:HGNC:21603|Ensembl:ENSG00000180769 +404203 SPINK6 MIM:615868|HGNC:HGNC:29486|Ensembl:ENSG00000178172|Vega:OTTHUMG00000163425 +404204 UGT1A13P HGNC:HGNC:32191 +404216 LINC01561 HGNC:HGNC:31365|Ensembl:ENSG00000177234 +404217 CTXN1 MIM:600135|HGNC:HGNC:31108|Ensembl:ENSG00000178531|Vega:OTTHUMG00000182480 +404220 C6orf201 HGNC:HGNC:21620|Ensembl:ENSG00000185689|Vega:OTTHUMG00000014160 +404266 HOXB-AS3 HGNC:HGNC:40283|Ensembl:ENSG00000233101 +404281 YY2 MIM:300570|HGNC:HGNC:31684|Ensembl:ENSG00000230797|Vega:OTTHUMG00000021236 +404542 DFNB50 HGNC:HGNC:31380 +404544 COX8BP HGNC:HGNC:31395 +404550 C16orf74 HGNC:HGNC:23362|Ensembl:ENSG00000154102|Vega:OTTHUMG00000183875 +404551 RWDD1P1 HGNC:HGNC:31055 +404552 SCGB1D4 MIM:615062|HGNC:HGNC:31748|Ensembl:ENSG00000197745|Vega:OTTHUMG00000167510 +404635 NANOGP1 HGNC:HGNC:23099 +404636 FAM45A HGNC:HGNC:31793|Ensembl:ENSG00000119979|Vega:OTTHUMG00000019143 +404663 LINC01194 MIM:617097|HGNC:HGNC:37171 +404665 CACTIN-AS1 HGNC:HGNC:31391|Ensembl:ENSG00000226800 +404672 GTF2H5 MIM:608780|HGNC:HGNC:21157|Ensembl:ENSG00000272047|Vega:OTTHUMG00000015906 +404677 CIMT MIM:608447 +404682 MYP5 MIM:608474|HGNC:HGNC:35433 +404683 BMIQ7 MIM:608410 +404684 PHOBS MIM:608251 +404685 RTE1 MIM:608045 +404686 SCZD11 MIM:608078 +404713 SSD MIM:608445 +404714 SLEB4 MIM:608437 +404715 PAFC MIM:128700 +404716 MTBS1 MIM:607949 +404718 GNRHR2P1 HGNC:HGNC:39424 +404719 HSCR8 MIM:608462 +404720 HSCR5 MIM:600156 +404734 ANKHD1-EIF4EBP3 HGNC:HGNC:33530|Ensembl:ENSG00000254996|Vega:OTTHUMG00000166212 +404744 NPSR1-AS1 MIM:608596|HGNC:HGNC:22128|Ensembl:ENSG00000197085 +404766 FABP5P4 HGNC:HGNC:31061 +404770 SPATA31B1P HGNC:HGNC:31411 +404785 POTEG MIM:608916|HGNC:HGNC:33896|Ensembl:ENSG00000187537|Vega:OTTHUMG00000170518 +405753 DUOXA2 MIM:612772|HGNC:HGNC:32698|Ensembl:ENSG00000140274|Vega:OTTHUMG00000131354 +405754 ERVFRD-1 MIM:610524|HGNC:HGNC:33823|Ensembl:ENSG00000244476|Vega:OTTHUMG00000159193 +406214 LRSL MIM:608545 +406215 KTCN3 MIM:608586 +406216 ATFB1 MIM:608583 +406237 PDON2 MIM:608526 +406238 ALS7 MIM:608031|HGNC:HGNC:34539 +406874 DYX8 MIM:608995|HGNC:HGNC:19951 +406875 FXYD6P3 HGNC:HGNC:31124 +406881 MIRLET7A1 MIM:605386|HGNC:HGNC:31476|Ensembl:ENSG00000199165|miRBase:MI0000060 +406882 MIRLET7A2 MIM:612142|HGNC:HGNC:31477|Ensembl:ENSG00000198975|miRBase:MI0000061 +406883 MIRLET7A3 MIM:612143|HGNC:HGNC:31478|Ensembl:ENSG00000283990|miRBase:MI0000062 +406884 MIRLET7B MIM:611249|HGNC:HGNC:31479|Ensembl:ENSG00000284520|miRBase:MI0000063 +406885 MIRLET7C MIM:612144|HGNC:HGNC:31480|Ensembl:ENSG00000199030|miRBase:MI0000064 +406886 MIRLET7D MIM:612145|HGNC:HGNC:31481|Ensembl:ENSG00000199133|miRBase:MI0000065 +406887 MIRLET7E MIM:611250|HGNC:HGNC:31482|Ensembl:ENSG00000198972|miRBase:MI0000066 +406888 MIRLET7F1 MIM:612146|HGNC:HGNC:31483|Ensembl:ENSG00000199072|miRBase:MI0000067 +406889 MIRLET7F2 MIM:300721|HGNC:HGNC:31484|Ensembl:ENSG00000208012|miRBase:MI0000068 +406890 MIRLET7G MIM:612102|HGNC:HGNC:31485|Ensembl:ENSG00000199150|miRBase:MI0000433 +406891 MIRLET7I MIM:612148|HGNC:HGNC:31486|Ensembl:ENSG00000199179|miRBase:MI0000434 +406892 MIR100 MIM:613186|HGNC:HGNC:31487|Ensembl:ENSG00000207994|miRBase:MI0000102 +406893 MIR101-1 MIM:612511|HGNC:HGNC:31488|Ensembl:ENSG00000199135|miRBase:MI0000103 +406894 MIR101-2 MIM:612512|HGNC:HGNC:31489|Ensembl:ENSG00000199065|miRBase:MI0000739 +406895 MIR103A1 MIM:613187|HGNC:HGNC:31490|Ensembl:ENSG00000199035|miRBase:MI0000109 +406896 MIR103A2 MIM:613188|HGNC:HGNC:31491|Ensembl:ENSG00000199024|miRBase:MI0000108 +406897 MIR105-1 MIM:300811|HGNC:HGNC:31492|Ensembl:ENSG00000207957|miRBase:MI0000111 +406898 MIR105-2 MIM:300812|HGNC:HGNC:31493|Ensembl:ENSG00000207818|miRBase:MI0000112 +406899 MIR106A MIM:300792|HGNC:HGNC:31494|Ensembl:ENSG00000284157|miRBase:MI0000113 +406900 MIR106B MIM:612983|HGNC:HGNC:31495|Ensembl:ENSG00000208036|miRBase:MI0000734 +406901 MIR107 MIM:613189|HGNC:HGNC:31496|Ensembl:ENSG00000198997|miRBase:MI0000114 +406902 MIR10A MIM:610173|HGNC:HGNC:31497|Ensembl:ENSG00000284038|miRBase:MI0000266 +406903 MIR10B MIM:611576|HGNC:HGNC:31498|Ensembl:ENSG00000207744|miRBase:MI0000267 +406904 MIR1-1 MIM:609326|HGNC:HGNC:31499|Ensembl:ENSG00000199017|miRBase:MI0000651 +406905 MIR1-2 MIM:610252|HGNC:HGNC:31500|Ensembl:ENSG00000284453|miRBase:MI0000437 +406906 MIR122 MIM:609582|HGNC:HGNC:31501|Ensembl:ENSG00000284440|miRBase:MI0000442 +406907 MIR124-1 MIM:609327|HGNC:HGNC:31502|Ensembl:ENSG00000284321|miRBase:MI0000443 +406908 MIR124-2 HGNC:HGNC:31503|Ensembl:ENSG00000207816|miRBase:MI0000444 +406909 MIR124-3 HGNC:HGNC:31504|Ensembl:ENSG00000207598|miRBase:MI0000445 +406910 MIR125A MIM:611191|HGNC:HGNC:31505|Ensembl:ENSG00000208008|miRBase:MI0000469 +406911 MIR125B1 MIM:610104|HGNC:HGNC:31506|Ensembl:ENSG00000207971|miRBase:MI0000446 +406912 MIR125B2 MIM:610105|HGNC:HGNC:31507|Ensembl:ENSG00000207863|miRBase:MI0000470 +406913 MIR126 MIM:611767|HGNC:HGNC:31508|Ensembl:ENSG00000199161|miRBase:MI0000471 +406914 MIR127 MIM:611709|HGNC:HGNC:31509|Ensembl:ENSG00000207608|miRBase:MI0000472 +406915 MIR128-1 MIM:611774|HGNC:HGNC:31510|Ensembl:ENSG00000207654|miRBase:MI0000447 +406916 MIR128-2 MIM:611769|HGNC:HGNC:31511|Ensembl:ENSG00000207625|miRBase:MI0000727 +406917 MIR129-1 HGNC:HGNC:31512|Ensembl:ENSG00000207705|miRBase:MI0000252 +406918 MIR129-2 HGNC:HGNC:31513|Ensembl:ENSG00000199077|miRBase:MI0000473 +406919 MIR130A MIM:610175|HGNC:HGNC:31514|Ensembl:ENSG00000208009|miRBase:MI0000448 +406920 MIR130B MIM:613682|HGNC:HGNC:31515|Ensembl:ENSG00000283871|miRBase:MI0000748 +406921 MIR132 MIM:610016|HGNC:HGNC:31516|Ensembl:ENSG00000267200|miRBase:MI0000449 +406922 MIR133A1 MIM:610254|HGNC:HGNC:31517|Ensembl:ENSG00000283927|miRBase:MI0000450 +406923 MIR133A2 MIM:610255|HGNC:HGNC:31518|Ensembl:ENSG00000284508|miRBase:MI0000451 +406924 MIR134 MIM:610164|HGNC:HGNC:31519|Ensembl:ENSG00000207993|miRBase:MI0000474 +406925 MIR135A1 HGNC:HGNC:31520|Ensembl:ENSG00000207926|miRBase:MI0000452 +406926 MIR135A2 HGNC:HGNC:31521|Ensembl:ENSG00000207586|miRBase:MI0000453 +406927 MIR136 MIM:611710|HGNC:HGNC:31522|Ensembl:ENSG00000207942|miRBase:MI0000475 +406928 MIR137 MIM:614304|HGNC:HGNC:31523|Ensembl:ENSG00000284202|miRBase:MI0000454 +406929 MIR138-1 MIM:613394|HGNC:HGNC:31524|Ensembl:ENSG00000207954|miRBase:MI0000476 +406930 MIR138-2 MIM:613395|HGNC:HGNC:31525|Ensembl:ENSG00000207649|miRBase:MI0000455 +406931 MIR139 MIM:615017|HGNC:HGNC:31526|Ensembl:ENSG00000272036|miRBase:MI0000261 +406932 MIR140 MIM:611894|HGNC:HGNC:31527|Ensembl:ENSG00000208017|miRBase:MI0000456 +406933 MIR141 MIM:612093|HGNC:HGNC:31528|Ensembl:ENSG00000207708|miRBase:MI0000457 +406934 MIR142 MIM:615657|HGNC:HGNC:31529|Ensembl:ENSG00000284353|miRBase:MI0000458 +406935 MIR143 MIM:612117|HGNC:HGNC:31530|Ensembl:ENSG00000284182|miRBase:MI0000459 +406936 MIR144 MIM:612070|HGNC:HGNC:31531|Ensembl:ENSG00000283819|miRBase:MI0000460 +406937 MIR145 MIM:611795|HGNC:HGNC:31532|Ensembl:ENSG00000276365|miRBase:MI0000461 +406938 MIR146A MIM:610566|HGNC:HGNC:31533|Ensembl:ENSG00000283733|miRBase:MI0000477 +406939 MIR147A HGNC:HGNC:31534|Ensembl:ENSG00000207814|miRBase:MI0000262 +406940 MIR148A MIM:613786|HGNC:HGNC:31535|Ensembl:ENSG00000199085|miRBase:MI0000253 +406941 MIR149 MIM:615209|HGNC:HGNC:31536|Ensembl:ENSG00000207611|miRBase:MI0000478 +406942 MIR150 MIM:611114|HGNC:HGNC:31537|Ensembl:ENSG00000207782|miRBase:MI0000479 +406943 MIR152 MIM:613788|HGNC:HGNC:31538|Ensembl:ENSG00000207947|miRBase:MI0000462 +406944 MIR153-1 HGNC:HGNC:31539|Ensembl:ENSG00000207647|miRBase:MI0000463 +406945 MIR153-2 HGNC:HGNC:31540|Ensembl:ENSG00000207960|miRBase:MI0000464 +406946 MIR154 HGNC:HGNC:31541|Ensembl:ENSG00000207978|miRBase:MI0000480 +406947 MIR155 MIM:609337|HGNC:HGNC:31542|Ensembl:ENSG00000283904|miRBase:MI0000681 +406948 MIR15A MIM:609703|HGNC:HGNC:31543|Ensembl:ENSG00000283785|miRBase:MI0000069 +406949 MIR15B HGNC:HGNC:31544|Ensembl:ENSG00000207779|miRBase:MI0000438 +406950 MIR16-1 MIM:609704|HGNC:HGNC:31545|Ensembl:ENSG00000208006|miRBase:MI0000070 +406951 MIR16-2 HGNC:HGNC:31546|Ensembl:ENSG00000198987|miRBase:MI0000115 +406952 MIR17 MIM:609416|HGNC:HGNC:31547|Ensembl:ENSG00000284536|miRBase:MI0000071 +406953 MIR18A MIM:609417|HGNC:HGNC:31548|Ensembl:ENSG00000283815|miRBase:MI0000072 +406954 MIR181A2 MIM:612743|HGNC:HGNC:31549|Ensembl:ENSG00000207595|miRBase:MI0000269 +406955 MIR181B1 MIM:612744|HGNC:HGNC:31550|Ensembl:ENSG00000207975|miRBase:MI0000270 +406956 MIR181B2 MIM:612745|HGNC:HGNC:31551|Ensembl:ENSG00000207737|miRBase:MI0000683 +406957 MIR181C MIM:612746|HGNC:HGNC:31552|Ensembl:ENSG00000207613|miRBase:MI0000271 +406958 MIR182 MIM:611607|HGNC:HGNC:31553|Ensembl:ENSG00000207990|miRBase:MI0000272 +406959 MIR183 MIM:611608|HGNC:HGNC:31554|Ensembl:ENSG00000207691|miRBase:MI0000273 +406960 MIR184 MIM:613146|HGNC:HGNC:31555|Ensembl:ENSG00000207695|miRBase:MI0000481 +406961 MIR185 MIM:615576|HGNC:HGNC:31556|Ensembl:ENSG00000208023|miRBase:MI0000482 +406962 MIR186 HGNC:HGNC:31557|Ensembl:ENSG00000207721|miRBase:MI0000483 +406963 MIR187 MIM:612698|HGNC:HGNC:31558|Ensembl:ENSG00000207797|miRBase:MI0000274 +406964 MIR188 HGNC:HGNC:31559|Ensembl:ENSG00000207768|miRBase:MI0000484 +406965 MIR190A MIM:615845|HGNC:HGNC:31560|Ensembl:ENSG00000211137|miRBase:MI0000486 +406966 MIR191 MIM:615150|HGNC:HGNC:31561|Ensembl:ENSG00000207605|miRBase:MI0000465 +406967 MIR192 MIM:610939|HGNC:HGNC:31562|Ensembl:ENSG00000283926|miRBase:MI0000234 +406968 MIR193A MIM:614733|HGNC:HGNC:31563|Ensembl:ENSG00000207614|miRBase:MI0000487 +406969 MIR194-1 MIM:610940|HGNC:HGNC:31564|Ensembl:ENSG00000207624|miRBase:MI0000488 +406970 MIR194-2 MIM:610941|HGNC:HGNC:31565|Ensembl:ENSG00000284155|miRBase:MI0000732 +406971 MIR195 MIM:610718|HGNC:HGNC:31566|Ensembl:ENSG00000284112|miRBase:MI0000489 +406972 MIR196A1 MIM:608632|HGNC:HGNC:31567|Ensembl:ENSG00000210741|miRBase:MI0000238 +406973 MIR196A2 MIM:609687|HGNC:HGNC:31568|Ensembl:ENSG00000207924|miRBase:MI0000279 +406974 MIR197 MIM:611189|HGNC:HGNC:31569|Ensembl:ENSG00000284443|miRBase:MI0000239 +406975 MIR198 HGNC:HGNC:31570|Ensembl:ENSG00000284121|miRBase:MI0000240 +406976 MIR199A1 MIM:610719|HGNC:HGNC:31571|Ensembl:ENSG00000207752|miRBase:MI0000242 +406977 MIR199A2 MIM:610720|HGNC:HGNC:31572|Ensembl:ENSG00000208024|miRBase:MI0000281 +406978 MIR199B MIM:614791|HGNC:HGNC:31573|Ensembl:ENSG00000207581|miRBase:MI0000282 +406979 MIR19A MIM:609418|HGNC:HGNC:31574|Ensembl:ENSG00000284204|miRBase:MI0000073 +406980 MIR19B1 MIM:609419|HGNC:HGNC:31575|Ensembl:ENSG00000284375|miRBase:MI0000074 +406981 MIR19B2 MIM:300722|HGNC:HGNC:31576|Ensembl:ENSG00000284107|miRBase:MI0000075 +406982 MIR20A MIM:609420|HGNC:HGNC:31577|Ensembl:ENSG00000283762|miRBase:MI0000076 +406983 MIR200A MIM:612090|HGNC:HGNC:31578|Ensembl:ENSG00000207607|miRBase:MI0000737 +406984 MIR200B MIM:612091|HGNC:HGNC:31579|Ensembl:ENSG00000207730|miRBase:MI0000342 +406985 MIR200C MIM:612092|HGNC:HGNC:31580|Ensembl:ENSG00000207713|miRBase:MI0000650 +406986 MIR203A MIM:611899|HGNC:HGNC:31581|Ensembl:ENSG00000207568|miRBase:MI0000283 +406987 MIR204 MIM:610942|HGNC:HGNC:31582|Ensembl:ENSG00000207935|miRBase:MI0000284 +406988 MIR205 MIM:613147|HGNC:HGNC:31583|Ensembl:ENSG00000284485|miRBase:MI0000285 +406989 MIR206 MIM:611599|HGNC:HGNC:31584|Ensembl:ENSG00000207604|miRBase:MI0000490 +406990 MIR208A MIM:611116|HGNC:HGNC:31585|Ensembl:ENSG00000199157|miRBase:MI0000251 +406991 MIR21 MIM:611020|HGNC:HGNC:31586|Ensembl:ENSG00000284190|miRBase:MI0000077 +406992 MIR210 MIM:612982|HGNC:HGNC:31587|Ensembl:ENSG00000199038|miRBase:MI0000286 +406993 MIR211 MIM:613753|HGNC:HGNC:31588|Ensembl:ENSG00000207702|miRBase:MI0000287 +406994 MIR212 MIM:613487|HGNC:HGNC:31589|Ensembl:ENSG00000267195|miRBase:MI0000288 +406995 MIR181A1 MIM:612742|HGNC:HGNC:31590|Ensembl:ENSG00000207759|miRBase:MI0000289 +406996 MIR214 MIM:610721|HGNC:HGNC:31591|Ensembl:ENSG00000283844|miRBase:MI0000290 +406997 MIR215 MIM:610943|HGNC:HGNC:31592|Ensembl:ENSG00000207590|miRBase:MI0000291 +406998 MIR216A MIM:610944|HGNC:HGNC:31593|Ensembl:ENSG00000207798|miRBase:MI0000292 +406999 MIR217 MIM:615096|HGNC:HGNC:31594|Ensembl:ENSG00000207548|miRBase:MI0000293 +407000 MIR218-1 MIM:616770|HGNC:HGNC:31595|Ensembl:ENSG00000207732|miRBase:MI0000294 +407001 MIR218-2 MIM:616771|HGNC:HGNC:31596|Ensembl:ENSG00000207739|miRBase:MI0000295 +407002 MIR219A1 MIM:611500|HGNC:HGNC:31597|Ensembl:ENSG00000199036|miRBase:MI0000296 +407003 MIR219A2 HGNC:HGNC:31598|Ensembl:ENSG00000284185|miRBase:MI0000740 +407004 MIR22 MIM:612077|HGNC:HGNC:31599|Ensembl:ENSG00000283824|miRBase:MI0000078 +407006 MIR221 MIM:300568|HGNC:HGNC:31601|Ensembl:ENSG00000207870|miRBase:MI0000298 +407007 MIR222 MIM:300569|HGNC:HGNC:31602|Ensembl:ENSG00000207725|miRBase:MI0000299 +407008 MIR223 MIM:300694|HGNC:HGNC:31603|Ensembl:ENSG00000284567|miRBase:MI0000300 +407009 MIR224 MIM:300769|HGNC:HGNC:31604|Ensembl:ENSG00000284363|miRBase:MI0000301 +407010 MIR23A MIM:607962|HGNC:HGNC:31605|Ensembl:ENSG00000207980|miRBase:MI0000079 +407011 MIR23B MIM:610723|HGNC:HGNC:31606|Ensembl:ENSG00000207563|miRBase:MI0000439 +407012 MIR24-1 MIM:609705|HGNC:HGNC:31607|Ensembl:ENSG00000284459|miRBase:MI0000080 +407013 MIR24-2 MIM:610724|HGNC:HGNC:31608|Ensembl:ENSG00000284387|miRBase:MI0000081 +407014 MIR25 MIM:612150|HGNC:HGNC:31609|Ensembl:ENSG00000207547|miRBase:MI0000082 +407015 MIR26A1 MIM:612151|HGNC:HGNC:31610|Ensembl:ENSG00000199075|miRBase:MI0000083 +407016 MIR26A2 MIM:613057|HGNC:HGNC:31611|Ensembl:ENSG00000207789|miRBase:MI0000750 +407017 MIR26B MIM:612152|HGNC:HGNC:31612|Ensembl:ENSG00000199121|miRBase:MI0000084 +407018 MIR27A MIM:612153|HGNC:HGNC:31613|Ensembl:ENSG00000207808|miRBase:MI0000085 +407019 MIR27B MIM:610636|HGNC:HGNC:31614|Ensembl:ENSG00000207864|miRBase:MI0000440 +407020 MIR28 MIM:612154|HGNC:HGNC:31615|Ensembl:ENSG00000207651|miRBase:MI0000086 +407021 MIR29A MIM:610782|HGNC:HGNC:31616|Ensembl:ENSG00000284032|miRBase:MI0000087 +407022 MIR296 MIM:610945|HGNC:HGNC:31617|Ensembl:ENSG00000284040|miRBase:MI0000747 +407023 MIR299 HGNC:HGNC:31618|Ensembl:ENSG00000207749|miRBase:MI0000744 +407024 MIR29B1 MIM:610783|HGNC:HGNC:31619|Ensembl:ENSG00000283797|miRBase:MI0000105 +407025 MIR29B2 HGNC:HGNC:31620|Ensembl:ENSG00000284203|miRBase:MI0000107 +407026 MIR29C MIM:610784|HGNC:HGNC:31621|Ensembl:ENSG00000284214|miRBase:MI0000735 +407027 MIR301A MIM:615675|HGNC:HGNC:31622|Ensembl:ENSG00000207996|miRBase:MI0000745 +407028 MIR302A MIM:614596|HGNC:HGNC:31623|Ensembl:ENSG00000207927|miRBase:MI0000738 +407029 MIR30A MIM:612329|HGNC:HGNC:31624|Ensembl:ENSG00000207827|miRBase:MI0000088 +407030 MIR30B HGNC:HGNC:31625|Ensembl:ENSG00000207582|miRBase:MI0000441 +407031 MIR30C1 MIM:615151|HGNC:HGNC:31626|Ensembl:ENSG00000207962|miRBase:MI0000736 +407032 MIR30C2 HGNC:HGNC:31627|Ensembl:ENSG00000199094|miRBase:MI0000254 +407033 MIR30D HGNC:HGNC:31628|Ensembl:ENSG00000199153|miRBase:MI0000255 +407034 MIR30E HGNC:HGNC:31629|Ensembl:ENSG00000198974|miRBase:MI0000749 +407035 MIR31 MIM:612155|HGNC:HGNC:31630|Ensembl:ENSG00000199177|miRBase:MI0000089 +407036 MIR32 MIM:609355|HGNC:HGNC:31631|Ensembl:ENSG00000207698|miRBase:MI0000090 +407037 MIR320A MIM:614112|HGNC:HGNC:31632|Ensembl:ENSG00000208037|miRBase:MI0000542 +407039 MIR33A MIM:612156|HGNC:HGNC:31634|Ensembl:ENSG00000207932|miRBase:MI0000091 +407040 MIR34A MIM:611172|HGNC:HGNC:31635|Ensembl:ENSG00000284357|miRBase:MI0000268 +407041 MIR34B MIM:611374|HGNC:HGNC:31636|Ensembl:ENSG00000207811|miRBase:MI0000742 +407042 MIR34C MIM:611375|HGNC:HGNC:31637|Ensembl:ENSG00000207562|miRBase:MI0000743 +407043 MIR7-1 MIM:615239|HGNC:HGNC:31638|Ensembl:ENSG00000284179|miRBase:MI0000263 +407044 MIR7-2 HGNC:HGNC:31639|Ensembl:ENSG00000207703|miRBase:MI0000264 +407045 MIR7-3 HGNC:HGNC:31640|Ensembl:ENSG00000207630|miRBase:MI0000265 +407046 MIR9-1 MIM:611186|HGNC:HGNC:31641|Ensembl:ENSG00000207933|miRBase:MI0000466 +407047 MIR9-2 MIM:611187|HGNC:HGNC:31642|Ensembl:ENSG00000284447|miRBase:MI0000467 +407048 MIR92A1 MIM:609422|HGNC:HGNC:31643|Ensembl:ENSG00000283705|miRBase:MI0000093 +407049 MIR92A2 HGNC:HGNC:31644|Ensembl:ENSG00000284538|miRBase:MI0000094 +407050 MIR93 MIM:612984|HGNC:HGNC:31645|Ensembl:ENSG00000207757|miRBase:MI0000095 +407051 MIR9-3 MIM:611188|HGNC:HGNC:31646|Ensembl:ENSG00000284329|miRBase:MI0000468 +407052 MIR95 MIM:613185|HGNC:HGNC:31647|Ensembl:ENSG00000207807|miRBase:MI0000097 +407053 MIR96 MIM:611606|HGNC:HGNC:31648|Ensembl:ENSG00000199158|miRBase:MI0000098 +407054 MIR98 MIM:300810|HGNC:HGNC:31649|Ensembl:ENSG00000271886|miRBase:MI0000100 +407055 MIR99A MIM:614509|HGNC:HGNC:31650|Ensembl:ENSG00000207638|miRBase:MI0000101 +407056 MIR99B MIM:614510|HGNC:HGNC:31651|Ensembl:ENSG00000207550|miRBase:MI0000746 +407738 FAM19A1 MIM:617495|HGNC:HGNC:21587|Ensembl:ENSG00000183662|Vega:OTTHUMG00000158745 +407835 LOC407835 - +407973 SCA20 MIM:608687|HGNC:HGNC:17204 +407975 MIR17HG MIM:609415|HGNC:HGNC:23564|Ensembl:ENSG00000215417 +407977 TNFSF12-TNFSF13 HGNC:HGNC:33537|Ensembl:ENSG00000248871|Vega:OTTHUMG00000161573 +408029 C2orf27B HGNC:HGNC:33824 +408050 NOMO3 MIM:609159|HGNC:HGNC:25242|Ensembl:ENSG00000103226|Vega:OTTHUMG00000177317 +408186 OVOS Ensembl:ENSG00000214776 +408187 SPINK14 HGNC:HGNC:33825|Ensembl:ENSG00000196800|Vega:OTTHUMG00000129732 +408221 SCA26 MIM:609306|HGNC:HGNC:31097 +408257 CILD4 MIM:608646 +408259 HPC3 MIM:608656 +408260 HPC4 MIM:608658 +408263 FNDC9 HGNC:HGNC:33547|Ensembl:ENSG00000172568|Vega:OTTHUMG00000130248 +414058 ACRPV MIM:102510 +414059 TBC1D3B MIM:610144|HGNC:HGNC:27011|Ensembl:ENSG00000274808|Vega:OTTHUMG00000188417 +414060 TBC1D3C MIM:610806|HGNC:HGNC:24889|Ensembl:ENSG00000278299|Vega:OTTHUMG00000188484 +414061 DNAJB3 HGNC:HGNC:32397 +414062 CCL3L3 MIM:609468|HGNC:HGNC:30554|Ensembl:ENSG00000276085|Vega:OTTHUMG00000188419 +414130 NANOGP7 HGNC:HGNC:23105 +414131 NANOGP2 HGNC:HGNC:23100 +414132 NANOGP4 HGNC:HGNC:23102 +414133 NANOGP5 HGNC:HGNC:23103 +414134 NANOGP6 HGNC:HGNC:23104 +414135 NANOGP11 HGNC:HGNC:32941 +414149 ACBD7 HGNC:HGNC:17715|Ensembl:ENSG00000176244|Vega:OTTHUMG00000017725 +414152 C10orf105 HGNC:HGNC:20304|Ensembl:ENSG00000214688|Vega:OTTHUMG00000018427 +414153 SNRPEP2 HGNC:HGNC:20733 +414157 C10orf62 HGNC:HGNC:23294|Ensembl:ENSG00000203942|Vega:OTTHUMG00000018858 +414169 BANF1P2 HGNC:HGNC:23426 +414189 AGAP6 HGNC:HGNC:23466|Ensembl:ENSG00000204149|Vega:OTTHUMG00000018220 +414194 CCNYL2 HGNC:HGNC:23495|Ensembl:ENSG00000182632 +414196 CELF2-AS1 HGNC:HGNC:23515 +414197 ZNF32-AS1 HGNC:HGNC:23577|Ensembl:ENSG00000226245 +414200 NHP2P1 HGNC:HGNC:23582 +414201 ZNF32-AS3 HGNC:HGNC:23583|Ensembl:ENSG00000223910 +414208 ZNF32-AS2 HGNC:HGNC:23593|Ensembl:ENSG00000230565 +414212 GLUD1P7 HGNC:HGNC:23636|Ensembl:ENSG00000265366 +414213 GLUD1P8 HGNC:HGNC:23637 +414217 BMS1P3 HGNC:HGNC:23651 +414224 AGAP12P HGNC:HGNC:23661|Ensembl:ENSG00000265018 +414228 RPS27P1 HGNC:HGNC:23740 +414230 RPS15AP5 HGNC:HGNC:23743 +414235 PRR26 HGNC:HGNC:30724|Ensembl:ENSG00000180525|Vega:OTTHUMG00000017529 +414236 C10orf55 HGNC:HGNC:31008|Ensembl:ENSG00000222047 +414241 FAM35BP HGNC:HGNC:31425|Ensembl:ENSG00000165874 +414243 LINC00595 HGNC:HGNC:31430|Ensembl:ENSG00000230417 +414245 DNAJC9-AS1 HGNC:HGNC:31432|Ensembl:ENSG00000227540|Ensembl:ENSG00000236756 +414254 RPSAP6 HGNC:HGNC:31458 +414260 LINC00619 HGNC:HGNC:31657|Ensembl:ENSG00000204187 +414300 LOC414300 - +414301 DDI1 HGNC:HGNC:18961|Ensembl:ENSG00000170967|Vega:OTTHUMG00000165990 +414312 C9orf118 HGNC:HGNC:25943 +414316 COL5A1-AS1 HGNC:HGNC:31368 +414318 C9orf106 HGNC:HGNC:31370 +414319 LINC00587 HGNC:HGNC:31372|Ensembl:ENSG00000204250 +414325 DEFB103A HGNC:HGNC:15967|Ensembl:ENSG00000176797|Vega:OTTHUMG00000143855 +414328 IDNK MIM:611343|HGNC:HGNC:31367|Ensembl:ENSG00000148057|Vega:OTTHUMG00000020105 +414332 LCN10 MIM:612904|HGNC:HGNC:20892|Ensembl:ENSG00000187922|Vega:OTTHUMG00000150428 +414351 LINC00229 HGNC:HGNC:13240 +414355 VKORC1P1 HGNC:HGNC:33182 +414357 VKORC1P2 HGNC:HGNC:33183 +414751 TRAPPC2P8 HGNC:HGNC:37731 +414752 TRAPPC2P10 HGNC:HGNC:37732 +414753 TRAPPC2P9 HGNC:HGNC:37733 +414754 ACTG1P11 HGNC:HGNC:37651 +414760 HCG14 HGNC:HGNC:18323|Ensembl:ENSG00000224157 +414761 HCG15 HGNC:HGNC:18361 +414763 BMS1P18 HGNC:HGNC:19436 +414764 HCG23 HGNC:HGNC:19713|Ensembl:ENSG00000228962 +414765 HCG25 HGNC:HGNC:20196|Ensembl:ENSG00000232940 +414768 HCG24 HGNC:HGNC:23500 +414771 DDR1-AS1 HGNC:HGNC:28694 +414776 HCG19P HGNC:HGNC:31336 +414777 HCG18 HGNC:HGNC:31337 +414778 HCG17 HGNC:HGNC:31339|Ensembl:ENSG00000270604 +414886 SPG27 MIM:609041|HGNC:HGNC:26071 +414899 BLID MIM:608853|HGNC:HGNC:33495|Ensembl:ENSG00000259571|Vega:OTTHUMG00000166060 +414918 DENND6B HGNC:HGNC:32690|Ensembl:ENSG00000205593|Vega:OTTHUMG00000150210 +414919 C8orf82 HGNC:HGNC:33826|Ensembl:ENSG00000213563|Vega:OTTHUMG00000165181 +414926 LINC00593 HGNC:HGNC:32382|Ensembl:ENSG00000259703 +414927 MGC34796 - +415056 CNTFR-AS1 HGNC:HGNC:48712 +415116 PIM3 MIM:610580|HGNC:HGNC:19310|Ensembl:ENSG00000198355|Vega:OTTHUMG00000150290 +415117 STX19 HGNC:HGNC:19300|Ensembl:ENSG00000178750|Vega:OTTHUMG00000159013 +425054 VCX3B MIM:300981|HGNC:HGNC:31838|Ensembl:ENSG00000205642|Vega:OTTHUMG00000021106 +425057 TTTY9B HGNC:HGNC:32425|Ensembl:ENSG00000131007 +431704 RGS21 MIM:612407|HGNC:HGNC:26839|Ensembl:ENSG00000253148|Vega:OTTHUMG00000035594 +431705 ASTL MIM:608860|HGNC:HGNC:31704|Ensembl:ENSG00000188886|Vega:OTTHUMG00000155212 +431707 LHX8 MIM:604425|HGNC:HGNC:28838|Ensembl:ENSG00000162624|Vega:OTTHUMG00000009692 +431708 MDD1 MIM:608520 +431709 MDD2 MIM:608691 +431710 ASPG1 MIM:608638 +431711 ASPG2 MIM:608631 +431712 CMT2G MIM:608591 +432369 ATP5EP2 HGNC:HGNC:34026|Ensembl:ENSG00000180389|Vega:OTTHUMG00000016642 +432400 EIG3 MIM:608762 +439915 KRTAP5-5 HGNC:HGNC:23601|Ensembl:ENSG00000185940|Vega:OTTHUMG00000057554 +439916 LINC00615 HGNC:HGNC:26343|Ensembl:ENSG00000196243 +439921 MXRA7 HGNC:HGNC:7541|Ensembl:ENSG00000182534|Vega:OTTHUMG00000180370 +439927 LINC01555 HGNC:HGNC:26647|Ensembl:ENSG00000180869 +439931 THAP7-AS1 HGNC:HGNC:41013|Ensembl:ENSG00000230513 +439933 LOC439933 Ensembl:ENSG00000247193 +439934 LINC00575 HGNC:HGNC:21342|Ensembl:ENSG00000231782 +439936 C5orf17 HGNC:HGNC:26630|Ensembl:ENSG00000248874 +439941 FER1L6-AS1 HGNC:HGNC:26652|Ensembl:ENSG00000181171 +439945 IL9RP2 HGNC:HGNC:6032 +439949 PRKCQ-AS1 HGNC:HGNC:44689 +439950 CELF2-AS2 HGNC:HGNC:44703 +439953 PPIAP31 HGNC:HGNC:44962 +439954 RPL7P37 HGNC:HGNC:36656 +439957 IGKV1ORY-1 HGNC:HGNC:37729|IMGT/GENE-DB:IGKV1/ORY-1 +439965 FAM35DP HGNC:HGNC:34038 +439990 LINC00857 HGNC:HGNC:45114|Ensembl:ENSG00000237523 +439992 RPS3AP5 HGNC:HGNC:23744 +439994 LINC00863 HGNC:HGNC:45162|Ensembl:ENSG00000224914 +439996 IFIT1B HGNC:HGNC:23442|Ensembl:ENSG00000204010|Vega:OTTHUMG00000018709 +440013 DUX4L10 HGNC:HGNC:31354 +440014 DUX4L12 HGNC:HGNC:38671 +440017 DUX4L15 HGNC:HGNC:38674 +440021 KRTAP5-2 HGNC:HGNC:23597|Ensembl:ENSG00000205867|Vega:OTTHUMG00000165547 +440023 KRTAP5-6 HGNC:HGNC:23600|Ensembl:ENSG00000205864|Vega:OTTHUMG00000043932 +440026 TMEM41B HGNC:HGNC:28948|Ensembl:ENSG00000166471|Vega:OTTHUMG00000165719 +440027 RPL23AP65 HGNC:HGNC:36289 +440028 LOC440028 Ensembl:ENSG00000245522 +440031 LOC440031 - +440034 PAX6-AS1 HGNC:HGNC:53448|Ensembl:ENSG00000049449 +440040 LOC440040 Ensembl:ENSG00000205035 +440041 TRIM51HP HGNC:HGNC:43977 +440043 PGAM1P8 HGNC:HGNC:42455 +440044 SLC22A20 MIM:611696|HGNC:HGNC:29867|Ensembl:ENSG00000197847 +440050 KRTAP5-7 HGNC:HGNC:23602|Ensembl:ENSG00000244411|Vega:OTTHUMG00000057570 +440051 KRTAP5-11 HGNC:HGNC:23606|Ensembl:ENSG00000204571|Vega:OTTHUMG00000057586 +440055 RPS12P22 HGNC:HGNC:35671 +440059 LOC440059 - +440061 TRIM64EP HGNC:HGNC:43975 +440063 LOC440063 - +440067 CASP1P2 HGNC:HGNC:43776 +440068 CARD17 MIM:609490|HGNC:HGNC:33827|Ensembl:ENSG00000255221|Vega:OTTHUMG00000166163 +440072 LINC00167 HGNC:HGNC:30468 +440073 IQSEC3 MIM:612118|HGNC:HGNC:29193|Ensembl:ENSG00000120645|Vega:OTTHUMG00000167975 +440077 ZNF705A HGNC:HGNC:32281|Ensembl:ENSG00000196946|Vega:OTTHUMG00000168635 +440078 FAM66C HGNC:HGNC:21644|Ensembl:ENSG00000226711 +440081 DDX12P MIM:601151|HGNC:HGNC:2737 +440084 LOC440084 Ensembl:ENSG00000255790 +440086 RPS6P1 HGNC:HGNC:32478 +440087 SMCO3 HGNC:HGNC:34401|Ensembl:ENSG00000179256|Vega:OTTHUMG00000167474 +440093 H3F3C MIM:616134|HGNC:HGNC:33164|Ensembl:ENSG00000188375|Vega:OTTHUMG00000157811 +440097 DBX2 HGNC:HGNC:33186|Ensembl:ENSG00000185610|Vega:OTTHUMG00000169559 +440101 FLJ12825 Ensembl:ENSG00000248265 +440104 TMEM198B HGNC:HGNC:43629|Ensembl:ENSG00000182796 +440107 PLEKHG7 HGNC:HGNC:33829|Ensembl:ENSG00000187510|Vega:OTTHUMG00000170106 +440117 LINC02372 HGNC:HGNC:53294|Ensembl:ENSG00000249873 +440119 FZD10-AS1 HGNC:HGNC:48632|Ensembl:ENSG00000250208 +440125 HNRNPA1P30 HGNC:HGNC:39548 +440131 LINC00544 HGNC:HGNC:43679 +440132 LINC00545 HGNC:HGNC:43680|Ensembl:ENSG00000236094 +440138 ALG11 MIM:613666|HGNC:HGNC:32456|Ensembl:ENSG00000253710|Vega:OTTHUMG00000016959 +440142 TARDBPP2 HGNC:HGNC:39848 +440145 MZT1 MIM:613448|HGNC:HGNC:33830|Ensembl:ENSG00000204899|Vega:OTTHUMG00000017069 +440153 OR11H12 HGNC:HGNC:30738|Ensembl:ENSG00000257115|Vega:OTTHUMG00000170298 +440159 OR11H13P HGNC:HGNC:29997 +440163 RNASE13 HGNC:HGNC:25285|Ensembl:ENSG00000206150|Vega:OTTHUMG00000171110 +440173 LOC440173 Ensembl:ENSG00000269994 +440176 RPL12P6 HGNC:HGNC:23538 +440180 LOC440180 - +440181 LOC440181 - +440184 CCDC196 HGNC:HGNC:20100|Ensembl:ENSG00000196553|Vega:OTTHUMG00000029779 +440193 CCDC88C MIM:611204|HGNC:HGNC:19967|Ensembl:ENSG00000015133|Vega:OTTHUMG00000171099 +440224 CXADRP3 HGNC:HGNC:33974|Ensembl:ENSG00000265766 +440225 NF1P2 HGNC:HGNC:38664 +440243 GOLGA6L22 HGNC:HGNC:50289 +440248 HERC2P9 HGNC:HGNC:30495|Ensembl:ENSG00000206149 +440253 WHAMMP2 HGNC:HGNC:32360 +440270 GOLGA8B MIM:609619|HGNC:HGNC:31973|Ensembl:ENSG00000215252|Vega:OTTHUMG00000129549 +440275 EIF2AK4 MIM:609280|HGNC:HGNC:19687|Ensembl:ENSG00000128829|Vega:OTTHUMG00000172403 +440278 CATSPER2P1 HGNC:HGNC:31054|Ensembl:ENSG00000205771 +440279 UNC13C MIM:614568|HGNC:HGNC:23149|Ensembl:ENSG00000137766|Vega:OTTHUMG00000172542 +440288 UBL7-AS1 HGNC:HGNC:48614|Ensembl:ENSG00000247240 +440292 LOC440292 - +440293 DNM1DN11-7 - +440295 GOLGA6L9 HGNC:HGNC:37229|Ensembl:ENSG00000197978|Vega:OTTHUMG00000170547 +440299 DNM1P41 HGNC:HGNC:35191 +440300 LOC440300 - +440303 DNM1P44 HGNC:HGNC:35194 +440307 TTLL13P HGNC:HGNC:32484|Ensembl:ENSG00000213471 +440311 LOC440311 Ensembl:ENSG00000260521 +440313 LOC440313 - +440335 SMIM22 HGNC:HGNC:48329|Ensembl:ENSG00000267795|Vega:OTTHUMG00000177849 +440345 NPIPB4 HGNC:HGNC:41985|Ensembl:ENSG00000185864 +440346 LOC440346 - +440348 NPIPB15 HGNC:HGNC:34409|Ensembl:ENSG00000196436|Vega:OTTHUMG00000156916 +440350 NPIPB7 HGNC:HGNC:33832 +440352 SNX29P2 HGNC:HGNC:31914 +440353 NPIPB12 HGNC:HGNC:37491 +440354 SMG1P2 HGNC:HGNC:49859 +440356 CDIPT-AS1 HGNC:HGNC:48609|Ensembl:ENSG00000214725 +440359 YBX3P1 HGNC:HGNC:2429 +440366 HERC2P8 HGNC:HGNC:38747 +440375 RAB43P1 HGNC:HGNC:33153 +440386 LOC440386 Ensembl:ENSG00000261079 +440387 CTRB2 HGNC:HGNC:2522|Ensembl:ENSG00000168928|Vega:OTTHUMG00000159271 +440390 LINC02181 HGNC:HGNC:53043|Ensembl:ENSG00000232190 +440396 HNRNPA1P16 HGNC:HGNC:39134 +440400 RNASEK MIM:617098|HGNC:HGNC:33911|Ensembl:ENSG00000219200|Vega:OTTHUMG00000170145 +440406 UBE2SP2 HGNC:HGNC:32196 +440416 CCDC144NL-AS1 HGNC:HGNC:51340|Ensembl:ENSG00000233098 +440419 TBC1D3P5 HGNC:HGNC:43567|Ensembl:ENSG00000266433 +440423 SUZ12P1 HGNC:HGNC:32421 +440434 LOC440434 Ensembl:ENSG00000274487 +440435 GPR179 MIM:614515|HGNC:HGNC:31371|Ensembl:ENSG00000277399|Vega:OTTHUMG00000188545 +440446 LINC02072 HGNC:HGNC:52918|Ensembl:ENSG00000225860 +440447 RPS2P27 HGNC:HGNC:36876 +440452 TBC1D3P2 HGNC:HGNC:27783|Ensembl:ENSG00000188755 +440456 PLEKHM1P1 HGNC:HGNC:35411 +440459 SLC16A6P1 HGNC:HGNC:48932 +440461 LOC440461 - +440465 BAIAP2-AS1 HGNC:HGNC:44342|Ensembl:ENSG00000226137 +440482 ANKRD20A5P HGNC:HGNC:33833 +440487 RPL21P128 HGNC:HGNC:36311 +440489 LOC440489 - +440498 HSBP1L1 HGNC:HGNC:37243|Ensembl:ENSG00000226742|Vega:OTTHUMG00000180375 +440503 PLIN5 MIM:613248|HGNC:HGNC:33196|Ensembl:ENSG00000214456|Vega:OTTHUMG00000182008 +440508 CLEC4GP1 HGNC:HGNC:33502 +440514 LOC440514 - +440515 ZNF506 HGNC:HGNC:23780|Ensembl:ENSG00000081665|Vega:OTTHUMG00000182367 +440518 GOLGA2P9 HGNC:HGNC:49921|Ensembl:ENSG00000269332 +440519 ZNF724 HGNC:HGNC:32460 +440525 PRR13P5 HGNC:HGNC:50618 +440533 PSG8 MIM:176397|HGNC:HGNC:9525|Ensembl:ENSG00000124467|Vega:OTTHUMG00000151118 +440556 LINC00982 HGNC:HGNC:48664|Ensembl:ENSG00000177133 +440560 PRAMEF11 HGNC:HGNC:14086|Ensembl:ENSG00000239810|Vega:OTTHUMG00000001929 +440561 PRAMEF6 HGNC:HGNC:30583|Ensembl:ENSG00000232423|Vega:OTTHUMG00000001984 +440563 HNRNPCL2 HGNC:HGNC:48813|Ensembl:ENSG00000275774|Vega:OTTHUMG00000009503 +440567 UQCRHL HGNC:HGNC:51714|Ensembl:ENSG00000233954|Vega:OTTHUMG00000003109 +440568 LOC440568 - +440570 LOC440570 - +440574 MINOS1 MIM:616574|HGNC:HGNC:32068|Ensembl:ENSG00000173436|Ensembl:ENSG00000270136|Vega:OTTHUMG00000002712|Vega:OTTHUMG00000183956 +440575 RPL21P29 HGNC:HGNC:35793 +440577 NPM1P39 HGNC:HGNC:45218 +440584 SLC2A1-AS1 HGNC:HGNC:44187|Ensembl:ENSG00000227533 +440585 FAM183A HGNC:HGNC:34347|Ensembl:ENSG00000186973|Vega:OTTHUMG00000007286 +440587 RPL6P1 HGNC:HGNC:35972 +440589 RPS2P8 HGNC:HGNC:36207 +440590 ZYG11A HGNC:HGNC:32058|Ensembl:ENSG00000203995|Vega:OTTHUMG00000008923 +440594 LINC01761 HGNC:HGNC:52551|Ensembl:ENSG00000233907 +440595 EEF1A1P11 HGNC:HGNC:3206 +440600 LOC440600 Ensembl:ENSG00000227963 +440602 CYMP-AS1 HGNC:HGNC:52509|Ensembl:ENSG00000235407 +440603 BCL2L15 HGNC:HGNC:33624|Ensembl:ENSG00000188761|Vega:OTTHUMG00000011940 +440606 HSD3BP2 HGNC:HGNC:5220 +440672 NUDT4P1 HGNC:HGNC:18012 +440686 HIST2H3PS2 HGNC:HGNC:32060 +440689 HIST2H2BF HGNC:HGNC:24700|Ensembl:ENSG00000203814|Vega:OTTHUMG00000183159 +440695 ETV3L HGNC:HGNC:33834|Ensembl:ENSG00000253831|Vega:OTTHUMG00000041325 +440699 LRRC52 MIM:615218|HGNC:HGNC:32156|Ensembl:ENSG00000162763|Vega:OTTHUMG00000034625 +440700 LOC440700 Ensembl:ENSG00000215838 +440704 LINC01720 HGNC:HGNC:52507|Ensembl:ENSG00000231175 +440712 C1orf186 MIM:616088|HGNC:HGNC:25341|Ensembl:ENSG00000263961|Vega:OTTHUMG00000184376 +440714 C1orf143 HGNC:HGNC:32045 +440730 TRIM67 MIM:610584|HGNC:HGNC:31859|Ensembl:ENSG00000119283|Vega:OTTHUMG00000037958 +440732 RPS7P3 HGNC:HGNC:36518 +440737 RPL35P1 HGNC:HGNC:36695 +440738 MAP1LC3C MIM:609605|HGNC:HGNC:13353|Ensembl:ENSG00000197769|Vega:OTTHUMG00000039865 +440742 LOC440742 Ensembl:ENSG00000279774 +440757 LINC00851 HGNC:HGNC:43424|Ensembl:ENSG00000237282 +440786 LOC440786 - +440792 LOC440792 - +440795 CA15P2 HGNC:HGNC:14916 +440799 P2RX6P HGNC:HGNC:34076 +440804 RIMBP3B MIM:612700|HGNC:HGNC:33891|Ensembl:ENSG00000274600|Vega:OTTHUMG00000150819 +440822 PIWIL3 MIM:610314|HGNC:HGNC:18443|Ensembl:ENSG00000184571|Vega:OTTHUMG00000150788 +440823 MIAT MIM:611082|HGNC:HGNC:33425|Ensembl:ENSG00000225783 +440829 SHISA8 MIM:617329|HGNC:HGNC:18351|Ensembl:ENSG00000234965 +440836 ODF3B HGNC:HGNC:34388|Ensembl:ENSG00000177989|Vega:OTTHUMG00000150334 +440854 CAPN14 MIM:610229|HGNC:HGNC:16664|Ensembl:ENSG00000214711|Vega:OTTHUMG00000152039 +440864 LOC440864 - +440888 ACTR3BP2 HGNC:HGNC:38677 +440894 LINC01123 HGNC:HGNC:49269|Ensembl:ENSG00000204588 +440895 LOC440895 Ensembl:ENSG00000186148 +440896 LOC440896 - +440900 LINC01191 HGNC:HGNC:49595|Ensembl:ENSG00000234199 +440902 NPM1P32 HGNC:HGNC:45211 +440905 FAR2P1 HGNC:HGNC:49284|Ensembl:ENSG00000180178 +440910 LOC440910 Ensembl:ENSG00000231431 +440915 POTEKP MIM:611266|HGNC:HGNC:30182 +440917 YWHAEP5 HGNC:HGNC:49439 +440918 FLJ46875 - +440925 LINC01124 HGNC:HGNC:49270|Ensembl:ENSG00000222033 +440926 H3F3AP4 HGNC:HGNC:42980 +440934 LOC440934 Ensembl:ENSG00000237732 +440944 THUMPD3-AS1 HGNC:HGNC:44478|Ensembl:ENSG00000206573 +440952 EIF1B-AS1 HGNC:HGNC:44555|Ensembl:ENSG00000280739 +440955 TMEM89 HGNC:HGNC:32372|Ensembl:ENSG00000183396|Vega:OTTHUMG00000156647 +440956 IQCF6 HGNC:HGNC:35158|Ensembl:ENSG00000214686|Vega:OTTHUMG00000187148 +440957 SMIM4 HGNC:HGNC:37257|Ensembl:ENSG00000168273|Vega:OTTHUMG00000158726 +440970 LINC00971 HGNC:HGNC:48737|Ensembl:ENSG00000242641 +440973 LOC440973 - +440982 LOC440982 - +440991 RPS3P3 HGNC:HGNC:36700 +440992 RPS20P14 HGNC:HGNC:36692 +440993 LINC00969 HGNC:HGNC:48729 +441009 CPEB2-AS1 HGNC:HGNC:49082|Ensembl:ENSG00000247624 +441013 RPS2P21 HGNC:HGNC:35591 +441024 MTHFD2L MIM:614047|HGNC:HGNC:31865|Ensembl:ENSG00000163738|Vega:OTTHUMG00000157135 +441025 LINC02483 HGNC:HGNC:53457|Ensembl:ENSG00000251383 +441026 HNRNPA3P13 HGNC:HGNC:48759 +441027 TMEM150C MIM:617292|HGNC:HGNC:37263|Ensembl:ENSG00000249242|Vega:OTTHUMG00000161083 +441032 EEF1A1P9 HGNC:HGNC:3204 +441034 RPL7AP30 HGNC:HGNC:35757 +441046 GUSBP5 HGNC:HGNC:42319|Ensembl:ENSG00000236296 +441050 PTGES3P3 HGNC:HGNC:43823 +441051 HSP90AA6P HGNC:HGNC:32536 +441052 LOC441052 - +441054 C4orf47 HGNC:HGNC:34346|Ensembl:ENSG00000205129|Vega:OTTHUMG00000160458 +441056 DUX4L4 HGNC:HGNC:38686 +441058 LINC01667 HGNC:HGNC:52455 +441061 MARCH11 MIM:613338|HGNC:HGNC:33609|Ensembl:ENSG00000183654|Vega:OTTHUMG00000161789 +441066 GUSBP8 HGNC:HGNC:42322 +441072 FLJ31104 Ensembl:ENSG00000227908 +441073 RPL26P19 HGNC:HGNC:36393 +441081 LOC441081 - +441086 LOC441086 - +441087 LOC441087 - +441089 CRSP8P - +441094 NR2F1-AS1 HGNC:HGNC:48622|Ensembl:ENSG00000237187 +441098 LOC441098 - +441108 C5orf56 HGNC:HGNC:33838|Ensembl:ENSG00000197536|Vega:OTTHUMG00000059493 +441114 RPLP0P9 - +441116 LINC01951 HGNC:HGNC:52774|Ensembl:ENSG00000204754 +441123 LINC00266-3 HGNC:HGNC:21112 +441124 GTF2IP20 HGNC:HGNC:51732 +441131 ARPC3P5 HGNC:HGNC:39435 +441132 IMPDH1P9 HGNC:HGNC:33964 +441133 KRT18P38 HGNC:HGNC:33407 +441150 C6orf226 HGNC:HGNC:34431|Ensembl:ENSG00000221821|Vega:OTTHUMG00000156926 +441151 TMEM151B HGNC:HGNC:21315|Ensembl:ENSG00000178233|Vega:OTTHUMG00000014765 +441154 RPL7AP34 HGNC:HGNC:36778 +441155 LOC441155 - +441160 KRT19P1 HGNC:HGNC:33422 +441161 OOEP MIM:611689|HGNC:HGNC:21382|Ensembl:ENSG00000203907|Vega:OTTHUMG00000150057 +441166 CNN2P9 HGNC:HGNC:39534 +441168 FAM26F MIM:617305|HGNC:HGNC:33391|Ensembl:ENSG00000188820|Vega:OTTHUMG00000015438 +441172 FLJ46906 - +441177 LINC00602 HGNC:HGNC:43917|Ensembl:ENSG00000281832 +441178 LINC02487 HGNC:HGNC:53466|Ensembl:ENSG00000203688 +441179 LOC441179 - +441191 RNF216P1 HGNC:HGNC:33610|Ensembl:ENSG00000196204 +441194 PMS2CL HGNC:HGNC:30061|Ensembl:ENSG00000187953 +441204 LOC441204 - +441208 ZNRF2P1 HGNC:HGNC:42792 +441212 RP9P HGNC:HGNC:33969|Ensembl:ENSG00000205763 +441218 KRT8P20 HGNC:HGNC:33372 +441228 LOC441228 - +441234 ZNF716 HGNC:HGNC:32458|Ensembl:ENSG00000182111|Vega:OTTHUMG00000156689 +441238 NMD3P1 HGNC:HGNC:22672 +441239 LOC441239 - +441241 LOC441241 - +441242 LOC441242 Ensembl:ENSG00000272693 +441246 RPL35P5 HGNC:HGNC:36955 +441250 TYW1B HGNC:HGNC:33908|Ensembl:ENSG00000277149|Vega:OTTHUMG00000157067 +441251 SPDYE7P HGNC:HGNC:35466|Ensembl:ENSG00000179994 +441259 LOC441259 - +441261 FDPSP7 HGNC:HGNC:33487 +441263 DTX2P1-UPK3BP1-PMS2P11 HGNC:HGNC:42360|Ensembl:ENSG00000265479 +441272 SPDYE3 HGNC:HGNC:35462|Ensembl:ENSG00000214300|Vega:OTTHUMG00000155462 +441273 SPDYE2 HGNC:HGNC:33841|Ensembl:ENSG00000205238|Vega:OTTHUMG00000150385 +441282 AKR1B15 MIM:616336|HGNC:HGNC:37281|Ensembl:ENSG00000227471|Vega:OTTHUMG00000155376 +441294 CTAGE15 HGNC:HGNC:37295|Ensembl:ENSG00000271079|Vega:OTTHUMG00000153233 +441295 OR2A9P HGNC:HGNC:8236 +441307 HRAT92 Ensembl:ENSG00000223855 +441308 OR4F21 HGNC:HGNC:19583|Ensembl:ENSG00000176269|Vega:OTTHUMG00000163908 +441313 FAM90A4P HGNC:HGNC:32252 +441314 FAM90A13P MIM:613049|HGNC:HGNC:32261 +441315 FAM90A5P MIM:613043|HGNC:HGNC:32253 +441317 FAM90A7P MIM:613044|HGNC:HGNC:32255 +441320 LOC441320 - +441323 FAM90A16P HGNC:HGNC:32264 +441324 FAM90A8P MIM:613045|HGNC:HGNC:32256 +441326 FAM90A18P MIM:613052|HGNC:HGNC:32266 +441327 FAM90A9P MIM:613046|HGNC:HGNC:32257 +441328 FAM90A10P MIM:613047|HGNC:HGNC:32258 +441331 FAM90A11P HGNC:HGNC:32259 +441332 FAM90A24P HGNC:HGNC:32272 +441355 MIR2052HG HGNC:HGNC:51555|Ensembl:ENSG00000254349 +441359 REXO1L3P HGNC:HGNC:32240 +441362 REXO1L6P HGNC:HGNC:32243 +441369 FLJ46284 Ensembl:ENSG00000248858 +441374 FLJ42969 Ensembl:ENSG00000248599 +441376 AARD HGNC:HGNC:33842|Ensembl:ENSG00000205002|Vega:OTTHUMG00000164961 +441377 RPS26P35 HGNC:HGNC:36229 +441381 LRRC24 HGNC:HGNC:28947|Ensembl:ENSG00000254402|Vega:OTTHUMG00000165180 +441386 RPS26P3 HGNC:HGNC:23411 +441389 LINC01239 HGNC:HGNC:49796|Ensembl:ENSG00000234840 +441391 RBMXP2 HGNC:HGNC:23284 +441394 SUGT1P1 HGNC:HGNC:19384 +441400 RAB1C HGNC:HGNC:23683 +441410 FKBP4P7 HGNC:HGNC:50376 +441416 ADGRF5P2 HGNC:HGNC:32921 +441420 MYO5BP1 HGNC:HGNC:38495 +441425 ANKRD20A3 HGNC:HGNC:31981|Ensembl:ENSG00000276203|Vega:OTTHUMG00000188432 +441426 LINC00268 HGNC:HGNC:38543 +441430 ANKRD20A2 HGNC:HGNC:31979|Ensembl:ENSG00000183148|Vega:OTTHUMG00000058641 +441432 AQP7P3 HGNC:HGNC:31976 +441440 RPL7AP46 HGNC:HGNC:35698 +441442 MYO5BP3 HGNC:HGNC:38497 +441452 SPATA31C1 HGNC:HGNC:27846 +441454 LOC441454 - +441455 LOC441455 - +441457 NUTM2G HGNC:HGNC:23449|Ensembl:ENSG00000188152|Vega:OTTHUMG00000020305 +441459 ANKRD18B HGNC:HGNC:23644|Ensembl:ENSG00000230453|Vega:OTTHUMG00000019776 +441461 STX17-AS1 HGNC:HGNC:51174|Ensembl:ENSG00000255145 +441476 STPG3 HGNC:HGNC:37285|Ensembl:ENSG00000197768|Vega:OTTHUMG00000187404 +441478 NRARP HGNC:HGNC:33843|Ensembl:ENSG00000198435|Vega:OTTHUMG00000156150 +441481 GPX1P1 HGNC:HGNC:4560 +441484 HAUS1P2 HGNC:HGNC:43761 +441487 LOC441487 - +441488 LOC441488 - +441490 FTH1P18 HGNC:HGNC:3988 +441495 CENPVL2 HGNC:HGNC:43879|Ensembl:ENSG00000283093|Vega:OTTHUMG00000191517 +441501 LINC00891 HGNC:HGNC:48577 +441502 RPS26P11 HGNC:HGNC:31817 +441505 STIP1P3 HGNC:HGNC:49554 +441509 GLRA4 HGNC:HGNC:31715|Ensembl:ENSG00000188828|Vega:OTTHUMG00000022110 +441511 LOC441511 - +441518 RTL8B HGNC:HGNC:33156|Ensembl:ENSG00000212747|Vega:OTTHUMG00000022464 +441519 CT45A3 MIM:300794|HGNC:HGNC:33268|Ensembl:ENSG00000269096|Vega:OTTHUMG00000022489 +441521 CT45A5 MIM:300796|HGNC:HGNC:33270|Ensembl:ENSG00000228836|Vega:OTTHUMG00000188603 +441525 SPANXN4 MIM:300667|HGNC:HGNC:33177|Ensembl:ENSG00000189326|Vega:OTTHUMG00000022575 +441531 PGAM4 MIM:300567|HGNC:HGNC:21731|Ensembl:ENSG00000226784|Vega:OTTHUMG00000057865 +441533 RPL26P37 HGNC:HGNC:36004 +441543 TTTY6B HGNC:HGNC:31887|Ensembl:ENSG00000131548 +441548 BTBD7P1 HGNC:HGNC:44875 +441549 CDNF MIM:611233|HGNC:HGNC:24913|Ensembl:ENSG00000185267|Vega:OTTHUMG00000017713 +441550 RPS4XP11 HGNC:HGNC:37013 +441554 DUSP8P3 HGNC:HGNC:3077 +441572 GAPDHP28 HGNC:HGNC:37780 +441581 FRG2B HGNC:HGNC:33518|Ensembl:ENSG00000225899|Vega:OTTHUMG00000019328 +441584 SSU72P4 HGNC:HGNC:43623 +441592 LOC441592 - +441601 LOC441601 Ensembl:ENSG00000255042 +441608 OR5B3 HGNC:HGNC:8324|Ensembl:ENSG00000172769|Vega:OTTHUMG00000167516 +441609 YWHAZP9 HGNC:HGNC:39030 +441623 FTLP7 HGNC:HGNC:37955 +441630 BRI3P2 HGNC:HGNC:32543 +441631 TSPAN11 HGNC:HGNC:30795|Ensembl:ENSG00000110900|Vega:OTTHUMG00000168484 +441632 RPL13AP22 HGNC:HGNC:35825 +441639 OR9K2 HGNC:HGNC:15339|Ensembl:ENSG00000170605|Vega:OTTHUMG00000169827 +441641 RPL13AP23 HGNC:HGNC:36498 +441642 RPL7AP9 HGNC:HGNC:32398 +441644 LOC441644 - +441654 SMPD4P2 HGNC:HGNC:39674 +441662 TET1P1 HGNC:HGNC:33586 +441666 LOC441666 Ensembl:ENSG00000215146 +441669 OR4Q3 HGNC:HGNC:15426|Ensembl:ENSG00000182652|Vega:OTTHUMG00000170612 +441670 OR4M1 HGNC:HGNC:14735|Ensembl:ENSG00000176299|Vega:OTTHUMG00000170599 +441687 TEX21P HGNC:HGNC:35455 +441711 LOC441711 - +441722 LOC441722 - +441726 RPL28P4 HGNC:HGNC:36618 +441727 RPL36AP45 HGNC:HGNC:36032 +441728 LOC441728 - +441733 PRKXP1 HGNC:HGNC:9442 +441736 GOLGA8VP HGNC:HGNC:49920 +441744 RPS16P7 HGNC:HGNC:36505 +441750 LOC441750 - +441768 LOC441768 - +441771 MT1CP HGNC:HGNC:7395 +441774 RPS4Y1P1 HGNC:HGNC:36893 +441775 RPL18P13 HGNC:HGNC:35599 +441781 RPL23AP76 HGNC:HGNC:36555 +441783 ACTG1P24 HGNC:HGNC:49661 +441784 LOC441784 - +441795 HMGB3P27 HGNC:HGNC:39319 +441806 LOC441806 - +441818 WBP11P1 HGNC:HGNC:26250|Ensembl:ENSG00000260389 +441843 ZNF209P HGNC:HGNC:13000 +441849 MSRB1P1 HGNC:HGNC:43985 +441862 LOC441862 - +441864 TARM1 MIM:616802|HGNC:HGNC:37250|Ensembl:ENSG00000248385|Vega:OTTHUMG00000064912 +441869 ANKRD65 HGNC:HGNC:42950|Ensembl:ENSG00000235098|Vega:OTTHUMG00000002911 +441870 PRAMEF30P HGNC:HGNC:51892 +441871 PRAMEF7 HGNC:HGNC:28415|Ensembl:ENSG00000204510 +441873 PRAMEF25 HGNC:HGNC:49179|Ensembl:ENSG00000229571 +441876 RPS16P1 HGNC:HGNC:36462 +441878 RPS4XP4 HGNC:HGNC:36545 +441880 LOC441880 - +441884 CALR4P HGNC:HGNC:35456 +441887 LOC441887 - +441891 WDR82P2 HGNC:HGNC:33513 +441893 GAPDHP29 HGNC:HGNC:37781 +441896 RPL7P8 HGNC:HGNC:35914 +441897 PGCP1 HGNC:HGNC:39503|Ensembl:ENSG00000227179 +441898 RPS15AP9 HGNC:HGNC:36164 +441899 VPS25P1 HGNC:HGNC:44250 +441900 HSD3BP3 HGNC:HGNC:5221 +441904 LOC441904 - +441907 LOC441907 - +441908 NBPF18P HGNC:HGNC:31998 +441911 OR10J3 HGNC:HGNC:14992|Ensembl:ENSG00000196266|Vega:OTTHUMG00000037233 +441914 LOC441914 - +441915 SLC25A38P1 HGNC:HGNC:43858 +441925 BECN2 MIM:615687|HGNC:HGNC:38606|Ensembl:ENSG00000196289|Vega:OTTHUMG00000039863 +441931 VN1R17P HGNC:HGNC:37331 +441932 OR2W5 HGNC:HGNC:15424 +441933 OR13G1 MIM:611677|HGNC:HGNC:14999|Ensembl:ENSG00000197437|Vega:OTTHUMG00000040212 +441940 LIN28AP3 HGNC:HGNC:38057 +441951 ZFAS1 HGNC:HGNC:33101|Ensembl:ENSG00000177410 +441957 FEM1AP1 HGNC:HGNC:17219 +441958 GXYLT1P2 HGNC:HGNC:39677 +441996 LOC441996 - +442006 NPM1P48 HGNC:HGNC:45227 +442013 LDHAP3 HGNC:HGNC:6538 +442017 LOC442017 - +442028 LOC442028 Ensembl:ENSG00000259848 +442038 SULT1C3 MIM:617151|HGNC:HGNC:33543|Ensembl:ENSG00000196228|Vega:OTTHUMG00000153227 +442041 LOC442041 - +442042 LOC442042 - +442058 LOC442058 - +442060 SAP18P2 HGNC:HGNC:51568 +442063 LOC442063 - +442064 LOC442064 - +442075 EMC3-AS1 HGNC:HGNC:49223 +442078 KRT8P18 HGNC:HGNC:33370 +442083 HSP90AB5P HGNC:HGNC:32539 +442086 RPL10P7 HGNC:HGNC:35974 +442087 LOC442087 - +442097 ACTG1P23 HGNC:HGNC:51503 +442098 MTHFD2P7 HGNC:HGNC:48865 +442101 OR7E162P HGNC:HGNC:28374 +442104 OR7E86P HGNC:HGNC:14694 +442105 OR7E85P HGNC:HGNC:14692 +442108 RPL22P13 HGNC:HGNC:36352 +442112 SERBP1P5 HGNC:HGNC:44632 +442113 LOC442113 - +442114 KRT19P3 HGNC:HGNC:33424 +442117 GALNTL6 MIM:615138|HGNC:HGNC:33844|Ensembl:ENSG00000174473|Vega:OTTHUMG00000160807 +442131 ALG3P1 HGNC:HGNC:45159 +442132 LOC442132 - +442142 SOX30P1 HGNC:HGNC:35122 +442153 PSMC1P11 HGNC:HGNC:39786 +442155 LOC442155 - +442156 PKMP5 HGNC:HGNC:44247 +442157 HNRNPLP1 HGNC:HGNC:48748 +442158 RPS26P29 HGNC:HGNC:36456 +442160 RPL21P62 HGNC:HGNC:36843 +442161 LOC442161 - +442162 RPS4XP7 HGNC:HGNC:36885 +442164 DDX18P3 HGNC:HGNC:33966 +442167 ASS1P1 HGNC:HGNC:759 +442171 RPL10P2 HGNC:HGNC:13975 +442172 LOC442172 - +442175 RPLP2P1 HGNC:HGNC:18724 +442179 OR1F12 HGNC:HGNC:13964 +442181 RPSAP2 HGNC:HGNC:18771 +442183 OR2P1P HGNC:HGNC:8272 +442184 OR2B3 HGNC:HGNC:8238|Ensembl:ENSG00000204703|Vega:OTTHUMG00000031226 +442185 OR2J1 HGNC:HGNC:8259|Vega:OTTHUMG00000031280 +442186 OR2J3 MIM:615016|HGNC:HGNC:8261|Ensembl:ENSG00000204701|Vega:OTTHUMG00000031092 +442188 OR2J4P HGNC:HGNC:8262 +442189 OR2H4P HGNC:HGNC:8255 +442190 OR2B4P HGNC:HGNC:8239 +442191 OR14J1 HGNC:HGNC:13971|Ensembl:ENSG00000204695|Vega:OTTHUMG00000031184 +442192 DDX6P1 HGNC:HGNC:13948 +442194 OR10C1 HGNC:HGNC:8165|Ensembl:ENSG00000206474|Vega:OTTHUMG00000031207 +442195 RPS17P1 HGNC:HGNC:13982 +442197 OR2I1P HGNC:HGNC:8258 +442204 MYL8P HGNC:HGNC:7589 +442205 KRT18P9 HGNC:HGNC:17767 +442206 GPR166P HGNC:HGNC:23626 +442210 TUBBP9 HGNC:HGNC:42178 +442211 ATP6V0CP3 HGNC:HGNC:40001 +442213 PTCHD4 MIM:616908|HGNC:HGNC:21345|Ensembl:ENSG00000244694|Vega:OTTHUMG00000150404 +442215 EEF1A1P42 HGNC:HGNC:48927 +442216 RPS17P5 HGNC:HGNC:21352 +442217 RPL31P28 HGNC:HGNC:36253 +442218 RPL31P33 HGNC:HGNC:36886 +442221 RCC2P7 HGNC:HGNC:42383 +442225 LOC442225 - +442227 EEF1B2P5 HGNC:HGNC:32476 +442229 SLC25A51P1 HGNC:HGNC:23325 +442231 GAPDHP63 HGNC:HGNC:4157 +442232 RPL17P25 HGNC:HGNC:36844 +442233 SMARCE1P2 HGNC:HGNC:39732 +442234 RCN1P1 HGNC:HGNC:39205 +442236 KRT18P50 HGNC:HGNC:33420 +442237 RPS7P8 HGNC:HGNC:35710 +442239 PRDX2P4 HGNC:HGNC:44969 +442240 ZNF259P1 HGNC:HGNC:13052 +442242 RPL7P28 HGNC:HGNC:35899 +442244 LOC442244 - +442245 GSTM2P1 HGNC:HGNC:38009 +442247 RFPL4B HGNC:HGNC:33264|Ensembl:ENSG00000251258|Vega:OTTHUMG00000015390 +442249 KRT18P65 HGNC:HGNC:48892 +442252 KRT18P22 HGNC:HGNC:33390 +442253 NEPNP HGNC:HGNC:33184 +442255 SLC25A5P7 HGNC:HGNC:513 +442256 PPP1R14BP5 HGNC:HGNC:16332 +442257 RPS4XP9 HGNC:HGNC:35792 +442258 EEF1DP5 HGNC:HGNC:33524 +442260 RPL23AP46 HGNC:HGNC:35894 +442262 GAPDHP73 HGNC:HGNC:22956 +442263 LOC442263 - +442266 YAP1P1 HGNC:HGNC:38016 +442267 CCT7P1 HGNC:HGNC:35149 +442270 RPS12P11 HGNC:HGNC:36042 +442271 TUBB4BP7 HGNC:HGNC:42337 +442272 LOC442272 - +442290 NHP2P2 HGNC:HGNC:22797 +442291 PSMC1P2 HGNC:HGNC:39777 +442292 LOC442292 - +442293 LOC442293 - +442304 FTLP15 HGNC:HGNC:37965 +442308 TUBBP6 HGNC:HGNC:42175 +442309 LOC442309 - +442317 SAPCD2P2 HGNC:HGNC:51278 +442318 SAPCD2P4 HGNC:HGNC:51280 +442319 ZNF727 HGNC:HGNC:22785|Ensembl:ENSG00000214652|Vega:OTTHUMG00000156536 +442320 SAPCD2P1 HGNC:HGNC:51277 +442325 EEF1DP4 HGNC:HGNC:22598 +442326 RPL31P38 HGNC:HGNC:36834 +442334 ARF1P1 HGNC:HGNC:22500 +442338 IRS3P HGNC:HGNC:6127 +442361 OR2A2 HGNC:HGNC:8230|Ensembl:ENSG00000221989|Vega:OTTHUMG00000158001 +442382 LOC442382 - +442384 VENTXP5 HGNC:HGNC:32214 +442388 SDR16C6P HGNC:HGNC:35413|Ensembl:ENSG00000253542 +442389 LOC442389 - +442396 ARF1P3 HGNC:HGNC:39884 +442405 KRT18P66 HGNC:HGNC:48893 +442406 KRT18P36 HGNC:HGNC:33405 +442415 ATP5A1P7 HGNC:HGNC:37665 +442416 ATP5A1P5 HGNC:HGNC:825 +442421 PTGER4P2-CDK2AP2P2 HGNC:HGNC:44749 +442425 FOXB2 HGNC:HGNC:23315|Ensembl:ENSG00000204612|Vega:OTTHUMG00000020051 +442426 RPS2P34 HGNC:HGNC:36370 +442427 LOC442427 - +442429 EEF1DP2 HGNC:HGNC:33523 +442442 RPL14P5 HGNC:HGNC:37720 +442443 LOC442443 - +442444 FAM47C HGNC:HGNC:25301|Ensembl:ENSG00000198173|Vega:OTTHUMG00000024025 +442445 LOC442445 - +442446 UBTFL11 HGNC:HGNC:50288 +442447 CLIC4P3 HGNC:HGNC:49799 +442454 UQCRBP1 HGNC:HGNC:12583 +442455 KRT8P27 HGNC:HGNC:33379 +442459 XRCC6P5 HGNC:HGNC:45187 +442460 LOC442460 - +442465 SAGE4P HGNC:HGNC:51339 +442479 HSFY3P HGNC:HGNC:37119 +442485 OFD1P16Y HGNC:HGNC:18213 +442486 ZNF736P1Y HGNC:HGNC:37726 +442497 LOC442497 Ensembl:ENSG00000249574 +442517 LOC442517 - +442523 DPY19L2P4 HGNC:HGNC:22176|Ensembl:ENSG00000235436 +442524 DPY19L2P3 HGNC:HGNC:22367|Ensembl:ENSG00000227855 +442525 SLC25A5P5 HGNC:HGNC:511 +442572 SPDYE21P HGNC:HGNC:51517 +442578 STAG3L3 HGNC:HGNC:33845 +442582 STAG3L2 HGNC:HGNC:33886 +442590 SPDYE5 HGNC:HGNC:35464|Ensembl:ENSG00000170092|Vega:OTTHUMG00000156138 +442603 LOC442603 - +442659 RPL23P7 HGNC:HGNC:36215 +442660 RPL7AP38 HGNC:HGNC:36161 +442661 HMGB3P20 HGNC:HGNC:39312 +442668 NECAP1P1 HGNC:HGNC:43912 +442673 TUBG1P HGNC:HGNC:12418 +442676 CICP8 HGNC:HGNC:37757 +442707 MTHFD2P5 HGNC:HGNC:48863 +442709 EEF1A1P28 HGNC:HGNC:37902 +442712 RPL7AP40 HGNC:HGNC:35883 +442713 LOC442713 - +442720 EIF3IP1 HGNC:HGNC:13277|Ensembl:ENSG00000237064 +442721 LMOD2 MIM:608006|HGNC:HGNC:6648|Ensembl:ENSG00000170807|Vega:OTTHUMG00000157149 +442723 RPL27P11 HGNC:HGNC:36533 +442726 RPS17P12 HGNC:HGNC:35930 +442727 LOC442727 - +442730 ST13P17 HGNC:HGNC:38859 +442775 RAC1P2 HGNC:HGNC:31414 +442777 TECRP1 HGNC:HGNC:44050 +442862 PRY2 MIM:400041|HGNC:HGNC:21504|Ensembl:ENSG00000169807|Vega:OTTHUMG00000043586 +442863 PRYP1 HGNC:HGNC:34018 +442864 PRYP2 HGNC:HGNC:34019 +442865 PRYP3 HGNC:HGNC:34020 +442866 PRYP4 HGNC:HGNC:34021 +442867 BPY2B HGNC:HGNC:25449|Ensembl:ENSG00000183795|Vega:OTTHUMG00000045101 +442868 BPY2C HGNC:HGNC:18225|Ensembl:ENSG00000185894|Vega:OTTHUMG00000045199 +442890 MIR133B MIM:610946|HGNC:HGNC:31759|Ensembl:ENSG00000199080|miRBase:MI0000822 +442891 MIR135B HGNC:HGNC:31760|Ensembl:ENSG00000199059|miRBase:MI0000810 +442892 MIR148B MIM:613787|HGNC:HGNC:31761|Ensembl:ENSG00000199122|miRBase:MI0000811 +442893 MIR151A HGNC:HGNC:31762|Ensembl:ENSG00000254324|miRBase:MI0000809 +442894 MIR302B MIM:614597|HGNC:HGNC:31763|Ensembl:ENSG00000284463|miRBase:MI0000772 +442895 MIR302C MIM:614598|HGNC:HGNC:31764|Ensembl:ENSG00000199102|miRBase:MI0000773 +442896 MIR302D MIM:614599|HGNC:HGNC:31765|Ensembl:ENSG00000199145|miRBase:MI0000774 +442897 MIR323A HGNC:HGNC:31766|Ensembl:ENSG00000199069|miRBase:MI0000807 +442898 MIR324 HGNC:HGNC:31767|Ensembl:ENSG00000199053|miRBase:MI0000813 +442899 MIR325 HGNC:HGNC:31768|Ensembl:ENSG00000207995|miRBase:MI0000824 +442900 MIR326 MIM:613755|HGNC:HGNC:31769|Ensembl:ENSG00000199090|miRBase:MI0000808 +442901 MIR328 MIM:613701|HGNC:HGNC:31770|Ensembl:ENSG00000207948|miRBase:MI0000804 +442902 MIR330 HGNC:HGNC:31771|Ensembl:ENSG00000284544|miRBase:MI0000803 +442903 MIR331 HGNC:HGNC:31772|Ensembl:ENSG00000199172|miRBase:MI0000812 +442904 MIR335 MIM:611768|HGNC:HGNC:31773|Ensembl:ENSG00000199043|miRBase:MI0000816 +442905 MIR337 HGNC:HGNC:31774|Ensembl:ENSG00000199151|miRBase:MI0000806 +442906 MIR338 MIM:614059|HGNC:HGNC:31775|Ensembl:ENSG00000283604|miRBase:MI0000814 +442907 MIR339 MIM:615977|HGNC:HGNC:31776|Ensembl:ENSG00000199023|miRBase:MI0000815 +442908 MIR340 HGNC:HGNC:31777|Ensembl:ENSG00000198995|miRBase:MI0000802 +442909 MIR342 HGNC:HGNC:31778|Ensembl:ENSG00000199082|miRBase:MI0000805 +442910 MIR345 HGNC:HGNC:31779|Ensembl:ENSG00000198984|miRBase:MI0000825 +442911 MIR346 MIM:611190|HGNC:HGNC:31780|Ensembl:ENSG00000199104|miRBase:MI0000826 +442912 MIR367 MIM:614600|HGNC:HGNC:31781|Ensembl:ENSG00000199169|miRBase:MI0000775 +442913 MIR376C MIM:610983|HGNC:HGNC:31782|Ensembl:ENSG00000283279|miRBase:MI0000776 +442914 MIR369 MIM:611794|HGNC:HGNC:31783|Ensembl:ENSG00000199025|miRBase:MI0000777 +442915 MIR370 MIM:612553|HGNC:HGNC:31784|Ensembl:ENSG00000199005|miRBase:MI0000778 +442916 MIR371A MIM:612043|HGNC:HGNC:31785|Ensembl:ENSG00000199031|miRBase:MI0000779 +442917 MIR372 MIM:612044|HGNC:HGNC:31786|Ensembl:ENSG00000199095|miRBase:MI0000780 +442918 MIR373 MIM:611954|HGNC:HGNC:31787|Ensembl:ENSG00000199143|miRBase:MI0000781 +442919 MIR374A HGNC:HGNC:31788|Ensembl:ENSG00000199168|miRBase:MI0000782 +442920 MIR196B MIM:609688|HGNC:HGNC:31790|Ensembl:ENSG00000283745|miRBase:MI0001150 +444882 IGFL4 MIM:610547|HGNC:HGNC:32931|Ensembl:ENSG00000204869|Vega:OTTHUMG00000182491 +444980 HYT4 MIM:608742 +445328 ARHGEF35 HGNC:HGNC:33846|Ensembl:ENSG00000213214|Vega:OTTHUMG00000158010 +445329 SULT1A4 MIM:615819|HGNC:HGNC:30004|Ensembl:ENSG00000213648|Vega:OTTHUMG00000170468 +445347 TARP MIM:609642 +445372 TRIM6-TRIM34 HGNC:HGNC:33440|Ensembl:ENSG00000258588|Vega:OTTHUMG00000066899 +445571 CBWD3 MIM:611080|HGNC:HGNC:18519|Ensembl:ENSG00000196873|Vega:OTTHUMG00000184383 +445573 ATP5J2P3 HGNC:HGNC:21286 +445577 C9orf129 HGNC:HGNC:31116|Ensembl:ENSG00000204352|Vega:OTTHUMG00000020248 +445582 POTEE MIM:608914|HGNC:HGNC:33895|Ensembl:ENSG00000188219|Vega:OTTHUMG00000186974 +445815 PALM2-AKAP2 HGNC:HGNC:33529|Ensembl:ENSG00000157654|Vega:OTTHUMG00000156812 +446207 ACTBP10 HGNC:HGNC:31819 +446209 RPS26P9 HGNC:HGNC:31821 +448831 FRG2 MIM:609032|HGNC:HGNC:19136|Ensembl:ENSG00000205097|Vega:OTTHUMG00000160339 +448834 KPRP MIM:613260|HGNC:HGNC:31823|Ensembl:ENSG00000203786|Vega:OTTHUMG00000012402 +448835 LCE6A HGNC:HGNC:31824|Ensembl:ENSG00000235942|Vega:OTTHUMG00000012448 +448962 DFNA54 MIM:615649|HGNC:HGNC:23566 +448963 DFNB51 MIM:609941|HGNC:HGNC:24367 +448990 TAS2R6P HGNC:HGNC:20616 +448991 TAS2R67P HGNC:HGNC:43898 +449013 ANIB2 MIM:608542|HGNC:HGNC:31941 +449015 ASPG3 MIM:608781 +449016 BMIQ5 MIM:608558|HGNC:HGNC:31117 +449017 BMIQ6 MIM:608559|HGNC:HGNC:22120 +449018 EJM3 MIM:608816 +449481 DFNB43 HGNC:HGNC:17480 +449483 DFNB45 MIM:612433|HGNC:HGNC:22400 +449488 DFNB46 MIM:609647|HGNC:HGNC:31085 +449489 DFNB47 MIM:609946|HGNC:HGNC:31086 +449491 DEFA8P HGNC:HGNC:31799|Ensembl:ENSG00000223629 +449492 DEFA9P HGNC:HGNC:31800|Ensembl:ENSG00000233238 +449493 DEFA10P HGNC:HGNC:31801 +449518 P2RY10P2 HGNC:HGNC:32924 +449520 GGNBP1 MIM:609495|HGNC:HGNC:19427|Ensembl:ENSG00000204188 +449619 ERVK-7 MIM:614013|HGNC:HGNC:31828 +449645 SF3A3P2 HGNC:HGNC:23277 +450086 AD9 MIM:608907 +450087 ADHD1 MIM:608903 +450088 ADHD2 MIM:608904 +450089 ADHD3 MIM:608905 +450090 ADHD4 MIM:608906 +450092 KTCN2 MIM:608932 +450093 LNCR1 MIM:608935 +450095 PLF MIM:608852 +450096 PAPA4 MIM:608562 +450097 RLS2 MIM:608831 +450208 LCEP1 HGNC:HGNC:31806 +450209 LCEP2 HGNC:HGNC:31807 +450210 LCEP4 HGNC:HGNC:31808 +450211 LCEP3 HGNC:HGNC:31809 +450232 PHF5CP HGNC:HGNC:32385 +450234 PHF5GP HGNC:HGNC:23269 +450238 PHF5DP HGNC:HGNC:23268 +450239 PHF5EP HGNC:HGNC:23267 +450246 PHF5FP HGNC:HGNC:23266 +450250 PHF5HP HGNC:HGNC:23264 +474148 TTTY3B HGNC:HGNC:31888|Ensembl:ENSG00000280961 +474149 TTTY4B HGNC:HGNC:31891|Ensembl:ENSG00000235412 +474150 TTTY4C HGNC:HGNC:31892|Ensembl:ENSG00000228296 +474151 TTTY17B HGNC:HGNC:31889|Ensembl:ENSG00000227439 +474152 TTTY17C HGNC:HGNC:31890|Ensembl:ENSG00000223641 +474159 DYX9 MIM:300509|HGNC:HGNC:16755 +474167 HDGFP1 HGNC:HGNC:31836 +474168 WG MIM:608710 +474170 LRRC37A2 MIM:616556|HGNC:HGNC:32404|Ensembl:ENSG00000238083|Vega:OTTHUMG00000178032 +474174 SGCEP - +474185 OA29 - +474186 OA30 - +474187 BP35 - +474188 OA24 - +474189 BP24 - +474190 BP30 - +474191 BP31 - +474192 BP32 - +474193 BP33 - +474194 BP34 - +474195 OA16 - +474196 OA25 - +474197 BP22 - +474198 BP23 - +474199 BP9 - +474200 BW22 - +474201 BP45 - +474202 BP46 - +474203 BP47 - +474204 BP48 - +474205 BP49 - +474206 BP51 - +474207 BP50 - +474208 BP52 - +474209 BP53 - +474210 BP54 - +474211 BP55 - +474212 BP17 - +474213 BP18 - +474214 BP19 - +474215 BP21 - +474216 BP20 - +474217 BP36 - +474218 BP37 - +474219 BP39 - +474220 BP38 - +474221 RA1 - +474222 RA2 - +474223 RA3 - +474224 RA4 - +474225 RA5 - +474226 RA6 - +474227 RA7 - +474228 RA8 - +474229 RA9 - +474230 RA10 - +474231 RA11 - +474232 RA12 - +474233 RA13 - +474234 RA14 - +474235 RA15 - +474236 RA16 - +474237 RA17 - +474238 RA31 - +474239 RA18 - +474240 RA19 - +474241 RA20 - +474242 RA21 - +474243 RA22 - +474244 RA23 - +474245 RA24 - +474246 RA25 - +474247 RA26 - +474248 RA27 - +474249 RA28 - +474250 RA29 - +474251 RA30 - +474252 BP10 - +474253 BP11 - +474254 BP12 - +474255 BP13 - +474256 BP1 - +474257 BP2 - +474258 BP4 - +474259 BP3 - +474260 BP14 - +474261 BP15 - +474262 BP16 - +474263 BW8 - +474264 BW9 - +474265 BW10 - +474266 BP25 - +474267 BP26 - +474268 BP28 - +474269 BP27 - +474270 BW2 - +474271 BW3 - +474272 BW4 - +474273 BW5 - +474274 BW7 - +474275 BW6 - +474276 BW23 - +474277 BW24 - +474278 BW25 - +474279 BW26 - +474280 BW27 - +474281 BW28 - +474282 BW29 - +474283 BW30 - +474284 BW31 - +474285 OA1 - +474286 OA2 - +474287 OSTEAR3_H - +474288 OA4 - +474289 OA5 - +474290 OA6 - +474291 OA7 - +474292 OA8 - +474293 OA9 - +474294 BW19 - +474295 BW20 - +474296 BFD1 - +474297 BFD2 - +474298 BFD3 - +474299 BFD4 - +474300 BFD5 - +474301 BP5 - +474302 BP6 - +474303 BW11 - +474304 BW33 - +474305 BW32 - +474306 BW34 - +474307 BW18 - +474308 UAE1 - +474309 UAE2 - +474310 OA26 - +474311 BW15 - +474312 BW12 - +474313 BW13 - +474314 BW14 - +474333 GEVQ2 MIM:608878 +474334 GEVQ1 MIM:608875 +474337 SUMO1P2 HGNC:HGNC:33149 +474338 SUMO1P3 HGNC:HGNC:33150 +474341 SUMO1P5 HGNC:HGNC:33152 +474343 SPIN2B MIM:300517|HGNC:HGNC:33147|Ensembl:ENSG00000186787|Vega:OTTHUMG00000021680 +474344 GIMAP6 MIM:616960|HGNC:HGNC:21918|Ensembl:ENSG00000133561|Vega:OTTHUMG00000159137 +474345 GIMAP3P HGNC:HGNC:30975 +474354 LRRC18 HGNC:HGNC:23199|Ensembl:ENSG00000165383|Vega:OTTHUMG00000018182 +474381 H2AFB2 HGNC:HGNC:18298|Ensembl:ENSG00000277858|Vega:OTTHUMG00000034292 +474382 H2AFB1 HGNC:HGNC:22516|Ensembl:ENSG00000274183|Vega:OTTHUMG00000034291 +474383 F8A2 HGNC:HGNC:31849|Ensembl:ENSG00000274791|Vega:OTTHUMG00000034293 +474384 F8A3 HGNC:HGNC:31850|Ensembl:ENSG00000277150|Vega:OTTHUMG00000034289 +474387 OFC4 MIM:608371 +474388 CMM4 MIM:608035 +492295 RAC1P3 HGNC:HGNC:31833 +492303 GEMIN8P4 HGNC:HGNC:37979 +492307 C8orf22 HGNC:HGNC:31745|Ensembl:ENSG00000168333|Vega:OTTHUMG00000164217 +492311 IGIP HGNC:HGNC:33847|Ensembl:ENSG00000182700|Vega:OTTHUMG00000163359 +493753 COA5 MIM:613920|HGNC:HGNC:33848|Ensembl:ENSG00000183513|Vega:OTTHUMG00000153101 +493754 GS1-124K5.11 Ensembl:ENSG00000229180 +493812 HCG11 HGNC:HGNC:17707 +493813 HCG13P HGNC:HGNC:17724 +493816 TUBBP4 HGNC:HGNC:19913 +493818 MYMY3 MIM:608796|HGNC:HGNC:20769 +493821 ZNF603P HGNC:HGNC:23322 +493824 ZNF601P HGNC:HGNC:29407 +493825 POLR2LP1 HGNC:HGNC:31340 +493829 TRIM72 MIM:613288|HGNC:HGNC:32671|Ensembl:ENSG00000177238|Vega:OTTHUMG00000176754 +493856 CISD2 MIM:611507|HGNC:HGNC:24212|Ensembl:ENSG00000145354|Vega:OTTHUMG00000161014 +493860 CCDC73 MIM:612328|HGNC:HGNC:23261|Ensembl:ENSG00000186714|Vega:OTTHUMG00000166279 +493861 EID3 MIM:612986|HGNC:HGNC:32961|Ensembl:ENSG00000255150|Vega:OTTHUMG00000165912 +493862 CTRCT28 MIM:609026 +493869 GPX8 MIM:617172|HGNC:HGNC:33100|Ensembl:ENSG00000164294|Vega:OTTHUMG00000162601 +493900 TMEM9B-AS1 HGNC:HGNC:19230|Ensembl:ENSG00000254860 +493901 RNASE12 HGNC:HGNC:24211|Ensembl:ENSG00000258436|Vega:OTTHUMG00000170991 +493911 PHOSPHO2 HGNC:HGNC:28316|Ensembl:ENSG00000144362|Vega:OTTHUMG00000153981 +493913 PAPPA-AS1 MIM:610689|HGNC:HGNC:35152|Ensembl:ENSG00000256040 +493987 MT1P1 HGNC:HGNC:23681 +494028 CVMRF MIM:300471 +494029 MENOQ1 MIM:300488 +494115 RBMXL1 HGNC:HGNC:25073|Ensembl:ENSG00000213516|Vega:OTTHUMG00000010661 +494118 SPANXN1 MIM:300664|HGNC:HGNC:33174|Ensembl:ENSG00000203923|Vega:OTTHUMG00000022593 +494119 SPANXN2 MIM:300665|HGNC:HGNC:33175|Ensembl:ENSG00000268988|Vega:OTTHUMG00000022583 +494127 LOC494127 - +494141 LOC494141 Ensembl:ENSG00000189332 +494142 DFNM2 HGNC:HGNC:31866 +494143 CHAC2 MIM:617446|HGNC:HGNC:32363|Ensembl:ENSG00000143942|Vega:OTTHUMG00000151824 +494148 DFNB55 MIM:609952|HGNC:HGNC:28876 +494149 DFNB56 HGNC:HGNC:31877 +494150 PHBP19 HGNC:HGNC:51552 +494188 FBXO47 MIM:609498|HGNC:HGNC:31969|Ensembl:ENSG00000204952|Vega:OTTHUMG00000178945 +494197 SPANXN5 MIM:300668|HGNC:HGNC:33178|Ensembl:ENSG00000204363|Vega:OTTHUMG00000021590 +494323 MIR361 HGNC:HGNC:31867|Ensembl:ENSG00000199051|miRBase:MI0000760 +494324 MIR375 MIM:611173|HGNC:HGNC:31868|Ensembl:ENSG00000198973|miRBase:MI0000783 +494325 MIR376A1 MIM:610959|HGNC:HGNC:31869|Ensembl:ENSG00000283588|miRBase:MI0000784 +494326 MIR377 HGNC:HGNC:31870|Ensembl:ENSG00000199015|miRBase:MI0000785 +494327 MIR378A MIM:611957|HGNC:HGNC:31871|Ensembl:ENSG00000199047|miRBase:MI0000786 +494328 MIR379 MIM:616358|HGNC:HGNC:31872|Ensembl:ENSG00000199088|miRBase:MI0000787 +494329 MIR380 MIM:613654|HGNC:HGNC:31873|Ensembl:ENSG00000198982|miRBase:MI0000788 +494330 MIR381 HGNC:HGNC:31874|Ensembl:ENSG00000199020|miRBase:MI0000789 +494331 MIR382 HGNC:HGNC:31875|Ensembl:ENSG00000283170|miRBase:MI0000790 +494332 MIR383 HGNC:HGNC:31876|Ensembl:ENSG00000199127|miRBase:MI0000791 +494333 MIR384 HGNC:HGNC:31878|Ensembl:ENSG00000283242|miRBase:MI0001145 +494334 MIR422A HGNC:HGNC:31879|Ensembl:ENSG00000199156|miRBase:MI0001444 +494335 MIR423 HGNC:HGNC:31880|Ensembl:ENSG00000283935|miRBase:MI0001445 +494336 MIR424 MIM:300682|HGNC:HGNC:31881|Ensembl:ENSG00000284231|miRBase:MI0001446 +494337 MIR425 HGNC:HGNC:31882|Ensembl:ENSG00000199032|miRBase:MI0001448 +494446 NRCLP3 MIM:609039 +494447 COILP2 HGNC:HGNC:25389 +494470 RNF165 HGNC:HGNC:31696|Ensembl:ENSG00000141622|Vega:OTTHUMG00000179230 +494513 PJVK MIM:610219|HGNC:HGNC:29502|Ensembl:ENSG00000204311|Vega:OTTHUMG00000154425 +494514 TYMSOS HGNC:HGNC:29553 +494540 TBCAP1 HGNC:HGNC:42630 +494541 TBCAP2 HGNC:HGNC:42631 +494551 WEE2 MIM:614084|HGNC:HGNC:19684|Ensembl:ENSG00000214102|Vega:OTTHUMG00000157536 +494555 TWF1P2 HGNC:HGNC:21737 +494558 C9orf135-AS1 HGNC:HGNC:48713 +497048 KU-MEL-3 - +497049 FLJ25758 - +497188 GLC1I MIM:609745|HGNC:HGNC:31912 +497189 TIFAB MIM:612663|HGNC:HGNC:34024|Ensembl:ENSG00000255833|Vega:OTTHUMG00000129140 +497190 CLEC18B MIM:616572|HGNC:HGNC:33849|Ensembl:ENSG00000140839|Vega:OTTHUMG00000176998 +497231 CLN9 MIM:609055|HGNC:HGNC:32782 +497256 LOC497256 - +497258 BDNF-AS MIM:611468|HGNC:HGNC:20608|Ensembl:ENSG00000245573 +497259 C18orf61 - +497634 LINC00293 MIM:609543|HGNC:HGNC:39078|Ensembl:ENSG00000253314 +497657 ANIB3 MIM:609122|HGNC:HGNC:31942 +497661 C18orf32 HGNC:HGNC:31690|Ensembl:ENSG00000177576|Vega:OTTHUMG00000179688 +497662 RRIS MIM:609116 +503496 MRX86 HGNC:HGNC:25212 +503497 MS4A13 HGNC:HGNC:16674|Ensembl:ENSG00000204979|Vega:OTTHUMG00000167615 +503519 LINC00929 HGNC:HGNC:48615|Ensembl:ENSG00000259150 +503538 A1BG-AS1 HGNC:HGNC:37133|Ensembl:ENSG00000268895 +503540 LOC503540 - +503542 SPRN MIM:610447|HGNC:HGNC:16871|Ensembl:ENSG00000203772|Vega:OTTHUMG00000019324 +503543 BTF3P9 HGNC:HGNC:38573 +503569 RGMB-AS1 HGNC:HGNC:48666|Ensembl:ENSG00000246763 +503582 ARGFX MIM:611164|HGNC:HGNC:30146|Ensembl:ENSG00000186103|Vega:OTTHUMG00000159395 +503583 ARGFXP1 HGNC:HGNC:17252 +503611 TAAR7P HGNC:HGNC:31925 +503612 TAAR4P HGNC:HGNC:31924 +503613 PSORS10 MIM:612410|HGNC:HGNC:31919 +503614 DEFB107B HGNC:HGNC:31918|Ensembl:ENSG00000198129|Vega:OTTHUMG00000149987 +503618 DEFB104B HGNC:HGNC:26165|Ensembl:ENSG00000177023|Vega:OTTHUMG00000149986 +503627 TPRX2P HGNC:HGNC:32175 +503628 TPRX1P1 HGNC:HGNC:32176 +503630 DUXAP1 HGNC:HGNC:32180 +503631 DUXAP2 HGNC:HGNC:32181 +503632 DUXAP3 HGNC:HGNC:32182 +503633 DUXAP4 HGNC:HGNC:32183 +503634 DUXAP5 HGNC:HGNC:32184 +503635 DUXAP6 HGNC:HGNC:32185 +503636 DUXAP7 HGNC:HGNC:32186 +503637 DUXAP8 HGNC:HGNC:32187|Ensembl:ENSG00000206195 +503638 DUXAP9 HGNC:HGNC:32188 +503639 DUXAP10 HGNC:HGNC:32189 +503640 ARGFXP2 HGNC:HGNC:23977 +503641 DPRXP1 HGNC:HGNC:32167 +503643 DPRXP2 HGNC:HGNC:32168 +503644 DPRXP3 HGNC:HGNC:32169 +503645 DPRXP4 HGNC:HGNC:32170|Ensembl:ENSG00000264743 +503646 DPRXP5 HGNC:HGNC:32171 +503647 DPRXP6 HGNC:HGNC:32172 +503648 DPRXP7 HGNC:HGNC:32173 +503693 LOH12CR2 HGNC:HGNC:26524|Ensembl:ENSG00000205791 +503694 DEFB108A HGNC:HGNC:18089 +503834 DPRX MIM:611165|HGNC:HGNC:32166|Ensembl:ENSG00000204595|Vega:OTTHUMG00000170632 +503835 DUXA MIM:611168|HGNC:HGNC:32179|Ensembl:ENSG00000258873|Vega:OTTHUMG00000170714 +503837 DEFB108C HGNC:HGNC:30847 +503838 DEFB109D HGNC:HGNC:30838 +503839 DEFB109E HGNC:HGNC:30592 +503840 DEFB108E HGNC:HGNC:30174 +503841 DEFB106B HGNC:HGNC:28879|Ensembl:ENSG00000187082|Vega:OTTHUMG00000129312 +504175 OR3D1P HGNC:HGNC:25339 +504180 DEFB105B HGNC:HGNC:29930|Ensembl:ENSG00000186599|Vega:OTTHUMG00000129315 +504181 OR5BN2P HGNC:HGNC:29194 +504185 DEFB108D HGNC:HGNC:26227 +504189 OR8U8 HGNC:HGNC:27538 +504190 OR8U9 HGNC:HGNC:29166 +504191 OR9G9 HGNC:HGNC:31940 +541461 PSHK2 MIM:609153 +541465 CT45A6 MIM:300797|HGNC:HGNC:33271|Ensembl:ENSG00000278289|Vega:OTTHUMG00000188604 +541466 CT45A1 MIM:300648|HGNC:HGNC:33267|Ensembl:ENSG00000268940|Vega:OTTHUMG00000188602 +541468 LURAP1 MIM:616129|HGNC:HGNC:32327|Ensembl:ENSG00000171357|Vega:OTTHUMG00000007605 +541471 MIR4435-2HG MIM:617144|HGNC:HGNC:35163|Ensembl:ENSG00000172965 +541472 LOC541472 Ensembl:ENSG00000179428 +541473 LOC541473 Ensembl:ENSG00000146722 +541565 C8orf58 HGNC:HGNC:32233|Ensembl:ENSG00000241852|Vega:OTTHUMG00000154160 +541578 CXorf40B HGNC:HGNC:17402|Ensembl:ENSG00000197021|Vega:OTTHUMG00000034327 +541611 HSP90AB6P HGNC:HGNC:32540 +542767 PCOTH MIM:617122|HGNC:HGNC:39839|Ensembl:ENSG00000205861 +544315 COPD7 - +544316 COPD23 - +544317 AASTH1 - +544318 OA19 - +544319 BP7 - +544320 OA18 - +544321 OA13 - +544322 OA28 - +544323 OA20 - +544324 OA23 - +544325 OA21 - +544326 BP8 - +544327 OA10 - +544328 OA11 - +544329 OA17 - +544330 BW1 - +544331 OA14 - +544332 OA22 - +544333 OA12 - +544334 OA27 - +544335 OA15 - +544336 BW17 - +544337 BW16 - +544338 BP29 - +544416 COPD19 - +544417 COPD13 - +544418 COPD2 - +544419 COPD14 - +544420 COPD3 - +544421 COPD11 - +544422 COPD25 - +544423 AASTH6 - +544424 COPD16 - +544425 AASTH7 - +544426 COPD18 - +544427 COPD21 - +544428 COPD4 - +544429 COPD8 - +544430 COPD22 - +544431 COPD15 - +544432 COPD12 - +544433 COPD17 - +544434 AASTH5 - +544435 COPD28 - +544436 COPD20 - +544437 COPD26 - +544438 COPD9 - +544439 COPD27 - +544440 AASTH4 - +544441 AASTH3 - +544442 COPD10 - +544443 COPD29 - +544444 COPD1 - +544445 COPD6 - +544446 AASTH2 - +544447 COPD5 - +544448 COPD24 - +544560 AASTH30 - +544561 AASTH31 - +544562 AASTH52 - +544563 AASTH48 - +544564 AASTH34 - +544565 AASTH20 - +544566 AASTH40 - +544567 AASTH14 - +544568 AASTH9 - +544569 AASTH21 - +544570 AASTH25 - +544571 AASTH47 - +544572 AASTH39 - +544573 AASTH17 - +544574 AASTH35 - +544575 AASTH38 - +544576 AASTH26 - +544577 AASTH49 - +544578 AASTH50 - +544579 AASTH12 - +544580 AASTH23 - +544581 AASTH55 - +544582 AASTH42 - +544583 AASTH13 - +544584 AASTH11 - +544585 AASTH36 - +544586 AASTH54 - +544587 AASTH51 - +544588 AASTH33 - +544589 AASTH19 - +544590 AASTH43 - +544591 AASTH8 - +544592 AASTH27 - +544593 AASTH53 - +544594 AASTH44 - +544595 AASTH18 - +544596 AASTH16 - +544597 AASTH15 - +544598 AASTH37 - +544599 AASTH45 - +544600 AASTH24 - +544601 AASTH46 - +544602 AASTH22 - +544603 AASTH10 - +544614 BW59 - +544615 BW56 - +544616 COHEN2 - +544617 BW35 - +544618 COHEN1 - +544619 BW37 - +544620 BW54 - +544621 BW55 - +544622 BW36 - +544623 HRTRT1 - +544624 BW69 - +544625 BW53 - +544626 BW52 - +544627 BW72 - +544628 BW70 - +544629 BW64 - +544630 BW57 - +544631 SLEP2 - +544632 BW61 - +544633 BW71 - +544634 BW60 - +544635 BW66 - +544636 BW58 - +544637 BW62 - +544638 BW68 - +544639 BW67 - +544640 BW63 - +544650 SLEP1 - +548313 SSX4B HGNC:HGNC:16880|Ensembl:ENSG00000269791|Vega:OTTHUMG00000021497 +548593 SLX1A MIM:615822|HGNC:HGNC:20922|Ensembl:ENSG00000132207|Vega:OTTHUMG00000176859 +548594 KIR3DP1 MIM:610604|HGNC:HGNC:16343 +548596 CKMT1A MIM:613415|HGNC:HGNC:31736|Ensembl:ENSG00000223572|Vega:OTTHUMG00000059898 +548599 PHBP7 HGNC:HGNC:39286 +548637 DUTP1 HGNC:HGNC:31956 +548644 POLR2J3 HGNC:HGNC:33853|Ensembl:ENSG00000168255|Vega:OTTHUMG00000150384 +548645 DNAJC25 HGNC:HGNC:34187|Ensembl:ENSG00000059769|Vega:OTTHUMG00000020491 +550112 UBA6-AS1 HGNC:HGNC:49083|Ensembl:ENSG00000248049 +550113 LOC550113 - +550624 KTCN4 MIM:609271 +550625 ANIC MIM:107200 +550626 FHASD MIM:609218 +550631 CCDC157 HGNC:HGNC:33854|Ensembl:ENSG00000187860|Vega:OTTHUMG00000151007 +550641 TELM MIM:609113 +550643 NBDY MIM:300992|HGNC:HGNC:50713 +550644 LOC550644 - +552853 NCRNA00250 Ensembl:ENSG00000253433 +552859 LINC00251 HGNC:HGNC:31950|Ensembl:ENSG00000280725 +552860 SAMD12-AS1 HGNC:HGNC:30937|Ensembl:ENSG00000281641 +552879 VENTXP6 HGNC:HGNC:32216 +552889 ATXN7L3B MIM:615579|HGNC:HGNC:37931|Ensembl:ENSG00000253719|Vega:OTTHUMG00000163936 +552891 DNAJC25-GNG10 HGNC:HGNC:37501|Ensembl:ENSG00000244115|Vega:OTTHUMG00000150303 +552900 BOLA2 MIM:613182|HGNC:HGNC:29488|Ensembl:ENSG00000183336|Vega:OTTHUMG00000176757 +553103 MIR3936HG HGNC:HGNC:40538|Ensembl:ENSG00000233006 +553112 FERP1 HGNC:HGNC:26443 +553115 PEF1 MIM:610033|HGNC:HGNC:30009|Ensembl:ENSG00000162517|Vega:OTTHUMG00000003877 +553117 RPL39P5 HGNC:HGNC:26015 +553118 STK33P1 HGNC:HGNC:26871 +553121 TLK2P2 HGNC:HGNC:22227 +553128 KIR2DL5B MIM:615727|HGNC:HGNC:16346 +553139 LOC553139 - +553140 SLEP3 - +553141 BW88 - +553142 AASTH29 - +553143 BW65 - +553144 AASTH56 - +553145 AASTH32 - +553146 AASTH41 - +553147 AASTH28 - +553148 SERBP1P3 HGNC:HGNC:44630 +553158 PRR5-ARHGAP8 HGNC:HGNC:34512|Ensembl:ENSG00000248405|Vega:OTTHUMG00000160954 +553190 MYP7 MIM:609256|HGNC:HGNC:35435 +553192 MYP8 MIM:609257|HGNC:HGNC:35436 +553194 MYP9 MIM:609258|HGNC:HGNC:35437 +553195 MYP10 MIM:609259|HGNC:HGNC:35438 +553820 EEF1A1P31 HGNC:HGNC:37908 +553939 LOC553939 - +553989 LFS3 MIM:609266 +553991 LGMD1G MIM:609115|HGNC:HGNC:32230 +553992 MGR7 MIM:609179 +554049 C1DP1 HGNC:HGNC:31465 +554175 DNM1P33 HGNC:HGNC:35180 +554188 FCMTE2 MIM:607876|HGNC:HGNC:37159 +554201 CCDC148-AS1 HGNC:HGNC:44134|Ensembl:ENSG00000227480 +554202 MIR31HG MIM:616356|HGNC:HGNC:37187 +554203 JPX MIM:300832|HGNC:HGNC:37191|Ensembl:ENSG00000225470 +554206 LOC554206 Ensembl:ENSG00000262587 +554210 MIR429 MIM:612094|HGNC:HGNC:13784|Ensembl:ENSG00000198976|miRBase:MI0001641 +554212 MIR448 MIM:300686|HGNC:HGNC:26069|Ensembl:ENSG00000199001|miRBase:MI0001637 +554213 MIR449A MIM:613131|HGNC:HGNC:27645|Ensembl:ENSG00000198983|miRBase:MI0001648 +554214 MIR450A1 HGNC:HGNC:28008|Ensembl:ENSG00000199132|miRBase:MI0001652 +554223 LOC554223 Ensembl:ENSG00000181126 +554224 PPIP5K1P1 HGNC:HGNC:32373 +554225 STRCP1 HGNC:HGNC:33915 +554226 ANKRD30BL HGNC:HGNC:35167|Ensembl:ENSG00000163046|Vega:OTTHUMG00000153491 +554234 RPL36AP40 HGNC:HGNC:36300 +554235 ASPDH HGNC:HGNC:33856|Ensembl:ENSG00000204653|Vega:OTTHUMG00000183057 +554236 DPY19L2P1 HGNC:HGNC:22305 +554249 LOC554249 - +554250 GDF5OS HGNC:HGNC:33435 +554251 FBXO48 HGNC:HGNC:33857|Ensembl:ENSG00000204923|Vega:OTTHUMG00000152585 +554279 LINC00862 HGNC:HGNC:21901|Ensembl:ENSG00000203721 +554282 FAM72C MIM:616853|HGNC:HGNC:30602|Ensembl:ENSG00000263513|Vega:OTTHUMG00000041029 +554300 KIR2DP1 HGNC:HGNC:16344 +554313 HIST2H4B HGNC:HGNC:29607|Ensembl:ENSG00000270276|Vega:OTTHUMG00000188201 +554314 AUTS6 MIM:609378 +554315 BMND5 MIM:609354 +554316 BMND4 MIM:300536 +554354 LARP4P HGNC:HGNC:21438 +572558 PGM5-AS1 HGNC:HGNC:44181|Ensembl:ENSG00000224958 +573971 DHFRP1 HGNC:HGNC:2862 +574013 SMAN1 HGNC:HGNC:20975 +574016 CLLU1OS MIM:616989|HGNC:HGNC:24070|Ensembl:ENSG00000205057|Vega:OTTHUMG00000161990 +574028 CLLU1 MIM:616988|HGNC:HGNC:29841|Ensembl:ENSG00000257127|Vega:OTTHUMG00000170103 +574029 DUSP5P1 HGNC:HGNC:32020 +574030 MIR362 HGNC:HGNC:32022|Ensembl:ENSG00000208015|miRBase:MI0000762 +574031 MIR363 HGNC:HGNC:32023|Ensembl:ENSG00000284499|miRBase:MI0000764 +574032 MIR20B MIM:300950|HGNC:HGNC:32024|Ensembl:ENSG00000284043|miRBase:MI0001519 +574033 MIR18B HGNC:HGNC:32025|Ensembl:ENSG00000283931|miRBase:MI0001518 +574034 MIR433 MIM:611711|HGNC:HGNC:32026|Ensembl:ENSG00000207569|miRBase:MI0001723 +574036 SERTAD4-AS1 HGNC:HGNC:32019|Ensembl:ENSG00000203706 +574037 C1orf134 HGNC:HGNC:32021 +574038 MIR431 MIM:611708|HGNC:HGNC:32027|Ensembl:ENSG00000208001|miRBase:MI0001721 +574040 SNORA6 HGNC:HGNC:32591|Ensembl:ENSG00000206760 +574042 SNORA10 HGNC:HGNC:32598|Ensembl:ENSG00000206811 +574043 CDAGS MIM:603116 +574044 EPRPDC MIM:608105 +574045 HNP1 MIM:608026 +574047 MRXSMP MIM:300519 +574048 OVCAS1 MIM:607893 +574049 TUKLS MIM:609428 +574077 GLC1K MIM:608696|HGNC:HGNC:21341 +574078 GLC1J MIM:608695|HGNC:HGNC:26986 +574080 LOC574080 - +574406 ADAMTSL4-AS1 HGNC:HGNC:32041|Ensembl:ENSG00000203804 +574407 OBSCN-AS1 HGNC:HGNC:32047|Ensembl:ENSG00000162913|Vega:OTTHUMG00000039770 +574408 MIR329-1 HGNC:HGNC:32050|Ensembl:ENSG00000207761|miRBase:MI0001725 +574409 MIR329-2 HGNC:HGNC:32051|Ensembl:ENSG00000207762|miRBase:MI0001726 +574410 MIR323B HGNC:HGNC:38349|Ensembl:ENSG00000208004|miRBase:MI0014206 +574411 MIR451A MIM:612071|HGNC:HGNC:32053|Ensembl:ENSG00000284565|miRBase:MI0001729 +574412 MIR452 HGNC:HGNC:32054|Ensembl:ENSG00000283751|miRBase:MI0001733 +574413 MIR409 MIM:614057|HGNC:HGNC:32055|Ensembl:ENSG00000199107|miRBase:MI0001735 +574414 PRR9 HGNC:HGNC:32057|Ensembl:ENSG00000203783|Vega:OTTHUMG00000013936 +574431 C1orf147 HGNC:HGNC:32061 +574432 IBA57-AS1 HGNC:HGNC:32062|Ensembl:ENSG00000203684 +574433 MIR412 HGNC:HGNC:32064|Ensembl:ENSG00000199012|miRBase:MI0002464 +574434 MIR410 MIM:615036|HGNC:HGNC:32065|Ensembl:ENSG00000199092|miRBase:MI0002465 +574435 MIR376B MIM:610961|HGNC:HGNC:32066|Ensembl:ENSG00000283556|miRBase:MI0002466 +574436 MIR485 MIM:615385|HGNC:HGNC:32067|Ensembl:ENSG00000208027|miRBase:MI0002469 +574441 MIR488 HGNC:HGNC:32073|Ensembl:ENSG00000202609|miRBase:MI0003123 +574442 MIR489 MIM:614523|HGNC:HGNC:32074|Ensembl:ENSG00000207656|miRBase:MI0003124 +574443 MIR490 MIM:616972|HGNC:HGNC:32075|Ensembl:ENSG00000207597|miRBase:MI0003125 +574444 MIR491 HGNC:HGNC:32076|Ensembl:ENSG00000207609|miRBase:MI0003126 +574445 MIR511 HGNC:HGNC:32077|Ensembl:ENSG00000207938|miRBase:MI0003127 +574447 MIR146B MIM:610567|HGNC:HGNC:32079|Ensembl:ENSG00000202569|miRBase:MI0003129 +574448 MIR202 HGNC:HGNC:32080|Ensembl:ENSG00000284219|miRBase:MI0003130 +574449 MIR492 MIM:614384|HGNC:HGNC:32081|Ensembl:ENSG00000283998|miRBase:MI0003131 +574450 MIR493 HGNC:HGNC:32082|Ensembl:ENSG00000207989|miRBase:MI0003132 +574451 MIR432 HGNC:HGNC:32083|Ensembl:ENSG00000272458|miRBase:MI0003133 +574452 MIR494 MIM:616036|HGNC:HGNC:32084|Ensembl:ENSG00000194717|miRBase:MI0003134 +574453 MIR495 MIM:615149|HGNC:HGNC:32085|Ensembl:ENSG00000207743|miRBase:MI0003135 +574454 MIR496 HGNC:HGNC:32086|Ensembl:ENSG00000207961|miRBase:MI0003136 +574455 MIR193B MIM:614734|HGNC:HGNC:32087|Ensembl:ENSG00000207639|miRBase:MI0003137 +574456 MIR497 MIM:615672|HGNC:HGNC:32088|Ensembl:ENSG00000284027|miRBase:MI0003138 +574457 MIR181D HGNC:HGNC:32089|Ensembl:ENSG00000207585|miRBase:MI0003139 +574458 MIR512-1 HGNC:HGNC:32090|Ensembl:ENSG00000207645|miRBase:MI0003140 +574459 MIR512-2 HGNC:HGNC:32091|Ensembl:ENSG00000207644|miRBase:MI0003141 +574460 MIR498 HGNC:HGNC:32092|Ensembl:ENSG00000207869|miRBase:MI0003142 +574461 MIR520E HGNC:HGNC:32093|Ensembl:ENSG00000207599|miRBase:MI0003143 +574462 MIR515-1 HGNC:HGNC:32094|Ensembl:ENSG00000207616|miRBase:MI0003144 +574463 MIR519E HGNC:HGNC:32095|Ensembl:ENSG00000207810|miRBase:MI0003145 +574464 MIR520F HGNC:HGNC:32096|Ensembl:ENSG00000283540|miRBase:MI0003146 +574465 MIR515-2 HGNC:HGNC:32097|Ensembl:ENSG00000207615|miRBase:MI0003147 +574466 MIR519C HGNC:HGNC:32098|Ensembl:ENSG00000207788|miRBase:MI0003148 +574467 MIR520A HGNC:HGNC:32099|Ensembl:ENSG00000207594|miRBase:MI0003149 +574468 MIR526B HGNC:HGNC:32100|Ensembl:ENSG00000207580|miRBase:MI0003150 +574469 MIR519B HGNC:HGNC:32101|Ensembl:ENSG00000207825|miRBase:MI0003151 +574470 MIR525 HGNC:HGNC:32102|Ensembl:ENSG00000207711|miRBase:MI0003152 +574471 MIR523 HGNC:HGNC:32103|Ensembl:ENSG00000283455|miRBase:MI0003153 +574472 MIR518F HGNC:HGNC:32104|Ensembl:ENSG00000207706|miRBase:MI0003154 +574473 MIR520B HGNC:HGNC:32105|Ensembl:ENSG00000207722|miRBase:MI0003155 +574474 MIR518B HGNC:HGNC:32106|Ensembl:ENSG00000207862|miRBase:MI0003156 +574475 MIR526A1 HGNC:HGNC:32107|Ensembl:ENSG00000207629|miRBase:MI0003157 +574476 MIR520C MIM:615908|HGNC:HGNC:32108|Ensembl:ENSG00000207738|miRBase:MI0003158 +574477 MIR518C HGNC:HGNC:32109|Ensembl:ENSG00000283490|miRBase:MI0003159 +574478 MIR524 HGNC:HGNC:32110|Ensembl:ENSG00000283289|miRBase:MI0003160 +574479 MIR517A HGNC:HGNC:32111|Ensembl:ENSG00000207734|miRBase:MI0003161 +574480 MIR519D MIM:614247|HGNC:HGNC:32112|Ensembl:ENSG00000207981|miRBase:MI0003162 +574481 MIR521-2 HGNC:HGNC:32113|Ensembl:ENSG00000207549|miRBase:MI0003163 +574482 MIR520D HGNC:HGNC:32114|Ensembl:ENSG00000207735|miRBase:MI0003164 +574483 MIR517B HGNC:HGNC:32115|Ensembl:ENSG00000207837|miRBase:MI0003165 +574484 MIR520G MIM:616272|HGNC:HGNC:32116|Ensembl:ENSG00000207799|miRBase:MI0003166 +574485 MIR516B2 HGNC:HGNC:32117|Ensembl:ENSG00000207925|miRBase:MI0003167 +574486 MIR526A2 HGNC:HGNC:32118|Ensembl:ENSG00000211532|miRBase:MI0003168 +574487 MIR518E HGNC:HGNC:32119|Ensembl:ENSG00000207987|miRBase:MI0003169 +574488 MIR518A1 HGNC:HGNC:32120|Ensembl:ENSG00000207803|miRBase:MI0003170 +574489 MIR518D HGNC:HGNC:32121|Ensembl:ENSG00000283330|miRBase:MI0003171 +574490 MIR516B1 HGNC:HGNC:32122|Ensembl:ENSG00000207946|miRBase:MI0003172 +574491 MIR518A2 HGNC:HGNC:32123|Ensembl:ENSG00000207699|miRBase:MI0003173 +574492 MIR517C HGNC:HGNC:32124|Ensembl:ENSG00000207838|miRBase:MI0003174 +574493 MIR520H MIM:614755|HGNC:HGNC:32125|Ensembl:ENSG00000207861|miRBase:MI0003175 +574494 MIR521-1 HGNC:HGNC:32126|Ensembl:ENSG00000207634|miRBase:MI0003176 +574495 MIR522 HGNC:HGNC:32127|Ensembl:ENSG00000283685|miRBase:MI0003177 +574496 MIR519A1 HGNC:HGNC:32128|Ensembl:ENSG00000207992|miRBase:MI0003178 +574497 MIR527 HGNC:HGNC:32129|Ensembl:ENSG00000207979|miRBase:MI0003179 +574498 MIR516A1 HGNC:HGNC:32130|Ensembl:ENSG00000207767|miRBase:MI0003180 +574499 MIR516A2 HGNC:HGNC:32131|Ensembl:ENSG00000207620|miRBase:MI0003181 +574500 MIR519A2 HGNC:HGNC:32132|Ensembl:ENSG00000284362|miRBase:MI0003182 +574501 MIR499A MIM:613614|HGNC:HGNC:32133|Ensembl:ENSG00000207635|miRBase:MI0003183 +574502 MIR500A HGNC:HGNC:32134|Ensembl:ENSG00000207785|miRBase:MI0003184 +574503 MIR501 HGNC:HGNC:32135|Ensembl:ENSG00000211538|miRBase:MI0003185 +574504 MIR502 MIM:300893|HGNC:HGNC:32136|Ensembl:ENSG00000272080|miRBase:MI0003186 +574505 MIR450A2 HGNC:HGNC:32137|Ensembl:ENSG00000207755|miRBase:MI0003187 +574506 MIR503 MIM:300865|HGNC:HGNC:32138|Ensembl:ENSG00000208005|miRBase:MI0003188 +574507 MIR504 HGNC:HGNC:32139|Ensembl:ENSG00000207800|miRBase:MI0003189 +574508 MIR505 HGNC:HGNC:32140|Ensembl:ENSG00000207633|miRBase:MI0003190 +574509 MIR513A1 HGNC:HGNC:32141|Ensembl:ENSG00000207873|miRBase:MI0003191 +574510 MIR513A2 HGNC:HGNC:32142|Ensembl:ENSG00000207984|miRBase:MI0003192 +574511 MIR506 MIM:300877|HGNC:HGNC:32143|Ensembl:ENSG00000207731|miRBase:MI0003193 +574512 MIR507 HGNC:HGNC:32144|Ensembl:ENSG00000207969|miRBase:MI0003194 +574513 MIR508 MIM:300874|HGNC:HGNC:32145|Ensembl:ENSG00000207589|miRBase:MI0003195 +574514 MIR509-1 MIM:300875|HGNC:HGNC:32146|Ensembl:ENSG00000208000|miRBase:MI0003196 +574515 MIR510 MIM:300866|HGNC:HGNC:32147|Ensembl:ENSG00000207641|miRBase:MI0003197 +574516 MIR514A1 HGNC:HGNC:32148|Ensembl:ENSG00000207868|miRBase:MI0003198 +574517 MIR514A2 HGNC:HGNC:32149|Ensembl:ENSG00000207866|miRBase:MI0003199 +574518 MIR514A3 HGNC:HGNC:32150|Ensembl:ENSG00000207867|miRBase:MI0003200 +574532 NUDT15P1 HGNC:HGNC:17266 +574533 NUDT15P2 HGNC:HGNC:20784 +574537 UGT2A2 HGNC:HGNC:28183|Ensembl:ENSG00000271271|Vega:OTTHUMG00000129398 +574538 LOC574538 Ensembl:ENSG00000249695 +594832 MYP11 MIM:609994|HGNC:HGNC:24906 +594837 SNORD101 HGNC:HGNC:32764|Ensembl:ENSG00000206754 +594838 SNORD100 HGNC:HGNC:32763|Ensembl:ENSG00000221500 +594839 SNORA33 HGNC:HGNC:32623|Ensembl:ENSG00000200534 +594840 ZFAT-AS1 HGNC:HGNC:33992|Ensembl:ENSG00000248492 +594841 WDR45P1 HGNC:HGNC:52406 +594842 HAS2-AS1 MIM:614353|HGNC:HGNC:34340 +594855 CPLX3 MIM:609585|HGNC:HGNC:27652|Ensembl:ENSG00000213578|Vega:OTTHUMG00000142816 +594857 NPS MIM:609513|HGNC:HGNC:33940|Ensembl:ENSG00000214285|Vega:OTTHUMG00000188145 +595097 SNORD16 HGNC:HGNC:32712|Ensembl:ENSG00000199673 +595098 SNORD18A HGNC:HGNC:32714|Ensembl:ENSG00000200623 +595099 SNORD18B HGNC:HGNC:32715|Ensembl:ENSG00000202529|Ensembl:ENSG00000280554 +595100 SNORD18C HGNC:HGNC:32716|Ensembl:ENSG00000199574 +595101 SMG1P5 HGNC:HGNC:49862|Ensembl:ENSG00000183604 +595135 PGM5P2 HGNC:HGNC:18965|Ensembl:ENSG00000277778 +606293 KLKP1 HGNC:HGNC:21260|Ensembl:ENSG00000197588 +606495 CYB5RL HGNC:HGNC:32220|Ensembl:ENSG00000215883|Vega:OTTHUMG00000008082 +606500 SNORD68 HGNC:HGNC:32729 +606551 UBE2MP1 HGNC:HGNC:32195 +606553 C8orf49 HGNC:HGNC:32200|Ensembl:ENSG00000255394 +606724 LOC606724 - +613037 NPIPB13 HGNC:HGNC:41989|Ensembl:ENSG00000198064|Vega:OTTHUMG00000163556 +613038 LOC613038 Ensembl:ENSG00000258130|Vega:OTTHUMG00000170482 +613126 CYP51A1-AS1 HGNC:HGNC:50694|Ensembl:ENSG00000188693 +613204 IFITM8P HGNC:HGNC:32202 +613206 LOC613206 - +613209 DEFB135 HGNC:HGNC:32400|Ensembl:ENSG00000205883|Vega:OTTHUMG00000158719 +613210 DEFB136 HGNC:HGNC:34433|Ensembl:ENSG00000205884|Vega:OTTHUMG00000158720 +613211 DEFB134 HGNC:HGNC:32399|Ensembl:ENSG00000205882|Vega:OTTHUMG00000158718 +613212 CTXN3 HGNC:HGNC:31110|Ensembl:ENSG00000205279|Vega:OTTHUMG00000163285 +613227 HIGD1C HGNC:HGNC:28044|Ensembl:ENSG00000214511|Vega:OTTHUMG00000169488 +613253 DEFA1A3 HGNC:HGNC:32231 +613266 LOC613266 - +619189 SERINC4 MIM:614550|HGNC:HGNC:32237|Ensembl:ENSG00000184716|Vega:OTTHUMG00000060144 +619190 FDPSP2 HGNC:HGNC:3633 +619207 SCART1 HGNC:HGNC:32411|Ensembl:ENSG00000214279 +619208 FAM229B HGNC:HGNC:33858|Ensembl:ENSG00000203778|Vega:OTTHUMG00000015383 +619211 DFNB58 HGNC:HGNC:18252 +619212 PA2G4P3 HGNC:HGNC:31731 +619279 ZNF704 HGNC:HGNC:32291|Ensembl:ENSG00000164684|Vega:OTTHUMG00000164733 +619344 LINC01298 HGNC:HGNC:32292|Ensembl:ENSG00000253351 +619349 SETP3 HGNC:HGNC:31115 +619351 LINC00589 HGNC:HGNC:32299|Ensembl:ENSG00000251191 +619370 MCDR4 HGNC:HGNC:32303 +619373 MBOAT4 MIM:611940|HGNC:HGNC:32311|Ensembl:ENSG00000177669|Vega:OTTHUMG00000163824 +619379 SPG29 MIM:609727|HGNC:HGNC:30161 +619383 SCARNA9 HGNC:HGNC:32566|Ensembl:ENSG00000254911 +619394 SPOAN MIM:609541 +619397 FEB6 MIM:609253|HGNC:HGNC:33478 +619398 FEB5 MIM:609255|HGNC:HGNC:33477 +619399 ETL2 MIM:608096 +619402 HPC5 MIM:609299 +619404 CTRCT35 MIM:609376 +619405 AIS4 MIM:609400 +619406 HPE8 MIM:609408 +619407 MSSD MIM:609432 +619408 PSNP2 MIM:609454 +619409 MDCMP MIM:609456 +619410 NEDE MIM:609469 +619411 LVNC2 MIM:609470 +619418 FAM90A21P HGNC:HGNC:32269 +619423 FAM85A HGNC:HGNC:17606 +619434 LINC00051 HGNC:HGNC:32028|Ensembl:ENSG00000254008 +619443 RPS26P7 HGNC:HGNC:20077 +619445 RPL10P3 HGNC:HGNC:23300 +619448 RPS12P2 HGNC:HGNC:24221 +619449 RPIAP1 HGNC:HGNC:27250 +619452 RPS29P2 HGNC:HGNC:31083 +619455 SPANXA2-OT1 HGNC:HGNC:31683|Ensembl:ENSG00000277215 +619457 UBE2WP1 HGNC:HGNC:32198 +619464 RPL31P9 HGNC:HGNC:31893 +619465 ERVK-8 HGNC:HGNC:32302 +619468 RCM2 MIM:609578 +619469 DELYQ11 MIM:400042 +619471 PPR3 MIM:609573 +619475 PFM3 MIM:609566|HGNC:HGNC:20094 +619477 GCCD3 MIM:609197 +619478 ATFB2 MIM:608988 +619479 STQTL5 MIM:608982 +619480 MDBS2 MIM:608970 +619488 SCZD12 MIM:608543 +619493 PAND2 MIM:607853 +619496 CMT2H MIM:607731 +619498 SNORD74 HGNC:HGNC:32734 +619499 SNORA27 HGNC:HGNC:32617|Ensembl:ENSG00000207051 +619501 HCC MIM:607464 +619503 FIQTL1 MIM:606035 +619505 SNORA21 HGNC:HGNC:32611|Ensembl:ENSG00000199293 +619509 WTRS MIM:300421 +619510 AMCX5 MIM:300158 +619511 MHB MIM:255160 +619518 SSBP3-AS1 HGNC:HGNC:32328|Ensembl:ENSG00000198711 +619519 TWF1P1 HGNC:HGNC:21736 +619536 BPPV MIM:193007 +619537 VV MIM:192200 +619538 OMS MIM:166760 +619539 LOC619539 MIM:151001 +619540 LOC619540 MIM:148600 +619552 MIR483 HGNC:HGNC:32340|Ensembl:ENSG00000207805|miRBase:MI0002467 +619553 MIR484 HGNC:HGNC:32341|Ensembl:ENSG00000283736|miRBase:MI0002468 +619554 MIR486-1 HGNC:HGNC:32342|Ensembl:ENSG00000274705|miRBase:MI0002470 +619555 MIR487A HGNC:HGNC:32343|Ensembl:ENSG00000207742|miRBase:MI0002471 +619556 MIR455 HGNC:HGNC:32344|Ensembl:ENSG00000207726|miRBase:MI0003513 +619562 SNORA3A HGNC:HGNC:32586|Ensembl:ENSG00000200983 +619563 SNORA7A HGNC:HGNC:32592|Ensembl:ENSG00000207496 +619564 SNORD72 HGNC:HGNC:32733|Ensembl:ENSG00000212296 +619565 SNORA52 HGNC:HGNC:32645|Ensembl:ENSG00000199785 +619567 SNORD2 HGNC:HGNC:32678|Ensembl:ENSG00000238942 +619568 SNORA4 HGNC:HGNC:32587|Ensembl:ENSG00000263776 +619569 SNORA41 HGNC:HGNC:32634|Ensembl:ENSG00000207406 +619570 SNORD95 HGNC:HGNC:32757|Ensembl:ENSG00000264549 +619571 SNORD96A HGNC:HGNC:32758|Ensembl:ENSG00000272296 +641293 RPL21P19 HGNC:HGNC:35748 +641298 SMG1P1 HGNC:HGNC:44186|Ensembl:ENSG00000237296 +641311 RPL31P11 HGNC:HGNC:35849|Ensembl:ENSG00000213075 +641312 SAR1AP2 HGNC:HGNC:20770 +641339 ZNF674 MIM:300573|HGNC:HGNC:17625|Ensembl:ENSG00000251192|Vega:OTTHUMG00000021420 +641364 SLC7A11-AS1 HGNC:HGNC:44064|Ensembl:ENSG00000250033 +641365 LINC00616 HGNC:HGNC:44065|Ensembl:ENSG00000248307 +641367 LOC641367 Ensembl:ENSG00000269845 +641371 ACOT1 MIM:614313|HGNC:HGNC:33128|Ensembl:ENSG00000184227|Vega:OTTHUMG00000171607 +641372 ACOT6 MIM:614267|HGNC:HGNC:33159|Ensembl:ENSG00000205669|Vega:OTTHUMG00000171609 +641373 NRON MIM:609618|HGNC:HGNC:37079 +641378 LOC641378 - +641379 ARL5AP4 HGNC:HGNC:43936 +641380 ARL5AP2 HGNC:HGNC:43937 +641381 LOC641381 - +641382 ARL5AP1 HGNC:HGNC:43933 +641384 TMEM75 HGNC:HGNC:32295|Ensembl:ENSG00000280055 +641433 RP32 MIM:609913|HGNC:HGNC:21902 +641451 SNORA19 HGNC:HGNC:32609|Ensembl:ENSG00000207468 +641455 POTEM HGNC:HGNC:37096|Ensembl:ENSG00000222036|Vega:OTTHUMG00000170340 +641456 CRIP1P2 HGNC:HGNC:44517 +641457 CRIP1P4 HGNC:HGNC:44519 +641467 TSC22D1-AS1 HGNC:HGNC:43684|Ensembl:ENSG00000278156 +641515 MGAT4EP HGNC:HGNC:49418|Ensembl:ENSG00000184774 +641516 KC6 Ensembl:ENSG00000267313 +641517 DEFB109B HGNC:HGNC:33469|Ensembl:ENSG00000206034 +641518 LEF1-AS1 HGNC:HGNC:40339|Ensembl:ENSG00000232021 +641556 RPL36AP6 HGNC:HGNC:23365 +641589 LOC641589 - +641613 RPL21P5 HGNC:HGNC:23541 +641614 RPL23AP8 HGNC:HGNC:23543 +641616 RPL9P3 HGNC:HGNC:23555 +641638 SNHG6 MIM:612215|HGNC:HGNC:32965 +641648 SNORD87 MIM:612216|HGNC:HGNC:32746|Ensembl:ENSG00000254341 +641649 TMEM91 HGNC:HGNC:32393|Ensembl:ENSG00000142046|Vega:OTTHUMG00000168127 +641654 HEPN1 MIM:611641|HGNC:HGNC:34400|Ensembl:ENSG00000221932|Vega:OTTHUMG00000165939 +641695 LOC641695 - +641700 ECSCR MIM:615736|HGNC:HGNC:35454|Ensembl:ENSG00000249751|Ensembl:ENSG00000279686|Vega:OTTHUMG00000163240|Vega:OTTHUMG00000189234 +641702 FAM138F HGNC:HGNC:33581|Ensembl:ENSG00000282591 +641708 LOC641708 - +641746 LOC641746 - +641776 SPDYE14P HGNC:HGNC:51510 +641790 RPL31P39 HGNC:HGNC:35995 +641808 FAM185BP HGNC:HGNC:21813 +641842 SLC23A4P HGNC:HGNC:20602 +641922 UNC93B2 HGNC:HGNC:13482 +641924 FAM86LP HGNC:HGNC:44099 +641977 SEPT7P2 MIM:611563|HGNC:HGNC:32339|Ensembl:ENSG00000214765 +642006 GUSBP10 HGNC:HGNC:42324 +642007 GUSBP12 HGNC:HGNC:42326 +642131 LOC642131 - +642204 LOC642204 - +642236 FRG1JP HGNC:HGNC:51768 +642249 LOC642249 - +642259 GAPDHP70 HGNC:HGNC:4148 +642262 NCOA4P4 HGNC:HGNC:52405 +642273 FAM110C MIM:611395|HGNC:HGNC:33340|Ensembl:ENSG00000184731|Vega:OTTHUMG00000151321 +642280 ZNF876P HGNC:HGNC:32472|Ensembl:ENSG00000198155 +642288 CSPG4P9 HGNC:HGNC:48360 +642290 SLC25A1P5 HGNC:HGNC:43849 +642305 MAPRE1P2 HGNC:HGNC:37761 +642306 RPL19P15 HGNC:HGNC:35920 +642311 BMS1P15 HGNC:HGNC:49160 +642317 GAPDHP15 HGNC:HGNC:13950 +642319 TAGLN2P2 HGNC:HGNC:31039 +642320 RPL36AP31 HGNC:HGNC:36066 +642337 FTLP17 HGNC:HGNC:37967 +642345 MIR4500HG HGNC:HGNC:42773|Ensembl:ENSG00000228824 +642355 LOC642355 - +642357 EEF1GP5 HGNC:HGNC:44560 +642361 LOC642361 Ensembl:ENSG00000272447 +642366 LOC642366 - +642381 LOC642381 - +642389 RBM17P2 HGNC:HGNC:50367 +642394 ADARB2-AS1 HGNC:HGNC:23299|Ensembl:ENSG00000205696 +642395 PSPC1P1 HGNC:HGNC:42033 +642402 GOLGA6L17P HGNC:HGNC:49414 +642413 CTSLP6 HGNC:HGNC:23611 +642414 LOC642414 - +642422 LOC642422 - +642423 LOC642423 - +642424 IGKV1OR10-1 HGNC:HGNC:44978|IMGT/GENE-DB:IGKV1/OR10-1 +642425 TRIM53BP HGNC:HGNC:37144 +642426 LINC02297 HGNC:HGNC:53214|Ensembl:ENSG00000257504 +642443 ADH5P4 HGNC:HGNC:21377 +642446 TRIM64B HGNC:HGNC:37147|Ensembl:ENSG00000189253|Vega:OTTHUMG00000167638 +642448 KRT18P23 HGNC:HGNC:33392 +642451 RPL7P46 HGNC:HGNC:36706 +642460 ANKRD30BP1 HGNC:HGNC:19722 +642461 IARS2P1 HGNC:HGNC:50474 +642474 LOC642474 - +642475 MROH6 HGNC:HGNC:27814|Ensembl:ENSG00000204839|Vega:OTTHUMG00000165164 +642477 LINC01296 HGNC:HGNC:48904 +642484 LOC642484 - +642487 LOC642487 - +642489 FKBP1C HGNC:HGNC:21376 +642490 LOC642490 - +642493 RPL29P25 HGNC:HGNC:37039 +642496 LOC642496 - +642502 LOC642502 - +642513 KCTD9P6 HGNC:HGNC:49915 +642515 LOC642515 Ensembl:ENSG00000283526|Vega:OTTHUMG00000191656 +642517 AGAP9 HGNC:HGNC:23463|Ensembl:ENSG00000204172|Vega:OTTHUMG00000018115 +642521 C1DP3 HGNC:HGNC:31661 +642531 RPL36P11 HGNC:HGNC:36271 +642538 C1DP2 HGNC:HGNC:31660 +642546 HK2P1 HGNC:HGNC:4924 +642550 LOC642550 - +642554 LOC642554 - +642559 POU5F1P3 HGNC:HGNC:9222|Ensembl:ENSG00000235602 +642569 TRIM53AP HGNC:HGNC:19025|Ensembl:ENSG00000225581 +642574 IQANK1 HGNC:HGNC:49576 +642579 LOC642579 - +642580 HSPA8P14 HGNC:HGNC:44929 +642585 VDAC1P1 HGNC:HGNC:12671 +642587 MIR205HG HGNC:HGNC:43562 +642590 LOC642590 - +642592 EIF5AP4 HGNC:HGNC:31442 +642597 AKAIN1 MIM:616427|HGNC:HGNC:28285|Ensembl:ENSG00000231824|Vega:OTTHUMG00000178457 +642612 TRIM49C HGNC:HGNC:38877|Ensembl:ENSG00000204449|Vega:OTTHUMG00000167653 +642614 C2orf69P2 HGNC:HGNC:51801 +642623 UBTFL1 MIM:613696|HGNC:HGNC:14533|Ensembl:ENSG00000255009|Vega:OTTHUMG00000155291 +642627 MYL6P4 HGNC:HGNC:37813 +642631 TSPY15P HGNC:HGNC:37474 +642633 FAM230B HGNC:HGNC:32943|Ensembl:ENSG00000215498 +642635 LOC642635 - +642636 RAD21L1 HGNC:HGNC:16271|Ensembl:ENSG00000244588|Vega:OTTHUMG00000031664 +642641 RPSAP54 HGNC:HGNC:36373 +642643 LINC01662 HGNC:HGNC:52450|Ensembl:ENSG00000182824 +642648 LOC642648 - +642652 RARRES2P8 HGNC:HGNC:48707 +642658 SCX MIM:609067|HGNC:HGNC:32322|Ensembl:ENSG00000260428|Vega:OTTHUMG00000175582 +642659 HNRNPA1P48 HGNC:HGNC:48778 +642661 LOC642661 - +642663 CICP17 HGNC:HGNC:48827 +642669 LOC642669 - +642677 LOC642677 - +642683 KIF18BP1 HGNC:HGNC:51808 +642687 RPS11P7 HGNC:HGNC:36724 +642692 LOC642692 - +642696 LOC642696 - +642721 CBX3P6 HGNC:HGNC:42878 +642737 SETP22 HGNC:HGNC:42941 +642738 RPL21P69 HGNC:HGNC:36753 +642740 RPL9P11 HGNC:HGNC:35621 +642741 RPL3P7 HGNC:HGNC:36797 +642746 EIF4A1P9 HGNC:HGNC:37928 +642757 TBC1D22A-AS1 HGNC:HGNC:51221|Ensembl:ENSG00000280080 +642762 ABCD1P5 HGNC:HGNC:42662 +642776 DANT2 HGNC:HGNC:50862|Ensembl:ENSG00000235244 +642778 NPIPA3 HGNC:HGNC:41978|Ensembl:ENSG00000224712|Vega:OTTHUMG00000166262 +642791 LOC642791 - +642796 TSPY18P HGNC:HGNC:37725 +642797 DNAH10OS HGNC:HGNC:37121 +642799 NPIPA2 HGNC:HGNC:41979|Ensembl:ENSG00000254852|Vega:OTTHUMG00000166264 +642802 CCDC137P HGNC:HGNC:33459 +642812 API5P1 HGNC:HGNC:595 +642818 ST13P21 HGNC:HGNC:38864 +642819 ZNF487 HGNC:HGNC:23488 +642826 BMS1P6 HGNC:HGNC:23654 +642828 RPL6P10 HGNC:HGNC:36575 +642840 MEP1AP1 HGNC:HGNC:7016 +642843 CPSF4L HGNC:HGNC:33632|Ensembl:ENSG00000187959|Vega:OTTHUMG00000132640 +642846 LOC642846 - +642852 LOC642852 - +642862 LOC642862 - +642864 SPATA42 HGNC:HGNC:41198|Ensembl:ENSG00000203897 +642869 SETP4 HGNC:HGNC:42923 +642879 SMARCE1P4 HGNC:HGNC:39735 +642888 CNN2P2 HGNC:HGNC:39527 +642890 LOC642890 - +642892 RPS29P3 HGNC:HGNC:31363 +642897 LOC642897 - +642907 NIFKP8 HGNC:HGNC:44956 +642909 CTBP2P4 HGNC:HGNC:45196 +642924 LINC00535 HGNC:HGNC:43644|Ensembl:ENSG00000246662 +642929 LOC642929 Ensembl:ENSG00000278849 +642934 CERNA2 MIM:617434|HGNC:HGNC:51354 +642935 ADAMTS7P4 HGNC:HGNC:49410 +642938 FAM196A MIM:617129|HGNC:HGNC:33859|Ensembl:ENSG00000188916|Vega:OTTHUMG00000019248 +642943 LOC642943 - +642946 FLVCR1-AS1 MIM:610864|HGNC:HGNC:39077|Ensembl:ENSG00000198468 +642952 SNX18P2 HGNC:HGNC:39610 +642954 RBBP4P1 HGNC:HGNC:42368 +642956 FABP5P9 HGNC:HGNC:31064 +642958 HNRNPA1P55 HGNC:HGNC:48785 +642959 ALOX15P2 HGNC:HGNC:39027 +642968 FAM163B HGNC:HGNC:33277|Ensembl:ENSG00000196990|Vega:OTTHUMG00000159557 +642969 LOC642969 - +642975 LOC642975 - +642976 GRIK1-AS1 HGNC:HGNC:16458 +642987 TMEM232 HGNC:HGNC:37270|Ensembl:ENSG00000186952|Vega:OTTHUMG00000163297 +642996 NFE2L3P1 HGNC:HGNC:22278 +643001 DUX4L17 HGNC:HGNC:37717 +643003 RPS26P28 HGNC:HGNC:36149 +643007 RPL36AP8 HGNC:HGNC:30973 +643008 SMIM5 HGNC:HGNC:40030|Ensembl:ENSG00000204323|Vega:OTTHUMG00000167882 +643014 LOC643014 - +643015 LOC643015 - +643031 MTND5P10 HGNC:HGNC:42272 +643034 DUX4L19 HGNC:HGNC:37718 +643036 SLED1 Ensembl:ENSG00000249138 +643037 C11orf97 HGNC:HGNC:49544|Ensembl:ENSG00000257057|Vega:OTTHUMG00000167794 +643043 LOC643043 - +643050 ACTR3BP1 HGNC:HGNC:37724 +643058 LOC643058 - +643067 LOC643067 - +643072 LOC643072 - +643101 RPL26P22 HGNC:HGNC:36244 +643115 KRT223P HGNC:HGNC:32968 +643118 LOC643118 - +643126 TRIM51JP HGNC:HGNC:43978 +643136 ZC3H11B HGNC:HGNC:25659 +643155 SMIM15 HGNC:HGNC:33861|Ensembl:ENSG00000188725|Vega:OTTHUMG00000162241 +643157 MEP1AP4 HGNC:HGNC:39138 +643159 ATF4P3 HGNC:HGNC:788 +643160 CYMP MIM:118943|HGNC:HGNC:2588|Ensembl:ENSG00000240194 +643161 FAM25A HGNC:HGNC:23436|Ensembl:ENSG00000188100|Vega:OTTHUMG00000018664 +643167 LOC643167 - +643168 LOC643168 - +643171 GGT4P HGNC:HGNC:33207 +643172 LOC643172 - +643180 CCT6P3 HGNC:HGNC:35137|Ensembl:ENSG00000234585 +643181 FADS2P1 HGNC:HGNC:43618 +643182 UBTFL8 HGNC:HGNC:44476 +643193 CALM2P4 HGNC:HGNC:39661 +643198 RBPJP6 HGNC:HGNC:37486 +643199 TAB3P1 HGNC:HGNC:37723 +643201 LOC643201 Ensembl:ENSG00000248596 +643205 RPL36P8 HGNC:HGNC:36493 +643210 EHMT1-IT1 HGNC:HGNC:48714 +643219 GPAT2P1 HGNC:HGNC:52330 +643220 RPL3P6 HGNC:HGNC:36395 +643224 TUBBP5 HGNC:HGNC:23674 +643226 GRXCR2 MIM:615762|HGNC:HGNC:33862|Ensembl:ENSG00000204928|Vega:OTTHUMG00000163417 +643228 GAPDHP30 HGNC:HGNC:37782 +643232 NRBF2P3 HGNC:HGNC:44606 +643236 TMEM72 HGNC:HGNC:31658|Ensembl:ENSG00000187783|Vega:OTTHUMG00000018067 +643244 RDXP1 HGNC:HGNC:9945 +643246 MAP1LC3B2 HGNC:HGNC:34390|Ensembl:ENSG00000258102|Vega:OTTHUMG00000171525 +643253 CCT6P1 HGNC:HGNC:33094 +643255 RARRES2P1 HGNC:HGNC:48700 +643263 SSU72P6 HGNC:HGNC:43625 +643264 RPL21P106 HGNC:HGNC:36188 +643276 NOC2LP1 HGNC:HGNC:52285 +643284 RPS29P18 HGNC:HGNC:37004 +643300 HSPD1P1 HGNC:HGNC:35133 +643307 LOC643307 - +643308 RPL7P59 HGNC:HGNC:49215 +643309 ACTBP1 HGNC:HGNC:134 +643310 ST13P18 HGNC:HGNC:38861 +643311 CT47B1 MIM:300790|HGNC:HGNC:33293|Ensembl:ENSG00000236446|Vega:OTTHUMG00000187483 +643314 KIAA0754 HGNC:HGNC:29111|Ensembl:ENSG00000127603|Vega:OTTHUMG00000007754 +643327 LOC643327 - +643329 KRT18P57 HGNC:HGNC:48884 +643332 ECRP - +643336 CDC42P2 HGNC:HGNC:33952 +643338 C15orf62 HGNC:HGNC:34489|Ensembl:ENSG00000188277|Vega:OTTHUMG00000172536 +643339 LOC643339 - +643342 LOC643342 - +643343 RPL5P4 HGNC:HGNC:36095 +643348 LOC643348 - +643353 SAPCD2P3 HGNC:HGNC:51279 +643355 LINC01750 HGNC:HGNC:52538 +643358 RPS27AP16 HGNC:HGNC:36855 +643365 LINC00452 HGNC:HGNC:42800 +643367 LOC643367 - +643371 LOC643371 - +643373 LOC643373 - +643376 BTBD18 HGNC:HGNC:37214|Ensembl:ENSG00000233436|Vega:OTTHUMG00000167203 +643381 LOC643381 - +643382 TMEM253 HGNC:HGNC:32545|Ensembl:ENSG00000232070|Vega:OTTHUMG00000171361 +643384 UNC93B4 HGNC:HGNC:13484 +643387 LOC643387 - +643394 SPINK9 MIM:613511|HGNC:HGNC:32951|Ensembl:ENSG00000204909|Vega:OTTHUMG00000163431 +643401 LINC01021 HGNC:HGNC:48995|Ensembl:ENSG00000250337 +643406 LOC643406 - +643412 BTF3P16 HGNC:HGNC:38568 +643414 LIPK MIM:613922|HGNC:HGNC:23444|Ensembl:ENSG00000204021|Vega:OTTHUMG00000018693 +643418 LIPN MIM:613924|HGNC:HGNC:23452|Ensembl:ENSG00000204020|Vega:OTTHUMG00000018694 +643421 TPT1P13 HGNC:HGNC:49304 +643427 RBMS2P1 HGNC:HGNC:30994 +643432 TSG1 - +643438 LOC643438 - +643441 LOC643441 - +643445 TRIM43CP HGNC:HGNC:43981 +643446 RNPS1P1 HGNC:HGNC:39525 +643447 KRT8P49 HGNC:HGNC:48345 +643454 LOC643454 - +643459 DUSP5P2 HGNC:HGNC:44482 +643470 SURF6P1 HGNC:HGNC:37722 +643471 KRT18P12 HGNC:HGNC:33410 +643479 FAM25E HGNC:HGNC:23587 +643486 BRDTP1 HGNC:HGNC:51447|Ensembl:ENSG00000271209 +643494 LOC643494 - +643499 RPL11P5 HGNC:HGNC:36849 +643503 TARDBPP1 HGNC:HGNC:16536 +643507 RPL7P57 HGNC:HGNC:35901 +643513 KPNA2P1 HGNC:HGNC:52871 +643529 LINC00865 HGNC:HGNC:45170|Ensembl:ENSG00000232229 +643531 RPL29P26 HGNC:HGNC:35717 +643535 KCTD9P2 HGNC:HGNC:29274 +643536 VDAC1P10 HGNC:HGNC:37479 +643542 LOC643542 Ensembl:ENSG00000265533 +643550 RPL12P33 HGNC:HGNC:35696 +643554 LOC643554 - +643562 LOC643562 - +643563 EEF1A1P15 HGNC:HGNC:3198 +643576 LOC643576 - +643582 AKR1B10P2 HGNC:HGNC:45063 +643586 PKMP1 HGNC:HGNC:44243 +643596 RNF224 HGNC:HGNC:41912|Ensembl:ENSG00000233198|Vega:OTTHUMG00000187399 +643605 LOC643605 - +643609 NR1H5P MIM:617386|HGNC:HGNC:32673 +643615 UBTFL6 HGNC:HGNC:35406 +643617 RPSAP8 HGNC:HGNC:31462 +643623 LINC02523 HGNC:HGNC:53542|Ensembl:ENSG00000224506 +643627 RPS18P8 HGNC:HGNC:35956 +643630 LOC643630 - +643634 LOC643634 - +643637 GLYATL1P4 HGNC:HGNC:37864 +643641 ZNF862 HGNC:HGNC:34519|Ensembl:ENSG00000106479|Vega:OTTHUMG00000158093 +643646 HSD17B1P1 HGNC:HGNC:5216 +643648 LINC01189 HGNC:HGNC:49592 +643650 LINC00842 HGNC:HGNC:44989|Ensembl:ENSG00000264230 +643653 RPL35P8 HGNC:HGNC:36158 +643664 SLC35G6 HGNC:HGNC:31351|Ensembl:ENSG00000259224|Vega:OTTHUMG00000187017 +643668 PSMC1P9 HGNC:HGNC:39784 +643669 CCER2 HGNC:HGNC:44662|Ensembl:ENSG00000262484|Vega:OTTHUMG00000177374 +643675 LOC643675 - +643677 CCDC168 HGNC:HGNC:26851|Ensembl:ENSG00000175820|Vega:OTTHUMG00000187287 +643680 MS4A4E MIM:608401|HGNC:HGNC:14284 +643689 HNRNPA3P3 HGNC:HGNC:39772 +643699 GOLGA8N HGNC:HGNC:44405|Ensembl:ENSG00000232653|Vega:OTTHUMG00000175401 +643707 GOLGA6L4 HGNC:HGNC:27256|Ensembl:ENSG00000184206|Vega:OTTHUMG00000163050 +643709 LOC643709 - +643711 LOC643711 Ensembl:ENSG00000257501 +643714 CASC16 HGNC:HGNC:48608|Ensembl:ENSG00000249231 +643719 SCGB1B2P HGNC:HGNC:20741 +643723 LYPLAL1-AS1 HGNC:HGNC:50560 +643733 LOC643733 Ensembl:ENSG00000235505 +643739 GAPDHP31 HGNC:HGNC:37783 +643744 HMGN2P4 HGNC:HGNC:33567 +643749 TRAF3IP2-AS1 HGNC:HGNC:40005|Ensembl:ENSG00000231889 +643751 CDC42P6 HGNC:HGNC:44430 +643752 RAP1BL - +643763 UG0898H09 Ensembl:ENSG00000274956 +643766 PSMC1P6 HGNC:HGNC:39781 +643770 LINC02453 HGNC:HGNC:53392|Ensembl:ENSG00000245017 +643773 PNPLA10P HGNC:HGNC:32928 +643779 RPLP0P5 HGNC:HGNC:35620 +643783 USP46-AS1 HGNC:HGNC:43991|Ensembl:ENSG00000248866 +643784 LOC643784 - +643790 HMGN1P38 HGNC:HGNC:39422 +643802 LOC643802 - +643803 KRTAP24-1 HGNC:HGNC:33902|Ensembl:ENSG00000188694|Vega:OTTHUMG00000125483 +643812 KRTAP27-1 HGNC:HGNC:33864|Ensembl:ENSG00000206107|Vega:OTTHUMG00000059577 +643827 CNTNAP3P2 HGNC:HGNC:49589 +643831 PDCL3P2 HGNC:HGNC:31705 +643834 PGA3 MIM:169710|HGNC:HGNC:8885|Ensembl:ENSG00000229859|Vega:OTTHUMG00000168071 +643836 ZFP62 MIM:610281|HGNC:HGNC:23241|Ensembl:ENSG00000196670|Vega:OTTHUMG00000162273 +643837 LINC01128 HGNC:HGNC:49377|Ensembl:ENSG00000228794 +643847 PGA4 MIM:169720|HGNC:HGNC:8886|Ensembl:ENSG00000229183|Vega:OTTHUMG00000168073 +643851 RPL31P32 HGNC:HGNC:35719 +643853 TMPPE HGNC:HGNC:33865|Ensembl:ENSG00000188167|Vega:OTTHUMG00000155779 +643854 CTAGE9 HGNC:HGNC:37275|Ensembl:ENSG00000236761|Vega:OTTHUMG00000047966 +643855 LOC643855 - +643858 KRT18P30 HGNC:HGNC:33399 +643859 FEM1AP3 HGNC:HGNC:39831 +643862 SPDYE10P HGNC:HGNC:51506 +643863 RPL17P34 HGNC:HGNC:36756 +643865 KRT126P HGNC:HGNC:32970 +643866 CBLN3 MIM:612978|HGNC:HGNC:20146|Ensembl:ENSG00000139899|Vega:OTTHUMG00000171315 +643870 TPT1P6 HGNC:HGNC:49297 +643872 HMGN2P6 HGNC:HGNC:33574 +643873 EIF4BP7 HGNC:HGNC:37940 +643875 CNN3P1 HGNC:HGNC:38666 +643880 FKBP4P8 HGNC:HGNC:50377 +643884 SOCS5P5 HGNC:HGNC:44601 +643888 LOC643888 - +643896 LOC643896 - +643898 ARL2BPP2 HGNC:HGNC:31036 +643904 RNF222 HGNC:HGNC:34517|Ensembl:ENSG00000189051|Vega:OTTHUMG00000132049 +643905 PRR21 HGNC:HGNC:33866|Ensembl:ENSG00000221961|Vega:OTTHUMG00000159174 +643906 RPL7P27 HGNC:HGNC:36649 +643909 SPDYE9P HGNC:HGNC:45034 +643911 CRNDE MIM:615624|HGNC:HGNC:37078 +643915 MORF4L2P1 HGNC:HGNC:20403 +643916 LOC643916 - +643932 RPS3AP20 HGNC:HGNC:36141 +643941 PHKG1P1 HGNC:HGNC:33916 +643949 RPLP2P3 HGNC:HGNC:36494 +643954 RPSAP43 HGNC:HGNC:35501 +643955 ZNF733P HGNC:HGNC:32473|Ensembl:ENSG00000185037 +643960 RPS2P18 HGNC:HGNC:36449 +643965 TMEM88B HGNC:HGNC:37099|Ensembl:ENSG00000205116|Vega:OTTHUMG00000153395 +643971 RPL7P29 HGNC:HGNC:35700 +643974 RPL6P13 HGNC:HGNC:36399 +643976 FOXN3P1 HGNC:HGNC:43882 +643977 FLJ32255 - +643981 RPS3AP36 HGNC:HGNC:35596 +643987 HSFY4P HGNC:HGNC:37721 +643988 FNDC10 HGNC:HGNC:42951|Ensembl:ENSG00000228594|Vega:OTTHUMG00000154864 +643992 RPS2P26 HGNC:HGNC:36157 +643996 VDAC2P2 HGNC:HGNC:32693 +643997 LOC643997 - +644000 ARAFP2 HGNC:HGNC:647 +644006 LOC644006 - +644013 RPS6P3 HGNC:HGNC:36943 +644016 HSPD1P10 HGNC:HGNC:35131 +644017 ZNF734P HGNC:HGNC:32465 +644019 CBWD6 HGNC:HGNC:31978|Ensembl:ENSG00000215126|Vega:OTTHUMG00000067194 +644020 RPL32P23 HGNC:HGNC:36007 +644021 CTSLP3 HGNC:HGNC:2541 +644022 RPL22P19 HGNC:HGNC:36567 +644029 RPL7AP62 HGNC:HGNC:36890 +644030 KRT18P58 HGNC:HGNC:48885 +644032 PHKG1P2 HGNC:HGNC:33917 +644035 NONOP1 HGNC:HGNC:42031 +644037 HNRNPA1P12 HGNC:HGNC:39130 +644041 C18orf63 HGNC:HGNC:40037|Ensembl:ENSG00000206043|Vega:OTTHUMG00000178987 +644042 SLC25A5P6 HGNC:HGNC:512 +644050 LINC01529 HGNC:HGNC:51268|Ensembl:ENSG00000225872 +644051 LOC644051 - +644054 FAM25C HGNC:HGNC:23586|Ensembl:ENSG00000276430|Vega:OTTHUMG00000018130 +644059 PYY3 HGNC:HGNC:31855 +644060 LOC644060 - +644063 HNRNPKP4 HGNC:HGNC:42377 +644068 RPS14P3 HGNC:HGNC:35797 +644070 GSG1L2 HGNC:HGNC:51826|Ensembl:ENSG00000214978|Vega:OTTHUMG00000178429 +644076 GLYCAM1 HGNC:HGNC:18023|Ensembl:ENSG00000257780 +644079 BCRP1 HGNC:HGNC:39073 +644082 RPL18AP8 HGNC:HGNC:36984 +644083 LOC644083 - +644090 LOC644090 Ensembl:ENSG00000242048 +644093 HCG2040054 Ensembl:ENSG00000235760 +644094 PSMC1P12 HGNC:HGNC:39787 +644096 SDHAF1 MIM:612848|HGNC:HGNC:33867|Ensembl:ENSG00000205138|Vega:OTTHUMG00000181745 +644100 ARL14EPL HGNC:HGNC:44201|Ensembl:ENSG00000268223|Ensembl:ENSG00000268714|Vega:OTTHUMG00000182725 +644101 CBX3P9 HGNC:HGNC:42881 +644103 RPL29P18 HGNC:HGNC:36327 +644109 RPSAP50 HGNC:HGNC:35896 +644110 LOC644110 - +644119 RPS14P9 HGNC:HGNC:36286 +644128 RPL23AP53 HGNC:HGNC:35921 +644129 HMGB1P15 HGNC:HGNC:39097 +644131 CCT8P1 HGNC:HGNC:35144 +644135 LOC644135 - +644138 GOT2P3 HGNC:HGNC:4436 +644139 PIRT MIM:612068|HGNC:HGNC:37239|Ensembl:ENSG00000233670|Vega:OTTHUMG00000178234 +644145 EXOC1L HGNC:HGNC:53433 +644146 RPS14P8 HGNC:HGNC:37027 +644150 WIPF3 MIM:612432|HGNC:HGNC:22004|Ensembl:ENSG00000122574|Vega:OTTHUMG00000152761 +644153 DNM1P31 HGNC:HGNC:35178 +644154 RPL10AP8 HGNC:HGNC:36709 +644157 DND1P1 HGNC:HGNC:31444 +644158 LOC644158 - +644159 SLC25A1P3 HGNC:HGNC:43846 +644160 ACTG1P19 HGNC:HGNC:51499 +644165 BCRP3 HGNC:HGNC:1016 +644166 RPS26P20 HGNC:HGNC:36485 +644168 DRGX MIM:606701|HGNC:HGNC:21536|Ensembl:ENSG00000165606|Vega:OTTHUMG00000018192 +644169 LOC644169 - +644172 MAPK8IP1P2 HGNC:HGNC:52402 +644186 SYCE3 MIM:615775|HGNC:HGNC:35245|Ensembl:ENSG00000217442|Vega:OTTHUMG00000150273 +644189 LOC644189 - +644191 RPS26P8 HGNC:HGNC:31329 +644192 NR2F2-AS1 HGNC:HGNC:44222|Ensembl:ENSG00000247809 +644198 RPLP2P2 HGNC:HGNC:36590 +644202 RPL12P27 HGNC:HGNC:36916 +644203 LOC644203 - +644213 GAPDHP32 HGNC:HGNC:37784 +644214 PHBP11 HGNC:HGNC:39290 +644215 LOC644215 - +644218 TRPC6P HGNC:HGNC:23270 +644220 ACTBP11 HGNC:HGNC:33971 +644223 RPL9P4 HGNC:HGNC:23556 +644233 AURKBPS1 HGNC:HGNC:18613 +644236 RPL7AP43 HGNC:HGNC:35775 +644237 GAPDHP33 HGNC:HGNC:37785 +644242 LINC00622 HGNC:HGNC:44251|Ensembl:ENSG00000260941 +644246 KANSL1-AS1 HGNC:HGNC:43740|Ensembl:ENSG00000214401 +644248 SNCA-AS1 HGNC:HGNC:50600|Ensembl:ENSG00000247775 +644249 LOC644249 - +644253 MAPK8IP1P1 HGNC:HGNC:6885 +644256 DND1P2 HGNC:HGNC:31445 +644261 LOC644261 - +644265 LOC644265 - +644269 LOC644269 - +644277 LOC644277 - +644285 LOC644285 - +644295 LOC644295 - +644297 FAM215B HGNC:HGNC:43639 +644303 LOC644303 - +644309 RPS20P19 HGNC:HGNC:36503 +644310 LOC644310 - +644314 MT1IP MIM:156355|HGNC:HGNC:7401 +644315 RPS7P11 HGNC:HGNC:35841 +644316 FLJ43315 - +644325 ADAM20P3 HGNC:HGNC:43902 +644330 TPM3P5 HGNC:HGNC:39168 +644333 ATP5F1P3 HGNC:HGNC:39744 +644335 LOC644335 - +644338 RPL37AP8 HGNC:HGNC:35645 +644353 ZCCHC18 HGNC:HGNC:32459|Ensembl:ENSG00000166707|Vega:OTTHUMG00000022123 +644357 EEF1DP6 HGNC:HGNC:51456 +644378 GCNT6 HGNC:HGNC:21623 +644383 LOC644383 - +644384 RPL23AP71 HGNC:HGNC:36908 +644387 LOC644387 - +644388 RPS2P47 HGNC:HGNC:35785 +644390 HNRNPLP2 HGNC:HGNC:48747 +644397 LRRC37A17P HGNC:HGNC:48365 +644403 LARP1BP3 HGNC:HGNC:44085 +644414 DEFB131A HGNC:HGNC:18108|Ensembl:ENSG00000186146|Vega:OTTHUMG00000160187 +644422 LOC644422 - +644425 RARRES2P2 HGNC:HGNC:48701 +644429 HMGB3P15 HGNC:HGNC:39307 +644435 AGGF1P2 HGNC:HGNC:38052 +644436 LOC644436 - +644442 HMGB3P11 HGNC:HGNC:39303 +644444 TMEM30CP MIM:611030|HGNC:HGNC:30443|Ensembl:ENSG00000235156 +644449 HNRNPFP1 HGNC:HGNC:48812 +644451 SHQ1P1 HGNC:HGNC:45013 +644456 LOC644456 - +644459 BEND3P1 HGNC:HGNC:45014 +644462 LOC644462 - +644464 RPSAP61 HGNC:HGNC:36760 +644482 NDUFA3P3 HGNC:HGNC:45052 +644491 ICE2P1 HGNC:HGNC:48856 +644495 HSP90AB7P HGNC:HGNC:44701 +644496 CTSLP4 HGNC:HGNC:23645 +644498 HMGN2P7 HGNC:HGNC:33575 +644499 RPL39P21 HGNC:HGNC:36218 +644502 HMGB3P18 HGNC:HGNC:39310 +644509 RBM22P6 HGNC:HGNC:39699 +644511 RPL13AP6 HGNC:HGNC:23737|Ensembl:ENSG00000234118 +644517 FAM86MP HGNC:HGNC:44100 +644522 RPL31P44 HGNC:HGNC:35523 +644524 NKX2-4 MIM:607808|HGNC:HGNC:7837|Ensembl:ENSG00000125816|Vega:OTTHUMG00000032022 +644525 LOC644525 - +644534 HMGN1P11 HGNC:HGNC:39355 +644538 SMIM10 HGNC:HGNC:41913|Ensembl:ENSG00000184785|Vega:OTTHUMG00000187484 +644540 ELOCP3 HGNC:HGNC:29457 +644548 EXOC5P1 HGNC:HGNC:43870 +644554 LOC644554 - +644563 LOC644563 - +644566 TPM4P1 HGNC:HGNC:45234 +644573 SPCS2P2 HGNC:HGNC:45235 +644576 SNX18P9 HGNC:HGNC:39617 +644578 LARP1BP1 HGNC:HGNC:37097 +644584 LOC644584 - +644588 DNAJA1P3 HGNC:HGNC:39339 +644589 DNAJC19P9 HGNC:HGNC:45072 +644591 PPIAL4G HGNC:HGNC:33996|Ensembl:ENSG00000236334|Vega:OTTHUMG00000013629 +644596 SMIM10L2B HGNC:HGNC:34500|Ensembl:ENSG00000196972|Vega:OTTHUMG00000022468 +644600 GEMIN8P2 HGNC:HGNC:37977 +644601 BIN2P2 HGNC:HGNC:43661 +644604 EEF1A1P12 HGNC:HGNC:3195 +644616 ILF2P2 HGNC:HGNC:44696 +644619 INTS4P2 HGNC:HGNC:22351 +644623 TPTE2P2 HGNC:HGNC:38076 +644625 FUNDC2P3 HGNC:HGNC:37970 +644627 RPL21P107 HGNC:HGNC:36313 +644632 BMS1P11 HGNC:HGNC:49156 +644634 FAM231D HGNC:HGNC:49509 +644637 NF1P6 HGNC:HGNC:7771 +644649 APOOP5 HGNC:HGNC:48743 +644651 HMGB1P25 HGNC:HGNC:39116 +644656 LOC644656 Ensembl:ENSG00000268403 +644659 HMGB1P22 HGNC:HGNC:39107 +644660 RAD21-AS1 HGNC:HGNC:32158|Ensembl:ENSG00000253327 +644661 LOC644661 - +644667 LOC644667 - +644669 LOC644669 Ensembl:ENSG00000215512 +644672 CLDN25 HGNC:HGNC:37218|Ensembl:ENSG00000228607|Vega:OTTHUMG00000168193 +644681 LOC644681 - +644684 BMS1P12 HGNC:HGNC:49157 +644694 CDRT15P2 HGNC:HGNC:34074 +644714 LIMD1-AS1 HGNC:HGNC:44107 +644716 BMS1P13 HGNC:HGNC:49158 +644717 SAGE2P HGNC:HGNC:51337 +644721 LOC644721 - +644731 IGKV1OR-3 HGNC:HGNC:5762|IMGT/GENE-DB:IGKV1/OR-3 +644739 WASF4P HGNC:HGNC:20801 +644743 KRT8P47 HGNC:HGNC:44461 +644745 HSPD1P4 HGNC:HGNC:35146 +644746 LOC644746 - +644754 BOLA3P3 HGNC:HGNC:51442 +644758 PABPC1P13 HGNC:HGNC:37995 +644759 TMPRSS11GP HGNC:HGNC:42983|Ensembl:ENSG00000229009 +644761 PIGHP1 HGNC:HGNC:45152 +644762 LOC644762 - +644768 SLC9B1P4 HGNC:HGNC:43583 +644773 ACTR3BP6 HGNC:HGNC:38683 +644776 LOC644776 - +644777 MEP1AP2 HGNC:HGNC:7017 +644790 RPS15AP11 HGNC:HGNC:36707 +644794 LOC644794 - +644809 C15orf56 HGNC:HGNC:33868 +644815 FAM83G MIM:615886|HGNC:HGNC:32554|Ensembl:ENSG00000188522|Vega:OTTHUMG00000059411 +644820 EEF1B2P3 HGNC:HGNC:3210 +644834 RPL36AP36 HGNC:HGNC:36326 +644838 LINC01829 HGNC:HGNC:52635|Ensembl:ENSG00000236780 +644844 PHGR1 HGNC:HGNC:37226|Ensembl:ENSG00000233041|Vega:OTTHUMG00000172416 +644850 PDCL3P5 HGNC:HGNC:44506 +644861 NBPF13P HGNC:HGNC:31995 +644862 RPS28P3 HGNC:HGNC:36589 +644871 TRAF6P1 HGNC:HGNC:45032 +644873 LINC01184 HGNC:HGNC:49565|Ensembl:ENSG00000245937 +644877 CACYBPP2 HGNC:HGNC:45123 +644881 RARRES2P4 HGNC:HGNC:48703 +644890 MEIG1 MIM:614174|HGNC:HGNC:23429|Ensembl:ENSG00000197889|Vega:OTTHUMG00000017717 +644893 LOC644893 - +644896 RPL7P7 HGNC:HGNC:36895 +644899 TERF2IPP1 HGNC:HGNC:19258 +644903 GCC2-AS1 HGNC:HGNC:28126|Ensembl:ENSG00000214184 +644906 LOC644906 - +644907 RPL32P18 HGNC:HGNC:36301 +644909 LOC644909 - +644911 RPL10P5 HGNC:HGNC:35724 +644914 H3F3AP6 HGNC:HGNC:42982 +644915 METTL15P2 HGNC:HGNC:39559 +644919 LINC02315 HGNC:HGNC:53234 +644924 LOC644924 - +644928 RPS26P15 HGNC:HGNC:35680 +644934 RPS26P50 HGNC:HGNC:35615 +644935 ELF2P4 HGNC:HGNC:33540 +644936 LOC644936 - +644937 RPL10P8 HGNC:HGNC:52344 +644943 RASSF10 MIM:614713|HGNC:HGNC:33984|Ensembl:ENSG00000189431|Vega:OTTHUMG00000166184 +644945 KRT16P3 HGNC:HGNC:37808|Ensembl:ENSG00000214822 +644961 ACTG1P20 HGNC:HGNC:51500 +644962 TNRC18P1 HGNC:HGNC:43881 +644972 RPS3AP26 HGNC:HGNC:36513 +644974 ALG1L2 HGNC:HGNC:37258|Ensembl:ENSG00000251287|Vega:OTTHUMG00000159782 +644988 ABHD17AP6 HGNC:HGNC:34044 +644990 THRB-AS1 HGNC:HGNC:44515 +644994 SMIM23 HGNC:HGNC:34440|Ensembl:ENSG00000185662 +644996 RPL32P22 HGNC:HGNC:36694 +644997 PIK3CD-AS1 HGNC:HGNC:32346|Ensembl:ENSG00000179840 +644998 KRT8P19 HGNC:HGNC:33371 +645000 RPS3P6 HGNC:HGNC:36061 +645001 HNRNPA1P52 HGNC:HGNC:48782 +645015 ALG1L8P HGNC:HGNC:44377 +645018 RPS2P20 HGNC:HGNC:35992 +645024 GAPDHP59 HGNC:HGNC:4152 +645027 EVPLL HGNC:HGNC:35236|Ensembl:ENSG00000214860|Vega:OTTHUMG00000059095 +645030 NFIA-AS1 HGNC:HGNC:40402|Ensembl:ENSG00000237853 +645037 GAGE2B MIM:300726|HGNC:HGNC:31957 +645051 GAGE13 MIM:300734|HGNC:HGNC:29081|Ensembl:ENSG00000274274|Vega:OTTHUMG00000024138 +645054 RPL6P4 HGNC:HGNC:36344 +645065 RPEP2 HGNC:HGNC:44521 +645073 GAGE12G MIM:300731|HGNC:HGNC:31907|Ensembl:ENSG00000215269|Vega:OTTHUMG00000024148 +645078 ZCCHC23 HGNC:HGNC:32963 +645084 DBF4P1 HGNC:HGNC:45059 +645086 LOC645086 - +645094 MYL12BP1 HGNC:HGNC:51649 +645104 CLRN2 HGNC:HGNC:33939|Ensembl:ENSG00000249581|Vega:OTTHUMG00000160273 +645108 NACAP5 HGNC:HGNC:49492 +645120 AIFM1P1 HGNC:HGNC:44884 +645121 CCNI2 HGNC:HGNC:33869|Ensembl:ENSG00000205089|Vega:OTTHUMG00000059737 +645126 PFN1P6 HGNC:HGNC:42988 +645129 ZBTB45P1 HGNC:HGNC:49227 +645135 LOC645135 - +645136 MYCLP2 HGNC:HGNC:48924 +645139 LOC645139 - +645142 PPIAL4D HGNC:HGNC:33998|Ensembl:ENSG00000256374|Vega:OTTHUMG00000078265 +645145 ZBED1P1 HGNC:HGNC:44004 +645157 RPL21P61 HGNC:HGNC:36712 +645158 CBX3P2 HGNC:HGNC:42874|Ensembl:ENSG00000266405 +645160 RPL5P30 HGNC:HGNC:35837 +645161 RPL12P8 HGNC:HGNC:23735 +645163 LOC645163 - +645166 LOC645166 - +645173 RPS2P48 HGNC:HGNC:35985 +645174 RPL21P46 HGNC:HGNC:35687 +645175 MEMO1P2 HGNC:HGNC:38502 +645177 LOC645177 - +645180 LOC645180 - +645181 LOC645181 - +645188 LOC645188 - +645191 LINGO3 MIM:609792|HGNC:HGNC:21206|Ensembl:ENSG00000220008|Vega:OTTHUMG00000180418 +645201 HMGB1P26 HGNC:HGNC:39117 +645202 LOC645202 - +645203 TMEM14DP HGNC:HGNC:15660 +645204 HNRNPMP1 HGNC:HGNC:48745 +645206 LINC00693 HGNC:HGNC:44526 +645207 EIF4E2P2 HGNC:HGNC:51464 +645212 EIF3J-AS1 HGNC:HGNC:48616 +645220 ADIPOR1P1 HGNC:HGNC:44910 +645224 RPL29P17 HGNC:HGNC:36910 +645233 TDGP1 HGNC:HGNC:49891 +645249 MNX1-AS1 HGNC:HGNC:48954|Ensembl:ENSG00000243479 +645251 CBX1P1 HGNC:HGNC:38655 +645256 GAPDHP66 HGNC:HGNC:4144 +645257 RPL7AP37 HGNC:HGNC:36507 +645261 LOC645261 - +645264 OSTCP4 HGNC:HGNC:42866 +645266 LOC645266 - +645269 TMEM256P1 HGNC:HGNC:45087 +645272 LOC645272 - +645280 SMPD4P1 HGNC:HGNC:39673 +645292 HMGB1P6 HGNC:HGNC:4998 +645296 RPL17P39 HGNC:HGNC:36427 +645297 LOC645297 - +645299 RPS10P24 HGNC:HGNC:35989 +645311 EEF1GP7 HGNC:HGNC:44562 +645312 GLTPP1 HGNC:HGNC:33991 +645313 SCDP1 HGNC:HGNC:10572 +645314 LOC645314 - +645317 CHCHD2P6 HGNC:HGNC:39590 +645318 PHB2P1 HGNC:HGNC:45249 +645319 LOC645319 - +645321 LINC01896 HGNC:HGNC:52715 +645323 LINC00461 MIM:616611|HGNC:HGNC:42810|Ensembl:ENSG00000245526 +645324 LOC645324 - +645326 RPSAP11 HGNC:HGNC:6503 +645328 MRPL40P1 HGNC:HGNC:44532 +645332 FAM86C2P HGNC:HGNC:42392|Ensembl:ENSG00000160172 +645339 SNRPD2P2 HGNC:HGNC:38598 +645345 CHCHD2P9 HGNC:HGNC:23676 +645348 TUBA3GP HGNC:HGNC:44096 +645354 PRAMEF36P HGNC:HGNC:51897 +645355 MIR3976HG HGNC:HGNC:51104|Ensembl:ENSG00000261738 +645357 LOC645357 - +645359 PRAMEF26 HGNC:HGNC:49178|Ensembl:ENSG00000280267|Vega:OTTHUMG00000009499 +645360 HMGB3P5 HGNC:HGNC:39105 +645367 GGT8P HGNC:HGNC:33438 +645368 EIF3KP3 HGNC:HGNC:44018 +645369 TMEM200C HGNC:HGNC:37208|Ensembl:ENSG00000206432|Vega:OTTHUMG00000178423 +645373 RPL21P76 HGNC:HGNC:37042 +645381 TLE1P1 HGNC:HGNC:39438 +645382 PRAMEF33 HGNC:HGNC:49193|Ensembl:ENSG00000237700 +645387 RPL6P27 HGNC:HGNC:36133 +645388 LOC645388 - +645397 LOC645397 - +645398 NIFKP2 HGNC:HGNC:44950 +645402 USP17L4 HGNC:HGNC:37176|Ensembl:ENSG00000236125|Vega:OTTHUMG00000150574 +645405 LOC645405 - +645412 RPS16P9 HGNC:HGNC:35659 +645414 PRAMEF19 HGNC:HGNC:24908|Ensembl:ENSG00000204480|Vega:OTTHUMG00000007919 +645415 LOC645415 - +645422 RPL10P12 HGNC:HGNC:52345 +645423 SLC25A51P2 HGNC:HGNC:23327 +645425 PRAMEF20 HGNC:HGNC:25224|Ensembl:ENSG00000204478|Vega:OTTHUMG00000007911 +645426 TMEM191C HGNC:HGNC:33601|Ensembl:ENSG00000206140 +645431 FUT8-AS1 HGNC:HGNC:44294 +645432 ARRDC5 HGNC:HGNC:31407|Ensembl:ENSG00000205784|Vega:OTTHUMG00000180250 +645433 LOC645433 - +645434 LINC01625 HGNC:HGNC:52052|Ensembl:ENSG00000238099 +645436 HNRNPA1P63 HGNC:HGNC:48793 +645440 ATP5F1P6 HGNC:HGNC:39747 +645441 RPL17P6 HGNC:HGNC:36520 +645443 ATP5A1P3 HGNC:HGNC:829 +645452 RPL21P68 HGNC:HGNC:35720 +645453 RLIMP3 HGNC:HGNC:39684 +645455 CEP170P1 HGNC:HGNC:28364 +645468 LOC645468 - +645474 S100A11P3 HGNC:HGNC:37842 +645481 LOC645481 - +645482 LOC645482 - +645485 LOC645485 Ensembl:ENSG00000246331 +645486 AHCYP7 HGNC:HGNC:44999 +645506 GYG1P3 HGNC:HGNC:39711 +645513 LOC645513 Ensembl:ENSG00000245958 +645520 FAM138A HGNC:HGNC:32334|Ensembl:ENSG00000237613 +645528 FAM238A HGNC:HGNC:17776|Ensembl:ENSG00000233261 +645529 LOC645529 - +645538 GOT2P1 HGNC:HGNC:4434 +645544 LOC645544 - +645545 IGBP1P2 HGNC:HGNC:43611 +645548 HSPD1P6 HGNC:HGNC:5267 +645553 IGFL2-AS1 HGNC:HGNC:52559 +645558 FAM90A22P HGNC:HGNC:32270 +645560 ATP5C1P1 HGNC:HGNC:834 +645571 PRADC1P1 HGNC:HGNC:44534 +645572 FAM90A23P HGNC:HGNC:32271 +645573 RPS4XP19 HGNC:HGNC:36872 +645579 EIF4BP6 HGNC:HGNC:37939 +645587 LINC00614 HGNC:HGNC:30165 +645591 LHFPL3-AS1 HGNC:HGNC:40341|Ensembl:ENSG00000226869 +645598 WIZP1 HGNC:HGNC:51696 +645619 AK4P3 HGNC:HGNC:21596 +645630 RPS13P8 HGNC:HGNC:36400 +645638 WFDC21P MIM:615772|HGNC:HGNC:50357|Ensembl:ENSG00000261040 +645641 MESTP3 HGNC:HGNC:38553 +645644 FLJ42627 - +645646 FAM32CP HGNC:HGNC:34239 +645651 FAM90A14P MIM:613050|HGNC:HGNC:32262 +645652 MT1XP1 HGNC:HGNC:7442 +645654 RPL31P48 HGNC:HGNC:36129 +645656 RPSAP56 HGNC:HGNC:36018 +645668 TUFMP1 HGNC:HGNC:12421 +645676 ASH1L-AS1 HGNC:HGNC:44146 +645680 KPNA2P2 HGNC:HGNC:52872 +645682 POU5F1P4 HGNC:HGNC:33310|Ensembl:ENSG00000237872 +645683 RPL13AP3 HGNC:HGNC:23539|Ensembl:ENSG00000177350 +645686 GTF2IP3 HGNC:HGNC:42640 +645687 LINC00520 HGNC:HGNC:19843 +645688 RPL12P38 HGNC:HGNC:36838 +645691 HNRNPA1P35 HGNC:HGNC:48764 +645693 EEF1A1P22 HGNC:HGNC:37895 +645694 HTR5BP HGNC:HGNC:16291 +645700 ZNF890P HGNC:HGNC:38691|Ensembl:ENSG00000159904 +645713 RPS10P23 HGNC:HGNC:36657 +645715 EEF1A1P24 HGNC:HGNC:37897 +645740 NOS2P1 MIM:600720|HGNC:HGNC:7875 +645744 TAF5LP1 HGNC:HGNC:24115 +645745 MT1HL1 HGNC:HGNC:31864|Ensembl:ENSG00000244020|Vega:OTTHUMG00000040065 +645749 LOC645749 - +645752 LOC645752 - +645754 LGALS9DP HGNC:HGNC:49896 +645763 LOC645763 - +645771 PARP4P2 HGNC:HGNC:37760 +645773 LOC645773 - +645784 ANKRD36BP2 HGNC:HGNC:33607|Ensembl:ENSG00000230006 +645798 RPL3P3 HGNC:HGNC:23550 +645805 DAZAP2P1 HGNC:HGNC:43869 +645807 RPL5P10 HGNC:HGNC:36846 +645808 HSPD1P2 HGNC:HGNC:5263 +645809 RPL23AP56 HGNC:HGNC:35516 +645811 CCDC154 HGNC:HGNC:34454|Ensembl:ENSG00000197599 +645832 SEBOX MIM:610975|HGNC:HGNC:32942|Ensembl:ENSG00000274529|Vega:OTTHUMG00000171160 +645834 KRT8P15 HGNC:HGNC:33367 +645836 USP17L3 HGNC:HGNC:37175|Ensembl:ENSG00000225327|Vega:OTTHUMG00000165406 +645840 TXNRD3NB HGNC:HGNC:33870|Ensembl:ENSG00000206483|Ensembl:ENSG00000283374|Vega:OTTHUMG00000162732 +645841 TMEM248P1 HGNC:HGNC:44053 +645843 TMEM14EP HGNC:HGNC:34386|Ensembl:ENSG00000221962 +645846 RPL7AP58 HGNC:HGNC:36586 +645852 LOC645852 - +645853 LOC645853 - +645857 RPS10P17 HGNC:HGNC:35562 +645859 CCDC58P1 HGNC:HGNC:32457 +645862 CHCHD4P1 HGNC:HGNC:44489 +645864 MAGEB17 MIM:300763|HGNC:HGNC:17418|Ensembl:ENSG00000182798|Vega:OTTHUMG00000021188 +645877 LOC645877 - +645879 FAM90A12P MIM:613048|HGNC:HGNC:32260 +645884 RPS7P5 HGNC:HGNC:37037 +645899 RPS28P4 HGNC:HGNC:36208 +645900 LAPTM4BP1 HGNC:HGNC:51934 +645916 RPS11P2 HGNC:HGNC:37007 +645918 RPS13P7 HGNC:HGNC:36310 +645922 S100A7L2 HGNC:HGNC:21655|Ensembl:ENSG00000197364|Vega:OTTHUMG00000013129 +645927 MCFD2P1 HGNC:HGNC:21582 +645930 HMGN2P31 HGNC:HGNC:39398 +645931 FEN1P1 HGNC:HGNC:3651 +645937 LOC645937 - +645938 LOC645938 - +645939 THAP12P8 HGNC:HGNC:39572 +645940 HNRNPA1P32 HGNC:HGNC:44958 +645949 LINC01822 HGNC:HGNC:52627|Ensembl:ENSG00000229621 +645950 HNRNPA1P1 HGNC:HGNC:13957 +645954 SVILP1 HGNC:HGNC:44959 +645957 RPS3P7 HGNC:HGNC:36056 +645958 RPS18P9 HGNC:HGNC:36483 +645960 RPL10P19 HGNC:HGNC:52350 +645961 SPATA31C2 HGNC:HGNC:24508 +645962 RPL23AP20 HGNC:HGNC:36622 +645965 LOC645965 - +645967 LOC645967 Ensembl:ENSG00000278899 +645968 RPS3AP25 HGNC:HGNC:36801 +645969 LOC645969 - +645973 ATP5F1P2 HGNC:HGNC:39743 +645974 PABPC1L2B HGNC:HGNC:31852|Ensembl:ENSG00000184388|Vega:OTTHUMG00000021823 +645978 LOC645978 - +645979 RPS26P31 HGNC:HGNC:36614 +645980 CFL1P4 HGNC:HGNC:1880 +645993 RPL31P57 HGNC:HGNC:35703 +645996 NAP1L6 HGNC:HGNC:31706|Ensembl:ENSG00000204118|Vega:OTTHUMG00000021826 +645998 RPL10AP5 HGNC:HGNC:36770 +646000 SLC35G4 HGNC:HGNC:31043|Ensembl:ENSG00000236396|Vega:OTTHUMG00000180598 +646012 LOC646012 - +646013 RPS17P3 HGNC:HGNC:10399 +646016 YWHAZP8 HGNC:HGNC:39029 +646019 CBY3 HGNC:HGNC:33278|Ensembl:ENSG00000204659|Vega:OTTHUMG00000163163 +646023 ADORA2A-AS1 HGNC:HGNC:37122|Ensembl:ENSG00000178803 +646024 RAET1K HGNC:HGNC:16797|Ensembl:ENSG00000218358 +646029 LOC646029 - +646030 LOC646030 - +646034 LOC646034 - +646044 LOC646044 - +646049 HMGN2P20 HGNC:HGNC:39385 +646050 LOC646050 - +646052 SLC20A1P3 HGNC:HGNC:42538 +646058 LOC646058 - +646065 PMM2P2 HGNC:HGNC:21753 +646066 LOC646066 - +646070 CICP18 HGNC:HGNC:48828 +646071 LOC646071 - +646074 POM121L10P HGNC:HGNC:35448 +646077 RPL29P23 HGNC:HGNC:35946 +646080 RAB11FIP1P1 HGNC:HGNC:42366 +646083 PA2G4P6 HGNC:HGNC:32219 +646085 PSMC1P7 HGNC:HGNC:39782 +646086 WDR45BP1 HGNC:HGNC:26605 +646087 IMP3P1 HGNC:HGNC:49385 +646090 RHPN2P1 HGNC:HGNC:37708 +646093 RPS8P7 HGNC:HGNC:35795 +646096 CHEK2P2 HGNC:HGNC:43578|Ensembl:ENSG00000259156 +646103 LOC646103 - +646104 RPL32P16 HGNC:HGNC:36086 +646108 RPS7P14 HGNC:HGNC:36602 +646112 LOC646112 - +646113 LINC00643 HGNC:HGNC:44296 +646114 AKAP8P1 HGNC:HGNC:49758 +646119 RPS8P4 HGNC:HGNC:17478 +646120 LOC646120 - +646127 LOC646127 - +646140 LOC646140 - +646161 RPL26P21 HGNC:HGNC:35497 +646164 DDX39AP1 HGNC:HGNC:39664 +646168 LRRC77P HGNC:HGNC:50536|Ensembl:ENSG00000244227 +646171 EIF4A2P1 HGNC:HGNC:37929 +646174 C16orf90 HGNC:HGNC:34455|Ensembl:ENSG00000215131|Vega:OTTHUMG00000154627 +646175 RPL36AP48 HGNC:HGNC:36721 +646177 SPATA31E2P HGNC:HGNC:43827 +646189 RPL18AP13 HGNC:HGNC:36739 +646192 NOP56P1 HGNC:HGNC:13962 +646193 TRAPPC13P1 HGNC:HGNC:50347 +646195 RPS28P7 HGNC:HGNC:35787 +646196 SMARCE1P6 HGNC:HGNC:39737 +646197 LOC646197 - +646201 BASP1P1 HGNC:HGNC:39418 +646202 TLK2P1 HGNC:HGNC:18048 +646203 LOC646203 - +646208 NUS1P2 HGNC:HGNC:38473 +646213 SS18L2P1 HGNC:HGNC:44965 +646214 LOC646214 - +646216 LOC646216 - +646218 PRDX2P2 HGNC:HGNC:44967 +646227 LOC646227 - +646231 AGPAT5P1 HGNC:HGNC:37709 +646233 RPS27P10 HGNC:HGNC:35961 +646241 LINC02223 HGNC:HGNC:53092 +646243 CXADRP2 HGNC:HGNC:33973 +646249 PCED1CP HGNC:HGNC:44083 +646255 RPL19P16 HGNC:HGNC:36596 +646260 SAR1AP1 HGNC:HGNC:13983 +646262 LACTBL1 HGNC:HGNC:35445|Ensembl:ENSG00000215906|Vega:OTTHUMG00000003228 +646268 LINC01704 HGNC:HGNC:52492|Ensembl:ENSG00000231666 +646269 RPS4XP8 HGNC:HGNC:36683 +646270 ELL2P1 HGNC:HGNC:39343 +646273 HSPD1P15 HGNC:HGNC:35130 +646274 LOC646274 - +646278 PDCD6IPP2 HGNC:HGNC:49873 +646282 AZGP1P1 HGNC:HGNC:911|Ensembl:ENSG00000214313 +646294 RPS2P29 HGNC:HGNC:36011 +646300 COL6A4P2 MIM:616612|HGNC:HGNC:38501 +646309 NAMPTP1 HGNC:HGNC:17633 +646316 TERF1P3 HGNC:HGNC:38499 +646324 LINC00607 HGNC:HGNC:43944|Ensembl:ENSG00000235770 +646330 BTBD6P1 HGNC:HGNC:51542 +646346 RPL7P58 HGNC:HGNC:49214 +646347 LOC646347 - +646348 ARL6IP1P2 HGNC:HGNC:44971 +646358 LOC646358 - +646359 TERF1P2 HGNC:HGNC:38110 +646360 TMEM161BP1 HGNC:HGNC:44973 +646362 FTH1P13 HGNC:HGNC:3983 +646366 MAS1LP1 HGNC:HGNC:33448 +646370 IGHV1OR15-3 HGNC:HGNC:5565|IMGT/GENE-DB:IGHV1/OR15-3 +646377 PYHIN5P HGNC:HGNC:51820 +646378 DDX18P5 HGNC:HGNC:33968 +646379 IGHV1OR15-4 HGNC:HGNC:5566|IMGT/GENE-DB:IGHV1/OR15-4 +646382 DPPA5P1 HGNC:HGNC:43752 +646383 LOC646383 - +646388 LOC646388 - +646390 IRX1P1 HGNC:HGNC:33315 +646392 NIP7P2 HGNC:HGNC:45181 +646396 REREP3 HGNC:HGNC:38797 +646405 TPTE2P1 HGNC:HGNC:35196 +646408 LOC646408 - +646409 DGAT2L7P HGNC:HGNC:44367 +646417 RPL29P5 HGNC:HGNC:36786 +646424 SPINK8 HGNC:HGNC:33160|Ensembl:ENSG00000229453|Vega:OTTHUMG00000156832 +646430 LOC646430 - +646433 RPL32P19 HGNC:HGNC:36743 +646440 CCT3P1 HGNC:HGNC:35129 +646442 SNX19P3 HGNC:HGNC:38116 +646446 RPL27P2 HGNC:HGNC:36948 +646450 ARIH2OS HGNC:HGNC:34425|Ensembl:ENSG00000221883|Vega:OTTHUMG00000156672 +646457 C19orf67 HGNC:HGNC:34354|Ensembl:ENSG00000188032|Vega:OTTHUMG00000169303 +646463 UBE2HP1 HGNC:HGNC:31079 +646467 CNN2P1 HGNC:HGNC:39526 +646471 LOC646471 - +646476 RPL7AP39 HGNC:HGNC:35881 +646479 ADAM24P HGNC:HGNC:203 +646480 FABP9 HGNC:HGNC:3563|Ensembl:ENSG00000205186|Vega:OTTHUMG00000164601 +646483 RPL6P19 HGNC:HGNC:36754 +646486 FABP12 HGNC:HGNC:34524|Ensembl:ENSG00000197416|Vega:OTTHUMG00000164679 +646489 RPL21P70 HGNC:HGNC:37024 +646498 C3orf84 HGNC:HGNC:44666|Ensembl:ENSG00000236980|Vega:OTTHUMG00000156816 +646505 CLK3P1 HGNC:HGNC:49785 +646506 LOC646506 - +646507 SPATA31E3P HGNC:HGNC:43828 +646508 FAM90A27P HGNC:HGNC:43617|Ensembl:ENSG00000189348 +646517 LOC646517 - +646520 SUCLA2P1 HGNC:HGNC:21632 +646522 LOC646522 Ensembl:ENSG00000255258 +646526 HMGB1P18 HGNC:HGNC:39100 +646527 RPS3AP44 HGNC:HGNC:36761 +646531 YBX1P2 HGNC:HGNC:22635 +646532 RPL19P5 HGNC:HGNC:36325 +646535 LOC646535 - +646538 RPL7P10 HGNC:HGNC:36599 +646548 LOC646548 - +646555 LOC646555 - +646557 OSTCP3 HGNC:HGNC:42865 +646566 RPLP1P12 HGNC:HGNC:36858 +646567 OSTCP2 HGNC:HGNC:42864 +646572 CHCHD3P3 HGNC:HGNC:44699 +646575 CYP4F10P HGNC:HGNC:39943 +646576 HHIP-AS1 HGNC:HGNC:44182|Ensembl:ENSG00000248890 +646577 HMGB1P16 HGNC:HGNC:39098 +646581 IFNWP2 HGNC:HGNC:5452 +646583 RPS4XP18 HGNC:HGNC:36170 +646588 LOC646588 Ensembl:ENSG00000223561 +646592 ZNF652P1 HGNC:HGNC:35166 +646595 UBE2CP2 HGNC:HGNC:43551 +646597 CHMP1AP1 HGNC:HGNC:39514 +646600 IGF2BP2-AS1 HGNC:HGNC:32674|Ensembl:ENSG00000163915 +646603 C4orf51 HGNC:HGNC:37264|Ensembl:ENSG00000237136|Vega:OTTHUMG00000161367 +646609 CLIC4P1 HGNC:HGNC:49797 +646612 EEF1A1P25 HGNC:HGNC:37898 +646614 BUB3P1 HGNC:HGNC:51559 +646616 LOC646616 - +646619 ATP5G1P3 HGNC:HGNC:39506 +646620 RPL3P8 HGNC:HGNC:35498 +646624 RPL27P4 HGNC:HGNC:35503 +646625 URAD MIM:615804|HGNC:HGNC:17785|Ensembl:ENSG00000183463|Vega:OTTHUMG00000186217 +646626 LOC646626 - +646627 LYPD8 MIM:617067|HGNC:HGNC:44208|Ensembl:ENSG00000259823|Vega:OTTHUMG00000174833 +646629 LOC646629 - +646630 CHCHD2P8 HGNC:HGNC:39592 +646639 LOC646639 - +646640 TTC39DP HGNC:HGNC:35451 +646641 RPL7L1P7 HGNC:HGNC:39489 +646643 SBK2 HGNC:HGNC:34416|Ensembl:ENSG00000187550|Vega:OTTHUMG00000155830 +646644 LOC646644 - +646652 LOC646652 - +646658 SYNDIG1L MIM:609999|HGNC:HGNC:32388|Ensembl:ENSG00000183379|Vega:OTTHUMG00000171210 +646660 RPS20P26 HGNC:HGNC:36980 +646663 RFPL4AP1 HGNC:HGNC:45138 +646665 LOC646665 - +646666 LOC646666 - +646670 LOC646670 - +646672 RPL15P20 HGNC:HGNC:36130 +646674 LOC646674 - +646685 RPL23AP41 HGNC:HGNC:35634 +646688 RPL4P2 HGNC:HGNC:36836 +646693 CNN2P10 HGNC:HGNC:39535 +646696 LOC646696 - +646698 ZSCAN5DP HGNC:HGNC:37706 +646700 LOC646700 - +646701 DPPA5P4 HGNC:HGNC:49665 +646702 HLA-DPA2 HGNC:HGNC:4939 +646708 LOC646708 - +646709 LOC646709 - +646710 RPL19P4 HGNC:HGNC:36539 +646719 NIPBL-AS1 HGNC:HGNC:51293 +646721 FAM60DP HGNC:HGNC:19896 +646723 KRT18P31 HGNC:HGNC:33400 +646730 LOC646730 - +646736 LOC646736 - +646737 RPS14P6 HGNC:HGNC:36241 +646743 LOC646743 - +646745 LOC646745 - +646753 RPS26P2 HGNC:HGNC:23662 +646754 TRIM64C HGNC:HGNC:37148|Ensembl:ENSG00000214891|Vega:OTTHUMG00000166752 +646755 MFAP1P1 HGNC:HGNC:39694 +646758 PTPN2P2 HGNC:HGNC:9654 +646759 UBTFL7 HGNC:HGNC:35404 +646762 LOC646762 - +646766 RPL35P2 HGNC:HGNC:35789 +646770 TRIM77BP HGNC:HGNC:43980 +646780 PHKA1P1 HGNC:HGNC:33919 +646784 RPL5P6 HGNC:HGNC:35890 +646785 RPS10P13 HGNC:HGNC:36374 +646787 RPL31P37 HGNC:HGNC:36197 +646791 ANP32BP1 HGNC:HGNC:24267 +646794 LOC646794 - +646797 LOC646797 - +646799 ZAR1L HGNC:HGNC:37116|Ensembl:ENSG00000189167|Vega:OTTHUMG00000016694 +646801 LOC646801 - +646802 CYP4F62P HGNC:HGNC:39956|Ensembl:ENSG00000239402 +646804 LOC646804 - +646808 LAGE3P1 HGNC:HGNC:49909 +646813 LOC646813 - +646817 SETSIP HGNC:HGNC:42937|Ensembl:ENSG00000230667|Vega:OTTHUMG00000010287 +646819 RPS15AP19 HGNC:HGNC:36603 +646820 RPL19P19 HGNC:HGNC:36194 +646828 LOC646828 - +646837 EEF1GP1 HGNC:HGNC:44556 +646839 TPM3P8 HGNC:HGNC:39171 +646849 NPM1P28 HGNC:HGNC:45207 +646851 FAM227A HGNC:HGNC:44197|Ensembl:ENSG00000184949|Vega:OTTHUMG00000151133 +646853 LOC646853 - +646862 RNF225 HGNC:HGNC:51249|Ensembl:ENSG00000269855|Vega:OTTHUMG00000189258 +646864 ZNF723 HGNC:HGNC:32286 +646870 LOC646870 - +646873 PRELID3BP10 HGNC:HGNC:49072 +646875 RPL12P2 HGNC:HGNC:16070 +646877 GAPDHP34 HGNC:HGNC:37786 +646879 ARL2BPP3 HGNC:HGNC:39447 +646884 RPL29P28 HGNC:HGNC:36842 +646890 LOC646890 - +646891 SDCCAG3P2 HGNC:HGNC:39164 +646892 SH2D7 HGNC:HGNC:34549|Ensembl:ENSG00000183476|Vega:OTTHUMG00000154271 +646898 RPL12P40 HGNC:HGNC:36439 +646903 LOC646903 - +646909 RPL17P33 HGNC:HGNC:36654 +646910 HSPD1P9 HGNC:HGNC:35132 +646912 RPL7P52 HGNC:HGNC:35676 +646913 SEPT7P3 HGNC:HGNC:38038 +646915 ZNF806 HGNC:HGNC:33228 +646927 LOC646927 - +646929 ANKRD26P2 HGNC:HGNC:39687 +646934 LOC646934 - +646936 CTBP2P5 HGNC:HGNC:45197 +646938 LOC646938 Ensembl:ENSG00000238166 +646942 RPS10P14 HGNC:HGNC:35880 +646949 RPL23P6 HGNC:HGNC:35554 +646951 MINDY4B HGNC:HGNC:35475 +646954 YWHAQP4 HGNC:HGNC:37683 +646956 HNRNPCP3 HGNC:HGNC:48815 +646960 PRSS56 MIM:613858|HGNC:HGNC:39433|Ensembl:ENSG00000237412|Vega:OTTHUMG00000153326 +646962 HRCT1 HGNC:HGNC:33872|Ensembl:ENSG00000196196|Vega:OTTHUMG00000154146 +646966 RPL26P16 HGNC:HGNC:36098 +646970 LOC646970 - +646976 LOC646976 - +646981 PTPN2P1 HGNC:HGNC:9653 +646982 LINC00598 HGNC:HGNC:42770|Ensembl:ENSG00000215483 +646985 RPS12P25 HGNC:HGNC:36019 +646993 HMGB3P24 HGNC:HGNC:39316 +646995 LOC646995 - +646996 RAB42P1 HGNC:HGNC:19799 +646999 LOC646999 - +647000 TUBBP2 HGNC:HGNC:12415 +647001 GAPDHP35 HGNC:HGNC:37789 +647002 LOC647002 - +647009 RWDD4P2 HGNC:HGNC:23754 +647012 YY1P2 HGNC:HGNC:45095 +647013 KCTD9P3 HGNC:HGNC:49912 +647015 CDC37P2 HGNC:HGNC:35453 +647016 EIF2S2P7 HGNC:HGNC:37795 +647024 C6orf132 HGNC:HGNC:21288|Ensembl:ENSG00000188112|Vega:OTTHUMG00000014695 +647030 EEF1B2P6 HGNC:HGNC:51453 +647033 PA2G4P4 HGNC:HGNC:32217 +647034 RPS14P10 HGNC:HGNC:35517 +647042 GOLGA6L10 HGNC:HGNC:37228|Ensembl:ENSG00000278662|Vega:OTTHUMG00000172580 +647044 FAM220BP HGNC:HGNC:23678 +647047 TCP1P1 HGNC:HGNC:11659 +647051 YWHABP1 HGNC:HGNC:50294 +647060 SPATA31A1 HGNC:HGNC:23394|Ensembl:ENSG00000204849|Vega:OTTHUMG00000013156 +647070 LOC647070 - +647076 BRD7P2 HGNC:HGNC:33541 +647077 LOC647077 - +647081 SDHDP2 HGNC:HGNC:10685 +647085 PPIAP25 HGNC:HGNC:39270 +647086 LOC647086 - +647087 C7orf73 HGNC:HGNC:41909|Ensembl:ENSG00000243317|Vega:OTTHUMG00000155495 +647094 RPLP0P11 HGNC:HGNC:36572 +647099 RPL23AP42 HGNC:HGNC:35942 +647102 ELK1P1 HGNC:HGNC:39021 +647107 LINC01192 HGNC:HGNC:37197|Ensembl:ENSG00000241369 +647112 RPL27P6 HGNC:HGNC:36330 +647115 LOC647115 - +647121 EMBP1 HGNC:HGNC:38661|Ensembl:ENSG00000231752 +647123 UQCRFS1P2 HGNC:HGNC:39172 +647132 LOC647132 - +647135 SRGAP2B MIM:614703|HGNC:HGNC:35237|Ensembl:ENSG00000196369|Vega:OTTHUMG00000041442 +647144 ABHD17AP8 HGNC:HGNC:38509 +647145 LOC647145 - +647150 LOC647150 - +647155 RPS15AP20 HGNC:HGNC:36391 +647156 ACTR3BP3 HGNC:HGNC:38678 +647158 RPSAP33 HGNC:HGNC:35556 +647162 KRT18P33 HGNC:HGNC:33402 +647166 C13orf42 HGNC:HGNC:42693 +647167 EEF1A1P14 HGNC:HGNC:3197 +647169 GSTA12P HGNC:HGNC:49906 +647174 SERPINE3 HGNC:HGNC:24774|Ensembl:ENSG00000253309|Vega:OTTHUMG00000016943 +647175 GSTA11P HGNC:HGNC:49905 +647177 GSTA10P HGNC:HGNC:49904 +647187 IGHV3OR16-6 HGNC:HGNC:5641|IMGT/GENE-DB:IGHV3/OR16-6 +647190 RPS16P5 HGNC:HGNC:36183 +647195 PRR13P1 HGNC:HGNC:50614 +647201 RPL23AP16 HGNC:HGNC:36652 +647208 LOC647208 - +647211 LOC647211 - +647215 MROH3P HGNC:HGNC:33122 +647219 ASCL5 HGNC:HGNC:33169|Ensembl:ENSG00000232237|Vega:OTTHUMG00000057661 +647236 RPL39P15 HGNC:HGNC:35856 +647249 GAPDHP36 HGNC:HGNC:37790 +647253 LOC647253 - +647264 LOC647264 - +647265 CYP2AB1P HGNC:HGNC:39975 +647275 LOC647275 - +647276 RPL4P4 HGNC:HGNC:36179 +647285 RPL29P9 HGNC:HGNC:35729 +647286 RD3L HGNC:HGNC:40912|Ensembl:ENSG00000227729|Vega:OTTHUMG00000152877 +647288 CTAGE11P HGNC:HGNC:37293|Ensembl:ENSG00000214249 +647298 HSPD1P8 HGNC:HGNC:35145 +647299 LOC647299 - +647302 LSM3P3 HGNC:HGNC:44348 +647307 PEBP1P2 HGNC:HGNC:44344 +647309 GMNC MIM:614448|HGNC:HGNC:40049|Ensembl:ENSG00000205835|Vega:OTTHUMG00000156195 +647310 TEX22 HGNC:HGNC:40026|Ensembl:ENSG00000226174|Vega:OTTHUMG00000156137 +647317 GYG1P2 HGNC:HGNC:39710 +647319 VEZF1P1 HGNC:HGNC:32320 +647323 LINC02026 HGNC:HGNC:52861|Ensembl:ENSG00000214146 +647415 ALG1L5P HGNC:HGNC:44374 +647436 RPL5P1 HGNC:HGNC:10361 +647476 FRG2EP HGNC:HGNC:51365 +647481 LOC647481 - +647503 LOC647503 - +647507 CNN2P4 HGNC:HGNC:39529 +647532 FARSBP1 HGNC:HGNC:45115 +647569 PFN1P12 HGNC:HGNC:42995 +647589 ANHX HGNC:HGNC:40024|Ensembl:ENSG00000227059|Vega:OTTHUMG00000167949 +647654 CDC27P5 HGNC:HGNC:51755 +647696 CDC27P1 HGNC:HGNC:38091 +647859 LOC647859 - +647946 MIR924HG HGNC:HGNC:44332|Ensembl:ENSG00000267374 +647979 NORAD MIM:617037|HGNC:HGNC:44311|Ensembl:ENSG00000260032 +647996 LOC647996 - +648000 RPL7P23 HGNC:HGNC:35658 +648217 RPL37P23 HGNC:HGNC:37003 +648262 CICP26 HGNC:HGNC:48834 +648283 TERF1P4 HGNC:HGNC:38500 +648294 RPL23AP57 HGNC:HGNC:36971 +648315 VN2R9P HGNC:HGNC:33215 +648343 RPS29P9 HGNC:HGNC:36913 +648359 ABHD17AP3 HGNC:HGNC:34041 +648442 LOC648442 - +648532 NRBF2P1 HGNC:HGNC:44604 +648630 TSSK5P HGNC:HGNC:31931 +648691 LL22NC03-63E9.3 Ensembl:ENSG00000220891 +648729 RPS15AP24 HGNC:HGNC:36174 +648740 ACTG1P4 HGNC:HGNC:149 +648771 LOC648771 - +648774 LOC648774 - +648791 PPP1R3G HGNC:HGNC:14945|Ensembl:ENSG00000219607|Vega:OTTHUMG00000014172 +648809 EFTUD1P1 HGNC:HGNC:31739 +648822 HMGN2P18 HGNC:HGNC:39382 +648927 LOC648927 - +648934 LOC648934 - +648947 AKR1C7P HGNC:HGNC:44681 +648980 BCRP5 HGNC:HGNC:1018 +648987 LOC648987 Ensembl:ENSG00000177738 +649024 LOC649024 - +649133 LOC649133 Ensembl:ENSG00000259541 +649137 ZSCAN5C HGNC:HGNC:34294 +649166 LOC649166 - +649179 PRAMENP HGNC:HGNC:34302|Ensembl:ENSG00000197549 +649186 VN2R17P HGNC:HGNC:33223 +649238 PNMA6E HGNC:HGNC:50767 +649264 CES5AP1 HGNC:HGNC:38516 +649288 AK4P6 HGNC:HGNC:39069 +649299 RPL36AP51 HGNC:HGNC:36632 +649305 LOC649305 - +649324 PRAMEF34P HGNC:HGNC:51895 +649330 HNRNPCL3 HGNC:HGNC:51235|Ensembl:ENSG00000277058 +649352 LOC649352 - +649395 YWHAEP1 HGNC:HGNC:49442 +649446 DLGAP1-AS1 HGNC:HGNC:31676 +649458 MPTX1 HGNC:HGNC:48364 +649489 PPP1R2P5 HGNC:HGNC:16320 +649620 CDC27P6 HGNC:HGNC:51756 +649873 LOC649873 - +649925 SETP16 HGNC:HGNC:42935 +649946 RPL23AP64 HGNC:HGNC:36552 +650024 LOC650024 - +650059 RPL21P82 HGNC:HGNC:36307 +650172 CCT4P1 HGNC:HGNC:35151 +650181 LOC650181 - +650226 LOC650226 - +650236 PRAMEF32P HGNC:HGNC:51894 +650293 LOC650293 - +650368 TSSC2 MIM:608999|HGNC:HGNC:12384|Ensembl:ENSG00000223756 +650474 TPSP2 HGNC:HGNC:14136 +650560 DDX3P3 HGNC:HGNC:42173 +650623 BEND3P3 HGNC:HGNC:45016 +650655 ABCA17P HGNC:HGNC:32972|Ensembl:ENSG00000238098 +650669 GAS6-AS1 HGNC:HGNC:39826 +650747 IMPA1P1 HGNC:HGNC:33956 +650788 RPS28P9 HGNC:HGNC:36193 +650794 MIPEPP3 HGNC:HGNC:39458 +650808 RPL4P1 HGNC:HGNC:23551 +650866 LOC650866 - +650901 RPS2P12 HGNC:HGNC:36546 +650983 RCC2P1 HGNC:HGNC:37710 +651053 DDX18P2 HGNC:HGNC:21432 +651144 NACAP2 HGNC:HGNC:49489 +651249 RPL34P27 HGNC:HGNC:36369 +651250 LRRC37A16P HGNC:HGNC:43820 +651258 GAPDHP37 HGNC:HGNC:37791 +651302 ZNF192P1 HGNC:HGNC:18777|Ensembl:ENSG00000226314 +651337 LOC651337 - +651430 FLJ38576 Ensembl:ENSG00000279943 +651452 POM121L3P HGNC:HGNC:16440 +651600 RPL36P16 HGNC:HGNC:37010 +651628 EEF1GP3 HGNC:HGNC:44558 +651644 LOC651644 - +651714 MUC20P1 HGNC:HGNC:51921 +651746 ANKRD33B HGNC:HGNC:35240|Ensembl:ENSG00000164236|Vega:OTTHUMG00000162050 +651815 KLF3P1 HGNC:HGNC:41518 +652070 SCFV - +652170 COX4I1P2 HGNC:HGNC:38036 +652276 LOC652276 Ensembl:ENSG00000215154 +652411 RPSAP44 HGNC:HGNC:36891 +652423 NPM1P36 HGNC:HGNC:45215 +652489 SUMO2P3 HGNC:HGNC:39013 +652549 LOC652549 - +652608 LOC652608 - +652624 RPSAP46 HGNC:HGNC:36082 +652670 RPS3AP15 HGNC:HGNC:35781 +652873 IGKV2OR2-7 HGNC:HGNC:5810|IMGT/GENE-DB:IGKV2/OR2-7 +652904 CKS1BP6 HGNC:HGNC:24608 +652959 BTF3P5 HGNC:HGNC:38565 +652960 BTF3P7 HGNC:HGNC:38569 +652961 BTF3P8 HGNC:HGNC:38572 +652963 BTF3P12 MIM:603738|HGNC:HGNC:1127 +652964 BTF3P3 HGNC:HGNC:31100 +652965 SNORA48 HGNC:HGNC:32641|Ensembl:ENSG00000209582 +652966 SNORD10 HGNC:HGNC:32706|Ensembl:ENSG00000238917 +652968 CASTOR1 MIM:617034|HGNC:HGNC:34423|Ensembl:ENSG00000239282|Vega:OTTHUMG00000150929 +652969 SLC6A21P HGNC:HGNC:31400 +652972 LRRC37A5P HGNC:HGNC:23369|Ensembl:ENSG00000204173 +652974 RPL17P2 HGNC:HGNC:23540 +652975 RPL21P6 HGNC:HGNC:23542 +652978 RPL7AP2 HGNC:HGNC:23552 +652980 RPS28P1 HGNC:HGNC:23561 +652983 RPL35AP2 HGNC:HGNC:19914 +652985 RPL7AP4 HGNC:HGNC:23554 +652991 SKOR2 MIM:617138|HGNC:HGNC:32695|Ensembl:ENSG00000215474|Vega:OTTHUMG00000180309 +652995 UCA1 MIM:617500|HGNC:HGNC:37126|Ensembl:ENSG00000214049 +653017 TBC1D3P3 HGNC:HGNC:32408 +653042 REXO1L4P HGNC:HGNC:32241 +653045 PTPN20CP HGNC:HGNC:23424 +653061 GOLGA8S HGNC:HGNC:44409 +653067 XAGE1E MIM:300289|MIM:300744|MIM:300745|HGNC:HGNC:18372|Ensembl:ENSG00000204382|Vega:OTTHUMG00000163577 +653071 LOC653071 - +653073 GOLGA8J HGNC:HGNC:38650|Ensembl:ENSG00000179938|Vega:OTTHUMG00000175635 +653075 GOLGA8T HGNC:HGNC:44410 +653079 RPL21P98 HGNC:HGNC:36397 +653080 LOC653080 - +653082 ZDHHC11B HGNC:HGNC:32962|Ensembl:ENSG00000206077 +653108 CXADRP1 HGNC:HGNC:23770 +653113 FAM86FP HGNC:HGNC:42357 +653115 HNRNPA3P6 HGNC:HGNC:48495 +653121 ZBTB8A HGNC:HGNC:24172|Ensembl:ENSG00000160062|Vega:OTTHUMG00000007855 +653122 LSM12P1 HGNC:HGNC:32453 +653123 FAM74A6 HGNC:HGNC:34036|Ensembl:ENSG00000274516 +653125 GOLGA8K HGNC:HGNC:38652|Ensembl:ENSG00000249931|Vega:OTTHUMG00000175395 +653140 FAM228A HGNC:HGNC:34418|Ensembl:ENSG00000186453|Vega:OTTHUMG00000151903 +653145 ANXA8 MIM:602396|HGNC:HGNC:546|Ensembl:ENSG00000265190|Vega:OTTHUMG00000188209 +653147 RPL26P30 HGNC:HGNC:36733 +653149 NBPF6 MIM:613996|HGNC:HGNC:31988|Ensembl:ENSG00000186086|Vega:OTTHUMG00000039830 +653155 LOC653155 - +653156 RPL21P53 HGNC:HGNC:36574 +653160 LOC653160 Ensembl:ENSG00000241014 +653162 RPSAP9 HGNC:HGNC:31463 +653163 LCN1P2 HGNC:HGNC:23680 +653166 OR1D4 HGNC:HGNC:8185|Ensembl:ENSG00000255095|Vega:OTTHUMG00000166844 +653174 TSPY6P HGNC:HGNC:34039 +653175 HAUS6P1 HGNC:HGNC:43764 +653188 GUSBP3 HGNC:HGNC:37301|Ensembl:ENSG00000253203 +653189 BTF3L4P2 HGNC:HGNC:39646 +653190 ABCC6P1 HGNC:HGNC:33352|Ensembl:ENSG00000256340 +653192 TRIM43B HGNC:HGNC:37146|Ensembl:ENSG00000144010 +653194 KHDC1P1 HGNC:HGNC:43757 +653199 TCAF1P1 HGNC:HGNC:33604 +653203 FAM230A HGNC:HGNC:45045|Ensembl:ENSG00000277870 +653214 PPIAP22 HGNC:HGNC:17236 +653220 XAGE1B MIM:300742|MIM:300743|HGNC:HGNC:25400|Ensembl:ENSG00000204379|Vega:OTTHUMG00000163577 +653226 SRP9P1 HGNC:HGNC:23402 +653232 RPL15P3 HGNC:HGNC:21538 +653234 AGAP10P HGNC:HGNC:23659 +653236 RPL23AP49 HGNC:HGNC:35689 +653238 GTF2H2B HGNC:HGNC:31393 +653240 KRTAP4-11 HGNC:HGNC:18911|Ensembl:ENSG00000212721|Vega:OTTHUMG00000133586 +653247 PRB2 MIM:168810|HGNC:HGNC:9338|Ensembl:ENSG00000121335|Vega:OTTHUMG00000156975 +653259 AGAP14 HGNC:HGNC:23660 +653268 AGAP7P HGNC:HGNC:23465 +653269 POTEI HGNC:HGNC:37093|Ensembl:ENSG00000196834|Vega:OTTHUMG00000153925 +653275 CFC1B HGNC:HGNC:33983|Ensembl:ENSG00000152093|Vega:OTTHUMG00000153959 +653282 CT47A7 MIM:300786|HGNC:HGNC:33288|Ensembl:ENSG00000228517|Vega:OTTHUMG00000022317 +653288 TSPY7P HGNC:HGNC:34040 +653303 LOC653303 - +653308 ASAH2B HGNC:HGNC:23456|Ensembl:ENSG00000204147|Vega:OTTHUMG00000018239 +653314 RPL19P9 HGNC:HGNC:35918 +653316 FAM153C HGNC:HGNC:33936|Ensembl:ENSG00000204677|Vega:OTTHUMG00000163459 +653319 KIAA0895L HGNC:HGNC:34408|Ensembl:ENSG00000196123|Vega:OTTHUMG00000172891 +653333 FAM86B2 MIM:616123|HGNC:HGNC:32222|Ensembl:ENSG00000145002|Vega:OTTHUMG00000165462 +653354 ARMCX7P HGNC:HGNC:49917 +653361 NCF1 MIM:608512|HGNC:HGNC:7660|Ensembl:ENSG00000158517|Vega:OTTHUMG00000149965 +653363 TEX28P2 HGNC:HGNC:33357 +653364 HSPB1P2 HGNC:HGNC:5252 +653381 SORD2P HGNC:HGNC:49919 +653390 RRN3P2 HGNC:HGNC:37619|Ensembl:ENSG00000103472 +653399 GSTTP2 HGNC:HGNC:33606 +653404 FOXD4L6 HGNC:HGNC:31986|Ensembl:ENSG00000273514|Vega:OTTHUMG00000188618 +653406 LOC653406 - +653423 SPAG11A HGNC:HGNC:33342|Ensembl:ENSG00000178287|Vega:OTTHUMG00000162440 +653427 FOXD4L5 HGNC:HGNC:18522|Ensembl:ENSG00000204779|Vega:OTTHUMG00000013332 +653435 GUSBP6 HGNC:HGNC:42320 +653436 ANKRD20A7P HGNC:HGNC:31980 +653437 AQP12B HGNC:HGNC:6096|Ensembl:ENSG00000185176|Vega:OTTHUMG00000152263 +653440 WASH6P HGNC:HGNC:31685 +653441 PHC1P1 HGNC:HGNC:34502 +653447 HNRNPCP2 HGNC:HGNC:48814 +653453 FGF7P5 HGNC:HGNC:33588 +653458 BMS1P9 HGNC:HGNC:49155 +653464 SRGAP2C MIM:614704|HGNC:HGNC:30584|Ensembl:ENSG00000171943|Vega:OTTHUMG00000041445 +653479 MRPL45P2 HGNC:HGNC:29716 +653483 AFDN-AS1 HGNC:HGNC:21236|Ensembl:ENSG00000198221 +653486 SCGB1C2 HGNC:HGNC:51242|Ensembl:ENSG00000268320|Vega:OTTHUMG00000189257 +653489 RGPD3 MIM:612706|HGNC:HGNC:32416|Ensembl:ENSG00000153165|Vega:OTTHUMG00000153182 +653492 PSG10P MIM:176399|HGNC:HGNC:9515 +653499 LGALS7B MIM:617139|HGNC:HGNC:34447|Ensembl:ENSG00000178934|Vega:OTTHUMG00000182607 +653503 LOC653503 - +653505 PPIAL4A HGNC:HGNC:24369|Ensembl:ENSG00000263353|Vega:OTTHUMG00000185015 +653509 SFTPA1 MIM:178630|HGNC:HGNC:10798|Ensembl:ENSG00000122852|Vega:OTTHUMG00000018565 +653510 CBWD4P HGNC:HGNC:18520 +653513 LOC653513 - +653519 GPR89A MIM:612821|HGNC:HGNC:31984|Ensembl:ENSG00000117262|Vega:OTTHUMG00000013738 +653543 DUX4L7 HGNC:HGNC:37266 +653544 DUX4L6 HGNC:HGNC:37265 +653545 DUX4L5 HGNC:HGNC:38689 +653548 DUX4L3 HGNC:HGNC:38688 +653550 TP53TG3C HGNC:HGNC:42962|Ensembl:ENSG00000205457|Vega:OTTHUMG00000176458 +653553 HSPB1P1 HGNC:HGNC:5251 +653557 BMS1P8 HGNC:HGNC:49152 +653562 SLC6A10PB - +653566 SPCS2P4 HGNC:HGNC:45237 +653567 TMEM236 HGNC:HGNC:23473|Ensembl:ENSG00000148483|Vega:OTTHUMG00000017753 +653579 CD177P1 HGNC:HGNC:34508 +653583 PHLDB3 HGNC:HGNC:30499|Ensembl:ENSG00000176531|Vega:OTTHUMG00000150693 +653588 LOC653588 - +653590 GGTLC5P HGNC:HGNC:33427 +653598 PPIAL4C HGNC:HGNC:33995|Ensembl:ENSG00000263464|Vega:OTTHUMG00000188675 +653604 HIST2H3D HGNC:HGNC:25311|Ensembl:ENSG00000183598|Vega:OTTHUMG00000012092 +653606 PRAMEF22 HGNC:HGNC:34393 +653619 PRAMEF15 HGNC:HGNC:26764|Ensembl:ENSG00000204501|Vega:OTTHUMG00000008035 +653631 LOC653631 - +653635 WASH7P HGNC:HGNC:38034 +653639 LYPLA2P1 HGNC:HGNC:21069 +653641 GOLGA6C HGNC:HGNC:32206|Ensembl:ENSG00000167195|Vega:OTTHUMG00000172671 +653643 GOLGA6D HGNC:HGNC:32204|Ensembl:ENSG00000140478|Vega:OTTHUMG00000172672 +653645 TBC1D3P1-DHX40P1 HGNC:HGNC:42362|Ensembl:ENSG00000267104 +653650 PDPK2P HGNC:HGNC:49897 +653653 LOC653653 Ensembl:ENSG00000280852 +653656 MBD3L4 HGNC:HGNC:37206|Ensembl:ENSG00000205718|Vega:OTTHUMG00000181974 +653657 MBD3L3 HGNC:HGNC:37205|Ensembl:ENSG00000182315|Vega:OTTHUMG00000181976 +653658 RPS23P8 HGNC:HGNC:35982 +653659 TMEM183B MIM:611365|HGNC:HGNC:33205 +653665 RPL21P93 HGNC:HGNC:35646 +653677 SEC1P HGNC:HGNC:44149|Ensembl:ENSG00000232871 +653687 FAM226B HGNC:HGNC:31964 +653689 GSTT2B HGNC:HGNC:33437|Ensembl:ENSG00000133433|Vega:OTTHUMG00000150774 +653691 TCAF2P1 HGNC:HGNC:33603 +653698 LOC653698 - +653702 RPL7P9 HGNC:HGNC:37028 +653707 PDCL2P1 HGNC:HGNC:50340 +653712 LOC653712 Ensembl:ENSG00000231305 +653720 GOLGA8M HGNC:HGNC:44404|Ensembl:ENSG00000188626|Vega:OTTHUMG00000176338 +653737 RPL21P119 HGNC:HGNC:35614 +653753 VN1R6P HGNC:HGNC:13712 +653758 TPM3P6 HGNC:HGNC:39169 +653773 RPL31P17 HGNC:HGNC:36995 +653781 POTEJ HGNC:HGNC:37094|Ensembl:ENSG00000222038|Vega:OTTHUMG00000154050 +653784 MZT2A MIM:613449|HGNC:HGNC:33187|Ensembl:ENSG00000173272|Vega:OTTHUMG00000153606 +653786 LOC653786 Ensembl:ENSG00000257838 +653789 RPL23AP25 HGNC:HGNC:35672 +653794 TRIM60P14 HGNC:HGNC:38486 +653805 RPS27P8 HGNC:HGNC:36022 +653808 ZG16 MIM:617311|HGNC:HGNC:30961|Ensembl:ENSG00000174992|Vega:OTTHUMG00000177139 +653820 FAM72B MIM:614711|HGNC:HGNC:24805|Ensembl:ENSG00000188610|Vega:OTTHUMG00000185025 +653857 ACTR3C HGNC:HGNC:37282|Ensembl:ENSG00000106526|Vega:OTTHUMG00000158323 +653895 PGGT1BP1 HGNC:HGNC:45024 +653924 GPAT2P2 HGNC:HGNC:52331 +654029 RPS10P15 HGNC:HGNC:35860 +654170 RPS16P8 HGNC:HGNC:35608 +654231 OCM MIM:164795|HGNC:HGNC:8105|Ensembl:ENSG00000122543|Vega:OTTHUMG00000155499 +654254 ZNF732 HGNC:HGNC:37138|Ensembl:ENSG00000186777|Vega:OTTHUMG00000159883 +654319 SNORA5A HGNC:HGNC:32588|Ensembl:ENSG00000206838 +654320 SNORA8 HGNC:HGNC:32596|Ensembl:ENSG00000207304 +654321 SNORA75 HGNC:HGNC:32661|Ensembl:ENSG00000206885 +654322 SNORA13 HGNC:HGNC:32601|Ensembl:ENSG00000238363 +654337 BCYRN1P3 HGNC:HGNC:39833 +654338 LOC654338 - +654340 RNPC3P1 HGNC:HGNC:47036 +654342 LOC654342 - +654346 LGALS9C HGNC:HGNC:33874|Ensembl:ENSG00000171916|Vega:OTTHUMG00000059251 +654350 RPL9P25 HGNC:HGNC:36112 +654364 NME1-NME2 HGNC:HGNC:33531|Ensembl:ENSG00000011052|Vega:OTTHUMG00000137475 +654365 RPS27P3 HGNC:HGNC:17445 +654369 RPL37P5 HGNC:HGNC:23549 +654370 RPL7AP3 HGNC:HGNC:23553 +654371 RPS15AP4 HGNC:HGNC:23559 +654376 RPL12P9 HGNC:HGNC:23766 +654377 CHES1L1 HGNC:HGNC:23778 +654381 RPL7P5 HGNC:HGNC:28886 +654382 RPL19P2 HGNC:HGNC:29946 +654383 RPL13P4 HGNC:HGNC:31027 +654385 RPL21P15 HGNC:HGNC:31030 +654386 RPL26P5 HGNC:HGNC:31031 +654387 RPL31P6 HGNC:HGNC:31032 +654388 RPL32P2 HGNC:HGNC:31033 +654390 RPS27P2 HGNC:HGNC:31035 +654391 RPL31P7 HGNC:HGNC:31325 +654392 RPL39P4 HGNC:HGNC:31327 +654412 FAM138B HGNC:HGNC:33582|Ensembl:ENSG00000226516 +654427 PCNPP1 HGNC:HGNC:32440 +654429 LRTM2 HGNC:HGNC:32443|Ensembl:ENSG00000166159|Vega:OTTHUMG00000168088 +654433 PAX8-AS1 HGNC:HGNC:49271|Ensembl:ENSG00000189223 +654434 SNHG20 HGNC:HGNC:33099|Ensembl:ENSG00000234912 +654463 FER1L6 HGNC:HGNC:28065|Ensembl:ENSG00000214814|Vega:OTTHUMG00000164998 +654466 FGF7P3 HGNC:HGNC:26671 +654480 ATP5G2P4 HGNC:HGNC:42188 +654483 BOLA2B HGNC:HGNC:32479|Ensembl:ENSG00000169627|Vega:OTTHUMG00000176858 +654484 ATP5J2P5 HGNC:HGNC:33611 +654485 ATP5J2P4 HGNC:HGNC:32451 +654486 ATP5J2P6 HGNC:HGNC:33612 +654499 FAM30C HGNC:HGNC:31024 +654500 H2AFVP1 HGNC:HGNC:31026 +654502 IQCJ MIM:611622|HGNC:HGNC:32406|Ensembl:ENSG00000214216|Vega:OTTHUMG00000166440 +654503 HMGB1P9 HGNC:HGNC:13320 +654505 H3F3AP1 HGNC:HGNC:31028 +654506 RPSAP7 HGNC:HGNC:31461 +654780 LOC654780 - +654783 IFNNP1 HGNC:HGNC:32009 +654790 PCP4L1 HGNC:HGNC:20448|Ensembl:ENSG00000248485|Vega:OTTHUMG00000034340 +654813 P2RY10P1 HGNC:HGNC:19063 +654816 NCF1B HGNC:HGNC:32522|Ensembl:ENSG00000182487 +654817 NCF1C HGNC:HGNC:32523|Ensembl:ENSG00000165178 +654835 FAM138C HGNC:HGNC:32333|Ensembl:ENSG00000218839 +654841 LOC654841 Ensembl:ENSG00000236432 +664611 H3F3AP2 HGNC:HGNC:19823 +664612 MIR539 HGNC:HGNC:32529|Ensembl:ENSG00000202560|miRBase:MI0003514 +664613 MIR544A HGNC:HGNC:32530|Ensembl:ENSG00000207587|miRBase:MI0003515 +664614 MIR545 HGNC:HGNC:32531|Ensembl:ENSG00000207820|miRBase:MI0003516 +664615 MIR376A2 MIM:610960|HGNC:HGNC:32532|Ensembl:ENSG00000283561|miRBase:MI0003529 +664616 MIR487B MIM:615037|HGNC:HGNC:32533|Ensembl:ENSG00000207754|miRBase:MI0003530 +664617 MIR542 HGNC:HGNC:32534|Ensembl:ENSG00000207784|miRBase:MI0003686 +664618 HSP90AB4P HGNC:HGNC:32538 +664701 ZNF826P HGNC:HGNC:33875 +664709 HNRNPA1P10 HGNC:HGNC:39128 +664721 HNRNPA1P27 HGNC:HGNC:39545 +664722 HNRNPA1P26 HGNC:HGNC:39544 +664728 CMD1Q MIM:609915|HGNC:HGNC:32552 +664780 MYP12 MIM:609995|HGNC:HGNC:32551 +677662 PARK12 MIM:300557|HGNC:HGNC:34510 +677663 PAND3 MIM:609985 +677679 SCARNA3 HGNC:HGNC:32577|Ensembl:ENSG00000252906 +677681 SCARNA20 HGNC:HGNC:32578|Ensembl:ENSG00000252577 +677762 LOC677762 - +677763 SCARNA21 HGNC:HGNC:32579|Ensembl:ENSG00000252835 +677764 MYP13 MIM:300613|HGNC:HGNC:32582 +677765 SCARNA18 MIM:611329|HGNC:HGNC:32559|Ensembl:ENSG00000238835 +677766 SCARNA2 HGNC:HGNC:32558|Ensembl:ENSG00000270066|Ensembl:ENSG00000278249 +677767 SCARNA7 MIM:615644|HGNC:HGNC:32563|Ensembl:ENSG00000238741 +677768 SCARNA13 HGNC:HGNC:32570|Ensembl:ENSG00000252481 +677769 SCARNA17 MIM:615645|HGNC:HGNC:32574|Ensembl:ENSG00000267322 +677770 SCARNA22 HGNC:HGNC:32580|Ensembl:ENSG00000249784 +677771 SCARNA4 HGNC:HGNC:32560|Ensembl:ENSG00000280466|Ensembl:ENSG00000281394 +677772 SCARNA6 MIM:615641|HGNC:HGNC:32562|Ensembl:ENSG00000251791 +677773 SCARNA23 HGNC:HGNC:32581|Ensembl:ENSG00000251869 +677774 SCARNA1 HGNC:HGNC:32555|Ensembl:ENSG00000252947 +677775 SCARNA5 MIM:615640|HGNC:HGNC:32561|Ensembl:ENSG00000252010 +677776 SCARNA8 MIM:615646|HGNC:HGNC:32564|Ensembl:ENSG00000251733 +677777 SCARNA12 MIM:615642|HGNC:HGNC:32569|Ensembl:ENSG00000238795 +677778 SCARNA15 MIM:612675|HGNC:HGNC:32572|Ensembl:ENSG00000277864 +677779 LINC00488 HGNC:HGNC:32675|Ensembl:ENSG00000214381 +677780 SCARNA11 HGNC:HGNC:32568|Ensembl:ENSG00000251898 +677781 SCARNA16 HGNC:HGNC:32573|Ensembl:ENSG00000275143 +677784 FAM138D HGNC:HGNC:33583|Ensembl:ENSG00000249054 +677790 TMEM78 HGNC:HGNC:32307 +677792 SNORA1 HGNC:HGNC:32557|Ensembl:ENSG00000206834 +677793 SNORA2A HGNC:HGNC:32584|Ensembl:ENSG00000206612 +677794 SNORA2B HGNC:HGNC:32585|Ensembl:ENSG00000207313 +677795 SNORA5B HGNC:HGNC:32589|Ensembl:ENSG00000200656 +677796 SNORA5C MIM:611335|HGNC:HGNC:32590|Ensembl:ENSG00000201772 +677797 SNORA7B HGNC:HGNC:32593|Ensembl:ENSG00000207088 +677798 SNORA9 HGNC:HGNC:32597|Ensembl:ENSG00000277184 +677799 SNORA11 MIM:300662|HGNC:HGNC:32599|Ensembl:ENSG00000221716 +677800 SNORA12 MIM:611330|HGNC:HGNC:32600|Ensembl:ENSG00000212464 +677801 SNORA14A HGNC:HGNC:32602|Ensembl:ENSG00000201643 +677802 SNORA14B HGNC:HGNC:32603|Ensembl:ENSG00000207181 +677803 SNORA15 HGNC:HGNC:32604|Ensembl:ENSG00000207168 +677804 SNORA17A HGNC:HGNC:32607|Ensembl:ENSG00000274998|Ensembl:ENSG00000281808 +677805 SNORA18 HGNC:HGNC:32608|Ensembl:ENSG00000207145 +677806 SNORA20 HGNC:HGNC:32610|Ensembl:ENSG00000207392 +677807 SNORA22 HGNC:HGNC:32612|Ensembl:ENSG00000206634 +677808 SNORA23 HGNC:HGNC:32613|Ensembl:ENSG00000201998 +677809 SNORA24 HGNC:HGNC:32614|Ensembl:ENSG00000275994 +677810 SNORA26 MIM:614626|HGNC:HGNC:32616|Ensembl:ENSG00000212588 +677811 SNORA28 HGNC:HGNC:32618|Ensembl:ENSG00000272533 +677812 SNORA29 HGNC:HGNC:32619|Ensembl:ENSG00000206910 +677813 SNORA30 HGNC:HGNC:32620|Ensembl:ENSG00000206755 +677814 SNORA31 HGNC:HGNC:32621|Ensembl:ENSG00000199477 +677815 SNORA2C MIM:615487|HGNC:HGNC:32624|Ensembl:ENSG00000221491 +677816 SNORA35 HGNC:HGNC:32625|Ensembl:ENSG00000208839 +677817 SNORA36A HGNC:HGNC:32628|Ensembl:ENSG00000206948 +677818 SNORA36B HGNC:HGNC:32629|Ensembl:ENSG00000222370 +677819 SNORA37 HGNC:HGNC:32630|Ensembl:ENSG00000207233 +677820 SNORA38 HGNC:HGNC:32631|Ensembl:ENSG00000200816 +677821 SNORA71E HGNC:HGNC:32632|Ensembl:ENSG00000274309 +677822 SNORA40 HGNC:HGNC:32633|Ensembl:ENSG00000210825 +677823 SNORA80E HGNC:HGNC:32635|Ensembl:ENSG00000207475 +677824 SNORA17B HGNC:HGNC:32636|Ensembl:ENSG00000276161|Ensembl:ENSG00000280496 +677825 SNORA44 HGNC:HGNC:32637|Ensembl:ENSG00000273544 +677826 SNORA3B MIM:611333|HGNC:HGNC:32638|Ensembl:ENSG00000212607 +677827 SNORA46 HGNC:HGNC:32639|Ensembl:ENSG00000207493 +677828 SNORA47 HGNC:HGNC:32640|Ensembl:ENSG00000238961 +677829 SNORA49 HGNC:HGNC:32642|Ensembl:ENSG00000208892 +677830 SNORA50A HGNC:HGNC:32643|Ensembl:ENSG00000206952|Ensembl:ENSG00000281910 +677831 SNORA51 HGNC:HGNC:32644|Ensembl:ENSG00000271798 +677832 SNORA53 HGNC:HGNC:32646|Ensembl:ENSG00000212443 +677833 SNORA54 HGNC:HGNC:32647|Ensembl:ENSG00000207008 +677834 SNORA55 HGNC:HGNC:32649|Ensembl:ENSG00000201457 +677835 SNORA56 HGNC:HGNC:32650|Ensembl:ENSG00000206693 +677836 SNORA58 HGNC:HGNC:32652 +677837 SNORA60 HGNC:HGNC:32654|Ensembl:ENSG00000199266 +677838 SNORA61 HGNC:HGNC:32655|Ensembl:ENSG00000278274 +677839 SNORA71C HGNC:HGNC:32656|Ensembl:ENSG00000201512 +677840 SNORA71D HGNC:HGNC:32657|Ensembl:ENSG00000200354 +677841 SNORA74B MIM:611331|HGNC:HGNC:32660|Ensembl:ENSG00000212402 +677842 SNORA50C HGNC:HGNC:32662|Ensembl:ENSG00000277887|Ensembl:ENSG00000281311 +677843 SNORA77 HGNC:HGNC:32663|Ensembl:ENSG00000221643 +677844 SNORA78 HGNC:HGNC:32664|Ensembl:ENSG00000273587 +677845 SNORA79 HGNC:HGNC:32665|Ensembl:ENSG00000221303 +677846 SNORA80A HGNC:HGNC:32666|Ensembl:ENSG00000200792 +677847 SNORA81 MIM:611334|HGNC:HGNC:32667|Ensembl:ENSG00000221420 +677848 SNORD1A HGNC:HGNC:32556|Ensembl:ENSG00000278261 +677849 SNORD1B HGNC:HGNC:32676|Ensembl:ENSG00000199961 +677850 SNORD1C HGNC:HGNC:32677|Ensembl:ENSG00000274091 +677880 THEM4P1 HGNC:HGNC:32692 +677882 SNORA59B HGNC:HGNC:32658|Ensembl:ENSG00000266079 +677883 CHTF8P1 HGNC:HGNC:35443 +677885 SNORA59A HGNC:HGNC:32653|Ensembl:ENSG00000239149 +678655 CD27-AS1 HGNC:HGNC:43896|Ensembl:ENSG00000215039 +678656 ZRF1PS - +684959 SNORA25 HGNC:HGNC:32615|Ensembl:ENSG00000207112 +692053 SNORD9 HGNC:HGNC:32705|Ensembl:ENSG00000199436 +692057 SNORD12 HGNC:HGNC:32708|Ensembl:ENSG00000212304 +692058 SNORD11 HGNC:HGNC:32707|Ensembl:ENSG00000238317 +692063 SNORA32 HGNC:HGNC:32622|Ensembl:ENSG00000206799 +692072 SNORD5 HGNC:HGNC:32702|Ensembl:ENSG00000239195 +692073 SNORA16A HGNC:HGNC:32605|Ensembl:ENSG00000274582|Ensembl:ENSG00000280498 +692075 SNORD6 HGNC:HGNC:32703|Ensembl:ENSG00000202314 +692076 SNORD7 HGNC:HGNC:32704|Ensembl:ENSG00000207297 +692084 SNORD13 MIM:616664|HGNC:HGNC:32711|Ensembl:ENSG00000239039 +692085 SNORD45C HGNC:HGNC:32720|Ensembl:ENSG00000206620 +692086 SNORD17 HGNC:HGNC:32713|Ensembl:ENSG00000212232 +692087 SNORD49B HGNC:HGNC:32721 +692088 SNORD50B MIM:613264|HGNC:HGNC:32722|Ensembl:ENSG00000275072 +692089 SNORD19 HGNC:HGNC:32717|Ensembl:ENSG00000212493 +692090 SNORD59B HGNC:HGNC:32723 +692091 SNORD23 HGNC:HGNC:32718|Ensembl:ENSG00000221803 +692092 SNORD32B HGNC:HGNC:32719|Ensembl:ENSG00000201330 +692093 SNORD62B HGNC:HGNC:23031|Ensembl:ENSG00000231587 +692094 MSMP MIM:612191|HGNC:HGNC:29663|Ensembl:ENSG00000215183|Vega:OTTHUMG00000019882 +692099 FAM86DP HGNC:HGNC:32659|Ensembl:ENSG00000244026 +692106 SNORD65 HGNC:HGNC:32726|Ensembl:ENSG00000277512 +692107 SNORD66 HGNC:HGNC:32727|Ensembl:ENSG00000212158 +692108 SNORD67 HGNC:HGNC:32728|Ensembl:ENSG00000212135 +692109 SNORD69 HGNC:HGNC:32730|Ensembl:ENSG00000212452 +692110 SNORD70 HGNC:HGNC:32731|Ensembl:ENSG00000212534 +692111 SNORD71 HGNC:HGNC:32732|Ensembl:ENSG00000223224 +692146 RPS26P4 HGNC:HGNC:23775 +692147 HMGB1P8 HGNC:HGNC:13319 +692148 SCARNA10 MIM:615639|HGNC:HGNC:32567|Ensembl:ENSG00000239002 +692149 SCARNA14 HGNC:HGNC:32571|Ensembl:ENSG00000252712 +692157 SNORA16B HGNC:HGNC:32606|Ensembl:ENSG00000201544 +692158 SNORA57 HGNC:HGNC:32651|Ensembl:ENSG00000206597 +692159 GRASPOS HGNC:HGNC:32680 +692195 SNORD75 HGNC:HGNC:32735 +692196 SNORD76 HGNC:HGNC:32736 +692197 SNORD77 HGNC:HGNC:32737 +692198 SNORD78 HGNC:HGNC:32738 +692199 SNORD84 HGNC:HGNC:32743|Ensembl:ENSG00000265236 +692200 SNORD103C HGNC:HGNC:32744 +692201 SNORD86 HGNC:HGNC:32745|Ensembl:ENSG00000212498 +692202 SNORD88A HGNC:HGNC:32747|Ensembl:ENSG00000221241 +692203 SNORD88B HGNC:HGNC:32748|Ensembl:ENSG00000221381 +692204 SNORD88C HGNC:HGNC:32749|Ensembl:ENSG00000220988 +692205 SNORD89 HGNC:HGNC:32750|Ensembl:ENSG00000212283 +692206 SNORD90 HGNC:HGNC:32751|Ensembl:ENSG00000212447 +692207 SNORD91A HGNC:HGNC:32752|Ensembl:ENSG00000212163 +692208 SNORD91B HGNC:HGNC:32753|Ensembl:ENSG00000275084 +692209 SNORD92 HGNC:HGNC:32754|Ensembl:ENSG00000264994 +692210 SNORD93 HGNC:HGNC:32755|Ensembl:ENSG00000221740 +692211 SNORD98 HGNC:HGNC:32761|Ensembl:ENSG00000283551 +692212 SNORD99 HGNC:HGNC:32762|Ensembl:ENSG00000221539 +692213 SNORD110 HGNC:HGNC:32775|Ensembl:ENSG00000221116 +692214 SNORD111 HGNC:HGNC:32776|Ensembl:ENSG00000221066 +692215 SNORD112 MIM:613649|HGNC:HGNC:32777|Ensembl:ENSG00000275662 +692217 SNORD114@ HGNC:HGNC:32779 +692218 SNORD115@ HGNC:HGNC:32780 +692219 DFNB65 MIM:610248|HGNC:HGNC:28113 +692220 DFNB62 MIM:610143|HGNC:HGNC:29439 +692222 OPA5 MIM:610708|HGNC:HGNC:32787 +692223 SNORD97 HGNC:HGNC:32760|Ensembl:ENSG00000238622 +692224 FBXO22-AS1 HGNC:HGNC:31025 +692225 SNORD94 HGNC:HGNC:32756|Ensembl:ENSG00000208772 +692226 SNORD96B HGNC:HGNC:32759|Ensembl:ENSG00000208883 +692227 SNORD104 HGNC:HGNC:32768|Ensembl:ENSG00000199753 +692229 SNORD105 HGNC:HGNC:32769|Ensembl:ENSG00000209645 +692231 RHEBP3 HGNC:HGNC:44992 +692232 SNORD3@ HGNC:HGNC:32739 +692233 SNORD117 HGNC:HGNC:32742|Ensembl:ENSG00000201785 +692234 SNORD103A HGNC:HGNC:32766 +692235 SNORD103B HGNC:HGNC:32767 +692236 SNORD116@ HGNC:HGNC:32781 +692246 LOC692246 - +692247 LOC692247 - +692312 PPAN-P2RY11 HGNC:HGNC:33526|Ensembl:ENSG00000243207|Vega:OTTHUMG00000150165 +693120 MIR33B MIM:613486|HGNC:HGNC:32791|Ensembl:ENSG00000207839|miRBase:MI0003646 +693121 MIR411 HGNC:HGNC:32792|Ensembl:ENSG00000199109|miRBase:MI0003675 +693122 MIR421 HGNC:HGNC:32793|Ensembl:ENSG00000202566|miRBase:MI0003685 +693123 MIR449B MIM:613132|HGNC:HGNC:32794|Ensembl:ENSG00000207728|miRBase:MI0003673 +693124 MIR532 HGNC:HGNC:32795|Ensembl:ENSG00000207758|miRBase:MI0003205 +693125 MIR548A1 HGNC:HGNC:32796|Ensembl:ENSG00000207775|miRBase:MI0003593 +693126 MIR548A2 HGNC:HGNC:32797|Ensembl:ENSG00000207689|miRBase:MI0003598 +693127 MIR548A3 HGNC:HGNC:32798|Ensembl:ENSG00000208032|miRBase:MI0003612 +693128 MIR548B HGNC:HGNC:32799|Ensembl:ENSG00000207982|miRBase:MI0003596 +693129 MIR548C HGNC:HGNC:32800|Ensembl:ENSG00000207546|miRBase:MI0003630 +693130 MIR548D1 HGNC:HGNC:32801|Ensembl:ENSG00000283172|miRBase:MI0003668 +693131 MIR548D2 HGNC:HGNC:32802|Ensembl:ENSG00000263690|miRBase:MI0003671 +693132 MIR549A HGNC:HGNC:32803|Ensembl:ENSG00000208003|miRBase:MI0003679 +693133 MIR550A1 HGNC:HGNC:32804|Ensembl:ENSG00000207771|miRBase:MI0003600 +693134 MIR550A2 HGNC:HGNC:32805|Ensembl:ENSG00000207573|miRBase:MI0003601 +693135 MIR551A MIM:615148|HGNC:HGNC:32806|Ensembl:ENSG00000207776|miRBase:MI0003556 +693136 MIR551B HGNC:HGNC:32807|Ensembl:ENSG00000207717|miRBase:MI0003575 +693137 MIR552 HGNC:HGNC:32808|Ensembl:ENSG00000207941|miRBase:MI0003557 +693138 MIR553 HGNC:HGNC:32809|Ensembl:ENSG00000207750|miRBase:MI0003558 +693139 MIR554 HGNC:HGNC:32810|Ensembl:ENSG00000207606|miRBase:MI0003559 +693140 MIR555 HGNC:HGNC:32811|Ensembl:ENSG00000283701|miRBase:MI0003561 +693141 MIR556 HGNC:HGNC:32812|Ensembl:ENSG00000207729|miRBase:MI0003562 +693142 MIR557 HGNC:HGNC:32813|Ensembl:ENSG00000207974|miRBase:MI0003563 +693143 MIR558 MIM:616473|HGNC:HGNC:32814|Ensembl:ENSG00000207653|miRBase:MI0003564 +693144 MIR559 HGNC:HGNC:32815|Ensembl:ENSG00000207923|miRBase:MI0003565 +693146 MIR561 HGNC:HGNC:32817|Ensembl:ENSG00000207951|miRBase:MI0003567 +693147 MIR562 HGNC:HGNC:32818|Ensembl:ENSG00000207626|miRBase:MI0003568 +693148 MIR563 HGNC:HGNC:32819|Ensembl:ENSG00000207815|miRBase:MI0003569 +693149 MIR564 HGNC:HGNC:32820|Ensembl:ENSG00000284498|miRBase:MI0003570 +693151 MIR566 HGNC:HGNC:32822|Ensembl:ENSG00000207922|miRBase:MI0003572 +693152 MIR567 HGNC:HGNC:32823|Ensembl:ENSG00000207940|miRBase:MI0003573 +693153 MIR568 HGNC:HGNC:32824|Ensembl:ENSG00000284134|miRBase:MI0003574 +693154 MIR569 HGNC:HGNC:32825|Ensembl:ENSG00000207963|miRBase:MI0003576 +693155 MIR570 MIM:614538|HGNC:HGNC:32826|Ensembl:ENSG00000207650|miRBase:MI0003577 +693156 MIR571 HGNC:HGNC:32827|Ensembl:ENSG00000207642|miRBase:MI0003578 +693157 MIR572 HGNC:HGNC:32828|Ensembl:ENSG00000207716|miRBase:MI0003579 +693158 MIR573 HGNC:HGNC:32829|Ensembl:ENSG00000207697|miRBase:MI0003580 +693159 MIR574 MIM:615469|HGNC:HGNC:32830|Ensembl:ENSG00000207944|miRBase:MI0003581 +693160 MIR575 HGNC:HGNC:32831|Ensembl:ENSG00000207746|miRBase:MI0003582 +693161 MIR576 HGNC:HGNC:32832|Ensembl:ENSG00000207988|miRBase:MI0003583 +693162 MIR577 HGNC:HGNC:32833|Ensembl:ENSG00000207931|miRBase:MI0003584 +693163 MIR578 HGNC:HGNC:32834|Ensembl:ENSG00000207559|miRBase:MI0003585 +693164 MIR579 HGNC:HGNC:32835|Ensembl:ENSG00000207956|miRBase:MI0003586 +693165 MIR580 HGNC:HGNC:32836|Ensembl:ENSG00000207756|miRBase:MI0003587 +693166 MIR581 HGNC:HGNC:32837|Ensembl:ENSG00000207627|miRBase:MI0003588 +693167 MIR582 HGNC:HGNC:32838|Ensembl:ENSG00000202601|miRBase:MI0003589 +693168 MIR583 HGNC:HGNC:32839|Ensembl:ENSG00000207578|miRBase:MI0003590 +693169 MIR584 HGNC:HGNC:32840|Ensembl:ENSG00000207714|miRBase:MI0003591 +693170 MIR585 HGNC:HGNC:32841|Ensembl:ENSG00000207619|miRBase:MI0003592 +693171 MIR586 HGNC:HGNC:32842|Ensembl:ENSG00000207769|miRBase:MI0003594 +693172 MIR587 HGNC:HGNC:32843|Ensembl:ENSG00000207577|miRBase:MI0003595 +693173 MIR588 HGNC:HGNC:32844|Ensembl:ENSG00000207632|miRBase:MI0003597 +693174 MIR589 HGNC:HGNC:32845|Ensembl:ENSG00000207973|miRBase:MI0003599 +693175 MIR590 MIM:615070|HGNC:HGNC:32846|Ensembl:ENSG00000207741|miRBase:MI0003602 +693176 MIR591 HGNC:HGNC:32847|Ensembl:ENSG00000208025|miRBase:MI0003603 +693177 MIR592 HGNC:HGNC:32848|Ensembl:ENSG00000207692|miRBase:MI0003604 +693178 MIR593 HGNC:HGNC:32849|Ensembl:ENSG00000207588|miRBase:MI0003605 +693180 MIR595 HGNC:HGNC:32851|Ensembl:ENSG00000207637|miRBase:MI0003607 +693181 MIR596 HGNC:HGNC:32852|Ensembl:ENSG00000207826|miRBase:MI0003608 +693182 MIR597 HGNC:HGNC:32853|Ensembl:ENSG00000207701|miRBase:MI0003609 +693183 MIR598 HGNC:HGNC:32854|Ensembl:ENSG00000207600|miRBase:MI0003610 +693184 MIR599 HGNC:HGNC:32855|Ensembl:ENSG00000207804|miRBase:MI0003611 +693185 MIR600 HGNC:HGNC:32856|Ensembl:ENSG00000283941|miRBase:MI0003613 +693186 MIR601 HGNC:HGNC:32857|Ensembl:ENSG00000207991|miRBase:MI0003614 +693187 MIR602 HGNC:HGNC:32858|Ensembl:ENSG00000207693|miRBase:MI0003615 +693188 MIR603 HGNC:HGNC:32859|Ensembl:ENSG00000207930|miRBase:MI0003616 +693189 MIR604 HGNC:HGNC:32860|Ensembl:ENSG00000207612|miRBase:MI0003617 +693190 MIR605 HGNC:HGNC:32861|Ensembl:ENSG00000207813|miRBase:MI0003618 +693191 MIR606 HGNC:HGNC:32862|Ensembl:ENSG00000207583|miRBase:MI0003619 +693192 MIR607 HGNC:HGNC:32863|Ensembl:ENSG00000207976|miRBase:MI0003620 +693193 MIR608 HGNC:HGNC:32864|Ensembl:ENSG00000207551|miRBase:MI0003621 +693194 MIR609 HGNC:HGNC:32865|Ensembl:ENSG00000208033|miRBase:MI0003622 +693195 MIR610 MIM:612330|HGNC:HGNC:32866|Ensembl:ENSG00000207874|miRBase:MI0003623 +693196 MIR611 HGNC:HGNC:32867|Ensembl:ENSG00000284108|miRBase:MI0003624 +693197 MIR612 HGNC:HGNC:32868|Ensembl:ENSG00000283791|miRBase:MI0003625 +693198 MIR613 HGNC:HGNC:32869|Ensembl:ENSG00000207983|miRBase:MI0003626 +693199 MIR614 HGNC:HGNC:32870|Ensembl:ENSG00000283759|miRBase:MI0003627 +693200 MIR615 HGNC:HGNC:32871|Ensembl:ENSG00000207571|miRBase:MI0003628 +693201 MIR616 MIM:614489|HGNC:HGNC:32872|Ensembl:ENSG00000208028|miRBase:MI0003629 +693202 MIR617 HGNC:HGNC:32873|Ensembl:ENSG00000207763|miRBase:MI0003631 +693203 MIR618 HGNC:HGNC:32874|Ensembl:ENSG00000208022|miRBase:MI0003632 +693204 MIR619 HGNC:HGNC:32875|Ensembl:ENSG00000207622|miRBase:MI0003633 +693205 MIR620 HGNC:HGNC:32876|Ensembl:ENSG00000207967|miRBase:MI0003634 +693206 MIR621 HGNC:HGNC:32877|Ensembl:ENSG00000207652|miRBase:MI0003635 +693207 MIR622 HGNC:HGNC:32878|Ensembl:ENSG00000283783|miRBase:MI0003636 +693208 MIR623 HGNC:HGNC:32879|Ensembl:ENSG00000207719|miRBase:MI0003637 +693209 MIR624 HGNC:HGNC:32880|Ensembl:ENSG00000207952|miRBase:MI0003638 +693210 MIR625 HGNC:HGNC:32881|Ensembl:ENSG00000207781|miRBase:MI0003639 +693211 MIR626 HGNC:HGNC:32882|Ensembl:ENSG00000207766|miRBase:MI0003640 +693212 MIR627 HGNC:HGNC:32883|Ensembl:ENSG00000207712|miRBase:MI0003641 +693213 MIR628 HGNC:HGNC:32884|Ensembl:ENSG00000283891|miRBase:MI0003642 +693214 MIR629 HGNC:HGNC:32885|Ensembl:ENSG00000207965|miRBase:MI0003643 +693215 MIR630 HGNC:HGNC:32886|Ensembl:ENSG00000283798|miRBase:MI0003644 +693216 MIR631 HGNC:HGNC:32887|Ensembl:ENSG00000284343|miRBase:MI0003645 +693217 MIR632 HGNC:HGNC:32888|Ensembl:ENSG00000283774|miRBase:MI0003647 +693218 MIR633 HGNC:HGNC:32889|Ensembl:ENSG00000207552|miRBase:MI0003648 +693219 MIR634 HGNC:HGNC:32890|Ensembl:ENSG00000207943|miRBase:MI0003649 +693220 MIR635 HGNC:HGNC:32891|Ensembl:ENSG00000207561|miRBase:MI0003650 +693221 MIR636 HGNC:HGNC:32892|Ensembl:ENSG00000283805|miRBase:MI0003651 +693222 MIR637 HGNC:HGNC:32893|Ensembl:ENSG00000283928|miRBase:MI0003652 +693223 MIR638 HGNC:HGNC:32894|Ensembl:ENSG00000207972|miRBase:MI0003653 +693224 MIR639 HGNC:HGNC:32895|Ensembl:ENSG00000283822|miRBase:MI0003654 +693225 MIR640 HGNC:HGNC:32896|Ensembl:ENSG00000207821|miRBase:MI0003655 +693226 MIR641 HGNC:HGNC:32897|Ensembl:ENSG00000207631|miRBase:MI0003656 +693227 MIR642A HGNC:HGNC:32898|Ensembl:ENSG00000207773|miRBase:MI0003657 +693228 MIR643 HGNC:HGNC:32899|Ensembl:ENSG00000208002|miRBase:MI0003658 +693229 MIR644A HGNC:HGNC:32900|Ensembl:ENSG00000207997|miRBase:MI0003659 +693230 MIR645 HGNC:HGNC:32901|Ensembl:ENSG00000208018|miRBase:MI0003660 +693231 MIR646 HGNC:HGNC:32902|Ensembl:ENSG00000207802|miRBase:MI0003661 +693232 MIR647 HGNC:HGNC:32903|Ensembl:ENSG00000207554|miRBase:MI0003662 +693233 MIR648 MIM:616205|HGNC:HGNC:32904|Ensembl:ENSG00000207780|miRBase:MI0003663 +693234 MIR649 HGNC:HGNC:32905|Ensembl:ENSG00000207575|miRBase:MI0003664 +693235 MIR92B HGNC:HGNC:32920|Ensembl:ENSG00000284586|miRBase:MI0003560 +723778 MIR650 MIM:615379|HGNC:HGNC:32906|Ensembl:ENSG00000284049|miRBase:MI0003665 +723779 MIR651 HGNC:HGNC:32907|Ensembl:ENSG00000207628|miRBase:MI0003666 +723788 MIG7 - +723790 HIST2H2AA4 HGNC:HGNC:29668|Ensembl:ENSG00000272196|Vega:OTTHUMG00000012097 +723805 LOC723805 - +723809 LHFPL3-AS2 HGNC:HGNC:44106|Ensembl:ENSG00000225329 +723961 INS-IGF2 HGNC:HGNC:33527|Ensembl:ENSG00000129965|Vega:OTTHUMG00000166213 +723972 ANP32AP1 HGNC:HGNC:42949|Ensembl:ENSG00000259516 +724022 MIR652 HGNC:HGNC:32908|Ensembl:ENSG00000208013|miRBase:MI0003667 +724023 MIR653 HGNC:HGNC:32909|Ensembl:ENSG00000208014|miRBase:MI0003674 +724024 MIR654 HGNC:HGNC:32910|Ensembl:ENSG00000207934|miRBase:MI0003676 +724025 MIR655 HGNC:HGNC:32911|Ensembl:ENSG00000207646|miRBase:MI0003677 +724026 MIR656 MIM:616376|HGNC:HGNC:32912|Ensembl:ENSG00000207959|miRBase:MI0003678 +724027 MIR657 HGNC:HGNC:32913|Ensembl:ENSG00000207736|miRBase:MI0003681 +724028 MIR658 HGNC:HGNC:32914|Ensembl:ENSG00000284197|miRBase:MI0003682 +724029 MIR659 MIM:613556|HGNC:HGNC:32915|Ensembl:ENSG00000207696|miRBase:MI0003683 +724030 MIR660 HGNC:HGNC:32916|Ensembl:ENSG00000207970|miRBase:MI0003684 +724031 MIR661 MIM:613716|HGNC:HGNC:32917|Ensembl:ENSG00000207574|miRBase:MI0003669 +724032 MIR662 HGNC:HGNC:32918|Ensembl:ENSG00000207579|miRBase:MI0003670 +724033 MIR663A HGNC:HGNC:32919|Ensembl:ENSG00000284419|miRBase:MI0003672 +724034 CEND1P2 HGNC:HGNC:43675 +724038 BDP1P HGNC:HGNC:31044 +724058 ANIB4 MIM:610213|HGNC:HGNC:31943 +724059 TMEM97P2 HGNC:HGNC:39641 +724060 LOC724060 - +724065 LOC724065 - +724066 ATXN8 MIM:613289|HGNC:HGNC:32925 +724067 DEFA7P HGNC:HGNC:31798 +724068 DEFA11P HGNC:HGNC:33354|Ensembl:ENSG00000234178 +724074 DFNY1 MIM:400043|HGNC:HGNC:26547 +724084 LOC724084 - +724085 LOC724085 - +724087 LINC01545 HGNC:HGNC:17986|Ensembl:ENSG00000204904 +724094 FAM27D1 HGNC:HGNC:32015 +724101 SS18L2P2 HGNC:HGNC:44966 +724102 SNHG4 HGNC:HGNC:32964 +724104 LOC724104 - +724105 LOC724105 - +724107 SPG32 MIM:611252|HGNC:HGNC:32314 +724110 SPG34 MIM:300750|HGNC:HGNC:32944 +727676 SNORD118 MIM:616663|HGNC:HGNC:32952|Ensembl:ENSG00000200463 +727677 CASC8 HGNC:HGNC:45129|Ensembl:ENSG00000246228 +727681 LOC727681 - +727682 TAB3-AS1 HGNC:HGNC:20176 +727684 C1orf195 HGNC:HGNC:32332 +727686 SNURFL HGNC:HGNC:29543 +727699 LINC00163 MIM:610259|HGNC:HGNC:33165|Ensembl:ENSG00000234880 +727701 LINC00165 HGNC:HGNC:33166 +727703 IGFL1P1 HGNC:HGNC:32956 +727704 IGFL1P2 HGNC:HGNC:32957 +727708 SNORD116-19 HGNC:HGNC:33085|Ensembl:ENSG00000207460 +727709 LOC727709 - +727713 LOC727713 - +727714 SCAX2 MIM:302600|HGNC:HGNC:32973 +727715 SCAX3 MIM:301790|HGNC:HGNC:32974 +727716 SCAX4 MIM:301840|HGNC:HGNC:32975 +727736 SH3GL1P3 HGNC:HGNC:10837 +727747 RPL22P12 HGNC:HGNC:36345 +727751 LOC727751 - +727758 ROCK1P1 HGNC:HGNC:37832|Ensembl:ENSG00000263006 +727764 MAFIP HGNC:HGNC:31102|Ensembl:ENSG00000277400 +727768 TEKT4P1 HGNC:HGNC:37711 +727789 RWDD1P3 HGNC:HGNC:31794 +727792 RPL31P31 HGNC:HGNC:35678 +727795 HMGN2P5 HGNC:HGNC:33568 +727800 RNF208 HGNC:HGNC:25420|Ensembl:ENSG00000212864|Vega:OTTHUMG00000131782 +727803 LOC727803 - +727805 POM121L14P HGNC:HGNC:44414 +727810 RPL21P17 HGNC:HGNC:19416 +727821 RPL21P45 HGNC:HGNC:35983 +727826 RPS11P5 HGNC:HGNC:36312 +727828 TRIM64DP HGNC:HGNC:43974 +727830 SPATA31A3 HGNC:HGNC:32003|Ensembl:ENSG00000275969|Vega:OTTHUMG00000188260 +727831 RPL13AP8 HGNC:HGNC:36966 +727832 GOLGA6L6 HGNC:HGNC:37225|Ensembl:ENSG00000277322|Vega:OTTHUMG00000171663 +727833 IMPDH1P11 HGNC:HGNC:6054 +727835 RPL9P16 HGNC:HGNC:36851 +727837 SSX2B HGNC:HGNC:22263|Ensembl:ENSG00000268447|Vega:OTTHUMG00000021593 +727838 LOC727838 - +727842 RBBP4P4 HGNC:HGNC:42371 +727851 RGPD8 MIM:602752|HGNC:HGNC:9849|Ensembl:ENSG00000169629|Vega:OTTHUMG00000153289 +727856 DDX11L16 HGNC:HGNC:37115 +727857 BHLHA9 MIM:615416|HGNC:HGNC:35126|Ensembl:ENSG00000205899|Vega:OTTHUMG00000132192 +727859 C4BPAP1 HGNC:HGNC:1326 +727865 RPL9P32 HGNC:HGNC:36418 +727866 FAM156B HGNC:HGNC:31962|Ensembl:ENSG00000179304|Vega:OTTHUMG00000188219 +727874 LOC727874 - +727879 C1DP4 HGNC:HGNC:38028 +727884 LOC727884 - +727896 LOC727896 - +727897 MUC5B MIM:600770|HGNC:HGNC:7516|Ensembl:ENSG00000117983|Vega:OTTHUMG00000166494 +727905 SPATA31A5 HGNC:HGNC:32005|Ensembl:ENSG00000276581|Vega:OTTHUMG00000188283 +727909 GOLGA8Q HGNC:HGNC:44408 +727910 TLCD2 HGNC:HGNC:33522|Ensembl:ENSG00000185561|Vega:OTTHUMG00000132477 +727914 BMS1P16 HGNC:HGNC:49161 +727915 AGBL1-AS1 HGNC:HGNC:48617|Ensembl:ENSG00000260125 +727919 LOC727919 - +727924 LINC02203 HGNC:HGNC:53069|Ensembl:ENSG00000280709 +727930 LOC727930 - +727936 GXYLT2 MIM:613322|HGNC:HGNC:33383|Ensembl:ENSG00000172986|Vega:OTTHUMG00000158815 +727940 RHOXF2B HGNC:HGNC:33519|Ensembl:ENSG00000203989|Vega:OTTHUMG00000022288 +727941 SLC25A24P1 HGNC:HGNC:48933 +727944 LINC01874 HGNC:HGNC:52693 +727947 LOC727947 - +727951 RPS3AP16 HGNC:HGNC:36052 +727956 SDHAP2 HGNC:HGNC:27408|Ensembl:ENSG00000242086 +727957 MROH1 HGNC:HGNC:26958|Ensembl:ENSG00000179832|Vega:OTTHUMG00000165781 +727964 C2orf69P1 HGNC:HGNC:51800 +727969 TSPY16P HGNC:HGNC:37712 +727970 RPS3AP43 HGNC:HGNC:36684 +727978 LOC727978 - +727980 LOC727980 - +727982 LINC01249 HGNC:HGNC:49843|Ensembl:ENSG00000231532 +727984 RPL17P22 HGNC:HGNC:35761 +727987 FAM207CP HGNC:HGNC:42676 +727991 SLC35E1P1 HGNC:HGNC:42046 +727993 PDYN-AS1 HGNC:HGNC:53462|Ensembl:ENSG00000233896 +727997 RPS12P9 HGNC:HGNC:36719 +728002 RPL15P17 HGNC:HGNC:36852 +728005 AGAP13P HGNC:HGNC:23499 +728010 RPL35P3 HGNC:HGNC:35488 +728012 MCHR2-AS1 HGNC:HGNC:48980|Ensembl:ENSG00000229315 +728015 RPS7P15 HGNC:HGNC:48878 +728019 HNRNPA1P67 HGNC:HGNC:48797 +728022 DUX4L14 HGNC:HGNC:38673 +728023 H2AFZP3 HGNC:HGNC:38013 +728024 LOC728024 - +728026 LOC728026 - +728034 BMS1P14 HGNC:HGNC:49159 +728036 CT47A10 MIM:300789|HGNC:HGNC:33291|Ensembl:ENSG00000224089|Vega:OTTHUMG00000022309 +728039 SSR4P1 HGNC:HGNC:23131|Ensembl:ENSG00000235374 +728040 LINC02499 HGNC:HGNC:53484|Ensembl:ENSG00000250436 +728042 CT47A9 MIM:300788|HGNC:HGNC:33290|Ensembl:ENSG00000226600|Vega:OTTHUMG00000022319 +728045 PPBPP1 MIM:188035|HGNC:HGNC:9241 +728047 GOLGA8O HGNC:HGNC:44406|Ensembl:ENSG00000206127|Vega:OTTHUMG00000162878 +728048 LOC728048 - +728049 CT47A8 MIM:300787|HGNC:HGNC:33289|Ensembl:ENSG00000230347|Vega:OTTHUMG00000022318 +728056 IQSEC3P3 HGNC:HGNC:49850 +728062 CT47A6 MIM:300785|HGNC:HGNC:33287|Ensembl:ENSG00000226023|Vega:OTTHUMG00000022316 +728064 CUBNP1 HGNC:HGNC:44983 +728066 FAM133DP HGNC:HGNC:44192 +728072 CT47A5 MIM:300784|HGNC:HGNC:33286|Ensembl:ENSG00000237957|Vega:OTTHUMG00000022315 +728075 CT47A4 MIM:300783|HGNC:HGNC:33285|Ensembl:ENSG00000230594|Vega:OTTHUMG00000022314 +728081 LINC00290 HGNC:HGNC:38515|Ensembl:ENSG00000248197 +728082 CT47A3 MIM:300782|HGNC:HGNC:33284|Ensembl:ENSG00000236126|Vega:OTTHUMG00000022313 +728084 LINC02458 HGNC:HGNC:53394|Ensembl:ENSG00000246363 +728088 RPL15P18 HGNC:HGNC:36515 +728090 CT47A2 MIM:300781|HGNC:HGNC:33283|Ensembl:ENSG00000242362|Vega:OTTHUMG00000022312 +728095 LOC728095 - +728096 CT47A1 MIM:300780|HGNC:HGNC:33282|Ensembl:ENSG00000236371|Vega:OTTHUMG00000022311 +728097 FAM8A2P HGNC:HGNC:16373 +728098 LOC728098 - +728099 LOC728099 - +728106 RPL23AP50 HGNC:HGNC:35958 +728111 HMGN1P31 HGNC:HGNC:39375 +728113 ANXA8L1 HGNC:HGNC:23334|Ensembl:ENSG00000264230|Vega:OTTHUMG00000018131 +728115 FAM60CP HGNC:HGNC:31737 +728116 ZBTB8B HGNC:HGNC:37057|Ensembl:ENSG00000273274|Vega:OTTHUMG00000167087 +728118 NUTM2A HGNC:HGNC:23438|Ensembl:ENSG00000184923|Vega:OTTHUMG00000018670 +728121 CSPG4P12 HGNC:HGNC:48362 +728126 RPSAP30 HGNC:HGNC:35861 +728128 RPL7AP26 HGNC:HGNC:36815 +728130 NUTM2D HGNC:HGNC:23447|Ensembl:ENSG00000214562|Vega:OTTHUMG00000018672 +728131 RPS6P6 - +728132 TSPY9P HGNC:HGNC:37472 +728134 RPL23AP18 HGNC:HGNC:36726 +728137 TSPY3 HGNC:HGNC:33876|Ensembl:ENSG00000228927|Vega:OTTHUMG00000041535 +728138 LOC728138 - +728139 RPL7AP70 HGNC:HGNC:36752 +728143 CHCHD4P4 HGNC:HGNC:44492 +728145 LOC728145 Ensembl:ENSG00000275038|Vega:OTTHUMG00000166260 +728157 ANKRD20A6P HGNC:HGNC:37714 +728158 LOC728158 - +728162 ST13P11 HGNC:HGNC:38746 +728167 KRT8P31 HGNC:HGNC:39865 +728169 DUX4L16 HGNC:HGNC:37719 +728170 HNRNPA1P50 HGNC:HGNC:48780 +728175 LINC02363 HGNC:HGNC:53286|Ensembl:ENSG00000180712 +728179 RPL7AP36 HGNC:HGNC:36356 +728190 NUTM2A-AS1 HGNC:HGNC:45161|Ensembl:ENSG00000223482 +728192 LINC00460 HGNC:HGNC:42809 +728194 RSPH10B2 HGNC:HGNC:34385|Ensembl:ENSG00000169402|Vega:OTTHUMG00000151856 +728195 FGF7P4 HGNC:HGNC:33587 +728196 LOC728196 - +728202 RPL36AP7 HGNC:HGNC:31328 +728207 RPL23AP75 HGNC:HGNC:35975 +728215 FAM155A HGNC:HGNC:33877|Ensembl:ENSG00000204442|Vega:OTTHUMG00000017326 +728218 LINC00864 HGNC:HGNC:45163 +728224 KRTAP4-8 HGNC:HGNC:17230|Ensembl:ENSG00000204880|Vega:OTTHUMG00000133580 +728226 GGTLC3 MIM:612340|HGNC:HGNC:33426 +728228 LINC01433 HGNC:HGNC:50746|Ensembl:ENSG00000230176 +728229 TMEM191B HGNC:HGNC:33600|Ensembl:ENSG00000278558|Vega:OTTHUMG00000188353 +728231 UBTFL5 HGNC:HGNC:35405 +728233 PI4KAP1 HGNC:HGNC:33576|Ensembl:ENSG00000274602 +728234 HMGN2P16 HGNC:HGNC:31330 +728239 MAGED4 MIM:300702|HGNC:HGNC:23793|Ensembl:ENSG00000154545|Vega:OTTHUMG00000042235 +728244 RPS12P29 HGNC:HGNC:36206 +728248 ABCB10P3 HGNC:HGNC:31129 +728255 KRTAP1-4 MIM:608821|HGNC:HGNC:18904|Ensembl:ENSG00000204887|Vega:OTTHUMG00000133631 +728262 FAM157A HGNC:HGNC:34079 +728263 ALG1L7P HGNC:HGNC:44376 +728264 CARMN HGNC:HGNC:42872 +728269 MAGEA9B MIM:300764|HGNC:HGNC:31909|Ensembl:ENSG00000267978|Vega:OTTHUMG00000188533 +728276 CLEC19A HGNC:HGNC:34522|Ensembl:ENSG00000261210|Vega:OTTHUMG00000177218 +728279 KRTAP2-2 HGNC:HGNC:18905|Ensembl:ENSG00000214518|Vega:OTTHUMG00000133593 +728283 LOC728283 - +728290 LINC02027 HGNC:HGNC:52862|Ensembl:ENSG00000243694 +728294 D2HGDH MIM:609186|HGNC:HGNC:28358|Ensembl:ENSG00000180902|Vega:OTTHUMG00000151474 +728299 KRTAP19-8 HGNC:HGNC:33898|Ensembl:ENSG00000206102|Vega:OTTHUMG00000057787 +728300 KRT18P5 HGNC:HGNC:19259 +728307 LOC728307 - +728310 GOLGA6L7P HGNC:HGNC:37442|Ensembl:ENSG00000261649 +728311 RPL26P24 HGNC:HGNC:35774 +728315 RPL7AP31 HGNC:HGNC:36857 +728317 LOC728317 - +728318 KRTAP9-1 HGNC:HGNC:18912|Ensembl:ENSG00000240542|Vega:OTTHUMG00000133636 +728323 LINC01881 HGNC:HGNC:52700 +728324 CHCHD2P2 HGNC:HGNC:39586 +728325 HMGN1P21 HGNC:HGNC:39365 +728327 LOC728327 - +728333 NCOA4P2 HGNC:HGNC:52403 +728339 LOC728339 - +728340 GTF2H2C HGNC:HGNC:31394|Ensembl:ENSG00000183474|Vega:OTTHUMG00000162365 +728342 LINC00992 HGNC:HGNC:48943 +728343 NXF2B HGNC:HGNC:23984|Ensembl:ENSG00000269437|Vega:OTTHUMG00000154920 +728344 GLRX3P2 HGNC:HGNC:49788 +728350 EIF2S2P4 HGNC:HGNC:37626 +728358 DEFA1B HGNC:HGNC:33596|Ensembl:ENSG00000240247|Vega:OTTHUMG00000149850 +728361 OVOL3 MIM:616442|HGNC:HGNC:14186|Ensembl:ENSG00000105261|Vega:OTTHUMG00000181748 +728365 RPL6P16 HGNC:HGNC:35674 +728366 BCLAF1P1 HGNC:HGNC:51329 +728369 USP17L24 HGNC:HGNC:44453|Ensembl:ENSG00000232264|Vega:OTTHUMG00000160201 +728373 USP17L25 HGNC:HGNC:44452|Ensembl:ENSG00000230430|Vega:OTTHUMG00000160192 +728374 RPL9P21 HGNC:HGNC:35886 +728376 LOC728376 - +728377 ARHGEF34P HGNC:HGNC:38086 +728378 POTEF HGNC:HGNC:33905|Ensembl:ENSG00000196604|Vega:OTTHUMG00000153628 +728379 USP17L26 HGNC:HGNC:44454|Ensembl:ENSG00000229579|Vega:OTTHUMG00000160189 +728380 RPL7P26 HGNC:HGNC:36630 +728381 NRBF2P4 HGNC:HGNC:44607 +728386 USP17L5 HGNC:HGNC:37177|Ensembl:ENSG00000227140|Vega:OTTHUMG00000160182 +728388 DNM1P30 HGNC:HGNC:35177 +728392 LOC728392 - +728393 USP17L27 HGNC:HGNC:44455|Ensembl:ENSG00000235780|Vega:OTTHUMG00000160186 +728395 TSPY4 HGNC:HGNC:37287|Ensembl:ENSG00000233803|Vega:OTTHUMG00000041529 +728400 USP17L28 HGNC:HGNC:44456|Ensembl:ENSG00000231051|Vega:OTTHUMG00000160191 +728402 TPI1P3 HGNC:HGNC:38070 +728403 TSPY8 HGNC:HGNC:37471|Ensembl:ENSG00000229549|Vega:OTTHUMG00000041531 +728405 USP17L29 HGNC:HGNC:44457|Ensembl:ENSG00000231637|Vega:OTTHUMG00000160183 +728407 PARGP1 HGNC:HGNC:45008 +728409 LINC01548 HGNC:HGNC:1296|Ensembl:ENSG00000229086 +728410 DUX4L2 HGNC:HGNC:37267 +728411 GUSBP1 HGNC:HGNC:13670|Ensembl:ENSG00000183666 +728416 LOC728416 - +728417 LOC728417 - +728418 POM121L7P HGNC:HGNC:35444 +728419 USP17L30 HGNC:HGNC:44458|Ensembl:ENSG00000228856|Vega:OTTHUMG00000160199 +728424 LOC728424 - +728428 RPS15P1 HGNC:HGNC:35725 +728430 FAM90A20P MIM:613054|HGNC:HGNC:32268 +728431 LINC01137 HGNC:HGNC:49453|Ensembl:ENSG00000233621 +728432 ICE2P2 HGNC:HGNC:48857 +728433 FGF7P7 HGNC:HGNC:33589 +728434 C20orf187 HGNC:HGNC:16180 +728441 GGT2 MIM:137181|HGNC:HGNC:4251|Ensembl:ENSG00000133475|Vega:OTTHUMG00000150617 +728447 TEX28P1 HGNC:HGNC:33356 +728448 PPIEL HGNC:HGNC:33195 +728450 LINC00687 HGNC:HGNC:16194|Ensembl:ENSG00000228422 +728452 LOC728452 - +728453 RPS28P6 HGNC:HGNC:36085 +728458 OPN1MW2 HGNC:HGNC:26952|Ensembl:ENSG00000166160|Vega:OTTHUMG00000024231 +728463 TGFB2-AS1 HGNC:HGNC:50628|Ensembl:ENSG00000232480 +728464 METTL24 HGNC:HGNC:21566|Ensembl:ENSG00000053328|Vega:OTTHUMG00000015359 +728467 SNX5P2 HGNC:HGNC:41513 +728468 BCRP6 HGNC:HGNC:39074 +728470 LOC728470 - +728477 GOLGA2P8 HGNC:HGNC:49922 +728481 RPL23AP21 HGNC:HGNC:35827 +728484 RPL23AP61 HGNC:HGNC:36016 +728485 LOC728485 - +728486 RPL7AP64 HGNC:HGNC:35821 +728488 LOC728488 - +728489 DNLZ HGNC:HGNC:33879|Ensembl:ENSG00000213221|Vega:OTTHUMG00000020931 +728492 SERF1B HGNC:HGNC:10756|Ensembl:ENSG00000205572|Vega:OTTHUMG00000162391 +728493 DPPA3P1 HGNC:HGNC:32345 +728495 FAM74A3 HGNC:HGNC:32031 +728498 GOLGA8H HGNC:HGNC:37443|Ensembl:ENSG00000261794|Vega:OTTHUMG00000175654 +728499 LOC728499 - +728501 RPL21P75 HGNC:HGNC:36460 +728505 WDR82P1 HGNC:HGNC:32447 +728506 LOC728506 - +728509 RPS19P7 HGNC:HGNC:35550 +728513 PNMA6B HGNC:HGNC:26681 +728517 RPL23AP24 HGNC:HGNC:36176 +728519 LOC728519 - +728523 RPL9P17 HGNC:HGNC:36337 +728524 SPDYE8P HGNC:HGNC:33771 +728526 LOC728526 - +728532 DYNC1I2P1 HGNC:HGNC:45012 +728533 LOC728533 - +728535 LOC728535 - +728537 LINC01125 HGNC:HGNC:49272|Ensembl:ENSG00000228486 +728538 RPL23AP77 HGNC:HGNC:36354 +728540 LOC728540 - +728549 LOC728549 - +728553 RPS8P8 HGNC:HGNC:36213 +728554 LOC728554 Ensembl:ENSG00000170089 +728556 MEMO1P1 HGNC:HGNC:23274 +728558 ENTPD1-AS1 HGNC:HGNC:45203|Ensembl:ENSG00000226688 +728562 RPSAP45 HGNC:HGNC:35857 +728564 GMPSP1 HGNC:HGNC:39428 +728567 RPL23AP48 HGNC:HGNC:36110 +728568 C12orf73 HGNC:HGNC:34450|Ensembl:ENSG00000204954|Vega:OTTHUMG00000170119 +728572 RPL32P11 HGNC:HGNC:35723 +728575 LOC728575 - +728576 RPL15P7 HGNC:HGNC:36808 +728577 CNTNAP3B HGNC:HGNC:32035|Ensembl:ENSG00000154529|Vega:OTTHUMG00000013174 +728586 CCDC192 HGNC:HGNC:49566|Ensembl:ENSG00000230561|Vega:OTTHUMG00000163284 +728587 LOC728587 - +728588 MS4A18 HGNC:HGNC:37636|Ensembl:ENSG00000214782|Vega:OTTHUMG00000167687 +728589 NAP1L4P1 HGNC:HGNC:39740 +728590 RPS27AP11 HGNC:HGNC:36126 +728591 CCDC169 HGNC:HGNC:34361|Ensembl:ENSG00000242715|Vega:OTTHUMG00000016731 +728597 DCDC2C HGNC:HGNC:32696|Ensembl:ENSG00000214866|Vega:OTTHUMG00000151490 +728599 CIAPIN1P HGNC:HGNC:31087 +728602 LOC728602 - +728606 PCAT18 HGNC:HGNC:49211|Ensembl:ENSG00000265369 +728609 SDHAP3 HGNC:HGNC:18781 +728611 BMS1P10 HGNC:HGNC:49154 +728613 LOC728613 - +728614 DNAJA1P4 HGNC:HGNC:39340 +728615 CICP13 HGNC:HGNC:37907 +728619 ASB9P1 HGNC:HGNC:20972 +728620 RPL7P22 HGNC:HGNC:35802 +728621 CCDC30 HGNC:HGNC:26103|Ensembl:ENSG00000186409|Vega:OTTHUMG00000007334 +728622 SKP1P2 MIM:601435|HGNC:HGNC:10900 +728629 TPI1P4 HGNC:HGNC:38071 +728632 HMGN2P3 HGNC:HGNC:33566 +728633 GTF2F2P2 HGNC:HGNC:39092 +728635 DHRS4L1 MIM:615195|HGNC:HGNC:19732 +728637 MEIKIN MIM:616232|HGNC:HGNC:51253|Ensembl:ENSG00000239642|Vega:OTTHUMG00000059633 +728638 KRT8P3 HGNC:HGNC:31056 +728640 FAM133CP HGNC:HGNC:44190 +728641 FABP5P7 HGNC:HGNC:31070 +728642 CDK11A MIM:116951|HGNC:HGNC:1730|Ensembl:ENSG00000008128|Vega:OTTHUMG00000000703 +728643 HNRNPA1P33 HGNC:HGNC:44990|Ensembl:ENSG00000213412 +728655 HULC MIM:612210|HGNC:HGNC:34232|Ensembl:ENSG00000251164 +728656 DMRTC1B HGNC:HGNC:31686|Ensembl:ENSG00000184911|Vega:OTTHUMG00000021818 +728657 DUSP8P4 HGNC:HGNC:45002 +728658 RPL13AP5 HGNC:HGNC:23736|Ensembl:ENSG00000236552 +728660 LOC728660 - +728661 SLC35E2B HGNC:HGNC:33941|Ensembl:ENSG00000189339|Vega:OTTHUMG00000078639 +728664 API5P2 HGNC:HGNC:39070 +728666 PRELID1P1 HGNC:HGNC:43886 +728667 LOC728667 - +728673 LOC728673 Ensembl:ENSG00000170161 +728675 SMCO4P1 HGNC:HGNC:49559 +728688 LOC728688 - +728689 EIF3CL HGNC:HGNC:26347|Ensembl:ENSG00000205609|Vega:OTTHUMG00000097025 +728693 RPL21P105 HGNC:HGNC:36304 +728695 SPANXB1 MIM:300669|HGNC:HGNC:14329|Ensembl:ENSG00000227234|Vega:OTTHUMG00000022554 +728698 EIF4A1P4 HGNC:HGNC:37923 +728700 RPS3AP19 HGNC:HGNC:36467 +728706 SUGT1P2 HGNC:HGNC:31377 +728710 FAM177A1P1 HGNC:HGNC:34441 +728712 SPANXA2 MIM:300493|HGNC:HGNC:14328|Ensembl:ENSG00000203926|Vega:OTTHUMG00000022565 +728715 LOC728715 - +728716 LINC01346 HGNC:HGNC:50563 +728723 ZBED3-AS1 HGNC:HGNC:44188 +728724 LINC00977 HGNC:HGNC:48902|Ensembl:ENSG00000250400 +728729 FABP5P8 HGNC:HGNC:31063 +728730 LOC728730 Ensembl:ENSG00000231312 +728732 HNRNPA1P53 HGNC:HGNC:48783 +728734 NPIPB8 HGNC:HGNC:37490|Ensembl:ENSG00000255524|Vega:OTTHUMG00000166386 +728737 TATDN1P1 HGNC:HGNC:45058 +728739 LOC728739 - +728741 NPIPB6 HGNC:HGNC:37454|Ensembl:ENSG00000198156|Vega:OTTHUMG00000166319 +728743 LOC728743 - +728746 FAM90A17P HGNC:HGNC:32265 +728747 ANKRD20A4 HGNC:HGNC:31982|Ensembl:ENSG00000172014|Vega:OTTHUMG00000066855 +728748 THAP12P1 HGNC:HGNC:39563 +728752 LOC728752 Ensembl:ENSG00000267309 +728753 FAM90A19P MIM:613053|HGNC:HGNC:32267 +728755 LOC728755 - +728758 PIN4P1 HGNC:HGNC:44193 +728763 CROCC2 HGNC:HGNC:51677|Ensembl:ENSG00000226321|Vega:OTTHUMG00000151855 +728769 SCAMP1-AS1 HGNC:HGNC:50544|Ensembl:ENSG00000245556 +728770 DNM1P5 HGNC:HGNC:21122 +728773 PABPC1P2 HGNC:HGNC:8559 +728774 RPS15AP25 HGNC:HGNC:36848 +728776 HMGN1P37 HGNC:HGNC:39421 +728780 ANKDD1B HGNC:HGNC:32525|Ensembl:ENSG00000189045|Vega:OTTHUMG00000162490 +728782 RPL21P134 HGNC:HGNC:36006 +728788 ANKRD20A20P HGNC:HGNC:32319 +728791 RPS10P4 HGNC:HGNC:31364 +728798 FRMPD2B HGNC:HGNC:16843 +728806 NSFP1 HGNC:HGNC:31405 +728807 LOC728807 - +728811 LOC728811 - +728815 LOC728815 - +728819 C1GALT1C1L HGNC:HGNC:51617|Ensembl:ENSG00000223658|Vega:OTTHUMG00000152807 +728820 RPL29P15 HGNC:HGNC:36159 +728823 RPS26P53 HGNC:HGNC:35582 +728825 LOC728825 - +728833 FAM72D MIM:614712|HGNC:HGNC:33593|Ensembl:ENSG00000215784|Vega:OTTHUMG00000074801 +728841 NBPF8 MIM:613998|HGNC:HGNC:31990|Ensembl:ENSG00000270231 +728843 RPL7P20 HGNC:HGNC:36013 +728851 HMGN1P36 HGNC:HGNC:39380 +728853 LOC728853 - +728855 LINC00623 HGNC:HGNC:44252 +728858 C12orf71 HGNC:HGNC:34452|Ensembl:ENSG00000214700|Vega:OTTHUMG00000169274 +728873 PTMAP8 HGNC:HGNC:42437 +728877 LOC728877 - +728882 FAM182B HGNC:HGNC:34503 +728887 CCNB1IP1P1 HGNC:HGNC:37693 +728888 NPIPB11 HGNC:HGNC:37453|Ensembl:ENSG00000254206|Vega:OTTHUMG00000170467 +728911 CT45A2 MIM:300793|HGNC:HGNC:28400|Ensembl:ENSG00000271449|Vega:OTTHUMG00000022490 +728913 RCN1P2 HGNC:HGNC:39204 +728917 ABHD17AP1 HGNC:HGNC:28394 +728920 PDE4DIPP1 HGNC:HGNC:50867 +728921 HAUS1P1 HGNC:HGNC:43760 +728927 ZNF736 HGNC:HGNC:32467|Ensembl:ENSG00000234444|Vega:OTTHUMG00000156537 +728929 ELOA3B HGNC:HGNC:31007|Ensembl:ENSG00000278674|Vega:OTTHUMG00000188257 +728931 AMD1P3 HGNC:HGNC:51608 +728933 RPL23AP60 HGNC:HGNC:35966 +728937 RPS26P25 HGNC:HGNC:35730 +728938 SUB1P1 HGNC:HGNC:32300 +728945 PPIAL4F HGNC:HGNC:33999|Ensembl:ENSG00000279782|Vega:OTTHUMG00000189245 +728947 ZNF680P1 HGNC:HGNC:50379 +728953 RPS19P3 HGNC:HGNC:23560 +728957 ZNF705D HGNC:HGNC:33202|Ensembl:ENSG00000215343|Vega:OTTHUMG00000165474 +728962 RPL7P56 HGNC:HGNC:35588 +728963 RPS15AP10 HGNC:HGNC:37001 +728970 PPP1R2P4 HGNC:HGNC:16319 +728971 RPS27AP7 HGNC:HGNC:35735 +728975 LOC728975 Ensembl:ENSG00000254614 +728978 UNC5B-AS1 HGNC:HGNC:45096|Ensembl:ENSG00000237512 +728979 RPL10AP9 HGNC:HGNC:35947 +728989 LOC728989 - +728990 SLC9A3P3 HGNC:HGNC:33492 +728992 RPL7AP11 HGNC:HGNC:35242 +728996 METTL8P1 HGNC:HGNC:49856 +729004 RPL9P2 HGNC:HGNC:17049 +729009 FTH1P20 HGNC:HGNC:37639 +729012 SKA2P1 HGNC:HGNC:23122 +729013 ZBED5-AS1 HGNC:HGNC:48646|Ensembl:ENSG00000247271 +729020 RPEL1 HGNC:HGNC:45241|Ensembl:ENSG00000235376|Vega:OTTHUMG00000018980 +729023 NUTM2HP HGNC:HGNC:45017 +729025 SLC15A5 HGNC:HGNC:33455|Ensembl:ENSG00000188991|Vega:OTTHUMG00000168793 +729032 RPL36P20 HGNC:HGNC:44564 +729033 LOC729033 - +729040 LOC729040 Ensembl:ENSG00000234292 +729041 FAAHP1 HGNC:HGNC:50679 +729042 RPL29P3 HGNC:HGNC:23565 +729046 RPL17P50 HGNC:HGNC:45098 +729047 LOC729047 - +729050 KRT18P29 HGNC:HGNC:33398 +729056 LOC729056 - +729057 LOC729057 - +729059 TEX46 HGNC:HGNC:44651|Ensembl:ENSG00000227868|Vega:OTTHUMG00000003226 +729073 FAM92A1P1 HGNC:HGNC:32278 +729075 RPL36AP23 HGNC:HGNC:36002 +729079 RPSAP21 HGNC:HGNC:36928 +729080 LOC729080 - +729082 OIP5-AS1 HGNC:HGNC:43563 +729083 LINC02158 HGNC:HGNC:53019|Ensembl:ENSG00000225611 +729085 FAM198A HGNC:HGNC:24485|Ensembl:ENSG00000144649|Vega:OTTHUMG00000156449 +729086 LOC729086 - +729092 AGAP5 HGNC:HGNC:23467|Ensembl:ENSG00000172650|Vega:OTTHUMG00000018473 +729096 BMS1P4 HGNC:HGNC:23652|Ensembl:ENSG00000271816 +729097 RPS4XP14 HGNC:HGNC:36737 +729101 IMMP1LP1 HGNC:HGNC:51131 +729102 HNRNPA1P22 HGNC:HGNC:39540 +729119 HMGB2P1 HGNC:HGNC:39174 +729121 RGPD4-AS1 HGNC:HGNC:49273|Ensembl:ENSG00000230651 +729123 RPL7P21 HGNC:HGNC:36762 +729126 LOC729126 - +729131 KRT8P7 HGNC:HGNC:33361 +729138 RPLP1P2 HGNC:HGNC:36210 +729141 LOC729141 - +729146 RPL9P28 HGNC:HGNC:36445 +729148 NUS1P1 HGNC:HGNC:38472 +729150 RPS3AP14 HGNC:HGNC:35715 +729156 GTF2IRD1P1 HGNC:HGNC:44136|Ensembl:ENSG00000230583 +729159 LOC729159 Ensembl:ENSG00000278499|Vega:OTTHUMG00000189254 +729162 LOC729162 - +729163 FABP5P2 HGNC:HGNC:31060 +729171 ANKRD20A8P HGNC:HGNC:23666 +729176 KATNBL1P6 HGNC:HGNC:49056 +729177 NBAT1 MIM:616206|HGNC:HGNC:49075|Ensembl:ENSG00000260455 +729178 STXBP5-AS1 HGNC:HGNC:44183 +729182 FAM91A3P HGNC:HGNC:32273 +729188 RPS26P58 HGNC:HGNC:36571 +729196 UNC93B5 HGNC:HGNC:34051 +729198 ANAPC10P1 HGNC:HGNC:33976 +729200 LOC729200 - +729201 SPACA5B HGNC:HGNC:19142|Ensembl:ENSG00000171478|Vega:OTTHUMG00000021465 +729203 RPL31P30 HGNC:HGNC:35679 +729208 RPL21P14 HGNC:HGNC:31029 +729209 RPSAP26 HGNC:HGNC:36195 +729211 KRT18P15 HGNC:HGNC:32449 +729212 RPL13AP26 HGNC:HGNC:35492 +729215 RPL32P29 HGNC:HGNC:35771 +729217 LOC729217 - +729218 LOC729218 - +729220 FLJ45513 - +729222 LOC729222 - +729224 LOC729224 - +729230 CCR2 MIM:601267|HGNC:HGNC:1603|Ensembl:ENSG00000121807|Vega:OTTHUMG00000156466 +729233 PRR20B HGNC:HGNC:37220|Ensembl:ENSG00000204918|Vega:OTTHUMG00000184243 +729234 FAHD2CP HGNC:HGNC:44135|Ensembl:ENSG00000231584 +729236 RPS13P2 HGNC:HGNC:36364 +729238 SFTPA2 MIM:178642|HGNC:HGNC:10799|Ensembl:ENSG00000185303|Vega:OTTHUMG00000018566 +729240 PRR20C HGNC:HGNC:37221|Ensembl:ENSG00000229665|Vega:OTTHUMG00000184244 +729241 RPL21P117 HGNC:HGNC:35987 +729246 PRR20D HGNC:HGNC:37222|Ensembl:ENSG00000227151|Vega:OTTHUMG00000184245 +729248 ZBTB45P2 HGNC:HGNC:49228 +729249 KLHL2P1 HGNC:HGNC:44046 +729250 PRR20E HGNC:HGNC:37223|Ensembl:ENSG00000234278|Vega:OTTHUMG00000184246 +729252 KRT16P1 HGNC:HGNC:6420 +729254 LOC729254 - +729257 RPS24P4 HGNC:HGNC:35852 +729258 RPS11P6 HGNC:HGNC:36693 +729259 RPL17P43 HGNC:HGNC:35996 +729262 NUTM2B HGNC:HGNC:23445|Ensembl:ENSG00000188199 +729264 TP53TG3D HGNC:HGNC:44657|Ensembl:ENSG00000205456|Vega:OTTHUMG00000132469 +729274 RPS2P53 HGNC:HGNC:36690 +729277 RPL23AP47 HGNC:HGNC:36576 +729279 RPL28P5 HGNC:HGNC:35766 +729288 ZNF286B HGNC:HGNC:33241|Ensembl:ENSG00000249459 +729291 LOC729291 - +729293 RPS18P10 HGNC:HGNC:35566 +729296 LOC729296 - +729298 PCNPP3 HGNC:HGNC:41975 +729299 PMS2P8 HGNC:HGNC:33516 +729301 RPL17P9 HGNC:HGNC:36230 +729305 LOC729305 - +729307 LINC02510 HGNC:HGNC:53499 +729308 RPL31P45 HGNC:HGNC:36796 +729310 KYNUP2 HGNC:HGNC:39200 +729313 LOC729313 - +729316 LOC729316 - +729317 LOC729317 - +729321 KYNUP1 HGNC:HGNC:39199 +729323 KYNUP3 HGNC:HGNC:39201 +729327 MED28P7 HGNC:HGNC:45084 +729330 OC90 MIM:601658|HGNC:HGNC:8100|Ensembl:ENSG00000253117|Vega:OTTHUMG00000164672 +729332 RPL27P8 HGNC:HGNC:36012 +729334 LOC729334 - +729338 CETN4P HGNC:HGNC:35450 +729340 RPL17P36 HGNC:HGNC:36051 +729342 NPM1P46 HGNC:HGNC:45225 +729344 KRT8P24 HGNC:HGNC:33376 +729347 AKR1B1P3 HGNC:HGNC:422 +729348 LINC01873 HGNC:HGNC:52692|Ensembl:ENSG00000232164 +729349 RPL17P16 HGNC:HGNC:35939 +729355 TP53TG3B HGNC:HGNC:37202|Ensembl:ENSG00000261509|Vega:OTTHUMG00000176461 +729356 PRAMEF29P HGNC:HGNC:51891 +729359 PLIN4 MIM:613247|HGNC:HGNC:29393|Ensembl:ENSG00000167676|Vega:OTTHUMG00000167571 +729362 RPL36AP37 HGNC:HGNC:36969 +729366 HNRNPA1P51 HGNC:HGNC:48781 +729369 LOC729369 - +729374 RPS10P6 HGNC:HGNC:35765 +729375 FAM86HP HGNC:HGNC:42359 +729384 TRIM49D2 HGNC:HGNC:37217|Ensembl:ENSG00000233802|Vega:OTTHUMG00000167644 +729389 RPS6P25 HGNC:HGNC:35948 +729391 RFWD2P1 HGNC:HGNC:31900 +729392 POM121L6P HGNC:HGNC:31343 +729396 GAGE12J MIM:300733|HGNC:HGNC:17778|Ensembl:ENSG00000224659|Vega:OTTHUMG00000024137 +729399 SEPHS1P6 HGNC:HGNC:42168 +729402 RPL21P16 HGNC:HGNC:31396 +729403 GAPDHP61 HGNC:HGNC:4155 +729406 PPP1R14BP2 HGNC:HGNC:16329 +729408 GAGE2D MIM:300735|HGNC:HGNC:31959 +729409 C1GALT1P1 HGNC:HGNC:51614 +729412 PSMA6P2 HGNC:HGNC:39607 +729416 RPLP1P6 HGNC:HGNC:35809 +729420 LMO7DN HGNC:HGNC:44370|Ensembl:ENSG00000178734|Vega:OTTHUMG00000187426 +729422 GAGE12C MIM:300727|HGNC:HGNC:28402|Ensembl:ENSG00000237671|Vega:OTTHUMG00000024144 +729423 HNRNPA1P6 HGNC:HGNC:5032 +729428 GAGE12B HGNC:HGNC:26779|Ensembl:ENSG00000275113|Vega:OTTHUMG00000067394 +729431 GAGE12E MIM:300729|HGNC:HGNC:31905|Ensembl:ENSG00000216649|Vega:OTTHUMG00000024146 +729435 ATP6V1E1P3 HGNC:HGNC:858 +729438 CASTOR2 MIM:617033|HGNC:HGNC:37073|Ensembl:ENSG00000274070|Vega:OTTHUMG00000181541 +729440 CCDC61 HGNC:HGNC:33629|Ensembl:ENSG00000104983|Vega:OTTHUMG00000182488 +729442 GAGE12H MIM:300732|HGNC:HGNC:31908|Ensembl:ENSG00000224902|Vega:OTTHUMG00000024149 +729447 GAGE2A MIM:300720|HGNC:HGNC:4099|Ensembl:ENSG00000189064|Vega:OTTHUMG00000024143 +729449 RPL7P50 HGNC:HGNC:35816 +729450 SUSD2P2 HGNC:HGNC:35197 +729451 LOC729451 - +729453 PMS2P6 HGNC:HGNC:33514 +729454 DSTNP4 HGNC:HGNC:44548 +729458 MBD3L2B HGNC:HGNC:53435 +729461 LINC01660 HGNC:HGNC:52448|Ensembl:ENSG00000274044 +729467 HSD52 Ensembl:ENSG00000224609 +729468 PGM5P4 HGNC:HGNC:49605 +729475 RAD51AP2 HGNC:HGNC:34417|Ensembl:ENSG00000214842|Vega:OTTHUMG00000151761 +729480 RPL23AP5 HGNC:HGNC:14194 +729484 RPL21P18 HGNC:HGNC:28362 +729486 IL9RP3 HGNC:HGNC:6033 +729490 NCOR1P2 HGNC:HGNC:42997 +729493 GAPDHP38 HGNC:HGNC:37792 +729494 ARPC3P3 HGNC:HGNC:39432 +729495 ABHD17AP4 HGNC:HGNC:34042 +729496 LOC729496 - +729497 NCOA4P3 HGNC:HGNC:52404 +729500 RPL12P14 HGNC:HGNC:36495 +729501 ZNF962P HGNC:HGNC:39250 +729505 HMGN2P24 HGNC:HGNC:39389 +729506 LINC02226 HGNC:HGNC:53095|Ensembl:ENSG00000245729 +729515 TMEM242 HGNC:HGNC:17206|Ensembl:ENSG00000215712|Vega:OTTHUMG00000015893 +729522 AACSP1 HGNC:HGNC:18226|Ensembl:ENSG00000250420 +729524 FEM1AP4 HGNC:HGNC:39832 +729528 PRAMEF14 HGNC:HGNC:13576|Ensembl:ENSG00000204481|Vega:OTTHUMG00000007916 +729530 CNOT6LP1 HGNC:HGNC:32355 +729532 LOC729532 - +729533 FAM72A MIM:614710|HGNC:HGNC:24044|Ensembl:ENSG00000196550|Vega:OTTHUMG00000042552 +729535 FAM207BP HGNC:HGNC:39715 +729536 RPL34P31 HGNC:HGNC:36899 +729540 RGPD6 MIM:612709|HGNC:HGNC:32419|Ensembl:ENSG00000183054|Vega:OTTHUMG00000153196 +729557 LOC729557 - +729558 LOC729558 Ensembl:ENSG00000249690 +729561 NAP1L1P1 HGNC:HGNC:38004 +729564 HMGN2P41 HGNC:HGNC:39412 +729565 NDUFB8P2 HGNC:HGNC:33978 +729566 ZBTB8OSP1 HGNC:HGNC:19043 +729568 SUSD2P1 HGNC:HGNC:33889 +729574 FAM231A HGNC:HGNC:49427|Ensembl:ENSG00000237847|Vega:OTTHUMG00000189242 +729582 DIRC3 MIM:608262|HGNC:HGNC:17805 +729583 LINC01556 HGNC:HGNC:21195 +729587 FAM231C HGNC:HGNC:49508|Ensembl:ENSG00000268674 +729595 HMGB3P22 HGNC:HGNC:39314 +729597 SPDYE6 HGNC:HGNC:35465|Ensembl:ENSG00000260097|Vega:OTTHUMG00000157126 +729602 NPIPB1P HGNC:HGNC:37452 +729603 LOC729603 Ensembl:ENSG00000213073 +729608 RPF2P1 HGNC:HGNC:16186 +729609 LOC729609 - +729610 FAHD2P1 HGNC:HGNC:32441 +729611 RPL29P30 HGNC:HGNC:36601 +729614 FLJ37453 Ensembl:ENSG00000179743 +729617 RPL23AP74 HGNC:HGNC:36148 +729621 RPL36AP46 HGNC:HGNC:35812 +729627 PRR23A HGNC:HGNC:37172|Ensembl:ENSG00000206260|Vega:OTTHUMG00000160635 +729630 DYNLL1P7 HGNC:HGNC:49658 +729633 MRS2P2 HGNC:HGNC:33942 +729635 HMGB3P19 HGNC:HGNC:39311 +729646 RPL31P4 HGNC:HGNC:23546 +729648 ZNF812P HGNC:HGNC:33242 +729650 METTL15P3 HGNC:HGNC:39558 +729652 LOC729652 Ensembl:ENSG00000259895 +729654 LOC729654 - +729658 PACRG-AS3 HGNC:HGNC:52053 +729659 S100A11P1 HGNC:HGNC:10491 +729662 RPL22P3 HGNC:HGNC:36804 +729665 CCDC175 HGNC:HGNC:19847|Ensembl:ENSG00000151838|Vega:OTTHUMG00000171096 +729666 LDHAP5 HGNC:HGNC:6540 +729667 TRMT112P3 HGNC:HGNC:44022 +729668 GOLGA2P6 HGNC:HGNC:44948 +729673 PPIAP18 HGNC:HGNC:32454 +729674 LOC729674 - +729677 RPL7P16 HGNC:HGNC:36591 +729678 LINC00847 HGNC:HGNC:45050|Ensembl:ENSG00000245060 +729679 RPS2P51 HGNC:HGNC:36422 +729681 LOC729681 - +729682 KRT17P3 HGNC:HGNC:33697 +729683 LOC729683 - +729686 NPM1P42 HGNC:HGNC:45221 +729687 HMGN2P25 HGNC:HGNC:39392 +729689 FAM90A2P HGNC:HGNC:32250 +729707 LOC729707 - +729708 TPI1P1 HGNC:HGNC:35449 +729723 DNAJC27-AS1 HGNC:HGNC:42943|Ensembl:ENSG00000224165 +729727 RPL12P1 HGNC:HGNC:13976 +729732 LOC729732 Ensembl:ENSG00000283674 +729737 LOC729737 - +729739 LOC729739 Ensembl:ENSG00000260266 +729747 ZNF878 HGNC:HGNC:37246|Ensembl:ENSG00000257446|Vega:OTTHUMG00000169370 +729756 PRSS44 HGNC:HGNC:37324 +729759 OR4F29 HGNC:HGNC:31275|Ensembl:ENSG00000278566|Vega:OTTHUMG00000002860 +729760 RPL12P18 HGNC:HGNC:36750 +729764 RPL23AP45 HGNC:HGNC:36896 +729767 CEACAM18 HGNC:HGNC:31949|Ensembl:ENSG00000213822|Vega:OTTHUMG00000151557 +729769 UQCRHP2 HGNC:HGNC:38045 +729774 LOC729774 - +729779 PSAT1P3 HGNC:HGNC:43989 +729780 RPS10P8 HGNC:HGNC:36606 +729786 GOLGA8CP HGNC:HGNC:32375|Ensembl:ENSG00000181984 +729789 RPS15P5 HGNC:HGNC:35536 +729790 ARL6IP1P3 HGNC:HGNC:44972 +729798 RPL23AP63 HGNC:HGNC:35502 +729799 SEC14L1P1 HGNC:HGNC:44189|Ensembl:ENSG00000213693 +729800 LOC729800 - +729806 ZNF731P HGNC:HGNC:32471 +729809 DNM1P34 HGNC:HGNC:35181 +729815 LOC729815 - +729816 DHFRP2 HGNC:HGNC:2863 +729817 HNRNPA3P14 HGNC:HGNC:48760 +729828 ST13P20 HGNC:HGNC:38863 +729830 FAM160A1 HGNC:HGNC:34237|Ensembl:ENSG00000164142|Vega:OTTHUMG00000161675 +729835 LOC729835 - +729838 GGTLC4P HGNC:HGNC:33428 +729839 LOC729839 - +729842 RPS2P50 HGNC:HGNC:36034 +729852 UMAD1 HGNC:HGNC:48955|Ensembl:ENSG00000219545|Vega:OTTHUMG00000152007 +729856 LOC729856 - +729857 RGPD2 MIM:612705|HGNC:HGNC:32415|Ensembl:ENSG00000185304|Vega:OTTHUMG00000153276 +729859 LOC729859 - +729862 LSP1P3 HGNC:HGNC:39718 +729867 LOC729867 Ensembl:ENSG00000227741 +729870 LOC729870 - +729873 TBC1D3 MIM:607741|HGNC:HGNC:19031|Ensembl:ENSG00000274611|Vega:OTTHUMG00000188487 +729877 TBC1D3H MIM:610811|HGNC:HGNC:30708|Ensembl:ENSG00000274226|Vega:OTTHUMG00000188427 +729885 VN1R101P HGNC:HGNC:37424 +729894 ELMO2P1 HGNC:HGNC:38008 +729898 ZBTB8OSP2 HGNC:HGNC:30326 +729900 LOC729900 - +729903 RPS16P10 HGNC:HGNC:35739 +729909 RPL36AP26 HGNC:HGNC:36758 +729911 ANKRD34C-AS1 HGNC:HGNC:48618|Ensembl:ENSG00000259234 +729920 ISPD MIM:614631|HGNC:HGNC:37276|Ensembl:ENSG00000214960|Vega:OTTHUMG00000152447 +729927 RPS20P27 HGNC:HGNC:36154 +729930 LOC729930 - +729941 LOC729941 - +729944 ZNF75CP HGNC:HGNC:13148 +729945 LOC729945 - +729948 CDC26P1 HGNC:HGNC:22770 +729950 LINC01915 HGNC:HGNC:52734|Ensembl:ENSG00000265485 +729952 HMGB3P6 HGNC:HGNC:39283 +729955 RPL18AP5 HGNC:HGNC:36777 +729956 SHISA7 MIM:617328|HGNC:HGNC:35409|Ensembl:ENSG00000187902|Vega:OTTHUMG00000154240 +729960 LOC729960 - +729962 RPL21P71 HGNC:HGNC:36049 +729966 LOC729966 Ensembl:ENSG00000105650 +729967 MORN2 HGNC:HGNC:30166|Ensembl:ENSG00000188010|Vega:OTTHUMG00000128589 +729968 LOC729968 - +729970 LOC729970 Ensembl:ENSG00000235501 +729973 LOC729973 - +729974 RFPL4AL1 HGNC:HGNC:45147|Ensembl:ENSG00000229292|Vega:OTTHUMG00000165450 +729975 LINC01530 HGNC:HGNC:44320 +729978 NPIPB2 HGNC:HGNC:37451 +729987 LINC01776 HGNC:HGNC:52566|Ensembl:ENSG00000226053 +729991 BORCS8 MIM:616601|HGNC:HGNC:37247|Ensembl:ENSG00000064489|Ensembl:ENSG00000254901|Vega:OTTHUMG00000154572|Vega:OTTHUMG00000166546 +729992 ST13P1 HGNC:HGNC:38715 +729993 SHISA9 MIM:613346|HGNC:HGNC:37231|Ensembl:ENSG00000237515|Vega:OTTHUMG00000154258 +729998 LOC729998 - +729999 LOC729999 - +730005 SEC14L6 HGNC:HGNC:40047|Ensembl:ENSG00000214491|Vega:OTTHUMG00000151267 +730010 BRI3P1 HGNC:HGNC:33533 +730013 ABCC6P2 HGNC:HGNC:33353|Ensembl:ENSG00000255277 +730016 QRSL1P1 HGNC:HGNC:43667 +730021 LOC730021 - +730023 KRT8P13 HGNC:HGNC:33365 +730029 RPSAP19 HGNC:HGNC:36508 +730041 RHOQP2 HGNC:HGNC:37836 +730043 LOC730043 - +730051 ZNF814 HGNC:HGNC:33258|Ensembl:ENSG00000204514|Vega:OTTHUMG00000183519 +730052 UBE2V1P2 HGNC:HGNC:32648 +730058 DNM1P49 HGNC:HGNC:47040 +730061 RPL34P33 HGNC:HGNC:36666 +730066 VN1R103P HGNC:HGNC:37426 +730069 LOC730069 - +730070 RPL26P11 HGNC:HGNC:35768 +730076 LOC730076 - +730086 ALG1L15P HGNC:HGNC:44384 +730087 ZNF726 HGNC:HGNC:32462|Ensembl:ENSG00000213967|Vega:OTTHUMG00000167681 +730091 LINC00886 HGNC:HGNC:48572|Ensembl:ENSG00000240875 +730092 RRN3P1 HGNC:HGNC:30548 +730094 C16orf52 HGNC:HGNC:27087|Ensembl:ENSG00000185716|Vega:OTTHUMG00000131587 +730098 LOC730098 Ensembl:ENSG00000187186|Vega:OTTHUMG00000000449 +730100 LOC730100 Ensembl:ENSG00000231918 +730101 LOC730101 Ensembl:ENSG00000216775 +730102 LOC730102 Ensembl:ENSG00000242193 +730109 LINC01100 HGNC:HGNC:49224 +730110 LOC730110 - +730112 FAM166B HGNC:HGNC:34242|Ensembl:ENSG00000215187|Vega:OTTHUMG00000019858 +730129 LOC730129 - +730130 TMEM229A HGNC:HGNC:37279|Ensembl:ENSG00000234224|Vega:OTTHUMG00000154762 +730138 PFN1P1 HGNC:HGNC:42989 +730144 EIF1P3 HGNC:HGNC:49616 +730152 GSTA7P HGNC:HGNC:4631 +730153 NPIPB10P HGNC:HGNC:37455 +730159 TEX50 HGNC:HGNC:52382|Ensembl:ENSG00000232113|Vega:OTTHUMG00000040547 +730174 NAP1L4P3 HGNC:HGNC:39738 +730177 RPS26P16 HGNC:HGNC:35557 +730180 RBBP4P3 HGNC:HGNC:42370 +730183 LOC730183 - +730187 RPS10P9 HGNC:HGNC:36451 +730190 ZNF101P2 HGNC:HGNC:44942 +730196 VN1R64P HGNC:HGNC:37384 +730198 MEIS1-AS3 HGNC:HGNC:40369 +730202 LOC730202 - +730211 HSP90AA5P HGNC:HGNC:32535 +730213 RPL5P5 HGNC:HGNC:35564 +730222 LOC730222 - +730227 LINC01136 HGNC:HGNC:49452|Ensembl:ENSG00000233791 +730232 EEF1A1P32 HGNC:HGNC:37909 +730234 LOC730234 - +730239 ZDHHC20P4 HGNC:HGNC:39776 +730246 HNRNPA1P59 HGNC:HGNC:48789 +730249 ACOD1 MIM:615275|HGNC:HGNC:33904|Ensembl:ENSG00000102794|Vega:OTTHUMG00000017098 +730255 RPL17P8 HGNC:HGNC:35651 +730257 LOC730257 - +730262 PPIAL4E MIM:608608|HGNC:HGNC:33997|Ensembl:ENSG00000271567|Vega:OTTHUMG00000189244 +730268 LOC730268 - +730291 ZNF735 HGNC:HGNC:32466|Ensembl:ENSG00000223614|Vega:OTTHUMG00000156539 +730338 LOC730338 Ensembl:ENSG00000233539 +730394 GTF2H2C_2 HGNC:HGNC:35418 +730647 HINT1P1 HGNC:HGNC:18467 +730668 LOC730668 Ensembl:ENSG00000280424 +730747 RPL14P3 HGNC:HGNC:36638 +730755 KRTAP2-3 HGNC:HGNC:18906|Ensembl:ENSG00000212724|Vega:OTTHUMG00000133655 +730792 SFR1P2 HGNC:HGNC:51532 +730811 MYT1L-AS1 HGNC:HGNC:49274|Ensembl:ENSG00000225619 +730861 RPS3AP29 HGNC:HGNC:35531 +730888 DEPDC1P1 HGNC:HGNC:31125 +730971 LINC02447 HGNC:HGNC:53379 +730974 PRELID3BP7 HGNC:HGNC:49069 +730978 CICP5 HGNC:HGNC:37754 +730993 RPS3AP39 HGNC:HGNC:35490 +731075 LOC731075 - +731157 LOC731157 Ensembl:ENSG00000255647 +731220 RFX8 HGNC:HGNC:37253|Ensembl:ENSG00000196460|Vega:OTTHUMG00000130693 +731223 LINC01220 HGNC:HGNC:49664 +731275 LINC01347 HGNC:HGNC:50566|Ensembl:ENSG00000214837 +731308 DYNLL1P2 HGNC:HGNC:20724 +731424 MIR3945HG HGNC:HGNC:52002 +731605 BCLAF1P2 HGNC:HGNC:51807 +731631 LOC731631 - +731642 RPL18AP9 - +731656 LINC01348 HGNC:HGNC:50567 +731688 RPL21P120 HGNC:HGNC:35743 +731716 PRKRAP1 HGNC:HGNC:33447 +731741 RPL32P12 HGNC:HGNC:36600 +731755 LOC731755 - +731779 LINC01300 HGNC:HGNC:50460|Ensembl:ENSG00000253595 +731789 FAM238B HGNC:HGNC:44917 +732199 RPL29P21 HGNC:HGNC:36322 +732229 LOC732229 - +732253 TDRG1 MIM:615676|HGNC:HGNC:43642|Ensembl:ENSG00000204091 +732265 LOC732265 - +732275 LINC00917 HGNC:HGNC:48607|Ensembl:ENSG00000168367 +732448 CCDC58P3 HGNC:HGNC:45026 +732538 FBXO36P1 HGNC:HGNC:50363 +735301 SNHG9 HGNC:HGNC:33102|Ensembl:ENSG00000255198 +751071 METTL12 HGNC:HGNC:33113|Ensembl:ENSG00000214756|Vega:OTTHUMG00000167545 +751580 LINC00106 HGNC:HGNC:31843|Ensembl:ENSG00000236871 +751599 TPM3P7 HGNC:HGNC:39170 +751602 LOC751602 - +751603 LOC751603 - +751781 GLC1L HGNC:HGNC:33120 +751783 DFNB69 HGNC:HGNC:33121 +751798 AUNX1 MIM:300614|HGNC:HGNC:31916 +751837 LOC751837 - +752014 CEMP1 MIM:611113|HGNC:HGNC:32553|Ensembl:ENSG00000205923|Vega:OTTHUMG00000177160 +767557 SYS1-DBNDD2 HGNC:HGNC:33535|Ensembl:ENSG00000254806|Vega:OTTHUMG00000166214 +767558 LUZP6 MIM:611050|HGNC:HGNC:33955|Ensembl:ENSG00000267697|Vega:OTTHUMG00000180445 +767561 SNORD113-1 MIM:613650|HGNC:HGNC:32980|Ensembl:ENSG00000202191 +767562 SNORD113-2 HGNC:HGNC:32981|Ensembl:ENSG00000212384 +767563 SNORD113-3 HGNC:HGNC:32982|Ensembl:ENSG00000201700 +767564 SNORD113-4 HGNC:HGNC:32983|Ensembl:ENSG00000201672 +767565 SNORD113-5 HGNC:HGNC:32984|Ensembl:ENSG00000272474 +767566 SNORD113-6 HGNC:HGNC:32985|Ensembl:ENSG00000200215 +767567 SNORD113-7 HGNC:HGNC:32986|Ensembl:ENSG00000200632 +767568 SNORD113-8 HGNC:HGNC:32987|Ensembl:ENSG00000200367 +767569 SNORD113-9 HGNC:HGNC:32988|Ensembl:ENSG00000201950 +767575 MRX71 HGNC:HGNC:13367 +767577 SNORD114-1 MIM:613651|HGNC:HGNC:32989|Ensembl:ENSG00000199575 +767578 SNORD114-2 HGNC:HGNC:32990|Ensembl:ENSG00000200823 +767579 SNORD114-3 HGNC:HGNC:32991|Ensembl:ENSG00000201839 +767580 SNORD114-4 HGNC:HGNC:32992 +767581 SNORD114-5 HGNC:HGNC:32993|Ensembl:ENSG00000199798 +767582 SNORD114-6 HGNC:HGNC:32994|Ensembl:ENSG00000201263 +767583 SNORD114-7 HGNC:HGNC:32995|Ensembl:ENSG00000199390 +767584 SNORD114-8 HGNC:HGNC:32996 +767585 SNORD114-9 HGNC:HGNC:32997|Ensembl:ENSG00000201240 +767588 SNORD114-10 HGNC:HGNC:32998|Ensembl:ENSG00000200279 +767589 SNORD114-11 HGNC:HGNC:32999|Ensembl:ENSG00000200608 +767590 SNORD114-12 HGNC:HGNC:33000|Ensembl:ENSG00000202270 +767591 SNORD114-13 HGNC:HGNC:33001|Ensembl:ENSG00000201247 +767592 SNORD114-14 HGNC:HGNC:33002|Ensembl:ENSG00000199593 +767593 SNORD114-15 HGNC:HGNC:33003|Ensembl:ENSG00000201557 +767594 SNORD114-16 HGNC:HGNC:33004|Ensembl:ENSG00000199914 +767595 SNORD114-17 HGNC:HGNC:33005|Ensembl:ENSG00000201569 +767596 SNORD114-18 HGNC:HGNC:33006|Ensembl:ENSG00000202142 +767597 SNORD114-19 HGNC:HGNC:33007|Ensembl:ENSG00000199942 +767598 SNORD114-20 HGNC:HGNC:33008|Ensembl:ENSG00000202048 +767599 SNORD114-21 HGNC:HGNC:33009|Ensembl:ENSG00000272344 +767600 SNORD114-22 HGNC:HGNC:33010|Ensembl:ENSG00000202293 +767603 SNORD114-23 HGNC:HGNC:33011|Ensembl:ENSG00000200406 +767604 SNORD114-24 HGNC:HGNC:33012|Ensembl:ENSG00000201899 +767605 SNORD114-25 HGNC:HGNC:33013|Ensembl:ENSG00000200612 +767606 SNORD114-26 HGNC:HGNC:33014|Ensembl:ENSG00000200413 +767608 SNORD114-27 HGNC:HGNC:33015|Ensembl:ENSG00000200636 +767609 SNORD114-28 HGNC:HGNC:33016|Ensembl:ENSG00000200480 +767610 SNORD114-29 HGNC:HGNC:33017|Ensembl:ENSG00000201689 +767611 SNORD114-30 HGNC:HGNC:33018|Ensembl:ENSG00000201318 +767612 SNORD114-31 HGNC:HGNC:33019|Ensembl:ENSG00000200089 +767811 H2BFXP HGNC:HGNC:25757 +767846 PFN1P2 MIM:608609|HGNC:HGNC:24298|Ensembl:ENSG00000270392 +767850 PFN1P9 HGNC:HGNC:42991 +767851 PFN1P4 HGNC:HGNC:42992 +767853 PFN1P10 HGNC:HGNC:42985 +768086 TREHP1 HGNC:HGNC:51907 +768096 HAR1A MIM:610556|HGNC:HGNC:33117 +768097 HAR1B MIM:610557|HGNC:HGNC:33118|Ensembl:ENSG00000231133 +768206 PRCD MIM:610598|HGNC:HGNC:32528|Ensembl:ENSG00000214140|Vega:OTTHUMG00000132200 +768211 RELL1 MIM:611212|HGNC:HGNC:27379|Ensembl:ENSG00000181826|Vega:OTTHUMG00000160389 +768212 MIR758 HGNC:HGNC:33133|Ensembl:ENSG00000211582|miRBase:MI0003757 +768213 MIR671 MIM:615245|HGNC:HGNC:33134|Ensembl:ENSG00000284191|miRBase:MI0003760 +768214 MIR668 HGNC:HGNC:33135|Ensembl:ENSG00000276352|miRBase:MI0003761 +768215 MIR767 HGNC:HGNC:33136|Ensembl:ENSG00000211583|miRBase:MI0003763 +768216 MIR454 HGNC:HGNC:33137|Ensembl:ENSG00000211514|miRBase:MI0003820 +768217 MIR769 HGNC:HGNC:33138|Ensembl:ENSG00000211580|miRBase:MI0003834 +768218 MIR766 HGNC:HGNC:33139|Ensembl:ENSG00000211578|miRBase:MI0003836 +768219 MIR802 MIM:616090|HGNC:HGNC:33140|Ensembl:ENSG00000211590|miRBase:MI0003906 +768220 MIR765 HGNC:HGNC:33141|Ensembl:ENSG00000211581|miRBase:MI0005116 +768222 MIR770 HGNC:HGNC:33143|Ensembl:ENSG00000211574|miRBase:MI0005118 +768239 PSAPL1 HGNC:HGNC:33131|Ensembl:ENSG00000178597|Vega:OTTHUMG00000160006 +768328 EIF4EBP1P2 HGNC:HGNC:44047 +777642 RP34 MIM:300605|HGNC:HGNC:33161 +777643 GLC1M MIM:610535|HGNC:HGNC:33162 +777645 GLC1N MIM:611274|HGNC:HGNC:33163 +777650 LOC777650 - +777774 ACTR3BP4 HGNC:HGNC:38681 +777778 OPA6 MIM:258500|HGNC:HGNC:33170 +780776 TVP23A HGNC:HGNC:20398|Ensembl:ENSG00000166676|Vega:OTTHUMG00000177389 +780778 USP10P2 HGNC:HGNC:33272 +780779 USP10P1 HGNC:HGNC:31752 +780780 LOC780780 - +780789 C1orf196 HGNC:HGNC:32336 +780810 PAICSP3 HGNC:HGNC:38096 +780811 PAICSP5 HGNC:HGNC:38098 +780812 PAICSP6 HGNC:HGNC:38099 +780813 PAICSP4 HGNC:HGNC:38097 +780814 PAICSP1 HGNC:HGNC:8588 +780815 PAICSP2 HGNC:HGNC:8589 +780816 PAICSP7 HGNC:HGNC:38100 +780851 SNORD3A MIM:180710|HGNC:HGNC:33189|Ensembl:ENSG00000263934 +780852 SNORD3B-2 HGNC:HGNC:33190|Ensembl:ENSG00000262074 +780853 SNORD3C HGNC:HGNC:33191|Ensembl:ENSG00000264940 +780854 SNORD3D HGNC:HGNC:33192|Ensembl:ENSG00000277947|Ensembl:ENSG00000281000 +780895 DUPC1 MIM:126900 +780896 ACTD MIM:142700 +780897 HPP1 MIM:145250|HGNC:HGNC:37055 +780898 APMR1 MIM:203650 +780899 DIH2 MIM:222400 +780900 FGS5 MIM:300581|HGNC:HGNC:37735 +780901 NYS5 MIM:300589 +780903 HHT3 MIM:601101 +780904 PSS MIM:601224 +780905 EA3 MIM:606554 +780906 SLI3 MIM:607134 +780908 PEE2 MIM:609402 +780909 PEE3 MIM:609403 +780910 PPR2 MIM:609572 +780911 DEL10Q26 MIM:609625 +780912 AD10 MIM:609636 +780913 EIG4 MIM:609750 +780914 ZD1 MIM:609815 +780915 CHNG3 MIM:609893 +780916 GINGF3 MIM:609955|HGNC:HGNC:16333 +780917 NKCD MIM:609981 +780919 HRPT3 MIM:610071 +780920 MPD3 MIM:610099 +780921 KYPSC1 MIM:610170 +780922 SPD3 MIM:610234 +780923 IHPS2 MIM:610260 +780925 CHMRQ MIM:610185 +790951 TRS-AGA3-1 HGNC:HGNC:33201 +790952 ESRG MIM:611473|HGNC:HGNC:39079|Ensembl:ENSG00000265992 +790953 TSL - +790955 UQCC3 MIM:616097|HGNC:HGNC:34399|Ensembl:ENSG00000204922|Vega:OTTHUMG00000167546 +790966 TRK-CTT2-3 MIM:612996|HGNC:HGNC:33199 +790969 ZNF705F HGNC:HGNC:33204 +791082 DBIP3 HGNC:HGNC:38517 +791085 DEL17Q21.31 MIM:610443 +791086 CTPP5 MIM:610634 +791087 HHT4 MIM:610655 +791091 LOC791091 - +791092 LOC791092 - +791093 LOC791093 - +791095 LOC791095 - +791096 LOC791096 - +791097 LOC791097 - +791098 LOC791098 - +791114 PWRN1 MIM:611215|HGNC:HGNC:33235|Ensembl:ENSG00000259905 +791115 PWRN2 MIM:611217|HGNC:HGNC:33236 +791121 SHFL1 MIM:119100 +791122 KTWS MIM:149000 +791123 SHFLD2 MIM:610685 +791126 LOC791126 - +791226 TRN-GTT4-1 HGNC:HGNC:33197 +791227 TRN-GTT6-1 HGNC:HGNC:33198 +791228 SPG36 MIM:613096|HGNC:HGNC:33240 +791229 MACOM MIM:602499|HGNC:HGNC:33244 +791230 TRV-AAC1-5 HGNC:HGNC:33246 +791231 TRV-AAC3-1 HGNC:HGNC:33247 +791232 TRV-CAC1-3 HGNC:HGNC:33248 +791254 EDS8 MIM:130080 +791255 SPDA2 MIM:183840 +100008586 GAGE12F MIM:300730|HGNC:HGNC:31906|Ensembl:ENSG00000236362|Vega:OTTHUMG00000024147 +100008587 RNA5-8SN5 HGNC:HGNC:53533 +100008588 RNA18SN5 HGNC:HGNC:53531 +100008589 RNA28SN5 HGNC:HGNC:53532 +100009601 TRY-GTA7-1 HGNC:HGNC:33249 +100009602 TRY-GTA5-4 HGNC:HGNC:33250 +100009603 TRA-AGC11-1 HGNC:HGNC:33253 +100009604 TRA-AGC8-1 HGNC:HGNC:33254 +100009605 TRF-GAA2-1 HGNC:HGNC:33255 +100009606 TRF-GAA1-4 HGNC:HGNC:33259 +100009607 TRH-GTG1-6 HGNC:HGNC:33260 +100009613 ANO1-AS2 HGNC:HGNC:33275 +100009667 POU5F1P5 HGNC:HGNC:33311 +100009668 POU5F1P6 HGNC:HGNC:33312 +100009669 POU5F1P7 HGNC:HGNC:33313 +100009675 MRT4 MIM:611107|HGNC:HGNC:33243 +100009676 ZBTB11-AS1 HGNC:HGNC:48573|Ensembl:ENSG00000256628 +100033391 VN2R2P HGNC:HGNC:33208 +100033392 VN2R3P HGNC:HGNC:33209 +100033395 VN2R6P HGNC:HGNC:33212 +100033396 VN2R7P HGNC:HGNC:33213 +100033398 VN2R10P HGNC:HGNC:33216 +100033399 VN2R11P HGNC:HGNC:33217 +100033400 VN2R12P HGNC:HGNC:33218 +100033401 VN2R13P HGNC:HGNC:33219 +100033402 VN2R14P HGNC:HGNC:33220 +100033403 VN2R15P HGNC:HGNC:33221 +100033404 VN2R16P HGNC:HGNC:33222 +100033406 VN2R18P HGNC:HGNC:33224 +100033407 VN2R19P HGNC:HGNC:33225 +100033408 VN2R20P HGNC:HGNC:33226 +100033409 OTX2P1 HGNC:HGNC:33281 +100033411 DUXB HGNC:HGNC:33345 +100033413 SNORD116-1 MIM:605436|HGNC:HGNC:33067|Ensembl:ENSG00000207063 +100033414 SNORD116-2 HGNC:HGNC:33068|Ensembl:ENSG00000207001 +100033415 SNORD116-3 HGNC:HGNC:33069|Ensembl:ENSG00000207014 +100033416 SNORD116-4 HGNC:HGNC:33070|Ensembl:ENSG00000275529 +100033417 SNORD116-5 HGNC:HGNC:33071|Ensembl:ENSG00000207191 +100033418 SNORD116-6 HGNC:HGNC:33072|Ensembl:ENSG00000207442 +100033419 SNORD116-7 HGNC:HGNC:33073|Ensembl:ENSG00000207133 +100033420 SNORD116-8 HGNC:HGNC:33074|Ensembl:ENSG00000207093 +100033421 SNORD116-9 HGNC:HGNC:33075|Ensembl:ENSG00000206727 +100033422 SNORD116-10 HGNC:HGNC:33076|Ensembl:ENSG00000200661 +100033423 SNORD116-11 HGNC:HGNC:33077|Ensembl:ENSG00000206609 +100033424 SNORD116-12 HGNC:HGNC:33078|Ensembl:ENSG00000207197 +100033425 SNORD116-13 HGNC:HGNC:33079|Ensembl:ENSG00000207137 +100033426 SNORD116-14 HGNC:HGNC:33080|Ensembl:ENSG00000206621 +100033427 SNORD116-15 HGNC:HGNC:33081|Ensembl:ENSG00000207174 +100033428 SNORD116-16 HGNC:HGNC:33082|Ensembl:ENSG00000207263 +100033429 SNORD116-17 HGNC:HGNC:33083|Ensembl:ENSG00000206656 +100033430 SNORD116-18 HGNC:HGNC:33084|Ensembl:ENSG00000206688 +100033431 SNORD116-20 HGNC:HGNC:33086|Ensembl:ENSG00000278715 +100033432 SNORD116-21 HGNC:HGNC:33087|Ensembl:ENSG00000277785 +100033433 SNORD116-22 HGNC:HGNC:33088|Ensembl:ENSG00000275127 +100033434 SNORD116-23 HGNC:HGNC:33089|Ensembl:ENSG00000207375 +100033435 SNORD116-24 HGNC:HGNC:33090|Ensembl:ENSG00000207279 +100033436 SNORD116-25 HGNC:HGNC:33091|Ensembl:ENSG00000252326 +100033437 SNORD115-2 HGNC:HGNC:33021|Ensembl:ENSG00000199712 +100033438 SNORD116-26 HGNC:HGNC:33092|Ensembl:ENSG00000251815 +100033439 SNORD116-27 HGNC:HGNC:33093|Ensembl:ENSG00000251896 +100033440 SNORD115-3 HGNC:HGNC:33022|Ensembl:ENSG00000199970 +100033441 SNORD115-4 HGNC:HGNC:33023|Ensembl:ENSG00000200680 +100033442 SNORD115-5 HGNC:HGNC:33024|Ensembl:ENSG00000200503 +100033443 SNORD115-6 HGNC:HGNC:33025|Ensembl:ENSG00000200812 +100033444 SNORD115-7 HGNC:HGNC:33026|Ensembl:ENSG00000278089 +100033445 SNORD115-8 HGNC:HGNC:33027|Ensembl:ENSG00000200726 +100033446 SNORD115-9 HGNC:HGNC:33028|Ensembl:ENSG00000199782 +100033447 SNORD115-10 HGNC:HGNC:33029|Ensembl:ENSG00000201943 +100033448 SNORD115-11 HGNC:HGNC:33030|Ensembl:ENSG00000200486 +100033449 SNORD115-12 HGNC:HGNC:33031|Ensembl:ENSG00000199453 +100033450 SNORD115-13 HGNC:HGNC:33032|Ensembl:ENSG00000273835 +100033451 SNORD115-14 HGNC:HGNC:33033|Ensembl:ENSG00000199960 +100033453 SNORD115-15 HGNC:HGNC:33034|Ensembl:ENSG00000201679 +100033454 SNORD115-16 HGNC:HGNC:33035|Ensembl:ENSG00000200757 +100033455 SNORD115-17 HGNC:HGNC:33036|Ensembl:ENSG00000201482 +100033456 SNORD115-18 HGNC:HGNC:33037|Ensembl:ENSG00000200163 +100033458 SNORD115-19 HGNC:HGNC:33038|Ensembl:ENSG00000199968 +100033460 SNORD115-20 HGNC:HGNC:33039|Ensembl:ENSG00000201969 +100033603 SNORD115-21 HGNC:HGNC:33040|Ensembl:ENSG00000199833 +100033799 SNORD115-22 HGNC:HGNC:33041|Ensembl:ENSG00000201326 +100033800 SNORD115-23 HGNC:HGNC:33042|Ensembl:ENSG00000201331 +100033801 SNORD115-25 HGNC:HGNC:33044|Ensembl:ENSG00000199489 +100033802 SNORD115-26 HGNC:HGNC:33045|Ensembl:ENSG00000275524 +100033803 SNORD115-29 HGNC:HGNC:33048|Ensembl:ENSG00000199704 +100033804 SNORD115-30 HGNC:HGNC:33049|Ensembl:ENSG00000200987 +100033805 SNORD115-31 HGNC:HGNC:33050|Ensembl:ENSG00000202188 +100033806 SNORD115-32 HGNC:HGNC:33051|Ensembl:ENSG00000200949 +100033807 SNORD115-33 HGNC:HGNC:33052|Ensembl:ENSG00000200593 +100033808 SNORD115-34 HGNC:HGNC:33053|Ensembl:ENSG00000199311 +100033809 SNORD115-35 HGNC:HGNC:33054|Ensembl:ENSG00000201992 +100033810 SNORD115-36 HGNC:HGNC:33055|Ensembl:ENSG00000202499 +100033811 SNORD115-37 HGNC:HGNC:33056|Ensembl:ENSG00000200638 +100033812 SNORD115-38 HGNC:HGNC:33057|Ensembl:ENSG00000201907 +100033813 SNORD115-39 HGNC:HGNC:33058|Ensembl:ENSG00000200564 +100033814 SNORD115-40 HGNC:HGNC:33059|Ensembl:ENSG00000272460 +100033815 SNORD115-41 HGNC:HGNC:33060|Ensembl:ENSG00000200478 +100033816 SNORD115-42 HGNC:HGNC:33061|Ensembl:ENSG00000201143 +100033817 SNORD115-43 HGNC:HGNC:33062|Ensembl:ENSG00000202373 +100033818 SNORD115-44 HGNC:HGNC:33063|Ensembl:ENSG00000202261 +100033819 MIR675 MIM:615509|HGNC:HGNC:33351|Ensembl:ENSG00000284010|miRBase:MI0005416 +100033820 SNORD116-28 HGNC:HGNC:33347|Ensembl:ENSG00000278123 +100033821 SNORD116-29 HGNC:HGNC:33348|Ensembl:ENSG00000207245 +100033822 SNORD115-48 HGNC:HGNC:33343|Ensembl:ENSG00000201634 +100034700 AA1 MIM:104000 +100034703 AA2 MIM:610753 +100034704 RHDNS1 MIM:610805 +100034705 MMVP3 MIM:610840 +100034743 PDZK1P1 HGNC:HGNC:31974 +100036563 SNORD115-24 HGNC:HGNC:33043|Ensembl:ENSG00000200398 +100036564 SNORD115-27 HGNC:HGNC:33046|Ensembl:ENSG00000201300 +100036565 SNORD115-28 HGNC:HGNC:33047|Ensembl:ENSG00000200801 +100036566 SNORD115-45 HGNC:HGNC:33064 +100036567 SNORD115-47 HGNC:HGNC:33065 +100036574 HMGN1P3 HGNC:HGNC:23343 +100036575 HMGN1P4 HGNC:HGNC:39336 +100037264 STQTL6 MIM:300591 +100037265 STQTL7 MIM:609822 +100037266 STQTL8 MIM:610114 +100037267 LOC100037267 - +100037280 UBE2D3P1 HGNC:HGNC:33349 +100037417 DDTL HGNC:HGNC:33446|Ensembl:ENSG00000099974|Vega:OTTHUMG00000150800 +100038246 TLX1NB MIM:612734|HGNC:HGNC:37183|Ensembl:ENSG00000236311 +100038247 PTLS MIM:610883 +100038248 PSNP3 MIM:610898 +100048903 MCCD1P1 HGNC:HGNC:33449 +100048904 DDX39BP1 HGNC:HGNC:33450 +100048905 GBD2 MIM:609918|HGNC:HGNC:33452 +100048906 GBD3 MIM:609919|HGNC:HGNC:33453 +100048907 ZDHHC20P1 HGNC:HGNC:33456 +100048908 ZDHHC20P2 HGNC:HGNC:33457 +100048909 TMEM183AP1 HGNC:HGNC:33458 +100048912 CDKN2B-AS1 MIM:613149|HGNC:HGNC:34341|Ensembl:ENSG00000240498 +100048922 RPL35AP4 HGNC:HGNC:33460 +100048923 DDX39BP2 HGNC:HGNC:33461 +100048924 MCCD1P2 HGNC:HGNC:33462 +100049076 GUSBP9 HGNC:HGNC:42323 +100049159 SPG37 MIM:611945|HGNC:HGNC:33472 +100049160 FEB7 MIM:611515|HGNC:HGNC:33479 +100049541 STUT1 MIM:184450 +100049542 SHFM3 MIM:246560 +100049543 STUT2 MIM:609261 +100049544 APMR2 MIM:610422 +100049579 OCTN3 - +100049587 SIGLEC14 HGNC:HGNC:32926|Ensembl:ENSG00000254415|Vega:OTTHUMG00000165511 +100049613 TRK-TTT3-4 HGNC:HGNC:33256 +100049614 TRV-CAC1-5 HGNC:HGNC:33245 +100049707 SPG38 MIM:612335|HGNC:HGNC:33485 +100049716 LOC100049716 Ensembl:ENSG00000177406 +100049717 JKAMPP1 HGNC:HGNC:49759 +100073347 MIMT1 HGNC:HGNC:33464|Ensembl:ENSG00000268654 +100093624 CDH12P3 HGNC:HGNC:37699 +100093625 CDH12P1 HGNC:HGNC:37698 +100093626 CDH12P4 HGNC:HGNC:37700 +100093630 SNHG8 HGNC:HGNC:33098|Ensembl:ENSG00000269893 +100093631 GTF2IP4 HGNC:HGNC:51716|Ensembl:ENSG00000233369 +100093632 DFNA57 HGNC:HGNC:33491 +100093698 GS1-600G8.3 Ensembl:ENSG00000231216 +100093716 DFNB75 HGNC:HGNC:33503 +100101111 GXYLT1P1 HGNC:HGNC:39676 +100101112 CDC14BL - +100101115 TTTY21B HGNC:HGNC:37980|Ensembl:ENSG00000237563 +100101116 TTTY1B HGNC:HGNC:37981|Ensembl:ENSG00000129816 +100101117 TTTY2B HGNC:HGNC:37982 +100101118 TTTY8B HGNC:HGNC:37622|Ensembl:ENSG00000185700 +100101119 SKP1P3 HGNC:HGNC:50370 +100101120 TTTY7B HGNC:HGNC:37463|Ensembl:ENSG00000147761 +100101121 TTTY23B HGNC:HGNC:37983|Ensembl:ENSG00000237069 +100101126 LOC100101126 - +100101127 LOC100101127 - +100101148 LOC100101148 - +100101246 LOC100101246 - +100101247 LOC100101247 - +100101266 HAVCR1P1 HGNC:HGNC:44033|Ensembl:ENSG00000268442 +100101267 POM121C MIM:615754|HGNC:HGNC:34005|Ensembl:ENSG00000272391|Vega:OTTHUMG00000156238 +100101268 SPDYE12P HGNC:HGNC:51508 +100101405 TMA16P1 HGNC:HGNC:43780 +100101407 TMA16P2 HGNC:HGNC:43781 +100101423 MRT8 MIM:611094|HGNC:HGNC:39147 +100101424 MRT9 MIM:611095|HGNC:HGNC:39148 +100101425 MRT10 MIM:611096|HGNC:HGNC:39149 +100101426 MRT11 MIM:611097|HGNC:HGNC:39150 +100101440 PMS2P7 HGNC:HGNC:33515 +100101467 ZSCAN30 HGNC:HGNC:33517|Ensembl:ENSG00000186814|Vega:OTTHUMG00000178569 +100101478 LOC100101478 - +100101483 LOC100101483 - +100101490 MCTS2P HGNC:HGNC:49760 +100101554 BRI3P3 HGNC:HGNC:32544 +100101629 GAGE8 MIM:300638|HGNC:HGNC:4106 +100101917 ELF2P1 HGNC:HGNC:33539 +100101932 GNG5P3 HGNC:HGNC:33552 +100101933 GNG5P4 HGNC:HGNC:33553 +100101935 GNG5P5 HGNC:HGNC:33554 +100101938 ANKRD26P3 HGNC:HGNC:39689 +100113373 HMGN2P17 HGNC:HGNC:39381 +100113374 LOC100113374 - +100113375 LOC100113375 - +100113378 SNORD119 HGNC:HGNC:33558 +100113379 SNORD121A HGNC:HGNC:33560|Ensembl:ENSG00000238886 +100113380 SNORD125 HGNC:HGNC:33564|Ensembl:ENSG00000239127 +100113381 SNORD19B HGNC:HGNC:33570|Ensembl:ENSG00000238862 +100113382 SNORD105B HGNC:HGNC:33572|Ensembl:ENSG00000238531 +100113384 SNORD123 HGNC:HGNC:33562 +100113386 UCKL1-AS1 HGNC:HGNC:31967 +100113389 SNORD127 HGNC:HGNC:33555|Ensembl:ENSG00000239043 +100113391 SNORD126 HGNC:HGNC:33565 +100113392 SNORD11B HGNC:HGNC:33571|Ensembl:ENSG00000271852 +100113393 SNORD12B HGNC:HGNC:33573|Ensembl:ENSG00000222365 +100113397 LOC100113397 - +100113402 SNORD111B HGNC:HGNC:33579 +100113403 LIN28B-AS1 HGNC:HGNC:21553|Ensembl:ENSG00000203809 +100113404 LINC00583 HGNC:HGNC:31437|Ensembl:ENSG00000205636 +100113407 TMEM170B HGNC:HGNC:34244|Ensembl:ENSG00000205269|Vega:OTTHUMG00000014259 +100113421 FGF7P8 HGNC:HGNC:34516 +100114903 NRBF2P2 HGNC:HGNC:44605 +100118954 NRBF2P5 HGNC:HGNC:44683 +100124332 YBX2P1 HGNC:HGNC:49498 +100124334 LOC100124334 - +100124373 LOC100124373 - +100124394 KLF3P2 HGNC:HGNC:41519 +100124401 LOC100124401 - +100124402 LOC100124402 - +100124412 FAM138E HGNC:HGNC:32335|Ensembl:ENSG00000248893 +100124414 GINGF4 MIM:611010|HGNC:HGNC:37734 +100124415 EKD2 MIM:611031 +100124516 SNORD58C HGNC:HGNC:33613 +100124533 SCARNA27 HGNC:HGNC:33614 +100124534 SNORA84 HGNC:HGNC:33615|Ensembl:ENSG00000239183 +100124535 SNORA36C HGNC:HGNC:33616|Ensembl:ENSG00000207016 +100124536 SNORA38B HGNC:HGNC:33617|Ensembl:ENSG00000200394 +100124537 SNORA70B HGNC:HGNC:33618|Ensembl:ENSG00000206937 +100124538 SNORA70C HGNC:HGNC:33619|Ensembl:ENSG00000207268 +100124539 SNORA11B HGNC:HGNC:33620|Ensembl:ENSG00000221102 +100124540 SNORA11C HGNC:HGNC:33621|Ensembl:ENSG00000221459 +100124541 SNORA11D HGNC:HGNC:33622|Ensembl:ENSG00000221475 +100124696 TEC MIM:227050 +100124700 HOTAIR MIM:611400|HGNC:HGNC:33510|Ensembl:ENSG00000228630 +100125288 ZGLP1 MIM:611639|HGNC:HGNC:37245|Ensembl:ENSG00000220201|Vega:OTTHUMG00000152114 +100125387 HNRNPRP1 HGNC:HGNC:44907 +100125392 LOC100125392 - +100125393 LOC100125393 - +100125409 LOC100125409 - +100125556 FAM86JP HGNC:HGNC:44097|Ensembl:ENSG00000171084 +100126007 L1TD1P1 HGNC:HGNC:49127 +100126008 NUDT19P1 HGNC:HGNC:43585 +100126270 FMR1-AS1 MIM:300805|HGNC:HGNC:39081|Ensembl:ENSG00000268066 +100126296 MIR298 MIM:614914|HGNC:HGNC:33634|Ensembl:ENSG00000216031|miRBase:MI0005523 +100126297 MIR300 HGNC:HGNC:33636|Ensembl:ENSG00000215957|miRBase:MI0005525 +100126299 VTRNA2-1 MIM:614938|HGNC:HGNC:37054|Ensembl:ENSG00000270123|Ensembl:ENSG00000278815 +100126301 MIR509-2 HGNC:HGNC:33641|Ensembl:ENSG00000212013|miRBase:MI0005530 +100126302 MIR450B HGNC:HGNC:33642|Ensembl:ENSG00000216001|miRBase:MI0005531 +100126303 MIR890 HGNC:HGNC:33644|Ensembl:ENSG00000216075|miRBase:MI0005533 +100126304 MIR891B HGNC:HGNC:33645|Ensembl:ENSG00000216064|miRBase:MI0005534 +100126306 MIR888 HGNC:HGNC:33648|Ensembl:ENSG00000216005|miRBase:MI0005537 +100126307 MIR892B HGNC:HGNC:33649|Ensembl:ENSG00000216098|miRBase:MI0005538 +100126308 MIR541 HGNC:HGNC:33650|Ensembl:ENSG00000216179|miRBase:MI0005539 +100126309 MIR875 HGNC:HGNC:33652|Ensembl:ENSG00000216069|miRBase:MI0005541 +100126310 MIR876 HGNC:HGNC:33653|Ensembl:ENSG00000215966|miRBase:MI0005542 +100126311 MIR147B HGNC:HGNC:33655|Ensembl:ENSG00000284386|miRBase:MI0005544 +100126313 MIR744 HGNC:HGNC:33658|Ensembl:ENSG00000266297|miRBase:MI0005559 +100126314 MIR877 MIM:611619|HGNC:HGNC:33660|Ensembl:ENSG00000216101|miRBase:MI0005561 +100126315 MIR665 HGNC:HGNC:33662|Ensembl:ENSG00000283159|miRBase:MI0005563 +100126316 MIR873 MIM:616137|HGNC:HGNC:33663|Ensembl:ENSG00000215939|miRBase:MI0005564 +100126317 MIR374B HGNC:HGNC:33665|Ensembl:ENSG00000212027|miRBase:MI0005566 +100126318 MIR301B HGNC:HGNC:33667|Ensembl:ENSG00000212102|miRBase:MI0005568 +100126319 MIR216B HGNC:HGNC:33668|Ensembl:ENSG00000211520|miRBase:MI0005569 +100126320 MIR920 HGNC:HGNC:33670|Ensembl:ENSG00000216192|miRBase:MI0005712 +100126321 MIR922 HGNC:HGNC:33672|Ensembl:ENSG00000284146|miRBase:MI0005714 +100126323 MIR924 HGNC:HGNC:33674|Ensembl:ENSG00000283615|miRBase:MI0005716 +100126324 MIR934 HGNC:HGNC:33677|Ensembl:ENSG00000216060|miRBase:MI0005756 +100126325 MIR935 HGNC:HGNC:33678|Ensembl:ENSG00000284583|miRBase:MI0005757 +100126326 MIR936 HGNC:HGNC:33679|Ensembl:ENSG00000283788|miRBase:MI0005758 +100126327 MIR938 HGNC:HGNC:33681|Ensembl:ENSG00000216035|miRBase:MI0005760 +100126328 MIR940 HGNC:HGNC:33683|Ensembl:ENSG00000284346|miRBase:MI0005762 +100126329 MIR941-1 HGNC:HGNC:33684|Ensembl:ENSG00000283206|miRBase:MI0005763 +100126330 MIR941-4 HGNC:HGNC:33687|Ensembl:ENSG00000216195|miRBase:MI0005766 +100126331 MIR942 HGNC:HGNC:33688|Ensembl:ENSG00000215930|miRBase:MI0005767 +100126332 MIR943 HGNC:HGNC:33689|Ensembl:ENSG00000284587|miRBase:MI0005768 +100126333 MIR708 HGNC:HGNC:33654|Ensembl:ENSG00000211997|miRBase:MI0005543 +100126334 MIR885 HGNC:HGNC:33659|Ensembl:ENSG00000216135|miRBase:MI0005560 +100126335 MIR543 HGNC:HGNC:33664|Ensembl:ENSG00000212040|miRBase:MI0005565 +100126336 MIR208B MIM:613613|HGNC:HGNC:33669|Ensembl:ENSG00000215991|miRBase:MI0005570 +100126337 MIR509-3 MIM:300876|HGNC:HGNC:33675|Ensembl:ENSG00000212014|miRBase:MI0005717 +100126338 MIR937 HGNC:HGNC:33680|Ensembl:ENSG00000284224|miRBase:MI0005759 +100126339 MIR941-2 HGNC:HGNC:33685|Ensembl:ENSG00000216141|miRBase:MI0005764 +100126340 MIR944 HGNC:HGNC:33690|Ensembl:ENSG00000216058|miRBase:MI0005769 +100126341 MIR891A HGNC:HGNC:33635|Ensembl:ENSG00000216056|miRBase:MI0005524 +100126342 MIR892A HGNC:HGNC:33639|Ensembl:ENSG00000215943|miRBase:MI0005528 +100126343 MIR874 HGNC:HGNC:33643|Ensembl:ENSG00000216009|miRBase:MI0005532 +100126345 MIR889 HGNC:HGNC:33651|Ensembl:ENSG00000216099|miRBase:MI0005540 +100126346 MIR190B HGNC:HGNC:33656|Ensembl:ENSG00000215938|miRBase:MI0005545 +100126347 MIR887 HGNC:HGNC:33661|Ensembl:ENSG00000216077|miRBase:MI0005562 +100126348 MIR760 HGNC:HGNC:33666|Ensembl:ENSG00000211575|miRBase:MI0005567 +100126349 MIR921 HGNC:HGNC:33671|Ensembl:ENSG00000215952|miRBase:MI0005713 +100126350 MIR933 HGNC:HGNC:33676|Ensembl:ENSG00000215973|miRBase:MI0005755 +100126351 MIR939 HGNC:HGNC:33682|Ensembl:ENSG00000284310|miRBase:MI0005761 +100126352 MIR941-3 HGNC:HGNC:33686|Ensembl:ENSG00000283513|miRBase:MI0005765 +100126354 MIR297 MIM:615520|HGNC:HGNC:33691|Ensembl:ENSG00000215961|miRBase:MI0005775 +100126355 MIR365A MIM:614735|HGNC:HGNC:33692|Ensembl:ENSG00000199130|miRBase:MI0000767 +100126356 MIR365B HGNC:HGNC:33693|Ensembl:ENSG00000283978|miRBase:MI0000769 +100126446 DEPDC1P2 HGNC:HGNC:33975 +100126447 LOC100126447 - +100126572 GJE1 HGNC:HGNC:33251 +100126584 LOC100126584 - +100126593 MAFD4 MIM:611247 +100126594 EJM4 MIM:611364 +100126595 MGS MIM:611376 +100126596 CUX2P1 HGNC:HGNC:33694 +100126597 CUX2P2 HGNC:HGNC:33695 +100126693 LINC00322 HGNC:HGNC:33698 +100126780 SNAR-G1 HGNC:HGNC:34327 +100126781 SNAR-F HGNC:HGNC:34326 +100126784 LOC100126784 - +100126791 EGOT MIM:611662|HGNC:HGNC:37129|Ensembl:ENSG00000235947 +100126793 GHRLOS HGNC:HGNC:33885|Ensembl:ENSG00000240288 +100126794 GAEC1 MIM:612130 +100126798 SNAR-A1 HGNC:HGNC:34304 +100126799 SNAR-A2 HGNC:HGNC:34305 +100126800 SNAR-A12 HGNC:HGNC:34315 +100126822 LOC100126822 - +100126825 GJA6P HGNC:HGNC:32542 +100127050 VN2R21P HGNC:HGNC:33938 +100127173 HLA-Y HGNC:HGNC:33913 +100127206 KIAA1024L HGNC:HGNC:33914|Ensembl:ENSG00000186367|Vega:OTTHUMG00000163041 +100127883 IBTKP1 HGNC:HGNC:31672 +100127888 SLCO4A1-AS1 HGNC:HGNC:40537|Ensembl:ENSG00000232803 +100127892 LOC100127892 - +100127893 RPL7P24 HGNC:HGNC:36715 +100127900 LOC100127900 - +100127902 BMI1P1 HGNC:HGNC:51428 +100127903 LOC100127903 - +100127905 SMIM11P1 HGNC:HGNC:21400 +100127906 PQLC1P2 HGNC:HGNC:43987 +100127907 HNRNPCP7 HGNC:HGNC:48818 +100127908 LOC100127908 - +100127911 ST13P12 HGNC:HGNC:38787 +100127912 LOC100127912 - +100127917 LOC100127917 - +100127919 LOC100127919 - +100127922 SUMO2P6 HGNC:HGNC:39016 +100127924 RPS15AP14 HGNC:HGNC:36629 +100127934 LOC100127934 - +100127938 LOC100127938 - +100127945 SOCS5P3 HGNC:HGNC:44599 +100127949 RPL15P16 HGNC:HGNC:36067 +100127950 HECW1-IT1 HGNC:HGNC:41465|Ensembl:ENSG00000181211 +100127952 ATF4P4 HGNC:HGNC:787 +100127954 LOC100127954 - +100127955 LOC100127955 - +100127958 AGGF1P9 HGNC:HGNC:51746 +100127960 BCAS2P1 HGNC:HGNC:39594 +100127962 LOC100127962 - +100127963 RPS3AP48 HGNC:HGNC:36792 +100127965 LOC100127965 - +100127967 KRT73-AS1 HGNC:HGNC:49607|Ensembl:ENSG00000257495 +100127969 VN1R96P HGNC:HGNC:37416 +100127976 VTI1BP3 HGNC:HGNC:43729 +100127978 LOC100127978 - +100127979 FUNDC2P4 HGNC:HGNC:37971 +100127981 LOC100127981 - +100127982 LOC100127982 - +100127983 C8orf88 HGNC:HGNC:44672|Ensembl:ENSG00000253250|Vega:OTTHUMG00000164011 +100127986 LOC100127986 - +100127989 MED15P4 HGNC:HGNC:48653 +100127993 RPL15P5 HGNC:HGNC:35746 +100127995 RPL34P7 HGNC:HGNC:35575 +100127999 RPL18AP11 HGNC:HGNC:36661 +100128002 LOC100128002 - +100128004 RPL32P21 HGNC:HGNC:36363 +100128006 LOC100128006 Ensembl:ENSG00000265489 +100128007 LOC100128007 - +100128010 SUMO2P17 HGNC:HGNC:49358 +100128011 FAR1P1 HGNC:HGNC:39675 +100128012 ISCA1P4 HGNC:HGNC:38025 +100128015 HMGN1P26 HGNC:HGNC:39370 +100128016 WHSC1L2P HGNC:HGNC:14647 +100128017 TULP3P1 HGNC:HGNC:39262 +100128020 ACTR3P3 HGNC:HGNC:38679 +100128022 LOC100128022 - +100128023 DPPA2P3 HGNC:HGNC:44628 +100128025 WWTR1-AS1 HGNC:HGNC:41035|Ensembl:ENSG00000241313 +100128027 LOC100128027 - +100128028 LOC100128028 - +100128029 KNOP1P3 HGNC:HGNC:48921 +100128030 RPL10P11 HGNC:HGNC:36565 +100128033 PIGPP3 HGNC:HGNC:45155 +100128036 KLF7P1 HGNC:HGNC:17207 +100128041 KRT19P4 HGNC:HGNC:45073 +100128042 BRD7P6 HGNC:HGNC:37632 +100128043 FAF2P1 HGNC:HGNC:45172 +100128044 HNRNPA1P11 HGNC:HGNC:39129 +100128048 LOC100128048 - +100128050 LOC100128050 - +100128052 LOC100128052 - +100128054 PLCE1-AS1 HGNC:HGNC:45193|Ensembl:ENSG00000268894 +100128055 SMARCA5-AS1 HGNC:HGNC:39982|Ensembl:ENSG00000245112 +100128056 LOC100128056 - +100128057 NIPA2P3 HGNC:HGNC:42043 +100128059 LOC100128059 - +100128060 RPS7P10 HGNC:HGNC:39903 +100128061 HNRNPDLP2 HGNC:HGNC:48753 +100128062 SLC2A3P1 HGNC:HGNC:11008 +100128071 FAM229A HGNC:HGNC:44652|Ensembl:ENSG00000225828|Vega:OTTHUMG00000007587 +100128072 RPL36AP27 HGNC:HGNC:35650 +100128076 LOC100128076 - +100128078 LOC100128078 - +100128079 LOC100128079 - +100128081 JAZF1-AS1 HGNC:HGNC:41218 +100128083 RPS15AP40 HGNC:HGNC:36041 +100128086 LOC100128086 - +100128091 LOC100128091 - +100128092 PRDX3P2 HGNC:HGNC:39265 +100128093 LOC100128093 - +100128094 LPCAT2BP HGNC:HGNC:38003 +100128098 ST8SIA6-AS1 HGNC:HGNC:44880|Ensembl:ENSG00000204832 +100128102 PHBP16 HGNC:HGNC:51549 +100128103 AGGF1P5 HGNC:HGNC:51741 +100128108 LOC100128108 - +100128109 MEF2BNBP1 HGNC:HGNC:49883 +100128110 CHCHD2P3 HGNC:HGNC:39587 +100128115 RPL26P35 HGNC:HGNC:36278 +100128117 RPL17P15 HGNC:HGNC:36889 +100128118 CCNHP1 HGNC:HGNC:50854 +100128119 SLC25A51P3 HGNC:HGNC:31051 +100128121 LOC100128121 - +100128122 LOC100128122 - +100128124 HGC6.3 - +100128126 STAU2-AS1 HGNC:HGNC:44101|Ensembl:ENSG00000253302 +100128127 ADGRA1-AS1 HGNC:HGNC:49543 +100128132 TMCC1P1 HGNC:HGNC:31901 +100128135 GVINP2 HGNC:HGNC:38876 +100128136 NDUFA5P4 HGNC:HGNC:48846 +100128139 LINC01233 HGNC:HGNC:49756|Ensembl:ENSG00000269364 +100128140 RPS4XP17 HGNC:HGNC:36789 +100128144 LOC100128144 - +100128145 CLCP2 HGNC:HGNC:42536 +100128154 MFSD4BP1 HGNC:HGNC:50626 +100128159 ATF1P1 HGNC:HGNC:37691 +100128162 RPS6P7 HGNC:HGNC:36092 +100128164 LOC100128164 Ensembl:ENSG00000239219 +100128168 RPS26P39 HGNC:HGNC:36958 +100128171 LOC100128171 - +100128174 DEFB131C HGNC:HGNC:38060 +100128176 UST-AS1 HGNC:HGNC:40802 +100128177 NDUFS5P5 HGNC:HGNC:44043 +100128179 RAP1BP2 HGNC:HGNC:49781 +100128181 FMO10P HGNC:HGNC:32211 +100128183 PABPC1P7 HGNC:HGNC:37987 +100128190 SLC9B1P1 HGNC:HGNC:37492 +100128191 TMPO-AS1 HGNC:HGNC:44158|Ensembl:ENSG00000257167 +100128203 ENSAP3 HGNC:HGNC:37946 +100128210 LOC100128210 - +100128217 GTF3AP5 HGNC:HGNC:49748 +100128218 PSMC6P3 HGNC:HGNC:34012 +100128220 EDDM3DP HGNC:HGNC:37707 +100128227 HMGB1P20 HGNC:HGNC:39103 +100128233 LINC02324 HGNC:HGNC:53244|Ensembl:ENSG00000255002 +100128237 YRDCP2 HGNC:HGNC:39920 +100128238 LOC100128238 - +100128239 LOC100128239 Ensembl:ENSG00000204241 +100128240 CD83P1 HGNC:HGNC:13946 +100128242 LOC100128242 - +100128248 LOC100128248 - +100128250 RPL31P55 HGNC:HGNC:36982 +100128252 ZNF667-AS1 HGNC:HGNC:44321|Ensembl:ENSG00000166770 +100128253 LOC100128253 - +100128254 FAM90A28P HGNC:HGNC:43747 +100128258 RPS18P3 HGNC:HGNC:36198 +100128260 WASIR1 HGNC:HGNC:38513 +100128262 TNK2-AS1 HGNC:HGNC:49093 +100128264 HTR5A-AS1 HGNC:HGNC:48956|Ensembl:ENSG00000220575 +100128266 RANP6 HGNC:HGNC:39861 +100128268 LOC100128268 - +100128275 SYF2P2 HGNC:HGNC:38139 +100128276 LOC100128276 - +100128277 RPL35AP20 HGNC:HGNC:36053 +100128284 LOC100128284 - +100128285 DNM1P35 HGNC:HGNC:35182 +100128288 LOC100128288 - +100128292 DLG5-AS1 HGNC:HGNC:45109 +100128293 LOC100128293 - +100128297 LOC100128297 - +100128299 SOCS5P2 HGNC:HGNC:44598 +100128302 SDHCP2 HGNC:HGNC:45177 +100128305 RPS13P1 HGNC:HGNC:36309 +100128307 PIGCP2 HGNC:HGNC:45149 +100128310 LOC100128310 - +100128312 SLC25A6P6 HGNC:HGNC:43855 +100128317 LOC100128317 Ensembl:ENSG00000233491 +100128318 RPL26P17 HGNC:HGNC:35662 +100128324 EXOGP1 HGNC:HGNC:44547 +100128325 LOC100128325 - +100128327 TRAPPC3L MIM:614137|HGNC:HGNC:21090|Ensembl:ENSG00000173626|Vega:OTTHUMG00000015440 +100128334 LOC100128334 - +100128335 LOC100128335 - +100128337 IPO7P2 HGNC:HGNC:39838 +100128338 FAM83H-AS1 HGNC:HGNC:48720|Ensembl:ENSG00000203499|Vega:OTTHUMG00000165153 +100128339 BCAS2P3 HGNC:HGNC:39596 +100128340 LOC100128340 - +100128341 RBMX2P1 HGNC:HGNC:39923 +100128345 LOC100128345 - +100128347 RPL15P15 HGNC:HGNC:36780 +100128351 RPL21P52 HGNC:HGNC:36621 +100128355 LOC100128355 - +100128358 RPS6P24 HGNC:HGNC:36070 +100128360 LOC100128360 - +100128361 LOC100128361 - +100128362 LOC100128362 - +100128364 LOC100128364 - +100128365 LOC100128365 - +100128368 VN1R21P HGNC:HGNC:37336 +100128372 HMGN2P28 HGNC:HGNC:39395 +100128373 LOC100128373 - +100128377 RPS29P7 HGNC:HGNC:36594 +100128378 LINC00696 HGNC:HGNC:34426 +100128379 LOC100128379 - +100128384 VN1R65P HGNC:HGNC:37385 +100128385 FAM225B HGNC:HGNC:21865|Ensembl:ENSG00000225684 +100128386 LOC100128386 Ensembl:ENSG00000248027 +100128390 CALM2P1 HGNC:HGNC:1446 +100128393 RPL35AP36 HGNC:HGNC:36103 +100128397 NIFKP5 HGNC:HGNC:44953 +100128398 LOC100128398 Ensembl:ENSG00000176593 +100128407 LOC100128407 - +100128408 RPL22P10 HGNC:HGNC:36559 +100128410 NPM1P34 HGNC:HGNC:45213 +100128412 VTA1P2 HGNC:HGNC:50484 +100128413 XIAPP3 HGNC:HGNC:52377 +100128416 RAB28P5 HGNC:HGNC:51547 +100128420 LINC00892 HGNC:HGNC:48578|Ensembl:ENSG00000233093 +100128423 RPS24P14 HGNC:HGNC:35744 +100128427 UBTFL9 HGNC:HGNC:50286 +100128428 LOC100128428 - +100128431 GEMIN8P1 HGNC:HGNC:31818 +100128441 LOC100128441 - +100128442 LOC100128442 - +100128448 UQCRHP4 HGNC:HGNC:38047 +100128449 IL9RP1 HGNC:HGNC:6031 +100128450 RPS6P8 HGNC:HGNC:36999 +100128454 LOC100128454 - +100128456 CCNB1IP1P3 HGNC:HGNC:37695 +100128459 CCNJP1 HGNC:HGNC:22512 +100128462 RPF2P2 HGNC:HGNC:44015 +100128464 LOC100128464 - +100128465 IFIT6P HGNC:HGNC:38020 +100128467 LOC100128467 - +100128469 SNRPCP3 HGNC:HGNC:49818 +100128483 TPT1P2 HGNC:HGNC:49294 +100128493 UBE2V2P1 HGNC:HGNC:44885 +100128494 LOC100128494 Ensembl:ENSG00000251143 +100128496 C20orf78 HGNC:HGNC:16210 +100128497 LOC100128497 - +100128503 DPPA2P2 HGNC:HGNC:44627 +100128505 ASTN2-AS1 HGNC:HGNC:51175|Ensembl:ENSG00000229105 +100128511 NEBL-AS1 HGNC:HGNC:44899|Ensembl:ENSG00000231920 +100128512 FXYD6P2 HGNC:HGNC:4032 +100128514 ARHGAP42P5 HGNC:HGNC:43942 +100128516 ATP5F1P5 HGNC:HGNC:39746 +100128519 RPS24P11 HGNC:HGNC:36050 +100128521 TPT1P14 HGNC:HGNC:49305 +100128523 LOC100128523 - +100128525 UQCRFS1P1 HGNC:HGNC:12588 +100128531 LOC100128531 Ensembl:ENSG00000203280 +100128535 RPS18P14 HGNC:HGNC:36386 +100128536 SETP8 HGNC:HGNC:42927 +100128537 C1orf132 HGNC:HGNC:32018 +100128540 LOC100128540 - +100128541 ATP6V1G1P2 HGNC:HGNC:29359 +100128542 BET1P1 HGNC:HGNC:51363 +100128546 LOC100128546 - +100128548 LOC100128548 - +100128553 CTAGE4 MIM:608910|HGNC:HGNC:24772|Ensembl:ENSG00000225932|Vega:OTTHUMG00000157997 +100128554 LINC02347 HGNC:HGNC:53269|Ensembl:ENSG00000214043 +100128560 MYHAS HGNC:HGNC:50609 +100128568 LOC100128568 Ensembl:ENSG00000266983 +100128569 C19orf71 HGNC:HGNC:34496|Ensembl:ENSG00000183397|Vega:OTTHUMG00000180764 +100128573 LOC100128573 - +100128574 ARMCX3-AS1 HGNC:HGNC:41038 +100128579 CDKN2AIPNLP2 HGNC:HGNC:39855 +100128588 LOC100128588 - +100128589 GAPDHP39 HGNC:HGNC:37796 +100128590 SLC8A1-AS1 HGNC:HGNC:44102|Ensembl:ENSG00000227028 +100128592 LOC100128592 - +100128593 LOC100128593 - +100128594 LOC100128594 - +100128595 HNRNPDLP1 HGNC:HGNC:48752 +100128596 NDUFB9P2 HGNC:HGNC:52270 +100128601 LOC100128601 - +100128603 C1GALT1P2 HGNC:HGNC:51615 +100128605 RPS15AP13 HGNC:HGNC:36774 +100128610 LOC100128610 - +100128617 UBA52P7 HGNC:HGNC:36615 +100128618 SLC25A3P2 HGNC:HGNC:43784 +100128621 CYB5AP2 HGNC:HGNC:2573 +100128622 LOC100128622 - +100128625 SRSF1P1 HGNC:HGNC:39417 +100128626 PPP1R2P10 HGNC:HGNC:42008 +100128627 CDC42P3 HGNC:HGNC:44427 +100128628 RGS17P1 HGNC:HGNC:39729 +100128637 EEF1A1P26 HGNC:HGNC:37899 +100128639 HMGB1P48 HGNC:HGNC:39281 +100128640 ACVR2B-AS1 HGNC:HGNC:44161|Ensembl:ENSG00000229589 +100128646 RPL10AP7 HGNC:HGNC:35601 +100128653 LOC100128653 - +100128655 LOC100128655 - +100128657 CHCHD4P2 HGNC:HGNC:44490 +100128662 RPL27P3 - +100128664 RPL22P20 HGNC:HGNC:36281 +100128665 FYTTD1P1 HGNC:HGNC:38035 +100128673 LOC100128673 - +100128674 LOC100128674 - +100128675 HPN-AS1 HGNC:HGNC:47041|Ensembl:ENSG00000227392 +100128676 LOC100128676 - +100128678 BTBD10P1 HGNC:HGNC:51540 +100128681 CCNG2P1 HGNC:HGNC:50853 +100128682 LINC01531 HGNC:HGNC:51270|Ensembl:ENSG00000205786 +100128685 SLC16A14P1 HGNC:HGNC:43809 +100128686 LOC100128686 - +100128688 GPR50-AS1 HGNC:HGNC:40259|Ensembl:ENSG00000234696 +100128690 ELL2P4 HGNC:HGNC:39346 +100128696 PABPC1P6 HGNC:HGNC:37986 +100128701 HNRNPA1P41 HGNC:HGNC:48770 +100128705 AK4P4 HGNC:HGNC:39067 +100128707 NIFKP4 HGNC:HGNC:44952 +100128710 RPL9P30 HGNC:HGNC:36316 +100128711 NDUFB10P1 HGNC:HGNC:52272 +100128712 PRELID3BP3 HGNC:HGNC:49065 +100128713 LOC100128713 - +100128714 LINC02346 HGNC:HGNC:53268|Ensembl:ENSG00000206187 +100128721 LOC100128721 - +100128723 CBX1P3 HGNC:HGNC:38657 +100128725 APOOP4 HGNC:HGNC:48742 +100128731 OST4 HGNC:HGNC:32483|Ensembl:ENSG00000228474|Vega:OTTHUMG00000151990 +100128733 FCF1P3 HGNC:HGNC:44615 +100128738 LOC100128738 - +100128739 LOC100128739 - +100128745 RPLP1P8 HGNC:HGNC:36104 +100128750 RBPMS-AS1 HGNC:HGNC:48721|Ensembl:ENSG00000254109 +100128756 RPS7P9 HGNC:HGNC:36998 +100128759 LOC100128759 - +100128762 LOC100128762 - +100128764 THAP12P6 HGNC:HGNC:39570 +100128766 RPL8P2 HGNC:HGNC:17220 +100128770 LOC100128770 Ensembl:ENSG00000205890 +100128771 EIF4BP3 HGNC:HGNC:37936 +100128772 LOC100128772 - +100128775 LOC100128775 - +100128776 LOC100128776 - +100128777 KLF8P1 HGNC:HGNC:41520 +100128781 FAM35CP HGNC:HGNC:31427 +100128782 LINC00476 HGNC:HGNC:27858|Ensembl:ENSG00000175611 +100128787 LINC01349 HGNC:HGNC:50568 +100128788 SRRM2-AS1 HGNC:HGNC:44162|Ensembl:ENSG00000205913 +100128790 LYPLA2P3 HGNC:HGNC:50446 +100128800 LOC100128800 - +100128801 DRAXINP1 HGNC:HGNC:44334 +100128803 LOC100128803 - +100128804 AGGF1P8 HGNC:HGNC:51745 +100128807 RPL35AP37 HGNC:HGNC:36426 +100128808 LOC100128808 - +100128811 GPR158-AS1 HGNC:HGNC:44163|Ensembl:ENSG00000233642 +100128817 AK6P2 HGNC:HGNC:51679 +100128818 LPEQ6126 - +100128822 LINC01003 HGNC:HGNC:48957|Ensembl:ENSG00000261455 +100128827 FRG2FP HGNC:HGNC:51366 +100128830 LINC01165 HGNC:HGNC:49534 +100128833 LOC100128833 - +100128834 CLK3P2 HGNC:HGNC:49786 +100128836 HNRNPA1P36 HGNC:HGNC:48765 +100128845 CDC42EP3P1 HGNC:HGNC:49673 +100128849 BNIP3P34 HGNC:HGNC:49714 +100128853 ZNF725P HGNC:HGNC:32461 +100128857 B3GALNT1P1 HGNC:HGNC:51302 +100128863 RPS15AP29 HGNC:HGNC:35981 +100128865 LOC100128865 - +100128867 RBM22P3 HGNC:HGNC:39696 +100128880 RAD1P1 HGNC:HGNC:49479 +100128881 VPS9D1-AS1 HGNC:HGNC:48915|Ensembl:ENSG00000261373 +100128882 LOC100128882 - +100128885 LOC100128885 - +100128888 RPSAP36 HGNC:HGNC:35727 +100128889 NDUFAF4P4 HGNC:HGNC:44543 +100128890 FAM66B HGNC:HGNC:28890|Ensembl:ENSG00000215374 +100128893 GATA6-AS1 HGNC:HGNC:48840|Ensembl:ENSG00000266010 +100128894 NAP1L1P2 HGNC:HGNC:38005 +100128898 LOC100128898 - +100128899 RPL7L1P9 HGNC:HGNC:39491 +100128902 PRDX3P3 HGNC:HGNC:39266 +100128903 NPM1P4 HGNC:HGNC:7924 +100128905 LINC01960 HGNC:HGNC:52785|Ensembl:ENSG00000260868 +100128906 LOC100128906 - +100128908 LOC100128908 - +100128911 PCNPP2 HGNC:HGNC:41974 +100128912 RPS21P4 HGNC:HGNC:35922 +100128923 RPS6P16 HGNC:HGNC:35668 +100128926 LOC100128926 - +100128927 ZBTB42 MIM:613915|HGNC:HGNC:32550|Ensembl:ENSG00000179627|Vega:OTTHUMG00000170790 +100128929 LOC100128929 - +100128930 SDCBPP1 HGNC:HGNC:44684 +100128934 FXYD6P1 HGNC:HGNC:4031 +100128936 RPL10AP6 HGNC:HGNC:36504 +100128939 LOC100128939 - +100128944 YWHAQP3 HGNC:HGNC:37682 +100128946 LINC01310 HGNC:HGNC:50501|Ensembl:ENSG00000205632 +100128948 LOC100128948 - +100128958 LOC100128958 - +100128961 GAPDHP62 HGNC:HGNC:4156 +100128963 RPL3P9 HGNC:HGNC:36839 +100128964 LOC100128964 - +100128966 LOC100128966 - +100128974 RBM17P4 HGNC:HGNC:50369 +100128977 MAPT-AS1 HGNC:HGNC:43738 +100128979 LOC100128979 - +100128982 KATNBL1P4 HGNC:HGNC:49054 +100128983 LOC100128983 - +100128984 RPL35AP7 HGNC:HGNC:36212 +100128985 NPM1P38 HGNC:HGNC:45217 +100128988 LOC100128988 - +100128990 MED6P1 HGNC:HGNC:45164 +100128991 RSL24D1P9 HGNC:HGNC:37880 +100128993 LOC100128993 - +100128998 C20orf181 HGNC:HGNC:16174 +100129001 LOC100129001 - +100129004 RPL3P10 HGNC:HGNC:36819 +100129005 APOOP2 HGNC:HGNC:48740 +100129007 FMO8P HGNC:HGNC:32209 +100129008 CUL4AP1 HGNC:HGNC:44027 +100129009 DCAF13P1 HGNC:HGNC:43866 +100129011 LSM6P1 HGNC:HGNC:31738 +100129013 ACTR3P2 HGNC:HGNC:38676 +100129017 RPL24P5 HGNC:HGNC:36102 +100129023 ARF4P4 HGNC:HGNC:37628 +100129027 LOC100129027 Ensembl:ENSG00000205424 +100129028 RPLP1P4 HGNC:HGNC:36939 +100129029 PKP4-AS1 HGNC:HGNC:52580|Ensembl:ENSG00000204380 +100129031 UBL5P3 HGNC:HGNC:44641 +100129032 GLYATL1P1 HGNC:HGNC:37866 +100129034 LOC100129034 - +100129037 LOC100129037 - +100129040 CCDC11P1 HGNC:HGNC:43919 +100129045 EIF3KP2 HGNC:HGNC:44017 +100129046 LOC100129046 - +100129049 PIGFP3 HGNC:HGNC:45151 +100129050 CICP20 HGNC:HGNC:48830 +100129052 LOC100129052 - +100129053 KDM4F HGNC:HGNC:52413 +100129055 LOC100129055 - +100129060 SEMA3F-AS1 HGNC:HGNC:40518|Ensembl:ENSG00000235016 +100129061 RPL7P25 HGNC:HGNC:36455 +100129066 UNQ6494 Ensembl:ENSG00000237372 +100129067 NPM1P35 HGNC:HGNC:45214 +100129074 THAP12P5 HGNC:HGNC:39569 +100129075 KTN1-AS1 HGNC:HGNC:19842|Ensembl:ENSG00000186615 +100129078 LOC100129078 - +100129080 TDGF1P7 HGNC:HGNC:11707 +100129083 LOC100129083 - +100129085 LOC100129085 - +100129086 HIGD1AP1 HGNC:HGNC:22804 +100129090 RPS5P4 HGNC:HGNC:36122 +100129094 BTNL10 HGNC:HGNC:42540 +100129096 LOC100129096 - +100129098 LOC100129098 - +100129099 LOC100129099 - +100129100 LOC100129100 - +100129102 RPL22P4 HGNC:HGNC:36299 +100129107 TCF3P1 HGNC:HGNC:49742 +100129108 LOC100129108 - +100129118 LOC100129118 - +100129123 ACE3P HGNC:HGNC:44365 +100129124 TVP23BP1 HGNC:HGNC:31127 +100129128 KHDC1L HGNC:HGNC:37274|Ensembl:ENSG00000256980|Vega:OTTHUMG00000132474 +100129129 LOC100129129 - +100129130 LOC100129130 - +100129133 LOC100129133 - +100129135 LOC100129135 - +100129137 LOC100129137 - +100129138 LOC100129138 Ensembl:ENSG00000215869 +100129140 LOC100129140 - +100129141 RPL21P37 HGNC:HGNC:35704 +100129143 SMUG1P1 HGNC:HGNC:49401 +100129144 LOC100129144 - +100129148 LOC100129148 - +100129155 LOC100129155 - +100129156 RBBP6P1 HGNC:HGNC:45108 +100129160 NMNAT1P2 HGNC:HGNC:49164 +100129162 RSL24D1P2 HGNC:HGNC:37867 +100129167 RFESDP1 HGNC:HGNC:39420 +100129168 LOC100129168 - +100129174 POLR2KP2 HGNC:HGNC:42652 +100129175 LOC100129175 Ensembl:ENSG00000224090 +100129176 RPL13P6 HGNC:HGNC:19809 +100129179 RPL9P5 HGNC:HGNC:23557 +100129180 RPL36AP11 HGNC:HGNC:36385 +100129184 LOC100129184 - +100129192 MICC HGNC:HGNC:7092 +100129193 MUPP HGNC:HGNC:49202 +100129195 ZSCAN16-AS1 HGNC:HGNC:48982|Ensembl:ENSG00000269293 +100129196 MATN1-AS1 HGNC:HGNC:40364|Ensembl:ENSG00000186056 +100129199 RPS3AP40 HGNC:HGNC:35869 +100129201 PRR13P3 HGNC:HGNC:50616 +100129202 LOC100129202 - +100129203 LOC100129203 - +100129205 LOC100129205 - +100129213 SLC39A12-AS1 HGNC:HGNC:44881|Ensembl:ENSG00000226083 +100129215 LOC100129215 Ensembl:ENSG00000226180 +100129216 DEFB131B HGNC:HGNC:38058|Ensembl:ENSG00000225805|Vega:OTTHUMG00000167536 +100129223 THCAT155 - +100129224 LOC100129224 - +100129227 RPS6P22 HGNC:HGNC:35655 +100129229 HNRNPCP10 HGNC:HGNC:48821 +100129231 HSPA8P20 HGNC:HGNC:44936 +100129234 RPL27P7 HGNC:HGNC:36107 +100129237 NPM1P21 HGNC:HGNC:13855 +100129239 CXorf51A HGNC:HGNC:30533|Ensembl:ENSG00000224440|Vega:OTTHUMG00000022600 +100129243 RPS15AP12 HGNC:HGNC:36759 +100129245 LOC100129245 - +100129248 PDSS1P1 HGNC:HGNC:49740 +100129250 SMIM27 HGNC:HGNC:31420|Ensembl:ENSG00000235453|Vega:OTTHUMG00000019742 +100129251 FTLP4 HGNC:HGNC:37952 +100129254 LOC100129254 - +100129256 NMNAT1P5 HGNC:HGNC:49167 +100129259 BRD7P5 HGNC:HGNC:37631 +100129260 RPL7L1P1 HGNC:HGNC:39455 +100129262 LOC100129262 - +100129265 LOC100129265 - +100129269 LINC01160 HGNC:HGNC:49525 +100129271 C1orf68 HGNC:HGNC:29468|Ensembl:ENSG00000198854|Vega:OTTHUMG00000012401 +100129272 TOMM20P4 HGNC:HGNC:50522 +100129274 LOC100129274 - +100129276 LOC100129276 - +100129277 TPMTP3 HGNC:HGNC:44566 +100129278 TDRD15 HGNC:HGNC:45037|Ensembl:ENSG00000218819|Vega:OTTHUMG00000151795 +100129279 RPS27P14 HGNC:HGNC:35923 +100129283 LDHBP3 HGNC:HGNC:39136 +100129284 RPS15AP39 HGNC:HGNC:35800 +100129288 MORF4L1P5 HGNC:HGNC:35425 +100129291 LOC100129291 Ensembl:ENSG00000237265 +100129293 LOC100129293 - +100129295 LOC100129295 - +100129297 LOC100129297 - +100129298 TPMTP4 HGNC:HGNC:44567 +100129306 RPS20P32 HGNC:HGNC:36444 +100129307 LOC100129307 - +100129308 DNAJA1P1 HGNC:HGNC:39337 +100129310 RPL31P14 HGNC:HGNC:35477 +100129315 VN1R66P HGNC:HGNC:37386 +100129316 LOC100129316 - +100129319 SLC25A6P5 HGNC:HGNC:43854 +100129320 HMGB3P10 HGNC:HGNC:39302 +100129321 LOC100129321 - +100129325 HNRNPA1P64 HGNC:HGNC:48794 +100129329 SNRPEP3 HGNC:HGNC:43445 +100129331 RAB28P2 HGNC:HGNC:50381 +100129332 RPL29P20 HGNC:HGNC:36682 +100129337 EIF4BP2 HGNC:HGNC:37935 +100129339 TPSP1 HGNC:HGNC:14182 +100129340 LOC100129340 - +100129344 LOC100129344 - +100129345 LINC02291 HGNC:HGNC:53207|Ensembl:ENSG00000197176 +100129347 LINC00484 HGNC:HGNC:27862|Ensembl:ENSG00000229694 +100129348 CDCA4P2 HGNC:HGNC:49771 +100129351 AGGF1P4 HGNC:HGNC:38054 +100129352 LOC100129352 - +100129354 NRADDP HGNC:HGNC:19337 +100129355 BOD1P2 HGNC:HGNC:51436 +100129357 RPL9P29 HGNC:HGNC:35533 +100129358 LOC100129358 - +100129361 SMIM10L1 HGNC:HGNC:49847|Ensembl:ENSG00000256537|Vega:OTTHUMG00000168565 +100129367 LOC100129367 - +100129368 HNRNPH1P2 HGNC:HGNC:48810 +100129370 NDUFB9P3 HGNC:HGNC:52271 +100129374 RPL18P3 HGNC:HGNC:35783 +100129375 LOC100129375 - +100129377 RPL23P9 HGNC:HGNC:36853 +100129379 RPS29P17 HGNC:HGNC:35479 +100129381 LOC100129381 - +100129382 THAP12P4 HGNC:HGNC:39568 +100129384 LOC100129384 - +100129385 C9orf92 HGNC:HGNC:19054|Ensembl:ENSG00000205549|Vega:OTTHUMG00000019588 +100129387 GABPB1-AS1 HGNC:HGNC:44157 +100129391 LOC100129391 - +100129394 RPL12P42 HGNC:HGNC:36165 +100129396 FAM106CP HGNC:HGNC:38396 +100129398 LPGAT1P1 HGNC:HGNC:31402 +100129401 LYPLA1P1 HGNC:HGNC:44005 +100129402 HAUS4P1 HGNC:HGNC:43763 +100129403 EEF1GP4 HGNC:HGNC:44559 +100129404 LOC100129404 - +100129405 MSTO2P HGNC:HGNC:26329 +100129407 FAM236A HGNC:HGNC:44268|Ensembl:ENSG00000275520|Vega:OTTHUMG00000188527 +100129418 RPL31P16 HGNC:HGNC:36001 +100129421 RPL18P2 HGNC:HGNC:35759 +100129422 LOC100129422 - +100129423 EI24P1 HGNC:HGNC:44586 +100129424 RPL19P12 HGNC:HGNC:36047 +100129427 DDC-AS1 HGNC:HGNC:40171|Ensembl:ENSG00000226122 +100129428 RANP5 HGNC:HGNC:39860 +100129434 LOC100129434 - +100129438 ZFRP1 HGNC:HGNC:38030 +100129452 GAMTP2 HGNC:HGNC:37697 +100129454 SNRPEP1 HGNC:HGNC:35244 +100129455 LOC100129455 - +100129456 LOC100129456 - +100129457 LOC100129457 - +100129459 PWWP2AP1 HGNC:HGNC:39709 +100129460 DPY19L1P1 HGNC:HGNC:22395 +100129461 LYRM4-AS1 HGNC:HGNC:52055|Ensembl:ENSG00000272142 +100129464 LINC01546 HGNC:HGNC:27336|Ensembl:ENSG00000228459 +100129468 BOD1P1 HGNC:HGNC:51435 +100129471 LOC100129471 - +100129472 PTP4A1P6 HGNC:HGNC:41933 +100129473 LOC100129473 - +100129476 LOC100129476 - +100129478 LOC100129478 - +100129480 MKRN2OS HGNC:HGNC:40375|Ensembl:ENSG00000225526|Vega:OTTHUMG00000155368 +100129482 ZNF37BP HGNC:HGNC:13103|Ensembl:ENSG00000234420 +100129483 LOC100129483 - +100129484 LOC100129484 Ensembl:ENSG00000234432 +100129487 RPL24P9 - +100129492 LOC100129492 - +100129497 LOC100129497 - +100129503 LOC100129503 Ensembl:ENSG00000280351 +100129507 MAN1A2P1 HGNC:HGNC:50488 +100129512 POU5F1P2 HGNC:HGNC:33309 +100129515 ETDB HGNC:HGNC:44269|Ensembl:ENSG00000224107|Vega:OTTHUMG00000022469 +100129516 LINC02012 HGNC:HGNC:52847|Ensembl:ENSG00000272989 +100129517 RPL26P23 HGNC:HGNC:36634 +100129518 SOD2-OT1 HGNC:HGNC:53445|Ensembl:ENSG00000112096 +100129520 TEX13C HGNC:HGNC:52277|Ensembl:ENSG00000282815|Vega:OTTHUMG00000191426 +100129526 LOC100129526 - +100129527 LOC100129527 - +100129528 MUC8 MIM:601932|HGNC:HGNC:7519 +100129534 LOC100129534 Ensembl:ENSG00000269896 +100129540 LOC100129540 - +100129542 RPS29P21 HGNC:HGNC:36479 +100129543 ZNF730 HGNC:HGNC:32470|Ensembl:ENSG00000183850|Vega:OTTHUMG00000183227 +100129550 LINC02035 HGNC:HGNC:52875|Ensembl:ENSG00000273033 +100129552 RPS26P38 HGNC:HGNC:36406 +100129553 RPL13AP16 HGNC:HGNC:35722 +100129554 LOC100129554 - +100129555 HMGN1P7 HGNC:HGNC:39350 +100129556 RPS10P27 HGNC:HGNC:36850 +100129557 HNRNPA3P8 HGNC:HGNC:48497 +100129561 MYL6P3 HGNC:HGNC:37812 +100129564 PTP4A1P4 HGNC:HGNC:41931 +100129566 SNRPCP2 HGNC:HGNC:49817 +100129570 PEBP1P3 HGNC:HGNC:44345 +100129573 LOC100129573 - +100129574 LOC100129574 - +100129575 MR1P1 - +100129577 LOC100129577 - +100129583 FAM47E HGNC:HGNC:34343|Ensembl:ENSG00000189157|Vega:OTTHUMG00000185390 +100129584 RPL17P44 HGNC:HGNC:36396 +100129586 LOC100129586 - +100129587 VN1R34P HGNC:HGNC:37354 +100129589 LOC100129589 - +100129591 RPL29P24 HGNC:HGNC:35616 +100129594 FAM8A3P HGNC:HGNC:16374 +100129595 PRUNEP1 HGNC:HGNC:39723 +100129597 LINC00462 HGNC:HGNC:42811|Ensembl:ENSG00000233610 +100129599 RPS29P14 HGNC:HGNC:36471 +100129601 LOC100129601 - +100129603 LOC100129603 - +100129604 PABPC1P12 HGNC:HGNC:37994 +100129606 HNRNPA1P73 HGNC:HGNC:48803 +100129607 LOC100129607 - +100129611 PRAMEF31P HGNC:HGNC:51893 +100129616 LOC100129616 - +100129617 LOC100129617 - +100129618 THAP5P2 HGNC:HGNC:44502 +100129620 LOC100129620 Ensembl:ENSG00000232825 +100129622 RSU1P1 HGNC:HGNC:31114 +100129626 LOC100129626 - +100129627 PPP1R1AP2 HGNC:HGNC:16317 +100129629 EIF2S2P6 HGNC:HGNC:37794 +100129631 IGHV2OR16-5 HGNC:HGNC:5579|IMGT/GENE-DB:IGHV2/OR16-5 +100129634 RPL9P19 HGNC:HGNC:36688 +100129636 LOC100129636 - +100129640 DDX55P1 HGNC:HGNC:49852 +100129641 BTG1P1 HGNC:HGNC:37692 +100129643 POM121L11P HGNC:HGNC:35447 +100129645 RPL18P9 HGNC:HGNC:36766 +100129646 LOC100129646 - +100129647 RPL5P35 HGNC:HGNC:36967 +100129649 PGDP2 HGNC:HGNC:39144 +100129650 RPS26P55 HGNC:HGNC:36500 +100129654 TCF24 HGNC:HGNC:32275|Ensembl:ENSG00000261787|Vega:OTTHUMG00000177282 +100129657 RPL17P18 HGNC:HGNC:36538 +100129661 LOC100129661 - +100129662 FGF13-AS1 HGNC:HGNC:44264|Ensembl:ENSG00000226031 +100129664 PRELID3BP1 HGNC:HGNC:49063 +100129667 LOC100129667 - +100129669 IZUMO3 HGNC:HGNC:31421|Ensembl:ENSG00000205442|Vega:OTTHUMG00000019704 +100129670 RPL18P8 HGNC:HGNC:36878 +100129672 LOC100129672 - +100129682 LOC100129682 - +100129683 LOC100129683 - +100129685 RPL21P125 HGNC:HGNC:36039 +100129687 LOC100129687 - +100129690 RAD1P2 HGNC:HGNC:49480 +100129692 EIF4BP9 HGNC:HGNC:37942 +100129693 LOC100129693 - +100129694 R3HDM2P2 HGNC:HGNC:44057 +100129696 TFP1 HGNC:HGNC:11759 +100129697 LOC100129697 - +100129706 HMGB1P13 HGNC:HGNC:13318 +100129707 LOC100129707 - +100129708 IPO7P1 HGNC:HGNC:39837 +100129714 RCC2P8 HGNC:HGNC:42384 +100129716 ARRDC3-AS1 HGNC:HGNC:44145|Ensembl:ENSG00000281357 +100129718 RPS13P3 HGNC:HGNC:36866 +100129722 STPG3-AS1 HGNC:HGNC:51176|Ensembl:ENSG00000275549 +100129723 HMGB1P12 HGNC:HGNC:13317 +100129724 LOC100129724 - +100129725 LOC100129725 - +100129726 LINC01126 HGNC:HGNC:49275|Ensembl:ENSG00000279873 +100129727 TMED10P2 HGNC:HGNC:38105 +100129728 LOC100129728 - +100129731 RAB11AP1 HGNC:HGNC:45188 +100129732 RPS6P15 HGNC:HGNC:36942 +100129734 LOC100129734 - +100129736 CDV3P1 HGNC:HGNC:42387 +100129738 SETP9 HGNC:HGNC:42928 +100129739 DYNLL1P4 HGNC:HGNC:49655 +100129742 RPS3AP13 - +100129743 RPL7P14 HGNC:HGNC:35984 +100129755 RSL24D1P1 HGNC:HGNC:13979 +100129761 AMD1P4 HGNC:HGNC:51609 +100129769 AKR1B1P6 HGNC:HGNC:33498 +100129772 TMPOP1 HGNC:HGNC:21364 +100129774 LOC100129774 - +100129776 LOC100129776 - +100129777 BNIP3P6 HGNC:HGNC:39659 +100129779 LOC100129779 - +100129781 MIR193BHG HGNC:HGNC:51945 +100129782 ATP5A1P4 HGNC:HGNC:23563 +100129784 RPL17P26 HGNC:HGNC:35597 +100129792 CCDC152 HGNC:HGNC:34438|Ensembl:ENSG00000198865|Vega:OTTHUMG00000162141 +100129793 TLK1P1 HGNC:HGNC:28608 +100129794 SLC25A21-AS1 HGNC:HGNC:44298|Ensembl:ENSG00000258708 +100129795 NPM1P50 HGNC:HGNC:45229 +100129796 RPL13P13 HGNC:HGNC:36832 +100129799 RPL13AP21 HGNC:HGNC:35654 +100129800 ZNF807 HGNC:HGNC:33229 +100129801 RPL12P37 HGNC:HGNC:35565 +100129808 RPL24P6 HGNC:HGNC:36637 +100129813 CT45A11P HGNC:HGNC:51336 +100129815 PGAM1P13 HGNC:HGNC:42461 +100129818 LOC100129818 - +100129819 RPL22P7 HGNC:HGNC:35602 +100129824 PIP5K1P2 HGNC:HGNC:38068 +100129827 MRVI1-AS1 HGNC:HGNC:43434|Ensembl:ENSG00000177112 +100129830 LOC100129830 - +100129836 COL4A2-AS2 HGNC:HGNC:39849 +100129842 ZNF737 MIM:603984|HGNC:HGNC:32468|Ensembl:ENSG00000237440|Vega:OTTHUMG00000179732 +100129843 LOC100129843 - +100129844 LOC100129844 - +100129845 PCOLCE-AS1 HGNC:HGNC:40430|Ensembl:ENSG00000224729 +100129847 LOC100129847 - +100129851 LOC100129851 - +100129853 DNAJC19P1 HGNC:HGNC:45064 +100129854 LOC100129854 - +100129856 RPL37AP5 HGNC:HGNC:36977 +100129858 SCOC-AS1 HGNC:HGNC:50601|Ensembl:ENSG00000196951 +100129861 RSL24D1P7 HGNC:HGNC:37877 +100129863 SUCLA2P2 HGNC:HGNC:38102 +100129866 EI24P2 HGNC:HGNC:44587 +100129867 RPL30P14 HGNC:HGNC:36257 +100129869 LOC100129869 - +100129871 GRPEL2P3 HGNC:HGNC:41971 +100129878 LOC100129878 - +100129880 NENFP2 HGNC:HGNC:50299 +100129882 RPL31P49 HGNC:HGNC:35909 +100129902 RPS29P11 HGNC:HGNC:36413 +100129905 RPS27P19 HGNC:HGNC:36094 +100129917 LOC100129917 Ensembl:ENSG00000249592 +100129919 HMGB1P45 HGNC:HGNC:39277 +100129920 HNRNPA1P40 HGNC:HGNC:48769 +100129921 RPL15P4 HGNC:HGNC:21663 +100129923 LOC100129923 - +100129924 TMEM269 HGNC:HGNC:52381|Ensembl:ENSG00000274386|Vega:OTTHUMG00000188150 +100129926 RPL12P13 HGNC:HGNC:51936 +100129928 RPL31P5 HGNC:HGNC:23547 +100129929 NUP210P2 HGNC:HGNC:42707 +100129930 RPL10P10 HGNC:HGNC:35486 +100129931 LOC100129931 Ensembl:ENSG00000245748 +100129933 GLYATL1P2 HGNC:HGNC:37863 +100129934 RPL34P14 HGNC:HGNC:35927 +100129935 LOC100129935 Ensembl:ENSG00000268153 +100129937 KNOP1P1 HGNC:HGNC:48919 +100129939 RPS10P31 HGNC:HGNC:35998 +100129940 LOC100129940 Ensembl:ENSG00000197301 +100129941 RSL24D1P5 HGNC:HGNC:37870 +100129942 LOC100129942 - +100129947 LOC100129947 - +100129948 LOC100129948 - +100129949 LOC100129949 - +100129952 RPL39P10 HGNC:HGNC:35745 +100129955 LOC100129955 - +100129956 LOC100129956 - +100129957 LOC100129957 - +100129958 KRT8P44 HGNC:HGNC:39878 +100129959 AK3P4 HGNC:HGNC:39063 +100129960 SDCBPP2 HGNC:HGNC:44686 +100129961 CCNT2-AS1 HGNC:HGNC:40130 +100129966 LOC100129966 - +100129969 FAM205C HGNC:HGNC:42673|Ensembl:ENSG00000187791|Vega:OTTHUMG00000019841 +100129972 NPM1P47 HGNC:HGNC:45226 +100129973 CERNA1 HGNC:HGNC:52664 +100129975 RPL10P15 HGNC:HGNC:52347 +100129976 BRI3BPP1 HGNC:HGNC:51482 +100129982 RPL12P19 HGNC:HGNC:36248 +100129983 UBE2CP3 HGNC:HGNC:43552 +100129989 LOC100129989 - +100129991 RPL38P2 HGNC:HGNC:36620 +100129994 GRPEL2P2 HGNC:HGNC:41970 +100129995 LINC01460 HGNC:HGNC:50858|Ensembl:ENSG00000205334 +100129996 LOC100129996 - +100129997 LOC100129997 - +100129998 RPL5P27 HGNC:HGNC:36172 +100130001 LOC100130001 - +100130002 HNRNPA1P23 HGNC:HGNC:39541 +100130003 SNRPGP2 HGNC:HGNC:30999 +100130006 EIF4A1P11 HGNC:HGNC:37932 +100130009 HMGA1P8 HGNC:HGNC:39183 +100130011 SYPL1P1 HGNC:HGNC:53546 +100130014 SETP5 HGNC:HGNC:42924 +100130015 URAHP MIM:615805|HGNC:HGNC:43695|Ensembl:ENSG00000222019 +100130017 FTLP10 HGNC:HGNC:37959|Ensembl:ENSG00000250426 +100130018 LOC100130018 - +100130026 LOC100130026 - +100130027 LOC100130027 - +100130029 HMGA1P6 HGNC:HGNC:19121 +100130034 RPL36AP12 HGNC:HGNC:35897 +100130035 LOC100130035 - +100130038 OSBPL9P2 HGNC:HGNC:48732 +100130042 MTHFD2P6 HGNC:HGNC:48864 +100130043 SETP17 HGNC:HGNC:42936 +100130044 LOC100130044 - +100130048 LOC100130048 - +100130049 LOC100130049 - +100130052 LOC100130052 - +100130059 VN1R70P HGNC:HGNC:37391 +100130060 GNPATP HGNC:HGNC:34031 +100130063 LOC100130063 - +100130064 EIF4BP4 HGNC:HGNC:37937 +100130066 RPL9P22 HGNC:HGNC:36994 +100130067 HPRT1P1 HGNC:HGNC:51622 +100130070 RPS27P13 HGNC:HGNC:36203 +100130072 LOC100130072 - +100130073 IQSEC3P2 HGNC:HGNC:49849 +100130074 KRT17P8 HGNC:HGNC:50726 +100130075 LOC100130075 - +100130079 RFPL4AP6 HGNC:HGNC:45142 +100130083 HBCBP - +100130086 HSFX2 HGNC:HGNC:32701|Ensembl:ENSG00000268738|Vega:OTTHUMG00000188526 +100130088 LOC100130088 - +100130090 SFR1P1 HGNC:HGNC:51531 +100130097 KIF28P HGNC:HGNC:49205 +100130099 MIPEPP2 HGNC:HGNC:39457 +100130102 LOC100130102 - +100130105 TRIM51CP HGNC:HGNC:43968 +100130106 RPS23P7 HGNC:HGNC:43899 +100130108 ZNF849P HGNC:HGNC:34389 +100130109 SNRPEP4 HGNC:HGNC:43446 +100130110 ZSWIM5P1 HGNC:HGNC:43768 +100130111 LOC100130111 Ensembl:ENSG00000256802 +100130114 LOC100130114 - +100130117 DDX6P2 HGNC:HGNC:37806 +100130119 LAMTOR3P1 HGNC:HGNC:39726 +100130121 LOC100130121 - +100130134 LOC100130134 - +100130137 LOC100130137 - +100130139 UBE2D3P2 HGNC:HGNC:39010 +100130148 MAPT-IT1 HGNC:HGNC:43741|Ensembl:ENSG00000279685 +100130155 MIR124-2HG HGNC:HGNC:48723|Ensembl:ENSG00000254377 +100130158 KNOP1P5 HGNC:HGNC:48923 +100130167 NUS1P4 HGNC:HGNC:38474 +100130170 LOC100130170 - +100130171 LOC100130171 - +100130172 LOC100130172 - +100130176 LOC100130176 - +100130177 LOC100130177 - +100130178 LSM3P4 HGNC:HGNC:44349 +100130180 LOC100130180 - +100130183 RPS24P19 HGNC:HGNC:35683 +100130187 TUBB3P2 HGNC:HGNC:42181 +100130190 SRRM1P3 HGNC:HGNC:38164 +100130192 RPS12P31 HGNC:HGNC:35578 +100130196 HNRNPCP9 HGNC:HGNC:48820 +100130197 EFCAB14-AS1 HGNC:HGNC:44108|Ensembl:ENSG00000228237 +100130203 LOC100130203 - +100130204 NIPA2P2 HGNC:HGNC:42042 +100130207 LOC100130207 - +100130209 LOC100130209 - +100130210 LOC100130210 - +100130211 EEF1A1P29 HGNC:HGNC:37904 +100130225 RPL13P11 HGNC:HGNC:35805 +100130231 LINC00861 HGNC:HGNC:45133|Ensembl:ENSG00000245164 +100130233 NPM1P8 HGNC:HGNC:7928 +100130234 EEF1A1P27 HGNC:HGNC:37900 +100130235 KATNBL1P2 HGNC:HGNC:49052 +100130238 LOC100130238 - +100130239 UBA52P6 HGNC:HGNC:36763 +100130240 RPS5P2 HGNC:HGNC:17222 +100130247 COX6CP3 HGNC:HGNC:31721 +100130249 PP2672 - +100130251 NXNP1 HGNC:HGNC:50561 +100130253 RCBTB2P1 HGNC:HGNC:45167 +100130256 LOC100130256 - +100130259 SALL4P2 HGNC:HGNC:39819 +100130260 EEF1GP2 HGNC:HGNC:44557 +100130264 LOC100130264 Ensembl:ENSG00000179447 +100130265 ARL2BPP4 HGNC:HGNC:39448 +100130268 LOC100130268 - +100130270 LOC100130270 - +100130274 CCDC166 HGNC:HGNC:41910|Ensembl:ENSG00000255181|Vega:OTTHUMG00000165148 +100130275 TFAP2A-AS1 HGNC:HGNC:40579 +100130277 CDC27P2 HGNC:HGNC:38092 +100130279 HMGB1P44 HGNC:HGNC:39275 +100130283 LOC100130283 - +100130286 RPL34P11 HGNC:HGNC:36412 +100130289 SNRPGP10 HGNC:HGNC:39329 +100130298 LOC100130298 - +100130299 LOC100130299 - +100130300 RPS27AP13 HGNC:HGNC:36667 +100130301 C8orf89 HGNC:HGNC:51258|Ensembl:ENSG00000274443|Vega:OTTHUMG00000189250 +100130302 SUPT20HL1 HGNC:HGNC:30773 +100130307 SPDYE19P HGNC:HGNC:51515 +100130310 MSANTD2P1 HGNC:HGNC:39637 +100130311 C17orf107 HGNC:HGNC:37238|Ensembl:ENSG00000205710|Vega:OTTHUMG00000164838 +100130313 RPS6P23 HGNC:HGNC:39581 +100130316 LOC100130316 - +100130319 TAF9BP2 HGNC:HGNC:38836 +100130321 LOC100130321 - +100130326 LOC100130326 - +100130327 NDUFA5P5 HGNC:HGNC:48847 +100130329 LOC100130329 - +100130331 LOC100130331 Ensembl:ENSG00000237250 +100130335 NAP1L1P3 HGNC:HGNC:38007 +100130338 PABPC1P9 HGNC:HGNC:37991 +100130342 SCGB2B3P HGNC:HGNC:31895 +100130345 LOC100130345 - +100130347 RPS6P5 HGNC:HGNC:36242 +100130348 TMEM262 HGNC:HGNC:49389|Ensembl:ENSG00000187066|Vega:OTTHUMG00000165598 +100130353 LOC100130353 - +100130357 LOC100130357 Vega:OTTHUMG00000014271 +100130359 MED28P4 HGNC:HGNC:45081 +100130361 CXorf49 HGNC:HGNC:30891|Ensembl:ENSG00000215115|Vega:OTTHUMG00000022702 +100130368 SNRPGP4 HGNC:HGNC:39323 +100130370 LOC100130370 - +100130373 LOC100130373 - +100130374 RPL13P14 HGNC:HGNC:36387 +100130376 MTRF1LP2 HGNC:HGNC:50612 +100130383 HIGD1AP12 HGNC:HGNC:43007 +100130384 CENPUP1 HGNC:HGNC:49889 +100130386 LINC00552 HGNC:HGNC:43692|Ensembl:ENSG00000279770 +100130388 EEF1E1P1 HGNC:HGNC:51459 +100130391 YWHAQP5 HGNC:HGNC:37684 +100130392 RPL9P20 HGNC:HGNC:36996 +100130394 LOC100130394 - +100130396 ATP5LP4 HGNC:HGNC:38165 +100130400 RPL21P92 HGNC:HGNC:35606 +100130402 B3GALNT2P1 HGNC:HGNC:51315 +100130403 LOC100130403 - +100130405 HMGB3P26 HGNC:HGNC:39318 +100130409 BTF3P15 HGNC:HGNC:38567 +100130417 LOC100130417 Ensembl:ENSG00000223764 +100130418 CECR7 HGNC:HGNC:1845|Ensembl:ENSG00000237438 +100130435 RPS7P13 HGNC:HGNC:35756 +100130437 LOC100130437 - +100130446 RPS27AP12 HGNC:HGNC:35732 +100130447 RPL12P16 HGNC:HGNC:36926 +100130448 MRS2P1 HGNC:HGNC:20590 +100130449 PP14571 Ensembl:ENSG00000218416 +100130450 RPL3P5 HGNC:HGNC:36934 +100130451 LOC100130451 - +100130452 LOC100130452 - +100130455 LOC100130455 - +100130459 LOC100130459 - +100130460 CAND1.11 - +100130461 CBX1P4 HGNC:HGNC:38658 +100130462 HNF4GP1 HGNC:HGNC:35417 +100130466 NUCKS1P1 HGNC:HGNC:51943 +100130476 LOC100130476 Ensembl:ENSG00000237499 +100130480 LINC01387 HGNC:HGNC:44660|Ensembl:ENSG00000265944 +100130481 CCT6P4 HGNC:HGNC:35148 +100130484 UBFD1P1 HGNC:HGNC:42389 +100130485 LOC100130485 - +100130487 LOC100130487 - +100130488 LOC100130488 - +100130490 TPRG1LP1 HGNC:HGNC:52353 +100130495 RPS12P26 HGNC:HGNC:36320 +100130497 LOC100130497 - +100130500 LOC100130500 - +100130514 PGAM1P1 HGNC:HGNC:42448 +100130519 TMEM221 HGNC:HGNC:21943|Ensembl:ENSG00000188051|Vega:OTTHUMG00000182858 +100130520 CD300H MIM:616560 +100130522 PARD6G-AS1 HGNC:HGNC:44109|Ensembl:ENSG00000267270 +100130523 RPL5P8 HGNC:HGNC:36290 +100130524 RPL6P23 - +100130528 SUCLG2P4 HGNC:HGNC:43999 +100130531 LOC100130531 - +100130532 LOC100130532 - +100130535 VIM2P HGNC:HGNC:43891 +100130537 RPL31P26 HGNC:HGNC:36063 +100130539 C10orf142 HGNC:HGNC:51236|Ensembl:ENSG00000277288|Vega:OTTHUMG00000189253 +100130548 LOC100130548 Ensembl:ENSG00000235138 +100130549 ISCA1P6 HGNC:HGNC:38027 +100130550 LOC100130550 - +100130555 RPL23AP68 HGNC:HGNC:35489 +100130557 NFYC-AS1 HGNC:HGNC:49451 +100130561 HMGB1P10 HGNC:HGNC:4994 +100130562 RPS2P5 HGNC:HGNC:31386 +100130564 SEPT7P7 HGNC:HGNC:38043 +100130566 EIF1P4 HGNC:HGNC:49617 +100130571 LOC100130571 - +100130572 RAD23BP2 HGNC:HGNC:44510 +100130574 LOC100130574 - +100130579 PHBP20 HGNC:HGNC:51553 +100130581 LINC00910 HGNC:HGNC:44361|Ensembl:ENSG00000188825 +100130582 LOC100130582 - +100130584 CLIC4P2 HGNC:HGNC:49798 +100130587 LOC100130587 Ensembl:ENSG00000203900 +100130600 CICP14 HGNC:HGNC:38542 +100130602 LOC100130602 - +100130603 RBM22P13 HGNC:HGNC:49208 +100130606 NPM1P51 HGNC:HGNC:45230 +100130607 LOC100130607 - +100130612 LOC100130612 - +100130613 PRR32 HGNC:HGNC:34498|Ensembl:ENSG00000183631|Vega:OTTHUMG00000022355 +100130618 LOC100130618 - +100130620 LOC100130620 - +100130621 RANP4 HGNC:HGNC:39859 +100130624 RPL15P22 HGNC:HGNC:36933 +100130626 ELOCP18 HGNC:HGNC:38154 +100130630 RPL23P3 HGNC:HGNC:35988 +100130631 EEF1B2P4 HGNC:HGNC:32475 +100130632 LOC100130632 - +100130636 SPATA31D2P HGNC:HGNC:38607 +100130637 MORF4L1P7 HGNC:HGNC:39259 +100130639 LOC100130639 - +100130640 YWHAZP7 HGNC:HGNC:39028 +100130649 LOC100130649 - +100130660 HNRNPA1P45 HGNC:HGNC:48775 +100130664 LOC100130664 - +100130671 IFNWP9 HGNC:HGNC:5455 +100130673 LOC100130673 - +100130674 LOC100130674 - +100130676 RPSAP38 HGNC:HGNC:35963 +100130677 NFYAP1 HGNC:HGNC:34078 +100130680 LOC100130680 - +100130682 LOC100130682 - +100130683 LOC100130683 - +100130684 LOC100130684 - +100130687 FABP5P6 HGNC:HGNC:31069 +100130691 LOC100130691 Ensembl:ENSG00000213963 +100130693 ARHGAP42P2 HGNC:HGNC:43939 +100130698 LOC100130698 - +100130699 RSL24D1P10 HGNC:HGNC:37875 +100130700 TP53TG3HP HGNC:HGNC:51819 +100130701 LOC100130701 - +100130704 LOC100130704 - +100130705 LOC100130705 Ensembl:ENSG00000272899|Vega:OTTHUMG00000158367 +100130708 ANP32BP2 HGNC:HGNC:38552 +100130714 LOC100130714 - +100130717 HDHD5-AS1 HGNC:HGNC:1842|Ensembl:ENSG00000185837 +100130718 RPL34P26 HGNC:HGNC:36100 +100130719 UQCRBP2 HGNC:HGNC:12584 +100130721 RSL24D1P3 HGNC:HGNC:37883 +100130724 LOC100130724 - +100130731 LOC100130731 - +100130733 LRRC70 HGNC:HGNC:35155|Ensembl:ENSG00000186105|Vega:OTTHUMG00000154401 +100130742 LRRC69 HGNC:HGNC:34303|Ensembl:ENSG00000214954|Vega:OTTHUMG00000164023 +100130744 LOC100130744 - +100130746 LOC100130746 - +100130747 LOC100130747 - +100130748 LOC100130748 - +100130750 RPS8P9 HGNC:HGNC:35524 +100130756 UQCRHP1 HGNC:HGNC:31341 +100130758 METTL15P1 HGNC:HGNC:31926 +100130760 LOC100130760 - +100130766 LOC100130766 - +100130771 EFCAB10 HGNC:HGNC:34531|Ensembl:ENSG00000185055|Vega:OTTHUMG00000157397 +100130775 RPS27P23 HGNC:HGNC:35716 +100130776 AGAP2-AS1 HGNC:HGNC:48633|Ensembl:ENSG00000255737 +100130778 LOC100130778 - +100130782 RPS15AP15 HGNC:HGNC:35640 +100130783 LOC100130783 - +100130785 SALL4P5 HGNC:HGNC:39822 +100130786 RPS3AP22 HGNC:HGNC:36573 +100130792 RPL29P27 HGNC:HGNC:35551 +100130794 NDUFS5P7 HGNC:HGNC:44045 +100130799 SRSF10P1 HGNC:HGNC:31002 +100130801 LOC100130801 - +100130802 RPL39P13 HGNC:HGNC:36705 +100130803 UBL5P1 HGNC:HGNC:44639 +100130820 CCNG1P1 HGNC:HGNC:39177 +100130821 OSBPL9P1 HGNC:HGNC:48731 +100130823 RPS17P9 HGNC:HGNC:36160 +100130827 SBK3 HGNC:HGNC:44121|Ensembl:ENSG00000231274|Vega:OTTHUMG00000155831 +100130841 LOC100130841 - +100130842 LOC100130842 - +100130843 SPRYD7P1 HGNC:HGNC:52300 +100130848 TSPY20P HGNC:HGNC:38093 +100130849 LOC100130849 Ensembl:ENSG00000233437 +100130854 LOC100130854 - +100130855 USP3-AS1 HGNC:HGNC:44140|Ensembl:ENSG00000259248 +100130861 LOC100130861 - +100130866 IFNWP15 HGNC:HGNC:5449 +100130871 ARMC8P1 HGNC:HGNC:49918 +100130872 LOC100130872 - +100130873 CARM1P1 HGNC:HGNC:23392 +100130876 LOC100130876 - +100130879 ZNRF2P3 HGNC:HGNC:45113 +100130880 LOC100130880 - +100130881 LOC100130881 - +100130887 ATE1-AS1 HGNC:HGNC:49496|Ensembl:ENSG00000226864 +100130889 PSORS1C3 HGNC:HGNC:17203|Ensembl:ENSG00000204528 +100130890 TSTD3 HGNC:HGNC:40910|Ensembl:ENSG00000228439|Vega:OTTHUMG00000015265 +100130891 LOC100130891 - +100130892 RPL7P32 HGNC:HGNC:35692 +100130894 VAC14-AS1 HGNC:HGNC:48605|Ensembl:ENSG00000214353 +100130898 FLYWCH1P1 HGNC:HGNC:38033 +100130899 LOC100130899 - +100130909 LOC100130909 - +100130922 RPL22P22 HGNC:HGNC:36109 +100130923 PSMA2P1 HGNC:HGNC:43832 +100130929 RPL5P33 HGNC:HGNC:36703 +100130932 SNRPGP15 HGNC:HGNC:49371 +100130933 SMIM6 HGNC:HGNC:40032|Ensembl:ENSG00000259120|Vega:OTTHUMG00000179796 +100130934 ZNF663P HGNC:HGNC:25342 +100130935 CSAG4 HGNC:HGNC:20923|Ensembl:ENSG00000242599 +100130936 ADI1P1 HGNC:HGNC:52339 +100130950 LOC100130950 Ensembl:ENSG00000261879 +100130954 LINC01502 HGNC:HGNC:51183|Ensembl:ENSG00000237339 +100130958 SYCE1L HGNC:HGNC:37236|Ensembl:ENSG00000205078|Vega:OTTHUMG00000176809 +100130962 ATP5G1P7 HGNC:HGNC:39510 +100130963 RPL38P4 HGNC:HGNC:48867 +100130964 LOC100130964 - +100130967 C6orf99 HGNC:HGNC:21179 +100130968 RPL7L1P4 HGNC:HGNC:39486 +100130970 CTBP2P2 HGNC:HGNC:45194 +100130972 PPP1R2P6 HGNC:HGNC:16321 +100130980 RPS2P35 HGNC:HGNC:36757 +100130983 RPL26P28 HGNC:HGNC:35776 +100130987 LOC100130987 - +100130988 C7orf72 HGNC:HGNC:22564|Ensembl:ENSG00000164500|Vega:OTTHUMG00000155883 +100130990 LOC100130990 - +100130992 LOC100130992 - +100130994 UQCRFS1P3 HGNC:HGNC:39173 +100130995 ZNF969P HGNC:HGNC:44211 +100130996 YPEL5P1 HGNC:HGNC:50555 +100131011 LOC100131011 - +100131012 YBX1P4 HGNC:HGNC:42425 +100131013 LOC100131013 - +100131017 ZNF316 HGNC:HGNC:13843|Ensembl:ENSG00000205903|Vega:OTTHUMG00000151854 +100131020 RPL9P23 HGNC:HGNC:36807 +100131027 SLC25A5P4 HGNC:HGNC:35471 +100131029 LOC100131029 - +100131031 ANKRD18EP HGNC:HGNC:43609 +100131033 PPIGP1 HGNC:HGNC:34231 +100131036 HMGB3P28 HGNC:HGNC:39320 +100131038 LOC100131038 - +100131041 LOC100131041 - +100131046 SALL4P3 HGNC:HGNC:39820 +100131047 LOC100131047 - +100131051 MED28P3 HGNC:HGNC:45080 +100131055 RPS4XP15 HGNC:HGNC:36308 +100131060 LINC01135 HGNC:HGNC:49450|Ensembl:ENSG00000234807 +100131065 VN1R38P HGNC:HGNC:37358 +100131067 CKMT2-AS1 HGNC:HGNC:48997|Ensembl:ENSG00000247572 +100131068 ERVI-1 HGNC:HGNC:39052 +100131069 LOC100131069 - +100131072 LOC100131072 - +100131078 LOC100131078 - +100131080 LOC100131080 - +100131083 RPS8P5 HGNC:HGNC:36417 +100131084 DNM1P17 HGNC:HGNC:21134 +100131085 RPL7P12 HGNC:HGNC:36611 +100131087 RPLP1P11 HGNC:HGNC:36196 +100131089 SRP14-AS1 HGNC:HGNC:48619|Ensembl:ENSG00000248508 +100131092 ISCA1P3 HGNC:HGNC:38024 +100131094 DPP9-AS1 HGNC:HGNC:50706 +100131096 TNRC6C-AS1 HGNC:HGNC:44360|Ensembl:ENSG00000204282 +100131103 TATDN2P1 HGNC:HGNC:39254 +100131107 LOC100131107 - +100131114 LOC100131114 - +100131117 ZBTB20-AS1 HGNC:HGNC:40640|Ensembl:ENSG00000241560 +100131118 VN1R67P HGNC:HGNC:37387 +100131124 LOC100131124 - +100131126 LOC100131126 - +100131127 LOC100131127 - +100131130 HNRNPA1P13 HGNC:HGNC:39131 +100131135 MTHFD2P4 HGNC:HGNC:48862 +100131137 BSPH1 MIM:612213|HGNC:HGNC:33906|Ensembl:ENSG00000188334|Vega:OTTHUMG00000183137 +100131138 LINC01405 HGNC:HGNC:50688|Ensembl:ENSG00000185847 +100131141 VN1R95P HGNC:HGNC:37415 +100131143 RPL23AP19 HGNC:HGNC:36708 +100131146 LOC100131146 - +100131151 RPLP0P8 HGNC:HGNC:35867 +100131158 LOC100131158 - +100131159 LOC100131159 - +100131160 RPL39P20 HGNC:HGNC:36366 +100131161 RPSAP39 HGNC:HGNC:37040 +100131173 RPS29P12 HGNC:HGNC:36458 +100131176 WDR86-AS1 HGNC:HGNC:41186|Ensembl:ENSG00000243836 +100131183 HMGN2P30 HGNC:HGNC:39397 +100131187 TSTD1 MIM:616041|HGNC:HGNC:35410|Ensembl:ENSG00000215845|Vega:OTTHUMG00000031476 +100131188 LIPT1P1 HGNC:HGNC:39278 +100131189 SSR1P2 HGNC:HGNC:39274 +100131193 CCDC183-AS1 HGNC:HGNC:44105|Ensembl:ENSG00000228544 +100131196 RPS25P8 HGNC:HGNC:36075 +100131200 LOC100131200 - +100131205 RPL21P28 HGNC:HGNC:36258|Ensembl:ENSG00000220749 +100131206 RPL29P16 HGNC:HGNC:36898 +100131207 DNAJA1P2 HGNC:HGNC:39338 +100131208 SNAP25-AS1 HGNC:HGNC:44312|Ensembl:ENSG00000227906 +100131211 NEMP2 MIM:616497|HGNC:HGNC:33700|Ensembl:ENSG00000189362|Vega:OTTHUMG00000154454 +100131213 ZNF503-AS2 HGNC:HGNC:23525|Ensembl:ENSG00000237149 +100131216 LOC100131216 - +100131223 LOC100131223 - +100131229 RPL6P17 HGNC:HGNC:36914 +100131230 RPL30P4 HGNC:HGNC:35871 +100131233 LOC100131233 - +100131234 MIR181A1HG HGNC:HGNC:48659 +100131236 PCBP2P3 HGNC:HGNC:39032 +100131241 LOC100131241 - +100131244 ANKRD63 HGNC:HGNC:40027|Ensembl:ENSG00000230778|Vega:OTTHUMG00000176892 +100131246 RPL9P27 HGNC:HGNC:37012 +100131250 SPCS2P1 HGNC:HGNC:31885 +100131252 FAM213AP2 HGNC:HGNC:52408 +100131254 LOC100131254 - +100131257 LOC100131257 - +100131261 PNRC2P1 HGNC:HGNC:51933 +100131264 LOC100131264 - +100131268 TPT1P1 HGNC:HGNC:16742 +100131279 C2orf69P3 HGNC:HGNC:51802 +100131280 LOC100131280 - +100131281 GLUD1P9 HGNC:HGNC:37696 +100131284 LOC100131284 - +100131286 RPS19P5 HGNC:HGNC:35850 +100131289 LOC100131289 - +100131291 ACTG1P21 HGNC:HGNC:51501 +100131294 LOC100131294 - +100131302 PTCD2P1 HGNC:HGNC:31718 +100131303 LOC100131303 Ensembl:ENSG00000263201|Vega:OTTHUMG00000177460 +100131306 BNIP3P21 HGNC:HGNC:49701 +100131309 THAP12P9 HGNC:HGNC:39573 +100131315 LOC100131315 Ensembl:ENSG00000259721 +100131320 RAB6C-AS1 HGNC:HGNC:49278|Ensembl:ENSG00000225449 +100131327 UQCRC2P1 HGNC:HGNC:44309 +100131328 FAM210CP HGNC:HGNC:44938 +100131333 RPL18P6 HGNC:HGNC:35528 +100131338 RPL15P13 HGNC:HGNC:35915 +100131339 RPL32P4 HGNC:HGNC:10337 +100131340 LOC100131340 - +100131347 LOC100131347 Ensembl:ENSG00000263818 +100131348 LOC100131348 - +100131358 RPL3P12 HGNC:HGNC:36298 +100131360 LOC100131360 - +100131366 LINC00605 HGNC:HGNC:43928|Ensembl:ENSG00000251533 +100131369 DUX4L27 HGNC:HGNC:50808 +100131370 DDX18P6 HGNC:HGNC:31126 +100131372 LOC100131372 - +100131374 PABPC1P5 HGNC:HGNC:37985 +100131378 C11orf91 HGNC:HGNC:34444|Ensembl:ENSG00000205177|Vega:OTTHUMG00000166320 +100131379 RPL36AP1 HGNC:HGNC:23548 +100131387 RPL39P32 HGNC:HGNC:36959 +100131388 NDUFA3P1 HGNC:HGNC:45043 +100131390 SP9 HGNC:HGNC:30690|Ensembl:ENSG00000217236|Vega:OTTHUMG00000150371 +100131393 UBQLN4P2 HGNC:HGNC:38662 +100131395 LOC100131395 - +100131396 RPS6P14 HGNC:HGNC:36738 +100131411 LOC100131411 - +100131415 OR7E163P HGNC:HGNC:45040 +100131418 RPS27P22 HGNC:HGNC:36090 +100131425 LOC100131425 - +100131429 LOC100131429 - +100131434 LINC00893 HGNC:HGNC:44265|Ensembl:ENSG00000241769 +100131439 CD300LD MIM:616301|HGNC:HGNC:16848|Ensembl:ENSG00000204345|Vega:OTTHUMG00000067614 +100131440 CDC42P4 HGNC:HGNC:44428 +100131441 LOC100131441 - +100131442 RCC2P5 HGNC:HGNC:42381 +100131448 LOC100131448 - +100131451 TLR12P HGNC:HGNC:31754 +100131454 DBIL5P HGNC:HGNC:38519|Ensembl:ENSG00000231784 +100131457 SLC25A1P1 HGNC:HGNC:43845 +100131465 LOC100131465 - +100131467 RPS6P9 HGNC:HGNC:35938 +100131469 RPSAP62 HGNC:HGNC:35583 +100131471 LOC100131471 - +100131472 LOC100131472 - +100131478 NPM1P33 HGNC:HGNC:45212 +100131479 LOC100131479 - +100131481 RPL21P38 HGNC:HGNC:36349 +100131482 LOC100131482 - +100131493 ZIK1P1 HGNC:HGNC:38031 +100131495 LOC100131495 - +100131496 LOC100131496 Ensembl:ENSG00000267882 +100131520 LOC100131520 - +100131526 RPL26P6 HGNC:HGNC:34023 +100131527 RPL19P7 HGNC:HGNC:36088 +100131528 APOOP3 HGNC:HGNC:48741 +100131529 LOC100131529 - +100131532 LOC100131532 - +100131533 LOC100131533 - +100131535 RPL5P28 HGNC:HGNC:36827 +100131536 LOC100131536 - +100131539 ZNF705E HGNC:HGNC:33203|Ensembl:ENSG00000214534 +100131546 ECEL1P1 HGNC:HGNC:14017 +100131548 RPS6P4 HGNC:HGNC:36548 +100131550 CNN2P12 HGNC:HGNC:39834 +100131551 LINC00887 HGNC:HGNC:48574|Ensembl:ENSG00000214145 +100131553 LOC100131553 - +100131556 LOC100131556 - +100131557 LOC100131557 - +100131561 FKSG29 - +100131562 LOC100131562 - +100131564 CCDC18-AS1 HGNC:HGNC:52262 +100131565 EIF4EP5 HGNC:HGNC:51463 +100131568 RBM43P1 HGNC:HGNC:46024 +100131572 RPS27P9 HGNC:HGNC:36964 +100131577 BMS1P19 HGNC:HGNC:49163 +100131593 LOC100131593 - +100131597 LOC100131597 - +100131604 LOC100131604 - +100131608 PRR23D1 HGNC:HGNC:49420|Ensembl:ENSG00000255251|Vega:OTTHUMG00000165386 +100131609 HNRNPA1P2 HGNC:HGNC:13958 +100131611 PGAM4P2 HGNC:HGNC:42466 +100131614 RPS4XP22 HGNC:HGNC:36125 +100131616 CASP3P1 HGNC:HGNC:43596 +100131617 LOC100131617 - +100131623 NUTF2P6 HGNC:HGNC:50455 +100131624 WASF1P1 HGNC:HGNC:51533 +100131625 LOC100131625 - +100131626 LOC100131626 - +100131629 ARL2BPP7 HGNC:HGNC:39451 +100131635 LOC100131635 Ensembl:ENSG00000228804 +100131638 CCT4P2 HGNC:HGNC:35141 +100131641 RBM22P12 HGNC:HGNC:49207 +100131655 LOC100131655 Ensembl:ENSG00000264278 +100131656 SDCBPP3 HGNC:HGNC:44687 +100131661 FTLP5 HGNC:HGNC:37953 +100131671 SEC13P1 HGNC:HGNC:44529 +100131672 RPL21P87 HGNC:HGNC:36411 +100131676 LOC100131676 - +100131678 CCNB3P1 HGNC:HGNC:50851 +100131680 LOC100131680 - +100131685 LOC100131685 - +100131688 VN1R68P HGNC:HGNC:37389 +100131689 LOC100131689 - +100131691 MZF1-AS1 HGNC:HGNC:51271|Ensembl:ENSG00000267858 +100131693 EIF4EP2 HGNC:HGNC:32428 +100131695 RNF11P1 HGNC:HGNC:33988 +100131711 RFC3P1 HGNC:HGNC:44531 +100131713 RPL29P11 HGNC:HGNC:36905 +100131725 LOC100131725 - +100131726 FAM83A-AS1 HGNC:HGNC:48658|Ensembl:ENSG00000204949 +100131730 RPL37AP7 HGNC:HGNC:35888 +100131733 USP30-AS1 HGNC:HGNC:40909 +100131736 LOC100131736 - +100131740 CIR1P1 HGNC:HGNC:44011 +100131743 GAPDHP40 HGNC:HGNC:37797 +100131747 LOC100131747 - +100131755 ARMCX4 HGNC:HGNC:28615|Ensembl:ENSG00000196440|Vega:OTTHUMG00000022030 +100131759 RPL19P3 HGNC:HGNC:36671 +100131760 GXYLT1P5 HGNC:HGNC:50424 +100131761 RPS12P12 HGNC:HGNC:36235 +100131770 LOC100131770 - +100131775 PSMA2P2 HGNC:HGNC:43833 +100131777 DPPA2P4 HGNC:HGNC:44629 +100131779 LOC100131779 - +100131784 ARL2BPP8 HGNC:HGNC:39452 +100131785 LOC100131785 - +100131787 RPS27P7 HGNC:HGNC:35622 +100131788 RPL26P29 HGNC:HGNC:36135 +100131789 VN1R46P HGNC:HGNC:37366 +100131796 DACOR1 HGNC:HGNC:51902 +100131797 RPL15P19 - +100131800 UBE2D3P4 HGNC:HGNC:39391 +100131801 PET100 MIM:614770|HGNC:HGNC:40038|Ensembl:ENSG00000229833|Vega:OTTHUMG00000182394 +100131805 RPL6P18 HGNC:HGNC:36911 +100131810 ADH5P3 HGNC:HGNC:22991 +100131814 LINC00271 HGNC:HGNC:32526|Ensembl:ENSG00000231028 +100131816 UBE2DNL HGNC:HGNC:28656|Ensembl:ENSG00000229547 +100131823 SUMO2P7 HGNC:HGNC:39017 +100131825 CADM3-AS1 HGNC:HGNC:40812 +100131827 ZNF717 HGNC:HGNC:29448|Ensembl:ENSG00000227124|Vega:OTTHUMG00000158965 +100131828 CIR1P2 HGNC:HGNC:44012 +100131832 LOC100131832 - +100131842 HNRNPCP8 HGNC:HGNC:48819 +100131846 RPL23AP83 HGNC:HGNC:35846 +100131849 LOC100131849 - +100131852 LOC100131852 - +100131855 C2orf27AP2 HGNC:HGNC:49813 +100131859 LOC100131859 - +100131863 RPS18P5 HGNC:HGNC:36287 +100131866 RPS2P9 HGNC:HGNC:36704 +100131868 LOC100131868 - +100131874 CFL1P3 HGNC:HGNC:1879 +100131877 LOC100131877 - +100131879 ZYG11AP1 HGNC:HGNC:38032 +100131881 EI24P3 HGNC:HGNC:44588 +100131884 LOC100131884 - +100131890 LOC100131890 - +100131893 RPL3P11 HGNC:HGNC:35521 +100131897 FAM196B HGNC:HGNC:37271|Ensembl:ENSG00000204767|Vega:OTTHUMG00000163083 +100131899 E2F4P1 HGNC:HGNC:38684 +100131902 KRTAP25-1 HGNC:HGNC:34003|Ensembl:ENSG00000232263|Vega:OTTHUMG00000125482 +100131905 RPS27P21 HGNC:HGNC:35826 +100131913 RPL5P20 HGNC:HGNC:36660 +100131918 LOC100131918 - +100131921 SERF1AP1 HGNC:HGNC:44061 +100131924 BLOC1S2P1 HGNC:HGNC:51427 +100131932 RCC2P3 HGNC:HGNC:42379 +100131934 LETM1P2 HGNC:HGNC:33985 +100131935 GAPDHP41 HGNC:HGNC:37798 +100131939 LOC100131939 - +100131940 SNX5P1 HGNC:HGNC:41512 +100131943 LOC100131943 - +100131945 RPL35AP13 HGNC:HGNC:35916 +100131947 PRPF38AP2 HGNC:HGNC:44693 +100131950 LOC100131950 - +100131953 ACTG1P22 HGNC:HGNC:51502 +100131956 RPS3P5 HGNC:HGNC:36869 +100131958 RPL15P12 HGNC:HGNC:35529 +100131961 ST13P19 HGNC:HGNC:38862 +100131962 LOC100131962 - +100131964 RPL7L1P3 HGNC:HGNC:39485 +100131971 RPS26P54 HGNC:HGNC:36868 +100131977 LOC100131977 - +100131980 ZNF705G HGNC:HGNC:37134|Ensembl:ENSG00000215372|Vega:OTTHUMG00000165384 +100131981 UBE2V1P9 HGNC:HGNC:44894 +100131983 HNRNPA1P25 HGNC:HGNC:39543 +100131984 ANKRD57P1 HGNC:HGNC:37984 +100131991 RPL29P8 HGNC:HGNC:37026 +100131995 UQCRHP3 HGNC:HGNC:38046 +100131997 FAM27E3 HGNC:HGNC:28655|Ensembl:ENSG00000274026 +100131998 RRN3P3 HGNC:HGNC:37620 +100132004 LOC100132004 - +100132009 LOC100132009 - +100132015 TEX13D HGNC:HGNC:52278 +100132031 DNM1P28 HGNC:HGNC:35175 +100132036 NDUFB4P2 HGNC:HGNC:45250 +100132037 RPS29P10 HGNC:HGNC:37006 +100132039 LOC100132039 - +100132047 RPL22P6 HGNC:HGNC:36473 +100132049 RPS19P4 HGNC:HGNC:35778 +100132053 RPL30P8 HGNC:HGNC:36058 +100132056 DHFRP5 HGNC:HGNC:52355 +100132057 LOC100132057 - +100132058 GPS2P2 HGNC:HGNC:49623 +100132061 RPL9P14 HGNC:HGNC:36816 +100132062 LOC100132062 - +100132066 ALG1L3P HGNC:HGNC:44372 +100132070 FAM231EP HGNC:HGNC:49507 +100132073 CCNB2P1 HGNC:HGNC:50850 +100132074 FOXO6 MIM:611457|HGNC:HGNC:24814 +100132076 LOC100132076 - +100132077 LOC100132077 Ensembl:ENSG00000232063 +100132078 LOC100132078 Ensembl:ENSG00000255428 +100132079 KARSP3 HGNC:HGNC:39209 +100132081 LOC100132081 - +100132086 AK6P1 HGNC:HGNC:51678 +100132090 LOC100132090 - +100132100 DNM1P32 HGNC:HGNC:35179 +100132101 HERC2P7 HGNC:HGNC:4875 +100132103 FAM66E HGNC:HGNC:18735|Ensembl:ENSG00000225725 +100132104 AK4P2 HGNC:HGNC:39066 +100132108 LOC100132108 - +100132111 LOC100132111 - +100132115 RBM22P11 HGNC:HGNC:39704 +100132116 ACTA2-AS1 HGNC:HGNC:45169|Ensembl:ENSG00000180139 +100132121 ETF1P3 HGNC:HGNC:3480 +100132122 RPL35AP5 HGNC:HGNC:35570 +100132124 TSPY17P HGNC:HGNC:37713 +100132126 LOC100132126 - +100132127 RPL39P14 HGNC:HGNC:36609 +100132132 DSTNP5 HGNC:HGNC:44549 +100132142 RPS3AP4 HGNC:HGNC:23562 +100132146 FAM240A HGNC:HGNC:52390|Ensembl:ENSG00000283473|Vega:OTTHUMG00000191662 +100132147 LINC01783 HGNC:HGNC:52573|Ensembl:ENSG00000233421 +100132153 TUBB2BP1 HGNC:HGNC:42332 +100132154 LOC100132154 - +100132159 CALML3-AS1 HGNC:HGNC:44682 +100132163 PHKA2-AS1 HGNC:HGNC:44110 +100132166 IL9RP4 HGNC:HGNC:6034 +100132169 WASIR2 HGNC:HGNC:38609|Ensembl:ENSG00000231439 +100132172 LOC100132172 - +100132173 PPP1R26P3 HGNC:HGNC:42017 +100132174 LINC01987 HGNC:HGNC:52819|Ensembl:ENSG00000267790 +100132179 LOC100132179 - +100132195 TRIM60P13 HGNC:HGNC:38485 +100132199 RPL36AP44 HGNC:HGNC:36986 +100132201 ZSWIM5P2 HGNC:HGNC:43769 +100132202 LOC100132202 - +100132204 DNM1P29 HGNC:HGNC:35176 +100132215 LOC100132215 Ensembl:ENSG00000231609 +100132223 LOC100132223 - +100132229 LOC100132229 - +100132230 FAM201CP HGNC:HGNC:37996 +100132234 LINC00543 HGNC:HGNC:43678|Ensembl:ENSG00000260704 +100132239 LOC100132239 - +100132242 LOC100132242 - +100132247 NPIPB5 HGNC:HGNC:37233|Ensembl:ENSG00000243716|Vega:OTTHUMG00000163573 +100132249 LOC100132249 - +100132251 ABHD17AP9 HGNC:HGNC:38510 +100132260 CDYLP1 HGNC:HGNC:52805 +100132264 RNFT1P2 HGNC:HGNC:44388 +100132265 RPL32P15 HGNC:HGNC:36119 +100132268 FKBP4P6 HGNC:HGNC:50375 +100132273 NDUFA6-AS1 HGNC:HGNC:45273|Ensembl:ENSG00000237037 +100132280 LOC100132280 - +100132285 KIR2DS2 MIM:604953|HGNC:HGNC:6334 +100132286 NDUFB8P3 HGNC:HGNC:33979 +100132287 LOC100132287 - +100132288 TEKT4P2 HGNC:HGNC:40046|Ensembl:ENSG00000188681 +100132289 ABCB10P4 HGNC:HGNC:31130 +100132291 RPS27P29 HGNC:HGNC:36516 +100132295 PPP1R26P4 HGNC:HGNC:42018 +100132304 FAM236B HGNC:HGNC:52640|Ensembl:ENSG00000268994|Vega:OTTHUMG00000188221 +100132306 FAM91A4P HGNC:HGNC:51524 +100132308 SLC29A4P2 HGNC:HGNC:43782 +100132310 FCF1P11 HGNC:HGNC:44623 +100132311 RPL38P3 HGNC:HGNC:35980 +100132321 NIPA2P1 HGNC:HGNC:42041 +100132322 SAR1AP4 HGNC:HGNC:37638 +100132330 LOC100132330 - +100132332 CNOT7P2 HGNC:HGNC:44249 +100132340 CYP4F59P HGNC:HGNC:39947 +100132341 CLUHP3 HGNC:HGNC:28447|Ensembl:ENSG00000131797 +100132346 HSPE1P7 HGNC:HGNC:49327 +100132352 FRG1HP HGNC:HGNC:51767 +100132354 LINC01512 HGNC:HGNC:51201 +100132355 SLC25A1P4 HGNC:HGNC:43848 +100132356 LOC100132356 - +100132358 EEF1A1P34 HGNC:HGNC:37912 +100132372 RPS10P28 HGNC:HGNC:35511 +100132376 RPS29P8 HGNC:HGNC:36915 +100132380 AGGF1P1 HGNC:HGNC:38051 +100132382 RPS14P4 HGNC:HGNC:36419 +100132386 KRTAP4-9 HGNC:HGNC:18910|Ensembl:ENSG00000212722|Vega:OTTHUMG00000133584 +100132396 ZNF705B HGNC:HGNC:32284|Ensembl:ENSG00000215356|Vega:OTTHUMG00000165401 +100132399 GAGE12D MIM:300728|HGNC:HGNC:31904|Ensembl:ENSG00000227488|Vega:OTTHUMG00000024145 +100132400 RPS15AP28 HGNC:HGNC:36381 +100132402 PGGT1BP2 HGNC:HGNC:45112 +100132403 FAM157B HGNC:HGNC:34080 +100132406 NBPF10 MIM:614000|HGNC:HGNC:31992|Ensembl:ENSG00000271425|Vega:OTTHUMG00000013757 +100132413 GKN3P HGNC:HGNC:37701 +100132415 SOCS5P4 HGNC:HGNC:44600 +100132417 FCGR1CP MIM:601503|HGNC:HGNC:3615|Ensembl:ENSG00000265531 +100132420 ANKRD36P1 HGNC:HGNC:37759 +100132421 DUX4L18 HGNC:HGNC:37716 +100132441 GXYLT1P4 HGNC:HGNC:50423 +100132450 IQSEC3P1 HGNC:HGNC:49848 +100132456 GUSBP7 HGNC:HGNC:42321 +100132463 CLDN24 HGNC:HGNC:37200|Ensembl:ENSG00000185758|Vega:OTTHUMG00000160628 +100132464 FAM99B HGNC:HGNC:32369|Ensembl:ENSG00000205865 +100132467 RNF2P1 HGNC:HGNC:33987 +100132476 KRTAP4-7 HGNC:HGNC:18898|Ensembl:ENSG00000240871|Vega:OTTHUMG00000133582 +100132479 RPL22P5 HGNC:HGNC:37022 +100132487 PTCD2P2 HGNC:HGNC:45168 +100132488 RPS27P6 HGNC:HGNC:36163 +100132496 RPS24P9 HGNC:HGNC:35711 +100132498 LOC100132498 - +100132499 RPS29P16 HGNC:HGNC:35560 +100132501 LINC01415 HGNC:HGNC:50709 +100132504 TSPY19P HGNC:HGNC:37998 +100132509 ZNF114P1 HGNC:HGNC:23771 +100132510 GLRXP3 HGNC:HGNC:34049 +100132520 MTRF1LP1 HGNC:HGNC:50611 +100132524 LOC100132524 - +100132526 FGD5P1 HGNC:HGNC:44498|Ensembl:ENSG00000275340 +100132529 TAT-AS1 HGNC:HGNC:51369|Ensembl:ENSG00000260886 +100132534 PDHA1P1 HGNC:HGNC:44636 +100132537 DOCK11P1 HGNC:HGNC:31719 +100132541 GXYLT1P3 HGNC:HGNC:50422 +100132543 LOC100132543 - +100132547 RPL26P33 HGNC:HGNC:36755 +100132562 YPEL5P2 HGNC:HGNC:50556 +100132565 GOLGA8F HGNC:HGNC:32378|Ensembl:ENSG00000153684 +100132570 LOC100132570 - +100132571 LOC100132571 - +100132580 RBMXP4 HGNC:HGNC:34028 +100132591 SERBP1P4 HGNC:HGNC:44631 +100132594 PGAM1P5 HGNC:HGNC:42452|Ensembl:ENSG00000257150 +100132596 XGY2 HGNC:HGNC:34022 +100132597 EIF3EP2 HGNC:HGNC:37919 +100132598 ZNF965P HGNC:HGNC:42025 +100132599 LOC100132599 - +100132601 GAPDHP68 HGNC:HGNC:4146 +100132606 AGGF1P7 HGNC:HGNC:51740 +100132609 LOC100132609 - +100132612 LINC02312 HGNC:HGNC:53231 +100132615 LOC100132615 - +100132617 SNX18P23 HGNC:HGNC:39631 +100132618 ZRANB2-AS1 HGNC:HGNC:43594 +100132619 ATP5A1P10 HGNC:HGNC:37668 +100132621 LOC100132621 - +100132626 LOC100132626 - +100132630 CICP3 HGNC:HGNC:37742 +100132641 BTF3P14 HGNC:HGNC:38571 +100132644 LOC100132644 - +100132645 RPL17P41 HGNC:HGNC:36292 +100132647 LOC100132647 - +100132651 LOC100132651 - +100132656 FKBP4P1 HGNC:HGNC:44038 +100132658 LOC100132658 - +100132659 LOC100132659 - +100132669 LOC100132669 - +100132672 GXYLT1P6 HGNC:HGNC:50425 +100132673 RPS2P28 HGNC:HGNC:35780 +100132677 BSN-AS2 HGNC:HGNC:42445|Ensembl:ENSG00000226913 +100132678 RPL7AP45 HGNC:HGNC:35935 +100132681 NFU1P1 HGNC:HGNC:44553 +100132683 PDCL3P3 HGNC:HGNC:44504 +100132686 LOC100132686 Ensembl:ENSG00000268472 +100132698 LOC100132698 - +100132699 NFU1P2 HGNC:HGNC:44554 +100132707 PAXIP1-AS2 HGNC:HGNC:48958|Ensembl:ENSG00000214106 +100132708 CYP4F30P HGNC:HGNC:25270|Ensembl:ENSG00000214081 +100132712 NAMPTP2 HGNC:HGNC:51314 +100132722 RPL15P21 HGNC:HGNC:36190 +100132723 LOC100132723 - +100132724 DCAF13P3 HGNC:HGNC:43868 +100132733 ANKRD20A13P HGNC:HGNC:43604 +100132735 LOC100132735 - +100132736 LOC100132736 - +100132741 LOC100132741 - +100132742 RPL17P7 HGNC:HGNC:36005 +100132753 RFKP2 HGNC:HGNC:39182 +100132759 VN1R7P HGNC:HGNC:8496 +100132762 LOC100132762 - +100132766 PABPC1P8 HGNC:HGNC:37988 +100132772 RAB28P3 HGNC:HGNC:50382 +100132773 LOC100132773 - +100132774 KDM4A-AS1 HGNC:HGNC:40528 +100132778 NACAP6 HGNC:HGNC:49493 +100132781 LOC100132781 - +100132789 LOC100132789 - +100132795 RPL12P32 HGNC:HGNC:36597 +100132796 NIFKP6 HGNC:HGNC:44954 +100132797 LOC100132797 - +100132803 HNRNPH1P1 HGNC:HGNC:48751 +100132808 RBMX2P2 HGNC:HGNC:39924 +100132812 LOC100132812 - +100132813 LOC100132813 Vega:OTTHUMG00000165635 +100132815 IPO5P1 HGNC:HGNC:49687 +100132817 LOC100132817 - +100132824 LOC100132824 - +100132830 LOC100132830 - +100132831 LOC100132831 - +100132832 PMS2P9 HGNC:HGNC:9135 +100132834 LOC100132834 - +100132841 NMNAT1P4 HGNC:HGNC:49166 +100132849 LOC100132849 - +100132857 LOC100132857 - +100132863 HMGB1P37 HGNC:HGNC:39184 +100132865 LOC100132865 - +100132871 RAB28P4 HGNC:HGNC:51548 +100132874 LOC100132874 - +100132891 MSC-AS1 HGNC:HGNC:48724|Ensembl:ENSG00000235531 +100132906 RPL13AP10 HGNC:HGNC:36864 +100132911 DPH3P1 HGNC:HGNC:16136 +100132916 FAM159B HGNC:HGNC:34236|Ensembl:ENSG00000145642|Vega:OTTHUMG00000162292 +100132917 RAP1BP3 HGNC:HGNC:49782 +100132918 EIF4EP3 HGNC:HGNC:51461 +100132920 CICP4 HGNC:HGNC:37753 +100132922 RPL6P11 - +100132923 FAM66D HGNC:HGNC:24159 +100132924 RPL13AP19 HGNC:HGNC:35855 +100132929 FAM25BP HGNC:HGNC:23584 +100132932 FAM197Y9 HGNC:HGNC:37477 +100132938 AQP7P4 HGNC:HGNC:32056 +100132940 PRELID3BP6 HGNC:HGNC:49068 +100132948 FAM27C HGNC:HGNC:23668|Ensembl:ENSG00000154537 +100132949 RBM17P3 HGNC:HGNC:50368 +100132961 RPS21P2 HGNC:HGNC:36191 +100132963 SMIM9 HGNC:HGNC:41915|Ensembl:ENSG00000203870|Vega:OTTHUMG00000024243 +100132965 GYG1P1 HGNC:HGNC:39712 +100132967 FAM223A HGNC:HGNC:30612|Ensembl:ENSG00000279245 +100132972 SYPL1P2 HGNC:HGNC:53547 +100132973 ELOCP29 HGNC:HGNC:49170 +100132977 LOC100132977 - +100132978 ATP6V0CP1 HGNC:HGNC:31323 +100132979 GOLGA8DP HGNC:HGNC:32376|Ensembl:ENSG00000175676 +100132987 LINC00856 HGNC:HGNC:45111|Ensembl:ENSG00000230417 +100132988 RPL37AP3 HGNC:HGNC:36222 +100132992 HMGN1P30 HGNC:HGNC:39374 +100132993 RPS21P3 HGNC:HGNC:36847 +100132994 CXorf49B HGNC:HGNC:34229|Ensembl:ENSG00000215113|Vega:OTTHUMG00000021804 +100132995 RPS8P3 HGNC:HGNC:31000 +100133005 RASA4DP HGNC:HGNC:44226 +100133007 LOC100133007 - +100133012 CHEK2P1 HGNC:HGNC:37999 +100133024 AMD1P1 HGNC:HGNC:44898 +100133029 LOC100133029 - +100133036 FAM95B1 HGNC:HGNC:32318|Ensembl:ENSG00000223839 +100133037 RPL7P4 HGNC:HGNC:21634 +100133038 RPL18AP7 HGNC:HGNC:35607 +100133040 PPP1R26P5 HGNC:HGNC:42019 +100133044 BCRP8 HGNC:HGNC:39076 +100133050 LOC100133050 - +100133053 CXorf51B HGNC:HGNC:42787|Ensembl:ENSG00000235699|Vega:OTTHUMG00000022599 +100133054 RPS9P3 HGNC:HGNC:36635 +100133059 LOC100133059 - +100133062 FAM217AP1 HGNC:HGNC:49613 +100133064 PPP1R26P2 HGNC:HGNC:42016 +100133073 LOC100133073 - +100133074 SLC25A5P9 HGNC:HGNC:35468 +100133077 LOC100133077 Ensembl:ENSG00000203987 +100133079 SLC25A1P2 HGNC:HGNC:43847 +100133087 VN1R18P HGNC:HGNC:37334 +100133091 LOC100133091 Ensembl:ENSG00000205485 +100133092 LOC100133092 - +100133093 FAM25G HGNC:HGNC:23590|Ensembl:ENSG00000189090|Vega:OTTHUMG00000018117 +100133100 RPL6P8 HGNC:HGNC:37044 +100133102 LOC100133102 - +100133103 RPL7L1P13 HGNC:HGNC:44212 +100133108 RPL13P10 HGNC:HGNC:35943 +100133121 FAM27B HGNC:HGNC:23667 +100133122 RBPJP7 HGNC:HGNC:37487 +100133123 LINC01203 HGNC:HGNC:49634|Ensembl:ENSG00000226985 +100133127 LOC100133127 - +100133128 DEFB108F HGNC:HGNC:38062 +100133137 LOC100133137 - +100133139 RPL12P41 HGNC:HGNC:35999 +100133147 LOC100133147 - +100133150 LOC100133150 - +100133161 LINC01001 HGNC:HGNC:38540 +100133162 RPL32P34 HGNC:HGNC:35903 +100133163 BCRP7 HGNC:HGNC:39075 +100133165 LOC100133165 - +100133168 CCR12P HGNC:HGNC:39812 +100133170 RPL11P1 HGNC:HGNC:37021 +100133172 FAM66A HGNC:HGNC:30444 +100133177 LOC100133177 - +100133180 DDX3P1 HGNC:HGNC:42171 +100133190 ADIRF-AS1 HGNC:HGNC:45127 +100133193 RPL32P28 HGNC:HGNC:36328 +100133203 RAB28P1 HGNC:HGNC:50380 +100133204 C9orf147 HGNC:HGNC:31438 +100133205 LINC00240 HGNC:HGNC:18772|Ensembl:ENSG00000224843 +100133206 RBM22P5 HGNC:HGNC:39698 +100133210 COX6B1P7 HGNC:HGNC:37677 +100133211 LOC100133211 - +100133212 ABHD17AP7 HGNC:HGNC:38508 +100133220 GOLGA6L3 HGNC:HGNC:37441 +100133222 RPL39P27 HGNC:HGNC:36114 +100133225 LOC100133225 - +100133234 SBF1P1 HGNC:HGNC:31098|Ensembl:ENSG00000248522 +100133235 RPL26P14 HGNC:HGNC:36184 +100133244 LOC100133244 - +100133251 PRR23D2 HGNC:HGNC:49396|Ensembl:ENSG00000255378|Vega:OTTHUMG00000165398 +100133252 LOC100133252 - +100133255 RPS14P5 HGNC:HGNC:36087 +100133259 CBX1P5 HGNC:HGNC:21006 +100133261 LOC100133261 - +100133262 ATP6V0E1P3 HGNC:HGNC:41937 +100133265 BMS1P7 HGNC:HGNC:23655 +100133267 DEFB130B HGNC:HGNC:39814|Ensembl:ENSG00000233050|Vega:OTTHUMG00000158721 +100133268 HAUS6P2 HGNC:HGNC:43765 +100133273 RPL21P80 HGNC:HGNC:35697 +100133284 LOC100133284 - +100133285 PCDH8P1 HGNC:HGNC:39937 +100133286 LOC100133286 Ensembl:ENSG00000230212 +100133294 RPL34P16 HGNC:HGNC:37033 +100133301 FAM231B HGNC:HGNC:49506|Ensembl:ENSG00000268991|Vega:OTTHUMG00000189241 +100133307 CYP1D1P HGNC:HGNC:39968 +100133308 RSU1P2 HGNC:HGNC:44391 +100133309 EIF4A2P3 HGNC:HGNC:45100 +100133310 HMGB1P28 HGNC:HGNC:39119 +100133311 HOXA-AS3 HGNC:HGNC:43748|Ensembl:ENSG00000254369 +100133314 SETP1 HGNC:HGNC:19279 +100133315 LOC100133315 - +100133316 LOC100133316 - +100133319 PRO1804 Ensembl:ENSG00000278873 +100133321 KLF17P1 HGNC:HGNC:41521 +100133326 LOC100133326 - +100133330 RBM17P1 HGNC:HGNC:50366 +100133331 LOC100133331 - +100133461 LINC02171 HGNC:HGNC:53033|Ensembl:ENSG00000250632 +100133545 MRPL23-AS1 HGNC:HGNC:42812|Ensembl:ENSG00000226416 +100133612 LINC01134 HGNC:HGNC:49449|Ensembl:ENSG00000236423 +100133668 RPS27P24 HGNC:HGNC:37005 +100133669 LOC100133669 - +100133791 ERV18-1 HGNC:HGNC:41524 +100133920 LOC100133920 Ensembl:ENSG00000261522 +100133941 CD24 MIM:600074|HGNC:HGNC:1645|Ensembl:ENSG00000272398|Vega:OTTHUMG00000188439 +100133957 UXT-AS1 HGNC:HGNC:49239|Ensembl:ENSG00000267064 +100133985 LINC01816 HGNC:HGNC:52621|Ensembl:ENSG00000231327 +100133991 MAP3K14-AS1 HGNC:HGNC:44359|Ensembl:ENSG00000267278 +100134015 UBOX5-AS1 HGNC:HGNC:44111|Ensembl:ENSG00000235958 +100134040 LOC100134040 MIM:615171 +100134229 JHDM1D-AS1 HGNC:HGNC:48959|Ensembl:ENSG00000260231 +100134259 LINC01119 HGNC:HGNC:49262|Ensembl:ENSG00000239332 +100134317 LOC100134317 - +100134362 LOC100134362 - +100134368 LOC100134368 Ensembl:ENSG00000236829 +100134391 LOC100134391 - +100134423 LOC100134423 - +100134444 KCNJ18 MIM:613236|HGNC:HGNC:39080|Ensembl:ENSG00000260458|Vega:OTTHUMG00000175863 +100134507 LOC100134507 - +100134713 NDUFB2-AS1 HGNC:HGNC:40396|Ensembl:ENSG00000240889 +100134822 LOC100134822 - +100134868 LOC100134868 - +100134869 UBE2Q2P2 HGNC:HGNC:37440 +100134934 TEN1 MIM:613130|HGNC:HGNC:37242|Ensembl:ENSG00000257949|Ensembl:ENSG00000261408|Vega:OTTHUMG00000132686|Vega:OTTHUMG00000170136 +100134938 UPK3BL1 HGNC:HGNC:37278|Ensembl:ENSG00000267368|Vega:OTTHUMG00000165036 +100135063 GTF3AP6 HGNC:HGNC:49749 +100135064 GTF3AP1 HGNC:HGNC:49744 +100135756 ATG3P1 HGNC:HGNC:31123 +100137047 JMJD7 HGNC:HGNC:34397|Ensembl:ENSG00000243789|Vega:OTTHUMG00000156810 +100137049 PLA2G4B MIM:606088|HGNC:HGNC:9036|Ensembl:ENSG00000243708|Vega:OTTHUMG00000156809 +100141515 C17orf99 HGNC:HGNC:34490|Ensembl:ENSG00000187997|Vega:OTTHUMG00000153871 +100142659 CTAGE8 HGNC:HGNC:37294|Ensembl:ENSG00000244693|Vega:OTTHUMG00000158009 +100144434 ETL4 MIM:611631 +100144435 VTRNA3-1P HGNC:HGNC:23027 +100144494 KDELC1P1 HGNC:HGNC:39193 +100144595 LOC100144595 - +100144596 LINC00029 HGNC:HGNC:16184 +100144597 LINC01056 HGNC:HGNC:49050|Ensembl:ENSG00000237119 +100144602 EPHA5-AS1 HGNC:HGNC:50602|Ensembl:ENSG00000250846 +100144603 CHKB-AS1 HGNC:HGNC:40146|Ensembl:ENSG00000205559 +100144604 LINC00930 HGNC:HGNC:48620|Ensembl:ENSG00000258647 +100144631 PPP6CP HGNC:HGNC:34077 +100144632 HPBP - +100144748 KLLN MIM:612105|HGNC:HGNC:37212|Ensembl:ENSG00000227268|Vega:OTTHUMG00000186455 +100147744 RNU7-1 HGNC:HGNC:34033|Ensembl:ENSG00000238923 +100147745 RNU7-2P HGNC:HGNC:34098 +100147746 RNU7-3P HGNC:HGNC:34099 +100147747 RNU7-4P HGNC:HGNC:34100 +100147748 RNU7-5P HGNC:HGNC:34101 +100147749 RNU7-6P HGNC:HGNC:34102 +100147750 RNU5B-2P HGNC:HGNC:34182 +100147751 RNU5B-3P HGNC:HGNC:34183 +100147752 RNU5B-4P HGNC:HGNC:34184 +100147753 RNU5B-5P HGNC:HGNC:34185 +100147754 RNU5B-6P HGNC:HGNC:34186 +100147755 RNU7-7P HGNC:HGNC:34103 +100147756 RNU7-8P HGNC:HGNC:34104 +100147757 RNU7-9P HGNC:HGNC:34105 +100147758 RNU7-10P HGNC:HGNC:34106 +100147759 RNU7-11P HGNC:HGNC:34107 +100147760 RNU7-12P HGNC:HGNC:34108 +100147761 RNU7-13P HGNC:HGNC:34109 +100147762 RNU7-14P HGNC:HGNC:34110 +100147763 RNU7-15P HGNC:HGNC:34111 +100147764 RNU7-16P HGNC:HGNC:34112 +100147765 RNU7-17P HGNC:HGNC:34113 +100147766 RNU7-18P HGNC:HGNC:34114 +100147767 RNU7-19P HGNC:HGNC:34115 +100147768 RNU7-20P HGNC:HGNC:34116 +100147769 RNU7-21P HGNC:HGNC:34117 +100147770 RNU7-22P HGNC:HGNC:34118 +100147771 RNU7-23P HGNC:HGNC:34119 +100147773 LOC100147773 - +100147811 CBX1P2 HGNC:HGNC:38656 +100147812 RNU7-25P HGNC:HGNC:34121 +100147813 RNU7-26P HGNC:HGNC:34122 +100147814 RNU7-27P HGNC:HGNC:34123 +100147815 RNU7-28P HGNC:HGNC:34124 +100147816 RNU7-29P HGNC:HGNC:34125 +100147817 RNU7-30P HGNC:HGNC:34126 +100147818 RNU7-31P HGNC:HGNC:34127 +100147819 RNU7-32P HGNC:HGNC:34128 +100147820 RNU7-33P HGNC:HGNC:34129 +100147821 RNU7-34P HGNC:HGNC:34130 +100147822 RNU7-35P HGNC:HGNC:34131 +100147823 RNU7-36P HGNC:HGNC:34132 +100147824 RNU7-37P HGNC:HGNC:34133 +100147825 RNU7-38P HGNC:HGNC:34134 +100147826 RNU7-39P HGNC:HGNC:34135 +100147827 RNU7-40P HGNC:HGNC:34136 +100147828 RNU7-41P HGNC:HGNC:34137 +100147829 RNU7-42P HGNC:HGNC:34138 +100147830 RNU7-43P HGNC:HGNC:34139 +100147831 RNU7-44P HGNC:HGNC:34140 +100147832 RNU7-45P HGNC:HGNC:34141 +100147833 RNU7-46P HGNC:HGNC:34142 +100147834 RNU7-47P HGNC:HGNC:34143 +100147835 RNU7-48P HGNC:HGNC:34144 +100147836 RNU7-49P HGNC:HGNC:34145 +100147837 RNU7-50P HGNC:HGNC:34146 +100151640 EXOSC3P1 HGNC:HGNC:33989 +100151641 PHKG1P4 HGNC:HGNC:33918 +100151642 ATG12P1 HGNC:HGNC:21466 +100151643 KRTAP20-4 HGNC:HGNC:34002|Ensembl:ENSG00000206105|Vega:OTTHUMG00000125519 +100151644 OTSC8 MIM:612096|HGNC:HGNC:32939 +100151645 USF1P1 HGNC:HGNC:23773 +100151646 LETM1P3 HGNC:HGNC:33986 +100151647 RNU7-51P HGNC:HGNC:34147 +100151648 RNU7-52P HGNC:HGNC:34148 +100151649 RNU7-53P HGNC:HGNC:34149 +100151650 RNU7-54P HGNC:HGNC:34150 +100151651 RNU7-56P HGNC:HGNC:34152 +100151652 RNU7-57P HGNC:HGNC:34153 +100151653 RNU7-58P HGNC:HGNC:34154 +100151654 RNU7-59P HGNC:HGNC:34155 +100151655 RNU7-60P HGNC:HGNC:34156 +100151656 RNU7-61P HGNC:HGNC:34157 +100151657 RNU7-62P HGNC:HGNC:34158 +100151658 RNU7-63P HGNC:HGNC:34159 +100151661 CBX5P1 HGNC:HGNC:38659 +100151662 RNU7-64P HGNC:HGNC:34160 +100151663 RNU7-65P HGNC:HGNC:34161 +100151664 RNU7-66P HGNC:HGNC:34162 +100151665 RNU7-67P HGNC:HGNC:34163 +100151666 RNU7-69P HGNC:HGNC:34165 +100151667 RNU7-70P HGNC:HGNC:34166 +100151668 RNU7-71P HGNC:HGNC:34167 +100151669 RNU7-72P HGNC:HGNC:34168 +100151670 RNU7-73P HGNC:HGNC:34169 +100151671 RNU7-74P HGNC:HGNC:34170 +100151672 RNU7-75P HGNC:HGNC:34171 +100151673 RNU7-76P HGNC:HGNC:34172 +100151674 RNU7-77P HGNC:HGNC:34173 +100151675 RNU7-78P HGNC:HGNC:34174 +100151676 RNU7-79P HGNC:HGNC:34175 +100151677 RNU7-80P HGNC:HGNC:34176 +100151678 RNU7-81P HGNC:HGNC:34177 +100151679 RNU7-82P HGNC:HGNC:34178 +100151680 RNU7-83P HGNC:HGNC:34179 +100151681 RNU7-84P HGNC:HGNC:34180 +100151682 RNU7-85P HGNC:HGNC:34181 +100151683 RNU4ATAC MIM:601428|HGNC:HGNC:34016|Ensembl:ENSG00000264229 +100151684 RNU6ATAC MIM:601429|HGNC:HGNC:34017|Ensembl:ENSG00000221676 +100151685 RNU6ATAC2P HGNC:HGNC:34092 +100151686 RNU6ATAC3P HGNC:HGNC:34093 +100151687 RNU6ATAC4P HGNC:HGNC:34094 +100151688 RNU6ATAC5P HGNC:HGNC:34095 +100158257 NF1P7 HGNC:HGNC:34230 +100158258 NEK2P3 HGNC:HGNC:37817 +100158262 SCARNA9L HGNC:HGNC:33559 +100169750 PRINS HGNC:HGNC:34235 +100169751 RNA5S1 HGNC:HGNC:34362|Ensembl:ENSG00000199352 +100169752 TEX36-AS1 HGNC:HGNC:49500|Ensembl:ENSG00000237675 +100169753 RNA5S2 HGNC:HGNC:34363|Ensembl:ENSG00000201588 +100169754 RNA5S3 HGNC:HGNC:34364|Ensembl:ENSG00000199337 +100169755 RNA5S4 HGNC:HGNC:34365|Ensembl:ENSG00000200381 +100169756 RNA5S5 HGNC:HGNC:34366|Ensembl:ENSG00000199396 +100169757 RNA5S6 HGNC:HGNC:34367|Ensembl:ENSG00000200624 +100169758 RNA5S7 HGNC:HGNC:34368|Ensembl:ENSG00000202521 +100169759 RNA5S8 HGNC:HGNC:34369|Ensembl:ENSG00000200343 +100169760 RNA5S9 HGNC:HGNC:34370|Ensembl:ENSG00000201321 +100169761 RNA5S10 HGNC:HGNC:34371|Ensembl:ENSG00000199910 +100169762 RNA5S11 HGNC:HGNC:34372|Ensembl:ENSG00000199334 +100169763 RNA5S12 HGNC:HGNC:34373|Ensembl:ENSG00000199270 +100169764 RNA5S13 HGNC:HGNC:34374|Ensembl:ENSG00000202526 +100169765 RNA5S14 HGNC:HGNC:34375|Ensembl:ENSG00000201355 +100169766 RNA5S15 HGNC:HGNC:34376|Ensembl:ENSG00000201925 +100169767 RNA5S16 HGNC:HGNC:34377|Ensembl:ENSG00000202257 +100169768 RNA5S17 HGNC:HGNC:34378|Ensembl:ENSG00000200370 +100169834 RNY4P19 HGNC:HGNC:34069 +100169835 RNY5P7 HGNC:HGNC:34088 +100169836 RNY5P9 HGNC:HGNC:34090 +100169837 RNY5P10 HGNC:HGNC:34091 +100169850 RNY4P7 HGNC:HGNC:34056 +100169851 PATE3 HGNC:HGNC:35426|Ensembl:ENSG00000236027|Vega:OTTHUMG00000165857 +100169881 MTPN-LUZP6 - +100169890 PEG3-AS1 HGNC:HGNC:35127 +100169951 SNAR-A3 HGNC:HGNC:34306 +100169952 SNAR-A5 HGNC:HGNC:34308 +100169953 SNAR-A7 HGNC:HGNC:34310 +100169954 SNAR-A11 HGNC:HGNC:34314 +100169955 SNAR-A9 HGNC:HGNC:34312 +100169956 SNAR-A4 HGNC:HGNC:34307 +100169957 SNAR-A6 HGNC:HGNC:34309 +100169958 SNAR-A8 HGNC:HGNC:34311 +100169959 SNAR-A13 HGNC:HGNC:34316 +100169989 DBIL5P2 HGNC:HGNC:38518|Ensembl:ENSG00000242412 +100170216 SNAR-A10 HGNC:HGNC:34313 +100170217 SNAR-B2 HGNC:HGNC:34318 +100170218 SNAR-C2 HGNC:HGNC:34320 +100170219 SNAR-C4 HGNC:HGNC:34322 +100170220 SNAR-E HGNC:HGNC:34325 +100170221 SNAR-H HGNC:HGNC:34329 +100170222 SNAR-I HGNC:HGNC:34330 +100170223 SNAR-C5 HGNC:HGNC:34323 +100170224 SNAR-B1 HGNC:HGNC:34317 +100170225 SNAR-C1 HGNC:HGNC:34319 +100170226 SNAR-C3 HGNC:HGNC:34321 +100170227 SNAR-D HGNC:HGNC:34324 +100170228 SNAR-G2 HGNC:HGNC:34328 +100170229 SRRM5 HGNC:HGNC:37248|Ensembl:ENSG00000226763|Vega:OTTHUMG00000165480 +100170765 ERICH4 HGNC:HGNC:34497|Ensembl:ENSG00000204978|Vega:OTTHUMG00000187130 +100170841 EPOP HGNC:HGNC:34493|Ensembl:ENSG00000273604|Vega:OTTHUMG00000188495 +100174857 GSTA9P HGNC:HGNC:49902 +100174949 TRIM59-IFT80 - +100174950 LOC100174950 - +100187710 CRCS6 MIM:612231 +100187711 CRCS7 MIM:612232 +100187716 MIR1224 MIM:611620|HGNC:HGNC:33923|Ensembl:ENSG00000221120|miRBase:MI0003764 +100187717 NNO3 MIM:611897 +100187724 DEL16P11.2 MIM:611913 +100187725 LOC100187725 - +100187749 ASDP MIM:105563 +100187761 AN MIM:110350 +100187828 HBD MIM:146350 +100187907 TRAP MIM:190445 +100188011 DIP MIM:263000 +100188278 FECD2 MIM:610158 +100188314 AUTS12 MIM:610838 +100188317 AUTS13 MIM:610908 +100188321 HYT8 MIM:611014 +100188328 PNKD2 MIM:611147 +100188340 AOS MIM:100300 +100188397 HLP MIM:144150 +100188695 DA4 MIM:609128 +100188748 STHAG5 MIM:610926 +100188754 AD14 MIM:611154 +100188765 CFTDX MIM:300580 +100188767 AGSPX MIM:300652 +100188768 SCAX5 MIM:300703 +100188769 HPCX2 MIM:300704 +100188771 AGA2 MIM:300710 +100188772 IHPS4 MIM:300711 +100188773 CFSS MIM:300712 +100188774 DFCTRPS MIM:300719 +100188775 LOAS MIM:308905 +100188776 HEY MIM:425500 +100188782 NIDDM4 MIM:608036 +100188784 AFA1 MIM:109200 +100188785 ITC1 - +100188787 WM1 MIM:153600 +100188788 DEL3Q29 MIM:609425 +100188789 HPC6 MIM:609558 +100188790 MGR8 MIM:609570 +100188791 CLLS1 MIM:609630 +100188792 MAFD3 MIM:609633 +100188793 BSZQTL MIM:609656 +100188794 BSZQTL2 MIM:609657 +100188795 AD11 MIM:609790 +100188796 GEFSP4 MIM:609800 +100188797 BMND6 MIM:609876 +100188798 SLEB5 MIM:609903 +100188800 ASPG4 MIM:609954 +100188801 ASRT3 MIM:609958 +100188802 ODS1 MIM:610064 +100188803 SLEB7 MIM:610065 +100188804 SLEB8 MIM:610066 +100188805 STBMS1 MIM:185100 +100188806 HDLCQ4 MIM:610239 +100188807 HYT5 MIM:610261 +100188808 HYT6 MIM:610262 +100188809 HPC7 MIM:610321 +100188810 ANIB5 MIM:610402 +100188811 WM2 MIM:610430 +100188812 RLS3 MIM:610438 +100188813 RLS4 MIM:610439 +100188814 DEL16P13.3 MIM:610543 +100188815 BSZQTL3 MIM:610649 +100188816 AUTS7 MIM:610676 +100188817 CLQTL2 MIM:610760 +100188818 HDLCQ5 MIM:610761 +100188819 HDLCQ6 MIM:610762 +100188820 AUTS11 MIM:610836 +100188821 OS4 MIM:610839 +100188822 MENAQ1 MIM:610873 +100188823 ASRT4 MIM:610906 +100188825 HYT7 MIM:610948 +100188826 HPC9 MIM:610997 +100188827 SQTL1 MIM:611003 +100188828 SQTL2 MIM:611004 +100188829 MTBS2 MIM:611046 +100188830 AD12 MIM:611073 +100188832 AUTS1 MIM:209850 +100188834 HPC10 MIM:611100 +100188835 CINN MIM:611109 +100188836 CHDS8 MIM:611139 +100188837 AD13 MIM:611152 +100188838 AD15 MIM:611155 +100188839 RLS5 MIM:611242 +100188840 ASRT6 MIM:611403 +100188841 CRCS2 MIM:611469 +100188842 ATFB5 MIM:611494 +100188843 MAFD5 MIM:611535 +100188844 MAFD6 MIM:611536 +100188845 CODA MIM:611543 +100188846 CELIAC6 MIM:611598 +100188847 MIR1225 MIM:611621|HGNC:HGNC:33931|Ensembl:ENSG00000221656|miRBase:MI0006311 +100188848 FMTLE MIM:611630 +100188849 FEB9 MIM:611634 +100188850 HSCR9 MIM:611644 +100188851 MGR12 MIM:611706 +100188852 SHEP8 MIM:611724 +100188853 BMND7 MIM:611738 +100188854 BMND8 MIM:611739 +100188855 MNDEC MIM:611863 +100188856 DEL22Q11.2 MIM:611867 +100188857 AAA3 MIM:611891 +100188858 ANIB6 MIM:611892 +100188859 EA7 MIM:611907 +100188860 CPROTQ MIM:611920 +100188861 EIG5 MIM:611934 +100188862 DUP3Q29 MIM:611936 +100188863 ENDO1 MIM:131200 +100188864 IH MIM:235000 +100188865 LMPH1B MIM:611944 +100188867 HPC14 MIM:611958 +100188868 HPC15 MIM:611959 +100188869 DEL15Q13.3 MIM:612001 +100188870 CELIAC8 MIM:612006 +100188871 CELIAC9 MIM:612007 +100188872 CELIAC10 MIM:612008 +100188873 CELIAC11 MIM:612009 +100188874 CELIAC12 MIM:612010 +100188875 CELIAC13 MIM:612011 +100188876 IHPS3 MIM:612017 +100188877 CHDS9 MIM:612030 +100188880 HPRHP MIM:612089 +100188881 MFT2 MIM:612099 +100188882 BMND9 MIM:612110 +100188883 BMND10 MIM:612113 +100188884 BMND11 MIM:612114 +100188885 ANIB7 MIM:612161 +100188886 ANIB8 MIM:612162 +100188887 CRCS5 MIM:612230 +100188891 ZNF123P MIM:194630|HGNC:HGNC:12906 +100188893 TOMM6 MIM:616168|HGNC:HGNC:34528|Ensembl:ENSG00000214736|Vega:OTTHUMG00000137505 +100188917 ESP33 - +100188945 CDCA4P4 HGNC:HGNC:49773 +100188947 HECTD2-AS1 HGNC:HGNC:48679 +100188949 LINC00426 HGNC:HGNC:42761|Ensembl:ENSG00000238121 +100188952 IBD12 MIM:612241 +100188953 LINC00092 HGNC:HGNC:31408|Ensembl:ENSG00000225194 +100188954 DNMBP-AS1 HGNC:HGNC:20431 +100188985 TRG-GCC2-4 HGNC:HGNC:34533 +100188986 TRH-GTG1-7 HGNC:HGNC:34536 +100188987 TRH-GTG1-5 HGNC:HGNC:34538 +100188988 TRH-GTG1-8 HGNC:HGNC:34537 +100188989 TRU-TCA3-1 HGNC:HGNC:34525 +100188990 TRV-AAC1-2 HGNC:HGNC:34542 +100188991 TRH-GTG1-1 HGNC:HGNC:34535 +100188992 TRV-AAC2-1 HGNC:HGNC:34543 +100188993 TRV-TAC1-1 HGNC:HGNC:34544 +100188994 TRD-GTC4-1 HGNC:HGNC:34551 +100188995 TRK-CTT6-1 HGNC:HGNC:34552 +100188996 TRN-GTT14-1 HGNC:HGNC:34553 +100188997 TRG-TCC4-1 HGNC:HGNC:34554 +100188998 TRQ-CTG7-1 HGNC:HGNC:34555 +100188999 TRK-CTT15-1 HGNC:HGNC:34556 +100189000 TRE-TTC12-1 HGNC:HGNC:34557 +100189001 TRY-GTA5-5 HGNC:HGNC:34558 +100189002 TRS-GCT2-1 HGNC:HGNC:34559 +100189003 TRL-CAA6-1 HGNC:HGNC:34560 +100189004 TRL-AAG1-3 HGNC:HGNC:34561 +100189005 TRN-GTT7-1 HGNC:HGNC:34562 +100189006 TRT-AGT1-3 HGNC:HGNC:34563 +100189007 TRE-CTC3-1 HGNC:HGNC:34564 +100189008 TRC-GCA11-1 HGNC:HGNC:34566 +100189009 TRL-CAG1-2 HGNC:HGNC:34568 +100189010 TRQ-TTG10-1 HGNC:HGNC:34569 +100189011 TRG-TCC2-6 HGNC:HGNC:34570 +100189012 TRR-TCT5-1 HGNC:HGNC:34571 +100189013 TRK-CTT1-2 HGNC:HGNC:34572 +100189014 TRV-AAC5-1 MIM:615307|HGNC:HGNC:34573 +100189015 TRX-CAT1-1 HGNC:HGNC:34574 +100189016 TRQ-CTG15-1 HGNC:HGNC:34575 +100189017 TRE-CTC1-5 HGNC:HGNC:34576 +100189018 TRL-CAG1-6 HGNC:HGNC:34577 +100189019 TRP-AGG2-1 HGNC:HGNC:34578 +100189020 TRP-AGG1-1 HGNC:HGNC:34579 +100189021 TRA-CGC3-1 HGNC:HGNC:34580 +100189022 TRY-GTA2-1 HGNC:HGNC:34581 +100189024 TRE-CTC1-6 HGNC:HGNC:34583 +100189025 TRR-TCG6-1 HGNC:HGNC:34584 +100189026 TRQ-TTG6-1 HGNC:HGNC:34585 +100189028 TRI-TAT2-2 HGNC:HGNC:34587 +100189029 TRC-GCA22-1 HGNC:HGNC:34588 +100189030 TRE-TTC2-1 HGNC:HGNC:34589 +100189031 TRE-TTC5-1 HGNC:HGNC:34590 +100189032 TRL-TAG3-1 HGNC:HGNC:34591 +100189033 TRA-CGC4-1 HGNC:HGNC:34592 +100189034 TRR-TCG5-1 HGNC:HGNC:34593 +100189035 TRT-CGT1-1 HGNC:HGNC:34594 +100189036 TRN-GTT2-4 HGNC:HGNC:34595 +100189037 TRS-CGA1-1 HGNC:HGNC:34596 +100189038 TRL-CAA3-1 HGNC:HGNC:34597 +100189039 TRG-TCC2-5 HGNC:HGNC:34598 +100189040 TRX-CAT1-4 HGNC:HGNC:34599 +100189041 TRS-CGA2-1 HGNC:HGNC:34600 +100189042 TRA-AGC6-1 HGNC:HGNC:34601 +100189043 TRL-AAG5-1 HGNC:HGNC:34602 +100189044 TRE-CTC8-1 HGNC:HGNC:34603 +100189045 TRG-CCC5-1 HGNC:HGNC:34604 +100189046 TRA-AGC4-1 HGNC:HGNC:34605 +100189047 TRA-AGC5-1 HGNC:HGNC:34606 +100189048 TRW-CCA3-2 HGNC:HGNC:34607 +100189049 TRC-GCA18-1 HGNC:HGNC:34608 +100189050 TRI-GAT1-2 HGNC:HGNC:34609 +100189051 TRK-TTT12-1 HGNC:HGNC:34610 +100189052 TRC-GCA2-2 HGNC:HGNC:34611 +100189053 TRK-TTT4-1 HGNC:HGNC:34612 +100189054 TRE-TTC13-1 HGNC:HGNC:34613 +100189055 NMTRS-TGA1-1 HGNC:HGNC:34614 +100189056 TRQ-CTG4-1 HGNC:HGNC:34615 +100189057 TRY-GTA9-1 HGNC:HGNC:34616 +100189058 NMTRQ-TTG14-1 HGNC:HGNC:34617 +100189059 TRN-GTT8-1 HGNC:HGNC:34618 +100189060 TRA-AGC13-2 HGNC:HGNC:34619 +100189061 TRD-GTC5-1 HGNC:HGNC:34620 +100189062 TRK-CTT4-1 HGNC:HGNC:34621 +100189063 TRE-TTC2-2 HGNC:HGNC:34622 +100189064 TRG-TCC2-1 HGNC:HGNC:34623 +100189065 TRH-GTG1-9 HGNC:HGNC:34624 +100189066 TRA-TGC5-1 HGNC:HGNC:34625 +100189067 TRL-TAA4-1 HGNC:HGNC:34626 +100189068 TRE-TTC8-1 HGNC:HGNC:34627 +100189069 TRN-GTT16-1 HGNC:HGNC:34628 +100189070 TRS-AGA4-1 HGNC:HGNC:34629 +100189071 TRI-AAT2-1 HGNC:HGNC:34630 +100189072 TRP-AGG2-4 HGNC:HGNC:34631 +100189073 TRV-CAC12-1 HGNC:HGNC:34632 +100189074 TRQ-TTG3-3 HGNC:HGNC:34633 +100189075 TRC-GCA12-1 HGNC:HGNC:34634 +100189077 TRS-AGA2-2 HGNC:HGNC:34637 +100189078 TRR-CCT1-1 HGNC:HGNC:34638 +100189079 TRN-GTT16-3 HGNC:HGNC:34639 +100189080 TRSUP-TTA1-1 HGNC:HGNC:34640 +100189081 TRG-GCC6-1 HGNC:HGNC:34641 +100189082 TRA-TGC6-1 HGNC:HGNC:34642 +100189083 TRN-GTT2-3 HGNC:HGNC:34643 +100189084 TRR-CCG1-2 HGNC:HGNC:34644 +100189085 TRM-CAT7-1 HGNC:HGNC:34645 +100189086 TRT-CGT2-1 HGNC:HGNC:34646 +100189087 TRD-GTC7-1 HGNC:HGNC:34647 +100189088 TRP-TGG3-2 HGNC:HGNC:34648 +100189089 TRL-CAG2-2 HGNC:HGNC:34649 +100189090 TRC-GCA4-1 HGNC:HGNC:34650 +100189091 TRE-CTC1-2 HGNC:HGNC:34651 +100189092 TRA-AGC7-1 HGNC:HGNC:34653 +100189093 TRA-AGC2-1 HGNC:HGNC:34654 +100189094 TRX-CAT1-3 HGNC:HGNC:34655 +100189095 TRI-AAT8-1 HGNC:HGNC:34656 +100189096 TRN-GTT17-1 HGNC:HGNC:34657 +100189097 TRC-GCA3-1 HGNC:HGNC:34658 +100189098 TRK-TTT8-1 HGNC:HGNC:34659 +100189099 TRR-ACG2-3 HGNC:HGNC:34660 +100189100 TRM-CAT4-1 HGNC:HGNC:34661 +100189101 TRV-CAC7-1 HGNC:HGNC:34662 +100189102 TRY-GTA5-2 HGNC:HGNC:34663 +100189103 TRR-ACG2-1 HGNC:HGNC:34664 +100189104 TRK-TTT11-1 HGNC:HGNC:34665 +100189105 TRC-GCA2-3 HGNC:HGNC:34666 +100189106 TRA-AGC12-3 HGNC:HGNC:34667 +100189107 TRK-CTT1-1 HGNC:HGNC:34668 +100189108 TRN-GTT11-1 HGNC:HGNC:34669 +100189109 TRR-TCT3-1 HGNC:HGNC:34670 +100189110 TRK-CTT2-4 HGNC:HGNC:34671 +100189111 TRM-CAT3-2 HGNC:HGNC:34673 +100189112 TRW-CCA3-3 HGNC:HGNC:34674 +100189113 TRE-CTC17-1 HGNC:HGNC:34675 +100189114 TRA-TGC2-1 HGNC:HGNC:34676 +100189115 TRR-TCT3-2 HGNC:HGNC:34677 +100189116 TRA-AGC20-1 HGNC:HGNC:34678 +100189117 TRA-AGC15-1 HGNC:HGNC:34679 +100189118 TRL-AAG4-1 HGNC:HGNC:34680 +100189119 TRK-CTT3-1 HGNC:HGNC:34681 +100189120 TRD-GTC2-5 HGNC:HGNC:34682 +100189121 TRQ-CTG1-3 HGNC:HGNC:34683 +100189122 TRK-TTT3-1 HGNC:HGNC:34684 +100189123 TRW-CCA1-1 HGNC:HGNC:34685 +100189124 TRP-CGG1-3 HGNC:HGNC:34686 +100189125 TRK-TTT1-1 HGNC:HGNC:34687 +100189126 TRN-GTT1-1 HGNC:HGNC:34688 +100189127 TRN-GTT3-2 HGNC:HGNC:34689 +100189128 TRA-AGC10-1 HGNC:HGNC:34690 +100189129 TRE-TTC11-1 HGNC:HGNC:34691 +100189130 TRL-CAG2-1 HGNC:HGNC:34692 +100189131 TRI-TAT2-3 HGNC:HGNC:34693 +100189132 TRI-GAT1-1 HGNC:HGNC:34694 +100189133 TRR-TCT1-1 HGNC:HGNC:34695 +100189134 TRD-GTC2-4 HGNC:HGNC:34696 +100189135 TRM-CAT2-1 HGNC:HGNC:34697 +100189136 TRP-AGG2-7 HGNC:HGNC:34698 +100189137 TRF-GAA1-1 HGNC:HGNC:34699 +100189138 TRQ-TTG2-1 HGNC:HGNC:34700 +100189139 TRL-CAG1-5 HGNC:HGNC:34701 +100189140 TRQ-CTG3-2 HGNC:HGNC:34702 +100189141 TRG-TCC2-3 HGNC:HGNC:34703 +100189142 TRV-CAC8-1 HGNC:HGNC:34704 +100189143 TRT-AGT6-1 HGNC:HGNC:34705 +100189144 TRC-GCA1-1 HGNC:HGNC:34706 +100189145 TRF-GAA5-1 HGNC:HGNC:34707 +100189146 TRC-GCA16-1 HGNC:HGNC:34708 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TRC-GCA14-1 HGNC:HGNC:35005 +100189436 TRW-CCA3-1 HGNC:HGNC:35006 +100189437 TRY-GTA5-1 HGNC:HGNC:35007 +100189438 TRT-AGT5-1 HGNC:HGNC:35008 +100189439 TRK-CTT13-1 HGNC:HGNC:35009 +100189440 TRE-CTC12-1 HGNC:HGNC:35010 +100189441 TRL-TAG4-1 HGNC:HGNC:35011 +100189442 TRSUP-CTA2-1 HGNC:HGNC:35012 +100189443 TRR-CCT7-1 HGNC:HGNC:35013 +100189444 TRQ-TTG7-1 HGNC:HGNC:35014 +100189445 NMTRQ-TTG7-1 HGNC:HGNC:35015 +100189446 TRF-GAA8-1 HGNC:HGNC:35016 +100189447 TRC-GCA25-1 HGNC:HGNC:35017 +100189448 NMTRQ-TTG8-1 HGNC:HGNC:35018 +100189449 TRR-CCT6-2 HGNC:HGNC:35019 +100189450 TRE-CTC14-1 HGNC:HGNC:35020 +100189451 NMTRQ-TTG9-1 HGNC:HGNC:35022 +100189452 TRQ-CTG11-1 HGNC:HGNC:35023 +100189453 TRSUP-TTA3-1 HGNC:HGNC:35024 +100189454 TRE-TTC10-1 HGNC:HGNC:35025 +100189455 TRP-GGG1-1 HGNC:HGNC:35026 +100189456 NMTRL-TAA6-1 HGNC:HGNC:35027 +100189457 TRE-TTC7-1 HGNC:HGNC:35028 +100189458 TRG-CCC7-1 HGNC:HGNC:35030 +100189459 TRE-CTC13-1 HGNC:HGNC:35031 +100189460 TRG-TCC5-1 HGNC:HGNC:35032 +100189461 NMTRQ-CTG1-1 HGNC:HGNC:35033 +100189462 TRI-AAT10-1 HGNC:HGNC:35034 +100189463 NMTRP-TGG1-1 HGNC:HGNC:35035 +100189464 TRK-CTT12-1 HGNC:HGNC:35036 +100189465 TRE-TTC6-1 HGNC:HGNC:35037 +100189466 NMTRL-TAA5-1 HGNC:HGNC:35038 +100189467 TRK-CTT14-1 HGNC:HGNC:35039 +100189468 TRA-AGC23-1 HGNC:HGNC:35040 +100189469 TRA-TGC10-1 HGNC:HGNC:35041 +100189470 TRSUP-CTA3-1 HGNC:HGNC:35043 +100189471 TRF-GAA12-1 HGNC:HGNC:35044 +100189472 TRF-GAA11-1 HGNC:HGNC:35045 +100189473 TRQ-TTG5-1 HGNC:HGNC:35046 +100189474 TRI-AAT11-1 HGNC:HGNC:35047 +100189475 NMTRQ-TTG1-1 HGNC:HGNC:35048 +100189476 TRP-AGG6-1 HGNC:HGNC:35049 +100189477 TRV-CAC14-1 HGNC:HGNC:35050 +100189478 NMTRQ-TTG12-1 HGNC:HGNC:35051 +100189479 TRV-CAC11-2 HGNC:HGNC:35052 +100189480 TRK-TTT10-1 HGNC:HGNC:35053 +100189481 TRI-AAT12-1 HGNC:HGNC:35054 +100189482 TRP-AGG5-1 HGNC:HGNC:35055 +100189483 TRP-TGG4-1 HGNC:HGNC:35056 +100189484 TRE-TTC15-1 HGNC:HGNC:35057 +100189485 TRE-TTC14-1 HGNC:HGNC:35058 +100189486 TRG-CCC4-1 HGNC:HGNC:35059 +100189487 TRS-AGA7-1 HGNC:HGNC:35060 +100189488 TRE-CTC11-1 HGNC:HGNC:35061 +100189489 NMTRQ-TTG4-1 HGNC:HGNC:35062 +100189490 TRN-GTT23-1 HGNC:HGNC:35064 +100189491 TRE-CTC7-1 HGNC:HGNC:35065 +100189492 TRE-CTC18-1 HGNC:HGNC:35067 +100189493 TRL-AAG7-1 HGNC:HGNC:35068 +100189494 TRE-CTC9-1 HGNC:HGNC:35069 +100189495 TRD-GTC10-1 HGNC:HGNC:35070 +100189496 TRY-GTA12-1 HGNC:HGNC:35071 +100189497 TRF-GAA10-1 HGNC:HGNC:35072 +100189498 TRG-CCC6-1 HGNC:HGNC:35073 +100189499 TRL-CAA7-1 HGNC:HGNC:35074 +100189500 TRV-CAC13-1 HGNC:HGNC:35075 +100189501 NMTRQ-TTG11-1 HGNC:HGNC:35076 +100189502 TRR-CCT8-1 HGNC:HGNC:35077 +100189503 TRQ-CTG16-1 HGNC:HGNC:35078 +100189504 TRK-TTT15-1 HGNC:HGNC:35079 +100189505 TRQ-TTG8-1 HGNC:HGNC:35080 +100189506 TRE-CTC4-1 HGNC:HGNC:35081 +100189507 TRY-GTA11-1 HGNC:HGNC:35082 +100189508 TRC-ACA1-1 HGNC:HGNC:35083 +100189509 TRQ-TTG9-1 HGNC:HGNC:35084 +100189510 NMTRQ-TTG6-1 HGNC:HGNC:35085 +100189511 TRG-TCC6-1 HGNC:HGNC:35086 +100189512 NMTRS-TGA3-1 HGNC:HGNC:35087 +100189513 NMTRV-TAC1-1 HGNC:HGNC:35088 +100189514 TRK-TTT14-1 HGNC:HGNC:35089 +100189515 TRP-TGG5-1 HGNC:HGNC:35090 +100189516 NMTRQ-TTG2-1 HGNC:HGNC:35091 +100189517 TRN-GTT10-1 HGNC:HGNC:35092 +100189518 TRE-TTC9-1 HGNC:HGNC:35093 +100189519 TRK-TTT17-1 HGNC:HGNC:35094 +100189520 NMTRL-TAA3-1 HGNC:HGNC:35095 +100189522 NMTRL-TAA2-1 HGNC:HGNC:35097 +100189523 TRQ-CTG14-1 HGNC:HGNC:38574 +100189524 NMTRQ-TTG10-1 HGNC:HGNC:35099 +100189525 NMTRS-TGA2-1 HGNC:HGNC:35100 +100189526 TRS-ACT1-1 HGNC:HGNC:35102 +100189527 TRE-CTC15-1 HGNC:HGNC:35104 +100189528 TRE-CTC16-1 HGNC:HGNC:35105 +100189529 TRA-TGC9-1 HGNC:HGNC:35106 +100189530 TRP-AGG4-1 HGNC:HGNC:35107 +100189531 TRQ-CTG9-1 HGNC:HGNC:35108 +100189532 TRE-CTC10-1 HGNC:HGNC:35109 +100189533 TRF-GAA9-1 HGNC:HGNC:35110 +100189534 TRN-GTT22-1 HGNC:HGNC:35111 +100189535 NMTRQ-TTG13-1 HGNC:HGNC:35112 +100189536 TRK-CTT16-1 HGNC:HGNC:35113 +100189537 TRR-CCT9-1 HGNC:HGNC:35114 +100189538 TRQ-CTG13-1 HGNC:HGNC:35115 +100189539 TRK-TTT13-1 HGNC:HGNC:35116 +100189540 NMTRQ-TTG15-1 HGNC:HGNC:35117 +100189541 TRV-CAC1-4 HGNC:HGNC:34541 +100189589 DCTN1-AS1 HGNC:HGNC:44151|Ensembl:ENSG00000237737 +100190785 IS4 MIM:612238 +100190786 CILD8 MIM:612274 +100190787 GEFSP6 MIM:612279 +100190788 IBD20 MIM:612288 +100190789 TSHQTL1 MIM:612306 +100190790 ADHD5 MIM:612311 +100190791 ADHD6 MIM:612312 +100190799 LDHAP2 HGNC:HGNC:6537 +100190800 LDHAP7 HGNC:HGNC:23144 +100190922 LOC100190922 - +100190923 EIF4EBP2P2 HGNC:HGNC:49317 +100190924 EIF4EBP2P3 HGNC:HGNC:49318 +100190926 IBD19 MIM:612278 +100190928 SLEB12 MIM:612254 +100190929 IBD15 MIM:612255 +100190930 IBD16 MIM:612259 +100190931 IBD18 MIM:612262 +100190932 CMM7 MIM:612263 +100190934 LOC100190934 - +100190938 RAMP2-AS1 HGNC:HGNC:44358|Ensembl:ENSG00000197291 +100190939 TPT1-AS1 HGNC:HGNC:43686 +100190940 LINC02418 HGNC:HGNC:53348|Ensembl:ENSG00000214039 +100190947 SUPT4H1P1 HGNC:HGNC:33981 +100190949 C5orf52 HGNC:HGNC:35121|Ensembl:ENSG00000187658|Vega:OTTHUMG00000154518 +100190952 NDUFB1P1 HGNC:HGNC:30893 +100190954 EXOSC3P2 HGNC:HGNC:33990 +100190955 FAM32DP HGNC:HGNC:34240 +100190956 FAM32EP HGNC:HGNC:34241 +100190982 POROK5 MIM:612293 +100190983 DEL2Q32Q33 MIM:612313 +100190984 DEL1Q43Q44 MIM:612337 +100190985 IS5 MIM:612239 +100190986 LOC100190986 - +100190987 FDPSP10 HGNC:HGNC:39087 +100191039 RPL36AP33 HGNC:HGNC:36475 +100191040 C2CD4D HGNC:HGNC:37210|Ensembl:ENSG00000225556|Vega:OTTHUMG00000167218 +100191063 SNAR-A14 HGNC:HGNC:34338 +100192204 PPIAP30 HGNC:HGNC:44878|Ensembl:ENSG00000206448 +100192306 JAWAD MIM:251255 +100192307 MUSQTL1 MIM:612343 +100192308 DEL2Q31 MIM:612345 +100192311 MUSTQTL1 MIM:612083 +100192312 IBD21 MIM:612354 +100192378 ZFHX4-AS1 HGNC:HGNC:44165|Ensembl:ENSG00000253661 +100192379 PP12613 Ensembl:ENSG00000226757 +100192386 FLJ16779 Ensembl:ENSG00000275620 +100192388 LOC100192388 - +100192389 LOC100192389 - +100192420 LINC01634 HGNC:HGNC:52421|Ensembl:ENSG00000235295 +100192426 LOC100192426 Ensembl:ENSG00000266149 +100194425 BCAP31P1 HGNC:HGNC:51323 +100194426 BCAP31P2 HGNC:HGNC:51324 +100196909 ALPQTL1 MIM:171720 +100196910 POROK2 MIM:175850 +100196911 POROK6 MIM:612353 +100196912 MAFD8 MIM:612357 +100196913 SCZD14 MIM:612361 +100196914 ALPQTL2 MIM:612367 +100196915 ALPQTL3 MIM:612368 +100196916 ALPQTL4 MIM:612369 +100196917 MAFD9 MIM:612372 +100196918 SLEB13 MIM:612378 +100196919 SS3 MIM:612388 +100196944 LOC100196944 - +100216001 LINC00704 HGNC:HGNC:44678|Ensembl:ENSG00000231298 +100216336 RPS24P8 HGNC:HGNC:37016 +100216337 LOC100216337 - +100216338 RPS24P13 HGNC:HGNC:36805 +100216339 RPS24P6 HGNC:HGNC:36240 +100216340 RPS24P16 HGNC:HGNC:35542 +100216341 RPS24P17 HGNC:HGNC:36348 +100216342 RPS24P7 HGNC:HGNC:35737 +100216344 DYT17 MIM:612406|HGNC:HGNC:35416 +100216346 LOC100216346 - +100216355 LOC100216355 - +100216356 LOC100216356 - +100216466 DNM1P43 HGNC:HGNC:35193 +100216479 FAR2P2 HGNC:HGNC:49279 +100216483 DEL18Q MIM:601808 +100216484 NRCLP4 MIM:612417 +100216487 AKIRIN2P1 HGNC:HGNC:50796 +100216488 LOC100216488 - +100216505 DNM1P24 HGNC:HGNC:35171 +100216506 DNM1P25 HGNC:HGNC:35172 +100216507 DNM1P26 HGNC:HGNC:35173 +100216514 DNM1P27 HGNC:HGNC:35174 +100216515 DNM1P36 HGNC:HGNC:35186 +100216516 DNM1P37 HGNC:HGNC:35187 +100216517 DNM1P38 HGNC:HGNC:35188 +100216518 DNM1P39 HGNC:HGNC:35189 +100216542 DNM1P45 HGNC:HGNC:35195 +100216544 DNM1P47 HGNC:HGNC:35200 +100216545 KMT2E-AS1 HGNC:HGNC:40845 +100216546 LINC01004 HGNC:HGNC:48961 +100217367 LOC100217367 - +100217370 DEL1Q21 MIM:612474 +100217371 DUP1Q21 MIM:612475 +100217387 AGA3 MIM:612421 +100233146 HINT1P2 HGNC:HGNC:38049 +100233147 ARHI1 MIM:612448 +100233156 LOC100233156 - +100233157 BMIQ13 MIM:612459 +100233158 BMIQ14 MIM:612460 +100233159 WAGRO MIM:612469 +100233198 TMX2P1 HGNC:HGNC:49916 +100233209 PCED1B-AS1 HGNC:HGNC:44166|Ensembl:ENSG00000247774 +100233226 MCI2 MIM:608557 +100233227 SLI4 MIM:612514 +100240702 PLSA1 MIM:611637 +100240707 GAPDHP42 HGNC:HGNC:37799 +100240708 GAPDHP43 HGNC:HGNC:37800 +100240709 GAPDHP44 HGNC:HGNC:37801 +100240710 GAPDHP45 HGNC:HGNC:37802 +100240711 GAPDHP46 HGNC:HGNC:37804 +100240712 GAPDHP47 HGNC:HGNC:37803 +100240713 GAPDHP48 HGNC:HGNC:37805 +100240714 LOC100240714 - +100240728 LOC100240728 Ensembl:ENSG00000225488 +100240730 DUP7Q11.23 MIM:609757 +100240731 DEL15Q15.3 MIM:611102 +100240732 IBD22 MIM:612380 +100240733 IBD23 MIM:612381 +100240734 LOC100240734 - +100240735 LOC100240735 Ensembl:ENSG00000250654 +100240736 DEL11P15P14 MIM:606528 +100240737 DEL1P36 MIM:607872 +100240738 DUP22Q11.2 MIM:608363 +100240739 DUP18PDEL18Q MIM:609334 +100240740 DEL2P16.1-P15 MIM:612513 +100240747 DEL18P MIM:146390 +100240748 DEL9P MIM:158170 +100240749 LOC100240749 - +100268168 LOC100268168 Ensembl:ENSG00000204758 +100270639 IHPS5 MIM:612525 +100270641 MYP16 MIM:612554|HGNC:HGNC:35441 +100270642 CLLS3 MIM:612557 +100270643 CLLS4 MIM:612558 +100270644 CLLS5 MIM:612559 +100270647 LOC100270647 - +100270648 NIFKP3 HGNC:HGNC:44951 +100270670 LOC100270670 - +100270673 FABP5P12 HGNC:HGNC:31067 +100270679 LINC01432 HGNC:HGNC:50745|Ensembl:ENSG00000234435 +100270680 CASC11 HGNC:HGNC:48939|Ensembl:ENSG00000249375 +100270709 FTH1P27 HGNC:HGNC:39091 +100270746 LOC100270746 - +100270753 RPL21P112 HGNC:HGNC:36526 +100270754 RPL7AP72 HGNC:HGNC:36442 +100270755 RPSAP63 HGNC:HGNC:35581 +100270790 GNL2P1 HGNC:HGNC:50779 +100270794 STQTL10 MIM:612221 +100270795 STQTL11 MIM:612223 +100270796 STQTL13 MIM:612226 +100270797 STQTL14 MIM:612228 +100270798 IBD24 MIM:612566 +100270799 IBD25 MIM:612567 +100270800 SHFLD3 MIM:612576 +100270801 STQTL15 MIM:612578 +100270802 STQTL16 MIM:612579 +100270803 DEL6PTER MIM:612582 +100270804 LOC100270804 - +100270823 RPL7P11 HGNC:HGNC:35667 +100270825 RPL9P12 HGNC:HGNC:36728 +100270826 RPS2P13 HGNC:HGNC:36021 +100270827 RPS2P14 HGNC:HGNC:36389 +100270828 RPL37P9 HGNC:HGNC:35688 +100270829 RPL39P12 HGNC:HGNC:36166 +100270832 RPL5P9 HGNC:HGNC:36557 +100270833 RPL5P12 HGNC:HGNC:36221 +100270834 RPL5P13 HGNC:HGNC:37023 +100270835 RPL5P14 HGNC:HGNC:35924 +100270836 RPL5P15 HGNC:HGNC:36769 +100270837 RPL5P16 HGNC:HGNC:36009 +100270838 RPL5P21 HGNC:HGNC:37029 +100270839 RPL5P17 HGNC:HGNC:36605 +100270840 RPL5P23 HGNC:HGNC:36553 +100270841 RPL5P24 HGNC:HGNC:35828 +100270843 RPL6P15 HGNC:HGNC:36903 +100270844 RPL6P5 HGNC:HGNC:36199 +100270845 RPL6P6 HGNC:HGNC:36673 +100270846 RPL6P21 HGNC:HGNC:35994 +100270847 RPL6P9 HGNC:HGNC:36484 +100270848 RPL6P7 HGNC:HGNC:35801 +100270850 RPL7P15 HGNC:HGNC:36740 +100270851 RPL7P17 HGNC:HGNC:36116 +100270852 RPL7P18 HGNC:HGNC:36949 +100270853 RPL7P19 HGNC:HGNC:36268 +100270854 RPL8P3 HGNC:HGNC:36407 +100270855 RPL9P10 HGNC:HGNC:35686 +100270856 RPL9P13 HGNC:HGNC:36558 +100270857 RPL9P15 HGNC:HGNC:35539 +100270858 RPS2P15 HGNC:HGNC:36468 +100270859 RPS2P19 HGNC:HGNC:35786 +100270860 RPS2P16 HGNC:HGNC:36865 +100270861 RPS2P22 HGNC:HGNC:35506 +100270862 RPS3P4 HGNC:HGNC:36616 +100270864 RPS6P2 HGNC:HGNC:36446 +100270865 RPS6P10 HGNC:HGNC:36730 +100270866 RPS6P11 HGNC:HGNC:36270 +100270867 RPS6P12 HGNC:HGNC:36375 +100270868 RPS7P2 HGNC:HGNC:36079 +100270869 RPS7P6 HGNC:HGNC:36334 +100270870 RPS7P7 HGNC:HGNC:35690 +100270871 RPS8P6 HGNC:HGNC:36947 +100270872 RPSAP16 HGNC:HGNC:35478 +100270873 RPSAP17 HGNC:HGNC:35707 +100270874 RPSAP22 HGNC:HGNC:36435 +100270875 RPSAP23 HGNC:HGNC:36742 +100270876 RPSAP34 HGNC:HGNC:36643 +100270877 RPL21P21 HGNC:HGNC:35728 +100270878 RPL21P22 HGNC:HGNC:36550 +100270879 RPL21P23 HGNC:HGNC:36205 +100270880 RPL21P24 HGNC:HGNC:35702 +100270881 RPL21P25 HGNC:HGNC:36785 +100270882 RPL21P26 HGNC:HGNC:35910 +100270883 RPL26P7 HGNC:HGNC:37030 +100270884 RPL26P8 HGNC:HGNC:36192 +100270885 RPL26P9 HGNC:HGNC:36180 +100270886 RPL26P10 HGNC:HGNC:36323 +100270887 RPL31P12 HGNC:HGNC:35546 +100270888 RPL32P6 HGNC:HGNC:36655 +100270889 RPL34P4 HGNC:HGNC:36665 +100270890 RPL37P7 HGNC:HGNC:36499 +100270891 RPL39P6 HGNC:HGNC:35803 +100270892 RPL39P7 HGNC:HGNC:36651 +100270893 RPL39P8 HGNC:HGNC:36329 +100270894 RPL39P9 HGNC:HGNC:35580 +100270895 RPL7AP15 HGNC:HGNC:36873 +100270896 RPL7AP16 HGNC:HGNC:35898 +100270897 RPL7AP17 HGNC:HGNC:36501 +100270898 RPS11P3 HGNC:HGNC:35870 +100270899 RPS20P5 HGNC:HGNC:36367 +100270900 RPS20P6 HGNC:HGNC:35629 +100270901 RPS20P7 HGNC:HGNC:35911 +100270902 RPS26P14 HGNC:HGNC:36992 +100270903 RPS29P6 HGNC:HGNC:35718 +100270904 RPS3AP11 HGNC:HGNC:36825 +100270905 RPS3AP12 HGNC:HGNC:35527 +100270906 RPL5P19 HGNC:HGNC:36604 +100270907 RPL6P12 HGNC:HGNC:35681 +100270908 RPL7P30 HGNC:HGNC:36151 +100270909 RPL7P31 HGNC:HGNC:36988 +100270910 RPS2P23 HGNC:HGNC:35760 +100270911 RPS2P30 HGNC:HGNC:36987 +100270912 RPS2P24 HGNC:HGNC:35887 +100270913 RPS2P25 HGNC:HGNC:36410 +100270914 RPS7P12 HGNC:HGNC:36147 +100270915 RPSAP37 HGNC:HGNC:35844 +100270916 RPSAP35 HGNC:HGNC:36447 +100270917 RPSAP40 HGNC:HGNC:36828 +100270918 RPSAP41 HGNC:HGNC:36663 +100270919 RPSAP42 HGNC:HGNC:36265 +100270920 RPL12P15 HGNC:HGNC:36619 +100270921 RPL12P21 HGNC:HGNC:36845 +100270922 RPL12P22 HGNC:HGNC:35762 +100270923 RPL12P20 HGNC:HGNC:36968 +100270924 RPL12P24 HGNC:HGNC:35952 +100270925 RPL12P23 HGNC:HGNC:36408 +100270926 RPL12P25 HGNC:HGNC:37008 +100270927 RPL13P9 HGNC:HGNC:36587 +100270928 RPL13P8 HGNC:HGNC:35513 +100270930 RPL14P2 HGNC:HGNC:35962 +100270933 RPL15P6 HGNC:HGNC:36185 +100270934 RPL15P8 HGNC:HGNC:36390 +100270935 RPL15P9 HGNC:HGNC:36466 +100270936 RPL17P10 HGNC:HGNC:35838 +100270937 RPL17P11 HGNC:HGNC:36509 +100270938 RPL17P12 HGNC:HGNC:36779 +100270939 RPL17P13 HGNC:HGNC:36378 +100270940 RPL17P28 HGNC:HGNC:36055 +100270941 RPL17P14 HGNC:HGNC:35806 +100270942 RPL17P32 HGNC:HGNC:36492 +100270943 RPL17P17 HGNC:HGNC:35515 +100270944 RPL18P5 HGNC:HGNC:36425 +100270945 RPL18P7 HGNC:HGNC:35936 +100270946 RPL19P6 HGNC:HGNC:36795 +100270948 RPL19P10 HGNC:HGNC:36534 +100270950 RPL19P11 HGNC:HGNC:36953 +100270951 RPL19P14 HGNC:HGNC:35684 +100270952 RPL21P27 HGNC:HGNC:36371 +100270953 RPL21P33 HGNC:HGNC:36686 +100270954 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HGNC:HGNC:36101 +100271445 RPL21P121 HGNC:HGNC:36429 +100271446 RPL21P118 HGNC:HGNC:35954 +100271447 RPL21P122 HGNC:HGNC:36990 +100271448 RPL21P123 HGNC:HGNC:35691 +100271449 RPL21P126 HGNC:HGNC:35959 +100271450 RPL21P124 HGNC:HGNC:36060 +100271451 RPL21P129 HGNC:HGNC:36747 +100271452 RPL21P127 HGNC:HGNC:36099 +100271453 RPL21P130 HGNC:HGNC:36453 +100271455 RPL22P21 HGNC:HGNC:35547 +100271456 RPL23AP27 HGNC:HGNC:36497 +100271457 RPL23AP28 HGNC:HGNC:36727 +100271458 RPL23AP29 HGNC:HGNC:36355 +100271459 RPL23AP30 HGNC:HGNC:35617 +100271460 RPL23AP31 HGNC:HGNC:35777 +100271461 RPL23AP39 HGNC:HGNC:36470 +100271462 RPL23AP40 HGNC:HGNC:35587 +100271464 RPL23AP51 HGNC:HGNC:36040 +100271465 RPL23AP52 HGNC:HGNC:36723 +100271466 RPL23AP54 HGNC:HGNC:36689 +100271467 RPL23AP55 HGNC:HGNC:35997 +100271469 RPL26P31 HGNC:HGNC:36907 +100271470 RPL26P34 HGNC:HGNC:36249 +100271471 RPL26P27 HGNC:HGNC:36735 +100271472 RPL29P22 HGNC:HGNC:35675 +100271474 RPL29P29 HGNC:HGNC:36577 +100271475 RPL31P51 HGNC:HGNC:35600 +100271476 RPL31P52 HGNC:HGNC:36607 +100271477 RPL31P53 HGNC:HGNC:35749 +100271478 RPL31P56 HGNC:HGNC:36336 +100271479 RPL31P46 HGNC:HGNC:35559 +100271480 RPL31P59 HGNC:HGNC:36975 +100271481 RPL31P47 HGNC:HGNC:36124 +100271482 RPL31P62 HGNC:HGNC:36569 +100271483 RPL31P54 HGNC:HGNC:36077 +100271485 RPL31P58 HGNC:HGNC:35862 +100271486 RPL31P60 HGNC:HGNC:36123 +100271487 RPL31P61 HGNC:HGNC:35635 +100271488 RPL32P32 HGNC:HGNC:36024 +100271489 RPL32P24 HGNC:HGNC:36722 +100271490 RPL32P25 HGNC:HGNC:35721 +100271491 RPL32P26 HGNC:HGNC:36027 +100271492 RPL32P30 HGNC:HGNC:36729 +100271493 RPL32P33 HGNC:HGNC:36231 +100271494 RPL34P19 HGNC:HGNC:36925 +100271495 RPL34P21 HGNC:HGNC:35677 +100271498 RPL34P22 HGNC:HGNC:36454 +100271499 RPL34P23 HGNC:HGNC:35820 +100271500 RPL34P28 HGNC:HGNC:36781 +100271501 RPL34P25 HGNC:HGNC:35895 +100271502 RPL34P32 HGNC:HGNC:36902 +100271503 RPL34P29 HGNC:HGNC:35631 +100271504 RPL34P35 HGNC:HGNC:35798 +100271505 RPL34P30 HGNC:HGNC:36477 +100271506 RPL35AP21 HGNC:HGNC:36814 +100271507 RPL35AP22 HGNC:HGNC:35932 +100271508 RPL36AP24 HGNC:HGNC:36252 +100271509 RPL36AP28 HGNC:HGNC:36702 +100271510 RPL36AP29 HGNC:HGNC:36897 +100271511 RPL36AP30 HGNC:HGNC:36216 +100271512 RPL36AP32 HGNC:HGNC:36540 +100271513 RPL36AP34 HGNC:HGNC:35882 +100271515 RPL37P19 HGNC:HGNC:35576 +100271516 RPL37P21 HGNC:HGNC:36256 +100271517 RPL39P25 HGNC:HGNC:37002 +100271518 RPL39P26 HGNC:HGNC:35900 +100271519 RPL39P30 HGNC:HGNC:36979 +100271520 RPL39P28 HGNC:HGNC:35619 +100271521 RPL39P33 HGNC:HGNC:36315 +100271522 RPL39P29 HGNC:HGNC:35808 +100271523 RPL39P34 HGNC:HGNC:36528 +100271524 RPL39P35 HGNC:HGNC:35815 +100271525 RPL39P31 HGNC:HGNC:36488 +100271526 RPL39P36 HGNC:HGNC:36076 +100271528 RPL39P37 HGNC:HGNC:36282 +100271529 RPL39P38 HGNC:HGNC:36935 +100271530 RPL39P39 HGNC:HGNC:36514 +100271531 RPL39P40 HGNC:HGNC:35823 +100271532 RPL39P41 HGNC:HGNC:35941 +100271533 RPL7AP51 HGNC:HGNC:36826 +100271534 RPL7AP52 HGNC:HGNC:36233 +100271535 RPL7AP55 HGNC:HGNC:36314 +100271536 RPL7AP56 HGNC:HGNC:35585 +100271537 RPL7AP57 HGNC:HGNC:36551 +100271538 RPL7AP60 HGNC:HGNC:35859 +100271539 RPL7AP61 HGNC:HGNC:35482 +100271542 RPL7AP67 HGNC:HGNC:35537 +100271543 RPL7AP65 HGNC:HGNC:37031 +100271545 RPL7AP69 HGNC:HGNC:36697 +100271546 RPS10P25 HGNC:HGNC:36532 +100271547 RPS10P20 HGNC:HGNC:35829 +100271548 RPS10P26 HGNC:HGNC:36321 +100271549 RPS12P20 HGNC:HGNC:36187 +100271550 RPS12P21 HGNC:HGNC:36464 +100271551 RPS12P24 HGNC:HGNC:35561 +100271552 RPS12P27 HGNC:HGNC:35892 +100271553 RPS12P28 HGNC:HGNC:36972 +100271555 RPS12P30 HGNC:HGNC:36813 +100271556 RPS12P32 HGNC:HGNC:35571 +100271557 RPS15AP22 HGNC:HGNC:36305 +100271558 RPS15AP23 HGNC:HGNC:36718 +100271560 RPS20P28 HGNC:HGNC:36452 +100271561 RPS20P29 HGNC:HGNC:36237 +100271562 RPS20P30 HGNC:HGNC:36626 +100271563 RPS20P31 HGNC:HGNC:35767 +100271564 RPS20P33 HGNC:HGNC:36725 +100271565 RPS20P34 HGNC:HGNC:36668 +100271566 RPS20P35 HGNC:HGNC:36929 +100271567 RPS26P41 HGNC:HGNC:36062 +100271568 RPS26P42 HGNC:HGNC:36243 +100271569 RPS26P44 HGNC:HGNC:36927 +100271570 RPS26P45 HGNC:HGNC:36944 +100271571 RPS26P43 HGNC:HGNC:36675 +100271572 RPS26P46 HGNC:HGNC:35807 +100271574 RPS26P48 HGNC:HGNC:35519 +100271575 RPS26P49 HGNC:HGNC:35514 +100271576 RPS26P51 HGNC:HGNC:36254 +100271577 RPS26P52 HGNC:HGNC:36863 +100271581 RPS27P20 HGNC:HGNC:36333 +100271583 RPS27P26 HGNC:HGNC:36904 +100271584 RPS27P25 HGNC:HGNC:36020 +100271585 RPS27P27 HGNC:HGNC:36043 +100271586 RPS27P28 HGNC:HGNC:36748 +100271587 RPS29P20 HGNC:HGNC:36491 +100271588 RPS29P23 HGNC:HGNC:35779 +100271589 RPS29P24 HGNC:HGNC:35794 +100271590 RPS29P25 HGNC:HGNC:35649 +100271591 RPS29P26 HGNC:HGNC:36490 +100271592 RPS29P27 HGNC:HGNC:35836 +100271593 RPS3AP37 HGNC:HGNC:36691 +100271594 RPS3AP38 HGNC:HGNC:36145 +100271595 RPS3AP41 HGNC:HGNC:37000 +100271596 RPS3AP46 HGNC:HGNC:36338 +100271597 RPS3AP42 HGNC:HGNC:35605 +100271600 RPS3AP51 HGNC:HGNC:35480 +100271601 RPS3AP50 HGNC:HGNC:37018 +100271602 RPL10AP13 HGNC:HGNC:36155 +100271603 RPL13AP24 HGNC:HGNC:36209 +100271604 RPL18AP12 HGNC:HGNC:36991 +100271605 RPL27AP8 HGNC:HGNC:36544 +100271606 RPL37AP9 HGNC:HGNC:36835 +100271607 RPS15AP30 HGNC:HGNC:35495 +100271610 RPL36AP35 HGNC:HGNC:35639 +100271611 RPL36AP53 HGNC:HGNC:36517 +100271612 RPL36AP54 HGNC:HGNC:35831 +100271613 RPS15AP27 HGNC:HGNC:37011 +100271616 RPL23AP58 HGNC:HGNC:36138 +100271617 RPL23AP62 HGNC:HGNC:36276 +100271618 RPL23AP59 HGNC:HGNC:36920 +100271619 RPL23AP70 HGNC:HGNC:36030 +100271620 RPL23AP66 HGNC:HGNC:35940 +100271621 RPL23AP72 HGNC:HGNC:35736 +100271622 RPL23AP67 HGNC:HGNC:36658 +100271623 RPL23AP69 HGNC:HGNC:36625 +100271624 RPL23AP78 HGNC:HGNC:35518 +100271625 RPL23AP73 HGNC:HGNC:36443 +100271626 RPL23AP79 HGNC:HGNC:36226 +100271627 RPL23AP81 HGNC:HGNC:36246 +100271630 RPL35AP26 HGNC:HGNC:36465 +100271631 RPL35AP24 HGNC:HGNC:35544 +100271632 RPL35AP32 HGNC:HGNC:36269 +100271633 RPL35AP25 HGNC:HGNC:36294 +100271634 RPL35AP33 HGNC:HGNC:36950 +100271635 RPL35AP27 HGNC:HGNC:35979 +100271636 RPL35AP35 HGNC:HGNC:36677 +100271637 RPL35AP28 HGNC:HGNC:36480 +100271638 RPL35AP29 HGNC:HGNC:35569 +100271639 RPL35AP30 HGNC:HGNC:36751 +100271640 RPL35AP31 HGNC:HGNC:36284 +100271641 RPL35AP34 HGNC:HGNC:36324 +100271642 RPL36AP38 HGNC:HGNC:35594 +100271643 RPL36AP39 HGNC:HGNC:36074 +100271644 RPL36AP41 HGNC:HGNC:35813 +100271645 RPL36AP42 HGNC:HGNC:36277 +100271646 RPL36AP43 HGNC:HGNC:36791 +100271647 RPL36AP47 HGNC:HGNC:35624 +100271648 RPL36AP50 HGNC:HGNC:36372 +100271649 RPS15AP32 HGNC:HGNC:35879 +100271650 RPS15AP36 HGNC:HGNC:36803 +100271651 RPS15AP37 HGNC:HGNC:36173 +100271652 RPS15AP31 HGNC:HGNC:36960 +100271654 RPS15AP33 HGNC:HGNC:36178 +100271655 RPS15AP38 HGNC:HGNC:36523 +100271656 LOC100271656 - +100271686 DELXP11.3 MIM:300578 +100271687 LNCR3 MIM:612571 +100271688 ANIB9 MIM:612586 +100271689 ANIB10 MIM:612587 +100271690 CRCS8 MIM:612589 +100271691 CRCS10 MIM:612591 +100271692 CRCS11 MIM:612592 +100271693 LNCR4 MIM:612593 +100271694 MS2 MIM:612594 +100271695 MS3 MIM:612595 +100271696 MS4 MIM:612596 +100271697 IDDM23 MIM:612622 +100271698 ADIPQTL4 MIM:612629 +100271700 NONOP2 HGNC:HGNC:42032 +100271702 LINC00940 HGNC:HGNC:48634|Ensembl:ENSG00000235049 +100271703 HAUS1P3 HGNC:HGNC:43762 +100271715 ARHGEF33 HGNC:HGNC:37252|Ensembl:ENSG00000214694|Vega:OTTHUMG00000153540 +100271717 LOC100271717 - +100271718 AD16 MIM:300756 +100271719 PSORS11 MIM:612599 +100271722 LINC00899 HGNC:HGNC:48583 +100271832 LOC100271832 - +100271835 LIMS3-LOC440895 Ensembl:ENSG00000284337 +100271836 SMG1P3 HGNC:HGNC:49860|Ensembl:ENSG00000180747 +100271837 USH1H MIM:612632|HGNC:HGNC:22433 +100271838 IBD26 MIM:612639 +100271842 LOC100271842 - +100271846 ERVV-2 HGNC:HGNC:39051|Ensembl:ENSG00000268964|Vega:OTTHUMG00000182943 +100271849 MEF2B MIM:600661|HGNC:HGNC:6995|Ensembl:ENSG00000213999|Vega:OTTHUMG00000161595 +100271867 MPVQTL1 MIM:612573 +100271868 MPVQTL2 MIM:612574 +100271869 MPVQTL3 MIM:612575 +100271870 RBM22P4 HGNC:HGNC:39697 +100271871 RBM22P2 HGNC:HGNC:39695 +100271873 AIRN MIM:604893|HGNC:HGNC:34515|Ensembl:ENSG00000268257 +100271874 ZNRF2P2 HGNC:HGNC:42793 +100271884 SMARCE1P1 HGNC:HGNC:39731 +100271893 SAMM50P1 HGNC:HGNC:49778 +100271907 LOC100271907 - +100271918 MKI67P1 HGNC:HGNC:49230 +100271921 DEL15Q26QTER MIM:612626 +100271922 BFIS4 MIM:612627 +100271923 FEB10 MIM:612637 +100271924 DFNA59 MIM:612642|HGNC:HGNC:35168 +100271927 RASA4B HGNC:HGNC:35202|Ensembl:ENSG00000170667|Vega:OTTHUMG00000022944 +100272146 NFE2L3P2 HGNC:HGNC:44191 +100272147 CMC4 HGNC:HGNC:35428|Ensembl:ENSG00000182712|Vega:OTTHUMG00000158504 +100272169 L1RE4 HGNC:HGNC:37056 +100272205 TATDN2P2 HGNC:HGNC:39255 +100272217 LOC100272217 - +100272220 RPAP2P1 HGNC:HGNC:45125 +100272224 UAQTL3 MIM:612670 +100272225 UAQTL4 MIM:612671 +100272228 LINC00894 HGNC:HGNC:48579|Ensembl:ENSG00000235703 +100286746 LOC100286746 - +100286836 OS6 MIM:612401 +100286844 BCDIN3D-AS1 HGNC:HGNC:44113|Ensembl:ENSG00000258057 +100286895 LOC100286895 - +100286906 LOC100286906 - +100286918 NDUFS5P2 HGNC:HGNC:44040 +100286922 LOC100286922 Ensembl:ENSG00000178836 +100286925 LOC100286925 - +100286929 NMD3P2 HGNC:HGNC:37820 +100286938 VPS13A-AS1 HGNC:HGNC:44167|Ensembl:ENSG00000232998 +100286942 LOC100286942 - +100286945 LOC100286945 - +100286946 LOC100286946 - +100286948 APOOP1 HGNC:HGNC:48739 +100286954 HSPE1P12 HGNC:HGNC:49331 +100286958 LOC100286958 - +100286962 LOC100286962 - +100286963 DEFB109C HGNC:HGNC:43844 +100286964 TSPY23P HGNC:HGNC:38594 +100286965 CBX3P8 HGNC:HGNC:42880 +100286971 UBDP1 HGNC:HGNC:18796 +100286973 LOC100286973 - +100286979 ANAPC1P1 HGNC:HGNC:44150|Ensembl:ENSG00000233673 +100286986 LOC100286986 - +100286992 LOC100286992 - +100286996 TSPY22P HGNC:HGNC:38522 +100286997 LOC100286997 - +100287010 LOC100287010 - +100287013 FAM86KP HGNC:HGNC:44098 +100287014 LOC100287014 - +100287015 LOC100287015 Ensembl:ENSG00000246089 +100287016 DSTNP3 HGNC:HGNC:34547 +100287026 TTTY25P HGNC:HGNC:38524 +100287028 LOC100287028 - +100287029 DDX11L10 HGNC:HGNC:14125|Ensembl:ENSG00000233614 +100287033 LOC100287033 - +100287036 LOC100287036 - +100287042 LOC100287042 Ensembl:ENSG00000263843 +100287045 FAM90A26 HGNC:HGNC:43746 +100287046 LOC100287046 - +100287049 LOC100287049 - +100287055 TSPY21P HGNC:HGNC:38101 +100287063 GEMIN2P2 HGNC:HGNC:49562 +100287066 DEFB131D HGNC:HGNC:38061 +100287067 MTCO1P51 HGNC:HGNC:52116 +100287072 LOC100287072 - +100287074 LOC100287074 - +100287082 GACAT2 MIM:616131|HGNC:HGNC:50516|Ensembl:ENSG00000265962 +100287083 DEFT1P2 HGNC:HGNC:33599|Ensembl:ENSG00000232039 +100287084 ZNF72P MIM:194546|HGNC:HGNC:13142 +100287085 OCIAD2P1 HGNC:HGNC:31827 +100287087 H3F3BP1 HGNC:HGNC:42030 +100287091 ATP5LP5 HGNC:HGNC:38167 +100287098 TONSL-AS1 HGNC:HGNC:51556 +100287102 DDX11L1 HGNC:HGNC:37102|Ensembl:ENSG00000223972 +100287114 LINC00421 HGNC:HGNC:42755|Ensembl:ENSG00000236834 +100287128 IGHV1OR15-2 HGNC:HGNC:5564|IMGT/GENE-DB:IGHV1/OR15-2 +100287136 CICP28 HGNC:HGNC:48832 +100287140 HSPD1P14 HGNC:HGNC:35143 +100287144 USP17L10 HGNC:HGNC:44438|Ensembl:ENSG00000231396|Vega:OTTHUMG00000160160 +100287148 LOC100287148 - +100287157 LOC100287157 - +100287167 TTTY29P HGNC:HGNC:38547 +100287171 WASHC1 MIM:613632|HGNC:HGNC:24361|Ensembl:ENSG00000181404|Vega:OTTHUMG00000019420 +100287173 UBE2V1P5 HGNC:HGNC:44888 +100287175 LOC100287175 Ensembl:ENSG00000172366 +100287177 EML2-AS1 HGNC:HGNC:48331|Ensembl:ENSG00000267757 +100287178 USP17L11 HGNC:HGNC:44439|Ensembl:ENSG00000233136|Vega:OTTHUMG00000160162 +100287183 NUTF2P8 HGNC:HGNC:50457 +100287188 LOC100287188 - +100287189 LOC100287189 - +100287191 HNRNPA1P47 HGNC:HGNC:48777 +100287193 ISCA2P1 HGNC:HGNC:38022 +100287200 RAB9AP1 HGNC:HGNC:38104 +100287205 USP17L12 HGNC:HGNC:44440|Ensembl:ENSG00000227551|Vega:OTTHUMG00000160148 +100287212 LOC100287212 - +100287215 UBL5P2 HGNC:HGNC:44640 +100287216 SH3RF3-AS1 HGNC:HGNC:44168 +100287225 LINC01630 HGNC:HGNC:52295|Ensembl:ENSG00000227115 +100287226 ZNF729 HGNC:HGNC:32464|Ensembl:ENSG00000196350|Vega:OTTHUMG00000182938 +100287227 TIPARP-AS1 HGNC:HGNC:41028 +100287229 BRD7P4 HGNC:HGNC:37630 +100287234 RAB9AP5 HGNC:HGNC:38109 +100287238 USP17L13 HGNC:HGNC:44441|Ensembl:ENSG00000232399|Vega:OTTHUMG00000160152 +100287243 LOC100287243 - +100287261 CSPG4P3Y HGNC:HGNC:38111 +100287266 HNRNPA1P42 HGNC:HGNC:48771 +100287270 USP17L14P HGNC:HGNC:44442 +100287272 USP8P1 HGNC:HGNC:13987 +100287275 PCOTHP1 HGNC:HGNC:39840 +100287279 UBE2V1P6 HGNC:HGNC:44889 +100287284 MANSC4 HGNC:HGNC:40023|Ensembl:ENSG00000205693|Vega:OTTHUMG00000169216 +100287290 LOC100287290 - +100287294 LOC100287294 - +100287296 LINC00265-2P HGNC:HGNC:38523 +100287302 USP17L16P HGNC:HGNC:44444 +100287309 LOC100287309 - +100287314 LINC00941 HGNC:HGNC:48635|Ensembl:ENSG00000235884 +100287325 KRT8P37 HGNC:HGNC:39871 +100287327 USP17L17 HGNC:HGNC:44445|Ensembl:ENSG00000249104|Vega:OTTHUMG00000160158 +100287329 LOC100287329 - +100287335 LOC100287335 - +100287345 VENTXP2 HGNC:HGNC:30901 +100287355 LOC100287355 - +100287357 LOC100287357 - +100287361 LOC100287361 - +100287362 PRSS46 HGNC:HGNC:37325|Ensembl:ENSG00000261603|Vega:OTTHUMG00000177121 +100287364 USP17L18 HGNC:HGNC:44446|Ensembl:ENSG00000250844|Vega:OTTHUMG00000160153 +100287366 OSTM1-AS1 HGNC:HGNC:43666|Ensembl:ENSG00000225174 +100287369 HSPE1P4 HGNC:HGNC:49323 +100287372 IGHV3OR16-13 HGNC:HGNC:5637|IMGT/GENE-DB:IGHV3/OR16-13 +100287387 LOC100287387 - +100287388 LIN28AP2 HGNC:HGNC:38056 +100287399 POTEB2 HGNC:HGNC:48327|Ensembl:ENSG00000230031|Vega:OTTHUMG00000185829 +100287402 LOC100287402 - +100287404 USP17L19 HGNC:HGNC:44447|Ensembl:ENSG00000248920|Vega:OTTHUMG00000160146 +100287413 LOC100287413 Ensembl:ENSG00000166840 +100287419 CDK8P2 HGNC:HGNC:52296 +100287425 LOC100287425 - +100287427 LOC100287427 - +100287430 LOC100287430 - +100287441 USP17L20 HGNC:HGNC:44448|Ensembl:ENSG00000250745|Vega:OTTHUMG00000160150 +100287453 LOC100287453 - +100287461 MTND1P8 HGNC:HGNC:42100 +100287463 BOLA3P2 HGNC:HGNC:51441 +100287467 LOC100287467 - +100287470 LINC00265-3P HGNC:HGNC:38536 +100287472 NPM1P31 HGNC:HGNC:45210 +100287477 LOC100287477 - +100287478 USP17L21 HGNC:HGNC:44449|Ensembl:ENSG00000249811|Vega:OTTHUMG00000160149 +100287482 SMKR1 HGNC:HGNC:43561|Ensembl:ENSG00000240204|Vega:OTTHUMG00000157696 +100287483 ELOCP28 HGNC:HGNC:49169 +100287485 LOC100287485 - +100287489 LOC100287489 - +100287495 GCSHP4 HGNC:HGNC:43930 +100287497 LOC100287497 - +100287498 LOC100287498 - +100287502 CSPG4P4Y HGNC:HGNC:38535 +100287505 BRWD1P2 HGNC:HGNC:51529 +100287512 RPS3AP53 HGNC:HGNC:44500 +100287513 USP17L22 HGNC:HGNC:44450|Ensembl:ENSG00000248933|Vega:OTTHUMG00000160159 +100287520 GLYATL1P3 HGNC:HGNC:37865 +100287523 LOC100287523 - +100287528 IGLL4P HGNC:HGNC:38475 +100287539 LOC100287539 - +100287542 RAB9AP2 HGNC:HGNC:38106 +100287544 LOC100287544 - +100287551 HSPA8P8 HGNC:HGNC:44923 +100287559 ADPGK-AS1 HGNC:HGNC:44144|Ensembl:ENSG00000260898 +100287567 TRMT112P7 HGNC:HGNC:44026 +100287569 LINC00173 HGNC:HGNC:33791|Ensembl:ENSG00000196668 +100287573 TOMM22P6 HGNC:HGNC:38742 +100287577 RAB9AP3 HGNC:HGNC:38107 +100287579 ELOCP22 HGNC:HGNC:38158 +100287591 MTND1P22 HGNC:HGNC:42093 +100287592 LINC02106 HGNC:HGNC:52961|Ensembl:ENSG00000251573 +100287596 DDX11L5 HGNC:HGNC:37106 +100287603 SSXP10 HGNC:HGNC:30638 +100287606 TTTY28P HGNC:HGNC:38534 +100287610 LOC100287610 - +100287613 LOC100287613 - +100287614 LOC100287614 - +100287616 LOXL1-AS1 MIM:616800|HGNC:HGNC:44169|Ensembl:ENSG00000261801 +100287625 SUPT4H1P2 HGNC:HGNC:50823 +100287630 PSAT1P4 HGNC:HGNC:43990 +100287632 LOC100287632 - +100287635 KRT18P62 HGNC:HGNC:48889 +100287639 MTHFD2P1 HGNC:HGNC:48859|Ensembl:ENSG00000244681 +100287647 PCMTD1P2 HGNC:HGNC:38805 +100287653 LOC100287653 - +100287680 SUB1P2 HGNC:HGNC:43992 +100287682 EXTL2P1 HGNC:HGNC:3517 +100287692 ELOCP24 HGNC:HGNC:38160 +100287704 LOC100287704 Ensembl:ENSG00000230000 +100287708 CCDC58P2 HGNC:HGNC:45025 +100287715 KRTAP9-12P HGNC:HGNC:48873 +100287718 ANKRD66 HGNC:HGNC:44669|Ensembl:ENSG00000230062|Vega:OTTHUMG00000014791 +100287722 AP4B1-AS1 HGNC:HGNC:44114|Ensembl:ENSG00000226167 +100287725 GAPDHP76 HGNC:HGNC:50649 +100287728 SMIM10L2B-AS1 HGNC:HGNC:53137 +100287735 TTTY13B HGNC:HGNC:38596 +100287745 MTATP6P2 HGNC:HGNC:44576 +100287754 LOC100287754 - +100287755 ATP5G1P4 HGNC:HGNC:39507 +100287757 LOC100287757 - +100287765 LINC00630 HGNC:HGNC:44263|Ensembl:ENSG00000223546 +100287768 COX6A1P3 HGNC:HGNC:37633 +100287769 RBMY1GP HGNC:HGNC:9915 +100287778 ELOCP20 HGNC:HGNC:38156 +100287785 LINC00266-2P HGNC:HGNC:38529 +100287792 LOC100287792 Ensembl:ENSG00000204117 +100287808 LOC100287808 Ensembl:ENSG00000277182 +100287814 LINC00582 HGNC:HGNC:43842|Ensembl:ENSG00000229228 +100287817 NDUFS5P4 HGNC:HGNC:44042 +100287818 TTTY26P HGNC:HGNC:38528 +100287822 SETP10 HGNC:HGNC:42929 +100287825 LOC100287825 - +100287834 LOC100287834 - +100287837 LOC100287837 - +100287840 LOC100287840 - +100287844 TTTY30P HGNC:HGNC:38604 +100287845 GOLGA6L16P HGNC:HGNC:38117 +100287846 LOC100287846 - +100287852 LOC100287852 - +100287856 LOC100287856 - +100287868 NUTF2P7 HGNC:HGNC:50458 +100287874 TTTY27P HGNC:HGNC:38527 +100287879 LINC00994 HGNC:HGNC:48949|Ensembl:ENSG00000189196 +100287880 NDUFA4P2 HGNC:HGNC:31362 +100287887 RPL13AP25 HGNC:HGNC:36981 +100287895 NARSP2 HGNC:HGNC:50481 +100287896 LOC100287896 - +100287898 TTC34 HGNC:HGNC:34297|Ensembl:ENSG00000215912 +100287900 GM2AP2 HGNC:HGNC:38002 +100287902 LGALS8-AS1 HGNC:HGNC:40340|Ensembl:ENSG00000223776 +100287905 TTTY31P HGNC:HGNC:38711 +100287908 ZNF519P2 HGNC:HGNC:50786 +100287912 LOC100287912 - +100287919 VN1R30P HGNC:HGNC:37350 +100287928 LOC100287928 - +100287932 TIMM23 MIM:605034|HGNC:HGNC:17312|Ensembl:ENSG00000265354|Vega:OTTHUMG00000188299 +100287934 LOC100287934 - +100287941 TTTY24P HGNC:HGNC:38521 +100287944 LOC100287944 Ensembl:ENSG00000257545 +100287948 LINC01699 HGNC:HGNC:52487|Ensembl:ENSG00000179452 +100287951 LOC100287951 - +100287960 HIGD1AP10 HGNC:HGNC:43005 +100287964 ATP5LP7 HGNC:HGNC:38169 +100287965 LOC100287965 - +100287966 LOC100287966 - +100287979 TTTY13C HGNC:HGNC:38613 +100287985 LOC100287985 - +100288001 LOC100288001 - +100288008 PRR13P4 HGNC:HGNC:50617 +100288010 LOC100288010 - +100288013 NDUFA5P12 HGNC:HGNC:48854 +100288016 LOC100288016 - +100288022 VN1R33P HGNC:HGNC:37353 +100288025 DYZ1L2 - +100288028 LOC100288028 - +100288031 LOC100288031 - +100288035 NDUFA5P3 HGNC:HGNC:48845 +100288038 HNRNPA1P28 HGNC:HGNC:39546 +100288042 ZNF519P3 HGNC:HGNC:50787 +100288053 DYZ1L3 - +100288069 LOC100288069 - +100288072 SDR42E2 HGNC:HGNC:35414 +100288073 LOC100288073 - +100288077 WTAPP1 HGNC:HGNC:44115|Ensembl:ENSG00000255282 +100288079 GS1-279B7.1 Ensembl:ENSG00000261024 +100288083 CICP22 HGNC:HGNC:48838 +100288085 DYZ1L5 - +100288093 LOC100288093 - +100288097 LOC100288097 - +100288111 BOLA3P1 HGNC:HGNC:51440 +100288112 OR11J7P HGNC:HGNC:38589 +100288122 LDLRAD4-AS1 HGNC:HGNC:48592|Ensembl:ENSG00000267690 +100288123 LOC100288123 Ensembl:ENSG00000267244 +100288124 DYZ1L8 - +100288125 LOC100288125 - +100288129 ADI1P3 HGNC:HGNC:52341 +100288130 MTCL1P1 HGNC:HGNC:42040 +100288142 NBPF20 MIM:614007|HGNC:HGNC:32000|Ensembl:ENSG00000162825|Vega:OTTHUMG00000042439 +100288146 LOC100288146 - +100288148 OR11J6P HGNC:HGNC:38588 +100288149 NDUFS5P3 HGNC:HGNC:44041 +100288151 LOC100288151 - +100288152 SLC9A3-AS1 HGNC:HGNC:40550 +100288157 DYZ1L9 - +100288162 LOC100288162 - +100288165 HMGN2P15 HGNC:HGNC:39020 +100288170 UBE2V1P15 HGNC:HGNC:52414 +100288172 LOC100288172 - +100288173 TRMT112P4 HGNC:HGNC:44023 +100288175 LOC100288175 Ensembl:ENSG00000217801 +100288179 TSEN15P1 HGNC:HGNC:43962 +100288181 LOC100288181 Ensembl:ENSG00000253741 +100288185 PPIAP1 HGNC:HGNC:9254 +100288188 DYZ1L10 - +100288192 LOC100288192 - +100288195 VN1R104P HGNC:HGNC:37427 +100288198 HMGN3-AS1 HGNC:HGNC:48984|Ensembl:ENSG00000270362 +100288203 LOC100288203 - +100288208 LOC100288208 - +100288211 LOC100288211 - +100288220 DYZ1L11 - +100288222 ATP5G1P8 HGNC:HGNC:39511 +100288227 MTND1P27 HGNC:HGNC:42076 +100288233 LOC100288233 - +100288235 HSPE1P10 HGNC:HGNC:49329 +100288241 LOC100288241 - +100288248 ZNHIT1P1 HGNC:HGNC:44474 +100288250 ISCA1P5 HGNC:HGNC:38026 +100288252 RPL10P1 HGNC:HGNC:10300 +100288254 LOC100288254 - +100288259 DYZ1L12 - +100288264 VN1R105P HGNC:HGNC:37428 +100288283 HNRNPA1P61 HGNC:HGNC:48791 +100288287 KRTAP22-2 HGNC:HGNC:37091|Ensembl:ENSG00000206106|Vega:OTTHUMG00000065630 +100288293 DYZ1L13 - +100288298 GCSHP2 HGNC:HGNC:43927 +100288307 USMG5P1 HGNC:HGNC:31716 +100288319 AK3P5 HGNC:HGNC:39064 +100288323 KRTAP21-3 HGNC:HGNC:34216|Ensembl:ENSG00000231068|Vega:OTTHUMG00000125533 +100288329 DYZ1L14 - +100288330 H2AFZP5 HGNC:HGNC:38018 +100288332 NPIPA5 HGNC:HGNC:41980|Ensembl:ENSG00000183793|Vega:OTTHUMG00000166305 +100288337 NDUFB5P1 HGNC:HGNC:52267 +100288339 NDUFA5P6 HGNC:HGNC:48848 +100288343 SLC25A14P1 HGNC:HGNC:43856 +100288346 NCAM1-AS1 HGNC:HGNC:48675|Ensembl:ENSG00000227487 +100288363 DYZ1L15 - +100288365 LOC100288365 - +100288367 LOC100288367 - +100288378 LRRC34P1 HGNC:HGNC:49887 +100288379 LOC100288379 - +100288380 ULK4P2 HGNC:HGNC:15776|Ensembl:ENSG00000260128 +100288385 LOC100288385 - +100288392 LOC100288392 - +100288397 RAB9AP4 HGNC:HGNC:38108 +100288402 DYZ1L17 - +100288405 SFTPA3P HGNC:HGNC:10800 +100288413 ERVMER34-1 HGNC:HGNC:42970|Ensembl:ENSG00000226887|Vega:OTTHUMG00000150366 +100288416 LOC100288416 - +100288420 NDUFB4P3 HGNC:HGNC:45251 +100288425 EIF1P2 HGNC:HGNC:49615 +100288428 LMCD1-AS1 HGNC:HGNC:44477|Ensembl:ENSG00000227110 +100288430 LOC100288430 - +100288432 IL10RB-AS1 HGNC:HGNC:44303 +100288435 DYZ1L18 - +100288436 SLC4A1APP1 HGNC:HGNC:49811 +100288437 LOC100288437 - +100288440 COX5BP5 HGNC:HGNC:2274 +100288451 RBBP4P5 HGNC:HGNC:42372 +100288463 CUL1P1 HGNC:HGNC:49567 +100288465 FAM197Y10 HGNC:HGNC:37627 +100288468 DYZ1L21 - +100288470 REXO1L11P HGNC:HGNC:44434 +100288482 LOC100288482 - +100288483 HSBP1P2 HGNC:HGNC:37300 +100288484 LOC100288484 - +100288485 MTRNR2L7 HGNC:HGNC:37164|Ensembl:ENSG00000256892|Vega:OTTHUMG00000184979 +100288486 DDX11L9 HGNC:HGNC:37109|Ensembl:ENSG00000248472 +100288493 ELOCP5 HGNC:HGNC:38140 +100288499 DYZ1L22 - +100288500 REXO1L10P HGNC:HGNC:44433 +100288503 SMIM12P1 HGNC:HGNC:51598 +100288506 PNPT1P1 HGNC:HGNC:44468 +100288510 LOC100288510 - +100288513 TUBB3P1 HGNC:HGNC:42339 +100288517 ISCA1P2 HGNC:HGNC:38023 +100288520 USP17L15 HGNC:HGNC:44443|Ensembl:ENSG00000223569 +100288524 WI2-2373I1.2 Ensembl:ENSG00000248767 +100288526 DYZ1L24 - +100288527 REXO1L2P HGNC:HGNC:32239 +100288533 LOC100288533 - +100288540 POM121B HGNC:HGNC:34004 +100288542 LOC100288542 - +100288543 FOLR3P1 HGNC:HGNC:38074 +100288558 LOC100288558 - +100288560 LOC100288560 - +100288561 DYZ1L25 - +100288562 LOC100288562 - +100288563 HMGB3P23 HGNC:HGNC:39315 +100288570 LOC100288570 Ensembl:ENSG00000184115 +100288580 ACTR3P1 HGNC:HGNC:31820 +100288584 CCDC34P1 HGNC:HGNC:44008 +100288590 LOC100288590 - +100288595 DYZ1L26 - +100288596 SNRPCP1 HGNC:HGNC:49816 +100288610 LINC00268-2P HGNC:HGNC:37771 +100288613 UBE2NP1 HGNC:HGNC:20337 +100288615 WHAMMP1 HGNC:HGNC:32361 +100288628 LOC100288628 - +100288637 LOC100288637 Ensembl:ENSG00000187951 +100288654 NDUFB4P1 HGNC:HGNC:45248 +100288656 LOC100288656 - +100288659 ZNF317P1 HGNC:HGNC:31062 +100288661 SUB1P4 HGNC:HGNC:43994 +100288663 LOC100288663 - +100288666 LOC100288666 - +100288667 CICP7 HGNC:HGNC:37756 +100288683 LOC100288683 - +100288687 DUX4 MIM:606009|HGNC:HGNC:50800|Ensembl:ENSG00000260596|Vega:OTTHUMG00000175568 +100288690 FAM21FP HGNC:HGNC:45011 +100288691 HMGN2P8 HGNC:HGNC:31662 +100288695 LIMS4 HGNC:HGNC:39941|Ensembl:ENSG00000256671|Vega:OTTHUMG00000169984 +100288702 ARL6IP1P1 HGNC:HGNC:23178 +100288703 LOC100288703 - +100288711 DUX4L9 MIM:615581|HGNC:HGNC:33855 +100288712 LOC100288712 - +100288713 PMS2P10 HGNC:HGNC:9124 +100288724 LOC100288724 - +100288726 HSPE1P20 HGNC:HGNC:49339 +100288728 LOC100288728 - +100288730 PAN3-AS1 HGNC:HGNC:39932 +100288739 SPCS2P3 HGNC:HGNC:45236 +100288742 HIST1H2BPS1 HGNC:HGNC:18719 +100288748 LOC100288748 Ensembl:ENSG00000261437 +100288757 SUMO2P4 HGNC:HGNC:39014 +100288763 LOC100288763 - +100288771 LOC100288771 - +100288772 CCT7P2 HGNC:HGNC:35134 +100288774 AGGF1P10 HGNC:HGNC:51747 +100288778 LOC100288778 Ensembl:ENSG00000226210 +100288785 UQCRBP3 HGNC:HGNC:39033 +100288788 LOC100288788 - +100288797 TMEM239 HGNC:HGNC:40044|Ensembl:ENSG00000198326|Vega:OTTHUMG00000031713 +100288798 LOC100288798 - +100288801 FRG2C HGNC:HGNC:33626|Ensembl:ENSG00000172969|Vega:OTTHUMG00000158963 +100288802 RPL23AP93 HGNC:HGNC:51628 +100288803 LOC100288803 - +100288805 HYDIN2 MIM:610813|HGNC:HGNC:33129 +100288806 CDC27P8 HGNC:HGNC:51758 +100288814 CLDN34 HGNC:HGNC:51259|Ensembl:ENSG00000234469|Vega:OTTHUMG00000189259 +100288825 TTC39CP1 HGNC:HGNC:44019 +100288827 CYP4F25P HGNC:HGNC:39949 +100288831 SRGAP3-AS3 HGNC:HGNC:40900|Ensembl:ENSG00000227929 +100288841 RBPJP5 HGNC:HGNC:37485 +100288842 LOC100288842 - +100288843 NAPGP1 HGNC:HGNC:45165 +100288844 LOC100288844 - +100288846 LOC100288846 Ensembl:ENSG00000258940 +100288853 LOC100288853 - +100288861 TRMT112P1 HGNC:HGNC:44020 +100288866 LOC100288866 Ensembl:ENSG00000249906 +100288868 KRT18P63 HGNC:HGNC:48890 +100288870 ERLEC1P1 HGNC:HGNC:38012 +100288885 DYNLL1P6 HGNC:HGNC:49657 +100288892 COX6CP4 HGNC:HGNC:32374 +100288897 FAR2P3 HGNC:HGNC:49285 +100288904 CICP11 HGNC:HGNC:37903 +100288911 LOC100288911 - +100288914 LOC100288914 - +100288929 LOC100288929 - +100288935 LOC100288935 - +100288948 BRD7P1 HGNC:HGNC:19923 +100288950 MTND1P25 HGNC:HGNC:42091 +100288960 PRSS43 HGNC:HGNC:37323 +100288962 LOC100288962 - +100288964 FABP5P5 HGNC:HGNC:31068 +100288966 LOC100288966 Ensembl:ENSG00000277630 +100288971 ADI1P2 HGNC:HGNC:52340 +100288974 BMS1P21 HGNC:HGNC:51604 +100288978 LOC100288978 - +100288979 DCAF13P2 HGNC:HGNC:43867 +100288984 MTND1P3 HGNC:HGNC:42052 +100288998 MTND1P15 HGNC:HGNC:42064 +100289004 LOC100289004 - +100289017 MOXD2P HGNC:HGNC:33605|Ensembl:ENSG00000240268 +100289019 SLC25A25-AS1 HGNC:HGNC:27844 +100289026 LOC100289026 - +100289027 CDK2AP2P1 HGNC:HGNC:38492 +100289028 BNIP3P4 HGNC:HGNC:39657 +100289034 RPL23AP88 HGNC:HGNC:51579 +100289037 LOC100289037 - +100289047 LOC100289047 - +100289051 CYB5AP5 HGNC:HGNC:2576 +100289059 TMEM261P1 HGNC:HGNC:49128 +100289060 LOC100289060 - +100289061 LOC100289061 - +100289085 LOC100289085 - +100289087 TSPY10 HGNC:HGNC:37473|Ensembl:ENSG00000236424|Vega:OTTHUMG00000041524 +100289091 LOC100289091 - +100289092 ATP2A1-AS1 HGNC:HGNC:51370|Ensembl:ENSG00000260442 +100289095 BCL2L12P1 HGNC:HGNC:51327 +100289097 FRG1CP HGNC:HGNC:51762|Ensembl:ENSG00000282826 +100289098 GS1-124K5.4 Ensembl:ENSG00000237310 +100289099 RPL30P16 HGNC:HGNC:48340 +100289102 EIF4A1P8 HGNC:HGNC:37927 +100289117 LOC100289117 - +100289118 LOC100289118 - +100289124 FAM27E2 HGNC:HGNC:32013 +100289131 COX6CP6 HGNC:HGNC:47037 +100289133 KRT8P32 HGNC:HGNC:39866 +100289137 FAM95C HGNC:HGNC:45272|Ensembl:ENSG00000273036 +100289141 LOC100289141 - +100289143 LOC100289143 - +100289150 FAM197Y5 HGNC:HGNC:37467|Ensembl:ENSG00000225516 +100289158 HMGB3P13 HGNC:HGNC:39305 +100289170 COX20P2 HGNC:HGNC:43772 +100289178 GNG12-AS1 MIM:615406|HGNC:HGNC:43938|Ensembl:ENSG00000232284 +100289184 LOC100289184 - +100289185 LOC100289185 - +100289186 SDHDP1 HGNC:HGNC:10684 +100289187 TMEM225B HGNC:HGNC:53075|Ensembl:ENSG00000244219|Vega:OTTHUMG00000156636 +100289188 FAM197Y4 HGNC:HGNC:37466 +100289191 HMGN3P1 HGNC:HGNC:39206 +100289193 LOC100289193 - +100289194 LOC100289194 - +100289196 LOC100289196 - +100289206 LOC100289206 - +100289211 LINC00624 HGNC:HGNC:44254|Ensembl:ENSG00000278811 +100289220 LTV1P1 HGNC:HGNC:44049 +100289230 LOC100289230 - +100289237 CEP164P1 HGNC:HGNC:44988 +100289238 LOC100289238 - +100289244 LOC100289244 - +100289255 LINC00675 HGNC:HGNC:44356|Ensembl:ENSG00000263429|Vega:OTTHUMG00000132847 +100289259 ZFYVE9P1 HGNC:HGNC:33359 +100289264 RPL7P60 HGNC:HGNC:49216 +100289265 FAM197Y1 HGNC:HGNC:37464 +100289274 DNAJC3-AS1 HGNC:HGNC:39808|Ensembl:ENSG00000247400 +100289279 LOC100289279 Ensembl:ENSG00000283378|Vega:OTTHUMG00000191808 +100289280 CUBNP2 HGNC:HGNC:44984 +100289286 HNRNPA1P58 HGNC:HGNC:48788 +100289295 NUP58P1 HGNC:HGNC:44052 +100289300 HIGD1AP5 HGNC:HGNC:42999 +100289303 LOC100289303 - +100289315 LOC100289315 - +100289319 KRT8P43 HGNC:HGNC:39877 +100289320 LOC100289320 - +100289333 LOC100289333 - +100289341 MAN1B1-AS1 HGNC:HGNC:48715|Ensembl:ENSG00000268996 +100289350 LOC100289350 - +100289351 LOC100289351 - +100289360 LOC100289360 - +100289361 LOC100289361 Ensembl:ENSG00000268129 +100289371 MTCO3P22 HGNC:HGNC:52125 +100289373 UBAC2-AS1 HGNC:HGNC:42502|Ensembl:ENSG00000228889 +100289380 PTP4A1P5 HGNC:HGNC:41932 +100289381 LOC100289381 - +100289383 CICP25 HGNC:HGNC:48837 +100289388 KCTD21-AS1 HGNC:HGNC:48674|Ensembl:ENSG00000246174 +100289404 MTCO2P22 HGNC:HGNC:52151 +100289410 MCF2L-AS1 HGNC:HGNC:39825 +100289414 PHBP9 HGNC:HGNC:39288 +100289416 LOC100289416 - +100289419 CTF2P HGNC:HGNC:33173 +100289442 LOC100289442 - +100289448 REXO1L12P HGNC:HGNC:44435 +100289450 SLC7A15P HGNC:HGNC:32724 +100289455 LOC100289455 - +100289462 DEFB4B HGNC:HGNC:30193|Ensembl:ENSG00000177257|Vega:OTTHUMG00000143857 +100289470 LOC100289470 - +100289473 LOC100289473 Ensembl:ENSG00000232528 +100289475 LDHBP1 HGNC:HGNC:6542 +100289479 LOC100289479 - +100289489 MINOS1P2 HGNC:HGNC:44092 +100289495 LOC100289495 - +100289500 LOC100289500 - +100289501 FTLP11 HGNC:HGNC:37960 +100289509 KCNIP2-AS1 HGNC:HGNC:48680|Ensembl:ENSG00000226009 +100289511 LOC100289511 - +100289518 LOC100289518 - +100289543 LOC100289543 - +100289545 HIST1H3PS1 HGNC:HGNC:18982 +100289561 LOC100289561 - +100289564 SNRPCP18 HGNC:HGNC:49833 +100289568 LOC100289568 - +100289569 LOC100289569 - +100289574 HERC2P4 HGNC:HGNC:4872 +100289579 NDUFA5P9 HGNC:HGNC:48851 +100289580 LOC100289580 - +100289581 DUX4L13 HGNC:HGNC:38672 +100289584 NPM1P40 HGNC:HGNC:45219 +100289605 HIGD1AP15 HGNC:HGNC:43010 +100289607 HSPE1P22 HGNC:HGNC:49341 +100289619 TRIAP1P1 HGNC:HGNC:31659 +100289623 UBE2V1P14 HGNC:HGNC:52412 +100289635 ZNF605 HGNC:HGNC:28068|Ensembl:ENSG00000196458|Vega:OTTHUMG00000167934 +100289640 PPATP1 HGNC:HGNC:9239 +100289643 HSPA8P16 HGNC:HGNC:44931 +100289644 PRR13P7 HGNC:HGNC:50620 +100289650 PSG8-AS1 HGNC:HGNC:52550|Ensembl:ENSG00000225877 +100289656 LOC100289656 Ensembl:ENSG00000232431 +100289662 COX6B1P5 HGNC:HGNC:37675 +100289663 STMN1P2 HGNC:HGNC:44063 +100289667 POLR3KP1 HGNC:HGNC:39577 +100289673 LINC01848 HGNC:HGNC:52663 +100289678 ZNF783 HGNC:HGNC:27222|Ensembl:ENSG00000204946|Vega:OTTHUMG00000158969 +100289682 HMGN2P13 HGNC:HGNC:33557 +100289683 ERVH-3 HGNC:HGNC:39055 +100290036 LOC100290036 - +100290481 CYAT1 - +100291105 LOC100291105 - +100291628 LOC100291628 - +100292290 HSPE1P8 HGNC:HGNC:49326 +100292680 LINC00942 HGNC:HGNC:48636 +100292922 LOC100292922 - +100293090 MTND4P12 HGNC:HGNC:42199 +100293516 ZNF587B HGNC:HGNC:37142|Ensembl:ENSG00000269343|Vega:OTTHUMG00000183479 +100293534 C4B_2 HGNC:HGNC:42398 +100293612 LOC100293612 - +100293948 ATG12P2 HGNC:HGNC:38605 +100294145 LOC100294145 - +100294160 LOC100294160 - +100294188 LOC100294188 - +100294316 LOC100294316 - +100294336 LOC100294336 - +100294362 LOC100294362 Ensembl:ENSG00000263069 +100294713 LOC100294713 - +100294715 BOP MIM:612691 +100294716 MYP15 MIM:612717|HGNC:HGNC:35440 +100294717 BMND13 MIM:612727 +100294718 BMND14 MIM:612728 +100294719 LBMQTL1 MIM:612729 +100294720 NHEG1 Ensembl:ENSG00000225391 +100301516 LOC100301516 - +100301521 LOC100301521 - +100301522 CELIAC7 MIM:612005 +100301523 STQTL12 MIM:612224 +100301525 DUH2 MIM:612715 +100301526 STQTL17 MIM:612737 +100301527 SYNSTH MIM:612759 +100301572 PRBNS MIM:261800 +100301990 LOC100301990 - +100302058 LKMCD MIM:300660 +100302059 IBD27 MIM:612796 +100302090 DDX11L8 HGNC:HGNC:37101 +100302111 MIR1184-1 HGNC:HGNC:35265|Ensembl:ENSG00000221533|miRBase:MI0006277 +100302112 MIR1284 HGNC:HGNC:35362|Ensembl:ENSG00000221264|miRBase:MI0006431 +100302113 MIR1200 HGNC:HGNC:35266|Ensembl:ENSG00000221325|miRBase:MI0006332 +100302114 MIR513C HGNC:HGNC:33934|Ensembl:ENSG00000216171|miRBase:MI0006649 +100302115 MIR1468 HGNC:HGNC:35250|Ensembl:ENSG00000222532|miRBase:MI0003782 +100302116 MIR1265 HGNC:HGNC:35332|Ensembl:ENSG00000221371|miRBase:MI0006401 +100302117 MIR320B1 HGNC:HGNC:35247|Ensembl:ENSG00000211543|miRBase:MI0003776 +100302118 MIR1286 HGNC:HGNC:35279|Ensembl:ENSG00000221039|miRBase:MI0006348 +100302119 MIR1538 HGNC:HGNC:35382|Ensembl:ENSG00000223109|miRBase:MI0007259 +100302121 MIR1276 HGNC:HGNC:35347|Ensembl:ENSG00000221634|miRBase:MI0006416 +100302122 MIR1183 HGNC:HGNC:35264|Ensembl:ENSG00000221783|miRBase:MI0006276 +100302123 MIR1275 HGNC:HGNC:35346|Ensembl:ENSG00000221697|miRBase:MI0006415 +100302124 MIR1288 HGNC:HGNC:35363|Ensembl:ENSG00000221355|miRBase:MI0006432 +100302125 MIR1289-1 HGNC:HGNC:35281|Ensembl:ENSG00000221763|miRBase:MI0006350 +100302126 MIR1471 HGNC:HGNC:35380|Ensembl:ENSG00000222246|miRBase:MI0007076 +100302127 MIR1470 HGNC:HGNC:35379|Ensembl:ENSG00000269782|miRBase:MI0007075 +100302128 MIR1302-3 HGNC:HGNC:35295|Ensembl:ENSG00000221055|miRBase:MI0006364 +100302129 MIR1915 MIM:615202|HGNC:HGNC:35399|Ensembl:ENSG00000222071|miRBase:MI0008336 +100302130 MIR1302-4 HGNC:HGNC:35296|Ensembl:ENSG00000221628|miRBase:MI0006365 +100302131 MIR302F HGNC:HGNC:35349|Ensembl:ENSG00000283218|miRBase:MI0006418 +100302132 MIR1182 HGNC:HGNC:35263|Ensembl:ENSG00000283799|miRBase:MI0006275 +100302133 MIR1287 HGNC:HGNC:35280|Ensembl:ENSG00000284415|miRBase:MI0006349 +100302134 MIR1289-2 HGNC:HGNC:35282|Ensembl:ENSG00000221287|miRBase:MI0006351 +100302135 MIR320C1 HGNC:HGNC:35248|Ensembl:ENSG00000221493|miRBase:MI0003778 +100302136 MIR1252 HGNC:HGNC:35365|Ensembl:ENSG00000221788|miRBase:MI0006434 +100302137 MIR1914 HGNC:HGNC:35398|Ensembl:ENSG00000284433|miRBase:MI0008335 +100302138 MIR1292 MIM:614155|HGNC:HGNC:35364|Ensembl:ENSG00000284481|miRBase:MI0006433 +100302139 MIR1537 HGNC:HGNC:35381|Ensembl:ENSG00000222831|miRBase:MI0007258 +100302140 MIR1302-6 HGNC:HGNC:35298|Ensembl:ENSG00000221393|miRBase:MI0006367 +100302141 MIR1913 HGNC:HGNC:35397|Ensembl:ENSG00000222958|miRBase:MI0008334 +100302142 MIR1246 HGNC:HGNC:35312|Ensembl:ENSG00000283203|miRBase:MI0006381 +100302143 MIR1248 HGNC:HGNC:35314|Ensembl:ENSG00000283958|miRBase:MI0006383 +100302144 MIR1912 HGNC:HGNC:35396|Ensembl:ENSG00000222321|miRBase:MI0008333 +100302145 MIR1247 HGNC:HGNC:35313|Ensembl:ENSG00000283857|miRBase:MI0006382 +100302146 MIR1302-5 HGNC:HGNC:35297|Ensembl:ENSG00000221091|miRBase:MI0006366 +100302147 MIR1302-7 HGNC:HGNC:35299|Ensembl:ENSG00000221768|miRBase:MI0006368 +100302148 MIR1263 HGNC:HGNC:35329|Ensembl:ENSG00000221251|miRBase:MI0006398 +100302149 MIR1249 HGNC:HGNC:35315|Ensembl:ENSG00000221598|miRBase:MI0006384 +100302150 MIR1296 HGNC:HGNC:35249|Ensembl:ENSG00000221063|miRBase:MI0003780 +100302152 MIR548N HGNC:HGNC:35330|Ensembl:ENSG00000221669|miRBase:MI0006399 +100302153 MIR1298 HGNC:HGNC:35258|Ensembl:ENSG00000221710|miRBase:MI0003938 +100302155 MIR1256 HGNC:HGNC:35321|Ensembl:ENSG00000221808|miRBase:MI0006390 +100302156 MIR1229 HGNC:HGNC:33924|Ensembl:ENSG00000221394|miRBase:MI0006319 +100302157 MIR1185-1 HGNC:HGNC:35257|Ensembl:ENSG00000221525|miRBase:MI0003844 +100302158 MIR1231 MIM:617040|HGNC:HGNC:33921|Ensembl:ENSG00000221028|miRBase:MI0006321 +100302159 MIR548F3 HGNC:HGNC:35307|Ensembl:ENSG00000221436|miRBase:MI0006376 +100302160 MIR1233-1 HGNC:HGNC:33929|Ensembl:ENSG00000221649|miRBase:MI0006323 +100302161 MIR1205 HGNC:HGNC:35271|Ensembl:ENSG00000221771|miRBase:MI0006338 +100302163 MIR1278 HGNC:HGNC:35356|Ensembl:ENSG00000221680|miRBase:MI0006425 +100302164 MIR2113 HGNC:HGNC:37058|Ensembl:ENSG00000238367|miRBase:MI0003939 +100302165 MIR1273A HGNC:HGNC:35340|Ensembl:ENSG00000221753|miRBase:MI0006409 +100302166 MIR1322 HGNC:HGNC:35374|Ensembl:ENSG00000283210|miRBase:MI0006653 +100302167 MIR1299 HGNC:HGNC:35290|Ensembl:ENSG00000275377|miRBase:MI0006359 +100302168 MIR1257 HGNC:HGNC:35322|Ensembl:ENSG00000284193|miRBase:MI0006391 +100302169 MIR320D2 HGNC:HGNC:35388|Ensembl:ENSG00000221081|miRBase:MI0008192 +100302170 MIR1206 HGNC:HGNC:35272|Ensembl:ENSG00000283200|miRBase:MI0006339 +100302171 MIR1321 HGNC:HGNC:35373|Ensembl:ENSG00000283435|miRBase:MI0006652 +100302172 MIR1258 MIM:614488|HGNC:HGNC:35323|Ensembl:ENSG00000221240|miRBase:MI0006392 +100302174 MIR1307 HGNC:HGNC:35372|Ensembl:ENSG00000283867|miRBase:MI0006444 +100302175 MIR1207 HGNC:HGNC:35273|Ensembl:ENSG00000221176|miRBase:MI0006340 +100302177 MIR1269A HGNC:HGNC:35337|Ensembl:ENSG00000221563|miRBase:MI0006406 +100302178 MIR1295A HGNC:HGNC:35288|Ensembl:ENSG00000221390|miRBase:MI0006357 +100302179 MIR1270 HGNC:HGNC:35338|Ensembl:ENSG00000238517|miRBase:MI0006407 +100302181 MIR1294 HGNC:HGNC:35287|Ensembl:ENSG00000221430|miRBase:MI0006356 +100302182 MIR1279 HGNC:HGNC:35357|Ensembl:ENSG00000283476|miRBase:MI0006426 +100302183 MIR1825 HGNC:HGNC:35389|Ensembl:ENSG00000284125|miRBase:MI0008193 +100302184 MIR1272 HGNC:HGNC:35339|Ensembl:ENSG00000221033|miRBase:MI0006408 +100302185 MIR1204 HGNC:HGNC:37059|Ensembl:ENSG00000283710|miRBase:MI0006337 +100302186 MIR548I3 HGNC:HGNC:35354|Ensembl:ENSG00000221305|miRBase:MI0006423 +100302187 MIR1297 HGNC:HGNC:35289|Ensembl:ENSG00000283126|miRBase:MI0006358 +100302188 MIR1243 HGNC:HGNC:35304|Ensembl:ENSG00000283193|miRBase:MI0006373 +100302190 MIR1976 HGNC:HGNC:37064|Ensembl:ENSG00000238705|miRBase:MI0009986 +100302191 MIR548I4 HGNC:HGNC:35355|Ensembl:ENSG00000221494|miRBase:MI0006424 +100302192 MIR548F1 HGNC:HGNC:35305|Ensembl:ENSG00000221594|miRBase:MI0006374 +100302193 MIR1255A HGNC:HGNC:35320|Ensembl:ENSG00000221265|miRBase:MI0006389 +100302195 MIR320C2 HGNC:HGNC:35387|Ensembl:ENSG00000212051|miRBase:MI0008191 +100302196 MIR1234 HGNC:HGNC:33926|Ensembl:ENSG00000284139|miRBase:MI0006324 +100302197 MIR1306 HGNC:HGNC:35371|Ensembl:ENSG00000284464|miRBase:MI0006443 +100302201 MIR1228 HGNC:HGNC:33928|Ensembl:ENSG00000221365|miRBase:MI0006318 +100302202 MIR1266 HGNC:HGNC:35334|Ensembl:ENSG00000221052|miRBase:MI0006403 +100302203 MIR1271 HGNC:HGNC:35252|Ensembl:ENSG00000221464|miRBase:MI0003814 +100302204 MIR548I1 HGNC:HGNC:35352|Ensembl:ENSG00000221737|miRBase:MI0006421 +100302205 MIR1283-2 HGNC:HGNC:35361|Ensembl:ENSG00000221548|miRBase:MI0006430 +100302208 MIR1253 HGNC:HGNC:35318|Ensembl:ENSG00000221200|miRBase:MI0006387 +100302209 MIR1185-2 HGNC:HGNC:35254|Ensembl:ENSG00000221614|miRBase:MI0003821 +100302210 MIR1909 MIM:615201|HGNC:HGNC:35393|Ensembl:ENSG00000284216|miRBase:MI0008330 +100302211 MIR1203 HGNC:HGNC:35269|Ensembl:ENSG00000221739|miRBase:MI0006335 +100302212 MIR1324 HGNC:HGNC:35377|Ensembl:ENSG00000283894|miRBase:MI0006657 +100302213 MIR1181 HGNC:HGNC:35262|Ensembl:ENSG00000284268|miRBase:MI0006274 +100302214 MIR1277 HGNC:HGNC:35350|Ensembl:ENSG00000221463|miRBase:MI0006419 +100302217 MIR1827 HGNC:HGNC:35391|Ensembl:ENSG00000221476|miRBase:MI0008195 +100302218 MIR1285-1 HGNC:HGNC:35277|Ensembl:ENSG00000221520|miRBase:MI0006346 +100302219 MIR1245A HGNC:HGNC:35311|Ensembl:ENSG00000221502|miRBase:MI0006380 +100302220 MIR1293 HGNC:HGNC:35286|Ensembl:ENSG00000221604|miRBase:MI0006355 +100302221 MIR1291 HGNC:HGNC:35284|Ensembl:ENSG00000281842|miRBase:MI0006353 +100302222 MIR1911 HGNC:HGNC:35395|Ensembl:ENSG00000222715|miRBase:MI0008332 +100302223 MIR1302-8 HGNC:HGNC:35300|Ensembl:ENSG00000221269|miRBase:MI0006369 +100302224 MIR2110 HGNC:HGNC:37071|Ensembl:ENSG00000284442|miRBase:MI0010629 +100302225 MIR2053 HGNC:HGNC:37069|Ensembl:ENSG00000238399|miRBase:MI0010487 +100302226 MIR1238 HGNC:HGNC:33933|Ensembl:ENSG00000221410|miRBase:MI0006328 +100302227 MIR1302-1 HGNC:HGNC:35293|Ensembl:ENSG00000283507|miRBase:MI0006362 +100302228 MIR1261 HGNC:HGNC:35327|Ensembl:ENSG00000221586|miRBase:MI0006396 +100302229 MIR1250 HGNC:HGNC:35316|Ensembl:ENSG00000221025|miRBase:MI0006385 +100302232 MIR1226 HGNC:HGNC:33922|Ensembl:ENSG00000221585|miRBase:MI0006313 +100302233 MIR1268A HGNC:HGNC:35336|Ensembl:ENSG00000221641|miRBase:MI0006405 +100302234 MIR664A HGNC:HGNC:35370|Ensembl:ENSG00000281696|miRBase:MI0006442 +100302235 MIR1179 HGNC:HGNC:35260|Ensembl:ENSG00000221630|miRBase:MI0006272 +100302236 MIR1260A HGNC:HGNC:35325|Ensembl:ENSG00000221754|miRBase:MI0006394 +100302237 MIR1281 HGNC:HGNC:35359|Ensembl:ENSG00000284015|miRBase:MI0006428 +100302238 MIR103B1 HGNC:HGNC:35384|Ensembl:ENSG00000283612|miRBase:MI0007261 +100302239 MIR548F5 HGNC:HGNC:35309|Ensembl:ENSG00000221348|miRBase:MI0006378 +100302240 MIR1304 HGNC:HGNC:35302|Ensembl:ENSG00000284458|miRBase:MI0006371 +100302242 MIR1236 HGNC:HGNC:33925|Ensembl:ENSG00000284446|miRBase:MI0006326 +100302243 MIR1972-1 HGNC:HGNC:37060|Ensembl:ENSG00000238728|miRBase:MI0009982 +100302246 MIR1301 HGNC:HGNC:35253|Ensembl:ENSG00000221445|miRBase:MI0003815 +100302250 MIR1197 HGNC:HGNC:35376|Ensembl:ENSG00000221745|miRBase:MI0006656 +100302251 MIR1264 HGNC:HGNC:35246|Ensembl:ENSG00000276158|miRBase:MI0003758 +100302254 MIR1282 HGNC:HGNC:35360|Ensembl:ENSG00000221792|miRBase:MI0006429 +100302255 MIR1323 HGNC:HGNC:35251|Ensembl:ENSG00000221017|miRBase:MI0003786 +100302256 MIR1180 HGNC:HGNC:35261|Ensembl:ENSG00000221540|miRBase:MI0006273 +100302257 MIR1539 HGNC:HGNC:35383|Ensembl:ENSG00000284239|miRBase:MI0007260 +100302258 MIR1469 HGNC:HGNC:35378|Ensembl:ENSG00000283888|miRBase:MI0007074 +100302259 MIR1202 HGNC:HGNC:35268|Ensembl:ENSG00000221456|miRBase:MI0006334 +100302260 MIR2052 HGNC:HGNC:37068|Ensembl:ENSG00000283188|miRBase:MI0010486 +100302261 MIR1910 HGNC:HGNC:35394|Ensembl:ENSG00000283416|miRBase:MI0008331 +100302263 MIR1908 HGNC:HGNC:35392|Ensembl:ENSG00000284416|miRBase:MI0008329 +100302265 MIR1283-1 HGNC:HGNC:35255|Ensembl:ENSG00000221421|miRBase:MI0003832 +100302267 MIR2054 HGNC:HGNC:37070|Ensembl:ENSG00000283550|miRBase:MI0010488 +100302268 MIR1285-2 HGNC:HGNC:35278|Ensembl:ENSG00000221238|miRBase:MI0006347 +100302270 MIR1305 HGNC:HGNC:35303|Ensembl:ENSG00000221227|miRBase:MI0006372 +100302273 MIR1254-1 HGNC:HGNC:35319|Ensembl:ENSG00000221184|miRBase:MI0006388 +100302274 MIR1178 HGNC:HGNC:35259|Ensembl:ENSG00000283768|miRBase:MI0006271 +100302275 MIR548L HGNC:HGNC:35292|Ensembl:ENSG00000221230|miRBase:MI0006361 +100302276 MIR1290 HGNC:HGNC:35283|Ensembl:ENSG00000221662|miRBase:MI0006352 +100302277 MIR548I2 HGNC:HGNC:35353|Ensembl:ENSG00000221275|miRBase:MI0006422 +100302278 MIR1302-2 HGNC:HGNC:35294|Ensembl:ENSG00000284332|miRBase:MI0006363 +100302279 MIR1262 HGNC:HGNC:35328|Ensembl:ENSG00000221203|miRBase:MI0006397 +100302280 MIR1237 HGNC:HGNC:33927|Ensembl:ENSG00000221273|miRBase:MI0006327 +100302281 MIR1208 HGNC:HGNC:35274|Ensembl:ENSG00000221261|miRBase:MI0006341 +100302282 MIR103B2 HGNC:HGNC:35385|Ensembl:ENSG00000283320|miRBase:MI0007262 +100302283 MIR1227 HGNC:HGNC:33932|Ensembl:ENSG00000221411|miRBase:MI0006316 +100302284 MIR1303 HGNC:HGNC:35301|Ensembl:ENSG00000221552|miRBase:MI0006370 +100302285 MIR1244-1 HGNC:HGNC:35310|Ensembl:ENSG00000284378|miRBase:MI0006379 +100302286 MIR1267 HGNC:HGNC:35335|Ensembl:ENSG00000221650|miRBase:MI0006404 +100302287 MIR548H3 HGNC:HGNC:35344|Ensembl:ENSG00000221698|miRBase:MI0006413 +100302288 MIR548P HGNC:HGNC:35351|Ensembl:ENSG00000221263|miRBase:MI0006420 +100302289 MIR1251 HGNC:HGNC:35317|Ensembl:ENSG00000221479|miRBase:MI0006386 +100302290 MIR1973 HGNC:HGNC:37061|Ensembl:ENSG00000284253|miRBase:MI0009983 +100302291 LOC100302291 - +100302401 RASAL2-AS1 HGNC:HGNC:44170|Ensembl:ENSG00000224687 +100302509 LECD MIM:300778 +100302510 XECD MIM:300779 +100302511 EOE1 MIM:610247 +100302512 RLS6 MIM:611185 +100302513 DFNB71 MIM:612789|HGNC:HGNC:33172 +100302514 NRCLP5 MIM:612851 +100302515 OFC12 MIM:612858 +100302516 CTEPH1 MIM:612862 +100302517 MENOQ2 MIM:612884 +100302518 MENOQ3 MIM:612885 +100302519 MENOQ4 MIM:612886 +100302522 PTCSC1 MIM:617440|HGNC:HGNC:37127 +100302526 FAM41AY2 HGNC:HGNC:37135 +100302559 PURAQTL1 MIM:612795 +100302560 MUHH2 MIM:612841 +100302561 RLS7 MIM:612853 +100302562 MENAQ2 MIM:612882 +100302563 MENAQ3 MIM:612883 +100302591 LOC100302591 - +100302640 LINC00882 HGNC:HGNC:48568|Ensembl:ENSG00000242759 +100302650 BRE-AS1 HGNC:HGNC:44171 +100302652 GPR75-ASB3 HGNC:HGNC:40043|Ensembl:ENSG00000270898|Vega:OTTHUMG00000129279 +100302657 DDX11L3 HGNC:HGNC:37104 +100302666 CSPG4P13 HGNC:HGNC:49195 +100302680 DELXQ28 MIM:300475 +100302681 PVNH3 MIM:608098 +100302682 PVNH5 MIM:612881 +100302683 STQTL18 MIM:612892 +100302684 STQTL19 MIM:612893 +100302685 STQTL20 MIM:612894 +100302686 MTBS3 MIM:612929 +100302689 GPN3P1 HGNC:HGNC:44914 +100302690 DLG2-AS1 HGNC:HGNC:37132 +100302691 LINC00184 HGNC:HGNC:37192|Ensembl:ENSG00000224939 +100302692 FTX MIM:300936|HGNC:HGNC:37190|Ensembl:ENSG00000230590 +100302716 HTGH MIM:135400 +100302718 B6QTL1 MIM:612957 +100302719 BMIQ15 MIM:612967 +100302720 CTRCT34 MIM:612968 +100302721 ARHI2 MIM:612976 +100302736 TMED7-TICAM2 HGNC:HGNC:33945|Ensembl:ENSG00000251201|Vega:OTTHUMG00000162911 +100302737 ZNF861P HGNC:HGNC:34514 +100302738 RNU6-21P HGNC:HGNC:34265 +100302739 PCNA-AS1 HGNC:HGNC:37184 +100302740 FAS-AS1 HGNC:HGNC:37128 +100302741 RNU6-15P HGNC:HGNC:34259 +100302742 RNU6-42P HGNC:HGNC:34286 +100302743 SNORA80B HGNC:HGNC:34355|Ensembl:ENSG00000206633 +100302746 NCRUPAR HGNC:HGNC:37153 +100302751 NCLP1 HGNC:HGNC:35472 +100303453 TSNAX-DISC1 HGNC:HGNC:49177|Ensembl:ENSG00000270106|Vega:OTTHUMG00000183905 +100303491 ZEB2-AS1 HGNC:HGNC:37149|Ensembl:ENSG00000238057 +100303715 IDDM24 MIM:613006 +100303716 PBC2 MIM:613007 +100303717 PBC3 MIM:613008 +100303728 SLC25A5-AS1 HGNC:HGNC:43438|Ensembl:ENSG00000224281 +100303743 LSM3P5 HGNC:HGNC:44350 +100303745 LSM3P2 HGNC:HGNC:44347 +100303748 LSM3P1 HGNC:HGNC:44346 +100303749 LOC100303749 - +100303755 PET117 MIM:614771|HGNC:HGNC:40045|Ensembl:ENSG00000232838|Vega:OTTHUMG00000186019 +100306937 NBLST4 MIM:613015 +100306938 NBLST5 MIM:613016 +100306939 NBLST6 MIM:613017 +100306940 FL1 MIM:613024 +100306951 PITPNA-AS1 HGNC:HGNC:44116|Ensembl:ENSG00000236618 +100306975 NDUFAF4P1 HGNC:HGNC:44194 +100306978 DEL19Q13.11 MIM:613026 +100306979 ATFB8 MIM:613055 +100307118 BCC1 MIM:605462 +100307119 BCC2 MIM:613058 +100307120 BCC3 MIM:613059 +100307121 BCC4 MIM:613061 +100307122 BCC5 MIM:613062 +100307123 BCC6 MIM:613063 +100307126 CHMP4BP1 HGNC:HGNC:43616 +100309464 OTX2-AS1 HGNC:HGNC:43906|Ensembl:ENSG00000248550 +100310754 DUPXP11.23P11.22 MIM:300801 +100310755 ATOD7 MIM:613064 +100310756 LOC100310756 - +100310782 LOC100310782 - +100310785 ALL1 MIM:613065 +100310786 ALL2 MIM:613067 +100310812 SPDYE2B HGNC:HGNC:48334|Ensembl:ENSG00000173678|Vega:OTTHUMG00000158393 +100310835 LOC100310835 - +100310838 VDAC1P3 HGNC:HGNC:37478 +100310839 VDAC1P7 HGNC:HGNC:37482 +100310840 VDAC1P8 HGNC:HGNC:37483 +100310841 VDAC1P11 HGNC:HGNC:37480 +100310842 RBPJP1 HGNC:HGNC:5725 +100310846 ANKRD61 HGNC:HGNC:22467|Ensembl:ENSG00000157999|Vega:OTTHUMG00000154561 +100310848 SNRPCP4 HGNC:HGNC:49819 +100310849 SNRPCP19 HGNC:HGNC:49834 +100310850 SNRPCP11 HGNC:HGNC:49826 +100310851 SNRPCP8 HGNC:HGNC:49823 +100310852 SNRPCP7 HGNC:HGNC:49822 +100310853 SNRPCP9 HGNC:HGNC:49824 +100310854 SNRPCP12 HGNC:HGNC:49827 +100310855 SNRPCP14 HGNC:HGNC:49829 +100310856 SNRPCP6 HGNC:HGNC:49821 +100310857 SNRPCP15 HGNC:HGNC:49830 +100310869 IGKV2OR2-7D HGNC:HGNC:37489|IMGT/GENE-DB:IGKV2/OR2-7D +100312774 VN1R56P HGNC:HGNC:37376 +100312775 VN1R20P HGNC:HGNC:37335 +100312781 VN1R24P HGNC:HGNC:37344 +100312782 VN1R25P HGNC:HGNC:37345 +100312783 VN1R26P HGNC:HGNC:37346 +100312784 VN1R27P HGNC:HGNC:37347 +100312785 VN1R28P HGNC:HGNC:37348 +100312786 VN1R29P HGNC:HGNC:37349 +100312787 VN1R31P HGNC:HGNC:37351 +100312788 VN1R32P HGNC:HGNC:37352 +100312789 VN1R35P HGNC:HGNC:37355 +100312790 VN1R36P HGNC:HGNC:37356 +100312791 VN1R39P HGNC:HGNC:37359 +100312792 VN1R40P HGNC:HGNC:37360 +100312793 VN1R41P HGNC:HGNC:37361 +100312794 VN1R42P HGNC:HGNC:37362 +100312795 VN1R43P HGNC:HGNC:37363 +100312796 VN1R45P HGNC:HGNC:37365 +100312797 VN1R47P HGNC:HGNC:37367 +100312798 VN1R48P HGNC:HGNC:37368 +100312799 VN1R49P HGNC:HGNC:37369 +100312801 VN1R51P HGNC:HGNC:37371 +100312802 VN1R52P HGNC:HGNC:37372 +100312803 VN1R110P HGNC:HGNC:37438 +100312804 VN1R15P HGNC:HGNC:37327 +100312805 VN1R16P HGNC:HGNC:37330 +100312806 VN1R53P HGNC:HGNC:37373 +100312807 VN1R54P HGNC:HGNC:37374 +100312808 VN1R55P HGNC:HGNC:37375 +100312809 VN1R57P HGNC:HGNC:37377 +100312810 VN1R58P HGNC:HGNC:37378 +100312811 VN1R59P HGNC:HGNC:37379 +100312812 VN1R60P HGNC:HGNC:37380 +100312813 VN1R61P HGNC:HGNC:37381 +100312814 VN1R62P HGNC:HGNC:37382 +100312815 VN1R63P HGNC:HGNC:37383 +100312816 VN1R69P HGNC:HGNC:37390 +100312817 VN1R71P HGNC:HGNC:37392 +100312818 VN1R73P HGNC:HGNC:37394 +100312819 VN1R74P HGNC:HGNC:37395 +100312820 VN1R75P HGNC:HGNC:37396 +100312821 VN1R76P HGNC:HGNC:37397 +100312822 VN1R77P HGNC:HGNC:37398 +100312823 VN1R78P HGNC:HGNC:37399 +100312824 VN1R79P HGNC:HGNC:37400 +100312825 VN1R80P HGNC:HGNC:37329 +100312826 VN1R81P HGNC:HGNC:37401 +100312827 VN1R82P HGNC:HGNC:37402 +100312828 VN1R83P HGNC:HGNC:37403 +100312829 VN1R84P HGNC:HGNC:37404 +100312830 VN1R85P HGNC:HGNC:37405 +100312831 VN1R86P HGNC:HGNC:37406 +100312832 VN1R87P HGNC:HGNC:37407 +100312833 VN1R88P HGNC:HGNC:37408 +100312834 VN1R89P HGNC:HGNC:37409 +100312835 VN1R90P HGNC:HGNC:37410 +100312836 VN1R91P HGNC:HGNC:37411 +100312837 VN1R92P HGNC:HGNC:37412 +100312838 VN1R93P HGNC:HGNC:37413 +100312839 VN1R94P HGNC:HGNC:37414 +100312840 VN1R97P HGNC:HGNC:37417 +100312841 VN1R98P HGNC:HGNC:37418 +100312842 VN1R99P HGNC:HGNC:37419 +100312843 VN1R19P HGNC:HGNC:37328 +100312844 VN1R22P HGNC:HGNC:37337 +100312845 VN1R23P HGNC:HGNC:37338 +100312846 VN1R100P HGNC:HGNC:37420 +100312847 VN1R102P HGNC:HGNC:37425 +100312848 VN1R106P HGNC:HGNC:37429 +100312849 VN1R107P HGNC:HGNC:37431 +100312850 VN1R108P HGNC:HGNC:37432 +100312851 VN1R109P HGNC:HGNC:37434 +100312852 VN1R111P HGNC:HGNC:37332 +100312853 VN1R72P HGNC:HGNC:37393 +100312854 VN1R112P HGNC:HGNC:37437 +100312855 VN1R44P HGNC:HGNC:37364 +100312951 NPCA2 MIM:161550 +100312952 PVOP1 MIM:176780 +100312954 GRD1 MIM:275000 +100312955 PVOP2 MIM:613088 +100312985 IGKV1OR15-118 HGNC:HGNC:5765|IMGT/GENE-DB:IGKV1/OR15-118 +100313532 MFSD1P1 HGNC:HGNC:50625 +100313769 MIR320B2 HGNC:HGNC:35256|Ensembl:ENSG00000221406|miRBase:MI0003839 +100313770 MIR548K HGNC:HGNC:35285|Ensembl:ENSG00000221333|miRBase:MI0006354 +100313771 MIR548F2 HGNC:HGNC:35306|Ensembl:ENSG00000221782|miRBase:MI0006375 +100313772 MIR548M HGNC:HGNC:35331|Ensembl:ENSG00000221187|miRBase:MI0006400 +100313773 MIR548H2 HGNC:HGNC:35343|Ensembl:ENSG00000221801|miRBase:MI0006412 +100313774 MIR302E HGNC:HGNC:35348|Ensembl:ENSG00000221703|miRBase:MI0006417 +100313777 MIR670 HGNC:HGNC:37304|Ensembl:ENSG00000211568|miRBase:MI0003933 +100313778 MIR759 HGNC:HGNC:37307|Ensembl:ENSG00000211579|miRBase:MI0004065 +100313779 MIR2117 HGNC:HGNC:37311|Ensembl:ENSG00000284344|miRBase:MI0010636 +100313780 MIR2278 HGNC:HGNC:37315|Ensembl:ENSG00000252153|miRBase:MI0011285 +100313781 MIR718 MIM:300929|HGNC:HGNC:37317|Ensembl:ENSG00000284286|miRBase:MI0012489 +100313782 PIRC7 HGNC:HGNC:37511 +100313783 PIRC10 HGNC:HGNC:37514 +100313784 PIRC14 HGNC:HGNC:37518 +100313785 PIRC20 HGNC:HGNC:37524 +100313786 PIRC23 HGNC:HGNC:37527 +100313787 PIRC31 HGNC:HGNC:37535 +100313788 PIRC38 HGNC:HGNC:37542 +100313789 PIRC42 HGNC:HGNC:37546 +100313790 PIRC48 HGNC:HGNC:37552 +100313791 PIRC52 HGNC:HGNC:37556 +100313792 PIRC55 HGNC:HGNC:37559 +100313793 PIRC63 HGNC:HGNC:37567 +100313794 PIRC65 HGNC:HGNC:37569 +100313795 PIRC73 HGNC:HGNC:37577 +100313796 PIRC76 HGNC:HGNC:37580 +100313797 PIRC79 HGNC:HGNC:37583 +100313798 PIRC90 HGNC:HGNC:37594 +100313799 PIRC94 HGNC:HGNC:37598 +100313800 PIRC96 HGNC:HGNC:37600 +100313801 PIRC104 HGNC:HGNC:37608 +100313802 PIRC107 HGNC:HGNC:37611 +100313803 PIRC112 HGNC:HGNC:37616 +100313806 MIR1255B1 HGNC:HGNC:35366|Ensembl:ENSG00000283207|miRBase:MI0006435 +100313807 PIRC4 HGNC:HGNC:37508 +100313808 PIRC12 HGNC:HGNC:37516 +100313809 PIRC17 HGNC:HGNC:37521 +100313810 PIRC24 HGNC:HGNC:37528 +100313811 PIRC32 HGNC:HGNC:37536 +100313812 PIRC37 HGNC:HGNC:37541 +100313813 PIRC45 HGNC:HGNC:37549 +100313814 PIRC50 HGNC:HGNC:37554 +100313815 PIRC54 HGNC:HGNC:37558 +100313816 PIRC62 HGNC:HGNC:37566 +100313817 PIRC67 HGNC:HGNC:37571 +100313818 PIRC71 HGNC:HGNC:37575 +100313819 PIRC80 HGNC:HGNC:37584 +100313820 PIRC84 HGNC:HGNC:37588 +100313821 PIRC97 HGNC:HGNC:37601 +100313822 MIR513B HGNC:HGNC:33935|Ensembl:ENSG00000207871|miRBase:MI0006648 +100313824 MIR663B HGNC:HGNC:35270|Ensembl:ENSG00000221288|miRBase:MI0006336 +100313829 MIR548O HGNC:HGNC:35333|Ensembl:ENSG00000221510|miRBase:MI0006402 +100313830 MIR548H1 HGNC:HGNC:35342|Ensembl:ENSG00000221537|miRBase:MI0006411 +100313835 MIR1255B2 HGNC:HGNC:35367|Ensembl:ENSG00000221545|miRBase:MI0006436 +100313837 MIR762 HGNC:HGNC:37303|Ensembl:ENSG00000211591|miRBase:MI0003892 +100313838 MIR764 HGNC:HGNC:37306|Ensembl:ENSG00000212100|miRBase:MI0003944 +100313839 MIR2114 HGNC:HGNC:37308|Ensembl:ENSG00000252454|miRBase:MI0010633 +100313840 MIR2115 HGNC:HGNC:37309|Ensembl:ENSG00000252466|miRBase:MI0010634 +100313841 MIR548Q HGNC:HGNC:37312|Ensembl:ENSG00000221331|miRBase:MI0010637 +100313842 MIR2276 HGNC:HGNC:37313|Ensembl:ENSG00000252695|miRBase:MI0011282 +100313843 MIR711 HGNC:HGNC:37316|Ensembl:ENSG00000284251|miRBase:MI0012488 +100313844 PIRC1 HGNC:HGNC:37505 +100313845 PIRC5 HGNC:HGNC:37509 +100313846 PIRC6 HGNC:HGNC:37510 +100313847 PIRC9 HGNC:HGNC:37513 +100313848 PIRC15 HGNC:HGNC:37519 +100313849 PIRC16 HGNC:HGNC:37520 +100313850 PIRC22 HGNC:HGNC:37526 +100313851 PIRC25 HGNC:HGNC:37529 +100313852 PIRC26 HGNC:HGNC:37530 +100313853 PIRC30 HGNC:HGNC:37534 +100313854 PIRC33 HGNC:HGNC:37537 +100313855 PIRC35 HGNC:HGNC:37539 +100313856 PIRC39 HGNC:HGNC:37543 +100313857 PIRC43 HGNC:HGNC:37547 +100313858 PIRC46 HGNC:HGNC:37550 +100313859 PIRC47 HGNC:HGNC:37551 +100313860 PIRC51 HGNC:HGNC:37555 +100313861 PIRC53 HGNC:HGNC:37557 +100313862 PIRC56 HGNC:HGNC:37560 +100313863 PIRC60 HGNC:HGNC:37564 +100313864 PIRC64 HGNC:HGNC:37568 +100313865 PIRC66 HGNC:HGNC:37570 +100313866 PIRC70 HGNC:HGNC:37574 +100313867 PIRC72 HGNC:HGNC:37576 +100313868 PIRC77 HGNC:HGNC:37581 +100313869 PIRC78 HGNC:HGNC:37582 +100313870 PIRC81 HGNC:HGNC:37585 +100313871 PIRC85 HGNC:HGNC:37589 +100313872 PIRC87 HGNC:HGNC:37591 +100313873 PIRC89 HGNC:HGNC:37593 +100313874 PIRC98 HGNC:HGNC:37602 +100313875 PIRC99 HGNC:HGNC:37603 +100313876 PIRC102 HGNC:HGNC:37606 +100313877 PIRC106 HGNC:HGNC:37610 +100313878 PIRC108 HGNC:HGNC:37612 +100313879 PIRC110 HGNC:HGNC:37614 +100313880 PIRC113 HGNC:HGNC:37617 +100313881 PIRC114 HGNC:HGNC:37618 +100313884 MIR548H4 HGNC:HGNC:35345|Ensembl:ENSG00000221616|miRBase:MI0006414 +100313886 MIR2116 HGNC:HGNC:37310|Ensembl:ENSG00000253030|miRBase:MI0010635 +100313887 MIR2277 HGNC:HGNC:37314|Ensembl:ENSG00000284336|miRBase:MI0011284 +100313888 PIRC101 HGNC:HGNC:37605 +100313890 PIRC34 HGNC:HGNC:37538 +100313891 PIRC83 HGNC:HGNC:37587 +100313892 MIR761 HGNC:HGNC:37305|Ensembl:ENSG00000283899|miRBase:MI0003941 +100313893 PIRC28 HGNC:HGNC:37532 +100313894 PIRC88 HGNC:HGNC:37592 +100313895 MIR548F4 HGNC:HGNC:35308|Ensembl:ENSG00000221442|miRBase:MI0006377 +100313896 MIR320D1 HGNC:HGNC:35386|Ensembl:ENSG00000211491|miRBase:MI0008190 +100313897 PIRC11 HGNC:HGNC:37515 +100313898 PIRC40 HGNC:HGNC:37544 +100313899 PIRC61 HGNC:HGNC:37565 +100313900 PIRC91 HGNC:HGNC:37595 +100313901 PIRC103 HGNC:HGNC:37607 +100313905 PIRC3 HGNC:HGNC:37507 +100313906 PIRC18 HGNC:HGNC:37522 +100313907 PIRC27 HGNC:HGNC:37531 +100313908 PIRC44 HGNC:HGNC:37548 +100313909 PIRC59 HGNC:HGNC:37563 +100313910 PIRC69 HGNC:HGNC:37573 +100313911 PIRC86 HGNC:HGNC:37590 +100313912 PIRC100 HGNC:HGNC:37604 +100313913 PIRC109 HGNC:HGNC:37613 +100313914 MIR548J HGNC:HGNC:35276|Ensembl:ENSG00000221760|miRBase:MI0006345 +100313915 PIRC8 HGNC:HGNC:37512 +100313916 PIRC21 HGNC:HGNC:37525 +100313917 PIRC41 HGNC:HGNC:37545 +100313918 PIRC58 HGNC:HGNC:37562 +100313919 PIRC75 HGNC:HGNC:37579 +100313920 PIRC92 HGNC:HGNC:37596 +100313921 MIR548E HGNC:HGNC:35275|Ensembl:ENSG00000221214|miRBase:MI0006344 +100313923 MIR449C HGNC:HGNC:37302|Ensembl:ENSG00000251856|miRBase:MI0003823 +100313924 PIRC2 HGNC:HGNC:37506 +100313925 PIRC13 HGNC:HGNC:37517 +100313926 PIRC19 HGNC:HGNC:37523 +100313927 PIRC29 HGNC:HGNC:37533 +100313928 PIRC36 HGNC:HGNC:37540 +100313929 PIRC49 HGNC:HGNC:37553 +100313930 PIRC57 HGNC:HGNC:37561 +100313931 PIRC68 HGNC:HGNC:37572 +100313932 PIRC74 HGNC:HGNC:37578 +100313933 PIRC82 HGNC:HGNC:37586 +100313934 PIRC93 HGNC:HGNC:37597 +100313935 PIRC95 HGNC:HGNC:37599 +100313936 PIRC105 HGNC:HGNC:37609 +100313937 PIRC111 HGNC:HGNC:37615 +100313938 MIR548G HGNC:HGNC:35326|Ensembl:ENSG00000221369|miRBase:MI0006395 +100313942 LOC100313942 - +100313948 BRV2 MIM:613106 +100313962 RFKP1 HGNC:HGNC:39181 +100313968 LOC100313968 - +100316847 GLM8 MIM:613033 +100316867 ARF4P5 HGNC:HGNC:37629 +100316868 HOTTIP MIM:614060|HGNC:HGNC:37461 +100316904 SAP25 HGNC:HGNC:41908|Ensembl:ENSG00000205307|Vega:OTTHUMG00000187472 +100322878 SLEB14 MIM:613145 +100322879 SPG45 MIM:613162|HGNC:HGNC:35431 +100327036 PPP2R2DP1 HGNC:HGNC:44544 +100328982 LOC100328982 - +100329108 GCSHP5 HGNC:HGNC:44195 +100329109 GCSHP3 HGNC:HGNC:43929 +100329129 LOC100329129 - +100329135 TRPC5OS HGNC:HGNC:40593|Ensembl:ENSG00000204025|Vega:OTTHUMG00000022211 +100329167 AAA1 MIM:100070 +100329168 LGV2 MIM:606460 +100329169 CRCS9 MIM:612590 +100329170 SCZD13 MIM:613025 +100335030 LOC100335030 - +100337589 FMO7P HGNC:HGNC:32208 +100337590 FMO11P HGNC:HGNC:32212 +100337591 SNORA70F HGNC:HGNC:34358|Ensembl:ENSG00000206869 +100337616 CSN1S2BP HGNC:HGNC:20227 +100337622 DDX11L4 HGNC:HGNC:37105 +100337646 CT45B1P HGNC:HGNC:33580 +100359393 SCA30 MIM:613371|HGNC:HGNC:33445 +100359394 LINC00102 HGNC:HGNC:30470|Ensembl:ENSG00000230542 +100359395 DFNA58 MIM:615654|HGNC:HGNC:34029 +100359396 HSPD1P11 HGNC:HGNC:35142 +100359397 HSPD1P18 HGNC:HGNC:35136 +100359399 DFNB85 MIM:613392|HGNC:HGNC:37053 +100359400 DFNB83 MIM:613685|HGNC:HGNC:37051 +100359401 MYP17 MIM:608367|HGNC:HGNC:37047 +100359402 SPG41 MIM:613364|HGNC:HGNC:34382 +100359403 PARK16 MIM:613164|HGNC:HGNC:37450 +100359406 MYP18 MIM:255500|HGNC:HGNC:37048 +100359407 MYP14 MIM:610320|HGNC:HGNC:35439 +100379132 SNORA70G HGNC:HGNC:34359|Ensembl:ENSG00000206650 +100379141 SNORA70D HGNC:HGNC:34356|Ensembl:ENSG00000263666 +100379142 NCLP2 HGNC:HGNC:35473 +100379174 MACROD2-AS1 HGNC:HGNC:37193|Ensembl:ENSG00000235914 +100379198 ECT MIM:117100 +100379199 HRM2 MIM:139450 +100379200 SLEB15 MIM:300809 +100379201 SPAX3 MIM:611390 +100379202 DUP5P13 MIM:613174 +100379203 DUP17P13.3 MIM:613215 +100379215 QTV MIM:610141 +100379216 FGQTL2 MIM:613219 +100379217 FGQTL3 MIM:613233 +100379218 SPDA3 MIM:613238 +100379220 TMED11P HGNC:HGNC:35401|Ensembl:ENSG00000215367 +100379224 LOC100379224 Ensembl:ENSG00000186019 +100379236 LOC100379236 - +100379249 BOK-AS1 HGNC:HGNC:35125 +100379250 SNORA70E HGNC:HGNC:34357|Ensembl:ENSG00000207221 +100379251 NPPA-AS1 HGNC:HGNC:37635 +100379287 RNY4P6 HGNC:HGNC:34055 +100379288 RNY4P11 HGNC:HGNC:34061 +100379290 LOC100379290 - +100379291 RNY4P15 HGNC:HGNC:34065 +100379295 RNY4P8 HGNC:HGNC:34057 +100379296 RNY4P13 HGNC:HGNC:34063 +100379297 RNY4P4 HGNC:HGNC:34050 +100379298 RNY4P18 HGNC:HGNC:34068 +100379299 RNY4P5 HGNC:HGNC:34052 +100379300 RNY4P9 HGNC:HGNC:34058 +100379323 ERVW-2 HGNC:HGNC:37653 +100379345 MIR181A2HG HGNC:HGNC:37188|Ensembl:ENSG00000224020 +100379378 RNY4P20 HGNC:HGNC:34070 +100379564 RNY4P17 HGNC:HGNC:34067 +100379571 BACE1-AS MIM:614263|HGNC:HGNC:37125 +100379584 RNY4P14 HGNC:HGNC:34064 +100379592 RNY4P10 HGNC:HGNC:34060 +100379623 LARP1P1 HGNC:HGNC:23183 +100379658 RNY5P5 HGNC:HGNC:34086 +100379661 GRIK1-AS2 HGNC:HGNC:1282|Ensembl:ENSG00000156273 +100379663 RNY5P6 HGNC:HGNC:34087 +100379664 RNY5P3 HGNC:HGNC:34084 +100379666 RNY5P1 HGNC:HGNC:34082 +100379667 NEK2P2 HGNC:HGNC:37816 +100380271 RNY5P4 HGNC:HGNC:34085 +100380272 NDUFB1P2 HGNC:HGNC:37815 +100380873 FECD3 MIM:613267 +100380874 FECD5 MIM:613269 +100380875 FECD7 MIM:613271 +100380876 NAFLD1 MIM:613282 +100380878 RNY5P8 HGNC:HGNC:34089 +100380945 ZNF848P HGNC:HGNC:34387 +100381178 TMPRSS11CP HGNC:HGNC:31934 +100381202 NEK2P4 HGNC:HGNC:37818 +100381204 HCHGQ1 MIM:609319 +100381205 HCHGQ2 MIM:609320 +100381206 HCHGQ3 MIM:613284 +100381207 CIHL MIM:613290 +100381208 RNY5P2 HGNC:HGNC:34083 +100381210 CAMPD1 MIM:114200 +100381211 ARCODS MIM:602483 +100381215 DYNLT3P2 HGNC:HGNC:37081 +100381270 ZBED6 MIM:613512|HGNC:HGNC:33273|Ensembl:ENSG00000257315|Vega:OTTHUMG00000170422 +100384884 IGHV1OR15-5 HGNC:HGNC:5567|IMGT/GENE-DB:IGHV1/OR15-5 +100384885 LOC100384885 - +100415893 DUPXQ28 MIM:300815 +100415894 GLM5 MIM:613030 +100415895 GLM6 MIM:613031 +100415896 ASRT8 MIM:613207 +100415903 HWE1 MIM:613339 +100415904 HWE2 MIM:613340 +100415941 DEL17Q23.1Q23.2 MIM:613355 +100415942 DEL2P21 MIM:606407 +100415943 MGR9 MIM:609670 +100418696 LOC100418696 - +100418700 LOC100418700 - +100418701 LOC100418701 - +100418703 LOC100418703 - +100418705 LOC100418705 - +100418706 FXNP2 HGNC:HGNC:51607 +100418707 LOC100418707 - +100418708 CLUHP1 HGNC:HGNC:38416 +100418709 CLUHP2 HGNC:HGNC:38453 +100418710 LOC100418710 - +100418711 CLUHP4 HGNC:HGNC:38470 +100418712 LOC100418712 - +100418713 LOC100418713 - +100418714 LOC100418714 - +100418715 SEPT7P4 HGNC:HGNC:38039 +100418716 LOC100418716 - +100418718 SEPT7P5 HGNC:HGNC:38041 +100418719 CLUHP7 HGNC:HGNC:51570 +100418720 SEPT7P6 HGNC:HGNC:38042 +100418721 LOC100418721 - +100418723 LOC100418723 - +100418724 CCNJP2 HGNC:HGNC:37997 +100418728 KRT8P40 HGNC:HGNC:39874 +100418730 LOC100418730 - +100418731 AKIRIN1P1 HGNC:HGNC:50794 +100418732 LOC100418732 - +100418733 CLUHP8 HGNC:HGNC:51573 +100418734 LOC100418734 - +100418735 SEPT7P8 HGNC:HGNC:38044 +100418736 GOLGA5P1 HGNC:HGNC:43925 +100418737 KRT8P33 HGNC:HGNC:39867 +100418739 DNM1P48 HGNC:HGNC:38801 +100418740 PPP1R26P1 HGNC:HGNC:42015 +100418742 CLUHP9 HGNC:HGNC:51572 +100418743 CCNL2P1 HGNC:HGNC:50855 +100418744 KRT8P46 HGNC:HGNC:39880 +100418745 CLUHP5 HGNC:HGNC:38471 +100418747 KRT8P35 HGNC:HGNC:39869 +100418748 KRT8P36 HGNC:HGNC:39870 +100418750 KRT8P42 HGNC:HGNC:39876 +100418751 GOLGA2P1 HGNC:HGNC:31052 +100418753 LOC100418753 - +100418754 CLUHP6 HGNC:HGNC:51571 +100418756 CLUHP11 HGNC:HGNC:51806 +100418759 LOC100418759 - +100418763 CCNT2P1 HGNC:HGNC:39178 +100418768 LOC100418768 - +100418769 KRT18P52 HGNC:HGNC:37888 +100418770 KRT18P26 HGNC:HGNC:33395 +100418774 PHBP4 HGNC:HGNC:8916 +100418779 KRT127P HGNC:HGNC:40019 +100418781 KRT8P39 HGNC:HGNC:39873 +100418792 KRT18P54 HGNC:HGNC:39425 +100418799 KRT8P38 HGNC:HGNC:39872 +100418804 PHBP8 HGNC:HGNC:39287 +100418811 KRT8P34 HGNC:HGNC:39868 +100418814 MTDHP1 HGNC:HGNC:52357 +100418815 PHBP10 HGNC:HGNC:39289 +100418819 IPO8P1 HGNC:HGNC:41955 +100418820 PHBP12 HGNC:HGNC:39291 +100418822 LOC100418822 - +100418828 KRT125P HGNC:HGNC:48875 +100418829 KRT18P60 HGNC:HGNC:48887 +100418832 MTDHP3 HGNC:HGNC:52359 +100418834 MTDHP4 HGNC:HGNC:52360 +100418835 MTDHP2 HGNC:HGNC:52358 +100418836 MTDHP5 HGNC:HGNC:52361 +100418837 PHBP2 HGNC:HGNC:8914 +100418843 PHBP13 HGNC:HGNC:39292 +100418848 LOC100418848 - +100418861 KRT43P HGNC:HGNC:48870 +100418862 LOC100418862 - +100418865 KRT18P61 HGNC:HGNC:48888 +100418868 LOC100418868 - +100418871 LOC100418871 - +100418874 LOC100418874 - +100418877 KRT18P7 HGNC:HGNC:20283 +100418881 NBEAP2 HGNC:HGNC:40003 +100418882 LOC100418882 - +100418883 LOC100418883 - +100418884 LOC100418884 - +100418885 LOC100418885 - +100418887 TAGLN2P1 HGNC:HGNC:21739 +100418888 LOC100418888 - +100418889 STX18P1 HGNC:HGNC:43995 +100418892 GYG2P2 HGNC:HGNC:39713 +100418897 NBEAP4 HGNC:HGNC:40009 +100418898 LOC100418898 - +100418902 TUBBP10 HGNC:HGNC:42344 +100418903 NBEAP5 HGNC:HGNC:40010 +100418904 NBEAP6 HGNC:HGNC:40011 +100418905 NBEAP3 HGNC:HGNC:40004 +100418906 LOC100418906 - +100418908 GLRX3P1 HGNC:HGNC:49787 +100418910 ACTG1P14 HGNC:HGNC:49751 +100418919 TNPO1P1 HGNC:HGNC:45120 +100418920 ACTG1P13 HGNC:HGNC:49058 +100418921 ACTG1P12 HGNC:HGNC:44496 +100418923 LOC100418923 - +100418924 ACTG1P18 HGNC:HGNC:51498 +100418928 LOC100418928 - +100418937 TUBB8P1 HGNC:HGNC:42182 +100418938 LOC100418938 - +100418939 LOC100418939 - +100418940 LOC100418940 - +100418942 PRDX4P2 HGNC:HGNC:43599 +100418943 PRDX2P3 HGNC:HGNC:44968 +100418949 PRDX4P1 HGNC:HGNC:43598 +100418951 ACTG1P15 HGNC:HGNC:51495 +100418955 PRDX3P4 HGNC:HGNC:44643 +100418956 LOC100418956 - +100418957 LOC100418957 - +100418959 LOC100418959 - +100418960 ACTG1P16 HGNC:HGNC:51496 +100418961 LOC100418961 - +100418964 TUBB6P1 HGNC:HGNC:42342 +100418965 LOC100418965 - +100418968 SNX2P1 HGNC:HGNC:41514 +100418972 SNX18P14 HGNC:HGNC:39622 +100418973 LOC100418973 - +100418974 TUBB4BP2 HGNC:HGNC:42183 +100418975 SNX18P3 HGNC:HGNC:39611 +100418976 SNX18P4 HGNC:HGNC:39612 +100418977 SNX18P5 HGNC:HGNC:39613 +100418980 SNX18P7 HGNC:HGNC:39615 +100418981 SNX18P8 HGNC:HGNC:39616 +100418983 NF1P12 HGNC:HGNC:51739 +100418986 LOC100418986 - +100418987 LOC100418987 - +100418988 LOC100418988 - +100418989 LOC100418989 - +100418990 LOC100418990 - +100418991 LOC100418991 - +100418992 LOC100418992 - +100418993 LOC100418993 - +100418997 LOC100418997 - +100418999 SNX18P1Y HGNC:HGNC:38442 +100419003 LOC100419003 - +100419004 SNX18P24 HGNC:HGNC:39632 +100419005 SNX18P25 HGNC:HGNC:39633 +100419006 NF1P1 HGNC:HGNC:7772 +100419007 TUBAP3 HGNC:HGNC:44568 +100419008 LOC100419008 - +100419014 LOC100419014 - +100419016 LOC100419016 - +100419017 LOC100419017 - +100419019 SNX18P15 HGNC:HGNC:39623 +100419020 SNX18P16 HGNC:HGNC:39624 +100419021 SNX18P18 HGNC:HGNC:39626 +100419022 SNX18P19 HGNC:HGNC:39627 +100419023 PDCL3P6 HGNC:HGNC:44507 +100419024 SNX18P17 HGNC:HGNC:39625 +100419025 SNX18P21 HGNC:HGNC:39629 +100419026 SNX18P20 HGNC:HGNC:39628 +100419027 SNX18P22 HGNC:HGNC:39630 +100419028 SNX25P1 HGNC:HGNC:41509 +100419029 NF1P4 HGNC:HGNC:7769 +100419031 PRDX3P1 HGNC:HGNC:39264 +100419033 LOC100419033 - +100419036 LOC100419036 - +100419037 LOC100419037 - +100419038 SNX18P26 HGNC:HGNC:39634 +100419040 SNX18P10 HGNC:HGNC:39618 +100419041 SNX18P12 HGNC:HGNC:39620 +100419042 SNX18P13 HGNC:HGNC:39621 +100419043 SNX18P11 HGNC:HGNC:39619 +100419045 LOC100419045 - +100419046 LOC100419046 - +100419047 SNX19P4 HGNC:HGNC:41510 +100419052 LOC100419052 - +100419053 LOC100419053 - +100419054 SAGE3P HGNC:HGNC:51338 +100419056 CLCN3P1 HGNC:HGNC:49775 +100419058 LOC100419058 - +100419059 LOC100419059 - +100419062 FOSL1P1 HGNC:HGNC:44055 +100419066 NUP35P1 HGNC:HGNC:52370 +100419068 PNLIPP1 HGNC:HGNC:45264 +100419069 ENO1P3 HGNC:HGNC:37944 +100419070 NUP210P3 HGNC:HGNC:42712 +100419073 LOC100419073 - +100419074 AK3P2 HGNC:HGNC:31099 +100419075 AK3P3 HGNC:HGNC:39062 +100419077 FCRL6P1 HGNC:HGNC:49448 +100419079 LOC100419079 - +100419081 DUXAP12 HGNC:HGNC:51813 +100419085 LOC100419085 - +100419092 LOC100419092 - +100419095 TXNL1P1 HGNC:HGNC:39459 +100419096 LOC100419096 - +100419098 ENO1P2 HGNC:HGNC:37943 +100419102 LOC100419102 - +100419108 LOC100419108 - +100419110 LOC100419110 - +100419140 LOC100419140 - +100419149 HCFC2P1 HGNC:HGNC:39815 +100419154 LOC100419154 - +100419158 SETP12 HGNC:HGNC:42931 +100419161 LOC100419161 - +100419170 LOC100419170 Ensembl:ENSG00000250771 +100419174 LOC100419174 - +100419178 SETP6 HGNC:HGNC:42925 +100419185 PDLIM1P4 HGNC:HGNC:48947 +100419187 SETP11 HGNC:HGNC:42930 +100419209 PRSS52P HGNC:HGNC:37322 +100419232 LOC100419232 - +100419238 LOC100419238 - +100419246 BTG3P1 HGNC:HGNC:51543 +100419257 LOC100419257 - +100419284 LOC100419284 - +100419293 LOC100419293 - +100419301 LOC100419301 - +100419307 LOC100419307 - +100419318 LOC100419318 - +100419319 LOC100419319 - +100419321 LOC100419321 - +100419324 BCL9P1 HGNC:HGNC:51328 +100419337 CENPIP1 HGNC:HGNC:39575 +100419353 LOC100419353 - +100419356 LOC100419356 - +100419366 LOC100419366 - +100419391 RPL21P135 HGNC:HGNC:44539 +100419392 RPL12P44 HGNC:HGNC:44603 +100419416 SRPK2P HGNC:HGNC:30303 +100419423 ASNSP4 HGNC:HGNC:39400 +100419426 PDLIM1P2 HGNC:HGNC:48945 +100419427 PDLIM1P3 HGNC:HGNC:48946 +100419436 LOC100419436 - +100419447 LOC100419447 - +100419451 LOC100419451 - +100419458 LOC100419458 - +100419471 RPS23P10 HGNC:HGNC:48342 +100419472 RPS23P9 HGNC:HGNC:48341 +100419477 RPL12P45 HGNC:HGNC:51937 +100419489 HDAC1P2 HGNC:HGNC:45191 +100419503 LOC100419503 - +100419506 LOC100419506 - +100419511 LOC100419511 - +100419512 LOC100419512 - +100419513 LOC100419513 - +100419515 LOC100419515 - +100419516 LOC100419516 - +100419520 LOC100419520 - +100419521 RPL21P136 HGNC:HGNC:49854 +100419525 LOC100419525 - +100419542 LOC100419542 - +100419545 LOC100419545 - +100419548 RPS27AP18 HGNC:HGNC:52299 +100419549 LOC100419549 - +100419552 LOC100419552 - +100419553 LOC100419553 - +100419554 ZNF92P1Y HGNC:HGNC:39553 +100419558 KARSP1 HGNC:HGNC:39207 +100419560 KARSP2 HGNC:HGNC:39208 +100419562 LOC100419562 - +100419565 LOC100419565 - +100419570 LOC100419570 - +100419572 LOC100419572 - +100419574 LOC100419574 - +100419579 LOC100419579 - +100419583 LOC100419583 - +100419595 HDAC1P1 HGNC:HGNC:45190 +100419599 RNF10P1 HGNC:HGNC:44472 +100419606 ZNF90P2 HGNC:HGNC:21687 +100419608 ZNF602P HGNC:HGNC:23313 +100419609 ZNF70P1 HGNC:HGNC:13846 +100419610 TYMSP1 HGNC:HGNC:52351 +100419613 LOC100419613 - +100419614 MIOXP1 HGNC:HGNC:50748 +100419615 LOC100419615 - +100419616 LOC100419616 - +100419617 LOC100419617 - +100419620 LOC100419620 - +100419621 LOC100419621 - +100419622 LOC100419622 - +100419624 LOC100419624 - +100419639 LOC100419639 - +100419641 LOC100419641 - +100419642 LOC100419642 - +100419643 LOC100419643 - +100419644 LOC100419644 - +100419645 LOC100419645 - +100419649 PRAMEF35P HGNC:HGNC:51896 +100419650 RPL23AP85 HGNC:HGNC:51576 +100419654 LOC100419654 - +100419668 LOC100419668 - +100419673 LOC100419673 - +100419678 LOC100419678 - +100419679 LOC100419679 - +100419680 LOC100419680 - +100419682 ZNF863P HGNC:HGNC:35156 +100419684 LOC100419684 - +100419685 LOC100419685 - +100419686 LOC100419686 - +100419687 RNF152P1 HGNC:HGNC:49743 +100419690 LOC100419690 - +100419691 LOC100419691 - +100419692 LOC100419692 - +100419693 LOC100419693 - +100419700 LOC100419700 - +100419701 LOC100419701 - +100419702 LOC100419702 - +100419704 LOC100419704 - +100419705 ZNF92P2 HGNC:HGNC:39554 +100419706 LOC100419706 - +100419707 LOC100419707 - +100419709 ZNF887P HGNC:HGNC:38700 +100419711 ZNF92P3 HGNC:HGNC:39555 +100419712 LOC100419712 - +100419713 LOC100419713 - +100419714 AHCYP6 HGNC:HGNC:44998 +100419715 LOC100419715 - +100419716 LOC100419716 - +100419717 SALL4P1 HGNC:HGNC:39818 +100419720 LOC100419720 - +100419721 LOC100419721 - +100419722 RNF19BPY HGNC:HGNC:38398 +100419724 ZNF736P8Y HGNC:HGNC:38406 +100419725 ZNF736P7Y HGNC:HGNC:38404 +100419726 ZNF736P9Y HGNC:HGNC:38408 +100419727 ZNF736P10Y HGNC:HGNC:38410 +100419728 ZNF886P HGNC:HGNC:38420 +100419729 ZNF884P HGNC:HGNC:38421 +100419730 ZNF736P11Y HGNC:HGNC:38426 +100419731 ZNF736P12Y HGNC:HGNC:38431 +100419732 ZNF736P6Y HGNC:HGNC:38440 +100419733 ZNF839P1 HGNC:HGNC:38455 +100419734 ZNF885P HGNC:HGNC:38456 +100419735 ZNF736P4Y HGNC:HGNC:38464 +100419737 LOC100419737 - +100419739 LOC100419739 - +100419741 LOC100419741 - +100419742 R3HDM2P1 HGNC:HGNC:44056 +100419743 DBET MIM:614865|HGNC:HGNC:43904|Ensembl:ENSG00000281591 +100419748 LOC100419748 - +100419750 LOC100419750 - +100419751 ZNF587P1 HGNC:HGNC:42438 +100419752 LOC100419752 - +100419755 LOC100419755 - +100419756 ZNF968P HGNC:HGNC:44091 +100419758 PKMP3 HGNC:HGNC:44245 +100419761 LOC100419761 - +100419762 LOC100419762 - +100419763 LOC100419763 - +100419764 GARSP1 HGNC:HGNC:50480 +100419768 LOC100419768 - +100419772 LOC100419772 - +100419773 LOC100419773 - +100419774 LOC100419774 - +100419775 LOC100419775 - +100419776 ZNF619P1 HGNC:HGNC:50784 +100419777 RNF138P2 HGNC:HGNC:50775 +100419779 LOC100419779 - +100419780 ZNF722P HGNC:HGNC:22571 +100419781 LOC100419781 - +100419782 LOC100419782 - +100419783 LOC100419783 - +100419784 LOC100419784 - +100419786 LOC100419786 - +100419788 RNF19BPX HGNC:HGNC:38484 +100419790 LOC100419790 - +100419791 LOC100419791 - +100419792 LOC100419792 - +100419793 BEND7P1 HGNC:HGNC:51362 +100419794 LOC100419794 - +100419795 LOC100419795 - +100419796 LOC100419796 - +100419798 LOC100419798 - +100419799 LOC100419799 - +100419801 LOC100419801 - +100419802 LOC100419802 - +100419803 LOC100419803 - +100419806 LOC100419806 - +100419811 LOC100419811 - +100419812 LOC100419812 - +100419814 LOC100419814 - +100419815 LOC100419815 - +100419816 LOC100419816 - +100419821 CSNK1G2P1 HGNC:HGNC:49739 +100419824 LOC100419824 - +100419825 LOC100419825 - +100419827 ZKSCAN7P1 HGNC:HGNC:49867 +100419829 RARSP1 HGNC:HGNC:49893 +100419830 LOC100419830 - +100419831 LOC100419831 - +100419833 LOC100419833 - +100419834 LOC100419834 - +100419835 LOC100419835 - +100419836 LOC100419836 - +100419839 LOC100419839 - +100419840 LOC100419840 - +100419841 LOC100419841 - +100419842 LOC100419842 - +100419844 LOC100419844 - +100419845 LOC100419845 - +100419847 LOC100419847 - +100419848 LOC100419848 - +100419851 LOC100419851 - +100419852 LOC100419852 - +100419853 LOC100419853 - +100419854 ZNF646P1 HGNC:HGNC:39749 +100419855 SALL4P4 HGNC:HGNC:39821 +100419859 LOC100419859 - +100419861 LOC100419861 - +100419862 LOC100419862 - +100419863 LOC100419863 - +100419866 ZNF444P1 HGNC:HGNC:35157 +100419867 ZNF101P1 HGNC:HGNC:44940 +100419868 ZNF33BP1 HGNC:HGNC:44975 +100419870 LOC100419870 - +100419872 LOC100419872 - +100419873 ZNF519P1 HGNC:HGNC:50785 +100419875 FNBP1P2 HGNC:HGNC:44527 +100419877 LOC100419877 - +100419878 LOC100419878 - +100419880 KIF3AP1 HGNC:HGNC:52811 +100419882 LOC100419882 - +100419883 YAP1P3 HGNC:HGNC:43890 +100419888 LOC100419888 - +100419890 LOC100419890 - +100419891 LOC100419891 - +100419892 LOC100419892 - +100419893 ZNF415P1 HGNC:HGNC:49869 +100419894 LOC100419894 - +100419895 ZNF971P HGNC:HGNC:51848 +100419896 LOC100419896 - +100419901 LOC100419901 - +100419903 RWDD4P1 HGNC:HGNC:23753 +100419906 LOC100419906 - +100419907 LOC100419907 - +100419908 LOC100419908 - +100419909 YAP1P2 HGNC:HGNC:38017 +100419911 LOC100419911 - +100419912 LOC100419912 - +100419913 LOC100419913 - +100419915 LOC100419915 - +100419916 CDK8P1 HGNC:HGNC:18995 +100419917 LOC100419917 - +100419920 LOC100419920 - +100419921 LOC100419921 - +100419923 LOC100419923 - +100419924 LOC100419924 - +100419925 LOC100419925 - +100419926 LOC100419926 - +100419928 LOC100419928 - +100419929 LOC100419929 - +100419930 CENPUP2 HGNC:HGNC:49890 +100419932 LOC100419932 - +100419935 LOC100419935 - +100419945 TRIM51DP HGNC:HGNC:43969 +100419947 HMGB1P21 HGNC:HGNC:39106 +100419948 HMGB3P17 HGNC:HGNC:39309 +100419949 HMGB3P3 HGNC:HGNC:39102 +100419950 HMGB1P35 HGNC:HGNC:39175 +100419951 LOC100419951 - +100419952 LOC100419952 - +100419955 SDAD1P4 HGNC:HGNC:39261 +100419956 LOC100419956 - +100419957 LOC100419957 - +100419959 LOC100419959 - +100419960 LOC100419960 - +100419962 ANKRD54P1 HGNC:HGNC:39214 +100419963 YY1P1 HGNC:HGNC:45094 +100419964 RSU1P3 HGNC:HGNC:44392 +100419966 LOC100419966 - +100419967 LOC100419967 - +100419968 HMGB1P36 HGNC:HGNC:39176 +100419969 LOC100419969 - +100419971 PRELID1P2 HGNC:HGNC:43887 +100419972 HMGB1P39 HGNC:HGNC:39186 +100419974 HMGB1P17 HGNC:HGNC:39099 +100419975 LOC100419975 - +100419977 LOC100419977 - +100419978 HMGB1P46 HGNC:HGNC:39279 +100419979 HMGB1P19 HGNC:HGNC:39101 +100419980 LOC100419980 - +100419984 LOC100419984 - +100419985 LOC100419985 - +100419986 LOC100419986 - +100419987 LOC100419987 - +100419989 THUMPD3P1 HGNC:HGNC:50793 +100419991 LOC100419991 - +100419995 HMGB1P32 HGNC:HGNC:39123 +100419996 HMGB1P11 HGNC:HGNC:13316 +100420002 LOC100420002 - +100420003 E2F3P2 HGNC:HGNC:3117 +100420004 HSPA8P10 HGNC:HGNC:44925 +100420005 FAR2P4 HGNC:HGNC:49286 +100420006 LOC100420006 - +100420008 LOC100420008 - +100420011 LOC100420011 - +100420012 ARF1P2 HGNC:HGNC:39883 +100420013 HMGB1P49 HGNC:HGNC:39282 +100420015 HMGB3P29 HGNC:HGNC:39321 +100420018 LOC100420018 - +100420019 LOC100420019 - +100420020 LOC100420020 - +100420021 LOC100420021 - +100420022 LOC100420022 - +100420024 LOC100420024 - +100420025 LOC100420025 - +100420027 LOC100420027 - +100420028 HSPA8P4 HGNC:HGNC:44919 +100420030 MORF4L1P4 HGNC:HGNC:39257 +100420033 HMGB3P7 HGNC:HGNC:39299 +100420035 LOC100420035 - +100420036 RFPL4AP4 HGNC:HGNC:45140 +100420038 HSPA8P12 HGNC:HGNC:44927 +100420041 HMGB1P43 HGNC:HGNC:39191 +100420042 CARSP1 HGNC:HGNC:50477 +100420043 CACYBPP1 HGNC:HGNC:45122 +100420044 HMGB1P7 HGNC:HGNC:39096 +100420046 PRELID1P3 HGNC:HGNC:43888 +100420047 RAD51AP1P1 HGNC:HGNC:49646 +100420048 LOC100420048 - +100420049 HSPA8P19 HGNC:HGNC:44935 +100420050 LOC100420050 - +100420051 HSPA8P15 HGNC:HGNC:44930 +100420052 LOC100420052 - +100420053 LOC100420053 - +100420054 LOC100420054 - +100420055 RFPL4AP7 HGNC:HGNC:45143 +100420057 LOC100420057 - +100420058 RFPL4AP5 HGNC:HGNC:45144 +100420059 RFPL4AP2 HGNC:HGNC:45145 +100420060 LOC100420060 - +100420061 LOC100420061 - +100420062 LOC100420062 - +100420063 HMGB1P24 HGNC:HGNC:39115 +100420064 LOC100420064 - +100420066 LOC100420066 - +100420067 LOC100420067 - +100420072 EI24P4 HGNC:HGNC:44589 +100420073 LOC100420073 - +100420074 LOC100420074 - +100420075 PLCE1P1 HGNC:HGNC:51906 +100420080 HSPA8P7 HGNC:HGNC:44922 +100420083 LOC100420083 - +100420084 LOC100420084 - +100420089 LOC100420089 - +100420092 LOC100420092 - +100420095 LOC100420095 - +100420096 LOC100420096 - +100420097 LOC100420097 - +100420098 LOC100420098 - +100420100 HMGB1P34 HGNC:HGNC:23342 +100420103 LOC100420103 - +100420108 LOC100420108 - +100420109 LOC100420109 - +100420110 LOC100420110 - +100420113 KLF4P1 HGNC:HGNC:49738 +100420114 LOC100420114 - +100420116 LOC100420116 - +100420117 LOC100420117 - +100420118 LOC100420118 - +100420119 LOC100420119 - +100420121 LOC100420121 - +100420122 LOC100420122 - +100420123 LOC100420123 - +100420127 LOC100420127 - +100420130 LOC100420130 - +100420133 HSPA8P2 HGNC:HGNC:39806 +100420143 HSPA8P3 HGNC:HGNC:44918 +100420144 LOC100420144 - +100420149 BECN1P2 HGNC:HGNC:51330 +100420155 RPL7L1P2 HGNC:HGNC:39484 +100420158 FTLP16 HGNC:HGNC:37966 +100420159 RRM2P3 HGNC:HGNC:10455 +100420162 LOC100420162 - +100420166 LOC100420166 - +100420170 LOC100420170 - +100420171 LOC100420171 - +100420172 LOC100420172 - +100420174 LOC100420174 - +100420175 LOC100420175 - +100420177 LOC100420177 - +100420178 E2F6P3 HGNC:HGNC:51451 +100420180 DBF4P2 HGNC:HGNC:45060 +100420186 LOC100420186 - +100420187 LOC100420187 - +100420189 SEPHS1P3 HGNC:HGNC:42163 +100420190 SEPHS2P1 HGNC:HGNC:42165 +100420198 LUC7L3P1 HGNC:HGNC:39790 +100420200 RPL7L1P12 HGNC:HGNC:39811 +100420201 RPL7L1P6 HGNC:HGNC:39488 +100420203 CICP16 HGNC:HGNC:38550 +100420205 LOC100420205 - +100420206 RPL36AP55 HGNC:HGNC:44939 +100420207 MED28P1 HGNC:HGNC:45078 +100420211 LOC100420211 - +100420213 RBM11P1 HGNC:HGNC:43743 +100420214 LOC100420214 - +100420215 LOC100420215 - +100420216 ALOXE3P1 HGNC:HGNC:44238 +100420223 RNMTL1P2 HGNC:HGNC:44906 +100420224 CICP12 HGNC:HGNC:37905 +100420226 LOC100420226 - +100420228 LOC100420228 - +100420230 LOC100420230 - +100420245 LOC100420245 - +100420247 LOC100420247 - +100420250 LOC100420250 - +100420251 LOC100420251 - +100420252 LOC100420252 - +100420253 CTBP2P8 HGNC:HGNC:45200 +100420254 LOC100420254 - +100420255 LOC100420255 - +100420257 CICP27 HGNC:HGNC:48835 +100420258 PLA2G12AP1 HGNC:HGNC:39248 +100420259 GDI2P2 HGNC:HGNC:37976 +100420260 NOTCH2P1 HGNC:HGNC:44253 +100420262 LOC100420262 - +100420263 CICP21 HGNC:HGNC:48836 +100420267 LOC100420267 - +100420269 FBP2P1 HGNC:HGNC:49924 +100420273 LOC100420273 - +100420275 PRELID3BP4 HGNC:HGNC:49066 +100420277 PRELID3BP9 HGNC:HGNC:49071 +100420281 PLA2G12AP2 HGNC:HGNC:39249 +100420287 SEC63P2 HGNC:HGNC:41954 +100420289 LOC100420289 - +100420292 SEPHS1P2 HGNC:HGNC:42162 +100420293 CICP9 HGNC:HGNC:37758 +100420295 RNMTL1P1 HGNC:HGNC:44905 +100420298 LOC100420298 - +100420300 FTH1P23 HGNC:HGNC:37641 +100420303 FTH1P26 HGNC:HGNC:37644 +100420304 LOC100420304 - +100420305 LOC100420305 - +100420307 NTAN1P2 HGNC:HGNC:45262 +100420308 ITM2BP1 HGNC:HGNC:20919 +100420311 LOC100420311 - +100420317 LOC100420317 - +100420318 LOC100420318 - +100420320 LOC100420320 - +100420321 LOC100420321 - +100420322 LOC100420322 - +100420323 LOC100420323 - +100420324 LOC100420324 - +100420325 LOC100420325 - +100420326 LOC100420326 - +100420331 LOC100420331 - +100420334 LOC100420334 - +100420336 LOC100420336 - +100420338 LOC100420338 - +100420339 LOC100420339 - +100420341 SEC63P1 HGNC:HGNC:41953 +100420342 CHIAP1 HGNC:HGNC:44462 +100420343 LOC100420343 - +100420347 LOC100420347 - +100420351 LOC100420351 - +100420353 LOC100420353 - +100420354 ECM1P1 HGNC:HGNC:49736 +100420356 NTAN1P3 HGNC:HGNC:45263 +100420358 BUD13P1 HGNC:HGNC:51560 +100420359 RPA2P3 HGNC:HGNC:45118 +100420362 TRIM60P1Y HGNC:HGNC:38403 +100420363 TRIM60P2Y HGNC:HGNC:38405 +100420364 TRIM60P3Y HGNC:HGNC:38409 +100420367 TRIM60P4Y HGNC:HGNC:38425 +100420368 TRIM60P5Y HGNC:HGNC:38430 +100420369 TRIM60P6Y HGNC:HGNC:38432 +100420370 TRIM60P7Y HGNC:HGNC:38433 +100420373 TRIM60P8Y HGNC:HGNC:38458 +100420374 TRIM60P9Y HGNC:HGNC:38459 +100420376 TRIM60P10Y HGNC:HGNC:38462 +100420377 TRIM60P11Y HGNC:HGNC:38463 +100420378 TRIM60P12Y HGNC:HGNC:38465 +100420385 LOC100420385 - +100420386 LOC100420386 - +100420389 NTAN1P1 HGNC:HGNC:45261 +100420392 BTBD7P2 HGNC:HGNC:44876 +100420393 TPMTP2 HGNC:HGNC:44565 +100420394 LOC100420394 - +100420401 BTBD10P2 HGNC:HGNC:51541 +100420403 LOC100420403 - +100420404 LOC100420404 - +100420405 TRIM60P15 HGNC:HGNC:38487 +100420406 IRF5P1 HGNC:HGNC:41981 +100420408 LOC100420408 - +100420410 H3F3BP2 HGNC:HGNC:42979 +100420412 TRIM60P16 HGNC:HGNC:38488 +100420413 LOC100420413 - +100420414 TRIM60P17 HGNC:HGNC:38489 +100420415 TRIM60P18 HGNC:HGNC:38490 +100420418 LOC100420418 - +100420420 LOC100420420 - +100420423 LOC100420423 - +100420424 LOC100420424 - +100420428 LOC100420428 - +100420429 LOC100420429 - +100420430 LOC100420430 - +100420432 LOC100420432 - +100420434 STIP1P1 HGNC:HGNC:49552 +100420435 LOC100420435 - +100420436 STIP1P2 HGNC:HGNC:49553 +100420437 LOC100420437 - +100420438 LOC100420438 - +100420439 LOC100420439 - +100420440 LOC100420440 - +100420442 LOC100420442 - +100420446 LOC100420446 - +100420449 LOC100420449 - +100420450 SERBP1P6 HGNC:HGNC:44635 +100420457 NT5CP3 HGNC:HGNC:39789 +100420458 TATDN2P3 HGNC:HGNC:39256 +100420462 LDHAL6EP HGNC:HGNC:44241 +100420464 LOC100420464 - +100420466 LOC100420466 - +100420467 LOC100420467 - +100420471 ARL4AP4 HGNC:HGNC:52373 +100420473 DUSP12P1 HGNC:HGNC:49059 +100420476 SSR1P1 HGNC:HGNC:39273 +100420477 LDHAL6FP HGNC:HGNC:44240 +100420480 LOC100420480 - +100420482 LOC100420482 - +100420484 THEMIS3P HGNC:HGNC:49196 +100420489 LOC100420489 - +100420494 LOC100420494 - +100420499 LOC100420499 - +100420500 LOC100420500 - +100420501 YRDCP1 HGNC:HGNC:39919 +100420502 CDCA4P1 HGNC:HGNC:49770 +100420503 EGLN3P1 HGNC:HGNC:49857 +100420505 ADAM1B HGNC:HGNC:44366 +100420508 LDHAL6DP HGNC:HGNC:44239 +100420509 XIAPP2 HGNC:HGNC:52376 +100420510 LOC100420510 - +100420512 RPEP1 HGNC:HGNC:44520 +100420513 LOC100420513 - +100420514 LOC100420514 - +100420515 LOC100420515 - +100420519 RANP8 HGNC:HGNC:39863 +100420520 MOCS3P2 HGNC:HGNC:39444 +100420526 PAWRP1 HGNC:HGNC:45201 +100420527 RBBP4P2 HGNC:HGNC:42369 +100420528 LOC100420528 - +100420530 LOC100420530 - +100420531 LOC100420531 - +100420532 LOC100420532 - +100420534 LOC100420534 - +100420535 PAWRP2 HGNC:HGNC:45202 +100420536 LOC100420536 - +100420539 LOC100420539 - +100420540 LOC100420540 - +100420541 LOC100420541 - +100420545 LOC100420545 - +100420546 GTF2IP5 HGNC:HGNC:51717 +100420547 LOC100420547 - +100420548 LOC100420548 - +100420549 LOC100420549 - +100420551 LOC100420551 - +100420552 RBBP8P1 HGNC:HGNC:39583 +100420555 RPEP3 HGNC:HGNC:44522 +100420556 CPT2P1 HGNC:HGNC:49538 +100420557 NSRP1P1 HGNC:HGNC:38087 +100420558 CDCA4P3 HGNC:HGNC:49772 +100420563 LOC100420563 - +100420567 PGAM1P6 HGNC:HGNC:42453 +100420568 VDAC1P13 HGNC:HGNC:50515 +100420569 LOC100420569 - +100420571 LOC100420571 - +100420572 LOC100420572 - +100420574 VDAC2P4 HGNC:HGNC:51932 +100420575 LOC100420575 - +100420576 LOC100420576 - +100420580 LOC100420580 - +100420583 LOC100420583 - +100420584 LOC100420584 - +100420586 LOC100420586 - +100420587 LOC100420587 Ensembl:ENSG00000283403 +100420588 CCDC58P5 HGNC:HGNC:45028 +100420589 LRRC6P1 HGNC:HGNC:51151 +100420590 RPEP6 HGNC:HGNC:44525 +100420591 OSBPL9P3 HGNC:HGNC:48733 +100420593 GTF3AP4 HGNC:HGNC:49747 +100420607 RBBP8P2 HGNC:HGNC:39584 +100420608 RPP40P2 HGNC:HGNC:39770 +100420611 LOC100420611 - +100420612 ERP29P1 HGNC:HGNC:24625 +100420613 LRRC34P2 HGNC:HGNC:49888 +100420615 LOC100420615 - +100420617 LOC100420617 - +100420618 LOC100420618 - +100420620 LOC100420620 - +100420621 MTAPP2 HGNC:HGNC:42443 +100420627 GSTA8P HGNC:HGNC:49903 +100420631 BTRCP1 HGNC:HGNC:51546 +100420633 PGAM1P10 HGNC:HGNC:42457 +100420638 LOC100420638 - +100420641 LOC100420641 - +100420642 LOC100420642 - +100420644 LOC100420644 - +100420647 LOC100420647 - +100420648 LOC100420648 - +100420650 PGAM1P7 HGNC:HGNC:42454 +100420653 LOC100420653 - +100420656 QTRT1P1 HGNC:HGNC:39179 +100420658 LOC100420658 - +100420660 PGAM1P11 HGNC:HGNC:42464 +100420665 RPEP4 HGNC:HGNC:44523 +100420666 LOC100420666 - +100420667 LOC100420667 - +100420668 LOC100420668 - +100420669 LOC100420669 - +100420670 NPAP1P8 HGNC:HGNC:51474 +100420671 NPAP1P5 HGNC:HGNC:45022 +100420673 LOC100420673 - +100420678 CCDC150P1 HGNC:HGNC:50280 +100420679 LOC100420679 - +100420680 LOC100420680 - +100420681 PGAM1P9 HGNC:HGNC:42456 +100420683 LOC100420683 - +100420689 CASC4P1 HGNC:HGNC:39251 +100420693 LOC100420693 - +100420695 ABT1P1 HGNC:HGNC:39557 +100420707 LOC100420707 - +100420710 TPST2P1 HGNC:HGNC:44425 +100420711 LOC100420711 - +100420734 RAB5CP1 HGNC:HGNC:45104 +100420737 NEFMP1 HGNC:HGNC:45030 +100420738 LOC100420738 - +100420741 LOC100420741 - +100420742 LOC100420742 - +100420743 LOC100420743 - +100420746 LOC100420746 - +100420748 LOC100420748 - +100420752 SRP72P1 HGNC:HGNC:31095 +100420754 SOCS5P1 HGNC:HGNC:44597 +100420758 LOC100420758 - +100420759 LOC100420759 - +100420760 LOC100420760 - +100420763 CKAP2P1 HGNC:HGNC:49923 +100420765 LOC100420765 - +100420769 LOC100420769 - +100420770 LOC100420770 - +100420772 LOC100420772 - +100420774 LOC100420774 - +100420775 LOC100420775 - +100420776 CNTNAP3P6 HGNC:HGNC:49583 +100420777 CNTNAP3P7 HGNC:HGNC:49585 +100420778 LOC100420778 - +100420779 LOC100420779 - +100420784 C2orf27AP3 HGNC:HGNC:50418 +100420785 CNTNAP3P8 HGNC:HGNC:49586 +100420786 CNTNAP3P5 HGNC:HGNC:49588 +100420787 CNTNAP3P1 HGNC:HGNC:49591 +100420788 LOC100420788 - +100420789 LOC100420789 - +100420790 LOC100420790 - +100420792 NDFIP1P1 HGNC:HGNC:49866 +100420794 LOC100420794 - +100420797 LOC100420797 - +100420798 LOC100420798 - +100420800 LOC100420800 - +100420801 LOC100420801 - +100420802 LOC100420802 - +100420803 LOC100420803 - +100420804 LOC100420804 - +100420811 C2orf27AP1 HGNC:HGNC:38413 +100420818 LOC100420818 - +100420821 LOC100420821 - +100420827 NPAP1P1 HGNC:HGNC:45018 +100420828 LOC100420828 - +100420829 NPAP1P2 HGNC:HGNC:45019 +100420830 NPAP1P3 HGNC:HGNC:45020 +100420831 LOC100420831 - +100420832 LOC100420832 - +100420833 FGFR3P4 HGNC:HGNC:37949 +100420834 SRRM1P2 HGNC:HGNC:38163 +100420839 LOC100420839 - +100420841 KATNBL1P5 HGNC:HGNC:49055 +100420843 KNOP1P4 HGNC:HGNC:48922 +100420845 LOC100420845 - +100420848 LOC100420848 - +100420850 LOC100420850 - +100420851 LOC100420851 - +100420852 LOC100420852 - +100420853 LOC100420853 - +100420854 SPDYE22P HGNC:HGNC:51518 +100420859 C2orf69P4 HGNC:HGNC:51803 +100420863 LOC100420863 - +100420864 LOC100420864 - +100420869 LOC100420869 - +100420872 LOC100420872 - +100420875 FAM204BP HGNC:HGNC:42011 +100420877 SLC25A39P1 HGNC:HGNC:43859 +100420878 LOC100420878 - +100420879 LOC100420879 - +100420880 LOC100420880 - +100420881 FGFR3P6 HGNC:HGNC:37951 +100420885 LOC100420885 - +100420886 RNFT1P1 HGNC:HGNC:44387 +100420887 LOC100420887 - +100420888 LOC100420888 - +100420889 LOC100420889 - +100420890 LOC100420890 - +100420892 LOC100420892 - +100420893 LOC100420893 - +100420895 LOC100420895 - +100420896 LOC100420896 - +100420897 LOC100420897 - +100420898 KNOP1P2 HGNC:HGNC:48920 +100420899 LOC100420899 - +100420900 FAM213AP1 HGNC:HGNC:52407 +100420901 HAUS8P1 HGNC:HGNC:43766 +100420902 LOC100420902 - +100420904 LOC100420904 - +100420907 LOC100420907 - +100420909 TMEM251P1 HGNC:HGNC:52396 +100420910 PRMT1P1 HGNC:HGNC:49611 +100420911 LOC100420911 - +100420916 FAM204CP HGNC:HGNC:42012 +100420919 KATNBL1P1 HGNC:HGNC:39724 +100420920 ZDHHC4P1 HGNC:HGNC:39443 +100420921 AMMECR1LP1 HGNC:HGNC:39809 +100420924 RNF6P1 HGNC:HGNC:39922 +100420925 LOC100420925 - +100420926 ZEB2P1 HGNC:HGNC:33346 +100420927 PRMT5P1 HGNC:HGNC:32524 +100420928 LOC100420928 - +100420929 LOC100420929 - +100420930 LOC100420930 - +100420939 LOC100420939 - +100420940 LOC100420940 - +100420941 BTN1A1P1 HGNC:HGNC:51545 +100420944 LOC100420944 - +100420946 KATNBL1P3 HGNC:HGNC:49053 +100420948 LOC100420948 - +100420949 LOC100420949 - +100420950 MRPL37P1 HGNC:HGNC:31003 +100420951 LOC100420951 - +100420952 FGFR3P5 HGNC:HGNC:37950 +100420954 LOC100420954 - +100420955 LOC100420955 - +100420957 LOC100420957 - +100420958 LOC100420958 - +100420963 FAM204DP HGNC:HGNC:42013 +100420966 LOC100420966 - +100420967 LOC100420967 - +100420968 LYARP1 HGNC:HGNC:50747 +100420972 ZFYVE9P2 HGNC:HGNC:39046 +100420975 GMCL1P2 HGNC:HGNC:42863 +100420981 LOC100420981 - +100420982 LOC100420982 - +100420983 LOC100420983 - +100420990 LOC100420990 - +100421002 HAVCR1P2 HGNC:HGNC:44035 +100421006 LOC100421006 - +100421008 SLC9B1P3 HGNC:HGNC:43582 +100421009 LOC100421009 - +100421010 LOC100421010 - +100421018 AMZ2P2 HGNC:HGNC:38072 +100421022 LOC100421022 - +100421023 LOC100421023 - +100421028 LOC100421028 - +100421029 LOC100421029 - +100421031 LOC100421031 - +100421039 LOC100421039 - +100421043 LOC100421043 - +100421045 BCAS2P2 HGNC:HGNC:39595 +100421046 SOD2P1 HGNC:HGNC:45268 +100421047 RBMX2P3 HGNC:HGNC:39925 +100421053 RIPPLY3P1 HGNC:HGNC:23340 +100421055 ZMYND19P1 HGNC:HGNC:44540 +100421057 GSTM3P2 HGNC:HGNC:38006 +100421058 PABPC1P11 HGNC:HGNC:37993 +100421061 LOC100421061 - +100421064 LOC100421064 - +100421071 LOC100421071 - +100421072 COQ10BP2 HGNC:HGNC:44913 +100421074 LOC100421074 - +100421075 RCC2P2 HGNC:HGNC:38419 +100421087 LOC100421087 - +100421090 RCC2P4 HGNC:HGNC:42380 +100421091 LOC100421091 - +100421092 LOC100421092 - +100421093 LOC100421093 - +100421094 LOC100421094 - +100421096 NCAPGP1 HGNC:HGNC:51904 +100421097 ALG1L12P HGNC:HGNC:44381 +100421100 LOC100421100 - +100421108 LOC100421108 - +100421109 LOC100421109 - +100421110 LOC100421110 - +100421113 CROCCP4 HGNC:HGNC:43864 +100421114 CROCCP5 HGNC:HGNC:43865 +100421116 LOC100421116 - +100421121 LOC100421121 - +100421122 LOC100421122 - +100421123 PGBD4P5 HGNC:HGNC:44070 +100421125 SMC4P1 HGNC:HGNC:51919 +100421126 LOC100421126 - +100421129 IFNL3P1 HGNC:HGNC:44483 +100421130 LOC100421130 - +100421131 RCC2P6 HGNC:HGNC:42382 +100421133 PGAM5P1 HGNC:HGNC:42467 +100421136 PGBD4P3 HGNC:HGNC:44068 +100421137 DPPA2P1 HGNC:HGNC:38448 +100421141 LOC100421141 - +100421142 LOC100421142 - +100421143 ELL2P2 HGNC:HGNC:39344 +100421146 PGBD4P4 HGNC:HGNC:44076 +100421148 NCAPGP2 HGNC:HGNC:51905 +100421150 COQ10BP1 HGNC:HGNC:44912 +100421153 DLEC1P1 HGNC:HGNC:44545 +100421154 LOC100421154 - +100421156 DPPA4P1 HGNC:HGNC:44903 +100421158 LOC100421158 - +100421160 LOC100421160 - +100421161 LOC100421161 - +100421165 LOC100421165 - +100421166 LOC100421166 - +100421167 SCML2P1 HGNC:HGNC:44329 +100421169 LOC100421169 - +100421171 LOC100421171 - +100421172 SCML2P2 HGNC:HGNC:44330 +100421173 LOC100421173 - +100421174 LOC100421174 - +100421175 NCAPD2P1 HGNC:HGNC:43831 +100421177 TDGF1P1 HGNC:HGNC:42350 +100421178 PGAM4P1 HGNC:HGNC:42465 +100421179 LOC100421179 - +100421180 PGBD4P6 HGNC:HGNC:44071 +100421182 PGBD4P7 HGNC:HGNC:44074 +100421184 LOC100421184 - +100421185 PGBD4P8 HGNC:HGNC:44075 +100421188 GAPDHP57 HGNC:HGNC:38563 +100421189 GAPDHP49 HGNC:HGNC:38555 +100421194 PDK1P1 HGNC:HGNC:49808 +100421197 LOC100421197 - +100421198 LAMP1P1 HGNC:HGNC:6500 +100421201 LOC100421201 - +100421202 LOC100421202 - +100421204 LOC100421204 - +100421207 LOC100421207 - +100421217 USP9YP5 HGNC:HGNC:38418 +100421219 USP9YP8 HGNC:HGNC:38424 +100421220 USP9YP9 HGNC:HGNC:38435 +100421222 USP9YP10 HGNC:HGNC:38454 +100421224 USP9YP11 HGNC:HGNC:38460 +100421226 RABEPKP1 HGNC:HGNC:39791 +100421228 PGBD4P2 HGNC:HGNC:44077 +100421232 GAPDHP56 HGNC:HGNC:38562 +100421235 LOC100421235 - +100421236 GAPDHP50 HGNC:HGNC:38556 +100421238 LOC100421238 - +100421239 FANCD2P1 HGNC:HGNC:44487 +100421245 NIP7P3 HGNC:HGNC:45182 +100421246 LOC100421246 - +100421248 LOC100421248 - +100421250 LOC100421250 - +100421256 LOC100421256 - +100421257 LOC100421257 - +100421258 LOC100421258 - +100421259 LOC100421259 - +100421267 LOC100421267 - +100421269 LOC100421269 - +100421271 GAPDHP51 HGNC:HGNC:38557 +100421273 LOC100421273 - +100421279 LOC100421279 - +100421281 LOC100421281 - +100421287 LOC100421287 - +100421288 LOC100421288 - +100421289 LOC100421289 - +100421292 LOC100421292 - +100421293 LOC100421293 - +100421294 LOC100421294 - +100421295 PRPS1P2 HGNC:HGNC:9464 +100421296 SRSF11P1 HGNC:HGNC:49884 +100421300 LOC100421300 - +100421303 LOC100421303 - +100421306 LOC100421306 - +100421307 DDX43P1 HGNC:HGNC:50780 +100421308 LOC100421308 - +100421309 LOC100421309 - +100421311 BRCC3P1 HGNC:HGNC:51444 +100421313 GAPDHP52 HGNC:HGNC:38558 +100421318 GAPDHP53 HGNC:HGNC:38559 +100421319 GAPDHP54 HGNC:HGNC:38560 +100421323 HNRNPRP3 HGNC:HGNC:44909 +100421324 GAPDHP55 HGNC:HGNC:38561 +100421328 DDX50P2 HGNC:HGNC:18975 +100421330 LOC100421330 - +100421331 SAMD11P1 HGNC:HGNC:44473 +100421332 LOC100421332 - +100421336 LOC100421336 - +100421338 CNOT7P1 HGNC:HGNC:44248 +100421340 FNDC3CP HGNC:HGNC:35452 +100421341 UBE2V2P3 HGNC:HGNC:44891 +100421343 LOC100421343 - +100421344 LOC100421344 - +100421347 LOC100421347 - +100421349 LOC100421349 - +100421350 TCEA1P4 HGNC:HGNC:31091 +100421351 HNRNPA1P14 HGNC:HGNC:39132 +100421353 HNRNPA1P15 HGNC:HGNC:39133 +100421354 HNRNPRP2 HGNC:HGNC:44908 +100421357 HNRNPA3P7 HGNC:HGNC:48496 +100421358 LOC100421358 - +100421361 LOC100421361 - +100421362 LOC100421362 - +100421363 ANKRD20A17P HGNC:HGNC:43608 +100421364 LOC100421364 - +100421368 LOC100421368 - +100421369 DDX20P1 HGNC:HGNC:44673 +100421371 DDX10P1 HGNC:HGNC:44960 +100421372 LOC100421372 - +100421374 MPRIPP1 HGNC:HGNC:44594 +100421376 HNRNPA1P17 HGNC:HGNC:39135 +100421378 HNRNPA1P77 HGNC:HGNC:48807 +100421379 HNRNPA1P37 HGNC:HGNC:48766 +100421384 HNRNPA1P38 HGNC:HGNC:48767 +100421385 LOC100421385 - +100421386 LOC100421386 - +100421387 LOC100421387 - +100421389 HNRNPA1P9 HGNC:HGNC:39127 +100421390 EIF5P1 HGNC:HGNC:51465 +100421391 EIF5P2 HGNC:HGNC:51466 +100421395 HNRNPA3P12 HGNC:HGNC:48758 +100421397 HNRNPA1P68 HGNC:HGNC:48798 +100421398 HNRNPA1P54 HGNC:HGNC:48784 +100421399 HNRNPA1P46 HGNC:HGNC:48776 +100421400 LOC100421400 - +100421401 LOC100421401 - +100421402 LOC100421402 - +100421404 LOC100421404 - +100421409 LOC100421409 - +100421413 HNRNPA3P10 HGNC:HGNC:48756 +100421414 LOC100421414 - +100421415 HNRNPA3P9 HGNC:HGNC:48755 +100421417 LOC100421417 - +100421419 LOC100421419 - +100421420 TPT1P5 HGNC:HGNC:49296 +100421422 ANKRD20A10P HGNC:HGNC:39707 +100421424 HNRNPA1P29 HGNC:HGNC:39547 +100421427 ANKRD20A16P HGNC:HGNC:43607 +100421428 RNGTTP1 HGNC:HGNC:39652 +100421429 RTEL1P1 HGNC:HGNC:44213 +100421430 HNRNPA1P74 HGNC:HGNC:48804 +100421431 HNRNPA3P11 HGNC:HGNC:48757 +100421432 HNRNPA1P44 HGNC:HGNC:48774 +100421433 HNRNPA1P71 HGNC:HGNC:48801 +100421436 UBE2FP1 HGNC:HGNC:44535 +100421437 LOC100421437 - +100421438 LOC100421438 - +100421439 TPT1P3 HGNC:HGNC:49295 +100421444 LOC100421444 - +100421446 LOC100421446 - +100421451 HNRNPA3P16 HGNC:HGNC:48762 +100421455 EIF4EP4 HGNC:HGNC:51462 +100421462 LOC100421462 - +100421465 LOC100421465 - +100421468 LOC100421468 - +100421471 LOC100421471 - +100421472 LOC100421472 - +100421473 TVP23BP2 HGNC:HGNC:38869 +100421474 LOC100421474 - +100421478 FAM71BP1 HGNC:HGNC:49805 +100421479 HTR1DP1 HGNC:HGNC:5290 +100421480 TPT1P12 HGNC:HGNC:49303 +100421482 LOC100421482 - +100421483 LOC100421483 - +100421484 MARK2P11 HGNC:HGNC:39802 +100421485 MARK2P5 HGNC:HGNC:39796 +100421487 FAM58CP HGNC:HGNC:38436 +100421490 LOC100421490 - +100421493 LOC100421493 - +100421494 LOC100421494 - +100421495 ACTR6P1 HGNC:HGNC:44210 +100421496 MARK2P4 HGNC:HGNC:39795 +100421498 MARK2P8 HGNC:HGNC:39799 +100421499 MARK2P17 HGNC:HGNC:50318 +100421500 MARK2P6 HGNC:HGNC:39797 +100421501 MARK2P1 HGNC:HGNC:39792 +100421502 MARK2P2 HGNC:HGNC:39793 +100421503 MARK3P2 HGNC:HGNC:50313 +100421504 LOC100421504 - +100421505 LOC100421505 - +100421506 ILF2P1 HGNC:HGNC:44695 +100421507 MARK2P3 HGNC:HGNC:39794 +100421508 LOC100421508 - +100421509 LARP7P4 HGNC:HGNC:49766 +100421510 LOC100421510 - +100421511 LOC100421511 - +100421512 RBPMS2P1 HGNC:HGNC:50509 +100421513 LOC100421513 - +100421515 BMPR1APS1 HGNC:HGNC:21742 +100421517 LOC100421517 - +100421518 LOC100421518 - +100421523 LOC100421523 - +100421525 LOC100421525 - +100421527 LOC100421527 - +100421528 EIF4BP5 HGNC:HGNC:37938 +100421531 MARK2P7 HGNC:HGNC:39798 +100421533 EIF4A1P10 HGNC:HGNC:37930 +100421535 GEMIN8P3 HGNC:HGNC:37978 +100421536 LOC100421536 - +100421537 LOC100421537 - +100421539 SUZ12P2 HGNC:HGNC:43872 +100421541 LOC100421541 - +100421542 DNAJA1P6 HGNC:HGNC:39342 +100421545 EIF4HP2 HGNC:HGNC:49036 +100421548 LOC100421548 - +100421549 RFC5P1 HGNC:HGNC:50450 +100421550 MARK3P1 HGNC:HGNC:50312 +100421558 LOC100421558 - +100421559 LOC100421559 - +100421560 GCNT1P2 HGNC:HGNC:37972 +100421561 LOC100421561 - +100421565 MARK2P12 HGNC:HGNC:39803 +100421566 FAM58DP HGNC:HGNC:42022 +100421569 LOC100421569 - +100421572 MESTP2 HGNC:HGNC:18208 +100421574 LOC100421574 - +100421577 FAM21EP HGNC:HGNC:45010|Ensembl:ENSG00000235618 +100421579 EIF4A2P2 HGNC:HGNC:45099 +100421580 LOC100421580 - +100421581 GCNT1P3 HGNC:HGNC:37973 +100421582 PAIP1P1 HGNC:HGNC:18240 +100421583 LOC100421583 - +100421588 FAM60BP HGNC:HGNC:19052 +100421589 LRRC37A7P HGNC:HGNC:43792 +100421591 LOC100421591 - +100421594 LOC100421594 - +100421595 LOC100421595 - +100421597 LOC100421597 - +100421598 GCNT1P5 HGNC:HGNC:37975 +100421599 TVP23CP1 HGNC:HGNC:44646 +100421601 PPATP2 HGNC:HGNC:48738 +100421602 LOC100421602 - +100421603 LOC100421603 - +100421606 LOC100421606 - +100421610 C4BPAP3 HGNC:HGNC:51640 +100421611 LOC100421611 - +100421614 LOC100421614 - +100421617 LOC100421617 - +100421618 LOC100421618 - +100421620 LOC100421620 - +100421621 FAM187B2P HGNC:HGNC:49213 +100421622 LOC100421622 - +100421623 LOC100421623 - +100421629 METTL21AP1 HGNC:HGNC:41921 +100421630 LOC100421630 - +100421632 LOC100421632 - +100421633 WARS2P1 HGNC:HGNC:45116 +100421634 CUBNP3 HGNC:HGNC:44985 +100421636 LOC100421636 - +100421637 LOC100421637 - +100421638 CTAGE13P HGNC:HGNC:37298 +100421641 LOC100421641 - +100421642 LOC100421642 - +100421646 LOC100421646 - +100421648 SUCLA2P3 HGNC:HGNC:38103 +100421651 LOC100421651 - +100421652 PTP4A1P1 HGNC:HGNC:41928 +100421655 LOC100421655 - +100421657 HNRNPDLP4 HGNC:HGNC:48808 +100421658 LOC100421658 - +100421663 LOC100421663 - +100421664 LOC100421664 - +100421667 LOC100421667 - +100421669 LOC100421669 - +100421670 LOC100421670 - +100421671 SUCLG2P1 HGNC:HGNC:43996 +100421672 LOC100421672 - +100421673 LOC100421673 - +100421674 LOC100421674 - +100421675 ARL2BPP9 HGNC:HGNC:39453 +100421681 PTP4A1P7 HGNC:HGNC:41934 +100421684 LOC100421684 - +100421685 LOC100421685 - +100421689 LOC100421689 - +100421690 LOC100421690 - +100421691 LOC100421691 - +100421692 LOC100421692 - +100421693 LOC100421693 - +100421694 GLULP5 HGNC:HGNC:37989 +100421695 BNIP3P10 HGNC:HGNC:49690 +100421696 BNIP3P14 HGNC:HGNC:49694 +100421697 BNIP3P23 HGNC:HGNC:49703 +100421698 BNIP3P24 HGNC:HGNC:49704 +100421699 BNIP3P26 HGNC:HGNC:49706 +100421700 BNIP3P29 HGNC:HGNC:49709 +100421701 BNIP3P39 HGNC:HGNC:49719 +100421702 BNIP3P40 HGNC:HGNC:49720 +100421703 BNIP3P12 HGNC:HGNC:49692 +100421704 BNIP3P17 HGNC:HGNC:49697 +100421705 BNIP3P20 HGNC:HGNC:49700 +100421706 BNIP3P22 HGNC:HGNC:49702 +100421707 BNIP3P25 HGNC:HGNC:49705 +100421708 BNIP3P27 HGNC:HGNC:49707 +100421709 BNIP3P38 HGNC:HGNC:49718 +100421710 BNIP3P8 HGNC:HGNC:49675 +100421712 SUCLG2P3 HGNC:HGNC:43998 +100421716 UBE2Q2P4Y HGNC:HGNC:38429 +100421717 UBE2Q2P5Y HGNC:HGNC:38466 +100421718 NEK4P1 HGNC:HGNC:39649 +100421721 LOC100421721 - +100421724 BNIP3P5 HGNC:HGNC:39658 +100421728 NEK4P3 HGNC:HGNC:39651 +100421729 VPS26BP1 HGNC:HGNC:44612 +100421730 LOC100421730 - +100421731 VPS26AP1 HGNC:HGNC:44611 +100421733 EEF1GP6 HGNC:HGNC:44561 +100421734 NEK4P2 HGNC:HGNC:39650 +100421736 BNIP3P3 HGNC:HGNC:39656 +100421737 LOC100421737 - +100421741 ARAFP1 HGNC:HGNC:50824 +100421742 LOC100421742 - +100421746 LOC100421746 Ensembl:ENSG00000232765 +100421749 LOC100421749 - +100421751 LOC100421751 - +100421754 BNIP3P2 HGNC:HGNC:39655 +100421756 EEF1B2P7 HGNC:HGNC:51454 +100421765 LOC100421765 - +100421766 UBE2Q2P7 HGNC:HGNC:49413 +100421767 UBE2Q2P11 HGNC:HGNC:49522 +100421768 UBE2Q2P12 HGNC:HGNC:49523 +100421769 UBE2Q2P6 HGNC:HGNC:49412 +100421771 UBE2Q2P8 HGNC:HGNC:49521 +100421774 EEF1B2P8 HGNC:HGNC:51455 +100421775 LOC100421775 - +100421776 NIPA2P4 HGNC:HGNC:42044 +100421779 ACSM5P1 HGNC:HGNC:51295 +100421782 LOC100421782 - +100421784 STK24P1 HGNC:HGNC:50360 +100421787 LOC100421787 - +100421788 LOC100421788 - +100421790 PUS7P1 HGNC:HGNC:49779 +100421793 LOC100421793 - +100421794 HNRNPCP6 HGNC:HGNC:48817 +100421795 ST3GAL5P1 HGNC:HGNC:45175 +100421796 EEF1A1P19 HGNC:HGNC:37892 +100421797 EEF1A1P20 HGNC:HGNC:37893 +100421798 LOC100421798 - +100421799 LONRF2P2 HGNC:HGNC:39829 +100421802 LOC100421802 - +100421803 ENPP7P9 HGNC:HGNC:48692 +100421804 ST3GAL1P1 HGNC:HGNC:45174 +100421805 ENPP7P10 HGNC:HGNC:48693 +100421806 ENPP7P11 HGNC:HGNC:48694 +100421807 EEF1A1P21 HGNC:HGNC:37894 +100421808 LOC100421808 - +100421809 LOC100421809 - +100421810 LOC100421810 - +100421811 LOC100421811 - +100421813 ENPP7P2 HGNC:HGNC:48685 +100421815 EEF1A1P23 HGNC:HGNC:37896 +100421816 ENPP7P4 HGNC:HGNC:48687 +100421817 LOC100421817 - +100421819 LOC100421819 - +100421820 EEF1A1P36 HGNC:HGNC:37914 +100421821 LOC100421821 - +100421822 LOC100421822 - +100421823 ENPP7P1 HGNC:HGNC:48699 +100421824 LOC100421824 - +100421825 EEF1A1P37 HGNC:HGNC:37915 +100421827 LONRF2P1 HGNC:HGNC:39828 +100421828 HNRNPCP4 HGNC:HGNC:48816 +100421829 EEF1A1P10 HGNC:HGNC:3205 +100421840 LOC100421840 - +100421842 LOC100421842 - +100421854 EEF1A1P4 HGNC:HGNC:3199 +100421855 LOC100421855 - +100421859 ENPP7P7 HGNC:HGNC:48690 +100421860 ENPP7P8 HGNC:HGNC:48691 +100421861 CBX3P3 HGNC:HGNC:42875 +100421863 LOC100421863 - +100421865 EEF1A1P3 HGNC:HGNC:3194 +100421868 LOC100421868 - +100421870 LOC100421870 - +100421893 LOC100421893 - +100421894 LOC100421894 - +100421901 LOC100421901 - +100421910 LOC100421910 - +100421925 LOC100421925 - +100421926 NACAP4 HGNC:HGNC:49491 +100421943 CBX3P5 HGNC:HGNC:42877 +100421973 ARPC3P4 HGNC:HGNC:39434 +100421975 CBX3P7 HGNC:HGNC:42879 +100421976 LOC100421976 - +100421985 LOC100421985 - +100422013 LOC100422013 - +100422019 EFTUD1P2 HGNC:HGNC:44202 +100422020 LOC100422020 - +100422021 LOC100422021 - +100422022 LOC100422022 - +100422023 UGT2A3P7 HGNC:HGNC:39429 +100422024 LOC100422024 - +100422026 LOC100422026 - +100422029 LOC100422029 - +100422032 LOC100422032 - +100422044 LOC100422044 - +100422053 LOC100422053 - +100422055 VPS35P1 HGNC:HGNC:51805 +100422059 ABCF2P2 HGNC:HGNC:48842 +100422076 LOC100422076 - +100422088 ASH2LP2 HGNC:HGNC:53059 +100422091 LOC100422091 - +100422094 LOC100422094 - +100422106 LOC100422106 - +100422179 KCTD9P5 HGNC:HGNC:49914 +100422188 LOC100422188 - +100422189 LOC100422189 - +100422190 LOC100422190 - +100422194 LOC100422194 - +100422200 EIF3EP4 HGNC:HGNC:37921 +100422204 LOC100422204 - +100422209 LOC100422209 - +100422212 LOC100422212 - +100422213 LOC100422213 - +100422225 LOC100422225 - +100422227 LOC100422227 - +100422229 MAPRE1P3 HGNC:HGNC:37762 +100422230 KCTD10P1 HGNC:HGNC:49807 +100422232 LOC100422232 - +100422233 LOC100422233 - +100422235 CYP4F36P HGNC:HGNC:42407 +100422238 CYP4F23P HGNC:HGNC:39944 +100422241 LOC100422241 - +100422242 KCTD9P4 HGNC:HGNC:49913 +100422243 NPM1P27 HGNC:HGNC:45206 +100422247 CYP4F34P HGNC:HGNC:39953 +100422249 NPM1P41 HGNC:HGNC:45220 +100422250 SUMO2P11 HGNC:HGNC:49349 +100422254 EBAG9P1 HGNC:HGNC:45233 +100422256 NPM1P23 HGNC:HGNC:44513 +100422259 NPM1P29 HGNC:HGNC:45208 +100422261 NPM1P37 HGNC:HGNC:45216 +100422263 LOC100422263 - +100422264 CYP51A1P3 HGNC:HGNC:41991 +100422265 SUMO2P19 HGNC:HGNC:49357 +100422267 LOC100422267 - +100422268 BRIX1P1 HGNC:HGNC:51527 +100422270 NPM1P44 HGNC:HGNC:45223 +100422271 LOC100422271 - +100422272 NPM1P52 HGNC:HGNC:45231 +100422273 KCTD9P1 HGNC:HGNC:21428 +100422274 LOC100422274 - +100422275 LOC100422275 - +100422284 NPM1P49 HGNC:HGNC:45228 +100422285 LOC100422285 - +100422286 LOC100422286 - +100422287 LOC100422287 - +100422288 CYP4A27P HGNC:HGNC:42414 +100422289 PSMB7P1 HGNC:HGNC:49192 +100422292 LOC100422292 - +100422294 LOC100422294 - +100422296 LOC100422296 - +100422298 LOC100422298 - +100422299 C1QBPP2 HGNC:HGNC:51618 +100422300 LOC100422300 - +100422305 PSMC1P13 HGNC:HGNC:39788 +100422309 NPM1P43 HGNC:HGNC:45222 +100422310 C1QBPP3 HGNC:HGNC:51619 +100422312 NPM1P24 HGNC:HGNC:45097 +100422313 NPM1P26 HGNC:HGNC:45205 +100422315 LOC100422315 - +100422316 NPM1P45 HGNC:HGNC:45224 +100422317 LOC100422317 - +100422319 LOC100422319 - +100422324 LOC100422324 - +100422325 LOC100422325 - +100422330 QRSL1P2 HGNC:HGNC:43668 +100422334 LOC100422334 - +100422337 LOC100422337 - +100422338 LOC100422338 - +100422339 SDR42E1P5 HGNC:HGNC:51832 +100422340 SDR42E1P1 HGNC:HGNC:50378 +100422342 PIGUP1 HGNC:HGNC:45158 +100422343 UPF3AP3 HGNC:HGNC:38395 +100422346 SDR42E1P2 HGNC:HGNC:51833 +100422347 SDR42E1P3 HGNC:HGNC:51834 +100422348 SDR42E1P4 HGNC:HGNC:51835 +100422349 PIGFP2 HGNC:HGNC:45150 +100422352 LOC100422352 - +100422354 CHCHD3P2 HGNC:HGNC:44698 +100422363 BUB1P1 HGNC:HGNC:49529 +100422368 LOC100422368 - +100422369 LOC100422369 - +100422371 RIMKLBP2 HGNC:HGNC:39163 +100422372 NDE1P1 HGNC:HGNC:49115 +100422374 QRSL1P3 HGNC:HGNC:43669 +100422375 LOC100422375 - +100422376 LOC100422376 - +100422381 PPP1R10P1 HGNC:HGNC:16325 +100422382 LOC100422382 - +100422384 POLR3DP1 HGNC:HGNC:45107 +100422385 DIMT1P1 HGNC:HGNC:52892 +100422386 ADAD1P1 HGNC:HGNC:44550 +100422391 POLR3GP2 HGNC:HGNC:50691 +100422395 POLR3GP1 HGNC:HGNC:23345 +100422398 LOC100422398 - +100422399 LOC100422399 - +100422402 LOC100422402 - +100422407 ADAD1P2 HGNC:HGNC:44552 +100422408 LOC100422408 - +100422411 PSMD8P1 HGNC:HGNC:34013 +100422413 LOC100422413 - +100422414 LOC100422414 - +100422416 LOC100422416 - +100422417 LOC100422417 - +100422418 LOC100422418 - +100422426 LOC100422426 - +100422429 NAPGP2 HGNC:HGNC:45166 +100422431 NDUFB5P2 HGNC:HGNC:52268 +100422432 LOC100422432 - +100422434 LOC100422434 - +100422437 MYL6BP1 HGNC:HGNC:51647 +100422438 LOC100422438 - +100422440 LOC100422440 - +100422441 LOC100422441 - +100422445 NUDT19P5 HGNC:HGNC:43589 +100422449 LOC100422449 - +100422450 NUDT19P3 HGNC:HGNC:43587 +100422452 NUDT19P4 HGNC:HGNC:43588 +100422453 LOC100422453 - +100422456 LOC100422456 - +100422458 NUDT19P2 HGNC:HGNC:43586 +100422463 LOC100422463 - +100422467 NUDT21P1 HGNC:HGNC:39461 +100422469 B3GNT2P1 HGNC:HGNC:51316 +100422471 LOC100422471 - +100422473 LOC100422473 - +100422478 LOC100422478 - +100422479 LOC100422479 - +100422486 KRR1P1 HGNC:HGNC:39580 +100422490 LOC100422490 - +100422491 LOC100422491 - +100422492 LOC100422492 - +100422493 LOC100422493 - +100422495 LOC100422495 - +100422496 PRPF19P1 HGNC:HGNC:23182 +100422497 LOC100422497 - +100422500 LOC100422500 - +100422501 LOC100422501 - +100422502 LOC100422502 - +100422505 ATP8A2P1 HGNC:HGNC:39662 +100422510 LOC100422510 - +100422513 LOC100422513 - +100422514 ATP5F1P4 HGNC:HGNC:39745 +100422517 BSNDP2 HGNC:HGNC:51537 +100422519 LOC100422519 - +100422523 ATP5F1P1 HGNC:HGNC:39742 +100422524 LOC100422524 - +100422526 LOC100422526 - +100422527 SLC4A1APP2 HGNC:HGNC:49812 +100422528 LOC100422528 - +100422529 LOC100422529 - +100422530 LOC100422530 - +100422531 FCF1P8 HGNC:HGNC:44620 +100422532 NDUFAF4P3 HGNC:HGNC:44542 +100422533 FCF1P1 HGNC:HGNC:44613 +100422535 FCF1P6 HGNC:HGNC:44618 +100422536 FCF1P7 HGNC:HGNC:44619 +100422537 LOC100422537 - +100422538 LOC100422538 - +100422540 VTI1BP4 HGNC:HGNC:43730 +100422545 HIRAP1 HGNC:HGNC:44916 +100422546 XRCC6P4 HGNC:HGNC:45186 +100422547 SLC16A1P1 HGNC:HGNC:48931 +100422548 LOC100422548 - +100422549 LOC100422549 - +100422550 SLC5A4P1 HGNC:HGNC:45041 +100422556 LOC100422556 - +100422558 SMG1P6 HGNC:HGNC:49863|Ensembl:ENSG00000254634 +100422559 LOC100422559 - +100422561 LOC100422561 - +100422562 LOC100422562 - +100422564 LOC100422564 - +100422580 LOC100422580 - +100422581 DFFBP1 HGNC:HGNC:49815 +100422582 ELOCP31 HGNC:HGNC:49172 +100422587 LOC100422587 - +100422588 MGAT2P1 HGNC:HGNC:51244 +100422589 MGAT2P2 HGNC:HGNC:51243 +100422591 SDHCP3 HGNC:HGNC:45178 +100422593 LOC100422593 - +100422595 PCMTD1P3 HGNC:HGNC:38806 +100422598 SDHCP4 HGNC:HGNC:45179 +100422600 SDHCP1 HGNC:HGNC:31734 +100422602 ST13P14 HGNC:HGNC:38849 +100422603 ST13P15 HGNC:HGNC:38850 +100422604 LOC100422604 - +100422605 ST13P16 HGNC:HGNC:38851 +100422606 SLC25A3P3 HGNC:HGNC:43785 +100422608 SLC25A24P2 HGNC:HGNC:48934 +100422610 LOC100422610 - +100422614 LOC100422614 - +100422622 LOC100422622 - +100422623 LOC100422623 - +100422624 SLC25A15P1 HGNC:HGNC:18497 +100422625 GOT2P5 HGNC:HGNC:38439 +100422627 LOC100422627 - +100422628 LOC100422628 - +100422633 LOC100422633 - +100422634 CASP1P3 HGNC:HGNC:43777 +100422635 SLC25A15P3 HGNC:HGNC:39844 +100422636 SLC25A15P4 HGNC:HGNC:39845 +100422637 LOC100422637 - +100422638 LOC100422638 - +100422639 LOC100422639 - +100422640 LOC100422640 - +100422641 LOC100422641 - +100422642 SLC25A15P5 HGNC:HGNC:39846 +100422644 SERPINA7P1 HGNC:HGNC:44398 +100422645 LOC100422645 - +100422646 LOC100422646 - +100422656 EEF1DP7 HGNC:HGNC:51457 +100422657 RAC1P6 HGNC:HGNC:42006 +100422658 RAC1P9 HGNC:HGNC:50774 +100422666 YWHABP2 HGNC:HGNC:50295 +100422669 LOC100422669 - +100422671 LOC100422671 - +100422674 YWHAQP7 HGNC:HGNC:37686 +100422685 LOC100422685 - +100422686 SLC25A6P3 HGNC:HGNC:43852 +100422687 LOC100422687 - +100422690 SLC25A6P4 HGNC:HGNC:43853 +100422691 ITGB1P1 HGNC:HGNC:3781 +100422693 LOC100422693 - +100422694 LOC100422694 - +100422695 LOC100422695 - +100422696 LOC100422696 - +100422710 LOC100422710 - +100422711 THAP12P2 HGNC:HGNC:39566 +100422712 THAP12P7 HGNC:HGNC:39574 +100422713 LOC100422713 - +100422715 THAP12P10 HGNC:HGNC:39741 +100422716 ST6GALNAC2P1 HGNC:HGNC:45160 +100422717 LOC100422717 - +100422730 LOC100422730 - +100422737 LINC02532 HGNC:HGNC:53549|Ensembl:ENSG00000235142 +100422781 LOC100422781 - +100422821 MIR1273C HGNC:HGNC:38173|Ensembl:ENSG00000264814|miRBase:MI0014171 +100422823 MIR4300 HGNC:HGNC:38184|Ensembl:ENSG00000264110|miRBase:MI0015831 +100422824 MIR3128 HGNC:HGNC:38188|Ensembl:ENSG00000265396|miRBase:MI0014145 +100422825 MIR3160-2 HGNC:HGNC:38192|Ensembl:ENSG00000283497|miRBase:MI0014190 +100422826 MIR4274 HGNC:HGNC:38194|Ensembl:ENSG00000266690|miRBase:MI0015884 +100422827 MIR3160-1 HGNC:HGNC:38197|Ensembl:ENSG00000265014|miRBase:MI0014189 +100422828 MIR4287 HGNC:HGNC:38208|Ensembl:ENSG00000265847|miRBase:MI0015895 +100422829 MIR4319 HGNC:HGNC:38212|Ensembl:ENSG00000265957|miRBase:MI0015848 +100422830 MIR3171 HGNC:HGNC:38216|Ensembl:ENSG00000264657|miRBase:MI0014202 +100422831 MIR1302-9 HGNC:HGNC:38218|Ensembl:ENSG00000283921|miRBase:MI0015978 +100422832 MIR3191 HGNC:HGNC:38222|Ensembl:ENSG00000284411|miRBase:MI0014236 +100422833 MIR3188 HGNC:HGNC:38226|Ensembl:ENSG00000267959|miRBase:MI0014232 +100422834 MIR1302-10 HGNC:HGNC:38233|Ensembl:ENSG00000284557|miRBase:MI0015979 +100422835 MIR3183 HGNC:HGNC:38237|Ensembl:ENSG00000264429|miRBase:MI0014225 +100422836 MIR3180-3 HGNC:HGNC:38239|Ensembl:ENSG00000266291|miRBase:MI0014217 +100422837 MIR1193 HGNC:HGNC:38247|Ensembl:ENSG00000221036|miRBase:MI0014205 +100422838 MIR3195 HGNC:HGNC:38250|Ensembl:ENSG00000265306|miRBase:MI0014240 +100422839 MIR3119-1 HGNC:HGNC:38253|Ensembl:ENSG00000283340|miRBase:MI0014134 +100422840 MIR4317 HGNC:HGNC:38260|Ensembl:ENSG00000283532|miRBase:MI0015850 +100422841 MIR3174 HGNC:HGNC:38264|Ensembl:ENSG00000265871|miRBase:MI0014208 +100422842 MIR3074 HGNC:HGNC:38268|Ensembl:ENSG00000207617|miRBase:MI0014181 +100422843 MIR4293 HGNC:HGNC:38270|Ensembl:ENSG00000266321|miRBase:MI0015826 +100422844 MIR3118-3 HGNC:HGNC:38274|Ensembl:ENSG00000277243|miRBase:MI0014133 +100422845 MIR1233-2 HGNC:HGNC:38277|Ensembl:ENSG00000221065|miRBase:MI0015973 +100422846 MIR3164 HGNC:HGNC:38288|Ensembl:ENSG00000265539|miRBase:MI0014194 +100422847 MIR514B HGNC:HGNC:38292|Ensembl:ENSG00000252583|miRBase:MI0014251 +100422848 MIR4283-2 HGNC:HGNC:38296|Ensembl:ENSG00000265214|miRBase:MI0015982 +100422849 MIR548T HGNC:HGNC:38298|Ensembl:ENSG00000221296|miRBase:MI0014164 +100422850 MIR548V HGNC:HGNC:38302|Ensembl:ENSG00000265520|miRBase:MI0014174 +100422851 MIR4316 HGNC:HGNC:38306|Ensembl:ENSG00000264060|miRBase:MI0015845 +100422852 MIR4259 HGNC:HGNC:38309|Ensembl:ENSG00000266458|miRBase:MI0015858 +100422853 MIR3182 HGNC:HGNC:38317|Ensembl:ENSG00000263785|miRBase:MI0014224 +100422854 MIR3187 HGNC:HGNC:38319|Ensembl:ENSG00000263414|miRBase:MI0014231 +100422855 MIR4301 HGNC:HGNC:38323|Ensembl:ENSG00000265140|miRBase:MI0015828 +100422856 MIR3123 HGNC:HGNC:38330|Ensembl:ENSG00000265831|miRBase:MI0014139 +100422857 MIR4318 HGNC:HGNC:38333|Ensembl:ENSG00000266530|miRBase:MI0015847 +100422858 MIR4285 HGNC:HGNC:38337|Ensembl:ENSG00000264675|miRBase:MI0015891 +100422859 MIR3136 HGNC:HGNC:38340|Ensembl:ENSG00000265355|miRBase:MI0014158 +100422860 MIR4292 HGNC:HGNC:38348|Ensembl:ENSG00000265806|miRBase:MI0015897 +100422861 MIR4306 HGNC:HGNC:38350|Ensembl:ENSG00000263615|miRBase:MI0015836 +100422862 MIR548S HGNC:HGNC:38354|Ensembl:ENSG00000265056|miRBase:MI0014141 +100422863 MIR4265 HGNC:HGNC:38358|Ensembl:ENSG00000264934|miRBase:MI0015869 +100422864 MIR544B HGNC:HGNC:38361|Ensembl:ENSG00000265981|miRBase:MI0014159 +100422865 MIR4320 HGNC:HGNC:38369|Ensembl:ENSG00000283343|miRBase:MI0015849 +100422866 MIR3115 HGNC:HGNC:38371|Ensembl:ENSG00000263793|miRBase:MI0014127 +100422867 MIR378C HGNC:HGNC:38374|Ensembl:ENSG00000264803|miRBase:MI0015825 +100422868 MIR4270 HGNC:HGNC:38377|Ensembl:ENSG00000263573|miRBase:MI0015878 +100422869 MIR3152 HGNC:HGNC:38379|Ensembl:ENSG00000264638|miRBase:MI0014179 +100422870 MIR3180-1 HGNC:HGNC:38382|Ensembl:ENSG00000265537|miRBase:MI0014214 +100422871 MIR3117 HGNC:HGNC:38385|Ensembl:ENSG00000264720|miRBase:MI0014130 +100422872 MIR1244-3 HGNC:HGNC:38390|Ensembl:ENSG00000283429|miRBase:MI0015975 +100422873 MIR4297 HGNC:HGNC:38393|Ensembl:ENSG00000266676|miRBase:MI0015824 +100422874 MIR4279 HGNC:HGNC:38195|Ensembl:ENSG00000266243|miRBase:MI0015887 +100422875 MIR3192 HGNC:HGNC:38202|Ensembl:ENSG00000265137|miRBase:MI0014237 +100422876 MIR3148 HGNC:HGNC:38215|Ensembl:ENSG00000264788|miRBase:MI0014175 +100422877 MIR3202-2 HGNC:HGNC:38228|Ensembl:ENSG00000283694|miRBase:MI0014253 +100422878 MIR3168 HGNC:HGNC:38249|Ensembl:ENSG00000264226|miRBase:MI0014199 +100422879 MIR3124 HGNC:HGNC:38262|Ensembl:ENSG00000264500|miRBase:MI0014140 +100422880 MIR3162 HGNC:HGNC:38271|Ensembl:ENSG00000264559|miRBase:MI0014192 +100422881 MIR3170 HGNC:HGNC:38282|Ensembl:ENSG00000263399|miRBase:MI0014201 +100422882 MIR3120 MIM:614722|HGNC:HGNC:38295|Ensembl:ENSG00000283152|miRBase:MI0014136 +100422883 MIR4325 HGNC:HGNC:38304|Ensembl:ENSG00000266666|miRBase:MI0015865 +100422884 MIR548U HGNC:HGNC:38316|Ensembl:ENSG00000212017|miRBase:MI0014168 +100422885 MIR1244-2 HGNC:HGNC:38321|Ensembl:ENSG00000283498|miRBase:MI0015974 +100422886 MIR3179-2 HGNC:HGNC:38325|Ensembl:ENSG00000257381|miRBase:MI0014216 +100422887 MIR4280 HGNC:HGNC:38334|Ensembl:ENSG00000265919|miRBase:MI0015889 +100422888 MIR4264 HGNC:HGNC:38338|Ensembl:ENSG00000266436|miRBase:MI0015877 +100422889 MIR3194 HGNC:HGNC:38346|Ensembl:ENSG00000266761|miRBase:MI0014239 +100422891 MIR4327 HGNC:HGNC:38355|Ensembl:ENSG00000265007|miRBase:MI0015867 +100422892 MIR3157 HGNC:HGNC:38172|Ensembl:ENSG00000266407|miRBase:MI0014185 +100422893 MIR3154 HGNC:HGNC:38176|Ensembl:ENSG00000264823|miRBase:MI0014182 +100422894 MIR4260 HGNC:HGNC:38179|Ensembl:ENSG00000283876|miRBase:MI0015859 +100422895 MIR4294 HGNC:HGNC:38180|Ensembl:ENSG00000264800|miRBase:MI0015827 +100422896 MIR3140 HGNC:HGNC:38183|Ensembl:ENSG00000264678|miRBase:MI0014163 +100422897 MIR4302 HGNC:HGNC:38185|Ensembl:ENSG00000283603|miRBase:MI0015833 +100422898 MIR4255 HGNC:HGNC:38187|Ensembl:ENSG00000264698|miRBase:MI0015863 +100422899 MIR3190 HGNC:HGNC:38190|Ensembl:ENSG00000265134|miRBase:MI0014235 +100422900 MIR3158-1 HGNC:HGNC:38196|Ensembl:ENSG00000263436|miRBase:MI0014186 +100422901 MIR3135A HGNC:HGNC:38199|Ensembl:ENSG00000266745|miRBase:MI0014156 +100422902 MIR3116-1 HGNC:HGNC:38200|Ensembl:ENSG00000263908|miRBase:MI0014128 +100422903 MIR4288 HGNC:HGNC:38203|Ensembl:ENSG00000265251|miRBase:MI0015896 +100422904 MIR3193 HGNC:HGNC:38204|Ensembl:ENSG00000264395|miRBase:MI0014238 +100422905 MIR4311 HGNC:HGNC:38207|Ensembl:ENSG00000263512|miRBase:MI0015841 +100422907 MIR3156-2 HGNC:HGNC:38213|Ensembl:ENSG00000265499|miRBase:MI0014230 +100422908 MIR3129 HGNC:HGNC:38217|Ensembl:ENSG00000264725|miRBase:MI0014146 +100422909 MIR4295 HGNC:HGNC:38220|Ensembl:ENSG00000264763|miRBase:MI0015822 +100422910 MIR2861 MIM:613405|HGNC:HGNC:38221|Ensembl:ENSG00000284547|miRBase:MI0013006 +100422911 MIR500B HGNC:HGNC:38223|Ensembl:ENSG00000239057|miRBase:MI0015903 +100422912 MIR3200 HGNC:HGNC:38227|Ensembl:ENSG00000264661|miRBase:MI0014249 +100422913 MIR320E HGNC:HGNC:38230|Ensembl:ENSG00000211513|miRBase:MI0014234 +100422914 MIR4253 HGNC:HGNC:38231|Ensembl:ENSG00000264014|miRBase:MI0015860 +100422915 MIR3065 HGNC:HGNC:38234|Ensembl:ENSG00000211563|miRBase:MI0014228 +100422916 MIR3201 HGNC:HGNC:38235|Ensembl:ENSG00000266508|miRBase:MI0014250 +100422917 MIR4283-1 HGNC:HGNC:38238|Ensembl:ENSG00000264426|miRBase:MI0015892 +100422918 MIR3167 HGNC:HGNC:38242|Ensembl:ENSG00000266215|miRBase:MI0014198 +100422919 MIR1302-11 HGNC:HGNC:38246|Ensembl:ENSG00000283801|miRBase:MI0015980 +100422920 MIR548X HGNC:HGNC:38248|Ensembl:ENSG00000265841|miRBase:MI0014244 +100422921 MIR3149 HGNC:HGNC:38251|Ensembl:ENSG00000266712|miRBase:MI0014176 +100422922 MIR1972-2 HGNC:HGNC:38252|Ensembl:ENSG00000239118|miRBase:MI0015977 +100422923 MIR548W HGNC:HGNC:38255|Ensembl:ENSG00000265005|miRBase:MI0014222 +100422924 MIR4303 HGNC:HGNC:38256|Ensembl:ENSG00000263890|miRBase:MI0015834 +100422925 MIR4322 HGNC:HGNC:38261|Ensembl:ENSG00000264266|miRBase:MI0015851 +100422926 MIR3137 HGNC:HGNC:38263|Ensembl:ENSG00000265333|miRBase:MI0014160 +100422927 MIR4291 HGNC:HGNC:38267|Ensembl:ENSG00000265347|miRBase:MI0015900 +100422928 MIR3127 HGNC:HGNC:38269|Ensembl:ENSG00000264157|miRBase:MI0014144 +100422929 MIR4261 HGNC:HGNC:38272|Ensembl:ENSG00000265418|miRBase:MI0015868 +100422930 MIR4330 HGNC:HGNC:38273|Ensembl:ENSG00000265789|miRBase:MI0015902 +100422931 MIR4304 HGNC:HGNC:38276|Ensembl:ENSG00000265526|miRBase:MI0015832 +100422932 MIR4328 HGNC:HGNC:38280|Ensembl:ENSG00000283622|miRBase:MI0015904 +100422933 MIR378B HGNC:HGNC:38283|Ensembl:ENSG00000264534|miRBase:MI0014154 +100422934 MIR3143 HGNC:HGNC:38284|Ensembl:ENSG00000265565|miRBase:MI0014167 +100422935 MIR3118-4 HGNC:HGNC:38287|Ensembl:ENSG00000265793|miRBase:MI0014207 +100422936 MIR3153 HGNC:HGNC:38289|Ensembl:ENSG00000265112|miRBase:MI0014180 +100422937 MIR4275 HGNC:HGNC:38293|Ensembl:ENSG00000283275|miRBase:MI0015883 +100422938 MIR3142 HGNC:HGNC:38297|miRBase:MI0014166 +100422939 MIR3147 HGNC:HGNC:38300|Ensembl:ENSG00000266168|miRBase:MI0014173 +100422940 MIR4305 HGNC:HGNC:38301|Ensembl:ENSG00000264171|miRBase:MI0015835 +100422941 MIR4272 HGNC:HGNC:38303|Ensembl:ENSG00000283298|miRBase:MI0015880 +100422942 MIR3133 HGNC:HGNC:38305|Ensembl:ENSG00000263752|miRBase:MI0014153 +100422943 MIR3189 HGNC:HGNC:38307|Ensembl:ENSG00000264175|miRBase:MI0014233 +100422944 MIR3186 HGNC:HGNC:38311|Ensembl:ENSG00000266189|miRBase:MI0014229 +100422945 MIR4326 HGNC:HGNC:38314|Ensembl:ENSG00000266104|miRBase:MI0015866 +100422946 MIR3116-2 HGNC:HGNC:38318|Ensembl:ENSG00000283690|miRBase:MI0014129 +100422947 MIR3122 HGNC:HGNC:38320|Ensembl:ENSG00000264358|miRBase:MI0014138 +100422948 MIR4284 HGNC:HGNC:38322|Ensembl:ENSG00000265724|miRBase:MI0015893 +100422949 MIR3118-2 HGNC:HGNC:38324|Ensembl:ENSG00000265322|miRBase:MI0014132 +100422950 MIR3141 HGNC:HGNC:38326|Ensembl:ENSG00000264760|miRBase:MI0014165 +100422951 MIR3144 HGNC:HGNC:38331|Ensembl:ENSG00000265725|miRBase:MI0014169 +100422952 MIR4271 MIM:617176|HGNC:HGNC:38332|Ensembl:ENSG00000264633|miRBase:MI0015879 +100422953 MIR3165 HGNC:HGNC:38335|Ensembl:ENSG00000263742|miRBase:MI0014195 +100422954 MIR4309 HGNC:HGNC:38336|Ensembl:ENSG00000266015|miRBase:MI0015837 +100422955 MIR4273 HGNC:HGNC:38339|Ensembl:ENSG00000266396|miRBase:MI0015881 +100422956 MIR3180-2 HGNC:HGNC:38343|Ensembl:ENSG00000265373|miRBase:MI0014215 +100422957 MIR3131 HGNC:HGNC:38347|Ensembl:ENSG00000264755|miRBase:MI0014151 +100422959 MIR4268 HGNC:HGNC:38352|Ensembl:ENSG00000266518|miRBase:MI0015874 +100422960 MIR3179-1 HGNC:HGNC:38353|Ensembl:ENSG00000284305|miRBase:MI0014213 +100422961 MIR4315-2 HGNC:HGNC:38356|Ensembl:ENSG00000284172|miRBase:MI0015983 +100422962 MIR4281 HGNC:HGNC:38357|Ensembl:ENSG00000266329|miRBase:MI0015885 +100422963 MIR4290 HGNC:HGNC:38360|Ensembl:ENSG00000263967|miRBase:MI0015899 +100422964 MIR3150A HGNC:HGNC:38362|Ensembl:ENSG00000283522|miRBase:MI0014177 +100422965 MIR4263 HGNC:HGNC:38365|Ensembl:ENSG00000265321|miRBase:MI0015876 +100422966 MIR4277 HGNC:HGNC:38367|Ensembl:ENSG00000263746|miRBase:MI0015886 +100422967 MIR3146 HGNC:HGNC:38368|Ensembl:ENSG00000265932|miRBase:MI0014172 +100422968 MIR4251 HGNC:HGNC:38370|Ensembl:ENSG00000283572|miRBase:MI0015861 +100422969 MIR2909 HGNC:HGNC:38372|Ensembl:ENSG00000276326|miRBase:MI0013083 +100422970 MIR1273D HGNC:HGNC:38375|Ensembl:ENSG00000264881|miRBase:MI0014254 +100422971 MIR4312 HGNC:HGNC:38376|Ensembl:ENSG00000265195|miRBase:MI0015842 +100422972 MIR3181 HGNC:HGNC:38378|Ensembl:ENSG00000264947|miRBase:MI0014223 +100422973 MIR3169 HGNC:HGNC:38380|Ensembl:ENSG00000266663|miRBase:MI0014200 +100422974 MIR3178 HGNC:HGNC:38381|Ensembl:ENSG00000266232|miRBase:MI0014212 +100422975 MIR4252 HGNC:HGNC:38384|Ensembl:ENSG00000265392|miRBase:MI0015864 +100422976 MIR4256 HGNC:HGNC:38388|Ensembl:ENSG00000283296|miRBase:MI0015855 +100422977 MIR1184-3 HGNC:HGNC:38389|Ensembl:ENSG00000221603|miRBase:MI0015972 +100422978 MIR3185 HGNC:HGNC:38391|Ensembl:ENSG00000263602|miRBase:MI0014227 +100422979 MIR4324 HGNC:HGNC:38392|Ensembl:ENSG00000265407|miRBase:MI0015854 +100422980 MIR4323 HGNC:HGNC:38394|Ensembl:ENSG00000266226|miRBase:MI0015853 +100422981 MIR3173 HGNC:HGNC:38174|Ensembl:ENSG00000264607|miRBase:MI0014204 +100422982 MIR4286 HGNC:HGNC:38186|Ensembl:ENSG00000263762|miRBase:MI0015894 +100422983 MIR4314 HGNC:HGNC:38191|Ensembl:ENSG00000264005|miRBase:MI0015846 +100422984 MIR4308 HGNC:HGNC:38206|Ensembl:ENSG00000265432|miRBase:MI0015839 +100422985 MIR1184-2 HGNC:HGNC:38211|Ensembl:ENSG00000221190|miRBase:MI0015971 +100422986 MIR3125 HGNC:HGNC:38219|Ensembl:ENSG00000264370|miRBase:MI0014142 +100422987 MIR3202-1 HGNC:HGNC:38224|Ensembl:ENSG00000265176|miRBase:MI0014252 +100422988 MIR3156-1 HGNC:HGNC:38241|Ensembl:ENSG00000263476|miRBase:MI0014184 +100422989 MIR3155A HGNC:HGNC:38245|Ensembl:ENSG00000263628|miRBase:MI0014183 +100422990 MIR3134 HGNC:HGNC:38254|Ensembl:ENSG00000264354|miRBase:MI0014155 +100422991 MIR1260B MIM:615372|HGNC:HGNC:38258|Ensembl:ENSG00000266192|miRBase:MI0014197 +100422992 MIR3151 HGNC:HGNC:38266|Ensembl:ENSG00000265657|miRBase:MI0014178 +100422993 MIR3130-1 HGNC:HGNC:38275|Ensembl:ENSG00000283469|miRBase:MI0014147 +100422994 MIR4267 HGNC:HGNC:38286|Ensembl:ENSG00000265682|miRBase:MI0015871 +100422995 MIR3175 HGNC:HGNC:38299|Ensembl:ENSG00000284324|miRBase:MI0014209 +100422996 MIR4262 HGNC:HGNC:38308|Ensembl:ENSG00000265172|miRBase:MI0015872 +100422997 MIR4257 HGNC:HGNC:38312|Ensembl:ENSG00000264553|miRBase:MI0015856 +100422998 MIR3199-2 HGNC:HGNC:38205|Ensembl:ENSG00000283225|miRBase:MI0014248 +100422999 MIR4278 HGNC:HGNC:38243|Ensembl:ENSG00000283420|miRBase:MI0015888 +100423000 MIR3161 HGNC:HGNC:38285|Ensembl:ENSG00000263693|miRBase:MI0014191 +100423001 MIR3145 HGNC:HGNC:38327|Ensembl:ENSG00000266555|miRBase:MI0014170 +100423002 MIR3130-2 HGNC:HGNC:38363|Ensembl:ENSG00000263468|miRBase:MI0014148 +100423003 MIR3184 HGNC:HGNC:38182|Ensembl:ENSG00000284399|miRBase:MI0014226 +100423004 MIR4315-1 HGNC:HGNC:38342|Ensembl:ENSG00000284055|miRBase:MI0015844 +100423005 MIR4282 HGNC:HGNC:38189|Ensembl:ENSG00000266180|miRBase:MI0015890 +100423006 MIR3179-3 HGNC:HGNC:38214|Ensembl:ENSG00000266454|miRBase:MI0014221 +100423008 MIR3118-1 HGNC:HGNC:38265|Ensembl:ENSG00000266299|miRBase:MI0014131 +100423009 MIR4329 HGNC:HGNC:38290|Ensembl:ENSG00000283775|miRBase:MI0015901 +100423010 MIR3119-2 HGNC:HGNC:38315|Ensembl:ENSG00000263390|miRBase:MI0014135 +100423011 MIR3138 HGNC:HGNC:38341|Ensembl:ENSG00000264931|miRBase:MI0014161 +100423012 MIR3177 HGNC:HGNC:38364|Ensembl:ENSG00000265820|miRBase:MI0014211 +100423013 MIR4310 HGNC:HGNC:38383|Ensembl:ENSG00000264850|miRBase:MI0015840 +100423014 MIR3196 HGNC:HGNC:38198|Ensembl:ENSG00000266463|miRBase:MI0014241 +100423015 MIR4289 HGNC:HGNC:38278|Ensembl:ENSG00000265873|miRBase:MI0015898 +100423016 MIR3159 HGNC:HGNC:38181|Ensembl:ENSG00000264603|miRBase:MI0014188 +100423017 MIR3139 HGNC:HGNC:38201|Ensembl:ENSG00000265623|miRBase:MI0014162 +100423018 MIR3156-3 HGNC:HGNC:38229|Ensembl:ENSG00000266211|miRBase:MI0014242 +100423019 MIR4307 HGNC:HGNC:38257|Ensembl:ENSG00000265165|miRBase:MI0015838 +100423020 MIR4258 HGNC:HGNC:38281|Ensembl:ENSG00000264349|miRBase:MI0015857 +100423021 MIR4298 HGNC:HGNC:38313|Ensembl:ENSG00000264493|miRBase:MI0015830 +100423023 MIR3197 HGNC:HGNC:38366|Ensembl:ENSG00000263681|miRBase:MI0014245 +100423025 MIR3198-1 HGNC:HGNC:38236|Ensembl:ENSG00000264757|miRBase:MI0014246 +100423026 MIR4299 HGNC:HGNC:38329|Ensembl:ENSG00000266645|miRBase:MI0015829 +100423027 MIR4266 HGNC:HGNC:38175|Ensembl:ENSG00000265965|miRBase:MI0015870 +100423028 MIR4254 HGNC:HGNC:38193|Ensembl:ENSG00000266580|miRBase:MI0015862 +100423029 MIR3163 HGNC:HGNC:38209|Ensembl:ENSG00000266423|miRBase:MI0014193 +100423030 MIR3126 HGNC:HGNC:38225|Ensembl:ENSG00000266649|miRBase:MI0014143 +100423031 MIR4321 HGNC:HGNC:38244|Ensembl:ENSG00000284272|miRBase:MI0015852 +100423032 MIR3121 HGNC:HGNC:38259|Ensembl:ENSG00000265435|miRBase:MI0014137 +100423033 MIR3158-2 HGNC:HGNC:38279|Ensembl:ENSG00000283558|miRBase:MI0014187 +100423034 MIR3199-1 HGNC:HGNC:38294|Ensembl:ENSG00000264073|miRBase:MI0014247 +100423035 MIR4313 HGNC:HGNC:38310|Ensembl:ENSG00000284385|miRBase:MI0015843 +100423036 MIR2355 HGNC:HGNC:38328|Ensembl:ENSG00000253008|miRBase:MI0015873 +100423037 MIR3176 HGNC:HGNC:38345|Ensembl:ENSG00000266235|miRBase:MI0014210 +100423038 MIR466 HGNC:HGNC:38359|Ensembl:ENSG00000265376|miRBase:MI0014157 +100423039 MIR3132 HGNC:HGNC:38373|Ensembl:ENSG00000265252|miRBase:MI0014152 +100423040 MIR3166 HGNC:HGNC:38386|Ensembl:ENSG00000266581|miRBase:MI0014196 +100423041 MIR4296 HGNC:HGNC:38178|Ensembl:ENSG00000264572|miRBase:MI0015823 +100423042 MIR4276 MIM:616274|HGNC:HGNC:38232|Ensembl:ENSG00000265846|miRBase:MI0015882 +100423043 MIR4269 HGNC:HGNC:38291|Ensembl:ENSG00000265215|miRBase:MI0015875 +100423044 LOC100423044 - +100423046 STX8P1 HGNC:HGNC:49855 +100423060 ASNSP6 HGNC:HGNC:49876 +100423061 ASNSP3 HGNC:HGNC:39399 +100423062 IGLL5 HGNC:HGNC:38476|Ensembl:ENSG00000254709|Vega:OTTHUMG00000165670 +100431168 MYL6P2 HGNC:HGNC:23772 +100431172 KLRF2 HGNC:HGNC:37646|Ensembl:ENSG00000256797|Vega:OTTHUMG00000187141 +100431173 RNY4P16 HGNC:HGNC:34066 +100431174 LOC100431174 - +100431175 LOC100431175 - +100431177 BHLHB9P1 HGNC:HGNC:51373 +100462647 NKAIN1P1 HGNC:HGNC:38593 +100462648 LOC100462648 - +100462652 LOC100462652 - +100462676 RCHTS MIM:613328 +100462721 INTLQ1 MIM:603783 +100462722 INTLQ3 MIM:610294 +100462723 INTLQ2 MIM:610295 +100462724 OFC9 MIM:610361 +100462725 NAFLD2 MIM:613387 +100462732 ATP6V1G1P6 HGNC:HGNC:37673 +100462767 ACTBP12 HGNC:HGNC:150 +100462772 FTH1P22 HGNC:HGNC:37640 +100462776 RRAGAP1 HGNC:HGNC:20242 +100462780 FTLP9 HGNC:HGNC:37958 +100462782 MEMO1P3 HGNC:HGNC:38503 +100462785 MEMO1P4 HGNC:HGNC:38504 +100462786 FTLP18 HGNC:HGNC:37968 +100462787 CICP10 HGNC:HGNC:37901 +100462788 FTLP6 HGNC:HGNC:37954 +100462790 FTLP8 HGNC:HGNC:37956 +100462792 FTLP12 HGNC:HGNC:37961 +100462793 FTLP13 HGNC:HGNC:37963 +100462794 FTLP14 HGNC:HGNC:37964 +100462795 H2AFZP4 HGNC:HGNC:38015 +100462797 FTH1P24 HGNC:HGNC:37642 +100462799 FTH1P25 HGNC:HGNC:37643 +100462800 H2AFZP6 HGNC:HGNC:38019 +100462809 RSL24D1P8 HGNC:HGNC:37873 +100462810 RHOT1P3 HGNC:HGNC:37839 +100462811 RHOT1P2 HGNC:HGNC:37838 +100462812 FGFR3P1 HGNC:HGNC:21664 +100462813 RHOT1P1 HGNC:HGNC:23777 +100462815 FGFR3P2 HGNC:HGNC:37947 +100462816 FGFR3P3 HGNC:HGNC:37948 +100462820 USP9YP6 HGNC:HGNC:38078 +100462821 USP9YP7 HGNC:HGNC:38079 +100462824 EIF4A1P3 HGNC:HGNC:37922 +100462825 ATP7BP1 HGNC:HGNC:31014 +100462826 EIF4A1P13 HGNC:HGNC:37934 +100462829 GCNT1P4 HGNC:HGNC:37974 +100462830 EIF4A1P12 HGNC:HGNC:37933 +100462832 PNPLA4P1 HGNC:HGNC:38085 +100462833 ISCUP1 HGNC:HGNC:38021 +100462836 EIF3EP3 HGNC:HGNC:37920 +100462838 ATP6V1G1P3 HGNC:HGNC:37670 +100462840 ATP6V1G1P5 HGNC:HGNC:37672 +100462843 ATP6V1G1P4 HGNC:HGNC:37671 +100462844 ATP6V1E1P2 HGNC:HGNC:860 +100462850 COX6B1P4 HGNC:HGNC:2284 +100462851 COX6B1P6 HGNC:HGNC:37676 +100462857 LSM6P2 HGNC:HGNC:37811 +100462862 ATP5LP8 HGNC:HGNC:38170 +100462865 ATP5LP6 HGNC:HGNC:38168 +100462866 ELOCP21 HGNC:HGNC:38157 +100462867 ELOCP6 HGNC:HGNC:38142 +100462868 ELOCP7 HGNC:HGNC:38143 +100462869 ELOCP8 HGNC:HGNC:38144 +100462870 ELOCP9 HGNC:HGNC:38145 +100462871 ELOCP10 HGNC:HGNC:38146 +100462872 ELOCP11 HGNC:HGNC:38147 +100462873 ELOCP4 HGNC:HGNC:38141 +100462874 ELOCP12 HGNC:HGNC:38148 +100462875 ELOCP13 HGNC:HGNC:38149 +100462876 ELOCP14 HGNC:HGNC:38150 +100462877 ELOCP15 HGNC:HGNC:38151 +100462878 ELOCP16 HGNC:HGNC:38152 +100462879 ELOCP17 HGNC:HGNC:38153 +100462880 ELOCP19 HGNC:HGNC:38155 +100462881 ELOCP23 HGNC:HGNC:38159 +100462886 TAF13P2 HGNC:HGNC:38161 +100462953 MINOS1P1 HGNC:HGNC:25036 +100462954 MINOS1P3 HGNC:HGNC:44093 +100462957 MINOS1P4 HGNC:HGNC:44094 +100462977 MTRNR2L1 MIM:616985|HGNC:HGNC:37155|Ensembl:ENSG00000256618|Vega:OTTHUMG00000179068 +100462981 MTRNR2L2 HGNC:HGNC:37156 +100462982 CCT5-2P - +100462983 MTRNR2L3 HGNC:HGNC:37157|Ensembl:ENSG00000256222|Vega:OTTHUMG00000184962 +100462984 HSPD1P22 HGNC:HGNC:39502 +100462985 HSPD1P16 HGNC:HGNC:35128 +100462986 HSPD1P17 HGNC:HGNC:35147 +100462987 HSPD1P13 HGNC:HGNC:35138 +100462988 LOC100462988 - +100462989 HSPD1P20 HGNC:HGNC:38591 +100462990 HSPD1P21 HGNC:HGNC:38592 +100463285 MTRNR2L4 HGNC:HGNC:37161|Ensembl:ENSG00000232196|Vega:OTTHUMG00000184964 +100463286 CCT6P5 HGNC:HGNC:38608 +100463288 HSPD1P19 HGNC:HGNC:38590 +100463289 MTRNR2L5 HGNC:HGNC:37162|Ensembl:ENSG00000249860|Vega:OTTHUMG00000184965 +100463482 MTRNR2L6 HGNC:HGNC:37163|Ensembl:ENSG00000270672|Vega:OTTHUMG00000184977 +100463486 MTRNR2L8 HGNC:HGNC:37165|Ensembl:ENSG00000255823|Vega:OTTHUMG00000184980 +100463487 MTRNR2L9 HGNC:HGNC:37166 +100463488 MTRNR2L10 HGNC:HGNC:37167|Ensembl:ENSG00000256045|Vega:OTTHUMG00000184991 +100463489 MTRNR2L11 HGNC:HGNC:37168 +100463498 MTRNR2L12 HGNC:HGNC:37169|Vega:OTTHUMG00000175726 +100463500 MTRNR2L13 HGNC:HGNC:37170|Vega:OTTHUMG00000184994 +100463528 LSP1P1 HGNC:HGNC:39716 +100498661 OSBPL9P4 HGNC:HGNC:48734 +100498859 LINC00881 HGNC:HGNC:48567|Ensembl:ENSG00000241135 +100499165 FGQTL1 MIM:612108 +100499166 LPRS6 MIM:613407 +100499167 EOE2 MIM:613412 +100499168 FGQTL6 MIM:613460 +100499169 FGQTL4 MIM:613462 +100499171 LINC00276 HGNC:HGNC:38663|Ensembl:ENSG00000230448 +100499177 THAP9-AS1 HGNC:HGNC:44172|Ensembl:ENSG00000251022 +100499183 BAALC-AS1 HGNC:HGNC:50461|Ensembl:ENSG00000247081 +100499191 LOC100499191 - +100499192 LOC100499192 - +100499194 LOC100499194 - +100499223 LOC100499223 - +100499227 USP2-AS1 HGNC:HGNC:48673 +100499251 GMFBP1 HGNC:HGNC:38654 +100499252 ZBTB12BP HGNC:HGNC:37702 +100499258 SNRPBP1 HGNC:HGNC:38665 +100499259 CKS1BP4 HGNC:HGNC:17395 +100499260 AMMEC MIM:300194 +100499261 BTF3P6 HGNC:HGNC:23765 +100499397 DYZ1L1 - +100499398 DYZ1L4 - +100499399 LOC100499399 - +100499405 LINC00987 HGNC:HGNC:48911|Ensembl:ENSG00000237248 +100499409 DYZ1L6 - +100499411 DYZ1L7 - +100499412 DYZ1L16 - +100499416 TOMM22P1 HGNC:HGNC:38736 +100499417 TOMM22P2 HGNC:HGNC:38737 +100499418 MTCYBP1 HGNC:HGNC:38729 +100499435 TEX16P HGNC:HGNC:37957 +100499437 DYZ1L19 - +100499438 DYZ1L20 - +100499442 DYZ1L23 - +100499443 DYZ1L27 - +100499457 MTND2P3 HGNC:HGNC:38727 +100499466 LINC00674 HGNC:HGNC:44355 +100499467 LINC00673 MIM:617079|HGNC:HGNC:44354 +100499468 MTND1P1 HGNC:HGNC:38728 +100499469 MTND6P1 HGNC:HGNC:38730 +100499471 LOC100499471 - +100499481 MED13P1 HGNC:HGNC:38733 +100499483 CCDC180 HGNC:HGNC:29303|Ensembl:ENSG00000197816|Vega:OTTHUMG00000167001 +100499484 LOC100499484 Ensembl:ENSG00000254876 +100499485 SRIP2 HGNC:HGNC:38734 +100499489 LOC100499489 - +100499496 LOC100499496 - +100499497 LOC100499497 - +100499532 ATPLS MIM:107320 +100499563 PTP4A1P2 HGNC:HGNC:41929 +100500719 LOC100500719 - +100500737 PPIAP20 HGNC:HGNC:38037 +100500773 LOC100500773 - +100500797 USP9YP19 HGNC:HGNC:38755 +100500798 USP9YP23 HGNC:HGNC:38759 +100500801 MIR3659 HGNC:HGNC:38882|Ensembl:ENSG00000265596|miRBase:MI0016060 +100500802 MIR3685 HGNC:HGNC:38886|Ensembl:ENSG00000265917|miRBase:MI0016086 +100500803 MIR3919 HGNC:HGNC:38890|Ensembl:ENSG00000263634|miRBase:MI0016425 +100500804 MIR3654 HGNC:HGNC:38896|Ensembl:ENSG00000284135|miRBase:MI0016054 +100500807 MIR374C HGNC:HGNC:38907|Ensembl:ENSG00000283534|miRBase:MI0016684 +100500808 MIR3917 HGNC:HGNC:38911|Ensembl:ENSG00000283938|miRBase:MI0016423 +100500809 MIR23C HGNC:HGNC:38913|Ensembl:ENSG00000264566|miRBase:MI0016010 +100500810 MIR3620 HGNC:HGNC:38917|Ensembl:ENSG00000284163|miRBase:MI0016011 +100500811 MIR3621 HGNC:HGNC:38930|Ensembl:ENSG00000263697|miRBase:MI0016012 +100500812 MIR3677 HGNC:HGNC:38932|Ensembl:ENSG00000266643|miRBase:MI0016078 +100500813 MIR3646 HGNC:HGNC:38935|Ensembl:ENSG00000266151|miRBase:MI0016046 +100500814 MIR3616 HGNC:HGNC:38943|Ensembl:ENSG00000264901|miRBase:MI0016006 +100500815 MIR3687-1 HGNC:HGNC:38946|Ensembl:ENSG00000277437|miRBase:MI0016088 +100500816 MIR3649 HGNC:HGNC:38948|Ensembl:ENSG00000266043|miRBase:MI0016049 +100500817 MIR3612 HGNC:HGNC:38951|Ensembl:ENSG00000265635|miRBase:MI0016002 +100500818 MIR3945 HGNC:HGNC:38954|Ensembl:ENSG00000266698|miRBase:MI0016602 +100500819 MIR3609 HGNC:HGNC:38956|Ensembl:ENSG00000266019|miRBase:MI0015999 +100500820 MIR3655 HGNC:HGNC:38960|Ensembl:ENSG00000284325|miRBase:MI0016055 +100500821 MIR3910-1 HGNC:HGNC:38966|Ensembl:ENSG00000266855|miRBase:MI0016414 +100500822 MIR3937 HGNC:HGNC:38970|Ensembl:ENSG00000263730|miRBase:MI0016593 +100500823 MIR3920 HGNC:HGNC:38974|Ensembl:ENSG00000263885|miRBase:MI0016427 +100500824 MIR3650 HGNC:HGNC:38981|Ensembl:ENSG00000265304|miRBase:MI0016050 +100500825 MIR3660 HGNC:HGNC:38985|Ensembl:ENSG00000264342|miRBase:MI0016061 +100500826 MIR3909 HGNC:HGNC:38987|Ensembl:ENSG00000266320|miRBase:MI0016413 +100500827 MIR3614 HGNC:HGNC:38995|Ensembl:ENSG00000284542|miRBase:MI0016004 +100500828 MIR3619 HGNC:HGNC:38998|Ensembl:ENSG00000266533|miRBase:MI0016009 +100500829 MIR3943 HGNC:HGNC:38888|Ensembl:ENSG00000264069|miRBase:MI0016600 +100500830 MIR550B2 HGNC:HGNC:38910|Ensembl:ENSG00000283461|miRBase:MI0016687 +100500831 MIR3912 HGNC:HGNC:38923|Ensembl:ENSG00000264249|miRBase:MI0016416 +100500832 MIR3658 HGNC:HGNC:38963|Ensembl:ENSG00000283936|miRBase:MI0016058 +100500833 MIR3653 HGNC:HGNC:38971|Ensembl:ENSG00000280968|miRBase:MI0016053 +100500834 MIR3924 HGNC:HGNC:38984|Ensembl:ENSG00000264747|miRBase:MI0016432 +100500835 MIR3907 HGNC:HGNC:38988|Ensembl:ENSG00000265810|miRBase:MI0016410 +100500836 MIR3914-1 HGNC:HGNC:38993|Ensembl:ENSG00000265878|miRBase:MI0016419 +100500837 MIR3606 HGNC:HGNC:38881|Ensembl:ENSG00000284180|miRBase:MI0015996 +100500838 MIR3926-2 HGNC:HGNC:38883|Ensembl:ENSG00000283523|miRBase:MI0016437 +100500839 MIR3686 HGNC:HGNC:38887|Ensembl:ENSG00000263763|miRBase:MI0016087 +100500840 MIR3656 HGNC:HGNC:38889|Ensembl:ENSG00000283704|miRBase:MI0016056 +100500841 MIR3678 HGNC:HGNC:38891|Ensembl:ENSG00000264511|miRBase:MI0016079 +100500842 MIR3652 HGNC:HGNC:38894|Ensembl:ENSG00000284503|miRBase:MI0016052 +100500843 MIR3922 HGNC:HGNC:38895|Ensembl:ENSG00000264295|miRBase:MI0016429 +100500844 MIR3664 HGNC:HGNC:38899|Ensembl:ENSG00000263744|miRBase:MI0016065 +100500845 MIR642B HGNC:HGNC:38902|Ensembl:ENSG00000283212|miRBase:MI0016685 +100500846 MIR3689A HGNC:HGNC:38904|Ensembl:ENSG00000265872|miRBase:MI0016090 +100500847 MIR3615 HGNC:HGNC:38905|Ensembl:ENSG00000284186|miRBase:MI0016005 +100500849 MIR3916 HGNC:HGNC:38912|Ensembl:ENSG00000283881|miRBase:MI0016422 +100500850 MIR3682 HGNC:HGNC:38916|Ensembl:ENSG00000265452|miRBase:MI0016083 +100500851 MIR3918 HGNC:HGNC:38919|Ensembl:ENSG00000265558|miRBase:MI0016424 +100500852 MIR3180-4 HGNC:HGNC:38920|Ensembl:ENSG00000264115|miRBase:MI0016408 +100500853 MIR3605 HGNC:HGNC:38922|Ensembl:ENSG00000284154|miRBase:MI0015995 +100500854 MIR3671 HGNC:HGNC:38925|Ensembl:ENSG00000265996|miRBase:MI0016072 +100500855 MIR3713 HGNC:HGNC:38926|Ensembl:ENSG00000266449|miRBase:MI0016134 +100500856 MIR548Z HGNC:HGNC:38929|Ensembl:ENSG00000266016|miRBase:MI0016688 +100500857 MIR3939 HGNC:HGNC:38931|Ensembl:ENSG00000265828|miRBase:MI0016596 +100500858 MIR3622A HGNC:HGNC:38934|Ensembl:ENSG00000284351|miRBase:MI0016013 +100500859 MIR3921 HGNC:HGNC:38936|Ensembl:ENSG00000264897|miRBase:MI0016428 +100500860 MIR3618 HGNC:HGNC:38937|Ensembl:ENSG00000284140|miRBase:MI0016008 +100500861 MIR3665 HGNC:HGNC:38939|Ensembl:ENSG00000266325|miRBase:MI0016066 +100500862 MIR3648-1 HGNC:HGNC:38941|Ensembl:ENSG00000275708|miRBase:MI0016048 +100500863 MIR548AA1 HGNC:HGNC:38944|Ensembl:ENSG00000207704|miRBase:MI0016689 +100500864 MIR3929 HGNC:HGNC:38945|Ensembl:ENSG00000265641|miRBase:MI0016439 +100500865 MIR3936 HGNC:HGNC:38947|Ensembl:ENSG00000263597|miRBase:MI0016592 +100500866 MIR3941 HGNC:HGNC:38949|Ensembl:ENSG00000265442|miRBase:MI0016598 +100500867 MIR3684 HGNC:HGNC:38950|Ensembl:ENSG00000265213|miRBase:MI0016085 +100500868 MIR3913-2 HGNC:HGNC:38953|Ensembl:ENSG00000283677|miRBase:MI0016418 +100500869 MIR3672 HGNC:HGNC:38957|Ensembl:ENSG00000265456|miRBase:MI0016073 +100500870 MIR3926-1 HGNC:HGNC:38959|Ensembl:ENSG00000266206|miRBase:MI0016434 +100500871 MIR3622B HGNC:HGNC:38961|Ensembl:ENSG00000265075|miRBase:MI0016014 +100500872 MIR3911 HGNC:HGNC:38962|Ensembl:ENSG00000283874|miRBase:MI0016415 +100500873 MIR3934 HGNC:HGNC:38965|Ensembl:ENSG00000266509|miRBase:MI0016590 +100500875 MIR3938 HGNC:HGNC:38972|Ensembl:ENSG00000264013|miRBase:MI0016594 +100500876 MIR3675 HGNC:HGNC:38973|Ensembl:ENSG00000263811|miRBase:MI0016076 +100500877 MIR3923 HGNC:HGNC:38978|Ensembl:ENSG00000265193|miRBase:MI0016430 +100500878 MIR3679 HGNC:HGNC:38979|Ensembl:ENSG00000263813|miRBase:MI0016080 +100500879 MIR3668 HGNC:HGNC:38982|Ensembl:ENSG00000263514|miRBase:MI0016069 +100500880 MIR3662 HGNC:HGNC:38983|Ensembl:ENSG00000283409|miRBase:MI0016063 +100500881 MIR3688-1 HGNC:HGNC:38986|Ensembl:ENSG00000264105|miRBase:MI0016089 +100500882 MIR3667 HGNC:HGNC:38990|Ensembl:ENSG00000264139|miRBase:MI0016068 +100500883 MIR550B1 HGNC:HGNC:38992|Ensembl:ENSG00000283237|miRBase:MI0016686 +100500884 MIR3681 HGNC:HGNC:38994|Ensembl:ENSG00000264089|miRBase:MI0016082 +100500885 MIR3925 HGNC:HGNC:38996|Ensembl:ENSG00000263894|miRBase:MI0016433 +100500886 MIR3683 HGNC:HGNC:38999|Ensembl:ENSG00000266287|miRBase:MI0016084 +100500887 MIR676 HGNC:HGNC:38880|Ensembl:ENSG00000211991|miRBase:MI0016436 +100500888 MIR3940 HGNC:HGNC:38893|Ensembl:ENSG00000284159|miRBase:MI0016597 +100500889 MIR3657 HGNC:HGNC:38906|Ensembl:ENSG00000266370|miRBase:MI0016057 +100500890 MIR3611 HGNC:HGNC:38914|Ensembl:ENSG00000266228|miRBase:MI0016001 +100500891 MIR3935 HGNC:HGNC:38918|Ensembl:ENSG00000265281|miRBase:MI0016591 +100500893 MIR3663 HGNC:HGNC:38958|Ensembl:ENSG00000266782|miRBase:MI0016064 +100500894 MIR3690 HGNC:HGNC:38967|Ensembl:ENSG00000265658|miRBase:MI0016091 +100500895 MIR548AA2 HGNC:HGNC:38921|Ensembl:ENSG00000207688|miRBase:MI0016690 +100500896 MIR3666 HGNC:HGNC:38940|Ensembl:ENSG00000272230|miRBase:MI0016067 +100500897 MIR3617 HGNC:HGNC:38977|Ensembl:ENSG00000266071|miRBase:MI0016007 +100500898 MIR3927 HGNC:HGNC:38901|Ensembl:ENSG00000263861|miRBase:MI0016435 +100500899 MIR3692 HGNC:HGNC:38885|Ensembl:ENSG00000266617|miRBase:MI0016093 +100500900 MIR3691 HGNC:HGNC:38909|Ensembl:ENSG00000265083|miRBase:MI0016092 +100500901 MIR3928 HGNC:HGNC:38933|Ensembl:ENSG00000264141|miRBase:MI0016438 +100500902 MIR3910-2 HGNC:HGNC:38952|Ensembl:ENSG00000283351|miRBase:MI0016431 +100500903 MIR3913-1 HGNC:HGNC:38884|Ensembl:ENSG00000264405|miRBase:MI0016417 +100500904 MIR3942 HGNC:HGNC:38976|Ensembl:ENSG00000265102|miRBase:MI0016599 +100500905 MIR3661 HGNC:HGNC:38892|Ensembl:ENSG00000266751|miRBase:MI0016062 +100500906 MIR3689B HGNC:HGNC:38924|Ensembl:ENSG00000264163|miRBase:MI0016411 +100500907 MIR3150B HGNC:HGNC:38938|Ensembl:ENSG00000284147|miRBase:MI0016426 +100500908 MIR3613 HGNC:HGNC:38964|Ensembl:ENSG00000264864|miRBase:MI0016003 +100500909 MIR3908 HGNC:HGNC:38991|Ensembl:ENSG00000266655|miRBase:MI0016412 +100500910 MIR3670-1 HGNC:HGNC:38997|Ensembl:ENSG00000263918|miRBase:MI0016071 +100500911 MIR3944 HGNC:HGNC:38898|Ensembl:ENSG00000265395|miRBase:MI0016601 +100500912 MIR3674 HGNC:HGNC:38915|Ensembl:ENSG00000283858|miRBase:MI0016075 +100500913 MIR3714 HGNC:HGNC:38928|Ensembl:ENSG00000283885|miRBase:MI0016135 +100500914 MIR3610 HGNC:HGNC:38942|Ensembl:ENSG00000283956|miRBase:MI0016000 +100500915 MIR3915 HGNC:HGNC:38955|Ensembl:ENSG00000263600|miRBase:MI0016420 +100500916 MIR3180-5 HGNC:HGNC:38969|Ensembl:ENSG00000264397|miRBase:MI0016409 +100500917 MIR3680-1 HGNC:HGNC:38989|Ensembl:ENSG00000265462|miRBase:MI0016081 +100500918 MIR3651 HGNC:HGNC:38897|Ensembl:ENSG00000281156|miRBase:MI0016051 +100500919 MIR548Y HGNC:HGNC:38980|Ensembl:ENSG00000263945|miRBase:MI0016595 +100500920 MIR3914-2 HGNC:HGNC:38975|Ensembl:ENSG00000283278|miRBase:MI0016421 +100500934 LOC100500934 - +100500938 CCDC179 HGNC:HGNC:44653|Ensembl:ENSG00000255359|Vega:OTTHUMG00000166074 +100502567 DEL15Q24 MIM:613406 +100502568 STQTL21 MIM:613440 +100502569 BWQTL2 MIM:613459 +100502572 LOC100502572 - +100505381 MMD2 MIM:613318 +100505383 BPIFB5P HGNC:HGNC:42177 +100505385 IQCJ-SCHIP1 HGNC:HGNC:38842|Ensembl:ENSG00000283154 +100505389 DELXP21 MIM:300679 +100505390 AAA2 MIM:609782 +100505391 DEL6Q24Q25 MIM:612863 +100505392 DEL14Q11Q22 MIM:613457 +100505393 DUP16P13.3 MIM:613458 +100505394 EDSS2 MIM:613576 +100505474 LINC01539 HGNC:HGNC:51307|Ensembl:ENSG00000267712 +100505475 SYNE1-AS1 HGNC:HGNC:40793 +100505477 LINC01602 HGNC:HGNC:51634|Ensembl:ENSG00000205293 +100505478 TEX48 HGNC:HGNC:52393|Ensembl:ENSG00000230601|Vega:OTTHUMG00000020542 +100505483 PRKAG2-AS1 HGNC:HGNC:40468 +100505494 ANKRD10-IT1 HGNC:HGNC:39891 +100505495 PCAT19 HGNC:HGNC:49593|Ensembl:ENSG00000267107 +100505498 LOC100505498 - +100505501 LOC100505501 Ensembl:ENSG00000167912 +100505502 LOC100505502 - +100505504 LOC100505504 - +100505506 BANF1P3 HGNC:HGNC:43883 +100505515 LINC01723 HGNC:HGNC:52511|Ensembl:ENSG00000234265 +100505518 EDNRB-AS1 HGNC:HGNC:49045 +100505524 LOC100505524 - +100505530 LINC02520 HGNC:HGNC:53511 +100505532 LINC01301 HGNC:HGNC:50464 +100505534 LOC100505534 - +100505536 ISM1-AS1 HGNC:HGNC:44313 +100505538 RBM26-AS1 HGNC:HGNC:39805|Ensembl:ENSG00000227354 +100505540 SLIT1-AS1 HGNC:HGNC:51198|Ensembl:ENSG00000234855 +100505545 LINC01095 HGNC:HGNC:49220|Ensembl:ENSG00000248809 +100505547 LINC01208 HGNC:HGNC:49639|Ensembl:ENSG00000223715 +100505549 LOC100505549 - +100505555 LOC100505555 - +100505557 GSTM5P1 HGNC:HGNC:4633 +100505561 LINC00866 HGNC:HGNC:45232|Ensembl:ENSG00000227356 +100505566 LINC00578 HGNC:HGNC:43807 +100505570 LOC100505570 - +100505573 INAFM2 HGNC:HGNC:35165|Ensembl:ENSG00000259330 +100505576 LINC00672 MIM:617544|HGNC:HGNC:44353|Ensembl:ENSG00000263874|Vega:OTTHUMG00000178440 +100505583 LINC00838 HGNC:HGNC:44963|Ensembl:ENSG00000261683 +100505585 LOC100505585 Ensembl:ENSG00000076928 +100505588 LOC100505588 Ensembl:ENSG00000236668 +100505591 LRRC3C HGNC:HGNC:40034|Ensembl:ENSG00000204913|Vega:OTTHUMG00000179521 +100505592 GAPLINC HGNC:HGNC:51308|Ensembl:ENSG00000266835 +100505601 PARD3-AS1 HGNC:HGNC:44964|Ensembl:ENSG00000226386 +100505609 LINC02053 HGNC:HGNC:52893|Ensembl:ENSG00000241696 +100505616 SNHG21 HGNC:HGNC:50284|Ensembl:ENSG00000250988 +100505619 LINC00919 HGNC:HGNC:48610|Ensembl:ENSG00000260268 +100505621 C11orf72 HGNC:HGNC:26915|Ensembl:ENSG00000184224 +100505622 LOC100505622 Ensembl:ENSG00000254887 +100505624 GTF3C2-AS1 HGNC:HGNC:40269|Ensembl:ENSG00000234945 +100505625 LINC02102 HGNC:HGNC:52957|Ensembl:ENSG00000248677 +100505633 LINC01133 HGNC:HGNC:49447|Ensembl:ENSG00000224259 +100505635 LOC100505635 Ensembl:ENSG00000235033 +100505636 LINC01024 HGNC:HGNC:49009|Ensembl:ENSG00000245146 +100505641 FGD5-AS1 HGNC:HGNC:40410|Ensembl:ENSG00000225733 +100505642 LOC100505642 - +100505648 RAD51-AS1 HGNC:HGNC:48621|Ensembl:ENSG00000245849 +100505650 LOC100505650 - +100505658 LOC100505658 Ensembl:ENSG00000246422 +100505659 LINC00967 HGNC:HGNC:48725|Ensembl:ENSG00000253138 +100505663 LINC01370 MIM:617038|HGNC:HGNC:50608|Ensembl:ENSG00000237767 +100505664 LOC100505664 Ensembl:ENSG00000230387 +100505666 DCST1-AS1 HGNC:HGNC:41147 +100505676 RRS1-AS1 HGNC:HGNC:50465|Ensembl:ENSG00000246145 +100505678 STARD4-AS1 HGNC:HGNC:44117|Ensembl:ENSG00000246859 +100505679 UBE2Q2L HGNC:HGNC:44656|Ensembl:ENSG00000259511 +100505681 NAPA-AS1 HGNC:HGNC:44118|Ensembl:ENSG00000268061 +100505683 LINC01431 HGNC:HGNC:50744|Ensembl:ENSG00000232645 +100505685 LOC100505685 Ensembl:ENSG00000251249 +100505687 LINC00888 HGNC:HGNC:48575|Ensembl:ENSG00000240024 +100505690 LOC100505690 - +100505692 FTO-IT1 HGNC:HGNC:43758 +100505694 LOC100505694 - +100505696 SH3BP5-AS1 HGNC:HGNC:44501|Ensembl:ENSG00000224660 +100505702 LINC01094 HGNC:HGNC:49219 +100505704 ATP5G1P6 HGNC:HGNC:39509 +100505705 SDIM1 HGNC:HGNC:38749 +100505711 LOC100505711 - +100505715 LOC100505715 Ensembl:ENSG00000267058 +100505716 LOC100505716 Ensembl:ENSG00000223522 +100505718 LINC01592 HGNC:HGNC:51557|Ensembl:ENSG00000253658 +100505724 KRTAP9-7 HGNC:HGNC:18915|Ensembl:ENSG00000180386|Vega:OTTHUMG00000133605 +100505728 LOC100505728 - +100505736 LOC100505736 - +100505738 MIR4458HG HGNC:HGNC:49008|Ensembl:ENSG00000247516 +100505739 LINC01603 HGNC:HGNC:51652 +100505741 SPATA1 HGNC:HGNC:14682|Ensembl:ENSG00000122432 +100505746 ITGB2-AS1 HGNC:HGNC:44304|Ensembl:ENSG00000227039 +100505753 KRTAP16-1 HGNC:HGNC:18916|Ensembl:ENSG00000212657|Vega:OTTHUMG00000133640 +100505755 MTND5P28 HGNC:HGNC:42290 +100505758 PRMT5-AS1 HGNC:HGNC:40533|Ensembl:ENSG00000237054 +100505761 RPARP-AS1 HGNC:HGNC:45238|Ensembl:ENSG00000269609 +100505767 SPDYE18 HGNC:HGNC:51514 +100505768 LINC01364 HGNC:HGNC:50599|Ensembl:ENSG00000227290 +100505771 MHENCR HGNC:HGNC:53110|Ensembl:ENSG00000232442 +100505774 LOC100505774 - +100505776 LINC01541 HGNC:HGNC:51309|Ensembl:ENSG00000260676 +100505782 LOC100505782 Ensembl:ENSG00000234859 +100505783 OSER1-AS1 HGNC:HGNC:48585|Ensembl:ENSG00000223891 +100505785 KIRREL1-IT1 HGNC:HGNC:41412 +100505788 LOC100505788 - +100505795 LOC100505795 Ensembl:ENSG00000233693 +100505796 LOC100505796 - +100505797 LOC100505797 Ensembl:ENSG00000263958 +100505798 LOC100505798 - +100505806 SNHG18 HGNC:HGNC:49007|Ensembl:ENSG00000250786 +100505811 LINC02148 HGNC:HGNC:53008|Ensembl:ENSG00000250427 +100505812 CARD8-AS1 HGNC:HGNC:51408|Ensembl:ENSG00000268001 +100505817 LOC100505817 Ensembl:ENSG00000261780 +100505824 LOC100505824 Ensembl:ENSG00000232265 +100505826 STK4-AS1 HGNC:HGNC:43811|Ensembl:ENSG00000227477 +100505832 PROX1-AS1 HGNC:HGNC:43656 +100505835 LINC01532 HGNC:HGNC:51272|Ensembl:ENSG00000267014 +100505839 SH3PXD2A-AS1 HGNC:HGNC:45242|Ensembl:ENSG00000280693 +100505841 LOC100505841 Vega:OTTHUMG00000162972 +100505845 ROPN1L-AS1 HGNC:HGNC:39984 +100505851 LOC100505851 Ensembl:ENSG00000269289 +100505852 ZNF355P HGNC:HGNC:17218 +100505853 LINC01898 HGNC:HGNC:52717|Ensembl:ENSG00000261194 +100505854 APTR MIM:616048|HGNC:HGNC:44173|Ensembl:ENSG00000214293 +100505855 EIF1P1 HGNC:HGNC:49614 +100505865 LINC00920 HGNC:HGNC:48611 +100505869 CFAP58-AS1 HGNC:HGNC:45243 +100505874 LOC100505874 - +100505875 LINC01088 HGNC:HGNC:49148 +100505876 CEBPZOS HGNC:HGNC:49288|Ensembl:ENSG00000218739|Vega:OTTHUMG00000152162 +100505877 UBE2E2-AS1 HGNC:HGNC:44512|Ensembl:ENSG00000233153 +100505878 LINC02059 HGNC:HGNC:52902 +100505879 KIF25-AS1 HGNC:HGNC:20953|Ensembl:ENSG00000229921 +100505881 MAGI2-AS3 HGNC:HGNC:40862|Ensembl:ENSG00000234456 +100505887 LINC01672 HGNC:HGNC:52460 +100505890 SORCS3-AS1 HGNC:HGNC:45244|Ensembl:ENSG00000226387 +100505892 CCNB1IP1P2 HGNC:HGNC:37694 +100505893 SLIT2-IT1 HGNC:HGNC:41383|Ensembl:ENSG00000248228 +100505894 TMEM161B-AS1 HGNC:HGNC:43839|Ensembl:ENSG00000247828 +100505909 LOC100505909 - +100505911 SOS1-IT1 HGNC:HGNC:41385 +100505912 LOC100505912 - +100505915 LOC100505915 Ensembl:ENSG00000260735 +100505918 LOC100505918 - +100505919 CFL1P7 HGNC:HGNC:39959 +100505920 LINC02036 HGNC:HGNC:52876|Ensembl:ENSG00000225742 +100505921 LOC100505921 - +100505929 LINC01549 HGNC:HGNC:1277|Ensembl:ENSG00000232560 +100505933 ADD3-AS1 HGNC:HGNC:48682 +100505938 LOC100505938 - +100505942 LOC100505942 - +100505945 BTF3L4P1 HGNC:HGNC:39645 +100505948 LINC02184 HGNC:HGNC:53046|Ensembl:ENSG00000260854 +100505953 CICP23 HGNC:HGNC:48833 +100505964 LINC01304 HGNC:HGNC:50472|Ensembl:ENSG00000237401 +100505967 LINC00645 HGNC:HGNC:44299|Ensembl:ENSG00000258548 +100505970 HEXDC-IT1 HGNC:HGNC:43650 +100505975 ENO1-AS1 HGNC:HGNC:40214|Ensembl:ENSG00000230679 +100505978 LOC100505978 Ensembl:ENSG00000257711 +100505982 UBE2V1P13 HGNC:HGNC:52411 +100505984 LINC02478 HGNC:HGNC:53446|Ensembl:ENSG00000115221 +100505985 LOC100505985 - +100505989 SMIM31 HGNC:HGNC:49638|Ensembl:ENSG00000248771|Vega:OTTHUMG00000161261 +100505993 TMEM210 HGNC:HGNC:34059|Ensembl:ENSG00000185863|Vega:OTTHUMG00000020981 +100505994 LUCAT1 HGNC:HGNC:48498|Ensembl:ENSG00000248323 +100505995 LOC100505995 - +100505996 SOX1-OT HGNC:HGNC:42733|Ensembl:ENSG00000224243 +100506000 HSPE1P5 HGNC:HGNC:49324 +100506001 NARF-IT1 HGNC:HGNC:43651 +100506007 RTCA-AS1 HGNC:HGNC:50573 +100506012 PPP5D1 HGNC:HGNC:44209|Ensembl:ENSG00000230510|Vega:OTTHUMG00000183425 +100506013 APELA MIM:615594|HGNC:HGNC:48925|Ensembl:ENSG00000248329|Vega:OTTHUMG00000161255 +100506016 LOC100506016 - +100506020 ARAP1-AS2 HGNC:HGNC:39994 +100506022 LOC100506022 - +100506023 LOC100506023 - +100506025 ISPD-AS1 HGNC:HGNC:48962|Ensembl:ENSG00000229688 +100506033 PTOV1-AS1 HGNC:HGNC:44174|Ensembl:ENSG00000268006 +100506035 LINC00989 HGNC:HGNC:48918|Ensembl:ENSG00000250334 +100506036 LOC100506036 - +100506039 HMGB3P8 HGNC:HGNC:39300 +100506046 GAS5-AS1 HGNC:HGNC:44119|Ensembl:ENSG00000270084 +100506047 LOC100506047 - +100506049 LRRC72 HGNC:HGNC:42972|Ensembl:ENSG00000205858|Vega:OTTHUMG00000152446 +100506050 LINC01005 HGNC:HGNC:48963 +100506054 RNASEH1-AS1 HGNC:HGNC:49289|Ensembl:ENSG00000234171 +100506055 LOC100506055 - +100506058 EIF5A2P1 HGNC:HGNC:51467 +100506060 SMG1P7 HGNC:HGNC:49864|Ensembl:ENSG00000261556 +100506061 BTF3L4P4 HGNC:HGNC:39648 +100506068 DACT3-AS1 HGNC:HGNC:44120|Ensembl:ENSG00000245598 +100506070 RBFADN HGNC:HGNC:48591|Ensembl:ENSG00000261126 +100506071 LOC100506071 Ensembl:ENSG00000258525 +100506076 LOC100506076 - +100506080 HMGA1P4 HGNC:HGNC:39093 +100506082 LOC100506082 Ensembl:ENSG00000254480 +100506083 LOC100506083 Ensembl:ENSG00000261777 +100506084 ARL17B HGNC:HGNC:32387|Ensembl:ENSG00000228696|Vega:OTTHUMG00000178031 +100506085 LINC02275 HGNC:HGNC:53191|Ensembl:ENSG00000248319 +100506098 LOC100506098 Ensembl:ENSG00000233834 +100506099 LOC100506099 - +100506100 LOC100506100 Ensembl:ENSG00000223478 +100506103 LOC100506103 - +100506107 LINC02382 HGNC:HGNC:53305|Ensembl:ENSG00000250968 +100506108 SIX3-AS1 HGNC:HGNC:40532|Ensembl:ENSG00000236502 +100506113 LOC100506113 - +100506114 LOC100506114 - +100506115 SMIM25 HGNC:HGNC:50328 +100506119 LINC01503 HGNC:HGNC:51184|Ensembl:ENSG00000233901 +100506122 LINC02431 HGNC:HGNC:53362|Ensembl:ENSG00000248872 +100506123 LOC100506123 - +100506124 LOC100506124 - +100506125 LOC100506125 Ensembl:ENSG00000257660 +100506126 LINC00867 HGNC:HGNC:45265|Ensembl:ENSG00000232139 +100506127 LOC100506127 Ensembl:ENSG00000179240|Vega:OTTHUMG00000165281 +100506133 LOC100506133 - +100506134 TTC21B-AS1 HGNC:HGNC:41115 +100506142 LOC100506142 Ensembl:ENSG00000250116 +100506144 TMEM35B HGNC:HGNC:40021|Ensembl:ENSG00000243749|Vega:OTTHUMG00000004158 +100506157 SRP54-AS1 HGNC:HGNC:50643 +100506159 LINC02470 HGNC:HGNC:53409|Ensembl:ENSG00000225231 +100506161 TAF1A-AS1 HGNC:HGNC:40573|Ensembl:ENSG00000225265 +100506164 HSFX1 HGNC:HGNC:29603|Ensembl:ENSG00000171116|Vega:OTTHUMG00000022626 +100506169 MTND5P11 HGNC:HGNC:42273 +100506172 LINC01568 HGNC:HGNC:51371|Ensembl:ENSG00000258779 +100506175 LOC100506175 Ensembl:ENSG00000234693 +100506178 LOC100506178 Ensembl:ENSG00000232759 +100506188 LOC100506188 - +100506190 LINC00963 HGNC:HGNC:48716 +100506195 LARGE-AS1 HGNC:HGNC:40336|Ensembl:ENSG00000224973 +100506205 TMEM185AP1 HGNC:HGNC:31717 +100506207 LOC100506207 - +100506211 MIR210HG HGNC:HGNC:39524|Ensembl:ENSG00000247095 +100506215 PAXBP1-AS1 HGNC:HGNC:39603|Ensembl:ENSG00000238197 +100506224 LOC100506224 - +100506229 LINC01093 HGNC:HGNC:49218 +100506233 RAB30-AS1 HGNC:HGNC:48672|Ensembl:ENSG00000246067 +100506235 LOC100506235 - +100506236 LOC100506236 - +100506237 NKX2-1-AS1 HGNC:HGNC:40585|Ensembl:ENSG00000253563 +100506241 LL22NC01-81G9.3 Ensembl:ENSG00000215403 +100506243 KRBOX1 HGNC:HGNC:38708|Ensembl:ENSG00000240747|Vega:OTTHUMG00000186062 +100506244 SUMO2P8 HGNC:HGNC:39018 +100506246 REXO1L9P HGNC:HGNC:44432 +100506248 LOC100506248 - +100506253 LOC100506253 - +100506258 LOC100506258 Ensembl:ENSG00000251364 +100506271 LOC100506271 Ensembl:ENSG00000237862 +100506272 LINC02492 HGNC:HGNC:53476|Ensembl:ENSG00000250590 +100506274 LOC100506274 Ensembl:ENSG00000229727 +100506275 KRBOX1-AS1 HGNC:HGNC:42942|Ensembl:ENSG00000206552 +100506281 LOC100506281 - +100506282 LOC100506282 - +100506286 TBC1D8-AS1 HGNC:HGNC:52782|Ensembl:ENSG00000272902 +100506289 LOC100506289 Ensembl:ENSG00000233760 +100506299 ID2-AS1 HGNC:HGNC:51103|Ensembl:ENSG00000235092 +100506302 LOC100506302 Ensembl:ENSG00000216895 +100506305 LINC00958 HGNC:HGNC:48671|Ensembl:ENSG00000251381 +100506311 HOTAIRM1 HGNC:HGNC:37117|Ensembl:ENSG00000233429 +100506314 LOC100506314 Ensembl:ENSG00000247498 +100506317 LOC100506317 - +100506319 LINC01988 HGNC:HGNC:52820|Ensembl:ENSG00000283036 +100506321 LOC100506321 Ensembl:ENSG00000259118 +100506325 SP2-AS1 HGNC:HGNC:51341|Ensembl:ENSG00000234494 +100506328 LINC01127 HGNC:HGNC:49292 +100506330 WBP1LP2 HGNC:HGNC:43949 +100506334 LINC00649 HGNC:HGNC:44305|Ensembl:ENSG00000237945 +100506343 FAM212B-AS1 HGNC:HGNC:49446|Ensembl:ENSG00000227811 +100506356 ARSD-AS1 HGNC:HGNC:40085 +100506358 LOC100506358 - +100506365 OTUD6B-AS1 HGNC:HGNC:50466|Ensembl:ENSG00000253738 +100506368 LOC100506368 Ensembl:ENSG00000246523 +100506371 LINC02091 HGNC:HGNC:52942 +100506374 EDDM13 HGNC:HGNC:53168 +100506376 TTLL10-AS1 HGNC:HGNC:41159|Ensembl:ENSG00000205231 +100506377 LINC00973 HGNC:HGNC:48868 +100506380 LINC01006 HGNC:HGNC:48971|Ensembl:ENSG00000182648 +100506384 LOC100506384 Ensembl:ENSG00000238194 +100506385 LINC01426 HGNC:HGNC:50734|Ensembl:ENSG00000234380 +100506388 LOC100506388 Ensembl:ENSG00000262061 +100506390 RAP1BP1 HGNC:HGNC:49780 +100506392 SLC16A1-AS1 HGNC:HGNC:49445|Ensembl:ENSG00000226419 +100506393 LINC02398 HGNC:HGNC:53325|Ensembl:ENSG00000256287 +100506394 GAS6-AS2 HGNC:HGNC:43694|Ensembl:ENSG00000272695 +100506400 LOC100506400 - +100506403 LOC100506403 Ensembl:ENSG00000159216 +100506405 LOC100506405 Ensembl:ENSG00000228496 +100506406 LOC100506406 Ensembl:ENSG00000249748 +100506409 ELOVL2-AS1 HGNC:HGNC:44156 +100506411 LOC100506411 - +100506412 LINC00871 HGNC:HGNC:47038|Ensembl:ENSG00000258700 +100506413 DOCK4-AS1 HGNC:HGNC:40876|Ensembl:ENSG00000225572 +100506421 LINC01158 HGNC:HGNC:49513|Ensembl:ENSG00000233639 +100506422 LOC100506422 - +100506424 UBE2L2 HGNC:HGNC:12487 +100506428 CBR3-AS1 HGNC:HGNC:43664|Ensembl:ENSG00000236830 +100506431 LOC100506431 - +100506433 LINC00648 HGNC:HGNC:44302|Ensembl:ENSG00000259129 +100506436 SPAG5-AS1 HGNC:HGNC:41140 +100506443 ITPKB-IT1 HGNC:HGNC:41349 +100506444 LOC100506444 Ensembl:ENSG00000249341 +100506446 LOC100506446 - +100506451 RASSF8-AS1 HGNC:HGNC:48637 +100506457 MIR3681HG HGNC:HGNC:52001|Ensembl:ENSG00000224184 +100506462 SRD5A3-AS1 HGNC:HGNC:44138|Ensembl:ENSG00000249700 +100506465 LINC01234 HGNC:HGNC:49757|Ensembl:ENSG00000249550 +100506469 TMEM147-AS1 HGNC:HGNC:51273|Ensembl:ENSG00000236144 +100506470 LINC01718 HGNC:HGNC:52505|Ensembl:ENSG00000229606 +100506472 LOC100506472 - +100506473 LOC100506473 - +100506474 LOC100506474 Ensembl:ENSG00000225649 +100506475 EGFLAM-AS2 HGNC:HGNC:41168|Ensembl:ENSG00000248572 +100506476 LOC100506476 - +100506489 LOC100506489 Ensembl:ENSG00000240973 +100506492 DSCAM-AS1 HGNC:HGNC:40197|Ensembl:ENSG00000235123 +100506495 LIFR-AS1 HGNC:HGNC:43600|Ensembl:ENSG00000244968 +100506497 LOC100506497 Ensembl:ENSG00000272568 +100506498 LINC02274 HGNC:HGNC:53190|Ensembl:ENSG00000258586 +100506504 PRKCZ-AS1 HGNC:HGNC:40477 +100506506 MORC1-AS1 HGNC:HGNC:40377 +100506514 LOC100506514 - +100506516 LINC01176 HGNC:HGNC:49548|Ensembl:ENSG00000281404 +100506526 C5orf64-AS1 HGNC:HGNC:52969 +100506527 LINC01007 HGNC:HGNC:48973|Ensembl:ENSG00000233123 +100506530 LINC02349 HGNC:HGNC:53271|Ensembl:ENSG00000259284 +100506532 LOC100506532 - +100506540 SPTY2D1-AS1 HGNC:HGNC:44122|Ensembl:ENSG00000247595|Vega:OTTHUMG00000167731 +100506542 LINC01082 MIM:614978|HGNC:HGNC:49125|Ensembl:ENSG00000269186 +100506544 LOC100506544 - +100506548 LOC100506548 - +100506551 LOC100506551 Ensembl:ENSG00000257279 +100506555 NECTIN3-AS1 HGNC:HGNC:40813 +100506557 LOC100506557 Ensembl:ENSG00000280266 +100506563 LOC100506563 - +100506564 THEGL HGNC:HGNC:43771|Ensembl:ENSG00000249693|Vega:OTTHUMG00000160770 +100506569 LOC100506569 - +100506571 LOC100506571 - +100506574 SNRPGP9 HGNC:HGNC:39328 +100506576 LOC100506576 - +100506578 LOC100506578 - +100506581 C16orf95 HGNC:HGNC:40033|Ensembl:ENSG00000260456|Vega:OTTHUMG00000175680 +100506585 LOC100506585 Ensembl:ENSG00000233038 +100506595 HMGB1P40 HGNC:HGNC:39187 +100506599 PPP1R26-AS1 HGNC:HGNC:48717|Ensembl:ENSG00000225361 +100506603 VASH1-AS1 HGNC:HGNC:53215|Ensembl:ENSG00000258301 +100506606 LOC100506606 Ensembl:ENSG00000257176 +100506621 LINC01279 HGNC:HGNC:50335 +100506622 LINC00540 HGNC:HGNC:43673|Ensembl:ENSG00000276476 +100506633 LOC100506633 - +100506634 LOC100506634 - +100506637 PRKAR2A-AS1 HGNC:HGNC:40471|Ensembl:ENSG00000224424 +100506639 LOC100506639 - +100506649 PXN-AS1 HGNC:HGNC:44123|Ensembl:ENSG00000255857 +100506650 C17orf112 HGNC:HGNC:42963 +100506654 LOC100506654 - +100506655 LCMT1-AS2 HGNC:HGNC:51178|Ensembl:ENSG00000260034 +100506658 OCLN MIM:602876|HGNC:HGNC:8104|Ensembl:ENSG00000197822|Vega:OTTHUMG00000099356 +100506660 DDX11-AS1 HGNC:HGNC:44176|Ensembl:ENSG00000245614 +100506664 LOC100506664 - +100506668 NRAV MIM:616207|HGNC:HGNC:48588|Ensembl:ENSG00000248008 +100506672 LOC100506672 - +100506673 ZBTB20-AS2 HGNC:HGNC:42421 +100506674 BRCAT54 - +100506675 LOC100506675 Ensembl:ENSG00000254584 +100506677 AA06 Ensembl:ENSG00000265544 +100506679 LOC100506679 Ensembl:ENSG00000230319 +100506680 SACS-AS1 HGNC:HGNC:39835|Ensembl:ENSG00000229558 +100506681 JARID2-AS1 HGNC:HGNC:40314|Ensembl:ENSG00000235488 +100506682 LOC100506682 Ensembl:ENSG00000226770 +100506685 STMN1P1 HGNC:HGNC:44062 +100506686 IQCH-AS1 HGNC:HGNC:44104|Ensembl:ENSG00000259673 +100506688 LOC100506688 Ensembl:ENSG00000215246 +100506691 LOC100506691 Ensembl:ENSG00000256546 +100506696 PCAT6 HGNC:HGNC:43714|Ensembl:ENSG00000228288 +100506697 LINC00327 HGNC:HGNC:42009|Ensembl:ENSG00000232977 +100506700 LINC02308 HGNC:HGNC:53227|Ensembl:ENSG00000258675 +100506706 CICP19 HGNC:HGNC:48829 +100506710 EBLN3P HGNC:HGNC:50682|Ensembl:ENSG00000281649 +100506712 HNRNPA1P5 HGNC:HGNC:15787 +100506713 ALOX12-AS1 HGNC:HGNC:51342|Ensembl:ENSG00000215067 +100506714 NUP50-AS1 HGNC:HGNC:50502 +100506715 PNKDP1 HGNC:HGNC:49628 +100506718 LOC100506718 - +100506721 MTND1P36 HGNC:HGNC:42086 +100506723 TMSB10P1 HGNC:HGNC:41949 +100506724 LINC00901 HGNC:HGNC:40352|Ensembl:ENSG00000242385 +100506725 LOC100506725 Ensembl:ENSG00000227544 +100506730 LOC100506730 - +100506731 LOC100506731 - +100506733 FAM170B-AS1 HGNC:HGNC:45006|Ensembl:ENSG00000234736 +100506736 SLFN12L MIM:614956|HGNC:HGNC:33920|Ensembl:ENSG00000205045|Vega:OTTHUMG00000167707 +100506737 LINC01589 HGNC:HGNC:51520|Ensembl:ENSG00000238120 +100506742 CASP12 MIM:608633|HGNC:HGNC:19004|Ensembl:ENSG00000204403|Vega:OTTHUMG00000154965 +100506746 AFF1-AS1 HGNC:HGNC:53447|Ensembl:ENSG00000163633 +100506747 LOC100506747 - +100506749 AGAP1-IT1 HGNC:HGNC:41427|Ensembl:ENSG00000235529 +100506753 AZIN1-AS1 HGNC:HGNC:51558 +100506755 MIR497HG HGNC:HGNC:39523|Ensembl:ENSG00000267532 +100506757 LINC00629 HGNC:HGNC:44262 +100506759 OR7E37P HGNC:HGNC:8410 +100506765 IGSF11-AS1 HGNC:HGNC:40777|Ensembl:ENSG00000239877 +100506769 C10orf71-AS1 HGNC:HGNC:45007 +100506775 LINC01353 HGNC:HGNC:50580|Ensembl:ENSG00000231507 +100506776 TRG-AS1 HGNC:HGNC:48974|Ensembl:ENSG00000281103 +100506779 TSPOAP1-AS1 HGNC:HGNC:44148|Ensembl:ENSG00000265148 +100506783 HOXD-AS2 HGNC:HGNC:43756 +100506787 LINC01543 HGNC:HGNC:51310 +100506790 LOC100506790 Ensembl:ENSG00000229015 +100506791 LINC01511 HGNC:HGNC:51200|Ensembl:ENSG00000250584 +100506795 LINC01354 HGNC:HGNC:50581|Ensembl:ENSG00000231768 +100506797 LOC100506797 - +100506801 LOC100506801 Ensembl:ENSG00000231105 +100506804 LOC100506804 - +100506810 LINC01132 HGNC:HGNC:49444|Ensembl:ENSG00000227630 +100506811 LOC100506811 - +100506815 FOXP1-IT1 HGNC:HGNC:41335 +100506826 MYLK-AS1 HGNC:HGNC:42440|Ensembl:ENSG00000239523 +100506827 LINC02475 HGNC:HGNC:53418|Ensembl:ENSG00000251350 +100506834 GAS1RR HGNC:HGNC:52261|Ensembl:ENSG00000226237 +100506835 LINC00840 HGNC:HGNC:44987|Ensembl:ENSG00000226808 +100506840 IQCF4 Ensembl:ENSG00000224792 +100506844 LOC100506844 - +100506851 LOC100506851 - +100506858 LOC100506858 - +100506860 LINC00513 HGNC:HGNC:43566 +100506866 TTN-AS1 HGNC:HGNC:44124|Ensembl:ENSG00000237298 +100506869 LOC100506869 Ensembl:ENSG00000258231 +100506872 RNF7P1 HGNC:HGNC:43425 +100506874 LINC00933 HGNC:HGNC:48625 +100506881 MKLN1-AS HGNC:HGNC:40374|Ensembl:ENSG00000236753 +100506885 LOC100506885 Ensembl:ENSG00000228412 +100506888 ELOA3D HGNC:HGNC:33511|Ensembl:ENSG00000274744|Vega:OTTHUMG00000180382 +100506895 LUARIS HGNC:HGNC:40992|Ensembl:ENSG00000231638 +100506897 DAPK1-IT1 HGNC:HGNC:43591 +100506898 MAGOH2P HGNC:HGNC:30148 +100506901 LL0XNC01-250H12.3 - +100506907 CCDC37-AS1 HGNC:HGNC:49641|Ensembl:ENSG00000249833 +100506911 LOC100506911 - +100506915 CHRM3-AS2 HGNC:HGNC:43725|Ensembl:ENSG00000233355 +100506916 CYP4F9P HGNC:HGNC:39940 +100506922 LOC100506922 - +100506925 HNRNPA1P31 HGNC:HGNC:39549 +100506929 LOC100506929 - +100506930 LINC00665 HGNC:HGNC:44323|Ensembl:ENSG00000232677 +100506937 LOC100506937 Ensembl:ENSG00000225881 +100506938 S100A11P4 HGNC:HGNC:37841 +100506939 PRKG1-AS1 HGNC:HGNC:45029 +100506946 LOC100506946 - +100506953 FABP7P1 HGNC:HGNC:41951 +100506955 LOC100506955 - +100506963 ELOA-AS1 HGNC:HGNC:50582|Ensembl:ENSG00000236810 +100506965 PWAR6 HGNC:HGNC:49129 +100506974 LOC100506974 - +100506985 LOC100506985 - +100506990 LOC100506990 - +100506994 PTPRG-AS1 HGNC:HGNC:44638|Ensembl:ENSG00000241472 +100506999 LINC02318 HGNC:HGNC:53237|Ensembl:ENSG00000258390 +100507002 LOC100507002 - +100507003 GFY HGNC:HGNC:44663|Ensembl:ENSG00000261949|Vega:OTTHUMG00000177824 +100507006 LOC100507006 - +100507008 LINC00844 HGNC:HGNC:45031 +100507012 BMPR1B-AS1 HGNC:HGNC:50864 +100507027 MRLN MIM:616246|HGNC:HGNC:48649|Ensembl:ENSG00000227877|Vega:OTTHUMG00000018282 +100507032 TMCC1-AS1 HGNC:HGNC:49060|Ensembl:ENSG00000271270 +100507034 PITRM1-AS1 HGNC:HGNC:44675|Ensembl:ENSG00000237399 +100507040 LINC00427 HGNC:HGNC:42762 +100507043 TUNAR MIM:615719|HGNC:HGNC:44088|Ensembl:ENSG00000250366|Vega:OTTHUMG00000171392 +100507044 NBPF5P MIM:613995|HGNC:HGNC:24491 +100507046 HSPE1P3 HGNC:HGNC:49322 +100507050 TPBGL HGNC:HGNC:44159|Ensembl:ENSG00000261594|Vega:OTTHUMG00000165441 +100507053 LOC100507053 Ensembl:ENSG00000246090 +100507055 LRCOL1 HGNC:HGNC:44160|Ensembl:ENSG00000204583|Vega:OTTHUMG00000168043 +100507056 CCAT1 HGNC:HGNC:45128 +100507057 MELTF-AS1 HGNC:HGNC:40373|Ensembl:ENSG00000228109 +100507058 LINC00845 HGNC:HGNC:45033|Ensembl:ENSG00000227244 +100507059 LINC00703 HGNC:HGNC:44677|Ensembl:ENSG00000224382 +100507062 PSMD6-AS2 HGNC:HGNC:44125|Ensembl:ENSG00000239653 +100507064 TEX26-AS1 HGNC:HGNC:42784|Ensembl:ENSG00000224743 +100507065 LOC100507065 - +100507066 CLIP1-AS1 HGNC:HGNC:48586 +100507067 GOLGA8UP HGNC:HGNC:44411 +100507071 LOC100507071 Ensembl:ENSG00000254064 +100507073 LINC01798 HGNC:HGNC:52588|Ensembl:ENSG00000232046 +100507083 LOC100507083 - +100507086 DLG1-AS1 HGNC:HGNC:44154|Ensembl:ENSG00000227375 +100507091 PITPNM2-AS1 HGNC:HGNC:53391|Ensembl:ENSG00000251497 +100507096 GIMD1 HGNC:HGNC:44141|Ensembl:ENSG00000250298|Vega:OTTHUMG00000161071 +100507097 ATP5G2P3 HGNC:HGNC:42187 +100507098 ADAMTS9-AS2 HGNC:HGNC:42435|Ensembl:ENSG00000241684 +100507099 FRY-AS1 HGNC:HGNC:39725 +100507102 COX20P1 HGNC:HGNC:31435 +100507103 LOC100507103 Ensembl:ENSG00000230537 +100507113 ZNF638-IT1 HGNC:HGNC:41434 +100507114 LINC00445 HGNC:HGNC:42782|Ensembl:ENSG00000236036 +100507117 ASAP1-IT2 HGNC:HGNC:48917|Ensembl:ENSG00000280543 +100507118 PRC1-AS1 HGNC:HGNC:48587|Ensembl:ENSG00000258725 +100507124 HMGN1P25 HGNC:HGNC:39369 +100507125 ERHP1 HGNC:HGNC:41916 +100507127 LINC00707 HGNC:HGNC:44691|Ensembl:ENSG00000238266 +100507135 SPART-AS1 HGNC:HGNC:39933|Ensembl:ENSG00000120664 +100507140 LINC01792 HGNC:HGNC:52582|Ensembl:ENSG00000237166 +100507143 LINC00708 HGNC:HGNC:44694|Ensembl:ENSG00000232170 +100507144 LOC100507144 Ensembl:ENSG00000255521 +100507156 LOC100507156 Ensembl:ENSG00000253837 +100507157 MTND1P30 HGNC:HGNC:42079 +100507163 LINC00709 HGNC:HGNC:44700 +100507170 CT47A12 HGNC:HGNC:33292|Ensembl:ENSG00000226685|Vega:OTTHUMG00000188843 +100507171 BOLA3-AS1 HGNC:HGNC:42922|Ensembl:ENSG00000225439 +100507173 LINC01012 HGNC:HGNC:48986|Ensembl:ENSG00000281706 +100507175 LINC02408 HGNC:HGNC:53337|Ensembl:ENSG00000203585 +100507178 SLFNL1-AS1 HGNC:HGNC:44126|Ensembl:ENSG00000281207 +100507191 LOC100507191 - +100507194 LINC02525 HGNC:HGNC:53545|Ensembl:ENSG00000230269 +100507195 LINC02384 HGNC:HGNC:53308|Ensembl:ENSG00000251301 +100507201 LINC01815 HGNC:HGNC:52619 +100507203 SMLR1 HGNC:HGNC:44670|Ensembl:ENSG00000256162|Vega:OTTHUMG00000176259 +100507205 LOC100507205 - +100507206 LINC00943 HGNC:HGNC:48639 +100507210 LINC02000 HGNC:HGNC:52835|Ensembl:ENSG00000243832 +100507217 LINC01578 HGNC:HGNC:48626 +100507218 RNF157-AS1 HGNC:HGNC:44127|Ensembl:ENSG00000267128 +100507221 LOC100507221 - +100507231 LOC100507231 - +100507240 VWA8-AS1 HGNC:HGNC:44270|Ensembl:ENSG00000278338 +100507244 MAMDC2-AS1 HGNC:HGNC:48719|Ensembl:ENSG00000204706 +100507246 SNHG16 HGNC:HGNC:44352|Ensembl:ENSG00000163597 +100507249 C8orf17 MIM:616992|HGNC:HGNC:17737 +100507250 LOC100507250 Ensembl:ENSG00000247363 +100507251 CICP6 HGNC:HGNC:37755 +100507254 LINC01013 HGNC:HGNC:48987 +100507257 MEG9 HGNC:HGNC:43874|Ensembl:ENSG00000223403 +100507261 MIR670HG HGNC:HGNC:49204|Ensembl:ENSG00000235661 +100507266 STX18-AS1 HGNC:HGNC:48877|Ensembl:ENSG00000247708 +100507267 LINC01187 HGNC:HGNC:49575 +100507274 LINC01210 HGNC:HGNC:49642|Ensembl:ENSG00000239513 +100507277 LINC02314 HGNC:HGNC:53233|Ensembl:ENSG00000259082 +100507283 LOC100507283 Ensembl:ENSG00000245498 +100507290 ZNF865 HGNC:HGNC:38705|Ensembl:ENSG00000261221|Vega:OTTHUMG00000177108 +100507291 LOC100507291 Ensembl:ENSG00000248932 +100507297 TMEM44-AS1 HGNC:HGNC:44272 +100507299 SMC5-AS1 HGNC:HGNC:48718 +100507300 ALKBH3-AS1 HGNC:HGNC:48670|Ensembl:ENSG00000244926 +100507303 SNHG19 HGNC:HGNC:49574|Ensembl:ENSG00000260260 +100507308 TARID MIM:616058|HGNC:HGNC:50506|Ensembl:ENSG00000227954 +100507316 MINCR HGNC:HGNC:51653|Ensembl:ENSG00000253716 +100507321 ERVK13-1 HGNC:HGNC:27548 +100507331 ZSWIM8-AS1 HGNC:HGNC:45103|Ensembl:ENSG00000272589 +100507334 LOC100507334 Ensembl:ENSG00000261760 +100507336 LOC100507336 - +100507341 SMIM18 HGNC:HGNC:42973|Ensembl:ENSG00000253457|Vega:OTTHUMG00000163839 +100507346 LOC100507346 - +100507347 VIM-AS1 HGNC:HGNC:44879|Ensembl:ENSG00000229124 +100507351 LOC100507351 - +100507354 CDC42P5 HGNC:HGNC:44429 +100507357 RPL23AP86 HGNC:HGNC:51577 +100507361 PCNPP5 HGNC:HGNC:41977 +100507362 LINC01015 HGNC:HGNC:48988|Ensembl:ENSG00000224582 +100507373 LOC100507373 Ensembl:ENSG00000267169 +100507377 LOC100507377 Ensembl:ENSG00000251138 +100507379 LOC100507379 - +100507381 KCNQ5-IT1 HGNC:HGNC:41354|Ensembl:ENSG00000233844 +100507384 LOC100507384 Ensembl:ENSG00000254519 +100507387 LOC100507387 Ensembl:ENSG00000182230 +100507388 LOC100507388 Ensembl:ENSG00000249717 +100507389 LOC100507389 Ensembl:ENSG00000243818 +100507391 LINC01968 HGNC:HGNC:52794|Ensembl:ENSG00000237222 +100507392 SENCR MIM:615815|HGNC:HGNC:44177|Ensembl:ENSG00000254703 +100507393 LOC100507393 - +100507395 LOC100507395 - +100507398 INTS6-AS1 HGNC:HGNC:42691|Ensembl:ENSG00000236778 +100507401 LRP4-AS1 HGNC:HGNC:44128|Ensembl:ENSG00000247675 +100507403 LOC100507403 - +100507404 TMLHE-AS1 HGNC:HGNC:44261|Ensembl:ENSG00000224533 +100507406 LINC02539 HGNC:HGNC:53572|Ensembl:ENSG00000234956 +100507410 C1QTNF1-AS1 HGNC:HGNC:44351|Ensembl:ENSG00000265096 +100507412 LOC100507412 - +100507415 FAM220CP HGNC:HGNC:43640 +100507419 MMP25-AS1 HGNC:HGNC:51372 +100507420 LINC01605 HGNC:HGNC:51654 +100507421 TMEM178B HGNC:HGNC:44112|Ensembl:ENSG00000261115|Vega:OTTHUMG00000172737 +100507422 LOC100507422 - +100507423 MKNK1-AS1 HGNC:HGNC:44129|Ensembl:ENSG00000269956 +100507428 LINC00458 HGNC:HGNC:42807|Ensembl:ENSG00000234787 +100507431 LINC02551 HGNC:HGNC:53586 +100507433 ZNF571-AS1 HGNC:HGNC:44324|Ensembl:ENSG00000267470 +100507435 DLGAP2-AS1 HGNC:HGNC:50467|Ensembl:ENSG00000253267 +100507436 MICA MIM:600169|HGNC:HGNC:7090|Ensembl:ENSG00000204520|IMGT/GENE-DB:MICA|Vega:OTTHUMG00000031073 +100507437 LOC100507437 Ensembl:ENSG00000251602 +100507443 LOC100507443 - +100507444 PPP1R2P1 HGNC:HGNC:9289 +100507458 ZNF213-AS1 HGNC:HGNC:50505 +100507459 NRSN2-AS1 HGNC:HGNC:51222 +100507460 LOC100507460 - +100507461 LINC02032 HGNC:HGNC:52866|Ensembl:ENSG00000241131 +100507462 GVQW2 HGNC:HGNC:51715|Ensembl:ENSG00000279968|Vega:OTTHUMG00000189248 +100507463 PSMB8-AS1 HGNC:HGNC:39758|Ensembl:ENSG00000204261 +100507464 LOC100507464 Ensembl:ENSG00000253380 +100507466 DPH6-AS1 HGNC:HGNC:44147|Ensembl:ENSG00000248079 +100507468 LOC100507468 - +100507470 GRID1-AS1 HGNC:HGNC:44131|Ensembl:ENSG00000234942 +100507472 LOC100507472 - +100507475 IDH1-AS1 HGNC:HGNC:40292|Ensembl:ENSG00000231908 +100507477 LOC100507477 Ensembl:ENSG00000236013 +100507480 LOC100507480 - +100507487 LOC100507487 Ensembl:ENSG00000251432 +100507489 LINC01277 HGNC:HGNC:50334 +100507490 ZNF859P HGNC:HGNC:34507 +100507495 SDCBP2-AS1 HGNC:HGNC:44314|Ensembl:ENSG00000234684 +100507500 EGFR-AS1 HGNC:HGNC:40207|Ensembl:ENSG00000224057 +100507501 LINC01569 HGNC:HGNC:51380|Ensembl:ENSG00000262468 +100507506 LOC100507506 Ensembl:ENSG00000234817 +100507507 LOC100507507 - +100507513 LOC100507513 - +100507516 LOC100507516 - +100507521 LOC100507521 Ensembl:ENSG00000255553 +100507524 ARHGEF26-AS1 HGNC:HGNC:41048|Ensembl:ENSG00000243069 +100507526 SMG1P4 HGNC:HGNC:49861 +100507527 THEG5 - +100507528 LINC00613 HGNC:HGNC:44060|Ensembl:ENSG00000248330 +100507530 MCPH1-AS1 HGNC:HGNC:51655 +100507533 SOX21-AS1 HGNC:HGNC:39807|Ensembl:ENSG00000227640 +100507534 LINC02192 HGNC:HGNC:53054|Ensembl:ENSG00000261325 +100507537 DWORF MIM:616891|Ensembl:ENSG00000240045|Vega:OTTHUMG00000158471 +100507540 LINC01504 HGNC:HGNC:51185|Ensembl:ENSG00000225434 +100507547 LOC100507547 Ensembl:ENSG00000204314 +100507548 LOC100507548 - +100507549 HMGB3P32 HGNC:HGNC:39335 +100507551 LOC100507551 - +100507554 LOC100507554 - +100507557 LOC100507557 Ensembl:ENSG00000235652 +100507560 LOC100507560 - +100507561 LOC100507561 - +100507562 LOC100507562 - +100507564 LOC100507564 Ensembl:ENSG00000226754 +100507567 RAB11B-AS1 HGNC:HGNC:44178|Ensembl:ENSG00000269386 +100507582 BHLHE40-AS1 HGNC:HGNC:44471|Ensembl:ENSG00000235831 +100507584 LINC01016 HGNC:HGNC:48991|Ensembl:ENSG00000249346 +100507586 LOC100507586 - +100507588 TGFBR3L HGNC:HGNC:44152|Ensembl:ENSG00000260001|Vega:OTTHUMG00000175717 +100507589 NAGPA-AS1 HGNC:HGNC:44184 +100507599 LOC100507599 - +100507600 LOC100507600 Ensembl:ENSG00000226806 +100507602 TRIM52-AS1 HGNC:HGNC:49006|Ensembl:ENSG00000248275 +100507605 LINC00837 HGNC:HGNC:27436|Ensembl:ENSG00000235824 +100507606 LOC100507606 - +100507607 NPIPB9 HGNC:HGNC:41987|Ensembl:ENSG00000196993|Vega:OTTHUMG00000170452 +100507608 KRTAP9-6 HGNC:HGNC:18914|Ensembl:ENSG00000212659|Vega:OTTHUMG00000133600 +100507612 LINC00402 HGNC:HGNC:42732 +100507616 LINC02397 HGNC:HGNC:53323 +100507617 PPP1R14BP3 HGNC:HGNC:16330 +100507629 LINC00658 HGNC:HGNC:44315|Ensembl:ENSG00000226995 +100507632 LINC00968 HGNC:HGNC:48727|Ensembl:ENSG00000246430 +100507633 TNKS2-AS1 HGNC:HGNC:45173|Ensembl:ENSG00000228701 +100507634 LOC100507634 - +100507639 LINC02432 HGNC:HGNC:53363 +100507642 LOC100507642 - +100507648 CICP15 HGNC:HGNC:38549 +100507650 RNF212B HGNC:HGNC:20438|Ensembl:ENSG00000215277|Vega:OTTHUMG00000149918 +100507651 LINC01606 HGNC:HGNC:51656|Ensembl:ENSG00000253301 +100507657 LINC02554 HGNC:HGNC:53594|Ensembl:ENSG00000226741 +100507661 LINC02082 HGNC:HGNC:52931|Ensembl:ENSG00000242268 +100507670 LOC100507670 Ensembl:ENSG00000232671 +100507674 MARK2P9 HGNC:HGNC:39800 +100507679 MUC22 MIM:613917|HGNC:HGNC:39755|Ensembl:ENSG00000261272|Vega:OTTHUMG00000133673 +100507703 LOC100507703 - +100507747 LOC100507747 Ensembl:ENSG00000283199|Vega:OTTHUMG00000191740 +100508046 LOC100508046 Ensembl:ENSG00000275563 +100508120 GMDS-AS1 HGNC:HGNC:48993 +100508631 LOC100508631 Ensembl:ENSG00000261761 +100509370 LOC100509370 - +100509620 LOC100509620 Ensembl:ENSG00000259916|Vega:OTTHUMG00000175552 +100509857 KRT8P4 HGNC:HGNC:31057 +100509894 CPB2-AS1 HGNC:HGNC:39898|Ensembl:ENSG00000235903 +100509927 HIST1H2APS6 HGNC:HGNC:42647 +100510707 TBC1D3J HGNC:HGNC:51247 +100510709 LOC100510709 - +100510710 LOC100510710 - +100526416 AK4P5 HGNC:HGNC:39068 +100526648 MIR1273E HGNC:HGNC:50833|Ensembl:ENSG00000265031|miRBase:MI0016059 +100526656 GNG10P1 HGNC:HGNC:49502 +100526664 LY75-CD302 HGNC:HGNC:38828|Ensembl:ENSG00000248672|Vega:OTTHUMG00000161661 +100526693 ARPC4-TTLL3 HGNC:HGNC:38830|Ensembl:ENSG00000250151|Vega:OTTHUMG00000161408 +100526694 MSANTD3-TMEFF1 HGNC:HGNC:38838 +100526735 CRYZP2 HGNC:HGNC:49203 +100526736 LOC100526736 - +100526737 RBM14-RBM4 HGNC:HGNC:38840|Ensembl:ENSG00000248643|Vega:OTTHUMG00000160813 +100526738 SUMO2P5 HGNC:HGNC:39015 +100526739 CENPS-CORT HGNC:HGNC:38843|Ensembl:ENSG00000251503|Vega:OTTHUMG00000162436 +100526740 ATP5J2-PTCD1 HGNC:HGNC:38844|Ensembl:ENSG00000248919|Vega:OTTHUMG00000160779 +100526741 DEL8Q13 MIM:600383 +100526742 DEL16P12.1P11.2 MIM:613604 +100526743 DUP17Q23.1Q23.2 MIM:613618 +100526760 ABHD14A-ACY1 HGNC:HGNC:38856|Ensembl:ENSG00000114786|Vega:OTTHUMG00000166447 +100526761 CCDC169-SOHLH2 HGNC:HGNC:38866|Ensembl:ENSG00000250709|Vega:OTTHUMG00000162258 +100526767 RNF103-CHMP3 HGNC:HGNC:38847|Ensembl:ENSG00000249884|Vega:OTTHUMG00000160822 +100526771 TMPRSS4-AS1 HGNC:HGNC:44179|Ensembl:ENSG00000255274 +100526772 TMEM110-MUSTN1 HGNC:HGNC:38834|Ensembl:ENSG00000248592|Vega:OTTHUMG00000160756 +100526773 EPPIN-WFDC6 HGNC:HGNC:38825|Ensembl:ENSG00000249139|Vega:OTTHUMG00000161548 +100526776 CSNK1A1P3 HGNC:HGNC:38669 +100526783 C15orf38-AP3S2 HGNC:HGNC:38824|Ensembl:ENSG00000250021|Vega:OTTHUMG00000162161 +100526790 TST1 MIM:613636 +100526791 DEL19P13.13 MIM:613638 +100526793 CKS1BP5 HGNC:HGNC:17640 +100526794 NT5C1B-RDH14 HGNC:HGNC:38831|Ensembl:ENSG00000250741|Vega:OTTHUMG00000161546 +100526820 CAHM MIM:615930|HGNC:HGNC:42860|Ensembl:ENSG00000270419 +100526823 TST2 MIM:613637 +100526825 INMT-MINDY4 HGNC:HGNC:41995|Ensembl:ENSG00000254959|Vega:OTTHUMG00000022897 +100526830 SLX1A-SULT1A3 HGNC:HGNC:44437|Ensembl:ENSG00000213599 +100526831 SLX1B-SULT1A4 HGNC:HGNC:48353|Ensembl:ENSG00000260280 +100526832 PHOSPHO2-KLHL23 Ensembl:ENSG00000213160|Vega:OTTHUMG00000132213 +100526833 SEPT5-GP1BB Ensembl:ENSG00000184702|Vega:OTTHUMG00000150399 +100526835 FPGT-TNNI3K HGNC:HGNC:42952|Ensembl:ENSG00000259030|Vega:OTTHUMG00000166281 +100526836 BLOC1S5-TXNDC5 HGNC:HGNC:42001|Ensembl:ENSG00000259040|Vega:OTTHUMG00000171453 +100526837 EEF1E1-BLOC1S5 HGNC:HGNC:49187 +100526838 LOC100526838 - +100526839 LOC100526839 - +100526840 LOC100526840 - +100526841 LOC100526841 - +100526842 RPL17-C18orf32 HGNC:HGNC:44661|Ensembl:ENSG00000215472|Vega:OTTHUMG00000179689 +100527943 TGIF2-C20orf24 HGNC:HGNC:44664|Ensembl:ENSG00000259399|Vega:OTTHUMG00000032382 +100527945 NDUFA12P1 HGNC:HGNC:39419 +100527946 PDCD5P1 HGNC:HGNC:49885 +100527947 PDCD5P2 HGNC:HGNC:49886 +100527948 HMGB1P27 HGNC:HGNC:39118 +100527949 GIMAP1-GIMAP5 HGNC:HGNC:51257|Ensembl:ENSG00000281887|Vega:OTTHUMG00000189885 +100527950 GJA9-MYCBP - +100527960 MROH7-TTC4 HGNC:HGNC:49180|Ensembl:ENSG00000271723|Vega:OTTHUMG00000185328 +100527963 PMF1-BGLAP HGNC:HGNC:42953|Ensembl:ENSG00000260238|Vega:OTTHUMG00000014817 +100527964 LHX4-AS1 HGNC:HGNC:40982|Ensembl:ENSG00000230124 +100527978 TMEM56-RWDD3 HGNC:HGNC:49388|Ensembl:ENSG00000271092|Vega:OTTHUMG00000184628 +100528006 DPPA5P3 HGNC:HGNC:44688 +100528007 BORCS7-ASMT HGNC:HGNC:49183 +100528016 TMX2-CTNND1 HGNC:HGNC:41992 +100528017 SAA2-SAA4 HGNC:HGNC:39550|Ensembl:ENSG00000255071|Vega:OTTHUMG00000166482 +100528018 ARL2-SNX15 HGNC:HGNC:49197|Ensembl:ENSG00000273003|Vega:OTTHUMG00000185851 +100528019 HSPB2-C11orf52 HGNC:HGNC:41996|Ensembl:ENSG00000254445|Vega:OTTHUMG00000166887 +100528020 FAM187A HGNC:HGNC:35153 +100528021 ST20-MTHFS HGNC:HGNC:44655|Ensembl:ENSG00000259332|Vega:OTTHUMG00000172077 +100528022 BLOC1S1-RDH5 - +100528023 PPR1 MIM:132100 +100528024 DEL11P13 MIM:194072 +100528025 SXGQTL1 MIM:613498 +100528026 DEL4Q21 MIM:613509 +100528027 RJBS MIM:613658 +100528030 POC1B-GALNT4 HGNC:HGNC:42957|Ensembl:ENSG00000259075|Vega:OTTHUMG00000171333 +100528031 FKBP1A-SDCBP2 HGNC:HGNC:41997 +100528032 KLRC4-KLRK1 HGNC:HGNC:48357 +100528061 LOC100528061 - +100528062 ARMCX5-GPRASP2 HGNC:HGNC:42000 +100528063 LOC100528063 - +100528064 NEDD8-MDP1 HGNC:HGNC:39551|Ensembl:ENSG00000255526|Vega:OTTHUMG00000167107 +100529052 LOC100529052 - +100529063 BCL2L2-PABPN1 HGNC:HGNC:42959|Ensembl:ENSG00000258643|Vega:OTTHUMG00000171498 +100529067 SERF2-C15ORF63 - +100529097 RPL36A-HNRNPH2 HGNC:HGNC:48349 +100529099 DUP2Q31.1 MIM:613681 +100529111 LOC100529111 - +100529118 DELXP22.11 MIM:300830 +100529119 SCLL MIM:613523 +100529141 LGTN MIM:151625|HGNC:HGNC:39494 +100529144 CORO7-PAM16 HGNC:HGNC:44424|Ensembl:ENSG00000103426|Vega:OTTHUMG00000177664 +100529145 TEN1-CDK3 HGNC:HGNC:44420|Ensembl:ENSG00000261408 +100529146 DER22T11-22 MIM:609029 +100529147 MMRFCGU MIM:613680 +100529148 MDNS MIM:613689 +100529149 DER22T8-22 MIM:613700 +100529151 IBD11 MIM:191390 +100529207 RAD51L3-RFFL - +100529209 RNASEK-C17orf49 HGNC:HGNC:44419|Ensembl:ENSG00000161939 +100529211 TMEM256-PLSCR3 HGNC:HGNC:49186 +100529215 ZNF559-ZNF177 HGNC:HGNC:42964|Ensembl:ENSG00000188629|Ensembl:ENSG00000270011|Vega:OTTHUMG00000179943|Vega:OTTHUMG00000183958 +100529221 DEL6Q11Q14 MIM:613544 +100529222 STQTL23 MIM:613548 +100529223 STQTL24 MIM:613549 +100529224 FWS MIM:613606 +100529226 DUP17Q21.31 MIM:613533 +100529227 STQTL22 MIM:613547 +100529228 TRIP4Q32.1Q32.2 MIM:613603 +100529229 FAME3 MIM:613608 +100529230 LGMD1H MIM:613530|HGNC:HGNC:38505 +100529231 MACST MIM:613545 +100529239 RPS10-NUDT3 HGNC:HGNC:49181|Ensembl:ENSG00000270800|Vega:OTTHUMG00000185089 +100529240 ZNF816-ZNF321P HGNC:HGNC:38879|Ensembl:ENSG00000221874|Vega:OTTHUMG00000167759 +100529241 HSPE1-MOB4 HGNC:HGNC:49184|Ensembl:ENSG00000270757|Vega:OTTHUMG00000184877 +100529242 DEL1Q41Q42 MIM:612530 +100529243 DEL2P12P11.2 MIM:613564 +100529251 CKLF-CMTM1 HGNC:HGNC:39977|Ensembl:ENSG00000254788|Vega:OTTHUMG00000167106 +100529257 SYNJ2BP-COX16 HGNC:HGNC:48350|Ensembl:ENSG00000258644|Vega:OTTHUMG00000171239 +100529261 CHURC1-FNTB HGNC:HGNC:42960|Ensembl:ENSG00000125954|Vega:OTTHUMG00000170219 +100529262 MIA-RAB4B HGNC:HGNC:48352 +100529264 RAB4B-EGLN2 HGNC:HGNC:44465 +100529855 ZNF625-ZNF20 HGNC:HGNC:48368 +100532724 NPHP3-ACAD11 HGNC:HGNC:48351|Ensembl:ENSG00000274810|Vega:OTTHUMG00000187276 +100532726 NDUFC2-KCTD14 HGNC:HGNC:42956|Ensembl:ENSG00000259112|Vega:OTTHUMG00000171802 +100532727 DDX11L12 - +100532731 COMMD3-BMI1 HGNC:HGNC:48326|Ensembl:ENSG00000269897|Vega:OTTHUMG00000184031 +100532732 MSH5-SAPCD1 HGNC:HGNC:41994|Ensembl:ENSG00000255152|Vega:OTTHUMG00000031139 +100532735 INO80B-WBP1 HGNC:HGNC:49199|Ensembl:ENSG00000274049|Vega:OTTHUMG00000187278 +100532736 MINOS1-NBL1 HGNC:HGNC:48338|Ensembl:ENSG00000270136|Vega:OTTHUMG00000183956 +100532737 ATP6V1G2-DDX39B HGNC:HGNC:41999|Ensembl:ENSG00000254870|Vega:OTTHUMG00000031200 +100532738 DEL1P32P31 MIM:613735 +100532742 PIR-FIGF - +100532746 PPT2-EGFL8 HGNC:HGNC:48343|Ensembl:ENSG00000258388|Vega:OTTHUMG00000171245 +100532749 LOC100532749 - +100533105 C8orf44-SGK3 HGNC:HGNC:48354|Ensembl:ENSG00000270024|Vega:OTTHUMG00000183957 +100533106 ZHX1-C8orf76 HGNC:HGNC:42975|Ensembl:ENSG00000259305|Vega:OTTHUMG00000165087 +100533107 RTEL1-TNFRSF6B HGNC:HGNC:44095|Ensembl:ENSG00000026036|Vega:OTTHUMG00000170363 +100533111 ZNF670-ZNF695 HGNC:HGNC:49200|Ensembl:ENSG00000135747|Vega:OTTHUMG00000187277 +100533177 KRTAP29-1 HGNC:HGNC:34211|Ensembl:ENSG00000212658|Vega:OTTHUMG00000133662 +100533178 PRORY HGNC:HGNC:38732|Ensembl:ENSG00000183146|Vega:OTTHUMG00000042036 +100533179 UBE2F-SCLY HGNC:HGNC:48339|Ensembl:ENSG00000258984|Vega:OTTHUMG00000170602 +100533181 FXYD6-FXYD2 HGNC:HGNC:39978|Ensembl:ENSG00000255245|Vega:OTTHUMG00000166496 +100533182 SEC24B-AS1 HGNC:HGNC:44003|Ensembl:ENSG00000247950 +100533183 ZNF664-RFLNA Ensembl:ENSG00000178882|Vega:OTTHUMG00000168609 +100533184 ARHGAP19-SLIT1 HGNC:HGNC:48348|Ensembl:ENSG00000269891|Vega:OTTHUMG00000184018 +100533195 FAM24B-CUZD1 - +100533464 PRH1-PRR4 Ensembl:ENSG00000275778|Vega:OTTHUMG00000186775 +100533467 BIVM-ERCC5 HGNC:HGNC:43690|Ensembl:ENSG00000270181|Vega:OTTHUMG00000184166 +100533483 DNAAF4-CCPG1 HGNC:HGNC:43019|Ensembl:ENSG00000261771 +100533496 TVP23C-CDRT4 HGNC:HGNC:42961|Ensembl:ENSG00000259024|Vega:OTTHUMG00000165004 +100533618 LOC100533618 - +100533619 TMPOP2 HGNC:HGNC:50860 +100533620 TUBBP7 HGNC:HGNC:42176 +100533621 LOC100533621 - +100533622 LOC100533622 - +100533624 SNX33P1 HGNC:HGNC:48590 +100533625 LOC100533625 - +100533626 LOC100533626 - +100533627 LOC100533627 - +100533628 LOC100533628 - +100533629 LOC100533629 - +100533630 LOC100533630 - +100533631 LOC100533631 - +100533632 LOC100533632 - +100533633 LOC100533633 - +100533634 LOC100533634 - +100533635 LOC100533635 - +100533636 LOC100533636 - +100533637 LOC100533637 - +100533638 LOC100533638 - +100533640 LOC100533640 - +100533641 LOC100533641 - +100533642 FNBP1P1 HGNC:HGNC:44528 +100533643 LOC100533643 - +100533644 LOC100533644 - +100533646 ZNF840P HGNC:HGNC:34344 +100533648 LOC100533648 - +100533649 LOC100533649 - +100533650 LOC100533650 - +100533651 LOC100533651 - +100533652 LOC100533652 - +100533653 LOC100533653 - +100533654 LOC100533654 - +100533655 LOC100533655 - +100533658 HSPA8P17 HGNC:HGNC:44932 +100533659 LOC100533659 - +100533660 EI24P5 HGNC:HGNC:44590 +100533661 SGO1P2 HGNC:HGNC:50777 +100533662 STK25P1 HGNC:HGNC:50361 +100533663 LOC100533663 - +100533664 PTCHD3P2 HGNC:HGNC:44946 +100533665 PTCHD3P3 HGNC:HGNC:44947 +100533666 SGO1P1 HGNC:HGNC:50776 +100533667 LOC100533667 - +100533668 KLF2P4 HGNC:HGNC:49283 +100533669 LOC100533669 - +100533670 LOC100533670 - +100533671 ADAM20P2 HGNC:HGNC:43901 +100533672 TRIM60P19 HGNC:HGNC:42010 +100533673 OSBPL9P6 HGNC:HGNC:48736 +100533674 NPAP1P4 HGNC:HGNC:45021 +100533675 NPAP1P6 HGNC:HGNC:45023 +100533676 PHACTR2P1 HGNC:HGNC:49488 +100533677 LOC100533677 - +100533678 LOC100533678 - +100533679 LOC100533679 - +100533682 MIPEPP1 HGNC:HGNC:39456 +100533695 RLIMP1 HGNC:HGNC:39682 +100533705 SLC9B1P5 HGNC:HGNC:43584 +100533706 LOC100533706 - +100533707 LOC100533707 - +100533708 LOC100533708 - +100533709 LOC100533709 - +100533710 LOC100533710 - +100533711 LOC100533711 - +100533712 LOC100533712 - +100533713 ELL2P3 HGNC:HGNC:39345 +100533714 DDX43P2 HGNC:HGNC:50781 +100533716 LOC100533716 - +100533717 BCAR1P1 HGNC:HGNC:51325 +100533718 BCAR1P2 HGNC:HGNC:51326 +100533719 ANKRD20A14P HGNC:HGNC:43605 +100533720 ANKRD20A15P HGNC:HGNC:43606 +100533721 PNPT1P2 HGNC:HGNC:44469 +100533722 LOC100533722 - +100533723 LOC100533723 - +100533725 ERVFRD-3 HGNC:HGNC:49792 +100533727 LOC100533727 - +100533728 LOC100533728 - +100533729 LOC100533729 - +100533730 LOC100533730 - +100533731 RLIMP2 HGNC:HGNC:39683 +100533732 LOC100533732 - +100533733 LOC100533733 - +100533734 LOC100533734 - +100533735 LOC100533735 - +100533736 LOC100533736 - +100533754 MARK3P3 HGNC:HGNC:50314 +100533755 LOC100533755 - +100533757 LOC100533757 - +100533787 LOC100533787 - +100533789 LRRC37A8P HGNC:HGNC:43793 +100533790 LRRC37A9P HGNC:HGNC:43813 +100533791 LRRC37A10P HGNC:HGNC:43814 +100533794 MARK2P15 HGNC:HGNC:45119 +100533795 MARK2P16 HGNC:HGNC:45171 +100533800 BMPR1APS2 HGNC:HGNC:21743 +100533814 LOC100533814 - +100533842 LOC100533842 - +100533843 LOC100533843 - +100533844 TARS2P1 HGNC:HGNC:43712 +100533845 LOC100533845 - +100533846 LOC100533846 - +100533847 TYW1P1 HGNC:HGNC:41905 +100533848 LOC100533848 - +100533849 MAPKAPK5P1 HGNC:HGNC:45246 +100533850 LOC100533850 - +100533851 ATP8A2P2 HGNC:HGNC:39663 +100533852 LOC100533852 - +100533853 LOC100533853 - +100533952 RBAK-RBAKDN HGNC:HGNC:42971|Ensembl:ENSG00000272968|Vega:OTTHUMG00000186010 +100533955 SENP3-EIF4A1 HGNC:HGNC:49182 +100533970 P2RX5-TAX1BP3 HGNC:HGNC:49191|Ensembl:ENSG00000257950|Vega:OTTHUMG00000169623 +100533975 SLMO2-ATP5E - +100533990 APOC4-APOC2 HGNC:HGNC:44426 +100533997 MAGEA10-MAGEA5 - +100534012 TNFAIP8L2-SCNM1 Ensembl:ENSG00000163156|Vega:OTTHUMG00000012258 +100534589 HOXA10-HOXA9 - +100534592 URGCP-MRPS24 HGNC:HGNC:49188|Ensembl:ENSG00000270617|Vega:OTTHUMG00000185136 +100534593 STX16-NPEPL1 HGNC:HGNC:41993|Ensembl:ENSG00000254995|Vega:OTTHUMG00000167390 +100534595 HNRNPUL2-BSCL2 HGNC:HGNC:49189|Ensembl:ENSG00000234857|Vega:OTTHUMG00000167772 +100534599 ISY1-RAB43 HGNC:HGNC:42969|Ensembl:ENSG00000261796|Vega:OTTHUMG00000177122 +100534611 TM4SF19-TCTEX1D2 HGNC:HGNC:49190 +100534612 C1QTNF3-AMACR HGNC:HGNC:49198|Ensembl:ENSG00000273294|Vega:OTTHUMG00000186337 +100551499 LINC00159 HGNC:HGNC:1285 +100568447 IGHV3OR16-14 HGNC:HGNC:5638|IMGT/GENE-DB:IGHV3/OR16-14 +100616100 ERVK-2 HGNC:HGNC:39001 +100616101 ERVK-10 HGNC:HGNC:39004 +100616102 ERVK-9 HGNC:HGNC:39005 +100616103 ERVK-21 HGNC:HGNC:39035 +100616104 ERVFH21-1 HGNC:HGNC:39047 +100616105 ERVE-4 HGNC:HGNC:39050 +100616106 ERVK3-4 HGNC:HGNC:39109 +100616107 ERVK3-6 HGNC:HGNC:39111 +100616108 ERVK3-8 HGNC:HGNC:39113 +100616109 MIR4464 HGNC:HGNC:41528|Ensembl:ENSG00000266760|miRBase:MI0016812 +100616110 MIR2681 HGNC:HGNC:41532|Ensembl:ENSG00000265164|miRBase:MI0012062 +100616111 MIR4455 HGNC:HGNC:41536|Ensembl:ENSG00000263458|miRBase:MI0016801 +100616112 MIR4793 HGNC:HGNC:41538|Ensembl:ENSG00000284575|miRBase:MI0017440 +100616113 MIR4680 HGNC:HGNC:41541|Ensembl:ENSG00000284482|miRBase:MI0017312 +100616114 MIR4668 HGNC:HGNC:41545|Ensembl:ENSG00000266315|miRBase:MI0017298 +100616115 MIR4469 HGNC:HGNC:41556|Ensembl:ENSG00000284062|miRBase:MI0016820 +100616116 MIR4648 HGNC:HGNC:41560|Ensembl:ENSG00000264357|miRBase:MI0017275 +100616117 MIR4653 HGNC:HGNC:41562|Ensembl:ENSG00000264425|miRBase:MI0017281 +100616118 MIR4486 HGNC:HGNC:41566|Ensembl:ENSG00000265210|miRBase:MI0016847 +100616119 MIR4697 HGNC:HGNC:41570|Ensembl:ENSG00000284020|miRBase:MI0017330 +100616120 MIR4695 HGNC:HGNC:41573|Ensembl:ENSG00000265606|miRBase:MI0017328 +100616121 MIR1268B HGNC:HGNC:41581|Ensembl:ENSG00000265561|miRBase:MI0016748 +100616122 MIR4523 HGNC:HGNC:41583|Ensembl:ENSG00000284162|miRBase:MI0016890 +100616123 MIR4436B1 HGNC:HGNC:41587|Ensembl:ENSG00000264979|miRBase:MI0017425 +100616124 MIR4647 HGNC:HGNC:41594|Ensembl:ENSG00000284427|miRBase:MI0017274 +100616125 MIR4731 HGNC:HGNC:41597|Ensembl:ENSG00000265110|miRBase:MI0017368 +100616126 MIR4686 HGNC:HGNC:41601|Ensembl:ENSG00000265258|miRBase:MI0017318 +100616127 MIR4448 HGNC:HGNC:41604|Ensembl:ENSG00000263932|miRBase:MI0016791 +100616128 MIR4679-1 HGNC:HGNC:41612|Ensembl:ENSG00000283664|miRBase:MI0017310 +100616129 MIR4445 HGNC:HGNC:41614|Ensembl:ENSG00000265956|miRBase:MI0016788 +100616130 MIR4526 HGNC:HGNC:41618|Ensembl:ENSG00000263527|miRBase:MI0016893 +100616131 MIR3689D1 HGNC:HGNC:41621|Ensembl:ENSG00000265848|miRBase:MI0016834 +100616132 MIR4728 HGNC:HGNC:41632|Ensembl:ENSG00000265178|miRBase:MI0017365 +100616133 MIR4699 HGNC:HGNC:41636|Ensembl:ENSG00000265227|miRBase:MI0017332 +100616134 MIR499B HGNC:HGNC:41640|Ensembl:ENSG00000283441|miRBase:MI0017396 +100616135 MIR4507 HGNC:HGNC:41642|Ensembl:ENSG00000264024|miRBase:MI0016871 +100616136 MIR4430 HGNC:HGNC:41646|Ensembl:ENSG00000283591|miRBase:MI0016769 +100616137 MIR4501 HGNC:HGNC:41650|Ensembl:ENSG00000283487|miRBase:MI0016864 +100616138 MIR4787 HGNC:HGNC:41653|Ensembl:ENSG00000272543|miRBase:MI0017434 +100616139 MIR4741 HGNC:HGNC:41661|Ensembl:ENSG00000284331|miRBase:MI0017379 +100616140 MIR4506 HGNC:HGNC:41663|Ensembl:ENSG00000265768|miRBase:MI0016869 +100616141 MIR4428 HGNC:HGNC:41667|Ensembl:ENSG00000266262|miRBase:MI0016767 +100616142 MIR4458 HGNC:HGNC:41674|Ensembl:ENSG00000284000|miRBase:MI0016804 +100616143 MIR4763 HGNC:HGNC:41677|Ensembl:ENSG00000284175|miRBase:MI0017404 +100616144 MIR548AN HGNC:HGNC:41681|Ensembl:ENSG00000263515|miRBase:MI0016907 +100616145 MIR1273G HGNC:HGNC:41684|Ensembl:ENSG00000265815|miRBase:MI0018003 +100616146 MIR4534 HGNC:HGNC:41692|Ensembl:ENSG00000284266|miRBase:MI0016901 +100616147 MIR4769 HGNC:HGNC:41694|Ensembl:ENSG00000263858|miRBase:MI0017410 +100616148 MIR4760 HGNC:HGNC:41698|Ensembl:ENSG00000263973|miRBase:MI0017401 +100616149 MIR4512 HGNC:HGNC:41701|Ensembl:ENSG00000266589|miRBase:MI0016878 +100616150 MIR4720 HGNC:HGNC:41705|Ensembl:ENSG00000284473|miRBase:MI0017355 +100616151 MIR4480 HGNC:HGNC:41716|Ensembl:ENSG00000263584|miRBase:MI0016841 +100616152 MIR4804 HGNC:HGNC:41720|Ensembl:ENSG00000263593|miRBase:MI0017452 +100616153 MIR4726 HGNC:HGNC:41722|Ensembl:ENSG00000273627|miRBase:MI0017363 +100616154 MIR4466 HGNC:HGNC:41726|Ensembl:ENSG00000271899|miRBase:MI0016817 +100616155 MIR4536-1 HGNC:HGNC:41730|Ensembl:ENSG00000283334|miRBase:MI0016906 +100616156 MIR1273F HGNC:HGNC:41733|Ensembl:ENSG00000264834|miRBase:MI0018002 +100616157 MIR4772 HGNC:HGNC:41741|Ensembl:ENSG00000264764|miRBase:MI0017414 +100616158 MIR4505 HGNC:HGNC:41743|Ensembl:ENSG00000264741|miRBase:MI0016868 +100616159 MIR4779 HGNC:HGNC:41747|Ensembl:ENSG00000265420|miRBase:MI0017423 +100616160 MIR4655 HGNC:HGNC:41754|Ensembl:ENSG00000265089|miRBase:MI0017283 +100616161 MIR4795 HGNC:HGNC:41757|Ensembl:ENSG00000264119|miRBase:MI0017442 +100616162 MIR4483 HGNC:HGNC:41761|Ensembl:ENSG00000283656|miRBase:MI0016844 +100616163 MIR4530 HGNC:HGNC:41764|Ensembl:ENSG00000266559|miRBase:MI0016897 +100616164 MIR4420 HGNC:HGNC:41772|Ensembl:ENSG00000264773|miRBase:MI0016757 +100616165 MIR4771-2 HGNC:HGNC:41774|Ensembl:ENSG00000266063|miRBase:MI0017413 +100616166 MIR4796 HGNC:HGNC:41779|Ensembl:ENSG00000264623|miRBase:MI0017443 +100616167 MIR4722 HGNC:HGNC:41782|Ensembl:ENSG00000284585|miRBase:MI0017357 +100616168 MIR4754 HGNC:HGNC:41786|Ensembl:ENSG00000266640|miRBase:MI0017394 +100616169 MIR378D2 HGNC:HGNC:41797|Ensembl:ENSG00000284288|miRBase:MI0003840 +100616170 MIR4739 HGNC:HGNC:41801|Ensembl:ENSG00000266665|miRBase:MI0017377 +100616171 MIR4752 HGNC:HGNC:41803|Ensembl:ENSG00000264703|miRBase:MI0017391 +100616172 MIR4719 HGNC:HGNC:41807|Ensembl:ENSG00000266426|miRBase:MI0017354 +100616173 MIR203B HGNC:HGNC:41811|Ensembl:ENSG00000283165|miRBase:MI0017343 +100616174 MIR4643 HGNC:HGNC:41814|Ensembl:ENSG00000263734|miRBase:MI0017270 +100616175 MIR4633 HGNC:HGNC:41822|Ensembl:ENSG00000264563|miRBase:MI0017260 +100616176 MIR4708 HGNC:HGNC:41824|Ensembl:ENSG00000266740|miRBase:MI0017341 +100616177 MIR4419A HGNC:HGNC:41828|Ensembl:ENSG00000266802|miRBase:MI0016755 +100616178 MIR4641 HGNC:HGNC:41835|Ensembl:ENSG00000266494|miRBase:MI0017268 +100616179 MIR4498 HGNC:HGNC:41838|Ensembl:ENSG00000266704|miRBase:MI0016860 +100616180 MIR4465 HGNC:HGNC:41842|Ensembl:ENSG00000264390|miRBase:MI0016816 +100616181 MIR4514 HGNC:HGNC:41845|Ensembl:ENSG00000265855|miRBase:MI0016880 +100616182 MIR4500 HGNC:HGNC:41853|Ensembl:ENSG00000266052|miRBase:MI0016863 +100616183 MIR4513 HGNC:HGNC:41855|Ensembl:ENSG00000264386|miRBase:MI0016879 +100616184 MIR4477A HGNC:HGNC:41859|Ensembl:ENSG00000276029|miRBase:MI0016829 +100616185 MIR371B HGNC:HGNC:41863|Ensembl:ENSG00000284568|miRBase:MI0017393 +100616186 MIR4490 HGNC:HGNC:41871|Ensembl:ENSG00000266703|miRBase:MI0016852 +100616187 MIR4783 HGNC:HGNC:41874|Ensembl:ENSG00000264075|miRBase:MI0017428 +100616188 MIR3972 HGNC:HGNC:41876|Ensembl:ENSG00000266634|miRBase:MI0016990 +100616189 MIR4421 HGNC:HGNC:41879|Ensembl:ENSG00000265538|miRBase:MI0016758 +100616190 MIR548O2 HGNC:HGNC:41882|Ensembl:ENSG00000275453|miRBase:MI0016746 +100616191 MIR548AJ1 HGNC:HGNC:41884|Ensembl:ENSG00000265669|miRBase:MI0016814 +100616192 MIR4679-2 HGNC:HGNC:41890|Ensembl:ENSG00000265375|miRBase:MI0017311 +100616193 MIR4453 HGNC:HGNC:41892|Ensembl:ENSG00000283792|miRBase:MI0016799 +100616194 MIR4477B HGNC:HGNC:41898|Ensembl:ENSG00000266017|miRBase:MI0016830 +100616195 MIR4718 HGNC:HGNC:41900|Ensembl:ENSG00000264733|miRBase:MI0017353 +100616196 MIR4525 HGNC:HGNC:41903|Ensembl:ENSG00000266107|miRBase:MI0016892 +100616197 ERVK-23 HGNC:HGNC:39037 +100616198 ERVW-6 HGNC:HGNC:39045 +100616199 ERVK3-7 HGNC:HGNC:39112 +100616200 ERVS71-2 HGNC:HGNC:41526 +100616201 MIR378D1 HGNC:HGNC:41550|Ensembl:ENSG00000263631|miRBase:MI0016749 +100616202 MIR4634 HGNC:HGNC:41559|Ensembl:ENSG00000266890|miRBase:MI0017261 +100616203 MIR4734 HGNC:HGNC:41572|Ensembl:ENSG00000275238|miRBase:MI0017371 +100616204 MIR4729 HGNC:HGNC:41585|Ensembl:ENSG00000263857|miRBase:MI0017366 +100616205 MIR4704 HGNC:HGNC:41602|Ensembl:ENSG00000263561|miRBase:MI0017337 +100616206 MIR4652 HGNC:HGNC:41615|Ensembl:ENSG00000265423|miRBase:MI0017280 +100616207 MIR4439 HGNC:HGNC:41622|Ensembl:ENSG00000263828|miRBase:MI0016782 +100616208 MIR4782 HGNC:HGNC:41635|Ensembl:ENSG00000265429|miRBase:MI0017427 +100616209 MIR4461 HGNC:HGNC:41656|Ensembl:ENSG00000263963|miRBase:MI0016807 +100616210 MIR4737 HGNC:HGNC:41669|Ensembl:ENSG00000264049|miRBase:MI0017374 +100616211 MIR4709 HGNC:HGNC:41690|Ensembl:ENSG00000283944|miRBase:MI0017342 +100616212 MIR3689F HGNC:HGNC:41702|Ensembl:ENSG00000266514|miRBase:MI0016837 +100616213 MIR4437 HGNC:HGNC:41715|Ensembl:ENSG00000266705|miRBase:MI0016778 +100616214 MIR4667 HGNC:HGNC:41723|Ensembl:ENSG00000263892|miRBase:MI0017297 +100616215 MIR548AL HGNC:HGNC:41736|Ensembl:ENSG00000264402|miRBase:MI0016851 +100616216 MIR4797 HGNC:HGNC:41758|Ensembl:ENSG00000265850|miRBase:MI0017444 +100616217 MIR1254-2 HGNC:HGNC:41770|Ensembl:ENSG00000264574|miRBase:MI0016747 +100616218 MIR3135B HGNC:HGNC:41783|Ensembl:ENSG00000263649|miRBase:MI0016809 +100616219 MIR4765 HGNC:HGNC:41791|Ensembl:ENSG00000265057|miRBase:MI0017406 +100616220 MIR4736 HGNC:HGNC:41804|Ensembl:ENSG00000264399|miRBase:MI0017373 +100616221 MIR4662A HGNC:HGNC:41826|Ensembl:ENSG00000283609|miRBase:MI0017290 +100616222 MIR4487 HGNC:HGNC:41851|Ensembl:ENSG00000264583|miRBase:MI0016848 +100616223 MIR4509-1 HGNC:HGNC:41860|Ensembl:ENSG00000276941|miRBase:MI0016873 +100616224 MIR4753 HGNC:HGNC:41527|Ensembl:ENSG00000263439|miRBase:MI0017392 +100616225 MIR4756 HGNC:HGNC:41529|Ensembl:ENSG00000265595|miRBase:MI0017397 +100616226 MIR4468 HGNC:HGNC:41533|Ensembl:ENSG00000284028|miRBase:MI0016819 +100616227 MIR4502 HGNC:HGNC:41534|Ensembl:ENSG00000265450|miRBase:MI0016865 +100616228 MIR4509-2 HGNC:HGNC:41537|Ensembl:ENSG00000266039|miRBase:MI0016874 +100616229 MIR4473 HGNC:HGNC:41540|Ensembl:ENSG00000263790|miRBase:MI0016825 +100616230 MIR4646 HGNC:HGNC:41543|Ensembl:ENSG00000266776|miRBase:MI0017273 +100616231 MIR4519 HGNC:HGNC:41544|Ensembl:ENSG00000265991|miRBase:MI0016885 +100616232 MIR4528 HGNC:HGNC:41547|Ensembl:ENSG00000263872|miRBase:MI0016895 +100616233 MIR4459 HGNC:HGNC:41551|Ensembl:ENSG00000265421|miRBase:MI0016805 +100616234 MIR4454 HGNC:HGNC:41553|Ensembl:ENSG00000283468|miRBase:MI0016800 +100616235 MIR4457 HGNC:HGNC:41554|Ensembl:ENSG00000263670|miRBase:MI0016803 +100616236 MIR4669 HGNC:HGNC:41558|Ensembl:ENSG00000263897|miRBase:MI0017300 +100616237 MIR4640 HGNC:HGNC:41561|Ensembl:ENSG00000284370|miRBase:MI0017267 +100616238 MIR3529 HGNC:HGNC:41564|Ensembl:ENSG00000283484|miRBase:MI0017351 +100616239 MIR4705 HGNC:HGNC:41567|Ensembl:ENSG00000264482|miRBase:MI0017338 +100616240 MIR4496 HGNC:HGNC:41569|Ensembl:ENSG00000284388|miRBase:MI0016858 +100616241 MIR4717 HGNC:HGNC:41571|Ensembl:ENSG00000264004|miRBase:MI0017352 +100616242 MIR4673 HGNC:HGNC:41574|Ensembl:ENSG00000263403|miRBase:MI0017304 +100616243 MIR4759 HGNC:HGNC:41575|Ensembl:ENSG00000266133|miRBase:MI0017400 +100616244 MIR3976 HGNC:HGNC:41578|Ensembl:ENSG00000272380|miRBase:MI0016994 +100616245 MIR4661 HGNC:HGNC:41582|Ensembl:ENSG00000266194|miRBase:MI0017289 +100616246 MIR4799 HGNC:HGNC:41584|Ensembl:ENSG00000264274|miRBase:MI0017446 +100616247 MIR151B HGNC:HGNC:41588|Ensembl:ENSG00000265154|miRBase:MI0003772 +100616248 MIR4724 HGNC:HGNC:41590|Ensembl:ENSG00000284424|miRBase:MI0017361 +100616249 MIR4768 HGNC:HGNC:41592|Ensembl:ENSG00000265465|miRBase:MI0017409 +100616250 MIR3960 HGNC:HGNC:41595|Ensembl:ENSG00000283863|miRBase:MI0016964 +100616251 MIR1587 HGNC:HGNC:41596|Ensembl:ENSG00000263972|miRBase:MI0016905 +100616252 MIR548AJ2 HGNC:HGNC:41600|Ensembl:ENSG00000221466|miRBase:MI0016815 +100616253 MIR4762 HGNC:HGNC:41603|Ensembl:ENSG00000264160|miRBase:MI0017403 +100616254 MIR548AH HGNC:HGNC:41605|Ensembl:ENSG00000283682|miRBase:MI0016796 +100616255 MIR4662B HGNC:HGNC:41607|Ensembl:ENSG00000263735|miRBase:MI0017293 +100616256 MIR4721 HGNC:HGNC:41609|Ensembl:ENSG00000283845|miRBase:MI0017356 +100616257 MIR3975 HGNC:HGNC:41613|Ensembl:ENSG00000283514|miRBase:MI0016993 +100616258 MIR4516 HGNC:HGNC:41617|Ensembl:ENSG00000265867|miRBase:MI0016882 +100616259 MIR378I HGNC:HGNC:41620|Ensembl:ENSG00000283829|miRBase:MI0016902 +100616260 MIR4663 HGNC:HGNC:41623|Ensembl:ENSG00000266324|miRBase:MI0017292 +100616261 MIR4504 HGNC:HGNC:41624|Ensembl:ENSG00000264712|miRBase:MI0016867 +100616262 MIR4701 HGNC:HGNC:41627|Ensembl:ENSG00000264201|miRBase:MI0017334 +100616263 MIR4485 HGNC:HGNC:41628|Ensembl:ENSG00000283813|miRBase:MI0016846 +100616264 MIR4527 HGNC:HGNC:41633|Ensembl:ENSG00000266582|miRBase:MI0016894 +100616265 MIR4433A HGNC:HGNC:41634|Ensembl:ENSG00000283222|miRBase:MI0016773 +100616266 MIR4733 HGNC:HGNC:41638|Ensembl:ENSG00000265444|miRBase:MI0017370 +100616267 MIR4776-1 HGNC:HGNC:41641|Ensembl:ENSG00000266354|miRBase:MI0017419 +100616268 MIR4472-1 HGNC:HGNC:41644|Ensembl:ENSG00000265247|miRBase:MI0016823 +100616269 MIR4639 HGNC:HGNC:41645|Ensembl:ENSG00000263712|miRBase:MI0017266 +100616270 MIR4651 HGNC:HGNC:41647|Ensembl:ENSG00000284334|miRBase:MI0017279 +100616271 MIR4637 HGNC:HGNC:41651|Ensembl:ENSG00000264792|miRBase:MI0017264 +100616272 MIR4422 HGNC:HGNC:41654|Ensembl:ENSG00000265822|miRBase:MI0016759 +100616273 MIR451B HGNC:HGNC:41655|Ensembl:ENSG00000283364|miRBase:MI0017360 +100616274 MIR4802 HGNC:HGNC:41658|Ensembl:ENSG00000263642|miRBase:MI0017450 +100616275 MIR4508 HGNC:HGNC:41659|Ensembl:ENSG00000265673|miRBase:MI0016872 +100616276 MIR4538 HGNC:HGNC:41664|Ensembl:ENSG00000263413|miRBase:MI0016909 +100616277 MIR4522 HGNC:HGNC:41668|Ensembl:ENSG00000263583|miRBase:MI0016889 +100616278 MIR4540 HGNC:HGNC:41670|Ensembl:ENSG00000264922|miRBase:MI0016911 +100616279 MIR3974 HGNC:HGNC:41672|Ensembl:ENSG00000283665|miRBase:MI0016992 +100616280 MIR4503 HGNC:HGNC:41675|Ensembl:ENSG00000266327|miRBase:MI0016866 +100616281 MIR4788 HGNC:HGNC:41676|Ensembl:ENSG00000284561|miRBase:MI0017435 +100616282 MIR4738 HGNC:HGNC:41679|Ensembl:ENSG00000283853|miRBase:MI0017376 +100616283 MIR4766 HGNC:HGNC:41680|Ensembl:ENSG00000266594|miRBase:MI0017407 +100616284 MIR4489 HGNC:HGNC:41685|Ensembl:ENSG00000265874|miRBase:MI0016850 +100616285 MIR4645 HGNC:HGNC:41689|Ensembl:ENSG00000266750|miRBase:MI0017272 +100616286 MIR4676 HGNC:HGNC:41691|Ensembl:ENSG00000266719|miRBase:MI0017307 +100616287 MIR4495 HGNC:HGNC:41693|Ensembl:ENSG00000265861|miRBase:MI0016857 +100616288 MIR4665 HGNC:HGNC:41696|Ensembl:ENSG00000263575|miRBase:MI0017295 +100616289 MIR4475 HGNC:HGNC:41697|Ensembl:ENSG00000266255|miRBase:MI0016827 +100616290 MIR4529 HGNC:HGNC:41703|Ensembl:ENSG00000264571|miRBase:MI0016896 +100616291 MIR4791 HGNC:HGNC:41704|Ensembl:ENSG00000271898|miRBase:MI0017438 +100616292 MIR4690 HGNC:HGNC:41707|Ensembl:ENSG00000266041|miRBase:MI0017323 +100616293 MIR4510 HGNC:HGNC:41708|Ensembl:ENSG00000265098|miRBase:MI0016876 +100616294 MIR4740 HGNC:HGNC:41711|Ensembl:ENSG00000266392|miRBase:MI0017378 +100616295 MIR4764 HGNC:HGNC:41714|Ensembl:ENSG00000266012|miRBase:MI0017405 +100616296 MIR4678 HGNC:HGNC:41717|Ensembl:ENSG00000283672|miRBase:MI0017309 +100616297 MIR3977 HGNC:HGNC:41721|Ensembl:ENSG00000283359|miRBase:MI0016995 +100616298 MIR4419B HGNC:HGNC:41724|Ensembl:ENSG00000265061|miRBase:MI0016861 +100616299 MIR4450 HGNC:HGNC:41725|Ensembl:ENSG00000263445|miRBase:MI0016795 +100616300 MIR4710 HGNC:HGNC:41727|Ensembl:ENSG00000265291|miRBase:MI0017344 +100616301 MIR4674 HGNC:HGNC:41729|Ensembl:ENSG00000265181|miRBase:MI0017305 +100616302 MIR548X2 HGNC:HGNC:41734|Ensembl:ENSG00000263581|miRBase:MI0016833 +100616303 MIR3688-2 HGNC:HGNC:41735|Ensembl:ENSG00000283379|miRBase:MI0017447 +100616304 MIR4499 HGNC:HGNC:41739|Ensembl:ENSG00000263978|miRBase:MI0016862 +100616305 MIR548AE1 HGNC:HGNC:41742|Ensembl:ENSG00000266808|miRBase:MI0016779 +100616306 MIR378H HGNC:HGNC:41744|Ensembl:ENSG00000263361|miRBase:MI0016808 +100616307 MIR4757 HGNC:HGNC:41746|Ensembl:ENSG00000266738|miRBase:MI0017398 +100616308 MIR4666A HGNC:HGNC:41750|Ensembl:ENSG00000266174|miRBase:MI0017296 +100616309 MIR4472-2 HGNC:HGNC:41752|Ensembl:ENSG00000264037|miRBase:MI0016824 +100616310 MIR4650-1 HGNC:HGNC:41755|Ensembl:ENSG00000266525|miRBase:MI0017277 +100616311 MIR3973 HGNC:HGNC:41756|Ensembl:ENSG00000263389|miRBase:MI0016991 +100616312 MIR4478 HGNC:HGNC:41759|Ensembl:ENSG00000266583|miRBase:MI0016831 +100616313 MIR4749 HGNC:HGNC:41760|Ensembl:ENSG00000265954|miRBase:MI0017388 +100616314 MIR4750 HGNC:HGNC:41765|Ensembl:ENSG00000284394|miRBase:MI0017389 +100616315 MIR4781 HGNC:HGNC:41769|Ensembl:ENSG00000283749|miRBase:MI0017426 +100616316 MIR4524A HGNC:HGNC:41771|Ensembl:ENSG00000283385|miRBase:MI0016891 +100616317 MIR4777 HGNC:HGNC:41773|Ensembl:ENSG00000263641|miRBase:MI0017421 +100616318 MIR4664 HGNC:HGNC:41777|Ensembl:ENSG00000265660|miRBase:MI0017294 +100616319 MIR4493 HGNC:HGNC:41778|Ensembl:ENSG00000265357|miRBase:MI0016855 +100616320 MIR4481 HGNC:HGNC:41781|Ensembl:ENSG00000283699|miRBase:MI0016842 +100616321 MIR378G HGNC:HGNC:41785|Ensembl:ENSG00000263526|miRBase:MI0016761 +100616322 MIR4682 HGNC:HGNC:41788|Ensembl:ENSG00000265370|miRBase:MI0017314 +100616323 MIR4482 HGNC:HGNC:41792|Ensembl:ENSG00000266852|miRBase:MI0016843 +100616324 MIR1245B HGNC:HGNC:41794|Ensembl:ENSG00000283238|miRBase:MI0017431 +100616325 MIR4460 HGNC:HGNC:41795|Ensembl:ENSG00000265691|miRBase:MI0016806 +100616326 MIR4636 HGNC:HGNC:41798|Ensembl:ENSG00000266415|miRBase:MI0017263 +100616327 MIR4484 HGNC:HGNC:41799|Ensembl:ENSG00000265092|miRBase:MI0016845 +100616328 MIR4424 HGNC:HGNC:41805|Ensembl:ENSG00000266417|miRBase:MI0016763 +100616329 MIR4700 HGNC:HGNC:41806|Ensembl:ENSG00000284143|miRBase:MI0017333 +100616330 MIR4491 HGNC:HGNC:41808|Ensembl:ENSG00000264032|miRBase:MI0016853 +100616331 MIR4650-2 HGNC:HGNC:41810|Ensembl:ENSG00000264494|miRBase:MI0017278 +100616332 MIR4716 HGNC:HGNC:41812|Ensembl:ENSG00000264210|miRBase:MI0017350 +100616333 MIR3689C HGNC:HGNC:41816|Ensembl:ENSG00000264744|miRBase:MI0016832 +100616334 MIR4790 HGNC:HGNC:41820|Ensembl:ENSG00000265180|miRBase:MI0017437 +100616335 MIR219B HGNC:HGNC:41823|Ensembl:ENSG00000283335|miRBase:MI0017299 +100616336 MIR548AB HGNC:HGNC:41825|Ensembl:ENSG00000265328|miRBase:MI0016752 +100616337 MIR4747 HGNC:HGNC:41827|Ensembl:ENSG00000263409|miRBase:MI0017386 +100616338 MIR4794 HGNC:HGNC:41829|Ensembl:ENSG00000264470|miRBase:MI0017441 +100616339 MIR548AE2 HGNC:HGNC:41831|Ensembl:ENSG00000265699|miRBase:MI0016780 +100616340 MIR4758 HGNC:HGNC:41836|Ensembl:ENSG00000284074|miRBase:MI0017399 +100616341 MIR4435-2 HGNC:HGNC:41837|Ensembl:ENSG00000266139|miRBase:MI0016777 +100616342 MIR4638 HGNC:HGNC:41841|Ensembl:ENSG00000264732|miRBase:MI0017265 +100616343 MIR4677 HGNC:HGNC:41844|Ensembl:ENSG00000265201|miRBase:MI0017308 +100616344 MIR3689D2 HGNC:HGNC:41846|Ensembl:ENSG00000264136|miRBase:MI0016835 +100616345 MIR4426 HGNC:HGNC:41848|Ensembl:ENSG00000283795|miRBase:MI0016765 +100616346 MIR4649 HGNC:HGNC:41852|Ensembl:ENSG00000284412|miRBase:MI0017276 +100616347 MIR548AI HGNC:HGNC:41854|Ensembl:ENSG00000265226|miRBase:MI0016813 +100616348 MIR4659A HGNC:HGNC:41857|Ensembl:ENSG00000266038|miRBase:MI0017287 +100616349 MIR4451 HGNC:HGNC:41858|Ensembl:ENSG00000266421|miRBase:MI0016797 +100616350 MIR4660 HGNC:HGNC:41861|Ensembl:ENSG00000263407|miRBase:MI0017288 +100616351 MIR4670 HGNC:HGNC:41862|Ensembl:ENSG00000264158|miRBase:MI0017301 +100616352 MIR4642 HGNC:HGNC:41865|Ensembl:ENSG00000266619|miRBase:MI0017269 +100616353 MIR4532 HGNC:HGNC:41869|Ensembl:ENSG00000263453|miRBase:MI0016899 +100616354 MIR550A3 HGNC:HGNC:41870|Ensembl:ENSG00000212024|miRBase:MI0003762 +100616355 MIR4531 HGNC:HGNC:41872|Ensembl:ENSG00000283673|miRBase:MI0016898 +100616356 MIR4774 HGNC:HGNC:41873|Ensembl:ENSG00000265694|miRBase:MI0017417 +100616357 MIR3591 HGNC:HGNC:41875|Ensembl:ENSG00000207778|miRBase:MI0017383 +100616358 MIR4800 HGNC:HGNC:41877|Ensembl:ENSG00000284276|miRBase:MI0017448 +100616359 MIR4730 HGNC:HGNC:41880|Ensembl:ENSG00000264961|miRBase:MI0017367 +100616360 MIR2467 HGNC:HGNC:41881|Ensembl:ENSG00000264292|miRBase:MI0017432 +100616361 MIR4775 HGNC:HGNC:41885|Ensembl:ENSG00000284079|miRBase:MI0017418 +100616362 MIR4533 HGNC:HGNC:41886|Ensembl:ENSG00000266140|miRBase:MI0016900 +100616363 MIR4735 HGNC:HGNC:41888|Ensembl:ENSG00000265986|miRBase:MI0017372 +100616364 MIR4785 HGNC:HGNC:41889|Ensembl:ENSG00000283734|miRBase:MI0017430 +100616365 MIR4425 HGNC:HGNC:41891|Ensembl:ENSG00000264371|miRBase:MI0016764 +100616366 MIR4743 HGNC:HGNC:41894|Ensembl:ENSG00000266276|miRBase:MI0017381 +100616367 MIR4467 HGNC:HGNC:41896|Ensembl:ENSG00000284596|miRBase:MI0016818 +100616368 MIR4688 HGNC:HGNC:41897|Ensembl:ENSG00000264102|miRBase:MI0017321 +100616369 MIR4713 HGNC:HGNC:41899|Ensembl:ENSG00000266593|miRBase:MI0017347 +100616370 MIR4771-1 HGNC:HGNC:41901|Ensembl:ENSG00000264793|miRBase:MI0017412 +100616371 MIR4746 HGNC:HGNC:41904|Ensembl:ENSG00000266437|miRBase:MI0017385 +100616372 MIR4659B HGNC:HGNC:41530|Ensembl:ENSG00000283386|miRBase:MI0017291 +100616373 MIR4770 HGNC:HGNC:41542|Ensembl:ENSG00000265284|miRBase:MI0017411 +100616374 MIR4539 HGNC:HGNC:41546|Ensembl:ENSG00000265612|miRBase:MI0016910 +100616375 MIR4438 HGNC:HGNC:41555|Ensembl:ENSG00000265734|miRBase:MI0016781 +100616376 MIR4492 HGNC:HGNC:41563|Ensembl:ENSG00000264211|miRBase:MI0016854 +100616377 MIR4803 HGNC:HGNC:41568|Ensembl:ENSG00000264099|miRBase:MI0017451 +100616378 MIR4784 HGNC:HGNC:41580|Ensembl:ENSG00000284149|miRBase:MI0017429 +100616379 MIR4511 HGNC:HGNC:41589|Ensembl:ENSG00000264737|miRBase:MI0016877 +100616380 MIR4671 HGNC:HGNC:41598|Ensembl:ENSG00000264377|miRBase:MI0017302 +100616381 MIR4456 HGNC:HGNC:41606|Ensembl:ENSG00000264233|miRBase:MI0016802 +100616382 MIR4509-3 HGNC:HGNC:41610|Ensembl:ENSG00000263964|miRBase:MI0016875 +100616383 MIR4675 HGNC:HGNC:41619|Ensembl:ENSG00000265372|miRBase:MI0017306 +100616384 MIR548AC HGNC:HGNC:41626|Ensembl:ENSG00000264419|miRBase:MI0016762 +100616385 MIR4732 HGNC:HGNC:41639|Ensembl:ENSG00000284085|miRBase:MI0017369 +100616386 MIR4654 HGNC:HGNC:41643|Ensembl:ENSG00000266144|miRBase:MI0017282 +100616387 MIR3064 HGNC:HGNC:41652|Ensembl:ENSG00000284564|miRBase:MI0017375 +100616388 MIR4723 HGNC:HGNC:41660|Ensembl:ENSG00000284532|miRBase:MI0017359 +100616389 MIR4463 HGNC:HGNC:41665|Ensembl:ENSG00000263533|miRBase:MI0016811 +100616390 MIR4427 HGNC:HGNC:41678|Ensembl:ENSG00000265744|miRBase:MI0016766 +100616391 MIR4684 HGNC:HGNC:41695|Ensembl:ENSG00000265422|miRBase:MI0017316 +100616392 MIR4773-1 HGNC:HGNC:41699|Ensembl:ENSG00000264684|miRBase:MI0017415 +100616393 MIR4657 HGNC:HGNC:41706|Ensembl:ENSG00000284261|miRBase:MI0017285 +100616394 MIR4444-1 HGNC:HGNC:41710|Ensembl:ENSG00000284252|miRBase:MI0016787 +100616395 MIR4789 HGNC:HGNC:41719|Ensembl:ENSG00000264974|miRBase:MI0017436 +100616396 MIR4712 HGNC:HGNC:41732|Ensembl:ENSG00000284284|miRBase:MI0017346 +100616397 MIR4440 HGNC:HGNC:41740|Ensembl:ENSG00000266109|miRBase:MI0016783 +100616398 MIR4681 HGNC:HGNC:41753|Ensembl:ENSG00000265719|miRBase:MI0017313 +100616399 MIR4436A HGNC:HGNC:41762|Ensembl:ENSG00000265510|miRBase:MI0016776 +100616400 MIR3198-2 HGNC:HGNC:41766|Ensembl:ENSG00000283803|miRBase:MI0017335 +100616401 MIR4520-1 HGNC:HGNC:41775|Ensembl:ENSG00000264468|miRBase:MI0016886 +100616402 MIR4696 HGNC:HGNC:41780|Ensembl:ENSG00000265902|miRBase:MI0017329 +100616403 MIR4691 HGNC:HGNC:41796|Ensembl:ENSG00000284435|miRBase:MI0017324 +100616404 MIR4515 HGNC:HGNC:41800|Ensembl:ENSG00000263643|miRBase:MI0016881 +100616405 MIR4518 HGNC:HGNC:41809|Ensembl:ENSG00000266305|miRBase:MI0016884 +100616406 MIR4521 HGNC:HGNC:41813|Ensembl:ENSG00000283160|miRBase:MI0016887 +100616407 MIR4443 HGNC:HGNC:41830|Ensembl:ENSG00000265483|miRBase:MI0016786 +100616408 MIR5047 HGNC:HGNC:41834|Ensembl:ENSG00000284368|miRBase:MI0017932 +100616409 MIR4711 HGNC:HGNC:41847|Ensembl:ENSG00000266150|miRBase:MI0017345 +100616410 MIR4692 HGNC:HGNC:41856|Ensembl:ENSG00000265064|miRBase:MI0017325 +100616411 ERVK-16 HGNC:HGNC:39023 +100616412 ERVK3-5 HGNC:HGNC:39110 +100616413 MIR4462 HGNC:HGNC:41549|Ensembl:ENSG00000263926|miRBase:MI0016810 +100616414 MIR4761 HGNC:HGNC:41591|Ensembl:ENSG00000284031|miRBase:MI0017402 +100616415 MIR4535 HGNC:HGNC:41629|Ensembl:ENSG00000266887|miRBase:MI0016903 +100616416 MIR4727 HGNC:HGNC:41709|Ensembl:ENSG00000274054|miRBase:MI0017364 +100616417 MIR4786 HGNC:HGNC:41751|Ensembl:ENSG00000264279|miRBase:MI0017433 +100616418 MIR4773-2 HGNC:HGNC:41790|Ensembl:ENSG00000283569|miRBase:MI0017416 +100616419 MIR4434 HGNC:HGNC:41832|Ensembl:ENSG00000283204|miRBase:MI0016774 +100616420 MIR4744 HGNC:HGNC:41866|Ensembl:ENSG00000263849|miRBase:MI0017382 +100616421 MIR4689 HGNC:HGNC:41895|Ensembl:ENSG00000264101|miRBase:MI0017322 +100616422 MIR4537 HGNC:HGNC:41682|Ensembl:ENSG00000264781|miRBase:MI0016908 +100616423 MIR4703 HGNC:HGNC:41817|Ensembl:ENSG00000266611|miRBase:MI0017336 +100616424 MIR4707 HGNC:HGNC:41531|Ensembl:ENSG00000284118|miRBase:MI0017340 +100616425 MIR4748 HGNC:HGNC:41557|Ensembl:ENSG00000265879|miRBase:MI0017387 +100616426 MIR4694 HGNC:HGNC:41586|Ensembl:ENSG00000264309|miRBase:MI0017327 +100616427 MIR5096 HGNC:HGNC:41611|Ensembl:ENSG00000266270|miRBase:MI0018004 +100616428 MIR548AM HGNC:HGNC:41637|Ensembl:ENSG00000265144|miRBase:MI0016904 +100616429 MIR4672 HGNC:HGNC:41662|Ensembl:ENSG00000263979|miRBase:MI0017303 +100616430 MIR4644 HGNC:HGNC:41687|Ensembl:ENSG00000266245|miRBase:MI0017271 +100616431 MIR4431 HGNC:HGNC:41738|Ensembl:ENSG00000264975|miRBase:MI0016771 +100616432 MIR4714 HGNC:HGNC:41763|Ensembl:ENSG00000264480|miRBase:MI0017348 +100616433 MIR4418 HGNC:HGNC:41789|Ensembl:ENSG00000266564|miRBase:MI0016754 +100616434 MIR4755 HGNC:HGNC:41815|Ensembl:ENSG00000264616|miRBase:MI0017395 +100616435 MIR4801 HGNC:HGNC:41840|Ensembl:ENSG00000264319|miRBase:MI0017449 +100616436 MIR4449 MIM:614627|HGNC:HGNC:41864|Ensembl:ENSG00000264585|miRBase:MI0016792 +100616437 MIR1343 HGNC:HGNC:41902|Ensembl:ENSG00000251862|miRBase:MI0017320 +100616438 MIR4632 HGNC:HGNC:41593|Ensembl:ENSG00000263676|miRBase:MI0017259 +100616439 MIR4658 HGNC:HGNC:41673|Ensembl:ENSG00000284518|miRBase:MI0017286 +100616440 MIR548AG2 HGNC:HGNC:41745|Ensembl:ENSG00000265617|miRBase:MI0016794 +100616441 MIR4474 HGNC:HGNC:41821|Ensembl:ENSG00000264941|miRBase:MI0016826 +100616442 ERVK-12 HGNC:HGNC:39007 +100616443 ERVK-15 HGNC:HGNC:39022 +100616444 ERVK-20 HGNC:HGNC:39031 +100616445 ERVK-22 HGNC:HGNC:39036 +100616446 ERVH-1 HGNC:HGNC:39053 +100616447 MIR4780 HGNC:HGNC:41552|Ensembl:ENSG00000265003|miRBase:MI0017424 +100616448 MIR4792 HGNC:HGNC:41577|Ensembl:ENSG00000265028|miRBase:MI0017439 +100616449 MIR4725 HGNC:HGNC:41608|Ensembl:ENSG00000265976|miRBase:MI0017362 +100616450 MIR548AG1 HGNC:HGNC:41625|Ensembl:ENSG00000265829|miRBase:MI0016793 +100616451 MIR4471 HGNC:HGNC:41657|Ensembl:ENSG00000265599|miRBase:MI0016822 +100616452 MIR2682 HGNC:HGNC:41688|Ensembl:ENSG00000284247|miRBase:MI0012063 +100616453 MIR4687 HGNC:HGNC:41712|Ensembl:ENSG00000284525|miRBase:MI0017319 +100616454 MIR4497 HGNC:HGNC:41737|Ensembl:ENSG00000263510|miRBase:MI0016859 +100616455 MIR548H5 HGNC:HGNC:41768|Ensembl:ENSG00000266807|miRBase:MI0016751 +100616456 MIR4476 HGNC:HGNC:41793|Ensembl:ENSG00000265368|miRBase:MI0016828 +100616457 MIR4693 HGNC:HGNC:41818|Ensembl:ENSG00000264200|miRBase:MI0017326 +100616458 MIR5095 HGNC:HGNC:41849|Ensembl:ENSG00000266188|miRBase:MI0018001 +100616459 MIR4745 HGNC:HGNC:41868|Ensembl:ENSG00000284361|miRBase:MI0017384 +100616460 MIR3689E HGNC:HGNC:41887|Ensembl:ENSG00000266827|miRBase:MI0016836 +100616461 ERVH-2 HGNC:HGNC:39054 +100616462 ERVK3-3 HGNC:HGNC:39108 +100616463 MIR4452 HGNC:HGNC:41539|Ensembl:ENSG00000266515|miRBase:MI0016798 +100616464 MIR4778 HGNC:HGNC:41648|Ensembl:ENSG00000264525|miRBase:MI0017422 +100616465 MIR4656 HGNC:HGNC:41749|Ensembl:ENSG00000264474|miRBase:MI0017284 +100616466 MIR4520-2 HGNC:HGNC:41839|Ensembl:ENSG00000283301|miRBase:MI0017358 +100616467 MIR4767 HGNC:HGNC:41548|Ensembl:ENSG00000264268|miRBase:MI0017408 +100616468 MIR4742 HGNC:HGNC:41565|Ensembl:ENSG00000266618|miRBase:MI0017380 +100616469 MIR4429 HGNC:HGNC:41579|Ensembl:ENSG00000264010|miRBase:MI0016768 +100616470 MIR4488 HGNC:HGNC:41599|Ensembl:ENSG00000266006|miRBase:MI0016849 +100616471 MIR4798 HGNC:HGNC:41616|Ensembl:ENSG00000264658|miRBase:MI0017445 +100616472 MIR4776-2 HGNC:HGNC:41631|Ensembl:ENSG00000283637|miRBase:MI0017420 +100616473 MIR4432 HGNC:HGNC:41649|Ensembl:ENSG00000266078|miRBase:MI0016772 +100616474 MIR4715 HGNC:HGNC:41666|Ensembl:ENSG00000266517|miRBase:MI0017349 +100616475 MIR548AD HGNC:HGNC:41683|Ensembl:ENSG00000265301|miRBase:MI0016770 +100616476 MIR4446 HGNC:HGNC:41700|Ensembl:ENSG00000265253|miRBase:MI0016789 +100616477 MIR4442 HGNC:HGNC:41718|Ensembl:ENSG00000283971|miRBase:MI0016785 +100616478 MIR4494 HGNC:HGNC:41731|Ensembl:ENSG00000264906|miRBase:MI0016856 +100616479 MIR4635 HGNC:HGNC:41748|Ensembl:ENSG00000263834|miRBase:MI0017262 +100616480 MIR4479 HGNC:HGNC:41767|Ensembl:ENSG00000266507|miRBase:MI0016838 +100616481 MIR4423 HGNC:HGNC:41784|Ensembl:ENSG00000266110|miRBase:MI0016760 +100616482 MIR4685 HGNC:HGNC:41802|Ensembl:ENSG00000264610|miRBase:MI0017317 +100616483 MIR4751 HGNC:HGNC:41819|Ensembl:ENSG00000283842|miRBase:MI0017390 +100616484 MIR4470 HGNC:HGNC:41833|Ensembl:ENSG00000264408|miRBase:MI0016821 +100616485 MIR4447 HGNC:HGNC:41850|Ensembl:ENSG00000265433|miRBase:MI0016790 +100616486 MIR4698 HGNC:HGNC:41867|Ensembl:ENSG00000263838|miRBase:MI0017331 +100616487 MIR4517 HGNC:HGNC:41878|Ensembl:ENSG00000284541|miRBase:MI0016883 +100616488 MIR548AK HGNC:HGNC:41893|Ensembl:ENSG00000265653|miRBase:MI0016840 +100616489 MIR4417 HGNC:HGNC:41535|Ensembl:ENSG00000264341|miRBase:MI0016753 +100616490 MIR4706 HGNC:HGNC:41576|Ensembl:ENSG00000266531|miRBase:MI0017339 +100616491 MIR3978 HGNC:HGNC:41630|Ensembl:ENSG00000265584|miRBase:MI0016996 +100616492 MIR378F HGNC:HGNC:41686|Ensembl:ENSG00000264926|miRBase:MI0016756 +100616493 MIR4441 HGNC:HGNC:41728|Ensembl:ENSG00000264810|miRBase:MI0016784 +100616494 MIR1269B HGNC:HGNC:41787|Ensembl:ENSG00000265503|miRBase:MI0016888 +100616495 MIR2392 HGNC:HGNC:41843|Ensembl:ENSG00000266461|miRBase:MI0016870 +100616496 ERVW-4 HGNC:HGNC:39043 +100616497 ERV9-1 HGNC:HGNC:39060 +100616498 MIR378E HGNC:HGNC:41671|Ensembl:ENSG00000263831|miRBase:MI0016750 +100616499 MIR4435-1 HGNC:HGNC:41713|Ensembl:ENSG00000265507|miRBase:MI0016775 +100616500 MIR4683 HGNC:HGNC:41883|Ensembl:ENSG00000284265|miRBase:MI0017315 +100616530 C8orf37-AS1 HGNC:HGNC:50444|Ensembl:ENSG00000253773 +100616668 TPTE2P5 HGNC:HGNC:42356 +100628307 DIO2-AS1 HGNC:HGNC:44153|Ensembl:ENSG00000258766 +100628315 DNM3OS HGNC:HGNC:41228|Ensembl:ENSG00000230630 +100628560 MIR3155B HGNC:HGNC:50003|Ensembl:ENSG00000283634|miRBase:MI0016839 +100629121 LOC100629121 - +100630918 PARTICL MIM:616350|HGNC:HGNC:50886 +100630919 LOC100630919 - +100630920 RPL10P18 HGNC:HGNC:52349 +100630923 LOC100630923 - +100631239 KRT18P67 HGNC:HGNC:48894 +100631242 LOC100631242 - +100631243 LOC100631243 - +100631247 GRAMD4P8 HGNC:HGNC:49143 +100631248 GRAMD4P3 HGNC:HGNC:49138 +100631249 GRAMD4P5 HGNC:HGNC:49140 +100631250 GRAMD4P6 HGNC:HGNC:49141 +100631251 GRAMD4P7 HGNC:HGNC:49142 +100631252 GRAMD4P1 HGNC:HGNC:39653 +100631253 TBC1D3P4 HGNC:HGNC:32409 +100631254 CSPG4P11 HGNC:HGNC:48363 +100631255 LOC100631255 - +100631258 LOC100631258 - +100631260 MARK2P13 HGNC:HGNC:39804 +100631261 MARK2P14 HGNC:HGNC:44495 +100631265 LOC100631265 - +100631266 LOC100631266 - +100631267 LOC100631267 - +100631268 LOC100631268 - +100631269 SLC10A5P1 HGNC:HGNC:48930 +100631378 LOC100631378 Ensembl:ENSG00000225868 +100631380 LOC100631380 - +100631381 PPP6R2P1 HGNC:HGNC:39605 +100631382 ZFAND6P1 HGNC:HGNC:42978 +100631383 FAM47E-STBD1 HGNC:HGNC:44667|Ensembl:ENSG00000272414|Vega:OTTHUMG00000160966 +100642175 SPRY4-IT1 HGNC:HGNC:42394|Ensembl:ENSG00000281881 +100642176 LINC00266-4P HGNC:HGNC:38800 +100652730 LINC00659 HGNC:HGNC:44316 +100652736 LINC01311 HGNC:HGNC:50503 +100652739 RAET1E-AS1 HGNC:HGNC:48994|Ensembl:ENSG00000223701|Ensembl:ENSG00000268592 +100652740 PYCARD-AS1 HGNC:HGNC:45036|Ensembl:ENSG00000261359 +100652743 LOC100652743 - +100652748 TIMM23B HGNC:HGNC:23581|Ensembl:ENSG00000204152|Vega:OTTHUMG00000018213 +100652749 SPATA8-AS1 HGNC:HGNC:48627|Ensembl:ENSG00000259282 +100652758 LOC100652758 - +100652759 PRICKLE2-AS1 HGNC:HGNC:40916|Ensembl:ENSG00000241111 +100652768 LOC100652768 - +100652770 DSG2-AS1 HGNC:HGNC:51311|Ensembl:ENSG00000264859 +100652772 NNT-AS1 HGNC:HGNC:49005 +100652777 LOC100652777 - +100652781 SNX29P1 HGNC:HGNC:31913 +100652791 GS1-24F4.2 Ensembl:ENSG00000245857 +100652792 LOC100652792 - +100652794 LOC100652794 - +100652796 BOLA2P1 HGNC:HGNC:51437 +100652801 NXT1P1 HGNC:HGNC:39708 +100652813 LOC100652813 - +100652824 KIAA2012 HGNC:HGNC:51250|Ensembl:ENSG00000182329|Vega:OTTHUMG00000154580 +100652831 NANOGNBP3 HGNC:HGNC:42160 +100652833 LOC100652833 - +100652840 LOC100652840 - +100652846 CACNA1C-AS1 HGNC:HGNC:40119|Ensembl:ENSG00000246627 +100652853 LINC01023 HGNC:HGNC:49004|Ensembl:ENSG00000272523 +100652856 LINC00408 HGNC:HGNC:42740 +100652857 TMCO5B HGNC:HGNC:34243 +100652865 LINC00539 HGNC:HGNC:43672 +100652871 LOC100652871 - +100652883 ALOX15P1 HGNC:HGNC:13742 +100652885 SIRPB3P HGNC:HGNC:49209 +100652897 LOC100652897 - +100652899 ANP32BP3 HGNC:HGNC:44089 +100652901 LOC100652901 - +100652908 LOC100652908 - +100652909 LINC00904 HGNC:HGNC:44325|Ensembl:ENSG00000271649 +100652911 LINC01838 HGNC:HGNC:52654|Ensembl:ENSG00000269037 +100652918 GAPDHP75 HGNC:HGNC:50648 +100652929 LINC02078 HGNC:HGNC:52926|Ensembl:ENSG00000267719 +100652931 LOC100652931 - +100652939 MTND2P28 HGNC:HGNC:42129 +100652955 LOC100652955 - +100652960 LOC100652960 - +100652967 LOC100652967 - +100652974 SOD1P2 HGNC:HGNC:45135 +100652976 LOC100652976 - +100652988 LINC00702 HGNC:HGNC:44676 +100652997 LINC00706 HGNC:HGNC:44690|Ensembl:ENSG00000281186 +100652999 LOC100652999 Ensembl:ENSG00000257550 +100653049 LOC100653049 - +100653053 TAS2R68P HGNC:HGNC:43905 +100653061 LOC100653061 - +100653133 LOC100653133 - +100653233 LOC100653233 Ensembl:ENSG00000260653 +100653365 BED MIM:300843 +100653366 PSC MIM:613806 +100653367 OFC13 MIM:613857 +100653368 SCA32 MIM:613909|HGNC:HGNC:37475 +100653369 APMR3 MIM:613930 +100653370 MYP19 MIM:613969 +100653371 CPVT3 MIM:614021 +100653372 SRXX3 MIM:300833 +100653373 KONDS MIM:606242 +100653374 DEL17P13.1 MIM:613776 +100653375 ADIPQTL5 MIM:613836 +100653377 SPGF2 MIM:108420 +100653378 SRXX2 MIM:278850 +100653379 MYMY4 MIM:300845 +100653380 DEL7Q11.23 MIM:613729 +100653381 GEFSP8 MIM:613828 +100653382 DEL13Q14 MIM:613884 +100653383 PSMNSW MIM:613938 +100653384 IGAN2 MIM:613944 +100653385 DEL3PTERP25 MIM:613792 +100653390 DFNB81 MIM:614129|HGNC:HGNC:35420 +100653393 CACD3 MIM:613144 +100653395 LOC100653395 - +100653396 YPEL5P3 HGNC:HGNC:50557 +100653423 BANF1P4 HGNC:HGNC:43884 +100653489 MTND4P14 HGNC:HGNC:42201 +100653515 CEP295NL HGNC:HGNC:44659|Ensembl:ENSG00000178404|Vega:OTTHUMG00000177628 +100682260 HPPD MIM:614187 +100682325 NDNC9 MIM:614149 +100682326 MYP20 MIM:614166 +100682395 LNCR5 MIM:614210 +100689013 MRT17 MIM:614207|HGNC:HGNC:39145 +100689014 MRT16 MIM:614208 +100689073 ARHGAP22-IT1 HGNC:HGNC:42944 +100689074 POU6F2-AS2 HGNC:HGNC:21887 +100689211 HYSP3 MIM:146450 +100689212 PBC5 MIM:614221 +100689213 GFND1 MIM:137950 +100689214 HYSP4 MIM:300856 +100689215 PBC4 MIM:614220 +100689216 NRCLP6 MIM:614223 +100689229 H3F3AP3 HGNC:HGNC:42873 +100689296 CNN2P11 HGNC:HGNC:39536 +100689490 HNFJ3 MIM:614227 +100689491 DEL8Q21.11 MIM:614230 +100736250 HYPT9 MIM:614237 +100736251 HYP10 MIM:614238 +100736408 LOC100736408 - +100736411 ASH2LP3 HGNC:HGNC:53060 +100736412 LOC100736412 - +100739996 MRXS17 MIM:300858 +100750225 PCAT1 MIM:616043|HGNC:HGNC:43022|Ensembl:ENSG00000253438 +100750238 EJM9 MIM:614280 +100750245 SNAPC5P1 HGNC:HGNC:38667 +100750246 HIF1A-AS1 MIM:614528|HGNC:HGNC:43014|Ensembl:ENSG00000258777 +100750247 HIF1A-AS2 MIM:614529|HGNC:HGNC:43015 +100750325 RCAN3AS HGNC:HGNC:39009 +100750326 HTT-AS HGNC:HGNC:37118 +100750328 ANIB11 MIM:614252 +100750329 TET18P MIM:614290 +100775104 KLHL7-AS1 HGNC:HGNC:43431|Ensembl:ENSG00000230658 +100775105 ERVK-18 HGNC:HGNC:39025 +100775107 RBM5-AS1 HGNC:HGNC:48871|Ensembl:ENSG00000281691 +100820631 MLSM7 MIM:252270 +100820632 DEL15Q25 MIM:614294 +100820633 DEL2Q23.1 MIM:156200 +100820709 LINC00501 HGNC:HGNC:43439|Ensembl:ENSG00000203645 +100820732 LSM1P1 HGNC:HGNC:49776 +100820733 LOC100820733 - +100820734 LOC100820734 - +100820735 HIST1H2BPS3 HGNC:HGNC:42633 +100820741 RBBP4P6 HGNC:HGNC:42373 +100820757 VUR4 MIM:614317 +100820758 CCCSX MIM:300864 +100820759 SPGFX2 MIM:309120 +100820760 VUR5 MIM:614318 +100820761 MRXSCS MIM:300861 +100820762 CPBHM MIM:300863 +100820763 VUR6 MIM:614319 +100820829 MYZAP MIM:614071|HGNC:HGNC:43444|Ensembl:ENSG00000137878|Ensembl:ENSG00000263155|Vega:OTTHUMG00000132453|Vega:OTTHUMG00000176411 +100846978 LINC00506 HGNC:HGNC:43557|Ensembl:ENSG00000281392 +100846991 MIR5197 HGNC:HGNC:43450|Ensembl:ENSG00000266478|miRBase:MI0018176 +100846992 MIR548AW HGNC:HGNC:43454|Ensembl:ENSG00000263816|miRBase:MI0019283 +100846993 MIR5009 HGNC:HGNC:43458|Ensembl:ENSG00000264796|miRBase:MI0017877 +100846994 MIR3670-2 HGNC:HGNC:43460|Ensembl:ENSG00000264722|miRBase:MI0019112 +100846995 MIR5000 HGNC:HGNC:43464|Ensembl:ENSG00000263909|miRBase:MI0017866 +100846996 MIR5007 HGNC:HGNC:43468|Ensembl:ENSG00000264387|miRBase:MI0017874 +100846997 MIR5583-2 HGNC:HGNC:43471|Ensembl:ENSG00000283645|miRBase:MI0019140 +100846998 MIR5689 HGNC:HGNC:43479|Ensembl:ENSG00000263705|miRBase:MI0019294 +100846999 MIR4444-2 HGNC:HGNC:43481|Ensembl:ENSG00000266780|miRBase:MI0019111 +100847000 MIR5579 HGNC:HGNC:43485|Ensembl:ENSG00000266570|miRBase:MI0019133 +100847001 MIR5680 HGNC:HGNC:43492|Ensembl:ENSG00000266756|miRBase:MI0019280 +100847002 MIR5011 HGNC:HGNC:43496|Ensembl:ENSG00000263354|miRBase:MI0017879 +100847003 MIR5693 HGNC:HGNC:43499|Ensembl:ENSG00000266072|miRBase:MI0019300 +100847004 MIR5188 HGNC:HGNC:43502|Ensembl:ENSG00000265345|miRBase:MI0018167 +100847005 MIR5701-2 HGNC:HGNC:43510|Ensembl:ENSG00000277841|miRBase:MI0019593 +100847006 MIR5571 HGNC:HGNC:43513|Ensembl:ENSG00000264824|miRBase:MI0019115 +100847007 MIR5696 HGNC:HGNC:43516|Ensembl:ENSG00000264857|miRBase:MI0019303 +100847008 MIR4524B HGNC:HGNC:43520|Ensembl:ENSG00000265331|miRBase:MI0019114 +100847009 MIR1295B HGNC:HGNC:43524|Ensembl:ENSG00000283598|miRBase:MI0019146 +100847010 MIR5581 HGNC:HGNC:43527|Ensembl:ENSG00000263675|miRBase:MI0019136 +100847012 MIR5004 HGNC:HGNC:43532|Ensembl:ENSG00000284256|miRBase:MI0017870 +100847013 MIR5692B HGNC:HGNC:43535|Ensembl:ENSG00000264580|miRBase:MI0019311 +100847014 MIR5100 HGNC:HGNC:43540|Ensembl:ENSG00000263795|miRBase:MI0019116 +100847015 MIR5691 HGNC:HGNC:43545|Ensembl:ENSG00000264984|miRBase:MI0019296 +100847016 MIR5695 HGNC:HGNC:43548|Ensembl:ENSG00000266721|miRBase:MI0019302 +100847017 MIR5692C2 HGNC:HGNC:43448|Ensembl:ENSG00000266668|miRBase:MI0019289 +100847018 MIR5585 HGNC:HGNC:43452|Ensembl:ENSG00000266203|miRBase:MI0019142 +100847019 MIR5687 HGNC:HGNC:43457|Ensembl:ENSG00000265135|miRBase:MI0019291 +100847020 MIR5582 HGNC:HGNC:43461|Ensembl:ENSG00000263540|miRBase:MI0019138 +100847021 MIR5002 HGNC:HGNC:43470|Ensembl:ENSG00000266383|miRBase:MI0017868 +100847022 MIR5093 HGNC:HGNC:43474|Ensembl:ENSG00000266307|miRBase:MI0017982 +100847023 MIR5091 HGNC:HGNC:43478|Ensembl:ENSG00000266240|miRBase:MI0017980 +100847024 MIR5698 HGNC:HGNC:43487|Ensembl:ENSG00000263987|miRBase:MI0019305 +100847025 MIR5583-1 HGNC:HGNC:43491|Ensembl:ENSG00000266148|miRBase:MI0019139 +100847026 MIR5006 HGNC:HGNC:43495|Ensembl:ENSG00000284584|miRBase:MI0017873 +100847027 MIR5705 HGNC:HGNC:43504|Ensembl:ENSG00000263981|miRBase:MI0019313 +100847028 MIR5587 HGNC:HGNC:43508|Ensembl:ENSG00000266124|miRBase:MI0019144 +100847029 MIR5003 HGNC:HGNC:43512|Ensembl:ENSG00000265160|miRBase:MI0017869 +100847030 MIR548AT HGNC:HGNC:43517|Ensembl:ENSG00000264314|miRBase:MI0019137 +100847031 MIR5700 HGNC:HGNC:43521|Ensembl:ENSG00000266099|miRBase:MI0019307 +100847032 MIR5707 HGNC:HGNC:43449|Ensembl:ENSG00000265598|miRBase:MI0019315 +100847033 MIR4436B2 HGNC:HGNC:43451|Ensembl:ENSG00000263881|miRBase:MI0019110 +100847034 MIR5683 HGNC:HGNC:43453|Ensembl:ENSG00000283616|miRBase:MI0019284 +100847035 MIR548AR HGNC:HGNC:43455|Ensembl:ENSG00000264539|miRBase:MI0019131 +100847036 MIR5186 HGNC:HGNC:43459|Ensembl:ENSG00000264330|miRBase:MI0018165 +100847037 MIR5001 HGNC:HGNC:43462|Ensembl:ENSG00000284407|miRBase:MI0017867 +100847038 MIR5692A2 HGNC:HGNC:43466|Ensembl:ENSG00000264512|miRBase:MI0019298 +100847039 MIR5092 HGNC:HGNC:43467|Ensembl:ENSG00000264986|miRBase:MI0017981 +100847040 MIR5704 HGNC:HGNC:43469|Ensembl:ENSG00000265859|miRBase:MI0019312 +100847041 MIR3680-2 HGNC:HGNC:43472|Ensembl:ENSG00000266758|miRBase:MI0019113 +100847042 MIR5572 HGNC:HGNC:43476|Ensembl:ENSG00000284059|miRBase:MI0019117 +100847043 MIR5682 HGNC:HGNC:43477|Ensembl:ENSG00000264477|miRBase:MI0019282 +100847044 MIR5087 HGNC:HGNC:43480|Ensembl:ENSG00000283676|miRBase:MI0017976 +100847045 MIR548AU HGNC:HGNC:43483|Ensembl:ENSG00000283146|miRBase:MI0019145 +100847046 MIR5010 HGNC:HGNC:43484|Ensembl:ENSG00000283929|miRBase:MI0017878 +100847047 MIR4666B HGNC:HGNC:43486|Ensembl:ENSG00000264090|miRBase:MI0019299 +100847048 MIR5690 HGNC:HGNC:43490|Ensembl:ENSG00000265527|miRBase:MI0019295 +100847049 MIR4999 HGNC:HGNC:43494|Ensembl:ENSG00000265390|miRBase:MI0017865 +100847050 MIR5191 HGNC:HGNC:43497|Ensembl:ENSG00000264802|miRBase:MI0018170 +100847051 MIR5194 HGNC:HGNC:43498|Ensembl:ENSG00000264653|miRBase:MI0018173 +100847052 MIR664B HGNC:HGNC:43501|Ensembl:ENSG00000284450|miRBase:MI0019134 +100847053 MIR5702 HGNC:HGNC:43503|Ensembl:ENSG00000263363|miRBase:MI0019309 +100847054 MIR5588 HGNC:HGNC:43505|Ensembl:ENSG00000264614|miRBase:MI0019147 +100847055 MIR5697 HGNC:HGNC:43509|Ensembl:ENSG00000265521|miRBase:MI0019304 +100847056 MIR5708 HGNC:HGNC:43511|Ensembl:ENSG00000265588|miRBase:MI0019316 +100847057 MIR5189 HGNC:HGNC:43515|Ensembl:ENSG00000263456|miRBase:MI0018168 +100847058 MIR5681A HGNC:HGNC:43518|Ensembl:ENSG00000266502|miRBase:MI0019281 +100847059 MIR5094 HGNC:HGNC:43519|Ensembl:ENSG00000264966|miRBase:MI0017983 +100847060 MIR5701-1 HGNC:HGNC:43522|Ensembl:ENSG00000266545|miRBase:MI0019308 +100847061 MIR4536-2 HGNC:HGNC:43525|Ensembl:ENSG00000266328|miRBase:MI0019149 +100847062 MIR5195 HGNC:HGNC:43526|Ensembl:ENSG00000265929|miRBase:MI0018174 +100847063 MIR548AX HGNC:HGNC:43528|Ensembl:ENSG00000263652|miRBase:MI0019286 +100847064 MIR5694 HGNC:HGNC:43530|Ensembl:ENSG00000265993|miRBase:MI0019301 +100847065 MIR5591 HGNC:HGNC:43531|Ensembl:ENSG00000264621|miRBase:MI0019151 +100847066 MIR5692A1 HGNC:HGNC:43533|Ensembl:ENSG00000266318|miRBase:MI0019297 +100847067 MIR5089 HGNC:HGNC:43536|Ensembl:ENSG00000264999|miRBase:MI0017978 +100847068 MIR548AO HGNC:HGNC:43539|Ensembl:ENSG00000263372|miRBase:MI0017871 +100847069 MIR5590 HGNC:HGNC:43541|Ensembl:ENSG00000263783|miRBase:MI0019150 +100847070 MIR5196 HGNC:HGNC:43542|Ensembl:ENSG00000284034|miRBase:MI0018175 +100847071 MIR5684 HGNC:HGNC:43544|Ensembl:ENSG00000263800|miRBase:MI0019285 +100847072 MIR5008 HGNC:HGNC:43546|Ensembl:ENSG00000264483|miRBase:MI0017876 +100847073 MIR5090 HGNC:HGNC:43547|Ensembl:ENSG00000284176|miRBase:MI0017979 +100847074 MIR5088 HGNC:HGNC:43489|Ensembl:ENSG00000274306|miRBase:MI0017977 +100847075 MIR5685 HGNC:HGNC:43543|Ensembl:ENSG00000264056|miRBase:MI0019287 +100847076 MIR5580 HGNC:HGNC:43482|Ensembl:ENSG00000266431|miRBase:MI0019135 +100847077 MIR5688 HGNC:HGNC:43463|Ensembl:ENSG00000264084|miRBase:MI0019292 +100847078 MIR548AQ HGNC:HGNC:43488|Ensembl:ENSG00000265470|miRBase:MI0019130 +100847079 MIR5193 HGNC:HGNC:43534|Ensembl:ENSG00000283726|miRBase:MI0018172 +100847080 MIR5190 HGNC:HGNC:43549|Ensembl:ENSG00000266146|miRBase:MI0018169 +100847081 MIR5703 HGNC:HGNC:43475|Ensembl:ENSG00000284092|miRBase:MI0019310 +100847082 MIR5692C1 HGNC:HGNC:43506|Ensembl:ENSG00000265924|miRBase:MI0019288 +100847083 MIR548AV HGNC:HGNC:43537|Ensembl:ENSG00000263750|miRBase:MI0019152 +100847084 MIR548AP HGNC:HGNC:43465|Ensembl:ENSG00000264406|miRBase:MI0017875 +100847085 MIR5706 HGNC:HGNC:43500|Ensembl:ENSG00000264536|miRBase:MI0019314 +100847086 MIR5699 HGNC:HGNC:43456|Ensembl:ENSG00000263511|miRBase:MI0019306 +100847087 MIR5192 HGNC:HGNC:43473|Ensembl:ENSG00000266097|miRBase:MI0018171 +100847088 MIR5586 HGNC:HGNC:43493|Ensembl:ENSG00000263629|miRBase:MI0019143 +100847089 MIR5584 HGNC:HGNC:43507|Ensembl:ENSG00000263381|miRBase:MI0019141 +100847090 MIR5187 HGNC:HGNC:43523|Ensembl:ENSG00000284035|miRBase:MI0018166 +100847091 MIR5681B HGNC:HGNC:43538|Ensembl:ENSG00000283505|miRBase:MI0019293 +100847092 MIR548AS HGNC:HGNC:43550|Ensembl:ENSG00000263741|miRBase:MI0019132 +100847093 MIR5589 HGNC:HGNC:43514|Ensembl:ENSG00000266204|miRBase:MI0019148 +100852393 MRT29 MIM:614333 +100852394 MRT33 MIM:614341 +100852395 MRT19 MIM:614343|HGNC:HGNC:39153 +100852396 MRT28 MIM:614347|HGNC:HGNC:39162 +100852397 MRT27 MIM:614340|HGNC:HGNC:39161 +100852398 MRT23 MIM:614344|HGNC:HGNC:39157 +100852399 MRT31 MIM:614329 +100852400 MRT32 MIM:614339 +100852401 MRT30 MIM:614342 +100852402 MRT24 MIM:614345|HGNC:HGNC:39158 +100852403 MRT25 MIM:614346|HGNC:HGNC:39159 +100852404 DEL17Q11.2 MIM:613675 +100852405 RNF185-AS1 HGNC:HGNC:41161 +100852406 POTEH-AS1 HGNC:HGNC:40058 +100852407 CARS-AS1 HGNC:HGNC:40125 +100852408 EGFLAM-AS4 HGNC:HGNC:41166|Ensembl:ENSG00000248730 +100852409 NEGR1-IT1 HGNC:HGNC:41432|Ensembl:ENSG00000228853 +100852410 ZRANB2-AS2 HGNC:HGNC:43595|Ensembl:ENSG00000229956 +100856791 LOC100856791 - +100856809 OR3A5P HGNC:HGNC:8286 +100856810 ELOBP3 HGNC:HGNC:39721 +100856811 NRG1-IT1 HGNC:HGNC:43633 +100856877 SETP15 HGNC:HGNC:42934 +100856878 SETP21 HGNC:HGNC:42940 +100856881 MTND1P32 HGNC:HGNC:42081 +100859919 LOC100859919 - +100859920 HIGD1AP3 HGNC:HGNC:42998 +100859921 LINC00536 HGNC:HGNC:43645|Ensembl:ENSG00000249917 +100859922 ERVK11-1 HGNC:HGNC:43647 +100859924 SUMO2P2 HGNC:HGNC:39012 +100859925 COX5BP8 HGNC:HGNC:39083 +100859926 NANOGNBP1 HGNC:HGNC:42158 +100859927 AAA4 MIM:614375 +100859928 BMIQ16 MIM:613444 +100859930 HEIH HGNC:HGNC:45049|Ensembl:ENSG00000278970 +100861402 CERS6-AS1 HGNC:HGNC:44485|Ensembl:ENSG00000227617 +100861412 FSBP MIM:616306|HGNC:HGNC:43653|Ensembl:ENSG00000265817|Vega:OTTHUMG00000178341 +100861429 YRDCP3 HGNC:HGNC:39921 +100861430 PDCD6IPP1 HGNC:HGNC:49872 +100861431 YBX1P7 HGNC:HGNC:42428 +100861434 USP9YP13 HGNC:HGNC:38721 +100861435 SRIP3 HGNC:HGNC:38735 +100861436 PRPS1P1 HGNC:HGNC:39427 +100861439 CTRCT37 MIM:614422 +100861440 DFNB96 MIM:614414|HGNC:HGNC:39437 +100861443 DNAJC19P3 HGNC:HGNC:45066 +100861445 DNAJC19P2 HGNC:HGNC:45065 +100861449 DNAJC19P6 HGNC:HGNC:45069 +100861453 DNAJC19P5 HGNC:HGNC:45068 +100861455 DNAJC19P8 HGNC:HGNC:45071 +100861458 DNAJC19P7 HGNC:HGNC:45070 +100861467 ERVK-13 HGNC:HGNC:39008 +100861468 LINC00492 HGNC:HGNC:43429|Ensembl:ENSG00000250958 +100861469 PTP4A1P3 HGNC:HGNC:41930 +100861470 YBX1P9 HGNC:HGNC:42430 +100861476 YBX1P8 HGNC:HGNC:42429 +100861485 DUTP3 HGNC:HGNC:39516 +100861504 LINC00538 MIM:614635|HGNC:HGNC:43655 +100861506 LINC00903 HGNC:HGNC:40351 +100861507 FTCD-AS1 HGNC:HGNC:40243 +100861510 LRRC3-AS1 HGNC:HGNC:43636|Ensembl:ENSG00000229356 +100861512 CDKN1A-AS1 HGNC:HGNC:42399 +100861513 ZMYM4-AS1 HGNC:HGNC:40624 +100861514 ELMO1-AS1 HGNC:HGNC:40765|Ensembl:ENSG00000224101 +100861515 TRAPPC12-AS1 HGNC:HGNC:41046 +100861516 RAI1-AS1 HGNC:HGNC:40496|Ensembl:ENSG00000237328 +100861517 OCIAD1-AS1 HGNC:HGNC:40751 +100861518 P4HA2-AS1 HGNC:HGNC:43560|Ensembl:ENSG00000237714 +100861519 GDNF-AS1 HGNC:HGNC:43592|Ensembl:ENSG00000248587 +100861520 POU6F2-AS1 HGNC:HGNC:40979|Ensembl:ENSG00000224122 +100861522 LINC00489 HGNC:HGNC:43426|Ensembl:ENSG00000225759 +100861523 RPS6KA2-AS1 HGNC:HGNC:40511 +100861529 HHPP MIM:144110 +100861530 UFL1-AS1 HGNC:HGNC:41007 +100861532 RNA45SN5 HGNC:HGNC:53530 +100861540 CYP3A7-CYP3A51P HGNC:HGNC:51504|Ensembl:ENSG00000282301|Vega:OTTHUMG00000191417 +100861541 DOCK9-AS2 HGNC:HGNC:43696 +100861542 LINC00554 HGNC:HGNC:43697|Ensembl:ENSG00000260738 +100861543 LINC00555 HGNC:HGNC:43699 +100861544 LINC00557 HGNC:HGNC:43701|Ensembl:ENSG00000260962 +100861545 LINC00561 HGNC:HGNC:43705 +100861546 LINC00564 HGNC:HGNC:43708|Ensembl:ENSG00000260094 +100861547 LINC00566 HGNC:HGNC:43710|Ensembl:ENSG00000261498 +100861548 PINK1-AS HGNC:HGNC:38872|Ensembl:ENSG00000117242 +100861549 LINC00562 HGNC:HGNC:43706|Ensembl:ENSG00000260388 +100861550 PLUT HGNC:HGNC:43698 +100861551 LINC00556 HGNC:HGNC:43700 +100861552 LINC00558 HGNC:HGNC:43702|Ensembl:ENSG00000261517 +100861553 LINC00560 HGNC:HGNC:43704 +100861554 LINC00563 HGNC:HGNC:43707|Ensembl:ENSG00000261097 +100861555 LINC00565 HGNC:HGNC:43709|Ensembl:ENSG00000260910 +100861556 YBX1P3 HGNC:HGNC:42424 +100861563 SCAANT1 MIM:614481|HGNC:HGNC:43718 +100861569 YBX1P5 HGNC:HGNC:42426 +100861573 LINC00572 HGNC:HGNC:43722|Ensembl:ENSG00000224405 +100861574 SNRPGP6 HGNC:HGNC:39325 +100862662 ALDH1L1-AS2 HGNC:HGNC:42446|Ensembl:ENSG00000246022 +100862663 RNY4P21 HGNC:HGNC:42471 +100862664 RNY4P24 HGNC:HGNC:42474 +100862665 RNY4P25 HGNC:HGNC:42475 +100862666 RNY1P2 HGNC:HGNC:42479 +100862667 RNY1P5 HGNC:HGNC:42482 +100862668 RNY3P2 HGNC:HGNC:42486 +100862669 RNY3P3 HGNC:HGNC:42487 +100862670 RNY3P7 HGNC:HGNC:42491 +100862671 TMEM265 HGNC:HGNC:51241|Ensembl:ENSG00000281991|Vega:OTTHUMG00000191414 +100862672 RNY3P9 HGNC:HGNC:42493 +100862673 RNY4P30 HGNC:HGNC:42498 +100862674 RNY4P31 HGNC:HGNC:42499 +100862675 RNU4-9P HGNC:HGNC:42507 +100862676 RNU4-10P HGNC:HGNC:42508 +100862677 RBMX2P4 HGNC:HGNC:39926 +100862679 NAALADL2-AS3 HGNC:HGNC:41014|Ensembl:ENSG00000230292 +100862680 LINC00507 HGNC:HGNC:43558|Ensembl:ENSG00000256193 +100862681 RP63 MIM:614494|HGNC:HGNC:49652 +100862682 LOC100862682 - +100862683 ERVK-25 HGNC:HGNC:39039 +100862684 ERVK-24 HGNC:HGNC:39038 +100862685 ERVK-19 HGNC:HGNC:39026 +100862686 ERVK-17 HGNC:HGNC:39024 +100862687 ERVK-14 HGNC:HGNC:39019 +100862688 ERVK-11 HGNC:HGNC:39006 +100862689 ERVK-3 HGNC:HGNC:39002 +100862690 ERVK-1 HGNC:HGNC:39000 +100862691 ERVE-2 HGNC:HGNC:39048 +100862692 DIP2A-IT1 HGNC:HGNC:41430|Ensembl:ENSG00000223692 +100862693 ERVPABLB-1 HGNC:HGNC:39042 +100862694 ERVS71-1 HGNC:HGNC:41525 +100862695 ERVW-5 HGNC:HGNC:39044 +100862696 ERVW-3 HGNC:HGNC:39041 +100862697 ERVK3-2 HGNC:HGNC:39040 +100862698 ERVH-7 HGNC:HGNC:39059 +100862699 ERVH-5 HGNC:HGNC:39057 +100862700 ERVE-3 HGNC:HGNC:39049 +100862704 LINC00441 HGNC:HGNC:42778|Ensembl:ENSG00000231473 +100862705 KANK1P1 HGNC:HGNC:52337 +100862706 CATMANS MIM:302380 +100862725 TIMM9P3 HGNC:HGNC:39930 +100862726 TIMM9P1 HGNC:HGNC:39928 +100862727 TIMM9P2 HGNC:HGNC:39929 +100862728 UPK1A-AS1 HGNC:HGNC:40603|Ensembl:ENSG00000226510 +100862850 EEF1A1P39 HGNC:HGNC:37917 +100862852 SLAMF6P1 HGNC:HGNC:32012 +100862853 MTND4P13 HGNC:HGNC:42222 +100862854 MTND5P16 HGNC:HGNC:42278 +100862855 COX6CP5 HGNC:HGNC:42791 +100873064 AIMP1P2 HGNC:HGNC:43693 +100873065 PTCHD1-AS HGNC:HGNC:37703 +100873165 SRGAP2-AS1 HGNC:HGNC:40902|Ensembl:ENSG00000230806 +100873166 SETP7 HGNC:HGNC:42926 +100873168 MTCYBP2 HGNC:HGNC:38807 +100873169 MTCYBP4 HGNC:HGNC:41923 +100873170 MTND1P2 HGNC:HGNC:42051 +100873171 MTND1P4 HGNC:HGNC:42053 +100873172 MTND1P7 HGNC:HGNC:42102 +100873173 MTND1P6 HGNC:HGNC:42103 +100873174 MTND1P5 HGNC:HGNC:42104 +100873175 MTND2P4 HGNC:HGNC:42105 +100873176 MTND2P5 HGNC:HGNC:42106 +100873177 MTND2P6 HGNC:HGNC:42107 +100873178 MTND2P8 HGNC:HGNC:42109 +100873179 MTND2P7 HGNC:HGNC:42141 +100873180 MTND3P2 HGNC:HGNC:42142 +100873181 MTND3P4 HGNC:HGNC:42144 +100873182 MTND3P6 HGNC:HGNC:42146 +100873183 MTND3P7 HGNC:HGNC:42147 +100873184 MTND3P9 HGNC:HGNC:42149 +100873185 MTND3P8 HGNC:HGNC:42153 +100873186 MTND3P5 HGNC:HGNC:42154 +100873187 MTND3P3 HGNC:HGNC:42155 +100873188 MTND4P2 HGNC:HGNC:42189 +100873189 MTND4P3 HGNC:HGNC:42190 +100873190 MTND4P4 HGNC:HGNC:42191 +100873191 MTND4P5 HGNC:HGNC:42192 +100873192 MTND4P6 HGNC:HGNC:42193 +100873193 MTND4P9 HGNC:HGNC:42226 +100873194 MTND4P8 HGNC:HGNC:42227 +100873195 MTND4P7 HGNC:HGNC:42234 +100873196 MTND5P6 HGNC:HGNC:42268 +100873197 MTND5P7 HGNC:HGNC:42269 +100873198 MTND5P8 HGNC:HGNC:42270 +100873199 MTND5P9 HGNC:HGNC:42305 +100873200 MTND5P4 HGNC:HGNC:42306 +100873201 MTND5P5 HGNC:HGNC:42307 +100873202 MTCO2P2 HGNC:HGNC:25354 +100873203 MTCO2P3 HGNC:HGNC:39576 +100873204 MTCYBP3 HGNC:HGNC:39579 +100873205 MTCO1P3 HGNC:HGNC:39604 +100873206 MTND5P1 HGNC:HGNC:39644 +100873207 MTCO3P2 HGNC:HGNC:39681 +100873208 MTND3P1 HGNC:HGNC:39856 +100873209 MTND5P2 HGNC:HGNC:41919 +100873210 MTND5P3 HGNC:HGNC:42034 +100873211 MTND4P1 HGNC:HGNC:42035 +100873212 MTND1P11 HGNC:HGNC:42060 +100873213 MTND1P16 HGNC:HGNC:42065 +100873214 MTND1P26 HGNC:HGNC:42075 +100873215 MTND1P28 HGNC:HGNC:42077 +100873216 MTND1P29 HGNC:HGNC:42078 +100873217 MTND1P31 HGNC:HGNC:42080 +100873218 MTND1P33 HGNC:HGNC:42082 +100873219 MTND1P34 HGNC:HGNC:42090 +100873220 MTND1P19 HGNC:HGNC:42094 +100873221 MTND1P9 HGNC:HGNC:42099 +100873222 MTND2P11 HGNC:HGNC:42112 +100873223 MTND2P14 HGNC:HGNC:42115 +100873224 MTND2P18 HGNC:HGNC:42119 +100873225 MTND2P19 HGNC:HGNC:42120 +100873226 MTND2P20 HGNC:HGNC:42121 +100873227 MTND2P21 HGNC:HGNC:42122 +100873228 MTND2P22 HGNC:HGNC:42123 +100873229 MTND2P23 HGNC:HGNC:42124 +100873230 MTND2P24 HGNC:HGNC:42125 +100873231 MTND2P25 HGNC:HGNC:42126 +100873232 MTND2P27 HGNC:HGNC:42128 +100873233 MTND2P29 HGNC:HGNC:42130 +100873234 MTND2P30 HGNC:HGNC:42131 +100873235 MTND2P31 HGNC:HGNC:42132 +100873236 MTND2P33 HGNC:HGNC:42134 +100873237 MTND2P32 HGNC:HGNC:42139 +100873238 MTND2P10 HGNC:HGNC:42140 +100873239 MTND3P10 HGNC:HGNC:42150 +100873240 MTND4P15 HGNC:HGNC:42202 +100873241 MTND4P16 HGNC:HGNC:42203 +100873242 MTND4P17 HGNC:HGNC:42204 +100873243 MTND4P21 HGNC:HGNC:42208 +100873244 MTND4P22 HGNC:HGNC:42209 +100873245 MTND4P23 HGNC:HGNC:42210 +100873246 MTND4P25 HGNC:HGNC:42212 +100873247 MTND4P26 HGNC:HGNC:42213 +100873248 MTND4P27 HGNC:HGNC:42214 +100873249 MTND4P28 HGNC:HGNC:42215 +100873250 MTND4P29 HGNC:HGNC:42216 +100873251 MTND4P30 HGNC:HGNC:42217 +100873252 MTND4P31 HGNC:HGNC:42218 +100873253 MTND4P32 HGNC:HGNC:42219 +100873254 MTND4P24 HGNC:HGNC:42220 +100873255 MTND4P11 HGNC:HGNC:42223 +100873256 MTND4P10 HGNC:HGNC:42225 +100873257 MTND5P12 HGNC:HGNC:42274 +100873258 MTND5P14 HGNC:HGNC:42276 +100873259 MTND5P15 HGNC:HGNC:42277 +100873260 MTND5P22 HGNC:HGNC:42284 +100873261 MTND5P23 HGNC:HGNC:42285 +100873262 MTND5P24 HGNC:HGNC:42286 +100873263 MTND5P25 HGNC:HGNC:42287 +100873264 MTND5P27 HGNC:HGNC:42289 +100873265 MTND5P29 HGNC:HGNC:42291 +100873266 MTND5P30 HGNC:HGNC:42292 +100873267 MTND5P31 HGNC:HGNC:42293 +100873268 MTND5P26 HGNC:HGNC:42295 +100873269 MTND5P20 HGNC:HGNC:42300 +100873270 MTND5P19 HGNC:HGNC:42301 +100873271 MTND5P18 HGNC:HGNC:42302 +100873272 MTND5P13 HGNC:HGNC:42304 +100873273 RNA5SP18 HGNC:HGNC:42586 +100873274 RNA5SP19 HGNC:HGNC:42587 +100873275 RNA5SP20 HGNC:HGNC:42588 +100873276 RNA5SP21 HGNC:HGNC:42589 +100873277 RNA5SP22 HGNC:HGNC:42590 +100873278 RNA5SP23 HGNC:HGNC:42591 +100873279 RNA5SP40 HGNC:HGNC:42816 +100873280 RNA5SP41 HGNC:HGNC:42817 +100873281 RNA5SP42 HGNC:HGNC:42818 +100873282 RNA5SP43 HGNC:HGNC:42819 +100873283 RNA5SP44 HGNC:HGNC:42820 +100873284 RNA5SP45 HGNC:HGNC:42821 +100873285 RNA5SP46 HGNC:HGNC:42822 +100873286 RNA5SP47 HGNC:HGNC:42823 +100873287 RNA5SP48 HGNC:HGNC:42824 +100873288 RNA5SP49 HGNC:HGNC:42825 +100873289 RNA5SP51 HGNC:HGNC:42828 +100873290 RNA5SP52 HGNC:HGNC:42829 +100873291 RNA5SP53 HGNC:HGNC:42830 +100873292 RNA5SP54 HGNC:HGNC:42831 +100873293 RNA5SP55 HGNC:HGNC:42832 +100873294 RNA5SP56 HGNC:HGNC:42833 +100873295 RNA5SP60 HGNC:HGNC:42837 +100873296 RNA5SP61 HGNC:HGNC:42838 +100873297 RNA5SP62 HGNC:HGNC:42839 +100873298 RNA5SP63 HGNC:HGNC:42840 +100873299 RNA5SP64 HGNC:HGNC:42841 +100873300 RNA5SP65 HGNC:HGNC:42842 +100873301 RNA5SP66 HGNC:HGNC:42843 +100873302 RNA5SP67 HGNC:HGNC:42844 +100873303 RNA5SP68 HGNC:HGNC:42845 +100873304 RNA5SP69 HGNC:HGNC:42846 +100873305 RNA5SP71 HGNC:HGNC:42848 +100873306 RNA5SP72 HGNC:HGNC:42849 +100873307 RNA5SP73 HGNC:HGNC:42850 +100873308 RNA5SP74 HGNC:HGNC:42851 +100873309 RNA5SP75 HGNC:HGNC:42852 +100873310 RNA5SP76 HGNC:HGNC:42853 +100873311 RNA5SP77 HGNC:HGNC:42854 +100873312 RNA5SP78 HGNC:HGNC:42855 +100873313 RNA5SP79 HGNC:HGNC:42856 +100873314 RNA5SP80 HGNC:HGNC:42857 +100873316 RNA5SP82 HGNC:HGNC:42859 +100873317 RNA5SP84 HGNC:HGNC:42882 +100873318 RNA5SP85 HGNC:HGNC:42883 +100873319 RNA5SP86 HGNC:HGNC:42884 +100873320 RNA5SP87 HGNC:HGNC:42885 +100873321 RNA5SP88 HGNC:HGNC:42886 +100873322 RNA5SP89 HGNC:HGNC:42887 +100873323 RNA5SP90 HGNC:HGNC:42888 +100873324 RNA5SP91 HGNC:HGNC:42889 +100873325 RNA5SP92 HGNC:HGNC:42890 +100873326 RNA5SP93 HGNC:HGNC:42891 +100873327 RNA5SP94 HGNC:HGNC:42892 +100873328 RNA5SP95 HGNC:HGNC:42893 +100873329 RNA5SP96 HGNC:HGNC:42894 +100873330 RNA5SP97 HGNC:HGNC:42895 +100873331 RNA5SP98 HGNC:HGNC:42896 +100873332 MTND6P21 HGNC:HGNC:39639 +100873333 SEPT2P1 HGNC:HGNC:40017 +100873334 RNA5-8SP3 HGNC:HGNC:41957 +100873335 RNA5-8SP5 HGNC:HGNC:41959 +100873336 RNA5-8SP6 HGNC:HGNC:41960 +100873337 MTND1P14 HGNC:HGNC:42063 +100873338 MTND1P18 HGNC:HGNC:42067 +100873339 MTND1P20 HGNC:HGNC:42069 +100873340 MTND1P21 HGNC:HGNC:42070 +100873341 MTND1P24 HGNC:HGNC:42073 +100873342 MTND1P17 HGNC:HGNC:42095 +100873343 MTND1P10 HGNC:HGNC:42097 +100873344 MTND2P12 HGNC:HGNC:42113 +100873345 MTND2P13 HGNC:HGNC:42114 +100873346 MTND2P15 HGNC:HGNC:42116 +100873347 MTND2P16 HGNC:HGNC:42117 +100873348 MTND2P17 HGNC:HGNC:42118 +100873349 MTND2P26 HGNC:HGNC:42127 +100873350 MTND4P18 HGNC:HGNC:42205 +100873351 MTND4P19 HGNC:HGNC:42206 +100873352 MTND4P20 HGNC:HGNC:42207 +100873353 MTND5P17 HGNC:HGNC:42279 +100873354 MTND5P21 HGNC:HGNC:42296 +100873355 TEKT4P3 HGNC:HGNC:42330 +100873356 RNA5SP24 HGNC:HGNC:42600 +100873357 RNA5SP25 HGNC:HGNC:42601 +100873358 RNA5SP26 HGNC:HGNC:42602 +100873359 RNA5SP27 HGNC:HGNC:42603 +100873360 RNA5SP28 HGNC:HGNC:42604 +100873361 RNA5SP29 HGNC:HGNC:42605 +100873362 RNA5SP30 HGNC:HGNC:42606 +100873363 RNA5SP31 HGNC:HGNC:42607 +100873365 RNA5SP33 HGNC:HGNC:42609 +100873366 RNA5SP34 HGNC:HGNC:42610 +100873367 RNA5SP35 HGNC:HGNC:42611 +100873368 RNA5SP36 HGNC:HGNC:42612 +100873369 RNA5SP37 HGNC:HGNC:42613 +100873370 RNA5SP38 HGNC:HGNC:42614 +100873371 RNA5SP39 HGNC:HGNC:42615 +100873372 RNA5SP101 HGNC:HGNC:42899 +100873373 RNA5SP102 HGNC:HGNC:42900 +100873374 RNA5SP103 HGNC:HGNC:42901 +100873375 RNA5SP104 HGNC:HGNC:42902 +100873376 RNA5SP105 HGNC:HGNC:42903 +100873377 RNA5SP107 HGNC:HGNC:42905 +100873378 RNA5SP108 HGNC:HGNC:42906 +100873379 RNA5SP109 HGNC:HGNC:42907 +100873380 RNA5SP110 HGNC:HGNC:42908 +100873381 RNA5SP111 HGNC:HGNC:42909 +100873382 RNA5SP112 HGNC:HGNC:42910 +100873383 RNA5SP113 HGNC:HGNC:42911 +100873384 RNA5SP114 HGNC:HGNC:42912 +100873385 RNA5SP115 HGNC:HGNC:42913 +100873386 RNA5SP116 HGNC:HGNC:42914 +100873387 RNA5SP117 HGNC:HGNC:42915 +100873388 RNA5SP118 HGNC:HGNC:42916 +100873389 RNA5SP119 HGNC:HGNC:42917 +100873390 RNA5SP120 HGNC:HGNC:42918 +100873391 RNA5SP121 HGNC:HGNC:42919 +100873392 RNA5SP122 HGNC:HGNC:42920 +100873393 RNA5SP123 HGNC:HGNC:43023 +100873394 RNA5SP124 HGNC:HGNC:43024 +100873395 RNA5SP125 HGNC:HGNC:43025 +100873396 RNA5SP126 HGNC:HGNC:43026 +100873397 RNA5SP127 HGNC:HGNC:43027 +100873398 RNA5SP128 HGNC:HGNC:43028 +100873399 RNA5SP129 HGNC:HGNC:43029 +100873400 RNA5SP131 HGNC:HGNC:43031 +100873401 RNA5SP132 HGNC:HGNC:43032 +100873402 RNA5SP133 HGNC:HGNC:43033 +100873403 RNA5SP135 HGNC:HGNC:43035 +100873404 RNA5SP136 HGNC:HGNC:43036 +100873405 RNA5SP137 HGNC:HGNC:43037 +100873406 RNA5SP138 HGNC:HGNC:43038 +100873407 RNA5SP139 HGNC:HGNC:43039 +100873408 RNA5SP141 HGNC:HGNC:43041 +100873409 RNA5SP142 HGNC:HGNC:43042 +100873410 RNA5SP143 HGNC:HGNC:43043 +100873411 RNA5SP144 HGNC:HGNC:43044 +100873412 RNA5SP145 HGNC:HGNC:43045 +100873413 RNA5SP146 HGNC:HGNC:43046 +100873414 RNA5SP147 HGNC:HGNC:43047 +100873415 RNA5SP148 HGNC:HGNC:43048 +100873416 RNA5SP150 HGNC:HGNC:43050 +100873417 RNA5SP151 HGNC:HGNC:43051 +100873418 RNA5SP152 HGNC:HGNC:43052 +100873419 RNA5SP153 HGNC:HGNC:43053 +100873420 RNA5SP154 HGNC:HGNC:43054 +100873421 RNA5SP155 HGNC:HGNC:43055 +100873422 RNA5SP156 HGNC:HGNC:43056 +100873423 RNA5SP157 HGNC:HGNC:43057 +100873424 RNA5SP158 HGNC:HGNC:43058 +100873425 RNA5SP159 HGNC:HGNC:43059 +100873426 RNA5SP160 HGNC:HGNC:43060 +100873427 RNA5SP162 HGNC:HGNC:43062 +100873428 RNA5SP163 HGNC:HGNC:43063 +100873429 RNA5SP164 HGNC:HGNC:43064 +100873430 RNA5SP165 HGNC:HGNC:43065 +100873431 RNA5SP166 HGNC:HGNC:43066 +100873432 RNA5SP167 HGNC:HGNC:43067 +100873433 RNA5SP168 HGNC:HGNC:43068 +100873434 RNA5SP169 HGNC:HGNC:43069 +100873435 RNA5SP170 HGNC:HGNC:43070 +100873436 RNA5SP171 HGNC:HGNC:43071 +100873437 RNA5SP173 HGNC:HGNC:43073 +100873438 RNA5SP176 HGNC:HGNC:43076 +100873439 RNA5SP177 HGNC:HGNC:43077 +100873440 RNA5SP178 HGNC:HGNC:43078 +100873441 RNA5SP179 HGNC:HGNC:43079 +100873442 RNA5SP180 HGNC:HGNC:43080 +100873443 RNA5SP181 HGNC:HGNC:43081 +100873444 RNA5SP182 HGNC:HGNC:43082 +100873445 RNA5SP183 HGNC:HGNC:43083 +100873446 RNA5SP184 HGNC:HGNC:43084 +100873447 RNA5SP185 HGNC:HGNC:43085 +100873448 RNA5SP186 HGNC:HGNC:43086 +100873449 RNA5SP187 HGNC:HGNC:43087 +100873450 RNA5SP188 HGNC:HGNC:43088 +100873451 RNA5SP189 HGNC:HGNC:43089 +100873452 RNA5SP190 HGNC:HGNC:43090 +100873453 RNA5SP191 HGNC:HGNC:43091 +100873454 RNA5SP192 HGNC:HGNC:43092 +100873455 RNA5SP193 HGNC:HGNC:43093 +100873456 RNA5SP194 HGNC:HGNC:43094 +100873457 RNA5SP195 HGNC:HGNC:43095 +100873458 RNA5SP196 HGNC:HGNC:43096 +100873459 RNA5SP197 HGNC:HGNC:43097 +100873460 RNA5SP198 HGNC:HGNC:43098 +100873461 RNA5SP200 HGNC:HGNC:43100 +100873462 RNA5SP201 HGNC:HGNC:43101 +100873463 RNA5SP202 HGNC:HGNC:43102 +100873464 RNA5SP203 HGNC:HGNC:43103 +100873465 RNA5SP204 HGNC:HGNC:43104 +100873466 RNA5SP205 HGNC:HGNC:43105 +100873467 RNA5SP207 HGNC:HGNC:43107 +100873468 RNA5SP208 HGNC:HGNC:43108 +100873469 RNA5SP209 HGNC:HGNC:43109 +100873470 RNA5SP210 HGNC:HGNC:43110 +100873471 RNA5SP211 HGNC:HGNC:43111 +100873472 RNA5SP212 HGNC:HGNC:43112 +100873473 RNA5SP213 HGNC:HGNC:43113 +100873474 RNA5SP214 HGNC:HGNC:43114 +100873475 RNA5SP215 HGNC:HGNC:43115 +100873476 RNA5SP216 HGNC:HGNC:43116 +100873477 RNA5SP217 HGNC:HGNC:43117 +100873478 RNA5SP218 HGNC:HGNC:43118 +100873479 RNA5SP219 HGNC:HGNC:43119 +100873480 RNA5SP220 HGNC:HGNC:43120 +100873481 RNA5SP222 HGNC:HGNC:43122 +100873482 RNA5SP223 HGNC:HGNC:43123 +100873483 RNA5SP224 HGNC:HGNC:43124 +100873484 RNA5SP225 HGNC:HGNC:43125 +100873485 RNA5SP227 HGNC:HGNC:43127 +100873486 RNA5SP228 HGNC:HGNC:43128 +100873487 RNA5SP229 HGNC:HGNC:43129 +100873488 RNA5SP230 HGNC:HGNC:43130 +100873489 RNA5SP231 HGNC:HGNC:43131 +100873490 RNA5SP232 HGNC:HGNC:43132 +100873491 RNA5SP233 HGNC:HGNC:43133 +100873492 RNA5SP234 HGNC:HGNC:43134 +100873493 RNA5SP235 HGNC:HGNC:43135 +100873494 RNA5SP236 HGNC:HGNC:43136 +100873495 RNA5SP237 HGNC:HGNC:43137 +100873496 RNA5SP238 HGNC:HGNC:43138 +100873497 RNA5SP239 HGNC:HGNC:43139 +100873498 RNA5SP240 HGNC:HGNC:43140 +100873499 RNA5SP241 HGNC:HGNC:43141 +100873500 RNA5SP242 HGNC:HGNC:43142 +100873501 RNA5SP245 HGNC:HGNC:43145 +100873502 RNA5SP246 HGNC:HGNC:43146 +100873503 RNA5SP247 HGNC:HGNC:43147 +100873504 RNA5SP248 HGNC:HGNC:43148 +100873505 RNA5SP249 HGNC:HGNC:43149 +100873506 RNA5SP250 HGNC:HGNC:43150 +100873507 RNA5SP251 HGNC:HGNC:43151 +100873508 RNA5SP252 HGNC:HGNC:43152 +100873509 RNA5SP255 HGNC:HGNC:43155 +100873510 RNA5SP256 HGNC:HGNC:43156 +100873511 RNA5SP257 HGNC:HGNC:43157 +100873512 RNA5SP258 HGNC:HGNC:43158 +100873513 RNA5SP259 HGNC:HGNC:43159 +100873514 RNA5SP260 HGNC:HGNC:43160 +100873515 RNA5SP261 HGNC:HGNC:43161 +100873516 RNA5SP262 HGNC:HGNC:43162 +100873517 RNA5SP264 HGNC:HGNC:43164 +100873518 RNA5SP265 HGNC:HGNC:43165 +100873519 RNA5SP266 HGNC:HGNC:43166 +100873520 RNA5SP267 HGNC:HGNC:43167 +100873521 RNA5SP268 HGNC:HGNC:43168 +100873522 RNA5SP269 HGNC:HGNC:43169 +100873523 RNA5SP270 HGNC:HGNC:43170 +100873524 RNA5SP271 HGNC:HGNC:43171 +100873525 RNA5SP272 HGNC:HGNC:43172 +100873526 RNA5SP273 HGNC:HGNC:43173 +100873527 RNA5SP274 HGNC:HGNC:43174 +100873528 RNA5SP275 HGNC:HGNC:43175 +100873529 RNA5SP276 HGNC:HGNC:43176 +100873530 RNA5SP277 HGNC:HGNC:43177 +100873531 RNA5SP278 HGNC:HGNC:43178 +100873532 RNA5SP279 HGNC:HGNC:43179 +100873533 RNA5SP280 HGNC:HGNC:43180 +100873534 RNA5SP281 HGNC:HGNC:43181 +100873535 RNA5SP282 HGNC:HGNC:43182 +100873536 RNA5SP283 HGNC:HGNC:43183 +100873537 RNA5SP284 HGNC:HGNC:43184 +100873538 RNA5SP285 HGNC:HGNC:43185 +100873539 RNA5SP286 HGNC:HGNC:43186 +100873540 RNA5SP287 HGNC:HGNC:43187 +100873541 RNA5SP288 HGNC:HGNC:43188 +100873542 RNA5SP289 HGNC:HGNC:43189 +100873543 RNA5SP290 HGNC:HGNC:43190 +100873544 RNA5SP291 HGNC:HGNC:43191 +100873545 RNA5SP292 HGNC:HGNC:43192 +100873546 RNA5SP293 HGNC:HGNC:43193 +100873547 RNA5SP294 HGNC:HGNC:43194 +100873548 RNA5SP295 HGNC:HGNC:43195 +100873549 RNA5SP296 HGNC:HGNC:43196 +100873550 RNA5SP499 HGNC:HGNC:43399 +100873551 RNA5SP500 HGNC:HGNC:43400 +100873552 RNA5SP501 HGNC:HGNC:43401 +100873553 RNA5SP502 HGNC:HGNC:43402 +100873554 RNA5SP503 HGNC:HGNC:43403 +100873555 RNA5SP504 HGNC:HGNC:43404 +100873556 RNA5SP505 HGNC:HGNC:43405 +100873557 RNA5SP506 HGNC:HGNC:43406 +100873558 RNA5SP507 HGNC:HGNC:43407 +100873559 RNA5SP508 HGNC:HGNC:43408 +100873560 RNA5SP509 HGNC:HGNC:43409 +100873561 RNA5SP510 HGNC:HGNC:43410 +100873562 RNA5SP511 HGNC:HGNC:43411 +100873563 RNA5SP512 HGNC:HGNC:43412 +100873564 RNA5SP513 HGNC:HGNC:43413 +100873565 RNA5SP514 HGNC:HGNC:43414 +100873566 RNA5SP515 HGNC:HGNC:43415 +100873567 RNA5SP516 HGNC:HGNC:43416 +100873568 RNA5SP517 HGNC:HGNC:43417 +100873569 RNA5SP518 HGNC:HGNC:43418 +100873570 RNA5SP519 HGNC:HGNC:43419 +100873571 RNA5-8SP2 HGNC:HGNC:41956 +100873572 RNA5-8SP4 HGNC:HGNC:41958 +100873573 RNA5-8SP7 HGNC:HGNC:41962 +100873574 RNA5SP299 HGNC:HGNC:43199 +100873575 RNA5SP300 HGNC:HGNC:43200 +100873576 RNA5SP301 HGNC:HGNC:43201 +100873577 RNA5SP303 HGNC:HGNC:43203 +100873578 RNA5SP304 HGNC:HGNC:43204 +100873579 RNA5SP305 HGNC:HGNC:43205 +100873580 RNA5SP306 HGNC:HGNC:43206 +100873581 RNA5SP307 HGNC:HGNC:43207 +100873582 RNA5SP308 HGNC:HGNC:43208 +100873583 RNA5SP309 HGNC:HGNC:43209 +100873584 RNA5SP318 HGNC:HGNC:43218 +100873585 RNA5SP319 HGNC:HGNC:43219 +100873586 RNA5SP320 HGNC:HGNC:43220 +100873587 RNA5SP321 HGNC:HGNC:43221 +100873588 RNA5SP322 HGNC:HGNC:43222 +100873589 RNA5SP323 HGNC:HGNC:43223 +100873590 RNA5SP324 HGNC:HGNC:43224 +100873591 RNA5SP325 HGNC:HGNC:43225 +100873592 RNA5SP326 HGNC:HGNC:43226 +100873593 RNA5SP327 HGNC:HGNC:43227 +100873594 RNA5SP328 HGNC:HGNC:43228 +100873595 RNA5SP329 HGNC:HGNC:43229 +100873596 RNA5SP330 HGNC:HGNC:43230 +100873597 RNA5SP331 HGNC:HGNC:43231 +100873598 RNA5SP332 HGNC:HGNC:43232 +100873599 RNA5SP336 HGNC:HGNC:43236 +100873600 RNA5SP337 HGNC:HGNC:43237 +100873601 RNA5SP338 HGNC:HGNC:43238 +100873602 RNA5SP339 HGNC:HGNC:43239 +100873603 RNA5SP340 HGNC:HGNC:43240 +100873604 RNA5SP341 HGNC:HGNC:43241 +100873605 RNA5SP343 HGNC:HGNC:43243 +100873606 RNA5SP344 HGNC:HGNC:43244 +100873607 RNA5SP345 HGNC:HGNC:43245 +100873608 RNA5SP346 HGNC:HGNC:43246 +100873609 RNA5SP347 HGNC:HGNC:43247 +100873610 RNA5SP348 HGNC:HGNC:43248 +100873611 RNA5SP349 HGNC:HGNC:43249 +100873612 RNA5SP352 HGNC:HGNC:43252 +100873613 RNA5SP353 HGNC:HGNC:43253 +100873614 RNA5SP354 HGNC:HGNC:43254 +100873615 RNA5SP356 HGNC:HGNC:43256 +100873616 RNA5SP357 HGNC:HGNC:43257 +100873617 RNA5SP358 HGNC:HGNC:43258 +100873618 RNA5SP359 HGNC:HGNC:43259 +100873619 RNA5SP360 HGNC:HGNC:43260 +100873620 RNA5SP361 HGNC:HGNC:43261 +100873621 RNA5SP362 HGNC:HGNC:43262 +100873622 RNA5SP363 HGNC:HGNC:43263 +100873623 RNA5SP364 HGNC:HGNC:43264 +100873624 RNA5SP365 HGNC:HGNC:43265 +100873625 RNA5SP366 HGNC:HGNC:43266 +100873626 RNA5SP367 HGNC:HGNC:43267 +100873627 RNA5SP368 HGNC:HGNC:43268 +100873628 RNA5SP369 HGNC:HGNC:43269 +100873629 RNA5SP371 HGNC:HGNC:43271 +100873630 RNA5SP372 HGNC:HGNC:43272 +100873631 RNA5SP373 HGNC:HGNC:43273 +100873632 RNA5SP374 HGNC:HGNC:43274 +100873633 RNA5SP375 HGNC:HGNC:43275 +100873634 RNA5SP378 HGNC:HGNC:43278 +100873635 RNA5SP379 HGNC:HGNC:43279 +100873636 RNA5SP380 HGNC:HGNC:43280 +100873637 RNA5SP382 HGNC:HGNC:43282 +100873638 RNA5SP383 HGNC:HGNC:43283 +100873639 RNA5SP384 HGNC:HGNC:43284 +100873640 RNA5SP385 HGNC:HGNC:43285 +100873641 RNA5SP386 HGNC:HGNC:43286 +100873642 RNA5SP388 HGNC:HGNC:43288 +100873643 RNA5SP390 HGNC:HGNC:43290 +100873644 RNA5SP391 HGNC:HGNC:43291 +100873645 RNA5SP392 HGNC:HGNC:43292 +100873646 RNA5SP393 HGNC:HGNC:43293 +100873647 RNA5SP394 HGNC:HGNC:43294 +100873648 RNA5SP395 HGNC:HGNC:43295 +100873649 RNA5SP396 HGNC:HGNC:43296 +100873650 RNA5SP397 HGNC:HGNC:43297 +100873652 RNA5SP399 HGNC:HGNC:43299 +100873653 RNA5SP400 HGNC:HGNC:43300 +100873654 RNA5SP401 HGNC:HGNC:43301 +100873655 RNA5SP402 HGNC:HGNC:43302 +100873656 RNA5SP404 HGNC:HGNC:43304 +100873657 RNA5SP405 HGNC:HGNC:43305 +100873658 RNA5SP406 HGNC:HGNC:43306 +100873659 RNA5SP407 HGNC:HGNC:43307 +100873660 RNA5SP408 HGNC:HGNC:43308 +100873661 RNA5SP409 HGNC:HGNC:43309 +100873662 RNA5SP410 HGNC:HGNC:43310 +100873663 RNA5SP412 HGNC:HGNC:43312 +100873664 RNA5SP413 HGNC:HGNC:43313 +100873665 RNA5SP414 HGNC:HGNC:43314 +100873666 RNA5SP415 HGNC:HGNC:43315 +100873667 RNA5SP416 HGNC:HGNC:43316 +100873668 RNA5SP417 HGNC:HGNC:43317 +100873669 RNA5SP418 HGNC:HGNC:43318 +100873670 RNA5SP419 HGNC:HGNC:43319 +100873671 RNA5SP420 HGNC:HGNC:43320 +100873672 RNA5SP421 HGNC:HGNC:43321 +100873673 RNA5SP422 HGNC:HGNC:43322 +100873674 RNA5SP423 HGNC:HGNC:43323 +100873675 RNA5SP424 HGNC:HGNC:43324 +100873676 RNA5SP425 HGNC:HGNC:43325 +100873677 RNA5SP426 HGNC:HGNC:43326 +100873678 RNA5SP427 HGNC:HGNC:43327 +100873679 RNA5SP428 HGNC:HGNC:43328 +100873680 RNA5SP430 HGNC:HGNC:43330 +100873681 RNA5SP431 HGNC:HGNC:43331 +100873682 RNA5SP432 HGNC:HGNC:43332 +100873683 RNA5SP433 HGNC:HGNC:43333 +100873684 RNA5SP434 HGNC:HGNC:43334 +100873685 RNA5SP436 HGNC:HGNC:43336 +100873686 RNA5SP437 HGNC:HGNC:43337 +100873687 RNA5SP438 HGNC:HGNC:43338 +100873688 RNA5SP440 HGNC:HGNC:43340 +100873689 RNA5SP441 HGNC:HGNC:43341 +100873690 RNA5SP444 HGNC:HGNC:43344 +100873691 RNA5SP445 HGNC:HGNC:43345 +100873692 RNA5SP446 HGNC:HGNC:43346 +100873693 RNA5SP447 HGNC:HGNC:43347 +100873694 RNA5SP449 HGNC:HGNC:43349 +100873695 RNA5SP450 HGNC:HGNC:43350 +100873696 RNA5SP451 HGNC:HGNC:43351 +100873697 RNA5SP452 HGNC:HGNC:43352 +100873698 RNA5SP453 HGNC:HGNC:43353 +100873699 RNA5SP454 HGNC:HGNC:43354 +100873700 RNA5SP455 HGNC:HGNC:43355 +100873701 RNA5SP456 HGNC:HGNC:43356 +100873702 RNA5SP457 HGNC:HGNC:43357 +100873703 RNA5SP459 HGNC:HGNC:43359 +100873704 RNA5SP460 HGNC:HGNC:43360 +100873705 RNA5SP461 HGNC:HGNC:43361 +100873706 RNA5SP462 HGNC:HGNC:43362 +100873707 RNA5SP463 HGNC:HGNC:43363 +100873708 RNA5SP464 HGNC:HGNC:43364 +100873709 RNA5SP465 HGNC:HGNC:43365 +100873710 RNA5SP466 HGNC:HGNC:43366 +100873711 RNA5SP467 HGNC:HGNC:43367 +100873712 RNA5SP469 HGNC:HGNC:43369 +100873713 RNA5SP470 HGNC:HGNC:43370 +100873714 RNA5SP471 HGNC:HGNC:43371 +100873715 RNA5SP472 HGNC:HGNC:43372 +100873716 RNA5SP474 HGNC:HGNC:43374 +100873717 RNA5SP475 HGNC:HGNC:43375 +100873718 RNA5SP476 HGNC:HGNC:43376 +100873719 RNA5SP477 HGNC:HGNC:43377 +100873720 RNA5SP478 HGNC:HGNC:43378 +100873721 RNA5SP479 HGNC:HGNC:43379 +100873722 RNA5SP480 HGNC:HGNC:43380 +100873723 RNA5SP481 HGNC:HGNC:43381 +100873724 RNA5SP482 HGNC:HGNC:43382 +100873725 RNA5SP483 HGNC:HGNC:43383 +100873726 RNA5SP484 HGNC:HGNC:43384 +100873727 RNA5SP485 HGNC:HGNC:43385 +100873728 RNA5SP486 HGNC:HGNC:43386 +100873729 RNA5SP487 HGNC:HGNC:43387 +100873730 RNA5SP488 HGNC:HGNC:43388 +100873731 RNA5SP489 HGNC:HGNC:43389 +100873732 RNA5SP490 HGNC:HGNC:43390 +100873733 RNA5SP491 HGNC:HGNC:43391 +100873734 RNA5SP492 HGNC:HGNC:43392 +100873735 RNA5SP493 HGNC:HGNC:43393 +100873736 RNA5SP494 HGNC:HGNC:43394 +100873737 RNA5SP495 HGNC:HGNC:43395 +100873738 RNA5SP496 HGNC:HGNC:43396 +100873739 RNA5SP497 HGNC:HGNC:43397 +100873740 RNU6-31P HGNC:HGNC:34250 +100873741 RNU6-26P HGNC:HGNC:34252 +100873742 GOLGA2P4 HGNC:HGNC:38600 +100873743 NCSTNP1 HGNC:HGNC:39606 +100873744 PFN1P8 HGNC:HGNC:42986 +100873745 RNU6-10P HGNC:HGNC:34254 +100873746 RNU6-14P HGNC:HGNC:34258 +100873747 RNU6-30P HGNC:HGNC:34274 +100873748 RNU6-33P HGNC:HGNC:34277 +100873749 RNU6-34P HGNC:HGNC:34278 +100873750 RNU6-35P HGNC:HGNC:34279 +100873751 PHBP14 HGNC:HGNC:39293 +100873752 PHBP15 HGNC:HGNC:39294 +100873753 RNU6-16P HGNC:HGNC:34260 +100873754 RNU6-19P HGNC:HGNC:34263 +100873755 RNU6-23P HGNC:HGNC:34267 +100873756 RNU6-28P HGNC:HGNC:34272 +100873757 RNU6-36P HGNC:HGNC:34280 +100873758 RNU6-39P HGNC:HGNC:34283 +100873759 RNU6-45P HGNC:HGNC:34289 +100873760 RNU6-46P HGNC:HGNC:34290 +100873761 RNU6-52P HGNC:HGNC:42542 +100873762 RNU6-53P HGNC:HGNC:42543 +100873763 RNU6-55P HGNC:HGNC:42545 +100873764 RNU6-56P HGNC:HGNC:42546 +100873765 RNU6-57P HGNC:HGNC:42547 +100873766 RNU6-58P HGNC:HGNC:42548 +100873767 RNU6-59P HGNC:HGNC:42549 +100873768 RNU6-63P HGNC:HGNC:42553 +100873769 RNU6-64P HGNC:HGNC:42554 +100873770 RNU6-66P HGNC:HGNC:42556 +100873771 RNU6-67P HGNC:HGNC:42557 +100873772 RNU6-68P HGNC:HGNC:42558 +100873773 RNU6-69P HGNC:HGNC:42559 +100873774 RNU6-71P HGNC:HGNC:42561 +100873775 RNU6-72P HGNC:HGNC:42562 +100873776 RNU6-75P HGNC:HGNC:42565 +100873777 RNU6-76P HGNC:HGNC:42566 +100873778 RNU6-78P HGNC:HGNC:42568 +100873779 RNU6-79P HGNC:HGNC:42569 +100873780 RNU6-81P HGNC:HGNC:42571 +100873781 RNU6-82P HGNC:HGNC:42572 +100873782 RNU6-83P HGNC:HGNC:42573 +100873783 UBBP5 HGNC:HGNC:42645 +100873784 PFN1P11 HGNC:HGNC:42994 +100873785 SNX2P2 HGNC:HGNC:41515 +100873786 TMSB10P2 HGNC:HGNC:41950 +100873787 GPM6BP3 HGNC:HGNC:38783 +100873788 SNX18P27 HGNC:HGNC:39635 +100873789 AK3P6 HGNC:HGNC:39065 +100873790 FHP1 HGNC:HGNC:39442 +100873791 CHEK2P3 HGNC:HGNC:43579 +100873792 CBX3P4 HGNC:HGNC:42876 +100873793 PHF2P2 HGNC:HGNC:38808 +100873794 ASNSP5 HGNC:HGNC:39401 +100873795 WDR95P HGNC:HGNC:42637 +100873796 RPL35P9 HGNC:HGNC:39402 +100873797 RPSAP64 HGNC:HGNC:39642 +100873798 RPS21P8 HGNC:HGNC:39705 +100873799 ZNF90P3 HGNC:HGNC:39882 +100873800 RNY4P22 HGNC:HGNC:42472 +100873801 RNY4P23 HGNC:HGNC:42473 +100873802 RNY1P1 HGNC:HGNC:42478 +100873803 RNY1P3 HGNC:HGNC:42480 +100873804 RNY1P4 HGNC:HGNC:42481 +100873805 RNY1P6 HGNC:HGNC:42483 +100873806 RNY1P7 HGNC:HGNC:42484 +100873807 RNY1P8 HGNC:HGNC:42485 +100873808 RNY3P4 HGNC:HGNC:42488 +100873809 RNY3P5 HGNC:HGNC:42489 +100873810 RNY3P6 HGNC:HGNC:42490 +100873811 ZNF877P HGNC:HGNC:38697 +100873812 CFL1P8 HGNC:HGNC:39960 +100873813 HLFP1 HGNC:HGNC:41922 +100873814 RNU1-17P HGNC:HGNC:41943 +100873815 RNU1-18P HGNC:HGNC:41944 +100873816 RNU1-20P HGNC:HGNC:41946 +100873817 RPL7AP73 HGNC:HGNC:41968 +100873818 RPS3AP52 HGNC:HGNC:42004 +100873819 RNY4P26 HGNC:HGNC:42476 +100873820 RNY3P10 HGNC:HGNC:42494 +100873821 RNY4P27 HGNC:HGNC:42495 +100873822 RNY4P28 HGNC:HGNC:42496 +100873823 RNY4P29 HGNC:HGNC:42497 +100873824 RNU2-7P HGNC:HGNC:42505 +100873825 RNU2-6P HGNC:HGNC:42506 +100873826 RNU5F-2P HGNC:HGNC:42510 +100873827 RNU5E-2P HGNC:HGNC:42511 +100873828 RNU5E-3P HGNC:HGNC:42512 +100873829 RNU5E-4P HGNC:HGNC:42513 +100873830 RNU5A-2P HGNC:HGNC:42515 +100873831 RNU5A-3P HGNC:HGNC:42519 +100873832 RNU5E-6P HGNC:HGNC:42522 +100873833 RNU5F-6P HGNC:HGNC:42523 +100873834 RNU5F-7P HGNC:HGNC:42524 +100873835 RNU5A-5P HGNC:HGNC:42525 +100873836 RNU5E-7P HGNC:HGNC:42526 +100873837 RNU5E-8P HGNC:HGNC:42528 +100873838 RNU5A-8P HGNC:HGNC:42530 +100873839 RNU5F-8P HGNC:HGNC:42531 +100873840 RNU5E-9P HGNC:HGNC:42532 +100873841 RNU5D-2P HGNC:HGNC:42534 +100873842 RNU7-87P HGNC:HGNC:42616 +100873843 RNU7-88P HGNC:HGNC:42617 +100873844 RNU7-89P HGNC:HGNC:42618 +100873845 RN7SKP1 HGNC:HGNC:42619 +100873846 RN7SKP2 HGNC:HGNC:42620 +100873847 RN7SKP3 HGNC:HGNC:42621 +100873848 RN7SKP4 HGNC:HGNC:42622 +100873849 RN7SKP5 HGNC:HGNC:42623 +100873850 RN7SKP6 HGNC:HGNC:42624 +100873851 RN7SKP7 HGNC:HGNC:42625 +100873852 RN7SKP8 HGNC:HGNC:42626 +100873853 RN7SKP9 HGNC:HGNC:42627 +100873854 MOB1AP2 HGNC:HGNC:42639 +100873855 RPL36P19 HGNC:HGNC:42648 +100873856 SNORD116-30 HGNC:HGNC:42797|Ensembl:ENSG00000252277 +100873857 SNORD115-46 HGNC:HGNC:42798|Ensembl:ENSG00000276844 +100873858 SDAD1P3 HGNC:HGNC:39260 +100873859 RPL18AP17 HGNC:HGNC:39850 +100873860 RNU1-16P HGNC:HGNC:39890 +100873861 RNU1-19P HGNC:HGNC:41945 +100873862 RNU1-21P HGNC:HGNC:41947 +100873863 RNU1-22P HGNC:HGNC:41963 +100873864 LAP3P1 HGNC:HGNC:42364 +100873865 RNU1-24P HGNC:HGNC:42504 +100873866 RNU5F-3P HGNC:HGNC:42514 +100873867 RNU5F-4P HGNC:HGNC:42516 +100873868 RNU5F-5P HGNC:HGNC:42518 +100873869 RNU5E-5P HGNC:HGNC:42520 +100873870 RNU5A-4P HGNC:HGNC:42521 +100873871 RNU5A-6P HGNC:HGNC:42527 +100873872 RNU5A-7P HGNC:HGNC:42529 +100873873 RN7SKP10 HGNC:HGNC:42628 +100873874 MOB1AP1 HGNC:HGNC:42638 +100873875 PSPC1P2 HGNC:HGNC:42643 +100873876 TRV-CAC10-1 HGNC:HGNC:38576 +100873877 TMSB4XP3 HGNC:HGNC:38587 +100873878 MORF4L1P6 HGNC:HGNC:39258 +100873879 HMGB3P9 HGNC:HGNC:39301 +100873880 TMEM97P1 HGNC:HGNC:39640 +100873881 GRAMD4P2 HGNC:HGNC:39654 +100873882 ANKRD26P4 HGNC:HGNC:39690 +100873883 FGFR1OP2P1 HGNC:HGNC:39706 +100873884 SNX3P1X HGNC:HGNC:41516 +100873885 SNX3P1Y HGNC:HGNC:41517 +100873886 SCAND3P1 HGNC:HGNC:42037 +100873887 PGAM1P3 HGNC:HGNC:42450 +100873888 RNU5E-10P HGNC:HGNC:42533 +100873889 RNU4ATAC2P HGNC:HGNC:39003 +100873890 HMGB3P4 HGNC:HGNC:39104 +100873891 HMGB1P23 HGNC:HGNC:39114 +100873892 HMGB1P29 HGNC:HGNC:39120 +100873893 HMGB1P30 HGNC:HGNC:39121 +100873894 HMGB1P31 HGNC:HGNC:39122 +100873895 HMGB1P38 HGNC:HGNC:39185 +100873896 HMGB1P41 HGNC:HGNC:39188 +100873897 HMGB1P47 HGNC:HGNC:39280 +100873898 HMGB3P12 HGNC:HGNC:39304 +100873899 HMGB3P14 HGNC:HGNC:39306 +100873900 HMGB3P16 HGNC:HGNC:39308 +100873901 HMGB3P21 HGNC:HGNC:39313 +100873902 GK-AS1 HGNC:HGNC:40255 +100873903 HSPA9P2 HGNC:HGNC:31733 +100873904 MYB-AS1 HGNC:HGNC:37457 +100873905 HMGB1P33 HGNC:HGNC:39124 +100873906 HMGB1P42 HGNC:HGNC:39189 +100873907 ORAOV1P1 HGNC:HGNC:39203 +100873908 HMGB3P25 HGNC:HGNC:39317 +100873909 DUTP2 HGNC:HGNC:39515 +100873910 DUTP4 HGNC:HGNC:39517 +100873911 DUTP5 HGNC:HGNC:39518 +100873912 DUTP6 HGNC:HGNC:39519 +100873913 DUTP7 HGNC:HGNC:39520 +100873914 DUTP8 HGNC:HGNC:39521 +100873916 DMD-AS3 HGNC:HGNC:40185 +100873917 LPP-AS1 HGNC:HGNC:40346|Ensembl:ENSG00000224563 +100873918 MME-AS1 HGNC:HGNC:40376 +100873919 NDP-AS1 HGNC:HGNC:40395 +100873920 NHS-AS1 HGNC:HGNC:40403 +100873921 SYP-AS1 HGNC:HGNC:40571|Ensembl:ENSG00000237341 +100873922 ZFX-AS1 HGNC:HGNC:40617|Ensembl:ENSG00000234230 +100873923 HYI-AS1 HGNC:HGNC:41173 +100873924 HLX-AS1 HGNC:HGNC:42509|Ensembl:ENSG00000257551 +100873926 TAB3-AS2 HGNC:HGNC:40013 +100873928 CASK-AS1 HGNC:HGNC:40126 +100873930 DLG3-AS1 HGNC:HGNC:40182|Ensembl:ENSG00000231651 +100873931 DLX6-AS2 HGNC:HGNC:40183 +100873932 DPYD-AS1 HGNC:HGNC:40195|Ensembl:ENSG00000232878 +100873933 DPYD-AS2 HGNC:HGNC:40196|Ensembl:ENSG00000235777 +100873934 ETV5-AS1 HGNC:HGNC:40222 +100873935 MTOR-AS1 HGNC:HGNC:40242|Ensembl:ENSG00000225602 +100873937 GRM7-AS1 HGNC:HGNC:40267|Ensembl:ENSG00000236202 +100873938 GYG2-AS1 HGNC:HGNC:40270 +100873939 LNX1-AS1 HGNC:HGNC:40345|Ensembl:ENSG00000250930 +100873940 MYLK-AS2 HGNC:HGNC:40387|Ensembl:ENSG00000250174 +100873941 OPA1-AS1 HGNC:HGNC:40421|Ensembl:ENSG00000224855 +100873942 PHEX-AS1 HGNC:HGNC:40445|Ensembl:ENSG00000224204 +100873943 PLS1-AS1 HGNC:HGNC:40451 +100873944 PRKX-AS1 HGNC:HGNC:40479|Ensembl:ENSG00000236188 +100873945 HLTF-AS1 HGNC:HGNC:40554|Ensembl:ENSG00000239718 +100873946 VAV3-AS1 HGNC:HGNC:40608|Ensembl:ENSG00000230489 +100873947 LMLN-AS1 HGNC:HGNC:40738|Ensembl:ENSG00000232832 +100873948 NREP-AS1 HGNC:HGNC:40780|Ensembl:ENSG00000250095 +100873949 IPO9-AS1 HGNC:HGNC:40892|Ensembl:ENSG00000231871 +100873950 ZIC4-AS1 HGNC:HGNC:40920 +100873951 MLIP-AS1 HGNC:HGNC:40963 +100873952 SZT2-AS1 HGNC:HGNC:41225 +100873953 WWC3-AS1 HGNC:HGNC:41236 +100873954 SNRK-AS1 HGNC:HGNC:41269 +100873955 LNX1-AS2 HGNC:HGNC:41450 +100873956 EAF1-AS1 HGNC:HGNC:42328 +100873957 FABP5P14 HGNC:HGNC:31065 +100873958 FABP5P15 HGNC:HGNC:31071 +100873960 FTLP19 HGNC:HGNC:37969 +100873961 TRN-GTT21-1 HGNC:HGNC:38584 +100873962 LINC00278 HGNC:HGNC:38712|Ensembl:ENSG00000231535 +100873963 LINC00279 HGNC:HGNC:38724|Ensembl:ENSG00000232348 +100873964 LINC00280 HGNC:HGNC:38803|Ensembl:ENSG00000229643 +100873965 MED4-AS1 HGNC:HGNC:39213|Ensembl:ENSG00000229111 +100873966 SPATA2P1 HGNC:HGNC:39446 +100873967 LSP1P2 HGNC:HGNC:39717 +100873969 GPC5-AS1 HGNC:HGNC:39886|Ensembl:ENSG00000235984 +100873970 GPC5-AS2 HGNC:HGNC:39887 +100873972 GPC6-AS1 HGNC:HGNC:39909|Ensembl:ENSG00000236520 +100873973 GPC6-AS2 HGNC:HGNC:39910 +100873974 KCNC4-AS1 HGNC:HGNC:39958 +100873975 CNTN4-AS1 HGNC:HGNC:39985 +100873976 CNTN4-AS2 HGNC:HGNC:39986|Ensembl:ENSG00000227588 +100873977 RBMS3-AS1 HGNC:HGNC:39987|Ensembl:ENSG00000235593 +100873978 RBMS3-AS2 HGNC:HGNC:39988 +100873979 RBMS3-AS3 HGNC:HGNC:39989 +100873980 RERG-AS1 HGNC:HGNC:39990|Ensembl:ENSG00000255660 +100873981 ANO1-AS1 HGNC:HGNC:40016 +100873982 ABCC5-AS1 HGNC:HGNC:40055|Ensembl:ENSG00000223882 +100873983 MAGI1-AS1 HGNC:HGNC:40091|Ensembl:ENSG00000240175 +100873984 CHRM3-AS1 HGNC:HGNC:40150|Ensembl:ENSG00000234601 +100873985 MED14OS HGNC:HGNC:40162 +100873986 FGF12-AS1 HGNC:HGNC:40234|Ensembl:ENSG00000231383 +100873987 FGF12-AS2 HGNC:HGNC:40235 +100873988 FGF12-AS3 HGNC:HGNC:40236 +100873989 GRM5-AS1 HGNC:HGNC:40265|Ensembl:ENSG00000255082 +100873990 HCFC1-AS1 HGNC:HGNC:40273 +100873991 IGBP1-AS1 HGNC:HGNC:40295 +100873992 ITGB5-AS1 HGNC:HGNC:40309 +100873993 ITIH4-AS1 HGNC:HGNC:40310|Ensembl:ENSG00000239799 +100873994 ITPKB-AS1 HGNC:HGNC:40312 +100873995 KCND3-AS1 HGNC:HGNC:40317|Ensembl:ENSG00000237556 +100873997 KCNQ5-AS1 HGNC:HGNC:40323|Ensembl:ENSG00000229154 +100873998 MEIS1-AS2 HGNC:HGNC:40370|Ensembl:ENSG00000230749 +100874001 NCBP2-AS1 HGNC:HGNC:40392 +100874002 OXCT1-AS1 HGNC:HGNC:40423|Ensembl:ENSG00000248668 +100874003 PLCL2-AS1 HGNC:HGNC:40449 +100874004 PPEF1-AS1 HGNC:HGNC:40463 +100874005 SIAH2-AS1 HGNC:HGNC:40526 +100874006 TTC3-AS1 HGNC:HGNC:40595 +100874007 VIPR1-AS1 HGNC:HGNC:40610 +100874008 WNT5A-AS1 HGNC:HGNC:40616 +100874009 BIRC6-AS1 HGNC:HGNC:40641 +100874010 NLGN1-AS1 HGNC:HGNC:40676|Ensembl:ENSG00000228213 +100874011 XIRP2-AS1 HGNC:HGNC:40679 +100874012 NAV2-AS5 HGNC:HGNC:40740|Ensembl:ENSG00000255043 +100874013 NAV2-AS3 HGNC:HGNC:40742 +100874014 NAV2-AS2 HGNC:HGNC:40743|Ensembl:ENSG00000254453 +100874015 NAV2-AS1 HGNC:HGNC:40744 +100874016 SYNPR-AS1 HGNC:HGNC:40774|Ensembl:ENSG00000241359 +100874018 EPN2-AS1 HGNC:HGNC:40849|Ensembl:ENSG00000235397 +100874019 KLHL6-AS1 HGNC:HGNC:40850|Ensembl:ENSG00000242522 +100874020 MAGI2-AS1 HGNC:HGNC:40860 +100874021 MAGI2-AS2 HGNC:HGNC:40861|Ensembl:ENSG00000226978 +100874022 ATG10-AS1 HGNC:HGNC:40914 +100874023 WDFY3-AS1 HGNC:HGNC:40935 +100874024 TRPC7-AS1 HGNC:HGNC:40936 +100874025 GFOD1-AS1 HGNC:HGNC:40956 +100874027 TPRG1-AS2 HGNC:HGNC:41062|Ensembl:ENSG00000230115 +100874028 SGO1-AS1 HGNC:HGNC:41081|Ensembl:ENSG00000231304 +100874029 CFAP44-AS1 HGNC:HGNC:41113|Ensembl:ENSG00000243849 +100874030 SIDT1-AS1 HGNC:HGNC:41126 +100874031 AGBL5-AS1 HGNC:HGNC:41133|Ensembl:ENSG00000231636 +100874032 PRRT3-AS1 HGNC:HGNC:41151|Ensembl:ENSG00000230082 +100874033 SPIN4-AS1 HGNC:HGNC:41177 +100874034 UBXN7-AS1 HGNC:HGNC:41227 +100874035 PLCH1-AS1 HGNC:HGNC:41231 +100874036 PLCH1-AS2 HGNC:HGNC:41232|Ensembl:ENSG00000242925 +100874037 CADM2-AS2 HGNC:HGNC:41247|Ensembl:ENSG00000241648 +100874038 CADM2-AS1 HGNC:HGNC:41248 +100874039 THOC7-AS1 HGNC:HGNC:41249|Ensembl:ENSG00000240549 +100874040 PEX5L-AS1 HGNC:HGNC:41251 +100874041 MACC1-AS1 HGNC:HGNC:41257|Ensembl:ENSG00000228598 +100874042 HM13-AS1 HGNC:HGNC:41940|Ensembl:ENSG00000230613 +100874043 TPRG1-AS1 HGNC:HGNC:42391|Ensembl:ENSG00000234076 +100874044 HHATL-AS1 HGNC:HGNC:42439 +100874045 MEAF6P1 HGNC:HGNC:42660 +100874047 LINC00499 HGNC:HGNC:43436|Ensembl:ENSG00000251372 +100874048 DGUOK-AS1 HGNC:HGNC:43441|Ensembl:ENSG00000237883 +100874049 LINC00505 HGNC:HGNC:43556 +100874051 LZTS1-AS1 HGNC:HGNC:43630|Ensembl:ENSG00000253733 +100874052 LINC00534 HGNC:HGNC:43643|Ensembl:ENSG00000253394 +100874053 JRKL-AS1 HGNC:HGNC:43670 +100874054 FALEC MIM:616092|HGNC:HGNC:43713|Ensembl:ENSG00000228126 +100874055 LINC00570 HGNC:HGNC:43717|Ensembl:ENSG00000224177 +100874056 NLGN4Y-AS1 HGNC:HGNC:38793|Ensembl:ENSG00000228787 +100874057 LINC00283 HGNC:HGNC:38809 +100874058 COX10-AS1 HGNC:HGNC:38873|Ensembl:ENSG00000236088 +100874059 LINC00297 HGNC:HGNC:39210|Ensembl:ENSG00000224329 +100874060 SPATA20P1 HGNC:HGNC:39636 +100874061 WASF3-AS1 HGNC:HGNC:39841 +100874063 CLYBL-AS2 HGNC:HGNC:39894|Ensembl:ENSG00000227659 +100874064 PCDH9-AS2 HGNC:HGNC:39896|Ensembl:ENSG00000228842 +100874065 PCDH9-AS1 HGNC:HGNC:39897 +100874066 LATS2-AS1 HGNC:HGNC:39912 +100874067 MYO16-AS2 HGNC:HGNC:39914 +100874068 GRTP1-AS1 HGNC:HGNC:39917 +100874069 STK24-AS1 HGNC:HGNC:39935 +100874070 USP12-AS1 HGNC:HGNC:39961 +100874071 USP12-AS2 HGNC:HGNC:39962 +100874072 SMAD9-IT1 HGNC:HGNC:39963 +100874073 FREM2-AS1 HGNC:HGNC:39964 +100874074 DLEU7-AS1 HGNC:HGNC:39966|Ensembl:ENSG00000237152 +100874075 ARAP1-AS1 HGNC:HGNC:39993 +100874077 ATP1B3-AS1 HGNC:HGNC:40088 +100874078 EIF1AX-AS1 HGNC:HGNC:40208|Ensembl:ENSG00000225037 +100874079 LINC01840 HGNC:HGNC:40209|Ensembl:ENSG00000230215 +100874080 FARP1-AS1 HGNC:HGNC:40229 +100874081 FGF14-AS1 HGNC:HGNC:40237|Ensembl:ENSG00000234445 +100874082 HTR2A-AS1 HGNC:HGNC:40289|Ensembl:ENSG00000224517 +100874083 KCNAB1-AS2 HGNC:HGNC:40315|Ensembl:ENSG00000240596 +100874084 KCNAB1-AS1 HGNC:HGNC:40316|Ensembl:ENSG00000242370 +100874085 NUCB1-AS1 HGNC:HGNC:40419|Ensembl:ENSG00000235191 +100874086 PCDH9-AS3 HGNC:HGNC:40427|Ensembl:ENSG00000225263 +100874087 PCDH9-AS4 HGNC:HGNC:40428|Ensembl:ENSG00000233840 +100874088 PCYT1B-AS1 HGNC:HGNC:40431|Ensembl:ENSG00000236836 +100874089 RUVBL1-AS1 HGNC:HGNC:40514|Ensembl:ENSG00000239608 +100874090 SLC6A1-AS1 HGNC:HGNC:40546|Ensembl:ENSG00000232287 +100874091 TM4SF1-AS1 HGNC:HGNC:40587|Ensembl:ENSG00000240541 +100874092 UBE2E1-AS1 HGNC:HGNC:40598|Ensembl:ENSG00000223791 +100874093 BRWD1-AS1 HGNC:HGNC:40614|Ensembl:ENSG00000238141 +100874094 ZNF197-AS1 HGNC:HGNC:40620|Ensembl:ENSG00000233509 +100874095 ADIPOQ-AS1 HGNC:HGNC:40648|Ensembl:ENSG00000226482 +100874096 DOCK9-AS1 HGNC:HGNC:40672|Ensembl:ENSG00000229918 +100874097 UBE2Q1-AS1 HGNC:HGNC:40722|Ensembl:ENSG00000229780 +100874098 ARPP21-AS1 HGNC:HGNC:40785 +100874100 STEAP2-AS1 HGNC:HGNC:40820|Ensembl:ENSG00000227646 +100874101 HDAC11-AS1 HGNC:HGNC:40868|Ensembl:ENSG00000244502 +100874102 HS6ST2-AS1 HGNC:HGNC:40870|Ensembl:ENSG00000235849 +100874103 SRGAP3-AS1 HGNC:HGNC:40898 +100874104 PLSCR5-AS1 HGNC:HGNC:40907 +100874106 MTUS2-AS2 HGNC:HGNC:40923 +100874107 MTUS2-AS1 HGNC:HGNC:40924 +100874108 A2ML1-AS1 HGNC:HGNC:41022 +100874109 CNOT10-AS1 HGNC:HGNC:41031 +100874110 GLYCTK-AS1 HGNC:HGNC:41043 +100874111 STEAP3-AS1 HGNC:HGNC:41053|Ensembl:ENSG00000229867 +100874112 CCDC39-AS1 HGNC:HGNC:41089 +100874113 YEATS2-AS1 HGNC:HGNC:41101 +100874114 CCDC13-AS1 HGNC:HGNC:41142|Ensembl:ENSG00000173811 +100874115 PLCXD2-AS1 HGNC:HGNC:41145 +100874116 EGFLAM-AS3 HGNC:HGNC:41167 +100874117 EGFLAM-AS1 HGNC:HGNC:41169 +100874118 INTS6L-AS1 HGNC:HGNC:41180|Ensembl:ENSG00000225235 +100874119 TCEAL3-AS1 HGNC:HGNC:41191 +100874120 ZNF630-AS1 HGNC:HGNC:41215|Ensembl:ENSG00000277541 +100874121 FRMPD4-AS1 HGNC:HGNC:41222 +100874122 FRMPD3-AS1 HGNC:HGNC:41239|Ensembl:ENSG00000227610 +100874123 ZNRF3-AS1 HGNC:HGNC:41927|Ensembl:ENSG00000177993 +100874124 RPLP1P13 HGNC:HGNC:41973 +100874126 LINC00331 HGNC:HGNC:42048 +100874127 LINC00332 HGNC:HGNC:42049|Ensembl:ENSG00000230710 +100874128 LINC00333 HGNC:HGNC:42050 +100874129 ENOX1-AS1 HGNC:HGNC:42396 +100874130 ENOX1-AS2 HGNC:HGNC:42397 +100874131 ZBTB20-AS4 HGNC:HGNC:42423|Ensembl:ENSG00000242767 +100874135 LINC00349 HGNC:HGNC:42667 +100874136 LINC00350 HGNC:HGNC:42668 +100874137 LINC00351 HGNC:HGNC:42669|Ensembl:ENSG00000226317 +100874138 LINC00352 HGNC:HGNC:42670 +100874139 LINC00353 HGNC:HGNC:42671 +100874143 LINC00358 HGNC:HGNC:42678|Ensembl:ENSG00000229578 +100874144 LINC00362 HGNC:HGNC:42682 +100874145 LINC00364 HGNC:HGNC:42686|Ensembl:ENSG00000230040 +100874146 LINC00365 HGNC:HGNC:42687|Ensembl:ENSG00000224511 +100874147 LINC00366 HGNC:HGNC:42688 +100874150 LINC00379 HGNC:HGNC:42705 +100874151 LINC00381 HGNC:HGNC:42708|Ensembl:ENSG00000226240 +100874152 LINC00387 HGNC:HGNC:42715 +100874153 LINC00388 HGNC:HGNC:42716 +100874154 LINC00391 HGNC:HGNC:42719 +100874155 LINC00392 HGNC:HGNC:42720 +100874156 LINC00393 HGNC:HGNC:42721 +100874157 LINC00395 HGNC:HGNC:42723|Ensembl:ENSG00000231061 +100874158 LINC00398 HGNC:HGNC:42727|Ensembl:ENSG00000237879 +100874159 LINC00400 HGNC:HGNC:42729 +100874160 LINC00404 HGNC:HGNC:42734 +100874161 LINC00411 HGNC:HGNC:42744 +100874164 LINC00417 - +100874167 LINC00423 HGNC:HGNC:42758 +100874168 LINC00433 HGNC:HGNC:42768 +100874169 LINC00434 HGNC:HGNC:42769 +100874172 LINC00440 HGNC:HGNC:42777 +100874173 LINC00443 HGNC:HGNC:42780|Ensembl:ENSG00000230156 +100874175 LINC00446 HGNC:HGNC:42783 +100874176 LINC00448 HGNC:HGNC:42785 +100874178 LINC00454 HGNC:HGNC:42802 +100874179 LINC00457 HGNC:HGNC:42805|Ensembl:ENSG00000225179 +100874180 LINC00459 HGNC:HGNC:42808 +100874182 LINC00424 HGNC:HGNC:42815|Ensembl:ENSG00000226722 +100874183 NCOR1P3 HGNC:HGNC:42996 +100874184 LINC00502 HGNC:HGNC:43442 +100874185 FRMD6-AS2 HGNC:HGNC:43637|Ensembl:ENSG00000258537 +100874186 PLCB2-AS1 HGNC:HGNC:43662 +100874187 LINC00559 HGNC:HGNC:43703|Ensembl:ENSG00000261446 +100874188 LINC00571 HGNC:HGNC:43721|Ensembl:ENSG00000223685 +100874189 NKX2-2-AS1 HGNC:HGNC:37154 +100874190 SAMSN1-AS1 HGNC:HGNC:39599|Ensembl:ENSG00000223662 +100874191 RANP2 HGNC:HGNC:39857 +100874192 RANP7 HGNC:HGNC:39862 +100874193 RANP9 HGNC:HGNC:39864 +100874194 CLDN10-AS1 HGNC:HGNC:39907|Ensembl:ENSG00000223392 +100874195 DIAPH3-AS1 HGNC:HGNC:39915|Ensembl:ENSG00000227528 +100874196 DIAPH3-AS2 HGNC:HGNC:39916|Ensembl:ENSG00000223815 +100874197 EFCAB6-AS1 HGNC:HGNC:39999 +100874198 SHANK2-AS1 HGNC:HGNC:40014|Ensembl:ENSG00000226627 +100874199 SHANK2-AS2 HGNC:HGNC:40015 +100874200 ARHGEF3-AS1 HGNC:HGNC:40083|Ensembl:ENSG00000240198 +100874201 B4GALT4-AS1 HGNC:HGNC:40090|Ensembl:ENSG00000240254 +100874202 MIS18A-AS1 HGNC:HGNC:40106 +100874203 COL4A2-AS1 HGNC:HGNC:40156|Ensembl:ENSG00000232814 +100874204 ALDH1L1-AS1 HGNC:HGNC:40244|Ensembl:ENSG00000250218 +100874205 ATP11A-AS1 HGNC:HGNC:40645|Ensembl:ENSG00000232684 +100874206 OSBPL10-AS1 HGNC:HGNC:40767|Ensembl:ENSG00000232490 +100874207 ST3GAL6-AS1 HGNC:HGNC:40828|Ensembl:ENSG00000239445 +100874208 NDFIP2-AS1 HGNC:HGNC:40844|Ensembl:ENSG00000232132 +100874210 ZMYND10-AS1 HGNC:HGNC:40890 +100874211 MID1IP1-AS1 HGNC:HGNC:40932 +100874212 MYCBP2-AS1 HGNC:HGNC:41023|Ensembl:ENSG00000236051 +100874213 MYCBP2-AS2 HGNC:HGNC:41024 +100874214 TM4SF19-AS1 HGNC:HGNC:41085|Ensembl:ENSG00000235897 +100874216 ZNF385D-AS1 HGNC:HGNC:41136|Ensembl:ENSG00000225542 +100874217 TBL1XR1-AS1 HGNC:HGNC:41243 +100874218 ATP13A5-AS1 HGNC:HGNC:41281 +100874219 TMEM212-AS1 HGNC:HGNC:41939|Ensembl:ENSG00000234717 +100874220 PCNPP4 HGNC:HGNC:41976 +100874221 ZNF385D-AS2 HGNC:HGNC:42420|Ensembl:ENSG00000223351 +100874222 RNF219-AS1 HGNC:HGNC:42700|Ensembl:ENSG00000234377 +100874223 FTOP1 HGNC:HGNC:43759 +100874224 KRTAP10-13P HGNC:HGNC:34213 +100874225 RPP40P1 HGNC:HGNC:39769 +100874226 ARHGEF7-AS1 HGNC:HGNC:39816 +100874227 RANP3 HGNC:HGNC:39858 +100874229 DCUN1D2-AS HGNC:HGNC:39889 +100874231 SPATA13-AS1 HGNC:HGNC:39905|Ensembl:ENSG00000227213 +100874232 C1QTNF9-AS1 HGNC:HGNC:39906 +100874233 ARHGEF19-AS1 HGNC:HGNC:39996 +100874234 CACNA1C-AS4 HGNC:HGNC:40116|Ensembl:ENSG00000256025 +100874235 CACNA1C-AS2 HGNC:HGNC:40118|Ensembl:ENSG00000256271 +100874236 COL18A1-AS2 HGNC:HGNC:40155|Ensembl:ENSG00000224574 +100874237 CACNA2D3-AS1 HGNC:HGNC:40702|Ensembl:ENSG00000243715 +100874238 ARHGEF7-AS2 HGNC:HGNC:40717|Ensembl:ENSG00000235875 +100874239 ARHGAP26-AS1 HGNC:HGNC:40792|Ensembl:ENSG00000226272 +100874241 STARD13-AS HGNC:HGNC:40873|Ensembl:ENSG00000236581 +100874242 PRICKLE2-AS2 HGNC:HGNC:40917 +100874243 PRICKLE2-AS3 HGNC:HGNC:40918|Ensembl:ENSG00000226017 +100874244 NAALADL2-AS2 HGNC:HGNC:41015 +100874245 NAALADL2-AS1 HGNC:HGNC:41016 +100874246 ARHGAP31-AS1 HGNC:HGNC:41235|Ensembl:ENSG00000241155 +100874247 ANKRD33B-AS1 HGNC:HGNC:41298 +100874248 USP24P1 HGNC:HGNC:42014 +100874249 DENND5B-AS1 HGNC:HGNC:42517|Ensembl:ENSG00000255867 +100874250 KIRREL3-AS1 HGNC:HGNC:42655 +100874251 KIRREL3-AS2 HGNC:HGNC:42656|Ensembl:ENSG00000254960 +100874252 USP32P4 HGNC:HGNC:43577 +100874253 LINC00853 HGNC:HGNC:43716|Ensembl:ENSG00000224805 +100874254 JTBP1 HGNC:HGNC:39180 +100874255 RNASEH2B-AS1 HGNC:HGNC:39967 +100874256 TNR-IT1 HGNC:HGNC:41391 +100874257 MTAPP1 HGNC:HGNC:42442 +100874258 SCGB1D5P HGNC:HGNC:42735 +100874259 SLC25A30-AS1 HGNC:HGNC:42795|Ensembl:ENSG00000251015 +100874260 UBE2CP5 HGNC:HGNC:43554 +100874261 LINC00854 HGNC:HGNC:43658|Ensembl:ENSG00000236383|Vega:OTTHUMG00000132641 +100874262 UBE2D3P3 HGNC:HGNC:39011 +100874263 AKT3-IT1 HGNC:HGNC:41304 +100874264 AOAH-IT1 HGNC:HGNC:41307|Ensembl:ENSG00000230539 +100874266 LYST-AS1 HGNC:HGNC:41320 +100874267 DPYD-IT1 HGNC:HGNC:41326 +100874268 E2F3-IT1 HGNC:HGNC:41329 +100874269 AFF2-IT1 HGNC:HGNC:41334 +100874270 HAO2-IT1 HGNC:HGNC:41342|Ensembl:ENSG00000230921 +100874272 KLF7-IT1 HGNC:HGNC:41355 +100874273 TGFA-IT1 HGNC:HGNC:41389|Ensembl:ENSG00000224606 +100874274 THRB-IT1 HGNC:HGNC:41390 +100874275 LINC01216 HGNC:HGNC:41418|Ensembl:ENSG00000250223 +100874276 LINC01217 HGNC:HGNC:41419 +100874278 ERI3-IT1 HGNC:HGNC:41431|Ensembl:ENSG00000233602 +100874281 NTM-IT HGNC:HGNC:41437 +100874282 MLIP-IT1 HGNC:HGNC:41461|Ensembl:ENSG00000236996 +100874283 UPP2-IT1 HGNC:HGNC:41467 +100874284 DNM3-IT1 HGNC:HGNC:41494|Ensembl:ENSG00000233540 +100874286 NRG1-IT3 HGNC:HGNC:43635|Ensembl:ENSG00000254049 +100874287 TSPY24P HGNC:HGNC:38725 +100874288 TSPY25P HGNC:HGNC:38726 +100874289 VDAC1P12 HGNC:HGNC:39680 +100874290 RERG-IT1 HGNC:HGNC:39991 +100874291 ALMS1-IT1 HGNC:HGNC:41305|Ensembl:ENSG00000230002 +100874292 CDC42-IT1 HGNC:HGNC:41317 +100874293 GPC5-IT1 HGNC:HGNC:41340 +100874294 HLCS-IT1 HGNC:HGNC:41343 +100874295 KCND3-IT1 HGNC:HGNC:41350|Ensembl:ENSG00000232558 +100874296 KCNH1-IT1 HGNC:HGNC:41351 +100874298 RASA2-IT1 HGNC:HGNC:41376 +100874299 KDM5C-IT1 HGNC:HGNC:41384 +100874300 SYNJ2-IT1 HGNC:HGNC:41387|Ensembl:ENSG00000233496 +100874301 EIPR1-IT1 HGNC:HGNC:41392 +100874302 ITCH-IT1 HGNC:HGNC:41397 +100874303 ALG9-IT1 HGNC:HGNC:41409 +100874305 NAV2-IT1 HGNC:HGNC:41416 +100874306 ACAP2-IT1 HGNC:HGNC:41426 +100874307 RSF1-IT2 HGNC:HGNC:41438 +100874308 RSF1-IT1 HGNC:HGNC:41439 +100874309 EPN2-IT1 HGNC:HGNC:41445 +100874310 MAST4-IT1 HGNC:HGNC:41448 +100874311 ATG10-IT1 HGNC:HGNC:41455 +100874312 FNDC1-IT1 HGNC:HGNC:41460 +100874313 AGBL4-IT1 HGNC:HGNC:41482|Ensembl:ENSG00000225623 +100874314 TTLL7-IT1 HGNC:HGNC:41486 +100874315 SIK3-IT1 HGNC:HGNC:41495 +100874317 FABP7P2 HGNC:HGNC:41952 +100874319 NAP1L4P2 HGNC:HGNC:39739 +100874321 RASA3-IT1 HGNC:HGNC:39938 +100874322 BACH1-IT2 HGNC:HGNC:40007 +100874323 HOXA10-AS HGNC:HGNC:40281|Ensembl:ENSG00000253187 +100874324 ATP2B2-IT1 HGNC:HGNC:41309 +100874325 ATP2B2-IT2 HGNC:HGNC:41310|Ensembl:ENSG00000224771 +100874326 DSCAM-IT1 HGNC:HGNC:41327|Ensembl:ENSG00000233756 +100874327 DSCR4-IT1 HGNC:HGNC:41328 +100874330 LINC01014 HGNC:HGNC:41353|Ensembl:ENSG00000223941 +100874331 LARGE-IT1 HGNC:HGNC:41357 +100874332 OPCML-IT2 HGNC:HGNC:41365 +100874333 OPCML-IT1 HGNC:HGNC:41366 +100874334 TCF7L1-IT1 HGNC:HGNC:41388 +100874337 PLCB1-IT1 HGNC:HGNC:41414 +100874338 TRIM36-IT1 HGNC:HGNC:41422 +100874339 ZNRF3-IT1 HGNC:HGNC:41440 +100874340 CAMTA1-IT1 HGNC:HGNC:41446 +100874342 RNF216-IT1 HGNC:HGNC:41463|Ensembl:ENSG00000237738 +100874343 HS1BP3-IT1 HGNC:HGNC:41474|Ensembl:ENSG00000231948 +100874344 FBXO36-IT1 HGNC:HGNC:41489 +100874345 ZBTB40-IT1 HGNC:HGNC:41493 +100874346 NCKAP5-IT1 HGNC:HGNC:41497 +100874348 ZDHHC20P3 HGNC:HGNC:39775 +100874350 HOXB-AS2 HGNC:HGNC:40284 +100874351 HOXB-AS4 HGNC:HGNC:40285 +100874352 AMMECR1-IT1 HGNC:HGNC:41306 +100874353 RPS6KA2-IT1 HGNC:HGNC:41378|Ensembl:ENSG00000232082 +100874354 ST6GAL2-IT1 HGNC:HGNC:41380 +100874355 ARHGEF9-IT1 HGNC:HGNC:41401|Ensembl:ENSG00000231729 +100874356 TSPAN9-IT1 HGNC:HGNC:41462 +100874358 RNY1P9 HGNC:HGNC:41481 +100874359 TMEM212-IT1 HGNC:HGNC:41505 +100874360 GRPEL2P1 HGNC:HGNC:41969 +100874361 PPP2R2B-IT1 HGNC:HGNC:42984|Ensembl:ENSG00000249553 +100874362 HOXB-AS1 HGNC:HGNC:43744|Ensembl:ENSG00000230148 +100874363 HOXC-AS1 HGNC:HGNC:43749|Ensembl:ENSG00000250451 +100874364 HOXC-AS2 HGNC:HGNC:43750|Ensembl:ENSG00000250133 +100874365 HOXC-AS3 HGNC:HGNC:43751|Ensembl:ENSG00000251151 +100874366 HOXC13-AS HGNC:HGNC:43753|Ensembl:ENSG00000249641 +100874367 ZDHHC20-IT1 HGNC:HGNC:39900 +100874369 CACNA1C-IT2 HGNC:HGNC:41313|Ensembl:ENSG00000256257 +100874370 CACNA1C-IT3 HGNC:HGNC:41314 +100874371 ARHGEF7-IT1 HGNC:HGNC:41408 +100874372 ARHGAP26-IT1 HGNC:HGNC:41429|Ensembl:ENSG00000230789 +100874373 STARD13-IT1 HGNC:HGNC:41453 +100874374 ARHGEF38-IT1 HGNC:HGNC:41483|Ensembl:ENSG00000249885 +100874375 FAM155A-IT1 HGNC:HGNC:41503 +100874377 SMIM2-IT1 HGNC:HGNC:41492|Ensembl:ENSG00000235285 +100874378 PTGER4P3 HGNC:HGNC:38498 +100874379 POM121L13P HGNC:HGNC:42635 +100874380 DPPA5P2 HGNC:HGNC:43754 +100874381 NPIPP1 HGNC:HGNC:35407 +100874382 USP9YP12 HGNC:HGNC:38720 +100874383 USP9YP22 HGNC:HGNC:38758 +100874384 USP9YP30 HGNC:HGNC:38766 +100874385 HNRNPKP5 HGNC:HGNC:42378 +100874386 OSTCP5 HGNC:HGNC:42867 +100874387 OSTCP6 HGNC:HGNC:42868 +100874388 OSTCP8 HGNC:HGNC:42869 +100874389 CNOT4P1 HGNC:HGNC:39272 +100874390 RAC1P7 HGNC:HGNC:42007 +100874391 OSTCP7 HGNC:HGNC:42870 +100874392 ANKRD20A12P HGNC:HGNC:43603 +100874393 EIF2AP1 HGNC:HGNC:39495 +100874394 EIF2AP2 HGNC:HGNC:39496 +100874395 EIF2AP3 HGNC:HGNC:39497 +100874396 HNRNPA1P24 HGNC:HGNC:39542 +100874397 CDKN2AIPNLP3 HGNC:HGNC:39853 +100874398 RAC1P8 HGNC:HGNC:42005 +100874399 IMPDH1P10 HGNC:HGNC:33965 +100874400 HNRNPA1P18 HGNC:HGNC:39445 +100874401 EIF2AP4 HGNC:HGNC:39498 +100874402 HNRNPA1P19 HGNC:HGNC:39537 +100874403 ERHP2 HGNC:HGNC:41917 +100874404 LINC00328-2P HGNC:HGNC:42027 +100874405 PPIAP27 HGNC:HGNC:42646 +100874406 FAM106DP HGNC:HGNC:38397 +100874407 SNRPGP3 HGNC:HGNC:39322 +100874408 SNRPGP7 HGNC:HGNC:39326 +100874409 SNRPGP8 HGNC:HGNC:39327 +100874410 HMGN1P9 HGNC:HGNC:39352 +100874411 SNRPFP2 HGNC:HGNC:39665 +100874412 SNRPFP4 HGNC:HGNC:39667 +100874413 SNRPEP5 HGNC:HGNC:43447 +100874414 SNRPEP6 HGNC:HGNC:43571 +100874415 SNRPEP7 HGNC:HGNC:43572 +100874416 SNRPEP9 HGNC:HGNC:43574 +100874417 TIMM8BP2 HGNC:HGNC:39212 +100874418 SNRPGP5 HGNC:HGNC:39324 +100874419 IPPKP1 HGNC:HGNC:39390 +100874420 ARL2BPP5 HGNC:HGNC:39449 +100874421 ARL2BPP6 HGNC:HGNC:39450 +100874422 SNRPFP3 HGNC:HGNC:39666 +100874423 SNRPEP8 HGNC:HGNC:43573 +100874424 SNRPEP10 HGNC:HGNC:43575 +100874425 TIMM8BP1 HGNC:HGNC:39211 +100874426 SNRPGP11 HGNC:HGNC:39330 +100874427 SNRPGP12 HGNC:HGNC:39331 +100874428 SNRPGP13 HGNC:HGNC:39332 +100874429 HMGN1P5 HGNC:HGNC:39348 +100874430 HMGN1P6 HGNC:HGNC:39349 +100874431 HMGN1P8 HGNC:HGNC:39351 +100874432 TCEAL4P1 HGNC:HGNC:39582 +100874433 IQCJ-SCHIP1-AS1 HGNC:HGNC:41303 +100874434 SNRPGP14 HGNC:HGNC:42039 +100874435 HIGD1AP4 HGNC:HGNC:43000 +100874436 HIGD1AP6 HGNC:HGNC:43001 +100874437 HIGD1AP7 HGNC:HGNC:43002 +100874438 HMGN1P10 HGNC:HGNC:39353 +100874439 HMGN1P13 HGNC:HGNC:39357 +100874440 HMGN1P14 HGNC:HGNC:39358 +100874441 HMGN1P15 HGNC:HGNC:39359 +100874442 HMGN1P16 HGNC:HGNC:39360 +100874443 HMGN1P17 HGNC:HGNC:39361 +100874444 HMGN1P18 HGNC:HGNC:39362 +100874445 HMGN1P19 HGNC:HGNC:39363 +100874446 HMGN1P33 HGNC:HGNC:39377 +100874447 HMGN1P34 HGNC:HGNC:39378 +100874448 HMGN1P35 HGNC:HGNC:39379 +100874449 ARL2BPP10 HGNC:HGNC:39454 +100874450 HIGD1AP2 HGNC:HGNC:42642 +100874451 HIGD1AP8 HGNC:HGNC:43003 +100874452 HIGD1AP9 HGNC:HGNC:43004 +100874453 HIGD1AP11 HGNC:HGNC:43006 +100874454 HIGD1AP13 HGNC:HGNC:43008 +100874455 HIGD1AP14 HGNC:HGNC:43009 +100874456 HIGD1AP18 HGNC:HGNC:43013 +100874457 CASP1P1 HGNC:HGNC:43775 +100874458 HMGN2P14 HGNC:HGNC:23341 +100874459 HMGN1P20 HGNC:HGNC:39364 +100874460 HMGN1P22 HGNC:HGNC:39366 +100874461 HMGN1P23 HGNC:HGNC:39367 +100874462 HMGN1P24 HGNC:HGNC:39368 +100874463 HMGN1P27 HGNC:HGNC:39371 +100874464 HMGN1P28 HGNC:HGNC:39372 +100874465 HMGN1P32 HGNC:HGNC:39376 +100874466 HMGN2P19 HGNC:HGNC:39383 +100874467 HMGN2P21 HGNC:HGNC:39386 +100874468 HMGN2P22 HGNC:HGNC:39387 +100874469 HMGN2P23 HGNC:HGNC:39388 +100874470 HMGN2P26 HGNC:HGNC:39393 +100874471 HMGN2P27 HGNC:HGNC:39394 +100874472 HMGN2P29 HGNC:HGNC:39396 +100874473 HMGN2P32 HGNC:HGNC:39403 +100874474 HMGN2P33 HGNC:HGNC:39404 +100874475 HMGN2P45 HGNC:HGNC:39416 +100874476 HIGD1AP16 HGNC:HGNC:43011 +100874477 HIGD1AP17 HGNC:HGNC:43012 +100874478 HMGN2P34 HGNC:HGNC:39405 +100874479 HMGN2P35 HGNC:HGNC:39406 +100874480 HMGN2P36 HGNC:HGNC:39407 +100874481 HMGN2P37 HGNC:HGNC:39408 +100874482 HMGN2P38 HGNC:HGNC:39409 +100874483 HMGN2P39 HGNC:HGNC:39410 +100874484 HMGN2P40 HGNC:HGNC:39411 +100874485 HMGN2P42 HGNC:HGNC:39413 +100874486 HMGN2P43 HGNC:HGNC:39414 +100874487 HMGN2P44 HGNC:HGNC:39415 +100874488 NIPA2P5 HGNC:HGNC:42045 +100874489 DDX3P2 HGNC:HGNC:42172 +100874490 EEF1A1P40 HGNC:HGNC:37918 +100874491 EEF1A1P41 HGNC:HGNC:38799 +100874492 BRK1P2 HGNC:HGNC:42021 +100874493 PIEZO1P2 HGNC:HGNC:42861 +100874494 CYP46A4P HGNC:HGNC:42349 +100874495 CYP4A43P HGNC:HGNC:42417 +100874497 RBMY1KP HGNC:HGNC:38750 +100874498 SPTLC1P2 HGNC:HGNC:39669 +100874499 SPTLC1P3 HGNC:HGNC:39670 +100874500 SPTLC1P4 HGNC:HGNC:39671 +100874501 NME1P1 HGNC:HGNC:39904 +100874502 ATP6V0E1P1 HGNC:HGNC:41935 +100874503 ATP6V0E1P2 HGNC:HGNC:41936 +100874504 ATP6V0E1P4 HGNC:HGNC:41938 +100874505 CYP2C59P HGNC:HGNC:42406 +100874506 CHCHD2P1 HGNC:HGNC:39585 +100874507 CHCHD2P4 HGNC:HGNC:39588 +100874508 CHCHD2P5 HGNC:HGNC:39589 +100874509 CHCHD2P7 HGNC:HGNC:39591 +100874510 PSMA6P3 HGNC:HGNC:39608 +100874511 SPTLC1P1 HGNC:HGNC:39668 +100874512 SPTLC1P5 HGNC:HGNC:39672 +100874513 CYP2C115P HGNC:HGNC:42405 +100874514 ATP6V1G1P7 HGNC:HGNC:39852 +100874515 POLR2KP1 HGNC:HGNC:42650 +100874516 LAMTOR3P2 HGNC:HGNC:39727 +100874517 TOMM22P4 HGNC:HGNC:38740 +100874518 ATP8A2P3 HGNC:HGNC:42641 +100874519 ELOBP4 HGNC:HGNC:39722 +100874520 PCMTD1P1 HGNC:HGNC:38804 +100874521 ST13P22 HGNC:HGNC:38865 +100874522 SLC25A15P2 HGNC:HGNC:39843 +100874523 HIF1AP1 HGNC:HGNC:43016 +100874524 ST6GALNAC4P1 HGNC:HGNC:39660 +100874527 C16DELQ22 MIM:614541 +100874528 XXYLT1-AS1 HGNC:HGNC:41153|Ensembl:ENSG00000233303 +100874529 MPRIP-AS1 HGNC:HGNC:41263 +100874530 APOBEC3B-AS1 HGNC:HGNC:43836|Ensembl:ENSG00000249310 +100874531 LINC00581 HGNC:HGNC:43840|Ensembl:ENSG00000280989 +100874532 IBGC2 MIM:606656 +100874533 DUPXQ27.3Q28 MIM:300869 +100884129 DUP17Q12 MIM:614526 +100884130 DEL17Q12 MIM:614527 +100884155 MTND2P9 HGNC:HGNC:42110 +100884169 LOC100884169 - +100885773 DYT21 MIM:614588|HGNC:HGNC:39436 +100885774 PDCOS MIM:614590 +100885775 BANCR HGNC:HGNC:43877 +100885776 UGDH-AS1 HGNC:HGNC:40601|Ensembl:ENSG00000249348 +100885777 PCCA-AS1 HGNC:HGNC:39901 +100885778 NALCN-AS1 HGNC:HGNC:42743|Ensembl:ENSG00000233009 +100885779 LINC-ROR MIM:615173|HGNC:HGNC:43773|Ensembl:ENSG00000258609 +100885780 VWC2L-IT1 HGNC:HGNC:41508|Ensembl:ENSG00000224257 +100885781 LINC00348 HGNC:HGNC:42658|Ensembl:ENSG00000226846 +100885782 MYO16-AS1 HGNC:HGNC:39913|Ensembl:ENSG00000236242 +100885786 NMLFS MIM:608156 +100885787 DEL8Q12Q21 MIM:600257 +100885788 OTDD MIM:166750 +100885789 IFNG-AS1 HGNC:HGNC:43910|Ensembl:ENSG00000255733 +100885795 LARS2-AS1 HGNC:HGNC:40796 +100885796 SLC9A9-AS1 HGNC:HGNC:40928|Ensembl:ENSG00000240012 +100885797 BPY2DP HGNC:HGNC:38794 +100885798 LINC00210 HGNC:HGNC:37458|Ensembl:ENSG00000231814 +100885799 ENO1P4 HGNC:HGNC:37945 +100885800 SNAP47-AS1 HGNC:HGNC:41501 +100885801 KTCN5 MIM:614622 +100885802 KTCN6 MIM:614623 +100885803 KTCN8 MIM:614628 +100885848 PTGES3L HGNC:HGNC:43943|Ensembl:ENSG00000267060|Vega:OTTHUMG00000180906 +100885850 PTGES3L-AARSD1 HGNC:HGNC:43946|Ensembl:ENSG00000108825|Vega:OTTHUMG00000180905 +100885864 RNA5SP244 HGNC:HGNC:43144 +100885865 HMGN1P29 HGNC:HGNC:39373 +100885866 MRPS31P4 HGNC:HGNC:42649 +100886964 PTCSC3 MIM:614821|HGNC:HGNC:43959 +100887067 KRT8P48 HGNC:HGNC:48344 +100887068 LOC100887068 - +100887072 LOC100887072 - +100887073 DUX4L31 HGNC:HGNC:51770 +100887074 DUX4L45 HGNC:HGNC:51783 +100887075 ARHGAP42P1 HGNC:HGNC:43940 +100887076 LOC100887076 - +100887077 LOC100887077 - +100887078 LOC100887078 - +100887080 LOC100887080 - +100887740 RNA5SP411 HGNC:HGNC:43311 +100887743 DELXQ21 MIM:303110 +100887744 RNU6-48P HGNC:HGNC:34292 +100887745 MTND1P13 HGNC:HGNC:42096 +100887746 UNC93B7 HGNC:HGNC:44036 +100887747 EEF1A1P18 HGNC:HGNC:37891 +100887748 UNC93B8 HGNC:HGNC:44037 +100887749 MTND1P23 HGNC:HGNC:42092 +100887750 MRPS31P5 HGNC:HGNC:39253|Ensembl:ENSG00000243406 +100887751 MPVQTL6 MIM:614646 +100887752 MPVQTL5 MIM:614645 +100887753 MPVQTL4 MIM:614644 +100887754 LINC00359 HGNC:HGNC:42679 +100887755 TRERNA1 HGNC:HGNC:44307 +100887822 KTCN7 MIM:614629 +100887824 DDX11L11 HGNC:HGNC:37110 +100909384 DUP16P11.2 MIM:614671 +100909385 STUT4 MIM:614668 +100909386 STUT3 MIM:614655 +100909387 CMH21 MIM:614676 +100913082 LOC100913082 - +100913179 LOC100913179 - +100913182 MARCKSL1P2 HGNC:HGNC:45240 +100913183 MARCKSL1P1 HGNC:HGNC:45239 +100913186 BDLN1 MIM:300054 +100913187 APOBEC3A_B HGNC:HGNC:44196 +100967223 LOC100967223 - +100967224 LOC100967224 - +100996246 LINC02361 HGNC:HGNC:53283|Ensembl:ENSG00000256576 +100996247 LOC100996247 - +100996249 LOC100996249 - +100996251 LOC100996251 Ensembl:ENSG00000238198 +100996255 LINC02256 HGNC:HGNC:53157 +100996259 FAM106B HGNC:HGNC:32450 +100996262 LOC100996262 - +100996263 LOC100996263 Ensembl:ENSG00000236866 +100996266 LINC01510 HGNC:HGNC:51196 +100996274 LOC100996274 - +100996279 LINC00269 HGNC:HGNC:26586|Ensembl:ENSG00000215162 +100996280 LINC00911 HGNC:HGNC:48596|Ensembl:ENSG00000259107 +100996284 LOC100996284 - +100996286 LINC02273 HGNC:HGNC:53188|Ensembl:ENSG00000245954 +100996288 LOC100996288 Ensembl:ENSG00000267289 +100996291 LINC01993 HGNC:HGNC:52826|Ensembl:ENSG00000204277 +100996294 LOC100996294 - +100996295 DNAH17-AS1 HGNC:HGNC:48594 +100996301 FOXD3-AS1 HGNC:HGNC:40241|Ensembl:ENSG00000230798 +100996306 TUBB4BP6 HGNC:HGNC:42336 +100996307 LIPE-AS1 HGNC:HGNC:48589|Ensembl:ENSG00000213904 +100996315 CHIAP3 HGNC:HGNC:44464 +100996316 LOC100996316 - +100996318 LOC100996318 - +100996324 LINC01882 HGNC:HGNC:52701|Ensembl:ENSG00000267654 +100996325 LOC100996325 - +100996331 POTEB MIM:608912|HGNC:HGNC:33734|Ensembl:ENSG00000233917|Vega:OTTHUMG00000171734 +100996333 LOC100996333 - +100996335 LOC100996335 Ensembl:ENSG00000206142 +100996337 LOC100996337 - +100996338 LINC02169 HGNC:HGNC:53031 +100996342 LINC01664 HGNC:HGNC:52452|Ensembl:ENSG00000235478 +100996345 LINC02140 HGNC:HGNC:53000|Ensembl:ENSG00000261803 +100996348 CA3-AS1 HGNC:HGNC:51657|Ensembl:ENSG00000253549 +100996349 LOC100996349 - +100996350 DUX4L26 HGNC:HGNC:50807 +100996351 LOC100996351 Ensembl:ENSG00000267551 +100996361 LOC100996361 - +100996362 LOC100996362 - +100996364 LOC100996364 - +100996365 LOC100996365 - +100996375 LOC100996375 - +100996379 LOC100996379 - +100996384 LOC100996384 - +100996385 LOC100996385 Ensembl:ENSG00000248469 +100996387 CICP24 HGNC:HGNC:48831 +100996401 LOC100996401 - +100996404 LOC100996404 - +100996413 LOC100996413 - +100996414 LOC100996414 - +100996415 LOC100996415 - +100996419 LOC100996419 Ensembl:ENSG00000245317 +100996425 LINC02170 HGNC:HGNC:53032|Ensembl:ENSG00000260896 +100996428 LOC100996428 - +100996432 LINC01663 HGNC:HGNC:52451 +100996435 CA15P1 HGNC:HGNC:44364 +100996437 LOC100996437 - +100996438 MED15P6 HGNC:HGNC:48655 +100996442 LOC100996442 - +100996447 LOC100996447 Ensembl:ENSG00000243150 +100996455 LOC100996455 Ensembl:ENSG00000181908 +100996465 LCA10 Ensembl:ENSG00000273769 +100996466 MED15P7 HGNC:HGNC:48656 +100996476 LOC100996476 - +100996478 LINC01964 HGNC:HGNC:52789 +100996481 PRIM2B - +100996483 LOC100996483 - +100996485 C5orf66 HGNC:HGNC:48332 +100996490 LINC01206 HGNC:HGNC:49637|Ensembl:ENSG00000242512 +100996492 CTXND1 HGNC:HGNC:50507|Ensembl:ENSG00000259417|Vega:OTTHUMG00000172080 +100996500 PDSS1P2 HGNC:HGNC:49741 +100996501 HNRNPA1P34 HGNC:HGNC:48763 +100996506 LOC100996506 - +100996511 LINC01355 HGNC:HGNC:50584 +100996517 LOC100996517 - +100996520 RPSAP68 HGNC:HGNC:51920 +100996521 CTXND2 HGNC:HGNC:53440 +100996538 CCDC74BP1 HGNC:HGNC:51917 +100996539 ITPR1-AS1 HGNC:HGNC:44470 +100996541 FAM157C HGNC:HGNC:34081 +100996549 LOC100996549 - +100996556 CA15P3 HGNC:HGNC:44363 +100996564 SSXP1 HGNC:HGNC:30637 +100996567 ANTXRLP1 HGNC:HGNC:45004 +100996569 NAMA HGNC:HGNC:42408|Ensembl:ENSG00000271086 +100996570 NFIA-AS2 HGNC:HGNC:40401|Ensembl:ENSG00000237928 +100996571 CYYR1-AS1 MIM:616021|HGNC:HGNC:39560|Ensembl:ENSG00000197934 +100996573 LOC100996573 - +100996574 LOC100996574 - +100996579 LINC01806 HGNC:HGNC:52599|Ensembl:ENSG00000227403 +100996582 FAM74A7 HGNC:HGNC:34037 +100996583 LOC100996583 Ensembl:ENSG00000228037 +100996585 LOC100996585 - +100996586 LOC100996586 - +100996590 LINC01505 HGNC:HGNC:51186|Ensembl:ENSG00000234323 +100996597 LINC00690 HGNC:HGNC:44503|Ensembl:ENSG00000233570 +100996598 LOC100996598 - +100996600 IGKV2OR2-8 HGNC:HGNC:5811|IMGT/GENE-DB:IGKV2/OR2-8 +100996609 LINC01436 HGNC:HGNC:50754 +100996611 LOC100996611 - +100996624 LINC01981 HGNC:HGNC:52809|Ensembl:ENSG00000229243 +100996630 LINC01760 HGNC:HGNC:52549|Ensembl:ENSG00000228504 +100996631 TCP11X1 HGNC:HGNC:48369 +100996634 C6orf183 HGNC:HGNC:21562 +100996635 LOC100996635 Ensembl:ENSG00000228971 +100996637 LOC100996637 - +100996643 LOC100996643 - +100996645 LINCR-0003 - +100996648 TCP11X2 HGNC:HGNC:48335|Ensembl:ENSG00000215029|Vega:OTTHUMG00000152591 +100996649 ALG1L14P HGNC:HGNC:44383 +100996654 LOC100996654 - +100996660 LOC100996660 - +100996662 LOC100996662 - +100996664 LOC100996664 - +100996665 LINC01533 HGNC:HGNC:51274|Ensembl:ENSG00000267779 +100996669 LINC01544 HGNC:HGNC:51312 +100996670 LOC100996670 - +100996671 LOC100996671 Ensembl:ENSG00000256732 +100996679 LINC02369 HGNC:HGNC:53292|Ensembl:ENSG00000256551 +100996681 LOC100996681 - +100996684 AKR1C5P HGNC:HGNC:44679 +100996686 METTL7AP1 HGNC:HGNC:48874 +100996693 LOC100996693 Ensembl:ENSG00000072195 +100996694 LINC02502 HGNC:HGNC:53491|Ensembl:ENSG00000250392 +100996696 LOC100996696 - +100996699 LOC100996699 - +100996701 LOC100996701 - +100996702 LINC01356 HGNC:HGNC:50587|Ensembl:ENSG00000215866 +100996703 LOC100996703 - +100996709 LOC100996709 - +100996712 SRGAP2D MIM:614705|HGNC:HGNC:43932 +100996713 LOC100996713 - +100996716 LOC100996716 - +100996717 LOC100996717 Ensembl:ENSG00000271383 +100996720 LOC100996720 - +100996721 LOC100996721 - +100996722 LOC100996722 - +100996723 LOC100996723 - +100996724 LOC100996724 - +100996731 LOC100996731 - +100996732 LOC100996732 Ensembl:ENSG00000232527 +100996736 LOC100996736 - +100996737 LOC100996737 - +100996738 HERC2P11 HGNC:HGNC:49882 +100996740 LOC100996740 - +100996741 LOC100996741 - +100996745 LOC100996745 - +100996746 SPDYE11 HGNC:HGNC:51507 +100996747 LOC100996747 - +100996750 LOC100996750 - +100996756 LOC100996756 - +100996758 NPY4R2 HGNC:HGNC:52383|Ensembl:ENSG00000264717|Vega:OTTHUMG00000188323 +100996763 LOC100996763 Ensembl:ENSG00000270629 +100996792 LOC100996792 Vega:OTTHUMG00000191883 +100996842 LOC100996842 Ensembl:ENSG00000233223 +100996851 XIAPP1 HGNC:HGNC:52375 +100996860 LOC100996860 - +100996876 RORA-AS2 HGNC:HGNC:51411 +100996886 LOC100996886 - +100996902 LINC01883 HGNC:HGNC:52702 +100996911 LOC100996911 - +100996928 C7orf55-LUC7L2 HGNC:HGNC:44671|Ensembl:ENSG00000269955|Vega:OTTHUMG00000151717 +100996930 LINC00621 HGNC:HGNC:44227 +100996934 UAQTL5 MIM:614746 +100996935 UAQTL6 MIM:614747 +100996939 PYURF HGNC:HGNC:44317|Ensembl:ENSG00000145337|Vega:OTTHUMG00000130949 +100996941 IL21-AS1 HGNC:HGNC:40299|Ensembl:ENSG00000227145 +100996944 NDUFS5P1 HGNC:HGNC:44039 +100996949 PDA1 MIM:607411 +101027084 LOC101027084 - +101027378 ETM3 MIM:611456 +101054525 PGR-AS1 HGNC:HGNC:52650 +101055624 NYS7 MIM:614826 +101055625 OVCH1-AS1 HGNC:HGNC:44484|Ensembl:ENSG00000257599 +101056699 TRK-CTT7-1 HGNC:HGNC:35098 +101056700 NADK2-AS1 HGNC:HGNC:41143 +101056702 HHV8S MIM:614836 +101059903 HMSN5 MIM:600361 +101059905 ELOCP26 HGNC:HGNC:38731 +101059906 LOC101059906 - +101059907 LOC101059907 - +101059914 FAM218BP HGNC:HGNC:43779 +101059915 LOC101059915 Ensembl:ENSG00000283599|Vega:OTTHUMG00000191693 +101059916 NUP35P2 HGNC:HGNC:52371 +101059918 GOLGA8R HGNC:HGNC:44407|Ensembl:ENSG00000186399|Vega:OTTHUMG00000175646 +101059920 FRG2HP HGNC:HGNC:51794 +101059924 LOC101059924 - +101059926 FRG2JP HGNC:HGNC:51796 +101059935 LOC101059935 - +101059938 NPIPA7 HGNC:HGNC:41982|Ensembl:ENSG00000214967|Vega:OTTHUMG00000166307 +101059945 LOC101059945 - +101059948 LOC101059948 Ensembl:ENSG00000268655 +101059949 LOC101059949 - +101059953 NPIPA8 HGNC:HGNC:41983|Ensembl:ENSG00000214940|Vega:OTTHUMG00000166284 +101059954 LOC101059954 - +101059962 LOC101059962 - +101059972 LOC101059972 - +101059973 NACAP7 HGNC:HGNC:49494 +101059974 LOC101059974 - +101059977 LOC101059977 - +101059982 TCEAL8P1 HGNC:HGNC:45245 +101059986 LOC101059986 - +101059988 BNIP3P41 HGNC:HGNC:49721 +101059990 LOC101059990 - +101059996 LOC101059996 - +101059997 LOC101059997 - +101060000 LOC101060000 - +101060004 LINC01523 HGNC:HGNC:51225 +101060005 SOD1P3 HGNC:HGNC:45136 +101060006 NANOGNBP2 HGNC:HGNC:42159 +101060015 LOC101060015 - +101060016 LOC101060016 - +101060017 LOC101060017 - +101060019 LINC01799 HGNC:HGNC:52589|Ensembl:ENSG00000230525 +101060020 OLA1P3 HGNC:HGNC:45278 +101060021 LOC101060021 - +101060022 LOC101060022 - +101060024 LOC101060024 - +101060032 RHEBP2 HGNC:HGNC:44991 +101060035 LOC101060035 - +101060038 LINC02446 HGNC:HGNC:53378 +101060039 HNRNPA1P57 HGNC:HGNC:48787 +101060040 CHCHD2P11 HGNC:HGNC:49029 +101060042 LOC101060042 - +101060043 LOC101060043 - +101060045 PCBP2P1 HGNC:HGNC:8649 +101060048 LOC101060048 - +101060049 LOC101060049 - +101060051 LOC101060051 - +101060052 LOC101060052 - +101060056 LOC101060056 - +101060058 LOC101060058 - +101060064 LOC101060064 - +101060066 LOC101060066 - +101060067 LOC101060067 - +101060076 LOC101060076 - +101060084 LOC101060084 - +101060086 LOC101060086 - +101060089 LOC101060089 - +101060090 LOC101060090 - +101060091 LOC101060091 - +101060097 LOC101060097 - +101060098 LOC101060098 - +101060099 LOC101060099 - +101060104 LOC101060104 - +101060105 FAM183DP HGNC:HGNC:51331 +101060111 LUZP4P1 HGNC:HGNC:44904 +101060112 LOC101060112 - +101060113 LOC101060113 - +101060118 LOC101060118 - +101060119 LOC101060119 - +101060126 LOC101060126 - +101060128 LOC101060128 - +101060144 MED28P8 HGNC:HGNC:45085 +101060145 LOC101060145 - +101060146 CHMP1B2P HGNC:HGNC:49380|Ensembl:ENSG00000278530 +101060152 LOC101060152 - +101060158 LOC101060158 - +101060159 LOC101060159 - +101060160 DDTP1 HGNC:HGNC:44546 +101060162 LOC101060162 - +101060164 LOC101060164 - +101060170 LOC101060170 - +101060171 ARMC4P1 HGNC:HGNC:44937 +101060173 LOC101060173 - +101060176 TPRKBP1 HGNC:HGNC:44943 +101060179 LOC101060179 - +101060187 LOC101060187 - +101060189 UBE2FP2 HGNC:HGNC:44536 +101060191 LOC101060191 - +101060192 BNIP3P13 HGNC:HGNC:49693 +101060195 FCF1P2 HGNC:HGNC:44614 +101060199 LOC101060199 - +101060200 ZNF891 HGNC:HGNC:38709|Ensembl:ENSG00000214029|Vega:OTTHUMG00000167943 +101060206 LOC101060206 - +101060207 LOC101060207 - +101060211 CT45A7 HGNC:HGNC:51260|Ensembl:ENSG00000273696|Vega:OTTHUMG00000022491 +101060212 LOC101060212 - +101060224 LOC101060224 - +101060226 NBPF19 MIM:614006|HGNC:HGNC:31999 +101060227 LOC101060227 - +101060233 OPN1MW3 HGNC:HGNC:51831|Ensembl:ENSG00000269433|Vega:OTTHUMG00000189499 +101060236 LOC101060236 - +101060254 LOC101060254 - +101060264 FOXP4-AS1 HGNC:HGNC:50332|Ensembl:ENSG00000234753 +101060274 LOC101060274 - +101060275 LOC101060275 - +101060280 SPDYE20P HGNC:HGNC:51516 +101060301 HNRNPCL4 HGNC:HGNC:51333|Ensembl:ENSG00000179412|Vega:OTTHUMG00000189238 +101060304 LOC101060304 - +101060321 TBC1D3G MIM:610810|HGNC:HGNC:29860|Ensembl:ENSG00000260287|Vega:OTTHUMG00000188426 +101060324 LOC101060324 - +101060341 LOC101060341 - +101060351 TBC1D3K HGNC:HGNC:51245|Ensembl:ENSG00000273513|Vega:OTTHUMG00000188481 +101060363 LOC101060363 - +101060376 TBC1D3L HGNC:HGNC:51246|Ensembl:ENSG00000274512|Vega:OTTHUMG00000188482 +101060385 LINC01939 HGNC:HGNC:52762|Ensembl:ENSG00000228799 +101060386 LOC101060386 - +101060389 TBC1D3D MIM:610807|HGNC:HGNC:28944|Ensembl:ENSG00000274419|Vega:OTTHUMG00000188483 +101060390 LOC101060390 - +101060391 LOC101060391 - +101060398 LOC101060398 - +101060399 LOC101060399 - +101060400 LOC101060400 - +101060405 LOC101060405 - +101060424 LOC101060424 - +101060442 LOC101060442 - +101060445 LOC101060445 - +101060458 LOC101060458 - +101060476 LOC101060476 - +101060498 LINC02265 HGNC:HGNC:53179|Ensembl:ENSG00000249241 +101060501 LOC101060501 - +101060521 LOC101060521 - +101060524 LOC101060524 - +101060542 LINC01910 HGNC:HGNC:52729|Ensembl:ENSG00000266278 +101060544 LINC01563 HGNC:HGNC:51343|Ensembl:ENSG00000236819 +101060553 LOC101060553 - +101060569 LOC101060569 - +101060580 LOC101060580 - +101060587 LOC101060587 - +101060588 LOC101060588 - +101060596 LOC101060596 - +101060604 LOC101060604 - +101060632 LOC101060632 - +101060637 LOC101060637 - +101060684 NBPF26 HGNC:HGNC:49571|Ensembl:ENSG00000273136 +101060691 NUTM2B-AS1 HGNC:HGNC:51204|Ensembl:ENSG00000225484 +101060696 LOC101060696 - +101060796 LOC101060796 - +101060825 LOC101060825 - +101060852 LOC101060852 - +101060869 LVSKS MIM:614846 +101101692 HELLPAR MIM:614985|HGNC:HGNC:43984 +101101698 POROK7 MIM:614714 +101101768 ECTD8 MIM:602401 +101101769 ECTD5 MIM:614927 +101101770 ECTD6 MIM:614928 +101101771 ECTD7 MIM:614929 +101101772 LINC00601 HGNC:HGNC:43916|Ensembl:ENSG00000235180 +101101773 LINC00609 HGNC:HGNC:43960|Ensembl:ENSG00000257585 +101101775 TMEM220-AS1 HGNC:HGNC:44357|Ensembl:ENSG00000263400 +101101776 BMS1P17 HGNC:HGNC:49162|Ensembl:ENSG00000228294 +101101841 LOC101101841 - +101154642 CHDT3 MIM:614954 +101154643 LOC101154643 - +101154644 LINCMD1 MIM:614933|HGNC:HGNC:49089 +101154649 MBNP MIM:614692 +101154686 MROH4P HGNC:HGNC:44902 +101154687 LINC01081 MIM:614977|HGNC:HGNC:49124 +101154752 PPKP1B MIM:614936 +101154753 PANDAR MIM:617179|HGNC:HGNC:44048|Ensembl:ENSG00000281450 +101180897 LOC101180897 - +101180899 UCH1LAS MIM:614991 +101180900 MSE MIM:614996 +101180901 IPO11-LRRC70 Ensembl:ENSG00000086200|Vega:OTTHUMG00000154400 +101180907 USH1K MIM:614990|HGNC:HGNC:43724 +101180976 IFNL4 MIM:615090|HGNC:HGNC:44480|Ensembl:ENSG00000272395|Vega:OTTHUMG00000185299 +101202686 ARCI7 MIM:615022 +101202687 ARCI9 MIM:615023 +101232810 LOC101232810 - +101234261 LSINCT5 MIM:615764|HGNC:HGNC:37824 +101234262 COX5BP6 HGNC:HGNC:2275 +101241875 RPS3AP1 HGNC:HGNC:10422 +101241877 ATP5J2LP HGNC:HGNC:849 +101241878 USP17L23 HGNC:HGNC:44451 +101241891 LINC00850 MIM:300892|HGNC:HGNC:45092|Ensembl:ENSG00000280752 +101241892 NPTN-IT1 MIM:615176|HGNC:HGNC:45091|Ensembl:ENSG00000281183 +101241897 PAPA5 MIM:263450 +101241898 KAZA2 MIM:611381 +101241899 KAZA3 MIM:611382 +101241900 SMAJ MIM:615048 +101241901 LOC101241901 - +101241902 LOC101241902 - +101243545 LINC02067 HGNC:HGNC:52913|Ensembl:ENSG00000240567 +101243555 PTENP1-AS HGNC:HGNC:48773|Ensembl:ENSG00000281128 +101269108 LOC101269108 - +101290498 AD17 MIM:615080 +101290499 OPHLC MIM:164750 +101290500 SNAP23P1 HGNC:HGNC:16561 +101290501 TBCAP3 HGNC:HGNC:42632 +101290502 SUMO1P4 HGNC:HGNC:33151 +101290503 BANF1P5 HGNC:HGNC:43885 +101290504 YWHAQP6 HGNC:HGNC:37685 +101290506 LRRFIP1P1 HGNC:HGNC:32937 +101290508 YWHAQP9 HGNC:HGNC:37688 +101340250 SNORA11E HGNC:HGNC:33623|Ensembl:ENSG00000221705 +101340251 SNORD124 HGNC:HGNC:33563|Ensembl:ENSG00000238793 +101340252 SNORD121B HGNC:HGNC:33569|Ensembl:ENSG00000238300 +101362076 GVQW1 HGNC:HGNC:31424 +101409188 FAME4 MIM:615127 +101409253 LINC00676 HGNC:HGNC:44394|Ensembl:ENSG00000234854 +101409254 LINC00681 HGNC:HGNC:44423|Ensembl:ENSG00000255494 +101409255 LOC101409255 - +101409256 LOC101409256 - +101409257 EZR-AS1 HGNC:HGNC:40609 +101409258 OSGEPL1-AS1 HGNC:HGNC:41009 +101409261 OGFR-AS1 HGNC:HGNC:40724|Ensembl:ENSG00000229873 +101409262 LOC101409262 - +101409265 GLM7 MIM:613032 +101409266 MRT35 MIM:615162 +101409267 CORD17 MIM:615163|HGNC:HGNC:48676 +101410533 YTHDF3-AS1 HGNC:HGNC:48728|Ensembl:ENSG00000270673 +101410534 DLGAP1-AS4 HGNC:HGNC:44333|Ensembl:ENSG00000263878 +101410535 LAMTOR5-AS1 HGNC:HGNC:40823 +101410536 EVX1-AS HGNC:HGNC:40223|Ensembl:ENSG00000253405 +101410537 MAGEA8-AS1 HGNC:HGNC:45093 +101410538 MMP24-AS1 HGNC:HGNC:44421 +101410540 FANK1-AS1 HGNC:HGNC:43915|Ensembl:ENSG00000233409 +101410541 LINC00678 HGNC:HGNC:44413|Ensembl:ENSG00000254934 +101410542 UCHL1-AS1 HGNC:HGNC:40600|Ensembl:ENSG00000251173 +101410543 XXYLT1-AS2 HGNC:HGNC:41154|Ensembl:ENSG00000230266 +101410544 RMDN2-AS1 HGNC:HGNC:41150 +101410545 STPG2-AS1 HGNC:HGNC:41209|Ensembl:ENSG00000251620 +101410546 CST2P1 HGNC:HGNC:45042 +101447996 RNVU1-8 HGNC:HGNC:48315 +101448070 GLC1P MIM:615141|HGNC:HGNC:41965 +101448071 BWQTL4 MIM:615192 +101448072 RLS8 MIM:615197 +101448202 LOC101448202 - +101515984 LINC01080 MIM:615230|HGNC:HGNC:49123 +101559451 LOC101559451 Ensembl:ENSG00000244184 +101593348 LOC101593348 - +101618237 LOC101618237 - +101669760 PAURT1 MIM:610420 +101669762 BLACAT1 MIM:615480|HGNC:HGNC:48597 +101669763 JADRR HGNC:HGNC:48601 +101669764 GPR1-AS HGNC:HGNC:48602|Ensembl:ENSG00000279220 +101669766 ZNF350-AS1 HGNC:HGNC:48598|Ensembl:ENSG00000269235 +101669767 SCHLAP1 MIM:615568|HGNC:HGNC:48603|Ensembl:ENSG00000281131 +101730217 SPECC1L-ADORA2A HGNC:HGNC:49185|Ensembl:ENSG00000258555|Vega:OTTHUMG00000150762 +101735302 STAG3L5P HGNC:HGNC:48896|Ensembl:ENSG00000242294 +101752334 PVRIG2P HGNC:HGNC:48897 +101752399 STAG3L5P-PVRIG2P-PILRB HGNC:HGNC:48898|Ensembl:ENSG00000272752 +101752400 CAPN10-AS1 HGNC:HGNC:48839|Ensembl:ENSG00000260942 +101805488 CCAT2 HGNC:HGNC:47044|Ensembl:ENSG00000280997 +101805491 LOC101805491 Ensembl:ENSG00000187600 +101805492 CASC9 HGNC:HGNC:48906 +101822346 TRN-GTT5-1 HGNC:HGNC:38582 +101867536 PRNCR1 MIM:615452|HGNC:HGNC:48942|Ensembl:ENSG00000282961 +101867602 CTRCT29 MIM:115800 +101901828 LOC101901828 - +101901829 LOC101901829 - +101910199 PFFE1 MIM:611384 +101926885 OCA5 MIM:615312|HGNC:HGNC:44139 +101926886 LOC101926886 - +101926887 LOC101926887 - +101926888 RALY-AS1 HGNC:HGNC:50743|Ensembl:ENSG00000228265 +101926889 LOC101926889 - +101926890 DAB1-AS1 HGNC:HGNC:49443|Ensembl:ENSG00000226759 +101926892 LOC101926892 Ensembl:ENSG00000253967 +101926893 LIX1-AS1 HGNC:HGNC:52976 +101926895 CRTC3-AS1 HGNC:HGNC:51433|Ensembl:ENSG00000259736 +101926896 GLIS2-AS1 HGNC:HGNC:51381|Ensembl:ENSG00000262686 +101926897 LINC02338 HGNC:HGNC:53258|Ensembl:ENSG00000277448 +101926898 LOC101926898 - +101926900 DNAJB5-AS1 HGNC:HGNC:49846|Ensembl:ENSG00000281491 +101926903 LSAMP-AS1 HGNC:HGNC:40350|Ensembl:ENSG00000240922 +101926904 LINC01265 HGNC:HGNC:50297|Ensembl:ENSG00000249740 +101926905 LOC101926905 - +101926906 SLC16A12-AS1 HGNC:HGNC:51205|Ensembl:ENSG00000234452 +101926907 LOC101926907 - +101926908 LOC101926908 Ensembl:ENSG00000253726 +101926911 LOC101926911 Ensembl:ENSG00000214432 +101926913 LOC101926913 - +101926915 LOC101926915 - +101926917 ANKRD18CP HGNC:HGNC:43601 +101926918 GTF2IP12 HGNC:HGNC:51723|Ensembl:ENSG00000283050 +101926923 LOC101926923 - +101926924 LINC01375 HGNC:HGNC:50632|Ensembl:ENSG00000226159 +101926925 LINC01358 HGNC:HGNC:50589 +101926926 RDH10-AS1 HGNC:HGNC:51658|Ensembl:ENSG00000250295 +101926928 CRAT37 Ensembl:ENSG00000258551 +101926930 LINC00378 HGNC:HGNC:42704 +101926933 LOC101926933 Ensembl:ENSG00000257285 +101926934 LOC101926934 Ensembl:ENSG00000242973 +101926935 LOC101926935 - +101926938 RPL12P48 HGNC:HGNC:51940 +101926940 LINC02104 HGNC:HGNC:52959|Ensembl:ENSG00000271334 +101926941 SPRY4-AS1 HGNC:HGNC:53465|Ensembl:ENSG00000231185 +101926942 LOC101926942 Ensembl:ENSG00000236373 +101926943 LOC101926943 Ensembl:ENSG00000232729 +101926944 LOC101926944 - +101926945 NXPE2P1 HGNC:HGNC:44082 +101926946 LOC101926946 - +101926947 LINC01617 HGNC:HGNC:30442 +101926948 LOC101926948 - +101926949 LOC101926949 - +101926950 LINC01570 HGNC:HGNC:51382|Ensembl:ENSG00000260338 +101926951 LINC02339 HGNC:HGNC:53259|Ensembl:ENSG00000279797 +101926953 LOC101926953 - +101926955 LINC01733 HGNC:HGNC:52521|Ensembl:ENSG00000226203 +101926956 LOC101926956 - +101926957 ISX-AS1 HGNC:HGNC:41188 +101926958 LOC101926958 - +101926959 LOC101926959 - +101926960 LOC101926960 - +101926962 LOC101926962 - +101926963 LOC101926963 - +101926964 LOC101926964 Ensembl:ENSG00000231252 +101926966 LINC01804 HGNC:HGNC:52596|Ensembl:ENSG00000231031 +101926967 LOC101926967 - +101926968 LOC101926968 - +101926969 LOC101926969 - +101926971 LINC01284 HGNC:HGNC:50342|Ensembl:ENSG00000230317 +101926973 LOC101926973 - +101926974 LOC101926974 - +101926975 LINC01844 HGNC:HGNC:52660|Ensembl:ENSG00000236714 +101926977 LOC101926977 - +101926978 LINC01111 HGNC:HGNC:49237|Ensembl:ENSG00000254300 +101926982 LOC101926982 - +101926983 LINC02049 HGNC:HGNC:52889|Ensembl:ENSG00000243593 +101926984 LOC101926984 - +101926986 LOC101926986 - +101926987 DLGAP4-AS1 HGNC:HGNC:51223|Ensembl:ENSG00000232907 +101926993 LOC101926993 - +101926994 LOC101926994 - +101926996 RUNDC3A-AS1 HGNC:HGNC:51344 +101927000 LOC101927000 Ensembl:ENSG00000229380 +101927003 PKIA-AS1 HGNC:HGNC:51659|Ensembl:ENSG00000254266 +101927006 RPSAP76 HGNC:HGNC:51930 +101927007 LINC01365 HGNC:HGNC:50603|Ensembl:ENSG00000250772 +101927009 LINC02177 HGNC:HGNC:53039|Ensembl:ENSG00000261617 +101927010 LOC101927010 - +101927012 LOC101927012 - +101927013 LOC101927013 - +101927015 LINC01506 HGNC:HGNC:51187|Ensembl:ENSG00000234506 +101927016 LOC101927016 - +101927017 LINC01180 HGNC:HGNC:49558|Ensembl:ENSG00000266979 +101927018 LOC101927018 Ensembl:ENSG00000265845 +101927019 LOC101927019 - +101927020 LOC101927020 - +101927021 LOC101927021 - +101927023 LOC101927023 Ensembl:ENSG00000251076 +101927025 LOC101927025 - +101927026 LOC101927026 - +101927027 LOC101927027 Ensembl:ENSG00000223960 +101927034 ROR1-AS1 HGNC:HGNC:40508|Ensembl:ENSG00000223949 +101927038 LINC02400 HGNC:HGNC:53327|Ensembl:ENSG00000257784 +101927039 LOC101927039 - +101927040 LOC101927040 Ensembl:ENSG00000249328 +101927042 LOC101927042 - +101927043 LOC101927043 Ensembl:ENSG00000234690 +101927044 LOC101927044 - +101927045 LOC101927045 - +101927046 LOC101927046 - +101927048 LOC101927048 - +101927049 PLCE1-AS2 HGNC:HGNC:51206|Ensembl:ENSG00000232913 +101927050 LOC101927050 - +101927051 LOC101927051 Ensembl:ENSG00000233360 +101927053 LOC101927053 - +101927055 LOC101927055 Ensembl:ENSG00000237298 +101927056 LOC101927056 Ensembl:ENSG00000241288 +101927057 LOC101927057 Ensembl:ENSG00000126861 +101927058 LINC02402 HGNC:HGNC:53329|Ensembl:ENSG00000257510 +101927059 LINC01957 HGNC:HGNC:52783|Ensembl:ENSG00000251542 +101927060 LOC101927060 - +101927062 LINC02294 HGNC:HGNC:53210|Ensembl:ENSG00000257845 +101927066 LOC101927066 - +101927067 LINC01607 HGNC:HGNC:51660|Ensembl:ENSG00000272138 +101927069 LOC101927069 - +101927070 LOC101927070 - +101927072 LOC101927072 - +101927073 LOC101927073 - +101927074 LINC00682 HGNC:HGNC:44466|Ensembl:ENSG00000245870 +101927075 FGF10-AS1 HGNC:HGNC:49382|Ensembl:ENSG00000248464 +101927078 LOC101927078 - +101927079 LOC101927079 Ensembl:ENSG00000284500 +101927080 LOC101927080 - +101927081 MIR4307HG HGNC:HGNC:52004|Ensembl:ENSG00000257612 +101927082 LOC101927082 - +101927084 LINC01359 HGNC:HGNC:50591|Ensembl:ENSG00000226891 +101927086 LOC101927086 - +101927087 LINC02516 HGNC:HGNC:53505|Ensembl:ENSG00000261083 +101927088 LOC101927088 - +101927089 LOC101927089 - +101927093 LOC101927093 - +101927094 LOC101927094 - +101927096 CLMAT3 HGNC:HGNC:52287|Ensembl:ENSG00000249035 +101927098 LOC101927098 - +101927100 LOC101927100 - +101927101 RPS3AP54 HGNC:HGNC:49750 +101927102 ITFG1-AS1 HGNC:HGNC:51383 +101927108 LOC101927108 - +101927109 LINC02379 HGNC:HGNC:53302 +101927111 SUCLG2-AS1 HGNC:HGNC:49643|Ensembl:ENSG00000241316 +101927112 LINC01581 HGNC:HGNC:51415|Ensembl:ENSG00000259724 +101927115 LINC01933 HGNC:HGNC:52756|Ensembl:ENSG00000254226 +101927117 PLCG1-AS1 HGNC:HGNC:40450|Ensembl:ENSG00000226648 +101927118 LOC101927118 - +101927120 LOC101927120 Ensembl:ENSG00000255433 +101927123 LINC02016 HGNC:HGNC:52851|Ensembl:ENSG00000244215 +101927124 LOC101927124 Ensembl:ENSG00000250365 +101927125 ELFN1-AS1 HGNC:HGNC:39071|Ensembl:ENSG00000236081 +101927126 GTF2IP7 HGNC:HGNC:51720 +101927129 LINC01580 HGNC:HGNC:51414|Ensembl:ENSG00000258785 +101927131 LOC101927131 Ensembl:ENSG00000262999 +101927132 LINC02133 HGNC:HGNC:52993|Ensembl:ENSG00000261231 +101927134 LINC01470 HGNC:HGNC:51105|Ensembl:ENSG00000249484 +101927136 LOC101927136 Ensembl:ENSG00000231683 +101927138 LOC101927138 - +101927139 LOC101927139 Ensembl:ENSG00000227466 +101927141 LOC101927141 Ensembl:ENSG00000254394 +101927142 LOC101927142 - +101927143 LOC101927143 Ensembl:ENSG00000232628 +101927145 LOC101927145 - +101927149 LINC01471 HGNC:HGNC:51106|Ensembl:ENSG00000239921 +101927150 L3MBTL4-AS1 HGNC:HGNC:51320 +101927151 LOC101927151 Ensembl:ENSG00000267575 +101927152 SAMMSON MIM:616895|HGNC:HGNC:49644|Ensembl:ENSG00000240405 +101927153 LINC02207 HGNC:HGNC:53073 +101927155 LMO7-AS1 HGNC:HGNC:50277|Ensembl:ENSG00000261105 +101927156 LINC01934 HGNC:HGNC:52757|Ensembl:ENSG00000234663 +101927157 LOC101927157 - +101927158 RPSAP69 HGNC:HGNC:51922 +101927159 LOC101927159 Ensembl:ENSG00000229042 +101927164 LOC101927164 Ensembl:ENSG00000237101 +101927165 LINC01813 HGNC:HGNC:52617 +101927166 LOC101927166 - +101927167 GATA2-AS1 HGNC:HGNC:51108 +101927168 LOC101927168 - +101927171 LINC01564 HGNC:HGNC:51361|Ensembl:ENSG00000235899 +101927172 LOC101927172 - +101927174 CHL1-AS2 HGNC:HGNC:40147 +101927176 LINC01069 HGNC:HGNC:49109 +101927178 LOC101927178 Ensembl:ENSG00000151327|Vega:OTTHUMG00000140217 +101927179 LOC101927179 - +101927180 LOC101927180 - +101927182 LOC101927182 - +101927183 LOC101927183 - +101927186 ADGRL3-AS1 HGNC:HGNC:50604 +101927188 LOC101927188 Ensembl:ENSG00000265069 +101927189 LOC101927189 Ensembl:ENSG00000236740 +101927190 LOC101927190 - +101927191 LOC101927191 - +101927193 CHL1-AS1 HGNC:HGNC:40148|Ensembl:ENSG00000234661 +101927195 LINC00382 HGNC:HGNC:42709|Ensembl:ENSG00000229175 +101927196 LOC101927196 Ensembl:ENSG00000226747 +101927198 LOC101927198 - +101927200 LOC101927200 - +101927202 LOC101927202 - +101927204 LOC101927204 Ensembl:ENSG00000245571 +101927207 LINC02075 HGNC:HGNC:52921|Ensembl:ENSG00000249497 +101927209 LOC101927209 - +101927211 LOC101927211 - +101927213 LOC101927213 - +101927215 LINC01266 HGNC:HGNC:50309|Ensembl:ENSG00000224957 +101927216 LOC101927216 Ensembl:ENSG00000284196 +101927217 LINC01473 HGNC:HGNC:51109|Ensembl:ENSG00000237877 +101927219 HNF4A-AS1 HGNC:HGNC:49505|Ensembl:ENSG00000229005 +101927220 DEPDC1-AS1 HGNC:HGNC:50592|Ensembl:ENSG00000234264 +101927221 UBR5-AS1 HGNC:HGNC:51661|Ensembl:ENSG00000246263 +101927222 GAS2L1P1 HGNC:HGNC:50293 +101927224 LINC01049 HGNC:HGNC:49043 +101927226 LOC101927226 - +101927227 LOC101927227 - +101927228 LINC02179 HGNC:HGNC:53041|Ensembl:ENSG00000261623 +101927229 LINC01929 HGNC:HGNC:52751|Ensembl:ENSG00000267013 +101927230 LINC01969 HGNC:HGNC:52795|Ensembl:ENSG00000251085 +101927233 SEMA6A-AS1 HGNC:HGNC:51110|Ensembl:ENSG00000248445 +101927234 LOC101927234 - +101927235 LOC101927235 - +101927237 LOC101927237 Ensembl:ENSG00000250075 +101927238 LOC101927238 - +101927239 LINC01989 HGNC:HGNC:52821|Ensembl:ENSG00000261156 +101927241 LOC101927241 - +101927242 LINC01430 HGNC:HGNC:50742|Ensembl:ENSG00000168746 +101927243 LOC101927243 - +101927244 LINC01788 HGNC:HGNC:52577|Ensembl:ENSG00000229051 +101927245 LOC101927245 - +101927247 LOC101927247 - +101927248 LOC101927248 - +101927249 PDZRN3-AS1 HGNC:HGNC:40814 +101927250 LOC101927250 - +101927252 LOC101927252 - +101927253 LOC101927253 Ensembl:ENSG00000251239 +101927254 LOC101927254 - +101927256 LOC101927256 - +101927257 LOC101927257 Ensembl:ENSG00000232564 +101927258 LINC01474 HGNC:HGNC:51111|Ensembl:ENSG00000236849 +101927259 LOC101927259 - +101927262 LOC101927262 - +101927263 LOC101927263 - +101927264 LOC101927264 - +101927265 BNIP3P7 HGNC:HGNC:49101 +101927267 LOC101927267 Ensembl:ENSG00000258334 +101927268 LOC101927268 - +101927269 LOC101927269 - +101927272 LOC101927272 Ensembl:ENSG00000260249 +101927273 LINC01416 HGNC:HGNC:51645|Ensembl:ENSG00000260930 +101927274 LINC02071 HGNC:HGNC:52917|Ensembl:ENSG00000249383 +101927275 NDUFV2-AS1 HGNC:HGNC:50826|Ensembl:ENSG00000266053 +101927278 LOC101927278 - +101927279 EP300-AS1 HGNC:HGNC:50504 +101927280 LINC02208 HGNC:HGNC:52978 +101927281 LOC101927281 - +101927282 LINC02466 HGNC:HGNC:53405|Ensembl:ENSG00000246876 +101927283 LOC101927283 - +101927284 LOC101927284 - +101927285 LINC01793 HGNC:HGNC:52583|Ensembl:ENSG00000222030 +101927286 LINC02254 HGNC:HGNC:53152|Ensembl:ENSG00000259664 +101927288 MANEA-AS1 HGNC:HGNC:43732|Ensembl:ENSG00000261366 +101927289 LINC01237 HGNC:HGNC:49793|Ensembl:ENSG00000233806 +101927292 LINC02395 HGNC:HGNC:53322|Ensembl:ENSG00000257771 +101927293 LOC101927293 - +101927295 LINC01360 HGNC:HGNC:50593|Ensembl:ENSG00000233973 +101927296 LOC101927296 - +101927297 LOC101927297 - +101927300 LOC101927300 - +101927305 SNHG27 HGNC:HGNC:53481 +101927310 LOC101927310 Ensembl:ENSG00000259582 +101927311 LINC02185 HGNC:HGNC:53047|Ensembl:ENSG00000262097 +101927314 LOC101927314 Ensembl:ENSG00000271860 +101927318 LOC101927318 Ensembl:ENSG00000257588 +101927320 ERICH3-AS1 HGNC:HGNC:41093|Ensembl:ENSG00000234497 +101927322 LOC101927322 - +101927323 PPP4R1-AS1 HGNC:HGNC:51112|Ensembl:ENSG00000263627 +101927324 LINC01475 HGNC:HGNC:51113|Ensembl:ENSG00000257582 +101927325 LOC101927325 - +101927327 SUMO2P20 HGNC:HGNC:49355 +101927329 LOC101927329 - +101927330 LOC101927330 - +101927331 LINC01831 HGNC:HGNC:52637|Ensembl:ENSG00000225765 +101927332 LINC01582 HGNC:HGNC:51416 +101927333 CH17-125A10.2 - +101927334 LINC02127 HGNC:HGNC:52985|Ensembl:ENSG00000261637 +101927342 LOC101927342 - +101927344 LOC101927344 - +101927345 LOC101927345 - +101927346 LINC02047 HGNC:HGNC:52887|Ensembl:ENSG00000239454 +101927347 GRM7-AS3 HGNC:HGNC:42444|Ensembl:ENSG00000226258 +101927348 LINC02186 HGNC:HGNC:53048|Ensembl:ENSG00000261856 +101927350 LINC01254 HGNC:HGNC:49870|Ensembl:ENSG00000260913 +101927351 LINC02302 HGNC:HGNC:53221 +101927352 PLS3-AS1 HGNC:HGNC:50343|Ensembl:ENSG00000271826 +101927353 LOC101927353 - +101927354 LOC101927354 - +101927355 LOC101927355 - +101927356 LOC101927356 Ensembl:ENSG00000223770 +101927357 LOC101927357 - +101927358 LOC101927358 Ensembl:ENSG00000227809 +101927359 LOC101927359 Ensembl:ENSG00000250241 +101927360 LINC01103 HGNC:HGNC:49225|Ensembl:ENSG00000234781 +101927362 LINC01875 HGNC:HGNC:52694|Ensembl:ENSG00000225942 +101927363 LINC02353 HGNC:HGNC:53275|Ensembl:ENSG00000251329 +101927364 LINC01571 HGNC:HGNC:51384|Ensembl:ENSG00000260057 +101927365 LOC101927365 - +101927366 LOC101927366 - +101927367 LOC101927367 - +101927369 LOC101927369 - +101927372 LOC101927372 - +101927374 LOC101927374 - +101927375 LOC101927375 - +101927376 LOC101927376 - +101927377 LOC101927377 Ensembl:ENSG00000231119 +101927378 LOC101927378 Ensembl:ENSG00000235139 +101927379 LINC02201 HGNC:HGNC:53067|Ensembl:ENSG00000251538 +101927380 C9orf41-AS1 HGNC:HGNC:51188 +101927381 LINC01163 HGNC:HGNC:49530|Ensembl:ENSG00000280953 +101927383 LOC101927383 - +101927385 LOC101927385 - +101927388 LOC101927388 - +101927389 LOC101927389 - +101927390 GTF2IP6 HGNC:HGNC:51718 +101927391 LOC101927391 - +101927392 LOC101927392 Ensembl:ENSG00000254041 +101927393 LOC101927393 - +101927394 LOC101927394 Ensembl:ENSG00000227110 +101927396 LINC01514 HGNC:HGNC:51207|Ensembl:ENSG00000237579 +101927397 LOC101927397 - +101927399 PPIAP32 HGNC:HGNC:49531 +101927400 LOC101927400 - +101927401 LOC101927401 - +101927402 LOC101927402 Ensembl:ENSG00000260101 +101927404 LOC101927404 - +101927405 LOC101927405 - +101927406 LINC01821 HGNC:HGNC:52626|Ensembl:ENSG00000225539 +101927410 LOC101927410 Ensembl:ENSG00000260779 +101927411 LINC01782 HGNC:HGNC:52572|Ensembl:ENSG00000267204 +101927412 LINC01781 HGNC:HGNC:52571|Ensembl:ENSG00000234184 +101927413 LOC101927413 - +101927414 LOC101927414 - +101927415 LOC101927415 - +101927416 SRGAP3-AS2 HGNC:HGNC:40899|Ensembl:ENSG00000228723 +101927417 LOC101927417 - +101927418 LOC101927418 Ensembl:ENSG00000258949 +101927419 LOC101927419 Ensembl:ENSG00000229649 +101927420 LOC101927420 Ensembl:ENSG00000224046 +101927421 LOC101927421 - +101927422 GNA14-AS1 HGNC:HGNC:50451|Ensembl:ENSG00000231373 +101927423 PANO1 HGNC:HGNC:51237|Ensembl:ENSG00000274897|Vega:OTTHUMG00000189301 +101927424 LINC01961 HGNC:HGNC:52786|Ensembl:ENSG00000234148 +101927429 LOC101927429 - +101927430 LINC01903 HGNC:HGNC:52722|Ensembl:ENSG00000265555 +101927431 LINC01790 HGNC:HGNC:52579|Ensembl:ENSG00000230173 +101927432 LOC101927432 - +101927433 LINC01255 HGNC:HGNC:49871|Ensembl:ENSG00000267252 +101927434 LOC101927434 Ensembl:ENSG00000234953 +101927436 LOC101927436 - +101927437 LOC101927437 - +101927438 LINC01800 HGNC:HGNC:52590|Ensembl:ENSG00000234572 +101927439 LOC101927439 - +101927440 SRGAP3-AS4 HGNC:HGNC:42434 +101927441 LOC101927441 - +101927445 LOC101927445 - +101927446 LOC101927446 Ensembl:ENSG00000105793 +101927447 LOC101927447 Ensembl:ENSG00000203527 +101927449 LINC01282 HGNC:HGNC:50338|Ensembl:ENSG00000236747 +101927450 LOC101927450 Ensembl:ENSG00000260995 +101927451 LOC101927451 - +101927452 LOC101927452 - +101927454 LOC101927454 - +101927455 TMEM108-AS1 HGNC:HGNC:50307|Ensembl:ENSG00000251011 +101927457 LINC01522 HGNC:HGNC:51224 +101927459 LINC01608 HGNC:HGNC:51662|Ensembl:ENSG00000253877 +101927460 LINC02240 HGNC:HGNC:53118|Ensembl:ENSG00000260192 +101927461 LOC101927461 - +101927464 LINC02359 HGNC:HGNC:53280|Ensembl:ENSG00000256342 +101927465 CLYBL-AS1 HGNC:HGNC:39893 +101927467 LOC101927467 - +101927468 LOC101927468 - +101927469 LOC101927469 - +101927472 LOC101927472 - +101927473 LOC101927473 - +101927474 LOC101927474 - +101927476 LOC101927476 Ensembl:ENSG00000236393 +101927477 LINC01507 HGNC:HGNC:51189 +101927478 LOC101927478 - +101927479 LOC101927479 - +101927480 LOC101927480 Ensembl:ENSG00000245694 +101927481 LINC01909 HGNC:HGNC:52728|Ensembl:ENSG00000266258 +101927482 LOC101927482 - +101927483 LOC101927483 - +101927484 LOC101927484 - +101927486 LOC101927486 - +101927487 LINC01609 HGNC:HGNC:51663|Ensembl:ENSG00000253103 +101927488 LOC101927488 - +101927489 TCERG1L-AS1 HGNC:HGNC:49532|Ensembl:ENSG00000230098 +101927490 LOC101927490 - +101927492 UTAT33 Ensembl:ENSG00000231851 +101927494 LINC02070 HGNC:HGNC:52916|Ensembl:ENSG00000241328 +101927495 LOC101927495 Ensembl:ENSG00000250230 +101927496 LOC101927496 - +101927497 LOC101927497 Ensembl:ENSG00000237819 +101927498 LINC01361 HGNC:HGNC:50595|Ensembl:ENSG00000236268 +101927499 LOC101927499 - +101927501 PINCR HGNC:HGNC:53590|Ensembl:ENSG00000224294 +101927502 LOC101927502 Ensembl:ENSG00000233926 +101927503 LOC101927503 - +101927504 LINC01682 HGNC:HGNC:52470 +101927505 LINC02348 HGNC:HGNC:53270 +101927506 LOC101927506 - +101927509 LOC101927509 - +101927510 LOC101927510 - +101927511 LOC101927511 - +101927512 LOC101927512 - +101927513 LOC101927513 Ensembl:ENSG00000254278 +101927514 LOC101927514 - +101927516 LOC101927516 - +101927518 LOC101927518 - +101927519 TUBBP8 HGNC:HGNC:42179 +101927521 LOC101927521 - +101927522 LOC101927522 - +101927523 LOC101927523 Ensembl:ENSG00000225768 +101927524 MEOX2-AS1 HGNC:HGNC:50672 +101927525 COL1A2-AS1 HGNC:HGNC:53133 +101927526 LINC01656 HGNC:HGNC:52444|Ensembl:ENSG00000232655 +101927528 LINC01204 HGNC:HGNC:49635|Ensembl:ENSG00000229563 +101927531 LOC101927531 Ensembl:ENSG00000255595 +101927532 LINC01736 HGNC:HGNC:52524|Ensembl:ENSG00000228058 +101927533 LOC101927533 Ensembl:ENSG00000204929 +101927534 LOC101927534 - +101927536 LOC101927536 - +101927538 LOC101927538 - +101927539 LOC101927539 Ensembl:ENSG00000263499 +101927540 TOMM20P2 HGNC:HGNC:50519 +101927541 LINC01273 HGNC:HGNC:50329|Ensembl:ENSG00000231742 +101927542 LINC01712 HGNC:HGNC:52499 +101927543 LOC101927543 Ensembl:ENSG00000248318 +101927546 ANO7L1 HGNC:HGNC:32248 +101927547 ANKRD44-IT1 HGNC:HGNC:41477|Ensembl:ENSG00000236977 +101927548 LOC101927548 - +101927549 LOC101927549 - +101927550 LOC101927550 Ensembl:ENSG00000242687 +101927551 LOC101927551 - +101927552 LOC101927552 - +101927553 LINC01737 HGNC:HGNC:52525|Ensembl:ENSG00000232964 +101927554 LINC01250 HGNC:HGNC:49844|Ensembl:ENSG00000234423 +101927555 LOC101927555 - +101927556 LOC101927556 - +101927557 LOC101927557 Ensembl:ENSG00000266100 +101927558 LOC101927558 - +101927559 CEBPB-AS1 HGNC:HGNC:51226|Ensembl:ENSG00000277449 +101927560 LOC101927560 Ensembl:ENSG00000233008 +101927562 LOC101927562 - +101927565 LINC01267 HGNC:HGNC:50320|Ensembl:ENSG00000251576 +101927566 LOC101927566 - +101927571 LOC101927571 Ensembl:ENSG00000266850 +101927572 LOC101927572 - +101927573 LOC101927573 - +101927574 LINC01186 HGNC:HGNC:49573|Ensembl:ENSG00000236751 +101927575 LOC101927575 Ensembl:ENSG00000227463 +101927577 LINC01797 HGNC:HGNC:52587|Ensembl:ENSG00000237179 +101927579 DNM1P50 HGNC:HGNC:48499 +101927580 LINC02141 HGNC:HGNC:53001|Ensembl:ENSG00000261807 +101927581 CCDC182 HGNC:HGNC:49392|Ensembl:ENSG00000166329|Vega:OTTHUMG00000132063 +101927583 LOC101927583 - +101927584 LOC101927584 - +101927586 LINC01271 HGNC:HGNC:50327|Ensembl:ENSG00000233077 +101927587 LINC01725 HGNC:HGNC:52513|Ensembl:ENSG00000233008 +101927588 LOC101927588 Ensembl:ENSG00000214803 +101927590 LINC01166 HGNC:HGNC:49535|Ensembl:ENSG00000232903 +101927591 DPP10-AS3 HGNC:HGNC:40939|Ensembl:ENSG00000231538 +101927592 LINC02405 HGNC:HGNC:53333|Ensembl:ENSG00000249345 +101927595 LOC101927595 - +101927596 LOC101927596 Ensembl:ENSG00000231621 +101927597 NCK1-AS1 HGNC:HGNC:49645 +101927598 LOC101927598 - +101927599 ZNF529-AS1 HGNC:HGNC:51275|Ensembl:ENSG00000233527 +101927600 LOC101927600 - +101927601 GOLGA6L19 HGNC:HGNC:49416 +101927602 LOC101927602 - +101927603 LOC101927603 - +101927604 LOC101927604 Ensembl:ENSG00000223393 +101927605 LOC101927605 - +101927606 LINC01922 HGNC:HGNC:52741|Ensembl:ENSG00000259779 +101927608 LOC101927608 - +101927609 LOC101927609 - +101927610 LOC101927610 - +101927612 RNF139-AS1 HGNC:HGNC:48940|Ensembl:ENSG00000245149 +101927613 LOC101927613 - +101927615 LOC101927615 - +101927616 LINC02375 HGNC:HGNC:53297|Ensembl:ENSG00000256362 +101927619 LINC01923 HGNC:HGNC:52742 +101927620 LOC101927620 Ensembl:ENSG00000258731 +101927621 LINC01534 HGNC:HGNC:51281|Ensembl:ENSG00000225975 +101927623 LOC101927623 - +101927624 LINC01150 HGNC:HGNC:49469 +101927627 LOC101927627 - +101927629 LINC02165 HGNC:HGNC:53026 +101927630 LOC101927630 Ensembl:ENSG00000236039 +101927631 ADNP-AS1 HGNC:HGNC:51227|Ensembl:ENSG00000259456 +101927632 LOC101927632 - +101927635 LOC101927635 Ensembl:ENSG00000224292 +101927636 LOC101927636 Ensembl:ENSG00000251600 +101927637 LINC02411 HGNC:HGNC:53340|Ensembl:ENSG00000256022 +101927640 LOC101927640 - +101927641 LINC01877 HGNC:HGNC:52696|Ensembl:ENSG00000238217 +101927642 LINC01444 HGNC:HGNC:50769|Ensembl:ENSG00000264301 +101927646 LOC101927646 - +101927647 LOC101927647 - +101927650 LINC02126 HGNC:HGNC:52983|Ensembl:ENSG00000259847 +101927651 LINC01927 HGNC:HGNC:52749 +101927653 LINC02388 HGNC:HGNC:53315|Ensembl:ENSG00000257259 +101927655 ZASP - +101927657 LOC101927657 Ensembl:ENSG00000244791 +101927659 SMAD1-AS2 HGNC:HGNC:49381|Ensembl:ENSG00000250582 +101927661 LOC101927661 Ensembl:ENSG00000235885 +101927664 LOC101927664 - +101927666 LOC101927666 Ensembl:ENSG00000266290 +101927667 LINC01535 HGNC:HGNC:51282|Ensembl:ENSG00000226686 +101927668 LOC101927668 - +101927671 MIR202HG HGNC:HGNC:49402|Ensembl:ENSG00000166917 +101927673 LOC101927673 - +101927678 LINC01429 HGNC:HGNC:50741|Ensembl:ENSG00000227964 +101927682 CD81-AS1 HGNC:HGNC:49384|Ensembl:ENSG00000238184 +101927683 LINC01744 HGNC:HGNC:52532|Ensembl:ENSG00000236497 +101927685 HSFX4 HGNC:HGNC:52398|Ensembl:ENSG00000283463|Vega:OTTHUMG00000034359 +101927686 LINC02541 HGNC:HGNC:53574|Ensembl:ENSG00000230943 +101927687 LOC101927687 - +101927688 SEPT4-AS1 HGNC:HGNC:51345|Ensembl:ENSG00000264672 +101927689 LOC101927689 - +101927690 LOC101927690 Ensembl:ENSG00000258803 +101927691 LOC101927691 - +101927692 LOC101927692 Ensembl:ENSG00000228484 +101927693 LOC101927693 - +101927694 LINC02368 HGNC:HGNC:53291|Ensembl:ENSG00000256659 +101927697 LINC02227 HGNC:HGNC:53096|Ensembl:ENSG00000276778 +101927698 DSCAS HGNC:HGNC:51116|Ensembl:ENSG00000265888 +101927699 LOC101927699 - +101927700 LINC01524 HGNC:HGNC:51228|Ensembl:ENSG00000234948 +101927701 LINC01812 HGNC:HGNC:52616|Ensembl:ENSG00000237013 +101927702 LOC101927702 Ensembl:ENSG00000254718 +101927703 FOXCUT MIM:615976|HGNC:HGNC:50650 +101927704 MIR3663HG HGNC:HGNC:50676|Ensembl:ENSG00000234474 +101927708 LOC101927708 Ensembl:ENSG00000255367 +101927709 LOC101927709 - +101927711 LOC101927711 - +101927712 LOC101927712 - +101927715 LINC01029 HGNC:HGNC:49015 +101927717 GTF2IP8 HGNC:HGNC:51719 +101927718 DSG1-AS1 HGNC:HGNC:51115|Ensembl:ENSG00000266729 +101927720 ZNF793-AS1 HGNC:HGNC:51303 +101927721 LNCPRESS1 HGNC:HGNC:52746|Ensembl:ENSG00000232301 +101927722 LINC01644 HGNC:HGNC:52431|Ensembl:ENSG00000218357 +101927723 LOC101927723 - +101927726 BEAN1-AS1 HGNC:HGNC:51114|Ensembl:ENSG00000261656 +101927727 LOC101927727 Ensembl:ENSG00000262003 +101927728 LINC01476 HGNC:HGNC:51117|Ensembl:ENSG00000265313 +101927729 LINC02322 HGNC:HGNC:53241 +101927730 LOC101927730 - +101927735 TMEM132D-AS2 HGNC:HGNC:53324|Ensembl:ENSG00000256699 +101927740 LINC02202 HGNC:HGNC:53068|Ensembl:ENSG00000245812 +101927741 LOC101927741 - +101927745 LOC101927745 Ensembl:ENSG00000229425 +101927746 LOC101927746 - +101927750 ATP6V1B1-AS1 HGNC:HGNC:51118|Ensembl:ENSG00000239322 +101927751 LOC101927751 Ensembl:ENSG00000259583 +101927752 LOC101927752 Ensembl:ENSG00000253982 +101927755 LOC101927755 Ensembl:ENSG00000267302 +101927756 LOC101927756 - +101927759 LOC101927759 - +101927760 LOC101927760 - +101927761 TH2LCRR HGNC:HGNC:40495|Ensembl:ENSG00000223442 +101927762 LOC101927762 Ensembl:ENSG00000229869 +101927763 OLFM5P HGNC:HGNC:51927 +101927764 LOC101927764 - +101927765 LOC101927765 Ensembl:ENSG00000231663 +101927766 LINC01847 HGNC:HGNC:52662|Ensembl:ENSG00000253311 +101927768 HDAC2-AS2 HGNC:HGNC:43590|Ensembl:ENSG00000228624 +101927769 LOC101927769 Ensembl:ENSG00000226097 +101927770 LOC101927770 - +101927774 LINC00824 HGNC:HGNC:50281 +101927777 SATB1-AS1 HGNC:HGNC:50687 +101927780 LOC101927780 Ensembl:ENSG00000250548 +101927785 LOC101927785 - +101927786 LOC101927786 - +101927787 LOC101927787 Ensembl:ENSG00000228044 +101927788 LOC101927788 - +101927789 LOC101927789 - +101927790 LOC101927790 - +101927793 LOC101927793 Ensembl:ENSG00000259881 +101927795 LOC101927795 Ensembl:ENSG00000230408 +101927796 LINC01441 HGNC:HGNC:50763|Ensembl:ENSG00000224008 +101927797 MIR548XHG HGNC:HGNC:52006 +101927798 LOC101927798 Ensembl:ENSG00000253165 +101927801 LINC01823 HGNC:HGNC:52628 +101927802 LINC00368 HGNC:HGNC:42690 +101927808 CLSTN2-AS1 HGNC:HGNC:49095|Ensembl:ENSG00000250433 +101927809 LOC101927809 Ensembl:ENSG00000260552 +101927811 LOC101927811 Ensembl:ENSG00000271133 +101927813 HMMR-AS1 HGNC:HGNC:49149 +101927814 LOC101927814 - +101927815 LOC101927815 Ensembl:ENSG00000254319|Ensembl:ENSG00000277526 +101927817 LOC101927817 - +101927821 LINC01425 HGNC:HGNC:50733|Ensembl:ENSG00000233997 +101927822 LOC101927822 Ensembl:ENSG00000253593 +101927823 LOC101927823 - +101927824 LOC101927824 - +101927825 LOC101927825 - +101927827 LOC101927827 Ensembl:ENSG00000229311 +101927828 OVOL1-AS1 HGNC:HGNC:49319|Ensembl:ENSG00000255120 +101927829 LOC101927829 Ensembl:ENSG00000231304 +101927830 LOC101927830 - +101927832 PAQR9-AS1 HGNC:HGNC:50861|Ensembl:ENSG00000241570 +101927833 IFNL4P1 HGNC:HGNC:45090 +101927834 LOC101927834 - +101927835 LINC02143 HGNC:HGNC:53003|Ensembl:ENSG00000253236 +101927837 LOC101927837 Ensembl:ENSG00000270049 +101927839 LOC101927839 Ensembl:ENSG00000225084 +101927840 LOC101927840 - +101927843 LINC01687 HGNC:HGNC:52474|Ensembl:ENSG00000233215 +101927844 LOC101927844 - +101927845 LOC101927845 Ensembl:ENSG00000251218 +101927846 LOC101927846 - +101927847 LOC101927847 - +101927849 LINC02355 HGNC:HGNC:53277|Ensembl:ENSG00000248210 +101927851 LOC101927851 Ensembl:ENSG00000238005 +101927854 LOC101927854 - +101927855 LOC101927855 Ensembl:ENSG00000267131 +101927857 LOC101927857 - +101927858 LOC101927858 - +101927859 LOC101927859 - +101927861 LINC01293 HGNC:HGNC:50362 +101927862 CTB-178M22.2 Ensembl:ENSG00000253978 +101927863 LOC101927863 - +101927864 LOC101927864 - +101927865 LOC101927865 - +101927866 LINC02010 HGNC:HGNC:52846|Ensembl:ENSG00000242671 +101927868 GRK5-IT1 HGNC:HGNC:49478 +101927869 LINC01689 HGNC:HGNC:52476|Ensembl:ENSG00000224832 +101927870 LOC101927870 Ensembl:ENSG00000234715 +101927871 LOC101927871 - +101927872 LOC101927872 - +101927873 LINC01508 HGNC:HGNC:51190|Ensembl:ENSG00000231107 +101927876 LINC01654 HGNC:HGNC:52442|Ensembl:ENSG00000261781 +101927877 LOC101927877 Ensembl:ENSG00000265000 +101927879 LOC101927879 - +101927880 LOC101927880 - +101927881 LOC101927881 - +101927882 LOC101927882 - +101927884 LOC101927884 Ensembl:ENSG00000231172 +101927886 GBAT2 - +101927888 LOC101927888 - +101927889 LINC01153 HGNC:HGNC:49495|Ensembl:ENSG00000227143 +101927890 LOC101927890 - +101927891 PKN2-AS1 HGNC:HGNC:50597|Ensembl:ENSG00000237505 +101927895 LOC101927895 Ensembl:ENSG00000230424 +101927896 LOC101927896 - +101927897 LOC101927897 - +101927898 LOC101927898 - +101927900 LINC01477 HGNC:HGNC:51119|Ensembl:ENSG00000261715 +101927901 LINC02421 HGNC:HGNC:53351|Ensembl:ENSG00000255970 +101927902 LOC101927902 - +101927904 LOC101927904 - +101927905 LINC02449 HGNC:HGNC:53381|Ensembl:ENSG00000215241 +101927907 LOC101927907 Ensembl:ENSG00000234653 +101927908 LOC101927908 Ensembl:ENSG00000253469 +101927911 LOC101927911 Ensembl:ENSG00000262884 +101927913 LOC101927913 - +101927914 LOC101927914 Ensembl:ENSG00000234210 +101927915 LOC101927915 - +101927917 TUB-AS1 HGNC:HGNC:51120|Ensembl:ENSG00000248332 +101927919 LOC101927919 - +101927921 LINC01478 HGNC:HGNC:51121|Ensembl:ENSG00000267337 +101927922 LINC01479 HGNC:HGNC:51123|Ensembl:ENSG00000255772 +101927923 LOC101927923 - +101927924 LINC01856 HGNC:HGNC:52672|Ensembl:ENSG00000237574 +101927926 LINC01851 HGNC:HGNC:52667|Ensembl:ENSG00000233605 +101927931 LINC01480 HGNC:HGNC:51124|Ensembl:ENSG00000270164 +101927932 LOC101927932 - +101927934 LINC01843 HGNC:HGNC:52659|Ensembl:ENSG00000251169 +101927935 LOC101927935 - +101927936 LOC101927936 - +101927942 LOC101927942 - +101927943 LOC101927943 Ensembl:ENSG00000267414 +101927944 FAM53B-AS1 HGNC:HGNC:49499 +101927947 LOC101927947 - +101927948 LOC101927948 Ensembl:ENSG00000229494 +101927949 LOC101927949 - +101927950 LOC101927950 Ensembl:ENSG00000270174 +101927952 LOC101927952 - +101927953 C5orf66-AS1 HGNC:HGNC:49679|Ensembl:ENSG00000249082 +101927954 LOC101927954 - +101927957 LINC01572 HGNC:HGNC:51385|Ensembl:ENSG00000261008 +101927960 LOC101927960 - +101927961 LOC101927961 - +101927963 LOC101927963 - +101927964 LOC101927964 Ensembl:ENSG00000236990 +101927966 LOC101927966 - +101927967 LOC101927967 - +101927969 LOC101927969 - +101927971 LOC101927971 - +101927972 LOC101927972 Ensembl:ENSG00000269985 +101927973 LINC01695 HGNC:HGNC:52483|Ensembl:ENSG00000236532 +101927974 LOC101927974 - +101927975 LOC101927975 - +101927978 LOC101927978 - +101927979 LOC101927979 - +101927980 SLC14A2-AS1 HGNC:HGNC:51125 +101927983 EDRF1-AS1 HGNC:HGNC:49501|Ensembl:ENSG00000236991 +101927984 LOC101927984 - +101927987 LOC101927987 Ensembl:ENSG00000229385 +101927988 LINC01527 HGNC:HGNC:51266|Ensembl:ENSG00000224308 +101927989 LOC101927989 Ensembl:ENSG00000265778 +101927990 HRAT13 - +101927992 LINC01213 HGNC:HGNC:49648|Ensembl:ENSG00000244541 +101927993 LOC101927993 - +101927994 LINC01087 HGNC:HGNC:49144|Ensembl:ENSG00000224559 +101927995 LOC101927995 - +101927997 LOC101927997 - +101927999 LOC101927999 - +101928000 LOC101928000 Ensembl:ENSG00000234327 +101928001 PRKCA-AS1 HGNC:HGNC:51347 +101928002 LOC101928002 Ensembl:ENSG00000247131 +101928004 LOC101928004 - +101928005 LOC101928005 - +101928007 LOC101928007 - +101928008 LOC101928008 Ensembl:ENSG00000255476 +101928009 LOC101928009 Ensembl:ENSG00000229699 +101928010 LOC101928010 - +101928012 LOC101928012 Ensembl:ENSG00000223646 +101928014 LOC101928014 Ensembl:ENSG00000231990 +101928015 LINC01985 HGNC:HGNC:52816 +101928016 LOC101928016 - +101928017 UBXN10-AS1 HGNC:HGNC:41141|Ensembl:ENSG00000225986 +101928020 LOC101928020 - +101928021 LOC101928021 - +101928022 LINC01214 HGNC:HGNC:49650 +101928030 LOC101928030 - +101928031 LINC01809 HGNC:HGNC:52612|Ensembl:ENSG00000232548 +101928032 LOC101928032 - +101928033 CTD-2270F17.1 Ensembl:ENSG00000253647 +101928034 LOC101928034 - +101928035 LOC101928035 Ensembl:ENSG00000261404 +101928036 HRAT17 Ensembl:ENSG00000234520 +101928037 LOC101928037 - +101928039 LOC101928039 - +101928040 BARX1-AS1 HGNC:HGNC:50673 +101928041 LOC101928041 - +101928042 LOC101928042 - +101928043 LINC01635 HGNC:HGNC:52422|Ensembl:ENSG00000228397 +101928044 LOC101928044 - +101928045 LOC101928045 - +101928046 LOC101928046 - +101928047 LOC101928047 - +101928048 LOC101928048 - +101928049 LOC101928049 - +101928051 LOC101928051 - +101928052 LOC101928052 Ensembl:ENSG00000249419 +101928053 LOC101928053 Ensembl:ENSG00000246308 +101928055 LOC101928055 - +101928058 LOC101928058 - +101928059 LOC101928059 - +101928062 LINC01481 HGNC:HGNC:51126|Ensembl:ENSG00000257815 +101928063 LOC101928063 Ensembl:ENSG00000266921 +101928067 LINC01945 HGNC:HGNC:52769 +101928068 LOC101928068 - +101928069 LOC101928069 Ensembl:ENSG00000255517 +101928070 LOC101928070 - +101928075 LOC101928075 Ensembl:ENSG00000245466 +101928076 LOC101928076 - +101928077 LOC101928077 - +101928078 LOC101928078 - +101928079 SLC44A3-AS1 HGNC:HGNC:49057|Ensembl:ENSG00000224081 +101928080 LOC101928080 - +101928081 LOC101928081 - +101928084 LOC101928084 - +101928085 ERICH6-AS1 HGNC:HGNC:41205|Ensembl:ENSG00000240137 +101928087 LOC101928087 Ensembl:ENSG00000277332 +101928089 LOC101928089 - +101928092 LOC101928092 - +101928093 LOC101928093 - +101928095 LOC101928095 - +101928096 LOC101928096 - +101928098 LOC101928098 Ensembl:ENSG00000230427 +101928099 PCAT7 HGNC:HGNC:48824|Ensembl:ENSG00000231806 +101928100 LOC101928100 Ensembl:ENSG00000245648 +101928101 LOC101928101 - +101928103 LOC101928103 Ensembl:ENSG00000229267 +101928104 LINC01482 HGNC:HGNC:51128|Ensembl:ENSG00000267659 +101928105 LOC101928105 - +101928106 LINC02522 HGNC:HGNC:53541 +101928107 LOC101928107 Ensembl:ENSG00000226527 +101928108 LY6L HGNC:HGNC:52284|Ensembl:ENSG00000261667|Vega:OTTHUMG00000173037 +101928111 LOC101928111 Ensembl:ENSG00000222020 +101928113 ST3GAL5-AS1 HGNC:HGNC:51129 +101928114 LINC01811 HGNC:HGNC:52615 +101928118 LOC101928118 Ensembl:ENSG00000226026 +101928119 LOC101928119 - +101928120 LOC101928120 - +101928122 LINC01483 HGNC:HGNC:51130|Ensembl:ENSG00000227517 +101928123 LOC101928123 - +101928126 LOC101928126 - +101928128 LOC101928128 - +101928131 LOC101928131 - +101928132 LOC101928132 Ensembl:ENSG00000254438 +101928134 LOC101928134 Ensembl:ENSG00000259446 +101928135 LOC101928135 - +101928136 LINC01484 HGNC:HGNC:51136|Ensembl:ENSG00000253686 +101928137 LINC02444 HGNC:HGNC:53376|Ensembl:ENSG00000258123 +101928138 LINC01486 HGNC:HGNC:51137|Ensembl:ENSG00000256560 +101928140 LOC101928140 - +101928141 LINC01028 HGNC:HGNC:49014|Ensembl:ENSG00000267603 +101928142 AADACL2-AS1 HGNC:HGNC:50301 +101928143 LOC101928143 Ensembl:ENSG00000133961 +101928144 LOC101928144 Ensembl:ENSG00000264464 +101928145 LOC101928145 - +101928146 LOC101928146 - +101928147 C21orf140 HGNC:HGNC:39602|Ensembl:ENSG00000222018|Vega:OTTHUMG00000154291 +101928149 LOC101928149 - +101928150 LOC101928150 - +101928151 LINC01179 HGNC:HGNC:49556|Ensembl:ENSG00000249500 +101928152 LOC101928152 - +101928153 ITGA9-AS1 HGNC:HGNC:49668|Ensembl:ENSG00000235257 +101928154 LINC01485 HGNC:HGNC:51138 +101928156 LOC101928156 - +101928158 LAMA5-AS1 HGNC:HGNC:40334|Ensembl:ENSG00000228812 +101928160 LOC101928160 Ensembl:ENSG00000181135 +101928161 LOC101928161 Ensembl:ENSG00000226953 +101928162 LINC02366 HGNC:HGNC:53289|Ensembl:ENSG00000256888 +101928163 LOC101928163 - +101928165 CASC17 HGNC:HGNC:43911|Ensembl:ENSG00000260785 +101928166 LOC101928166 - +101928167 LINC01917 HGNC:HGNC:52736|Ensembl:ENSG00000260433 +101928168 LOC101928168 Ensembl:ENSG00000106069 +101928169 LINC01650 HGNC:HGNC:52437 +101928173 LINC01943 HGNC:HGNC:52767 +101928174 LOC101928174 Ensembl:ENSG00000250007 +101928176 LINC01411 HGNC:HGNC:50703|Ensembl:ENSG00000249306 +101928177 LOC101928177 - +101928180 LOC101928180 - +101928185 LOC101928185 Ensembl:ENSG00000233729 +101928188 LOC101928188 - +101928190 LINC01487 HGNC:HGNC:51139|Ensembl:ENSG00000241336 +101928191 LOC101928191 - +101928193 LOC101928193 - +101928195 LOC101928195 - +101928196 LOC101928196 - +101928200 MRGPRF-AS1 HGNC:HGNC:51140|Ensembl:ENSG00000256508 +101928201 LOC101928201 Ensembl:ENSG00000236513 +101928202 LOC101928202 - +101928203 LINC02125 HGNC:HGNC:52982|Ensembl:ENSG00000250514 +101928205 LINC02097 HGNC:HGNC:52948|Ensembl:ENSG00000226101 +101928208 LOC101928208 - +101928211 LOC101928211 - +101928212 LOC101928212 - +101928214 LOC101928214 - +101928215 LOC101928215 - +101928216 LOC101928216 - +101928217 LOC101928217 - +101928219 LOC101928219 - +101928222 LOC101928222 - +101928223 LINC01612 HGNC:HGNC:51837 +101928226 LOC101928226 - +101928227 LINC02345 HGNC:HGNC:53267|Ensembl:ENSG00000259225 +101928228 LOC101928228 - +101928230 LOC101928230 - +101928231 LOC101928231 - +101928232 LINC01280 HGNC:HGNC:50336 +101928233 LINC01671 HGNC:HGNC:52459|Ensembl:ENSG00000225431 +101928234 LOC101928234 - +101928235 CTB-41I6.1 - +101928236 LOC101928236 - +101928237 LOC101928237 - +101928238 LOC101928238 Ensembl:ENSG00000278611 +101928241 LINC01787 HGNC:HGNC:52576|Ensembl:ENSG00000231987 +101928242 LOC101928242 - +101928243 DARS-AS1 HGNC:HGNC:40170|Ensembl:ENSG00000231890 +101928244 TESC-AS1 HGNC:HGNC:51142 +101928247 LOC101928247 - +101928248 LINC01229 HGNC:HGNC:49682|Ensembl:ENSG00000260876 +101928249 LOC101928249 - +101928251 LOC101928251 Ensembl:ENSG00000264985 +101928253 LOC101928253 - +101928254 LOC101928254 Ensembl:ENSG00000219445 +101928255 LOC101928255 - +101928256 UBE2Q2P10 HGNC:HGNC:49518 +101928257 LOC101928257 - +101928259 PHKA1-AS1 HGNC:HGNC:40446|Ensembl:ENSG00000231944 +101928263 LOC101928263 - +101928264 LOC101928264 - +101928266 LOC101928266 Ensembl:ENSG00000262966 +101928268 LOC101928268 - +101928269 LOC101928269 - +101928270 LINC01708 HGNC:HGNC:52496|Ensembl:ENSG00000224445 +101928271 LOC101928271 Ensembl:ENSG00000236436 +101928272 LOC101928272 - +101928273 LOC101928273 - +101928274 LOC101928274 - +101928276 LINC01227 HGNC:HGNC:49680|Ensembl:ENSG00000260737 +101928277 LOC101928277 - +101928278 LOC101928278 - +101928279 LOC101928279 - +101928280 LINC02549 HGNC:HGNC:53584|Ensembl:ENSG00000226497 +101928283 LOC101928283 Ensembl:ENSG00000237764 +101928284 LOC101928284 - +101928287 LINC01285 HGNC:HGNC:50344|Ensembl:ENSG00000203650 +101928288 LINC02504 HGNC:HGNC:53493|Ensembl:ENSG00000248339 +101928290 PLBD1-AS1 HGNC:HGNC:51143|Ensembl:ENSG00000256751 +101928292 LINC01488 HGNC:HGNC:51144 +101928295 LOC101928295 Ensembl:ENSG00000268686 +101928296 LOC101928296 - +101928298 LOC101928298 Ensembl:ENSG00000224788 +101928300 LOC101928300 - +101928303 LOC101928303 Ensembl:ENSG00000236155 +101928304 LOC101928304 - +101928306 LOC101928306 - +101928307 LOC101928307 Ensembl:ENSG00000230910 +101928309 LINC02530 HGNC:HGNC:53556 +101928311 LINC01668 HGNC:HGNC:52456|Ensembl:ENSG00000283051 +101928314 LOC101928314 - +101928316 LOC101928316 - +101928317 LOC101928317 - +101928322 LOC101928322 Ensembl:ENSG00000270111 +101928323 LOC101928323 - +101928324 LOC101928324 - +101928326 LOC101928326 - +101928327 LINC01921 HGNC:HGNC:52740|Ensembl:ENSG00000223874 +101928331 LOC101928331 - +101928333 LOC101928333 Ensembl:ENSG00000236340 +101928334 LOC101928334 - +101928335 LOC101928335 Ensembl:ENSG00000236064 +101928336 LOC101928336 Ensembl:ENSG00000230392 +101928337 PTCSC2 HGNC:HGNC:44086 +101928338 LOC101928338 - +101928340 LINC01489 HGNC:HGNC:51145|Ensembl:ENSG00000255727 +101928343 LOC101928343 - +101928344 LOC101928344 - +101928345 PABPC1L2B-AS1 HGNC:HGNC:50345|Ensembl:ENSG00000226725 +101928346 LOC101928346 - +101928347 LOC101928347 - +101928350 LOC101928350 - +101928351 LOC101928351 - +101928352 LOC101928352 - +101928353 EVADR - +101928354 LOC101928354 - +101928355 LOC101928355 - +101928357 LOC101928357 - +101928358 LOC101928358 Ensembl:ENSG00000237863 +101928359 LOC101928359 - +101928361 LOC101928361 - +101928362 LOC101928362 - +101928363 EHD4-AS1 HGNC:HGNC:51418 +101928368 LOC101928368 - +101928369 LOC101928369 - +101928370 LOC101928370 - +101928371 LOC101928371 Ensembl:ENSG00000225420 +101928372 LOC101928372 Ensembl:ENSG00000198358 +101928373 LOC101928373 - +101928376 IL12A-AS1 HGNC:HGNC:49094|Ensembl:ENSG00000244040 +101928377 LOC101928377 - +101928378 PTOV1-AS2 HGNC:HGNC:51284 +101928380 LOC101928380 Ensembl:ENSG00000231963 +101928381 LOC101928381 - +101928383 LOC101928383 - +101928384 LOC101928384 - +101928385 LOC101928385 - +101928386 LOC101928386 Ensembl:ENSG00000232377 +101928387 LOC101928387 - +101928388 PLA2G4E-AS1 HGNC:HGNC:51419|Ensembl:ENSG00000246740 +101928389 LOC101928389 Ensembl:ENSG00000235834 +101928391 LOC101928391 - +101928392 LOC101928392 - +101928395 LOC101928395 - +101928397 LOC101928397 - +101928398 LOC101928398 - +101928399 LINC01679 HGNC:HGNC:52469|Ensembl:ENSG00000237989 +101928401 LOC101928401 Ensembl:ENSG00000233288 +101928402 LOC101928402 Ensembl:ENSG00000232412 +101928403 LOC101928403 Ensembl:ENSG00000234028 +101928404 LOC101928404 Ensembl:ENSG00000232892 +101928405 LINC02023 HGNC:HGNC:52858|Ensembl:ENSG00000239205 +101928406 LINC02543 HGNC:HGNC:53577 +101928409 LOC101928409 - +101928414 LOC101928414 Ensembl:ENSG00000259520 +101928415 LOC101928415 - +101928416 LOC101928416 Ensembl:ENSG00000255916 +101928417 LOC101928417 Ensembl:ENSG00000260832 +101928418 LOC101928418 Ensembl:ENSG00000227274 +101928419 LOC101928419 - +101928420 LINC01490 HGNC:HGNC:51146|Ensembl:ENSG00000257741 +101928421 LOC101928421 - +101928422 LOC101928422 - +101928423 LOC101928423 - +101928424 LOC101928424 Ensembl:ENSG00000255337 +101928425 LOC101928425 - +101928429 LOC101928429 - +101928433 LOC101928433 - +101928435 LINC01700 HGNC:HGNC:52488|Ensembl:ENSG00000232837 +101928436 LOC101928436 - +101928437 LOC101928437 - +101928438 LOC101928438 Ensembl:ENSG00000237461 +101928440 FBXO3-AS1 HGNC:HGNC:51147|Ensembl:ENSG00000254508 +101928441 LOC101928441 Ensembl:ENSG00000256321 +101928442 LINC01491 HGNC:HGNC:51148|Ensembl:ENSG00000259572 +101928443 LOC101928443 Ensembl:ENSG00000248844 +101928445 LOC101928445 Ensembl:ENSG00000244945 +101928446 LOC101928446 Ensembl:ENSG00000260862 +101928447 LOC101928447 - +101928448 C5orf67 HGNC:HGNC:51252|Ensembl:ENSG00000225940|Vega:OTTHUMG00000059482 +101928449 LINC02426 HGNC:HGNC:53357|Ensembl:ENSG00000257747 +101928450 LOC101928450 - +101928451 LOC101928451 - +101928453 LOC101928453 - +101928455 LINC01412 HGNC:HGNC:50704 +101928460 LINC01756 HGNC:HGNC:52545|Ensembl:ENSG00000230523 +101928461 LOC101928461 - +101928462 LOC101928462 - +101928463 LOC101928463 - +101928464 LOC101928464 Ensembl:ENSG00000219665 +101928465 LOC101928465 - +101928466 LOC101928466 - +101928469 MIR325HG HGNC:HGNC:50346|Ensembl:ENSG00000280870 +101928470 TMEM246-AS1 HGNC:HGNC:51191|Ensembl:ENSG00000225376 +101928471 SOX5-AS1 HGNC:HGNC:53311|Ensembl:ENSG00000256120 +101928472 LOC101928472 - +101928473 LOC101928473 - +101928474 LOC101928474 - +101928475 LOC101928475 Ensembl:ENSG00000232058 +101928476 LINC01676 HGNC:HGNC:52464|Ensembl:ENSG00000230768 +101928477 LOC101928477 - +101928478 LINC02269 HGNC:HGNC:53184 +101928483 NALT1 HGNC:HGNC:51192 +101928484 LINC01363 HGNC:HGNC:50598 +101928487 LOC101928487 - +101928489 LOC101928489 Ensembl:ENSG00000231652 +101928491 LOC101928491 - +101928492 OR2A1-AS1 HGNC:HGNC:49168 +101928495 LOC101928495 Ensembl:ENSG00000237208 +101928496 LINC01492 HGNC:HGNC:51149|Ensembl:ENSG00000225564 +101928499 LOC101928499 - +101928502 LOC101928502 - +101928504 LOC101928504 - +101928505 LOC101928505 - +101928507 LOC101928507 - +101928508 LOC101928508 - +101928509 LINC02268 HGNC:HGNC:53183|Ensembl:ENSG00000248174 +101928510 LOC101928510 - +101928512 LOC101928512 - +101928513 CATIP-AS1 HGNC:HGNC:41080|Ensembl:ENSG00000225062 +101928514 LINC02080 HGNC:HGNC:52928|Ensembl:ENSG00000267065 +101928516 LOC101928516 Ensembl:ENSG00000223786 +101928517 LOC101928517 Ensembl:ENSG00000269072 +101928519 LOC101928519 - +101928521 LOC101928521 Ensembl:ENSG00000242686 +101928523 LOC101928523 - +101928524 LOC101928524 - +101928525 LOC101928525 Ensembl:ENSG00000226706 +101928526 LOC101928526 - +101928527 PIGBOS1 HGNC:HGNC:50696|Ensembl:ENSG00000225973|Vega:OTTHUMG00000172653 +101928529 LOC101928529 - +101928530 LOC101928530 Ensembl:ENSG00000236617 +101928532 LOC101928532 - +101928535 LOC101928535 Ensembl:ENSG00000254811 +101928536 LINC01493 HGNC:HGNC:51150|Ensembl:ENSG00000254562 +101928537 LINC01494 HGNC:HGNC:51152|Ensembl:ENSG00000228135 +101928539 LINC02225 HGNC:HGNC:53094|Ensembl:ENSG00000249584 +101928540 LOC101928540 - +101928543 LOC101928543 - +101928545 SEPT7-AS1 HGNC:HGNC:51153 +101928548 LOC101928548 - +101928550 SMC2-AS1 HGNC:HGNC:50827|Ensembl:ENSG00000270332 +101928551 LOC101928551 - +101928553 LOC101928553 - +101928554 LOC101928554 - +101928555 LINC01537 HGNC:HGNC:51301|Ensembl:ENSG00000227467 +101928556 LOC101928556 - +101928557 LOC101928557 Ensembl:ENSG00000270159 +101928559 LINC01467 HGNC:HGNC:50911|Ensembl:ENSG00000258977 +101928561 LOC101928561 - +101928563 LOC101928563 - +101928565 LOC101928565 Ensembl:ENSG00000228697 +101928566 TBC1D3P6 HGNC:HGNC:43568 +101928567 LINC02087 HGNC:HGNC:52938|Ensembl:ENSG00000237057 +101928569 LINC02101 HGNC:HGNC:52956 +101928570 LOC101928570 - +101928571 ZNF649-AS1 HGNC:HGNC:51285|Ensembl:ENSG00000268095 +101928572 LOC101928572 - +101928573 LOC101928573 - +101928574 LOC101928574 - +101928576 LOC101928576 - +101928578 RAP2C-AS1 HGNC:HGNC:40957|Ensembl:ENSG00000232160 +101928580 P4HA3-AS1 HGNC:HGNC:53160|Ensembl:ENSG00000246211 +101928582 LOC101928582 - +101928583 LOC101928583 Ensembl:ENSG00000013297 +101928587 LOC101928587 - +101928589 LOC101928589 - +101928590 LOC101928590 Ensembl:ENSG00000249106 +101928591 LOC101928591 - +101928592 LOC101928592 - +101928595 LOC101928595 - +101928596 LOC101928596 Ensembl:ENSG00000237707 +101928597 LOC101928597 Ensembl:ENSG00000246394 +101928599 LINC02301 HGNC:HGNC:53220 +101928600 LINC02108 HGNC:HGNC:52963|Ensembl:ENSG00000250127 +101928601 MEI4 HGNC:HGNC:43638|Ensembl:ENSG00000269964|Vega:OTTHUMG00000153472 +101928602 LINC01775 HGNC:HGNC:52565|Ensembl:ENSG00000267201 +101928603 C6orf229 HGNC:HGNC:49394|Ensembl:ENSG00000260286|Vega:OTTHUMG00000177257 +101928604 ZBTB46-AS1 HGNC:HGNC:40753 +101928605 LOC101928605 - +101928607 TRPM2-AS HGNC:HGNC:50758 +101928608 LOC101928608 - +101928610 LOC101928610 - +101928611 LINC01413 HGNC:HGNC:50705 +101928612 HSPC324 Ensembl:ENSG00000228401 +101928614 LINC02189 HGNC:HGNC:53051|Ensembl:ENSG00000260026 +101928616 LINC00354 HGNC:HGNC:42672 +101928617 LOC101928617 - +101928618 LOC101928618 Ensembl:ENSG00000261184 +101928622 LOC101928622 Ensembl:ENSG00000250954 +101928625 LOC101928625 - +101928626 LOC101928626 Ensembl:ENSG00000230021 +101928627 LOC101928627 Ensembl:ENSG00000226484 +101928628 LOC101928628 - +101928630 SMIM15-AS1 HGNC:HGNC:41293 +101928631 LOC101928631 - +101928635 LOC101928635 - +101928636 LOC101928636 - +101928638 PRR31 HGNC:HGNC:18147 +101928646 ARNTL2-AS1 HGNC:HGNC:49892|Ensembl:ENSG00000245311 +101928649 CTC-338M12.4 - +101928650 LOC101928650 - +101928651 LOC101928651 Ensembl:ENSG00000248529 +101928656 LINC01099 HGNC:HGNC:49222|Ensembl:ENSG00000251504 +101928658 LOC101928658 - +101928659 LOC101928659 Ensembl:ENSG00000270006 +101928661 LOC101928661 Ensembl:ENSG00000237468 +101928663 LOC101928663 - +101928669 LOC101928669 - +101928671 LOC101928671 - +101928673 LOC101928673 Ensembl:ENSG00000203739 +101928674 LOC101928674 Ensembl:ENSG00000266970 +101928675 LOC101928675 - +101928677 ETDA HGNC:HGNC:53449 +101928678 LOC101928678 - +101928679 LINC02500 HGNC:HGNC:53488 +101928682 LOC101928682 Ensembl:ENSG00000261697 +101928684 LINC01209 HGNC:HGNC:49640|Ensembl:ENSG00000228308 +101928685 NACAP3 HGNC:HGNC:49490 +101928687 LINC01468 HGNC:HGNC:50913|Ensembl:ENSG00000231131 +101928688 LOC101928688 - +101928689 LINC01424 HGNC:HGNC:40558 +101928692 LOC101928692 - +101928694 LIPC-AS1 HGNC:HGNC:52294|Ensembl:ENSG00000259293 +101928696 LOC101928696 Ensembl:ENSG00000229531 +101928697 LOC101928697 - +101928698 LINC01070 HGNC:HGNC:49110 +101928700 LOC101928700 Ensembl:ENSG00000236795 +101928701 LOC101928701 - +101928704 LOC101928704 - +101928705 LOC101928705 - +101928707 LOC101928707 Ensembl:ENSG00000260219 +101928708 LOC101928708 Ensembl:ENSG00000261095 +101928710 LINC02081 HGNC:HGNC:52930|Ensembl:ENSG00000267123 +101928711 LOC101928711 - +101928715 TPT1P10 HGNC:HGNC:49301 +101928716 LOC101928716 - +101928718 LOC101928718 Ensembl:ENSG00000197852 +101928720 LINC01509 HGNC:HGNC:51193 +101928721 LOC101928721 - +101928722 LOC101928722 - +101928725 LOC101928725 Ensembl:ENSG00000245975 +101928728 LOC101928728 Ensembl:ENSG00000260063 +101928730 LOC101928730 - +101928731 LOC101928731 Ensembl:ENSG00000258274 +101928733 LOC101928733 Ensembl:ENSG00000228151 +101928734 WWC2-AS1 HGNC:HGNC:41041|Ensembl:ENSG00000251128 +101928735 LOC101928735 - +101928736 MIR762HG HGNC:HGNC:51386|Ensembl:ENSG00000260083 +101928737 LOC101928737 Ensembl:ENSG00000260750 +101928738 LINC01978 HGNC:HGNC:52806|Ensembl:ENSG00000262188 +101928739 LOC101928739 Ensembl:ENSG00000229102 +101928741 LINC02065 HGNC:HGNC:52910 +101928743 LOC101928743 - +101928744 LINC01450 HGNC:HGNC:50792|Ensembl:ENSG00000232458 +101928745 LL21NC02-21A1.1 - +101928748 LOC101928748 Ensembl:ENSG00000236461 +101928751 LINC01657 HGNC:HGNC:52445|Ensembl:ENSG00000224718 +101928752 LINC01043 HGNC:HGNC:49031|Ensembl:ENSG00000260343 +101928755 LOC101928755 - +101928760 LOC101928760 - +101928762 LOC101928762 - +101928764 LOC101928764 - +101928765 LINC01807 HGNC:HGNC:52610 +101928766 LINC01979 HGNC:HGNC:52807|Ensembl:ENSG00000262585 +101928767 LINC02328 HGNC:HGNC:53248 +101928768 LOC101928768 - +101928769 LINC02229 HGNC:HGNC:53098|Ensembl:ENSG00000250313 +101928770 LINC01526 HGNC:HGNC:51265|Ensembl:ENSG00000224995 +101928773 LINC01449 HGNC:HGNC:50791|Ensembl:ENSG00000224017 +101928775 LOC101928775 Ensembl:ENSG00000228714 +101928776 LINC01258 HGNC:HGNC:49898|Ensembl:ENSG00000249534 +101928778 LINC01741 HGNC:HGNC:52529|Ensembl:ENSG00000236720 +101928781 TMEM26-AS1 HGNC:HGNC:51209 +101928782 LOC101928782 Ensembl:ENSG00000224865 +101928784 RORA-AS1 HGNC:HGNC:51410|Ensembl:ENSG00000245534 +101928786 LOC101928786 - +101928788 ARL4AP5 HGNC:HGNC:52374 +101928790 PEX5L-AS2 HGNC:HGNC:41252|Ensembl:ENSG00000244302 +101928791 LOC101928791 Ensembl:ENSG00000258826 +101928794 MAST4-AS1 HGNC:HGNC:40865 +101928795 LINC01448 HGNC:HGNC:50790|Ensembl:ENSG00000238284 +101928796 LOC101928796 - +101928797 LOC101928797 Ensembl:ENSG00000233569 +101928804 LOC101928804 - +101928807 LOC101928807 - +101928808 LOC101928808 - +101928809 LOC101928809 Ensembl:ENSG00000245928 +101928812 LOC101928812 Ensembl:ENSG00000254427 +101928813 LOC101928813 - +101928815 LOC101928815 - +101928816 LOC101928816 - +101928817 LOC101928817 - +101928819 LOC101928819 - +101928820 LINC02535 HGNC:HGNC:53569|Ensembl:ENSG00000234155 +101928823 LOC101928823 Ensembl:ENSG00000254968 +101928824 LOC101928824 - +101928827 ELOCP33 HGNC:HGNC:49174 +101928832 LOC101928832 - +101928833 LOC101928833 - +101928834 LOC101928834 Ensembl:ENSG00000233968 +101928836 LOC101928836 - +101928837 LOC101928837 Ensembl:ENSG00000255100 +101928840 PWRN3 HGNC:HGNC:49131|Ensembl:ENSG00000260760 +101928841 LOC101928841 - +101928842 LOC101928842 - +101928844 LOC101928844 Ensembl:ENSG00000267709 +101928845 LINC01842 HGNC:HGNC:52656|Ensembl:ENSG00000267147 +101928846 HIPK1-AS1 HGNC:HGNC:50576|Ensembl:ENSG00000235527 +101928847 LOC101928847 Ensembl:ENSG00000247416 +101928849 LOC101928849 - +101928850 LOC101928850 Ensembl:ENSG00000259530 +101928851 LINC02380 HGNC:HGNC:53303|Ensembl:ENSG00000248505 +101928855 LOC101928855 Ensembl:ENSG00000262833 +101928856 LOC101928856 - +101928857 CTD-3080P12.3 Ensembl:ENSG00000249201 +101928858 LOC101928858 Ensembl:ENSG00000249364 +101928859 LOC101928859 - +101928861 LOC101928861 - +101928863 LOC101928863 - +101928864 LOC101928864 - +101928865 LOC101928865 Ensembl:ENSG00000251323 +101928866 LOC101928866 - +101928868 LOC101928868 - +101928869 GABRG3-AS1 HGNC:HGNC:40249|Ensembl:ENSG00000228740 +101928875 LOC101928875 - +101928877 LINC02436 HGNC:HGNC:53368 +101928879 LOC101928879 - +101928880 LINC02182 HGNC:HGNC:53044|Ensembl:ENSG00000260420 +101928881 LOC101928881 Ensembl:ENSG00000222001 +101928882 LOC101928882 Ensembl:ENSG00000145075 +101928885 LINC02198 HGNC:HGNC:53064 +101928886 LINC01864 HGNC:HGNC:52683|Ensembl:ENSG00000267522 +101928887 LOC101928887 Ensembl:ENSG00000224714 +101928891 LINC01637 HGNC:HGNC:52424|Ensembl:ENSG00000237476 +101928893 LOC101928893 - +101928894 LOC101928894 Ensembl:ENSG00000255314 +101928895 LINC01786 HGNC:HGNC:52575 +101928896 LOC101928896 Ensembl:ENSG00000255084 +101928902 LOC101928902 - +101928904 NPM1P30 HGNC:HGNC:45209 +101928906 LOC101928906 - +101928907 LOC101928907 - +101928909 LOC101928909 Ensembl:ENSG00000259163 +101928911 LOC101928911 - +101928912 LOC101928912 - +101928913 LINC01515 HGNC:HGNC:51210 +101928917 HSFX3 HGNC:HGNC:52395|Ensembl:ENSG00000283697|Vega:OTTHUMG00000022623 +101928919 LINC02489 HGNC:HGNC:53470 +101928922 LINC00463 HGNC:HGNC:42813|Ensembl:ENSG00000234056 +101928923 LOC101928923 - +101928924 LOC101928924 Ensembl:ENSG00000249295 +101928926 LOC101928926 - +101928929 LOC101928929 - +101928931 SEMA3B-AS1 HGNC:HGNC:49096|Ensembl:ENSG00000232352 +101928932 LOC101928932 Ensembl:ENSG00000237419 +101928933 LOC101928933 - +101928936 LOC101928936 - +101928937 LOC101928937 Ensembl:ENSG00000258039 +101928940 LOC101928940 Ensembl:ENSG00000256195 +101928941 RHOXF1P1 MIM:300973|HGNC:HGNC:51580|Ensembl:ENSG00000234493 +101928942 LOC101928942 Ensembl:ENSG00000251059 +101928943 LOC101928943 Ensembl:ENSG00000256746 +101928944 LOC101928944 Ensembl:ENSG00000255178 +101928945 LOC101928945 - +101928947 LOC101928947 - +101928948 LOC101928948 - +101928952 LOC101928952 - +101928953 LOC101928953 - +101928957 LOC101928957 - +101928959 LOC101928959 - +101928960 LOC101928960 - +101928961 LOC101928961 - +101928963 LOC101928963 - +101928969 RHOXF1-AS1 HGNC:HGNC:51582|Ensembl:ENSG00000258545 +101928971 LINC01262 HGNC:HGNC:50275|Ensembl:ENSG00000250739 +101928972 LOC101928972 - +101928973 LINC01732 HGNC:HGNC:52520|Ensembl:ENSG00000237292 +101928977 LOC101928977 - +101928978 LOC101928978 Ensembl:ENSG00000250546 +101928979 LINC01719 HGNC:HGNC:52506|Ensembl:ENSG00000233396 +101928982 LOC101928982 Ensembl:ENSG00000267421 +101928985 LOC101928985 - +101928988 LOC101928988 Ensembl:ENSG00000259351 +101928989 MIR4300HG HGNC:HGNC:52003|Ensembl:ENSG00000245832 +101928991 CCDC92B HGNC:HGNC:52279 +101928992 LINC02069 HGNC:HGNC:52915|Ensembl:ENSG00000229433 +101928993 LOC101928993 - +101928994 LOC101928994 Ensembl:ENSG00000229261 +101928995 LINC01649 HGNC:HGNC:52436|Ensembl:ENSG00000228127 +101928999 IQCF5-AS1 HGNC:HGNC:41297|Ensembl:ENSG00000235455 +101929000 LOC101929000 - +101929002 LINC02287 HGNC:HGNC:53204|Ensembl:ENSG00000258499 +101929003 LOC101929003 - +101929004 LOC101929004 - +101929006 LOC101929006 Ensembl:ENSG00000232505 +101929007 LOC101929007 - +101929008 GTF2IP13 HGNC:HGNC:51725 +101929010 SIRPG-AS1 HGNC:HGNC:51229|Ensembl:ENSG00000237914 +101929011 LOC101929011 Ensembl:ENSG00000237937 +101929013 LOC101929013 - +101929014 LOC101929014 - +101929018 LOC101929018 - +101929019 LINC02270 HGNC:HGNC:53185|Ensembl:ENSG00000251210 +101929021 LOC101929021 - +101929022 LOC101929022 - +101929023 LINC01762 HGNC:HGNC:52552|Ensembl:ENSG00000233154 +101929025 LINC01516 HGNC:HGNC:51211|Ensembl:ENSG00000231422 +101929026 ZACNP1 HGNC:HGNC:51915 +101929027 LINC02387 HGNC:HGNC:53313 +101929028 LOC101929028 - +101929031 LOC101929031 - +101929034 LINC02116 HGNC:HGNC:52971|Ensembl:ENSG00000250417 +101929036 LOC101929036 - +101929043 LOC101929043 - +101929045 LOC101929045 - +101929048 LOC101929048 - +101929050 LOC101929050 - +101929052 LINC00836 HGNC:HGNC:44915|Ensembl:ENSG00000280809 +101929053 LOC101929053 - +101929054 LOC101929054 Ensembl:ENSG00000243224 +101929056 LOC101929056 - +101929057 LOC101929057 - +101929058 LOC101929058 Ensembl:ENSG00000257860 +101929059 ZIM2-AS1 HGNC:HGNC:51304|Ensembl:ENSG00000269793 +101929060 LOC101929060 - +101929064 LOC101929064 Ensembl:ENSG00000250062 +101929066 LOC101929066 Ensembl:ENSG00000245281 +101929069 LINC01633 HGNC:HGNC:52420|Ensembl:ENSG00000260976 +101929071 LINC01182 HGNC:HGNC:49564|Ensembl:ENSG00000250634 +101929072 LOC101929072 - +101929073 LOC101929073 Ensembl:ENSG00000226304 +101929074 PIK3CD-AS2 HGNC:HGNC:51334|Ensembl:ENSG00000231789 +101929076 LOC101929076 Ensembl:ENSG00000245719 +101929077 LINC02334 HGNC:HGNC:53254 +101929079 LOC101929079 - +101929080 LINC02292 HGNC:HGNC:53208|Ensembl:ENSG00000258630 +101929081 CTD-2194D22.4 Ensembl:ENSG00000249326 +101929082 LINC01333 HGNC:HGNC:50539|Ensembl:ENSG00000249343 +101929083 CASC6 HGNC:HGNC:49076 +101929084 LINC02401 HGNC:HGNC:53328|Ensembl:ENSG00000257762 +101929086 LINC01447 HGNC:HGNC:50783|Ensembl:ENSG00000236078 +101929087 LOC101929087 - +101929088 LOC101929088 - +101929089 LOC101929089 Ensembl:ENSG00000255435 +101929091 LOC101929091 - +101929093 LINC01350 HGNC:HGNC:50575|Ensembl:ENSG00000228309 +101929095 LOC101929095 Ensembl:ENSG00000249252 +101929097 LOC101929097 - +101929098 LOC101929098 - +101929099 LOC101929099 Ensembl:ENSG00000236137 +101929104 LOC101929104 - +101929105 LOC101929105 - +101929106 LOC101929106 Ensembl:ENSG00000198491 +101929107 LOC101929107 - +101929109 LOC101929109 Ensembl:ENSG00000249713 +101929110 CASC18 HGNC:HGNC:49463|Ensembl:ENSG00000257859 +101929111 LINC01149 HGNC:HGNC:39757 +101929114 LOC101929114 - +101929116 LOC101929116 Ensembl:ENSG00000228392 +101929117 LOC101929117 - +101929120 LINC01351 HGNC:HGNC:50577 +101929121 LINC00437 HGNC:HGNC:42772 +101929122 LOC101929122 - +101929123 LINC02493 HGNC:HGNC:53477|Ensembl:ENSG00000250819 +101929124 LOC101929124 Ensembl:ENSG00000260599 +101929125 LINC01730 HGNC:HGNC:52518|Ensembl:ENSG00000275491 +101929127 PGM5P3-AS1 HGNC:HGNC:51194|Ensembl:ENSG00000277631 +101929128 LOC101929128 Ensembl:ENSG00000248538 +101929129 LOC101929129 - +101929130 LOC101929130 Ensembl:ENSG00000283175 +101929134 LOC101929134 Ensembl:ENSG00000138641 +101929135 LOC101929135 - +101929140 LOC101929140 Ensembl:ENSG00000278390 +101929141 LOC101929141 - +101929142 LOC101929142 - +101929144 LINC01858 HGNC:HGNC:52676|Ensembl:ENSG00000261615 +101929145 PPP3CB-AS1 HGNC:HGNC:50750|Ensembl:ENSG00000221817 +101929147 LOC101929147 Ensembl:ENSG00000231365 +101929148 LOC101929148 Ensembl:ENSG00000235059 +101929151 LINC02204 HGNC:HGNC:53070|Ensembl:ENSG00000280639 +101929152 P3H2-AS1 HGNC:HGNC:40886|Ensembl:ENSG00000225764 +101929153 LINC02114 HGNC:HGNC:52968|Ensembl:ENSG00000249521 +101929154 LOC101929154 - +101929157 PGM5P3 HGNC:HGNC:49604 +101929159 LOC101929159 Ensembl:ENSG00000241933 +101929160 LOC101929160 - +101929161 LOC101929161 - +101929162 LOC101929162 Ensembl:ENSG00000258136 +101929163 LOC101929163 Ensembl:ENSG00000277427 +101929164 LINC01859 HGNC:HGNC:52677|Ensembl:ENSG00000261558 +101929165 LOC101929165 - +101929172 LOC101929172 Ensembl:ENSG00000254334 +101929173 THSD4-AS2 HGNC:HGNC:51421 +101929174 LOC101929174 - +101929176 CTD-2297D10.2 - +101929178 LOC101929178 - +101929179 LINC01388 HGNC:HGNC:50660 +101929180 LOC101929180 - +101929181 LINC01647 HGNC:HGNC:52434|Ensembl:ENSG00000235643 +101929184 LINC01031 HGNC:HGNC:49017|Ensembl:ENSG00000232077 +101929185 LOC101929185 - +101929188 LOC101929188 - +101929191 LINCR-0001 Ensembl:ENSG00000253641 +101929194 LNCPRESS2 HGNC:HGNC:52747 +101929196 THSD4-AS1 HGNC:HGNC:51420 +101929198 ATP13A4-AS1 HGNC:HGNC:41095 +101929199 LINC02261 HGNC:HGNC:53173|Ensembl:ENSG00000249699 +101929200 LOC101929200 - +101929201 LOC101929201 - +101929202 MKX-AS1 HGNC:HGNC:50686 +101929203 RNFT1P3 HGNC:HGNC:44389 +101929204 LOC101929204 - +101929207 LINC01729 HGNC:HGNC:52517|Ensembl:ENSG00000225640 +101929208 LOC101929208 - +101929210 LOC101929210 Ensembl:ENSG00000246541 +101929212 SMIM2-AS1 HGNC:HGNC:42674|Ensembl:ENSG00000227258 +101929215 CTD-2201I18.1 Ensembl:ENSG00000249825 +101929216 LOC101929216 - +101929217 LOC101929217 Ensembl:ENSG00000253455 +101929218 LINC01517 HGNC:HGNC:51212 +101929221 C15orf59-AS1 HGNC:HGNC:51422 +101929222 DISC1FP1 HGNC:HGNC:33625|Ensembl:ENSG00000261645 +101929224 LOC101929224 Ensembl:ENSG00000260088 +101929225 MCM8-AS1 HGNC:HGNC:51230|Ensembl:ENSG00000278719 +101929227 LOC101929227 Ensembl:ENSG00000250493 +101929229 LOC101929229 - +101929230 LOC101929230 - +101929231 LOC101929231 Ensembl:ENSG00000231969 +101929232 LOC101929232 - +101929234 LOC101929234 - +101929235 LOC101929235 - +101929237 LOC101929237 Ensembl:ENSG00000248738 +101929238 C3orf67-AS1 HGNC:HGNC:41063|Ensembl:ENSG00000242428 +101929239 PACRG-AS2 HGNC:HGNC:40871|Ensembl:ENSG00000225437 +101929240 LOC101929240 Ensembl:ENSG00000265298 +101929241 LINC02325 HGNC:HGNC:53245|Ensembl:ENSG00000246084 +101929243 LOC101929243 Ensembl:ENSG00000272288 +101929244 CASC20 HGNC:HGNC:49477|Ensembl:ENSG00000229876 +101929247 LINC01231 HGNC:HGNC:49688 +101929248 LOC101929248 - +101929251 LOC101929251 - +101929254 LRRC37A12P HGNC:HGNC:43816 +101929255 LOC101929255 - +101929256 LOC101929256 - +101929258 LOC101929258 - +101929259 LOC101929259 - +101929260 LINC01920 HGNC:HGNC:52738|Ensembl:ENSG00000236049 +101929261 LINC02123 HGNC:HGNC:52980|Ensembl:ENSG00000250668 +101929265 LINC01428 HGNC:HGNC:50738|Ensembl:ENSG00000228888 +101929268 LOC101929268 Ensembl:ENSG00000253608 +101929269 LOC101929269 Ensembl:ENSG00000254839 +101929270 LOC101929270 - +101929272 LOC101929272 - +101929278 LOC101929278 - +101929279 LOC101929279 - +101929280 LOC101929280 - +101929282 LOC101929282 Ensembl:ENSG00000224048 +101929284 LINC02199 HGNC:HGNC:53065 +101929285 LOC101929285 - +101929286 KCNMA1-AS3 HGNC:HGNC:51215 +101929288 LINC01751 HGNC:HGNC:52539|Ensembl:ENSG00000261249 +101929289 LOC101929289 - +101929290 LOC101929290 - +101929291 LOC101929291 - +101929293 PTGES3P2 HGNC:HGNC:43822 +101929294 LOC101929294 - +101929295 LOC101929295 Ensembl:ENSG00000245552 +101929297 LOC101929297 Ensembl:ENSG00000233365 +101929298 LOC101929298 - +101929302 RFX3-AS1 HGNC:HGNC:51197|Ensembl:ENSG00000232104 +101929305 LOC101929305 - +101929307 LOC101929307 - +101929308 LOC101929308 - +101929309 LOC101929309 - +101929310 KCNMA1-AS2 HGNC:HGNC:51214|Ensembl:ENSG00000225497 +101929312 LINC01706 HGNC:HGNC:52494 +101929314 LOC101929314 - +101929315 LOC101929315 Ensembl:ENSG00000253643 +101929316 LOC101929316 - +101929319 LOC101929319 - +101929320 LOC101929320 - +101929321 LOC101929321 - +101929322 LOC101929322 - +101929326 LOC101929326 - +101929328 KCNMA1-AS1 HGNC:HGNC:51213|Ensembl:ENSG00000236467 +101929329 LAMP5-AS1 HGNC:HGNC:40754|Ensembl:ENSG00000225988 +101929331 LOC101929331 Ensembl:ENSG00000224307 +101929333 LOC101929333 Ensembl:ENSG00000260103 +101929335 ADAMTS9-AS1 HGNC:HGNC:40625|Ensembl:ENSG00000241158 +101929337 LINC02037 HGNC:HGNC:52877|Ensembl:ENSG00000238097 +101929338 SEMA5A-AS1 HGNC:HGNC:52973|Ensembl:ENSG00000251370 +101929340 LOC101929340 Ensembl:ENSG00000250073 +101929341 LOC101929341 Ensembl:ENSG00000253551 +101929343 LOC101929343 - +101929344 LINC01198 HGNC:HGNC:49598 +101929347 LOC101929347 - +101929348 LOC101929348 - +101929349 LOC101929349 - +101929350 LINC01665 HGNC:HGNC:52453|Ensembl:ENSG00000235343 +101929351 CDC37L1-AS1 HGNC:HGNC:49735|Ensembl:ENSG00000273061 +101929352 LOC101929352 - +101929353 LOC101929353 Ensembl:ENSG00000249710 +101929355 LOC101929355 - +101929356 LOC101929356 - +101929357 HP09053 - +101929359 LOC101929359 - +101929360 LOC101929360 - +101929367 LOC101929367 - +101929371 LOC101929371 - +101929372 LOC101929372 - +101929373 LOC101929373 - +101929374 LINC01659 HGNC:HGNC:52447|Ensembl:ENSG00000234928 +101929378 LINC01876 HGNC:HGNC:52695|Ensembl:ENSG00000226383 +101929380 LOC101929380 - +101929384 LOC101929384 Ensembl:ENSG00000256577 +101929386 LOC101929386 - +101929387 LMF1-AS1 HGNC:HGNC:50469|Ensembl:ENSG00000260439 +101929388 LOC101929388 - +101929390 LINC01247 HGNC:HGNC:49841|Ensembl:ENSG00000227007 +101929395 LINC01752 HGNC:HGNC:52540|Ensembl:ENSG00000224961 +101929397 LINC01518 HGNC:HGNC:51216 +101929398 LOC101929398 - +101929400 LOC101929400 - +101929402 EXTL3-AS1 HGNC:HGNC:27985|Ensembl:ENSG00000246339 +101929406 LINC01648 HGNC:HGNC:52435|Ensembl:ENSG00000233399 +101929407 PTPRD-AS1 HGNC:HGNC:49753 +101929408 LOC101929408 - +101929410 SUCLA2-AS1 HGNC:HGNC:39965 +101929411 LOC101929411 - +101929412 LINC02212 HGNC:HGNC:53079|Ensembl:ENSG00000249396 +101929413 LOC101929413 Ensembl:ENSG00000232900 +101929415 LOC101929415 Ensembl:ENSG00000254254 +101929418 LOC101929418 - +101929420 LOC101929420 Ensembl:ENSG00000234647 +101929422 LINC02285 HGNC:HGNC:53202|Ensembl:ENSG00000259004 +101929423 MEF2C-AS1 HGNC:HGNC:48908|Ensembl:ENSG00000248309 +101929425 BTBD9-AS1 HGNC:HGNC:40959 +101929426 LOC101929426 - +101929427 LOC101929427 Ensembl:ENSG00000254607 +101929428 PTPRD-AS2 HGNC:HGNC:49754|Ensembl:ENSG00000226717 +101929431 LOC101929431 - +101929432 LOC101929432 - +101929437 PRRX2-AS1 HGNC:HGNC:50684|Ensembl:ENSG00000236024 +101929439 LOC101929439 Ensembl:ENSG00000259422 +101929440 LOC101929440 - +101929441 LOC101929441 Ensembl:ENSG00000230550 +101929444 LOC101929444 - +101929445 LOC101929445 Ensembl:ENSG00000234944 +101929446 LOC101929446 - +101929447 LOC101929447 - +101929448 LINC02428 HGNC:HGNC:53359|Ensembl:ENSG00000248740 +101929450 LINC02099 HGNC:HGNC:52953|Ensembl:ENSG00000253490 +101929451 LOC101929451 - +101929452 LOC101929452 Ensembl:ENSG00000223884 +101929454 LINC02149 HGNC:HGNC:53010 +101929457 LOC101929457 Ensembl:ENSG00000259362 +101929459 LOC101929459 - +101929460 LOC101929460 Ensembl:ENSG00000229720 +101929464 LOC101929464 Ensembl:ENSG00000233246 +101929467 LURAP1L-AS1 HGNC:HGNC:49761|Ensembl:ENSG00000235448 +101929468 CXXC4-AS1 HGNC:HGNC:41054|Ensembl:ENSG00000245384 +101929469 LOC101929469 Ensembl:ENSG00000283297|Vega:OTTHUMG00000191716 +101929470 LOC101929470 Ensembl:ENSG00000248964 +101929471 HINT2P1 HGNC:HGNC:50311 +101929472 CTD-2350J17.1 - +101929473 LOC101929473 Ensembl:ENSG00000255087 +101929475 LOC101929475 - +101929476 LINC01698 HGNC:HGNC:52486 +101929478 LINGO1-AS2 HGNC:HGNC:51423|Ensembl:ENSG00000259281 +101929479 LOC101929479 Ensembl:ENSG00000229212 +101929480 LOC101929480 - +101929484 LINC01615 HGNC:HGNC:51898|Ensembl:ENSG00000223485 +101929485 LOC101929485 - +101929486 LINC01722 HGNC:HGNC:52510|Ensembl:ENSG00000233048 +101929488 LOC101929488 Ensembl:ENSG00000253871 +101929490 LOC101929490 - +101929492 LOC101929492 - +101929494 LOC101929494 Ensembl:ENSG00000276170 +101929495 LINC01339 HGNC:HGNC:50549 +101929497 LOC101929497 Ensembl:ENSG00000273409 +101929498 LOC101929498 - +101929504 LINC02544 HGNC:HGNC:53578|Ensembl:ENSG00000261039 +101929505 LINC02150 HGNC:HGNC:53012|Ensembl:ENSG00000248150 +101929506 LOC101929506 - +101929507 LOC101929507 - +101929510 LOC101929510 - +101929511 LINC01970 HGNC:HGNC:52796|Ensembl:ENSG00000265692 +101929512 LOC101929512 - +101929516 LOC101929516 Ensembl:ENSG00000228060 +101929517 LOC101929517 Ensembl:ENSG00000254588 +101929518 LOC101929518 - +101929520 LINC00993 HGNC:HGNC:48948|Ensembl:ENSG00000235687 +101929523 LOC101929523 Ensembl:ENSG00000226445 +101929524 LOC101929524 Ensembl:ENSG00000246214 +101929526 LOC101929526 Ensembl:ENSG00000233993 +101929527 LOC101929527 - +101929528 LOC101929528 Ensembl:ENSG00000253281 +101929529 LOC101929529 Ensembl:ENSG00000251175 +101929530 FANCD2P2 HGNC:HGNC:44488 +101929531 LINC01871 HGNC:HGNC:52690 +101929532 LOC101929532 Ensembl:ENSG00000236841 +101929534 LOC101929534 - +101929535 LOC101929535 - +101929536 LOC101929536 Ensembl:ENSG00000261798 +101929538 LOC101929538 Ensembl:ENSG00000245008 +101929539 LINC01422 HGNC:HGNC:50728|Ensembl:ENSG00000235271 +101929540 LOC101929540 - +101929541 LOC101929541 Ensembl:ENSG00000226251 +101929542 LOC101929542 - +101929544 LINC02217 HGNC:HGNC:53084|Ensembl:ENSG00000248455 +101929547 LOC101929547 - +101929548 FOCAD-AS1 HGNC:HGNC:49789|Ensembl:ENSG00000227071 +101929549 LOC101929549 Ensembl:ENSG00000255474 +101929550 LOC101929550 - +101929551 LOC101929551 Ensembl:ENSG00000226506 +101929552 LOC101929552 Ensembl:ENSG00000263063 +101929554 LOC101929554 - +101929555 LOC101929555 - +101929557 LINC01395 HGNC:HGNC:50674|Ensembl:ENSG00000281097 +101929559 LINC00211 HGNC:HGNC:37459|Ensembl:ENSG00000237803 +101929560 LOC101929560 - +101929563 LOC101929563 Ensembl:ENSG00000283982 +101929565 LINC01740 HGNC:HGNC:52528|Ensembl:ENSG00000228067 +101929566 LOC101929566 - +101929567 LINC01814 HGNC:HGNC:52618|Ensembl:ENSG00000236008 +101929570 LOC101929570 Ensembl:ENSG00000237750 +101929572 LOC101929572 Ensembl:ENSG00000276888 +101929574 LOC101929574 Ensembl:ENSG00000226659 +101929575 LOC101929575 - +101929577 LOC101929577 Ensembl:ENSG00000249635 +101929578 LOC101929578 - +101929579 LOC101929579 - +101929580 GTF2IP23 HGNC:HGNC:51735 +101929581 MZT1P2 HGNC:HGNC:50606 +101929582 LINC01241 HGNC:HGNC:49804|Ensembl:ENSG00000236306 +101929583 LOC101929583 - +101929584 LINC02443 HGNC:HGNC:53375|Ensembl:ENSG00000256115 +101929586 LOC101929586 Ensembl:ENSG00000259175 +101929589 RPL7P61 HGNC:HGNC:49217 +101929590 NRG3-AS1 HGNC:HGNC:31429|Ensembl:ENSG00000225738 +101929591 KIZ-AS1 HGNC:HGNC:51231|Ensembl:ENSG00000232712 +101929592 LOC101929592 Ensembl:ENSG00000229444 +101929594 LOC101929594 - +101929595 LOC101929595 Ensembl:ENSG00000245293 +101929596 LOC101929596 - +101929598 LOC101929598 - +101929599 LOC101929599 - +101929601 LOC101929601 - +101929602 IFT74-AS1 HGNC:HGNC:49806|Ensembl:ENSG00000234676 +101929607 LINC01990 HGNC:HGNC:52822|Ensembl:ENSG00000273125 +101929608 LINC01726 HGNC:HGNC:52514|Ensembl:ENSG00000280350 +101929609 LOC101929609 - +101929613 LOC101929613 - +101929614 LOC101929614 - +101929617 LOC101929617 - +101929620 LINC01243 HGNC:HGNC:49814|Ensembl:ENSG00000260720 +101929621 LOC101929621 - +101929622 LOC101929622 - +101929623 LINC01215 HGNC:HGNC:49651|Ensembl:ENSG00000271856 +101929624 LINC01519 HGNC:HGNC:51217|Ensembl:ENSG00000237267 +101929625 LINC01727 HGNC:HGNC:52515 +101929626 LOC101929626 Ensembl:ENSG00000227857 +101929627 LOC101929627 - +101929628 LOC101929628 - +101929631 LINC01653 HGNC:HGNC:52441|Ensembl:ENSG00000232100 +101929633 LOC101929633 - +101929634 LINC02280 HGNC:HGNC:53196|Ensembl:ENSG00000260792 +101929637 NTM-AS1 HGNC:HGNC:32293|Ensembl:ENSG00000224795 +101929638 LOC101929638 - +101929639 B4GALT1-AS1 HGNC:HGNC:49910|Ensembl:ENSG00000233554 +101929643 LOC101929643 - +101929645 LOC101929645 - +101929646 LOC101929646 - +101929650 LOC101929650 - +101929651 LINC01398 HGNC:HGNC:50678|Ensembl:ENSG00000224863 +101929653 LOC101929653 Ensembl:ENSG00000237654 +101929655 TMC3-AS1 HGNC:HGNC:51424 +101929657 LOC101929657 Ensembl:ENSG00000273523 +101929660 LINC02109 HGNC:HGNC:52964 +101929662 LOC101929662 Ensembl:ENSG00000224504 +101929663 LINC01427 HGNC:HGNC:50737|Ensembl:ENSG00000225321 +101929664 HORMAD2-AS1 HGNC:HGNC:50729 +101929665 UBE2R2-AS1 HGNC:HGNC:49911 +101929667 LOC101929667 - +101929669 GEMIN2P1 HGNC:HGNC:49561 +101929670 LOC101929670 - +101929679 LOC101929679 - +101929680 LOC101929680 Ensembl:ENSG00000236107 +101929681 LINC02064 HGNC:HGNC:52909 +101929684 LINC01520 HGNC:HGNC:51218|Ensembl:ENSG00000230962 +101929685 LINC01384 HGNC:HGNC:50656|Ensembl:ENSG00000237396 +101929688 LINC01251 HGNC:HGNC:49845|Ensembl:ENSG00000233776 +101929690 LINC01583 HGNC:HGNC:51425|Ensembl:ENSG00000259518 +101929691 LOC101929691 - +101929692 LOC101929692 - +101929693 RARA-AS1 HGNC:HGNC:49577|Ensembl:ENSG00000265666 +101929694 LINC02042 HGNC:HGNC:52882|Ensembl:ENSG00000240893 +101929696 PSD2-AS1 HGNC:HGNC:52765|Ensembl:ENSG00000249131 +101929697 LINC01983 HGNC:HGNC:52813 +101929698 LOC101929698 Ensembl:ENSG00000277301 +101929700 LINC01794 HGNC:HGNC:52584 +101929701 LINC01584 HGNC:HGNC:51426|Ensembl:ENSG00000260477 +101929703 LOC101929703 - +101929704 LOC101929704 Ensembl:ENSG00000272323 +101929705 LOC101929705 Ensembl:ENSG00000237686 +101929707 LOC101929707 - +101929709 LOC101929709 Ensembl:ENSG00000251136 +101929710 LOC101929710 Ensembl:ENSG00000251314 +101929715 LOC101929715 - +101929716 ARMC2-AS1 HGNC:HGNC:41008 +101929717 LINC02044 HGNC:HGNC:52884|Ensembl:ENSG00000243795 +101929718 LOC101929718 Ensembl:ENSG00000258471 +101929719 LOC101929719 Ensembl:ENSG00000254363 +101929721 LOC101929721 Ensembl:ENSG00000230114 +101929723 LINC01914 HGNC:HGNC:52733|Ensembl:ENSG00000234362 +101929726 MYMX HGNC:HGNC:52391|Ensembl:ENSG00000262179|Vega:OTTHUMG00000177883 +101929727 LOC101929727 - +101929730 LINC01352 HGNC:HGNC:50578|Ensembl:ENSG00000238078 +101929732 LOC101929732 - +101929733 LINC01954 HGNC:HGNC:52779|Ensembl:ENSG00000271952 +101929736 LINC01372 HGNC:HGNC:50623|Ensembl:ENSG00000235475 +101929741 LOC101929741 Ensembl:ENSG00000281731 +101929743 LINC01586 HGNC:HGNC:51434|Ensembl:ENSG00000249487 +101929745 LINC02119 HGNC:HGNC:52975|Ensembl:ENSG00000248461 +101929746 ZNF341-AS1 HGNC:HGNC:50736|Ensembl:ENSG00000230753 +101929747 LOC101929747 - +101929748 LOC101929748 - +101929749 LOC101929749 - +101929750 LOC101929750 - +101929752 LOC101929752 - +101929753 LOC101929753 - +101929754 ZBTB20-AS5 HGNC:HGNC:52841|Ensembl:ENSG00000242290 +101929756 LOC101929756 - +101929759 LOC101929759 Ensembl:ENSG00000246528 +101929760 PIK3IP1-AS1 HGNC:HGNC:41072|Ensembl:ENSG00000228839 +101929762 LOC101929762 - +101929765 LINC01585 HGNC:HGNC:51432|Ensembl:ENSG00000245479 +101929767 LOC101929767 - +101929768 OSMR-AS1 HGNC:HGNC:50296 +101929769 LINC01063 HGNC:HGNC:49092|Ensembl:ENSG00000232065 +101929770 LOC101929770 - +101929771 LINC01655 HGNC:HGNC:52443|Ensembl:ENSG00000227925 +101929773 LOC101929773 - +101929774 LOC101929774 - +101929775 LOC101929775 - +101929777 LOC101929777 Ensembl:ENSG00000108379 +101929780 NBPF25P HGNC:HGNC:45046|Ensembl:ENSG00000272150 +101929784 LOC101929784 - +101929788 LOC101929788 - +101929790 LOC101929790 - +101929796 LOC101929796 Ensembl:ENSG00000273136 +101929798 LOC101929798 Ensembl:ENSG00000275585 +101929800 LOC101929800 - +101929801 FAM91A2P HGNC:HGNC:51523 +101929802 LOC101929802 - +101929812 LOC101929812 - +101929814 LOC101929814 - +101929815 LOC101929815 - +101929816 LOC101929816 - +101929817 LOC101929817 - +101929819 LOC101929819 - +101929820 LOC101929820 - +101929823 LOC101929823 - +101929826 LINC01632 HGNC:HGNC:52419 +101929828 LOC101929828 - +101929829 LOC101929829 - +101929830 LOC101929830 - +101929831 LOC101929831 - +101929835 LOC101929835 - +101929839 LOC101929839 - +101929846 LOC101929846 - +101929861 LOC101929861 - +101929862 LOC101929862 - +101929863 LOC101929863 - +101929866 LOC101929866 - +101929870 LOC101929870 - +101929876 LOC101929876 - +101929878 LOC101929878 - +101929881 LOC101929881 - +101929882 LOC101929882 - +101929894 LOC101929894 - +101929895 LOC101929895 - +101929897 LOC101929897 Ensembl:ENSG00000253408 +101929898 LOC101929898 - +101929901 LOC101929901 Ensembl:ENSG00000229901 +101929902 LOC101929902 - +101929908 LOC101929908 - +101929917 LOC101929917 - +101929918 LOC101929918 - +101929922 LOC101929922 - +101929923 LOC101929923 - +101929926 TEX51 HGNC:HGNC:52387|Ensembl:ENSG00000237524|Vega:OTTHUMG00000153376 +101929927 LOC101929927 - +101929932 LOC101929932 - +101929935 LOC101929935 - +101929937 LOC101929937 - +101929943 LOC101929943 - +101929944 LOC101929944 - +101929946 LOC101929946 - +101929947 LOC101929947 - +101929950 LOC101929950 - +101929951 LOC101929951 - +101929955 LOC101929955 - +101929959 LOC101929959 - +101929963 LOC101929963 - +101929964 LOC101929964 - +101929967 LOC101929967 - +101929970 LOC101929970 - +101929974 LOC101929974 - +101929976 LOC101929976 - +101929977 LOC101929977 - +101929983 PRAMEF27 HGNC:HGNC:51234|Ensembl:ENSG00000274764 +101929984 LOC101929984 - +101929988 LOC101929988 Ensembl:ENSG00000259408 +101929989 LOC101929989 Ensembl:ENSG00000283516|Vega:OTTHUMG00000176581 +101929991 LOC101929991 - +101929996 LOC101929996 - +101929998 LOC101929998 - +101930006 LOC101930006 - +101930009 LOC101930009 - +101930010 LOC101930010 - +101930012 LOC101930012 - +101930013 LOC101930013 - +101930023 LINC02391 HGNC:HGNC:53318 +101930026 LOC101930026 - +101930027 LOC101930027 - +101930028 LOC101930028 - +101930041 LOC101930041 - +101930047 LOC101930047 - +101930048 LOC101930048 - +101930053 LOC101930053 - +101930059 LOC101930059 - +101930071 LOC101930071 Ensembl:ENSG00000213904 +101930072 FP248 - +101930073 LOC101930073 - +101930075 LOC101930075 - +101930081 LOC101930081 - +101930085 LOC101930085 Ensembl:ENSG00000271122 +101930090 LOC101930090 - +101930091 LOC101930091 - +101930094 LOC101930094 Ensembl:ENSG00000239930 +101930100 LOC101930100 - +101930105 LOC101930105 - +101930107 LOC101930107 - +101930109 LOC101930109 - +101930111 LOC101930111 - +101930112 LOC101930112 - +101930114 LOC101930114 Ensembl:ENSG00000227591 +101930115 LOC101930115 - +101930116 LOC101930116 - +101930119 LOC101930119 - +101930122 LOC101930122 - +101930123 LOC101930123 - +101930129 LOC101930129 - +101930131 LOC101930131 - +101930137 LOC101930137 - +101930149 LOC101930149 - +101930150 NF1P9 HGNC:HGNC:51736 +101930151 LOC101930151 - +101930161 LOC101930161 - +101930162 LINC02417 HGNC:HGNC:53347 +101930164 LINC02555 HGNC:HGNC:53593 +101930165 LOC101930165 - +101930169 LOC101930169 - +101930171 LOC101930171 - +101930275 LOC101930275 - +101930276 LOC101930276 - +101930294 LINC02317 HGNC:HGNC:53236 +101930307 LOC101930307 - +101930370 LOC101930370 Ensembl:ENSG00000245213 +101930420 LOC101930420 - +101930421 LOC101930421 - +101930434 LOC101930434 - +101930452 LINC02367 HGNC:HGNC:53290|Ensembl:ENSG00000260423 +101930496 LOC101930496 - +101930531 LOC101930531 - +101930552 LOC101930552 - +101930589 LOC101930589 - +101930593 LOC101930593 - +101930665 LOC101930665 - +101930744 SERPINA15P HGNC:HGNC:44397 +101930745 SERPINE4P HGNC:HGNC:44400 +101930746 LINC00945 HGNC:HGNC:48643|Ensembl:ENSG00000232539 +101930747 LINC00380 HGNC:HGNC:42706 +101930748 LINC00367 HGNC:HGNC:42689|Ensembl:ENSG00000233780 +101930749 LINC00397 HGNC:HGNC:42725|Ensembl:ENSG00000223404 +101937451 LINC01030 HGNC:HGNC:49016|Ensembl:ENSG00000253799 +101954204 LINC00644 HGNC:HGNC:44297|Ensembl:ENSG00000259142 +101954264 RNVU1-4 HGNC:HGNC:48312|Ensembl:ENSG00000277610 +101954266 RNVU1-14 HGNC:HGNC:48319|Ensembl:ENSG00000207501 +101954267 RNVU1-15 HGNC:HGNC:48320|Ensembl:ENSG00000207205 +101954268 RNVU1-20 HGNC:HGNC:48325 +101954269 RNVU1-17 HGNC:HGNC:48322|Ensembl:ENSG00000207349 +101954271 RNU6-9 HGNC:HGNC:34269|Ensembl:ENSG00000207507 +101954272 RNVU1-3 HGNC:HGNC:48311|Ensembl:ENSG00000201183 +101954273 RNVU1-1 HGNC:HGNC:10133|Ensembl:ENSG00000207340 +101954275 RNU6-7 HGNC:HGNC:34284|Ensembl:ENSG00000201654 +101954276 RNVU1-6 HGNC:HGNC:48314|Ensembl:ENSG00000201558 +101954277 RNVU1-19 HGNC:HGNC:48324|Ensembl:ENSG00000275538 +101954278 RNU6-8 HGNC:HGNC:34285|Ensembl:ENSG00000202337 +101978719 LINC00970 HGNC:HGNC:48730|Ensembl:ENSG00000203601 +101978785 PCAT14 HGNC:HGNC:48977 +102030688 LOC102030688 - +102031319 LOC102031319 Ensembl:ENSG00000229327 +102060282 RASSF1-AS1 HGNC:HGNC:49091|Ensembl:ENSG00000281358 +102060414 C2-AS1 HGNC:HGNC:49464|Ensembl:ENSG00000281756 +102095631 VUR7 MIM:615390 +102157400 LINC00384 HGNC:HGNC:42711|Ensembl:ENSG00000232117 +102157401 PCBP2-OT1 HGNC:HGNC:49150|Ensembl:ENSG00000282977 +102157402 AK6 HGNC:HGNC:49151|Ensembl:ENSG00000085231|Vega:OTTHUMG00000187252 +102191832 FBXW7-AS1 HGNC:HGNC:52397|Ensembl:ENSG00000270751 +102216266 DEL3Q13.31 MIM:615433 +102216268 CISTR HGNC:HGNC:49426|Ensembl:ENSG00000260492 +102216341 LINC01109 HGNC:HGNC:49235 +102216342 LINC01108 HGNC:HGNC:49234|Ensembl:ENSG00000226673 +102238594 SPACA6P-AS HGNC:HGNC:49383|Ensembl:ENSG00000269959 +102288414 C11orf98 HGNC:HGNC:51238|Ensembl:ENSG00000278615|Vega:OTTHUMG00000167588 +102388891 MCRIP2P1 HGNC:HGNC:49629 +102443352 LOC102443352 - +102464817 MIR5787 HGNC:HGNC:49930|Ensembl:ENSG00000275334|miRBase:MI0019797 +102464823 MIR6068 HGNC:HGNC:50261|Ensembl:ENSG00000275836|miRBase:MI0020345 +102464824 MIR6069 HGNC:HGNC:50124|Ensembl:ENSG00000274280|miRBase:MI0020346 +102464825 MIR6070 HGNC:HGNC:49950|Ensembl:ENSG00000278433|miRBase:MI0020347 +102464826 MIR6073 HGNC:HGNC:50128|Ensembl:ENSG00000284094|miRBase:MI0020350 +102464827 MIR6074 HGNC:HGNC:50060|Ensembl:ENSG00000276878|miRBase:MI0020351 +102464828 MIR6076 HGNC:HGNC:50232|Ensembl:ENSG00000278038|miRBase:MI0020353 +102464829 MIR6078 HGNC:HGNC:50136|Ensembl:ENSG00000274809|miRBase:MI0020355 +102464830 MIR6079 HGNC:HGNC:50114|Ensembl:ENSG00000283477|miRBase:MI0020356 +102464831 MIR6080 HGNC:HGNC:50142|Ensembl:ENSG00000278581|miRBase:MI0020357 +102464832 MIR6083 HGNC:HGNC:50076|Ensembl:ENSG00000276656|miRBase:MI0020360 +102464833 MIR6084 HGNC:HGNC:50235|Ensembl:ENSG00000284005|miRBase:MI0020361 +102464834 MIR6085 HGNC:HGNC:50002|Ensembl:ENSG00000275451|miRBase:MI0020362 +102464835 MIR6087 HGNC:HGNC:50045|Ensembl:ENSG00000275110|miRBase:MI0020364 +102464836 MIR6088 HGNC:HGNC:50164|Ensembl:ENSG00000275726|miRBase:MI0020365 +102464837 MIR6089 HGNC:HGNC:50179|Ensembl:ENSG00000277120|miRBase:MI0020366 +102465133 MIR6125 HGNC:HGNC:49931|Ensembl:ENSG00000284360|miRBase:MI0021259 +102465134 MIR6126 HGNC:HGNC:50099|Ensembl:ENSG00000273776|miRBase:MI0021260 +102465135 MIR6128 HGNC:HGNC:50109|Ensembl:ENSG00000274770|miRBase:MI0021272 +102465136 MIR378J HGNC:HGNC:49979|Ensembl:ENSG00000274620|miRBase:MI0021273 +102465137 MIR6129 HGNC:HGNC:50220|Ensembl:ENSG00000273500|miRBase:MI0021274 +102465138 MIR6131 HGNC:HGNC:49929|Ensembl:ENSG00000277073|miRBase:MI0021276 +102465139 MIR6133 HGNC:HGNC:50007|Ensembl:ENSG00000276137|miRBase:MI0021278 +102465140 MIR6134 HGNC:HGNC:49951|Ensembl:ENSG00000277569|miRBase:MI0021279 +102465141 MIR6165 HGNC:HGNC:50197|Ensembl:ENSG00000277478|miRBase:MI0021472 +102465246 MIR6499 HGNC:HGNC:49962|Ensembl:ENSG00000276622|miRBase:MI0022209 +102465247 MIR548AY HGNC:HGNC:49943|Ensembl:ENSG00000276147|miRBase:MI0022210 +102465248 MIR6501 HGNC:HGNC:50033|Ensembl:ENSG00000284448|miRBase:MI0022213 +102465249 MIR6502 HGNC:HGNC:50062|Ensembl:ENSG00000284011|miRBase:MI0022214 +102465250 MIR6503 HGNC:HGNC:49968|Ensembl:ENSG00000275344|miRBase:MI0022215 +102465251 MIR6504 HGNC:HGNC:49976|Ensembl:ENSG00000275109|miRBase:MI0022216 +102465252 MIR6506 HGNC:HGNC:50158|Ensembl:ENSG00000284184|miRBase:MI0022218 +102465253 MIR6507 HGNC:HGNC:50199|Ensembl:ENSG00000274056|miRBase:MI0022219 +102465254 MIR6509 HGNC:HGNC:50207|Ensembl:ENSG00000277138|miRBase:MI0022221 +102465255 MIR6512 HGNC:HGNC:50259|Ensembl:ENSG00000278418|miRBase:MI0022224 +102465256 MIR6513 HGNC:HGNC:50247|Ensembl:ENSG00000284173|miRBase:MI0022225 +102465257 MIR6514 HGNC:HGNC:50147|Ensembl:ENSG00000274066|miRBase:MI0022226 +102465427 MIR6715B HGNC:HGNC:50249|Ensembl:ENSG00000283688|miRBase:MI0022549 +102465428 MIR6717 HGNC:HGNC:50000|Ensembl:ENSG00000284122|miRBase:MI0022551 +102465429 MIR6511B1 HGNC:HGNC:50228|Ensembl:ENSG00000284008|miRBase:MI0022552 +102465430 MIR6718 HGNC:HGNC:50195|Ensembl:ENSG00000275518|miRBase:MI0022553 +102465431 MIR6722 HGNC:HGNC:49927|Ensembl:ENSG00000278756|miRBase:MI0022557 +102465432 MIR6723 HGNC:HGNC:50152|Ensembl:ENSG00000278791|miRBase:MI0022558 +102465433 MIR6724-1 HGNC:HGNC:50837|Ensembl:ENSG00000275950|miRBase:MI0022559 +102465434 MIR6726 HGNC:HGNC:50009|Ensembl:ENSG00000278073|miRBase:MI0022571 +102465435 MIR6727 HGNC:HGNC:50171|Ensembl:ENSG00000283712|miRBase:MI0022572 +102465436 MIR6728 HGNC:HGNC:49961|Ensembl:ENSG00000274258|miRBase:MI0022573 +102465437 MIR6731 HGNC:HGNC:50036|Ensembl:ENSG00000278034|miRBase:MI0022576 +102465438 MIR6732 HGNC:HGNC:50066|Ensembl:ENSG00000283724|miRBase:MI0022577 +102465439 MIR6733 HGNC:HGNC:50239|Ensembl:ENSG00000284410|miRBase:MI0022578 +102465440 MIR6735 HGNC:HGNC:50126|Ensembl:ENSG00000274975|miRBase:MI0022580 +102465441 MIR6737 HGNC:HGNC:50273|Ensembl:ENSG00000276584|miRBase:MI0022582 +102465442 MIR6738 HGNC:HGNC:49939|Ensembl:ENSG00000277817|miRBase:MI0022583 +102465443 MIR6740 HGNC:HGNC:50082|Ensembl:ENSG00000275207|miRBase:MI0022585 +102465444 MIR6742 HGNC:HGNC:50090|Ensembl:ENSG00000284311|miRBase:MI0022587 +102465445 MIR6743 HGNC:HGNC:50008|Ensembl:ENSG00000283920|miRBase:MI0022588 +102465446 MIR6746 HGNC:HGNC:49925|Ensembl:ENSG00000277892|miRBase:MI0022591 +102465447 MIR6747 HGNC:HGNC:50027|Ensembl:ENSG00000276102|miRBase:MI0022592 +102465448 MIR6748 HGNC:HGNC:50141|Ensembl:ENSG00000284535|miRBase:MI0022593 +102465449 MIR6751 HGNC:HGNC:49983|Ensembl:ENSG00000284489|miRBase:MI0022596 +102465450 MIR6752 HGNC:HGNC:50020|Ensembl:ENSG00000276769|miRBase:MI0022597 +102465451 MIR6753 HGNC:HGNC:50255|Ensembl:ENSG00000275022|miRBase:MI0022598 +102465452 MIR6755 HGNC:HGNC:50224|Ensembl:ENSG00000283744|miRBase:MI0022600 +102465453 MIR6756 HGNC:HGNC:49974|Ensembl:ENSG00000284148|miRBase:MI0022601 +102465454 MIR6758 HGNC:HGNC:50038|Ensembl:ENSG00000284152|miRBase:MI0022603 +102465455 MIR6760 HGNC:HGNC:49955|Ensembl:ENSG00000273700|miRBase:MI0022605 +102465456 MIR6761 HGNC:HGNC:49949|Ensembl:ENSG00000274697|miRBase:MI0022606 +102465457 MIR6762 HGNC:HGNC:50168|Ensembl:ENSG00000274822|miRBase:MI0022607 +102465458 MIR6765 HGNC:HGNC:50030|Ensembl:ENSG00000273778|miRBase:MI0022610 +102465459 MIR6767 HGNC:HGNC:50133|Ensembl:ENSG00000283180|miRBase:MI0022612 +102465460 MIR6768 HGNC:HGNC:50264|Ensembl:ENSG00000274805|miRBase:MI0022613 +102465461 MIR6770-1 HGNC:HGNC:50223|Ensembl:ENSG00000278265|miRBase:MI0022615 +102465462 MIR6771 HGNC:HGNC:50212|Ensembl:ENSG00000274969|miRBase:MI0022616 +102465463 MIR6772 HGNC:HGNC:50064|Ensembl:ENSG00000274816|miRBase:MI0022617 +102465464 MIR6775 HGNC:HGNC:50100|Ensembl:ENSG00000278598|miRBase:MI0022620 +102465465 MIR6776 HGNC:HGNC:50193|Ensembl:ENSG00000273606|miRBase:MI0022621 +102465466 MIR6777 HGNC:HGNC:50173|Ensembl:ENSG00000274111|miRBase:MI0022622 +102465467 MIR6779 HGNC:HGNC:50148|Ensembl:ENSG00000277057|miRBase:MI0022624 +102465468 MIR6781 HGNC:HGNC:50185|Ensembl:ENSG00000278447|miRBase:MI0022626 +102465469 MIR6782 HGNC:HGNC:50270|Ensembl:ENSG00000275107|miRBase:MI0022627 +102465470 MIR6784 HGNC:HGNC:49988|Ensembl:ENSG00000277249|miRBase:MI0022629 +102465471 MIR6786 HGNC:HGNC:49970|Ensembl:ENSG00000277784|miRBase:MI0022631 +102465472 MIR6787 HGNC:HGNC:50209|Ensembl:ENSG00000284574|miRBase:MI0022632 +102465473 MIR6790 HGNC:HGNC:50161|Ensembl:ENSG00000273758|miRBase:MI0022635 +102465474 MIR6791 HGNC:HGNC:50097|Ensembl:ENSG00000283950|miRBase:MI0022636 +102465475 MIR6792 HGNC:HGNC:50054|Ensembl:ENSG00000273657|miRBase:MI0022637 +102465476 MIR6795 HGNC:HGNC:50031|Ensembl:ENSG00000275711|miRBase:MI0022640 +102465477 MIR6796 HGNC:HGNC:50186|Ensembl:ENSG00000275652|miRBase:MI0022641 +102465478 MIR6797 HGNC:HGNC:50169|Ensembl:ENSG00000276926|miRBase:MI0022642 +102465479 MIR6799 HGNC:HGNC:50162|Ensembl:ENSG00000276270|miRBase:MI0022644 +102465480 MIR6800 HGNC:HGNC:50042|Ensembl:ENSG00000284114|miRBase:MI0022645 +102465481 MIR6802 HGNC:HGNC:50154|Ensembl:ENSG00000278328|miRBase:MI0022647 +102465482 MIR6804 HGNC:HGNC:50253|Ensembl:ENSG00000275519|miRBase:MI0022649 +102465483 MIR6805 HGNC:HGNC:50215|Ensembl:ENSG00000284029|miRBase:MI0022650 +102465484 MIR6806 HGNC:HGNC:49937|Ensembl:ENSG00000277588|miRBase:MI0022651 +102465485 MIR6809 HGNC:HGNC:49926|Ensembl:ENSG00000275458|miRBase:MI0022654 +102465486 MIR6811 HGNC:HGNC:49944|Ensembl:ENSG00000277842|miRBase:MI0022656 +102465487 MIR6812 HGNC:HGNC:50116|Ensembl:ENSG00000273555|miRBase:MI0022657 +102465488 MIR6814 HGNC:HGNC:50145|Ensembl:ENSG00000275166|miRBase:MI0022659 +102465489 MIR6815 HGNC:HGNC:50225|Ensembl:ENSG00000275167|miRBase:MI0022660 +102465490 MIR6816 HGNC:HGNC:50256|Ensembl:ENSG00000278278|miRBase:MI0022661 +102465491 MIR6819 HGNC:HGNC:50155|Ensembl:ENSG00000278420|miRBase:MI0022664 +102465492 MIR6820 HGNC:HGNC:50095|Ensembl:ENSG00000284289|miRBase:MI0022665 +102465493 MIR6821 HGNC:HGNC:49980|Ensembl:ENSG00000276753|miRBase:MI0022666 +102465494 MIR6823 HGNC:HGNC:49952|Ensembl:ENSG00000278799|miRBase:MI0022668 +102465495 MIR6824 HGNC:HGNC:49946|Ensembl:ENSG00000284364|miRBase:MI0022669 +102465496 MIR6826 HGNC:HGNC:50001|Ensembl:ENSG00000278658|miRBase:MI0022671 +102465497 MIR6828 HGNC:HGNC:50057|Ensembl:ENSG00000283474|miRBase:MI0022673 +102465498 MIR6830 HGNC:HGNC:49966|Ensembl:ENSG00000283678|miRBase:MI0022675 +102465499 MIR6831 HGNC:HGNC:49936|Ensembl:ENSG00000283717|miRBase:MI0022676 +102465500 MIR6833 HGNC:HGNC:50245|Ensembl:ENSG00000277264|miRBase:MI0022678 +102465501 MIR6834 HGNC:HGNC:50108|Ensembl:ENSG00000284064|miRBase:MI0022679 +102465502 MIR6835 HGNC:HGNC:49963|Ensembl:ENSG00000276404|miRBase:MI0022680 +102465503 MIR6836 HGNC:HGNC:50067|Ensembl:ENSG00000284047|miRBase:MI0022682 +102465504 MIR6838 HGNC:HGNC:50050|Ensembl:ENSG00000283969|miRBase:MI0022684 +102465505 MIR6839 HGNC:HGNC:49953|Ensembl:ENSG00000275667|miRBase:MI0022685 +102465506 MIR6841 HGNC:HGNC:50070|Ensembl:ENSG00000283327|miRBase:MI0022687 +102465507 MIR6842 HGNC:HGNC:50254|Ensembl:ENSG00000273836|miRBase:MI0022688 +102465508 MIR6843 HGNC:HGNC:50240|Ensembl:ENSG00000284280|miRBase:MI0022689 +102465509 MIR6846 HGNC:HGNC:50026|Ensembl:ENSG00000277888|miRBase:MI0022692 +102465510 MIR6847 HGNC:HGNC:50022|Ensembl:ENSG00000284200|miRBase:MI0022693 +102465511 MIR6848 HGNC:HGNC:50176|Ensembl:ENSG00000284229|miRBase:MI0022694 +102465512 MIR6851 HGNC:HGNC:50083|Ensembl:ENSG00000275651|miRBase:MI0022697 +102465513 MIR6852 HGNC:HGNC:49993|Ensembl:ENSG00000284195|miRBase:MI0022698 +102465514 MIR6854 HGNC:HGNC:50084|Ensembl:ENSG00000278412|miRBase:MI0022700 +102465515 MIR6856 HGNC:HGNC:50242|Ensembl:ENSG00000277713|miRBase:MI0022702 +102465516 MIR6857 HGNC:HGNC:50263|Ensembl:ENSG00000278204|miRBase:MI0022703 +102465517 MIR6858 HGNC:HGNC:50250|Ensembl:ENSG00000276350|miRBase:MI0022704 +102465518 MIR6860 HGNC:HGNC:50086|Ensembl:ENSG00000283326|miRBase:MI0022707 +102465519 MIR6861 HGNC:HGNC:50129|Ensembl:ENSG00000283793|miRBase:MI0022708 +102465520 MIR6862-1 HGNC:HGNC:50052|Ensembl:ENSG00000275429|miRBase:MI0022709 +102465521 MIR6864 HGNC:HGNC:50226|Ensembl:ENSG00000274300|miRBase:MI0022711 +102465522 MIR6865 HGNC:HGNC:50182|Ensembl:ENSG00000278517|miRBase:MI0022712 +102465523 MIR6867 HGNC:HGNC:50134|Ensembl:ENSG00000274621|miRBase:MI0022714 +102465524 MIR6869 HGNC:HGNC:50056|Ensembl:ENSG00000284436|miRBase:MI0022716 +102465525 MIR6870 HGNC:HGNC:50184|Ensembl:ENSG00000273745|miRBase:MI0022717 +102465526 MIR6872 HGNC:HGNC:50037|Ensembl:ENSG00000283848|miRBase:MI0022719 +102465527 MIR6876 HGNC:HGNC:50181|Ensembl:ENSG00000274988|miRBase:MI0022723 +102465528 MIR6877 HGNC:HGNC:50205|Ensembl:ENSG00000273932|miRBase:MI0022724 +102465529 MIR6878 HGNC:HGNC:50269|Ensembl:ENSG00000283933|miRBase:MI0022725 +102465530 MIR6881 HGNC:HGNC:50098|Ensembl:ENSG00000277391|miRBase:MI0022728 +102465531 MIR6882 HGNC:HGNC:49928|Ensembl:ENSG00000275411|miRBase:MI0022729 +102465532 MIR6883 HGNC:HGNC:50019|Ensembl:ENSG00000284117|miRBase:MI0022730 +102465533 MIR6885 HGNC:HGNC:50221|Ensembl:ENSG00000274390|miRBase:MI0022732 +102465534 MIR6886 HGNC:HGNC:50121|Ensembl:ENSG00000284553|miRBase:MI0022733 +102465535 MIR6888 HGNC:HGNC:50071|Ensembl:ENSG00000275141|miRBase:MI0022735 +102465536 MIR6890 HGNC:HGNC:49990|Ensembl:ENSG00000284488|miRBase:MI0022737 +102465537 MIR6891 HGNC:HGNC:50243|Ensembl:ENSG00000277402|miRBase:MI0022738 +102465538 MIR6892 HGNC:HGNC:50053|Ensembl:ENSG00000278449|miRBase:MI0022739 +102465539 MIR6895 HGNC:HGNC:50210|Ensembl:ENSG00000276575|miRBase:MI0022742 +102465665 MIR7107 HGNC:HGNC:50006|Ensembl:ENSG00000284402|miRBase:MI0022958 +102465666 MIR7109 HGNC:HGNC:50122|Ensembl:ENSG00000284082|miRBase:MI0022960 +102465667 MIR7110 HGNC:HGNC:50024|Ensembl:ENSG00000284421|miRBase:MI0022961 +102465668 MIR7111 HGNC:HGNC:50073|Ensembl:ENSG00000276712|miRBase:MI0022962 +102465669 MIR7113 HGNC:HGNC:49947|Ensembl:ENSG00000284293|miRBase:MI0022964 +102465683 MIR6511A3 HGNC:HGNC:50265|Ensembl:ENSG00000276311|miRBase:MI0023565 +102465684 MIR6511A4 HGNC:HGNC:50188|Ensembl:ENSG00000273613|miRBase:MI0023566 +102465688 MIR7150 HGNC:HGNC:49982|Ensembl:ENSG00000274932|miRBase:MI0023610 +102465689 MIR7152 HGNC:HGNC:50257|Ensembl:ENSG00000274824|miRBase:MI0023612 +102465690 MIR7153 HGNC:HGNC:50190|Ensembl:ENSG00000283492|miRBase:MI0023613 +102465691 MIR7154 HGNC:HGNC:49972|Ensembl:ENSG00000276639|miRBase:MI0023614 +102465692 MIR7157 HGNC:HGNC:50010|Ensembl:ENSG00000283506|miRBase:MI0023617 +102465693 MIR7158 HGNC:HGNC:49971|Ensembl:ENSG00000276733|miRBase:MI0023618 +102465694 MIR7161 HGNC:HGNC:49985|Ensembl:ENSG00000278571|miRBase:MI0023619 +102465695 MIR7160 HGNC:HGNC:50028|Ensembl:ENSG00000273593|miRBase:MI0023621 +102465696 MIR486-2 HGNC:HGNC:50213|Ensembl:ENSG00000283450|miRBase:MI0023622 +102465752 MIR7641-1 HGNC:HGNC:49995|Ensembl:ENSG00000280773|miRBase:MI0024975 +102465753 MIR7641-2 HGNC:HGNC:50214|Ensembl:ENSG00000280494|miRBase:MI0024976 +102465800 MIR7702 HGNC:HGNC:50216|Ensembl:ENSG00000274263|miRBase:MI0025238 +102465801 MIR7703 HGNC:HGNC:50271|Ensembl:ENSG00000283856|miRBase:MI0025239 +102465802 MIR7704 HGNC:HGNC:50089|Ensembl:ENSG00000283880|miRBase:MI0025240 +102465803 MIR7706 HGNC:HGNC:50110|Ensembl:ENSG00000284160|miRBase:MI0025242 +102465832 MIR7843 HGNC:HGNC:50074|Ensembl:ENSG00000273830|miRBase:MI0025510 +102465833 MIR4433B HGNC:HGNC:50258|Ensembl:ENSG00000264297|miRBase:MI0025511 +102465834 MIR7844 HGNC:HGNC:50044|Ensembl:ENSG00000283818|miRBase:MI0025514 +102465835 MIR7845 HGNC:HGNC:50267|Ensembl:ENSG00000277590|miRBase:MI0025515 +102465836 MIR7846 HGNC:HGNC:50029|Ensembl:ENSG00000283789|miRBase:MI0025516 +102465837 MIR7849 HGNC:HGNC:50166|Ensembl:ENSG00000278438|miRBase:MI0025519 +102465838 MIR7850 HGNC:HGNC:50118|Ensembl:ENSG00000277904|miRBase:MI0025520 +102465839 MIR7852 HGNC:HGNC:50201|Ensembl:ENSG00000275455|miRBase:MI0025522 +102465840 MIR7854 HGNC:HGNC:50047|Ensembl:ENSG00000277255|miRBase:MI0025524 +102465841 MIR7855 HGNC:HGNC:50244|Ensembl:ENSG00000284269|miRBase:MI0025525 +102465842 MIR7856 HGNC:HGNC:50268|Ensembl:ENSG00000278281|miRBase:MI0025526 +102465854 MIR548BA HGNC:HGNC:50260|Ensembl:ENSG00000212036|miRBase:MI0025747 +102465855 MIR7973-2 HGNC:HGNC:50080|Ensembl:ENSG00000283614|miRBase:MI0025749 +102465856 MIR7974 HGNC:HGNC:49992|Ensembl:ENSG00000274713|miRBase:MI0025750 +102465857 MIR7976 HGNC:HGNC:50092|Ensembl:ENSG00000276083|miRBase:MI0025752 +102465858 MIR7977 HGNC:HGNC:49969|Ensembl:ENSG00000283333|miRBase:MI0025753 +102465859 MIR7978 HGNC:HGNC:50113|Ensembl:ENSG00000283281|miRBase:MI0025754 +102465860 MIR8054 HGNC:HGNC:50177|Ensembl:ENSG00000275868|miRBase:MI0025890 +102465861 MIR8055 HGNC:HGNC:50241|Ensembl:ENSG00000276580|miRBase:MI0025891 +102465862 MIR8056 HGNC:HGNC:49948|Ensembl:ENSG00000274994|miRBase:MI0025892 +102465863 MIR8058 HGNC:HGNC:50018|Ensembl:ENSG00000277387|miRBase:MI0025894 +102465864 MIR8060 HGNC:HGNC:50180|Ensembl:ENSG00000278103|miRBase:MI0025896 +102465865 MIR8062 HGNC:HGNC:49975|Ensembl:ENSG00000278159|miRBase:MI0025898 +102465866 MIR8064 HGNC:HGNC:50236|Ensembl:ENSG00000275789|miRBase:MI0025900 +102465867 MIR8065 HGNC:HGNC:49959|Ensembl:ENSG00000273648|miRBase:MI0025901 +102465868 MIR8066 HGNC:HGNC:50043|Ensembl:ENSG00000273882|miRBase:MI0025902 +102465869 MIR8067 HGNC:HGNC:49934|Ensembl:ENSG00000277919|miRBase:MI0025903 +102465870 MIR8070 HGNC:HGNC:50274|Ensembl:ENSG00000278529|miRBase:MI0025906 +102465871 MIR8071-1 HGNC:HGNC:50041|Ensembl:ENSG00000274172|miRBase:MI0025907 +102465872 MIR8073 HGNC:HGNC:50131|Ensembl:ENSG00000276765|miRBase:MI0025909 +102465873 MIR8074 HGNC:HGNC:50105|Ensembl:ENSG00000278617|miRBase:MI0025910 +102465874 MIR8075 HGNC:HGNC:50172|Ensembl:ENSG00000277942|miRBase:MI0025911 +102465875 MIR8077 HGNC:HGNC:50266|Ensembl:ENSG00000277533|miRBase:MI0025913 +102465876 MIR8079 HGNC:HGNC:50021|Ensembl:ENSG00000276319|miRBase:MI0025915 +102465877 MIR8080 HGNC:HGNC:49989|Ensembl:ENSG00000276917|miRBase:MI0025916 +102465878 MIR8082 HGNC:HGNC:50111|Ensembl:ENSG00000275810|miRBase:MI0025918 +102465879 MIR8085 HGNC:HGNC:50120|Ensembl:ENSG00000284258|miRBase:MI0025921 +102465880 MIR8086 HGNC:HGNC:50107|Ensembl:ENSG00000275036|miRBase:MI0025922 +102465881 MIR8087 HGNC:HGNC:50059|Ensembl:ENSG00000278483|miRBase:MI0025923 +102465882 MIR8089 HGNC:HGNC:50196|Ensembl:ENSG00000277912|miRBase:MI0025925 +102465906 MIR7112 HGNC:HGNC:50149|Ensembl:ENSG00000284054|miRBase:MI0022963 +102465907 MIR6862-2 HGNC:HGNC:50192|Ensembl:ENSG00000278340|miRBase:MI0026415 +102465908 MIR6770-2 HGNC:HGNC:50115|Ensembl:ENSG00000277698|miRBase:MI0026418 +102465909 MIR6859-2 HGNC:HGNC:49954|Ensembl:ENSG00000273874|miRBase:MI0026420 +102465910 MIR6859-3 HGNC:HGNC:50248|Ensembl:ENSG00000275449|miRBase:MI0026421 +102465944 MIR6072 HGNC:HGNC:50144|Ensembl:ENSG00000278069|miRBase:MI0020349 +102465974 MIR6719 HGNC:HGNC:50012|Ensembl:ENSG00000277759|miRBase:MI0022554 +102465975 MIR6763 HGNC:HGNC:50139|Ensembl:ENSG00000277052|miRBase:MI0022608 +102465976 MIR6807 HGNC:HGNC:50191|Ensembl:ENSG00000275924|miRBase:MI0022652 +102465977 MIR6829 HGNC:HGNC:50055|Ensembl:ENSG00000276489|miRBase:MI0022674 +102465978 MIR6850 HGNC:HGNC:50093|Ensembl:ENSG00000283764|miRBase:MI0022696 +102465985 MIR6511B2 HGNC:HGNC:50230|Ensembl:ENSG00000283346|miRBase:MI0023431 +102465993 MIR7847 HGNC:HGNC:50153|Ensembl:ENSG00000284594|miRBase:MI0025517 +102465995 MIR8081 HGNC:HGNC:50123|Ensembl:ENSG00000277889|miRBase:MI0025917 +102466081 MIR5739 HGNC:HGNC:49977|Ensembl:ENSG00000276162|miRBase:MI0019412 +102466103 MIR6075 HGNC:HGNC:50198|Ensembl:ENSG00000273742|miRBase:MI0020352 +102466104 MIR6090 HGNC:HGNC:50204|Ensembl:ENSG00000276176|miRBase:MI0020367 +102466162 MIR548AZ HGNC:HGNC:49981|Ensembl:ENSG00000276479|miRBase:MI0022212 +102466189 MIR6715A HGNC:HGNC:49996|Ensembl:ENSG00000276857|miRBase:MI0022548 +102466190 MIR6721 HGNC:HGNC:50049|Ensembl:ENSG00000284469|miRBase:MI0022556 +102466191 MIR6736 HGNC:HGNC:50072|Ensembl:ENSG00000278549|miRBase:MI0022581 +102466192 MIR6750 HGNC:HGNC:49965|Ensembl:ENSG00000274986|miRBase:MI0022595 +102466193 MIR6757 HGNC:HGNC:50160|Ensembl:ENSG00000278108|miRBase:MI0022602 +102466194 MIR6773 HGNC:HGNC:50132|Ensembl:ENSG00000284259|miRBase:MI0022618 +102466195 MIR6780A HGNC:HGNC:50069|Ensembl:ENSG00000275273|miRBase:MI0022625 +102466196 MIR6794 HGNC:HGNC:50117|Ensembl:ENSG00000276181|miRBase:MI0022639 +102466197 MIR6810 HGNC:HGNC:49987|Ensembl:ENSG00000278524|miRBase:MI0022655 +102466198 MIR6817 HGNC:HGNC:50112|Ensembl:ENSG00000277872|miRBase:MI0022662 +102466199 MIR6825 HGNC:HGNC:50208|Ensembl:ENSG00000275067|miRBase:MI0022670 +102466200 MIR6844 HGNC:HGNC:50135|Ensembl:ENSG00000284087|miRBase:MI0022690 +102466201 MIR6853 HGNC:HGNC:49945|Ensembl:ENSG00000273945|miRBase:MI0022699 +102466202 MIR6769B HGNC:HGNC:50016|Ensembl:ENSG00000278465|miRBase:MI0022706 +102466203 MIR6874 HGNC:HGNC:50146|Ensembl:ENSG00000283419|miRBase:MI0022721 +102466204 MIR6880 HGNC:HGNC:50187|Ensembl:ENSG00000275967|miRBase:MI0022727 +102466205 MIR6887 HGNC:HGNC:50065|Ensembl:ENSG00000284065|miRBase:MI0022734 +102466222 MIR7106 HGNC:HGNC:50085|Ensembl:ENSG00000276908|miRBase:MI0022957 +102466223 MIR7114 HGNC:HGNC:50157|Ensembl:ENSG00000284317|miRBase:MI0022965 +102466225 MIR6077 HGNC:HGNC:50025|Ensembl:ENSG00000278596|miRBase:MI0020354 +102466227 MIR7162 HGNC:HGNC:50189|Ensembl:ENSG00000284277|miRBase:MI0023623 +102466235 MIR7515 HGNC:HGNC:49839|Ensembl:ENSG00000283394|miRBase:MI0024354 +102466247 MIR1273H HGNC:HGNC:49973|Ensembl:ENSG00000274466|miRBase:MI0025512 +102466250 MIR7973-1 HGNC:HGNC:50040|Ensembl:ENSG00000278098|miRBase:MI0025748 +102466251 MIR8061 HGNC:HGNC:50077|Ensembl:ENSG00000277636|miRBase:MI0025897 +102466252 MIR8069-1 HGNC:HGNC:50262|Ensembl:ENSG00000284550|miRBase:MI0025905 +102466253 MIR8076 HGNC:HGNC:49997|Ensembl:ENSG00000275670|miRBase:MI0025912 +102466259 MIR6770-3 HGNC:HGNC:50034|Ensembl:ENSG00000275391|miRBase:MI0026419 +102466268 MIR6511A1 HGNC:HGNC:50119|Ensembl:ENSG00000275259|miRBase:MI0022223 +102466270 MIR6741 HGNC:HGNC:50004|Ensembl:ENSG00000284519|miRBase:MI0022586 +102466271 MIR6893 HGNC:HGNC:50130|Ensembl:ENSG00000276598|miRBase:MI0022740 +102466515 MIR1199 HGNC:HGNC:50081|Ensembl:ENSG00000284081|miRBase:MI0020340 +102466516 MIR6071 HGNC:HGNC:50229|Ensembl:ENSG00000278783|miRBase:MI0020348 +102466518 MIR6081 HGNC:HGNC:50151|Ensembl:ENSG00000274115|miRBase:MI0020358 +102466519 MIR6086 HGNC:HGNC:49986|Ensembl:ENSG00000283493|miRBase:MI0020363 +102466615 MIR6127 HGNC:HGNC:50163|Ensembl:ENSG00000276835|miRBase:MI0021271 +102466616 MIR6132 HGNC:HGNC:50272|Ensembl:ENSG00000283923|miRBase:MI0021277 +102466656 MIR6500 HGNC:HGNC:49935|Ensembl:ENSG00000275816|miRBase:MI0022211 +102466657 MIR6505 HGNC:HGNC:50104|Ensembl:ENSG00000275770|miRBase:MI0022217 +102466658 MIR6510 HGNC:HGNC:50101|Ensembl:ENSG00000283796|miRBase:MI0022222 +102466659 MIR6515 HGNC:HGNC:50227|Ensembl:ENSG00000274417|miRBase:MI0022227 +102466719 MIR6716 HGNC:HGNC:50048|Ensembl:ENSG00000284246|miRBase:MI0022550 +102466720 MIR6720 HGNC:HGNC:50032|Ensembl:ENSG00000275859|miRBase:MI0022555 +102466721 MIR892C HGNC:HGNC:50194|Ensembl:ENSG00000252219|miRBase:MI0022560 +102466722 MIR6730 HGNC:HGNC:50222|Ensembl:ENSG00000276830|miRBase:MI0022575 +102466723 MIR6734 HGNC:HGNC:50219|Ensembl:ENSG00000283836|miRBase:MI0022579 +102466724 MIR6739 HGNC:HGNC:50165|Ensembl:ENSG00000277681|miRBase:MI0022584 +102466725 MIR6744 HGNC:HGNC:50051|Ensembl:ENSG00000275669|miRBase:MI0022589 +102466726 MIR6745 HGNC:HGNC:50106|Ensembl:ENSG00000275208|miRBase:MI0022590 +102466727 MIR6749 HGNC:HGNC:50087|Ensembl:ENSG00000274314|miRBase:MI0022594 +102466728 MIR6754 HGNC:HGNC:50203|Ensembl:ENSG00000278349|miRBase:MI0022599 +102466729 MIR6759 HGNC:HGNC:50063|Ensembl:ENSG00000283621|miRBase:MI0022604 +102466730 MIR6764 HGNC:HGNC:49994|Ensembl:ENSG00000283840|miRBase:MI0022609 +102466731 MIR6769A HGNC:HGNC:50079|Ensembl:ENSG00000276641|miRBase:MI0022614 +102466732 MIR6774 HGNC:HGNC:50202|Ensembl:ENSG00000274134|miRBase:MI0022619 +102466733 MIR6778 HGNC:HGNC:50183|Ensembl:ENSG00000283772|miRBase:MI0022623 +102466734 MIR6783 HGNC:HGNC:50159|Ensembl:ENSG00000278223|miRBase:MI0022628 +102466735 MIR6788 HGNC:HGNC:50078|Ensembl:ENSG00000274838|miRBase:MI0022633 +102466736 MIR6789 HGNC:HGNC:50094|Ensembl:ENSG00000284129|miRBase:MI0022634 +102466737 MIR6793 HGNC:HGNC:50251|Ensembl:ENSG00000275640|miRBase:MI0022638 +102466738 MIR6798 HGNC:HGNC:50013|Ensembl:ENSG00000273898|miRBase:MI0022643 +102466739 MIR6803 HGNC:HGNC:50035|Ensembl:ENSG00000278264|miRBase:MI0022648 +102466740 MIR6808 HGNC:HGNC:50046|Ensembl:ENSG00000284372|miRBase:MI0022653 +102466741 MIR6813 HGNC:HGNC:50017|Ensembl:ENSG00000274034|miRBase:MI0022658 +102466742 MIR6818 HGNC:HGNC:49940|Ensembl:ENSG00000275818|miRBase:MI0022663 +102466743 MIR6822 HGNC:HGNC:49999|Ensembl:ENSG00000284158|miRBase:MI0022667 +102466744 MIR6827 HGNC:HGNC:50234|Ensembl:ENSG00000277723|miRBase:MI0022672 +102466745 MIR6832 HGNC:HGNC:50140|Ensembl:ENSG00000274494|miRBase:MI0022677 +102466746 MIR6780B HGNC:HGNC:50237|Ensembl:ENSG00000276770|miRBase:MI0022681 +102466747 MIR6840 HGNC:HGNC:50138|Ensembl:ENSG00000284012|miRBase:MI0022686 +102466748 MIR6845 HGNC:HGNC:49956|Ensembl:ENSG00000284142|miRBase:MI0022691 +102466749 MIR6849 HGNC:HGNC:49991|Ensembl:ENSG00000283770|miRBase:MI0022695 +102466750 MIR6855 HGNC:HGNC:50061|Ensembl:ENSG00000276124|miRBase:MI0022701 +102466751 MIR6859-1 HGNC:HGNC:50039|Ensembl:ENSG00000278267|miRBase:MI0022705 +102466752 MIR6863 HGNC:HGNC:49942|Ensembl:ENSG00000283471|miRBase:MI0022710 +102466753 MIR6868 HGNC:HGNC:50096|Ensembl:ENSG00000275360|miRBase:MI0022715 +102466754 MIR6873 HGNC:HGNC:50231|Ensembl:ENSG00000284517|miRBase:MI0022720 +102466755 MIR6875 HGNC:HGNC:50015|Ensembl:ENSG00000283821|miRBase:MI0022722 +102466756 MIR6879 HGNC:HGNC:49957|Ensembl:ENSG00000278851|miRBase:MI0022726 +102466757 MIR6884 HGNC:HGNC:50091|Ensembl:ENSG00000283721|miRBase:MI0022731 +102466758 MIR6889 HGNC:HGNC:50014|Ensembl:ENSG00000274552|miRBase:MI0022736 +102466759 MIR6894 HGNC:HGNC:49938|Ensembl:ENSG00000277474|miRBase:MI0022741 +102466806 MIR7108 HGNC:HGNC:49998|Ensembl:ENSG00000283728|miRBase:MI0022959 +102466812 MIR6511A2 HGNC:HGNC:50150|Ensembl:ENSG00000278221|miRBase:MI0023564 +102466814 MIR7151 HGNC:HGNC:50170|Ensembl:ENSG00000276866|miRBase:MI0023611 +102466815 MIR7155 HGNC:HGNC:50005|Ensembl:ENSG00000278359|miRBase:MI0023615 +102466816 MIR7159 HGNC:HGNC:49978|Ensembl:ENSG00000276824|miRBase:MI0023620 +102466854 MIR7705 HGNC:HGNC:50143|Ensembl:ENSG00000284570|miRBase:MI0025241 +102466864 MIR6516 HGNC:HGNC:50233|Ensembl:ENSG00000284250|miRBase:MI0025513 +102466865 MIR7848 HGNC:HGNC:50058|Ensembl:ENSG00000276961|miRBase:MI0025518 +102466866 MIR7853 HGNC:HGNC:49933|Ensembl:ENSG00000263572|miRBase:MI0025523 +102466872 MIR7975 HGNC:HGNC:49967|Ensembl:ENSG00000275863|miRBase:MI0025751 +102466873 MIR8052 HGNC:HGNC:50252|Ensembl:ENSG00000274999|miRBase:MI0025888 +102466874 MIR8057 HGNC:HGNC:49960|Ensembl:ENSG00000276221|miRBase:MI0025893 +102466875 MIR8063 HGNC:HGNC:50088|Ensembl:ENSG00000277202|miRBase:MI0025899 +102466876 MIR8068 HGNC:HGNC:50238|Ensembl:ENSG00000273912|miRBase:MI0025904 +102466877 MIR8072 HGNC:HGNC:50174|Ensembl:ENSG00000284425|miRBase:MI0025908 +102466878 MIR8078 HGNC:HGNC:50102|Ensembl:ENSG00000277521|miRBase:MI0025914 +102466879 MIR8083 HGNC:HGNC:50211|Ensembl:ENSG00000274940|miRBase:MI0025919 +102466880 MIR8088 HGNC:HGNC:50167|Ensembl:ENSG00000275335|miRBase:MI0025924 +102466889 MIR8071-2 HGNC:HGNC:49958|Ensembl:ENSG00000277030|miRBase:MI0026417 +102466906 MIR6124 HGNC:HGNC:50200|Ensembl:ENSG00000275373|miRBase:MI0021258 +102466911 MIR6785 HGNC:HGNC:50206|Ensembl:ENSG00000284595|miRBase:MI0022630 +102466912 MIR6871 HGNC:HGNC:49964|Ensembl:ENSG00000276169|miRBase:MI0022718 +102466918 MIR8059 HGNC:HGNC:50068|Ensembl:ENSG00000278672|miRBase:MI0025895 +102466953 MIR6082 HGNC:HGNC:49984|Ensembl:ENSG00000278502|miRBase:MI0020359 +102466967 MIR6130 HGNC:HGNC:50156|Ensembl:ENSG00000275469|miRBase:MI0021275 +102466972 MIR6508 HGNC:HGNC:50217|Ensembl:ENSG00000275523|miRBase:MI0022220 +102466982 MIR6729 HGNC:HGNC:50103|Ensembl:ENSG00000276869|miRBase:MI0022574 +102466983 MIR6766 HGNC:HGNC:49941|Ensembl:ENSG00000275101|miRBase:MI0022611 +102466984 MIR6801 HGNC:HGNC:50178|Ensembl:ENSG00000274380|miRBase:MI0022646 +102466985 MIR6837 HGNC:HGNC:50125|Ensembl:ENSG00000284067|miRBase:MI0022683 +102466986 MIR6866 HGNC:HGNC:49932|Ensembl:ENSG00000284144|miRBase:MI0022713 +102466995 MIR7156 HGNC:HGNC:50023|Ensembl:ENSG00000276081|miRBase:MI0023616 +102467003 MIR7851 HGNC:HGNC:50127|Ensembl:ENSG00000278520|miRBase:MI0025521 +102467004 MIR8053 HGNC:HGNC:50137|Ensembl:ENSG00000277388|miRBase:MI0025889 +102467005 MIR8084 HGNC:HGNC:50075|Ensembl:ENSG00000277063|miRBase:MI0025920 +102467073 HRAT5 - +102467074 LINC01377 HGNC:HGNC:50642|Ensembl:ENSG00000249808 +102467075 LINC01017 HGNC:HGNC:50641|Ensembl:ENSG00000250716 +102467077 LINC00603 HGNC:HGNC:43918 +102467079 LINC02180 HGNC:HGNC:53042|Ensembl:ENSG00000261749 +102467080 LOC102467080 - +102467081 LOC102467081 - +102467146 MAFTRR MIM:616264|HGNC:HGNC:51525|Ensembl:ENSG00000261390 +102467147 LINC01948 HGNC:HGNC:52772|Ensembl:ENSG00000248727 +102467212 LINC02115 HGNC:HGNC:52970|Ensembl:ENSG00000248757 +102467213 LINC01950 HGNC:HGNC:52773|Ensembl:ENSG00000251027 +102467214 LINC02200 HGNC:HGNC:53066 +102467216 LOC102467216 - +102467217 LOC102467217 - +102467222 LOC102467222 Ensembl:ENSG00000253147 +102467223 LINC02214 HGNC:HGNC:53081 +102467224 LINC02147 HGNC:HGNC:53007 +102467225 LINC02215 HGNC:HGNC:53082|Ensembl:ENSG00000249128 +102467226 LOC102467226 - +102467655 LINC02219 HGNC:HGNC:53086|Ensembl:ENSG00000253787 +102477328 LINC02056 HGNC:HGNC:52898|Ensembl:ENSG00000248371 +102503427 LOC102503427 - +102503428 DUP22Q13 MIM:615538 +102503429 LINC01335 HGNC:HGNC:50542|Ensembl:ENSG00000248942 +102524628 RASGRF2-AS1 HGNC:HGNC:40499|Ensembl:ENSG00000251450 +102546175 LINC01338 HGNC:HGNC:50547|Ensembl:ENSG00000281327 +102546226 LINC02060 HGNC:HGNC:52904|Ensembl:ENSG00000250156 +102546227 LINC01340 HGNC:HGNC:50550|Ensembl:ENSG00000250331 +102546228 LINC02039 HGNC:HGNC:52879|Ensembl:ENSG00000248107 +102546229 LOC102546229 - +102546294 LOC102546294 Ensembl:ENSG00000247199 +102546298 NDST1-AS1 HGNC:HGNC:52899|Ensembl:ENSG00000254333 +102546299 LOC102546299 Ensembl:ENSG00000241956 +102557615 LINC01947 HGNC:HGNC:52771|Ensembl:ENSG00000254130 +102577424 LINC01574 HGNC:HGNC:51388|Ensembl:ENSG00000248859 +102577425 ARHGAP23P1 HGNC:HGNC:45039 +102577426 LINC01962 HGNC:HGNC:52787|Ensembl:ENSG00000248473 +102578074 PCAT5 HGNC:HGNC:48665|Ensembl:ENSG00000280719 +102606462 PRELID2P1 HGNC:HGNC:43892 +102606463 LINC01152 HGNC:HGNC:16752|Ensembl:ENSG00000256124 +102606465 LOC102606465 - +102606466 LOC102606466 - +102659288 KCCAT333 - +102659353 THRIL MIM:615622|HGNC:HGNC:49503|Ensembl:ENSG00000280634 +102682016 LINC01159 HGNC:HGNC:49514|Ensembl:ENSG00000229743 +102723099 GHET1 HGNC:HGNC:49425|Ensembl:ENSG00000281189 +102723100 OTSC10 MIM:615589|HGNC:HGNC:38512 +102723165 LINC01169 HGNC:HGNC:49541|Ensembl:ENSG00000259471 +102723166 STAM-AS1 HGNC:HGNC:49568|Ensembl:ENSG00000260589 +102723167 MIR133A1HG HGNC:HGNC:49594|Ensembl:ENSG00000265142 +102723168 IGHV2-70D HGNC:HGNC:49602|IMGT/GENE-DB:IGHV2-70D +102723169 IGHV1-69D HGNC:HGNC:49601|IMGT/GENE-DB:IGHV1-69D +102723170 IGHV3-64D HGNC:HGNC:49603|IMGT/GENE-DB:IGHV3-64D +102723305 LOC102723305 - +102723312 LOC102723312 - +102723313 LOC102723313 - +102723314 PRELID3BP11 HGNC:HGNC:49073 +102723316 FRG1DP HGNC:HGNC:51763 +102723318 LINC01053 HGNC:HGNC:49047 +102723320 CERS3-AS1 HGNC:HGNC:51431 +102723321 LOC102723321 - +102723322 LOC102723322 Ensembl:ENSG00000260493 +102723323 LOC102723323 - +102723324 LOC102723324 - +102723330 LOC102723330 Ensembl:ENSG00000255335 +102723331 LOC102723331 - +102723332 LINC00412 HGNC:HGNC:42745 +102723333 LOC102723333 - +102723334 LOC102723334 - +102723335 LOC102723335 Ensembl:ENSG00000259540 +102723337 LOC102723337 - +102723338 LOC102723338 - +102723339 LOC102723339 - +102723340 LOC102723340 - +102723341 LOC102723341 - +102723342 LOC102723342 - +102723344 LOC102723344 - +102723345 LOC102723345 - +102723346 HCG21 HGNC:HGNC:31335 +102723347 LOC102723347 - +102723348 LOC102723348 - +102723350 LOC102723350 - +102723354 LINC02298 HGNC:HGNC:53216 +102723356 ZFPM2-AS1 HGNC:HGNC:50698 +102723360 LOC102723360 - +102723362 LINC01884 HGNC:HGNC:52703|Ensembl:ENSG00000233587 +102723364 LOC102723364 - +102723368 LOC102723368 - +102723370 LOC102723370 - +102723373 LOC102723373 Ensembl:ENSG00000261804 +102723376 LOC102723376 - +102723377 CDH23-AS1 HGNC:HGNC:31433|Ensembl:ENSG00000223817 +102723378 LINC01495 HGNC:HGNC:51161|Ensembl:ENSG00000255323 +102723380 LOC102723380 - +102723381 LOC102723381 - +102723382 LOC102723382 - +102723383 LOC102723383 Ensembl:ENSG00000279132|Vega:OTTHUMG00000189300 +102723385 LOC102723385 Ensembl:ENSG00000261465 +102723389 LOC102723389 - +102723390 FRG1EP HGNC:HGNC:51764 +102723392 LOC102723392 - +102723393 LOC102723393 - +102723395 LOC102723395 - +102723396 LOC102723396 - +102723401 LOC102723401 - +102723403 LOC102723403 - +102723406 LOC102723406 - +102723407 LOC102723407 - +102723408 LOC102723408 - +102723409 LOC102723409 - +102723413 LOC102723413 - +102723414 LOC102723414 - +102723415 LOC102723415 - +102723416 CDC27P3 HGNC:HGNC:51754 +102723423 DUX4L25 HGNC:HGNC:50806 +102723426 LINC01496 HGNC:HGNC:51162 +102723427 LOC102723427 Ensembl:ENSG00000225209 +102723430 LOC102723430 - +102723432 LOC102723432 - +102723436 LOC102723436 - +102723438 LOC102723438 - +102723439 LOC102723439 - +102723441 CTD-2154B17.1 - +102723442 LINC01754 HGNC:HGNC:52542 +102723444 LOC102723444 - +102723445 LOC102723445 - +102723446 LOC102723446 - +102723447 LOC102723447 - +102723448 LINC01986 HGNC:HGNC:52817 +102723449 DUX4L24 HGNC:HGNC:50805 +102723451 LOC102723451 Ensembl:ENSG00000277277 +102723458 LOC102723458 - +102723461 LOC102723461 - +102723462 LOC102723462 - +102723464 LOC102723464 - +102723465 ELF3-AS1 HGNC:HGNC:40211 +102723468 LOC102723468 - +102723471 LOC102723471 Ensembl:ENSG00000277268 +102723472 DUX4L23 HGNC:HGNC:50804 +102723475 KCNE1B HGNC:HGNC:52280|Ensembl:ENSG00000276289|Vega:OTTHUMG00000189416 +102723478 LOC102723478 - +102723480 LOC102723480 - +102723481 LINC02206 HGNC:HGNC:53072|Ensembl:ENSG00000259289 +102723483 CSE1L-AS1 HGNC:HGNC:51232|Ensembl:ENSG00000227431 +102723487 LINC01497 HGNC:HGNC:51163|Ensembl:ENSG00000237560 +102723489 LINC00205 HGNC:HGNC:16420 +102723490 LOC102723490 - +102723493 LOC102723493 - +102723495 DUX4L22 HGNC:HGNC:50803 +102723496 LOC102723496 - +102723498 CDC27P4 HGNC:HGNC:51753 +102723502 LOC102723502 Ensembl:ENSG00000276760 +102723505 LINC02095 HGNC:HGNC:52946|Ensembl:ENSG00000228639 +102723506 LOC102723506 - +102723507 LOC102723507 - +102723508 KANTR HGNC:HGNC:49510 +102723509 LOC102723509 - +102723510 LCMT1-AS1 HGNC:HGNC:51177 +102723512 LOC102723512 - +102723513 ZNF30-AS1 HGNC:HGNC:51179 +102723516 LOC102723516 - +102723517 LOC102723517 Ensembl:ENSG00000234899 +102723518 DUX4L21 HGNC:HGNC:50802 +102723525 LINC02498 HGNC:HGNC:53483|Ensembl:ENSG00000283083 +102723526 LINC02218 HGNC:HGNC:53085|Ensembl:ENSG00000249662 +102723528 LOC102723528 - +102723529 LOC102723529 - +102723530 LOC102723530 - +102723532 LOC102723532 Ensembl:ENSG00000274792 +102723533 LOC102723533 - +102723534 LOC102723534 - +102723536 LOC102723536 - +102723538 DUX4L20 HGNC:HGNC:50801 +102723539 LOC102723539 - +102723540 LOC102723540 Ensembl:ENSG00000271109 +102723543 LOC102723543 - +102723544 LOC102723544 Ensembl:ENSG00000255746 +102723546 LOC102723546 - +102723547 CSAG2 HGNC:HGNC:16847|Ensembl:ENSG00000268902 +102723548 LOC102723548 Ensembl:ENSG00000261634 +102723552 ANKRD20A21P HGNC:HGNC:52329 +102723553 SMIM11B HGNC:HGNC:51846|Ensembl:ENSG00000273590|Vega:OTTHUMG00000189412 +102723555 SPDYE16 HGNC:HGNC:51512|Ensembl:ENSG00000185040|Vega:OTTHUMG00000155814 +102723557 LOC102723557 Ensembl:ENSG00000251072 +102723560 LOC102723560 - +102723561 LOC102723561 - +102723562 LINC01498 HGNC:HGNC:51164|Ensembl:ENSG00000247213 +102723564 LOC102723564 - +102723566 LOC102723566 Ensembl:ENSG00000225032 +102723567 LINC02074 HGNC:HGNC:52920 +102723568 LOC102723568 - +102723570 CDC27P9 HGNC:HGNC:51759 +102723573 LOC102723573 - +102723574 HAUS6P3 HGNC:HGNC:50772 +102723575 LOC102723575 - +102723576 LOC102723576 - +102723578 LINC01440 HGNC:HGNC:50762|Ensembl:ENSG00000235166 +102723582 LOC102723582 Ensembl:ENSG00000272758 +102723584 CDC27P10 HGNC:HGNC:51760 +102723585 LOC102723585 - +102723590 BMP7-AS1 HGNC:HGNC:40096 +102723591 LOC102723591 - +102723592 LOC102723592 - +102723594 LOC102723594 - +102723596 LOC102723596 - +102723600 LOC102723600 - +102723603 CDC27P11 HGNC:HGNC:51761 +102723604 LOC102723604 Ensembl:ENSG00000258928 +102723605 LINC01445 HGNC:HGNC:50771|Ensembl:ENSG00000231427 +102723608 LOC102723608 - +102723617 LINC01766 HGNC:HGNC:52556|Ensembl:ENSG00000224910 +102723618 LOC102723618 - +102723619 ATXN2-AS HGNC:HGNC:51838 +102723623 LOC102723623 - +102723624 LOC102723624 - +102723626 TUBB8P8 HGNC:HGNC:42346 +102723629 LOC102723629 - +102723630 LOC102723630 - +102723631 CT45A10 HGNC:HGNC:51263|Ensembl:ENSG00000269586|Vega:OTTHUMG00000022494 +102723632 LOC102723632 - +102723633 LOC102723633 - +102723634 LOC102723634 - +102723635 LOC102723635 - +102723636 LOC102723636 - +102723638 LOC102723638 - +102723639 LOC102723639 - +102723640 LINC02259 HGNC:HGNC:53172|Ensembl:ENSG00000259783 +102723641 HID1-AS1 HGNC:HGNC:51181|Ensembl:ENSG00000263586 +102723644 LINC01499 HGNC:HGNC:51165|Ensembl:ENSG00000255171 +102723647 RPL23AP97 HGNC:HGNC:51632 +102723648 LOC102723648 - +102723649 LOC102723649 - +102723654 LOC102723654 - +102723655 LOC102723655 - +102723656 LOC102723656 - +102723657 LOC102723657 - +102723658 LOC102723658 - +102723660 LOC102723660 - +102723661 LOC102723661 Ensembl:ENSG00000237435 +102723663 LOC102723663 - +102723665 LOC102723665 - +102723668 LOC102723668 - +102723670 LOC102723670 - +102723672 LOC102723672 - +102723675 LOC102723675 - +102723678 LOC102723678 - +102723680 CT45A9 HGNC:HGNC:51262|Ensembl:ENSG00000270946|Vega:OTTHUMG00000188606 +102723681 LOC102723681 - +102723684 LOC102723684 - +102723686 LOC102723686 - +102723688 LOC102723688 - +102723689 LOC102723689 - +102723690 LOC102723690 - +102723692 LOC102723692 Ensembl:ENSG00000261448 +102723694 LOC102723694 - +102723696 LOC102723696 - +102723699 LINC02284 HGNC:HGNC:53201 +102723701 LOC102723701 Ensembl:ENSG00000183154 +102723703 LOC102723703 - +102723704 LOC102723704 - +102723706 LOC102723706 - +102723708 LOC102723708 - +102723709 LOC102723709 - +102723711 CDC27P7 HGNC:HGNC:51757 +102723713 LOC102723713 - +102723714 LOC102723714 - +102723716 LOC102723716 - +102723722 LOC102723722 - +102723724 LOC102723724 - +102723725 LOC102723725 - +102723727 LOC102723727 Ensembl:ENSG00000229258 +102723728 LOC102723728 Ensembl:ENSG00000185164 +102723729 LOC102723729 - +102723730 LOC102723730 - +102723733 LOC102723733 - +102723737 CT45A8 HGNC:HGNC:51261|Ensembl:ENSG00000278085|Vega:OTTHUMG00000188605 +102723739 LOC102723739 - +102723740 LOC102723740 - +102723741 LOC102723741 - +102723742 LINC01500 HGNC:HGNC:51166|Ensembl:ENSG00000258583 +102723748 LOC102723748 - +102723749 LOC102723749 - +102723750 LOC102723750 - +102723752 LOC102723752 - +102723753 LOC102723753 - +102723757 LOC102723757 - +102723758 LOC102723758 - +102723759 LOC102723759 - +102723760 LOC102723760 - +102723761 LOC102723761 - +102723763 LOC102723763 - +102723764 LINC02364 HGNC:HGNC:53288 +102723765 LOC102723765 - +102723766 LINC02362 HGNC:HGNC:53284|Ensembl:ENSG00000249096 +102723769 LOC102723769 - +102723775 LINC01315 HGNC:HGNC:50513|Ensembl:ENSG00000229891 +102723776 LOC102723776 - +102723777 LOC102723777 - +102723778 LINC02497 HGNC:HGNC:53482|Ensembl:ENSG00000251182 +102723780 LOC102723780 - +102723782 LOC102723782 - +102723784 LOC102723784 - +102723786 LOC102723786 Ensembl:ENSG00000261260 +102723789 LOC102723789 - +102723791 LOC102723791 - +102723795 LOC102723795 - +102723796 LOC102723796 - +102723798 LOC102723798 - +102723803 LOC102723803 - +102723805 LOC102723805 - +102723806 LOC102723806 - +102723809 LOC102723809 Ensembl:ENSG00000259116 +102723811 LOC102723811 - +102723814 LOC102723814 - +102723815 LOC102723815 - +102723817 LOC102723817 - +102723818 LINC01248 HGNC:HGNC:49842 +102723819 LOC102723819 - +102723822 LOC102723822 - +102723824 LOC102723824 - +102723825 LOC102723825 - +102723828 LINC02506 HGNC:HGNC:53495|Ensembl:ENSG00000251129 +102723831 LOC102723831 - +102723833 LOC102723833 Ensembl:ENSG00000233620 +102723834 LOC102723834 - +102723838 LOC102723838 Ensembl:ENSG00000255482 +102723839 LINC02224 HGNC:HGNC:53093 +102723840 LOC102723840 - +102723841 LOC102723841 - +102723842 LOC102723842 - +102723846 LOC102723846 - +102723847 LOC102723847 - +102723849 SPDYE17 HGNC:HGNC:51513 +102723850 LOC102723850 - +102723851 LOC102723851 - +102723852 TPT1P7 HGNC:HGNC:49300 +102723854 LINC01819 HGNC:HGNC:52624|Ensembl:ENSG00000231826 +102723855 LOC102723855 - +102723859 TBC1D3E MIM:610808|HGNC:HGNC:27071|Ensembl:ENSG00000278599|Vega:OTTHUMG00000188486 +102723862 LOC102723862 - +102723869 LOC102723869 - +102723870 LOC102723870 - +102723872 LOC102723872 - +102723875 LINC01065 HGNC:HGNC:49103 +102723876 LOC102723876 - +102723878 LOC102723878 - +102723879 LOC102723879 - +102723883 LOC102723883 Ensembl:ENSG00000223504 +102723885 LOC102723885 - +102723886 LOC102723886 - +102723890 LOC102723890 - +102723895 LINC02552 HGNC:HGNC:53587|Ensembl:ENSG00000256422 +102723896 LOC102723896 - +102723897 LOC102723897 - +102723899 LOC102723899 - +102723904 LOC102723904 - +102723906 LOC102723906 - +102723910 LOC102723910 - +102723911 LOC102723911 - +102723914 LOC102723914 - +102723915 LOC102723915 - +102723917 LOC102723917 - +102723920 LINC02515 HGNC:HGNC:53504 +102723922 LOC102723922 - +102723924 LOC102723924 - +102723927 LINC01238 HGNC:HGNC:49795|Ensembl:ENSG00000237940 +102723930 LOC102723930 - +102723932 LOC102723932 - +102723933 LOC102723933 - +102723934 LOC102723934 - +102723935 LOC102723935 - +102723944 LOC102723944 - +102723945 LOC102723945 - +102723948 LOC102723948 - +102723952 LOC102723952 - +102723955 LOC102723955 - +102723961 LOC102723961 - +102723963 LOC102723963 - +102723964 LOC102723964 - +102723966 LOC102723966 - +102723967 LOC102723967 - +102723968 LOC102723968 Ensembl:ENSG00000219926 +102723971 LOC102723971 Ensembl:ENSG00000236543|Vega:OTTHUMG00000153545 +102723977 UBE2V1P11 HGNC:HGNC:44896 +102723981 RPL23AP84 HGNC:HGNC:51575 +102723983 LOC102723983 - +102723985 LOC102723985 - +102723989 LOC102723989 - +102723991 LOC102723991 - +102723994 LOC102723994 - +102723996 LOC102723996 Ensembl:ENSG00000277117|Vega:OTTHUMG00000189355 +102723999 LOC102723999 - +102724000 LINC01626 HGNC:HGNC:52257 +102724001 LOC102724001 - +102724008 LOC102724008 - +102724009 LOC102724009 Ensembl:ENSG00000227495 +102724014 LOC102724014 - +102724015 LOC102724015 - +102724017 LOC102724017 - +102724018 FRG2KP HGNC:HGNC:51797|Ensembl:ENSG00000261741 +102724019 LOC102724019 - +102724020 LOC102724020 Ensembl:ENSG00000256803 +102724023 LOC102724023 Ensembl:ENSG00000280071|Vega:OTTHUMG00000189357 +102724025 LOC102724025 - +102724027 LOC102724027 - +102724030 LOC102724030 - +102724031 LOC102724031 - +102724034 LOC102724034 - +102724035 NDUFA5P2 HGNC:HGNC:48855 +102724036 LOC102724036 - +102724039 LOC102724039 - +102724042 LOC102724042 - +102724046 LOC102724046 - +102724047 WWOX-AS1 HGNC:HGNC:53169 +102724048 LOC102724048 - +102724050 LOC102724050 Ensembl:ENSG00000258137 +102724052 LOC102724052 - +102724053 LINC02529 HGNC:HGNC:53555|Ensembl:ENSG00000234777 +102724055 LOC102724055 - +102724057 LOC102724057 - +102724058 LOC102724058 Ensembl:ENSG00000236107 +102724062 LOC102724062 - +102724064 LOC102724064 Ensembl:ENSG00000255468 +102724066 LOC102724066 - +102724068 LOC102724068 - +102724070 LOC102724070 - +102724072 LOC102724072 - +102724076 LINC01038 HGNC:HGNC:49026|Ensembl:ENSG00000229011 +102724077 LINC01389 HGNC:HGNC:50661 +102724078 LOC102724078 - +102724080 LOC102724080 - +102724081 LOC102724081 - +102724082 LOC102724082 - +102724084 LOC102724084 - +102724087 LOC102724087 - +102724092 LOC102724092 - +102724093 LOC102724093 - +102724094 LOC102724094 Ensembl:ENSG00000227053 +102724096 LOC102724096 - +102724097 TTC39A-AS1 HGNC:HGNC:40851|Ensembl:ENSG00000261664 +102724100 LOC102724100 - +102724101 TP53TG3E HGNC:HGNC:51816|Ensembl:ENSG00000275034|Vega:OTTHUMG00000189337 +102724102 LOC102724102 - +102724104 LOC102724104 - +102724105 ZNF528-AS1 HGNC:HGNC:51305|Ensembl:ENSG00000269834 +102724117 LOC102724117 - +102724120 LOC102724120 - +102724122 LOC102724122 - +102724124 LOC102724124 - +102724127 TP53TG3F HGNC:HGNC:51817|Ensembl:ENSG00000278848|Vega:OTTHUMG00000189349 +102724130 LINC02564 HGNC:HGNC:53604 +102724133 LOC102724133 - +102724135 LOC102724135 - +102724139 LOC102724139 - +102724142 LOC102724142 - +102724143 LOC102724143 - +102724145 LOC102724145 - +102724146 LOC102724146 - +102724148 LOC102724148 - +102724149 LOC102724149 - +102724150 LOC102724150 - +102724152 LOC102724152 - +102724153 LOC102724153 Ensembl:ENSG00000224721 +102724156 LOC102724156 - +102724158 LOC102724158 - +102724159 LOC102724159 Ensembl:ENSG00000275464|Vega:OTTHUMG00000189361 +102724163 LOC102724163 Ensembl:ENSG00000260228 +102724165 LOC102724165 - +102724167 PABPC5-AS1 HGNC:HGNC:31845|Ensembl:ENSG00000234161 +102724168 LINC02542 HGNC:HGNC:53576 +102724178 LOC102724178 - +102724181 LOC102724181 - +102724183 LOC102724183 - +102724184 LOC102724184 - +102724188 LINC01674 HGNC:HGNC:52462|Ensembl:ENSG00000228159 +102724190 LINC02289 HGNC:HGNC:53205|Ensembl:ENSG00000258819 +102724191 LOC102724191 - +102724193 LOC102724193 - +102724194 LOC102724194 - +102724197 LOC102724197 - +102724200 LOC102724200 Ensembl:ENSG00000280433|Vega:OTTHUMG00000189362 +102724201 TBX18-AS1 HGNC:HGNC:52256|Ensembl:ENSG00000228290 +102724202 LOC102724202 - +102724207 LOC102724207 - +102724208 LINC01900 HGNC:HGNC:52719|Ensembl:ENSG00000265758 +102724210 LOC102724210 - +102724211 LOC102724211 - +102724214 LOC102724214 - +102724216 LOC102724216 - +102724219 LOC102724219 - +102724220 LOC102724220 - +102724222 LOC102724222 - +102724223 LOC102724223 - +102724224 LINC01117 HGNC:HGNC:49260|Ensembl:ENSG00000224577 +102724227 LOC102724227 - +102724229 LOC102724229 - +102724231 LINC00694 HGNC:HGNC:44570|Ensembl:ENSG00000225873|Vega:OTTHUMG00000156179 +102724233 LOC102724233 - +102724234 LOC102724234 - +102724236 LOC102724236 - +102724237 LOC102724237 - +102724238 LOC102724238 - +102724245 LOC102724245 - +102724246 TTC39C-AS1 HGNC:HGNC:51321|Ensembl:ENSG00000264745 +102724250 LOC102724250 Ensembl:ENSG00000271254 +102724253 LOC102724253 - +102724261 LOC102724261 - +102724262 LOC102724262 - +102724264 LOC102724264 Ensembl:ENSG00000234973 +102724265 LOC102724265 - +102724269 LOC102724269 - +102724273 LOC102724273 - +102724279 LINC01835 HGNC:HGNC:52651 +102724288 LOC102724288 - +102724289 LOC102724289 - +102724290 LOC102724290 - +102724294 LINC02311 HGNC:HGNC:53230 +102724297 LOC102724297 - +102724301 LOC102724301 Ensembl:ENSG00000254854 +102724307 CYP17A1-AS1 HGNC:HGNC:31671|Ensembl:ENSG00000203886 +102724312 LINC01770 HGNC:HGNC:52560 +102724316 SVIL-AS1 HGNC:HGNC:51219|Ensembl:ENSG00000224597 +102724319 LOC102724319 - +102724321 LINC01628 HGNC:HGNC:52259|Ensembl:ENSG00000232688 +102724322 LOC102724322 - +102724323 LOC102724323 Ensembl:ENSG00000231964 +102724327 LOC102724327 - +102724329 LOC102724329 - +102724330 LOC102724330 - +102724333 LOC102724333 - +102724334 LOC102724334 Ensembl:ENSG00000274559 +102724338 LINC02305 HGNC:HGNC:53224 +102724339 CTB-30L5.1 - +102724340 LOC102724340 - +102724341 NEURL1-AS1 HGNC:HGNC:51220|Ensembl:ENSG00000235470 +102724344 LINC02188 HGNC:HGNC:53050|Ensembl:ENSG00000261175 +102724345 LOC102724345 - +102724350 LOC102724350 - +102724351 LOC102724351 - +102724354 LINC01669 HGNC:HGNC:52457|Ensembl:ENSG00000280191 +102724355 LOC102724355 - +102724357 LOC102724357 Ensembl:ENSG00000234519 +102724358 LOC102724358 - +102724360 LOC102724360 Ensembl:ENSG00000269019 +102724362 SPINT1-AS1 HGNC:HGNC:53162|Ensembl:ENSG00000261183 +102724363 LOC102724363 - +102724364 LOC102724364 - +102724365 LOC102724365 - +102724368 CELSR3-AS1 HGNC:HGNC:50302|Ensembl:ENSG00000228350 +102724370 LOC102724370 - +102724373 LOC102724373 Ensembl:ENSG00000224173 +102724378 LOC102724378 - +102724379 LOC102724379 - +102724380 LINC02316 HGNC:HGNC:53235 +102724382 LOC102724382 - +102724386 LINC01393 HGNC:HGNC:50669|Ensembl:ENSG00000225535 +102724389 LOC102724389 - +102724392 LINC02197 HGNC:HGNC:53063 +102724393 LOC102724393 - +102724397 LOC102724397 - +102724398 CH507-42P11.6 - +102724404 LOC102724404 Ensembl:ENSG00000251405 +102724406 LOC102724406 - +102724407 LOC102724407 - +102724410 LOC102724410 - +102724416 LOC102724416 - +102724417 LOC102724417 - +102724419 LOC102724419 - +102724420 LOC102724420 - +102724421 LOC102724421 Ensembl:ENSG00000257083 +102724422 LOC102724422 - +102724427 LOC102724427 - +102724428 LOC102724428 Ensembl:ENSG00000275993|Vega:OTTHUMG00000189394 +102724429 LOC102724429 - +102724430 KRT8P50 HGNC:HGNC:48346 +102724431 LOC102724431 - +102724433 LINC02420 HGNC:HGNC:53350 +102724434 LOC102724434 Ensembl:ENSG00000237870 +102724437 LOC102724437 - +102724438 LOC102724438 - +102724439 LOC102724439 - +102724443 LOC102724443 - +102724444 LOC102724444 - +102724446 LOC102724446 - +102724447 LOC102724447 - +102724449 LOC102724449 - +102724450 LOC102724450 Ensembl:ENSG00000226944 +102724452 LOC102724452 Ensembl:ENSG00000259620 +102724458 LOC102724458 - +102724459 LOC102724459 - +102724463 LOC102724463 - +102724465 LOC102724465 - +102724467 LOC102724467 - +102724468 LOC102724468 - +102724470 LINC01887 HGNC:HGNC:52706 +102724473 GAGE10 MIM:300737|HGNC:HGNC:30968|Ensembl:ENSG00000215274|Vega:OTTHUMG00000024136 +102724474 LOC102724474 - +102724475 LOC102724475 - +102724479 LOC102724479 - +102724481 LINC01702 HGNC:HGNC:52490 +102724482 LOC102724482 - +102724484 LOC102724484 - +102724485 LOC102724485 - +102724488 LOC102724488 Ensembl:ENSG00000277758|Vega:OTTHUMG00000189287 +102724489 LOC102724489 - +102724491 LOC102724491 - +102724495 LOC102724495 - +102724497 LOC102724497 - +102724502 LINC01690 HGNC:HGNC:52477|Ensembl:ENSG00000228961 +102724507 LOC102724507 - +102724508 THCAT158 Ensembl:ENSG00000263293 +102724509 LOC102724509 - +102724510 LOC102724510 - +102724511 LOC102724511 - +102724515 LINC01291 HGNC:HGNC:50358|Ensembl:ENSG00000204792 +102724517 LOC102724517 - +102724520 LOC102724520 - +102724521 LOC102724521 - +102724523 LOC102724523 - +102724525 LOC102724525 - +102724526 LOC102724526 - +102724527 LOC102724527 - +102724528 LOC102724528 - +102724530 LOC102724530 - +102724532 LOC102724532 Ensembl:ENSG00000264920 +102724533 LOC102724533 - +102724536 PRR33 HGNC:HGNC:35118 +102724539 LINC01714 HGNC:HGNC:52501|Ensembl:ENSG00000227634 +102724542 LOC102724542 - +102724545 LOC102724545 - +102724547 LOC102724547 - +102724548 LOC102724548 - +102724550 LINC02015 HGNC:HGNC:52850|Ensembl:ENSG00000231574 +102724551 LOC102724551 - +102724552 LOC102724552 - +102724553 LOC102724553 - +102724555 LOC102724555 Ensembl:ENSG00000230442 +102724557 LOC102724557 - +102724560 CBSL HGNC:HGNC:51829|Ensembl:ENSG00000274276|Vega:OTTHUMG00000189375 +102724562 LOC102724562 - +102724563 LOC102724563 - +102724566 LOC102724566 - +102724571 LINC01759 HGNC:HGNC:52548|Ensembl:ENSG00000234546 +102724572 LOC102724572 - +102724577 LOC102724577 - +102724579 LOC102724579 - +102724580 LOC102724580 - +102724584 LOC102724584 - +102724586 LOC102724586 - +102724587 LOC102724587 - +102724589 LOC102724589 Ensembl:ENSG00000236799 +102724591 LOC102724591 - +102724593 LOC102724593 - +102724594 U2AF1L5 HGNC:HGNC:51830|Ensembl:ENSG00000275895|Vega:OTTHUMG00000189373 +102724596 LOC102724596 Ensembl:ENSG00000248714 +102724601 LOC102724601 Ensembl:ENSG00000227373 +102724602 LOC102724602 - +102724603 LOC102724603 - +102724604 LOC102724604 Ensembl:ENSG00000241231 +102724605 UBE2V1P10 HGNC:HGNC:44895 +102724608 LOC102724608 - +102724612 LOC102724612 Ensembl:ENSG00000253894 +102724615 LOC102724615 - +102724617 LINC02031 HGNC:HGNC:52865 +102724618 LOC102724618 - +102724621 LOC102724621 - +102724623 LOC102724623 Ensembl:ENSG00000253554 +102724624 LOC102724624 - +102724625 LOC102724625 - +102724627 LOC102724627 - +102724631 POTEB3 HGNC:HGNC:51240|Ensembl:ENSG00000278522|Vega:OTTHUMG00000189222 +102724632 LOC102724632 - +102724634 LOC102724634 - +102724636 LOC102724636 - +102724637 LOC102724637 - +102724638 LOC102724638 - +102724642 LOC102724642 - +102724643 LOC102724643 - +102724645 LOC102724645 - +102724646 LOC102724646 - +102724651 LINC01919 HGNC:HGNC:52739|Ensembl:ENSG00000263438 +102724652 LOC102724652 Ensembl:ENSG00000276076|Vega:OTTHUMG00000189395 +102724653 LOC102724653 - +102724655 AQP7P5 HGNC:HGNC:51836 +102724657 LOC102724657 - +102724659 LOC102724659 Ensembl:ENSG00000177553 +102724660 LOC102724660 - +102724661 LINC01645 HGNC:HGNC:52432 +102724663 PPFIA2-AS1 HGNC:HGNC:53397|Ensembl:ENSG00000257467 +102724665 LOC102724665 - +102724668 DPY19L1P2 HGNC:HGNC:22851 +102724670 LOC102724670 - +102724672 LOC102724672 - +102724677 LOC102724677 - +102724678 LINC01423 HGNC:HGNC:50732 +102724679 LINC02556 HGNC:HGNC:53595 +102724680 LOC102724680 - +102724682 LOC102724682 - +102724683 LOC102724683 - +102724684 LOC102724684 Ensembl:ENSG00000267026 +102724687 LOC102724687 - +102724689 LOC102724689 - +102724691 LOC102724691 Ensembl:ENSG00000224509 +102724698 LINC01905 HGNC:HGNC:52724 +102724699 LINC02043 HGNC:HGNC:52883|Ensembl:ENSG00000232233 +102724700 LOC102724700 - +102724701 LOC102724701 Ensembl:ENSG00000275496 +102724706 UBE2V1P8 HGNC:HGNC:44893 +102724708 LOC102724708 - +102724710 LOC102724710 Ensembl:ENSG00000253634 +102724711 LOC102724711 - +102724714 LINC01857 HGNC:HGNC:52673|Ensembl:ENSG00000224137 +102724715 LOC102724715 - +102724719 LOC102724719 Ensembl:ENSG00000223502 +102724720 LOC102724720 - +102724723 LOC102724723 - +102724726 LOC102724726 - +102724727 LOC102724727 - +102724728 LOC102724728 - +102724731 LOC102724731 - +102724732 LOC102724732 - +102724734 LOC102724734 - +102724736 LOC102724736 - +102724737 LOC102724737 - +102724738 LOC102724738 - +102724740 LOC102724740 - +102724742 PRAMEF28P HGNC:HGNC:51890 +102724744 LOC102724744 - +102724745 LOC102724745 - +102724748 LOC102724748 - +102724749 LOC102724749 - +102724750 LOC102724750 - +102724751 LOC102724751 - +102724754 LOC102724754 - +102724760 LOC102724760 - +102724761 LOC102724761 - +102724763 LINC02040 HGNC:HGNC:52880 +102724765 LOC102724765 - +102724768 LOC102724768 - +102724770 LOC102724770 Ensembl:ENSG00000278817 +102724772 LOC102724772 - +102724773 LOC102724773 - +102724774 LINC01594 HGNC:HGNC:51584|Ensembl:ENSG00000225328 +102724775 LOC102724775 - +102724776 LOC102724776 Ensembl:ENSG00000250910 +102724777 LOC102724777 - +102724778 LOC102724778 - +102724780 LOC102724780 - +102724784 LOC102724784 - +102724785 LOC102724785 - +102724787 LOC102724787 - +102724788 LOC102724788 Ensembl:ENSG00000277196 +102724793 LOC102724793 - +102724800 LOC102724800 - +102724801 LOC102724801 - +102724802 LOC102724802 - +102724804 LOC102724804 Ensembl:ENSG00000253105 +102724805 LOC102724805 - +102724808 LOC102724808 - +102724810 LINC02062 HGNC:HGNC:52907 +102724813 LOC102724813 - +102724814 LOC102724814 Ensembl:ENSG00000258727 +102724816 UBE2V1P4 HGNC:HGNC:44886 +102724817 LOC102724817 - +102724818 LOC102724818 - +102724820 LANCL1-AS1 HGNC:HGNC:50727 +102724822 LOC102724822 - +102724823 LOC102724823 - +102724826 ZNF337-AS1 HGNC:HGNC:40759|Ensembl:ENSG00000213742 +102724827 MIATNB HGNC:HGNC:50731 +102724830 LOC102724830 - +102724832 LOC102724832 - +102724834 LOC102724834 - +102724838 LOC102724838 - +102724843 LOC102724843 - +102724845 LINC00596 HGNC:HGNC:23167 +102724846 LOC102724846 - +102724847 LOC102724847 - +102724848 LOC102724848 - +102724849 LOC102724849 Ensembl:ENSG00000225166 +102724850 LOC102724850 - +102724851 LOC102724851 - +102724852 LOC102724852 - +102724853 NDUFA5P10 HGNC:HGNC:48852 +102724855 LINC02113 HGNC:HGNC:52967 +102724856 LOC102724856 - +102724857 LOC102724857 - +102724858 LOC102724858 - +102724859 LOC102724859 - +102724861 LOC102724861 - +102724862 TBC1D3I HGNC:HGNC:32709|Ensembl:ENSG00000274933|Vega:OTTHUMG00000188424 +102724863 LOC102724863 - +102724865 LOC102724865 - +102724866 NDUFA5P11 HGNC:HGNC:48853 +102724868 TPT1P11 HGNC:HGNC:49302 +102724874 LOC102724874 - +102724875 LOC102724875 - +102724877 LOC102724877 - +102724880 LOC102724880 - +102724881 LOC102724881 - +102724883 LOC102724883 - +102724886 LOC102724886 - +102724889 LOC102724889 Ensembl:ENSG00000272009 +102724890 LINC02293 HGNC:HGNC:53209|Ensembl:ENSG00000257185 +102724892 LOC102724892 - +102724895 LIVAR HGNC:HGNC:53130 +102724897 LOC102724897 - +102724900 LOC102724900 - +102724902 LOC102724902 - +102724903 LOC102724903 - +102724904 LOC102724904 - +102724906 LOC102724906 - +102724907 LOC102724907 - +102724908 LOC102724908 Ensembl:ENSG00000266976 +102724913 LINC01899 HGNC:HGNC:52718|Ensembl:ENSG00000265352 +102724916 LOC102724916 - +102724917 LINC02327 HGNC:HGNC:53247 +102724919 LOC102724919 Ensembl:ENSG00000229739 +102724922 LOC102724922 - +102724923 FRG1KP HGNC:HGNC:51769 +102724927 LOC102724927 Ensembl:ENSG00000262185 +102724928 CCNYL3 HGNC:HGNC:33206 +102724929 LOC102724929 - +102724933 LINC02412 HGNC:HGNC:53341|Ensembl:ENSG00000258171 +102724934 LOC102724934 - +102724937 LOC102724937 - +102724938 LOC102724938 - +102724940 LINC02187 HGNC:HGNC:53049|Ensembl:ENSG00000263082 +102724943 LOC102724943 - +102724945 LOC102724945 - +102724946 LOC102724946 - +102724948 LOC102724948 - +102724949 LOC102724949 - +102724950 LOC102724950 - +102724951 LOC102724951 - +102724954 LINC01032 HGNC:HGNC:49018 +102724955 LOC102724955 - +102724956 LOC102724956 - +102724957 LOC102724957 - +102724958 LOC102724958 - +102724960 LOC102724960 - +102724962 LOC102724962 - +102724965 LOC102724965 - +102724968 LOC102724968 - +102724971 LOC102724971 - +102724977 LOC102724977 - +102724979 LOC102724979 - +102724983 LOC102724983 - +102724984 LOC102724984 - +102724985 LOC102724985 - +102724992 LOC102724992 - +102724993 LOC102724993 - +102724994 LOC102724994 - +102724995 LOC102724995 - +102724999 LOC102724999 - +102725000 LOC102725000 - +102725003 LOC102725003 - +102725009 LOC102725009 - +102725019 LOC102725019 - +102725021 LOC102725021 - +102725022 LINC02352 HGNC:HGNC:53274 +102725023 LOC102725023 - +102725034 LOC102725034 - +102725035 LOC102725035 - +102725044 LOC102725044 - +102725045 NOVA1-AS1 HGNC:HGNC:19827 +102725046 LOC102725046 - +102725048 LOC102725048 - +102725051 LOC102725051 - +102725065 LOC102725065 - +102725068 LOC102725068 - +102725069 LOC102725069 - +102725070 LOC102725070 - +102725072 LOC102725072 Ensembl:ENSG00000161103 +102725078 LOC102725078 - +102725079 LINC01878 HGNC:HGNC:52697|Ensembl:ENSG00000234308 +102725080 LOC102725080 - +102725082 LOC102725082 - +102725101 LOC102725101 - +102725104 LOC102725104 - +102725105 CDH18-AS1 HGNC:HGNC:53088 +102725112 LOC102725112 - +102725114 LOC102725114 - +102725115 LOC102725115 - +102725116 LOC102725116 - +102725117 LOC102725117 - +102725118 LOC102725118 - +102725121 LOC102725121 - +102725126 LOC102725126 - +102725138 LOC102725138 - +102725139 LOC102725139 - +102725140 LOC102725140 - +102725144 LOC102725144 - +102725145 LOC102725145 - +102725148 LOC102725148 - +102725156 LOC102725156 - +102725159 LOC102725159 - +102725165 LOC102725165 - +102725168 LOC102725168 - +102725176 LINC01595 HGNC:HGNC:51586 +102725179 LOC102725179 - +102725180 LOC102725180 - +102725191 LOC102725191 Ensembl:ENSG00000226690 +102725193 LOC102725193 - +102725195 LOC102725195 - +102725201 LOC102725201 - +102725207 LOC102725207 - +102725209 LOC102725209 - +102725220 LOC102725220 - +102725227 LOC102725227 - +102725228 LOC102725228 - +102725231 LOC102725231 - +102725238 LOC102725238 - +102725239 LOC102725239 - +102725241 LOC102725241 - +102725250 LOC102725250 - +102725254 LOC102725254 Ensembl:ENSG00000268650 +102725258 LOC102725258 - +102725509 LINC01232 HGNC:HGNC:49755 +102725532 LOC102725532 Ensembl:ENSG00000236951 +102725541 ELDR HGNC:HGNC:49511 +102775565 MRX92 MIM:300851 +102775567 DDH2 MIM:615612 +102775568 MRX95 MIM:300716 +102800310 HAGLROS HGNC:HGNC:50646 +102800311 TP53COR1 MIM:616343|HGNC:HGNC:43652 +102800314 MIR7515HG HGNC:HGNC:49838|Ensembl:ENSG00000236172 +102800315 LINC01246 HGNC:HGNC:49840|Ensembl:ENSG00000236172 +102800316 LINC01222 HGNC:HGNC:49672 +102800317 LOC400927-CSNK1E Ensembl:ENSG00000283900|Vega:OTTHUMG00000151135 +102800446 LINC01230 HGNC:HGNC:49686 +102800447 LINC01828 HGNC:HGNC:52634 +102902672 LINC00843 HGNC:HGNC:45009 +102929163 LOC102929163 - +102997063 DEL15Q11.2 MIM:615656 +102997064 DEL5Q12 MIM:615668 +102997065 DDD3 MIM:615674 +103021164 CASC21 HGNC:HGNC:49836 +103021165 CASC19 HGNC:HGNC:49476 +103021294 ABALON MIM:616018|HGNC:HGNC:49667|Ensembl:ENSG00000281376 +103021295 LOC103021295 - +103021296 LOC103021296 - +103047893 LOC103047893 - +103091863 NDUFA5P8 HGNC:HGNC:48850 +103091864 SNHG22 HGNC:HGNC:50285|Ensembl:ENSG00000267322 +103091865 BRWD1-IT2 Ensembl:ENSG00000255568 +103091866 LOC103091866 Ensembl:ENSG00000272419 +103106900 TRBVC HGNC:HGNC:50321|IMGT/GENE-DB:TRBVC +103106901 IGHV3-43D HGNC:HGNC:50322|IMGT/GENE-DB:IGHV3-43D +103106902 ETL6 MIM:615697 +103106903 LINC01276 HGNC:HGNC:50333|Ensembl:ENSG00000226917 +103156999 LOC103156999 - +103157000 PAUPAR HGNC:HGNC:49670|Ensembl:ENSG00000281880 +103164619 PCAT2 HGNC:HGNC:45089|Ensembl:ENSG00000253264 +103171572 DUP8Q22.1 MIM:151200 +103171574 LOC103171574 Ensembl:ENSG00000259774 +103191607 LINC02333 HGNC:HGNC:53253|Ensembl:ENSG00000271564 +103283057 LINC01362 HGNC:HGNC:50596 +103312105 LOC103312105 Ensembl:ENSG00000255175 +103344718 HOTS - +103344926 LINCR-0002 - +103344927 FRIASS MIM:609640 +103344928 KIAA1614-AS1 HGNC:HGNC:50644 +103344929 BGLT3 MIM:616308|HGNC:HGNC:49033|Ensembl:ENSG00000260629 +103344930 LINC01391 HGNC:HGNC:50666|Ensembl:ENSG00000244578 +103344931 LOC103344931 Ensembl:ENSG00000260917 +103344932 PGM5P4-AS1 HGNC:HGNC:51195|Ensembl:ENSG00000231943 +103352539 LINC01410 HGNC:HGNC:50702|Ensembl:ENSG00000238113 +103352540 IGKV1OR9-1 HGNC:HGNC:49473|IMGT/GENE-DB:IGKV1/OR9-1 +103352541 LOC103352541 - +103352670 LINC01419 HGNC:HGNC:50712|Ensembl:ENSG00000253898 +103456505 TRG-CCC1-1 HGNC:HGNC:38580 +103456506 TRE-TTC4-1 HGNC:HGNC:38581 +103456507 LINC01442 HGNC:HGNC:50764|Ensembl:ENSG00000227510 +103456508 TRC-GCA7-1 HGNC:HGNC:38575 +103456509 TRN-GTT18-1 HGNC:HGNC:50799 +103456510 TRV-CAC11-1 HGNC:HGNC:38578 +103456511 TRL-CAA1-1 HGNC:HGNC:38583 +103482523 TRUND-NNN2-1 HGNC:HGNC:50814 +103482524 TRUND-NNN5-1 HGNC:HGNC:50817 +103482525 TRUND-NNN6-1 HGNC:HGNC:50818 +103482526 TRUND-NNN9-1 HGNC:HGNC:50821 +103482527 TRUND-NNN3-1 HGNC:HGNC:50815 +103482528 TRUND-NNN8-1 HGNC:HGNC:50820 +103482529 TRUND-NNN1-1 HGNC:HGNC:50813 +103482530 TRUND-NNN4-1 HGNC:HGNC:50816 +103482531 TRUND-NNN7-1 HGNC:HGNC:50819 +103482532 TRUND-NNN10-1 HGNC:HGNC:50822 +103504726 MIR3670-3 HGNC:HGNC:50829|Ensembl:ENSG00000265776|miRBase:MI0031513 +103504727 MIR6724-2 HGNC:HGNC:50832|Ensembl:ENSG00000274060|miRBase:MI0031516 +103504728 MIR3687-2 HGNC:HGNC:50835|Ensembl:ENSG00000264063|miRBase:MI0031515 +103504729 MIR3179-4 HGNC:HGNC:50838|Ensembl:ENSG00000277014|miRBase:MI0031510 +103504730 MIR9500 HGNC:HGNC:50841|Ensembl:ENSG00000283639|miRBase:MI0029185 +103504731 MIR3648-2 HGNC:HGNC:50843|Ensembl:ENSG00000264462|miRBase:MI0031512 +103504732 MIR941-5 HGNC:HGNC:50845|Ensembl:ENSG00000275842|miRBase:MI0031520 +103504733 MIR6724-4 HGNC:HGNC:50830|Ensembl:ENSG00000275692|miRBase:MI0031518 +103504734 MIR1244-4 HGNC:HGNC:50831|Ensembl:ENSG00000283475|miRBase:MI0031511 +103504735 MIR548BB HGNC:HGNC:50834|Ensembl:ENSG00000281426|miRBase:MI0029321 +103504736 MIR8069-2 HGNC:HGNC:50836|Ensembl:ENSG00000278618|miRBase:MI0031519 +103504737 MIR8485 HGNC:HGNC:50839|Ensembl:ENSG00000216191|miRBase:MI0027288 +103504738 MIR6859-4 HGNC:HGNC:50840|Ensembl:ENSG00000278739|miRBase:MI0031521 +103504739 MIR6724-3 HGNC:HGNC:50842|Ensembl:ENSG00000277379|miRBase:MI0031517 +103504740 MIR3670-4 HGNC:HGNC:50828|Ensembl:ENSG00000274025|miRBase:MI0031514 +103504741 MIR5701-3 HGNC:HGNC:50844|Ensembl:ENSG00000264902|miRBase:MI0031522 +103539957 ERVK-26 HGNC:HGNC:44979 +103539958 TRG-CCC8-1 HGNC:HGNC:50798 +103568124 LOC103568124 - +103581030 TRN-ATT1-2 HGNC:HGNC:50812 +103581031 CASC23 HGNC:HGNC:50865|Ensembl:ENSG00000255420 +103581096 OFC14 MIM:615892 +103611079 ASOBS MIM:615835 +103611081 LOC103611081 Ensembl:ENSG00000255455 +103611090 CDR1-AS HGNC:HGNC:48926 +103611155 PAPPA-AS2 HGNC:HGNC:35160 +103611157 TGFB2-OT1 HGNC:HGNC:50629|Ensembl:ENSG00000281453 +103625681 LLPH-AS1 HGNC:HGNC:50493|Ensembl:ENSG00000239335 +103625683 LINC00456 HGNC:HGNC:42804|Ensembl:ENSG00000233124 +103625684 RNU6-2 HGNC:HGNC:34270|Ensembl:ENSG00000207357 +103689843 LINC01046 HGNC:HGNC:49040|Ensembl:ENSG00000233405 +103689844 LINC01288 HGNC:HGNC:50353|Ensembl:ENSG00000254344 +103689845 LINC01050 HGNC:HGNC:49044|Ensembl:ENSG00000271216 +103689846 ADAMTS19-AS1 HGNC:HGNC:40797|Ensembl:ENSG00000249421 +103689911 CATIP-AS2 HGNC:HGNC:41079 +103689912 TBX2-AS1 HGNC:HGNC:50355|Ensembl:ENSG00000267280 +103689913 LINC00383 HGNC:HGNC:42710 +103689914 LOC103689914 - +103689915 DLEU1-AS1 HGNC:HGNC:50496|Ensembl:ENSG00000229323 +103689916 LOC103689916 - +103689917 LINC01337 HGNC:HGNC:50546|Ensembl:ENSG00000251221 +103689918 LINC01378 HGNC:HGNC:50645 +103695363 FOXG1-AS1 HGNC:HGNC:50663 +103695364 PKNOX2-AS1 HGNC:HGNC:50690|Ensembl:ENSG00000254880 +103695365 LINC01435 HGNC:HGNC:50753|Ensembl:ENSG00000229981 +103695366 LINC01461 HGNC:HGNC:50859 +103695431 LINC01048 HGNC:HGNC:49042|Ensembl:ENSG00000230390 +103695432 LINC01167 HGNC:HGNC:49536|Ensembl:ENSG00000224758 +103695433 LINC01322 HGNC:HGNC:50528 +103695434 LINC01396 HGNC:HGNC:50675|Ensembl:ENSG00000273396 +103695435 BBOX1-AS1 HGNC:HGNC:50700|Ensembl:ENSG00000254560 +103695436 LINC01269 HGNC:HGNC:50325|Ensembl:ENSG00000258689 +103724386 LINC00377 HGNC:HGNC:42703 +103724387 LINC01058 HGNC:HGNC:49061|Ensembl:ENSG00000225039 +103724388 LINC01068 HGNC:HGNC:49106|Ensembl:ENSG00000227676 +103724389 LINC01170 HGNC:HGNC:49542 +103724390 LINC01287 HGNC:HGNC:50351|Ensembl:ENSG00000234722 +103752554 MYCNUT MIM:615968|HGNC:HGNC:32684|Ensembl:ENSG00000223850 +103752555 SPATA17-AS1 HGNC:HGNC:41086|Ensembl:ENSG00000234070 +103752581 LINC01055 HGNC:HGNC:49049 +103752583 LINC01075 HGNC:HGNC:49118 +103752584 CCND2-AS1 HGNC:HGNC:49398|Ensembl:ENSG00000256164 +103752585 RORB-AS1 HGNC:HGNC:49803 +103752586 BIRC6-AS2 HGNC:HGNC:50490|Ensembl:ENSG00000279897 +103752587 FOXC2-AS1 HGNC:HGNC:50665|Ensembl:ENSG00000260944 +103752588 PACERR HGNC:HGNC:50552|Ensembl:ENSG00000273129 +103752589 TMEM92-AS1 HGNC:HGNC:50442|Ensembl:ENSG00000251179 +103753527 SCA37 MIM:615945|HGNC:HGNC:43726 +103753528 DUPXP11.22 MIM:300705 +103875461 SPDT MIM:184100 +103908604 LOC103908604 - +103908605 LOC103908605 - +104054148 LOC104054148 - +104169670 TMEM5-AS1 HGNC:HGNC:48910|Ensembl:ENSG00000255850 +104169671 LINC01036 HGNC:HGNC:49024 +104266956 LINC01044 HGNC:HGNC:49032|Ensembl:ENSG00000223626 +104266957 KBTBD11-OT1 HGNC:HGNC:49147|Ensembl:ENSG00000253696 +104266958 LINC01151 HGNC:HGNC:49471|Ensembl:ENSG00000253819 +104266959 LINC01195 HGNC:HGNC:49550|Ensembl:ENSG00000261075 +104266960 LINC01201 HGNC:HGNC:49632|Ensembl:ENSG00000228659 +104266961 LINC01221 HGNC:HGNC:49671|Ensembl:ENSG00000235492 +104266962 LINC01228 HGNC:HGNC:49681 +104266963 LINC01264 HGNC:HGNC:50282|Ensembl:ENSG00000229630 +104310350 LINC01327 HGNC:HGNC:50533|Ensembl:ENSG00000241669 +104310351 LINC01331 HGNC:HGNC:50538|Ensembl:ENSG00000248673 +104310353 LINC01399 HGNC:HGNC:50680|Ensembl:ENSG00000233080 +104326051 MAFA-AS1 HGNC:HGNC:51203|Ensembl:ENSG00000254338 +104326052 NRIR HGNC:HGNC:51269 +104326053 LINC00363 HGNC:HGNC:42684 +104326054 LINC00399 HGNC:HGNC:42728|Ensembl:ENSG00000229792 +104326055 APOA1-AS HGNC:HGNC:40079|Ensembl:ENSG00000235910 +104326056 ZNF511-PRAP1 HGNC:HGNC:38088 +104326057 GACAT1 HGNC:HGNC:48336|Ensembl:ENSG00000232991 +104326058 SMAD1-AS1 HGNC:HGNC:49379|Ensembl:ENSG00000250902 +104326187 EA8 MIM:616055 +104326188 LINC01202 HGNC:HGNC:49633 +104326189 LMO7DN-IT1 HGNC:HGNC:49790|Ensembl:ENSG00000223458 +104326190 LINC01309 HGNC:HGNC:50497|Ensembl:ENSG00000234551 +104326191 LINC01336 HGNC:HGNC:50543|Ensembl:ENSG00000250889 +104326192 PTPRJ-AS1 HGNC:HGNC:50634 +104326193 DLX2-AS1 HGNC:HGNC:50638|Ensembl:ENSG00000236651 +104355133 ABHD15-AS1 HGNC:HGNC:49685 +104355135 LINC00431 HGNC:HGNC:42766 +104355136 LINC01033 HGNC:HGNC:49019|Ensembl:ENSG00000249069 +104355137 LINC01072 HGNC:HGNC:49112|Ensembl:ENSG00000236076 +104355138 LINC01162 HGNC:HGNC:49528|Ensembl:ENSG00000232790 +104355139 LINC01397 HGNC:HGNC:50677|Ensembl:ENSG00000258673 +104355140 LINC00375 HGNC:HGNC:42699|Ensembl:ENSG00000226370 +104355141 LINC01143 HGNC:HGNC:49458|Ensembl:ENSG00000237751 +104355143 TXNDC12-AS1 HGNC:HGNC:30008|Ensembl:ENSG00000228369 +104355145 NCOA7-AS1 HGNC:HGNC:40954|Ensembl:ENSG00000232131 +104355146 LINC00396 HGNC:HGNC:42724|Ensembl:ENSG00000231428 +104355147 LINC00428 HGNC:HGNC:42763 +104355148 CYP4A22-AS1 HGNC:HGNC:43715 +104355149 LINC01039 HGNC:HGNC:49027 +104355150 LINC01054 HGNC:HGNC:49048 +104355152 LINC01090 HGNC:HGNC:49201|Ensembl:ENSG00000231689 +104355217 ERICD HGNC:HGNC:49404 +104355218 LINC01177 HGNC:HGNC:49549|Ensembl:ENSG00000261397 +104355219 LHX5-AS1 HGNC:HGNC:49570 +104355220 LINC01219 HGNC:HGNC:49653|Ensembl:ENSG00000232987 +104355285 LINC01256 HGNC:HGNC:49895|Ensembl:ENSG00000251398 +104355286 LINC01307 HGNC:HGNC:50494|Ensembl:ENSG00000231671 +104355287 LINC01317 HGNC:HGNC:50523|Ensembl:ENSG00000203386 +104355288 LINC01320 HGNC:HGNC:50526|Ensembl:ENSG00000228262 +104355289 LINC01324 HGNC:HGNC:50530|Ensembl:ENSG00000241767 +104355290 MIR217HG HGNC:HGNC:50537 +104355291 LINC01392 HGNC:HGNC:50668|Ensembl:ENSG00000233607 +104355292 LINC01525 HGNC:HGNC:51264|Ensembl:ENSG00000235202 +104355293 LINC00376 HGNC:HGNC:42701|Ensembl:ENSG00000227564 +104355294 LINC01386 HGNC:HGNC:50659|Ensembl:ENSG00000251324 +104355295 SGMS1-AS1 HGNC:HGNC:49683 +104355296 SCEL-AS1 HGNC:HGNC:39895|Ensembl:ENSG00000224347 +104355297 ABCA9-AS1 HGNC:HGNC:39983|Ensembl:ENSG00000231749 +104355426 LENG8-AS1 HGNC:HGNC:40705|Ensembl:ENSG00000226696 +104384744 TET2-AS1 HGNC:HGNC:41125 +104413890 ZBTB20-AS3 HGNC:HGNC:42422|Ensembl:ENSG00000239946 +104413891 SAPCD1-AS1 HGNC:HGNC:39824 +104413892 F10-AS1 HGNC:HGNC:40225 +104457406 MIR222HG HGNC:HGNC:49555 +104472519 STX18-IT1 HGNC:HGNC:41415|Ensembl:ENSG00000248221 +104472713 PCAT29 MIM:616273|HGNC:HGNC:50895|Ensembl:ENSG00000259641 +104472714 DISC1-IT1 HGNC:HGNC:41325|Ensembl:ENSG00000226758 +104472715 SNHG14 MIM:616259|HGNC:HGNC:37462 +104472716 WARS2-IT1 HGNC:HGNC:41393 +104472717 LINC01224 HGNC:HGNC:49676|Ensembl:ENSG00000269416 +104472718 LINC00508 HGNC:HGNC:43559 +104472848 IRAIN HGNC:HGNC:50365 +104502416 FOXP1-AS1 HGNC:HGNC:41942|Ensembl:ENSG00000244203 +104502417 MGAT3-AS1 HGNC:HGNC:51356|Ensembl:ENSG00000227188 +104533120 TRIM31-AS1 HGNC:HGNC:39761|Ensembl:ENSG00000231226 +104548970 UBE2V2P2 HGNC:HGNC:44887 +104548971 SALRNA1 HGNC:HGNC:49001 +104548972 SALRNA3 HGNC:HGNC:49002|Ensembl:ENSG00000281264 +104548973 SALRNA2 HGNC:HGNC:49003|Ensembl:ENSG00000280515 +104564224 LUNAR1 HGNC:HGNC:51199 +104564225 MHRT MIM:616096|HGNC:HGNC:51291 +104613533 LOC104613533 Ensembl:ENSG00000259170 +104644205 ENPP7P13 HGNC:HGNC:48696 +104797536 LINC01402 HGNC:HGNC:50685|Ensembl:ENSG00000228139 +104797537 GACAT3 MIM:616132|HGNC:HGNC:50847|Ensembl:ENSG00000236289 +104797538 KCNMB2-AS1 HGNC:HGNC:51409 +104798195 GS1-594A7.3 Ensembl:ENSG00000225833 +104909134 LINC02210-CRHR1 HGNC:HGNC:51483|Ensembl:ENSG00000263715|Vega:OTTHUMG00000178270 +104940698 DALIR HGNC:HGNC:51429 +104968399 LOC104968399 Ensembl:ENSG00000264235 +105031671 VVS MIM:609289 +105180377 CMTS MIM:616182 +105180390 SPDYE13P HGNC:HGNC:51509 +105180391 SPDYE15P HGNC:HGNC:51511 +105180392 HBB-3'HS1 - +105221694 BISPR HGNC:HGNC:51290|Ensembl:ENSG00000282851 +105259599 H19-ICR MIM:616186 +105259600 CXDUPQ26.3 MIM:300942 +105274304 LOC105274304 Ensembl:ENSG00000261335 +105274310 LOC105274310 - +105274375 TEMPS MIM:616222 +105317032 OI16 MIM:616229 +105369139 LOC105369139 - +105369140 LOC105369140 - +105369143 LOC105369143 - +105369146 LOC105369146 - +105369147 LOC105369147 - +105369149 LOC105369149 - +105369150 LOC105369150 - +105369151 LOC105369151 - +105369154 PKD1P6-NPIPP1 Ensembl:ENSG00000270580 +105369155 LOC105369155 - +105369161 LOC105369161 - +105369162 LOC105369162 - +105369163 LOC105369163 - +105369164 LOC105369164 - +105369165 LOC105369165 - +105369166 LOC105369166 - +105369167 LOC105369167 - +105369168 LOC105369168 - +105369170 LOC105369170 - +105369171 LOC105369171 - +105369176 LOC105369176 - +105369177 LOC105369177 - +105369180 LOC105369180 - +105369182 LOC105369182 - +105369183 LOC105369183 - +105369184 LOC105369184 - +105369187 LOC105369187 Ensembl:ENSG00000250748 +105369189 LOC105369189 - +105369190 LOC105369190 - +105369192 LOC105369192 Ensembl:ENSG00000246375 +105369194 LOC105369194 - +105369197 LOC105369197 - +105369199 LOC105369199 - +105369201 LOC105369201 - +105369202 LOC105369202 - +105369203 LOC105369203 Ensembl:ENSG00000258754 +105369205 LOC105369205 Ensembl:ENSG00000233098 +105369207 LOC105369207 - +105369209 LOC105369209 - +105369212 LOC105369212 - +105369213 LOC105369213 - +105369214 LOC105369214 - +105369216 LOC105369216 - +105369218 LOC105369218 - +105369219 LOC105369219 - +105369220 LOC105369220 - +105369222 LOC105369222 - +105369225 LOC105369225 - +105369226 LOC105369226 - +105369227 LOC105369227 - +105369228 LOC105369228 - +105369230 LOC105369230 - +105369231 LOC105369231 - +105369232 LOC105369232 - +105369233 LOC105369233 - +105369234 LOC105369234 - +105369235 LOC105369235 - +105369236 LOC105369236 - +105369239 LOC105369239 - +105369240 LOC105369240 - +105369241 LOC105369241 - +105369243 LOC105369243 - +105369244 LOC105369244 - +105369246 LOC105369246 - +105369247 LOC105369247 - +105369249 LOC105369249 - +105369250 LOC105369250 - +105369251 LOC105369251 - +105369252 LOC105369252 - +105369254 LOC105369254 - +105369255 LOC105369255 - +105369257 LOC105369257 - +105369260 LOC105369260 - +105369262 LOC105369262 - +105369265 LOC105369265 - +105369266 LOC105369266 - +105369268 LOC105369268 - +105369271 LOC105369271 - +105369273 LOC105369273 - +105369274 LOC105369274 - +105369275 LOC105369275 - +105369276 LOC105369276 - +105369277 LOC105369277 - +105369278 LOC105369278 - +105369279 LOC105369279 - +105369281 LOC105369281 - +105369283 LOC105369283 - +105369288 LOC105369288 - +105369289 LOC105369289 - +105369292 LOC105369292 - +105369293 LOC105369293 - +105369294 LOC105369294 - +105369295 LOC105369295 - +105369296 LOC105369296 - +105369297 LOC105369297 - +105369298 LOC105369298 - +105369299 LOC105369299 - +105369301 LOC105369301 - +105369302 LOC105369302 Ensembl:ENSG00000229425 +105369304 LOC105369304 - +105369305 LOC105369305 - +105369306 LOC105369306 - +105369308 LOC105369308 - +105369309 LOC105369309 - +105369310 LOC105369310 - +105369312 LOC105369312 - +105369313 LOC105369313 - +105369315 LOC105369315 - +105369316 SLC25A47P1 HGNC:HGNC:43860 +105369317 LOC105369317 - +105369318 LOC105369318 - +105369319 LOC105369319 - +105369320 LOC105369320 - +105369321 LOC105369321 - +105369322 LOC105369322 - +105369323 LOC105369323 - +105369325 LOC105369325 - +105369326 LOC105369326 - +105369329 LOC105369329 - +105369331 LOC105369331 - +105369332 LOC105369332 Ensembl:ENSG00000256690 +105369333 LOC105369333 - +105369334 LOC105369334 - +105369335 LOC105369335 - +105369339 LOC105369339 - +105369340 LOC105369340 Ensembl:ENSG00000256940 +105369341 LOC105369341 - +105369342 LOC105369342 - +105369343 MIR194-2HG HGNC:HGNC:51946 +105369344 LOC105369344 - +105369346 LOC105369346 - +105369347 LOC105369347 - +105369349 LOC105369349 - +105369350 LOC105369350 - +105369351 LOC105369351 - +105369352 LOC105369352 - +105369354 LOC105369354 - +105369355 LOC105369355 - +105369358 LOC105369358 - +105369359 LOC105369359 - +105369360 LOC105369360 - +105369361 LOC105369361 - +105369362 LOC105369362 - +105369363 LOC105369363 - +105369364 LOC105369364 Ensembl:ENSG00000250508 +105369366 LOC105369366 - +105369367 LOC105369367 - +105369368 LOC105369368 - +105369370 LOC105369370 - +105369371 LOC105369371 - +105369372 LOC105369372 - +105369373 LOC105369373 - +105369376 LOC105369376 - +105369377 LOC105369377 - +105369378 LOC105369378 - +105369379 LOC105369379 - +105369380 LOC105369380 - +105369381 LOC105369381 - +105369382 LOC105369382 - +105369383 LOC105369383 - +105369385 LOC105369385 - +105369386 LOC105369386 - +105369388 LOC105369388 - +105369389 LOC105369389 - +105369391 LOC105369391 - +105369392 LOC105369392 - +105369393 LOC105369393 - +105369395 LOC105369395 - +105369397 LOC105369397 - +105369399 LOC105369399 - +105369400 LOC105369400 - +105369401 LOC105369401 - +105369402 LOC105369402 - +105369403 LOC105369403 - +105369405 LOC105369405 - +105369406 LOC105369406 - +105369408 LOC105369408 - +105369409 LOC105369409 - +105369410 LOC105369410 - +105369413 LOC105369413 - +105369416 LOC105369416 - +105369420 LOC105369420 - +105369421 LOC105369421 - +105369422 LOC105369422 - +105369423 LOC105369423 Ensembl:ENSG00000255183 +105369425 LOC105369425 - +105369427 LOC105369427 - +105369428 LOC105369428 - +105369429 LOC105369429 - +105369431 LOC105369431 - +105369433 LOC105369433 - +105369434 LOC105369434 - +105369435 LOC105369435 - +105369436 LOC105369436 - +105369438 LOC105369438 Ensembl:ENSG00000255929 +105369439 LOC105369439 - +105369440 LOC105369440 - +105369441 LOC105369441 - +105369443 LOC105369443 Ensembl:ENSG00000256684 +105369444 LOC105369444 - +105369446 TOMM20P1 HGNC:HGNC:50518 +105369448 LOC105369448 - +105369449 LINC02553 HGNC:HGNC:53588 +105369450 LOC105369450 - +105369451 LOC105369451 - +105369452 LOC105369452 - +105369453 LOC105369453 - +105369454 LOC105369454 - +105369455 LOC105369455 - +105369456 LOC105369456 - +105369457 LOC105369457 - +105369458 LOC105369458 - +105369460 LOC105369460 - +105369461 LOC105369461 - +105369463 LOC105369463 - +105369464 LOC105369464 - +105369466 LOC105369466 - +105369467 LOC105369467 - +105369468 LOC105369468 - +105369469 LOC105369469 - +105369473 LOC105369473 Ensembl:ENSG00000254580 +105369474 LOC105369474 - +105369475 LOC105369475 - +105369477 LOC105369477 - +105369478 LOC105369478 - +105369479 LOC105369479 - +105369482 LOC105369482 - +105369483 LOC105369483 - +105369484 LOC105369484 - +105369486 LOC105369486 Ensembl:ENSG00000254416 +105369487 LOC105369487 - +105369488 LOC105369488 - +105369489 LOC105369489 - +105369490 LINC02550 HGNC:HGNC:53585 +105369491 LOC105369491 - +105369494 LOC105369494 - +105369496 LOC105369496 - +105369498 LOC105369498 - +105369499 LOC105369499 - +105369501 LOC105369501 - +105369504 LOC105369504 - +105369505 LOC105369505 - +105369506 LOC105369506 - +105369507 LOC105369507 Ensembl:ENSG00000256315 +105369509 LOC105369509 - +105369511 LOC105369511 - +105369512 LOC105369512 - +105369513 LOC105369513 - +105369515 LOC105369515 - +105369517 LOC105369517 - +105369519 LOC105369519 - +105369520 LOC105369520 Ensembl:ENSG00000254561 +105369525 LOC105369525 - +105369526 LOC105369526 - +105369527 LOC105369527 - +105369528 LOC105369528 - +105369529 LOC105369529 - +105369530 LOC105369530 - +105369531 LOC105369531 - +105369532 LOC105369532 - +105369533 LOC105369533 - +105369534 LOC105369534 - +105369535 LOC105369535 - +105369536 LOC105369536 - +105369539 LOC105369539 - +105369540 LOC105369540 - +105369541 LOC105369541 - +105369543 LOC105369543 - +105369544 LOC105369544 - +105369545 LOC105369545 - +105369546 LOC105369546 - +105369547 LOC105369547 - +105369549 LOC105369549 - +105369550 STT3A-AS1 HGNC:HGNC:44585|Ensembl:ENSG00000254671 +105369551 LOC105369551 - +105369552 LOC105369552 - +105369554 LOC105369554 - +105369557 HP11014 - +105369558 LOC105369558 - +105369559 LOC105369559 - +105369560 LOC105369560 - +105369561 LOC105369561 - +105369562 LOC105369562 - +105369563 LOC105369563 - +105369564 LINC02098 HGNC:HGNC:52950 +105369565 LOC105369565 - +105369566 LOC105369566 - +105369568 LOC105369568 - +105369571 LOC105369571 - +105369572 LOC105369572 - +105369574 LOC105369574 - +105369575 LOC105369575 - +105369576 LOC105369576 - +105369577 LOC105369577 - +105369578 LOC105369578 - +105369579 LOC105369579 - +105369580 LOC105369580 - +105369582 LOC105369582 - +105369583 LOC105369583 - +105369584 LOC105369584 - +105369586 LOC105369586 - +105369587 LOC105369587 - +105369588 LOC105369588 - +105369589 LOC105369589 - +105369591 LOC105369591 - +105369592 LOC105369592 - +105369593 LOC105369593 - +105369594 LOC105369594 - +105369595 LOC105369595 - +105369597 LINC02455 HGNC:HGNC:53388 +105369601 LOC105369601 - +105369602 LOC105369602 - +105369606 LOC105369606 - +105369607 LOC105369607 - +105369608 LOC105369608 - +105369609 LOC105369609 - +105369611 LOC105369611 - +105369612 LOC105369612 - +105369614 LOC105369614 - +105369616 LOC105369616 - +105369617 LOC105369617 - +105369618 LOC105369618 - +105369620 LOC105369620 - +105369621 LOC105369621 - +105369622 LOC105369622 - +105369623 LOC105369623 - +105369624 LOC105369624 - +105369625 LOC105369625 - +105369626 LOC105369626 - +105369628 LOC105369628 - +105369631 LOC105369631 - +105369632 LOC105369632 Ensembl:ENSG00000111671 +105369634 LOC105369634 - +105369635 MIR200CHG HGNC:HGNC:53161|Ensembl:ENSG00000257084 +105369639 LOC105369639 - +105369645 LOC105369645 - +105369647 LOC105369647 - +105369649 LOC105369649 - +105369650 LOC105369650 - +105369651 LOC105369651 - +105369652 LINC02390 HGNC:HGNC:53317 +105369653 LOC105369653 - +105369655 LOC105369655 - +105369656 LOC105369656 - +105369657 LOC105369657 - +105369658 LOC105369658 - +105369660 LOC105369660 - +105369663 LOC105369663 - +105369664 LOC105369664 - +105369665 LOC105369665 - +105369666 LOC105369666 - +105369667 LOC105369667 - +105369668 LOC105369668 - +105369669 LOC105369669 - +105369670 LOC105369670 - +105369672 LOC105369672 - +105369673 LOC105369673 - +105369676 LOC105369676 - +105369677 LOC105369677 - +105369678 LINC02378 HGNC:HGNC:53301 +105369682 LOC105369682 - +105369684 LINC02468 HGNC:HGNC:53406 +105369685 LOC105369685 - +105369686 LOC105369686 - +105369687 LOC105369687 - +105369688 LOC105369688 - +105369689 LOC105369689 - +105369690 LOC105369690 - +105369691 LOC105369691 - +105369692 LOC105369692 - +105369696 LOC105369696 - +105369697 LOC105369697 - +105369698 LOC105369698 - +105369699 LOC105369699 - +105369700 LOC105369700 - +105369701 LOC105369701 - +105369704 LOC105369704 - +105369705 LOC105369705 - +105369706 LOC105369706 - +105369709 LOC105369709 - +105369710 LOC105369710 - +105369711 LOC105369711 - +105369714 LOC105369714 - +105369715 LOC105369715 - +105369716 LOC105369716 - +105369717 LINC02386 HGNC:HGNC:53312 +105369718 LOC105369718 - +105369719 LOC105369719 - +105369720 LOC105369720 - +105369722 LOC105369722 - +105369723 LINC02422 HGNC:HGNC:53352|Ensembl:ENSG00000255760 +105369724 LOC105369724 - +105369725 LOC105369725 - +105369726 LOC105369726 - +105369728 LOC105369728 - +105369729 ZNF970P HGNC:HGNC:44511 +105369730 LINC02406 HGNC:HGNC:53334 +105369734 LINC02471 HGNC:HGNC:53410 +105369735 LOC105369735 - +105369736 LOC105369736 Ensembl:ENSG00000258167 +105369738 LINC02451 HGNC:HGNC:53383|Ensembl:ENSG00000257164 +105369739 LINC02450 HGNC:HGNC:53382|Ensembl:ENSG00000257114 +105369740 LINC02461 HGNC:HGNC:53398 +105369742 LOC105369742 - +105369743 LOC105369743 - +105369744 LOC105369744 - +105369745 LOC105369745 - +105369746 LOC105369746 - +105369747 LOC105369747 - +105369748 LOC105369748 Ensembl:ENSG00000257433 +105369750 LOC105369750 - +105369752 LOC105369752 - +105369753 LOC105369753 - +105369755 LOC105369755 - +105369756 LOC105369756 - +105369757 LOC105369757 - +105369758 DDN-AS1 HGNC:HGNC:53464|Ensembl:ENSG00000257913 +105369759 LOC105369759 - +105369760 LOC105369760 - +105369761 LOC105369761 - +105369762 LOC105369762 - +105369763 LOC105369763 - +105369764 LOC105369764 - +105369767 LOC105369767 - +105369768 LOC105369768 - +105369769 LOC105369769 - +105369771 LOC105369771 - +105369772 LOC105369772 - +105369774 LOC105369774 - +105369775 LOC105369775 - +105369776 SMUG1-AS1 HGNC:HGNC:53307 +105369777 LOC105369777 - +105369778 LOC105369778 - +105369779 LOC105369779 Ensembl:ENSG00000258056 +105369780 LOC105369780 - +105369781 LOC105369781 - +105369782 LOC105369782 - +105369783 LOC105369783 - +105369784 LOC105369784 - +105369785 LINC02403 HGNC:HGNC:53330|Ensembl:ENSG00000257541 +105369786 LOC105369786 - +105369787 LOC105369787 - +105369788 LOC105369788 - +105369789 LOC105369789 - +105369791 LOC105369791 - +105369792 LINC02448 HGNC:HGNC:53380 +105369793 LOC105369793 - +105369795 LOC105369795 - +105369797 LOC105369797 - +105369798 LOC105369798 - +105369801 LOC105369801 - +105369803 LOC105369803 - +105369804 LOC105369804 - +105369805 LOC105369805 - +105369806 LOC105369806 - +105369807 LINC02454 HGNC:HGNC:53387 +105369808 LOC105369808 - +105369809 LOC105369809 - +105369810 LINC02425 HGNC:HGNC:53356|Ensembl:ENSG00000256259 +105369811 LOC105369811 - +105369812 LOC105369812 - +105369813 LOC105369813 - +105369815 LINC02442 HGNC:HGNC:53374 +105369816 LOC105369816 - +105369818 LOC105369818 - +105369819 LOC105369819 - +105369820 LOC105369820 - +105369822 LINC02373 HGNC:HGNC:53295 +105369823 LOC105369823 - +105369826 LOC105369826 - +105369827 LOC105369827 - +105369828 LOC105369828 - +105369831 LOC105369831 - +105369832 LOC105369832 - +105369833 LOC105369833 - +105369838 LOC105369838 - +105369839 LOC105369839 - +105369840 LINC02445 HGNC:HGNC:53377 +105369841 LINC02394 HGNC:HGNC:53321 +105369842 LOC105369842 - +105369843 LOC105369843 - +105369844 LOC105369844 - +105369845 LOC105369845 - +105369846 LOC105369846 - +105369847 LOC105369847 - +105369848 LINC02407 HGNC:HGNC:53336|Ensembl:ENSG00000257219 +105369850 LOC105369850 - +105369851 LOC105369851 - +105369853 LOC105369853 - +105369854 LINC02464 HGNC:HGNC:53401 +105369855 LOC105369855 - +105369856 LOC105369856 - +105369859 LOC105369859 - +105369860 LINC02424 HGNC:HGNC:53354|Ensembl:ENSG00000258220 +105369863 LOC105369863 - +105369864 LOC105369864 - +105369865 PPP1R12A-AS1 HGNC:HGNC:51903 +105369866 LOC105369866 - +105369867 LOC105369867 - +105369869 LOC105369869 - +105369872 LOC105369872 - +105369873 LOC105369873 - +105369874 LOC105369874 - +105369875 LOC105369875 - +105369876 LOC105369876 - +105369877 LOC105369877 - +105369878 LOC105369878 - +105369879 LOC105369879 - +105369880 LOC105369880 - +105369881 LOC105369881 - +105369885 LOC105369885 - +105369886 LOC105369886 - +105369887 LOC105369887 - +105369889 LOC105369889 - +105369890 LOC105369890 - +105369891 LINC02399 HGNC:HGNC:53326|Ensembl:ENSG00000257725 +105369892 LOC105369892 - +105369893 LINC02392 HGNC:HGNC:53319 +105369895 LOC105369895 - +105369896 LOC105369896 - +105369897 LOC105369897 - +105369898 LOC105369898 - +105369900 LINC02404 HGNC:HGNC:53331 +105369901 LOC105369901 - +105369902 LOC105369902 - +105369903 LOC105369903 - +105369904 LOC105369904 - +105369905 LOC105369905 - +105369906 LINC02413 HGNC:HGNC:53342 +105369907 LOC105369907 - +105369908 LOC105369908 - +105369909 LOC105369909 - +105369911 LOC105369911 Ensembl:ENSG00000257283 +105369912 LOC105369912 - +105369913 LOC105369913 - +105369914 LOC105369914 - +105369915 LOC105369915 - +105369917 LOC105369917 - +105369919 LOC105369919 - +105369920 LINC02410 HGNC:HGNC:53339|Ensembl:ENSG00000258292 +105369921 LOC105369921 Ensembl:ENSG00000258343 +105369923 LOC105369923 - +105369924 LINC02452 HGNC:HGNC:53384 +105369925 LOC105369925 - +105369927 LOC105369927 - +105369928 LOC105369928 - +105369929 LINC02409 HGNC:HGNC:53338 +105369930 LOC105369930 - +105369932 LOC105369932 - +105369933 LOC105369933 - +105369935 LOC105369935 - +105369936 LOC105369936 - +105369937 LOC105369937 - +105369938 LOC105369938 - +105369942 LINC02456 HGNC:HGNC:53389 +105369944 LOC105369944 - +105369945 LOC105369945 - +105369946 LOC105369946 - +105369947 LOC105369947 - +105369948 LINC02385 HGNC:HGNC:53309 +105369949 LOC105369949 - +105369950 LOC105369950 - +105369952 LOC105369952 - +105369953 LOC105369953 - +105369954 KCCAT198 Ensembl:ENSG00000257642 +105369955 LOC105369955 - +105369956 LOC105369956 - +105369957 LOC105369957 - +105369958 LOC105369958 - +105369959 LOC105369959 - +105369960 LOC105369960 - +105369961 LOC105369961 - +105369963 LOC105369963 - +105369964 LOC105369964 - +105369965 LOC105369965 - +105369968 LOC105369968 - +105369969 LOC105369969 - +105369971 LOC105369971 Ensembl:ENSG00000259887 +105369972 LOC105369972 - +105369973 HNRNPA1P69 HGNC:HGNC:48799 +105369974 LOC105369974 - +105369975 LOC105369975 - +105369976 LOC105369976 - +105369978 LOC105369978 - +105369980 LOC105369980 Ensembl:ENSG00000258240 +105369981 LOC105369981 - +105369983 LOC105369983 - +105369984 LINC02356 HGNC:HGNC:53278|Ensembl:ENSG00000257595 +105369985 LOC105369985 - +105369987 IMMP1LP2 HGNC:HGNC:51132 +105369989 LOC105369989 - +105369990 LOC105369990 - +105369991 LOC105369991 - +105369993 LOC105369993 - +105369994 LOC105369994 - +105369995 LOC105369995 - +105369996 LINC02459 HGNC:HGNC:53395 +105369998 LOC105369998 - +105369999 LOC105369999 - +105370000 LOC105370000 - +105370002 LOC105370002 - +105370003 LOC105370003 - +105370004 LINC02463 HGNC:HGNC:53400 +105370005 LOC105370005 - +105370007 LOC105370007 - +105370008 LOC105370008 - +105370010 LOC105370010 - +105370011 LOC105370011 - +105370012 LOC105370012 - +105370013 LINC02460 HGNC:HGNC:53396 +105370014 LINC02423 HGNC:HGNC:53353|Ensembl:ENSG00000256750 +105370015 LINC02440 HGNC:HGNC:53372 +105370016 LINC02439 HGNC:HGNC:53371|Ensembl:ENSG00000255814 +105370017 LOC105370017 - +105370018 LOC105370018 - +105370019 LOC105370019 - +105370020 LOC105370020 - +105370021 LOC105370021 - +105370022 LOC105370022 - +105370024 LOC105370024 Ensembl:ENSG00000256884 +105370025 LOC105370025 - +105370026 LOC105370026 - +105370027 LOC105370027 Ensembl:ENSG00000248636 +105370029 LOC105370029 - +105370030 LOC105370030 - +105370031 LOC105370031 - +105370032 LOC105370032 - +105370033 LOC105370033 - +105370034 LOC105370034 - +105370035 LOC105370035 - +105370041 LOC105370041 - +105370042 LOC105370042 - +105370044 LOC105370044 - +105370045 LOC105370045 - +105370047 LOC105370047 - +105370050 LOC105370050 - +105370051 LOC105370051 - +105370052 LOC105370052 - +105370053 LOC105370053 - +105370054 LOC105370054 - +105370055 LOC105370055 - +105370056 LOC105370056 - +105370057 LOC105370057 - +105370058 LOC105370058 - +105370059 LINC02350 HGNC:HGNC:53272 +105370060 LOC105370060 - +105370061 LOC105370061 - +105370062 LOC105370062 - +105370063 LOC105370063 - +105370064 LOC105370064 - +105370065 LINC02376 HGNC:HGNC:53298 +105370066 LOC105370066 - +105370067 LOC105370067 - +105370068 LOC105370068 - +105370069 LOC105370069 - +105370070 LINC02441 HGNC:HGNC:53373|Ensembl:ENSG00000256643 +105370071 LOC105370071 - +105370073 LOC105370073 - +105370074 LOC105370074 - +105370076 LOC105370076 - +105370077 LOC105370077 - +105370078 LINC02419 HGNC:HGNC:53349 +105370079 LOC105370079 - +105370080 LOC105370080 - +105370082 LOC105370082 - +105370083 LOC105370083 - +105370084 LOC105370084 - +105370085 LINC02414 HGNC:HGNC:53343 +105370086 LOC105370086 - +105370087 LOC105370087 - +105370088 LOC105370088 - +105370090 LOC105370090 - +105370091 LOC105370091 - +105370092 LOC105370092 - +105370094 LOC105370094 - +105370099 LOC105370099 - +105370101 LOC105370101 - +105370102 LOC105370102 - +105370103 LOC105370103 - +105370104 LOC105370104 - +105370105 LOC105370105 Ensembl:ENSG00000235438 +105370108 LOC105370108 - +105370109 LOC105370109 - +105370111 LOC105370111 - +105370112 LOC105370112 - +105370113 LOC105370113 - +105370114 LOC105370114 - +105370115 LOC105370115 - +105370117 LOC105370117 - +105370118 LOC105370118 - +105370119 LOC105370119 - +105370120 LOC105370120 - +105370121 LOC105370121 - +105370122 LOC105370122 - +105370124 LOC105370124 - +105370125 LINC02340 HGNC:HGNC:53260 +105370126 LOC105370126 - +105370128 LOC105370128 - +105370129 LOC105370129 - +105370130 LOC105370130 - +105370132 LOC105370132 - +105370135 LOC105370135 - +105370139 LOC105370139 - +105370141 LINC00385 HGNC:HGNC:42713 +105370145 LOC105370145 - +105370148 LOC105370148 - +105370149 LOC105370149 - +105370150 LOC105370150 - +105370152 LOC105370152 - +105370154 LINC02344 HGNC:HGNC:53264 +105370156 LOC105370156 - +105370158 LINC02343 HGNC:HGNC:53263 +105370159 LOC105370159 - +105370161 LOC105370161 - +105370163 LOC105370163 - +105370165 LOC105370165 - +105370167 LOC105370167 - +105370168 LOC105370168 - +105370169 LOC105370169 - +105370170 LOC105370170 - +105370171 LOC105370171 - +105370173 LOC105370173 - +105370174 LOC105370174 - +105370175 LOC105370175 - +105370176 LOC105370176 - +105370177 LINC02341 HGNC:HGNC:53261|Ensembl:ENSG00000283554 +105370178 LOC105370178 - +105370179 LOC105370179 - +105370181 LOC105370181 - +105370182 LOC105370182 - +105370183 LINC00390 HGNC:HGNC:42718 +105370185 LOC105370185 - +105370186 LOC105370186 - +105370187 LOC105370187 - +105370188 LOC105370188 - +105370190 LOC105370190 - +105370191 LOC105370191 - +105370192 LOC105370192 - +105370194 LOC105370194 - +105370195 LOC105370195 - +105370196 LOC105370196 - +105370198 LOC105370198 - +105370199 LOC105370199 - +105370201 LOC105370201 - +105370202 LOC105370202 - +105370203 LOC105370203 - +105370204 LOC105370204 - +105370205 LOC105370205 - +105370207 LOC105370207 - +105370208 LINC00345 HGNC:HGNC:42503 +105370209 LOC105370209 - +105370210 LOC105370210 - +105370213 LOC105370213 - +105370214 LOC105370214 - +105370216 LOC105370216 - +105370217 LOC105370217 - +105370218 LOC105370218 - +105370219 LOC105370219 - +105370220 LOC105370220 - +105370221 LOC105370221 - +105370222 LOC105370222 - +105370223 LOC105370223 - +105370224 LOC105370224 - +105370227 LOC105370227 - +105370228 LOC105370228 - +105370230 LOC105370230 - +105370231 LOC105370231 - +105370232 LOC105370232 - +105370233 LOC105370233 - +105370234 LOC105370234 - +105370235 LOC105370235 - +105370236 LOC105370236 - +105370237 LOC105370237 - +105370238 LOC105370238 - +105370239 LOC105370239 - +105370240 LOC105370240 - +105370241 LOC105370241 - +105370242 LINC01052 HGNC:HGNC:49046 +105370243 LOC105370243 - +105370244 LOC105370244 - +105370245 LOC105370245 - +105370246 LOC105370246 - +105370247 LOC105370247 - +105370248 LOC105370248 - +105370249 LOC105370249 - +105370250 LOC105370250 - +105370251 LOC105370251 - +105370252 LOC105370252 - +105370253 LINC02342 HGNC:HGNC:53262 +105370254 LOC105370254 - +105370255 LOC105370255 - +105370256 LOC105370256 - +105370259 LOC105370259 - +105370260 LOC105370260 - +105370261 LOC105370261 - +105370262 LOC105370262 - +105370263 LOC105370263 - +105370264 LOC105370264 - +105370265 LOC105370265 - +105370266 LOC105370266 - +105370269 LOC105370269 - +105370271 LOC105370271 - +105370272 LOC105370272 - +105370273 LOC105370273 - +105370274 LOC105370274 - +105370275 LOC105370275 - +105370276 LOC105370276 - +105370278 LOC105370278 - +105370281 LOC105370281 - +105370282 LOC105370282 - +105370283 LOC105370283 - +105370284 LOC105370284 - +105370285 LOC105370285 - +105370286 LOC105370286 - +105370287 LOC105370287 - +105370289 LOC105370289 - +105370290 LOC105370290 - +105370291 LOC105370291 - +105370292 LOC105370292 - +105370295 LOC105370295 - +105370297 LOC105370297 - +105370298 LOC105370298 - +105370299 LOC105370299 - +105370300 LOC105370300 - +105370301 LOC105370301 - +105370302 LOC105370302 - +105370304 LOC105370304 - +105370306 LOC105370306 Ensembl:ENSG00000231019 +105370307 LOC105370307 - +105370308 LINC01040 HGNC:HGNC:49028|Ensembl:ENSG00000226037 +105370309 LINC02336 HGNC:HGNC:53256 +105370310 LOC105370310 - +105370311 LOC105370311 - +105370312 LOC105370312 - +105370313 LOC105370313 - +105370314 LOC105370314 - +105370315 LOC105370315 - +105370317 LOC105370317 - +105370321 LOC105370321 - +105370322 LOC105370322 - +105370324 LOC105370324 - +105370325 LOC105370325 - +105370327 LOC105370327 - +105370328 LOC105370328 - +105370330 LOC105370330 - +105370332 LOC105370332 - +105370333 LOC105370333 Ensembl:ENSG00000274605 +105370335 LOC105370335 - +105370337 LOC105370337 - +105370338 LOC105370338 - +105370339 LOC105370339 - +105370340 LOC105370340 - +105370342 LOC105370342 - +105370343 LOC105370343 - +105370344 LOC105370344 - +105370345 LOC105370345 - +105370346 LOC105370346 - +105370348 LOC105370348 - +105370349 LOC105370349 - +105370350 LOC105370350 - +105370353 LOC105370353 - +105370355 LOC105370355 - +105370356 LOC105370356 - +105370357 LINC00370 HGNC:HGNC:42692 +105370359 LOC105370359 - +105370360 LOC105370360 - +105370361 LOC105370361 - +105370362 LOC105370362 - +105370363 LOC105370363 - +105370364 LOC105370364 - +105370365 LOC105370365 - +105370366 LOC105370366 - +105370369 LINC02337 HGNC:HGNC:53257|Ensembl:ENSG00000215881 +105370370 LOC105370370 - +105370372 LOC105370372 - +105370373 LOC105370373 - +105370377 LOC105370377 - +105370378 LOC105370378 - +105370380 LOC105370380 - +105370384 LOC105370384 - +105370390 LOC105370390 - +105370392 LOC105370392 - +105370393 LOC105370393 - +105370397 LOC105370397 - +105370398 LOC105370398 - +105370399 LOC105370399 - +105370400 LINC02332 HGNC:HGNC:53252|Ensembl:ENSG00000259054 +105370401 LOC105370401 - +105370404 LOC105370404 - +105370406 LOC105370406 - +105370407 LOC105370407 - +105370408 LOC105370408 - +105370409 LOC105370409 - +105370410 LOC105370410 - +105370411 LOC105370411 - +105370412 LOC105370412 - +105370413 LOC105370413 - +105370414 LINC02286 HGNC:HGNC:53203 +105370415 LOC105370415 - +105370416 LOC105370416 - +105370418 LOC105370418 - +105370419 LOC105370419 - +105370420 LOC105370420 - +105370421 LOC105370421 - +105370422 LINC02300 HGNC:HGNC:53219 +105370423 LINC02281 HGNC:HGNC:53197 +105370424 LINC02282 HGNC:HGNC:53199|Ensembl:ENSG00000257056 +105370425 LINC02326 HGNC:HGNC:53246 +105370426 LOC105370426 - +105370428 LOC105370428 - +105370429 LOC105370429 - +105370430 LOC105370430 - +105370431 G2E3-AS1 HGNC:HGNC:53463 +105370432 LOC105370432 - +105370436 LOC105370436 - +105370437 LOC105370437 - +105370438 LOC105370438 - +105370439 LINC02313 HGNC:HGNC:53232 +105370440 LOC105370440 - +105370443 LOC105370443 - +105370444 LOC105370444 - +105370445 EGLN3-AS1 HGNC:HGNC:49077 +105370446 LOC105370446 - +105370447 LOC105370447 - +105370449 LOC105370449 - +105370450 LOC105370450 - +105370451 LOC105370451 - +105370452 LOC105370452 - +105370453 LOC105370453 - +105370455 LOC105370455 - +105370456 LOC105370456 - +105370457 LOC105370457 - +105370458 SEC23A-AS1 HGNC:HGNC:53213|Ensembl:ENSG00000258651 +105370459 LOC105370459 - +105370460 LOC105370460 - +105370461 LOC105370461 - +105370462 LOC105370462 - +105370463 LOC105370463 - +105370464 LOC105370464 - +105370465 LOC105370465 - +105370466 LOC105370466 - +105370467 LOC105370467 - +105370469 LOC105370469 - +105370470 LOC105370470 - +105370471 LINC02307 HGNC:HGNC:53226 +105370472 LOC105370472 - +105370473 LOC105370473 Ensembl:ENSG00000258747 +105370474 LOC105370474 - +105370475 LOC105370475 - +105370476 LOC105370476 - +105370478 LOC105370478 - +105370479 LINC02303 HGNC:HGNC:53222 +105370480 LOC105370480 - +105370481 LOC105370481 - +105370482 LOC105370482 - +105370485 LOC105370485 - +105370486 LOC105370486 - +105370487 LOC105370487 - +105370489 LOC105370489 Ensembl:ENSG00000258843 +105370491 LOC105370491 - +105370492 LOC105370492 - +105370495 LOC105370495 - +105370496 LINC02310 HGNC:HGNC:53229 +105370497 LOC105370497 - +105370498 LINC02319 HGNC:HGNC:53238 +105370500 LOC105370500 - +105370502 LOC105370502 - +105370503 LINC02331 HGNC:HGNC:53251 +105370504 LOC105370504 - +105370505 LOC105370505 - +105370507 LOC105370507 - +105370508 LOC105370508 - +105370509 LOC105370509 - +105370511 LOC105370511 - +105370512 LOC105370512 - +105370513 LOC105370513 - +105370514 LOC105370514 - +105370515 LOC105370515 - +105370516 LOC105370516 - +105370518 LOC105370518 - +105370519 LOC105370519 - +105370522 LOC105370522 - +105370524 LOC105370524 - +105370525 LOC105370525 - +105370526 LOC105370526 - +105370527 LOC105370527 - +105370528 LOC105370528 - +105370529 LOC105370529 - +105370530 LOC105370530 - +105370531 LOC105370531 - +105370532 LOC105370532 - +105370534 LOC105370534 - +105370537 LOC105370537 - +105370538 LOC105370538 - +105370539 LOC105370539 - +105370540 LINC02290 HGNC:HGNC:53206 +105370542 LOC105370542 - +105370543 LOC105370543 - +105370546 LOC105370546 - +105370547 LOC105370547 - +105370549 LOC105370549 - +105370550 LOC105370550 - +105370552 LOC105370552 - +105370555 LOC105370555 - +105370556 LOC105370556 - +105370557 LOC105370557 - +105370558 LOC105370558 - +105370559 LOC105370559 - +105370560 LOC105370560 - +105370563 LOC105370563 - +105370564 LOC105370564 - +105370567 LOC105370567 - +105370569 LOC105370569 - +105370571 LOC105370571 - +105370572 LOC105370572 - +105370573 LOC105370573 - +105370575 LOC105370575 - +105370576 LOC105370576 - +105370577 LOC105370577 - +105370578 LINC01629 HGNC:HGNC:52260|Ensembl:ENSG00000258602 +105370579 LOC105370579 - +105370581 LOC105370581 - +105370582 LOC105370582 - +105370583 LOC105370583 - +105370585 LOC105370585 - +105370586 LOC105370586 Ensembl:ENSG00000258419 +105370587 LOC105370587 - +105370588 LOC105370588 - +105370589 LOC105370589 - +105370590 LOC105370590 - +105370591 LOC105370591 - +105370593 LOC105370593 - +105370594 LOC105370594 - +105370596 LOC105370596 - +105370598 LOC105370598 - +105370599 LOC105370599 - +105370600 LOC105370600 - +105370601 LOC105370601 - +105370603 LOC105370603 - +105370604 LOC105370604 - +105370605 LINC02329 HGNC:HGNC:53249|Ensembl:ENSG00000258814 +105370607 LINC02309 HGNC:HGNC:53228 +105370608 LOC105370608 - +105370610 LINC02296 HGNC:HGNC:53212 +105370611 LINC02330 HGNC:HGNC:53250 +105370612 LOC105370612 - +105370613 LOC105370613 - +105370614 LOC105370614 - +105370615 LOC105370615 - +105370616 LOC105370616 Ensembl:ENSG00000258792 +105370617 LOC105370617 - +105370618 LOC105370618 - +105370619 LOC105370619 - +105370620 LOC105370620 - +105370622 LOC105370622 Ensembl:ENSG00000258716 +105370623 LINC02321 HGNC:HGNC:53240|Ensembl:ENSG00000258884 +105370624 LOC105370624 - +105370625 LOC105370625 - +105370627 LOC105370627 - +105370629 LOC105370629 - +105370631 LOC105370631 - +105370634 LOC105370634 - +105370635 LOC105370635 - +105370637 LOC105370637 - +105370638 LOC105370638 - +105370639 LOC105370639 - +105370640 LOC105370640 - +105370641 LOC105370641 - +105370643 LOC105370643 - +105370644 LOC105370644 - +105370645 LOC105370645 - +105370646 LINC02299 HGNC:HGNC:53218|Ensembl:ENSG00000258979 +105370647 LOC105370647 - +105370648 LINC02304 HGNC:HGNC:53223|Ensembl:ENSG00000259110 +105370650 LOC105370650 - +105370651 LOC105370651 - +105370652 LINC02295 HGNC:HGNC:53211 +105370653 LOC105370653 - +105370654 LOC105370654 - +105370655 LOC105370655 - +105370656 LOC105370656 - +105370657 LOC105370657 - +105370658 LOC105370658 - +105370659 LOC105370659 - +105370660 LOC105370660 - +105370661 LOC105370661 - +105370664 LOC105370664 - +105370667 LOC105370667 - +105370668 LOC105370668 - +105370669 LOC105370669 - +105370670 LOC105370670 - +105370671 LOC105370671 - +105370672 LOC105370672 - +105370673 LOC105370673 - +105370674 LOC105370674 - +105370675 LOC105370675 - +105370676 LINC02320 HGNC:HGNC:53239 +105370677 LOC105370677 - +105370679 LOC105370679 - +105370680 LOC105370680 - +105370681 LINC02323 HGNC:HGNC:53242|Ensembl:ENSG00000259230 +105370683 LINC00677 HGNC:HGNC:20121 +105370685 LOC105370685 - +105370686 LOC105370686 - +105370687 LOC105370687 - +105370688 LOC105370688 - +105370689 LOC105370689 - +105370690 LOC105370690 - +105370691 LOC105370691 - +105370692 LOC105370692 - +105370693 LOC105370693 - +105370694 LOC105370694 - +105370697 LOC105370697 - +105370698 LOC105370698 - +105370700 LOC105370700 - +105370703 LOC105370703 - +105370705 LOC105370705 - +105370706 LOC105370706 - +105370707 LOC105370707 - +105370708 LOC105370708 - +105370709 LOC105370709 - +105370710 LOC105370710 - +105370711 LOC105370711 - +105370712 LOC105370712 - +105370713 LOC105370713 - +105370714 LOC105370714 - +105370715 LOC105370715 - +105370720 LOC105370720 - +105370721 LOC105370721 - +105370722 LOC105370722 - +105370724 LOC105370724 - +105370725 LOC105370725 - +105370726 LOC105370726 - +105370728 LOC105370728 - +105370729 LOC105370729 - +105370730 LOC105370730 - +105370731 PWRN4 HGNC:HGNC:49130 +105370732 LOC105370732 - +105370733 LOC105370733 - +105370734 LOC105370734 - +105370737 LINC02250 HGNC:HGNC:53148 +105370738 LOC105370738 - +105370739 LOC105370739 - +105370740 LOC105370740 - +105370741 LOC105370741 - +105370743 LOC105370743 - +105370746 LOC105370746 - +105370747 LOC105370747 - +105370748 LOC105370748 - +105370750 LOC105370750 - +105370751 LOC105370751 - +105370752 LOC105370752 - +105370753 LOC105370753 - +105370754 LOC105370754 - +105370755 LOC105370755 - +105370756 LOC105370756 - +105370757 LOC105370757 Ensembl:ENSG00000241818 +105370759 LOC105370759 - +105370761 LOC105370761 - +105370762 LINC02252 HGNC:HGNC:53150 +105370763 LOC105370763 - +105370764 LOC105370764 - +105370765 LOC105370765 - +105370766 LOC105370766 - +105370767 LOC105370767 - +105370768 LOC105370768 - +105370769 LOC105370769 - +105370770 LOC105370770 - +105370772 LOC105370772 - +105370773 LOC105370773 - +105370774 LOC105370774 - +105370775 LOC105370775 - +105370776 LOC105370776 - +105370777 LOC105370777 - +105370780 LOC105370780 - +105370781 LOC105370781 - +105370783 LOC105370783 - +105370784 LOC105370784 - +105370785 LOC105370785 - +105370786 LOC105370786 - +105370787 LOC105370787 - +105370788 LOC105370788 - +105370789 LOC105370789 - +105370790 LOC105370790 - +105370791 LOC105370791 - +105370792 LOC105370792 - +105370793 LOC105370793 - +105370794 LOC105370794 - +105370795 LOC105370795 - +105370796 LOC105370796 - +105370798 LOC105370798 - +105370802 LOC105370802 Ensembl:ENSG00000259200 +105370803 LOC105370803 - +105370804 LOC105370804 - +105370805 LOC105370805 - +105370807 LOC105370807 - +105370809 LOC105370809 Ensembl:ENSG00000259705 +105370811 LOC105370811 - +105370816 LOC105370816 - +105370819 LOC105370819 - +105370820 LOC105370820 - +105370821 LOC105370821 - +105370822 LINC02490 HGNC:HGNC:53471 +105370823 LOC105370823 - +105370824 LOC105370824 - +105370826 LOC105370826 - +105370827 LOC105370827 - +105370829 LOC105370829 Ensembl:ENSG00000260937 +105370831 LOC105370831 - +105370832 LOC105370832 - +105370833 LOC105370833 - +105370834 LOC105370834 - +105370838 LOC105370838 - +105370839 LOC105370839 - +105370840 LOC105370840 - +105370841 LOC105370841 - +105370842 LOC105370842 - +105370844 LOC105370844 - +105370846 LOC105370846 - +105370847 LOC105370847 - +105370848 LOC105370848 - +105370849 LOC105370849 - +105370850 LOC105370850 - +105370851 LOC105370851 - +105370852 LOC105370852 - +105370854 LOC105370854 - +105370855 LOC105370855 - +105370858 LOC105370858 - +105370861 LOC105370861 - +105370862 LOC105370862 - +105370866 LOC105370866 - +105370867 LOC105370867 - +105370868 LOC105370868 Ensembl:ENSG00000261318 +105370869 LOC105370869 - +105370870 LOC105370870 - +105370871 LOC105370871 - +105370873 LOC105370873 - +105370876 LOC105370876 - +105370877 LOC105370877 - +105370878 LOC105370878 - +105370879 LOC105370879 - +105370880 LINC02205 HGNC:HGNC:53071 +105370884 LOC105370884 - +105370886 LOC105370886 - +105370887 LOC105370887 - +105370888 TMEM202-AS1 HGNC:HGNC:53265|Ensembl:ENSG00000261423 +105370890 LOC105370890 - +105370891 LOC105370891 - +105370892 LOC105370892 - +105370893 LOC105370893 - +105370894 LINC02255 HGNC:HGNC:53153 +105370897 LOC105370897 - +105370902 LOC105370902 - +105370904 LOC105370904 - +105370905 LOC105370905 - +105370906 LOC105370906 Ensembl:ENSG00000259420 +105370910 LOC105370910 - +105370911 LOC105370911 - +105370912 LOC105370912 - +105370913 LOC105370913 - +105370914 LOC105370914 - +105370917 LOC105370917 - +105370918 LOC105370918 - +105370919 LOC105370919 - +105370921 LOC105370921 - +105370922 LOC105370922 - +105370923 LOC105370923 - +105370924 LOC105370924 - +105370926 LOC105370926 - +105370928 LOC105370928 - +105370932 LOC105370932 - +105370933 LOC105370933 - +105370934 LOC105370934 - +105370935 LOC105370935 - +105370936 LOC105370936 - +105370939 LOC105370939 - +105370940 LOC105370940 - +105370941 LOC105370941 Ensembl:ENSG00000261136 +105370943 LOC105370943 - +105370946 LOC105370946 - +105370947 LOC105370947 - +105370948 LOC105370948 - +105370952 LOC105370952 - +105370953 LOC105370953 - +105370954 LOC105370954 Ensembl:ENSG00000259636 +105370955 LOC105370955 - +105370956 LOC105370956 - +105370957 LOC105370957 - +105370958 LOC105370958 - +105370959 LOC105370959 - +105370960 LOC105370960 - +105370961 LOC105370961 - +105370963 LOC105370963 - +105370964 LOC105370964 - +105370965 LOC105370965 - +105370966 LOC105370966 - +105370969 LOC105370969 - +105370970 LOC105370970 - +105370972 LOC105370972 - +105370973 LOC105370973 Ensembl:ENSG00000258765 +105370974 LOC105370974 - +105370975 LOC105370975 - +105370978 LOC105370978 - +105370979 LOC105370979 - +105370980 LOC105370980 - +105370981 LOC105370981 - +105370982 LOC105370982 - +105370984 LOC105370984 - +105370985 LOC105370985 - +105370986 LOC105370986 - +105370987 LOC105370987 - +105370988 LOC105370988 - +105370989 LOC105370989 - +105370990 LOC105370990 - +105370991 LOC105370991 - +105370992 LOC105370992 - +105370993 LOC105370993 - +105370994 LOC105370994 - +105370995 LOC105370995 - +105370997 LOC105370997 - +105370998 LOC105370998 - +105371001 LOC105371001 - +105371002 LOC105371002 - +105371004 LOC105371004 - +105371005 LOC105371005 - +105371006 LOC105371006 - +105371007 LOC105371007 - +105371008 LINC02251 HGNC:HGNC:53149 +105371009 LOC105371009 - +105371010 LOC105371010 - +105371011 LINC02351 HGNC:HGNC:53273 +105371013 LOC105371013 - +105371016 LOC105371016 - +105371017 LOC105371017 - +105371018 LOC105371018 - +105371019 LOC105371019 - +105371020 LOC105371020 - +105371021 LOC105371021 - +105371022 LOC105371022 Ensembl:ENSG00000259219 +105371024 LOC105371024 - +105371025 LOC105371025 - +105371026 LOC105371026 - +105371027 PCSK6-AS1 HGNC:HGNC:51448|Ensembl:ENSG00000259764 +105371028 LOC105371028 - +105371030 LOC105371030 - +105371031 LOC105371031 - +105371032 LOC105371032 - +105371036 LOC105371036 - +105371038 LOC105371038 - +105371042 LOC105371042 - +105371044 LOC105371044 - +105371045 LOC105371045 Ensembl:ENSG00000284395 +105371046 LOC105371046 Ensembl:ENSG00000260989 +105371047 LOC105371047 - +105371048 LINC02124 HGNC:HGNC:52981 +105371049 LOC105371049 Ensembl:ENSG00000259933 +105371050 LOC105371050 Ensembl:ENSG00000260874 +105371053 LOC105371053 - +105371055 LOC105371055 - +105371056 LOC105371056 - +105371058 LOC105371058 - +105371059 LOC105371059 - +105371060 LOC105371060 - +105371062 LOC105371062 - +105371063 LOC105371063 - +105371064 LOC105371064 - +105371065 LOC105371065 - +105371066 LINC02164 HGNC:HGNC:53025 +105371067 LOC105371067 - +105371068 LOC105371068 - +105371069 LOC105371069 - +105371070 LOC105371070 - +105371071 LINC02152 HGNC:HGNC:53014 +105371072 LOC105371072 - +105371074 LOC105371074 - +105371075 LOC105371075 - +105371076 LOC105371076 - +105371077 LOC105371077 - +105371078 LOC105371078 - +105371079 LOC105371079 Ensembl:ENSG00000263279 +105371080 LOC105371080 - +105371081 LOC105371081 - +105371082 LOC105371082 - +105371083 LOC105371083 Ensembl:ENSG00000263080 +105371084 LOC105371084 Ensembl:ENSG00000263307 +105371085 LOC105371085 - +105371086 LOC105371086 - +105371087 LOC105371087 - +105371088 LOC105371088 - +105371089 LOC105371089 - +105371090 LOC105371090 - +105371091 LOC105371091 - +105371092 LOC105371092 - +105371093 LOC105371093 - +105371094 LOC105371094 - +105371095 LOC105371095 - +105371096 LOC105371096 - +105371097 LOC105371097 - +105371098 LOC105371098 - +105371099 LOC105371099 - +105371100 LOC105371100 - +105371102 LOC105371102 - +105371103 LOC105371103 - +105371105 LOC105371105 - +105371106 LOC105371106 - +105371108 LOC105371108 - +105371109 LOC105371109 - +105371110 LOC105371110 - +105371113 LOC105371113 - +105371114 LOC105371114 - +105371115 LOC105371115 - +105371116 LOC105371116 - +105371117 LOC105371117 - +105371119 LOC105371119 - +105371120 LOC105371120 - +105371121 LOC105371121 - +105371122 LOC105371122 - +105371123 LOC105371123 - +105371124 LOC105371124 - +105371125 LOC105371125 - +105371126 LOC105371126 - +105371128 LOC105371128 - +105371129 LOC105371129 - +105371130 MFSD13B HGNC:HGNC:52163 +105371131 LOC105371131 - +105371132 LOC105371132 - +105371134 LOC105371134 - +105371136 LOC105371136 - +105371137 LOC105371137 - +105371139 LOC105371139 - +105371141 LOC105371141 - +105371142 LINC2194 HGNC:HGNC:53057 +105371143 LOC105371143 - +105371145 LOC105371145 - +105371146 LINC02191 HGNC:HGNC:53053 +105371147 LOC105371147 - +105371149 LOC105371149 - +105371150 LOC105371150 - +105371152 LINC02195 HGNC:HGNC:53058 +105371153 LOC105371153 - +105371154 LOC105371154 - +105371155 LOC105371155 - +105371156 LINC02129 HGNC:HGNC:52988|Ensembl:ENSG00000261045 +105371157 LOC105371157 - +105371159 LOC105371159 - +105371161 LOC105371161 - +105371167 LOC105371167 - +105371168 LOC105371168 - +105371170 LOC105371170 - +105371172 LOC105371172 - +105371173 LINC02190 HGNC:HGNC:53052 +105371174 LOC105371174 - +105371175 LOC105371175 - +105371176 LOC105371176 - +105371177 LOC105371177 - +105371181 LOC105371181 - +105371184 LOC105371184 Ensembl:ENSG00000260394 +105371186 LOC105371186 - +105371187 LOC105371187 - +105371189 LOC105371189 - +105371191 LOC105371191 - +105371194 LOC105371194 - +105371195 LOC105371195 - +105371196 LOC105371196 - +105371197 LOC105371197 - +105371198 LOC105371198 - +105371199 LOC105371199 - +105371200 LOC105371200 - +105371201 LOC105371201 - +105371203 LOC105371203 - +105371204 LOC105371204 - +105371206 LOC105371206 - +105371207 LOC105371207 - +105371209 LOC105371209 - +105371211 LOC105371211 - +105371214 LOC105371214 - +105371215 LOC105371215 - +105371216 LOC105371216 - +105371217 LOC105371217 - +105371219 LOC105371219 - +105371222 LOC105371222 - +105371223 LOC105371223 - +105371224 LOC105371224 - +105371225 LOC105371225 - +105371226 LINC01731 HGNC:HGNC:52519 +105371227 LOC105371227 - +105371228 LOC105371228 - +105371229 LOC105371229 - +105371230 LOC105371230 - +105371231 LOC105371231 - +105371233 LOC105371233 - +105371235 LOC105371235 - +105371236 LOC105371236 - +105371237 LOC105371237 - +105371238 LINC02134 HGNC:HGNC:52994 +105371239 LOC105371239 - +105371240 LOC105371240 - +105371241 LOC105371241 - +105371242 LOC105371242 Ensembl:ENSG00000270339 +105371243 LOC105371243 - +105371244 LOC105371244 - +105371245 LOC105371245 - +105371248 LINC02178 HGNC:HGNC:53040 +105371249 LOC105371249 - +105371251 LOC105371251 - +105371252 LINC02168 HGNC:HGNC:53030|Ensembl:ENSG00000261703 +105371253 LOC105371253 - +105371254 LOC105371254 - +105371256 LOC105371256 - +105371257 LOC105371257 - +105371259 LOC105371259 - +105371260 LIX1L-AS1 HGNC:HGNC:41210|Ensembl:ENSG00000234222 +105371261 LOC105371261 - +105371262 LOC105371262 - +105371264 LOC105371264 - +105371265 LOC105371265 - +105371267 LOC105371267 Ensembl:ENSG00000277639 +105371268 LOC105371268 - +105371269 LOC105371269 - +105371271 LOC105371271 - +105371272 LOC105371272 - +105371273 LINC02183 HGNC:HGNC:53045 +105371274 LOC105371274 - +105371275 LOC105371275 - +105371276 LOC105371276 - +105371277 LOC105371277 - +105371278 LOC105371278 - +105371279 LOC105371279 - +105371280 LOC105371280 - +105371281 LOC105371281 - +105371283 LOC105371283 - +105371286 LOC105371286 Ensembl:ENSG00000261302 +105371287 LOC105371287 - +105371288 LOC105371288 - +105371289 LOC105371289 - +105371291 LOC105371291 - +105371293 LOC105371293 - +105371295 LINC02137 HGNC:HGNC:52997 +105371296 LOC105371296 - +105371298 LOC105371298 - +105371299 LOC105371299 - +105371300 LOC105371300 - +105371301 LOC105371301 - +105371302 LOC105371302 - +105371303 LOC105371303 - +105371305 LOC105371305 - +105371306 LOC105371306 - +105371307 LOC105371307 - +105371308 LOC105371308 - +105371309 LOC105371309 - +105371310 LOC105371310 - +105371311 LOC105371311 - +105371312 LOC105371312 - +105371313 LOC105371313 - +105371314 LOC105371314 - +105371316 LOC105371316 - +105371317 LOC105371317 - +105371318 LOC105371318 - +105371321 LOC105371321 - +105371325 LOC105371325 - +105371328 LOC105371328 - +105371329 LOC105371329 - +105371332 LOC105371332 - +105371333 LINC02136 HGNC:HGNC:52995|Ensembl:ENSG00000261348 +105371334 LOC105371334 - +105371335 LOC105371335 Ensembl:ENSG00000260520 +105371336 LOC105371336 - +105371337 LOC105371337 - +105371341 LOC105371341 - +105371342 LOC105371342 - +105371343 LOC105371343 - +105371344 LOC105371344 - +105371345 LOC105371345 - +105371346 CPHXL HGNC:HGNC:51815 +105371347 LOC105371347 - +105371348 LOC105371348 Ensembl:ENSG00000166848|Vega:OTTHUMG00000177136 +105371349 LOC105371349 - +105371350 LINC02131 HGNC:HGNC:52991|Ensembl:ENSG00000261154 +105371351 LOC105371351 - +105371352 LOC105371352 - +105371354 LOC105371354 - +105371356 LOC105371356 - +105371357 LOC105371357 - +105371358 LOC105371358 - +105371359 LOC105371359 - +105371360 LOC105371360 - +105371361 LOC105371361 - +105371362 LOC105371362 - +105371363 LOC105371363 - +105371366 LOC105371366 - +105371368 LOC105371368 - +105371370 LOC105371370 - +105371371 LOC105371371 - +105371372 LOC105371372 - +105371374 ATP2C2-AS1 HGNC:HGNC:53167 +105371376 LOC105371376 - +105371378 LOC105371378 - +105371379 LINC02176 HGNC:HGNC:53038 +105371380 LOC105371380 - +105371381 LOC105371381 - +105371382 LOC105371382 - +105371388 LOC105371388 - +105371389 LOC105371389 - +105371392 LOC105371392 - +105371393 LOC105371393 - +105371394 LOC105371394 - +105371397 LOC105371397 Ensembl:ENSG00000104731 +105371399 LOC105371399 - +105371400 LOC105371400 - +105371401 LOC105371401 - +105371403 LOC105371403 - +105371406 LOC105371406 - +105371409 LOC105371409 - +105371411 LOC105371411 - +105371412 LOC105371412 - +105371413 LOC105371413 - +105371414 LOC105371414 - +105371416 LINC02166 HGNC:HGNC:53027|Ensembl:ENSG00000260259 +105371419 LOC105371419 - +105371423 LINC02193 HGNC:HGNC:53055 +105371425 LOC105371425 - +105371427 LOC105371427 - +105371430 LOC105371430 Ensembl:ENSG00000241525 +105371432 LOC105371432 - +105371433 LOC105371433 - +105371434 LOC105371434 - +105371436 LOC105371436 - +105371438 LOC105371438 - +105371441 LOC105371441 - +105371442 LOC105371442 - +105371444 LOC105371444 - +105371445 LOC105371445 - +105371446 LOC105371446 - +105371448 LOC105371448 - +105371449 LOC105371449 - +105371450 LOC105371450 - +105371452 LOC105371452 - +105371453 LOC105371453 - +105371455 LOC105371455 - +105371456 LOC105371456 - +105371457 LOC105371457 - +105371458 LOC105371458 Ensembl:ENSG00000236957 +105371459 LOC105371459 - +105371460 LOC105371460 - +105371461 LOC105371461 - +105371462 LOC105371462 - +105371464 LOC105371464 - +105371466 LOC105371466 - +105371467 LOC105371467 - +105371468 LOC105371468 - +105371470 LOC105371470 - +105371471 LOC105371471 - +105371472 LOC105371472 - +105371473 LOC105371473 - +105371475 LOC105371475 - +105371479 LOC105371479 - +105371480 LOC105371480 - +105371481 LOC105371481 - +105371483 LOC105371483 - +105371485 LOC105371485 Ensembl:ENSG00000228133 +105371486 LOC105371486 - +105371490 LOC105371490 - +105371492 LOC105371492 - +105371493 LOC105371493 - +105371496 LINC01975 HGNC:HGNC:52802 +105371497 LOC105371497 - +105371498 LOC105371498 - +105371499 LOC105371499 - +105371501 LOC105371501 - +105371502 LOC105371502 - +105371505 LOC105371505 - +105371506 LOC105371506 Ensembl:ENSG00000262099 +105371507 LOC105371507 - +105371508 LOC105371508 Ensembl:ENSG00000262231 +105371509 LOC105371509 - +105371510 LOC105371510 - +105371512 LOC105371512 - +105371516 LOC105371516 - +105371517 LOC105371517 - +105371520 LOC105371520 - +105371521 LOC105371521 - +105371525 LOC105371525 - +105371526 LOC105371526 - +105371529 LOC105371529 - +105371530 LOC105371530 - +105371531 LOC105371531 - +105371532 LOC105371532 - +105371533 LOC105371533 - +105371536 LOC105371536 - +105371539 LOC105371539 - +105371540 LOC105371540 - +105371541 LINC02093 HGNC:HGNC:52944 +105371543 LOC105371543 - +105371544 LOC105371544 - +105371545 LOC105371545 - +105371547 LOC105371547 - +105371551 LOC105371551 - +105371552 LOC105371552 - +105371553 LOC105371553 - +105371554 LOC105371554 - +105371557 LOC105371557 - +105371559 LOC105371559 - +105371560 LOC105371560 - +105371561 LOC105371561 - +105371562 LINC02090 HGNC:HGNC:52941 +105371564 SMCR2 HGNC:HGNC:17914|Ensembl:ENSG00000223979 +105371565 LOC105371565 - +105371566 LOC105371566 - +105371567 LOC105371567 - +105371568 LOC105371568 - +105371569 LOC105371569 - +105371570 LOC105371570 - +105371572 LOC105371572 - +105371573 LOC105371573 - +105371574 LOC105371574 - +105371578 LOC105371578 - +105371579 LOC105371579 - +105371580 LOC105371580 - +105371581 LOC105371581 - +105371582 LINC02088 HGNC:HGNC:52939 +105371583 LOC105371583 - +105371586 LOC105371586 - +105371589 LOC105371589 - +105371590 LINC01675 HGNC:HGNC:52463 +105371591 LOC105371591 - +105371592 LOC105371592 Ensembl:ENSG00000262050 +105371595 LINC02002 HGNC:HGNC:52837 +105371597 LOC105371597 - +105371598 LOC105371598 - +105371600 LOC105371600 - +105371601 LOC105371601 - +105371604 LOC105371604 - +105371605 LOC105371605 - +105371606 LOC105371606 - +105371608 LOC105371608 - +105371609 LINC01681 HGNC:HGNC:52468 +105371610 LOC105371610 - +105371611 LOC105371611 - +105371612 LOC105371612 - +105371614 LOC105371614 - +105371618 LOC105371618 - +105371619 LOC105371619 - +105371620 LOC105371620 Ensembl:ENSG00000224977 +105371622 LOC105371622 - +105371623 LOC105371623 - +105371625 LOC105371625 - +105371629 LOC105371629 - +105371630 LOC105371630 - +105371631 LOC105371631 - +105371632 LOC105371632 - +105371634 LOC105371634 - +105371635 LOC105371635 - +105371636 LOC105371636 - +105371637 LOC105371637 - +105371638 LOC105371638 - +105371640 LOC105371640 - +105371642 LOC105371642 - +105371644 LINC01688 HGNC:HGNC:52475 +105371646 LOC105371646 - +105371648 LOC105371648 - +105371649 LOC105371649 - +105371651 LOC105371651 - +105371653 GS1-204I12.4 - +105371654 LOC105371654 - +105371655 LOC105371655 - +105371656 LOC105371656 - +105371657 LOC105371657 - +105371658 LOC105371658 - +105371659 LOC105371659 - +105371660 LINC01680 HGNC:HGNC:52467|Ensembl:ENSG00000233882 +105371661 LOC105371661 - +105371662 LOC105371662 - +105371664 LOC105371664 - +105371665 LOC105371665 - +105371667 LOC105371667 - +105371668 LOC105371668 - +105371670 LOC105371670 - +105371671 LOC105371671 - +105371672 LOC105371672 - +105371673 LINC01724 HGNC:HGNC:52512 +105371674 LOC105371674 - +105371675 LOC105371675 - +105371677 LOC105371677 - +105371679 LOC105371679 - +105371680 LOC105371680 - +105371682 LOC105371682 - +105371683 LOC105371683 - +105371684 LOC105371684 - +105371686 LOC105371686 - +105371687 LOC105371687 - +105371688 LOC105371688 - +105371689 LOC105371689 - +105371692 LOC105371692 - +105371693 LOC105371693 - +105371694 LOC105371694 - +105371695 LOC105371695 - +105371698 LOC105371698 - +105371700 LOC105371700 - +105371701 LOC105371701 - +105371702 LOC105371702 - +105371703 LOC105371703 - +105371704 LOC105371704 - +105371705 LOC105371705 - +105371708 LINC01992 HGNC:HGNC:52824 +105371709 LOC105371709 - +105371710 LOC105371710 - +105371711 LOC105371711 - +105371712 LOC105371712 - +105371716 LOC105371716 - +105371720 LOC105371720 - +105371721 LOC105371721 - +105371722 LOC105371722 - +105371723 LOC105371723 - +105371725 LOC105371725 - +105371727 LOC105371727 - +105371729 LOC105371729 - +105371730 LOC105371730 Ensembl:ENSG00000214708 +105371731 LOC105371731 - +105371732 LOC105371732 - +105371734 LOC105371734 - +105371735 LOC105371735 - +105371736 LOC105371736 - +105371737 LOC105371737 - +105371738 LOC105371738 - +105371739 LOC105371739 - +105371740 LOC105371740 - +105371741 LOC105371741 - +105371742 LOC105371742 - +105371743 LINC02001 HGNC:HGNC:52836 +105371744 LOC105371744 - +105371745 LOC105371745 - +105371746 LOC105371746 - +105371747 LOC105371747 - +105371748 LOC105371748 - +105371749 LOC105371749 - +105371750 LOC105371750 - +105371751 LOC105371751 - +105371753 LOC105371753 - +105371754 LOC105371754 - +105371755 LOC105371755 - +105371756 LOC105371756 - +105371757 LOC105371757 - +105371760 LOC105371760 - +105371761 LOC105371761 - +105371762 LOC105371762 - +105371763 LOC105371763 - +105371764 LOC105371764 - +105371766 LINC02079 HGNC:HGNC:52927|Ensembl:ENSG00000266013 +105371767 LOC105371767 - +105371768 LOC105371768 - +105371770 LOC105371770 - +105371771 LOC105371771 - +105371773 LOC105371773 - +105371775 LOC105371775 - +105371776 LOC105371776 - +105371777 LOC105371777 - +105371778 LOC105371778 - +105371781 LOC105371781 - +105371785 LOC105371785 - +105371786 LOC105371786 - +105371787 LOC105371787 - +105371788 LOC105371788 - +105371789 LOC105371789 Ensembl:ENSG00000267638 +105371790 LOC105371790 - +105371791 LOC105371791 - +105371792 LOC105371792 - +105371793 LOC105371793 - +105371794 LOC105371794 - +105371795 LOC105371795 Ensembl:ENSG00000267288 +105371796 LOC105371796 - +105371798 LINC01974 HGNC:HGNC:52801 +105371799 LOC105371799 - +105371800 LOC105371800 - +105371801 LOC105371801 - +105371802 LOC105371802 - +105371807 THRA1/BTR Ensembl:ENSG00000235300 +105371808 LOC105371808 - +105371809 LINC02086 HGNC:HGNC:52936 +105371811 LOC105371811 - +105371812 LOC105371812 - +105371813 LOC105371813 - +105371814 LOC105371814 Ensembl:ENSG00000248278 +105371816 LOC105371816 - +105371817 LOC105371817 - +105371818 LOC105371818 - +105371819 LOC105371819 - +105371820 LOC105371820 - +105371822 LOC105371822 - +105371824 LOC105371824 Ensembl:ENSG00000250286 +105371825 LOC105371825 - +105371828 LINC02073 HGNC:HGNC:52919 +105371829 LOC105371829 - +105371830 LINC01982 HGNC:HGNC:52812 +105371831 LINC02089 HGNC:HGNC:52940 +105371833 LOC105371833 - +105371836 LOC105371836 - +105371839 LOC105371839 - +105371840 LOC105371840 - +105371841 LOC105371841 - +105371842 LOC105371842 - +105371843 LOC105371843 - +105371844 LOC105371844 - +105371845 LOC105371845 - +105371847 LOC105371847 - +105371848 LOC105371848 - +105371849 LOC105371849 Ensembl:ENSG00000267416 +105371850 LOC105371850 - +105371853 LOC105371853 - +105371854 LOC105371854 - +105371855 LOC105371855 - +105371856 LOC105371856 - +105371857 LOC105371857 - +105371858 LOC105371858 - +105371860 LOC105371860 - +105371864 LOC105371864 - +105371865 LOC105371865 - +105371867 LOC105371867 - +105371870 LOC105371870 - +105371871 LOC105371871 - +105371873 LOC105371873 - +105371874 LOC105371874 - +105371877 LOC105371877 - +105371878 LOC105371878 - +105371879 LOC105371879 - +105371880 LOC105371880 - +105371881 LOC105371881 - +105371882 LOC105371882 - +105371884 LOC105371884 - +105371887 LOC105371887 - +105371888 LOC105371888 - +105371891 LOC105371891 - +105371893 LOC105371893 - +105371894 LOC105371894 - +105371896 LOC105371896 - +105371898 LOC105371898 - +105371899 LOC105371899 Ensembl:ENSG00000267568 +105371900 LOC105371900 - +105371901 LOC105371901 - +105371903 LOC105371903 - +105371906 LACAT1 - +105371907 LOC105371907 Ensembl:ENSG00000263718 +105371908 LOC105371908 - +105371909 LOC105371909 - +105371910 LOC105371910 - +105371912 LOC105371912 - +105371919 LINC01977 HGNC:HGNC:52804|Ensembl:ENSG00000262772 +105371921 LOC105371921 - +105371922 LOC105371922 - +105371925 LOC105371925 - +105371926 LOC105371926 - +105371927 LINC01971 HGNC:HGNC:52797 +105371929 LOC105371929 - +105371930 LOC105371930 - +105371932 LOC105371932 - +105371933 LOC105371933 - +105371934 LOC105371934 - +105371936 LOC105371936 - +105371939 LOC105371939 - +105371941 LOC105371941 - +105371942 LOC105371942 - +105371944 LOC105371944 - +105371947 LOC105371947 - +105371948 LOC105371948 - +105371950 LOC105371950 - +105371951 LOC105371951 - +105371952 LOC105371952 - +105371953 LOC105371953 - +105371954 LOC105371954 - +105371956 LOC105371956 - +105371957 LOC105371957 - +105371958 LOC105371958 - +105371959 LOC105371959 - +105371960 LOC105371960 - +105371961 LOC105371961 - +105371962 LOC105371962 - +105371963 LOC105371963 - +105371964 LINC01895 HGNC:HGNC:52714 +105371965 LOC105371965 - +105371967 LOC105371967 - +105371968 LOC105371968 - +105371969 LINC01892 HGNC:HGNC:52711 +105371970 LOC105371970 - +105371972 LOC105371972 - +105371973 LOC105371973 - +105371974 LOC105371974 - +105371975 LOC105371975 - +105371976 LOC105371976 - +105371980 LOC105371980 - +105371981 LOC105371981 - +105371982 LOC105371982 - +105371983 LOC105371983 - +105371984 LOC105371984 - +105371985 LOC105371985 - +105371986 LOC105371986 - +105371987 LOC105371987 - +105371988 LOC105371988 - +105371989 LOC105371989 - +105371990 LOC105371990 - +105371992 LOC105371992 - +105371993 LOC105371993 - +105371994 LINC01928 HGNC:HGNC:52750 +105371995 LOC105371995 - +105371996 LOC105371996 - +105371998 LOC105371998 - +105372001 LOC105372001 - +105372002 LOC105372002 - +105372003 LOC105372003 - +105372004 LOC105372004 - +105372005 LOC105372005 - +105372006 LOC105372006 - +105372007 LOC105372007 - +105372008 LOC105372008 - +105372009 LOC105372009 - +105372010 LOC105372010 - +105372011 LINC01906 HGNC:HGNC:52725 +105372016 LOC105372016 - +105372017 LOC105372017 - +105372018 LOC105372018 - +105372019 LOC105372019 - +105372022 LOC105372022 - +105372023 LOC105372023 - +105372026 LOC105372026 - +105372027 LOC105372027 - +105372028 LOC105372028 Ensembl:ENSG00000266573 +105372029 LOC105372029 - +105372030 LINC01894 HGNC:HGNC:52713 +105372031 LOC105372031 - +105372034 LOC105372034 - +105372035 LOC105372035 - +105372036 LOC105372036 - +105372037 LINC01908 HGNC:HGNC:52727 +105372038 LOC105372038 Ensembl:ENSG00000264151 +105372039 LOC105372039 - +105372040 LOC105372040 - +105372041 LOC105372041 - +105372042 LOC105372042 - +105372043 LOC105372043 - +105372044 LOC105372044 - +105372045 LOC105372045 - +105372046 LOC105372046 - +105372047 LOC105372047 - +105372049 LOC105372049 - +105372055 LOC105372055 - +105372058 LOC105372058 - +105372059 LOC105372059 - +105372061 LOC105372061 - +105372063 LOC105372063 - +105372064 LOC105372064 - +105372065 LOC105372065 - +105372066 LOC105372066 - +105372068 LOC105372068 Ensembl:ENSG00000267202 +105372069 LOC105372069 Ensembl:ENSG00000267039 +105372071 LOC105372071 - +105372072 LOC105372072 - +105372073 LOC105372073 - +105372074 LOC105372074 - +105372075 LOC105372075 - +105372076 LOC105372076 - +105372077 LOC105372077 - +105372079 LINC01902 HGNC:HGNC:52721 +105372080 LINC01901 HGNC:HGNC:52720 +105372081 LOC105372081 - +105372082 LOC105372082 - +105372083 LOC105372083 - +105372084 LOC105372084 - +105372085 LOC105372085 - +105372087 LOC105372087 - +105372088 LOC105372088 - +105372089 LOC105372089 - +105372091 LOC105372091 - +105372092 LOC105372092 - +105372093 LOC105372093 - +105372095 LOC105372095 - +105372096 LOC105372096 - +105372097 LOC105372097 - +105372098 LOC105372098 - +105372100 LOC105372100 - +105372101 LOC105372101 - +105372104 LOC105372104 - +105372105 LOC105372105 - +105372106 LOC105372106 - +105372107 LOC105372107 - +105372108 LOC105372108 - +105372109 LOC105372109 - +105372110 LOC105372110 - +105372112 LOC105372112 - +105372114 LOC105372114 - +105372115 LOC105372115 - +105372116 LOC105372116 - +105372117 LOC105372117 - +105372118 LOC105372118 - +105372119 LOC105372119 - +105372120 LOC105372120 - +105372121 LOC105372121 - +105372123 LOC105372123 - +105372124 LOC105372124 - +105372125 LOC105372125 - +105372126 LOC105372126 - +105372127 TCF4-AS1 HGNC:HGNC:51642|Ensembl:ENSG00000267028 +105372130 LOC105372130 - +105372131 LOC105372131 - +105372132 LOC105372132 - +105372133 LOC105372133 - +105372135 LOC105372135 - +105372136 LOC105372136 - +105372138 LINC02565 HGNC:HGNC:53605 +105372139 LOC105372139 - +105372140 LOC105372140 - +105372141 LOC105372141 - +105372143 LOC105372143 Ensembl:ENSG00000267743 +105372145 LOC105372145 - +105372146 LOC105372146 - +105372147 LINC01926 HGNC:HGNC:52748 +105372151 LOC105372151 - +105372152 LOC105372152 - +105372155 LOC105372155 - +105372156 LOC105372156 - +105372157 LOC105372157 - +105372158 LOC105372158 - +105372159 LOC105372159 - +105372160 LOC105372160 - +105372161 LOC105372161 - +105372165 LOC105372165 - +105372166 LOC105372166 - +105372167 LOC105372167 - +105372168 LOC105372168 - +105372169 LOC105372169 - +105372170 LOC105372170 - +105372171 LOC105372171 - +105372172 LOC105372172 - +105372173 LOC105372173 - +105372174 LOC105372174 - +105372175 LINC01912 HGNC:HGNC:52731 +105372178 LOC105372178 - +105372179 LOC105372179 Ensembl:ENSG00000264845 +105372180 LOC105372180 - +105372185 LOC105372185 - +105372186 LOC105372186 - +105372187 LOC105372187 - +105372188 LOC105372188 - +105372189 LOC105372189 - +105372190 LOC105372190 - +105372191 LOC105372191 - +105372194 LOC105372194 - +105372200 LOC105372200 - +105372201 LOC105372201 - +105372202 LOC105372202 - +105372203 LOC105372203 - +105372204 LOC105372204 - +105372206 LOC105372206 - +105372207 LINC01893 HGNC:HGNC:52712 +105372208 LOC105372208 - +105372209 LOC105372209 - +105372210 LOC105372210 - +105372211 LOC105372211 - +105372212 LOC105372212 - +105372213 LOC105372213 - +105372214 LOC105372214 - +105372217 LOC105372217 - +105372218 LOC105372218 - +105372219 LOC105372219 - +105372220 LOC105372220 - +105372221 LOC105372221 - +105372224 LOC105372224 - +105372225 LOC105372225 - +105372226 LOC105372226 - +105372228 LOC105372228 - +105372229 LOC105372229 - +105372232 LOC105372232 - +105372233 LOC105372233 Ensembl:ENSG00000267751 +105372234 LOC105372234 - +105372235 LOC105372235 - +105372236 LOC105372236 - +105372238 LOC105372238 - +105372240 LOC105372240 Ensembl:ENSG00000167476 +105372242 LOC105372242 - +105372243 LOC105372243 - +105372244 LOC105372244 - +105372245 LOC105372245 - +105372246 LOC105372246 - +105372248 LOC105372248 - +105372249 LOC105372249 - +105372250 LOC105372250 - +105372252 LOC105372252 - +105372253 LOC105372253 - +105372255 LOC105372255 - +105372256 LOC105372256 - +105372257 LOC105372257 Ensembl:ENSG00000268845 +105372260 LOC105372260 - +105372261 LOC105372261 - +105372262 LOC105372262 - +105372263 LOC105372263 - +105372266 LOC105372266 - +105372267 LINC01862 HGNC:HGNC:52681|Ensembl:ENSG00000268480 +105372268 LOC105372268 - +105372269 LOC105372269 - +105372270 LOC105372270 - +105372272 LOC105372272 - +105372273 LOC105372273 Ensembl:ENSG00000267082 +105372274 HSPC102 - +105372275 LOC105372275 - +105372278 LOC105372278 - +105372279 LOC105372279 - +105372280 GNG14 HGNC:HGNC:53439|Ensembl:ENSG00000283980 +105372281 LOC105372281 - +105372282 LOC105372282 - +105372283 LOC105372283 - +105372284 LOC105372284 - +105372288 LINC01841 HGNC:HGNC:52655|Ensembl:ENSG00000266913 +105372290 LINC01764 HGNC:HGNC:52553|Ensembl:ENSG00000267308 +105372291 LOC105372291 - +105372292 LINC01855 HGNC:HGNC:52675|Ensembl:ENSG00000267517 +105372295 LOC105372295 - +105372296 LOC105372296 - +105372297 LOC105372297 - +105372298 LOC105372298 - +105372299 LOC105372299 - +105372300 LOC105372300 - +105372302 LOC105372302 - +105372303 LOC105372303 - +105372308 LOC105372308 - +105372309 LOC105372309 - +105372310 LOC105372310 - +105372311 LOC105372311 - +105372314 LOC105372314 - +105372315 LOC105372315 - +105372316 LOC105372316 - +105372317 LOC105372317 - +105372318 LOC105372318 - +105372319 LOC105372319 - +105372321 LOC105372321 - +105372323 LOC105372323 - +105372324 LOC105372324 - +105372325 LOC105372325 - +105372326 LOC105372326 - +105372328 LOC105372328 - +105372330 LOC105372330 - +105372331 LOC105372331 - +105372332 LOC105372332 - +105372333 LOC105372333 - +105372334 LOC105372334 - +105372335 LOC105372335 - +105372337 LOC105372337 - +105372338 LOC105372338 - +105372339 LOC105372339 - +105372343 LOC105372343 Ensembl:ENSG00000269720|Vega:OTTHUMG00000191663 +105372345 LOC105372345 - +105372346 LOC105372346 - +105372347 LOC105372347 - +105372348 LOC105372348 - +105372349 LOC105372349 - +105372352 LOC105372352 Ensembl:ENSG00000267498 +105372353 LOC105372353 - +105372354 LOC105372354 - +105372355 LOC105372355 - +105372356 LOC105372356 - +105372358 LOC105372358 - +105372360 LOC105372360 - +105372361 LOC105372361 - +105372362 LOC105372362 - +105372363 LINC01837 HGNC:HGNC:52653 +105372364 LOC105372364 - +105372368 LOC105372368 - +105372370 LOC105372370 - +105372371 LOC105372371 - +105372374 LOC105372374 - +105372375 LOC105372375 - +105372377 LOC105372377 - +105372379 LOC105372379 - +105372380 LOC105372380 - +105372383 LOC105372383 - +105372385 LOC105372385 - +105372390 LOC105372390 - +105372392 LOC105372392 - +105372394 LOC105372394 - +105372395 LOC105372395 - +105372396 LOC105372396 - +105372397 LOC105372397 Ensembl:ENSG00000267291 +105372399 LOC105372399 - +105372401 LOC105372401 - +105372404 LOC105372404 - +105372405 LOC105372405 - +105372407 LOC105372407 - +105372410 LOC105372410 - +105372411 LOC105372411 - +105372412 LOC105372412 - +105372414 LOC105372414 - +105372419 LOC105372419 Ensembl:ENSG00000267348 +105372420 LOC105372420 - +105372421 LOC105372421 - +105372424 LOC105372424 - +105372426 LOC105372426 - +105372427 LOC105372427 - +105372429 LOC105372429 - +105372430 LOC105372430 Ensembl:ENSG00000268530 +105372431 LOC105372431 - +105372432 LOC105372432 - +105372433 LOC105372433 - +105372434 LOC105372434 - +105372435 LOC105372435 - +105372436 LOC105372436 - +105372437 LOC105372437 - +105372439 LOC105372439 - +105372440 LOC105372440 Ensembl:ENSG00000261341|Vega:OTTHUMG00000176604 +105372441 LOC105372441 Ensembl:ENSG00000267968 +105372442 LOC105372442 - +105372444 LINC01872 HGNC:HGNC:52691|Ensembl:ENSG00000268318 +105372446 LOC105372446 - +105372448 LOC105372448 - +105372449 LOC105372449 - +105372451 LOC105372451 - +105372452 LOC105372452 - +105372453 LOC105372453 - +105372454 LOC105372454 - +105372457 LOC105372457 - +105372458 LOC105372458 - +105372460 LOC105372460 - +105372461 LOC105372461 - +105372462 LOC105372462 - +105372464 LOC105372464 - +105372465 LOC105372465 - +105372468 LOC105372468 - +105372470 LOC105372470 - +105372471 LOC105372471 - +105372472 LOC105372472 - +105372473 LOC105372473 - +105372474 LOC105372474 - +105372475 LOC105372475 - +105372476 LOC105372476 Ensembl:ENSG00000267871 +105372478 LOC105372478 - +105372479 LOC105372479 - +105372480 LOC105372480 - +105372481 ERVK3-1 HGNC:HGNC:30466|Ensembl:ENSG00000142396|Vega:OTTHUMG00000150367 +105372482 LOC105372482 Ensembl:ENSG00000268516 +105372483 LOC105372483 Ensembl:ENSG00000269054 +105372484 LOC105372484 - +105372485 LOC105372485 - +105372486 LOC105372486 - +105372489 LOC105372489 - +105372491 LOC105372491 - +105372492 LOC105372492 - +105372493 LOC105372493 Ensembl:ENSG00000276026 +105372494 LOC105372494 - +105372495 LOC105372495 - +105372496 LOC105372496 - +105372497 LOC105372497 - +105372498 LOC105372498 - +105372499 LOC105372499 - +105372501 LOC105372501 - +105372502 LOC105372502 - +105372503 LOC105372503 - +105372504 LOC105372504 - +105372505 LOC105372505 - +105372506 LOC105372506 - +105372507 LOC105372507 - +105372508 LOC105372508 - +105372509 LOC105372509 - +105372510 LOC105372510 - +105372511 LOC105372511 - +105372513 LOC105372513 - +105372514 LOC105372514 - +105372516 LINC01713 HGNC:HGNC:52500 +105372517 LOC105372517 - +105372518 LOC105372518 - +105372520 LOC105372520 - +105372521 LOC105372521 - +105372522 LOC105372522 - +105372523 LOC105372523 - +105372524 LOC105372524 - +105372525 LOC105372525 - +105372527 LOC105372527 - +105372528 LOC105372528 - +105372529 LOC105372529 - +105372530 LOC105372530 - +105372531 LOC105372531 - +105372532 LOC105372532 - +105372535 LOC105372535 - +105372539 LOC105372539 - +105372541 LOC105372541 - +105372542 LOC105372542 - +105372543 LOC105372543 - +105372544 LOC105372544 - +105372545 LOC105372545 - +105372546 LOC105372546 - +105372547 LOC105372547 - +105372548 LOC105372548 - +105372549 LOC105372549 - +105372550 LOC105372550 - +105372551 LOC105372551 - +105372553 LOC105372553 - +105372554 LOC105372554 - +105372555 LOC105372555 - +105372556 LINC00237 MIM:614992|HGNC:HGNC:38166 +105372558 LOC105372558 - +105372560 LOC105372560 - +105372561 LOC105372561 - +105372562 LOC105372562 - +105372563 LOC105372563 - +105372564 LOC105372564 - +105372566 LINC01747 HGNC:HGNC:52536|Ensembl:ENSG00000230400 +105372567 LOC105372567 - +105372568 LOC105372568 - +105372569 LOC105372569 - +105372571 LOC105372571 - +105372572 LOC105372572 - +105372573 LOC105372573 - +105372574 LOC105372574 - +105372575 LOC105372575 - +105372576 LOC105372576 - +105372577 LOC105372577 - +105372578 LOC105372578 - +105372579 LOC105372579 - +105372580 LOC105372580 - +105372581 LOC105372581 - +105372582 LOC105372582 - +105372585 LOC105372585 - +105372586 LOC105372586 - +105372587 LOC105372587 - +105372588 LOC105372588 - +105372589 LOC105372589 - +105372592 LOC105372592 - +105372593 LOC105372593 - +105372594 LOC105372594 - +105372599 LOC105372599 - +105372600 LOC105372600 - +105372602 LOC105372602 - +105372606 LOC105372606 - +105372608 LINC01746 HGNC:HGNC:52534 +105372609 LOC105372609 - +105372613 LOC105372613 - +105372614 LOC105372614 - +105372616 LOC105372616 - +105372617 LOC105372617 - +105372618 LOC105372618 - +105372620 LOC105372620 - +105372621 LOC105372621 - +105372622 LOC105372622 - +105372623 LOC105372623 - +105372624 LOC105372624 - +105372625 LOC105372625 - +105372626 LINC01728 HGNC:HGNC:52516|Ensembl:ENSG00000233277 +105372629 LOC105372629 - +105372630 LOC105372630 - +105372631 LOC105372631 - +105372632 LOC105372632 - +105372633 LOC105372633 - +105372636 LOC105372636 - +105372637 LOC105372637 - +105372639 LOC105372639 - +105372640 LOC105372640 - +105372641 LOC105372641 - +105372643 LOC105372643 - +105372644 LOC105372644 - +105372645 LOC105372645 - +105372646 LOC105372646 - +105372647 LOC105372647 - +105372648 LOC105372648 - +105372649 LOC105372649 - +105372651 LOC105372651 - +105372652 LOC105372652 - +105372653 LOC105372653 - +105372654 LOC105372654 - +105372655 LOC105372655 - +105372656 LOC105372656 - +105372657 LOC105372657 - +105372659 LOC105372659 - +105372661 LOC105372661 - +105372662 LOC105372662 - +105372663 LOC105372663 - +105372664 LOC105372664 - +105372665 LOC105372665 - +105372666 LOC105372666 - +105372667 LOC105372667 - +105372668 LOC105372668 - +105372669 LOC105372669 - +105372670 LOC105372670 - +105372671 LOC105372671 - +105372672 LOC105372672 Ensembl:ENSG00000235415 +105372675 LOC105372675 - +105372676 LOC105372676 - +105372677 LOC105372677 - +105372678 LOC105372678 - +105372679 LOC105372679 - +105372680 LOC105372680 - +105372681 LOC105372681 - +105372682 LINC01716 HGNC:HGNC:52503|Ensembl:ENSG00000225657 +105372683 LOC105372683 - +105372685 LOC105372685 - +105372686 LOC105372686 - +105372687 LOC105372687 - +105372688 LOC105372688 - +105372690 LOC105372690 - +105372692 LOC105372692 - +105372693 LOC105372693 - +105372694 LOC105372694 - +105372695 LOC105372695 - +105372696 LOC105372696 - +105372697 LOC105372697 - +105372698 LOC105372698 - +105372699 LOC105372699 - +105372700 LOC105372700 - +105372701 LOC105372701 - +105372703 LOC105372703 - +105372704 LOC105372704 - +105372705 LOC105372705 - +105372706 LOC105372706 - +105372707 LOC105372707 - +105372708 LOC105372708 - +105372709 LOC105372709 - +105372710 LOC105372710 - +105372711 LOC105372711 - +105372712 WI2-87327B8.2 - +105372714 LOC105372714 - +105372716 LOC105372716 - +105372717 LOC105372717 - +105372718 LOC105372718 - +105372719 LOC105372719 - +105372720 LOC105372720 - +105372721 LOC105372721 - +105372724 LOC105372724 - +105372725 LOC105372725 - +105372726 LOC105372726 - +105372727 LOC105372727 - +105372728 LOC105372728 - +105372730 LINC01666 HGNC:HGNC:52454 +105372731 LOC105372731 - +105372733 LOC105372733 - +105372734 LOC105372734 - +105372736 LOC105372736 - +105372738 LOC105372738 - +105372739 LOC105372739 - +105372740 LOC105372740 - +105372741 LOC105372741 - +105372745 LOC105372745 - +105372746 LINC01683 HGNC:HGNC:52471|Ensembl:ENSG00000233480 +105372747 LOC105372747 - +105372749 LOC105372749 - +105372750 LOC105372750 - +105372751 LINC01684 HGNC:HGNC:52472|Ensembl:ENSG00000237484 +105372753 LOC105372753 - +105372754 LOC105372754 - +105372756 LOC105372756 - +105372757 LOC105372757 - +105372758 LOC105372758 - +105372759 LOC105372759 - +105372760 LOC105372760 - +105372762 LOC105372762 - +105372763 LINC01673 HGNC:HGNC:52461 +105372764 LOC105372764 - +105372766 LOC105372766 - +105372767 LOC105372767 - +105372768 LOC105372768 - +105372770 LOC105372770 - +105372772 LOC105372772 - +105372773 LOC105372773 - +105372774 LOC105372774 - +105372775 LOC105372775 - +105372776 LOC105372776 - +105372777 LOC105372777 - +105372779 LOC105372779 - +105372781 LOC105372781 - +105372782 LOC105372782 - +105372785 LOC105372785 - +105372787 LOC105372787 - +105372789 LOC105372789 - +105372790 LOC105372790 - +105372791 LOC105372791 - +105372792 LOC105372792 - +105372793 LOC105372793 - +105372795 LOC105372795 - +105372796 LOC105372796 - +105372797 LOC105372797 - +105372798 LOC105372798 - +105372799 KCNJ6-AS1 HGNC:HGNC:41352 +105372801 LOC105372801 - +105372802 LOC105372802 - +105372803 LOC105372803 - +105372804 LOC105372804 - +105372807 LOC105372807 - +105372808 LOC105372808 - +105372809 LOC105372809 - +105372812 LOC105372812 - +105372813 LOC105372813 - +105372814 LOC105372814 - +105372815 LOC105372815 - +105372816 LOC105372816 - +105372817 LOC105372817 - +105372821 LOC105372821 - +105372823 LOC105372823 - +105372824 LOC105372824 Ensembl:ENSG00000160209 +105372825 LOC105372825 - +105372826 LOC105372826 - +105372829 LOC105372829 - +105372831 CH507-9B2.8 - +105372832 LOC105372832 - +105372833 LOC105372833 Ensembl:ENSG00000232010 +105372835 LOC105372835 - +105372836 LOC105372836 - +105372837 LOC105372837 - +105372838 LOC105372838 - +105372839 LOC105372839 - +105372840 LINC01694 HGNC:HGNC:52481|Ensembl:ENSG00000233922 +105372841 LOC105372841 - +105372842 LOC105372842 - +105372850 LOC105372850 - +105372853 LOC105372853 - +105372856 LOC105372856 - +105372857 LOC105372857 - +105372858 LOC105372858 - +105372859 LOC105372859 - +105372860 LOC105372860 - +105372861 LOC105372861 - +105372862 LOC105372862 - +105372863 LOC105372863 - +105372864 LOC105372864 - +105372865 LOC105372865 - +105372866 LOC105372866 - +105372868 LOC105372868 - +105372869 LOC105372869 - +105372871 LOC105372871 - +105372873 LOC105372873 - +105372875 LOC105372875 - +105372876 LOC105372876 - +105372877 LOC105372877 - +105372878 LOC105372878 - +105372879 LOC105372879 - +105372880 LOC105372880 - +105372881 LOC105372881 - +105372883 LOC105372883 - +105372884 LOC105372884 - +105372887 LOC105372887 - +105372888 LOC105372888 - +105372889 LOC105372889 - +105372891 LOC105372891 - +105372892 LOC105372892 - +105372893 LINC01717 HGNC:HGNC:52504 +105372894 LINC01774 HGNC:HGNC:52564|Ensembl:ENSG00000236950 +105372895 LOC105372895 - +105372896 LOC105372896 - +105372897 LINC01696 HGNC:HGNC:52484|Ensembl:ENSG00000227940 +105372898 LOC105372898 - +105372899 LOC105372899 - +105372901 LOC105372901 - +105372902 LOC105372902 - +105372903 LOC105372903 - +105372904 LOC105372904 - +105372906 LOC105372906 - +105372907 LOC105372907 - +105372908 LOC105372908 - +105372909 LOC105372909 - +105372911 LOC105372911 - +105372912 LOC105372912 - +105372915 LOC105372915 - +105372916 LOC105372916 - +105372918 LOC105372918 - +105372919 LOC105372919 - 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LOC105373222 - +105373223 LOC105373223 - +105373224 LOC105373224 - +105373225 LOC105373225 - +105373228 LOC105373228 - +105373230 LOC105373230 - +105373231 LOC105373231 - +105373233 LOC105373233 - +105373234 LOC105373234 - +105373235 LOC105373235 - +105373239 LOC105373239 - +105373240 LOC105373240 - +105373241 LOC105373241 - +105373242 LOC105373242 - +105373244 LOC105373244 - +105373247 LOC105373247 - +105373249 LOC105373249 - +105373250 LOC105373250 - +105373251 FAM236D HGNC:HGNC:52642 +105373252 LOC105373252 - +105373254 LOC105373254 - +105373255 LOC105373255 - +105373258 LOC105373258 - +105373260 LOC105373260 - +105373261 LOC105373261 - +105373262 LOC105373262 - +105373264 LOC105373264 - +105373265 LOC105373265 - +105373266 LOC105373266 - +105373269 LOC105373269 - +105373270 LOC105373270 - +105373271 LOC105373271 - +105373273 LOC105373273 - +105373274 LOC105373274 - +105373275 LOC105373275 - +105373276 LOC105373276 - +105373277 LOC105373277 - +105373278 LOC105373278 - +105373279 LOC105373279 - +105373281 LOC105373281 - +105373282 LOC105373282 - +105373283 LOC105373283 - +105373284 LOC105373284 - +105373285 LOC105373285 - +105373286 LOC105373286 - +105373287 LOC105373287 - +105373288 LOC105373288 - +105373289 LOC105373289 - +105373291 LOC105373291 - +105373292 LOC105373292 - +105373293 LOC105373293 - +105373294 LOC105373294 - +105373296 LOC105373296 - +105373297 LOC105373297 - +105373298 LOC105373298 - +105373299 LOC105373299 - +105373300 LOC105373300 - +105373302 LOC105373302 - +105373303 LOC105373303 - +105373304 LOC105373304 - +105373305 LOC105373305 - +105373306 LOC105373306 - +105373308 LOC105373308 - +105373310 LOC105373310 - +105373311 LOC105373311 - +105373312 LOC105373312 - +105373313 LOC105373313 - +105373314 LOC105373314 - +105373315 LOC105373315 - +105373316 LOC105373316 - +105373318 LOC105373318 - +105373320 LOC105373320 - +105373323 LOC105373323 - +105373324 LOC105373324 - +105373328 LOC105373328 - +105373331 LOC105373331 - +105373332 LOC105373332 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Ensembl:ENSG00000063587 +105373379 LOC105373379 - +105373381 LOC105373381 - +105373383 LOC105373383 Ensembl:ENSG00000260081 +105373384 LOC105373384 - +105373386 LOC105373386 - +105373387 LOC105373387 - +105373388 LOC105373388 - +105373389 LOC105373389 - +105373390 LOC105373390 - +105373392 LOC105373392 - +105373393 LOC105373393 - +105373394 LOC105373394 - +105373395 LOC105373395 - +105373397 LOC105373397 - +105373398 LOC105373398 - +105373399 LOC105373399 - +105373400 LINC01810 HGNC:HGNC:52613 +105373401 LOC105373401 - +105373402 LOC105373402 - +105373404 LOC105373404 - +105373405 LOC105373405 - +105373406 LOC105373406 - +105373407 LOC105373407 - +105373408 LOC105373408 - +105373409 LOC105373409 - +105373411 LOC105373411 - +105373412 LOC105373412 - +105373414 LOC105373414 - +105373415 LOC105373415 - +105373416 LOC105373416 - +105373417 LOC105373417 - +105373418 LOC105373418 - +105373419 LOC105373419 - +105373420 LOC105373420 - +105373421 LOC105373421 - +105373422 LOC105373422 - 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LOC105373530 - +105373531 LOC105373531 - +105373534 LOC105373534 - +105373535 LOC105373535 - +105373536 LINC01789 HGNC:HGNC:52578|Ensembl:ENSG00000229457 +105373537 LINC01886 HGNC:HGNC:52705|Ensembl:ENSG00000224568 +105373538 LINC01885 HGNC:HGNC:52704 +105373539 LOC105373539 - +105373543 LOC105373543 - +105373545 LOC105373545 - +105373547 LOC105373547 - +105373548 LOC105373548 - +105373549 LOC105373549 - +105373551 LOC105373551 - +105373552 LOC105373552 - +105373553 LOC105373553 - +105373554 LOC105373554 - +105373557 LOC105373557 - +105373559 LOC105373559 - +105373560 LOC105373560 - +105373562 LOC105373562 - +105373563 LOC105373563 - +105373567 LOC105373567 - +105373570 LOC105373570 - +105373572 LOC105373572 - +105373574 LOC105373574 - +105373575 LOC105373575 - +105373576 LOC105373576 - +105373578 LOC105373578 - +105373579 LOC105373579 - +105373580 LOC105373580 - +105373581 LOC105373581 - +105373582 LOC105373582 - +105373583 LOC105373583 - +105373584 LOC105373584 - +105373585 LOC105373585 - +105373587 LOC105373587 - +105373588 LOC105373588 - +105373590 LOC105373590 - +105373591 LOC105373591 - +105373592 LOC105373592 - +105373593 LOC105373593 - +105373594 LOC105373594 - +105373595 LOC105373595 - +105373596 LOC105373596 - +105373597 LINC01889 HGNC:HGNC:52708 +105373598 LOC105373598 - +105373600 LINC01941 HGNC:HGNC:52764 +105373601 LOC105373601 - +105373602 LOC105373602 - +105373603 LOC105373603 - +105373604 LOC105373604 - +105373605 LOC105373605 - +105373606 LOC105373606 - +105373608 LOC105373608 - +105373609 LOC105373609 - +105373610 LOC105373610 - +105373611 LOC105373611 - +105373612 LOC105373612 - +105373613 LOC105373613 - +105373614 LOC105373614 - +105373615 LOC105373615 - +105373616 LOC105373616 - +105373617 LOC105373617 - +105373618 LOC105373618 - +105373622 LOC105373622 - +105373623 LOC105373623 - +105373627 LOC105373627 - +105373628 LOC105373628 - +105373629 LOC105373629 - +105373632 LOC105373632 - +105373633 LOC105373633 - +105373634 LOC105373634 - +105373635 LINC01832 HGNC:HGNC:52638|Ensembl:ENSG00000224231 +105373636 LOC105373636 - +105373637 LOC105373637 - +105373639 LOC105373639 - +105373640 LOC105373640 - +105373641 LOC105373641 - +105373643 LOC105373643 - +105373644 LOC105373644 - +105373645 LOC105373645 - +105373647 LINC01853 HGNC:HGNC:52669 +105373648 LOC105373648 - +105373649 LOC105373649 - +105373651 LOC105373651 - +105373652 LOC105373652 - +105373654 LOC105373654 - +105373656 LOC105373656 - +105373662 LINC01966 HGNC:HGNC:52792 +105373663 LOC105373663 - +105373664 LOC105373664 - +105373665 LOC105373665 - +105373666 LOC105373666 - +105373667 LOC105373667 - +105373668 LOC105373668 - +105373669 LINC01911 HGNC:HGNC:52730 +105373673 LOC105373673 - +105373674 LOC105373674 - +105373677 LOC105373677 - +105373678 LOC105373678 - +105373679 LOC105373679 - +105373680 LOC105373680 - +105373682 LOC105373682 - +105373683 LINC01817 HGNC:HGNC:52622 +105373684 LINC01818 HGNC:HGNC:52623 +105373685 LOC105373685 - +105373686 LOC105373686 - +105373688 LOC105373688 - +105373689 LOC105373689 - +105373690 LOC105373690 - +105373691 LOC105373691 - +105373692 LOC105373692 - +105373693 LOC105373693 - +105373694 LOC105373694 - +105373696 LOC105373696 - +105373698 LOC105373698 - +105373699 LOC105373699 - +105373700 LOC105373700 - +105373703 LOC105373703 - +105373707 LOC105373707 - +105373708 LINC01958 HGNC:HGNC:52784 +105373709 LOC105373709 - +105373710 LOC105373710 - +105373711 LOC105373711 - +105373712 LOC105373712 - +105373713 LOC105373713 - +105373714 LOC105373714 - +105373715 LOC105373715 - +105373716 LOC105373716 - +105373717 LOC105373717 - +105373718 LOC105373718 - +105373719 LOC105373719 - +105373720 LOC105373720 - +105373722 LOC105373722 - +105373724 LOC105373724 - +105373727 LOC105373727 - +105373728 LOC105373728 - +105373730 LOC105373730 - +105373733 LOC105373733 - +105373734 LOC105373734 - +105373735 LOC105373735 - +105373736 LOC105373736 - +105373737 LOC105373737 - +105373739 LOC105373739 - +105373740 LOC105373740 - +105373741 LOC105373741 - +105373742 LOC105373742 - +105373743 LOC105373743 - +105373744 LOC105373744 - +105373745 LOC105373745 - +105373746 LOC105373746 - +105373748 LOC105373748 - +105373750 LOC105373750 - +105373752 LOC105373752 - +105373754 LOC105373754 - +105373756 LOC105373756 - +105373757 LOC105373757 - +105373759 LOC105373759 - +105373760 LOC105373760 - +105373762 LOC105373762 - +105373764 LOC105373764 Ensembl:ENSG00000229941 +105373766 LOC105373766 - +105373767 LOC105373767 - +105373768 LOC105373768 - +105373769 LOC105373769 - +105373770 LOC105373770 - +105373771 LOC105373771 - +105373772 LOC105373772 - +105373774 LOC105373774 - +105373775 LOC105373775 - +105373776 LOC105373776 - +105373777 LOC105373777 - +105373779 LOC105373779 - +105373780 LOC105373780 - +105373781 LOC105373781 - +105373782 LOC105373782 - +105373785 LOC105373785 - +105373786 LOC105373786 - +105373788 LOC105373788 - +105373790 LOC105373790 - +105373791 LOC105373791 - +105373793 LOC105373793 - +105373794 LOC105373794 - +105373795 LOC105373795 - +105373796 LOC105373796 - +105373802 LOC105373802 - +105373804 LOC105373804 - +105373805 LOC105373805 Ensembl:ENSG00000231858 +105373811 LOC105373811 - +105373812 LOC105373812 - +105373813 LOC105373813 - +105373815 LOC105373815 - +105373816 LOC105373816 - +105373817 LOC105373817 - +105373818 LINC01827 HGNC:HGNC:52633|Ensembl:ENSG00000234919 +105373819 LOC105373819 - +105373821 LOC105373821 - +105373822 LOC105373822 - +105373823 LOC105373823 - +105373824 LOC105373824 - +105373826 LOC105373826 - +105373828 LOC105373828 - +105373830 LOC105373830 - +105373831 LOC105373831 - +105373833 LOC105373833 - +105373834 LOC105373834 - +105373835 LOC105373835 - +105373836 LOC105373836 - +105373845 LOC105373845 - +105373847 LOC105373847 - +105373848 LOC105373848 - +105373851 LOC105373851 - +105373852 LINC01802 HGNC:HGNC:52591 +105373853 MYOSLID HGNC:HGNC:51821 +105373854 LOC105373854 - +105373855 LOC105373855 - +105373856 LOC105373856 - +105373857 LOC105373857 - +105373863 LINC01953 HGNC:HGNC:52776 +105373864 LOC105373864 - +105373868 LOC105373868 - +105373869 LINC01614 HGNC:HGNC:51847 +105373870 LOC105373870 - +105373871 LOC105373871 - +105373872 LOC105373872 - +105373873 LOC105373873 - +105373874 LOC105373874 - +105373876 LOC105373876 Ensembl:ENSG00000237479 +105373877 DIRC3-AS1 HGNC:HGNC:50636 +105373878 LOC105373878 Ensembl:ENSG00000223923 +105373880 LOC105373880 - +105373881 LOC105373881 - +105373882 LOC105373882 - +105373883 LOC105373883 - +105373884 LOC105373884 - +105373885 LOC105373885 - +105373886 LOC105373886 - +105373887 LOC105373887 - +105373888 LOC105373888 - +105373889 LINC01803 HGNC:HGNC:52595 +105373890 LOC105373890 - +105373891 LOC105373891 - +105373893 LOC105373893 - +105373894 LOC105373894 - +105373895 LOC105373895 - +105373896 LOC105373896 - +105373897 LOC105373897 - +105373898 LOC105373898 - +105373899 LOC105373899 - +105373900 LOC105373900 - +105373901 LOC105373901 - +105373902 LOC105373902 - +105373903 LOC105373903 - +105373904 LOC105373904 - +105373905 LOC105373905 - +105373906 LOC105373906 - +105373907 LOC105373907 - +105373908 LOC105373908 - +105373909 LOC105373909 - +105373910 LOC105373910 - +105373911 LOC105373911 - +105373914 LOC105373914 - +105373915 LOC105373915 - +105373918 LOC105373918 - +105373919 LOC105373919 - +105373920 LOC105373920 - +105373921 LOC105373921 - +105373923 LOC105373923 - +105373924 LOC105373924 - +105373925 LOC105373925 - +105373926 LOC105373926 - +105373928 LOC105373928 - +105373929 LOC105373929 - +105373932 LOC105373932 - +105373933 LOC105373933 - +105373934 LINC01891 HGNC:HGNC:52710 +105373936 LOC105373936 - +105373937 LOC105373937 - +105373938 LOC105373938 - +105373939 LOC105373939 - +105373940 LOC105373940 - +105373941 LOC105373941 - +105373942 LOC105373942 - +105373943 LOC105373943 - +105373944 LOC105373944 - +105373945 LOC105373945 - +105373946 LOC105373946 - +105373947 LOC105373947 - +105373948 LOC105373948 - +105373949 LOC105373949 - +105373950 LOC105373950 - +105373951 LOC105373951 - +105373952 LOC105373952 - +105373953 LOC105373953 - +105373954 LOC105373954 - +105373957 LOC105373957 - +105373958 LOC105373958 Ensembl:ENSG00000234949 +105373960 LOC105373960 - +105373961 LOC105373961 - +105373962 LINC01937 HGNC:HGNC:52760 +105373963 LOC105373963 - +105373966 LOC105373966 - +105373968 LOC105373968 - +105373970 LOC105373970 - +105373971 LOC105373971 - +105373973 LOC105373973 - +105373974 LOC105373974 - +105373975 LOC105373975 - +105373976 LOC105373976 - +105373977 LOC105373977 - +105373978 LOC105373978 - +105373979 LINC01880 HGNC:HGNC:52699 +105373980 LOC105373980 - +105373984 LINC01918 HGNC:HGNC:52737|Ensembl:ENSG00000226508 +105373985 LOC105373985 - +105373986 LOC105373986 - +105373989 LOC105373989 - +105373991 LOC105373991 - +105373992 LOC105373992 - +105373994 LOC105373994 - +105373996 LOC105373996 - +105373997 LOC105373997 - +105373998 LOC105373998 - +105373999 LOC105373999 - +105374000 LOC105374000 - +105374002 LOC105374002 Ensembl:ENSG00000239462 +105374003 LOC105374003 - +105374004 LOC105374004 - +105374005 LOC105374005 - +105374006 LOC105374006 - +105374007 LOC105374007 - +105374009 LOC105374009 - +105374010 LOC105374010 - +105374013 LOC105374013 - +105374016 LOC105374016 - +105374017 LOC105374017 - +105374018 LOC105374018 - +105374019 LOC105374019 - +105374020 LOC105374020 - +105374021 LOC105374021 - +105374023 LOC105374023 - +105374024 LOC105374024 - +105374026 LOC105374026 - +105374027 LOC105374027 - +105374029 LOC105374029 - +105374031 LOC105374031 - +105374033 LOC105374033 - +105374034 LOC105374034 - +105374036 LOC105374036 - +105374037 LOC105374037 - +105374038 LOC105374038 - +105374039 LOC105374039 - +105374040 LOC105374040 - +105374041 LOC105374041 - +105374042 LOC105374042 - +105374048 LOC105374048 - +105374051 LOC105374051 - +105374052 LOC105374052 - +105374053 LOC105374053 - +105374054 LOC105374054 - +105374056 LOC105374056 - +105374057 LINC02024 HGNC:HGNC:52859 +105374058 LOC105374058 - +105374059 LOC105374059 - +105374060 LOC105374060 - +105374062 LOC105374062 - +105374063 LOC105374063 - +105374064 LOC105374064 - +105374065 LOC105374065 - +105374069 LOC105374069 - +105374071 LOC105374071 - +105374076 LOC105374076 - +105374077 LOC105374077 - +105374079 LOC105374079 - +105374080 LOC105374080 - +105374081 LOC105374081 - +105374083 LOC105374083 - +105374085 LOC105374085 - +105374086 LOC105374086 - +105374088 LOC105374088 - +105374089 LOC105374089 - +105374090 LOC105374090 - +105374094 LOC105374094 - +105374096 LOC105374096 - +105374101 LOC105374101 - +105374102 LOC105374102 - +105374103 LOC105374103 - +105374104 LINC02021 HGNC:HGNC:52856 +105374105 LINC02014 HGNC:HGNC:52849 +105374106 LOC105374106 - +105374107 LOC105374107 - +105374108 LOC105374108 - +105374110 LOC105374110 - +105374111 LOC105374111 - +105374113 LOC105374113 - +105374114 LOC105374114 - +105374115 LOC105374115 - +105374116 LOC105374116 - +105374117 LOC105374117 - +105374118 LOC105374118 - +105374119 LINC02004 HGNC:HGNC:52838 +105374120 LOC105374120 - +105374121 LOC105374121 - +105374122 LOC105374122 - +105374123 LOC105374123 - +105374124 LOC105374124 - +105374126 LOC105374126 - +105374127 LOC105374127 - +105374128 LOC105374128 - +105374129 LOC105374129 - +105374132 LOC105374132 - +105374134 LOC105374134 - +105374136 LOC105374136 - +105374137 LOC105374137 - +105374138 LOC105374138 - +105374139 LOC105374139 - +105374140 LOC105374140 - +105374141 LOC105374141 - +105374142 LOC105374142 - +105374143 LOC105374143 - +105374144 LOC105374144 - +105374145 LOC105374145 - +105374146 LINC02045 HGNC:HGNC:52885 +105374147 LOC105374147 - +105374148 LOC105374148 - +105374149 LINC02046 HGNC:HGNC:52886 +105374150 LOC105374150 - +105374151 LOC105374151 - +105374152 LOC105374152 - +105374153 LOC105374153 - +105374154 LOC105374154 - +105374155 LOC105374155 - +105374157 LOC105374157 - +105374158 LINC02066 HGNC:HGNC:52911 +105374159 LOC105374159 - +105374160 LOC105374160 - +105374162 LOC105374162 - +105374163 LOC105374163 - +105374164 LOC105374164 - +105374165 LINC02006 HGNC:HGNC:52842 +105374166 LOC105374166 - +105374167 LOC105374167 - +105374170 LOC105374170 - +105374171 LOC105374171 Ensembl:ENSG00000243953 +105374172 LOC105374172 - +105374174 LOC105374174 - +105374177 LINC02029 HGNC:HGNC:52863|Ensembl:ENSG00000241544 +105374179 LOC105374179 - +105374181 LOC105374181 - +105374186 LOC105374186 - +105374187 LOC105374187 - +105374188 LOC105374188 - +105374189 LOC105374189 - +105374190 LOC105374190 - +105374191 LOC105374191 - +105374192 LOC105374192 - +105374193 LOC105374193 - +105374194 LOC105374194 - +105374195 LOC105374195 - +105374196 LOC105374196 - +105374197 LOC105374197 - +105374200 LOC105374200 - +105374201 LINC01997 HGNC:HGNC:52831 +105374205 LOC105374205 Ensembl:ENSG00000241479 +105374206 LOC105374206 - +105374209 LOC105374209 - +105374211 LOC105374211 - +105374216 LOC105374216 - +105374217 LOC105374217 - +105374218 LOC105374218 - +105374219 LINC02068 HGNC:HGNC:52914 +105374220 LOC105374220 - +105374221 LOC105374221 - +105374224 LOC105374224 - +105374225 LOC105374225 - +105374226 LOC105374226 - +105374229 LOC105374229 - +105374230 LOC105374230 - +105374234 LOC105374234 - +105374235 LOC105374235 - +105374238 LOC105374238 - +105374240 LOC105374240 - +105374242 LOC105374242 - +105374243 LOC105374243 - +105374244 LINC01995 HGNC:HGNC:52828|Ensembl:ENSG00000244247 +105374245 LOC105374245 - +105374246 LOC105374246 - +105374247 LOC105374247 - +105374248 LOC105374248 - +105374249 LOC105374249 - +105374250 LINC02054 HGNC:HGNC:52894 +105374251 LINC01839 HGNC:HGNC:41330 +105374252 LOC105374252 - +105374253 LOC105374253 - +105374254 LOC105374254 - +105374257 LOC105374257 - +105374258 LOC105374258 - +105374259 LOC105374259 - +105374260 LOC105374260 - +105374261 LINC02041 HGNC:HGNC:52881 +105374262 LOC105374262 - +105374263 LOC105374263 - +105374264 LOC105374264 - +105374265 LOC105374265 - +105374266 LINC01991 HGNC:HGNC:52823 +105374270 LOC105374270 - +105374272 LINC02013 HGNC:HGNC:52848 +105374275 LOC105374275 - +105374276 LOC105374276 - +105374277 LOC105374277 - +105374280 LOC105374280 - +105374282 LOC105374282 - +105374283 LOC105374283 - +105374284 LOC105374284 - +105374285 LINC02038 HGNC:HGNC:52878 +105374286 LOC105374286 - +105374287 LOC105374287 - +105374288 LOC105374288 - +105374289 LINC02048 HGNC:HGNC:52888 +105374291 LOC105374291 - +105374292 LOC105374292 - +105374293 LINC01972 HGNC:HGNC:52798|Ensembl:ENSG00000230401 +105374294 LOC105374294 - +105374295 LOC105374295 - +105374296 LOC105374296 - +105374297 LOC105374297 - +105374298 LOC105374298 - +105374299 LOC105374299 - +105374300 LOC105374300 - +105374301 LOC105374301 - +105374303 LOC105374303 - +105374304 LOC105374304 - +105374306 LOC105374306 - +105374307 LOC105374307 - +105374308 LOC105374308 - +105374309 LOC105374309 - +105374310 LOC105374310 - +105374312 LOC105374312 - +105374313 LOC105374313 - +105374314 LOC105374314 - +105374317 LOC105374317 - +105374318 LOC105374318 - +105374320 LOC105374320 - +105374322 LINC01830 HGNC:HGNC:52636 +105374323 LOC105374323 - +105374325 LOC105374325 - +105374328 LOC105374328 Ensembl:ENSG00000232642 +105374329 LOC105374329 - +105374332 LOC105374332 - +105374333 LOC105374333 - +105374334 LOC105374334 - +105374336 LOC105374336 - +105374337 LOC105374337 - +105374338 LOC105374338 - +105374339 LOC105374339 - +105374340 LOC105374340 - +105374341 LOC105374341 - +105374343 LOC105374343 - +105374344 LOC105374344 Ensembl:ENSG00000251652 +105374346 LOC105374346 - +105374347 LOC105374347 - +105374348 LOC105374348 - +105374349 LOC105374349 - +105374350 LOC105374350 - +105374352 LOC105374352 - +105374353 LOC105374353 - +105374354 LOC105374354 - +105374355 LOC105374355 - +105374357 LOC105374357 - +105374358 LOC105374358 - +105374359 LOC105374359 - +105374362 LOC105374362 - +105374363 LOC105374363 - +105374364 LOC105374364 - +105374365 LOC105374365 - +105374366 LINC02482 HGNC:HGNC:53458|Ensembl:ENSG00000251580 +105374367 LOC105374367 - +105374368 LOC105374368 - +105374369 LOC105374369 - +105374370 LOC105374370 - +105374371 LOC105374371 - +105374373 LOC105374373 - +105374374 LINC02517 HGNC:HGNC:53506|Ensembl:ENSG00000248986 +105374376 LOC105374376 - +105374377 LOC105374377 - +105374378 LOC105374378 - +105374381 LOC105374381 - +105374382 LOC105374382 - +105374383 LOC105374383 - +105374384 LOC105374384 - +105374385 LOC105374385 - +105374386 LOC105374386 - +105374387 LOC105374387 - +105374389 LOC105374389 - +105374391 LOC105374391 - +105374392 LOC105374392 - +105374394 LINC02484 HGNC:HGNC:53459 +105374396 LOC105374396 - +105374397 LOC105374397 - +105374399 LOC105374399 - +105374400 LINC02505 HGNC:HGNC:53494 +105374402 LOC105374402 - +105374404 LOC105374404 - +105374406 LOC105374406 - +105374407 LOC105374407 - +105374408 LOC105374408 - +105374409 LOC105374409 - +105374410 LINC02513 HGNC:HGNC:53502 +105374411 LINC02278 HGNC:HGNC:53194 +105374412 LOC105374412 - +105374413 LOC105374413 - +105374414 LOC105374414 - +105374418 LOC105374418 - +105374419 LOC105374419 - +105374421 LOC105374421 - +105374423 LOC105374423 - +105374425 LOC105374425 - +105374426 LOC105374426 - +105374428 LOC105374428 Ensembl:ENSG00000250781 +105374430 LOC105374430 - +105374431 LOC105374431 - +105374432 LOC105374432 - +105374433 LOC105374433 - +105374434 LOC105374434 - +105374435 LOC105374435 - +105374436 LINC02383 HGNC:HGNC:53306|Ensembl:ENSG00000248143 +105374438 LOC105374438 - +105374439 LOC105374439 - +105374440 LOC105374440 - +105374441 LOC105374441 - +105374442 LOC105374442 - +105374443 LOC105374443 - +105374444 LOC105374444 - +105374445 LOC105374445 - +105374447 LOC105374447 - +105374449 LINC01946 HGNC:HGNC:52770 +105374453 LOC105374453 - +105374454 LOC105374454 - +105374455 LOC105374455 - +105374456 LOC105374456 - +105374457 LOC105374457 - +105374458 LOC105374458 - +105374459 LOC105374459 - +105374461 LOC105374461 Ensembl:ENSG00000237320 +105374464 LOC105374464 - +105374465 LOC105374465 - +105374466 LOC105374466 - +105374467 LOC105374467 - +105374468 LOC105374468 - +105374470 LOC105374470 - +105374471 LOC105374471 - +105374473 LOC105374473 - +105374474 LOC105374474 - +105374475 LOC105374475 - +105374476 LOC105374476 - +105374478 LOC105374478 - +105374479 LOC105374479 - +105374480 LOC105374480 - +105374481 LOC105374481 - +105374482 LOC105374482 - +105374483 LOC105374483 - +105374484 LINC02360 HGNC:HGNC:53282 +105374487 LOC105374487 - +105374488 LOC105374488 - +105374489 LOC105374489 - +105374490 LOC105374490 - +105374491 LOC105374491 - +105374492 LOC105374492 - +105374493 LOC105374493 - +105374494 LOC105374494 - +105374495 LOC105374495 - +105374496 LOC105374496 - +105374497 LOC105374497 - +105374498 LOC105374498 - +105374501 LOC105374501 - +105374502 LOC105374502 - +105374505 LOC105374505 - +105374506 LOC105374506 - +105374507 LOC105374507 - +105374510 LOC105374510 - +105374511 LOC105374511 - +105374513 LOC105374513 - +105374514 LOC105374514 - +105374515 LOC105374515 - +105374516 LOC105374516 Ensembl:ENSG00000250092 +105374517 LOC105374517 - +105374519 LOC105374519 - +105374520 LOC105374520 - +105374521 LOC105374521 - +105374523 LOC105374523 - +105374524 LOC105374524 Ensembl:ENSG00000248837 +105374525 LOC105374525 - +105374527 LOC105374527 - +105374528 LOC105374528 - +105374531 LOC105374531 - +105374533 LOC105374533 - +105374534 LOC105374534 - +105374535 LOC105374535 - +105374536 LOC105374536 - +105374537 LOC105374537 - +105374538 LOC105374538 - +105374540 LINC02357 HGNC:HGNC:53279|Ensembl:ENSG00000283314 +105374541 LOC105374541 - +105374542 LOC105374542 - +105374545 LOC105374545 - +105374546 LOC105374546 - +105374547 LOC105374547 - +105374548 LOC105374548 - +105374549 LOC105374549 - +105374550 LOC105374550 - +105374552 LOC105374552 - +105374553 LOC105374553 - +105374555 LOC105374555 - +105374556 LOC105374556 - +105374557 LOC105374557 - +105374558 LOC105374558 - +105374559 LOC105374559 - +105374561 LINC02472 HGNC:HGNC:53411 +105374562 LOC105374562 - +105374564 LOC105374564 - +105374565 LINC02501 HGNC:HGNC:53489 +105374566 LOC105374566 - +105374567 LOC105374567 - +105374568 LOC105374568 - +105374570 LOC105374570 - +105374571 LOC105374571 - +105374573 LOC105374573 - +105374576 LOC105374576 - +105374577 LOC105374577 - +105374580 LOC105374580 Ensembl:ENSG00000228481 +105374581 LOC105374581 - +105374582 LINC01820 HGNC:HGNC:52625 +105374583 LOC105374583 - +105374584 LOC105374584 - +105374585 LOC105374585 - +105374588 LOC105374588 - +105374589 LOC105374589 - +105374590 LOC105374590 - +105374591 LOC105374591 - +105374592 LOC105374592 - +105374593 LOC105374593 - +105374594 LOC105374594 - +105374595 LOC105374595 - +105374596 LINC01867 HGNC:HGNC:52687|Ensembl:ENSG00000225444 +105374597 LOC105374597 - +105374598 LOC105374598 - +105374600 LOC105374600 - +105374601 LOC105374601 - +105374602 LOC105374602 - +105374604 LOC105374604 - +105374606 LOC105374606 - +105374607 LOC105374607 - +105374608 LOC105374608 - +105374610 LOC105374610 - +105374612 LOC105374612 - 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LOC105374657 - +105374658 LINC02220 HGNC:HGNC:53087 +105374659 LOC105374659 - +105374660 LOC105374660 - +105374661 LOC105374661 - +105374662 LOC105374662 - +105374663 LOC105374663 - +105374664 LOC105374664 - +105374666 LOC105374666 - +105374667 LOC105374667 - +105374668 LOC105374668 - +105374669 LOC105374669 - +105374671 LOC105374671 - +105374672 LOC105374672 - +105374673 LOC105374673 - +105374674 LOC105374674 - +105374676 LINC02241 HGNC:HGNC:53126 +105374677 LINC02146 HGNC:HGNC:53006 +105374678 LOC105374678 - +105374680 LOC105374680 - +105374681 LOC105374681 - +105374682 LOC105374682 - +105374683 LOC105374683 - +105374685 LOC105374685 - +105374686 LOC105374686 - +105374687 LOC105374687 - +105374688 LOC105374688 - +105374689 LOC105374689 - +105374690 LOC105374690 - +105374693 LINC02211 HGNC:HGNC:53078 +105374694 LINC02228 HGNC:HGNC:53097 +105374695 LOC105374695 - +105374696 LOC105374696 - +105374697 LOC105374697 - +105374698 LINC02103 HGNC:HGNC:52958|Ensembl:ENSG00000249785 +105374699 LOC105374699 - +105374701 LOC105374701 - +105374702 LOC105374702 - +105374703 LOC105374703 - +105374704 LOC105374704 - +105374705 LOC105374705 - +105374706 LOC105374706 - +105374707 LOC105374707 - +105374709 LOC105374709 - +105374711 LOC105374711 - +105374714 LINC02061 HGNC:HGNC:52906 +105374715 LOC105374715 - +105374716 LINC02160 HGNC:HGNC:53021 +105374717 LOC105374717 - +105374719 LOC105374719 - +105374721 LOC105374721 - +105374723 LOC105374723 - +105374724 LOC105374724 - +105374725 LOC105374725 - +105374726 LOC105374726 - +105374727 LOC105374727 - +105374728 LINC02117 HGNC:HGNC:52972 +105374729 LINC02110 HGNC:HGNC:52965|Ensembl:ENSG00000251518 +105374730 LOC105374730 - +105374731 LINC02107 HGNC:HGNC:52962|Ensembl:ENSG00000250003 +105374732 LOC105374732 - +105374733 LOC105374733 - +105374735 LOC105374735 - +105374736 LOC105374736 - +105374737 LOC105374737 - +105374738 LOC105374738 - +105374739 LOC105374739 - +105374740 LOC105374740 - +105374744 LINC01795 HGNC:HGNC:52585 +105374745 LOC105374745 - +105374746 LOC105374746 - +105374748 LOC105374748 - +105374749 LOC105374749 - +105374754 LOC105374754 - +105374758 LOC105374758 - +105374759 LOC105374759 - +105374760 LOC105374760 - +105374761 LOC105374761 - +105374764 LOC105374764 - +105374768 LOC105374768 - +105374769 LOC105374769 - +105374771 LOC105374771 - +105374772 LOC105374772 - +105374773 LOC105374773 - +105374774 LINC01805 HGNC:HGNC:52597 +105374775 LOC105374775 - +105374776 LOC105374776 - +105374777 LOC105374777 - +105374778 LOC105374778 - +105374779 LOC105374779 - +105374780 LOC105374780 - +105374781 LOC105374781 - +105374785 LOC105374785 - +105374786 LOC105374786 - +105374789 LOC105374789 - +105374790 LOC105374790 - +105374791 LINC01890 HGNC:HGNC:52709|Ensembl:ENSG00000228329 +105374792 LOC105374792 - +105374793 LOC105374793 - +105374794 LOC105374794 - +105374795 LOC105374795 - +105374796 LOC105374796 - +105374797 LOC105374797 - +105374798 LOC105374798 - +105374800 LOC105374800 - +105374802 LOC105374802 - 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LOC105374845 - +105374846 LOC105374846 - +105374847 LINC01955 HGNC:HGNC:52780 +105374848 LOC105374848 - +105374849 LOC105374849 - +105374850 LOC105374850 - +105374851 LOC105374851 - +105374852 LOC105374852 - +105374853 LOC105374853 - +105374854 LOC105374854 - +105374855 LOC105374855 - +105374857 LOC105374857 - +105374858 LOC105374858 - +105374859 LOC105374859 - +105374862 LOC105374862 - +105374865 LOC105374865 - +105374866 LOC105374866 - +105374868 LOC105374868 - +105374869 LOC105374869 - +105374870 LOC105374870 - +105374873 LOC105374873 - +105374875 LOC105374875 - +105374879 LOC105374879 - +105374880 LOC105374880 - +105374882 LOC105374882 - +105374883 LOC105374883 - +105374885 LINC02521 HGNC:HGNC:53560 +105374887 LOC105374887 - +105374888 LOC105374888 - +105374889 LOC105374889 - +105374890 LOC105374890 - +105374893 LOC105374893 - +105374894 LOC105374894 - +105374895 LINC02533 HGNC:HGNC:53566 +105374897 LOC105374897 - +105374898 LOC105374898 - +105374901 LOC105374901 - +105374902 LOC105374902 - +105374903 LOC105374903 - +105374904 LOC105374904 - +105374906 LOC105374906 - +105374907 LOC105374907 - +105374910 LOC105374910 - +105374911 LOC105374911 - +105374912 LOC105374912 - +105374913 LOC105374913 - +105374914 LOC105374914 - +105374917 LOC105374917 - +105374918 LOC105374918 - +105374919 LOC105374919 - +105374920 LOC105374920 - +105374921 LOC105374921 - +105374923 LOC105374923 - +105374924 LOC105374924 - +105374925 LOC105374925 - +105374927 LOC105374927 - +105374928 LOC105374928 - +105374929 LOC105374929 - +105374931 LOC105374931 - +105374933 LOC105374933 - +105374934 LOC105374934 - +105374935 LOC105374935 - +105374936 LOC105374936 - +105374937 LOC105374937 - +105374938 LOC105374938 - +105374939 LOC105374939 - +105374940 LOC105374940 - +105374942 LOC105374942 - +105374943 LOC105374943 - +105374944 LOC105374944 - +105374945 LOC105374945 - +105374946 LOC105374946 - +105374947 LOC105374947 - +105374948 LOC105374948 - +105374949 LOC105374949 - +105374951 LOC105374951 - +105374952 LOC105374952 Ensembl:ENSG00000272269 +105374953 LOC105374953 - +105374955 LOC105374955 - +105374956 MIR548A1HG HGNC:HGNC:53539 +105374957 LOC105374957 - +105374958 LOC105374958 - +105374959 LOC105374959 - +105374960 LOC105374960 - +105374961 LOC105374961 - +105374963 LOC105374963 - +105374965 LOC105374965 - +105374966 LOC105374966 - +105374968 LOC105374968 - +105374970 LOC105374970 - +105374971 LOC105374971 - +105374972 LOC105374972 - +105374973 LOC105374973 - +105374974 LOC105374974 - +105374975 LOC105374975 - +105374976 LOC105374976 - +105374978 LOC105374978 - +105374981 LOC105374981 - +105374985 LOC105374985 - +105374986 LOC105374986 - +105374988 LOC105374988 - +105374989 LOC105374989 Ensembl:ENSG00000275846 +105374990 LOC105374990 - +105374991 LOC105374991 - +105374992 LOC105374992 - +105374995 LOC105374995 - +105374996 LOC105374996 - +105374997 LOC105374997 - +105374998 LOC105374998 - +105375001 LOC105375001 - +105375002 LOC105375002 - +105375003 LOC105375003 - 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LOC105375051 - +105375052 LOC105375052 - +105375053 LOC105375053 - +105375055 LOC105375055 - +105375056 LOC105375056 - +105375059 LOC105375059 - +105375060 LOC105375060 - +105375061 LOC105375061 - +105375063 LOC105375063 - +105375064 LOC105375064 - +105375065 LOC105375065 - +105375067 LOC105375067 - +105375068 LOC105375068 - +105375069 LOC105375069 - +105375070 LOC105375070 - +105375072 LOC105375072 - +105375074 LOC105375074 - +105375075 LOC105375075 - +105375077 RUNX2-AS1 HGNC:HGNC:53512 +105375078 LOC105375078 - +105375079 LOC105375079 - +105375080 LOC105375080 - +105375081 LOC105375081 - +105375082 LOC105375082 - +105375084 LOC105375084 - +105375085 LOC105375085 - +105375087 LOC105375087 - +105375088 LOC105375088 - +105375091 LOC105375091 - +105375092 LOC105375092 - +105375095 LOC105375095 Ensembl:ENSG00000249379 +105375097 LOC105375097 - +105375098 LOC105375098 - +105375100 LOC105375100 - +105375101 LOC105375101 - +105375102 LOC105375102 - +105375103 LOC105375103 - +105375106 LOC105375106 - +105375107 LOC105375107 - +105375111 LOC105375111 - +105375112 LOC105375112 - +105375113 LOC105375113 - +105375114 LOC105375114 - +105375115 LOC105375115 Ensembl:ENSG00000239715 +105375116 LOC105375116 - +105375118 LOC105375118 - +105375119 LOC105375119 - +105375120 LOC105375120 - +105375122 LOC105375122 - +105375123 LOC105375123 - +105375124 LOC105375124 - +105375126 LOC105375126 - +105375127 LOC105375127 - +105375128 LOC105375128 - +105375130 LOC105375130 - +105375131 LOC105375131 - +105375132 LOC105375132 - +105375133 LOC105375133 - +105375134 LOC105375134 - +105375138 LOC105375138 - +105375142 LOC105375142 - +105375144 LOC105375144 - +105375145 LOC105375145 - +105375146 LOC105375146 - +105375147 LOC105375147 - +105375148 LOC105375148 - +105375149 LOC105375149 - +105375150 LOC105375150 - +105375151 LOC105375151 - +105375153 LOC105375153 - +105375154 LOC105375154 - +105375155 LOC105375155 - +105375156 LOC105375156 - +105375157 LOC105375157 - +105375158 LOC105375158 - 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LOC105375259 - +105375260 LOC105375260 - +105375261 LINC01952 HGNC:HGNC:52775 +105375262 LOC105375262 - +105375264 LOC105375264 - +105375265 LOC105375265 - +105375266 LOC105375266 Ensembl:ENSG00000230680 +105375267 LOC105375267 - +105375268 LOC105375268 - +105375270 LOC105375270 - +105375271 LOC105375271 - +105375272 LOC105375272 - +105375273 LOC105375273 - +105375277 LOC105375277 - +105375278 LOC105375278 - +105375282 LOC105375282 - +105375283 GS1-278J22.2 - +105375284 LOC105375284 - +105375287 LOC105375287 - +105375288 LOC105375288 - +105375289 LOC105375289 - +105375291 LOC105375291 - +105375292 LOC105375292 - +105375294 LOC105375294 - +105375295 LOC105375295 - +105375296 LOC105375296 - +105375297 LOC105375297 Ensembl:ENSG00000234089 +105375298 LOC105375298 - +105375299 LOC105375299 - +105375300 LOC105375300 - +105375301 LOC105375301 - +105375302 LOC105375302 - +105375303 LOC105375303 - +105375304 LOC105375304 Ensembl:ENSG00000225792 +105375307 LOC105375307 - +105375308 LOC105375308 - +105375309 LOC105375309 - +105375310 LOC105375310 - +105375311 LOC105375311 - +105375313 LOC105375313 - +105375314 LOC105375314 - +105375315 LOC105375315 - +105375317 LOC105375317 - +105375318 LOC105375318 - +105375319 LOC105375319 - +105375321 LOC105375321 - +105375322 LOC105375322 - +105375323 LOC105375323 - +105375324 LOC105375324 - +105375326 LOC105375326 - +105375328 LOC105375328 - +105375329 LOC105375329 - +105375330 LOC105375330 - +105375333 LOC105375333 - +105375334 LOC105375334 - +105375335 LOC105375335 - +105375336 LOC105375336 - +105375337 LOC105375337 - +105375340 LOC105375340 - +105375341 LOC105375341 - +105375342 LOC105375342 Ensembl:ENSG00000233689 +105375343 LOC105375343 - +105375344 LOC105375344 - +105375345 LOC105375345 - +105375346 LOC105375346 - +105375347 LOC105375347 - +105375350 LOC105375350 - +105375352 LOC105375352 - +105375355 UPK3B MIM:611887|HGNC:HGNC:21444|Ensembl:ENSG00000243566|Vega:OTTHUMG00000149929 +105375356 LOC105375356 - +105375358 LOC105375358 - 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LOC105376342 - +105376344 LOC105376344 - +105376345 LOC105376345 - +105376346 LOC105376346 - +105376348 LOC105376348 - +105376349 LOC105376349 - +105376350 LOC105376350 - +105376351 LOC105376351 - +105376352 LOC105376352 - +105376353 LOC105376353 - +105376354 LOC105376354 - +105376356 LOC105376356 - +105376357 LOC105376357 - +105376358 LOC105376358 - +105376360 LOC105376360 - +105376361 LOC105376361 - +105376363 LOC105376363 - +105376364 LOC105376364 - +105376365 LOC105376365 Ensembl:ENSG00000230573 +105376367 LOC105376367 - +105376368 LOC105376368 - +105376369 LOC105376369 - +105376370 LOC105376370 - +105376371 LOC105376371 - +105376372 LOC105376372 - +105376373 LOC105376373 - +105376374 LOC105376374 - +105376375 LOC105376375 - +105376380 LOC105376380 - +105376381 LOC105376381 - +105376382 LOC105376382 Ensembl:ENSG00000242147 +105376383 LOC105376383 - +105376384 LOC105376384 - +105376386 LOC105376386 - +105376387 LOC105376387 - +105376388 LOC105376388 - +105376390 LOC105376390 - 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LOC105376484 - +105376485 LOC105376485 - +105376486 LOC105376486 - +105376488 LOC105376488 - +105376489 LOC105376489 - +105376490 LOC105376490 Ensembl:ENSG00000226412 +105376491 LOC105376491 - +105376493 LOC105376493 - +105376494 LOC105376494 - +105376495 LOC105376495 - +105376496 LOC105376496 - +105376497 LOC105376497 - +105376498 LOC105376498 - +105376499 LOC105376499 - +105376500 LOC105376500 - +105376504 LOC105376504 - +105376505 LOC105376505 - +105376506 LOC105376506 - +105376507 LOC105376507 - +105376508 LOC105376508 - +105376509 LOC105376509 - +105376511 LOC105376511 - +105376512 LOC105376512 - +105376513 LOC105376513 - +105376514 LOC105376514 - +105376516 LOC105376516 - +105376517 LOC105376517 - +105376520 LOC105376520 - +105376525 LOC105376525 - +105376526 LOC105376526 - +105376527 LOC105376527 Ensembl:ENSG00000228661 +105376528 LOC105376528 - +105376532 LOC105376532 - +105376533 LOC105376533 - +105376535 LOC105376535 - +105376536 LOC105376536 - +105376539 LOC105376539 - 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Ensembl:ENSG00000254594 +105376595 LOC105376595 - +105376596 LOC105376596 - +105376598 LOC105376598 - +105376599 LOC105376599 Ensembl:ENSG00000254819 +105376600 LOC105376600 - +105376601 LOC105376601 - +105376602 LOC105376602 - +105376603 LOC105376603 - +105376604 LOC105376604 - +105376605 LOC105376605 - +105376606 LINC02546 HGNC:HGNC:53581|Ensembl:ENSG00000255117 +105376607 LOC105376607 - +105376609 LOC105376609 Ensembl:ENSG00000254489 +105376611 LOC105376611 - +105376613 LOC105376613 - +105376615 LOC105376615 - +105376617 LOC105376617 Ensembl:ENSG00000255202 +105376619 LOC105376619 - +105376620 LOC105376620 - +105376621 LOC105376621 - +105376622 LOC105376622 - +105376623 LOC105376623 - +105376624 LOC105376624 - +105376625 LOC105376625 - +105376626 LOC105376626 - +105376627 LOC105376627 - +105376631 LOC105376631 - +105376632 LOC105376632 - +105376633 LOC105376633 Ensembl:ENSG00000254516 +105376634 LOC105376634 - +105376635 LOC105376635 - +105376636 LOC105376636 - +105376637 LOC105376637 - +105376639 LOC105376639 - +105376640 LOC105376640 - +105376641 LOC105376641 - +105376642 LOC105376642 - +105376644 LOC105376644 - +105376645 LOC105376645 - +105376646 LOC105376646 - +105376647 LOC105376647 - +105376649 LOC105376649 - +105376650 LOC105376650 - +105376652 LOC105376652 - +105376654 LOC105376654 - +105376655 LOC105376655 - +105376656 LOC105376656 - +105376658 LOC105376658 - +105376661 LOC105376661 - +105376662 LOC105376662 - +105376666 LOC105376666 - +105376668 LOC105376668 - +105376670 LOC105376670 - +105376671 LOC105376671 Ensembl:ENSG00000254862 +105376672 LINC01345 HGNC:HGNC:50564|Ensembl:ENSG00000226374 +105376673 LOC105376673 - +105376674 LOC105376674 - +105376675 LOC105376675 - +105376678 LOC105376678 - +105376679 LINC01646 HGNC:HGNC:52433 +105376680 LOC105376680 - +105376681 LOC105376681 - +105376682 LOC105376682 - +105376684 LOC105376684 - +105376686 LOC105376686 - +105376687 LOC105376687 - +105376689 LOC105376689 - +105376691 LOC105376691 - 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+105376760 LOC105376760 - +105376762 LOC105376762 - +105376763 LOC105376763 - +105376767 LOC105376767 - +105376772 LOC105376772 - +105376774 LOC105376774 - +105376775 LOC105376775 - +105376777 LOC105376777 - +105376778 LOC105376778 - +105376781 LOC105376781 - +105376786 LOC105376786 - +105376787 LOC105376787 - +105376789 LOC105376789 - +105376791 LOC105376791 - +105376794 LOC105376794 - +105376799 LOC105376799 - +105376805 LOC105376805 Ensembl:ENSG00000238142 +105376806 LOC105376806 - +105376808 LOC105376808 - +105376809 LOC105376809 - +105376810 LOC105376810 - +105376812 LOC105376812 - +105376814 LOC105376814 - +105376815 LOC105376815 - +105376817 LOC105376817 - +105376818 LOC105376818 - +105376819 LOC105376819 - +105376823 LOC105376823 - +105376825 LOC105376825 - +105376826 LOC105376826 - +105376827 LINC01757 HGNC:HGNC:52546 +105376828 LOC105376828 - +105376829 LOC105376829 - +105376830 LOC105376830 - +105376832 LOC105376832 - +105376834 LOC105376834 - +105376836 LOC105376836 - +105376839 LOC105376839 - +105376841 LOC105376841 - +105376843 SNHG25 HGNC:HGNC:51534|Ensembl:ENSG00000266402 +105376844 LOC105376844 - +105376845 LOC105376845 - +105376850 LOC105376850 - +105376854 LINC01925 HGNC:HGNC:52745|Ensembl:ENSG00000264265 +105376856 LOC105376856 - +105376859 LOC105376859 - +105376860 LOC105376860 - +105376861 LOC105376861 - +105376863 LOC105376863 - +105376864 LOC105376864 - +105376866 LOC105376866 - +105376868 LOC105376868 - +105376871 LOC105376871 - +105376872 LOC105376872 - +105376873 LOC105376873 - +105376874 LOC105376874 - +105376875 LOC105376875 - +105376876 LOC105376876 - +105376878 LOC105376878 - +105376879 LOC105376879 - +105376882 LOC105376882 - +105376885 LOC105376885 - +105376886 LOC105376886 - +105376888 LOC105376888 - +105376890 LOC105376890 - +105376892 LOC105376892 - +105376898 LOC105376898 - +105376899 LOC105376899 - +105376901 LOC105376901 - +105376906 LOC105376906 - +105376910 LOC105376910 - +105376912 LOC105376912 - +105376914 LOC105376914 - +105376917 LOC105376917 - +105376921 LOC105376921 - +105376922 LOC105376922 - +105376923 LOC105376923 - +105376924 LOC105376924 - +105376926 LOC105376926 - +105376931 LOC105376931 - +105376933 LOC105376933 - +105376934 LOC105376934 - +105376936 LOC105376936 - +105376938 LOC105376938 - +105376939 LOC105376939 - +105376940 LOC105376940 - +105376941 LOC105376941 - +105376942 LOC105376942 - +105376943 LOC105376943 - +105376944 LOC105376944 - +105376945 LOC105376945 - +105376946 GRM7-AS2 HGNC:HGNC:40266|Ensembl:ENSG00000237665 +105376949 LOC105376949 - +105376950 LOC105376950 - +105376951 LOC105376951 - +105376952 LOC105376952 - +105376955 LINC02022 HGNC:HGNC:52857|Ensembl:ENSG00000232746 +105376956 LOC105376956 - +105376957 LOC105376957 - +105376958 LOC105376958 - +105376959 LOC105376959 - +105376960 LOC105376960 - +105376961 LOC105376961 - +105376963 LOC105376963 - +105376964 LOC105376964 - +105376972 LOC105376972 - +105376975 LOC105376975 - +105376976 LOC105376976 - +105376978 LOC105376978 - +105376980 LOC105376980 - +105376981 LOC105376981 - +105376982 LOC105376982 - +105376984 LOC105376984 - +105376985 LOC105376985 - +105376987 LOC105376987 - +105376988 LOC105376988 - +105376989 LOC105376989 - +105376991 LOC105376991 - +105376992 LINC01742 HGNC:HGNC:52530|Ensembl:ENSG00000275852 +105376993 LOC105376993 - +105376995 LOC105376995 - +105376996 LOC105376996 - +105376997 LOC105376997 - +105376998 LOC105376998 - +105377000 LOC105377000 - +105377001 LOC105377001 - +105377002 LOC105377002 - +105377003 LOC105377003 - +105377004 LOC105377004 - +105377005 LOC105377005 - +105377006 LINC02084 HGNC:HGNC:52934 +105377007 LINC01980 HGNC:HGNC:52808 +105377008 LOC105377008 - +105377009 LOC105377009 - +105377012 LOC105377012 - +105377013 LOC105377013 - +105377015 LOC105377015 - +105377016 LOC105377016 - +105377017 LOC105377017 - +105377018 LOC105377018 - +105377019 LOC105377019 - +105377021 LOC105377021 - +105377022 LOC105377022 - +105377023 LOC105377023 - +105377024 LOC105377024 - +105377029 LOC105377029 - +105377030 LOC105377030 - +105377031 LINC02033 HGNC:HGNC:52867 +105377033 LOC105377033 - +105377034 LOC105377034 - +105377035 LOC105377035 - +105377037 LOC105377037 - +105377038 LOC105377038 - +105377039 LOC105377039 - +105377043 LOC105377043 - +105377045 LOC105377045 - +105377046 LOC105377046 - +105377048 LOC105377048 - +105377051 LOC105377051 - +105377052 LOC105377052 - +105377054 LOC105377054 - +105377055 LOC105377055 - +105377056 LOC105377056 - +105377059 LOC105377059 - +105377061 LOC105377061 - +105377062 LOC105377062 - +105377063 LOC105377063 - +105377066 LOC105377066 - +105377067 LOC105377067 - +105377068 LINC02009 HGNC:HGNC:52845|Ensembl:ENSG00000283646 +105377070 LOC105377070 - +105377073 LOC105377073 - +105377074 LOC105377074 - +105377077 LOC105377077 - +105377079 LOC105377079 - +105377082 LOC105377082 - +105377083 LOC105377083 - +105377085 LOC105377085 - +105377086 LOC105377086 - +105377087 LOC105377087 - +105377088 LOC105377088 - +105377089 LOC105377089 - +105377090 LOC105377090 - +105377091 LOC105377091 - +105377094 LOC105377094 - +105377095 LOC105377095 - +105377096 LINC02017 HGNC:HGNC:52852 +105377097 LOC105377097 - +105377098 LINC02030 HGNC:HGNC:52864 +105377099 LOC105377099 - +105377100 LOC105377100 - +105377101 LOC105377101 - +105377102 LOC105377102 - +105377103 LOC105377103 - +105377104 LOC105377104 - +105377105 FLNB-AS1 HGNC:HGNC:40239|Ensembl:ENSG00000244161 +105377106 LOC105377106 - +105377108 FAM3D-AS1 HGNC:HGNC:41276|Ensembl:ENSG00000244383 +105377109 LOC105377109 - +105377110 LOC105377110 - +105377111 LOC105377111 - +105377112 LOC105377112 - +105377113 LOC105377113 - +105377114 LOC105377114 - +105377115 LOC105377115 - +105377116 LOC105377116 - +105377119 LOC105377119 - +105377121 LOC105377121 - +105377123 LOC105377123 - +105377124 LOC105377124 - +105377125 LOC105377125 - +105377127 LOC105377127 - +105377128 LOC105377128 - +105377130 LOC105377130 - +105377134 LOC105377134 - +105377135 LOC105377135 - +105377136 LOC105377136 - +105377137 LOC105377137 - +105377138 LINC01678 HGNC:HGNC:52466|Ensembl:ENSG00000225331 +105377139 LOC105377139 - +105377141 LOC105377141 - +105377142 LOC105377142 - +105377143 LOC105377143 - +105377144 LOC105377144 - +105377146 LOC105377146 - +105377148 LOC105377148 - +105377151 LOC105377151 - +105377152 LOC105377152 - +105377155 LOC105377155 - +105377156 LOC105377156 - +105377157 LOC105377157 - +105377158 LOC105377158 - +105377159 LOC105377159 - +105377160 LOC105377160 - +105377161 LOC105377161 - +105377162 LOC105377162 - +105377164 LOC105377164 - +105377165 LINC02005 HGNC:HGNC:52839 +105377166 LOC105377166 - +105377167 LOC105377167 - +105377168 LOC105377168 - +105377169 LOC105377169 - +105377171 LOC105377171 - +105377172 LINC02077 HGNC:HGNC:52925 +105377173 LOC105377173 - +105377174 LOC105377174 - +105377175 LINC02050 HGNC:HGNC:52890 +105377176 LOC105377176 - +105377177 LOC105377177 - +105377178 LOC105377178 - +105377179 LOC105377179 - +105377180 LINC02008 HGNC:HGNC:52844 +105377181 LOC105377181 - +105377182 LOC105377182 - +105377183 LOC105377183 - +105377186 LOC105377186 - +105377187 LOC105377187 - +105377188 LOC105377188 - +105377190 LOC105377190 - +105377191 LOC105377191 - +105377192 LINC02025 HGNC:HGNC:52860 +105377193 LOC105377193 - +105377196 LOC105377196 - +105377198 LOC105377198 - +105377199 LOC105377199 - +105377202 LOC105377202 - +105377203 LOC105377203 - +105377205 LOC105377205 - +105377207 LOC105377207 - +105377208 LOC105377208 - +105377209 LOC105377209 - +105377211 LOC105377211 - +105377212 LOC105377212 - +105377213 LOC105377213 Ensembl:ENSG00000214915 +105377217 LOC105377217 - +105377218 LOC105377218 - +105377219 LOC105377219 - +105377220 LOC105377220 - +105377223 LOC105377223 - +105377224 LOC105377224 - +105377225 LOC105377225 - +105377227 LOC105377227 - +105377229 LOC105377229 - +105377230 LOC105377230 - +105377231 LOC105377231 - +105377232 LOC105377232 - +105377234 LOC105377234 - +105377235 LOC105377235 - +105377236 LOC105377236 - +105377237 LOC105377237 - +105377238 LOC105377238 - +105377239 LOC105377239 - +105377240 REREP1Y HGNC:HGNC:38795 +105377241 LOC105377241 - +105377242 LOC105377242 - +105377243 REREP2Y HGNC:HGNC:38796 +105377244 LOC105377244 - +105377245 LOC105377245 Ensembl:ENSG00000249382 +105377246 LOC105377246 - +105377247 LINC02429 HGNC:HGNC:53360|Ensembl:ENSG00000251266 +105377248 LINC02496 HGNC:HGNC:53480 +105377249 LINC02271 HGNC:HGNC:53186 +105377253 LOC105377253 - +105377254 LOC105377254 - +105377255 LOC105377255 - +105377256 LOC105377256 - +105377258 LOC105377258 - +105377259 LOC105377259 - +105377260 LOC105377260 - +105377261 LOC105377261 - +105377262 LOC105377262 - +105377265 LOC105377265 - +105377267 LOC105377267 Ensembl:ENSG00000250696 +105377269 LOC105377269 - +105377270 LOC105377270 - +105377271 LOC105377271 - +105377272 LOC105377272 - +105377273 LOC105377273 - +105377275 LOC105377275 - +105377276 LOC105377276 - +105377277 LOC105377277 - +105377278 LOC105377278 - +105377280 LOC105377280 - +105377282 LOC105377282 - +105377283 LOC105377283 - +105377284 LOC105377284 - +105377285 LOC105377285 - +105377286 LOC105377286 - +105377289 LOC105377289 - +105377290 LOC105377290 - +105377291 LOC105377291 - +105377294 LOC105377294 - +105377295 LOC105377295 - +105377296 LOC105377296 - +105377297 LOC105377297 - +105377299 LOC105377299 - +105377300 LOC105377300 - +105377301 LINC02469 HGNC:HGNC:53408 +105377302 LOC105377302 - +105377303 LOC105377303 - +105377305 LOC105377305 - +105377306 LOC105377306 - +105377307 LOC105377307 Ensembl:ENSG00000284516 +105377308 LOC105377308 - +105377310 LOC105377310 - +105377313 LOC105377313 - +105377315 LOC105377315 - +105377319 LOC105377319 - +105377320 LOC105377320 - +105377321 LOC105377321 - +105377322 LOC105377322 - +105377323 LOC105377323 - +105377324 LOC105377324 - +105377325 LOC105377325 - +105377326 LOC105377326 - +105377327 LOC105377327 - +105377328 LOC105377328 - +105377329 LOC105377329 - +105377331 LOC105377331 - +105377335 LOC105377335 - +105377337 LOC105377337 - +105377338 LINC02267 HGNC:HGNC:53181 +105377340 LOC105377340 - +105377342 LOC105377342 - +105377343 LOC105377343 - +105377345 LOC105377345 - +105377346 LOC105377346 - +105377347 LOC105377347 - +105377348 LOC105377348 Ensembl:ENSG00000246560 +105377349 LINC02503 HGNC:HGNC:53492 +105377350 LOC105377350 - +105377351 LOC105377351 - +105377352 LOC105377352 - +105377355 LINC02173 HGNC:HGNC:53035 +105377356 LOC105377356 - +105377357 LOC105377357 - +105377358 LOC105377358 - +105377359 LOC105377359 - +105377362 LOC105377362 - +105377363 LOC105377363 - +105377364 LOC105377364 - +105377365 LOC105377365 - +105377366 LOC105377366 - +105377367 LOC105377367 - +105377369 LOC105377369 - +105377370 LOC105377370 - +105377372 LOC105377372 - +105377373 LOC105377373 - +105377374 LOC105377374 - +105377375 LOC105377375 - +105377376 LOC105377376 - +105377378 LOC105377378 - +105377379 LOC105377379 - +105377380 LOC105377380 - +105377382 LOC105377382 - +105377383 LOC105377383 - +105377384 LOC105377384 - +105377385 LOC105377385 - +105377387 LOC105377387 - +105377388 LOC105377388 - +105377389 LINC02262 HGNC:HGNC:53174 +105377390 LINC02263 HGNC:HGNC:53175|Ensembl:ENSG00000228358 +105377391 LINC02264 HGNC:HGNC:53176|Ensembl:ENSG00000229565 +105377392 LOC105377392 - +105377393 LOC105377393 - +105377394 LOC105377394 - +105377395 LOC105377395 - +105377396 LOC105377396 - +105377397 LOC105377397 - +105377399 LOC105377399 - +105377400 LOC105377400 - +105377401 LOC105377401 - +105377402 LOC105377402 - +105377404 LOC105377404 - +105377405 LOC105377405 - +105377406 LOC105377406 - +105377407 LOC105377407 - +105377408 LOC105377408 - +105377409 LOC105377409 - +105377410 LOC105377410 - +105377411 LOC105377411 - +105377412 LOC105377412 - +105377413 LOC105377413 - +105377414 LOC105377414 - +105377416 LOC105377416 - +105377417 LOC105377417 - +105377418 LOC105377418 - +105377420 LINC02479 HGNC:HGNC:53453 +105377422 LOC105377422 - +105377423 LOC105377423 - +105377424 LINC02377 HGNC:HGNC:53300 +105377425 LOC105377425 - +105377428 LOC105377428 - +105377430 LOC105377430 - +105377431 LOC105377431 - +105377432 LOC105377432 - +105377434 LINC02462 HGNC:HGNC:53399 +105377436 LOC105377436 - +105377437 LOC105377437 - +105377438 LOC105377438 - +105377439 LINC02485 HGNC:HGNC:53460|Ensembl:ENSG00000248456 +105377441 LINC02511 HGNC:HGNC:53500 +105377442 LOC105377442 - +105377443 LINC02172 HGNC:HGNC:53034|Ensembl:ENSG00000251632 +105377444 LOC105377444 - +105377445 LOC105377445 - +105377446 LINC00498 HGNC:HGNC:43435 +105377447 LOC105377447 - +105377448 LOC105377448 Ensembl:ENSG00000250195 +105377449 LOC105377449 - +105377451 LOC105377451 - +105377452 LOC105377452 - +105377453 LOC105377453 - +105377456 LINC02276 HGNC:HGNC:53192 +105377457 LOC105377457 - +105377458 LOC105377458 - +105377459 LOC105377459 - +105377460 LOC105377460 - +105377461 LOC105377461 - +105377462 LOC105377462 - +105377463 LOC105377463 - +105377465 LOC105377465 - +105377466 LINC02266 HGNC:HGNC:53180 +105377467 LINC02491 HGNC:HGNC:53475 +105377468 LOC105377468 - +105377469 LOC105377469 - +105377470 LOC105377470 - +105377472 LOC105377472 - +105377473 LOC105377473 - +105377474 LOC105377474 - +105377475 LOC105377475 - +105377476 LOC105377476 - +105377477 LINC02507 HGNC:HGNC:53496 +105377478 LOC105377478 - +105377479 LOC105377479 - +105377480 LOC105377480 Ensembl:ENSG00000249317 +105377481 LOC105377481 - +105377483 LOC105377483 - +105377485 LOC105377485 - +105377486 LOC105377486 - +105377488 LOC105377488 - +105377489 LOC105377489 - +105377490 LOC105377490 - +105377492 LOC105377492 - +105377495 LOC105377495 - +105377496 LOC105377496 - +105377498 LOC105377498 - +105377499 LOC105377499 - +105377500 LOC105377500 - +105377501 LOC105377501 - +105377502 LOC105377502 - +105377503 LOC105377503 - +105377504 LOC105377504 - +105377505 LOC105377505 - +105377506 LOC105377506 - +105377507 LOC105377507 - +105377508 LOC105377508 - +105377509 LOC105377509 - +105377510 LOC105377510 - +105377512 LINC02477 HGNC:HGNC:53425 +105377513 LOC105377513 - +105377514 LOC105377514 - +105377515 LOC105377515 - +105377516 LOC105377516 - +105377517 LOC105377517 - +105377519 LOC105377519 - +105377520 LOC105377520 - +105377521 LOC105377521 - +105377523 LOC105377523 - +105377524 LOC105377524 - +105377527 LOC105377527 - +105377529 LOC105377529 - +105377530 LOC105377530 - +105377532 APOBEC3AP1 HGNC:HGNC:43835 +105377534 LOC105377534 - +105377535 LOC105377535 - +105377536 LINC02174 HGNC:HGNC:53037|Ensembl:ENSG00000249297 +105377537 LOC105377537 - +105377540 LOC105377540 - +105377541 LOC105377541 - +105377543 LOC105377543 - +105377544 LOC105377544 - +105377546 LOC105377546 - +105377547 LOC105377547 - +105377548 LOC105377548 - +105377549 LOC105377549 - +105377551 LOC105377551 - +105377552 LOC105377552 - +105377555 LOC105377555 - +105377556 LINC02509 HGNC:HGNC:53498 +105377557 LOC105377557 - +105377558 LOC105377558 - +105377559 LOC105377559 - +105377560 LOC105377560 - +105377561 LOC105377561 - +105377562 LOC105377562 - +105377563 LOC105377563 - +105377564 LOC105377564 - +105377565 LOC105377565 - +105377567 LOC105377567 - +105377568 LOC105377568 - +105377570 LOC105377570 - +105377571 LOC105377571 - +105377572 LOC105377572 - +105377573 TEMN3-AS1 HGNC:HGNC:53456 +105377576 LOC105377576 - +105377577 LOC105377577 - +105377578 LOC105377578 - +105377579 LOC105377579 - +105377580 LOC105377580 - +105377581 LOC105377581 - +105377582 LOC105377582 - +105377584 LOC105377584 - +105377585 LINC02427 HGNC:HGNC:53358 +105377586 LINC02365 HGNC:HGNC:53285|Ensembl:ENSG00000254233 +105377587 LOC105377587 - +105377588 LOC105377588 - +105377590 LOC105377590 Ensembl:ENSG00000249679 +105377591 LOC105377591 - +105377595 RPSAP70 HGNC:HGNC:51923 +105377596 LOC105377596 - +105377599 LOC105377599 - +105377600 LINC02374 HGNC:HGNC:53296 +105377602 LINC02514 HGNC:HGNC:53503 +105377603 LOC105377603 - +105377604 LOC105377604 - +105377605 LOC105377605 - +105377606 LINC02434 HGNC:HGNC:53365 +105377607 LOC105377607 - +105377608 LOC105377608 - +105377609 LOC105377609 - +105377610 LINC02508 HGNC:HGNC:53497 +105377611 LOC105377611 - +105377612 LOC105377612 - +105377613 LOC105377613 - +105377614 LOC105377614 - +105377615 LOC105377615 - +105377616 LOC105377616 - +105377617 LINC01596 HGNC:HGNC:51591|Ensembl:ENSG00000250666 +105377619 LOC105377619 - +105377621 LOC105377621 - +105377622 LOC105377622 - +105377623 LOC105377623 Ensembl:ENSG00000250326 +105377626 LOC105377626 - +105377627 LOC105377627 - +105377628 LOC105377628 - +105377632 LOC105377632 - +105377633 LOC105377633 - +105377635 LOC105377635 - +105377636 LOC105377636 - +105377641 LOC105377641 - +105377642 LOC105377642 - +105377644 LOC105377644 - +105377645 LOC105377645 - +105377647 LOC105377647 - +105377648 LOC105377648 - +105377650 LOC105377650 - +105377651 LOC105377651 - +105377652 LINC02480 HGNC:HGNC:53454|Ensembl:ENSG00000251040 +105377654 LOC105377654 - +105377656 LINC02283 HGNC:HGNC:53200 +105377657 LOC105377657 - +105377658 LOC105377658 - +105377659 LOC105377659 - +105377660 LOC105377660 - +105377661 LOC105377661 - +105377663 LOC105377663 - +105377664 LOC105377664 - +105377665 LOC105377665 - +105377666 LOC105377666 - +105377667 LOC105377667 - +105377668 LOC105377668 - +105377670 LOC105377670 - +105377671 LINC02494 HGNC:HGNC:53479|Ensembl:ENSG00000250340 +105377672 LOC105377672 - +105377673 LOC105377673 - +105377675 LOC105377675 - +105377676 LOC105377676 - +105377677 LOC105377677 - +105377678 LOC105377678 - +105377680 LOC105377680 - +105377682 LINC01932 HGNC:HGNC:52755|Ensembl:ENSG00000253315 +105377683 LOC105377683 - +105377684 LOC105377684 - +105377685 LOC105377685 - +105377687 LOC105377687 - +105377688 LOC105377688 - +105377689 LOC105377689 - +105377690 LOC105377690 - +105377691 LOC105377691 - +105377693 LOC105377693 - +105377694 LOC105377694 - +105377696 LOC105377696 - +105377697 LOC105377697 - +105377698 LOC105377698 - +105377699 LOC105377699 - +105377700 LOC105377700 - +105377701 LINC01938 HGNC:HGNC:52761 +105377702 LOC105377702 - +105377703 LOC105377703 - +105377705 LOC105377705 - +105377706 LOC105377706 - +105377708 LOC105377708 - +105377709 LOC105377709 - +105377711 LOC105377711 - +105377712 LOC105377712 - +105377713 LOC105377713 - +105377714 LOC105377714 - +105377715 LOC105377715 - +105377716 LOC105377716 Ensembl:ENSG00000253591 +105377720 LOC105377720 - +105377721 LOC105377721 - +105377722 LOC105377722 - +105377723 LOC105377723 - +105377724 LOC105377724 - +105377725 LOC105377725 - +105377727 LOC105377727 - +105377728 LINC01944 HGNC:HGNC:52768 +105377729 LOC105377729 - +105377730 LOC105377730 - +105377731 LOC105377731 - +105377732 LOC105377732 - +105377733 LOC105377733 - +105377735 LOC105377735 - +105377736 LINC01942 HGNC:HGNC:52766|Ensembl:ENSG00000253428 +105377737 LOC105377737 - +105377739 LOC105377739 - +105377740 LOC105377740 - +105377741 LOC105377741 - +105377742 LOC105377742 - +105377743 LOC105377743 - +105377744 LOC105377744 - +105377745 LOC105377745 - +105377746 LOC105377746 - +105377747 LOC105377747 - +105377750 LOC105377750 - +105377752 LOC105377752 - +105377753 LOC105377753 - +105377754 LOC105377754 - +105377756 LOC105377756 - +105377757 LOC105377757 - +105377759 LOC105377759 - +105377761 LOC105377761 - +105377762 LOC105377762 - +105377763 LOC105377763 - +105377765 LINC02222 HGNC:HGNC:53091 +105377766 LOC105377766 - +105377769 LOC105377769 - +105377771 LOC105377771 - +105377773 LOC105377773 - +105377774 LOC105377774 - +105377775 LOC105377775 - +105377776 LOC105377776 - +105377777 LOC105377777 - +105377778 LOC105377778 - +105377779 LOC105377779 - +105377781 LOC105377781 - +105377782 LOC105377782 - +105377783 LOC105377783 - +105377784 LOC105377784 - +105377785 LOC105377785 - +105377786 LOC105377786 - +105377787 LOC105377787 - +105377789 LOC105377789 - +105377790 LOC105377790 - +105377791 LOC105377791 - +105377792 LOC105377792 - +105377793 LOC105377793 - +105377794 LOC105377794 - +105377795 LOC105377795 - +105377796 LOC105377796 - +105377797 LOC105377797 - +105377799 LOC105377799 - +105377800 LOC105377800 - +105377801 LOC105377801 - +105377803 LOC105377803 - +105377805 LOC105377805 - +105377806 LOC105377806 - +105377809 LOC105377809 - +105377811 LOC105377811 - +105377814 LOC105377814 - +105377815 LOC105377815 - +105377816 LOC105377816 - +105377817 LOC105377817 - +105377818 LOC105377818 - +105377820 RARRES2P6 HGNC:HGNC:48705 +105377822 LOC105377822 - +105377824 LOC105377824 - +105377826 LOC105377826 - +105377828 LOC105377828 - +105377830 LOC105377830 - +105377833 LOC105377833 - +105377836 LOC105377836 - +105377837 LOC105377837 - +105377838 LOC105377838 - +105377839 LOC105377839 - +105377840 LOC105377840 - +105377841 LOC105377841 - +105377842 LOC105377842 - +105377843 LOC105377843 - +105377844 LOC105377844 - +105377845 LOC105377845 - +105377846 LOC105377846 - +105377847 LOC105377847 - +105377848 LOC105377848 - +105377849 LOC105377849 - +105377850 LOC105377850 - +105377853 LOC105377853 - +105377855 LOC105377855 - +105377857 LOC105377857 - +105377858 LOC105377858 - +105377860 LINC02540 HGNC:HGNC:53573 +105377861 LOC105377861 - +105377862 LOC105377862 - +105377864 LOC105377864 - +105377865 LOC105377865 - +105377867 LOC105377867 - +105377869 LOC105377869 - +105377871 LOC105377871 - +105377872 LOC105377872 - +105377873 LOC105377873 - +105377874 LOC105377874 - +105377875 LOC105377875 - +105377876 LOC105377876 - +105377877 LOC105377877 - +105377879 LOC105377879 - +105377880 LINC01611 HGNC:HGNC:51791|Ensembl:ENSG00000231776 +105377881 LOC105377881 - +105377882 LOC105377882 - +105377884 LOC105377884 - +105377885 LOC105377885 - +105377887 LOC105377887 - +105377889 LOC105377889 - +105377890 LOC105377890 - +105377891 LOC105377891 - +105377893 LOC105377893 - +105377894 LOC105377894 - +105377896 LOC105377896 - +105377897 LOC105377897 - +105377899 LOC105377899 - +105377901 LOC105377901 - +105377904 LOC105377904 - +105377905 LOC105377905 - +105377907 LOC105377907 - +105377908 LOC105377908 - +105377909 LOC105377909 - +105377910 LOC105377910 - +105377911 LOC105377911 - +105377913 LOC105377913 - +105377916 LOC105377916 - +105377917 LOC105377917 - +105377918 LOC105377918 - +105377920 LOC105377920 - +105377921 LOC105377921 - +105377922 LOC105377922 - +105377923 LOC105377923 - +105377924 LOC105377924 Ensembl:ENSG00000282408 +105377926 LINC02526 HGNC:HGNC:53550 +105377927 LOC105377927 - +105377928 LOC105377928 - +105377929 LOC105377929 - +105377932 LOC105377932 - +105377933 LOC105377933 - +105377934 LOC105377934 - +105377935 LOC105377935 - +105377936 LOC105377936 - +105377937 LOC105377937 - +105377938 LOC105377938 - +105377939 LOC105377939 - +105377940 LOC105377940 - +105377941 LOC105377941 - +105377944 LOC105377944 - +105377945 LOC105377945 - +105377946 LINC02527 HGNC:HGNC:53553 +105377947 LOC105377947 - +105377949 LOC105377949 - +105377950 LOC105377950 - +105377951 LOC105377951 - +105377952 LOC105377952 - +105377953 LOC105377953 - +105377955 LOC105377955 - +105377956 LOC105377956 - +105377957 LINC02518 HGNC:HGNC:53509 +105377958 LOC105377958 - +105377959 LOC105377959 - +105377960 LOC105377960 - +105377961 LOC105377961 - +105377962 LINC02534 HGNC:HGNC:53567 +105377963 LOC105377963 - +105377964 LOC105377964 - +105377967 LOC105377967 - +105377971 LOC105377971 - +105377972 LOC105377972 - +105377973 LOC105377973 - +105377975 LOC105377975 - +105377977 LOC105377977 - +105377978 LOC105377978 - +105377979 LOC105377979 - +105377981 LOC105377981 - +105377982 LOC105377982 - +105377984 LOC105377984 - +105377986 LOC105377986 - +105377989 LOC105377989 - +105377991 LOC105377991 - +105377992 LOC105377992 - +105377993 LOC105377993 - +105377994 LOC105377994 - +105377995 LOC105377995 - +105377996 LOC105377996 - +105377997 LINC02536 HGNC:HGNC:53570 +105377998 LOC105377998 - +105377999 LOC105377999 - +105378000 LOC105378000 - +105378002 LOC105378002 - +105378003 LOC105378003 - +105378004 LOC105378004 - +105378005 LOC105378005 - +105378008 LOC105378008 - +105378009 LOC105378009 - +105378010 LOC105378010 - +105378011 LOC105378011 - +105378012 LOC105378012 - +105378013 LOC105378013 - +105378017 LOC105378017 - +105378018 LOC105378018 - +105378020 LINC02528 HGNC:HGNC:53554 +105378021 LOC105378021 - +105378023 LOC105378023 - +105378024 LOC105378024 - +105378025 LOC105378025 - +105378026 LOC105378026 - +105378027 LOC105378027 - +105378029 LOC105378029 - +105378030 LOC105378030 - +105378031 LOC105378031 - +105378032 LOC105378032 - +105378035 LOC105378035 - +105378036 LOC105378036 - +105378039 LOC105378039 - +105378040 LOC105378040 - +105378041 LOC105378041 - +105378042 LOC105378042 - +105378043 LOC105378043 - +105378044 LOC105378044 Ensembl:ENSG00000226249 +105378046 LOC105378046 - +105378047 LOC105378047 - +105378049 TAB2-AS1 HGNC:HGNC:53508|Ensembl:ENSG00000225924 +105378050 LOC105378050 - +105378051 LOC105378051 - +105378052 LOC105378052 Ensembl:ENSG00000216621 +105378054 LOC105378054 - +105378061 LOC105378061 - +105378062 LOC105378062 - +105378065 LOC105378065 - +105378066 LOC105378066 - +105378067 LOC105378067 - +105378068 LOC105378068 - +105378069 LOC105378069 - +105378071 LOC105378071 - +105378072 LOC105378072 - +105378073 LOC105378073 - +105378075 LOC105378075 - +105378076 LOC105378076 - +105378077 LOC105378077 - +105378078 LOC105378078 - +105378083 LOC105378083 - +105378084 LOC105378084 - +105378085 LOC105378085 - +105378087 LOC105378087 - +105378088 LOC105378088 - +105378091 LOC105378091 - +105378093 LOC105378093 - +105378094 LOC105378094 - +105378095 LOC105378095 - +105378097 LOC105378097 - +105378098 LOC105378098 - +105378099 LOC105378099 - +105378100 LOC105378100 - +105378102 LOC105378102 - +105378104 LOC105378104 - +105378105 LOC105378105 - +105378106 LOC105378106 - +105378108 LOC105378108 - +105378109 LOC105378109 - +105378110 LOC105378110 - +105378111 MEAT6 - +105378113 LOC105378113 - +105378114 LOC105378114 - +105378115 LOC105378115 - +105378116 LOC105378116 - +105378117 LOC105378117 - +105378118 LOC105378118 - +105378119 LOC105378119 - +105378120 LOC105378120 - +105378122 LOC105378122 - +105378123 LOC105378123 - +105378124 LOC105378124 - +105378126 LOC105378126 - +105378127 LOC105378127 - +105378128 LOC105378128 - +105378129 LOC105378129 - +105378130 LOC105378130 - +105378131 LOC105378131 - +105378132 LOC105378132 - +105378135 LOC105378135 - +105378137 LOC105378137 Ensembl:ENSG00000237987 +105378138 LOC105378138 - +105378139 LOC105378139 - +105378140 LOC105378140 - +105378141 LOC105378141 - +105378142 LOC105378142 - +105378143 LOC105378143 - +105378144 LOC105378144 - +105378145 LOC105378145 - +105378146 LOC105378146 - +105378147 LINC02519 HGNC:HGNC:53510 +105378148 LOC105378148 - +105378149 LOC105378149 - +105378150 LOC105378150 - +105378153 LOC105378153 - +105378155 LOC105378155 - +105378157 LOC105378157 - +105378159 LOC105378159 - +105378161 LOC105378161 - +105378166 LOC105378166 - +105378168 LOC105378168 - +105378170 LOC105378170 - +105378171 LOC105378171 - +105378174 LOC105378174 - +105378175 LOC105378175 - +105378177 LOC105378177 - +105378178 LOC105378178 - +105378179 LOC105378179 - +105378180 LOC105378180 - +105378182 LOC105378182 - +105378183 LOC105378183 - +105378184 LOC105378184 - +105378185 LOC105378185 - +105378187 LOC105378187 - +105378189 LOC105378189 - +105378193 LOC105378193 - +105378194 LOC105378194 - +105378198 LOC105378198 - +105378199 LOC105378199 - +105378204 LOC105378204 - +105378208 LOC105378208 - +105378209 LOC105378209 - +105378210 LOC105378210 - +105378211 LOC105378211 - +105378213 LOC105378213 - +105378214 LOC105378214 - +105378215 CTB-99A3.1 - +105378217 STK32A-AS1 HGNC:HGNC:53468 +105378218 LOC105378218 - +105378220 LOC105378220 Ensembl:ENSG00000248109|Vega:OTTHUMG00000163424 +105378221 LOC105378221 - +105378224 LOC105378224 - +105378225 LOC105378225 - +105378226 LOC105378226 - +105378228 LOC105378228 - +105378230 LOC105378230 - +105378231 LOC105378231 Ensembl:ENSG00000260581 +105378234 LOC105378234 - +105378235 LOC105378235 - +105378236 LOC105378236 - +105378237 LOC105378237 - +105378238 LINC01861 HGNC:HGNC:52680 +105378239 LOC105378239 - +105378240 LOC105378240 - +105378242 LOC105378242 - +105378243 LOC105378243 - +105378247 LOC105378247 - +105378248 LOC105378248 - +105378250 LOC105378250 - +105378255 LOC105378255 - +105378256 LOC105378256 - +105378258 LOC105378258 - +105378260 LOC105378260 - +105378261 LOC105378261 - +105378262 LOC105378262 - +105378267 LOC105378267 - +105378268 LOC105378268 - +105378269 LOC105378269 - +105378270 LOC105378270 - +105378271 LOC105378271 - +105378272 LOC105378272 - +105378274 LOC105378274 - +105378275 LOC105378275 - +105378277 LOC105378277 Ensembl:ENSG00000236769 +105378281 LOC105378281 - +105378283 LOC105378283 - +105378286 LOC105378286 - +105378287 LOC105378287 - +105378289 LOC105378289 - +105378291 LOC105378291 - +105378292 LOC105378292 - +105378298 LOC105378298 - +105378299 LOC105378299 - +105378302 LOC105378302 - +105378305 LOC105378305 - +105378306 LOC105378306 - +105378307 LOC105378307 - +105378308 LOC105378308 - +105378309 LOC105378309 - +105378310 LOC105378310 - +105378311 LOC105378311 Ensembl:ENSG00000234173 +105378313 LOC105378313 - +105378314 LOC105378314 - +105378316 LOC105378316 - +105378318 LOC105378318 - +105378319 LOC105378319 - +105378320 LOC105378320 - +105378323 LOC105378323 - +105378325 LOC105378325 Ensembl:ENSG00000234756 +105378326 LOC105378326 - +105378327 LOC105378327 - +105378328 LOC105378328 Ensembl:ENSG00000224301 +105378329 LOC105378329 - +105378330 LOC105378330 - +105378332 LOC105378332 - +105378333 LOC105378333 - +105378334 LOC105378334 - +105378335 LOC105378335 - +105378336 LOC105378336 - +105378337 LOC105378337 - +105378338 LOC105378338 - +105378339 LOC105378339 - +105378340 LOC105378340 - +105378342 LOC105378342 - +105378345 LOC105378345 - +105378346 LOC105378346 - +105378347 LOC105378347 - +105378349 LOC105378349 Ensembl:ENSG00000259267 +105378350 LOC105378350 - +105378351 LOC105378351 - +105378353 LOC105378353 - +105378355 LOC105378355 - +105378356 LOC105378356 - +105378358 LOC105378358 - +105378360 LOC105378360 - +105378367 LOC105378367 - +105378369 LOC105378369 - +105378372 LOC105378372 - +105378373 LOC105378373 - +105378374 LOC105378374 - +105378375 LOC105378375 - +105378378 LOC105378378 - +105378379 LOC105378379 - +105378383 LOC105378383 - +105378385 LOC105378385 Ensembl:ENSG00000226676 +105378386 LOC105378386 - +105378387 LOC105378387 - +105378389 LOC105378389 - +105378390 LOC105378390 - +105378392 LOC105378392 - +105378393 LOC105378393 - +105378394 LOC105378394 - +105378396 LOC105378396 - +105378397 LOC105378397 - +105378398 LOC105378398 - +105378399 LOC105378399 - +105378400 LOC105378400 - +105378401 LOC105378401 - +105378402 LOC105378402 - +105378403 LOC105378403 - +105378404 LOC105378404 - +105378406 LOC105378406 - +105378407 LOC105378407 - +105378408 LOC105378408 - +105378409 LOC105378409 - +105378410 LOC105378410 - +105378412 LOC105378412 - +105378414 LOC105378414 - +105378415 LOC105378415 - 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LOC105378472 - +105378473 LOC105378473 - +105378474 LOC105378474 - +105378475 LOC105378475 - +105378476 LOC105378476 - +105378477 LOC105378477 - +105378478 LOC105378478 - +105378479 LOC105378479 - +105378480 LOC105378480 - +105378481 LOC105378481 - +105378482 LOC105378482 - +105378483 LOC105378483 - +105378484 LOC105378484 - +105378485 LOC105378485 - +105378486 LOC105378486 - +105378487 LOC105378487 - +105378488 LOC105378488 - +105378489 LOC105378489 - +105378490 LOC105378490 - +105378492 LOC105378492 - +105378493 LOC105378493 - +105378494 LOC105378494 - +105378496 LOC105378496 - +105378497 LOC105378497 - +105378498 LOC105378498 - +105378499 LOC105378499 Ensembl:ENSG00000232767 +105378500 LOC105378500 - +105378502 LOC105378502 - +105378504 LOC105378504 - +105378506 LOC105378506 - +105378507 LOC105378507 - +105378511 LOC105378511 - +105378512 LOC105378512 - +105378513 LOC105378513 - +105378515 LOC105378515 - +105378516 LOC105378516 - +105378518 LOC105378518 - +105378519 LOC105378519 - +105378520 LOC105378520 - +105378521 LOC105378521 - +105378522 LOC105378522 - +105378523 LOC105378523 - +105378524 LOC105378524 - +105378525 LOC105378525 - +105378526 LOC105378526 - +105378530 LOC105378530 - +105378531 LOC105378531 - +105378532 LOC105378532 - +105378533 LOC105378533 Ensembl:ENSG00000231138 +105378534 LOC105378534 - +105378536 LOC105378536 - +105378539 LOC105378539 - +105378541 LOC105378541 - +105378542 LOC105378542 - +105378543 LOC105378543 - +105378544 LOC105378544 - +105378545 LOC105378545 - +105378547 LOC105378547 - +105378548 LOC105378548 - +105378549 LOC105378549 - +105378550 LOC105378550 - +105378551 LOC105378551 - +105378552 LOC105378552 - +105378553 AS-PTPRE - +105378554 LOC105378554 - +105378555 LOC105378555 - +105378556 LOC105378556 - +105378557 LOC105378557 - +105378558 LOC105378558 - +105378560 LOC105378560 - +105378561 LOC105378561 - +105378562 LOC105378562 - +105378563 LOC105378563 - +105378565 LOC105378565 - +105378566 LOC105378566 - +105378567 LOC105378567 - +105378568 LOC105378568 - +105378569 LOC105378569 - +105378570 LOC105378570 - +105378571 LOC105378571 - +105378572 LOC105378572 - +105378573 LOC105378573 - +105378574 LOC105378574 - +105378575 LOC105378575 - +105378576 LOC105378576 - +105378577 LOC105378577 - +105378580 LOC105378580 - +105378585 LOC105378585 - +105378586 LOC105378586 - +105378589 LOC105378589 - +105378590 LOC105378590 - +105378591 LOC105378591 Ensembl:ENSG00000226969 +105378592 LOC105378592 - +105378593 LOC105378593 - +105378597 LOC105378597 - +105378598 LOC105378598 - +105378599 LOC105378599 - +105378600 LOC105378600 - +105378601 LOC105378601 - +105378602 LOC105378602 - +105378603 LOC105378603 - +105378604 LOC105378604 - +105378605 LOC105378605 - +105378606 LOC105378606 - +105378607 LOC105378607 - +105378608 LOC105378608 - +105378609 LOC105378609 - +105378610 LOC105378610 - +105378612 LOC105378612 - +105378614 LOC105378614 Ensembl:ENSG00000235185 +105378615 LOC105378615 - +105378616 LINC01715 HGNC:HGNC:52502 +105378617 LOC105378617 - +105378618 LOC105378618 - +105378619 LOC105378619 - +105378620 LOC105378620 - +105378621 LOC105378621 - +105378622 LINC01778 HGNC:HGNC:52568 +105378623 LOC105378623 - +105378625 LOC105378625 - +105378626 LOC105378626 - +105378627 LOC105378627 - +105378628 LOC105378628 - +105378629 LOC105378629 - +105378631 LOC105378631 - +105378632 LOC105378632 - +105378635 LOC105378635 - +105378638 LOC105378638 - +105378639 LOC105378639 - +105378640 LOC105378640 - +105378641 LOC105378641 - +105378642 LOC105378642 - +105378644 LOC105378644 - +105378645 LOC105378645 - +105378646 LOC105378646 - +105378647 LOC105378647 - +105378648 LOC105378648 - +105378649 LOC105378649 - +105378650 LOC105378650 - +105378651 LOC105378651 - +105378653 LOC105378653 - +105378654 LOC105378654 - +105378655 LOC105378655 - +105378656 LINC01685 HGNC:HGNC:52473 +105378657 LOC105378657 - +105378658 LOC105378658 - +105378660 LOC105378660 - +105378662 LOC105378662 - +105378663 LOC105378663 Ensembl:ENSG00000228436 +105378665 LOC105378665 - +105378666 LOC105378666 - +105378667 LOC105378667 - +105378668 LOC105378668 Ensembl:ENSG00000236546 +105378669 LOC105378669 - +105378671 LOC105378671 - +105378672 LOC105378672 - +105378673 LOC105378673 - +105378674 LOC105378674 - +105378675 LOC105378675 - +105378676 LOC105378676 - +105378678 LOC105378678 - +105378683 LOC105378683 - +105378685 LOC105378685 - +105378687 LOC105378687 Ensembl:ENSG00000234694 +105378688 LOC105378688 - +105378689 LOC105378689 - +105378690 LOC105378690 - +105378691 LOC105378691 - +105378693 LOC105378693 - +105378694 LOC105378694 - +105378695 LOC105378695 - +105378696 LOC105378696 - +105378697 LOC105378697 - +105378698 LOC105378698 - +105378699 LOC105378699 - +105378701 LOC105378701 - +105378706 LOC105378706 - +105378708 LOC105378708 - +105378709 LOC105378709 - +105378710 LOC105378710 - +105378711 LOC105378711 - +105378712 LOC105378712 - +105378714 LOC105378714 - +105378715 LOC105378715 - +105378716 LINC01562 HGNC:HGNC:51335 +105378717 LOC105378717 - +105378719 LOC105378719 - +105378720 LOC105378720 - +105378721 LOC105378721 Ensembl:ENSG00000266993 +105378723 LOC105378723 - +105378724 LOC105378724 - +105378726 LOC105378726 - +105378728 LOC105378728 - +105378730 LOC105378730 - +105378731 LOC105378731 - +105378732 LINC01771 HGNC:HGNC:52561|Ensembl:ENSG00000225675 +105378733 LOC105378733 - +105378734 LOC105378734 - +105378735 LOC105378735 - +105378736 LOC105378736 - +105378737 LOC105378737 - +105378738 LINC01755 HGNC:HGNC:52543|Ensembl:ENSG00000233079 +105378739 LINC01753 HGNC:HGNC:52541|Ensembl:ENSG00000230250 +105378740 LOC105378740 - +105378741 LOC105378741 - +105378744 LINC01767 HGNC:HGNC:52557 +105378745 LOC105378745 - +105378746 LOC105378746 - +105378747 LOC105378747 - +105378748 LOC105378748 - +105378751 LOC105378751 - +105378753 LOC105378753 Ensembl:ENSG00000232453 +105378756 LOC105378756 - +105378758 LOC105378758 - +105378760 LOC105378760 - +105378761 LOC105378761 - +105378763 LINC01748 HGNC:HGNC:52535 +105378764 LOC105378764 - +105378766 LOC105378766 - +105378768 LOC105378768 - +105378769 LINC01739 HGNC:HGNC:52527 +105378770 LOC105378770 - +105378771 LOC105378771 - +105378772 LOC105378772 - +105378773 LOC105378773 - +105378774 LOC105378774 - +105378776 LOC105378776 - +105378779 LOC105378779 - +105378780 LOC105378780 - +105378781 LOC105378781 - +105378782 LOC105378782 - +105378783 LOC105378783 - +105378785 LINC01707 HGNC:HGNC:52495|Ensembl:ENSG00000223883 +105378786 LOC105378786 - +105378787 LOC105378787 - +105378788 LINC01758 HGNC:HGNC:52547 +105378789 LOC105378789 - +105378790 LOC105378790 - +105378792 LOC105378792 - +105378793 LOC105378793 - +105378794 LOC105378794 - +105378795 LOC105378795 - +105378796 LOC105378796 - +105378797 LOC105378797 - +105378798 LOC105378798 - +105378799 LOC105378799 - +105378800 LOC105378800 - +105378801 LOC105378801 - +105378802 LOC105378802 - +105378803 LRRC53 HGNC:HGNC:25255|Ensembl:ENSG00000162621|Vega:OTTHUMG00000009621 +105378805 LOC105378805 - +105378806 LOC105378806 - +105378807 LOC105378807 - +105378808 LOC105378808 - +105378810 LOC105378810 - +105378811 LOC105378811 - +105378812 LOC105378812 - +105378813 LOC105378813 - +105378814 LOC105378814 - +105378816 LOC105378816 - +105378819 LOC105378819 - +105378821 LOC105378821 - +105378823 LOC105378823 - +105378824 LOC105378824 - +105378825 LOC105378825 - +105378826 LOC105378826 - +105378827 LOC105378827 - +105378828 LOC105378828 Ensembl:ENSG00000261737 +105378831 LOC105378831 - +105378833 LOC105378833 - +105378834 LOC105378834 - +105378835 LOC105378835 - +105378836 LOC105378836 - +105378838 LOC105378838 - +105378839 LOC105378839 - +105378841 LOC105378841 - +105378842 LOC105378842 - +105378843 LOC105378843 - +105378844 LOC105378844 - +105378845 LOC105378845 - +105378847 LOC105378847 - +105378848 LOC105378848 - +105378849 LOC105378849 - +105378850 LOC105378850 - +105378851 LOC105378851 - +105378852 LOC105378852 - +105378853 LOC105378853 Ensembl:ENSG00000233593 +105378854 LINC01763 HGNC:HGNC:52554 +105378855 LOC105378855 - +105378856 LOC105378856 - +105378858 LOC105378858 - +105378859 LOC105378859 - +105378860 LOC105378860 - +105378861 LOC105378861 - +105378862 LOC105378862 - +105378863 LOC105378863 - +105378864 LOC105378864 - +105378866 LOC105378866 - +105378867 LOC105378867 - +105378872 LINC01709 HGNC:HGNC:52497 +105378874 LOC105378874 - +105378877 LOC105378877 - +105378878 LOC105378878 - +105378879 LOC105378879 - +105378880 LOC105378880 - +105378881 LOC105378881 - +105378882 LOC105378882 - +105378883 LOC105378883 - +105378884 LINC01677 HGNC:HGNC:52465 +105378885 LOC105378885 - +105378886 LOC105378886 - +105378887 LOC105378887 - +105378888 LOC105378888 - +105378889 LINC01661 HGNC:HGNC:52449 +105378890 LOC105378890 - +105378891 LOC105378891 - +105378892 LOC105378892 - +105378893 LOC105378893 - +105378895 LOC105378895 - +105378897 LOC105378897 - +105378898 LOC105378898 - +105378899 LOC105378899 - +105378901 LOC105378901 - +105378903 LOC105378903 - +105378904 LOC105378904 - +105378906 LOC105378906 - +105378909 LOC105378909 - +105378910 LOC105378910 - +105378911 LOC105378911 - +105378912 HP08777 - +105378913 LOC105378913 - +105378914 LOC105378914 - +105378915 LOC105378915 - +105378916 LINC01765 HGNC:HGNC:52555 +105378917 LOC105378917 - +105378918 LOC105378918 - +105378919 LOC105378919 - +105378920 LOC105378920 - +105378924 LOC105378924 - +105378925 LOC105378925 - +105378926 LOC105378926 - +105378927 LOC105378927 - +105378929 LOC105378929 - +105378930 LOC105378930 - +105378933 LOC105378933 Ensembl:ENSG00000226172 +105378934 LINC01780 HGNC:HGNC:52570|Ensembl:ENSG00000232650 +105378935 LOC105378935 - +105378936 LOC105378936 - +105378937 LOC105378937 - +105378938 LOC105378938 - +105378939 LOC105378939 - +105378940 LOC105378940 - +105378941 LOC105378941 - +105378943 LOC105378943 - +105378944 LOC105378944 - +105378945 LOC105378945 - +105378946 LOC105378946 - +105378947 LOC105378947 - +105378948 LOC105378948 - +105378949 LOC105378949 - +105378950 LOC105378950 - +105378951 LOC105378951 - +105378952 KLF18 HGNC:HGNC:51793 +105378954 LOC105378954 - +105378955 LOC105378955 - +105378956 LOC105378956 - +105378959 LOC105378959 - +105378960 LINC02118 HGNC:HGNC:52974|Ensembl:ENSG00000248789 +105378961 LOC105378961 - +105378962 LOC105378962 - +105378963 LOC105378963 - +105378964 LOC105378964 - +105378965 LOC105378965 - +105378966 LINC02105 HGNC:HGNC:52960|Ensembl:ENSG00000250447 +105378967 LOC105378967 - +105378968 LOC105378968 - +105378969 LOC105378969 - +105378971 LOC105378971 - +105378973 LOC105378973 - +105378975 LOC105378975 - +105378976 LOC105378976 - +105378977 LOC105378977 - +105378978 LOC105378978 - +105378979 LOC105378979 - +105378980 LOC105378980 - +105378983 LOC105378983 - +105378984 LOC105378984 - +105378986 LOC105378986 - +105378988 LOC105378988 - +105378991 LOC105378991 Ensembl:ENSG00000233847 +105378992 LINC02057 HGNC:HGNC:52900 +105378993 LOC105378993 - +105378994 LOC105378994 - +105378995 LOC105378995 - +105378996 LOC105378996 - +105378997 LOC105378997 - +105378998 LOC105378998 - +105378999 LOC105378999 - +105379002 LOC105379002 - +105379003 LOC105379003 - +105379004 LOC105379004 - +105379005 LOC105379005 - +105379006 LINC02242 HGNC:HGNC:53127 +105379007 LOC105379007 - +105379010 LOC105379010 - +105379011 LOC105379011 - +105379012 LOC105379012 - +105379013 LOC105379013 - +105379014 LOC105379014 - +105379015 LOC105379015 - +105379016 LOC105379016 - +105379020 LOC105379020 - +105379021 LOC105379021 - +105379023 LOC105379023 - +105379025 LOC105379025 - +105379026 LOC105379026 - +105379027 LOC105379027 - +105379028 LOC105379028 - +105379030 LOC105379030 Ensembl:ENSG00000251599 +105379031 LOC105379031 - +105379033 LINC02230 HGNC:HGNC:53099 +105379034 LOC105379034 - +105379035 LOC105379035 - +105379036 LINC02122 HGNC:HGNC:52979 +105379037 LINC01157 HGNC:HGNC:49512 +105379039 LOC105379039 - +105379040 LOC105379040 - +105379041 LOC105379041 - +105379042 LOC105379042 - +105379043 LOC105379043 - +105379045 LOC105379045 - +105379047 LOC105379047 - +105379048 LOC105379048 - +105379049 LOC105379049 - +105379050 LOC105379050 - +105379051 LOC105379051 - +105379052 LOC105379052 - +105379053 LOC105379053 - +105379054 VCAN-AS1 HGNC:HGNC:40163|Ensembl:ENSG00000249835 +105379055 LOC105379055 - +105379057 LOC105379057 - +105379059 LOC105379059 - +105379061 LOC105379061 - +105379062 LOC105379062 - +105379063 LOC105379063 - +105379064 LOC105379064 - +105379065 LOC105379065 - +105379066 LOC105379066 - +105379069 LINC02144 HGNC:HGNC:53004 +105379070 LOC105379070 - +105379073 LOC105379073 - +105379074 LOC105379074 - +105379076 LINC02161 HGNC:HGNC:53022 +105379077 LOC105379077 - +105379078 LOC105379078 - +105379080 LOC105379080 - +105379082 LOC105379082 - +105379083 LOC105379083 - +105379085 LOC105379085 - +105379086 LOC105379086 - +105379087 LOC105379087 - +105379089 LOC105379089 - +105379090 LOC105379090 - +105379091 LOC105379091 - +105379092 LOC105379092 - +105379094 LOC105379094 - +105379096 LOC105379096 - +105379098 LINC01846 HGNC:HGNC:52661 +105379099 LOC105379099 - +105379100 LOC105379100 - +105379101 LOC105379101 - +105379102 LOC105379102 - +105379103 LOC105379103 - +105379104 LOC105379104 - +105379105 LOC105379105 - +105379107 LOC105379107 - +105379109 LOC105379109 Ensembl:ENSG00000251574 +105379110 LOC105379110 - +105379111 LOC105379111 - +105379114 LOC105379114 - +105379117 LOC105379117 - +105379118 LOC105379118 - +105379119 LOC105379119 - +105379121 LOC105379121 - +105379122 LOC105379122 - +105379123 LOC105379123 - +105379126 LOC105379126 - +105379127 LOC105379127 - +105379129 LOC105379129 - +105379130 LOC105379130 - +105379132 SEMA6A-AS2 HGNC:HGNC:52754 +105379133 LOC105379133 - +105379134 LOC105379134 - +105379135 LOC105379135 - +105379136 LOC105379136 - +105379137 LOC105379137 - +105379138 LOC105379138 - +105379139 LOC105379139 - +105379141 LINC02216 HGNC:HGNC:53083|Ensembl:ENSG00000249551 +105379143 LOC105379143 Ensembl:ENSG00000249494 +105379144 LOC105379144 - +105379145 LOC105379145 - +105379147 LOC105379147 - +105379148 LOC105379148 - +105379149 LOC105379149 - +105379150 LOC105379150 - +105379151 LOC105379151 - +105379152 LOC105379152 - +105379154 LOC105379154 - +105379155 LOC105379155 - +105379156 LOC105379156 - +105379157 LOC105379157 - +105379158 LOC105379158 - +105379160 LOC105379160 - +105379162 LOC105379162 - +105379163 LOC105379163 - +105379164 LOC105379164 Ensembl:ENSG00000248799 +105379167 LOC105379167 - +105379168 LOC105379168 - +105379169 LOC105379169 - +105379170 LOC105379170 - +105379171 LOC105379171 - +105379172 LOC105379172 - +105379173 LOC105379173 - +105379174 LOC105379174 - +105379175 LOC105379175 - +105379176 LOC105379176 - +105379177 LOC105379177 - +105379178 LOC105379178 - +105379179 LOC105379179 - +105379180 CTB-3M24.3 - +105379181 CTB-49A3.2 - +105379182 LOC105379182 - +105379183 LOC105379183 - +105379185 LOC105379185 - +105379188 LOC105379188 - +105379189 LOC105379189 - +105379191 CTB-1I21.1 - +105379192 LOC105379192 - +105379193 LOC105379193 - +105379194 LOC105379194 Ensembl:ENSG00000253404 +105379195 LOC105379195 - +105379196 LOC105379196 - +105379197 PDZPH1P HGNC:HGNC:51488 +105379198 LOC105379198 - +105379199 LOC105379199 - +105379202 FAM30B HGNC:HGNC:31023 +105379203 LOC105379203 - +105379205 LOC105379205 - +105379207 LOC105379207 - +105379208 LOC105379208 - +105379212 LOC105379212 - +105379215 LOC105379215 - +105379216 LOC105379216 - +105379219 FAM85B HGNC:HGNC:32160 +105379220 LOC105379220 - +105379222 LOC105379222 - +105379224 LOC105379224 - +105379225 LOC105379225 - +105379227 LOC105379227 - +105379228 LOC105379228 - +105379230 LOC105379230 - +105379231 LOC105379231 - +105379234 LOC105379234 - +105379235 LOC105379235 - +105379237 LOC105379237 - +105379241 LOC105379241 - +105379242 LOC105379242 - +105379243 LOC105379243 - +105379244 LOC105379244 - +105379245 LOC105379245 - +105379246 LOC105379246 - +105379249 LOC105379249 - +105379250 LOC105379250 - +105379251 LOC105379251 - +105379252 LOC105379252 Ensembl:ENSG00000274628 +105379255 LOC105379255 - +105379257 LOC105379257 - +105379263 LOC105379263 - +105379264 LOC105379264 - +105379265 LOC105379265 - +105379266 LOC105379266 - +105379267 LOC105379267 - +105379268 FAM197Y8 HGNC:HGNC:37470 +105379269 FAM197Y7 HGNC:HGNC:37469 +105379270 FAM197Y6 HGNC:HGNC:37468 +105379271 LOC105379271 - +105379272 LOC105379272 - +105379273 LOC105379273 - +105379274 LOC105379274 - +105379275 LOC105379275 - +105379276 LOC105379276 - +105379278 LOC105379278 - +105379279 LOC105379279 - +105379280 LOC105379280 - +105379281 LOC105379281 - +105379282 LOC105379282 - +105379283 LOC105379283 - +105379286 LOC105379286 - +105379289 LOC105379289 - +105379292 LOC105379292 - +105379297 LOC105379297 - +105379300 LOC105379300 - +105379301 LOC105379301 - +105379303 LOC105379303 - +105379306 LOC105379306 - +105379308 LOC105379308 - +105379309 LOC105379309 - +105379310 LOC105379310 - +105379311 LOC105379311 - +105379312 LOC105379312 - +105379314 LOC105379314 - +105379315 LOC105379315 - +105379316 LOC105379316 - +105379318 LOC105379318 - +105379319 LOC105379319 - +105379321 LOC105379321 - +105379322 LOC105379322 - +105379325 LOC105379325 - +105379326 LOC105379326 - +105379327 LOC105379327 - +105379328 LOC105379328 - +105379329 LOC105379329 - +105379330 LOC105379330 - +105379331 LOC105379331 - +105379332 LOC105379332 - +105379333 LOC105379333 - +105379335 LOC105379335 - +105379336 LOC105379336 - +105379337 LOC105379337 - +105379339 LOC105379339 - +105379340 LOC105379340 - +105379342 LOC105379342 - +105379343 LOC105379343 - +105379344 LOC105379344 - +105379345 LOC105379345 - +105379346 LOC105379346 - +105379349 LOC105379349 - +105379350 LOC105379350 - +105379351 LOC105379351 - +105379352 LOC105379352 - +105379354 LOC105379354 - +105379355 LOC105379355 - +105379356 LOC105379356 - +105379357 LOC105379357 - +105379358 LOC105379358 - +105379360 LOC105379360 - +105379361 LOC105379361 - +105379362 LOC105379362 - +105379363 LOC105379363 - +105379364 LOC105379364 - +105379365 LOC105379365 - +105379366 LOC105379366 - +105379368 LOC105379368 - +105379369 LOC105379369 - +105379370 LOC105379370 - +105379371 LOC105379371 - +105379374 LOC105379374 - +105379375 LOC105379375 - +105379376 LOC105379376 - +105379377 LOC105379377 - +105379378 LOC105379378 - +105379379 LOC105379379 - +105379380 LOC105379380 - +105379381 LOC105379381 - +105379382 LOC105379382 - +105379383 LOC105379383 - +105379384 LOC105379384 - +105379385 LOC105379385 - +105379386 LOC105379386 - +105379387 LOC105379387 - +105379388 LOC105379388 - +105379389 LOC105379389 - +105379390 LOC105379390 - +105379391 LOC105379391 Ensembl:ENSG00000253396 +105379392 LOC105379392 - +105379393 LOC105379393 - +105379395 LOC105379395 - +105379396 LOC105379396 - +105379397 LOC105379397 - +105379400 LOC105379400 - +105379403 LOC105379403 - +105379404 LOC105379404 - +105379406 LOC105379406 - +105379407 LOC105379407 - +105379409 LOC105379409 - +105379412 LOC105379412 - +105379413 LOC105379413 - +105379414 LOC105379414 - +105379417 LOC105379417 - +105379418 LOC105379418 - +105379420 LOC105379420 - +105379426 LOC105379426 - +105379427 ZNF73 MIM:194547|HGNC:HGNC:13143 +105379428 LOC105379428 - +105379430 LOC105379430 - +105379434 LOC105379434 - +105379435 LOC105379435 - +105379437 LOC105379437 - +105379438 LOC105379438 - +105379439 LOC105379439 - +105379442 LOC105379442 - +105379443 LOC105379443 - +105379444 LOC105379444 - +105379445 LOC105379445 - +105379446 LOC105379446 - +105379447 LOC105379447 - +105379448 LOC105379448 - +105379450 LOC105379450 - +105379451 LOC105379451 - +105379452 LOC105379452 - +105379453 LOC105379453 - +105379454 LOC105379454 - +105379457 LOC105379457 - +105379460 LOC105379460 - +105379461 LOC105379461 - +105379464 LOC105379464 - +105379466 LOC105379466 - +105379473 LOC105379473 - +105379474 LOC105379474 - +105379475 LOC105379475 - +105379476 LOC105379476 - +105379477 LOC105379477 - +105379478 LINC01598 HGNC:HGNC:51597 +105379479 DUX4L34 HGNC:HGNC:51772 +105379480 LOC105379480 - +105379481 LOC105379481 - +105379482 LOC105379482 - +105379483 LOC105379483 - +105379484 LOC105379484 - +105379487 LINC01670 HGNC:HGNC:52458|Ensembl:ENSG00000279094 +105379488 LOC105379488 - +105379489 LOC105379489 - +105379490 LOC105379490 - +105379491 LOC105379491 - +105379493 CH507-145C22.1 - +105379497 LOC105379497 - +105379499 LOC105379499 - +105379501 LOC105379501 - +105379502 LOC105379502 - +105379503 LOC105379503 - +105379504 LOC105379504 - +105379505 LOC105379505 - +105379506 LOC105379506 - +105379507 LOC105379507 - +105379508 LOC105379508 - +105379511 LOC105379511 - +105379513 LOC105379513 - +105379514 LOC105379514 - +105379516 LOC105379516 - +105379518 LOC105379518 - +105379521 LOC105379521 - +105379522 LOC105379522 - +105379523 LOC105379523 - +105379524 LOC105379524 - +105379525 LOC105379525 - +105379527 LOC105379527 - +105379528 LOC105379528 - +105379529 LOC105379529 - +105379533 LOC105379533 - +105379535 LOC105379535 - +105379537 LOC105379537 - +105379539 LOC105379539 - +105379540 LOC105379540 - +105379544 LOC105379544 - +105379545 LOC105379545 - +105379547 LOC105379547 - +105379548 LOC105379548 - +105379549 LOC105379549 - +105379550 LOC105379550 - +105379551 LOC105379551 - +105379554 LOC105379554 - +105379555 LOC105379555 - +105379556 LOC105379556 - +105379557 LOC105379557 - +105379561 LOC105379561 - +105379562 LOC105379562 - +105379563 LOC105379563 - +105379564 LOC105379564 - +105379565 LOC105379565 - +105379566 LOC105379566 - +105379573 LOC105379573 - +105379574 LOC105379574 - +105379575 LOC105379575 - +105379576 LOC105379576 - +105379578 LOC105379578 - +105379580 LOC105379580 - +105379583 LOC105379583 - +105379585 LOC105379585 - +105379586 LOC105379586 - +105379589 LOC105379589 - +105379593 LOC105379593 - +105379597 LOC105379597 - +105379599 LOC105379599 - +105379600 LOC105379600 - +105379601 LOC105379601 - +105379602 LOC105379602 - +105379603 LOC105379603 - +105379604 LOC105379604 - +105379605 LOC105379605 - +105379611 LOC105379611 - +105379613 LOC105379613 - +105379618 LOC105379618 - +105379623 LOC105379623 - +105379626 LOC105379626 - +105379627 LOC105379627 - +105379630 LOC105379630 - +105379631 LOC105379631 - +105379633 LOC105379633 - +105379634 LOC105379634 - +105379635 LOC105379635 - +105379638 LOC105379638 - +105379640 LOC105379640 - +105379641 LOC105379641 - +105379642 LOC105379642 - +105379655 LOC105379655 - +105379656 LOC105379656 - +105379657 LOC105379657 - +105379663 LOC105379663 - +105379664 LOC105379664 - +105379675 LOC105379675 - +105379683 LOC105379683 - +105379684 LOC105379684 - +105379685 LOC105379685 - +105379687 LOC105379687 - +105379695 LOC105379695 Ensembl:ENSG00000272273 +105379699 LOC105379699 - +105379700 LOC105379700 - +105379701 LOC105379701 - +105379709 LOC105379709 - +105379712 LOC105379712 - +105379715 LOC105379715 - +105379719 LOC105379719 - +105379720 LOC105379720 - +105379724 LOC105379724 - +105379725 LOC105379725 - +105379728 LOC105379728 - +105379729 LOC105379729 - +105379731 LOC105379731 - +105379733 LOC105379733 - +105379740 LOC105379740 - +105379743 LOC105379743 - +105379746 LOC105379746 - +105379749 LOC105379749 - +105379752 LOC105379752 - +105379755 LOC105379755 - +105379756 LOC105379756 - +105379758 LOC105379758 - +105379760 LOC105379760 - +105379762 LOC105379762 - +105379763 LOC105379763 - +105379764 LOC105379764 - +105379765 LOC105379765 - +105379769 LOC105379769 - +105379771 LOC105379771 - +105379772 LOC105379772 - +105379773 LOC105379773 - +105379775 LOC105379775 - +105379778 LOC105379778 - +105379783 LOC105379783 - +105379795 LOC105379795 - +105379797 LOC105379797 - +105379799 LOC105379799 - +105379801 LOC105379801 - +105379804 LOC105379804 - +105379805 LOC105379805 - +105379806 LOC105379806 - +105379807 LOC105379807 - +105379808 LOC105379808 - +105379809 LOC105379809 - +105379812 LOC105379812 - +105379813 LOC105379813 - +105379814 LOC105379814 - +105379815 LOC105379815 - +105379818 LOC105379818 - +105379820 LOC105379820 - +105379821 LOC105379821 - +105379823 LOC105379823 - +105379825 LOC105379825 - +105379827 LOC105379827 - +105379828 LOC105379828 - +105379829 LOC105379829 - +105379830 LOC105379830 - +105379839 LOC105379839 - +105379841 LOC105379841 - +105379843 LOC105379843 - +105379844 LOC105379844 - +105379849 LOC105379849 - +105379850 LOC105379850 - +105379854 LOC105379854 - +105379855 LOC105379855 - +105379857 LOC105379857 - +105379859 LOC105379859 - +105379861 LOC105379861 - +105379863 LOC105379863 - +105379865 LOC105379865 - +105379866 LOC105379866 - +105379869 LOC105379869 - +105379877 LOC105379877 - +105379880 LOC105379880 - +105379882 LOC105379882 - +105379884 LOC105379884 - +105416157 NKILA HGNC:HGNC:51599|Ensembl:ENSG00000278709 +105419997 SFTPD-AS1 HGNC:HGNC:51589 +105447645 LOC105447645 - +105447646 PNKY MIM:616328 +105447648 LINC02130 HGNC:HGNC:52989|Ensembl:ENSG00000260009 +105463123 XACT MIM:300901|HGNC:HGNC:45056|Ensembl:ENSG00000241743 +105463125 ATOD8 MIM:613518 +105463126 ATOD9 MIM:613519 +105463127 PFHB2 MIM:140400 +105463128 MRXSBWB MIM:300612 +105463129 MRX88 MIM:300852 +105500239 XLOC_007697 - +105500240 XLOC_009911 - +105616916 LINC01455 HGNC:HGNC:50545|Ensembl:ENSG00000250888 +105616981 LOC105616981 - +105616982 LINC01047 HGNC:HGNC:49041|Ensembl:ENSG00000232225 +105664404 WSPAR MIM:616333|HGNC:HGNC:51639|Ensembl:ENSG00000249073 +105667213 LINC01601 HGNC:HGNC:51651 +105682749 CCEPR HGNC:HGNC:51693 +105694156 ERVW-28 HGNC:HGNC:49316 +105747689 LOC105747689 - +105748977 LINC01693 HGNC:HGNC:52478 +105751187 LRP1-AS HGNC:HGNC:51694|Ensembl:ENSG00000259125 +105755953 LOC105755953 Ensembl:ENSG00000234752 +105755954 ADGRD1-AS1 HGNC:HGNC:53314 +105804841 ZRS - +105827617 LINC02563 HGNC:HGNC:52923|Ensembl:ENSG00000263520 +105941491 PAX6DRR - +105943583 LOC105943583 - +105943586 LOC105943586 - +105943587 LOC105943587 - +105980003 LOC105980003 - +105980005 LOC105980005 - +105980006 LOC105980006 - +105980008 LOC105980008 - +105980073 LOC105980073 - +105980078 LOC105980078 - +106003269 SRXY10 MIM:616425 +106007485 LOC106007485 - +106007490 LOC106007490 - +106007491 LOC106007491 - +106007493 LOC106007493 - +106010957 PAX6_HS8 - +106010958 HBB-HS-111 - +106014249 LOC106014249 - +106020709 LOC106020709 - +106020710 LOC106020710 - +106020711 LOC106020711 - +106020712 LOC106020712 - +106029238 PAX6_HS2 - +106029239 PAX6_HS3 - +106029240 LOC106029240 - +106029241 LOC106029241 - +106029242 LOC106029242 - +106029243 CREST1 - +106029244 CREST2 - +106029245 CREST3 - +106029310 DANT1 MIM:301001|HGNC:HGNC:50863 +106029311 LOC106029311 - +106029312 LOC106029312 - +106029313 LOC106029313 - +106049960 SBE2 - +106049962 LOC106049962 - +106050037 LOC106050037 - +106050102 LOC106050102 - +106050103 LOC106050103 - +106096416 LOC106096416 - +106099062 LOC106099062 - +106099063 LOC106099063 - +106099064 LOC106099064 - +106099065 LOC106099065 - +106099130 GSTT1-AS1 HGNC:HGNC:51839 +106113036 LOC106113036 - +106113037 LOC106113037 - +106128901 TH2-LCR - +106128902 LOC106128902 - +106128904 GH-LCR - +106128905 LOC106128905 - +106128906 LOC106128906 - +106144524 HUNK-AS1 HGNC:HGNC:40631 +106144526 PLA2G4C-AS1 HGNC:HGNC:51585|Ensembl:ENSG00000269420 +106144527 LINC01438 HGNC:HGNC:50757 +106144528 DENND6A-AS1 HGNC:HGNC:41152 +106144529 GRPEL2-AS1 HGNC:HGNC:48999|Ensembl:ENSG00000253618 +106144530 LINC01332 HGNC:HGNC:50540 +106144531 LINC00374 HGNC:HGNC:42698|Ensembl:ENSG00000232954 +106144532 ARF4-AS1 HGNC:HGNC:51593|Ensembl:ENSG00000272146 +106144533 LINC00430 HGNC:HGNC:42765 +106144534 BICRA-AS1 HGNC:HGNC:51588 +106144535 LINC01037 HGNC:HGNC:49025|Ensembl:ENSG00000231599 +106144536 LINC01078 HGNC:HGNC:49121 +106144537 LINC01173 HGNC:HGNC:49545|Ensembl:ENSG00000280744 +106144538 KCNK15-AS1 HGNC:HGNC:49901 +106144539 FOXD1-AS1 HGNC:HGNC:50658 +106144540 LINC01326 HGNC:HGNC:50532 +106144541 LINC00407 HGNC:HGNC:42739 +106144542 LINC01385 HGNC:HGNC:50657 +106144543 WISP1-OT1 HGNC:HGNC:49126 +106144544 LINC01066 HGNC:HGNC:49104 +106144555 ERVK-29 HGNC:HGNC:44982 +106144556 LOC106144556 - +106144557 LOC106144557 - +106144558 LOC106144558 - +106144559 ERVW-8 HGNC:HGNC:49247 +106144560 ERVW-11 HGNC:HGNC:49250 +106144561 ERVW-14 HGNC:HGNC:49253 +106144562 ERVW-18 HGNC:HGNC:49306 +106144563 ERVW-22 HGNC:HGNC:49310 +106144564 ERVW-24 HGNC:HGNC:49312 +106144565 ERVW-27 HGNC:HGNC:49315 +106144566 ERVK-27 HGNC:HGNC:44980 +106144567 ERVW-17 HGNC:HGNC:49256 +106144568 LINC01381 HGNC:HGNC:50653|Ensembl:ENSG00000230452 +106144571 ERVW-19 HGNC:HGNC:49307 +106144572 ERVW-26 HGNC:HGNC:49314 +106144573 HBA-LCR - +106144575 LINC01154 HGNC:HGNC:49504 +106144576 ERVW-13 HGNC:HGNC:49252 +106144578 LINC00604 HGNC:HGNC:43924 +106144579 ERVW-10 HGNC:HGNC:49249 +106144580 ERVW-12 HGNC:HGNC:49251 +106144581 ERVW-16 HGNC:HGNC:49255 +106144583 ERVW-29 HGNC:HGNC:49378 +106144584 LINC01290 HGNC:HGNC:50356 +106144585 LINC01318 HGNC:HGNC:50524|Ensembl:ENSG00000237790 +106144586 LINC01394 HGNC:HGNC:50670 +106144587 ERVW-21 HGNC:HGNC:49309 +106144589 ERVW-7 HGNC:HGNC:49246 +106144590 ERVK-31 HGNC:HGNC:51379 +106144591 ERVK-30 HGNC:HGNC:51378 +106144592 LINC01035 HGNC:HGNC:49022 +106144593 NOP53-AS1 HGNC:HGNC:51587|Ensembl:ENSG00000269656 +106144595 LINC01374 HGNC:HGNC:50631 +106144597 ERVW-15 HGNC:HGNC:49254 +106144598 FARSA-AS1 HGNC:HGNC:50479 +106144599 LINC01259 HGNC:HGNC:49899 +106144601 LINC01034 HGNC:HGNC:49021 +106144602 LINC01076 HGNC:HGNC:49119 +106144603 ERVW-23 HGNC:HGNC:49311 +106144604 ERVW-20 HGNC:HGNC:49308 +106144605 ERVW-25 HGNC:HGNC:49313 +106144606 CCND2-AS2 HGNC:HGNC:49399 +106144607 LINC01074 HGNC:HGNC:49117 +106144608 LINC00976 HGNC:HGNC:50610 +106144609 LOC106144609 - +106144610 LOC106144610 - +106146143 LOC106146143 - +106146144 LOC106146144 - +106146146 LINC01079 HGNC:HGNC:49122 +106146148 LINC01297 HGNC:HGNC:50443|Ensembl:ENSG00000225255 +106146149 LINC01613 HGNC:HGNC:51842|Ensembl:ENSG00000261432 +106146150 LOC106146150 - +106146151 LOC106146151 - +106146152 LOC106146152 - +106146153 LOC106146153 - +106182118 LIMS1-AS1 HGNC:HGNC:40342 +106182249 LUADT1 HGNC:HGNC:51845|Ensembl:ENSG00000196634 +106456574 LINC01616 HGNC:HGNC:51900|Ensembl:ENSG00000261340 +106478909 MTND4LP1 HGNC:HGNC:31347 +106478910 LAMTOR5P1 HGNC:HGNC:31854 +106478911 CST12P HGNC:HGNC:31920 +106478912 RNU6-41P HGNC:HGNC:34247 +106478913 RNU6-5P HGNC:HGNC:34249 +106478914 RNU6-4P HGNC:HGNC:34253 +106478915 RNU6-11P HGNC:HGNC:34255 +106478916 RNU6-18P HGNC:HGNC:34262 +106478917 RNU6-22P HGNC:HGNC:34266 +106478918 RNU6-27P HGNC:HGNC:34271 +106478919 RNU6-3P HGNC:HGNC:34275 +106478920 RNU6-37P HGNC:HGNC:34281 +106478921 RNU6-43P HGNC:HGNC:34287 +106478922 RNU6-44P HGNC:HGNC:34288 +106478923 RNU6-49P HGNC:HGNC:34293 +106478924 DHRSX-IT1 HGNC:HGNC:38713 +106478925 KRT18P53 HGNC:HGNC:38714 +106478926 DPH3P2 HGNC:HGNC:38719 +106478927 USP9YP16 HGNC:HGNC:38752 +106478928 USP9YP24 HGNC:HGNC:38760 +106478929 USP9YP26 HGNC:HGNC:38762 +106478930 USP9YP31 HGNC:HGNC:38775 +106478931 USP9YP33 HGNC:HGNC:38777 +106478932 USP9YP36 HGNC:HGNC:38780 +106478933 PRYP5 HGNC:HGNC:38785 +106478934 HSFY5P HGNC:HGNC:38789 +106478935 HSFY7P HGNC:HGNC:38791 +106478936 FTH1P9 HGNC:HGNC:39089 +106478937 TPM3P3 HGNC:HGNC:39166 +106478938 OOEP-AS1 HGNC:HGNC:39192 +106478939 PHBP5 HGNC:HGNC:39284 +106478940 PHBP6 HGNC:HGNC:39285 +106478941 MTND6P2 HGNC:HGNC:39465 +106478942 MTND6P3 HGNC:HGNC:39466 +106478943 MTND6P4 HGNC:HGNC:39467 +106478944 MTND6P6 HGNC:HGNC:39469 +106478945 MTND6P7 HGNC:HGNC:39470 +106478946 MTND6P9 HGNC:HGNC:39472 +106478947 MTND6P10 HGNC:HGNC:39473 +106478948 MTND6P14 HGNC:HGNC:39477 +106478949 MTND6P15 HGNC:HGNC:39478 +106478950 MTND6P16 HGNC:HGNC:39479 +106478951 MTND6P18 HGNC:HGNC:39481 +106478952 MTND6P20 HGNC:HGNC:39483 +106478953 RBM22P7 HGNC:HGNC:39700 +106478954 EHMT2-AS1 HGNC:HGNC:39751 +106478955 C4A-AS1 HGNC:HGNC:39753 +106478956 MDC1-AS1 HGNC:HGNC:39764|Ensembl:ENSG00000224328 +106478957 DDX39B-AS1 HGNC:HGNC:39771|Ensembl:ENSG00000234006 +106478958 CYP4F26P HGNC:HGNC:39948 +106478959 CYP2C56P HGNC:HGNC:39971 +106478960 CYP2AC1P HGNC:HGNC:39976 +106478961 ATP6V0CP2 HGNC:HGNC:40000 +106478962 BACH1-AS1 HGNC:HGNC:40008 +106478963 BSN-AS1 HGNC:HGNC:40102 +106478964 CACNA1C-AS3 HGNC:HGNC:40117 +106478965 IGBP1-AS2 HGNC:HGNC:40294 +106478966 RRM1-AS1 HGNC:HGNC:40512 +106478967 SEC62-AS1 HGNC:HGNC:40586 +106478968 TRPC7-AS2 HGNC:HGNC:40937|Ensembl:ENSG00000250947 +106478969 DPP10-AS2 HGNC:HGNC:40940 +106478970 HTR3E-AS1 HGNC:HGNC:41032|Ensembl:ENSG00000238020 +106478971 ALG13-AS1 HGNC:HGNC:41277 +106478973 FMR1-IT1 HGNC:HGNC:41333 +106478974 REV3L-IT1 HGNC:HGNC:41377 +106478975 SMYD3-IT1 HGNC:HGNC:41406 +106478976 ASH1L-IT1 HGNC:HGNC:41449 +106478977 WWTR1-IT1 HGNC:HGNC:41469 +106478978 FAR1-IT1 HGNC:HGNC:41485 +106478979 A2ML1-AS2 HGNC:HGNC:41523 +106478980 RNU1-23P HGNC:HGNC:41964 +106478981 TUBB4BP1 HGNC:HGNC:42180 +106478982 TUBB8P2 HGNC:HGNC:42334 +106478983 CYP3A52P HGNC:HGNC:42412 +106478984 RNY3P1 HGNC:HGNC:42477 +106478985 RNY3P8 HGNC:HGNC:42492 +106478986 RNU6-54P HGNC:HGNC:42544 +106478987 RNU6-62P HGNC:HGNC:42552 +106478988 RNU6-70P HGNC:HGNC:42560 +106478989 RNU6-73P HGNC:HGNC:42563 +106478990 RNU6-80P HGNC:HGNC:42570 +106478991 LINC00449 HGNC:HGNC:42786|Ensembl:ENSG00000203441 +106478992 RNA5SP50 HGNC:HGNC:42827 +106478993 RNA5SP99 HGNC:HGNC:42897 +106478994 RNA5SP106 HGNC:HGNC:42904 +106478995 RNA5SP130 HGNC:HGNC:43030 +106478996 RNA5SP140 HGNC:HGNC:43040 +106478997 RNA5SP172 HGNC:HGNC:43072 +106478998 RNA5SP174 HGNC:HGNC:43074 +106478999 RNA5SP206 HGNC:HGNC:43106 +106479000 RNA5SP226 HGNC:HGNC:43126 +106479001 RNA5SP243 HGNC:HGNC:43143 +106479002 RNA5SP263 HGNC:HGNC:43163 +106479003 RNA5SP297 HGNC:HGNC:43197 +106479004 RNA5SP302 HGNC:HGNC:43202 +106479005 RNA5SP315 HGNC:HGNC:43215 +106479006 RNA5SP317 HGNC:HGNC:43217 +106479007 RNA5SP335 HGNC:HGNC:43235 +106479008 RNA5SP342 HGNC:HGNC:43242 +106479009 RNA5SP355 HGNC:HGNC:43255 +106479010 RNA5SP376 HGNC:HGNC:43276 +106479011 RNA5SP377 HGNC:HGNC:43277 +106479012 RNA5SP403 HGNC:HGNC:43303 +106479013 RNA5SP435 HGNC:HGNC:43335 +106479014 RNA5SP439 HGNC:HGNC:43339 +106479015 RNA5SP448 HGNC:HGNC:43348 +106479016 RNA5SP458 HGNC:HGNC:43358 +106479017 RNA5SP473 HGNC:HGNC:43373 +106479018 RNA5SP521 HGNC:HGNC:43421 +106479019 RNA5SP522 HGNC:HGNC:43422 +106479020 WASHC5-AS1 HGNC:HGNC:43440 +106479021 CHEK2P4 HGNC:HGNC:43580 +106479022 CHEK2P5 HGNC:HGNC:43581 +106479023 HIST2H3DP1 HGNC:HGNC:43797 +106479024 LRRC37A13P HGNC:HGNC:43817 +106479025 LRRC37A14P HGNC:HGNC:43818 +106479026 NECAP1P2 HGNC:HGNC:43913 +106479027 KRT18P56 HGNC:HGNC:43923 +106479028 AIG1P1 HGNC:HGNC:43926 +106479029 WBP1LP1 HGNC:HGNC:43948 +106479030 WBP1LP7 HGNC:HGNC:43955 +106479031 WBP1LP3 HGNC:HGNC:43958 +106479032 PQLC1P1 HGNC:HGNC:43986 +106479033 TRMT112P2 HGNC:HGNC:44021 +106479034 LARP1BP2 HGNC:HGNC:44084 +106479035 GZMAP1 HGNC:HGNC:44137 +106479036 EIF1AXP2 HGNC:HGNC:44295 +106479037 ALG1L10P HGNC:HGNC:44379 +106479038 ALG1L13P HGNC:HGNC:44382 +106479039 CHCHD4P5 HGNC:HGNC:44493 +106479040 CRIP1P3 HGNC:HGNC:44518 +106479041 TUBAP4 HGNC:HGNC:44569 +106479042 MTATP8P2 HGNC:HGNC:44572 +106479043 MTATP6P3 HGNC:HGNC:44577 +106479044 MTATP6P9 HGNC:HGNC:44583 +106479045 FCF1P5 HGNC:HGNC:44617 +106479046 FCF1P10 HGNC:HGNC:44622 +106479047 EFCAB14P1 HGNC:HGNC:44648 +106479048 UBE2V1P12 HGNC:HGNC:44897 +106479049 NIFKP7 HGNC:HGNC:44955 +106479050 KSR1P1 HGNC:HGNC:44977 +106479051 NDUFA3P2 HGNC:HGNC:45051 +106479052 NDUFA3P6 HGNC:HGNC:45055 +106479053 MED28P5 HGNC:HGNC:45082 +106479054 TMEM256P2 HGNC:HGNC:45088 +106479055 SOD1P1 HGNC:HGNC:45134 +106479056 PIGPP2 HGNC:HGNC:45154 +106479057 FABP12P1 HGNC:HGNC:45176 +106479058 COPS8P3 HGNC:HGNC:45271 +106479059 OLA1P2 HGNC:HGNC:45277 +106479060 RNU7-90P HGNC:HGNC:45624 +106479061 RNU7-92P HGNC:HGNC:45626 +106479062 RNU7-95P HGNC:HGNC:45629 +106479063 RNU7-97P HGNC:HGNC:45631 +106479064 RNU7-102P HGNC:HGNC:45636 +106479065 RNU7-105P HGNC:HGNC:45639 +106479066 RNU7-106P HGNC:HGNC:45640 +106479067 RNU7-107P HGNC:HGNC:45641 +106479068 RNU7-113P HGNC:HGNC:45647 +106479069 RNU7-115P HGNC:HGNC:45649 +106479070 RNU7-119P HGNC:HGNC:45653 +106479071 RNU7-123P HGNC:HGNC:45657 +106479072 RNU7-124P HGNC:HGNC:45658 +106479073 RNU7-126P HGNC:HGNC:45660 +106479074 RNU7-130P HGNC:HGNC:45664 +106479075 RNU7-133P HGNC:HGNC:45667 +106479076 RNU7-136P HGNC:HGNC:45670 +106479077 RNU7-140P HGNC:HGNC:45674 +106479078 RNU7-143P HGNC:HGNC:45677 +106479079 RNU7-144P HGNC:HGNC:45678 +106479080 RNU7-149P HGNC:HGNC:45683 +106479081 RNU7-152P HGNC:HGNC:45686 +106479082 RNU7-153P HGNC:HGNC:45687 +106479083 RNU7-156P HGNC:HGNC:45690 +106479085 RNU7-160P HGNC:HGNC:45694 +106479086 RNU7-164P HGNC:HGNC:45698 +106479087 RNU7-165P HGNC:HGNC:45699 +106479088 RNU7-167P HGNC:HGNC:45701 +106479089 RNU7-171P HGNC:HGNC:45705 +106479090 RNU7-173P HGNC:HGNC:45707 +106479091 RNU7-175P HGNC:HGNC:45709 +106479092 RNU7-179P HGNC:HGNC:45713 +106479093 RNU7-181P HGNC:HGNC:45715 +106479094 RNU7-185P HGNC:HGNC:45719 +106479095 RNU7-187P HGNC:HGNC:45721 +106479096 RNU7-190P HGNC:HGNC:45724 +106479097 RNU7-195P HGNC:HGNC:45729 +106479098 RNU7-196P HGNC:HGNC:45730 +106479099 RN7SKP11 HGNC:HGNC:45735 +106479100 RN7SKP13 HGNC:HGNC:45737 +106479101 RN7SKP14 HGNC:HGNC:45738 +106479102 RN7SKP17 HGNC:HGNC:45741 +106479103 RN7SKP19 HGNC:HGNC:45743 +106479104 RN7SKP20 HGNC:HGNC:45744 +106479105 RN7SKP23 HGNC:HGNC:45747 +106479106 RN7SKP26 HGNC:HGNC:45750 +106479107 RN7SKP28 HGNC:HGNC:45752 +106479108 RN7SKP30 HGNC:HGNC:45754 +106479109 RN7SKP32 HGNC:HGNC:45756 +106479110 RN7SKP34 HGNC:HGNC:45758 +106479111 RN7SKP35 HGNC:HGNC:45759 +106479112 RN7SKP38 HGNC:HGNC:45762 +106479113 RN7SKP40 HGNC:HGNC:45764 +106479114 RN7SKP44 HGNC:HGNC:45768 +106479115 RN7SKP45 HGNC:HGNC:45769 +106479116 RN7SKP48 HGNC:HGNC:45772 +106479117 RN7SKP51 HGNC:HGNC:45775 +106479118 RN7SKP52 HGNC:HGNC:45776 +106479119 RN7SKP55 HGNC:HGNC:45779 +106479120 RN7SKP57 HGNC:HGNC:45781 +106479121 RN7SKP59 HGNC:HGNC:45783 +106479122 RN7SKP61 HGNC:HGNC:45785 +106479123 RN7SKP63 HGNC:HGNC:45787 +106479124 RN7SKP65 HGNC:HGNC:45789 +106479125 RN7SKP67 HGNC:HGNC:45791 +106479126 RN7SKP71 HGNC:HGNC:45795 +106479127 RN7SKP74 HGNC:HGNC:45798 +106479128 RN7SKP77 HGNC:HGNC:45801 +106479129 RN7SKP78 HGNC:HGNC:45802 +106479130 RN7SKP80 HGNC:HGNC:45804 +106479131 RN7SKP83 HGNC:HGNC:45807 +106479132 RN7SKP85 HGNC:HGNC:45809 +106479133 RN7SKP87 HGNC:HGNC:45811 +106479134 RN7SKP89 HGNC:HGNC:45813 +106479135 RN7SKP92 HGNC:HGNC:45816 +106479136 RN7SKP93 HGNC:HGNC:45817 +106479137 RN7SKP96 HGNC:HGNC:45820 +106479138 RN7SKP99 HGNC:HGNC:45823 +106479139 RN7SKP100 HGNC:HGNC:45824 +106479140 RN7SKP103 HGNC:HGNC:45827 +106479141 RN7SKP105 HGNC:HGNC:45829 +106479142 RN7SKP106 HGNC:HGNC:45830 +106479143 RN7SKP109 HGNC:HGNC:45833 +106479144 RN7SKP111 HGNC:HGNC:45835 +106479145 RN7SKP112 HGNC:HGNC:45836 +106479146 RN7SKP115 HGNC:HGNC:45839 +106479147 RN7SKP117 HGNC:HGNC:45841 +106479148 RN7SKP122 HGNC:HGNC:45846 +106479149 RN7SKP123 HGNC:HGNC:45847 +106479150 RN7SKP125 HGNC:HGNC:45849 +106479151 RN7SKP128 HGNC:HGNC:45852 +106479152 RN7SKP129 HGNC:HGNC:45853 +106479153 RN7SKP131 HGNC:HGNC:45855 +106479154 RN7SKP134 HGNC:HGNC:45858 +106479155 RN7SKP136 HGNC:HGNC:45860 +106479156 RN7SKP137 HGNC:HGNC:45861 +106479157 RN7SKP141 HGNC:HGNC:45865 +106479158 RN7SKP143 HGNC:HGNC:45867 +106479159 RN7SKP144 HGNC:HGNC:45868 +106479160 RN7SKP146 HGNC:HGNC:45870 +106479161 RN7SKP149 HGNC:HGNC:45873 +106479162 RN7SKP151 HGNC:HGNC:45875 +106479163 RN7SKP152 HGNC:HGNC:45876 +106479164 RN7SKP155 HGNC:HGNC:45879 +106479165 RN7SKP157 HGNC:HGNC:45881 +106479166 RN7SKP160 HGNC:HGNC:45884 +106479167 RN7SKP161 HGNC:HGNC:45885 +106479168 RN7SKP163 HGNC:HGNC:45887 +106479169 RN7SKP167 HGNC:HGNC:45891 +106479170 RN7SKP168 HGNC:HGNC:45892 +106479171 RN7SKP170 HGNC:HGNC:45894 +106479172 RN7SKP174 HGNC:HGNC:45898 +106479173 RN7SKP175 HGNC:HGNC:45899 +106479174 RN7SKP177 HGNC:HGNC:45901 +106479175 RN7SKP178 HGNC:HGNC:45902 +106479176 RN7SKP181 HGNC:HGNC:45905 +106479177 RN7SKP182 HGNC:HGNC:45906 +106479178 RN7SKP185 HGNC:HGNC:45909 +106479179 RN7SKP188 HGNC:HGNC:45912 +106479180 RN7SKP189 HGNC:HGNC:45913 +106479181 RN7SKP193 HGNC:HGNC:45917 +106479182 RN7SKP196 HGNC:HGNC:45920 +106479183 RN7SKP198 HGNC:HGNC:45922 +106479184 RN7SKP199 HGNC:HGNC:45923 +106479185 RN7SKP203 HGNC:HGNC:45927 +106479186 RN7SKP205 HGNC:HGNC:45929 +106479187 RN7SKP206 HGNC:HGNC:45930 +106479188 RN7SKP209 HGNC:HGNC:45933 +106479189 RN7SKP211 HGNC:HGNC:45935 +106479190 RN7SKP216 HGNC:HGNC:45940 +106479191 RN7SKP217 HGNC:HGNC:45941 +106479192 RN7SKP219 HGNC:HGNC:45943 +106479193 RN7SKP222 HGNC:HGNC:45946 +106479194 RN7SKP223 HGNC:HGNC:45947 +106479195 RN7SKP225 HGNC:HGNC:45949 +106479196 RN7SKP228 HGNC:HGNC:45952 +106479197 RN7SKP230 HGNC:HGNC:45954 +106479198 RN7SKP231 HGNC:HGNC:45955 +106479199 RN7SKP235 HGNC:HGNC:45959 +106479200 RN7SKP237 HGNC:HGNC:45961 +106479201 RN7SKP238 HGNC:HGNC:45962 +106479202 RN7SKP240 HGNC:HGNC:45964 +106479203 RN7SKP244 HGNC:HGNC:45968 +106479204 RN7SKP246 HGNC:HGNC:45970 +106479205 RN7SKP247 HGNC:HGNC:45971 +106479206 RN7SKP250 HGNC:HGNC:45974 +106479207 RN7SKP252 HGNC:HGNC:45976 +106479208 RN7SKP253 HGNC:HGNC:45977 +106479209 RN7SKP255 HGNC:HGNC:45979 +106479210 RN7SKP257 HGNC:HGNC:45981 +106479211 RN7SKP260 HGNC:HGNC:45984 +106479212 RN7SKP262 HGNC:HGNC:45986 +106479213 RN7SKP264 HGNC:HGNC:45988 +106479214 RN7SKP266 HGNC:HGNC:45990 +106479215 RN7SKP268 HGNC:HGNC:45992 +106479216 RN7SKP270 HGNC:HGNC:45994 +106479217 RN7SKP272 HGNC:HGNC:45996 +106479218 RN7SKP276 HGNC:HGNC:46000 +106479219 RN7SKP277 HGNC:HGNC:46001 +106479220 RN7SKP280 HGNC:HGNC:46004 +106479221 RN7SKP283 HGNC:HGNC:46007 +106479222 RN7SKP284 HGNC:HGNC:46008 +106479223 RN7SKP288 HGNC:HGNC:46012 +106479224 RN7SKP289 HGNC:HGNC:46013 +106479225 RN7SKP292 HGNC:HGNC:46016 +106479226 RN7SKP294 HGNC:HGNC:46018 +106479227 RN7SKP297 HGNC:HGNC:46021 +106479228 RN7SKP298 HGNC:HGNC:46022 +106479229 RN7SL11P HGNC:HGNC:46027 +106479230 RN7SL15P HGNC:HGNC:46031 +106479231 RN7SL16P HGNC:HGNC:46032 +106479232 RN7SL20P HGNC:HGNC:46036 +106479233 RN7SL25P HGNC:HGNC:46041 +106479234 RN7SL26P HGNC:HGNC:46042 +106479235 RN7SL30P HGNC:HGNC:46046 +106479236 RN7SL33P HGNC:HGNC:46049 +106479237 RN7SL36P HGNC:HGNC:46052 +106479238 RN7SL37P HGNC:HGNC:46053 +106479239 RN7SL39P HGNC:HGNC:46055 +106479240 RN7SL42P HGNC:HGNC:46058 +106479241 RN7SL43P HGNC:HGNC:46059 +106479242 RN7SL47P HGNC:HGNC:46063 +106479243 RN7SL50P HGNC:HGNC:46066 +106479244 RN7SL55P HGNC:HGNC:46071 +106479245 RN7SL58P HGNC:HGNC:46074 +106479246 RN7SL62P HGNC:HGNC:46078 +106479247 RN7SL65P HGNC:HGNC:46081 +106479248 RN7SL67P HGNC:HGNC:46083 +106479249 RN7SL70P HGNC:HGNC:46086 +106479250 RN7SL73P HGNC:HGNC:46089 +106479251 RN7SL76P HGNC:HGNC:46092 +106479252 RN7SL77P HGNC:HGNC:46093 +106479253 RN7SL81P HGNC:HGNC:46097 +106479254 RN7SL83P HGNC:HGNC:46099 +106479255 RN7SL87P HGNC:HGNC:46103 +106479256 RN7SL89P HGNC:HGNC:46105 +106479257 RN7SL92P HGNC:HGNC:46108 +106479258 RN7SL97P HGNC:HGNC:46113 +106479259 RN7SL98P HGNC:HGNC:46114 +106479260 RN7SL101P HGNC:HGNC:46117 +106479261 RN7SL106P HGNC:HGNC:46122 +106479262 RN7SL107P HGNC:HGNC:46123 +106479263 RN7SL111P HGNC:HGNC:46127 +106479264 RN7SL117P HGNC:HGNC:46133 +106479265 RN7SL121P HGNC:HGNC:46137 +106479266 RN7SL123P HGNC:HGNC:46139 +106479267 RN7SL125P HGNC:HGNC:46141 +106479268 RN7SL126P HGNC:HGNC:46142 +106479269 RN7SL130P HGNC:HGNC:46146 +106479270 RN7SL132P HGNC:HGNC:46148 +106479271 RN7SL134P HGNC:HGNC:46150 +106479272 RN7SL140P HGNC:HGNC:46156 +106479273 RN7SL143P HGNC:HGNC:46159 +106479274 RN7SL147P HGNC:HGNC:46163 +106479275 RN7SL148P HGNC:HGNC:46164 +106479276 RN7SL150P HGNC:HGNC:46166 +106479277 RN7SL154P HGNC:HGNC:46170 +106479278 RN7SL155P HGNC:HGNC:46171 +106479279 RN7SL159P HGNC:HGNC:46175 +106479280 RN7SL163P HGNC:HGNC:46179 +106479281 RN7SL165P HGNC:HGNC:46181 +106479282 RN7SL166P HGNC:HGNC:46182 +106479283 RN7SL170P HGNC:HGNC:46186 +106479284 RN7SL173P HGNC:HGNC:46189 +106479285 RN7SL174P HGNC:HGNC:46190 +106479286 RN7SL178P HGNC:HGNC:46194 +106479287 RN7SL182P HGNC:HGNC:46198 +106479288 RN7SL184P HGNC:HGNC:46200 +106479289 RN7SL185P HGNC:HGNC:46201 +106479290 RN7SL188P HGNC:HGNC:46204 +106479291 RN7SL190P HGNC:HGNC:46206 +106479292 RN7SL191P HGNC:HGNC:46207 +106479293 RN7SL196P HGNC:HGNC:46212 +106479294 RN7SL198P HGNC:HGNC:46214 +106479295 RN7SL202P HGNC:HGNC:46218 +106479296 RN7SL203P HGNC:HGNC:46219 +106479297 RN7SL205P HGNC:HGNC:46221 +106479298 RN7SL210P HGNC:HGNC:46226 +106479299 RN7SL211P HGNC:HGNC:46227 +106479300 RN7SL214P HGNC:HGNC:46230 +106479301 RN7SL217P HGNC:HGNC:46233 +106479302 RN7SL219P HGNC:HGNC:46235 +106479303 RN7SL220P HGNC:HGNC:46236 +106479304 RN7SL225P HGNC:HGNC:46241 +106479305 RN7SL229P HGNC:HGNC:46245 +106479306 RN7SL230P HGNC:HGNC:46246 +106479307 RN7SL234P HGNC:HGNC:46250 +106479308 RN7SL237P HGNC:HGNC:46253 +106479309 RN7SL239P HGNC:HGNC:46255 +106479310 RN7SL240P HGNC:HGNC:46256 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HGNC:HGNC:48042 +106480041 RNU6-1082P HGNC:HGNC:48045 +106480042 RNU6-1084P HGNC:HGNC:48047 +106480043 RNU6-1085P HGNC:HGNC:48048 +106480044 RNU6-1088P HGNC:HGNC:48051 +106480045 RNU6-1090P HGNC:HGNC:48053 +106480046 RNU6-1092P HGNC:HGNC:48055 +106480047 RNU6-1094P HGNC:HGNC:48057 +106480048 RNU6-1097P HGNC:HGNC:48060 +106480049 RNU6-1100P HGNC:HGNC:48063 +106480050 RNU6-1101P HGNC:HGNC:48064 +106480051 RNU6-1103P HGNC:HGNC:48066 +106480052 RNU6-1105P HGNC:HGNC:48068 +106480053 RNU6-1106P HGNC:HGNC:48069 +106480054 RNU6-1109P HGNC:HGNC:48072 +106480055 RNU6-1112P HGNC:HGNC:48075 +106480056 RNU6-1113P HGNC:HGNC:48076 +106480057 RNU6-1116P HGNC:HGNC:48079 +106480058 RNU6-1118P HGNC:HGNC:48081 +106480059 RNU6-1120P HGNC:HGNC:48083 +106480060 RNU6-1123P HGNC:HGNC:48086 +106480061 RNU6-1125P HGNC:HGNC:48088 +106480062 RNU6-1128P HGNC:HGNC:48091 +106480063 RNU6-1130P HGNC:HGNC:48093 +106480064 RNU6-1131P HGNC:HGNC:48094 +106480065 RNU6-1134P HGNC:HGNC:48097 +106480066 RNU6-1136P HGNC:HGNC:48099 +106480067 RNU6-1137P HGNC:HGNC:48100 +106480068 RNU6-1140P HGNC:HGNC:48103 +106480069 RNU6-1143P HGNC:HGNC:48106 +106480070 RNU6-1146P HGNC:HGNC:48109 +106480071 RNU6-1147P HGNC:HGNC:48110 +106480072 RNU6-1150P HGNC:HGNC:48113 +106480073 RNU6-1152P HGNC:HGNC:48115 +106480074 RNU6-1154P HGNC:HGNC:48117 +106480075 RNU6-1156P HGNC:HGNC:48119 +106480076 RNU6-1158P HGNC:HGNC:48121 +106480077 RNU6-1161P HGNC:HGNC:48124 +106480078 RNU6-1162P HGNC:HGNC:48125 +106480079 RNU6-1165P HGNC:HGNC:48128 +106480080 RNU6-1169P HGNC:HGNC:48132 +106480081 RNU6-1170P HGNC:HGNC:48133 +106480082 RNU6-1175P HGNC:HGNC:48138 +106480083 RNU6-1178P HGNC:HGNC:48141 +106480084 RNU6-1179P HGNC:HGNC:48142 +106480085 RNU6-1181P HGNC:HGNC:48144 +106480086 RNU6-1186P HGNC:HGNC:48149 +106480087 RNU6-1190P HGNC:HGNC:48153 +106480088 RNU6-1192P HGNC:HGNC:48155 +106480089 RNU6-1196P HGNC:HGNC:48159 +106480090 RNU6-1198P HGNC:HGNC:48161 +106480091 RNU6-1199P HGNC:HGNC:48162 +106480092 RNU6-1203P HGNC:HGNC:48166 +106480093 RNU6-1205P HGNC:HGNC:48168 +106480094 RNU6-1208P HGNC:HGNC:48171 +106480095 RNU6-1209P HGNC:HGNC:48172 +106480096 RNU6-1211P HGNC:HGNC:48174 +106480097 RNU6-1215P HGNC:HGNC:48178 +106480098 RNU6-1216P HGNC:HGNC:48179 +106480099 RNU6-1218P HGNC:HGNC:48181 +106480100 RNU6-1222P HGNC:HGNC:48185 +106480101 RNU6-1224P HGNC:HGNC:48187 +106480102 RNU6-1226P HGNC:HGNC:48189 +106480103 RNU6-1228P HGNC:HGNC:48191 +106480104 RNU6-1231P HGNC:HGNC:48194 +106480105 RNU6-1232P HGNC:HGNC:48195 +106480106 RNU6-1234P HGNC:HGNC:48197 +106480107 RNU6-1238P HGNC:HGNC:48201 +106480108 RNU6-1242P HGNC:HGNC:48205 +106480109 RNU6-1245P HGNC:HGNC:48208 +106480110 RNU6-1246P HGNC:HGNC:48209 +106480111 RNU6-1248P HGNC:HGNC:48211 +106480112 RNU6-1251P HGNC:HGNC:48214 +106480113 RNU6-1252P HGNC:HGNC:48215 +106480114 RNU6-1256P HGNC:HGNC:48219 +106480115 RNU6-1258P HGNC:HGNC:48221 +106480116 RNU6-1261P HGNC:HGNC:48224 +106480117 RNU6-1264P HGNC:HGNC:48227 +106480118 RNU6-1266P HGNC:HGNC:48229 +106480119 RNU6-1269P HGNC:HGNC:48232 +106480120 RNU6-1271P HGNC:HGNC:48234 +106480121 RNU6-1272P HGNC:HGNC:48235 +106480122 RNU6-1275P HGNC:HGNC:48238 +106480123 RNU6-1277P HGNC:HGNC:48240 +106480124 RNU6-1278P HGNC:HGNC:48241 +106480125 RNU6-1281P HGNC:HGNC:48244 +106480126 RNU6-1284P HGNC:HGNC:48247 +106480127 RNU6-1287P HGNC:HGNC:48250 +106480128 RNU6-1288P HGNC:HGNC:48251 +106480129 RNU6-1290P HGNC:HGNC:48253 +106480130 RNU6-1293P HGNC:HGNC:48256 +106480131 RNU6-1294P HGNC:HGNC:48257 +106480132 RNU6-1296P HGNC:HGNC:48259 +106480133 RNU6-1299P HGNC:HGNC:48262 +106480134 RNU6-1300P HGNC:HGNC:48263 +106480135 RNU6-1304P HGNC:HGNC:48267 +106480136 RNU6-1306P HGNC:HGNC:48269 +106480137 RNU6-1308P HGNC:HGNC:48271 +106480138 RNU6-1311P HGNC:HGNC:48274 +106480139 RNU6-1313P HGNC:HGNC:48276 +106480140 RNU6-1316P HGNC:HGNC:48279 +106480141 RNU6-1318P HGNC:HGNC:48281 +106480142 RNU6-1319P HGNC:HGNC:48282 +106480143 RNU6-1322P HGNC:HGNC:48285 +106480144 RNU6-1324P HGNC:HGNC:48287 +106480145 RNU6-1325P HGNC:HGNC:48288 +106480146 RNU6-1328P HGNC:HGNC:48291 +106480147 RNU6-1331P HGNC:HGNC:48294 +106480148 RNU6-1334P HGNC:HGNC:48297 +106480149 RNU6-1335P HGNC:HGNC:48298 +106480150 RNU6-1338P HGNC:HGNC:48301 +106480151 RNU6-1340P HGNC:HGNC:48303 +106480152 RNU1-6P HGNC:HGNC:48305 +106480153 RPS4XP23 HGNC:HGNC:48367 +106480154 RNU1-29P HGNC:HGNC:48371 +106480155 RNU1-32P HGNC:HGNC:48374 +106480156 RNU1-33P HGNC:HGNC:48375 +106480157 RNU1-35P HGNC:HGNC:48377 +106480158 RNU1-40P HGNC:HGNC:48382 +106480159 RNU1-43P HGNC:HGNC:48385 +106480160 RNU1-44P HGNC:HGNC:48386 +106480161 RNU1-47P HGNC:HGNC:48389 +106480162 RNU1-49P HGNC:HGNC:48391 +106480163 RNU1-51P HGNC:HGNC:48393 +106480164 RNU1-52P HGNC:HGNC:48394 +106480165 RNU1-56P HGNC:HGNC:48398 +106480166 RNU1-57P HGNC:HGNC:48399 +106480167 RNU1-59P HGNC:HGNC:48401 +106480168 RNU1-64P HGNC:HGNC:48406 +106480169 RNU1-67P HGNC:HGNC:48409 +106480171 RNU1-74P HGNC:HGNC:48416 +106480172 RNU1-75P HGNC:HGNC:48417 +106480173 RNU1-77P HGNC:HGNC:48419 +106480174 RNU1-80P HGNC:HGNC:48422 +106480175 RNU1-82P HGNC:HGNC:48424 +106480176 RNU1-83P HGNC:HGNC:48425 +106480177 RNU1-85P HGNC:HGNC:48427 +106480178 RNU1-87P HGNC:HGNC:48429 +106480179 RNU1-91P HGNC:HGNC:48433 +106480180 RNU1-93P HGNC:HGNC:48435 +106480181 RNU1-96P HGNC:HGNC:48438 +106480182 RNU1-97P HGNC:HGNC:48439 +106480183 RNU1-100P HGNC:HGNC:48442 +106480184 RNU1-104P HGNC:HGNC:48446 +106480185 RNU1-105P HGNC:HGNC:48447 +106480186 RNU1-107P HGNC:HGNC:48449 +106480187 RNU1-112P HGNC:HGNC:48454 +106480188 RNU1-115P HGNC:HGNC:48457 +106480189 RNU1-117P HGNC:HGNC:48459 +106480190 RNU1-122P HGNC:HGNC:48464 +106480191 RNU1-128P HGNC:HGNC:48470 +106480192 RNU1-130P HGNC:HGNC:48472 +106480193 RNU1-131P HGNC:HGNC:48473 +106480194 RNU1-134P HGNC:HGNC:48476 +106480195 RNU1-138P HGNC:HGNC:48480 +106480196 RNU1-139P HGNC:HGNC:48481 +106480197 RNU1-142P HGNC:HGNC:48484 +106480198 RNU1-146P HGNC:HGNC:48488 +106480199 RPL3P13 HGNC:HGNC:48494 +106480200 RNU2-8P HGNC:HGNC:48501 +106480201 RNU2-10P HGNC:HGNC:48503 +106480202 RNU2-12P HGNC:HGNC:48505 +106480203 RNU2-13P HGNC:HGNC:48506 +106480204 RNU2-17P HGNC:HGNC:48510 +106480205 RNU2-18P HGNC:HGNC:48511 +106480206 RNU2-21P HGNC:HGNC:48514 +106480207 RNU2-24P HGNC:HGNC:48517 +106480208 RNU2-25P HGNC:HGNC:48518 +106480209 RNU2-29P HGNC:HGNC:48522 +106480210 RNU2-31P HGNC:HGNC:48524 +106480211 RNU2-33P HGNC:HGNC:48526 +106480212 RNU2-35P HGNC:HGNC:48528 +106480213 RNU2-37P HGNC:HGNC:48530 +106480214 RNU2-39P HGNC:HGNC:48532 +106480215 RNU2-41P HGNC:HGNC:48534 +106480216 RNU2-43P HGNC:HGNC:48536 +106480217 RNU2-45P HGNC:HGNC:48538 +106480218 RNU2-46P HGNC:HGNC:48539 +106480219 RNU2-49P HGNC:HGNC:48542 +106480220 RNU2-53P HGNC:HGNC:48546 +106480221 RNU2-56P HGNC:HGNC:48549 +106480222 RNU2-57P HGNC:HGNC:48550 +106480223 RNU2-59P HGNC:HGNC:48552 +106480224 RNU2-62P HGNC:HGNC:48555 +106480225 RNU2-63P HGNC:HGNC:48556 +106480226 RNU2-65P HGNC:HGNC:48558 +106480227 RNU2-70P HGNC:HGNC:48563 +106480228 RNU2-71P HGNC:HGNC:48564 +106480229 MED15P8 HGNC:HGNC:48657 +106480230 ENPP7P12 HGNC:HGNC:48697 +106480231 RARRES2P5 HGNC:HGNC:48704 +106480232 OSBPL9P5 HGNC:HGNC:48735 +106480233 HNRNPH3P1 HGNC:HGNC:48750 +106480234 HNRNPA3P15 HGNC:HGNC:48761 +106480235 HNRNPA1P62 HGNC:HGNC:48792 +106480236 HNRNPA1P72 HGNC:HGNC:48802 +106480237 MTHFD2P2 HGNC:HGNC:48860 +106480238 KRT128P HGNC:HGNC:48882 +106480239 SLC2A13P1 HGNC:HGNC:48929 +106480240 SLC25A36P1 HGNC:HGNC:48935 +106480241 CLPTM1LP1 HGNC:HGNC:49023 +106480242 PRELID3BP5 HGNC:HGNC:49067 +106480243 PRELID3BP8 HGNC:HGNC:49070 +106480244 AZU1P1 HGNC:HGNC:49098 +106480245 RPL17P51 HGNC:HGNC:49100 +106480246 SRGNP1 HGNC:HGNC:49107 +106480247 NDE1P2 HGNC:HGNC:49116 +106480248 GRAMD4P4 HGNC:HGNC:49139 +106480249 RAP2CP1 HGNC:HGNC:49146 +106480250 ELOCP35 HGNC:HGNC:49176 +106480251 OOSP1P1 HGNC:HGNC:49240 +106480252 OOSP1P2 HGNC:HGNC:49241 +106480253 KLF2P1 HGNC:HGNC:49280 +106480254 HSPE1P6 HGNC:HGNC:49325 +106480255 HSPE1P9 HGNC:HGNC:49328 +106480256 HSPE1P13 HGNC:HGNC:49332 +106480257 HSPE1P18 HGNC:HGNC:49337 +106480258 HSPE1P21 HGNC:HGNC:49340 +106480259 HSPE1P24 HGNC:HGNC:49343 +106480260 HSPE1P25 HGNC:HGNC:49344 +106480261 HSPE1P27 HGNC:HGNC:49346 +106480262 SUMO2P12 HGNC:HGNC:49350 +106480263 SUMO2P13 HGNC:HGNC:49351 +106480264 SUMO2P14 HGNC:HGNC:49352 +106480265 COX6CP7 HGNC:HGNC:49359 +106480266 COX6CP11 HGNC:HGNC:49363 +106480267 COX6CP13 HGNC:HGNC:49365 +106480268 COX6CP15 HGNC:HGNC:49368 +106480269 COX6CP17 HGNC:HGNC:49369 +106480270 SNRPGP16 HGNC:HGNC:49373 +106480271 SNRPGP20 HGNC:HGNC:49376 +106480272 IMP3P2 HGNC:HGNC:49386 +106480273 YWHAEP3 HGNC:HGNC:49430 +106480274 IGKV1OR9-2 HGNC:HGNC:49466|IMGT/GENE-DB:IGKV1/OR9-2 +106480275 TXNP7 HGNC:HGNC:49487 +106480276 UBE2Q2P9 HGNC:HGNC:49517 +106480277 EIF1P6 HGNC:HGNC:49619 +106480278 MCRIP2P2 HGNC:HGNC:49631 +106480279 CRB3P1 HGNC:HGNC:49684 +106480280 BNIP3P9 HGNC:HGNC:49689 +106480281 BNIP3P19 HGNC:HGNC:49699 +106480282 BNIP3P31 HGNC:HGNC:49711 +106480283 BNIP3P32 HGNC:HGNC:49712 +106480284 BNIP3P35 HGNC:HGNC:49715 +106480285 BNIP3P37 HGNC:HGNC:49717 +106480286 BNIP3P11 HGNC:HGNC:49724 +106480287 LARP7P1 HGNC:HGNC:49763 +106480288 LSM1P2 HGNC:HGNC:49777 +106480289 C11orf98P1 HGNC:HGNC:49784 +106480290 SNRPCP5 HGNC:HGNC:49820 +106480291 SNRPCP16 HGNC:HGNC:49831 +106480292 SNRPCP20 HGNC:HGNC:49835 +106480293 UBTFL10 HGNC:HGNC:50287 +106480294 NENFP1 HGNC:HGNC:50298 +106480295 PDCL2P2 HGNC:HGNC:50341 +106480296 MTCO2P4 HGNC:HGNC:50349 +106480297 THEM7P HGNC:HGNC:50386 +106480298 NUTF2P3 HGNC:HGNC:50452 +106480299 CTHRC1P1 HGNC:HGNC:50463 +106480300 LLPHP2 HGNC:HGNC:50492 +106480301 TOMM20P3 HGNC:HGNC:50520 +106480302 MZT1P1 HGNC:HGNC:50605 +106480303 PRR13P2 HGNC:HGNC:50615 +106480304 MREGP1 HGNC:HGNC:50749 +106480305 AP1S2P1 HGNC:HGNC:50752 +106480306 AKIRIN1P2 HGNC:HGNC:50797 +106480307 CCND3P2 HGNC:HGNC:50852 +106480308 RNY1P10 HGNC:HGNC:50873 +106480309 RNY1P12 HGNC:HGNC:50875 +106480310 RNY1P13 HGNC:HGNC:50876 +106480311 RNY1P14 HGNC:HGNC:50877 +106480312 RNY1P16 HGNC:HGNC:50879 +106480313 RNY4P36 HGNC:HGNC:50884 +106480314 RNY4P37 HGNC:HGNC:50885 +106480315 RNY3P12 HGNC:HGNC:50888 +106480316 RNY3P14 HGNC:HGNC:50893 +106480317 MLECP1 HGNC:HGNC:51122 +106480318 MTCO1P5 HGNC:HGNC:51300 +106480319 NAMPTP3 HGNC:HGNC:51313 +106480320 TMF1P1 HGNC:HGNC:51353 +106480321 FRG2GP HGNC:HGNC:51364 +106480322 BOLA2P2 HGNC:HGNC:51438 +106480323 BOLA2P3 HGNC:HGNC:51439 +106480324 BOLA3P4 HGNC:HGNC:51443 +106480325 WBP1LP8 HGNC:HGNC:51468 +106480326 WBP1LP10 HGNC:HGNC:51470 +106480327 WBP1LP12 HGNC:HGNC:51472 +106480328 TRIM80P HGNC:HGNC:51490 +106480329 BSNDP1 HGNC:HGNC:51536 +106480330 BTG4P1 HGNC:HGNC:51544 +106480331 BUD31P1 HGNC:HGNC:51561 +106480332 BUD31P2 HGNC:HGNC:51562 +106480333 SULT1C2P2 HGNC:HGNC:51595 +106480334 BMS1P22 HGNC:HGNC:51603|Ensembl:ENSG00000232775 +106480335 ACTP1 HGNC:HGNC:51621 +106480336 RPL23AP89 HGNC:HGNC:51623 +106480337 RPL23AP91 HGNC:HGNC:51625 +106480338 RPL23AP95 HGNC:HGNC:51630 +106480339 TCF4-AS2 HGNC:HGNC:51643 +106480340 SEPT14P1 HGNC:HGNC:51685 +106480341 SEPT14P8 HGNC:HGNC:51692 +106480342 ZYXP1 HGNC:HGNC:51695 +106480343 SEPT14P12 HGNC:HGNC:51699 +106480344 SEPT14P17 HGNC:HGNC:51703 +106480345 SEPT14P24 HGNC:HGNC:51710 +106480346 GTF2IP11 HGNC:HGNC:51724 +106480347 GTF2IP22 HGNC:HGNC:51734 +106480348 NF1P10 HGNC:HGNC:51737 +106480349 DUX4L46 HGNC:HGNC:51784 +106480350 DUX4L50 HGNC:HGNC:51788 +106480351 FRG2IP HGNC:HGNC:51795 +106480352 FRG2LP HGNC:HGNC:51798 +106480353 C1QL1P1 HGNC:HGNC:51809 +106480354 DUX4L52 HGNC:HGNC:51811 +106480355 USP9YP21 HGNC:HGNC:38757 +106480356 SLC9A9-AS2 HGNC:HGNC:40929 +106480357 RNA5SP59 HGNC:HGNC:42836 +106480358 RNA5SP311 HGNC:HGNC:43211 +106480359 PTGES3P5 HGNC:HGNC:43826 +106480360 UBE2FP3 HGNC:HGNC:44537 +106480361 RNU7-96P HGNC:HGNC:45630 +106480362 RNU7-127P HGNC:HGNC:45661 +106480363 RNU7-186P HGNC:HGNC:45720 +106480364 RN7SKP25 HGNC:HGNC:45749 +106480365 RN7SKP94 HGNC:HGNC:45818 +106480366 RN7SKP140 HGNC:HGNC:45864 +106480367 RN7SKP165 HGNC:HGNC:45889 +106480368 RN7SKP234 HGNC:HGNC:45958 +106480369 RN7SKP281 HGNC:HGNC:46005 +106480370 RN7SL19P HGNC:HGNC:46035 +106480371 RN7SL110P HGNC:HGNC:46126 +106480372 RN7SL169P HGNC:HGNC:46185 +106480373 RN7SL258P HGNC:HGNC:46274 +106480374 RN7SL282P HGNC:HGNC:46298 +106480375 RN7SL335P HGNC:HGNC:46351 +106480376 RN7SL424P HGNC:HGNC:46440 +106480377 RN7SL451P HGNC:HGNC:46467 +106480378 RN7SL543P HGNC:HGNC:46559 +106480379 RN7SL624P HGNC:HGNC:46640 +106480380 RN7SL680P HGNC:HGNC:46696 +106480381 RN7SL713P HGNC:HGNC:46729 +106480382 RN7SL799P HGNC:HGNC:46815 +106480383 RN7SL854P HGNC:HGNC:46870 +106480384 RNU6ATAC25P HGNC:HGNC:46924 +106480385 RNU4-34P HGNC:HGNC:46970 +106480386 RNU4-80P HGNC:HGNC:47016 +106480387 RNU6-161P HGNC:HGNC:47124 +106480388 RNU6-232P HGNC:HGNC:47195 +106480389 RNU6-299P HGNC:HGNC:47262 +106480390 RNU6-325P HGNC:HGNC:47288 +106480391 RNU6-373P HGNC:HGNC:47336 +106480392 RNU6-441P HGNC:HGNC:47404 +106480393 RNU6-487P HGNC:HGNC:47450 +106480394 RNU6-512P HGNC:HGNC:47475 +106480395 RNU6-580P HGNC:HGNC:47543 +106480396 RNU6-628P HGNC:HGNC:47591 +106480397 RNU6-653P HGNC:HGNC:47616 +106480398 RNU6-700P HGNC:HGNC:47663 +106480399 RNU6-747P HGNC:HGNC:47710 +106480400 RNU6-794P HGNC:HGNC:47757 +106480401 RNU6-816P HGNC:HGNC:47779 +106480402 RNU6-889P HGNC:HGNC:47852 +106480403 RNU6-935P HGNC:HGNC:47898 +106480404 RNU6-956P HGNC:HGNC:47919 +106480405 RNU6-1028P HGNC:HGNC:47991 +106480406 RNU6-1075P HGNC:HGNC:48038 +106480407 RNU6-1167P HGNC:HGNC:48130 +106480408 RNU6-1188P HGNC:HGNC:48151 +106480409 RNU6-1262P HGNC:HGNC:48225 +106480410 RNU6-1309P HGNC:HGNC:48272 +106480411 RNU6-1330P HGNC:HGNC:48293 +106480412 RNU1-89P HGNC:HGNC:48431 +106480413 RNU1-150P HGNC:HGNC:48492 +106480414 RNU2-26P HGNC:HGNC:48519 +106480415 RNU2-51P HGNC:HGNC:48544 +106480416 PRR20FP HGNC:HGNC:49097 +106480417 SUMO2P15 HGNC:HGNC:49353 +106480418 BNIP3P16 HGNC:HGNC:49696 +106480419 B3GNTL1P2 HGNC:HGNC:51318 +106480420 PHBP17 HGNC:HGNC:51550 +106480421 DPY19L2P5 HGNC:HGNC:51620 +106480422 KRTAP9-10P HGNC:HGNC:34210 +106480423 RNU6-13P HGNC:HGNC:34257 +106480424 USP9YP18 HGNC:HGNC:38754 +106480425 USP9YP29 HGNC:HGNC:38765 +106480426 GPM6BP2 HGNC:HGNC:38781 +106480427 MTND6P5 HGNC:HGNC:39468 +106480428 MTND6P13 HGNC:HGNC:39476 +106480429 HLA-DQB1-AS1 HGNC:HGNC:39762|Ensembl:ENSG00000223534 +106480430 CYP2C58P HGNC:HGNC:39969 +106480431 ENO1-IT1 HGNC:HGNC:41331 +106480432 HM13-IT1 HGNC:HGNC:41424 +106480433 MTND1P35 HGNC:HGNC:42088 +106480434 TUBB4BP4 HGNC:HGNC:42333 +106480435 RNU6-61P HGNC:HGNC:42551 +106480436 RNA5SP70 HGNC:HGNC:42847 +106480437 RNA5SP149 HGNC:HGNC:43049 +106480438 RNA5SP199 HGNC:HGNC:43099 +106480439 RNA5SP312 HGNC:HGNC:43212 +106480440 LINC00500 HGNC:HGNC:43437 +106480441 GCSHP1 HGNC:HGNC:43922 +106480442 SUB1P3 HGNC:HGNC:43993 +106480443 PKMP4 HGNC:HGNC:44246 +106480444 FCF1P9 HGNC:HGNC:44621 +106480445 MED28P2 HGNC:HGNC:45079 +106480446 EIF4A2P5 HGNC:HGNC:45102 +106480447 RAB11AP2 HGNC:HGNC:45189 +106480448 RNU7-104P HGNC:HGNC:45638 +106480449 RNU7-121P HGNC:HGNC:45655 +106480450 RNU7-129P HGNC:HGNC:45663 +106480451 RNU7-147P HGNC:HGNC:45681 +106480452 RNU7-161P HGNC:HGNC:45695 +106480453 RNU7-170P HGNC:HGNC:45704 +106480454 RNU7-183P HGNC:HGNC:45717 +106480455 RNU7-197P HGNC:HGNC:45731 +106480456 RN7SKP15 HGNC:HGNC:45739 +106480457 RN7SKP29 HGNC:HGNC:45753 +106480458 RN7SKP36 HGNC:HGNC:45760 +106480459 RN7SKP50 HGNC:HGNC:45774 +106480460 RN7SKP62 HGNC:HGNC:45786 +106480461 RN7SKP69 HGNC:HGNC:45793 +106480462 RN7SKP82 HGNC:HGNC:45806 +106480463 RN7SKP97 HGNC:HGNC:45821 +106480464 RN7SKP107 HGNC:HGNC:45831 +106480465 RN7SKP113 HGNC:HGNC:45837 +106480466 RN7SKP127 HGNC:HGNC:45851 +106480467 RN7SKP148 HGNC:HGNC:45872 +106480468 RN7SKP159 HGNC:HGNC:45883 +106480469 RN7SKP172 HGNC:HGNC:45896 +106480470 RN7SKP184 HGNC:HGNC:45908 +106480471 RN7SKP191 HGNC:HGNC:45915 +106480472 RN7SKP202 HGNC:HGNC:45926 +106480473 RN7SKP214 HGNC:HGNC:45938 +106480474 RN7SKP221 HGNC:HGNC:45945 +106480475 RN7SKP233 HGNC:HGNC:45957 +106480476 RN7SKP248 HGNC:HGNC:45972 +106480477 RN7SKP261 HGNC:HGNC:45985 +106480478 RN7SKP267 HGNC:HGNC:45991 +106480479 RN7SKP279 HGNC:HGNC:46003 +106480480 RN7SKP290 HGNC:HGNC:46014 +106480481 RN7SL14P HGNC:HGNC:46030 +106480482 RN7SL23P HGNC:HGNC:46039 +106480483 RN7SL40P HGNC:HGNC:46056 +106480484 RN7SL57P HGNC:HGNC:46073 +106480485 RN7SL66P HGNC:HGNC:46082 +106480486 RN7SL96P HGNC:HGNC:46112 +106480487 RN7SL105P HGNC:HGNC:46121 +106480488 RN7SL116P HGNC:HGNC:46132 +106480489 RN7SL138P HGNC:HGNC:46154 +106480490 RN7SL153P HGNC:HGNC:46169 +106480491 RN7SL168P HGNC:HGNC:46184 +106480492 RN7SL181P HGNC:HGNC:46197 +106480493 RN7SL193P HGNC:HGNC:46209 +106480494 RN7SL209P HGNC:HGNC:46225 +106480495 RN7SL216P HGNC:HGNC:46232 +106480496 RN7SL242P HGNC:HGNC:46258 +106480497 RN7SL260P HGNC:HGNC:46276 +106480498 RN7SL280P HGNC:HGNC:46296 +106480499 RN7SL301P HGNC:HGNC:46317 +106480500 RN7SL307P HGNC:HGNC:46323 +106480501 RN7SL321P HGNC:HGNC:46337 +106480502 RN7SL334P HGNC:HGNC:46350 +106480503 RN7SL344P HGNC:HGNC:46360 +106480504 RN7SL363P HGNC:HGNC:46379 +106480505 RN7SL379P HGNC:HGNC:46395 +106480506 RN7SL392P HGNC:HGNC:46408 +106480507 RN7SL401P HGNC:HGNC:46417 +106480508 RN7SL418P HGNC:HGNC:46434 +106480509 RN7SL434P HGNC:HGNC:46450 +106480510 RN7SL443P HGNC:HGNC:46459 +106480511 RN7SL456P HGNC:HGNC:46472 +106480512 RN7SL469P HGNC:HGNC:46485 +106480513 RN7SL482P HGNC:HGNC:46498 +106480514 RN7SL491P HGNC:HGNC:46507 +106480515 RN7SL504P HGNC:HGNC:46520 +106480516 RN7SL525P HGNC:HGNC:46541 +106480517 RN7SL538P HGNC:HGNC:46554 +106480518 RN7SL553P HGNC:HGNC:46569 +106480519 RN7SL584P HGNC:HGNC:46600 +106480520 RN7SL601P HGNC:HGNC:46617 +106480521 RN7SL608P HGNC:HGNC:46624 +106480522 RN7SL623P HGNC:HGNC:46639 +106480523 RN7SL650P HGNC:HGNC:46666 +106480524 RN7SL658P HGNC:HGNC:46674 +106480525 RN7SL673P HGNC:HGNC:46689 +106480526 RN7SL697P HGNC:HGNC:46713 +106480527 RN7SL714P HGNC:HGNC:46730 +106480528 RN7SL720P HGNC:HGNC:46736 +106480529 RN7SL735P HGNC:HGNC:46751 +106480530 RN7SL757P HGNC:HGNC:46773 +106480531 RN7SL764P HGNC:HGNC:46780 +106480532 RN7SL785P HGNC:HGNC:46801 +106480533 RN7SL798P HGNC:HGNC:46814 +106480534 RN7SL813P HGNC:HGNC:46829 +106480535 RN7SL820P HGNC:HGNC:46836 +106480536 RN7SL837P HGNC:HGNC:46853 +106480537 RN7SL851P HGNC:HGNC:46867 +106480538 RN7SL863P HGNC:HGNC:46879 +106480539 RNU4ATAC7P HGNC:HGNC:46893 +106480540 RNU6ATAC10P HGNC:HGNC:46909 +106480541 RNU6ATAC20P HGNC:HGNC:46919 +106480542 RNU6ATAC26P HGNC:HGNC:46925 +106480543 RNU6ATAC36P HGNC:HGNC:46935 +106480544 RNU11-6P HGNC:HGNC:46946 +106480545 RNU4-18P HGNC:HGNC:46954 +106480546 RNU4-31P HGNC:HGNC:46967 +106480547 RNU4-56P HGNC:HGNC:46992 +106480548 RNU4-70P HGNC:HGNC:47006 +106480549 RNU4-76P HGNC:HGNC:47012 +106480550 RNU6-89P HGNC:HGNC:47052 +106480551 RNU6-97P HGNC:HGNC:47060 +106480552 RNU6-103P HGNC:HGNC:47066 +106480553 RNU6-116P HGNC:HGNC:47079 +106480554 RNU6-127P HGNC:HGNC:47090 +106480555 RNU6-141P HGNC:HGNC:47104 +106480556 RNU6-147P HGNC:HGNC:47110 +106480557 RNU6-159P HGNC:HGNC:47122 +106480558 RNU6-175P HGNC:HGNC:47138 +106480559 RNU6-181P HGNC:HGNC:47144 +106480560 RNU6-193P HGNC:HGNC:47156 +106480561 RNU6-221P HGNC:HGNC:47184 +106480562 RNU6-233P HGNC:HGNC:47196 +106480563 RNU6-239P HGNC:HGNC:47202 +106480564 RNU6-252P HGNC:HGNC:47215 +106480565 RNU6-267P HGNC:HGNC:47230 +106480566 RNU6-273P HGNC:HGNC:47236 +106480567 RNU6-286P HGNC:HGNC:47249 +106480568 RNU6-308P HGNC:HGNC:47271 +106480569 RNU6-313P HGNC:HGNC:47276 +106480570 RNU6-320P HGNC:HGNC:47283 +106480571 RNU6-333P HGNC:HGNC:47296 +106480572 RNU6-344P HGNC:HGNC:47307 +106480573 RNU6-352P HGNC:HGNC:47315 +106480574 RNU6-361P HGNC:HGNC:47324 +106480575 RNU6-375P HGNC:HGNC:47338 +106480576 RNU6-381P HGNC:HGNC:47344 +106480577 RNU6-392P HGNC:HGNC:47355 +106480578 RNU6-403P HGNC:HGNC:47366 +106480579 RNU6-416P HGNC:HGNC:47379 +106480580 RNU6-422P HGNC:HGNC:47385 +106480581 RNU6-434P HGNC:HGNC:47397 +106480582 RNU6-454P HGNC:HGNC:47417 +106480583 RNU6-480P HGNC:HGNC:47443 +106480584 RNU6-496P HGNC:HGNC:47459 +106480585 RNU6-508P HGNC:HGNC:47471 +106480586 RNU6-514P HGNC:HGNC:47477 +106480587 RNU6-527P HGNC:HGNC:47490 +106480588 RNU6-542P HGNC:HGNC:47505 +106480589 RNU6-553P HGNC:HGNC:47516 +106480590 RNU6-560P HGNC:HGNC:47523 +106480591 RNU6-573P HGNC:HGNC:47536 +106480592 RNU6-586P HGNC:HGNC:47549 +106480593 RNU6-590P HGNC:HGNC:47553 +106480594 RNU6-603P HGNC:HGNC:47566 +106480595 RNU6-615P HGNC:HGNC:47578 +106480596 RNU6-627P HGNC:HGNC:47590 +106480597 RNU6-636P HGNC:HGNC:47599 +106480598 RNU6-647P HGNC:HGNC:47610 +106480599 RNU6-660P HGNC:HGNC:47623 +106480600 RNU6-666P HGNC:HGNC:47629 +106480601 RNU6-680P HGNC:HGNC:47643 +106480602 RNU6-708P HGNC:HGNC:47671 +106480603 RNU6-714P HGNC:HGNC:47677 +106480604 RNU6-726P HGNC:HGNC:47689 +106480605 RNU6-743P HGNC:HGNC:47706 +106480606 RNU6-749P HGNC:HGNC:47712 +106480607 RNU6-761P HGNC:HGNC:47724 +106480608 RNU6-776P HGNC:HGNC:47739 +106480609 RNU6-788P HGNC:HGNC:47751 +106480610 RNU6-795P HGNC:HGNC:47758 +106480611 RNU6-815P HGNC:HGNC:47778 +106480612 RNU6-824P HGNC:HGNC:47787 +106480613 RNU6-830P HGNC:HGNC:47793 +106480614 RNU6-843P HGNC:HGNC:47806 +106480615 RNU6-857P HGNC:HGNC:47820 +106480616 RNU6-869P HGNC:HGNC:47832 +106480617 RNU6-877P HGNC:HGNC:47840 +106480618 RNU6-890P HGNC:HGNC:47853 +106480619 RNU6-902P HGNC:HGNC:47865 +106480620 RNU6-907P HGNC:HGNC:47870 +106480621 RNU6-924P HGNC:HGNC:47887 +106480622 RNU6-930P HGNC:HGNC:47893 +106480623 RNU6-943P HGNC:HGNC:47906 +106480624 RNU6-955P HGNC:HGNC:47918 +106480625 RNU6-966P HGNC:HGNC:47929 +106480626 RNU6-977P HGNC:HGNC:47940 +106480627 RNU6-990P HGNC:HGNC:47953 +106480628 RNU6-1001P HGNC:HGNC:47964 +106480629 RNU6-1007P HGNC:HGNC:47970 +106480630 RNU6-1016P HGNC:HGNC:47979 +106480631 RNU6-1026P HGNC:HGNC:47989 +106480632 RNU6-1034P HGNC:HGNC:47997 +106480633 RNU6-1044P HGNC:HGNC:48007 +106480634 RNU6-1062P HGNC:HGNC:48025 +106480635 RNU6-1074P HGNC:HGNC:48037 +106480636 RNU6-1081P HGNC:HGNC:48044 +106480637 RNU6-1091P HGNC:HGNC:48054 +106480638 RNU6-1110P HGNC:HGNC:48073 +106480639 RNU6-1115P HGNC:HGNC:48078 +106480640 RNU6-1127P HGNC:HGNC:48090 +106480641 RNU6-1138P HGNC:HGNC:48101 +106480642 RNU6-1148P HGNC:HGNC:48111 +106480643 RNU6-1153P HGNC:HGNC:48116 +106480644 RNU6-1164P HGNC:HGNC:48127 +106480645 RNU6-1177P HGNC:HGNC:48140 +106480646 RNU6-1189P HGNC:HGNC:48152 +106480647 RNU6-1195P HGNC:HGNC:48158 +106480648 RNU6-1207P HGNC:HGNC:48170 +106480649 RNU6-1219P HGNC:HGNC:48182 +106480650 RNU6-1225P HGNC:HGNC:48188 +106480651 RNU6-1237P HGNC:HGNC:48200 +106480652 RNU6-1249P HGNC:HGNC:48212 +106480653 RNU6-1263P HGNC:HGNC:48226 +106480654 RNU6-1268P HGNC:HGNC:48231 +106480655 RNU6-1279P HGNC:HGNC:48242 +106480656 RNU6-1292P HGNC:HGNC:48255 +106480657 RNU6-1297P HGNC:HGNC:48260 +106480658 RNU6-1310P HGNC:HGNC:48273 +106480659 RNU6-1320P HGNC:HGNC:48283 +106480660 RNU6-1332P HGNC:HGNC:48295 +106480661 RNU6-1336P HGNC:HGNC:48299 +106480662 RNU1-30P HGNC:HGNC:48372 +106480663 RNU1-46P HGNC:HGNC:48388 +106480664 RNU1-63P HGNC:HGNC:48405 +106480665 RNU1-78P HGNC:HGNC:48420 +106480666 RNU1-86P HGNC:HGNC:48428 +106480667 RNU1-101P HGNC:HGNC:48443 +106480668 RNU1-119P HGNC:HGNC:48461 +106480669 RNU1-140P HGNC:HGNC:48482 +106480670 RNU2-28P HGNC:HGNC:48521 +106480671 RNU2-40P HGNC:HGNC:48533 +106480672 RNU2-47P HGNC:HGNC:48540 +106480673 RNU2-61P HGNC:HGNC:48554 +106480674 ENPP7P5 HGNC:HGNC:48688 +106480675 HNRNPA1P76 HGNC:HGNC:48806 +106480676 KRT8P51 HGNC:HGNC:48883 +106480677 SQSTM1P1 HGNC:HGNC:49099 +106480678 KLF2P2 HGNC:HGNC:49281 +106480679 SUMO2P16 HGNC:HGNC:49354 +106480680 SNRPGP18 HGNC:HGNC:49374 +106480681 DYNLL1P5 HGNC:HGNC:49656 +106480682 GTF3AP2 HGNC:HGNC:49745 +106480683 AARSP1 HGNC:HGNC:49894 +106480684 MTCO1P4 HGNC:HGNC:50350 +106480685 LLPHP1 HGNC:HGNC:50491 +106480686 RNY3P16 HGNC:HGNC:50891 +106480687 C8orf59P2 HGNC:HGNC:51357 +106480688 BRWD1P3 HGNC:HGNC:51530 +106480689 SAP18P1 HGNC:HGNC:51567 +106480690 RPL23AP90 HGNC:HGNC:51624 +106480691 DNAJC19P4 HGNC:HGNC:45067 +106480692 RN7SKP186 HGNC:HGNC:45910 +106480693 RN7SL199P HGNC:HGNC:46215 +106480694 RN7SL369P HGNC:HGNC:46385 +106480695 RN7SL738P HGNC:HGNC:46754 +106480696 RNU4ATAC17P HGNC:HGNC:46903 +106480697 RNU6-253P HGNC:HGNC:47216 +106480698 RNU6-394P HGNC:HGNC:47357 +106480699 RNU6-841P HGNC:HGNC:47804 +106480700 RNU6-1096P HGNC:HGNC:48059 +106480701 RNU6-1235P HGNC:HGNC:48198 +106480702 RNU2-72P HGNC:HGNC:48565 +106480703 RNU6-40P HGNC:HGNC:34248 +106480704 RNU6-25P HGNC:HGNC:34251 +106480705 RNU6-17P HGNC:HGNC:34261 +106480706 RNU6-20P HGNC:HGNC:34264 +106480707 RNU6-24P HGNC:HGNC:34268 +106480708 RNU6-32P HGNC:HGNC:34276 +106480709 RNU6-38P HGNC:HGNC:34282 +106480710 RNU6-47P HGNC:HGNC:34291 +106480711 ZNF736P5Y HGNC:HGNC:38597 +106480712 FABP5P13 HGNC:HGNC:38717 +106480713 USP9YP15 HGNC:HGNC:38751 +106480714 USP9YP17 HGNC:HGNC:38753 +106480715 USP9YP25 HGNC:HGNC:38761 +106480716 USP9YP27 HGNC:HGNC:38763 +106480717 USP9YP20 HGNC:HGNC:38767 +106480718 USP9YP32 HGNC:HGNC:38776 +106480719 USP9YP35 HGNC:HGNC:38779 +106480720 GPM6BP1 HGNC:HGNC:38782 +106480721 PRYP6 HGNC:HGNC:38786 +106480722 HSFY6P HGNC:HGNC:38790 +106480723 HSFY8P HGNC:HGNC:38792 +106480724 MLLT10P2 HGNC:HGNC:39141 +106480725 HMGN1P12 HGNC:HGNC:39356 +106480726 MTND6P8 HGNC:HGNC:39471 +106480727 MTND6P11 HGNC:HGNC:39474 +106480728 MTND6P17 HGNC:HGNC:39480 +106480729 RPL7L1P10 HGNC:HGNC:39492 +106480730 C4B-AS1 HGNC:HGNC:39752 +106480731 C6orf47-AS1 HGNC:HGNC:39767 +106480732 PSMC1P5 HGNC:HGNC:39780 +106480733 CYP4F44P HGNC:HGNC:39957 +106480734 CYP2C61P HGNC:HGNC:39972 +106480735 XIAP-AS1 HGNC:HGNC:40078 +106480736 MCCC1-AS1 HGNC:HGNC:40366 +106480737 ITCH-AS1 HGNC:HGNC:40659 +106480738 OSTN-AS1 HGNC:HGNC:41250|Ensembl:ENSG00000233308 +106480739 RHOA-IT1 HGNC:HGNC:41308 +106480740 GK-IT1 HGNC:HGNC:41339 +106480741 ZNF346-IT1 HGNC:HGNC:41423 +106480742 RABGAP1L-IT1 HGNC:HGNC:41471 +106480743 BRWD1-IT1 HGNC:HGNC:41920 +106480744 MTND1P12 HGNC:HGNC:42061 +106480745 TUBBP11 HGNC:HGNC:42184 +106480746 TUBB4BP3 HGNC:HGNC:42331 +106480747 TUBB4BP5 HGNC:HGNC:42335 +106480748 CYP2C60P HGNC:HGNC:42410 +106480749 CYP3A54P HGNC:HGNC:42413 +106480750 RNU6-60P HGNC:HGNC:42550 +106480751 RNU6-65P HGNC:HGNC:42555 +106480752 RNU6-74P HGNC:HGNC:42564 +106480753 RNU4ATAC3P HGNC:HGNC:42575 +106480754 RNA5SP57 HGNC:HGNC:42834 +106480755 RNA5SP100 HGNC:HGNC:42898 +106480756 RNA5SP134 HGNC:HGNC:43034 +106480757 RNA5SP161 HGNC:HGNC:43061 +106480758 RNA5SP175 HGNC:HGNC:43075 +106480759 RNA5SP221 HGNC:HGNC:43121 +106480760 RNA5SP253 HGNC:HGNC:43153 +106480761 RNA5SP298 HGNC:HGNC:43198 +106480762 RNA5SP310 HGNC:HGNC:43210 +106480763 RNA5SP333 HGNC:HGNC:43233 +106480764 RNA5SP351 HGNC:HGNC:43251 +106480765 RNA5SP370 HGNC:HGNC:43270 +106480766 RNA5SP389 HGNC:HGNC:43289 +106480767 RNA5SP429 HGNC:HGNC:43329 +106480768 RNA5SP442 HGNC:HGNC:43342 +106480769 RNA5SP468 HGNC:HGNC:43368 +106480770 RNA5SP498 HGNC:HGNC:43398 +106480771 RNA5SP520 HGNC:HGNC:43420 +106480772 RNA5SP523 HGNC:HGNC:43423 +106480773 TBC1D3P7 HGNC:HGNC:43569 +106480774 PRSS3P4 HGNC:HGNC:43789 +106480775 PTGES3P4 HGNC:HGNC:43825 +106480776 SLC25A18P1 HGNC:HGNC:43857 +106480777 FAM96AP1 HGNC:HGNC:43861 +106480778 ARL5AP3 HGNC:HGNC:43935 +106480779 WBP1LP4 HGNC:HGNC:43951 +106480780 WBP1LP5 HGNC:HGNC:43957 +106480781 TSEN15P2 HGNC:HGNC:43963 +106480782 POLHP1 HGNC:HGNC:43967 +106480783 CIR1P3 HGNC:HGNC:44013 +106480784 TRMT112P5 HGNC:HGNC:44024 +106480785 NDUFS5P6 HGNC:HGNC:44044 +106480786 ATG4AP1 HGNC:HGNC:44081 +106480787 VWA8P1 HGNC:HGNC:44271 +106480788 CST9LP2 HGNC:HGNC:44337 +106480789 ALG1L11P HGNC:HGNC:44380 +106480790 ROBO2P1 HGNC:HGNC:44386 +106480791 HMGN2P47 HGNC:HGNC:44422 +106480792 CHCHD4P3 HGNC:HGNC:44491 +106480793 CRIP1P1 HGNC:HGNC:44516 +106480794 MRPL42P6 HGNC:HGNC:44533 +106480795 MTATP8P1 HGNC:HGNC:44571 +106480796 MTATP6P1 HGNC:HGNC:44575 +106480797 MTATP6P4 HGNC:HGNC:44578 +106480798 MTATP6P7 HGNC:HGNC:44581 +106480799 FCF1P4 HGNC:HGNC:44616 +106480800 UBL5P4 HGNC:HGNC:44642 +106480801 SDCBP2P1 HGNC:HGNC:44685 +106480802 UBE2V2P4 HGNC:HGNC:44892 +106480803 HSPA8P13 HGNC:HGNC:44928 +106480804 TPRKBP2 HGNC:HGNC:44944 +106480805 NIFKP9 HGNC:HGNC:44957 +106480806 NDUFA3P4 HGNC:HGNC:45053 +106480807 KRT19P6 HGNC:HGNC:45076 +106480808 MED28P6 HGNC:HGNC:45083 +106480809 CACYBPP3 HGNC:HGNC:45124 +106480810 RFPL4AP3 HGNC:HGNC:45139 +106480811 PIGPP4 HGNC:HGNC:45156 +106480812 PIGQP1 HGNC:HGNC:45157 +106480813 RNU7-93P HGNC:HGNC:45627 +106480814 RNU7-99P HGNC:HGNC:45633 +106480815 RNU7-110P HGNC:HGNC:45644 +106480816 RNU7-116P HGNC:HGNC:45650 +106480817 RNU7-120P HGNC:HGNC:45654 +106480818 RNU7-125P HGNC:HGNC:45659 +106480819 RNU7-128P HGNC:HGNC:45662 +106480820 RNU7-134P HGNC:HGNC:45668 +106480821 RNU7-137P HGNC:HGNC:45671 +106480822 RNU7-141P HGNC:HGNC:45675 +106480823 RNU7-148P HGNC:HGNC:45682 +106480824 RNU7-151P HGNC:HGNC:45685 +106480825 RNU7-155P HGNC:HGNC:45689 +106480826 RNU7-157P HGNC:HGNC:45691 +106480827 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RNU6-1117P HGNC:HGNC:48080 +106481533 RNU6-1119P HGNC:HGNC:48082 +106481534 RNU6-1124P HGNC:HGNC:48087 +106481535 RNU6-1126P HGNC:HGNC:48089 +106481536 RNU6-1129P HGNC:HGNC:48092 +106481537 RNU6-1133P HGNC:HGNC:48096 +106481538 RNU6-1135P HGNC:HGNC:48098 +106481539 RNU6-1139P HGNC:HGNC:48102 +106481540 RNU6-1141P HGNC:HGNC:48104 +106481541 RNU6-1145P HGNC:HGNC:48108 +106481542 RNU6-1149P HGNC:HGNC:48112 +106481543 RNU6-1151P HGNC:HGNC:48114 +106481544 RNU6-1155P HGNC:HGNC:48118 +106481545 RNU6-1157P HGNC:HGNC:48120 +106481546 RNU6-1160P HGNC:HGNC:48123 +106481547 RNU6-1163P HGNC:HGNC:48126 +106481548 RNU6-1168P HGNC:HGNC:48131 +106481549 RNU6-1172P HGNC:HGNC:48135 +106481550 RNU6-1174P HGNC:HGNC:48137 +106481551 RNU6-1176P HGNC:HGNC:48139 +106481552 RNU6-1180P HGNC:HGNC:48143 +106481553 RNU6-1184P HGNC:HGNC:48147 +106481554 RNU6-1187P HGNC:HGNC:48150 +106481555 RNU6-1191P HGNC:HGNC:48154 +106481556 RNU6-1193P HGNC:HGNC:48156 +106481557 RNU6-1194P HGNC:HGNC:48157 +106481558 RNU6-1197P HGNC:HGNC:48160 +106481559 RNU6-1200P HGNC:HGNC:48163 +106481560 RNU6-1204P HGNC:HGNC:48167 +106481561 RNU6-1206P HGNC:HGNC:48169 +106481562 RNU6-1210P HGNC:HGNC:48173 +106481563 RNU6-1213P HGNC:HGNC:48176 +106481564 RNU6-1217P HGNC:HGNC:48180 +106481565 RNU6-1220P HGNC:HGNC:48183 +106481566 RNU6-1223P HGNC:HGNC:48186 +106481567 RNU6-1227P HGNC:HGNC:48190 +106481568 RNU6-1229P HGNC:HGNC:48192 +106481569 RNU6-1233P HGNC:HGNC:48196 +106481570 RNU6-1236P HGNC:HGNC:48199 +106481571 RNU6-1239P HGNC:HGNC:48202 +106481572 RNU6-1241P HGNC:HGNC:48204 +106481573 RNU6-1243P HGNC:HGNC:48206 +106481574 RNU6-1247P HGNC:HGNC:48210 +106481575 RNU6-1250P HGNC:HGNC:48213 +106481576 RNU6-1254P HGNC:HGNC:48217 +106481577 RNU6-1257P HGNC:HGNC:48220 +106481578 RNU6-1260P HGNC:HGNC:48223 +106481579 RNU6-1265P HGNC:HGNC:48228 +106481580 RNU6-1267P HGNC:HGNC:48230 +106481581 RNU6-1270P HGNC:HGNC:48233 +106481582 RNU6-1274P HGNC:HGNC:48237 +106481583 RNU6-1276P HGNC:HGNC:48239 +106481584 RNU6-1280P HGNC:HGNC:48243 +106481585 RNU6-1282P HGNC:HGNC:48245 +106481586 RNU6-1286P HGNC:HGNC:48249 +106481587 RNU6-1289P HGNC:HGNC:48252 +106481588 RNU6-1291P HGNC:HGNC:48254 +106481589 RNU6-318P HGNC:HGNC:47281 +106481590 RNU6-1298P HGNC:HGNC:48261 +106481591 RNU6-1301P HGNC:HGNC:48264 +106481592 RNU6-1305P HGNC:HGNC:48268 +106481593 RNU6-1307P HGNC:HGNC:48270 +106481594 RNU6-1312P HGNC:HGNC:48275 +106481595 RNU6-1314P HGNC:HGNC:48277 +106481596 RNU6-1317P HGNC:HGNC:48280 +106481597 RNU6-1321P HGNC:HGNC:48284 +106481598 RNU6-1323P HGNC:HGNC:48286 +106481599 RNU6-1327P HGNC:HGNC:48290 +106481600 RNU6-1329P HGNC:HGNC:48292 +106481601 RNU6-1333P HGNC:HGNC:48296 +106481602 RNU6-1337P HGNC:HGNC:48300 +106481603 RNU6-1339P HGNC:HGNC:48302 +106481604 RNU1-8P HGNC:HGNC:48307 +106481605 TCP11X3P HGNC:HGNC:48370 +106481606 RNU1-31P HGNC:HGNC:48373 +106481607 RNU1-34P HGNC:HGNC:48376 +106481608 RNU1-38P HGNC:HGNC:48380 +106481609 RNU1-42P HGNC:HGNC:48384 +106481610 RNU1-45P HGNC:HGNC:48387 +106481611 RNU1-54P HGNC:HGNC:48396 +106481612 RNU1-58P HGNC:HGNC:48400 +106481613 RNU1-62P HGNC:HGNC:48404 +106481614 RNU1-65P HGNC:HGNC:48407 +106481615 RNU1-68P HGNC:HGNC:48410 +106481616 RNU1-73P HGNC:HGNC:48415 +106481617 RNU1-76P HGNC:HGNC:48418 +106481618 RNU1-84P HGNC:HGNC:48426 +106481619 RNU1-88P HGNC:HGNC:48430 +106481620 RNU1-92P HGNC:HGNC:48434 +106481621 RNU1-95P HGNC:HGNC:48437 +106481622 RNU1-98P HGNC:HGNC:48440 +106481623 RNU1-103P HGNC:HGNC:48445 +106481624 RNU1-106P HGNC:HGNC:48448 +106481625 RNU1-109P HGNC:HGNC:48451 +106481626 RNU1-114P HGNC:HGNC:48456 +106481627 RNU1-120P HGNC:HGNC:48462 +106481628 RNU1-123P HGNC:HGNC:48465 +106481629 RNU1-124P HGNC:HGNC:48466 +106481630 RNU1-129P HGNC:HGNC:48471 +106481631 RNU1-133P HGNC:HGNC:48475 +106481632 RNU1-136P HGNC:HGNC:48478 +106481633 RNU1-141P HGNC:HGNC:48483 +106481634 RNU1-143P HGNC:HGNC:48485 +106481635 RNU1-148P HGNC:HGNC:48490 +106481636 RNU2-9P HGNC:HGNC:48502 +106481637 RNU2-11P HGNC:HGNC:48504 +106481638 RNU2-14P HGNC:HGNC:48507 +106481639 RNU2-16P HGNC:HGNC:48509 +106481640 RNU2-20P HGNC:HGNC:48513 +106481641 RNU2-23P HGNC:HGNC:48516 +106481642 RNU2-27P HGNC:HGNC:48520 +106481643 RNU2-30P HGNC:HGNC:48523 +106481644 RNU2-32P HGNC:HGNC:48525 +106481645 RNU2-36P HGNC:HGNC:48529 +106481646 RNU2-38P HGNC:HGNC:48531 +106481647 RNU2-42P HGNC:HGNC:48535 +106481648 RNU2-44P HGNC:HGNC:48537 +106481649 RNU2-48P HGNC:HGNC:48541 +106481650 RNU2-50P HGNC:HGNC:48543 +106481651 RNU2-54P HGNC:HGNC:48547 +106481652 RNU2-58P HGNC:HGNC:48551 +106481653 RNU2-60P HGNC:HGNC:48553 +106481654 RNU2-64P HGNC:HGNC:48557 +106481655 RNU2-66P HGNC:HGNC:48559 +106481656 RNU2-69P HGNC:HGNC:48562 +106481657 MED15P3 HGNC:HGNC:48652 +106481658 ENPP7P3 HGNC:HGNC:48686 +106481659 RARRES2P3 HGNC:HGNC:48702 +106481660 RARRES2P7 HGNC:HGNC:48709 +106481661 HNRNPDP2 HGNC:HGNC:48749 +106481662 HNRNPDLP3 HGNC:HGNC:48754 +106481663 HNRNPA1P49 HGNC:HGNC:48779 +106481664 HNRNPA1P65 HGNC:HGNC:48795 +106481665 MTHFD2P3 HGNC:HGNC:48866 +106481666 RPL37P25 HGNC:HGNC:49020 +106481667 PRELID3BP2 HGNC:HGNC:49064 +106481668 MEMO1P5 HGNC:HGNC:49102 +106481669 KLF17P2 HGNC:HGNC:49135 +106481670 ELOCP30 HGNC:HGNC:49171 +106481671 ELOCP34 HGNC:HGNC:49175 +106481672 KLF2P3 HGNC:HGNC:49282 +106481673 HSPE1P11 HGNC:HGNC:49330 +106481674 HSPE1P14 HGNC:HGNC:49333 +106481675 HSPE1P19 HGNC:HGNC:49338 +106481676 HSPE1P23 HGNC:HGNC:49342 +106481677 HSPE1P26 HGNC:HGNC:49345 +106481678 SUMO2P10 HGNC:HGNC:49348 +106481679 SUMO2P18 HGNC:HGNC:49356 +106481680 COX6CP8 HGNC:HGNC:49360 +106481681 COX6CP10 HGNC:HGNC:49362 +106481682 COX6CP12 HGNC:HGNC:49364 +106481683 COX6CP14 HGNC:HGNC:49366 +106481684 COX6CP18 HGNC:HGNC:49370 +106481685 SNRPGP17 HGNC:HGNC:49372 +106481686 SNRPGP19 HGNC:HGNC:49375 +106481687 PDIA3P2 HGNC:HGNC:49403 +106481688 YWHAEP2 HGNC:HGNC:49429 +106481689 IGKV1OR2-2 HGNC:HGNC:49465|IMGT/GENE-DB:IGKV1/OR2-2 +106481690 EIF1P5 HGNC:HGNC:49618 +106481691 EIF1P7 HGNC:HGNC:49620 +106481692 BNIP3P15 HGNC:HGNC:49695 +106481693 BNIP3P18 HGNC:HGNC:49698 +106481694 BNIP3P30 HGNC:HGNC:49710 +106481695 BNIP3P33 HGNC:HGNC:49713 +106481696 BNIP3P36 HGNC:HGNC:49716 +106481697 BNIP3P42 HGNC:HGNC:49722 +106481698 ECM1P2 HGNC:HGNC:49737 +106481699 LARP7P2 HGNC:HGNC:49764 +106481700 LARP7P3 HGNC:HGNC:49765 +106481701 SNRPCP10 HGNC:HGNC:49825 +106481702 SNRPCP17 HGNC:HGNC:49832 +106481703 NENFP3 HGNC:HGNC:50300 +106481704 PAXBP1P1 HGNC:HGNC:50352 +106481706 NUTF2P5 HGNC:HGNC:50454 +106481707 CARSP2 HGNC:HGNC:50478 +106481708 VTA1P1 HGNC:HGNC:50483 +106481709 DDX43P3 HGNC:HGNC:50782 +106481710 RNY1P11 HGNC:HGNC:50874 +106481711 RNY1P15 HGNC:HGNC:50878 +106481712 RNY4P34 HGNC:HGNC:50882 +106481713 RNY3P11 HGNC:HGNC:50887 +106481714 RNY3P13 HGNC:HGNC:50889 +106481715 IMMP1LP3 HGNC:HGNC:51134 +106481716 SMARCE1P7 HGNC:HGNC:51208 +106481717 B4GALNT2P1 HGNC:HGNC:51319 +106481718 CFTRP3 HGNC:HGNC:51352 +106481719 C8orf59P1 HGNC:HGNC:51355 +106481720 ENPP7P14 HGNC:HGNC:51387 +106481721 BRD9P1 HGNC:HGNC:51445 +106481722 GPAA1P2 HGNC:HGNC:51484 +106481723 ART2BP HGNC:HGNC:51489 +106481724 BRWD1P1 HGNC:HGNC:51528 +106481725 BSNDP3 HGNC:HGNC:51538 +106481726 BSNDP4 HGNC:HGNC:51539 +106481727 SETD6P1 HGNC:HGNC:51596 +106481728 DUX4L28 HGNC:HGNC:51605 +106481729 C1DP5 HGNC:HGNC:51613 +106481730 C1GALT1P3 HGNC:HGNC:51616 +106481731 RPL23AP92 HGNC:HGNC:51627 +106481732 CAB39P1 HGNC:HGNC:51641 +106481733 SEPT14P13 HGNC:HGNC:51700 +106481734 GTF2IP9 HGNC:HGNC:51721 +106481735 GTF2IP14 HGNC:HGNC:51726 +106481736 NF1P11 HGNC:HGNC:51738 +106481737 AGGF1P6 HGNC:HGNC:51744 +106481738 DUX4L47 HGNC:HGNC:51785 +106481739 FRG2MP HGNC:HGNC:51799 +106481740 DUX4L51 HGNC:HGNC:51810 +106481741 DUXAP11 HGNC:HGNC:51812 +106481742 FRGCA HGNC:HGNC:51844|Ensembl:ENSG00000236663 +106481743 MTND6P12 HGNC:HGNC:39475 +106481744 AGBL5-IT1 HGNC:HGNC:41484 +106481745 RNA5SP443 HGNC:HGNC:43343 +106481746 UBE2V1P7 HGNC:HGNC:44890 +106481747 RNU7-159P HGNC:HGNC:45693 +106481748 RN7SKP72 HGNC:HGNC:45796 +106481749 RN7SKP119 HGNC:HGNC:45843 +106481750 RN7SKP212 HGNC:HGNC:45936 +106481751 RN7SKP259 HGNC:HGNC:45983 +106481752 RN7SL78P HGNC:HGNC:46094 +106481753 RN7SL145P HGNC:HGNC:46161 +106481754 RN7SL223P HGNC:HGNC:46239 +106481755 RN7SL311P HGNC:HGNC:46327 +106481756 RN7SL393P HGNC:HGNC:46409 +106481757 RN7SL480P HGNC:HGNC:46496 +106481758 RN7SL505P HGNC:HGNC:46521 +106481759 RN7SL598P HGNC:HGNC:46614 +106481760 RN7SL656P HGNC:HGNC:46672 +106481761 RN7SL774P HGNC:HGNC:46790 +106481762 RN7SL827P HGNC:HGNC:46843 +106481763 RNU4-13P HGNC:HGNC:46949 +106481764 RNU4-59P HGNC:HGNC:46995 +106481765 RNU6-114P HGNC:HGNC:47077 +106481766 RNU6-207P HGNC:HGNC:47170 +106481767 RNU6-278P HGNC:HGNC:47241 +106481768 RNU6-346P HGNC:HGNC:47309 +106481769 RNU6-420P HGNC:HGNC:47383 +106481770 RNU6-466P HGNC:HGNC:47429 +106481771 RNU6-559P HGNC:HGNC:47522 +106481772 RNU6-607P HGNC:HGNC:47570 +106481773 RNU6-674P HGNC:HGNC:47637 +106481774 RNU6-721P HGNC:HGNC:47684 +106481775 RNU6-768P HGNC:HGNC:47731 +106481776 RNU6-864P HGNC:HGNC:47827 +106481777 RNU6-910P HGNC:HGNC:47873 +106481778 RNU6-1003P HGNC:HGNC:47966 +106481779 RNU6-1049P HGNC:HGNC:48012 +106481780 RNU6-1121P HGNC:HGNC:48084 +106481781 RNU6-1214P HGNC:HGNC:48177 +106481782 RNU6-1283P HGNC:HGNC:48246 +106481783 RNU1-36P HGNC:HGNC:48378 +106481784 NDUFA5P7 HGNC:HGNC:48849 +106481785 YWHAEP4 HGNC:HGNC:49440 +106481786 SNRPCP13 HGNC:HGNC:49828 +106481787 FTH1P6 HGNC:HGNC:39088 +106481788 MTND6P19 HGNC:HGNC:39482 +106481789 TRMT2B-AS1 HGNC:HGNC:41116 +106481790 RC3H1-IT1 HGNC:HGNC:41496 +106481791 CYP4A44P HGNC:HGNC:42416 +106481792 RNU6-77P HGNC:HGNC:42567 +106481793 RNA5SP254 HGNC:HGNC:43154 +106481794 RNA5SP350 HGNC:HGNC:43250 +106481795 HMBOX1-IT1 HGNC:HGNC:43632 +106481796 LRRC37A15P HGNC:HGNC:43819 +106481797 WBP1LP6 HGNC:HGNC:43956 +106481798 RPEP5 HGNC:HGNC:44524 +106481799 RNU7-94P HGNC:HGNC:45628 +106481800 RNU7-111P HGNC:HGNC:45645 +106481801 RNU7-138P HGNC:HGNC:45672 +106481802 RNU7-154P HGNC:HGNC:45688 +106481803 RNU7-176P HGNC:HGNC:45710 +106481804 RNU7-193P HGNC:HGNC:45727 +106481805 RN7SKP22 HGNC:HGNC:45746 +106481806 RN7SKP43 HGNC:HGNC:45767 +106481807 RN7SKP56 HGNC:HGNC:45780 +106481808 RN7SKP76 HGNC:HGNC:45800 +106481809 RN7SKP90 HGNC:HGNC:45814 +106481810 RN7SKP102 HGNC:HGNC:45826 +106481811 RN7SKP121 HGNC:HGNC:45845 +106481812 RN7SKP133 HGNC:HGNC:45857 +106481813 RN7SKP153 HGNC:HGNC:45877 +106481814 RN7SKP166 HGNC:HGNC:45890 +106481815 RN7SKP179 HGNC:HGNC:45903 +106481816 RN7SKP195 HGNC:HGNC:45919 +106481817 RN7SKP208 HGNC:HGNC:45932 +106481818 RN7SKP227 HGNC:HGNC:45951 +106481819 RN7SKP243 HGNC:HGNC:45967 +106481820 RN7SKP254 HGNC:HGNC:45978 +106481821 RN7SKP273 HGNC:HGNC:45997 +106481822 RN7SKP286 HGNC:HGNC:46010 +106481823 RN7SKP296 HGNC:HGNC:46020 +106481824 RN7SL34P HGNC:HGNC:46050 +106481825 RN7SL48P HGNC:HGNC:46064 +106481826 RN7SL128P HGNC:HGNC:46144 +106481827 RN7SL146P HGNC:HGNC:46162 +106481828 RN7SL162P HGNC:HGNC:46178 +106481829 RN7SL187P HGNC:HGNC:46203 +106481830 RN7SL201P HGNC:HGNC:46217 +106481831 RN7SL222P HGNC:HGNC:46238 +106481832 RN7SL252P HGNC:HGNC:46268 +106481833 RN7SL267P HGNC:HGNC:46283 +106481834 RN7SL273P HGNC:HGNC:46289 +106481835 RN7SL293P HGNC:HGNC:46309 +106481836 RN7SL314P HGNC:HGNC:46330 +106481837 RN7SL328P HGNC:HGNC:46344 +106481838 RN7SL354P HGNC:HGNC:46370 +106481839 RN7SL371P HGNC:HGNC:46387 +106481840 RN7SL385P HGNC:HGNC:46401 +106481841 RN7SL408P HGNC:HGNC:46424 +106481842 RN7SL426P HGNC:HGNC:46442 +106481843 RN7SL448P HGNC:HGNC:46464 +106481844 RN7SL461P HGNC:HGNC:46477 +106481845 RN7SL475P HGNC:HGNC:46491 +106481846 RN7SL497P HGNC:HGNC:46513 +106481847 RN7SL518P HGNC:HGNC:46534 +106481848 RN7SL545P HGNC:HGNC:46561 +106481849 RN7SL559P HGNC:HGNC:46575 +106481850 RN7SL566P HGNC:HGNC:46582 +106481851 RN7SL592P HGNC:HGNC:46608 +106481852 RN7SL617P HGNC:HGNC:46633 +106481853 RN7SL644P HGNC:HGNC:46660 +106481854 RN7SL666P HGNC:HGNC:46682 +106481855 RN7SL679P HGNC:HGNC:46695 +106481856 RN7SL705P HGNC:HGNC:46721 +106481857 RN7SL728P HGNC:HGNC:46744 +106481858 RN7SL745P HGNC:HGNC:46761 +106481859 RN7SL775P HGNC:HGNC:46791 +106481860 RN7SL791P HGNC:HGNC:46807 +106481861 RN7SL808P HGNC:HGNC:46824 +106481862 RN7SL831P HGNC:HGNC:46847 +106481863 RN7SL845P HGNC:HGNC:46861 +106481864 RN7SL869P HGNC:HGNC:46885 +106481865 RNU4ATAC12P HGNC:HGNC:46898 +106481866 RNU4ATAC18P HGNC:HGNC:46904 +106481867 RNU6ATAC15P HGNC:HGNC:46914 +106481868 RNU6ATAC30P HGNC:HGNC:46929 +106481869 RNU6ATAC41P HGNC:HGNC:46940 +106481870 RNU4-25P HGNC:HGNC:46961 +106481871 RNU4-50P HGNC:HGNC:46986 +106481872 RNU4-64P HGNC:HGNC:47000 +106481873 RNU4-84P HGNC:HGNC:47020 +106481874 RMRPP5 HGNC:HGNC:47035 +106481875 RNU6-108P HGNC:HGNC:47071 +106481876 RNU6-122P HGNC:HGNC:47085 +106481877 RNU6-133P HGNC:HGNC:47096 +106481878 RNU6-154P HGNC:HGNC:47117 +106481879 RNU6-166P HGNC:HGNC:47129 +106481880 RNU6-187P HGNC:HGNC:47150 +106481881 RNU6-199P HGNC:HGNC:47162 +106481882 RNU6-206P HGNC:HGNC:47169 +106481883 RNU6-227P HGNC:HGNC:47190 +106481884 RNU6-246P HGNC:HGNC:47209 +106481885 RNU6-261P HGNC:HGNC:47224 +106481886 RNU6-280P HGNC:HGNC:47243 +106481887 RNU6-327P HGNC:HGNC:47290 +106481888 RNU6-339P HGNC:HGNC:47302 +106481889 RNU6-355P HGNC:HGNC:47318 +106481890 RNU6-367P HGNC:HGNC:47330 +106481891 RNU6-387P HGNC:HGNC:47350 +106481892 RNU6-399P HGNC:HGNC:47362 +106481893 RNU6-410P HGNC:HGNC:47373 +106481894 RNU6-428P HGNC:HGNC:47391 +106481895 RNU6-440P HGNC:HGNC:47403 +106481896 RNU6-449P HGNC:HGNC:47412 +106481897 RNU6-461P HGNC:HGNC:47424 +106481898 RNU6-486P HGNC:HGNC:47449 +106481899 RNU6-502P HGNC:HGNC:47465 +106481900 RNU6-521P HGNC:HGNC:47484 +106481901 RNU6-533P HGNC:HGNC:47496 +106481902 RNU6-547P HGNC:HGNC:47510 +106481903 RNU6-566P HGNC:HGNC:47529 +106481904 RNU6-578P HGNC:HGNC:47541 +106481905 RNU6-597P HGNC:HGNC:47560 +106481906 RNU6-609P HGNC:HGNC:47572 +106481907 RNU6-621P HGNC:HGNC:47584 +106481908 RNU6-641P HGNC:HGNC:47604 +106481909 RNU6-654P HGNC:HGNC:47617 +106481910 RNU6-672P HGNC:HGNC:47635 +106481911 RNU6-681P HGNC:HGNC:47644 +106481912 RNU6-702P HGNC:HGNC:47665 +106481913 RNU6-719P HGNC:HGNC:47682 +106481914 RNU6-737P HGNC:HGNC:47700 +106481915 RNU6-755P HGNC:HGNC:47718 +106481916 RNU6-767P HGNC:HGNC:47730 +106481917 RNU6-782P HGNC:HGNC:47745 +106481918 RNU6-836P HGNC:HGNC:47799 +106481919 RNU6-850P HGNC:HGNC:47813 +106481920 RNU6-862P HGNC:HGNC:47825 +106481921 RNU6-883P HGNC:HGNC:47846 +106481922 RNU6-896P HGNC:HGNC:47859 +106481923 RNU6-915P HGNC:HGNC:47878 +106481924 RNU6-936P HGNC:HGNC:47899 +106481925 RNU6-949P HGNC:HGNC:47912 +106481926 RNU6-971P HGNC:HGNC:47934 +106481927 RNU6-984P HGNC:HGNC:47947 +106481928 RNU6-996P HGNC:HGNC:47959 +106481929 RNU6-1010P HGNC:HGNC:47973 +106481930 RNU6-1021P HGNC:HGNC:47984 +106481931 RNU6-1039P HGNC:HGNC:48002 +106481932 RNU6-1051P HGNC:HGNC:48014 +106481933 RNU6-1068P HGNC:HGNC:48031 +106481934 RNU6-1086P HGNC:HGNC:48049 +106481935 RNU6-1098P HGNC:HGNC:48061 +106481936 RNU6-1122P HGNC:HGNC:48085 +106481937 RNU6-1132P HGNC:HGNC:48095 +106481938 RNU6-1144P HGNC:HGNC:48107 +106481939 RNU6-1159P HGNC:HGNC:48122 +106481940 RNU6-1171P HGNC:HGNC:48134 +106481941 RNU6-1183P HGNC:HGNC:48146 +106481942 RNU6-1201P HGNC:HGNC:48164 +106481943 RNU6-1212P HGNC:HGNC:48175 +106481944 RNU6-1230P HGNC:HGNC:48193 +106481945 RNU6-1244P HGNC:HGNC:48207 +106481946 RNU6-1255P HGNC:HGNC:48218 +106481947 RNU6-1273P HGNC:HGNC:48236 +106481948 RNU6-1285P HGNC:HGNC:48248 +106481949 RNU6-1303P HGNC:HGNC:48266 +106481950 RNU6-1315P HGNC:HGNC:48278 +106481951 RNU6-1326P HGNC:HGNC:48289 +106481952 RNU1-7P HGNC:HGNC:48306 +106481953 RNU1-39P HGNC:HGNC:48381 +106481954 RNU1-55P HGNC:HGNC:48397 +106481955 RNU1-72P HGNC:HGNC:48414 +106481956 RNU1-94P HGNC:HGNC:48436 +106481957 RNU1-108P HGNC:HGNC:48450 +106481958 RNU1-132P HGNC:HGNC:48474 +106481959 RNU2-19P HGNC:HGNC:48512 +106481960 RNU2-34P HGNC:HGNC:48527 +106481961 RNU2-55P HGNC:HGNC:48548 +106481962 RNU2-68P HGNC:HGNC:48561 +106481963 DPPA3P3 HGNC:HGNC:49062 +106481964 ELOCP32 HGNC:HGNC:49173 +106481965 COX6CP16 HGNC:HGNC:49367 +106481966 BNIP3P28 HGNC:HGNC:49708 +106481967 NOP56P3 HGNC:HGNC:49801 +106481968 B3GNTL1P1 HGNC:HGNC:51317 +106481969 WBP1LP11 HGNC:HGNC:51471 +106481970 DUX4L29 HGNC:HGNC:51606 +106481971 RPL23AP94 HGNC:HGNC:51629 +106481972 RARRES2P10 HGNC:HGNC:51742 +106481973 RNU6-12P HGNC:HGNC:34256 +106481974 RN7SKP47 HGNC:HGNC:45771 +106481975 RN7SL45P HGNC:HGNC:46061 +106481976 RN7SL567P HGNC:HGNC:46583 +106481977 RNU6-139P HGNC:HGNC:47102 +106481978 RNU6-534P HGNC:HGNC:47497 +106481979 RNU6-982P HGNC:HGNC:47945 +106481980 RNU1-61P HGNC:HGNC:48403 +106481981 ZNF519P4 HGNC:HGNC:50788 +106501712 LOC106501712 - +106501713 LOC106501713 - +106560211 LOC106560211 - +106614088 MIR34AHG HGNC:HGNC:51913|Ensembl:ENSG00000228526 +106627981 LOC106627981 - +106627982 LOC106627982 - +106631777 RNA45SN1 HGNC:HGNC:53514 +106631778 RNA45S3 HGNC:HGNC:44276 +106631779 RNA45S2 HGNC:HGNC:44275 +106631780 RNA45S1 HGNC:HGNC:44274 +106631781 RNA18SN1 HGNC:HGNC:53515 +106631782 RNA18S3 HGNC:HGNC:44280 +106632258 RNA18S2 HGNC:HGNC:44279 +106632259 RNA18S1 HGNC:HGNC:44278 +106632260 RNA5-8SN1 HGNC:HGNC:53517 +106632261 RNA5-8S3 HGNC:HGNC:44284 +106632262 RNA5-8S2 HGNC:HGNC:44283 +106632263 RNA5-8S1 HGNC:HGNC:44282 +106632264 RNA28SN1 HGNC:HGNC:53516 +106632265 RNA28S3 HGNC:HGNC:44288 +106632266 RNA28S2 HGNC:HGNC:44287 +106632267 RNA28S1 HGNC:HGNC:44286 +106632268 APOB3'MAR - +106632269 CCDC58P4 HGNC:HGNC:45027 +106632270 DUX4L35 HGNC:HGNC:51773 +106632271 SNORD128 HGNC:HGNC:50409 +106633800 SNORD133 HGNC:HGNC:50414 +106633801 SCARNA28 HGNC:HGNC:50388 +106633802 RN7SKP118 HGNC:HGNC:45842 +106633803 SNORD134 HGNC:HGNC:50415 +106633804 SNORD135 HGNC:HGNC:50416 +106633805 SNORD136 HGNC:HGNC:50417 +106633806 SNORD142 HGNC:HGNC:50389 +106633807 RN7SKP251 HGNC:HGNC:45975 +106633808 SNORD143 HGNC:HGNC:50400 +106633809 SNORD144 HGNC:HGNC:50401 +106633810 SCARNA26A HGNC:HGNC:50385 +106633812 APOB-ICR - +106633813 SIRT1-AS HGNC:HGNC:51912 +106633814 SNORA86 HGNC:HGNC:50390 +106633815 RNU6-205P HGNC:HGNC:47168 +106633816 SCARNA26B HGNC:HGNC:51394 +106635520 SNORA87 HGNC:HGNC:50391 +106635521 SNORA88 HGNC:HGNC:50392 +106635522 SNORA89 HGNC:HGNC:50393 +106635523 SNORA90 HGNC:HGNC:50394 +106635524 SNORA91 HGNC:HGNC:50395 +106635525 SNORA92 HGNC:HGNC:50396 +106635526 SNORA93 HGNC:HGNC:50397 +106635527 LINC01323 HGNC:HGNC:50529 +106635528 SNORA94 HGNC:HGNC:50398 +106635529 SNORA95 HGNC:HGNC:50399 +106635530 SNORA98 HGNC:HGNC:50402 +106635531 SNORA99 HGNC:HGNC:50403 +106635532 SNORA100 HGNC:HGNC:50404 +106635533 SNORA103 HGNC:HGNC:51395 +106635534 SNORA104 HGNC:HGNC:51396 +106635535 RN7SKP173 HGNC:HGNC:45897 +106635536 RN7SKP176 HGNC:HGNC:45900 +106635537 RN7SL860P HGNC:HGNC:46876 +106635539 SNORA105A HGNC:HGNC:51397 +106635540 SNORA105B HGNC:HGNC:51398 +106635541 SNORA105C HGNC:HGNC:51399 +106635542 SNORA107 HGNC:HGNC:51400 +106635543 SNORA108 HGNC:HGNC:51401 +106635544 SNORA109 HGNC:HGNC:51402 +106635545 SNORA110 HGNC:HGNC:51403 +106635546 SNORA111 HGNC:HGNC:51404 +106635547 SNORD129 HGNC:HGNC:50410 +106635548 SNORD130 HGNC:HGNC:50411 +106635549 SNORD131 HGNC:HGNC:50412 +106635550 SNORD132 HGNC:HGNC:50413 +106635615 SNORD137 HGNC:HGNC:50419 +106635682 SNORD140 HGNC:HGNC:51405 +106635683 SNORD141A HGNC:HGNC:51406 +106635684 SNORD141B HGNC:HGNC:51407 +106660605 MIR2117HG HGNC:HGNC:51999 +106660606 LOC106660606 Ensembl:ENSG00000260778 +106660607 DUX4L42 HGNC:HGNC:51780 +106660608 ERVPRODH - +106660609 MIR4432HG HGNC:HGNC:52005|Ensembl:ENSG00000223929 +106660610 MIR5689HG HGNC:HGNC:52007|Ensembl:ENSG00000229401 +106660611 RNU2-22P HGNC:HGNC:48515 +106660612 LINC00680 HGNC:HGNC:44417|Ensembl:ENSG00000215190 +106660613 LINC00680-GUSBP4 Ensembl:ENSG00000283352 +106660614 EGLN1P1 HGNC:HGNC:44481 +106660616 SAP18P3 HGNC:HGNC:51569 +106660617 DUX4L43 HGNC:HGNC:51781 +106660618 MCDR5 HGNC:HGNC:49649 +106660619 TP53TG3GP HGNC:HGNC:51818 +106660620 RARRES2P9 HGNC:HGNC:48708 +106660623 CNTNAP3P3 HGNC:HGNC:49580 +106660625 LOC106660625 - +106660633 MTATP6P6 HGNC:HGNC:44580 +106677019 LOC106677019 - +106694315 LOC106694315 - +106694316 LOC106694316 - +106699567 LOC106699567 - +106699568 ERVW-9 HGNC:HGNC:49248 +106699570 LOC106699570 Ensembl:ENSG00000246777 +106699575 DUP14Q32 MIM:616604 +106699576 RC14S MIM:616606 +106707172 LOC106707172 - +106707173 LOC106707173 - +106707174 LOC106707174 - +106707175 ERVK-28 HGNC:HGNC:44981 +106707243 PRH1-TAS2R14 - +106721785 LOC106721785 - +106728414 LOC106728414 - +106728418 LOC106728418 - +106736464 LOC106736464 - +106736465 LOC106736465 - +106736468 LOC106736468 - +106736469 LOC106736469 - +106736470 LOC106736470 - +106736475 PCF11-AS1 HGNC:HGNC:52263 +106736476 LOC106736476 - +106736477 LOC106736477 - +106736480 LOC106736480 - +106736481 LOC106736481 - +106736613 MCS+9.7 - +106736614 LOC106736614 - +106780800 LOC106780800 - +106780802 KCNK4-TEX40 Ensembl:ENSG00000257069 +106780803 LOC106780803 - +106780804 LOC106780804 - +106780824 LOC106780824 - +106780825 LOC106780825 - +106783492 LOC106783492 - +106783493 LOC106783493 - +106783494 LOC106783494 - +106783495 LOC106783495 - +106783496 LOC106783496 - +106783497 LOC106783497 - +106783498 LOC106783498 - +106783499 OPA8 MIM:616648|HGNC:HGNC:39750 +106783500 LOC106783500 - +106783501 LOC106783501 - +106783502 LOC106783502 - +106783503 LOC106783503 - +106783504 LOC106783504 - +106783505 LOC106783505 - +106783506 LOC106783506 - +106783507 LOC106783507 - +106783508 LOC106783508 - +106783509 LOC106783509 - +106783574 LOC106783574 - +106783575 LOC106783575 - +106783576 LOC106783576 - +106794091 LOC106794091 - +106794092 LOC106794092 - +106799832 LOC106799832 - +106799833 LOC106799833 - +106799834 LOC106799834 - +106799835 LOC106799835 - +106799836 LOC106799836 - +106799837 LOC106799837 - +106799838 LOC106799838 - +106799839 LOC106799839 - +106799840 LOC106799840 - +106799841 LOC106799841 - +106799842 LOC106799842 - +106799843 LOC106799843 - +106799844 LOC106799844 - +106799845 LOC106799845 - +106799846 LOC106799846 - +106799848 LOC106799848 - +106799849 LOC106799849 - +106799914 YUHAL MIM:616652 +106799915 LOC106799915 - +106804089 LOC106804089 - +106804547 LOC106804547 - +106804612 LOC106804612 - +106804613 LOC106804613 - +106821730 BUB1B-PAK6 HGNC:HGNC:52276|Ensembl:ENSG00000259288|Vega:OTTHUMG00000172398 +106865367 MRD2 MIM:614113 +106865368 LOC106865368 - +106865369 LOC106865369 - +106865372 RNU6-146P HGNC:HGNC:47109 +106865373 WRB-SH3BGR - +106865374 RNU6-468P HGNC:HGNC:47431 +106865375 RNA5SP334 HGNC:HGNC:43234 +106866913 RN7SL431P HGNC:HGNC:46447 +106866914 RNU6-1240P HGNC:HGNC:48203 +106866915 RNU1-125P HGNC:HGNC:48467 +106866980 RNU2-15P HGNC:HGNC:48508 +106866981 RNU6-244P HGNC:HGNC:47207 +106866982 DES-LCR - +106867047 LOC106867047 - +106903081 DUSP8P5 HGNC:HGNC:45003 +106903146 LOC106903146 - +106992256 LOC106992256 - +107001062 LOC107001062 - +107001063 LOC107001063 - +107032760 LOC107032760 - +107032825 LOC107032825 - +107048980 DSPS MIM:614163 +107048981 RN7SL731P HGNC:HGNC:46747 +107048982 LOC107048982 - +107048983 RNU1-149P HGNC:HGNC:48491 +107048984 LOC107048984 - +107048985 RNU4-46P HGNC:HGNC:46982 +107057644 RN7SKP70 HGNC:HGNC:45794 +107057645 LOC107057645 - +107057646 RNU4-22P HGNC:HGNC:46958 +107057647 RNU6-112P HGNC:HGNC:47075 +107063536 RN7SKP241 HGNC:HGNC:45965 +107063537 RNU6-669P HGNC:HGNC:47632 +107063538 AHCYP8 HGNC:HGNC:45000 +107063539 RN7SL75P HGNC:HGNC:46091 +107063540 RNU6-914P HGNC:HGNC:47877 +107063541 CYP2C63P HGNC:HGNC:42411 +107063542 ORS8 - +107063543 CYP3A137P HGNC:HGNC:42419 +107063544 RNU7-103P HGNC:HGNC:45637 +107063609 KAOGS MIM:608149 +107063610 LOC107063610 - +107063611 MTND6P24 HGNC:HGNC:51982 +107063612 RNU6-941P HGNC:HGNC:47904 +107074708 RN7SL657P HGNC:HGNC:46673 +107075092 NDUFB4P4 HGNC:HGNC:45252 +107075094 NDUFB4P7 HGNC:HGNC:45255 +107075096 NDUFB4P5 HGNC:HGNC:45253 +107075097 NDUFB4P6 HGNC:HGNC:45254 +107075098 MTND4LP2 HGNC:HGNC:42236 +107075099 MTND4LP10 HGNC:HGNC:42244 +107075100 MTND4LP13 HGNC:HGNC:42247 +107075101 MTND4LP18 HGNC:HGNC:42252 +107075102 MTND4LP22 HGNC:HGNC:42256 +107075103 MTND4LP24 HGNC:HGNC:42258 +107075104 MTND4LP26 HGNC:HGNC:42260 +107075105 NDUFB4P10 HGNC:HGNC:45258 +107075106 RHOXF1P2 HGNC:HGNC:51611 +107075107 SEPT14P21 HGNC:HGNC:51712 +107075108 SLC47A1P1 HGNC:HGNC:51849 +107075109 RPSAP65 HGNC:HGNC:51914 +107075110 RPSAP66 HGNC:HGNC:51916 +107075111 RPSAP67 HGNC:HGNC:51918 +107075112 RPSAP72 HGNC:HGNC:51925 +107075113 RPSAP74 HGNC:HGNC:51928 +107075114 RPSAP75 HGNC:HGNC:51929 +107075115 RPL12P47 HGNC:HGNC:51939 +107075116 MIR3142HG HGNC:HGNC:51944|Ensembl:ENSG00000253522 +107075117 MTND4P35 HGNC:HGNC:51949 +107075118 MTND5P33 HGNC:HGNC:51952 +107075119 MTND5P35 HGNC:HGNC:51954 +107075120 MTCYBP14 HGNC:HGNC:51960 +107075121 MTCYBP10 HGNC:HGNC:51961 +107075122 MTCYBP11 HGNC:HGNC:51962 +107075123 MTCYBP12 HGNC:HGNC:51963 +107075124 MTCYBP9 HGNC:HGNC:51966 +107075125 MTCYBP5 HGNC:HGNC:51967 +107075126 MTCYBP16 HGNC:HGNC:51969 +107075127 MTCYBP19 HGNC:HGNC:51971 +107075128 MTCYBP20 HGNC:HGNC:51973 +107075129 MTCYBP13 HGNC:HGNC:51975 +107075130 MTCYBP18 HGNC:HGNC:51976 +107075131 MTCYBP23 HGNC:HGNC:51980 +107075132 MTCYBP24 HGNC:HGNC:51983 +107075133 MTCYBP27 HGNC:HGNC:51993 +107075134 MTCYBP28 HGNC:HGNC:51994 +107075135 MTCYBP29 HGNC:HGNC:51995 +107075136 MTCYBP31 HGNC:HGNC:51997 +107075137 MTCO1P6 HGNC:HGNC:52008 +107075138 MTCO1P8 HGNC:HGNC:52010 +107075139 MTCO1P9 HGNC:HGNC:52011 +107075140 MTCO1P10 HGNC:HGNC:52012 +107075141 MTCO1P12 HGNC:HGNC:52014 +107075142 MTCO1P14 HGNC:HGNC:52016 +107075143 MTCO1P18 HGNC:HGNC:52020 +107075144 MTCO1P19 HGNC:HGNC:52021 +107075145 MTCO2P7 HGNC:HGNC:52023 +107075146 MTCO2P8 HGNC:HGNC:52024 +107075147 MTCO2P15 HGNC:HGNC:52031 +107075148 MTCO2P16 HGNC:HGNC:52032 +107075149 MTCO2P18 HGNC:HGNC:52034 +107075150 MTCO3P7 HGNC:HGNC:52037 +107075151 MTCO3P8 HGNC:HGNC:52038 +107075152 MTCO3P10 HGNC:HGNC:52040 +107075153 MTCO3P11 HGNC:HGNC:52041 +107075154 MTCO3P15 HGNC:HGNC:52045 +107075155 MTCO3P16 HGNC:HGNC:52046 +107075156 MTCO3P19 HGNC:HGNC:52049 +107075157 MTATP6P14 HGNC:HGNC:52059 +107075158 MTATP6P16 HGNC:HGNC:52061 +107075159 MTATP6P18 HGNC:HGNC:52063 +107075160 MTND3P12 HGNC:HGNC:52072 +107075161 MTND3P19 HGNC:HGNC:52081 +107075162 MTCO3P21 HGNC:HGNC:52083 +107075163 MTCO1P20 HGNC:HGNC:52085 +107075164 MTCO1P21 HGNC:HGNC:52086 +107075165 MTCO1P22 HGNC:HGNC:52087 +107075166 MTCO1P24 HGNC:HGNC:52089 +107075167 MTCO1P25 HGNC:HGNC:52090 +107075168 MTCO1P27 HGNC:HGNC:52092 +107075169 MTCO1P28 HGNC:HGNC:52093 +107075170 MTCO1P30 HGNC:HGNC:52095 +107075171 MTCO1P31 HGNC:HGNC:52096 +107075172 MTCO1P40 HGNC:HGNC:52105 +107075173 MTCO1P43 HGNC:HGNC:52108 +107075174 MTCO1P45 HGNC:HGNC:52110 +107075175 MTCO1P46 HGNC:HGNC:52111 +107075176 MTCO1P48 HGNC:HGNC:52113 +107075177 MTCO1P49 HGNC:HGNC:52114 +107075178 MTCO1P54 HGNC:HGNC:52119 +107075179 MTCO1P55 HGNC:HGNC:52120 +107075180 MTCO3P20 HGNC:HGNC:52122 +107075181 MTCO2P5 HGNC:HGNC:52124 +107075182 MTCO3P23 HGNC:HGNC:52126 +107075183 MTCO3P27 HGNC:HGNC:52130 +107075184 MTCO3P28 HGNC:HGNC:52131 +107075185 MTCO3P29 HGNC:HGNC:52132 +107075186 MTCO3P31 HGNC:HGNC:52134 +107075187 MTCO3P38 HGNC:HGNC:52141 +107075188 MTCO3P40 HGNC:HGNC:52143 +107075189 MTCO3P42 HGNC:HGNC:52145 +107075190 MTCO3P43 HGNC:HGNC:52146 +107075191 MTCO2P21 HGNC:HGNC:52150 +107075192 MTCO2P23 HGNC:HGNC:52152 +107075193 MTCO2P24 HGNC:HGNC:52153 +107075194 MTCO2P29 HGNC:HGNC:52158 +107075195 MTCO2P30 HGNC:HGNC:52159 +107075196 MTCO2P32 HGNC:HGNC:52161 +107075197 MTCO2P33 HGNC:HGNC:52162 +107075198 MTND3P21 HGNC:HGNC:52167 +107075199 MTND3P24 HGNC:HGNC:52170 +107075200 MTND6P32 HGNC:HGNC:52173 +107075201 MTATP6P20 HGNC:HGNC:52176 +107075202 MTATP6P22 HGNC:HGNC:52178 +107075203 MTATP6P25 HGNC:HGNC:52181 +107075204 MTATP6P27 HGNC:HGNC:52183 +107075205 MTATP6P31 HGNC:HGNC:52186 +107075207 NDUFA8P1 HGNC:HGNC:52264 +107075208 NDUFB2P1 HGNC:HGNC:52266 +107075209 NDUFS6P1 HGNC:HGNC:52274 +107075210 MTND4LP16 HGNC:HGNC:42250 +107075211 NDUFB4P9 HGNC:HGNC:45257 +107075212 RPL12P50 HGNC:HGNC:51942 +107075213 MTCYBP17 HGNC:HGNC:51970 +107075214 MTCO2P11 HGNC:HGNC:52027 +107075215 MTCO3P18 HGNC:HGNC:52048 +107075216 MTCO3P4 HGNC:HGNC:52079 +107075217 MTCO3P24 HGNC:HGNC:52127 +107075218 MTCO3P45 HGNC:HGNC:52148 +107075219 LAPTM4BP2 HGNC:HGNC:51935 +107075220 MTCYBP8 HGNC:HGNC:51965 +107075221 MTCYBP22 HGNC:HGNC:51979 +107075222 MTCO1P17 HGNC:HGNC:52019 +107075223 MTCO2P19 HGNC:HGNC:52035 +107075224 MTCO3P13 HGNC:HGNC:52043 +107075225 MTCO1P29 HGNC:HGNC:52094 +107075226 MTCO1P44 HGNC:HGNC:52109 +107075227 MTCO1P52 HGNC:HGNC:52117 +107075228 MTCO3P5 HGNC:HGNC:52123 +107075229 MTCO3P30 HGNC:HGNC:52133 +107075230 MTCO2P20 HGNC:HGNC:52149 +107075231 MTCYBP32 HGNC:HGNC:52174 +107075232 MTATP6P24 HGNC:HGNC:52180 +107075233 NDUFB9P1 HGNC:HGNC:52269 +107075234 MTCO1P35 HGNC:HGNC:52100 +107075235 MTND4LP5 HGNC:HGNC:42239 +107075236 MTND4LP7 HGNC:HGNC:42241 +107075237 MTND4LP9 HGNC:HGNC:42243 +107075238 MTND4LP11 HGNC:HGNC:42245 +107075239 MTND4LP12 HGNC:HGNC:42246 +107075240 MTND4LP17 HGNC:HGNC:42251 +107075241 MTND4LP19 HGNC:HGNC:42253 +107075242 MTND4LP20 HGNC:HGNC:42254 +107075243 MTND4LP25 HGNC:HGNC:42259 +107075244 MTND4LP30 HGNC:HGNC:42264 +107075245 MTND4LP3 HGNC:HGNC:42265 +107075246 NDUFB4P8 HGNC:HGNC:45256 +107075247 NDUFB4P11 HGNC:HGNC:45259 +107075248 RARRES2P11 HGNC:HGNC:51743 +107075249 RPSAP71 HGNC:HGNC:51924 +107075250 RPSAP73 HGNC:HGNC:51926 +107075251 RPL12P46 HGNC:HGNC:51938 +107075252 RPL12P49 HGNC:HGNC:51941 +107075253 MTND4P33 HGNC:HGNC:51947 +107075254 MTND5P32 HGNC:HGNC:51951 +107075255 MTND5P34 HGNC:HGNC:51953 +107075256 MTND5P40 HGNC:HGNC:51959 +107075257 MTCYBP7 HGNC:HGNC:51964 +107075258 MTCYBP15 HGNC:HGNC:51968 +107075259 MTCYBP6 HGNC:HGNC:51974 +107075260 MTCYBP21 HGNC:HGNC:51977 +107075261 MTND6P22 HGNC:HGNC:51978 +107075262 MTND6P25 HGNC:HGNC:51984 +107075263 MTCO1P7 HGNC:HGNC:52009 +107075264 MTCO1P11 HGNC:HGNC:52013 +107075265 MTCO1P15 HGNC:HGNC:52017 +107075266 MTCO2P6 HGNC:HGNC:52022 +107075267 MTCO2P9 HGNC:HGNC:52025 +107075268 MTCO2P17 HGNC:HGNC:52033 +107075269 MTCO3P9 HGNC:HGNC:52039 +107075270 MTCO3P12 HGNC:HGNC:52042 +107075271 MTCO3P17 HGNC:HGNC:52047 +107075272 MTATP6P13 HGNC:HGNC:52058 +107075273 MTATP6P15 HGNC:HGNC:52060 +107075274 MTATP6P17 HGNC:HGNC:52062 +107075275 MTATP6P19 HGNC:HGNC:52064 +107075276 MTND2P38 HGNC:HGNC:52069 +107075277 MTND3P13 HGNC:HGNC:52073 +107075278 MTND3P16 HGNC:HGNC:52076 +107075279 MTND3P17 HGNC:HGNC:52077 +107075280 MTND2P40 HGNC:HGNC:52084 +107075281 MTCO1P23 HGNC:HGNC:52088 +107075282 MTCO1P39 HGNC:HGNC:52104 +107075283 MTCO1P42 HGNC:HGNC:52107 +107075284 MTCO1P47 HGNC:HGNC:52112 +107075285 MTCO1P53 HGNC:HGNC:52118 +107075286 MTCO1P56 HGNC:HGNC:52121 +107075287 MTCO3P35 HGNC:HGNC:52138 +107075288 MTCO3P41 HGNC:HGNC:52144 +107075289 MTCO3P44 HGNC:HGNC:52147 +107075290 MTCO2P25 HGNC:HGNC:52154 +107075291 MTCO2P27 HGNC:HGNC:52156 +107075292 MTCO2P31 HGNC:HGNC:52160 +107075293 MTCO3P46 HGNC:HGNC:52165 +107075294 MTND3P20 HGNC:HGNC:52166 +107075295 MTND3P23 HGNC:HGNC:52169 +107075296 MTND4LP31 HGNC:HGNC:52171 +107075297 MTND3P25 HGNC:HGNC:52172 +107075298 MTND6P33 HGNC:HGNC:52175 +107075299 MTATP6P21 HGNC:HGNC:52177 +107075300 MTATP6P23 HGNC:HGNC:52179 +107075301 MTATP6P26 HGNC:HGNC:52182 +107075302 MTATP6P30 HGNC:HGNC:52185 +107075303 NDUFAB1P1 HGNC:HGNC:52265 +107075304 NDUFB10P2 HGNC:HGNC:52273 +107075305 MTND4LP14 HGNC:HGNC:42248 +107075306 MTND4LP21 HGNC:HGNC:42255 +107075307 RHOXF1P3 HGNC:HGNC:51612 +107075308 MTND4P34 HGNC:HGNC:51948 +107075309 MTND5P41 HGNC:HGNC:51972 +107075310 MTCO2P12 HGNC:HGNC:52028 +107075311 MTATP6P11 HGNC:HGNC:52057 +107075312 MTND2P39 HGNC:HGNC:52070 +107075313 MTCO3P39 HGNC:HGNC:52142 +107075314 MTND3P22 HGNC:HGNC:52168 +107075315 MTATP6P29 HGNC:HGNC:52187 +107075316 DUX4L32 HGNC:HGNC:51771 +107075317 LOC107075317 - +107075318 RNU6-707P HGNC:HGNC:47670 +107075319 RN7SL151P HGNC:HGNC:46167 +107080107 MTATP8P4 HGNC:HGNC:44574 +107080108 DUX4L37 HGNC:HGNC:51775 +107080551 DUX4L33 HGNC:HGNC:51789 +107080552 LOC107080552 - +107080553 PCMTD1P7 HGNC:HGNC:51751 +107080554 LINC01400 HGNC:HGNC:50681 +107080555 LOC107080555 - +107080620 ODF2-AS1 HGNC:HGNC:49461 +107080621 LINC01077 HGNC:HGNC:49120 +107080622 USP9YP28 HGNC:HGNC:38764 +107080623 LINC01073 HGNC:HGNC:49114 +107080624 LINC01067 HGNC:HGNC:49105 +107080626 RN7SKP54 HGNC:HGNC:45778 +107080627 IQCA1-AS1 HGNC:HGNC:41137 +107080628 RNU1-48P HGNC:HGNC:48390 +107080629 RNU2-52P HGNC:HGNC:48545 +107080632 RN7SL68P HGNC:HGNC:46084 +107080633 CFTRP2 HGNC:HGNC:51351 +107080636 RN7SL417P HGNC:HGNC:46433 +107080637 UPK3BP1 HGNC:HGNC:42353 +107080638 TBC1D7-LOC100130357 Ensembl:ENSG00000145979|Vega:OTTHUMG00000014272 +107080639 ANKRD62P1 HGNC:HGNC:42363 +107080641 CYP4A26P HGNC:HGNC:39980 +107080642 DUX4L36 HGNC:HGNC:51774 +107080644 CNPY3-GNMT - +107080645 DUX4L39 HGNC:HGNC:51777 +107080646 5'URS - +107080648 DUX4L38 HGNC:HGNC:51776 +107080649 DUX4L40 HGNC:HGNC:51778 +107080650 DUX4L41 HGNC:HGNC:51779 +107080651 DUX4L44 HGNC:HGNC:51782 +107080652 RN7SL736P HGNC:HGNC:46752 +107080653 RN7SL796P HGNC:HGNC:46812 +107080654 RN7SL825P HGNC:HGNC:46841 +107080655 RNU4-33P HGNC:HGNC:46969 +107105251 DUX4L48 HGNC:HGNC:51786 +107105252 DUX4L49 HGNC:HGNC:51787 +107105253 RNU6-322P HGNC:HGNC:47285 +107105254 RNU6-799P HGNC:HGNC:47762 +107105255 PCMTD1P6 HGNC:HGNC:51750 +107105256 RNU6-1055P HGNC:HGNC:48018 +107105257 PCMTD1P8 HGNC:HGNC:51752 +107105258 PCMTD1P4 HGNC:HGNC:51748 +107105259 RNU6-1108P HGNC:HGNC:48071 +107105260 PCMTD1P5 HGNC:HGNC:51749 +107105261 RNU1-5P HGNC:HGNC:48304 +107105262 RNU1-41P HGNC:HGNC:48383 +107105263 SEPT14P2 HGNC:HGNC:51686 +107105264 RNU1-70P HGNC:HGNC:48412 +107105265 SEPT14P3 HGNC:HGNC:51687 +107105266 SEPT14P4 HGNC:HGNC:51688 +107105267 MTCO1P26 HGNC:HGNC:52091 +107105268 MTCO1P32 HGNC:HGNC:52097 +107105269 MTCO1P33 HGNC:HGNC:52098 +107105270 MTCO1P34 HGNC:HGNC:52099 +107105271 SEPT14P19 HGNC:HGNC:51707 +107105272 MTCO1P36 HGNC:HGNC:52101 +107105273 MTCO1P37 HGNC:HGNC:52102 +107105274 MTCO1P38 HGNC:HGNC:52103 +107105276 SEPT14P5 HGNC:HGNC:51689 +107105277 MTCO1P41 HGNC:HGNC:52106 +107105278 SEPT14P6 HGNC:HGNC:51690 +107105279 MTCO1P50 HGNC:HGNC:52115 +107105280 SEPT14P7 HGNC:HGNC:51691 +107105281 MTCO1P13 HGNC:HGNC:52015 +107105282 LOC107105282 - +107105283 MTCO1P16 HGNC:HGNC:52018 +107105350 LOC107105350 - +107105352 SEPT14P10 HGNC:HGNC:51697 +107105353 SEPT14P11 HGNC:HGNC:51698 +107105354 SEPT14P14 HGNC:HGNC:51701 +107126281 LOC107126281 - +107126282 SEPT14P15 HGNC:HGNC:51702 +107126283 SEPT14P16 HGNC:HGNC:51704 +107126284 SEPT14P18 HGNC:HGNC:51705 +107126285 SEPT14P20 HGNC:HGNC:51706 +107126286 SEPT14P22 HGNC:HGNC:51708 +107126287 BCRP9 HGNC:HGNC:49113 +107126288 LOC107126288 - +107126289 SLC25A39P2 HGNC:HGNC:48936 +107126290 SEPT14P23 HGNC:HGNC:51709 +107126294 CYP4F60P HGNC:HGNC:42468 +107126359 LOC107126359 - +107126360 AOX3P HGNC:HGNC:19049 +107126361 CD2-LCR - +107126362 MTCO2P28 HGNC:HGNC:52157 +107131119 MTATP6P8 HGNC:HGNC:44582 +107131120 MTND4LP4 HGNC:HGNC:42238 +107131121 MTND4LP6 HGNC:HGNC:42240 +107131122 RNU6-29P HGNC:HGNC:34273 +107131123 MTND4LP15 HGNC:HGNC:42249 +107131124 MTND4LP8 HGNC:HGNC:42242 +107133486 CDK2AP2P2 HGNC:HGNC:38493 +107133487 MTND4LP23 HGNC:HGNC:42257 +107133488 MTND4LP27 HGNC:HGNC:42261 +107133489 MTND4LP28 HGNC:HGNC:42262 +107133490 MTND4LP29 HGNC:HGNC:42263 +107133491 MTND5P36 HGNC:HGNC:51955 +107133493 MTND5P37 HGNC:HGNC:51956 +107133494 CYP4F27P HGNC:HGNC:39946 +107133495 MTND5P38 HGNC:HGNC:51957 +107133496 MTND5P39 HGNC:HGNC:51958 +107133497 CYP4F32P HGNC:HGNC:39951 +107133498 MTND6P23 HGNC:HGNC:51981 +107133499 CYP4F33P HGNC:HGNC:39952 +107133500 MTND6P26 HGNC:HGNC:51985 +107133501 MTND6P27 HGNC:HGNC:51986 +107133502 USP9YP14 HGNC:HGNC:38748 +107133503 MTND6P28 HGNC:HGNC:51987 +107133504 MTND6P29 HGNC:HGNC:51988 +107133505 MTND6P30 HGNC:HGNC:51989 +107133507 MTND6P31 HGNC:HGNC:51990 +107133508 RNA5SP387 HGNC:HGNC:43287 +107133509 LOC107133509 - +107133510 LOC107133510 - +107133511 ENPP7P6 HGNC:HGNC:48698 +107133513 KRT18P64 HGNC:HGNC:48891 +107133515 LOC107133515 - +107133516 SMURF2P1 HGNC:HGNC:44402 +107133517 LOC107133517 - +107133518 LOC107133518 - +107133519 PSAT1P2 HGNC:HGNC:43988 +107133522 DHX40P1 HGNC:HGNC:20687 +107133523 ELOCP27 HGNC:HGNC:31692 +107133524 PARP4P3 HGNC:HGNC:274 +107161144 DTX2P1 HGNC:HGNC:42352 +107161145 PMS2P11 HGNC:HGNC:9125 +107161146 MTND2P34 HGNC:HGNC:52065 +107161147 MTND2P35 HGNC:HGNC:52066 +107161148 MTND2P36 HGNC:HGNC:52067 +107161150 MTND2P37 HGNC:HGNC:52068 +107161151 AOX3P-AOX2P - +107161153 MTCO2P10 HGNC:HGNC:52026 +107161154 PGBD4P1 HGNC:HGNC:44066 +107161156 LOC107161156 - +107161157 YAM1 HGNC:HGNC:49034 +107161159 LINC02415 HGNC:HGNC:53344|Ensembl:ENSG00000248703 +107161160 MTND3P11 HGNC:HGNC:52071 +107161161 MTND3P14 HGNC:HGNC:52074 +107161162 MTND3P15 HGNC:HGNC:52075 +107161163 NPAP1P7 HGNC:HGNC:51473 +107161164 MTND3P18 HGNC:HGNC:52078 +107161229 MTATP8P3 HGNC:HGNC:44573 +107161230 CLUHP10 HGNC:HGNC:51574 +107178918 LINC01593 HGNC:HGNC:51583|Ensembl:ENSG00000231221 +107178919 RNY3P15 HGNC:HGNC:50890 +107178920 LOC107178920 - +107181287 LOC107181287 - +107181288 LOC107181288 - +107181289 NBLST7 MIM:616792 +107181291 POP3 - +107195252 LOC107195252 - +107197952 LOC107197952 - +107197953 ORI6 - +107198087 LOC107198087 - +107198088 20MER1 - +107198089 20MER2 - +107228316 ORI343 - +107228317 NOA3 - +107228318 LOC107228318 - +107228383 LOC107228383 - +107275221 LOC107275221 - +107275222 LOC107275222 - +107275223 LOC107275223 - +107275224 LOC107275224 - +107275225 LOC107275225 - +107275226 LOC107275226 - +107282092 BOLA2-SMG1P6 HGNC:HGNC:53563|Ensembl:ENSG00000261740|Vega:OTTHUMG00000176715 +107303337 LOC107303337 - +107303338 LOC107303338 - +107303339 LOC107303339 - +107303340 LOC107303340 - +107303341 LOC107303341 - +107303342 LOC107303342 - +107303343 LOC107303343 - +107303344 SETDB2-PHF11 - +107305681 DHS6S1 MIM:616842 +107305683 LOC107305683 - +107305684 LOC107305684 - +107305685 LOC107305685 - +107305686 LOC107305686 - +107325936 LOC107325936 - +107325941 LOC107325941 - +107325942 LOC107325942 - +107372315 LOC107372315 - +107397391 SCARNA21B HGNC:HGNC:52237 +107397392 SCARNA18B HGNC:HGNC:52236|Ensembl:ENSG00000238754 +107399301 SNORA101A HGNC:HGNC:50405 +107399303 SNORA101B HGNC:HGNC:50406 +107403064 MTCYBP25 HGNC:HGNC:51991 +107403065 MTCYBP26 HGNC:HGNC:51992 +107403066 MTCYBP30 HGNC:HGNC:51996 +107403068 CYP4F31P HGNC:HGNC:39955 +107403069 MTATP6P10 HGNC:HGNC:52056 +107403070 MTATP6P28 HGNC:HGNC:52184 +107403071 MTATP6P12 HGNC:HGNC:52082 +107403073 MTATP6P5 HGNC:HGNC:44579 +107403074 MTND4P36 HGNC:HGNC:51950 +107403075 LOC107403075 - +107403078 C2orf69P5 HGNC:HGNC:51804 +107403079 WBP1LP9 HGNC:HGNC:51469 +107403080 LOC107403080 - +107403081 FAM183EP HGNC:HGNC:51332 +107403148 CNTNAP3P9 HGNC:HGNC:49587 +107403150 CNTNAP3P4 HGNC:HGNC:49581 +107403151 GTF2IP10 HGNC:HGNC:51722 +107403153 LOC107403153 - +107403154 GTF2IP15 HGNC:HGNC:51727 +107403156 GTF2IP17 HGNC:HGNC:51729 +107403157 GTF2IP19 HGNC:HGNC:51731 +107403163 MTCO2P26 HGNC:HGNC:52155 +107403164 LOC107403164 - +107403168 MTCO2P13 HGNC:HGNC:52029 +107403169 MTCO2P14 HGNC:HGNC:52030 +107403234 LOC107403234 - +107403235 MTCO3P6 HGNC:HGNC:52036 +107403236 MTCO3P14 HGNC:HGNC:52044 +107403237 MTCO3P3 HGNC:HGNC:52080 +107403240 MTCO3P25 HGNC:HGNC:52128 +107403241 MTCO3P26 HGNC:HGNC:52129 +107403242 LOC107403242 - +107436001 MTCO3P32 HGNC:HGNC:52135 +107436002 LOC107436002 - +107436003 MTCO3P33 HGNC:HGNC:52136 +107436004 MTCO3P34 HGNC:HGNC:52137 +107436006 MTCO3P36 HGNC:HGNC:52139 +107436007 MTCO3P37 HGNC:HGNC:52140 +107436008 LOC107436008 - +107436076 CYP2C23P HGNC:HGNC:39970 +107457584 LOC107457584 - +107457585 LOC107457585 - +107457586 LOC107457586 - +107457587 LOC107457587 - +107457588 CYP4F61P HGNC:HGNC:42469 +107457589 DEL16P13.2 MIM:616863 +107457596 LOC107457596 - +107457597 LOC107457597 - +107457599 LOC107457599 - +107457601 LOC107457601 - +107457602 LOC107457602 - +107521942 RNU1-79P HGNC:HGNC:48421 +107521946 RNU1-116P HGNC:HGNC:48458 +107521952 LOC107521952 - +107522028 LOC107522028 - +107522029 LOC107522029 - +107522030 LOC107522030 - +107522031 LOC107522031 - +107522035 LOC107522035 - +107522039 LOC107522039 - +107522105 DEL15Q14 MIM:616898 +107546745 LOC107546745 - +107546746 LOC107546746 - +107546747 LOC107546747 - +107546764 LINC01976 HGNC:HGNC:52803|Ensembl:ENSG00000261514 +107546778 LOC107546778 - +107546780 LOC107546780 - +107548099 IGHVII-30-21 HGNC:HGNC:52400|IMGT/GENE-DB:IGHV(II)-30-21 +107548103 LOC107548103 - +107548109 LOC107548109 - +107548111 LOC107548111 - +107548112 LOC107548112 - +107604627 OPSIN-LCR MIM:300824 +107648851 LOC107648851 - +107648856 LOC107648856 - +107648859 LOC107648859 - +107648861 DEL11P13 MIM:616902 +107648863 LOC107648863 - +107648864 LOC107648864 - +107648866 LOC107648866 - +107652445 LOC107652445 - +107758904 LOC107758904 - +107832851 LOC107832851 - +107832852 LOC107832852 - +107832854 LOC107832854 - +107832855 LOC107832855 - +107838685 LOC107838685 - +107880064 LOC107880064 - +107880065 ARMD10 MIM:611488 +107882126 LOC107882126 - +107882127 LOC107882127 - +107882129 LOC107882129 - +107882132 LOC107882132 - +107882133 LOC107882133 - +107963947 LOC107963947 - +107963948 LOC107963948 - +107963949 LOC107963949 - +107963950 LOC107963950 - +107963951 LOC107963951 - +107963955 LOC107963955 - +107966121 LOC107966121 - +107966124 RER - +107966125 LOC107966125 - +107980434 LOC107980434 - +107980440 LOC107980440 - +107980445 LOC107980445 - +107982234 LOC107982234 - +107983947 LOC107983947 - +107983948 LOC107983948 - +107983949 LOC107983949 - +107983950 LOC107983950 - +107983951 LOC107983951 - +107983952 LOC107983952 - +107983953 LOC107983953 - +107983954 LOC107983954 - +107983955 ELOA3C HGNC:HGNC:52410|Ensembl:ENSG00000275553|Vega:OTTHUMG00000188256 +107983956 LOC107983956 - +107983957 LOC107983957 - +107983958 LOC107983958 - +107983959 LOC107983959 - +107983960 LOC107983960 - +107983961 LOC107983961 - +107983962 LOC107983962 - +107983963 LOC107983963 - +107983964 LINC02128 HGNC:HGNC:52986 +107983966 LOC107983966 - +107983967 LOC107983967 - +107983968 LOC107983968 - +107983969 LOC107983969 - +107983970 LOC107983970 - +107983971 LOC107983971 - +107983972 LOC107983972 - +107983973 LOC107983973 - +107983974 LOC107983974 - +107983975 LOC107983975 - +107983976 LOC107983976 - +107983977 LOC107983977 - +107983978 LOC107983978 - +107983979 LOC107983979 - +107983980 LOC107983980 - +107983981 LOC107983981 - +107983982 LOC107983982 - +107983983 LOC107983983 - +107983984 LOC107983984 - +107983985 LOC107983985 - +107983986 LOC107983986 - +107983987 LOC107983987 Ensembl:ENSG00000278961|Vega:OTTHUMG00000189413 +107983988 LOC107983988 Ensembl:ENSG00000283439|Vega:OTTHUMG00000191681 +107983989 LOC107983989 - +107983990 LOC107983990 Ensembl:ENSG00000197302|Vega:OTTHUMG00000167515 +107983991 LOC107983991 - +107983992 LOC107983992 - +107983993 UPK3BL2 HGNC:HGNC:53444 +107983994 LOC107983994 - +107983995 LOC107983995 - +107983996 LOC107983996 - +107983997 LOC107983997 - +107983998 LOC107983998 - +107983999 LOC107983999 - +107984000 LOC107984000 - +107984001 LOC107984001 - +107984002 LOC107984002 - +107984003 LOC107984003 - +107984004 LOC107984004 - +107984005 LOC107984005 - +107984006 LOC107984006 - +107984007 LOC107984007 - +107984009 LINC00415 HGNC:HGNC:42748 +107984010 LOC107984010 - +107984011 LOC107984011 - +107984012 LOC107984012 - +107984013 LOC107984013 - +107984014 LOC107984014 - +107984015 LOC107984015 - +107984016 LOC107984016 - +107984017 LOC107984017 - +107984018 LOC107984018 - +107984019 LOC107984019 - +107984020 LOC107984020 - +107984021 LOC107984021 - +107984022 LOC107984022 - +107984023 LOC107984023 - +107984024 LOC107984024 - +107984025 LOC107984025 - +107984026 LOC107984026 - +107984027 LINC02277 HGNC:HGNC:53193 +107984028 LOC107984028 - +107984029 LOC107984029 - +107984030 LOC107984030 - +107984031 LOC107984031 - +107984032 LOC107984032 - +107984033 LOC107984033 - +107984034 LOC107984034 - 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Ensembl:ENSG00000161270 +107985318 LOC107985318 - +107985319 LOC107985319 - +107985320 LOC107985320 - +107985321 LOC107985321 - +107985322 LOC107985322 - +107985323 LOC107985323 - +107985324 LOC107985324 - +107985325 LOC107985325 - +107985326 LOC107985326 - +107985327 LOC107985327 - +107985328 LOC107985328 - +107985329 LOC107985329 - +107985330 LOC107985330 - +107985331 LOC107985331 - +107985332 LOC107985332 - +107985333 LOC107985333 - +107985334 LOC107985334 - +107985335 LOC107985335 - +107985336 LOC107985336 - +107985337 LOC107985337 - +107985338 LOC107985338 - +107985339 LOC107985339 - +107985340 LOC107985340 - +107985341 LOC107985341 - +107985342 LOC107985342 - +107985343 LINC01836 HGNC:HGNC:52652 +107985344 LOC107985344 - +107985345 LOC107985345 - +107985346 LOC107985346 - +107985347 LOC107985347 - +107985348 LOC107985348 - +107985349 LOC107985349 - +107985350 LOC107985350 - +107985351 TRNAK-UUU - +107985352 LOC107985352 - +107985353 ACBD3-AS1 HGNC:HGNC:40701 +107985354 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LOC107985777 - +107985778 LOC107985778 - +107985779 LOC107985779 - +107985780 LOC107985780 - +107985781 FSIP2-AS1 HGNC:HGNC:40978 +107985782 LOC107985782 - +107985783 LOC107985783 - +107985784 LOC107985784 - +107985785 LOC107985785 - +107985786 LOC107985786 - +107985787 LOC107985787 - +107985788 LOC107985788 - +107985789 LOC107985789 - +107985790 LOC107985790 - +107985791 LOC107985791 - +107985792 LOC107985792 - +107985793 LOC107985793 - +107985794 LOC107985794 - +107985795 LOC107985795 - +107985796 LOC107985796 - +107985797 LOC107985797 - +107985798 LOC107985798 - +107985799 LOC107985799 - +107985800 LOC107985800 - +107985801 LOC107985801 - +107985802 LOC107985802 - +107985803 LOC107985803 - +107985804 LOC107985804 - +107985805 LOC107985805 - +107985806 LINC01866 HGNC:HGNC:52685 +107985807 LOC107985807 - +107985808 LOC107985808 - +107985809 LOC107985809 - +107985810 LOC107985810 - +107985811 LOC107985811 - +107985812 LOC107985812 - +107985813 LOC107985813 - +107985814 LOC107985814 - 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BPTFP1 HGNC:HGNC:52869 +109286552 KPNA2P3 HGNC:HGNC:52870 +109286553 ARHGAP27P1-BPTFP1-KPNA2P3 HGNC:HGNC:52873 +109286554 LOC109286554 - +109286555 LOC109286555 - +109286556 LOC109286556 - +109286563 LOC109286563 - +109286564 LOC109286564 - +109286569 LOC109286569 - +109363672 LOC109363672 - +109363676 LOC109363676 - +109396974 LOC109396974 - +109433677 LOC109433677 - +109433679 LOC109433679 - +109461473 LOC109461473 - +109461475 LOC109461475 - +109461476 LOC109461476 - +109461477 LOC109461477 - +109461478 LOC109461478 - +109461479 LOC109461479 - +109461484 LOC109461484 - +109504725 LOC109504725 - +109504726 ERV3-1-ZNF117 - +109504727 LOC109504727 - +109504728 LOC109504728 - +109580095 HBB-LCR MIM:152424 +109580097 LOC109580097 - +109609705 LOC109609705 - +109609706 LOC109609706 - +109610631 LOC109610631 - +109611589 LOC109611589 - +109611591 LOC109611591 - +109611593 LOC109611593 - +109614541 LOC109614541 - +109616958 SNORA50D HGNC:HGNC:50433 +109616959 SNORA80C HGNC:HGNC:50434 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HGNC:HGNC:52246 +109616988 SNORD13I HGNC:HGNC:52248 +109616989 SNORD13C HGNC:HGNC:52252 +109616990 SNORD13D HGNC:HGNC:52253 +109616991 SNORD19C HGNC:HGNC:52224 +109616992 SNORA30B HGNC:HGNC:52200 +109616993 SNORA70H HGNC:HGNC:52214 +109616994 SNORA75B HGNC:HGNC:52220 +109616995 SNORD70B HGNC:HGNC:52233 +109616996 SNORD3I HGNC:HGNC:52242 +109616997 SNORA3C HGNC:HGNC:52203 +109616998 SNORA50B HGNC:HGNC:50432 +109616999 SNORA80D HGNC:HGNC:50435 +109617000 SNORA11F HGNC:HGNC:52189 +109617001 SNORA1B HGNC:HGNC:52193 +109617002 SNORA21B HGNC:HGNC:52195 +109617003 SNORA24B HGNC:HGNC:52198 +109617004 SNORA35B HGNC:HGNC:52202 +109617005 SNORA41B HGNC:HGNC:52206 +109617006 SNORA63B HGNC:HGNC:52209 +109617007 SNORA63E HGNC:HGNC:52212 +109617008 SNORA70I HGNC:HGNC:52215 +109617009 SNORA74C-2 HGNC:HGNC:52218 +109617010 SNORA77B HGNC:HGNC:52221 +109617011 SNORD28B HGNC:HGNC:52225 +109617012 SNORD53B HGNC:HGNC:52229 +109617013 SNORD63B HGNC:HGNC:52230 +109617014 SNORD74B HGNC:HGNC:52234 +109617015 SNORD3E HGNC:HGNC:52238 +109617016 SNORD3H HGNC:HGNC:52241 +109617017 SNORD3K HGNC:HGNC:52244 +109617018 SNORD13H HGNC:HGNC:52247 +109617019 SNORD13B-1 HGNC:HGNC:52250 +109617020 SNORD13E HGNC:HGNC:52254 +109617021 SNORD13B-2 HGNC:HGNC:52251 +109617022 SNORA15B-2 HGNC:HGNC:52192 +109617023 SNORA58B HGNC:HGNC:52208 +109617024 SNORD38C HGNC:HGNC:52227 +109617025 SNORD13J HGNC:HGNC:52249 +109617027 LOC109617027 - +109621227 LOC109621227 - +109623450 SNORD155 HGNC:HGNC:51869 +109623451 SNORD157 HGNC:HGNC:51871 +109623452 SNORD159 HGNC:HGNC:51873 +109623453 SNORD161 HGNC:HGNC:51875 +109623454 SNORD162 HGNC:HGNC:51876 +109623455 SNORD165 HGNC:HGNC:51879 +109623456 SNORD167 HGNC:HGNC:51881 +109623457 SNORD168 HGNC:HGNC:51882 +109623458 SNORD170 HGNC:HGNC:51884 +109623459 SNORA25B HGNC:HGNC:52199 +109623460 SNORD138 HGNC:HGNC:50420|Ensembl:ENSG00000284078|miRBase:MI0015997 +109623461 SNORA113 HGNC:HGNC:51851 +109623462 SNORA116 HGNC:HGNC:51854 +109623463 SNORA117 HGNC:HGNC:51855 +109623464 SNORA119 HGNC:HGNC:51857 +109623465 SNORD147 HGNC:HGNC:51861 +109623466 SNORD148 HGNC:HGNC:51862 +109623467 SNORD150 HGNC:HGNC:51864 +109623468 SNORD151 HGNC:HGNC:51865 +109623469 SNORD175 HGNC:HGNC:51889 +109623470 SNORD158 HGNC:HGNC:51872 +109623471 SNORD172 HGNC:HGNC:51886 +109623472 SNORD145 HGNC:HGNC:51859 +109623473 SNORD152 HGNC:HGNC:51866 +109623474 SNORD154 HGNC:HGNC:51868 +109623475 SNORD156 HGNC:HGNC:51870 +109623476 SNORD160 HGNC:HGNC:51874 +109623477 SNORD163 HGNC:HGNC:51877 +109623478 SNORD166 HGNC:HGNC:51880 +109623479 SNORD169 HGNC:HGNC:51883 +109623480 SNORD173 HGNC:HGNC:51887 +109623481 SNORA112 HGNC:HGNC:51850 +109623482 SNORA115 HGNC:HGNC:51853 +109623483 SNORA118 HGNC:HGNC:51856 +109623484 SNORD146 HGNC:HGNC:51860 +109623485 SNORD149 HGNC:HGNC:51863 +109623486 SNORD153 HGNC:HGNC:51867 +109623487 SNORD164 HGNC:HGNC:51878 +109623488 SNORA114 HGNC:HGNC:51852 +109623489 LOC109623489 - +109623491 LOC109623491 - +109648314 LOC109648314 - +109648316 LOC109648316 - 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HGNC:HGNC:52301 +109729144 MTCYBP40 HGNC:HGNC:52308 +109729145 RPS29P29 HGNC:HGNC:52362 +109729146 POC1B-AS1 HGNC:HGNC:52949 +109729147 LINC02235 HGNC:HGNC:53106 +109729150 MTCYBP35 HGNC:HGNC:52303 +109729151 MTCYBP37 HGNC:HGNC:52305 +109729152 MTCYBP39 HGNC:HGNC:52307 +109729153 MTCYBP42 HGNC:HGNC:52310 +109729154 MTCYBP44 HGNC:HGNC:52312 +109729155 MTCO1P57 HGNC:HGNC:52315 +109729156 MTND4LP32 HGNC:HGNC:52318 +109729157 MTND5P42 HGNC:HGNC:52321 +109729158 RPS29P32 HGNC:HGNC:52365 +109729159 HMGB1P51 HGNC:HGNC:52369 +109729160 ZFHX2-AS1 HGNC:HGNC:52658 +109729161 LNCSRLR HGNC:HGNC:52753 +109729162 LINC02151 HGNC:HGNC:53013 +109729163 CPDP1 HGNC:HGNC:53102 +109729164 LINC02234 HGNC:HGNC:53105 +109729166 LINC02238 HGNC:HGNC:53116 +109729168 NPIPB14P HGNC:HGNC:41990 +109729169 LINC02154 HGNC:HGNC:53015 +109729170 MTND1P37 HGNC:HGNC:52314 +109729172 CD44-AS1 HGNC:HGNC:40133 +109729173 TFAP2A-AS2 MIM:617136|HGNC:HGNC:52289 +109729174 MIR4713HG HGNC:HGNC:53124 +109729177 INO80-AS1 HGNC:HGNC:53138 +109729178 INTS9-AS1 HGNC:HGNC:53139 +109729179 TGFB3-AS1 HGNC:HGNC:53144 +109729180 SNHG26 HGNC:HGNC:53131 +109729181 ZNF710-AS1 HGNC:HGNC:53141 +109729182 DM1-AS HGNC:HGNC:53125 +109729184 SLC12A5-AS1 HGNC:HGNC:53143 +109731405 PDXDC2P HGNC:HGNC:27559 +109819370 MBCS MIM:617352 +109851610 LOC109851610 - +109864269 LOC109864269 - +109864271 RNA45SN4 HGNC:HGNC:53526 +109864272 RNA28SN4 HGNC:HGNC:53527 +109864273 RNA18SN4 HGNC:HGNC:53528 +109864274 RNA5-8SN4 HGNC:HGNC:53529 +109864275 RNA18SP4 HGNC:HGNC:53535 +109864276 RNA5-8SP9 HGNC:HGNC:53537 +109864277 RNA18SP3 HGNC:HGNC:53534 +109864278 RNA5-8SP8 HGNC:HGNC:53536 +109864279 RNA45SN2 HGNC:HGNC:53518 +109864280 RNA18SN2 HGNC:HGNC:53519 +109864281 RNA5-8SN2 HGNC:HGNC:53521 +109864282 RNA28SN2 HGNC:HGNC:53520 +109910379 RNA45SN3 HGNC:HGNC:53522 +109910380 RNA18SN3 HGNC:HGNC:53523 +109910381 RNA5-8SN3 HGNC:HGNC:53525 +109910382 RNA28SN3 HGNC:HGNC:53524 +109910383 RNA18SP5 HGNC:HGNC:53558 +109910384 RNA5-8SP10 HGNC:HGNC:53559 +109951028 A-GAMMA3'E - +109951029 LOC109951029 - +109951030 PKD1P3-NPIPA1 - +110006317 LOC110006317 - +110006318 LOC110006318 - +110006319 LOC110006319 - +110006322 PKD1P5-LOC105376752 - +110006323 PKD1P4-NPIPA8 - +110006325 PPIP5K1P1-CATSPER2 - +110006327 ANKRD20A4-ANKRD20A20P - +110006328 ERVK-32 HGNC:HGNC:53424 +110008579 LOC110008579 - +110008580 LOC110008580 - +110011216 LOC110011216 - +110011217 LOC110011217 - +110013311 LOC110013311 - +110013312 LOC110013312 - +110091768 LOC110091768 - +110091775 C21orf59-TCP10L - +110091776 LOC110091776 - +110091777 LOC110091777 - +110116772 ZNF765-ZNF761 - +110117498 LOC110117498 - +110117499 LOC110117498-PIK3R3 - +110120569 LOC110120569 - +110120570 LOC110120570 - +110120571 LOC110120571 - +110120572 LOC110120572 - +110120573 LOC110120573 - +110120574 LOC110120574 - +110120575 LOC110120575 - +110120576 LOC110120576 - +110120577 LOC110120577 - +110120578 LOC110120578 - +110120579 LOC110120579 - +110120580 LOC110120580 - 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LOC110120620 - +110120621 LOC110120621 - +110120622 LOC110120622 - +110120623 LOC110120623 - +110120624 LOC110120624 - +110120625 LOC110120625 - +110120626 LOC110120626 - +110120627 LOC110120627 - +110120628 LOC110120628 - +110120629 LOC110120629 - +110120630 LOC110120630 - +110120631 LOC110120631 - +110120632 LOC110120632 - +110120633 LOC110120633 - +110120634 LOC110120634 - +110120635 LOC110120635 - +110120636 LOC110120636 - +110120637 LOC110120637 - +110120638 LOC110120638 - +110120640 LOC110120640 - +110120641 LOC110120641 - +110120642 LOC110120642 - +110120643 LOC110120643 - +110120644 LOC110120644 - +110120645 LOC110120645 - +110120646 LOC110120646 - +110120647 LOC110120647 - +110120648 LOC110120648 - +110120649 LOC110120649 - +110120650 LOC110120650 - +110120651 LOC110120651 - +110120652 LOC110120652 - +110120653 LOC110120653 - +110120654 LOC110120654 - +110120655 LOC110120655 - +110120656 LOC110120656 - +110120657 LOC110120657 - +110120658 LOC110120658 - +110120659 LOC110120659 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LOC110120699 - +110120700 LOC110120700 - +110120701 LOC110120701 - +110120702 LOC110120702 - +110120703 LOC110120703 - +110120704 LOC110120704 - +110120705 LOC110120705 - +110120706 LOC110120706 - +110120708 LOC110120708 - +110120709 LOC110120709 - +110120710 LOC110120710 - +110120711 LOC110120711 - +110120712 LOC110120712 - +110120713 LOC110120713 - +110120714 LOC110120714 - +110120715 LOC110120715 - +110120716 LOC110120716 - +110120717 LOC110120717 - +110120718 LOC110120718 - +110120719 LOC110120719 - +110120720 LOC110120720 - +110120721 LOC110120721 - +110120722 LOC110120722 - +110120723 LOC110120723 - +110120724 LOC110120724 - +110120725 LOC110120725 - +110120726 LOC110120726 - +110120727 LOC110120727 - +110120728 LOC110120728 - +110120729 LOC110120729 - +110120730 LOC110120730 - +110120731 LOC110120731 - +110120732 LOC110120732 - +110120733 LOC110120733 - +110120734 LOC110120734 - +110120735 LOC110120735 - +110120736 LOC110120736 - +110120737 LOC110120737 - +110120738 LOC110120738 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- +110354863 ZNF660-ZNF197 - +110366354 LOC110366354 - +110366355 LOC110366355 - +110366357 PACD MIM:612868 +110384692 LOC110384692 - +110386947 LOC110386947 - +110386948 LOC110386948 - +110386949 LOC110386949 - +110386951 LOC110386951 - +110408762 LOC110408762 - +110437700 FLICR HGNC:HGNC:53589 +110440226 CCZ1P - +110467515 LOC110467515 - +110467516 LOC110467516 - +110467517 LOC110467517 - +110467518 RNA5-8SP - +110467520 RNA5-8SP - +110467521 RNA5-8SP - +110467522 RNA5-8SP - +110467523 RNA5-8SP - +110467524 RNA5-8SP - +110467525 RNA28SP - +110467526 RNA28SP - +110467527 RNA28SP - +110467528 RNA28SP - +110467529 RNA28SP - +110467531 RNA28SP - +110467532 RNA18SP - +110467533 RNA18SP - +110467534 RNA18SP - +110467535 RNA18SP - +110467536 RNA18SP - +110467537 RNA18SP - +110467538 RNA18SP - +110485084 LOC110485084 - +110485085 LOC110485085 - +110594336 LOC110594336 - +110594337 LOC110594337 - +110596863 LOC110596863 - +110596865 LOC110596865 - +110596866 LOC110596866 - +110596867 LOC110596867 - +110599562 LOC110599562 - +110599563 LY6G6F-LY6G6D - +110599564 EEF1AKMT4 HGNC:HGNC:53611 +110599565 UC.134 - +110599567 LOC110599567 - +110599568 LOC110599568 - +110599569 LOC110599569 - +110599570 LOC110599570 - +110599571 LOC110599571 - +110599572 LOC110599572 - +110599575 LOC110599575 - +110599576 LOC110599576 - +110599577 LOC110599577 - +110599578 LOC110599578 - +110599579 LOC110599579 - +110599580 LOC110599580 - +110599582 LOC110599582 - +110599583 EEF1AKMT4-ECE2 - +110599585 LOC110599585 - +110599586 LOC110599586 - +6775062 trnT - +6775063 ND6 - +6775064 trnE - +6775065 CYTB - +6775066 ND5 - +6775067 trnL - +6775068 trnS - +6775069 trnH - +6775070 trnR - +6775071 ND4L - +6775072 ND4 - +6775073 COX3 - +6775074 ATP6 - +6775075 trnG - +6775076 ND3 - +6775077 ATP8 - +6775078 trnK - +6775079 COX2 - +6775080 trnS - +6775081 trnD - +6775082 trnY - +6775083 COX1 - +6775084 trnC - +6775085 16S rRNA - +6775086 trnL - +6775087 12S rRNA - +6775088 trnF - +6775089 trnP - +6775090 trnV - +6775091 trnN - +6775092 trnW - +6775093 trnA - +6775094 ND2 - +6775095 trnQ - +6775096 trnM - +6775097 trnI - +6775098 ND1 - +8923184 trnF - +8923185 trnV - +8923186 trnL - +8923187 COX3 - +8923188 ATP6 - +8923189 trnS - +8923190 trnK - +8923191 trnG - +8923192 trnT - +8923193 trnI - +8923194 trnW - +8923195 trnR - +8923196 trnH - +8923197 ND4 - +8923198 ND6 - +8923199 trnE - +8923200 trnC - +8923201 ND4L - +8923202 COX2 - +8923203 trnY - +8923204 trnM - +8923205 CYTB - +8923206 ND3 - +8923207 trnS - +8923208 trnQ - +8923209 ND1 - +8923210 ND5 - +8923211 ATP8 - +8923212 ND2 - +8923213 12S rRNA - +8923214 trnL - +8923215 trnD - +8923216 trnP - +8923217 trnA - +8923218 COX1 - +8923219 16S rRNA - diff --git a/resources/mm_ncbi_genes.tsv b/resources/mm_ncbi_genes.tsv new file mode 100644 index 0000000..7e26f33 --- /dev/null +++ b/resources/mm_ncbi_genes.tsv @@ -0,0 +1,69103 @@ +GeneID Symbol dbXrefs +11287 Pzp MGI:MGI:87854|Ensembl:ENSMUSG00000030359|Vega:OTTMUSG00000022212 +11298 Aanat MGI:MGI:1328365|Ensembl:ENSMUSG00000020804|Vega:OTTMUSG00000003949 +11302 Aatk MGI:MGI:1197518|Ensembl:ENSMUSG00000025375|Vega:OTTMUSG00000004053 +11303 Abca1 MGI:MGI:99607|Ensembl:ENSMUSG00000015243|Vega:OTTMUSG00000007157 +11304 Abca4 MGI:MGI:109424|Ensembl:ENSMUSG00000028125|Vega:OTTMUSG00000029911 +11305 Abca2 MGI:MGI:99606|Ensembl:ENSMUSG00000026944|Vega:OTTMUSG00000012108 +11306 Abcb7 MGI:MGI:109533|Ensembl:ENSMUSG00000031333|Vega:OTTMUSG00000018115 +11307 Abcg1 MGI:MGI:107704|Ensembl:ENSMUSG00000024030|Vega:OTTMUSG00000025573 +11308 Abi1 MGI:MGI:104913|Ensembl:ENSMUSG00000058835|Vega:OTTMUSG00000016621 +11350 Abl1 MGI:MGI:87859|Ensembl:ENSMUSG00000026842|Vega:OTTMUSG00000012077 +11352 Abl2 MGI:MGI:87860|Ensembl:ENSMUSG00000026596|Vega:OTTMUSG00000037114 +11354 Scgb1b27 MGI:MGI:87862|Ensembl:ENSMUSG00000066583|Vega:OTTMUSG00000008372 +11358 ac MGI:MGI:87865 +11363 Acadl MGI:MGI:87866|Ensembl:ENSMUSG00000026003|Vega:OTTMUSG00000026221 +11364 Acadm MGI:MGI:87867|Ensembl:ENSMUSG00000062908|Vega:OTTMUSG00000031346 +11370 Acadvl MGI:MGI:895149|Ensembl:ENSMUSG00000018574|Vega:OTTMUSG00000006027 +11409 Acads MGI:MGI:87868|Ensembl:ENSMUSG00000029545|Vega:OTTMUSG00000014625 +11416 Slc33a1 MGI:MGI:1332247|Ensembl:ENSMUSG00000027822|Vega:OTTMUSG00000026586 +11418 Asic2 MGI:MGI:1100867|Ensembl:ENSMUSG00000020704|Vega:OTTMUSG00000000859 +11419 Asic1 MGI:MGI:1194915|Ensembl:ENSMUSG00000023017 +11421 Ace MGI:MGI:87874|Ensembl:ENSMUSG00000020681|Vega:OTTMUSG00000003113 +11423 Ache MGI:MGI:87876|Ensembl:ENSMUSG00000023328|Vega:OTTMUSG00000021643 +11425 Apoc4 MGI:MGI:87878|Ensembl:ENSMUSG00000074336|Vega:OTTMUSG00000032973 +11426 Macf1 MGI:MGI:108559|Ensembl:ENSMUSG00000028649|Vega:OTTMUSG00000008977 +11428 Aco1 MGI:MGI:87879|Ensembl:ENSMUSG00000028405|Vega:OTTMUSG00000006559 +11429 Aco2 MGI:MGI:87880|Ensembl:ENSMUSG00000022477|Vega:OTTMUSG00000016391 +11430 Acox1 MGI:MGI:1330812|Ensembl:ENSMUSG00000020777|Vega:OTTMUSG00000003754 +11431 Acp1 MGI:MGI:87881|Ensembl:ENSMUSG00000044573 +11432 Acp2 MGI:MGI:87882|Ensembl:ENSMUSG00000002103|Vega:OTTMUSG00000014413 +11433 Acp5 MGI:MGI:87883|Ensembl:ENSMUSG00000001348|Vega:OTTMUSG00000062335 +11434 Acr MGI:MGI:87884|Ensembl:ENSMUSG00000022622 +11435 Chrna1 MGI:MGI:87885|Ensembl:ENSMUSG00000027107|Vega:OTTMUSG00000013434 +11438 Chrna4 MGI:MGI:87888|Ensembl:ENSMUSG00000027577|Vega:OTTMUSG00000016395 +11440 Chrna6 MGI:MGI:106213|Ensembl:ENSMUSG00000031491|Vega:OTTMUSG00000061079 +11441 Chrna7 MGI:MGI:99779|Ensembl:ENSMUSG00000030525|Vega:OTTMUSG00000059577 +11443 Chrnb1 MGI:MGI:87890|Ensembl:ENSMUSG00000041189|Vega:OTTMUSG00000005993 +11444 Chrnb2 MGI:MGI:87891|Ensembl:ENSMUSG00000027950|Vega:OTTMUSG00000052879 +11447 Chrnd MGI:MGI:87893|Ensembl:ENSMUSG00000026251|Vega:OTTMUSG00000048192 +11448 Chrne MGI:MGI:87894|Ensembl:ENSMUSG00000014609|Vega:OTTMUSG00000006059 +11449 Chrng MGI:MGI:87895|Ensembl:ENSMUSG00000026253|Vega:OTTMUSG00000048193 +11450 Adipoq MGI:MGI:106675|Ensembl:ENSMUSG00000022878|Vega:OTTMUSG00000035780 +11451 Acrv1 MGI:MGI:104590|Ensembl:ENSMUSG00000032110|Vega:OTTMUSG00000044745 +11452 act MGI:MGI:87896 +11459 Acta1 MGI:MGI:87902|Ensembl:ENSMUSG00000031972|Vega:OTTMUSG00000062000 +11461 Actb MGI:MGI:87904|Ensembl:ENSMUSG00000029580|Vega:OTTMUSG00000035960 +11464 Actc1 MGI:MGI:87905|Ensembl:ENSMUSG00000068614|Vega:OTTMUSG00000015175 +11465 Actg1 MGI:MGI:87906|Ensembl:ENSMUSG00000062825|Vega:OTTMUSG00000004137 +11468 Actg2 MGI:MGI:104589|Ensembl:ENSMUSG00000059430|Vega:OTTMUSG00000029749 +11470 Actl7a MGI:MGI:1343051|Ensembl:ENSMUSG00000070979|Vega:OTTMUSG00000007270 +11471 Actl7b MGI:MGI:1343053|Ensembl:ENSMUSG00000070980|Vega:OTTMUSG00000007271 +11472 Actn2 MGI:MGI:109192|Ensembl:ENSMUSG00000052374|Vega:OTTMUSG00000017028 +11474 Actn3 MGI:MGI:99678|Ensembl:ENSMUSG00000006457|Vega:OTTMUSG00000016351 +11475 Acta2 MGI:MGI:87909|Ensembl:ENSMUSG00000035783 +11477 Acvr1 MGI:MGI:87911|Ensembl:ENSMUSG00000026836|Vega:OTTMUSG00000012677 +11479 Acvr1b MGI:MGI:1338944|Ensembl:ENSMUSG00000000532|Vega:OTTMUSG00000048171 +11480 Acvr2a MGI:MGI:102806|Ensembl:ENSMUSG00000052155|Vega:OTTMUSG00000012394 +11481 Acvr2b MGI:MGI:87912|Ensembl:ENSMUSG00000061393|Vega:OTTMUSG00000062989 +11482 Acvrl1 MGI:MGI:1338946|Ensembl:ENSMUSG00000000530|Vega:OTTMUSG00000029275 +11484 Aspa MGI:MGI:87914|Ensembl:ENSMUSG00000020774|Vega:OTTMUSG00000006136 +11486 Ada MGI:MGI:87916|Ensembl:ENSMUSG00000017697|Vega:OTTMUSG00000001154 +11487 Adam10 MGI:MGI:109548|Ensembl:ENSMUSG00000054693|Vega:OTTMUSG00000033211 +11488 Adam11 MGI:MGI:1098667|Ensembl:ENSMUSG00000020926|Vega:OTTMUSG00000002992 +11489 Adam12 MGI:MGI:105378|Ensembl:ENSMUSG00000054555|Vega:OTTMUSG00000021264 +11490 Adam15 MGI:MGI:1333882|Ensembl:ENSMUSG00000028041|Vega:OTTMUSG00000022081 +11491 Adam17 MGI:MGI:1096335|Ensembl:ENSMUSG00000052593|Vega:OTTMUSG00000021042 +11492 Adam19 MGI:MGI:105377|Ensembl:ENSMUSG00000011256|Vega:OTTMUSG00000005488 +11495 Adam2 MGI:MGI:1340894|Ensembl:ENSMUSG00000022039 +11496 Adam22 MGI:MGI:1340046|Ensembl:ENSMUSG00000040537|Vega:OTTMUSG00000016341 +11497 Adam3 MGI:MGI:102518|Ensembl:ENSMUSG00000031553|Vega:OTTMUSG00000035967 +11498 Adam4 MGI:MGI:104731|Ensembl:ENSMUSG00000072972|Vega:OTTMUSG00000035309 +11499 Adam5 MGI:MGI:104730|Ensembl:ENSMUSG00000031554|Vega:OTTMUSG00000031764 +11500 Adam7 MGI:MGI:107247|Ensembl:ENSMUSG00000022056|Vega:OTTMUSG00000025841 +11501 Adam8 MGI:MGI:107825|Ensembl:ENSMUSG00000025473|Vega:OTTMUSG00000021266 +11502 Adam9 MGI:MGI:105376|Ensembl:ENSMUSG00000031555|Vega:OTTMUSG00000060065 +11504 Adamts1 MGI:MGI:109249|Ensembl:ENSMUSG00000022893|Vega:OTTMUSG00000019935 +11512 Adcy6 MGI:MGI:87917|Ensembl:ENSMUSG00000022994 +11513 Adcy7 MGI:MGI:102891|Ensembl:ENSMUSG00000031659|Vega:OTTMUSG00000061472 +11514 Adcy8 MGI:MGI:1341110|Ensembl:ENSMUSG00000022376 +11515 Adcy9 MGI:MGI:108450|Ensembl:ENSMUSG00000005580|Vega:OTTMUSG00000027177 +11516 Adcyap1 MGI:MGI:105094|Ensembl:ENSMUSG00000024256 +11517 Adcyap1r1 MGI:MGI:108449|Ensembl:ENSMUSG00000029778|Vega:OTTMUSG00000035961 +11518 Add1 MGI:MGI:87918|Ensembl:ENSMUSG00000029106|Vega:OTTMUSG00000023097 +11519 Add2 MGI:MGI:87919|Ensembl:ENSMUSG00000030000|Vega:OTTMUSG00000056411 +11520 Plin2 MGI:MGI:87920|Ensembl:ENSMUSG00000028494|Vega:OTTMUSG00000007453 +11522 Adh1 MGI:MGI:87921|Ensembl:ENSMUSG00000074207|Vega:OTTMUSG00000034747 +11529 Adh7 MGI:MGI:87926|Ensembl:ENSMUSG00000055301|Vega:OTTMUSG00000052803 +11532 Adh5 MGI:MGI:87929|Ensembl:ENSMUSG00000028138|Vega:OTTMUSG00000029527 +11533 Adh5-ps1 MGI:MGI:106674 +11534 Adk MGI:MGI:87930|Ensembl:ENSMUSG00000039197 +11535 Adm MGI:MGI:108058|Ensembl:ENSMUSG00000030790|Vega:OTTMUSG00000046239 +11536 Gpr182 MGI:MGI:109545|Ensembl:ENSMUSG00000058396|Vega:OTTMUSG00000027657 +11537 Cfd MGI:MGI:87931|Ensembl:ENSMUSG00000061780 +11538 Adnp MGI:MGI:1338758|Ensembl:ENSMUSG00000051149|Vega:OTTMUSG00000016054 +11539 Adora1 MGI:MGI:99401|Ensembl:ENSMUSG00000042429|Vega:OTTMUSG00000049675 +11540 Adora2a MGI:MGI:99402|Ensembl:ENSMUSG00000020178 +11541 Adora2b MGI:MGI:99403|Ensembl:ENSMUSG00000018500|Vega:OTTMUSG00000005854 +11542 Adora3 MGI:MGI:104847|Ensembl:ENSMUSG00000000562|Vega:OTTMUSG00000052379 +11544 Adprh MGI:MGI:1098234|Ensembl:ENSMUSG00000002844 +11545 Parp1 MGI:MGI:1340806|Ensembl:ENSMUSG00000026496|Vega:OTTMUSG00000050450 +11546 Parp2 MGI:MGI:1341112|Ensembl:ENSMUSG00000036023 +11548 Adra1b MGI:MGI:104774|Ensembl:ENSMUSG00000050541|Vega:OTTMUSG00000005462 +11549 Adra1a MGI:MGI:104773|Ensembl:ENSMUSG00000045875|Vega:OTTMUSG00000034681 +11550 Adra1d MGI:MGI:106673|Ensembl:ENSMUSG00000027335|Vega:OTTMUSG00000016190 +11551 Adra2a MGI:MGI:87934|Ensembl:ENSMUSG00000033717 +11552 Adra2b MGI:MGI:87935|Ensembl:ENSMUSG00000058620|Vega:OTTMUSG00000016023 +11553 Adra2c MGI:MGI:87936|Ensembl:ENSMUSG00000045318|Vega:OTTMUSG00000056027 +11554 Adrb1 MGI:MGI:87937|Ensembl:ENSMUSG00000035283 +11555 Adrb2 MGI:MGI:87938|Ensembl:ENSMUSG00000045730 +11556 Adrb3 MGI:MGI:87939|Ensembl:ENSMUSG00000031489|Vega:OTTMUSG00000028657 +11564 Adsl MGI:MGI:103202|Ensembl:ENSMUSG00000022407|Vega:OTTMUSG00000035645 +11565 Adssl1 MGI:MGI:87947|Ensembl:ENSMUSG00000011148 +11566 Adss MGI:MGI:87948|Ensembl:ENSMUSG00000015961|Vega:OTTMUSG00000034836 +11567 Avil MGI:MGI:1333798|Ensembl:ENSMUSG00000025432|Vega:OTTMUSG00000034112 +11568 Aebp1 MGI:MGI:1197012|Ensembl:ENSMUSG00000020473|Vega:OTTMUSG00000005099 +11569 Aebp2 MGI:MGI:1338038|Ensembl:ENSMUSG00000030232|Vega:OTTMUSG00000034195 +11571 Crisp1 MGI:MGI:102553|Ensembl:ENSMUSG00000025431|Vega:OTTMUSG00000037980 +11572 Crisp3 MGI:MGI:102552|Ensembl:ENSMUSG00000025433|Vega:OTTMUSG00000028254 +11576 Afp MGI:MGI:87951|Ensembl:ENSMUSG00000054932|Vega:OTTMUSG00000055486 +11592 ag MGI:MGI:87955 +11593 Aga MGI:MGI:104873|Ensembl:ENSMUSG00000031521|Vega:OTTMUSG00000060612 +11595 Acan MGI:MGI:99602|Ensembl:ENSMUSG00000030607|Vega:OTTMUSG00000058542 +11596 Ager MGI:MGI:893592|Ensembl:ENSMUSG00000015452|Vega:OTTMUSG00000037074 +11600 Angpt1 MGI:MGI:108448|Ensembl:ENSMUSG00000022309 +11601 Angpt2 MGI:MGI:1202890|Ensembl:ENSMUSG00000031465|Vega:OTTMUSG00000036075 +11602 Angpt4 MGI:MGI:1336887|Ensembl:ENSMUSG00000027460|Vega:OTTMUSG00000015844 +11603 Agrn MGI:MGI:87961|Ensembl:ENSMUSG00000041936|Vega:OTTMUSG00000011080 +11604 Agrp MGI:MGI:892013|Ensembl:ENSMUSG00000005705|Vega:OTTMUSG00000050255 +11605 Gla MGI:MGI:1347344|Ensembl:ENSMUSG00000031266|Vega:OTTMUSG00000019384 +11606 Agt MGI:MGI:87963|Ensembl:ENSMUSG00000031980|Vega:OTTMUSG00000061562 +11607 Agtr1a MGI:MGI:87964|Ensembl:ENSMUSG00000049115|Vega:OTTMUSG00000000668 +11608 Agtr1b MGI:MGI:87965|Ensembl:ENSMUSG00000054988|Vega:OTTMUSG00000034694 +11609 Agtr2 MGI:MGI:87966|Ensembl:ENSMUSG00000068122|Vega:OTTMUSG00000017210 +11610 Agtrap MGI:MGI:1339977|Ensembl:ENSMUSG00000029007|Vega:OTTMUSG00000010935 +11611 Agxt MGI:MGI:1329033|Ensembl:ENSMUSG00000026272|Vega:OTTMUSG00000048639 +11614 Nr0b1 MGI:MGI:1352460|Ensembl:ENSMUSG00000025056|Vega:OTTMUSG00000017945 +11615 Gm4737 MGI:MGI:3643647|Ensembl:ENSMUSG00000048087 +11622 Ahr MGI:MGI:105043|Ensembl:ENSMUSG00000019256|Vega:OTTMUSG00000036999 +11624 Ahrr MGI:MGI:1333776|Ensembl:ENSMUSG00000021575|Vega:OTTMUSG00000023058 +11625 Ahsg MGI:MGI:107189|Ensembl:ENSMUSG00000022868 +11628 Aicda MGI:MGI:1342279|Ensembl:ENSMUSG00000040627|Vega:OTTMUSG00000034572 +11629 Aif1 MGI:MGI:1343098|Ensembl:ENSMUSG00000024397|Vega:OTTMUSG00000037184 +11630 Crybg1 MGI:MGI:109544|Ensembl:ENSMUSG00000019866|Vega:OTTMUSG00000055246 +11632 Aip MGI:MGI:109622|Ensembl:ENSMUSG00000024847|Vega:OTTMUSG00000026281 +11634 Aire MGI:MGI:1338803|Ensembl:ENSMUSG00000000731|Vega:OTTMUSG00000034126 +11636 Ak1 MGI:MGI:87977|Ensembl:ENSMUSG00000026817|Vega:OTTMUSG00000011984 +11637 Ak2 MGI:MGI:87978|Ensembl:ENSMUSG00000028792|Vega:OTTMUSG00000009623 +11639 Ak4 MGI:MGI:87979|Ensembl:ENSMUSG00000028527|Vega:OTTMUSG00000008456 +11640 Akap1 MGI:MGI:104729|Ensembl:ENSMUSG00000018428|Vega:OTTMUSG00000001272 +11641 Akap2 MGI:MGI:1306795|Ensembl:ENSMUSG00000038729|Vega:OTTMUSG00000032475 +11642 Akap3 MGI:MGI:1341149|Ensembl:ENSMUSG00000030344|Vega:OTTMUSG00000056337 +11643 Akap4 MGI:MGI:102794|Ensembl:ENSMUSG00000050089|Vega:OTTMUSG00000016457 +11647 Alpl MGI:MGI:87983|Ensembl:ENSMUSG00000028766|Vega:OTTMUSG00000009805 +11648 Akp3 MGI:MGI:87984|Ensembl:ENSMUSG00000036500|Vega:OTTMUSG00000048155 +11650 Alppl2 MGI:MGI:108009|Ensembl:ENSMUSG00000026246|Vega:OTTMUSG00000048152 +11651 Akt1 MGI:MGI:87986|Ensembl:ENSMUSG00000001729|Vega:OTTMUSG00000020941 +11652 Akt2 MGI:MGI:104874|Ensembl:ENSMUSG00000004056|Vega:OTTMUSG00000016504 +11655 Alas1 MGI:MGI:87989|Ensembl:ENSMUSG00000032786|Vega:OTTMUSG00000033383 +11656 Alas2 MGI:MGI:87990|Ensembl:ENSMUSG00000025270|Vega:OTTMUSG00000019150 +11657 Alb MGI:MGI:87991|Ensembl:ENSMUSG00000029368|Vega:OTTMUSG00000055485 +11658 Alcam MGI:MGI:1313266|Ensembl:ENSMUSG00000022636|Vega:OTTMUSG00000036124 +11666 Abcd1 MGI:MGI:1349215|Ensembl:ENSMUSG00000031378|Vega:OTTMUSG00000017700 +11668 Aldh1a1 MGI:MGI:1353450|Ensembl:ENSMUSG00000053279|Vega:OTTMUSG00000021238 +11669 Aldh2 MGI:MGI:99600|Ensembl:ENSMUSG00000029455|Vega:OTTMUSG00000023440 +11670 Aldh3a1 MGI:MGI:1353451|Ensembl:ENSMUSG00000019102|Vega:OTTMUSG00000005823 +11671 Aldh3a2 MGI:MGI:1353452|Ensembl:ENSMUSG00000010025|Vega:OTTMUSG00000005829 +11674 Aldoa MGI:MGI:87994|Ensembl:ENSMUSG00000030695|Vega:OTTMUSG00000025167 +11676 Aldoc MGI:MGI:101863|Ensembl:ENSMUSG00000017390|Vega:OTTMUSG00000000108 +11677 Akr1b3 MGI:MGI:1353494|Ensembl:ENSMUSG00000001642|Vega:OTTMUSG00000014776 +11682 Alk MGI:MGI:103305|Ensembl:ENSMUSG00000055471 +11684 Alox12 MGI:MGI:87998|Ensembl:ENSMUSG00000000320|Vega:OTTMUSG00000006035 +11685 Alox12e MGI:MGI:1274790|Ensembl:ENSMUSG00000018907|Vega:OTTMUSG00000006041 +11686 Alox12b MGI:MGI:1274782|Ensembl:ENSMUSG00000032807|Vega:OTTMUSG00000005964 +11687 Alox15 MGI:MGI:87997|Ensembl:ENSMUSG00000018924|Vega:OTTMUSG00000006044 +11688 Alox8 MGI:MGI:1098228|Ensembl:ENSMUSG00000020891|Vega:OTTMUSG00000005969 +11689 Alox5 MGI:MGI:87999|Ensembl:ENSMUSG00000025701|Vega:OTTMUSG00000036516 +11690 Alox5ap MGI:MGI:107505|Ensembl:ENSMUSG00000060063|Vega:OTTMUSG00000028828 +11691 alp MGI:MGI:88000 +11692 Gfer MGI:MGI:107757|Ensembl:ENSMUSG00000040888 +11694 Alx3 MGI:MGI:1277097|Ensembl:ENSMUSG00000014603|Vega:OTTMUSG00000035928 +11695 Alx4 MGI:MGI:108359|Ensembl:ENSMUSG00000040310|Vega:OTTMUSG00000014563 +11697 am MGI:MGI:88001 +11698 Ambn MGI:MGI:104655|Ensembl:ENSMUSG00000029288|Vega:OTTMUSG00000055387 +11699 Ambp MGI:MGI:88002|Ensembl:ENSMUSG00000028356|Vega:OTTMUSG00000009032 +11700 amd MGI:MGI:88003 +11701 Amd-ps1 MGI:MGI:1310005 +11702 Amd1 MGI:MGI:88004|Ensembl:ENSMUSG00000075232|Vega:OTTMUSG00000063451 +11704 Amelx MGI:MGI:88005|Ensembl:ENSMUSG00000031354|Vega:OTTMUSG00000019595 +11705 Amh MGI:MGI:88006|Ensembl:ENSMUSG00000035262 +11717 Ampd3 MGI:MGI:1096344|Ensembl:ENSMUSG00000005686|Vega:OTTMUSG00000023504 +11720 Mat1a MGI:MGI:88017|Ensembl:ENSMUSG00000037798 +11722 Amy1 MGI:MGI:88019|Ensembl:ENSMUSG00000074264|Vega:OTTMUSG00000022392 +11727 Ang MGI:MGI:88022|Ensembl:ENSMUSG00000072115 +11728 Ang-ps1 MGI:MGI:104986 +11730 Ang3 MGI:MGI:1201793 +11731 Ang2 MGI:MGI:104984|Ensembl:ENSMUSG00000047894 +11732 Ank MGI:MGI:3045421|Ensembl:ENSMUSG00000022265|Vega:OTTMUSG00000026300 +11733 Ank1 MGI:MGI:88024|Ensembl:ENSMUSG00000031543|Vega:OTTMUSG00000026381 +11735 Ank3 MGI:MGI:88026|Ensembl:ENSMUSG00000069601|Vega:OTTMUSG00000043361 +11736 Ankfy1 MGI:MGI:1337008|Ensembl:ENSMUSG00000020790|Vega:OTTMUSG00000006114 +11737 Anp32a MGI:MGI:108447|Ensembl:ENSMUSG00000032249|Vega:OTTMUSG00000033323 +11739 Slc25a4 MGI:MGI:1353495|Ensembl:ENSMUSG00000031633|Vega:OTTMUSG00000016487 +11740 Slc25a5 MGI:MGI:1353496|Ensembl:ENSMUSG00000016319|Vega:OTTMUSG00000016520 +11743 anx MGI:MGI:88029 +11744 Anxa11 MGI:MGI:108481|Ensembl:ENSMUSG00000021866|Vega:OTTMUSG00000019768 +11745 Anxa3 MGI:MGI:1201378|Ensembl:ENSMUSG00000029484|Vega:OTTMUSG00000053295 +11746 Anxa4 MGI:MGI:88030|Ensembl:ENSMUSG00000029994|Vega:OTTMUSG00000022166 +11747 Anxa5 MGI:MGI:106008|Ensembl:ENSMUSG00000027712|Vega:OTTMUSG00000020273 +11749 Anxa6 MGI:MGI:88255|Ensembl:ENSMUSG00000018340|Vega:OTTMUSG00000006325 +11750 Anxa7 MGI:MGI:88031|Ensembl:ENSMUSG00000021814 +11752 Anxa8 MGI:MGI:1201374|Ensembl:ENSMUSG00000021950|Vega:OTTMUSG00000027916 +11753 ao MGI:MGI:88033 +11754 Aoc3 MGI:MGI:1306797|Ensembl:ENSMUSG00000019326|Vega:OTTMUSG00000002793 +11757 Prdx3 MGI:MGI:88034|Ensembl:ENSMUSG00000024997|Vega:OTTMUSG00000021212 +11758 Prdx6 MGI:MGI:894320|Ensembl:ENSMUSG00000026701|Vega:OTTMUSG00000016463 +11761 Aox1 MGI:MGI:88035|Ensembl:ENSMUSG00000063558|Vega:OTTMUSG00000029784 +11763 ap MGI:MGI:88037 +11764 Ap1b1 MGI:MGI:1096368|Ensembl:ENSMUSG00000009090|Vega:OTTMUSG00000005076 +11765 Ap1g1 MGI:MGI:101919|Ensembl:ENSMUSG00000031731|Vega:OTTMUSG00000037661 +11766 Ap1g2 MGI:MGI:1328307|Ensembl:ENSMUSG00000040701|Vega:OTTMUSG00000027952 +11767 Ap1m1 MGI:MGI:102776|Ensembl:ENSMUSG00000003033|Vega:OTTMUSG00000022231 +11768 Ap1m2 MGI:MGI:1336974|Ensembl:ENSMUSG00000003309|Vega:OTTMUSG00000063271 +11769 Ap1s1 MGI:MGI:1098244|Ensembl:ENSMUSG00000004849|Vega:OTTMUSG00000023414 +11770 Fabp4 MGI:MGI:88038|Ensembl:ENSMUSG00000062515|Vega:OTTMUSG00000051458 +11771 Ap2a1 MGI:MGI:101921|Ensembl:ENSMUSG00000060279|Vega:OTTMUSG00000035384 +11772 Ap2a2 MGI:MGI:101920|Ensembl:ENSMUSG00000002957|Vega:OTTMUSG00000055665 +11773 Ap2m1 MGI:MGI:1298405|Ensembl:ENSMUSG00000022841|Vega:OTTMUSG00000025969 +11774 Ap3b1 MGI:MGI:1333879|Ensembl:ENSMUSG00000021686 +11775 Ap3b2 MGI:MGI:1100869|Ensembl:ENSMUSG00000062444|Vega:OTTMUSG00000031672 +11776 Ap3d1 MGI:MGI:107734|Ensembl:ENSMUSG00000020198 +11777 Ap3s1 MGI:MGI:1337062|Ensembl:ENSMUSG00000024480 +11778 Ap3s2 MGI:MGI:1337060|Ensembl:ENSMUSG00000063801|Vega:OTTMUSG00000058597 +11781 Ap4m1 MGI:MGI:1337063|Ensembl:ENSMUSG00000019518|Vega:OTTMUSG00000022671 +11782 Ap4s1 MGI:MGI:1337065|Ensembl:ENSMUSG00000020955 +11783 Apaf1 MGI:MGI:1306796|Ensembl:ENSMUSG00000019979|Vega:OTTMUSG00000027822 +11784 Apba2 MGI:MGI:1261791|Ensembl:ENSMUSG00000030519|Vega:OTTMUSG00000023522 +11785 Apbb1 MGI:MGI:107765|Ensembl:ENSMUSG00000037032|Vega:OTTMUSG00000048248 +11787 Apbb2 MGI:MGI:108405|Ensembl:ENSMUSG00000029207|Vega:OTTMUSG00000033024 +11789 Apc MGI:MGI:88039|Ensembl:ENSMUSG00000005871|Vega:OTTMUSG00000035932 +11790 Speg MGI:MGI:109282|Ensembl:ENSMUSG00000026207|Vega:OTTMUSG00000019414 +11792 Apex1 MGI:MGI:88042|Ensembl:ENSMUSG00000035960|Vega:OTTMUSG00000019767 +11793 Atg5 MGI:MGI:1277186|Ensembl:ENSMUSG00000038160|Vega:OTTMUSG00000063668 +11796 Birc3 MGI:MGI:1197007|Ensembl:ENSMUSG00000032000|Vega:OTTMUSG00000020585 +11797 Birc2 MGI:MGI:1197009|Ensembl:ENSMUSG00000057367|Vega:OTTMUSG00000047468 +11798 Xiap MGI:MGI:107572|Ensembl:ENSMUSG00000025860|Vega:OTTMUSG00000017444 +11799 Birc5 MGI:MGI:1203517|Ensembl:ENSMUSG00000017716|Vega:OTTMUSG00000003737 +11800 Api5 MGI:MGI:1888993|Ensembl:ENSMUSG00000027193|Vega:OTTMUSG00000014443 +11801 Cd5l MGI:MGI:1334419|Ensembl:ENSMUSG00000015854|Vega:OTTMUSG00000051776 +11803 Aplp1 MGI:MGI:88046|Ensembl:ENSMUSG00000006651|Vega:OTTMUSG00000059360 +11804 Aplp2 MGI:MGI:88047|Ensembl:ENSMUSG00000031996|Vega:OTTMUSG00000062829 +11806 Apoa1 MGI:MGI:88049|Ensembl:ENSMUSG00000032083|Vega:OTTMUSG00000028707 +11807 Apoa2 MGI:MGI:88050|Ensembl:ENSMUSG00000005681|Vega:OTTMUSG00000021666 +11808 Apoa4 MGI:MGI:88051|Ensembl:ENSMUSG00000032080|Vega:OTTMUSG00000028705 +11810 Apobec1 MGI:MGI:103298|Ensembl:ENSMUSG00000040613|Vega:OTTMUSG00000024356 +11811 Apobec2 MGI:MGI:1343178|Ensembl:ENSMUSG00000040694 +11812 Apoc1 MGI:MGI:88053|Ensembl:ENSMUSG00000040564|Vega:OTTMUSG00000059277 +11813 Apoc2 MGI:MGI:88054|Ensembl:ENSMUSG00000002992|Vega:OTTMUSG00000032974 +11814 Apoc3 MGI:MGI:88055|Ensembl:ENSMUSG00000032081|Vega:OTTMUSG00000028703 +11815 Apod MGI:MGI:88056|Ensembl:ENSMUSG00000022548|Vega:OTTMUSG00000025876 +11816 Apoe MGI:MGI:88057|Ensembl:ENSMUSG00000002985|Vega:OTTMUSG00000038239 +11818 Apoh MGI:MGI:88058|Ensembl:ENSMUSG00000000049|Vega:OTTMUSG00000003129 +11819 Nr2f2 MGI:MGI:1352452|Ensembl:ENSMUSG00000030551|Vega:OTTMUSG00000023060 +11820 App MGI:MGI:88059|Ensembl:ENSMUSG00000022892 +11821 Aprt MGI:MGI:88061|Ensembl:ENSMUSG00000006589|Vega:OTTMUSG00000061857 +11826 Aqp1 MGI:MGI:103201|Ensembl:ENSMUSG00000004655|Vega:OTTMUSG00000026098 +11827 Aqp2 MGI:MGI:1096865|Ensembl:ENSMUSG00000023013 +11828 Aqp3 MGI:MGI:1333777|Ensembl:ENSMUSG00000028435|Vega:OTTMUSG00000006621 +11829 Aqp4 MGI:MGI:107387|Ensembl:ENSMUSG00000024411 +11830 Aqp5 MGI:MGI:106215|Ensembl:ENSMUSG00000044217 +11831 Aqp6 MGI:MGI:1341204|Ensembl:ENSMUSG00000043144 +11832 Aqp7 MGI:MGI:1314647|Ensembl:ENSMUSG00000028427|Vega:OTTMUSG00000006623 +11833 Aqp8 MGI:MGI:1195271|Ensembl:ENSMUSG00000030762|Vega:OTTMUSG00000058146 +11834 Aqr MGI:MGI:1276102|Ensembl:ENSMUSG00000040383|Vega:OTTMUSG00000015215 +11835 Ar MGI:MGI:88064|Ensembl:ENSMUSG00000046532|Vega:OTTMUSG00000018072 +11836 Araf MGI:MGI:88065|Ensembl:ENSMUSG00000001127|Vega:OTTMUSG00000017167 +11837 Rplp0 MGI:MGI:1927636|Ensembl:ENSMUSG00000067274|Vega:OTTMUSG00000014700 +11838 Arc MGI:MGI:88067|Ensembl:ENSMUSG00000022602|Vega:OTTMUSG00000016386 +11839 Areg MGI:MGI:88068|Ensembl:ENSMUSG00000029378|Vega:OTTMUSG00000055520 +11840 Arf1 MGI:MGI:99431|Ensembl:ENSMUSG00000048076|Vega:OTTMUSG00000006340 +11841 Arf2 MGI:MGI:99595|Ensembl:ENSMUSG00000062421|Vega:OTTMUSG00000003146 +11842 Arf3 MGI:MGI:99432|Ensembl:ENSMUSG00000051853|Vega:OTTMUSG00000017016 +11843 Arf4 MGI:MGI:99433|Ensembl:ENSMUSG00000021877|Vega:OTTMUSG00000035433 +11844 Arf5 MGI:MGI:99434|Ensembl:ENSMUSG00000020440|Vega:OTTMUSG00000021282 +11845 Arf6 MGI:MGI:99435|Ensembl:ENSMUSG00000044147 +11846 Arg1 MGI:MGI:88070|Ensembl:ENSMUSG00000019987 +11847 Arg2 MGI:MGI:1330806|Ensembl:ENSMUSG00000021125|Vega:OTTMUSG00000033846 +11848 Rhoa MGI:MGI:1096342|Ensembl:ENSMUSG00000007815|Vega:OTTMUSG00000050752 +11849 Rhoay-ps1 MGI:MGI:1314639 +11850 Rhoay-ps2 MGI:MGI:1314636 +11851 Rhoay-ps3 MGI:MGI:1314637 +11852 Rhob MGI:MGI:107949|Ensembl:ENSMUSG00000054364 +11853 Rhoc MGI:MGI:106028|Ensembl:ENSMUSG00000002233|Vega:OTTMUSG00000022218 +11854 Rhod MGI:MGI:108446|Ensembl:ENSMUSG00000041845|Vega:OTTMUSG00000028325 +11855 Arhgap5 MGI:MGI:1332637|Ensembl:ENSMUSG00000035133 +11856 Arhgap6 MGI:MGI:1196332|Ensembl:ENSMUSG00000031355|Vega:OTTMUSG00000019560 +11857 Arhgdib MGI:MGI:101940|Ensembl:ENSMUSG00000030220|Vega:OTTMUSG00000023287 +11858 Rnd2 MGI:MGI:1338755|Ensembl:ENSMUSG00000001313|Vega:OTTMUSG00000002875 +11859 Phox2a MGI:MGI:106633|Ensembl:ENSMUSG00000007946|Vega:OTTMUSG00000037719 +11861 Arl4a MGI:MGI:99437|Ensembl:ENSMUSG00000047446|Vega:OTTMUSG00000032944 +11863 Arnt MGI:MGI:88071|Ensembl:ENSMUSG00000015522|Vega:OTTMUSG00000016472 +11864 Arnt2 MGI:MGI:107188|Ensembl:ENSMUSG00000015709|Vega:OTTMUSG00000059598 +11865 Arntl MGI:MGI:1096381|Ensembl:ENSMUSG00000055116|Vega:OTTMUSG00000060257 +11867 Arpc1b MGI:MGI:1343142|Ensembl:ENSMUSG00000029622|Vega:OTTMUSG00000022984 +11870 Art1 MGI:MGI:107511|Ensembl:ENSMUSG00000030996|Vega:OTTMUSG00000061185 +11871 Art2a-ps MGI:MGI:107546|Ensembl:ENSMUSG00000092517|Vega:OTTMUSG00000033439 +11872 Art2b MGI:MGI:107545|Ensembl:ENSMUSG00000030651|Vega:OTTMUSG00000033440 +11875 Art5 MGI:MGI:107948|Ensembl:ENSMUSG00000070424|Vega:OTTMUSG00000022734 +11876 Artn MGI:MGI:1333791|Ensembl:ENSMUSG00000028539|Vega:OTTMUSG00000008658 +11877 Arvcf MGI:MGI:109620|Ensembl:ENSMUSG00000000325|Vega:OTTMUSG00000026041 +11878 Arx MGI:MGI:1097716|Ensembl:ENSMUSG00000035277|Vega:OTTMUSG00000017972 +11881 Arsb MGI:MGI:88075|Ensembl:ENSMUSG00000042082 +11883 Arsa MGI:MGI:88077|Ensembl:ENSMUSG00000022620|Vega:OTTMUSG00000035225 +11885 asa MGI:MGI:88078 +11886 Asah1 MGI:MGI:1277124|Ensembl:ENSMUSG00000031591|Vega:OTTMUSG00000022574 +11889 Asgr1 MGI:MGI:88081|Ensembl:ENSMUSG00000020884|Vega:OTTMUSG00000006017 +11890 Asgr2 MGI:MGI:88082|Ensembl:ENSMUSG00000040963|Vega:OTTMUSG00000006018 +11891 Rab27a MGI:MGI:1861441|Ensembl:ENSMUSG00000032202|Vega:OTTMUSG00000044792 +11893 Asp1 MGI:MGI:88085 +11894 Asp2 MGI:MGI:88086 +11895 Asp3 MGI:MGI:88087 +11898 Ass1 MGI:MGI:88090|Ensembl:ENSMUSG00000076441|Vega:OTTMUSG00000012079 +11899 Astn1 MGI:MGI:1098567|Ensembl:ENSMUSG00000026587|Vega:OTTMUSG00000050031 +11904 at MGI:MGI:88094 +11905 Serpinc1 MGI:MGI:88095|Ensembl:ENSMUSG00000026715|Vega:OTTMUSG00000050830 +11906 Zfhx3 MGI:MGI:99948|Ensembl:ENSMUSG00000038872|Vega:OTTMUSG00000041077 +11907 Ate1 MGI:MGI:1333870|Ensembl:ENSMUSG00000030850|Vega:OTTMUSG00000059393 +11908 Atf1 MGI:MGI:1298366|Ensembl:ENSMUSG00000023027|Vega:OTTMUSG00000036768 +11909 Atf2 MGI:MGI:109349|Ensembl:ENSMUSG00000027104|Vega:OTTMUSG00000013179 +11910 Atf3 MGI:MGI:109384|Ensembl:ENSMUSG00000026628|Vega:OTTMUSG00000021405 +11911 Atf4 MGI:MGI:88096|Ensembl:ENSMUSG00000042406 +11920 Atm MGI:MGI:107202|Ensembl:ENSMUSG00000034218|Vega:OTTMUSG00000031707 +11921 Atoh1 MGI:MGI:104654|Ensembl:ENSMUSG00000073043|Vega:OTTMUSG00000057064 +11922 Neurod6 MGI:MGI:106593|Ensembl:ENSMUSG00000037984|Vega:OTTMUSG00000057889 +11923 Neurod4 MGI:MGI:108055|Ensembl:ENSMUSG00000048015 +11924 Neurog2 MGI:MGI:109619|Ensembl:ENSMUSG00000027967|Vega:OTTMUSG00000022648 +11925 Neurog3 MGI:MGI:893591|Ensembl:ENSMUSG00000044312 +11927 Atox1 MGI:MGI:1333855|Ensembl:ENSMUSG00000018585|Vega:OTTMUSG00000005691 +11928 Atp1a1 MGI:MGI:88105|Ensembl:ENSMUSG00000033161|Vega:OTTMUSG00000016447 +11931 Atp1b1 MGI:MGI:88108|Ensembl:ENSMUSG00000026576|Vega:OTTMUSG00000049860 +11932 Atp1b2 MGI:MGI:88109|Ensembl:ENSMUSG00000041329|Vega:OTTMUSG00000005985 +11933 Atp1b3 MGI:MGI:107788|Ensembl:ENSMUSG00000032412|Vega:OTTMUSG00000047571 +11936 Fxyd2 MGI:MGI:1195260|Ensembl:ENSMUSG00000059412|Vega:OTTMUSG00000063508 +11937 Atp2a1 MGI:MGI:105058|Ensembl:ENSMUSG00000030730|Vega:OTTMUSG00000025329 +11938 Atp2a2 MGI:MGI:88110|Ensembl:ENSMUSG00000029467|Vega:OTTMUSG00000054516 +11941 Atp2b2 MGI:MGI:105368|Ensembl:ENSMUSG00000030302|Vega:OTTMUSG00000018967 +11944 Atp4a MGI:MGI:88113|Ensembl:ENSMUSG00000005553|Vega:OTTMUSG00000036851 +11945 Atp4b MGI:MGI:88114|Ensembl:ENSMUSG00000031449|Vega:OTTMUSG00000060904 +11946 Atp5a1 MGI:MGI:88115|Ensembl:ENSMUSG00000025428|Vega:OTTMUSG00000017510 +11947 Atp5b MGI:MGI:107801|Ensembl:ENSMUSG00000025393|Vega:OTTMUSG00000023688 +11949 Atp5c1 MGI:MGI:1261437|Ensembl:ENSMUSG00000025781|Vega:OTTMUSG00000011013 +11950 Atp5f1 MGI:MGI:1100495|Ensembl:ENSMUSG00000000563|Vega:OTTMUSG00000027098 +11951 Atp5g1 MGI:MGI:107653|Ensembl:ENSMUSG00000006057|Vega:OTTMUSG00000006275 +11957 Atp5j MGI:MGI:107777|Ensembl:ENSMUSG00000022890|Vega:OTTMUSG00000025153 +11958 Atp5k MGI:MGI:106636|Ensembl:ENSMUSG00000050856|Vega:OTTMUSG00000028932 +11964 Atp6v1a MGI:MGI:1201780|Ensembl:ENSMUSG00000052459|Vega:OTTMUSG00000023485 +11966 Atp6v1b2 MGI:MGI:109618|Ensembl:ENSMUSG00000006273|Vega:OTTMUSG00000025651 +11972 Atp6v0d1 MGI:MGI:1201778|Ensembl:ENSMUSG00000013160|Vega:OTTMUSG00000032456 +11973 Atp6v1e1 MGI:MGI:894326|Ensembl:ENSMUSG00000019210|Vega:OTTMUSG00000056828 +11974 Atp6v0e MGI:MGI:1328318|Ensembl:ENSMUSG00000015575 +11975 Atp6v0a1 MGI:MGI:103286|Ensembl:ENSMUSG00000019302|Vega:OTTMUSG00000002124 +11977 Atp7a MGI:MGI:99400|Ensembl:ENSMUSG00000033792|Vega:OTTMUSG00000018274 +11979 Atp7b MGI:MGI:103297|Ensembl:ENSMUSG00000006567|Vega:OTTMUSG00000020833 +11980 Atp8a1 MGI:MGI:1330848|Ensembl:ENSMUSG00000037685|Vega:OTTMUSG00000022523 +11981 Atp9a MGI:MGI:1330826|Ensembl:ENSMUSG00000027546|Vega:OTTMUSG00000016114 +11982 Atp10a MGI:MGI:1330809|Ensembl:ENSMUSG00000025324|Vega:OTTMUSG00000058914 +11983 Atpif1 MGI:MGI:1196457|Ensembl:ENSMUSG00000054428|Vega:OTTMUSG00000009786 +11984 Atp6v0c MGI:MGI:88116|Ensembl:ENSMUSG00000024121|Vega:OTTMUSG00000023843 +11987 Slc7a1 MGI:MGI:88117|Ensembl:ENSMUSG00000041313|Vega:OTTMUSG00000025707 +11988 Slc7a2 MGI:MGI:99828|Ensembl:ENSMUSG00000031596|Vega:OTTMUSG00000061152 +11989 Slc7a3 MGI:MGI:1100521|Ensembl:ENSMUSG00000031297|Vega:OTTMUSG00000018298 +11990 Atrn MGI:MGI:1341628|Ensembl:ENSMUSG00000027312|Vega:OTTMUSG00000015539 +11991 Hnrnpd MGI:MGI:101947|Ensembl:ENSMUSG00000000568|Vega:OTTMUSG00000036763 +11992 Auh MGI:MGI:1338011|Ensembl:ENSMUSG00000021460|Vega:OTTMUSG00000026355 +11993 Aup1 MGI:MGI:107789|Ensembl:ENSMUSG00000068328|Vega:OTTMUSG00000057842 +11994 Pcdh15 MGI:MGI:1891428|Ensembl:ENSMUSG00000052613|Vega:OTTMUSG00000021142 +11997 Akr1b7 MGI:MGI:101918|Ensembl:ENSMUSG00000052131|Vega:OTTMUSG00000014785 +11998 Avp MGI:MGI:88121|Ensembl:ENSMUSG00000037727|Vega:OTTMUSG00000015526 +12000 Avpr2 MGI:MGI:88123|Ensembl:ENSMUSG00000031390|Vega:OTTMUSG00000017671 +12001 awg MGI:MGI:1203498 +12005 Axin1 MGI:MGI:1096327|Ensembl:ENSMUSG00000024182|Vega:OTTMUSG00000026498 +12006 Axin2 MGI:MGI:1270862|Ensembl:ENSMUSG00000000142|Vega:OTTMUSG00000003199 +12007 Azgp1 MGI:MGI:103163|Ensembl:ENSMUSG00000037053|Vega:OTTMUSG00000054656 +12009 Cep131 MGI:MGI:107440|Ensembl:ENSMUSG00000039781|Vega:OTTMUSG00000004097 +12010 B2m MGI:MGI:88127|Ensembl:ENSMUSG00000060802|Vega:OTTMUSG00000015534 +12011 ba MGI:MGI:88128 +12012 Baat MGI:MGI:106642|Ensembl:ENSMUSG00000039653|Vega:OTTMUSG00000008315 +12013 Bach1 MGI:MGI:894680|Ensembl:ENSMUSG00000025612|Vega:OTTMUSG00000026479 +12014 Bach2 MGI:MGI:894679|Ensembl:ENSMUSG00000040270|Vega:OTTMUSG00000004927 +12015 Bad MGI:MGI:1096330|Ensembl:ENSMUSG00000024959|Vega:OTTMUSG00000016347 +12016 baf MGI:MGI:99827 +12017 Bag1 MGI:MGI:108047|Ensembl:ENSMUSG00000028416|Vega:OTTMUSG00000006605 +12018 Bak1 MGI:MGI:1097161|Ensembl:ENSMUSG00000057789|Vega:OTTMUSG00000030987 +12020 Nkx3-2 MGI:MGI:108015|Ensembl:ENSMUSG00000049691|Vega:OTTMUSG00000036567 +12021 Bard1 MGI:MGI:1328361|Ensembl:ENSMUSG00000026196|Vega:OTTMUSG00000030938 +12022 Barx1 MGI:MGI:103124|Ensembl:ENSMUSG00000021381|Vega:OTTMUSG00000037223 +12023 Barx2 MGI:MGI:109617|Ensembl:ENSMUSG00000032033|Vega:OTTMUSG00000037222 +12028 Bax MGI:MGI:99702|Ensembl:ENSMUSG00000003873|Vega:OTTMUSG00000059409 +12029 Bcl6b MGI:MGI:1278332|Ensembl:ENSMUSG00000000317|Vega:OTTMUSG00000006040 +12031 Bc1-ps1 MGI:MGI:5052079 +12032 Bcan MGI:MGI:1096385|Ensembl:ENSMUSG00000004892|Vega:OTTMUSG00000051892 +12033 Bcap29 MGI:MGI:101917|Ensembl:ENSMUSG00000020650 +12034 Phb2 MGI:MGI:102520|Ensembl:ENSMUSG00000004264|Vega:OTTMUSG00000020695 +12035 Bcat1 MGI:MGI:104861|Ensembl:ENSMUSG00000030268|Vega:OTTMUSG00000025302 +12036 Bcat2 MGI:MGI:1276534|Ensembl:ENSMUSG00000030826|Vega:OTTMUSG00000030313 +12038 Bche MGI:MGI:894278|Ensembl:ENSMUSG00000027792|Vega:OTTMUSG00000026601 +12039 Bckdha MGI:MGI:107701|Ensembl:ENSMUSG00000060376|Vega:OTTMUSG00000058394 +12040 Bckdhb MGI:MGI:88137|Ensembl:ENSMUSG00000032263|Vega:OTTMUSG00000044979 +12041 Bckdk MGI:MGI:1276121|Ensembl:ENSMUSG00000030802|Vega:OTTMUSG00000025391 +12042 Bcl10 MGI:MGI:1337994|Ensembl:ENSMUSG00000028191|Vega:OTTMUSG00000055197 +12043 Bcl2 MGI:MGI:88138|Ensembl:ENSMUSG00000057329|Vega:OTTMUSG00000022128 +12044 Bcl2a1a MGI:MGI:102687|Ensembl:ENSMUSG00000102037|Vega:OTTMUSG00000045614 +12045 Bcl2a1b MGI:MGI:1278326|Ensembl:ENSMUSG00000089929|Vega:OTTMUSG00000031931 +12046 Bcl2a1c MGI:MGI:1278327|Ensembl:ENSMUSG00000053820|Vega:OTTMUSG00000033714 +12047 Bcl2a1d MGI:MGI:1278325|Ensembl:ENSMUSG00000099974|Vega:OTTMUSG00000045606 +12048 Bcl2l1 MGI:MGI:88139|Ensembl:ENSMUSG00000007659|Vega:OTTMUSG00000015815 +12049 Bcl2l10 MGI:MGI:1330841|Ensembl:ENSMUSG00000032191 +12050 Bcl2l2 MGI:MGI:108052|Ensembl:ENSMUSG00000089682|Vega:OTTMUSG00000032812 +12051 Bcl3 MGI:MGI:88140|Ensembl:ENSMUSG00000053175|Vega:OTTMUSG00000031375 +12053 Bcl6 MGI:MGI:107187|Ensembl:ENSMUSG00000022508|Vega:OTTMUSG00000027148 +12054 Bcl7b MGI:MGI:1332238|Ensembl:ENSMUSG00000029681|Vega:OTTMUSG00000026029 +12055 Bcl7c MGI:MGI:1332237|Ensembl:ENSMUSG00000030814|Vega:OTTMUSG00000023194 +12057 Opn1sw MGI:MGI:99438|Ensembl:ENSMUSG00000058831|Vega:OTTMUSG00000022747 +12059 bd MGI:MGI:88142 +12061 Bdkrb1 MGI:MGI:88144|Ensembl:ENSMUSG00000041347|Vega:OTTMUSG00000043609 +12062 Bdkrb2 MGI:MGI:102845|Ensembl:ENSMUSG00000021070 +12064 Bdnf MGI:MGI:88145|Ensembl:ENSMUSG00000048482|Vega:OTTMUSG00000015122 +12066 Bemv1 MGI:MGI:88147 +12067 Ube2n-ps1 MGI:MGI:894296 +12068 Bet1 MGI:MGI:1343104|Ensembl:ENSMUSG00000032757|Vega:OTTMUSG00000023841 +12069 Bex2 MGI:MGI:1338017|Ensembl:ENSMUSG00000042750|Vega:OTTMUSG00000018777 +12070 Bex3 MGI:MGI:1338016|Ensembl:ENSMUSG00000046432|Vega:OTTMUSG00000018688 +12075 Bfsp1 MGI:MGI:101770|Ensembl:ENSMUSG00000027420|Vega:OTTMUSG00000003120 +12091 Glb1 MGI:MGI:88151|Ensembl:ENSMUSG00000045594|Vega:OTTMUSG00000062516 +12095 Bglap3 MGI:MGI:88155|Ensembl:ENSMUSG00000074489|Vega:OTTMUSG00000022057 +12096 Bglap MGI:MGI:88156|Ensembl:ENSMUSG00000074483|Vega:OTTMUSG00000022060 +12097 Bglap2 MGI:MGI:88157|Ensembl:ENSMUSG00000074486|Vega:OTTMUSG00000022061 +12111 Bgn MGI:MGI:88158|Ensembl:ENSMUSG00000031375|Vega:OTTMUSG00000017659 +12114 bh MGI:MGI:88159 +12116 Bhmt MGI:MGI:1339972|Ensembl:ENSMUSG00000074768|Vega:OTTMUSG00000024452 +12121 Bicd1 MGI:MGI:1101760|Ensembl:ENSMUSG00000003452|Vega:OTTMUSG00000026191 +12122 Bid MGI:MGI:108093|Ensembl:ENSMUSG00000004446|Vega:OTTMUSG00000024186 +12123 Hrk MGI:MGI:1201608|Ensembl:ENSMUSG00000046607|Vega:OTTMUSG00000044796 +12124 Bik MGI:MGI:1206591|Ensembl:ENSMUSG00000016758 +12125 Bcl2l11 MGI:MGI:1197519|Ensembl:ENSMUSG00000027381|Vega:OTTMUSG00000015356 +12131 Bkm1 MGI:MGI:88161 +12140 Fabp7 MGI:MGI:101916|Ensembl:ENSMUSG00000019874|Vega:OTTMUSG00000035387 +12142 Prdm1 MGI:MGI:99655|Ensembl:ENSMUSG00000038151|Vega:OTTMUSG00000035215 +12143 Blk MGI:MGI:88169|Ensembl:ENSMUSG00000014453 +12144 Blm MGI:MGI:1328362|Ensembl:ENSMUSG00000030528|Vega:OTTMUSG00000058676 +12145 Cxcr5 MGI:MGI:103567|Ensembl:ENSMUSG00000047880|Vega:OTTMUSG00000063345 +12151 Bmi1 MGI:MGI:88174|Ensembl:ENSMUSG00000026739|Vega:OTTMUSG00000011429 +12153 Bmp1 MGI:MGI:88176|Ensembl:ENSMUSG00000022098 +12154 Bmp10 MGI:MGI:1338820|Ensembl:ENSMUSG00000030046|Vega:OTTMUSG00000057176 +12155 Bmp15 MGI:MGI:1316745|Ensembl:ENSMUSG00000023279|Vega:OTTMUSG00000016662 +12156 Bmp2 MGI:MGI:88177|Ensembl:ENSMUSG00000027358|Vega:OTTMUSG00000015653 +12159 Bmp4 MGI:MGI:88180|Ensembl:ENSMUSG00000021835|Vega:OTTMUSG00000019526 +12160 Bmp5 MGI:MGI:88181|Ensembl:ENSMUSG00000032179|Vega:OTTMUSG00000021529 +12161 Bmp6 MGI:MGI:88182|Ensembl:ENSMUSG00000039004 +12162 Bmp7 MGI:MGI:103302|Ensembl:ENSMUSG00000008999|Vega:OTTMUSG00000016684 +12163 Bmp8a MGI:MGI:104515|Ensembl:ENSMUSG00000032726|Vega:OTTMUSG00000008976 +12164 Bmp8b MGI:MGI:107335|Ensembl:ENSMUSG00000002384|Vega:OTTMUSG00000008937 +12165 Gdf2 MGI:MGI:1321394|Ensembl:ENSMUSG00000072625 +12166 Bmpr1a MGI:MGI:1338938|Ensembl:ENSMUSG00000021796|Vega:OTTMUSG00000036087 +12167 Bmpr1b MGI:MGI:107191|Ensembl:ENSMUSG00000052430|Vega:OTTMUSG00000025350 +12168 Bmpr2 MGI:MGI:1095407|Ensembl:ENSMUSG00000067336|Vega:OTTMUSG00000047258 +12169 Bmx MGI:MGI:1101778|Ensembl:ENSMUSG00000031377|Vega:OTTMUSG00000019502 +12173 Bnc1 MGI:MGI:1097164|Ensembl:ENSMUSG00000025105|Vega:OTTMUSG00000059204 +12175 Bnip2 MGI:MGI:109327|Ensembl:ENSMUSG00000011958|Vega:OTTMUSG00000030864 +12176 Bnip3 MGI:MGI:109326|Ensembl:ENSMUSG00000078566|Vega:OTTMUSG00000023046 +12177 Bnip3l MGI:MGI:1332659|Ensembl:ENSMUSG00000022051|Vega:OTTMUSG00000023686 +12180 Smyd1 MGI:MGI:104790|Ensembl:ENSMUSG00000055027|Vega:OTTMUSG00000022727 +12181 Bop1 MGI:MGI:1334460|Ensembl:ENSMUSG00000022557 +12182 Bst1 MGI:MGI:105370|Ensembl:ENSMUSG00000029082|Vega:OTTMUSG00000053753 +12183 Bpgm MGI:MGI:1098242|Ensembl:ENSMUSG00000038871|Vega:OTTMUSG00000014784 +12189 Brca1 MGI:MGI:104537|Ensembl:ENSMUSG00000017146|Vega:OTTMUSG00000002870 +12190 Brca2 MGI:MGI:109337|Ensembl:ENSMUSG00000041147|Vega:OTTMUSG00000055512 +12192 Zfp36l1 MGI:MGI:107946|Ensembl:ENSMUSG00000021127 +12193 Zfp36l2 MGI:MGI:107945|Ensembl:ENSMUSG00000045817|Vega:OTTMUSG00000020082 +12209 Brs3 MGI:MGI:1100501|Ensembl:ENSMUSG00000031130|Vega:OTTMUSG00000017788 +12211 Birc6 MGI:MGI:1276108|Ensembl:ENSMUSG00000024073|Vega:OTTMUSG00000042370 +12212 Chic1 MGI:MGI:1344694|Ensembl:ENSMUSG00000031327|Vega:OTTMUSG00000018247 +12215 Bsg MGI:MGI:88208|Ensembl:ENSMUSG00000023175|Vega:OTTMUSG00000042290 +12217 Bsn MGI:MGI:1277955|Ensembl:ENSMUSG00000032589|Vega:OTTMUSG00000016899 +12222 bt2 MGI:MGI:88213 +12223 Btc MGI:MGI:99439|Ensembl:ENSMUSG00000082361|Vega:OTTMUSG00000055524 +12224 Klf5 MGI:MGI:1338056|Ensembl:ENSMUSG00000005148 +12226 Btg1 MGI:MGI:88215|Ensembl:ENSMUSG00000036478 +12227 Btg2 MGI:MGI:108384|Ensembl:ENSMUSG00000020423|Vega:OTTMUSG00000034725 +12228 Btg3 MGI:MGI:109532|Ensembl:ENSMUSG00000022863|Vega:OTTMUSG00000026522 +12229 Btk MGI:MGI:88216|Ensembl:ENSMUSG00000031264|Vega:OTTMUSG00000019307 +12231 Btn1a1 MGI:MGI:103118|Ensembl:ENSMUSG00000000706|Vega:OTTMUSG00000000742 +12234 Btrc MGI:MGI:1338871|Ensembl:ENSMUSG00000025217 +12235 Bub1 MGI:MGI:1100510|Ensembl:ENSMUSG00000027379|Vega:OTTMUSG00000016093 +12236 Bub1b MGI:MGI:1333889|Ensembl:ENSMUSG00000040084|Vega:OTTMUSG00000015367 +12237 Bub3 MGI:MGI:1343463|Ensembl:ENSMUSG00000066979|Vega:OTTMUSG00000059881 +12238 Commd3 MGI:MGI:88218|Ensembl:ENSMUSG00000051154|Vega:OTTMUSG00000011428 +12256 Bxv1 MGI:MGI:88221 +12257 Tspo MGI:MGI:88222|Ensembl:ENSMUSG00000041736|Vega:OTTMUSG00000059921 +12258 Serping1 MGI:MGI:894696|Ensembl:ENSMUSG00000023224|Vega:OTTMUSG00000013680 +12259 C1qa MGI:MGI:88223|Ensembl:ENSMUSG00000036887|Vega:OTTMUSG00000009765 +12260 C1qb MGI:MGI:88224|Ensembl:ENSMUSG00000036905|Vega:OTTMUSG00000009766 +12261 C1qbp MGI:MGI:1194505|Ensembl:ENSMUSG00000018446|Vega:OTTMUSG00000006079 +12262 C1qc MGI:MGI:88225|Ensembl:ENSMUSG00000036896|Vega:OTTMUSG00000009764 +12263 C2 MGI:MGI:88226|Ensembl:ENSMUSG00000024371|Vega:OTTMUSG00000034003 +12265 Ciita MGI:MGI:108445|Ensembl:ENSMUSG00000022504 +12266 C3 MGI:MGI:88227|Ensembl:ENSMUSG00000024164|Vega:OTTMUSG00000042133 +12267 C3ar1 MGI:MGI:1097680|Ensembl:ENSMUSG00000040552|Vega:OTTMUSG00000034575 +12268 C4b MGI:MGI:88228|Ensembl:ENSMUSG00000073418|Vega:OTTMUSG00000037255 +12269 C4bp MGI:MGI:88229|Ensembl:ENSMUSG00000026405|Vega:OTTMUSG00000030002 +12270 C4bp-ps1 MGI:MGI:99594 +12273 C5ar1 MGI:MGI:88232|Ensembl:ENSMUSG00000049130|Vega:OTTMUSG00000060709 +12274 C6 MGI:MGI:88233|Ensembl:ENSMUSG00000022181|Vega:OTTMUSG00000032527 +12279 C9 MGI:MGI:1098282|Ensembl:ENSMUSG00000022149|Vega:OTTMUSG00000026361 +12281 cab MGI:MGI:88239 +12282 Hyou1 MGI:MGI:108030|Ensembl:ENSMUSG00000032115|Vega:OTTMUSG00000034194 +12283 Cab39 MGI:MGI:107438|Ensembl:ENSMUSG00000036707|Vega:OTTMUSG00000021589 +12285 cac MGI:MGI:88240 +12286 Cacna1a MGI:MGI:109482|Ensembl:ENSMUSG00000034656|Vega:OTTMUSG00000031448 +12287 Cacna1b MGI:MGI:88296|Ensembl:ENSMUSG00000004113|Vega:OTTMUSG00000012011 +12288 Cacna1c MGI:MGI:103013|Ensembl:ENSMUSG00000051331|Vega:OTTMUSG00000049004 +12289 Cacna1d MGI:MGI:88293|Ensembl:ENSMUSG00000015968 +12290 Cacna1e MGI:MGI:106217|Ensembl:ENSMUSG00000004110|Vega:OTTMUSG00000049818 +12291 Cacna1g MGI:MGI:1201678|Ensembl:ENSMUSG00000020866|Vega:OTTMUSG00000001890 +12292 Cacna1s MGI:MGI:88294|Ensembl:ENSMUSG00000026407|Vega:OTTMUSG00000033761 +12293 Cacna2d1 MGI:MGI:88295|Ensembl:ENSMUSG00000040118|Vega:OTTMUSG00000055290 +12294 Cacna2d3 MGI:MGI:1338890|Ensembl:ENSMUSG00000021991|Vega:OTTMUSG00000046735 +12295 Cacnb1 MGI:MGI:102522|Ensembl:ENSMUSG00000020882|Vega:OTTMUSG00000002912 +12296 Cacnb2 MGI:MGI:894644|Ensembl:ENSMUSG00000057914|Vega:OTTMUSG00000011219 +12297 Cacnb3 MGI:MGI:103307|Ensembl:ENSMUSG00000003352 +12298 Cacnb4 MGI:MGI:103301|Ensembl:ENSMUSG00000017412|Vega:OTTMUSG00000012607 +12299 Cacng1 MGI:MGI:1206582|Ensembl:ENSMUSG00000020722|Vega:OTTMUSG00000003106 +12300 Cacng2 MGI:MGI:1316660|Ensembl:ENSMUSG00000019146|Vega:OTTMUSG00000016425 +12301 Cacybp MGI:MGI:1270839|Ensembl:ENSMUSG00000014226|Vega:OTTMUSG00000050680 +12304 Pdia4 MGI:MGI:104864|Ensembl:ENSMUSG00000025823|Vega:OTTMUSG00000057218 +12305 Ddr1 MGI:MGI:99216|Ensembl:ENSMUSG00000003534|Vega:OTTMUSG00000031017 +12306 Anxa2 MGI:MGI:88246|Ensembl:ENSMUSG00000032231|Vega:OTTMUSG00000030907 +12307 Calb1 MGI:MGI:88248|Ensembl:ENSMUSG00000028222|Vega:OTTMUSG00000004637 +12308 Calb2 MGI:MGI:101914|Ensembl:ENSMUSG00000003657|Vega:OTTMUSG00000061890 +12309 S100g MGI:MGI:104528|Ensembl:ENSMUSG00000040808|Vega:OTTMUSG00000019493 +12310 Calca MGI:MGI:2151253|Ensembl:ENSMUSG00000030669|Vega:OTTMUSG00000058696 +12311 Calcr MGI:MGI:101950|Ensembl:ENSMUSG00000023964|Vega:OTTMUSG00000035628 +12313 Calm1 MGI:MGI:88251|Ensembl:ENSMUSG00000001175|Vega:OTTMUSG00000016979 +12314 Calm2 MGI:MGI:103250|Ensembl:ENSMUSG00000036438|Vega:OTTMUSG00000022552 +12315 Calm3 MGI:MGI:103249|Ensembl:ENSMUSG00000019370|Vega:OTTMUSG00000022550 +12316 Aspm MGI:MGI:1334448|Ensembl:ENSMUSG00000033952|Vega:OTTMUSG00000019630 +12317 Calr MGI:MGI:88252|Ensembl:ENSMUSG00000003814|Vega:OTTMUSG00000022277 +12319 Car8 MGI:MGI:88253|Ensembl:ENSMUSG00000041261|Vega:OTTMUSG00000004323 +12321 Calu MGI:MGI:1097158|Ensembl:ENSMUSG00000029767|Vega:OTTMUSG00000024995 +12322 Camk2a MGI:MGI:88256|Ensembl:ENSMUSG00000024617|Vega:OTTMUSG00000016302 +12323 Camk2b MGI:MGI:88257|Ensembl:ENSMUSG00000057897|Vega:OTTMUSG00000005105 +12325 Camk2g MGI:MGI:88259|Ensembl:ENSMUSG00000021820 +12326 Camk4 MGI:MGI:88258|Ensembl:ENSMUSG00000038128 +12328 Caml MGI:MGI:104728|Ensembl:ENSMUSG00000021501|Vega:OTTMUSG00000035499 +12329 can MGI:MGI:88260 +12330 Canx MGI:MGI:88261|Ensembl:ENSMUSG00000020368|Vega:OTTMUSG00000005582 +12331 Cap1 MGI:MGI:88262|Ensembl:ENSMUSG00000028656|Vega:OTTMUSG00000008872 +12332 Capg MGI:MGI:1098259|Ensembl:ENSMUSG00000056737|Vega:OTTMUSG00000022323 +12333 Capn1 MGI:MGI:88263|Ensembl:ENSMUSG00000024942 +12334 Capn2 MGI:MGI:88264|Ensembl:ENSMUSG00000026509|Vega:OTTMUSG00000050407 +12335 Capn3 MGI:MGI:107437|Ensembl:ENSMUSG00000079110|Vega:OTTMUSG00000015381 +12336 Capns1 MGI:MGI:88266|Ensembl:ENSMUSG00000001794|Vega:OTTMUSG00000022203 +12337 Capn5 MGI:MGI:1100859|Ensembl:ENSMUSG00000035547|Vega:OTTMUSG00000022532 +12338 Capn6 MGI:MGI:1100850|Ensembl:ENSMUSG00000067276|Vega:OTTMUSG00000018841 +12339 Capn7 MGI:MGI:1338030|Ensembl:ENSMUSG00000021893|Vega:OTTMUSG00000027910 +12340 Capza1 MGI:MGI:106227|Ensembl:ENSMUSG00000070372|Vega:OTTMUSG00000022229 +12343 Capza2 MGI:MGI:106222|Ensembl:ENSMUSG00000015733|Vega:OTTMUSG00000016383 +12344 Capza3 MGI:MGI:106221|Ensembl:ENSMUSG00000041791|Vega:OTTMUSG00000023675 +12345 Capzb MGI:MGI:104652|Ensembl:ENSMUSG00000028745|Vega:OTTMUSG00000009900 +12346 Car1 MGI:MGI:88268|Ensembl:ENSMUSG00000027556|Vega:OTTMUSG00000026455 +12348 Car11 MGI:MGI:1336193|Ensembl:ENSMUSG00000003273|Vega:OTTMUSG00000031338 +12349 Car2 MGI:MGI:88269|Ensembl:ENSMUSG00000027562|Vega:OTTMUSG00000051087 +12350 Car3 MGI:MGI:88270|Ensembl:ENSMUSG00000027559|Vega:OTTMUSG00000051086 +12351 Car4 MGI:MGI:1096574|Ensembl:ENSMUSG00000000805|Vega:OTTMUSG00000001034 +12352 Car5a MGI:MGI:101946|Ensembl:ENSMUSG00000025317|Vega:OTTMUSG00000031066 +12353 Car6 MGI:MGI:1333786|Ensembl:ENSMUSG00000028972|Vega:OTTMUSG00000010399 +12354 Car7 MGI:MGI:103100|Ensembl:ENSMUSG00000031883|Vega:OTTMUSG00000029166 +12355 Nr1i3 MGI:MGI:1346307|Ensembl:ENSMUSG00000005677|Vega:OTTMUSG00000022426 +12359 Cat MGI:MGI:88271|Ensembl:ENSMUSG00000027187|Vega:OTTMUSG00000014875 +12361 Cask MGI:MGI:1309489|Ensembl:ENSMUSG00000031012|Vega:OTTMUSG00000016907 +12362 Casp1 MGI:MGI:96544|Ensembl:ENSMUSG00000025888 +12363 Casp4 MGI:MGI:107700|Ensembl:ENSMUSG00000033538|Vega:OTTMUSG00000033830 +12364 Casp12 MGI:MGI:1312922|Ensembl:ENSMUSG00000025887|Vega:OTTMUSG00000033710 +12365 Casp14 MGI:MGI:1335092|Ensembl:ENSMUSG00000005355 +12366 Casp2 MGI:MGI:97295|Ensembl:ENSMUSG00000029863|Vega:OTTMUSG00000023653 +12367 Casp3 MGI:MGI:107739|Ensembl:ENSMUSG00000031628|Vega:OTTMUSG00000061297 +12368 Casp6 MGI:MGI:1312921|Ensembl:ENSMUSG00000027997|Vega:OTTMUSG00000028845 +12369 Casp7 MGI:MGI:109383|Ensembl:ENSMUSG00000025076 +12370 Casp8 MGI:MGI:1261423|Ensembl:ENSMUSG00000026029|Vega:OTTMUSG00000047216 +12371 Casp9 MGI:MGI:1277950|Ensembl:ENSMUSG00000028914|Vega:OTTMUSG00000009932 +12372 Casq1 MGI:MGI:1309468|Ensembl:ENSMUSG00000007122|Vega:OTTMUSG00000035165 +12373 Casq2 MGI:MGI:1309469|Ensembl:ENSMUSG00000027861|Vega:OTTMUSG00000031087 +12374 Casr MGI:MGI:1351351|Ensembl:ENSMUSG00000051980|Vega:OTTMUSG00000037977 +12380 Cast MGI:MGI:1098236|Ensembl:ENSMUSG00000021585 +12385 Ctnna1 MGI:MGI:88274|Ensembl:ENSMUSG00000037815 +12386 Ctnna2 MGI:MGI:88275|Ensembl:ENSMUSG00000063063|Vega:OTTMUSG00000034530 +12387 Ctnnb1 MGI:MGI:88276|Ensembl:ENSMUSG00000006932|Vega:OTTMUSG00000016490 +12388 Ctnnd1 MGI:MGI:105100|Ensembl:ENSMUSG00000034101|Ensembl:ENSMUSG00000101645|Vega:OTTMUSG00000013442|Vega:OTTMUSG00000045966 +12389 Cav1 MGI:MGI:102709|Ensembl:ENSMUSG00000007655|Vega:OTTMUSG00000024023 +12390 Cav2 MGI:MGI:107571|Ensembl:ENSMUSG00000000058|Vega:OTTMUSG00000024026 +12391 Cav3 MGI:MGI:107570|Ensembl:ENSMUSG00000062694|Vega:OTTMUSG00000056497 +12393 Runx2 MGI:MGI:99829|Ensembl:ENSMUSG00000039153|Vega:OTTMUSG00000033514 +12394 Runx1 MGI:MGI:99852|Ensembl:ENSMUSG00000022952|Vega:OTTMUSG00000049470 +12395 Runx1t1 MGI:MGI:104793|Ensembl:ENSMUSG00000006586|Vega:OTTMUSG00000004483 +12396 Cbfa2t2 MGI:MGI:1333833|Ensembl:ENSMUSG00000038533|Vega:OTTMUSG00000015790 +12397 Cbfa2t2-ps1 MGI:MGI:1333788 +12398 Cbfa2t3 MGI:MGI:1338013|Ensembl:ENSMUSG00000006362|Vega:OTTMUSG00000027605 +12399 Runx3 MGI:MGI:102672|Ensembl:ENSMUSG00000070691|Vega:OTTMUSG00000031877 +12400 Cbfb MGI:MGI:99851|Ensembl:ENSMUSG00000031885|Vega:OTTMUSG00000049550 +12401 Serpina6 MGI:MGI:88278|Ensembl:ENSMUSG00000060807|Vega:OTTMUSG00000027668 +12402 Cbl MGI:MGI:88279|Ensembl:ENSMUSG00000034342|Vega:OTTMUSG00000058274 +12404 Cbln1 MGI:MGI:88281|Ensembl:ENSMUSG00000031654|Vega:OTTMUSG00000061461 +12405 Cbln2 MGI:MGI:88282|Ensembl:ENSMUSG00000024647|Vega:OTTMUSG00000028187 +12406 Serpinh1 MGI:MGI:88283|Ensembl:ENSMUSG00000070436|Vega:OTTMUSG00000058974 +12408 Cbr1 MGI:MGI:88284|Ensembl:ENSMUSG00000051483|Vega:OTTMUSG00000019917 +12409 Cbr2 MGI:MGI:107200|Ensembl:ENSMUSG00000025150|Vega:OTTMUSG00000004120 +12411 Cbs MGI:MGI:88285|Ensembl:ENSMUSG00000024039|Vega:OTTMUSG00000030973 +12412 Cbx1 MGI:MGI:105369|Ensembl:ENSMUSG00000018666|Vega:OTTMUSG00000001636 +12416 Cbx2 MGI:MGI:88289|Ensembl:ENSMUSG00000025577|Vega:OTTMUSG00000003981 +12417 Cbx3 MGI:MGI:108515|Ensembl:ENSMUSG00000029836|Vega:OTTMUSG00000017280 +12418 Cbx4 MGI:MGI:1195985|Ensembl:ENSMUSG00000039989|Vega:OTTMUSG00000003998 +12419 Cbx5 MGI:MGI:109372|Ensembl:ENSMUSG00000009575|Vega:OTTMUSG00000030240 +12420 cby MGI:MGI:88290 +12421 Rb1cc1 MGI:MGI:1341850|Ensembl:ENSMUSG00000025907|Vega:OTTMUSG00000033467 +12424 Cck MGI:MGI:88297|Ensembl:ENSMUSG00000032532|Vega:OTTMUSG00000062636 +12425 Cckar MGI:MGI:99478|Ensembl:ENSMUSG00000029193|Vega:OTTMUSG00000054616 +12426 Cckbr MGI:MGI:99479|Ensembl:ENSMUSG00000030898|Vega:OTTMUSG00000042484 +12427 Ccna1 MGI:MGI:108042|Ensembl:ENSMUSG00000027793|Vega:OTTMUSG00000053079 +12428 Ccna2 MGI:MGI:108069|Ensembl:ENSMUSG00000027715|Vega:OTTMUSG00000006485 +12442 Ccnb2 MGI:MGI:88311|Ensembl:ENSMUSG00000032218|Vega:OTTMUSG00000063622 +12443 Ccnd1 MGI:MGI:88313|Ensembl:ENSMUSG00000070348|Vega:OTTMUSG00000026018 +12444 Ccnd2 MGI:MGI:88314|Ensembl:ENSMUSG00000000184|Vega:OTTMUSG00000056347 +12445 Ccnd3 MGI:MGI:88315|Ensembl:ENSMUSG00000034165|Vega:OTTMUSG00000044411 +12447 Ccne1 MGI:MGI:88316|Ensembl:ENSMUSG00000002068|Vega:OTTMUSG00000022262 +12448 Ccne2 MGI:MGI:1329034|Ensembl:ENSMUSG00000028212|Vega:OTTMUSG00000004537 +12449 Ccnf MGI:MGI:102551|Ensembl:ENSMUSG00000072082 +12450 Ccng1 MGI:MGI:102890|Ensembl:ENSMUSG00000020326|Vega:OTTMUSG00000005434 +12452 Ccng2 MGI:MGI:1095734|Ensembl:ENSMUSG00000029385|Vega:OTTMUSG00000026614 +12453 Ccni MGI:MGI:1341077|Ensembl:ENSMUSG00000063015|Vega:OTTMUSG00000026616 +12454 Ccnk MGI:MGI:1276106|Ensembl:ENSMUSG00000021258 +12455 Ccnt1 MGI:MGI:1328363|Ensembl:ENSMUSG00000011960|Vega:OTTMUSG00000035789 +12456 Ccpn-ps MGI:MGI:109504 +12457 Noct MGI:MGI:109382|Ensembl:ENSMUSG00000023087|Vega:OTTMUSG00000027519 +12458 Ccr6 MGI:MGI:1333797|Ensembl:ENSMUSG00000040899 +12460 Ccs MGI:MGI:1333783|Ensembl:ENSMUSG00000034108 +12461 Cct2 MGI:MGI:107186|Ensembl:ENSMUSG00000034024 +12462 Cct3 MGI:MGI:104708|Ensembl:ENSMUSG00000001416|Vega:OTTMUSG00000035166 +12464 Cct4 MGI:MGI:104689|Ensembl:ENSMUSG00000007739|Vega:OTTMUSG00000005269 +12465 Cct5 MGI:MGI:107185|Ensembl:ENSMUSG00000022234|Vega:OTTMUSG00000030800 +12466 Cct6a MGI:MGI:107943 +12467 Cct6b MGI:MGI:1329013|Ensembl:ENSMUSG00000020698|Vega:OTTMUSG00000000914 +12468 Cct7 MGI:MGI:107184|Ensembl:ENSMUSG00000030007|Vega:OTTMUSG00000057881 +12469 Cct8 MGI:MGI:107183|Ensembl:ENSMUSG00000025613|Vega:OTTMUSG00000040145 +12475 Cd14 MGI:MGI:88318|Ensembl:ENSMUSG00000051439 +12476 Cd151 MGI:MGI:1096360|Ensembl:ENSMUSG00000025510|Vega:OTTMUSG00000060219 +12477 Ctla4 MGI:MGI:88556|Ensembl:ENSMUSG00000026011|Vega:OTTMUSG00000002278 +12478 Cd19 MGI:MGI:88319|Ensembl:ENSMUSG00000030724|Vega:OTTMUSG00000058214 +12479 Cd1d1 MGI:MGI:107674|Ensembl:ENSMUSG00000028076|Vega:OTTMUSG00000024396 +12480 Cd1d2 MGI:MGI:107675|Ensembl:ENSMUSG00000041750|Vega:OTTMUSG00000051766 +12481 Cd2 MGI:MGI:88320|Ensembl:ENSMUSG00000027863|Vega:OTTMUSG00000007104 +12482 Ms4a1 MGI:MGI:88321|Ensembl:ENSMUSG00000024673|Vega:OTTMUSG00000047066 +12483 Cd22 MGI:MGI:88322|Ensembl:ENSMUSG00000030577|Vega:OTTMUSG00000049771 +12484 Cd24a MGI:MGI:88323|Ensembl:ENSMUSG00000047139|Vega:OTTMUSG00000063496 +12487 Cd28 MGI:MGI:88327|Ensembl:ENSMUSG00000026012|Vega:OTTMUSG00000002254 +12488 Cd2ap MGI:MGI:1330281|Ensembl:ENSMUSG00000061665 +12489 Cd33 MGI:MGI:99440|Ensembl:ENSMUSG00000004609|Vega:OTTMUSG00000058533 +12490 Cd34 MGI:MGI:88329|Ensembl:ENSMUSG00000016494|Vega:OTTMUSG00000050886 +12491 Cd36 MGI:MGI:107899|Ensembl:ENSMUSG00000002944|Vega:OTTMUSG00000053047 +12492 Scarb2 MGI:MGI:1196458|Ensembl:ENSMUSG00000029426|Vega:OTTMUSG00000055604 +12493 Cd37 MGI:MGI:88330|Ensembl:ENSMUSG00000030798|Vega:OTTMUSG00000025381 +12494 Cd38 MGI:MGI:107474|Ensembl:ENSMUSG00000029084|Vega:OTTMUSG00000029024 +12495 Entpd1 MGI:MGI:102805|Ensembl:ENSMUSG00000048120|Vega:OTTMUSG00000029031 +12496 Entpd2 MGI:MGI:1096863|Ensembl:ENSMUSG00000015085|Vega:OTTMUSG00000012029 +12497 Entpd6 MGI:MGI:1202295|Ensembl:ENSMUSG00000033068|Vega:OTTMUSG00000015756 +12499 Entpd5 MGI:MGI:1321385|Ensembl:ENSMUSG00000021236|Vega:OTTMUSG00000027582 +12500 Cd3d MGI:MGI:88331|Ensembl:ENSMUSG00000032094|Vega:OTTMUSG00000063397 +12501 Cd3e MGI:MGI:88332|Ensembl:ENSMUSG00000032093|Vega:OTTMUSG00000016712 +12502 Cd3g MGI:MGI:88333|Ensembl:ENSMUSG00000002033|Vega:OTTMUSG00000034601 +12503 Cd247 MGI:MGI:88334|Ensembl:ENSMUSG00000005763|Vega:OTTMUSG00000034863 +12504 Cd4 MGI:MGI:88335|Ensembl:ENSMUSG00000023274|Vega:OTTMUSG00000023420 +12505 Cd44 MGI:MGI:88338|Ensembl:ENSMUSG00000005087|Vega:OTTMUSG00000014837 +12506 Cd48 MGI:MGI:88339|Ensembl:ENSMUSG00000015355|Vega:OTTMUSG00000016904 +12507 Cd5 MGI:MGI:88340|Ensembl:ENSMUSG00000024669 +12508 Cd53 MGI:MGI:88341|Ensembl:ENSMUSG00000040747|Vega:OTTMUSG00000052103 +12509 Cd59a MGI:MGI:109177|Ensembl:ENSMUSG00000032679|Vega:OTTMUSG00000014930 +12511 Cd6 MGI:MGI:103566|Ensembl:ENSMUSG00000024670|Vega:OTTMUSG00000036965 +12512 Cd63 MGI:MGI:99529|Ensembl:ENSMUSG00000025351 +12514 Cd68 MGI:MGI:88342|Ensembl:ENSMUSG00000018774|Vega:OTTMUSG00000006002 +12515 Cd69 MGI:MGI:88343|Ensembl:ENSMUSG00000030156|Vega:OTTMUSG00000056464 +12516 Cd7 MGI:MGI:88344|Ensembl:ENSMUSG00000025163|Vega:OTTMUSG00000004165 +12517 Cd72 MGI:MGI:88345|Ensembl:ENSMUSG00000028459|Vega:OTTMUSG00000006823 +12518 Cd79a MGI:MGI:101774|Ensembl:ENSMUSG00000003379|Vega:OTTMUSG00000029270 +12519 Cd80 MGI:MGI:101775|Ensembl:ENSMUSG00000075122 +12520 Cd81 MGI:MGI:1096398|Ensembl:ENSMUSG00000037706|Vega:OTTMUSG00000031887 +12521 Cd82 MGI:MGI:104651|Ensembl:ENSMUSG00000027215|Vega:OTTMUSG00000014545 +12522 Cd83 MGI:MGI:1328316|Ensembl:ENSMUSG00000015396 +12523 Cd84 MGI:MGI:1336885|Ensembl:ENSMUSG00000038147|Vega:OTTMUSG00000026928 +12524 Cd86 MGI:MGI:101773|Ensembl:ENSMUSG00000022901|Vega:OTTMUSG00000028661 +12525 Cd8a MGI:MGI:88346|Ensembl:ENSMUSG00000053977|Vega:OTTMUSG00000057913 +12526 Cd8b1 MGI:MGI:88347|Ensembl:ENSMUSG00000053044|Vega:OTTMUSG00000057911 +12527 Cd9 MGI:MGI:88348|Ensembl:ENSMUSG00000030342|Vega:OTTMUSG00000022694 +12530 Cdc25a MGI:MGI:103198|Ensembl:ENSMUSG00000032477|Vega:OTTMUSG00000051511 +12531 Cdc25b MGI:MGI:99701|Ensembl:ENSMUSG00000027330|Vega:OTTMUSG00000016040 +12532 Cdc25c MGI:MGI:88350|Ensembl:ENSMUSG00000044201 +12534 Cdk1 MGI:MGI:88351|Ensembl:ENSMUSG00000019942|Vega:OTTMUSG00000031247 +12537 Cdk11b MGI:MGI:88353|Ensembl:ENSMUSG00000029062|Vega:OTTMUSG00000010724 +12539 Cdc37 MGI:MGI:109531|Ensembl:ENSMUSG00000019471|Vega:OTTMUSG00000063152 +12540 Cdc42 MGI:MGI:106211|Ensembl:ENSMUSG00000006699|Vega:OTTMUSG00000009829 +12544 Cdc45 MGI:MGI:1338073|Ensembl:ENSMUSG00000000028|Vega:OTTMUSG00000026176 +12545 Cdc7 MGI:MGI:1309511|Ensembl:ENSMUSG00000029283|Vega:OTTMUSG00000028130 +12549 Arhgap31 MGI:MGI:1333857|Ensembl:ENSMUSG00000022799|Vega:OTTMUSG00000023288 +12550 Cdh1 MGI:MGI:88354|Ensembl:ENSMUSG00000000303|Vega:OTTMUSG00000020588 +12552 Cdh11 MGI:MGI:99217|Ensembl:ENSMUSG00000031673|Vega:OTTMUSG00000061430 +12554 Cdh13 MGI:MGI:99551|Ensembl:ENSMUSG00000031841|Vega:OTTMUSG00000031307 +12555 Cdh15 MGI:MGI:106672|Ensembl:ENSMUSG00000031962|Vega:OTTMUSG00000061871 +12556 Cdh16 MGI:MGI:106671|Ensembl:ENSMUSG00000031881|Vega:OTTMUSG00000061956 +12557 Cdh17 MGI:MGI:1095414|Ensembl:ENSMUSG00000028217|Vega:OTTMUSG00000004521 +12558 Cdh2 MGI:MGI:88355|Ensembl:ENSMUSG00000024304|Vega:OTTMUSG00000016310 +12560 Cdh3 MGI:MGI:88356|Ensembl:ENSMUSG00000061048|Vega:OTTMUSG00000061948 +12561 Cdh4 MGI:MGI:99218|Ensembl:ENSMUSG00000000305|Vega:OTTMUSG00000016217 +12562 Cdh5 MGI:MGI:105057|Ensembl:ENSMUSG00000031871|Vega:OTTMUSG00000061476 +12563 Cdh6 MGI:MGI:107435|Ensembl:ENSMUSG00000039385 +12564 Cdh8 MGI:MGI:107434|Ensembl:ENSMUSG00000036510|Vega:OTTMUSG00000025221 +12565 Cdh9 MGI:MGI:107433|Ensembl:ENSMUSG00000025370|Vega:OTTMUSG00000039791 +12566 Cdk2 MGI:MGI:104772|Ensembl:ENSMUSG00000025358 +12567 Cdk4 MGI:MGI:88357|Ensembl:ENSMUSG00000006728|Vega:OTTMUSG00000030604 +12568 Cdk5 MGI:MGI:101765|Ensembl:ENSMUSG00000028969|Vega:OTTMUSG00000053656 +12569 Cdk5r1 MGI:MGI:101764|Ensembl:ENSMUSG00000048895|Vega:OTTMUSG00000000218 +12570 Cdk5r2 MGI:MGI:1330828|Ensembl:ENSMUSG00000090071|Vega:OTTMUSG00000034759 +12571 Cdk6 MGI:MGI:1277162|Ensembl:ENSMUSG00000040274|Vega:OTTMUSG00000052940 +12572 Cdk7 MGI:MGI:102956|Ensembl:ENSMUSG00000069089 +12575 Cdkn1a MGI:MGI:104556|Ensembl:ENSMUSG00000023067|Vega:OTTMUSG00000031654 +12576 Cdkn1b MGI:MGI:104565|Ensembl:ENSMUSG00000003031|Vega:OTTMUSG00000021172 +12577 Cdkn1c MGI:MGI:104564|Ensembl:ENSMUSG00000037664|Vega:OTTMUSG00000060027 +12578 Cdkn2a MGI:MGI:104738|Ensembl:ENSMUSG00000044303|Vega:OTTMUSG00000007706 +12579 Cdkn2b MGI:MGI:104737|Ensembl:ENSMUSG00000073802 +12580 Cdkn2c MGI:MGI:105388|Ensembl:ENSMUSG00000028551|Vega:OTTMUSG00000008484 +12581 Cdkn2d MGI:MGI:105387|Ensembl:ENSMUSG00000096472|Vega:OTTMUSG00000063300 +12582 cdm MGI:MGI:88358 +12583 Cdo1 MGI:MGI:105925|Ensembl:ENSMUSG00000033022 +12585 Cdr2 MGI:MGI:1100885|Ensembl:ENSMUSG00000030878|Vega:OTTMUSG00000027358 +12587 Mia MGI:MGI:109615|Ensembl:ENSMUSG00000089661|Ensembl:ENSMUSG00000095538|Vega:OTTMUSG00000027206|Vega:OTTMUSG00000042285 +12589 Ift81 MGI:MGI:1098597|Ensembl:ENSMUSG00000029469|Vega:OTTMUSG00000026713 +12590 Cdx1 MGI:MGI:88360|Ensembl:ENSMUSG00000024619|Vega:OTTMUSG00000037224 +12591 Cdx2 MGI:MGI:88361|Ensembl:ENSMUSG00000029646|Vega:OTTMUSG00000037225 +12592 Cdx4 MGI:MGI:88362|Ensembl:ENSMUSG00000031326|Vega:OTTMUSG00000018245 +12593 Cdyl MGI:MGI:1339956|Ensembl:ENSMUSG00000059288 +12606 Cebpa MGI:MGI:99480|Ensembl:ENSMUSG00000034957|Vega:OTTMUSG00000058155 +12607 Cebpz MGI:MGI:109386|Ensembl:ENSMUSG00000024081 +12608 Cebpb MGI:MGI:88373|Ensembl:ENSMUSG00000056501|Vega:OTTMUSG00000016307 +12609 Cebpd MGI:MGI:103573|Ensembl:ENSMUSG00000071637|Vega:OTTMUSG00000060220 +12611 Cebpg MGI:MGI:104982|Ensembl:ENSMUSG00000056216|Vega:OTTMUSG00000032922 +12613 Cel MGI:MGI:88374|Ensembl:ENSMUSG00000026818|Vega:OTTMUSG00000011646 +12614 Celsr1 MGI:MGI:1100883|Ensembl:ENSMUSG00000016028 +12615 Cenpa MGI:MGI:88375|Ensembl:ENSMUSG00000029177|Vega:OTTMUSG00000022264 +12616 Cenpb MGI:MGI:88376|Ensembl:ENSMUSG00000068267|Vega:OTTMUSG00000015913 +12617 Cenpc1 MGI:MGI:99700|Ensembl:ENSMUSG00000029253|Vega:OTTMUSG00000053352 +12622 Cer1 MGI:MGI:1201414|Ensembl:ENSMUSG00000038192|Vega:OTTMUSG00000000410 +12623 Ces1g MGI:MGI:88378|Ensembl:ENSMUSG00000057074|Vega:OTTMUSG00000040118 +12624 Cet1 MGI:MGI:104863 +12626 Cetn3 MGI:MGI:1097706|Ensembl:ENSMUSG00000021537 +12627 Cfc1 MGI:MGI:109448|Ensembl:ENSMUSG00000026124|Vega:OTTMUSG00000049475 +12628 Cfh MGI:MGI:88385|Ensembl:ENSMUSG00000026365|Vega:OTTMUSG00000024648 +12630 Cfi MGI:MGI:105937|Ensembl:ENSMUSG00000058952|Vega:OTTMUSG00000054726 +12631 Cfl1 MGI:MGI:101757|Ensembl:ENSMUSG00000056201|Vega:OTTMUSG00000060221 +12632 Cfl2 MGI:MGI:101763|Ensembl:ENSMUSG00000062929 +12633 Cflar MGI:MGI:1336166|Ensembl:ENSMUSG00000026031|Vega:OTTMUSG00000019581 +12638 Cftr MGI:MGI:88388|Ensembl:ENSMUSG00000041301|Vega:OTTMUSG00000024173 +12640 Cga MGI:MGI:88390|Ensembl:ENSMUSG00000028298|Vega:OTTMUSG00000006474 +12642 Ch25h MGI:MGI:1333869|Ensembl:ENSMUSG00000050370 +12643 Chad MGI:MGI:1096866|Ensembl:ENSMUSG00000039084|Vega:OTTMUSG00000002018 +12647 Chat MGI:MGI:88392|Ensembl:ENSMUSG00000021919 +12648 Chd1 MGI:MGI:88393|Ensembl:ENSMUSG00000023852|Vega:OTTMUSG00000038131 +12649 Chek1 MGI:MGI:1202065|Ensembl:ENSMUSG00000032113|Vega:OTTMUSG00000037031 +12651 Chkb MGI:MGI:1328313|Ensembl:ENSMUSG00000022617|Vega:OTTMUSG00000035435 +12652 Chga MGI:MGI:88394|Ensembl:ENSMUSG00000021194 +12653 Chgb MGI:MGI:88395|Ensembl:ENSMUSG00000027350|Vega:OTTMUSG00000015662 +12654 Chil1 MGI:MGI:1340899|Ensembl:ENSMUSG00000064246|Vega:OTTMUSG00000030091 +12655 Chil3 MGI:MGI:1330860|Ensembl:ENSMUSG00000040809|Vega:OTTMUSG00000023699 +12659 Ovgp1 MGI:MGI:106661|Ensembl:ENSMUSG00000074340|Vega:OTTMUSG00000036417 +12660 Chka MGI:MGI:107760|Ensembl:ENSMUSG00000024843|Vega:OTTMUSG00000029650 +12661 Chl1 MGI:MGI:1098266|Ensembl:ENSMUSG00000030077|Vega:OTTMUSG00000057275 +12662 Chm MGI:MGI:892979|Ensembl:ENSMUSG00000025531|Vega:OTTMUSG00000018561 +12663 Chml MGI:MGI:101913|Ensembl:ENSMUSG00000078185|Vega:OTTMUSG00000021480 +12667 Chrd MGI:MGI:1313268|Ensembl:ENSMUSG00000006958|Vega:OTTMUSG00000021018 +12669 Chrm1 MGI:MGI:88396|Ensembl:ENSMUSG00000032773|Vega:OTTMUSG00000039794 +12671 Chrm3 MGI:MGI:88398|Ensembl:ENSMUSG00000046159|Vega:OTTMUSG00000048429 +12672 Chrm4 MGI:MGI:88399|Ensembl:ENSMUSG00000040495|Vega:OTTMUSG00000014365 +12675 Chuk MGI:MGI:99484|Ensembl:ENSMUSG00000025199|Vega:OTTMUSG00000029724 +12677 Vsx2 MGI:MGI:88401|Ensembl:ENSMUSG00000021239|Vega:OTTMUSG00000038498 +12679 ci MGI:MGI:88403 +12683 Cidea MGI:MGI:1270845|Ensembl:ENSMUSG00000024526 +12684 Cideb MGI:MGI:1270844|Ensembl:ENSMUSG00000022219|Vega:OTTMUSG00000027852 +12686 Elovl3 MGI:MGI:1195976|Ensembl:ENSMUSG00000038754|Vega:OTTMUSG00000023197 +12695 Patj MGI:MGI:1277960|Ensembl:ENSMUSG00000061859|Vega:OTTMUSG00000008476 +12696 Cirbp MGI:MGI:893588|Ensembl:ENSMUSG00000045193|Vega:OTTMUSG00000000003 +12700 Cish MGI:MGI:103159|Ensembl:ENSMUSG00000032578|Vega:OTTMUSG00000036835 +12702 Socs3 MGI:MGI:1201791|Ensembl:ENSMUSG00000053113|Vega:OTTMUSG00000003735 +12703 Socs1 MGI:MGI:1354910|Ensembl:ENSMUSG00000038037 +12704 Cit MGI:MGI:105313|Ensembl:ENSMUSG00000029516|Vega:OTTMUSG00000014714 +12705 Cited1 MGI:MGI:108023|Ensembl:ENSMUSG00000051159|Vega:OTTMUSG00000018307 +12706 Ckb-ps2 MGI:MGI:88404 +12707 Ck-ps2 MGI:MGI:88405 +12708 Ck-ps3 MGI:MGI:88406 +12709 Ckb MGI:MGI:88407|Ensembl:ENSMUSG00000001270 +12715 Ckm MGI:MGI:88413|Ensembl:ENSMUSG00000030399|Vega:OTTMUSG00000059190 +12716 Ckmt1 MGI:MGI:99441|Ensembl:ENSMUSG00000000308|Vega:OTTMUSG00000015261 +12717 ckr MGI:MGI:88414 +12718 ckrtgr MGI:MGI:1316694 +12720 cla MGI:MGI:88416 +12721 Coro1a MGI:MGI:1345961|Ensembl:ENSMUSG00000030707|Vega:OTTMUSG00000025099 +12722 Clca3a1 MGI:MGI:1316732|Ensembl:ENSMUSG00000056025|Vega:OTTMUSG00000026564 +12723 Clcn1 MGI:MGI:88417|Ensembl:ENSMUSG00000029862|Vega:OTTMUSG00000036880 +12724 Clcn2 MGI:MGI:105061|Ensembl:ENSMUSG00000022843|Vega:OTTMUSG00000028531 +12725 Clcn3 MGI:MGI:103555|Ensembl:ENSMUSG00000004319|Vega:OTTMUSG00000022342 +12727 Clcn4 MGI:MGI:104571|Ensembl:ENSMUSG00000000605|Vega:OTTMUSG00000037804 +12728 Clcn5 MGI:MGI:99486|Ensembl:ENSMUSG00000004317|Vega:OTTMUSG00000016484 +12729 Clns1a MGI:MGI:109638|Ensembl:ENSMUSG00000025439|Vega:OTTMUSG00000024489 +12733 Clcnka MGI:MGI:1329026|Ensembl:ENSMUSG00000033770|Vega:OTTMUSG00000010291 +12735 Clc MGI:MGI:891997 +12737 Cldn1 MGI:MGI:1276109|Ensembl:ENSMUSG00000022512|Vega:OTTMUSG00000022624 +12738 Cldn2 MGI:MGI:1276110|Ensembl:ENSMUSG00000047230|Vega:OTTMUSG00000018734 +12739 Cldn3 MGI:MGI:1329044|Ensembl:ENSMUSG00000070473|Vega:OTTMUSG00000022612 +12740 Cldn4 MGI:MGI:1313314|Ensembl:ENSMUSG00000047501|Vega:OTTMUSG00000055820 +12741 Cldn5 MGI:MGI:1276112|Ensembl:ENSMUSG00000041378 +12744 clf2 MGI:MGI:99671 +12745 Clgn MGI:MGI:107472|Ensembl:ENSMUSG00000002190|Vega:OTTMUSG00000022192 +12747 Clk1 MGI:MGI:107403|Ensembl:ENSMUSG00000026034|Vega:OTTMUSG00000021803 +12748 Clk2 MGI:MGI:1098669|Ensembl:ENSMUSG00000068917|Vega:OTTMUSG00000029741 +12750 Clk4 MGI:MGI:1098551|Ensembl:ENSMUSG00000020385|Vega:OTTMUSG00000005598 +12751 Tpp1 MGI:MGI:1336194|Ensembl:ENSMUSG00000030894|Vega:OTTMUSG00000060349 +12752 Cln3 MGI:MGI:107537|Ensembl:ENSMUSG00000030720|Vega:OTTMUSG00000019900 +12753 Clock MGI:MGI:99698|Ensembl:ENSMUSG00000029238|Vega:OTTMUSG00000056120 +12757 Clta MGI:MGI:894297|Ensembl:ENSMUSG00000028478|Vega:OTTMUSG00000007204 +12759 Clu MGI:MGI:88423|Ensembl:ENSMUSG00000022037|Vega:OTTMUSG00000032654 +12761 cma MGI:MGI:88425 +12763 Cmah MGI:MGI:103227|Ensembl:ENSMUSG00000016756|Vega:OTTMUSG00000000727 +12764 Cmas MGI:MGI:1337124|Ensembl:ENSMUSG00000030282|Vega:OTTMUSG00000023787 +12765 Cxcr2 MGI:MGI:105303|Ensembl:ENSMUSG00000026180|Vega:OTTMUSG00000047665 +12766 Cxcr3 MGI:MGI:1277207|Ensembl:ENSMUSG00000050232|Vega:OTTMUSG00000018202 +12767 Cxcr4 MGI:MGI:109563|Ensembl:ENSMUSG00000045382|Vega:OTTMUSG00000020918 +12768 Ccr1 MGI:MGI:104618|Ensembl:ENSMUSG00000025804|Vega:OTTMUSG00000062930 +12769 Ccr9 MGI:MGI:1341902|Ensembl:ENSMUSG00000029530|Vega:OTTMUSG00000036110 +12770 Ccr1l1 MGI:MGI:104617|Ensembl:ENSMUSG00000064039|Vega:OTTMUSG00000062931 +12771 Ccr3 MGI:MGI:104616|Ensembl:ENSMUSG00000035448|Vega:OTTMUSG00000062932 +12772 Ccr2 MGI:MGI:106185|Ensembl:ENSMUSG00000049103|Vega:OTTMUSG00000035281 +12773 Ccr4 MGI:MGI:107824|Ensembl:ENSMUSG00000047898|Vega:OTTMUSG00000062518 +12774 Ccr5 MGI:MGI:107182|Ensembl:ENSMUSG00000079227|Vega:OTTMUSG00000035282 +12775 Ccr7 MGI:MGI:103011|Ensembl:ENSMUSG00000037944|Vega:OTTMUSG00000006448 +12776 Ccr8 MGI:MGI:1201402|Ensembl:ENSMUSG00000042262|Vega:OTTMUSG00000062526 +12777 Ccr10 MGI:MGI:1096320|Ensembl:ENSMUSG00000044052|Vega:OTTMUSG00000002727 +12778 Ackr3 MGI:MGI:109562|Ensembl:ENSMUSG00000044337|Vega:OTTMUSG00000029162 +12780 Abcc2 MGI:MGI:1352447|Ensembl:ENSMUSG00000025194|Vega:OTTMUSG00000026258 +12785 Cnbp MGI:MGI:88431|Ensembl:ENSMUSG00000030057|Vega:OTTMUSG00000023465 +12788 Cnga1 MGI:MGI:88436|Ensembl:ENSMUSG00000067220|Vega:OTTMUSG00000026745 +12789 Cnga2 MGI:MGI:108040|Ensembl:ENSMUSG00000005864|Vega:OTTMUSG00000017812 +12790 Cnga3 MGI:MGI:1341818|Ensembl:ENSMUSG00000026114|Vega:OTTMUSG00000024612 +12793 Cnih1 MGI:MGI:1277202|Ensembl:ENSMUSG00000015759|Vega:OTTMUSG00000023897 +12794 Cnih2 MGI:MGI:1277225|Ensembl:ENSMUSG00000024873 +12795 Plk3 MGI:MGI:109604|Ensembl:ENSMUSG00000028680|Vega:OTTMUSG00000009922 +12796 Camp MGI:MGI:108443|Ensembl:ENSMUSG00000038357|Vega:OTTMUSG00000020575 +12797 Cnn1 MGI:MGI:104979|Ensembl:ENSMUSG00000001349|Vega:OTTMUSG00000062332 +12798 Cnn2 MGI:MGI:105093|Ensembl:ENSMUSG00000004665|Vega:OTTMUSG00000019132 +12799 Cnp MGI:MGI:88437|Ensembl:ENSMUSG00000006782|Vega:OTTMUSG00000002001 +12801 Cnr1 MGI:MGI:104615|Ensembl:ENSMUSG00000044288|Vega:OTTMUSG00000008304 +12802 Cnr2 MGI:MGI:104650|Ensembl:ENSMUSG00000062585|Vega:OTTMUSG00000009846 +12803 Cntf MGI:MGI:88439|Ensembl:ENSMUSG00000079415|Vega:OTTMUSG00000024775 +12804 Cntfr MGI:MGI:99605|Ensembl:ENSMUSG00000028444|Vega:OTTMUSG00000006676 +12805 Cntn1 MGI:MGI:105980|Ensembl:ENSMUSG00000055022|Vega:OTTMUSG00000014988 +12806 co MGI:MGI:88440 +12807 Hps3 MGI:MGI:2153839|Ensembl:ENSMUSG00000027615|Vega:OTTMUSG00000023502 +12808 Cobl MGI:MGI:105056|Ensembl:ENSMUSG00000020173|Vega:OTTMUSG00000005168 +12810 Coch MGI:MGI:1278313|Ensembl:ENSMUSG00000020953 +12811 cod MGI:MGI:88443 +12812 Coil MGI:MGI:104842|Ensembl:ENSMUSG00000033983|Vega:OTTMUSG00000001302 +12813 Col10a1 MGI:MGI:88445|Ensembl:ENSMUSG00000039462|Vega:OTTMUSG00000022505 +12814 Col11a1 MGI:MGI:88446|Ensembl:ENSMUSG00000027966|Vega:OTTMUSG00000022509 +12815 Col11a2 MGI:MGI:88447|Ensembl:ENSMUSG00000024330|Vega:OTTMUSG00000022512 +12816 Col12a1 MGI:MGI:88448|Ensembl:ENSMUSG00000032332|Vega:OTTMUSG00000021365 +12817 Col13a1 MGI:MGI:1277201|Ensembl:ENSMUSG00000058806|Vega:OTTMUSG00000021424 +12818 Col14a1 MGI:MGI:1341272|Ensembl:ENSMUSG00000022371|Vega:OTTMUSG00000021422 +12819 Col15a1 MGI:MGI:88449|Ensembl:ENSMUSG00000028339|Vega:OTTMUSG00000006798 +12821 Col17a1 MGI:MGI:88450|Ensembl:ENSMUSG00000025064|Vega:OTTMUSG00000021388 +12822 Col18a1 MGI:MGI:88451|Ensembl:ENSMUSG00000001435|Vega:OTTMUSG00000021408 +12823 Col19a1 MGI:MGI:1095415|Ensembl:ENSMUSG00000026141|Vega:OTTMUSG00000021418 +12824 Col2a1 MGI:MGI:88452|Ensembl:ENSMUSG00000022483|Vega:OTTMUSG00000021708 +12825 Col3a1 MGI:MGI:88453|Ensembl:ENSMUSG00000026043|Vega:OTTMUSG00000021335 +12826 Col4a1 MGI:MGI:88454|Ensembl:ENSMUSG00000031502|Vega:OTTMUSG00000021316 +12827 Col4a2 MGI:MGI:88455|Ensembl:ENSMUSG00000031503|Vega:OTTMUSG00000021317 +12828 Col4a3 MGI:MGI:104688|Ensembl:ENSMUSG00000079465|Vega:OTTMUSG00000021696 +12829 Col4a4 MGI:MGI:104687|Ensembl:ENSMUSG00000067158|Vega:OTTMUSG00000021695 +12830 Col4a5 MGI:MGI:88456|Ensembl:ENSMUSG00000031274|Vega:OTTMUSG00000018954 +12831 Col5a1 MGI:MGI:88457|Ensembl:ENSMUSG00000026837|Vega:OTTMUSG00000011567 +12832 Col5a2 MGI:MGI:88458|Ensembl:ENSMUSG00000026042|Vega:OTTMUSG00000021356 +12833 Col6a1 MGI:MGI:88459|Ensembl:ENSMUSG00000001119|Vega:OTTMUSG00000020489 +12834 Col6a2 MGI:MGI:88460|Ensembl:ENSMUSG00000020241|Vega:OTTMUSG00000020488 +12835 Col6a3 MGI:MGI:88461|Ensembl:ENSMUSG00000048126|Vega:OTTMUSG00000022359 +12836 Col7a1 MGI:MGI:88462|Ensembl:ENSMUSG00000025650|Vega:OTTMUSG00000021336 +12837 Col8a1 MGI:MGI:88463|Ensembl:ENSMUSG00000068196|Vega:OTTMUSG00000021291 +12839 Col9a1 MGI:MGI:88465|Ensembl:ENSMUSG00000026147|Vega:OTTMUSG00000022796 +12840 Col9a2 MGI:MGI:88466|Ensembl:ENSMUSG00000028626|Vega:OTTMUSG00000008902 +12841 Col9a3 MGI:MGI:894686|Ensembl:ENSMUSG00000027570|Vega:OTTMUSG00000016344 +12842 Col1a1 MGI:MGI:88467|Ensembl:ENSMUSG00000001506|Vega:OTTMUSG00000002059 +12843 Col1a2 MGI:MGI:88468|Ensembl:ENSMUSG00000029661|Vega:OTTMUSG00000021300 +12845 Comp MGI:MGI:88469|Ensembl:ENSMUSG00000031849|Vega:OTTMUSG00000062218 +12846 Comt MGI:MGI:88470|Ensembl:ENSMUSG00000000326|Vega:OTTMUSG00000026238 +12847 Copa MGI:MGI:1334462|Ensembl:ENSMUSG00000026553|Vega:OTTMUSG00000033968 +12848 Cops2 MGI:MGI:1330276|Ensembl:ENSMUSG00000027206|Vega:OTTMUSG00000015340 +12850 Coq7 MGI:MGI:107207|Ensembl:ENSMUSG00000030652|Vega:OTTMUSG00000025111 +12854 Cort MGI:MGI:109538|Ensembl:ENSMUSG00000028971|Vega:OTTMUSG00000010957 +12856 Cox17 MGI:MGI:1333806|Ensembl:ENSMUSG00000046516|Ensembl:ENSMUSG00000095464|Vega:OTTMUSG00000026953|Vega:OTTMUSG00000042289 +12857 Cox4i1 MGI:MGI:88473|Ensembl:ENSMUSG00000031818|Vega:OTTMUSG00000043013 +12858 Cox5a MGI:MGI:88474|Ensembl:ENSMUSG00000000088|Vega:OTTMUSG00000063187 +12859 Cox5b MGI:MGI:88475|Ensembl:ENSMUSG00000061518|Vega:OTTMUSG00000049480 +12861 Cox6a1 MGI:MGI:103099|Ensembl:ENSMUSG00000041697|Vega:OTTMUSG00000014656 +12862 Cox6a2 MGI:MGI:104649|Ensembl:ENSMUSG00000030785|Vega:OTTMUSG00000058671 +12864 Cox6c MGI:MGI:104614|Ensembl:ENSMUSG00000014313|Vega:OTTMUSG00000033854 +12865 Cox7a1 MGI:MGI:1316714|Ensembl:ENSMUSG00000074218|Vega:OTTMUSG00000059310 +12866 Cox7a2 MGI:MGI:1316715|Ensembl:ENSMUSG00000032330|Vega:OTTMUSG00000062962 +12867 Cox7c MGI:MGI:103226|Ensembl:ENSMUSG00000017778|Vega:OTTMUSG00000032917 +12868 Cox8a MGI:MGI:105959|Ensembl:ENSMUSG00000035885 +12869 Cox8b MGI:MGI:105958|Ensembl:ENSMUSG00000025488|Vega:OTTMUSG00000060377 +12870 Cp MGI:MGI:88476|Ensembl:ENSMUSG00000003617|Vega:OTTMUSG00000023513 +12873 Cpa3 MGI:MGI:88479|Ensembl:ENSMUSG00000001865|Vega:OTTMUSG00000051236 +12874 Cpd MGI:MGI:107265|Ensembl:ENSMUSG00000020841|Vega:OTTMUSG00000006239 +12876 Cpe MGI:MGI:101932|Ensembl:ENSMUSG00000037852|Vega:OTTMUSG00000061196 +12877 Cpeb1 MGI:MGI:108442|Ensembl:ENSMUSG00000025586|Vega:OTTMUSG00000024594 +12879 Cys1 MGI:MGI:2177632|Ensembl:ENSMUSG00000062563|Vega:OTTMUSG00000027562 +12889 Cplx1 MGI:MGI:104727|Ensembl:ENSMUSG00000033615|Vega:OTTMUSG00000028893 +12890 Cplx2 MGI:MGI:104726|Ensembl:ENSMUSG00000025867|Vega:OTTMUSG00000032656 +12891 Cpne6 MGI:MGI:1334445|Ensembl:ENSMUSG00000022212|Vega:OTTMUSG00000035549 +12892 Cpox MGI:MGI:104841|Ensembl:ENSMUSG00000022742 +12894 Cpt1a MGI:MGI:1098296|Ensembl:ENSMUSG00000024900 +12895 Cpt1b MGI:MGI:1098297|Ensembl:ENSMUSG00000078937|Vega:OTTMUSG00000035434 +12896 Cpt2 MGI:MGI:109176|Ensembl:ENSMUSG00000028607|Vega:OTTMUSG00000009301 +12898 cpy MGI:MGI:88486 +12902 Cr2 MGI:MGI:88489|Ensembl:ENSMUSG00000026616|Vega:OTTMUSG00000050897 +12903 Crabp1 MGI:MGI:88490|Ensembl:ENSMUSG00000032291|Vega:OTTMUSG00000030283 +12904 Crabp2 MGI:MGI:88491|Ensembl:ENSMUSG00000004885|Vega:OTTMUSG00000027199 +12905 Cradd MGI:MGI:1336168|Ensembl:ENSMUSG00000045867 +12908 Crat MGI:MGI:109501|Ensembl:ENSMUSG00000026853|Vega:OTTMUSG00000016795 +12909 Crcp MGI:MGI:1100818|Ensembl:ENSMUSG00000025532|Vega:OTTMUSG00000022713 +12912 Creb1 MGI:MGI:88494|Ensembl:ENSMUSG00000025958|Vega:OTTMUSG00000047617 +12913 Creb3 MGI:MGI:99946|Ensembl:ENSMUSG00000028466|Vega:OTTMUSG00000006960 +12914 Crebbp MGI:MGI:1098280|Ensembl:ENSMUSG00000022521|Vega:OTTMUSG00000048175 +12915 Atf6b MGI:MGI:105121|Ensembl:ENSMUSG00000015461|Vega:OTTMUSG00000037081 +12916 Crem MGI:MGI:88495|Ensembl:ENSMUSG00000063889|Vega:OTTMUSG00000033204 +12917 crf MGI:MGI:1289180 +12918 Crh MGI:MGI:88496|Ensembl:ENSMUSG00000049796|Vega:OTTMUSG00000051234 +12919 Crhbp MGI:MGI:88497|Ensembl:ENSMUSG00000021680 +12921 Crhr1 MGI:MGI:88498|Ensembl:ENSMUSG00000018634|Vega:OTTMUSG00000003151 +12922 Crhr2 MGI:MGI:894312|Ensembl:ENSMUSG00000003476|Vega:OTTMUSG00000035963 +12923 crhx MGI:MGI:88499 +12924 cri MGI:MGI:88500 +12925 Crip1 MGI:MGI:88501|Ensembl:ENSMUSG00000006360|Vega:OTTMUSG00000052481 +12927 Bcar1 MGI:MGI:108091|Ensembl:ENSMUSG00000031955|Vega:OTTMUSG00000061802 +12928 Crk MGI:MGI:88508|Ensembl:ENSMUSG00000017776|Vega:OTTMUSG00000006211 +12929 Crkl MGI:MGI:104686|Ensembl:ENSMUSG00000006134|Vega:OTTMUSG00000025644 +12931 Crlf1 MGI:MGI:1340030|Ensembl:ENSMUSG00000007888|Vega:OTTMUSG00000033461 +12933 Crmp1 MGI:MGI:107793|Ensembl:ENSMUSG00000029121|Vega:OTTMUSG00000056097 +12934 Dpysl2 MGI:MGI:1349763|Ensembl:ENSMUSG00000022048|Vega:OTTMUSG00000016382 +12935 crn MGI:MGI:88511 +12936 Pcdha4 MGI:MGI:1298406|Ensembl:ENSMUSG00000104252|Vega:OTTMUSG00000050588 +12937 Pcdha6 MGI:MGI:1298367|Ensembl:ENSMUSG00000103707|Vega:OTTMUSG00000050610 +12939 Pcdha7 MGI:MGI:1298369|Ensembl:ENSMUSG00000104318|Vega:OTTMUSG00000050611 +12941 Pcdha5 MGI:MGI:1298371|Ensembl:ENSMUSG00000103092|Vega:OTTMUSG00000050592 +12942 Pcdha11 MGI:MGI:1298372|Ensembl:ENSMUSG00000102206|Vega:OTTMUSG00000050625 +12943 Pcdha10 MGI:MGI:1298408|Ensembl:ENSMUSG00000007440|Vega:OTTMUSG00000050623 +12944 Crp MGI:MGI:88512|Ensembl:ENSMUSG00000037942|Vega:OTTMUSG00000050157 +12945 Dmbt1 MGI:MGI:106210|Ensembl:ENSMUSG00000047517|Vega:OTTMUSG00000059749 +12946 Cr1l MGI:MGI:88513|Ensembl:ENSMUSG00000016481|Vega:OTTMUSG00000050896 +12948 crsp MGI:MGI:1313307 +12950 Hapln1 MGI:MGI:1337006|Ensembl:ENSMUSG00000021613 +12951 Crx MGI:MGI:1194883|Ensembl:ENSMUSG00000041578|Vega:OTTMUSG00000029352 +12952 Cry1 MGI:MGI:1270841|Ensembl:ENSMUSG00000020038|Vega:OTTMUSG00000063559 +12953 Cry2 MGI:MGI:1270859|Ensembl:ENSMUSG00000068742|Vega:OTTMUSG00000014483 +12954 Cryaa MGI:MGI:88515|Ensembl:ENSMUSG00000024041 +12955 Cryab MGI:MGI:88516|Ensembl:ENSMUSG00000032060|Vega:OTTMUSG00000063076 +12957 Cryba1 MGI:MGI:88518|Ensembl:ENSMUSG00000000724|Vega:OTTMUSG00000008185 +12958 Cryba2 MGI:MGI:104336|Ensembl:ENSMUSG00000006546|Vega:OTTMUSG00000020843 +12959 Cryba4 MGI:MGI:102716|Ensembl:ENSMUSG00000066975|Vega:OTTMUSG00000021278 +12960 Crybb1 MGI:MGI:104992|Ensembl:ENSMUSG00000029343|Vega:OTTMUSG00000024817 +12961 Crybb2 MGI:MGI:88519|Ensembl:ENSMUSG00000042240|Vega:OTTMUSG00000021314 +12962 Crybb3 MGI:MGI:102717|Ensembl:ENSMUSG00000029352|Vega:OTTMUSG00000026830 +12964 Cryga MGI:MGI:88521|Ensembl:ENSMUSG00000044429|Vega:OTTMUSG00000022111 +12965 Crygb MGI:MGI:88522|Ensembl:ENSMUSG00000073658|Vega:OTTMUSG00000047625 +12966 Crygc MGI:MGI:88523|Ensembl:ENSMUSG00000025952|Vega:OTTMUSG00000021759 +12967 Crygd MGI:MGI:88524|Ensembl:ENSMUSG00000067299|Vega:OTTMUSG00000033410 +12968 Cryge MGI:MGI:88525|Ensembl:ENSMUSG00000070870|Vega:OTTMUSG00000021574 +12969 Crygf MGI:MGI:88526|Ensembl:ENSMUSG00000025945|Vega:OTTMUSG00000024984 +12970 Crygs MGI:MGI:1298216|Ensembl:ENSMUSG00000033501 +12971 Crym MGI:MGI:102675|Ensembl:ENSMUSG00000030905|Vega:OTTMUSG00000027354 +12972 Cryz MGI:MGI:88527|Ensembl:ENSMUSG00000028199|Vega:OTTMUSG00000022729 +12973 crz MGI:MGI:88528 +12974 Cs MGI:MGI:88529|Ensembl:ENSMUSG00000005683 +12977 Csf1 MGI:MGI:1339753|Ensembl:ENSMUSG00000014599|Vega:OTTMUSG00000026573 +12978 Csf1r MGI:MGI:1339758|Ensembl:ENSMUSG00000024621|Vega:OTTMUSG00000014918 +12979 Csf1r-ps MGI:MGI:1339756 +12981 Csf2 MGI:MGI:1339752|Ensembl:ENSMUSG00000018916|Vega:OTTMUSG00000005663 +12982 Csf2ra MGI:MGI:1339754|Ensembl:ENSMUSG00000059326 +12983 Csf2rb MGI:MGI:1339759|Ensembl:ENSMUSG00000071713 +12984 Csf2rb2 MGI:MGI:1339760|Ensembl:ENSMUSG00000071714 +12985 Csf3 MGI:MGI:1339751|Ensembl:ENSMUSG00000038067|Vega:OTTMUSG00000006406 +12986 Csf3r MGI:MGI:1339755|Ensembl:ENSMUSG00000028859|Vega:OTTMUSG00000009297 +12988 Csk MGI:MGI:88537|Ensembl:ENSMUSG00000032312|Vega:OTTMUSG00000063203 +12990 Csn1s1 MGI:MGI:88540|Ensembl:ENSMUSG00000070702|Vega:OTTMUSG00000054070 +12991 Csn2 MGI:MGI:88541|Ensembl:ENSMUSG00000063157|Vega:OTTMUSG00000054071 +12992 Csn1s2b MGI:MGI:105312|Ensembl:ENSMUSG00000061388|Vega:OTTMUSG00000025846 +12993 Csn1s2a MGI:MGI:88542|Ensembl:ENSMUSG00000061937|Vega:OTTMUSG00000054073 +12994 Csn3 MGI:MGI:107461|Ensembl:ENSMUSG00000001622|Vega:OTTMUSG00000025838 +12995 Csnk2a1 MGI:MGI:88543|Ensembl:ENSMUSG00000074698|Vega:OTTMUSG00000015858 +12998 Csnk2a1-rs3 MGI:MGI:88546 +13000 Csnk2a2 MGI:MGI:88547|Ensembl:ENSMUSG00000046707|Vega:OTTMUSG00000061759 +13001 Csnk2b MGI:MGI:88548|Ensembl:ENSMUSG00000024387|Vega:OTTMUSG00000037175 +13002 Dnajc5 MGI:MGI:892995|Ensembl:ENSMUSG00000000826|Vega:OTTMUSG00000016739 +13003 Vcan MGI:MGI:102889|Ensembl:ENSMUSG00000021614|Vega:OTTMUSG00000033531 +13004 Ncan MGI:MGI:104694|Ensembl:ENSMUSG00000002341|Vega:OTTMUSG00000022194 +13006 Smc3 MGI:MGI:1339795|Ensembl:ENSMUSG00000024974|Vega:OTTMUSG00000024643 +13007 Csrp1 MGI:MGI:88549|Ensembl:ENSMUSG00000026421|Vega:OTTMUSG00000021802 +13008 Csrp2 MGI:MGI:1202907|Ensembl:ENSMUSG00000020186 +13009 Csrp3 MGI:MGI:1330824|Ensembl:ENSMUSG00000030470|Vega:OTTMUSG00000058985 +13010 Cst3 MGI:MGI:102519|Ensembl:ENSMUSG00000027447|Vega:OTTMUSG00000015724 +13011 Cst7 MGI:MGI:1298217|Ensembl:ENSMUSG00000068129|Vega:OTTMUSG00000015741 +13012 Cst8 MGI:MGI:107161|Ensembl:ENSMUSG00000027442|Vega:OTTMUSG00000015719 +13013 Cst9 MGI:MGI:1340053|Ensembl:ENSMUSG00000027445|Vega:OTTMUSG00000015723 +13014 Cstb MGI:MGI:109514|Ensembl:ENSMUSG00000005054 +13016 Ctbp1 MGI:MGI:1201685|Ensembl:ENSMUSG00000037373|Vega:OTTMUSG00000055360 +13017 Ctbp2 MGI:MGI:1201686|Ensembl:ENSMUSG00000030970|Vega:OTTMUSG00000036726 +13018 Ctcf MGI:MGI:109447|Ensembl:ENSMUSG00000005698|Vega:OTTMUSG00000017298 +13019 Ctf1 MGI:MGI:105115|Ensembl:ENSMUSG00000042340|Vega:OTTMUSG00000058629 +13024 Ctla2a MGI:MGI:88554|Ensembl:ENSMUSG00000044258 +13025 Ctla2b MGI:MGI:88555|Ensembl:ENSMUSG00000074874 +13026 Pcyt1a MGI:MGI:88557|Ensembl:ENSMUSG00000005615|Vega:OTTMUSG00000025786 +13030 Ctsb MGI:MGI:88561|Ensembl:ENSMUSG00000021939 +13032 Ctsc MGI:MGI:109553|Ensembl:ENSMUSG00000030560|Vega:OTTMUSG00000031137 +13033 Ctsd MGI:MGI:88562|Ensembl:ENSMUSG00000007891|Vega:OTTMUSG00000060153 +13034 Ctse MGI:MGI:107361|Ensembl:ENSMUSG00000004552|Vega:OTTMUSG00000022661 +13035 Ctsg MGI:MGI:88563|Ensembl:ENSMUSG00000040314 +13036 Ctsh MGI:MGI:107285|Ensembl:ENSMUSG00000032359|Vega:OTTMUSG00000024409 +13038 Ctsk MGI:MGI:107823|Ensembl:ENSMUSG00000028111|Vega:OTTMUSG00000053004 +13039 Ctsl MGI:MGI:88564|Ensembl:ENSMUSG00000021477 +13040 Ctss MGI:MGI:107341|Ensembl:ENSMUSG00000038642|Vega:OTTMUSG00000022029 +13041 Ctsw MGI:MGI:1338045|Ensembl:ENSMUSG00000024910 +13043 Cttn MGI:MGI:99695|Ensembl:ENSMUSG00000031078|Vega:OTTMUSG00000016455 +13046 Celf1 MGI:MGI:1342295|Ensembl:ENSMUSG00000005506|Vega:OTTMUSG00000014337 +13047 Cux1 MGI:MGI:88568|Ensembl:ENSMUSG00000029705|Vega:OTTMUSG00000040141 +13048 Cux2 MGI:MGI:107321|Ensembl:ENSMUSG00000042589|Vega:OTTMUSG00000024684 +13049 cw MGI:MGI:88569 +13050 cx MGI:MGI:88570 +13051 Cx3cr1 MGI:MGI:1333815|Ensembl:ENSMUSG00000052336|Vega:OTTMUSG00000062524 +13052 Cxadr MGI:MGI:1201679|Ensembl:ENSMUSG00000022865|Vega:OTTMUSG00000014961 +13055 cy MGI:MGI:88573 +13056 Cyb561 MGI:MGI:103253|Ensembl:ENSMUSG00000019590|Vega:OTTMUSG00000003116 +13057 Cyba MGI:MGI:1316658|Ensembl:ENSMUSG00000006519|Vega:OTTMUSG00000061846 +13058 Cybb MGI:MGI:88574|Ensembl:ENSMUSG00000015340|Vega:OTTMUSG00000016894 +13063 Cycs MGI:MGI:88578|Ensembl:ENSMUSG00000063694|Vega:OTTMUSG00000034264 +13064 Cycs-ps1 MGI:MGI:109500 +13065 Cycs-ps2 MGI:MGI:109499 +13066 Cycs-ps3 MGI:MGI:109498 +13067 Cyct MGI:MGI:88579|Ensembl:ENSMUSG00000056436|Vega:OTTMUSG00000013135 +13070 Cyp11a1 MGI:MGI:88582|Ensembl:ENSMUSG00000032323|Vega:OTTMUSG00000045946 +13072 Cyp11b2 MGI:MGI:88584|Ensembl:ENSMUSG00000022589|Vega:OTTMUSG00000035251 +13074 Cyp17a1 MGI:MGI:88586|Ensembl:ENSMUSG00000003555|Vega:OTTMUSG00000023316 +13075 Cyp19a1 MGI:MGI:88587|Ensembl:ENSMUSG00000032274|Vega:OTTMUSG00000063201 +13076 Cyp1a1 MGI:MGI:88588|Ensembl:ENSMUSG00000032315|Vega:OTTMUSG00000063205 +13077 Cyp1a2 MGI:MGI:88589|Ensembl:ENSMUSG00000032310|Vega:OTTMUSG00000063204 +13078 Cyp1b1 MGI:MGI:88590|Ensembl:ENSMUSG00000024087 +13079 Cyp21a1 MGI:MGI:88591|Ensembl:ENSMUSG00000024365|Vega:OTTMUSG00000037259 +13081 Cyp24a1 MGI:MGI:88593|Ensembl:ENSMUSG00000038567|Vega:OTTMUSG00000019774 +13082 Cyp26a1 MGI:MGI:1096359|Ensembl:ENSMUSG00000024987 +13085 Cyp2a12 MGI:MGI:105055|Ensembl:ENSMUSG00000060407|Vega:OTTMUSG00000058549 +13086 Cyp2a4 MGI:MGI:88596|Ensembl:ENSMUSG00000074254|Vega:OTTMUSG00000058416 +13087 Cyp2a5 MGI:MGI:88597|Ensembl:ENSMUSG00000005547|Vega:OTTMUSG00000036784 +13088 Cyp2b10 MGI:MGI:88598|Ensembl:ENSMUSG00000030483|Vega:OTTMUSG00000027165 +13089 Cyp2b13 MGI:MGI:88599|Ensembl:ENSMUSG00000040583|Vega:OTTMUSG00000058411 +13090 Cyp2b19 MGI:MGI:107303|Ensembl:ENSMUSG00000066704|Vega:OTTMUSG00000027196 +13094 Cyp2b9 MGI:MGI:88600|Ensembl:ENSMUSG00000040660|Vega:OTTMUSG00000037984 +13095 Cyp2c29 MGI:MGI:103238|Ensembl:ENSMUSG00000003053|Vega:OTTMUSG00000028391 +13096 Cyp2c37 MGI:MGI:1306806|Ensembl:ENSMUSG00000042248|Vega:OTTMUSG00000028289 +13097 Cyp2c38 MGI:MGI:1306819|Ensembl:ENSMUSG00000032808|Vega:OTTMUSG00000028396 +13098 Cyp2c39 MGI:MGI:1306818|Ensembl:ENSMUSG00000025003|Vega:OTTMUSG00000028407 +13099 Cyp2c40 MGI:MGI:1306815|Ensembl:ENSMUSG00000025004|Vega:OTTMUSG00000028294 +13101 Cyp2d10 MGI:MGI:88602|Ensembl:ENSMUSG00000094806 +13105 Cyp2d9 MGI:MGI:88606|Ensembl:ENSMUSG00000068086 +13106 Cyp2e1 MGI:MGI:88607|Ensembl:ENSMUSG00000025479|Vega:OTTMUSG00000060433 +13107 Cyp2f2 MGI:MGI:88608|Ensembl:ENSMUSG00000052974|Vega:OTTMUSG00000027204 +13108 Cyp2g1 MGI:MGI:109612|Ensembl:ENSMUSG00000049685|Vega:OTTMUSG00000058545 +13109 Cyp2j5 MGI:MGI:1270149|Ensembl:ENSMUSG00000052520|Vega:OTTMUSG00000007943 +13110 Cyp2j6 MGI:MGI:1270148|Ensembl:ENSMUSG00000052914|Vega:OTTMUSG00000007867 +13112 Cyp3a11 MGI:MGI:88609|Ensembl:ENSMUSG00000056035|Vega:OTTMUSG00000026077 +13113 Cyp3a13 MGI:MGI:88610|Ensembl:ENSMUSG00000029727|Vega:OTTMUSG00000022877 +13114 Cyp3a16 MGI:MGI:106099|Ensembl:ENSMUSG00000038656|Vega:OTTMUSG00000025125 +13115 Cyp27b1 MGI:MGI:1098274|Ensembl:ENSMUSG00000006724|Vega:OTTMUSG00000035227 +13116 Cyp46a1 MGI:MGI:1341877|Ensembl:ENSMUSG00000021259 +13117 Cyp4a10 MGI:MGI:88611|Ensembl:ENSMUSG00000066072|Vega:OTTMUSG00000008614 +13118 Cyp4a12b MGI:MGI:3611747|Ensembl:ENSMUSG00000078597|Vega:OTTMUSG00000008618 +13119 Cyp4a14 MGI:MGI:1096550|Ensembl:ENSMUSG00000028715|Vega:OTTMUSG00000008625 +13120 Cyp4b1 MGI:MGI:103225|Ensembl:ENSMUSG00000028713|Vega:OTTMUSG00000008682 +13121 Cyp51 MGI:MGI:106040|Ensembl:ENSMUSG00000001467|Vega:OTTMUSG00000022725 +13122 Cyp7a1 MGI:MGI:106091|Ensembl:ENSMUSG00000028240|Vega:OTTMUSG00000004315 +13123 Cyp7b1 MGI:MGI:104978|Ensembl:ENSMUSG00000039519|Vega:OTTMUSG00000051112 +13124 Cyp8b1 MGI:MGI:1338044|Ensembl:ENSMUSG00000050445|Vega:OTTMUSG00000022966 +13130 da MGI:MGI:94856 +13131 Dab1 MGI:MGI:108554|Ensembl:ENSMUSG00000028519|Vega:OTTMUSG00000008111 +13132 Dab2 MGI:MGI:109175|Ensembl:ENSMUSG00000022150|Vega:OTTMUSG00000033430 +13134 Dach1 MGI:MGI:1277991|Ensembl:ENSMUSG00000055639|Vega:OTTMUSG00000022525 +13135 Dad1 MGI:MGI:101912|Ensembl:ENSMUSG00000022174|Vega:OTTMUSG00000033740 +13136 Cd55 MGI:MGI:104850|Ensembl:ENSMUSG00000026399|Vega:OTTMUSG00000025169 +13137 Cd55b MGI:MGI:104849|Ensembl:ENSMUSG00000026401|Vega:OTTMUSG00000025172 +13138 Dag1 MGI:MGI:101864|Ensembl:ENSMUSG00000039952|Vega:OTTMUSG00000050793 +13139 Dgka MGI:MGI:102952|Ensembl:ENSMUSG00000025357 +13142 Dao MGI:MGI:94859|Ensembl:ENSMUSG00000042096|Vega:OTTMUSG00000024124 +13143 Dapk2 MGI:MGI:1341297|Ensembl:ENSMUSG00000032380|Vega:OTTMUSG00000029452 +13144 Dapk3 MGI:MGI:1203520|Ensembl:ENSMUSG00000034974 +13162 Slc6a3 MGI:MGI:94862|Ensembl:ENSMUSG00000021609 +13163 Daxx MGI:MGI:1197015|Ensembl:ENSMUSG00000002307|Vega:OTTMUSG00000037068 +13164 Dazl MGI:MGI:1342328|Ensembl:ENSMUSG00000010592 +13166 Dbh MGI:MGI:94864|Ensembl:ENSMUSG00000000889|Vega:OTTMUSG00000011838 +13167 Dbi MGI:MGI:94865|Ensembl:ENSMUSG00000026385|Vega:OTTMUSG00000021601 +13168 Dbil5 MGI:MGI:108039|Ensembl:ENSMUSG00000038057|Vega:OTTMUSG00000006224 +13169 Dbnl MGI:MGI:700006|Ensembl:ENSMUSG00000020476|Vega:OTTMUSG00000005097 +13170 Dbp MGI:MGI:94866|Ensembl:ENSMUSG00000059824|Vega:OTTMUSG00000023187 +13171 Dbt MGI:MGI:105386|Ensembl:ENSMUSG00000000340|Vega:OTTMUSG00000027084 +13172 Dbx1 MGI:MGI:94867|Ensembl:ENSMUSG00000030507|Vega:OTTMUSG00000037230 +13175 Dclk1 MGI:MGI:1330861|Ensembl:ENSMUSG00000027797|Vega:OTTMUSG00000053093 +13176 Dcc MGI:MGI:94869|Ensembl:ENSMUSG00000060534|Vega:OTTMUSG00000021996 +13177 Eci1 MGI:MGI:94871|Ensembl:ENSMUSG00000024132 +13178 Dck MGI:MGI:102726|Ensembl:ENSMUSG00000029366|Vega:OTTMUSG00000025239 +13179 Dcn MGI:MGI:94872|Ensembl:ENSMUSG00000019929 +13180 Pcbd1 MGI:MGI:94873|Ensembl:ENSMUSG00000020098 +13184 Dcpp1 MGI:MGI:105949|Ensembl:ENSMUSG00000096445 +13185 Dscr3 MGI:MGI:1206040|Ensembl:ENSMUSG00000022898|Vega:OTTMUSG00000025136 +13190 Dct MGI:MGI:102563|Ensembl:ENSMUSG00000022129 +13191 Dctn1 MGI:MGI:107745|Ensembl:ENSMUSG00000031865|Vega:OTTMUSG00000024506 +13193 Dcx MGI:MGI:1277171|Ensembl:ENSMUSG00000031285|Vega:OTTMUSG00000018842 +13194 Ddb1 MGI:MGI:1202384|Ensembl:ENSMUSG00000024740 +13195 Ddc MGI:MGI:94876|Ensembl:ENSMUSG00000020182|Vega:OTTMUSG00000005164 +13196 Asap1 MGI:MGI:1342335|Ensembl:ENSMUSG00000022377|Vega:OTTMUSG00000042047 +13197 Gadd45a MGI:MGI:107799|Ensembl:ENSMUSG00000036390|Vega:OTTMUSG00000023157 +13198 Ddit3 MGI:MGI:109247|Ensembl:ENSMUSG00000025408|Vega:OTTMUSG00000032537 +13199 Ddn MGI:MGI:108101|Ensembl:ENSMUSG00000059213 +13200 Ddost MGI:MGI:1194508|Ensembl:ENSMUSG00000028757|Vega:OTTMUSG00000009976 +13201 dds MGI:MGI:94878 +13202 Ddt MGI:MGI:1298381|Ensembl:ENSMUSG00000001666|Vega:OTTMUSG00000037564 +13204 Dhx15 MGI:MGI:1099786|Ensembl:ENSMUSG00000029169|Vega:OTTMUSG00000054564 +13205 Ddx3x MGI:MGI:103064|Ensembl:ENSMUSG00000000787|Vega:OTTMUSG00000017078 +13206 Ddx4 MGI:MGI:102670|Ensembl:ENSMUSG00000021758 +13207 Ddx5 MGI:MGI:105037|Ensembl:ENSMUSG00000020719|Vega:OTTMUSG00000003589 +13209 Ddx6 MGI:MGI:104976|Ensembl:ENSMUSG00000032097|Vega:OTTMUSG00000063351 +13211 Dhx9 MGI:MGI:108177|Ensembl:ENSMUSG00000042699|Vega:OTTMUSG00000049714 +13214 Defb1 MGI:MGI:1096878|Ensembl:ENSMUSG00000044748|Vega:OTTMUSG00000019983 +13215 Defb2 MGI:MGI:1338754|Ensembl:ENSMUSG00000006570|Vega:OTTMUSG00000020785 +13216 Defa1 MGI:MGI:94880 +13218 Defa29 MGI:MGI:94881|Ensembl:ENSMUSG00000074437|Vega:OTTMUSG00000019792 +13219 Defa-rs10 MGI:MGI:102516 +13221 Defa-rs12 MGI:MGI:102514 +13222 Defa-rs2 MGI:MGI:99592 +13223 Defa-rs4 MGI:MGI:102512 +13226 Defa31 MGI:MGI:102509|Ensembl:ENSMUSG00000074442|Vega:OTTMUSG00000019762 +13229 Defa10 MGI:MGI:99591 +13230 Defa11 MGI:MGI:99590 +13231 Defa12 MGI:MGI:99589 +13232 Defa13 MGI:MGI:99588 +13233 Defa14 MGI:MGI:99587 +13234 Defa15 MGI:MGI:99586 +13235 Defa16 MGI:MGI:99585 +13236 Defa25 MGI:MGI:3630385|Ensembl:ENSMUSG00000094687|Vega:OTTMUSG00000019700 +13237 Defa3 MGI:MGI:94883|Ensembl:ENSMUSG00000074440|Vega:OTTMUSG00000019782 +13238 Defa4 MGI:MGI:99584 +13239 Defa5 MGI:MGI:99583|Ensembl:ENSMUSG00000074439|Vega:OTTMUSG00000019785 +13240 Defa6 MGI:MGI:99582 +13241 Defa7 MGI:MGI:99581 +13242 Defa8 MGI:MGI:99580 +13243 Defa9 MGI:MGI:99579 +13244 Degs1 MGI:MGI:1097711|Ensembl:ENSMUSG00000038633|Vega:OTTMUSG00000021622 +13249 Del(1)3H MGI:MGI:103583 +13250 Del(1)42H MGI:MGI:103587 +13251 Del(1)55H MGI:MGI:103588 +13252 Del(1)57H MGI:MGI:103589 +13253 Del(1)58H MGI:MGI:103590 +13254 Del(1)66H MGI:MGI:103591 +13255 Del(1)6H MGI:MGI:103584 +13256 Del(1)70H MGI:MGI:103592 +13257 Del(10)12H MGI:MGI:104048 +13258 Del(10)13H MGI:MGI:104049 +13259 Del(10)1H MGI:MGI:104044 +13260 Del(10)21H MGI:MGI:104050 +13261 Del(10)2H MGI:MGI:104045 +13262 Del(10)41H MGI:MGI:104051 +13263 Del(10)65H MGI:MGI:104052 +13264 Del(10)69H MGI:MGI:104053 +13265 Del(10)8H MGI:MGI:104046 +13266 Del(10)9H MGI:MGI:104047 +13267 Del(12)75H MGI:MGI:108168 +13268 Del(13)36H MGI:MGI:104137 +13269 Del(13)52H MGI:MGI:104138 +13270 Del(13)81H MGI:MGI:1314641 +13271 Del(14)10H MGI:MGI:104149 +13272 Del(14)14H MGI:MGI:104150 +13273 Del(14)15H MGI:MGI:104151 +13274 Del(14)19H MGI:MGI:108169 +13275 Del(14)22H MGI:MGI:104152 +13276 Del(14)23H MGI:MGI:104153 +13277 Del(14)28H MGI:MGI:104154 +13278 Del(14)29H MGI:MGI:104155 +13279 Del(14)30H MGI:MGI:104156 +13280 Del(14)31H MGI:MGI:104157 +13281 Del(14)32H MGI:MGI:104158 +13282 Del(14)38H MGI:MGI:104159 +13283 Del(14)39H MGI:MGI:104160 +13284 Del(14)40H MGI:MGI:104161 +13285 Del(14)45H MGI:MGI:104162 +13286 Del(14)46H MGI:MGI:104163 +13287 Del(14)5H MGI:MGI:108170 +13288 Del(14)60H MGI:MGI:104164 +13291 Del(16)34H MGI:MGI:104195 +13292 Del(16)51H MGI:MGI:104196 +13293 Del(17)11H MGI:MGI:104223 +13294 Del(17)18H MGI:MGI:104224 +13295 Del(17)1t-d MGI:MGI:105948 +13296 Del(17)1t-p MGI:MGI:1196948 +13297 Del(17)T<7J>1J MGI:MGI:1203518 +13298 Del(18)20H MGI:MGI:104234 +13299 Del(19)Tg8052Mm MGI:MGI:104236 +13300 Del(2)35H MGI:MGI:103664 +13301 Del(2)59H MGI:MGI:103665 +13302 Del(2)Usc1 MGI:MGI:107467 +13303 Del(3)1Rn MGI:MGI:103735 +13304 Del(3)48H MGI:MGI:103736 +13305 Del(3)54H MGI:MGI:103737 +13306 Del(3)61H MGI:MGI:103738 +13307 Del(3)64H MGI:MGI:103739 +13308 Del(3)76H MGI:MGI:108167 +13309 Del(4)16H MGI:MGI:103775 +13310 Del(4)17H MGI:MGI:103776 +13311 Del(4)53H MGI:MGI:103777 +13312 Del(5)25H MGI:MGI:103828 +13313 Del(5)43H MGI:MGI:103829 +13314 Del(5)47H MGI:MGI:103830 +13315 Del(5)68H MGI:MGI:103831 +13316 Del(5)73H MGI:MGI:108164 +13317 Del(6)26H MGI:MGI:103886 +13318 Del(7)Tyr MGI:MGI:103934 +13319 Del(7)49H MGI:MGI:103935 +13320 Del(7)56H MGI:MGI:103936 +13321 Del(7)Tyr-p MGI:MGI:1337023 +13322 Del(8)44H MGI:MGI:103982 +13323 Del(8)50H MGI:MGI:103983 +13324 Del(8)62H MGI:MGI:103984 +13325 Del(8)71H MGI:MGI:103985 +13326 Del(8)72H MGI:MGI:108165 +13327 Del(8)74H MGI:MGI:108166 +13328 Del(8A4-B3)7H MGI:MGI:4430113 +13329 Del(9)4H MGI:MGI:104014 +13330 Del(9)63H MGI:MGI:104015 +13331 Del(Y)2Psb MGI:MGI:104285 +13332 Del(Y)1Ct-d MGI:MGI:1314654 +13333 Del(Y)1Ct-p MGI:MGI:1314657 +13334 Del(Y)B10.BR-Y/Ms MGI:MGI:104284 +13335 Del(Y)Sxrb-d MGI:MGI:1314650 +13336 Del(Y)Sxrb-p MGI:MGI:1314648 +13340 Slc29a2 MGI:MGI:1345278|Ensembl:ENSMUSG00000024891 +13345 Twist2 MGI:MGI:104685|Ensembl:ENSMUSG00000007805|Vega:OTTMUSG00000021957 +13346 Des MGI:MGI:94885|Ensembl:ENSMUSG00000026208|Vega:OTTMUSG00000019416 +13347 Dffa MGI:MGI:1196227|Ensembl:ENSMUSG00000028974|Vega:OTTMUSG00000010959 +13349 Ackr1 MGI:MGI:1097689|Ensembl:ENSMUSG00000037872|Vega:OTTMUSG00000050197 +13350 Dgat1 MGI:MGI:1333825|Ensembl:ENSMUSG00000022555|Vega:OTTMUSG00000034893 +13353 Dgcr6 MGI:MGI:1202877|Ensembl:ENSMUSG00000003531|Vega:OTTMUSG00000028179 +13356 Dgcr2 MGI:MGI:892866|Ensembl:ENSMUSG00000003166|Ensembl:ENSMUSG00000092470|Vega:OTTMUSG00000028898|Vega:OTTMUSG00000037698 +13358 Slc25a1 MGI:MGI:1345283|Ensembl:ENSMUSG00000003528|Vega:OTTMUSG00000026786 +13360 Dhcr7 MGI:MGI:1298378|Ensembl:ENSMUSG00000058454|Vega:OTTMUSG00000025933 +13361 Dhfr MGI:MGI:94890|Ensembl:ENSMUSG00000021707 +13363 Dhh MGI:MGI:94891|Ensembl:ENSMUSG00000023000 +13364 di MGI:MGI:94892 +13367 Diaph1 MGI:MGI:1194490|Ensembl:ENSMUSG00000024456|Vega:OTTMUSG00000021095 +13368 Dffb MGI:MGI:1196287|Ensembl:ENSMUSG00000029027|Vega:OTTMUSG00000010511 +13370 Dio1 MGI:MGI:94896|Ensembl:ENSMUSG00000034785|Vega:OTTMUSG00000008706 +13371 Dio2 MGI:MGI:1338833|Ensembl:ENSMUSG00000007682 +13380 Dkk1 MGI:MGI:1329040|Ensembl:ENSMUSG00000024868|Vega:OTTMUSG00000020350 +13382 Dld MGI:MGI:107450|Ensembl:ENSMUSG00000020664 +13383 Dlg1 MGI:MGI:107231|Ensembl:ENSMUSG00000022770|Vega:OTTMUSG00000016269 +13384 Mpp3 MGI:MGI:1328354|Ensembl:ENSMUSG00000052373|Vega:OTTMUSG00000002318 +13385 Dlg4 MGI:MGI:1277959|Ensembl:ENSMUSG00000020886|Vega:OTTMUSG00000006024 +13386 Dlk1 MGI:MGI:94900|Ensembl:ENSMUSG00000040856|Vega:OTTMUSG00000022851 +13388 Dll1 MGI:MGI:104659|Ensembl:ENSMUSG00000014773|Vega:OTTMUSG00000021037 +13389 Dll3 MGI:MGI:1096877|Ensembl:ENSMUSG00000003436|Vega:OTTMUSG00000022517 +13390 Dlx1 MGI:MGI:94901|Ensembl:ENSMUSG00000041911|Vega:OTTMUSG00000013200 +13392 Dlx2 MGI:MGI:94902|Ensembl:ENSMUSG00000023391|Vega:OTTMUSG00000013199 +13393 Dlx3 MGI:MGI:94903|Ensembl:ENSMUSG00000001510|Vega:OTTMUSG00000001614 +13394 Dlx4 MGI:MGI:94904|Ensembl:ENSMUSG00000020871|Vega:OTTMUSG00000001615 +13395 Dlx5 MGI:MGI:101926|Ensembl:ENSMUSG00000029755|Vega:OTTMUSG00000021177 +13396 Dlx6 MGI:MGI:101927|Ensembl:ENSMUSG00000029754|Vega:OTTMUSG00000034244 +13397 Dlx6os2 MGI:MGI:1195963|Ensembl:ENSMUSG00000094868 +13399 dm MGI:MGI:94905 +13400 Dmpk MGI:MGI:94906|Ensembl:ENSMUSG00000030409|Vega:OTTMUSG00000024656 +13401 Dmwd MGI:MGI:94907|Ensembl:ENSMUSG00000030410|Vega:OTTMUSG00000022947 +13404 Dmc1 MGI:MGI:105393|Ensembl:ENSMUSG00000022429 +13405 Dmd MGI:MGI:94909|Ensembl:ENSMUSG00000045103|Vega:OTTMUSG00000017938 +13406 Dmp1 MGI:MGI:94910|Ensembl:ENSMUSG00000029307|Vega:OTTMUSG00000053772 +13409 Tmc1 MGI:MGI:2151016|Ensembl:ENSMUSG00000024749 +13411 Dnah11 MGI:MGI:1100864|Ensembl:ENSMUSG00000018581|Vega:OTTMUSG00000040132 +13417 Dnah8 MGI:MGI:107714|Ensembl:ENSMUSG00000033826 +13418 Dnajc1 MGI:MGI:103268|Ensembl:ENSMUSG00000026740|Vega:OTTMUSG00000011538 +13419 Dnase1 MGI:MGI:103157|Ensembl:ENSMUSG00000005980|Vega:OTTMUSG00000027161 +13421 Dnase1l3 MGI:MGI:1314633|Ensembl:ENSMUSG00000025279|Vega:OTTMUSG00000024054 +13423 Dnase2a MGI:MGI:1329019|Ensembl:ENSMUSG00000003812|Vega:OTTMUSG00000022266 +13424 Dync1h1 MGI:MGI:103147|Ensembl:ENSMUSG00000018707|Vega:OTTMUSG00000036080 +13426 Dync1i1 MGI:MGI:107743|Ensembl:ENSMUSG00000029757|Vega:OTTMUSG00000023538 +13427 Dync1i2 MGI:MGI:107750|Ensembl:ENSMUSG00000027012|Vega:OTTMUSG00000013157 +13429 Dnm1 MGI:MGI:107384|Ensembl:ENSMUSG00000026825|Vega:OTTMUSG00000012945 +13430 Dnm2 MGI:MGI:109547|Ensembl:ENSMUSG00000033335|Vega:OTTMUSG00000038087 +13433 Dnmt1 MGI:MGI:94912|Ensembl:ENSMUSG00000004099|Vega:OTTMUSG00000063003 +13434 Trdmt1 MGI:MGI:1274787|Ensembl:ENSMUSG00000026723|Vega:OTTMUSG00000011229 +13435 Dnmt3a MGI:MGI:1261827|Ensembl:ENSMUSG00000020661|Vega:OTTMUSG00000037610 +13436 Dnmt3b MGI:MGI:1261819|Ensembl:ENSMUSG00000027478|Vega:OTTMUSG00000016775 +13437 Dnpep MGI:MGI:1278328|Ensembl:ENSMUSG00000026209|Vega:OTTMUSG00000048821 +13445 Cdk2ap1 MGI:MGI:1202069|Ensembl:ENSMUSG00000029394|Vega:OTTMUSG00000024438 +13446 Doc2a MGI:MGI:109446|Ensembl:ENSMUSG00000052301|Vega:OTTMUSG00000023358 +13447 Doc2b MGI:MGI:1100497|Ensembl:ENSMUSG00000020848|Vega:OTTMUSG00000006220 +13448 Dok1 MGI:MGI:893587|Ensembl:ENSMUSG00000068335|Vega:OTTMUSG00000023337 +13449 Dok2 MGI:MGI:1332623|Ensembl:ENSMUSG00000022102|Vega:OTTMUSG00000035182 +13450 dp MGI:MGI:94915 +13451 Is(13;1)4H MGI:MGI:103594 +13452 Dp(1)6H MGI:MGI:103593 +13453 Dp(12)7H MGI:MGI:104124 +13454 Dp(12)9H MGI:MGI:104125 +13455 Dp(13)17H MGI:MGI:104139 +13456 Dp(14)18H MGI:MGI:104167 +13457 Dp(14)2H MGI:MGI:104166 +13458 Dp(15)5H MGI:MGI:104179 +13459 Dp(16)15H MGI:MGI:104198 +13460 Dp(16)8H MGI:MGI:104197 +13461 Dp(17)1 MGI:MGI:105947 +13462 Dp(17)1t MGI:MGI:105946 +13463 Dp(18)4H MGI:MGI:104235 +13464 Dp(18Hc)1H MGI:MGI:104337 +13465 Dp(2)11H MGI:MGI:103666 +13466 Dp(3)10H MGI:MGI:103734 +13469 Dp(7)19H MGI:MGI:103932 +13470 Dp(7)1H MGI:MGI:103930 +13471 Dp(7)1Rl MGI:MGI:103933 +13472 Dp(9)12H MGI:MGI:104017 +13473 Dp(9)14H MGI:MGI:104018 +13474 Dp(9)3H MGI:MGI:104016 +13475 Dp(Hc18) MGI:MGI:94916 +13476 Reep5 MGI:MGI:1270152|Ensembl:ENSMUSG00000005873 +13478 Dpagt1 MGI:MGI:1196396|Ensembl:ENSMUSG00000032123|Vega:OTTMUSG00000063247 +13479 Dpep1 MGI:MGI:94917|Ensembl:ENSMUSG00000019278|Vega:OTTMUSG00000061883 +13480 Dpm1 MGI:MGI:1330239|Ensembl:ENSMUSG00000078919|Ensembl:ENSMUSG00000093752|Vega:OTTMUSG00000016047|Vega:OTTMUSG00000040161 +13481 Dpm2 MGI:MGI:1330238|Ensembl:ENSMUSG00000026810|Vega:OTTMUSG00000011991 +13482 Dpp4 MGI:MGI:94919|Ensembl:ENSMUSG00000035000|Vega:OTTMUSG00000012759 +13483 Dpp6 MGI:MGI:94921|Ensembl:ENSMUSG00000061576|Vega:OTTMUSG00000029575 +13484 dmpy MGI:MGI:94922 +13486 Dr1 MGI:MGI:1100515|Ensembl:ENSMUSG00000029265|Vega:OTTMUSG00000028923 +13487 Slc26a3 MGI:MGI:107181|Ensembl:ENSMUSG00000001225|Vega:OTTMUSG00000035459 +13488 Drd1 MGI:MGI:99578|Ensembl:ENSMUSG00000021478 +13489 Drd2 MGI:MGI:94924|Ensembl:ENSMUSG00000032259|Vega:OTTMUSG00000063016 +13490 Drd3 MGI:MGI:94925|Ensembl:ENSMUSG00000022705 +13491 Drd4 MGI:MGI:94926|Ensembl:ENSMUSG00000025496|Vega:OTTMUSG00000060260 +13492 Drd5 MGI:MGI:94927|Ensembl:ENSMUSG00000039358|Vega:OTTMUSG00000056102 +13494 Drg1 MGI:MGI:1343297|Ensembl:ENSMUSG00000020457|Vega:OTTMUSG00000000765 +13495 Drg2 MGI:MGI:1342307|Ensembl:ENSMUSG00000020537|Vega:OTTMUSG00000005817 +13496 Arid3a MGI:MGI:1328360|Ensembl:ENSMUSG00000019564|Vega:OTTMUSG00000023712 +13497 Drp2 MGI:MGI:107432|Ensembl:ENSMUSG00000000223|Vega:OTTMUSG00000019226 +13498 Atn1 MGI:MGI:104725|Ensembl:ENSMUSG00000004263|Ensembl:ENSMUSG00000107478|Vega:OTTMUSG00000023122|Vega:OTTMUSG00000056673 +13499 Drr1 MGI:MGI:1298401 +13502 Drr2 MGI:MGI:1298402 +13505 Dsc1 MGI:MGI:109173|Ensembl:ENSMUSG00000044322 +13506 Dsc2 MGI:MGI:103221|Ensembl:ENSMUSG00000024331|Vega:OTTMUSG00000026419 +13507 Dsc3 MGI:MGI:1194993|Ensembl:ENSMUSG00000059898 +13508 Dscam MGI:MGI:1196281|Ensembl:ENSMUSG00000050272|Vega:OTTMUSG00000017081 +13509 dscb MGI:MGI:107510 +13510 Dsg1a MGI:MGI:94930|Ensembl:ENSMUSG00000069441|Vega:OTTMUSG00000016312 +13511 Dsg2 MGI:MGI:1196466|Ensembl:ENSMUSG00000044393|Vega:OTTMUSG00000030073 +13512 Dsg3 MGI:MGI:99499|Ensembl:ENSMUSG00000056632 +13516 Epyc MGI:MGI:107942|Ensembl:ENSMUSG00000019936|Vega:OTTMUSG00000024039 +13518 Dst MGI:MGI:104627|Ensembl:ENSMUSG00000026131|Vega:OTTMUSG00000044431 +13521 Slc26a2 MGI:MGI:892977|Ensembl:ENSMUSG00000034320|Vega:OTTMUSG00000032643 +13522 Adam28 MGI:MGI:105988|Ensembl:ENSMUSG00000014725 +13524 Adam18 MGI:MGI:105986|Ensembl:ENSMUSG00000031552|Vega:OTTMUSG00000025319 +13525 Adam26a MGI:MGI:105985|Ensembl:ENSMUSG00000048516|Vega:OTTMUSG00000061171 +13526 Adam24 MGI:MGI:105984|Ensembl:ENSMUSG00000046723|Vega:OTTMUSG00000061116 +13527 Dtna MGI:MGI:106039|Ensembl:ENSMUSG00000024302 +13528 Dtnb MGI:MGI:1203728|Ensembl:ENSMUSG00000071454|Vega:OTTMUSG00000037895 +13529 Prl8a2 MGI:MGI:894281|Ensembl:ENSMUSG00000018259|Vega:OTTMUSG00000000640 +13531 Usp17la MGI:MGI:107699|Ensembl:ENSMUSG00000054568|Vega:OTTMUSG00000027330 +13532 Usp17lc MGI:MGI:107698|Ensembl:ENSMUSG00000058976 +13535 dup MGI:MGI:94936 +13537 Dusp2 MGI:MGI:101911|Ensembl:ENSMUSG00000027368|Vega:OTTMUSG00000016021 +13542 Dvl1 MGI:MGI:94941|Ensembl:ENSMUSG00000029071|Vega:OTTMUSG00000010890 +13543 Dvl2 MGI:MGI:106613|Ensembl:ENSMUSG00000020888|Vega:OTTMUSG00000006016 +13544 Dvl3 MGI:MGI:108100|Ensembl:ENSMUSG00000003233|Vega:OTTMUSG00000035778 +13548 Dyrk1a MGI:MGI:1330299|Ensembl:ENSMUSG00000022897|Vega:OTTMUSG00000028435 +13549 Dyrk1b MGI:MGI:1330302|Ensembl:ENSMUSG00000002409|Vega:OTTMUSG00000037983 +13555 E2f1 MGI:MGI:101941|Ensembl:ENSMUSG00000027490|Vega:OTTMUSG00000015917 +13557 E2f3 MGI:MGI:1096340|Ensembl:ENSMUSG00000016477|Vega:OTTMUSG00000000738 +13559 E2f5 MGI:MGI:105091|Ensembl:ENSMUSG00000027552|Vega:OTTMUSG00000051204 +13560 E4f1 MGI:MGI:109530|Ensembl:ENSMUSG00000024137 +13586 Ear1 MGI:MGI:108021|Ensembl:ENSMUSG00000072601|Vega:OTTMUSG00000034642 +13587 Ear2 MGI:MGI:108020|Ensembl:ENSMUSG00000072596|Vega:OTTMUSG00000034641 +13589 Mapre1 MGI:MGI:891995|Ensembl:ENSMUSG00000027479|Vega:OTTMUSG00000016820 +13590 Lefty1 MGI:MGI:107405|Ensembl:ENSMUSG00000038793|Vega:OTTMUSG00000021473 +13591 Ebf1 MGI:MGI:95275|Ensembl:ENSMUSG00000057098|Vega:OTTMUSG00000005474 +13592 Ebf2 MGI:MGI:894332|Ensembl:ENSMUSG00000022053|Vega:OTTMUSG00000040034 +13593 Ebf3 MGI:MGI:894289|Ensembl:ENSMUSG00000010476|Vega:OTTMUSG00000060308 +13594 ebo MGI:MGI:107466 +13595 Ebp MGI:MGI:107822|Ensembl:ENSMUSG00000031168|Vega:OTTMUSG00000018119 +13599 Ecel1 MGI:MGI:1343461|Ensembl:ENSMUSG00000026247|Vega:OTTMUSG00000034823 +13600 Eclb MGI:MGI:95279 +13601 Ecm1 MGI:MGI:103060|Ensembl:ENSMUSG00000028108|Vega:OTTMUSG00000030311 +13602 Sparcl1 MGI:MGI:108110|Ensembl:ENSMUSG00000029309|Vega:OTTMUSG00000053770 +13603 Opn3 MGI:MGI:1338022|Ensembl:ENSMUSG00000026525|Vega:OTTMUSG00000021478 +13604 Ecs MGI:MGI:95280 +13605 Ect2 MGI:MGI:95281|Ensembl:ENSMUSG00000027699|Vega:OTTMUSG00000021265 +13607 Eda MGI:MGI:1195272|Ensembl:ENSMUSG00000059327|Vega:OTTMUSG00000018058 +13608 Edar MGI:MGI:1343498|Ensembl:ENSMUSG00000003227|Vega:OTTMUSG00000025045 +13609 S1pr1 MGI:MGI:1096355|Ensembl:ENSMUSG00000045092|Vega:OTTMUSG00000054437 +13610 S1pr3 MGI:MGI:1339365|Ensembl:ENSMUSG00000067586 +13611 S1pr4 MGI:MGI:1333809|Ensembl:ENSMUSG00000044199 +13612 Edil3 MGI:MGI:1329025|Ensembl:ENSMUSG00000034488|Vega:OTTMUSG00000027759 +13614 Edn1 MGI:MGI:95283|Ensembl:ENSMUSG00000021367 +13615 Edn2 MGI:MGI:95284|Ensembl:ENSMUSG00000028635|Vega:OTTMUSG00000008781 +13616 Edn3 MGI:MGI:95285|Ensembl:ENSMUSG00000027524|Vega:OTTMUSG00000016515 +13617 Ednra MGI:MGI:105923|Ensembl:ENSMUSG00000031616|Vega:OTTMUSG00000024406 +13618 Ednrb MGI:MGI:102720|Ensembl:ENSMUSG00000022122 +13619 Phc1 MGI:MGI:103248|Ensembl:ENSMUSG00000040669|Vega:OTTMUSG00000034663 +13623 Edv MGI:MGI:99933 +13626 Eed MGI:MGI:95286|Ensembl:ENSMUSG00000030619|Vega:OTTMUSG00000021134 +13627 Eef1a1 MGI:MGI:1096881|Ensembl:ENSMUSG00000037742|Vega:OTTMUSG00000019692 +13628 Eef1a2 MGI:MGI:1096317|Ensembl:ENSMUSG00000016349|Vega:OTTMUSG00000016559 +13629 Eef2 MGI:MGI:95288|Ensembl:ENSMUSG00000034994 +13631 Eef2k MGI:MGI:1195261|Ensembl:ENSMUSG00000035064|Vega:OTTMUSG00000026126 +13636 Efna1 MGI:MGI:103236|Ensembl:ENSMUSG00000027954|Vega:OTTMUSG00000028819 +13637 Efna2 MGI:MGI:102707|Ensembl:ENSMUSG00000003070|Vega:OTTMUSG00000000009 +13638 Efna3 MGI:MGI:106644|Ensembl:ENSMUSG00000028039|Vega:OTTMUSG00000028865 +13639 Efna4 MGI:MGI:106643|Ensembl:ENSMUSG00000028040|Vega:OTTMUSG00000022077 +13640 Efna5 MGI:MGI:107444|Ensembl:ENSMUSG00000048915|Vega:OTTMUSG00000030233 +13641 Efnb1 MGI:MGI:102708|Ensembl:ENSMUSG00000031217|Vega:OTTMUSG00000018065 +13642 Efnb2 MGI:MGI:105097|Ensembl:ENSMUSG00000001300|Vega:OTTMUSG00000022160 +13643 Efnb3 MGI:MGI:109196|Ensembl:ENSMUSG00000003934|Vega:OTTMUSG00000005987 +13644 Efs MGI:MGI:105311|Ensembl:ENSMUSG00000022203 +13645 Egf MGI:MGI:95290|Ensembl:ENSMUSG00000028017|Vega:OTTMUSG00000054128 +13646 Klk1b22 MGI:MGI:95291|Ensembl:ENSMUSG00000060177|Vega:OTTMUSG00000027243 +13647 Egfbp2 MGI:MGI:95292 +13648 Klk1b9 MGI:MGI:95293|Ensembl:ENSMUSG00000059042|Vega:OTTMUSG00000027239 +13649 Egfr MGI:MGI:95294|Ensembl:ENSMUSG00000020122|Vega:OTTMUSG00000005185 +13650 Rhbdf1 MGI:MGI:104328|Ensembl:ENSMUSG00000020282|Vega:OTTMUSG00000005370 +13653 Egr1 MGI:MGI:95295|Ensembl:ENSMUSG00000038418|Vega:OTTMUSG00000021064 +13654 Egr2 MGI:MGI:95296|Ensembl:ENSMUSG00000037868|Vega:OTTMUSG00000033571 +13655 Egr3 MGI:MGI:1306780|Ensembl:ENSMUSG00000033730 +13656 Egr4 MGI:MGI:99252|Ensembl:ENSMUSG00000071341|Vega:OTTMUSG00000055994 +13660 Ehd1 MGI:MGI:1341878|Ensembl:ENSMUSG00000024772|Vega:OTTMUSG00000018621 +13661 Ehf MGI:MGI:1270840|Ensembl:ENSMUSG00000012350|Vega:OTTMUSG00000014852 +13663 Ei24 MGI:MGI:108090|Ensembl:ENSMUSG00000062762|Vega:OTTMUSG00000044747 +13664 Eif1a MGI:MGI:95298|Ensembl:ENSMUSG00000057561 +13665 Eif2s1 MGI:MGI:95299|Ensembl:ENSMUSG00000021116|Vega:OTTMUSG00000031427 +13666 Eif2ak3 MGI:MGI:1341830|Ensembl:ENSMUSG00000031668|Vega:OTTMUSG00000031093 +13667 Eif2b4 MGI:MGI:95300|Ensembl:ENSMUSG00000029145|Vega:OTTMUSG00000022484 +13669 Eif3a MGI:MGI:95301|Ensembl:ENSMUSG00000024991 +13674 Eif4a-ps4 MGI:MGI:1195958 +13680 Ddx19a MGI:MGI:99526|Ensembl:ENSMUSG00000015023|Vega:OTTMUSG00000031897 +13681 Eif4a1 MGI:MGI:95303|Ensembl:ENSMUSG00000059796|Vega:OTTMUSG00000005995 +13682 Eif4a2 MGI:MGI:106906|Ensembl:ENSMUSG00000022884|Vega:OTTMUSG00000025917 +13684 Eif4e MGI:MGI:95305|Ensembl:ENSMUSG00000028156|Vega:OTTMUSG00000052912 +13685 Eif4ebp1 MGI:MGI:103267|Ensembl:ENSMUSG00000031490|Vega:OTTMUSG00000061031 +13688 Eif4ebp2 MGI:MGI:109198|Ensembl:ENSMUSG00000020091 +13690 Eif4g2 MGI:MGI:109207|Ensembl:ENSMUSG00000005610|Vega:OTTMUSG00000035134 +13706 Cela2a MGI:MGI:95316|Ensembl:ENSMUSG00000058579|Vega:OTTMUSG00000009988 +13708 elap MGI:MGI:105916 +13709 Elf1 MGI:MGI:107180|Ensembl:ENSMUSG00000036461 +13710 Elf3 MGI:MGI:1101781|Ensembl:ENSMUSG00000003051|Vega:OTTMUSG00000049800 +13711 Elf5 MGI:MGI:1335079|Ensembl:ENSMUSG00000027186|Vega:OTTMUSG00000014860 +13712 Elk1 MGI:MGI:101833|Ensembl:ENSMUSG00000009406|Vega:OTTMUSG00000017185 +13713 Elk3 MGI:MGI:101762|Ensembl:ENSMUSG00000008398|Vega:OTTMUSG00000033471 +13714 Elk4 MGI:MGI:102853|Ensembl:ENSMUSG00000026436|Vega:OTTMUSG00000024989 +13716 Ell MGI:MGI:109377|Ensembl:ENSMUSG00000070002|Vega:OTTMUSG00000061444 +13717 Eln MGI:MGI:95317|Ensembl:ENSMUSG00000029675|Vega:OTTMUSG00000055763 +13722 Aimp1 MGI:MGI:102774|Ensembl:ENSMUSG00000028029|Vega:OTTMUSG00000054910 +13723 Emb MGI:MGI:95321|Ensembl:ENSMUSG00000021728|Vega:OTTMUSG00000015373 +13726 Emd MGI:MGI:108117|Ensembl:ENSMUSG00000001964|Vega:OTTMUSG00000017684 +13728 Mark2 MGI:MGI:99638|Ensembl:ENSMUSG00000024969|Vega:OTTMUSG00000035747 +13730 Emp1 MGI:MGI:107941|Ensembl:ENSMUSG00000030208|Vega:OTTMUSG00000021171 +13731 Emp2 MGI:MGI:1098726|Ensembl:ENSMUSG00000022505|Vega:OTTMUSG00000035738 +13732 Emp3 MGI:MGI:1098729|Ensembl:ENSMUSG00000040212|Vega:OTTMUSG00000059934 +13733 Adgre1 MGI:MGI:106912|Ensembl:ENSMUSG00000004730 +13796 Emx1 MGI:MGI:95387|Ensembl:ENSMUSG00000033726|Vega:OTTMUSG00000037267 +13797 Emx2 MGI:MGI:95388|Ensembl:ENSMUSG00000043969|Vega:OTTMUSG00000037270 +13798 En1 MGI:MGI:95389|Ensembl:ENSMUSG00000058665|Vega:OTTMUSG00000037271 +13799 En2 MGI:MGI:95390|Ensembl:ENSMUSG00000039095|Vega:OTTMUSG00000037277 +13800 Enah MGI:MGI:108360|Ensembl:ENSMUSG00000022995|Vega:OTTMUSG00000050713 +13801 Enam MGI:MGI:1333772|Ensembl:ENSMUSG00000029286|Vega:OTTMUSG00000055388 +13803 Enc1 MGI:MGI:109610|Ensembl:ENSMUSG00000041773 +13804 Endog MGI:MGI:1261433|Ensembl:ENSMUSG00000015337|Vega:OTTMUSG00000016745 +13805 Eng MGI:MGI:95392|Ensembl:ENSMUSG00000026814|Vega:OTTMUSG00000011981 +13806 Eno1 MGI:MGI:95393|Ensembl:ENSMUSG00000063524|Vega:OTTMUSG00000010390 +13807 Eno2 MGI:MGI:95394|Ensembl:ENSMUSG00000004267|Vega:OTTMUSG00000022240 +13808 Eno3 MGI:MGI:95395|Ensembl:ENSMUSG00000060600|Vega:OTTMUSG00000006071 +13809 Enpep MGI:MGI:106645|Ensembl:ENSMUSG00000028024|Vega:OTTMUSG00000036814 +13812 eob MGI:MGI:95397 +13813 Eomes MGI:MGI:1201683|Ensembl:ENSMUSG00000032446|Vega:OTTMUSG00000021058 +13819 Epas1 MGI:MGI:109169|Ensembl:ENSMUSG00000024140 +13821 Epb41l1 MGI:MGI:103010|Ensembl:ENSMUSG00000027624|Vega:OTTMUSG00000015876 +13822 Epb41l2 MGI:MGI:103009|Ensembl:ENSMUSG00000019978 +13823 Epb41l3 MGI:MGI:103008|Ensembl:ENSMUSG00000024044|Vega:OTTMUSG00000060066 +13824 Epb41l4a MGI:MGI:103007|Ensembl:ENSMUSG00000024376 +13828 Epb42 MGI:MGI:95402|Ensembl:ENSMUSG00000023216|Vega:OTTMUSG00000015964 +13829 Dmtn MGI:MGI:99670|Ensembl:ENSMUSG00000022099 +13830 Stom MGI:MGI:95403|Ensembl:ENSMUSG00000026880|Vega:OTTMUSG00000012089 +13831 Epc1 MGI:MGI:1278322|Ensembl:ENSMUSG00000024240|Vega:OTTMUSG00000017262 +13834 epf MGI:MGI:95404 +13835 Epha1 MGI:MGI:107381|Ensembl:ENSMUSG00000029859|Vega:OTTMUSG00000057494 +13836 Epha2 MGI:MGI:95278|Ensembl:ENSMUSG00000006445|Vega:OTTMUSG00000010200 +13837 Epha3 MGI:MGI:99612|Ensembl:ENSMUSG00000052504 +13838 Epha4 MGI:MGI:98277|Ensembl:ENSMUSG00000026235|Vega:OTTMUSG00000047778 +13839 Epha5 MGI:MGI:99654|Ensembl:ENSMUSG00000029245|Vega:OTTMUSG00000021427 +13840 Epha6 MGI:MGI:108034|Ensembl:ENSMUSG00000055540|Vega:OTTMUSG00000026143 +13841 Epha7 MGI:MGI:95276|Ensembl:ENSMUSG00000028289|Vega:OTTMUSG00000004869 +13842 Epha8 MGI:MGI:109378|Ensembl:ENSMUSG00000028661|Vega:OTTMUSG00000009825 +13844 Ephb2 MGI:MGI:99611|Ensembl:ENSMUSG00000028664|Vega:OTTMUSG00000009767 +13845 Ephb3 MGI:MGI:104770|Ensembl:ENSMUSG00000005958|Vega:OTTMUSG00000035120 +13846 Ephb4 MGI:MGI:104757|Ensembl:ENSMUSG00000029710|Vega:OTTMUSG00000021937 +13848 Ephb6 MGI:MGI:1096338|Ensembl:ENSMUSG00000029869|Vega:OTTMUSG00000035976 +13849 Ephx1 MGI:MGI:95405|Ensembl:ENSMUSG00000038776|Vega:OTTMUSG00000021983 +13850 Ephx2 MGI:MGI:99500|Ensembl:ENSMUSG00000022040 +13851 epi MGI:MGI:95406 +13852 Stx2 MGI:MGI:108059|Ensembl:ENSMUSG00000029428|Vega:OTTMUSG00000027708 +13853 Epm2a MGI:MGI:1341085|Ensembl:ENSMUSG00000055493|Vega:OTTMUSG00000031733 +13854 Epn1 MGI:MGI:1333763|Ensembl:ENSMUSG00000035203|Vega:OTTMUSG00000026130 +13855 Epn2 MGI:MGI:1333766|Ensembl:ENSMUSG00000001036|Vega:OTTMUSG00000005838 +13856 Epo MGI:MGI:95407|Ensembl:ENSMUSG00000029711|Vega:OTTMUSG00000021944 +13857 Epor MGI:MGI:95408|Ensembl:ENSMUSG00000006235|Vega:OTTMUSG00000062323 +13858 Eps15 MGI:MGI:104583|Ensembl:ENSMUSG00000028552|Vega:OTTMUSG00000008289 +13859 Eps15l1 MGI:MGI:104582|Ensembl:ENSMUSG00000006276|Vega:OTTMUSG00000062100 +13860 Eps8 MGI:MGI:104684|Ensembl:ENSMUSG00000015766|Vega:OTTMUSG00000022767 +13861 Epx MGI:MGI:107569|Ensembl:ENSMUSG00000052234|Vega:OTTMUSG00000001435 +13863 Lcn5 MGI:MGI:1277241|Ensembl:ENSMUSG00000026937|Vega:OTTMUSG00000012512 +13864 Nr2f6 MGI:MGI:1352453|Ensembl:ENSMUSG00000002393|Vega:OTTMUSG00000022854 +13865 Nr2f1 MGI:MGI:1352451|Ensembl:ENSMUSG00000069171|Vega:OTTMUSG00000023087 +13866 Erbb2 MGI:MGI:95410|Ensembl:ENSMUSG00000062312|Vega:OTTMUSG00000002711 +13867 Erbb3 MGI:MGI:95411|Ensembl:ENSMUSG00000018166|Vega:OTTMUSG00000029881 +13869 Erbb4 MGI:MGI:104771|Ensembl:ENSMUSG00000062209|Vega:OTTMUSG00000025138 +13870 Ercc1 MGI:MGI:95412|Ensembl:ENSMUSG00000003549|Vega:OTTMUSG00000030622 +13871 Ercc2 MGI:MGI:95413|Ensembl:ENSMUSG00000030400|Vega:OTTMUSG00000023168 +13872 Ercc3 MGI:MGI:95414|Ensembl:ENSMUSG00000024382|Vega:OTTMUSG00000023961 +13874 Ereg MGI:MGI:107508|Ensembl:ENSMUSG00000029377|Vega:OTTMUSG00000055519 +13875 Erf MGI:MGI:109637|Ensembl:ENSMUSG00000040857|Vega:OTTMUSG00000029200 +13876 Erg MGI:MGI:95415|Ensembl:ENSMUSG00000040732|Vega:OTTMUSG00000026424 +13877 Erh MGI:MGI:108089|Ensembl:ENSMUSG00000021131|Vega:OTTMUSG00000035813 +13884 Ces1c MGI:MGI:95420|Ensembl:ENSMUSG00000057400|Vega:OTTMUSG00000024453 +13885 Esd MGI:MGI:95421|Ensembl:ENSMUSG00000021996|Vega:OTTMUSG00000042019 +13897 Ces1e MGI:MGI:95432|Ensembl:ENSMUSG00000061959|Vega:OTTMUSG00000024535 +13909 Ces3b MGI:MGI:3644960|Ensembl:ENSMUSG00000062181|Vega:OTTMUSG00000037587 +13924 Ptprv MGI:MGI:108027 +13927 X83325 MGI:MGI:104839 +13929 Amz2 MGI:MGI:104837|Ensembl:ENSMUSG00000020610|Vega:OTTMUSG00000003345 +13933 X83338 MGI:MGI:104833 +13935 X83348 MGI:MGI:104831 +13938 X83360 MGI:MGI:104828 +13957 X83313 MGI:MGI:104826 +13972 Gnb1l MGI:MGI:1338057|Ensembl:ENSMUSG00000000884|Vega:OTTMUSG00000021511 +13980 X83319 MGI:MGI:104822 +13982 Esr1 MGI:MGI:1352467|Ensembl:ENSMUSG00000019768|Vega:OTTMUSG00000020886 +13983 Esr2 MGI:MGI:109392|Ensembl:ENSMUSG00000021055|Vega:OTTMUSG00000021138 +13984 Esx1 MGI:MGI:1096388|Ensembl:ENSMUSG00000023443|Vega:OTTMUSG00000018836 +13990 Smarcad1 MGI:MGI:95453|Ensembl:ENSMUSG00000029920|Vega:OTTMUSG00000057081 +13992 Khdrbs3 MGI:MGI:1313312|Ensembl:ENSMUSG00000022332 +13995 Etohd1 MGI:MGI:1261416 +13996 Etohd2 MGI:MGI:1261417|Ensembl:ENSMUSG00000089875 +13997 Etohd3 MGI:MGI:1261418 +13998 Fgd6 MGI:MGI:1261419|Ensembl:ENSMUSG00000020021|Vega:OTTMUSG00000030985 +13999 Gm14288 MGI:MGI:3706570|Ensembl:ENSMUSG00000078889|Vega:OTTMUSG00000016199 +14000 Drosha MGI:MGI:1261425|Ensembl:ENSMUSG00000022191|Vega:OTTMUSG00000023663 +14001 Etohi3 MGI:MGI:1261432 +14003 Etohi5 MGI:MGI:1261429 +14004 Chchd2 MGI:MGI:1261428|Ensembl:ENSMUSG00000070493|Vega:OTTMUSG00000024020 +14005 Etohi7 MGI:MGI:1261427 +14006 Etohi8 MGI:MGI:1261424 +14007 Celf2 MGI:MGI:1338822|Ensembl:ENSMUSG00000002107|Vega:OTTMUSG00000011788 +14008 Etv2 MGI:MGI:99253|Ensembl:ENSMUSG00000006311|Vega:OTTMUSG00000023405 +14009 Etv1 MGI:MGI:99254|Ensembl:ENSMUSG00000004151|Vega:OTTMUSG00000035098 +14011 Etv6 MGI:MGI:109336|Ensembl:ENSMUSG00000030199|Vega:OTTMUSG00000025993 +14012 Mpzl2 MGI:MGI:1289160|Ensembl:ENSMUSG00000032092|Vega:OTTMUSG00000016711 +14013 Mecom MGI:MGI:95457|Ensembl:ENSMUSG00000027684|Vega:OTTMUSG00000038143 +14016 Evi12 MGI:MGI:1336179 +14017 Evi2a MGI:MGI:95458|Ensembl:ENSMUSG00000078771|Vega:OTTMUSG00000000196 +14020 Evi5 MGI:MGI:104736|Ensembl:ENSMUSG00000011831|Vega:OTTMUSG00000028964 +14025 Bcl11a MGI:MGI:106190|Ensembl:ENSMUSG00000000861|Vega:OTTMUSG00000005291 +14026 Evl MGI:MGI:1194884|Ensembl:ENSMUSG00000021262 +14027 Evpl MGI:MGI:107507|Ensembl:ENSMUSG00000034282|Vega:OTTMUSG00000003838 +14028 Evx1 MGI:MGI:95461|Ensembl:ENSMUSG00000005503|Vega:OTTMUSG00000018871 +14029 Evx2 MGI:MGI:95462|Ensembl:ENSMUSG00000001815|Vega:OTTMUSG00000013302 +14030 Ewsr1 MGI:MGI:99960|Ensembl:ENSMUSG00000009079|Vega:OTTMUSG00000005079 +14033 exed MGI:MGI:95465 +14034 exf MGI:MGI:95466 +14036 exma MGI:MGI:1313145 +14038 Wfdc18 MGI:MGI:107506|Ensembl:ENSMUSG00000000983|Vega:OTTMUSG00000000970 +14042 Ext1 MGI:MGI:894663|Ensembl:ENSMUSG00000061731|Vega:OTTMUSG00000019491 +14043 Ext2 MGI:MGI:108050|Ensembl:ENSMUSG00000027198|Vega:OTTMUSG00000014564 +14047 ey2 MGI:MGI:95471 +14048 Eya1 MGI:MGI:109344|Ensembl:ENSMUSG00000025932|Vega:OTTMUSG00000049176 +14049 Eya2 MGI:MGI:109341|Ensembl:ENSMUSG00000017897|Vega:OTTMUSG00000001181 +14050 Eya3 MGI:MGI:109339|Ensembl:ENSMUSG00000028886|Vega:OTTMUSG00000009803 +14051 Eya4 MGI:MGI:1337104|Ensembl:ENSMUSG00000010461 +14055 Ezh1 MGI:MGI:1097695|Ensembl:ENSMUSG00000006920|Vega:OTTMUSG00000002729 +14056 Ezh2 MGI:MGI:107940|Ensembl:ENSMUSG00000029687|Vega:OTTMUSG00000021193 +14057 Sfxn1 MGI:MGI:2137677|Ensembl:ENSMUSG00000021474 +14058 F10 MGI:MGI:103107|Ensembl:ENSMUSG00000031444|Vega:OTTMUSG00000020614 +14060 F13b MGI:MGI:88379|Ensembl:ENSMUSG00000026368|Vega:OTTMUSG00000021467 +14061 F2 MGI:MGI:88380|Ensembl:ENSMUSG00000027249|Vega:OTTMUSG00000014282 +14062 F2r MGI:MGI:101802|Ensembl:ENSMUSG00000048376 +14063 F2rl1 MGI:MGI:101910|Ensembl:ENSMUSG00000021678 +14064 F2rl2 MGI:MGI:1298208|Ensembl:ENSMUSG00000021675|Vega:OTTMUSG00000036603 +14065 F2rl3 MGI:MGI:1298207|Ensembl:ENSMUSG00000050147|Vega:OTTMUSG00000062066 +14066 F3 MGI:MGI:88381|Ensembl:ENSMUSG00000028128|Vega:OTTMUSG00000052233 +14067 F5 MGI:MGI:88382|Ensembl:ENSMUSG00000026579|Vega:OTTMUSG00000034808 +14068 F7 MGI:MGI:109325|Ensembl:ENSMUSG00000031443|Vega:OTTMUSG00000020609 +14069 F8 MGI:MGI:88383|Ensembl:ENSMUSG00000031196|Vega:OTTMUSG00000020850 +14070 F8a MGI:MGI:95474|Ensembl:ENSMUSG00000078317|Vega:OTTMUSG00000017669 +14071 F9 MGI:MGI:88384|Ensembl:ENSMUSG00000031138|Vega:OTTMUSG00000018393 +14072 fa MGI:MGI:95475 +14073 Faah MGI:MGI:109609|Ensembl:ENSMUSG00000034171|Vega:OTTMUSG00000008726 +14074 Fabp3-ps1 MGI:MGI:101929 +14077 Fabp3 MGI:MGI:95476|Ensembl:ENSMUSG00000028773|Vega:OTTMUSG00000009558 +14079 Fabp2 MGI:MGI:95478|Ensembl:ENSMUSG00000023057|Vega:OTTMUSG00000035257 +14080 Fabp1 MGI:MGI:95479|Ensembl:ENSMUSG00000054422|Vega:OTTMUSG00000023123 +14081 Acsl1 MGI:MGI:102797|Ensembl:ENSMUSG00000018796|Vega:OTTMUSG00000022668 +14082 Fadd MGI:MGI:109324|Ensembl:ENSMUSG00000031077|Vega:OTTMUSG00000033373 +14083 Ptk2 MGI:MGI:95481|Ensembl:ENSMUSG00000022607 +14084 Faf1 MGI:MGI:109419|Ensembl:ENSMUSG00000010517|Vega:OTTMUSG00000008482 +14085 Fah MGI:MGI:95482|Ensembl:ENSMUSG00000030630|Vega:OTTMUSG00000025072 +14086 Fscn1 MGI:MGI:1352745|Ensembl:ENSMUSG00000029581|Vega:OTTMUSG00000026105 +14087 Fanca MGI:MGI:1341823|Ensembl:ENSMUSG00000032815|Vega:OTTMUSG00000030114 +14088 Fancc MGI:MGI:95480|Ensembl:ENSMUSG00000021461|Vega:OTTMUSG00000030853 +14089 Fap MGI:MGI:109608|Ensembl:ENSMUSG00000000392|Vega:OTTMUSG00000012825 +14102 Fas MGI:MGI:95484|Ensembl:ENSMUSG00000024778 +14103 Fasl MGI:MGI:99255|Ensembl:ENSMUSG00000000817|Vega:OTTMUSG00000050992 +14104 Fasn MGI:MGI:95485|Ensembl:ENSMUSG00000025153|Vega:OTTMUSG00000004143 +14105 Srsf10 MGI:MGI:1333805|Ensembl:ENSMUSG00000028676|Vega:OTTMUSG00000009794 +14106 Foxh1 MGI:MGI:1347465|Ensembl:ENSMUSG00000033837 +14107 Fat1 MGI:MGI:109168|Ensembl:ENSMUSG00000070047|Vega:OTTMUSG00000048086 +14109 Fau MGI:MGI:102547|Ensembl:ENSMUSG00000038274 +14110 Fau-ps1 MGI:MGI:103030 +14111 Fau-ps2 MGI:MGI:103018 +14112 Fau-ps3 MGI:MGI:1095402 +14113 Fbl MGI:MGI:95486|Ensembl:ENSMUSG00000046865|Vega:OTTMUSG00000058942 +14114 Fbln1 MGI:MGI:95487|Ensembl:ENSMUSG00000006369|Vega:OTTMUSG00000030663 +14115 Fbln2 MGI:MGI:95488|Ensembl:ENSMUSG00000064080|Vega:OTTMUSG00000022459 +14118 Fbn1 MGI:MGI:95489|Ensembl:ENSMUSG00000027204|Vega:OTTMUSG00000015332 +14119 Fbn2 MGI:MGI:95490|Ensembl:ENSMUSG00000024598 +14120 Fbp2 MGI:MGI:95491|Ensembl:ENSMUSG00000021456 +14121 Fbp1 MGI:MGI:95492|Ensembl:ENSMUSG00000069805|Vega:OTTMUSG00000026406 +14123 Fbrs MGI:MGI:104648|Ensembl:ENSMUSG00000042423|Vega:OTTMUSG00000058623 +14124 fc MGI:MGI:95493 +14125 Fcer1a MGI:MGI:95494|Ensembl:ENSMUSG00000005339|Vega:OTTMUSG00000050168 +14126 Ms4a2 MGI:MGI:95495|Ensembl:ENSMUSG00000024680|Vega:OTTMUSG00000047239 +14127 Fcer1g MGI:MGI:95496|Ensembl:ENSMUSG00000058715|Vega:OTTMUSG00000021504 +14128 Fcer2a MGI:MGI:95497|Ensembl:ENSMUSG00000005540|Vega:OTTMUSG00000059173 +14129 Fcgr1 MGI:MGI:95498|Ensembl:ENSMUSG00000015947|Vega:OTTMUSG00000053089 +14130 Fcgr2b MGI:MGI:95499|Ensembl:ENSMUSG00000026656|Vega:OTTMUSG00000021775 +14131 Fcgr3 MGI:MGI:95500|Ensembl:ENSMUSG00000059498|Vega:OTTMUSG00000035155 +14132 Fcgrt MGI:MGI:103017|Ensembl:ENSMUSG00000003420|Vega:OTTMUSG00000058708 +14133 Fcna MGI:MGI:1340905|Ensembl:ENSMUSG00000026938|Vega:OTTMUSG00000012513 +14134 Fcnb MGI:MGI:1341158|Ensembl:ENSMUSG00000026835|Vega:OTTMUSG00000011624 +14136 fd MGI:MGI:95502 +14137 Fdft1 MGI:MGI:102706|Ensembl:ENSMUSG00000021273 +14148 Fdx1 MGI:MGI:103224|Ensembl:ENSMUSG00000032051|Vega:OTTMUSG00000063088 +14149 Fdxr MGI:MGI:104724|Ensembl:ENSMUSG00000018861|Vega:OTTMUSG00000003745 +14150 fe MGI:MGI:95512 +14151 Fech MGI:MGI:95513|Ensembl:ENSMUSG00000024588 +14154 Fem1a MGI:MGI:1335089|Ensembl:ENSMUSG00000043683 +14155 Fem1b MGI:MGI:1335087|Ensembl:ENSMUSG00000032244|Vega:OTTMUSG00000062562 +14156 Fen1 MGI:MGI:102779|Ensembl:ENSMUSG00000024742|Vega:OTTMUSG00000034053 +14158 Fer MGI:MGI:105917|Ensembl:ENSMUSG00000000127 +14159 Fes MGI:MGI:95514|Ensembl:ENSMUSG00000053158|Vega:OTTMUSG00000058666 +14160 Lgr5 MGI:MGI:1341817|Ensembl:ENSMUSG00000020140|Vega:OTTMUSG00000020836 +14161 Fga MGI:MGI:1316726|Ensembl:ENSMUSG00000028001|Vega:OTTMUSG00000051803 +14163 Fgd1 MGI:MGI:104566|Ensembl:ENSMUSG00000025265|Vega:OTTMUSG00000019292 +14164 Fgf1 MGI:MGI:95515|Ensembl:ENSMUSG00000036585|Vega:OTTMUSG00000020317 +14165 Fgf10 MGI:MGI:1099809|Ensembl:ENSMUSG00000021732|Vega:OTTMUSG00000032890 +14166 Fgf11 MGI:MGI:109167|Ensembl:ENSMUSG00000042826|Vega:OTTMUSG00000006004 +14167 Fgf12 MGI:MGI:109183|Ensembl:ENSMUSG00000022523 +14168 Fgf13 MGI:MGI:109178|Ensembl:ENSMUSG00000031137|Vega:OTTMUSG00000018392 +14169 Fgf14 MGI:MGI:109189|Ensembl:ENSMUSG00000025551|Vega:OTTMUSG00000021491 +14170 Fgf15 MGI:MGI:1096383|Ensembl:ENSMUSG00000031073|Vega:OTTMUSG00000059889 +14171 Fgf17 MGI:MGI:1202401|Ensembl:ENSMUSG00000022101 +14172 Fgf18 MGI:MGI:1277980|Ensembl:ENSMUSG00000057967|Vega:OTTMUSG00000005390 +14173 Fgf2 MGI:MGI:95516|Ensembl:ENSMUSG00000037225|Vega:OTTMUSG00000007393 +14174 Fgf3 MGI:MGI:95517|Ensembl:ENSMUSG00000031074|Vega:OTTMUSG00000031027 +14175 Fgf4 MGI:MGI:95518|Ensembl:ENSMUSG00000050917|Vega:OTTMUSG00000059887 +14176 Fgf5 MGI:MGI:95519|Ensembl:ENSMUSG00000029337|Vega:OTTMUSG00000053547 +14177 Fgf6 MGI:MGI:95520|Ensembl:ENSMUSG00000000183|Vega:OTTMUSG00000056342 +14178 Fgf7 MGI:MGI:95521|Ensembl:ENSMUSG00000027208|Vega:OTTMUSG00000015341 +14179 Fgf8 MGI:MGI:99604|Ensembl:ENSMUSG00000025219|Vega:OTTMUSG00000021697 +14180 Fgf9 MGI:MGI:104723|Ensembl:ENSMUSG00000021974|Vega:OTTMUSG00000036883 +14181 Fgfbp1 MGI:MGI:1096350|Ensembl:ENSMUSG00000048373|Vega:OTTMUSG00000029016 +14182 Fgfr1 MGI:MGI:95522|Ensembl:ENSMUSG00000031565|Vega:OTTMUSG00000031031 +14183 Fgfr2 MGI:MGI:95523|Ensembl:ENSMUSG00000030849|Vega:OTTMUSG00000031222 +14184 Fgfr3 MGI:MGI:95524|Ensembl:ENSMUSG00000054252|Vega:OTTMUSG00000021524 +14185 Fgfr3-ps MGI:MGI:109607 +14186 Fgfr4 MGI:MGI:95525|Ensembl:ENSMUSG00000005320|Vega:OTTMUSG00000035043 +14187 Akr1b8 MGI:MGI:107673|Ensembl:ENSMUSG00000029762|Vega:OTTMUSG00000014787 +14190 Fgl2 MGI:MGI:103266|Ensembl:ENSMUSG00000039899|Vega:OTTMUSG00000025650 +14191 Fgr MGI:MGI:95527|Ensembl:ENSMUSG00000028874|Vega:OTTMUSG00000010096 +14193 fh MGI:MGI:95529 +14194 Fh1 MGI:MGI:95530|Ensembl:ENSMUSG00000026526|Vega:OTTMUSG00000025588 +14195 fhd MGI:MGI:95531 +14198 Fhit MGI:MGI:1277947|Ensembl:ENSMUSG00000060579|Vega:OTTMUSG00000034621 +14199 Fhl1 MGI:MGI:1298387|Ensembl:ENSMUSG00000023092|Vega:OTTMUSG00000017580 +14200 Fhl2 MGI:MGI:1338762|Ensembl:ENSMUSG00000008136|Vega:OTTMUSG00000046311 +14201 Fhl3 MGI:MGI:1341092|Ensembl:ENSMUSG00000032643|Vega:OTTMUSG00000009181 +14202 Fhl4 MGI:MGI:1338765|Ensembl:ENSMUSG00000050035|Vega:OTTMUSG00000063529 +14204 Il4i1 MGI:MGI:109552|Ensembl:ENSMUSG00000074141|Vega:OTTMUSG00000029474 +14205 Vegfd MGI:MGI:108037|Ensembl:ENSMUSG00000031380|Vega:OTTMUSG00000019516 +14208 Ppm1g MGI:MGI:106065|Ensembl:ENSMUSG00000029147|Vega:OTTMUSG00000055347 +14211 Smc2 MGI:MGI:106067|Ensembl:ENSMUSG00000028312|Vega:OTTMUSG00000007033 +14218 Sh3pxd2a MGI:MGI:1298393|Ensembl:ENSMUSG00000053617 +14219 Ctgf MGI:MGI:95537|Ensembl:ENSMUSG00000019997|Vega:OTTMUSG00000019709 +14221 Fjx1 MGI:MGI:1341907|Ensembl:ENSMUSG00000075012|Vega:OTTMUSG00000014838 +14223 Fkbp1a-ps2 MGI:MGI:107772 +14225 Fkbp1a MGI:MGI:95541|Ensembl:ENSMUSG00000032966|Vega:OTTMUSG00000015867 +14226 Fkbp1b MGI:MGI:1336205|Ensembl:ENSMUSG00000020635 +14227 Fkbp2 MGI:MGI:95542|Ensembl:ENSMUSG00000056629 +14228 Fkbp4 MGI:MGI:95543|Ensembl:ENSMUSG00000030357|Vega:OTTMUSG00000024637 +14229 Fkbp5 MGI:MGI:104670|Ensembl:ENSMUSG00000024222|Vega:OTTMUSG00000024255 +14230 Fkbp10 MGI:MGI:104769|Ensembl:ENSMUSG00000001555|Vega:OTTMUSG00000006274 +14231 Fkbp7 MGI:MGI:1336879|Ensembl:ENSMUSG00000002732|Vega:OTTMUSG00000013130 +14232 Fkbp8 MGI:MGI:1341070|Ensembl:ENSMUSG00000019428|Vega:OTTMUSG00000031159 +14233 Foxi1 MGI:MGI:1096329|Ensembl:ENSMUSG00000047861|Vega:OTTMUSG00000005407 +14234 Foxc2 MGI:MGI:1347481|Ensembl:ENSMUSG00000046714|Vega:OTTMUSG00000043022 +14235 Foxm1 MGI:MGI:1347487|Ensembl:ENSMUSG00000001517|Vega:OTTMUSG00000023770 +14236 Foxn2 MGI:MGI:1347478|Ensembl:ENSMUSG00000034998|Vega:OTTMUSG00000033848 +14237 Foxd4 MGI:MGI:1347467|Ensembl:ENSMUSG00000051490 +14238 Foxf2 MGI:MGI:1347479|Ensembl:ENSMUSG00000038402|Vega:OTTMUSG00000000735 +14239 Foxs1 MGI:MGI:95546|Ensembl:ENSMUSG00000074676|Vega:OTTMUSG00000015823 +14240 Foxb2 MGI:MGI:1347468|Ensembl:ENSMUSG00000056829 +14241 Foxl1 MGI:MGI:1347469|Ensembl:ENSMUSG00000097084|Vega:OTTMUSG00000043023 +14245 Lpin1 MGI:MGI:1891340|Ensembl:ENSMUSG00000020593 +14246 Flg MGI:MGI:95553 +14247 Fli1 MGI:MGI:95554|Ensembl:ENSMUSG00000016087|Vega:OTTMUSG00000044678 +14248 Flii MGI:MGI:1342286|Ensembl:ENSMUSG00000002812|Vega:OTTMUSG00000007748 +14251 Flot1 MGI:MGI:1100500|Ensembl:ENSMUSG00000059714|Vega:OTTMUSG00000037406 +14252 Flot2 MGI:MGI:103309|Ensembl:ENSMUSG00000061981|Vega:OTTMUSG00000000070 +14254 Flt1 MGI:MGI:95558|Ensembl:ENSMUSG00000029648|Vega:OTTMUSG00000021385 +14255 Flt3 MGI:MGI:95559|Ensembl:ENSMUSG00000042817|Vega:OTTMUSG00000020408 +14256 Flt3l MGI:MGI:95560|Ensembl:ENSMUSG00000110206|Vega:OTTMUSG00000033411 +14257 Flt4 MGI:MGI:95561|Ensembl:ENSMUSG00000020357|Vega:OTTMUSG00000005554 +14259 fm MGI:MGI:95563 +14260 Fmn1 MGI:MGI:101815|Ensembl:ENSMUSG00000044042|Vega:OTTMUSG00000015195 +14261 Fmo1 MGI:MGI:1310002|Ensembl:ENSMUSG00000040181|Vega:OTTMUSG00000024069 +14262 Fmo3 MGI:MGI:1100496|Ensembl:ENSMUSG00000026691|Vega:OTTMUSG00000024141 +14263 Fmo5 MGI:MGI:1310004|Ensembl:ENSMUSG00000028088|Vega:OTTMUSG00000023708 +14264 Fmod MGI:MGI:1328364|Ensembl:ENSMUSG00000041559|Vega:OTTMUSG00000034789 +14265 Fmr1 MGI:MGI:95564|Ensembl:ENSMUSG00000000838|Vega:OTTMUSG00000017748 +14266 Aff2 MGI:MGI:1202294|Ensembl:ENSMUSG00000031189|Vega:OTTMUSG00000017765 +14268 Fn1 MGI:MGI:95566|Ensembl:ENSMUSG00000026193|Vega:OTTMUSG00000048807 +14269 Fnbp1 MGI:MGI:109606|Ensembl:ENSMUSG00000075415|Vega:OTTMUSG00000011868 +14270 Srgap2 MGI:MGI:109605|Ensembl:ENSMUSG00000026425|Vega:OTTMUSG00000049188 +14271 Fnld MGI:MGI:1309996 +14272 Fnta MGI:MGI:104683|Ensembl:ENSMUSG00000015994|Vega:OTTMUSG00000060878 +14275 Folr1 MGI:MGI:95568|Ensembl:ENSMUSG00000001827|Vega:OTTMUSG00000022222 +14276 Folr2 MGI:MGI:95569|Ensembl:ENSMUSG00000032725|Vega:OTTMUSG00000060437 +14281 Fos MGI:MGI:95574|Ensembl:ENSMUSG00000021250|Vega:OTTMUSG00000019764 +14282 Fosb MGI:MGI:95575|Ensembl:ENSMUSG00000003545|Vega:OTTMUSG00000059145 +14283 Fosl1 MGI:MGI:107179|Ensembl:ENSMUSG00000024912 +14284 Fosl2 MGI:MGI:102858|Ensembl:ENSMUSG00000029135|Vega:OTTMUSG00000055218 +14287 Fpgs MGI:MGI:95576|Ensembl:ENSMUSG00000009566|Vega:OTTMUSG00000012531 +14289 Fpr2 MGI:MGI:1278319|Ensembl:ENSMUSG00000052270|Vega:OTTMUSG00000021056 +14290 Fpr-rs3 MGI:MGI:1278318|Ensembl:ENSMUSG00000060701|Vega:OTTMUSG00000039785 +14291 Fpr-rs4 MGI:MGI:1278317|Ensembl:ENSMUSG00000048062|Vega:OTTMUSG00000039013 +14293 Fpr1 MGI:MGI:107443|Ensembl:ENSMUSG00000045551|Vega:OTTMUSG00000021779 +14294 Fpr3 MGI:MGI:1194495|Ensembl:ENSMUSG00000079700|Vega:OTTMUSG00000021780 +14296 Frat1 MGI:MGI:109450|Ensembl:ENSMUSG00000067199|Vega:OTTMUSG00000060253 +14297 Fxn MGI:MGI:1096879|Ensembl:ENSMUSG00000059363|Vega:OTTMUSG00000031872 +14299 Ncs1 MGI:MGI:109166|Ensembl:ENSMUSG00000062661|Vega:OTTMUSG00000011923 +14300 Frg1 MGI:MGI:893597|Ensembl:ENSMUSG00000031590|Vega:OTTMUSG00000061156 +14302 Frk MGI:MGI:103265|Ensembl:ENSMUSG00000019779|Vega:OTTMUSG00000063874 +14308 Fshb MGI:MGI:95582|Ensembl:ENSMUSG00000027120|Vega:OTTMUSG00000015038 +14309 Fshr MGI:MGI:95583|Ensembl:ENSMUSG00000032937 +14311 Cidec MGI:MGI:95585|Ensembl:ENSMUSG00000030278|Vega:OTTMUSG00000023130 +14312 Brd2 MGI:MGI:99495|Ensembl:ENSMUSG00000024335|Vega:OTTMUSG00000017279 +14313 Fst MGI:MGI:95586|Ensembl:ENSMUSG00000021765 +14314 Fstl1 MGI:MGI:102793|Ensembl:ENSMUSG00000022816|Vega:OTTMUSG00000025717 +14317 Ftcd MGI:MGI:1339962|Ensembl:ENSMUSG00000001155|Vega:OTTMUSG00000020446 +14319 Fth1 MGI:MGI:95588|Ensembl:ENSMUSG00000024661 +14320 Fth-ps1 MGI:MGI:104595 +14321 Fth-ps2 MGI:MGI:104594 +14322 Fth-ps3 MGI:MGI:104623 +14325 Ftl1 MGI:MGI:95589|Ensembl:ENSMUSG00000050708|Vega:OTTMUSG00000022565 +14337 Ftl2-ps MGI:MGI:95590 +14339 Aktip MGI:MGI:3693832|Ensembl:ENSMUSG00000031667|Vega:OTTMUSG00000031747 +14343 Fut1 MGI:MGI:109375|Ensembl:ENSMUSG00000008461|Vega:OTTMUSG00000058295 +14344 Fut2 MGI:MGI:109374|Ensembl:ENSMUSG00000055978|Vega:OTTMUSG00000058296 +14345 Fut4 MGI:MGI:95594|Ensembl:ENSMUSG00000049307|Vega:OTTMUSG00000062776 +14346 Fut4-ps1 MGI:MGI:104647 +14347 Fut7 MGI:MGI:107692|Ensembl:ENSMUSG00000036587|Vega:OTTMUSG00000012106 +14348 Fut9 MGI:MGI:1330859|Ensembl:ENSMUSG00000055373|Vega:OTTMUSG00000004810 +14349 Fv1 MGI:MGI:95595|Ensembl:ENSMUSG00000070583|Vega:OTTMUSG00000040078 +14352 Fv4 MGI:MGI:95598 +14356 Timm10b MGI:MGI:1315196|Ensembl:ENSMUSG00000089847|Ensembl:ENSMUSG00000110234|Vega:OTTMUSG00000025567|Vega:OTTMUSG00000060426 +14357 Dtx1 MGI:MGI:1352744|Ensembl:ENSMUSG00000029603|Vega:OTTMUSG00000025278 +14359 Fxr1 MGI:MGI:104860|Ensembl:ENSMUSG00000027680|Vega:OTTMUSG00000052173 +14360 Fyn MGI:MGI:95602|Ensembl:ENSMUSG00000019843|Vega:OTTMUSG00000034130 +14362 Fzd1 MGI:MGI:1196625|Ensembl:ENSMUSG00000044674|Vega:OTTMUSG00000021313 +14365 Fzd3 MGI:MGI:108476|Ensembl:ENSMUSG00000007989|Vega:OTTMUSG00000020983 +14366 Fzd4 MGI:MGI:108520|Ensembl:ENSMUSG00000049791|Vega:OTTMUSG00000059643 +14367 Fzd5 MGI:MGI:108571|Ensembl:ENSMUSG00000045005|Vega:OTTMUSG00000047622 +14368 Fzd6 MGI:MGI:108474|Ensembl:ENSMUSG00000022297 +14369 Fzd7 MGI:MGI:108570|Ensembl:ENSMUSG00000041075|Vega:OTTMUSG00000020777 +14370 Fzd8 MGI:MGI:108460|Ensembl:ENSMUSG00000036904 +14371 Fzd9 MGI:MGI:1313278|Ensembl:ENSMUSG00000049551|Vega:OTTMUSG00000021311 +14373 G0s2 MGI:MGI:1316737|Ensembl:ENSMUSG00000009633|Vega:OTTMUSG00000050857 +14375 Xrcc6 MGI:MGI:95606|Ensembl:ENSMUSG00000022471|Vega:OTTMUSG00000035734 +14376 Ganab MGI:MGI:1097667|Ensembl:ENSMUSG00000071650 +14377 G6pc MGI:MGI:95607|Ensembl:ENSMUSG00000078650|Vega:OTTMUSG00000002811 +14378 G6pc2 MGI:MGI:1277193|Ensembl:ENSMUSG00000005232|Vega:OTTMUSG00000012981 +14380 G6pd2 MGI:MGI:105977|Ensembl:ENSMUSG00000089992|Vega:OTTMUSG00000025208 +14381 G6pdx MGI:MGI:105979|Ensembl:ENSMUSG00000031400|Vega:OTTMUSG00000017699 +14385 Slc37a4 MGI:MGI:1316650|Ensembl:ENSMUSG00000032114|Vega:OTTMUSG00000063272 +14387 Gaa MGI:MGI:95609|Ensembl:ENSMUSG00000025579|Vega:OTTMUSG00000003997 +14388 Gab1 MGI:MGI:108088|Ensembl:ENSMUSG00000031714|Vega:OTTMUSG00000061338 +14389 Gab2 MGI:MGI:1333854|Ensembl:ENSMUSG00000004508|Vega:OTTMUSG00000058176 +14390 Gabpa MGI:MGI:95610|Ensembl:ENSMUSG00000008976|Vega:OTTMUSG00000025176 +14391 Gabpb1 MGI:MGI:95611|Ensembl:ENSMUSG00000027361|Vega:OTTMUSG00000015863 +14394 Gabra1 MGI:MGI:95613|Ensembl:ENSMUSG00000010803|Vega:OTTMUSG00000005445 +14395 Gabra2 MGI:MGI:95614|Ensembl:ENSMUSG00000000560|Vega:OTTMUSG00000054189 +14396 Gabra3 MGI:MGI:95615|Ensembl:ENSMUSG00000031343|Vega:OTTMUSG00000017849 +14397 Gabra4 MGI:MGI:95616|Ensembl:ENSMUSG00000029211|Vega:OTTMUSG00000054261 +14399 Gabra6 MGI:MGI:95618|Ensembl:ENSMUSG00000020428|Vega:OTTMUSG00000006343 +14400 Gabrb1 MGI:MGI:95619|Ensembl:ENSMUSG00000029212|Vega:OTTMUSG00000024372 +14401 Gabrb2 MGI:MGI:95620|Ensembl:ENSMUSG00000007653|Vega:OTTMUSG00000006331 +14402 Gabrb3 MGI:MGI:95621|Ensembl:ENSMUSG00000033676|Vega:OTTMUSG00000031173 +14403 Gabrd MGI:MGI:95622|Ensembl:ENSMUSG00000029054|Vega:OTTMUSG00000010612 +14404 Gabre MGI:MGI:1330235|Ensembl:ENSMUSG00000031340|Vega:OTTMUSG00000017844 +14405 Gabrg1 MGI:MGI:103156|Ensembl:ENSMUSG00000001260|Vega:OTTMUSG00000054188 +14406 Gabrg2 MGI:MGI:95623|Ensembl:ENSMUSG00000020436|Vega:OTTMUSG00000006345 +14407 Gabrg3 MGI:MGI:95624|Ensembl:ENSMUSG00000055026|Vega:OTTMUSG00000024708 +14408 Gabrr1 MGI:MGI:95625|Ensembl:ENSMUSG00000028280|Vega:OTTMUSG00000004921 +14409 Gabrr2 MGI:MGI:95626|Ensembl:ENSMUSG00000023267|Vega:OTTMUSG00000004918 +14411 Slc6a12 MGI:MGI:95628|Ensembl:ENSMUSG00000030109|Vega:OTTMUSG00000036447 +14412 Slc6a13 MGI:MGI:95629|Ensembl:ENSMUSG00000030108|Vega:OTTMUSG00000023510 +14415 Gad1 MGI:MGI:95632|Ensembl:ENSMUSG00000070880|Vega:OTTMUSG00000033269 +14417 Gad2 MGI:MGI:95634|Ensembl:ENSMUSG00000026787|Vega:OTTMUSG00000011505 +14419 Gal MGI:MGI:95637|Ensembl:ENSMUSG00000024907 +14420 Galc MGI:MGI:95636|Ensembl:ENSMUSG00000021003 +14421 B4galnt1 MGI:MGI:1342057|Ensembl:ENSMUSG00000006731 +14422 B4galnt2 MGI:MGI:1342058|Ensembl:ENSMUSG00000013418|Vega:OTTMUSG00000001755 +14423 Galnt1 MGI:MGI:894693|Ensembl:ENSMUSG00000000420|Vega:OTTMUSG00000036067 +14425 Galnt3 MGI:MGI:894695|Ensembl:ENSMUSG00000026994|Vega:OTTMUSG00000013003 +14426 Galnt4 MGI:MGI:894692|Ensembl:ENSMUSG00000090035|Vega:OTTMUSG00000032482 +14427 Galr1 MGI:MGI:1096364|Ensembl:ENSMUSG00000024553 +14428 Galr2 MGI:MGI:1337018|Ensembl:ENSMUSG00000020793|Vega:OTTMUSG00000003839 +14429 Galr3 MGI:MGI:1329003|Ensembl:ENSMUSG00000006378 +14430 Galt MGI:MGI:95638|Ensembl:ENSMUSG00000036073|Vega:OTTMUSG00000006678 +14431 Gamt MGI:MGI:1098221|Ensembl:ENSMUSG00000020150|Vega:OTTMUSG00000000008 +14432 Gap43 MGI:MGI:95639|Ensembl:ENSMUSG00000047261|Vega:OTTMUSG00000016275 +14433 Gapdh MGI:MGI:95640|Ensembl:ENSMUSG00000057666|Vega:OTTMUSG00000027118 +14447 Gapdhs MGI:MGI:95653|Ensembl:ENSMUSG00000061099|Vega:OTTMUSG00000043090 +14450 Gart MGI:MGI:95654|Ensembl:ENSMUSG00000022962|Vega:OTTMUSG00000028333 +14451 Gas1 MGI:MGI:95655|Ensembl:ENSMUSG00000052957|Vega:OTTMUSG00000033412 +14453 Gas2 MGI:MGI:95657|Ensembl:ENSMUSG00000030498|Vega:OTTMUSG00000024897 +14455 Gas5 MGI:MGI:95659|Ensembl:ENSMUSG00000053332 +14456 Gas6 MGI:MGI:95660|Ensembl:ENSMUSG00000031451|Vega:OTTMUSG00000060783 +14457 Gas7 MGI:MGI:1202388|Ensembl:ENSMUSG00000033066|Vega:OTTMUSG00000005930 +14459 Gast MGI:MGI:104768|Ensembl:ENSMUSG00000017165|Vega:OTTMUSG00000006278 +14460 Gata1 MGI:MGI:95661|Ensembl:ENSMUSG00000031162|Vega:OTTMUSG00000018011 +14461 Gata2 MGI:MGI:95662|Ensembl:ENSMUSG00000015053|Vega:OTTMUSG00000057342 +14462 Gata3 MGI:MGI:95663|Ensembl:ENSMUSG00000015619|Vega:OTTMUSG00000011129 +14463 Gata4 MGI:MGI:95664|Ensembl:ENSMUSG00000021944|Vega:OTTMUSG00000032593 +14464 Gata5 MGI:MGI:109497|Ensembl:ENSMUSG00000015627|Vega:OTTMUSG00000016299 +14465 Gata6 MGI:MGI:107516|Ensembl:ENSMUSG00000005836 +14466 Gba MGI:MGI:95665|Ensembl:ENSMUSG00000028048|Vega:OTTMUSG00000052631 +14467 Nipsnap2 MGI:MGI:1278343|Ensembl:ENSMUSG00000029432|Vega:OTTMUSG00000027638 +14468 Gbp2b MGI:MGI:95666|Ensembl:ENSMUSG00000040264|Vega:OTTMUSG00000035259 +14469 Gbp2 MGI:MGI:102772|Ensembl:ENSMUSG00000028270|Vega:OTTMUSG00000036785 +14470 Rabac1 MGI:MGI:1201692|Ensembl:ENSMUSG00000003380|Vega:OTTMUSG00000058240 +14472 Gbx2 MGI:MGI:95668|Ensembl:ENSMUSG00000034486|Vega:OTTMUSG00000037278 +14473 Gc MGI:MGI:95669|Ensembl:ENSMUSG00000035540|Vega:OTTMUSG00000055402 +14475 Gcap10 MGI:MGI:101861 +14479 Usp15 MGI:MGI:101857|Ensembl:ENSMUSG00000020124 +14489 Mtpn MGI:MGI:99445|Ensembl:ENSMUSG00000029840|Vega:OTTMUSG00000024162 +14525 Gcsam MGI:MGI:102969|Ensembl:ENSMUSG00000022659|Vega:OTTMUSG00000028492 +14526 Gcg MGI:MGI:95674|Ensembl:ENSMUSG00000000394|Vega:OTTMUSG00000012783 +14527 Gcgr MGI:MGI:99572|Ensembl:ENSMUSG00000025127|Vega:OTTMUSG00000004269 +14528 Gch1 MGI:MGI:95675|Ensembl:ENSMUSG00000037580 +14531 Gcm1 MGI:MGI:108045|Ensembl:ENSMUSG00000023333|Vega:OTTMUSG00000062910 +14533 Bloc1s1 MGI:MGI:1195276|Ensembl:ENSMUSG00000090247|Vega:OTTMUSG00000033474 +14534 Kat2a MGI:MGI:1343101|Ensembl:ENSMUSG00000020918|Vega:OTTMUSG00000002053 +14536 Nr6a1 MGI:MGI:1352459|Ensembl:ENSMUSG00000063972|Vega:OTTMUSG00000012347 +14537 Gcnt1 MGI:MGI:95676|Ensembl:ENSMUSG00000038843|Vega:OTTMUSG00000037187 +14538 Gcnt2 MGI:MGI:1100870|Ensembl:ENSMUSG00000021360 +14539 Opn1mw MGI:MGI:1097692|Ensembl:ENSMUSG00000031394|Vega:OTTMUSG00000017694 +14544 Gda MGI:MGI:95678|Ensembl:ENSMUSG00000058624|Vega:OTTMUSG00000028318 +14545 Gdap1 MGI:MGI:1338002|Ensembl:ENSMUSG00000025777|Vega:OTTMUSG00000022300 +14547 Gdap2 MGI:MGI:1338001|Ensembl:ENSMUSG00000027865|Vega:OTTMUSG00000006953 +14548 Mrps33 MGI:MGI:1338046|Ensembl:ENSMUSG00000029918|Vega:OTTMUSG00000024100 +14550 Gdap5 MGI:MGI:1337998 +14551 Gdap6 MGI:MGI:1337997 +14552 Gdap7 MGI:MGI:1337996 +14553 Gdap8 MGI:MGI:1338007 +14554 Gdap9 MGI:MGI:1338064 +14555 Gpd1 MGI:MGI:95679|Ensembl:ENSMUSG00000023019|Vega:OTTMUSG00000034997 +14559 Gdf1 MGI:MGI:95683|Ensembl:ENSMUSG00000087408|Ensembl:ENSMUSG00000109523|Vega:OTTMUSG00000042299 +14560 Gdf10 MGI:MGI:95684|Ensembl:ENSMUSG00000021943 +14561 Gdf11 MGI:MGI:1338027|Ensembl:ENSMUSG00000025352|Vega:OTTMUSG00000032829 +14562 Gdf3 MGI:MGI:95686|Ensembl:ENSMUSG00000030117|Vega:OTTMUSG00000021509 +14563 Gdf5 MGI:MGI:95688|Ensembl:ENSMUSG00000038259|Vega:OTTMUSG00000015989 +14566 Gdf9 MGI:MGI:95692|Ensembl:ENSMUSG00000018238|Vega:OTTMUSG00000000055 +14567 Gdi1 MGI:MGI:99846|Ensembl:ENSMUSG00000015291|Vega:OTTMUSG00000017683 +14569 Gdi2 MGI:MGI:99845|Ensembl:ENSMUSG00000021218 +14570 Arhgdig MGI:MGI:108430|Ensembl:ENSMUSG00000073433|Vega:OTTMUSG00000026505 +14571 Gpd2 MGI:MGI:99778|Ensembl:ENSMUSG00000026827|Vega:OTTMUSG00000012561 +14572 gdn MGI:MGI:95693 +14573 Gdnf MGI:MGI:107430|Ensembl:ENSMUSG00000022144 +14577 ge MGI:MGI:95696 +14579 Gem MGI:MGI:99844|Ensembl:ENSMUSG00000028214|Vega:OTTMUSG00000004518 +14580 Gfap MGI:MGI:95697|Ensembl:ENSMUSG00000020932|Vega:OTTMUSG00000003084 +14581 Gfi1 MGI:MGI:103170|Ensembl:ENSMUSG00000029275|Vega:OTTMUSG00000033123 +14582 Gfi1b MGI:MGI:1276578|Ensembl:ENSMUSG00000026815|Vega:OTTMUSG00000011746 +14583 Gfpt1 MGI:MGI:95698|Ensembl:ENSMUSG00000029992|Vega:OTTMUSG00000022939 +14584 Gfpt2 MGI:MGI:1338883|Ensembl:ENSMUSG00000020363|Vega:OTTMUSG00000005570 +14585 Gfra1 MGI:MGI:1100842|Ensembl:ENSMUSG00000025089|Vega:OTTMUSG00000033056 +14586 Gfra2 MGI:MGI:1195462|Ensembl:ENSMUSG00000022103 +14587 Gfra3 MGI:MGI:1201403|Ensembl:ENSMUSG00000024366 +14588 Gfra4 MGI:MGI:1341873|Ensembl:ENSMUSG00000027316|Vega:OTTMUSG00000015542 +14590 Ggh MGI:MGI:1329035|Ensembl:ENSMUSG00000073987|Vega:OTTMUSG00000006380 +14593 Ggps1 MGI:MGI:1341724|Ensembl:ENSMUSG00000021302 +14594 Ggta1 MGI:MGI:95704|Ensembl:ENSMUSG00000035778|Vega:OTTMUSG00000012125 +14595 B4galt1 MGI:MGI:95705|Ensembl:ENSMUSG00000028413|Vega:OTTMUSG00000006610 +14598 Ggt1 MGI:MGI:95706|Ensembl:ENSMUSG00000006345|Vega:OTTMUSG00000034127 +14599 Gh MGI:MGI:95707|Ensembl:ENSMUSG00000020713|Vega:OTTMUSG00000003423 +14600 Ghr MGI:MGI:95708|Ensembl:ENSMUSG00000055737|Vega:OTTMUSG00000030599 +14601 Ghrh MGI:MGI:95709|Ensembl:ENSMUSG00000027643|Vega:OTTMUSG00000016171 +14602 Ghrhr MGI:MGI:95710|Ensembl:ENSMUSG00000004654|Vega:OTTMUSG00000057887 +14603 Gif MGI:MGI:1202394|Ensembl:ENSMUSG00000024682|Vega:OTTMUSG00000026377 +14605 Tsc22d3 MGI:MGI:1196284|Ensembl:ENSMUSG00000031431|Vega:OTTMUSG00000018845 +14606 Gpin1 MGI:MGI:95711 +14607 Gip MGI:MGI:107504|Ensembl:ENSMUSG00000014351|Vega:OTTMUSG00000001954 +14608 Gpr83 MGI:MGI:95712|Ensembl:ENSMUSG00000031932|Vega:OTTMUSG00000027389 +14609 Gja1 MGI:MGI:95713|Ensembl:ENSMUSG00000050953 +14610 Gja10 MGI:MGI:1339969|Ensembl:ENSMUSG00000051056|Vega:OTTMUSG00000004931 +14611 Gja3 MGI:MGI:95714|Ensembl:ENSMUSG00000048582 +14612 Gja4 MGI:MGI:95715|Ensembl:ENSMUSG00000050234|Vega:OTTMUSG00000009376 +14613 Gja5 MGI:MGI:95716|Ensembl:ENSMUSG00000057123|Vega:OTTMUSG00000022046 +14615 Gjc1 MGI:MGI:95718|Ensembl:ENSMUSG00000034520|Vega:OTTMUSG00000002993 +14616 Gja8 MGI:MGI:99953|Ensembl:ENSMUSG00000049908|Vega:OTTMUSG00000053187 +14617 Gjd2 MGI:MGI:1334209|Ensembl:ENSMUSG00000068615|Vega:OTTMUSG00000015176 +14618 Gjb1 MGI:MGI:95719|Ensembl:ENSMUSG00000047797|Vega:OTTMUSG00000018210 +14619 Gjb2 MGI:MGI:95720|Ensembl:ENSMUSG00000046352|Vega:OTTMUSG00000034674 +14620 Gjb3 MGI:MGI:95721|Ensembl:ENSMUSG00000042367|Vega:OTTMUSG00000009382 +14621 Gjb4 MGI:MGI:95722|Ensembl:ENSMUSG00000046623|Vega:OTTMUSG00000009380 +14622 Gjb5 MGI:MGI:95723|Ensembl:ENSMUSG00000042357|Vega:OTTMUSG00000009375 +14623 Gjb6 MGI:MGI:107588|Ensembl:ENSMUSG00000040055|Vega:OTTMUSG00000034673 +14625 Gykl1 MGI:MGI:891990|Ensembl:ENSMUSG00000053624 +14626 Gk2 MGI:MGI:1329027|Ensembl:ENSMUSG00000050553|Vega:OTTMUSG00000053312 +14628 Ostm1 MGI:MGI:2655574|Ensembl:ENSMUSG00000038280|Vega:OTTMUSG00000019462 +14629 Gclc MGI:MGI:104990|Ensembl:ENSMUSG00000032350|Vega:OTTMUSG00000021059 +14630 Gclm MGI:MGI:104995|Ensembl:ENSMUSG00000028124|Vega:OTTMUSG00000021205 +14632 Gli1 MGI:MGI:95727|Ensembl:ENSMUSG00000025407 +14633 Gli2 MGI:MGI:95728|Ensembl:ENSMUSG00000048402|Vega:OTTMUSG00000034815 +14634 Gli3 MGI:MGI:95729|Ensembl:ENSMUSG00000021318|Vega:OTTMUSG00000024401 +14635 Galk1 MGI:MGI:95730|Ensembl:ENSMUSG00000020766|Vega:OTTMUSG00000003691 +14636 Gln3-1 MGI:MGI:95731 +14645 Glul MGI:MGI:95739|Ensembl:ENSMUSG00000026473|Vega:OTTMUSG00000016462 +14646 Glns-ps1 MGI:MGI:95740 +14651 Hagh MGI:MGI:95745|Ensembl:ENSMUSG00000024158|Vega:OTTMUSG00000026374 +14652 Glp1r MGI:MGI:99571|Ensembl:ENSMUSG00000024027 +14654 Glra1 MGI:MGI:95747|Ensembl:ENSMUSG00000000263|Vega:OTTMUSG00000005698 +14657 Glra4 MGI:MGI:95750|Ensembl:ENSMUSG00000018595|Vega:OTTMUSG00000018721 +14658 Glrb MGI:MGI:95751|Ensembl:ENSMUSG00000028020|Vega:OTTMUSG00000024419 +14659 Glrp1 MGI:MGI:108038|Ensembl:ENSMUSG00000062310|Vega:OTTMUSG00000048259 +14660 Gls MGI:MGI:95752|Ensembl:ENSMUSG00000026103|Vega:OTTMUSG00000021410 +14661 Glud1 MGI:MGI:95753|Ensembl:ENSMUSG00000021794|Vega:OTTMUSG00000030736 +14663 Glycam1 MGI:MGI:95759|Ensembl:ENSMUSG00000022491 +14664 Slc6a9 MGI:MGI:95760|Ensembl:ENSMUSG00000028542|Vega:OTTMUSG00000008656 +14667 Gm2a MGI:MGI:95762|Ensembl:ENSMUSG00000000594|Vega:OTTMUSG00000005683 +14670 Gnl1 MGI:MGI:95764|Ensembl:ENSMUSG00000024429|Vega:OTTMUSG00000037220 +14672 Gna11 MGI:MGI:95766|Ensembl:ENSMUSG00000034781|Vega:OTTMUSG00000030287 +14673 Gna12 MGI:MGI:95767|Ensembl:ENSMUSG00000000149|Vega:OTTMUSG00000024795 +14674 Gna13 MGI:MGI:95768|Ensembl:ENSMUSG00000020611|Vega:OTTMUSG00000003357 +14675 Gna14 MGI:MGI:95769|Ensembl:ENSMUSG00000024697 +14676 Gna15 MGI:MGI:95770|Ensembl:ENSMUSG00000034792|Vega:OTTMUSG00000030451 +14677 Gnai1 MGI:MGI:95771|Ensembl:ENSMUSG00000057614|Vega:OTTMUSG00000053058 +14678 Gnai2 MGI:MGI:95772|Ensembl:ENSMUSG00000032562|Vega:OTTMUSG00000050782 +14679 Gnai3 MGI:MGI:95773|Ensembl:ENSMUSG00000000001|Vega:OTTMUSG00000007197 +14680 Gnal MGI:MGI:95774|Ensembl:ENSMUSG00000024524 +14681 Gnao1 MGI:MGI:95775|Ensembl:ENSMUSG00000031748|Vega:OTTMUSG00000034033 +14682 Gnaq MGI:MGI:95776|Ensembl:ENSMUSG00000024639|Vega:OTTMUSG00000036872 +14683 Gnas MGI:MGI:95777|Ensembl:ENSMUSG00000027523|Vega:OTTMUSG00000016388 +14685 Gnat1 MGI:MGI:95778|Ensembl:ENSMUSG00000034837|Vega:OTTMUSG00000050785 +14686 Gnat2 MGI:MGI:95779|Ensembl:ENSMUSG00000009108|Vega:OTTMUSG00000007183 +14687 Gnaz MGI:MGI:95780|Ensembl:ENSMUSG00000040009|Vega:OTTMUSG00000033002 +14688 Gnb1 MGI:MGI:95781|Ensembl:ENSMUSG00000029064|Vega:OTTMUSG00000010708 +14693 Gnb2 MGI:MGI:95784|Ensembl:ENSMUSG00000029713|Vega:OTTMUSG00000016277 +14694 Rack1 MGI:MGI:101849|Ensembl:ENSMUSG00000020372|Vega:OTTMUSG00000005526 +14695 Gnb3 MGI:MGI:95785|Ensembl:ENSMUSG00000023439|Vega:OTTMUSG00000027058 +14696 Gnb4 MGI:MGI:104581|Ensembl:ENSMUSG00000027669|Vega:OTTMUSG00000016427 +14697 Gnb5 MGI:MGI:101848|Ensembl:ENSMUSG00000032192|Vega:OTTMUSG00000062797 +14698 gnd MGI:MGI:95786 +14699 Gngt1 MGI:MGI:109165|Ensembl:ENSMUSG00000029663|Vega:OTTMUSG00000034241 +14700 Gng10 MGI:MGI:1336169|Ensembl:ENSMUSG00000038607|Vega:OTTMUSG00000007631 +14701 Gng12 MGI:MGI:1336171|Ensembl:ENSMUSG00000036402|Vega:OTTMUSG00000022979 +14702 Gng2 MGI:MGI:102705|Ensembl:ENSMUSG00000043004|Vega:OTTMUSG00000034627 +14703 Gng2-ps1 MGI:MGI:1336164 +14704 Gng3 MGI:MGI:102704|Ensembl:ENSMUSG00000071658 +14705 Bscl2 MGI:MGI:1298392|Ensembl:ENSMUSG00000071657|Vega:OTTMUSG00000034930 +14706 Gng4 MGI:MGI:102703|Ensembl:ENSMUSG00000021303|Vega:OTTMUSG00000029824 +14707 Gng5 MGI:MGI:109164|Ensembl:ENSMUSG00000068523|Vega:OTTMUSG00000029572 +14708 Gng7 MGI:MGI:95787|Ensembl:ENSMUSG00000048240|Vega:OTTMUSG00000030294 +14709 Gng8 MGI:MGI:109163|Ensembl:ENSMUSG00000063594|Vega:OTTMUSG00000058173 +14710 Gngt2 MGI:MGI:893584|Ensembl:ENSMUSG00000038811|Vega:OTTMUSG00000001754 +14711 Gnmt MGI:MGI:1202304|Ensembl:ENSMUSG00000002769|Vega:OTTMUSG00000026384 +14712 Gnpat MGI:MGI:1343460|Ensembl:ENSMUSG00000031985|Vega:OTTMUSG00000031119 +14714 Gnrh1 MGI:MGI:95789|Ensembl:ENSMUSG00000015812 +14715 Gnrhr MGI:MGI:95790|Ensembl:ENSMUSG00000029255|Vega:OTTMUSG00000025622 +14718 Got1 MGI:MGI:95791|Ensembl:ENSMUSG00000025190|Vega:OTTMUSG00000023608 +14719 Got2 MGI:MGI:95792|Ensembl:ENSMUSG00000031672|Vega:OTTMUSG00000016488 +14720 Got2-ps1 MGI:MGI:104721 +14722 gp MGI:MGI:95793 +14723 Gp1ba MGI:MGI:1333744|Ensembl:ENSMUSG00000050675|Vega:OTTMUSG00000006072 +14724 Gp1bb MGI:MGI:107852|Ensembl:ENSMUSG00000050761 +14725 Lrp2 MGI:MGI:95794|Ensembl:ENSMUSG00000027070|Vega:OTTMUSG00000012988 +14726 Pdpn MGI:MGI:103098|Ensembl:ENSMUSG00000028583|Vega:OTTMUSG00000010162 +14727 Lilr4b MGI:MGI:102702|Ensembl:ENSMUSG00000112023 +14728 Lilrb4a MGI:MGI:102701|Ensembl:ENSMUSG00000062593|Ensembl:ENSMUSG00000112148 +14729 Gp5 MGI:MGI:1096363|Ensembl:ENSMUSG00000047953 +14731 Gpaa1 MGI:MGI:1202392|Ensembl:ENSMUSG00000022561|Vega:OTTMUSG00000035761 +14732 Gpam MGI:MGI:109162|Ensembl:ENSMUSG00000024978|Vega:OTTMUSG00000033406 +14733 Gpc1 MGI:MGI:1194891|Ensembl:ENSMUSG00000034220|Vega:OTTMUSG00000048573 +14734 Gpc3 MGI:MGI:104903|Ensembl:ENSMUSG00000055653|Vega:OTTMUSG00000017333 +14735 Gpc4 MGI:MGI:104902|Ensembl:ENSMUSG00000031119|Vega:OTTMUSG00000017330 +14738 Gpr12 MGI:MGI:101909|Ensembl:ENSMUSG00000041468|Vega:OTTMUSG00000055165 +14739 S1pr2 MGI:MGI:99569|Ensembl:ENSMUSG00000043895|Vega:OTTMUSG00000063028 +14744 Gpr65 MGI:MGI:108031|Ensembl:ENSMUSG00000021886 +14745 Lpar1 MGI:MGI:108429|Ensembl:ENSMUSG00000038668|Vega:OTTMUSG00000007519 +14747 Cmklr1 MGI:MGI:109603|Ensembl:ENSMUSG00000042190|Vega:OTTMUSG00000025812 +14748 Gpr3 MGI:MGI:101908|Ensembl:ENSMUSG00000049649|Vega:OTTMUSG00000010474 +14751 Gpi1 MGI:MGI:95797|Ensembl:ENSMUSG00000036427|Vega:OTTMUSG00000008382 +14755 Pigq MGI:MGI:1333114|Ensembl:ENSMUSG00000025728|Vega:OTTMUSG00000033060 +14756 Gpld1 MGI:MGI:106604|Ensembl:ENSMUSG00000021340|Vega:OTTMUSG00000000734 +14758 Gpm6b MGI:MGI:107672|Ensembl:ENSMUSG00000031342|Vega:OTTMUSG00000019536 +14760 Gpr19 MGI:MGI:892973|Ensembl:ENSMUSG00000032641|Vega:OTTMUSG00000024355 +14761 Gpr27 MGI:MGI:1202299|Ensembl:ENSMUSG00000072875|Vega:OTTMUSG00000057659 +14762 Gpr33 MGI:MGI:1277106|Ensembl:ENSMUSG00000035148|Vega:OTTMUSG00000033689 +14763 Gpr37 MGI:MGI:1313297|Ensembl:ENSMUSG00000039904|Vega:OTTMUSG00000056018 +14764 Ptgdr2 MGI:MGI:1330275|Ensembl:ENSMUSG00000034117|Vega:OTTMUSG00000046867 +14765 Gpr50 MGI:MGI:1333877|Ensembl:ENSMUSG00000056380|Vega:OTTMUSG00000017811 +14766 Adgrg1 MGI:MGI:1340051|Ensembl:ENSMUSG00000031785|Vega:OTTMUSG00000061709 +14767 Nmur1 MGI:MGI:1341898|Ensembl:ENSMUSG00000026237|Vega:OTTMUSG00000022669 +14768 Lancl1 MGI:MGI:1336997|Ensembl:ENSMUSG00000026000|Vega:OTTMUSG00000021584 +14772 Grk4 MGI:MGI:95801|Ensembl:ENSMUSG00000052783|Vega:OTTMUSG00000023169 +14773 Grk5 MGI:MGI:109161|Ensembl:ENSMUSG00000003228 +14775 Gpx1 MGI:MGI:104887|Ensembl:ENSMUSG00000063856|Vega:OTTMUSG00000050754 +14776 Gpx2 MGI:MGI:106609|Ensembl:ENSMUSG00000042808 +14777 Gpx2-ps1 MGI:MGI:106627 +14778 Gpx3 MGI:MGI:105102|Ensembl:ENSMUSG00000018339|Vega:OTTMUSG00000006337 +14780 Gpx5 MGI:MGI:104886|Ensembl:ENSMUSG00000004344|Vega:OTTMUSG00000000743 +14781 gr MGI:MGI:95803 +14782 Gsr MGI:MGI:95804|Ensembl:ENSMUSG00000031584|Vega:OTTMUSG00000016634 +14783 Grb10 MGI:MGI:103232|Ensembl:ENSMUSG00000020176|Vega:OTTMUSG00000005165 +14784 Grb2 MGI:MGI:95805|Ensembl:ENSMUSG00000059923|Vega:OTTMUSG00000003535 +14786 Grb7 MGI:MGI:102683|Ensembl:ENSMUSG00000019312|Vega:OTTMUSG00000006361 +14787 Rhpn1 MGI:MGI:1098783|Ensembl:ENSMUSG00000022580|Vega:OTTMUSG00000028092 +14788 Gpr162 MGI:MGI:1315214|Ensembl:ENSMUSG00000038390|Vega:OTTMUSG00000056674 +14789 P3h3 MGI:MGI:1315208|Ensembl:ENSMUSG00000023191|Vega:OTTMUSG00000028990 +14790 Grcc10 MGI:MGI:1315201|Ensembl:ENSMUSG00000072772|Vega:OTTMUSG00000023121 +14791 Emg1 MGI:MGI:1315195|Ensembl:ENSMUSG00000004268|Vega:OTTMUSG00000023581 +14792 Lpcat3 MGI:MGI:1315211|Ensembl:ENSMUSG00000004270|Vega:OTTMUSG00000023580 +14793 Cdca3 MGI:MGI:1315198|Ensembl:ENSMUSG00000023505|Vega:OTTMUSG00000024338 +14794 Spsb2 MGI:MGI:1315199|Ensembl:ENSMUSG00000038451|Vega:OTTMUSG00000022963 +14797 Aes MGI:MGI:95806|Ensembl:ENSMUSG00000054452 +14798 gri MGI:MGI:95807 +14799 Gria1 MGI:MGI:95808|Ensembl:ENSMUSG00000020524|Vega:OTTMUSG00000005703 +14800 Gria2 MGI:MGI:95809|Ensembl:ENSMUSG00000033981|Vega:OTTMUSG00000051468 +14802 Gria4 MGI:MGI:95811|Ensembl:ENSMUSG00000025892|Vega:OTTMUSG00000061694 +14803 Grid1 MGI:MGI:95812|Ensembl:ENSMUSG00000041078|Vega:OTTMUSG00000033220 +14804 Grid2 MGI:MGI:95813|Ensembl:ENSMUSG00000071424|Vega:OTTMUSG00000034292 +14805 Grik1 MGI:MGI:95814|Ensembl:ENSMUSG00000022935|Vega:OTTMUSG00000060488 +14806 Grik2 MGI:MGI:95815|Ensembl:ENSMUSG00000056073 +14807 Grik3 MGI:MGI:95816|Ensembl:ENSMUSG00000001985|Vega:OTTMUSG00000009249 +14809 Grik5 MGI:MGI:95818|Ensembl:ENSMUSG00000003378|Vega:OTTMUSG00000058241 +14810 Grin1 MGI:MGI:95819|Ensembl:ENSMUSG00000026959|Vega:OTTMUSG00000011933 +14811 Grin2a MGI:MGI:95820|Ensembl:ENSMUSG00000059003|Vega:OTTMUSG00000016264 +14812 Grin2b MGI:MGI:95821|Ensembl:ENSMUSG00000030209|Vega:OTTMUSG00000016356 +14813 Grin2c MGI:MGI:95822|Ensembl:ENSMUSG00000020734|Vega:OTTMUSG00000003665 +14814 Grin2d MGI:MGI:95823|Ensembl:ENSMUSG00000002771|Vega:OTTMUSG00000022308 +14815 Nr3c1 MGI:MGI:95824|Ensembl:ENSMUSG00000024431|Vega:OTTMUSG00000023975 +14816 Grm1 MGI:MGI:1351338|Ensembl:ENSMUSG00000019828|Vega:OTTMUSG00000016273 +14823 Grm8 MGI:MGI:1351345|Ensembl:ENSMUSG00000024211|Vega:OTTMUSG00000021285 +14824 Grn MGI:MGI:95832|Ensembl:ENSMUSG00000034708|Vega:OTTMUSG00000002816 +14825 Cxcl1 MGI:MGI:108068|Ensembl:ENSMUSG00000029380|Vega:OTTMUSG00000016842 +14827 Pdia3 MGI:MGI:95834|Ensembl:ENSMUSG00000027248|Vega:OTTMUSG00000015325 +14828 Hspa5 MGI:MGI:95835|Ensembl:ENSMUSG00000026864|Vega:OTTMUSG00000012014 +14829 Grpr MGI:MGI:95836|Ensembl:ENSMUSG00000031364|Vega:OTTMUSG00000019504 +14835 gs MGI:MGI:95840 +14836 Gsc MGI:MGI:95841|Ensembl:ENSMUSG00000021095|Vega:OTTMUSG00000021487 +14840 Gsg1 MGI:MGI:1194499|Ensembl:ENSMUSG00000030206|Vega:OTTMUSG00000023084 +14841 Haspin MGI:MGI:1194498|Ensembl:ENSMUSG00000050107|Vega:OTTMUSG00000006123 +14842 Gsx1 MGI:MGI:95842|Ensembl:ENSMUSG00000053129|Vega:OTTMUSG00000024587 +14843 Gsx2 MGI:MGI:95843|Ensembl:ENSMUSG00000035946|Vega:OTTMUSG00000024574 +14852 Gspt1 MGI:MGI:1316728|Ensembl:ENSMUSG00000062203|Vega:OTTMUSG00000035233 +14853 Gspt2 MGI:MGI:1316727|Ensembl:ENSMUSG00000071723|Vega:OTTMUSG00000018134 +14854 Gss MGI:MGI:95852|Ensembl:ENSMUSG00000027610|Vega:OTTMUSG00000016106 +14857 Gsta1 MGI:MGI:1095417|Ensembl:ENSMUSG00000074183|Vega:OTTMUSG00000031890 +14858 Gsta2 MGI:MGI:95863|Ensembl:ENSMUSG00000057933|Vega:OTTMUSG00000031004 +14859 Gsta3 MGI:MGI:95856|Ensembl:ENSMUSG00000025934|Vega:OTTMUSG00000026333 +14860 Gsta4 MGI:MGI:1309515|Ensembl:ENSMUSG00000032348|Vega:OTTMUSG00000062950 +14862 Gstm1 MGI:MGI:95860|Ensembl:ENSMUSG00000058135|Vega:OTTMUSG00000007188 +14863 Gstm2 MGI:MGI:95861|Ensembl:ENSMUSG00000040562|Vega:OTTMUSG00000007189 +14864 Gstm3 MGI:MGI:106026|Ensembl:ENSMUSG00000004038|Vega:OTTMUSG00000007193 +14865 Gstm4 MGI:MGI:95862|Ensembl:ENSMUSG00000027890|Vega:OTTMUSG00000007184 +14866 Gstm5 MGI:MGI:1309466|Ensembl:ENSMUSG00000004032|Vega:OTTMUSG00000035923 +14867 Gstm6 MGI:MGI:1309467|Ensembl:ENSMUSG00000068762|Vega:OTTMUSG00000007100 +14869 Gstp2 MGI:MGI:95864|Ensembl:ENSMUSG00000038155|Vega:OTTMUSG00000046063 +14870 Gstp1 MGI:MGI:95865|Ensembl:ENSMUSG00000060803|Vega:OTTMUSG00000046062 +14871 Gstt1 MGI:MGI:107379|Ensembl:ENSMUSG00000001663|Vega:OTTMUSG00000026319 +14872 Gstt2 MGI:MGI:106188|Ensembl:ENSMUSG00000033318 +14873 Gsto1 MGI:MGI:1342273|Ensembl:ENSMUSG00000025068|Vega:OTTMUSG00000028264 +14874 Gstz1 MGI:MGI:1341859|Ensembl:ENSMUSG00000021033 +14879 Gtayu1 MGI:MGI:1100493 +14880 Gtayu2 MGI:MGI:1100490 +14882 Gtayu5 MGI:MGI:1100489 +14883 Gtayu6 MGI:MGI:1100487 +14884 Gtf2h1 MGI:MGI:1277216|Ensembl:ENSMUSG00000006599|Vega:OTTMUSG00000024398 +14885 Gtf2h4 MGI:MGI:1338799|Ensembl:ENSMUSG00000001524|Vega:OTTMUSG00000034602 +14886 Gtf2i MGI:MGI:1202722|Ensembl:ENSMUSG00000060261|Vega:OTTMUSG00000036983 +14894 Cfap20 MGI:MGI:107428|Ensembl:ENSMUSG00000031796|Vega:OTTMUSG00000061744 +14897 Trip12 MGI:MGI:1309481|Ensembl:ENSMUSG00000026219|Vega:OTTMUSG00000048005 +14904 Gtpbp1 MGI:MGI:109443|Ensembl:ENSMUSG00000042535 +14910 Gt(ROSA)26Sor MGI:MGI:104735|Ensembl:ENSMUSG00000086429 +14911 Thumpd3 MGI:MGI:1277973|Ensembl:ENSMUSG00000030264|Vega:OTTMUSG00000023628 +14912 Nkx6-2 MGI:MGI:1352738|Ensembl:ENSMUSG00000041309|Vega:OTTMUSG00000024503 +14913 Guca1a MGI:MGI:102770|Ensembl:ENSMUSG00000023982 +14915 Guca2a MGI:MGI:102738|Ensembl:ENSMUSG00000023247|Vega:OTTMUSG00000009463 +14916 Guca2b MGI:MGI:1270851|Ensembl:ENSMUSG00000032978|Vega:OTTMUSG00000009464 +14917 Gucy2c MGI:MGI:106903|Ensembl:ENSMUSG00000042638|Vega:OTTMUSG00000033823 +14918 Gucy2d MGI:MGI:106030|Ensembl:ENSMUSG00000074003|Vega:OTTMUSG00000058862 +14919 Gucy2e MGI:MGI:105123|Ensembl:ENSMUSG00000020890|Vega:OTTMUSG00000005963 +14923 Guk1 MGI:MGI:95871|Ensembl:ENSMUSG00000020444|Vega:OTTMUSG00000005783 +14924 Magi1 MGI:MGI:1203522|Ensembl:ENSMUSG00000045095|Vega:OTTMUSG00000057755 +14933 Gk MGI:MGI:106594|Ensembl:ENSMUSG00000025059|Vega:OTTMUSG00000017916 +14934 Gypa MGI:MGI:95880|Ensembl:ENSMUSG00000051839|Vega:OTTMUSG00000061330 +14936 Gys1 MGI:MGI:101805|Ensembl:ENSMUSG00000003865|Vega:OTTMUSG00000023845 +14938 Gzma MGI:MGI:109266|Ensembl:ENSMUSG00000023132 +14939 Gzmb MGI:MGI:109267|Ensembl:ENSMUSG00000015437 +14940 Gzmc MGI:MGI:109256|Ensembl:ENSMUSG00000079186 +14941 Gzmd MGI:MGI:109255|Ensembl:ENSMUSG00000059256|Vega:OTTMUSG00000034670 +14942 Gzme MGI:MGI:109265|Ensembl:ENSMUSG00000022156 +14943 Gzmf MGI:MGI:109254|Ensembl:ENSMUSG00000015441 +14944 Gzmg MGI:MGI:109253|Ensembl:ENSMUSG00000040284 +14945 Gzmk MGI:MGI:1298232|Ensembl:ENSMUSG00000042385|Vega:OTTMUSG00000027683 +14950 H13 MGI:MGI:95886|Ensembl:ENSMUSG00000019188|Vega:OTTMUSG00000015824 +14955 H19 MGI:MGI:95891|Ensembl:ENSMUSG00000000031 +14957 Hist1h1d MGI:MGI:107502|Ensembl:ENSMUSG00000052565|Vega:OTTMUSG00000000553 +14958 H1f0 MGI:MGI:95893|Ensembl:ENSMUSG00000096210 +14960 H2-Aa MGI:MGI:95895|Ensembl:ENSMUSG00000036594|Vega:OTTMUSG00000037121 +14961 H2-Ab1 MGI:MGI:103070|Ensembl:ENSMUSG00000073421|Vega:OTTMUSG00000037120 +14962 Cfb MGI:MGI:105975|Ensembl:ENSMUSG00000090231|Vega:OTTMUSG00000034004 +14963 H2-Bl MGI:MGI:892004|Ensembl:ENSMUSG00000073406|Vega:OTTMUSG00000037291 +14964 H2-D1 MGI:MGI:95896|Ensembl:ENSMUSG00000073411|Vega:OTTMUSG00000037094 +14967 H2-D4 MGI:MGI:95899 +14969 H2-Eb1 MGI:MGI:95901|Ensembl:ENSMUSG00000060586|Vega:OTTMUSG00000037123 +14972 H2-K1 MGI:MGI:95904|Ensembl:ENSMUSG00000061232|Vega:OTTMUSG00000037104 +14976 Pfdn6 MGI:MGI:95908|Ensembl:ENSMUSG00000024309|Vega:OTTMUSG00000037082 +14977 Slc39a7 MGI:MGI:95909|Ensembl:ENSMUSG00000024327|Vega:OTTMUSG00000035430 +14979 H2-Ke6 MGI:MGI:95911|Ensembl:ENSMUSG00000073422|Vega:OTTMUSG00000035431 +14980 H2-L MGI:MGI:95912 +14985 H2-M10.1 MGI:MGI:1276522|Ensembl:ENSMUSG00000024448|Vega:OTTMUSG00000014942 +14990 H2-M2 MGI:MGI:95914|Ensembl:ENSMUSG00000016283|Vega:OTTMUSG00000037432 +14991 H2-M3 MGI:MGI:95915|Ensembl:ENSMUSG00000016206|Vega:OTTMUSG00000037377 +14992 H2-M4-ps MGI:MGI:95916 +14994 H2-M6-ps MGI:MGI:95918 +14995 H2-M7-ps MGI:MGI:95919 +14997 H2-M9 MGI:MGI:1276570|Ensembl:ENSMUSG00000067201|Vega:OTTMUSG00000014939 +14998 H2-DMa MGI:MGI:95921|Ensembl:ENSMUSG00000037649|Vega:OTTMUSG00000037115 +14999 H2-DMb1 MGI:MGI:95922|Ensembl:ENSMUSG00000079547|Vega:OTTMUSG00000037116 +15000 H2-DMb2 MGI:MGI:95923|Ensembl:ENSMUSG00000037548|Vega:OTTMUSG00000037091 +15001 H2-Oa MGI:MGI:95924|Ensembl:ENSMUSG00000024334|Vega:OTTMUSG00000037090 +15002 H2-Ob MGI:MGI:95925|Ensembl:ENSMUSG00000041538|Vega:OTTMUSG00000037093 +15003 H2-Pa MGI:MGI:105314 +15004 H2-Pb MGI:MGI:95926 +15006 H2-Q1 MGI:MGI:95928|Ensembl:ENSMUSG00000079507|Vega:OTTMUSG00000037097 +15007 H2-Q10 MGI:MGI:95929|Ensembl:ENSMUSG00000067235|Vega:OTTMUSG00000037234 +15013 H2-Q2 MGI:MGI:95931|Ensembl:ENSMUSG00000091705|Vega:OTTMUSG00000037101 +15015 H2-Q4 MGI:MGI:95933|Ensembl:ENSMUSG00000035929|Vega:OTTMUSG00000037138 +15016 H2-Q5 MGI:MGI:95934|Ensembl:ENSMUSG00000055413 +15018 H2-Q7 MGI:MGI:95936|Ensembl:ENSMUSG00000060550|Vega:OTTMUSG00000037191 +15019 H2-Q8 MGI:MGI:95937 +15023 H2-T1 MGI:MGI:95941 +15024 H2-T10 MGI:MGI:95942|Ensembl:ENSMUSG00000079491 +15027 H2-T13 MGI:MGI:95945 +15033 H2-T18 MGI:MGI:95950 +15039 H2-T22 MGI:MGI:95956|Ensembl:ENSMUSG00000056116|Vega:OTTMUSG00000014954 +15040 H2-T23 MGI:MGI:95957|Ensembl:ENSMUSG00000067212|Vega:OTTMUSG00000014955 +15042 H2-T24 MGI:MGI:95958|Ensembl:ENSMUSG00000053835|Vega:OTTMUSG00000014957 +15043 H2-T3 MGI:MGI:95959|Ensembl:ENSMUSG00000054128|Vega:OTTMUSG00000014949 +15051 H2-T9 MGI:MGI:95965 +15061 Ifi44l MGI:MGI:95975|Ensembl:ENSMUSG00000039146|Vega:OTTMUSG00000053619 +15064 Mr1 MGI:MGI:1195463|Ensembl:ENSMUSG00000026471|Vega:OTTMUSG00000049823 +15077 Hist2h3c1 MGI:MGI:2448355|Ensembl:ENSMUSG00000093769|Vega:OTTMUSG00000021930 +15078 H3f3a MGI:MGI:1097686|Ensembl:ENSMUSG00000060743|Vega:OTTMUSG00000021525 +15079 H3f3a-ps1 MGI:MGI:1101782 +15080 H3f3a-ps2 MGI:MGI:1101758 +15081 H3f3b MGI:MGI:1101768|Ensembl:ENSMUSG00000016559|Vega:OTTMUSG00000003689 +15101 H60a MGI:MGI:1306817 +15107 Hadh MGI:MGI:96009|Ensembl:ENSMUSG00000027984|Vega:OTTMUSG00000028850 +15108 Hsd17b10 MGI:MGI:1333871|Ensembl:ENSMUSG00000025260|Vega:OTTMUSG00000019648 +15109 Hal MGI:MGI:96010|Ensembl:ENSMUSG00000020017|Vega:OTTMUSG00000030965 +15110 Hand1 MGI:MGI:103577|Ensembl:ENSMUSG00000037335|Vega:OTTMUSG00000005713 +15111 Hand2 MGI:MGI:103580|Ensembl:ENSMUSG00000038193|Vega:OTTMUSG00000046275 +15112 Hao1 MGI:MGI:96011|Ensembl:ENSMUSG00000027261|Vega:OTTMUSG00000015450 +15114 Hap1 MGI:MGI:1261831|Ensembl:ENSMUSG00000006930|Vega:OTTMUSG00000006280 +15115 Hars MGI:MGI:108087|Ensembl:ENSMUSG00000001380 +15116 Has1 MGI:MGI:106590|Ensembl:ENSMUSG00000003665 +15117 Has2 MGI:MGI:107821|Ensembl:ENSMUSG00000022367|Vega:OTTMUSG00000036745 +15118 Has3 MGI:MGI:109599|Ensembl:ENSMUSG00000031910|Vega:OTTMUSG00000042123 +15120 hb MGI:MGI:107756 +15121 Hba MGI:MGI:96014 +15122 Hba-a1 MGI:MGI:96015|Ensembl:ENSMUSG00000069919|Vega:OTTMUSG00000005377 +15124 Hba-ps3 MGI:MGI:96017 +15126 Hba-x MGI:MGI:96019|Ensembl:ENSMUSG00000055609|Vega:OTTMUSG00000005373 +15127 Hbb MGI:MGI:96020 +15128 Hbb-ar MGI:MGI:102559 +15129 Hbb-b1 MGI:MGI:96021 +15130 Hbb-b2 MGI:MGI:96022 +15131 Hbb-bh0 MGI:MGI:96023 +15132 Hbb-bh1 MGI:MGI:96024|Ensembl:ENSMUSG00000052217|Vega:OTTMUSG00000019079 +15134 Hbb-bh3 MGI:MGI:96026 +15135 Hbb-y MGI:MGI:96027|Ensembl:ENSMUSG00000052187|Vega:OTTMUSG00000019058 +15139 Hc MGI:MGI:96031|Ensembl:ENSMUSG00000026874|Vega:OTTMUSG00000012274 +15140 Hc1 MGI:MGI:96032 +15141 Hc10 MGI:MGI:96033 +15142 Hc11 MGI:MGI:96034 +15143 Hc12 MGI:MGI:96035 +15144 Hc13 MGI:MGI:96036 +15145 Hc14 MGI:MGI:96037 +15146 Hc15 MGI:MGI:96038 +15147 Hc16 MGI:MGI:96039 +15148 Hc17 MGI:MGI:96040 +15149 Hc18 MGI:MGI:96041 +15150 Hc19 MGI:MGI:96042 +15151 Hc2 MGI:MGI:96043 +15152 Hc3 MGI:MGI:96044 +15153 Hc4 MGI:MGI:96045 +15154 Hc5 MGI:MGI:96046 +15155 Hc6 MGI:MGI:96047 +15156 Hc7 MGI:MGI:96048 +15157 Hc8 MGI:MGI:96049 +15158 Hc9 MGI:MGI:96050 +15159 Hccs MGI:MGI:106911|Ensembl:ENSMUSG00000031352|Vega:OTTMUSG00000019596 +15160 Serpind1 MGI:MGI:96051|Ensembl:ENSMUSG00000022766|Vega:OTTMUSG00000030882 +15161 Hcfc1 MGI:MGI:105942|Ensembl:ENSMUSG00000031386|Vega:OTTMUSG00000017652 +15162 Hck MGI:MGI:96052|Ensembl:ENSMUSG00000003283|Vega:OTTMUSG00000015777 +15163 Hcls1 MGI:MGI:104568|Ensembl:ENSMUSG00000022831|Vega:OTTMUSG00000035773 +15164 Hcm MGI:MGI:96053 +15165 Hcn1 MGI:MGI:1096392|Ensembl:ENSMUSG00000021730|Vega:OTTMUSG00000035649 +15166 Hcn2 MGI:MGI:1298210|Ensembl:ENSMUSG00000020331|Vega:OTTMUSG00000027869 +15168 Hcn3 MGI:MGI:1298211|Ensembl:ENSMUSG00000028051|Vega:OTTMUSG00000025270 +15169 hcp MGI:MGI:96054 +15170 Ptpn6 MGI:MGI:96055|Ensembl:ENSMUSG00000004266|Vega:OTTMUSG00000038210 +15171 Hcrt MGI:MGI:1202306|Ensembl:ENSMUSG00000045471|Vega:OTTMUSG00000002123 +15180 Hcx MGI:MGI:96060 +15181 Gm10093 MGI:MGI:3704479 +15182 Hdac2 MGI:MGI:1097691|Ensembl:ENSMUSG00000019777|Vega:OTTMUSG00000020840 +15183 Hdac3 MGI:MGI:1343091|Ensembl:ENSMUSG00000024454|Vega:OTTMUSG00000017266 +15184 Hdac5 MGI:MGI:1333784|Ensembl:ENSMUSG00000008855|Vega:OTTMUSG00000002621 +15185 Hdac6 MGI:MGI:1333752|Ensembl:ENSMUSG00000031161|Vega:OTTMUSG00000017170 +15186 Hdc MGI:MGI:96062|Ensembl:ENSMUSG00000027360|Vega:OTTMUSG00000015753 +15191 Hdgf MGI:MGI:1194494|Ensembl:ENSMUSG00000004897|Vega:OTTMUSG00000027208 +15192 Hdgfl1 MGI:MGI:1194493|Ensembl:ENSMUSG00000045835|Vega:OTTMUSG00000000625 +15193 Hdgfl2 MGI:MGI:1194492|Ensembl:ENSMUSG00000002833 +15194 Htt MGI:MGI:96067|Ensembl:ENSMUSG00000029104|Vega:OTTMUSG00000023182 +15199 Hebp1 MGI:MGI:1333880|Ensembl:ENSMUSG00000042770|Vega:OTTMUSG00000024159 +15200 Hbegf MGI:MGI:96070|Ensembl:ENSMUSG00000024486 +15201 Hells MGI:MGI:106209|Ensembl:ENSMUSG00000025001|Vega:OTTMUSG00000021232 +15202 Gml2 MGI:MGI:1341831|Ensembl:ENSMUSG00000068600|Vega:OTTMUSG00000045216 +15203 Heph MGI:MGI:1332240|Ensembl:ENSMUSG00000031209|Vega:OTTMUSG00000018531 +15204 Herc2 MGI:MGI:103234|Ensembl:ENSMUSG00000030451|Vega:OTTMUSG00000058856 +15205 Hes1 MGI:MGI:104853|Ensembl:ENSMUSG00000022528|Vega:OTTMUSG00000035113 +15206 Hes2 MGI:MGI:1098624|Ensembl:ENSMUSG00000028940|Vega:OTTMUSG00000010304 +15207 Hes3 MGI:MGI:104877|Ensembl:ENSMUSG00000028946|Vega:OTTMUSG00000010409 +15208 Hes5 MGI:MGI:104876|Ensembl:ENSMUSG00000048001|Vega:OTTMUSG00000010459 +15209 Hesx1 MGI:MGI:96071|Ensembl:ENSMUSG00000040726|Vega:OTTMUSG00000037602 +15211 Hexa MGI:MGI:96073|Ensembl:ENSMUSG00000025232|Vega:OTTMUSG00000063295 +15212 Hexb MGI:MGI:96074|Ensembl:ENSMUSG00000021665 +15213 Hey1 MGI:MGI:1341800|Ensembl:ENSMUSG00000040289|Vega:OTTMUSG00000051396 +15214 Hey2 MGI:MGI:1341884|Ensembl:ENSMUSG00000019789|Vega:OTTMUSG00000038103 +15215 hf MGI:MGI:96075 +15216 Hfe MGI:MGI:109191|Ensembl:ENSMUSG00000006611|Vega:OTTMUSG00000000737 +15218 Foxn1 MGI:MGI:102949|Ensembl:ENSMUSG00000002057|Vega:OTTMUSG00000000142 +15220 Foxq1 MGI:MGI:1298228|Ensembl:ENSMUSG00000038415|Vega:OTTMUSG00000000723 +15221 Foxd3 MGI:MGI:1347473|Ensembl:ENSMUSG00000067261|Vega:OTTMUSG00000007976 +15223 Foxj1 MGI:MGI:1347474|Ensembl:ENSMUSG00000034227|Vega:OTTMUSG00000003841 +15227 Foxf1 MGI:MGI:1347470|Ensembl:ENSMUSG00000042812|Vega:OTTMUSG00000043020 +15228 Foxg1 MGI:MGI:1347464|Ensembl:ENSMUSG00000020950|Vega:OTTMUSG00000021132 +15229 Foxd1 MGI:MGI:1347463|Ensembl:ENSMUSG00000078302|Vega:OTTMUSG00000020973 +15233 Hgd MGI:MGI:96078|Ensembl:ENSMUSG00000022821|Vega:OTTMUSG00000035117 +15234 Hgf MGI:MGI:96079|Ensembl:ENSMUSG00000028864|Vega:OTTMUSG00000055308 +15235 Mst1 MGI:MGI:96080|Ensembl:ENSMUSG00000032591|Vega:OTTMUSG00000033726 +15239 Hgs MGI:MGI:104681|Ensembl:ENSMUSG00000025793|Vega:OTTMUSG00000004240 +15242 Hhex MGI:MGI:96086|Ensembl:ENSMUSG00000024986|Vega:OTTMUSG00000021162 +15244 Hhex-rs3 MGI:MGI:1201389 +15245 Hhip MGI:MGI:1341847|Ensembl:ENSMUSG00000064325|Vega:OTTMUSG00000031006 +15247 Mfsd14a MGI:MGI:1201609|Ensembl:ENSMUSG00000089911|Vega:OTTMUSG00000029518 +15248 Hic1 MGI:MGI:1338010|Ensembl:ENSMUSG00000043099|Vega:OTTMUSG00000006196 +15251 Hif1a MGI:MGI:106918|Ensembl:ENSMUSG00000021109|Vega:OTTMUSG00000019740 +15254 Hint1 MGI:MGI:1321133|Ensembl:ENSMUSG00000020267|Vega:OTTMUSG00000005678 +15257 Hipk1 MGI:MGI:1314873|Ensembl:ENSMUSG00000008730|Vega:OTTMUSG00000024242 +15258 Hipk2 MGI:MGI:1314872|Ensembl:ENSMUSG00000061436|Vega:OTTMUSG00000034370 +15259 Hipk3 MGI:MGI:1314882|Ensembl:ENSMUSG00000027177|Vega:OTTMUSG00000014944 +15260 Hira MGI:MGI:99430|Ensembl:ENSMUSG00000022702|Vega:OTTMUSG00000026265 +15267 Hist2h2aa1 MGI:MGI:96097|Ensembl:ENSMUSG00000064220|Vega:OTTMUSG00000042073 +15268 Hist3 MGI:MGI:96098 +15270 H2afx MGI:MGI:102688|Ensembl:ENSMUSG00000049932|Vega:OTTMUSG00000042356 +15273 Hivep2 MGI:MGI:1338076|Ensembl:ENSMUSG00000015501|Vega:OTTMUSG00000046529 +15275 Hk1 MGI:MGI:96103|Ensembl:ENSMUSG00000037012|Vega:OTTMUSG00000034151 +15277 Hk2 MGI:MGI:1315197|Ensembl:ENSMUSG00000000628|Vega:OTTMUSG00000035991 +15278 Tfb2m MGI:MGI:107937|Ensembl:ENSMUSG00000026492|Vega:OTTMUSG00000022545 +15280 hl MGI:MGI:96106 +15284 Hlx MGI:MGI:96109|Ensembl:ENSMUSG00000039377|Vega:OTTMUSG00000037282 +15285 Mnx1 MGI:MGI:109160|Ensembl:ENSMUSG00000001566|Vega:OTTMUSG00000037528 +15288 Hmbs MGI:MGI:96112|Ensembl:ENSMUSG00000032126|Vega:OTTMUSG00000063256 +15289 Hmgb1 MGI:MGI:96113|Ensembl:ENSMUSG00000066551|Vega:OTTMUSG00000016672 +15290 Hmgb1-rs10 MGI:MGI:104304 +15291 Hmgb1-rs11 MGI:MGI:104303 +15292 Hmgb1-rs12 MGI:MGI:104302 +15293 Hmgb1-rs13 MGI:MGI:104301 +15294 Hmgb1-rs14 MGI:MGI:104300 +15295 Hmgb1-ps3 MGI:MGI:3768539 +15296 Hmgb1-rs16 MGI:MGI:104765 +15298 Hmgb1-rs18 MGI:MGI:104763 +15312 Hmgn1 MGI:MGI:96120|Ensembl:ENSMUSG00000040681|Vega:OTTMUSG00000019978 +15331 Hmgn2 MGI:MGI:96136|Ensembl:ENSMUSG00000003038|Vega:OTTMUSG00000009711 +15352 Gm4739 MGI:MGI:3642984 +15353 Hmg20b MGI:MGI:1341190|Ensembl:ENSMUSG00000020232|Vega:OTTMUSG00000017278 +15354 Hmgb3 MGI:MGI:1098219|Ensembl:ENSMUSG00000015217|Vega:OTTMUSG00000017794 +15356 Hmgcl MGI:MGI:96158|Ensembl:ENSMUSG00000028672|Vega:OTTMUSG00000009847 +15357 Hmgcr MGI:MGI:96159|Ensembl:ENSMUSG00000021670|Vega:OTTMUSG00000035511 +15360 Hmgcs2 MGI:MGI:101939|Ensembl:ENSMUSG00000027875|Vega:OTTMUSG00000026370 +15361 Hmga1 MGI:MGI:96160|Ensembl:ENSMUSG00000046711|Vega:OTTMUSG00000028935 +15364 Hmga2 MGI:MGI:101761|Ensembl:ENSMUSG00000056758|Vega:OTTMUSG00000033206 +15365 Hmga2-ps1 MGI:MGI:106023 +15366 Hmmr MGI:MGI:104667|Ensembl:ENSMUSG00000020330|Vega:OTTMUSG00000005436 +15368 Hmox1 MGI:MGI:96163|Ensembl:ENSMUSG00000005413|Vega:OTTMUSG00000030644 +15369 Hmox2 MGI:MGI:109373|Ensembl:ENSMUSG00000004070|Vega:OTTMUSG00000026637 +15370 Nr4a1 MGI:MGI:1352454|Ensembl:ENSMUSG00000023034 +15371 Hmx1 MGI:MGI:107178|Ensembl:ENSMUSG00000067438|Vega:OTTMUSG00000037283 +15372 Hmx2 MGI:MGI:107159|Ensembl:ENSMUSG00000050100|Vega:OTTMUSG00000037287 +15373 Hmx3 MGI:MGI:107160|Ensembl:ENSMUSG00000040148|Vega:OTTMUSG00000037286 +15374 Jpt1 MGI:MGI:1096361|Ensembl:ENSMUSG00000020737|Vega:OTTMUSG00000003443 +15375 Foxa1 MGI:MGI:1347472|Ensembl:ENSMUSG00000035451 +15376 Foxa2 MGI:MGI:1347476|Ensembl:ENSMUSG00000037025|Vega:OTTMUSG00000015678 +15377 Foxa3 MGI:MGI:1347477|Ensembl:ENSMUSG00000040891|Vega:OTTMUSG00000020440 +15378 Hnf4a MGI:MGI:109128|Ensembl:ENSMUSG00000017950|Vega:OTTMUSG00000001071 +15379 Onecut1 MGI:MGI:1196423|Ensembl:ENSMUSG00000043013|Vega:OTTMUSG00000034722 +15381 Hnrnpc MGI:MGI:107795|Ensembl:ENSMUSG00000060373 +15382 Hnrnpa1 MGI:MGI:104820|Ensembl:ENSMUSG00000046434 +15384 Hnrnpab MGI:MGI:1330294|Ensembl:ENSMUSG00000020358|Vega:OTTMUSG00000005602 +15387 Hnrnpk MGI:MGI:99894|Ensembl:ENSMUSG00000021546|Vega:OTTMUSG00000035894 +15388 Hnrnpl MGI:MGI:104816|Ensembl:ENSMUSG00000015165|Vega:OTTMUSG00000037299 +15394 Hoxa1 MGI:MGI:96170|Ensembl:ENSMUSG00000029844|Vega:OTTMUSG00000018885 +15395 Hoxa10 MGI:MGI:96171|Ensembl:ENSMUSG00000000938|Vega:OTTMUSG00000018886 +15396 Hoxa11 MGI:MGI:96172|Ensembl:ENSMUSG00000038210|Vega:OTTMUSG00000018883 +15397 Hoxa11os MGI:MGI:107208|Ensembl:ENSMUSG00000086427 +15398 Hoxa13 MGI:MGI:96173 +15399 Hoxa2 MGI:MGI:96174|Ensembl:ENSMUSG00000014704|Vega:OTTMUSG00000037358 +15400 Hoxa3 MGI:MGI:96175|Ensembl:ENSMUSG00000079560|Vega:OTTMUSG00000018880 +15401 Hoxa4 MGI:MGI:96176|Ensembl:ENSMUSG00000000942|Vega:OTTMUSG00000018878 +15402 Hoxa5 MGI:MGI:96177|Ensembl:ENSMUSG00000038253|Vega:OTTMUSG00000018868 +15403 Hoxa6 MGI:MGI:96178|Ensembl:ENSMUSG00000043219|Vega:OTTMUSG00000018882 +15404 Hoxa7 MGI:MGI:96179|Ensembl:ENSMUSG00000038236|Vega:OTTMUSG00000018867 +15405 Hoxa9 MGI:MGI:96180|Ensembl:ENSMUSG00000038227|Vega:OTTMUSG00000018873 +15406 Hoxb MGI:MGI:96181 +15407 Hoxb1 MGI:MGI:96182|Ensembl:ENSMUSG00000018973|Vega:OTTMUSG00000001776 +15408 Hoxb13 MGI:MGI:107730|Ensembl:ENSMUSG00000049604|Vega:OTTMUSG00000001955 +15410 Hoxb3 MGI:MGI:96184|Ensembl:ENSMUSG00000048763|Vega:OTTMUSG00000001781 +15412 Hoxb4 MGI:MGI:96185|Ensembl:ENSMUSG00000038692|Vega:OTTMUSG00000001777 +15413 Hoxb5 MGI:MGI:96186|Ensembl:ENSMUSG00000038700|Vega:OTTMUSG00000001987 +15414 Hoxb6 MGI:MGI:96187|Ensembl:ENSMUSG00000000690|Vega:OTTMUSG00000001988 +15415 Hoxb7 MGI:MGI:96188|Ensembl:ENSMUSG00000038721|Vega:OTTMUSG00000001989 +15416 Hoxb8 MGI:MGI:96189|Ensembl:ENSMUSG00000056648|Vega:OTTMUSG00000001990 +15417 Hoxb9 MGI:MGI:96190|Ensembl:ENSMUSG00000020875|Vega:OTTMUSG00000001991 +15421 Hoxc12 MGI:MGI:96194|Ensembl:ENSMUSG00000050328|Vega:OTTMUSG00000037393 +15422 Hoxc13 MGI:MGI:99560|Ensembl:ENSMUSG00000001655|Vega:OTTMUSG00000037392 +15423 Hoxc4 MGI:MGI:96195|Ensembl:ENSMUSG00000075394|Vega:OTTMUSG00000035136 +15424 Hoxc5 MGI:MGI:96196|Ensembl:ENSMUSG00000022485|Vega:OTTMUSG00000037400 +15425 Hoxc6 MGI:MGI:96197|Ensembl:ENSMUSG00000001661|Vega:OTTMUSG00000037399 +15426 Hoxc8 MGI:MGI:96198|Ensembl:ENSMUSG00000001657|Vega:OTTMUSG00000037398 +15427 Hoxc9 MGI:MGI:96199|Ensembl:ENSMUSG00000036139|Vega:OTTMUSG00000037397 +15429 Hoxd1 MGI:MGI:96201|Ensembl:ENSMUSG00000042448|Vega:OTTMUSG00000016601 +15430 Hoxd10 MGI:MGI:96202|Ensembl:ENSMUSG00000050368|Vega:OTTMUSG00000016554 +15431 Hoxd11 MGI:MGI:96203|Ensembl:ENSMUSG00000042499|Vega:OTTMUSG00000016551 +15432 Hoxd12 MGI:MGI:96204|Ensembl:ENSMUSG00000001823|Vega:OTTMUSG00000016555 +15433 Hoxd13 MGI:MGI:96205|Ensembl:ENSMUSG00000001819|Vega:OTTMUSG00000013304 +15434 Hoxd3 MGI:MGI:96207|Ensembl:ENSMUSG00000079277|Vega:OTTMUSG00000045589 +15436 Hoxd4 MGI:MGI:96208|Ensembl:ENSMUSG00000101174|Vega:OTTMUSG00000019164 +15437 Hoxd8 MGI:MGI:96209|Ensembl:ENSMUSG00000027102|Vega:OTTMUSG00000016550 +15438 Hoxd9 MGI:MGI:96210|Ensembl:ENSMUSG00000043342|Vega:OTTMUSG00000016552 +15439 Hp MGI:MGI:96211|Ensembl:ENSMUSG00000031722|Vega:OTTMUSG00000061918 +15441 Hp1bp3 MGI:MGI:109369|Ensembl:ENSMUSG00000028759|Vega:OTTMUSG00000009979 +15442 Hpse MGI:MGI:1343124|Ensembl:ENSMUSG00000035273|Vega:OTTMUSG00000026166 +15443 hpc MGI:MGI:96212 +15444 Hpca MGI:MGI:1336200|Ensembl:ENSMUSG00000028785|Vega:OTTMUSG00000009624 +15445 Hpd MGI:MGI:96213|Ensembl:ENSMUSG00000029445|Vega:OTTMUSG00000026899 +15446 Hpgd MGI:MGI:108085|Ensembl:ENSMUSG00000031613|Vega:OTTMUSG00000060690 +15447 hph1 MGI:MGI:96214 +15448 hph2 MGI:MGI:96215 +15450 Lipc MGI:MGI:96216|Ensembl:ENSMUSG00000032207|Vega:OTTMUSG00000062767 +15451 Hpn MGI:MGI:1196620|Ensembl:ENSMUSG00000001249|Vega:OTTMUSG00000036085 +15452 Hprt MGI:MGI:96217|Ensembl:ENSMUSG00000025630|Vega:OTTMUSG00000017356 +15455 Hpvc1 MGI:MGI:96220 +15458 Hpx MGI:MGI:105112|Ensembl:ENSMUSG00000030895|Vega:OTTMUSG00000060450 +15460 Hr MGI:MGI:96223|Ensembl:ENSMUSG00000022096|Vega:OTTMUSG00000034183 +15461 Hras MGI:MGI:96224|Ensembl:ENSMUSG00000025499|Vega:OTTMUSG00000016471 +15463 Agfg1 MGI:MGI:1333754|Ensembl:ENSMUSG00000026159|Vega:OTTMUSG00000047960 +15464 Hrc MGI:MGI:96226|Ensembl:ENSMUSG00000038239|Vega:OTTMUSG00000023829 +15465 Hrh1 MGI:MGI:107619|Ensembl:ENSMUSG00000053004|Vega:OTTMUSG00000034565 +15466 Hrh2 MGI:MGI:108482|Ensembl:ENSMUSG00000034987|Vega:OTTMUSG00000034187 +15467 Eif2ak1 MGI:MGI:1353448|Ensembl:ENSMUSG00000029613|Vega:OTTMUSG00000025503 +15468 Prmt2 MGI:MGI:1316652|Ensembl:ENSMUSG00000020230|Vega:OTTMUSG00000020177 +15469 Prmt1 MGI:MGI:107846|Ensembl:ENSMUSG00000109324|Vega:OTTMUSG00000020537 +15473 Rida MGI:MGI:1095401|Ensembl:ENSMUSG00000022323|Vega:OTTMUSG00000028006 +15475 hs MGI:MGI:96230 +15476 Hs3st1 MGI:MGI:1201606|Ensembl:ENSMUSG00000051022|Vega:OTTMUSG00000029672 +15478 Hs3st3a1 MGI:MGI:1333861|Ensembl:ENSMUSG00000047759|Vega:OTTMUSG00000005895 +15481 Hspa8 MGI:MGI:105384|Ensembl:ENSMUSG00000015656|Vega:OTTMUSG00000030238 +15482 Hspa1l MGI:MGI:96231|Ensembl:ENSMUSG00000007033|Vega:OTTMUSG00000016296 +15483 Hsd11b1 MGI:MGI:103562|Ensembl:ENSMUSG00000016194|Vega:OTTMUSG00000030692 +15484 Hsd11b2 MGI:MGI:104720|Ensembl:ENSMUSG00000031891|Vega:OTTMUSG00000062049 +15485 Hsd17b1 MGI:MGI:105077|Ensembl:ENSMUSG00000019301|Vega:OTTMUSG00000002687 +15486 Hsd17b2 MGI:MGI:1096386|Ensembl:ENSMUSG00000031844|Vega:OTTMUSG00000061613 +15487 Hsd17b3 MGI:MGI:107177|Ensembl:ENSMUSG00000033122 +15488 Hsd17b4 MGI:MGI:105089|Ensembl:ENSMUSG00000024507|Vega:OTTMUSG00000021126 +15490 Hsd17b7 MGI:MGI:1330808|Ensembl:ENSMUSG00000026675|Vega:OTTMUSG00000020778 +15492 Hsd3b1 MGI:MGI:96233|Ensembl:ENSMUSG00000027871|Vega:OTTMUSG00000006826 +15493 Hsd3b2 MGI:MGI:96234|Ensembl:ENSMUSG00000063730|Vega:OTTMUSG00000006735 +15494 Hsd3b3 MGI:MGI:96235|Ensembl:ENSMUSG00000062410|Vega:OTTMUSG00000006703 +15495 Hsd3b4 MGI:MGI:96236|Ensembl:ENSMUSG00000095143|Vega:OTTMUSG00000054016 +15496 Hsd3b5 MGI:MGI:104645|Ensembl:ENSMUSG00000038092|Vega:OTTMUSG00000054021 +15497 Hsd3b6 MGI:MGI:109598|Ensembl:ENSMUSG00000027869|Vega:OTTMUSG00000006781 +15499 Hsf1 MGI:MGI:96238|Ensembl:ENSMUSG00000022556 +15500 Hsf2 MGI:MGI:96239|Ensembl:ENSMUSG00000019878 +15501 hsh MGI:MGI:1096571 +15502 Dnaja1 MGI:MGI:1270129|Ensembl:ENSMUSG00000028410|Vega:OTTMUSG00000006566 +15504 Dnajb3 MGI:MGI:1306822|Ensembl:ENSMUSG00000081984|Vega:OTTMUSG00000020806 +15505 Hsph1 MGI:MGI:105053|Ensembl:ENSMUSG00000029657|Vega:OTTMUSG00000021374 +15507 Hspb1 MGI:MGI:96240|Ensembl:ENSMUSG00000004951|Vega:OTTMUSG00000024281 +15508 Hsp25-ps1 MGI:MGI:96241 +15510 Hspd1 MGI:MGI:96242|Ensembl:ENSMUSG00000025980|Vega:OTTMUSG00000021770 +15511 Hspa1b MGI:MGI:99517|Ensembl:ENSMUSG00000090877|Vega:OTTMUSG00000037920 +15512 Hspa2 MGI:MGI:96243|Ensembl:ENSMUSG00000059970 +15516 Hsp90ab1 MGI:MGI:96247|Ensembl:ENSMUSG00000023944|Vega:OTTMUSG00000020123 +15519 Hsp90aa1 MGI:MGI:96250|Ensembl:ENSMUSG00000021270|Vega:OTTMUSG00000019766 +15525 Hspa4 MGI:MGI:1342292|Ensembl:ENSMUSG00000020361|Vega:OTTMUSG00000000056 +15526 Hspa9 MGI:MGI:96245|Ensembl:ENSMUSG00000024359|Vega:OTTMUSG00000037646 +15527 Hspa9-ps1 MGI:MGI:96246 +15528 Hspe1 MGI:MGI:104680|Ensembl:ENSMUSG00000073676|Vega:OTTMUSG00000021821 +15529 Sdc2 MGI:MGI:1349165|Ensembl:ENSMUSG00000022261|Vega:OTTMUSG00000027993 +15530 Hspg2 MGI:MGI:96257|Ensembl:ENSMUSG00000028763|Vega:OTTMUSG00000009935 +15531 Ndst1 MGI:MGI:104719|Ensembl:ENSMUSG00000054008 +15547 Trmt2a MGI:MGI:96270|Ensembl:ENSMUSG00000022721|Vega:OTTMUSG00000026007 +15549 htr MGI:MGI:96272 +15550 Htr1a MGI:MGI:96273|Ensembl:ENSMUSG00000021721 +15551 Htr1b MGI:MGI:96274|Ensembl:ENSMUSG00000049511|Vega:OTTMUSG00000044868 +15552 Htr1d MGI:MGI:96276|Ensembl:ENSMUSG00000070687|Vega:OTTMUSG00000009699 +15553 Htr1da MGI:MGI:96277 +15557 Htr1f MGI:MGI:99842|Ensembl:ENSMUSG00000050783 +15558 Htr2a MGI:MGI:109521|Ensembl:ENSMUSG00000034997 +15559 Htr2b MGI:MGI:109323|Ensembl:ENSMUSG00000026228|Vega:OTTMUSG00000033955 +15560 Htr2c MGI:MGI:96281|Ensembl:ENSMUSG00000041380|Vega:OTTMUSG00000018943 +15561 Htr3a MGI:MGI:96282|Ensembl:ENSMUSG00000032269|Vega:OTTMUSG00000063011 +15562 Htr4 MGI:MGI:109246|Ensembl:ENSMUSG00000026322 +15563 Htr5a MGI:MGI:96283|Ensembl:ENSMUSG00000039106|Vega:OTTMUSG00000054148 +15564 Htr5b MGI:MGI:96284|Ensembl:ENSMUSG00000050534|Vega:OTTMUSG00000021025 +15565 Htr6 MGI:MGI:1196627|Ensembl:ENSMUSG00000028747|Vega:OTTMUSG00000009899 +15566 Htr7 MGI:MGI:99841|Ensembl:ENSMUSG00000024798|Vega:OTTMUSG00000035906 +15567 Slc6a4 MGI:MGI:96285|Ensembl:ENSMUSG00000020838|Vega:OTTMUSG00000006240 +15568 Elavl1 MGI:MGI:1100851|Ensembl:ENSMUSG00000040028|Vega:OTTMUSG00000059686 +15569 Elavl2 MGI:MGI:1100887|Ensembl:ENSMUSG00000008489|Vega:OTTMUSG00000007821 +15570 hubb MGI:MGI:96286 +15571 Elavl3 MGI:MGI:109157|Ensembl:ENSMUSG00000003410|Vega:OTTMUSG00000062327 +15572 Elavl4 MGI:MGI:107427|Ensembl:ENSMUSG00000028546|Vega:OTTMUSG00000008498 +15573 hug MGI:MGI:96287 +15574 Hus1 MGI:MGI:1277962|Ensembl:ENSMUSG00000020413|Vega:OTTMUSG00000005146 +15581 hy1 MGI:MGI:96293 +15582 hy2 MGI:MGI:96294 +15586 Hyal1 MGI:MGI:96298|Ensembl:ENSMUSG00000010051|Vega:OTTMUSG00000028838 +15587 Hyal2 MGI:MGI:1196334|Ensembl:ENSMUSG00000010047|Vega:OTTMUSG00000050817 +15600 Iap1-1 MGI:MGI:96307 +15601 Iap1-3 MGI:MGI:1343056 +15731 Iap8-1 MGI:MGI:96310 +15874 Iapp MGI:MGI:96382|Ensembl:ENSMUSG00000041681|Vega:OTTMUSG00000024215 +15890 Iapy-1 MGI:MGI:105116 +15891 Ibsp MGI:MGI:96389|Ensembl:ENSMUSG00000029306|Vega:OTTMUSG00000021399 +15893 Ica1 MGI:MGI:96391|Ensembl:ENSMUSG00000062995|Vega:OTTMUSG00000023181 +15894 Icam1 MGI:MGI:96392|Ensembl:ENSMUSG00000037405|Vega:OTTMUSG00000063048 +15896 Icam2 MGI:MGI:96394|Ensembl:ENSMUSG00000001029|Vega:OTTMUSG00000003420 +15898 Icam5 MGI:MGI:109430|Ensembl:ENSMUSG00000032174|Vega:OTTMUSG00000063057 +15900 Irf8 MGI:MGI:96395|Ensembl:ENSMUSG00000041515|Vega:OTTMUSG00000033858 +15901 Id1 MGI:MGI:96396|Ensembl:ENSMUSG00000042745|Vega:OTTMUSG00000015813 +15902 Id2 MGI:MGI:96397|Ensembl:ENSMUSG00000020644 +15903 Id3 MGI:MGI:96398|Ensembl:ENSMUSG00000007872|Vega:OTTMUSG00000009864 +15904 Id4 MGI:MGI:99414|Ensembl:ENSMUSG00000021379 +15925 Ide MGI:MGI:96412|Ensembl:ENSMUSG00000056999|Vega:OTTMUSG00000029864 +15926 Idh1 MGI:MGI:96413|Ensembl:ENSMUSG00000025950|Vega:OTTMUSG00000021898 +15929 Idh3g MGI:MGI:1099463|Ensembl:ENSMUSG00000002010|Vega:OTTMUSG00000017673 +15930 Ido1 MGI:MGI:96416|Ensembl:ENSMUSG00000031551|Vega:OTTMUSG00000020648 +15931 Ids MGI:MGI:96417|Ensembl:ENSMUSG00000035847|Vega:OTTMUSG00000025736 +15932 Idua MGI:MGI:96418|Ensembl:ENSMUSG00000033540|Vega:OTTMUSG00000027012 +15936 Ier2 MGI:MGI:104815|Ensembl:ENSMUSG00000053560 +15937 Ier3 MGI:MGI:104814|Ensembl:ENSMUSG00000003541|Vega:OTTMUSG00000037405 +15939 Ier5 MGI:MGI:1337072|Ensembl:ENSMUSG00000056708|Vega:OTTMUSG00000049822 +15944 Irgm1 MGI:MGI:107567|Ensembl:ENSMUSG00000046879|Vega:OTTMUSG00000005518 +15945 Cxcl10 MGI:MGI:1352450|Ensembl:ENSMUSG00000034855|Vega:OTTMUSG00000028740 +15950 Ifi203 MGI:MGI:96428|Ensembl:ENSMUSG00000039997|Vega:OTTMUSG00000026980 +15951 Ifi204 MGI:MGI:96429|Ensembl:ENSMUSG00000073489|Vega:OTTMUSG00000033920 +15953 Ifi47 MGI:MGI:99448|Ensembl:ENSMUSG00000078920|Vega:OTTMUSG00000005538 +15957 Ifit1 MGI:MGI:99450|Ensembl:ENSMUSG00000034459|Vega:OTTMUSG00000016647 +15958 Ifit2 MGI:MGI:99449|Ensembl:ENSMUSG00000045932|Vega:OTTMUSG00000016643 +15959 Ifit3 MGI:MGI:1101055|Ensembl:ENSMUSG00000074896|Vega:OTTMUSG00000016645 +15962 Ifna1 MGI:MGI:107668|Ensembl:ENSMUSG00000095498|Vega:OTTMUSG00000007695 +15964 Ifna11 MGI:MGI:109210|Ensembl:ENSMUSG00000100549|Vega:OTTMUSG00000011274 +15965 Ifna2 MGI:MGI:107666|Ensembl:ENSMUSG00000078354|Vega:OTTMUSG00000011279 +15967 Ifna4 MGI:MGI:107664|Ensembl:ENSMUSG00000070904|Vega:OTTMUSG00000011263 +15968 Ifna5 MGI:MGI:107663|Ensembl:ENSMUSG00000096682|Vega:OTTMUSG00000011264 +15969 Ifna6 MGI:MGI:107662|Ensembl:ENSMUSG00000101252|Vega:OTTMUSG00000011288 +15970 Ifna7 MGI:MGI:107661|Ensembl:ENSMUSG00000100713|Vega:OTTMUSG00000011286 +15972 Ifna9 MGI:MGI:107659|Ensembl:ENSMUSG00000095270|Vega:OTTMUSG00000007667 +15974 Ifnab MGI:MGI:1097683|Ensembl:ENSMUSG00000100079|Vega:OTTMUSG00000011271 +15975 Ifnar1 MGI:MGI:107658|Ensembl:ENSMUSG00000022967|Vega:OTTMUSG00000027185 +15976 Ifnar2 MGI:MGI:1098243|Ensembl:ENSMUSG00000022971|Vega:OTTMUSG00000040135 +15977 Ifnb1 MGI:MGI:107657|Ensembl:ENSMUSG00000048806|Vega:OTTMUSG00000007654 +15978 Ifng MGI:MGI:107656|Ensembl:ENSMUSG00000055170 +15979 Ifngr1 MGI:MGI:107655|Ensembl:ENSMUSG00000020009|Vega:OTTMUSG00000035345 +15980 Ifngr2 MGI:MGI:107654|Ensembl:ENSMUSG00000022965|Vega:OTTMUSG00000028337 +15982 Ifrd1 MGI:MGI:1316717|Ensembl:ENSMUSG00000001627|Vega:OTTMUSG00000035474 +15983 Ifrd2 MGI:MGI:1316708|Ensembl:ENSMUSG00000010048|Vega:OTTMUSG00000050667 +15985 Cd79b MGI:MGI:96431|Ensembl:ENSMUSG00000040592 +16000 Igf1 MGI:MGI:96432|Ensembl:ENSMUSG00000020053|Vega:OTTMUSG00000031391 +16001 Igf1r MGI:MGI:96433|Ensembl:ENSMUSG00000005533|Vega:OTTMUSG00000059602 +16002 Igf2 MGI:MGI:96434|Ensembl:ENSMUSG00000048583|Vega:OTTMUSG00000035324 +16004 Igf2r MGI:MGI:96435|Ensembl:ENSMUSG00000023830|Vega:OTTMUSG00000034915 +16005 Igfals MGI:MGI:107973|Ensembl:ENSMUSG00000046070 +16006 Igfbp1 MGI:MGI:96436|Ensembl:ENSMUSG00000020429|Vega:OTTMUSG00000005136 +16007 Cyr61 MGI:MGI:88613|Ensembl:ENSMUSG00000028195|Vega:OTTMUSG00000055191 +16008 Igfbp2 MGI:MGI:96437|Ensembl:ENSMUSG00000039323|Vega:OTTMUSG00000029573 +16009 Igfbp3 MGI:MGI:96438|Ensembl:ENSMUSG00000020427|Vega:OTTMUSG00000005135 +16010 Igfbp4 MGI:MGI:96439|Ensembl:ENSMUSG00000017493|Vega:OTTMUSG00000006441 +16011 Igfbp5 MGI:MGI:96440|Ensembl:ENSMUSG00000026185|Vega:OTTMUSG00000017306 +16012 Igfbp6 MGI:MGI:96441|Ensembl:ENSMUSG00000023046|Vega:OTTMUSG00000035011 +16016 Ighg2b MGI:MGI:96445|IMGT/GENE-DB:IGHG2B +16017 Ighg1 MGI:MGI:96446|IMGT/GENE-DB:IGHG1 +16019 Ighm MGI:MGI:96448|IMGT/GENE-DB:IGHM +16020 Igh-7 MGI:MGI:96449 +16021 Igh-8 MGI:MGI:96450 +16031 Igh-Ia MGI:MGI:106608 +16033 Igh-J MGI:MGI:96461 +16043 Igh-Sa1 MGI:MGI:96471 +16049 Igh-V MGI:MGI:96477 +16050 Igh-V10 MGI:MGI:96478 +16051 Igh-V11 MGI:MGI:96479 +16053 Igh-V15 MGI:MGI:106606 +16055 Igh-V31 MGI:MGI:96480 +16057 Igh-V3609N MGI:MGI:96482 +16058 Igh-V3660 MGI:MGI:96483 +16059 Igh-V7183 MGI:MGI:96484 +16061 Igh-VJ558 MGI:MGI:96486 +16062 Igh-VJ606 MGI:MGI:96487 +16065 Igh-VS107 MGI:MGI:96490 +16068 Il18bp MGI:MGI:1333800|Ensembl:ENSMUSG00000070427|Vega:OTTMUSG00000061180 +16069 Jchain MGI:MGI:96493|Ensembl:ENSMUSG00000067149|Vega:OTTMUSG00000036864 +16071 Igkc MGI:MGI:96495|IMGT/GENE-DB:IGKC +16073 Igk-J MGI:MGI:96497 +16080 Igk-V MGI:MGI:96499 +16081 Igk-V1 MGI:MGI:96500 +16087 Igk-V12/13 MGI:MGI:103031 +16097 Igk-V20 MGI:MGI:96506 +16098 Igkv1-117 MGI:MGI:4439721|IMGT/GENE-DB:IGKV1-117 +16113 Igk-V24 MGI:MGI:96510 +16114 Igk-V28 MGI:MGI:96511 +16118 Igk-V34 MGI:MGI:96515 +16121 Igk-V4 MGI:MGI:96516 +16122 Igk-V5 MGI:MGI:96517 +16129 Igk-V9 MGI:MGI:96519 +16136 Igll1 MGI:MGI:96529|Ensembl:ENSMUSG00000075370|Vega:OTTMUSG00000025624 +16142 Iglv1 MGI:MGI:96530|IMGT/GENE-DB:IGLV1 +16145 Igtp MGI:MGI:107729|Ensembl:ENSMUSG00000078853|Vega:OTTMUSG00000005727 +16147 Ihh MGI:MGI:96533|Ensembl:ENSMUSG00000006538|Vega:OTTMUSG00000048255 +16149 Cd74 MGI:MGI:96534|Ensembl:ENSMUSG00000024610 +16150 Ikbkb MGI:MGI:1338071|Ensembl:ENSMUSG00000031537|Vega:OTTMUSG00000020581 +16151 Ikbkg MGI:MGI:1338074|Ensembl:ENSMUSG00000004221|Vega:OTTMUSG00000017732 +16153 Il10 MGI:MGI:96537|Ensembl:ENSMUSG00000016529|Vega:OTTMUSG00000016630 +16154 Il10ra MGI:MGI:96538|Ensembl:ENSMUSG00000032089|Vega:OTTMUSG00000042168 +16155 Il10rb MGI:MGI:109380|Ensembl:ENSMUSG00000022969|Vega:OTTMUSG00000028329 +16156 Il11 MGI:MGI:107613|Ensembl:ENSMUSG00000004371|Vega:OTTMUSG00000040054 +16157 Il11ra1 MGI:MGI:107426|Ensembl:ENSMUSG00000073889|Vega:OTTMUSG00000006681 +16158 Il11ra2 MGI:MGI:109123|Ensembl:ENSMUSG00000078735 +16159 Il12a MGI:MGI:96539|Ensembl:ENSMUSG00000027776|Vega:OTTMUSG00000051459 +16160 Il12b MGI:MGI:96540|Ensembl:ENSMUSG00000004296|Vega:OTTMUSG00000005468 +16161 Il12rb1 MGI:MGI:104579|Ensembl:ENSMUSG00000000791|Vega:OTTMUSG00000061579 +16162 Il12rb2 MGI:MGI:1270861|Ensembl:ENSMUSG00000018341|Vega:OTTMUSG00000029293 +16163 Il13 MGI:MGI:96541|Ensembl:ENSMUSG00000020383|Vega:OTTMUSG00000005641 +16164 Il13ra1 MGI:MGI:105052|Ensembl:ENSMUSG00000017057|Vega:OTTMUSG00000017214 +16165 Il13ra2 MGI:MGI:1277954|Ensembl:ENSMUSG00000031289|Vega:OTTMUSG00000018962 +16168 Il15 MGI:MGI:103014|Ensembl:ENSMUSG00000031712|Vega:OTTMUSG00000061372 +16169 Il15ra MGI:MGI:104644|Ensembl:ENSMUSG00000023206|Vega:OTTMUSG00000011178 +16170 Il16 MGI:MGI:1270855|Ensembl:ENSMUSG00000001741|Vega:OTTMUSG00000027337 +16171 Il17a MGI:MGI:107364|Ensembl:ENSMUSG00000025929|Vega:OTTMUSG00000033825 +16172 Il17ra MGI:MGI:107399|Ensembl:ENSMUSG00000002897|Vega:OTTMUSG00000056821 +16173 Il18 MGI:MGI:107936|Ensembl:ENSMUSG00000039217|Vega:OTTMUSG00000063071 +16174 Il18rap MGI:MGI:1338888|Ensembl:ENSMUSG00000026068|Vega:OTTMUSG00000034788 +16175 Il1a MGI:MGI:96542|Ensembl:ENSMUSG00000027399|Vega:OTTMUSG00000015415 +16176 Il1b MGI:MGI:96543|Ensembl:ENSMUSG00000027398|Vega:OTTMUSG00000015509 +16177 Il1r1 MGI:MGI:96545|Ensembl:ENSMUSG00000026072|Vega:OTTMUSG00000050518 +16178 Il1r2 MGI:MGI:96546|Ensembl:ENSMUSG00000026073|Vega:OTTMUSG00000050443 +16179 Irak1 MGI:MGI:107420|Ensembl:ENSMUSG00000031392|Vega:OTTMUSG00000017687 +16180 Il1rap MGI:MGI:104975|Ensembl:ENSMUSG00000022514|Vega:OTTMUSG00000036972 +16181 Il1rn MGI:MGI:96547|Ensembl:ENSMUSG00000026981|Vega:OTTMUSG00000011966 +16182 Il18r1 MGI:MGI:105383|Ensembl:ENSMUSG00000026070|Vega:OTTMUSG00000050472 +16183 Il2 MGI:MGI:96548|Ensembl:ENSMUSG00000027720|Vega:OTTMUSG00000007347 +16184 Il2ra MGI:MGI:96549|Ensembl:ENSMUSG00000026770|Vega:OTTMUSG00000011179 +16185 Il2rb MGI:MGI:96550|Ensembl:ENSMUSG00000068227 +16186 Il2rg MGI:MGI:96551|Ensembl:ENSMUSG00000031304|Vega:OTTMUSG00000018211 +16187 Il3 MGI:MGI:96552|Ensembl:ENSMUSG00000018914|Vega:OTTMUSG00000005664 +16188 Il3ra MGI:MGI:96553|Ensembl:ENSMUSG00000068758 +16189 Il4 MGI:MGI:96556|Ensembl:ENSMUSG00000000869|Vega:OTTMUSG00000005642 +16190 Il4ra MGI:MGI:105367|Ensembl:ENSMUSG00000030748|Vega:OTTMUSG00000058201 +16191 Il5 MGI:MGI:96557|Ensembl:ENSMUSG00000036117|Vega:OTTMUSG00000005643 +16192 Il5ra MGI:MGI:96558|Ensembl:ENSMUSG00000005364|Vega:OTTMUSG00000056402 +16193 Il6 MGI:MGI:96559|Ensembl:ENSMUSG00000025746|Vega:OTTMUSG00000054480 +16194 Il6ra MGI:MGI:105304|Ensembl:ENSMUSG00000027947|Vega:OTTMUSG00000052883 +16195 Il6st MGI:MGI:96560|Ensembl:ENSMUSG00000021756|Vega:OTTMUSG00000044624 +16196 Il7 MGI:MGI:96561|Ensembl:ENSMUSG00000040329|Vega:OTTMUSG00000051379 +16197 Il7r MGI:MGI:96562|Ensembl:ENSMUSG00000003882 +16198 Il9 MGI:MGI:96563|Ensembl:ENSMUSG00000021538 +16199 Il9r MGI:MGI:96564|Ensembl:ENSMUSG00000020279|Vega:OTTMUSG00000006344 +16201 Ilf3 MGI:MGI:1339973|Ensembl:ENSMUSG00000032178|Vega:OTTMUSG00000063342 +16202 Ilk MGI:MGI:1195267|Ensembl:ENSMUSG00000030890|Vega:OTTMUSG00000025598 +16204 Fabp6 MGI:MGI:96565|Ensembl:ENSMUSG00000020405|Vega:OTTMUSG00000005454 +16205 Gimap1 MGI:MGI:109368|Ensembl:ENSMUSG00000090019|Vega:OTTMUSG00000026921 +16206 Lrig1 MGI:MGI:107935|Ensembl:ENSMUSG00000030029|Vega:OTTMUSG00000024528 +16210 Impact MGI:MGI:1098233|Ensembl:ENSMUSG00000024423 +16211 Kpnb1 MGI:MGI:107532|Ensembl:ENSMUSG00000001440|Vega:OTTMUSG00000002303 +16212 In(1)10Rk-d MGI:MGI:1333466 +16213 In(1)10Rk-p MGI:MGI:103599 +16214 In(1)12Rk-d MGI:MGI:1333467 +16215 In(1)12Rk-p MGI:MGI:103600 +16216 In(1)1Icg-d MGI:MGI:1333463 +16217 In(1)1Icg-p MGI:MGI:103595 +16218 In(1)1Lub-d MGI:MGI:1333464 +16219 In(1)1Lub-p MGI:MGI:103596 +16220 In(1)1Rk-d MGI:MGI:1333465 +16221 In(1)1Rk-p MGI:MGI:103597 +16222 In(1)23Rk MGI:MGI:103601 +16223 In(1)24Rk-d MGI:MGI:1333468 +16224 In(1)24Rk-p MGI:MGI:103602 +16225 In(1)38Rk MGI:MGI:103603 +16226 In(1)46Rk MGI:MGI:103604 +16227 In(1)49Rk MGI:MGI:103605 +16228 In(1)5H MGI:MGI:103598 +16229 In(10)17Rk-d MGI:MGI:1333490 +16231 In(10)42Rk MGI:MGI:104056 +16232 In(10)57Rk MGI:MGI:104057 +16233 In(10)6Rk-d MGI:MGI:1333489 +16234 In(10)6Rk-p MGI:MGI:104054 +16235 In(10)7H MGI:MGI:107212 +16236 In(11)20Rk MGI:MGI:104097 +16237 In(11)2Dn-d MGI:MGI:1333491 +16238 In(11)2Dn-p MGI:MGI:104096 +16239 In(12)25Rk-d MGI:MGI:1333492 +16240 In(12)25Rk-p MGI:MGI:104126 +16241 In(13)31Rk-d MGI:MGI:1333493 +16242 In(13)31Rk-p MGI:MGI:104140 +16243 In(13)43Rk MGI:MGI:104141 +16244 In(13)50Rk MGI:MGI:104142 +16245 In(14)22Rk-d MGI:MGI:1333495 +16246 In(14)22Rk-p MGI:MGI:104168 +16247 In(14)36Rk MGI:MGI:104169 +16248 In(14)54Rk MGI:MGI:104170 +16249 In(15)18Rk-d MGI:MGI:1333497 +16250 In(15)18Rk-p MGI:MGI:104182 +16251 In(15)21Rk-d MGI:MGI:1333498 +16252 In(15)21Rk-p MGI:MGI:104183 +16253 In(15)2Rl MGI:MGI:104180 +16254 In(15)35Rk MGI:MGI:104184 +16255 In(15)4H-d MGI:MGI:1333496 +16256 In(15)4H-p MGI:MGI:104181 +16257 In(16)51Rk MGI:MGI:104199 +16258 In(17)1t MGI:MGI:104225 +16259 In(17)2t MGI:MGI:104226 +16260 In(17)3t MGI:MGI:104227 +16261 In(17)4t MGI:MGI:104228 +16262 In(19)37Rk MGI:MGI:104237 +16263 In(2)19Rk-d MGI:MGI:1333472 +16264 In(2)19Rk-p MGI:MGI:103670 +16265 In(2)2H-d MGI:MGI:1333469 +16266 In(2)2H-p MGI:MGI:103667 +16267 In(2)3Dn-d MGI:MGI:1333470 +16268 In(2)3Dn-p MGI:MGI:103668 +16269 In(2)40Rk MGI:MGI:103671 +16270 In(2)45Rk MGI:MGI:103672 +16271 In(2)58Rk MGI:MGI:103673 +16272 In(2)5Rk-d MGI:MGI:1333471 +16273 In(2)5Rk-p MGI:MGI:103669 +16274 In(3)11Rk-d MGI:MGI:1333473 +16275 In(3)11Rk-p MGI:MGI:103740 +16276 In(3)15Rk-d MGI:MGI:1333474 +16277 In(3)15Rk-p MGI:MGI:103741 +16278 In(3)55Rk-d MGI:MGI:1333475 +16279 In(3)55Rk-p MGI:MGI:103742 +16280 In(4)1By MGI:MGI:103778 +16281 In(4)1Dn-d MGI:MGI:1333476 +16282 In(4)1Dn-p MGI:MGI:103779 +16283 In(4)28Rk-d MGI:MGI:1333477 +16284 In(4)28Rk-p MGI:MGI:103780 +16285 In(4)32Rk-d MGI:MGI:1333478 +16286 In(4)32Rk-p MGI:MGI:103781 +16287 In(4)56Rk MGI:MGI:103782 +16288 In(5)2Rk-d MGI:MGI:1333479 +16289 In(5)2Rk-p MGI:MGI:103833 +16290 In(5)30Rk-d MGI:MGI:1333481 +16291 In(5)30Rk-p MGI:MGI:103835 +16292 In(5)33Rk-d MGI:MGI:1333482 +16293 In(5)33Rk-p MGI:MGI:103836 +16294 In(5)6H-d MGI:MGI:103832 +16295 In(5)9Rk-d MGI:MGI:1333480 +16296 In(5)9Rk-p MGI:MGI:103834 +16297 In(6)47Rk MGI:MGI:103887 +16298 In(6)48Rk MGI:MGI:103888 +16299 In(6.15)Rb1Ald1Wa MGI:MGI:103889 +16300 In(6.15)Rb1Ald1Wa MGI:MGI:103890 +16301 In(7)13Rk-d MGI:MGI:1333484 +16302 In(7)13Rk-p MGI:MGI:103937 +16303 In(8)14Rk-d MGI:MGI:1333485 +16304 In(8)14Rk-p MGI:MGI:103986 +16305 In(8)16Rk-d MGI:MGI:1333486 +16306 In(8)16Rk-p MGI:MGI:103987 +16307 In(8)34Rk MGI:MGI:103988 +16308 In(8pq)1Rl MGI:MGI:103989 +16309 In(9)26Rk-d MGI:MGI:1333488 +16310 In(9)26Rk-p MGI:MGI:104020 +16311 In(9)39Rk MGI:MGI:104021 +16312 In(9)Rl-d MGI:MGI:1333487 +16313 In(9)Rl-p MGI:MGI:104019 +16314 In(X)1H MGI:MGI:104238 +16315 In(X)3H-d MGI:MGI:1333499 +16316 In(X)3H-p MGI:MGI:104239 +16317 In(YLS)Lub MGI:MGI:104287 +16319 Incenp MGI:MGI:1313288|Ensembl:ENSMUSG00000024660 +16322 Inha MGI:MGI:96569|Ensembl:ENSMUSG00000032968|Vega:OTTMUSG00000019422 +16323 Inhba MGI:MGI:96570|Ensembl:ENSMUSG00000041324 +16324 Inhbb MGI:MGI:96571|Ensembl:ENSMUSG00000037035|Vega:OTTMUSG00000034781 +16325 Inhbc MGI:MGI:105932|Ensembl:ENSMUSG00000025405 +16326 Inhbe MGI:MGI:109269|Ensembl:ENSMUSG00000047492 +16328 Cep250 MGI:MGI:108084|Ensembl:ENSMUSG00000038241|Vega:OTTMUSG00000015999 +16329 Inpp1 MGI:MGI:104848|Ensembl:ENSMUSG00000026102|Vega:OTTMUSG00000026596 +16330 Inpp5b MGI:MGI:103257|Ensembl:ENSMUSG00000028894|Vega:OTTMUSG00000009176 +16331 Inpp5d MGI:MGI:107357|Ensembl:ENSMUSG00000026288|Vega:OTTMUSG00000035865 +16332 Inppl1 MGI:MGI:1333787|Ensembl:ENSMUSG00000032737|Vega:OTTMUSG00000046069 +16333 Ins1 MGI:MGI:96572|Ensembl:ENSMUSG00000035804 +16334 Ins2 MGI:MGI:96573|Ensembl:ENSMUSG00000000215|Vega:OTTMUSG00000018794 +16336 Insl3 MGI:MGI:108427|Ensembl:ENSMUSG00000079019|Vega:OTTMUSG00000021110 +16337 Insr MGI:MGI:96575|Ensembl:ENSMUSG00000005534|Vega:OTTMUSG00000031438 +16341 Eif3e MGI:MGI:99257|Ensembl:ENSMUSG00000022336 +16342 Eif3s6-ps1 MGI:MGI:103203 +16343 Eif3s6-ps2 MGI:MGI:103204 +16344 Eif3s6-ps3 MGI:MGI:103213 +16345 Eif3s6-ps4 MGI:MGI:103210 +16348 Invs MGI:MGI:1335082|Ensembl:ENSMUSG00000028344|Vega:OTTMUSG00000006844 +16351 Ipp MGI:MGI:96581|Ensembl:ENSMUSG00000028696|Vega:OTTMUSG00000009405 +16352 ipv MGI:MGI:96582 +16353 Ipw MGI:MGI:892030|Ensembl:ENSMUSG00000100826 +16362 Irf1 MGI:MGI:96590|Ensembl:ENSMUSG00000018899|Vega:OTTMUSG00000005648 +16363 Irf2 MGI:MGI:96591|Ensembl:ENSMUSG00000031627|Vega:OTTMUSG00000059880 +16364 Irf4 MGI:MGI:1096873|Ensembl:ENSMUSG00000021356|Vega:OTTMUSG00000000722 +16365 Acod1 MGI:MGI:103206|Ensembl:ENSMUSG00000022126|Vega:OTTMUSG00000035543 +16367 Irs1 MGI:MGI:99454|Ensembl:ENSMUSG00000055980|Vega:OTTMUSG00000016464 +16369 Irs3 MGI:MGI:1194882|Ensembl:ENSMUSG00000047182|Vega:OTTMUSG00000054603 +16370 Irs4 MGI:MGI:1338009|Ensembl:ENSMUSG00000054667|Vega:OTTMUSG00000019737 +16371 Irx1 MGI:MGI:1197515|Ensembl:ENSMUSG00000060969|Vega:OTTMUSG00000040082 +16372 Irx2 MGI:MGI:1197526|Ensembl:ENSMUSG00000001504|Vega:OTTMUSG00000036811 +16373 Irx3 MGI:MGI:1197522|Ensembl:ENSMUSG00000031734|Vega:OTTMUSG00000040086 +16374 Is(1;11)2H MGI:MGI:103606 +16375 Is(1;11)2H MGI:MGI:103607 +16376 Is(17;In2)1Gso MGI:MGI:104230 +16377 Is(17;In2)1Gso MGI:MGI:104231 +16378 Is(17;In2)1Gso MGI:MGI:104229 +16379 Is(7;1)40H MGI:MGI:103938 +16380 Is(7;1)40H MGI:MGI:103939 +16381 Is(7;InX)1Neu MGI:MGI:103940 +16382 Is(7;InX)1Neu MGI:MGI:103941 +16383 Is(7;InX)1Neu MGI:MGI:103942 +16384 Is(HSR;1)1Icg MGI:MGI:103608 +16385 Is(HSR;1)1Lub MGI:MGI:103610 +16386 Is(HSR;1)2Icg MGI:MGI:103609 +16387 Is(In;5)1H MGI:MGI:103837 +16388 Is(In7;X)1Ct MGI:MGI:103944 +16389 Is(In7;X)1Ct MGI:MGI:103943 +16391 Irf9 MGI:MGI:107587|Ensembl:ENSMUSG00000002325|Vega:OTTMUSG00000029027 +16392 Isl1 MGI:MGI:101791|Ensembl:ENSMUSG00000042258|Vega:OTTMUSG00000039739 +16396 Itch MGI:MGI:1202301|Ensembl:ENSMUSG00000027598|Vega:OTTMUSG00000016008 +16398 Itga2 MGI:MGI:96600|Ensembl:ENSMUSG00000015533 +16399 Itga2b MGI:MGI:96601|Ensembl:ENSMUSG00000034664|Vega:OTTMUSG00000002857 +16400 Itga3 MGI:MGI:96602|Ensembl:ENSMUSG00000001507|Vega:OTTMUSG00000001616 +16401 Itga4 MGI:MGI:96603|Ensembl:ENSMUSG00000027009|Vega:OTTMUSG00000013313 +16402 Itga5 MGI:MGI:96604|Ensembl:ENSMUSG00000000555|Vega:OTTMUSG00000062577 +16403 Itga6 MGI:MGI:96605|Ensembl:ENSMUSG00000027111|Vega:OTTMUSG00000013266 +16404 Itga7 MGI:MGI:102700|Ensembl:ENSMUSG00000025348 +16407 Itgae MGI:MGI:1298377|Ensembl:ENSMUSG00000005947|Vega:OTTMUSG00000006122 +16408 Itgal MGI:MGI:96606|Ensembl:ENSMUSG00000030830|Vega:OTTMUSG00000031314 +16409 Itgam MGI:MGI:96607|Ensembl:ENSMUSG00000030786|Ensembl:ENSMUSG00000108596|Vega:OTTMUSG00000030928|Vega:OTTMUSG00000058643 +16410 Itgav MGI:MGI:96608|Ensembl:ENSMUSG00000027087|Vega:OTTMUSG00000013360 +16411 Itgax MGI:MGI:96609|Ensembl:ENSMUSG00000030789|Vega:OTTMUSG00000058667 +16412 Itgb1 MGI:MGI:96610|Ensembl:ENSMUSG00000025809|Vega:OTTMUSG00000034034 +16413 Itgb1bp1 MGI:MGI:1306802|Ensembl:ENSMUSG00000062352|Vega:OTTMUSG00000037686 +16414 Itgb2 MGI:MGI:96611|Ensembl:ENSMUSG00000000290|Vega:OTTMUSG00000019985 +16415 Itgb2l MGI:MGI:1277979|Ensembl:ENSMUSG00000000157|Vega:OTTMUSG00000020391 +16416 Itgb3 MGI:MGI:96612|Ensembl:ENSMUSG00000020689|Vega:OTTMUSG00000003177 +16418 Eif6 MGI:MGI:1196288|Ensembl:ENSMUSG00000027613|Vega:OTTMUSG00000016192 +16419 Itgb5 MGI:MGI:96614|Ensembl:ENSMUSG00000022817|Vega:OTTMUSG00000028487 +16420 Itgb6 MGI:MGI:96615|Ensembl:ENSMUSG00000026971|Vega:OTTMUSG00000012790 +16421 Itgb7 MGI:MGI:96616|Ensembl:ENSMUSG00000001281|Vega:OTTMUSG00000030863 +16423 Cd47 MGI:MGI:96617|Ensembl:ENSMUSG00000055447|Vega:OTTMUSG00000014965 +16424 Itih1 MGI:MGI:96618|Ensembl:ENSMUSG00000006529|Vega:OTTMUSG00000035524 +16425 Itih2 MGI:MGI:96619|Ensembl:ENSMUSG00000037254|Vega:OTTMUSG00000011191 +16426 Itih3 MGI:MGI:96620|Ensembl:ENSMUSG00000006522|Vega:OTTMUSG00000035523 +16427 Itih4 MGI:MGI:109536|Ensembl:ENSMUSG00000021922|Vega:OTTMUSG00000026366 +16428 Itk MGI:MGI:96621|Ensembl:ENSMUSG00000020395|Vega:OTTMUSG00000005493 +16429 Itln1 MGI:MGI:1333831|Ensembl:ENSMUSG00000038209|Vega:OTTMUSG00000036496 +16430 Stt3a MGI:MGI:105124|Ensembl:ENSMUSG00000032116|Vega:OTTMUSG00000031806 +16431 Itm2a MGI:MGI:107706|Ensembl:ENSMUSG00000031239|Vega:OTTMUSG00000018150 +16432 Itm2b MGI:MGI:1309517|Ensembl:ENSMUSG00000022108 +16433 Cuzd1 MGI:MGI:1202881|Ensembl:ENSMUSG00000040205|Vega:OTTMUSG00000045956 +16434 Itpa MGI:MGI:96622|Ensembl:ENSMUSG00000074797|Vega:OTTMUSG00000015497 +16438 Itpr1 MGI:MGI:96623|Ensembl:ENSMUSG00000030102|Vega:OTTMUSG00000056439 +16439 Itpr2 MGI:MGI:99418|Ensembl:ENSMUSG00000030287|Vega:OTTMUSG00000025625 +16440 Itpr3 MGI:MGI:96624|Ensembl:ENSMUSG00000042644|Vega:OTTMUSG00000031360 +16443 Itsn1 MGI:MGI:1338069|Ensembl:ENSMUSG00000022957|Vega:OTTMUSG00000021345 +16447 Ivl MGI:MGI:96626|Ensembl:ENSMUSG00000049128|Vega:OTTMUSG00000051843 +16449 Jag1 MGI:MGI:1095416|Ensembl:ENSMUSG00000027276|Vega:OTTMUSG00000015560 +16450 Jag2 MGI:MGI:1098270|Ensembl:ENSMUSG00000002799 +16451 Jak1 MGI:MGI:96628|Ensembl:ENSMUSG00000028530|Vega:OTTMUSG00000008208 +16452 Jak2 MGI:MGI:96629|Ensembl:ENSMUSG00000024789 +16453 Jak3 MGI:MGI:99928|Ensembl:ENSMUSG00000031805|Vega:OTTMUSG00000021111 +16454 jb MGI:MGI:96630 +16456 F11r MGI:MGI:1321398|Ensembl:ENSMUSG00000038235|Vega:OTTMUSG00000021724 +16461 jd MGI:MGI:96634 +16462 jdf MGI:MGI:96635 +16465 jg MGI:MGI:96638 +16467 Atcay MGI:MGI:2448730|Ensembl:ENSMUSG00000034958|Vega:OTTMUSG00000030319 +16468 Jarid2 MGI:MGI:104813|Ensembl:ENSMUSG00000038518|Vega:OTTMUSG00000037582 +16469 Jrk MGI:MGI:106214|Ensembl:ENSMUSG00000046380|Vega:OTTMUSG00000023665 +16470 Ush1g MGI:MGI:2450757|Ensembl:ENSMUSG00000045288|Vega:OTTMUSG00000003746 +16473 jt MGI:MGI:96644 +16475 Ajuba MGI:MGI:1341886|Ensembl:ENSMUSG00000022178 +16476 Jun MGI:MGI:96646|Ensembl:ENSMUSG00000052684|Vega:OTTMUSG00000008035 +16477 Junb MGI:MGI:96647|Ensembl:ENSMUSG00000052837|Vega:OTTMUSG00000061397 +16478 Jund MGI:MGI:96648|Ensembl:ENSMUSG00000071076|Vega:OTTMUSG00000061455 +16480 Jup MGI:MGI:96650|Ensembl:ENSMUSG00000001552|Vega:OTTMUSG00000006276 +16483 Kap MGI:MGI:96653|Ensembl:ENSMUSG00000032758|Vega:OTTMUSG00000056997 +16485 Kcna1 MGI:MGI:96654|Ensembl:ENSMUSG00000047976|Vega:OTTMUSG00000056736 +16490 Kcna2 MGI:MGI:96659|Ensembl:ENSMUSG00000040724|Vega:OTTMUSG00000052942 +16491 Kcna3 MGI:MGI:96660|Ensembl:ENSMUSG00000047959|Vega:OTTMUSG00000056409 +16492 Kcna4 MGI:MGI:96661|Ensembl:ENSMUSG00000042604|Vega:OTTMUSG00000015041 +16493 Kcna5 MGI:MGI:96662|Ensembl:ENSMUSG00000045534|Vega:OTTMUSG00000056734 +16494 Kcna6 MGI:MGI:96663|Ensembl:ENSMUSG00000038077|Vega:OTTMUSG00000022444 +16495 Kcna7 MGI:MGI:96664|Ensembl:ENSMUSG00000038201|Vega:OTTMUSG00000059406 +16497 Kcnab1 MGI:MGI:109155|Ensembl:ENSMUSG00000027827|Vega:OTTMUSG00000034877 +16498 Kcnab2 MGI:MGI:109239|Ensembl:ENSMUSG00000028931|Vega:OTTMUSG00000033817 +16499 Kcnab3 MGI:MGI:1336208|Ensembl:ENSMUSG00000018470|Vega:OTTMUSG00000005965 +16500 Kcnb1 MGI:MGI:96666|Ensembl:ENSMUSG00000050556|Vega:OTTMUSG00000001150 +16502 Kcnc1 MGI:MGI:96667|Ensembl:ENSMUSG00000058975|Vega:OTTMUSG00000034762 +16504 Kcnc3 MGI:MGI:96669|Ensembl:ENSMUSG00000062785|Vega:OTTMUSG00000021883 +16506 Kcnd1 MGI:MGI:96671|Ensembl:ENSMUSG00000009731|Vega:OTTMUSG00000017926 +16508 Kcnd2 MGI:MGI:102663|Ensembl:ENSMUSG00000060882|Vega:OTTMUSG00000036888 +16509 Kcne1 MGI:MGI:96673|Ensembl:ENSMUSG00000039639 +16510 Kcnh1 MGI:MGI:1341721|Ensembl:ENSMUSG00000058248|Vega:OTTMUSG00000024518 +16511 Kcnh2 MGI:MGI:1341722|Ensembl:ENSMUSG00000038319|Vega:OTTMUSG00000024115 +16512 Kcnh3 MGI:MGI:1341723|Ensembl:ENSMUSG00000037579 +16513 Kcnj10 MGI:MGI:1194504|Ensembl:ENSMUSG00000044708|Vega:OTTMUSG00000050148 +16514 Kcnj11 MGI:MGI:107501|Ensembl:ENSMUSG00000096146|Vega:OTTMUSG00000058298 +16515 Kcnj12 MGI:MGI:108495|Ensembl:ENSMUSG00000042529|Vega:OTTMUSG00000005827 +16516 Kcnj15 MGI:MGI:1310000|Ensembl:ENSMUSG00000062609|Vega:OTTMUSG00000019964 +16517 Kcnj16 MGI:MGI:1314842|Ensembl:ENSMUSG00000051497|Vega:OTTMUSG00000003322 +16518 Kcnj2 MGI:MGI:104744|Ensembl:ENSMUSG00000041695|Vega:OTTMUSG00000003324 +16519 Kcnj3 MGI:MGI:104742|Ensembl:ENSMUSG00000026824|Vega:OTTMUSG00000015447 +16520 Kcnj4 MGI:MGI:104743|Ensembl:ENSMUSG00000044216 +16521 Kcnj5 MGI:MGI:104755|Ensembl:ENSMUSG00000032034|Vega:OTTMUSG00000062895 +16522 Kcnj6 MGI:MGI:104781|Ensembl:ENSMUSG00000043301 +16523 Kcnj8 MGI:MGI:1100508|Ensembl:ENSMUSG00000030247|Vega:OTTMUSG00000057136 +16524 Kcnj9 MGI:MGI:108007|Ensembl:ENSMUSG00000038026|Vega:OTTMUSG00000050096 +16525 Kcnk1 MGI:MGI:109322|Ensembl:ENSMUSG00000033998|Vega:OTTMUSG00000061597 +16526 Kcnk2 MGI:MGI:109366|Ensembl:ENSMUSG00000037624|Vega:OTTMUSG00000051040 +16527 Kcnk3 MGI:MGI:1100509|Ensembl:ENSMUSG00000049265|Vega:OTTMUSG00000054481 +16528 Kcnk4 MGI:MGI:1298234|Ensembl:ENSMUSG00000024957 +16529 Kcnk5 MGI:MGI:1336175|Ensembl:ENSMUSG00000023243 +16530 Kcnk7 MGI:MGI:1341841|Ensembl:ENSMUSG00000024936|Vega:OTTMUSG00000028874 +16531 Kcnma1 MGI:MGI:99923|Ensembl:ENSMUSG00000063142|Vega:OTTMUSG00000045153 +16532 Kcnu1 MGI:MGI:1202300|Ensembl:ENSMUSG00000031576|Vega:OTTMUSG00000031857 +16533 Kcnmb1 MGI:MGI:1334203|Ensembl:ENSMUSG00000020155|Vega:OTTMUSG00000005401 +16534 Kcnn4 MGI:MGI:1277957|Ensembl:ENSMUSG00000054342|Vega:OTTMUSG00000058076 +16535 Kcnq1 MGI:MGI:108083|Ensembl:ENSMUSG00000009545|Vega:OTTMUSG00000046376 +16536 Kcnq2 MGI:MGI:1309503|Ensembl:ENSMUSG00000016346|Vega:OTTMUSG00000016558 +16538 Kcns1 MGI:MGI:1197019|Ensembl:ENSMUSG00000040164|Vega:OTTMUSG00000001173 +16539 Kcns2 MGI:MGI:1197011|Ensembl:ENSMUSG00000050963 +16541 Napsa MGI:MGI:109365|Ensembl:ENSMUSG00000002204|Vega:OTTMUSG00000021117 +16542 Kdr MGI:MGI:96683|Ensembl:ENSMUSG00000062960|Vega:OTTMUSG00000021297 +16543 Mdfic MGI:MGI:104611|Ensembl:ENSMUSG00000041390|Vega:OTTMUSG00000021421 +16545 Kera MGI:MGI:1202398|Ensembl:ENSMUSG00000019932 +16548 Khk MGI:MGI:1096353|Ensembl:ENSMUSG00000029162|Vega:OTTMUSG00000030395 +16549 Khsrp MGI:MGI:1336214|Ensembl:ENSMUSG00000007670 +16551 Kif11 MGI:MGI:1098231|Ensembl:ENSMUSG00000012443 +16552 Kif12 MGI:MGI:1098232|Ensembl:ENSMUSG00000028357|Vega:OTTMUSG00000000243 +16553 Kif13a MGI:MGI:1098264|Ensembl:ENSMUSG00000021375 +16554 Kif13b MGI:MGI:1098265|Ensembl:ENSMUSG00000060012 +16558 Kif16b MGI:MGI:1098240|Ensembl:ENSMUSG00000038844|Vega:OTTMUSG00000015608 +16559 Kif17 MGI:MGI:1098229|Ensembl:ENSMUSG00000028758|Vega:OTTMUSG00000009977 +16560 Kif1a MGI:MGI:108391|Ensembl:ENSMUSG00000014602|Vega:OTTMUSG00000048636 +16561 Kif1b MGI:MGI:108426|Ensembl:ENSMUSG00000063077|Vega:OTTMUSG00000010170 +16562 Kif1c MGI:MGI:1098260|Ensembl:ENSMUSG00000020821|Vega:OTTMUSG00000006075 +16563 Kif2a MGI:MGI:108390|Ensembl:ENSMUSG00000021693|Vega:OTTMUSG00000029368 +16564 Kif21a MGI:MGI:109188|Ensembl:ENSMUSG00000022629 +16565 Kif21b MGI:MGI:109234|Ensembl:ENSMUSG00000041642|Vega:OTTMUSG00000026867 +16568 Kif3a MGI:MGI:107689|Ensembl:ENSMUSG00000018395|Vega:OTTMUSG00000005634 +16569 Kif3b MGI:MGI:107688|Ensembl:ENSMUSG00000027475|Vega:OTTMUSG00000016751 +16570 Kif3c MGI:MGI:107979|Ensembl:ENSMUSG00000020668 +16571 Kif4 MGI:MGI:108389|Ensembl:ENSMUSG00000034311|Vega:OTTMUSG00000018285 +16572 Kif5a MGI:MGI:109564|Ensembl:ENSMUSG00000074657 +16573 Kif5b MGI:MGI:1098268|Ensembl:ENSMUSG00000006740|Vega:OTTMUSG00000035843 +16574 Kif5c MGI:MGI:1098269|Ensembl:ENSMUSG00000026764|Vega:OTTMUSG00000012481 +16576 Kif7 MGI:MGI:1098239|Ensembl:ENSMUSG00000050382|Vega:OTTMUSG00000044965 +16577 Kif8 MGI:MGI:1098210 +16578 Kif9 MGI:MGI:1098237|Ensembl:ENSMUSG00000032489|Vega:OTTMUSG00000021051 +16579 Kifap3 MGI:MGI:107566|Ensembl:ENSMUSG00000026585|Vega:OTTMUSG00000018234 +16580 Kifc5b MGI:MGI:2137414|Ensembl:ENSMUSG00000024301 +16581 Kifc2 MGI:MGI:109187|Ensembl:ENSMUSG00000004187 +16582 Kifc3 MGI:MGI:109202|Ensembl:ENSMUSG00000031788|Vega:OTTMUSG00000061734 +16588 Kin MGI:MGI:96676|Ensembl:ENSMUSG00000037262|Vega:OTTMUSG00000011190 +16589 Uhmk1 MGI:MGI:1341908|Ensembl:ENSMUSG00000026667|Vega:OTTMUSG00000021543 +16590 Kit MGI:MGI:96677|Ensembl:ENSMUSG00000005672|Vega:OTTMUSG00000016671 +16591 Kl MGI:MGI:1101771|Ensembl:ENSMUSG00000058488|Vega:OTTMUSG00000055554 +16592 Fabp5 MGI:MGI:101790|Ensembl:ENSMUSG00000027533|Vega:OTTMUSG00000029875 +16593 Klc1 MGI:MGI:107978|Ensembl:ENSMUSG00000021288|Vega:OTTMUSG00000027507 +16594 Klc2 MGI:MGI:107953|Ensembl:ENSMUSG00000024862|Vega:OTTMUSG00000016355 +16596 Klf1 MGI:MGI:1342771|Ensembl:ENSMUSG00000054191|Vega:OTTMUSG00000061396 +16597 Klf12 MGI:MGI:1333796|Ensembl:ENSMUSG00000072294 +16598 Klf2 MGI:MGI:1342772|Ensembl:ENSMUSG00000055148|Vega:OTTMUSG00000022542 +16599 Klf3 MGI:MGI:1342773|Ensembl:ENSMUSG00000029178|Vega:OTTMUSG00000055125 +16600 Klf4 MGI:MGI:1342287|Ensembl:ENSMUSG00000003032|Vega:OTTMUSG00000007231 +16601 Klf9 MGI:MGI:1333856|Ensembl:ENSMUSG00000033863 +16602 Klk1b2-ps MGI:MGI:892029 +16603 Klk2-ps MGI:MGI:892028 +16604 Klk1b7-ps MGI:MGI:892027|Ensembl:ENSMUSG00000060161 +16605 Klk1b10-ps MGI:MGI:892026 +16607 Klk1b15-ps MGI:MGI:891987 +16609 Klk1b18-ps MGI:MGI:892024 +16612 Klk1 MGI:MGI:102850|Ensembl:ENSMUSG00000063903|Vega:OTTMUSG00000058322 +16613 Klk1b11 MGI:MGI:892023|Ensembl:ENSMUSG00000044485|Vega:OTTMUSG00000027240 +16614 Klk1b14-ps MGI:MGI:891983 +16615 Klk1b16 MGI:MGI:891982|Ensembl:ENSMUSG00000038968|Vega:OTTMUSG00000027255 +16616 Klk1b21 MGI:MGI:892022|Ensembl:ENSMUSG00000066516|Vega:OTTMUSG00000058319 +16617 Klk1b24 MGI:MGI:892021|Ensembl:ENSMUSG00000063713|Vega:OTTMUSG00000027256 +16618 Klk1b26 MGI:MGI:891981|Ensembl:ENSMUSG00000053719|Vega:OTTMUSG00000058702 +16619 Klk1b27 MGI:MGI:891980|Ensembl:ENSMUSG00000063177|Vega:OTTMUSG00000027241 +16621 Klkb1 MGI:MGI:102849|Ensembl:ENSMUSG00000109764|Vega:OTTMUSG00000033163 +16622 Klk1b5 MGI:MGI:892020|Ensembl:ENSMUSG00000066512|Vega:OTTMUSG00000027272 +16623 Klk1b1 MGI:MGI:892019|Ensembl:ENSMUSG00000063133|Vega:OTTMUSG00000058317 +16624 Klk1b8 MGI:MGI:892018|Ensembl:ENSMUSG00000063089|Vega:OTTMUSG00000027232 +16625 Serpina3c MGI:MGI:102848|Ensembl:ENSMUSG00000066361|Vega:OTTMUSG00000027583 +16627 Klra1 MGI:MGI:101907|Ensembl:ENSMUSG00000079853|Vega:OTTMUSG00000022866 +16628 Klra10 MGI:MGI:1321093|Ensembl:ENSMUSG00000072718|Vega:OTTMUSG00000022863 +16630 Klra12 MGI:MGI:1321091 +16631 Klra13-ps MGI:MGI:1321090|Ensembl:ENSMUSG00000030178 +16633 Klra2 MGI:MGI:101906|Ensembl:ENSMUSG00000030187|Vega:OTTMUSG00000027143 +16634 Klra3 MGI:MGI:101905|Ensembl:ENSMUSG00000067591|Vega:OTTMUSG00000022864 +16635 Klra4 MGI:MGI:101904|Ensembl:ENSMUSG00000079852|Vega:OTTMUSG00000026915 +16636 Klra5 MGI:MGI:101903|Ensembl:ENSMUSG00000030173|Vega:OTTMUSG00000026913 +16637 Klra6 MGI:MGI:101902|Ensembl:ENSMUSG00000061769|Vega:OTTMUSG00000026911 +16638 Klra7 MGI:MGI:101901|Ensembl:ENSMUSG00000067599|Vega:OTTMUSG00000022875 +16639 Klra8 MGI:MGI:102968|Ensembl:ENSMUSG00000089727|Vega:OTTMUSG00000026958 +16640 Klra9 MGI:MGI:1321153|Ensembl:ENSMUSG00000033024|Vega:OTTMUSG00000023020 +16641 Klrc1 MGI:MGI:1336161|Ensembl:ENSMUSG00000030167|Vega:OTTMUSG00000032510 +16642 Klrc2 MGI:MGI:1336162|Ensembl:ENSMUSG00000052736|Vega:OTTMUSG00000032508 +16643 Klrd1 MGI:MGI:1196275|Ensembl:ENSMUSG00000030165|Vega:OTTMUSG00000032506 +16644 Kng1 MGI:MGI:1097705|Ensembl:ENSMUSG00000022875|Vega:OTTMUSG00000025899 +16646 Kpna1 MGI:MGI:103560|Ensembl:ENSMUSG00000022905|Vega:OTTMUSG00000038076 +16647 Kpna2 MGI:MGI:103561|Ensembl:ENSMUSG00000018362|Vega:OTTMUSG00000003580 +16648 Kpna3 MGI:MGI:1100863|Ensembl:ENSMUSG00000021929 +16649 Kpna4 MGI:MGI:1100848|Ensembl:ENSMUSG00000027782|Vega:OTTMUSG00000029117 +16650 Kpna6 MGI:MGI:1100836|Ensembl:ENSMUSG00000003731|Vega:OTTMUSG00000009518 +16651 Sspn MGI:MGI:1353511|Ensembl:ENSMUSG00000030255|Vega:OTTMUSG00000025460 +16653 Kras MGI:MGI:96680|Ensembl:ENSMUSG00000030265|Vega:OTTMUSG00000022179 +16656 Hivep3 MGI:MGI:106589|Ensembl:ENSMUSG00000028634|Vega:OTTMUSG00000008783 +16658 Mafb MGI:MGI:104555|Ensembl:ENSMUSG00000074622|Vega:OTTMUSG00000001175 +16659 Krt31c MGI:MGI:96684 +16660 Krt31 MGI:MGI:1309993|Ensembl:ENSMUSG00000048981|Vega:OTTMUSG00000002219 +16661 Krt10 MGI:MGI:96685|Ensembl:ENSMUSG00000019761|Vega:OTTMUSG00000004962 +16663 Krt13 MGI:MGI:101925|Ensembl:ENSMUSG00000044041|Vega:OTTMUSG00000002539 +16664 Krt14 MGI:MGI:96688|Ensembl:ENSMUSG00000045545|Vega:OTTMUSG00000002538 +16665 Krt15 MGI:MGI:96689|Ensembl:ENSMUSG00000054146|Vega:OTTMUSG00000002551 +16666 Krt16 MGI:MGI:96690|Ensembl:ENSMUSG00000053797|Vega:OTTMUSG00000002540 +16667 Krt17 MGI:MGI:96691|Ensembl:ENSMUSG00000035557|Vega:OTTMUSG00000002546 +16668 Krt18 MGI:MGI:96692|Ensembl:ENSMUSG00000023043 +16669 Krt19 MGI:MGI:96693|Ensembl:ENSMUSG00000020911|Vega:OTTMUSG00000002545 +16670 Krt32 MGI:MGI:1309995|Ensembl:ENSMUSG00000046095|Vega:OTTMUSG00000002216 +16671 Krt33b MGI:MGI:1309991|Ensembl:ENSMUSG00000057723|Vega:OTTMUSG00000002195 +16672 Krt34 MGI:MGI:1309994|Ensembl:ENSMUSG00000043485|Vega:OTTMUSG00000002178 +16673 Krt36 MGI:MGI:109364|Ensembl:ENSMUSG00000020916|Vega:OTTMUSG00000002549 +16675 Krt27 MGI:MGI:1339999|Ensembl:ENSMUSG00000017588|Vega:OTTMUSG00000006439 +16678 Krt1 MGI:MGI:96698|Ensembl:ENSMUSG00000046834 +16679 Krt86 MGI:MGI:109362|Ensembl:ENSMUSG00000067614 +16680 Krt84 MGI:MGI:96700|Ensembl:ENSMUSG00000044294 +16681 Krt2 MGI:MGI:96699|Ensembl:ENSMUSG00000064201|Vega:OTTMUSG00000033498 +16682 Krt4 MGI:MGI:96701|Ensembl:ENSMUSG00000059668 +16687 Krt6a MGI:MGI:1100845|Ensembl:ENSMUSG00000058354 +16688 Krt6b MGI:MGI:1333768|Ensembl:ENSMUSG00000023041 +16691 Krt8 MGI:MGI:96705|Ensembl:ENSMUSG00000049382 +16693 Krtap11-1 MGI:MGI:99447|Ensembl:ENSMUSG00000091212|Vega:OTTMUSG00000044988 +16694 Krtap12-1 MGI:MGI:1328315|Ensembl:ENSMUSG00000069583 +16697 Gm10272 MGI:MGI:3642183|Ensembl:ENSMUSG00000069584 +16699 Krtap13 MGI:MGI:1330835|Ensembl:ENSMUSG00000050224 +16700 Krtap6-1 MGI:MGI:1330228|Ensembl:ENSMUSG00000058172 +16701 Krtap6-2 MGI:MGI:1330280|Ensembl:ENSMUSG00000062433|Vega:OTTMUSG00000045005 +16703 Krtap8-1 MGI:MGI:1330293|Ensembl:ENSMUSG00000059632 +16704 Krtap19-5 MGI:MGI:1330295|Ensembl:ENSMUSG00000051802 +16705 Krtap9-1 MGI:MGI:1309997|Ensembl:ENSMUSG00000070335|Vega:OTTMUSG00000002184 +16706 Ksr1 MGI:MGI:105051|Ensembl:ENSMUSG00000018334|Vega:OTTMUSG00000000155 +16709 Ktn1 MGI:MGI:109153|Ensembl:ENSMUSG00000021843|Vega:OTTMUSG00000045014 +16716 Ky MGI:MGI:96709|Ensembl:ENSMUSG00000035606|Vega:OTTMUSG00000048441 +16717 l17Pas2 MGI:MGI:96710 +16719 l17Wis10 MGI:MGI:96712 +16720 l17Wis11 MGI:MGI:96713 +16721 l17Wis3 MGI:MGI:96714 +16722 l17Wis4 MGI:MGI:96715 +16723 l17Wis5 MGI:MGI:96716 +16724 l17Wis6 MGI:MGI:96717 +16725 l17Wis7 MGI:MGI:96718 +16726 l17Wis8 MGI:MGI:96719 +16727 l17Wis9 MGI:MGI:96720 +16728 L1cam MGI:MGI:96721|Ensembl:ENSMUSG00000031391|Vega:OTTMUSG00000016517 +16730 L1Md-Tf14 MGI:MGI:1332649 +16731 L1Md-Tf17 MGI:MGI:1332647 +16732 L1Md-Tf18 MGI:MGI:1332653 +16733 L1Md-Tf23 MGI:MGI:1332646 +16734 L1Md-Tf26 MGI:MGI:1332667 +16735 L1Md-Tf29 MGI:MGI:1332651 +16736 L1Md-Tf30 MGI:MGI:1332645 +16737 L1Md-Tf5 MGI:MGI:1332641 +16738 L1Md-Tf6 MGI:MGI:1332640 +16739 L1Md-Tf8 MGI:MGI:1332644 +16740 L1Md-Tf9 MGI:MGI:1332643 +16743 l1Rk1 MGI:MGI:96724 +16744 l1Rk2 MGI:MGI:96725 +16745 l1Rk4 MGI:MGI:96726 +16746 l1Rk5 MGI:MGI:96727 +16747 l1Rk6 MGI:MGI:96728 +16748 l1Rk7 MGI:MGI:96729 +16749 l1Rk8 MGI:MGI:96730 +16750 l4Rn1 MGI:MGI:99786 +16751 l4Rn2 MGI:MGI:99785 +16752 l4Rn3 MGI:MGI:99784 +16753 l5H1 MGI:MGI:96731 +16754 l7Rk1 MGI:MGI:96732 +16755 l7Rn1 MGI:MGI:96733 +16756 l7Rn2 MGI:MGI:96734 +16758 l7Rn4 MGI:MGI:96736 +16761 Labx MGI:MGI:1098245 +16763 Lad1 MGI:MGI:109343|Ensembl:ENSMUSG00000041782|Vega:OTTMUSG00000049829 +16764 Aff3 MGI:MGI:106927|Ensembl:ENSMUSG00000037138|Vega:OTTMUSG00000019698 +16765 Stmn1 MGI:MGI:96739|Ensembl:ENSMUSG00000028832|Vega:OTTMUSG00000010830 +16768 Lag3 MGI:MGI:106588|Ensembl:ENSMUSG00000030124|Vega:OTTMUSG00000024400 +16769 Dsg4 MGI:MGI:2661061|Ensembl:ENSMUSG00000001804|Vega:OTTMUSG00000028141 +16770 Lalba MGI:MGI:96742|Ensembl:ENSMUSG00000022991 +16772 Lama1 MGI:MGI:99892|Ensembl:ENSMUSG00000032796 +16773 Lama2 MGI:MGI:99912|Ensembl:ENSMUSG00000019899|Vega:OTTMUSG00000045038 +16774 Lama3 MGI:MGI:99909|Ensembl:ENSMUSG00000024421|Vega:OTTMUSG00000045059 +16775 Lama4 MGI:MGI:109321|Ensembl:ENSMUSG00000019846|Vega:OTTMUSG00000034993 +16776 Lama5 MGI:MGI:105382|Ensembl:ENSMUSG00000015647|Vega:OTTMUSG00000016271 +16777 Lamb1 MGI:MGI:96743|Ensembl:ENSMUSG00000002900|Vega:OTTMUSG00000035464 +16779 Lamb2 MGI:MGI:99916|Ensembl:ENSMUSG00000052911|Vega:OTTMUSG00000050824 +16780 Lamb3 MGI:MGI:99915|Ensembl:ENSMUSG00000026639|Vega:OTTMUSG00000025453 +16782 Lamc2 MGI:MGI:99913|Ensembl:ENSMUSG00000026479|Vega:OTTMUSG00000049711 +16783 Lamp1 MGI:MGI:96745|Ensembl:ENSMUSG00000031447|Vega:OTTMUSG00000060871 +16784 Lamp2 MGI:MGI:96748|Ensembl:ENSMUSG00000016534|Vega:OTTMUSG00000017230 +16785 Rpsa MGI:MGI:105381|Ensembl:ENSMUSG00000032518|Vega:OTTMUSG00000062571 +16790 Anpep MGI:MGI:5000466|Ensembl:ENSMUSG00000039062|Vega:OTTMUSG00000022543 +16792 Laptm5 MGI:MGI:108046|Ensembl:ENSMUSG00000028581|Vega:OTTMUSG00000009589 +16795 Large1 MGI:MGI:1342270|Ensembl:ENSMUSG00000004383|Vega:OTTMUSG00000030306 +16796 Lasp1 MGI:MGI:109656|Ensembl:ENSMUSG00000038366|Vega:OTTMUSG00000002777 +16797 Lat MGI:MGI:1342293|Ensembl:ENSMUSG00000030742|Vega:OTTMUSG00000058212 +16798 Lats1 MGI:MGI:1333883|Ensembl:ENSMUSG00000040021 +16800 Arhgef2 MGI:MGI:103264|Ensembl:ENSMUSG00000028059|Vega:OTTMUSG00000042225 +16801 Arhgef1 MGI:MGI:1353510|Ensembl:ENSMUSG00000040940|Vega:OTTMUSG00000029276 +16803 Lbp MGI:MGI:1098776|Ensembl:ENSMUSG00000016024|Vega:OTTMUSG00000015936 +16814 Lbx1 MGI:MGI:104867|Ensembl:ENSMUSG00000025216|Vega:OTTMUSG00000037523 +16815 Lbx2 MGI:MGI:1342288|Ensembl:ENSMUSG00000034968|Vega:OTTMUSG00000023349 +16816 Lcat MGI:MGI:96755|Ensembl:ENSMUSG00000035237|Vega:OTTMUSG00000031021 +16818 Lck MGI:MGI:96756|Ensembl:ENSMUSG00000000409|Vega:OTTMUSG00000009667 +16819 Lcn2 MGI:MGI:96757|Ensembl:ENSMUSG00000026822|Vega:OTTMUSG00000012958 +16820 Lcn3 MGI:MGI:102669|Ensembl:ENSMUSG00000026936|Vega:OTTMUSG00000012627 +16821 Lcn4 MGI:MGI:102668|Ensembl:ENSMUSG00000026919|Vega:OTTMUSG00000011582 +16822 Lcp2 MGI:MGI:1321402|Ensembl:ENSMUSG00000002699|Vega:OTTMUSG00000005404 +16825 Ldb1 MGI:MGI:894762|Ensembl:ENSMUSG00000025223|Vega:OTTMUSG00000033442 +16826 Ldb2 MGI:MGI:894670|Ensembl:ENSMUSG00000039706|Vega:OTTMUSG00000053817 +16828 Ldha MGI:MGI:96759|Ensembl:ENSMUSG00000063229|Vega:OTTMUSG00000016500 +16829 Ldha-ps MGI:MGI:96760 +16830 Ldha-ps2 MGI:MGI:96761 +16832 Ldhb MGI:MGI:96763|Ensembl:ENSMUSG00000030246|Vega:OTTMUSG00000016379 +16833 Ldhc MGI:MGI:96764|Ensembl:ENSMUSG00000030851|Vega:OTTMUSG00000027259 +16834 Cog1 MGI:MGI:1333873|Ensembl:ENSMUSG00000018661|Vega:OTTMUSG00000003397 +16835 Ldlr MGI:MGI:96765|Ensembl:ENSMUSG00000032193|Vega:OTTMUSG00000063513 +16839 lec MGI:MGI:96769 +16840 Cnmd MGI:MGI:1341171|Ensembl:ENSMUSG00000022025|Vega:OTTMUSG00000035201 +16841 Lect2 MGI:MGI:1278342|Ensembl:ENSMUSG00000021539 +16842 Lef1 MGI:MGI:96770|Ensembl:ENSMUSG00000027985|Vega:OTTMUSG00000020276 +16846 Lep MGI:MGI:104663|Ensembl:ENSMUSG00000059201|Vega:OTTMUSG00000035815 +16847 Lepr MGI:MGI:104993|Ensembl:ENSMUSG00000057722|Vega:OTTMUSG00000008454 +16848 Lfng MGI:MGI:1095413|Ensembl:ENSMUSG00000029570|Vega:OTTMUSG00000054831 +16851 lg MGI:MGI:96775 +16852 Lgals1 MGI:MGI:96777|Ensembl:ENSMUSG00000068220 +16854 Lgals3 MGI:MGI:96778|Ensembl:ENSMUSG00000050335|Vega:OTTMUSG00000032779 +16855 Lgals4 MGI:MGI:107536|Ensembl:ENSMUSG00000053964|Vega:OTTMUSG00000022686 +16857 Lgals6 MGI:MGI:107535 +16858 Lgals7 MGI:MGI:1316742|Ensembl:ENSMUSG00000053522|Vega:OTTMUSG00000022690 +16859 Lgals9 MGI:MGI:109496|Ensembl:ENSMUSG00000001123|Vega:OTTMUSG00000000163 +16860 lgh MGI:MGI:96779 +16862 lgl MGI:MGI:96780 +16864 lgr MGI:MGI:96781 +16865 Eif2d MGI:MGI:109342|Ensembl:ENSMUSG00000026427|Vega:OTTMUSG00000021553 +16866 Lhb MGI:MGI:96782|Ensembl:ENSMUSG00000100916|Vega:OTTMUSG00000023868 +16867 Lhcgr MGI:MGI:96783|Ensembl:ENSMUSG00000024107 +16869 Lhx1 MGI:MGI:99783|Ensembl:ENSMUSG00000018698|Vega:OTTMUSG00000000972 +16870 Lhx2 MGI:MGI:96785|Ensembl:ENSMUSG00000000247|Vega:OTTMUSG00000012866 +16871 Lhx3 MGI:MGI:102673|Ensembl:ENSMUSG00000026934|Vega:OTTMUSG00000012728 +16872 Lhx4 MGI:MGI:101776|Ensembl:ENSMUSG00000026468|Vega:OTTMUSG00000039744 +16873 Lhx5 MGI:MGI:107792|Ensembl:ENSMUSG00000029595|Vega:OTTMUSG00000039746 +16874 Lhx6 MGI:MGI:1306803|Ensembl:ENSMUSG00000026890|Vega:OTTMUSG00000012098 +16875 Lhx8 MGI:MGI:1096343|Ensembl:ENSMUSG00000096225|Vega:OTTMUSG00000039751 +16876 Lhx9 MGI:MGI:1316721|Ensembl:ENSMUSG00000019230|Vega:OTTMUSG00000022572 +16878 Lif MGI:MGI:96787|Ensembl:ENSMUSG00000034394|Vega:OTTMUSG00000005061 +16880 Lifr MGI:MGI:96788|Ensembl:ENSMUSG00000054263 +16881 Lig1 MGI:MGI:101789|Ensembl:ENSMUSG00000056394 +16882 Lig3 MGI:MGI:109152|Ensembl:ENSMUSG00000020697|Vega:OTTMUSG00000000931 +16885 Limk1 MGI:MGI:104572|Ensembl:ENSMUSG00000029674|Vega:OTTMUSG00000026202 +16886 Limk2 MGI:MGI:1197517|Ensembl:ENSMUSG00000020451|Vega:OTTMUSG00000000764 +16889 Lipa MGI:MGI:96789|Ensembl:ENSMUSG00000024781 +16890 Lipe MGI:MGI:96790|Ensembl:ENSMUSG00000003123|Vega:OTTMUSG00000034139 +16891 Lipg MGI:MGI:1341803|Ensembl:ENSMUSG00000053846 +16895 ll MGI:MGI:96791 +16896 lla MGI:MGI:1096375 +16897 Llgl1 MGI:MGI:102682|Ensembl:ENSMUSG00000020536|Vega:OTTMUSG00000007769 +16898 Rps2 MGI:MGI:105110|Ensembl:ENSMUSG00000044533|Vega:OTTMUSG00000029228 +16904 Gzmm MGI:MGI:99549|Ensembl:ENSMUSG00000054206|Vega:OTTMUSG00000027871 +16905 Lmna MGI:MGI:96794|Ensembl:ENSMUSG00000028063|Vega:OTTMUSG00000030317 +16906 Lmnb1 MGI:MGI:96795|Ensembl:ENSMUSG00000024590|Vega:OTTMUSG00000016318 +16907 Lmnb2 MGI:MGI:96796|Ensembl:ENSMUSG00000062075|Vega:OTTMUSG00000031736 +16909 Lmo2 MGI:MGI:102811|Ensembl:ENSMUSG00000032698|Vega:OTTMUSG00000014900 +16911 Lmo4 MGI:MGI:109360|Ensembl:ENSMUSG00000028266|Vega:OTTMUSG00000029080 +16912 Psmb9 MGI:MGI:1346526|Ensembl:ENSMUSG00000096727|Vega:OTTMUSG00000036472 +16913 Psmb8 MGI:MGI:1346527|Ensembl:ENSMUSG00000024338|Vega:OTTMUSG00000037118 +16917 Lmx1b MGI:MGI:1100513|Ensembl:ENSMUSG00000038765|Vega:OTTMUSG00000012589 +16918 Mycl MGI:MGI:96799|Ensembl:ENSMUSG00000028654|Vega:OTTMUSG00000008931 +16922 Phyh MGI:MGI:891978|Ensembl:ENSMUSG00000026664|Vega:OTTMUSG00000010818 +16923 Sh2b3 MGI:MGI:893598|Ensembl:ENSMUSG00000042594|Vega:OTTMUSG00000029807 +16924 Lnx1 MGI:MGI:1278335|Ensembl:ENSMUSG00000029228|Vega:OTTMUSG00000028588 +16931 lop2 MGI:MGI:96808 +16939 Lor MGI:MGI:96816|Ensembl:ENSMUSG00000043165|Vega:OTTMUSG00000045087 +16948 Lox MGI:MGI:96817|Ensembl:ENSMUSG00000024529 +16949 Loxl1 MGI:MGI:106096|Ensembl:ENSMUSG00000032334|Vega:OTTMUSG00000063237 +16950 Loxl3 MGI:MGI:1337004|Ensembl:ENSMUSG00000000693|Vega:OTTMUSG00000022487 +16952 Anxa1 MGI:MGI:96819|Ensembl:ENSMUSG00000024659|Vega:OTTMUSG00000035986 +16956 Lpl MGI:MGI:96820|Ensembl:ENSMUSG00000015568|Vega:OTTMUSG00000036084 +16963 Xcl1 MGI:MGI:104593|Ensembl:ENSMUSG00000026573|Vega:OTTMUSG00000026875 +16969 Zbtb7a MGI:MGI:1335091|Ensembl:ENSMUSG00000035011|Vega:OTTMUSG00000030304 +16970 Lrmp MGI:MGI:108424|Ensembl:ENSMUSG00000030263|Vega:OTTMUSG00000024094 +16971 Lrp1 MGI:MGI:96828|Ensembl:ENSMUSG00000040249|Vega:OTTMUSG00000031813 +16973 Lrp5 MGI:MGI:1278315|Ensembl:ENSMUSG00000024913|Vega:OTTMUSG00000042195 +16974 Lrp6 MGI:MGI:1298218|Ensembl:ENSMUSG00000030201|Vega:OTTMUSG00000021240 +16975 Lrp8 MGI:MGI:1340044|Ensembl:ENSMUSG00000028613|Vega:OTTMUSG00000009153 +16976 Lrpap1 MGI:MGI:96829|Ensembl:ENSMUSG00000029103|Vega:OTTMUSG00000023232 +16977 Lrrc23 MGI:MGI:1315192|Ensembl:ENSMUSG00000030125|Vega:OTTMUSG00000023600 +16978 Lrrfip1 MGI:MGI:1342770|Ensembl:ENSMUSG00000026305|Vega:OTTMUSG00000048410 +16979 Lrrn1 MGI:MGI:106038|Ensembl:ENSMUSG00000034648|Vega:OTTMUSG00000056425 +16980 Lrrn2 MGI:MGI:106037|Ensembl:ENSMUSG00000026443|Vega:OTTMUSG00000029281 +16981 Lrrn3 MGI:MGI:106036|Ensembl:ENSMUSG00000036295 +16985 Lsp1 MGI:MGI:96832|Ensembl:ENSMUSG00000018819|Vega:OTTMUSG00000018784 +16987 Lss MGI:MGI:1336155|Ensembl:ENSMUSG00000033105|Vega:OTTMUSG00000027872 +16988 Lst1 MGI:MGI:1096324|Ensembl:ENSMUSG00000073412|Vega:OTTMUSG00000033230 +16990 lt MGI:MGI:96835 +16991 Lt1 MGI:MGI:1100855 +16992 Lta MGI:MGI:104797|Ensembl:ENSMUSG00000024402|Vega:OTTMUSG00000037197 +16993 Lta4h MGI:MGI:96836|Ensembl:ENSMUSG00000015889|Vega:OTTMUSG00000063908 +16994 Ltb MGI:MGI:104796|Ensembl:ENSMUSG00000024399|Vega:OTTMUSG00000037195 +16995 Ltb4r1 MGI:MGI:1309472|Ensembl:ENSMUSG00000046908|Vega:OTTMUSG00000034668 +16997 Ltbp2 MGI:MGI:99502|Ensembl:ENSMUSG00000002020|Vega:OTTMUSG00000036546 +16998 Ltbp3 MGI:MGI:1101355|Ensembl:ENSMUSG00000024940 +17000 Ltbr MGI:MGI:104875|Ensembl:ENSMUSG00000030339|Vega:OTTMUSG00000034580 +17001 Ltc4s MGI:MGI:107498|Ensembl:ENSMUSG00000020377|Vega:OTTMUSG00000005578 +17002 Ltf MGI:MGI:96837|Ensembl:ENSMUSG00000032496|Vega:OTTMUSG00000052503 +17005 Ltk MGI:MGI:96840|Ensembl:ENSMUSG00000027297|Vega:OTTMUSG00000016528 +17007 ltnr1 MGI:MGI:108000 +17008 ltnr2 MGI:MGI:107989 +17022 Lum MGI:MGI:109347|Ensembl:ENSMUSG00000036446 +17025 Alad MGI:MGI:96853|Ensembl:ENSMUSG00000028393|Vega:OTTMUSG00000009022 +17034 Lx MGI:MGI:96856 +17035 Lxn MGI:MGI:107633|Ensembl:ENSMUSG00000047557|Vega:OTTMUSG00000029073 +17055 Klra MGI:MGI:96876 +17057 Klrb1a MGI:MGI:107540|Ensembl:ENSMUSG00000030361|Vega:OTTMUSG00000029164 +17059 Klrb1c MGI:MGI:107538|Ensembl:ENSMUSG00000030325|Vega:OTTMUSG00000037663 +17060 Blnk MGI:MGI:96878|Ensembl:ENSMUSG00000061132|Vega:OTTMUSG00000031860 +17062 Ly6 MGI:MGI:96880 +17063 Muc13 MGI:MGI:103190|Ensembl:ENSMUSG00000022824|Vega:OTTMUSG00000024944 +17064 Cd93 MGI:MGI:106664|Ensembl:ENSMUSG00000027435|Vega:OTTMUSG00000015713 +17067 Ly6c1 MGI:MGI:96882|Ensembl:ENSMUSG00000079018|Vega:OTTMUSG00000045162 +17068 Ly6d MGI:MGI:96881|Ensembl:ENSMUSG00000034634|Vega:OTTMUSG00000045140 +17069 Ly6e MGI:MGI:106651|Ensembl:ENSMUSG00000022587|Vega:OTTMUSG00000045205 +17071 Ly6f MGI:MGI:109441|Ensembl:ENSMUSG00000022583|Vega:OTTMUSG00000045190 +17075 Epcam MGI:MGI:106653|Ensembl:ENSMUSG00000045394 +17076 Ly75 MGI:MGI:106662|Ensembl:ENSMUSG00000026980|Vega:OTTMUSG00000012816 +17079 Cd180 MGI:MGI:1194924|Ensembl:ENSMUSG00000021624|Vega:OTTMUSG00000035367 +17082 Il1rl1 MGI:MGI:98427|Ensembl:ENSMUSG00000026069|Vega:OTTMUSG00000037806 +17083 Tmed1 MGI:MGI:106201|Ensembl:ENSMUSG00000032180|Vega:OTTMUSG00000063454 +17084 Ly86 MGI:MGI:1321404|Ensembl:ENSMUSG00000021423 +17085 Ly9 MGI:MGI:96885|Ensembl:ENSMUSG00000004707|Vega:OTTMUSG00000016916 +17086 Ncr1 MGI:MGI:1336212|Ensembl:ENSMUSG00000062524|Vega:OTTMUSG00000027904 +17087 Ly96 MGI:MGI:1341909|Ensembl:ENSMUSG00000025779|Vega:OTTMUSG00000048080 +17089 Lyar MGI:MGI:107470|Ensembl:ENSMUSG00000067367|Vega:OTTMUSG00000023311 +17095 Lyl1 MGI:MGI:96891|Ensembl:ENSMUSG00000034041 +17096 Lyn MGI:MGI:96892|Ensembl:ENSMUSG00000042228|Vega:OTTMUSG00000004398 +17101 Lyst MGI:MGI:107448|Ensembl:ENSMUSG00000019726 +17105 Lyz2 MGI:MGI:96897|Ensembl:ENSMUSG00000069516 +17106 lz MGI:MGI:96898 +17110 Lyz1 MGI:MGI:96902|Ensembl:ENSMUSG00000069515 +17112 Tm4sf1 MGI:MGI:104678|Ensembl:ENSMUSG00000027800|Vega:OTTMUSG00000052837 +17113 M6pr MGI:MGI:96904|Ensembl:ENSMUSG00000007458|Vega:OTTMUSG00000023879 +17114 M6pr-ps MGI:MGI:96905 +17116 Mab21l1 MGI:MGI:1333773|Ensembl:ENSMUSG00000056947|Vega:OTTMUSG00000053042 +17117 Amacr MGI:MGI:1098273|Ensembl:ENSMUSG00000022244 +17118 Marcks MGI:MGI:96907|Ensembl:ENSMUSG00000069662|Vega:OTTMUSG00000042361 +17119 Mxd1 MGI:MGI:96908|Ensembl:ENSMUSG00000001156|Vega:OTTMUSG00000056544 +17120 Mad1l1 MGI:MGI:1341857|Ensembl:ENSMUSG00000029554|Vega:OTTMUSG00000030671 +17121 Mxd3 MGI:MGI:104987|Ensembl:ENSMUSG00000021485|Vega:OTTMUSG00000020954 +17122 Mxd4 MGI:MGI:104991|Ensembl:ENSMUSG00000037235|Vega:OTTMUSG00000026714 +17123 Madcam1 MGI:MGI:103579|Ensembl:ENSMUSG00000020310 +17125 Smad1 MGI:MGI:109452|Ensembl:ENSMUSG00000031681|Vega:OTTMUSG00000021109 +17126 Smad2 MGI:MGI:108051|Ensembl:ENSMUSG00000024563|Vega:OTTMUSG00000036536 +17127 Smad3 MGI:MGI:1201674|Ensembl:ENSMUSG00000032402|Vega:OTTMUSG00000021500 +17128 Smad4 MGI:MGI:894293|Ensembl:ENSMUSG00000024515|Vega:OTTMUSG00000021090 +17129 Smad5 MGI:MGI:1328787|Ensembl:ENSMUSG00000021540|Vega:OTTMUSG00000020956 +17130 Smad6 MGI:MGI:1336883|Ensembl:ENSMUSG00000036867|Vega:OTTMUSG00000021505 +17131 Smad7 MGI:MGI:1100518|Ensembl:ENSMUSG00000025880|Vega:OTTMUSG00000024306 +17132 Maf MGI:MGI:96909|Ensembl:ENSMUSG00000055435|Vega:OTTMUSG00000024922 +17133 Maff MGI:MGI:96910|Ensembl:ENSMUSG00000042622 +17134 Mafg MGI:MGI:96911|Ensembl:ENSMUSG00000051510|Vega:OTTMUSG00000004094 +17135 Mafk MGI:MGI:99951|Ensembl:ENSMUSG00000018143|Vega:OTTMUSG00000025256 +17136 Mag MGI:MGI:96912|Ensembl:ENSMUSG00000036634|Vega:OTTMUSG00000049785 +17137 Magea1 MGI:MGI:1333834|Ensembl:ENSMUSG00000096644|Vega:OTTMUSG00000019349 +17138 Magea2 MGI:MGI:1333793|Ensembl:ENSMUSG00000055746|Vega:OTTMUSG00000019355 +17139 Magea3 MGI:MGI:1333832|Ensembl:ENSMUSG00000094196|Vega:OTTMUSG00000019258 +17140 Magea4 MGI:MGI:1333839|Ensembl:ENSMUSG00000033343|Vega:OTTMUSG00000017813 +17141 Magea5 MGI:MGI:1333838|Ensembl:ENSMUSG00000079349|Vega:OTTMUSG00000019358 +17142 Magea6 MGI:MGI:1333837|Ensembl:ENSMUSG00000063728|Vega:OTTMUSG00000019279 +17143 Magea7-ps MGI:MGI:1333836 +17144 Magea8 MGI:MGI:1333827|Ensembl:ENSMUSG00000079350|Vega:OTTMUSG00000019274 +17145 Mageb1 MGI:MGI:105118|Ensembl:ENSMUSG00000062162|Vega:OTTMUSG00000017975 +17146 Mageb2 MGI:MGI:105117|Ensembl:ENSMUSG00000073069|Vega:OTTMUSG00000017986 +17147 Mageb3 MGI:MGI:105109|Ensembl:ENSMUSG00000074881|Vega:OTTMUSG00000015439 +17149 Magoh MGI:MGI:1330312|Ensembl:ENSMUSG00000028609|Vega:OTTMUSG00000009191 +17150 Mfap2 MGI:MGI:99559|Ensembl:ENSMUSG00000060572|Vega:OTTMUSG00000010084 +17151 Ccndbp1 MGI:MGI:109595|Ensembl:ENSMUSG00000023572|Vega:OTTMUSG00000015966 +17152 Mak MGI:MGI:96913|Ensembl:ENSMUSG00000021363 +17153 Mal MGI:MGI:892970|Ensembl:ENSMUSG00000027375|Vega:OTTMUSG00000016065 +17155 Man1a MGI:MGI:104677|Ensembl:ENSMUSG00000003746|Vega:OTTMUSG00000024597 +17156 Man1a2 MGI:MGI:104676|Ensembl:ENSMUSG00000008763|Vega:OTTMUSG00000007027 +17158 Man2a1 MGI:MGI:104669|Ensembl:ENSMUSG00000024085|Vega:OTTMUSG00000036800 +17159 Man2b1 MGI:MGI:107286|Ensembl:ENSMUSG00000005142|Vega:OTTMUSG00000061404 +17160 Man2b2 MGI:MGI:1195262|Ensembl:ENSMUSG00000029119|Vega:OTTMUSG00000024727 +17161 Maoa MGI:MGI:96915|Ensembl:ENSMUSG00000025037|Vega:OTTMUSG00000016928 +17164 Mapkapk2 MGI:MGI:109298|Ensembl:ENSMUSG00000016528|Vega:OTTMUSG00000049116 +17165 Mapkapk5 MGI:MGI:1333110|Ensembl:ENSMUSG00000029454|Ensembl:ENSMUSG00000105340|Vega:OTTMUSG00000023483|Vega:OTTMUSG00000054136 +17167 Marco MGI:MGI:1309998|Ensembl:ENSMUSG00000026390|Vega:OTTMUSG00000049075 +17168 Nprl3 MGI:MGI:109258|Ensembl:ENSMUSG00000020289|Vega:OTTMUSG00000005378 +17169 Mark3 MGI:MGI:1341865|Ensembl:ENSMUSG00000007411 +17171 Mas1 MGI:MGI:96918|Ensembl:ENSMUSG00000068037|Vega:OTTMUSG00000034919 +17172 Ascl1 MGI:MGI:96919|Ensembl:ENSMUSG00000020052 +17173 Ascl2 MGI:MGI:96920|Ensembl:ENSMUSG00000009248|Vega:OTTMUSG00000018799 +17174 Masp1 MGI:MGI:88492|Ensembl:ENSMUSG00000022887 +17175 Masp2 MGI:MGI:1330832|Ensembl:ENSMUSG00000028979|Vega:OTTMUSG00000010952 +17178 Fxyd3 MGI:MGI:107497|Ensembl:ENSMUSG00000057092|Vega:OTTMUSG00000036040 +17179 Matk MGI:MGI:99259|Ensembl:ENSMUSG00000004933|Vega:OTTMUSG00000030346 +17180 Matn1 MGI:MGI:106591|Ensembl:ENSMUSG00000040533|Vega:OTTMUSG00000009592 +17181 Matn2 MGI:MGI:109613|Ensembl:ENSMUSG00000022324 +17182 Matn3 MGI:MGI:1328350|Ensembl:ENSMUSG00000020583|Vega:OTTMUSG00000030695 +17183 Matn4 MGI:MGI:1328314|Ensembl:ENSMUSG00000016995|Vega:OTTMUSG00000001183 +17184 Matr3 MGI:MGI:1298379|Ensembl:ENSMUSG00000037236|Vega:OTTMUSG00000045440 +17185 Matr3-ps1 MGI:MGI:1298409 +17186 Matr3-ps2 MGI:MGI:1298410 +17187 Max MGI:MGI:96921|Ensembl:ENSMUSG00000059436 +17188 Maz MGI:MGI:1338823|Ensembl:ENSMUSG00000030678|Vega:OTTMUSG00000058492 +17189 Mb MGI:MGI:96922|Ensembl:ENSMUSG00000018893 +17190 Mbd1 MGI:MGI:1333811|Ensembl:ENSMUSG00000024561 +17191 Mbd2 MGI:MGI:1333813|Ensembl:ENSMUSG00000024513|Vega:OTTMUSG00000027673 +17192 Mbd3 MGI:MGI:1333812|Ensembl:ENSMUSG00000035478|Vega:OTTMUSG00000019125 +17193 Mbd4 MGI:MGI:1333850|Ensembl:ENSMUSG00000030322|Vega:OTTMUSG00000023174 +17194 Mbl1 MGI:MGI:96923|Ensembl:ENSMUSG00000037780 +17195 Mbl2 MGI:MGI:96924|Ensembl:ENSMUSG00000024863 +17196 Mbp MGI:MGI:96925|Ensembl:ENSMUSG00000041607|Vega:OTTMUSG00000016316 +17198 mc MGI:MGI:96927 +17199 Mc1r MGI:MGI:99456|Ensembl:ENSMUSG00000074037|Vega:OTTMUSG00000051105 +17200 Mc2r MGI:MGI:96928|Ensembl:ENSMUSG00000045569 +17201 Mc3r MGI:MGI:96929|Ensembl:ENSMUSG00000038537|Vega:OTTMUSG00000016156 +17202 Mc4r MGI:MGI:99457|Ensembl:ENSMUSG00000047259 +17203 Mc5r MGI:MGI:99420|Ensembl:ENSMUSG00000007480 +17207 Mcf2l MGI:MGI:103263|Ensembl:ENSMUSG00000031442|Vega:OTTMUSG00000020608 +17210 Mcl1 MGI:MGI:101769|Ensembl:ENSMUSG00000038612|Vega:OTTMUSG00000053009 +17215 Mcm3 MGI:MGI:101845|Ensembl:ENSMUSG00000041859|Vega:OTTMUSG00000048358 +17216 Mcm2 MGI:MGI:105380|Ensembl:ENSMUSG00000002870|Vega:OTTMUSG00000057511 +17217 Mcm4 MGI:MGI:103199|Ensembl:ENSMUSG00000022673 +17218 Mcm5 MGI:MGI:103197|Ensembl:ENSMUSG00000005410|Vega:OTTMUSG00000062027 +17219 Mcm6 MGI:MGI:1298227|Ensembl:ENSMUSG00000026355|Vega:OTTMUSG00000049360 +17220 Mcm7 MGI:MGI:1298398|Ensembl:ENSMUSG00000029730|Vega:OTTMUSG00000022672 +17221 Cd46 MGI:MGI:1203290|Ensembl:ENSMUSG00000016493|Vega:OTTMUSG00000034956 +17222 Anapc1 MGI:MGI:103097|Ensembl:ENSMUSG00000014355|Vega:OTTMUSG00000015352 +17223 Mcpt-ps1 MGI:MGI:102769 +17224 Mcpt1 MGI:MGI:96937|Ensembl:ENSMUSG00000022227 +17225 Mcpt2 MGI:MGI:96938|Ensembl:ENSMUSG00000022226 +17227 Mcpt4 MGI:MGI:96940|Ensembl:ENSMUSG00000061068 +17228 Cma1 MGI:MGI:96941|Ensembl:ENSMUSG00000022225 +17229 Tpsb2 MGI:MGI:96942|Ensembl:ENSMUSG00000033825 +17231 Mcpt8 MGI:MGI:1261780|Ensembl:ENSMUSG00000022157 +17232 Mcpt9 MGI:MGI:1194491|Ensembl:ENSMUSG00000071361 +17233 Mcptl MGI:MGI:102792 +17235 Smcp MGI:MGI:96945 +17236 mct1 MGI:MGI:104870 +17237 Mgrn1 MGI:MGI:2447670|Ensembl:ENSMUSG00000022517 +17238 Mdac MGI:MGI:96947 +17240 Mdfi MGI:MGI:107687|Ensembl:ENSMUSG00000032717|Vega:OTTMUSG00000018352 +17242 Mdk MGI:MGI:96949|Ensembl:ENSMUSG00000027239|Vega:OTTMUSG00000014364 +17243 Mdk-ps1 MGI:MGI:103029 +17245 Mdm1 MGI:MGI:96951|Ensembl:ENSMUSG00000020212 +17246 Mdm2 MGI:MGI:96952|Ensembl:ENSMUSG00000020184|Vega:OTTMUSG00000020921 +17248 Mdm4 MGI:MGI:107934|Ensembl:ENSMUSG00000054387|Vega:OTTMUSG00000049638 +17250 Abcc1 MGI:MGI:102676|Ensembl:ENSMUSG00000023088|Vega:OTTMUSG00000027051 +17252 Rdh11 MGI:MGI:102581|Ensembl:ENSMUSG00000066441|Vega:OTTMUSG00000034945 +17254 Slc3a2 MGI:MGI:96955|Ensembl:ENSMUSG00000010095|Vega:OTTMUSG00000057838 +17255 mea MGI:MGI:96956 +17256 Mea1 MGI:MGI:96957|Ensembl:ENSMUSG00000002768 +17257 Mecp2 MGI:MGI:99918|Ensembl:ENSMUSG00000031393|Vega:OTTMUSG00000017654 +17258 Mef2a MGI:MGI:99532|Ensembl:ENSMUSG00000030557|Vega:OTTMUSG00000021127 +17259 Mef2b MGI:MGI:104526|Ensembl:ENSMUSG00000079033|Vega:OTTMUSG00000022207 +17260 Mef2c MGI:MGI:99458|Ensembl:ENSMUSG00000005583|Vega:OTTMUSG00000044481 +17261 Mef2d MGI:MGI:99533|Ensembl:ENSMUSG00000001419|Vega:OTTMUSG00000027132 +17263 Meg3 MGI:MGI:1202886|Ensembl:ENSMUSG00000021268 +17268 Meis1 MGI:MGI:104717|Ensembl:ENSMUSG00000020160|Vega:OTTMUSG00000005212 +17274 Rab8a MGI:MGI:96960|Ensembl:ENSMUSG00000003037|Vega:OTTMUSG00000022245 +17276 Mela MGI:MGI:107565 +17279 Melk MGI:MGI:106924|Ensembl:ENSMUSG00000035683|Vega:OTTMUSG00000006665 +17281 Fyco1 MGI:MGI:107277|Ensembl:ENSMUSG00000025241|Vega:OTTMUSG00000044623 +17283 Men1 MGI:MGI:1316736|Ensembl:ENSMUSG00000024947|Vega:OTTMUSG00000018611 +17285 Meox1 MGI:MGI:103220|Ensembl:ENSMUSG00000001493|Vega:OTTMUSG00000002088 +17286 Meox2 MGI:MGI:103219|Ensembl:ENSMUSG00000036144|Vega:OTTMUSG00000037527 +17287 Mep1a MGI:MGI:96963|Ensembl:ENSMUSG00000023914|Vega:OTTMUSG00000029860 +17288 Mep1b MGI:MGI:96964|Ensembl:ENSMUSG00000024313 +17289 Mertk MGI:MGI:96965|Ensembl:ENSMUSG00000014361|Vega:OTTMUSG00000015353 +17292 Mesp1 MGI:MGI:107785|Ensembl:ENSMUSG00000030544|Vega:OTTMUSG00000024965 +17293 Mesp2 MGI:MGI:1096325|Ensembl:ENSMUSG00000030543|Vega:OTTMUSG00000058591 +17294 Mest MGI:MGI:96968|Ensembl:ENSMUSG00000051855|Vega:OTTMUSG00000014405 +17295 Met MGI:MGI:96969|Ensembl:ENSMUSG00000009376|Vega:OTTMUSG00000024024 +17299 Mettl1 MGI:MGI:1339986|Ensembl:ENSMUSG00000006732|Vega:OTTMUSG00000030570 +17300 Foxc1 MGI:MGI:1347466|Ensembl:ENSMUSG00000050295|Vega:OTTMUSG00000000725 +17301 Foxd2 MGI:MGI:1347471|Ensembl:ENSMUSG00000055210|Vega:OTTMUSG00000008587 +17304 Mfge8 MGI:MGI:102768|Ensembl:ENSMUSG00000030605|Vega:OTTMUSG00000058555 +17305 Mfng MGI:MGI:1095404|Ensembl:ENSMUSG00000018169|Vega:OTTMUSG00000021012 +17306 Sypl2 MGI:MGI:1328311|Ensembl:ENSMUSG00000027887|Vega:OTTMUSG00000007181 +17308 Mgat1 MGI:MGI:96973|Ensembl:ENSMUSG00000020346|Vega:OTTMUSG00000005541 +17309 Mgat3 MGI:MGI:104532|Ensembl:ENSMUSG00000042428 +17311 Kitl MGI:MGI:96974|Ensembl:ENSMUSG00000019966|Vega:OTTMUSG00000020799 +17312 Clec10a MGI:MGI:96975|Ensembl:ENSMUSG00000000318|Vega:OTTMUSG00000006033 +17313 Mgp MGI:MGI:96976|Ensembl:ENSMUSG00000030218|Vega:OTTMUSG00000057425 +17314 Mgmt MGI:MGI:96977|Ensembl:ENSMUSG00000054612|Vega:OTTMUSG00000060300 +17316 mic MGI:MGI:96980 +17318 Mid1 MGI:MGI:1100537|Ensembl:ENSMUSG00000035299|Vega:OTTMUSG00000019599 +17319 Mif MGI:MGI:96982|Ensembl:ENSMUSG00000033307 +17329 Cxcl9 MGI:MGI:1352449|Ensembl:ENSMUSG00000029417|Vega:OTTMUSG00000055603 +17330 Minpp1 MGI:MGI:1336159|Ensembl:ENSMUSG00000024896 +17331 Minpp1-ps MGI:MGI:1336190 +17339 Mip MGI:MGI:96990|Ensembl:ENSMUSG00000025389|Vega:OTTMUSG00000024337 +17341 Bhlha15 MGI:MGI:891976|Ensembl:ENSMUSG00000052271|Vega:OTTMUSG00000025580 +17342 Mitf MGI:MGI:104554|Ensembl:ENSMUSG00000035158|Vega:OTTMUSG00000023284 +17344 Pias2 MGI:MGI:1096566|Ensembl:ENSMUSG00000025423 +17345 Mki67 MGI:MGI:106035|Ensembl:ENSMUSG00000031004|Vega:OTTMUSG00000060275 +17346 Mknk1 MGI:MGI:894316|Ensembl:ENSMUSG00000028708|Vega:OTTMUSG00000008696 +17347 Mknk2 MGI:MGI:894279|Ensembl:ENSMUSG00000020190|Vega:OTTMUSG00000054816 +17349 Mlf1 MGI:MGI:1341819|Ensembl:ENSMUSG00000048416|Vega:OTTMUSG00000022658 +17350 Mlh1 MGI:MGI:101938|Ensembl:ENSMUSG00000032498|Vega:OTTMUSG00000031784 +17354 Mllt10 MGI:MGI:1329038|Ensembl:ENSMUSG00000026743|Vega:OTTMUSG00000011456 +17355 Aff1 MGI:MGI:1100819|Ensembl:ENSMUSG00000029313|Vega:OTTMUSG00000022037 +17356 Afdn MGI:MGI:1314653|Ensembl:ENSMUSG00000068036|Vega:OTTMUSG00000029503 +17357 Marcksl1 MGI:MGI:97143|Ensembl:ENSMUSG00000047945|Vega:OTTMUSG00000009665 +17364 Trpm1 MGI:MGI:1330305|Ensembl:ENSMUSG00000030523|Vega:OTTMUSG00000022613 +17380 Mme MGI:MGI:97004|Ensembl:ENSMUSG00000027820|Vega:OTTMUSG00000051889 +17381 Mmp12 MGI:MGI:97005|Ensembl:ENSMUSG00000049723|Vega:OTTMUSG00000027381 +17384 Mmp10 MGI:MGI:97007|Ensembl:ENSMUSG00000047562|Vega:OTTMUSG00000062272 +17385 Mmp11 MGI:MGI:97008|Ensembl:ENSMUSG00000000901|Vega:OTTMUSG00000031859 +17386 Mmp13 MGI:MGI:1340026|Ensembl:ENSMUSG00000050578|Vega:OTTMUSG00000062269 +17387 Mmp14 MGI:MGI:101900|Ensembl:ENSMUSG00000000957|Vega:OTTMUSG00000053900 +17388 Mmp15 MGI:MGI:109320|Ensembl:ENSMUSG00000031790|Vega:OTTMUSG00000027464 +17389 Mmp16 MGI:MGI:1276107|Ensembl:ENSMUSG00000028226|Vega:OTTMUSG00000004650 +17390 Mmp2 MGI:MGI:97009|Ensembl:ENSMUSG00000031740|Vega:OTTMUSG00000061536 +17391 Mmp24 MGI:MGI:1341867|Ensembl:ENSMUSG00000027612|Vega:OTTMUSG00000016131 +17392 Mmp3 MGI:MGI:97010|Ensembl:ENSMUSG00000043613|Vega:OTTMUSG00000062270 +17393 Mmp7 MGI:MGI:103189|Ensembl:ENSMUSG00000018623|Vega:OTTMUSG00000033289 +17394 Mmp8 MGI:MGI:1202395|Ensembl:ENSMUSG00000005800|Vega:OTTMUSG00000062273 +17395 Mmp9 MGI:MGI:97011|Ensembl:ENSMUSG00000017737|Vega:OTTMUSG00000001184 +17418 mn MGI:MGI:97037 +17420 Mnat1 MGI:MGI:106207|Ensembl:ENSMUSG00000021103|Vega:OTTMUSG00000047017 +17423 Ndst2 MGI:MGI:97040|Ensembl:ENSMUSG00000039308 +17424 mneu MGI:MGI:97041 +17425 Foxk1 MGI:MGI:1347488|Ensembl:ENSMUSG00000056493|Vega:OTTMUSG00000054857 +17427 Mns1 MGI:MGI:107933|Ensembl:ENSMUSG00000032221|Vega:OTTMUSG00000044713 +17428 Mnt MGI:MGI:109150|Ensembl:ENSMUSG00000000282|Vega:OTTMUSG00000006185 +17433 Mobp MGI:MGI:108511|Ensembl:ENSMUSG00000032517|Vega:OTTMUSG00000037099 +17434 Mocs2 MGI:MGI:1336894|Ensembl:ENSMUSG00000015536|Vega:OTTMUSG00000036446 +17436 Me1 MGI:MGI:97043|Ensembl:ENSMUSG00000032418|Vega:OTTMUSG00000045046 +17441 Mog MGI:MGI:97435|Ensembl:ENSMUSG00000076439|Vega:OTTMUSG00000014932 +17444 Grap2 MGI:MGI:1333842|Ensembl:ENSMUSG00000042351 +17448 Mdh2 MGI:MGI:97050|Ensembl:ENSMUSG00000019179|Vega:OTTMUSG00000022781 +17449 Mdh1 MGI:MGI:97051|Ensembl:ENSMUSG00000020321|Vega:OTTMUSG00000005249 +17450 Morc1 MGI:MGI:1316740|Ensembl:ENSMUSG00000022652 +17451 Mos MGI:MGI:97052|Ensembl:ENSMUSG00000078365|Vega:OTTMUSG00000004409 +17454 Mov10 MGI:MGI:97054|Ensembl:ENSMUSG00000002227|Vega:OTTMUSG00000022217 +17463 Psmd7 MGI:MGI:1351511|Ensembl:ENSMUSG00000039067|Vega:OTTMUSG00000061936 +17470 Cd200 MGI:MGI:1196990|Ensembl:ENSMUSG00000022661|Vega:OTTMUSG00000035902 +17472 Gbp4 MGI:MGI:97072|Ensembl:ENSMUSG00000079363|Vega:OTTMUSG00000053857 +17474 Clec4d MGI:MGI:1298389|Ensembl:ENSMUSG00000030144|Vega:OTTMUSG00000056550 +17475 Mpdz MGI:MGI:1343489|Ensembl:ENSMUSG00000028402|Vega:OTTMUSG00000009150 +17476 Mpeg1 MGI:MGI:1333743|Ensembl:ENSMUSG00000046805 +17480 Mpl MGI:MGI:97076|Ensembl:ENSMUSG00000006389|Vega:OTTMUSG00000008795 +17523 Mpo MGI:MGI:97137|Ensembl:ENSMUSG00000009350|Vega:OTTMUSG00000001441 +17524 Mpp1 MGI:MGI:105941|Ensembl:ENSMUSG00000031402|Vega:OTTMUSG00000020789 +17527 Mpv17 MGI:MGI:97138|Ensembl:ENSMUSG00000107283|Vega:OTTMUSG00000022466 +17528 Mpz MGI:MGI:103177|Ensembl:ENSMUSG00000056569|Vega:OTTMUSG00000021546 +17532 Mras MGI:MGI:1100856|Ensembl:ENSMUSG00000032470|Vega:OTTMUSG00000029468 +17533 Mrc1 MGI:MGI:97142|Ensembl:ENSMUSG00000026712|Vega:OTTMUSG00000011409 +17534 Mrc2 MGI:MGI:107818|Ensembl:ENSMUSG00000020695|Vega:OTTMUSG00000002846 +17535 Mre11a MGI:MGI:1100512|Ensembl:ENSMUSG00000031928|Vega:OTTMUSG00000031684 +17536 Meis2 MGI:MGI:108564|Ensembl:ENSMUSG00000027210|Vega:OTTMUSG00000015219 +17537 Meis3 MGI:MGI:108519|Ensembl:ENSMUSG00000041420|Vega:OTTMUSG00000040095 +17540 Mrvi1 MGI:MGI:1338023|Ensembl:ENSMUSG00000005611|Vega:OTTMUSG00000033851 +17542 Ms10b MGI:MGI:1276579 +17543 Ms10e MGI:MGI:1276582 +17544 Ms10f MGI:MGI:1276581 +17545 Ms10j MGI:MGI:1276516 +17546 Ms10k MGI:MGI:1276517 +17547 Ms10m MGI:MGI:1276519 +17600 Ms18 MGI:MGI:1321132 +17606 Ms24 MGI:MGI:1321074 +17608 Ms26 MGI:MGI:1321135 +17611 Ms30 MGI:MGI:1321145 +17613 Ms35 MGI:MGI:1321146 +17616 Ms38 MGI:MGI:1321143 +17617 Ms39 MGI:MGI:1321142 +17620 Ms41 MGI:MGI:1321100 +17622 Ms44 MGI:MGI:1321095 +17623 Ms45 MGI:MGI:1321096 +17625 Ms47 MGI:MGI:1321098 +17626 Ms48 MGI:MGI:1321150 +17627 Ms49 MGI:MGI:1321094 +17628 Ms5 MGI:MGI:1321085 +17629 Ms52 MGI:MGI:1321109 +17631 Ms54 MGI:MGI:1321107 +17634 Ms57 MGI:MGI:1321104 +17635 Ms58 MGI:MGI:1321103 +17644 Ms60 MGI:MGI:1321118 +17647 Ms63 MGI:MGI:1321117 +17652 Ms69 MGI:MGI:1321113 +17653 Ms6hm MGI:MGI:97162 +17654 Ms6hm2 MGI:MGI:97163 +17658 Ms71 MGI:MGI:1321114 +17659 Ms73 MGI:MGI:1321115 +17664 Ms80 MGI:MGI:1321071 +17671 Ms9 MGI:MGI:1321081 +17681 Msc MGI:MGI:1333884|Ensembl:ENSMUSG00000025930|Vega:OTTMUSG00000049183 +17684 Cited2 MGI:MGI:1306784|Ensembl:ENSMUSG00000039910 +17685 Msh2 MGI:MGI:101816|Ensembl:ENSMUSG00000024151|Vega:OTTMUSG00000038134 +17686 Msh3 MGI:MGI:109519|Ensembl:ENSMUSG00000014850|Vega:OTTMUSG00000047254 +17687 Msh5 MGI:MGI:1329021|Ensembl:ENSMUSG00000007035|Vega:OTTMUSG00000037144 +17688 Msh6 MGI:MGI:1343961|Ensembl:ENSMUSG00000005370 +17690 Msi1 MGI:MGI:107376|Ensembl:ENSMUSG00000054256|Vega:OTTMUSG00000014661 +17691 Sik1 MGI:MGI:104754|Ensembl:ENSMUSG00000024042 +17692 Msl3 MGI:MGI:1341851|Ensembl:ENSMUSG00000031358|Vega:OTTMUSG00000019558 +17695 Msmb MGI:MGI:97166|Ensembl:ENSMUSG00000021907|Vega:OTTMUSG00000032536 +17698 Msn MGI:MGI:97167|Ensembl:ENSMUSG00000031207|Vega:OTTMUSG00000018161 +17700 Mstn MGI:MGI:95691|Ensembl:ENSMUSG00000026100|Vega:OTTMUSG00000046890 +17701 Msx1 MGI:MGI:97168|Ensembl:ENSMUSG00000048450|Vega:OTTMUSG00000021309 +17702 Msx2 MGI:MGI:97169|Ensembl:ENSMUSG00000021469|Vega:OTTMUSG00000020950 +17703 Msx3 MGI:MGI:106587|Ensembl:ENSMUSG00000025469|Vega:OTTMUSG00000037529 +17705 ATP6 MGI:MGI:99927 +17706 ATP8 MGI:MGI:99926 +17708 COX1 MGI:MGI:102504 +17709 COX2 MGI:MGI:102503 +17710 COX3 MGI:MGI:102502 +17711 CYTB MGI:MGI:102501 +17713 Grpel1 MGI:MGI:1334417|Ensembl:ENSMUSG00000029198|Vega:OTTMUSG00000027992 +17714 Grpel2 MGI:MGI:1334416|Ensembl:ENSMUSG00000024580 +17716 ND1 MGI:MGI:101787 +17717 ND2 MGI:MGI:102500 +17718 ND3 MGI:MGI:102499 +17719 ND4 MGI:MGI:102498 +17720 ND4L MGI:MGI:102497 +17721 ND5 MGI:MGI:102496 +17722 ND6 MGI:MGI:102495 +17724 mt-Rnr1 MGI:MGI:102493 +17725 mt-Rnr2 MGI:MGI:102492 +17726 TrnA MGI:MGI:102491 +17727 TrnC MGI:MGI:102490 +17728 TrnD MGI:MGI:102489 +17729 TrnE MGI:MGI:102488 +17730 TrnF MGI:MGI:102487 +17731 TrnG MGI:MGI:102486 +17732 TrnH MGI:MGI:102485 +17733 TrnI MGI:MGI:102484 +17734 TrnK MGI:MGI:102483 +17735 TrnL1 MGI:MGI:102482 +17736 TrnL2 MGI:MGI:102481 +17737 TrnM MGI:MGI:102480 +17738 TrnN MGI:MGI:102479 +17739 TrnP MGI:MGI:102478 +17740 TrnQ MGI:MGI:102477 +17741 TrnR MGI:MGI:102476 +17742 TrnS1 MGI:MGI:102475 +17743 TrnS2 MGI:MGI:102474 +17744 TrnT MGI:MGI:102473 +17745 TrnV MGI:MGI:102472 +17746 TrnW MGI:MGI:102471 +17747 TrnY MGI:MGI:102470 +17748 Mt1 MGI:MGI:97171|Ensembl:ENSMUSG00000031765|Vega:OTTMUSG00000061619 +17749 Polr2k MGI:MGI:102725|Ensembl:ENSMUSG00000045996|Vega:OTTMUSG00000042372 +17750 Mt2 MGI:MGI:97172|Ensembl:ENSMUSG00000031762|Vega:OTTMUSG00000061618 +17751 Mt3 MGI:MGI:97173|Ensembl:ENSMUSG00000031760|Vega:OTTMUSG00000061607 +17752 Mt4 MGI:MGI:99692|Ensembl:ENSMUSG00000031757|Vega:OTTMUSG00000061606 +17754 Map1a MGI:MGI:1306776|Ensembl:ENSMUSG00000027254|Vega:OTTMUSG00000015225 +17755 Map1b MGI:MGI:1306778|Ensembl:ENSMUSG00000052727 +17756 Map2 MGI:MGI:97175|Ensembl:ENSMUSG00000015222|Vega:OTTMUSG00000016448 +17758 Map4 MGI:MGI:97178|Ensembl:ENSMUSG00000032479|Vega:OTTMUSG00000035845 +17760 Map6 MGI:MGI:1201690|Ensembl:ENSMUSG00000055407|Vega:OTTMUSG00000031150 +17761 Map7 MGI:MGI:1328328|Ensembl:ENSMUSG00000019996|Vega:OTTMUSG00000063802 +17762 Mapt MGI:MGI:97180|Ensembl:ENSMUSG00000018411|Vega:OTTMUSG00000003153 +17763 Mtcp1 MGI:MGI:102699|Ensembl:ENSMUSG00000031200|Vega:OTTMUSG00000034284 +17764 Mtf1 MGI:MGI:101786|Ensembl:ENSMUSG00000028890|Vega:OTTMUSG00000009170 +17765 Mtf2 MGI:MGI:105050|Ensembl:ENSMUSG00000029267|Vega:OTTMUSG00000021413 +17766 Nudt1 MGI:MGI:109280|Ensembl:ENSMUSG00000036639|Vega:OTTMUSG00000025895 +17768 Mthfd2 MGI:MGI:1338850|Ensembl:ENSMUSG00000005667|Vega:OTTMUSG00000023127 +17769 Mthfr MGI:MGI:106639|Ensembl:ENSMUSG00000029009|Vega:OTTMUSG00000010193 +17771 Tesmin MGI:MGI:1340029|Ensembl:ENSMUSG00000024905|Vega:OTTMUSG00000033866 +17772 Mtm1 MGI:MGI:1099452|Ensembl:ENSMUSG00000031337|Vega:OTTMUSG00000017829 +17773 Mtnr1a MGI:MGI:102967|Ensembl:ENSMUSG00000054764|Vega:OTTMUSG00000034046 +17775 Laptm4a MGI:MGI:108017|Ensembl:ENSMUSG00000020585|Vega:OTTMUSG00000042362 +17776 Mast2 MGI:MGI:894676|Ensembl:ENSMUSG00000003810|Vega:OTTMUSG00000009403 +17777 Mttp MGI:MGI:106926|Ensembl:ENSMUSG00000028158|Vega:OTTMUSG00000052744 +17807 Mtv43 MGI:MGI:97212 +17826 Fam89b MGI:MGI:106595|Ensembl:ENSMUSG00000024939|Vega:OTTMUSG00000035064 +17827 Mtx1 MGI:MGI:103025|Ensembl:ENSMUSG00000064068|Vega:OTTMUSG00000029761 +17828 Bloc1s5 MGI:MGI:2178598|Ensembl:ENSMUSG00000038982 +17829 Muc1 MGI:MGI:97231|Ensembl:ENSMUSG00000042784|Vega:OTTMUSG00000020275 +17830 Prol1 MGI:MGI:107496|Ensembl:ENSMUSG00000064156|Vega:OTTMUSG00000055383 +17831 Muc2 MGI:MGI:1339364 +17833 Muc5ac MGI:MGI:104697|Ensembl:ENSMUSG00000037974|Vega:OTTMUSG00000033677 +17834 Muervc1 MGI:MGI:1339960 +17835 Mug-ps1 MGI:MGI:99838|Ensembl:ENSMUSG00000101397 +17836 Mug1 MGI:MGI:99837|Ensembl:ENSMUSG00000059908|Vega:OTTMUSG00000033687 +17837 Mug2 MGI:MGI:99836|Ensembl:ENSMUSG00000030131|Vega:OTTMUSG00000042408 +17840 Mup1 MGI:MGI:97233|Ensembl:ENSMUSG00000078683|Vega:OTTMUSG00000007426 +17841 Mup2 MGI:MGI:97234|Ensembl:ENSMUSG00000078688|Vega:OTTMUSG00000007427 +17842 Mup3 MGI:MGI:97235|Ensembl:ENSMUSG00000066154|Vega:OTTMUSG00000007481 +17843 Mup4 MGI:MGI:97236|Ensembl:ENSMUSG00000041333|Vega:OTTMUSG00000007405 +17844 Mup5 MGI:MGI:104974|Ensembl:ENSMUSG00000058523|Vega:OTTMUSG00000007482 +17846 Commd1 MGI:MGI:109474|Ensembl:ENSMUSG00000051355|Vega:OTTMUSG00000005270 +17847 Usp34 MGI:MGI:109473|Ensembl:ENSMUSG00000056342|Vega:OTTMUSG00000005281 +17848 Murrs MGI:MGI:1339997 +17849 Murvy MGI:MGI:97238 +17850 Mut MGI:MGI:97239|Ensembl:ENSMUSG00000023921 +17851 mut1 MGI:MGI:97240 +17852 mut2 MGI:MGI:97241 +17855 Mvk MGI:MGI:107624|Ensembl:ENSMUSG00000041939|Vega:OTTMUSG00000014479 +17857 Mx1 MGI:MGI:97243|Ensembl:ENSMUSG00000000386|Vega:OTTMUSG00000016636 +17858 Mx2 MGI:MGI:97244|Ensembl:ENSMUSG00000023341|Vega:OTTMUSG00000047542 +17859 Mxi1 MGI:MGI:97245|Ensembl:ENSMUSG00000025025 +17863 Myb MGI:MGI:97249|Ensembl:ENSMUSG00000019982|Vega:OTTMUSG00000046559 +17864 Mybl1 MGI:MGI:99925|Ensembl:ENSMUSG00000025912|Vega:OTTMUSG00000034736 +17865 Mybl2 MGI:MGI:101785|Ensembl:ENSMUSG00000017861|Vega:OTTMUSG00000001166 +17868 Mybpc3 MGI:MGI:102844|Ensembl:ENSMUSG00000002100|Vega:OTTMUSG00000014369 +17869 Myc MGI:MGI:97250|Ensembl:ENSMUSG00000022346|Vega:OTTMUSG00000034892 +17870 Mycs MGI:MGI:1332242|Ensembl:ENSMUSG00000044597|Vega:OTTMUSG00000016436 +17872 Ppp1r15a MGI:MGI:1927072|Ensembl:ENSMUSG00000040435|Vega:OTTMUSG00000024467 +17873 Gadd45b MGI:MGI:107776|Ensembl:ENSMUSG00000015312 +17874 Myd88 MGI:MGI:108005|Ensembl:ENSMUSG00000032508|Vega:OTTMUSG00000016655 +17876 Myef2 MGI:MGI:104592|Ensembl:ENSMUSG00000027201|Vega:OTTMUSG00000015333 +17877 Myf5 MGI:MGI:97252|Ensembl:ENSMUSG00000000435 +17878 Myf6 MGI:MGI:97253|Ensembl:ENSMUSG00000035923 +17879 Myh1 MGI:MGI:1339711|Ensembl:ENSMUSG00000056328|Vega:OTTMUSG00000005918 +17880 Myh11 MGI:MGI:102643|Ensembl:ENSMUSG00000018830 +17882 Myh2 MGI:MGI:1339710|Ensembl:ENSMUSG00000033196|Vega:OTTMUSG00000005919 +17883 Myh3 MGI:MGI:1339709|Ensembl:ENSMUSG00000020908|Vega:OTTMUSG00000005920 +17884 Myh4 MGI:MGI:1339713|Ensembl:ENSMUSG00000057003|Vega:OTTMUSG00000005921 +17885 Myh8 MGI:MGI:1339712|Ensembl:ENSMUSG00000055775|Vega:OTTMUSG00000005922 +17886 Myh9 MGI:MGI:107717|Ensembl:ENSMUSG00000022443|Vega:OTTMUSG00000016428 +17888 Myh6 MGI:MGI:97255|Ensembl:ENSMUSG00000040752|Vega:OTTMUSG00000016384 +17895 Myk103 MGI:MGI:97266 +17896 Myl4 MGI:MGI:97267|Ensembl:ENSMUSG00000061086|Vega:OTTMUSG00000003179 +17897 Myl3 MGI:MGI:97268|Ensembl:ENSMUSG00000059741|Vega:OTTMUSG00000016497 +17898 Myl7 MGI:MGI:107495|Ensembl:ENSMUSG00000020469|Vega:OTTMUSG00000005104 +17901 Myl1 MGI:MGI:97269|Ensembl:ENSMUSG00000061816|Vega:OTTMUSG00000026242 +17902 Mylf-ps MGI:MGI:97270 +17904 Myl6 MGI:MGI:109318|Ensembl:ENSMUSG00000090841 +17906 Myl2 MGI:MGI:97272|Ensembl:ENSMUSG00000013936|Vega:OTTMUSG00000024649 +17907 Mylpf MGI:MGI:97273|Ensembl:ENSMUSG00000030672|Vega:OTTMUSG00000023131 +17909 Myo10 MGI:MGI:107716|Ensembl:ENSMUSG00000022272|Vega:OTTMUSG00000020342 +17910 Myo15 MGI:MGI:1261811|Ensembl:ENSMUSG00000042678|Vega:OTTMUSG00000005818 +17912 Myo1b MGI:MGI:107752|Ensembl:ENSMUSG00000018417|Vega:OTTMUSG00000016470 +17913 Myo1c MGI:MGI:106612|Ensembl:ENSMUSG00000017774|Vega:OTTMUSG00000006212 +17916 Myo1f MGI:MGI:107711|Ensembl:ENSMUSG00000024300|Vega:OTTMUSG00000037201 +17918 Myo5a MGI:MGI:105976|Ensembl:ENSMUSG00000034593|Vega:OTTMUSG00000016492 +17919 Myo5b MGI:MGI:106598|Ensembl:ENSMUSG00000025885|Vega:OTTMUSG00000029560 +17920 Myo6 MGI:MGI:104785|Ensembl:ENSMUSG00000033577|Vega:OTTMUSG00000017558 +17921 Myo7a MGI:MGI:104510|Ensembl:ENSMUSG00000030761|Vega:OTTMUSG00000017631 +17922 Myo7b MGI:MGI:107709|Ensembl:ENSMUSG00000024388|Vega:OTTMUSG00000033977 +17925 Myo9b MGI:MGI:106624|Ensembl:ENSMUSG00000004677|Vega:OTTMUSG00000062152 +17926 Myoc MGI:MGI:1202864|Ensembl:ENSMUSG00000026697|Vega:OTTMUSG00000051917 +17927 Myod1 MGI:MGI:97275|Ensembl:ENSMUSG00000009471|Vega:OTTMUSG00000058657 +17928 Myog MGI:MGI:97276|Ensembl:ENSMUSG00000026459|Vega:OTTMUSG00000049677 +17929 Myom1 MGI:MGI:1341430|Ensembl:ENSMUSG00000024049 +17930 Myom2 MGI:MGI:1328358|Ensembl:ENSMUSG00000031461|Vega:OTTMUSG00000016822 +17931 Ppp1r12a MGI:MGI:1309528|Ensembl:ENSMUSG00000019907 +17932 Myt1 MGI:MGI:1100535|Ensembl:ENSMUSG00000010505|Vega:OTTMUSG00000016812 +17933 Myt1l MGI:MGI:1100511|Ensembl:ENSMUSG00000061911 +17936 Nab1 MGI:MGI:107564|Ensembl:ENSMUSG00000002881|Vega:OTTMUSG00000035900 +17937 Nab2 MGI:MGI:107563|Ensembl:ENSMUSG00000025402|Vega:OTTMUSG00000031880 +17938 Naca MGI:MGI:106095|Ensembl:ENSMUSG00000061315 +17939 Naga MGI:MGI:1261422|Ensembl:ENSMUSG00000022453 +17940 Naip1 MGI:MGI:1298223|Ensembl:ENSMUSG00000021640 +17941 Naip1-rs1 MGI:MGI:109439 +17948 Naip2 MGI:MGI:1298226|Ensembl:ENSMUSG00000078945|Vega:OTTMUSG00000028711 +17950 Naip4 MGI:MGI:1298221 +17951 Naip5 MGI:MGI:1298220|Ensembl:ENSMUSG00000071203|Vega:OTTMUSG00000028712 +17952 Naip6 MGI:MGI:1298222|Ensembl:ENSMUSG00000078942|Vega:OTTMUSG00000028714 +17954 Nap1l2 MGI:MGI:106654|Ensembl:ENSMUSG00000082229|Vega:OTTMUSG00000018175 +17955 Nap1l4 MGI:MGI:1316687|Ensembl:ENSMUSG00000059119|Vega:OTTMUSG00000060029 +17957 Napb MGI:MGI:104562|Ensembl:ENSMUSG00000027438|Vega:OTTMUSG00000015716 +17960 Nat1 MGI:MGI:97279|Ensembl:ENSMUSG00000025588|Vega:OTTMUSG00000061937 +17961 Nat2 MGI:MGI:109201|Ensembl:ENSMUSG00000051147|Vega:OTTMUSG00000061938 +17962 Nat3 MGI:MGI:102537|Ensembl:ENSMUSG00000056426|Vega:OTTMUSG00000061953 +17965 Nbl1 MGI:MGI:104591|Ensembl:ENSMUSG00000041120|Vega:OTTMUSG00000009896 +17966 Nbr1 MGI:MGI:108498|Ensembl:ENSMUSG00000017119|Vega:OTTMUSG00000002872 +17967 Ncam1 MGI:MGI:97281|Ensembl:ENSMUSG00000039542|Vega:OTTMUSG00000052150 +17968 Ncam2 MGI:MGI:97282|Ensembl:ENSMUSG00000022762|Vega:OTTMUSG00000014960 +17969 Ncf1 MGI:MGI:97283|Ensembl:ENSMUSG00000015950|Vega:OTTMUSG00000020372 +17970 Ncf2 MGI:MGI:97284|Ensembl:ENSMUSG00000026480|Vega:OTTMUSG00000049696 +17972 Ncf4 MGI:MGI:109186|Ensembl:ENSMUSG00000071715|Vega:OTTMUSG00000028142 +17973 Nck1 MGI:MGI:109601|Ensembl:ENSMUSG00000032475|Vega:OTTMUSG00000021049 +17974 Nck2 MGI:MGI:1306821|Ensembl:ENSMUSG00000066877|Vega:OTTMUSG00000021065 +17975 Ncl MGI:MGI:97286|Ensembl:ENSMUSG00000026234|Vega:OTTMUSG00000048094 +17977 Ncoa1 MGI:MGI:1276523|Ensembl:ENSMUSG00000020647 +17978 Ncoa2 MGI:MGI:1276533|Ensembl:ENSMUSG00000005886|Vega:OTTMUSG00000021630 +17979 Ncoa3 MGI:MGI:1276535|Ensembl:ENSMUSG00000027678|Vega:OTTMUSG00000001163 +17983 nd MGI:MGI:97289 +17984 Ndn MGI:MGI:97290|Ensembl:ENSMUSG00000033585|Vega:OTTMUSG00000059564 +17986 Ndp MGI:MGI:102570|Ensembl:ENSMUSG00000040138|Vega:OTTMUSG00000016937 +17988 Ndrg1 MGI:MGI:1341799|Ensembl:ENSMUSG00000005125|Vega:OTTMUSG00000035395 +17991 Ndufa2 MGI:MGI:1343103|Ensembl:ENSMUSG00000014294|Vega:OTTMUSG00000042397 +17992 Ndufa4 MGI:MGI:107686|Ensembl:ENSMUSG00000029632|Vega:OTTMUSG00000057021 +17993 Ndufs4 MGI:MGI:1343135|Ensembl:ENSMUSG00000021764 +17995 Ndufv1 MGI:MGI:107851|Ensembl:ENSMUSG00000037916|Vega:OTTMUSG00000034058 +17996 Neb MGI:MGI:97292|Ensembl:ENSMUSG00000026950|Vega:OTTMUSG00000012541 +17997 Nedd1 MGI:MGI:97293|Ensembl:ENSMUSG00000019988|Vega:OTTMUSG00000063852 +17999 Nedd4 MGI:MGI:97297|Ensembl:ENSMUSG00000032216|Vega:OTTMUSG00000044728 +18000 Sept2 MGI:MGI:97298|Ensembl:ENSMUSG00000026276|Ensembl:ENSMUSG00000112508|Vega:OTTMUSG00000021857 +18002 Nedd8 MGI:MGI:97301|Ensembl:ENSMUSG00000010376 +18003 Nedd9 MGI:MGI:97302|Ensembl:ENSMUSG00000021365 +18004 Nek1 MGI:MGI:97303|Ensembl:ENSMUSG00000031644|Vega:OTTMUSG00000031430 +18005 Nek2 MGI:MGI:109359|Ensembl:ENSMUSG00000026622|Vega:OTTMUSG00000027018 +18007 Neo1 MGI:MGI:1097159|Ensembl:ENSMUSG00000032340|Vega:OTTMUSG00000063287 +18008 Nes MGI:MGI:101784|Ensembl:ENSMUSG00000004891|Vega:OTTMUSG00000026661 +18010 Neu1 MGI:MGI:97305|Ensembl:ENSMUSG00000007038|Vega:OTTMUSG00000037276 +18011 Neurl1a MGI:MGI:1334263|Ensembl:ENSMUSG00000006435 +18012 Neurod1 MGI:MGI:1339708|Ensembl:ENSMUSG00000034701|Vega:OTTMUSG00000013310 +18013 Neurod2 MGI:MGI:107755|Ensembl:ENSMUSG00000038255|Vega:OTTMUSG00000002638 +18014 Neurog1 MGI:MGI:107754|Ensembl:ENSMUSG00000048904 +18015 Nf1 MGI:MGI:97306|Ensembl:ENSMUSG00000020716|Vega:OTTMUSG00000000164 +18016 Nf2 MGI:MGI:97307|Ensembl:ENSMUSG00000009073|Vega:OTTMUSG00000005071 +18018 Nfatc1 MGI:MGI:102469|Ensembl:ENSMUSG00000033016 +18019 Nfatc2 MGI:MGI:102463|Ensembl:ENSMUSG00000027544|Vega:OTTMUSG00000016052 +18020 Nfatc2ip MGI:MGI:1329015|Ensembl:ENSMUSG00000030722|Vega:OTTMUSG00000025272 +18021 Nfatc3 MGI:MGI:103296|Ensembl:ENSMUSG00000031902|Vega:OTTMUSG00000061942 +18022 Nfe2 MGI:MGI:97308|Ensembl:ENSMUSG00000058794|Vega:OTTMUSG00000034093 +18023 Nfe2l1 MGI:MGI:99421|Ensembl:ENSMUSG00000038615|Vega:OTTMUSG00000001635 +18024 Nfe2l2 MGI:MGI:108420|Ensembl:ENSMUSG00000015839|Vega:OTTMUSG00000013248 +18025 Nfe2l3 MGI:MGI:1339958|Ensembl:ENSMUSG00000029832|Vega:OTTMUSG00000034271 +18027 Nfia MGI:MGI:108056|Ensembl:ENSMUSG00000028565|Vega:OTTMUSG00000007951 +18028 Nfib MGI:MGI:103188|Ensembl:ENSMUSG00000008575|Vega:OTTMUSG00000000395 +18029 Nfic MGI:MGI:109591|Ensembl:ENSMUSG00000055053|Vega:OTTMUSG00000030419 +18030 Nfil3 MGI:MGI:109495|Ensembl:ENSMUSG00000056749|Vega:OTTMUSG00000020972 +18032 Nfix MGI:MGI:97311|Ensembl:ENSMUSG00000001911|Vega:OTTMUSG00000022188 +18033 Nfkb1 MGI:MGI:97312|Ensembl:ENSMUSG00000028163|Vega:OTTMUSG00000016668 +18034 Nfkb2 MGI:MGI:1099800|Ensembl:ENSMUSG00000025225 +18035 Nfkbia MGI:MGI:104741|Ensembl:ENSMUSG00000021025 +18036 Nfkbib MGI:MGI:104752|Ensembl:ENSMUSG00000030595|Vega:OTTMUSG00000016845 +18037 Nfkbie MGI:MGI:1194908|Ensembl:ENSMUSG00000023947 +18038 Nfkbil1 MGI:MGI:1340031|Ensembl:ENSMUSG00000042419|Vega:OTTMUSG00000031450 +18039 Nefl MGI:MGI:97313|Ensembl:ENSMUSG00000022055|Vega:OTTMUSG00000016377 +18040 Nefm MGI:MGI:97314|Ensembl:ENSMUSG00000022054|Vega:OTTMUSG00000016378 +18041 Nfs1 MGI:MGI:1316706|Ensembl:ENSMUSG00000027618|Vega:OTTMUSG00000016100 +18044 Nfya MGI:MGI:97316|Ensembl:ENSMUSG00000023994|Vega:OTTMUSG00000035112 +18045 Nfyb MGI:MGI:97317|Ensembl:ENSMUSG00000020248|Vega:OTTMUSG00000032747 +18046 Nfyc MGI:MGI:107901|Ensembl:ENSMUSG00000032897|Vega:OTTMUSG00000008852 +18048 Klk1b4 MGI:MGI:97320|Ensembl:ENSMUSG00000066513|Vega:OTTMUSG00000027268 +18049 Ngf MGI:MGI:97321|Ensembl:ENSMUSG00000027859|Vega:OTTMUSG00000054689 +18050 Klk1b3 MGI:MGI:97322|Ensembl:ENSMUSG00000066515|Vega:OTTMUSG00000027267 +18053 Ngfr MGI:MGI:97323|Ensembl:ENSMUSG00000000120|Vega:OTTMUSG00000001661 +18054 Ngp MGI:MGI:105983|Ensembl:ENSMUSG00000032484|Vega:OTTMUSG00000023542 +18071 Nhlh1 MGI:MGI:98481|Ensembl:ENSMUSG00000051251|Vega:OTTMUSG00000033453 +18072 Nhlh2 MGI:MGI:97324|Ensembl:ENSMUSG00000048540|Vega:OTTMUSG00000054680 +18073 Nid1 MGI:MGI:97342|Ensembl:ENSMUSG00000005397 +18074 Nid2 MGI:MGI:1298229|Ensembl:ENSMUSG00000021806 +18080 Nin MGI:MGI:105108|Ensembl:ENSMUSG00000021068|Vega:OTTMUSG00000037170 +18081 Ninj1 MGI:MGI:1196617|Ensembl:ENSMUSG00000037966|Vega:OTTMUSG00000027739 +18082 Nipsnap1 MGI:MGI:1278344|Ensembl:ENSMUSG00000034285|Vega:OTTMUSG00000005074 +18087 Nktr MGI:MGI:97346|Ensembl:ENSMUSG00000032525|Vega:OTTMUSG00000043287 +18088 Nkx2-2 MGI:MGI:97347|Ensembl:ENSMUSG00000027434|Vega:OTTMUSG00000045623 +18089 Nkx2-3 MGI:MGI:97348|Ensembl:ENSMUSG00000044220|Vega:OTTMUSG00000029846 +18091 Nkx2-5 MGI:MGI:97350|Ensembl:ENSMUSG00000015579|Vega:OTTMUSG00000037537 +18092 Nkx2-6 MGI:MGI:97351|Ensembl:ENSMUSG00000044186|Vega:OTTMUSG00000037541 +18094 Nkx2-9 MGI:MGI:1270158|Ensembl:ENSMUSG00000058669|Vega:OTTMUSG00000023061 +18095 Nkx3-1 MGI:MGI:97352|Ensembl:ENSMUSG00000022061|Vega:OTTMUSG00000037540 +18096 Nkx6-1 MGI:MGI:1206039|Ensembl:ENSMUSG00000035187|Vega:OTTMUSG00000037547 +18097 Nlf1 MGI:MGI:97353 +18098 Nlf2 MGI:MGI:97354 +18099 Nlk MGI:MGI:1201387|Ensembl:ENSMUSG00000017376|Vega:OTTMUSG00000000149 +18100 Mrpl40 MGI:MGI:1332635|Ensembl:ENSMUSG00000022706|Vega:OTTMUSG00000026128 +18101 Nmbr MGI:MGI:1100525|Ensembl:ENSMUSG00000019865|Vega:OTTMUSG00000045116 +18102 Nme1 MGI:MGI:97355|Ensembl:ENSMUSG00000037601|Vega:OTTMUSG00000001490 +18103 Nme2 MGI:MGI:97356|Ensembl:ENSMUSG00000020857|Vega:OTTMUSG00000001491 +18104 Nqo1 MGI:MGI:103187|Ensembl:ENSMUSG00000003849|Vega:OTTMUSG00000022884 +18105 Nqo2 MGI:MGI:104513|Ensembl:ENSMUSG00000046949 +18106 Cd244 MGI:MGI:109294|Ensembl:ENSMUSG00000004709|Vega:OTTMUSG00000016914 +18107 Nmt1 MGI:MGI:102579|Ensembl:ENSMUSG00000020936|Vega:OTTMUSG00000003161 +18108 Nmt2 MGI:MGI:1202298|Ensembl:ENSMUSG00000026643|Vega:OTTMUSG00000010789 +18109 Mycn MGI:MGI:97357|Ensembl:ENSMUSG00000037169|Vega:OTTMUSG00000032640 +18111 Nnat MGI:MGI:104716|Ensembl:ENSMUSG00000067786|Vega:OTTMUSG00000016197 +18113 Nnmt MGI:MGI:1099443|Ensembl:ENSMUSG00000032271|Vega:OTTMUSG00000027445 +18114 Rrp1 MGI:MGI:1203500|Ensembl:ENSMUSG00000061032 +18115 Nnt MGI:MGI:109279|Ensembl:ENSMUSG00000025453|Ensembl:ENSMUSG00000113525|Vega:OTTMUSG00000021068 +18117 Emc8 MGI:MGI:1343095|Ensembl:ENSMUSG00000031819|Vega:OTTMUSG00000043012 +18119 Nodal MGI:MGI:97359|Ensembl:ENSMUSG00000037171|Vega:OTTMUSG00000021483 +18120 Mrpl49 MGI:MGI:108180|Ensembl:ENSMUSG00000007338 +18121 Nog MGI:MGI:104327|Ensembl:ENSMUSG00000048616|Vega:OTTMUSG00000001321 +18124 Nr4a3 MGI:MGI:1352457|Ensembl:ENSMUSG00000028341|Vega:OTTMUSG00000006813 +18125 Nos1 MGI:MGI:97360|Ensembl:ENSMUSG00000029361|Vega:OTTMUSG00000016286 +18126 Nos2 MGI:MGI:97361|Ensembl:ENSMUSG00000020826|Vega:OTTMUSG00000000146 +18127 Nos3 MGI:MGI:97362|Ensembl:ENSMUSG00000028978|Vega:OTTMUSG00000024082 +18128 Notch1 MGI:MGI:97363|Ensembl:ENSMUSG00000026923|Vega:OTTMUSG00000012795 +18129 Notch2 MGI:MGI:97364|Ensembl:ENSMUSG00000027878|Vega:OTTMUSG00000053240 +18130 Ints6 MGI:MGI:1202397|Ensembl:ENSMUSG00000035161 +18131 Notch3 MGI:MGI:99460|Ensembl:ENSMUSG00000038146|Vega:OTTMUSG00000030086 +18132 Notch4 MGI:MGI:107471|Ensembl:ENSMUSG00000015468|Vega:OTTMUSG00000020242 +18133 Nov MGI:MGI:109185|Ensembl:ENSMUSG00000037362|Vega:OTTMUSG00000033259 +18139 Zfp638 MGI:MGI:1203484|Ensembl:ENSMUSG00000030016|Vega:OTTMUSG00000057474 +18140 Uhrf1 MGI:MGI:1338889|Ensembl:ENSMUSG00000001228|Vega:OTTMUSG00000021035 +18141 Nup50 MGI:MGI:1351502|Ensembl:ENSMUSG00000016619 +18142 Npas1 MGI:MGI:109205|Ensembl:ENSMUSG00000001988|Vega:OTTMUSG00000060591 +18143 Npas2 MGI:MGI:109232|Ensembl:ENSMUSG00000026077|Vega:OTTMUSG00000036938 +18145 Npc1 MGI:MGI:1097712|Ensembl:ENSMUSG00000024413|Vega:OTTMUSG00000028201 +18146 Npdc1 MGI:MGI:1099802|Ensembl:ENSMUSG00000015094|Vega:OTTMUSG00000012107 +18148 Npm1 MGI:MGI:106184|Ensembl:ENSMUSG00000057113|Vega:OTTMUSG00000005395 +18150 Npm3 MGI:MGI:894653|Ensembl:ENSMUSG00000056209|Vega:OTTMUSG00000022715 +18153 Npn2 MGI:MGI:104972 +18155 Pnoc MGI:MGI:105308|Ensembl:ENSMUSG00000045731 +18158 Nppb MGI:MGI:97368|Ensembl:ENSMUSG00000029019|Vega:OTTMUSG00000010194 +18159 Nppc MGI:MGI:97369|Ensembl:ENSMUSG00000026241|Vega:OTTMUSG00000048101 +18160 Npr1 MGI:MGI:97371|Ensembl:ENSMUSG00000027931|Vega:OTTMUSG00000029513 +18162 Npr3 MGI:MGI:97373|Ensembl:ENSMUSG00000022206 +18163 Ctnnd2 MGI:MGI:1195966|Ensembl:ENSMUSG00000022240 +18164 Nptx1 MGI:MGI:107811|Ensembl:ENSMUSG00000025582|Vega:OTTMUSG00000003985 +18166 Npy1r MGI:MGI:104963|Ensembl:ENSMUSG00000036437|Vega:OTTMUSG00000061842 +18167 Npy2r MGI:MGI:108418|Ensembl:ENSMUSG00000028004|Vega:OTTMUSG00000043302 +18168 Npy5r MGI:MGI:108082|Ensembl:ENSMUSG00000044014|Vega:OTTMUSG00000061841 +18169 Npy6r MGI:MGI:1098590|Ensembl:ENSMUSG00000038071 +18170 nr MGI:MGI:97375 +18171 Nr1i2 MGI:MGI:1337040|Ensembl:ENSMUSG00000022809|Vega:OTTMUSG00000023687 +18173 Slc11a1 MGI:MGI:1345275|Ensembl:ENSMUSG00000026177|Vega:OTTMUSG00000016632 +18174 Slc11a2 MGI:MGI:1345279|Ensembl:ENSMUSG00000023030|Vega:OTTMUSG00000033264 +18175 Nrap MGI:MGI:1098765|Ensembl:ENSMUSG00000049134|Vega:OTTMUSG00000036778 +18176 Nras MGI:MGI:97376|Ensembl:ENSMUSG00000027852|Vega:OTTMUSG00000021269 +18178 Nras-ps2 MGI:MGI:97378 +18181 Nrf1 MGI:MGI:1332235|Ensembl:ENSMUSG00000058440|Vega:OTTMUSG00000014351 +18183 Nrg3 MGI:MGI:1097165|Ensembl:ENSMUSG00000041014|Vega:OTTMUSG00000037129 +18185 Nrl MGI:MGI:102567|Ensembl:ENSMUSG00000040632 +18186 Nrp1 MGI:MGI:106206|Ensembl:ENSMUSG00000025810|Vega:OTTMUSG00000061647 +18187 Nrp2 MGI:MGI:1100492|Ensembl:ENSMUSG00000025969|Vega:OTTMUSG00000002566 +18188 Nrtn MGI:MGI:108417|Ensembl:ENSMUSG00000039481 +18189 Nrxn1 MGI:MGI:1096391|Ensembl:ENSMUSG00000024109|Vega:OTTMUSG00000034567 +18190 Nrxn2 MGI:MGI:1096362|Ensembl:ENSMUSG00000033768|Vega:OTTMUSG00000018624 +18191 Nrxn3 MGI:MGI:1096389|Ensembl:ENSMUSG00000066392|Vega:OTTMUSG00000035299 +18193 Nsd1 MGI:MGI:1276545|Ensembl:ENSMUSG00000021488 +18194 Nsdhl MGI:MGI:1099438|Ensembl:ENSMUSG00000031349|Vega:OTTMUSG00000017843 +18195 Nsf MGI:MGI:104560|Ensembl:ENSMUSG00000034187|Vega:OTTMUSG00000003022 +18196 Nsg1 MGI:MGI:109149|Ensembl:ENSMUSG00000029126|Vega:OTTMUSG00000056100 +18197 Nsg2 MGI:MGI:1202070|Ensembl:ENSMUSG00000020297|Vega:OTTMUSG00000005366 +18198 Musk MGI:MGI:103581|Ensembl:ENSMUSG00000057280|Vega:OTTMUSG00000007438 +18201 Nsmaf MGI:MGI:1341864|Ensembl:ENSMUSG00000028245|Vega:OTTMUSG00000004313 +18202 nt MGI:MGI:1342302 +18203 Ntan1 MGI:MGI:108471|Ensembl:ENSMUSG00000022681|Vega:OTTMUSG00000023679 +18205 Ntf3 MGI:MGI:97380|Ensembl:ENSMUSG00000049107|Vega:OTTMUSG00000056716 +18207 Nthl1 MGI:MGI:1313275|Ensembl:ENSMUSG00000041429 +18208 Ntn1 MGI:MGI:105088|Ensembl:ENSMUSG00000020902|Vega:OTTMUSG00000005943 +18209 Ntn3 MGI:MGI:1341188|Ensembl:ENSMUSG00000036473 +18211 Ntrk1 MGI:MGI:97383|Ensembl:ENSMUSG00000028072|Vega:OTTMUSG00000051890 +18212 Ntrk2 MGI:MGI:97384|Ensembl:ENSMUSG00000055254 +18213 Ntrk3 MGI:MGI:97385|Ensembl:ENSMUSG00000059146|Vega:OTTMUSG00000021139 +18214 Ddr2 MGI:MGI:1345277|Ensembl:ENSMUSG00000026674|Vega:OTTMUSG00000049937 +18216 Ntsr1 MGI:MGI:97386|Ensembl:ENSMUSG00000027568|Vega:OTTMUSG00000016330 +18217 Ntsr2 MGI:MGI:108018|Ensembl:ENSMUSG00000020591 +18218 Dusp8 MGI:MGI:106626|Ensembl:ENSMUSG00000037887|Vega:OTTMUSG00000027242 +18220 Nucb1 MGI:MGI:97388|Ensembl:ENSMUSG00000030824|Vega:OTTMUSG00000024466 +18221 Nudc MGI:MGI:106014|Ensembl:ENSMUSG00000028851|Vega:OTTMUSG00000011151 +18222 Numb MGI:MGI:107423|Ensembl:ENSMUSG00000021224|Vega:OTTMUSG00000031495 +18223 Numbl MGI:MGI:894702|Ensembl:ENSMUSG00000063160|Vega:OTTMUSG00000023785 +18226 Nup62 MGI:MGI:1351500|Ensembl:ENSMUSG00000109511|Vega:OTTMUSG00000021116 +18227 Nr4a2 MGI:MGI:1352456|Ensembl:ENSMUSG00000026826|Vega:OTTMUSG00000012562 +18229 nv MGI:MGI:97389 +18230 Nxn MGI:MGI:109331|Ensembl:ENSMUSG00000020844|Vega:OTTMUSG00000006232 +18231 Nxph1 MGI:MGI:107492|Ensembl:ENSMUSG00000046178|Vega:OTTMUSG00000034245 +18232 Nxph2 MGI:MGI:107491|Ensembl:ENSMUSG00000069132|Vega:OTTMUSG00000012056 +18241 Gpr143 MGI:MGI:107193|Ensembl:ENSMUSG00000025333|Vega:OTTMUSG00000019341 +18242 Oat MGI:MGI:97394|Ensembl:ENSMUSG00000030934|Vega:OTTMUSG00000060664 +18245 Oaz1 MGI:MGI:109433|Ensembl:ENSMUSG00000035242|Vega:OTTMUSG00000042344 +18247 Oaz2 MGI:MGI:109492|Ensembl:ENSMUSG00000040652|Vega:OTTMUSG00000031899 +18249 Obp1a MGI:MGI:1277949|Ensembl:ENSMUSG00000067684|Vega:OTTMUSG00000017890 +18256 Oc90 MGI:MGI:1313269|Ensembl:ENSMUSG00000015001|Vega:OTTMUSG00000024544 +18258 ocd MGI:MGI:97399 +18260 Ocln MGI:MGI:106183|Ensembl:ENSMUSG00000021638|Vega:OTTMUSG00000035055 +18261 Ocm MGI:MGI:97401|Ensembl:ENSMUSG00000029618|Vega:OTTMUSG00000025488 +18263 Odc1 MGI:MGI:97402|Ensembl:ENSMUSG00000011179 +18285 Odf1 MGI:MGI:97424|Ensembl:ENSMUSG00000061923|Vega:OTTMUSG00000029159 +18286 Odf2 MGI:MGI:1098824|Ensembl:ENSMUSG00000026790|Vega:OTTMUSG00000019165 +18287 oe MGI:MGI:97425 +18288 oed MGI:MGI:97426 +18289 oel MGI:MGI:97427 +18290 Ofa MGI:MGI:99880 +18291 Nobox MGI:MGI:108011|Ensembl:ENSMUSG00000029736|Vega:OTTMUSG00000037623 +18292 Sebox MGI:MGI:108012|Ensembl:ENSMUSG00000001103|Vega:OTTMUSG00000000145 +18293 Ogdh MGI:MGI:1098267|Ensembl:ENSMUSG00000020456|Vega:OTTMUSG00000000782 +18294 Ogg1 MGI:MGI:1097693|Ensembl:ENSMUSG00000030271|Vega:OTTMUSG00000022453 +18295 Ogn MGI:MGI:109278|Ensembl:ENSMUSG00000021390 +18299 oh MGI:MGI:97428 +18300 Oit1 MGI:MGI:1201784|Ensembl:ENSMUSG00000021749 +18301 Fxyd5 MGI:MGI:1201785|Ensembl:ENSMUSG00000009687|Vega:OTTMUSG00000034687 +18302 Oit3 MGI:MGI:1201782|Ensembl:ENSMUSG00000009654|Vega:OTTMUSG00000027943 +18303 Oit4 MGI:MGI:1201795 +18305 ol MGI:MGI:97431 +18307 Olfr10 MGI:MGI:107598|Ensembl:ENSMUSG00000100923|Vega:OTTMUSG00000005546 +18310 Olfr13 MGI:MGI:104812|Ensembl:ENSMUSG00000043605|Vega:OTTMUSG00000057730 +18312 Olfr15 MGI:MGI:106182|Ensembl:ENSMUSG00000059043|Vega:OTTMUSG00000058772 +18313 Olfr16 MGI:MGI:106648|Ensembl:ENSMUSG00000037924|Vega:OTTMUSG00000050161 +18314 Olfr17 MGI:MGI:109148|Ensembl:ENSMUSG00000073897|Vega:OTTMUSG00000059736 +18315 Olfr18 MGI:MGI:109317|Ensembl:ENSMUSG00000066896 +18316 Olfr19 MGI:MGI:109316|Ensembl:ENSMUSG00000048101|Vega:OTTMUSG00000058689 +18317 Olfr2 MGI:MGI:97432|Ensembl:ENSMUSG00000070417|Vega:OTTMUSG00000059731 +18321 Olfr23 MGI:MGI:109312|Ensembl:ENSMUSG00000069816|Vega:OTTMUSG00000006157 +18322 Olfr24 MGI:MGI:109311|Ensembl:ENSMUSG00000054141|Vega:OTTMUSG00000061147 +18323 Olfr25 MGI:MGI:109310|Ensembl:ENSMUSG00000058270|Vega:OTTMUSG00000062002 +18324 Olfr26 MGI:MGI:109309|Ensembl:ENSMUSG00000047667|Vega:OTTMUSG00000062206 +18326 Olfr28 MGI:MGI:109307 +18328 Olfr3 MGI:MGI:102697|Ensembl:ENSMUSG00000075384|Vega:OTTMUSG00000012213 +18329 Olfr30 MGI:MGI:109305|Ensembl:ENSMUSG00000043314|Vega:OTTMUSG00000005732 +18330 Olfr31 MGI:MGI:109304|Ensembl:ENSMUSG00000072707|Vega:OTTMUSG00000058429 +18331 Olfr32 MGI:MGI:109303|Ensembl:ENSMUSG00000075066|Vega:OTTMUSG00000014225 +18332 Olfr33 MGI:MGI:109302|Ensembl:ENSMUSG00000066273|Vega:OTTMUSG00000060052 +18341 Olfr263 MGI:MGI:3030097|Ensembl:ENSMUSG00000071522|Vega:OTTMUSG00000058289 +18343 Olfr44 MGI:MGI:1333829|Ensembl:ENSMUSG00000062649|Vega:OTTMUSG00000062348 +18344 Olfr45 MGI:MGI:1333826|Ensembl:ENSMUSG00000066122|Vega:OTTMUSG00000060430 +18345 Olfr46 MGI:MGI:1333824|Ensembl:ENSMUSG00000093942|Vega:OTTMUSG00000060467 +18346 Olfr47 MGI:MGI:1333821|Ensembl:ENSMUSG00000061210|Vega:OTTMUSG00000057773 +18347 Olfr48 MGI:MGI:1333765|Ensembl:ENSMUSG00000075072|Vega:OTTMUSG00000014237 +18348 Olfr49 MGI:MGI:1333764|Ensembl:ENSMUSG00000048153|Vega:OTTMUSG00000053874 +18349 Olfr5 MGI:MGI:106685|Ensembl:ENSMUSG00000096228|Vega:OTTMUSG00000060113 +18350 Olfr50 MGI:MGI:1333746|Ensembl:ENSMUSG00000111021|Vega:OTTMUSG00000012235 +18351 Olfr51 MGI:MGI:1333747|Ensembl:ENSMUSG00000060918|Vega:OTTMUSG00000007888 +18352 Olfr52 MGI:MGI:1333748|Ensembl:ENSMUSG00000075199|Vega:OTTMUSG00000013662 +18354 Olfr54 MGI:MGI:1333750|Ensembl:ENSMUSG00000059397|Vega:OTTMUSG00000005593 +18356 Olfr56 MGI:MGI:1333785|Ensembl:ENSMUSG00000040328|Vega:OTTMUSG00000005539 +18357 Olfr57 MGI:MGI:1333808|Ensembl:ENSMUSG00000060205|Vega:OTTMUSG00000056767 +18358 Olfr58 MGI:MGI:1333790|Ensembl:ENSMUSG00000058659 +18359 Olfr59 MGI:MGI:1333755|Ensembl:ENSMUSG00000070374 +18361 Olfr60 MGI:MGI:1333881|Ensembl:ENSMUSG00000060112|Vega:OTTMUSG00000060583 +18362 Olfr61 MGI:MGI:1333885|Ensembl:ENSMUSG00000096069|Vega:OTTMUSG00000060468 +18363 Olfr62 MGI:MGI:1333887|Ensembl:ENSMUSG00000043698|Vega:OTTMUSG00000008741 +18365 Olfr65 MGI:MGI:1341910|Ensembl:ENSMUSG00000110259|Vega:OTTMUSG00000019078 +18366 Olfr64 MGI:MGI:1341900|Ensembl:ENSMUSG00000063615|Vega:OTTMUSG00000019194 +18367 Olfr66 MGI:MGI:1341906|Ensembl:ENSMUSG00000058200|Vega:OTTMUSG00000019061 +18368 Olfr67 MGI:MGI:1341911|Ensembl:ENSMUSG00000047535|Vega:OTTMUSG00000019057 +18369 Olfr68 MGI:MGI:1341790|Ensembl:ENSMUSG00000061626|Vega:OTTMUSG00000019101 +18370 Olfr69 MGI:MGI:1341789|Ensembl:ENSMUSG00000058662|Vega:OTTMUSG00000019090 +18371 Olfr7 MGI:MGI:104712 +18372 Olfr8 MGI:MGI:107174|Ensembl:ENSMUSG00000094080|Vega:OTTMUSG00000056727 +18373 Olfr9 MGI:MGI:107600|Ensembl:ENSMUSG00000069430|Vega:OTTMUSG00000056474 +18375 olt MGI:MGI:97433 +18377 Omg MGI:MGI:106586|Ensembl:ENSMUSG00000049612|Vega:OTTMUSG00000000194 +18378 Omp MGI:MGI:97436|Ensembl:ENSMUSG00000074006|Vega:OTTMUSG00000022533 +18379 Omt2a MGI:MGI:106620|Ensembl:ENSMUSG00000066463|Vega:OTTMUSG00000037975 +18383 Tnfrsf11b MGI:MGI:109587|Ensembl:ENSMUSG00000063727 +18386 Oprd1 MGI:MGI:97438|Ensembl:ENSMUSG00000050511|Vega:OTTMUSG00000010973 +18387 Oprk1 MGI:MGI:97439|Ensembl:ENSMUSG00000025905|Vega:OTTMUSG00000034734 +18389 Oprl1 MGI:MGI:97440|Ensembl:ENSMUSG00000027584|Vega:OTTMUSG00000016806 +18390 Oprm1 MGI:MGI:97441|Ensembl:ENSMUSG00000000766|Vega:OTTMUSG00000023338 +18391 Sigmar1 MGI:MGI:1195268|Ensembl:ENSMUSG00000036078|Vega:OTTMUSG00000006675 +18392 Orc1 MGI:MGI:1328337|Ensembl:ENSMUSG00000028587|Vega:OTTMUSG00000008240 +18393 Orc2 MGI:MGI:1328306|Ensembl:ENSMUSG00000026037|Vega:OTTMUSG00000021969 +18399 Slc22a6 MGI:MGI:892001|Ensembl:ENSMUSG00000024650 +18400 Slc22a18 MGI:MGI:1336884|Ensembl:ENSMUSG00000000154|Vega:OTTMUSG00000025376 +18405 Orm1 MGI:MGI:97443|Ensembl:ENSMUSG00000039196|Vega:OTTMUSG00000000305 +18406 Orm2 MGI:MGI:97444|Ensembl:ENSMUSG00000061540|Vega:OTTMUSG00000000306 +18407 Orm3 MGI:MGI:97445|Ensembl:ENSMUSG00000028359|Vega:OTTMUSG00000000245 +18408 Slc25a15 MGI:MGI:1342274|Ensembl:ENSMUSG00000031482|Vega:OTTMUSG00000060883 +18412 Sqstm1 MGI:MGI:107931|Ensembl:ENSMUSG00000015837|Vega:OTTMUSG00000005574 +18413 Osm MGI:MGI:104749|Ensembl:ENSMUSG00000058755|Vega:OTTMUSG00000005054 +18414 Osmr MGI:MGI:1330819|Ensembl:ENSMUSG00000022146|Vega:OTTMUSG00000040092 +18415 Hspa4l MGI:MGI:107422|Ensembl:ENSMUSG00000025757|Vega:OTTMUSG00000023568 +18416 Otc MGI:MGI:97448|Ensembl:ENSMUSG00000031173|Vega:OTTMUSG00000016913 +18417 Cldn11 MGI:MGI:106925|Ensembl:ENSMUSG00000037625|Vega:OTTMUSG00000022650 +18419 Otog MGI:MGI:1202064|Ensembl:ENSMUSG00000009487|Vega:OTTMUSG00000058656 +18420 Otp MGI:MGI:99835|Ensembl:ENSMUSG00000021685|Vega:OTTMUSG00000037627 +18422 Ott MGI:MGI:107573|Ensembl:ENSMUSG00000094885|Vega:OTTMUSG00000018990 +18423 Otx1 MGI:MGI:97450|Ensembl:ENSMUSG00000005917|Vega:OTTMUSG00000005253 +18424 Otx2 MGI:MGI:97451|Ensembl:ENSMUSG00000021848|Vega:OTTMUSG00000032534 +18425 Oua1 MGI:MGI:97452 +18426 Ovol1 MGI:MGI:1330290|Ensembl:ENSMUSG00000024922 +18429 Oxt MGI:MGI:97453|Ensembl:ENSMUSG00000027301|Vega:OTTMUSG00000015519 +18430 Oxtr MGI:MGI:109147|Ensembl:ENSMUSG00000049112|Vega:OTTMUSG00000056498 +18431 Oca2 MGI:MGI:97454|Ensembl:ENSMUSG00000030450|Vega:OTTMUSG00000025863 +18432 Mybbp1a MGI:MGI:106181|Ensembl:ENSMUSG00000040463|Vega:OTTMUSG00000006110 +18436 P2rx1 MGI:MGI:1098235|Ensembl:ENSMUSG00000020787|Vega:OTTMUSG00000006117 +18438 P2rx4 MGI:MGI:1338859|Ensembl:ENSMUSG00000029470|Vega:OTTMUSG00000021392 +18439 P2rx7 MGI:MGI:1339957|Ensembl:ENSMUSG00000029468|Vega:OTTMUSG00000026740 +18440 P2rx6 MGI:MGI:1337113|Ensembl:ENSMUSG00000022758|Vega:OTTMUSG00000035232 +18441 P2ry1 MGI:MGI:105049|Ensembl:ENSMUSG00000027765|Vega:OTTMUSG00000051935 +18442 P2ry2 MGI:MGI:105107|Ensembl:ENSMUSG00000032860|Vega:OTTMUSG00000060008 +18451 P4ha1 MGI:MGI:97463|Ensembl:ENSMUSG00000019916|Vega:OTTMUSG00000034134 +18452 P4ha2 MGI:MGI:894286|Ensembl:ENSMUSG00000018906|Vega:OTTMUSG00000005665 +18453 P4hb MGI:MGI:97464|Ensembl:ENSMUSG00000025130|Vega:OTTMUSG00000004095 +18457 Bloc1s6 MGI:MGI:1927580|Ensembl:ENSMUSG00000005804|Vega:OTTMUSG00000015683 +18458 Pabpc1 MGI:MGI:1349722|Ensembl:ENSMUSG00000022283|Vega:OTTMUSG00000019779 +18459 Pabpc2 MGI:MGI:1349723|Ensembl:ENSMUSG00000051732|Vega:OTTMUSG00000020288 +18462 pad MGI:MGI:97469 +18472 Pafah1b1 MGI:MGI:109520|Ensembl:ENSMUSG00000020745|Vega:OTTMUSG00000006184 +18473 Pafah1b1-ps1 MGI:MGI:103115 +18475 Pafah1b2 MGI:MGI:108415|Ensembl:ENSMUSG00000003131|Vega:OTTMUSG00000063626 +18476 Pafah1b3 MGI:MGI:108414|Ensembl:ENSMUSG00000005447|Vega:OTTMUSG00000023231 +18477 Prdx1 MGI:MGI:99523|Ensembl:ENSMUSG00000028691|Vega:OTTMUSG00000009533 +18478 Pah MGI:MGI:97473|Ensembl:ENSMUSG00000020051 +18479 Pak1 MGI:MGI:1339975|Ensembl:ENSMUSG00000030774|Vega:OTTMUSG00000021135 +18481 Pak3 MGI:MGI:1339656|Ensembl:ENSMUSG00000031284|Vega:OTTMUSG00000018957 +18483 Palm MGI:MGI:1261814|Ensembl:ENSMUSG00000035863 +18484 Pam MGI:MGI:97475|Ensembl:ENSMUSG00000026335|Vega:OTTMUSG00000034777 +18488 Cntn3 MGI:MGI:99534|Ensembl:ENSMUSG00000030075|Vega:OTTMUSG00000057269 +18489 Reg3b MGI:MGI:97478|Ensembl:ENSMUSG00000071356|Vega:OTTMUSG00000057462 +18491 Pappa MGI:MGI:97479|Ensembl:ENSMUSG00000028370|Vega:OTTMUSG00000000318 +18503 Pax1 MGI:MGI:97485|Ensembl:ENSMUSG00000037034|Vega:OTTMUSG00000015696 +18504 Pax2 MGI:MGI:97486|Ensembl:ENSMUSG00000004231|Vega:OTTMUSG00000037630 +18505 Pax3 MGI:MGI:97487|Ensembl:ENSMUSG00000004872|Vega:OTTMUSG00000037633 +18506 Pax4 MGI:MGI:97488|Ensembl:ENSMUSG00000029706|Vega:OTTMUSG00000035782 +18507 Pax5 MGI:MGI:97489|Ensembl:ENSMUSG00000014030|Vega:OTTMUSG00000006705 +18508 Pax6 MGI:MGI:97490|Ensembl:ENSMUSG00000027168|Vega:OTTMUSG00000015006 +18509 Pax7 MGI:MGI:97491|Ensembl:ENSMUSG00000028736|Vega:OTTMUSG00000010060 +18510 Pax8 MGI:MGI:97492|Ensembl:ENSMUSG00000026976|Vega:OTTMUSG00000011957 +18511 Pax9 MGI:MGI:97493|Ensembl:ENSMUSG00000001497|Vega:OTTMUSG00000023206 +18514 Pbx1 MGI:MGI:97495|Ensembl:ENSMUSG00000052534|Vega:OTTMUSG00000040100 +18515 Pbx2 MGI:MGI:1341793|Ensembl:ENSMUSG00000034673|Vega:OTTMUSG00000037073 +18516 Pbx3 MGI:MGI:97496|Ensembl:ENSMUSG00000038718|Vega:OTTMUSG00000011928 +18517 pc MGI:MGI:97497 +18518 Igbp1 MGI:MGI:1346500|Ensembl:ENSMUSG00000031221|Vega:OTTMUSG00000018243 +18519 Kat2b MGI:MGI:1343094|Ensembl:ENSMUSG00000000708|Vega:OTTMUSG00000035538 +18521 Pcbp2 MGI:MGI:108202|Ensembl:ENSMUSG00000056851 +18526 Pcdh10 MGI:MGI:1338042|Ensembl:ENSMUSG00000049100|Vega:OTTMUSG00000050879 +18530 Pcdh8 MGI:MGI:1306800|Ensembl:ENSMUSG00000036422|Vega:OTTMUSG00000050569 +18534 Pck1 MGI:MGI:97501|Ensembl:ENSMUSG00000027513|Vega:OTTMUSG00000016689 +18536 Pcm1 MGI:MGI:1277958|Ensembl:ENSMUSG00000031592|Vega:OTTMUSG00000031635 +18537 Pcmt1 MGI:MGI:97502|Ensembl:ENSMUSG00000019795|Vega:OTTMUSG00000034975 +18538 Pcna MGI:MGI:97503|Ensembl:ENSMUSG00000027342|Vega:OTTMUSG00000015547 +18539 Pcna-ps1 MGI:MGI:97504 +18540 Pcna-ps2 MGI:MGI:97505 +18541 Pcnt MGI:MGI:102722|Ensembl:ENSMUSG00000001151 +18542 Pcolce MGI:MGI:105099|Ensembl:ENSMUSG00000029718|Vega:OTTMUSG00000021947 +18543 pcp MGI:MGI:97506 +18545 Pcp2 MGI:MGI:97508|Ensembl:ENSMUSG00000004630|Vega:OTTMUSG00000032848 +18546 Pcp4 MGI:MGI:97509|Ensembl:ENSMUSG00000090223|Vega:OTTMUSG00000020445 +18548 Pcsk1 MGI:MGI:97511|Ensembl:ENSMUSG00000021587|Vega:OTTMUSG00000026053 +18549 Pcsk2 MGI:MGI:97512|Ensembl:ENSMUSG00000027419|Vega:OTTMUSG00000003089 +18550 Furin MGI:MGI:97513|Ensembl:ENSMUSG00000030530|Vega:OTTMUSG00000028566 +18551 Pcsk4 MGI:MGI:97514|Ensembl:ENSMUSG00000020131|Vega:OTTMUSG00000000019 +18552 Pcsk5 MGI:MGI:97515|Ensembl:ENSMUSG00000024713 +18553 Pcsk6 MGI:MGI:102897|Ensembl:ENSMUSG00000030513|Vega:OTTMUSG00000042239 +18554 Pcsk7 MGI:MGI:107421|Ensembl:ENSMUSG00000035382|Vega:OTTMUSG00000063569 +18555 Cdk16 MGI:MGI:97516|Ensembl:ENSMUSG00000031065|Vega:OTTMUSG00000017159 +18557 Cdk18 MGI:MGI:97518|Ensembl:ENSMUSG00000026437|Vega:OTTMUSG00000049382 +18559 Pctp MGI:MGI:107375|Ensembl:ENSMUSG00000020553|Vega:OTTMUSG00000001285 +18563 Pcx MGI:MGI:97520|Ensembl:ENSMUSG00000024892 +18566 Pdcd1 MGI:MGI:104879|Ensembl:ENSMUSG00000026285|Vega:OTTMUSG00000048696 +18567 Pdcd2 MGI:MGI:104643|Ensembl:ENSMUSG00000014771|Vega:OTTMUSG00000032972 +18569 Pdcd4 MGI:MGI:107490|Ensembl:ENSMUSG00000024975 +18570 Pdcd6 MGI:MGI:109283|Ensembl:ENSMUSG00000021576 +18571 Pdcd6ip MGI:MGI:1333753|Ensembl:ENSMUSG00000032504|Vega:OTTMUSG00000026168 +18572 Pdcd11 MGI:MGI:1341788|Ensembl:ENSMUSG00000025047 +18573 Pde1a MGI:MGI:1201792|Ensembl:ENSMUSG00000059173|Vega:OTTMUSG00000013315 +18574 Pde1b MGI:MGI:97523|Ensembl:ENSMUSG00000022489 +18575 Pde1c MGI:MGI:108413|Ensembl:ENSMUSG00000004347|Vega:OTTMUSG00000023509 +18576 Pde3b MGI:MGI:1333863|Ensembl:ENSMUSG00000030671|Vega:OTTMUSG00000025593 +18577 Pde4a MGI:MGI:99558|Ensembl:ENSMUSG00000032177|Vega:OTTMUSG00000034143 +18578 Pde4b MGI:MGI:99557|Ensembl:ENSMUSG00000028525|Vega:OTTMUSG00000008053 +18582 Pde6d MGI:MGI:1270843|Ensembl:ENSMUSG00000026239|Vega:OTTMUSG00000021876 +18583 Pde7a MGI:MGI:1202402|Ensembl:ENSMUSG00000069094|Vega:OTTMUSG00000030206 +18584 Pde8a MGI:MGI:1277116|Ensembl:ENSMUSG00000025584|Vega:OTTMUSG00000024583 +18585 Pde9a MGI:MGI:1277179|Ensembl:ENSMUSG00000041119|Vega:OTTMUSG00000033902 +18587 Pde6b MGI:MGI:97525|Ensembl:ENSMUSG00000029491|Vega:OTTMUSG00000026326 +18588 Pde6g MGI:MGI:97526|Ensembl:ENSMUSG00000025386|Vega:OTTMUSG00000004174 +18590 Pdgfa MGI:MGI:97527|Ensembl:ENSMUSG00000025856|Vega:OTTMUSG00000025151 +18591 Pdgfb MGI:MGI:97528|Ensembl:ENSMUSG00000000489 +18595 Pdgfra MGI:MGI:97530|Ensembl:ENSMUSG00000029231|Vega:OTTMUSG00000056081 +18596 Pdgfrb MGI:MGI:97531|Ensembl:ENSMUSG00000024620|Vega:OTTMUSG00000014920 +18597 Pdha1 MGI:MGI:97532|Ensembl:ENSMUSG00000031299|Vega:OTTMUSG00000019453 +18598 Pdha2 MGI:MGI:97533|Ensembl:ENSMUSG00000047674|Vega:OTTMUSG00000053679 +18599 Padi1 MGI:MGI:1338893|Ensembl:ENSMUSG00000025329|Vega:OTTMUSG00000010082 +18600 Padi2 MGI:MGI:1338892|Ensembl:ENSMUSG00000028927|Vega:OTTMUSG00000010085 +18601 Padi3 MGI:MGI:1338891|Ensembl:ENSMUSG00000025328|Vega:OTTMUSG00000010034 +18602 Padi4 MGI:MGI:1338898|Ensembl:ENSMUSG00000025330|Vega:OTTMUSG00000010033 +18604 Pdk2 MGI:MGI:1343087|Ensembl:ENSMUSG00000038967|Vega:OTTMUSG00000001622 +18605 Enpp1 MGI:MGI:97370|Ensembl:ENSMUSG00000037370|Vega:OTTMUSG00000019714 +18606 Enpp2 MGI:MGI:1321390|Ensembl:ENSMUSG00000022425|Vega:OTTMUSG00000037584 +18607 Pdpk1 MGI:MGI:1338068|Ensembl:ENSMUSG00000024122|Vega:OTTMUSG00000016280 +18608 pdw MGI:MGI:99399 +18609 Pdx1 MGI:MGI:102851|Ensembl:ENSMUSG00000029644|Vega:OTTMUSG00000037552 +18610 Pdyn MGI:MGI:97535|Ensembl:ENSMUSG00000027400|Vega:OTTMUSG00000015494 +18611 Pea15a MGI:MGI:104799|Ensembl:ENSMUSG00000013698|Vega:OTTMUSG00000022139 +18612 Etv4 MGI:MGI:99423|Ensembl:ENSMUSG00000017724|Vega:OTTMUSG00000002089 +18613 Pecam1 MGI:MGI:97537|Ensembl:ENSMUSG00000020717|Vega:OTTMUSG00000003418 +18616 Peg3 MGI:MGI:104748|Ensembl:ENSMUSG00000002265|Vega:OTTMUSG00000022283 +18617 Rhox5 MGI:MGI:97538|Ensembl:ENSMUSG00000095180|Vega:OTTMUSG00000044441 +18618 Pemt MGI:MGI:104535|Ensembl:ENSMUSG00000000301|Vega:OTTMUSG00000005808 +18619 Penk MGI:MGI:104629|Ensembl:ENSMUSG00000045573|Vega:OTTMUSG00000004406 +18624 Pepd MGI:MGI:97542|Ensembl:ENSMUSG00000063931|Vega:OTTMUSG00000031826 +18626 Per1 MGI:MGI:1098283|Ensembl:ENSMUSG00000020893|Vega:OTTMUSG00000005970 +18627 Per2 MGI:MGI:1195265|Ensembl:ENSMUSG00000055866|Vega:OTTMUSG00000048493 +18628 Per3 MGI:MGI:1277134|Ensembl:ENSMUSG00000028957|Vega:OTTMUSG00000010238 +18630 Pet2 MGI:MGI:101758|Ensembl:ENSMUSG00000035395|Vega:OTTMUSG00000018051 +18631 Pex11a MGI:MGI:1338788|Ensembl:ENSMUSG00000030545|Vega:OTTMUSG00000024967 +18632 Pex11b MGI:MGI:1338882|Ensembl:ENSMUSG00000028102|Vega:OTTMUSG00000029574 +18633 Pex16 MGI:MGI:1338829|Ensembl:ENSMUSG00000027222|Vega:OTTMUSG00000014473 +18634 Pex7 MGI:MGI:1321392|Ensembl:ENSMUSG00000020003|Vega:OTTMUSG00000031072 +18635 pf MGI:MGI:97544 +18636 Cfp MGI:MGI:97545|Ensembl:ENSMUSG00000001128|Vega:OTTMUSG00000017182 +18637 Pfdn2 MGI:MGI:1276111|Ensembl:ENSMUSG00000006412|Vega:OTTMUSG00000021718 +18639 Pfkfb1 MGI:MGI:107816|Ensembl:ENSMUSG00000025271|Vega:OTTMUSG00000019170 +18640 Pfkfb2 MGI:MGI:107815|Ensembl:ENSMUSG00000026409|Vega:OTTMUSG00000049608 +18641 Pfkl MGI:MGI:97547|Ensembl:ENSMUSG00000020277|Vega:OTTMUSG00000016976 +18642 Pfkm MGI:MGI:97548|Ensembl:ENSMUSG00000033065 +18643 Pfn1 MGI:MGI:97549|Ensembl:ENSMUSG00000018293|Vega:OTTMUSG00000006068 +18645 Pfn2 MGI:MGI:97550|Ensembl:ENSMUSG00000027805|Vega:OTTMUSG00000026672 +18646 Prf1 MGI:MGI:97551|Ensembl:ENSMUSG00000037202 +18647 Cdk14 MGI:MGI:894318|Ensembl:ENSMUSG00000028926|Vega:OTTMUSG00000023486 +18648 Pgam1 MGI:MGI:97552|Ensembl:ENSMUSG00000011752 +18654 Pgf MGI:MGI:105095|Ensembl:ENSMUSG00000004791 +18655 Pgk1 MGI:MGI:97555|Ensembl:ENSMUSG00000062070|Vega:OTTMUSG00000018277 +18656 Pgk1-ps1 MGI:MGI:97556 +18663 Pgk2 MGI:MGI:97563|Ensembl:ENSMUSG00000031233 +18667 Pgr MGI:MGI:97567|Ensembl:ENSMUSG00000031870|Vega:OTTMUSG00000022998 +18669 Abcb1b MGI:MGI:97568|Ensembl:ENSMUSG00000028970|Vega:OTTMUSG00000054347 +18670 Abcb4 MGI:MGI:97569|Ensembl:ENSMUSG00000042476|Vega:OTTMUSG00000054368 +18671 Abcb1a MGI:MGI:97570|Ensembl:ENSMUSG00000040584|Vega:OTTMUSG00000029053 +18673 Phb MGI:MGI:97572|Ensembl:ENSMUSG00000038845|Vega:OTTMUSG00000001749 +18674 Slc25a3 MGI:MGI:1353498|Ensembl:ENSMUSG00000061904|Vega:OTTMUSG00000035180 +18675 Phex MGI:MGI:107489|Ensembl:ENSMUSG00000057457 +18676 Phf2 MGI:MGI:1338034|Ensembl:ENSMUSG00000038025 +18679 Phka1 MGI:MGI:97576|Ensembl:ENSMUSG00000034055|Vega:OTTMUSG00000018059 +18682 Phkg1 MGI:MGI:97579|Ensembl:ENSMUSG00000025537|Vega:OTTMUSG00000023980 +18685 Phtf1 MGI:MGI:1332671|Ensembl:ENSMUSG00000058388|Vega:OTTMUSG00000024266 +18686 Phxr1 MGI:MGI:104525 +18687 Phxr2 MGI:MGI:104524 +18689 Phxr4 MGI:MGI:104522|Ensembl:ENSMUSG00000031802 +18690 Phxr5 MGI:MGI:104521 +18693 Pick1 MGI:MGI:894645|Ensembl:ENSMUSG00000068206|Vega:OTTMUSG00000036025 +18698 pid MGI:MGI:102560 +18700 Piga MGI:MGI:99461|Ensembl:ENSMUSG00000031381|Vega:OTTMUSG00000019508 +18701 Pigf MGI:MGI:99462|Ensembl:ENSMUSG00000024145|Vega:OTTMUSG00000024353 +18703 Pigr MGI:MGI:103080|Ensembl:ENSMUSG00000026417|Vega:OTTMUSG00000022632 +18704 Pik3c2a MGI:MGI:1203729|Ensembl:ENSMUSG00000030660|Vega:OTTMUSG00000058790 +18705 Pik3c2g MGI:MGI:1203730|Ensembl:ENSMUSG00000030228 +18706 Pik3ca MGI:MGI:1206581|Ensembl:ENSMUSG00000027665|Vega:OTTMUSG00000021191 +18707 Pik3cd MGI:MGI:1098211|Ensembl:ENSMUSG00000039936|Vega:OTTMUSG00000010264 +18708 Pik3r1 MGI:MGI:97583|Ensembl:ENSMUSG00000041417|Vega:OTTMUSG00000048150 +18709 Pik3r2 MGI:MGI:1098772|Ensembl:ENSMUSG00000031834|Vega:OTTMUSG00000032469 +18710 Pik3r3 MGI:MGI:109277|Ensembl:ENSMUSG00000028698|Ensembl:ENSMUSG00000111410|Vega:OTTMUSG00000009411|Vega:OTTMUSG00000062946 +18711 Pikfyve MGI:MGI:1335106|Ensembl:ENSMUSG00000025949|Vega:OTTMUSG00000047694 +18712 Pim1 MGI:MGI:97584|Ensembl:ENSMUSG00000024014|Vega:OTTMUSG00000046297 +18715 Pim2 MGI:MGI:97587|Ensembl:ENSMUSG00000031155|Vega:OTTMUSG00000018000 +18716 Pip MGI:MGI:102696|Ensembl:ENSMUSG00000058499|Vega:OTTMUSG00000057831 +18717 Pip5k1c MGI:MGI:1298224|Ensembl:ENSMUSG00000034902|Vega:OTTMUSG00000033475 +18718 Pip4k2a MGI:MGI:1298206|Ensembl:ENSMUSG00000026737|Vega:OTTMUSG00000011477 +18719 Pip5k1b MGI:MGI:107930|Ensembl:ENSMUSG00000024867|Vega:OTTMUSG00000031802 +18720 Pip5k1a MGI:MGI:107929|Ensembl:ENSMUSG00000028126|Vega:OTTMUSG00000019671 +18722 Pira1 MGI:MGI:1195971|Ensembl:ENSMUSG00000081665|Vega:OTTMUSG00000027884 +18724 Pira11 MGI:MGI:1276541 +18725 Pira2 MGI:MGI:1195970|Ensembl:ENSMUSG00000089942|Vega:OTTMUSG00000027892 +18726 Lilra6 MGI:MGI:1195969|Ensembl:ENSMUSG00000030427|Vega:OTTMUSG00000021305 +18727 Pira4 MGI:MGI:1195988 +18728 Pira5 MGI:MGI:1195975 +18729 Pira6 MGI:MGI:1195974 +18730 Pira7 MGI:MGI:1195973 +18733 Pirb MGI:MGI:894311|Ensembl:ENSMUSG00000058818|Vega:OTTMUSG00000020499 +18736 Pou1f1 MGI:MGI:97588|Ensembl:ENSMUSG00000004842|Vega:OTTMUSG00000039845 +18738 Pitpna MGI:MGI:99887|Ensembl:ENSMUSG00000017781|Vega:OTTMUSG00000006217 +18739 Pitpnm1 MGI:MGI:1197524|Ensembl:ENSMUSG00000024851|Vega:OTTMUSG00000026157 +18740 Pitx1 MGI:MGI:107374|Ensembl:ENSMUSG00000021506|Vega:OTTMUSG00000037718 +18741 Pitx2 MGI:MGI:109340|Ensembl:ENSMUSG00000028023|Vega:OTTMUSG00000037721 +18742 Pitx3 MGI:MGI:1100498|Ensembl:ENSMUSG00000025229|Vega:OTTMUSG00000021234 +18744 Pja1 MGI:MGI:1101765|Ensembl:ENSMUSG00000034403|Vega:OTTMUSG00000018068 +18745 pk MGI:MGI:97590 +18746 Pkm MGI:MGI:97591|Ensembl:ENSMUSG00000032294|Vega:OTTMUSG00000063298 +18747 Prkaca MGI:MGI:97592|Ensembl:ENSMUSG00000005469|Vega:OTTMUSG00000061189 +18749 Prkacb MGI:MGI:97594|Ensembl:ENSMUSG00000005034|Vega:OTTMUSG00000016475 +18750 Prkca MGI:MGI:97595|Ensembl:ENSMUSG00000050965|Vega:OTTMUSG00000003131 +18751 Prkcb MGI:MGI:97596|Ensembl:ENSMUSG00000052889|Vega:OTTMUSG00000016521 +18752 Prkcg MGI:MGI:97597|Ensembl:ENSMUSG00000078816|Vega:OTTMUSG00000057714 +18753 Prkcd MGI:MGI:97598|Ensembl:ENSMUSG00000021948|Vega:OTTMUSG00000025129 +18754 Prkce MGI:MGI:97599|Ensembl:ENSMUSG00000045038|Vega:OTTMUSG00000017512 +18755 Prkch MGI:MGI:97600|Ensembl:ENSMUSG00000021108|Vega:OTTMUSG00000029341 +18759 Prkci MGI:MGI:99260|Ensembl:ENSMUSG00000037643|Vega:OTTMUSG00000032732 +18760 Prkd1 MGI:MGI:99879|Ensembl:ENSMUSG00000002688 +18761 Prkcq MGI:MGI:97601|Ensembl:ENSMUSG00000026778|Vega:OTTMUSG00000011317 +18762 Prkcz MGI:MGI:97602|Ensembl:ENSMUSG00000029053|Vega:OTTMUSG00000010601 +18763 Pkd1 MGI:MGI:97603|Ensembl:ENSMUSG00000032855 +18764 Pkd2 MGI:MGI:1099818|Ensembl:ENSMUSG00000034462|Vega:OTTMUSG00000025951 +18766 Pkdrej MGI:MGI:1338786|Ensembl:ENSMUSG00000052496 +18767 Pkia MGI:MGI:104747|Ensembl:ENSMUSG00000027499|Vega:OTTMUSG00000051305 +18768 Pkib MGI:MGI:101937|Ensembl:ENSMUSG00000019876|Vega:OTTMUSG00000042041 +18769 Pkig MGI:MGI:1343086|Ensembl:ENSMUSG00000035268|Vega:OTTMUSG00000001148 +18770 Pklr MGI:MGI:97604|Ensembl:ENSMUSG00000041237|Vega:OTTMUSG00000017504 +18771 Pknox1 MGI:MGI:1201409|Ensembl:ENSMUSG00000006705|Vega:OTTMUSG00000040106 +18772 Pkp1 MGI:MGI:1328359|Ensembl:ENSMUSG00000026413|Vega:OTTMUSG00000022498 +18774 pl MGI:MGI:97605 +18775 Prl3d1 MGI:MGI:97606|Ensembl:ENSMUSG00000057170|Vega:OTTMUSG00000000627 +18776 Prl3b1 MGI:MGI:97607|Ensembl:ENSMUSG00000038891|Vega:OTTMUSG00000000628 +18777 Lypla1 MGI:MGI:1344588|Ensembl:ENSMUSG00000025903|Vega:OTTMUSG00000021562 +18778 Pla2g1b MGI:MGI:101842|Ensembl:ENSMUSG00000029522|Vega:OTTMUSG00000014666 +18779 Pla2r1 MGI:MGI:102468|Ensembl:ENSMUSG00000054580|Vega:OTTMUSG00000012715 +18780 Pla2g2a MGI:MGI:104642|Ensembl:ENSMUSG00000058908|Vega:OTTMUSG00000010068 +18781 Pla2g2c MGI:MGI:106638|Ensembl:ENSMUSG00000028750|Vega:OTTMUSG00000010007 +18782 Pla2g2d MGI:MGI:1341796|Ensembl:ENSMUSG00000041202|Vega:OTTMUSG00000010029 +18783 Pla2g4a MGI:MGI:1195256|Ensembl:ENSMUSG00000056220|Vega:OTTMUSG00000016429 +18784 Pla2g5 MGI:MGI:101899|Ensembl:ENSMUSG00000041193|Vega:OTTMUSG00000010028 +18786 Plaa MGI:MGI:104810|Ensembl:ENSMUSG00000028577|Vega:OTTMUSG00000007850 +18787 Serpine1 MGI:MGI:97608|Ensembl:ENSMUSG00000037411|Vega:OTTMUSG00000054456 +18788 Serpinb2 MGI:MGI:97609|Ensembl:ENSMUSG00000062345|Vega:OTTMUSG00000021001 +18789 Papola MGI:MGI:109301|Ensembl:ENSMUSG00000021111|Vega:OTTMUSG00000035482 +18791 Plat MGI:MGI:97610|Ensembl:ENSMUSG00000031538|Vega:OTTMUSG00000060895 +18792 Plau MGI:MGI:97611|Ensembl:ENSMUSG00000021822 +18793 Plaur MGI:MGI:97612|Ensembl:ENSMUSG00000046223|Vega:OTTMUSG00000058079 +18795 Plcb1 MGI:MGI:97613|Ensembl:ENSMUSG00000051177|Vega:OTTMUSG00000015592 +18796 Plcb2 MGI:MGI:107465|Ensembl:ENSMUSG00000040061|Vega:OTTMUSG00000015372 +18797 Plcb3 MGI:MGI:104778|Ensembl:ENSMUSG00000024960 +18798 Plcb4 MGI:MGI:107464|Ensembl:ENSMUSG00000039943|Vega:OTTMUSG00000015959 +18799 Plcd1 MGI:MGI:97614|Ensembl:ENSMUSG00000010660|Vega:OTTMUSG00000062974 +18802 Plcd4 MGI:MGI:107469|Ensembl:ENSMUSG00000026173|Vega:OTTMUSG00000021578 +18803 Plcg1 MGI:MGI:97615|Ensembl:ENSMUSG00000016933|Vega:OTTMUSG00000001177 +18805 Pld1 MGI:MGI:109585|Ensembl:ENSMUSG00000027695|Vega:OTTMUSG00000028207 +18806 Pld2 MGI:MGI:892877|Ensembl:ENSMUSG00000020828|Vega:OTTMUSG00000006051 +18807 Pld3 MGI:MGI:1333782|Ensembl:ENSMUSG00000003363|Vega:OTTMUSG00000031815 +18809 ple MGI:MGI:97617 +18810 Plec MGI:MGI:1277961|Ensembl:ENSMUSG00000022565|Vega:OTTMUSG00000035240 +18811 Prl2c2 MGI:MGI:97618|Ensembl:ENSMUSG00000079092 +18812 Prl2c3 MGI:MGI:1341833|Ensembl:ENSMUSG00000056457 +18813 Pa2g4 MGI:MGI:894684|Ensembl:ENSMUSG00000025364|Vega:OTTMUSG00000024830 +18814 Prl7d1 MGI:MGI:97619|Ensembl:ENSMUSG00000021348|Vega:OTTMUSG00000000648 +18815 Plg MGI:MGI:97620|Ensembl:ENSMUSG00000059481 +18816 Serpinf2 MGI:MGI:107173|Ensembl:ENSMUSG00000038224|Vega:OTTMUSG00000006204 +18817 Plk1 MGI:MGI:97621|Ensembl:ENSMUSG00000030867|Vega:OTTMUSG00000058103 +18818 Plk-ps1 MGI:MGI:103247 +18821 Pln MGI:MGI:97622|Ensembl:ENSMUSG00000038583 +18822 Plod1 MGI:MGI:99907|Ensembl:ENSMUSG00000019055|Vega:OTTMUSG00000010675 +18823 Plp1 MGI:MGI:97623|Ensembl:ENSMUSG00000031425|Vega:OTTMUSG00000016519 +18824 Plp2 MGI:MGI:1298382|Ensembl:ENSMUSG00000031146|Vega:OTTMUSG00000017753 +18826 Lcp1 MGI:MGI:104808|Ensembl:ENSMUSG00000021998|Vega:OTTMUSG00000024579 +18828 Plscr2 MGI:MGI:1270860|Ensembl:ENSMUSG00000032372|Vega:OTTMUSG00000022967 +18829 Ccl21a MGI:MGI:1349183|Ensembl:ENSMUSG00000094686|Vega:OTTMUSG00000006590 +18830 Pltp MGI:MGI:103151|Ensembl:ENSMUSG00000017754|Vega:OTTMUSG00000001168 +18843 Bpifa1 MGI:MGI:1338036|Ensembl:ENSMUSG00000027483|Vega:OTTMUSG00000016850 +18844 Plxna1 MGI:MGI:107685|Ensembl:ENSMUSG00000030084|Vega:OTTMUSG00000057675 +18845 Plxna2 MGI:MGI:107684|Ensembl:ENSMUSG00000026640|Vega:OTTMUSG00000017321 +18846 Plxna3 MGI:MGI:107683|Ensembl:ENSMUSG00000031398|Vega:OTTMUSG00000017689 +18849 pma MGI:MGI:97628 +18854 Pml MGI:MGI:104662|Ensembl:ENSMUSG00000036986|Vega:OTTMUSG00000033332 +18857 Pmp2 MGI:MGI:102667|Ensembl:ENSMUSG00000052468|Vega:OTTMUSG00000051460 +18858 Pmp22 MGI:MGI:97631|Ensembl:ENSMUSG00000018217|Vega:OTTMUSG00000005884 +18861 Pms2 MGI:MGI:104288|Ensembl:ENSMUSG00000075569|Ensembl:ENSMUSG00000079109|Vega:OTTMUSG00000035941|Vega:OTTMUSG00000054938 +18933 Prrx1 MGI:MGI:97712|Ensembl:ENSMUSG00000026586|Vega:OTTMUSG00000037738 +18935 Phox2b MGI:MGI:1100882|Ensembl:ENSMUSG00000012520|Vega:OTTMUSG00000037720 +18936 pn MGI:MGI:97714 +18938 Ppp1r14b MGI:MGI:107682|Ensembl:ENSMUSG00000056612 +18939 Pnlf1 MGI:MGI:97716 +18940 Pnlf2 MGI:MGI:97717 +18941 Pnlf3 MGI:MGI:97718 +18942 Pnlf4 MGI:MGI:97719 +18943 Pnlf5 MGI:MGI:97720 +18944 Pnlf6 MGI:MGI:97721 +18946 Pnliprp1 MGI:MGI:97723|Ensembl:ENSMUSG00000042179 +18947 Pnliprp2 MGI:MGI:1336202|Ensembl:ENSMUSG00000025091 +18948 Pnmt MGI:MGI:97724|Ensembl:ENSMUSG00000038216|Vega:OTTMUSG00000002714 +18949 Pnn MGI:MGI:1100514|Ensembl:ENSMUSG00000020994 +18950 Pnp MGI:MGI:97365|Ensembl:ENSMUSG00000021871|Vega:OTTMUSG00000032495 +18951 Sept5 MGI:MGI:1195461|Ensembl:ENSMUSG00000072214 +18952 Sept4 MGI:MGI:1270156|Ensembl:ENSMUSG00000020486|Vega:OTTMUSG00000001264 +18968 Pola1 MGI:MGI:99660|Ensembl:ENSMUSG00000006678|Vega:OTTMUSG00000017971 +18969 Pola2 MGI:MGI:99690|Ensembl:ENSMUSG00000024833 +18970 Polb MGI:MGI:97740|Ensembl:ENSMUSG00000031536|Vega:OTTMUSG00000060893 +18971 Pold1 MGI:MGI:97741|Ensembl:ENSMUSG00000038644|Vega:OTTMUSG00000028995 +18972 Pold2 MGI:MGI:1097163|Ensembl:ENSMUSG00000020471|Vega:OTTMUSG00000005094 +18973 Pole MGI:MGI:1196391|Ensembl:ENSMUSG00000007080|Vega:OTTMUSG00000026219 +18974 Pole2 MGI:MGI:1197514|Ensembl:ENSMUSG00000020974 +18975 Polg MGI:MGI:1196389|Ensembl:ENSMUSG00000039176|Vega:OTTMUSG00000029097 +18976 Pomc MGI:MGI:97742|Ensembl:ENSMUSG00000020660 +18977 Pomc-ps1 MGI:MGI:104962 +18979 Pon1 MGI:MGI:103295|Ensembl:ENSMUSG00000002588|Vega:OTTMUSG00000042263 +18983 Cnot7 MGI:MGI:1298230|Ensembl:ENSMUSG00000031601|Vega:OTTMUSG00000026076 +18984 Por MGI:MGI:97744|Ensembl:ENSMUSG00000005514|Vega:OTTMUSG00000029621 +18985 Pou2af1 MGI:MGI:105086|Ensembl:ENSMUSG00000032053|Vega:OTTMUSG00000063080 +18986 Pou2f1 MGI:MGI:101898|Ensembl:ENSMUSG00000026565|Vega:OTTMUSG00000034833 +18987 Pou2f2 MGI:MGI:101897|Ensembl:ENSMUSG00000008496|Vega:OTTMUSG00000020444 +18988 Pou2f3 MGI:MGI:102565|Ensembl:ENSMUSG00000032015|Vega:OTTMUSG00000039872 +18990 Pou3f-rs1 MGI:MGI:102577 +18991 Pou3f1 MGI:MGI:101896|Ensembl:ENSMUSG00000090125|Vega:OTTMUSG00000042459 +18992 Pou3f2 MGI:MGI:101895|Ensembl:ENSMUSG00000095139|Vega:OTTMUSG00000004749 +18993 Pou3f3 MGI:MGI:102564|Ensembl:ENSMUSG00000045515|Vega:OTTMUSG00000022569 +18994 Pou3f4 MGI:MGI:101894|Ensembl:ENSMUSG00000056854|Vega:OTTMUSG00000018379 +18996 Pou4f1 MGI:MGI:102525|Ensembl:ENSMUSG00000048349|Vega:OTTMUSG00000032816 +18997 Pou4f2 MGI:MGI:102524|Ensembl:ENSMUSG00000031688|Vega:OTTMUSG00000039883 +18998 Pou4f3 MGI:MGI:102523|Ensembl:ENSMUSG00000024497|Vega:OTTMUSG00000039884 +18999 Pou5f1 MGI:MGI:101893|Ensembl:ENSMUSG00000024406|Vega:OTTMUSG00000037235 +19009 Pou6f1 MGI:MGI:102935|Ensembl:ENSMUSG00000009739|Vega:OTTMUSG00000039916 +19011 Endou MGI:MGI:97746|Ensembl:ENSMUSG00000022468 +19012 Plpp1 MGI:MGI:108412|Ensembl:ENSMUSG00000021759 +19013 Ppara MGI:MGI:104740|Ensembl:ENSMUSG00000022383|Vega:OTTMUSG00000023590 +19014 Med1 MGI:MGI:1100846|Ensembl:ENSMUSG00000018160|Vega:OTTMUSG00000002636 +19015 Ppard MGI:MGI:101884|Ensembl:ENSMUSG00000002250|Vega:OTTMUSG00000023384 +19016 Pparg MGI:MGI:97747|Ensembl:ENSMUSG00000000440|Vega:OTTMUSG00000056643 +19017 Ppargc1a MGI:MGI:1342774|Ensembl:ENSMUSG00000029167|Vega:OTTMUSG00000022759 +19018 Scand1 MGI:MGI:1343132|Ensembl:ENSMUSG00000046229 +19023 Ppef2 MGI:MGI:1342304|Ensembl:ENSMUSG00000029410|Vega:OTTMUSG00000055589 +19024 Ppfibp2 MGI:MGI:894649|Ensembl:ENSMUSG00000036528|Vega:OTTMUSG00000059746 +19025 Ctsa MGI:MGI:97748|Ensembl:ENSMUSG00000017760|Vega:OTTMUSG00000001170 +19027 Sypl MGI:MGI:108081|Ensembl:ENSMUSG00000020570|Vega:OTTMUSG00000027537 +19034 Gm10123 MGI:MGI:3704342 +19035 Ppib MGI:MGI:97750|Ensembl:ENSMUSG00000032383|Vega:OTTMUSG00000062641 +19038 Ppic MGI:MGI:97751|Ensembl:ENSMUSG00000024538 +19039 Lgals3bp MGI:MGI:99554|Ensembl:ENSMUSG00000033880|Vega:OTTMUSG00000003881 +19041 Ppl MGI:MGI:1194898|Ensembl:ENSMUSG00000039457 +19042 Ppm1a MGI:MGI:99878|Ensembl:ENSMUSG00000021096 +19043 Ppm1b MGI:MGI:101841|Ensembl:ENSMUSG00000061130 +19044 Ppox MGI:MGI:104968|Ensembl:ENSMUSG00000062729|Vega:OTTMUSG00000021555 +19045 Ppp1ca MGI:MGI:103016|Ensembl:ENSMUSG00000040385 +19046 Ppp1cb MGI:MGI:104871|Ensembl:ENSMUSG00000014956|Vega:OTTMUSG00000024328 +19047 Ppp1cc MGI:MGI:104872|Ensembl:ENSMUSG00000004455|Vega:OTTMUSG00000016349 +19049 Ppp1r1b MGI:MGI:94860|Ensembl:ENSMUSG00000061718|Vega:OTTMUSG00000002634 +19051 Ppp1r17 MGI:MGI:1333876|Ensembl:ENSMUSG00000002930|Vega:OTTMUSG00000057891 +19052 Ppp2ca MGI:MGI:1321159|Ensembl:ENSMUSG00000020349|Vega:OTTMUSG00000005619 +19053 Ppp2cb MGI:MGI:1321161|Ensembl:ENSMUSG00000009630|Vega:OTTMUSG00000060960 +19054 Ppp2r3d MGI:MGI:1335093|Ensembl:ENSMUSG00000093803|Vega:OTTMUSG00000046326 +19055 Ppp3ca MGI:MGI:107164|Ensembl:ENSMUSG00000028161|Vega:OTTMUSG00000016446 +19056 Ppp3cb MGI:MGI:107163|Ensembl:ENSMUSG00000021816|Vega:OTTMUSG00000034313 +19057 Ppp3cc MGI:MGI:107162|Ensembl:ENSMUSG00000022092 +19058 Ppp3r1 MGI:MGI:107172|Ensembl:ENSMUSG00000033953|Vega:OTTMUSG00000005195 +19059 Ppp3r2 MGI:MGI:107171|Ensembl:ENSMUSG00000028310|Vega:OTTMUSG00000006951 +19060 Ppp5c MGI:MGI:102666|Ensembl:ENSMUSG00000003099|Vega:OTTMUSG00000016479 +19062 Inpp5k MGI:MGI:1194899|Ensembl:ENSMUSG00000006127|Vega:OTTMUSG00000006214 +19063 Ppt1 MGI:MGI:1298204|Ensembl:ENSMUSG00000028657|Vega:OTTMUSG00000008871 +19064 Ppy MGI:MGI:97753|Ensembl:ENSMUSG00000017316|Vega:OTTMUSG00000002317 +19065 Npy4r MGI:MGI:105374|Ensembl:ENSMUSG00000048337 +19066 pr MGI:MGI:97754 +19069 Nup88 MGI:MGI:104900|Ensembl:ENSMUSG00000040667|Vega:OTTMUSG00000006081 +19070 Mob4 MGI:MGI:104899|Ensembl:ENSMUSG00000025979|Vega:OTTMUSG00000034749 +19072 Prep MGI:MGI:1270863|Ensembl:ENSMUSG00000019849|Vega:OTTMUSG00000063711 +19073 Srgn MGI:MGI:97756|Ensembl:ENSMUSG00000020077|Vega:OTTMUSG00000024719 +19074 Prg2 MGI:MGI:103294|Ensembl:ENSMUSG00000027073|Vega:OTTMUSG00000013454 +19075 Prim1 MGI:MGI:97757|Ensembl:ENSMUSG00000025395|Vega:OTTMUSG00000033813 +19076 Prim2 MGI:MGI:97758|Ensembl:ENSMUSG00000026134|Vega:OTTMUSG00000049047 +19079 Prkab1 MGI:MGI:1336167|Ensembl:ENSMUSG00000029513|Vega:OTTMUSG00000014718 +19082 Prkag1 MGI:MGI:108411|Ensembl:ENSMUSG00000067713 +19084 Prkar1a MGI:MGI:104878|Ensembl:ENSMUSG00000020612|Vega:OTTMUSG00000003351 +19085 Prkar1b MGI:MGI:97759|Ensembl:ENSMUSG00000025855|Vega:OTTMUSG00000025121 +19086 Prkar1b-rs MGI:MGI:107805 +19087 Prkar2a MGI:MGI:108025|Ensembl:ENSMUSG00000032601|Vega:OTTMUSG00000050671 +19088 Prkar2b MGI:MGI:97760|Ensembl:ENSMUSG00000002997|Vega:OTTMUSG00000016980 +19089 Prkcsh MGI:MGI:107877|Ensembl:ENSMUSG00000003402|Vega:OTTMUSG00000062326 +19090 Prkdc MGI:MGI:104779|Ensembl:ENSMUSG00000022672|Vega:OTTMUSG00000043440 +19091 Prkg1 MGI:MGI:108174|Ensembl:ENSMUSG00000052920|Vega:OTTMUSG00000043089 +19092 Prkg2 MGI:MGI:108173|Ensembl:ENSMUSG00000029334|Vega:OTTMUSG00000033394 +19094 Mapk11 MGI:MGI:1338024|Ensembl:ENSMUSG00000053137 +19099 Mapk8ip1 MGI:MGI:1309464|Ensembl:ENSMUSG00000027223|Vega:OTTMUSG00000014470 +19106 Eif2ak2 MGI:MGI:1353449|Ensembl:ENSMUSG00000024079|Vega:OTTMUSG00000036019 +19108 Prkx MGI:MGI:1309999|Ensembl:ENSMUSG00000035725|Vega:OTTMUSG00000017860 +19109 Prl MGI:MGI:97762|Ensembl:ENSMUSG00000021342|Vega:OTTMUSG00000000731 +19110 Prl4a1 MGI:MGI:1206587|Ensembl:ENSMUSG00000005891|Vega:OTTMUSG00000000653 +19111 Prl6a1 MGI:MGI:1206579|Ensembl:ENSMUSG00000069259|Vega:OTTMUSG00000000636 +19112 Prl8a6 MGI:MGI:1332225|Ensembl:ENSMUSG00000021345|Vega:OTTMUSG00000000635 +19113 Prl7a1 MGI:MGI:1206572|Ensembl:ENSMUSG00000006488|Vega:OTTMUSG00000000642 +19114 Prl7a2 MGI:MGI:1206571|Ensembl:ENSMUSG00000046899|Vega:OTTMUSG00000000643 +19116 Prlr MGI:MGI:97763|Ensembl:ENSMUSG00000005268|Vega:OTTMUSG00000023932 +19118 Prm1 MGI:MGI:97765|Ensembl:ENSMUSG00000022501|Vega:OTTMUSG00000025621 +19119 Prm2 MGI:MGI:97766|Ensembl:ENSMUSG00000038015|Vega:OTTMUSG00000048599 +19120 Prm3 MGI:MGI:106601|Ensembl:ENSMUSG00000050058|Vega:OTTMUSG00000048601 +19122 Prnp MGI:MGI:97769|Ensembl:ENSMUSG00000079037|Vega:OTTMUSG00000014846 +19123 Proc MGI:MGI:97771|Ensembl:ENSMUSG00000024386 +19124 Procr MGI:MGI:104596|Ensembl:ENSMUSG00000027611|Vega:OTTMUSG00000016132 +19125 Prodh MGI:MGI:97770|Ensembl:ENSMUSG00000003526|Vega:OTTMUSG00000028177 +19126 Prom1 MGI:MGI:1100886|Ensembl:ENSMUSG00000029086|Vega:OTTMUSG00000053805 +19127 Prop1 MGI:MGI:109330|Ensembl:ENSMUSG00000044542|Vega:OTTMUSG00000007884 +19128 Pros1 MGI:MGI:1095733|Ensembl:ENSMUSG00000022912|Vega:OTTMUSG00000027260 +19130 Prox1 MGI:MGI:97772|Ensembl:ENSMUSG00000010175|Vega:OTTMUSG00000040162 +19131 Prh1 MGI:MGI:97773|Ensembl:ENSMUSG00000059934|Vega:OTTMUSG00000039811 +19132 Prph MGI:MGI:97774|Ensembl:ENSMUSG00000023484 +19133 Prph2 MGI:MGI:102791|Ensembl:ENSMUSG00000023978|Vega:OTTMUSG00000034269 +19134 Prpf4b MGI:MGI:109584|Ensembl:ENSMUSG00000021413 +19139 Prps1 MGI:MGI:97775|Ensembl:ENSMUSG00000031432|Vega:OTTMUSG00000018847 +19141 Lgmn MGI:MGI:1330838|Ensembl:ENSMUSG00000021190|Vega:OTTMUSG00000023302 +19142 Prss12 MGI:MGI:1100881|Ensembl:ENSMUSG00000027978|Vega:OTTMUSG00000052551 +19143 St14 MGI:MGI:1338881|Ensembl:ENSMUSG00000031995|Vega:OTTMUSG00000029771 +19144 Klk6 MGI:MGI:1343166|Ensembl:ENSMUSG00000050063|Vega:OTTMUSG00000022524 +19146 Tmprss15 MGI:MGI:1197523|Ensembl:ENSMUSG00000022857|Vega:OTTMUSG00000025321 +19152 Prtn3 MGI:MGI:893580|Ensembl:ENSMUSG00000057729|Vega:OTTMUSG00000035169 +19153 Prx MGI:MGI:108176|Ensembl:ENSMUSG00000053198|Vega:OTTMUSG00000023418 +19155 Npepps MGI:MGI:1101358|Ensembl:ENSMUSG00000001441|Vega:OTTMUSG00000002302 +19156 Psap MGI:MGI:97783|Ensembl:ENSMUSG00000004207|Vega:OTTMUSG00000016474 +19157 Cyth1 MGI:MGI:1334257|Ensembl:ENSMUSG00000017132|Vega:OTTMUSG00000003880 +19158 Cyth2 MGI:MGI:1334255|Ensembl:ENSMUSG00000003269|Vega:OTTMUSG00000023482 +19159 Cyth3 MGI:MGI:1335107|Ensembl:ENSMUSG00000018001|Vega:OTTMUSG00000023404 +19164 Psen1 MGI:MGI:1202717|Ensembl:ENSMUSG00000019969 +19165 Psen2 MGI:MGI:109284|Ensembl:ENSMUSG00000010609|Vega:OTTMUSG00000021488 +19166 Psma2 MGI:MGI:104885|Ensembl:ENSMUSG00000015671 +19167 Psma3 MGI:MGI:104883|Ensembl:ENSMUSG00000060073|Vega:OTTMUSG00000035110 +19170 Psmb1 MGI:MGI:104884|Ensembl:ENSMUSG00000014769 +19171 Psmb10 MGI:MGI:1096380|Ensembl:ENSMUSG00000031897|Vega:OTTMUSG00000062064 +19172 Psmb4 MGI:MGI:1098257|Ensembl:ENSMUSG00000005779|Vega:OTTMUSG00000019673 +19173 Psmb5 MGI:MGI:1194513|Ensembl:ENSMUSG00000022193 +19174 Psmb5-ps MGI:MGI:1194501 +19175 Psmb6 MGI:MGI:104880|Ensembl:ENSMUSG00000018286|Vega:OTTMUSG00000006054 +19177 Psmb7 MGI:MGI:107637|Ensembl:ENSMUSG00000026750|Vega:OTTMUSG00000012864 +19178 Psmb7-ps1 MGI:MGI:1096396 +19179 Psmc1 MGI:MGI:106054|Ensembl:ENSMUSG00000021178 +19181 Psmc2 MGI:MGI:109555|Ensembl:ENSMUSG00000028932|Vega:OTTMUSG00000024688 +19182 Psmc3 MGI:MGI:1098754|Ensembl:ENSMUSG00000002102|Vega:OTTMUSG00000014341 +19183 Psmc3ip MGI:MGI:1098610|Ensembl:ENSMUSG00000019303|Vega:OTTMUSG00000002691 +19184 Psmc5 MGI:MGI:105047|Ensembl:ENSMUSG00000020708|Vega:OTTMUSG00000003290 +19185 Psmd4 MGI:MGI:1201670|Ensembl:ENSMUSG00000005625|Vega:OTTMUSG00000019658 +19186 Psme1 MGI:MGI:1096367|Ensembl:ENSMUSG00000022216|Vega:OTTMUSG00000037625 +19188 Psme2 MGI:MGI:1096365|Ensembl:ENSMUSG00000079197|Vega:OTTMUSG00000034667 +19192 Psme3 MGI:MGI:1096366|Ensembl:ENSMUSG00000078652|Vega:OTTMUSG00000002795 +19193 Pipox MGI:MGI:1197006|Ensembl:ENSMUSG00000017453|Vega:OTTMUSG00000000072 +19194 Bpifa2 MGI:MGI:97787|Ensembl:ENSMUSG00000042459|Vega:OTTMUSG00000016849 +19197 Pspn MGI:MGI:1201684|Ensembl:ENSMUSG00000002664|Vega:OTTMUSG00000028994 +19200 Pstpip1 MGI:MGI:1321396|Ensembl:ENSMUSG00000032322|Vega:OTTMUSG00000026139 +19201 Pstpip2 MGI:MGI:1335088|Ensembl:ENSMUSG00000025429 +19202 Rhox6 MGI:MGI:1202888|Ensembl:ENSMUSG00000006200|Vega:OTTMUSG00000017130 +19204 Ptafr MGI:MGI:106066|Ensembl:ENSMUSG00000056529|Vega:OTTMUSG00000009789 +19205 Ptbp1 MGI:MGI:97791|Ensembl:ENSMUSG00000006498|Vega:OTTMUSG00000035444 +19206 Ptch1 MGI:MGI:105373|Ensembl:ENSMUSG00000021466|Vega:OTTMUSG00000050865 +19207 Ptch2 MGI:MGI:1095405|Ensembl:ENSMUSG00000028681|Vega:OTTMUSG00000009923 +19208 Ptcra MGI:MGI:104857|Ensembl:ENSMUSG00000036858|Vega:OTTMUSG00000045088 +19209 ptd MGI:MGI:97792 +19210 Ptdss1 MGI:MGI:1276575|Ensembl:ENSMUSG00000021518 +19211 Pten MGI:MGI:109583|Ensembl:ENSMUSG00000013663|Vega:OTTMUSG00000021203 +19212 Pter MGI:MGI:107372|Ensembl:ENSMUSG00000026730|Vega:OTTMUSG00000011123 +19213 Ptf1a MGI:MGI:1328312|Ensembl:ENSMUSG00000026735|Vega:OTTMUSG00000011489 +19214 Ptgdr MGI:MGI:102966|Ensembl:ENSMUSG00000071489|Vega:OTTMUSG00000036408 +19215 Ptgds MGI:MGI:99261|Ensembl:ENSMUSG00000015090|Vega:OTTMUSG00000012118 +19216 Ptger1 MGI:MGI:97793|Ensembl:ENSMUSG00000019464|Vega:OTTMUSG00000025957 +19217 Ptger2 MGI:MGI:97794|Ensembl:ENSMUSG00000037759|Vega:OTTMUSG00000036411 +19218 Ptger3 MGI:MGI:97795|Ensembl:ENSMUSG00000040016|Vega:OTTMUSG00000037109 +19219 Ptger4 MGI:MGI:104311|Ensembl:ENSMUSG00000039942|Vega:OTTMUSG00000027987 +19220 Ptgfr MGI:MGI:97796|Ensembl:ENSMUSG00000028036|Vega:OTTMUSG00000025720 +19221 Ptgfrn MGI:MGI:1277114|Ensembl:ENSMUSG00000027864|Vega:OTTMUSG00000007094 +19222 Ptgir MGI:MGI:99535|Ensembl:ENSMUSG00000043017|Vega:OTTMUSG00000033384 +19223 Ptgis MGI:MGI:1097156|Ensembl:ENSMUSG00000017969|Vega:OTTMUSG00000001169 +19224 Ptgs1 MGI:MGI:97797|Ensembl:ENSMUSG00000047250|Vega:OTTMUSG00000012142 +19225 Ptgs2 MGI:MGI:97798|Ensembl:ENSMUSG00000032487|Vega:OTTMUSG00000049547 +19226 Pth MGI:MGI:97799|Ensembl:ENSMUSG00000059077|Vega:OTTMUSG00000060361 +19227 Pthlh MGI:MGI:97800|Ensembl:ENSMUSG00000048776|Vega:OTTMUSG00000026067 +19228 Pth1r MGI:MGI:97801|Ensembl:ENSMUSG00000032492|Vega:OTTMUSG00000052494 +19229 Ptk2b MGI:MGI:104908|Ensembl:ENSMUSG00000059456|Vega:OTTMUSG00000016348 +19230 Twf1 MGI:MGI:1100520|Ensembl:ENSMUSG00000022451|Vega:OTTMUSG00000017538 +19231 Ptma MGI:MGI:97803|Ensembl:ENSMUSG00000026238|Vega:OTTMUSG00000048097 +19240 Tmsb10 MGI:MGI:109146|Ensembl:ENSMUSG00000079523|Vega:OTTMUSG00000022861 +19241 Tmsb4x MGI:MGI:99510|Ensembl:ENSMUSG00000049775|Vega:OTTMUSG00000019572 +19242 Ptn MGI:MGI:97804|Ensembl:ENSMUSG00000029838|Vega:OTTMUSG00000056195 +19243 Ptp4a1 MGI:MGI:1277096|Ensembl:ENSMUSG00000026064|Vega:OTTMUSG00000021326 +19244 Ptp4a2 MGI:MGI:1277117|Ensembl:ENSMUSG00000028788|Vega:OTTMUSG00000009511 +19245 Ptp4a3 MGI:MGI:1277098|Ensembl:ENSMUSG00000059895 +19246 Ptpn1 MGI:MGI:97805|Ensembl:ENSMUSG00000027540|Vega:OTTMUSG00000015956 +19247 Ptpn11 MGI:MGI:99511|Ensembl:ENSMUSG00000043733|Vega:OTTMUSG00000016267 +19248 Ptpn12 MGI:MGI:104673|Ensembl:ENSMUSG00000028771|Vega:OTTMUSG00000029737 +19249 Ptpn13 MGI:MGI:103293|Ensembl:ENSMUSG00000034573|Vega:OTTMUSG00000053726 +19250 Ptpn14 MGI:MGI:102467|Ensembl:ENSMUSG00000026604|Vega:OTTMUSG00000022087 +19252 Dusp1 MGI:MGI:105120|Ensembl:ENSMUSG00000024190|Vega:OTTMUSG00000020083 +19253 Ptpn18 MGI:MGI:108410|Ensembl:ENSMUSG00000026126|Vega:OTTMUSG00000049465 +19255 Ptpn2 MGI:MGI:97806|Ensembl:ENSMUSG00000024539|Vega:OTTMUSG00000029831 +19256 Ptpn20 MGI:MGI:1196295|Ensembl:ENSMUSG00000021940 +19258 Ptpn4 MGI:MGI:1099792|Ensembl:ENSMUSG00000026384|Vega:OTTMUSG00000035374 +19259 Ptpn5 MGI:MGI:97807|Ensembl:ENSMUSG00000030854|Vega:OTTMUSG00000016469 +19260 Ptpn22 MGI:MGI:107170|Ensembl:ENSMUSG00000027843|Vega:OTTMUSG00000022455 +19261 Sirpa MGI:MGI:108563|Ensembl:ENSMUSG00000037902|Vega:OTTMUSG00000015506 +19262 Ptpra MGI:MGI:97808|Ensembl:ENSMUSG00000027303|Vega:OTTMUSG00000015498 +19263 Ptprb MGI:MGI:97809|Ensembl:ENSMUSG00000020154 +19264 Ptprc MGI:MGI:97810|Ensembl:ENSMUSG00000026395|Vega:OTTMUSG00000043098 +19265 Ptprcap MGI:MGI:97811|Ensembl:ENSMUSG00000045826|Vega:OTTMUSG00000028312 +19266 Ptprd MGI:MGI:97812|Ensembl:ENSMUSG00000028399|Vega:OTTMUSG00000000304 +19267 Ptpre MGI:MGI:97813|Ensembl:ENSMUSG00000041836|Vega:OTTMUSG00000060356 +19268 Ptprf MGI:MGI:102695|Ensembl:ENSMUSG00000033295|Vega:OTTMUSG00000008720 +19270 Ptprg MGI:MGI:97814|Ensembl:ENSMUSG00000021745|Vega:OTTMUSG00000029429 +19271 Ptprj MGI:MGI:104574|Ensembl:ENSMUSG00000025314|Vega:OTTMUSG00000014165 +19272 Ptprk MGI:MGI:103310|Ensembl:ENSMUSG00000019889 +19273 Ptpru MGI:MGI:1321151|Ensembl:ENSMUSG00000028909|Vega:OTTMUSG00000009567 +19274 Ptprm MGI:MGI:102694|Ensembl:ENSMUSG00000033278 +19275 Ptprn MGI:MGI:102765|Ensembl:ENSMUSG00000026204|Vega:OTTMUSG00000048596 +19276 Ptprn2 MGI:MGI:107418|Ensembl:ENSMUSG00000056553|Vega:OTTMUSG00000048735 +19277 Ptpro MGI:MGI:1097152|Ensembl:ENSMUSG00000030223|Vega:OTTMUSG00000057549 +19279 Ptprr MGI:MGI:109559|Ensembl:ENSMUSG00000020151|Vega:OTTMUSG00000026109 +19280 Ptprs MGI:MGI:97815|Ensembl:ENSMUSG00000013236|Vega:OTTMUSG00000014929 +19281 Ptprt MGI:MGI:1321152|Ensembl:ENSMUSG00000053141|Vega:OTTMUSG00000015291 +19283 Ptprz1 MGI:MGI:97816|Ensembl:ENSMUSG00000068748|Vega:OTTMUSG00000055926 +19284 ptr MGI:MGI:97817 +19285 Cavin1 MGI:MGI:1277968|Ensembl:ENSMUSG00000004044|Vega:OTTMUSG00000002126 +19286 Pts MGI:MGI:1338783|Ensembl:ENSMUSG00000032067|Vega:OTTMUSG00000063068 +19288 Ptx3 MGI:MGI:104641|Ensembl:ENSMUSG00000027832|Vega:OTTMUSG00000043511 +19289 Igdcc3 MGI:MGI:1202390|Ensembl:ENSMUSG00000032394|Vega:OTTMUSG00000062620 +19290 Pura MGI:MGI:103079|Ensembl:ENSMUSG00000043991|Vega:OTTMUSG00000033186 +19291 Purb MGI:MGI:1338779|Ensembl:ENSMUSG00000094483|Vega:OTTMUSG00000005110 +19293 Pvalb MGI:MGI:97821|Ensembl:ENSMUSG00000005716|Vega:OTTMUSG00000031047 +19294 Nectin2 MGI:MGI:97822|Ensembl:ENSMUSG00000062300|Vega:OTTMUSG00000059280 +19296 Pvt1 MGI:MGI:97824|Ensembl:ENSMUSG00000097039 +19298 Pex19 MGI:MGI:1334458|Ensembl:ENSMUSG00000003464|Vega:OTTMUSG00000029601 +19299 Abcd3 MGI:MGI:1349216|Ensembl:ENSMUSG00000028127|Vega:OTTMUSG00000031086 +19300 Abcd4 MGI:MGI:1349217|Ensembl:ENSMUSG00000021240 +19301 Pxmp2 MGI:MGI:107487|Ensembl:ENSMUSG00000029499|Vega:OTTMUSG00000026216 +19302 Pex2 MGI:MGI:107486|Ensembl:ENSMUSG00000040374|Vega:OTTMUSG00000051256 +19303 Pxn MGI:MGI:108295|Ensembl:ENSMUSG00000029528|Vega:OTTMUSG00000014676 +19305 Pex5 MGI:MGI:1098808|Ensembl:ENSMUSG00000005069|Vega:OTTMUSG00000023142 +19306 py MGI:MGI:97827 +19309 Pygm MGI:MGI:97830|Ensembl:ENSMUSG00000032648|Vega:OTTMUSG00000018613 +19317 Qk MGI:MGI:97837|Ensembl:ENSMUSG00000062078 +19324 Rab1a MGI:MGI:97842|Ensembl:ENSMUSG00000020149|Vega:OTTMUSG00000005223 +19325 Rab10 MGI:MGI:105066|Ensembl:ENSMUSG00000020671 +19326 Rab11b MGI:MGI:99425|Ensembl:ENSMUSG00000077450|Vega:OTTMUSG00000037204 +19327 Rab11b-ps1 MGI:MGI:99426 +19328 Rab12 MGI:MGI:894284|Ensembl:ENSMUSG00000023460|Vega:OTTMUSG00000021023 +19329 Rab17 MGI:MGI:104640|Ensembl:ENSMUSG00000026304|Vega:OTTMUSG00000026752 +19330 Rab18 MGI:MGI:102790|Ensembl:ENSMUSG00000073639 +19331 Rab19 MGI:MGI:103292|Ensembl:ENSMUSG00000029923|Vega:OTTMUSG00000022161 +19332 Rab20 MGI:MGI:102789|Ensembl:ENSMUSG00000031504|Vega:OTTMUSG00000060750 +19334 Rab22a MGI:MGI:105072|Ensembl:ENSMUSG00000027519|Vega:OTTMUSG00000016371 +19335 Rab23 MGI:MGI:99833|Ensembl:ENSMUSG00000004768|Vega:OTTMUSG00000021871 +19336 Rab24 MGI:MGI:105065|Ensembl:ENSMUSG00000034789 +19337 Rab33a MGI:MGI:109493|Ensembl:ENSMUSG00000031104|Vega:OTTMUSG00000017541 +19338 Rab33b MGI:MGI:1330805|Ensembl:ENSMUSG00000027739|Vega:OTTMUSG00000051613 +19339 Rab3a MGI:MGI:97843|Ensembl:ENSMUSG00000031840|Vega:OTTMUSG00000016949 +19340 Rab3d MGI:MGI:97844|Ensembl:ENSMUSG00000019066|Vega:OTTMUSG00000031911 +19341 Rab4a MGI:MGI:105069|Ensembl:ENSMUSG00000019478|Vega:OTTMUSG00000030744 +19342 Rab4b MGI:MGI:105071|Ensembl:ENSMUSG00000053291|Vega:OTTMUSG00000022790 +19344 Rab5b MGI:MGI:105938|Ensembl:ENSMUSG00000000711 +19345 Rab5c MGI:MGI:105306|Ensembl:ENSMUSG00000019173|Vega:OTTMUSG00000002056 +19346 Rab6a MGI:MGI:894313|Ensembl:ENSMUSG00000030704|Vega:OTTMUSG00000016494 +19347 Dennd5a MGI:MGI:1201681|Ensembl:ENSMUSG00000035901|Vega:OTTMUSG00000026153 +19348 Kif20a MGI:MGI:1201682|Ensembl:ENSMUSG00000003779 +19349 Rab7 MGI:MGI:105068|Ensembl:ENSMUSG00000079477|Vega:OTTMUSG00000024646 +19350 Rab7-ps1 MGI:MGI:1276565 +19352 Rabggtb MGI:MGI:99537|Ensembl:ENSMUSG00000038975|Vega:OTTMUSG00000052933 +19353 Rac1 MGI:MGI:97845|Ensembl:ENSMUSG00000001847|Vega:OTTMUSG00000020705 +19354 Rac2 MGI:MGI:97846|Ensembl:ENSMUSG00000033220 +19355 Rad1 MGI:MGI:1316678|Ensembl:ENSMUSG00000022248|Vega:OTTMUSG00000035558 +19356 Rad17 MGI:MGI:1333807|Ensembl:ENSMUSG00000021635 +19357 Rad21 MGI:MGI:108016|Ensembl:ENSMUSG00000022314 +19358 Rad23a MGI:MGI:105126|Ensembl:ENSMUSG00000003813|Vega:OTTMUSG00000022270 +19359 Rad23b MGI:MGI:105128|Ensembl:ENSMUSG00000028426|Vega:OTTMUSG00000007227 +19360 Rad50 MGI:MGI:109292|Ensembl:ENSMUSG00000020380|Vega:OTTMUSG00000005644 +19361 Rad51 MGI:MGI:97890|Ensembl:ENSMUSG00000027323|Vega:OTTMUSG00000015759 +19362 Rad51ap1 MGI:MGI:1098224|Ensembl:ENSMUSG00000030346|Vega:OTTMUSG00000024111 +19363 Rad51b MGI:MGI:1099436|Ensembl:ENSMUSG00000059060 +19364 Rad51d MGI:MGI:1261809|Ensembl:ENSMUSG00000018841|Vega:OTTMUSG00000000932 +19365 Rad52 MGI:MGI:101949|Ensembl:ENSMUSG00000030166|Vega:OTTMUSG00000023589 +19366 Rad54l MGI:MGI:894697|Ensembl:ENSMUSG00000028702|Vega:OTTMUSG00000008554 +19367 Rad9a MGI:MGI:1328356|Ensembl:ENSMUSG00000024824 +19368 Raet1a MGI:MGI:109477 +19369 Raet1b MGI:MGI:109432 +19370 Raet1c MGI:MGI:109431 +19373 Rag1 MGI:MGI:97848|Ensembl:ENSMUSG00000061311|Vega:OTTMUSG00000014584 +19374 Rag2 MGI:MGI:97849|Ensembl:ENSMUSG00000032864|Vega:OTTMUSG00000014585 +19376 Rab34 MGI:MGI:104606|Ensembl:ENSMUSG00000002059|Vega:OTTMUSG00000000098 +19377 Rai1 MGI:MGI:103291|Ensembl:ENSMUSG00000062115|Vega:OTTMUSG00000005811 +19378 Aldh1a2 MGI:MGI:107928|Ensembl:ENSMUSG00000013584|Vega:OTTMUSG00000021057 +19383 Raly MGI:MGI:97850|Ensembl:ENSMUSG00000027593|Vega:OTTMUSG00000015980 +19384 Ran MGI:MGI:1333112|Ensembl:ENSMUSG00000029430|Vega:OTTMUSG00000016923 +19385 Ranbp1 MGI:MGI:96269|Ensembl:ENSMUSG00000005732|Vega:OTTMUSG00000026021 +19386 Ranbp2 MGI:MGI:894323|Ensembl:ENSMUSG00000003226 +19387 Rangap1 MGI:MGI:103071|Ensembl:ENSMUSG00000022391 +19395 Rasgrp2 MGI:MGI:1333849|Ensembl:ENSMUSG00000032946|Vega:OTTMUSG00000018627 +19400 Rapsn MGI:MGI:99422|Ensembl:ENSMUSG00000002104|Vega:OTTMUSG00000014338 +19401 Rara MGI:MGI:97856|Ensembl:ENSMUSG00000037992|Vega:OTTMUSG00000006440 +19403 Rare1 MGI:MGI:109145 +19404 Rare2 MGI:MGI:109144 +19405 Rare3 MGI:MGI:109143 +19406 Rare4 MGI:MGI:109142 +19407 Rare5 MGI:MGI:109141 +19408 Rare6 MGI:MGI:109140 +19409 Rare7 MGI:MGI:109139 +19410 Rare8 MGI:MGI:109138 +19411 Rarg MGI:MGI:97858|Ensembl:ENSMUSG00000001288|Vega:OTTMUSG00000029220 +19412 ras MGI:MGI:97859 +19414 Rasa3 MGI:MGI:1197013|Ensembl:ENSMUSG00000031453|Vega:OTTMUSG00000029877 +19415 Rasal1 MGI:MGI:1330842|Ensembl:ENSMUSG00000029602|Vega:OTTMUSG00000025930 +19416 Rasd1 MGI:MGI:1270848|Ensembl:ENSMUSG00000049892|Vega:OTTMUSG00000005806 +19417 Rasgrf1 MGI:MGI:99694|Ensembl:ENSMUSG00000032356|Vega:OTTMUSG00000046289 +19418 Rasgrf2 MGI:MGI:109137|Ensembl:ENSMUSG00000021708 +19419 Rasgrp1 MGI:MGI:1314635|Ensembl:ENSMUSG00000027347|Vega:OTTMUSG00000015228 +19428 Rasl2-9 MGI:MGI:104605|Ensembl:ENSMUSG00000083649|Vega:OTTMUSG00000022852 +19434 Rax MGI:MGI:109632|Ensembl:ENSMUSG00000024518 +19435 Rb(1.10)10Bnr MGI:MGI:103623 +19436 Rb(1.10)10Bnr MGI:MGI:103624 +19437 Rb(1.11)2Mpl MGI:MGI:103625 +19438 Rb(1.11)2Mpl MGI:MGI:103626 +19439 Rb(1.15)2Ct MGI:MGI:103627 +19440 Rb(1.15)2Ct MGI:MGI:103628 +19441 Rb(1.18)10Rma MGI:MGI:103629 +19442 Rb(1.18)10Rma MGI:MGI:103630 +19443 Rb(1.2)18Lub MGI:MGI:103613 +19444 Rb(1.2)18Lub MGI:MGI:103614 +19445 Rb(1.2)5H MGI:MGI:103611 +19446 Rb(1.2)5H MGI:MGI:103612 +19447 Rb(1.3)1Bnr MGI:MGI:103615 +19448 Rb(1.3)1Bnr MGI:MGI:103616 +19449 Rb(1.3)1Ei MGI:MGI:103617 +19450 Rb(1.3)1Ei MGI:MGI:103618 +19451 Rb(1.3)1Lub MGI:MGI:103619 +19452 Rb(1.3)1Lub MGI:MGI:103620 +19453 Rb(1.7)1Rma MGI:MGI:103621 +19454 Rb(1.7)1Rma MGI:MGI:103622 +19455 Rb(10.11)5Rma MGI:MGI:104058 +19456 Rb(10.11)5Rma MGI:MGI:104059 +19457 Rb(10.11)8Bnr MGI:MGI:104060 +19458 Rb(10.11)8Bnr MGI:MGI:104061 +19459 Rb(10.12)17Rma MGI:MGI:104064 +19460 Rb(10.12)17Rma MGI:MGI:104065 +19461 Rb(10.12)5Lub MGI:MGI:104062 +19462 Rb(10.12)5Lub MGI:MGI:104063 +19463 Rb(10.14)1Ad MGI:MGI:104066 +19464 Rb(10.14)1Ad MGI:MGI:104067 +19465 Rb(10.15)23Lub MGI:MGI:104068 +19466 Rb(10.15)23Lub MGI:MGI:104069 +19467 Rb(10.17)9Mpl MGI:MGI:104070 +19468 Rb(10.17)9Mpl MGI:MGI:104071 +19469 Rb(11.13)4Bnr MGI:MGI:104098 +19470 Rb(11.13)4Bnr MGI:MGI:104099 +19471 Rb(11.13)6Lub MGI:MGI:104100 +19472 Rb(11.13)6Lub MGI:MGI:104101 +19473 Rb(11.13)6Tu MGI:MGI:104102 +19474 Rb(11.13)6Tu MGI:MGI:104103 +19475 Rb(11.14)1Dn MGI:MGI:104104 +19476 Rb(11.14)1Dn MGI:MGI:104105 +19477 Rb(11.16)2H MGI:MGI:104106 +19478 Rb(11.16)2H MGI:MGI:104107 +19479 Rb(12.13)15Tu MGI:MGI:104129 +19480 Rb(12.13)15Tu MGI:MGI:104130 +19481 Rb(12.13)3Ct MGI:MGI:104127 +19482 Rb(12.13)3Ct MGI:MGI:104128 +19483 Rb(12.14)8Rma MGI:MGI:104131 +19484 Rb(12.14)8Rma MGI:MGI:104132 +19485 Rb(13.15)10Mpl MGI:MGI:104143 +19486 Rb(13.15)10Mpl MGI:MGI:104144 +19487 Rb(13.16)1Mpl MGI:MGI:104145 +19488 Rb(13.16)1Mpl MGI:MGI:104146 +19489 Rb(15.17)64Lub MGI:MGI:104185 +19490 Rb(15.17)64Lub MGI:MGI:104186 +19491 Rb(16.17)32Lub MGI:MGI:104204 +19492 Rb(16.17)32Lub MGI:MGI:104205 +19493 Rb(16.17)54Lub MGI:MGI:104206 +19494 Rb(16.17)54Lub MGI:MGI:104207 +19495 Rb(16.17)74Lub MGI:MGI:104208 +19496 Rb(16.17)74Lub MGI:MGI:104209 +19497 Rb(16.17)75Lub MGI:MGI:104210 +19498 Rb(16.17)75Lub MGI:MGI:104211 +19499 Rb(16.17)7Bnr MGI:MGI:104200 +19500 Rb(16.17)7Bnr MGI:MGI:104201 +19501 Rb(16.17)8Lub MGI:MGI:104202 +19502 Rb(16.17)8Lub MGI:MGI:104203 +19503 Rb(16.19)1Bu MGI:MGI:104212 +19504 Rb(16.19)1Bu MGI:MGI:104213 +19505 Rb(2.16)3Mpl MGI:MGI:103680 +19506 Rb(2.16)3Mpl MGI:MGI:103681 +19507 Rb(2.17)11Rma MGI:MGI:103684 +19508 Rb(2.17)11Rma MGI:MGI:103685 +19509 Rb(2.17)4H MGI:MGI:103682 +19510 Rb(2.17)4H MGI:MGI:103683 +19511 Rb(2.18)6Rma MGI:MGI:103686 +19512 Rb(2.18)6Rma MGI:MGI:103687 +19513 Rb(2.5)2Tu MGI:MGI:103674 +19514 Rb(2.5)2Tu MGI:MGI:103675 +19515 Rb(2.6)4Iem MGI:MGI:103676 +19516 Rb(2.6)4Iem MGI:MGI:103677 +19517 Rb(2.8)2Lub MGI:MGI:103678 +19518 Rb(2.8)2Lub MGI:MGI:103679 +19519 Rb(3.12)4Mpl MGI:MGI:103753 +19520 Rb(3.12)4Mpl MGI:MGI:103754 +19521 Rb(3.14)7Tu MGI:MGI:103755 +19522 Rb(3.14)7Tu MGI:MGI:103756 +19523 Rb(3.15)2Rk MGI:MGI:103757 +19524 Rb(3.15)2Rk MGI:MGI:103758 +19525 Rb(3.5)1Icg MGI:MGI:103743 +19526 Rb(3.5)1Icg MGI:MGI:103744 +19527 Rb(3.6)3Tu MGI:MGI:103745 +19528 Rb(3.6)3Tu MGI:MGI:103746 +19529 Rb(3.8)2Ei MGI:MGI:103747 +19530 Rb(3.8)2Ei MGI:MGI:103748 +19531 Rb(3.8)2Rma MGI:MGI:103749 +19532 Rb(3.8)2Rma MGI:MGI:103750 +19533 Rb(3.9)12Lub MGI:MGI:103751 +19534 Rb(3.9)12Lub MGI:MGI:103752 +19535 Rb(4.10)8Tu MGI:MGI:103787 +19536 Rb(4.10)8Tu MGI:MGI:103788 +19537 Rb(4.11)12Rma MGI:MGI:103789 +19538 Rb(4.11)12Rma MGI:MGI:103790 +19539 Rb(4.12)1Nam MGI:MGI:103791 +19540 Rb(4.12)1Nam MGI:MGI:103792 +19541 Rb(4.12)1Tu MGI:MGI:103793 +19542 Rb(4.12)1Tu MGI:MGI:103794 +19543 Rb(4.12)9Bnr MGI:MGI:103795 +19544 Rb(4.12)9Bnr MGI:MGI:103796 +19545 Rb(4.14)11Tu MGI:MGI:103799 +19546 Rb(4.14)11Tu MGI:MGI:103800 +19547 Rb(4.14)8H MGI:MGI:103797 +19548 Rb(4.14)8H MGI:MGI:103798 +19549 Rb(4.15)1Rk MGI:MGI:103801 +19550 Rb(4.15)1Rk MGI:MGI:103802 +19551 Rb(4.15)4Rma MGI:MGI:103803 +19552 Rb(4.15)4Rma MGI:MGI:103804 +19553 Rb(4.17)13Lub MGI:MGI:103805 +19554 Rb(4.17)13Lub MGI:MGI:103806 +19555 Rb(4.18)3H MGI:MGI:103807 +19556 Rb(4.18)3H MGI:MGI:103808 +19557 Rb(4.6)2Bnr MGI:MGI:103783 +19558 Rb(4.6)2Bnr MGI:MGI:103784 +19559 Rb(4.6)5Mpl MGI:MGI:103785 +19560 Rb(4.6)5Mpl MGI:MGI:103786 +19561 Rb(5.10)3Nam MGI:MGI:103840 +19562 Rb(5.10)3Nam MGI:MGI:103841 +19563 Rb(5.13)70Lub MGI:MGI:103842 +19564 Rb(5.13)70Lub MGI:MGI:103843 +19565 Rb(5.14)21Lub MGI:MGI:103846 +19566 Rb(5.14)21Lub MGI:MGI:103847 +19567 Rb(5.14)6Mpl MGI:MGI:103844 +19568 Rb(5.14)6Mpl MGI:MGI:103845 +19569 Rb(5.15)12Tu MGI:MGI:103852 +19570 Rb(5.15)12Tu MGI:MGI:103853 +19571 Rb(5.15)15Rma MGI:MGI:103854 +19572 Rb(5.15)15Rma MGI:MGI:103855 +19573 Rb(5.15)3Bnr MGI:MGI:103848 +19574 Rb(5.15)3Bnr MGI:MGI:103849 +19575 Rb(5.15)4Lub MGI:MGI:103850 +19576 Rb(5.15)4Lub MGI:MGI:103851 +19577 Rb(5.17)7Rma MGI:MGI:103856 +19578 Rb(5.17)7Rma MGI:MGI:103857 +19579 Rb(5.19)1Wh MGI:MGI:103858 +19580 Rb(5.19)1Wh MGI:MGI:103859 +19581 Rb(5.6)1Ty MGI:MGI:103838 +19582 Rb(5.6)1Ty MGI:MGI:103839 +19583 Rb(6.10)13Tu MGI:MGI:103893 +19584 Rb(6.10)13Tu MGI:MGI:103894 +19585 Rb(6.12)3Sic MGI:MGI:103895 +19586 Rb(6.12)3Sic MGI:MGI:103896 +19587 Rb(6.13)1H MGI:MGI:103897 +19588 Rb(6.13)1H MGI:MGI:103898 +19589 Rb(6.13)3Rma MGI:MGI:103899 +19590 Rb(6.13)3Rma MGI:MGI:103900 +19591 Rb(6.13)9Tu MGI:MGI:103901 +19592 Rb(6.13)9Tu MGI:MGI:103902 +19593 Rb(6.15)1Ald MGI:MGI:103903 +19594 Rb(6.15)1Ald MGI:MGI:103904 +19595 Rb(6.16)24Lub MGI:MGI:103905 +19596 Rb(6.16)24Lub MGI:MGI:103906 +19597 Rb(6.18)2Dn MGI:MGI:103907 +19598 Rb(6.18)2Dn MGI:MGI:103908 +19599 Rb(6.19)2Icg MGI:MGI:103909 +19600 Rb(6.19)2Icg MGI:MGI:103910 +19601 Rb(6.7)13Rma MGI:MGI:103891 +19602 Rb(6.7)13Rma MGI:MGI:103892 +19603 Rb(7.13)1Oxf MGI:MGI:103947 +19604 Rb(7.13)1Oxf MGI:MGI:103948 +19605 Rb(7.18)7Mpl MGI:MGI:103949 +19606 Rb(7.18)7Mpl MGI:MGI:103950 +19607 Rb(7.18)9Lub MGI:MGI:103951 +19608 Rb(7.18)9Lub MGI:MGI:103952 +19609 Rb(7.8)12Bnr MGI:MGI:103945 +19610 Rb(7.8)12Bnr MGI:MGI:103946 +19611 Rb(8.12)22Lub MGI:MGI:103994 +19612 Rb(8.12)22Lub MGI:MGI:103995 +19613 Rb(8.12)5Bnr MGI:MGI:103992 +19614 Rb(8.12)5Bnr MGI:MGI:103993 +19615 Rb(8.14)16Rma MGI:MGI:103996 +19616 Rb(8.14)16Rma MGI:MGI:103997 +19617 Rb(8.17)1Iem MGI:MGI:103998 +19618 Rb(8.17)1Iem MGI:MGI:103999 +19619 Rb(8.17)38Lub MGI:MGI:104002 +19620 Rb(8.17)38Lub MGI:MGI:104003 +19621 Rb(8.17)6Sic MGI:MGI:104000 +19622 Rb(8.17)6Sic MGI:MGI:104001 +19623 Rb(8.19)1Ct MGI:MGI:104004 +19624 Rb(8.19)1Ct MGI:MGI:104005 +19625 Rb(8.9)8Mpl MGI:MGI:103990 +19626 Rb(8.9)8Mpl MGI:MGI:103991 +19627 Rb(9.11)14Tu MGI:MGI:104022 +19628 Rb(9.11)14Tu MGI:MGI:104023 +19629 Rb(9.12)10Tu MGI:MGI:104026 +19630 Rb(9.12)10Tu MGI:MGI:104027 +19631 Rb(9.12)1Cam MGI:MGI:104024 +19632 Rb(9.12)1Cam MGI:MGI:104025 +19633 Rb(9.14)6Bnr MGI:MGI:104028 +19634 Rb(9.14)6Bnr MGI:MGI:104029 +19635 Rb(9.16)9Rma MGI:MGI:104030 +19636 Rb(9.16)9Rma MGI:MGI:104031 +19637 Rb(9.19)163H MGI:MGI:104032 +19638 Rb(9.19)163H MGI:MGI:104033 +19639 Rb(X.12)7H MGI:MGI:104244 +19640 Rb(X.12)7H MGI:MGI:104245 +19641 Rb(X.2)2Ad MGI:MGI:104241 +19642 Rb(X.2)2Ad MGI:MGI:104240 +19643 Rb(X.9)6H MGI:MGI:104243 +19644 Rb(X.9)6H MGI:MGI:104242 +19645 Rb1 MGI:MGI:97874|Ensembl:ENSMUSG00000022105|Vega:OTTMUSG00000036132 +19646 Rbbp4 MGI:MGI:1194912|Ensembl:ENSMUSG00000057236|Vega:OTTMUSG00000009619 +19647 Rbbp6 MGI:MGI:894835|Ensembl:ENSMUSG00000030779|Vega:OTTMUSG00000025360 +19649 Robo3 MGI:MGI:1343102|Ensembl:ENSMUSG00000032128|Vega:OTTMUSG00000016764 +19650 Rbl1 MGI:MGI:103300|Ensembl:ENSMUSG00000027641|Vega:OTTMUSG00000016175 +19651 Rbl2 MGI:MGI:105085|Ensembl:ENSMUSG00000031666|Vega:OTTMUSG00000031746 +19652 Rbm3 MGI:MGI:1099460|Ensembl:ENSMUSG00000031167|Vega:OTTMUSG00000018091 +19653 Rbm4 MGI:MGI:1100865|Ensembl:ENSMUSG00000094936|Vega:OTTMUSG00000042309 +19654 Rbm6 MGI:MGI:1338037|Ensembl:ENSMUSG00000032582|Vega:OTTMUSG00000043552 +19655 Rbmx MGI:MGI:1343044|Ensembl:ENSMUSG00000031134|Vega:OTTMUSG00000017821 +19656 Rbmxl1 MGI:MGI:1343045|Ensembl:ENSMUSG00000037070|Vega:OTTMUSG00000061282 +19657 Rbmy MGI:MGI:104732|Ensembl:ENSMUSG00000094658|Vega:OTTMUSG00000045391 +19659 Rbp1 MGI:MGI:97876|Ensembl:ENSMUSG00000046402|Vega:OTTMUSG00000047579 +19660 Rbp2 MGI:MGI:97877|Ensembl:ENSMUSG00000032454|Vega:OTTMUSG00000047580 +19661 Rbp3 MGI:MGI:97878|Ensembl:ENSMUSG00000041534 +19662 Rbp4 MGI:MGI:97879|Ensembl:ENSMUSG00000024990 +19663 Rbpms MGI:MGI:1334446|Ensembl:ENSMUSG00000031586|Vega:OTTMUSG00000043555 +19664 Rbpj MGI:MGI:96522|Ensembl:ENSMUSG00000039191|Vega:OTTMUSG00000054613 +19665 Rbpsuh-ps1 MGI:MGI:96523 +19666 Rbpsuh-ps2 MGI:MGI:96524 +19667 Rbpsuh-rs3 MGI:MGI:96525 +19668 Rbpjl MGI:MGI:1196616|Ensembl:ENSMUSG00000017007|Vega:OTTMUSG00000001156 +19671 Rce1 MGI:MGI:1336895|Ensembl:ENSMUSG00000024889 +19672 Rcn1 MGI:MGI:104559|Ensembl:ENSMUSG00000005973|Vega:OTTMUSG00000014990 +19674 Rcvrn MGI:MGI:97883|Ensembl:ENSMUSG00000020907|Vega:OTTMUSG00000005933 +19679 Pitpnm2 MGI:MGI:1336192|Ensembl:ENSMUSG00000029406|Vega:OTTMUSG00000033871 +19682 Rdh5 MGI:MGI:1201412|Ensembl:ENSMUSG00000025350|Vega:OTTMUSG00000033473 +19683 Rdh16 MGI:MGI:1201375|Ensembl:ENSMUSG00000069456|Vega:OTTMUSG00000027661 +19684 Rdx MGI:MGI:97887|Ensembl:ENSMUSG00000032050|Vega:OTTMUSG00000063089 +19687 Rfc1 MGI:MGI:97891|Ensembl:ENSMUSG00000029191|Vega:OTTMUSG00000038036 +19691 Recql MGI:MGI:103021|Ensembl:ENSMUSG00000030243|Vega:OTTMUSG00000022473 +19692 Reg1 MGI:MGI:97895|Ensembl:ENSMUSG00000059654|Vega:OTTMUSG00000057466 +19693 Reg2 MGI:MGI:97896|Ensembl:ENSMUSG00000023140|Vega:OTTMUSG00000057465 +19694 Reg3a MGI:MGI:109408|Ensembl:ENSMUSG00000079516|Vega:OTTMUSG00000057464 +19695 Reg3g MGI:MGI:109406|Ensembl:ENSMUSG00000030017|Vega:OTTMUSG00000042157 +19696 Rel MGI:MGI:97897|Ensembl:ENSMUSG00000020275|Vega:OTTMUSG00000005282 +19697 Rela MGI:MGI:103290|Ensembl:ENSMUSG00000024927|Vega:OTTMUSG00000016639 +19698 Relb MGI:MGI:103289|Ensembl:ENSMUSG00000002983|Vega:OTTMUSG00000020490 +19699 Reln MGI:MGI:103022|Ensembl:ENSMUSG00000042453|Vega:OTTMUSG00000030584 +19700 Rem1 MGI:MGI:1097696|Ensembl:ENSMUSG00000000359|Vega:OTTMUSG00000015816 +19701 Ren1 MGI:MGI:97898|Ensembl:ENSMUSG00000070645|Vega:OTTMUSG00000021617 +19702 Ren2 MGI:MGI:97899 +19703 Renbp MGI:MGI:105940|Ensembl:ENSMUSG00000031387|Vega:OTTMUSG00000017682 +19704 Upf1 MGI:MGI:107995|Ensembl:ENSMUSG00000058301|Vega:OTTMUSG00000062217 +19707 Reps1 MGI:MGI:1196373|Ensembl:ENSMUSG00000019854|Vega:OTTMUSG00000033574 +19708 Dpf2 MGI:MGI:109529|Ensembl:ENSMUSG00000024826|Vega:OTTMUSG00000026653 +19711 Resp18 MGI:MGI:1098222|Ensembl:ENSMUSG00000033061|Vega:OTTMUSG00000024507 +19712 Rest MGI:MGI:104897|Ensembl:ENSMUSG00000029249|Vega:OTTMUSG00000021414 +19713 Ret MGI:MGI:97902|Ensembl:ENSMUSG00000030110|Vega:OTTMUSG00000056769 +19714 Rev3l MGI:MGI:1337131|Ensembl:ENSMUSG00000019841|Vega:OTTMUSG00000031765 +19716 Bex1 MGI:MGI:1328321|Ensembl:ENSMUSG00000050071|Vega:OTTMUSG00000018673 +19718 Rfc2 MGI:MGI:1341868|Ensembl:ENSMUSG00000023104|Vega:OTTMUSG00000055749 +19719 Rfng MGI:MGI:894275|Ensembl:ENSMUSG00000025158|Vega:OTTMUSG00000004135 +19720 Trim27 MGI:MGI:97904|Ensembl:ENSMUSG00000021326|Vega:OTTMUSG00000032925 +19724 Rfx1 MGI:MGI:105982|Ensembl:ENSMUSG00000031706|Vega:OTTMUSG00000061193 +19725 Rfx2 MGI:MGI:106583|Ensembl:ENSMUSG00000024206 +19726 Rfx3 MGI:MGI:106582|Ensembl:ENSMUSG00000040929|Vega:OTTMUSG00000037650 +19727 Rfxank MGI:MGI:1333865|Ensembl:ENSMUSG00000036120|Vega:OTTMUSG00000062215 +19729 Slc50a1 MGI:MGI:107417|Ensembl:ENSMUSG00000027953|Vega:OTTMUSG00000021858 +19730 Ralgds MGI:MGI:107485|Ensembl:ENSMUSG00000026821|Vega:OTTMUSG00000011643 +19731 Rgl1 MGI:MGI:107484|Ensembl:ENSMUSG00000026482|Vega:OTTMUSG00000022514 +19732 Rgl2 MGI:MGI:107483|Ensembl:ENSMUSG00000041354|Vega:OTTMUSG00000037071 +19733 Rgn MGI:MGI:108024|Ensembl:ENSMUSG00000023070|Vega:OTTMUSG00000017082 +19734 Rgs16 MGI:MGI:108407|Ensembl:ENSMUSG00000026475|Vega:OTTMUSG00000020889 +19735 Rgs2 MGI:MGI:1098271|Ensembl:ENSMUSG00000026360|Vega:OTTMUSG00000020882 +19736 Rgs4 MGI:MGI:108409|Ensembl:ENSMUSG00000038530|Vega:OTTMUSG00000020909 +19737 Rgs5 MGI:MGI:1098434|Ensembl:ENSMUSG00000026678|Vega:OTTMUSG00000020901 +19739 Rgs9 MGI:MGI:1338824|Ensembl:ENSMUSG00000020599|Vega:OTTMUSG00000003137 +19742 rh MGI:MGI:97911 +19743 Rhag MGI:MGI:1202713|Ensembl:ENSMUSG00000023926|Vega:OTTMUSG00000026302 +19744 Rheb MGI:MGI:97912|Ensembl:ENSMUSG00000028945|Vega:OTTMUSG00000023527 +19746 Rhd MGI:MGI:1202882|Ensembl:ENSMUSG00000028825|Vega:OTTMUSG00000011094 +19752 Rnase1 MGI:MGI:97919|Ensembl:ENSMUSG00000035896 +19762 Rit2 MGI:MGI:108054|Ensembl:ENSMUSG00000057455|Vega:OTTMUSG00000033066 +19763 Ring1 MGI:MGI:1101770|Ensembl:ENSMUSG00000024325|Vega:OTTMUSG00000037105 +19765 Ralbp1 MGI:MGI:108466|Ensembl:ENSMUSG00000024096 +19766 Ripk1 MGI:MGI:108212|Ensembl:ENSMUSG00000021408|Vega:OTTMUSG00000035489 +19769 Rit1 MGI:MGI:108053|Ensembl:ENSMUSG00000028057|Vega:OTTMUSG00000035185 +19771 Rlbp1 MGI:MGI:97930|Ensembl:ENSMUSG00000039194|Vega:OTTMUSG00000058562 +19773 Rln1 MGI:MGI:97931|Ensembl:ENSMUSG00000039097|Vega:OTTMUSG00000044339 +19775 Xpr1 MGI:MGI:97932|Ensembl:ENSMUSG00000026469|Vega:OTTMUSG00000022503 +19777 Uri1 MGI:MGI:1342294|Ensembl:ENSMUSG00000030421|Vega:OTTMUSG00000042426 +19782 Rmrp MGI:MGI:97937|Ensembl:ENSMUSG00000088088 +19783 Rprl1 MGI:MGI:105105|Ensembl:ENSMUSG00000106222 +19784 Rprl2 MGI:MGI:105104 +19785 Rprl3 MGI:MGI:105103 +19789 rmy MGI:MGI:97941 +19791 Rn18s MGI:MGI:97943 +19799 Rn4.5s MGI:MGI:97946 +19800 Rn4.5s-ps1 MGI:MGI:97947 +19801 Rn4.5s-ps2 MGI:MGI:97948 +19802 Rn4.5s-ps3 MGI:MGI:97944 +19803 Rn4.5s-ps4 MGI:MGI:97945 +19804 Rn5s MGI:MGI:97949|Ensembl:ENSMUSG00000096406 +19805 Rn5s-ps1 MGI:MGI:99528 +19817 Rn7sk MGI:MGI:103186|Ensembl:ENSMUSG00000065037 +19819 Rnaseh1 MGI:MGI:1335073|Ensembl:ENSMUSG00000020630 +19820 Rlim MGI:MGI:1342291|Ensembl:ENSMUSG00000056537|Vega:OTTMUSG00000018399 +19821 Rnf2 MGI:MGI:1101759|Ensembl:ENSMUSG00000026484|Vega:OTTMUSG00000049593 +19822 Rnf4 MGI:MGI:1201691|Ensembl:ENSMUSG00000029110|Vega:OTTMUSG00000043581 +19823 Rnf7 MGI:MGI:1337096|Ensembl:ENSMUSG00000051234|Vega:OTTMUSG00000022972 +19824 Trim10 MGI:MGI:1338757|Ensembl:ENSMUSG00000073400|Vega:OTTMUSG00000037380 +19826 Rnps1 MGI:MGI:97960|Ensembl:ENSMUSG00000034681 +19842 Rnu1a1 MGI:MGI:97972|Ensembl:ENSMUSG00000095969 +19844 Rnu1b1 MGI:MGI:97974|Ensembl:ENSMUSG00000095580 +19845 Rnu1b2 MGI:MGI:104624|Ensembl:ENSMUSG00000093834 +19847 Rnu1b6 MGI:MGI:104604|Ensembl:ENSMUSG00000065773 +19848 Rnu2-10 MGI:MGI:97976|Ensembl:ENSMUSG00000065944 +19850 Rnu3a MGI:MGI:97977 +19852 Rnu3b-ps1 MGI:MGI:97979 +19853 Rnu3b-ps2 MGI:MGI:97980 +19854 Rnu3b-ps3 MGI:MGI:97981 +19858 Rnu3b1 MGI:MGI:97985|Ensembl:ENSMUSG00000098943|Ensembl:ENSMUSG00000105025 +19859 Rnu3b2 MGI:MGI:97986|Ensembl:ENSMUSG00000098925|Ensembl:ENSMUSG00000105115 +19860 Rnu3b3 MGI:MGI:97987|Ensembl:ENSMUSG00000099291|Ensembl:ENSMUSG00000104856 +19861 Rnu3b4 MGI:MGI:97988|Ensembl:ENSMUSG00000098641|Ensembl:ENSMUSG00000104896 +19862 Rnu6 MGI:MGI:97989|Ensembl:ENSMUSG00000095132 +19863 Rnu6-ps1 MGI:MGI:97990 +19864 Rnu6-ps2 MGI:MGI:97991 +19866 Rnu7 MGI:MGI:97992|Ensembl:ENSMUSG00000089083 +19867 Rnu7-ps1 MGI:MGI:97993 +19868 Rnu7-ps2 MGI:MGI:97994 +19869 Rnu7-ps3 MGI:MGI:105101 +19870 Snord73a MGI:MGI:1321388|Ensembl:ENSMUSG00000064984 +19871 Rnu73b MGI:MGI:1321387|Ensembl:ENSMUSG00000064390 +19872 Rny1 MGI:MGI:97995|Ensembl:ENSMUSG00000065701 +19874 Rny3 MGI:MGI:107304|Ensembl:ENSMUSG00000064945 +19875 ro MGI:MGI:97996 +19876 Robo1 MGI:MGI:1274781|Ensembl:ENSMUSG00000022883|Vega:OTTMUSG00000017054 +19877 Rock1 MGI:MGI:107927|Ensembl:ENSMUSG00000024290 +19878 Rock2 MGI:MGI:107926|Ensembl:ENSMUSG00000020580 +19879 Slc22a8 MGI:MGI:1336187|Ensembl:ENSMUSG00000063796 +19880 rol MGI:MGI:97997 +19881 Rom1 MGI:MGI:97998|Ensembl:ENSMUSG00000071648 +19882 Mst1r MGI:MGI:99614|Ensembl:ENSMUSG00000032584|Vega:OTTMUSG00000050789 +19883 Rora MGI:MGI:104661|Ensembl:ENSMUSG00000032238|Vega:OTTMUSG00000023055 +19885 Rorc MGI:MGI:104856|Ensembl:ENSMUSG00000028150|Vega:OTTMUSG00000022692 +19886 Ros1 MGI:MGI:97999|Ensembl:ENSMUSG00000019893 +19888 Rp1 MGI:MGI:1341105|Ensembl:ENSMUSG00000025900|Vega:OTTMUSG00000049985 +19889 Rp2 MGI:MGI:1277953|Ensembl:ENSMUSG00000060090|Vega:OTTMUSG00000017057 +19891 Rpa2 MGI:MGI:1339939|Ensembl:ENSMUSG00000028884|Vega:OTTMUSG00000009961 +19892 Rpe65 MGI:MGI:98001|Ensembl:ENSMUSG00000028174|Vega:OTTMUSG00000052823 +19893 Rpgr MGI:MGI:1344037|Ensembl:ENSMUSG00000031174|Vega:OTTMUSG00000016902 +19894 Rph3a MGI:MGI:102788|Ensembl:ENSMUSG00000029608|Vega:OTTMUSG00000056243 +19895 Rpia MGI:MGI:103254|Ensembl:ENSMUSG00000053604|Vega:OTTMUSG00000022844 +19896 Rpl10a MGI:MGI:1343877|Ensembl:ENSMUSG00000037805|Vega:OTTMUSG00000023382 +19897 Gm10275 MGI:MGI:3704354 +19899 Rpl18 MGI:MGI:98003|Ensembl:ENSMUSG00000059070|Vega:OTTMUSG00000023185 +19921 Rpl19 MGI:MGI:98020|Ensembl:ENSMUSG00000017404|Vega:OTTMUSG00000002909 +19933 Rpl21 MGI:MGI:1278340|Ensembl:ENSMUSG00000041453|Vega:OTTMUSG00000024591 +19934 Rpl22 MGI:MGI:99262|Ensembl:ENSMUSG00000028936|Vega:OTTMUSG00000010577 +19935 Mrpl23 MGI:MGI:1196612|Ensembl:ENSMUSG00000037772|Vega:OTTMUSG00000018798 +19941 Rpl26 MGI:MGI:106022|Ensembl:ENSMUSG00000060938|Vega:OTTMUSG00000005949 +19942 Rpl27 MGI:MGI:98036|Ensembl:ENSMUSG00000063316|Vega:OTTMUSG00000002868 +19943 Rpl28 MGI:MGI:101839|Ensembl:ENSMUSG00000030432|Vega:OTTMUSG00000022993 +19944 Rpl29 MGI:MGI:99687|Ensembl:ENSMUSG00000048758|Vega:OTTMUSG00000033747 +19945 Rpl29-ps1 MGI:MGI:99686 +19946 Rpl30 MGI:MGI:98037|Ensembl:ENSMUSG00000058600|Vega:OTTMUSG00000023325 +19947 Rpl30-ps1 MGI:MGI:1321399 +19948 Rpl30-ps2 MGI:MGI:1321400 +19949 Rpl30-ps3 MGI:MGI:1321401 +19951 Rpl32 MGI:MGI:98038|Ensembl:ENSMUSG00000057841|Vega:OTTMUSG00000022927 +19952 Rpl32-ps MGI:MGI:98039 +19981 Rpl37a MGI:MGI:98068|Ensembl:ENSMUSG00000046330|Vega:OTTMUSG00000061689 +19982 Rpl36a MGI:MGI:1201789|Ensembl:ENSMUSG00000079435|Vega:OTTMUSG00000019345 +19988 Rpl6 MGI:MGI:108057|Ensembl:ENSMUSG00000029614|Vega:OTTMUSG00000026261 +19989 Rpl7 MGI:MGI:98073|Ensembl:ENSMUSG00000043716|Vega:OTTMUSG00000016936 +20005 Rpl9 MGI:MGI:1298373|Ensembl:ENSMUSG00000047215|Vega:OTTMUSG00000028344 +20014 Rpn2 MGI:MGI:98085|Ensembl:ENSMUSG00000027642|Vega:OTTMUSG00000016167 +20015 Rpn2-rs1 MGI:MGI:107886 +20016 Polr1c MGI:MGI:103288|Ensembl:ENSMUSG00000067148|Vega:OTTMUSG00000028872 +20017 Polr1b MGI:MGI:108014|Ensembl:ENSMUSG00000027395|Vega:OTTMUSG00000015413 +20018 Polr1d MGI:MGI:108403|Ensembl:ENSMUSG00000029642|Vega:OTTMUSG00000024630 +20019 Polr1a MGI:MGI:1096397|Ensembl:ENSMUSG00000049553|Vega:OTTMUSG00000057916 +20020 Polr2a MGI:MGI:98086|Ensembl:ENSMUSG00000005198|Vega:OTTMUSG00000006003 +20021 Polr2c MGI:MGI:109299|Ensembl:ENSMUSG00000031783|Vega:OTTMUSG00000061706 +20022 Polr2j MGI:MGI:109582|Ensembl:ENSMUSG00000039771|Vega:OTTMUSG00000025440 +20024 Sub1 MGI:MGI:104811|Ensembl:ENSMUSG00000022205|Vega:OTTMUSG00000023586 +20028 Pdc MGI:MGI:98090|Ensembl:ENSMUSG00000006007|Vega:OTTMUSG00000049379 +20042 Rps12 MGI:MGI:98105|Ensembl:ENSMUSG00000061983 +20044 Rps14 MGI:MGI:98107|Ensembl:ENSMUSG00000024608|Vega:OTTMUSG00000031382 +20054 Rps15 MGI:MGI:98117|Ensembl:ENSMUSG00000063457|Vega:OTTMUSG00000000015 +20055 Rps16 MGI:MGI:98118|Ensembl:ENSMUSG00000037563|Vega:OTTMUSG00000022980 +20068 Rps17 MGI:MGI:1309526|Ensembl:ENSMUSG00000061787|Vega:OTTMUSG00000022965 +20084 Rps18 MGI:MGI:98146|Ensembl:ENSMUSG00000008668|Vega:OTTMUSG00000037085 +20085 Rps19 MGI:MGI:1333780|Ensembl:ENSMUSG00000040952|Vega:OTTMUSG00000022935 +20088 Rps24 MGI:MGI:98147|Ensembl:ENSMUSG00000025290 +20090 Rps29 MGI:MGI:107681|Ensembl:ENSMUSG00000034892|Vega:OTTMUSG00000023728 +20091 Rps3a1 MGI:MGI:1202063|Ensembl:ENSMUSG00000028081|Vega:OTTMUSG00000035152 +20102 Rps4x MGI:MGI:98158|Ensembl:ENSMUSG00000031320|Vega:OTTMUSG00000018303 +20103 Rps5 MGI:MGI:1097682|Ensembl:ENSMUSG00000012848|Vega:OTTMUSG00000023212 +20104 Rps6 MGI:MGI:98159|Ensembl:ENSMUSG00000028495|Vega:OTTMUSG00000007781 +20111 Rps6ka1 MGI:MGI:104558|Ensembl:ENSMUSG00000003644|Vega:OTTMUSG00000009632 +20112 Rps6ka2 MGI:MGI:1342290|Ensembl:ENSMUSG00000023809 +20115 Rps7 MGI:MGI:1333818|Ensembl:ENSMUSG00000061477 +20116 Rps8 MGI:MGI:98166|Ensembl:ENSMUSG00000047675|Vega:OTTMUSG00000009917 +20128 Trim30a MGI:MGI:98178|Ensembl:ENSMUSG00000030921|Vega:OTTMUSG00000019192 +20129 Rptn MGI:MGI:1099055|Ensembl:ENSMUSG00000041984|Vega:OTTMUSG00000043593 +20130 Rras MGI:MGI:98179|Ensembl:ENSMUSG00000038387|Vega:OTTMUSG00000022547 +20132 Rrh MGI:MGI:1097709|Ensembl:ENSMUSG00000028012|Vega:OTTMUSG00000054633 +20133 Rrm1 MGI:MGI:98180|Ensembl:ENSMUSG00000030978|Vega:OTTMUSG00000060506 +20135 Rrm2 MGI:MGI:98181|Ensembl:ENSMUSG00000020649|Vega:OTTMUSG00000027512 +20146 rs MGI:MGI:98188 +20147 Rs1 MGI:MGI:1336189|Ensembl:ENSMUSG00000031293|Vega:OTTMUSG00000019592 +20148 Dhrs3 MGI:MGI:1315215|Ensembl:ENSMUSG00000066026|Vega:OTTMUSG00000010749 +20150 rsm1 MGI:MGI:98189 +20163 Rsu1 MGI:MGI:103040|Ensembl:ENSMUSG00000026727|Vega:OTTMUSG00000011230 +20164 Opn1lw MGI:MGI:98202 +20166 Rtkn MGI:MGI:107371|Ensembl:ENSMUSG00000034930|Vega:OTTMUSG00000026967 +20167 Rtn2 MGI:MGI:107612|Ensembl:ENSMUSG00000030401|Vega:OTTMUSG00000058967 +20168 Rtn3 MGI:MGI:1339970|Ensembl:ENSMUSG00000024758 +20170 Hps6 MGI:MGI:2181763|Ensembl:ENSMUSG00000074811 +20173 ruf MGI:MGI:98207 +20174 Ruvbl2 MGI:MGI:1342299|Ensembl:ENSMUSG00000003868|Vega:OTTMUSG00000023863 +20181 Rxra MGI:MGI:98214|Ensembl:ENSMUSG00000015846|Vega:OTTMUSG00000012047 +20182 Rxrb MGI:MGI:98215|Ensembl:ENSMUSG00000039656|Vega:OTTMUSG00000037107 +20183 Rxrg MGI:MGI:98216|Ensembl:ENSMUSG00000015843|Vega:OTTMUSG00000022560 +20184 Uimc1 MGI:MGI:103185|Ensembl:ENSMUSG00000025878|Vega:OTTMUSG00000032667 +20185 Ncor1 MGI:MGI:1349717|Ensembl:ENSMUSG00000018501|Vega:OTTMUSG00000005855 +20186 Nr1h4 MGI:MGI:1352464|Ensembl:ENSMUSG00000047638|Vega:OTTMUSG00000022710 +20187 Ryk MGI:MGI:101766|Ensembl:ENSMUSG00000032547|Vega:OTTMUSG00000041987 +20190 Ryr1 MGI:MGI:99659|Ensembl:ENSMUSG00000030592|Vega:OTTMUSG00000059211 +20191 Ryr2 MGI:MGI:99685|Ensembl:ENSMUSG00000021313 +20192 Ryr3 MGI:MGI:99684|Ensembl:ENSMUSG00000057378|Vega:OTTMUSG00000015132 +20193 S100a1 MGI:MGI:1338917|Ensembl:ENSMUSG00000044080|Vega:OTTMUSG00000022107 +20194 S100a10 MGI:MGI:1339468|Ensembl:ENSMUSG00000041959|Vega:OTTMUSG00000022124 +20195 S100a11 MGI:MGI:1338798|Ensembl:ENSMUSG00000027907|Vega:OTTMUSG00000022126 +20196 S100a13 MGI:MGI:109581|Ensembl:ENSMUSG00000042312|Vega:OTTMUSG00000022110 +20197 S100a3 MGI:MGI:1338849|Ensembl:ENSMUSG00000001021|Vega:OTTMUSG00000052753 +20198 S100a4 MGI:MGI:1330282|Ensembl:ENSMUSG00000001020|Vega:OTTMUSG00000022114 +20199 S100a5 MGI:MGI:1338915|Ensembl:ENSMUSG00000001023|Vega:OTTMUSG00000022120 +20200 S100a6 MGI:MGI:1339467|Ensembl:ENSMUSG00000001025|Vega:OTTMUSG00000052755 +20201 S100a8 MGI:MGI:88244|Ensembl:ENSMUSG00000056054|Vega:OTTMUSG00000052758 +20202 S100a9 MGI:MGI:1338947|Ensembl:ENSMUSG00000056071|Vega:OTTMUSG00000026669 +20203 S100b MGI:MGI:98217|Ensembl:ENSMUSG00000033208|Vega:OTTMUSG00000020277 +20204 Prrx2 MGI:MGI:98218|Ensembl:ENSMUSG00000039476|Vega:OTTMUSG00000011872 +20207 Saa-ps MGI:MGI:108518 +20208 Saa1 MGI:MGI:98221|Ensembl:ENSMUSG00000074115|Vega:OTTMUSG00000033491 +20209 Saa2 MGI:MGI:98222|Ensembl:ENSMUSG00000057465|Vega:OTTMUSG00000060226 +20210 Saa3 MGI:MGI:98223|Ensembl:ENSMUSG00000040026|Vega:OTTMUSG00000060224 +20211 Saa4 MGI:MGI:98224|Ensembl:ENSMUSG00000040017|Vega:OTTMUSG00000058658 +20215 Sag MGI:MGI:98227|Ensembl:ENSMUSG00000056055|Vega:OTTMUSG00000021826 +20216 Acsm3 MGI:MGI:99538|Ensembl:ENSMUSG00000030935|Vega:OTTMUSG00000025655 +20217 sal MGI:MGI:98228 +20218 Khdrbs1 MGI:MGI:893579|Ensembl:ENSMUSG00000028790|Vega:OTTMUSG00000009514 +20219 Apcs MGI:MGI:98229|Ensembl:ENSMUSG00000026542|Vega:OTTMUSG00000050160 +20220 Sap18 MGI:MGI:1277978|Ensembl:ENSMUSG00000021963|Vega:OTTMUSG00000022377 +20222 Sf3a2 MGI:MGI:104912|Ensembl:ENSMUSG00000020211|Vega:OTTMUSG00000032875 +20223 sar MGI:MGI:107680 +20224 Sar1a MGI:MGI:98230|Ensembl:ENSMUSG00000020088 +20226 Sars MGI:MGI:102809|Ensembl:ENSMUSG00000068739|Vega:OTTMUSG00000007261 +20227 Sart1 MGI:MGI:1309453|Ensembl:ENSMUSG00000039148 +20229 Sat1 MGI:MGI:98233|Ensembl:ENSMUSG00000025283|Vega:OTTMUSG00000019352 +20230 Satb1 MGI:MGI:105084|Ensembl:ENSMUSG00000023927|Vega:OTTMUSG00000033991 +20231 Nkx1-2 MGI:MGI:104806|Ensembl:ENSMUSG00000048528|Vega:OTTMUSG00000036708 +20233 sb MGI:MGI:98234 +20234 Sbp MGI:MGI:106021|Ensembl:ENSMUSG00000024128|Vega:OTTMUSG00000043616 +20237 sc MGI:MGI:98235 +20238 Atxn1 MGI:MGI:104783|Ensembl:ENSMUSG00000046876 +20239 Atxn2 MGI:MGI:1277223|Ensembl:ENSMUSG00000042605|Vega:OTTMUSG00000034728 +20242 scb MGI:MGI:98237 +20248 Serpinb3a MGI:MGI:3573933|Ensembl:ENSMUSG00000044594|Vega:OTTMUSG00000021000 +20249 Scd1 MGI:MGI:98239|Ensembl:ENSMUSG00000037071 +20250 Scd2 MGI:MGI:98240|Ensembl:ENSMUSG00000025203 +20254 Scg2 MGI:MGI:103033|Ensembl:ENSMUSG00000050711|Vega:OTTMUSG00000047863 +20255 Scg3 MGI:MGI:103032|Ensembl:ENSMUSG00000032181|Vega:OTTMUSG00000062792 +20256 Clec11a MGI:MGI:1298219|Ensembl:ENSMUSG00000004473|Vega:OTTMUSG00000058327 +20257 Stmn2 MGI:MGI:98241|Ensembl:ENSMUSG00000027500|Vega:OTTMUSG00000051383 +20258 sch MGI:MGI:98242 +20259 Scin MGI:MGI:1306794|Ensembl:ENSMUSG00000002565|Vega:OTTMUSG00000027556 +20262 Stmn3 MGI:MGI:1277137|Ensembl:ENSMUSG00000027581|Vega:OTTMUSG00000016652 +20264 Scn10a MGI:MGI:108029|Ensembl:ENSMUSG00000034533|Vega:OTTMUSG00000062993 +20265 Scn1a MGI:MGI:98246|Ensembl:ENSMUSG00000064329|Vega:OTTMUSG00000013102 +20266 Scn1b MGI:MGI:98247|Ensembl:ENSMUSG00000019194|Vega:OTTMUSG00000045672 +20269 Scn3a MGI:MGI:98249|Ensembl:ENSMUSG00000057182|Vega:OTTMUSG00000012887 +20271 Scn5a MGI:MGI:98251|Ensembl:ENSMUSG00000032511|Vega:OTTMUSG00000031832 +20272 Scn7a MGI:MGI:102965|Ensembl:ENSMUSG00000034810|Vega:OTTMUSG00000013100 +20273 Scn8a MGI:MGI:103169|Ensembl:ENSMUSG00000023033|Vega:OTTMUSG00000055611 +20274 Scn9a MGI:MGI:107636|Ensembl:ENSMUSG00000075316|Vega:OTTMUSG00000013103 +20276 Scnn1a MGI:MGI:101782|Ensembl:ENSMUSG00000030340|Vega:OTTMUSG00000038566 +20277 Scnn1b MGI:MGI:104696|Ensembl:ENSMUSG00000030873|Vega:OTTMUSG00000058100 +20278 Scnn1g MGI:MGI:104695|Ensembl:ENSMUSG00000000216|Vega:OTTMUSG00000024632 +20280 Scp2 MGI:MGI:98254|Ensembl:ENSMUSG00000028603|Vega:OTTMUSG00000009429 +20281 Scp2-ps1 MGI:MGI:98255 +20282 Scp2-ps2 MGI:MGI:107679 +20284 Scrg1 MGI:MGI:1328308|Ensembl:ENSMUSG00000031610|Vega:OTTMUSG00000060715 +20286 Zc3h7b MGI:MGI:1328310|Ensembl:ENSMUSG00000022390 +20287 Sct MGI:MGI:99466|Ensembl:ENSMUSG00000038580|Vega:OTTMUSG00000060259 +20288 Msr1 MGI:MGI:98257|Ensembl:ENSMUSG00000025044|Vega:OTTMUSG00000061057 +20289 Scx MGI:MGI:102934|Ensembl:ENSMUSG00000034161 +20290 Ccl1 MGI:MGI:98258|Ensembl:ENSMUSG00000020702|Vega:OTTMUSG00000000926 +20292 Ccl11 MGI:MGI:103576|Ensembl:ENSMUSG00000020676|Vega:OTTMUSG00000000860 +20293 Ccl12 MGI:MGI:108224|Ensembl:ENSMUSG00000035352|Vega:OTTMUSG00000000861 +20294 Ccl16-ps MGI:MGI:1341246 +20295 Ccl17 MGI:MGI:1329039|Ensembl:ENSMUSG00000031780|Vega:OTTMUSG00000061705 +20296 Ccl2 MGI:MGI:98259|Ensembl:ENSMUSG00000035385|Vega:OTTMUSG00000000852 +20297 Ccl20 MGI:MGI:1329031|Ensembl:ENSMUSG00000026166|Vega:OTTMUSG00000016631 +20299 Ccl22 MGI:MGI:1306779|Ensembl:ENSMUSG00000031779|Vega:OTTMUSG00000016635 +20300 Ccl25 MGI:MGI:1099448|Ensembl:ENSMUSG00000023235|Vega:OTTMUSG00000022436 +20301 Ccl27a MGI:MGI:1343459|Ensembl:ENSMUSG00000073888|Vega:OTTMUSG00000006697 +20302 Ccl3 MGI:MGI:98260|Ensembl:ENSMUSG00000000982|Vega:OTTMUSG00000000991 +20303 Ccl4 MGI:MGI:98261|Ensembl:ENSMUSG00000018930|Vega:OTTMUSG00000000993 +20304 Ccl5 MGI:MGI:98262|Ensembl:ENSMUSG00000035042|Vega:OTTMUSG00000000992 +20305 Ccl6 MGI:MGI:98263|Ensembl:ENSMUSG00000018927|Vega:OTTMUSG00000000995 +20306 Ccl7 MGI:MGI:99512|Ensembl:ENSMUSG00000035373|Vega:OTTMUSG00000000856 +20307 Ccl8 MGI:MGI:101878|Ensembl:ENSMUSG00000009185|Vega:OTTMUSG00000000929 +20308 Ccl9 MGI:MGI:104533|Ensembl:ENSMUSG00000019122|Vega:OTTMUSG00000000998 +20309 Cxcl15 MGI:MGI:1339941|Ensembl:ENSMUSG00000029375|Vega:OTTMUSG00000055507 +20310 Cxcl2 MGI:MGI:1340094|Ensembl:ENSMUSG00000058427|Vega:OTTMUSG00000055510 +20311 Cxcl5 MGI:MGI:1096868|Ensembl:ENSMUSG00000029371|Vega:OTTMUSG00000055503 +20312 Cx3cl1 MGI:MGI:1097153|Ensembl:ENSMUSG00000031778|Vega:OTTMUSG00000029903 +20315 Cxcl12 MGI:MGI:103556|Ensembl:ENSMUSG00000061353|Vega:OTTMUSG00000022768 +20316 Sdf2 MGI:MGI:108019|Ensembl:ENSMUSG00000002064|Vega:OTTMUSG00000000094 +20317 Serpinf1 MGI:MGI:108080|Ensembl:ENSMUSG00000000753|Vega:OTTMUSG00000006203 +20318 Sdf4 MGI:MGI:108079|Ensembl:ENSMUSG00000029076|Vega:OTTMUSG00000010986 +20319 Sfrp2 MGI:MGI:108078|Ensembl:ENSMUSG00000027996|Vega:OTTMUSG00000021261 +20320 Nptn MGI:MGI:108077|Ensembl:ENSMUSG00000032336|Vega:OTTMUSG00000042067 +20321 Frrs1 MGI:MGI:108076|Ensembl:ENSMUSG00000033386|Vega:OTTMUSG00000054477 +20322 Sord MGI:MGI:98266|Ensembl:ENSMUSG00000027227|Vega:OTTMUSG00000015564 +20324 Cavin2 MGI:MGI:99513|Ensembl:ENSMUSG00000045954|Vega:OTTMUSG00000046712 +20329 sea MGI:MGI:98272 +20331 seb MGI:MGI:98274 +20333 Sec22b MGI:MGI:1338759|Ensembl:ENSMUSG00000027879|Vega:OTTMUSG00000028867 +20334 Sec23a MGI:MGI:1349635|Ensembl:ENSMUSG00000020986|Vega:OTTMUSG00000026430 +20335 Sec61g MGI:MGI:1202066|Ensembl:ENSMUSG00000078974|Vega:OTTMUSG00000005181 +20336 Exoc4 MGI:MGI:1096376|Ensembl:ENSMUSG00000029763|Vega:OTTMUSG00000014760 +20338 Sel1l MGI:MGI:1329016|Ensembl:ENSMUSG00000020964|Vega:OTTMUSG00000035560 +20339 Sele MGI:MGI:98278|Ensembl:ENSMUSG00000026582|Vega:OTTMUSG00000050836 +20340 Glg1 MGI:MGI:104967|Ensembl:ENSMUSG00000003316|Vega:OTTMUSG00000036006 +20341 Selenbp1 MGI:MGI:96825|Ensembl:ENSMUSG00000068874|Vega:OTTMUSG00000019656 +20342 Selenbp2 MGI:MGI:104859|Ensembl:ENSMUSG00000068877|Vega:OTTMUSG00000019564 +20343 Sell MGI:MGI:98279|Ensembl:ENSMUSG00000026581|Vega:OTTMUSG00000050837 +20344 Selp MGI:MGI:98280|Ensembl:ENSMUSG00000026580|Vega:OTTMUSG00000034812 +20345 Selplg MGI:MGI:106689|Ensembl:ENSMUSG00000048163|Vega:OTTMUSG00000055395 +20346 Sema3a MGI:MGI:107558|Ensembl:ENSMUSG00000028883|Vega:OTTMUSG00000021298 +20347 Sema3b MGI:MGI:107561|Ensembl:ENSMUSG00000057969|Vega:OTTMUSG00000016526 +20348 Sema3c MGI:MGI:107557|Ensembl:ENSMUSG00000028780|Vega:OTTMUSG00000035305 +20349 Sema3e MGI:MGI:1340034|Ensembl:ENSMUSG00000063531|Vega:OTTMUSG00000029684 +20350 Sema3f MGI:MGI:1096347|Ensembl:ENSMUSG00000034684|Vega:OTTMUSG00000050787 +20351 Sema4a MGI:MGI:107560|Ensembl:ENSMUSG00000028064|Vega:OTTMUSG00000021258 +20352 Sema4b MGI:MGI:107559|Ensembl:ENSMUSG00000030539|Vega:OTTMUSG00000021122 +20353 Sema4c MGI:MGI:109252|Ensembl:ENSMUSG00000026121|Vega:OTTMUSG00000020876 +20354 Sema4d MGI:MGI:109244|Ensembl:ENSMUSG00000021451|Vega:OTTMUSG00000020953 +20355 Sema4f MGI:MGI:1340055|Ensembl:ENSMUSG00000000627|Vega:OTTMUSG00000021185 +20356 Sema5a MGI:MGI:107556|Ensembl:ENSMUSG00000022231 +20357 Sema5b MGI:MGI:107555|Ensembl:ENSMUSG00000052133|Vega:OTTMUSG00000027281 +20358 Sema6a MGI:MGI:1203727|Ensembl:ENSMUSG00000019647|Vega:OTTMUSG00000033972 +20359 Sema6b MGI:MGI:1202889|Ensembl:ENSMUSG00000001227 +20360 Sema6c MGI:MGI:1338032|Ensembl:ENSMUSG00000038777|Vega:OTTMUSG00000022286 +20361 Sema7a MGI:MGI:1306826|Ensembl:ENSMUSG00000038264|Vega:OTTMUSG00000063232 +20362 Sept8 MGI:MGI:894310|Ensembl:ENSMUSG00000018398|Vega:OTTMUSG00000005635 +20363 Selenop MGI:MGI:894288|Ensembl:ENSMUSG00000064373|Vega:OTTMUSG00000035135 +20364 Selenow MGI:MGI:1100878|Ensembl:ENSMUSG00000041571|Vega:OTTMUSG00000021063 +20365 Serf1 MGI:MGI:1337114|Ensembl:ENSMUSG00000021643|Vega:OTTMUSG00000032625 +20366 Gm4748 MGI:MGI:3822518 +20370 Sez6 MGI:MGI:104745|Ensembl:ENSMUSG00000000632|Vega:OTTMUSG00000000068 +20371 Foxp3 MGI:MGI:1891436|Ensembl:ENSMUSG00000039521|Vega:OTTMUSG00000016624 +20375 Spi1 MGI:MGI:98282|Ensembl:ENSMUSG00000002111|Vega:OTTMUSG00000014371 +20377 Sfrp1 MGI:MGI:892014|Ensembl:ENSMUSG00000031548|Vega:OTTMUSG00000021102 +20378 Frzb MGI:MGI:892032|Ensembl:ENSMUSG00000027004|Vega:OTTMUSG00000013372 +20379 Sfrp4 MGI:MGI:892010|Ensembl:ENSMUSG00000021319 +20382 Srsf2 MGI:MGI:98284|Ensembl:ENSMUSG00000034120|Vega:OTTMUSG00000003783 +20383 Srsf3 MGI:MGI:98285|Ensembl:ENSMUSG00000071172|Vega:OTTMUSG00000031658 +20384 Srsf5 MGI:MGI:98287|Ensembl:ENSMUSG00000021134|Vega:OTTMUSG00000021161 +20387 Sftpa1 MGI:MGI:109518|Ensembl:ENSMUSG00000021789|Vega:OTTMUSG00000035515 +20388 Sftpb MGI:MGI:109516|Ensembl:ENSMUSG00000056370|Vega:OTTMUSG00000044332 +20389 Sftpc MGI:MGI:109517|Ensembl:ENSMUSG00000022097 +20390 Sftpd MGI:MGI:109515|Ensembl:ENSMUSG00000021795 +20391 Sgca MGI:MGI:894698|Ensembl:ENSMUSG00000001508|Vega:OTTMUSG00000001503 +20392 Sgce MGI:MGI:1329042|Ensembl:ENSMUSG00000004631|Vega:OTTMUSG00000023184 +20393 Sgk1 MGI:MGI:1340062|Ensembl:ENSMUSG00000019970|Vega:OTTMUSG00000031274 +20394 Scg5 MGI:MGI:98289|Ensembl:ENSMUSG00000023236|Vega:OTTMUSG00000019161 +20397 Sgpl1 MGI:MGI:1261415|Ensembl:ENSMUSG00000020097|Vega:OTTMUSG00000031946 +20399 Sh2b1 MGI:MGI:1201407|Ensembl:ENSMUSG00000030733|Vega:OTTMUSG00000058215 +20400 Sh2d1a MGI:MGI:1328352|Ensembl:ENSMUSG00000005696|Vega:OTTMUSG00000017466 +20401 Sh3bp1 MGI:MGI:104603|Ensembl:ENSMUSG00000022436|Vega:OTTMUSG00000021739 +20402 Zfp106 MGI:MGI:1270153|Ensembl:ENSMUSG00000027288|Vega:OTTMUSG00000015618 +20403 Itsn2 MGI:MGI:1338049|Ensembl:ENSMUSG00000020640 +20404 Sh3gl2 MGI:MGI:700009|Ensembl:ENSMUSG00000028488|Vega:OTTMUSG00000007959 +20405 Sh3gl1 MGI:MGI:700010|Ensembl:ENSMUSG00000003200 +20406 Sh3d2c-ps1 MGI:MGI:1313300 +20408 Sh3gl3 MGI:MGI:700011|Ensembl:ENSMUSG00000030638|Vega:OTTMUSG00000042384 +20409 Ostf1 MGI:MGI:700012|Ensembl:ENSMUSG00000024725|Vega:OTTMUSG00000028671 +20410 Sorbs3 MGI:MGI:700013|Ensembl:ENSMUSG00000022091 +20411 Sorbs1 MGI:MGI:700014|Ensembl:ENSMUSG00000025006 +20415 Shbg MGI:MGI:98295|Ensembl:ENSMUSG00000005202|Vega:OTTMUSG00000005986 +20416 Shc1 MGI:MGI:98296|Ensembl:ENSMUSG00000042626|Vega:OTTMUSG00000022071 +20418 Shc3 MGI:MGI:106179|Ensembl:ENSMUSG00000021448 +20419 Shcbp1 MGI:MGI:1338802|Ensembl:ENSMUSG00000022322|Vega:OTTMUSG00000059763 +20420 Shd MGI:MGI:1099461|Ensembl:ENSMUSG00000039154 +20422 Sem1 MGI:MGI:109238|Ensembl:ENSMUSG00000042541|Vega:OTTMUSG00000024492 +20423 Shh MGI:MGI:98297|Ensembl:ENSMUSG00000002633|Vega:OTTMUSG00000021299 +20425 Shmt1 MGI:MGI:98299|Ensembl:ENSMUSG00000020534|Vega:OTTMUSG00000007760 +20427 shmy MGI:MGI:99514 +20428 sho MGI:MGI:98300 +20429 Shox2 MGI:MGI:1201673|Ensembl:ENSMUSG00000027833|Vega:OTTMUSG00000042120 +20430 Cyfip1 MGI:MGI:1338801|Ensembl:ENSMUSG00000030447|Vega:OTTMUSG00000037588 +20431 Pmel MGI:MGI:98301|Ensembl:ENSMUSG00000025359 +20435 Siah1-ps1 MGI:MGI:108066 +20437 Siah1a MGI:MGI:108064|Ensembl:ENSMUSG00000036840|Vega:OTTMUSG00000061427 +20438 Siah1b MGI:MGI:108063|Ensembl:ENSMUSG00000040749|Vega:OTTMUSG00000019519 +20439 Siah2 MGI:MGI:108062|Ensembl:ENSMUSG00000036432|Vega:OTTMUSG00000029497 +20440 St6gal1 MGI:MGI:108470|Ensembl:ENSMUSG00000022885|Vega:OTTMUSG00000025920 +20441 St3gal3 MGI:MGI:1316659|Ensembl:ENSMUSG00000028538|Vega:OTTMUSG00000008662 +20442 St3gal1 MGI:MGI:98304|Ensembl:ENSMUSG00000013846 +20443 St3gal4 MGI:MGI:1316743|Ensembl:ENSMUSG00000032038|Vega:OTTMUSG00000062940 +20444 St3gal2 MGI:MGI:99427|Ensembl:ENSMUSG00000031749|Vega:OTTMUSG00000031001 +20445 St6galnac1 MGI:MGI:1341826|Ensembl:ENSMUSG00000009588|Vega:OTTMUSG00000003789 +20446 St6galnac2 MGI:MGI:107553|Ensembl:ENSMUSG00000057286|Vega:OTTMUSG00000060264 +20447 St6galnac3 MGI:MGI:1341828|Ensembl:ENSMUSG00000052544|Vega:OTTMUSG00000053451 +20448 St6galnac4 MGI:MGI:1341894|Ensembl:ENSMUSG00000079442|Vega:OTTMUSG00000011982 +20449 St8sia1 MGI:MGI:106011|Ensembl:ENSMUSG00000030283|Vega:OTTMUSG00000022470 +20450 St8sia2 MGI:MGI:106020|Ensembl:ENSMUSG00000025789|Vega:OTTMUSG00000049840 +20451 St8sia3 MGI:MGI:106019|Ensembl:ENSMUSG00000056812|Vega:OTTMUSG00000028204 +20452 St8sia4 MGI:MGI:106018|Ensembl:ENSMUSG00000040710|Vega:OTTMUSG00000048753 +20454 St3gal5 MGI:MGI:1339963|Ensembl:ENSMUSG00000056091|Vega:OTTMUSG00000048445 +20455 Sif1 MGI:MGI:102693 +20459 Ptk6 MGI:MGI:99683|Ensembl:ENSMUSG00000038751|Vega:OTTMUSG00000016561 +20460 Stil MGI:MGI:107477|Ensembl:ENSMUSG00000028718|Vega:OTTMUSG00000008583 +20461 Gm14270 MGI:MGI:3649849 +20462 Tra2b MGI:MGI:106016|Ensembl:ENSMUSG00000022858|Vega:OTTMUSG00000035118 +20463 Cox7a2l MGI:MGI:106015|Ensembl:ENSMUSG00000024248 +20464 Sim1 MGI:MGI:98306|Ensembl:ENSMUSG00000019913 +20465 Sim2 MGI:MGI:98307|Ensembl:ENSMUSG00000062713 +20466 Sin3a MGI:MGI:107157|Ensembl:ENSMUSG00000042557|Vega:OTTMUSG00000036738 +20467 Sin3b MGI:MGI:107158|Ensembl:ENSMUSG00000031622|Vega:OTTMUSG00000062065 +20469 Sipa1 MGI:MGI:107576|Ensembl:ENSMUSG00000056917 +20471 Six1 MGI:MGI:102780|Ensembl:ENSMUSG00000051367|Vega:OTTMUSG00000040058 +20472 Six2 MGI:MGI:102778|Ensembl:ENSMUSG00000024134|Vega:OTTMUSG00000040063 +20473 Six3 MGI:MGI:102764|Ensembl:ENSMUSG00000038805|Vega:OTTMUSG00000040062 +20474 Six4 MGI:MGI:106034|Ensembl:ENSMUSG00000034460|Vega:OTTMUSG00000040060 +20475 Six5 MGI:MGI:106220|Ensembl:ENSMUSG00000040841|Vega:OTTMUSG00000040064 +20476 Six6 MGI:MGI:1341840|Ensembl:ENSMUSG00000021099|Vega:OTTMUSG00000040057 +20479 Vps4b MGI:MGI:1100499|Ensembl:ENSMUSG00000009907|Vega:OTTMUSG00000021646 +20480 Clpb MGI:MGI:1100517|Ensembl:ENSMUSG00000001829|Vega:OTTMUSG00000022234 +20481 Ski MGI:MGI:98310|Ensembl:ENSMUSG00000029050|Vega:OTTMUSG00000010598 +20482 Skil MGI:MGI:106203|Ensembl:ENSMUSG00000027660|Vega:OTTMUSG00000027813 +20486 skt MGI:MGI:98314 +20491 Sla MGI:MGI:104295|Ensembl:ENSMUSG00000022372|Vega:OTTMUSG00000035627 +20492 Slbp MGI:MGI:108402|Ensembl:ENSMUSG00000004642|Vega:OTTMUSG00000025101 +20493 Slc10a1 MGI:MGI:97379|Ensembl:ENSMUSG00000021135 +20494 Slc10a2 MGI:MGI:1201406|Ensembl:ENSMUSG00000023073|Vega:OTTMUSG00000059770 +20495 Slc12a1 MGI:MGI:103150|Ensembl:ENSMUSG00000027202|Vega:OTTMUSG00000015338 +20496 Slc12a2 MGI:MGI:101924|Ensembl:ENSMUSG00000024597 +20497 Slc12a3 MGI:MGI:108114|Ensembl:ENSMUSG00000031766|Vega:OTTMUSG00000061636 +20498 Slc12a4 MGI:MGI:1309465|Ensembl:ENSMUSG00000017765|Vega:OTTMUSG00000031019 +20499 Slc12a7 MGI:MGI:1342283|Ensembl:ENSMUSG00000017756 +20500 Slc13a2 MGI:MGI:1276558|Ensembl:ENSMUSG00000001095|Vega:OTTMUSG00000000151 +20501 Slc16a1 MGI:MGI:106013|Ensembl:ENSMUSG00000032902|Vega:OTTMUSG00000022475 +20502 Slc16a2 MGI:MGI:1203732|Ensembl:ENSMUSG00000033965|Vega:OTTMUSG00000018361 +20503 Slc16a7 MGI:MGI:1330284|Ensembl:ENSMUSG00000020102|Vega:OTTMUSG00000060295 +20504 Slc17a1 MGI:MGI:103209|Ensembl:ENSMUSG00000021335|Vega:OTTMUSG00000000728 +20505 Slc34a1 MGI:MGI:1345284|Ensembl:ENSMUSG00000021490 +20508 Slc18a3 MGI:MGI:1101061|Ensembl:ENSMUSG00000100241|Vega:OTTMUSG00000049703 +20509 Slc19a1 MGI:MGI:103182|Ensembl:ENSMUSG00000001436|Vega:OTTMUSG00000033598 +20510 Slc1a1 MGI:MGI:105083|Ensembl:ENSMUSG00000024935|Vega:OTTMUSG00000033893 +20511 Slc1a2 MGI:MGI:101931|Ensembl:ENSMUSG00000005089|Vega:OTTMUSG00000014848 +20512 Slc1a3 MGI:MGI:99917|Ensembl:ENSMUSG00000005360|Vega:OTTMUSG00000032639 +20513 Slc1a6 MGI:MGI:1096331|Ensembl:ENSMUSG00000005357 +20514 Slc1a5 MGI:MGI:105305|Ensembl:ENSMUSG00000001918|Vega:OTTMUSG00000022239 +20515 Slc20a1 MGI:MGI:108392|Ensembl:ENSMUSG00000027397|Vega:OTTMUSG00000015425 +20516 Slc20a2 MGI:MGI:97851|Ensembl:ENSMUSG00000037656|Vega:OTTMUSG00000060889 +20517 Slc22a1 MGI:MGI:108111|Ensembl:ENSMUSG00000023829 +20518 Slc22a2 MGI:MGI:1335072|Ensembl:ENSMUSG00000040966 +20519 Slc22a3 MGI:MGI:1333817|Ensembl:ENSMUSG00000023828 +20520 Slc22a5 MGI:MGI:1329012|Ensembl:ENSMUSG00000018900|Vega:OTTMUSG00000005649 +20521 Slc22a12 MGI:MGI:1195269|Ensembl:ENSMUSG00000061742|Vega:OTTMUSG00000018619 +20522 Slc23a1 MGI:MGI:1341903|Ensembl:ENSMUSG00000024354|Vega:OTTMUSG00000023952 +20523 Slc25a14 MGI:MGI:1330823|Ensembl:ENSMUSG00000031105|Vega:OTTMUSG00000017567 +20524 Slc25a17 MGI:MGI:1342248|Ensembl:ENSMUSG00000022404 +20525 Slc2a1 MGI:MGI:95755|Ensembl:ENSMUSG00000028645|Vega:OTTMUSG00000008836 +20526 Slc2a2 MGI:MGI:1095438|Ensembl:ENSMUSG00000027690|Vega:OTTMUSG00000035916 +20527 Slc2a3 MGI:MGI:95757|Ensembl:ENSMUSG00000003153|Vega:OTTMUSG00000036005 +20528 Slc2a4 MGI:MGI:95758|Ensembl:ENSMUSG00000018566|Vega:OTTMUSG00000006028 +20529 Slc31a1 MGI:MGI:1333843|Ensembl:ENSMUSG00000066150|Vega:OTTMUSG00000001231 +20530 Slc31a2 MGI:MGI:1333844|Ensembl:ENSMUSG00000066152|Vega:OTTMUSG00000000311 +20531 Slc34a2 MGI:MGI:1342284|Ensembl:ENSMUSG00000029188|Vega:OTTMUSG00000026277 +20532 Slc3a1 MGI:MGI:1195264|Ensembl:ENSMUSG00000024131 +20533 Slc4a1 MGI:MGI:109393|Ensembl:ENSMUSG00000006574|Vega:OTTMUSG00000002767 +20534 Slc4a1ap MGI:MGI:1196608|Ensembl:ENSMUSG00000029141|Vega:OTTMUSG00000028249 +20535 Slc4a2 MGI:MGI:109351|Ensembl:ENSMUSG00000028962|Vega:OTTMUSG00000024167 +20536 Slc4a3 MGI:MGI:109350|Ensembl:ENSMUSG00000006576|Vega:OTTMUSG00000019426 +20537 Slc5a1 MGI:MGI:107678|Ensembl:ENSMUSG00000011034|Vega:OTTMUSG00000027971 +20538 Slc6a2 MGI:MGI:1270850|Ensembl:ENSMUSG00000055368|Vega:OTTMUSG00000061538 +20539 Slc7a5 MGI:MGI:1298205|Ensembl:ENSMUSG00000040010|Vega:OTTMUSG00000043045 +20540 Slc7a7 MGI:MGI:1337120|Ensembl:ENSMUSG00000000958|Vega:OTTMUSG00000053898 +20541 Slc8a1 MGI:MGI:107956|Ensembl:ENSMUSG00000054640 +20544 Slc9a1 MGI:MGI:102462|Ensembl:ENSMUSG00000028854|Vega:OTTMUSG00000011153 +20555 Slfn1 MGI:MGI:1313259|Ensembl:ENSMUSG00000078763|Vega:OTTMUSG00000000916 +20556 Slfn2 MGI:MGI:1313258|Ensembl:ENSMUSG00000072620|Vega:OTTMUSG00000000918 +20557 Slfn3 MGI:MGI:1329005|Ensembl:ENSMUSG00000018986|Vega:OTTMUSG00000000919 +20558 Slfn4 MGI:MGI:1329010|Ensembl:ENSMUSG00000000204|Vega:OTTMUSG00000000920 +20562 Slit1 MGI:MGI:1315203|Ensembl:ENSMUSG00000025020|Vega:OTTMUSG00000036377 +20563 Slit2 MGI:MGI:1315205|Ensembl:ENSMUSG00000031558|Vega:OTTMUSG00000037422 +20564 Slit3 MGI:MGI:1315202|Ensembl:ENSMUSG00000056427|Vega:OTTMUSG00000005411 +20565 sll1 MGI:MGI:98318 +20566 sll2 MGI:MGI:98319 +20568 Slpi MGI:MGI:109297|Ensembl:ENSMUSG00000017002|Vega:OTTMUSG00000001167 +20583 Snai2 MGI:MGI:1096393|Ensembl:ENSMUSG00000022676 +20585 Hltf MGI:MGI:1196437|Ensembl:ENSMUSG00000002428|Vega:OTTMUSG00000026001 +20586 Smarca4 MGI:MGI:88192|Ensembl:ENSMUSG00000032187|Vega:OTTMUSG00000037140 +20587 Smarcb1 MGI:MGI:1328366|Ensembl:ENSMUSG00000000902|Vega:OTTMUSG00000031849 +20588 Smarcc1 MGI:MGI:1203524|Ensembl:ENSMUSG00000032481|Vega:OTTMUSG00000021083 +20589 Ighmbp2 MGI:MGI:99954|Ensembl:ENSMUSG00000024831|Vega:OTTMUSG00000028273 +20590 smc MGI:MGI:98322 +20591 Kdm5c MGI:MGI:99781|Ensembl:ENSMUSG00000025332|Vega:OTTMUSG00000017219 +20592 Kdm5d MGI:MGI:99780|Ensembl:ENSMUSG00000056673|Vega:OTTMUSG00000045277 +20595 Smn1 MGI:MGI:109257|Ensembl:ENSMUSG00000021645|Vega:OTTMUSG00000033496 +20597 Smpd1 MGI:MGI:98325|Ensembl:ENSMUSG00000037049|Vega:OTTMUSG00000060466 +20598 Smpd2 MGI:MGI:1278330|Ensembl:ENSMUSG00000019822|Vega:OTTMUSG00000030684 +20599 Smr3a MGI:MGI:102763|Ensembl:ENSMUSG00000029280|Vega:OTTMUSG00000049458 +20600 Smr2 MGI:MGI:102762|Ensembl:ENSMUSG00000029281|Vega:OTTMUSG00000055376 +20602 Ncor2 MGI:MGI:1337080|Ensembl:ENSMUSG00000029478|Vega:OTTMUSG00000017150 +20603 Sms MGI:MGI:109490|Ensembl:ENSMUSG00000071708|Vega:OTTMUSG00000019398 +20604 Sst MGI:MGI:98326|Ensembl:ENSMUSG00000004366 +20605 Sstr1 MGI:MGI:98327|Ensembl:ENSMUSG00000035431|Vega:OTTMUSG00000037022 +20606 Sstr2 MGI:MGI:98328|Ensembl:ENSMUSG00000047904|Vega:OTTMUSG00000003400 +20607 Sstr3 MGI:MGI:98329|Ensembl:ENSMUSG00000044933 +20608 Sstr4 MGI:MGI:105372|Ensembl:ENSMUSG00000037014|Vega:OTTMUSG00000015711 +20609 Sstr5 MGI:MGI:894282|Ensembl:ENSMUSG00000050824 +20610 Sumo3 MGI:MGI:1336201|Ensembl:ENSMUSG00000020265|Vega:OTTMUSG00000020927 +20611 Ssty1 MGI:MGI:1314663|Ensembl:ENSMUSG00000095267|Vega:OTTMUSG00000049726 +20612 Siglec1 MGI:MGI:99668|Ensembl:ENSMUSG00000027322|Vega:OTTMUSG00000015684 +20613 Snai1 MGI:MGI:98330|Ensembl:ENSMUSG00000042821|Vega:OTTMUSG00000001149 +20614 Snap25 MGI:MGI:98331|Ensembl:ENSMUSG00000027273|Vega:OTTMUSG00000015556 +20615 Snapin MGI:MGI:1333745|Ensembl:ENSMUSG00000001018|Vega:OTTMUSG00000022106 +20616 Snap91 MGI:MGI:109132|Ensembl:ENSMUSG00000033419|Vega:OTTMUSG00000045050 +20617 Snca MGI:MGI:1277151|Ensembl:ENSMUSG00000025889|Vega:OTTMUSG00000057624 +20618 Sncg MGI:MGI:1298397|Ensembl:ENSMUSG00000023064|Vega:OTTMUSG00000034011 +20619 Snap23 MGI:MGI:109356|Ensembl:ENSMUSG00000027287|Vega:OTTMUSG00000015619 +20620 Plk2 MGI:MGI:1099790|Ensembl:ENSMUSG00000021701 +20621 Snn MGI:MGI:1276549|Ensembl:ENSMUSG00000037972 +20622 sno MGI:MGI:98332 +20623 Snrk MGI:MGI:108104|Ensembl:ENSMUSG00000038145|Vega:OTTMUSG00000027423 +20624 Eftud2 MGI:MGI:1336880|Ensembl:ENSMUSG00000020929|Vega:OTTMUSG00000003085 +20630 Snrpc MGI:MGI:109489|Ensembl:ENSMUSG00000024217|Vega:OTTMUSG00000023175 +20631 Snrp1c-ps1 MGI:MGI:109488 +20632 Snrp1c-ps2 MGI:MGI:109487 +20637 Snrnp70 MGI:MGI:98341|Ensembl:ENSMUSG00000063511|Vega:OTTMUSG00000058338 +20638 Snrpb MGI:MGI:98342|Ensembl:ENSMUSG00000027404|Vega:OTTMUSG00000015496 +20639 Snrpb2 MGI:MGI:104805|Ensembl:ENSMUSG00000008333|Vega:OTTMUSG00000015607 +20641 Snrpd1 MGI:MGI:98344|Ensembl:ENSMUSG00000002477 +20643 Snrpe MGI:MGI:98346|Ensembl:ENSMUSG00000090553|Vega:OTTMUSG00000035312 +20646 Snrpn MGI:MGI:98347|Ensembl:ENSMUSG00000102252|Vega:OTTMUSG00000042349 +20648 Snta1 MGI:MGI:101772|Ensembl:ENSMUSG00000027488|Vega:OTTMUSG00000015793 +20649 Sntb1 MGI:MGI:101781|Ensembl:ENSMUSG00000060429|Vega:OTTMUSG00000023696 +20650 Sntb2 MGI:MGI:101771|Ensembl:ENSMUSG00000041308|Vega:OTTMUSG00000061930 +20652 Soat1 MGI:MGI:104665|Ensembl:ENSMUSG00000026600|Vega:OTTMUSG00000049652 +20654 soc MGI:MGI:98350 +20655 Sod1 MGI:MGI:98351|Ensembl:ENSMUSG00000022982 +20656 Sod2 MGI:MGI:98352|Ensembl:ENSMUSG00000006818 +20657 Sod3 MGI:MGI:103181|Ensembl:ENSMUSG00000072941|Vega:OTTMUSG00000054570 +20658 Son MGI:MGI:98353|Ensembl:ENSMUSG00000022961|Vega:OTTMUSG00000028340 +20659 soo MGI:MGI:1097155 +20660 Sorl1 MGI:MGI:1202296|Ensembl:ENSMUSG00000049313|Vega:OTTMUSG00000031794 +20661 Sort1 MGI:MGI:1338015|Ensembl:ENSMUSG00000068747|Vega:OTTMUSG00000007304 +20662 Sos1 MGI:MGI:98354|Ensembl:ENSMUSG00000024241 +20663 Sos2 MGI:MGI:98355|Ensembl:ENSMUSG00000034801|Vega:OTTMUSG00000044373 +20664 Sox1 MGI:MGI:98357|Ensembl:ENSMUSG00000096014|Vega:OTTMUSG00000042315 +20665 Sox10 MGI:MGI:98358|Ensembl:ENSMUSG00000033006 +20666 Sox11 MGI:MGI:98359|Ensembl:ENSMUSG00000063632|Vega:OTTMUSG00000021163 +20667 Sox12 MGI:MGI:98360|Ensembl:ENSMUSG00000051817|Vega:OTTMUSG00000015843 +20668 Sox13 MGI:MGI:98361|Ensembl:ENSMUSG00000070643|Vega:OTTMUSG00000026807 +20669 Sox14 MGI:MGI:98362|Ensembl:ENSMUSG00000053747|Vega:OTTMUSG00000044377 +20670 Sox15 MGI:MGI:98363|Ensembl:ENSMUSG00000041287|Vega:OTTMUSG00000005991 +20671 Sox17 MGI:MGI:107543|Ensembl:ENSMUSG00000025902|Vega:OTTMUSG00000050014 +20672 Sox18 MGI:MGI:103559|Ensembl:ENSMUSG00000046470|Vega:OTTMUSG00000016810 +20673 Sox19 MGI:MGI:1097162 +20674 Sox2 MGI:MGI:98364|Ensembl:ENSMUSG00000074637|Vega:OTTMUSG00000021249 +20675 Sox3 MGI:MGI:98365|Ensembl:ENSMUSG00000045179|Vega:OTTMUSG00000017611 +20677 Sox4 MGI:MGI:98366|Ensembl:ENSMUSG00000076431|Vega:OTTMUSG00000000729 +20678 Sox5 MGI:MGI:98367|Ensembl:ENSMUSG00000041540|Vega:OTTMUSG00000025246 +20679 Sox6 MGI:MGI:98368|Ensembl:ENSMUSG00000051910|Vega:OTTMUSG00000058723 +20680 Sox7 MGI:MGI:98369|Ensembl:ENSMUSG00000063060 +20681 Sox8 MGI:MGI:98370|Ensembl:ENSMUSG00000024176|Vega:OTTMUSG00000038220 +20682 Sox9 MGI:MGI:98371|Ensembl:ENSMUSG00000000567|Vega:OTTMUSG00000003313 +20683 Sp1 MGI:MGI:98372|Ensembl:ENSMUSG00000001280|Vega:OTTMUSG00000035159 +20684 Sp100 MGI:MGI:109561|Ensembl:ENSMUSG00000026222|Vega:OTTMUSG00000030061 +20685 Sp100-rs1 MGI:MGI:1097710 +20686 Spa17 MGI:MGI:1333778|Ensembl:ENSMUSG00000001948|Vega:OTTMUSG00000063101 +20687 Sp3 MGI:MGI:1277166|Ensembl:ENSMUSG00000027109|Vega:OTTMUSG00000013207 +20688 Sp4 MGI:MGI:107595|Ensembl:ENSMUSG00000025323 +20689 Sall3 MGI:MGI:109295|Ensembl:ENSMUSG00000024565 +20690 Spam1 MGI:MGI:109335|Ensembl:ENSMUSG00000029682|Vega:OTTMUSG00000056003 +20691 Span MGI:MGI:102786 +20692 Sparc MGI:MGI:98373|Ensembl:ENSMUSG00000018593|Vega:OTTMUSG00000005692 +20693 spc MGI:MGI:98374 +20698 Sphk1 MGI:MGI:1316649|Ensembl:ENSMUSG00000061878|Vega:OTTMUSG00000003900 +20700 Serpina1a MGI:MGI:891971|Ensembl:ENSMUSG00000066366|Vega:OTTMUSG00000023942 +20701 Serpina1b MGI:MGI:891970|Ensembl:ENSMUSG00000071178|Vega:OTTMUSG00000035410 +20702 Serpina1c MGI:MGI:891969|Ensembl:ENSMUSG00000079015|Vega:OTTMUSG00000023935 +20703 Serpina1d MGI:MGI:891968|Ensembl:ENSMUSG00000071177|Vega:OTTMUSG00000027640 +20704 Serpina1e MGI:MGI:891967|Ensembl:ENSMUSG00000072849|Vega:OTTMUSG00000027635 +20706 Serpinb9b MGI:MGI:894668|Ensembl:ENSMUSG00000021403|Vega:OTTMUSG00000000699 +20707 Serpinb9c MGI:MGI:894669|Ensembl:ENSMUSG00000021404|Vega:OTTMUSG00000000705 +20708 Serpinb6b MGI:MGI:894688|Ensembl:ENSMUSG00000042842|Vega:OTTMUSG00000000698 +20709 Serpinb9f MGI:MGI:894671|Ensembl:ENSMUSG00000038327|Vega:OTTMUSG00000016794 +20710 Serpinb9e MGI:MGI:894672|Ensembl:ENSMUSG00000062342|Vega:OTTMUSG00000000706 +20711 Spi15 MGI:MGI:894673 +20712 Spi16 MGI:MGI:894674 +20713 Serpini1 MGI:MGI:1194506|Ensembl:ENSMUSG00000027834|Vega:OTTMUSG00000021878 +20714 Serpina3k MGI:MGI:98377|Ensembl:ENSMUSG00000058207|Vega:OTTMUSG00000035427 +20715 Serpina3g MGI:MGI:105046 +20716 Serpina3n MGI:MGI:105045|Ensembl:ENSMUSG00000021091|Vega:OTTMUSG00000016315 +20717 Serpina3m MGI:MGI:98378|Ensembl:ENSMUSG00000079012|Vega:OTTMUSG00000035429 +20719 Serpinb6a MGI:MGI:103123|Ensembl:ENSMUSG00000060147|Vega:OTTMUSG00000000739 +20720 Serpine2 MGI:MGI:101780|Ensembl:ENSMUSG00000026249|Vega:OTTMUSG00000021751 +20723 Serpinb9 MGI:MGI:106603|Ensembl:ENSMUSG00000045827|Vega:OTTMUSG00000000696 +20724 Serpinb5 MGI:MGI:109579|Ensembl:ENSMUSG00000067006|Vega:OTTMUSG00000020990 +20725 Serpinb8 MGI:MGI:894657|Ensembl:ENSMUSG00000026315|Vega:OTTMUSG00000020994 +20726 Serpinb9d MGI:MGI:894667|Ensembl:ENSMUSG00000054266|Vega:OTTMUSG00000000703 +20728 Spic MGI:MGI:1341168|Ensembl:ENSMUSG00000004359|Vega:OTTMUSG00000031753 +20729 Spin1 MGI:MGI:109242|Ensembl:ENSMUSG00000021395 +20730 Spink1 MGI:MGI:106202|Ensembl:ENSMUSG00000024503 +20731 Spink4 MGI:MGI:1341848|Ensembl:ENSMUSG00000028415|Vega:OTTMUSG00000006608 +20732 Spint1 MGI:MGI:1338033|Ensembl:ENSMUSG00000027315|Vega:OTTMUSG00000015880 +20733 Spint2 MGI:MGI:1338031|Ensembl:ENSMUSG00000074227|Vega:OTTMUSG00000059216 +20737 Spn MGI:MGI:98384|Ensembl:ENSMUSG00000051457|Vega:OTTMUSG00000029411 +20738 Spn-ps MGI:MGI:104964 +20739 Spta1 MGI:MGI:98385|Ensembl:ENSMUSG00000026532|Vega:OTTMUSG00000029638 +20740 Sptan1 MGI:MGI:98386|Ensembl:ENSMUSG00000057738|Vega:OTTMUSG00000016728 +20741 Sptb MGI:MGI:98387|Ensembl:ENSMUSG00000021061|Vega:OTTMUSG00000035470 +20742 Sptbn1 MGI:MGI:98388|Ensembl:ENSMUSG00000020315|Vega:OTTMUSG00000005341 +20743 Sptbn2 MGI:MGI:1313261|Ensembl:ENSMUSG00000067889 +20744 Strbp MGI:MGI:104626|Ensembl:ENSMUSG00000026915|Vega:OTTMUSG00000012664 +20745 Spock1 MGI:MGI:105371|Ensembl:ENSMUSG00000056222|Vega:OTTMUSG00000049775 +20747 Spop MGI:MGI:1343085|Ensembl:ENSMUSG00000057522|Vega:OTTMUSG00000001659 +20750 Spp1 MGI:MGI:98389|Ensembl:ENSMUSG00000029304|Vega:OTTMUSG00000024389 +20751 Spr MGI:MGI:103078|Ensembl:ENSMUSG00000033735|Vega:OTTMUSG00000037795 +20753 Sprr1a MGI:MGI:106660|Ensembl:ENSMUSG00000050359|Vega:OTTMUSG00000042112 +20754 Sprr1b MGI:MGI:106659|Ensembl:ENSMUSG00000048455|Vega:OTTMUSG00000051839 +20755 Sprr2a1 MGI:MGI:1330350|Ensembl:ENSMUSG00000078664|Vega:OTTMUSG00000051825 +20756 Sprr2b MGI:MGI:1330352|Ensembl:ENSMUSG00000050092|Vega:OTTMUSG00000051831 +20757 Sprr2c-ps MGI:MGI:1330351 +20758 Sprr2d MGI:MGI:1330347|Ensembl:ENSMUSG00000042212|Vega:OTTMUSG00000030583 +20759 Sprr2e MGI:MGI:1330346|Ensembl:ENSMUSG00000055030|Vega:OTTMUSG00000051834 +20760 Sprr2f MGI:MGI:1330349|Ensembl:ENSMUSG00000050635|Vega:OTTMUSG00000051835 +20761 Sprr2g MGI:MGI:1330348|Ensembl:ENSMUSG00000046203|Vega:OTTMUSG00000049786 +20762 Sprr2h MGI:MGI:1330343|Ensembl:ENSMUSG00000046259|Vega:OTTMUSG00000051836 +20763 Sprr2i MGI:MGI:1330309|Ensembl:ENSMUSG00000042157|Vega:OTTMUSG00000036506 +20764 Sprr2j-ps MGI:MGI:1330345|Ensembl:ENSMUSG00000027925|Vega:OTTMUSG00000051837 +20765 Sprr2k MGI:MGI:1330344|Ensembl:ENSMUSG00000054215|Vega:OTTMUSG00000036742 +20766 Sprr3 MGI:MGI:1330237|Ensembl:ENSMUSG00000045539|Vega:OTTMUSG00000049808 +20767 sps MGI:MGI:98390 +20768 Sephs2 MGI:MGI:108388|Ensembl:ENSMUSG00000049091|Vega:OTTMUSG00000058499 +20770 Mucl2 MGI:MGI:98392|Ensembl:ENSMUSG00000036925|Vega:OTTMUSG00000056904 +20771 Mucl1 MGI:MGI:98393 +20773 Sptlc2 MGI:MGI:108074|Ensembl:ENSMUSG00000021036|Vega:OTTMUSG00000035626 +20775 Sqle MGI:MGI:109296|Ensembl:ENSMUSG00000022351|Vega:OTTMUSG00000034890 +20776 Tmie MGI:MGI:2159400|Ensembl:ENSMUSG00000049555|Vega:OTTMUSG00000021713 +20778 Scarb1 MGI:MGI:893578|Ensembl:ENSMUSG00000037936|Vega:OTTMUSG00000022742 +20779 Src MGI:MGI:98397|Ensembl:ENSMUSG00000027646|Vega:OTTMUSG00000016179 +20782 Srcs2 MGI:MGI:104601 +20784 Srcs4 MGI:MGI:104599 +20787 Srebf1 MGI:MGI:107606|Ensembl:ENSMUSG00000020538|Vega:OTTMUSG00000005809 +20788 Srebf2 MGI:MGI:107585|Ensembl:ENSMUSG00000022463 +20807 Srf MGI:MGI:106658|Ensembl:ENSMUSG00000015605 +20810 Srm MGI:MGI:102690|Ensembl:ENSMUSG00000006442|Vega:OTTMUSG00000010928 +20811 Srms MGI:MGI:101865|Ensembl:ENSMUSG00000027579|Vega:OTTMUSG00000016560 +20812 srn MGI:MGI:98421 +20813 Srp14 MGI:MGI:107169|Ensembl:ENSMUSG00000009549|Vega:OTTMUSG00000015233 +20815 Srpk1 MGI:MGI:106908|Ensembl:ENSMUSG00000004865|Vega:OTTMUSG00000024247 +20817 Srpk2 MGI:MGI:1201408|Ensembl:ENSMUSG00000062604|Vega:OTTMUSG00000053492 +20818 Srprb MGI:MGI:102964|Ensembl:ENSMUSG00000032553|Vega:OTTMUSG00000035366 +20819 Srst MGI:MGI:107677 +20821 Trim21 MGI:MGI:106657|Ensembl:ENSMUSG00000030966|Vega:OTTMUSG00000060441 +20822 Trove2 MGI:MGI:106652|Ensembl:ENSMUSG00000018199|Vega:OTTMUSG00000021864 +20823 Ssb MGI:MGI:98423|Ensembl:ENSMUSG00000068882|Vega:OTTMUSG00000013038 +20826 Snu13 MGI:MGI:893586|Ensembl:ENSMUSG00000063480|Vega:OTTMUSG00000035736 +20829 Ssm1 MGI:MGI:98425 +20832 Ssr4 MGI:MGI:1099464|Ensembl:ENSMUSG00000002014|Vega:OTTMUSG00000018078 +20833 Ssrp1 MGI:MGI:107912|Ensembl:ENSMUSG00000027067|Vega:OTTMUSG00000013453 +20834 Znrf4 MGI:MGI:1341258|Ensembl:ENSMUSG00000044526 +20837 st MGI:MGI:98426 +20840 Stac MGI:MGI:1201400|Ensembl:ENSMUSG00000032502|Vega:OTTMUSG00000026418 +20841 Zfp143 MGI:MGI:1277969|Ensembl:ENSMUSG00000061079|Vega:OTTMUSG00000060169 +20842 Stag1 MGI:MGI:1098658|Ensembl:ENSMUSG00000037286|Vega:OTTMUSG00000034031 +20843 Stag2 MGI:MGI:1098583|Ensembl:ENSMUSG00000025862|Vega:OTTMUSG00000017467 +20844 Stam MGI:MGI:1329014|Ensembl:ENSMUSG00000026718|Vega:OTTMUSG00000011399 +20845 Star MGI:MGI:102760|Ensembl:ENSMUSG00000031574|Vega:OTTMUSG00000031856 +20846 Stat1 MGI:MGI:103063|Ensembl:ENSMUSG00000026104|Vega:OTTMUSG00000046734 +20847 Stat2 MGI:MGI:103039|Ensembl:ENSMUSG00000040033 +20848 Stat3 MGI:MGI:103038|Ensembl:ENSMUSG00000004040|Vega:OTTMUSG00000002128 +20849 Stat4 MGI:MGI:103062|Ensembl:ENSMUSG00000062939|Vega:OTTMUSG00000046732 +20850 Stat5a MGI:MGI:103036|Ensembl:ENSMUSG00000004043|Vega:OTTMUSG00000002125 +20851 Stat5b MGI:MGI:103035|Ensembl:ENSMUSG00000020919|Vega:OTTMUSG00000002127 +20852 Stat6 MGI:MGI:103034|Ensembl:ENSMUSG00000002147|Vega:OTTMUSG00000031818 +20853 Stau1 MGI:MGI:1338864|Ensembl:ENSMUSG00000039536|Vega:OTTMUSG00000001134 +20854 stb MGI:MGI:98429 +20855 Stc1 MGI:MGI:109131|Ensembl:ENSMUSG00000014813 +20856 Stc2 MGI:MGI:1316731|Ensembl:ENSMUSG00000020303|Vega:OTTMUSG00000005360 +20859 Sult2a1 MGI:MGI:98430|Ensembl:ENSMUSG00000078798|Vega:OTTMUSG00000048118 +20860 Sult1e1 MGI:MGI:98431|Ensembl:ENSMUSG00000029272|Vega:OTTMUSG00000054067 +20861 Stfa1 MGI:MGI:106198|Ensembl:ENSMUSG00000071562 +20862 Stfa2 MGI:MGI:106197|Ensembl:ENSMUSG00000022902 +20863 Stfa3 MGI:MGI:106196|Ensembl:ENSMUSG00000054905 +20866 Stim1 MGI:MGI:107476|Ensembl:ENSMUSG00000030987|Vega:OTTMUSG00000060544 +20867 Stip1 MGI:MGI:109130|Ensembl:ENSMUSG00000024966 +20868 Stk10 MGI:MGI:1099439|Ensembl:ENSMUSG00000020272|Vega:OTTMUSG00000005381 +20869 Stk11 MGI:MGI:1341870|Ensembl:ENSMUSG00000003068|Vega:OTTMUSG00000000002 +20870 Dyrk1c MGI:MGI:1203485 +20871 Aurkc MGI:MGI:1321119|Ensembl:ENSMUSG00000070837|Vega:OTTMUSG00000060137 +20872 Stk16 MGI:MGI:1313271|Ensembl:ENSMUSG00000026201|Vega:OTTMUSG00000029626 +20873 Plk4 MGI:MGI:101783|Ensembl:ENSMUSG00000025758|Vega:OTTMUSG00000035882 +20874 Slk MGI:MGI:103241|Ensembl:ENSMUSG00000025060|Vega:OTTMUSG00000029687 +20877 Aurkb MGI:MGI:107168|Ensembl:ENSMUSG00000020897|Vega:OTTMUSG00000005961 +20878 Aurka MGI:MGI:894678|Ensembl:ENSMUSG00000027496|Vega:OTTMUSG00000016161 +20882 stm MGI:MGI:98434 +20887 Sult1a1 MGI:MGI:102896|Ensembl:ENSMUSG00000030711|Vega:OTTMUSG00000025254 +20888 Sult1c1 MGI:MGI:102928|Ensembl:ENSMUSG00000023943|Vega:OTTMUSG00000028468 +20890 Wnt8a MGI:MGI:107924|Ensembl:ENSMUSG00000012282 +20892 Cenpx MGI:MGI:894324|Ensembl:ENSMUSG00000025144|Vega:OTTMUSG00000004086 +20893 Bhlhe40 MGI:MGI:1097714|Ensembl:ENSMUSG00000030103|Vega:OTTMUSG00000035997 +20897 Stra6 MGI:MGI:107742|Ensembl:ENSMUSG00000032327|Vega:OTTMUSG00000024607 +20899 Stra8 MGI:MGI:107917|Ensembl:ENSMUSG00000029848|Vega:OTTMUSG00000022789 +20901 Strap MGI:MGI:1329037|Ensembl:ENSMUSG00000030224|Vega:OTTMUSG00000023526 +20905 Sts MGI:MGI:98438 +20906 stu MGI:MGI:98439 +20907 Stx1a MGI:MGI:109355|Ensembl:ENSMUSG00000007207|Vega:OTTMUSG00000016270 +20908 Stx3 MGI:MGI:103077|Ensembl:ENSMUSG00000041488|Vega:OTTMUSG00000061360 +20909 Stx4a MGI:MGI:893577|Ensembl:ENSMUSG00000030805|Vega:OTTMUSG00000030969 +20910 Stxbp1 MGI:MGI:107363|Ensembl:ENSMUSG00000026797|Vega:OTTMUSG00000012527 +20911 Stxbp2 MGI:MGI:107370|Ensembl:ENSMUSG00000004626|Vega:OTTMUSG00000027109 +20912 Stxbp3 MGI:MGI:107362|Ensembl:ENSMUSG00000027882|Vega:OTTMUSG00000007265 +20913 Stxbp4 MGI:MGI:1342296|Ensembl:ENSMUSG00000020546|Vega:OTTMUSG00000001602 +20914 sty MGI:MGI:98440 +20915 su MGI:MGI:98441 +20916 Sucla2 MGI:MGI:1306775|Ensembl:ENSMUSG00000022110|Vega:OTTMUSG00000035022 +20917 Suclg2 MGI:MGI:1306824|Ensembl:ENSMUSG00000061838|Vega:OTTMUSG00000057813 +20918 Eif1 MGI:MGI:105125|Ensembl:ENSMUSG00000035530|Vega:OTTMUSG00000006270 +20922 Supt4a MGI:MGI:107416|Ensembl:ENSMUSG00000020485|Vega:OTTMUSG00000001315 +20924 Supt5 MGI:MGI:1202400|Ensembl:ENSMUSG00000003435|Vega:OTTMUSG00000059053 +20926 Supt6 MGI:MGI:107726|Ensembl:ENSMUSG00000002052|Vega:OTTMUSG00000000107 +20927 Abcc8 MGI:MGI:1352629|Ensembl:ENSMUSG00000040136|Vega:OTTMUSG00000058299 +20928 Abcc9 MGI:MGI:1352630|Ensembl:ENSMUSG00000030249|Vega:OTTMUSG00000057137 +20930 Surf1 MGI:MGI:98443|Ensembl:ENSMUSG00000015790|Vega:OTTMUSG00000011739 +20931 Surf2 MGI:MGI:98444|Ensembl:ENSMUSG00000014873|Vega:OTTMUSG00000011737 +20932 Surf4 MGI:MGI:98445|Ensembl:ENSMUSG00000014867|Vega:OTTMUSG00000011741 +20933 Med22 MGI:MGI:98446|Ensembl:ENSMUSG00000015776|Vega:OTTMUSG00000011738 +20935 Surf6 MGI:MGI:98447|Ensembl:ENSMUSG00000036160|Vega:OTTMUSG00000011581 +20937 Suv39h1 MGI:MGI:1099440|Ensembl:ENSMUSG00000039231|Vega:OTTMUSG00000017258 +20939 Sva MGI:MGI:102785|Ensembl:ENSMUSG00000023289|Vega:OTTMUSG00000026931 +20941 Svs4 MGI:MGI:98450|Ensembl:ENSMUSG00000016998|Vega:OTTMUSG00000001083 +20944 Svs5 MGI:MGI:98453|Ensembl:ENSMUSG00000017004|Vega:OTTMUSG00000001085 +20945 Svs6 MGI:MGI:106178|Ensembl:ENSMUSG00000017000|Vega:OTTMUSG00000001086 +20947 Swap70 MGI:MGI:1298390|Ensembl:ENSMUSG00000031015|Vega:OTTMUSG00000060174 +20954 sy MGI:MGI:98457 +20955 Vamp7 MGI:MGI:1096399|Ensembl:ENSMUSG00000051412 +20957 Sycp1 MGI:MGI:105931|Ensembl:ENSMUSG00000027855|Vega:OTTMUSG00000054718 +20958 Sycp1-ps1 MGI:MGI:1098279|Ensembl:ENSMUSG00000109116 +20962 Sycp3 MGI:MGI:109542|Ensembl:ENSMUSG00000020059|Vega:OTTMUSG00000023468 +20963 Syk MGI:MGI:99515|Ensembl:ENSMUSG00000021457|Vega:OTTMUSG00000031741 +20964 Syn1 MGI:MGI:98460|Ensembl:ENSMUSG00000037217|Vega:OTTMUSG00000017181 +20965 Syn2 MGI:MGI:103020|Ensembl:ENSMUSG00000009394|Vega:OTTMUSG00000056610 +20969 Sdc1 MGI:MGI:1349162|Ensembl:ENSMUSG00000020592|Vega:OTTMUSG00000033390 +20970 Sdc3 MGI:MGI:1349163|Ensembl:ENSMUSG00000025743|Vega:OTTMUSG00000009594 +20971 Sdc4 MGI:MGI:1349164|Ensembl:ENSMUSG00000017009|Vega:OTTMUSG00000001157 +20972 Syngr1 MGI:MGI:1328323|Ensembl:ENSMUSG00000022415|Vega:OTTMUSG00000016389 +20973 Syngr2 MGI:MGI:1328324|Ensembl:ENSMUSG00000048277|Vega:OTTMUSG00000003678 +20974 Syngr3 MGI:MGI:1341881|Ensembl:ENSMUSG00000007021|Vega:OTTMUSG00000028128 +20975 Synj2 MGI:MGI:1201671|Ensembl:ENSMUSG00000023805|Vega:OTTMUSG00000020122 +20977 Syp MGI:MGI:98467|Ensembl:ENSMUSG00000031144|Vega:OTTMUSG00000017756 +20979 Syt1 MGI:MGI:99667|Ensembl:ENSMUSG00000035864|Vega:OTTMUSG00000016266 +20980 Syt2 MGI:MGI:99666|Ensembl:ENSMUSG00000026452|Vega:OTTMUSG00000029462 +20981 Syt3 MGI:MGI:99665|Ensembl:ENSMUSG00000030731|Vega:OTTMUSG00000031834 +20983 Syt4 MGI:MGI:101759|Ensembl:ENSMUSG00000024261 +20997 T MGI:MGI:98472|Ensembl:ENSMUSG00000062327|Vega:OTTMUSG00000026263 +20998 t MGI:MGI:105076 +20999 T(;16)129Dn MGI:MGI:104214 +21000 T(1;10)11Ad MGI:MGI:103648 +21001 T(1;10)11Ad MGI:MGI:103649 +21002 T(1;12)52H MGI:MGI:103650 +21003 T(1;12)52H MGI:MGI:103651 +21004 T(1;13)1Wa MGI:MGI:103652 +21005 T(1;13)1Wa MGI:MGI:103653 +21006 T(1;13)70H MGI:MGI:103654 +21007 T(1;13)70H MGI:MGI:103655 +21008 T(1;14)1Po MGI:MGI:103656 +21009 T(1;14)1Po MGI:MGI:103657 +21010 T(1;14)5Gso MGI:MGI:103658 +21011 T(1;14)5Gso MGI:MGI:103659 +21012 T(1C2;16C3)45Dn MGI:MGI:103660 +21013 T(1C2;16C3)45Dn MGI:MGI:103661 +21014 T(1;17)190Ca MGI:MGI:103662 +21015 T(1;17)190Ca MGI:MGI:103663 +21016 T(1;2)5Ca MGI:MGI:103631 +21017 T(1;2)5Ca MGI:MGI:103632 +21018 T(1;6)42Ad MGI:MGI:103636 +21019 T(1;6)42Ad MGI:MGI:103637 +21020 T(1;7)27Ad MGI:MGI:103638 +21021 T(1;7)27Ad MGI:MGI:103639 +21022 T(1;7)40H MGI:MGI:103640 +21023 T(1;7)40H MGI:MGI:103641 +21024 T(1;7)49H MGI:MGI:103642 +21025 T(1;7)49H MGI:MGI:103643 +21026 T(1;8)63H MGI:MGI:103644 +21027 T(1;8)63H MGI:MGI:103645 +21028 T(1;9)27H MGI:MGI:103646 +21029 T(1;9)27H MGI:MGI:103647 +21030 T(10;11)75H MGI:MGI:1197029 +21031 T(10;11)75H MGI:MGI:1197014 +21032 T(10;11)Rl MGI:MGI:104072 +21033 T(10;11)Rl MGI:MGI:104073 +21034 T(10;12)10Rl MGI:MGI:104074 +21035 T(10;12)10Rl MGI:MGI:104075 +21036 T(10;12)38Ad MGI:MGI:104076 +21037 T(10;12)38Ad MGI:MGI:104077 +21038 T(10;13)199H MGI:MGI:104081 +21039 T(10;13)199H MGI:MGI:104080 +21040 T(10;13)3Ad MGI:MGI:104078 +21041 T(10;13)3Ad MGI:MGI:104079 +21042 T(10;14)8Rk MGI:MGI:104082 +21043 T(10;14)8Rk MGI:MGI:104083 +21044 T(10;16)232Dn MGI:MGI:104086 +21045 T(10;16)232Dn MGI:MGI:104087 +21046 T(10;16)59H MGI:MGI:104084 +21047 T(10;16)59H MGI:MGI:104085 +21048 T(10;17)11Rl MGI:MGI:104088 +21049 T(10;17)11Rl MGI:MGI:104089 +21050 T(10;18)12Rl MGI:MGI:104090 +21051 T(10;18)12Rl MGI:MGI:104091 +21052 T(10;18)18H MGI:MGI:104093 +21053 T(10;18)18H MGI:MGI:104092 +21054 T(10;18)21Ad MGI:MGI:104094 +21055 T(10;18)21Ad MGI:MGI:104095 +21056 T(11;13)41Ad MGI:MGI:104108 +21057 T(11;13)41Ad MGI:MGI:104109 +21058 T(11;13)56H MGI:MGI:104110 +21059 T(11;13)56H MGI:MGI:104111 +21060 T(11B1;16B5)233Dn MGI:MGI:104116 +21061 T(11B1;16B5)233Dn MGI:MGI:104117 +21062 T(11A2;16B3)238Dn MGI:MGI:104118 +21063 T(11A2;16B3)238Dn MGI:MGI:104119 +21064 T(11;16)29Ad MGI:MGI:104112 +21065 T(11;16)29Ad MGI:MGI:104113 +21066 T(11;16A)53Dn MGI:MGI:104114 +21067 T(11;16A)53Dn MGI:MGI:104115 +21068 T(11;17)202Dn MGI:MGI:104120 +21069 T(11;17)202Dn MGI:MGI:104121 +21070 T(11;19)42H MGI:MGI:104123 +21071 T(11;19)42H MGI:MGI:104122 +21072 T(12;17)4Rk MGI:MGI:104133 +21073 T(12;17)4Rk MGI:MGI:104134 +21074 T(12;17)9Gso MGI:MGI:104135 +21075 T(12;17)9Gso MGI:MGI:104136 +21076 T(13;14)69H MGI:MGI:108153 +21077 T(13;14)69H MGI:MGI:108152 +21078 T(13;17)1Lub MGI:MGI:104147 +21079 T(13;17)1Lub MGI:MGI:104148 +21080 T(14;15)6Ca MGI:MGI:104172 +21081 T(14;15)6Ca MGI:MGI:104171 +21082 T(14E4or5;16B5)225Dn MGI:MGI:104173 +21083 T(14E4or5;16B5)225Dn MGI:MGI:104174 +21084 T(14;18)12Ad MGI:MGI:104175 +21085 T(14;18)12Ad MGI:MGI:104176 +21086 T(14;18)14Ad MGI:MGI:104177 +21087 T(14;18)14Ad MGI:MGI:104178 +21088 T(15;16)198Dn MGI:MGI:104189 +21089 T(15;16)198Dn MGI:MGI:104190 +21090 T(15;16)1Kl MGI:MGI:108469 +21091 T(15;16)1Kl MGI:MGI:109236 +21092 T(15E;16B1)60Dn MGI:MGI:104187 +21093 T(15E;16B1)60Dn MGI:MGI:104188 +21094 T(15;18)22Ad MGI:MGI:104191 +21095 T(15;18)22Ad MGI:MGI:104192 +21096 T(15;19)6Gso MGI:MGI:104193 +21097 T(15;19)6Gso MGI:MGI:104194 +21098 T(16;17)43H MGI:MGI:104215 +21099 T(16;17)43H MGI:MGI:104216 +21100 T(16C3-4;17A2)65Dn MGI:MGI:104220 +21101 T(16C3-4;17A2)65Dn MGI:MGI:104219 +21102 T(16;17)7Gso MGI:MGI:104217 +21103 T(16;17)7Gso MGI:MGI:104218 +21104 T(16;19)239Dn MGI:MGI:104221 +21105 T(16;19)239Dn MGI:MGI:104222 +21106 T(17;18)4Gso MGI:MGI:104232 +21107 T(17;18)4Gso MGI:MGI:104233 +21108 T(2;10)14Ad MGI:MGI:103716 +21109 T(2;10)14Ad MGI:MGI:103717 +21110 T(2;11)30H MGI:MGI:103720 +21111 T(2;11)30H MGI:MGI:103721 +21112 T(2D;11B5)4Dn MGI:MGI:103718 +21113 T(2D;11B5)4Dn MGI:MGI:103719 +21114 T(2;12)47Dn MGI:MGI:103722 +21115 T(2;12)47Dn MGI:MGI:103723 +21116 T(2;14)1Gso MGI:MGI:103724 +21117 T(2;14)1Gso MGI:MGI:103725 +21118 T(2;14)48H MGI:MGI:103726 +21119 T(2;14)48H MGI:MGI:103727 +21120 T(2;15)15Ad MGI:MGI:103728 +21121 T(2;15)15Ad MGI:MGI:103729 +21122 T(2;15)45Ad MGI:MGI:108154 +21123 T(2;15)45Ad MGI:MGI:108155 +21124 T(2;16)28H MGI:MGI:103730 +21125 T(2;16)28H MGI:MGI:103731 +21126 T(2;19)68H MGI:MGI:103732 +21127 T(2;19)68H MGI:MGI:103733 +21128 T(2;3)24H MGI:MGI:103689 +21129 T(2;3)24H MGI:MGI:103688 +21130 T(2;4)13H MGI:MGI:103697 +21131 T(2;4)13H MGI:MGI:103696 +21132 T(2;4)1Ca MGI:MGI:103691 +21133 T(2;4)1Ca MGI:MGI:103690 +21134 T(2;4)1Go MGI:MGI:103693 +21135 T(2;4)1Go MGI:MGI:103692 +21136 T(2;4)1Sn MGI:MGI:103695 +21137 T(2;4)1Sn MGI:MGI:103694 +21138 T(2;4)32Ad MGI:MGI:103698 +21139 T(2;4)32Ad MGI:MGI:103699 +21140 T(2C1-2;4D)41Dn MGI:MGI:103700 +21141 T(2C1-2;4D)41Dn MGI:MGI:103701 +21142 T(2;5)43Ad MGI:MGI:108156 +21143 T(2;5)43Ad MGI:MGI:108157 +21144 T(2;6)7Ca MGI:MGI:103703 +21145 T(2;6)7Ca MGI:MGI:103702 +21146 T(2;6)97Dn MGI:MGI:103704 +21147 T(2;6)97Dn MGI:MGI:103705 +21148 T(2;8)26H MGI:MGI:103709 +21149 T(2;8)26H MGI:MGI:103708 +21150 T(2;8)2Wa MGI:MGI:103707 +21151 T(2;8)2Wa MGI:MGI:103706 +21152 T(2;8)36Ad MGI:MGI:103710 +21153 T(2;8)36Ad MGI:MGI:103711 +21154 T(2;9)11H MGI:MGI:103713 +21155 T(2;9)11H MGI:MGI:103712 +21156 T(2;9)13Ad MGI:MGI:103714 +21157 T(2;9)13Ad MGI:MGI:103715 +21158 T(3;10)61H MGI:MGI:103763 +21159 T(3;10)61H MGI:MGI:103764 +21160 T(3;11)16Ad MGI:MGI:103765 +21161 T(3;11)16Ad MGI:MGI:103766 +21162 T(3;12)30Rk MGI:MGI:103767 +21163 T(3;12)30Rk MGI:MGI:103768 +21164 T(3;12)58H MGI:MGI:103769 +21165 T(3;12)58H MGI:MGI:103770 +21166 T(3;14)28Ad MGI:MGI:103771 +21167 T(3;14)28Ad MGI:MGI:103772 +21168 T(3;19)25Ad MGI:MGI:103773 +21169 T(3;19)25Ad MGI:MGI:103774 +21170 T(3;4)5Rk MGI:MGI:103759 +21171 T(3;4)5Rk MGI:MGI:103760 +21172 T(3;6)37Ad MGI:MGI:103761 +21173 T(3;6)37Ad MGI:MGI:103762 +21174 T(4;12)47H MGI:MGI:103820 +21175 T(4;12)47H MGI:MGI:103821 +21176 T(4;16)31Ad MGI:MGI:103822 +21177 T(4;16)31Ad MGI:MGI:103823 +21178 T(4;17)2Lws MGI:MGI:103824 +21179 T(4;17)2Lws MGI:MGI:103825 +21180 T(4;19)1Ad MGI:MGI:103826 +21181 T(4;19)1Ad MGI:MGI:103827 +21182 T(4;5)46H MGI:MGI:103809 +21183 T(4;5)46H MGI:MGI:103810 +21184 T(4;6)48Ad MGI:MGI:108162 +21185 T(4;6)48Ad MGI:MGI:108163 +21186 T(4;7)1Rl MGI:MGI:103811 +21187 T(4;7)1Rl MGI:MGI:103812 +21188 T(4;8)Tp(8q8p)36H MGI:MGI:103813 +21189 T(4;8)Tp(8q8p)36H MGI:MGI:103814 +21190 T(4;8)Tp(8q8p)36H MGI:MGI:103815 +21191 T(4;9)45H MGI:MGI:103818 +21192 T(4;9)45H MGI:MGI:103819 +21193 T(4;In8)36H MGI:MGI:103816 +21194 T(4;In8)36H MGI:MGI:103817 +21195 T(5;10)9Rl MGI:MGI:103864 +21196 T(5;10)9Rl MGI:MGI:103865 +21197 T(5;11)17Ad MGI:MGI:103866 +21198 T(5;11)17Ad MGI:MGI:103867 +21199 T(5;11)542Ct MGI:MGI:108171 +21200 T(5;11)542Ct MGI:MGI:108172 +21201 T(5;11)57H MGI:MGI:103868 +21202 T(5;11)57H MGI:MGI:103869 +21203 T(5;12)31H MGI:MGI:103870 +21204 T(5;12)31H MGI:MGI:103871 +21205 T(5;13)264Ca MGI:MGI:103874 +21206 T(5;13)264Ca MGI:MGI:103875 +21207 T(5;13)5Ad MGI:MGI:103872 +21208 T(5;13)5Ad MGI:MGI:103873 +21209 T(5;14)2Gso MGI:MGI:103876 +21210 T(5;14)2Gso MGI:MGI:103877 +21211 T(5;15)49Ad MGI:MGI:108160 +21212 T(5;15)49Ad MGI:MGI:108161 +21213 T(5;15)4Ad MGI:MGI:103878 +21214 T(5;15)4Ad MGI:MGI:103879 +21215 T(5;15)8Gso MGI:MGI:103880 +21216 T(5;15)8Gso MGI:MGI:103881 +21217 T(5;16)53H MGI:MGI:103882 +21218 T(5;16)53H MGI:MGI:103883 +21219 T(5;16)55H MGI:MGI:103884 +21220 T(5;16)55H MGI:MGI:103885 +21221 T(5;7)30Ad MGI:MGI:103860 +21222 T(5;7)30Ad MGI:MGI:103861 +21223 T(5;7)50Ad MGI:MGI:108158 +21224 T(5;7)50Ad MGI:MGI:108159 +21225 T(5;8)3Rk MGI:MGI:103862 +21226 T(5;8)3Rk MGI:MGI:103863 +21227 T(6;)39H MGI:MGI:103911 +21228 T(6;10)18Ad MGI:MGI:103918 +21229 T(6;10)18Ad MGI:MGI:103919 +21230 T(6;12)32H MGI:MGI:103920 +21231 T(6;12)32H MGI:MGI:103921 +21232 T(6;13)3Gso MGI:MGI:103922 +21233 T(6;13)3Gso MGI:MGI:103923 +21234 T(6;13)6Ad MGI:MGI:103924 +21235 T(6;13)6Ad MGI:MGI:103925 +21236 T(6F;18C)57Dn MGI:MGI:103928 +21237 T(6F;18C)57Dn MGI:MGI:103929 +21238 T(6;7)17Ad MGI:MGI:103912 +21239 T(6;7)17Ad MGI:MGI:103913 +21240 T(6;7)51H MGI:MGI:103914 +21241 T(6;7)51H MGI:MGI:103915 +21242 T(6;8)2Ad MGI:MGI:103917 +21243 T(6;8)2Ad MGI:MGI:103916 +21244 T(7;11)40Ad MGI:MGI:103953 +21245 T(7;11)40Ad MGI:MGI:103954 +21246 T(7;11)64H MGI:MGI:103955 +21247 T(7;11)64H MGI:MGI:103956 +21248 T(7;11)65H MGI:MGI:103957 +21249 T(7;11)65H MGI:MGI:103958 +21250 T(7;12)19Ad MGI:MGI:103959 +21251 T(7;12)19Ad MGI:MGI:103960 +21252 T(7;13)43Ad MGI:MGI:103963 +21253 T(7;13)43Ad MGI:MGI:103964 +21254 T(7;13)7Ad MGI:MGI:103961 +21255 T(7;13)7Ad MGI:MGI:103962 +21256 T(7;14)2Iem MGI:MGI:103965 +21257 T(7;14)2Iem MGI:MGI:103966 +21258 T(7;15)9H MGI:MGI:103967 +21259 T(7;15)9H MGI:MGI:103968 +21260 T(7;16)235Dn MGI:MGI:103971 +21261 T(7;16)235Dn MGI:MGI:103972 +21262 T(7;16)67H MGI:MGI:103969 +21263 T(7;16)67H MGI:MGI:103970 +21264 T(7;17)3Bkm MGI:MGI:103973 +21265 T(7;17)3Bkm MGI:MGI:103974 +21266 T(7;18)50H MGI:MGI:103975 +21267 T(7;18)50H MGI:MGI:103976 +21268 T(7;19)10Gso MGI:MGI:103977 +21269 T(7;19)10Gso MGI:MGI:103978 +21270 T(7;19)145H MGI:MGI:103979 +21271 T(7;19)145H MGI:MGI:103980 +21272 T(8;10)8Ad MGI:MGI:104006 +21273 T(8;10)8Ad MGI:MGI:104007 +21274 T(8A4;12D1)69Dn MGI:MGI:104008 +21275 T(8A4;12D1)69Dn MGI:MGI:104009 +21276 T(8C3;16B5)164Dn MGI:MGI:104012 +21277 T(8C3;16B5)164Dn MGI:MGI:104013 +21278 T(8;16)17H MGI:MGI:104010 +21279 T(8;16)17H MGI:MGI:104011 +21280 T(9;10)62H MGI:MGI:104034 +21281 T(9;10)62H MGI:MGI:104035 +21282 T(9;11)9Ad MGI:MGI:104036 +21283 T(9;11)9Ad MGI:MGI:104037 +21284 T(9;12)20Ad MGI:MGI:104038 +21285 T(9;12)20Ad MGI:MGI:104039 +21286 T(9;17)10Ad MGI:MGI:104040 +21287 T(9;17)10Ad MGI:MGI:104041 +21288 T(9;17)138Ca MGI:MGI:104042 +21289 T(9;17)138Ca MGI:MGI:104043 +21290 T(In1;5)44H MGI:MGI:103634 +21291 T(In1;5)44H MGI:MGI:103633 +21292 T(In1;5)44H MGI:MGI:103635 +21293 T(X;11)38H MGI:MGI:104274 +21294 T(X;11)38H MGI:MGI:104275 +21295 T(X;12)13Rl MGI:MGI:104276 +21296 T(X;12)13Rl MGI:MGI:104277 +21297 T(X;16)16H MGI:MGI:104278 +21298 T(X;16)16H MGI:MGI:104279 +21299 T(X;17)15Rl MGI:MGI:104280 +21300 T(X;17)15Rl MGI:MGI:104281 +21301 T(X;2)14Rl MGI:MGI:104246 +21302 T(X;2)14Rl MGI:MGI:104247 +21303 T(X;4)1Rl MGI:MGI:104249 +21304 T(X;4)1Rl MGI:MGI:104248 +21305 T(X;4)37H MGI:MGI:104255 +21306 T(X;4)37H MGI:MGI:104254 +21307 T(X;4)7Rl MGI:MGI:104251 +21308 T(X;4)7Rl MGI:MGI:104250 +21309 T(X;4)8Rl MGI:MGI:104253 +21310 T(X;4)8Rl MGI:MGI:104252 +21311 T(X;7)18Rl MGI:MGI:104271 +21312 T(X;7)18Rl MGI:MGI:104270 +21315 T(X;7)1Neu MGI:MGI:104257 +21316 T(X;7)1Neu MGI:MGI:104256 +21317 T(X;7)2Neu MGI:MGI:104259 +21318 T(X;7)2Neu MGI:MGI:104258 +21319 T(X;7)2Rl MGI:MGI:104263 +21320 T(X;7)2Rl MGI:MGI:104262 +21321 T(X;7)3Neu MGI:MGI:104261 +21322 T(X;7)3Neu MGI:MGI:104260 +21323 T(X;7)3Rl MGI:MGI:104265 +21324 T(X;7)3Rl MGI:MGI:104264 +21325 T(X;7)5Rl MGI:MGI:104267 +21326 T(X;7)5Rl MGI:MGI:104266 +21327 T(X;7)6Rl MGI:MGI:104269 +21328 T(X;7)6Rl MGI:MGI:104268 +21331 T2 MGI:MGI:104658 +21333 Tac1 MGI:MGI:98474|Ensembl:ENSMUSG00000061762|Vega:OTTMUSG00000042604 +21334 Tac2 MGI:MGI:98476|Ensembl:ENSMUSG00000025400 +21335 Tacc3 MGI:MGI:1341163|Ensembl:ENSMUSG00000037313|Vega:OTTMUSG00000025055 +21336 Tacr1 MGI:MGI:98475|Ensembl:ENSMUSG00000030043|Vega:OTTMUSG00000057802 +21337 Tacr2 MGI:MGI:98477|Ensembl:ENSMUSG00000020081 +21338 Tacr3 MGI:MGI:892968|Ensembl:ENSMUSG00000028172|Vega:OTTMUSG00000049886 +21339 Taf1a MGI:MGI:109578|Ensembl:ENSMUSG00000072258|Vega:OTTMUSG00000050605 +21340 Taf1b MGI:MGI:109577|Ensembl:ENSMUSG00000059669 +21341 Taf1c MGI:MGI:109576|Ensembl:ENSMUSG00000031832|Vega:OTTMUSG00000031111 +21343 Taf6 MGI:MGI:109129|Ensembl:ENSMUSG00000036980|Vega:OTTMUSG00000022698 +21345 Tagln MGI:MGI:106012|Ensembl:ENSMUSG00000032085|Vega:OTTMUSG00000063599 +21346 Tagln2 MGI:MGI:1312985|Ensembl:ENSMUSG00000026547|Vega:OTTMUSG00000021616 +21349 Tal1 MGI:MGI:98480|Ensembl:ENSMUSG00000028717|Vega:OTTMUSG00000008586 +21350 Tal2 MGI:MGI:99540|Ensembl:ENSMUSG00000028417|Vega:OTTMUSG00000007003 +21351 Taldo1 MGI:MGI:1274789|Ensembl:ENSMUSG00000025503|Vega:OTTMUSG00000027257 +21353 Tank MGI:MGI:107676|Ensembl:ENSMUSG00000064289|Vega:OTTMUSG00000013011 +21354 Tap1 MGI:MGI:98483|Ensembl:ENSMUSG00000037321|Vega:OTTMUSG00000036473 +21355 Tap2 MGI:MGI:98484|Ensembl:ENSMUSG00000024339|Vega:OTTMUSG00000026436 +21356 Tapbp MGI:MGI:1201689|Ensembl:ENSMUSG00000024308|Vega:OTTMUSG00000037070 +21357 Tarbp2 MGI:MGI:103027|Ensembl:ENSMUSG00000023051|Vega:OTTMUSG00000033455 +21360 Targ1 MGI:MGI:1100841 +21362 Targ3 MGI:MGI:1100843 +21366 Slc6a6 MGI:MGI:98488|Ensembl:ENSMUSG00000030096|Vega:OTTMUSG00000058000 +21367 Cntn2 MGI:MGI:104518|Ensembl:ENSMUSG00000053024|Vega:OTTMUSG00000049393 +21369 tb MGI:MGI:98489 +21371 Tbca MGI:MGI:107549|Ensembl:ENSMUSG00000042043 +21372 Tbl1x MGI:MGI:1336172|Ensembl:ENSMUSG00000025246|Vega:OTTMUSG00000017892 +21374 Tbp MGI:MGI:101838|Ensembl:ENSMUSG00000014767|Vega:OTTMUSG00000030550 +21375 Tbr1 MGI:MGI:107404|Ensembl:ENSMUSG00000035033|Vega:OTTMUSG00000013075 +21376 Tbrg1 MGI:MGI:1100877|Ensembl:ENSMUSG00000011114|Vega:OTTMUSG00000029970 +21377 Tbrg2 MGI:MGI:1100866 +21378 Tbrg3 MGI:MGI:1100876 +21379 Tbrg4 MGI:MGI:1100868|Ensembl:ENSMUSG00000000384|Vega:OTTMUSG00000005119 +21380 Tbx1 MGI:MGI:98493|Ensembl:ENSMUSG00000009097 +21384 Tbx15 MGI:MGI:1277234|Ensembl:ENSMUSG00000027868|Vega:OTTMUSG00000006867 +21385 Tbx2 MGI:MGI:98494|Ensembl:ENSMUSG00000000093|Vega:OTTMUSG00000001028 +21386 Tbx3 MGI:MGI:98495|Ensembl:ENSMUSG00000018604|Vega:OTTMUSG00000029655 +21387 Tbx4 MGI:MGI:102556|Ensembl:ENSMUSG00000000094|Vega:OTTMUSG00000001043 +21388 Tbx5 MGI:MGI:102541|Ensembl:ENSMUSG00000018263|Vega:OTTMUSG00000056236 +21389 Tbx6 MGI:MGI:102539|Ensembl:ENSMUSG00000030699|Vega:OTTMUSG00000037609 +21390 Tbxa2r MGI:MGI:98496|Ensembl:ENSMUSG00000034881 +21391 Tbxas1 MGI:MGI:98497|Ensembl:ENSMUSG00000029925|Vega:OTTMUSG00000034254 +21393 Tcap MGI:MGI:1330233|Ensembl:ENSMUSG00000007877|Vega:OTTMUSG00000002713 +21399 Tcea1 MGI:MGI:1196624|Ensembl:ENSMUSG00000033813|Vega:OTTMUSG00000042348 +21400 Tcea2 MGI:MGI:107368|Ensembl:ENSMUSG00000059540|Vega:OTTMUSG00000016809 +21401 Tcea3 MGI:MGI:1196908|Ensembl:ENSMUSG00000001604|Vega:OTTMUSG00000009868 +21402 Skp1a MGI:MGI:103575|Ensembl:ENSMUSG00000036309|Vega:OTTMUSG00000005625 +21405 Hnf1a MGI:MGI:98504|Ensembl:ENSMUSG00000029556|Vega:OTTMUSG00000014612 +21406 Tcf12 MGI:MGI:101877|Ensembl:ENSMUSG00000032228|Vega:OTTMUSG00000044751 +21407 Tcf15 MGI:MGI:104664|Ensembl:ENSMUSG00000068079|Vega:OTTMUSG00000015848 +21408 Zfp354a MGI:MGI:103172|Ensembl:ENSMUSG00000020364|Vega:OTTMUSG00000005592 +21410 Hnf1b MGI:MGI:98505|Ensembl:ENSMUSG00000020679|Vega:OTTMUSG00000000988 +21411 Tcf20 MGI:MGI:108399|Ensembl:ENSMUSG00000041852 +21412 Tcf21 MGI:MGI:1202715|Ensembl:ENSMUSG00000045680 +21413 Tcf4 MGI:MGI:98506|Ensembl:ENSMUSG00000053477|Vega:OTTMUSG00000021071 +21414 Tcf7 MGI:MGI:98507|Ensembl:ENSMUSG00000000782|Vega:OTTMUSG00000005622 +21415 Tcf7l1 MGI:MGI:1202876|Ensembl:ENSMUSG00000055799|Vega:OTTMUSG00000021200 +21416 Tcf7l2 MGI:MGI:1202879|Ensembl:ENSMUSG00000024985|Vega:OTTMUSG00000020410 +21417 Zeb1 MGI:MGI:1344313|Ensembl:ENSMUSG00000024238|Vega:OTTMUSG00000030924 +21418 Tfap2a MGI:MGI:104671|Ensembl:ENSMUSG00000021359 +21419 Tfap2b MGI:MGI:104672|Ensembl:ENSMUSG00000025927|Vega:OTTMUSG00000048274 +21420 Tfap2c MGI:MGI:106032|Ensembl:ENSMUSG00000028640|Vega:OTTMUSG00000016248 +21422 Tfcp2 MGI:MGI:98509|Ensembl:ENSMUSG00000009733 +21423 Tcf3 MGI:MGI:98510|Ensembl:ENSMUSG00000020167|Vega:OTTMUSG00000019126 +21425 Tfeb MGI:MGI:103270|Ensembl:ENSMUSG00000023990|Vega:OTTMUSG00000018354 +21426 Tfec MGI:MGI:1333760|Ensembl:ENSMUSG00000029553|Vega:OTTMUSG00000055811 +21427 Vps72 MGI:MGI:1202305|Ensembl:ENSMUSG00000008958|Vega:OTTMUSG00000019665 +21428 Mlx MGI:MGI:108398|Ensembl:ENSMUSG00000017801|Vega:OTTMUSG00000002688 +21429 Ubtf MGI:MGI:98512|Ensembl:ENSMUSG00000020923|Vega:OTTMUSG00000002765 +21430 tch MGI:MGI:98513 +21431 tcl0 MGI:MGI:98514 +21432 Tcl1 MGI:MGI:1097166|Ensembl:ENSMUSG00000041359|Vega:OTTMUSG00000042098 +21433 tcl12 MGI:MGI:98515 +21434 tcl4 MGI:MGI:98516 +21435 tclLub1 MGI:MGI:98517 +21436 tclLub2 MGI:MGI:98518 +21437 tclLub9 MGI:MGI:98519 +21438 tclPa1 MGI:MGI:98520 +21439 tclTuw11 MGI:MGI:98521 +21440 tclTuw12 MGI:MGI:98522 +21441 tclTuw2 MGI:MGI:98523 +21442 tclTuw20 MGI:MGI:98524 +21443 tclTuw24 MGI:MGI:98525 +21444 tclTuw25 MGI:MGI:98526 +21445 tclTuw27 MGI:MGI:98527 +21446 tclTuw28 MGI:MGI:98528 +21447 tclw12 MGI:MGI:98529 +21448 tclw18 MGI:MGI:98530 +21450 tclw73 MGI:MGI:98532 +21452 Tcn2 MGI:MGI:98534|Ensembl:ENSMUSG00000020432|Vega:OTTMUSG00000005043 +21453 Tcof1 MGI:MGI:892003|Ensembl:ENSMUSG00000024613|Vega:OTTMUSG00000039736 +21454 Tcp1 MGI:MGI:98535|Ensembl:ENSMUSG00000068039|Vega:OTTMUSG00000028087 +21455 Tcp1-ps1 MGI:MGI:98536 +21458 Tcp10 MGI:MGI:98539 +21459 Tcp10-ps MGI:MGI:98540 +21461 Tcp10a MGI:MGI:98541|Ensembl:ENSMUSG00000071322|Vega:OTTMUSG00000028059 +21462 Tcp10b MGI:MGI:98542|Ensembl:ENSMUSG00000055602|Vega:OTTMUSG00000037013 +21463 Tcp11 MGI:MGI:98544|Ensembl:ENSMUSG00000062859|Vega:OTTMUSG00000024206 +21473 Tcra MGI:MGI:98553 +21475 Tcra-J MGI:MGI:98555 +21507 Trav5-4 MGI:MGI:1196221|IMGT/GENE-DB:TRAV5-4 +21524 Tcra-V2 MGI:MGI:98563 +21526 Tcra-V2.2 MGI:MGI:99745 +21527 Tcra-V2.3 MGI:MGI:99744 +21528 Tcra-V2.4 MGI:MGI:98564 +21529 Tcra-V2.5 MGI:MGI:98565 +21530 Tcra-V2.6 MGI:MGI:98566 +21577 Tcrb MGI:MGI:98578 +21580 Tcrb-J MGI:MGI:98581 +21616 Tcrd-V1 MGI:MGI:98615 +21632 Tcrg-V1 MGI:MGI:98631|IMGT/GENE-DB:TRGV1 +21636 Trgv2 MGI:MGI:98632|IMGT/GENE-DB:TRGV2 +21637 Tcrg-V3 MGI:MGI:98633|IMGT/GENE-DB:TRGV3 +21638 Tcrg-V4 MGI:MGI:98634|IMGT/GENE-DB:TRGV4 +21639 Tcrg-V5 MGI:MGI:98635|IMGT/GENE-DB:TRGV5 +21640 Tcrg-V6 MGI:MGI:98636|IMGT/GENE-DB:TRGV6 +21641 Tcrg-V7 MGI:MGI:98637|IMGT/GENE-DB:TRGV7 +21642 tct1 MGI:MGI:98638 +21643 tct2 MGI:MGI:98639 +21645 Tcte1 MGI:MGI:98640|Ensembl:ENSMUSG00000023949 +21646 Tcte2 MGI:MGI:98641|Ensembl:ENSMUSG00000038347|Vega:OTTMUSG00000029014 +21647 Tcte3 MGI:MGI:98642|Ensembl:ENSMUSG00000079707 +21648 Dynlt1b MGI:MGI:98643|Ensembl:ENSMUSG00000096255 +21652 Phf1 MGI:MGI:98647|Ensembl:ENSMUSG00000024193 +21661 tda1 MGI:MGI:98656 +21662 tda2 MGI:MGI:98657 +21663 tda3 MGI:MGI:107894 +21664 Phlda1 MGI:MGI:1096880|Ensembl:ENSMUSG00000020205|Vega:OTTMUSG00000035222 +21665 Tdg MGI:MGI:108247|Ensembl:ENSMUSG00000034674|Vega:OTTMUSG00000024276 +21667 Tdgf1 MGI:MGI:98658|Ensembl:ENSMUSG00000032494|Vega:OTTMUSG00000052499 +21669 Tdgf1-ps2 MGI:MGI:107366 +21672 Prdx2 MGI:MGI:109486|Ensembl:ENSMUSG00000005161|Vega:OTTMUSG00000016959 +21673 Dntt MGI:MGI:98659|Ensembl:ENSMUSG00000025014 +21674 Sry MGI:MGI:98660|Ensembl:ENSMUSG00000069036|Vega:OTTMUSG00000045384 +21675 te MGI:MGI:98661 +21676 Tead1 MGI:MGI:101876|Ensembl:ENSMUSG00000055320|Vega:OTTMUSG00000036056 +21677 Tead2 MGI:MGI:104904|Ensembl:ENSMUSG00000030796|Vega:OTTMUSG00000025380 +21678 Tead3 MGI:MGI:109241|Ensembl:ENSMUSG00000002249|Vega:OTTMUSG00000024245 +21679 Tead4 MGI:MGI:106907|Ensembl:ENSMUSG00000030353|Vega:OTTMUSG00000022461 +21681 Alyref MGI:MGI:1341044|Ensembl:ENSMUSG00000025134|Vega:OTTMUSG00000004088 +21682 Tec MGI:MGI:98662|Ensembl:ENSMUSG00000029217|Vega:OTTMUSG00000025011 +21683 Tecta MGI:MGI:109575|Ensembl:ENSMUSG00000037705|Vega:OTTMUSG00000034859 +21684 Tectb MGI:MGI:109574|Ensembl:ENSMUSG00000024979|Vega:OTTMUSG00000028257 +21685 Tef MGI:MGI:98663|Ensembl:ENSMUSG00000022389|Vega:OTTMUSG00000035246 +21687 Tek MGI:MGI:98664|Ensembl:ENSMUSG00000006386|Vega:OTTMUSG00000007859 +21689 Tekt1 MGI:MGI:1333819|Ensembl:ENSMUSG00000020799|Vega:OTTMUSG00000006103 +21691 Tel-rs2 MGI:MGI:99680 +21692 Tel-rs3 MGI:MGI:99679 +21693 Tel-rs4 MGI:MGI:893593 +21743 Inmt MGI:MGI:102963|Ensembl:ENSMUSG00000003477|Vega:OTTMUSG00000026997 +21744 Adad1 MGI:MGI:103258|Ensembl:ENSMUSG00000027719|Vega:OTTMUSG00000006613 +21745 Tep1 MGI:MGI:109573|Ensembl:ENSMUSG00000006281 +21748 Terc MGI:MGI:109558|Ensembl:ENSMUSG00000064796 +21749 Terf1 MGI:MGI:109634|Ensembl:ENSMUSG00000025925|Vega:OTTMUSG00000047984 +21750 Terf2 MGI:MGI:1195972|Ensembl:ENSMUSG00000031921|Vega:OTTMUSG00000032784 +21752 Tert MGI:MGI:1202709|Ensembl:ENSMUSG00000021611 +21753 Tes MGI:MGI:105081|Ensembl:ENSMUSG00000029552|Vega:OTTMUSG00000022490 +21754 Tesk1 MGI:MGI:1201675|Ensembl:ENSMUSG00000028458|Vega:OTTMUSG00000006821 +21755 Prss39 MGI:MGI:1270856|Ensembl:ENSMUSG00000026125|Vega:OTTMUSG00000049474 +21756 Prss40 MGI:MGI:1270857|Ensembl:ENSMUSG00000037529|Vega:OTTMUSG00000022629 +21757 Tet(5<12>)1Jic MGI:MGI:1196630 +21758 Tet(5<12>)1Jic MGI:MGI:1196615 +21761 Morf4l1 MGI:MGI:1096551|Ensembl:ENSMUSG00000062270|Vega:OTTMUSG00000046589 +21762 Psmd2 MGI:MGI:1096584|Ensembl:ENSMUSG00000006998|Vega:OTTMUSG00000036488 +21763 Tex2 MGI:MGI:102465|Ensembl:ENSMUSG00000040548|Vega:OTTMUSG00000003419 +21766 Tex261 MGI:MGI:1096575|Ensembl:ENSMUSG00000014748|Vega:OTTMUSG00000024125 +21767 Tex264 MGI:MGI:1096570|Ensembl:ENSMUSG00000040813|Vega:OTTMUSG00000049427 +21769 Zfand3 MGI:MGI:1096572|Ensembl:ENSMUSG00000044477 +21770 Ppp2r5d MGI:MGI:2388481|Ensembl:ENSMUSG00000059409 +21771 Utp4 MGI:MGI:1096573|Ensembl:ENSMUSG00000041438|Vega:OTTMUSG00000061929 +21778 Tex9 MGI:MGI:1201610|Ensembl:ENSMUSG00000090626|Vega:OTTMUSG00000044783 +21780 Tfam MGI:MGI:107810|Ensembl:ENSMUSG00000003923|Vega:OTTMUSG00000031039 +21781 Tfdp1 MGI:MGI:101934|Ensembl:ENSMUSG00000038482|Vega:OTTMUSG00000060903 +21782 Tfdp1-ps MGI:MGI:109560 +21784 Tff1 MGI:MGI:88135|Ensembl:ENSMUSG00000024032|Vega:OTTMUSG00000020096 +21785 Tff2 MGI:MGI:1306805|Ensembl:ENSMUSG00000024028|Vega:OTTMUSG00000020098 +21786 Tff3 MGI:MGI:104638|Ensembl:ENSMUSG00000024029|Vega:OTTMUSG00000020099 +21787 Tfg MGI:MGI:1338041|Ensembl:ENSMUSG00000022757|Vega:OTTMUSG00000026667 +21788 Tfpi MGI:MGI:1095418|Ensembl:ENSMUSG00000027082|Vega:OTTMUSG00000013407 +21789 Tfpi2 MGI:MGI:108543|Ensembl:ENSMUSG00000029664|Vega:OTTMUSG00000042627 +21802 Tgfa MGI:MGI:98724|Ensembl:ENSMUSG00000029999|Vega:OTTMUSG00000049992 +21803 Tgfb1 MGI:MGI:98725|Ensembl:ENSMUSG00000002603|Vega:OTTMUSG00000036027 +21804 Tgfb1i1 MGI:MGI:102784|Ensembl:ENSMUSG00000030782|Vega:OTTMUSG00000036582 +21807 Tsc22d1 MGI:MGI:109127|Ensembl:ENSMUSG00000022010|Vega:OTTMUSG00000026106 +21808 Tgfb2 MGI:MGI:98726|Ensembl:ENSMUSG00000039239|Vega:OTTMUSG00000050852 +21809 Tgfb3 MGI:MGI:98727|Ensembl:ENSMUSG00000021253 +21810 Tgfbi MGI:MGI:99959|Ensembl:ENSMUSG00000035493 +21812 Tgfbr1 MGI:MGI:98728|Ensembl:ENSMUSG00000007613|Vega:OTTMUSG00000006800 +21813 Tgfbr2 MGI:MGI:98729|Ensembl:ENSMUSG00000032440|Vega:OTTMUSG00000062871 +21814 Tgfbr3 MGI:MGI:104637|Ensembl:ENSMUSG00000029287|Vega:OTTMUSG00000028168 +21815 Tgif1 MGI:MGI:1194497|Ensembl:ENSMUSG00000047407|Vega:OTTMUSG00000031400 +21816 Tgm1 MGI:MGI:98730|Ensembl:ENSMUSG00000022218 +21817 Tgm2 MGI:MGI:98731|Ensembl:ENSMUSG00000037820|Vega:OTTMUSG00000015888 +21818 Tgm3 MGI:MGI:98732|Ensembl:ENSMUSG00000027401|Vega:OTTMUSG00000015499 +21819 Tg MGI:MGI:98733|Ensembl:ENSMUSG00000053469|Vega:OTTMUSG00000035631 +21821 Ift88 MGI:MGI:98715|Ensembl:ENSMUSG00000040040|Vega:OTTMUSG00000026733 +21822 Tgtp1 MGI:MGI:98734|Ensembl:ENSMUSG00000078922|Vega:OTTMUSG00000005527 +21823 Th MGI:MGI:98735|Ensembl:ENSMUSG00000000214|Vega:OTTMUSG00000018790 +21824 Thbd MGI:MGI:98736|Ensembl:ENSMUSG00000074743|Vega:OTTMUSG00000015710 +21825 Thbs1 MGI:MGI:98737|Ensembl:ENSMUSG00000040152|Vega:OTTMUSG00000015240 +21826 Thbs2 MGI:MGI:98738|Ensembl:ENSMUSG00000023885 +21827 Thbs3 MGI:MGI:98739|Ensembl:ENSMUSG00000028047|Vega:OTTMUSG00000030357 +21828 Thbs4 MGI:MGI:1101779|Ensembl:ENSMUSG00000021702|Vega:OTTMUSG00000036725 +21829 thd MGI:MGI:98740 +21830 Theg MGI:MGI:1338756|Ensembl:ENSMUSG00000020317|Vega:OTTMUSG00000034744 +21831 thf MGI:MGI:98741 +21832 Thpo MGI:MGI:101875|Ensembl:ENSMUSG00000022847|Vega:OTTMUSG00000021017 +21833 Thra MGI:MGI:98742|Ensembl:ENSMUSG00000058756|Vega:OTTMUSG00000006409 +21834 Thrb MGI:MGI:98743|Ensembl:ENSMUSG00000021779|Vega:OTTMUSG00000023243 +21835 Thrsp MGI:MGI:109126|Ensembl:ENSMUSG00000035686|Vega:OTTMUSG00000026137 +21836 Thse MGI:MGI:98745 +21837 Tht MGI:MGI:98746 +21838 Thy1 MGI:MGI:98747|Ensembl:ENSMUSG00000032011|Vega:OTTMUSG00000016734 +21840 ti MGI:MGI:98749 +21841 Tia1 MGI:MGI:107914|Ensembl:ENSMUSG00000071337|Vega:OTTMUSG00000022840 +21843 Tial1 MGI:MGI:107913|Ensembl:ENSMUSG00000030846|Vega:OTTMUSG00000025431 +21844 Tiam1 MGI:MGI:103306|Ensembl:ENSMUSG00000002489|Vega:OTTMUSG00000024287 +21846 Tie1 MGI:MGI:99906|Ensembl:ENSMUSG00000033191|Vega:OTTMUSG00000008793 +21847 Klf10 MGI:MGI:1101353|Ensembl:ENSMUSG00000037465 +21848 Trim24 MGI:MGI:109275|Ensembl:ENSMUSG00000029833|Vega:OTTMUSG00000030316 +21849 Trim28 MGI:MGI:109274|Ensembl:ENSMUSG00000005566|Vega:OTTMUSG00000023882 +21853 Timeless MGI:MGI:1321393|Ensembl:ENSMUSG00000039994|Vega:OTTMUSG00000024310 +21854 Timm17a MGI:MGI:1343131|Ensembl:ENSMUSG00000062580|Vega:OTTMUSG00000021888 +21855 Timm17b MGI:MGI:1343176|Ensembl:ENSMUSG00000031158|Vega:OTTMUSG00000018003 +21856 Timm44 MGI:MGI:1343262|Ensembl:ENSMUSG00000002949|Vega:OTTMUSG00000022227 +21857 Timp1 MGI:MGI:98752|Ensembl:ENSMUSG00000001131|Vega:OTTMUSG00000017184 +21858 Timp2 MGI:MGI:98753|Ensembl:ENSMUSG00000017466|Vega:OTTMUSG00000003883 +21859 Timp3 MGI:MGI:98754|Ensembl:ENSMUSG00000020044|Vega:OTTMUSG00000021184 +21863 tint MGI:MGI:98756 +21864 tip MGI:MGI:98757 +21869 Nkx2-1 MGI:MGI:108067|Ensembl:ENSMUSG00000001496|Vega:OTTMUSG00000044396 +21871 Atp6v0a2 MGI:MGI:104855|Ensembl:ENSMUSG00000038023|Vega:OTTMUSG00000054960 +21872 Tjp1 MGI:MGI:98759|Ensembl:ENSMUSG00000030516|Vega:OTTMUSG00000016466 +21873 Tjp2 MGI:MGI:1341872|Ensembl:ENSMUSG00000024812 +21874 tk MGI:MGI:98760 +21877 Tk1 MGI:MGI:98763|Ensembl:ENSMUSG00000025574|Vega:OTTMUSG00000003734 +21881 Tkt MGI:MGI:105992|Ensembl:ENSMUSG00000021957|Vega:OTTMUSG00000035018 +21884 Fabp9 MGI:MGI:1194881|Ensembl:ENSMUSG00000027528|Vega:OTTMUSG00000051461 +21885 Tle1 MGI:MGI:104636|Ensembl:ENSMUSG00000008305|Vega:OTTMUSG00000000333 +21886 Tle2 MGI:MGI:104635|Ensembl:ENSMUSG00000034771|Vega:OTTMUSG00000027831 +21887 Tle3 MGI:MGI:104634|Ensembl:ENSMUSG00000032280|Vega:OTTMUSG00000035108 +21888 Tle4 MGI:MGI:104633|Ensembl:ENSMUSG00000024642 +21892 Tll1 MGI:MGI:106923|Ensembl:ENSMUSG00000053626|Vega:OTTMUSG00000061183 +21893 Tlm MGI:MGI:98767 +21894 Tln1 MGI:MGI:1099832|Ensembl:ENSMUSG00000028465|Vega:OTTMUSG00000006961 +21897 Tlr1 MGI:MGI:1341295|Ensembl:ENSMUSG00000044827|Vega:OTTMUSG00000055138 +21898 Tlr4 MGI:MGI:96824|Ensembl:ENSMUSG00000039005|Vega:OTTMUSG00000000227 +21899 Tlr6 MGI:MGI:1341296|Ensembl:ENSMUSG00000051498|Vega:OTTMUSG00000055139 +21906 Otop1 MGI:MGI:2388363|Ensembl:ENSMUSG00000051596 +21907 Nr2e1 MGI:MGI:1100526|Ensembl:ENSMUSG00000019803|Vega:OTTMUSG00000019463 +21908 Tlx1 MGI:MGI:98769|Ensembl:ENSMUSG00000025215|Vega:OTTMUSG00000037553 +21909 Tlx2 MGI:MGI:1350935|Ensembl:ENSMUSG00000068327|Vega:OTTMUSG00000037556 +21911 tm MGI:MGI:98771 +21912 Tspan7 MGI:MGI:1298407|Ensembl:ENSMUSG00000058254|Vega:OTTMUSG00000016730 +21915 Dtymk MGI:MGI:108396|Ensembl:ENSMUSG00000026281|Vega:OTTMUSG00000022163 +21916 Tmod1 MGI:MGI:98775|Ensembl:ENSMUSG00000028328|Vega:OTTMUSG00000006835 +21917 Tmpo MGI:MGI:106920|Ensembl:ENSMUSG00000019961|Vega:OTTMUSG00000063806 +21922 Clec3b MGI:MGI:104540|Ensembl:ENSMUSG00000025784|Vega:OTTMUSG00000062841 +21923 Tnc MGI:MGI:101922|Ensembl:ENSMUSG00000028364|Vega:OTTMUSG00000000302 +21924 Tnnc1 MGI:MGI:98779|Ensembl:ENSMUSG00000091898|Vega:OTTMUSG00000035921 +21925 Tnnc2 MGI:MGI:98780|Ensembl:ENSMUSG00000017300|Vega:OTTMUSG00000001103 +21926 Tnf MGI:MGI:104798|Ensembl:ENSMUSG00000024401|Vega:OTTMUSG00000037196 +21927 Tnfaip1 MGI:MGI:104961|Ensembl:ENSMUSG00000017615|Vega:OTTMUSG00000000144 +21928 Tnfaip2 MGI:MGI:104960|Ensembl:ENSMUSG00000021281|Vega:OTTMUSG00000016690 +21929 Tnfaip3 MGI:MGI:1196377|Ensembl:ENSMUSG00000019850|Vega:OTTMUSG00000018149 +21930 Tnfaip6 MGI:MGI:1195266|Ensembl:ENSMUSG00000053475|Vega:OTTMUSG00000012436 +21933 Tnfrsf10b MGI:MGI:1341090|Ensembl:ENSMUSG00000022074 +21934 Tnfrsf11a MGI:MGI:1314891|Ensembl:ENSMUSG00000026321|Vega:OTTMUSG00000048968 +21935 Tnfrsf17 MGI:MGI:1343050|Ensembl:ENSMUSG00000022496|Vega:OTTMUSG00000027428 +21936 Tnfrsf18 MGI:MGI:894675|Ensembl:ENSMUSG00000041954|Vega:OTTMUSG00000010984 +21937 Tnfrsf1a MGI:MGI:1314884|Ensembl:ENSMUSG00000030341|Vega:OTTMUSG00000023806 +21938 Tnfrsf1b MGI:MGI:1314883|Ensembl:ENSMUSG00000028599|Vega:OTTMUSG00000010013 +21939 Cd40 MGI:MGI:88336|Ensembl:ENSMUSG00000017652|Vega:OTTMUSG00000016424 +21940 Cd27 MGI:MGI:88326|Ensembl:ENSMUSG00000030336|Vega:OTTMUSG00000024478 +21941 Tnfrsf8 MGI:MGI:99908|Ensembl:ENSMUSG00000028602|Vega:OTTMUSG00000010015 +21942 Tnfrsf9 MGI:MGI:1101059|Ensembl:ENSMUSG00000028965|Vega:OTTMUSG00000010241 +21943 Tnfsf11 MGI:MGI:1100089|Ensembl:ENSMUSG00000022015 +21944 Tnfsf12 MGI:MGI:1196259|Ensembl:ENSMUSG00000097328|Vega:OTTMUSG00000005999 +21945 Dedd MGI:MGI:1333874|Ensembl:ENSMUSG00000013973|Vega:OTTMUSG00000021703 +21946 Pglyrp1 MGI:MGI:1345092|Ensembl:ENSMUSG00000030413|Vega:OTTMUSG00000058432 +21947 Cd40lg MGI:MGI:88337|Ensembl:ENSMUSG00000031132|Vega:OTTMUSG00000017791 +21948 Cd70 MGI:MGI:1195273|Ensembl:ENSMUSG00000019489 +21949 Tnfsf8 MGI:MGI:88328|Ensembl:ENSMUSG00000028362|Vega:OTTMUSG00000000301 +21950 Tnfsf9 MGI:MGI:1101058|Ensembl:ENSMUSG00000035678 +21951 Tnks MGI:MGI:1341087|Ensembl:ENSMUSG00000031529|Vega:OTTMUSG00000061012 +21952 Tnni1 MGI:MGI:105073|Ensembl:ENSMUSG00000026418|Vega:OTTMUSG00000033121 +21953 Tnni2 MGI:MGI:105070|Ensembl:ENSMUSG00000031097|Vega:OTTMUSG00000018792 +21954 Tnni3 MGI:MGI:98783|Ensembl:ENSMUSG00000035458|Vega:OTTMUSG00000027089 +21955 Tnnt1 MGI:MGI:1333868|Ensembl:ENSMUSG00000064179|Vega:OTTMUSG00000036009 +21956 Tnnt2 MGI:MGI:104597|Ensembl:ENSMUSG00000026414|Vega:OTTMUSG00000049830 +21957 Tnnt3 MGI:MGI:109550|Ensembl:ENSMUSG00000061723|Vega:OTTMUSG00000018789 +21958 Tnp1 MGI:MGI:98784|Ensembl:ENSMUSG00000026182|Vega:OTTMUSG00000048231 +21959 Tnp2 MGI:MGI:98785|Ensembl:ENSMUSG00000043050 +21960 Tnr MGI:MGI:99516|Ensembl:ENSMUSG00000015829|Vega:OTTMUSG00000050612 +21961 Tns1 MGI:MGI:104552|Ensembl:ENSMUSG00000055322|Vega:OTTMUSG00000047279 +21968 Tom1 MGI:MGI:1338026|Ensembl:ENSMUSG00000042870|Vega:OTTMUSG00000062024 +21969 Top1 MGI:MGI:98788|Ensembl:ENSMUSG00000070544|Vega:OTTMUSG00000001178 +21973 Top2a MGI:MGI:98790|Ensembl:ENSMUSG00000020914|Vega:OTTMUSG00000006446 +21974 Top2b MGI:MGI:98791|Ensembl:ENSMUSG00000017485|Vega:OTTMUSG00000035016 +21975 Top3a MGI:MGI:1197527|Ensembl:ENSMUSG00000002814|Vega:OTTMUSG00000007746 +21976 Top3b MGI:MGI:1333803|Ensembl:ENSMUSG00000022779|Vega:OTTMUSG00000027460 +21977 tor MGI:MGI:98792 +21978 tp MGI:MGI:98793 +21979 Tp(Y)1Ct MGI:MGI:104286 +21981 Ppp1r13b MGI:MGI:1336199|Ensembl:ENSMUSG00000021285 +21982 Tmem165 MGI:MGI:894407|Ensembl:ENSMUSG00000029234|Vega:OTTMUSG00000026458 +21983 Tpbg MGI:MGI:1341264|Ensembl:ENSMUSG00000035274|Vega:OTTMUSG00000045041 +21984 Tpbpa MGI:MGI:98795|Ensembl:ENSMUSG00000033834 +21985 Tpd52 MGI:MGI:107749|Ensembl:ENSMUSG00000027506|Vega:OTTMUSG00000027689 +21987 Tpd52l1 MGI:MGI:1298386|Ensembl:ENSMUSG00000000296|Vega:OTTMUSG00000063862 +21990 Tph1 MGI:MGI:98796|Ensembl:ENSMUSG00000040046|Vega:OTTMUSG00000036091 +21991 Tpi1 MGI:MGI:98797|Ensembl:ENSMUSG00000023456|Vega:OTTMUSG00000017534 +22003 Tpm1 MGI:MGI:98809|Ensembl:ENSMUSG00000032366|Vega:OTTMUSG00000020411 +22004 Tpm2 MGI:MGI:98810|Ensembl:ENSMUSG00000028464|Vega:OTTMUSG00000006959 +22017 Tpmt MGI:MGI:98812|Ensembl:ENSMUSG00000021376|Vega:OTTMUSG00000024764 +22018 Tpo MGI:MGI:98813|Ensembl:ENSMUSG00000020673|Vega:OTTMUSG00000025268 +22019 Tpp2 MGI:MGI:102724|Ensembl:ENSMUSG00000041763|Vega:OTTMUSG00000046400 +22021 Tpst1 MGI:MGI:1298231|Ensembl:ENSMUSG00000034118|Vega:OTTMUSG00000027866 +22022 Tpst2 MGI:MGI:1309516|Ensembl:ENSMUSG00000029344|Vega:OTTMUSG00000024827 +22024 Crisp2 MGI:MGI:98815|Ensembl:ENSMUSG00000023930|Vega:OTTMUSG00000028301 +22025 Nr2c1 MGI:MGI:1352465|Ensembl:ENSMUSG00000005897|Vega:OTTMUSG00000022679 +22026 Nr2c2 MGI:MGI:1352466|Ensembl:ENSMUSG00000005893|Vega:OTTMUSG00000022788 +22027 Hsp90b1 MGI:MGI:98817|Ensembl:ENSMUSG00000020048|Vega:OTTMUSG00000020538 +22029 Traf1 MGI:MGI:101836|Ensembl:ENSMUSG00000026875|Vega:OTTMUSG00000012272 +22030 Traf2 MGI:MGI:101835|Ensembl:ENSMUSG00000026942|Vega:OTTMUSG00000012123 +22031 Traf3 MGI:MGI:108041|Ensembl:ENSMUSG00000021277|Vega:OTTMUSG00000031724 +22032 Traf4 MGI:MGI:1202880|Ensembl:ENSMUSG00000017386|Vega:OTTMUSG00000000106 +22033 Traf5 MGI:MGI:107548 +22034 Traf6 MGI:MGI:108072|Ensembl:ENSMUSG00000027164|Vega:OTTMUSG00000014586 +22035 Tnfsf10 MGI:MGI:107414|Ensembl:ENSMUSG00000039304|Vega:OTTMUSG00000037571 +22036 Traip MGI:MGI:1096377|Ensembl:ENSMUSG00000032586|Vega:OTTMUSG00000050792 +22037 Trap1a MGI:MGI:98818|Ensembl:ENSMUSG00000051257|Vega:OTTMUSG00000018704 +22038 Plscr1 MGI:MGI:893575|Ensembl:ENSMUSG00000032369|Vega:OTTMUSG00000023001 +22040 Trex1 MGI:MGI:1328317|Ensembl:ENSMUSG00000049734|Vega:OTTMUSG00000055468 +22041 Trf MGI:MGI:98821|Ensembl:ENSMUSG00000032554|Vega:OTTMUSG00000024707 +22042 Tfrc MGI:MGI:98822|Ensembl:ENSMUSG00000022797|Vega:OTTMUSG00000026922 +22044 Trh MGI:MGI:98823|Ensembl:ENSMUSG00000005892|Vega:OTTMUSG00000024415 +22045 Trhr MGI:MGI:98824|Ensembl:ENSMUSG00000038760 +22051 Trip6 MGI:MGI:1343458|Ensembl:ENSMUSG00000023348|Vega:OTTMUSG00000054535 +22052 trm MGI:MGI:98828 +22053 n-THgtg2 MGI:MGI:4413892 +22054 n-THgtg5 MGI:MGI:4413895 +22055 n-THgtg3 MGI:MGI:4413893 +22057 Tob1 MGI:MGI:1349721|Ensembl:ENSMUSG00000037573|Vega:OTTMUSG00000001711 +22059 Trp53 MGI:MGI:98834|Ensembl:ENSMUSG00000059552|Vega:OTTMUSG00000005982 +22060 Trp53-ps MGI:MGI:98835 +22061 Trp63 MGI:MGI:1330810|Ensembl:ENSMUSG00000022510|Vega:OTTMUSG00000021015 +22062 Trp73 MGI:MGI:1336991|Ensembl:ENSMUSG00000029026|Vega:OTTMUSG00000010497 +22063 Trpc1 MGI:MGI:109528|Ensembl:ENSMUSG00000032839|Vega:OTTMUSG00000047293 +22064 Trpc2 MGI:MGI:109527|Ensembl:ENSMUSG00000100254|Vega:OTTMUSG00000022733 +22065 Trpc3 MGI:MGI:109526|Ensembl:ENSMUSG00000027716|Vega:OTTMUSG00000006507 +22066 Trpc4 MGI:MGI:109525|Ensembl:ENSMUSG00000027748|Vega:OTTMUSG00000053764 +22067 Trpc5 MGI:MGI:109524|Ensembl:ENSMUSG00000041710|Vega:OTTMUSG00000018934 +22068 Trpc6 MGI:MGI:109523|Ensembl:ENSMUSG00000031997|Vega:OTTMUSG00000062337 +22069 n-TUtca2 MGI:MGI:4414022 +22070 Tpt1 MGI:MGI:104890|Ensembl:ENSMUSG00000060126|Vega:OTTMUSG00000018220 +22072 Prss2 MGI:MGI:102759|Ensembl:ENSMUSG00000057163|Vega:OTTMUSG00000026925 +22073 Prss3 MGI:MGI:102758|Ensembl:ENSMUSG00000071519|Vega:OTTMUSG00000051420 +22074 Try4 MGI:MGI:102757|Ensembl:ENSMUSG00000054106|Vega:OTTMUSG00000026910 +22078 Ts(1<13>)70H MGI:MGI:1314638 +22083 Ctr9 MGI:MGI:109345|Ensembl:ENSMUSG00000005609|Vega:OTTMUSG00000023898 +22084 Tsc2 MGI:MGI:102548|Ensembl:ENSMUSG00000002496 +22088 Tsg101 MGI:MGI:106581|Ensembl:ENSMUSG00000014402|Vega:OTTMUSG00000024345 +22089 Tsg101-ps MGI:MGI:1335078 +22092 Rsph1 MGI:MGI:1194909|Ensembl:ENSMUSG00000024033 +22094 Tshb MGI:MGI:98848|Ensembl:ENSMUSG00000027857|Vega:OTTMUSG00000054695 +22095 Tshr MGI:MGI:98849|Ensembl:ENSMUSG00000020963|Vega:OTTMUSG00000049745 +22097 Tsix MGI:MGI:1336196|Ensembl:ENSMUSG00000085715 +22099 Tsn MGI:MGI:109263|Ensembl:ENSMUSG00000026374|Vega:OTTMUSG00000049222 +22109 Tspy-ps MGI:MGI:1201688|Ensembl:ENSMUSG00000091749 +22110 Tspyl1 MGI:MGI:1298395|Ensembl:ENSMUSG00000047514|Vega:OTTMUSG00000020928 +22111 Tspyl-ps MGI:MGI:1298404 +22113 Phlda2 MGI:MGI:1202307|Ensembl:ENSMUSG00000010760|Vega:OTTMUSG00000024031 +22114 Tssk1 MGI:MGI:1347557|Ensembl:ENSMUSG00000041566|Vega:OTTMUSG00000050075 +22115 Tssk2 MGI:MGI:1347559|Ensembl:ENSMUSG00000045521 +22116 Tsks MGI:MGI:1347560|Ensembl:ENSMUSG00000059891|Vega:OTTMUSG00000031840 +22117 Tst MGI:MGI:98852|Ensembl:ENSMUSG00000044986 +22121 Rpl13a MGI:MGI:1351455|Ensembl:ENSMUSG00000074129|Vega:OTTMUSG00000016498 +22122 Tsta3 MGI:MGI:98857|Ensembl:ENSMUSG00000022570 +22123 Psmd3 MGI:MGI:98858|Ensembl:ENSMUSG00000017221|Vega:OTTMUSG00000006404 +22127 Tsx MGI:MGI:108118|Ensembl:ENSMUSG00000031329|Vega:OTTMUSG00000018249 +22129 Ttc3 MGI:MGI:1276539|Ensembl:ENSMUSG00000040785|Vega:OTTMUSG00000030295 +22130 Ttf1 MGI:MGI:105044|Ensembl:ENSMUSG00000026803|Vega:OTTMUSG00000011823 +22131 TTg(3;10)1Tex MGI:MGI:1316713 +22132 TTg(6;17)1N MGI:MGI:103926 +22133 TTg(6;17)1N MGI:MGI:103927 +22134 Tgoln1 MGI:MGI:105080|Ensembl:ENSMUSG00000056429|Vega:OTTMUSG00000037682 +22135 Tgoln2 MGI:MGI:105079 +22137 Ttk MGI:MGI:1194921|Ensembl:ENSMUSG00000038379|Vega:OTTMUSG00000044947 +22138 Ttn MGI:MGI:98864|Ensembl:ENSMUSG00000051747|Vega:OTTMUSG00000013134 +22139 Ttr MGI:MGI:98865|Ensembl:ENSMUSG00000061808 +22140 tu MGI:MGI:98867 +22141 Tub MGI:MGI:2651573|Ensembl:ENSMUSG00000031028|Vega:OTTMUSG00000030291 +22142 Tuba1a MGI:MGI:98869|Ensembl:ENSMUSG00000072235|Vega:OTTMUSG00000017053 +22143 Tuba1b MGI:MGI:107804|Ensembl:ENSMUSG00000023004|Vega:OTTMUSG00000017052 +22144 Tuba3a MGI:MGI:1095406|Ensembl:ENSMUSG00000067702|Vega:OTTMUSG00000056708 +22145 Tuba4a MGI:MGI:1095410|Ensembl:ENSMUSG00000026202|Vega:OTTMUSG00000048543 +22146 Tuba1c MGI:MGI:1095409|Ensembl:ENSMUSG00000043091 +22147 Tuba3b MGI:MGI:1095408|Ensembl:ENSMUSG00000067338|Vega:OTTMUSG00000022831 +22151 Tubb2a MGI:MGI:107861|Ensembl:ENSMUSG00000058672 +22152 Tubb3 MGI:MGI:107813|Ensembl:ENSMUSG00000062380|Vega:OTTMUSG00000027611 +22153 Tubb4a MGI:MGI:107848|Ensembl:ENSMUSG00000062591 +22154 Tubb5 MGI:MGI:107812|Ensembl:ENSMUSG00000001525|Vega:OTTMUSG00000026311 +22156 Tuft1 MGI:MGI:109572|Ensembl:ENSMUSG00000005968|Vega:OTTMUSG00000019566 +22157 Tulp1 MGI:MGI:109571|Ensembl:ENSMUSG00000037446|Vega:OTTMUSG00000024252 +22158 Tulp3 MGI:MGI:1329045|Ensembl:ENSMUSG00000001521|Vega:OTTMUSG00000022778 +22160 Twist1 MGI:MGI:98872|Ensembl:ENSMUSG00000035799 +22163 Tnfrsf4 MGI:MGI:104512|Ensembl:ENSMUSG00000029075|Vega:OTTMUSG00000010989 +22164 Tnfsf4 MGI:MGI:104511|Ensembl:ENSMUSG00000026700|Vega:OTTMUSG00000042461 +22165 Txk MGI:MGI:102960|Ensembl:ENSMUSG00000054892|Vega:OTTMUSG00000054700 +22166 Txn1 MGI:MGI:98874|Ensembl:ENSMUSG00000028367|Vega:OTTMUSG00000007384 +22167 Txn-ps1 MGI:MGI:98875 +22169 Cmpk2 MGI:MGI:99830|Ensembl:ENSMUSG00000020638 +22171 Tyms MGI:MGI:98878|Ensembl:ENSMUSG00000025747|Vega:OTTMUSG00000024722 +22172 Tyms-ps MGI:MGI:98879 +22173 Tyr MGI:MGI:98880|Ensembl:ENSMUSG00000004651|Vega:OTTMUSG00000059417 +22174 Tyro3 MGI:MGI:104294|Ensembl:ENSMUSG00000027298|Vega:OTTMUSG00000016527 +22177 Tyrobp MGI:MGI:1277211|Ensembl:ENSMUSG00000030579|Vega:OTTMUSG00000059315 +22178 Tyrp1 MGI:MGI:98881|Ensembl:ENSMUSG00000005994|Vega:OTTMUSG00000000391 +22183 Zrsr1 MGI:MGI:98885|Ensembl:ENSMUSG00000044068|Vega:OTTMUSG00000005268 +22184 Zrsr2 MGI:MGI:103287|Ensembl:ENSMUSG00000031370|Vega:OTTMUSG00000019507 +22185 U2af2 MGI:MGI:98886|Ensembl:ENSMUSG00000030435|Vega:OTTMUSG00000059861 +22186 Uba52 MGI:MGI:98887|Ensembl:ENSMUSG00000090137|Vega:OTTMUSG00000033543 +22187 Ubb MGI:MGI:98888|Ensembl:ENSMUSG00000019505|Vega:OTTMUSG00000005857 +22190 Ubc MGI:MGI:98889|Ensembl:ENSMUSG00000008348|Vega:OTTMUSG00000034016 +22192 Ube2m MGI:MGI:108278|Ensembl:ENSMUSG00000005575|Vega:OTTMUSG00000023220 +22193 Ube2e3 MGI:MGI:107412|Ensembl:ENSMUSG00000027011|Vega:OTTMUSG00000016715 +22194 Ube2e1 MGI:MGI:107411|Ensembl:ENSMUSG00000021774|Vega:OTTMUSG00000028840 +22195 Ube2l3 MGI:MGI:109240|Ensembl:ENSMUSG00000038965|Vega:OTTMUSG00000025066 +22196 Ube2i MGI:MGI:107365|Ensembl:ENSMUSG00000015120|Vega:OTTMUSG00000037656 +22200 Uba3 MGI:MGI:1341217|Ensembl:ENSMUSG00000030061|Vega:OTTMUSG00000057821 +22201 Uba1 MGI:MGI:98890|Ensembl:ENSMUSG00000001924|Vega:OTTMUSG00000017113 +22202 Uba1y MGI:MGI:98891|Ensembl:ENSMUSG00000069053|Vega:OTTMUSG00000045273 +22203 Uba1y-ps1 MGI:MGI:98892 +22204 Uba1y-ps2 MGI:MGI:102958 +22209 Ube2a MGI:MGI:102959|Ensembl:ENSMUSG00000016308|Vega:OTTMUSG00000017105 +22210 Ube2b MGI:MGI:102944|Ensembl:ENSMUSG00000020390|Vega:OTTMUSG00000005613 +22213 Ube2g2 MGI:MGI:1343188|Ensembl:ENSMUSG00000009293|Vega:OTTMUSG00000038229 +22214 Ube2h MGI:MGI:104632|Ensembl:ENSMUSG00000039159|Vega:OTTMUSG00000014347 +22215 Ube3a MGI:MGI:105098|Ensembl:ENSMUSG00000025326|Vega:OTTMUSG00000055999 +22217 Usp12 MGI:MGI:1270128|Ensembl:ENSMUSG00000029640|Vega:OTTMUSG00000024588 +22218 Sumo1 MGI:MGI:1197010|Ensembl:ENSMUSG00000026021|Vega:OTTMUSG00000022159 +22221 Ubp1 MGI:MGI:104889|Ensembl:ENSMUSG00000009741|Vega:OTTMUSG00000062511 +22222 Ubr1 MGI:MGI:1277977|Ensembl:ENSMUSG00000027272|Vega:OTTMUSG00000015780 +22223 Uchl1 MGI:MGI:103149|Ensembl:ENSMUSG00000029223|Vega:OTTMUSG00000042268 +22224 Usp10 MGI:MGI:894652|Ensembl:ENSMUSG00000031826|Vega:OTTMUSG00000026199 +22225 Usp5 MGI:MGI:1347343|Ensembl:ENSMUSG00000038429|Vega:OTTMUSG00000027216 +22226 Ucn MGI:MGI:1276123|Ensembl:ENSMUSG00000038676|Vega:OTTMUSG00000022485 +22227 Ucp1 MGI:MGI:98894|Ensembl:ENSMUSG00000031710|Vega:OTTMUSG00000061515 +22228 Ucp2 MGI:MGI:109354|Ensembl:ENSMUSG00000033685|Vega:OTTMUSG00000022804 +22229 Ucp3 MGI:MGI:1099787|Ensembl:ENSMUSG00000032942|Vega:OTTMUSG00000022800 +22230 Ufd1 MGI:MGI:109353|Ensembl:ENSMUSG00000005262|Vega:OTTMUSG00000036274 +22232 Slc35a2 MGI:MGI:1345297|Ensembl:ENSMUSG00000031156|Vega:OTTMUSG00000018002 +22234 Ugcg MGI:MGI:1332243|Ensembl:ENSMUSG00000028381|Vega:OTTMUSG00000007645 +22235 Ugdh MGI:MGI:1306785|Ensembl:ENSMUSG00000029201|Vega:OTTMUSG00000028398 +22236 Ugt1a2 MGI:MGI:3576049|Ensembl:ENSMUSG00000090171|Vega:OTTMUSG00000020805 +22238 Ugt2b5 MGI:MGI:98900|Ensembl:ENSMUSG00000054630|Vega:OTTMUSG00000026780 +22239 Ugt8a MGI:MGI:109522|Ensembl:ENSMUSG00000032854|Vega:OTTMUSG00000052622 +22240 Dpysl3 MGI:MGI:1349762|Ensembl:ENSMUSG00000024501|Vega:OTTMUSG00000029636 +22241 Ulk1 MGI:MGI:1270126|Ensembl:ENSMUSG00000029512|Vega:OTTMUSG00000054223 +22242 Umod MGI:MGI:102674|Ensembl:ENSMUSG00000030963|Vega:OTTMUSG00000059102 +22245 Uck1 MGI:MGI:98904|Ensembl:ENSMUSG00000002550|Vega:OTTMUSG00000012955 +22247 Umps MGI:MGI:1298388|Ensembl:ENSMUSG00000022814|Vega:OTTMUSG00000031003 +22248 Unc119 MGI:MGI:1328357|Ensembl:ENSMUSG00000002058|Vega:OTTMUSG00000000135 +22249 Unc13b MGI:MGI:1342278|Ensembl:ENSMUSG00000028456|Vega:OTTMUSG00000006761 +22253 Unc5c MGI:MGI:1095412|Ensembl:ENSMUSG00000059921|Vega:OTTMUSG00000025311 +22255 Uncx MGI:MGI:108013|Ensembl:ENSMUSG00000029546|Vega:OTTMUSG00000038278 +22256 Ung MGI:MGI:109352|Ensembl:ENSMUSG00000029591|Vega:OTTMUSG00000013709 +22258 Usp4 MGI:MGI:98905|Ensembl:ENSMUSG00000032612|Vega:OTTMUSG00000050819 +22259 Nr1h3 MGI:MGI:1352462|Ensembl:ENSMUSG00000002108|Vega:OTTMUSG00000014415 +22260 Nr1h2 MGI:MGI:1352463|Ensembl:ENSMUSG00000060601|Vega:OTTMUSG00000023074 +22261 uns MGI:MGI:98906 +22262 Uox MGI:MGI:98907|Ensembl:ENSMUSG00000028186|Vega:OTTMUSG00000029704 +22264 Prap1 MGI:MGI:893573|Ensembl:ENSMUSG00000025467|Vega:OTTMUSG00000027344 +22268 Upk1b MGI:MGI:98912|Ensembl:ENSMUSG00000049436 +22269 Upk2 MGI:MGI:98913|Ensembl:ENSMUSG00000041523|Vega:OTTMUSG00000063306 +22270 Upk3a MGI:MGI:98914|Ensembl:ENSMUSG00000022435 +22271 Upp1 MGI:MGI:1097668|Ensembl:ENSMUSG00000020407|Vega:OTTMUSG00000005150 +22272 Uqcrq MGI:MGI:107807|Ensembl:ENSMUSG00000044894|Vega:OTTMUSG00000000054 +22273 Uqcrc1 MGI:MGI:107876|Ensembl:ENSMUSG00000025651|Vega:OTTMUSG00000051043 +22274 ur MGI:MGI:98915 +22275 Urod MGI:MGI:98916|Ensembl:ENSMUSG00000028684|Vega:OTTMUSG00000009782 +22276 Uros MGI:MGI:98917|Ensembl:ENSMUSG00000030979|Vega:OTTMUSG00000025682 +22277 us MGI:MGI:98918 +22278 Usf1 MGI:MGI:99542|Ensembl:ENSMUSG00000026641|Vega:OTTMUSG00000030990 +22282 Usf2 MGI:MGI:99961|Ensembl:ENSMUSG00000058239|Vega:OTTMUSG00000036026 +22283 Ush2a MGI:MGI:1341292|Ensembl:ENSMUSG00000026609|Vega:OTTMUSG00000018252 +22284 Usp9x MGI:MGI:894681|Ensembl:ENSMUSG00000031010|Vega:OTTMUSG00000017076 +22286 Utf1 MGI:MGI:1276125|Ensembl:ENSMUSG00000047751|Vega:OTTMUSG00000042369 +22287 Scgb1a1 MGI:MGI:98919|Ensembl:ENSMUSG00000024653|Vega:OTTMUSG00000035954 +22288 Utrn MGI:MGI:104631|Ensembl:ENSMUSG00000019820 +22289 Kdm6a MGI:MGI:1095419|Ensembl:ENSMUSG00000037369|Vega:OTTMUSG00000016960 +22290 Uty MGI:MGI:894810|Ensembl:ENSMUSG00000068457|Vega:OTTMUSG00000032814 +22293 Slc45a2 MGI:MGI:2153040|Ensembl:ENSMUSG00000022243|Vega:OTTMUSG00000026270 +22294 Uxt MGI:MGI:1277988|Ensembl:ENSMUSG00000001134|Vega:OTTMUSG00000017183 +22295 Cdh23 MGI:MGI:1890219|Ensembl:ENSMUSG00000012819|Vega:OTTMUSG00000017511 +22296 Vmn1r51 MGI:MGI:1333759|Ensembl:ENSMUSG00000062818|Vega:OTTMUSG00000037451 +22297 Vmn1r45 MGI:MGI:1333762|Ensembl:ENSMUSG00000044248|Vega:OTTMUSG00000037443 +22300 Vmn2r123 MGI:MGI:1316688 +22301 Vmn2r89 MGI:MGI:1316707|Ensembl:ENSMUSG00000070448|Vega:OTTMUSG00000033229 +22305 Vmn2r37 MGI:MGI:1316711|Ensembl:ENSMUSG00000066828|Vega:OTTMUSG00000037972 +22306 Vmn2r30 MGI:MGI:1316729|Ensembl:ENSMUSG00000070847|Vega:OTTMUSG00000037805 +22307 Vmn2r10 MGI:MGI:1316730|Ensembl:ENSMUSG00000067010|Vega:OTTMUSG00000039858 +22308 Vmn2r122 MGI:MGI:1316661|Ensembl:ENSMUSG00000096730 +22310 Vmn2r42 MGI:MGI:1316666|Ensembl:ENSMUSG00000070844|Vega:OTTMUSG00000042465 +22311 Vmn2r32 MGI:MGI:1316696|Ensembl:ENSMUSG00000096743|Vega:OTTMUSG00000037837 +22312 Vmn2r107 MGI:MGI:1316664|Ensembl:ENSMUSG00000056910|Vega:OTTMUSG00000039776 +22313 Vmn2r104 MGI:MGI:1316665|Ensembl:ENSMUSG00000090315|Vega:OTTMUSG00000039769 +22314 Vmn2r-ps159 MGI:MGI:1316735|Ensembl:ENSMUSG00000057021 +22317 Vamp1 MGI:MGI:1313276|Ensembl:ENSMUSG00000030337|Vega:OTTMUSG00000022687 +22318 Vamp2 MGI:MGI:1313277|Ensembl:ENSMUSG00000020894|Vega:OTTMUSG00000005972 +22319 Vamp3 MGI:MGI:1321389|Ensembl:ENSMUSG00000028955|Vega:OTTMUSG00000010239 +22320 Vamp8 MGI:MGI:1336882|Ensembl:ENSMUSG00000050732|Vega:OTTMUSG00000022685 +22321 Vars MGI:MGI:90675|Ensembl:ENSMUSG00000007029|Vega:OTTMUSG00000037142 +22323 Vasp MGI:MGI:109268|Ensembl:ENSMUSG00000030403|Vega:OTTMUSG00000024627 +22324 Vav1 MGI:MGI:98923|Ensembl:ENSMUSG00000034116|Vega:OTTMUSG00000036994 +22325 Vav2 MGI:MGI:102718|Ensembl:ENSMUSG00000009621|Vega:OTTMUSG00000012034 +22326 Vax1 MGI:MGI:1277163|Ensembl:ENSMUSG00000006270|Vega:OTTMUSG00000037558 +22327 Vbp1 MGI:MGI:1333804|Ensembl:ENSMUSG00000031197|Vega:OTTMUSG00000020873 +22328 vc MGI:MGI:98925 +22329 Vcam1 MGI:MGI:98926|Ensembl:ENSMUSG00000027962|Vega:OTTMUSG00000054446 +22330 Vcl MGI:MGI:98927|Ensembl:ENSMUSG00000021823 +22333 Vdac1 MGI:MGI:106919|Ensembl:ENSMUSG00000020402|Vega:OTTMUSG00000005626 +22334 Vdac2 MGI:MGI:106915|Ensembl:ENSMUSG00000021771|Vega:OTTMUSG00000016381 +22335 Vdac3 MGI:MGI:106922|Ensembl:ENSMUSG00000008892|Vega:OTTMUSG00000060891 +22336 Vdac3-ps1 MGI:MGI:1270159 +22337 Vdr MGI:MGI:103076|Ensembl:ENSMUSG00000022479|Vega:OTTMUSG00000026431 +22339 Vegfa MGI:MGI:103178|Ensembl:ENSMUSG00000023951|Vega:OTTMUSG00000016285 +22340 Vegfb MGI:MGI:106199|Ensembl:ENSMUSG00000024962|Vega:OTTMUSG00000033015 +22341 Vegfc MGI:MGI:109124|Ensembl:ENSMUSG00000031520|Vega:OTTMUSG00000060617 +22342 Lin7b MGI:MGI:1330858|Ensembl:ENSMUSG00000003872|Vega:OTTMUSG00000016518 +22343 Lin7c MGI:MGI:1330839|Ensembl:ENSMUSG00000027162|Vega:OTTMUSG00000015123 +22344 Vezf1 MGI:MGI:1313291|Ensembl:ENSMUSG00000018377|Vega:OTTMUSG00000001479 +22346 Vhl MGI:MGI:103223|Ensembl:ENSMUSG00000033933|Vega:OTTMUSG00000024147 +22348 Slc32a1 MGI:MGI:1194488|Ensembl:ENSMUSG00000037771|Vega:OTTMUSG00000015925 +22349 Vil1 MGI:MGI:98930|Ensembl:ENSMUSG00000026175|Vega:OTTMUSG00000021741 +22350 Ezr MGI:MGI:98931|Ensembl:ENSMUSG00000052397|Vega:OTTMUSG00000018216 +22351 Vill MGI:MGI:1201781|Ensembl:ENSMUSG00000038775|Vega:OTTMUSG00000033841 +22352 Vim MGI:MGI:98932|Ensembl:ENSMUSG00000026728|Vega:OTTMUSG00000011231 +22353 Vip MGI:MGI:98933|Ensembl:ENSMUSG00000019772|Vega:OTTMUSG00000063563 +22354 Vipr1 MGI:MGI:109272|Ensembl:ENSMUSG00000032528|Vega:OTTMUSG00000027442 +22355 Vipr2 MGI:MGI:107166|Ensembl:ENSMUSG00000011171|Vega:OTTMUSG00000040123 +22359 Vldlr MGI:MGI:98935|Ensembl:ENSMUSG00000024924|Vega:OTTMUSG00000035962 +22360 Nrsn1 MGI:MGI:894662|Ensembl:ENSMUSG00000048978|Vega:OTTMUSG00000000740 +22361 Vnn1 MGI:MGI:108395|Ensembl:ENSMUSG00000037440|Vega:OTTMUSG00000044612 +22362 Vpreb1 MGI:MGI:98936|Ensembl:ENSMUSG00000059305|Vega:OTTMUSG00000017055 +22363 Vpreb2 MGI:MGI:98937|Ensembl:ENSMUSG00000059280 +22364 Vpreb3 MGI:MGI:98938|Ensembl:ENSMUSG00000000903|Vega:OTTMUSG00000016465 +22365 Vps45 MGI:MGI:891965|Ensembl:ENSMUSG00000015747|Vega:OTTMUSG00000022191 +22367 Vrk1 MGI:MGI:1261847|Ensembl:ENSMUSG00000021115 +22368 Trpv2 MGI:MGI:1341836|Ensembl:ENSMUSG00000018507|Vega:OTTMUSG00000005868 +22370 Vtn MGI:MGI:98940|Ensembl:ENSMUSG00000017344|Vega:OTTMUSG00000000143 +22371 Vwf MGI:MGI:98941|Ensembl:ENSMUSG00000001930|Vega:OTTMUSG00000022190 +22372 wal MGI:MGI:98942 +22373 Wap MGI:MGI:98943|Ensembl:ENSMUSG00000000381|Vega:OTTMUSG00000005118 +22375 Wars MGI:MGI:104630|Ensembl:ENSMUSG00000021266|Vega:OTTMUSG00000034952 +22376 Was MGI:MGI:105059|Ensembl:ENSMUSG00000031165|Vega:OTTMUSG00000018093 +22377 Wbp1 MGI:MGI:104710|Ensembl:ENSMUSG00000030035|Vega:OTTMUSG00000024274 +22378 Wbp2 MGI:MGI:104709|Ensembl:ENSMUSG00000034341|Vega:OTTMUSG00000003690 +22379 Fmnl3 MGI:MGI:109569|Ensembl:ENSMUSG00000023008|Vega:OTTMUSG00000028048 +22380 Wbp4 MGI:MGI:109568|Ensembl:ENSMUSG00000022023 +22381 Tceal9 MGI:MGI:109567|Ensembl:ENSMUSG00000042712|Vega:OTTMUSG00000018694 +22384 Eif4h MGI:MGI:1341822|Ensembl:ENSMUSG00000040731|Vega:OTTMUSG00000055761 +22385 Baz1b MGI:MGI:1353499|Ensembl:ENSMUSG00000002748|Vega:OTTMUSG00000017117 +22387 wd MGI:MGI:98946 +22388 Wdr1 MGI:MGI:1337100|Ensembl:ENSMUSG00000005103|Vega:OTTMUSG00000056283 +22390 Wee1 MGI:MGI:103075|Ensembl:ENSMUSG00000031016|Vega:OTTMUSG00000060172 +22392 wfd MGI:MGI:1310006 +22393 Wfs1 MGI:MGI:1328355|Ensembl:ENSMUSG00000039474|Vega:OTTMUSG00000035647 +22394 wh MGI:MGI:98949 +22401 Zmat3 MGI:MGI:1195270|Ensembl:ENSMUSG00000027663|Vega:OTTMUSG00000022152 +22402 Wisp1 MGI:MGI:1197008|Ensembl:ENSMUSG00000005124|Vega:OTTMUSG00000028045 +22403 Wisp2 MGI:MGI:1328326|Ensembl:ENSMUSG00000027656|Vega:OTTMUSG00000001174 +22404 Wiz MGI:MGI:1332638|Ensembl:ENSMUSG00000024050|Vega:OTTMUSG00000035221 +22406 Wld MGI:MGI:98952 +22407 wn MGI:MGI:1343183 +22408 Wnt1 MGI:MGI:98953|Ensembl:ENSMUSG00000022997|Vega:OTTMUSG00000020981 +22409 Wnt10a MGI:MGI:108071|Ensembl:ENSMUSG00000026167|Vega:OTTMUSG00000020879 +22410 Wnt10b MGI:MGI:108061|Ensembl:ENSMUSG00000022996 +22411 Wnt11 MGI:MGI:101948|Ensembl:ENSMUSG00000015957|Vega:OTTMUSG00000036052 +22412 Wnt9b MGI:MGI:1197020|Ensembl:ENSMUSG00000018486|Vega:OTTMUSG00000003017 +22413 Wnt2 MGI:MGI:98954|Ensembl:ENSMUSG00000010797|Vega:OTTMUSG00000024176 +22414 Wnt2b MGI:MGI:1261834|Ensembl:ENSMUSG00000027840|Vega:OTTMUSG00000053152 +22415 Wnt3 MGI:MGI:98955|Ensembl:ENSMUSG00000000125|Vega:OTTMUSG00000003018 +22416 Wnt3a MGI:MGI:98956|Ensembl:ENSMUSG00000009900|Vega:OTTMUSG00000005791 +22417 Wnt4 MGI:MGI:98957|Ensembl:ENSMUSG00000036856|Vega:OTTMUSG00000009828 +22418 Wnt5a MGI:MGI:98958|Ensembl:ENSMUSG00000021994|Vega:OTTMUSG00000021010 +22419 Wnt5b MGI:MGI:98959|Ensembl:ENSMUSG00000030170|Vega:OTTMUSG00000027047 +22420 Wnt6 MGI:MGI:98960|Ensembl:ENSMUSG00000033227|Vega:OTTMUSG00000048253 +22421 Wnt7a MGI:MGI:98961|Ensembl:ENSMUSG00000030093|Vega:OTTMUSG00000022158 +22422 Wnt7b MGI:MGI:98962|Ensembl:ENSMUSG00000022382 +22423 Wnt8b MGI:MGI:109485|Ensembl:ENSMUSG00000036961 +22427 Wrn MGI:MGI:109635|Ensembl:ENSMUSG00000031583|Vega:OTTMUSG00000060957 +22428 Dctn6 MGI:MGI:1343154|Ensembl:ENSMUSG00000031516|Vega:OTTMUSG00000031286 +22429 wsnp MGI:MGI:1276119 +22431 Wt1 MGI:MGI:98968|Ensembl:ENSMUSG00000016458|Vega:OTTMUSG00000014987 +22433 Xbp1 MGI:MGI:98970|Ensembl:ENSMUSG00000020484|Vega:OTTMUSG00000006338 +22436 Xdh MGI:MGI:98973|Ensembl:ENSMUSG00000024066 +22437 Xirp1 MGI:MGI:1333878|Ensembl:ENSMUSG00000079243|Vega:OTTMUSG00000062520 +22439 Xk MGI:MGI:103569|Ensembl:ENSMUSG00000015342|Vega:OTTMUSG00000016888 +22441 Xlr MGI:MGI:98976|Ensembl:ENSMUSG00000054626|Vega:OTTMUSG00000017392 +22445 Xlr3a MGI:MGI:109506|Ensembl:ENSMUSG00000057836|Vega:OTTMUSG00000017651 +22446 Xlr3c MGI:MGI:3047103|Ensembl:ENSMUSG00000058147|Vega:OTTMUSG00000017650 +22526 Gm4836 MGI:MGI:3809202|Ensembl:ENSMUSG00000094624|Vega:OTTMUSG00000017529 +22532 Xmv14 MGI:MGI:99060 +22547 Xmv28 MGI:MGI:99075 +22564 Xmv44 MGI:MGI:99092 +22586 Xmv8 MGI:MGI:99131 +22587 Xmv9 MGI:MGI:99133 +22588 xn MGI:MGI:99134 +22589 Atrx MGI:MGI:103067|Ensembl:ENSMUSG00000031229|Vega:OTTMUSG00000018268 +22590 Xpa MGI:MGI:99135|Ensembl:ENSMUSG00000028329|Vega:OTTMUSG00000006889 +22591 Xpc MGI:MGI:103557|Ensembl:ENSMUSG00000030094|Vega:OTTMUSG00000024133 +22592 Ercc5 MGI:MGI:103582|Ensembl:ENSMUSG00000026048|Vega:OTTMUSG00000021431 +22594 Xrcc1 MGI:MGI:99137|Ensembl:ENSMUSG00000051768|Vega:OTTMUSG00000058221 +22596 Xrcc5 MGI:MGI:104517|Ensembl:ENSMUSG00000026187 +22598 Slc6a18 MGI:MGI:1336892|Ensembl:ENSMUSG00000021612 +22599 Slc6a20b MGI:MGI:1336891|Ensembl:ENSMUSG00000025243|Vega:OTTMUSG00000036106 +22601 Yap1 MGI:MGI:103262|Ensembl:ENSMUSG00000053110|Vega:OTTMUSG00000038037 +22602 YB10 MGI:MGI:99141 +22608 Ybx1 MGI:MGI:99146|Ensembl:ENSMUSG00000028639|Vega:OTTMUSG00000009259 +22609 Ybx1-ps1 MGI:MGI:99469 +22612 Yes1 MGI:MGI:99147|Ensembl:ENSMUSG00000014932|Vega:OTTMUSG00000055350 +22619 Siae MGI:MGI:104803|Ensembl:ENSMUSG00000001942|Vega:OTTMUSG00000027448 +22625 Map3k19 MGI:MGI:1203481|Ensembl:ENSMUSG00000051590|Vega:OTTMUSG00000045399 +22626 Slc23a3 MGI:MGI:104516|Ensembl:ENSMUSG00000026205|Vega:OTTMUSG00000048447 +22627 Ywhae MGI:MGI:894689|Ensembl:ENSMUSG00000020849|Vega:OTTMUSG00000006219 +22628 Ywhag MGI:MGI:108109|Ensembl:ENSMUSG00000051391|Vega:OTTMUSG00000016297 +22629 Ywhah MGI:MGI:109194|Ensembl:ENSMUSG00000018965|Vega:OTTMUSG00000016346 +22630 Ywhaq MGI:MGI:891963|Ensembl:ENSMUSG00000076432|Vega:OTTMUSG00000016335 +22631 Ywhaz MGI:MGI:109484|Ensembl:ENSMUSG00000022285|Vega:OTTMUSG00000017005 +22632 Yy1 MGI:MGI:99150|Ensembl:ENSMUSG00000021264|Vega:OTTMUSG00000017257 +22633 z MGI:MGI:99151 +22634 Plagl1 MGI:MGI:1100874|Ensembl:ENSMUSG00000019817|Vega:OTTMUSG00000031215 +22635 Zan MGI:MGI:106656|Ensembl:ENSMUSG00000079173|Vega:OTTMUSG00000030088 +22637 Zap70 MGI:MGI:99613|Ensembl:ENSMUSG00000026117|Vega:OTTMUSG00000049481 +22639 Zfa-ps MGI:MGI:99153|Ensembl:ENSMUSG00000049576 +22640 Zfp1 MGI:MGI:99154|Ensembl:ENSMUSG00000055835|Vega:OTTMUSG00000061793 +22642 Zbtb17 MGI:MGI:107410|Ensembl:ENSMUSG00000006215|Vega:OTTMUSG00000010292 +22643 Zfp101 MGI:MGI:107547|Ensembl:ENSMUSG00000055240|Vega:OTTMUSG00000037198 +22644 Rnf103 MGI:MGI:109483|Ensembl:ENSMUSG00000052656|Vega:OTTMUSG00000023991 +22646 Zfp105 MGI:MGI:1277119|Ensembl:ENSMUSG00000057895|Vega:OTTMUSG00000031821 +22648 Zfp11 MGI:MGI:99156|Ensembl:ENSMUSG00000051034|Vega:OTTMUSG00000022618 +22651 Zfp125 MGI:MGI:1336211 +22652 Mkrn3 MGI:MGI:2181178|Ensembl:ENSMUSG00000070527|Vega:OTTMUSG00000059566 +22654 Zfp13 MGI:MGI:99159|Ensembl:ENSMUSG00000062012 +22658 Pcgf2 MGI:MGI:99161|Ensembl:ENSMUSG00000018537|Vega:OTTMUSG00000002751 +22661 Zfp148 MGI:MGI:1332234|Ensembl:ENSMUSG00000022811 +22666 Zbtb14 MGI:MGI:1195345|Ensembl:ENSMUSG00000049672|Vega:OTTMUSG00000021835 +22668 Sf1 MGI:MGI:1095403|Ensembl:ENSMUSG00000024949|Vega:OTTMUSG00000018615 +22670 Trim26 MGI:MGI:1337056|Ensembl:ENSMUSG00000024457|Vega:OTTMUSG00000033434 +22671 Rnf112 MGI:MGI:106611|Ensembl:ENSMUSG00000010086|Vega:OTTMUSG00000005832 +22673 Zfp185 MGI:MGI:108095|Ensembl:ENSMUSG00000031351|Vega:OTTMUSG00000017674 +22678 Zfp2 MGI:MGI:99167|Ensembl:ENSMUSG00000049321|Vega:OTTMUSG00000007892 +22680 Zfp207 MGI:MGI:1340045|Ensembl:ENSMUSG00000017421|Vega:OTTMUSG00000000221 +22682 Zfand5 MGI:MGI:1278334|Ensembl:ENSMUSG00000024750|Vega:OTTMUSG00000032984 +22685 Zfp239 MGI:MGI:1306812|Ensembl:ENSMUSG00000042097|Vega:OTTMUSG00000022149 +22687 Zpr1 MGI:MGI:1330262|Ensembl:ENSMUSG00000032078|Vega:OTTMUSG00000021886 +22688 Zfp26 MGI:MGI:99173|Ensembl:ENSMUSG00000063108|Vega:OTTMUSG00000034227 +22689 Zfp27 MGI:MGI:99174|Ensembl:ENSMUSG00000062040|Vega:OTTMUSG00000029143 +22690 Zfp28 MGI:MGI:99175|Ensembl:ENSMUSG00000062861|Vega:OTTMUSG00000060101 +22691 Zscan2 MGI:MGI:99176|Ensembl:ENSMUSG00000038797|Vega:OTTMUSG00000027313 +22693 Zfp30 MGI:MGI:99178|Ensembl:ENSMUSG00000047473|Vega:OTTMUSG00000022380 +22694 Zfp35 MGI:MGI:99179|Ensembl:ENSMUSG00000063281|Vega:OTTMUSG00000033724 +22695 Zfp36 MGI:MGI:99180|Ensembl:ENSMUSG00000044786|Vega:OTTMUSG00000021115 +22696 Zfp37 MGI:MGI:99181|Ensembl:ENSMUSG00000028389|Vega:OTTMUSG00000000308 +22697 Zscan21 MGI:MGI:99182|Ensembl:ENSMUSG00000037017|Vega:OTTMUSG00000022636 +22698 Zfp39 MGI:MGI:99183|Ensembl:ENSMUSG00000037001|Vega:OTTMUSG00000005758 +22700 Zfp40 MGI:MGI:99185|Ensembl:ENSMUSG00000002617|Vega:OTTMUSG00000028083 +22701 Zfp41 MGI:MGI:99186|Ensembl:ENSMUSG00000047003|Vega:OTTMUSG00000033425 +22702 Zfp42 MGI:MGI:99187|Ensembl:ENSMUSG00000051176|Vega:OTTMUSG00000061169 +22703 Zfp42-ps1 MGI:MGI:1334259 +22704 Zfp46 MGI:MGI:99192|Ensembl:ENSMUSG00000051351|Vega:OTTMUSG00000009866 +22709 Zfp51 MGI:MGI:99198|Ensembl:ENSMUSG00000023892 +22710 Zfp52 MGI:MGI:99199|Ensembl:ENSMUSG00000051341 +22712 Zfp54 MGI:MGI:99201|Ensembl:ENSMUSG00000023882|Vega:OTTMUSG00000036850 +22715 Zfp57 MGI:MGI:99204|Ensembl:ENSMUSG00000036036|Vega:OTTMUSG00000037387 +22717 Zfp59 MGI:MGI:99206|Ensembl:ENSMUSG00000078779|Vega:OTTMUSG00000058618 +22718 Zfp60 MGI:MGI:99207|Ensembl:ENSMUSG00000037640|Vega:OTTMUSG00000022375 +22719 Zfp61 MGI:MGI:99663|Ensembl:ENSMUSG00000050605|Vega:OTTMUSG00000022368 +22720 Zfp62 MGI:MGI:99662|Ensembl:ENSMUSG00000046311|Vega:OTTMUSG00000005549 +22722 Zfp64 MGI:MGI:107342|Ensembl:ENSMUSG00000027551|Vega:OTTMUSG00000016118 +22724 Zbtb7b MGI:MGI:102755|Ensembl:ENSMUSG00000028042|Vega:OTTMUSG00000021268 +22746 Zfp85 MGI:MGI:107767|Ensembl:ENSMUSG00000058331|Vega:OTTMUSG00000032931 +22750 Zfp9 MGI:MGI:99210|Ensembl:ENSMUSG00000072623|Vega:OTTMUSG00000034569 +22751 Zfp90 MGI:MGI:104786|Ensembl:ENSMUSG00000031907|Vega:OTTMUSG00000061947 +22754 Zfp92 MGI:MGI:108094|Ensembl:ENSMUSG00000031374|Vega:OTTMUSG00000017695 +22755 Zfp93 MGI:MGI:107611|Ensembl:ENSMUSG00000055305|Vega:OTTMUSG00000022364 +22756 Zfp94 MGI:MGI:107610|Ensembl:ENSMUSG00000074282|Vega:OTTMUSG00000022367 +22757 Zkscan5 MGI:MGI:107533|Ensembl:ENSMUSG00000055991|Vega:OTTMUSG00000022937 +22758 Zscan12 MGI:MGI:1099444|Ensembl:ENSMUSG00000036721|Vega:OTTMUSG00000000417 +22759 Zfp97 MGI:MGI:105921|Ensembl:ENSMUSG00000095990|Vega:OTTMUSG00000033435 +22761 Zfpm1 MGI:MGI:1095400|Ensembl:ENSMUSG00000049577|Vega:OTTMUSG00000042121 +22762 Zfpm2 MGI:MGI:1334444|Ensembl:ENSMUSG00000022306 +22763 Zfr MGI:MGI:1341890|Ensembl:ENSMUSG00000022201|Vega:OTTMUSG00000033214 +22764 Zfx MGI:MGI:99211|Ensembl:ENSMUSG00000079509|Vega:OTTMUSG00000018032 +22767 Zfy1 MGI:MGI:99212|Ensembl:ENSMUSG00000053211|Vega:OTTMUSG00000045272 +22768 Zfy2 MGI:MGI:99213|Ensembl:ENSMUSG00000000103|Vega:OTTMUSG00000045372 +22770 Zhx1 MGI:MGI:109271|Ensembl:ENSMUSG00000022361|Vega:OTTMUSG00000041982 +22771 Zic1 MGI:MGI:106683|Ensembl:ENSMUSG00000032368|Vega:OTTMUSG00000020412 +22772 Zic2 MGI:MGI:106679|Ensembl:ENSMUSG00000061524|Vega:OTTMUSG00000020302 +22773 Zic3 MGI:MGI:106676|Ensembl:ENSMUSG00000067860|Vega:OTTMUSG00000017528 +22774 Zic4 MGI:MGI:107201|Ensembl:ENSMUSG00000036972|Vega:OTTMUSG00000038052 +22775 Zik1 MGI:MGI:108070|Ensembl:ENSMUSG00000030393|Vega:OTTMUSG00000022345 +22776 Zim1 MGI:MGI:1341879|Ensembl:ENSMUSG00000002266|Vega:OTTMUSG00000027111 +22778 Ikzf1 MGI:MGI:1342540|Ensembl:ENSMUSG00000018654|Vega:OTTMUSG00000005161 +22779 Ikzf2 MGI:MGI:1342541|Ensembl:ENSMUSG00000025997|Vega:OTTMUSG00000047132 +22780 Ikzf3 MGI:MGI:1342542|Ensembl:ENSMUSG00000018168|Vega:OTTMUSG00000006450 +22781 Ikzf4 MGI:MGI:1343139|Ensembl:ENSMUSG00000002578|Vega:OTTMUSG00000025110 +22782 Slc30a1 MGI:MGI:1345281|Ensembl:ENSMUSG00000037434|Vega:OTTMUSG00000021865 +22784 Slc30a3 MGI:MGI:1345280|Ensembl:ENSMUSG00000029151|Vega:OTTMUSG00000015164 +22785 Slc30a4 MGI:MGI:1345282|Ensembl:ENSMUSG00000005802|Vega:OTTMUSG00000015670 +22786 Zp1 MGI:MGI:103073|Ensembl:ENSMUSG00000024734|Vega:OTTMUSG00000036734 +22787 Zp2 MGI:MGI:99214|Ensembl:ENSMUSG00000030911|Vega:OTTMUSG00000059184 +22788 Zp3 MGI:MGI:99215|Ensembl:ENSMUSG00000004948|Vega:OTTMUSG00000025389 +22789 Zp3r MGI:MGI:104965|Ensembl:ENSMUSG00000042554|Vega:OTTMUSG00000026758 +22791 Dnajc2 MGI:MGI:99470|Ensembl:ENSMUSG00000029014|Vega:OTTMUSG00000025676 +22793 Zyx MGI:MGI:103072|Ensembl:ENSMUSG00000029860|Vega:OTTMUSG00000057508 +23789 Coro1b MGI:MGI:1345963|Ensembl:ENSMUSG00000024835|Vega:OTTMUSG00000028310 +23790 Coro1c MGI:MGI:1345964|Ensembl:ENSMUSG00000004530|Vega:OTTMUSG00000036099 +23792 Adam23 MGI:MGI:1345162|Ensembl:ENSMUSG00000025964|Vega:OTTMUSG00000002497 +23793 Adam25 MGI:MGI:1345157|Ensembl:ENSMUSG00000071937|Vega:OTTMUSG00000061121 +23794 Adamts5 MGI:MGI:1346321|Ensembl:ENSMUSG00000022894 +23795 Agr2 MGI:MGI:1344405|Ensembl:ENSMUSG00000020581|Vega:OTTMUSG00000019765 +23796 Aplnr MGI:MGI:1346086|Ensembl:ENSMUSG00000044338|Vega:OTTMUSG00000013465 +23797 Akt3 MGI:MGI:1345147|Ensembl:ENSMUSG00000019699|Vega:OTTMUSG00000020798 +23801 Aloxe3 MGI:MGI:1345140|Ensembl:ENSMUSG00000020892|Vega:OTTMUSG00000005966 +23802 Amfr MGI:MGI:1345634|Ensembl:ENSMUSG00000031751|Vega:OTTMUSG00000027363 +23805 Apc2 MGI:MGI:1346052|Ensembl:ENSMUSG00000020135|Vega:OTTMUSG00000000013 +23806 Arih1 MGI:MGI:1344363|Ensembl:ENSMUSG00000025234|Vega:OTTMUSG00000035819 +23807 Arih2 MGI:MGI:1344361|Ensembl:ENSMUSG00000064145|Vega:OTTMUSG00000050668 +23808 Ash2l MGI:MGI:1344416|Ensembl:ENSMUSG00000031575|Vega:OTTMUSG00000022959 +23809 B160F9S MGI:MGI:1345662 +23810 B160F9T MGI:MGI:1345661 +23811 B292G21S MGI:MGI:1345627 +23812 B292G21T MGI:MGI:1345625 +23813 B430B21S MGI:MGI:1345639 +23814 B430B21T MGI:MGI:1345636 +23815 B437A17S MGI:MGI:1345644 +23816 B437A17T MGI:MGI:1345647 +23817 B446L11S MGI:MGI:1345659 +23818 B446L11T MGI:MGI:1345660 +23819 B489B12S MGI:MGI:1345652 +23820 B489B12T MGI:MGI:1345650 +23821 Bace1 MGI:MGI:1346542|Ensembl:ENSMUSG00000032086|Vega:OTTMUSG00000034962 +23825 Banf1 MGI:MGI:1346330|Ensembl:ENSMUSG00000024844 +23827 Bpnt1 MGI:MGI:1338800|Ensembl:ENSMUSG00000026617|Vega:OTTMUSG00000021435 +23828 Bves MGI:MGI:1346013|Ensembl:ENSMUSG00000071317|Vega:OTTMUSG00000063720 +23829 C1ql1 MGI:MGI:1344400|Ensembl:ENSMUSG00000045532|Vega:OTTMUSG00000003099 +23830 Capn10 MGI:MGI:1344392|Ensembl:ENSMUSG00000026270|Vega:OTTMUSG00000026368 +23831 Car14 MGI:MGI:1344341|Ensembl:ENSMUSG00000038526|Vega:OTTMUSG00000022182 +23832 Xcr1 MGI:MGI:1346338|Ensembl:ENSMUSG00000060509|Vega:OTTMUSG00000043096 +23833 Cd52 MGI:MGI:1346088|Ensembl:ENSMUSG00000000682|Vega:OTTMUSG00000010233 +23834 Cdc6 MGI:MGI:1345150|Ensembl:ENSMUSG00000017499|Vega:OTTMUSG00000006454 +23836 Cdh20 MGI:MGI:1346069|Ensembl:ENSMUSG00000050840|Vega:OTTMUSG00000025409 +23837 Cfdp1 MGI:MGI:1344403|Ensembl:ENSMUSG00000031954|Vega:OTTMUSG00000061803 +23844 Clca1 MGI:MGI:1346342|Ensembl:ENSMUSG00000028255|Vega:OTTMUSG00000055185 +23845 Clec5a MGI:MGI:1345151|Ensembl:ENSMUSG00000029915|Vega:OTTMUSG00000026898 +23849 Klf6 MGI:MGI:1346318|Ensembl:ENSMUSG00000000078 +23850 Pappa2 MGI:MGI:3051647|Ensembl:ENSMUSG00000073530|Vega:OTTMUSG00000029804 +23853 Def6 MGI:MGI:1346328|Ensembl:ENSMUSG00000002257|Vega:OTTMUSG00000023387 +23854 Def8 MGI:MGI:1346331|Ensembl:ENSMUSG00000001482|Vega:OTTMUSG00000022172 +23855 Defa17 MGI:MGI:1345152|Ensembl:ENSMUSG00000060208|Vega:OTTMUSG00000019892 +23856 Dido1 MGI:MGI:1344352|Ensembl:ENSMUSG00000038914|Vega:OTTMUSG00000016359 +23857 Dmtf1 MGI:MGI:1344415|Ensembl:ENSMUSG00000042508|Vega:OTTMUSG00000036456 +23859 Dlg2 MGI:MGI:1344351|Ensembl:ENSMUSG00000052572|Vega:OTTMUSG00000016974 +23863 Dand5 MGI:MGI:1344365|Ensembl:ENSMUSG00000053226 +23871 Ets1 MGI:MGI:95455|Ensembl:ENSMUSG00000032035|Vega:OTTMUSG00000044662 +23872 Ets2 MGI:MGI:95456|Ensembl:ENSMUSG00000022895|Vega:OTTMUSG00000027024 +23873 Faim MGI:MGI:1344387|Ensembl:ENSMUSG00000032463|Vega:OTTMUSG00000048179 +23874 Farsb MGI:MGI:1346035|Ensembl:ENSMUSG00000026245|Vega:OTTMUSG00000047790 +23876 Fbln5 MGI:MGI:1346091|Ensembl:ENSMUSG00000021186 +23877 Fiz1 MGI:MGI:1344336|Ensembl:ENSMUSG00000061374|Vega:OTTMUSG00000059869 +23879 Fxr2 MGI:MGI:1346074|Ensembl:ENSMUSG00000018765|Vega:OTTMUSG00000006005 +23880 Fyb MGI:MGI:1346327|Ensembl:ENSMUSG00000022148|Vega:OTTMUSG00000034885 +23881 G3bp2 MGI:MGI:2442040|Ensembl:ENSMUSG00000029405|Vega:OTTMUSG00000055584 +23882 Gadd45g MGI:MGI:1346325|Ensembl:ENSMUSG00000021453|Vega:OTTMUSG00000023076 +23885 Gmcl1 MGI:MGI:1345156|Ensembl:ENSMUSG00000001157|Vega:OTTMUSG00000024678 +23886 Gdf15 MGI:MGI:1346047|Ensembl:ENSMUSG00000038508|Vega:OTTMUSG00000023705 +23887 Ggt5 MGI:MGI:1346063|Ensembl:ENSMUSG00000006344|Vega:OTTMUSG00000046608 +23888 Gpc6 MGI:MGI:1346322|Ensembl:ENSMUSG00000058571|Vega:OTTMUSG00000018004 +23890 Gpr34 MGI:MGI:1346334|Ensembl:ENSMUSG00000040229|Vega:OTTMUSG00000016906 +23892 Grem1 MGI:MGI:1344337|Ensembl:ENSMUSG00000074934|Vega:OTTMUSG00000014814 +23893 Grem2 MGI:MGI:1344367|Ensembl:ENSMUSG00000050069|Vega:OTTMUSG00000022494 +23894 Gtf2h2 MGI:MGI:1345669|Ensembl:ENSMUSG00000021639|Vega:OTTMUSG00000023202 +23897 Hax1 MGI:MGI:1346319|Ensembl:ENSMUSG00000027944|Vega:OTTMUSG00000052886 +23900 Hcst MGI:MGI:1344360|Ensembl:ENSMUSG00000064109|Vega:OTTMUSG00000059358 +23906 Hnrpfl MGI:MGI:1344419 +23908 Hs2st1 MGI:MGI:1346049|Ensembl:ENSMUSG00000040151|Vega:OTTMUSG00000034172 +23912 Rhof MGI:MGI:1345629|Ensembl:ENSMUSG00000029449|Vega:OTTMUSG00000030767 +23914 Ifld3 MGI:MGI:1345615 +23915 Ifld4 MGI:MGI:1345617 +23916 Ifld5 MGI:MGI:1345618 +23917 Impdh1 MGI:MGI:96567|Ensembl:ENSMUSG00000003500|Vega:OTTMUSG00000033782 +23918 Impdh2 MGI:MGI:109367|Ensembl:ENSMUSG00000062867|Vega:OTTMUSG00000050763 +23919 Insl5 MGI:MGI:1346085|Ensembl:ENSMUSG00000066090|Vega:OTTMUSG00000008072 +23920 Insrr MGI:MGI:1346037|Ensembl:ENSMUSG00000005640|Vega:OTTMUSG00000035156 +23921 Sh2b2 MGI:MGI:1345171|Ensembl:ENSMUSG00000005057|Vega:OTTMUSG00000054381 +23922 Jtb MGI:MGI:1346082|Ensembl:ENSMUSG00000027937|Vega:OTTMUSG00000021952 +23923 Aadat MGI:MGI:1345167|Ensembl:ENSMUSG00000057228|Vega:OTTMUSG00000060946 +23924 Katna1 MGI:MGI:1344353|Ensembl:ENSMUSG00000019794|Vega:OTTMUSG00000035234 +23925 Kel MGI:MGI:1346053|Ensembl:ENSMUSG00000029866|Vega:OTTMUSG00000026360 +23927 Krtap14 MGI:MGI:1346079|Ensembl:ENSMUSG00000074928|Vega:OTTMUSG00000044992 +23928 Lamc3 MGI:MGI:1344394|Ensembl:ENSMUSG00000026840|Vega:OTTMUSG00000012245 +23934 Ly6h MGI:MGI:1346030|Ensembl:ENSMUSG00000022577|Vega:OTTMUSG00000033674 +23936 Lynx1 MGI:MGI:1345180|Ensembl:ENSMUSG00000022594|Vega:OTTMUSG00000045143 +23937 Mab21l2 MGI:MGI:1346022|Ensembl:ENSMUSG00000057777 +23938 Map2k5 MGI:MGI:1346345|Ensembl:ENSMUSG00000058444|Vega:OTTMUSG00000062570 +23939 Mapk7 MGI:MGI:1346347|Ensembl:ENSMUSG00000001034|Vega:OTTMUSG00000005833 +23942 Mta2 MGI:MGI:1346340|Ensembl:ENSMUSG00000071646|Vega:OTTMUSG00000017291 +23943 Esyt1 MGI:MGI:1344426|Ensembl:ENSMUSG00000025366 +23945 Mgll MGI:MGI:1346042|Ensembl:ENSMUSG00000033174|Vega:OTTMUSG00000023902 +23947 Mid2 MGI:MGI:1344333|Ensembl:ENSMUSG00000000266|Vega:OTTMUSG00000018849 +23948 Mmp17 MGI:MGI:1346076|Ensembl:ENSMUSG00000029436|Vega:OTTMUSG00000042407 +23950 Dnajb6 MGI:MGI:1344381|Ensembl:ENSMUSG00000029131|Vega:OTTMUSG00000024721 +23951 mwfh MGI:MGI:1344358 +23954 Nek3 MGI:MGI:1344371|Ensembl:ENSMUSG00000031478|Vega:OTTMUSG00000030469 +23955 Nek4 MGI:MGI:1344404|Ensembl:ENSMUSG00000021918 +23956 Neu2 MGI:MGI:1344417|Ensembl:ENSMUSG00000079434|Vega:OTTMUSG00000036754 +23957 Nr0b2 MGI:MGI:1346344|Ensembl:ENSMUSG00000037583|Vega:OTTMUSG00000011155 +23958 Nr2e3 MGI:MGI:1346317|Ensembl:ENSMUSG00000032292|Vega:OTTMUSG00000023008 +23959 Nt5e MGI:MGI:99782|Ensembl:ENSMUSG00000032420|Vega:OTTMUSG00000045593 +23960 Oas1g MGI:MGI:97429|Ensembl:ENSMUSG00000066861|Vega:OTTMUSG00000030607 +23961 Oas1b MGI:MGI:97430|Ensembl:ENSMUSG00000029605|Vega:OTTMUSG00000043313 +23962 Oasl2 MGI:MGI:1344390|Ensembl:ENSMUSG00000029561|Vega:OTTMUSG00000014606 +23963 Tenm1 MGI:MGI:1345185|Ensembl:ENSMUSG00000016150|Vega:OTTMUSG00000017325 +23964 Tenm2 MGI:MGI:1345184|Ensembl:ENSMUSG00000049336|Vega:OTTMUSG00000005420 +23965 Tenm3 MGI:MGI:1345183|Ensembl:ENSMUSG00000031561|Vega:OTTMUSG00000021119 +23966 Tenm4 MGI:MGI:2447063|Ensembl:ENSMUSG00000048078|Vega:OTTMUSG00000021244 +23967 Osr1 MGI:MGI:1344424|Ensembl:ENSMUSG00000048387 +23968 Nlrp5 MGI:MGI:1345193|Ensembl:ENSMUSG00000015721|Vega:OTTMUSG00000024411 +23969 Pacsin1 MGI:MGI:1345181|Ensembl:ENSMUSG00000040276|Vega:OTTMUSG00000021338 +23970 Pacsin2 MGI:MGI:1345153|Ensembl:ENSMUSG00000016664 +23971 Papss1 MGI:MGI:1330587|Ensembl:ENSMUSG00000028032|Vega:OTTMUSG00000054899 +23972 Papss2 MGI:MGI:1330223|Ensembl:ENSMUSG00000024899 +23980 Pebp1 MGI:MGI:1344408|Ensembl:ENSMUSG00000032959|Vega:OTTMUSG00000025757 +23983 Pcbp1 MGI:MGI:1345635|Ensembl:ENSMUSG00000051695|Vega:OTTMUSG00000022709 +23984 Pde10a MGI:MGI:1345143|Ensembl:ENSMUSG00000023868|Vega:OTTMUSG00000021581 +23985 Slc26a4 MGI:MGI:1346029|Ensembl:ENSMUSG00000020651 +23986 Eci2 MGI:MGI:1346064|Ensembl:ENSMUSG00000021417|Vega:OTTMUSG00000035939 +23988 Pin1 MGI:MGI:1346036|Ensembl:ENSMUSG00000032171|Vega:OTTMUSG00000062734 +23989 Med24 MGI:MGI:1344385|Ensembl:ENSMUSG00000017210|Vega:OTTMUSG00000006403 +23991 Cib1 MGI:MGI:1344418|Ensembl:ENSMUSG00000030538|Vega:OTTMUSG00000022916 +23992 Prkra MGI:MGI:1344375|Ensembl:ENSMUSG00000002731|Vega:OTTMUSG00000013128 +23993 Klk7 MGI:MGI:1346336|Ensembl:ENSMUSG00000030713|Vega:OTTMUSG00000058313 +23994 Dazap2 MGI:MGI:1344344|Ensembl:ENSMUSG00000000346 +23996 Psmc4 MGI:MGI:1346093|Ensembl:ENSMUSG00000030603|Vega:OTTMUSG00000025054 +23997 Psmd13 MGI:MGI:1345192|Ensembl:ENSMUSG00000025487|Vega:OTTMUSG00000023443 +23999 Twf2 MGI:MGI:1346078|Ensembl:ENSMUSG00000023277|Vega:OTTMUSG00000049421 +24000 Ptpn21 MGI:MGI:1344406|Ensembl:ENSMUSG00000021009 +24001 Tiam2 MGI:MGI:1344338|Ensembl:ENSMUSG00000023800 +24004 Rai2 MGI:MGI:1344378|Ensembl:ENSMUSG00000043518|Vega:OTTMUSG00000019477 +24010 Ik MGI:MGI:1345142|Ensembl:ENSMUSG00000024474 +24012 Rgs7 MGI:MGI:1346089|Ensembl:ENSMUSG00000026527|Vega:OTTMUSG00000050245 +24013 Grk1 MGI:MGI:1345146|Ensembl:ENSMUSG00000031450|Vega:OTTMUSG00000060906 +24014 Rnasel MGI:MGI:1098272|Ensembl:ENSMUSG00000066800|Vega:OTTMUSG00000043573 +24015 Abce1 MGI:MGI:1195458|Ensembl:ENSMUSG00000058355|Vega:OTTMUSG00000061313 +24017 Rnf13 MGI:MGI:1346341|Ensembl:ENSMUSG00000036503|Vega:OTTMUSG00000052906 +24018 Rngtt MGI:MGI:1329041|Ensembl:ENSMUSG00000028274|Vega:OTTMUSG00000004938 +24030 Mrps12 MGI:MGI:1346333|Ensembl:ENSMUSG00000045948|Vega:OTTMUSG00000035358 +24044 Scamp2 MGI:MGI:1346518|Ensembl:ENSMUSG00000040188|Vega:OTTMUSG00000063190 +24045 Scamp3 MGI:MGI:1346346|Ensembl:ENSMUSG00000028049|Vega:OTTMUSG00000029730 +24046 Scn11a MGI:MGI:1345149|Ensembl:ENSMUSG00000034115|Vega:OTTMUSG00000062994 +24047 Ccl19 MGI:MGI:1346316|Ensembl:ENSMUSG00000071005|Vega:OTTMUSG00000006591 +24050 Sept3 MGI:MGI:1345148|Ensembl:ENSMUSG00000022456 +24051 Sgcb MGI:MGI:1346523|Ensembl:ENSMUSG00000029156|Vega:OTTMUSG00000055946 +24052 Sgcd MGI:MGI:1346525|Ensembl:ENSMUSG00000020354|Vega:OTTMUSG00000005512 +24053 Sgcg MGI:MGI:1346524|Ensembl:ENSMUSG00000035296|Vega:OTTMUSG00000029985 +24054 sgl MGI:MGI:1345178 +24055 Sh3bp2 MGI:MGI:1346349|Ensembl:ENSMUSG00000054520|Vega:OTTMUSG00000026739 +24056 Sh3bp5 MGI:MGI:1344391|Ensembl:ENSMUSG00000021892|Vega:OTTMUSG00000027880 +24057 Sh3yl1 MGI:MGI:1346118|Ensembl:ENSMUSG00000020669|Vega:OTTMUSG00000027535 +24058 Sigirr MGI:MGI:1344402|Ensembl:ENSMUSG00000025494|Vega:OTTMUSG00000060386 +24059 Slco2a1 MGI:MGI:1346021|Ensembl:ENSMUSG00000032548|Vega:OTTMUSG00000048443 +24060 Slc35a1 MGI:MGI:1345622|Ensembl:ENSMUSG00000028293|Vega:OTTMUSG00000006413 +24061 Smc1a MGI:MGI:1344345|Ensembl:ENSMUSG00000041133|Vega:OTTMUSG00000019685 +24063 Spry1 MGI:MGI:1345139|Ensembl:ENSMUSG00000037211|Vega:OTTMUSG00000007497 +24064 Spry2 MGI:MGI:1345138|Ensembl:ENSMUSG00000022114 +24066 Spry4 MGI:MGI:1345144|Ensembl:ENSMUSG00000024427 +24067 Srp54a MGI:MGI:1346087|Ensembl:ENSMUSG00000073079 +24068 Sra1 MGI:MGI:1344414|Ensembl:ENSMUSG00000006050|Vega:OTTMUSG00000038237 +24069 Sufu MGI:MGI:1345643|Ensembl:ENSMUSG00000025231|Vega:OTTMUSG00000030508 +24070 Mpdu1 MGI:MGI:1346040|Ensembl:ENSMUSG00000018761|Vega:OTTMUSG00000006008 +24071 Synj2bp MGI:MGI:1344347|Ensembl:ENSMUSG00000090935|Vega:OTTMUSG00000035328 +24074 Taf7 MGI:MGI:1346348|Ensembl:ENSMUSG00000051316|Vega:OTTMUSG00000034268 +24075 Taf10 MGI:MGI:1346320|Ensembl:ENSMUSG00000043866|Vega:OTTMUSG00000025599 +24078 Tcra-V22.1 MGI:MGI:1346323 +24079 Tcra-V22.2 MGI:MGI:1346337 +24080 Tcra-V22.3 MGI:MGI:1346324 +24081 Tcra-V22.4 MGI:MGI:1346326 +24082 Map2k3os MGI:MGI:1344334|Ensembl:ENSMUSG00000042549 +24083 Natd1 MGI:MGI:1344388|Ensembl:ENSMUSG00000018931|Vega:OTTMUSG00000005822 +24084 Tekt2 MGI:MGI:1346335|Ensembl:ENSMUSG00000028845|Vega:OTTMUSG00000009354 +24086 Tlk2 MGI:MGI:1346023|Ensembl:ENSMUSG00000020694|Vega:OTTMUSG00000002830 +24087 Tll2 MGI:MGI:1346044|Ensembl:ENSMUSG00000025013 +24088 Tlr2 MGI:MGI:1346060|Ensembl:ENSMUSG00000027995|Vega:OTTMUSG00000051567 +24099 Tnfsf13b MGI:MGI:1344376|Ensembl:ENSMUSG00000031497|Vega:OTTMUSG00000059081 +24100 Tpra1 MGI:MGI:1345190|Ensembl:ENSMUSG00000002871|Vega:OTTMUSG00000024013 +24102 Trex2 MGI:MGI:1346343|Ensembl:ENSMUSG00000031372|Vega:OTTMUSG00000017688 +24105 Rbck1 MGI:MGI:1344372|Ensembl:ENSMUSG00000027466|Vega:OTTMUSG00000015834 +24108 Ubd MGI:MGI:1344410|Ensembl:ENSMUSG00000035186|Vega:OTTMUSG00000037330 +24109 Ubl3 MGI:MGI:1344373|Ensembl:ENSMUSG00000001687|Vega:OTTMUSG00000055806 +24110 Usp18 MGI:MGI:1344364|Ensembl:ENSMUSG00000030107|Vega:OTTMUSG00000056866 +24111 Uts2 MGI:MGI:1346329|Ensembl:ENSMUSG00000028963|Vega:OTTMUSG00000010240 +24112 Vmn1r49 MGI:MGI:1344384|Ensembl:ENSMUSG00000095932|Vega:OTTMUSG00000037450 +24113 Vax2 MGI:MGI:1346018|Ensembl:ENSMUSG00000034777|Vega:OTTMUSG00000037561 +24115 Best1 MGI:MGI:1346332|Ensembl:ENSMUSG00000037418|Vega:OTTMUSG00000028256 +24116 Nelfa MGI:MGI:1346098|Ensembl:ENSMUSG00000029111|Vega:OTTMUSG00000025105 +24117 Wif1 MGI:MGI:1344332|Ensembl:ENSMUSG00000020218|Vega:OTTMUSG00000027724 +24127 Xrn1 MGI:MGI:891964|Ensembl:ENSMUSG00000032410|Vega:OTTMUSG00000047300 +24128 Xrn2 MGI:MGI:894687|Ensembl:ENSMUSG00000027433|Vega:OTTMUSG00000015692 +24129 Y301C7L MGI:MGI:1345630 +24131 Ldb3 MGI:MGI:1344412|Ensembl:ENSMUSG00000021798 +24132 Zfp53 MGI:MGI:99200|Ensembl:ENSMUSG00000057409 +24135 Zfp68 MGI:MGI:1344427|Ensembl:ENSMUSG00000058291|Vega:OTTMUSG00000022803 +24136 Zeb2 MGI:MGI:1344407|Ensembl:ENSMUSG00000026872|Vega:OTTMUSG00000012355 +26356 Ing1 MGI:MGI:1349481|Ensembl:ENSMUSG00000045969|Vega:OTTMUSG00000060767 +26357 Abcg2 MGI:MGI:1347061|Ensembl:ENSMUSG00000029802|Vega:OTTMUSG00000022209 +26358 Aldh1a7 MGI:MGI:1347050|Ensembl:ENSMUSG00000024747|Vega:OTTMUSG00000028314 +26359 Anxa10 MGI:MGI:1347090|Ensembl:ENSMUSG00000031635|Vega:OTTMUSG00000060971 +26360 Angptl2 MGI:MGI:1347002|Ensembl:ENSMUSG00000004105|Vega:OTTMUSG00000012579 +26361 Avpr1b MGI:MGI:1347010|Ensembl:ENSMUSG00000026432|Vega:OTTMUSG00000020888 +26362 Axl MGI:MGI:1347244|Ensembl:ENSMUSG00000002602|Vega:OTTMUSG00000022291 +26363 Btd MGI:MGI:1347001|Ensembl:ENSMUSG00000021900|Vega:OTTMUSG00000024614 +26364 Adgre5 MGI:MGI:1347095|Ensembl:ENSMUSG00000002885|Vega:OTTMUSG00000022225 +26365 Ceacam1 MGI:MGI:1347245|Ensembl:ENSMUSG00000074272|Vega:OTTMUSG00000058252 +26366 Ceacam10 MGI:MGI:1347248|Ensembl:ENSMUSG00000054169|Vega:OTTMUSG00000058236 +26367 Ceacam2 MGI:MGI:1347246|Ensembl:ENSMUSG00000054385|Vega:OTTMUSG00000025351 +26368 Ceacam9 MGI:MGI:1347247|Ensembl:ENSMUSG00000007209|Vega:OTTMUSG00000058017 +26369 Cetn1 MGI:MGI:1347086|Ensembl:ENSMUSG00000050996 +26370 Cetn2 MGI:MGI:1347085|Ensembl:ENSMUSG00000031347|Vega:OTTMUSG00000017845 +26371 Ciao1 MGI:MGI:1346998|Ensembl:ENSMUSG00000003662|Vega:OTTMUSG00000016012 +26372 Clcn6 MGI:MGI:1347049|Ensembl:ENSMUSG00000029016|Vega:OTTMUSG00000010195 +26373 Clcn7 MGI:MGI:1347048|Ensembl:ENSMUSG00000036636|Vega:OTTMUSG00000031166 +26374 Rfwd2 MGI:MGI:1347046|Ensembl:ENSMUSG00000040782|Vega:OTTMUSG00000050285 +26377 Dapp1 MGI:MGI:1347063|Ensembl:ENSMUSG00000028159|Vega:OTTMUSG00000022230 +26378 Decr2 MGI:MGI:1347059|Ensembl:ENSMUSG00000036775|Vega:OTTMUSG00000021323 +26379 Esrra MGI:MGI:1346831|Ensembl:ENSMUSG00000024955|Vega:OTTMUSG00000023201 +26380 Esrrb MGI:MGI:1346832|Ensembl:ENSMUSG00000021255|Vega:OTTMUSG00000023036 +26381 Esrrg MGI:MGI:1347056|Ensembl:ENSMUSG00000026610|Vega:OTTMUSG00000022373 +26382 Fgd2 MGI:MGI:1347084|Ensembl:ENSMUSG00000024013|Vega:OTTMUSG00000028987 +26383 Fto MGI:MGI:1347093|Ensembl:ENSMUSG00000055932|Vega:OTTMUSG00000025730 +26384 Gnpda1 MGI:MGI:1347054|Ensembl:ENSMUSG00000052102|Vega:OTTMUSG00000028078 +26385 Grk6 MGI:MGI:1347078|Ensembl:ENSMUSG00000074886 +26386 Hsf4 MGI:MGI:1347058|Ensembl:ENSMUSG00000033249|Vega:OTTMUSG00000036906 +26388 Ifi202b MGI:MGI:1347083|Ensembl:ENSMUSG00000026535|Vega:OTTMUSG00000050204 +26389 Ifi202c MGI:MGI:1347082 +26390 Mapkbp1 MGI:MGI:1347004|Ensembl:ENSMUSG00000033902|Vega:OTTMUSG00000015276 +26394 Lypla2 MGI:MGI:1347000|Ensembl:ENSMUSG00000028670|Vega:OTTMUSG00000009849 +26395 Map2k1 MGI:MGI:1346866|Ensembl:ENSMUSG00000004936|Vega:OTTMUSG00000016895 +26396 Map2k2 MGI:MGI:1346867|Ensembl:ENSMUSG00000035027|Vega:OTTMUSG00000016975 +26397 Map2k3 MGI:MGI:1346868|Ensembl:ENSMUSG00000018932|Vega:OTTMUSG00000006341 +26398 Map2k4 MGI:MGI:1346869|Ensembl:ENSMUSG00000033352|Vega:OTTMUSG00000005905 +26399 Map2k6 MGI:MGI:1346870|Ensembl:ENSMUSG00000020623|Vega:OTTMUSG00000003325 +26400 Map2k7 MGI:MGI:1346871|Ensembl:ENSMUSG00000002948|Ensembl:ENSMUSG00000109061|Vega:OTTMUSG00000020569|Vega:OTTMUSG00000059344 +26401 Map3k1 MGI:MGI:1346872|Ensembl:ENSMUSG00000021754|Vega:OTTMUSG00000020184 +26403 Map3k11 MGI:MGI:1346880|Ensembl:ENSMUSG00000004054 +26404 Map3k12 MGI:MGI:1346881|Ensembl:ENSMUSG00000023050|Vega:OTTMUSG00000036001 +26405 Map3k2 MGI:MGI:1346873|Ensembl:ENSMUSG00000024383 +26406 Map3k3 MGI:MGI:1346874|Ensembl:ENSMUSG00000020700|Vega:OTTMUSG00000003076 +26407 Map3k4 MGI:MGI:1346875|Ensembl:ENSMUSG00000014426 +26408 Map3k5 MGI:MGI:1346876|Ensembl:ENSMUSG00000071369|Vega:OTTMUSG00000031050 +26409 Map3k7 MGI:MGI:1346877|Ensembl:ENSMUSG00000028284|Vega:OTTMUSG00000004905 +26410 Map3k8 MGI:MGI:1346878|Ensembl:ENSMUSG00000024235|Vega:OTTMUSG00000037645 +26411 Map4k1 MGI:MGI:1346882|Ensembl:ENSMUSG00000037337|Vega:OTTMUSG00000059210 +26412 Map4k2 MGI:MGI:1346883|Ensembl:ENSMUSG00000024948|Vega:OTTMUSG00000018616 +26413 Mapk1 MGI:MGI:1346858|Ensembl:ENSMUSG00000063358|Vega:OTTMUSG00000020203 +26414 Mapk10 MGI:MGI:1346863|Ensembl:ENSMUSG00000046709|Vega:OTTMUSG00000016343 +26415 Mapk13 MGI:MGI:1346864|Ensembl:ENSMUSG00000004864|Vega:OTTMUSG00000024249 +26416 Mapk14 MGI:MGI:1346865|Ensembl:ENSMUSG00000053436|Vega:OTTMUSG00000020086 +26417 Mapk3 MGI:MGI:1346859|Ensembl:ENSMUSG00000063065|Vega:OTTMUSG00000016478 +26419 Mapk8 MGI:MGI:1346861|Ensembl:ENSMUSG00000021936|Vega:OTTMUSG00000018229 +26420 Mapk9 MGI:MGI:1346862|Ensembl:ENSMUSG00000020366|Vega:OTTMUSG00000005569 +26421 Prl2c4 MGI:MGI:1347041 +26422 Nbea MGI:MGI:1347075|Ensembl:ENSMUSG00000027799|Vega:OTTMUSG00000053045 +26423 Nr5a1 MGI:MGI:1346833|Ensembl:ENSMUSG00000026751|Vega:OTTMUSG00000012867 +26424 Nr5a2 MGI:MGI:1346834|Ensembl:ENSMUSG00000026398|Vega:OTTMUSG00000049882 +26425 Nubp1 MGI:MGI:1347073|Ensembl:ENSMUSG00000022503|Vega:OTTMUSG00000025747 +26426 Nubp2 MGI:MGI:1347072|Ensembl:ENSMUSG00000039183 +26427 Creb3l1 MGI:MGI:1347062|Ensembl:ENSMUSG00000027230|Vega:OTTMUSG00000014377 +26428 Orc4 MGI:MGI:1347043|Ensembl:ENSMUSG00000026761|Vega:OTTMUSG00000012397 +26429 Orc5 MGI:MGI:1347044|Ensembl:ENSMUSG00000029012|Vega:OTTMUSG00000021441 +26430 Parg MGI:MGI:1347094|Ensembl:ENSMUSG00000021911|Vega:OTTMUSG00000036550 +26431 Git2 MGI:MGI:1347053|Ensembl:ENSMUSG00000041890|Vega:OTTMUSG00000014548 +26432 Plod2 MGI:MGI:1347007|Ensembl:ENSMUSG00000032374|Vega:OTTMUSG00000031153 +26433 Plod3 MGI:MGI:1347008|Ensembl:ENSMUSG00000004846|Vega:OTTMUSG00000023396 +26434 Prnd MGI:MGI:1346999|Ensembl:ENSMUSG00000027338|Vega:OTTMUSG00000014845 +26436 Psg16 MGI:MGI:1347249|Ensembl:ENSMUSG00000066760|Vega:OTTMUSG00000027139 +26437 Psg17 MGI:MGI:1347250|Ensembl:ENSMUSG00000004540|Vega:OTTMUSG00000017162 +26438 Psg18 MGI:MGI:1347251|Ensembl:ENSMUSG00000003505|Vega:OTTMUSG00000043486 +26439 Psg19 MGI:MGI:1347252|Ensembl:ENSMUSG00000004542|Vega:OTTMUSG00000043487 +26440 Psma1 MGI:MGI:1347005|Ensembl:ENSMUSG00000030751|Vega:OTTMUSG00000025343 +26441 Psma4 MGI:MGI:1347060|Ensembl:ENSMUSG00000032301|Vega:OTTMUSG00000036073 +26442 Psma5 MGI:MGI:1347009|Ensembl:ENSMUSG00000068749|Vega:OTTMUSG00000007299 +26443 Psma6 MGI:MGI:1347006|Ensembl:ENSMUSG00000021024|Vega:OTTMUSG00000034926 +26444 Psma7 MGI:MGI:1347070|Ensembl:ENSMUSG00000027566|Vega:OTTMUSG00000016235 +26445 Psmb2 MGI:MGI:1347045|Ensembl:ENSMUSG00000028837|Vega:OTTMUSG00000009281 +26446 Psmb3 MGI:MGI:1347014|Ensembl:ENSMUSG00000069744|Vega:OTTMUSG00000002743 +26447 Poli MGI:MGI:1347081|Ensembl:ENSMUSG00000038425|Vega:OTTMUSG00000027289 +26448 Mok MGI:MGI:1336881|Ensembl:ENSMUSG00000056458|Vega:OTTMUSG00000042052 +26450 Rbbp9 MGI:MGI:1347074|Ensembl:ENSMUSG00000027428|Vega:OTTMUSG00000003921 +26451 Rpl27a MGI:MGI:1347076|Ensembl:ENSMUSG00000046364|Vega:OTTMUSG00000022787 +26456 Sema4g MGI:MGI:1347047|Ensembl:ENSMUSG00000025207|Vega:OTTMUSG00000014898 +26457 Slc27a1 MGI:MGI:1347098|Ensembl:ENSMUSG00000031808|Vega:OTTMUSG00000062164 +26458 Slc27a2 MGI:MGI:1347099|Ensembl:ENSMUSG00000027359|Vega:OTTMUSG00000015755 +26459 Slc27a5 MGI:MGI:1347100|Ensembl:ENSMUSG00000030382|Vega:OTTMUSG00000027130 +26462 Txnrd2 MGI:MGI:1347023|Ensembl:ENSMUSG00000075704|Vega:OTTMUSG00000026082 +26463 Ube2l3-ps1 MGI:MGI:1347022 +26464 Vnn3 MGI:MGI:1347055|Ensembl:ENSMUSG00000020010|Vega:OTTMUSG00000020916 +26465 Zfp146 MGI:MGI:1347092|Ensembl:ENSMUSG00000037029|Vega:OTTMUSG00000022420 +26466 Zfp260 MGI:MGI:1347071|Ensembl:ENSMUSG00000049421|Vega:OTTMUSG00000022415 +26549 Itgb1bp2 MGI:MGI:1353420|Ensembl:ENSMUSG00000031312|Vega:OTTMUSG00000018208 +26554 Cul3 MGI:MGI:1347360|Ensembl:ENSMUSG00000004364|Vega:OTTMUSG00000035349 +26556 Homer1 MGI:MGI:1347345|Ensembl:ENSMUSG00000007617|Vega:OTTMUSG00000016339 +26557 Homer2 MGI:MGI:1347354|Ensembl:ENSMUSG00000025813|Vega:OTTMUSG00000059182 +26558 Homer3 MGI:MGI:1347359|Ensembl:ENSMUSG00000003573|Vega:OTTMUSG00000022250 +26559 Hunk MGI:MGI:1347352|Ensembl:ENSMUSG00000053414 +26560 Krtap15 MGI:MGI:1347350|Ensembl:ENSMUSG00000022931|Vega:OTTMUSG00000044993 +26561 Mmp23 MGI:MGI:1347361|Ensembl:ENSMUSG00000029061|Vega:OTTMUSG00000010727 +26562 Ncdn MGI:MGI:1347351|Ensembl:ENSMUSG00000028833|Vega:OTTMUSG00000009274 +26563 Ror1 MGI:MGI:1347520|Ensembl:ENSMUSG00000035305|Vega:OTTMUSG00000008027 +26564 Ror2 MGI:MGI:1347521|Ensembl:ENSMUSG00000021464|Vega:OTTMUSG00000031749 +26565 Pla2g10 MGI:MGI:1347522|Ensembl:ENSMUSG00000022683|Vega:OTTMUSG00000026305 +26568 Slc27a3 MGI:MGI:1347358|Ensembl:ENSMUSG00000027932|Vega:OTTMUSG00000029600 +26569 Slc27a4 MGI:MGI:1347347|Ensembl:ENSMUSG00000059316|Vega:OTTMUSG00000012688 +26570 Slc7a11 MGI:MGI:1347355|Ensembl:ENSMUSG00000027737|Vega:OTTMUSG00000021262 +26572 Cops3 MGI:MGI:1349409|Ensembl:ENSMUSG00000019373|Vega:OTTMUSG00000008091 +26611 Rcn2 MGI:MGI:1349765|Ensembl:ENSMUSG00000032320|Vega:OTTMUSG00000027450 +26754 Cops5 MGI:MGI:1349415|Ensembl:ENSMUSG00000025917|Vega:OTTMUSG00000029459 +26757 Dpysl4 MGI:MGI:1349764|Ensembl:ENSMUSG00000025478|Vega:OTTMUSG00000027347 +26874 Abcd2 MGI:MGI:1349467|Ensembl:ENSMUSG00000055782 +26875 Pclo MGI:MGI:1349390|Ensembl:ENSMUSG00000061601|Vega:OTTMUSG00000043360 +26876 Adh4 MGI:MGI:1349472|Ensembl:ENSMUSG00000037797|Vega:OTTMUSG00000030507 +26877 B3galt1 MGI:MGI:1349403|Ensembl:ENSMUSG00000034780|Vega:OTTMUSG00000012924 +26878 B3galt2 MGI:MGI:1349461|Ensembl:ENSMUSG00000033849|Vega:OTTMUSG00000030947 +26879 B3galnt1 MGI:MGI:1349405|Ensembl:ENSMUSG00000043300|Vega:OTTMUSG00000051643 +26885 Casp8ap2 MGI:MGI:1349399|Ensembl:ENSMUSG00000028282|Vega:OTTMUSG00000004933 +26886 Cenph MGI:MGI:1349448|Ensembl:ENSMUSG00000045273|Vega:OTTMUSG00000033835 +26887 Chst4 MGI:MGI:1349479|Ensembl:ENSMUSG00000035930|Vega:OTTMUSG00000061887 +26888 Clec4a2 MGI:MGI:1349412|Ensembl:ENSMUSG00000030148|Vega:OTTMUSG00000034576 +26889 Cln8 MGI:MGI:1349447|Ensembl:ENSMUSG00000026317|Vega:OTTMUSG00000032854 +26891 Cops4 MGI:MGI:1349414|Ensembl:ENSMUSG00000035297|Vega:OTTMUSG00000026140 +26893 Cops6 MGI:MGI:1349439|Ensembl:ENSMUSG00000019494|Vega:OTTMUSG00000022638 +26894 Cops7a MGI:MGI:1349400|Ensembl:ENSMUSG00000030127|Vega:OTTMUSG00000023393 +26895 Cops7b MGI:MGI:1349388|Ensembl:ENSMUSG00000026240|Vega:OTTMUSG00000027307 +26896 Med14 MGI:MGI:1349442|Ensembl:ENSMUSG00000064127|Vega:OTTMUSG00000016997 +26897 Acot1 MGI:MGI:1349396|Ensembl:ENSMUSG00000072949 +26898 Ctsj MGI:MGI:1349426|Ensembl:ENSMUSG00000055298 +26900 Ddx3y MGI:MGI:1349406|Ensembl:ENSMUSG00000069045|Vega:OTTMUSG00000045279 +26901 Ss18l2 MGI:MGI:1349474|Ensembl:ENSMUSG00000032526|Vega:OTTMUSG00000062655 +26903 Dysf MGI:MGI:1349385|Ensembl:ENSMUSG00000033788|Vega:OTTMUSG00000022272 +26904 Sh2d1b1 MGI:MGI:1349420|Ensembl:ENSMUSG00000102418|Vega:OTTMUSG00000049940 +26905 Eif2s3x MGI:MGI:1349431|Ensembl:ENSMUSG00000035150|Vega:OTTMUSG00000018084 +26906 Eif2s3x-ps1 MGI:MGI:1349404 +26908 Eif2s3y MGI:MGI:1349430|Ensembl:ENSMUSG00000069049|Vega:OTTMUSG00000021559 +26909 Exo1 MGI:MGI:1349427|Ensembl:ENSMUSG00000039748|Vega:OTTMUSG00000050253 +26910 Figla MGI:MGI:1349421|Ensembl:ENSMUSG00000030001|Vega:OTTMUSG00000056193 +26912 Gcat MGI:MGI:1349389|Ensembl:ENSMUSG00000006378 +26913 Gprin1 MGI:MGI:1349455|Ensembl:ENSMUSG00000069227|Vega:OTTMUSG00000032670 +26914 H2afy MGI:MGI:1349392|Ensembl:ENSMUSG00000015937|Vega:OTTMUSG00000020957 +26918 Ern2 MGI:MGI:1349436|Ensembl:ENSMUSG00000030866|Vega:OTTMUSG00000058105 +26919 Zfp346 MGI:MGI:1349417|Ensembl:ENSMUSG00000021481|Vega:OTTMUSG00000035039 +26920 Cntrl MGI:MGI:1889576|Ensembl:ENSMUSG00000057110|Vega:OTTMUSG00000012039 +26921 Map4k4 MGI:MGI:1349394|Ensembl:ENSMUSG00000026074|Vega:OTTMUSG00000050440 +26922 Mecr MGI:MGI:1349441|Ensembl:ENSMUSG00000028910|Vega:OTTMUSG00000009566 +26926 Aifm1 MGI:MGI:1349419|Ensembl:ENSMUSG00000036932|Vega:OTTMUSG00000017542 +26927 Foxl2 MGI:MGI:1349428|Ensembl:ENSMUSG00000050397|Vega:OTTMUSG00000048289 +26930 Ppnr MGI:MGI:1349458 +26931 Ppp2r5c MGI:MGI:1349475|Ensembl:ENSMUSG00000017843 +26932 Ppp2r5e MGI:MGI:1349473|Ensembl:ENSMUSG00000021051 +26934 Racgap1 MGI:MGI:1349423|Ensembl:ENSMUSG00000023015|Vega:OTTMUSG00000035793 +26936 Mprip MGI:MGI:1349438|Ensembl:ENSMUSG00000005417|Vega:OTTMUSG00000005803 +26938 St6galnac5 MGI:MGI:1349471|Ensembl:ENSMUSG00000039037|Vega:OTTMUSG00000030537 +26939 Polr3e MGI:MGI:1349452|Ensembl:ENSMUSG00000030880|Vega:OTTMUSG00000059323 +26940 Ecsit MGI:MGI:1349469|Ensembl:ENSMUSG00000066839|Vega:OTTMUSG00000042363 +26941 Slc9a3r1 MGI:MGI:1349482|Ensembl:ENSMUSG00000020733|Vega:OTTMUSG00000003641 +26942 Spag1 MGI:MGI:1349387|Ensembl:ENSMUSG00000037617 +26943 Serinc3 MGI:MGI:1349457|Ensembl:ENSMUSG00000017707|Vega:OTTMUSG00000016123 +26944 Tinag MGI:MGI:1349477|Ensembl:ENSMUSG00000032357|Vega:OTTMUSG00000044835 +26945 Tpsg1 MGI:MGI:1349391|Ensembl:ENSMUSG00000033200|Vega:OTTMUSG00000034504 +26946 Trpc7 MGI:MGI:1349470|Ensembl:ENSMUSG00000021541|Vega:OTTMUSG00000024552 +26949 Vat1 MGI:MGI:1349450|Ensembl:ENSMUSG00000034993|Vega:OTTMUSG00000002873 +26950 Vsnl1 MGI:MGI:1349453|Ensembl:ENSMUSG00000054459 +26951 Zw10 MGI:MGI:1349478|Ensembl:ENSMUSG00000032264|Vega:OTTMUSG00000063014 +26961 Rpl8 MGI:MGI:1350927|Ensembl:ENSMUSG00000003970 +26965 Cul1 MGI:MGI:1349658|Ensembl:ENSMUSG00000029686|Vega:OTTMUSG00000022333 +26968 Islr MGI:MGI:1349645|Ensembl:ENSMUSG00000037206|Vega:OTTMUSG00000063233 +26970 Pla2g2e MGI:MGI:1349660|Ensembl:ENSMUSG00000028751|Vega:OTTMUSG00000010067 +26971 Pla2g2f MGI:MGI:1349661|Ensembl:ENSMUSG00000028749|Vega:OTTMUSG00000010006 +26972 Spo11 MGI:MGI:1349669|Ensembl:ENSMUSG00000005883|Vega:OTTMUSG00000016682 +26987 Eif4e2 MGI:MGI:1914440|Ensembl:ENSMUSG00000026254|Vega:OTTMUSG00000021766 +26992 Brd7 MGI:MGI:1349766|Ensembl:ENSMUSG00000031660|Vega:OTTMUSG00000017292 +27007 Klrk1 MGI:MGI:1196250|Ensembl:ENSMUSG00000030149|Vega:OTTMUSG00000032505 +27008 Micall1 MGI:MGI:105870|Ensembl:ENSMUSG00000033039 +27009 D17Mit232.1 MGI:MGI:102414 +27015 Polk MGI:MGI:1349767|Ensembl:ENSMUSG00000021668 +27027 Tspan32 MGI:MGI:1350360|Ensembl:ENSMUSG00000000244|Vega:OTTMUSG00000018786 +27028 Ermap MGI:MGI:1349816|Ensembl:ENSMUSG00000028644|Vega:OTTMUSG00000008860 +27029 Sgsh MGI:MGI:1350341|Ensembl:ENSMUSG00000005043|Vega:OTTMUSG00000003911 +27041 G3bp1 MGI:MGI:1351465|Ensembl:ENSMUSG00000018583|Vega:OTTMUSG00000005694 +27045 Nit1 MGI:MGI:1350916|Ensembl:ENSMUSG00000013997|Vega:OTTMUSG00000021715 +27047 Omd MGI:MGI:1350918|Ensembl:ENSMUSG00000048368 +27049 Etv3 MGI:MGI:1350926|Ensembl:ENSMUSG00000003382|Vega:OTTMUSG00000026642 +27050 Rps3 MGI:MGI:1350917|Ensembl:ENSMUSG00000030744|Vega:OTTMUSG00000025334 +27052 Aoah MGI:MGI:1350928|Ensembl:ENSMUSG00000021322 +27053 Asns MGI:MGI:1350929|Ensembl:ENSMUSG00000029752|Vega:OTTMUSG00000022779 +27054 Sec23b MGI:MGI:1350925|Ensembl:ENSMUSG00000027429|Vega:OTTMUSG00000003918 +27055 Fkbp9 MGI:MGI:1350921|Ensembl:ENSMUSG00000029781|Vega:OTTMUSG00000022504 +27056 Irf5 MGI:MGI:1350924|Ensembl:ENSMUSG00000029771|Vega:OTTMUSG00000035855 +27057 Ncoa4 MGI:MGI:1350932|Ensembl:ENSMUSG00000056234|Vega:OTTMUSG00000036491 +27058 Srp9 MGI:MGI:1350930|Ensembl:ENSMUSG00000026511|Vega:OTTMUSG00000022125 +27059 Sh3d19 MGI:MGI:1350923|Ensembl:ENSMUSG00000028082|Vega:OTTMUSG00000044337 +27060 Tcirg1 MGI:MGI:1350931|Ensembl:ENSMUSG00000001750|Vega:OTTMUSG00000033070 +27061 Bcap31 MGI:MGI:1350933|Ensembl:ENSMUSG00000002015|Vega:OTTMUSG00000017693 +27062 Cadps MGI:MGI:1350922|Ensembl:ENSMUSG00000054423 +27078 B9d1 MGI:MGI:1351471|Ensembl:ENSMUSG00000001039|Vega:OTTMUSG00000005834 +27081 Zfp275 MGI:MGI:1350985|Ensembl:ENSMUSG00000031365|Vega:OTTMUSG00000017691 +27083 Xlr4b MGI:MGI:1350975|Ensembl:ENSMUSG00000067768|Vega:OTTMUSG00000017690 +27084 Xlr5c MGI:MGI:1350981|Ensembl:ENSMUSG00000067764|Vega:OTTMUSG00000017667 +27096 Trappc3 MGI:MGI:1351486|Ensembl:ENSMUSG00000028847|Vega:OTTMUSG00000009355 +27103 Eif2ak4 MGI:MGI:1353427|Ensembl:ENSMUSG00000005102|Vega:OTTMUSG00000015229 +27140 Tlx3 MGI:MGI:1351209|Ensembl:ENSMUSG00000040610|Vega:OTTMUSG00000005392 +27176 Rpl7a MGI:MGI:1353472|Ensembl:ENSMUSG00000062647|Vega:OTTMUSG00000011740 +27204 Syn3 MGI:MGI:1351334|Ensembl:ENSMUSG00000059602|Vega:OTTMUSG00000028681 +27205 Podxl MGI:MGI:1351317|Ensembl:ENSMUSG00000025608|Vega:OTTMUSG00000014732 +27206 Nrk MGI:MGI:1351326|Ensembl:ENSMUSG00000052854|Vega:OTTMUSG00000018696 +27207 Rps11 MGI:MGI:1351329|Ensembl:ENSMUSG00000003429|Vega:OTTMUSG00000058711 +27208 Snord33 MGI:MGI:1351323|Ensembl:ENSMUSG00000065628 +27209 Snord32a MGI:MGI:1351324|Ensembl:ENSMUSG00000065219 +27210 Snord34 MGI:MGI:1351325|Ensembl:ENSMUSG00000065878 +27211 Snord35a MGI:MGI:1351319|Ensembl:ENSMUSG00000065818 +27212 Snord35b MGI:MGI:1351321|Ensembl:ENSMUSG00000064767 +27214 Dbf4 MGI:MGI:1351328|Ensembl:ENSMUSG00000002297|Vega:OTTMUSG00000035269 +27215 Azi2 MGI:MGI:1351332|Ensembl:ENSMUSG00000039285|Vega:OTTMUSG00000034116 +27216 Olfr154 MGI:MGI:1351316|Ensembl:ENSMUSG00000075212|Vega:OTTMUSG00000013519 +27217 Mixl1 MGI:MGI:1351322|Ensembl:ENSMUSG00000026497|Vega:OTTMUSG00000037622 +27218 Slamf1 MGI:MGI:1351314|Ensembl:ENSMUSG00000015316|Vega:OTTMUSG00000035822 +27219 Sgk2 MGI:MGI:1351318|Ensembl:ENSMUSG00000017868|Vega:OTTMUSG00000001152 +27220 Cartpt MGI:MGI:1351330|Ensembl:ENSMUSG00000021647 +27221 Chaf1a MGI:MGI:1351331|Ensembl:ENSMUSG00000002835 +27222 Atp1a4 MGI:MGI:1351335|Ensembl:ENSMUSG00000007107|Vega:OTTMUSG00000021836 +27223 Trp53bp1 MGI:MGI:1351320|Ensembl:ENSMUSG00000043909|Vega:OTTMUSG00000015973 +27224 Eloa MGI:MGI:1351315|Ensembl:ENSMUSG00000028668|Vega:OTTMUSG00000009853 +27225 Ddx24 MGI:MGI:1351337|Ensembl:ENSMUSG00000041645 +27226 Pla2g7 MGI:MGI:1351327|Ensembl:ENSMUSG00000023913|Vega:OTTMUSG00000026307 +27260 Plek2 MGI:MGI:1351466|Ensembl:ENSMUSG00000021118|Vega:OTTMUSG00000027588 +27261 Dok3 MGI:MGI:1351490|Ensembl:ENSMUSG00000035711 +27262 Smok1 MGI:MGI:1351488 +27263 Smok2a MGI:MGI:1351487|Ensembl:ENSMUSG00000073458|Vega:OTTMUSG00000029530 +27267 Cars MGI:MGI:1351477|Ensembl:ENSMUSG00000010755|Vega:OTTMUSG00000024014 +27273 Pdk4 MGI:MGI:1351481|Ensembl:ENSMUSG00000019577|Vega:OTTMUSG00000026853 +27274 Zfp354b MGI:MGI:1351476|Ensembl:ENSMUSG00000020335|Vega:OTTMUSG00000007895 +27275 Nufip1 MGI:MGI:1351474|Ensembl:ENSMUSG00000022009 +27276 Plekhb1 MGI:MGI:1351469|Ensembl:ENSMUSG00000030701|Vega:OTTMUSG00000025179 +27277 Golga5 MGI:MGI:1351475|Ensembl:ENSMUSG00000021192 +27278 Clnk MGI:MGI:1351468|Ensembl:ENSMUSG00000039315|Vega:OTTMUSG00000056284 +27279 Tnfrsf12a MGI:MGI:1351484|Ensembl:ENSMUSG00000023905 +27280 Phlda3 MGI:MGI:1351485|Ensembl:ENSMUSG00000041801|Vega:OTTMUSG00000022104 +27281 Hrasls MGI:MGI:1351473|Ensembl:ENSMUSG00000022525|Vega:OTTMUSG00000028465 +27282 Erv4 MGI:MGI:1351467 +27354 Nbn MGI:MGI:1351625|Ensembl:ENSMUSG00000028224|Vega:OTTMUSG00000004636 +27355 Pald1 MGI:MGI:1351623|Ensembl:ENSMUSG00000020092 +27356 Insl6 MGI:MGI:1351595|Ensembl:ENSMUSG00000050957|Vega:OTTMUSG00000044338 +27357 Gyg MGI:MGI:1351614|Ensembl:ENSMUSG00000019528|Vega:OTTMUSG00000029310 +27358 Defb3 MGI:MGI:1351612|Ensembl:ENSMUSG00000039775|Vega:OTTMUSG00000020668 +27359 Sytl4 MGI:MGI:1351606|Ensembl:ENSMUSG00000031255|Vega:OTTMUSG00000018713 +27360 Add3 MGI:MGI:1351615|Ensembl:ENSMUSG00000025026 +27361 Msrb1 MGI:MGI:1351642|Ensembl:ENSMUSG00000075705|Vega:OTTMUSG00000021061 +27362 Dnajb9 MGI:MGI:1351618|Ensembl:ENSMUSG00000014905 +27364 Srr MGI:MGI:1351636|Ensembl:ENSMUSG00000001323|Vega:OTTMUSG00000006189 +27366 Txnl4a MGI:MGI:1351613|Ensembl:ENSMUSG00000057130|Vega:OTTMUSG00000033180 +27367 Rpl3 MGI:MGI:1351605|Ensembl:ENSMUSG00000060036|Vega:OTTMUSG00000049399 +27368 Tbl2 MGI:MGI:1351652|Ensembl:ENSMUSG00000005374|Vega:OTTMUSG00000026019 +27369 Dguok MGI:MGI:1351602|Ensembl:ENSMUSG00000014554|Vega:OTTMUSG00000022810 +27370 Rps26 MGI:MGI:1351628|Ensembl:ENSMUSG00000025362 +27371 Sh2d2a MGI:MGI:1351596|Ensembl:ENSMUSG00000028071|Vega:OTTMUSG00000051868 +27372 Prl3c1 MGI:MGI:1351649|Ensembl:ENSMUSG00000017922|Vega:OTTMUSG00000000629 +27373 Csnk1e MGI:MGI:1351660|Ensembl:ENSMUSG00000022433|Vega:OTTMUSG00000029589 +27374 Prmt5 MGI:MGI:1351645|Ensembl:ENSMUSG00000023110|Vega:OTTMUSG00000020079 +27375 Tjp3 MGI:MGI:1351650|Ensembl:ENSMUSG00000034917 +27376 Slc25a10 MGI:MGI:1353497|Ensembl:ENSMUSG00000025792|Vega:OTTMUSG00000004270 +27377 Yme1l1 MGI:MGI:1351651|Ensembl:ENSMUSG00000026775|Vega:OTTMUSG00000011633 +27378 Tcl1b3 MGI:MGI:1351600|Ensembl:ENSMUSG00000068940 +27379 Tcl1b1 MGI:MGI:1351601|Ensembl:ENSMUSG00000066359 +27380 Tcl1b4 MGI:MGI:1351604|Ensembl:ENSMUSG00000079007 +27381 Tcl1b2 MGI:MGI:1351609|Ensembl:ENSMUSG00000060863|Vega:OTTMUSG00000033067 +27382 Tcl1b5 MGI:MGI:1351635|Ensembl:ENSMUSG00000000701 +27384 Akr1c13 MGI:MGI:1351662|Ensembl:ENSMUSG00000021213|Vega:OTTMUSG00000027949 +27385 Magel2 MGI:MGI:1351648|Ensembl:ENSMUSG00000056972|Vega:OTTMUSG00000059565 +27386 Npas3 MGI:MGI:1351610|Ensembl:ENSMUSG00000021010 +27387 Sh2d3c MGI:MGI:1351631|Ensembl:ENSMUSG00000059013|Vega:OTTMUSG00000012530 +27388 Ptdss2 MGI:MGI:1351664|Ensembl:ENSMUSG00000025495|Vega:OTTMUSG00000037303 +27389 Dusp13 MGI:MGI:1351599|Ensembl:ENSMUSG00000021768|Vega:OTTMUSG00000027823 +27390 Mmel1 MGI:MGI:1351603|Ensembl:ENSMUSG00000058183|Vega:OTTMUSG00000010458 +27391 L1Md-Tf2 MGI:MGI:1351666 +27392 Pign MGI:MGI:1351629|Ensembl:ENSMUSG00000056536|Vega:OTTMUSG00000048961 +27393 Mrpl39 MGI:MGI:1351620|Ensembl:ENSMUSG00000022889|Vega:OTTMUSG00000023651 +27394 L1Md-Tf16 MGI:MGI:1351632 +27395 Mrpl15 MGI:MGI:1351639|Ensembl:ENSMUSG00000033845|Vega:OTTMUSG00000029329 +27396 L1Md-Tf19 MGI:MGI:1351647 +27397 Mrpl17 MGI:MGI:1351608|Ensembl:ENSMUSG00000030879|Vega:OTTMUSG00000025496 +27398 Mrpl2 MGI:MGI:1351622|Ensembl:ENSMUSG00000002767|Vega:OTTMUSG00000024284 +27399 Ip6k1 MGI:MGI:1351633|Ensembl:ENSMUSG00000032594|Vega:OTTMUSG00000042012 +27400 Hsd17b6 MGI:MGI:1351670|Ensembl:ENSMUSG00000025396 +27401 Skp2 MGI:MGI:1351663|Ensembl:ENSMUSG00000054115|Vega:OTTMUSG00000045656 +27402 Pdhx MGI:MGI:1351627|Ensembl:ENSMUSG00000010914|Vega:OTTMUSG00000014841 +27403 Abca7 MGI:MGI:1351646|Ensembl:ENSMUSG00000035722|Vega:OTTMUSG00000032606 +27404 Abca8b MGI:MGI:1351668|Ensembl:ENSMUSG00000020620|Vega:OTTMUSG00000003354 +27405 Abcg3 MGI:MGI:1351624|Ensembl:ENSMUSG00000029299|Vega:OTTMUSG00000025595 +27406 Abcf3 MGI:MGI:1351656|Ensembl:ENSMUSG00000003234|Vega:OTTMUSG00000023912 +27407 Abcf2 MGI:MGI:1351657|Ensembl:ENSMUSG00000028953|Vega:OTTMUSG00000053669 +27409 Abcg5 MGI:MGI:1351659|Ensembl:ENSMUSG00000040505|Vega:OTTMUSG00000036704 +27410 Abca3 MGI:MGI:1351617|Ensembl:ENSMUSG00000024130|Vega:OTTMUSG00000031259 +27411 Slc14a2 MGI:MGI:1351653|Ensembl:ENSMUSG00000024552 +27412 Peg12 MGI:MGI:1351637|Ensembl:ENSMUSG00000070526|Vega:OTTMUSG00000059567 +27413 Abcb11 MGI:MGI:1351619|Ensembl:ENSMUSG00000027048|Vega:OTTMUSG00000012983 +27414 Sergef MGI:MGI:1351630|Ensembl:ENSMUSG00000030839|Vega:OTTMUSG00000025417 +27416 Abcc5 MGI:MGI:1351644|Ensembl:ENSMUSG00000022822|Vega:OTTMUSG00000025954 +27418 Mkln1 MGI:MGI:1351638|Ensembl:ENSMUSG00000025609|Vega:OTTMUSG00000014731 +27419 Naglu MGI:MGI:1351641|Ensembl:ENSMUSG00000001751|Vega:OTTMUSG00000002689 +27421 Abcc6 MGI:MGI:1351634|Ensembl:ENSMUSG00000030834|Vega:OTTMUSG00000031288 +27423 Klra15 MGI:MGI:1351665 +27424 Klra16 MGI:MGI:1351669 +27425 Atp5l MGI:MGI:1351597|Ensembl:ENSMUSG00000038717|Vega:OTTMUSG00000063377 +27426 Nagpa MGI:MGI:1351598|Ensembl:ENSMUSG00000023143|Vega:OTTMUSG00000028133 +27428 Shroom3 MGI:MGI:1351655|Ensembl:ENSMUSG00000029381|Vega:OTTMUSG00000036945 +27448 1T MGI:MGI:1337001 +27449 8T MGI:MGI:1337036 +27450 1S MGI:MGI:1337127 +27451 10S MGI:MGI:1336996 +27452 53S MGI:MGI:1337012 +27453 15S MGI:MGI:1337020 +27454 53T MGI:MGI:1337021 +27455 38T MGI:MGI:1337038 +27456 44S MGI:MGI:1337064 +27457 15T MGI:MGI:1337091 +27458 E2R MGI:MGI:1337095 +27459 56S MGI:MGI:1337109 +27460 10T MGI:MGI:1337121 +27461 63G5L MGI:MGI:1337019 +27462 17F4L MGI:MGI:1337068 +27463 3S MGI:MGI:1337079 +27464 3T MGI:MGI:1337085 +27465 8S MGI:MGI:1337108 +27466 42T MGI:MGI:1337081 +27467 78A11L MGI:MGI:1336989 +27468 45S MGI:MGI:1337000 +27469 16T MGI:MGI:1337013 +27470 29T MGI:MGI:1337014 +27471 16S MGI:MGI:1337017 +27472 51S MGI:MGI:1337028 +27473 48T MGI:MGI:1337030 +27474 51T MGI:MGI:1337031 +27475 20S MGI:MGI:1337042 +27476 20T MGI:MGI:1337043 +27477 11T MGI:MGI:1337057 +27478 42S MGI:MGI:1337059 +27479 11S MGI:MGI:1337061 +27480 91G12L MGI:MGI:1337093 +27481 78A11R MGI:MGI:1337094 +27482 52T MGI:MGI:1337098 +27483 52S MGI:MGI:1337102 +27484 56T MGI:MGI:1337110 +27485 29S MGI:MGI:1337119 +27486 12T MGI:MGI:1337123 +27489 D0Kist6 MGI:MGI:108435 +27490 D0Kist5 MGI:MGI:108436 +27491 D0Kist4 MGI:MGI:108437 +27492 D0Kist3 MGI:MGI:108438 +27493 A230006K03Rik MGI:MGI:3644205 +27494 Amot MGI:MGI:108440|Ensembl:ENSMUSG00000041688|Vega:OTTMUSG00000018901 +27495 17F4R MGI:MGI:1336990 +27497 3P18T MGI:MGI:1337105 +27498 3P18S MGI:MGI:1337106 +27499 B40B5S MGI:MGI:1346008 +27500 B40B5T MGI:MGI:1346010 +27501 B9L14S MGI:MGI:1346070 +27502 B9L14T MGI:MGI:1346071 +27503 222B5S MGI:MGI:1337033 +27504 222B5T MGI:MGI:1337035 +27505 573K1S MGI:MGI:1337047 +27506 573K1T MGI:MGI:1337053 +27507 Y157F2R MGI:MGI:1346007 +27508 B545C9T MGI:MGI:1346009 +27509 B396H6T MGI:MGI:1346015 +27510 B546P1T MGI:MGI:1346019 +27511 B546P1S MGI:MGI:1346020 +27512 B11I10S MGI:MGI:1346027 +27513 B11I10T MGI:MGI:1346028 +27514 B405C9T MGI:MGI:1346039 +27515 B405C9S MGI:MGI:1346041 +27516 B479N4S MGI:MGI:1346043 +27517 B479N4T MGI:MGI:1346046 +27518 B545C9S MGI:MGI:1346050 +27519 B308D2T MGI:MGI:1346077 +27520 B396H6S MGI:MGI:1346080 +27521 272I21T MGI:MGI:1336999 +27522 268M14S MGI:MGI:1337029 +27523 B520L19T MGI:MGI:1346011 +27524 B520L19S MGI:MGI:1346033 +27525 B432H10S MGI:MGI:1346045 +27526 B432H10T MGI:MGI:1346061 +27527 B521M19S MGI:MGI:1346094 +27528 Nrep MGI:MGI:99444|Ensembl:ENSMUSG00000042834 +27529 D0Mnp3 MGI:MGI:1276099 +27530 D0Mnp2 MGI:MGI:1276100 +27531 D0Mnp1 MGI:MGI:1276101 +27532 D0Mnp6 MGI:MGI:1276103 +27533 D0Mnp5 MGI:MGI:1276104 +27534 D0Mnp4 MGI:MGI:1276105 +27535 D15N9 MGI:MGI:1349459 +27537 D15N3 MGI:MGI:1276514 +27539 D15N8 MGI:MGI:1349460 +27540 D15N5 MGI:MGI:1349463 +27541 D15N4 MGI:MGI:1349464 +27542 D15N7 MGI:MGI:1349465 +27543 D15N6 MGI:MGI:1349466 +27544 D15N11 MGI:MGI:1349424 +27545 D15N10 MGI:MGI:1349425 +27546 D7Zem4 MGI:MGI:1196611 +27547 D7Zem1 MGI:MGI:1196613 +27548 D7Zem3 MGI:MGI:1196614 +27549 D7Zem2 MGI:MGI:1196626 +27550 D5Buc9 MGI:MGI:1343467 +27551 D5Buc8 MGI:MGI:1343468 +27552 D5Buc7 MGI:MGI:1343473 +27553 D5Buc6 MGI:MGI:1343496 +27562 D5Buc19 MGI:MGI:1343462 +27563 D5Buc28 MGI:MGI:1343465 +27564 D5Buc38 MGI:MGI:1343466 +27565 D5Buc18 MGI:MGI:1343469 +27566 D5Buc36 MGI:MGI:1343470 +27567 D5Buc29 MGI:MGI:1343471 +27568 D5Buc37 MGI:MGI:1343472 +27569 D5Buc35 MGI:MGI:1343475 +27570 D5Buc25 MGI:MGI:1343476 +27571 D5Buc11 MGI:MGI:1343477 +27572 D5Buc27 MGI:MGI:1343478 +27573 D5Buc21 MGI:MGI:1343480 +27574 D5Buc22 MGI:MGI:1343481 +27575 D5Buc23 MGI:MGI:1343482 +27576 D5Buc17 MGI:MGI:1343483 +27577 D5Buc16 MGI:MGI:1343484 +27578 D5Buc34 MGI:MGI:1343486 +27579 D5Buc10 MGI:MGI:1343487 +27580 D5Buc20 MGI:MGI:1343488 +27581 D5Buc12 MGI:MGI:1343490 +27582 D5Buc32 MGI:MGI:1343491 +27583 D5Buc15 MGI:MGI:1343492 +27584 D5Buc14 MGI:MGI:1343493 +27585 D5Buc13 MGI:MGI:1343494 +27586 D5Buc33 MGI:MGI:1343495 +27587 D5Buc31 MGI:MGI:1343497 +27590 D4Pel1 MGI:MGI:1330269 +27591 D15H22S992E MGI:MGI:1349418 +27594 EST974366 MGI:MGI:1349401 +27598 D11Bhm188 MGI:MGI:109399 +27599 D11Bhm107 MGI:MGI:106894 +27600 D0Dcr7 MGI:MGI:1309454 +27601 D0Dcr6 MGI:MGI:1309455 +27602 D0Dcr5 MGI:MGI:1309456 +27603 D0Dcr4 MGI:MGI:1309457 +27604 D0Dcr3 MGI:MGI:1309458 +27605 D0Dcr2 MGI:MGI:1309459 +27606 D0Dcr1 MGI:MGI:1309460 +27607 D0Dcr9 MGI:MGI:1309461 +27608 D17Leh89 MGI:MGI:90728 +27609 D6Rp2 MGI:MGI:93826 +27610 D0Hgu1 MGI:MGI:99219 +27611 D0Hgu2 MGI:MGI:99227 +27612 D0Hgu3 MGI:MGI:99228 +27613 D0Hgu4 MGI:MGI:99229 +27614 D0Hgu5 MGI:MGI:99230 +27615 D0Hgu6 MGI:MGI:99231 +27616 D0Hgu7 MGI:MGI:99232 +27617 D0Hgu8 MGI:MGI:99233 +27618 D0Hgu9 MGI:MGI:99234 +27620 D17Tu49 MGI:MGI:90990 +27621 D11Moh9 MGI:MGI:1343107 +27622 D11Moh8 MGI:MGI:1343108 +27623 D11Moh5 MGI:MGI:1343110 +27624 D11Moh4 MGI:MGI:1343111 +27625 D11Moh7 MGI:MGI:1343112 +27626 D11Moh6 MGI:MGI:1343113 +27627 D11Moh1 MGI:MGI:1343114 +27628 D11Moh3 MGI:MGI:1343115 +27629 D11Moh2 MGI:MGI:1343116 +27630 D17Leh467 MGI:MGI:90704 +27631 D17Leh525 MGI:MGI:90712 +27632 Nelfe MGI:MGI:102744|Ensembl:ENSMUSG00000024369|Vega:OTTMUSG00000037262 +27633 D0Dcr12 MGI:MGI:1309492 +27634 D0Dcr11 MGI:MGI:1309493 +27635 D0Dcr10 MGI:MGI:1309494 +27636 D0Dcr13 MGI:MGI:1310010 +27637 D13Die28 MGI:MGI:1347079 +27638 D13Die26 MGI:MGI:1347087 +27639 D13Die27 MGI:MGI:1347088 +27640 D13Die24 MGI:MGI:1347089 +27641 D13Die25 MGI:MGI:1347091 +27642 DXHXS1104 MGI:MGI:95044 +27643 Ubl4a MGI:MGI:95049|Ensembl:ENSMUSG00000015290|Vega:OTTMUSG00000017660 +27644 D0Hgu10 MGI:MGI:99220 +27645 D0Hgu11 MGI:MGI:99221 +27646 D0Hgu12 MGI:MGI:99222 +27647 D0Hgu13 MGI:MGI:99223 +27648 D0Hgu14 MGI:MGI:99224 +27649 D0Hgu15 MGI:MGI:99225 +27650 D0Hgu16 MGI:MGI:99226 +27651 D4Sh1 MGI:MGI:107748 +27652 D1Dau6 MGI:MGI:1346995 +27653 D1Dau9 MGI:MGI:1346996 +27654 D1Dau8 MGI:MGI:1346997 +27655 D1Dau1 MGI:MGI:1347065 +27656 D1Dau3 MGI:MGI:1347066 +27657 D1Dau2 MGI:MGI:1347067 +27658 D1Dau5 MGI:MGI:1347068 +27659 D1Dau4 MGI:MGI:1347069 +27660 1700088E04Rik MGI:MGI:1920774|Ensembl:ENSMUSG00000033029|Vega:OTTMUSG00000045321 +27666 D11Moh31 MGI:MGI:1343137 +27667 D11Moh20 MGI:MGI:1343143 +27668 D11Moh21 MGI:MGI:1343144 +27669 D11Moh22 MGI:MGI:1343145 +27670 D11Moh23 MGI:MGI:1343146 +27671 D11Moh25 MGI:MGI:1343148 +27672 D11Moh26 MGI:MGI:1343149 +27673 D11Moh27 MGI:MGI:1343150 +27674 D11Moh28 MGI:MGI:1343151 +27675 D11Moh29 MGI:MGI:1343152 +27676 D11Moh33 MGI:MGI:1343155 +27677 D11Moh32 MGI:MGI:1343156 +27678 D11Moh30 MGI:MGI:1343158 +27681 Snf8 MGI:MGI:1343161|Ensembl:ENSMUSG00000006058|Vega:OTTMUSG00000001957 +27682 D11Moh19 MGI:MGI:1343164 +27683 D11Moh18 MGI:MGI:1343165 +27684 D11Moh11 MGI:MGI:1343168 +27685 D11Moh10 MGI:MGI:1343169 +27686 D11Moh13 MGI:MGI:1343170 +27687 D11Moh12 MGI:MGI:1343171 +27688 D11Moh15 MGI:MGI:1343172 +27689 D11Moh14 MGI:MGI:1343173 +27690 D11Moh17 MGI:MGI:1343174 +27691 D11Moh16 MGI:MGI:1343175 +27694 D13Rp4 MGI:MGI:108217 +27695 D13Rp3 MGI:MGI:893594 +27696 D16Ros1 MGI:MGI:90606 +27697 23H6.T7 MGI:MGI:1342303 +27698 30B5.T7 MGI:MGI:1342305 +27699 D1Dau15 MGI:MGI:1347015 +27700 D1Dau14 MGI:MGI:1347016 +27701 D1Dau17 MGI:MGI:1347017 +27702 D1Dau16 MGI:MGI:1347018 +27703 D1Dau11 MGI:MGI:1347019 +27704 D1Dau10 MGI:MGI:1347020 +27705 D1Dau12 MGI:MGI:1347021 +27706 D1Dau19 MGI:MGI:1347024 +27707 D1Dau18 MGI:MGI:1347025 +27708 D1Dau28 MGI:MGI:1347026 +27709 D1Dau29 MGI:MGI:1347027 +27710 D1Dau33 MGI:MGI:1347028 +27711 D1Dau32 MGI:MGI:1347029 +27712 D1Dau20 MGI:MGI:1347030 +27713 D1Dau30 MGI:MGI:1347031 +27714 D1Dau22 MGI:MGI:1347032 +27715 D1Dau23 MGI:MGI:1347033 +27716 D1Dau24 MGI:MGI:1347034 +27717 D1Dau34 MGI:MGI:1347035 +27718 D1Dau26 MGI:MGI:1347036 +27719 D1Dau27 MGI:MGI:1347037 +27720 D1Dau31 MGI:MGI:1347039 +27721 D1Dau25 MGI:MGI:1347051 +27722 D1Sta9 MGI:MGI:1334449 +27723 D1Sta8 MGI:MGI:1334450 +27724 D1Sta5 MGI:MGI:1334451 +27725 D1Sta4 MGI:MGI:1334452 +27726 D1Sta7 MGI:MGI:1334453 +27727 D1Sta6 MGI:MGI:1334454 +27728 D1Sta1 MGI:MGI:1334455 +27729 D1Sta3 MGI:MGI:1334456 +27730 D1Sta2 MGI:MGI:1334457 +27731 D17Tu49a MGI:MGI:1337301 +27732 D17Tu49b MGI:MGI:1337302 +27733 D17Tu49c MGI:MGI:1337303 +27736 D1Ncl2 MGI:MGI:1277175 +27737 D1Ncl3 MGI:MGI:1330283 +27738 245A8.T7 MGI:MGI:1342280 +27739 254L6.T7 MGI:MGI:1342285 +27740 23H6.Sp6 MGI:MGI:1342289 +27741 210N7.T7 MGI:MGI:1342301 +27742 D2Dcr20 MGI:MGI:1309497 +27743 D2Dcr22 MGI:MGI:1309499 +27744 D2Dcr23 MGI:MGI:1309500 +27745 D2Dcr19 MGI:MGI:1309501 +27746 D2Dcr18 MGI:MGI:1309502 +27747 D2Dcr15 MGI:MGI:1309508 +27748 D2Dcr14 MGI:MGI:1309509 +27749 D2Dcr17 MGI:MGI:1309510 +27750 D2Dcr16 MGI:MGI:1309527 +27751 D1Sta11 MGI:MGI:1334439 +27752 D1Sta10 MGI:MGI:1334440 +27753 D1Sta13 MGI:MGI:1334441 +27754 D1Sta12 MGI:MGI:1334442 +27755 D1Sta14 MGI:MGI:1334443 +27756 Lsm2 MGI:MGI:90676|Ensembl:ENSMUSG00000007050|Vega:OTTMUSG00000037141 +27758 D6Abb1e MGI:MGI:106471 +27759 D2Abb1e MGI:MGI:106569 +27760 D5Abb2e MGI:MGI:107747 +27761 D2Abb3e MGI:MGI:107751 +27762 Vwa7 MGI:MGI:1306798|Ensembl:ENSMUSG00000007030|Vega:OTTMUSG00000033048 +27765 196D11.T7 MGI:MGI:1342271 +27766 273G21.T7 MGI:MGI:1342272 +27767 295F16.T7 MGI:MGI:1342275 +27768 332I15.T7 MGI:MGI:1342306 +27770 42J20R MGI:MGI:1341791 +27771 42J20F MGI:MGI:1341798 +27772 38B16F MGI:MGI:1341816 +27773 38B16R MGI:MGI:1341829 +27774 94B16F MGI:MGI:1341835 +27775 sWSS86 MGI:MGI:1341845 +27776 94B16R MGI:MGI:1341854 +27777 03B03F MGI:MGI:1341858 +27778 03B03R MGI:MGI:1341869 +27779 57K16F MGI:MGI:1341874 +27780 92N10R MGI:MGI:1341875 +27781 57K16R MGI:MGI:1341882 +27782 92N10F MGI:MGI:1341883 +27784 Commd8 MGI:MGI:1343485|Ensembl:ENSMUSG00000029213|Vega:OTTMUSG00000054289 +27785 D5Buc30e MGI:MGI:1343499 +27789 565M12F MGI:MGI:1341825 +27790 DXPas19 MGI:MGI:95198 +27791 D18Abb2e MGI:MGI:106270 +27792 D14Abb2e MGI:MGI:107723 +27793 D2Dcr4 MGI:MGI:1309520 +27794 D2Dcr7 MGI:MGI:1309521 +27795 D2Dcr3 MGI:MGI:1309525 +27796 D2Dcr9 MGI:MGI:1309532 +27797 D2Dcr8 MGI:MGI:1309533 +27798 D2Dcr5 MGI:MGI:1309534 +27799 D2Dcr6 MGI:MGI:1309535 +27800 D2Dcr2 MGI:MGI:1309536 +27801 Zdhhc8 MGI:MGI:1338012|Ensembl:ENSMUSG00000060166 +27804 502H20F MGI:MGI:1341810 +27805 303E12F MGI:MGI:1341811 +27806 502H20R MGI:MGI:1341815 +27807 303E12R MGI:MGI:1341820 +27808 119L04F MGI:MGI:1341824 +27809 565I03R MGI:MGI:1341827 +27810 358A17R MGI:MGI:1341832 +27811 304D23R MGI:MGI:1341838 +27812 304D23F MGI:MGI:1341842 +27813 133J02R MGI:MGI:1341846 +27814 256O10F MGI:MGI:1341849 +27815 391O16F MGI:MGI:1341852 +27816 256O10R MGI:MGI:1341855 +27817 133J02F MGI:MGI:1341856 +27818 349F04F MGI:MGI:1341861 +27819 391O16R MGI:MGI:1341862 +27820 349F04R MGI:MGI:1341871 +27821 504N12R MGI:MGI:1341885 +27822 565I03F MGI:MGI:1341887 +27823 211N06R MGI:MGI:1341893 +27824 504N12F MGI:MGI:1341895 +27825 567C18F MGI:MGI:1341899 +27826 211N06F MGI:MGI:1341901 +27827 335F15F MGI:MGI:1341904 +27828 335F15R MGI:MGI:1341913 +27829 D0Bac5 MGI:MGI:104584 +27830 D0Bac4 MGI:MGI:104585 +27831 D0Bac3 MGI:MGI:104586 +27832 D0Bac2 MGI:MGI:104587 +27833 D6Kcc1 MGI:MGI:107541 +27834 D2Dcr24 MGI:MGI:1309495 +27835 D2Dcr21 MGI:MGI:1309498 +27836 D2Dcr11 MGI:MGI:1309504 +27837 D2Dcr10 MGI:MGI:1309505 +27838 D2Dcr13 MGI:MGI:1309506 +27839 D2Dcr12 MGI:MGI:1309507 +27841 119L04aR MGI:MGI:1341812 +27842 D10Hgu1 MGI:MGI:104363 +27843 DXYHgu1 MGI:MGI:106237 +27844 DXSmh141 MGI:MGI:95219 +27845 D7Cwr3D MGI:MGI:102521 +27846 D0Nds6 MGI:MGI:88661 +27847 D0Nds7 MGI:MGI:88662 +27848 D0Nds8 MGI:MGI:88663 +27849 D0Nds9 MGI:MGI:88664 +27850 D5Nam12 MGI:MGI:103057 +27851 DXIum1 MGI:MGI:108098 +27852 D0Nds10 MGI:MGI:88634 +27853 D0Nds11 MGI:MGI:88635 +27854 D0Nds12 MGI:MGI:88636 +27855 D0Nds13 MGI:MGI:88637 +27856 D0Nds14 MGI:MGI:88638 +27857 D0Nds16 MGI:MGI:88640 +27858 D0Nds17 MGI:MGI:88641 +27859 D0Nds18 MGI:MGI:88642 +27860 D0Nds20 MGI:MGI:88643 +27861 D0Nds21 MGI:MGI:88644 +27862 D0Nds23 MGI:MGI:88645 +27863 D0Nds24 MGI:MGI:88646 +27864 D0Nds26 MGI:MGI:88647 +27865 D11Moh41e MGI:MGI:1343100 +27866 D11Moh37e MGI:MGI:1343105 +27867 D11Moh38e MGI:MGI:1343109 +27868 D11Moh42e MGI:MGI:1343121 +27870 D11Moh39e MGI:MGI:1343157 +27873 D16Smh250 MGI:MGI:90608 +27874 D16Smh580 MGI:MGI:90609 +27875 D17Ium1 MGI:MGI:108099 +27876 D1Dau7e MGI:MGI:1347038 +27878 Tada1 MGI:MGI:1196415|Ensembl:ENSMUSG00000026563|Vega:OTTMUSG00000026881 +27883 Tango2 MGI:MGI:101825|Ensembl:ENSMUSG00000013539|Vega:OTTMUSG00000026022 +27885 D9Mgc43 MGI:MGI:1330313 +27886 Dgcr14 MGI:MGI:107854|Ensembl:ENSMUSG00000003527 +27888 D16Ium77 MGI:MGI:106106 +27889 D16Ium76 MGI:MGI:106107 +27890 D16Ium75 MGI:MGI:106108 +27891 D16Ium74 MGI:MGI:106109 +27892 D16Ium73 MGI:MGI:106110 +27893 D16Ium72 MGI:MGI:106111 +27894 D16Ium71 MGI:MGI:106112 +27895 D16Ium70 MGI:MGI:106113 +27896 D16Ium69 MGI:MGI:106115 +27897 D16Ium68 MGI:MGI:106116 +27898 D16Ium67 MGI:MGI:106117 +27899 D16Ium66 MGI:MGI:106118 +27900 D16Ium65 MGI:MGI:106119 +27901 D16Ium64 MGI:MGI:106120 +27902 D16Ium63 MGI:MGI:106121 +27903 D16Ium62 MGI:MGI:106122 +27904 D16Ium61 MGI:MGI:106123 +27905 D16Ium60 MGI:MGI:106124 +27906 D16Ium59 MGI:MGI:106126 +27907 D16Ium58 MGI:MGI:106127 +27908 D16Ium57 MGI:MGI:106128 +27909 D16Ium56 MGI:MGI:106129 +27910 D16Ium55 MGI:MGI:106130 +27911 D16Ium54 MGI:MGI:106131 +27912 D16Ium53 MGI:MGI:106132 +27913 D16Ium52 MGI:MGI:106133 +27914 D16Ium51 MGI:MGI:106134 +27915 D16Ium50 MGI:MGI:106135 +27916 D16Ium49 MGI:MGI:106137 +27917 D16Ium48 MGI:MGI:106138 +27918 D16Ium47 MGI:MGI:106139 +27919 D16Ium46 MGI:MGI:106140 +27920 D16Ium45 MGI:MGI:106141 +27921 D16Ium44 MGI:MGI:106142 +27922 D16Ium43 MGI:MGI:106143 +27923 D16Ium42 MGI:MGI:106144 +27924 D16Ium41 MGI:MGI:106145 +27925 D16Ium40 MGI:MGI:106146 +27926 D0Ffm1 MGI:MGI:1306827 +27927 D0Ffm3 MGI:MGI:1306828 +27928 D0Ffm2 MGI:MGI:1306829 +27929 D0Ffm5 MGI:MGI:1306830 +27930 D0Ffm4 MGI:MGI:1306831 +27931 D0Ffm6 MGI:MGI:1306832 +27932 D1Nds1 MGI:MGI:91835 +27933 D1Nds2 MGI:MGI:91836 +27934 D2Nds1 MGI:MGI:92298 +27935 D3Nds1 MGI:MGI:92623 +27936 D3Nds2 MGI:MGI:92625 +27937 D3Nds3 MGI:MGI:92626 +27938 D3Nds7 MGI:MGI:92629 +27939 D4Nds2 MGI:MGI:93040 +27940 D5Nds1 MGI:MGI:93464 +27941 D5Nds2 MGI:MGI:93465 +27942 D7Nds1 MGI:MGI:94190 +27943 D7Nds2 MGI:MGI:94191 +27944 D9Nds2 MGI:MGI:94847 +27947 D10Nds1 MGI:MGI:88923 +27948 D10Nds2 MGI:MGI:88924 +27949 D11Nds1 MGI:MGI:89264 +27950 D13Nds1 MGI:MGI:89878 +27951 D14Nds5 MGI:MGI:90160 +27952 D15Nds1 MGI:MGI:90420 +27953 D16Nds2 MGI:MGI:90604 +27954 D6Uwa4 MGI:MGI:1096864 +27955 D16Nds1 MGI:MGI:90603 +27962 D9Wsu90e MGI:MGI:106400 +27963 D9Wsu74e MGI:MGI:106401 +27965 Spg21 MGI:MGI:106403|Ensembl:ENSMUSG00000032388|Vega:OTTMUSG00000062631 +27966 Rrp9 MGI:MGI:2384313|Ensembl:ENSMUSG00000041506|Vega:OTTMUSG00000033577 +27967 Cherp MGI:MGI:106417|Ensembl:ENSMUSG00000052488|Vega:OTTMUSG00000062111 +27971 D8Wsu26e MGI:MGI:106421 +27973 Vkorc1 MGI:MGI:106442|Ensembl:ENSMUSG00000096145|Vega:OTTMUSG00000031112 +27974 D7Wsu69e MGI:MGI:106443 +27979 Eif3b MGI:MGI:106478|Ensembl:ENSMUSG00000056076|Vega:OTTMUSG00000054815 +27981 Rsrp1 MGI:MGI:106498|Ensembl:ENSMUSG00000037266|Vega:OTTMUSG00000011095 +27984 Efhd2 MGI:MGI:106504|Ensembl:ENSMUSG00000040659|Vega:OTTMUSG00000010040 +27986 D3Wsu79e MGI:MGI:106519 +27993 Imp4 MGI:MGI:106572|Ensembl:ENSMUSG00000026127|Vega:OTTMUSG00000029577 +27995 D16Ium7e MGI:MGI:106114 +27996 D2Wsu85e MGI:MGI:106543 +27997 D4Wsu139e MGI:MGI:107327 +27998 Exosc5 MGI:MGI:107889|Ensembl:ENSMUSG00000061286|Vega:OTTMUSG00000058396 +27999 Fam3c MGI:MGI:107892|Ensembl:ENSMUSG00000029672|Vega:OTTMUSG00000035360 +28000 Prpf19 MGI:MGI:106247|Ensembl:ENSMUSG00000024735|Vega:OTTMUSG00000046847 +28006 Washc2 MGI:MGI:106463|Ensembl:ENSMUSG00000024104|Vega:OTTMUSG00000056774 +28010 Miip MGI:MGI:106506|Ensembl:ENSMUSG00000029022|Vega:OTTMUSG00000010653 +28011 D3Wsu106e MGI:MGI:106521 +28012 D2Wsu107e MGI:MGI:106551 +28014 D9Wsu149 MGI:MGI:107281 +28015 Polr2m MGI:MGI:107282|Ensembl:ENSMUSG00000032199|Vega:OTTMUSG00000036049 +28017 D7Wsu130e MGI:MGI:107300 +28018 Ubfd1 MGI:MGI:107301|Ensembl:ENSMUSG00000030870|Vega:OTTMUSG00000025468 +28019 Ing4 MGI:MGI:107307|Ensembl:ENSMUSG00000030330|Vega:OTTMUSG00000024325 +28022 D5Wsu152e MGI:MGI:107316 +28024 D5Wsu148e MGI:MGI:107318 +28028 Mrpl50 MGI:MGI:107329|Ensembl:ENSMUSG00000044018|Vega:OTTMUSG00000008320 +28030 Gfm1 MGI:MGI:107339|Ensembl:ENSMUSG00000027774|Vega:OTTMUSG00000029074 +28035 Usp39 MGI:MGI:107622|Ensembl:ENSMUSG00000056305|Vega:OTTMUSG00000023516 +28036 Larp7 MGI:MGI:107634|Ensembl:ENSMUSG00000027968|Vega:OTTMUSG00000052794 +28037 D1Wsu158e MGI:MGI:107648 +28040 D6Wsu163e MGI:MGI:107893|Ensembl:ENSMUSG00000030347|Vega:OTTMUSG00000056339 +28042 Selenoi MGI:MGI:107898|Ensembl:ENSMUSG00000075703|Vega:OTTMUSG00000033213 +28043 D3Wsu174e MGI:MGI:107905 +28044 D3Wsu167e MGI:MGI:107906 +28045 D16Ium37e MGI:MGI:106150 +28046 D16Ium33e MGI:MGI:106154 +28047 D16Ium30e MGI:MGI:106157 +28049 D16Ium25e MGI:MGI:106162 +28050 D16Ium19e MGI:MGI:106168 +28051 D17Ium18e MGI:MGI:106169 +28052 D16Ium17e MGI:MGI:106170 +28054 D16Ium15e MGI:MGI:106172 +28055 D16Ium14e MGI:MGI:106173 +28056 D16Ium13e MGI:MGI:106174 +28057 D16Ium11e MGI:MGI:106176 +28060 D19Wsu44e MGI:MGI:106249 +28064 Yipf3 MGI:MGI:106280|Ensembl:ENSMUSG00000071074|Vega:OTTMUSG00000028839 +28071 Twistnb MGI:MGI:106292|Ensembl:ENSMUSG00000020561 +28075 Desi1 MGI:MGI:106313|Ensembl:ENSMUSG00000022472|Vega:OTTMUSG00000032775 +28077 Med10 MGI:MGI:106331|Ensembl:ENSMUSG00000021598 +28078 Prl5a1 MGI:MGI:106332|Ensembl:ENSMUSG00000017064|Vega:OTTMUSG00000000654 +28080 Atp5o MGI:MGI:106341|Ensembl:ENSMUSG00000022956|Vega:OTTMUSG00000026954 +28081 Fam104a MGI:MGI:106351|Ensembl:ENSMUSG00000041629|Vega:OTTMUSG00000003398 +28084 Vps25 MGI:MGI:106354|Ensembl:ENSMUSG00000078656|Vega:OTTMUSG00000002759 +28085 D11Wsu48e MGI:MGI:106355 +28088 Rtcb MGI:MGI:106379|Ensembl:ENSMUSG00000001783|Vega:OTTMUSG00000023233 +28091 DYzEms9 MGI:MGI:107828 +28092 DYzEms8 MGI:MGI:107829 +28093 DYzEms7 MGI:MGI:107830 +28094 DYzEms6 MGI:MGI:107831 +28095 DYzEms5 MGI:MGI:107832 +28096 DYzEms4 MGI:MGI:107833 +28097 DYzEms3 MGI:MGI:107834 +28098 DYzEms2 MGI:MGI:107835 +28099 DYzEms1 MGI:MGI:107839 +28105 Trim36 MGI:MGI:106264|Ensembl:ENSMUSG00000033949 +28106 Mydgf MGI:MGI:2156020|Ensembl:ENSMUSG00000019579|Vega:OTTMUSG00000028476 +28109 D10Wsu102e MGI:MGI:106381|Ensembl:ENSMUSG00000020255|Vega:OTTMUSG00000060613 +28112 D15Wsu126e MGI:MGI:107242 +28113 Tinf2 MGI:MGI:107246|Ensembl:ENSMUSG00000007589 +28114 Nsun2 MGI:MGI:107252|Ensembl:ENSMUSG00000021595|Vega:OTTMUSG00000024575 +28120 D10Wsu159e MGI:MGI:107604 +28123 D17Wsu164e MGI:MGI:107850 +28126 Nop16 MGI:MGI:107862|Ensembl:ENSMUSG00000025869|Vega:OTTMUSG00000032680 +28129 D11Wsu173e MGI:MGI:107872 +28132 D9Mgc42e MGI:MGI:1330230 +28133 D9Mgc40e MGI:MGI:1330234 +28134 D9Mgc45e MGI:MGI:1330261 +28135 Cep63 MGI:MGI:2158560|Ensembl:ENSMUSG00000032534|Vega:OTTMUSG00000034608 +28137 D9Mgc46e MGI:MGI:1330315 +28138 D7Ucla2 MGI:MGI:94220 +28139 DYzEms12 MGI:MGI:107836 +28140 DYzEms11 MGI:MGI:107837 +28141 DYzEms10 MGI:MGI:107838 +28146 Serp1 MGI:MGI:92638|Ensembl:ENSMUSG00000027808|Vega:OTTMUSG00000029383 +28148 D4Ucla1 MGI:MGI:93101 +28150 D5Ucla2 MGI:MGI:93473 +28154 D16Ium9e MGI:MGI:106102 +28155 D16Ium8e MGI:MGI:106103 +28156 D16Ium6e MGI:MGI:106125 +28157 D16Ium5e MGI:MGI:106136 +28159 DYzEms15 MGI:MGI:1097669 +28160 DYzEms14 MGI:MGI:1097670 +28161 DYzEms17 MGI:MGI:1097671 +28162 DYzEms16 MGI:MGI:1097672 +28163 DYzEms13 MGI:MGI:1097673 +28164 DYzEms21 MGI:MGI:1097674 +28165 DYzEms22 MGI:MGI:1097675 +28166 DYzEms19 MGI:MGI:1097678 +28167 DYzEms18 MGI:MGI:1097679 +28168 DYzEms20 MGI:MGI:1097690 +28169 Agpat3 MGI:MGI:1336186|Ensembl:ENSMUSG00000001211|Vega:OTTMUSG00000020522 +28171 D6Wum8 MGI:MGI:1096552 +28173 D16Ium39e MGI:MGI:106148 +28174 D16Ium38e MGI:MGI:106149 +28175 D16Ium36e MGI:MGI:106151 +28176 D16Ium35e MGI:MGI:106152 +28177 D16Ium34e MGI:MGI:106153 +28178 D16Ium32e MGI:MGI:106155 +28179 D16Ium31e MGI:MGI:106156 +28180 D16Ium29e MGI:MGI:106158 +28181 D16Ium28e MGI:MGI:106159 +28182 D16Ium27e MGI:MGI:106160 +28184 D16Ium23e MGI:MGI:106164 +28185 Tomm70a MGI:MGI:106295|Ensembl:ENSMUSG00000022752 +28187 D16Ium20e MGI:MGI:106167 +28188 D16Ium12e MGI:MGI:106175 +28190 D6Wum2 MGI:MGI:1096578 +28191 D6Wum4 MGI:MGI:1096583 +28192 D6Wum9 MGI:MGI:1343136 +28193 Reep3 MGI:MGI:88930|Ensembl:ENSMUSG00000019873 +28194 Apon MGI:MGI:88931|Ensembl:ENSMUSG00000051716 +28199 Dcaf11 MGI:MGI:90168|Ensembl:ENSMUSG00000022214|Vega:OTTMUSG00000027921 +28200 Dhrs4 MGI:MGI:90169|Ensembl:ENSMUSG00000022210 +28205 D6Wum13 MGI:MGI:1343119 +28206 D6Wum14 MGI:MGI:1343125 +28207 D6Wum15 MGI:MGI:1343140 +28208 D6Wum20 MGI:MGI:1343182 +28209 D0Nrs2 MGI:MGI:1196352 +28210 D0Nrs1 MGI:MGI:1196353 +28211 D6Wum18 MGI:MGI:1343117 +28212 D6Wum12 MGI:MGI:1343120 +28213 D6Wum10 MGI:MGI:1343122 +28214 D6Wum16 MGI:MGI:1343123 +28240 Trpm2 MGI:MGI:1351901|Ensembl:ENSMUSG00000009292|Vega:OTTMUSG00000020526 +28248 Slco1a1 MGI:MGI:1351891|Ensembl:ENSMUSG00000041698|Vega:OTTMUSG00000036867 +28250 Slco1a4 MGI:MGI:1351896|Ensembl:ENSMUSG00000030237|Vega:OTTMUSG00000036818 +28253 Slco1b2 MGI:MGI:1351899|Ensembl:ENSMUSG00000030236|Vega:OTTMUSG00000025596 +28254 Slco1a6 MGI:MGI:1351906|Ensembl:ENSMUSG00000079262|Vega:OTTMUSG00000037058 +28255 D11Moh24 MGI:MGI:1343147 +28256 D10Jhu45 MGI:MGI:1351855 +28257 D10Jhu42 MGI:MGI:1351856 +28258 D10Jhu41 MGI:MGI:1351859 +28259 D10Jhu60 MGI:MGI:1351860 +28260 D10Jhu52 MGI:MGI:1351864 +28261 D10Jhu54 MGI:MGI:1351868 +28262 D10Jhu59 MGI:MGI:1351870 +28263 D10Jhu58 MGI:MGI:1351871 +28264 D10Jhu51 MGI:MGI:1351874 +28265 D10Jhu50 MGI:MGI:1351875 +28266 D10Jhu39 MGI:MGI:1351876 +28267 D10Jhu61 MGI:MGI:1351877 +28268 D10Jhu37 MGI:MGI:1351878 +28269 D10Jhu36 MGI:MGI:1351879 +28270 D10Jhu35 MGI:MGI:1351880 +28271 D10Jhu56 MGI:MGI:1351881 +28272 D10Jhu33 MGI:MGI:1351882 +28273 D10Jhu67 MGI:MGI:1351883 +28274 D10Jhu68 MGI:MGI:1351884 +28275 D10Jhu69 MGI:MGI:1351885 +28276 D10Jhu40 MGI:MGI:1351886 +28277 D10Jhu79 MGI:MGI:1351888 +28278 D10Jhu78 MGI:MGI:1351889 +28279 D10Jhu48 MGI:MGI:1351892 +28280 D10Jhu49 MGI:MGI:1351893 +28281 D10Jhu43 MGI:MGI:1351895 +28282 D10Jhu72 MGI:MGI:1351898 +28283 D10Jhu53 MGI:MGI:1351900 +28284 D10Jhu46 MGI:MGI:1351902 +28285 D10Jhu38 MGI:MGI:1351903 +28286 D10Jhu47 MGI:MGI:1351904 +28287 D10Jhu55 MGI:MGI:1351905 +28288 D10Jhu63 MGI:MGI:1351907 +28289 D10Jhu65 MGI:MGI:1351908 +28290 D10Jhu57 MGI:MGI:1351909 +28291 D10Jhu70 MGI:MGI:1351910 +28292 D10Jhu44 MGI:MGI:1351913 +28293 D10Jhu66 MGI:MGI:1351914 +28294 D10Jhu71e MGI:MGI:1351857 +28295 D10Jhu81e MGI:MGI:1351861|Ensembl:ENSMUSG00000053329 +28296 D10Jhu64e MGI:MGI:1351887 +28297 D10Jhu34e MGI:MGI:1351897 +29805 Znhit2 MGI:MGI:1352481|Ensembl:ENSMUSG00000075227|Vega:OTTMUSG00000028978 +29806 Limd1 MGI:MGI:1352502|Ensembl:ENSMUSG00000025239|Vega:OTTMUSG00000062848 +29807 Tpk1 MGI:MGI:1352500|Ensembl:ENSMUSG00000029735|Vega:OTTMUSG00000023547 +29808 Mga MGI:MGI:1352483|Ensembl:ENSMUSG00000033943|Vega:OTTMUSG00000015288 +29809 Rabgap1l MGI:MGI:1352507|Ensembl:ENSMUSG00000026721|Vega:OTTMUSG00000050683 +29810 Bag3 MGI:MGI:1352493|Ensembl:ENSMUSG00000030847|Vega:OTTMUSG00000058717 +29811 Ndrg2 MGI:MGI:1352498|Ensembl:ENSMUSG00000004558 +29812 Ndrg3 MGI:MGI:1352499|Ensembl:ENSMUSG00000027634|Vega:OTTMUSG00000016170 +29813 Zfp385a MGI:MGI:1352495|Ensembl:ENSMUSG00000000552 +29815 Bcar3 MGI:MGI:1352501|Ensembl:ENSMUSG00000028121|Vega:OTTMUSG00000052422 +29816 Hip1r MGI:MGI:1352504|Ensembl:ENSMUSG00000000915|Vega:OTTMUSG00000035912 +29817 Igfbp7 MGI:MGI:1352480|Ensembl:ENSMUSG00000036256|Vega:OTTMUSG00000056133 +29818 Hspb7 MGI:MGI:1352494|Ensembl:ENSMUSG00000006221|Vega:OTTMUSG00000010297 +29819 Stau2 MGI:MGI:1352508|Ensembl:ENSMUSG00000025920|Vega:OTTMUSG00000033135 +29820 Tnfrsf19 MGI:MGI:1352474|Ensembl:ENSMUSG00000060548 +29821 Del(X)4Brd MGI:MGI:1352478 +29822 Del(X)3Brd MGI:MGI:1352487 +29823 Del(X)1Brd MGI:MGI:1352492 +29824 Del(X)2Brd MGI:MGI:1352510 +29825 Del(X)18Brd MGI:MGI:1352475 +29826 Del(X)16Brd MGI:MGI:1352479 +29827 Del(X)19Brd MGI:MGI:1352482 +29828 Del(X)17Brd MGI:MGI:1352497 +29829 Del(11)1Brd MGI:MGI:1352506 +29830 Del(11)9Brd MGI:MGI:1352511 +29831 Del(11)14Brd MGI:MGI:1352484 +29832 Del(11)13Brd MGI:MGI:1352485 +29833 Del(11)12Brd MGI:MGI:1352488 +29834 Del(11)10Brd MGI:MGI:1352489 +29835 Del(11)11Brd MGI:MGI:1352491 +29836 Del(11)15Brd MGI:MGI:1352496 +29837 Del(11)16Brd MGI:MGI:1352505 +29845 Olfr155 MGI:MGI:1352681|Ensembl:ENSMUSG00000071000|Vega:OTTMUSG00000007128 +29846 Olfr156 MGI:MGI:1352683|Ensembl:ENSMUSG00000110970|Vega:OTTMUSG00000007129 +29848 Olfr29-ps1 MGI:MGI:1352685|Ensembl:ENSMUSG00000111338|Vega:OTTMUSG00000007132 +29849 Olfr159 MGI:MGI:1352686|Ensembl:ENSMUSG00000044801|Vega:OTTMUSG00000007134 +29856 Smtn MGI:MGI:1354727|Ensembl:ENSMUSG00000020439|Vega:OTTMUSG00000005025 +29857 Mapk12 MGI:MGI:1353438|Ensembl:ENSMUSG00000022610 +29858 Pmm1 MGI:MGI:1353418|Ensembl:ENSMUSG00000022474|Vega:OTTMUSG00000028155 +29859 Sult4a1 MGI:MGI:1888971|Ensembl:ENSMUSG00000018865 +29861 Dpf1 MGI:MGI:1352748|Ensembl:ENSMUSG00000030584|Vega:OTTMUSG00000025006 +29862 Ninj2 MGI:MGI:1352751|Ensembl:ENSMUSG00000041377|Vega:OTTMUSG00000023350 +29863 Pde7b MGI:MGI:1352752|Ensembl:ENSMUSG00000019990|Vega:OTTMUSG00000036894 +29864 Rnf11 MGI:MGI:1352759|Ensembl:ENSMUSG00000028557|Vega:OTTMUSG00000008287 +29865 Cabp5 MGI:MGI:1352746|Ensembl:ENSMUSG00000005649|Vega:OTTMUSG00000027135 +29866 Cabp2 MGI:MGI:1352749|Ensembl:ENSMUSG00000024857|Vega:OTTMUSG00000034965 +29867 Cabp1 MGI:MGI:1352750|Ensembl:ENSMUSG00000029544|Vega:OTTMUSG00000014631 +29869 Ulk2 MGI:MGI:1352758|Ensembl:ENSMUSG00000004798|Vega:OTTMUSG00000005846 +29870 Gtse1 MGI:MGI:1352755|Ensembl:ENSMUSG00000022385 +29871 Scmh1 MGI:MGI:1352762|Ensembl:ENSMUSG00000000085|Vega:OTTMUSG00000008809 +29873 Cspg5 MGI:MGI:1352747|Ensembl:ENSMUSG00000032482|Vega:OTTMUSG00000051478 +29875 Iqgap1 MGI:MGI:1352757|Ensembl:ENSMUSG00000030536|Vega:OTTMUSG00000058690 +29876 Clic4 MGI:MGI:1352754|Ensembl:ENSMUSG00000037242|Vega:OTTMUSG00000009685 +29877 Hdgfl3 MGI:MGI:1352760|Ensembl:ENSMUSG00000025104|Vega:OTTMUSG00000024604 +29879 l7Rl2 MGI:MGI:1352764 +30003 D10Jhu7 MGI:MGI:1316705 +30004 D10Jhu8 MGI:MGI:1316734 +30005 D10Jhu16 MGI:MGI:1336204 +30006 D10Jhu11e MGI:MGI:1316716 +30007 D10Mit174 MGI:MGI:88796 +30044 Opn4 MGI:MGI:1353425|Ensembl:ENSMUSG00000021799 +30045 Dnajc12 MGI:MGI:1353428|Ensembl:ENSMUSG00000036764|Vega:OTTMUSG00000030793 +30046 Zfp292 MGI:MGI:1353423|Ensembl:ENSMUSG00000039967|Vega:OTTMUSG00000006461 +30049 Scd3 MGI:MGI:1353437|Ensembl:ENSMUSG00000025202 +30050 Fbxw2 MGI:MGI:1353435|Ensembl:ENSMUSG00000035949|Vega:OTTMUSG00000012022 +30051 Spdef MGI:MGI:1353422|Ensembl:ENSMUSG00000024215|Vega:OTTMUSG00000021352 +30052 Pcsk1n MGI:MGI:1353431|Ensembl:ENSMUSG00000039278|Vega:OTTMUSG00000018013 +30053 Reg3d MGI:MGI:1353426|Ensembl:ENSMUSG00000068341|Vega:OTTMUSG00000057463 +30054 Rnf17 MGI:MGI:1353419|Ensembl:ENSMUSG00000000365 +30055 Timm13 MGI:MGI:1353432|Ensembl:ENSMUSG00000020219 +30056 Timm9 MGI:MGI:1353436|Ensembl:ENSMUSG00000021079 +30057 Timm8b MGI:MGI:1353424|Ensembl:ENSMUSG00000039016|Vega:OTTMUSG00000063073 +30058 Timm8a1 MGI:MGI:1353433|Ensembl:ENSMUSG00000048007|Vega:OTTMUSG00000019308 +30059 Timm10 MGI:MGI:1353429|Ensembl:ENSMUSG00000027076|Vega:OTTMUSG00000013727 +30060 Meltf MGI:MGI:1353421|Ensembl:ENSMUSG00000022780 +30785 Cttnbp2 MGI:MGI:1353467|Ensembl:ENSMUSG00000000416|Vega:OTTMUSG00000024169 +30791 Slc39a1 MGI:MGI:1353474|Ensembl:ENSMUSG00000052310|Vega:OTTMUSG00000029569 +30794 Pdlim4 MGI:MGI:1353470|Ensembl:ENSMUSG00000020388|Vega:OTTMUSG00000005656 +30795 Fkbp3 MGI:MGI:1353460|Ensembl:ENSMUSG00000020949 +30800 Mmp20 MGI:MGI:1353466|Ensembl:ENSMUSG00000018620|Vega:OTTMUSG00000062304 +30805 Slc22a4 MGI:MGI:1353479|Ensembl:ENSMUSG00000020334|Vega:OTTMUSG00000005654 +30806 Adamts8 MGI:MGI:1353468|Ensembl:ENSMUSG00000031994|Vega:OTTMUSG00000034192 +30821 DXChri1 MGI:MGI:1353407 +30822 DXChri2 MGI:MGI:1353408 +30823 DXChri3 MGI:MGI:1353409 +30824 DXChri4 MGI:MGI:1353410 +30825 DXChri5 MGI:MGI:1353411 +30838 Fbxw4 MGI:MGI:1354698|Ensembl:ENSMUSG00000040913|Vega:OTTMUSG00000034259 +30839 Fbxw5 MGI:MGI:1354731|Ensembl:ENSMUSG00000015095|Vega:OTTMUSG00000012119 +30840 Fbxl6 MGI:MGI:1354705|Ensembl:ENSMUSG00000022559 +30841 Kdm2b MGI:MGI:1354737|Ensembl:ENSMUSG00000029475|Vega:OTTMUSG00000055467 +30843 Fbxl12 MGI:MGI:1354738|Ensembl:ENSMUSG00000066892|Vega:OTTMUSG00000029129 +30853 Mlf2 MGI:MGI:1353554|Ensembl:ENSMUSG00000030120|Vega:OTTMUSG00000056694 +30857 C77218 MGI:MGI:1353602 +30858 C78205 MGI:MGI:1353603 +30862 C78135 MGI:MGI:1353649 +30863 C78662 MGI:MGI:1353663 +30865 C78513 MGI:MGI:1353579 +30872 C76453 MGI:MGI:1353618 +30873 C77614 MGI:MGI:1353626 +30874 C77488 MGI:MGI:1353632 +30877 Gnl3 MGI:MGI:1353651|Ensembl:ENSMUSG00000042354 +30878 Apln MGI:MGI:1353624|Ensembl:ENSMUSG00000037010|Vega:OTTMUSG00000017506 +30882 AI256707 MGI:MGI:1353564 +30896 AI225873 MGI:MGI:1353614 +30910 C230037E05Rik MGI:MGI:1353666 +30912 AI317230 MGI:MGI:1353570 +30914 AI317185 MGI:MGI:1353591 +30917 AI256787 MGI:MGI:1353630 +30919 AI316844 MGI:MGI:1353641 +30921 A730014G21Rik MGI:MGI:1353646 +30923 Foxe3 MGI:MGI:1353569|Ensembl:ENSMUSG00000044518|Vega:OTTMUSG00000008588 +30924 Angptl3 MGI:MGI:1353627|Ensembl:ENSMUSG00000028553|Vega:OTTMUSG00000008051 +30925 Slamf6 MGI:MGI:1353620|Ensembl:ENSMUSG00000015314|Vega:OTTMUSG00000050091 +30926 Glrx3 MGI:MGI:1353653|Ensembl:ENSMUSG00000031068|Vega:OTTMUSG00000060317 +30927 Snai3 MGI:MGI:1353563|Ensembl:ENSMUSG00000006587|Vega:OTTMUSG00000061849 +30928 Zbtb18 MGI:MGI:1353609|Ensembl:ENSMUSG00000063659|Vega:OTTMUSG00000050359 +30930 Vps26a MGI:MGI:1353654|Ensembl:ENSMUSG00000020078 +30931 Tor1a MGI:MGI:1353568|Ensembl:ENSMUSG00000026849|Vega:OTTMUSG00000011870 +30932 Zfp330 MGI:MGI:1353574|Ensembl:ENSMUSG00000031711|Vega:OTTMUSG00000061382 +30933 Tor2a MGI:MGI:1353596|Ensembl:ENSMUSG00000009563|Vega:OTTMUSG00000012535 +30934 Tor1b MGI:MGI:1353605|Ensembl:ENSMUSG00000026848|Vega:OTTMUSG00000011877 +30935 Tor3a MGI:MGI:1353652|Ensembl:ENSMUSG00000060519|Vega:OTTMUSG00000021567 +30936 Slc46a2 MGI:MGI:1353616|Ensembl:ENSMUSG00000028386|Vega:OTTMUSG00000007404 +30937 Lmcd1 MGI:MGI:1353635|Ensembl:ENSMUSG00000057604|Vega:OTTMUSG00000021202 +30938 Fgd3 MGI:MGI:1353657|Ensembl:ENSMUSG00000037946|Vega:OTTMUSG00000020966 +30939 Pttg1 MGI:MGI:1353578|Ensembl:ENSMUSG00000020415|Vega:OTTMUSG00000005453 +30940 Usp25 MGI:MGI:1353655|Ensembl:ENSMUSG00000022867 +30941 Usp21 MGI:MGI:1353665|Ensembl:ENSMUSG00000053483|Vega:OTTMUSG00000021702 +30942 Hnf4g MGI:MGI:1353604|Ensembl:ENSMUSG00000017688|Vega:OTTMUSG00000020282 +30943 Prss30 MGI:MGI:1353645|Ensembl:ENSMUSG00000024124|Vega:OTTMUSG00000023161 +30944 Zfp354c MGI:MGI:1353621|Ensembl:ENSMUSG00000044807|Vega:OTTMUSG00000007885 +30945 Rnf19a MGI:MGI:1353623|Ensembl:ENSMUSG00000022280 +30946 Abt1 MGI:MGI:1353636|Ensembl:ENSMUSG00000036376|Vega:OTTMUSG00000000736 +30947 Adat1 MGI:MGI:1353631|Ensembl:ENSMUSG00000031949|Vega:OTTMUSG00000029927 +30948 Bin1 MGI:MGI:108092|Ensembl:ENSMUSG00000024381 +30949 Lcmt1 MGI:MGI:1353593|Ensembl:ENSMUSG00000030763|Vega:OTTMUSG00000058145 +30951 Cbx8 MGI:MGI:1353589|Ensembl:ENSMUSG00000025578|Vega:OTTMUSG00000003999 +30952 Cngb3 MGI:MGI:1353562|Ensembl:ENSMUSG00000056494|Vega:OTTMUSG00000004614 +30953 Schip1 MGI:MGI:1353557|Ensembl:ENSMUSG00000027777|Vega:OTTMUSG00000043622 +30954 Siva1 MGI:MGI:1353606|Ensembl:ENSMUSG00000064326 +30955 Pik3cg MGI:MGI:1353576|Ensembl:ENSMUSG00000020573|Vega:OTTMUSG00000033083 +30956 Aass MGI:MGI:1353573|Ensembl:ENSMUSG00000029695|Vega:OTTMUSG00000023540 +30957 Mapk8ip3 MGI:MGI:1353598|Ensembl:ENSMUSG00000024163|Vega:OTTMUSG00000030477 +30959 Ddx25 MGI:MGI:1353582|Ensembl:ENSMUSG00000032101|Vega:OTTMUSG00000044699 +30960 Vapa MGI:MGI:1353561|Ensembl:ENSMUSG00000024091 +30962 Slc7a9 MGI:MGI:1353656|Ensembl:ENSMUSG00000030492|Vega:OTTMUSG00000031618 +30963 Hacd1 MGI:MGI:1353592|Ensembl:ENSMUSG00000063275|Vega:OTTMUSG00000011400 +30964 Rps12-ps1 MGI:MGI:1353638 +50490 Nox4 MGI:MGI:1354184|Ensembl:ENSMUSG00000030562|Vega:OTTMUSG00000021141 +50492 Thop1 MGI:MGI:1354165|Ensembl:ENSMUSG00000004929|Vega:OTTMUSG00000035441 +50493 Txnrd1 MGI:MGI:1354175|Ensembl:ENSMUSG00000020250 +50496 E2f6 MGI:MGI:1354159|Ensembl:ENSMUSG00000057469 +50497 Hspa14 MGI:MGI:1354164|Ensembl:ENSMUSG00000051396|Ensembl:ENSMUSG00000109865|Vega:OTTMUSG00000010780|Vega:OTTMUSG00000060247 +50498 Ebi3 MGI:MGI:1354171|Ensembl:ENSMUSG00000003206 +50500 Ttpa MGI:MGI:1354168|Ensembl:ENSMUSG00000073988|Vega:OTTMUSG00000006384 +50501 Prok2 MGI:MGI:1354178|Ensembl:ENSMUSG00000030069|Vega:OTTMUSG00000057660 +50505 Ercc4 MGI:MGI:1354163|Ensembl:ENSMUSG00000022545|Vega:OTTMUSG00000024311 +50510 Igk-Eik MGI:MGI:1354193 +50518 a MGI:MGI:87853|Ensembl:ENSMUSG00000027596|Ensembl:ENSMUSG00000084897|Vega:OTTMUSG00000015981|Vega:OTTMUSG00000016002 +50523 Lats2 MGI:MGI:1354386|Ensembl:ENSMUSG00000021959|Vega:OTTMUSG00000037614 +50524 Sall2 MGI:MGI:1354373|Ensembl:ENSMUSG00000049532|Vega:OTTMUSG00000023347 +50525 Spag6l MGI:MGI:1354388|Ensembl:ENSMUSG00000022783|Vega:OTTMUSG00000025639 +50527 Ero1l MGI:MGI:1354385|Ensembl:ENSMUSG00000021831 +50528 Tmprss2 MGI:MGI:1354381|Ensembl:ENSMUSG00000000385 +50529 Mrps7 MGI:MGI:1354367|Ensembl:ENSMUSG00000046756|Vega:OTTMUSG00000003473 +50530 Mfap5 MGI:MGI:1354387|Ensembl:ENSMUSG00000030116|Vega:OTTMUSG00000024360 +50540 Igbp1b MGI:MGI:1354380|Ensembl:ENSMUSG00000046717|Vega:OTTMUSG00000057640 +50701 Elane MGI:MGI:2679229|Ensembl:ENSMUSG00000020125 +50702 Cfhr1 MGI:MGI:2138169|Ensembl:ENSMUSG00000057037|Vega:OTTMUSG00000034842 +50706 Postn MGI:MGI:1926321|Ensembl:ENSMUSG00000027750|Vega:OTTMUSG00000029043 +50708 Hist1h1c MGI:MGI:1931526|Ensembl:ENSMUSG00000036181|Vega:OTTMUSG00000000732 +50709 Hist1h1e MGI:MGI:1931527|Ensembl:ENSMUSG00000051627|Vega:OTTMUSG00000000564 +50720 Sacs MGI:MGI:1354724|Ensembl:ENSMUSG00000048279|Vega:OTTMUSG00000029987 +50721 Sirt6 MGI:MGI:1354161|Ensembl:ENSMUSG00000034748|Vega:OTTMUSG00000030471 +50722 Dkkl1 MGI:MGI:1354963|Ensembl:ENSMUSG00000030792|Vega:OTTMUSG00000058652 +50723 Icosl MGI:MGI:1354701|Ensembl:ENSMUSG00000000732 +50724 Sap30l MGI:MGI:1354709|Ensembl:ENSMUSG00000020519|Vega:OTTMUSG00000005710 +50740 AF007000 MGI:MGI:1354745 +50753 Fbxo8 MGI:MGI:1354696|Ensembl:ENSMUSG00000038206|Vega:OTTMUSG00000021103 +50754 Fbxw7 MGI:MGI:1354695|Ensembl:ENSMUSG00000028086|Vega:OTTMUSG00000022670 +50755 Fbxo18 MGI:MGI:1354699|Ensembl:ENSMUSG00000058594|Vega:OTTMUSG00000011294 +50757 Fbxw14 MGI:MGI:1354703|Ensembl:ENSMUSG00000105589|Vega:OTTMUSG00000027444 +50758 Fbxl17 MGI:MGI:1354704|Ensembl:ENSMUSG00000023965|Vega:OTTMUSG00000035637 +50759 Fbxo16 MGI:MGI:1354706|Ensembl:ENSMUSG00000034532 +50760 Fbxo17 MGI:MGI:1354707|Ensembl:ENSMUSG00000030598|Vega:OTTMUSG00000022895 +50762 Fbxo6 MGI:MGI:1354743|Ensembl:ENSMUSG00000055401|Vega:OTTMUSG00000010945 +50764 Fbxo15 MGI:MGI:1354755|Ensembl:ENSMUSG00000034391 +50765 Tfr2 MGI:MGI:1354956|Ensembl:ENSMUSG00000029716|Vega:OTTMUSG00000054540 +50766 Crim1 MGI:MGI:1354756|Ensembl:ENSMUSG00000024074 +50767 Pnpla6 MGI:MGI:1354723|Ensembl:ENSMUSG00000004565|Vega:OTTMUSG00000059166 +50768 Dlc1 MGI:MGI:1354949|Ensembl:ENSMUSG00000031523|Vega:OTTMUSG00000028535 +50769 Atp8a2 MGI:MGI:1354710|Ensembl:ENSMUSG00000021983|Vega:OTTMUSG00000032689 +50770 Atp11a MGI:MGI:1354735|Ensembl:ENSMUSG00000031441|Vega:OTTMUSG00000020604 +50771 Atp9b MGI:MGI:1354757|Ensembl:ENSMUSG00000024566 +50772 Mapk6 MGI:MGI:1354946|Ensembl:ENSMUSG00000042688|Vega:OTTMUSG00000037218 +50773 Nt5c MGI:MGI:1354954|Ensembl:ENSMUSG00000020736|Vega:OTTMUSG00000003441 +50774 Krtap5-1 MGI:MGI:1354732|Ensembl:ENSMUSG00000066100|Vega:OTTMUSG00000045002 +50775 Krtap5-4 MGI:MGI:1354758|Ensembl:ENSMUSG00000045236|Vega:OTTMUSG00000060152 +50776 Polg2 MGI:MGI:1354947|Ensembl:ENSMUSG00000020718|Vega:OTTMUSG00000003591 +50778 Rgs1 MGI:MGI:1354694|Ensembl:ENSMUSG00000026358|Vega:OTTMUSG00000035154 +50779 Rgs6 MGI:MGI:1354730|Ensembl:ENSMUSG00000021219|Vega:OTTMUSG00000029345 +50780 Rgs3 MGI:MGI:1354734|Ensembl:ENSMUSG00000059810|Vega:OTTMUSG00000000313 +50781 Dkk3 MGI:MGI:1354952|Ensembl:ENSMUSG00000030772|Vega:OTTMUSG00000060218 +50782 Rgs11 MGI:MGI:1354739|Ensembl:ENSMUSG00000024186|Vega:OTTMUSG00000026502 +50783 Lsm4 MGI:MGI:1354692|Ensembl:ENSMUSG00000031848|Vega:OTTMUSG00000029897 +50784 Plpp2 MGI:MGI:1354945|Ensembl:ENSMUSG00000052151|Vega:OTTMUSG00000035138 +50785 Hs6st1 MGI:MGI:1354958|Ensembl:ENSMUSG00000045216|Vega:OTTMUSG00000029555 +50786 Hs6st2 MGI:MGI:1354959|Ensembl:ENSMUSG00000062184|Vega:OTTMUSG00000017337 +50787 Hs6st3 MGI:MGI:1354960|Ensembl:ENSMUSG00000053465 +50788 Fbxl8 MGI:MGI:1354697|Ensembl:ENSMUSG00000033313|Vega:OTTMUSG00000027470 +50789 Fbxl3 MGI:MGI:1354702|Ensembl:ENSMUSG00000022124|Vega:OTTMUSG00000033217 +50790 Acsl4 MGI:MGI:1354713|Ensembl:ENSMUSG00000031278|Vega:OTTMUSG00000018811 +50791 Magi2 MGI:MGI:1354953|Ensembl:ENSMUSG00000040003|Vega:OTTMUSG00000025140 +50793 Orc3 MGI:MGI:1354944|Ensembl:ENSMUSG00000040044|Vega:OTTMUSG00000006352 +50794 Klf13 MGI:MGI:1354948|Ensembl:ENSMUSG00000052040|Vega:OTTMUSG00000044885 +50795 Sh3bgr MGI:MGI:1354740|Ensembl:ENSMUSG00000040666|Vega:OTTMUSG00000020060 +50796 Dmrt1 MGI:MGI:1354733|Ensembl:ENSMUSG00000024837|Vega:OTTMUSG00000034256 +50797 Copb2 MGI:MGI:1354962|Ensembl:ENSMUSG00000032458|Vega:OTTMUSG00000047583 +50798 Gne MGI:MGI:1354951|Ensembl:ENSMUSG00000028479|Vega:OTTMUSG00000007208 +50799 Slc25a13 MGI:MGI:1354721|Ensembl:ENSMUSG00000015112|Vega:OTTMUSG00000042278 +50800 Nr1h2-ps MGI:MGI:1354955 +50817 Capn15 MGI:MGI:1355075|Ensembl:ENSMUSG00000037326|Vega:OTTMUSG00000061845 +50849 Rnf10 MGI:MGI:1859162|Ensembl:ENSMUSG00000041740|Vega:OTTMUSG00000014638 +50850 Spast MGI:MGI:1858896|Ensembl:ENSMUSG00000024068 +50868 Keap1 MGI:MGI:1858732|Ensembl:ENSMUSG00000003308|Vega:OTTMUSG00000050608 +50873 Park2 MGI:MGI:1355296|Ensembl:ENSMUSG00000023826|Vega:OTTMUSG00000046340 +50874 Tmod4 MGI:MGI:1355285|Ensembl:ENSMUSG00000005628|Vega:OTTMUSG00000019672 +50875 Tmod3 MGI:MGI:1355315|Ensembl:ENSMUSG00000058587|Vega:OTTMUSG00000062847 +50876 Tmod2 MGI:MGI:1355335|Ensembl:ENSMUSG00000032186|Vega:OTTMUSG00000062853 +50877 Neu3 MGI:MGI:1355305|Ensembl:ENSMUSG00000035239|Vega:OTTMUSG00000059050 +50878 Stag3 MGI:MGI:1355311|Ensembl:ENSMUSG00000036928|Vega:OTTMUSG00000030509 +50880 Scly MGI:MGI:1355310|Ensembl:ENSMUSG00000026307|Vega:OTTMUSG00000022404 +50883 Chek2 MGI:MGI:1355321|Ensembl:ENSMUSG00000029521|Vega:OTTMUSG00000054224 +50884 Nckap1 MGI:MGI:1355333|Ensembl:ENSMUSG00000027002|Vega:OTTMUSG00000013373 +50887 Hmgn5 MGI:MGI:1355295|Ensembl:ENSMUSG00000031245|Vega:OTTMUSG00000018340 +50905 Il17rb MGI:MGI:1355292|Ensembl:ENSMUSG00000015966|Vega:OTTMUSG00000027818 +50907 Preb MGI:MGI:1355326|Ensembl:ENSMUSG00000045302|Vega:OTTMUSG00000022374 +50908 C1s1 MGI:MGI:1355312|Ensembl:ENSMUSG00000038521|Vega:OTTMUSG00000034941 +50909 C1ra MGI:MGI:1355313|Ensembl:ENSMUSG00000055172|Vega:OTTMUSG00000056669 +50911 Exosc9 MGI:MGI:1355319|Ensembl:ENSMUSG00000027714|Vega:OTTMUSG00000002113 +50912 Exosc10 MGI:MGI:1355322|Ensembl:ENSMUSG00000017264|Vega:OTTMUSG00000010937 +50913 Olig2 MGI:MGI:1355331|Ensembl:ENSMUSG00000039830|Vega:OTTMUSG00000019873 +50914 Olig1 MGI:MGI:1355334|Ensembl:ENSMUSG00000046160|Vega:OTTMUSG00000019872 +50915 Grb14 MGI:MGI:1355324|Ensembl:ENSMUSG00000026888|Vega:OTTMUSG00000012835 +50916 Irx4 MGI:MGI:1355275|Ensembl:ENSMUSG00000021604|Vega:OTTMUSG00000040088 +50917 Galns MGI:MGI:1355303|Ensembl:ENSMUSG00000015027|Vega:OTTMUSG00000061858 +50918 Myadm MGI:MGI:1355332|Ensembl:ENSMUSG00000068566|Vega:OTTMUSG00000057713 +50926 Hnrnpdl MGI:MGI:1355299|Ensembl:ENSMUSG00000029328|Vega:OTTMUSG00000024644 +50927 Nasp MGI:MGI:1355328|Ensembl:ENSMUSG00000028693|Vega:OTTMUSG00000009439 +50928 Klrg1 MGI:MGI:1355294|Ensembl:ENSMUSG00000030114|Vega:OTTMUSG00000026937 +50929 Il22 MGI:MGI:1355307|Ensembl:ENSMUSG00000074695|Vega:OTTMUSG00000042450 +50930 Tnfsf14 MGI:MGI:1355317|Ensembl:ENSMUSG00000005824 +50931 Il27ra MGI:MGI:1355318|Ensembl:ENSMUSG00000005465|Vega:OTTMUSG00000061191 +50932 Mink1 MGI:MGI:1355329|Ensembl:ENSMUSG00000020827|Vega:OTTMUSG00000006056 +50933 Uchl3 MGI:MGI:1355274|Ensembl:ENSMUSG00000022111 +50934 Slc7a8 MGI:MGI:1355323|Ensembl:ENSMUSG00000022180 +50935 St6galnac6 MGI:MGI:1355316|Ensembl:ENSMUSG00000026811|Vega:OTTMUSG00000011992 +50994 Mtag2 MGI:MGI:1860766|Ensembl:ENSMUSG00000091510 +50995 Uba2 MGI:MGI:1858313|Ensembl:ENSMUSG00000052997|Vega:OTTMUSG00000008405 +50996 Pdcd7 MGI:MGI:1859170|Ensembl:ENSMUSG00000041837|Vega:OTTMUSG00000062625 +50997 Mpp2 MGI:MGI:1858257|Ensembl:ENSMUSG00000017314|Vega:OTTMUSG00000002315 +51786 Cpsf2 MGI:MGI:1861601|Ensembl:ENSMUSG00000041781 +51788 H2afz MGI:MGI:1888388|Ensembl:ENSMUSG00000037894|Vega:OTTMUSG00000022256 +51789 Tnk2 MGI:MGI:1858308|Ensembl:ENSMUSG00000022791|Vega:OTTMUSG00000026940 +51791 Rgs14 MGI:MGI:1859709|Ensembl:ENSMUSG00000052087|Vega:OTTMUSG00000033508 +51792 Ppp2r1a MGI:MGI:1926334|Ensembl:ENSMUSG00000007564|Vega:OTTMUSG00000016281 +51793 Ddah2 MGI:MGI:1859016|Ensembl:ENSMUSG00000007039|Vega:OTTMUSG00000037923 +51795 Srpx MGI:MGI:1858306|Ensembl:ENSMUSG00000090084|Vega:OTTMUSG00000016900 +51796 Srrm1 MGI:MGI:1858303|Ensembl:ENSMUSG00000028809|Vega:OTTMUSG00000009683 +51797 Ctps MGI:MGI:1858304|Ensembl:ENSMUSG00000028633|Vega:OTTMUSG00000008810 +51798 Ech1 MGI:MGI:1858208|Ensembl:ENSMUSG00000053898|Vega:OTTMUSG00000031167 +51799 Rundc3a MGI:MGI:1858752|Ensembl:ENSMUSG00000006575|Vega:OTTMUSG00000002785 +51800 Bok MGI:MGI:1858494|Ensembl:ENSMUSG00000026278|Vega:OTTMUSG00000048660 +51801 Ramp1 MGI:MGI:1858418|Ensembl:ENSMUSG00000034353|Vega:OTTMUSG00000048487 +51810 Hnrnpu MGI:MGI:1858195|Ensembl:ENSMUSG00000039630|Vega:OTTMUSG00000021881 +51811 Clec4f MGI:MGI:1859834|Ensembl:ENSMUSG00000014542|Vega:OTTMUSG00000027021 +51812 Mcrs1 MGI:MGI:1858420|Ensembl:ENSMUSG00000037570 +51813 Ccnc MGI:MGI:1858199|Ensembl:ENSMUSG00000028252|Vega:OTTMUSG00000004717 +51818 D17Leh66E MGI:MGI:894609 +51819 D17Tu32 MGI:MGI:894610 +51820 D0Wfb1e MGI:MGI:1196622 +51821 D17Leh119 MGI:MGI:894608 +51822 D17Tu42 MGI:MGI:894611 +51823 D3Abb1e MGI:MGI:106226 +51825 D9Sut2e MGI:MGI:107993 +51827 D17Sut1e MGI:MGI:107963 +51828 D15Abb1e MGI:MGI:106320 +51829 D13Abb2e MGI:MGI:106337 +51830 D7Trk1e MGI:MGI:106450 +51831 D6Trk1e MGI:MGI:106465 +51832 D3Ggc1e MGI:MGI:106525 +51833 D2Uta1e MGI:MGI:107642 +51834 D2Ggc2e MGI:MGI:109426 +51835 D2Ggc3e MGI:MGI:1096316 +51836 DXGgc3e MGI:MGI:1096336 +51837 DXGgc5e MGI:MGI:1096352 +51838 D2Ggc5e MGI:MGI:1096354 +51839 D2Ggc4e MGI:MGI:1096357 +51840 D3Ggc3e MGI:MGI:1096378 +51842 D2Ertd93e MGI:MGI:1098685 +51843 D2Ertd48e MGI:MGI:1098704 +51845 D2Ertd63e MGI:MGI:1098781 +51847 D2Ertd92e MGI:MGI:1196245 +51848 D2Ggc6e MGI:MGI:1277104 +51849 D3Ggc4e MGI:MGI:1313273 +51850 DXSut1e MGI:MGI:107952 +51851 D9Sut1e MGI:MGI:107994 +51852 D5Sut1e MGI:MGI:107998 +51853 D4Sut1e MGI:MGI:107999 +51854 D3Sut1e MGI:MGI:108001 +51855 D1Sut1e MGI:MGI:108004 +51856 D8Sut1e MGI:MGI:109549 +51857 D2Sut1e MGI:MGI:99848 +51859 D19Ggc1e MGI:MGI:108455 +51860 D17Ggc2e MGI:MGI:108468 +51861 D6Sut1e MGI:MGI:109554 +51862 D2Bir27e MGI:MGI:1096333 +51863 D2Bir28e MGI:MGI:1096382 +51864 D2Ertd173e MGI:MGI:1098534 +51865 D2Ertd122e MGI:MGI:1098542 +51867 D2Ertd210e MGI:MGI:1098594 +51868 D2Ertd168e MGI:MGI:1098599 +51869 Rif1 MGI:MGI:1098622|Ensembl:ENSMUSG00000036202|Vega:OTTMUSG00000012437 +51870 D2Ertd112e MGI:MGI:1098688 +51872 D2Ertd282e MGI:MGI:1098728 +51873 D2Ertd127e MGI:MGI:1098745 +51875 Tmem141 MGI:MGI:1098773|Ensembl:ENSMUSG00000026939|Vega:OTTMUSG00000012514 +51877 D4Ertd290e MGI:MGI:1098810 +51878 D4Ertd298e MGI:MGI:1098813 +51879 D3Ertd425e MGI:MGI:1196233 +51880 D2Ertd239e MGI:MGI:1196239 +51883 D2Ertd259e MGI:MGI:1196285 +51885 Tubgcp4 MGI:MGI:1196293|Ensembl:ENSMUSG00000027263|Vega:OTTMUSG00000015965 +51886 Fubp1 MGI:MGI:1196294|Ensembl:ENSMUSG00000028034|Vega:OTTMUSG00000053719 +51887 D2Ertd397e MGI:MGI:1196321 +51889 D3Ertd343e MGI:MGI:1196346 +51891 D2Ertd468e MGI:MGI:1196366 +51893 D2Ertd198 MGI:MGI:1196374 +51896 D2Ertd357e MGI:MGI:1196407 +51897 Atg13 MGI:MGI:1196429|Ensembl:ENSMUSG00000027244|Vega:OTTMUSG00000014308 +51898 D3Ertd452e MGI:MGI:1196447 +51900 D2Ertd329e MGI:MGI:1196461 +51901 D2Ertd295e MGI:MGI:1202707 +51902 Rnf24 MGI:MGI:1261771|Ensembl:ENSMUSG00000048911|Vega:OTTMUSG00000016039 +51903 D2Ertd554e MGI:MGI:1261790 +51904 D3Ertd508e MGI:MGI:1261795 +51907 D3Ertd547e MGI:MGI:1261830 +51908 D3Ertd568e MGI:MGI:1261853 +51909 D3Ertd491e MGI:MGI:1261861 +51914 D3Ertd108e MGI:MGI:1261903 +51915 D3Ertd211e MGI:MGI:1261917 +51917 D2Ertd691e MGI:MGI:1277145 +51919 D2Ertd634e MGI:MGI:1277188 +51920 D2Ertd616e MGI:MGI:1277192 +51922 D2Ertd612e MGI:MGI:1277205 +51925 D2Ertd640e MGI:MGI:1277224 +51926 D2Ertd623e MGI:MGI:1277232 +51927 D3Ertd711e MGI:MGI:1289170 +51928 D1Ertd692 MGI:MGI:1289177 +51929 D1Ertd704e MGI:MGI:1289186 +51931 D1Ertd799e MGI:MGI:1289199 +51936 D3Ertd740e MGI:MGI:1289243 +51937 D3Ertd797e MGI:MGI:1289260 +51938 Ccdc39 MGI:MGI:1289263|Ensembl:ENSMUSG00000027676|Vega:OTTMUSG00000026483 +51939 D3Ertd731e MGI:MGI:1289264 +51940 D1Ertd705e MGI:MGI:1289270 +51944 Knstrn MGI:MGI:1289298|Ensembl:ENSMUSG00000027331|Vega:OTTMUSG00000015640 +51945 D1Ertd811e MGI:MGI:1289303 +51949 D19Bir8e MGI:MGI:1096334 +51951 D17Ertd96e MGI:MGI:1098714 +51952 D17Ertd29e MGI:MGI:1098774 +51953 D19Ertd79e MGI:MGI:1098777 +51956 D13Sut1e MGI:MGI:107975 +51957 D12Sut1e MGI:MGI:107987 +51959 D7Ertd1e MGI:MGI:1098762 +51960 Kctd18 MGI:MGI:3603813|Ensembl:ENSMUSG00000054770|Vega:OTTMUSG00000035129 +51963 D6Ggc1e MGI:MGI:106466 +51966 D11Bhm181e MGI:MGI:106813 +51971 D8Ggc2e MGI:MGI:108514 +51973 DXGgc1e MGI:MGI:106243 +51974 D8Ggc1e MGI:MGI:106424 +51975 D4Ggc2e MGI:MGI:106508 +51976 D1Ggc1e MGI:MGI:106574 +51977 D4Ggc3e MGI:MGI:107331 +51978 D2Ggc1e MGI:MGI:107354 +51979 DXGgc2e MGI:MGI:108453 +51980 D6Ggc2e MGI:MGI:108545 +51981 D5Ggc1e MGI:MGI:108552 +51982 D1Ggc3e MGI:MGI:108573 +51983 D1Ggc2e MGI:MGI:108574 +51984 D4Ggc4e MGI:MGI:109421 +51985 D3Ggc2e MGI:MGI:109423 +51986 D14Sut1e MGI:MGI:109537 +51987 D12Sut2e MGI:MGI:109539 +51988 D8Ggc3e MGI:MGI:1096326 +51990 D9Ertd12e MGI:MGI:1098544 +51991 D8Ertd67e MGI:MGI:1098545 +51995 D19Ertd200e MGI:MGI:1098620 +51996 D8Ertd51e MGI:MGI:1098636 +51997 D17Ertd165e MGI:MGI:1098646 +51998 D17Ertd191e MGI:MGI:1098652 +51999 D17Ertd262e MGI:MGI:1098711 +52000 D17Ertd277e MGI:MGI:1098719 +52002 D6Ertd15e MGI:MGI:1098763 +52003 DXErtd11e MGI:MGI:1098764 +52004 Cdk2ap2 MGI:MGI:1098779|Ensembl:ENSMUSG00000024856|Vega:OTTMUSG00000037016 +52006 D7Ertd59e MGI:MGI:1098831 +52009 Hn1l MGI:MGI:1196260|Ensembl:ENSMUSG00000024165 +52011 D19Ertd132e MGI:MGI:1196276 +52013 R3hcc1l MGI:MGI:1196316|Ensembl:ENSMUSG00000025184|Vega:OTTMUSG00000035132 +52014 Nus1 MGI:MGI:1196365|Ensembl:ENSMUSG00000023068 +52015 D10Ertd276e MGI:MGI:1196420 +52016 D19Ertd409e MGI:MGI:1196424 +52018 D13Ertd570e MGI:MGI:1261769 +52019 D17Ertd589e MGI:MGI:1261784 +52020 Umodl1 MGI:MGI:1929785|Ensembl:ENSMUSG00000054134 +52023 Pibf1 MGI:MGI:1261910|Ensembl:ENSMUSG00000022064 +52024 Ankrd22 MGI:MGI:1277101|Ensembl:ENSMUSG00000024774|Vega:OTTMUSG00000034904 +52027 D17Ertd648e MGI:MGI:1277213 +52028 Bbs1 MGI:MGI:1277215|Ensembl:ENSMUSG00000006464 +52029 D17Ertd657e MGI:MGI:1277219 +52033 Pbk MGI:MGI:1289156|Ensembl:ENSMUSG00000022033|Vega:OTTMUSG00000027681 +52034 D19Ertd756e MGI:MGI:1289166 +52036 Ppp6r3 MGI:MGI:1921807|Ensembl:ENSMUSG00000024908 +52037 D17Ertd763e MGI:MGI:1289249 +52038 D10Ertd755e MGI:MGI:1289253 +52040 Ppp1r10 MGI:MGI:1289273|Ensembl:ENSMUSG00000039220|Vega:OTTMUSG00000021047 +52044 D19Ertd744e MGI:MGI:1289330 +52046 DXGgc6e MGI:MGI:1096322 +52047 D8Ggc4e MGI:MGI:1096323 +52048 D6Ggc3e MGI:MGI:1096332 +52049 D1Ggc4e MGI:MGI:1096346 +52050 DXGgc4e MGI:MGI:1096395 +52053 D1Ertd86e MGI:MGI:1098581 +52054 D4Ertd58e MGI:MGI:1098582 +52055 Rab11fip5 MGI:MGI:1098586|Ensembl:ENSMUSG00000051343|Vega:OTTMUSG00000057879 +52056 D1Ertd62e MGI:MGI:1098587 +52058 D4Ertd76e MGI:MGI:1098617 +52061 D3Ertd34e MGI:MGI:1098625 +52062 D9Ertd26e MGI:MGI:1098634 +52064 Coq5 MGI:MGI:1098643|Ensembl:ENSMUSG00000041733|Vega:OTTMUSG00000014644 +52065 Mfhas1 MGI:MGI:1098644|Ensembl:ENSMUSG00000070056|Vega:OTTMUSG00000029932 +52066 D1Ertd57e MGI:MGI:1098656 +52067 D8Ertd56e MGI:MGI:1098661 +52068 D4Ertd78e MGI:MGI:1098668 +52070 D4Ertd31e MGI:MGI:1098679 +52071 D8Ertd54e MGI:MGI:1098681 +52072 D5Ertd77e MGI:MGI:1098698 +52074 D6Ertd47e MGI:MGI:1098706 +52076 Tmem38b MGI:MGI:1098718|Ensembl:ENSMUSG00000028420|Vega:OTTMUSG00000007005 +52078 D6Ertd87e MGI:MGI:1098737 +52079 D1Ertd83e MGI:MGI:1098750 +52080 D6Ertd90e MGI:MGI:1098758 +52082 D7Ertd74e MGI:MGI:1098778 +52086 D1Ertd84e MGI:MGI:1098800 +52093 D6Ggc4e MGI:MGI:1313287 +52094 D8Ggc5e MGI:MGI:1313292 +52095 D5H4S181E MGI:MGI:99697 +52097 D16Ertd6e MGI:MGI:1098589 +52099 D1Ertd75e MGI:MGI:1098655 +52100 D11Ertd4e MGI:MGI:1098792 +52103 D11Ggc1e MGI:MGI:106359 +52104 D16Ggc1e MGI:MGI:109387 +52105 D1Ertd164e MGI:MGI:1098546 +52107 D8Ertd130e MGI:MGI:1098609 +52108 D9Ertd115e MGI:MGI:1098616 +52116 D8Ertd317e MGI:MGI:1196257 +52118 Pvr MGI:MGI:107741|Ensembl:ENSMUSG00000040511|Vega:OTTMUSG00000031524 +52120 Hgsnat MGI:MGI:1196297|Ensembl:ENSMUSG00000037260|Vega:OTTMUSG00000060876 +52123 Agpat5 MGI:MGI:1196345|Ensembl:ENSMUSG00000031467|Vega:OTTMUSG00000030978 +52124 D6Ertd439e MGI:MGI:1196379 +52132 Ccdc97 MGI:MGI:1196455|Ensembl:ENSMUSG00000002608|Vega:OTTMUSG00000022296 +52134 D4Ertd510e MGI:MGI:1261832 +52137 D7Ertd595e MGI:MGI:1261862 +52138 D5Ertd543e MGI:MGI:1261881 +52139 D5Ertd560e MGI:MGI:1261883 +52140 D4Ertd582e MGI:MGI:1261909 +52141 D6Ertd588e MGI:MGI:1261911 +52144 D7Ertd661e MGI:MGI:1277190 +52145 D9Ertd720e MGI:MGI:1289150 +52149 DXErtd770e MGI:MGI:1289339 +52150 Kcnk6 MGI:MGI:1891291|Ensembl:ENSMUSG00000046410|Vega:OTTMUSG00000059215 +52151 D14Bur1e MGI:MGI:1346034 +52153 D11Jkn1e MGI:MGI:88969 +52154 D11Ggc2e MGI:MGI:106358 +52155 D18Ggc1e MGI:MGI:107221 +52156 D17Ggc1e MGI:MGI:107229 +52157 D10Ggc1e MGI:MGI:108508 +52158 D18Ggc2e MGI:MGI:109385 +52159 D15Ggc1e MGI:MGI:109389 +52160 D15Ggc2e MGI:MGI:109535 +52161 D7Bir19e MGI:MGI:1096348 +52162 D7Bir18e MGI:MGI:1096390 +52163 Camk1 MGI:MGI:1098535|Ensembl:ENSMUSG00000030272|Vega:OTTMUSG00000022452 +52164 D4Ertd117e MGI:MGI:1098536 +52165 D2Ertd105e MGI:MGI:1098538 +52166 D3Ertd302e MGI:MGI:1098540 +52167 D8Ertd294e MGI:MGI:1098543 +52168 D7Ertd193e MGI:MGI:1098548 +52169 D1Ertd182e MGI:MGI:1098557 +52172 D4Ertd264e MGI:MGI:1098560 +52173 D9Ertd133e MGI:MGI:1098561 +52174 Tmem222 MGI:MGI:1098568|Ensembl:ENSMUSG00000028857|Vega:OTTMUSG00000011154 +52175 DXErtd242e MGI:MGI:1098571 +52176 D8Ertd124e MGI:MGI:1098573 +52177 D4Ertd151e MGI:MGI:1098579 +52179 D9Ertd256e MGI:MGI:1098585 +52181 D5Ertd163e MGI:MGI:1098593 +52182 D1Ertd148e MGI:MGI:1098596 +52183 D5Ertd255e MGI:MGI:1098598 +52184 Odf2l MGI:MGI:1098600|Ensembl:ENSMUSG00000028256|Vega:OTTMUSG00000055187 +52186 D8Ertd158e MGI:MGI:1098603 +52187 Rragd MGI:MGI:1098604|Ensembl:ENSMUSG00000028278|Vega:OTTMUSG00000004997 +52189 D1Ertd228e MGI:MGI:1098608 +52190 D3Ertd258e MGI:MGI:1098611 +52193 D15Ertd50e MGI:MGI:1098630 +52194 D5Ertd102e MGI:MGI:1098631 +52195 D8Ertd252e MGI:MGI:1098632 +52196 D7Ertd187e MGI:MGI:1098637 +52197 DXErtd223e MGI:MGI:1098639 +52198 D3Ertd270e MGI:MGI:1098640 +52199 D8Ertd107e MGI:MGI:1098645 +52201 D1Ertd273e MGI:MGI:1098650 +52202 Rbm34 MGI:MGI:1098653|Ensembl:ENSMUSG00000033931|Vega:OTTMUSG00000061629 +52203 D9Ertd306e MGI:MGI:1098654 +52204 D6Ertd234e MGI:MGI:1098662 +52205 D4Ertd179e MGI:MGI:1098664 +52206 Anapc4 MGI:MGI:1098673|Ensembl:ENSMUSG00000029176|Vega:OTTMUSG00000023353 +52207 D1Ertd309e MGI:MGI:1098677 +52208 D9Ertd292e MGI:MGI:1098683 +52211 D3Ertd246e MGI:MGI:1098692 +52212 D9Ertd167e MGI:MGI:1098695 +52213 D4Ertd100e MGI:MGI:1098696 +52222 D7Ertd128e MGI:MGI:1098716 +52223 D6Ertd160e MGI:MGI:1098724 +52224 D5Ertd215e MGI:MGI:1098730 +52225 D4Ertd103e MGI:MGI:1098731 +52228 D1Ertd230e MGI:MGI:1098738 +52230 D5Ertd121e MGI:MGI:1098740 +52231 Ankzf1 MGI:MGI:1098746|Ensembl:ENSMUSG00000026199|Vega:OTTMUSG00000021565 +52232 D3Ertd207e MGI:MGI:1098751 +52234 D7Ertd183e MGI:MGI:1098756 +52235 D9Ertd305e MGI:MGI:1098760 +52238 D15Ertd30e MGI:MGI:1098771 +52243 D3Ertd229e MGI:MGI:1098803 +52244 D5Ertd159e MGI:MGI:1098805 +52245 Commd2 MGI:MGI:1098806|Ensembl:ENSMUSG00000036513|Vega:OTTMUSG00000029283 +52246 D1Ertd291e MGI:MGI:1098811 +52247 D5Ertd236e MGI:MGI:1098814 +52249 D5Ertd301e MGI:MGI:1098822 +52250 Reep1 MGI:MGI:1098827|Ensembl:ENSMUSG00000052852|Vega:OTTMUSG00000029707 +52252 D3Ertd162e MGI:MGI:1098833 +52259 D9Ertd334e MGI:MGI:1196229 +52260 D4Ertd279e MGI:MGI:1196231 +52261 D8Ertd268e MGI:MGI:1196232 +52262 D7Ertd312e MGI:MGI:1196236 +52263 D1Ertd475e MGI:MGI:1196240 +52268 D5Ertd422e MGI:MGI:1196253 +52274 D8Ertd381e MGI:MGI:1196272 +52275 D7Ertd316e MGI:MGI:1196273 +52276 Cdca8 MGI:MGI:1196274|Ensembl:ENSMUSG00000028873|Vega:OTTMUSG00000009201 +52278 D1Ertd185e MGI:MGI:1196303 +52281 D9Ertd382e MGI:MGI:1196307 +52282 D9Ertd356e MGI:MGI:1196309 +52285 D6Ertd474e MGI:MGI:1196315 +52292 D5Ertd470e MGI:MGI:1196347 +52293 D7Ertd351e MGI:MGI:1196349 +52296 D1Ertd399e MGI:MGI:1196358 +52297 D5Ertd440e MGI:MGI:1196367 +52298 D8Ertd323e MGI:MGI:1196369 +52299 D9Ertd338e MGI:MGI:1196376 +52302 D4Ertd335e MGI:MGI:1196385 +52303 D1Ertd218e MGI:MGI:1196387 +52305 D1Ertd259e MGI:MGI:1196397 +52307 D9Ertd241e MGI:MGI:1196404 +52308 D4Ertd361e MGI:MGI:1196408 +52310 D7Ertd344e MGI:MGI:1196417 +52312 D9Ertd341e MGI:MGI:1196421 +52316 D6Ertd318e MGI:MGI:1196432 +52317 D7Ertd388e MGI:MGI:1196434 +52318 D1Ertd448e MGI:MGI:1196435 +52320 D6Ertd469e MGI:MGI:1196443 +52323 Klhl7 MGI:MGI:1196453|Ensembl:ENSMUSG00000028986|Vega:OTTMUSG00000053534 +52325 D7Ertd413e MGI:MGI:1196462 +52326 D1Ertd408e MGI:MGI:1196465 +52331 Stbd1 MGI:MGI:1261768|Ensembl:ENSMUSG00000047963|Vega:OTTMUSG00000055606 +52333 D7Ertd523e MGI:MGI:1261773 +52334 D7Ertd481e MGI:MGI:1261786 +52335 Atxn1l MGI:MGI:3694797|Ensembl:ENSMUSG00000069895|Vega:OTTMUSG00000061923 +52336 D5Ertd525e MGI:MGI:1261798 +52338 D8Ertd563e MGI:MGI:1261801 +52339 D8Ertd572e MGI:MGI:1261803 +52340 D4Ertd513e MGI:MGI:1261807 +52341 D4Ertd571e MGI:MGI:1261808 +52343 D6Ertd490e MGI:MGI:1261817 +52344 D4Ertd199e MGI:MGI:1261818 +52346 D2Ertd501e MGI:MGI:1261829 +52347 D1Ertd564e MGI:MGI:1261833 +52348 Vps37a MGI:MGI:1261835|Ensembl:ENSMUSG00000031600 +52349 D7Ertd526e MGI:MGI:1261843 +52350 D5Ertd521e MGI:MGI:1261844 +52355 DXErtd573e MGI:MGI:1261865 +52356 D1Ertd507e MGI:MGI:1261866 +52357 Wwc2 MGI:MGI:1261872|Ensembl:ENSMUSG00000031563|Vega:OTTMUSG00000061832 +52358 D1Ertd576e MGI:MGI:1261876 +52359 D7Ertd495e MGI:MGI:1261879 +52360 D8Ertd362e MGI:MGI:1261880 +52361 D9Ertd496e MGI:MGI:1261886 +52363 D9Ertd596e MGI:MGI:1261891 +52365 D7Ertd558e MGI:MGI:1261895 +52366 D8Ertd503e MGI:MGI:1261896 +52367 D8Ertd575e MGI:MGI:1261904 +52370 D6Ertd456e MGI:MGI:1261916 +52372 D6Ertd527e MGI:MGI:1261919|Ensembl:ENSMUSG00000090891|Vega:OTTMUSG00000057135 +52377 Rcn3 MGI:MGI:1277122|Ensembl:ENSMUSG00000019539|Vega:OTTMUSG00000031713 +52379 D4Ertd669e MGI:MGI:1277129 +52381 D5Ertd566e MGI:MGI:1277135 +52382 D8Ertd674e MGI:MGI:1277136 +52383 D1Ertd646e MGI:MGI:1277140 +52386 D1Ertd702e MGI:MGI:1277156 +52387 D5Ertd700e MGI:MGI:1277158 +52389 Adgra1 MGI:MGI:1277167|Ensembl:ENSMUSG00000025475|Vega:OTTMUSG00000023085 +52392 D1Ertd622e MGI:MGI:1277184|Ensembl:ENSMUSG00000044768|Vega:OTTMUSG00000021769 +52393 D7Ertd677e MGI:MGI:1277189 +52397 Zfp644 MGI:MGI:1277212|Ensembl:ENSMUSG00000049606|Vega:OTTMUSG00000023248 +52398 Sept11 MGI:MGI:1277214|Ensembl:ENSMUSG00000058013|Vega:OTTMUSG00000055620 +52399 D7Ertd685e MGI:MGI:1277217 +52400 D7Ertd602e MGI:MGI:1277230 +52401 D5Ertd615e MGI:MGI:1277236|Ensembl:ENSMUSG00000029092 +52403 D4Ertd628e MGI:MGI:1277243 +52408 D7Ertd807e MGI:MGI:1289158 +52409 D5Ertd798e MGI:MGI:1289173 +52410 D8Ertd769e MGI:MGI:1289179 +52412 D9Ertd788e MGI:MGI:1289185 +52414 D2Ertd742e MGI:MGI:1289191 +52415 D4Ertd639e MGI:MGI:1289195 +52419 D7Ertd783e MGI:MGI:1289206 +52421 D4Ertd681e MGI:MGI:1289211 +52423 D8Ertd620e MGI:MGI:1289220 +52427 D4Ertd111e MGI:MGI:1289233 +52428 Rhpn2 MGI:MGI:1289234|Ensembl:ENSMUSG00000030494|Vega:OTTMUSG00000024889 +52430 Echdc2 MGI:MGI:1289238|Ensembl:ENSMUSG00000028601|Vega:OTTMUSG00000009483 +52431 D9Ertd815e MGI:MGI:1289240 +52432 Ppp2r2d MGI:MGI:1289252|Ensembl:ENSMUSG00000041769|Vega:OTTMUSG00000029360 +52433 D2Ertd337e MGI:MGI:1289254 +52440 Tax1bp1 MGI:MGI:1289308|Ensembl:ENSMUSG00000004535|Vega:OTTMUSG00000022785 +52443 Mrpl48 MGI:MGI:1289321|Ensembl:ENSMUSG00000030706|Vega:OTTMUSG00000025231 +52444 D4Ertd804e MGI:MGI:1289322 +52448 D14Rp4e MGI:MGI:90164 +52449 D11Ggc3e MGI:MGI:1096328 +52450 D10Ggc2e MGI:MGI:1096371 +52451 D15Ggc3e MGI:MGI:1096374 +52452 D16Ggc2e MGI:MGI:1096394 +52453 D14Ertd24e MGI:MGI:1098537 +52455 D11Ertd49e MGI:MGI:1098572 +52458 D15Ertd55e MGI:MGI:1098605 +52461 D13Ertd94e MGI:MGI:1098676 +52462 D10Ertd43e MGI:MGI:1098690 +52463 Tet1 MGI:MGI:1098693|Ensembl:ENSMUSG00000047146|Vega:OTTMUSG00000037102 +52464 D16Ertd88e MGI:MGI:1098721 +52466 Slc46a1 MGI:MGI:1098733|Ensembl:ENSMUSG00000020829|Vega:OTTMUSG00000000134 +52467 D11Ertd72e MGI:MGI:1098736 +52468 Ctdsp2 MGI:MGI:1098748|Ensembl:ENSMUSG00000078429 +52469 Coa3 MGI:MGI:1098757|Ensembl:ENSMUSG00000017188|Vega:OTTMUSG00000002762 +52471 D13Ertd37e MGI:MGI:1098794 +52473 D11Ertd80e MGI:MGI:1098812 +52474 D14Ertd16e MGI:MGI:1098821 +52475 D13Ertd42e MGI:MGI:1098830 +52477 Angel2 MGI:MGI:1196310|Ensembl:ENSMUSG00000026634|Vega:OTTMUSG00000021514 +52478 D6Ertd131e MGI:MGI:1196433 +52480 Snhg14 MGI:MGI:1289201|Ensembl:ENSMUSG00000100826 +52481 D7Ertd758e MGI:MGI:1289235 +52482 D10Ggc3e MGI:MGI:1289259 +52483 D0Wsu1e MGI:MGI:101945 +52485 D5Ertd505e MGI:MGI:1261842 +52486 D19Rp19e MGI:MGI:91337 +52487 D7Arn1e MGI:MGI:1095741 +52490 D18Ertd289e MGI:MGI:1098595 +52492 D18Ertd232e MGI:MGI:1098635 +52493 D14Ertd170e MGI:MGI:1098666 +52494 D12Ertd129e MGI:MGI:1098671 +52495 D12Ertd208e MGI:MGI:1098678 +52496 D15Ertd136e MGI:MGI:1098705 +52498 D15Ertd180e MGI:MGI:1098753 +52502 Carhsp1 MGI:MGI:1196368|Ensembl:ENSMUSG00000008393 +52504 Cenpo MGI:MGI:1923800|Ensembl:ENSMUSG00000020652|Vega:OTTMUSG00000033102 +52505 D13Ertd463e MGI:MGI:1196446 +52508 D14Ertd574e MGI:MGI:1261823 +52510 D15Ertd529e MGI:MGI:1261888 +52511 D18Ertd201e MGI:MGI:1261897 +52512 D14Ertd670e MGI:MGI:1277153 +52513 Ddx56 MGI:MGI:1277172|Ensembl:ENSMUSG00000004393|Vega:OTTMUSG00000000779 +52519 D18Ertd693e MGI:MGI:1289261 +52521 Zfp622 MGI:MGI:1289282|Ensembl:ENSMUSG00000052253 +52524 D14Ertd725e MGI:MGI:1289327 +52525 D16Ertd780e MGI:MGI:1289328 +52526 D6Mm3e MGI:MGI:1315193 +52527 D6Mm4e MGI:MGI:1315212 +52528 D17Rp11e MGI:MGI:90952 +52530 Nhp2 MGI:MGI:1098547|Ensembl:ENSMUSG00000001056|Vega:OTTMUSG00000005610 +52531 D13Ertd224e MGI:MGI:1098552 +52532 D12Ertd123e MGI:MGI:1098569 +52534 D10Ertd140e MGI:MGI:1098575 +52535 Mettl17 MGI:MGI:1098577|Ensembl:ENSMUSG00000004561|Vega:OTTMUSG00000036453 +52536 D13Ertd219e MGI:MGI:1098591 +52537 D18Ertd155e MGI:MGI:1098621 +52538 Acaa2 MGI:MGI:1098623|Ensembl:ENSMUSG00000036880 +52540 D13Ertd104e MGI:MGI:1098638 +52542 D15Ertd154e MGI:MGI:1098657 +52543 D18Ertd169e MGI:MGI:1098663 +52544 D15Ertd181e MGI:MGI:1098665 +52545 D12Ertd216e MGI:MGI:1098674 +52546 D12Ertd247e MGI:MGI:1098680 +52548 D13Ertd150e MGI:MGI:1098689 +52549 D13Ertd212e MGI:MGI:1098691 +52550 D15Ertd271e MGI:MGI:1098694 +52551 Sgta MGI:MGI:1098703|Ensembl:ENSMUSG00000004937 +52552 Parp8 MGI:MGI:1098713|Ensembl:ENSMUSG00000021725 +52554 D11Ertd134e MGI:MGI:1098725 +52558 D10Ertd284e MGI:MGI:1098747 +52559 D15Ertd244e MGI:MGI:1098759 +52561 D13Ertd205e MGI:MGI:1098786 +52563 Cdc23 MGI:MGI:1098815|Ensembl:ENSMUSG00000024370|Vega:OTTMUSG00000033488 +52564 D10Ertd126e MGI:MGI:1098819 +52565 D12Ertd125e MGI:MGI:1098825 +52566 D11Ertd142e MGI:MGI:1098828 +52570 Ccdc69 MGI:MGI:1196234|Ensembl:ENSMUSG00000049588|Vega:OTTMUSG00000005680 +52572 D11Ertd379e MGI:MGI:1196247 +52574 D11Ertd326e MGI:MGI:1196254 +52575 Trmt10c MGI:MGI:1196261|Ensembl:ENSMUSG00000044763|Vega:OTTMUSG00000025839 +52576 D13Ertd376e MGI:MGI:1196278 +52583 D15Ertd320e MGI:MGI:1196308 +52585 Dhrs1 MGI:MGI:1196314|Ensembl:ENSMUSG00000002332|Vega:OTTMUSG00000027853 +52586 D13Ertd311e MGI:MGI:1196318 +52587 D13Ertd476e MGI:MGI:1196322 +52588 Tspan14 MGI:MGI:1196325|Ensembl:ENSMUSG00000037824 +52589 Ncald MGI:MGI:1196326|Ensembl:ENSMUSG00000051359|Vega:OTTMUSG00000028025 +52590 D13Ertd297e MGI:MGI:1196327 +52592 Brms1l MGI:MGI:1196337|Ensembl:ENSMUSG00000012076 +52593 D18Ertd390e MGI:MGI:1196372 +52594 D11Ertd437e MGI:MGI:1196382 +52595 D15Ertd430e MGI:MGI:1196383 +52604 D13Ertd324e MGI:MGI:1196411 +52607 D10Ertd447e MGI:MGI:1196430 +52609 Cbx7 MGI:MGI:1196439|Ensembl:ENSMUSG00000053411|Vega:OTTMUSG00000017275 +52612 D13Ertd332e MGI:MGI:1196451 +52614 Adgre4 MGI:MGI:1196464|Ensembl:ENSMUSG00000032915 +52615 Suz12 MGI:MGI:1261758|Ensembl:ENSMUSG00000017548|Vega:OTTMUSG00000000192 +52616 D14Ertd426e MGI:MGI:1261763 +52617 D16Ertd550e MGI:MGI:1261765 +52622 D15Ertd556e MGI:MGI:1261789 +52625 D16Ertd534e MGI:MGI:1261796 +52626 Cdkn2aipnl MGI:MGI:1261797|Ensembl:ENSMUSG00000020392|Vega:OTTMUSG00000005612 +52627 D11Ertd546e MGI:MGI:1261799 +52629 D11Ertd518e MGI:MGI:1261812 +52632 D11Ertd540e MGI:MGI:1261825 +52633 Nit2 MGI:MGI:1261838|Ensembl:ENSMUSG00000022751 +52634 D11Ertd506e MGI:MGI:1261840 +52635 Esyt2 MGI:MGI:1261845|Ensembl:ENSMUSG00000021171 +52637 Cisd1 MGI:MGI:1261855|Ensembl:ENSMUSG00000037710|Vega:OTTMUSG00000031045 +52638 D10Ertd494e MGI:MGI:1261857 +52639 Wipi1 MGI:MGI:1261864|Ensembl:ENSMUSG00000041895|Vega:OTTMUSG00000003347 +52643 D18Ertd511e MGI:MGI:1261875 +52645 D16Ertd519e MGI:MGI:1261885 +52647 D15Ertd509e MGI:MGI:1261893 +52648 D10Ertd533e MGI:MGI:1261894 +52649 D15Ertd489e MGI:MGI:1261905 +52650 D15Ertd492e MGI:MGI:1261907 +52653 Nudcd2 MGI:MGI:1277103|Ensembl:ENSMUSG00000020328|Vega:OTTMUSG00000005435 +52658 D10Ertd638e MGI:MGI:1277127 +52661 D18Ertd613e MGI:MGI:1277138 +52662 Ldlrad4 MGI:MGI:1277150|Ensembl:ENSMUSG00000024544 +52665 Echdc1 MGI:MGI:1277169|Ensembl:ENSMUSG00000019883|Vega:OTTMUSG00000028057 +52666 Arhgef25 MGI:MGI:1277173|Ensembl:ENSMUSG00000019467 +52668 Ifi27 MGI:MGI:1277180|Ensembl:ENSMUSG00000064215|Vega:OTTMUSG00000021960 +52669 D14Ertd611e MGI:MGI:1277181 +52670 Cpsf4l MGI:MGI:1277182|Ensembl:ENSMUSG00000018727|Vega:OTTMUSG00000003849 +52673 D13Ertd608e MGI:MGI:1277199 +52676 D18Ertd665e MGI:MGI:1277235 +52677 D12Ertd673e MGI:MGI:1277237 +52679 E2f7 MGI:MGI:1289147|Ensembl:ENSMUSG00000020185|Vega:OTTMUSG00000037938 +52680 D13Ertd787e MGI:MGI:1289159 +52682 D11Ertd726e MGI:MGI:1289163 +52683 Ncaph2 MGI:MGI:1289164|Ensembl:ENSMUSG00000008690|Vega:OTTMUSG00000024517 +52685 Cd300lg MGI:MGI:1289168|Ensembl:ENSMUSG00000017309|Vega:OTTMUSG00000002316 +52686 Mettl2 MGI:MGI:1289171|Ensembl:ENSMUSG00000020691|Vega:OTTMUSG00000002832 +52688 D16Ertd779e MGI:MGI:1289178 +52690 Setd3 MGI:MGI:1289184|Ensembl:ENSMUSG00000056770|Vega:OTTMUSG00000019487 +52692 D16Ertd803e MGI:MGI:1289203 +52695 D13Ertd666e MGI:MGI:1289223 +52696 Zwint MGI:MGI:1289227|Ensembl:ENSMUSG00000019923|Vega:OTTMUSG00000028989 +52700 Txndc17 MGI:MGI:1289248|Ensembl:ENSMUSG00000020803|Vega:OTTMUSG00000006101 +52701 D10Ertd709e MGI:MGI:1289255 +52702 D11Ertd712e MGI:MGI:1289262 +52704 D11Ertd717e MGI:MGI:1289268 +52705 Krr1 MGI:MGI:1289274|Ensembl:ENSMUSG00000063334|Vega:OTTMUSG00000027781 +52706 D10Ertd761e MGI:MGI:1289277 +52708 Zfp410 MGI:MGI:1289280|Ensembl:ENSMUSG00000042472 +52710 Slc52a2 MGI:MGI:1289288|Ensembl:ENSMUSG00000022560 +52711 D11Ertd729e MGI:MGI:1289291 +52712 Zkscan6 MGI:MGI:1289293|Ensembl:ENSMUSG00000018347|Vega:OTTMUSG00000005906 +52713 Ccdc59 MGI:MGI:1289302|Ensembl:ENSMUSG00000019897|Vega:OTTMUSG00000032766 +52714 D16Ertd778e MGI:MGI:1289305 +52715 Ccdc43 MGI:MGI:1289318|Ensembl:ENSMUSG00000020925|Vega:OTTMUSG00000002964 +52716 D13Ertd776e MGI:MGI:1289320 +52717 Anapc16 MGI:MGI:1289325|Ensembl:ENSMUSG00000020107|Vega:OTTMUSG00000043347 +52721 D18Ertd734e MGI:MGI:1289338 +52722 D14Ertd723e MGI:MGI:1331640 +52723 D14Ertd528e MGI:MGI:1331641 +52724 D14Ertd275e MGI:MGI:1331642 +52726 D17Zt8e MGI:MGI:108147 +52728 D17Zt10e MGI:MGI:108149 +52729 D17Zt11e MGI:MGI:108150 +52730 D17Zt12e MGI:MGI:108151 +52731 D2Wsu39e MGI:MGI:106546 +52732 D2Wsu34e MGI:MGI:106547 +52733 D2Wsu32e MGI:MGI:106548 +52734 D13Uth9e MGI:MGI:108483 +52735 D13Uth8e MGI:MGI:108484 +52736 D13Uth7e MGI:MGI:108485 +52737 D13Uth6e MGI:MGI:108486 +52738 D19Cct1e MGI:MGI:1098797 +52739 D7Wsu1e MGI:MGI:94222 +52740 D1Wsu1e MGI:MGI:91861 +52741 D6Wsu1e MGI:MGI:93831 +52742 D9Wsu1e MGI:MGI:94855 +52743 D17Wsu1e MGI:MGI:90998 +52744 D7Wsu41e MGI:MGI:106445 +52745 D4Wsu36e MGI:MGI:106500 +52746 D4Wsu35e MGI:MGI:106501 +52747 D4Wsu29e MGI:MGI:106503 +52748 D19Wsu195e MGI:MGI:1099797 +52749 D17Wsu196e MGI:MGI:1099798 +52750 D17Wsu193e MGI:MGI:1099812 +52751 D15Wsu192e MGI:MGI:1099837 +52753 D12Wsu1e MGI:MGI:89583 +52754 D13Wsu1e MGI:MGI:89885 +52755 D9Bwg1e MGI:MGI:106407 +52756 D9Ucl1e MGI:MGI:104342 +52757 D17Wsu19e MGI:MGI:106286 +52758 D7Wsu170e MGI:MGI:107890 +52759 D7Wsu190e MGI:MGI:1099791 +52760 D7Bwg1289e MGI:MGI:106453 +52761 D6Bwg0425e MGI:MGI:106469 +52762 D3Bwg0800e MGI:MGI:106529 +52763 D2Bwg0377e MGI:MGI:106567 +52764 D1Bwg0420e MGI:MGI:106578 +52765 D1Bwg0318e MGI:MGI:106579 +52766 D1Bwg0348e MGI:MGI:107360 +52767 D1Wsu198e MGI:MGI:1099794 +52768 D6Wsu189e MGI:MGI:1099799 +52769 D4Wsu199e MGI:MGI:1099822 +52770 D9Wsu191e MGI:MGI:1099825 +52771 D4Wsu188e MGI:MGI:1099836 +52772 D14Gi1e MGI:MGI:1331649 +52773 D15Aus76rse MGI:MGI:90171 +52774 D4Bwg23e MGI:MGI:102807 +52775 D4Bwg96e MGI:MGI:105973 +52776 D11Ucl1e MGI:MGI:104344 +52777 D17Wsu117e MGI:MGI:106289 +52778 D13Wsu121e MGI:MGI:107253 +52779 D16Wsu194e MGI:MGI:1196336 +52780 D9Mgc47e MGI:MGI:1330289 +52781 D6Bwg16e MGI:MGI:105535 +52782 D16Bwg1168e MGI:MGI:106298 +52783 D15Bwg0213e MGI:MGI:106319 +52784 D11Bwg0388e MGI:MGI:106372 +52785 D10Bwg2001e MGI:MGI:106386 +52786 D10Bwg0812e MGI:MGI:106391 +52787 D10Bwg0719e MGI:MGI:106395 +52788 D10Bwg0322e MGI:MGI:106398 +52789 D11Bwg1529e MGI:MGI:107264 +52790 D11Wsu197e MGI:MGI:1099813 +52791 D18Wsu187e MGI:MGI:1099830 +52792 D9Bwg001e MGI:MGI:107284 +52793 Fam3b MGI:MGI:1270150|Ensembl:ENSMUSG00000022938|Vega:OTTMUSG00000020067 +52794 D16Jhu21e MGI:MGI:1310003 +52796 D10Jhu15e MGI:MGI:1336207 +52797 D4Ag2e MGI:MGI:92642 +52798 D4Ag1e MGI:MGI:92643 +52799 D16Jhu11e MGI:MGI:1270146 +52800 D16Jhu23e MGI:MGI:1338067 +52803 D7Bwg0612e MGI:MGI:106456 +52805 D2Bwg1072e MGI:MGI:106560 +52806 D2Bwg0405e MGI:MGI:106566 +52808 Tspyl2 MGI:MGI:106244|Ensembl:ENSMUSG00000041096|Vega:OTTMUSG00000019701 +52810 D9Bwg1411e MGI:MGI:106409 +52815 Ldhd MGI:MGI:106428|Ensembl:ENSMUSG00000031958|Vega:OTTMUSG00000038174 +52819 D7Bwg0826e MGI:MGI:106455 +52821 D5Bwg1346e MGI:MGI:106483 +52822 Rufy3 MGI:MGI:106484|Ensembl:ENSMUSG00000029291|Vega:OTTMUSG00000055391 +52824 D5Bwg0676e MGI:MGI:106486 +52825 D5Bwg0670e MGI:MGI:106487 +52829 Lurap1l MGI:MGI:106510|Ensembl:ENSMUSG00000048706|Vega:OTTMUSG00000000392 +52830 Pnrc2 MGI:MGI:106512|Ensembl:ENSMUSG00000028675|Vega:OTTMUSG00000009795 +52837 Tmx4 MGI:MGI:106558|Ensembl:ENSMUSG00000034723|Vega:OTTMUSG00000015451 +52838 Dnlz MGI:MGI:106559|Ensembl:ENSMUSG00000075467|Vega:OTTMUSG00000012773 +52840 Dbndd2 MGI:MGI:106562|Ensembl:ENSMUSG00000017734|Vega:OTTMUSG00000001091 +52841 D2Bwg0886e MGI:MGI:106563 +52846 Cnot11 MGI:MGI:106580|Ensembl:ENSMUSG00000003135|Vega:OTTMUSG00000026590 +52850 Sgsm1 MGI:MGI:107320|Ensembl:ENSMUSG00000042216|Vega:OTTMUSG00000025828 +52854 D2Bwg0161e MGI:MGI:107355 +52855 Lair1 MGI:MGI:105492|Ensembl:ENSMUSG00000055541|Vega:OTTMUSG00000027896 +52856 Mtg2 MGI:MGI:106565|Ensembl:ENSMUSG00000039069|Vega:OTTMUSG00000016242 +52857 Gramd1a MGI:MGI:105490|Ensembl:ENSMUSG00000001248|Vega:OTTMUSG00000045673 +52858 Cdipt MGI:MGI:105491|Ensembl:ENSMUSG00000030682|Vega:OTTMUSG00000058362 +52861 D19Bwg0552e MGI:MGI:106255 +52862 D18Bwg1488e MGI:MGI:106267 +52863 D16Bwg1278e MGI:MGI:106297 +52864 Slx4 MGI:MGI:106299|Ensembl:ENSMUSG00000039738|Vega:OTTMUSG00000017267 +52874 Pum3 MGI:MGI:106253|Ensembl:ENSMUSG00000041360 +52880 D15Bwg0340e MGI:MGI:106318 +52882 Rgs7bp MGI:MGI:106334|Ensembl:ENSMUSG00000021719 +52884 Mgll-rs2 MGI:MGI:106336 +52885 D12Bwg1319e MGI:MGI:106342 +52888 D12Bwg0892e MGI:MGI:106345 +52892 Sco1 MGI:MGI:106362|Ensembl:ENSMUSG00000069844|Vega:OTTMUSG00000005911 +52897 Rbfox3 MGI:MGI:106368|Ensembl:ENSMUSG00000025576|Vega:OTTMUSG00000003975 +52898 Rnasek MGI:MGI:106369|Ensembl:ENSMUSG00000040904|Ensembl:ENSMUSG00000093989|Vega:OTTMUSG00000006038|Vega:OTTMUSG00000042288 +52902 D10Bwg1070e MGI:MGI:106389 +52906 Ahi1 MGI:MGI:87971|Ensembl:ENSMUSG00000019986|Vega:OTTMUSG00000063871 +52908 D17Bwg1496e MGI:MGI:107230 +52912 D10Bwg0424e MGI:MGI:107273 +52913 D10Bwg0134e MGI:MGI:107274 +52915 Zmiz2 MGI:MGI:106374|Ensembl:ENSMUSG00000041164|Vega:OTTMUSG00000000781 +52916 D15Uci1e MGI:MGI:1095740 +52917 D17Ph5e MGI:MGI:103273 +52918 D17Ph4e MGI:MGI:103274 +52919 D5Mnl25e MGI:MGI:107753 +52935 8L MGI:MGI:1336987 +52936 2E MGI:MGI:1337010 +52937 1L MGI:MGI:1337015 +52938 D.seq MGI:MGI:1339950 +52939 G.seq MGI:MGI:1339964 +52940 B.seq MGI:MGI:1339966 +52941 F.seq MGI:MGI:1340000 +52942 A.seq MGI:MGI:1340004 +52943 E.seq MGI:MGI:1340039 +52944 C.seq MGI:MGI:1340057 +52977 1h9 MGI:MGI:1341801 +52978 3a4 MGI:MGI:1341844 +52979 2b9 MGI:MGI:1341876 +52981 3f1 MGI:MGI:1341897 +52982 18E MGI:MGI:1337007 +52990 M6T7 MGI:MGI:1339992 +52991 O1T7 MGI:MGI:1340005 +52992 B6T7 MGI:MGI:1340018 +52993 NDS9 MGI:MGI:1340025 +52994 B5T7 MGI:MGI:1340040 +52995 K4T7 MGI:MGI:1340056 +52996 3b11 MGI:MGI:1341802 +53001 45K20 MGI:MGI:1350148 +53002 H9SP6 MGI:MGI:1339943 +53003 N13T7 MGI:MGI:1339945 +53004 B6SP6 MGI:MGI:1339948 +53005 O12T7 MGI:MGI:1339954 +53006 L22T7 MGI:MGI:1339985 +53007 N19T7 MGI:MGI:1339987 +53008 O20T7 MGI:MGI:1339988 +53009 K20T7 MGI:MGI:1339994 +53010 K4SP6 MGI:MGI:1339995 +53011 CA9.2 MGI:MGI:1340007 +53012 CA7.4 MGI:MGI:1340008 +53013 CA7.5 MGI:MGI:1340009 +53014 CA7.6 MGI:MGI:1340010 +53015 CA7.7 MGI:MGI:1340011 +53016 CA7.1 MGI:MGI:1340012 +53017 CA7.2 MGI:MGI:1340013 +53018 CA7.3 MGI:MGI:1340014 +53019 I16T7 MGI:MGI:1340016 +53020 CA9.1 MGI:MGI:1340020 +53021 C8SP6 MGI:MGI:1340033 +53022 M6SP6 MGI:MGI:1340043 +53023 B308A MGI:MGI:1346408 +53031 91E7R MGI:MGI:1337076 +53037 N15SP6 MGI:MGI:1339955 +53038 Cprime MGI:MGI:1339959 +53039 CA7.18 MGI:MGI:1339974 +53040 CA7.14 MGI:MGI:1339978 +53041 CA7.15 MGI:MGI:1339979 +53042 CA7.12 MGI:MGI:1339980 +53043 CA7.13 MGI:MGI:1339981 +53044 CA7.17 MGI:MGI:1339982 +53045 CA7.11 MGI:MGI:1339983 +53046 CA7.10 MGI:MGI:1339990 +53047 K20SP6 MGI:MGI:1339991 +53048 CA25.2 MGI:MGI:1340002 +53049 O12SP6 MGI:MGI:1340006 +53050 O20SP6 MGI:MGI:1340015 +53051 CA25.5 MGI:MGI:1340017 +53052 L22SP6 MGI:MGI:1340019 +53053 J14SP6 MGI:MGI:1340022 +53054 F15SP6 MGI:MGI:1340028 +53055 CA83.3 MGI:MGI:1340035 +53056 B22SP6 MGI:MGI:1340041 +53057 I16SP6 MGI:MGI:1340054 +53058 O21SP6 MGI:MGI:1340058 +53059 CAH9.3 MGI:MGI:1340061 +53060 5n7-T7 MGI:MGI:1341101 +53061 195g2B MGI:MGI:1341239 +53062 EC79RR MGI:MGI:1345623 +53063 EC84RL MGI:MGI:1345645 +53064 EC19AR MGI:MGI:1345679 +53082 B3K(I) MGI:MGI:1345614 +53083 B2N(I) MGI:MGI:1345651 +53084 42F4-T7 MGI:MGI:1337069 +53085 M-04373 MGI:MGI:1337071 +53086 M-10625 MGI:MGI:1337077 +53087 M-02922 MGI:MGI:1337083 +53088 46O1-T7 MGI:MGI:1337101 +53089 CA178.8 MGI:MGI:1339940 +53090 CA25.15 MGI:MGI:1339961 +53091 232b10C MGI:MGI:1341075 +53092 232b10D MGI:MGI:1341113 +53093 232b10F MGI:MGI:1341114 +53094 56G1Sp6 MGI:MGI:1341118 +53095 FBLA2-3 MGI:MGI:1341146 +53096 FBLA2-2 MGI:MGI:1341147 +53097 90k2-T7 MGI:MGI:1341170 +53098 162c8A2 MGI:MGI:1341177 +53099 FDBC8-1 MGI:MGI:1341244 +53100 59K2-T7 MGI:MGI:1341294 +53101 Y97m1a3 MGI:MGI:1343106 +53102 Y95m1f5 MGI:MGI:1343128 +53103 Y88m6a6 MGI:MGI:1343134 +53104 Y78m6g9 MGI:MGI:1343141 +53105 Y95m5e3 MGI:MGI:1343162 +53106 Y83m2c2 MGI:MGI:1343163 +53107 EC192RR MGI:MGI:1345616 +53108 EC218RL MGI:MGI:1345624 +53109 EC100RL MGI:MGI:1345642 +53110 EC100RR MGI:MGI:1345655 +53111 EC108RR MGI:MGI:1345658 +53112 ER87F16 MGI:MGI:1345667 +53113 EC351RR MGI:MGI:1345668 +53114 EC185RR MGI:MGI:1345673 +53115 EC218RR MGI:MGI:1345676 +53116 EC351RL MGI:MGI:1345678 +53117 A007110 MGI:MGI:1337022 +53118 M-06942 MGI:MGI:1341115 +53119 M-01174 MGI:MGI:1341145 +53120 B3N(II) MGI:MGI:1345612 +53123 121D10L MGI:MGI:1337011 +53132 B19E(I) MGI:MGI:1345632 +53133 Y11(II) MGI:MGI:1345648 +53134 YE6(II) MGI:MGI:1345665 +53135 283n3-T7 MGI:MGI:1341068 +53136 274m9-T7 MGI:MGI:1341167 +53137 220n3-T7 MGI:MGI:1341193 +53138 59K2-Sp6 MGI:MGI:1341210 +53139 167c5-T7 MGI:MGI:1341301 +53140 63N19-T7 MGI:MGI:1341304 +53141 401e9Sp6 MGI:MGI:1341373 +53142 Y94m2h10 MGI:MGI:1343129 +53143 Y91m8f11 MGI:MGI:1343179 +53145 612l16Sp6 MGI:MGI:1341116 +53146 199O21-T7 MGI:MGI:1341124 +53147 279P18Sp6 MGI:MGI:1341154 +53148 236M16Sp6 MGI:MGI:1341276 +53149 579J12Sp6 MGI:MGI:1341358 +53150 256f23-T7 MGI:MGI:1341804 +53151 363o12-T7 MGI:MGI:1341821 +53152 277i15-T7 MGI:MGI:1341912 +53153 RH125-126 MGI:MGI:1345646 +53155 FBLA2-1092 MGI:MGI:1341086 +53156 138d12-Sp6 MGI:MGI:1341191 +53157 2c4d6HYACC MGI:MGI:1341202 +53158 236k12-Sp6 MGI:MGI:1341222 +53159 106I22-Sp6 MGI:MGI:1341225 +53160 187c10-Sp6 MGI:MGI:1341229 +53161 2c8b2-1092 MGI:MGI:1341263 +53162 199O21-Sp6 MGI:MGI:1341270 +53163 175N10-Sp6 MGI:MGI:1341298 +53164 1f8f121092 MGI:MGI:1341353 +53165 277i15-SP6 MGI:MGI:1341863 +53166 23.MHAa89f11.seq MGI:MGI:1349413 +53167 232b10HYACC MGI:MGI:1341183 +53168 6c13f9-1092 MGI:MGI:1341249 +53169 MHAa83a1 MGI:MGI:1316675 +53170 6d12h11-1092 MGI:MGI:1341306 +53171 MHAa77c12 MGI:MGI:1316719 +53181 38.MMHAP67FLE5.seq MGI:MGI:1349440 +53182 MHAA30G12.seq MGI:MGI:1337116 +53224 44.MHAa42h8.seq MGI:MGI:1338070 +53230 3B1 MGI:MGI:1341127 +53287 201E9 MGI:MGI:1341196 +53288 03.MMHAP34FRA.seq MGI:MGI:1337005 +53289 630D9T7 MGI:MGI:1339942 +53290 524K7T7 MGI:MGI:1339944 +53291 475D1T7 MGI:MGI:1339952 +53292 538C3T7 MGI:MGI:1339965 +53293 433B7T7 MGI:MGI:1339993 +53294 410O9T7 MGI:MGI:1339996 +53295 645M6T7 MGI:MGI:1340037 +53296 200C3 MGI:MGI:1341108 +53297 41D19 MGI:MGI:1341213 +53298 55D13 MGI:MGI:1341236 +53299 5Sp6 MGI:MGI:1341905 +53300 16.MMHAP64FLF1.seq MGI:MGI:1337039 +53301 380N16T7 MGI:MGI:1340023 +53302 561O14T7 MGI:MGI:1340059 +53303 386N23T7 MGI:MGI:1340060 +53304 412I12 MGI:MGI:1341126 +53305 235M8.T7 MGI:MGI:1342277 +53306 23H6sc34 MGI:MGI:1342298 +53307 235M8.Sp6 MGI:MGI:1342297 +53308 MCA1 MGI:MGI:1345657 +53309 332I15.Sp6 MGI:MGI:1342281 +53310 Dlg3 MGI:MGI:1888986|Ensembl:ENSMUSG00000000881|Vega:OTTMUSG00000016499 +53311 Mybph MGI:MGI:1858196|Ensembl:ENSMUSG00000042451|Vega:OTTMUSG00000049674 +53312 Nub1 MGI:MGI:1889001|Ensembl:ENSMUSG00000028954|Vega:OTTMUSG00000053708 +53313 Atp2a3 MGI:MGI:1194503|Ensembl:ENSMUSG00000020788|Vega:OTTMUSG00000006323 +53314 Batf MGI:MGI:1859147|Ensembl:ENSMUSG00000034266|Vega:OTTMUSG00000016692 +53315 Sult1d1 MGI:MGI:1926341|Ensembl:ENSMUSG00000029273|Vega:OTTMUSG00000035956 +53317 Plrg1 MGI:MGI:1858197|Ensembl:ENSMUSG00000027998|Vega:OTTMUSG00000029843 +53318 Pdlim3 MGI:MGI:1859274|Ensembl:ENSMUSG00000031636|Vega:OTTMUSG00000061186 +53319 Nxf1 MGI:MGI:1858330|Ensembl:ENSMUSG00000010097|Vega:OTTMUSG00000044877 +53320 Folh1 MGI:MGI:1858193|Ensembl:ENSMUSG00000001773|Vega:OTTMUSG00000037777 +53321 Cntnap1 MGI:MGI:1858201|Ensembl:ENSMUSG00000017167|Vega:OTTMUSG00000002728 +53322 Nucb2 MGI:MGI:1858179|Ensembl:ENSMUSG00000030659|Vega:OTTMUSG00000043201 +53323 Ube2k MGI:MGI:1858216|Ensembl:ENSMUSG00000029203|Vega:OTTMUSG00000028413 +53324 Nptx2 MGI:MGI:1858209|Ensembl:ENSMUSG00000059991|Vega:OTTMUSG00000054975 +53325 Banp MGI:MGI:1889023|Ensembl:ENSMUSG00000025316|Vega:OTTMUSG00000036899 +53328 Pgrmc1 MGI:MGI:1858305|Ensembl:ENSMUSG00000006373|Vega:OTTMUSG00000017101 +53330 Vamp4 MGI:MGI:1858730|Ensembl:ENSMUSG00000026696|Vega:OTTMUSG00000033107 +53331 Stx7 MGI:MGI:1858210|Ensembl:ENSMUSG00000019998 +53332 Mtmr1 MGI:MGI:1858271|Ensembl:ENSMUSG00000015214|Vega:OTTMUSG00000017893 +53333 Tomm40 MGI:MGI:1858259|Ensembl:ENSMUSG00000002984|Vega:OTTMUSG00000038241 +53334 Gosr1 MGI:MGI:1858260|Ensembl:ENSMUSG00000010392|Vega:OTTMUSG00000006238 +53356 Eif3g MGI:MGI:1858258|Ensembl:ENSMUSG00000070319|Vega:OTTMUSG00000063002 +53357 Pla2g6 MGI:MGI:1859152|Ensembl:ENSMUSG00000042632|Vega:OTTMUSG00000037241 +53374 Chst3 MGI:MGI:1858224|Ensembl:ENSMUSG00000057337|Vega:OTTMUSG00000035235 +53375 Mtx2 MGI:MGI:1859652|Ensembl:ENSMUSG00000027099|Vega:OTTMUSG00000016594 +53376 Usp2 MGI:MGI:1858178|Ensembl:ENSMUSG00000032010|Vega:OTTMUSG00000042086 +53378 Sdcbp MGI:MGI:1337026|Ensembl:ENSMUSG00000028249|Vega:OTTMUSG00000004316 +53379 Hnrnpa2b1 MGI:MGI:104819|Ensembl:ENSMUSG00000004980|Vega:OTTMUSG00000057601 +53380 Psmd10 MGI:MGI:1858898|Ensembl:ENSMUSG00000031429|Vega:OTTMUSG00000018915 +53381 Prdx4 MGI:MGI:1859815|Ensembl:ENSMUSG00000025289|Vega:OTTMUSG00000019347 +53382 Txnl1 MGI:MGI:1860078|Ensembl:ENSMUSG00000024583 +53404 Atoh7 MGI:MGI:1355553|Ensembl:ENSMUSG00000036816 +53412 Ppp1r3c MGI:MGI:1858229|Ensembl:ENSMUSG00000067279 +53413 Exoc7 MGI:MGI:1859270|Ensembl:ENSMUSG00000020792|Vega:OTTMUSG00000003840 +53414 Bysl MGI:MGI:1858419|Ensembl:ENSMUSG00000023988 +53415 Htatip2 MGI:MGI:1859271|Ensembl:ENSMUSG00000039745|Vega:OTTMUSG00000058997 +53416 Stk39 MGI:MGI:1858416|Ensembl:ENSMUSG00000027030|Vega:OTTMUSG00000012975 +53417 Hif3a MGI:MGI:1859778|Ensembl:ENSMUSG00000004328|Vega:OTTMUSG00000022817 +53418 B4galt2 MGI:MGI:1858493|Ensembl:ENSMUSG00000028541|Vega:OTTMUSG00000008664 +53419 Corin MGI:MGI:1349451|Ensembl:ENSMUSG00000005220|Vega:OTTMUSG00000039797 +53420 Syt5 MGI:MGI:1926368|Ensembl:ENSMUSG00000004961|Vega:OTTMUSG00000058457 +53421 Sec61a1 MGI:MGI:1858417|Ensembl:ENSMUSG00000030082|Vega:OTTMUSG00000023092 +53422 Ybx2 MGI:MGI:1096372|Ensembl:ENSMUSG00000018554|Vega:OTTMUSG00000006029 +53424 Tsnax MGI:MGI:1855672|Ensembl:ENSMUSG00000056820|Vega:OTTMUSG00000061590 +53598 Dctn3 MGI:MGI:1859251|Ensembl:ENSMUSG00000028447|Vega:OTTMUSG00000006679 +53599 Cd164 MGI:MGI:1859568|Ensembl:ENSMUSG00000019818|Vega:OTTMUSG00000045007 +53600 Timm23 MGI:MGI:1858317|Ensembl:ENSMUSG00000013701|Vega:OTTMUSG00000036490 +53601 Pcdh12 MGI:MGI:1855700|Ensembl:ENSMUSG00000024440|Vega:OTTMUSG00000050571 +53602 Hpcal1 MGI:MGI:1855689|Ensembl:ENSMUSG00000071379 +53603 Tslp MGI:MGI:1855696|Ensembl:ENSMUSG00000024379 +53604 Zpbp MGI:MGI:1855701|Ensembl:ENSMUSG00000020193|Vega:OTTMUSG00000007679 +53605 Nap1l1 MGI:MGI:1855693|Ensembl:ENSMUSG00000058799 +53607 Snrpa MGI:MGI:1855690|Ensembl:ENSMUSG00000061479|Vega:OTTMUSG00000031830 +53608 Map3k6 MGI:MGI:1855691|Ensembl:ENSMUSG00000028862|Vega:OTTMUSG00000010479 +53609 Clasrp MGI:MGI:1855695|Ensembl:ENSMUSG00000061028|Vega:OTTMUSG00000059257 +53610 Nono MGI:MGI:1855692|Ensembl:ENSMUSG00000031311|Vega:OTTMUSG00000018195 +53611 Vti1a MGI:MGI:1855699|Ensembl:ENSMUSG00000024983 +53612 Vti1b MGI:MGI:1855688|Ensembl:ENSMUSG00000021124|Vega:OTTMUSG00000034944 +53614 Reck MGI:MGI:1855698|Ensembl:ENSMUSG00000028476|Vega:OTTMUSG00000007127 +53617 Krt35 MGI:MGI:1858899|Ensembl:ENSMUSG00000048013|Vega:OTTMUSG00000002218 +53618 Fut8 MGI:MGI:1858901|Ensembl:ENSMUSG00000021065 +53619 Blcap MGI:MGI:1858907|Ensembl:ENSMUSG00000067787|Vega:OTTMUSG00000016195 +53620 Vamp5 MGI:MGI:1858622|Ensembl:ENSMUSG00000073002|Vega:OTTMUSG00000057918 +53621 Cnot4 MGI:MGI:1859026|Ensembl:ENSMUSG00000038784|Vega:OTTMUSG00000056105 +53622 Krt85 MGI:MGI:1859268 +53623 Gria3 MGI:MGI:95810|Ensembl:ENSMUSG00000001986|Vega:OTTMUSG00000017323 +53624 Cldn7 MGI:MGI:1859285|Ensembl:ENSMUSG00000018569|Vega:OTTMUSG00000006019 +53625 B3gnt2 MGI:MGI:1889505|Ensembl:ENSMUSG00000051650|Vega:OTTMUSG00000005266 +53626 Insm1 MGI:MGI:1859980|Ensembl:ENSMUSG00000068154|Vega:OTTMUSG00000015694 +53627 Porcn MGI:MGI:1890212|Ensembl:ENSMUSG00000031169|Vega:OTTMUSG00000018131 +53650 D5J2 MGI:MGI:93161 +53651 D7J5 MGI:MGI:93907 +53658 D16J2 MGI:MGI:90450 +53659 D17J2 MGI:MGI:90684 +53660 D2Mc1 MGI:MGI:91952 +53661 D3Mc1 MGI:MGI:92362 +53662 D4Mc1 MGI:MGI:92718 +53663 D4Mc2 MGI:MGI:92719 +53664 D7Hd3 MGI:MGI:93892 +53665 D7Mc1 MGI:MGI:93912 +53666 D7Mc2 MGI:MGI:93913 +53667 D8Mc1 MGI:MGI:94275 +53668 D7Hd1 MGI:MGI:93888 +53669 D8Fcr1 MGI:MGI:94271 +53670 D7Dkj1 MGI:MGI:99269 +53671 D0J8 MGI:MGI:88632 +53673 D6Nds1 MGI:MGI:93787 +53674 D6Nds5 MGI:MGI:93791 +53676 DYByu1 MGI:MGI:95250 +53677 DYByu2 MGI:MGI:95251 +53678 DYByu3 MGI:MGI:95252 +53679 DYByu4 MGI:MGI:95253 +53680 DYByu5 MGI:MGI:95254 +53681 DYByu6 MGI:MGI:95255 +53682 DYByu7 MGI:MGI:95256 +53683 DYByu8 MGI:MGI:95257 +53684 D9Lws1 MGI:MGI:99263 +53685 D4Hrb1 MGI:MGI:99264 +53686 D9Hrb1 MGI:MGI:99265 +53687 D1Lws2 MGI:MGI:99272 +53688 D1Rp5 MGI:MGI:1101774 +53689 D0Rp3 MGI:MGI:88673 +53690 D0Rp5 MGI:MGI:88674 +53691 D0Rp6 MGI:MGI:88675 +53692 D1Dcw37 MGI:MGI:91396 +53693 D2Mit1 MGI:MGI:91954 +53694 D2Nds2 MGI:MGI:92299 +53695 D3Tu51 MGI:MGI:92637 +53696 D5Pas1 MGI:MGI:93469 +53697 D6Nds4 MGI:MGI:93790 +53700 D7Citb2 MGI:MGI:99270 +53701 D9Citb3 MGI:MGI:99271 +53702 D3Tu33 MGI:MGI:101777 +53703 D11Mc1 MGI:MGI:88976 +53704 D12Nyu1 MGI:MGI:89566 +53705 D12Nyu2 MGI:MGI:89570 +53706 D12Nyu3 MGI:MGI:89571 +53707 D12Nyu4 MGI:MGI:89572 +53708 D12Nyu5 MGI:MGI:89573 +53709 D13Mc1 MGI:MGI:89632 +53710 D14Mc1 MGI:MGI:89934 +53711 D16Mc1 MGI:MGI:90453 +53713 D18Pas1 MGI:MGI:91187 +53714 D19Mc1 MGI:MGI:91214 +53715 D4Nds10 MGI:MGI:93036 +53716 D4Smh6b MGI:MGI:93100 +53717 D5H4S62 MGI:MGI:93157 +53718 D5H4S76 MGI:MGI:93158 +53719 D5H4S80 MGI:MGI:93159 +53720 D6H3S18 MGI:MGI:93515 +53722 D7Cwr18 MGI:MGI:93877 +53723 D9H3S92 MGI:MGI:94604 +53724 D9H3S93 MGI:MGI:94605 +53726 DXHXS32 MGI:MGI:95051 +53727 D17Zt5 MGI:MGI:101951 +53728 D17Zt4 MGI:MGI:101952 +53729 D17Zt3 MGI:MGI:101953 +53730 D17Zt2 MGI:MGI:101954 +53731 D17Zt1 MGI:MGI:101955 +53732 D15Nds2 MGI:MGI:90421 +53733 D17Aus9 MGI:MGI:90632 +53734 D17Leh9 MGI:MGI:90729 +53735 D17Tu10 MGI:MGI:90960 +53736 D3Byu17 MGI:MGI:92329 +53738 DXPas23 MGI:MGI:95202 +53739 D7Byu27 MGI:MGI:101778 +53740 D1Byu25 MGI:MGI:102846 +53741 D1Byu26 MGI:MGI:102847 +53742 D1MitA1 MGI:MGI:103259 +53743 D0Tu6 MGI:MGI:88683 +53744 D0Tu7 MGI:MGI:88684 +53745 D0Tu8 MGI:MGI:88685 +53747 D10Led1 MGI:MGI:88709 +53748 D10Nds3 MGI:MGI:88925 +53749 D12Nds1 MGI:MGI:89563 +53750 D13Byu5 MGI:MGI:89609 +53752 D9Ncvs53 MGI:MGI:94836 +53753 D9Ncvs58 MGI:MGI:94841 +53755 D11Hrb1 MGI:MGI:99266 +53756 D13Hrb1 MGI:MGI:99267 +53757 D17Boy1 MGI:MGI:99268 +53758 D0H2S3 MGI:MGI:88629 +53759 D11H4S10 MGI:MGI:88968 +53760 D13Mit31 MGI:MGI:89759 +53761 Prrc2a MGI:MGI:1915467|Ensembl:ENSMUSG00000024393|Vega:OTTMUSG00000037194 +53762 D17Leh12 MGI:MGI:90691 +53763 D2H11S16 MGI:MGI:91939 +53764 D7H19S19 MGI:MGI:93886 +53765 D7H19S51 MGI:MGI:93887 +53766 DXHXS101 MGI:MGI:95043 +53767 DXHXS120 MGI:MGI:95045 +53768 DXHXS178 MGI:MGI:95047 +53769 DXHXS296 MGI:MGI:95050 +53770 DXHXS674 MGI:MGI:95054 +53771 DXHXS676 MGI:MGI:95055 +53773 D15Citb1 MGI:MGI:99849 +53774 D1Fcr2 MGI:MGI:104800 +53775 D12Mcga1 MGI:MGI:89341 +53776 D17Aus3I MGI:MGI:90624 +53777 D17Leh26 MGI:MGI:90701 +53778 D17Leh27 MGI:MGI:90702 +53779 D17Nds41 MGI:MGI:90938 +53780 D18Byu22 MGI:MGI:91009 +53782 DXHXF34 MGI:MGI:95042 +53783 D15Byu21 MGI:MGI:101779 +53784 D0Tu11 MGI:MGI:88676 +53785 D0Tu13 MGI:MGI:88677 +53786 D0Tu15 MGI:MGI:88678 +53787 D0Tu17 MGI:MGI:88679 +53788 D0Tu31 MGI:MGI:88680 +53789 D0Tu44 MGI:MGI:88681 +53790 D0Tu46 MGI:MGI:88682 +53791 Tlr5 MGI:MGI:1858171|Ensembl:ENSMUSG00000079164|Vega:OTTMUSG00000050487 +53792 D16H21S16 MGI:MGI:90446 +53793 D16H21S52 MGI:MGI:90447 +53794 D17H21S56 MGI:MGI:90663 +53795 D2H11S149 MGI:MGI:91938 +53796 D2H11S408 MGI:MGI:91940 +53797 D2H11S411 MGI:MGI:91941 +53798 D2H11S412 MGI:MGI:91942 +53799 DXHXS144E MGI:MGI:95046 +53802 D17Aus3II MGI:MGI:90625 +53805 D17H16S125 MGI:MGI:90661 +53806 D17H16S259 MGI:MGI:90662 +53808 D7H19F11S1 MGI:MGI:93884 +53809 D17Leh86t MGI:MGI:90727 +53810 D7Cwr3P MGI:MGI:102517 +53812 D17Tu53A MGI:MGI:90994 +53813 D17Tu53B MGI:MGI:90995 +53814 Oaz3 MGI:MGI:1858170|Ensembl:ENSMUSG00000028141|Vega:OTTMUSG00000042345 +53815 D17Leh108A MGI:MGI:90685 +53816 D17Leh108B MGI:MGI:90686 +53817 Ddx39b MGI:MGI:99240|Ensembl:ENSMUSG00000019432|Vega:OTTMUSG00000037268 +53818 Bat1b MGI:MGI:99241 +53856 Prg3 MGI:MGI:1858200|Ensembl:ENSMUSG00000027072|Vega:OTTMUSG00000013452 +53857 Tuba8 MGI:MGI:1858225|Ensembl:ENSMUSG00000030137|Vega:OTTMUSG00000022202 +53858 Rwdd2b MGI:MGI:1858215|Ensembl:ENSMUSG00000041079|Vega:OTTMUSG00000019953 +53859 Map3k14 MGI:MGI:1858204|Ensembl:ENSMUSG00000020941|Vega:OTTMUSG00000003049 +53860 Sept9 MGI:MGI:1858222|Ensembl:ENSMUSG00000059248|Vega:OTTMUSG00000003788 +53861 Zranb2 MGI:MGI:1858211|Ensembl:ENSMUSG00000028180|Vega:OTTMUSG00000016669 +53867 Col5a3 MGI:MGI:1858212|Ensembl:ENSMUSG00000004098|Vega:OTTMUSG00000022343 +53868 Rab25 MGI:MGI:1858203|Ensembl:ENSMUSG00000008601|Vega:OTTMUSG00000027246 +53869 Rab11a MGI:MGI:1858202|Ensembl:ENSMUSG00000004771|Vega:OTTMUSG00000036848 +53870 Cntn6 MGI:MGI:1858223|Ensembl:ENSMUSG00000030092|Vega:OTTMUSG00000033392 +53871 Pkd2l2 MGI:MGI:1858231|Ensembl:ENSMUSG00000014503 +53872 Caprin1 MGI:MGI:1858234|Ensembl:ENSMUSG00000027184|Vega:OTTMUSG00000014878 +53873 Ear7 MGI:MGI:1858205 +53874 Ear8 MGI:MGI:1858206 +53875 Ear9 MGI:MGI:1858207 +53876 Ear3 MGI:MGI:1858237 +53877 Ear4 MGI:MGI:1858238 +53878 Svs2 MGI:MGI:1858275|Ensembl:ENSMUSG00000040132|Vega:OTTMUSG00000001080 +53880 Naip7 MGI:MGI:1858256 +53881 Slc5a3 MGI:MGI:1858226|Ensembl:ENSMUSG00000089774|Vega:OTTMUSG00000025870 +53883 Celsr2 MGI:MGI:1858235|Ensembl:ENSMUSG00000068740|Vega:OTTMUSG00000007107 +53885 Nphp1 MGI:MGI:1858233|Ensembl:ENSMUSG00000027378|Vega:OTTMUSG00000016097 +53886 Cdkl2 MGI:MGI:1858227|Ensembl:ENSMUSG00000029403|Vega:OTTMUSG00000025604 +53887 Ear-ps1 MGI:MGI:1858247 +53890 Sart3 MGI:MGI:1858230|Ensembl:ENSMUSG00000018974|Vega:OTTMUSG00000054497 +53892 Ppm1d MGI:MGI:1858214|Ensembl:ENSMUSG00000020525|Vega:OTTMUSG00000001033 +53893 Nudt5 MGI:MGI:1858232|Ensembl:ENSMUSG00000025817|Vega:OTTMUSG00000010875 +53895 Clpp MGI:MGI:1858213|Ensembl:ENSMUSG00000002660 +53896 Slc7a10 MGI:MGI:1858261|Ensembl:ENSMUSG00000030495|Vega:OTTMUSG00000027210 +53897 Gal3st1 MGI:MGI:1858277|Ensembl:ENSMUSG00000049721|Vega:OTTMUSG00000005048 +53898 Naip3-ps1 MGI:MGI:1858253 +53899 Naip3-ps2 MGI:MGI:1858254 +53900 Naip3-ps3 MGI:MGI:1858255 +53901 Rcan2 MGI:MGI:1858219|Ensembl:ENSMUSG00000039601 +53902 Rcan3 MGI:MGI:1858220|Ensembl:ENSMUSG00000059713|Vega:OTTMUSG00000009732 +53906 Phgr1 MGI:MGI:1858382|Ensembl:ENSMUSG00000046804|Vega:OTTMUSG00000015634 +53914 Tallbcr MGI:MGI:1858384 +53945 Slc40a1 MGI:MGI:1315204|Ensembl:ENSMUSG00000025993|Vega:OTTMUSG00000046528 +53951 Gpatch11 MGI:MGI:1858435|Ensembl:ENSMUSG00000050668 +53954 W77162 MGI:MGI:1858446 +53956 AA855340 MGI:MGI:1858433 +53957 AA546796 MGI:MGI:1858434 +53958 AU035318 MGI:MGI:1858436 +53959 AA914427 MGI:MGI:1858439 +53960 AA066038 MGI:MGI:1858440 +53961 9530053J19Rik MGI:MGI:1858441 +53963 D630030B22Rik MGI:MGI:1858443 +53965 9430099O15Rik MGI:MGI:1858445 +53970 Rfx5 MGI:MGI:1858421|Ensembl:ENSMUSG00000005774|Vega:OTTMUSG00000019670 +53972 Ngef MGI:MGI:1858414|Ensembl:ENSMUSG00000026259|Vega:OTTMUSG00000036755 +53973 Cyp3a41a MGI:MGI:1858451|Ensembl:ENSMUSG00000075551|Vega:OTTMUSG00000055073 +53975 Ddx20 MGI:MGI:1858415|Ensembl:ENSMUSG00000027905|Vega:OTTMUSG00000029585 +53978 Lpar2 MGI:MGI:1858422|Ensembl:ENSMUSG00000031861 +53993 D16Wis1 MGI:MGI:892901 +53994 D16Jhu28 MGI:MGI:1338048 +53995 D16Jhu35 MGI:MGI:1338003 +53997 D16Jhu26 MGI:MGI:1338051 +53998 D16Jhu27 MGI:MGI:1338052 +53999 D16Jhu24 MGI:MGI:1338053 +54000 D16Jhu25 MGI:MGI:1338054 +54001 D16Jhu30 MGI:MGI:1338060 +54003 Nell2 MGI:MGI:1858510|Ensembl:ENSMUSG00000022454 +54004 Diaph2 MGI:MGI:1858500|Ensembl:ENSMUSG00000034480|Vega:OTTMUSG00000018669 +54006 Deaf1 MGI:MGI:1858496|Ensembl:ENSMUSG00000058886|Vega:OTTMUSG00000060251 +54120 Gipc2 MGI:MGI:1889209|Ensembl:ENSMUSG00000039131|Vega:OTTMUSG00000031664 +54122 Uevld MGI:MGI:1860490|Ensembl:ENSMUSG00000043262|Vega:OTTMUSG00000027379 +54123 Irf7 MGI:MGI:1859212|Ensembl:ENSMUSG00000025498|Vega:OTTMUSG00000024538 +54124 Cks1b MGI:MGI:1889208|Ensembl:ENSMUSG00000028044|Vega:OTTMUSG00000022072 +54125 Polm MGI:MGI:1860191|Ensembl:ENSMUSG00000020474|Vega:OTTMUSG00000005101 +54126 Arhgef7 MGI:MGI:1860493|Ensembl:ENSMUSG00000031511|Vega:OTTMUSG00000021108 +54127 Rps28 MGI:MGI:1859516|Ensembl:ENSMUSG00000067288|Vega:OTTMUSG00000037209 +54128 Pmm2 MGI:MGI:1859214|Ensembl:ENSMUSG00000022711|Vega:OTTMUSG00000025198 +54130 Actr1a MGI:MGI:1858964|Ensembl:ENSMUSG00000025228 +54131 Irf3 MGI:MGI:1859179|Ensembl:ENSMUSG00000003184|Vega:OTTMUSG00000020438 +54132 Pdlim1 MGI:MGI:1860611|Ensembl:ENSMUSG00000055044|Vega:OTTMUSG00000043391 +54135 Lsr MGI:MGI:1927471|Ensembl:ENSMUSG00000001247|Vega:OTTMUSG00000022193 +54137 Acrbp MGI:MGI:1859515|Ensembl:ENSMUSG00000072770|Vega:OTTMUSG00000024302 +54138 Atxn10 MGI:MGI:1859293|Ensembl:ENSMUSG00000016541 +54139 Irf6 MGI:MGI:1859211|Ensembl:ENSMUSG00000026638|Vega:OTTMUSG00000033402 +54140 Avpr1a MGI:MGI:1859216|Ensembl:ENSMUSG00000020123|Vega:OTTMUSG00000020920 +54141 Spag5 MGI:MGI:1927470|Ensembl:ENSMUSG00000002055|Vega:OTTMUSG00000000103 +54150 Rdh7 MGI:MGI:1860517|Ensembl:ENSMUSG00000040134|Vega:OTTMUSG00000027613 +54151 Cyhr1 MGI:MGI:1859320|Ensembl:ENSMUSG00000053929|Vega:OTTMUSG00000040104 +54152 Dnal4 MGI:MGI:1859217|Ensembl:ENSMUSG00000022420|Vega:OTTMUSG00000034900 +54153 Rasa4 MGI:MGI:1858600|Ensembl:ENSMUSG00000004952|Vega:OTTMUSG00000025403 +54156 Egfl6 MGI:MGI:1858599|Ensembl:ENSMUSG00000000402|Vega:OTTMUSG00000019543 +54159 Rnase2b MGI:MGI:1858598|Ensembl:ENSMUSG00000059606 +54160 Copg2 MGI:MGI:1858683|Ensembl:ENSMUSG00000025607|Vega:OTTMUSG00000014455 +54161 Copg1 MGI:MGI:1858696|Ensembl:ENSMUSG00000030058|Vega:OTTMUSG00000022960 +54167 Icos MGI:MGI:1858745|Ensembl:ENSMUSG00000026009|Vega:OTTMUSG00000002307 +54169 Kat6b MGI:MGI:1858746|Ensembl:ENSMUSG00000021767|Vega:OTTMUSG00000043207 +54170 Rragc MGI:MGI:1858751|Ensembl:ENSMUSG00000028646|Vega:OTTMUSG00000008994 +54188 Cpsf4 MGI:MGI:1861602|Ensembl:ENSMUSG00000029625|Vega:OTTMUSG00000023017 +54189 Rabep1 MGI:MGI:1860236|Ensembl:ENSMUSG00000020817|Vega:OTTMUSG00000006080 +54192 Pbsn MGI:MGI:1860484|Ensembl:ENSMUSG00000000003|Vega:OTTMUSG00000017891 +54194 Akap8l MGI:MGI:1860606|Ensembl:ENSMUSG00000002625 +54195 Gucy1b3 MGI:MGI:1860604|Ensembl:ENSMUSG00000028005|Vega:OTTMUSG00000051753 +54196 Pabpn1 MGI:MGI:1859158|Ensembl:ENSMUSG00000022194|Vega:OTTMUSG00000037620 +54197 Rnf5 MGI:MGI:1860076|Ensembl:ENSMUSG00000015478|Vega:OTTMUSG00000037075 +54198 Snx3 MGI:MGI:1860188|Ensembl:ENSMUSG00000019804|Vega:OTTMUSG00000019461 +54199 Ccrl2 MGI:MGI:1920904|Ensembl:ENSMUSG00000043953|Vega:OTTMUSG00000052504 +54200 Sult2b1 MGI:MGI:1926342|Ensembl:ENSMUSG00000003271|Vega:OTTMUSG00000022561 +54201 Zfp316 MGI:MGI:1860402|Ensembl:ENSMUSG00000046658|Vega:OTTMUSG00000033379 +54204 Sept1 MGI:MGI:1858916|Ensembl:ENSMUSG00000000486|Vega:OTTMUSG00000022181 +54208 Arl6ip1 MGI:MGI:1858943|Ensembl:ENSMUSG00000030654|Vega:OTTMUSG00000057156 +54214 Golga4 MGI:MGI:1859646|Ensembl:ENSMUSG00000038708|Vega:OTTMUSG00000061786 +54215 Cd160 MGI:MGI:1860383|Ensembl:ENSMUSG00000038304|Vega:OTTMUSG00000022013 +54216 Pcdh7 MGI:MGI:1860487|Ensembl:ENSMUSG00000029108|Vega:OTTMUSG00000050929 +54217 Rpl36 MGI:MGI:1860603|Ensembl:ENSMUSG00000057863 +54218 B3galt4 MGI:MGI:1859517|Ensembl:ENSMUSG00000067370|Vega:OTTMUSG00000037084 +54219 Cd320 MGI:MGI:1860083|Ensembl:ENSMUSG00000002308|Vega:OTTMUSG00000037211 +54324 Arhgef5 MGI:MGI:1858952|Ensembl:ENSMUSG00000033542|Vega:OTTMUSG00000043554 +54325 Elovl1 MGI:MGI:1858959|Ensembl:ENSMUSG00000006390|Vega:OTTMUSG00000008772 +54326 Elovl2 MGI:MGI:1858960|Ensembl:ENSMUSG00000021364|Vega:OTTMUSG00000029813 +54338 Slc23a2 MGI:MGI:1859682|Ensembl:ENSMUSG00000027340|Vega:OTTMUSG00000015783 +54339 Tes3-ps MGI:MGI:3582925 +54342 Gnpnat1 MGI:MGI:1858963|Ensembl:ENSMUSG00000037722 +54343 Atf7ip MGI:MGI:1858965|Ensembl:ENSMUSG00000030213|Vega:OTTMUSG00000047948 +54351 Elp5 MGI:MGI:1859017|Ensembl:ENSMUSG00000018565|Vega:OTTMUSG00000006030 +54352 Irx5 MGI:MGI:1859086|Ensembl:ENSMUSG00000031737|Vega:OTTMUSG00000040089 +54353 Skap2 MGI:MGI:1889206|Ensembl:ENSMUSG00000059182|Vega:OTTMUSG00000057619 +54354 Rassf5 MGI:MGI:1926375|Ensembl:ENSMUSG00000026430|Vega:OTTMUSG00000021554 +54357 Epb41l4b MGI:MGI:1859149|Ensembl:ENSMUSG00000028434|Vega:OTTMUSG00000007315 +54364 Rpp30 MGI:MGI:1859683|Ensembl:ENSMUSG00000024800 +54366 Ctnnal1 MGI:MGI:1859649|Ensembl:ENSMUSG00000038816|Vega:OTTMUSG00000007317 +54367 Zfp326 MGI:MGI:1927246|Ensembl:ENSMUSG00000029290|Vega:OTTMUSG00000023428 +54368 Gp9 MGI:MGI:1860137|Ensembl:ENSMUSG00000030054|Vega:OTTMUSG00000057257 +54369 Nme6 MGI:MGI:1861676|Ensembl:ENSMUSG00000032478|Vega:OTTMUSG00000030951 +54371 Chst2 MGI:MGI:1891160|Ensembl:ENSMUSG00000033350|Vega:OTTMUSG00000046997 +54373 Prss16 MGI:MGI:1859181|Ensembl:ENSMUSG00000006179|Vega:OTTMUSG00000000726 +54375 Azin1 MGI:MGI:1859169|Ensembl:ENSMUSG00000037458|Vega:OTTMUSG00000024581 +54376 Cacng3 MGI:MGI:1859165|Ensembl:ENSMUSG00000066189|Vega:OTTMUSG00000044341 +54377 Cacng4 MGI:MGI:1859167|Ensembl:ENSMUSG00000020723|Vega:OTTMUSG00000003107 +54378 Cacng6 MGI:MGI:1859168|Ensembl:ENSMUSG00000078815|Vega:OTTMUSG00000044342 +54380 Smarcal1 MGI:MGI:1859183|Ensembl:ENSMUSG00000039354|Vega:OTTMUSG00000021499 +54381 Cpq MGI:MGI:1889205|Ensembl:ENSMUSG00000039007 +54382 Tcstv1 MGI:MGI:1933437|Ensembl:ENSMUSG00000096284|Vega:OTTMUSG00000047880 +54383 Phc2 MGI:MGI:1860454|Ensembl:ENSMUSG00000028796|Vega:OTTMUSG00000009456 +54384 Mtmr7 MGI:MGI:1891693|Ensembl:ENSMUSG00000039431|Vega:OTTMUSG00000038176 +54387 Mcm3ap MGI:MGI:1930089|Ensembl:ENSMUSG00000001150 +54388 Hils1 MGI:MGI:2136691|Ensembl:ENSMUSG00000038994|Vega:OTTMUSG00000001500 +54390 Sit1 MGI:MGI:1889342|Ensembl:ENSMUSG00000028460|Vega:OTTMUSG00000006916 +54391 Rfk MGI:MGI:1914688|Ensembl:ENSMUSG00000024712|Vega:OTTMUSG00000028427 +54392 Ncapg MGI:MGI:1930197|Ensembl:ENSMUSG00000015880|Vega:OTTMUSG00000027810 +54393 Gabbr1 MGI:MGI:1860139|Ensembl:ENSMUSG00000024462|Vega:OTTMUSG00000037319 +54394 Crlf3 MGI:MGI:1860086|Ensembl:ENSMUSG00000017561|Vega:OTTMUSG00000000187 +54396 Irgm2 MGI:MGI:1926262|Ensembl:ENSMUSG00000069874|Vega:OTTMUSG00000005725 +54397 Ppt2 MGI:MGI:1860075|Ensembl:ENSMUSG00000015474|Vega:OTTMUSG00000035857 +54399 Bet1l MGI:MGI:1913128|Ensembl:ENSMUSG00000025484|Vega:OTTMUSG00000060436 +54401 Ywhab MGI:MGI:1891917|Ensembl:ENSMUSG00000018326|Vega:OTTMUSG00000016138 +54402 Stk19 MGI:MGI:1860085|Ensembl:ENSMUSG00000061207|Vega:OTTMUSG00000033101 +54403 Slc4a4 MGI:MGI:1927555|Ensembl:ENSMUSG00000060961|Vega:OTTMUSG00000025881 +54405 Ndufa1 MGI:MGI:1929511|Ensembl:ENSMUSG00000016427|Vega:OTTMUSG00000017127 +54409 Ramp2 MGI:MGI:1859650|Ensembl:ENSMUSG00000001240|Vega:OTTMUSG00000002758 +54411 Atp6ap1 MGI:MGI:109629|Ensembl:ENSMUSG00000019087|Vega:OTTMUSG00000017676 +54418 Fmn2 MGI:MGI:1859252|Ensembl:ENSMUSG00000028354|Vega:OTTMUSG00000050244 +54419 Cldn6 MGI:MGI:1859284|Ensembl:ENSMUSG00000023906|Vega:OTTMUSG00000033036 +54420 Cldn8 MGI:MGI:1859286|Ensembl:ENSMUSG00000050520|Vega:OTTMUSG00000019871 +54422 Barhl1 MGI:MGI:1859288|Ensembl:ENSMUSG00000026805|Vega:OTTMUSG00000011821 +54426 Hgfac MGI:MGI:1859281|Ensembl:ENSMUSG00000029102|Vega:OTTMUSG00000055724 +54427 Dnmt3l MGI:MGI:1859287|Ensembl:ENSMUSG00000000730|Vega:OTTMUSG00000034125 +54445 Unc93b1 MGI:MGI:1859307|Ensembl:ENSMUSG00000036908|Vega:OTTMUSG00000034969 +54446 Nfat5 MGI:MGI:1859333|Ensembl:ENSMUSG00000003847|Vega:OTTMUSG00000033607 +54447 Asah2 MGI:MGI:1859310|Ensembl:ENSMUSG00000024887 +54448 Il1f6 MGI:MGI:1859324|Ensembl:ENSMUSG00000026984|Vega:OTTMUSG00000011962 +54450 Il1f5 MGI:MGI:1859325|Ensembl:ENSMUSG00000026983|Vega:OTTMUSG00000011958 +54451 Cpsf3 MGI:MGI:1859328|Ensembl:ENSMUSG00000054309 +54473 Tollip MGI:MGI:1891808|Ensembl:ENSMUSG00000025139|Vega:OTTMUSG00000023241 +54483 Mefv MGI:MGI:1859396|Ensembl:ENSMUSG00000022534 +54484 Mkrn1 MGI:MGI:1859353|Ensembl:ENSMUSG00000029922|Vega:OTTMUSG00000024514 +54485 Dll4 MGI:MGI:1859388|Ensembl:ENSMUSG00000027314|Vega:OTTMUSG00000015953 +54486 Hpgds MGI:MGI:1859384|Ensembl:ENSMUSG00000029919|Vega:OTTMUSG00000035987 +54519 Apbb1ip MGI:MGI:1861354|Ensembl:ENSMUSG00000026786|Vega:OTTMUSG00000011555 +54524 Syt6 MGI:MGI:1859544|Ensembl:ENSMUSG00000027849|Vega:OTTMUSG00000028617 +54525 Syt7 MGI:MGI:1859545|Ensembl:ENSMUSG00000024743 +54526 Syt10 MGI:MGI:1859546|Ensembl:ENSMUSG00000063260|Vega:OTTMUSG00000021008 +54561 Nap1l3 MGI:MGI:1859565|Ensembl:ENSMUSG00000055733|Vega:OTTMUSG00000018572 +54562 Lrrc6 MGI:MGI:1859553|Ensembl:ENSMUSG00000022375|Vega:OTTMUSG00000037898 +54563 Nup210 MGI:MGI:1859555|Ensembl:ENSMUSG00000030091|Vega:OTTMUSG00000023319 +54598 Calcrl MGI:MGI:1926944|Ensembl:ENSMUSG00000059588|Vega:OTTMUSG00000013406 +54601 Foxo4 MGI:MGI:1891915|Ensembl:ENSMUSG00000042903|Vega:OTTMUSG00000018205 +54604 Pcnx MGI:MGI:1891924|Ensembl:ENSMUSG00000021140 +54607 Socs6 MGI:MGI:1924885|Ensembl:ENSMUSG00000056153|Vega:OTTMUSG00000033185 +54608 Abhd2 MGI:MGI:1914344|Ensembl:ENSMUSG00000039202|Vega:OTTMUSG00000029104 +54609 Ubqln2 MGI:MGI:1860283|Ensembl:ENSMUSG00000050148|Vega:OTTMUSG00000019381 +54610 Tbc1d8 MGI:MGI:1927225|Ensembl:ENSMUSG00000003134|Vega:OTTMUSG00000050277 +54611 Pde3a MGI:MGI:1860764|Ensembl:ENSMUSG00000041741|Vega:OTTMUSG00000046194 +54612 Sfrp5 MGI:MGI:1860298|Ensembl:ENSMUSG00000018822|Vega:OTTMUSG00000021181 +54613 St3gal6 MGI:MGI:1888707|Ensembl:ENSMUSG00000022747|Vega:OTTMUSG00000025631 +54614 Prpf40b MGI:MGI:1925583|Ensembl:ENSMUSG00000023007|Vega:OTTMUSG00000028170 +54615 Npff MGI:MGI:1891708|Ensembl:ENSMUSG00000023052|Vega:OTTMUSG00000044909 +54616 Extl3 MGI:MGI:1860765|Ensembl:ENSMUSG00000021978 +54624 Paf1 MGI:MGI:1923988|Ensembl:ENSMUSG00000003437|Vega:OTTMUSG00000023577 +54630 Prickle3 MGI:MGI:1859635|Ensembl:ENSMUSG00000031145|Vega:OTTMUSG00000017754 +54631 Nphs1 MGI:MGI:1859637|Ensembl:ENSMUSG00000006649|Vega:OTTMUSG00000031081 +54632 Ftsj1 MGI:MGI:1859648|Ensembl:ENSMUSG00000031171|Vega:OTTMUSG00000018132 +54633 Pqbp1 MGI:MGI:1859638|Ensembl:ENSMUSG00000031157|Vega:OTTMUSG00000018001 +54634 Magix MGI:MGI:1859644|Ensembl:ENSMUSG00000031147|Vega:OTTMUSG00000017757 +54635 Pdgfc MGI:MGI:1859631|Ensembl:ENSMUSG00000028019|Vega:OTTMUSG00000028878 +54636 Wdr45 MGI:MGI:1859606|Ensembl:ENSMUSG00000039382|Vega:OTTMUSG00000017803 +54637 Praf2 MGI:MGI:1859607|Ensembl:ENSMUSG00000031149|Vega:OTTMUSG00000017807 +54638 Ccdc22 MGI:MGI:1859608|Ensembl:ENSMUSG00000031143|Vega:OTTMUSG00000016629 +54641 DXImx43e MGI:MGI:1859612 +54642 DXImx44e MGI:MGI:1859613 +54643 DXImx45e MGI:MGI:1859614 +54644 Otud5 MGI:MGI:1859615|Ensembl:ENSMUSG00000031154|Vega:OTTMUSG00000017928 +54645 Gripap1 MGI:MGI:1859616|Ensembl:ENSMUSG00000031153|Vega:OTTMUSG00000017927 +54646 Ppp1r3f MGI:MGI:1859617|Ensembl:ENSMUSG00000039556|Vega:OTTMUSG00000016549 +54648 Ccdc120 MGI:MGI:1859619|Ensembl:ENSMUSG00000031150|Vega:OTTMUSG00000017802 +54650 Sfmbt1 MGI:MGI:1859609|Ensembl:ENSMUSG00000006527|Vega:OTTMUSG00000025116 +54651 Usp27x MGI:MGI:1859645|Ensembl:ENSMUSG00000046269|Vega:OTTMUSG00000016481 +54652 Cacna1f MGI:MGI:1859639|Ensembl:ENSMUSG00000031142|Vega:OTTMUSG00000017707 +54667 Atp8b2 MGI:MGI:1859660|Ensembl:ENSMUSG00000060671|Vega:OTTMUSG00000035241 +54670 Atp8b1 MGI:MGI:1859665|Ensembl:ENSMUSG00000039529 +54672 Adgrg3 MGI:MGI:1859670|Ensembl:ENSMUSG00000060470|Vega:OTTMUSG00000061710 +54673 Sh3glb1 MGI:MGI:1859730|Ensembl:ENSMUSG00000037062|Vega:OTTMUSG00000055022 +54678 Zfp108 MGI:MGI:1891198|Ensembl:ENSMUSG00000030486|Vega:OTTMUSG00000058070 +54683 Prdx5 MGI:MGI:1859821|Ensembl:ENSMUSG00000024953|Vega:OTTMUSG00000021180 +54698 Crtam MGI:MGI:1859822|Ensembl:ENSMUSG00000032021|Vega:OTTMUSG00000042652 +54709 Eif3i MGI:MGI:1860763|Ensembl:ENSMUSG00000028798|Vega:OTTMUSG00000009520 +54710 Hs3st3b1 MGI:MGI:1333853|Ensembl:ENSMUSG00000070407|Vega:OTTMUSG00000007900 +54711 Plagl2 MGI:MGI:1933165|Ensembl:ENSMUSG00000051413|Vega:OTTMUSG00000016732 +54712 Plxnc1 MGI:MGI:1890127|Ensembl:ENSMUSG00000074785|Vega:OTTMUSG00000042667 +54713 Fezf2 MGI:MGI:1859823|Ensembl:ENSMUSG00000021743 +54720 Rcan1 MGI:MGI:1890564|Ensembl:ENSMUSG00000022951 +54721 Tyk2 MGI:MGI:1929470|Ensembl:ENSMUSG00000032175|Vega:OTTMUSG00000063155 +54722 Dfna5 MGI:MGI:1889850|Ensembl:ENSMUSG00000029821|Vega:OTTMUSG00000035970 +54723 Tfip11 MGI:MGI:1930075|Ensembl:ENSMUSG00000029345|Vega:OTTMUSG00000023449 +54725 Cadm1 MGI:MGI:1889272|Ensembl:ENSMUSG00000032076|Vega:OTTMUSG00000024571 +55925 Syt8 MGI:MGI:1859867|Ensembl:ENSMUSG00000031098|Vega:OTTMUSG00000018791 +55927 Hes6 MGI:MGI:1859852|Ensembl:ENSMUSG00000067071|Vega:OTTMUSG00000020919 +55932 Gbp3 MGI:MGI:1926263|Ensembl:ENSMUSG00000028268|Vega:OTTMUSG00000023133 +55934 Rp9 MGI:MGI:2157166|Ensembl:ENSMUSG00000032239|Vega:OTTMUSG00000062377 +55935 Fnbp4 MGI:MGI:1860513|Ensembl:ENSMUSG00000008200|Vega:OTTMUSG00000014273 +55936 Ctps2 MGI:MGI:1933185|Ensembl:ENSMUSG00000031360|Vega:OTTMUSG00000019496 +55938 Apom MGI:MGI:1930124|Ensembl:ENSMUSG00000024391|Vega:OTTMUSG00000037182 +55940 D2Mit19 MGI:MGI:92053 +55942 Sertad1 MGI:MGI:1913438|Ensembl:ENSMUSG00000008384|Vega:OTTMUSG00000023983 +55943 Stx8 MGI:MGI:1890156|Ensembl:ENSMUSG00000020903|Vega:OTTMUSG00000005939 +55944 Eif3d MGI:MGI:1933181|Ensembl:ENSMUSG00000016554 +55946 Ap3m1 MGI:MGI:1929212|Ensembl:ENSMUSG00000021824|Vega:OTTMUSG00000033833 +55947 Dclre1a MGI:MGI:1930042|Ensembl:ENSMUSG00000025077|Vega:OTTMUSG00000043094 +55948 Sfn MGI:MGI:1891831|Ensembl:ENSMUSG00000047281|Vega:OTTMUSG00000011150 +55949 Eef1b2 MGI:MGI:1929520|Ensembl:ENSMUSG00000025967|Vega:OTTMUSG00000002614 +55950 Bri3 MGI:MGI:1933174|Ensembl:ENSMUSG00000047843|Vega:OTTMUSG00000025579 +55951 Mpc1 MGI:MGI:1915240|Ensembl:ENSMUSG00000023861|Vega:OTTMUSG00000032995 +55960 Ebag9 MGI:MGI:1859920|Ensembl:ENSMUSG00000022339 +55961 Slc13a1 MGI:MGI:1859937|Ensembl:ENSMUSG00000029700|Vega:OTTMUSG00000037021 +55963 Slc1a4 MGI:MGI:2135601|Ensembl:ENSMUSG00000020142|Vega:OTTMUSG00000005224 +55978 Ift20 MGI:MGI:1915585|Ensembl:ENSMUSG00000001105|Vega:OTTMUSG00000000139 +55979 Agpat1 MGI:MGI:1932075|Ensembl:ENSMUSG00000034254|Vega:OTTMUSG00000037077 +55980 Impa1 MGI:MGI:1933158|Ensembl:ENSMUSG00000027531|Vega:OTTMUSG00000027767 +55981 Pigb MGI:MGI:1891825|Ensembl:ENSMUSG00000079469|Vega:OTTMUSG00000044840 +55982 Paxip1 MGI:MGI:1890430|Ensembl:ENSMUSG00000002221|Vega:OTTMUSG00000054125 +55983 Pdzrn3 MGI:MGI:1933157|Ensembl:ENSMUSG00000035357|Vega:OTTMUSG00000026975 +55984 Camkk1 MGI:MGI:1891766|Ensembl:ENSMUSG00000020785|Vega:OTTMUSG00000006121 +55985 Cxcl13 MGI:MGI:1888499|Ensembl:ENSMUSG00000023078|Vega:OTTMUSG00000055771 +55987 Cpxm2 MGI:MGI:1926006|Ensembl:ENSMUSG00000030862|Vega:OTTMUSG00000025187 +55988 Snx12 MGI:MGI:1919331|Ensembl:ENSMUSG00000046032|Vega:OTTMUSG00000018199 +55989 Nop58 MGI:MGI:1933184|Ensembl:ENSMUSG00000026020|Vega:OTTMUSG00000047257 +55990 Fmo2 MGI:MGI:1916776|Ensembl:ENSMUSG00000040170|Vega:OTTMUSG00000024135 +55991 Panx1 MGI:MGI:1860055|Ensembl:ENSMUSG00000031934|Vega:OTTMUSG00000035453 +55992 Trim3 MGI:MGI:1860040|Ensembl:ENSMUSG00000036989|Vega:OTTMUSG00000017539 +55993 Msh4 MGI:MGI:1860077|Ensembl:ENSMUSG00000005493|Vega:OTTMUSG00000047398 +55994 Smad9 MGI:MGI:1859993|Ensembl:ENSMUSG00000027796|Vega:OTTMUSG00000021206 +56009 Alyref2 MGI:MGI:1913144|Ensembl:ENSMUSG00000060244|Vega:OTTMUSG00000050081 +56012 Pgam2 MGI:MGI:1933118|Ensembl:ENSMUSG00000020475|Vega:OTTMUSG00000005095 +56013 Srcin1 MGI:MGI:1933179|Ensembl:ENSMUSG00000038453|Vega:OTTMUSG00000002720 +56014 Olfr70 MGI:MGI:1860079|Ensembl:ENSMUSG00000050215|Vega:OTTMUSG00000007072 +56015 Olfr71 MGI:MGI:1860080|Ensembl:ENSMUSG00000046450|Vega:OTTMUSG00000007073 +56016 Hebp2 MGI:MGI:1860084|Ensembl:ENSMUSG00000019853|Vega:OTTMUSG00000063643 +56017 Slc2a8 MGI:MGI:1860103|Ensembl:ENSMUSG00000026791|Vega:OTTMUSG00000012577 +56018 Stard10 MGI:MGI:1860093|Ensembl:ENSMUSG00000030688|Vega:OTTMUSG00000037676 +56020 D5Buc45 MGI:MGI:1860109 +56021 D5Buc46 MGI:MGI:1860110 +56022 D5Buc47 MGI:MGI:1860111 +56023 D5Buc48 MGI:MGI:1860112 +56024 D5Buc49 MGI:MGI:1860113 +56025 D5Buc50 MGI:MGI:1860114 +56026 D5Buc51 MGI:MGI:1860115 +56027 D5Buc52 MGI:MGI:1860116 +56028 D5Buc53 MGI:MGI:1860117 +56030 Tmem131 MGI:MGI:1927110|Ensembl:ENSMUSG00000026116|Vega:OTTMUSG00000049482 +56031 Ppie MGI:MGI:1917118|Ensembl:ENSMUSG00000028651|Vega:OTTMUSG00000008936 +56032 Nprl2 MGI:MGI:1914482|Ensembl:ENSMUSG00000010057|Vega:OTTMUSG00000050748 +56036 Ccnl2 MGI:MGI:1927119|Ensembl:ENSMUSG00000029068|Vega:OTTMUSG00000010853 +56040 Rplp1 MGI:MGI:1927099|Ensembl:ENSMUSG00000007892|Vega:OTTMUSG00000062531 +56041 Uso1 MGI:MGI:1929095|Ensembl:ENSMUSG00000029407|Vega:OTTMUSG00000055587 +56043 Akr1e1 MGI:MGI:1914758|Ensembl:ENSMUSG00000045410|Vega:OTTMUSG00000027700 +56044 Rala MGI:MGI:1927243|Ensembl:ENSMUSG00000008859|Vega:OTTMUSG00000017001 +56045 Samhd1 MGI:MGI:1927468|Ensembl:ENSMUSG00000027639|Vega:OTTMUSG00000016173 +56046 Uqcc1 MGI:MGI:1929472|Ensembl:ENSMUSG00000005882|Vega:OTTMUSG00000015796 +56047 Msln MGI:MGI:1888992|Ensembl:ENSMUSG00000063011 +56048 Lgals8 MGI:MGI:1928481|Ensembl:ENSMUSG00000057554|Vega:OTTMUSG00000033741 +56050 Cyp39a1 MGI:MGI:1927096|Ensembl:ENSMUSG00000023963 +56055 Gtpbp2 MGI:MGI:1860138|Ensembl:ENSMUSG00000023952|Vega:OTTMUSG00000035552 +56057 Btg4 MGI:MGI:1860140|Ensembl:ENSMUSG00000032056|Vega:OTTMUSG00000063079 +56066 Cxcl11 MGI:MGI:1860203|Ensembl:ENSMUSG00000060183 +56068 Ammecr1 MGI:MGI:1860206|Ensembl:ENSMUSG00000042225|Vega:OTTMUSG00000018861 +56069 Il17b MGI:MGI:1928397|Ensembl:ENSMUSG00000024578 +56070 Tcerg1 MGI:MGI:1926421|Ensembl:ENSMUSG00000024498|Vega:OTTMUSG00000037173 +56072 Lgals12 MGI:MGI:1929094|Ensembl:ENSMUSG00000024972|Vega:OTTMUSG00000034770 +56075 Pdss1 MGI:MGI:1889278|Ensembl:ENSMUSG00000026784|Vega:OTTMUSG00000016619 +56077 Dgke MGI:MGI:1889276|Ensembl:ENSMUSG00000000276|Vega:OTTMUSG00000001312 +56078 Car5b MGI:MGI:1926249|Ensembl:ENSMUSG00000031373|Vega:OTTMUSG00000019511 +56079 Astn2 MGI:MGI:1889277|Ensembl:ENSMUSG00000028373|Vega:OTTMUSG00000000315 +56085 Ubqln1 MGI:MGI:1860276|Ensembl:ENSMUSG00000005312 +56086 Set MGI:MGI:1860267|Ensembl:ENSMUSG00000054766|Vega:OTTMUSG00000016726 +56087 Dnah10 MGI:MGI:1860299|Ensembl:ENSMUSG00000038011|Vega:OTTMUSG00000034141 +56088 Psmg1 MGI:MGI:1860263|Ensembl:ENSMUSG00000022913|Vega:OTTMUSG00000020398 +56089 Ramp3 MGI:MGI:1860292|Ensembl:ENSMUSG00000041046|Vega:OTTMUSG00000005124 +56092 Cts7 MGI:MGI:1860262|Ensembl:ENSMUSG00000021440 +56093 Pfpl MGI:MGI:1860266|Ensembl:ENSMUSG00000040065 +56094 Cts8 MGI:MGI:1860275|Ensembl:ENSMUSG00000057446 +56095 Ftsj3 MGI:MGI:1860295|Ensembl:ENSMUSG00000020706|Vega:OTTMUSG00000003291 +56096 Plac1 MGI:MGI:1926287|Ensembl:ENSMUSG00000061082|Vega:OTTMUSG00000017342 +56149 Grasp MGI:MGI:1860303|Ensembl:ENSMUSG00000000531 +56150 Mad2l1 MGI:MGI:1860374|Ensembl:ENSMUSG00000029910|Vega:OTTMUSG00000023406 +56173 Cldn14 MGI:MGI:1860425|Ensembl:ENSMUSG00000047109|Vega:OTTMUSG00000019962 +56174 Nagk MGI:MGI:1860418|Ensembl:ENSMUSG00000034744|Vega:OTTMUSG00000023757 +56175 Bace2 MGI:MGI:1860440|Ensembl:ENSMUSG00000040605 +56176 Pigp MGI:MGI:1860433|Ensembl:ENSMUSG00000022940|Vega:OTTMUSG00000019883 +56177 Olfm1 MGI:MGI:1860437|Ensembl:ENSMUSG00000026833|Vega:OTTMUSG00000011625 +56183 Nmu MGI:MGI:1860476|Ensembl:ENSMUSG00000029236|Vega:OTTMUSG00000026473 +56184 Msgn1 MGI:MGI:1860483|Ensembl:ENSMUSG00000047002 +56185 Hao2 MGI:MGI:96012|Ensembl:ENSMUSG00000027870|Vega:OTTMUSG00000006827 +56187 Rabggta MGI:MGI:1860443|Ensembl:ENSMUSG00000040472 +56188 Fxyd1 MGI:MGI:1889273|Ensembl:ENSMUSG00000036570|Vega:OTTMUSG00000058047 +56189 Prodh2 MGI:MGI:1929093|Ensembl:ENSMUSG00000036892|Vega:OTTMUSG00000027093 +56190 Rbm38 MGI:MGI:1889294|Ensembl:ENSMUSG00000027510|Vega:OTTMUSG00000016681 +56191 Tro MGI:MGI:1928994|Ensembl:ENSMUSG00000025272|Vega:OTTMUSG00000019171 +56193 Plek MGI:MGI:1860485|Ensembl:ENSMUSG00000020120|Vega:OTTMUSG00000005189 +56194 Prpf40a MGI:MGI:1860512|Ensembl:ENSMUSG00000061136|Vega:OTTMUSG00000012447 +56195 Ptbp2 MGI:MGI:1860489|Ensembl:ENSMUSG00000028134|Vega:OTTMUSG00000054606 +56196 Tdp2 MGI:MGI:1860486|Ensembl:ENSMUSG00000035958|Vega:OTTMUSG00000000605 +56198 Heyl MGI:MGI:1860511|Ensembl:ENSMUSG00000032744|Vega:OTTMUSG00000008972 +56199 Abcb10 MGI:MGI:1860508|Ensembl:ENSMUSG00000031974|Vega:OTTMUSG00000031206 +56200 Ddx21 MGI:MGI:1860494|Ensembl:ENSMUSG00000020075 +56201 T(12;16)1Cje MGI:MGI:1860491 +56202 T(12;16)1Cje MGI:MGI:1860492 +56205 Ensa MGI:MGI:1891189|Ensembl:ENSMUSG00000038619|Vega:OTTMUSG00000053007 +56207 Uchl5 MGI:MGI:1914848|Ensembl:ENSMUSG00000018189|Vega:OTTMUSG00000049324 +56208 Becn1 MGI:MGI:1891828|Ensembl:ENSMUSG00000035086|Vega:OTTMUSG00000002791 +56209 Gde1 MGI:MGI:1891827|Ensembl:ENSMUSG00000033917|Vega:OTTMUSG00000023306 +56210 Rev1 MGI:MGI:1929074|Ensembl:ENSMUSG00000026082|Vega:OTTMUSG00000049485 +56212 Rhog MGI:MGI:1928370|Ensembl:ENSMUSG00000073982|Vega:OTTMUSG00000022529 +56213 Htra1 MGI:MGI:1929076|Ensembl:ENSMUSG00000006205|Vega:OTTMUSG00000031663 +56214 Scamp4 MGI:MGI:1928947|Ensembl:ENSMUSG00000113949 +56215 Acin1 MGI:MGI:1891824|Ensembl:ENSMUSG00000022185|Vega:OTTMUSG00000033084 +56216 Stx1b MGI:MGI:1930705|Ensembl:ENSMUSG00000030806|Vega:OTTMUSG00000031121 +56217 Mpp5 MGI:MGI:1927339|Ensembl:ENSMUSG00000021112 +56218 Patz1 MGI:MGI:1891832|Ensembl:ENSMUSG00000020453|Vega:OTTMUSG00000000758 +56219 Extl1 MGI:MGI:1888742|Ensembl:ENSMUSG00000028838|Vega:OTTMUSG00000010832 +56220 Zfp386 MGI:MGI:1930708|Ensembl:ENSMUSG00000042063|Vega:OTTMUSG00000044392 +56221 Ccl24 MGI:MGI:1928953|Ensembl:ENSMUSG00000004814|Vega:OTTMUSG00000055905 +56222 Cited4 MGI:MGI:1861694|Ensembl:ENSMUSG00000070803|Vega:OTTMUSG00000008811 +56223 Fscn3 MGI:MGI:1890386|Ensembl:ENSMUSG00000029707|Vega:OTTMUSG00000021279 +56224 Tspan5 MGI:MGI:1928096|Ensembl:ENSMUSG00000028152|Vega:OTTMUSG00000029602 +56226 Espn MGI:MGI:1861630|Ensembl:ENSMUSG00000028943|Vega:OTTMUSG00000010307 +56228 Ube2j1 MGI:MGI:1926245|Ensembl:ENSMUSG00000028277|Vega:OTTMUSG00000005008 +56229 Thsd1 MGI:MGI:1929096|Ensembl:ENSMUSG00000031480|Vega:OTTMUSG00000027152 +56233 Hdac7 MGI:MGI:1891835|Ensembl:ENSMUSG00000022475|Vega:OTTMUSG00000029597 +56248 Ak3 MGI:MGI:1860835|Ensembl:ENSMUSG00000024782|Vega:OTTMUSG00000033014 +56249 Actr8 MGI:MGI:1860775|Ensembl:ENSMUSG00000015971 +56258 Hnrnph2 MGI:MGI:1201779|Ensembl:ENSMUSG00000045427|Vega:OTTMUSG00000019387 +56264 Cpxm1 MGI:MGI:1934569|Ensembl:ENSMUSG00000027408|Vega:OTTMUSG00000015522 +56273 Pex14 MGI:MGI:1927868|Ensembl:ENSMUSG00000028975|Vega:OTTMUSG00000010943 +56274 Stk3 MGI:MGI:1928487|Ensembl:ENSMUSG00000022329|Vega:OTTMUSG00000032792 +56275 Rbm14 MGI:MGI:1929092|Ensembl:ENSMUSG00000006456|Vega:OTTMUSG00000042312 +56277 Tmem45a MGI:MGI:1913122|Ensembl:ENSMUSG00000022754|Vega:OTTMUSG00000026973 +56278 Gkap1 MGI:MGI:1891694|Ensembl:ENSMUSG00000021552 +56279 Fam69b MGI:MGI:1927576|Ensembl:ENSMUSG00000036186|Vega:OTTMUSG00000011585 +56280 Mrpl37 MGI:MGI:1926268|Ensembl:ENSMUSG00000028622|Vega:OTTMUSG00000008412 +56282 Mrpl12 MGI:MGI:1926273|Ensembl:ENSMUSG00000039640|Vega:OTTMUSG00000004268 +56284 Mrpl19 MGI:MGI:1926274|Ensembl:ENSMUSG00000030045|Vega:OTTMUSG00000023534 +56289 Rassf1 MGI:MGI:1928386|Ensembl:ENSMUSG00000010067|Vega:OTTMUSG00000030554 +56291 Styx MGI:MGI:1891150|Ensembl:ENSMUSG00000053205 +56292 Naa10 MGI:MGI:1915255|Ensembl:ENSMUSG00000031388|Vega:OTTMUSG00000017704 +56293 Slc35g3 MGI:MGI:1927128|Ensembl:ENSMUSG00000018776|Vega:OTTMUSG00000005994 +56294 Ptpn9 MGI:MGI:1928376|Ensembl:ENSMUSG00000032290|Vega:OTTMUSG00000063137 +56295 Higd1a MGI:MGI:1930666|Ensembl:ENSMUSG00000038412|Vega:OTTMUSG00000062673 +56296 Dmrtb1 MGI:MGI:1927125|Ensembl:ENSMUSG00000028610|Vega:OTTMUSG00000008961 +56297 Arl6 MGI:MGI:1927136|Ensembl:ENSMUSG00000022722|Vega:OTTMUSG00000026308 +56298 Atl2 MGI:MGI:1929492|Ensembl:ENSMUSG00000059811 +56299 Fkbpl MGI:MGI:1932127|Ensembl:ENSMUSG00000033739|Vega:OTTMUSG00000037080 +56304 Ce9 - +56305 Pitpnb MGI:MGI:1927542|Ensembl:ENSMUSG00000050017|Vega:OTTMUSG00000054235 +56306 Fam60a MGI:MGI:1929091|Ensembl:ENSMUSG00000039985|Vega:OTTMUSG00000024045 +56307 Metap2 MGI:MGI:1929701|Ensembl:ENSMUSG00000036112|Vega:OTTMUSG00000042658 +56309 Mycbp MGI:MGI:1891750|Ensembl:ENSMUSG00000028647|Vega:OTTMUSG00000008990 +56310 Gps2 MGI:MGI:1891751|Ensembl:ENSMUSG00000023170|Vega:OTTMUSG00000006026 +56312 Nupr1 MGI:MGI:1891834|Ensembl:ENSMUSG00000030717|Vega:OTTMUSG00000025271 +56314 Zfp113 MGI:MGI:1929116|Ensembl:ENSMUSG00000037007|Vega:OTTMUSG00000022637 +56315 Rhcg MGI:MGI:1888517|Ensembl:ENSMUSG00000030549|Vega:OTTMUSG00000025008 +56316 Ggcx MGI:MGI:1927655|Ensembl:ENSMUSG00000053460|Vega:OTTMUSG00000026391 +56317 Anapc7 MGI:MGI:1929711|Ensembl:ENSMUSG00000029466|Vega:OTTMUSG00000026723 +56318 Acpp MGI:MGI:1928480|Ensembl:ENSMUSG00000032561|Vega:OTTMUSG00000024988 +56320 Dbn1 MGI:MGI:1931838|Ensembl:ENSMUSG00000034675|Vega:OTTMUSG00000017050 +56321 Aatf MGI:MGI:1929608|Ensembl:ENSMUSG00000018697|Vega:OTTMUSG00000000987 +56322 Timm22 MGI:MGI:1929742|Ensembl:ENSMUSG00000020843|Vega:OTTMUSG00000006231 +56323 Dnajb5 MGI:MGI:1930018|Ensembl:ENSMUSG00000036052|Vega:OTTMUSG00000006629 +56324 Stam2 MGI:MGI:1929100|Ensembl:ENSMUSG00000055371|Vega:OTTMUSG00000012637 +56325 Abcb9 MGI:MGI:1861729|Ensembl:ENSMUSG00000029408|Vega:OTTMUSG00000028882 +56327 Arl2 MGI:MGI:1928393|Ensembl:ENSMUSG00000024944|Vega:OTTMUSG00000018610 +56330 Pdcd5 MGI:MGI:1913538|Ensembl:ENSMUSG00000030417|Vega:OTTMUSG00000029735 +56332 Amotl2 MGI:MGI:1929286|Ensembl:ENSMUSG00000032531|Vega:OTTMUSG00000033309 +56334 Tmed2 MGI:MGI:1929269|Ensembl:ENSMUSG00000029390|Vega:OTTMUSG00000024462 +56335 Mettl3 MGI:MGI:1927165|Ensembl:ENSMUSG00000022160|Vega:OTTMUSG00000023342 +56336 B4galt5 MGI:MGI:1927169|Ensembl:ENSMUSG00000017929|Vega:OTTMUSG00000001180 +56338 Txnip MGI:MGI:1889549|Ensembl:ENSMUSG00000038393|Vega:OTTMUSG00000021271 +56347 Eif3c MGI:MGI:1926966|Ensembl:ENSMUSG00000030738|Vega:OTTMUSG00000042475 +56348 Hsd17b12 MGI:MGI:1926967|Ensembl:ENSMUSG00000027195|Vega:OTTMUSG00000015008 +56349 Net1 MGI:MGI:1927138|Ensembl:ENSMUSG00000021215 +56350 Arl3 MGI:MGI:1929699|Ensembl:ENSMUSG00000025035 +56351 Ptges3 MGI:MGI:1929282|Ensembl:ENSMUSG00000071072|Vega:OTTMUSG00000020944 +56353 Rybp MGI:MGI:1929059|Ensembl:ENSMUSG00000072872|Vega:OTTMUSG00000056686 +56354 Dnajc7 MGI:MGI:1928373|Ensembl:ENSMUSG00000014195|Vega:OTTMUSG00000002027 +56356 Gltp MGI:MGI:1929253|Ensembl:ENSMUSG00000011884|Vega:OTTMUSG00000014502 +56357 Ivd MGI:MGI:1929242|Ensembl:ENSMUSG00000027332|Vega:OTTMUSG00000014828 +56358 Copz2 MGI:MGI:1929008|Ensembl:ENSMUSG00000018672|Vega:OTTMUSG00000001637 +56360 Acot9 MGI:MGI:1928939|Ensembl:ENSMUSG00000025287|Vega:OTTMUSG00000019354 +56361 Pus1 MGI:MGI:1929237|Ensembl:ENSMUSG00000029507|Vega:OTTMUSG00000023691 +56362 Sult1b1 MGI:MGI:2136282|Ensembl:ENSMUSG00000029269|Vega:OTTMUSG00000026691 +56363 Tmeff2 MGI:MGI:1861735|Ensembl:ENSMUSG00000026109|Vega:OTTMUSG00000022395 +56364 Zmym3 MGI:MGI:1927231|Ensembl:ENSMUSG00000031310|Vega:OTTMUSG00000018207 +56365 Clcnkb MGI:MGI:1930643|Ensembl:ENSMUSG00000006216|Vega:OTTMUSG00000010299 +56367 Scoc MGI:MGI:1927654|Ensembl:ENSMUSG00000063253|Vega:OTTMUSG00000061552 +56368 Cyb561d2 MGI:MGI:1929280|Ensembl:ENSMUSG00000037190|Vega:OTTMUSG00000050780 +56369 Apip MGI:MGI:1926788|Ensembl:ENSMUSG00000010911|Vega:OTTMUSG00000014842 +56370 Tagln3 MGI:MGI:1926784|Ensembl:ENSMUSG00000022658|Vega:OTTMUSG00000026844 +56371 Fzr1 MGI:MGI:1926790|Ensembl:ENSMUSG00000020235|Vega:OTTMUSG00000030386 +56372 1110004F10Rik MGI:MGI:1929274|Ensembl:ENSMUSG00000030663|Vega:OTTMUSG00000023018 +56373 Cpb2 MGI:MGI:1891837|Ensembl:ENSMUSG00000021999 +56374 Tmem59 MGI:MGI:1929278|Ensembl:ENSMUSG00000028618|Vega:OTTMUSG00000008472 +56375 B4galt4 MGI:MGI:1928387|Ensembl:ENSMUSG00000022793|Vega:OTTMUSG00000023966 +56376 Pdlim5 MGI:MGI:1927489|Ensembl:ENSMUSG00000028273|Vega:OTTMUSG00000053833 +56378 Arpc3 MGI:MGI:1928375|Ensembl:ENSMUSG00000029465|Vega:OTTMUSG00000016282 +56379 Kcnj1 MGI:MGI:1927248|Ensembl:ENSMUSG00000041248|Vega:OTTMUSG00000062897 +56380 Arid3b MGI:MGI:1930768|Ensembl:ENSMUSG00000004661|Vega:OTTMUSG00000036791 +56381 Spen MGI:MGI:1891706|Ensembl:ENSMUSG00000040761|Vega:OTTMUSG00000010345 +56382 Rab9 MGI:MGI:1890695|Ensembl:ENSMUSG00000079316|Vega:OTTMUSG00000019544 +56384 Letm1 MGI:MGI:1932557|Ensembl:ENSMUSG00000005299|Vega:OTTMUSG00000021523 +56386 B4galt6 MGI:MGI:1928380|Ensembl:ENSMUSG00000056124 +56388 Cyp3a25 MGI:MGI:1930638|Ensembl:ENSMUSG00000029630|Vega:OTTMUSG00000025089 +56389 Stx5a MGI:MGI:1928483|Ensembl:ENSMUSG00000010110|Vega:OTTMUSG00000039850 +56390 Sssca1 MGI:MGI:1913482|Ensembl:ENSMUSG00000079478|Vega:OTTMUSG00000035065 +56392 Shoc2 MGI:MGI:1927197|Ensembl:ENSMUSG00000024976 +56395 Tmem115 MGI:MGI:1930765|Ensembl:ENSMUSG00000010045|Vega:OTTMUSG00000050747 +56397 Morf4l2 MGI:MGI:1927167|Ensembl:ENSMUSG00000031422|Vega:OTTMUSG00000018725 +56398 Chp1 MGI:MGI:1927185|Ensembl:ENSMUSG00000014077|Vega:OTTMUSG00000015945 +56399 Akap8 MGI:MGI:1928488|Ensembl:ENSMUSG00000024045 +56401 P3h1 MGI:MGI:1888921|Ensembl:ENSMUSG00000028641|Vega:OTTMUSG00000009225 +56403 Syncrip MGI:MGI:1891690|Ensembl:ENSMUSG00000032423|Vega:OTTMUSG00000037703 +56404 Trip4 MGI:MGI:1928469|Ensembl:ENSMUSG00000032386|Vega:OTTMUSG00000029847 +56405 Dusp14 MGI:MGI:1927168|Ensembl:ENSMUSG00000018648|Vega:OTTMUSG00000000968 +56406 Ncoa6 MGI:MGI:1929915|Ensembl:ENSMUSG00000038369|Vega:OTTMUSG00000016062 +56407 Trpc4ap MGI:MGI:1930751|Ensembl:ENSMUSG00000038324|Vega:OTTMUSG00000016133 +56409 Nudt3 MGI:MGI:1928484|Ensembl:ENSMUSG00000024213|Vega:OTTMUSG00000018655 +56410 Cbln3 MGI:MGI:1889286|Ensembl:ENSMUSG00000040380 +56412 Noa1 MGI:MGI:1914306|Ensembl:ENSMUSG00000036285|Vega:OTTMUSG00000026773 +56417 Adar MGI:MGI:1889575|Ensembl:ENSMUSG00000027951|Vega:OTTMUSG00000020280 +56418 Ykt6 MGI:MGI:1927550|Ensembl:ENSMUSG00000002741|Vega:OTTMUSG00000005103 +56419 Diaph3 MGI:MGI:1927222|Ensembl:ENSMUSG00000022021 +56420 Ppp4c MGI:MGI:1891763|Ensembl:ENSMUSG00000030697|Vega:OTTMUSG00000058355 +56421 Pfkp MGI:MGI:1891833|Ensembl:ENSMUSG00000021196|Vega:OTTMUSG00000033856 +56422 Hbs1l MGI:MGI:1891704|Ensembl:ENSMUSG00000019977 +56424 Stub1 MGI:MGI:1891731|Ensembl:ENSMUSG00000039615 +56426 Pdcd10 MGI:MGI:1928396|Ensembl:ENSMUSG00000027835|Vega:OTTMUSG00000031048 +56427 Tubd1 MGI:MGI:1891826|Ensembl:ENSMUSG00000020513|Vega:OTTMUSG00000001200 +56428 Mtch2 MGI:MGI:1929260|Ensembl:ENSMUSG00000027282|Vega:OTTMUSG00000014305 +56429 Dpt MGI:MGI:1928392|Ensembl:ENSMUSG00000026574|Vega:OTTMUSG00000049869 +56430 Clip1 MGI:MGI:1928401|Ensembl:ENSMUSG00000049550|Vega:OTTMUSG00000025900 +56431 Dstn MGI:MGI:1929270|Ensembl:ENSMUSG00000015932|Vega:OTTMUSG00000003226 +56433 Vps29 MGI:MGI:1928344|Ensembl:ENSMUSG00000029462|Vega:OTTMUSG00000026702 +56434 Tspan3 MGI:MGI:1928098|Ensembl:ENSMUSG00000032324|Vega:OTTMUSG00000063117 +56436 Adrm1 MGI:MGI:1929289|Ensembl:ENSMUSG00000039041|Vega:OTTMUSG00000016265 +56437 Rrad MGI:MGI:1930943|Ensembl:ENSMUSG00000031880|Vega:OTTMUSG00000061963 +56438 Rbx1 MGI:MGI:1891829|Ensembl:ENSMUSG00000022400 +56440 Snx1 MGI:MGI:1928395|Ensembl:ENSMUSG00000032382|Vega:OTTMUSG00000031789 +56441 Nat6 MGI:MGI:1888902|Ensembl:ENSMUSG00000079334|Vega:OTTMUSG00000028836 +56442 Serinc1 MGI:MGI:1926228|Ensembl:ENSMUSG00000019877|Vega:OTTMUSG00000035404 +56443 Arpc1a MGI:MGI:1928896|Ensembl:ENSMUSG00000029621|Vega:OTTMUSG00000022945 +56444 Actr10 MGI:MGI:1891654|Ensembl:ENSMUSG00000021076 +56445 Dnaja2 MGI:MGI:1931882|Ensembl:ENSMUSG00000031701|Vega:OTTMUSG00000061420 +56447 Copz1 MGI:MGI:1929063|Ensembl:ENSMUSG00000060992 +56448 Cyp2d22 MGI:MGI:1929474|Ensembl:ENSMUSG00000061740 +56449 Ybx3 MGI:MGI:2137670|Ensembl:ENSMUSG00000030189|Vega:OTTMUSG00000056779 +56451 Suclg1 MGI:MGI:1927234|Ensembl:ENSMUSG00000052738|Vega:OTTMUSG00000023469 +56452 Orc6 MGI:MGI:1929285|Ensembl:ENSMUSG00000031697|Vega:OTTMUSG00000061417 +56453 Mbtps1 MGI:MGI:1927235|Ensembl:ENSMUSG00000031835|Vega:OTTMUSG00000061639 +56454 Aldh18a1 MGI:MGI:1888908|Ensembl:ENSMUSG00000025007|Vega:OTTMUSG00000026289 +56455 Dynll1 MGI:MGI:1861457|Ensembl:ENSMUSG00000009013|Vega:OTTMUSG00000014648 +56456 Actl6a MGI:MGI:1861453|Ensembl:ENSMUSG00000027671|Vega:OTTMUSG00000021872 +56457 Clptm1 MGI:MGI:1927155|Ensembl:ENSMUSG00000002981|Vega:OTTMUSG00000059268 +56458 Foxo1 MGI:MGI:1890077|Ensembl:ENSMUSG00000044167|Vega:OTTMUSG00000021250 +56459 Sae1 MGI:MGI:1929264|Ensembl:ENSMUSG00000052833|Vega:OTTMUSG00000060584 +56460 Pkp3 MGI:MGI:1891830|Ensembl:ENSMUSG00000054065|Vega:OTTMUSG00000028871 +56461 Kcnip3 MGI:MGI:1929258|Ensembl:ENSMUSG00000079056|Vega:OTTMUSG00000016030 +56462 Mtch1 MGI:MGI:1929261|Ensembl:ENSMUSG00000024012|Vega:OTTMUSG00000028973 +56463 Snd1 MGI:MGI:1929266|Ensembl:ENSMUSG00000001424|Vega:OTTMUSG00000035791 +56464 Ctsf MGI:MGI:1861434|Ensembl:ENSMUSG00000083282 +56468 Socs5 MGI:MGI:2385459|Ensembl:ENSMUSG00000037104 +56469 Pias1 MGI:MGI:1913125|Ensembl:ENSMUSG00000032405|Vega:OTTMUSG00000062567 +56470 Rgs19 MGI:MGI:1915153|Ensembl:ENSMUSG00000002458|Vega:OTTMUSG00000016814 +56471 Stmn4 MGI:MGI:1931224|Ensembl:ENSMUSG00000022044|Vega:OTTMUSG00000027814 +56473 Fads2 MGI:MGI:1930079|Ensembl:ENSMUSG00000024665 +56480 Tbk1 MGI:MGI:1929658|Ensembl:ENSMUSG00000020115 +56484 Foxo3 MGI:MGI:1890081|Ensembl:ENSMUSG00000048756|Vega:OTTMUSG00000020929 +56485 Slc2a5 MGI:MGI:1928369|Ensembl:ENSMUSG00000028976|Vega:OTTMUSG00000010389 +56486 Gabarap MGI:MGI:1861742|Ensembl:ENSMUSG00000018567|Vega:OTTMUSG00000006020 +56488 Nxt1 MGI:MGI:1929619|Ensembl:ENSMUSG00000036992|Vega:OTTMUSG00000015709 +56489 Ikbke MGI:MGI:1929612|Ensembl:ENSMUSG00000042349|Vega:OTTMUSG00000034782 +56490 Zbtb20 MGI:MGI:1929213|Ensembl:ENSMUSG00000022708|Vega:OTTMUSG00000025618 +56491 Vapb MGI:MGI:1928744|Ensembl:ENSMUSG00000054455|Vega:OTTMUSG00000016375 +56492 Cldn18 MGI:MGI:1929209|Ensembl:ENSMUSG00000032473|Vega:OTTMUSG00000028913 +56494 Gosr2 MGI:MGI:1927204|Ensembl:ENSMUSG00000020946|Vega:OTTMUSG00000003021 +56495 Asna1 MGI:MGI:1928379|Ensembl:ENSMUSG00000052456|Vega:OTTMUSG00000061400 +56496 Tspan6 MGI:MGI:1926264|Ensembl:ENSMUSG00000067377|Vega:OTTMUSG00000018712 +56501 Elf4 MGI:MGI:1928377|Ensembl:ENSMUSG00000031103|Vega:OTTMUSG00000017543 +56503 Ankrd49 MGI:MGI:1930842|Ensembl:ENSMUSG00000031931|Vega:OTTMUSG00000062711 +56504 Srpk3 MGI:MGI:1891338|Ensembl:ENSMUSG00000002007|Vega:OTTMUSG00000017656 +56505 Ruvbl1 MGI:MGI:1928760|Ensembl:ENSMUSG00000030079|Vega:OTTMUSG00000023968 +56506 Cib2 MGI:MGI:1929293|Ensembl:ENSMUSG00000037493|Vega:OTTMUSG00000030276 +56508 Rapgef4 MGI:MGI:1917723|Ensembl:ENSMUSG00000049044|Vega:OTTMUSG00000013137 +56513 Pard6a MGI:MGI:1927223|Ensembl:ENSMUSG00000005699|Vega:OTTMUSG00000062054 +56515 Rnf138 MGI:MGI:1929211|Ensembl:ENSMUSG00000024317 +56516 Rbms2 MGI:MGI:1861776|Ensembl:ENSMUSG00000040043 +56517 Slc22a21 MGI:MGI:1929481|Ensembl:ENSMUSG00000063652|Vega:OTTMUSG00000005655 +56519 Defb4 MGI:MGI:1927667|Ensembl:ENSMUSG00000059230|Vega:OTTMUSG00000020596 +56520 Nme4 MGI:MGI:1931148|Ensembl:ENSMUSG00000024177|Vega:OTTMUSG00000026500 +56522 Papolb MGI:MGI:1932115|Ensembl:ENSMUSG00000074817|Vega:OTTMUSG00000026090 +56523 Pmfbp1 MGI:MGI:1930136|Ensembl:ENSMUSG00000031727|Vega:OTTMUSG00000061916 +56524 Mpp6 MGI:MGI:1927340|Ensembl:ENSMUSG00000038388|Vega:OTTMUSG00000035974 +56525 Zfp235 MGI:MGI:1929117|Ensembl:ENSMUSG00000047603|Vega:OTTMUSG00000058066 +56526 Sept6 MGI:MGI:1888939|Ensembl:ENSMUSG00000050379|Vega:OTTMUSG00000017110 +56527 Mast1 MGI:MGI:1861901|Ensembl:ENSMUSG00000053693|Vega:OTTMUSG00000029992 +56529 Sec11a MGI:MGI:1929464|Ensembl:ENSMUSG00000025724|Vega:OTTMUSG00000031331 +56530 Cnpy2 MGI:MGI:1928477|Ensembl:ENSMUSG00000025381 +56531 Ylpm1 MGI:MGI:1926195|Ensembl:ENSMUSG00000021244|Vega:OTTMUSG00000036264 +56532 Ripk3 MGI:MGI:2154952|Ensembl:ENSMUSG00000022221 +56533 Rgs17 MGI:MGI:1927469|Ensembl:ENSMUSG00000019775|Vega:OTTMUSG00000027502 +56534 Hspb3 MGI:MGI:1928479|Ensembl:ENSMUSG00000051456 +56535 Pex3 MGI:MGI:1929646|Ensembl:ENSMUSG00000019809|Vega:OTTMUSG00000020905 +56538 Klk11 MGI:MGI:1929977|Ensembl:ENSMUSG00000067616|Vega:OTTMUSG00000058308 +56541 Habp4 MGI:MGI:1891713|Ensembl:ENSMUSG00000021476 +56542 Ick MGI:MGI:1934157|Ensembl:ENSMUSG00000009828|Vega:OTTMUSG00000031751 +56543 Kcnd3 MGI:MGI:1928743|Ensembl:ENSMUSG00000040896|Vega:OTTMUSG00000026532 +56544 Vmn2r1 MGI:MGI:3645892|Ensembl:ENSMUSG00000027824|Vega:OTTMUSG00000039823 +56546 Sec1 MGI:MGI:1928893|Ensembl:ENSMUSG00000040364|Vega:OTTMUSG00000033563 +56550 Ube2d2a MGI:MGI:1930715|Ensembl:ENSMUSG00000091896 +56551 Txn2 MGI:MGI:1929468|Ensembl:ENSMUSG00000005354|Vega:OTTMUSG00000020980 +56552 Vmn2r26 MGI:MGI:2678394|Ensembl:ENSMUSG00000096630|Vega:OTTMUSG00000027049 +56554 Raet1d MGI:MGI:1861032|Ensembl:ENSMUSG00000078452|Vega:OTTMUSG00000033466 +56557 D6Ott8 MGI:MGI:1860946 +56558 D6Ott11 MGI:MGI:1860947 +56559 D6Ott22 MGI:MGI:1860948 +56560 D6Ott32 MGI:MGI:1860949 +56561 D6Ott112 MGI:MGI:1860950 +56562 D6Ott115 MGI:MGI:1860951 +56563 D6Ott113 MGI:MGI:1860952 +56565 52A6L MGI:MGI:1860940 +56566 8k10T7 MGI:MGI:1860908 +56567 14c5T7 MGI:MGI:1860910 +56568 200H7R MGI:MGI:1860926 +56570 14c5Sp6 MGI:MGI:1860909 +56571 65M5F9R MGI:MGI:1860912 +56572 87M6F7R MGI:MGI:1860914 +56573 102g4T7 MGI:MGI:1860915 +56574 109F12R MGI:MGI:1860916 +56575 156l3T7 MGI:MGI:1860920 +56576 446o7T7 MGI:MGI:1860936 +56577 43f9Sp6 MGI:MGI:1860939 +56581 66M4E12R MGI:MGI:1860913 +56582 116m19T7 MGI:MGI:1860918 +56583 137h23T7 MGI:MGI:1860919 +56584 170n17T7 MGI:MGI:1860922 +56585 236m20T7 MGI:MGI:1860929 +56586 240c11T7 MGI:MGI:1860931 +56588 242D11L2 MGI:MGI:1860942 +56589 282h8Sp6 MGI:MGI:1860943 +56590 301l2Sp6 MGI:MGI:1860935 +56591 116m19Sp6 MGI:MGI:1860917 +56592 170n17Sp6 MGI:MGI:1860921 +56593 174g24Sp6 MGI:MGI:1860923 +56594 177i23Sp6 MGI:MGI:1860924 +56595 184a16Sp6 MGI:MGI:1860925 +56596 204d20Sp6 MGI:MGI:1860927 +56597 236m20Sp6 MGI:MGI:1860928 +56598 240c11Sp6 MGI:MGI:1860930 +56599 247d24Sp6 MGI:MGI:1860932 +56600 291h24Sp6 MGI:MGI:1860934 +56601 463o20Sp6 MGI:MGI:1860937 +56607 D5Mgc1 MGI:MGI:1861140 +56608 D6Mgc2 MGI:MGI:1861141 +56609 D7Mgc1 MGI:MGI:1861142 +56610 D12Mgc1 MGI:MGI:1861139 +56612 Pfdn5 MGI:MGI:1928753|Ensembl:ENSMUSG00000001289|Vega:OTTMUSG00000035798 +56613 Rps6ka4 MGI:MGI:1930076|Ensembl:ENSMUSG00000024952 +56615 Mgst1 MGI:MGI:1913850|Ensembl:ENSMUSG00000008540|Vega:OTTMUSG00000027063 +56619 Clec4e MGI:MGI:1861232|Ensembl:ENSMUSG00000030142|Vega:OTTMUSG00000040025 +56620 Clec4n MGI:MGI:1861231|Ensembl:ENSMUSG00000023349|Vega:OTTMUSG00000027044 +56622 Adam21 MGI:MGI:1861229|Ensembl:ENSMUSG00000008438|Vega:OTTMUSG00000035333 +56626 Poll MGI:MGI:1889000|Ensembl:ENSMUSG00000025218 +56629 Dnase2b MGI:MGI:1913283|Ensembl:ENSMUSG00000028185|Vega:OTTMUSG00000022298 +56631 Trim17 MGI:MGI:1861440|Ensembl:ENSMUSG00000036964|Vega:OTTMUSG00000005771 +56632 Sphk2 MGI:MGI:1861380|Ensembl:ENSMUSG00000057342|Vega:OTTMUSG00000023186 +56635 Prl2a1 MGI:MGI:1861446|Ensembl:ENSMUSG00000022886|Vega:OTTMUSG00000000649 +56636 Fgf21 MGI:MGI:1861377|Ensembl:ENSMUSG00000030827|Vega:OTTMUSG00000058294 +56637 Gsk3b MGI:MGI:1861437|Ensembl:ENSMUSG00000022812|Vega:OTTMUSG00000016276 +56640 Klk4 MGI:MGI:1861379|Ensembl:ENSMUSG00000006948|Vega:OTTMUSG00000058315 +56642 Ankrd2 MGI:MGI:1861447|Ensembl:ENSMUSG00000025172 +56643 Slc15a1 MGI:MGI:1861376|Ensembl:ENSMUSG00000025557 +56644 Clec7a MGI:MGI:1861431|Ensembl:ENSMUSG00000079293|Vega:OTTMUSG00000042656 +56645 Tcea1-ps1 MGI:MGI:1861432 +56690 Mlycd MGI:MGI:1928485|Ensembl:ENSMUSG00000074064|Vega:OTTMUSG00000026334 +56691 Dnajb8 MGI:MGI:1922801|Ensembl:ENSMUSG00000048206|Vega:OTTMUSG00000022405 +56692 Lamtor3 MGI:MGI:1929467|Ensembl:ENSMUSG00000091512|Vega:OTTMUSG00000052741 +56693 Crtap MGI:MGI:1891221|Ensembl:ENSMUSG00000032431|Vega:OTTMUSG00000033583 +56695 Pnkd MGI:MGI:1930773|Ensembl:ENSMUSG00000026179|Vega:OTTMUSG00000021729 +56696 Gpr132 MGI:MGI:1890220|Ensembl:ENSMUSG00000021298 +56697 Akap10 MGI:MGI:1890218|Ensembl:ENSMUSG00000047804|Vega:OTTMUSG00000005847 +56698 Phax MGI:MGI:1891839|Ensembl:ENSMUSG00000008301|Vega:OTTMUSG00000033191 +56699 Cdc42ep4 MGI:MGI:1929760|Ensembl:ENSMUSG00000041598|Vega:OTTMUSG00000003850 +56700 Glmp MGI:MGI:1913318|Ensembl:ENSMUSG00000001418|Vega:OTTMUSG00000027147 +56702 Hist1h1b MGI:MGI:1861461|Ensembl:ENSMUSG00000058773|Vega:OTTMUSG00000000730 +56703 Pigo MGI:MGI:1861452|Ensembl:ENSMUSG00000028454|Vega:OTTMUSG00000006691 +56705 Ranbp9 MGI:MGI:1928741|Ensembl:ENSMUSG00000038546 +56706 Ccnl1 MGI:MGI:1922664|Ensembl:ENSMUSG00000027829|Vega:OTTMUSG00000029434 +56707 Zfp111 MGI:MGI:1929114|Ensembl:ENSMUSG00000087598|Vega:OTTMUSG00000029438 +56708 Clcf1 MGI:MGI:1930088|Ensembl:ENSMUSG00000040663|Vega:OTTMUSG00000028319 +56709 Dnajb12 MGI:MGI:1931881|Ensembl:ENSMUSG00000020109|Vega:OTTMUSG00000034094 +56710 Brinp1 MGI:MGI:1928478|Ensembl:ENSMUSG00000028351|Vega:OTTMUSG00000000310 +56711 Plag1 MGI:MGI:1891916|Ensembl:ENSMUSG00000003282|Vega:OTTMUSG00000004402 +56715 Rabgef1 MGI:MGI:1929459|Ensembl:ENSMUSG00000025340|Vega:OTTMUSG00000027862 +56716 Mlst8 MGI:MGI:1929514|Ensembl:ENSMUSG00000024142 +56717 Mtor MGI:MGI:1928394|Ensembl:ENSMUSG00000028991|Vega:OTTMUSG00000010950 +56720 Tdo2 MGI:MGI:1928486|Ensembl:ENSMUSG00000028011|Vega:OTTMUSG00000023136 +56722 Litaf MGI:MGI:1929512|Ensembl:ENSMUSG00000022500|Vega:OTTMUSG00000026365 +56724 Cript MGI:MGI:1929655|Ensembl:ENSMUSG00000024146|Vega:OTTMUSG00000028497 +56726 Sh3bgrl MGI:MGI:1930849|Ensembl:ENSMUSG00000031246|Vega:OTTMUSG00000018335 +56727 Miox MGI:MGI:1891725|Ensembl:ENSMUSG00000022613|Vega:OTTMUSG00000034719 +56734 Tulp2 MGI:MGI:1861600|Ensembl:ENSMUSG00000023467|Vega:OTTMUSG00000024071 +56735 Krt71 MGI:MGI:1861586|Ensembl:ENSMUSG00000051879|Vega:OTTMUSG00000027989 +56736 Rnf14 MGI:MGI:1929668|Ensembl:ENSMUSG00000060450 +56737 Alg2 MGI:MGI:1914731|Ensembl:ENSMUSG00000039740|Vega:OTTMUSG00000006801 +56738 Mocs1 MGI:MGI:1928904|Ensembl:ENSMUSG00000064120|Vega:OTTMUSG00000036925 +56739 Rec8 MGI:MGI:1929645|Ensembl:ENSMUSG00000002324|Vega:OTTMUSG00000027876 +56741 Igdcc4 MGI:MGI:1858497|Ensembl:ENSMUSG00000032816|Vega:OTTMUSG00000062619 +56742 Psrc1 MGI:MGI:1913099|Ensembl:ENSMUSG00000068744|Vega:OTTMUSG00000007307 +56743 Lat2 MGI:MGI:1926479|Ensembl:ENSMUSG00000040751|Vega:OTTMUSG00000055759 +56744 Pf4 MGI:MGI:1888711|Ensembl:ENSMUSG00000029373|Vega:OTTMUSG00000055505 +56745 C1qtnf1 MGI:MGI:1919254|Ensembl:ENSMUSG00000017446|Vega:OTTMUSG00000003980 +56746 Tex101 MGI:MGI:1930791|Ensembl:ENSMUSG00000062773|Vega:OTTMUSG00000058229 +56747 Sez6l MGI:MGI:1935121|Ensembl:ENSMUSG00000058153|Vega:OTTMUSG00000054331 +56748 Nfu1 MGI:MGI:1913290|Ensembl:ENSMUSG00000029993|Vega:OTTMUSG00000029692 +56749 Dhodh MGI:MGI:1928378|Ensembl:ENSMUSG00000031730|Vega:OTTMUSG00000032870 +56752 Aldh9a1 MGI:MGI:1861622|Ensembl:ENSMUSG00000026687|Vega:OTTMUSG00000050636 +56753 Tacstd2 MGI:MGI:1861606|Ensembl:ENSMUSG00000051397|Vega:OTTMUSG00000052511 +56758 Mbnl1 MGI:MGI:1928482|Ensembl:ENSMUSG00000027763|Vega:OTTMUSG00000051966 +56760 Clec1b MGI:MGI:1913287|Ensembl:ENSMUSG00000030159|Vega:OTTMUSG00000027001 +56771 Med20 MGI:MGI:1929648|Ensembl:ENSMUSG00000092558|Vega:OTTMUSG00000037165 +56772 Mllt11 MGI:MGI:1929671|Ensembl:ENSMUSG00000053192|Vega:OTTMUSG00000021997 +56773 Chst5 MGI:MGI:1931825|Ensembl:ENSMUSG00000031952|Vega:OTTMUSG00000061805 +56774 Slc6a14 MGI:MGI:1890216|Ensembl:ENSMUSG00000031089|Vega:OTTMUSG00000017212 +56784 Ralgapa1 MGI:MGI:1931050|Ensembl:ENSMUSG00000021027 +56786 Tmem9b MGI:MGI:1915254|Ensembl:ENSMUSG00000031021|Vega:OTTMUSG00000027355 +56787 Ascl3 MGI:MGI:1928820|Ensembl:ENSMUSG00000035951|Vega:OTTMUSG00000060127 +56788 Scube2 MGI:MGI:1928765|Ensembl:ENSMUSG00000007279|Vega:OTTMUSG00000021272 +56790 Supt20 MGI:MGI:1929651|Ensembl:ENSMUSG00000027751|Vega:OTTMUSG00000053973 +56791 Ube2l6 MGI:MGI:1914500|Ensembl:ENSMUSG00000027078|Vega:OTTMUSG00000013725 +56792 Stap1 MGI:MGI:1926193|Ensembl:ENSMUSG00000029254|Vega:OTTMUSG00000022745 +56794 Hacl1 MGI:MGI:1929657|Ensembl:ENSMUSG00000021884|Vega:OTTMUSG00000024573 +56795 Arl10 MGI:MGI:1930788|Ensembl:ENSMUSG00000025870|Vega:OTTMUSG00000032683 +56802 Nespas MGI:MGI:1861674|Ensembl:ENSMUSG00000086537 +56805 Zbtb33 MGI:MGI:1927290|Ensembl:ENSMUSG00000048047|Vega:OTTMUSG00000017200 +56807 Scamp5 MGI:MGI:1928948|Ensembl:ENSMUSG00000040722|Vega:OTTMUSG00000063177 +56808 Cacna2d2 MGI:MGI:1929813|Ensembl:ENSMUSG00000010066|Vega:OTTMUSG00000036844 +56809 Gmeb1 MGI:MGI:2135604|Ensembl:ENSMUSG00000028901|Vega:OTTMUSG00000011110 +56811 Dkk2 MGI:MGI:1890663|Ensembl:ENSMUSG00000028031|Vega:OTTMUSG00000054905 +56812 Dnajb2 MGI:MGI:1928739|Ensembl:ENSMUSG00000026203|Vega:OTTMUSG00000048595 +56835 Ctsr MGI:MGI:1861723|Ensembl:ENSMUSG00000055679 +56838 Ccl28 MGI:MGI:1861731|Ensembl:ENSMUSG00000074715 +56839 Lgi1 MGI:MGI:1861691|Ensembl:ENSMUSG00000067242|Vega:OTTMUSG00000016342 +56843 Trpm5 MGI:MGI:1861718|Ensembl:ENSMUSG00000009246|Vega:OTTMUSG00000022683 +56844 Tssc4 MGI:MGI:1861712|Ensembl:ENSMUSG00000045752|Vega:OTTMUSG00000022684 +56846 Necab3 MGI:MGI:1861721|Ensembl:ENSMUSG00000027489|Vega:OTTMUSG00000015792 +56847 Aldh1a3 MGI:MGI:1861722|Ensembl:ENSMUSG00000015134|Vega:OTTMUSG00000036917 +56856 Insm2 MGI:MGI:1930787|Ensembl:ENSMUSG00000045440 +56857 Slc37a2 MGI:MGI:1929693|Ensembl:ENSMUSG00000032122|Vega:OTTMUSG00000033306 +56858 Olfr749 MGI:MGI:3030583|Ensembl:ENSMUSG00000059069|Vega:OTTMUSG00000058491 +56860 Olfr690 MGI:MGI:3030524|Ensembl:ENSMUSG00000050266|Vega:OTTMUSG00000060656 +56861 Olfr480 MGI:MGI:3030314|Ensembl:ENSMUSG00000063120|Vega:OTTMUSG00000059962 +56863 Cldn9 MGI:MGI:1913100|Ensembl:ENSMUSG00000066720|Vega:OTTMUSG00000033035 +56868 Psg23 MGI:MGI:1891355|Ensembl:ENSMUSG00000074359|Vega:OTTMUSG00000043491 +56869 Zfp109 MGI:MGI:1929099|Ensembl:ENSMUSG00000074283|Vega:OTTMUSG00000058069 +56872 Pate4 MGI:MGI:1930790|Ensembl:ENSMUSG00000032099|Vega:OTTMUSG00000030729 +56873 Lmbr1 MGI:MGI:1861746|Ensembl:ENSMUSG00000010721|Vega:OTTMUSG00000054257 +56874 Rnf32 MGI:MGI:1861747|Ensembl:ENSMUSG00000029130|Vega:OTTMUSG00000030390 +56876 Nsmf MGI:MGI:1861755|Ensembl:ENSMUSG00000006476|Vega:OTTMUSG00000011615 +56878 Rbms1 MGI:MGI:1861774|Ensembl:ENSMUSG00000026970|Vega:OTTMUSG00000016821 +56880 D5Kng3 MGI:MGI:1861751 +57014 Htr3b MGI:MGI:1861899|Ensembl:ENSMUSG00000008590|Vega:OTTMUSG00000063012 +57028 Pdxp MGI:MGI:1919282|Ensembl:ENSMUSG00000022436 +57080 Gtf2ird1 MGI:MGI:1861942|Ensembl:ENSMUSG00000023079|Vega:OTTMUSG00000055742 +57081 D5Kng2 MGI:MGI:1861750 +57138 Slc12a5 MGI:MGI:1862037|Ensembl:ENSMUSG00000017740|Vega:OTTMUSG00000019699 +57170 Dolpp1 MGI:MGI:1914093|Ensembl:ENSMUSG00000026856|Vega:OTTMUSG00000016798 +57230 Sap30bp MGI:MGI:1927479|Ensembl:ENSMUSG00000020755|Vega:OTTMUSG00000003654 +57246 Tbx20 MGI:MGI:1888496|Ensembl:ENSMUSG00000031965|Vega:OTTMUSG00000062545 +57247 Zfp276 MGI:MGI:1888495|Ensembl:ENSMUSG00000001065|Vega:OTTMUSG00000022150 +57248 Ly6i MGI:MGI:1888480|Ensembl:ENSMUSG00000022586|Vega:OTTMUSG00000045160 +57249 Gabrq MGI:MGI:1888498|Ensembl:ENSMUSG00000031344|Vega:OTTMUSG00000017852 +57250 Olfr653 MGI:MGI:3030487|Ensembl:ENSMUSG00000073926|Vega:OTTMUSG00000019187 +57251 Olfr870 MGI:MGI:3030704|Ensembl:ENSMUSG00000066899|Vega:OTTMUSG00000061730 +57252 Tas2r105 MGI:MGI:2681195|Ensembl:ENSMUSG00000051153|Vega:OTTMUSG00000056787 +57253 Tas2r108 MGI:MGI:2681210|Ensembl:ENSMUSG00000037140|Vega:OTTMUSG00000056377 +57254 Tas2r119 MGI:MGI:2681253|Ensembl:ENSMUSG00000045267|Vega:OTTMUSG00000057546 +57255 Cldn13 MGI:MGI:1913102|Ensembl:ENSMUSG00000008843|Vega:OTTMUSG00000025978 +57256 Prss21 MGI:MGI:1916698|Ensembl:ENSMUSG00000024116|Vega:OTTMUSG00000023199 +57257 Vav3 MGI:MGI:1888518|Ensembl:ENSMUSG00000033721|Vega:OTTMUSG00000007363 +57258 Xpo4 MGI:MGI:1888526|Ensembl:ENSMUSG00000021952|Vega:OTTMUSG00000037617 +57259 Tob2 MGI:MGI:1888525|Ensembl:ENSMUSG00000048546 +57260 Ltb4r2 MGI:MGI:1888501|Ensembl:ENSMUSG00000040432 +57261 Brd4 MGI:MGI:1888520|Ensembl:ENSMUSG00000024002|Vega:OTTMUSG00000030241 +57262 Retnla MGI:MGI:1888504|Ensembl:ENSMUSG00000061100 +57263 Retnlb MGI:MGI:1888505|Ensembl:ENSMUSG00000022650 +57264 Retn MGI:MGI:1888506|Ensembl:ENSMUSG00000012705|Vega:OTTMUSG00000030662 +57265 Fzd2 MGI:MGI:1888513|Ensembl:ENSMUSG00000050288|Vega:OTTMUSG00000002949 +57266 Cxcl14 MGI:MGI:1888514|Ensembl:ENSMUSG00000021508 +57267 Apba3 MGI:MGI:1888527|Ensembl:ENSMUSG00000004931 +57269 Olfr1507 MGI:MGI:3031341|Ensembl:ENSMUSG00000059887 +57270 Olfr1508 MGI:MGI:3031342|Ensembl:ENSMUSG00000057564|Vega:OTTMUSG00000053573 +57271 Olfr1509 MGI:MGI:3031343|Ensembl:ENSMUSG00000035626|Vega:OTTMUSG00000053563 +57272 Olfr140 MGI:MGI:2177523|Ensembl:ENSMUSG00000075068|Vega:OTTMUSG00000014233 +57274 Slc16a8 MGI:MGI:1929519|Ensembl:ENSMUSG00000032988|Vega:OTTMUSG00000036033 +57275 Lenep MGI:MGI:1930020|Ensembl:ENSMUSG00000078173|Vega:OTTMUSG00000021951 +57276 Vsig2 MGI:MGI:1928009|Ensembl:ENSMUSG00000001943|Vega:OTTMUSG00000063094 +57277 Slurp1 MGI:MGI:1930923|Ensembl:ENSMUSG00000022596|Vega:OTTMUSG00000045148 +57278 Bcam MGI:MGI:1929940|Ensembl:ENSMUSG00000002980|Vega:OTTMUSG00000031720 +57279 Slc25a20 MGI:MGI:1928738|Ensembl:ENSMUSG00000032602|Vega:OTTMUSG00000050670 +57294 Rps27 MGI:MGI:1888676|Ensembl:ENSMUSG00000090733|Vega:OTTMUSG00000052891 +57295 Icmt MGI:MGI:1888594|Ensembl:ENSMUSG00000039662|Vega:OTTMUSG00000010407 +57296 Psmd8 MGI:MGI:1888669|Ensembl:ENSMUSG00000030591|Vega:OTTMUSG00000043396 +57312 Mrps31 MGI:MGI:1913153|Ensembl:ENSMUSG00000031533|Vega:OTTMUSG00000060887 +57314 Nelfcd MGI:MGI:1926424|Ensembl:ENSMUSG00000016253|Vega:OTTMUSG00000016459 +57315 Wdr46 MGI:MGI:1931871|Ensembl:ENSMUSG00000024312|Vega:OTTMUSG00000037083 +57316 C1d MGI:MGI:1927354|Ensembl:ENSMUSG00000000581|Vega:OTTMUSG00000005196 +57317 Srsf4 MGI:MGI:1890577|Ensembl:ENSMUSG00000028911|Vega:OTTMUSG00000009577 +57319 Smpdl3a MGI:MGI:1931437|Ensembl:ENSMUSG00000019872|Vega:OTTMUSG00000024048 +57320 Park7 MGI:MGI:2135637|Ensembl:ENSMUSG00000028964|Vega:OTTMUSG00000010158 +57321 Terf2ip MGI:MGI:1929871|Ensembl:ENSMUSG00000033430|Vega:OTTMUSG00000061808 +57329 Otor MGI:MGI:1888678|Ensembl:ENSMUSG00000027416|Vega:OTTMUSG00000015605 +57330 Gigyf1 MGI:MGI:1888677|Ensembl:ENSMUSG00000029714|Vega:OTTMUSG00000054539 +57339 Jph1 MGI:MGI:1891495|Ensembl:ENSMUSG00000042686|Vega:OTTMUSG00000048149 +57340 Jph3 MGI:MGI:1891497|Ensembl:ENSMUSG00000025318|Vega:OTTMUSG00000036743 +57342 Parva MGI:MGI:1931144|Ensembl:ENSMUSG00000030770|Vega:OTTMUSG00000024812 +57344 As3mt MGI:MGI:1929882|Ensembl:ENSMUSG00000003559 +57349 Ppbp MGI:MGI:1888712|Ensembl:ENSMUSG00000029372|Vega:OTTMUSG00000055504 +57350 D7Dmr1 MGI:MGI:1888692 +57354 Cramp1l MGI:MGI:1930190|Ensembl:ENSMUSG00000038002 +57355 BC051019 MGI:MGI:1928824|Ensembl:ENSMUSG00000031022|Vega:OTTMUSG00000023380 +57357 Srd5a3 MGI:MGI:1930252|Ensembl:ENSMUSG00000029233|Vega:OTTMUSG00000025182 +57370 B4galt3 MGI:MGI:1928767|Ensembl:ENSMUSG00000052423|Vega:OTTMUSG00000021683 +57373 Akip1 MGI:MGI:3041226|Ensembl:ENSMUSG00000031023|Vega:OTTMUSG00000023381 +57376 Smarce1 MGI:MGI:1927347|Ensembl:ENSMUSG00000037935|Vega:OTTMUSG00000006455 +57377 Mogs MGI:MGI:1929872|Ensembl:ENSMUSG00000030036|Vega:OTTMUSG00000024275 +57385 P2ry4 MGI:MGI:1926594|Ensembl:ENSMUSG00000044359|Vega:OTTMUSG00000018284 +57390 Psors1c2 MGI:MGI:1930025|Ensembl:ENSMUSG00000024409|Vega:OTTMUSG00000037237 +57394 Tmem27 MGI:MGI:1926234|Ensembl:ENSMUSG00000015401|Vega:OTTMUSG00000019509 +57421 Bhmt-ps1 MGI:MGI:1888909 +57423 Atp5j2 MGI:MGI:1927558|Ensembl:ENSMUSG00000038690|Vega:OTTMUSG00000023054 +57425 U90926 MGI:MGI:1930915|Ensembl:ENSMUSG00000029409|Vega:OTTMUSG00000055612 +57426 Scgb1b2 MGI:MGI:1930867|Ensembl:ENSMUSG00000062556|Vega:OTTMUSG00000045654 +57429 Sult5a1 MGI:MGI:1931463|Ensembl:ENSMUSG00000000739|Vega:OTTMUSG00000022141 +57430 Sult3a1 MGI:MGI:1931469|Ensembl:ENSMUSG00000069668 +57431 Dnajc4 MGI:MGI:1927346|Ensembl:ENSMUSG00000024963 +57432 Zc3h8 MGI:MGI:1930128|Ensembl:ENSMUSG00000027387|Vega:OTTMUSG00000015426 +57434 Xrcc2 MGI:MGI:1927345|Ensembl:ENSMUSG00000028933|Vega:OTTMUSG00000024269 +57435 Plin4 MGI:MGI:1929709|Ensembl:ENSMUSG00000002831|Vega:OTTMUSG00000046184 +57436 Gabarapl1 MGI:MGI:1914980|Ensembl:ENSMUSG00000030161|Vega:OTTMUSG00000056471 +57437 Golga7 MGI:MGI:1931029|Ensembl:ENSMUSG00000015341|Vega:OTTMUSG00000029863 +57438 March7 MGI:MGI:1931053|Ensembl:ENSMUSG00000026977|Vega:OTTMUSG00000012814 +57439 Tmem183a MGI:MGI:1914729|Ensembl:ENSMUSG00000042305|Vega:OTTMUSG00000049679 +57440 Ehd3 MGI:MGI:1928900|Ensembl:ENSMUSG00000024065|Vega:OTTMUSG00000028496 +57441 Gmnn MGI:MGI:1927344|Ensembl:ENSMUSG00000006715|Vega:OTTMUSG00000000611 +57442 Kcne3 MGI:MGI:1891124|Ensembl:ENSMUSG00000035165|Vega:OTTMUSG00000059142 +57443 Fbxo3 MGI:MGI:1929084|Ensembl:ENSMUSG00000027180|Vega:OTTMUSG00000014914 +57444 Isg20 MGI:MGI:1928895|Ensembl:ENSMUSG00000039236|Vega:OTTMUSG00000027310 +57737 Rhox4b MGI:MGI:1930129|Ensembl:ENSMUSG00000071771|Vega:OTTMUSG00000017139 +57738 Slc15a2 MGI:MGI:1890457|Ensembl:ENSMUSG00000022899|Vega:OTTMUSG00000035783 +57740 Stk32c MGI:MGI:2385336|Ensembl:ENSMUSG00000015981|Vega:OTTMUSG00000023219 +57741 Noc2l MGI:MGI:1931051|Ensembl:ENSMUSG00000095567 +57742 Abhd1 MGI:MGI:1931013|Ensembl:ENSMUSG00000006638 +57743 Sec61a2 MGI:MGI:1931071|Ensembl:ENSMUSG00000025816|Vega:OTTMUSG00000010876 +57745 Zfp112 MGI:MGI:1929115|Ensembl:ENSMUSG00000052675|Vega:OTTMUSG00000027156 +57746 Piwil2 MGI:MGI:1930036|Ensembl:ENSMUSG00000033644 +57748 Jmy MGI:MGI:1913096|Ensembl:ENSMUSG00000021690 +57749 Piwil1 MGI:MGI:1928897|Ensembl:ENSMUSG00000029423|Vega:OTTMUSG00000055208 +57750 Wdr12 MGI:MGI:1927241|Ensembl:ENSMUSG00000026019|Vega:OTTMUSG00000021598 +57751 Rnf25 MGI:MGI:1890215|Ensembl:ENSMUSG00000026171|Vega:OTTMUSG00000021746 +57752 Tacc2 MGI:MGI:1928899|Ensembl:ENSMUSG00000030852|Vega:OTTMUSG00000059551 +57753 Noc3l MGI:MGI:1932610|Ensembl:ENSMUSG00000024999 +57754 Cend1 MGI:MGI:1929898|Ensembl:ENSMUSG00000060240|Vega:OTTMUSG00000034077 +57755 Dnajb7 MGI:MGI:1914012|Ensembl:ENSMUSG00000047108|Vega:OTTMUSG00000035641 +57756 Fhl5 MGI:MGI:1913192|Ensembl:ENSMUSG00000028259|Vega:OTTMUSG00000004835 +57757 Pglyrp2 MGI:MGI:1928099|Ensembl:ENSMUSG00000079563 +57764 Ntn4 MGI:MGI:1888978|Ensembl:ENSMUSG00000020019|Vega:OTTMUSG00000027786 +57765 Tbx21 MGI:MGI:1888984|Ensembl:ENSMUSG00000001444|Vega:OTTMUSG00000002233 +57773 Wdr4 MGI:MGI:1889002|Ensembl:ENSMUSG00000024037|Vega:OTTMUSG00000035223 +57775 Usp29 MGI:MGI:1888998|Ensembl:ENSMUSG00000051527|Vega:OTTMUSG00000054322 +57776 Ttyh1 MGI:MGI:1889007|Ensembl:ENSMUSG00000030428|Vega:OTTMUSG00000021913 +57778 Fmnl1 MGI:MGI:1888994|Ensembl:ENSMUSG00000055805|Vega:OTTMUSG00000003031 +57780 Fxyd7 MGI:MGI:1889006|Ensembl:ENSMUSG00000036578|Vega:OTTMUSG00000058037 +57781 Cd200r1 MGI:MGI:1889024|Ensembl:ENSMUSG00000022667|Vega:OTTMUSG00000014978 +57782 Rbak MGI:MGI:1927369|Ensembl:ENSMUSG00000061898|Vega:OTTMUSG00000036790 +57783 Tnip1 MGI:MGI:1926194|Ensembl:ENSMUSG00000020400|Vega:OTTMUSG00000006334 +57784 Bin3 MGI:MGI:1929883|Ensembl:ENSMUSG00000022089 +57785 Rangrf MGI:MGI:1889073|Ensembl:ENSMUSG00000032892|Vega:OTTMUSG00000005954 +57808 Rpl35a MGI:MGI:1928894|Ensembl:ENSMUSG00000060636|Vega:OTTMUSG00000024790 +57810 Cdon MGI:MGI:1926387|Ensembl:ENSMUSG00000038119|Vega:OTTMUSG00000030743 +57811 Rgr MGI:MGI:1929473|Ensembl:ENSMUSG00000021804 +57813 Tk2 MGI:MGI:1913266|Ensembl:ENSMUSG00000035824|Vega:OTTMUSG00000061874 +57814 Kcne4 MGI:MGI:1891125|Ensembl:ENSMUSG00000047330|Vega:OTTMUSG00000047860 +57815 Spata5 MGI:MGI:1927170|Ensembl:ENSMUSG00000027722|Vega:OTTMUSG00000007434 +57816 Tesc MGI:MGI:1930803|Ensembl:ENSMUSG00000029359|Vega:OTTMUSG00000021294 +57837 Eral1 MGI:MGI:1889295|Ensembl:ENSMUSG00000020832|Vega:OTTMUSG00000000074 +57866 AA545190 MGI:MGI:1889333 +57869 Adck2 MGI:MGI:1889336|Ensembl:ENSMUSG00000046947|Vega:OTTMUSG00000056325 +57874 Hacd3 MGI:MGI:1889341|Ensembl:ENSMUSG00000033629|Vega:OTTMUSG00000062616 +57875 Angptl4 MGI:MGI:1888999|Ensembl:ENSMUSG00000002289|Vega:OTTMUSG00000037206 +57878 AA414988 MGI:MGI:1889355 +57879 AA517463 MGI:MGI:1889356 +57880 AA517562 MGI:MGI:1889357 +57882 AA517653 MGI:MGI:1889363 +57889 AA589488 MGI:MGI:1889370 +57890 Il17re MGI:MGI:1889371|Ensembl:ENSMUSG00000043088|Vega:OTTMUSG00000056372 +57891 AA589522 MGI:MGI:1889372 +57895 Ccdc126 MGI:MGI:1889376|Ensembl:ENSMUSG00000050786|Vega:OTTMUSG00000022930 +57896 Krcc1 MGI:MGI:1889377|Ensembl:ENSMUSG00000053012|Vega:OTTMUSG00000057910 +57900 D6Mgi34 MGI:MGI:1889381 +57905 Isy1 MGI:MGI:1923310|Ensembl:ENSMUSG00000030056|Vega:OTTMUSG00000057272 +57908 Zfp318 MGI:MGI:1889348|Ensembl:ENSMUSG00000015597|Vega:OTTMUSG00000023200 +57911 Gsdma MGI:MGI:1889509|Ensembl:ENSMUSG00000017204|Vega:OTTMUSG00000006393 +57912 Cdc42se1 MGI:MGI:1889510|Ensembl:ENSMUSG00000046722|Vega:OTTMUSG00000022348 +57913 Pidd1 MGI:MGI:1889507|Ensembl:ENSMUSG00000025507|Vega:OTTMUSG00000024561 +57914 Crlf2 MGI:MGI:1889506|Ensembl:ENSMUSG00000033467|Vega:OTTMUSG00000054032 +57915 Tbc1d1 MGI:MGI:1889508|Ensembl:ENSMUSG00000029174|Vega:OTTMUSG00000026476 +57916 Tnfrsf13b MGI:MGI:1889411|Ensembl:ENSMUSG00000010142|Vega:OTTMUSG00000005824 +58170 Asic5 MGI:MGI:1929259|Ensembl:ENSMUSG00000028008|Vega:OTTMUSG00000024258 +58172 Sertad2 MGI:MGI:1931026|Ensembl:ENSMUSG00000049800|Vega:OTTMUSG00000005229 +58175 Rgs20 MGI:MGI:1929866|Ensembl:ENSMUSG00000002459|Vega:OTTMUSG00000029338 +58176 Rhbg MGI:MGI:1927379|Ensembl:ENSMUSG00000103766|Ensembl:ENSMUSG00000104445|Vega:OTTMUSG00000035936|Vega:OTTMUSG00000052140 +58178 Sorcs1 MGI:MGI:1929666|Ensembl:ENSMUSG00000043531|Vega:OTTMUSG00000060510 +58179 Klrc3 MGI:MGI:1929720|Ensembl:ENSMUSG00000033027|Vega:OTTMUSG00000032507 +58180 Hic2 MGI:MGI:1929869|Ensembl:ENSMUSG00000050240|Vega:OTTMUSG00000038081 +58181 Il20 MGI:MGI:1890473|Ensembl:ENSMUSG00000026416|Vega:OTTMUSG00000049114 +58182 Prokr1 MGI:MGI:1929676|Ensembl:ENSMUSG00000049409|Vega:OTTMUSG00000057205 +58184 Cnot9 MGI:MGI:1928902|Ensembl:ENSMUSG00000026174|Vega:OTTMUSG00000021742 +58185 Rsad2 MGI:MGI:1929628|Ensembl:ENSMUSG00000020641|Vega:OTTMUSG00000027569 +58186 Rad18 MGI:MGI:1890476|Ensembl:ENSMUSG00000030254|Vega:OTTMUSG00000017314 +58187 Cldn10 MGI:MGI:1913101|Ensembl:ENSMUSG00000022132|Vega:OTTMUSG00000023307 +58188 Vstm2b MGI:MGI:1914525|Ensembl:ENSMUSG00000039257|Vega:OTTMUSG00000049457 +58193 Extl2 MGI:MGI:1889574|Ensembl:ENSMUSG00000027963|Vega:OTTMUSG00000022635 +58194 Sh3kbp1 MGI:MGI:1889583|Ensembl:ENSMUSG00000040990|Vega:OTTMUSG00000019443 +58198 Sall1 MGI:MGI:1889585|Ensembl:ENSMUSG00000031665|Vega:OTTMUSG00000061533 +58200 Ppp1r1a MGI:MGI:1889595|Ensembl:ENSMUSG00000022490 +58202 Nelfb MGI:MGI:1931035|Ensembl:ENSMUSG00000013465|Vega:OTTMUSG00000011781 +58203 Zbp1 MGI:MGI:1927449|Ensembl:ENSMUSG00000027514|Vega:OTTMUSG00000016683 +58205 Pdcd1lg2 MGI:MGI:1930125|Ensembl:ENSMUSG00000016498|Vega:OTTMUSG00000014902 +58206 Zbtb32 MGI:MGI:1891838|Ensembl:ENSMUSG00000006310|Vega:OTTMUSG00000023052 +58207 Slc43a3 MGI:MGI:1931054|Ensembl:ENSMUSG00000027074|Vega:OTTMUSG00000013409 +58208 Bcl11b MGI:MGI:1929913|Ensembl:ENSMUSG00000048251|Vega:OTTMUSG00000019485 +58210 Sectm1b MGI:MGI:1929083|Ensembl:ENSMUSG00000039364|Vega:OTTMUSG00000004164 +58212 Srrm3 MGI:MGI:1920309|Ensembl:ENSMUSG00000039860|Vega:OTTMUSG00000029498 +58213 AB041806 MGI:MGI:1931024 +58214 Cst10 MGI:MGI:1930004|Ensembl:ENSMUSG00000033156|Vega:OTTMUSG00000015751 +58217 Trem1 MGI:MGI:1930005|Ensembl:ENSMUSG00000042265|Vega:OTTMUSG00000016843 +58218 Trem3 MGI:MGI:1930003|Ensembl:ENSMUSG00000041754 +58220 Pard6b MGI:MGI:2135605|Ensembl:ENSMUSG00000044641|Vega:OTTMUSG00000016053 +58222 Rab37 MGI:MGI:1929945|Ensembl:ENSMUSG00000020732|Vega:OTTMUSG00000003609 +58223 Mmp19 MGI:MGI:1927899|Ensembl:ENSMUSG00000025355 +58226 Cacna1h MGI:MGI:1928842|Ensembl:ENSMUSG00000024112|Vega:OTTMUSG00000034314 +58227 Fam184b MGI:MGI:2442958|Ensembl:ENSMUSG00000015879|Vega:OTTMUSG00000053977 +58229 Efcc1 MGI:MGI:3611451|Ensembl:ENSMUSG00000068263|Vega:OTTMUSG00000034550 +58230 Rnf8 MGI:MGI:1929069|Ensembl:ENSMUSG00000090083|Vega:OTTMUSG00000034432 +58231 Stk4 MGI:MGI:1929004|Ensembl:ENSMUSG00000018209|Vega:OTTMUSG00000001179 +58233 Dnaja4 MGI:MGI:1927638|Ensembl:ENSMUSG00000032285|Vega:OTTMUSG00000027391 +58234 Shank3 MGI:MGI:1930016|Ensembl:ENSMUSG00000022623|Vega:OTTMUSG00000024288 +58235 Nectin1 MGI:MGI:1926483|Ensembl:ENSMUSG00000032012|Vega:OTTMUSG00000063167 +58237 Nkain4 MGI:MGI:1915372|Ensembl:ENSMUSG00000027574|Vega:OTTMUSG00000016392 +58238 Fam181b MGI:MGI:1930951|Ensembl:ENSMUSG00000051515|Vega:OTTMUSG00000059838 +58239 Dexi MGI:MGI:1926236|Ensembl:ENSMUSG00000038055|Vega:OTTMUSG00000021256 +58240 Hs1bp3 MGI:MGI:1913224|Ensembl:ENSMUSG00000020605 +58242 Nudt11 MGI:MGI:1930957|Ensembl:ENSMUSG00000073295|Vega:OTTMUSG00000016673 +58243 Nap1l5 MGI:MGI:1923555|Ensembl:ENSMUSG00000055430|Vega:OTTMUSG00000057705 +58244 Stx6 MGI:MGI:1926235|Ensembl:ENSMUSG00000026470|Vega:OTTMUSG00000049966 +58245 Gpr180 MGI:MGI:1930949|Ensembl:ENSMUSG00000022131 +58246 Slc35b4 MGI:MGI:1931249|Ensembl:ENSMUSG00000018999|Vega:OTTMUSG00000014770 +58248 1700123O20Rik MGI:MGI:1920893|Ensembl:ENSMUSG00000040822 +58249 Fibp MGI:MGI:1926233|Ensembl:ENSMUSG00000024911 +58250 Chst11 MGI:MGI:1927166|Ensembl:ENSMUSG00000034612|Vega:OTTMUSG00000027827 +58251 Cep295nl MGI:MGI:1929713|Ensembl:ENSMUSG00000076433|Vega:OTTMUSG00000003878 +58518 Cts6 MGI:MGI:1889619|Ensembl:ENSMUSG00000021441|Vega:OTTMUSG00000027751 +58520 Erg28 MGI:MGI:1915571|Ensembl:ENSMUSG00000021252|Vega:OTTMUSG00000032571 +58521 Eid1 MGI:MGI:1889651|Ensembl:ENSMUSG00000091337|Vega:OTTMUSG00000015346 +58522 Trim54 MGI:MGI:1889623|Ensembl:ENSMUSG00000062077|Vega:OTTMUSG00000022416 +58523 Elp2 MGI:MGI:1889642|Ensembl:ENSMUSG00000024271 +58539 D13Die38 MGI:MGI:1889670 +58540 D13Die39 MGI:MGI:1889671 +58541 D13Die40 MGI:MGI:1889672 +58542 D13Die41 MGI:MGI:1889673 +58543 D13Die42 MGI:MGI:1889674 +58544 D13Die43 MGI:MGI:1889675 +58545 D13Die44 MGI:MGI:1889676 +58546 D13Die45 MGI:MGI:1889677 +58547 D13Die46 MGI:MGI:1889678 +58799 Crbn MGI:MGI:1913277|Ensembl:ENSMUSG00000005362|Vega:OTTMUSG00000023530 +58800 Trpm7 MGI:MGI:1929996|Ensembl:ENSMUSG00000027365|Vega:OTTMUSG00000015961 +58801 Pmaip1 MGI:MGI:1930146|Ensembl:ENSMUSG00000024521 +58802 Kcnmb4 MGI:MGI:1913272|Ensembl:ENSMUSG00000054934|Vega:OTTMUSG00000036564 +58803 Pga5 MGI:MGI:1915935|Ensembl:ENSMUSG00000024738 +58804 Cdc42ep5 MGI:MGI:1929745|Ensembl:ENSMUSG00000063838|Vega:OTTMUSG00000027902 +58805 Mlxipl MGI:MGI:1927999|Ensembl:ENSMUSG00000005373|Vega:OTTMUSG00000025974 +58807 Slco1c1 MGI:MGI:1889679|Ensembl:ENSMUSG00000030235|Vega:OTTMUSG00000021195 +58809 Rnase4 MGI:MGI:1926217|Ensembl:ENSMUSG00000021876 +58810 Akr1a1 MGI:MGI:1929955|Ensembl:ENSMUSG00000028692|Vega:OTTMUSG00000009532 +58859 Efemp2 MGI:MGI:1891209|Ensembl:ENSMUSG00000024909|Vega:OTTMUSG00000036759 +58860 Adamdec1 MGI:MGI:1917650|Ensembl:ENSMUSG00000022057 +58861 Cysltr1 MGI:MGI:1926218|Ensembl:ENSMUSG00000052821|Vega:OTTMUSG00000018272 +58864 Tssk3 MGI:MGI:1929914|Ensembl:ENSMUSG00000000411|Vega:OTTMUSG00000009663 +58865 Tdh MGI:MGI:1926231|Ensembl:ENSMUSG00000021953|Vega:OTTMUSG00000035533 +58866 Treh MGI:MGI:1926230|Ensembl:ENSMUSG00000032098|Vega:OTTMUSG00000033497 +58867 Syngr4 MGI:MGI:1928903|Ensembl:ENSMUSG00000040231|Vega:OTTMUSG00000030552 +58869 Pex5l MGI:MGI:1916672|Ensembl:ENSMUSG00000027674|Vega:OTTMUSG00000023437 +58875 Hibadh MGI:MGI:1889802|Ensembl:ENSMUSG00000029776|Vega:OTTMUSG00000023439 +58882 AI324858 MGI:MGI:1889812 +58887 Repin1 MGI:MGI:1889817|Ensembl:ENSMUSG00000052751|Vega:OTTMUSG00000029701 +58894 Zfp862-ps MGI:MGI:1889827|Ensembl:ENSMUSG00000107476 +58899 A130009E19Rik MGI:MGI:1889832 +58901 AI449595 MGI:MGI:1889834 +58909 Fam13a MGI:MGI:1889842|Ensembl:ENSMUSG00000037709|Vega:OTTMUSG00000036934 +58911 Sumf1 MGI:MGI:1889844|Ensembl:ENSMUSG00000030101|Vega:OTTMUSG00000035993 +58916 Myot MGI:MGI:1889800|Ensembl:ENSMUSG00000024471|Vega:OTTMUSG00000014922 +58988 Rps6kb2 MGI:MGI:1927343|Ensembl:ENSMUSG00000024830|Vega:OTTMUSG00000028311 +58991 Ghrl MGI:MGI:1930008|Ensembl:ENSMUSG00000064177|Vega:OTTMUSG00000056499 +58992 F12 MGI:MGI:1891012|Ensembl:ENSMUSG00000021492|Vega:OTTMUSG00000035495 +58994 Smpd3 MGI:MGI:1927578|Ensembl:ENSMUSG00000031906|Vega:OTTMUSG00000061946 +58996 Arhgap23 MGI:MGI:3697726|Ensembl:ENSMUSG00000049807|Vega:OTTMUSG00000002673 +58998 Nectin3 MGI:MGI:1930171|Ensembl:ENSMUSG00000022656|Vega:OTTMUSG00000014968 +59001 Pole3 MGI:MGI:1933378|Ensembl:ENSMUSG00000028394|Vega:OTTMUSG00000009021 +59002 Wrap73 MGI:MGI:1891749|Ensembl:ENSMUSG00000029029|Vega:OTTMUSG00000010506 +59003 Maea MGI:MGI:1891748|Ensembl:ENSMUSG00000079562|Vega:OTTMUSG00000055361 +59004 Pias4 MGI:MGI:2136940|Ensembl:ENSMUSG00000004934|Vega:OTTMUSG00000030312 +59005 Trappc2l MGI:MGI:1916295|Ensembl:ENSMUSG00000015013|Vega:OTTMUSG00000061860 +59006 Myoz2 MGI:MGI:1913063|Ensembl:ENSMUSG00000028116|Vega:OTTMUSG00000029055 +59007 Ngly1 MGI:MGI:1913276|Ensembl:ENSMUSG00000021785|Vega:OTTMUSG00000023283 +59008 Anapc5 MGI:MGI:1929722|Ensembl:ENSMUSG00000029472|Vega:OTTMUSG00000054578 +59009 Sh3rf1 MGI:MGI:1913066|Ensembl:ENSMUSG00000031642|Vega:OTTMUSG00000060965 +59010 Sqor MGI:MGI:1929899|Ensembl:ENSMUSG00000005803|Vega:OTTMUSG00000015682 +59011 Myoz1 MGI:MGI:1929471|Ensembl:ENSMUSG00000068697 +59012 Moxd1 MGI:MGI:1921582|Ensembl:ENSMUSG00000020000|Vega:OTTMUSG00000019715 +59013 Hnrnph1 MGI:MGI:1891925|Ensembl:ENSMUSG00000007850|Vega:OTTMUSG00000005583 +59014 Rrs1 MGI:MGI:1929721|Ensembl:ENSMUSG00000061024|Vega:OTTMUSG00000045230 +59015 Nup160 MGI:MGI:1926227|Ensembl:ENSMUSG00000051329|Vega:OTTMUSG00000014277 +59016 Thap11 MGI:MGI:1930964|Ensembl:ENSMUSG00000036442|Vega:OTTMUSG00000062060 +59020 Pdzk1 MGI:MGI:1928901|Ensembl:ENSMUSG00000038298|Vega:OTTMUSG00000024711 +59021 Rab2a MGI:MGI:1928750|Ensembl:ENSMUSG00000047187|Vega:OTTMUSG00000004419 +59022 Edf1 MGI:MGI:1891227|Ensembl:ENSMUSG00000015092|Vega:OTTMUSG00000012162 +59024 Med12 MGI:MGI:1926212|Ensembl:ENSMUSG00000079487|Vega:OTTMUSG00000018212 +59025 Usp14 MGI:MGI:1928898|Ensembl:ENSMUSG00000047879|Vega:OTTMUSG00000020274 +59026 Huwe1 MGI:MGI:1926884|Ensembl:ENSMUSG00000025261|Vega:OTTMUSG00000019367 +59027 Nampt MGI:MGI:1929865|Ensembl:ENSMUSG00000020572 +59028 Rcl1 MGI:MGI:1913275|Ensembl:ENSMUSG00000024785 +59029 Psmd14 MGI:MGI:1913284|Ensembl:ENSMUSG00000026914|Vega:OTTMUSG00000013076 +59030 Mkks MGI:MGI:1891836|Ensembl:ENSMUSG00000027274|Vega:OTTMUSG00000015555 +59031 Chst12 MGI:MGI:1929064|Ensembl:ENSMUSG00000036599|Vega:OTTMUSG00000025896 +59032 Ppp2r3c MGI:MGI:1930009|Ensembl:ENSMUSG00000021022 +59033 Slc4a8 MGI:MGI:1928745|Ensembl:ENSMUSG00000023032|Vega:OTTMUSG00000035009 +59035 Carm1 MGI:MGI:1913208|Ensembl:ENSMUSG00000032185|Vega:OTTMUSG00000020639 +59036 Dact1 MGI:MGI:1891740|Ensembl:ENSMUSG00000044548|Vega:OTTMUSG00000033610 +59038 Pxmp4 MGI:MGI:1891701|Ensembl:ENSMUSG00000000876|Vega:OTTMUSG00000015921 +59040 Rhot1 MGI:MGI:1926078|Ensembl:ENSMUSG00000017686|Vega:OTTMUSG00000000219 +59041 Stk25 MGI:MGI:1891699|Ensembl:ENSMUSG00000026277|Vega:OTTMUSG00000026452 +59042 Cope MGI:MGI:1891702|Ensembl:ENSMUSG00000055681|Vega:OTTMUSG00000027332 +59043 Wsb2 MGI:MGI:2144041|Ensembl:ENSMUSG00000029364|Vega:OTTMUSG00000025770 +59044 Rnf130 MGI:MGI:1891717|Ensembl:ENSMUSG00000020376|Vega:OTTMUSG00000005572 +59045 Stard3 MGI:MGI:1929618|Ensembl:ENSMUSG00000018167|Vega:OTTMUSG00000002712 +59046 Arpp19 MGI:MGI:1891691|Ensembl:ENSMUSG00000007656|Vega:OTTMUSG00000036813 +59047 Pnkp MGI:MGI:1891698|Ensembl:ENSMUSG00000002963|Vega:OTTMUSG00000022325 +59048 C1galt1c1 MGI:MGI:1913493|Ensembl:ENSMUSG00000048970|Vega:OTTMUSG00000017234 +59049 Slc22a17 MGI:MGI:1926225|Ensembl:ENSMUSG00000022199 +59050 Nsa2 MGI:MGI:1913883|Ensembl:ENSMUSG00000060739 +59052 Mettl9 MGI:MGI:1914862|Ensembl:ENSMUSG00000030876|Vega:OTTMUSG00000059378 +59053 Hgh1 MGI:MGI:1930628|Ensembl:ENSMUSG00000022554 +59054 Mrps30 MGI:MGI:1926237|Ensembl:ENSMUSG00000021731|Vega:OTTMUSG00000032637 +59056 Evc MGI:MGI:1890596|Ensembl:ENSMUSG00000029122|Vega:OTTMUSG00000024883 +59057 Zfp24 MGI:MGI:1929704|Ensembl:ENSMUSG00000051469|Vega:OTTMUSG00000032638 +59058 Bhlhe22 MGI:MGI:1930001|Ensembl:ENSMUSG00000025128|Vega:OTTMUSG00000018225 +59069 Tpm3 MGI:MGI:1890149|Ensembl:ENSMUSG00000027940|Vega:OTTMUSG00000029647 +59079 Erbin MGI:MGI:1890169|Ensembl:ENSMUSG00000021709|Vega:OTTMUSG00000049022 +59083 Fetub MGI:MGI:1890221|Ensembl:ENSMUSG00000022871 +59090 Midn MGI:MGI:1890222|Ensembl:ENSMUSG00000035621|Vega:OTTMUSG00000000001 +59091 Jph2 MGI:MGI:1891496|Ensembl:ENSMUSG00000017817|Vega:OTTMUSG00000001147 +59092 Pcbp4 MGI:MGI:1890471|Ensembl:ENSMUSG00000023495|Vega:OTTMUSG00000049661 +59093 Pcbp3 MGI:MGI:1890470|Ensembl:ENSMUSG00000001120|Vega:OTTMUSG00000035211 +59095 Fxyd6 MGI:MGI:1890226|Ensembl:ENSMUSG00000066705|Vega:OTTMUSG00000063480 +59125 Nek7 MGI:MGI:1890645|Ensembl:ENSMUSG00000026393|Vega:OTTMUSG00000049434 +59126 Nek6 MGI:MGI:1891638|Ensembl:ENSMUSG00000026749|Vega:OTTMUSG00000012863 +59287 Ncstn MGI:MGI:1891700|Ensembl:ENSMUSG00000003458|Vega:OTTMUSG00000021508 +59288 Dctn5 MGI:MGI:1891689|Ensembl:ENSMUSG00000030868|Vega:OTTMUSG00000022642 +59289 Ackr2 MGI:MGI:1891697|Ensembl:ENSMUSG00000044534|Vega:OTTMUSG00000062682 +59290 Gpa33 MGI:MGI:1891703|Ensembl:ENSMUSG00000000544|Vega:OTTMUSG00000016903 +59308 Emcn MGI:MGI:1891716|Ensembl:ENSMUSG00000054690|Vega:OTTMUSG00000026580 +59310 Myl10 MGI:MGI:1891705|Ensembl:ENSMUSG00000005474|Vega:OTTMUSG00000054396 +60315 Myg1 MGI:MGI:1929864|Ensembl:ENSMUSG00000001285|Vega:OTTMUSG00000035795 +60321 Wbp11 MGI:MGI:1891823|Ensembl:ENSMUSG00000030216|Vega:OTTMUSG00000023417 +60322 Chst7 MGI:MGI:1891767|Ensembl:ENSMUSG00000037347|Vega:OTTMUSG00000017058 +60344 Fign MGI:MGI:1890647|Ensembl:ENSMUSG00000075324|Vega:OTTMUSG00000012785 +60345 Nrip2 MGI:MGI:1891884|Ensembl:ENSMUSG00000001520|Vega:OTTMUSG00000026982 +60361 Ms4a4b MGI:MGI:1913083|Ensembl:ENSMUSG00000056290|Vega:OTTMUSG00000028271 +60363 Cldn15 MGI:MGI:1913103|Ensembl:ENSMUSG00000001739|Vega:OTTMUSG00000023395 +60364 Donson MGI:MGI:1890621|Ensembl:ENSMUSG00000022960|Vega:OTTMUSG00000019888 +60365 Rbm8a MGI:MGI:1913129|Ensembl:ENSMUSG00000038374|Vega:OTTMUSG00000053140 +60367 Il1rapl2 MGI:MGI:1913106|Ensembl:ENSMUSG00000059203|Vega:OTTMUSG00000016978 +60406 Sap30 MGI:MGI:1929129|Ensembl:ENSMUSG00000031609|Vega:OTTMUSG00000029898 +60409 Trappc4 MGI:MGI:1926211|Ensembl:ENSMUSG00000032112|Vega:OTTMUSG00000063274 +60411 Cenpk MGI:MGI:1926210|Ensembl:ENSMUSG00000021714 +60425 Doc2g MGI:MGI:1926250|Ensembl:ENSMUSG00000024871|Vega:OTTMUSG00000033436 +60440 Iigp1 MGI:MGI:1926259|Ensembl:ENSMUSG00000054072 +60441 Mrpl38 MGI:MGI:1926269|Ensembl:ENSMUSG00000020775|Vega:OTTMUSG00000003757 +60455 Tmem8 MGI:MGI:1926283|Ensembl:ENSMUSG00000024180|Vega:OTTMUSG00000021355 +60456 Smt3h1-ps MGI:MGI:1926282 +60504 Il21r MGI:MGI:1890475|Ensembl:ENSMUSG00000030745|Vega:OTTMUSG00000058203 +60505 Il21 MGI:MGI:1890474|Ensembl:ENSMUSG00000027718|Vega:OTTMUSG00000007350 +60507 Qtrt1 MGI:MGI:1931441|Ensembl:ENSMUSG00000002825|Vega:OTTMUSG00000063356 +60510 Syt9 MGI:MGI:1926373|Ensembl:ENSMUSG00000062542|Vega:OTTMUSG00000031453 +60525 Acss2 MGI:MGI:1890410|Ensembl:ENSMUSG00000027605|Vega:OTTMUSG00000016058 +60527 Fads3 MGI:MGI:1928740|Ensembl:ENSMUSG00000024664 +60530 Fignl1 MGI:MGI:1890648|Ensembl:ENSMUSG00000035455|Vega:OTTMUSG00000005160 +60531 Npvf MGI:MGI:1926488|Ensembl:ENSMUSG00000029831|Vega:OTTMUSG00000026965 +60532 Wtap MGI:MGI:1926395|Ensembl:ENSMUSG00000060475|Vega:OTTMUSG00000034274 +60533 Cd274 MGI:MGI:1926446|Ensembl:ENSMUSG00000016496|Vega:OTTMUSG00000014904 +60534 Fancg MGI:MGI:1926471|Ensembl:ENSMUSG00000028453|Vega:OTTMUSG00000006687 +60594 Capn12 MGI:MGI:1891369|Ensembl:ENSMUSG00000054083|Vega:OTTMUSG00000059152 +60595 Actn4 MGI:MGI:1890773|Ensembl:ENSMUSG00000054808|Vega:OTTMUSG00000016983 +60596 Gucy1a3 MGI:MGI:1926562|Ensembl:ENSMUSG00000033910|Vega:OTTMUSG00000051754 +60597 Mapk8ip2 MGI:MGI:1926555|Ensembl:ENSMUSG00000022619|Vega:OTTMUSG00000032609 +60599 Trp53inp1 MGI:MGI:1926609|Ensembl:ENSMUSG00000028211|Vega:OTTMUSG00000004505 +60611 Foxj2 MGI:MGI:1926805|Ensembl:ENSMUSG00000003154|Vega:OTTMUSG00000023356 +60613 Kcnq4 MGI:MGI:1926803|Ensembl:ENSMUSG00000028631|Vega:OTTMUSG00000008856 +60689 D4Mit144 MGI:MGI:92769 +60690 D4Mit1 MGI:MGI:92720 +60691 D1Mit3 MGI:MGI:91682 +60692 D1Mit7 MGI:MGI:91720 +60693 D2Mit8 MGI:MGI:92216 +60694 D4Mit7 MGI:MGI:92905 +60695 D6Mit9 MGI:MGI:93723 +60696 D8Mit5 MGI:MGI:94415 +60697 DXMit5 MGI:MGI:95124 +60698 D1Mit58 MGI:MGI:91708 +60699 D1Mit64 MGI:MGI:91714 +60700 D1Mit65 MGI:MGI:91715 +60701 D1Mit66 MGI:MGI:91716 +60702 D1Mit67 MGI:MGI:91717 +60703 D1Mit68 MGI:MGI:91718 +60704 D2Mit76 MGI:MGI:92212 +60705 D3Mit62 MGI:MGI:92533 +60706 D3Mit90 MGI:MGI:92563 +60707 D4Mit98 MGI:MGI:92935 +60708 D5Mit72 MGI:MGI:93373 +60709 D6Mit47 MGI:MGI:93678 +60710 D6Mit82 MGI:MGI:93715 +60711 D6Mit83 MGI:MGI:93716 +60712 D6Mit86 MGI:MGI:93719 +60713 D7Mit21 MGI:MGI:94034 +60714 D7Mit56 MGI:MGI:94079 +60715 D7Mit57 MGI:MGI:94080 +60716 D8Mit58 MGI:MGI:94424 +60717 D8Mit60 MGI:MGI:94427 +60718 D9Mit43 MGI:MGI:94735 +60719 D9Mit57 MGI:MGI:94748 +60720 D9Mit60 MGI:MGI:94752 +60721 D9Mit61 MGI:MGI:94753 +60722 D9Mit64 MGI:MGI:94756 +60723 D9Mit89 MGI:MGI:94781 +60724 D9Mit90 MGI:MGI:94783 +60725 DXMit26 MGI:MGI:95098 +60726 DXMit27 MGI:MGI:95099 +60727 DXMit54 MGI:MGI:95129 +60728 DXMit57 MGI:MGI:95132 +60729 DXMit85 MGI:MGI:95162 +60730 DXMit89 MGI:MGI:95165 +60731 D10Mit1 MGI:MGI:88714 +60732 D1Mit18 MGI:MGI:91556 +60733 D1Mit19 MGI:MGI:91567 +60734 D1Mit24 MGI:MGI:91622 +60735 D1Mit43 MGI:MGI:91692 +60736 D1Mit45 MGI:MGI:91694 +60737 D1Mit46 MGI:MGI:91695 +60738 D1Mit49 MGI:MGI:91698 +60739 D1Mit57 MGI:MGI:91707 +60740 D10Mit1001 MGI:MGI:91709 +60741 D1Mit70 MGI:MGI:91721 +60742 D1Mit74 MGI:MGI:91725 +60743 D1Mit76 MGI:MGI:91727 +60744 D1Mit77 MGI:MGI:91728 +60745 D1Mit84 MGI:MGI:91736 +60746 D1Mit86 MGI:MGI:91738 +60747 D1Mit89 MGI:MGI:91741 +60748 D1Mit91 MGI:MGI:91744 +60749 D1Mit94 MGI:MGI:91747 +60750 D1Mit96 MGI:MGI:91749 +60751 D2Mit22 MGI:MGI:92086 +60752 D2Mit32 MGI:MGI:92168 +60753 D2Mit34 MGI:MGI:92170 +60754 D2Mit41 MGI:MGI:92177 +60755 D2Mit49 MGI:MGI:92185 +60756 D2Mit51 MGI:MGI:92188 +60757 D2Mit52 MGI:MGI:92189 +60758 D2Mit53 MGI:MGI:92190 +60759 D2Mit55 MGI:MGI:92191 +60760 D2Mit56 MGI:MGI:92192 +60761 D2Mit57 MGI:MGI:92193 +60762 D2Mit58 MGI:MGI:92194 +60763 D2Mit61 MGI:MGI:92198 +60764 D2Mit62 MGI:MGI:92199 +60765 D2Mit65 MGI:MGI:92202 +60766 D2Mit69 MGI:MGI:92204 +60767 D2Mit71 MGI:MGI:92207 +60768 D2Mit81 MGI:MGI:92218 +60769 D2Mit83 MGI:MGI:92220 +60770 D2Mit84 MGI:MGI:92221 +60771 D2Mit89 MGI:MGI:92226 +60772 D2Mit92 MGI:MGI:92230 +60773 D2Mit94 MGI:MGI:92232 +60774 D2Mit97 MGI:MGI:92235 +60775 D3Mit10 MGI:MGI:92364 +60776 D3Mit12 MGI:MGI:92386 +60777 D3Mit14 MGI:MGI:92408 +60778 D3Mit17 MGI:MGI:92441 +60779 D3Mit19 MGI:MGI:92463 +60780 D3Mit31 MGI:MGI:92504 +60781 D3Mit32 MGI:MGI:92505 +60782 D3Mit38 MGI:MGI:92507 +60783 D3Mit39 MGI:MGI:92508 +60784 D3Mit41 MGI:MGI:92511 +60785 D3Mit42 MGI:MGI:92512 +60786 D3Mit43 MGI:MGI:92513 +60787 D3Mit44 MGI:MGI:92514 +60788 D3Mit45 MGI:MGI:92515 +60789 D3Mit55 MGI:MGI:92525 +60790 D3Mit56 MGI:MGI:92526 +60791 D3Mit59 MGI:MGI:92529 +60792 D3Mit64 MGI:MGI:92535 +60793 D3Mit65 MGI:MGI:92536 +60794 D3Mit66 MGI:MGI:92537 +60795 D3Mit70 MGI:MGI:92542 +60796 D3Mit74 MGI:MGI:92546 +60797 D3Mit75 MGI:MGI:92547 +60798 D3Mit76 MGI:MGI:92548 +60799 D3Mit89 MGI:MGI:92561 +60800 D3Mit95 MGI:MGI:92568 +60801 D3Mit97 MGI:MGI:92570 +60802 D3Mit99 MGI:MGI:92572 +60803 D4Mit14 MGI:MGI:92764 +60804 D4Mit16 MGI:MGI:92786 +60805 D4Mit29 MGI:MGI:92865 +60806 D4Mit31 MGI:MGI:92866 +60807 D4Mit33 MGI:MGI:92868 +60808 D4Mit38 MGI:MGI:92870 +60809 D4Mit39 MGI:MGI:92871 +60810 D4Mit40 MGI:MGI:92873 +60811 D4Mit42 MGI:MGI:92875 +60812 D4Mit43 MGI:MGI:92876 +60813 D4Mit46 MGI:MGI:92879 +60814 D4Mit47 MGI:MGI:92880 +60815 D4Mit51 MGI:MGI:92885 +60816 D4Mit54 MGI:MGI:92888 +60817 D4Mit58 MGI:MGI:92892 +60818 D4Mit59 MGI:MGI:92893 +60819 D17Mit1009 MGI:MGI:92895 +60820 D4Mit61 MGI:MGI:92896 +60821 D4Mit63 MGI:MGI:92898 +60822 D4Mit67 MGI:MGI:92902 +60823 D4Mit68 MGI:MGI:92903 +60824 D4Mit69 MGI:MGI:92904 +60825 D4Mit70 MGI:MGI:92906 +60826 D4Mit71 MGI:MGI:92907 +60827 D4Mit72 MGI:MGI:92908 +60828 D4Mit73 MGI:MGI:92909 +60829 D4Mit74 MGI:MGI:92910 +60830 D12Mit1002 MGI:MGI:92914 +60831 D4Mit79 MGI:MGI:92915 +60832 D4Mit80 MGI:MGI:92916 +60833 D4Mit81 MGI:MGI:92917 +60834 D4Mit82 MGI:MGI:92918 +60835 D4Mit90 MGI:MGI:92927 +60836 D4Mit91 MGI:MGI:92928 +60837 D4Mit93 MGI:MGI:92930 +60838 D5Mit10 MGI:MGI:93168 +60839 D5Mit11 MGI:MGI:93179 +60840 D5Mit20 MGI:MGI:93277 +60841 D5Mit41 MGI:MGI:93342 +60842 D5Mit52 MGI:MGI:93353 +60843 D5Mit57 MGI:MGI:93356 +60844 D5Mit58 MGI:MGI:93357 +60845 D5Mit62 MGI:MGI:93362 +60846 D5Mit63 MGI:MGI:93363 +60847 D5Mit65 MGI:MGI:93365 +60848 D5Mit66 MGI:MGI:93366 +60849 D5Mit67 MGI:MGI:93367 +60850 D5Mit68 MGI:MGI:93368 +60851 D5Mit73 MGI:MGI:93374 +60852 D5Mit75 MGI:MGI:93376 +60853 D5Mit89 MGI:MGI:93390 +60854 D5Mit90 MGI:MGI:93392 +60855 D5Mit93 MGI:MGI:93395 +60856 D6Mit14 MGI:MGI:93568 +60857 D6Mit15 MGI:MGI:93579 +60858 D6Mit22 MGI:MGI:93654 +60859 D6Mit29 MGI:MGI:93660 +60860 D6Mit33 MGI:MGI:93665 +60861 D6Mit38 MGI:MGI:93669 +60862 D6Mit41 MGI:MGI:93673 +60863 D6Mit53 MGI:MGI:93685 +60864 D6Mit54 MGI:MGI:93686 +60865 D6Mit55 MGI:MGI:93687 +60866 D6Mit57 MGI:MGI:93688 +60867 D6Mit58 MGI:MGI:93689 +60868 D6Mit59 MGI:MGI:93690 +60869 D6Mit63 MGI:MGI:93695 +60870 D6Mit68 MGI:MGI:93700 +60871 D6Mit71 MGI:MGI:93703 +60872 D1Mit1013 MGI:MGI:93705 +60873 D6Mit75 MGI:MGI:93707 +60874 D6Mit76 MGI:MGI:93708 +60875 D6Mit95 MGI:MGI:93729 +60876 D6Mit98 MGI:MGI:93732 +60877 D7Mit15 MGI:MGI:93969 +60878 D7Mit40 MGI:MGI:94067 +60879 D7Mit43 MGI:MGI:94069 +60880 D7Mit44 MGI:MGI:94070 +60881 D7Mit58 MGI:MGI:94081 +60882 D7Mit62 MGI:MGI:94083 +60883 D7Mit64 MGI:MGI:94085 +60884 D7Mit66 MGI:MGI:94087 +60885 D7Mit67 MGI:MGI:94088 +60886 D7Mit69 MGI:MGI:94090 +60887 D7Mit72 MGI:MGI:94094 +60888 D7Mit79 MGI:MGI:94101 +60889 D7Mit80 MGI:MGI:94103 +60890 D7Mit83 MGI:MGI:94106 +60891 D7Mit85 MGI:MGI:94108 +60892 D7Mit98 MGI:MGI:94122 +60893 D8Mit25 MGI:MGI:94391 +60894 D8Mit42 MGI:MGI:94407 +60895 D8Mit45 MGI:MGI:94410 +60896 D9Mit1000 MGI:MGI:94411 +60897 D8Mit47 MGI:MGI:94412 +60898 D8Mit50 MGI:MGI:94416 +60899 D8Mit53 MGI:MGI:94419 +60900 D8Mit55 MGI:MGI:94421 +60901 D8Mit56 MGI:MGI:94422 +60902 D8Mit64 MGI:MGI:94431 +60903 D8Mit65 MGI:MGI:94432 +60904 D8Mit66 MGI:MGI:94433 +60905 D8Mit67 MGI:MGI:94434 +60906 D8Mit68 MGI:MGI:94435 +60907 D8Mit79 MGI:MGI:94447 +60908 D8Mit80 MGI:MGI:94449 +60909 D8Mit85 MGI:MGI:94454 +60910 D8Mit86 MGI:MGI:94455 +60911 D8Mit88 MGI:MGI:94457 +60912 D8Mit91 MGI:MGI:94461 +60913 D8Mit92 MGI:MGI:94462 +60914 D8Mit93 MGI:MGI:94463 +60915 D8Mit96 MGI:MGI:94466 +60916 D8Mit98 MGI:MGI:94468 +60917 D9Mit18 MGI:MGI:94690 +60918 D9Mit19 MGI:MGI:94701 +60919 D9Mit24 MGI:MGI:94719 +60920 D9Mit35 MGI:MGI:94728 +60921 D9Mit36 MGI:MGI:94729 +60922 D9Mit46 MGI:MGI:94737 +60923 D9Mit48 MGI:MGI:94739 +60924 D9Mit52 MGI:MGI:94743 +60925 D9Mit53 MGI:MGI:94744 +60926 D9Mit56 MGI:MGI:94747 +60927 D9Mit66 MGI:MGI:94758 +60928 D9Mit67 MGI:MGI:94759 +60929 D9Mit73 MGI:MGI:94765 +60930 D9Mit78 MGI:MGI:94770 +60931 D9Mit80 MGI:MGI:94773 +60932 D9Mit82 MGI:MGI:94775 +60933 D9Mit88 MGI:MGI:94780 +60934 D9Mit97 MGI:MGI:94787 +60935 DXMit13 MGI:MGI:95085 +60936 DXMit28 MGI:MGI:95100 +60937 DXMit29 MGI:MGI:95101 +60938 DXMit31 MGI:MGI:95104 +60939 DXMit32 MGI:MGI:95105 +60940 DXMit33 MGI:MGI:95106 +60941 DXMit37 MGI:MGI:95110 +60942 DXMit38 MGI:MGI:95111 +60943 DXMit39 MGI:MGI:95112 +60944 DXMit41 MGI:MGI:95115 +60945 DXMit42 MGI:MGI:95116 +60946 DXMit46 MGI:MGI:95120 +60947 DXMit48 MGI:MGI:95122 +60948 DXMit49 MGI:MGI:95123 +60949 DXMit50 MGI:MGI:95125 +60950 DXMit62 MGI:MGI:95137 +60951 DXMit65 MGI:MGI:95140 +60952 DXMit73 MGI:MGI:95149 +60953 DXMit79 MGI:MGI:95155 +60954 DXMit81 MGI:MGI:95158 +60955 DXMit82 MGI:MGI:95159 +60956 DXMit83 MGI:MGI:95160 +60957 DXMit84 MGI:MGI:95161 +60958 DXMit87 MGI:MGI:95164 +60959 DXMit97 MGI:MGI:95174 +60960 D9Mit99 MGI:MGI:102224 +60961 D1Mit475 MGI:MGI:105621 +60962 D2Mit464 MGI:MGI:105659 +60963 D3Mit328 MGI:MGI:105705 +60964 D3Mit329 MGI:MGI:105706 +60965 D9Mit324 MGI:MGI:105756 +60966 DXMit203 MGI:MGI:105896 +60967 DXMit205 MGI:MGI:105898 +60968 D10Mit3 MGI:MGI:88813 +60969 D10Mit8 MGI:MGI:88865 +60970 D12Mit2 MGI:MGI:89435 +60971 D12Mit4 MGI:MGI:89449 +60972 D12Mit6 MGI:MGI:89467 +60973 D12Mit8 MGI:MGI:89489 +60974 D13Mit7 MGI:MGI:89797 +60975 D14Mit4 MGI:MGI:90044 +60976 D16Mit1 MGI:MGI:90454 +60977 D16Mit3 MGI:MGI:90498 +60978 D16Mit4 MGI:MGI:90509 +60979 D16Mit7 MGI:MGI:90542 +60980 D17Mit2 MGI:MGI:90807 +60981 D17Mit7 MGI:MGI:90861 +60982 D17Mit9 MGI:MGI:90882 +60983 D18Mit1 MGI:MGI:91016 +60984 D18Mit4 MGI:MGI:91092 +60985 D18Mit8 MGI:MGI:91136 +60986 D19Mit1 MGI:MGI:91215 +60987 D19Mit6 MGI:MGI:91272 +60988 D19Mit7 MGI:MGI:91283 +60989 D19Mit9 MGI:MGI:91292 +60990 D1Mit118 MGI:MGI:91488 +60991 D1Mit242 MGI:MGI:91625 +60992 D1Mit62 MGI:MGI:91712 +60993 D2Mit115 MGI:MGI:91972 +60994 D2Mit150 MGI:MGI:92011 +60995 D2Mit175 MGI:MGI:92038 +60996 D2Mit176 MGI:MGI:92039 +60997 D2Mit215 MGI:MGI:92081 +60998 D2Mit267 MGI:MGI:92137 +60999 D2Mit74 MGI:MGI:92210 +61000 D3Mit132 MGI:MGI:92400 +61001 D3Mit176 MGI:MGI:92448 +61002 D3Mit177 MGI:MGI:92449 +61003 D4Mit100 MGI:MGI:92721 +61004 D4Mit101 MGI:MGI:92722 +61005 D4Mit103 MGI:MGI:92724 +61006 D4Mit135 MGI:MGI:92759 +61007 D4Mit172 MGI:MGI:92800 +61008 D4Mit181 MGI:MGI:92810 +61009 D4Mit193 MGI:MGI:92823 +61010 D4Mit211 MGI:MGI:92843 +61011 D4Mit84 MGI:MGI:92920 +61012 D5Mit179 MGI:MGI:93255 +61013 D5Mit193 MGI:MGI:93271 +61014 D5Mit194 MGI:MGI:93272 +61015 D5Mit225 MGI:MGI:93304 +61016 D5Mit226 MGI:MGI:93305 +61017 D6Mit116 MGI:MGI:93542 +61018 D6Mit140 MGI:MGI:93569 +61019 D6Mit158 MGI:MGI:93588 +61020 D6Mit166 MGI:MGI:93597 +61021 D6Mit169 MGI:MGI:93600 +61022 D6Mit170 MGI:MGI:93602 +61023 D6Mit69 MGI:MGI:93701 +61024 D7Mit113 MGI:MGI:93929 +61025 D7Mit143 MGI:MGI:93962 +61026 D7Mit144 MGI:MGI:93963 +61027 D7Mit152 MGI:MGI:93972 +61028 D7Mit178 MGI:MGI:93999 +61029 D7Mit190 MGI:MGI:94013 +61030 D7Mit191 MGI:MGI:94014 +61031 D8Mit123 MGI:MGI:94302 +61032 D8Mit124 MGI:MGI:94303 +61033 D8Mit143 MGI:MGI:94324 +61034 D8Mit155 MGI:MGI:94337 +61035 D8Mit157 MGI:MGI:94339 +61036 D8Mit159 MGI:MGI:94341 +61037 D8Mit170a MGI:MGI:94354 +61038 D9Mit161 MGI:MGI:94671 +61039 DXMit103 MGI:MGI:95063 +61040 DXMit164 MGI:MGI:99984 +61041 DXMit162 MGI:MGI:99986 +61042 DXMit161 MGI:MGI:99987 +61043 DXMit139 MGI:MGI:100009 +61044 DXMit136 MGI:MGI:100012 +61045 DXMit125 MGI:MGI:100023 +61046 DXMit123 MGI:MGI:100025 +61047 D9Mit251 MGI:MGI:100072 +61048 D9Mit223 MGI:MGI:100100 +61049 D9Mit221 MGI:MGI:100102 +61050 D9Mit218 MGI:MGI:100105 +61051 D9Mit217 MGI:MGI:100106 +61052 D8Mit257 MGI:MGI:100153 +61053 D7Mit265 MGI:MGI:100248 +61054 D6Mit260 MGI:MGI:100334 +61055 D5Mit332 MGI:MGI:100384 +61056 D5Mit331 MGI:MGI:100385 +61057 D5Mit294 MGI:MGI:100422 +61058 D5Mit249 MGI:MGI:100467 +61059 D4Mit267 MGI:MGI:100492 +61060 D4Mit266 MGI:MGI:100493 +61061 D4Mit264 MGI:MGI:100495 +61062 D4Mit261 MGI:MGI:100498 +61063 D4Mit235 MGI:MGI:100524 +61064 D4Mit227 MGI:MGI:100532 +61065 D3Mit267 MGI:MGI:100568 +61066 D3Mit265 MGI:MGI:100570 +61067 D3Mit264 MGI:MGI:100571 +61068 D3Mit237 MGI:MGI:100598 +61069 D2Mit362 MGI:MGI:100677 +61070 D2Mit361 MGI:MGI:100678 +61071 D2Mit360 MGI:MGI:100679 +61072 D2Mit357 MGI:MGI:100682 +61073 D2Mit316 MGI:MGI:100723 +61074 D2Mit315 MGI:MGI:100724 +61075 D2Mit313 MGI:MGI:100726 +61076 D2Mit312 MGI:MGI:100727 +61077 D1Mit316 MGI:MGI:101450 +61078 D1Mit296 MGI:MGI:101470 +61079 D2Mit426 MGI:MGI:101994 +61080 D2Mit425 MGI:MGI:101995 +61081 D2Mit428 MGI:MGI:101996 +61082 D3Mit304 MGI:MGI:102028 +61083 D4Mit292 MGI:MGI:102048 +61084 D4Mit293 MGI:MGI:102050 +61085 D5Mit344 MGI:MGI:102071 +61086 D5Mit353 MGI:MGI:102081 +61087 D6Mit308 MGI:MGI:102110 +61088 DXMit187 MGI:MGI:102451 +61089 DXMit191 MGI:MGI:102453 +61090 D7Mit342 MGI:MGI:105486 +61091 D6Mit346 MGI:MGI:105534 +61092 D4Mit316 MGI:MGI:105616 +61093 D4Mit315 MGI:MGI:105617 +61094 D1Mit476 MGI:MGI:105622 +61095 D1Mit478 MGI:MGI:105624 +61096 D1Mit486 MGI:MGI:105632 +61097 D1Mit488 MGI:MGI:105634 +61098 D1Mit489 MGI:MGI:105635 +61099 D1Mit492 MGI:MGI:105638 +61100 D1Mit494 MGI:MGI:105640 +61101 D1Mit495 MGI:MGI:105641 +61102 D1Mit500 MGI:MGI:105646 +61103 D1Mit501 MGI:MGI:105647 +61104 D1Mit505 MGI:MGI:105651 +61105 D1Mit508 MGI:MGI:105654 +61106 D2Mit469 MGI:MGI:105664 +61107 D2Mit472 MGI:MGI:105667 +61108 D2Mit473 MGI:MGI:105668 +61109 D2Mit474 MGI:MGI:105669 +61110 D2Mit480 MGI:MGI:105675 +61111 D2Mit483 MGI:MGI:105678 +61112 D2Mit485 MGI:MGI:105680 +61113 D2Mit488 MGI:MGI:105683 +61114 D2Mit490 MGI:MGI:105685 +61115 D2Mit491 MGI:MGI:105686 +61116 D2Mit492 MGI:MGI:105687 +61117 D2Mit494 MGI:MGI:105689 +61118 D2Mit496 MGI:MGI:105691 +61119 D2Mit499 MGI:MGI:105694 +61120 D2Mit501 MGI:MGI:105696 +61121 D2Mit502 MGI:MGI:105697 +61122 D3Mit348 MGI:MGI:105725 +61123 D3Mit351 MGI:MGI:105728 +61124 D5Mit386 MGI:MGI:105731 +61125 D5Mit387 MGI:MGI:105732 +61126 D5Mit389 MGI:MGI:105734 +61127 D5Mit391 MGI:MGI:105736 +61128 D5Mit395 MGI:MGI:105740 +61129 D5Mit403 MGI:MGI:105748 +61130 D5Mit404 MGI:MGI:105749 +61131 D5Mit405 MGI:MGI:105750 +61132 D5Mit406 MGI:MGI:105751 +61133 D5Mit407 MGI:MGI:105752 +61134 D5Mit408 MGI:MGI:105753 +61135 D5Mit409 MGI:MGI:105754 +61136 D9Mit325 MGI:MGI:105757 +61137 D9Mit328 MGI:MGI:105760 +61138 D9Mit329 MGI:MGI:105761 +61139 D9Mit330 MGI:MGI:105762 +61140 D9Mit334 MGI:MGI:105766 +61141 D9Mit335 MGI:MGI:105767 +61142 D9Mit339 MGI:MGI:105771 +61143 D9Mit346 MGI:MGI:105778 +61144 D9Mit351 MGI:MGI:105783 +61145 DXMit213 MGI:MGI:105906 +61146 D4Mit1006 MGI:MGI:105908 +61147 DXMit220 MGI:MGI:105913 +61148 DXMit221 MGI:MGI:105914 +61149 DXMit223 MGI:MGI:105915 +61150 D10Mit51 MGI:MGI:88835 +61151 D10Mit79 MGI:MGI:88864 +61152 D11Mit1002 MGI:MGI:88867 +61153 D13Mit1000 MGI:MGI:88868 +61154 D11Mit77 MGI:MGI:89156 +61155 D11Mit78 MGI:MGI:89157 +61156 D11Mit8 MGI:MGI:89159 +61157 D12Mit37 MGI:MGI:89447 +61158 D12Mit49 MGI:MGI:89456 +61159 D12Mit56 MGI:MGI:89463 +61160 D12Mit82 MGI:MGI:89492 +61161 D12Mit83 MGI:MGI:89493 +61162 D13Mit17 MGI:MGI:89710 +61163 D13Mit55 MGI:MGI:89782 +61164 D14Mit11 MGI:MGI:89947 +61165 D14Mit51 MGI:MGI:90056 +61166 D15Mit10 MGI:MGI:90228 +61167 D15Mit13 MGI:MGI:90261 +61168 D15Mit80 MGI:MGI:90364 +61169 D16Mit32 MGI:MGI:90501 +61170 D16Mit33 MGI:MGI:90502 +61171 D16Mit55 MGI:MGI:90526 +61172 D16Mit73 MGI:MGI:90546 +61173 D16Mit79 MGI:MGI:90552 +61174 D16Mit88 MGI:MGI:90562 +61175 D17Mit25a MGI:MGI:90813 +61176 D18Mit18 MGI:MGI:91069 +61177 D18Mit21 MGI:MGI:91073 +61178 D18Mit22 MGI:MGI:91074 +61179 D18Mit65 MGI:MGI:91120 +61180 D18Mit66 MGI:MGI:91121 +61181 D18Mit92 MGI:MGI:91150 +61182 D19Mit22 MGI:MGI:91231 +61183 D19Mit29 MGI:MGI:91238 +61184 D19Mit51 MGI:MGI:91263 +61185 D19Mit52 MGI:MGI:91264 +61186 D19Mit56 MGI:MGI:91268 +61187 D19Mit68 MGI:MGI:91281 +61188 D19Mit69 MGI:MGI:91282 +61189 D1Mit103 MGI:MGI:91472 +61190 D1Mit107 MGI:MGI:91476 +61191 D1Mit108 MGI:MGI:91477 +61192 D1Mit109 MGI:MGI:91478 +61193 D1Mit110 MGI:MGI:91480 +61194 D1Mit115 MGI:MGI:91485 +61195 D1Mit119 MGI:MGI:91489 +61196 D1Mit121 MGI:MGI:91492 +61197 D1Mit123 MGI:MGI:91494 +61198 D1Mit124 MGI:MGI:91495 +61199 D1Mit126 MGI:MGI:91497 +61200 D1Mit127 MGI:MGI:91498 +61201 D1Mit128 MGI:MGI:91499 +61202 D1Mit134 MGI:MGI:91506 +61203 D1Mit135 MGI:MGI:91507 +61204 D1Mit136 MGI:MGI:91508 +61205 D1Mit139 MGI:MGI:91511 +61206 D1Mit145 MGI:MGI:91518 +61207 D1Mit163 MGI:MGI:91538 +61208 D1Mit168 MGI:MGI:91543 +61209 D1Mit171 MGI:MGI:91547 +61210 D1Mit172 MGI:MGI:91548 +61211 D1Mit178 MGI:MGI:91554 +61212 D1Mit180 MGI:MGI:91557 +61213 D1Mit181 MGI:MGI:91558 +61214 D1Mit183 MGI:MGI:91560 +61215 D1Mit193 MGI:MGI:91570 +61216 D1Mit194 MGI:MGI:91571 +61217 D1Mit206 MGI:MGI:91585 +61218 D1Mit211 MGI:MGI:91591 +61219 D1Mit212 MGI:MGI:91592 +61220 D1Mit213 MGI:MGI:91593 +61221 D1Mit215 MGI:MGI:91595 +61222 D1Mit216 MGI:MGI:91596 +61223 D1Mit218 MGI:MGI:91598 +61224 D1Mit229 MGI:MGI:91610 +61225 D1Mit230 MGI:MGI:91612 +61226 D1Mit231 MGI:MGI:91613 +61227 D1Mit232 MGI:MGI:91614 +61228 D1Mit233 MGI:MGI:91615 +61229 D1Mit236 MGI:MGI:91618 +61230 D1Mit245 MGI:MGI:91628 +61231 D1Mit247 MGI:MGI:91630 +61232 D1Mit248 MGI:MGI:91631 +61233 D1Mit251 MGI:MGI:91635 +61234 D1Mit257 MGI:MGI:91641 +61235 D1Mit258 MGI:MGI:91642 +61236 D1Mit267 MGI:MGI:91652 +61237 D1Mit270 MGI:MGI:91656 +61238 D1Mit276 MGI:MGI:91662 +61239 D1Mit277 MGI:MGI:91663 +61240 D1Mit279 MGI:MGI:91665 +61241 D3Mit1004 MGI:MGI:91667 +61242 D3Mit1007 MGI:MGI:91670 +61243 D1Mit287 MGI:MGI:91674 +61244 D1Mit288 MGI:MGI:91675 +61245 D1Mit289 MGI:MGI:91676 +61246 D2Mit105 MGI:MGI:91961 +61247 D2Mit108 MGI:MGI:91964 +61248 D2Mit109 MGI:MGI:91965 +61249 D2Mit120 MGI:MGI:91978 +61250 D2Mit123 MGI:MGI:91981 +61251 D2Mit124 MGI:MGI:91982 +61252 D2Mit125 MGI:MGI:91983 +61253 D2Mit126 MGI:MGI:91984 +61254 D2Mit132 MGI:MGI:91991 +61255 D2Mit136 MGI:MGI:91995 +61256 D2Mit138 MGI:MGI:91997 +61257 D2Mit139 MGI:MGI:91998 +61258 D2Mit145 MGI:MGI:92005 +61259 D2Mit151 MGI:MGI:92012 +61260 D2Mit152 MGI:MGI:92013 +61261 D2Mit157 MGI:MGI:92018 +61262 D2Mit159 MGI:MGI:92020 +61263 D2Mit170 MGI:MGI:92033 +61264 D2Mit172 MGI:MGI:92035 +61265 D2Mit181 MGI:MGI:92044 +61266 D2Mit186 MGI:MGI:92049 +61267 D2Mit208 MGI:MGI:92073 +61268 D2Mit212 MGI:MGI:92078 +61269 D2Mit219 MGI:MGI:92085 +61270 D2Mit225 MGI:MGI:92092 +61271 D2Mit229 MGI:MGI:92096 +61272 D2Mit234 MGI:MGI:92101 +61273 D2Mit235 MGI:MGI:92102 +61274 D2Mit240 MGI:MGI:92108 +61275 D2Mit242 MGI:MGI:92110 +61276 D2Mit244 MGI:MGI:92112 +61277 D2Mit245 MGI:MGI:92113 +61278 D2Mit247 MGI:MGI:92115 +61279 D2Mit255 MGI:MGI:92124 +61280 D2Mit256 MGI:MGI:92125 +61281 D2Mit258 MGI:MGI:92127 +61282 D2Mit259 MGI:MGI:92128 +61283 D2Mit260 MGI:MGI:92130 +61284 D2Mit261 MGI:MGI:92131 +61285 D2Mit262 MGI:MGI:92132 +61286 D2Mit268 MGI:MGI:92138 +61287 D2Mit275 MGI:MGI:92146 +61288 D2Mit276 MGI:MGI:92147 +61289 D2Mit278 MGI:MGI:92149 +61290 D2Mit281 MGI:MGI:92153 +61291 D2Mit283 MGI:MGI:92155 +61292 D2Mit284 MGI:MGI:92156 +61293 D2Mit285 MGI:MGI:92157 +61294 D2Mit286 MGI:MGI:92158 +61295 D2Mit287 MGI:MGI:92159 +61296 D2Mit288 MGI:MGI:92160 +61297 D2Mit289 MGI:MGI:92161 +61298 D3Mit101 MGI:MGI:92366 +61299 D3Mit102 MGI:MGI:92367 +61300 D3Mit103 MGI:MGI:92368 +61301 D3Mit105 MGI:MGI:92370 +61302 D3Mit106 MGI:MGI:92371 +61303 D3Mit110 MGI:MGI:92376 +61304 D3Mit114a MGI:MGI:92380 +61305 D3Mit115 MGI:MGI:92381 +61306 D3Mit116 MGI:MGI:92382 +61307 D3Mit119 MGI:MGI:92385 +61308 D3Mit121 MGI:MGI:92388 +61309 D3Mit125 MGI:MGI:92392 +61310 D3Mit137 MGI:MGI:92405 +61311 D3Mit139 MGI:MGI:92407 +61312 D3Mit146 MGI:MGI:92415 +61313 D3Mit147 MGI:MGI:92416 +61314 D3Mit148 MGI:MGI:92417 +61315 D3Mit157 MGI:MGI:92427 +61316 D3Mit159 MGI:MGI:92429 +61317 D3Mit160 MGI:MGI:92431 +61318 D3Mit161a MGI:MGI:92432 +61319 D3Mit163 MGI:MGI:92434 +61320 D3Mit169 MGI:MGI:92440 +61321 D3Mit173 MGI:MGI:92445 +61322 D3Mit175 MGI:MGI:92447 +61323 D3Mit178 MGI:MGI:92450 +61324 D3Mit180 MGI:MGI:92453 +61325 D3Mit182 MGI:MGI:92455 +61326 D3Mit183 MGI:MGI:92456 +61327 D3Mit184 MGI:MGI:92457 +61328 D3Mit188 MGI:MGI:92461 +61329 D3Mit192 MGI:MGI:92466 +61330 D3Mit193 MGI:MGI:92467 +61331 D3Mit194 MGI:MGI:92468 +61332 D3Mit195 MGI:MGI:92469 +61333 D3Mit196 MGI:MGI:92470 +61334 D3Mit197 MGI:MGI:92471 +61335 D3Mit199 MGI:MGI:92473 +61336 D3Mit200 MGI:MGI:92474 +61337 D3Mit201 MGI:MGI:92475 +61338 D3Mit206 MGI:MGI:92480 +61339 D3Mit210 MGI:MGI:92485 +61340 D3Mit213 MGI:MGI:92488 +61341 D3Mit216 MGI:MGI:92491 +61342 D1Mit1000 MGI:MGI:92492 +61343 D3Mit219 MGI:MGI:92494 +61344 D3Mit220 MGI:MGI:92496 +61345 D4Mit110 MGI:MGI:92732 +61346 D4Mit112 MGI:MGI:92734 +61347 D4Mit116 MGI:MGI:92738 +61348 D4Mit120 MGI:MGI:92743 +61349 D4Mit127 MGI:MGI:92750 +61350 D4Mit137 MGI:MGI:92761 +61351 D4Mit145 MGI:MGI:92770 +61352 D4Mit148 MGI:MGI:92773 +61353 D4Mit151 MGI:MGI:92777 +61354 D4Mit152 MGI:MGI:92778 +61355 D4Mit154 MGI:MGI:92780 +61356 D4Mit157 MGI:MGI:92783 +61357 D4Mit158 MGI:MGI:92784 +61358 D4Mit160 MGI:MGI:92787 +61359 D4Mit168 MGI:MGI:92795 +61360 D4Mit175 MGI:MGI:92803 +61361 D4Mit180 MGI:MGI:92809 +61362 D4Mit183 MGI:MGI:92812 +61363 D4Mit186 MGI:MGI:92815 +61364 D4Mit190 MGI:MGI:92820 +61365 D4Mit196 MGI:MGI:92826 +61366 D4Mit197 MGI:MGI:92827 +61367 D4Mit201 MGI:MGI:92832 +61368 D4Mit202 MGI:MGI:92833 +61369 D4Mit203 MGI:MGI:92834 +61370 D4Mit204 MGI:MGI:92835 +61371 D4Mit208 MGI:MGI:92839 +61372 D4Mit209 MGI:MGI:92840 +61373 D4Mit214 MGI:MGI:92846 +61374 D4Mit215 MGI:MGI:92847 +61375 D4Mit219 MGI:MGI:92851 +61376 D5Mit1001 MGI:MGI:92854 +61377 D4Mit223 MGI:MGI:92855 +61378 D4Mit225 MGI:MGI:92857 +61379 D4Mit226 MGI:MGI:92858 +61380 D5Mit100 MGI:MGI:93169 +61381 D5Mit102 MGI:MGI:93171 +61382 D5Mit110 MGI:MGI:93180 +61383 D5Mit117 MGI:MGI:93187 +61384 D5Mit118 MGI:MGI:93188 +61385 D5Mit122 MGI:MGI:93193 +61386 D5Mit124 MGI:MGI:93195 +61387 D5Mit125 MGI:MGI:93196 +61388 D5Mit131 MGI:MGI:93203 +61389 D5Mit132 MGI:MGI:93204 +61390 D5Mit133 MGI:MGI:93205 +61391 D5Mit136 MGI:MGI:93208 +61392 D5Mit138 MGI:MGI:93210 +61393 D5Mit140 MGI:MGI:93213 +61394 D5Mit142 MGI:MGI:93215 +61395 D5Mit143 MGI:MGI:93216 +61396 D5Mit148 MGI:MGI:93221 +61397 D5Mit149 MGI:MGI:93222 +61398 D5Mit151 MGI:MGI:93225 +61399 D5Mit155 MGI:MGI:93229 +61400 D5Mit157 MGI:MGI:93231 +61401 D5Mit158 MGI:MGI:93232 +61402 D5Mit160 MGI:MGI:93235 +61403 D5Mit161 MGI:MGI:93236 +61404 D5Mit165 MGI:MGI:93240 +61405 D5Mit168 MGI:MGI:93243 +61406 D5Mit170 MGI:MGI:93246 +61407 D5Mit171 MGI:MGI:93247 +61408 D5Mit173 MGI:MGI:93249 +61409 D5Mit174 MGI:MGI:93250 +61410 D5Mit175 MGI:MGI:93251 +61411 D5Mit177 MGI:MGI:93253 +61412 D5Mit180 MGI:MGI:93257 +61413 D5Mit182 MGI:MGI:93259 +61414 D5Mit183 MGI:MGI:93260 +61415 D5Mit187 MGI:MGI:93264 +61416 D5Mit188 MGI:MGI:93265 +61417 D5Mit191 MGI:MGI:93269 +61418 D5Mit195 MGI:MGI:93273 +61419 D5Mit202 MGI:MGI:93280 +61420 D5Mit204 MGI:MGI:93282 +61421 D5Mit215 MGI:MGI:93293 +61422 D5Mit221 MGI:MGI:93300 +61423 D5Mit222 MGI:MGI:93301 +61424 D5Mit223 MGI:MGI:93302 +61425 D5Mit224 MGI:MGI:93303 +61426 D5Mit230 MGI:MGI:93310 +61427 D5Mit231 MGI:MGI:93311 +61428 D5Mit233 MGI:MGI:93313 +61429 D5Mit234 MGI:MGI:93314 +61430 D5Mit235 MGI:MGI:93315 +61431 D5Mit237 MGI:MGI:93317 +61432 D5Mit239 MGI:MGI:93319 +61433 D5Mit242 MGI:MGI:93323 +61434 D5Mit243 MGI:MGI:93324 +61435 D5Mit247 MGI:MGI:93328 +61436 D6Mit104 MGI:MGI:93529 +61437 D6Mit105 MGI:MGI:93530 +61438 D6Mit106 MGI:MGI:93531 +61439 D6Mit109 MGI:MGI:93534 +61440 D6Mit113 MGI:MGI:93539 +61441 D6Mit114 MGI:MGI:93540 +61442 D6Mit117 MGI:MGI:93543 +61443 D6Mit119 MGI:MGI:93545 +61444 D6Mit120 MGI:MGI:93547 +61445 D6Mit123 MGI:MGI:93550 +61446 D6Mit125 MGI:MGI:93552 +61447 D6Mit126 MGI:MGI:93553 +61448 D6Mit127 MGI:MGI:93554 +61449 D6Mit132 MGI:MGI:93560 +61450 D6Mit134 MGI:MGI:93562 +61451 D6Mit135 MGI:MGI:93563 +61452 D6Mit143 MGI:MGI:93572 +61453 D6Mit150 MGI:MGI:93580 +61454 D6Mit177 MGI:MGI:93609 +61455 D6Mit178 MGI:MGI:93610 +61456 D6Mit179 MGI:MGI:93611 +61457 D6Mit182 MGI:MGI:93614 +61458 D6Mit183 MGI:MGI:93615 +61459 D6Mit186 MGI:MGI:93618 +61460 D6Mit192 MGI:MGI:93625 +61461 D6Mit196 MGI:MGI:93629 +61462 D6Mit199 MGI:MGI:93632 +61463 D6Mit200 MGI:MGI:93633 +61464 D6Mit201 MGI:MGI:93634 +61465 D6Mit206 MGI:MGI:93639 +61466 D6Mit209 MGI:MGI:93642 +61467 D6Mit212 MGI:MGI:93646 +61468 D7Mit101 MGI:MGI:93917 +61469 D7Mit102 MGI:MGI:93918 +61470 D7Mit103 MGI:MGI:93919 +61471 D7Mit104 MGI:MGI:93920 +61472 D7Mit108 MGI:MGI:93924 +61473 D7Mit109 MGI:MGI:93925 +61474 D7Mit116 MGI:MGI:93932 +61475 D7Mit133 MGI:MGI:93951 +61476 D7Mit134 MGI:MGI:93952 +61477 D7Mit136 MGI:MGI:93954 +61478 D7Mit139 MGI:MGI:93957 +61479 D7Mit140 MGI:MGI:93959 +61480 D7Mit141 MGI:MGI:93960 +61481 D7Mit147 MGI:MGI:93966 +61482 D7Mit149 MGI:MGI:93968 +61483 D7Mit150 MGI:MGI:93970 +61484 D7Mit151 MGI:MGI:93971 +61485 D7Mit155 MGI:MGI:93975 +61486 D7Mit158 MGI:MGI:93978 +61487 D7Mit171 MGI:MGI:93993 +61488 D7Mit175 MGI:MGI:93996 +61489 D7Mit177 MGI:MGI:93998 +61490 D7Mit182 MGI:MGI:94004 +61491 D7Mit184 MGI:MGI:94006 +61492 D7Mit186 MGI:MGI:94008 +61493 D7Mit193 MGI:MGI:94016 +61494 D7Mit195 MGI:MGI:94018 +61495 D7Mit200 MGI:MGI:94024 +61496 D7Mit205 MGI:MGI:94029 +61497 D7Mit207 MGI:MGI:94031 +61498 D7Mit210 MGI:MGI:94035 +61499 D6Mit1000 MGI:MGI:94040 +61500 D7Mit216 MGI:MGI:94041 +61501 D2Mit1009 MGI:MGI:94047 +61502 D7Mit222 MGI:MGI:94048 +61503 D8Mit100 MGI:MGI:94277 +61504 D8Mit106 MGI:MGI:94283 +61505 D8Mit109 MGI:MGI:94286 +61506 D8Mit110 MGI:MGI:94288 +61507 D8Mit111 MGI:MGI:94289 +61508 D8Mit113 MGI:MGI:94291 +61509 D8Mit117 MGI:MGI:94295 +61510 D8Mit122 MGI:MGI:94301 +61511 D8Mit125 MGI:MGI:94304 +61512 D8Mit126 MGI:MGI:94305 +61513 D8Mit127 MGI:MGI:94306 +61514 D8Mit130 MGI:MGI:94310 +61515 D8Mit137 MGI:MGI:94317 +61516 D8Mit138 MGI:MGI:94318 +61517 D8Mit139 MGI:MGI:94319 +61518 D8Mit148 MGI:MGI:94329 +61519 D8Mit151 MGI:MGI:94333 +61520 D8Mit152 MGI:MGI:94334 +61521 D8Mit156 MGI:MGI:94338 +61522 D8Mit162 MGI:MGI:94345 +61523 D8Mit165 MGI:MGI:94348 +61524 D8Mit169 MGI:MGI:94352 +61525 D8Mit182 MGI:MGI:94366 +61526 D8Mit183 MGI:MGI:94367 +61527 D8Mit185 MGI:MGI:94369 +61528 D8Mit186 MGI:MGI:94370 +61529 D8Mit188 MGI:MGI:94372 +61530 D8Mit189 MGI:MGI:94373 +61531 D8Mit191 MGI:MGI:94375 +61532 D8Mit192 MGI:MGI:94376 +61533 D8Mit198 MGI:MGI:94382 +61534 D8Mit200 MGI:MGI:94385 +61535 D8Mit201 MGI:MGI:94386 +61536 D9Mit100 MGI:MGI:94612 +61537 D9Mit105 MGI:MGI:94614 +61538 D9Mit115 MGI:MGI:94622 +61539 D9Mit117 MGI:MGI:94624 +61540 D9Mit118 MGI:MGI:94625 +61541 D9Mit120 MGI:MGI:94628 +61542 D9Mit128 MGI:MGI:94635 +61543 D9Mit130 MGI:MGI:94637 +61544 D9Mit133 MGI:MGI:94640 +61545 D9Mit137 MGI:MGI:94644 +61546 D9Mit140 MGI:MGI:94648 +61547 D9Mit141 MGI:MGI:94649 +61548 D9Mit143 MGI:MGI:94651 +61549 D9Mit144 MGI:MGI:94652 +61550 D9Mit150 MGI:MGI:94659 +61551 D9Mit151 MGI:MGI:94660 +61552 D9Mit152 MGI:MGI:94661 +61553 D9Mit154 MGI:MGI:94663 +61554 D9Mit157 MGI:MGI:94666 +61555 D9Mit164 MGI:MGI:94674 +61556 D9Mit169 MGI:MGI:94679 +61557 D9Mit175 MGI:MGI:94685 +61558 D9Mit177a MGI:MGI:94687 +61559 D9Mit181 MGI:MGI:94692 +61560 D9Mit182 MGI:MGI:94693 +61561 D9Mit199 MGI:MGI:94711 +61562 DXMit100 MGI:MGI:95060 +61563 DXMit104 MGI:MGI:95064 +61564 DXMit109 MGI:MGI:95069 +61565 DXMit113a MGI:MGI:95074 +61566 DXMit114 MGI:MGI:95075 +61567 DXMit116 MGI:MGI:95077 +61568 DXMit117 MGI:MGI:95078 +61569 DXMit121 MGI:MGI:95083 +61570 DXMit186 MGI:MGI:99962 +61571 DXMit182 MGI:MGI:99966 +61572 DXMit180 MGI:MGI:99968 +61573 DXMit178 MGI:MGI:99970 +61574 DXMit176 MGI:MGI:99972 +61575 DXMit175 MGI:MGI:99973 +61576 DXMit174 MGI:MGI:99974 +61577 DXMit170 MGI:MGI:99978 +61578 DXMit157 MGI:MGI:99991 +61579 DXMit150 MGI:MGI:99998 +61580 DXMit143 MGI:MGI:100005 +61581 DXMit140 MGI:MGI:100008 +61582 DXMit135 MGI:MGI:100013 +61583 DXMit132 MGI:MGI:100016 +61584 DXMit129 MGI:MGI:100019 +61585 DXMit128 MGI:MGI:100020 +61586 DXMit126 MGI:MGI:100022 +61587 D9Mit293 MGI:MGI:100030 +61588 D9Mit290 MGI:MGI:100033 +61589 D9Mit289 MGI:MGI:100034 +61590 D9Mit286 MGI:MGI:100037 +61591 D9Mit285 MGI:MGI:100038 +61592 D9Mit281 MGI:MGI:100042 +61593 D9Mit280 MGI:MGI:100043 +61594 D9Mit279 MGI:MGI:100044 +61595 D9Mit278 MGI:MGI:100045 +61596 D9Mit277 MGI:MGI:100046 +61597 D9Mit276 MGI:MGI:100047 +61598 D9Mit272 MGI:MGI:100051 +61599 D9Mit271 MGI:MGI:100052 +61600 D9Mit270 MGI:MGI:100053 +61601 D9Mit266 MGI:MGI:100057 +61602 D9Mit264 MGI:MGI:100059 +61603 D9Mit263 MGI:MGI:100060 +61604 D9Mit261 MGI:MGI:100062 +61605 D9Mit259 MGI:MGI:100064 +61606 D9Mit256 MGI:MGI:100067 +61607 D9Mit253 MGI:MGI:100070 +61608 D9Mit247 MGI:MGI:100076 +61609 D9Mit245 MGI:MGI:100078 +61610 D9Mit242 MGI:MGI:100081 +61611 D9Mit239 MGI:MGI:100084 +61612 D9Mit230 MGI:MGI:100093 +61613 D9Mit227 MGI:MGI:100096 +61614 D9Mit215 MGI:MGI:100108 +61615 D9Mit214 MGI:MGI:100109 +61616 D9Mit205 MGI:MGI:100118 +61617 D8Mit284 MGI:MGI:100126 +61618 D8Mit281 MGI:MGI:100129 +61619 D8Mit280 MGI:MGI:100130 +61620 D8Mit277 MGI:MGI:100133 +61621 D8Mit275 MGI:MGI:100135 +61622 D8Mit274 MGI:MGI:100136 +61623 D8Mit271 MGI:MGI:100139 +61624 D8Mit270 MGI:MGI:100140 +61625 D8Mit264 MGI:MGI:100146 +61626 D8Mit262 MGI:MGI:100148 +61627 D8Mit259 MGI:MGI:100151 +61628 D8Mit252 MGI:MGI:100158 +61629 D8Mit251 MGI:MGI:100159 +61630 D8Mit250 MGI:MGI:100160 +61631 D8Mit246 MGI:MGI:100164 +61632 D8Mit244 MGI:MGI:100166 +61633 D8Mit242 MGI:MGI:100168 +61634 D8Mit241 MGI:MGI:100169 +61635 D8Mit240 MGI:MGI:100170 +61636 D8Mit239 MGI:MGI:100171 +61637 D8Mit236 MGI:MGI:100174 +61638 D8Mit233 MGI:MGI:100177 +61639 D8Mit232 MGI:MGI:100178 +61640 D8Mit231 MGI:MGI:100179 +61641 D8Mit230 MGI:MGI:100180 +61642 D8Mit229 MGI:MGI:100181 +61643 D8Mit228 MGI:MGI:100182 +61644 D8Mit227 MGI:MGI:100183 +61645 D8Mit213 MGI:MGI:100197 +61646 D8Mit211 MGI:MGI:100199 +61647 D8Mit205 MGI:MGI:100205 +61648 D8Mit204 MGI:MGI:100206 +61649 D7Mit304 MGI:MGI:100209 +61650 D7Mit301 MGI:MGI:100212 +61651 D7Mit300 MGI:MGI:100213 +61652 D7Mit288 MGI:MGI:100225 +61653 D7Mit287 MGI:MGI:100226 +61654 D7Mit285 MGI:MGI:100228 +61655 D7Mit281 MGI:MGI:100232 +61656 D7Mit276 MGI:MGI:100237 +61657 D7Mit274 MGI:MGI:100239 +61658 D7Mit270 MGI:MGI:100243 +61659 D7Mit267 MGI:MGI:100246 +61660 D7Mit261 MGI:MGI:100252 +61661 D7Mit260 MGI:MGI:100253 +61662 D7Mit255 MGI:MGI:100258 +61663 D7Mit242 MGI:MGI:100271 +61664 D7Mit233 MGI:MGI:100280 +61665 D7Mit230 MGI:MGI:100283 +61666 D7Mit228 MGI:MGI:100285 +61667 D7Mit227 MGI:MGI:100286 +61668 D7Mit226 MGI:MGI:100287 +61669 D6Mit304 MGI:MGI:100290 +61670 D6Mit301 MGI:MGI:100293 +61671 D6Mit300 MGI:MGI:100294 +61672 D6Mit296 MGI:MGI:100298 +61673 D6Mit295 MGI:MGI:100299 +61674 D6Mit294 MGI:MGI:100300 +61675 D6Mit292 MGI:MGI:100302 +61676 D6Mit291 MGI:MGI:100303 +61677 D6Mit289 MGI:MGI:100305 +61678 D6Mit287 MGI:MGI:100307 +61679 D6Mit284 MGI:MGI:100310 +61680 D6Mit282 MGI:MGI:100312 +61681 D6Mit280 MGI:MGI:100314 +61682 D6Mit278 MGI:MGI:100316 +61683 D6Mit277 MGI:MGI:100317 +61684 D6Mit273 MGI:MGI:100321 +61685 D6Mit271 MGI:MGI:100323 +61686 D6Mit269 MGI:MGI:100325 +61687 D6Mit262 MGI:MGI:100332 +61688 D6Mit258 MGI:MGI:100336 +61689 D6Mit252 MGI:MGI:100342 +61690 D6Mit245 MGI:MGI:100349 +61691 D6Mit244 MGI:MGI:100350 +61692 D6Mit243 MGI:MGI:100351 +61693 D6Mit241 MGI:MGI:100353 +61694 D6Mit231 MGI:MGI:100363 +61695 D6Mit230 MGI:MGI:100364 +61696 D6Mit229 MGI:MGI:100365 +61697 D6Mit224 MGI:MGI:100370 +61698 D6Mit223 MGI:MGI:100371 +61699 D5Mit341 MGI:MGI:100375 +61700 D5Mit339 MGI:MGI:100377 +61701 D5Mit338 MGI:MGI:100378 +61702 D5Mit334 MGI:MGI:100382 +61703 D5Mit329 MGI:MGI:100387 +61704 D5Mit328 MGI:MGI:100388 +61705 D5Mit326 MGI:MGI:100390 +61706 D5Mit324 MGI:MGI:100392 +61707 D5Mit320 MGI:MGI:100396 +61708 D5Mit319 MGI:MGI:100397 +61709 D5Mit318 MGI:MGI:100398 +61710 D5Mit317 MGI:MGI:100399 +61711 D5Mit315 MGI:MGI:100401 +61712 D5Mit314 MGI:MGI:100402 +61713 D5Mit312 MGI:MGI:100404 +61714 D5Mit309 MGI:MGI:100407 +61715 D5Mit308 MGI:MGI:100408 +61716 D5Mit307 MGI:MGI:100409 +61717 D5Mit305 MGI:MGI:100411 +61718 D5Mit302 MGI:MGI:100414 +61719 D5Mit300 MGI:MGI:100416 +61720 D5Mit298 MGI:MGI:100418 +61721 D5Mit292 MGI:MGI:100424 +61722 D5Mit287 MGI:MGI:100429 +61723 D5Mit284 MGI:MGI:100432 +61724 D5Mit282 MGI:MGI:100434 +61725 D5Mit281 MGI:MGI:100435 +61726 D5Mit278 MGI:MGI:100438 +61727 D5Mit274 MGI:MGI:100442 +61728 D5Mit267 MGI:MGI:100449 +61729 D5Mit264 MGI:MGI:100452 +61730 D5Mit263 MGI:MGI:100453 +61731 D5Mit261 MGI:MGI:100455 +61732 D5Mit255 MGI:MGI:100461 +61733 D4Mit290 MGI:MGI:100469 +61734 D4Mit289 MGI:MGI:100470 +61735 D4Mit287 MGI:MGI:100472 +61736 D4Mit286 MGI:MGI:100473 +61737 D4Mit284 MGI:MGI:100475 +61738 D4Mit281 MGI:MGI:100478 +61739 D4Mit278 MGI:MGI:100481 +61740 D4Mit277 MGI:MGI:100482 +61741 D4Mit276 MGI:MGI:100483 +61742 D4Mit274 MGI:MGI:100485 +61743 D4Mit273 MGI:MGI:100486 +61744 D4Mit272 MGI:MGI:100487 +61745 D4Mit270 MGI:MGI:100489 +61746 D4Mit269 MGI:MGI:100490 +61747 D4Mit258 MGI:MGI:100501 +61748 D4Mit257 MGI:MGI:100502 +61749 D4Mit254 MGI:MGI:100505 +61750 D4Mit253 MGI:MGI:100506 +61751 D4Mit252 MGI:MGI:100507 +61752 D4Mit251 MGI:MGI:100508 +61753 D4Mit250a MGI:MGI:100509 +61754 D4Mit249 MGI:MGI:100510 +61755 D4Mit248 MGI:MGI:100511 +61756 D4Mit241 MGI:MGI:100518 +61757 D4Mit238 MGI:MGI:100521 +61758 D4Mit237a MGI:MGI:100522 +61759 D4Mit236 MGI:MGI:100523 +61760 D4Mit231 MGI:MGI:100528 +61761 D4Mit229 MGI:MGI:100530 +61762 D4Mit228 MGI:MGI:100531 +61763 D3Mit295 MGI:MGI:100540 +61764 D3Mit293 MGI:MGI:100542 +61765 D3Mit292 MGI:MGI:100543 +61766 D3Mit286 MGI:MGI:100549 +61767 D3Mit284 MGI:MGI:100551 +61768 D3Mit282 MGI:MGI:100553 +61769 D3Mit280 MGI:MGI:100555 +61770 D3Mit278 MGI:MGI:100557 +61771 D3Mit277 MGI:MGI:100558 +61772 D3Mit275 MGI:MGI:100560 +61773 D3Mit274 MGI:MGI:100561 +61774 D3Mit273 MGI:MGI:100562 +61775 D3Mit262 MGI:MGI:100573 +61776 D3Mit261 MGI:MGI:100574 +61777 D3Mit259 MGI:MGI:100576 +61778 D3Mit258 MGI:MGI:100577 +61779 D3Mit255 MGI:MGI:100580 +61780 D3Mit252 MGI:MGI:100583 +61781 D3Mit250 MGI:MGI:100585 +61782 D3Mit245 MGI:MGI:100590 +61783 D3Mit244 MGI:MGI:100591 +61784 D3Mit241 MGI:MGI:100594 +61785 D3Mit239 MGI:MGI:100596 +61786 D3Mit238 MGI:MGI:100597 +61787 D3Mit234 MGI:MGI:100601 +61788 D3Mit233 MGI:MGI:100602 +61789 D3Mit228 MGI:MGI:100607 +61790 D3Mit222 MGI:MGI:100613 +61791 D2Mit424 MGI:MGI:100615 +61792 D2Mit423 MGI:MGI:100616 +61793 D2Mit422 MGI:MGI:100617 +61794 D2Mit420 MGI:MGI:100619 +61795 D2Mit417 MGI:MGI:100622 +61796 D2Mit416 MGI:MGI:100623 +61797 D2Mit411 MGI:MGI:100628 +61798 D2Mit409 MGI:MGI:100630 +61799 D2Mit408 MGI:MGI:100631 +61800 D2Mit403 MGI:MGI:100636 +61801 D2Mit400 MGI:MGI:100639 +61802 D2Mit398 MGI:MGI:100641 +61803 D2Mit396 MGI:MGI:100643 +61804 D2Mit395 MGI:MGI:100644 +61805 D2Mit390 MGI:MGI:100649 +61806 D2Mit383 MGI:MGI:100656 +61807 D2Mit382 MGI:MGI:100657 +61808 D2Mit381 MGI:MGI:100658 +61809 D2Mit380 MGI:MGI:100659 +61810 D2Mit376 MGI:MGI:100663 +61811 D2Mit374 MGI:MGI:100665 +61812 D2Mit372 MGI:MGI:100667 +61813 D2Mit370 MGI:MGI:100669 +61814 D2Mit368 MGI:MGI:100671 +61815 D2Mit367 MGI:MGI:100672 +61816 D2Mit364 MGI:MGI:100675 +61817 D2Mit354 MGI:MGI:100685 +61818 D2Mit353 MGI:MGI:100686 +61819 D2Mit349 MGI:MGI:100690 +61820 D2Mit346 MGI:MGI:100693 +61821 D2Mit345 MGI:MGI:100694 +61822 D2Mit343 MGI:MGI:100696 +61823 D2Mit342 MGI:MGI:100697 +61824 D2Mit339 MGI:MGI:100700 +61825 D2Mit338 MGI:MGI:100701 +61826 D2Mit337 MGI:MGI:100702 +61827 D2Mit333 MGI:MGI:100706 +61828 D2Mit328 MGI:MGI:100711 +61829 D2Mit324 MGI:MGI:100715 +61830 D2Mit322 MGI:MGI:100717 +61831 D2Mit321 MGI:MGI:100718 +61832 D2Mit318 MGI:MGI:100721 +61833 D2Mit311 MGI:MGI:100728 +61834 D2Mit309 MGI:MGI:100730 +61835 D2Mit307 MGI:MGI:100732 +61836 D2Mit304 MGI:MGI:100735 +61837 D2Mit296 MGI:MGI:100743 +61838 D2Mit295 MGI:MGI:100744 +61839 D2Mit294 MGI:MGI:100745 +61840 D19Mit94 MGI:MGI:100753 +61841 D19Mit78 MGI:MGI:100769 +61842 D19Mit77 MGI:MGI:100770 +61843 D1Mit425 MGI:MGI:101341 +61844 D1Mit417 MGI:MGI:101349 +61845 D1Mit415 MGI:MGI:101351 +61846 D1Mit412 MGI:MGI:101354 +61847 D1Mit411 MGI:MGI:101355 +61848 D1Mit410 MGI:MGI:101356 +61849 D1Mit401 MGI:MGI:101365 +61850 D1Mit400 MGI:MGI:101366 +61851 D1Mit399 MGI:MGI:101367 +61852 D1Mit396 MGI:MGI:101370 +61853 D1Mit391 MGI:MGI:101375 +61854 D1Mit386 MGI:MGI:101380 +61855 D1Mit385 MGI:MGI:101381 +61856 D1Mit384 MGI:MGI:101382 +61857 D1Mit381a MGI:MGI:101385 +61858 D1Mit374 MGI:MGI:101392 +61859 D1Mit373 MGI:MGI:101393 +61860 D1Mit372a MGI:MGI:101394 +61861 D1Mit370 MGI:MGI:101396 +61862 D1Mit369 MGI:MGI:101397 +61863 D1Mit366 MGI:MGI:101400 +61864 D1Mit365 MGI:MGI:101401 +61865 D1Mit363 MGI:MGI:101403 +61866 D1Mit354 MGI:MGI:101412 +61867 D1Mit353 MGI:MGI:101413 +61868 D1Mit352 MGI:MGI:101414 +61869 D1Mit350 MGI:MGI:101416 +61870 D1Mit348 MGI:MGI:101418 +61871 D1Mit345 MGI:MGI:101421 +61872 D1Mit338 MGI:MGI:101428 +61873 D1Mit336 MGI:MGI:101430 +61874 D1Mit334 MGI:MGI:101432 +61875 D1Mit333 MGI:MGI:101433 +61876 D1Mit332 MGI:MGI:101434 +61877 D1Mit331 MGI:MGI:101435 +61878 D1Mit330 MGI:MGI:101436 +61879 D1Mit328 MGI:MGI:101438 +61880 D1Mit325 MGI:MGI:101441 +61881 D1Mit324 MGI:MGI:101442 +61882 D1Mit322 MGI:MGI:101444 +61883 D1Mit320 MGI:MGI:101446 +61884 D1Mit318 MGI:MGI:101448 +61885 D1Mit314 MGI:MGI:101452 +61886 D1Mit306 MGI:MGI:101460 +61887 D1Mit305 MGI:MGI:101461 +61888 D1Mit298 MGI:MGI:101468 +61889 D1Mit430 MGI:MGI:101959 +61890 D1Mit431 MGI:MGI:101960 +61891 D1Mit432 MGI:MGI:101961 +61892 D1Mit433 MGI:MGI:101962 +61893 D1Mit439 MGI:MGI:101967 +61894 D1Mit440 MGI:MGI:101969 +61895 D1Mit441 MGI:MGI:101970 +61896 D1Mit453 MGI:MGI:101982 +61897 D1Mit456 MGI:MGI:101985 +61898 D2Mit433 MGI:MGI:102002 +61899 D2Mit434 MGI:MGI:102003 +61900 D2Mit435 MGI:MGI:102004 +61901 D2Mit436 MGI:MGI:102005 +61902 D2Mit443 MGI:MGI:102012 +61903 D2Mit444 MGI:MGI:102013 +61904 D2Mit447 MGI:MGI:102016 +61905 D2Mit448 MGI:MGI:102017 +61906 D2Mit449 MGI:MGI:102018 +61907 D2Mit450 MGI:MGI:102019 +61908 D2Mit451 MGI:MGI:102020 +61909 D2Mit453 MGI:MGI:102021 +61910 D2Mit455 MGI:MGI:102023 +61911 D2Mit456 MGI:MGI:102025 +61912 D3Mit305 MGI:MGI:102029 +61913 D4Mit295 MGI:MGI:102052 +61914 D4Mit297 MGI:MGI:102054 +61915 D4Mit298 MGI:MGI:102055 +61916 D4Mit299 MGI:MGI:102056 +61917 D4Mit300 MGI:MGI:102057 +61918 D4Mit302 MGI:MGI:102058 +61919 D4Mit303 MGI:MGI:102060 +61920 D4Mit304 MGI:MGI:102061 +61921 D4Mit306 MGI:MGI:102063 +61922 D4Mit309 MGI:MGI:102066 +61923 D4Mit310 MGI:MGI:102068 +61924 D4Mit313 MGI:MGI:102070 +61925 D5Mit350 MGI:MGI:102078 +61926 D5Mit354 MGI:MGI:102082 +61927 D5Mit357 MGI:MGI:102086 +61928 D5Mit364 MGI:MGI:102091 +61929 D5Mit365 MGI:MGI:102093 +61930 D5Mit366 MGI:MGI:102094 +61931 D5Mit367 MGI:MGI:102095 +61932 D5Mit368 MGI:MGI:102096 +61933 D5Mit369 MGI:MGI:102097 +61934 D5Mit372 MGI:MGI:102100 +61935 D5Mit374 MGI:MGI:102102 +61936 D5Mit375 MGI:MGI:102103 +61937 D5Mit376 MGI:MGI:102104 +61938 D5Mit377 MGI:MGI:102105 +61939 D5Mit378 MGI:MGI:102106 +61940 D6Mit309 MGI:MGI:102112 +61941 D6Mit310 MGI:MGI:102113 +61942 D6Mit311 MGI:MGI:102114 +61943 D6Mit316 MGI:MGI:102119 +61944 D6Mit322 MGI:MGI:102125 +61945 D6Mit323 MGI:MGI:102126 +61946 D6Mit325 MGI:MGI:102128 +61947 D6Mit326 MGI:MGI:102129 +61948 D6Mit328 MGI:MGI:102131 +61949 D6Mit329 MGI:MGI:102132 +61950 D6Mit331 MGI:MGI:102133 +61951 D6Mit330 MGI:MGI:102135 +61952 D6Mit339 MGI:MGI:102142 +61953 D6Mit340 MGI:MGI:102143 +61954 D7Mit311a MGI:MGI:102150 +61955 D7Mit312 MGI:MGI:102151 +61956 D7Mit313 MGI:MGI:102152 +61957 D7Mit321 MGI:MGI:102160 +61958 D7Mit326 MGI:MGI:102163 +61959 D7Mit328 MGI:MGI:102167 +61960 D7Mit330 MGI:MGI:102169 +61961 D8Mit290 MGI:MGI:102178 +61962 D8Mit291 MGI:MGI:102180 +61963 D8Mit293 MGI:MGI:102182 +61964 D8Mit296 MGI:MGI:102185 +61965 D8Mit297 MGI:MGI:102186 +61966 D8Mit298 MGI:MGI:102187 +61967 D8Mit300 MGI:MGI:102188 +61968 D8Mit302 MGI:MGI:102191 +61969 D8Mit304 MGI:MGI:102193 +61970 D8Mit307 MGI:MGI:102198 +61971 D8Mit311 MGI:MGI:102201 +61972 D8Mit313 MGI:MGI:102203 +61973 D8Mit314 MGI:MGI:102205 +61974 D8Mit318 MGI:MGI:102207 +61975 D8Mit317 MGI:MGI:102208 +61976 D8Mit319 MGI:MGI:102209 +61977 D8Mit323 MGI:MGI:102213 +61978 D8Mit324 MGI:MGI:102214 +61979 D8Mit325 MGI:MGI:102215 +61980 D8Mit326 MGI:MGI:102216 +61981 D9Mit297 MGI:MGI:102220 +61982 D9Mit298 MGI:MGI:102221 +61983 D9Mit299 MGI:MGI:102223 +61984 D9Mit301 MGI:MGI:102227 +61985 D9Mit312 MGI:MGI:102228 +61986 D9Mit304 MGI:MGI:102231 +61987 D9Mit307 MGI:MGI:102234 +61988 D9Mit114 MGI:MGI:102236 +61989 D9Mit310 MGI:MGI:102237 +61990 D9Mit311 MGI:MGI:102239 +61991 D9Mit121 MGI:MGI:102240 +61992 DXMit196 MGI:MGI:102460 +61993 DXMit189 MGI:MGI:102461 +61994 D4Mit339 MGI:MGI:104340 +61995 D8Mit352 MGI:MGI:105445 +61996 D8Mit349 MGI:MGI:105448 +61997 D8Mit348 MGI:MGI:105449 +61998 D8Mit347 MGI:MGI:105450 +61999 D8Mit346 MGI:MGI:105451 +62000 D8Mit345 MGI:MGI:105452 +62001 D8Mit342 MGI:MGI:105455 +62002 D8Mit339 MGI:MGI:105458 +62003 D8Mit336 MGI:MGI:105461 +62004 D7Mit362 MGI:MGI:105466 +62005 D7Mit361 MGI:MGI:105467 +62006 D7Mit357 MGI:MGI:105471 +62007 D7Mit344 MGI:MGI:105484 +62008 D7Mit343 MGI:MGI:105485 +62009 D6Mit374a MGI:MGI:105506 +62010 D6Mit373 MGI:MGI:105507 +62011 D6Mit372 MGI:MGI:105508 +62012 D6Mit368 MGI:MGI:105512 +62013 D6Mit366 MGI:MGI:105514 +62014 D6Mit355 MGI:MGI:105525 +62015 D6Mit352 MGI:MGI:105528 +62016 D4Mit344 MGI:MGI:105589 +62017 D4Mit342 MGI:MGI:105591 +62018 D4Mit338 MGI:MGI:105594 +62019 D4Mit336 MGI:MGI:105596 +62020 D4Mit332 MGI:MGI:105600 +62021 D4Mit328 MGI:MGI:105604 +62022 D4Mit325 MGI:MGI:105607 +62023 D4Mit320 MGI:MGI:105612 +62024 D4Mit319 MGI:MGI:105613 +62025 D1Mit509 MGI:MGI:105655 +62026 D1Mit512 MGI:MGI:105658 +62027 D4Mit1005 MGI:MGI:105702 +62028 D1Mit526 MGI:MGI:107035 +62029 D1Mit531 MGI:MGI:107041 +62030 D1Mit538 MGI:MGI:107048 +62031 D1Mit541 MGI:MGI:107052 +62032 D2Mit521 MGI:MGI:107069 +62033 D2Mit522 MGI:MGI:107070 +62034 D2Mit523 MGI:MGI:107071 +62035 D2Mit524 MGI:MGI:107072 +62036 D4Mit348 MGI:MGI:107086 +62037 D4Mit356 MGI:MGI:107094 +62038 D5Mit424 MGI:MGI:107102 +62039 D5Mit425 MGI:MGI:107103 +62040 D5Mit426 MGI:MGI:107104 +62041 D6Mit384 MGI:MGI:107108 +62042 D6Mit388 MGI:MGI:107112 +62043 D6Mit389 MGI:MGI:107113 +62044 D8Mit359 MGI:MGI:107128 +62045 D9Mit355 MGI:MGI:107137 +62046 D9Mit357 MGI:MGI:107139 +62047 DXMit229 MGI:MGI:107147 +62048 DXMit230 MGI:MGI:107148 +62049 DXMit231 MGI:MGI:107149 +62050 DXMit232 MGI:MGI:107150 +62051 DXMit234 MGI:MGI:107152 +62052 DXMit236 MGI:MGI:107154 +62053 D4Mit361 MGI:MGI:703073 +62054 D5Mit431 MGI:MGI:704519 +62055 D6Mit391 MGI:MGI:706642 +62056 D3Mit370 MGI:MGI:707243 +62057 DXMit249 MGI:MGI:707611 +62058 D10Mit12 MGI:MGI:88737 +62059 D10Mit13 MGI:MGI:88748 +62060 D10Mit14 MGI:MGI:88759 +62061 D10Mit16 MGI:MGI:88780 +62062 D10Mit17 MGI:MGI:88791 +62063 D10Mit33 MGI:MGI:88817 +62064 D10Mit34 MGI:MGI:88818 +62065 D10Mit35a MGI:MGI:88819 +62066 D10Mit41 MGI:MGI:88824 +62067 D10Mit42 MGI:MGI:88825 +62068 D10Mit45 MGI:MGI:88828 +62069 D10Mit46 MGI:MGI:88829 +62070 D10Mit47 MGI:MGI:88830 +62071 D10Mit53 MGI:MGI:88837 +62072 D10Mit54 MGI:MGI:88838 +62073 D10Mit55 MGI:MGI:88839 +62074 D10Mit57 MGI:MGI:88841 +62075 D10Mit59 MGI:MGI:88843 +62076 D10Mit61 MGI:MGI:88845 +62077 D10Mit62 MGI:MGI:88846 +62078 D10Mit63 MGI:MGI:88847 +62079 D10Mit64 MGI:MGI:88848 +62080 D10Mit65 MGI:MGI:88849 +62081 D10Mit66 MGI:MGI:88850 +62082 D10Mit68 MGI:MGI:88852 +62083 D10Mit69 MGI:MGI:88853 +62084 D10Mit70 MGI:MGI:88855 +62085 D10Mit71 MGI:MGI:88856 +62086 D10Mit74 MGI:MGI:88859 +62087 D10Mit87 MGI:MGI:88873 +62088 D10Mit94 MGI:MGI:88881 +62089 D10Mit96 MGI:MGI:88883 +62090 D10Mit97 MGI:MGI:88884 +62091 D10Mit98 MGI:MGI:88885 +62092 D11Mit11 MGI:MGI:88990 +62093 D11Mit14 MGI:MGI:89023 +62094 D11Mit22 MGI:MGI:89105 +62095 D11Mit51 MGI:MGI:89131 +62096 D11Mit61 MGI:MGI:89139 +62097 D11Mit72 MGI:MGI:89151 +62098 D11Mit79 MGI:MGI:89158 +62099 D11Mit81 MGI:MGI:89161 +62100 D11Mit84 MGI:MGI:89164 +62101 D11Mit87 MGI:MGI:89167 +62102 D11Mit90 MGI:MGI:89170 +62103 D11Mit91 MGI:MGI:89171 +62104 D11Mit98 MGI:MGI:89178 +62105 D11Mit99 MGI:MGI:89179 +62106 D12Mit51 MGI:MGI:89459 +62107 D12Mit54 MGI:MGI:89462 +62108 D12Mit60 MGI:MGI:89468 +62109 D1Mit1008 MGI:MGI:89471 +62110 D12Mit64 MGI:MGI:89472 +62111 D12Mit66 MGI:MGI:89474 +62112 D12Mit74 MGI:MGI:89483 +62113 D12Mit76 MGI:MGI:89485 +62114 D12Mit77 MGI:MGI:89486 +62115 D12Mit80 MGI:MGI:89490 +62116 D12Mit87 MGI:MGI:89497 +62117 D12Mit88 MGI:MGI:89498 +62118 D12Mit92 MGI:MGI:89503 +62119 D17Mit1007 MGI:MGI:89504 +62120 D12Mit96 MGI:MGI:89507 +62121 D12Mit97 MGI:MGI:89508 +62122 D12Mit98 MGI:MGI:89509 +62123 D12Mit99 MGI:MGI:89510 +62124 D13Mit13 MGI:MGI:89667 +62125 D13Mit16 MGI:MGI:89700 +62126 D13Mit18 MGI:MGI:89721 +62127 D13Mit32 MGI:MGI:89760 +62128 D13Mit35 MGI:MGI:89762 +62129 D13Mit38 MGI:MGI:89765 +62130 D2Mit1003 MGI:MGI:89768 +62131 D13Mit47 MGI:MGI:89773 +62132 D13Mit52 MGI:MGI:89779 +62133 D13Mit61 MGI:MGI:89788 +62134 D13Mit63 MGI:MGI:89790 +62135 D13Mit65 MGI:MGI:89792 +62136 D13Mit66 MGI:MGI:89793 +62137 D13Mit69 MGI:MGI:89796 +62138 D13Mit70 MGI:MGI:89798 +62139 D13Mit71 MGI:MGI:89799 +62140 D13Mit72 MGI:MGI:89800 +62141 D13Mit76 MGI:MGI:89804 +62142 D13Mit78 MGI:MGI:89806 +62143 D13Mit79 MGI:MGI:89807 +62144 D13Mit85 MGI:MGI:89814 +62145 D13Mit86 MGI:MGI:89815 +62146 D13Mit87 MGI:MGI:89816 +62147 D13Mit89 MGI:MGI:89818 +62148 D13Mit90 MGI:MGI:89820 +62149 D13Mit91 MGI:MGI:89821 +62150 D13Mit94 MGI:MGI:89824 +62151 D13Mit95 MGI:MGI:89825 +62152 D13Mit99 MGI:MGI:89829 +62153 D14Mit15 MGI:MGI:89991 +62154 D14Mit31 MGI:MGI:90035 +62155 D14Mit37 MGI:MGI:90041 +62156 D14Mit38 MGI:MGI:90042 +62157 D14Mit39 MGI:MGI:90043 +62158 D14Mit45 MGI:MGI:90049 +62159 D14Mit53 MGI:MGI:90058 +62160 D14Mit56 MGI:MGI:90061 +62161 D14Mit59 MGI:MGI:90064 +62162 D14Mit60 MGI:MGI:90066 +62163 D14Mit61 MGI:MGI:90067 +62164 D14Mit62 MGI:MGI:90068 +62165 D14Mit63 MGI:MGI:90069 +62166 D14Mit64 MGI:MGI:90070 +62167 D14Mit65 MGI:MGI:90071 +62168 D14Mit66 MGI:MGI:90072 +62169 D14Mit67 MGI:MGI:90073 +62170 D14Mit71 MGI:MGI:90078 +62171 D14Mit74 MGI:MGI:90081 +62172 D14Mit79 MGI:MGI:90086 +62173 D14Mit83 MGI:MGI:90091 +62174 D14Mit91 MGI:MGI:90099 +62175 D14Mit94 MGI:MGI:90102 +62176 D14Mit95 MGI:MGI:90103 +62177 D14Mit97 MGI:MGI:90105 +62178 D15Mit11 MGI:MGI:90239 +62179 D15Mit14 MGI:MGI:90272 +62180 D15Mit20 MGI:MGI:90301 +62181 D15Mit22 MGI:MGI:90303 +62182 D15Mit25 MGI:MGI:90305 +62183 D15Mit33 MGI:MGI:90314 +62184 D15Mit37 MGI:MGI:90317 +62185 D15Mit40 MGI:MGI:90320 +62186 D15Mit41 MGI:MGI:90321 +62187 D15Mit44 MGI:MGI:90324 +62188 D15Mit46 MGI:MGI:90326 +62189 D15Mit51 MGI:MGI:90332 +62190 D15Mit57 MGI:MGI:90338 +62191 D15Mit58 MGI:MGI:90339 +62192 D15Mit61 MGI:MGI:90343 +62193 D15Mit62 MGI:MGI:90344 +62194 D15Mit64 MGI:MGI:90346 +62195 D15Mit65 MGI:MGI:90347 +62196 D15Mit66 MGI:MGI:90348 +62197 D15Mit67 MGI:MGI:90349 +62198 D15Mit71 MGI:MGI:90354 +62199 D15Mit72 MGI:MGI:90355 +62200 D15Mit73 MGI:MGI:90356 +62201 D15Mit75 MGI:MGI:90358 +62202 D15Mit79 MGI:MGI:90362 +62203 D15Mit81 MGI:MGI:90365 +62204 D15Mit88 MGI:MGI:90372 +62205 D15Mit96 MGI:MGI:90381 +62206 D16Mit19 MGI:MGI:90491 +62207 D16Mit26 MGI:MGI:90494 +62208 D16Mit34 MGI:MGI:90503 +62209 D16Mit37 MGI:MGI:90506 +62210 D16Mit38 MGI:MGI:90507 +62211 D16Mit39 MGI:MGI:90508 +62212 D16Mit41 MGI:MGI:90511 +62213 D16Mit43 MGI:MGI:90513 +62214 D16Mit49 MGI:MGI:90519 +62215 D16Mit50 MGI:MGI:90521 +62216 D16Mit58 MGI:MGI:90529 +62217 D16Mit59 MGI:MGI:90530 +62218 D16Mit60 MGI:MGI:90532 +62219 D16Mit64 MGI:MGI:90536 +62220 D16Mit78a MGI:MGI:90551 +62221 D16Mit84 MGI:MGI:90558 +62222 D16Mit87 MGI:MGI:90561 +62223 D16Mit89 MGI:MGI:90563 +62224 D16Mit93 MGI:MGI:90568 +62225 D16Mit95 MGI:MGI:90570 +62226 D17Mit29 MGI:MGI:90817 +62227 D17Mit33a MGI:MGI:90822 +62228 D17Mit34 MGI:MGI:90823 +62229 D17Mit38 MGI:MGI:90827 +62230 D17Mit39 MGI:MGI:90828 +62231 D17Mit41 MGI:MGI:90830 +62232 D17Mit42 MGI:MGI:90831 +62233 D17Mit44 MGI:MGI:90833 +62234 D17Mit51 MGI:MGI:90841 +62235 D17Mit52 MGI:MGI:90842 +62236 D17Mit56 MGI:MGI:90846 +62237 D17Mit60 MGI:MGI:90851 +62238 D17Mit66 MGI:MGI:90857 +62239 D17Mit67 MGI:MGI:90858 +62240 D17Mit70 MGI:MGI:90862 +62241 D17Mit71 MGI:MGI:90863 +62242 D17Mit73 MGI:MGI:90865 +62243 D17Mit74 MGI:MGI:90866 +62244 D17Mit76 MGI:MGI:90868 +62245 D17Mit89 MGI:MGI:90881 +62246 D17Mit92 MGI:MGI:90885 +62247 D17Mit95 MGI:MGI:90888 +62248 D18Mit24 MGI:MGI:91076 +62249 D18Mit25 MGI:MGI:91077 +62250 D18Mit33 MGI:MGI:91085 +62251 D18Mit34 MGI:MGI:91086 +62252 D18Mit35 MGI:MGI:91087 +62253 D18Mit36 MGI:MGI:91088 +62254 D18Mit37 MGI:MGI:91089 +62255 D18Mit46 MGI:MGI:91099 +62256 D18Mit47 MGI:MGI:91100 +62257 D18Mit49 MGI:MGI:91102 +62258 D18Mit53 MGI:MGI:91107 +62259 D18Mit57 MGI:MGI:91111 +62260 D18Mit69 MGI:MGI:91124 +62261 D18Mit88 MGI:MGI:91145 +62262 D18Mit90 MGI:MGI:91148 +62263 D18Mit91 MGI:MGI:91149 +62264 D18Mit93 MGI:MGI:91151 +62265 D18Mit94 MGI:MGI:91152 +62266 D19Mit11.1 MGI:MGI:91217 +62267 D19Mit16 MGI:MGI:91224 +62268 D19Mit17 MGI:MGI:91225 +62269 D19Mit19 MGI:MGI:91227 +62270 D19Mit23 MGI:MGI:91232 +62271 D19Mit24 MGI:MGI:91233 +62272 D19Mit25 MGI:MGI:91234 +62273 D19Mit27 MGI:MGI:91236 +62274 D19Mit28 MGI:MGI:91237 +62275 D19Mit30 MGI:MGI:91240 +62276 D19Mit35 MGI:MGI:91245 +62277 D19Mit36 MGI:MGI:91246 +62278 D19Mit38 MGI:MGI:91248 +62279 D19Mit39 MGI:MGI:91249 +62280 D19Mit41 MGI:MGI:91252 +62281 D19Mit45 MGI:MGI:91256 +62282 D19Mit46 MGI:MGI:91257 +62283 D19Mit47 MGI:MGI:91258 +62284 D19Mit49 MGI:MGI:91260 +62285 D19Mit53 MGI:MGI:91265 +62286 D19Mit54 MGI:MGI:91266 +62287 D19Mit55 MGI:MGI:91267 +62288 D19Mit57 MGI:MGI:91269 +62289 D19Mit58 MGI:MGI:91270 +62290 D19Mit60 MGI:MGI:91273 +62291 D19Mit63 MGI:MGI:91276 +62292 D19Mit65 MGI:MGI:91278 +62293 D19Mit66 MGI:MGI:91279 +62294 D19Mit71 MGI:MGI:91285 +62295 D1Mit1001 MGI:MGI:91286 +62296 D19Mit73 MGI:MGI:91287 +62297 D19Mit74 MGI:MGI:91288 +62298 D19Mit75 MGI:MGI:91289 +62299 D19Mit76 MGI:MGI:91290 +62300 D1Mit116 MGI:MGI:91486 +62301 D1Mit152 MGI:MGI:91526 +62302 D1Mit153 MGI:MGI:91527 +62303 D1Mit154 MGI:MGI:91528 +62304 D1Mit155 MGI:MGI:91529 +62305 D1Mit166 MGI:MGI:91541 +62306 D1Mit208 MGI:MGI:91587 +62307 D1Mit210 MGI:MGI:91590 +62308 D1Mit221 MGI:MGI:91602 +62309 D1Mit224 MGI:MGI:91605 +62310 D1Mit272 MGI:MGI:91658 +62311 D1Mit273 MGI:MGI:91659 +62312 D1Mit274 MGI:MGI:91660 +62313 D1Mit292 MGI:MGI:91680 +62314 D1Mit293 MGI:MGI:91681 +62315 D2Mit113 MGI:MGI:91970 +62316 D2Mit114 MGI:MGI:91971 +62317 D2Mit147 MGI:MGI:92007 +62318 D2Mit200 MGI:MGI:92065 +62319 D2Mit210 MGI:MGI:92076 +62320 D2Mit266 MGI:MGI:92136 +62321 D4Mit117 MGI:MGI:92739 +62322 D6Mit107 MGI:MGI:93532 +62323 D6Mit118 MGI:MGI:93544 +62324 D6Mit121 MGI:MGI:93548 +62325 D6Mit128 MGI:MGI:93555 +62326 D6Mit162 MGI:MGI:93593 +62327 D6Mit164 MGI:MGI:93595 +62328 D6Mit174 MGI:MGI:93606 +62329 D6Mit175 MGI:MGI:93607 +62330 D6Mit184 MGI:MGI:93616 +62331 DXMit146a MGI:MGI:100002 +62332 D6Mit256 MGI:MGI:100338 +62333 D6Mit255 MGI:MGI:100339 +62334 D6Mit247 MGI:MGI:100347 +62335 D19Mit99 MGI:MGI:100748 +62336 D19Mit98 MGI:MGI:100749 +62337 D19Mit96 MGI:MGI:100751 +62338 D19Mit91 MGI:MGI:100756 +62339 D19Mit86 MGI:MGI:100761 +62340 D19Mit85 MGI:MGI:100762 +62341 D19Mit84 MGI:MGI:100763 +62342 D19Mit83 MGI:MGI:100764 +62343 D19Mit82 MGI:MGI:100765 +62344 D19Mit81 MGI:MGI:100766 +62345 D1Mit408 MGI:MGI:101358 +62346 D1Mit407 MGI:MGI:101359 +62347 D1Mit406 MGI:MGI:101360 +62348 D1Mit405 MGI:MGI:101361 +62349 D1Mit404 MGI:MGI:101362 +62350 D1Mit403 MGI:MGI:101363 +62351 D1Mit362 MGI:MGI:101404 +62352 D1Mit360 MGI:MGI:101406 +62353 D1Mit315 MGI:MGI:101451 +62354 D1Mit458 MGI:MGI:101987 +62355 D1Mit461 MGI:MGI:101988 +62356 D1Mit459 MGI:MGI:101989 +62357 D1Mit462 MGI:MGI:101991 +62358 D1Mit463 MGI:MGI:101992 +62359 D6Mit334 MGI:MGI:102139 +62360 D10Mit279 MGI:MGI:105785 +62361 D10Mit281 MGI:MGI:105787 +62362 D13Mit300 MGI:MGI:105824 +62363 D13Mit302 MGI:MGI:105826 +62364 D14Mit251 MGI:MGI:105843 +62365 D14Mit252 MGI:MGI:105844 +62366 D14Mit253 MGI:MGI:105845 +62367 D1Mit543 MGI:MGI:107054 +62368 D4Mit362 MGI:MGI:703071 +62369 D10Mit153 MGI:MGI:88773 +62370 D10Mit168 MGI:MGI:88789 +62371 D11Mit133 MGI:MGI:89016 +62372 D11Mit162 MGI:MGI:89048 +62373 D11Mit97 MGI:MGI:89177 +62374 D12Mit135 MGI:MGI:89382 +62375 D12Mit151 MGI:MGI:89400 +62376 D12Mit168 MGI:MGI:89418 +62377 D13Mit114 MGI:MGI:89651 +62378 D13Mit134 MGI:MGI:89672 +62379 D13Mit158 MGI:MGI:89698 +62380 D13Mit173 MGI:MGI:89714 +62381 D14Mit110 MGI:MGI:89948 +62382 D14Mit112 MGI:MGI:89950 +62383 D14Mit126 MGI:MGI:89965 +62384 D14Mit137 MGI:MGI:89977 +62385 D14Mit138 MGI:MGI:89978 +62386 D14Mit171 MGI:MGI:90015 +62387 D16Mit100 MGI:MGI:90456 +62388 D16Mit108 MGI:MGI:90464 +62389 D16Mit109 MGI:MGI:90465 +62390 D16Mit28 MGI:MGI:90496 +62391 D16Mit29 MGI:MGI:90497 +62392 D16Mit51 MGI:MGI:90522 +62393 D16Mit98 MGI:MGI:90573 +62394 D17Mit113 MGI:MGI:90753 +62395 D17Mit16 MGI:MGI:90801 +62396 D17Mit62 MGI:MGI:90853 +62397 D17Mit63 MGI:MGI:90854 +62398 D18Mit116 MGI:MGI:91034 +62399 D18Mit117 MGI:MGI:91035 +62400 D18Mit169 MGI:MGI:100807 +62401 D18Mit146 MGI:MGI:100829 +62402 D17Mit196 MGI:MGI:100856 +62403 D4Mit1003 MGI:MGI:100889 +62404 D16Mit190 MGI:MGI:100891 +62405 D16Mit181 MGI:MGI:100900 +62406 D16Mit180 MGI:MGI:100901 +62407 D16Mit164 MGI:MGI:100917 +62408 D16Mit163 MGI:MGI:100918 +62409 D16Mit160 MGI:MGI:100921 +62410 D16Mit142 MGI:MGI:100939 +62411 D16Mit130 MGI:MGI:100950 +62412 D15Mit174 MGI:MGI:101001 +62413 D14Mit222 MGI:MGI:101021 +62414 D14Mit221 MGI:MGI:101022 +62415 D14Mit210 MGI:MGI:101033 +62416 D14Mit209 MGI:MGI:101034 +62417 D14Mit207 MGI:MGI:101036 +62418 D14Mit202 MGI:MGI:101041 +62419 D14Mit180 MGI:MGI:101063 +62420 D14Mit179 MGI:MGI:101064 +62421 D13Mit216 MGI:MGI:101119 +62422 D13Mit215 MGI:MGI:101120 +62423 D13Mit206 MGI:MGI:101129 +62424 D12Mit219 MGI:MGI:101151 +62425 D12Mit197 MGI:MGI:101173 +62426 D12Mit182 MGI:MGI:101188 +62427 D10Mit212 MGI:MGI:101308 +62428 D10Mit181 MGI:MGI:101339 +62429 D10Mit247 MGI:MGI:102243 +62430 D11Mit305 MGI:MGI:102270 +62431 D12Mit241 MGI:MGI:102306 +62432 D15Mit224 MGI:MGI:102367 +62433 D17Mit223 MGI:MGI:102405 +62434 D18Mit197 MGI:MGI:102427 +62435 D18Mit198 MGI:MGI:102428 +62436 D19Mit109 MGI:MGI:102447 +62437 D18Mit222 MGI:MGI:105401 +62438 D17Mit246 MGI:MGI:105419 +62439 D12Mit269 MGI:MGI:105435 +62440 D12Mit266 MGI:MGI:105438 +62441 D12Mit264 MGI:MGI:105440 +62442 D10Mit282 MGI:MGI:105788 +62443 D10Mit283 MGI:MGI:105789 +62444 D10Mit286 MGI:MGI:105792 +62445 D10Mit287a MGI:MGI:105793 +62446 D10Mit296 MGI:MGI:105802 +62447 D11Mit349 MGI:MGI:105810 +62448 D11Mit351 MGI:MGI:105812 +62449 D11Mit353 MGI:MGI:105814 +62450 D11Mit356 MGI:MGI:105817 +62451 D11Mit358 MGI:MGI:105819 +62452 D11Mit360 MGI:MGI:105821 +62453 D13Mit306 MGI:MGI:105830 +62454 D13Mit308 MGI:MGI:105831 +62455 D13Mit313 MGI:MGI:105836 +62456 D14Mit254 MGI:MGI:105846 +62457 D14Mit257 MGI:MGI:105849 +62458 D14Mit259 MGI:MGI:105851 +62459 D14Mit261 MGI:MGI:105853 +62460 D14Mit262 MGI:MGI:105854 +62461 D14Mit265 MGI:MGI:105857 +62462 D14Mit266 MGI:MGI:105858 +62463 D14Mit267 MGI:MGI:105859 +62464 D13Mit307 MGI:MGI:105860 +62465 D15Mit261 MGI:MGI:105871 +62466 D15Mit262 MGI:MGI:105872 +62467 D15Mit263 MGI:MGI:105873 +62468 D16Mit217 MGI:MGI:105883 +62469 D19Mit117 MGI:MGI:105888 +62470 D19Mit118 MGI:MGI:105889 +62471 D19Mit120 MGI:MGI:105891 +62472 D19Mit122 MGI:MGI:105893 +62473 D19Mit123 MGI:MGI:105894 +62474 D19Mit124 MGI:MGI:105895 +62475 D10Mit298 MGI:MGI:106928 +62476 D18Mit230 MGI:MGI:106973 +62477 D10Mit100 MGI:MGI:88716 +62478 D10Mit101 MGI:MGI:88717 +62479 D10Mit102 MGI:MGI:88718 +62480 D10Mit103 MGI:MGI:88719 +62481 D10Mit105 MGI:MGI:88721 +62482 D10Mit106 MGI:MGI:88722 +62483 D10Mit109 MGI:MGI:88725 +62484 D10Mit113 MGI:MGI:88730 +62485 D10Mit114 MGI:MGI:88731 +62486 D10Mit116 MGI:MGI:88733 +62487 D10Mit117 MGI:MGI:88734 +62488 D10Mit118 MGI:MGI:88735 +62489 D10Mit121 MGI:MGI:88739 +62490 D10Mit130 MGI:MGI:88749 +62491 D10Mit133 MGI:MGI:88752 +62492 D10Mit135 MGI:MGI:88754 +62493 D10Mit136 MGI:MGI:88755 +62494 D10Mit137 MGI:MGI:88756 +62495 D10Mit139 MGI:MGI:88758 +62496 D10Mit140 MGI:MGI:88760 +62497 D10Mit144 MGI:MGI:88764 +62498 D10Mit145 MGI:MGI:88765 +62499 D10Mit148 MGI:MGI:88768 +62500 D10Mit158 MGI:MGI:88778 +62501 D10Mit161 MGI:MGI:88782 +62502 D10Mit164 MGI:MGI:88785 +62503 D10Mit165 MGI:MGI:88786 +62504 D10Mit169 MGI:MGI:88790 +62505 D10Mit170 MGI:MGI:88792 +62506 D10Mit175 MGI:MGI:88797 +62507 D10Mit176 MGI:MGI:88798 +62508 D10Mit178 MGI:MGI:88800 +62509 D10Mit179 MGI:MGI:88801 +62510 D11Mit101 MGI:MGI:88981 +62511 D11Mit108 MGI:MGI:88988 +62512 D11Mit109 MGI:MGI:88989 +62513 D11Mit116 MGI:MGI:88997 +62514 D11Mit117 MGI:MGI:88998 +62515 D11Mit122 MGI:MGI:89004 +62516 D11Mit125 MGI:MGI:89007 +62517 D11Mit127 MGI:MGI:89009 +62518 D11Mit128 MGI:MGI:89010 +62519 D11Mit129 MGI:MGI:89011 +62520 D11Mit132 MGI:MGI:89015 +62521 D11Mit134 MGI:MGI:89017 +62522 D11Mit136 MGI:MGI:89019 +62523 D11Mit139 MGI:MGI:89022 +62524 D11Mit140 MGI:MGI:89024 +62525 D11Mit142 MGI:MGI:89026 +62526 D11Mit143 MGI:MGI:89027 +62527 D11Mit151 MGI:MGI:89036 +62528 D11Mit152 MGI:MGI:89037 +62529 D11Mit153 MGI:MGI:89038 +62530 D11Mit155a MGI:MGI:89040 +62531 D11Mit156 MGI:MGI:89041 +62532 D11Mit160 MGI:MGI:89046 +62533 D11Mit164 MGI:MGI:89050 +62534 D11Mit165 MGI:MGI:89051 +62535 D11Mit168 MGI:MGI:89054 +62536 D11Mit169 MGI:MGI:89055 +62537 D11Mit174 MGI:MGI:89060 +62538 D11Mit177 MGI:MGI:89063 +62539 D11Mit179 MGI:MGI:89065 +62540 D11Mit181 MGI:MGI:89067 +62541 D11Mit184 MGI:MGI:89070 +62542 D11Mit185 MGI:MGI:89071 +62543 D11Mit188 MGI:MGI:89074 +62544 D11Mit189 MGI:MGI:89075 +62545 D11Mit191 MGI:MGI:89078 +62546 D11Mit198 MGI:MGI:89085 +62547 D11Mit199 MGI:MGI:89086 +62548 D11Mit202 MGI:MGI:89091 +62549 D11Mit205 MGI:MGI:89094 +62550 D11Mit208 MGI:MGI:89097 +62551 D11Mit209 MGI:MGI:89098 +62552 D11Mit212 MGI:MGI:89102 +62553 D11Mit213 MGI:MGI:89103 +62554 D12Mit101 MGI:MGI:89345 +62555 D12Mit106 MGI:MGI:89350 +62556 D12Mit107 MGI:MGI:89351 +62557 D12Mit108 MGI:MGI:89352 +62558 D12Mit113 MGI:MGI:89358 +62559 D12Mit114 MGI:MGI:89359 +62560 D12Mit116 MGI:MGI:89361 +62561 D12Mit117 MGI:MGI:89362 +62562 D12Mit119 MGI:MGI:89364 +62563 D12Mit120 MGI:MGI:89366 +62564 D12Mit128 MGI:MGI:89374 +62565 D12Mit132 MGI:MGI:89379 +62566 D12Mit133 MGI:MGI:89380 +62567 D12Mit134 MGI:MGI:89381 +62568 D12Mit136 MGI:MGI:89383 +62569 D12Mit141 MGI:MGI:89389 +62570 D12Mit143 MGI:MGI:89391 +62571 D12Mit146 MGI:MGI:89394 +62572 D12Mit148 MGI:MGI:89396 +62573 D12Mit149 MGI:MGI:89397 +62574 D12Mit153 MGI:MGI:89402 +62575 D12Mit154 MGI:MGI:89403 +62576 D12Mit156 MGI:MGI:89405 +62577 D12Mit157 MGI:MGI:89406 +62578 D12Mit158 MGI:MGI:89407 +62579 D12Mit160 MGI:MGI:89410 +62580 D12Mit167 MGI:MGI:89417 +62581 D12Mit171 MGI:MGI:89422 +62582 D12Mit172 MGI:MGI:89423 +62583 D12Mit176 MGI:MGI:89427 +62584 D12Mit177a MGI:MGI:89428 +62585 D12Mit178 MGI:MGI:89429 +62586 D12Mit181 MGI:MGI:89433 +62587 D13Mit102 MGI:MGI:89638 +62588 D13Mit103 MGI:MGI:89639 +62589 D13Mit104 MGI:MGI:89640 +62590 D13Mit106 MGI:MGI:89642 +62591 D13Mit108 MGI:MGI:89644 +62592 D13Mit110 MGI:MGI:89647 +62593 D13Mit111 MGI:MGI:89648 +62594 D13Mit115 MGI:MGI:89652 +62595 D13Mit117 MGI:MGI:89654 +62596 D13Mit125 MGI:MGI:89662 +62597 D13Mit126 MGI:MGI:89663 +62598 D8Mit1003 MGI:MGI:89664 +62599 D13Mit128 MGI:MGI:89665 +62600 D13Mit129 MGI:MGI:89666 +62601 D13Mit130 MGI:MGI:89668 +62602 D13Mit136 MGI:MGI:89674 +62603 D13Mit137 MGI:MGI:89675 +62604 D13Mit139 MGI:MGI:89677 +62605 D13Mit140 MGI:MGI:89679 +62606 D13Mit141 MGI:MGI:89680 +62607 D13Mit144 MGI:MGI:89683 +62608 D13Mit148 MGI:MGI:89687 +62609 D13Mit149 MGI:MGI:89688 +62610 D13Mit157 MGI:MGI:89697 +62611 D13Mit159 MGI:MGI:89699 +62612 D13Mit160 MGI:MGI:89701 +62613 D13Mit161 MGI:MGI:89702 +62614 D13Mit163 MGI:MGI:89704 +62615 D13Mit166 MGI:MGI:89707 +62616 D13Mit169 MGI:MGI:89709 +62617 D13Mit170 MGI:MGI:89711 +62618 D13Mit181 MGI:MGI:89723 +62619 D13Mit185 MGI:MGI:89727 +62620 D13Mit196 MGI:MGI:89739 +62621 D13Mit199 MGI:MGI:89742 +62622 D13Mit202 MGI:MGI:89746 +62623 D13Mit203 MGI:MGI:89747 +62624 D13Mit204 MGI:MGI:89748 +62625 D14Mit101 MGI:MGI:89938 +62626 D14Mit104 MGI:MGI:89941 +62627 D14Mit105 MGI:MGI:89942 +62628 D14Mit106 MGI:MGI:89943 +62629 D14Mit113 MGI:MGI:89951 +62630 D14Mit116 MGI:MGI:89954 +62631 D14Mit118 MGI:MGI:89956 +62632 D14Mit121 MGI:MGI:89960 +62633 D14Mit123 MGI:MGI:89962 +62634 D14Mit124 MGI:MGI:89963 +62635 D14Mit130 MGI:MGI:89970 +62636 D14Mit131 MGI:MGI:89971 +62637 D14Mit132 MGI:MGI:89972 +62638 D14Mit136 MGI:MGI:89976 +62639 D14Mit141 MGI:MGI:89982 +62640 D14Mit142 MGI:MGI:89983 +62641 D14Mit144 MGI:MGI:89985 +62642 D14Mit153 MGI:MGI:89995 +62643 D14Mit154 MGI:MGI:89996 +62644 D14Mit155 MGI:MGI:89997 +62645 D14Mit156 MGI:MGI:89998 +62646 D14Mit157 MGI:MGI:89999 +62647 D14Mit159 MGI:MGI:90001 +62648 D14Mit160 MGI:MGI:90003 +62649 D14Mit163 MGI:MGI:90006 +62650 D14Mit164 MGI:MGI:90007 +62651 D14Mit166 MGI:MGI:90009 +62652 D9Mit1008 MGI:MGI:90012 +62653 D14Mit173 MGI:MGI:90017 +62654 D14Mit174 MGI:MGI:90018 +62655 D14Mit176 MGI:MGI:90020 +62656 D15Mit100 MGI:MGI:90229 +62657 D15Mit105 MGI:MGI:90234 +62658 D15Mit107 MGI:MGI:90236 +62659 D15Mit108 MGI:MGI:90237 +62660 D15Mit109 MGI:MGI:90238 +62661 D15Mit110 MGI:MGI:90240 +62662 D15Mit112 MGI:MGI:90242 +62663 D15Mit117 MGI:MGI:90247 +62664 D15Mit119 MGI:MGI:90249 +62665 D15Mit126 MGI:MGI:90257 +62666 D15Mit132 MGI:MGI:90264 +62667 D15Mit134 MGI:MGI:90266 +62668 D15Mit135 MGI:MGI:90267 +62669 D15Mit136 MGI:MGI:90268 +62670 D15Mit143 MGI:MGI:90276 +62671 D15Mit144 MGI:MGI:90277 +62672 D15Mit145 MGI:MGI:90278 +62673 D15Mit148 MGI:MGI:90281 +62674 D15Mit152 MGI:MGI:90286 +62675 D15Mit159 MGI:MGI:90293 +62676 D15Mit160 MGI:MGI:90295 +62677 D15Mit161 MGI:MGI:90296 +62678 D16Mit101 MGI:MGI:90457 +62679 D16Mit103 MGI:MGI:90459 +62680 D16Mit110 MGI:MGI:90467 +62681 D16Mit113 MGI:MGI:90470 +62682 D16Mit116 MGI:MGI:90473 +62683 D16Mit117 MGI:MGI:90474 +62684 D7Mit1002 MGI:MGI:90475 +62685 D16Mit120 MGI:MGI:90478 +62686 D16Mit122 MGI:MGI:90480 +62687 D16Mit124 MGI:MGI:90482 +62688 D16Mit127 MGI:MGI:90485 +62689 D16Mit128 MGI:MGI:90486 +62690 D17Mit101 MGI:MGI:90740 +62691 D17Mit108 MGI:MGI:90747 +62692 D17Mit110 MGI:MGI:90750 +62693 D17Mit115 MGI:MGI:90755 +62694 D17Mit118 MGI:MGI:90758 +62695 D17Mit119 MGI:MGI:90759 +62696 D17Mit122 MGI:MGI:90762 +62697 D17Mit123 MGI:MGI:90763 +62698 D17Mit129 MGI:MGI:90769 +62699 D17Mit130 MGI:MGI:90771 +62700 D17Mit132 MGI:MGI:90773 +62701 D17Mit136 MGI:MGI:90777 +62702 D17Mit138 MGI:MGI:90779 +62703 D17Mit139 MGI:MGI:90780 +62704 D17Mit140 MGI:MGI:90781 +62705 D17Mit141 MGI:MGI:90782 +62706 D17Mit145 MGI:MGI:90786 +62707 D17Mit150 MGI:MGI:90791 +62708 D17Mit151 MGI:MGI:90792 +62709 D17Mit153 MGI:MGI:90794 +62710 D17Mit155 MGI:MGI:90796 +62711 D17Mit158 MGI:MGI:90799 +62712 D17Mit160 MGI:MGI:90802 +62713 D18Mit103 MGI:MGI:91021 +62714 D18Mit104 MGI:MGI:91022 +62715 D18Mit111 MGI:MGI:91029 +62716 D18Mit115 MGI:MGI:91033 +62717 D18Mit121 MGI:MGI:91040 +62718 D18Mit122 MGI:MGI:91041 +62719 D18Mit124 MGI:MGI:91043 +62720 D18Mit130 MGI:MGI:91049 +62721 D18Mit138 MGI:MGI:91057 +62722 D18Mit141 MGI:MGI:91061 +62723 D18Mit143 MGI:MGI:91063 +62724 D18Mit145 MGI:MGI:91065 +62725 D19Mit108 MGI:MGI:100771 +62726 D19Mit106 MGI:MGI:100773 +62727 D19Mit105 MGI:MGI:100774 +62728 D19Mit104 MGI:MGI:100775 +62729 D19Mit103 MGI:MGI:100776 +62730 D19Mit101 MGI:MGI:100778 +62731 D18Mit193 MGI:MGI:100783 +62732 D18Mit189 MGI:MGI:100787 +62733 D18Mit187 MGI:MGI:100789 +62734 D18Mit185 MGI:MGI:100791 +62735 D18Mit184 MGI:MGI:100792 +62736 D18Mit181 MGI:MGI:100795 +62737 D18Mit179 MGI:MGI:100797 +62738 D18Mit174 MGI:MGI:100802 +62739 D18Mit172 MGI:MGI:100804 +62740 D18Mit171 MGI:MGI:100805 +62741 D18Mit159 MGI:MGI:100816 +62742 D18Mit152 MGI:MGI:100823 +62743 D17Mit218 MGI:MGI:100834 +62744 D17Mit216 MGI:MGI:100836 +62745 D17Mit214 MGI:MGI:100838 +62746 D17Mit209 MGI:MGI:100843 +62747 D17Mit208 MGI:MGI:100844 +62748 D17Mit207 MGI:MGI:100845 +62749 D17Mit206 MGI:MGI:100846 +62750 D17Mit203 MGI:MGI:100849 +62751 D17Mit200 MGI:MGI:100852 +62752 D17Mit199 MGI:MGI:100853 +62753 D17Mit198 MGI:MGI:100854 +62754 D17Mit190 MGI:MGI:100862 +62755 D17Mit189 MGI:MGI:100863 +62756 D17Mit188 MGI:MGI:100864 +62757 D17Mit187 MGI:MGI:100865 +62758 D17Mit185 MGI:MGI:100867 +62759 D17Mit184 MGI:MGI:100868 +62760 D17Mit181 MGI:MGI:100871 +62761 D17Mit180 MGI:MGI:100872 +62762 D17Mit175 MGI:MGI:100877 +62763 D17Mit174 MGI:MGI:100878 +62764 D16Mit188 MGI:MGI:100893 +62765 D16Mit185 MGI:MGI:100896 +62766 D16Mit184 MGI:MGI:100897 +62767 D16Mit179 MGI:MGI:100902 +62768 D16Mit178 MGI:MGI:100903 +62769 D16Mit176 MGI:MGI:100905 +62770 D16Mit165 MGI:MGI:100916 +62771 D16Mit159 MGI:MGI:100922 +62772 D16Mit156 MGI:MGI:100925 +62773 D16Mit155 MGI:MGI:100926 +62774 D16Mit151 MGI:MGI:100930 +62775 D16Mit145 MGI:MGI:100936 +62776 D16Mit143 MGI:MGI:100938 +62777 D16Mit140 MGI:MGI:100941 +62778 D16Mit138 MGI:MGI:100943 +62779 D16Mit137 MGI:MGI:100944 +62780 D16Mit135 MGI:MGI:100946 +62781 D16Mit134 MGI:MGI:100947 +62782 D16Mit133 MGI:MGI:100948 +62783 D15Mit221 MGI:MGI:100954 +62784 D15Mit218 MGI:MGI:100957 +62785 D15Mit216 MGI:MGI:100959 +62786 D15Mit212 MGI:MGI:100963 +62787 D15Mit208 MGI:MGI:100967 +62788 D15Mit207 MGI:MGI:100968 +62789 D15Mit202 MGI:MGI:100973 +62790 D15Mit198 MGI:MGI:100977 +62791 D15Mit196 MGI:MGI:100979 +62792 D15Mit188a MGI:MGI:100987 +62793 D15Mit184 MGI:MGI:100991 +62794 D15Mit173 MGI:MGI:101002 +62795 D15Mit171 MGI:MGI:101004 +62796 D15Mit167 MGI:MGI:101008 +62797 D14Mit228 MGI:MGI:101015 +62798 D14Mit225 MGI:MGI:101018 +62799 D14Mit224 MGI:MGI:101019 +62800 D14Mit219 MGI:MGI:101024 +62801 D14Mit217 MGI:MGI:101026 +62802 D14Mit215 MGI:MGI:101028 +62803 D14Mit214 MGI:MGI:101029 +62804 D14Mit212 MGI:MGI:101031 +62805 D14Mit204 MGI:MGI:101039 +62806 D14Mit203 MGI:MGI:101040 +62807 D14Mit200 MGI:MGI:101043 +62808 D14Mit199 MGI:MGI:101044 +62809 D14Mit197 MGI:MGI:101046 +62810 D14Mit193 MGI:MGI:101050 +62811 D14Mit192 MGI:MGI:101051 +62812 D14Mit189 MGI:MGI:101054 +62813 D13Mit270 MGI:MGI:101065 +62814 D13Mit269 MGI:MGI:101066 +62815 D13Mit267 MGI:MGI:101068 +62816 D13Mit266 MGI:MGI:101069 +62817 D13Mit265 MGI:MGI:101070 +62818 D13Mit262 MGI:MGI:101073 +62819 D13Mit261 MGI:MGI:101074 +62820 D13Mit260 MGI:MGI:101075 +62821 D13Mit250 MGI:MGI:101085 +62822 D13Mit249 MGI:MGI:101086 +62823 D13Mit247 MGI:MGI:101088 +62824 D13Mit244 MGI:MGI:101091 +62825 D13Mit243 MGI:MGI:101092 +62826 D13Mit234 MGI:MGI:101101 +62827 D13Mit233 MGI:MGI:101102 +62828 D13Mit232 MGI:MGI:101103 +62829 D13Mit231 MGI:MGI:101104 +62830 D13Mit230 MGI:MGI:101105 +62831 D13Mit226 MGI:MGI:101109 +62832 D13Mit213 MGI:MGI:101122 +62833 D12Mit239 MGI:MGI:101131 +62834 D12Mit238 MGI:MGI:101132 +62835 D12Mit236 MGI:MGI:101134 +62836 D12Mit235 MGI:MGI:101135 +62837 D12Mit231 MGI:MGI:101139 +62838 D12Mit230 MGI:MGI:101140 +62839 D12Mit228 MGI:MGI:101142 +62840 D12Mit227 MGI:MGI:101143 +62841 D12Mit226 MGI:MGI:101144 +62842 D12Mit222 MGI:MGI:101148 +62843 D12Mit221 MGI:MGI:101149 +62844 D12Mit214 MGI:MGI:101156 +62845 D12Mit213 MGI:MGI:101157 +62846 D12Mit211 MGI:MGI:101159 +62847 D12Mit210 MGI:MGI:101160 +62848 D12Mit207 MGI:MGI:101163 +62849 D12Mit205 MGI:MGI:101165 +62850 D12Mit199 MGI:MGI:101171 +62851 D12Mit196 MGI:MGI:101174 +62852 D12Mit194 MGI:MGI:101176 +62853 D12Mit192 MGI:MGI:101178 +62854 D12Mit191 MGI:MGI:101179 +62855 D12Mit190 MGI:MGI:101180 +62856 D12Mit189 MGI:MGI:101181 +62857 D12Mit186 MGI:MGI:101184 +62858 D12Mit185 MGI:MGI:101185 +62859 D11Mit301 MGI:MGI:101190 +62860 D11Mit297 MGI:MGI:101194 +62861 D11Mit295 MGI:MGI:101196 +62862 D11Mit294 MGI:MGI:101197 +62863 D11Mit291 MGI:MGI:101200 +62864 D11Mit290 MGI:MGI:101201 +62865 D11Mit289 MGI:MGI:101202 +62866 D11Mit288 MGI:MGI:101203 +62867 D11Mit287 MGI:MGI:101204 +62868 D11Mit285 MGI:MGI:101206 +62869 D11Mit284 MGI:MGI:101207 +62870 D11Mit279 MGI:MGI:101212 +62871 D11Mit276 MGI:MGI:101215 +62872 D11Mit271 MGI:MGI:101220 +62873 D11Mit269 MGI:MGI:101222 +62874 D11Mit264 MGI:MGI:101227 +62875 D11Mit263 MGI:MGI:101228 +62876 D11Mit258 MGI:MGI:101233 +62877 D11Mit254 MGI:MGI:101237 +62878 D11Mit245 MGI:MGI:101246 +62879 D11Mit236 MGI:MGI:101255 +62880 D11Mit235 MGI:MGI:101256 +62881 D11Mit234 MGI:MGI:101257 +62882 D11Mit233 MGI:MGI:101258 +62883 D11Mit231 MGI:MGI:101260 +62884 D11Mit230 MGI:MGI:101261 +62885 D11Mit226 MGI:MGI:101265 +62886 D11Mit225 MGI:MGI:101266 +62887 D11Mit223 MGI:MGI:101268 +62888 D11Mit221 MGI:MGI:101270 +62889 D11Mit219 MGI:MGI:101272 +62890 D11Mit218 MGI:MGI:101273 +62891 D11Mit216 MGI:MGI:101275 +62892 D11Mit215 MGI:MGI:101276 +62893 D10Mit242 MGI:MGI:101278 +62894 D10Mit238 MGI:MGI:101282 +62895 D10Mit235 MGI:MGI:101285 +62896 D10Mit234 MGI:MGI:101286 +62897 D10Mit231 MGI:MGI:101289 +62898 D10Mit230 MGI:MGI:101290 +62899 D10Mit223 MGI:MGI:101297 +62900 D10Mit222 MGI:MGI:101298 +62901 D10Mit221 MGI:MGI:101299 +62902 D10Mit220 MGI:MGI:101300 +62903 D10Mit216 MGI:MGI:101304 +62904 D10Mit214 MGI:MGI:101306 +62905 D10Mit213 MGI:MGI:101307 +62906 D10Mit209 MGI:MGI:101311 +62907 D10Mit207 MGI:MGI:101313 +62908 D10Mit204 MGI:MGI:101316 +62909 D10Mit203 MGI:MGI:101317 +62910 D10Mit202 MGI:MGI:101318 +62911 D10Mit200 MGI:MGI:101320 +62912 D10Mit199 MGI:MGI:101321 +62913 D10Mit197 MGI:MGI:101323 +62914 D10Mit192 MGI:MGI:101328 +62915 D10Mit187 MGI:MGI:101333 +62916 D10Mit185 MGI:MGI:101335 +62917 D10Mit183a MGI:MGI:101337 +62918 D10Mit249 MGI:MGI:102245 +62919 D10Mit250 MGI:MGI:102246 +62920 D10Mit251 MGI:MGI:102247 +62921 D10Mit253 MGI:MGI:102249 +62922 D10Mit255 MGI:MGI:102251 +62923 D10Mit259 MGI:MGI:102255 +62924 D10Mit260 MGI:MGI:102256 +62925 D10Mit262 MGI:MGI:102258 +62926 D10Mit263 MGI:MGI:102259 +62927 D10Mit264 MGI:MGI:102260 +62928 D10Mit265 MGI:MGI:102262 +62929 D10Mit267 MGI:MGI:102264 +62930 D10Mit271 MGI:MGI:102266 +62931 D10Mit269 MGI:MGI:102267 +62932 D11Mit306 MGI:MGI:102271 +62933 D11Mit307 MGI:MGI:102272 +62934 D11Mit308 MGI:MGI:102273 +62935 D11Mit309 MGI:MGI:102274 +62936 D11Mit314 MGI:MGI:102279 +62937 D11Mit315 MGI:MGI:102280 +62938 D11Mit339 MGI:MGI:102283 +62939 D11Mit318 MGI:MGI:102284 +62940 D11Mit319 MGI:MGI:102285 +62941 D11Mit320 MGI:MGI:102286 +62942 D11Mit321 MGI:MGI:102287 +62943 D11Mit322 MGI:MGI:102288 +62944 D11Mit323 MGI:MGI:102289 +62945 D11Mit325 MGI:MGI:102292 +62946 D11Mit327 MGI:MGI:102293 +62947 D11Mit328 MGI:MGI:102294 +62948 D11Mit329 MGI:MGI:102295 +62949 D11Mit330 MGI:MGI:102296 +62950 D11Mit331 MGI:MGI:102297 +62951 D11Mit332 MGI:MGI:102298 +62952 D11Mit336 MGI:MGI:102302 +62953 D12Mit254 MGI:MGI:102319 +62954 D12Mit256 MGI:MGI:102321 +62955 D12Mit257 MGI:MGI:102322 +62956 D12Mit258 MGI:MGI:102323 +62957 D12Mit259 MGI:MGI:102325 +62958 D12Mit261 MGI:MGI:102326 +62959 D12Mit262 MGI:MGI:102327 +62960 D12Mit263 MGI:MGI:102328 +62961 D13Mit278 MGI:MGI:102337 +62962 D13Mit291 MGI:MGI:102350 +62963 D13Mit292 MGI:MGI:102351 +62964 D13Mit293 MGI:MGI:102352 +62965 D14Mit234 MGI:MGI:102358 +62966 D14Mit236 MGI:MGI:102360 +62967 D14Mit238 MGI:MGI:102362 +62968 D14Mit239a MGI:MGI:102363 +62969 D15Mit226 MGI:MGI:102369 +62970 D15Mit231 MGI:MGI:102373 +62971 D15Mit237 MGI:MGI:102380 +62972 D15Mit239 MGI:MGI:102382 +62973 D15Mit241 MGI:MGI:102384 +62974 D15Mit242 MGI:MGI:102385 +62975 D15Mit243 MGI:MGI:102386 +62976 D15Mit244 MGI:MGI:102387 +62977 D16Mit193 MGI:MGI:102391 +62978 D16Mit194 MGI:MGI:102393 +62979 D16Mit201 MGI:MGI:102399 +62980 D16Mit202 MGI:MGI:102400 +62981 D17Mit226 MGI:MGI:102408 +62982 D17Mit231 MGI:MGI:102413 +62983 D17Mit234 MGI:MGI:102415 +62984 D17Mit235 MGI:MGI:102417 +62985 D17Mit242 MGI:MGI:102424 +62986 D18Mit206 MGI:MGI:102436 +62987 D18Mit208 MGI:MGI:102437 +62988 D18Mit209 MGI:MGI:102439 +62989 D18Mit210 MGI:MGI:102440 +62990 D19Mit111 MGI:MGI:102449 +62991 D17Mit258 MGI:MGI:105407 +62992 D17Mit257 MGI:MGI:105408 +62993 D12Mit280 MGI:MGI:105424 +62994 D12Mit279 MGI:MGI:105425 +62995 D12Mit275 MGI:MGI:105429 +62996 D12Mit274 MGI:MGI:105430 +62997 D10Mit299 MGI:MGI:106929 +62998 D10Mit301 MGI:MGI:106931 +62999 D10Mit304 MGI:MGI:106934 +63000 D12Mit283 MGI:MGI:106941 +63001 D12Mit284 MGI:MGI:106942 +63002 D12Mit285 MGI:MGI:106943 +63003 D12Mit288 MGI:MGI:106946 +63004 D14Mit268 MGI:MGI:106950 +63005 D15Mit266 MGI:MGI:106954 +63006 D15Mit270 MGI:MGI:106958 +63007 D15Mit272 MGI:MGI:106960 +63008 D18Mit238 MGI:MGI:106981 +63009 D19Mit128 MGI:MGI:106985 +63010 D19Mit129 MGI:MGI:106986 +63011 D19Mit130 MGI:MGI:106987 +63012 D19Mit131 MGI:MGI:106988 +63013 D19Mit132 MGI:MGI:106989 +63014 D19Mit136 MGI:MGI:106993 +63015 D19Mit137 MGI:MGI:106994 +63016 D1Mit273S MGI:MGI:107011 +63017 D17Mit274 MGI:MGI:705126 +63018 D11Mit119 MGI:MGI:89000 +63019 D16Mit106 MGI:MGI:90462 +63020 D17Mit100 MGI:MGI:90739 +63021 D17Mit104 MGI:MGI:90743 +63022 D17Mit105 MGI:MGI:90744 +63023 D17Mit192 MGI:MGI:100860 +63024 D17Mit168 MGI:MGI:100884 +63025 D11Mit260 MGI:MGI:101231 +63026 D16Mit195 MGI:MGI:102392 +63828 Fn3k MGI:MGI:1926834|Ensembl:ENSMUSG00000025175|Vega:OTTMUSG00000004677 +63830 Kcnq1ot1 MGI:MGI:1926855|Ensembl:ENSMUSG00000101609 +63831 DXMit20 MGI:MGI:95092 +63832 D11Mit54 MGI:MGI:89134 +63833 D15Mit15 MGI:MGI:90283 +63856 Taf8 MGI:MGI:1926879|Ensembl:ENSMUSG00000023980 +63857 Bco1 MGI:MGI:1926923|Ensembl:ENSMUSG00000031845|Vega:OTTMUSG00000023047 +63859 Impg1 MGI:MGI:1926876|Ensembl:ENSMUSG00000032343|Vega:OTTMUSG00000044863 +63872 Zfp296 MGI:MGI:1926956|Ensembl:ENSMUSG00000011267|Vega:OTTMUSG00000024036 +63873 Trpv4 MGI:MGI:1926945|Ensembl:ENSMUSG00000014158|Vega:OTTMUSG00000014501 +63913 Fam129a MGI:MGI:2137237|Ensembl:ENSMUSG00000026483|Vega:OTTMUSG00000021503 +63953 Dusp10 MGI:MGI:1927070|Ensembl:ENSMUSG00000039384|Vega:OTTMUSG00000033984 +63954 Rbp7 MGI:MGI:1890409|Ensembl:ENSMUSG00000028996|Vega:OTTMUSG00000010266 +63955 Cables1 MGI:MGI:1927065|Ensembl:ENSMUSG00000040957 +63958 Ube4b MGI:MGI:1927086|Ensembl:ENSMUSG00000028960|Vega:OTTMUSG00000010171 +63959 Slc29a1 MGI:MGI:1927073|Ensembl:ENSMUSG00000023942|Vega:OTTMUSG00000036637 +63985 Gmfb MGI:MGI:1927133|Ensembl:ENSMUSG00000062014|Vega:OTTMUSG00000023884 +63986 Gmfg MGI:MGI:1927135|Ensembl:ENSMUSG00000060791|Vega:OTTMUSG00000022974 +63993 Slc5a7 MGI:MGI:1927126|Ensembl:ENSMUSG00000023945 +64008 Aqp9 MGI:MGI:1891066|Ensembl:ENSMUSG00000032204|Vega:OTTMUSG00000023895 +64009 Syne1 MGI:MGI:1927152|Ensembl:ENSMUSG00000096054|Vega:OTTMUSG00000063506 +64010 Sav1 MGI:MGI:1927144|Ensembl:ENSMUSG00000021067 +64011 Nrgn MGI:MGI:1927184|Ensembl:ENSMUSG00000053310|Vega:OTTMUSG00000043307 +64050 Yeats4 MGI:MGI:1927224|Ensembl:ENSMUSG00000020171 +64051 Sv2a MGI:MGI:1927139|Ensembl:ENSMUSG00000038486|Vega:OTTMUSG00000021899 +64058 Perp MGI:MGI:1929938|Ensembl:ENSMUSG00000019851|Vega:OTTMUSG00000063685 +64059 Oxct2a MGI:MGI:1891061|Ensembl:ENSMUSG00000076436|Vega:OTTMUSG00000008979 +64074 Smoc2 MGI:MGI:1929881|Ensembl:ENSMUSG00000023886 +64075 Smoc1 MGI:MGI:1929878|Ensembl:ENSMUSG00000021136|Vega:OTTMUSG00000033861 +64082 Popdc2 MGI:MGI:1930150|Ensembl:ENSMUSG00000022803|Vega:OTTMUSG00000024842 +64085 Clstn2 MGI:MGI:1929897|Ensembl:ENSMUSG00000032452|Vega:OTTMUSG00000032788 +64095 Gpr35 MGI:MGI:1929509|Ensembl:ENSMUSG00000026271|Vega:OTTMUSG00000048633 +64099 Parvg MGI:MGI:2158329|Ensembl:ENSMUSG00000022439|Vega:OTTMUSG00000026123 +64103 Tnmd MGI:MGI:1929885|Ensembl:ENSMUSG00000031250|Vega:OTTMUSG00000018674 +64113 Moap1 MGI:MGI:1915555|Ensembl:ENSMUSG00000096458|Vega:OTTMUSG00000037134 +64136 Sdf2l1 MGI:MGI:2149842|Ensembl:ENSMUSG00000022769|Vega:OTTMUSG00000024838 +64138 Ctsz MGI:MGI:1891190|Ensembl:ENSMUSG00000016256|Vega:OTTMUSG00000016461 +64139 Ctsm MGI:MGI:1927229|Ensembl:ENSMUSG00000074871 +64143 Ralb MGI:MGI:1927244|Ensembl:ENSMUSG00000004451|Vega:OTTMUSG00000021776 +64144 Mllt1 MGI:MGI:1927238|Ensembl:ENSMUSG00000024212 +64176 Sv2b MGI:MGI:1927338|Ensembl:ENSMUSG00000053025|Vega:OTTMUSG00000058388 +64177 Trpv6 MGI:MGI:1927259|Ensembl:ENSMUSG00000029868|Vega:OTTMUSG00000051429 +64209 Herpud1 MGI:MGI:1927406|Ensembl:ENSMUSG00000031770|Vega:OTTMUSG00000027364 +64213 St7 MGI:MGI:1927450|Ensembl:ENSMUSG00000029534|Vega:OTTMUSG00000015033 +64214 Rgs18 MGI:MGI:1927498|Ensembl:ENSMUSG00000026357|Vega:OTTMUSG00000026870 +64242 Ngb MGI:MGI:2151886|Ensembl:ENSMUSG00000021032|Vega:OTTMUSG00000020165 +64243 Snord116 Ensembl:ENSMUSG00000096019 +64244 Snord116l1 MGI:MGI:1927532|Ensembl:ENSMUSG00000096475 +64245 Snord116l2 MGI:MGI:1927533|Ensembl:ENSMUSG00000096759 +64246 Snord116l3 MGI:MGI:1927534 +64247 Snord116l4 MGI:MGI:1927535 +64248 Snord116l5 MGI:MGI:1927536 +64249 Snord116l6 MGI:MGI:1927537 +64250 Snord116l7 MGI:MGI:1927538 +64251 Snord116l8 MGI:MGI:1927539 +64252 Snord116l9 MGI:MGI:1927540 +64290 Foxb1 MGI:MGI:1927549|Ensembl:ENSMUSG00000059246|Vega:OTTMUSG00000062761 +64291 Osbpl1a MGI:MGI:1927551|Ensembl:ENSMUSG00000044252|Vega:OTTMUSG00000030147 +64292 Ptges MGI:MGI:1927593|Ensembl:ENSMUSG00000050737|Vega:OTTMUSG00000011878 +64293 Stk32b MGI:MGI:1927552|Ensembl:ENSMUSG00000029123|Vega:OTTMUSG00000056098 +64294 Itm2c MGI:MGI:1927594|Ensembl:ENSMUSG00000026223|Vega:OTTMUSG00000029979 +64295 Tmub1 MGI:MGI:1923764|Ensembl:ENSMUSG00000028958|Vega:OTTMUSG00000024198 +64296 Abhd8 MGI:MGI:1918946|Ensembl:ENSMUSG00000007950|Vega:OTTMUSG00000062155 +64297 Gprc5b MGI:MGI:1927596|Ensembl:ENSMUSG00000008734|Vega:OTTMUSG00000059047 +64335 Svs3a MGI:MGI:1927635|Ensembl:ENSMUSG00000017003|Vega:OTTMUSG00000001084 +64337 Gng13 MGI:MGI:1925616|Ensembl:ENSMUSG00000025739|Vega:OTTMUSG00000035881 +64339 Fndc4 MGI:MGI:1917195|Ensembl:ENSMUSG00000038552|Vega:OTTMUSG00000055349 +64340 Dhx38 MGI:MGI:1927617|Ensembl:ENSMUSG00000037993|Vega:OTTMUSG00000061917 +64378 Gpr88 MGI:MGI:1927653|Ensembl:ENSMUSG00000068696|Vega:OTTMUSG00000054451 +64379 Irx6 MGI:MGI:1927642|Ensembl:ENSMUSG00000031738|Vega:OTTMUSG00000035969 +64380 Ms4a4c MGI:MGI:1927656|Ensembl:ENSMUSG00000024675|Vega:OTTMUSG00000028265 +64381 Ms4a8a MGI:MGI:1927657|Ensembl:ENSMUSG00000024730|Vega:OTTMUSG00000047015 +64383 Sirt2 MGI:MGI:1927664|Ensembl:ENSMUSG00000015149|Vega:OTTMUSG00000017294 +64384 Sirt3 MGI:MGI:1927665|Ensembl:ENSMUSG00000025486|Vega:OTTMUSG00000023441 +64385 Cyp4f14 MGI:MGI:1927669|Ensembl:ENSMUSG00000024292 +64406 Sp5 MGI:MGI:1927715|Ensembl:ENSMUSG00000075304|Vega:OTTMUSG00000033266 +64424 Polr1e MGI:MGI:1929022|Ensembl:ENSMUSG00000028318|Vega:OTTMUSG00000007388 +64435 Fcamr MGI:MGI:1927803|Ensembl:ENSMUSG00000026415|Vega:OTTMUSG00000026760 +64436 Inpp5e MGI:MGI:1927753|Ensembl:ENSMUSG00000026925|Vega:OTTMUSG00000012777 +64449 Zfp279 MGI:MGI:1927853 +64450 Gpr85 MGI:MGI:1927851|Ensembl:ENSMUSG00000048216|Vega:OTTMUSG00000022773 +64451 Dip2a MGI:MGI:2385920|Ensembl:ENSMUSG00000020231|Vega:OTTMUSG00000032492 +64452 Slc5a4a MGI:MGI:1927848|Ensembl:ENSMUSG00000020229 +64453 Zfp280b MGI:MGI:1927865|Ensembl:ENSMUSG00000049764 +64454 Slc5a4b MGI:MGI:1890478|Ensembl:ENSMUSG00000020226|Vega:OTTMUSG00000031869 +64540 Tspan4 MGI:MGI:1928097|Ensembl:ENSMUSG00000025511|Vega:OTTMUSG00000028948 +64580 Ndst4 MGI:MGI:1932545|Ensembl:ENSMUSG00000027971|Vega:OTTMUSG00000025050 +64602 Ireb2 MGI:MGI:1928268|Ensembl:ENSMUSG00000032293|Vega:OTTMUSG00000063245 +64652 Nisch MGI:MGI:1928323|Ensembl:ENSMUSG00000021910|Vega:OTTMUSG00000035875 +64654 Fgf23 MGI:MGI:1891427|Ensembl:ENSMUSG00000000182|Vega:OTTMUSG00000056344 +64655 Mrps22 MGI:MGI:1928137|Ensembl:ENSMUSG00000032459|Vega:OTTMUSG00000047584 +64656 Mrps23 MGI:MGI:1928138|Ensembl:ENSMUSG00000023723|Vega:OTTMUSG00000001484 +64657 Mrps10 MGI:MGI:1928139|Ensembl:ENSMUSG00000034729|Vega:OTTMUSG00000031581 +64658 Mrps25 MGI:MGI:1928140|Ensembl:ENSMUSG00000014551|Vega:OTTMUSG00000023997 +64659 Mrps14 MGI:MGI:1928141|Ensembl:ENSMUSG00000058267|Vega:OTTMUSG00000021950 +64660 Mrps24 MGI:MGI:1928142|Ensembl:ENSMUSG00000020477|Vega:OTTMUSG00000005096 +64661 Krtdap MGI:MGI:1928282|Ensembl:ENSMUSG00000074199|Vega:OTTMUSG00000049766 +64685 Nmi MGI:MGI:1928368|Ensembl:ENSMUSG00000026946|Vega:OTTMUSG00000012435 +64697 Keg1 MGI:MGI:1928492|Ensembl:ENSMUSG00000024694|Vega:OTTMUSG00000028295 +64704 Htra2 MGI:MGI:1928676|Ensembl:ENSMUSG00000068329|Vega:OTTMUSG00000022486 +64705 Dpys MGI:MGI:1928679|Ensembl:ENSMUSG00000022304|Vega:OTTMUSG00000033243 +64706 Scube1 MGI:MGI:1890616|Ensembl:ENSMUSG00000016763|Vega:OTTMUSG00000021075 +64707 Suv39h2 MGI:MGI:1890396|Ensembl:ENSMUSG00000026646|Vega:OTTMUSG00000010791 +64817 Svep1 MGI:MGI:1928849|Ensembl:ENSMUSG00000028369|Vega:OTTMUSG00000007439 +64818 Krt81 MGI:MGI:1928858|Ensembl:ENSMUSG00000067615 +64821 Cigs1 MGI:MGI:1928882 +64833 Acot10 MGI:MGI:1928940|Ensembl:ENSMUSG00000047565 +64898 Lpin2 MGI:MGI:1891341|Ensembl:ENSMUSG00000024052|Vega:OTTMUSG00000024753 +64899 Lpin3 MGI:MGI:1891342|Ensembl:ENSMUSG00000027412|Vega:OTTMUSG00000001176 +64903 Rpl30-ps5 MGI:MGI:1929159 +64918 Bhmt2 MGI:MGI:1891379|Ensembl:ENSMUSG00000042118|Vega:OTTMUSG00000024451 +64929 Scel MGI:MGI:1891228|Ensembl:ENSMUSG00000022123 +64930 Tsc1 MGI:MGI:1929183|Ensembl:ENSMUSG00000026812|Vega:OTTMUSG00000011747 +64931 Izumo1r MGI:MGI:1929185|Ensembl:ENSMUSG00000031933|Vega:OTTMUSG00000027394 +64933 Ap3m2 MGI:MGI:1929214|Ensembl:ENSMUSG00000031539|Vega:OTTMUSG00000060896 +64934 Pes1 MGI:MGI:1890613|Ensembl:ENSMUSG00000020430|Vega:OTTMUSG00000005041 +64938 Cigs2 MGI:MGI:1929205 +64945 Cldn12 MGI:MGI:1929288|Ensembl:ENSMUSG00000046798|Vega:OTTMUSG00000025945 +65019 Rpl23 MGI:MGI:1929455|Ensembl:ENSMUSG00000071415|Vega:OTTMUSG00000002776 +65020 Zfp110 MGI:MGI:1890378|Ensembl:ENSMUSG00000058638|Vega:OTTMUSG00000022354 +65079 Rtn4r MGI:MGI:2136886|Ensembl:ENSMUSG00000043811|Vega:OTTMUSG00000036604 +65086 Lpar3 MGI:MGI:1929469|Ensembl:ENSMUSG00000036832|Vega:OTTMUSG00000055329 +65098 Zfand6 MGI:MGI:1929510|Ensembl:ENSMUSG00000030629|Vega:OTTMUSG00000059542 +65099 Irak1bp1 MGI:MGI:1929475|Ensembl:ENSMUSG00000032251|Vega:OTTMUSG00000044898 +65100 Zic5 MGI:MGI:1929518|Ensembl:ENSMUSG00000041703|Vega:OTTMUSG00000020976 +65102 Nif3l1 MGI:MGI:1929485|Ensembl:ENSMUSG00000026036|Vega:OTTMUSG00000021967 +65103 Arl6ip6 MGI:MGI:1929507|Ensembl:ENSMUSG00000026960|Vega:OTTMUSG00000012443 +65105 Arl6ip4 MGI:MGI:1929500|Ensembl:ENSMUSG00000029404|Vega:OTTMUSG00000028866 +65106 Arl6ip5 MGI:MGI:1929501|Ensembl:ENSMUSG00000035199|Vega:OTTMUSG00000023411 +65107 Lrp10 MGI:MGI:1929480|Ensembl:ENSMUSG00000022175 +65111 Dap3 MGI:MGI:1929538|Ensembl:ENSMUSG00000068921|Vega:OTTMUSG00000031317 +65112 Pmepa1 MGI:MGI:1929600|Ensembl:ENSMUSG00000038400|Vega:OTTMUSG00000016685 +65113 Ndfip1 MGI:MGI:1929601|Ensembl:ENSMUSG00000024425 +65114 Vps35 MGI:MGI:1890467|Ensembl:ENSMUSG00000031696|Vega:OTTMUSG00000061416 +65115 Bean1 MGI:MGI:1929597|Ensembl:ENSMUSG00000031872|Vega:OTTMUSG00000061862 +65116 Prrg2 MGI:MGI:1929596|Ensembl:ENSMUSG00000007837|Vega:OTTMUSG00000023492 +65221 Slc15a3 MGI:MGI:1929691|Ensembl:ENSMUSG00000024737|Vega:OTTMUSG00000028260 +65246 Xpo7 MGI:MGI:1929705|Ensembl:ENSMUSG00000022100 +65247 Asb1 MGI:MGI:1929735|Ensembl:ENSMUSG00000026311|Vega:OTTMUSG00000048498 +65254 Dpysl5 MGI:MGI:1929772|Ensembl:ENSMUSG00000029168|Vega:OTTMUSG00000022301 +65255 Asb4 MGI:MGI:1929751|Ensembl:ENSMUSG00000042607|Vega:OTTMUSG00000026852 +65256 Asb2 MGI:MGI:1929743|Ensembl:ENSMUSG00000021200|Vega:OTTMUSG00000023083 +65257 Asb3 MGI:MGI:1929749|Ensembl:ENSMUSG00000020305|Vega:OTTMUSG00000005359 +65945 Clstn1 MGI:MGI:1929895|Ensembl:ENSMUSG00000039953|Vega:OTTMUSG00000010265 +65946 AA273854 MGI:MGI:1929894 +65948 DXCch1 MGI:MGI:1891437 +65949 DXCch2 MGI:MGI:1891438 +65951 DXCch4 MGI:MGI:1929887 +65952 DXCch5 MGI:MGI:1929889 +65956 Ccl21c MGI:MGI:1891386|Ensembl:ENSMUSG00000096873 +65957 Ccl19-ps1 MGI:MGI:1891387 +65958 Ccl19-ps2 MGI:MGI:1891390 +65959 Ccl19-ps3 MGI:MGI:1891391 +65960 Twsg1 MGI:MGI:2137520|Ensembl:ENSMUSG00000024098 +65961 Utp3 MGI:MGI:1919230|Ensembl:ENSMUSG00000070697|Vega:OTTMUSG00000055390 +65962 Slc9a3r2 MGI:MGI:1890662|Ensembl:ENSMUSG00000002504 +65963 Tmem176b MGI:MGI:1916348|Ensembl:ENSMUSG00000029810|Vega:OTTMUSG00000057390 +65964 Map3k20 MGI:MGI:2443258|Ensembl:ENSMUSG00000004085|Vega:OTTMUSG00000013165 +65967 Eefsec MGI:MGI:2137092|Ensembl:ENSMUSG00000033216|Vega:OTTMUSG00000057348 +65969 Cubn MGI:MGI:1931256|Ensembl:ENSMUSG00000026726|Vega:OTTMUSG00000011227 +65970 Lima1 MGI:MGI:1920992|Ensembl:ENSMUSG00000023022|Vega:OTTMUSG00000036466 +65971 Tbata MGI:MGI:1923820|Ensembl:ENSMUSG00000020096|Vega:OTTMUSG00000031951 +65972 Ifi30 MGI:MGI:2137648 +65973 Asph MGI:MGI:1914186|Ensembl:ENSMUSG00000028207|Vega:OTTMUSG00000004455 +66011 Ranbp17 MGI:MGI:1929706|Ensembl:ENSMUSG00000040594|Vega:OTTMUSG00000005398 +66039 Tmem254a MGI:MGI:1196450|Ensembl:ENSMUSG00000072676|Vega:OTTMUSG00000044551 +66042 Sostdc1 MGI:MGI:1913292|Ensembl:ENSMUSG00000036169 +66043 Atp5d MGI:MGI:1913293|Ensembl:ENSMUSG00000003072|Vega:OTTMUSG00000000005 +66044 Dtd1 MGI:MGI:1913294|Ensembl:ENSMUSG00000027430|Vega:OTTMUSG00000003939 +66046 Ndufb5 MGI:MGI:1913296|Ensembl:ENSMUSG00000027673|Vega:OTTMUSG00000028013 +66047 Mrpl54 MGI:MGI:1913297|Ensembl:ENSMUSG00000034932|Vega:OTTMUSG00000030358 +66048 Emc6 MGI:MGI:1913298|Ensembl:ENSMUSG00000047260|Vega:OTTMUSG00000006119 +66049 Rogdi MGI:MGI:1913299|Ensembl:ENSMUSG00000022540|Vega:OTTMUSG00000055592 +66050 0610009B22Rik MGI:MGI:1913300|Ensembl:ENSMUSG00000007777|Vega:OTTMUSG00000005608 +66052 Sdhc MGI:MGI:1913302|Ensembl:ENSMUSG00000058076|Vega:OTTMUSG00000021661 +66053 Ppil2 MGI:MGI:2447857|Ensembl:ENSMUSG00000022771|Vega:OTTMUSG00000024117 +66054 Cndp2 MGI:MGI:1913304|Ensembl:ENSMUSG00000024644 +66055 Sf3b6 MGI:MGI:1913305|Ensembl:ENSMUSG00000037361 +66056 Zfp524 MGI:MGI:1916740|Ensembl:ENSMUSG00000051184|Vega:OTTMUSG00000058586 +66058 Tmem176a MGI:MGI:1913308|Ensembl:ENSMUSG00000023367|Vega:OTTMUSG00000057391 +66059 Krtcap2 MGI:MGI:1913309|Ensembl:ENSMUSG00000042747|Vega:OTTMUSG00000022000 +66060 Cystm1 MGI:MGI:1913310|Ensembl:ENSMUSG00000046727|Vega:OTTMUSG00000032601 +66061 Tctex1d2 MGI:MGI:1913311|Ensembl:ENSMUSG00000014075|Vega:OTTMUSG00000025781 +66065 Hsd17b14 MGI:MGI:1913315|Ensembl:ENSMUSG00000030825|Vega:OTTMUSG00000021062 +66066 Gng11 MGI:MGI:1913316|Ensembl:ENSMUSG00000032766|Vega:OTTMUSG00000035919 +66067 Gtpbp8 MGI:MGI:1913317|Ensembl:ENSMUSG00000022668|Vega:OTTMUSG00000028474 +66069 Snupn MGI:MGI:1913319|Ensembl:ENSMUSG00000055334|Vega:OTTMUSG00000031810 +66070 Cwc15 MGI:MGI:1913320|Ensembl:ENSMUSG00000004096|Vega:OTTMUSG00000034185 +66071 Ethe1 MGI:MGI:1913321|Ensembl:ENSMUSG00000064254|Vega:OTTMUSG00000031266 +66072 Sdhaf2 MGI:MGI:1913322|Ensembl:ENSMUSG00000024668 +66073 Txndc12 MGI:MGI:1913323|Ensembl:ENSMUSG00000028567|Vega:OTTMUSG00000008252 +66074 Tmem167 MGI:MGI:1913324|Ensembl:ENSMUSG00000012422|Vega:OTTMUSG00000034339 +66075 Chchd3 MGI:MGI:1913325|Ensembl:ENSMUSG00000053768|Vega:OTTMUSG00000014758 +66077 Aurkaip1 MGI:MGI:1913327|Ensembl:ENSMUSG00000065990|Vega:OTTMUSG00000010895 +66078 Tsen34 MGI:MGI:1913328|Ensembl:ENSMUSG00000035585|Vega:OTTMUSG00000023033 +66079 Tmem42 MGI:MGI:1277176|Ensembl:ENSMUSG00000066233|Vega:OTTMUSG00000062838 +66082 Abhd6 MGI:MGI:1913332|Ensembl:ENSMUSG00000025277 +66083 Setd6 MGI:MGI:1913333|Ensembl:ENSMUSG00000031671|Vega:OTTMUSG00000017453 +66084 Rmnd1 MGI:MGI:1913334|Ensembl:ENSMUSG00000019763|Vega:OTTMUSG00000030953 +66085 Eif3f MGI:MGI:1913335|Ensembl:ENSMUSG00000031029|Vega:OTTMUSG00000026004 +66086 Fopnl MGI:MGI:1913336|Ensembl:ENSMUSG00000022677|Vega:OTTMUSG00000027055 +66087 Emc3 MGI:MGI:1913337|Ensembl:ENSMUSG00000030286|Vega:OTTMUSG00000023489 +66089 Rmnd5b MGI:MGI:1913339|Ensembl:ENSMUSG00000001054|Vega:OTTMUSG00000005605 +66090 Ypel3 MGI:MGI:1913340|Ensembl:ENSMUSG00000042675|Vega:OTTMUSG00000022962 +66091 Ndufa3 MGI:MGI:1913341|Ensembl:ENSMUSG00000035674|Vega:OTTMUSG00000023398 +66092 Ghitm MGI:MGI:1913342|Ensembl:ENSMUSG00000041028 +66094 Lsm7 MGI:MGI:1913344|Ensembl:ENSMUSG00000035215 +66096 Lamtor4 MGI:MGI:1913346|Ensembl:ENSMUSG00000050552|Vega:OTTMUSG00000022731 +66098 Chchd6 MGI:MGI:1913348|Ensembl:ENSMUSG00000030086|Vega:OTTMUSG00000057681 +66101 Ppih MGI:MGI:106499|Ensembl:ENSMUSG00000060288|Vega:OTTMUSG00000009258 +66102 Cxcl16 MGI:MGI:1932682|Ensembl:ENSMUSG00000018920|Vega:OTTMUSG00000006042 +66104 Tceal6 MGI:MGI:1923939|Ensembl:ENSMUSG00000031409|Vega:OTTMUSG00000018755 +66105 Ube2d3 MGI:MGI:1913355|Ensembl:ENSMUSG00000078578|Vega:OTTMUSG00000054825 +66106 Smpx MGI:MGI:1913356|Ensembl:ENSMUSG00000041476|Vega:OTTMUSG00000019394 +66107 Wfdc21 MGI:MGI:1913357|Ensembl:ENSMUSG00000051748|Vega:OTTMUSG00000000976 +66108 Ndufa9 MGI:MGI:1913358|Ensembl:ENSMUSG00000000399|Vega:OTTMUSG00000056335 +66109 Tspan13 MGI:MGI:1913359|Ensembl:ENSMUSG00000020577|Vega:OTTMUSG00000027581 +66111 Tmed3 MGI:MGI:1913361|Ensembl:ENSMUSG00000032353|Vega:OTTMUSG00000046286 +66112 Marc1 MGI:MGI:1913362|Ensembl:ENSMUSG00000026621|Vega:OTTMUSG00000045414 +66113 Apoa5 MGI:MGI:1913363|Ensembl:ENSMUSG00000032079|Vega:OTTMUSG00000028704 +66114 Dnajc30 MGI:MGI:1913364|Ensembl:ENSMUSG00000061118|Vega:OTTMUSG00000026014 +66116 Nat8f1 MGI:MGI:1913366|Ensembl:ENSMUSG00000057103|Vega:OTTMUSG00000034538 +66117 Fmc1 MGI:MGI:1913367|Ensembl:ENSMUSG00000019689|Vega:OTTMUSG00000024224 +66118 Sarnp MGI:MGI:1913368|Ensembl:ENSMUSG00000078427 +66119 Tomm6 MGI:MGI:1913369|Ensembl:ENSMUSG00000033475|Vega:OTTMUSG00000018357 +66120 Fkbp11 MGI:MGI:1913370|Ensembl:ENSMUSG00000003355 +66121 Chchd1 MGI:MGI:1913371|Ensembl:ENSMUSG00000063787 +66123 1110006O24Rik MGI:MGI:1913373|Ensembl:ENSMUSG00000107121 +66124 Josd2 MGI:MGI:1913374|Ensembl:ENSMUSG00000038695|Vega:OTTMUSG00000029006 +66125 Sf3b5 MGI:MGI:1913375|Ensembl:ENSMUSG00000078348|Vega:OTTMUSG00000042396 +66126 Elof1 MGI:MGI:1913376|Ensembl:ENSMUSG00000013822|Vega:OTTMUSG00000062333 +66127 1110014L15Rik MGI:MGI:1913377 +66128 Mrps36 MGI:MGI:1913378|Ensembl:ENSMUSG00000061474|Vega:OTTMUSG00000022878 +66129 Aaed1 MGI:MGI:1913379|Ensembl:ENSMUSG00000021482 +66131 Tipin MGI:MGI:1921571|Ensembl:ENSMUSG00000032397|Vega:OTTMUSG00000062594 +66132 1110008L16Rik MGI:MGI:1913382|Ensembl:ENSMUSG00000021023|Vega:OTTMUSG00000044896 +66136 Znrd1 MGI:MGI:1913386|Ensembl:ENSMUSG00000036315|Vega:OTTMUSG00000037385 +66138 Wbscr22 MGI:MGI:1913388|Ensembl:ENSMUSG00000005378|Vega:OTTMUSG00000025995 +66139 Mymk MGI:MGI:1913389|Ensembl:ENSMUSG00000009214|Vega:OTTMUSG00000011849 +66140 Ska2 MGI:MGI:1913390|Ensembl:ENSMUSG00000020492|Vega:OTTMUSG00000001218 +66141 Ifitm3 MGI:MGI:1913391|Ensembl:ENSMUSG00000025492|Vega:OTTMUSG00000037675 +66142 Cox7b MGI:MGI:1913392|Ensembl:ENSMUSG00000031231|Vega:OTTMUSG00000018281 +66143 Eef1e1 MGI:MGI:1913393|Ensembl:ENSMUSG00000001707 +66144 Atp6v1f MGI:MGI:1913394|Ensembl:ENSMUSG00000004285|Vega:OTTMUSG00000023640 +66146 Tmem57 MGI:MGI:1913396|Ensembl:ENSMUSG00000028826|Vega:OTTMUSG00000011092 +66147 Necap2 MGI:MGI:1913397|Ensembl:ENSMUSG00000028923|Vega:OTTMUSG00000010080 +66148 Dnajc15 MGI:MGI:1913398|Ensembl:ENSMUSG00000022013 +66151 Prr13 MGI:MGI:1913401|Ensembl:ENSMUSG00000023048|Vega:OTTMUSG00000035145 +66152 Uqcr10 MGI:MGI:1913402|Ensembl:ENSMUSG00000059534|Vega:OTTMUSG00000005067 +66153 Fbxo36 MGI:MGI:1289192|Ensembl:ENSMUSG00000073633|Vega:OTTMUSG00000021470 +66154 Tmem14c MGI:MGI:1913404|Ensembl:ENSMUSG00000021361 +66155 Ufc1 MGI:MGI:1913405|Ensembl:ENSMUSG00000062963|Vega:OTTMUSG00000021650 +66156 Anapc11 MGI:MGI:1913406|Ensembl:ENSMUSG00000025135|Vega:OTTMUSG00000004083 +66158 Cxx1a MGI:MGI:1913408|Ensembl:ENSMUSG00000067925|Vega:OTTMUSG00000017360 +66161 Pop4 MGI:MGI:1913411|Ensembl:ENSMUSG00000030423|Vega:OTTMUSG00000058189 +66162 Bola2 MGI:MGI:1913412|Ensembl:ENSMUSG00000047721|Vega:OTTMUSG00000023279 +66163 Mrpl4 MGI:MGI:2137210|Ensembl:ENSMUSG00000003299|Vega:OTTMUSG00000063045 +66164 Nip7 MGI:MGI:1913414|Ensembl:ENSMUSG00000031917|Vega:OTTMUSG00000061931 +66165 Bccip MGI:MGI:1913415|Ensembl:ENSMUSG00000030983|Vega:OTTMUSG00000022582 +66166 S100a14 MGI:MGI:1913416|Ensembl:ENSMUSG00000042306|Vega:OTTMUSG00000052751 +66167 Tma7 MGI:MGI:1913417|Ensembl:ENSMUSG00000091537|Vega:OTTMUSG00000051198 +66168 Grina MGI:MGI:1913418|Ensembl:ENSMUSG00000022564 +66169 Tomm7 MGI:MGI:1913419|Ensembl:ENSMUSG00000028998|Vega:OTTMUSG00000028516 +66170 Chchd5 MGI:MGI:1913420|Ensembl:ENSMUSG00000037938|Vega:OTTMUSG00000015423 +66171 Pgls MGI:MGI:1913421|Ensembl:ENSMUSG00000031807|Vega:OTTMUSG00000033938 +66172 Med11 MGI:MGI:1913422|Ensembl:ENSMUSG00000018923|Vega:OTTMUSG00000006050 +66174 Nudt14 MGI:MGI:1913424|Ensembl:ENSMUSG00000002804 +66175 Mustn1 MGI:MGI:1913425|Ensembl:ENSMUSG00000042485 +66176 Nat9 MGI:MGI:1913426|Ensembl:ENSMUSG00000015542|Vega:OTTMUSG00000003643 +66177 Ubl5 MGI:MGI:1913427|Ensembl:ENSMUSG00000084786|Vega:OTTMUSG00000029130 +66179 Ogfod3 MGI:MGI:1913429|Ensembl:ENSMUSG00000025169|Vega:OTTMUSG00000004286 +66180 P3h4 MGI:MGI:1913430|Ensembl:ENSMUSG00000006931|Vega:OTTMUSG00000006272 +66181 Nop10 MGI:MGI:1913431|Ensembl:ENSMUSG00000027133|Vega:OTTMUSG00000015143 +66183 Sptssb MGI:MGI:1913433|Ensembl:ENSMUSG00000043461|Vega:OTTMUSG00000051554 +66184 Rps4l MGI:MGI:1913434|Ensembl:ENSMUSG00000063171 +66185 Virma MGI:MGI:1913435|Ensembl:ENSMUSG00000040720|Vega:OTTMUSG00000004468 +66190 Acer3 MGI:MGI:1913440|Ensembl:ENSMUSG00000030760|Vega:OTTMUSG00000030994 +66191 Ier3ip1 MGI:MGI:1913441|Ensembl:ENSMUSG00000090000|Vega:OTTMUSG00000033485 +66192 Lage3 MGI:MGI:1913442|Ensembl:ENSMUSG00000015289|Vega:OTTMUSG00000017697 +66193 Pithd1 MGI:MGI:1913443|Ensembl:ENSMUSG00000028669|Vega:OTTMUSG00000009845 +66194 Pycrl MGI:MGI:1913444|Ensembl:ENSMUSG00000022571 +66195 Lce1g MGI:MGI:1913445|Ensembl:ENSMUSG00000027919|Vega:OTTMUSG00000036824 +66196 Myo19 MGI:MGI:1913446|Ensembl:ENSMUSG00000020527|Vega:OTTMUSG00000001021 +66197 Cks2 MGI:MGI:1913447|Ensembl:ENSMUSG00000062248|Vega:OTTMUSG00000023833 +66198 Them5 MGI:MGI:1913448|Ensembl:ENSMUSG00000028148|Vega:OTTMUSG00000026636 +66199 Commd4 MGI:MGI:1913449|Ensembl:ENSMUSG00000032299|Vega:OTTMUSG00000063138 +66200 Commd6 MGI:MGI:1913450|Ensembl:ENSMUSG00000075486|Vega:OTTMUSG00000033464 +66201 Vta1 MGI:MGI:1913451|Ensembl:ENSMUSG00000019868|Vega:OTTMUSG00000031918 +66202 1110059G10Rik MGI:MGI:1913452|Ensembl:ENSMUSG00000032551|Vega:OTTMUSG00000031807 +66203 Lce1m MGI:MGI:1913453|Ensembl:ENSMUSG00000027912|Vega:OTTMUSG00000051908 +66204 Acyp1 MGI:MGI:1913454|Ensembl:ENSMUSG00000008822|Vega:OTTMUSG00000027677 +66205 Cd302 MGI:MGI:1913455|Ensembl:ENSMUSG00000060703|Vega:OTTMUSG00000012819 +66206 1110059E24Rik MGI:MGI:1913456|Ensembl:ENSMUSG00000035171|Vega:OTTMUSG00000042308 +66208 Nenf MGI:MGI:1913458|Ensembl:ENSMUSG00000037499|Vega:OTTMUSG00000021423 +66209 Inip MGI:MGI:1913459|Ensembl:ENSMUSG00000038544|Vega:OTTMUSG00000007409 +66211 Rpl3l MGI:MGI:1913461|Ensembl:ENSMUSG00000002500|Vega:OTTMUSG00000043586 +66212 Sec61b MGI:MGI:1913462|Ensembl:ENSMUSG00000053317|Vega:OTTMUSG00000006799 +66213 Med7 MGI:MGI:1913463|Ensembl:ENSMUSG00000020397|Vega:OTTMUSG00000005502 +66214 Rgcc MGI:MGI:1913464|Ensembl:ENSMUSG00000022018|Vega:OTTMUSG00000042059 +66218 Ndufb9 MGI:MGI:1913468|Ensembl:ENSMUSG00000022354 +66220 Zdhhc12 MGI:MGI:1913470|Ensembl:ENSMUSG00000015335|Vega:OTTMUSG00000016743 +66222 Serpinb1a MGI:MGI:1913472|Ensembl:ENSMUSG00000044734|Vega:OTTMUSG00000000694 +66223 Mrpl35 MGI:MGI:1913473|Ensembl:ENSMUSG00000052962|Vega:OTTMUSG00000023742 +66225 Llph MGI:MGI:1913475|Ensembl:ENSMUSG00000020224|Vega:OTTMUSG00000032589 +66226 Trappc2 MGI:MGI:1913476|Ensembl:ENSMUSG00000079317|Vega:OTTMUSG00000019550 +66229 Rpl7l1 MGI:MGI:1913479|Ensembl:ENSMUSG00000063888 +66230 Mrps28 MGI:MGI:1913480|Ensembl:ENSMUSG00000040269|Vega:OTTMUSG00000022361 +66231 Thoc7 MGI:MGI:1913481|Ensembl:ENSMUSG00000053453 +66233 Dmap1 MGI:MGI:1913483|Ensembl:ENSMUSG00000009640|Vega:OTTMUSG00000008650 +66234 Msmo1 MGI:MGI:1913484|Ensembl:ENSMUSG00000031604|Vega:OTTMUSG00000022600 +66235 Eif1ax MGI:MGI:1913485|Ensembl:ENSMUSG00000067194|Vega:OTTMUSG00000019437 +66236 1500011B03Rik MGI:MGI:1913486|Ensembl:ENSMUSG00000072694|Vega:OTTMUSG00000014592 +66237 Atp6v1g2 MGI:MGI:1913487|Ensembl:ENSMUSG00000024403|Vega:OTTMUSG00000031451 +66240 Kcne1l MGI:MGI:1913490|Ensembl:ENSMUSG00000090122|Vega:OTTMUSG00000018812 +66241 Tmem9 MGI:MGI:1913491|Ensembl:ENSMUSG00000026411|Vega:OTTMUSG00000029663 +66242 Mrps16 MGI:MGI:1913492|Ensembl:ENSMUSG00000049960 +66244 Nemf MGI:MGI:1918305|Ensembl:ENSMUSG00000020982 +66245 Hspbp1 MGI:MGI:1913495|Ensembl:ENSMUSG00000063802|Vega:OTTMUSG00000058444 +66246 Osgep MGI:MGI:1913496|Ensembl:ENSMUSG00000006289|Vega:OTTMUSG00000033803 +66248 Alg5 MGI:MGI:1913498|Ensembl:ENSMUSG00000036632|Vega:OTTMUSG00000028217 +66249 Pno1 MGI:MGI:1913499|Ensembl:ENSMUSG00000020116|Vega:OTTMUSG00000005193 +66251 Arfgap3 MGI:MGI:1913501|Ensembl:ENSMUSG00000054277 +66253 Aig1 MGI:MGI:1913503|Ensembl:ENSMUSG00000019806|Vega:OTTMUSG00000028019 +66254 Dimt1 MGI:MGI:1913504|Ensembl:ENSMUSG00000021692 +66255 Hsbp1l1 MGI:MGI:1913505|Ensembl:ENSMUSG00000078963 +66256 Ssr2 MGI:MGI:1913506|Ensembl:ENSMUSG00000041355|Vega:OTTMUSG00000052161 +66257 Nicn1 MGI:MGI:1913507|Ensembl:ENSMUSG00000032606|Vega:OTTMUSG00000050750 +66258 Mrps17 MGI:MGI:1913508|Ensembl:ENSMUSG00000034211|Vega:OTTMUSG00000027648 +66259 Camk2n1 MGI:MGI:1913509|Ensembl:ENSMUSG00000046447|Vega:OTTMUSG00000010002 +66260 Tmem54 MGI:MGI:1913510|Ensembl:ENSMUSG00000028786|Vega:OTTMUSG00000009629 +66261 Tm4sf20 MGI:MGI:1913511|Ensembl:ENSMUSG00000026149|Vega:OTTMUSG00000022140 +66262 Ing5 MGI:MGI:1922816|Ensembl:ENSMUSG00000026283|Vega:OTTMUSG00000048689 +66263 1810014B01Rik MGI:MGI:1913513|Ensembl:ENSMUSG00000097412 +66264 Ccdc28b MGI:MGI:1913514|Ensembl:ENSMUSG00000028795|Vega:OTTMUSG00000009526 +66266 Eapp MGI:MGI:1913516|Ensembl:ENSMUSG00000054302|Vega:OTTMUSG00000034925 +66268 Pigyl MGI:MGI:1913518|Ensembl:ENSMUSG00000010607|Vega:OTTMUSG00000034073 +66269 Tmed6 MGI:MGI:1913519|Ensembl:ENSMUSG00000031919|Vega:OTTMUSG00000061932 +66270 Retreg1 MGI:MGI:1913520|Ensembl:ENSMUSG00000022270 +66271 Tmem126a MGI:MGI:1913521|Ensembl:ENSMUSG00000030615|Vega:OTTMUSG00000031242 +66272 Cox16 MGI:MGI:1913522|Ensembl:ENSMUSG00000091803|Vega:OTTMUSG00000035308 +66273 Aamdc MGI:MGI:1913523|Ensembl:ENSMUSG00000035642|Vega:OTTMUSG00000032939 +66274 Lyrm9 MGI:MGI:1913524|Ensembl:ENSMUSG00000072640|Vega:OTTMUSG00000000131 +66276 1810009A15Rik MGI:MGI:1913526|Ensembl:ENSMUSG00000071653|Vega:OTTMUSG00000045539 +66277 Klf15 MGI:MGI:1929988|Ensembl:ENSMUSG00000030087|Vega:OTTMUSG00000022237 +66278 Smim20 MGI:MGI:1913528|Ensembl:ENSMUSG00000061461|Vega:OTTMUSG00000029648 +66279 Tmem218 MGI:MGI:1913529|Ensembl:ENSMUSG00000032121|Vega:OTTMUSG00000063044 +66280 1810028F09Rik MGI:MGI:1913530 +66282 Tma16 MGI:MGI:1913532|Ensembl:ENSMUSG00000025591|Vega:OTTMUSG00000030740 +66283 Gkn1 MGI:MGI:1913533|Ensembl:ENSMUSG00000030050|Vega:OTTMUSG00000057174 +66284 Gkn2 MGI:MGI:1913534|Ensembl:ENSMUSG00000030049|Vega:OTTMUSG00000057175 +66286 Sec11c MGI:MGI:1913536|Ensembl:ENSMUSG00000024516|Vega:OTTMUSG00000028234 +66289 Mptx1 MGI:MGI:1913539|Ensembl:ENSMUSG00000026531|Vega:OTTMUSG00000034865 +66290 Atp6v1g1 MGI:MGI:1913540|Ensembl:ENSMUSG00000039105|Vega:OTTMUSG00000000312 +66291 Smim8 MGI:MGI:1913541|Ensembl:ENSMUSG00000028295|Vega:OTTMUSG00000006463 +66292 Mrps21 MGI:MGI:1913542|Ensembl:ENSMUSG00000054312|Vega:OTTMUSG00000022175 +66293 1810032O08Rik MGI:MGI:1913543|Ensembl:ENSMUSG00000020812|Vega:OTTMUSG00000003951 +66294 Fam3a MGI:MGI:1913544|Ensembl:ENSMUSG00000031399|Vega:OTTMUSG00000017653 +66296 Haus2 MGI:MGI:1913546|Ensembl:ENSMUSG00000027285|Vega:OTTMUSG00000015622 +66297 Pantr1 MGI:MGI:1913547|Ensembl:ENSMUSG00000060424 +66298 Defa21 MGI:MGI:1913548|Ensembl:ENSMUSG00000074447|Vega:OTTMUSG00000019489 +66299 2610019N06Rik MGI:MGI:1913549 +66300 Inafm1 MGI:MGI:1913550|Ensembl:ENSMUSG00000091811|Vega:OTTMUSG00000060710 +66302 Rmdn1 MGI:MGI:1913552|Ensembl:ENSMUSG00000028229|Vega:OTTMUSG00000004720 +66306 Fam53c MGI:MGI:1913556|Ensembl:ENSMUSG00000034300 +66307 Isoc1 MGI:MGI:1913557|Ensembl:ENSMUSG00000024601 +66308 Mplkip MGI:MGI:1913558|Ensembl:ENSMUSG00000012429 +66309 Tmem128 MGI:MGI:1913559|Ensembl:ENSMUSG00000067365|Vega:OTTMUSG00000026725 +66310 Dpy30 MGI:MGI:1913560|Ensembl:ENSMUSG00000024067 +66311 Cenpw MGI:MGI:1913561|Ensembl:ENSMUSG00000075266|Vega:OTTMUSG00000063723 +66313 Smurf2 MGI:MGI:1913563|Ensembl:ENSMUSG00000018363|Vega:OTTMUSG00000003584 +66314 Tpd52l2 MGI:MGI:1913564|Ensembl:ENSMUSG00000000827|Vega:OTTMUSG00000016709 +66315 Senp7 MGI:MGI:1913565|Ensembl:ENSMUSG00000052917|Vega:OTTMUSG00000056146 +66317 Wdr61 MGI:MGI:1917493|Ensembl:ENSMUSG00000061559|Vega:OTTMUSG00000027395 +66320 Tmem208 MGI:MGI:1913570|Ensembl:ENSMUSG00000014856|Vega:OTTMUSG00000022553 +66321 1700008B11Rik MGI:MGI:1913571 +66322 Krt88 MGI:MGI:1913572|Ensembl:ENSMUSG00000063971 +66323 1700001K19Rik MGI:MGI:1913573|Ensembl:ENSMUSG00000056508 +66325 1700008H02Rik MGI:MGI:1913575 +66326 Dnajc5b MGI:MGI:1913576|Ensembl:ENSMUSG00000027606|Vega:OTTMUSG00000027803 +66328 Scp2d1 MGI:MGI:1913578|Ensembl:ENSMUSG00000027431|Vega:OTTMUSG00000004237 +66329 Susd3 MGI:MGI:1913579|Ensembl:ENSMUSG00000021384|Vega:OTTMUSG00000027688 +66330 1700020L24Rik MGI:MGI:1913580|Ensembl:ENSMUSG00000035085|Vega:OTTMUSG00000000935 +66332 1700018B24Rik MGI:MGI:1913582 +66333 Aqp11 MGI:MGI:1913583|Ensembl:ENSMUSG00000042797|Vega:OTTMUSG00000058568 +66334 1700025K04Rik MGI:MGI:1913584 +66335 Atp6v1c1 MGI:MGI:1913585|Ensembl:ENSMUSG00000022295 +66336 Cenpp MGI:MGI:1913586|Ensembl:ENSMUSG00000021391 +66337 Fam229b MGI:MGI:1913587|Ensembl:ENSMUSG00000051736|Vega:OTTMUSG00000032773 +66338 Cdrt4 MGI:MGI:1913588|Ensembl:ENSMUSG00000042200|Vega:OTTMUSG00000005881 +66340 Psenen MGI:MGI:1913590|Ensembl:ENSMUSG00000036835|Vega:OTTMUSG00000059364 +66341 Eid3 MGI:MGI:1913591|Ensembl:ENSMUSG00000109864|Vega:OTTMUSG00000060246 +66343 Tmem177 MGI:MGI:1913593|Ensembl:ENSMUSG00000036975|Vega:OTTMUSG00000022105 +66344 Lce3b MGI:MGI:1913594|Ensembl:ENSMUSG00000042031|Vega:OTTMUSG00000051904 +66346 1700029P11Rik MGI:MGI:1913596|Ensembl:ENSMUSG00000061633|Vega:OTTMUSG00000033621 +66349 Atp5sl MGI:MGI:1913599|Ensembl:ENSMUSG00000057229|Vega:OTTMUSG00000023377 +66350 Pla2g12a MGI:MGI:1913600|Ensembl:ENSMUSG00000027999|Vega:OTTMUSG00000054638 +66352 Blzf1 MGI:MGI:1201607|Ensembl:ENSMUSG00000026577|Vega:OTTMUSG00000029367 +66353 Riiad1 MGI:MGI:1913603|Ensembl:ENSMUSG00000028139|Vega:OTTMUSG00000034526 +66354 Snw1 MGI:MGI:1913604|Ensembl:ENSMUSG00000021039 +66355 Gmpr MGI:MGI:1913605|Ensembl:ENSMUSG00000000253|Vega:OTTMUSG00000023421 +66356 Knop1 MGI:MGI:1913606|Ensembl:ENSMUSG00000030980|Vega:OTTMUSG00000025702 +66357 Ostc MGI:MGI:1913607|Ensembl:ENSMUSG00000041084|Vega:OTTMUSG00000054747 +66358 Adprm MGI:MGI:1913608|Ensembl:ENSMUSG00000020910|Vega:OTTMUSG00000005917 +66359 Cox20 MGI:MGI:1913609|Ensembl:ENSMUSG00000026500|Vega:OTTMUSG00000022143 +66361 Zfand1 MGI:MGI:1913611|Ensembl:ENSMUSG00000039795|Vega:OTTMUSG00000022145 +66362 Exosc3 MGI:MGI:1913612|Ensembl:ENSMUSG00000028322|Vega:OTTMUSG00000007603 +66364 2310009A05Rik MGI:MGI:1913614 +66365 Ccdc90b MGI:MGI:1913615|Ensembl:ENSMUSG00000030613|Vega:OTTMUSG00000031425 +66366 Ergic3 MGI:MGI:1913616|Ensembl:ENSMUSG00000005881|Vega:OTTMUSG00000016019 +66367 2310022A10Rik MGI:MGI:1913617|Ensembl:ENSMUSG00000049643|Vega:OTTMUSG00000046071 +66368 Rtca MGI:MGI:1913618|Ensembl:ENSMUSG00000000339|Vega:OTTMUSG00000027075 +66369 Dus2 MGI:MGI:1913619|Ensembl:ENSMUSG00000031901|Vega:OTTMUSG00000031188 +66371 Chmp4c MGI:MGI:1913621|Ensembl:ENSMUSG00000027536|Vega:OTTMUSG00000027789 +66373 Lsm5 MGI:MGI:1913623|Ensembl:ENSMUSG00000091625|Vega:OTTMUSG00000039873 +66374 2310011J03Rik MGI:MGI:1913624|Ensembl:ENSMUSG00000020133|Vega:OTTMUSG00000019117 +66375 Dhrs7 MGI:MGI:1913625|Ensembl:ENSMUSG00000021094 +66376 LOC66376 - +66377 Ndufc1 MGI:MGI:1913627|Ensembl:ENSMUSG00000037152|Vega:OTTMUSG00000022022 +66379 Cox14 MGI:MGI:1913629|Ensembl:ENSMUSG00000023020 +66380 Krtap3-3 MGI:MGI:1913630|Ensembl:ENSMUSG00000069722|Vega:OTTMUSG00000004960 +66381 Rnf113a2 MGI:MGI:1913631|Ensembl:ENSMUSG00000098134|Vega:OTTMUSG00000043574 +66383 Iscu MGI:MGI:1913633|Ensembl:ENSMUSG00000025825|Vega:OTTMUSG00000025818 +66384 Srp19 MGI:MGI:1913634|Ensembl:ENSMUSG00000014504|Vega:OTTMUSG00000029748 +66385 Ppp1r7 MGI:MGI:1913635|Ensembl:ENSMUSG00000026275|Vega:OTTMUSG00000021853 +66387 Nudt8 MGI:MGI:1913637|Ensembl:ENSMUSG00000024869|Ensembl:ENSMUSG00000110949|Vega:OTTMUSG00000033429|Vega:OTTMUSG00000063565 +66388 Cutc MGI:MGI:1913638|Ensembl:ENSMUSG00000025193|Vega:OTTMUSG00000026395 +66390 Prelid3b MGI:MGI:1913640|Ensembl:ENSMUSG00000016257|Vega:OTTMUSG00000016514 +66391 Zbtb11os1 MGI:MGI:1913641|Ensembl:ENSMUSG00000102101 +66392 Prl2b1 MGI:MGI:1861444|Ensembl:ENSMUSG00000069258|Vega:OTTMUSG00000000639 +66394 Nosip MGI:MGI:1913644|Ensembl:ENSMUSG00000003421|Vega:OTTMUSG00000023493 +66395 Ahnak MGI:MGI:1316648|Ensembl:ENSMUSG00000069833 +66396 Ccdc82 MGI:MGI:1913646|Ensembl:ENSMUSG00000079084|Vega:OTTMUSG00000062417 +66397 Sar1b MGI:MGI:1913647|Ensembl:ENSMUSG00000020386|Vega:OTTMUSG00000005609 +66398 Commd5 MGI:MGI:1913648|Ensembl:ENSMUSG00000055041|Vega:OTTMUSG00000023726 +66399 Tsfm MGI:MGI:1913649|Ensembl:ENSMUSG00000040521|Vega:OTTMUSG00000030579 +66400 Alkbh7 MGI:MGI:1913650|Ensembl:ENSMUSG00000002661|Vega:OTTMUSG00000028993 +66401 Nudt2 MGI:MGI:1913651|Ensembl:ENSMUSG00000028443|Vega:OTTMUSG00000006659 +66402 Sln MGI:MGI:1913652|Ensembl:ENSMUSG00000042045|Vega:OTTMUSG00000063195 +66403 Asf1a MGI:MGI:1913653|Ensembl:ENSMUSG00000019857 +66404 Rtfdc1 MGI:MGI:1913654|Ensembl:ENSMUSG00000027502|Vega:OTTMUSG00000016150 +66405 Mcts2 MGI:MGI:1913655|Ensembl:ENSMUSG00000042814|Vega:OTTMUSG00000015819 +66406 Sac3d1 MGI:MGI:1913656|Ensembl:ENSMUSG00000024790 +66407 Mrps15 MGI:MGI:1913657|Ensembl:ENSMUSG00000028861|Vega:OTTMUSG00000009293 +66408 Aptx MGI:MGI:1913658|Ensembl:ENSMUSG00000028411|Vega:OTTMUSG00000006564 +66409 Rsl1d1 MGI:MGI:1913659|Ensembl:ENSMUSG00000005846|Vega:OTTMUSG00000026463 +66410 Mterf3 MGI:MGI:1913660|Ensembl:ENSMUSG00000021519|Vega:OTTMUSG00000037039 +66411 Tbcb MGI:MGI:1913661|Ensembl:ENSMUSG00000006095|Vega:OTTMUSG00000023327 +66412 Arrdc4 MGI:MGI:1913662|Ensembl:ENSMUSG00000042659|Vega:OTTMUSG00000029424 +66413 Psmd6 MGI:MGI:1913663|Ensembl:ENSMUSG00000021737|Vega:OTTMUSG00000027779 +66414 Ndufa12 MGI:MGI:1913664|Ensembl:ENSMUSG00000020022|Vega:OTTMUSG00000030989 +66416 Ndufa7 MGI:MGI:1913666|Ensembl:ENSMUSG00000041881|Vega:OTTMUSG00000037210 +66419 Mrpl11 MGI:MGI:2137215|Ensembl:ENSMUSG00000024902 +66420 Polr2e MGI:MGI:1913670|Ensembl:ENSMUSG00000004667|Vega:OTTMUSG00000019133 +66421 2410004B18Rik MGI:MGI:1913671|Ensembl:ENSMUSG00000036873|Vega:OTTMUSG00000022483 +66422 Dctpp1 MGI:MGI:1913672|Ensembl:ENSMUSG00000042462|Vega:OTTMUSG00000029401 +66423 Coprs MGI:MGI:1913673|Ensembl:ENSMUSG00000031458|Vega:OTTMUSG00000060790 +66425 Pcp4l1 MGI:MGI:1913675|Ensembl:ENSMUSG00000038370|Vega:OTTMUSG00000021662 +66427 Cyb5b MGI:MGI:1913677|Ensembl:ENSMUSG00000031924|Vega:OTTMUSG00000061933 +66431 Oxld1 MGI:MGI:1913681|Ensembl:ENSMUSG00000039670|Vega:OTTMUSG00000004185 +66432 Slc7a6os MGI:MGI:1916951|Ensembl:ENSMUSG00000033106|Vega:OTTMUSG00000061945 +66433 Chchd7 MGI:MGI:1913683|Ensembl:ENSMUSG00000042198|Vega:OTTMUSG00000004405 +66435 Uggt2 MGI:MGI:1913685|Ensembl:ENSMUSG00000042104|Vega:OTTMUSG00000033561 +66437 Fis1 MGI:MGI:1913687|Ensembl:ENSMUSG00000019054|Vega:OTTMUSG00000023394 +66438 Hamp2 MGI:MGI:2153530|Ensembl:ENSMUSG00000056978|Vega:OTTMUSG00000058019 +66439 Borcs7 MGI:MGI:1913689|Ensembl:ENSMUSG00000062376 +66440 Cdc26 MGI:MGI:1913690|Ensembl:ENSMUSG00000066149|Vega:OTTMUSG00000014381 +66441 Magohb MGI:MGI:1913691|Ensembl:ENSMUSG00000030188|Vega:OTTMUSG00000038227 +66442 Spc25 MGI:MGI:1913692|Ensembl:ENSMUSG00000005233|Vega:OTTMUSG00000012970 +66443 Tnfaip8l1 MGI:MGI:1913693|Ensembl:ENSMUSG00000044469|Vega:OTTMUSG00000035458 +66445 Cyc1 MGI:MGI:1913695|Ensembl:ENSMUSG00000022551 +66446 Exosc7 MGI:MGI:1913696|Ensembl:ENSMUSG00000025785|Vega:OTTMUSG00000034189 +66447 Mgst3 MGI:MGI:1913697|Ensembl:ENSMUSG00000026688|Vega:OTTMUSG00000022623 +66448 Mrpl20 MGI:MGI:2137221|Ensembl:ENSMUSG00000029066|Vega:OTTMUSG00000010847 +66449 Pam16 MGI:MGI:1913699|Ensembl:ENSMUSG00000014301|Vega:OTTMUSG00000026710 +66451 2610528J11Rik MGI:MGI:1913701|Ensembl:ENSMUSG00000028536|Vega:OTTMUSG00000008797 +66454 Nmnat1 MGI:MGI:1913704|Ensembl:ENSMUSG00000028992|Vega:OTTMUSG00000010262 +66455 Cnpy4 MGI:MGI:1913705|Ensembl:ENSMUSG00000036968|Vega:OTTMUSG00000022707 +66456 2810001G20Rik MGI:MGI:1913706|Ensembl:ENSMUSG00000087497 +66457 2810002D19Rik MGI:MGI:1913707 +66459 Pyurf MGI:MGI:1913709|Ensembl:ENSMUSG00000043162|Vega:OTTMUSG00000024212 +66460 Sys1 MGI:MGI:1913710|Ensembl:ENSMUSG00000045503|Vega:OTTMUSG00000001089 +66461 Ptpmt1 MGI:MGI:1913711 +66462 2810428I15Rik MGI:MGI:1913712|Ensembl:ENSMUSG00000058833|Vega:OTTMUSG00000034074 +66464 Taf12 MGI:MGI:1913714|Ensembl:ENSMUSG00000028899|Vega:OTTMUSG00000011107 +66467 Gtf2h5 MGI:MGI:107227|Ensembl:ENSMUSG00000034345|Vega:OTTMUSG00000024049 +66468 Ska1 MGI:MGI:1913718|Ensembl:ENSMUSG00000036223 +66469 Fam213b MGI:MGI:1913719|Ensembl:ENSMUSG00000029059|Vega:OTTMUSG00000010466 +66471 Anp32e MGI:MGI:1913721|Ensembl:ENSMUSG00000015749|Vega:OTTMUSG00000035336 +66473 Ctrb1 MGI:MGI:88559|Ensembl:ENSMUSG00000031957|Vega:OTTMUSG00000061801 +66475 Rps23 MGI:MGI:1913725|Ensembl:ENSMUSG00000049517 +66477 Usmg5 MGI:MGI:1891435|Ensembl:ENSMUSG00000071528 +66479 1700029F12Rik MGI:MGI:1913729|Ensembl:ENSMUSG00000052075 +66480 Rpl15 MGI:MGI:1913730|Ensembl:ENSMUSG00000012405|Vega:OTTMUSG00000022948 +66481 Rps21 MGI:MGI:1913731|Ensembl:ENSMUSG00000039001|Vega:OTTMUSG00000016278 +66482 Exoc2 MGI:MGI:1913732|Ensembl:ENSMUSG00000021357|Vega:OTTMUSG00000000674 +66483 Rpl36al MGI:MGI:1913733|Ensembl:ENSMUSG00000049751|Vega:OTTMUSG00000023813 +66487 Smim4 MGI:MGI:1913737|Ensembl:ENSMUSG00000058351|Vega:OTTMUSG00000057521 +66488 Fam136a MGI:MGI:1913738|Ensembl:ENSMUSG00000057497|Vega:OTTMUSG00000056432 +66489 Rpl35 MGI:MGI:1913739|Ensembl:ENSMUSG00000062997|Vega:OTTMUSG00000012348 +66491 Polr2l MGI:MGI:1913741|Ensembl:ENSMUSG00000038489|Vega:OTTMUSG00000028947 +66492 Zmat2 MGI:MGI:1913742|Ensembl:ENSMUSG00000001383 +66493 Mrpl51 MGI:MGI:1913743|Ensembl:ENSMUSG00000030335|Vega:OTTMUSG00000024231 +66494 Prelid1 MGI:MGI:1913744|Ensembl:ENSMUSG00000021486 +66495 Ndufb3 MGI:MGI:1913745|Ensembl:ENSMUSG00000026032|Vega:OTTMUSG00000026621 +66496 Ppdpf MGI:MGI:1913746|Ensembl:ENSMUSG00000016344|Vega:OTTMUSG00000016566 +66497 Cmss1 MGI:MGI:1913747|Ensembl:ENSMUSG00000022748 +66498 Dda1 MGI:MGI:1913748|Ensembl:ENSMUSG00000074247|Vega:OTTMUSG00000032855 +66500 Slc30a7 MGI:MGI:1913750|Ensembl:ENSMUSG00000054414|Vega:OTTMUSG00000054442 +66501 1700029H14Rik MGI:MGI:1913751|Ensembl:ENSMUSG00000031452|Vega:OTTMUSG00000033371 +66503 1810034E14Rik MGI:MGI:1913753|Ensembl:ENSMUSG00000097101 +66505 Zmynd11 MGI:MGI:1913755|Ensembl:ENSMUSG00000021156|Vega:OTTMUSG00000017437 +66506 Psmg3 MGI:MGI:1913756|Ensembl:ENSMUSG00000029551|Vega:OTTMUSG00000043500 +66508 Lamtor1 MGI:MGI:1913758|Ensembl:ENSMUSG00000030842|Vega:OTTMUSG00000052219 +66510 Rnf181 MGI:MGI:1913760|Ensembl:ENSMUSG00000055850|Vega:OTTMUSG00000023081 +66511 Chtop MGI:MGI:1913761|Ensembl:ENSMUSG00000001017|Vega:OTTMUSG00000021869 +66513 Tab1 MGI:MGI:1913763|Ensembl:ENSMUSG00000022414 +66514 Asrgl1 MGI:MGI:1913764|Ensembl:ENSMUSG00000024654|Vega:OTTMUSG00000028355 +66515 Cul7 MGI:MGI:1913765|Ensembl:ENSMUSG00000038545|Vega:OTTMUSG00000024273 +66520 2610001J05Rik MGI:MGI:1913770 +66521 Rwdd1 MGI:MGI:1913771|Ensembl:ENSMUSG00000019782|Vega:OTTMUSG00000027976 +66522 Pgpep1 MGI:MGI:1913772|Ensembl:ENSMUSG00000056204|Vega:OTTMUSG00000061450 +66523 2810004N23Rik MGI:MGI:1913773|Ensembl:ENSMUSG00000031984|Vega:OTTMUSG00000061568 +66525 Timm50 MGI:MGI:1913775|Ensembl:ENSMUSG00000003438|Vega:OTTMUSG00000029548 +66526 Tceanc2 MGI:MGI:1913776|Ensembl:ENSMUSG00000028619|Vega:OTTMUSG00000008470 +66528 Smim5 MGI:MGI:1913778|Ensembl:ENSMUSG00000048442|Vega:OTTMUSG00000003651 +66530 Ubxn6 MGI:MGI:1913780|Ensembl:ENSMUSG00000019578|Vega:OTTMUSG00000033034 +66531 Cmc2 MGI:MGI:1913781|Ensembl:ENSMUSG00000014633|Vega:OTTMUSG00000018679 +66532 Rep15 MGI:MGI:1913782|Ensembl:ENSMUSG00000040121|Vega:OTTMUSG00000057289 +66533 2310050C09Rik MGI:MGI:1913783|Ensembl:ENSMUSG00000090314|Vega:OTTMUSG00000051863 +66536 Nipsnap3b MGI:MGI:1913786|Ensembl:ENSMUSG00000015247|Vega:OTTMUSG00000007156 +66537 Pomp MGI:MGI:1913787|Ensembl:ENSMUSG00000029649|Vega:OTTMUSG00000055798 +66538 Rps19bp1 MGI:MGI:1913788|Ensembl:ENSMUSG00000051518 +66540 Fam107b MGI:MGI:1913790|Ensembl:ENSMUSG00000026655|Vega:OTTMUSG00000010781 +66541 Immp1l MGI:MGI:1913791|Ensembl:ENSMUSG00000042670|Vega:OTTMUSG00000015172 +66547 2010203P06Rik MGI:MGI:1913797 +66548 Adamtsl5 MGI:MGI:1913798|Ensembl:ENSMUSG00000043822|Vega:OTTMUSG00000019127 +66549 Aggf1 MGI:MGI:1913799|Ensembl:ENSMUSG00000021681|Vega:OTTMUSG00000030737 +66550 2010109N18Rik MGI:MGI:1913800 +66552 Sppl2a MGI:MGI:1913802|Ensembl:ENSMUSG00000027366|Vega:OTTMUSG00000015962 +66556 Drap1 MGI:MGI:1913806|Ensembl:ENSMUSG00000024914|Vega:OTTMUSG00000021556 +66557 Bpifb2 MGI:MGI:1913807|Ensembl:ENSMUSG00000027481|Vega:OTTMUSG00000016857 +66559 Metap1d MGI:MGI:1913809|Ensembl:ENSMUSG00000041921|Vega:OTTMUSG00000013201 +66561 Teddm3 MGI:MGI:1913811|Ensembl:ENSMUSG00000090356|Vega:OTTMUSG00000046188 +66566 Ntpcr MGI:MGI:1913816|Ensembl:ENSMUSG00000031851|Vega:OTTMUSG00000032845 +66567 2510022D24Rik MGI:MGI:1913817 +66568 Rwdd3 MGI:MGI:1920420|Ensembl:ENSMUSG00000028133|Vega:OTTMUSG00000035255 +66569 Gdpd1 MGI:MGI:1913819|Ensembl:ENSMUSG00000061666|Vega:OTTMUSG00000001223 +66570 Cenpm MGI:MGI:1913820|Ensembl:ENSMUSG00000068101 +66573 Dzip1 MGI:MGI:1914311|Ensembl:ENSMUSG00000042156 +66574 2510017J16Rik MGI:MGI:1913824 +66576 Uqcrh MGI:MGI:1913826|Ensembl:ENSMUSG00000063882|Vega:OTTMUSG00000008727 +66578 Mis18a MGI:MGI:1913828|Ensembl:ENSMUSG00000022978|Vega:OTTMUSG00000019967 +66579 2610007O09Rik MGI:MGI:1913829 +66580 Esf1 MGI:MGI:1913830|Ensembl:ENSMUSG00000045624|Vega:OTTMUSG00000015586 +66583 Exosc1 MGI:MGI:1913833|Ensembl:ENSMUSG00000034321 +66584 2610104F20Rik MGI:MGI:1913834 +66585 Snrnp40 MGI:MGI:1913835|Ensembl:ENSMUSG00000074088|Vega:OTTMUSG00000042995 +66586 Crls1 MGI:MGI:1913836|Ensembl:ENSMUSG00000027357|Vega:OTTMUSG00000015664 +66587 Fastk MGI:MGI:1913837|Ensembl:ENSMUSG00000028959|Vega:OTTMUSG00000024187 +66588 Cmpk1 MGI:MGI:1913838|Ensembl:ENSMUSG00000028719|Vega:OTTMUSG00000008585 +66589 Ube2v1 MGI:MGI:1913839|Ensembl:ENSMUSG00000078923|Vega:OTTMUSG00000001159 +66590 Farsa MGI:MGI:1913840|Ensembl:ENSMUSG00000003808|Vega:OTTMUSG00000022260 +66591 Mad2l1bp MGI:MGI:1913841|Ensembl:ENSMUSG00000034509 +66592 Stoml2 MGI:MGI:1913842|Ensembl:ENSMUSG00000028455|Vega:OTTMUSG00000006709 +66593 Diablo MGI:MGI:1913843|Ensembl:ENSMUSG00000029433|Vega:OTTMUSG00000025948 +66594 Uqcr11 MGI:MGI:1913844|Ensembl:ENSMUSG00000020163|Vega:OTTMUSG00000019123 +66595 Aste1 MGI:MGI:1913845|Ensembl:ENSMUSG00000032567|Vega:OTTMUSG00000022639 +66596 Gtf3a MGI:MGI:1913846|Ensembl:ENSMUSG00000016503|Vega:OTTMUSG00000024608 +66597 Trim13 MGI:MGI:1913847|Ensembl:ENSMUSG00000035235 +66599 Rdm1 MGI:MGI:1913849|Ensembl:ENSMUSG00000010362|Vega:OTTMUSG00000002934 +66601 Tmigd1 MGI:MGI:1913851|Ensembl:ENSMUSG00000020839|Vega:OTTMUSG00000006243 +66602 1700020I14Rik MGI:MGI:1913852|Ensembl:ENSMUSG00000085438 +66603 Gemin2 MGI:MGI:1913853|Ensembl:ENSMUSG00000060121|Vega:OTTMUSG00000044350 +66605 1700017N19Rik MGI:MGI:1913855|Ensembl:ENSMUSG00000056912|Vega:OTTMUSG00000045119 +66606 Lrrc57 MGI:MGI:1913856|Ensembl:ENSMUSG00000027286|Vega:OTTMUSG00000015625 +66607 Ms4a4d MGI:MGI:1913857|Ensembl:ENSMUSG00000024678|Vega:OTTMUSG00000028272 +66609 Cryzl1 MGI:MGI:1913859|Ensembl:ENSMUSG00000058240|Vega:OTTMUSG00000027250 +66610 Abi3 MGI:MGI:1913860|Ensembl:ENSMUSG00000018381|Vega:OTTMUSG00000001756 +66611 Ribc1 MGI:MGI:1913861|Ensembl:ENSMUSG00000025257|Vega:OTTMUSG00000019649 +66612 Ormdl3 MGI:MGI:1913862|Ensembl:ENSMUSG00000038150|Vega:OTTMUSG00000006371 +66614 Gpatch4 MGI:MGI:1913864|Ensembl:ENSMUSG00000028069|Vega:OTTMUSG00000051869 +66615 Atg4b MGI:MGI:1913865|Ensembl:ENSMUSG00000026280|Vega:OTTMUSG00000032629 +66616 Snx9 MGI:MGI:1913866|Ensembl:ENSMUSG00000002365 +66617 Ntmt1 MGI:MGI:1913867|Ensembl:ENSMUSG00000026857|Vega:OTTMUSG00000011871 +66618 Snrnp27 MGI:MGI:1913868|Ensembl:ENSMUSG00000001158|Vega:OTTMUSG00000024139 +66620 Pantr2 MGI:MGI:1913870|Ensembl:ENSMUSG00000097063 +66622 Ubr7 MGI:MGI:1913872|Ensembl:ENSMUSG00000041712 +66624 Spcs2 MGI:MGI:1913874|Ensembl:ENSMUSG00000035227|Vega:OTTMUSG00000059051 +66625 Pnisr MGI:MGI:1913875|Ensembl:ENSMUSG00000028248|Vega:OTTMUSG00000004739 +66626 Cdip1 MGI:MGI:1913876|Ensembl:ENSMUSG00000004071|Vega:OTTMUSG00000026631 +66627 Ogfod2 MGI:MGI:1913877|Ensembl:ENSMUSG00000023707|Vega:OTTMUSG00000028870 +66628 Thg1l MGI:MGI:1913878|Ensembl:ENSMUSG00000011254|Vega:OTTMUSG00000005481 +66629 Golph3 MGI:MGI:1913879|Ensembl:ENSMUSG00000022200 +66631 Mfsd14b MGI:MGI:1913881|Ensembl:ENSMUSG00000038212|Vega:OTTMUSG00000033001 +66632 Dph6 MGI:MGI:1913882|Ensembl:ENSMUSG00000057147|Vega:OTTMUSG00000014824 +66634 Mcm8 MGI:MGI:1913884|Ensembl:ENSMUSG00000027353|Vega:OTTMUSG00000015646 +66637 Tsen15 MGI:MGI:1913887|Ensembl:ENSMUSG00000014980|Vega:OTTMUSG00000034856 +66638 5730458M16Rik MGI:MGI:1913888 +66641 Sike1 MGI:MGI:1913891|Ensembl:ENSMUSG00000027854|Vega:OTTMUSG00000028830 +66642 Ctnnbl1 MGI:MGI:1913892|Ensembl:ENSMUSG00000027649|Vega:OTTMUSG00000015882 +66643 Lix1 MGI:MGI:1913893|Ensembl:ENSMUSG00000047786|Vega:OTTMUSG00000031513 +66645 Pspc1 MGI:MGI:1913895|Ensembl:ENSMUSG00000021938|Vega:OTTMUSG00000035519 +66646 Rpe MGI:MGI:1913896|Ensembl:ENSMUSG00000026005|Vega:OTTMUSG00000021851 +66647 Nsmce3 MGI:MGI:1913897|Ensembl:ENSMUSG00000070520|Vega:OTTMUSG00000031051 +66648 Tpgs2 MGI:MGI:1913898|Ensembl:ENSMUSG00000024269|Vega:OTTMUSG00000033986 +66650 Nepn MGI:MGI:1913900|Ensembl:ENSMUSG00000038624 +66653 Brf2 MGI:MGI:1913903|Ensembl:ENSMUSG00000031487|Vega:OTTMUSG00000060988 +66654 Tex12 MGI:MGI:1913904|Ensembl:ENSMUSG00000032065|Vega:OTTMUSG00000063070 +66656 Eef1d MGI:MGI:1913906|Ensembl:ENSMUSG00000055762|Vega:OTTMUSG00000019797 +66658 Ccdc51 MGI:MGI:1913908|Ensembl:ENSMUSG00000025645|Vega:OTTMUSG00000051046 +66659 Acp6 MGI:MGI:1931010|Ensembl:ENSMUSG00000028093|Vega:OTTMUSG00000022388 +66660 Sltm MGI:MGI:1913910|Ensembl:ENSMUSG00000032212|Vega:OTTMUSG00000063624 +66661 Srp72 MGI:MGI:1333795|Ensembl:ENSMUSG00000036323|Vega:OTTMUSG00000026549 +66662 Fbxl12os MGI:MGI:1913912|Ensembl:ENSMUSG00000062470 +66663 Uba5 MGI:MGI:1913913|Ensembl:ENSMUSG00000032557|Vega:OTTMUSG00000027430 +66664 Tmem41a MGI:MGI:1913914|Ensembl:ENSMUSG00000022856 +66665 Msantd3 MGI:MGI:1913915|Ensembl:ENSMUSG00000039693|Vega:OTTMUSG00000006842 +66667 Hspbap1 MGI:MGI:1913917|Ensembl:ENSMUSG00000022849 +66671 Ccnh MGI:MGI:1913921|Ensembl:ENSMUSG00000021548|Vega:OTTMUSG00000035504 +66673 Sorcs3 MGI:MGI:1913923|Ensembl:ENSMUSG00000063434 +66674 Spryd7 MGI:MGI:1913924|Ensembl:ENSMUSG00000021930|Vega:OTTMUSG00000027842 +66676 Tmed7 MGI:MGI:1913926|Ensembl:ENSMUSG00000033184|Vega:OTTMUSG00000033481 +66679 Rae1 MGI:MGI:1913929|Ensembl:ENSMUSG00000027509|Vega:OTTMUSG00000016688 +66680 Oser1 MGI:MGI:1913930|Ensembl:ENSMUSG00000035399|Vega:OTTMUSG00000001066 +66681 Pgm1 MGI:MGI:97564|Ensembl:ENSMUSG00000029171|Vega:OTTMUSG00000026404 +66682 Trappc5 MGI:MGI:1913932|Ensembl:ENSMUSG00000040236|Vega:OTTMUSG00000032876 +66684 Tceal8 MGI:MGI:1913934|Ensembl:ENSMUSG00000051579|Vega:OTTMUSG00000018779 +66686 Dcbld1 MGI:MGI:1913936|Ensembl:ENSMUSG00000019891 +66687 Tbc1d15 MGI:MGI:1913937|Ensembl:ENSMUSG00000020130 +66689 Klhl28 MGI:MGI:1913939|Ensembl:ENSMUSG00000020948 +66690 Tmem186 MGI:MGI:1913940|Ensembl:ENSMUSG00000043140|Vega:OTTMUSG00000025205 +66691 Gapvd1 MGI:MGI:1913941|Ensembl:ENSMUSG00000026867|Vega:OTTMUSG00000012001 +66694 Uqcrfs1 MGI:MGI:1913944|Ensembl:ENSMUSG00000038462|Vega:OTTMUSG00000000670 +66695 Aspn MGI:MGI:1913945|Ensembl:ENSMUSG00000021388|Vega:OTTMUSG00000063427 +66696 Snx31 MGI:MGI:1913946|Ensembl:ENSMUSG00000013611|Vega:OTTMUSG00000023930 +66700 Chmp3 MGI:MGI:1913950|Ensembl:ENSMUSG00000053119|Vega:OTTMUSG00000023566 +66701 Spryd4 MGI:MGI:1913951|Ensembl:ENSMUSG00000051346 +66703 4921504P13Rik MGI:MGI:1913953 +66704 Rbm4b MGI:MGI:1913954|Ensembl:ENSMUSG00000033760|Vega:OTTMUSG00000043549 +66705 Dnase1l2 MGI:MGI:1913955|Ensembl:ENSMUSG00000024136|Vega:OTTMUSG00000029900 +66706 Ndufaf3 MGI:MGI:1913956|Ensembl:ENSMUSG00000070283|Vega:OTTMUSG00000050764 +66707 Nkapl MGI:MGI:1913957|Ensembl:ENSMUSG00000059395|Vega:OTTMUSG00000000420 +66708 Krtap3-2 MGI:MGI:1913958|Ensembl:ENSMUSG00000069721|Vega:OTTMUSG00000004967 +66709 4921507G05Rik MGI:MGI:1913959 +66711 Sbds MGI:MGI:1913961|Ensembl:ENSMUSG00000025337|Vega:OTTMUSG00000027908 +66712 Spesp1 MGI:MGI:1913962|Ensembl:ENSMUSG00000046846|Vega:OTTMUSG00000062535 +66713 Actr2 MGI:MGI:1913963|Ensembl:ENSMUSG00000020152|Vega:OTTMUSG00000005221 +66714 4921524J17Rik MGI:MGI:1913964|Ensembl:ENSMUSG00000036934|Vega:OTTMUSG00000061418 +66715 Henmt1 MGI:MGI:1913965|Ensembl:ENSMUSG00000045662|Vega:OTTMUSG00000007288 +66716 Ccer1 MGI:MGI:1913966|Ensembl:ENSMUSG00000047025 +66717 Ccdc96 MGI:MGI:1913967|Ensembl:ENSMUSG00000050677|Vega:OTTMUSG00000028004 +66719 4921522P10Rik MGI:MGI:1913969 +66720 Klhl10 MGI:MGI:2181067|Ensembl:ENSMUSG00000001558|Vega:OTTMUSG00000006277 +66722 Spag16 MGI:MGI:1913972|Ensembl:ENSMUSG00000053153|Vega:OTTMUSG00000034211 +66724 Tab3 MGI:MGI:1913974|Ensembl:ENSMUSG00000035476|Vega:OTTMUSG00000017925 +66725 Lrrk2 MGI:MGI:1913975|Ensembl:ENSMUSG00000036273|Vega:OTTMUSG00000020864 +66727 Hrasls5 MGI:MGI:1913977|Ensembl:ENSMUSG00000024973|Vega:OTTMUSG00000028354 +66729 Ankrd61 MGI:MGI:1913979|Ensembl:ENSMUSG00000029607|Vega:OTTMUSG00000025501 +66730 4921531C22Rik MGI:MGI:1913980|Ensembl:ENSMUSG00000085704 +66732 4921530L21Rik MGI:MGI:1913982|Ensembl:ENSMUSG00000034689 +66733 Kcng4 MGI:MGI:1913983|Ensembl:ENSMUSG00000045246|Vega:OTTMUSG00000033798 +66734 Map1lc3a MGI:MGI:1915661|Ensembl:ENSMUSG00000027602|Vega:OTTMUSG00000016007 +66736 Emc2 MGI:MGI:1913986|Ensembl:ENSMUSG00000022337 +66737 4921534H16Rik MGI:MGI:1913987|Ensembl:ENSMUSG00000090255 +66740 4931417E11Rik MGI:MGI:1913990|Ensembl:ENSMUSG00000056197 +66742 Cypt1 MGI:MGI:3616441|Ensembl:ENSMUSG00000023257|Vega:OTTMUSG00000016926 +66743 Rnf220 MGI:MGI:1913993|Ensembl:ENSMUSG00000028677|Vega:OTTMUSG00000008570 +66745 Trpd52l3 MGI:MGI:1913995|Ensembl:ENSMUSG00000024815 +66747 4933400A11Rik MGI:MGI:1913997|Ensembl:ENSMUSG00000055357|Vega:OTTMUSG00000019598 +66748 Erich2 MGI:MGI:1913998|Ensembl:ENSMUSG00000075302|Vega:OTTMUSG00000033267 +66749 4933406L23Rik MGI:MGI:1913999 +66752 4933404O12Rik MGI:MGI:1914002|Ensembl:ENSMUSG00000097908 +66753 Erlec1 MGI:MGI:1914003|Ensembl:ENSMUSG00000020311|Vega:OTTMUSG00000005350 +66755 4933415F23Rik MGI:MGI:1914005|Ensembl:ENSMUSG00000073730|Vega:OTTMUSG00000046242 +66756 Cfap97 MGI:MGI:1914006|Ensembl:ENSMUSG00000031631|Vega:OTTMUSG00000024662 +66757 Adat2 MGI:MGI:1914007|Ensembl:ENSMUSG00000019808|Vega:OTTMUSG00000020826 +66758 Zfp474 MGI:MGI:1914008|Ensembl:ENSMUSG00000046886|Vega:OTTMUSG00000060762 +66759 4933425D22Rik MGI:MGI:1914009 +66760 Sox5os3 MGI:MGI:1914010|Ensembl:ENSMUSG00000085785 +66761 4933417A18Rik MGI:MGI:1914011|Ensembl:ENSMUSG00000021415|Vega:OTTMUSG00000034503 +66763 4933425L06Rik MGI:MGI:1914013|Ensembl:ENSMUSG00000021718|Vega:OTTMUSG00000022973 +66764 4933424N20Rik MGI:MGI:1914014 +66765 4933411K16Rik MGI:MGI:1914015|Ensembl:ENSMUSG00000090369|Vega:OTTMUSG00000035807 +66766 Tmem239 MGI:MGI:1914016|Ensembl:ENSMUSG00000049692|Vega:OTTMUSG00000015507 +66768 Pacrgl MGI:MGI:1914018|Ensembl:ENSMUSG00000029089|Vega:OTTMUSG00000042186 +66769 4933427E11Rik MGI:MGI:1914019|Ensembl:ENSMUSG00000044276 +66770 4933429O19Rik MGI:MGI:1914020 +66771 Gid4 MGI:MGI:1914021|Ensembl:ENSMUSG00000018415|Vega:OTTMUSG00000005814 +66772 Asb17 MGI:MGI:1914022|Ensembl:ENSMUSG00000038997|Vega:OTTMUSG00000026572 +66773 Gm17019 MGI:MGI:4868370|Ensembl:ENSMUSG00000091897|Vega:OTTMUSG00000036597 +66774 Carlr MGI:MGI:1914024|Ensembl:ENSMUSG00000097638 +66775 Hacd4 MGI:MGI:1914025|Ensembl:ENSMUSG00000028497|Vega:OTTMUSG00000007653 +66776 Pisd-ps3 MGI:MGI:1914026 +66779 4933432I09Rik MGI:MGI:1914029 +66780 4933436I01Rik MGI:MGI:1914030|Ensembl:ENSMUSG00000025288|Vega:OTTMUSG00000017723 +66781 4933437F24Rik MGI:MGI:1914031 +66783 Aknaos MGI:MGI:1914033 +66784 Fam187a MGI:MGI:1914034|Ensembl:ENSMUSG00000075510|Vega:OTTMUSG00000034309 +66785 4933433G08Rik MGI:MGI:1914035|Ensembl:ENSMUSG00000111807 +66786 Olfr701 MGI:MGI:3030535|Ensembl:ENSMUSG00000036744|Vega:OTTMUSG00000059682 +66787 Gskip MGI:MGI:1914037|Ensembl:ENSMUSG00000044715 +66788 5430414B12Rik MGI:MGI:1914038 +66789 Alg14 MGI:MGI:1914039|Ensembl:ENSMUSG00000039887|Vega:OTTMUSG00000054985 +66790 Grtp1 MGI:MGI:1914040|Ensembl:ENSMUSG00000038515|Vega:OTTMUSG00000060872 +66793 Efcab1 MGI:MGI:1914043|Ensembl:ENSMUSG00000068617 +66795 Atg10 MGI:MGI:1914045|Ensembl:ENSMUSG00000021619 +66797 Cntnap2 MGI:MGI:1914047|Ensembl:ENSMUSG00000039419|Vega:OTTMUSG00000022414 +66799 Ube2w MGI:MGI:1914049|Ensembl:ENSMUSG00000025939|Vega:OTTMUSG00000029683 +66801 Prkrip1 MGI:MGI:1914051|Ensembl:ENSMUSG00000039737|Vega:OTTMUSG00000025448 +66804 8430408J09Rik MGI:MGI:1914054 +66805 Tspan1 MGI:MGI:1914055|Ensembl:ENSMUSG00000028699|Vega:OTTMUSG00000009310 +66808 9030624G23Rik MGI:MGI:1914058|Ensembl:ENSMUSG00000073158 +66809 Krt20 MGI:MGI:1914059|Ensembl:ENSMUSG00000035775|Vega:OTTMUSG00000004985 +66810 Rbm22 MGI:MGI:1914060|Ensembl:ENSMUSG00000024604|Vega:OTTMUSG00000029033 +66811 Duoxa2 MGI:MGI:1914061|Ensembl:ENSMUSG00000027225|Vega:OTTMUSG00000015566 +66812 Ppcdc MGI:MGI:1914062|Ensembl:ENSMUSG00000063849|Vega:OTTMUSG00000063143 +66813 Bcl2l14 MGI:MGI:1914063|Ensembl:ENSMUSG00000030200|Vega:OTTMUSG00000024227 +66815 Mcub MGI:MGI:1914065|Ensembl:ENSMUSG00000027994|Vega:OTTMUSG00000026525 +66816 Thap2 MGI:MGI:1914066|Ensembl:ENSMUSG00000020137 +66817 Tmem170 MGI:MGI:106426|Ensembl:ENSMUSG00000031953|Vega:OTTMUSG00000061804 +66818 Smim7 MGI:MGI:1914068|Ensembl:ENSMUSG00000044600|Vega:OTTMUSG00000036577 +66821 Bcs1l MGI:MGI:1914071|Ensembl:ENSMUSG00000026172|Vega:OTTMUSG00000021745 +66822 Fbxo25 MGI:MGI:1914072|Ensembl:ENSMUSG00000038365|Vega:OTTMUSG00000060792 +66824 Pycard MGI:MGI:1931465|Ensembl:ENSMUSG00000030793|Vega:OTTMUSG00000025367 +66825 Rnf186 MGI:MGI:1914075|Ensembl:ENSMUSG00000070661|Vega:OTTMUSG00000009898 +66826 Taz MGI:MGI:109626|Ensembl:ENSMUSG00000009995|Vega:OTTMUSG00000017668 +66827 Ttc1 MGI:MGI:1914077|Ensembl:ENSMUSG00000041278|Vega:OTTMUSG00000005463 +66829 Lrrc75aos2 MGI:MGI:1914079 +66830 Nacc1 MGI:MGI:1914080|Ensembl:ENSMUSG00000001910 +66832 Rsph3a MGI:MGI:1914082|Ensembl:ENSMUSG00000073471 +66833 4930518C04Rik MGI:MGI:1914083 +66834 Acot13 MGI:MGI:1914084|Ensembl:ENSMUSG00000006717|Vega:OTTMUSG00000000608 +66835 Snord123 MGI:MGI:5297223|Ensembl:ENSMUSG00000089317 +66836 Tmem223 MGI:MGI:1914086|Ensembl:ENSMUSG00000010097 +66838 0610009L18Rik MGI:MGI:1914088|Ensembl:ENSMUSG00000043644|Vega:OTTMUSG00000004146 +66839 0610009O20Rik MGI:MGI:1914089|Ensembl:ENSMUSG00000024442 +66840 Wdr45b MGI:MGI:1914090|Ensembl:ENSMUSG00000025173|Vega:OTTMUSG00000004473 +66841 Etfdh MGI:MGI:106100|Ensembl:ENSMUSG00000027809|Vega:OTTMUSG00000029395 +66844 Ormdl2 MGI:MGI:1914094|Ensembl:ENSMUSG00000025353 +66845 Mrpl33 MGI:MGI:2137225|Ensembl:ENSMUSG00000106918|Vega:OTTMUSG00000028300 +66847 Hint3 MGI:MGI:1914097|Ensembl:ENSMUSG00000019791|Vega:OTTMUSG00000028055 +66848 Fuca2 MGI:MGI:1914098|Ensembl:ENSMUSG00000019810|Vega:OTTMUSG00000026398 +66849 Ppp1r2 MGI:MGI:1914099|Ensembl:ENSMUSG00000047714|Vega:OTTMUSG00000023915 +66853 Pnpla2 MGI:MGI:1914103|Ensembl:ENSMUSG00000025509|Vega:OTTMUSG00000035378 +66854 Trim35 MGI:MGI:1914104|Ensembl:ENSMUSG00000022043|Vega:OTTMUSG00000027825 +66855 Tcf25 MGI:MGI:1914105|Ensembl:ENSMUSG00000001472|Vega:OTTMUSG00000061965 +66857 Plbd1 MGI:MGI:1914107|Ensembl:ENSMUSG00000030214|Vega:OTTMUSG00000024332 +66859 Slc16a9 MGI:MGI:1914109|Ensembl:ENSMUSG00000037762|Vega:OTTMUSG00000027942 +66860 Tanc1 MGI:MGI:1914110|Ensembl:ENSMUSG00000035168|Vega:OTTMUSG00000012709 +66861 Dnajc10 MGI:MGI:1914111|Ensembl:ENSMUSG00000027006|Vega:OTTMUSG00000013339 +66863 Lztr1 MGI:MGI:1914113|Ensembl:ENSMUSG00000022761|Vega:OTTMUSG00000025194 +66864 Clec14a MGI:MGI:1914114|Ensembl:ENSMUSG00000045930 +66865 Pmpca MGI:MGI:1918568|Ensembl:ENSMUSG00000026926|Vega:OTTMUSG00000012769 +66866 Nhlrc2 MGI:MGI:1914116|Ensembl:ENSMUSG00000025078 +66867 Hmg20a MGI:MGI:1914117|Ensembl:ENSMUSG00000032329|Vega:OTTMUSG00000063120 +66868 Mfsd1 MGI:MGI:1914118|Ensembl:ENSMUSG00000027775|Vega:OTTMUSG00000051286 +66869 Zfp869 MGI:MGI:1914119|Ensembl:ENSMUSG00000054648 +66870 Serbp1 MGI:MGI:1914120|Ensembl:ENSMUSG00000036371|Vega:OTTMUSG00000057415 +66871 Cpne8 MGI:MGI:1914121|Ensembl:ENSMUSG00000052560|Vega:OTTMUSG00000024751 +66873 Tril MGI:MGI:1914123|Ensembl:ENSMUSG00000043496|Vega:OTTMUSG00000033509 +66874 Ncbp3 MGI:MGI:1914124|Ensembl:ENSMUSG00000020783|Vega:OTTMUSG00000006118 +66875 Swt1 MGI:MGI:1914125|Ensembl:ENSMUSG00000052748|Vega:OTTMUSG00000033903 +66877 Crnkl1 MGI:MGI:1914127|Ensembl:ENSMUSG00000001767|Vega:OTTMUSG00000004058 +66878 Riok3 MGI:MGI:1914128|Ensembl:ENSMUSG00000024404 +66880 Rsrc1 MGI:MGI:1914130|Ensembl:ENSMUSG00000034544|Vega:OTTMUSG00000035041 +66881 Pcyox1 MGI:MGI:1914131|Ensembl:ENSMUSG00000029998|Vega:OTTMUSG00000023410 +66882 Bzw1 MGI:MGI:1914132|Ensembl:ENSMUSG00000051223|Vega:OTTMUSG00000047207 +66884 Appbp2 MGI:MGI:1914134|Ensembl:ENSMUSG00000018481|Vega:OTTMUSG00000001027 +66885 Acadsb MGI:MGI:1914135|Ensembl:ENSMUSG00000030861|Vega:OTTMUSG00000026268 +66887 Lonp2 MGI:MGI:1914137|Ensembl:ENSMUSG00000047866|Vega:OTTMUSG00000031421 +66889 Rnf128 MGI:MGI:1914139|Ensembl:ENSMUSG00000031438|Vega:OTTMUSG00000018735 +66890 Lman2 MGI:MGI:1914140|Ensembl:ENSMUSG00000021484 +66892 Eif4e3 MGI:MGI:1914142|Ensembl:ENSMUSG00000093661|Vega:OTTMUSG00000042259 +66894 Wwp2 MGI:MGI:1914144|Ensembl:ENSMUSG00000031930|Vega:OTTMUSG00000061861 +66895 Pxdc1 MGI:MGI:1914145|Ensembl:ENSMUSG00000021411|Vega:OTTMUSG00000027717 +66897 Naa16 MGI:MGI:1914147|Ensembl:ENSMUSG00000022020|Vega:OTTMUSG00000035187 +66898 Baiap2l1 MGI:MGI:1914148|Ensembl:ENSMUSG00000038859|Vega:OTTMUSG00000025584 +66899 Fip1l1 MGI:MGI:1914149|Ensembl:ENSMUSG00000029227|Vega:OTTMUSG00000028601 +66901 Proz MGI:MGI:1860488|Ensembl:ENSMUSG00000031445|Vega:OTTMUSG00000060863 +66902 Mtap MGI:MGI:1914152|Ensembl:ENSMUSG00000062937|Vega:OTTMUSG00000007694 +66904 Pccb MGI:MGI:1914154|Ensembl:ENSMUSG00000032527|Vega:OTTMUSG00000033484 +66905 Plin3 MGI:MGI:1914155|Ensembl:ENSMUSG00000024197 +66910 Tmem107 MGI:MGI:1914160|Ensembl:ENSMUSG00000020895|Vega:OTTMUSG00000005959 +66911 Nudt16l1 MGI:MGI:1914161|Ensembl:ENSMUSG00000022516 +66912 Bzw2 MGI:MGI:1914162|Ensembl:ENSMUSG00000020547 +66913 Kdelr2 MGI:MGI:1914163|Ensembl:ENSMUSG00000079111|Vega:OTTMUSG00000054914 +66914 Vps28 MGI:MGI:1914164|Ensembl:ENSMUSG00000059323 +66915 Cops9 MGI:MGI:1914165|Ensembl:ENSMUSG00000073616|Vega:OTTMUSG00000022121 +66916 Ndufb7 MGI:MGI:1914166|Ensembl:ENSMUSG00000033938|Vega:OTTMUSG00000032846 +66917 Chordc1 MGI:MGI:1914167|Ensembl:ENSMUSG00000001774|Vega:OTTMUSG00000062558 +66921 Prpf38b MGI:MGI:1914171|Ensembl:ENSMUSG00000027881|Vega:OTTMUSG00000007286 +66922 Rras2 MGI:MGI:1914172|Ensembl:ENSMUSG00000055723|Vega:OTTMUSG00000060367 +66923 Pbrm1 MGI:MGI:1923998|Ensembl:ENSMUSG00000042323|Vega:OTTMUSG00000023870 +66925 Sdhd MGI:MGI:1914175|Ensembl:ENSMUSG00000000171|Vega:OTTMUSG00000063072 +66926 Trmt6 MGI:MGI:1914176|Ensembl:ENSMUSG00000037376|Vega:OTTMUSG00000015648 +66928 Tmem261 MGI:MGI:1914178|Ensembl:ENSMUSG00000028398|Vega:OTTMUSG00000000360 +66929 Asf1b MGI:MGI:1914179|Ensembl:ENSMUSG00000005470|Vega:OTTMUSG00000017288 +66930 Fank1 MGI:MGI:1914180|Ensembl:ENSMUSG00000053111|Vega:OTTMUSG00000022584 +66931 1700010I14Rik MGI:MGI:1914181|Ensembl:ENSMUSG00000023873|Vega:OTTMUSG00000028081 +66932 Rexo1 MGI:MGI:1914182|Ensembl:ENSMUSG00000047417|Vega:OTTMUSG00000043566 +66933 1700025L06Rik MGI:MGI:1914183 +66934 Dsn1 MGI:MGI:1914184|Ensembl:ENSMUSG00000027635|Vega:OTTMUSG00000016163 +66935 Cir1 MGI:MGI:1914185|Ensembl:ENSMUSG00000041777|Vega:OTTMUSG00000013426 +66938 Sh3d21 MGI:MGI:1914188|Ensembl:ENSMUSG00000073758|Vega:OTTMUSG00000009352 +66939 Aagab MGI:MGI:1914189|Ensembl:ENSMUSG00000037257|Vega:OTTMUSG00000062586 +66940 Shisa5 MGI:MGI:1915044|Ensembl:ENSMUSG00000025647|Vega:OTTMUSG00000031613 +66942 Ddx18 MGI:MGI:1914192|Ensembl:ENSMUSG00000001674|Vega:OTTMUSG00000019928 +66943 Pqlc1 MGI:MGI:1914193|Ensembl:ENSMUSG00000034006|Vega:OTTMUSG00000033138 +66945 Sdha MGI:MGI:1914195|Ensembl:ENSMUSG00000021577|Vega:OTTMUSG00000030724 +66948 Acad8 MGI:MGI:1914198|Ensembl:ENSMUSG00000031969|Vega:OTTMUSG00000029982 +66949 Trim59 MGI:MGI:1914199|Ensembl:ENSMUSG00000034317|Vega:OTTMUSG00000024493 +66950 Tmem206 MGI:MGI:1914200|Ensembl:ENSMUSG00000026627|Vega:OTTMUSG00000029581 +66952 2310030G06Rik MGI:MGI:1914202|Ensembl:ENSMUSG00000032062|Vega:OTTMUSG00000063074 +66953 Cdca7 MGI:MGI:1914203|Ensembl:ENSMUSG00000055612|Vega:OTTMUSG00000013166 +66957 Serpinb11 MGI:MGI:1914207|Ensembl:ENSMUSG00000026327|Vega:OTTMUSG00000020991 +66958 Tmx2 MGI:MGI:1914208|Ensembl:ENSMUSG00000050043|Vega:OTTMUSG00000013511 +66959 Dusp26 MGI:MGI:1914209|Ensembl:ENSMUSG00000039661|Vega:OTTMUSG00000027144 +66960 Mindy3 MGI:MGI:1914210|Ensembl:ENSMUSG00000026767|Vega:OTTMUSG00000011370 +66961 Neat1 MGI:MGI:1914211|Ensembl:ENSMUSG00000092274 +66962 Swsap1 MGI:MGI:1914212|Ensembl:ENSMUSG00000051238|Vega:OTTMUSG00000062322 +66964 Golt1b MGI:MGI:1914214|Ensembl:ENSMUSG00000030245|Vega:OTTMUSG00000022476 +66965 Ctu2 MGI:MGI:1914215|Ensembl:ENSMUSG00000049482|Vega:OTTMUSG00000022400 +66966 Trit1 MGI:MGI:1914216|Ensembl:ENSMUSG00000028653|Vega:OTTMUSG00000008938 +66967 Edem3 MGI:MGI:1914217|Ensembl:ENSMUSG00000043019|Vega:OTTMUSG00000049645 +66968 Plin5 MGI:MGI:1914218|Ensembl:ENSMUSG00000011305|Vega:OTTMUSG00000035787 +66970 Ssbp2 MGI:MGI:1914220|Ensembl:ENSMUSG00000003992|Vega:OTTMUSG00000024516 +66971 Cdk5rap1 MGI:MGI:1914221|Ensembl:ENSMUSG00000027487|Vega:OTTMUSG00000015918 +66972 Slc25a23 MGI:MGI:1914222|Ensembl:ENSMUSG00000046329|Vega:OTTMUSG00000035805 +66973 Mrps18b MGI:MGI:1914223|Ensembl:ENSMUSG00000024436|Vega:OTTMUSG00000037410 +66975 Trappc13 MGI:MGI:1914225|Ensembl:ENSMUSG00000021711|Vega:OTTMUSG00000032909 +66977 Nuf2 MGI:MGI:1914227|Ensembl:ENSMUSG00000026683|Vega:OTTMUSG00000049910 +66978 Luc7l MGI:MGI:1914228|Ensembl:ENSMUSG00000024188|Vega:OTTMUSG00000021926 +66979 Pole4 MGI:MGI:1914229|Ensembl:ENSMUSG00000030042|Vega:OTTMUSG00000023086 +66980 Zdhhc6 MGI:MGI:1914230|Ensembl:ENSMUSG00000024982 +66983 Zfp830 MGI:MGI:1914233|Ensembl:ENSMUSG00000046010|Vega:OTTMUSG00000000903 +66985 Rassf7 MGI:MGI:1914235|Ensembl:ENSMUSG00000038618|Vega:OTTMUSG00000023203 +66988 Lap3 MGI:MGI:1914238|Ensembl:ENSMUSG00000039682|Vega:OTTMUSG00000027770 +66989 Kctd20 MGI:MGI:1914239|Ensembl:ENSMUSG00000005936|Vega:OTTMUSG00000031640 +66990 Tmem134 MGI:MGI:1914240 +66991 Khdc3 MGI:MGI:1914241|Ensembl:ENSMUSG00000092622|Vega:OTTMUSG00000037515 +66993 Smarcd3 MGI:MGI:1914243|Ensembl:ENSMUSG00000028949|Vega:OTTMUSG00000030539 +66994 Cep19 MGI:MGI:1914244|Ensembl:ENSMUSG00000035790|Vega:OTTMUSG00000025796 +66995 Zcchc18 MGI:MGI:1914245|Ensembl:ENSMUSG00000031428|Vega:OTTMUSG00000018826 +66996 Ceacam11 MGI:MGI:1914246|Ensembl:ENSMUSG00000030368|Vega:OTTMUSG00000016942 +66997 Psmd12 MGI:MGI:1914247|Ensembl:ENSMUSG00000020720|Vega:OTTMUSG00000003659 +66998 Psmd5 MGI:MGI:1914248|Ensembl:ENSMUSG00000026869|Vega:OTTMUSG00000012023 +66999 Med28 MGI:MGI:1914249|Ensembl:ENSMUSG00000015804|Vega:OTTMUSG00000027798 +67000 Prl3a1 MGI:MGI:1914250|Ensembl:ENSMUSG00000038883|Vega:OTTMUSG00000000632 +67003 Uqcrc2 MGI:MGI:1914253|Ensembl:ENSMUSG00000030884|Vega:OTTMUSG00000025574 +67005 Polr3k MGI:MGI:1914255|Ensembl:ENSMUSG00000038628|Vega:OTTMUSG00000016835 +67006 Cisd2 MGI:MGI:1914256|Ensembl:ENSMUSG00000028165|Vega:OTTMUSG00000029490 +67008 Yae1d1 MGI:MGI:1914258|Ensembl:ENSMUSG00000075054 +67009 Ttc23 MGI:MGI:1914259|Ensembl:ENSMUSG00000030555|Vega:OTTMUSG00000024992 +67010 Rbm7 MGI:MGI:1914260|Ensembl:ENSMUSG00000042396|Vega:OTTMUSG00000063008 +67011 Mettl6 MGI:MGI:1914261|Ensembl:ENSMUSG00000021891 +67013 Oma1 MGI:MGI:1914263|Ensembl:ENSMUSG00000035069|Vega:OTTMUSG00000008073 +67014 Riox2 MGI:MGI:1914264|Ensembl:ENSMUSG00000022724|Vega:OTTMUSG00000027065 +67015 Ccdc91 MGI:MGI:1914265|Ensembl:ENSMUSG00000030301|Vega:OTTMUSG00000026069 +67016 Tbc1d2b MGI:MGI:1914266|Ensembl:ENSMUSG00000037410|Vega:OTTMUSG00000031688 +67017 Fam210b MGI:MGI:1914267|Ensembl:ENSMUSG00000027495|Vega:OTTMUSG00000016151 +67019 Actr6 MGI:MGI:1914269|Ensembl:ENSMUSG00000019948 +67020 Tmem88 MGI:MGI:1914270|Ensembl:ENSMUSG00000045377|Vega:OTTMUSG00000005978 +67023 Use1 MGI:MGI:1914273|Ensembl:ENSMUSG00000002395|Vega:OTTMUSG00000022213 +67025 Rpl11 MGI:MGI:1914275|Ensembl:ENSMUSG00000059291|Vega:OTTMUSG00000009855 +67026 Thap4 MGI:MGI:1914276|Ensembl:ENSMUSG00000026279|Vega:OTTMUSG00000048661 +67027 Mkrn2 MGI:MGI:1914277|Ensembl:ENSMUSG00000000439|Vega:OTTMUSG00000056677 +67028 2610002M06Rik MGI:MGI:1914278|Ensembl:ENSMUSG00000031242|Vega:OTTMUSG00000018257 +67030 Fancl MGI:MGI:1914280|Ensembl:ENSMUSG00000004018|Vega:OTTMUSG00000008088 +67031 Upf3a MGI:MGI:1914281|Ensembl:ENSMUSG00000038398|Vega:OTTMUSG00000060787 +67035 Dnajb4 MGI:MGI:1914285|Ensembl:ENSMUSG00000028035|Vega:OTTMUSG00000032864 +67036 Mrpl45 MGI:MGI:1914286|Ensembl:ENSMUSG00000018882|Vega:OTTMUSG00000002519 +67037 Pmf1 MGI:MGI:1914287|Ensembl:ENSMUSG00000028066|Vega:OTTMUSG00000052145 +67038 2010109I03Rik MGI:MGI:1914288|Ensembl:ENSMUSG00000063522|Vega:OTTMUSG00000045123 +67039 Rbm25 MGI:MGI:1914289|Ensembl:ENSMUSG00000010608|Vega:OTTMUSG00000043541 +67040 Ddx17 MGI:MGI:1914290|Ensembl:ENSMUSG00000055065 +67041 Oxct1 MGI:MGI:1914291|Ensembl:ENSMUSG00000022186|Vega:OTTMUSG00000024748 +67042 Ift27 MGI:MGI:1914292|Ensembl:ENSMUSG00000016637 +67043 Syap1 MGI:MGI:1914293|Ensembl:ENSMUSG00000031357|Vega:OTTMUSG00000019495 +67044 Higd2a MGI:MGI:1914294|Ensembl:ENSMUSG00000025868|Vega:OTTMUSG00000032685 +67045 Riok2 MGI:MGI:1914295|Ensembl:ENSMUSG00000023852 +67046 Tbc1d7 MGI:MGI:1914296|Ensembl:ENSMUSG00000021368 +67048 Vma21 MGI:MGI:1914298|Ensembl:ENSMUSG00000073131|Vega:OTTMUSG00000017818 +67049 Pus3 MGI:MGI:1914299|Ensembl:ENSMUSG00000032103|Vega:OTTMUSG00000030730 +67050 Nkap MGI:MGI:1914300|Ensembl:ENSMUSG00000016409|Vega:OTTMUSG00000017125 +67052 Ndc80 MGI:MGI:1914302|Ensembl:ENSMUSG00000024056 +67053 Rpp14 MGI:MGI:1914303|Ensembl:ENSMUSG00000023156|Vega:OTTMUSG00000042352 +67054 Paics MGI:MGI:1914304|Ensembl:ENSMUSG00000029247|Vega:OTTMUSG00000026550 +67057 Yaf2 MGI:MGI:1914307|Ensembl:ENSMUSG00000022634|Vega:OTTMUSG00000017284 +67058 2810428J06Rik MGI:MGI:1914308 +67059 Ola1 MGI:MGI:1914309|Ensembl:ENSMUSG00000027108|Vega:OTTMUSG00000013275 +67062 Slc25a53 MGI:MGI:1914312|Ensembl:ENSMUSG00000044348|Vega:OTTMUSG00000018823 +67063 Tmem246 MGI:MGI:1914313|Ensembl:ENSMUSG00000039611|Vega:OTTMUSG00000008319 +67064 Chmp1b MGI:MGI:1914314|Ensembl:ENSMUSG00000109901|Vega:OTTMUSG00000060244 +67065 Polr3d MGI:MGI:1914315|Ensembl:ENSMUSG00000000776 +67067 Romo1 MGI:MGI:1914317|Ensembl:ENSMUSG00000067847|Vega:OTTMUSG00000016121 +67068 Dynlrb1 MGI:MGI:1914318|Ensembl:ENSMUSG00000047459|Vega:OTTMUSG00000016009 +67070 Lsm14a MGI:MGI:1914320|Ensembl:ENSMUSG00000066568|Vega:OTTMUSG00000008387 +67071 Rps6ka6 MGI:MGI:1914321|Ensembl:ENSMUSG00000025665|Vega:OTTMUSG00000018383 +67072 Cdc37l1 MGI:MGI:1914322|Ensembl:ENSMUSG00000024780 +67073 Pi4k2b MGI:MGI:1914323|Ensembl:ENSMUSG00000029186|Vega:OTTMUSG00000023351 +67074 Mon2 MGI:MGI:1914324|Ensembl:ENSMUSG00000034602 +67075 Magt1 MGI:MGI:1914325|Ensembl:ENSMUSG00000031232|Vega:OTTMUSG00000018276 +67077 Catsperz MGI:MGI:1914327|Ensembl:ENSMUSG00000050623 +67078 Pgp MGI:MGI:1914328|Ensembl:ENSMUSG00000043445 +67080 1700019D03Rik MGI:MGI:1914330|Ensembl:ENSMUSG00000043629|Vega:OTTMUSG00000021472 +67081 1700025F24Rik MGI:MGI:1914331|Ensembl:ENSMUSG00000100558 +67082 1700011H14Rik MGI:MGI:1914332|Ensembl:ENSMUSG00000021850|Vega:OTTMUSG00000027957 +67084 Ceacam14 MGI:MGI:1914334|Ensembl:ENSMUSG00000023185|Vega:OTTMUSG00000016964 +67085 1700024G13Rik MGI:MGI:1914335|Ensembl:ENSMUSG00000072473 +67086 1700020N18Rik MGI:MGI:1914336|Ensembl:ENSMUSG00000100253 +67087 Ctnnbip1 MGI:MGI:1915756|Ensembl:ENSMUSG00000028988|Vega:OTTMUSG00000010278 +67088 Cand2 MGI:MGI:1914338|Ensembl:ENSMUSG00000030319|Vega:OTTMUSG00000023297 +67089 Psmc6 MGI:MGI:1914339|Ensembl:ENSMUSG00000021832 +67091 Trappc6a MGI:MGI:1914341|Ensembl:ENSMUSG00000002043|Vega:OTTMUSG00000022255 +67092 Gatm MGI:MGI:1914342|Ensembl:ENSMUSG00000027199|Vega:OTTMUSG00000015672 +67095 Trak1 MGI:MGI:1914345|Ensembl:ENSMUSG00000032536|Vega:OTTMUSG00000060874 +67096 Mmachc MGI:MGI:1914346|Ensembl:ENSMUSG00000028690|Vega:OTTMUSG00000009547 +67097 Rps10 MGI:MGI:1914347|Ensembl:ENSMUSG00000052146|Vega:OTTMUSG00000021337 +67099 Mettl21a MGI:MGI:1914349|Ensembl:ENSMUSG00000025956|Vega:OTTMUSG00000026623 +67101 2310039H08Rik MGI:MGI:1914351|Ensembl:ENSMUSG00000062619 +67102 D16Ertd472e MGI:MGI:1196400|Ensembl:ENSMUSG00000022864|Vega:OTTMUSG00000019868 +67103 Ptgr1 MGI:MGI:1914353|Ensembl:ENSMUSG00000028378|Vega:OTTMUSG00000007624 +67105 Timm21 MGI:MGI:1920595|Ensembl:ENSMUSG00000024645 +67106 Zbtb8os MGI:MGI:1914356|Ensembl:ENSMUSG00000057572|Vega:OTTMUSG00000009628 +67107 Gm9517 MGI:MGI:3779430 +67109 Zfp787 MGI:MGI:1914359|Ensembl:ENSMUSG00000046792|Vega:OTTMUSG00000060037 +67111 Naaa MGI:MGI:1914361|Ensembl:ENSMUSG00000029413|Vega:OTTMUSG00000024987 +67112 Fgf22 MGI:MGI:1914362|Ensembl:ENSMUSG00000020327 +67115 Rpl14 MGI:MGI:1914365|Ensembl:ENSMUSG00000025794|Vega:OTTMUSG00000062595 +67116 Cuedc2 MGI:MGI:1914366|Ensembl:ENSMUSG00000036748 +67117 Dynlt3 MGI:MGI:1914367|Ensembl:ENSMUSG00000031176|Vega:OTTMUSG00000016890 +67118 Bfar MGI:MGI:1914368|Ensembl:ENSMUSG00000022684|Ensembl:ENSMUSG00000079737|Vega:OTTMUSG00000028684|Vega:OTTMUSG00000028685 +67119 Ccdc159 MGI:MGI:1914369|Ensembl:ENSMUSG00000006241|Vega:OTTMUSG00000062320 +67120 Ttc14 MGI:MGI:1914370|Ensembl:ENSMUSG00000027677|Vega:OTTMUSG00000026490 +67121 Mastl MGI:MGI:1914371|Ensembl:ENSMUSG00000026779|Vega:OTTMUSG00000011632 +67122 Nrarp MGI:MGI:1914372|Ensembl:ENSMUSG00000078202|Vega:OTTMUSG00000011778 +67123 Ubap1 MGI:MGI:2149543|Ensembl:ENSMUSG00000028437|Vega:OTTMUSG00000006663 +67125 Tspan31 MGI:MGI:1914375|Ensembl:ENSMUSG00000006736 +67126 Atp5e MGI:MGI:1855697|Ensembl:ENSMUSG00000016252|Vega:OTTMUSG00000016513 +67127 Lce1a1 MGI:MGI:1914377|Ensembl:ENSMUSG00000057609|Vega:OTTMUSG00000051846 +67128 Ube2g1 MGI:MGI:1914378|Ensembl:ENSMUSG00000020794|Vega:OTTMUSG00000006111 +67130 Ndufa6 MGI:MGI:1914380|Ensembl:ENSMUSG00000022450 +67131 Acbd4 MGI:MGI:1914381|Ensembl:ENSMUSG00000056938|Vega:OTTMUSG00000003297 +67133 Gp2 MGI:MGI:1914383|Ensembl:ENSMUSG00000030954|Vega:OTTMUSG00000059101 +67134 Nop56 MGI:MGI:1914384|Ensembl:ENSMUSG00000027405|Vega:OTTMUSG00000015495 +67135 Bpifa5 MGI:MGI:1914385|Ensembl:ENSMUSG00000027484|Vega:OTTMUSG00000016853 +67136 Kbtbd4 MGI:MGI:1914386|Ensembl:ENSMUSG00000005505|Vega:OTTMUSG00000014319 +67138 Herc6 MGI:MGI:1914388|Ensembl:ENSMUSG00000029798|Vega:OTTMUSG00000057867 +67139 Mis12 MGI:MGI:1914389|Ensembl:ENSMUSG00000040599|Vega:OTTMUSG00000006078 +67141 Fbxo5 MGI:MGI:1914391|Ensembl:ENSMUSG00000019773|Vega:OTTMUSG00000022756 +67142 2510019K15Rik MGI:MGI:1914392 +67143 Ikzf5 MGI:MGI:1914393|Ensembl:ENSMUSG00000040167|Vega:OTTMUSG00000026280 +67144 Lrrc40 MGI:MGI:1914394|Ensembl:ENSMUSG00000063052|Vega:OTTMUSG00000031933 +67145 Tomm34 MGI:MGI:1914395|Ensembl:ENSMUSG00000018322|Vega:OTTMUSG00000016136 +67148 Fam103a1 MGI:MGI:1914398|Ensembl:ENSMUSG00000038646|Vega:OTTMUSG00000028999 +67149 Nkain1 MGI:MGI:1914399|Ensembl:ENSMUSG00000078532|Vega:OTTMUSG00000042996 +67150 Rnf141 MGI:MGI:1914400|Ensembl:ENSMUSG00000030788|Vega:OTTMUSG00000042213 +67151 Psmd9 MGI:MGI:1914401|Ensembl:ENSMUSG00000029440|Vega:OTTMUSG00000023710 +67153 Rnaseh2b MGI:MGI:1914403|Ensembl:ENSMUSG00000021932|Vega:OTTMUSG00000019771 +67154 Mtdh MGI:MGI:1914404|Ensembl:ENSMUSG00000022255|Vega:OTTMUSG00000036553 +67155 Smarca2 MGI:MGI:99603|Ensembl:ENSMUSG00000024921|Vega:OTTMUSG00000040069 +67157 2610301B20Rik MGI:MGI:1914407|Ensembl:ENSMUSG00000059482|Vega:OTTMUSG00000009187 +67158 Sft2d3 MGI:MGI:1914408|Ensembl:ENSMUSG00000044982 +67160 Eef1g MGI:MGI:1914410|Ensembl:ENSMUSG00000071644|Vega:OTTMUSG00000020426 +67161 Sclt1 MGI:MGI:1914411|Ensembl:ENSMUSG00000059834|Vega:OTTMUSG00000033588 +67163 Ccdc47 MGI:MGI:1914413|Ensembl:ENSMUSG00000078622|Vega:OTTMUSG00000003221 +67164 Lipt2 MGI:MGI:1914414|Ensembl:ENSMUSG00000030725|Vega:OTTMUSG00000025283 +67166 Arl8b MGI:MGI:1914416|Ensembl:ENSMUSG00000030105|Vega:OTTMUSG00000056447 +67168 Lpar6 MGI:MGI:1914418|Ensembl:ENSMUSG00000033446|Vega:OTTMUSG00000036134 +67169 Nradd MGI:MGI:1914419|Ensembl:ENSMUSG00000032491|Vega:OTTMUSG00000051580 +67170 2610306M01Rik MGI:MGI:1914420|Ensembl:ENSMUSG00000100164 +67171 Dram2 MGI:MGI:1914421|Ensembl:ENSMUSG00000027900|Vega:OTTMUSG00000029479 +67177 Cdt1 MGI:MGI:1914427|Ensembl:ENSMUSG00000006585|Vega:OTTMUSG00000061851 +67178 Zmat5 MGI:MGI:1914428|Ensembl:ENSMUSG00000009076|Vega:OTTMUSG00000005068 +67179 Ccdc25 MGI:MGI:1914429|Ensembl:ENSMUSG00000022035 +67180 Yipf5 MGI:MGI:1914430|Ensembl:ENSMUSG00000024487 +67181 Ctdnep1 MGI:MGI:1914431|Ensembl:ENSMUSG00000018559|Vega:OTTMUSG00000006022 +67182 Pdzk1ip1 MGI:MGI:1914432|Ensembl:ENSMUSG00000028716|Vega:OTTMUSG00000008589 +67184 Ndufa13 MGI:MGI:1914434|Ensembl:ENSMUSG00000036199|Ensembl:ENSMUSG00000048967|Vega:OTTMUSG00000033931|Vega:OTTMUSG00000062221 +67186 Rplp2 MGI:MGI:1914436|Ensembl:ENSMUSG00000025508|Vega:OTTMUSG00000024569 +67187 Zmynd19 MGI:MGI:1914437|Ensembl:ENSMUSG00000026974|Vega:OTTMUSG00000011513 +67188 2700046G09Rik MGI:MGI:1914438|Ensembl:ENSMUSG00000097787 +67194 2700038G22Rik MGI:MGI:1914444|Ensembl:ENSMUSG00000097180 +67196 Ube2t MGI:MGI:1914446|Ensembl:ENSMUSG00000026429|Vega:OTTMUSG00000021432 +67197 Zcrb1 MGI:MGI:1914447|Ensembl:ENSMUSG00000022635|Vega:OTTMUSG00000034433 +67198 Spats2l MGI:MGI:1914448|Ensembl:ENSMUSG00000038305|Vega:OTTMUSG00000035161 +67199 Pfdn1 MGI:MGI:1914449|Ensembl:ENSMUSG00000024346 +67200 Ccdc77 MGI:MGI:1914450|Ensembl:ENSMUSG00000030177|Vega:OTTMUSG00000023918 +67201 Glod4 MGI:MGI:1914451|Ensembl:ENSMUSG00000017286|Vega:OTTMUSG00000006228 +67203 Nde1 MGI:MGI:1914453|Ensembl:ENSMUSG00000022678|Vega:OTTMUSG00000027034 +67204 Eif2s2 MGI:MGI:1914454|Ensembl:ENSMUSG00000074656|Vega:OTTMUSG00000015977 +67205 Utp11 MGI:MGI:1914455|Ensembl:ENSMUSG00000028907|Vega:OTTMUSG00000009171 +67207 Lsm1 MGI:MGI:1914457|Ensembl:ENSMUSG00000037296|Vega:OTTMUSG00000060663 +67210 Gatad1 MGI:MGI:1914460|Ensembl:ENSMUSG00000007415|Vega:OTTMUSG00000028536 +67211 Armc10 MGI:MGI:1914461|Ensembl:ENSMUSG00000038525|Vega:OTTMUSG00000025663 +67212 Mrpl55 MGI:MGI:1914462|Ensembl:ENSMUSG00000036860|Vega:OTTMUSG00000005787 +67213 Cmtm6 MGI:MGI:2447165|Ensembl:ENSMUSG00000032434|Vega:OTTMUSG00000062858 +67216 Mboat2 MGI:MGI:1914466|Ensembl:ENSMUSG00000020646 +67217 L3hypdh MGI:MGI:1914467|Ensembl:ENSMUSG00000019718|Vega:OTTMUSG00000027641 +67218 2810038D20Rik MGI:MGI:1914468 +67219 Med18 MGI:MGI:1914469|Ensembl:ENSMUSG00000066042|Vega:OTTMUSG00000009673 +67220 Plekho1 MGI:MGI:1914470|Ensembl:ENSMUSG00000015745|Vega:OTTMUSG00000022186 +67222 Srfbp1 MGI:MGI:1914472|Ensembl:ENSMUSG00000024528 +67223 Rrp15 MGI:MGI:1914473|Ensembl:ENSMUSG00000001305|Vega:OTTMUSG00000034905 +67224 Med29 MGI:MGI:1914474|Ensembl:ENSMUSG00000003444|Vega:OTTMUSG00000023735 +67225 Rnpc3 MGI:MGI:1914475|Ensembl:ENSMUSG00000027981|Vega:OTTMUSG00000022379 +67226 Tmem19 MGI:MGI:1914476|Ensembl:ENSMUSG00000069520 +67228 Dph7 MGI:MGI:1914478|Ensembl:ENSMUSG00000026975|Vega:OTTMUSG00000011563 +67229 Prpf18 MGI:MGI:1914479|Ensembl:ENSMUSG00000039449|Vega:OTTMUSG00000010793 +67230 Zfp329 MGI:MGI:1921283|Ensembl:ENSMUSG00000057894|Vega:OTTMUSG00000022349 +67231 Tbc1d20 MGI:MGI:1914481|Ensembl:ENSMUSG00000027465|Vega:OTTMUSG00000015833 +67234 2810449D17Rik MGI:MGI:1914484 +67235 Zkscan14 MGI:MGI:1914485|Ensembl:ENSMUSG00000029627|Vega:OTTMUSG00000022929 +67236 Cinp MGI:MGI:1914486|Ensembl:ENSMUSG00000021276 +67238 Fam220a MGI:MGI:1914488|Ensembl:ENSMUSG00000083012|Vega:OTTMUSG00000029039 +67239 Rpf2 MGI:MGI:1914489|Ensembl:ENSMUSG00000038510|Vega:OTTMUSG00000043583 +67241 Smc6 MGI:MGI:1914491|Ensembl:ENSMUSG00000020608 +67242 Gemin6 MGI:MGI:1914492|Ensembl:ENSMUSG00000055760|Vega:OTTMUSG00000024347 +67245 Peli1 MGI:MGI:1914495|Ensembl:ENSMUSG00000020134|Vega:OTTMUSG00000005237 +67246 2810474O19Rik MGI:MGI:1914496|Ensembl:ENSMUSG00000032712|Vega:OTTMUSG00000026189 +67247 Marc2 MGI:MGI:1914497|Ensembl:ENSMUSG00000073481|Vega:OTTMUSG00000034883 +67248 Rpl39 MGI:MGI:1914498|Ensembl:ENSMUSG00000079641|Vega:OTTMUSG00000017100 +67249 Tbc1d19 MGI:MGI:1914499|Ensembl:ENSMUSG00000039178|Vega:OTTMUSG00000054962 +67252 Cap2 MGI:MGI:1914502|Ensembl:ENSMUSG00000021373|Vega:OTTMUSG00000029305 +67254 2900011O08Rik MGI:MGI:1914504|Ensembl:ENSMUSG00000044117|Vega:OTTMUSG00000026346 +67255 Zfp422 MGI:MGI:1914505|Ensembl:ENSMUSG00000059878|Vega:OTTMUSG00000021176 +67256 Dlx6os3 MGI:MGI:1914506 +67260 Cers4 MGI:MGI:1914510|Ensembl:ENSMUSG00000008206|Vega:OTTMUSG00000042002 +67261 2900005J15Rik MGI:MGI:1914511|Ensembl:ENSMUSG00000043833 +67263 Zswim6 MGI:MGI:1914513|Ensembl:ENSMUSG00000032846 +67264 Ndufb8 MGI:MGI:1914514|Ensembl:ENSMUSG00000025204|Vega:OTTMUSG00000036225 +67266 Fam69a MGI:MGI:1914516|Ensembl:ENSMUSG00000029270|Vega:OTTMUSG00000028903 +67267 Uqcc2 MGI:MGI:1914517|Ensembl:ENSMUSG00000024208|Vega:OTTMUSG00000031358 +67268 Myl12a MGI:MGI:1914518|Ensembl:ENSMUSG00000024048|Vega:OTTMUSG00000033039 +67269 Agtpbp1 MGI:MGI:2159437|Ensembl:ENSMUSG00000021557|Vega:OTTMUSG00000035354 +67270 Mrpl42 MGI:MGI:1333774|Ensembl:ENSMUSG00000062981 +67272 Cmtm5 MGI:MGI:2447164|Ensembl:ENSMUSG00000040759 +67273 Ndufa10 MGI:MGI:1914523|Ensembl:ENSMUSG00000026260|Vega:OTTMUSG00000021762 +67276 Eri1 MGI:MGI:1914526|Ensembl:ENSMUSG00000031527|Vega:OTTMUSG00000061038 +67277 2900089D17Rik MGI:MGI:1914527 +67278 Pagr1a MGI:MGI:1914528|Ensembl:ENSMUSG00000030680|Ensembl:ENSMUSG00000107068|Vega:OTTMUSG00000033691 +67279 Med31 MGI:MGI:1914529|Ensembl:ENSMUSG00000020801|Vega:OTTMUSG00000006102 +67280 3110009F21Rik MGI:MGI:1914530|Ensembl:ENSMUSG00000113331 +67281 Rpl37 MGI:MGI:1914531|Ensembl:ENSMUSG00000041841 +67282 Washc3 MGI:MGI:1914532|Ensembl:ENSMUSG00000020056|Vega:OTTMUSG00000044399 +67283 Slc25a19 MGI:MGI:1914533|Ensembl:ENSMUSG00000020744|Vega:OTTMUSG00000003476 +67285 Cwc27 MGI:MGI:1914535|Ensembl:ENSMUSG00000021715|Vega:OTTMUSG00000029392 +67286 Ift22 MGI:MGI:1914536|Ensembl:ENSMUSG00000007987|Vega:OTTMUSG00000054403 +67287 Parp6 MGI:MGI:1914537|Ensembl:ENSMUSG00000025237|Vega:OTTMUSG00000063296 +67288 Srek1ip1 MGI:MGI:1914538|Ensembl:ENSMUSG00000021716|Vega:OTTMUSG00000029563 +67289 3110021A11Rik MGI:MGI:1914539 +67290 3110040N11Rik MGI:MGI:1914540|Ensembl:ENSMUSG00000025102|Vega:OTTMUSG00000023339 +67291 Ccdc137 MGI:MGI:1914541|Ensembl:ENSMUSG00000049957|Vega:OTTMUSG00000004186 +67292 Pigc MGI:MGI:1914542|Ensembl:ENSMUSG00000026698|Vega:OTTMUSG00000029439 +67293 3110039M20Rik MGI:MGI:1914543|Ensembl:ENSMUSG00000104861 +67295 Rab3c MGI:MGI:1914545|Ensembl:ENSMUSG00000021700 +67296 Socs4 MGI:MGI:1914546|Ensembl:ENSMUSG00000048379|Vega:OTTMUSG00000027545 +67298 Gprasp1 MGI:MGI:1917418|Ensembl:ENSMUSG00000043384|Vega:OTTMUSG00000018754 +67299 Dock7 MGI:MGI:1914549|Ensembl:ENSMUSG00000028556|Vega:OTTMUSG00000008703 +67300 Cltc MGI:MGI:2388633|Ensembl:ENSMUSG00000047126|Vega:OTTMUSG00000001209 +67302 Zc3h13 MGI:MGI:1914552|Ensembl:ENSMUSG00000022000 +67303 3110045C21Rik MGI:MGI:1914553|Ensembl:ENSMUSG00000097503 +67304 3110070M22Rik MGI:MGI:1914554|Ensembl:ENSMUSG00000074635 +67305 Gpx7 MGI:MGI:1914555|Ensembl:ENSMUSG00000028597|Vega:OTTMUSG00000008245 +67306 Zc2hc1a MGI:MGI:1914556|Ensembl:ENSMUSG00000043542|Vega:OTTMUSG00000051307 +67307 Pbld2 MGI:MGI:1914557|Ensembl:ENSMUSG00000020072|Vega:OTTMUSG00000030876 +67308 Mrpl46 MGI:MGI:1914558|Ensembl:ENSMUSG00000030612|Vega:OTTMUSG00000027303 +67310 Prl8a9 MGI:MGI:1914560|Ensembl:ENSMUSG00000006490|Vega:OTTMUSG00000000641 +67311 Nanp MGI:MGI:1914561|Ensembl:ENSMUSG00000053916|Vega:OTTMUSG00000015785 +67312 1700040B14Rik MGI:MGI:1914562 +67313 5730559C18Rik MGI:MGI:1921579|Ensembl:ENSMUSG00000041605|Vega:OTTMUSG00000029725 +67315 Ceacam12 MGI:MGI:1914565|Ensembl:ENSMUSG00000030366|Vega:OTTMUSG00000016963 +67316 1700037F03Rik MGI:MGI:1914566 +67317 1700022I11Rik MGI:MGI:1914567|Ensembl:ENSMUSG00000028451|Vega:OTTMUSG00000006689 +67319 1700041C23Rik MGI:MGI:1914569|Ensembl:ENSMUSG00000100282 +67320 Iqcf4 MGI:MGI:1914570|Ensembl:ENSMUSG00000041009|Vega:OTTMUSG00000049454 +67321 1700044K03Rik MGI:MGI:1914571|Ensembl:ENSMUSG00000100297 +67323 1700042G07Rik MGI:MGI:1914573|Ensembl:ENSMUSG00000078593|Vega:OTTMUSG00000009307 +67324 1700042D18Rik MGI:MGI:1914574 +67325 1700034G24Rik MGI:MGI:1914575|Ensembl:ENSMUSG00000097962 +67326 1700037H04Rik MGI:MGI:1914576|Ensembl:ENSMUSG00000027327|Vega:OTTMUSG00000015728 +67327 1700031L13Rik MGI:MGI:1914577 +67328 Lyzl1 MGI:MGI:1914578|Ensembl:ENSMUSG00000024233|Vega:OTTMUSG00000028157 +67329 1700018L02Rik MGI:MGI:1914579 +67330 1700047M11Rik MGI:MGI:1914580|Ensembl:ENSMUSG00000100147 +67331 Atp8b3 MGI:MGI:1914581|Ensembl:ENSMUSG00000003341 +67332 Snrpd3 MGI:MGI:1914582|Ensembl:ENSMUSG00000020180|Vega:OTTMUSG00000046606 +67333 Stk35 MGI:MGI:1914583|Ensembl:ENSMUSG00000037885|Vega:OTTMUSG00000015500 +67334 Hypm MGI:MGI:1914584|Ensembl:ENSMUSG00000040456|Vega:OTTMUSG00000017463 +67335 1700060O08Rik MGI:MGI:1914585 +67336 1700054K19Rik MGI:MGI:1914586|Ensembl:ENSMUSG00000100219 +67337 Cstf1 MGI:MGI:1914587|Ensembl:ENSMUSG00000027498|Vega:OTTMUSG00000016157 +67338 Rffl MGI:MGI:1914588|Ensembl:ENSMUSG00000020696|Vega:OTTMUSG00000000906 +67339 1700066J03Rik MGI:MGI:1914589 +67340 1700052I22Rik MGI:MGI:1914590|Ensembl:ENSMUSG00000101912 +67341 Ascl4 MGI:MGI:1914591|Ensembl:ENSMUSG00000085111|Vega:OTTMUSG00000028678 +67342 Kcnmb4os1 MGI:MGI:1914592|Ensembl:ENSMUSG00000020164 +67343 Tex43 MGI:MGI:1914593|Ensembl:ENSMUSG00000032900|Vega:OTTMUSG00000028213 +67344 Tctex1d1 MGI:MGI:1914594|Ensembl:ENSMUSG00000028523|Vega:OTTMUSG00000008071 +67345 Herc4 MGI:MGI:1914595|Ensembl:ENSMUSG00000020064 +67348 1700083H02Rik MGI:MGI:1914598|Ensembl:ENSMUSG00000100668 +67349 1700086P04Rik MGI:MGI:1914599|Ensembl:ENSMUSG00000085085 +67350 1700084E18Rik MGI:MGI:1914600 +67351 Tmem132cos MGI:MGI:1914601|Ensembl:ENSMUSG00000087104 +67352 1700093E11Rik MGI:MGI:1914602 +67355 1700109G14Rik MGI:MGI:1914605|Ensembl:ENSMUSG00000101505 +67356 Tmco5 MGI:MGI:1914606|Ensembl:ENSMUSG00000027355|Vega:OTTMUSG00000015250 +67357 1700092C02Rik MGI:MGI:1914607|Ensembl:ENSMUSG00000086781 +67358 1700093K21Rik MGI:MGI:1914608|Ensembl:ENSMUSG00000020286|Vega:OTTMUSG00000005280 +67360 1700095B10Rik MGI:MGI:1914610|Ensembl:ENSMUSG00000098230 +67364 1700121C10Rik MGI:MGI:1914614 +67365 Pudp MGI:MGI:1914615|Ensembl:ENSMUSG00000048875 +67366 Tmed11 MGI:MGI:1914616|Ensembl:ENSMUSG00000004821|Vega:OTTMUSG00000026764 +67367 Paxbp1 MGI:MGI:1914617|Ensembl:ENSMUSG00000022974|Vega:OTTMUSG00000016279 +67369 Qpctl MGI:MGI:1914619|Ensembl:ENSMUSG00000030407|Vega:OTTMUSG00000058595 +67370 Zfp606 MGI:MGI:1914620|Ensembl:ENSMUSG00000030386|Vega:OTTMUSG00000029122 +67371 Gtf3c6 MGI:MGI:1914621|Ensembl:ENSMUSG00000019837|Vega:OTTMUSG00000063448 +67373 2210010C04Rik MGI:MGI:1914623|Ensembl:ENSMUSG00000029882|Vega:OTTMUSG00000026905 +67374 Jam2 MGI:MGI:1933820|Ensembl:ENSMUSG00000053062|Vega:OTTMUSG00000025168 +67375 Qprt MGI:MGI:1914625|Ensembl:ENSMUSG00000030674|Vega:OTTMUSG00000029412 +67378 Bbs2 MGI:MGI:2135267|Ensembl:ENSMUSG00000031755|Vega:OTTMUSG00000036712 +67379 Dedd2 MGI:MGI:1914629|Ensembl:ENSMUSG00000054499|Vega:OTTMUSG00000058243 +67381 Med4 MGI:MGI:1914631|Ensembl:ENSMUSG00000022109 +67382 Brd3 MGI:MGI:1914632|Ensembl:ENSMUSG00000026918|Vega:OTTMUSG00000012035 +67383 Carnmt1 MGI:MGI:1914633|Ensembl:ENSMUSG00000024726 +67384 Bag4 MGI:MGI:1914634|Ensembl:ENSMUSG00000037316|Vega:OTTMUSG00000060659 +67387 Unc50 MGI:MGI:1914637|Ensembl:ENSMUSG00000026111|Vega:OTTMUSG00000021774 +67388 1110008F13Rik MGI:MGI:1914638|Ensembl:ENSMUSG00000027637|Vega:OTTMUSG00000016066 +67389 C1qtnf12 MGI:MGI:1914639|Ensembl:ENSMUSG00000023571|Vega:OTTMUSG00000010985 +67390 Mrm3 MGI:MGI:1914640|Ensembl:ENSMUSG00000038046|Vega:OTTMUSG00000006229 +67391 Fundc2 MGI:MGI:1914641|Ensembl:ENSMUSG00000031198|Vega:OTTMUSG00000020855 +67392 4833420G17Rik MGI:MGI:1914642|Ensembl:ENSMUSG00000062822 +67393 Cxxc5 MGI:MGI:1914643|Ensembl:ENSMUSG00000046668 +67394 4930404I05Rik MGI:MGI:1914644|Ensembl:ENSMUSG00000087354 +67395 Ppp1r2-ps9 MGI:MGI:1914645|Ensembl:ENSMUSG00000045217 +67397 Erp29 MGI:MGI:1914647|Ensembl:ENSMUSG00000029616|Vega:OTTMUSG00000023477 +67398 Srpr MGI:MGI:1914648|Ensembl:ENSMUSG00000032042|Vega:OTTMUSG00000031587 +67399 Pdlim7 MGI:MGI:1914649|Ensembl:ENSMUSG00000021493|Vega:OTTMUSG00000032913 +67402 Txndc8 MGI:MGI:1914652|Ensembl:ENSMUSG00000038709|Vega:OTTMUSG00000007385 +67405 Nts MGI:MGI:1328351|Ensembl:ENSMUSG00000019890 +67407 Cylc1 MGI:MGI:1914657|Ensembl:ENSMUSG00000073001|Vega:OTTMUSG00000060503 +67410 4930449I24Rik MGI:MGI:1914660|Ensembl:ENSMUSG00000079093|Vega:OTTMUSG00000055155 +67412 Soga3 MGI:MGI:1914662|Ensembl:ENSMUSG00000038916|Vega:OTTMUSG00000063659 +67414 Mfn1 MGI:MGI:1914664|Ensembl:ENSMUSG00000027668|Vega:OTTMUSG00000027816 +67416 Armcx2 MGI:MGI:1914666|Ensembl:ENSMUSG00000033436|Vega:OTTMUSG00000019456 +67417 Ears2 MGI:MGI:1914667|Ensembl:ENSMUSG00000030871|Vega:OTTMUSG00000025467 +67418 Ppil4 MGI:MGI:1914668|Ensembl:ENSMUSG00000015757|Vega:OTTMUSG00000023636 +67419 3632451O06Rik MGI:MGI:1914669|Ensembl:ENSMUSG00000036242|Vega:OTTMUSG00000029972 +67420 Far1 MGI:MGI:1914670|Ensembl:ENSMUSG00000030759|Vega:OTTMUSG00000031364 +67422 Dhdds MGI:MGI:1914672|Ensembl:ENSMUSG00000012117|Vega:OTTMUSG00000009801 +67425 Eps8l1 MGI:MGI:1914675|Ensembl:ENSMUSG00000006154|Vega:OTTMUSG00000035448 +67426 Coq8a MGI:MGI:1914676|Ensembl:ENSMUSG00000026489|Vega:OTTMUSG00000034709 +67427 Rps20 MGI:MGI:1914677|Ensembl:ENSMUSG00000028234|Vega:OTTMUSG00000004410 +67429 Nudcd1 MGI:MGI:1914679|Ensembl:ENSMUSG00000038736 +67430 4921536K21Rik MGI:MGI:1914680|Ensembl:ENSMUSG00000020434|Vega:OTTMUSG00000005036 +67432 Hoga1 MGI:MGI:1914682|Ensembl:ENSMUSG00000025176|Vega:OTTMUSG00000035806 +67433 Ccdc127 MGI:MGI:1914683|Ensembl:ENSMUSG00000021578|Vega:OTTMUSG00000030725 +67434 Ankrd33b MGI:MGI:1917904|Ensembl:ENSMUSG00000022237|Vega:OTTMUSG00000032733 +67437 Ssr3 MGI:MGI:1914687|Ensembl:ENSMUSG00000027828|Vega:OTTMUSG00000028773 +67439 Xab2 MGI:MGI:1914689|Ensembl:ENSMUSG00000019470|Vega:OTTMUSG00000034606 +67440 Mtpap MGI:MGI:1914690|Ensembl:ENSMUSG00000024234 +67441 Isoc2b MGI:MGI:1914691|Ensembl:ENSMUSG00000052605|Vega:OTTMUSG00000023222 +67442 Retsat MGI:MGI:1914692|Ensembl:ENSMUSG00000056666|Vega:OTTMUSG00000026938 +67443 Map1lc3b MGI:MGI:1914693|Ensembl:ENSMUSG00000031812|Vega:OTTMUSG00000043032 +67444 Ilkap MGI:MGI:1914694|Ensembl:ENSMUSG00000026309|Vega:OTTMUSG00000048492 +67445 C1qtnf4 MGI:MGI:1914695|Ensembl:ENSMUSG00000040794|Vega:OTTMUSG00000014316 +67446 Dusp28 MGI:MGI:1914696|Ensembl:ENSMUSG00000047067|Vega:OTTMUSG00000048631 +67448 Plxdc2 MGI:MGI:1914698|Ensembl:ENSMUSG00000026748|Vega:OTTMUSG00000011395 +67451 Pkp2 MGI:MGI:1914701|Ensembl:ENSMUSG00000041957|Vega:OTTMUSG00000021016 +67452 Pnpla8 MGI:MGI:1914702|Ensembl:ENSMUSG00000036257|Vega:OTTMUSG00000033478 +67453 Slc25a46 MGI:MGI:1914703|Ensembl:ENSMUSG00000024259 +67454 Ikbip MGI:MGI:1914704|Ensembl:ENSMUSG00000019975|Vega:OTTMUSG00000027821 +67455 Klhl13 MGI:MGI:1914705|Ensembl:ENSMUSG00000036782|Vega:OTTMUSG00000017245 +67456 Ergic2 MGI:MGI:1914706|Ensembl:ENSMUSG00000030304|Vega:OTTMUSG00000023518 +67457 Frmd8 MGI:MGI:1914707|Ensembl:ENSMUSG00000024816|Vega:OTTMUSG00000033946 +67458 Ergic1 MGI:MGI:1914708|Ensembl:ENSMUSG00000001576|Vega:OTTMUSG00000035774 +67459 Nvl MGI:MGI:1914709|Ensembl:ENSMUSG00000026516|Vega:OTTMUSG00000050467 +67460 Decr1 MGI:MGI:1914710|Ensembl:ENSMUSG00000028223|Vega:OTTMUSG00000004641 +67463 Poc5 MGI:MGI:1914713|Ensembl:ENSMUSG00000021671 +67464 Entpd4 MGI:MGI:1914714|Ensembl:ENSMUSG00000095463|Vega:OTTMUSG00000044497 +67465 Sf3a1 MGI:MGI:1914715|Ensembl:ENSMUSG00000002129|Vega:OTTMUSG00000005059 +67466 Pdcl MGI:MGI:1914716|Ensembl:ENSMUSG00000009030|Vega:OTTMUSG00000012647 +67467 Gpalpp1 MGI:MGI:1914717|Ensembl:ENSMUSG00000022008 +67468 Mmd MGI:MGI:1914718|Ensembl:ENSMUSG00000003948|Vega:OTTMUSG00000060262 +67469 Abhd5 MGI:MGI:1914719|Ensembl:ENSMUSG00000032540|Vega:OTTMUSG00000022749 +67470 Abcg8 MGI:MGI:1914720|Ensembl:ENSMUSG00000024254|Vega:OTTMUSG00000036685 +67471 Gpatch1 MGI:MGI:1914721|Ensembl:ENSMUSG00000063808|Vega:OTTMUSG00000030960 +67472 Mtfr1 MGI:MGI:1914722|Ensembl:ENSMUSG00000027601|Vega:OTTMUSG00000027795 +67473 Slc47a1 MGI:MGI:1914723|Ensembl:ENSMUSG00000010122|Vega:OTTMUSG00000005831 +67474 Snap29 MGI:MGI:1914724|Ensembl:ENSMUSG00000022765|Vega:OTTMUSG00000023704 +67475 Ero1lb MGI:MGI:1914725|Ensembl:ENSMUSG00000057069 +67477 Abhd15 MGI:MGI:1914727|Ensembl:ENSMUSG00000000686|Vega:OTTMUSG00000008183 +67480 Cwc25 MGI:MGI:1914730|Ensembl:ENSMUSG00000018541|Vega:OTTMUSG00000002750 +67483 1700028P14Rik MGI:MGI:1914733|Ensembl:ENSMUSG00000033053 +67484 Eepd1 MGI:MGI:1914734|Ensembl:ENSMUSG00000036611|Vega:OTTMUSG00000027404 +67486 Polr3g MGI:MGI:1914736|Ensembl:ENSMUSG00000035834|Vega:OTTMUSG00000035047 +67487 Dhx40 MGI:MGI:1914737|Ensembl:ENSMUSG00000018425|Vega:OTTMUSG00000001202 +67488 Calcoco1 MGI:MGI:1914738|Ensembl:ENSMUSG00000023055|Vega:OTTMUSG00000035802 +67489 Ap4b1 MGI:MGI:1337130|Ensembl:ENSMUSG00000032952|Ensembl:ENSMUSG00000105053|Vega:OTTMUSG00000022451|Vega:OTTMUSG00000054936 +67490 Ufl1 MGI:MGI:1914740|Ensembl:ENSMUSG00000040359|Vega:OTTMUSG00000004799 +67492 Zfand4 MGI:MGI:1914742|Ensembl:ENSMUSG00000042213 +67493 Mettl16 MGI:MGI:1914743|Ensembl:ENSMUSG00000010554|Vega:OTTMUSG00000006186 +67495 Tmem167b MGI:MGI:1914745|Ensembl:ENSMUSG00000068732|Vega:OTTMUSG00000007256 +67498 Kcnv1 MGI:MGI:1914748|Ensembl:ENSMUSG00000022342 +67500 Ccar1 MGI:MGI:1914750|Ensembl:ENSMUSG00000020074 +67501 Ccdc50 MGI:MGI:1914751|Ensembl:ENSMUSG00000038127|Vega:OTTMUSG00000023490 +67503 1700001G17Rik MGI:MGI:1914753|Ensembl:ENSMUSG00000103746 +67504 Rnf151 MGI:MGI:1914754|Ensembl:ENSMUSG00000008482 +67505 Prl7c1 MGI:MGI:1914755|Ensembl:ENSMUSG00000060738|Vega:OTTMUSG00000000650 +67507 1700019N19Rik MGI:MGI:1914757|Ensembl:ENSMUSG00000026931|Vega:OTTMUSG00000036451 +67509 Saysd1 MGI:MGI:1914759|Ensembl:ENSMUSG00000045107 +67510 Tvp23b MGI:MGI:1914760|Ensembl:ENSMUSG00000014177|Vega:OTTMUSG00000005878 +67511 Tmed9 MGI:MGI:1914761|Ensembl:ENSMUSG00000058569 +67512 Agpat2 MGI:MGI:1914762|Ensembl:ENSMUSG00000026922|Vega:OTTMUSG00000011578 +67513 Faap20 MGI:MGI:1914763|Ensembl:ENSMUSG00000073684|Vega:OTTMUSG00000010597 +67515 Ttc33 MGI:MGI:1914765|Ensembl:ENSMUSG00000022151|Vega:OTTMUSG00000027986 +67516 Kctd4 MGI:MGI:1914766|Ensembl:ENSMUSG00000046523 +67518 1700039M10Rik MGI:MGI:1914768|Ensembl:ENSMUSG00000097933 +67522 1700097N02Rik MGI:MGI:1914772|Ensembl:ENSMUSG00000099474 +67523 1700094J05Rik MGI:MGI:1914773|Ensembl:ENSMUSG00000101695 +67524 1700095A21Rik MGI:MGI:1914774|Ensembl:ENSMUSG00000086046 +67525 Trim62 MGI:MGI:1914775|Ensembl:ENSMUSG00000041000|Vega:OTTMUSG00000009543 +67526 Atg12 MGI:MGI:1914776|Ensembl:ENSMUSG00000032905 +67527 LOC67527 - +67528 Nudt7 MGI:MGI:1914778|Ensembl:ENSMUSG00000031767|Vega:OTTMUSG00000027518 +67529 Fgfr1op2 MGI:MGI:1914779|Ensembl:ENSMUSG00000040242|Vega:OTTMUSG00000025705 +67530 Uqcrb MGI:MGI:1914780|Ensembl:ENSMUSG00000021520|Vega:OTTMUSG00000037036 +67531 5730408K05Rik MGI:MGI:1914781 +67532 Mfap1a MGI:MGI:1914782|Ensembl:ENSMUSG00000068479|Vega:OTTMUSG00000015375 +67533 Ppfibp1 MGI:MGI:1914783|Ensembl:ENSMUSG00000016487|Vega:OTTMUSG00000022991 +67534 Ttll4 MGI:MGI:1914784|Ensembl:ENSMUSG00000033257|Vega:OTTMUSG00000021753 +67537 Glipr1l2 MGI:MGI:1914787|Ensembl:ENSMUSG00000020214|Vega:OTTMUSG00000027783 +67538 Zswim3 MGI:MGI:1914788|Ensembl:ENSMUSG00000045822|Vega:OTTMUSG00000001106 +67540 4931428A05Rik MGI:MGI:1914790 +67541 4932416J16Rik MGI:MGI:1914791 +67542 Cog6 MGI:MGI:1914792|Ensembl:ENSMUSG00000027742|Vega:OTTMUSG00000051735 +67543 Pabpc6 MGI:MGI:1914793|Ensembl:ENSMUSG00000046173 +67544 Fam120b MGI:MGI:1914794|Ensembl:ENSMUSG00000014763 +67547 Slc39a8 MGI:MGI:1914797|Ensembl:ENSMUSG00000053897|Vega:OTTMUSG00000024378 +67548 4933424M12Rik MGI:MGI:1914798|Ensembl:ENSMUSG00000087289 +67549 Gpr89 MGI:MGI:1914799|Ensembl:ENSMUSG00000028096|Vega:OTTMUSG00000024701 +67550 4933416O17Rik MGI:MGI:1914800 +67551 4933409L14Rik MGI:MGI:1914801 +67552 H2afy3 MGI:MGI:1914802 +67553 Gstcd MGI:MGI:1914803|Ensembl:ENSMUSG00000028018|Vega:OTTMUSG00000023354 +67554 Slc25a30 MGI:MGI:1914804|Ensembl:ENSMUSG00000022003 +67555 Mgat4d MGI:MGI:1914805|Ensembl:ENSMUSG00000035057|Vega:OTTMUSG00000024986 +67556 Pigm MGI:MGI:1914806|Ensembl:ENSMUSG00000050229|Vega:OTTMUSG00000050149 +67557 Larp6 MGI:MGI:1914807|Ensembl:ENSMUSG00000034839|Vega:OTTMUSG00000027546 +67561 Wdr48 MGI:MGI:1914811|Ensembl:ENSMUSG00000032512|Vega:OTTMUSG00000062301 +67563 Narfl MGI:MGI:1914813|Ensembl:ENSMUSG00000002280|Vega:OTTMUSG00000033885 +67564 Tmem35a MGI:MGI:1914814|Ensembl:ENSMUSG00000033578|Vega:OTTMUSG00000019227 +67568 Mrfap1 MGI:MGI:1914818|Ensembl:ENSMUSG00000055302|Vega:OTTMUSG00000024873 +67569 Mgat4c MGI:MGI:1914819|Ensembl:ENSMUSG00000019888|Vega:OTTMUSG00000031902 +67573 Loxl4 MGI:MGI:1914823|Ensembl:ENSMUSG00000025185|Vega:OTTMUSG00000035803 +67574 Alg13 MGI:MGI:1914824|Ensembl:ENSMUSG00000041718|Vega:OTTMUSG00000018919 +67575 4930430A15Rik MGI:MGI:1914825|Ensembl:ENSMUSG00000027157|Vega:OTTMUSG00000015188 +67576 4930429B21Rik MGI:MGI:1914826 +67578 Patl2 MGI:MGI:1914828|Ensembl:ENSMUSG00000027233|Vega:OTTMUSG00000015532 +67579 Cpeb4 MGI:MGI:1914829|Ensembl:ENSMUSG00000020300|Vega:OTTMUSG00000005363 +67580 Lrrc18 MGI:MGI:1914830|Ensembl:ENSMUSG00000041673|Vega:OTTMUSG00000027915 +67581 Tbc1d23 MGI:MGI:1914831|Ensembl:ENSMUSG00000022749 +67582 Slc25a26 MGI:MGI:1914832|Ensembl:ENSMUSG00000045100|Vega:OTTMUSG00000057781 +67583 4930442L01Rik MGI:MGI:1914833|Ensembl:ENSMUSG00000087223 +67585 4930455J16Rik MGI:MGI:1914835 +67586 Ubxn11 MGI:MGI:1914836|Ensembl:ENSMUSG00000012126|Vega:OTTMUSG00000010232 +67587 Cdk19os MGI:MGI:1914837 +67588 Rnf41 MGI:MGI:1914838|Ensembl:ENSMUSG00000025373 +67589 4930518J20Rik MGI:MGI:1914839 +67590 Tctn3 MGI:MGI:1914840|Ensembl:ENSMUSG00000025008|Vega:OTTMUSG00000029015 +67591 Ubl4b MGI:MGI:1914841|Ensembl:ENSMUSG00000055891|Vega:OTTMUSG00000052962 +67592 4930524B15Rik MGI:MGI:1914842|Ensembl:ENSMUSG00000020299|Vega:OTTMUSG00000005367 +67593 4930519G04Rik MGI:MGI:1914843|Ensembl:ENSMUSG00000029564|Vega:OTTMUSG00000029077 +67596 Tespa1 MGI:MGI:1914846|Ensembl:ENSMUSG00000034833 +67602 Necap1 MGI:MGI:1914852|Ensembl:ENSMUSG00000030327|Vega:OTTMUSG00000056523 +67603 Dusp6 MGI:MGI:1914853|Ensembl:ENSMUSG00000019960 +67604 Get4 MGI:MGI:1914854|Ensembl:ENSMUSG00000025858|Vega:OTTMUSG00000025183 +67605 Akt1s1 MGI:MGI:1914855|Ensembl:ENSMUSG00000011096|Vega:OTTMUSG00000023108 +67606 Fibin MGI:MGI:1914856|Ensembl:ENSMUSG00000074971|Vega:OTTMUSG00000015130 +67607 Zfp788 MGI:MGI:1914857|Ensembl:ENSMUSG00000074165|Vega:OTTMUSG00000022450 +67608 Narf MGI:MGI:1914858|Ensembl:ENSMUSG00000000056|Vega:OTTMUSG00000004296 +67609 4930453N24Rik MGI:MGI:1914859|Ensembl:ENSMUSG00000059920|Vega:OTTMUSG00000028521 +67610 Rspry1 MGI:MGI:1914860|Ensembl:ENSMUSG00000050079|Vega:OTTMUSG00000031333 +67615 Ube2r2 MGI:MGI:1914865|Ensembl:ENSMUSG00000036241|Vega:OTTMUSG00000006640 +67618 Aasdhppt MGI:MGI:1914868|Ensembl:ENSMUSG00000025894|Vega:OTTMUSG00000061683 +67619 Nob1 MGI:MGI:1914869|Ensembl:ENSMUSG00000003848|Vega:OTTMUSG00000035977 +67620 Lrp2bp MGI:MGI:1914870|Ensembl:ENSMUSG00000031637|Vega:OTTMUSG00000022859 +67621 Bend5 MGI:MGI:1914871|Ensembl:ENSMUSG00000028545|Vega:OTTMUSG00000008488 +67622 Mxra7 MGI:MGI:1914872|Ensembl:ENSMUSG00000020814|Vega:OTTMUSG00000003781 +67623 Tm7sf3 MGI:MGI:1914873|Ensembl:ENSMUSG00000040234|Vega:OTTMUSG00000025703 +67628 Anp32b MGI:MGI:1914878|Ensembl:ENSMUSG00000028333|Vega:OTTMUSG00000006891 +67629 Spc24 MGI:MGI:1914879|Ensembl:ENSMUSG00000074476|Vega:OTTMUSG00000063570 +67630 Samd8 MGI:MGI:1914880|Ensembl:ENSMUSG00000021770|Vega:OTTMUSG00000027978 +67634 Ftmt MGI:MGI:1914884|Ensembl:ENSMUSG00000024510 +67635 4930458B22Rik MGI:MGI:1914885 +67636 Etfrf1 MGI:MGI:1914886|Ensembl:ENSMUSG00000040370|Vega:OTTMUSG00000023464 +67637 4930470P17Rik MGI:MGI:1914887|Ensembl:ENSMUSG00000043583|Vega:OTTMUSG00000016129 +67638 4930483J18Rik MGI:MGI:1914888|Ensembl:ENSMUSG00000047938 +67639 4930474N09Rik MGI:MGI:1914889|Ensembl:ENSMUSG00000113210 +67640 4930465K10Rik MGI:MGI:1914890 +67641 4930505M18Rik MGI:MGI:1914891 +67642 4930515G01Rik MGI:MGI:1914892|Ensembl:ENSMUSG00000092183 +67643 4930520E11Rik MGI:MGI:1914893 +67644 4930517G24Rik MGI:MGI:1914894 +67645 Armc12 MGI:MGI:1914895|Ensembl:ENSMUSG00000024223|Vega:OTTMUSG00000024250 +67646 4930522H14Rik MGI:MGI:1914896|Ensembl:ENSMUSG00000060491|Vega:OTTMUSG00000008513 +67647 4930523C07Rik MGI:MGI:1914897|Ensembl:ENSMUSG00000090394 +67648 4930542C12Rik MGI:MGI:1914898 +67651 4930527F14Rik MGI:MGI:1914901 +67652 Spaca1 MGI:MGI:1914902|Ensembl:ENSMUSG00000028264|Vega:OTTMUSG00000008303 +67653 4930544G11Rik MGI:MGI:1914903|Ensembl:ENSMUSG00000036463|Vega:OTTMUSG00000057253 +67654 4930558C23Rik MGI:MGI:1914904|Ensembl:ENSMUSG00000105734|Vega:OTTMUSG00000052974 +67655 Ctdp1 MGI:MGI:1926953|Ensembl:ENSMUSG00000033323|Vega:OTTMUSG00000031152 +67656 4930548H24Rik MGI:MGI:1914906|Ensembl:ENSMUSG00000029138|Vega:OTTMUSG00000028277 +67657 Rabl3 MGI:MGI:1914907|Ensembl:ENSMUSG00000022827|Vega:OTTMUSG00000025473 +67658 4930563F15Rik MGI:MGI:1914908 +67659 4930563I02Rik MGI:MGI:1914909 +67661 Ift172 MGI:MGI:2682064|Ensembl:ENSMUSG00000038564|Vega:OTTMUSG00000055210 +67663 Tex46 MGI:MGI:1914913|Ensembl:ENSMUSG00000036921|Vega:OTTMUSG00000009705 +67664 Rnf125 MGI:MGI:1914914|Ensembl:ENSMUSG00000033107 +67665 Dctn4 MGI:MGI:1914915|Ensembl:ENSMUSG00000024603 +67666 Hapln3 MGI:MGI:1914916|Ensembl:ENSMUSG00000030606|Vega:OTTMUSG00000058543 +67667 Alkbh8 MGI:MGI:1914917|Ensembl:ENSMUSG00000025899|Vega:OTTMUSG00000061662 +67668 4930563N14Rik MGI:MGI:1914918 +67669 Hikeshi MGI:MGI:96738|Ensembl:ENSMUSG00000062797|Vega:OTTMUSG00000023022 +67671 Rpl38 MGI:MGI:1914921|Ensembl:ENSMUSG00000057322|Vega:OTTMUSG00000003385 +67672 0610040B10Rik MGI:MGI:1914922|Ensembl:ENSMUSG00000089889 +67673 Elob MGI:MGI:1914923|Ensembl:ENSMUSG00000055839 +67674 Trmt112 MGI:MGI:1914924|Ensembl:ENSMUSG00000038812|Vega:OTTMUSG00000038206 +67675 Cuta MGI:MGI:1914925|Ensembl:ENSMUSG00000024194 +67676 Rpp21 MGI:MGI:1914926|Ensembl:ENSMUSG00000024446|Vega:OTTMUSG00000037272 +67678 Lsm3 MGI:MGI:1914928|Ensembl:ENSMUSG00000034192|Vega:OTTMUSG00000024129 +67679 0710001D07Rik MGI:MGI:1914929 +67680 Sdhb MGI:MGI:1914930|Ensembl:ENSMUSG00000009863|Vega:OTTMUSG00000010087 +67681 Mrpl18 MGI:MGI:1914931|Ensembl:ENSMUSG00000057388|Vega:OTTMUSG00000028084 +67683 Pbdc1 MGI:MGI:1914933|Ensembl:ENSMUSG00000031226|Vega:OTTMUSG00000018113 +67684 Luc7l3 MGI:MGI:1914934|Ensembl:ENSMUSG00000020863|Vega:OTTMUSG00000001710 +67685 Dyx1c1 MGI:MGI:1914935|Ensembl:ENSMUSG00000089865|Ensembl:ENSMUSG00000092192|Vega:OTTMUSG00000033537|Vega:OTTMUSG00000037514 +67687 1700011L22Rik MGI:MGI:1914937|Ensembl:ENSMUSG00000031682|Vega:OTTMUSG00000061303 +67689 Aldh3b1 MGI:MGI:1914939|Ensembl:ENSMUSG00000024885 +67690 Prss37 MGI:MGI:1914940|Ensembl:ENSMUSG00000029909|Vega:OTTMUSG00000026894 +67692 1700020N01Rik MGI:MGI:1914942|Ensembl:ENSMUSG00000050844|Vega:OTTMUSG00000045130 +67693 Hypk MGI:MGI:1914943|Ensembl:ENSMUSG00000027245|Vega:OTTMUSG00000015324 +67694 Ift74 MGI:MGI:1914944|Ensembl:ENSMUSG00000028576|Vega:OTTMUSG00000007856 +67695 Ost4 MGI:MGI:1914945|Ensembl:ENSMUSG00000038803|Vega:OTTMUSG00000022351 +67698 Fam174a MGI:MGI:1914948|Ensembl:ENSMUSG00000051185|Vega:OTTMUSG00000048750 +67701 Wfdc2 MGI:MGI:1914951|Ensembl:ENSMUSG00000017723|Vega:OTTMUSG00000001093 +67702 Rnf149 MGI:MGI:2677438|Ensembl:ENSMUSG00000048234|Vega:OTTMUSG00000021879 +67703 Kirrel3 MGI:MGI:1914953|Ensembl:ENSMUSG00000032036|Vega:OTTMUSG00000016800 +67704 1810037I17Rik MGI:MGI:1914954|Ensembl:ENSMUSG00000054091|Vega:OTTMUSG00000022007 +67705 1810058I24Rik MGI:MGI:1914955|Ensembl:ENSMUSG00000073155 +67706 Tmem179b MGI:MGI:1914956|Ensembl:ENSMUSG00000003680 +67707 Mrpl24 MGI:MGI:1914957|Ensembl:ENSMUSG00000019710|Vega:OTTMUSG00000027504 +67708 Pcnx4 MGI:MGI:1914958|Ensembl:ENSMUSG00000034501 +67709 Reg4 MGI:MGI:1914959|Ensembl:ENSMUSG00000027876|Vega:OTTMUSG00000028758 +67710 Polr2g MGI:MGI:1914960|Ensembl:ENSMUSG00000071662 +67711 Nsmce1 MGI:MGI:1914961|Ensembl:ENSMUSG00000030750|Vega:OTTMUSG00000029028 +67712 Slc25a37 MGI:MGI:1914962|Ensembl:ENSMUSG00000034248|Vega:OTTMUSG00000044494 +67713 Dnajc19 MGI:MGI:1914963|Ensembl:ENSMUSG00000027679|Vega:OTTMUSG00000028129 +67715 2010106E10Rik MGI:MGI:1914965|Ensembl:ENSMUSG00000025528|Vega:OTTMUSG00000018515 +67717 Lipf MGI:MGI:1914967|Ensembl:ENSMUSG00000024768|Vega:OTTMUSG00000028348 +67718 Lce1h MGI:MGI:1914968|Ensembl:ENSMUSG00000049593|Vega:OTTMUSG00000051856 +67719 2310057J18Rik MGI:MGI:1914969|Ensembl:ENSMUSG00000015519|Vega:OTTMUSG00000028053 +67722 Actl11 MGI:MGI:1914972|Ensembl:ENSMUSG00000066368|Vega:OTTMUSG00000033592 +67723 Cep83os MGI:MGI:1914973 +67724 Pop1 MGI:MGI:1914974|Ensembl:ENSMUSG00000022325|Vega:OTTMUSG00000028007 +67725 Nudt13 MGI:MGI:1914975|Ensembl:ENSMUSG00000021809 +67726 Fam114a2 MGI:MGI:1917629|Ensembl:ENSMUSG00000020523|Vega:OTTMUSG00000006324 +67727 Stx17 MGI:MGI:1914977|Ensembl:ENSMUSG00000061455|Vega:OTTMUSG00000006814 +67728 Dph2 MGI:MGI:1914978|Ensembl:ENSMUSG00000028540|Vega:OTTMUSG00000008652 +67729 Mansc1 MGI:MGI:1914979|Ensembl:ENSMUSG00000032718|Vega:OTTMUSG00000024333 +67731 Fbxo32 MGI:MGI:1914981|Ensembl:ENSMUSG00000022358 +67732 Iah1 MGI:MGI:1914982|Ensembl:ENSMUSG00000062054 +67733 Itgb3bp MGI:MGI:1914983|Ensembl:ENSMUSG00000028549|Vega:OTTMUSG00000007988 +67734 4930509G22Rik MGI:MGI:1914984 +67735 4930528A17Rik MGI:MGI:1914985 +67736 Ccdc130 MGI:MGI:1914986|Ensembl:ENSMUSG00000004994|Vega:OTTMUSG00000036549 +67737 Ttc39d MGI:MGI:1914987|Ensembl:ENSMUSG00000046196|Vega:OTTMUSG00000033673 +67738 Ppid MGI:MGI:1914988|Ensembl:ENSMUSG00000027804|Vega:OTTMUSG00000029417 +67739 Slc48a1 MGI:MGI:1914989|Ensembl:ENSMUSG00000081534|Vega:OTTMUSG00000029612 +67740 4930588J15Rik MGI:MGI:1914990 +67741 4930579F01Rik MGI:MGI:1914991|Ensembl:ENSMUSG00000012042|Vega:OTTMUSG00000052806 +67742 Samsn1 MGI:MGI:1914992|Ensembl:ENSMUSG00000022876|Vega:OTTMUSG00000023564 +67745 4930583K01Rik MGI:MGI:1914995|Ensembl:ENSMUSG00000055159 +67746 4930577N17Rik MGI:MGI:1914996|Ensembl:ENSMUSG00000087440 +67747 Ribc2 MGI:MGI:1914997|Ensembl:ENSMUSG00000022431 +67748 4930589P08Rik MGI:MGI:1914998 +67749 Mgarp MGI:MGI:1914999|Ensembl:ENSMUSG00000037161|Vega:OTTMUSG00000022051 +67750 4930578I06Rik MGI:MGI:1915000|Ensembl:ENSMUSG00000021961 +67752 Ppp1r32 MGI:MGI:1915002|Ensembl:ENSMUSG00000035179 +67753 Eqtn MGI:MGI:1915003|Ensembl:ENSMUSG00000028575|Vega:OTTMUSG00000007995 +67755 Ddx47 MGI:MGI:1915005|Ensembl:ENSMUSG00000030204|Vega:OTTMUSG00000022257 +67758 Aadac MGI:MGI:1915008|Ensembl:ENSMUSG00000027761|Vega:OTTMUSG00000022631 +67759 Plgrkt MGI:MGI:1915009|Ensembl:ENSMUSG00000016495|Vega:OTTMUSG00000033020 +67760 Slc38a2 MGI:MGI:1915010|Ensembl:ENSMUSG00000022462 +67763 Prpsap1 MGI:MGI:1915013|Ensembl:ENSMUSG00000015869|Vega:OTTMUSG00000003898 +67765 5830432E09Rik MGI:MGI:1915015|Ensembl:ENSMUSG00000097471 +67767 Jagn1 MGI:MGI:1915017|Ensembl:ENSMUSG00000051256|Vega:OTTMUSG00000023562 +67768 N6amt1 MGI:MGI:1915018|Ensembl:ENSMUSG00000044442|Vega:OTTMUSG00000026535 +67769 Gpatch2 MGI:MGI:1915019|Ensembl:ENSMUSG00000039210|Vega:OTTMUSG00000023031 +67770 Caap1 MGI:MGI:1915020|Ensembl:ENSMUSG00000028578|Vega:OTTMUSG00000007853 +67771 Arpc5 MGI:MGI:1915021|Ensembl:ENSMUSG00000008475|Vega:OTTMUSG00000022155 +67772 Chd8 MGI:MGI:1915022|Ensembl:ENSMUSG00000053754|Vega:OTTMUSG00000023392 +67773 Kat8 MGI:MGI:1915023|Ensembl:ENSMUSG00000030801|Vega:OTTMUSG00000058634 +67774 Borcs5 MGI:MGI:1915024|Ensembl:ENSMUSG00000042992|Vega:OTTMUSG00000023754 +67775 Rtp4 MGI:MGI:1915025|Ensembl:ENSMUSG00000033355|Vega:OTTMUSG00000060333 +67776 Vwa5a MGI:MGI:1915026|Ensembl:ENSMUSG00000023186|Vega:OTTMUSG00000027411 +67778 Zfp639 MGI:MGI:1915028|Ensembl:ENSMUSG00000027667|Vega:OTTMUSG00000052093 +67781 Ilf2 MGI:MGI:1915031|Ensembl:ENSMUSG00000001016|Vega:OTTMUSG00000052750 +67784 Plxnd1 MGI:MGI:2154244|Ensembl:ENSMUSG00000030123|Vega:OTTMUSG00000021239 +67785 Zmym4 MGI:MGI:1915035|Ensembl:ENSMUSG00000042446|Vega:OTTMUSG00000009279 +67786 6230424C14Rik MGI:MGI:1915036 +67788 Sfr1 MGI:MGI:1915038|Ensembl:ENSMUSG00000025066 +67789 Dalrd3 MGI:MGI:1915039|Ensembl:ENSMUSG00000019039|Vega:OTTMUSG00000050765 +67790 Rab39b MGI:MGI:1915040|Ensembl:ENSMUSG00000031202|Vega:OTTMUSG00000018905 +67791 6530411M01Rik MGI:MGI:1915041|Ensembl:ENSMUSG00000097049 +67792 Rgs8 MGI:MGI:108408|Ensembl:ENSMUSG00000042671|Vega:OTTMUSG00000021608 +67795 Rnls MGI:MGI:1915045|Ensembl:ENSMUSG00000071573|Vega:OTTMUSG00000033116 +67797 Snrnp48 MGI:MGI:1915047|Ensembl:ENSMUSG00000021431 +67800 Dgat2 MGI:MGI:1915050|Ensembl:ENSMUSG00000030747|Vega:OTTMUSG00000058927 +67801 Pllp MGI:MGI:1915051|Ensembl:ENSMUSG00000031775|Vega:OTTMUSG00000061691 +67803 Limd2 MGI:MGI:1915053|Ensembl:ENSMUSG00000040699|Vega:OTTMUSG00000003219 +67804 Snx2 MGI:MGI:1915054|Ensembl:ENSMUSG00000034484 +67808 Tprgl MGI:MGI:1915058|Ensembl:ENSMUSG00000029030|Vega:OTTMUSG00000010503 +67809 Rmdn3 MGI:MGI:1915059|Ensembl:ENSMUSG00000070730|Vega:OTTMUSG00000015760 +67811 Poldip2 MGI:MGI:1915061|Ensembl:ENSMUSG00000001100|Vega:OTTMUSG00000000137 +67812 Ubxn4 MGI:MGI:1915062|Ensembl:ENSMUSG00000026353|Vega:OTTMUSG00000049358 +67815 Sec14l2 MGI:MGI:1915065|Ensembl:ENSMUSG00000003585|Vega:OTTMUSG00000005050 +67819 Derl1 MGI:MGI:1915069|Ensembl:ENSMUSG00000022365 +67821 Atp1b4 MGI:MGI:1915071|Ensembl:ENSMUSG00000016327|Vega:OTTMUSG00000017229 +67824 Nmral1 MGI:MGI:1915074|Ensembl:ENSMUSG00000063445|Vega:OTTMUSG00000026648 +67826 Snap47 MGI:MGI:1915076|Ensembl:ENSMUSG00000009894|Vega:OTTMUSG00000005789 +67828 Lce1f MGI:MGI:1915078|Ensembl:ENSMUSG00000042124|Vega:OTTMUSG00000051854 +67830 Rer1 MGI:MGI:1915080|Ensembl:ENSMUSG00000029048|Vega:OTTMUSG00000010595 +67832 Brix1 MGI:MGI:1915082|Ensembl:ENSMUSG00000022247|Vega:OTTMUSG00000035551 +67834 Idh3a MGI:MGI:1915084|Ensembl:ENSMUSG00000032279|Vega:OTTMUSG00000063242 +67836 Wdr83 MGI:MGI:1915086|Ensembl:ENSMUSG00000005150|Vega:OTTMUSG00000029968 +67838 Dnajb11 MGI:MGI:1915088|Ensembl:ENSMUSG00000004460|Vega:OTTMUSG00000025893 +67839 Gpsm1 MGI:MGI:1915089|Ensembl:ENSMUSG00000026930|Vega:OTTMUSG00000012734 +67840 Mrpl57 MGI:MGI:1915090|Ensembl:ENSMUSG00000021967 +67841 Atg3 MGI:MGI:1915091|Ensembl:ENSMUSG00000022663|Vega:OTTMUSG00000025355 +67842 Nop9 MGI:MGI:1915092|Ensembl:ENSMUSG00000019297|Vega:OTTMUSG00000027854 +67843 Slc35a4 MGI:MGI:1915093|Ensembl:ENSMUSG00000033272|Vega:OTTMUSG00000035811 +67844 Rab32 MGI:MGI:1915094|Ensembl:ENSMUSG00000019832|Vega:OTTMUSG00000027515 +67845 Rnf115 MGI:MGI:1915095|Ensembl:ENSMUSG00000028098|Vega:OTTMUSG00000053171 +67846 Tmem39a MGI:MGI:1915096|Ensembl:ENSMUSG00000002845|Vega:OTTMUSG00000036539 +67847 Sncaip MGI:MGI:1915097|Ensembl:ENSMUSG00000024534|Vega:OTTMUSG00000042341 +67848 Ddx55 MGI:MGI:1915098|Ensembl:ENSMUSG00000029389|Vega:OTTMUSG00000024380 +67849 Cdca5 MGI:MGI:1915099|Ensembl:ENSMUSG00000024791|Vega:OTTMUSG00000017313 +67850 1700007F19Rik MGI:MGI:1915100|Ensembl:ENSMUSG00000100666 +67851 1700021F05Rik MGI:MGI:1915101|Ensembl:ENSMUSG00000019797|Vega:OTTMUSG00000032591 +67854 Slco6b1 MGI:MGI:1915104|Ensembl:ENSMUSG00000045463 +67855 Asprv1 MGI:MGI:1915105|Ensembl:ENSMUSG00000033508|Vega:OTTMUSG00000056543 +67856 Echdc3 MGI:MGI:1915106|Ensembl:ENSMUSG00000039063|Vega:OTTMUSG00000011754 +67857 Ppp6c MGI:MGI:1915107|Ensembl:ENSMUSG00000026753|Vega:OTTMUSG00000012451 +67859 Cysrt1 MGI:MGI:1915109|Ensembl:ENSMUSG00000036731|Vega:OTTMUSG00000011886 +67860 S100a16 MGI:MGI:1915110|Ensembl:ENSMUSG00000074457|Vega:OTTMUSG00000021998 +67861 Akr1b10 MGI:MGI:1915111|Ensembl:ENSMUSG00000061758|Vega:OTTMUSG00000014789 +67862 2310033P09Rik MGI:MGI:1915112|Ensembl:ENSMUSG00000020441|Vega:OTTMUSG00000005780 +67863 Slc25a11 MGI:MGI:1915113|Ensembl:ENSMUSG00000014606|Vega:OTTMUSG00000006069 +67864 Yipf4 MGI:MGI:1915114|Ensembl:ENSMUSG00000024072 +67865 Rgs10 MGI:MGI:1915115|Ensembl:ENSMUSG00000030844|Vega:OTTMUSG00000022902 +67866 Wfdc1 MGI:MGI:1915116|Ensembl:ENSMUSG00000023336|Vega:OTTMUSG00000061643 +67867 Lrrc28 MGI:MGI:1915689|Ensembl:ENSMUSG00000030556|Vega:OTTMUSG00000045100 +67868 Cela3b MGI:MGI:1915118|Ensembl:ENSMUSG00000023433|Vega:OTTMUSG00000009879 +67869 Paip2 MGI:MGI:1915119|Ensembl:ENSMUSG00000037058|Vega:OTTMUSG00000023945 +67870 Enoph1 MGI:MGI:1915120|Ensembl:ENSMUSG00000029326|Vega:OTTMUSG00000053572 +67871 Mrrf MGI:MGI:1915121|Ensembl:ENSMUSG00000026887|Vega:OTTMUSG00000012096 +67872 Nsmce4a MGI:MGI:1915122|Ensembl:ENSMUSG00000040331|Vega:OTTMUSG00000035026 +67873 Mri1 MGI:MGI:1915123|Ensembl:ENSMUSG00000004996|Vega:OTTMUSG00000032850 +67874 Rprm MGI:MGI:1915124|Ensembl:ENSMUSG00000075334|Vega:OTTMUSG00000012457 +67876 Coq10b MGI:MGI:1915126|Ensembl:ENSMUSG00000025981|Vega:OTTMUSG00000046967 +67877 Naa20 MGI:MGI:1915127|Ensembl:ENSMUSG00000002728|Vega:OTTMUSG00000004059 +67878 Tmem33 MGI:MGI:1915128|Ensembl:ENSMUSG00000037720|Vega:OTTMUSG00000028123 +67880 Dcxr MGI:MGI:1915130|Ensembl:ENSMUSG00000039450|Vega:OTTMUSG00000004121 +67881 Mdp1 MGI:MGI:1915131|Ensembl:ENSMUSG00000002329 +67883 Uxs1 MGI:MGI:1915133|Ensembl:ENSMUSG00000057363|Vega:OTTMUSG00000030350 +67884 1810043G02Rik MGI:MGI:1915134|Ensembl:ENSMUSG00000020284|Vega:OTTMUSG00000020324 +67885 1500011K16Rik MGI:MGI:1915135|Ensembl:ENSMUSG00000051319|Vega:OTTMUSG00000016098 +67886 Camsap2 MGI:MGI:1922434|Ensembl:ENSMUSG00000041570|Vega:OTTMUSG00000049850 +67887 Saraf MGI:MGI:1915137|Ensembl:ENSMUSG00000031532|Vega:OTTMUSG00000061000 +67888 Tmem100 MGI:MGI:1915138|Ensembl:ENSMUSG00000069763|Vega:OTTMUSG00000001282 +67889 Rbm18 MGI:MGI:1915139|Ensembl:ENSMUSG00000026889|Vega:OTTMUSG00000012099 +67890 Ufm1 MGI:MGI:1915140|Ensembl:ENSMUSG00000027746|Vega:OTTMUSG00000028195 +67891 Rpl4 MGI:MGI:1915141|Ensembl:ENSMUSG00000032399|Vega:OTTMUSG00000062590 +67892 Coa6 MGI:MGI:1915142|Ensembl:ENSMUSG00000051671|Vega:OTTMUSG00000061600 +67893 Tmem86a MGI:MGI:1915143|Ensembl:ENSMUSG00000010307|Vega:OTTMUSG00000058662 +67894 Fam45a MGI:MGI:1915144|Ensembl:ENSMUSG00000024993|Vega:OTTMUSG00000028236 +67895 Ppa1 MGI:MGI:97831|Ensembl:ENSMUSG00000020089|Vega:OTTMUSG00000035023 +67896 Ccdc80 MGI:MGI:1915146|Ensembl:ENSMUSG00000022665|Vega:OTTMUSG00000025346 +67897 Rnmt MGI:MGI:1915147|Ensembl:ENSMUSG00000009535|Vega:OTTMUSG00000023941 +67898 Pef1 MGI:MGI:1915148|Ensembl:ENSMUSG00000028779|Vega:OTTMUSG00000009515 +67899 Cmc1 MGI:MGI:1915149|Ensembl:ENSMUSG00000039163|Vega:OTTMUSG00000062899 +67900 Mtfp1 MGI:MGI:1916686|Ensembl:ENSMUSG00000004748|Vega:OTTMUSG00000005047 +67902 Sumf2 MGI:MGI:1915152|Ensembl:ENSMUSG00000025538|Vega:OTTMUSG00000023993 +67903 Gipc1 MGI:MGI:1926252|Ensembl:ENSMUSG00000019433|Vega:OTTMUSG00000061609 +67905 Ppm1m MGI:MGI:1915155|Ensembl:ENSMUSG00000020253|Vega:OTTMUSG00000033433 +67909 Galntl5 MGI:MGI:1915159|Ensembl:ENSMUSG00000028938|Vega:OTTMUSG00000024210 +67911 Zfp169 MGI:MGI:1915161|Ensembl:ENSMUSG00000050954|Vega:OTTMUSG00000038565 +67912 1600012H06Rik MGI:MGI:1915162|Ensembl:ENSMUSG00000050088|Vega:OTTMUSG00000037025 +67914 Coq9 MGI:MGI:1915164|Ensembl:ENSMUSG00000031782|Vega:OTTMUSG00000027370 +67916 Plpp3 MGI:MGI:1915166|Ensembl:ENSMUSG00000028517|Vega:OTTMUSG00000008128 +67917 Zcchc3 MGI:MGI:1915167|Ensembl:ENSMUSG00000074682|Vega:OTTMUSG00000015828 +67920 Mak16 MGI:MGI:1915170|Ensembl:ENSMUSG00000031578|Vega:OTTMUSG00000060916 +67921 Ube2f MGI:MGI:1915171|Ensembl:ENSMUSG00000034343|Vega:OTTMUSG00000048490 +67922 Fam32a MGI:MGI:1915172|Ensembl:ENSMUSG00000003039|Vega:OTTMUSG00000062097 +67923 Eloc MGI:MGI:1915173|Ensembl:ENSMUSG00000079658|Vega:OTTMUSG00000048076 +67925 1700066D14Rik MGI:MGI:1915175 +67926 Spert MGI:MGI:1915176|Ensembl:ENSMUSG00000034913 +67927 1700096J18Rik MGI:MGI:1915177|Ensembl:ENSMUSG00000099630 +67928 Abca14 MGI:MGI:2388708|Ensembl:ENSMUSG00000062017|Vega:OTTMUSG00000022558 +67929 Ccdc70 MGI:MGI:1915179|Ensembl:ENSMUSG00000017049|Vega:OTTMUSG00000020832 +67931 Serpini2 MGI:MGI:1915181|Ensembl:ENSMUSG00000034139|Vega:OTTMUSG00000026707 +67932 1700129C05Rik MGI:MGI:1915182|Ensembl:ENSMUSG00000021977|Vega:OTTMUSG00000034199 +67933 Hcfc2 MGI:MGI:1915183|Ensembl:ENSMUSG00000020246|Vega:OTTMUSG00000032504 +67934 1700124L16Rik MGI:MGI:1915184|Ensembl:ENSMUSG00000099354 +67935 Ces5a MGI:MGI:1915185|Ensembl:ENSMUSG00000058019|Vega:OTTMUSG00000061560 +67936 Wdr55 MGI:MGI:1915186|Ensembl:ENSMUSG00000042660 +67937 Tmem59l MGI:MGI:1915187|Ensembl:ENSMUSG00000035964|Vega:OTTMUSG00000061442 +67938 Myl12b MGI:MGI:107494|Ensembl:ENSMUSG00000034868|Vega:OTTMUSG00000016301 +67939 Prorsd1 MGI:MGI:1915189|Ensembl:ENSMUSG00000032673|Vega:OTTMUSG00000005328 +67941 Rps27l MGI:MGI:1915191|Ensembl:ENSMUSG00000036781|Vega:OTTMUSG00000033768 +67942 Atp5g2 MGI:MGI:1915192|Ensembl:ENSMUSG00000062683|Vega:OTTMUSG00000047926 +67943 Mesd MGI:MGI:1891421|Ensembl:ENSMUSG00000038503|Vega:OTTMUSG00000030366 +67944 Tex13a MGI:MGI:1915194|Ensembl:ENSMUSG00000071686|Vega:OTTMUSG00000018678 +67945 Rpl41 MGI:MGI:1915195|Ensembl:ENSMUSG00000093674|Vega:OTTMUSG00000042126 +67946 Spata6 MGI:MGI:1915196|Ensembl:ENSMUSG00000034401|Vega:OTTMUSG00000009477 +67948 Fbxo28 MGI:MGI:1261890|Ensembl:ENSMUSG00000047539|Vega:OTTMUSG00000050383 +67949 Nifk MGI:MGI:1915199|Ensembl:ENSMUSG00000026377|Vega:OTTMUSG00000034779 +67951 Tubb6 MGI:MGI:1915201|Ensembl:ENSMUSG00000001473 +67952 Tomm20 MGI:MGI:1915202|Ensembl:ENSMUSG00000093904|Vega:OTTMUSG00000061628 +67955 Sugt1 MGI:MGI:1915205|Ensembl:ENSMUSG00000022024 +67956 Kmt5a MGI:MGI:1915206|Ensembl:ENSMUSG00000049327|Vega:OTTMUSG00000017165 +67958 U2surp MGI:MGI:1915208|Ensembl:ENSMUSG00000032407|Vega:OTTMUSG00000047001 +67959 Puf60 MGI:MGI:1915209|Ensembl:ENSMUSG00000002524 +67963 Npc2 MGI:MGI:1915213|Ensembl:ENSMUSG00000021242 +67966 Zcchc10 MGI:MGI:1196228|Ensembl:ENSMUSG00000018239|Vega:OTTMUSG00000000050 +67967 Pold3 MGI:MGI:1915217|Ensembl:ENSMUSG00000030726|Vega:OTTMUSG00000025292 +67968 Ooep MGI:MGI:1915218|Ensembl:ENSMUSG00000032346|Vega:OTTMUSG00000019689 +67969 2700080J24Rik MGI:MGI:1915219 +67971 Tppp3 MGI:MGI:1915221|Ensembl:ENSMUSG00000014846|Vega:OTTMUSG00000042173 +67972 Atp2b1 MGI:MGI:104653|Ensembl:ENSMUSG00000019943 +67973 Mphosph10 MGI:MGI:1915223|Ensembl:ENSMUSG00000030521|Vega:OTTMUSG00000024938 +67974 Ccny MGI:MGI:1915224|Ensembl:ENSMUSG00000024286 +67976 Trabd MGI:MGI:1915226|Ensembl:ENSMUSG00000015363|Vega:OTTMUSG00000036749 +67978 Tctn2 MGI:MGI:1915228 +67979 Atad1 MGI:MGI:1915229|Ensembl:ENSMUSG00000013662 +67980 Gnpda2 MGI:MGI:1915230|Ensembl:ENSMUSG00000029209|Vega:OTTMUSG00000027748 +67981 Hormad1 MGI:MGI:1915231|Ensembl:ENSMUSG00000028109|Vega:OTTMUSG00000022048 +67983 Pdzd9 MGI:MGI:1915233|Ensembl:ENSMUSG00000030887|Vega:OTTMUSG00000025575 +67984 4930415O11Rik MGI:MGI:1915234 +67985 Ssxb1 MGI:MGI:1915235|Ensembl:ENSMUSG00000079705|Vega:OTTMUSG00000016667 +67988 Tmx3 MGI:MGI:2442418|Ensembl:ENSMUSG00000024614 +67991 Nacc2 MGI:MGI:1915241|Ensembl:ENSMUSG00000026932|Vega:OTTMUSG00000012735 +67993 Nudt12 MGI:MGI:1915243|Ensembl:ENSMUSG00000024228|Vega:OTTMUSG00000033656 +67994 Mrps11 MGI:MGI:1915244|Ensembl:ENSMUSG00000030611|Vega:OTTMUSG00000023298 +67996 Srsf6 MGI:MGI:1915246|Ensembl:ENSMUSG00000016921|Vega:OTTMUSG00000001060 +67997 Ddx59 MGI:MGI:1915247|Ensembl:ENSMUSG00000026404|Vega:OTTMUSG00000021585 +67998 Retreg3 MGI:MGI:1915248|Ensembl:ENSMUSG00000017802|Vega:OTTMUSG00000002686 +68001 1110004E09Rik MGI:MGI:1915251|Ensembl:ENSMUSG00000022972|Vega:OTTMUSG00000019913 +68002 Sdhaf4 MGI:MGI:1915252|Ensembl:ENSMUSG00000026154|Vega:OTTMUSG00000022115 +68009 Defa20 MGI:MGI:1915259|Ensembl:ENSMUSG00000095066|Vega:OTTMUSG00000019856 +68010 Bambi MGI:MGI:1915260|Ensembl:ENSMUSG00000024232 +68011 Snrpg MGI:MGI:1915261|Ensembl:ENSMUSG00000057278|Vega:OTTMUSG00000056436 +68014 Zwilch MGI:MGI:1915264|Ensembl:ENSMUSG00000032400|Vega:OTTMUSG00000028817 +68015 Trap1 MGI:MGI:1915265|Ensembl:ENSMUSG00000005981|Vega:OTTMUSG00000020070 +68016 Cavin4 MGI:MGI:1915266|Ensembl:ENSMUSG00000028348|Vega:OTTMUSG00000006855 +68017 Mrm2 MGI:MGI:1915267|Ensembl:ENSMUSG00000029557|Vega:OTTMUSG00000025889 +68018 Col4a3bp MGI:MGI:1915268|Ensembl:ENSMUSG00000021669 +68020 Apopt1 MGI:MGI:1915270|Ensembl:ENSMUSG00000037787|Vega:OTTMUSG00000028787 +68021 Bphl MGI:MGI:1915271|Ensembl:ENSMUSG00000038286 +68023 Pdf MGI:MGI:1915273|Ensembl:ENSMUSG00000078931|Vega:OTTMUSG00000031757 +68024 Hist1h2bc MGI:MGI:1915274|Ensembl:ENSMUSG00000018102|Vega:OTTMUSG00000000566 +68026 Pclaf MGI:MGI:1915276|Ensembl:ENSMUSG00000040204|Vega:OTTMUSG00000029849 +68027 Tmem178 MGI:MGI:1915277|Ensembl:ENSMUSG00000024245 +68028 Rpl22l1 MGI:MGI:1915278|Ensembl:ENSMUSG00000039221|Vega:OTTMUSG00000051223 +68031 Rnf146 MGI:MGI:1915281|Ensembl:ENSMUSG00000038876|Vega:OTTMUSG00000028056 +68032 Emc4 MGI:MGI:1915282|Ensembl:ENSMUSG00000027131|Vega:OTTMUSG00000015140 +68033 Cox19 MGI:MGI:1915283|Ensembl:ENSMUSG00000045438|Vega:OTTMUSG00000023069 +68034 Fam122a MGI:MGI:1915284|Ensembl:ENSMUSG00000074922 +68035 Rbm42 MGI:MGI:1915285|Ensembl:ENSMUSG00000036733|Vega:OTTMUSG00000026179 +68036 Zfp706 MGI:MGI:1915286|Ensembl:ENSMUSG00000062397 +68037 2900093K20Rik MGI:MGI:1915287 +68038 Chid1 MGI:MGI:1915288|Ensembl:ENSMUSG00000025512|Vega:OTTMUSG00000028950 +68039 Nmb MGI:MGI:1915289|Ensembl:ENSMUSG00000025723|Vega:OTTMUSG00000031329 +68040 Zfp593 MGI:MGI:1915290|Ensembl:ENSMUSG00000028840|Vega:OTTMUSG00000010564 +68041 Mid1ip1 MGI:MGI:1915291|Ensembl:ENSMUSG00000008035|Vega:OTTMUSG00000016740 +68043 Eef1akmt1 MGI:MGI:1915293|Ensembl:ENSMUSG00000021951 +68044 Chac2 MGI:MGI:1915294|Ensembl:ENSMUSG00000020309|Vega:OTTMUSG00000005351 +68045 2700060E02Rik MGI:MGI:1915295|Ensembl:ENSMUSG00000021807 +68046 2700062C07Rik MGI:MGI:1915296|Ensembl:ENSMUSG00000024273 +68047 Mpnd MGI:MGI:1915297|Ensembl:ENSMUSG00000003199|Vega:OTTMUSG00000033047 +68048 Aen MGI:MGI:1915298|Ensembl:ENSMUSG00000030609|Vega:OTTMUSG00000025063 +68050 Akirin1 MGI:MGI:1915300|Ensembl:ENSMUSG00000023075|Vega:OTTMUSG00000008998 +68051 Nutf2 MGI:MGI:1915301|Ensembl:ENSMUSG00000008450|Vega:OTTMUSG00000062062 +68052 Rps13 MGI:MGI:1915302|Ensembl:ENSMUSG00000090862|Vega:OTTMUSG00000058788 +68053 Ubxn2b MGI:MGI:1915303|Ensembl:ENSMUSG00000028243|Vega:OTTMUSG00000004319 +68054 Serpina12 MGI:MGI:1915304|Ensembl:ENSMUSG00000041567|Vega:OTTMUSG00000027616 +68055 Atp5s MGI:MGI:1915305|Ensembl:ENSMUSG00000054894 +68058 Chd1l MGI:MGI:1915308|Ensembl:ENSMUSG00000028089|Vega:OTTMUSG00000053233 +68059 Tm9sf2 MGI:MGI:1915309|Ensembl:ENSMUSG00000025544|Vega:OTTMUSG00000035868 +68066 Slc25a39 MGI:MGI:1196386|Ensembl:ENSMUSG00000018677|Vega:OTTMUSG00000002817 +68067 Mrnip MGI:MGI:1915317|Ensembl:ENSMUSG00000020381|Vega:OTTMUSG00000005579 +68070 Pdzd2 MGI:MGI:1922394|Ensembl:ENSMUSG00000022197|Vega:OTTMUSG00000048303 +68073 Fam173b MGI:MGI:1915323|Ensembl:ENSMUSG00000039065|Vega:OTTMUSG00000030807 +68074 A930013F10Rik MGI:MGI:1915324 +68075 Lurap1 MGI:MGI:1915325|Ensembl:ENSMUSG00000028701|Vega:OTTMUSG00000009308 +68077 Nop53 MGI:MGI:2154441|Ensembl:ENSMUSG00000041560|Vega:OTTMUSG00000054202 +68079 Pdcd2l MGI:MGI:1915329|Ensembl:ENSMUSG00000002635|Vega:OTTMUSG00000008373 +68080 Gpn3 MGI:MGI:1289326|Ensembl:ENSMUSG00000029464|Vega:OTTMUSG00000026635 +68082 Dusp19 MGI:MGI:1915332|Ensembl:ENSMUSG00000027001|Vega:OTTMUSG00000013368 +68083 Pak1ip1 MGI:MGI:1915333|Ensembl:ENSMUSG00000038683|Vega:OTTMUSG00000037930 +68087 Dcakd MGI:MGI:1915337|Ensembl:ENSMUSG00000020935|Vega:OTTMUSG00000003160 +68089 Arpc4 MGI:MGI:1915339|Ensembl:ENSMUSG00000079426|Vega:OTTMUSG00000016376 +68090 Yif1a MGI:MGI:1915340|Ensembl:ENSMUSG00000024875 +68092 Ncbp2 MGI:MGI:1915342|Ensembl:ENSMUSG00000022774|Vega:OTTMUSG00000025443 +68094 Smarcc2 MGI:MGI:1915344|Ensembl:ENSMUSG00000025369 +68095 Ociad1 MGI:MGI:1915345|Ensembl:ENSMUSG00000029152|Vega:OTTMUSG00000055923 +68097 Dynll2 MGI:MGI:1915347|Ensembl:ENSMUSG00000020483|Vega:OTTMUSG00000001475 +68098 Rchy1 MGI:MGI:1915348|Ensembl:ENSMUSG00000029397|Vega:OTTMUSG00000020371 +68099 Fam92a MGI:MGI:1915349|Ensembl:ENSMUSG00000028218|Vega:OTTMUSG00000004598 +68106 Nt5c3b MGI:MGI:1915356|Ensembl:ENSMUSG00000017176|Vega:OTTMUSG00000006268 +68107 Cntd1 MGI:MGI:1923965|Ensembl:ENSMUSG00000078653|Vega:OTTMUSG00000002763 +68108 Snhg17 MGI:MGI:1915358 +68112 Sdccag3 MGI:MGI:1915362|Ensembl:ENSMUSG00000026927|Vega:OTTMUSG00000012776 +68114 Mum1 MGI:MGI:1915364|Ensembl:ENSMUSG00000020156|Vega:OTTMUSG00000000010 +68115 Maip1 MGI:MGI:1915365|Ensembl:ENSMUSG00000025971|Vega:OTTMUSG00000029760 +68117 Apool MGI:MGI:1915367|Ensembl:ENSMUSG00000025525|Vega:OTTMUSG00000018460 +68118 Atg101 MGI:MGI:1915368|Ensembl:ENSMUSG00000037204 +68119 Cmtm3 MGI:MGI:2447162|Ensembl:ENSMUSG00000031875|Vega:OTTMUSG00000061906 +68121 Cep70 MGI:MGI:1915371|Ensembl:ENSMUSG00000056267|Vega:OTTMUSG00000048233 +68126 Fahd2a MGI:MGI:1915376|Ensembl:ENSMUSG00000027371|Vega:OTTMUSG00000016026 +68127 B230217C12Rik MGI:MGI:1915377|Ensembl:ENSMUSG00000050538 +68128 Fam120aos MGI:MGI:1915378 +68133 Gcsh MGI:MGI:1915383|Ensembl:ENSMUSG00000034424|Vega:OTTMUSG00000027530 +68134 Upf3b MGI:MGI:1915384|Ensembl:ENSMUSG00000036572|Vega:OTTMUSG00000017109 +68135 Eif3h MGI:MGI:1915385|Ensembl:ENSMUSG00000022312 +68137 Kdelr1 MGI:MGI:1915387|Ensembl:ENSMUSG00000002778|Vega:OTTMUSG00000022310 +68140 Tigd2 MGI:MGI:1915390|Ensembl:ENSMUSG00000049232|Vega:OTTMUSG00000037124 +68142 Ino80 MGI:MGI:1915392|Ensembl:ENSMUSG00000034154|Vega:OTTMUSG00000015947 +68144 5031426D15Rik MGI:MGI:1915394 +68145 Etaa1 MGI:MGI:1915395|Ensembl:ENSMUSG00000016984|Vega:OTTMUSG00000005201 +68146 Arl13b MGI:MGI:1915396|Ensembl:ENSMUSG00000022911|Vega:OTTMUSG00000024090 +68147 Gar1 MGI:MGI:1930948|Ensembl:ENSMUSG00000028010|Vega:OTTMUSG00000028857 +68149 Otub2 MGI:MGI:1915399|Ensembl:ENSMUSG00000021203|Vega:OTTMUSG00000023000 +68151 Wls MGI:MGI:1915401|Ensembl:ENSMUSG00000028173|Vega:OTTMUSG00000052834 +68152 Fam133b MGI:MGI:1915402|Ensembl:ENSMUSG00000058503|Vega:OTTMUSG00000052970 +68153 Gtf2e2 MGI:MGI:1915403|Ensembl:ENSMUSG00000031585|Vega:OTTMUSG00000049715 +68157 6720475J19Rik MGI:MGI:1915407 +68159 Stx19 MGI:MGI:1915409|Ensembl:ENSMUSG00000047854|Vega:OTTMUSG00000024089 +68161 A930005H10Rik MGI:MGI:1915411|Ensembl:ENSMUSG00000054426 +68162 A930003A15Rik MGI:MGI:1915412 +68163 A930006D01Rik MGI:MGI:1915413 +68164 A430106A12Rik MGI:MGI:1915414 +68165 Fdx1l MGI:MGI:1915415|Ensembl:ENSMUSG00000079677|Vega:OTTMUSG00000063230 +68166 Spire1 MGI:MGI:1915416|Ensembl:ENSMUSG00000024533 +68168 A930009E08Rik MGI:MGI:1915418 +68169 Ndnf MGI:MGI:1915419|Ensembl:ENSMUSG00000049001|Vega:OTTMUSG00000035342 +68170 B230118H07Rik MGI:MGI:1915420|Ensembl:ENSMUSG00000027165|Vega:OTTMUSG00000014583 +68171 D730048I06Rik MGI:MGI:1915421|Ensembl:ENSMUSG00000032108|Vega:OTTMUSG00000044685 +68172 Rpl39l MGI:MGI:1915422|Ensembl:ENSMUSG00000039209|Vega:OTTMUSG00000027599 +68173 Ppifos MGI:MGI:1915423 +68174 4930534H18Rik MGI:MGI:1915424 +68175 4930591A17Rik MGI:MGI:1915425 +68176 Fam212a MGI:MGI:1915426|Ensembl:ENSMUSG00000042106|Vega:OTTMUSG00000042013 +68177 Ebpl MGI:MGI:1915427|Ensembl:ENSMUSG00000021928 +68178 Cgnl1 MGI:MGI:1915428|Ensembl:ENSMUSG00000032232|Vega:OTTMUSG00000031674 +68180 Hyi MGI:MGI:1915430|Ensembl:ENSMUSG00000006395|Vega:OTTMUSG00000008719 +68183 Bcas2 MGI:MGI:1915433|Ensembl:ENSMUSG00000005687|Vega:OTTMUSG00000027237 +68184 Denr MGI:MGI:1915434|Ensembl:ENSMUSG00000023106|Vega:OTTMUSG00000035338 +68185 Coa4 MGI:MGI:1915435|Ensembl:ENSMUSG00000044881|Vega:OTTMUSG00000029526 +68187 Fam135a MGI:MGI:1915437|Ensembl:ENSMUSG00000026153|Vega:OTTMUSG00000046269 +68188 Sympk MGI:MGI:1915438|Ensembl:ENSMUSG00000023118|Vega:OTTMUSG00000022696 +68189 5330431K02Rik MGI:MGI:1915439 +68190 Dubr MGI:MGI:1915440 +68191 Taco1os MGI:MGI:1915441 +68192 Leprotl1 MGI:MGI:1915442|Ensembl:ENSMUSG00000031513|Vega:OTTMUSG00000031292 +68193 Rpl24 MGI:MGI:1915443|Ensembl:ENSMUSG00000098274|Vega:OTTMUSG00000025840 +68194 Ndufb4 MGI:MGI:1915444|Ensembl:ENSMUSG00000022820|Vega:OTTMUSG00000025712 +68195 Rnaset2b MGI:MGI:3702087|Ensembl:ENSMUSG00000094724 +68196 Hsbp1 MGI:MGI:1915446|Ensembl:ENSMUSG00000031839|Vega:OTTMUSG00000061637 +68197 Ndufc2 MGI:MGI:1344370|Ensembl:ENSMUSG00000030647|Vega:OTTMUSG00000029541 +68198 Ndufb2 MGI:MGI:1915448|Ensembl:ENSMUSG00000002416|Vega:OTTMUSG00000026896 +68201 Ccdc34 MGI:MGI:1915451|Ensembl:ENSMUSG00000027160|Vega:OTTMUSG00000015056 +68202 Ndufa5 MGI:MGI:1915452|Ensembl:ENSMUSG00000023089|Vega:OTTMUSG00000026861 +68203 Diras2 MGI:MGI:1915453|Ensembl:ENSMUSG00000047842 +68204 2900060B14Rik MGI:MGI:1915454|Ensembl:ENSMUSG00000107722 +68205 Urm1 MGI:MGI:1915455|Ensembl:ENSMUSG00000069020|Vega:OTTMUSG00000012687 +68206 2900060N18Rik MGI:MGI:1915456 +68207 1700040A12Rik MGI:MGI:1915457 +68208 1700039O17Rik MGI:MGI:1915458 +68209 Rnaseh2c MGI:MGI:1915459|Ensembl:ENSMUSG00000024925|Vega:OTTMUSG00000020425 +68212 Tmbim4 MGI:MGI:1915462|Ensembl:ENSMUSG00000020225|Vega:OTTMUSG00000034095 +68214 Gsto2 MGI:MGI:1915464|Ensembl:ENSMUSG00000025069|Vega:OTTMUSG00000028267 +68215 Fam98b MGI:MGI:1915465|Ensembl:ENSMUSG00000027349|Vega:OTTMUSG00000014826 +68219 Nudt21 MGI:MGI:1915469|Ensembl:ENSMUSG00000031754|Vega:OTTMUSG00000061594 +68220 1700019A23Rik MGI:MGI:1915470 +68221 Wfdc15a MGI:MGI:1915471|Ensembl:ENSMUSG00000051769|Vega:OTTMUSG00000001081 +68222 Fam166a MGI:MGI:3605773|Ensembl:ENSMUSG00000026969|Vega:OTTMUSG00000011807 +68223 Fam24a MGI:MGI:1915473|Ensembl:ENSMUSG00000030859|Vega:OTTMUSG00000059799 +68224 1700067P10Rik MGI:MGI:1915474|Ensembl:ENSMUSG00000021545 +68225 1700055K11Rik MGI:MGI:1915475 +68226 Efcab2 MGI:MGI:1915476|Ensembl:ENSMUSG00000026495|Vega:OTTMUSG00000050382 +68227 1700082C02Rik MGI:MGI:1915477 +68228 1700095K22Rik MGI:MGI:1915478 +68229 AI846148 MGI:MGI:2147611|Ensembl:ENSMUSG00000024970 +68230 1700102H20Rik MGI:MGI:1915480 +68231 H2afb1 MGI:MGI:1915481|Ensembl:ENSMUSG00000062651|Vega:OTTMUSG00000011459 +68232 1700120K04Rik MGI:MGI:1915482|Ensembl:ENSMUSG00000099579 +68233 Fam229a MGI:MGI:1915483|Ensembl:ENSMUSG00000078554|Vega:OTTMUSG00000009657 +68235 Mturn MGI:MGI:1915485|Ensembl:ENSMUSG00000038065|Vega:OTTMUSG00000047435 +68236 Gtsf1l MGI:MGI:1915486|Ensembl:ENSMUSG00000070708|Vega:OTTMUSG00000001064 +68238 1700123O21Rik MGI:MGI:1915488|Ensembl:ENSMUSG00000101481 +68239 Krt42 MGI:MGI:1915489|Ensembl:ENSMUSG00000053654|Vega:OTTMUSG00000002542 +68240 Rpa3 MGI:MGI:1915490|Ensembl:ENSMUSG00000012483|Vega:OTTMUSG00000029297 +68241 Mcrip2 MGI:MGI:1915491|Ensembl:ENSMUSG00000025732 +68243 A930018P22Rik MGI:MGI:1915493|Ensembl:ENSMUSG00000032671|Vega:OTTMUSG00000014933 +68245 1700108J01Rik MGI:MGI:1915495|Ensembl:ENSMUSG00000100585 +68246 1700112J05Rik MGI:MGI:3696786|Ensembl:ENSMUSG00000086632 +68250 Fam96a MGI:MGI:1915500|Ensembl:ENSMUSG00000032381|Vega:OTTMUSG00000021048 +68251 Babam1 MGI:MGI:1915501|Ensembl:ENSMUSG00000031820|Vega:OTTMUSG00000062154 +68255 Tmem86b MGI:MGI:1915505|Ensembl:ENSMUSG00000045282|Vega:OTTMUSG00000058446 +68259 Ift80 MGI:MGI:1915509|Ensembl:ENSMUSG00000027778|Vega:OTTMUSG00000024494 +68260 Trmt12 MGI:MGI:1915510|Ensembl:ENSMUSG00000037085 +68262 Agpat4 MGI:MGI:1915512|Ensembl:ENSMUSG00000023827|Vega:OTTMUSG00000036581 +68263 Pdhb MGI:MGI:1915513|Ensembl:ENSMUSG00000021748 +68265 Iqcf3 MGI:MGI:1915515|Ensembl:ENSMUSG00000023577|Vega:OTTMUSG00000049442 +68267 Slc25a22 MGI:MGI:1915517|Ensembl:ENSMUSG00000019082|Vega:OTTMUSG00000016510 +68268 Zdhhc21 MGI:MGI:1915518|Ensembl:ENSMUSG00000028403|Vega:OTTMUSG00000000297 +68270 Dnaaf1 MGI:MGI:1915520|Ensembl:ENSMUSG00000031831|Vega:OTTMUSG00000031110 +68271 Zfp85os MGI:MGI:1915521 +68272 Rbm28 MGI:MGI:2655711|Ensembl:ENSMUSG00000029701|Vega:OTTMUSG00000035837 +68273 Pomgnt1 MGI:MGI:1915523|Ensembl:ENSMUSG00000028700|Vega:OTTMUSG00000009309 +68274 Toporsl MGI:MGI:1915524|Ensembl:ENSMUSG00000028314|Vega:OTTMUSG00000007058 +68275 Rpa1 MGI:MGI:1915525|Ensembl:ENSMUSG00000000751|Vega:OTTMUSG00000006199 +68276 Toe1 MGI:MGI:1915526|Ensembl:ENSMUSG00000028688|Vega:OTTMUSG00000009757 +68277 2310057M21Rik MGI:MGI:1915527|Ensembl:ENSMUSG00000040177|Vega:OTTMUSG00000059807 +68278 Ddx39 MGI:MGI:1915528|Ensembl:ENSMUSG00000005481|Vega:OTTMUSG00000026023 +68279 Mcoln2 MGI:MGI:1915529|Ensembl:ENSMUSG00000011008|Vega:OTTMUSG00000035947 +68280 Gm12666 MGI:MGI:3650864 +68281 4930430F08Rik MGI:MGI:1921197|Ensembl:ENSMUSG00000046567 +68283 9530077C05Rik MGI:MGI:1915533|Ensembl:ENSMUSG00000036411|Vega:OTTMUSG00000062376 +68285 C630043F03Rik MGI:MGI:1915535 +68291 Mto1 MGI:MGI:1915541|Ensembl:ENSMUSG00000032342|Vega:OTTMUSG00000019696 +68292 Stt3b MGI:MGI:1915542|Ensembl:ENSMUSG00000032437|Vega:OTTMUSG00000062861 +68294 Mfsd10 MGI:MGI:1915544|Ensembl:ENSMUSG00000001082|Vega:OTTMUSG00000023147 +68295 Aar2 MGI:MGI:1915545|Ensembl:ENSMUSG00000027628|Vega:OTTMUSG00000015877 +68298 Ncapd2 MGI:MGI:1915548|Ensembl:ENSMUSG00000038252|Vega:OTTMUSG00000046177 +68299 Vps53 MGI:MGI:1915549|Ensembl:ENSMUSG00000017288|Vega:OTTMUSG00000006225 +68303 Fam114a1 MGI:MGI:1915553|Ensembl:ENSMUSG00000029185|Vega:OTTMUSG00000023413 +68304 Kdelc2 MGI:MGI:1923765|Ensembl:ENSMUSG00000034487|Vega:OTTMUSG00000063125 +68306 4930565N06Rik MGI:MGI:1915556|Ensembl:ENSMUSG00000084834 +68307 Lrriq4 MGI:MGI:1915557|Ensembl:ENSMUSG00000027703|Vega:OTTMUSG00000022329 +68308 4933406F09Rik MGI:MGI:1918289|Ensembl:ENSMUSG00000090585 +68310 Zmym1 MGI:MGI:1915560|Ensembl:ENSMUSG00000043872|Vega:OTTMUSG00000009317 +68311 Lypd2 MGI:MGI:1915561|Ensembl:ENSMUSG00000022595|Vega:OTTMUSG00000045146 +68312 Gstm7 MGI:MGI:1915562|Ensembl:ENSMUSG00000004035|Vega:OTTMUSG00000007101 +68314 Hnf4aos MGI:MGI:1915564|Ensembl:ENSMUSG00000046840 +68316 Apoo MGI:MGI:1915566|Ensembl:ENSMUSG00000079508|Vega:OTTMUSG00000018120 +68318 Aph1c MGI:MGI:1915568|Ensembl:ENSMUSG00000053040|Vega:OTTMUSG00000036116 +68323 Nudt22 MGI:MGI:1915573|Ensembl:ENSMUSG00000037349|Vega:OTTMUSG00000042499 +68327 Tsr3 MGI:MGI:1915577|Ensembl:ENSMUSG00000015126 +68328 Rab13 MGI:MGI:1927232|Ensembl:ENSMUSG00000027935|Vega:OTTMUSG00000021948 +68332 Sdhaf1 MGI:MGI:1915582|Ensembl:ENSMUSG00000074211|Vega:OTTMUSG00000022883 +68337 Crip2 MGI:MGI:1915587|Ensembl:ENSMUSG00000006356|Vega:OTTMUSG00000052480 +68338 Golt1a MGI:MGI:1915588|Ensembl:ENSMUSG00000098306|Ensembl:ENSMUSG00000103421|Vega:OTTMUSG00000044879|Vega:OTTMUSG00000044884 +68339 Ccdc88c MGI:MGI:1915589|Ensembl:ENSMUSG00000021182 +68342 Ndufb10 MGI:MGI:1915592|Ensembl:ENSMUSG00000040048|Vega:OTTMUSG00000029227 +68344 Tmem174 MGI:MGI:1915594|Ensembl:ENSMUSG00000046082 +68346 Sirt5 MGI:MGI:1915596|Ensembl:ENSMUSG00000054021 +68347 Mettl26 MGI:MGI:1915597|Ensembl:ENSMUSG00000025731|Vega:OTTMUSG00000035873 +68348 Serpina1f MGI:MGI:1915598|Ensembl:ENSMUSG00000021081|Vega:OTTMUSG00000027644 +68349 Ndufs3 MGI:MGI:1915599|Ensembl:ENSMUSG00000005510|Vega:OTTMUSG00000014317 +68350 Mul1 MGI:MGI:1915600|Ensembl:ENSMUSG00000041241|Vega:OTTMUSG00000010003 +68352 Aspdh MGI:MGI:1915602|Ensembl:ENSMUSG00000038704|Vega:OTTMUSG00000029000 +68354 Plekhd1os MGI:MGI:1915604 +68355 2010204K13Rik MGI:MGI:1922859 +68364 0610030E20Rik MGI:MGI:1915614|Ensembl:ENSMUSG00000058706|Vega:OTTMUSG00000057921 +68365 Rab14 MGI:MGI:1915615|Ensembl:ENSMUSG00000026878|Vega:OTTMUSG00000012919 +68366 Tmem129 MGI:MGI:1915616|Ensembl:ENSMUSG00000019295|Vega:OTTMUSG00000025080 +68369 0610031O16Rik MGI:MGI:1915619|Ensembl:ENSMUSG00000099146 +68371 Pbld1 MGI:MGI:1915621|Ensembl:ENSMUSG00000112129 +68373 Gssos1 MGI:MGI:1915623 +68375 Ndufa8 MGI:MGI:1915625|Ensembl:ENSMUSG00000026895|Vega:OTTMUSG00000012097 +68376 0610040A22Rik MGI:MGI:1915626 +68379 Ciz1 MGI:MGI:1920234|Ensembl:ENSMUSG00000039205|Vega:OTTMUSG00000012950 +68380 0610042G04Rik MGI:MGI:1915630 +68385 Tlcd1 MGI:MGI:1915572|Ensembl:ENSMUSG00000019437|Vega:OTTMUSG00000000096 +68386 0610039K10Rik MGI:MGI:1915636|Ensembl:ENSMUSG00000058812 +68393 Mogat1 MGI:MGI:1915643|Ensembl:ENSMUSG00000012187|Vega:OTTMUSG00000022263 +68394 Ccdc163 MGI:MGI:1915644|Ensembl:ENSMUSG00000028689|Vega:OTTMUSG00000009569 +68395 LOC68395 - +68396 Nat8 MGI:MGI:1915646|Ensembl:ENSMUSG00000030004|Vega:OTTMUSG00000034547 +68397 0610039H22Rik MGI:MGI:1915647 +68400 0610043K17Rik MGI:MGI:1915650|Ensembl:ENSMUSG00000087361 +68401 G6pc3 MGI:MGI:1915651|Ensembl:ENSMUSG00000034793|Vega:OTTMUSG00000002495 +68402 0710001A04Rik MGI:MGI:1915652 +68404 Nrn1 MGI:MGI:1915654|Ensembl:ENSMUSG00000039114|Vega:OTTMUSG00000027720 +68409 0710007G10Rik MGI:MGI:1915659 +68414 0710001L09Rik MGI:MGI:1915664 +68416 Sycn MGI:MGI:1915666|Ensembl:ENSMUSG00000084174|Vega:OTTMUSG00000059062 +68420 Ankrd13a MGI:MGI:1915670|Ensembl:ENSMUSG00000041870|Vega:OTTMUSG00000014590 +68421 Lmbrd1 MGI:MGI:1915671|Ensembl:ENSMUSG00000073725|Vega:OTTMUSG00000046322 +68423 Ankrd13d MGI:MGI:1915673|Ensembl:ENSMUSG00000005986|Vega:OTTMUSG00000036701 +68427 Slc39a13 MGI:MGI:1915677|Ensembl:ENSMUSG00000002105|Vega:OTTMUSG00000014353 +68428 Steap3 MGI:MGI:1915678|Ensembl:ENSMUSG00000026389|Vega:OTTMUSG00000021495 +68431 Fbxl15 MGI:MGI:1915681|Ensembl:ENSMUSG00000025226 +68433 1010001I08Rik MGI:MGI:1915683 +68434 1010001N08Rik MGI:MGI:1915684|Ensembl:ENSMUSG00000097222 +68436 Rpl34 MGI:MGI:1915686|Ensembl:ENSMUSG00000062006|Vega:OTTMUSG00000023379 +68437 1200009P19Rik MGI:MGI:1915687 +68440 Dusp23 MGI:MGI:1915690|Ensembl:ENSMUSG00000026544|Vega:OTTMUSG00000050155 +68441 Rraga MGI:MGI:1915691|Ensembl:ENSMUSG00000070934|Vega:OTTMUSG00000007449 +68444 Cyp2d13 MGI:MGI:88605 +68449 Tbc1d10b MGI:MGI:1915699|Ensembl:ENSMUSG00000042492|Vega:OTTMUSG00000029407 +68452 1110001M07Rik MGI:MGI:1915702 +68453 Gpihbp1 MGI:MGI:1915703|Ensembl:ENSMUSG00000022579|Vega:OTTMUSG00000045187 +68458 Ppp1r14a MGI:MGI:1931139|Ensembl:ENSMUSG00000037166|Vega:OTTMUSG00000059218 +68460 Dhrs7c MGI:MGI:1915710|Ensembl:ENSMUSG00000033044|Vega:OTTMUSG00000005932 +68463 Mrpl14 MGI:MGI:1333864|Ensembl:ENSMUSG00000023939|Vega:OTTMUSG00000031351 +68464 1110004M10Rik MGI:MGI:1915714 +68465 Adipor2 MGI:MGI:93830|Ensembl:ENSMUSG00000030168|Vega:OTTMUSG00000049368 +68466 1110003F02Rik MGI:MGI:1915716 +68468 Ly6g6c MGI:MGI:2148930|Ensembl:ENSMUSG00000092586|Vega:OTTMUSG00000037159 +68469 Sox6os MGI:MGI:1915719 +68472 Tmem126b MGI:MGI:1915722|Ensembl:ENSMUSG00000030614|Vega:OTTMUSG00000031626 +68473 Mob1b MGI:MGI:1915723|Ensembl:ENSMUSG00000006262|Vega:OTTMUSG00000025213 +68475 Ssna1 MGI:MGI:1915725|Ensembl:ENSMUSG00000026966|Vega:OTTMUSG00000011901 +68476 1110003F10Rik MGI:MGI:1915726 +68477 Rmnd5a MGI:MGI:1915727|Ensembl:ENSMUSG00000002222|Vega:OTTMUSG00000023427 +68479 Phf5a MGI:MGI:2156864|Ensembl:ENSMUSG00000061360|Vega:OTTMUSG00000034901 +68480 Card19 MGI:MGI:1915730|Ensembl:ENSMUSG00000037960 +68481 Mpzl1 MGI:MGI:1915731|Ensembl:ENSMUSG00000026566|Vega:OTTMUSG00000049918 +68482 1110007E10Rik MGI:MGI:1915732 +68483 1110002O04Rik MGI:MGI:1915733 +68484 Krtap6-5 MGI:MGI:1915734|Ensembl:ENSMUSG00000062400 +68487 Tmem140 MGI:MGI:1915737|Ensembl:ENSMUSG00000057137|Vega:OTTMUSG00000022811 +68488 1110002J07Rik MGI:MGI:1915738 +68490 Zfp579 MGI:MGI:1915740|Ensembl:ENSMUSG00000051550|Vega:OTTMUSG00000033386 +68493 Ndufaf4 MGI:MGI:1915743|Ensembl:ENSMUSG00000028261|Vega:OTTMUSG00000004822 +68497 Arel1 MGI:MGI:1915747|Ensembl:ENSMUSG00000042350|Vega:OTTMUSG00000035485 +68498 Tspan11 MGI:MGI:1915748|Ensembl:ENSMUSG00000030351|Vega:OTTMUSG00000027066 +68499 Mrpl53 MGI:MGI:1915749|Ensembl:ENSMUSG00000030037|Vega:OTTMUSG00000057884 +68500 1110008E08Rik MGI:MGI:1915750 +68501 Nsmce2 MGI:MGI:1915751|Ensembl:ENSMUSG00000059586 +68505 Vps51 MGI:MGI:1915755|Ensembl:ENSMUSG00000024797|Vega:OTTMUSG00000028979 +68507 Ppfia4 MGI:MGI:1915757|Ensembl:ENSMUSG00000026458|Vega:OTTMUSG00000049678 +68509 Ptx4 MGI:MGI:1915759|Ensembl:ENSMUSG00000044172 +68510 Ints1 MGI:MGI:1915760|Ensembl:ENSMUSG00000029547|Vega:OTTMUSG00000054802 +68511 Dcdc2c MGI:MGI:1915761|Ensembl:ENSMUSG00000020633|Vega:OTTMUSG00000048284 +68512 Tomm5 MGI:MGI:1915762|Ensembl:ENSMUSG00000078713|Vega:OTTMUSG00000007500 +68514 Micu2 MGI:MGI:1915764|Ensembl:ENSMUSG00000021973 +68515 Myadml2 MGI:MGI:1915765|Ensembl:ENSMUSG00000025141|Vega:OTTMUSG00000004089 +68519 Eml1 MGI:MGI:1915769|Ensembl:ENSMUSG00000058070|Vega:OTTMUSG00000024650 +68520 Zfyve21 MGI:MGI:1915770|Ensembl:ENSMUSG00000021286 +68521 Fam189b MGI:MGI:1915771|Ensembl:ENSMUSG00000032657|Vega:OTTMUSG00000029747 +68522 1110013H19Rik MGI:MGI:1915772 +68523 Fam96b MGI:MGI:1915773|Ensembl:ENSMUSG00000031879|Vega:OTTMUSG00000035461 +68524 Wipf2 MGI:MGI:1924462|Ensembl:ENSMUSG00000038013|Vega:OTTMUSG00000006444 +68525 Evc2 MGI:MGI:1915775|Ensembl:ENSMUSG00000050248|Vega:OTTMUSG00000025801 +68526 Gpr155 MGI:MGI:1915776|Ensembl:ENSMUSG00000041762|Vega:OTTMUSG00000013435 +68527 Ucma MGI:MGI:1915777|Ensembl:ENSMUSG00000026668|Vega:OTTMUSG00000010819 +68528 Smim6 MGI:MGI:1915778|Ensembl:ENSMUSG00000075420|Vega:OTTMUSG00000003652 +68529 1110019B22Rik MGI:MGI:1915779 +68531 1110020A21Rik MGI:MGI:1915781|Ensembl:ENSMUSG00000097047 +68533 Mphosph6 MGI:MGI:1915783|Ensembl:ENSMUSG00000031843|Vega:OTTMUSG00000061616 +68537 Mrpl13 MGI:MGI:2137218|Ensembl:ENSMUSG00000022370|Vega:OTTMUSG00000035622 +68539 Tmem109 MGI:MGI:1915789|Ensembl:ENSMUSG00000034659|Vega:OTTMUSG00000033009 +68544 Trir MGI:MGI:1922833|Ensembl:ENSMUSG00000041203|Vega:OTTMUSG00000061401 +68545 Ecscr MGI:MGI:1915795|Ensembl:ENSMUSG00000073599|Vega:OTTMUSG00000033150 +68549 Sgo2a MGI:MGI:1098767|Ensembl:ENSMUSG00000026039|Vega:OTTMUSG00000021832 +68550 Tefm MGI:MGI:1915800|Ensembl:ENSMUSG00000046909|Vega:OTTMUSG00000000215 +68552 Smim14 MGI:MGI:1915802|Ensembl:ENSMUSG00000037822|Vega:OTTMUSG00000055459 +68553 Col6a4 MGI:MGI:1915803|Ensembl:ENSMUSG00000032572|Vega:OTTMUSG00000032575 +68554 Cebpzos MGI:MGI:1915804|Ensembl:ENSMUSG00000062691|Vega:OTTMUSG00000050998 +68556 Uckl1 MGI:MGI:1915806|Ensembl:ENSMUSG00000089917|Vega:OTTMUSG00000016737 +68558 Ankra2 MGI:MGI:1915808|Ensembl:ENSMUSG00000021661|Vega:OTTMUSG00000032623 +68559 Pdrg1 MGI:MGI:1915809|Ensembl:ENSMUSG00000027472|Vega:OTTMUSG00000015778 +68563 Dpm3 MGI:MGI:1915813|Ensembl:ENSMUSG00000042737|Vega:OTTMUSG00000022265 +68564 Nufip2 MGI:MGI:1915814|Ensembl:ENSMUSG00000037857|Vega:OTTMUSG00000008179 +68565 Mrps18a MGI:MGI:1915815|Ensembl:ENSMUSG00000023967|Vega:OTTMUSG00000028345 +68566 Caly MGI:MGI:1915816|Ensembl:ENSMUSG00000025468|Vega:OTTMUSG00000060573 +68567 Cgref1 MGI:MGI:1915817|Ensembl:ENSMUSG00000029161|Vega:OTTMUSG00000055053 +68572 Mrpl58 MGI:MGI:1915822|Ensembl:ENSMUSG00000018858|Vega:OTTMUSG00000003439 +68576 Lamtor5 MGI:MGI:1915826|Ensembl:ENSMUSG00000087260 +68581 Tmed10 MGI:MGI:1915831|Ensembl:ENSMUSG00000021248 +68584 1110020C17Rik MGI:MGI:1915834 +68585 Rtn4 MGI:MGI:1915835|Ensembl:ENSMUSG00000020458|Vega:OTTMUSG00000005336 +68588 Cthrc1 MGI:MGI:1915838|Ensembl:ENSMUSG00000054196|Vega:OTTMUSG00000028035 +68591 Mocos MGI:MGI:1915841|Ensembl:ENSMUSG00000039616 +68592 Syf2 MGI:MGI:1915842|Ensembl:ENSMUSG00000028821|Vega:OTTMUSG00000011091 +68594 1110018F16Rik MGI:MGI:1915844 +68597 Ccdc167 MGI:MGI:1915847|Ensembl:ENSMUSG00000024018|Vega:OTTMUSG00000033064 +68598 Dnajc8 MGI:MGI:1915848|Ensembl:ENSMUSG00000054405|Vega:OTTMUSG00000009788 +68600 1110021P09Rik MGI:MGI:1915850 +68603 Pmvk MGI:MGI:1915853|Ensembl:ENSMUSG00000027952|Vega:OTTMUSG00000022076 +68606 Ppm1f MGI:MGI:1918464|Ensembl:ENSMUSG00000026181|Vega:OTTMUSG00000023702 +68607 Serhl MGI:MGI:1890404|Ensembl:ENSMUSG00000058586|Vega:OTTMUSG00000035724 +68611 Mrpl28 MGI:MGI:1915861|Ensembl:ENSMUSG00000024181|Vega:OTTMUSG00000026501 +68612 Ube2c MGI:MGI:1915862|Ensembl:ENSMUSG00000001403|Vega:OTTMUSG00000001153 +68614 Letmd1 MGI:MGI:1915864|Ensembl:ENSMUSG00000037353 +68616 Gdpd3 MGI:MGI:1915866|Ensembl:ENSMUSG00000030703|Vega:OTTMUSG00000058353 +68617 Mtcl1 MGI:MGI:1915867|Ensembl:ENSMUSG00000052105|Vega:OTTMUSG00000033967 +68618 1110012L19Rik MGI:MGI:1915868|Ensembl:ENSMUSG00000045237|Vega:OTTMUSG00000017762 +68625 Cfap57 MGI:MGI:2686209|Ensembl:ENSMUSG00000028730|Vega:OTTMUSG00000008826 +68626 Elac2 MGI:MGI:1890496|Ensembl:ENSMUSG00000020549|Vega:OTTMUSG00000005902 +68628 Fbxw9 MGI:MGI:1915878|Ensembl:ENSMUSG00000008167|Vega:OTTMUSG00000031479 +68629 1110013I04Rik MGI:MGI:1915879 +68631 Cryl1 MGI:MGI:1915881|Ensembl:ENSMUSG00000021947 +68632 Myct1 MGI:MGI:1915882|Ensembl:ENSMUSG00000046916|Vega:OTTMUSG00000063562 +68634 Tm2d3 MGI:MGI:1915884|Ensembl:ENSMUSG00000078681|Vega:OTTMUSG00000024931 +68635 1110025M09Rik MGI:MGI:1915885 +68636 Fahd1 MGI:MGI:1915886|Ensembl:ENSMUSG00000045316 +68637 1110025L11Rik MGI:MGI:1915887|Ensembl:ENSMUSG00000068073|Vega:OTTMUSG00000044902 +68642 Tmem216 MGI:MGI:1920020|Ensembl:ENSMUSG00000024667|Vega:OTTMUSG00000033090 +68644 Abhd14a MGI:MGI:1915894|Ensembl:ENSMUSG00000042210|Vega:OTTMUSG00000049587 +68646 Nadk2 MGI:MGI:1915896|Ensembl:ENSMUSG00000022253 +68652 Tab2 MGI:MGI:1915902|Ensembl:ENSMUSG00000015755|Vega:OTTMUSG00000034128 +68653 Samm50 MGI:MGI:1915903|Ensembl:ENSMUSG00000022437 +68655 Fndc1 MGI:MGI:1915905|Ensembl:ENSMUSG00000071984|Vega:OTTMUSG00000035277 +68659 Fam198b MGI:MGI:1915909|Ensembl:ENSMUSG00000027955|Vega:OTTMUSG00000026688 +68662 Scgb3a1 MGI:MGI:1915912|Ensembl:ENSMUSG00000064057|Vega:OTTMUSG00000005564 +68666 Svop MGI:MGI:1915916|Ensembl:ENSMUSG00000042078|Vega:OTTMUSG00000030561 +68667 Trpm4 MGI:MGI:1915917|Ensembl:ENSMUSG00000038260|Vega:OTTMUSG00000058654 +68668 Klk5 MGI:MGI:1915918|Ensembl:ENSMUSG00000074155|Vega:OTTMUSG00000027222 +68671 Pcyt2 MGI:MGI:1915921|Ensembl:ENSMUSG00000025137|Vega:OTTMUSG00000004081 +68672 1110035E04Rik MGI:MGI:1915922 +68673 Krtap4-2 MGI:MGI:1915923|Ensembl:ENSMUSG00000044649|Vega:OTTMUSG00000002185 +68675 Fam172a MGI:MGI:1915925|Ensembl:ENSMUSG00000064138 +68678 Smtnl1 MGI:MGI:1915928|Ensembl:ENSMUSG00000027077|Vega:OTTMUSG00000013726 +68680 Fitm1 MGI:MGI:1915930|Ensembl:ENSMUSG00000022215|Vega:OTTMUSG00000041996 +68682 Slc44a2 MGI:MGI:1915932|Ensembl:ENSMUSG00000057193|Vega:OTTMUSG00000063301 +68684 1110035D15Rik MGI:MGI:1915934 +68686 1110035H17Rik MGI:MGI:1915936 +68690 1110028F11Rik MGI:MGI:1915940 +68691 Kansl1l MGI:MGI:1915941|Ensembl:ENSMUSG00000026004|Vega:OTTMUSG00000025009 +68692 1110028F18Rik MGI:MGI:1915942|Ensembl:ENSMUSG00000099139 +68693 Hnrnpul2 MGI:MGI:1915943|Ensembl:ENSMUSG00000071659 +68694 Lce1e MGI:MGI:1915944|Ensembl:ENSMUSG00000068889|Vega:OTTMUSG00000051853 +68695 Hddc3 MGI:MGI:1915945|Ensembl:ENSMUSG00000030532|Vega:OTTMUSG00000058663 +68697 1110036E04Rik MGI:MGI:1915947|Ensembl:ENSMUSG00000097036 +68701 Ppp1r27 MGI:MGI:1915951|Ensembl:ENSMUSG00000025129|Vega:OTTMUSG00000004090 +68703 Rere MGI:MGI:2683486|Ensembl:ENSMUSG00000039852|Vega:OTTMUSG00000010393 +68705 Gtf2f2 MGI:MGI:1915955|Ensembl:ENSMUSG00000067995 +68708 Rabl2 MGI:MGI:1915958|Ensembl:ENSMUSG00000022621|Vega:OTTMUSG00000035204 +68709 Cilp2 MGI:MGI:1915959|Ensembl:ENSMUSG00000044006|Vega:OTTMUSG00000033966 +68713 Ifitm1 MGI:MGI:1915963|Ensembl:ENSMUSG00000025491|Vega:OTTMUSG00000021113 +68718 Rnf166 MGI:MGI:1915968|Ensembl:ENSMUSG00000014470|Vega:OTTMUSG00000030756 +68720 Lce1b MGI:MGI:1915970|Ensembl:ENSMUSG00000027923|Vega:OTTMUSG00000051847 +68721 1110032A03Rik MGI:MGI:1915971|Ensembl:ENSMUSG00000037971|Vega:OTTMUSG00000042097 +68723 Hrnr MGI:MGI:3046938|Ensembl:ENSMUSG00000041991|Vega:OTTMUSG00000023810 +68724 Arl8a MGI:MGI:1915974|Ensembl:ENSMUSG00000026426|Vega:OTTMUSG00000021955 +68725 1110032F04Rik MGI:MGI:1915975|Ensembl:ENSMUSG00000046999|Vega:OTTMUSG00000044906 +68727 1110032L06Rik MGI:MGI:1915977 +68728 Trp53inp2 MGI:MGI:1915978|Ensembl:ENSMUSG00000038375|Vega:OTTMUSG00000016061 +68729 Trim37 MGI:MGI:2153072|Ensembl:ENSMUSG00000018548|Vega:OTTMUSG00000001222 +68730 Dus1l MGI:MGI:1915980|Ensembl:ENSMUSG00000025155|Vega:OTTMUSG00000004141 +68731 Rbfa MGI:MGI:1915981|Ensembl:ENSMUSG00000024570 +68732 Carmil1 MGI:MGI:1915982|Ensembl:ENSMUSG00000021338|Vega:OTTMUSG00000000598 +68734 Ppp4r3a MGI:MGI:1915984|Ensembl:ENSMUSG00000041846 +68735 Mrps18c MGI:MGI:1915985|Ensembl:ENSMUSG00000016833|Vega:OTTMUSG00000026194 +68736 Tyw5 MGI:MGI:1915986|Ensembl:ENSMUSG00000048495|Vega:OTTMUSG00000029759 +68737 Angel1 MGI:MGI:1915987|Ensembl:ENSMUSG00000021257|Vega:OTTMUSG00000036635 +68738 Acss1 MGI:MGI:1915988|Ensembl:ENSMUSG00000027452|Vega:OTTMUSG00000015731 +68740 Krtap22-2 MGI:MGI:1915990|Ensembl:ENSMUSG00000095992 +68742 Tmem219 MGI:MGI:1915992|Ensembl:ENSMUSG00000060538|Vega:OTTMUSG00000031957 +68743 Anln MGI:MGI:1920174|Ensembl:ENSMUSG00000036777|Vega:OTTMUSG00000062373 +68744 Zfp740 MGI:MGI:1915994|Ensembl:ENSMUSG00000046897|Vega:OTTMUSG00000030885 +68750 Rreb1 MGI:MGI:2443664|Ensembl:ENSMUSG00000039087|Vega:OTTMUSG00000033132 +68753 Mybphl MGI:MGI:1916003|Ensembl:ENSMUSG00000068745|Vega:OTTMUSG00000007301 +68755 Cgrrf1 MGI:MGI:1916368|Ensembl:ENSMUSG00000055128|Vega:OTTMUSG00000027962 +68758 Abhd11 MGI:MGI:1916008|Ensembl:ENSMUSG00000040532|Vega:OTTMUSG00000025990 +68760 Synpo2l MGI:MGI:1916010|Ensembl:ENSMUSG00000039376|Vega:OTTMUSG00000027061 +68763 1110038B12Rik MGI:MGI:1916013|Ensembl:ENSMUSG00000092203 +68764 Cdhr3 MGI:MGI:1916014|Ensembl:ENSMUSG00000035860 +68767 Washc1 MGI:MGI:1916017|Ensembl:ENSMUSG00000024101 +68768 Krtap4-6 MGI:MGI:1916018|Ensembl:ENSMUSG00000075566|Vega:OTTMUSG00000002179 +68770 Phtf2 MGI:MGI:1916020|Ensembl:ENSMUSG00000039987|Vega:OTTMUSG00000029591 +68771 1110058D11Rik MGI:MGI:1916021 +68774 Ms4a6d MGI:MGI:1916024|Ensembl:ENSMUSG00000024679|Vega:OTTMUSG00000033443 +68775 Atp6v1c2 MGI:MGI:1916025|Ensembl:ENSMUSG00000020566|Vega:OTTMUSG00000023819 +68776 Taf11 MGI:MGI:1916026|Ensembl:ENSMUSG00000024218|Vega:OTTMUSG00000024178 +68777 Tmem53 MGI:MGI:1916027|Ensembl:ENSMUSG00000048772|Vega:OTTMUSG00000009944 +68778 Gucd1 MGI:MGI:1916028|Ensembl:ENSMUSG00000033416|Vega:OTTMUSG00000031798 +68781 1110055C04Rik MGI:MGI:1916031 +68786 1110059G02Rik MGI:MGI:1916036 +68789 Trmt61b MGI:MGI:1916039|Ensembl:ENSMUSG00000085492 +68790 Fendrr MGI:MGI:1916040|Ensembl:ENSMUSG00000097336 +68791 1110050P16Rik MGI:MGI:1916041 +68792 Srpx2 MGI:MGI:1916042|Ensembl:ENSMUSG00000031253|Vega:OTTMUSG00000018714 +68794 Flnc MGI:MGI:95557|Ensembl:ENSMUSG00000068699|Vega:OTTMUSG00000022425 +68795 Ubr3 MGI:MGI:1861100|Ensembl:ENSMUSG00000044308|Vega:OTTMUSG00000013114 +68796 Tmem214 MGI:MGI:1916046|Ensembl:ENSMUSG00000038828|Vega:OTTMUSG00000022318 +68797 Pdgfrl MGI:MGI:1916047|Ensembl:ENSMUSG00000031595|Vega:OTTMUSG00000031636 +68799 Rgmb MGI:MGI:1916049|Ensembl:ENSMUSG00000048027 +68800 Prr32 MGI:MGI:1916050|Ensembl:ENSMUSG00000037086|Vega:OTTMUSG00000017420 +68801 Elovl5 MGI:MGI:1916051|Ensembl:ENSMUSG00000032349|Vega:OTTMUSG00000022986 +68802 Mypn MGI:MGI:1916052|Ensembl:ENSMUSG00000020067 +68808 1110046J04Rik MGI:MGI:1916058|Ensembl:ENSMUSG00000085457 +68810 Nexn MGI:MGI:1916060|Ensembl:ENSMUSG00000039103|Vega:OTTMUSG00000053742 +68813 Dock5 MGI:MGI:2652871|Ensembl:ENSMUSG00000044447 +68814 1110060G06Rik MGI:MGI:1916064 +68815 Btbd10 MGI:MGI:1916065|Ensembl:ENSMUSG00000038187|Vega:OTTMUSG00000028648 +68816 Ppil1 MGI:MGI:1916066|Ensembl:ENSMUSG00000024007|Vega:OTTMUSG00000028958 +68817 Ddi2 MGI:MGI:1917244|Ensembl:ENSMUSG00000078515|Vega:OTTMUSG00000010364 +68818 Zfand2b MGI:MGI:1916068|Ensembl:ENSMUSG00000026197|Vega:OTTMUSG00000034818 +68828 Sync MGI:MGI:1916078|Ensembl:ENSMUSG00000001333|Vega:OTTMUSG00000009627 +68832 Ldah MGI:MGI:1916082|Ensembl:ENSMUSG00000037669 +68833 Pdcl3 MGI:MGI:1916083|Ensembl:ENSMUSG00000026078|Vega:OTTMUSG00000050275 +68836 Mrpl52 MGI:MGI:1916086|Ensembl:ENSMUSG00000010406|Vega:OTTMUSG00000053899 +68837 Foxk2 MGI:MGI:1916087|Ensembl:ENSMUSG00000039275|Vega:OTTMUSG00000004287 +68839 Ankrd46 MGI:MGI:1916089|Ensembl:ENSMUSG00000048307 +68841 Lppos MGI:MGI:1916091 +68842 Tulp4 MGI:MGI:1916092|Ensembl:ENSMUSG00000034377|Vega:OTTMUSG00000024073 +68844 1110057P08Rik MGI:MGI:1916094|Ensembl:ENSMUSG00000068067|Vega:OTTMUSG00000044908 +68845 Pih1d1 MGI:MGI:1916095|Ensembl:ENSMUSG00000003423|Vega:OTTMUSG00000023494 +68846 Rnf208 MGI:MGI:1916096|Ensembl:ENSMUSG00000044628|Vega:OTTMUSG00000011889 +68852 Lrrn4cl MGI:MGI:1916102|Ensembl:ENSMUSG00000071656 +68854 Asb11 MGI:MGI:1916104|Ensembl:ENSMUSG00000031382|Vega:OTTMUSG00000019517 +68857 Dtwd2 MGI:MGI:1916107|Ensembl:ENSMUSG00000024505|Vega:OTTMUSG00000033142 +68859 Smim1 MGI:MGI:1916109|Ensembl:ENSMUSG00000078350|Vega:OTTMUSG00000010499 +68861 1190002N15Rik MGI:MGI:1916111|Ensembl:ENSMUSG00000045414|Vega:OTTMUSG00000046987 +68865 Arv1 MGI:MGI:1916115|Ensembl:ENSMUSG00000031982|Vega:OTTMUSG00000061564 +68867 Rnf122 MGI:MGI:1916117|Ensembl:ENSMUSG00000039328|Vega:OTTMUSG00000027149 +68870 Ak8 MGI:MGI:1916120|Ensembl:ENSMUSG00000026807|Vega:OTTMUSG00000011768 +68874 Klhdc9 MGI:MGI:1916124|Ensembl:ENSMUSG00000045259|Vega:OTTMUSG00000021557 +68875 Tmcc2 MGI:MGI:1916125|Ensembl:ENSMUSG00000042066|Vega:OTTMUSG00000026803 +68876 Atp23 MGI:MGI:1916984|Ensembl:ENSMUSG00000025436 +68877 Maf1 MGI:MGI:1916127|Ensembl:ENSMUSG00000022553|Vega:OTTMUSG00000034711 +68879 Prpf6 MGI:MGI:1922946|Ensembl:ENSMUSG00000002455|Vega:OTTMUSG00000016808 +68880 Fam240b MGI:MGI:1916130|Ensembl:ENSMUSG00000096537|Vega:OTTMUSG00000044950 +68888 Gkn3 MGI:MGI:1916138|Ensembl:ENSMUSG00000030048|Vega:OTTMUSG00000024192 +68889 Ubac2 MGI:MGI:1916139|Ensembl:ENSMUSG00000041765 +68891 Cd177 MGI:MGI:1916141|Ensembl:ENSMUSG00000052212|Vega:OTTMUSG00000058235 +68893 1110064A23Rik MGI:MGI:1916143 +68895 Rasl11a MGI:MGI:1916145|Ensembl:ENSMUSG00000029641|Vega:OTTMUSG00000055182 +68897 Disp1 MGI:MGI:1916147|Ensembl:ENSMUSG00000030768|Vega:OTTMUSG00000050524 +68904 Abhd13 MGI:MGI:1916154|Ensembl:ENSMUSG00000040396|Vega:OTTMUSG00000032894 +68905 1110065H08Rik MGI:MGI:1916155 +68910 Zfp467 MGI:MGI:1916160|Ensembl:ENSMUSG00000068551|Vega:OTTMUSG00000022129 +68911 Pygo2 MGI:MGI:1916161|Ensembl:ENSMUSG00000047824|Vega:OTTMUSG00000022069 +68915 Vars2 MGI:MGI:1916165|Ensembl:ENSMUSG00000038838|Vega:OTTMUSG00000036770 +68916 Cdkal1 MGI:MGI:1921765|Ensembl:ENSMUSG00000006191|Vega:OTTMUSG00000000663 +68917 Hint2 MGI:MGI:1916167|Ensembl:ENSMUSG00000028470|Vega:OTTMUSG00000007051 +68918 1190005I06Rik MGI:MGI:1916168|Ensembl:ENSMUSG00000043687|Vega:OTTMUSG00000032887 +68920 1110065P20Rik MGI:MGI:1916170|Ensembl:ENSMUSG00000078570|Vega:OTTMUSG00000009174 +68922 Dnaic1 MGI:MGI:1916172|Ensembl:ENSMUSG00000061322|Vega:OTTMUSG00000006654 +68923 1190001L17Rik MGI:MGI:1916173 +68924 1190001M18Rik MGI:MGI:1916174 +68925 Rpap1 MGI:MGI:1916175|Ensembl:ENSMUSG00000034032|Vega:OTTMUSG00000016529 +68926 Ubap2 MGI:MGI:1916176|Ensembl:ENSMUSG00000028433|Vega:OTTMUSG00000006639 +68927 Ptcd2 MGI:MGI:1916177|Ensembl:ENSMUSG00000021650 +68929 Mospd3 MGI:MGI:1916179|Ensembl:ENSMUSG00000037221|Vega:OTTMUSG00000021946 +68936 Smim11 MGI:MGI:1916186|Ensembl:ENSMUSG00000051989|Vega:OTTMUSG00000028548 +68938 Aspscr1 MGI:MGI:1916188|Ensembl:ENSMUSG00000025142|Vega:OTTMUSG00000004078 +68939 Rasl11b MGI:MGI:1916189|Ensembl:ENSMUSG00000049907|Vega:OTTMUSG00000044476 +68941 1110018N20Rik MGI:MGI:1915753 +68942 Chmp2b MGI:MGI:1916192|Ensembl:ENSMUSG00000004843 +68943 Pink1 MGI:MGI:1916193|Ensembl:ENSMUSG00000028756|Vega:OTTMUSG00000009975 +68944 Tmco1 MGI:MGI:1921173|Ensembl:ENSMUSG00000052428|Vega:OTTMUSG00000050635 +68945 1500002J14Rik MGI:MGI:1916195 +68946 1500002C15Rik MGI:MGI:1916196 +68947 Chst8 MGI:MGI:1916197|Ensembl:ENSMUSG00000060402|Vega:OTTMUSG00000029096 +68948 Fam216a MGI:MGI:1916198|Ensembl:ENSMUSG00000029463|Vega:OTTMUSG00000026647 +68949 Zfas1 MGI:MGI:1916199 +68952 Fam57b MGI:MGI:1916202|Ensembl:ENSMUSG00000058966|Vega:OTTMUSG00000058356 +68953 Chmp2a MGI:MGI:1916203|Ensembl:ENSMUSG00000033916|Vega:OTTMUSG00000060980 +68954 1500012K07Rik MGI:MGI:1916204|Ensembl:ENSMUSG00000097247 +68955 Srrm4 MGI:MGI:1916205|Ensembl:ENSMUSG00000063919|Vega:OTTMUSG00000014692 +68956 1500006G06Rik MGI:MGI:1916206 +68957 Paqr6 MGI:MGI:1916207|Ensembl:ENSMUSG00000041423|Vega:OTTMUSG00000032750 +68961 Phkg2 MGI:MGI:1916211|Ensembl:ENSMUSG00000030815|Vega:OTTMUSG00000026244 +68964 Ctc1 MGI:MGI:1916214|Ensembl:ENSMUSG00000020898|Vega:OTTMUSG00000005957 +68966 Ngdn MGI:MGI:1916216|Ensembl:ENSMUSG00000022204 +68968 Cdan1 MGI:MGI:1916218|Ensembl:ENSMUSG00000027284|Vega:OTTMUSG00000015621 +68969 Eif1b MGI:MGI:1916219|Ensembl:ENSMUSG00000006941|Vega:OTTMUSG00000062583 +68970 Dcaf12 MGI:MGI:1916220|Ensembl:ENSMUSG00000028436|Vega:OTTMUSG00000006637 +68971 Tamm41 MGI:MGI:1916221|Ensembl:ENSMUSG00000030316|Vega:OTTMUSG00000024034 +68972 Tatdn3 MGI:MGI:1916222|Ensembl:ENSMUSG00000026632|Vega:OTTMUSG00000021552 +68975 Med27 MGI:MGI:1916225|Ensembl:ENSMUSG00000026799|Vega:OTTMUSG00000011597 +68977 Haghl MGI:MGI:1919877|Ensembl:ENSMUSG00000061046|Vega:OTTMUSG00000033886 +68978 1500002I01Rik MGI:MGI:1916228 +68979 Nol11 MGI:MGI:1916229|Ensembl:ENSMUSG00000018433|Vega:OTTMUSG00000003633 +68980 Wdr53 MGI:MGI:1916230|Ensembl:ENSMUSG00000022787|Vega:OTTMUSG00000025767 +68981 Snrpa1 MGI:MGI:1916231|Ensembl:ENSMUSG00000030512|Vega:OTTMUSG00000024902 +68982 1500015A07Rik MGI:MGI:1916232|Ensembl:ENSMUSG00000098702 +68986 Gad1os MGI:MGI:1916236|Ensembl:ENSMUSG00000087264 +68988 Prpf31 MGI:MGI:1916238|Ensembl:ENSMUSG00000008373|Vega:OTTMUSG00000023399 +68991 Ssu72 MGI:MGI:1916241|Ensembl:ENSMUSG00000029038|Vega:OTTMUSG00000010846 +68992 Zfp580 MGI:MGI:1916242|Ensembl:ENSMUSG00000055633|Vega:OTTMUSG00000058596 +68994 1500015L24Rik MGI:MGI:1916244|Ensembl:ENSMUSG00000094732 +68995 Mcts1 MGI:MGI:1916245|Ensembl:ENSMUSG00000000355|Vega:OTTMUSG00000017243 +68999 Anapc10 MGI:MGI:1916249|Ensembl:ENSMUSG00000036977|Vega:OTTMUSG00000061320 +69002 1500026H17Rik MGI:MGI:1916252|Ensembl:ENSMUSG00000097383 +69004 6330418K02Rik MGI:MGI:3697416|Ensembl:ENSMUSG00000085227 +69008 Cab39l MGI:MGI:1914081|Ensembl:ENSMUSG00000021981 +69009 Thap7 MGI:MGI:1916259|Ensembl:ENSMUSG00000022760|Vega:OTTMUSG00000025193 +69010 Anapc13 MGI:MGI:1916260|Ensembl:ENSMUSG00000035048|Vega:OTTMUSG00000048442 +69017 Prrt2 MGI:MGI:1916267|Ensembl:ENSMUSG00000045114|Vega:OTTMUSG00000033189 +69019 Spcs1 MGI:MGI:1916269|Ensembl:ENSMUSG00000021917|Vega:OTTMUSG00000034302 +69020 Zfp707 MGI:MGI:1916270|Ensembl:ENSMUSG00000034429|Vega:OTTMUSG00000022535 +69024 Snx15 MGI:MGI:1916274|Ensembl:ENSMUSG00000024787|Vega:OTTMUSG00000034056 +69025 1500032P08Rik MGI:MGI:1916275 +69028 Mitd1 MGI:MGI:1916278|Ensembl:ENSMUSG00000026088|Vega:OTTMUSG00000026563 +69029 Smdt1 MGI:MGI:1916279|Ensembl:ENSMUSG00000022452|Vega:OTTMUSG00000034180 +69030 1810006J02Rik MGI:MGI:1916280|Ensembl:ENSMUSG00000100182 +69031 Galnt6os MGI:MGI:1916281 +69032 Lyzl4 MGI:MGI:1916282|Ensembl:ENSMUSG00000032530|Vega:OTTMUSG00000027453 +69034 Nupr1l MGI:MGI:1923099|Ensembl:ENSMUSG00000095789|Vega:OTTMUSG00000047887 +69035 Zdhhc3 MGI:MGI:1926134|Ensembl:ENSMUSG00000025786|Vega:OTTMUSG00000023779 +69036 Zg16 MGI:MGI:1916286|Ensembl:ENSMUSG00000049350|Vega:OTTMUSG00000058493 +69038 Tmem258 MGI:MGI:1916288|Ensembl:ENSMUSG00000036372|Vega:OTTMUSG00000034055 +69042 1810013D15Rik MGI:MGI:1916292|Ensembl:ENSMUSG00000028177 +69044 1810017P11Rik MGI:MGI:1916294 +69046 Isca1 MGI:MGI:1916296|Ensembl:ENSMUSG00000044792|Vega:OTTMUSG00000029126 +69047 Atp2c2 MGI:MGI:1916297|Ensembl:ENSMUSG00000034112|Vega:OTTMUSG00000061644 +69048 Slc30a5 MGI:MGI:1916298|Ensembl:ENSMUSG00000021629 +69049 Nat8f5 MGI:MGI:1916299|Ensembl:ENSMUSG00000079494|Vega:OTTMUSG00000034541 +69050 1810013A23Rik MGI:MGI:1916300|Ensembl:ENSMUSG00000002250 +69051 Pycr2 MGI:MGI:1277956|Ensembl:ENSMUSG00000026520|Vega:OTTMUSG00000050459 +69053 1810013L24Rik MGI:MGI:1916303|Ensembl:ENSMUSG00000022507 +69054 1810007C17Rik MGI:MGI:1916304|Ensembl:ENSMUSG00000100844 +69055 1810007D17Rik MGI:MGI:1916305|Ensembl:ENSMUSG00000100001 +69060 Pnlip MGI:MGI:97722|Ensembl:ENSMUSG00000046008 +69062 1810008B01Rik MGI:MGI:1916312 +69063 1810014P07Rik MGI:MGI:1916313 +69064 Fuom MGI:MGI:1916314|Ensembl:ENSMUSG00000025466|Vega:OTTMUSG00000027343 +69065 Chac1 MGI:MGI:1916315|Ensembl:ENSMUSG00000027313|Vega:OTTMUSG00000015948 +69066 1810010H24Rik MGI:MGI:1916316|Ensembl:ENSMUSG00000078607|Vega:OTTMUSG00000003581 +69068 1810011O10Rik MGI:MGI:1916318|Ensembl:ENSMUSG00000056313|Vega:OTTMUSG00000045584 +69069 1810011H11Rik MGI:MGI:1916319|Ensembl:ENSMUSG00000041707 +69071 Tmem97 MGI:MGI:1916321|Ensembl:ENSMUSG00000037278|Vega:OTTMUSG00000000140 +69072 Ebna1bp2 MGI:MGI:1916322|Ensembl:ENSMUSG00000028729|Vega:OTTMUSG00000008747 +69073 Kdf1 MGI:MGI:1916323|Ensembl:ENSMUSG00000037600|Vega:OTTMUSG00000011152 +69076 Triap1 MGI:MGI:1916326|Ensembl:ENSMUSG00000029535|Vega:OTTMUSG00000014653 +69077 Psmd11 MGI:MGI:1916327|Ensembl:ENSMUSG00000017428|Vega:OTTMUSG00000000212 +69080 Gmppa MGI:MGI:1916330|Ensembl:ENSMUSG00000033021|Vega:OTTMUSG00000019424 +69082 Zc3h15 MGI:MGI:1919747|Ensembl:ENSMUSG00000027091|Vega:OTTMUSG00000013359 +69083 Sult1c2 MGI:MGI:1916333|Ensembl:ENSMUSG00000023122|Vega:OTTMUSG00000028466 +69085 Zcchc9 MGI:MGI:1916335|Ensembl:ENSMUSG00000021621|Vega:OTTMUSG00000042410 +69086 1810019N24Rik MGI:MGI:1916336|Ensembl:ENSMUSG00000097115 +69089 Oxa1l MGI:MGI:1916339|Ensembl:ENSMUSG00000000959|Vega:OTTMUSG00000053878 +69090 Ascc1 MGI:MGI:1916340|Ensembl:ENSMUSG00000044475 +69091 Vps26b MGI:MGI:1917656|Ensembl:ENSMUSG00000031988|Vega:OTTMUSG00000062728 +69094 Tmem160 MGI:MGI:1916344|Ensembl:ENSMUSG00000019158|Vega:OTTMUSG00000060590 +69095 1810012K08Rik MGI:MGI:1916345 +69097 Trim15 MGI:MGI:1916347|Ensembl:ENSMUSG00000050747|Vega:OTTMUSG00000037379 +69099 1810009N02Rik MGI:MGI:1916349 +69101 Ydjc MGI:MGI:1916351|Ensembl:ENSMUSG00000041774|Vega:OTTMUSG00000024793 +69102 1810015C11Rik MGI:MGI:1916352 +69103 1810015A16Rik MGI:MGI:1916353 +69104 March5 MGI:MGI:1915207|Ensembl:ENSMUSG00000023307|Vega:OTTMUSG00000016844 +69106 Stoml1 MGI:MGI:1916356|Ensembl:ENSMUSG00000032333|Vega:OTTMUSG00000063236 +69108 1810012K16Rik MGI:MGI:1916358|Ensembl:ENSMUSG00000099825 +69109 Fam58b MGI:MGI:1916359|Ensembl:ENSMUSG00000049489|Vega:OTTMUSG00000000148 +69113 Alkbh3 MGI:MGI:1916363|Ensembl:ENSMUSG00000040174|Vega:OTTMUSG00000014996 +69116 Ubr4 MGI:MGI:1916366|Ensembl:ENSMUSG00000066036|Vega:OTTMUSG00000009956 +69117 Adh6a MGI:MGI:1916367|Ensembl:ENSMUSG00000053054|Vega:OTTMUSG00000035946 +69120 1810021B22Rik MGI:MGI:1916370|Ensembl:ENSMUSG00000087331 +69121 Chrdl2 MGI:MGI:1916371|Ensembl:ENSMUSG00000030732|Vega:OTTMUSG00000024367 +69123 Eci3 MGI:MGI:1916373|Ensembl:ENSMUSG00000021416|Vega:OTTMUSG00000035929 +69125 Cnot8 MGI:MGI:1916375|Ensembl:ENSMUSG00000020515|Vega:OTTMUSG00000005715 +69126 1810022K09Rik MGI:MGI:1916376|Ensembl:ENSMUSG00000078784|Vega:OTTMUSG00000045900 +69129 Pex11g MGI:MGI:1920905|Ensembl:ENSMUSG00000069633|Vega:OTTMUSG00000030750 +69131 Cdk12 MGI:MGI:1098802|Ensembl:ENSMUSG00000003119|Vega:OTTMUSG00000002637 +69134 Fam25c MGI:MGI:1916384|Ensembl:ENSMUSG00000043681|Vega:OTTMUSG00000033737 +69135 2200001K16Rik MGI:MGI:1916385 +69136 Tusc1 MGI:MGI:2684283|Ensembl:ENSMUSG00000054000|Vega:OTTMUSG00000007809 +69137 Vstm5 MGI:MGI:1916387|Ensembl:ENSMUSG00000031937|Vega:OTTMUSG00000062252 +69139 Ctrcos MGI:MGI:1916389|Ensembl:ENSMUSG00000086818 +69142 Cd209f MGI:MGI:1916392|Ensembl:ENSMUSG00000051906|Vega:OTTMUSG00000033964 +69146 Gsdmd MGI:MGI:1916396|Ensembl:ENSMUSG00000022575 +69147 2200002J24Rik MGI:MGI:1916397|Ensembl:ENSMUSG00000013083 +69149 Kbtbd3 MGI:MGI:1916399|Ensembl:ENSMUSG00000025893|Vega:OTTMUSG00000061684 +69150 Snx4 MGI:MGI:1916400|Ensembl:ENSMUSG00000022808 +69151 Lzic MGI:MGI:1916401|Ensembl:ENSMUSG00000028990|Vega:OTTMUSG00000010270 +69155 1810030O07Rik MGI:MGI:1916405|Ensembl:ENSMUSG00000044148|Vega:OTTMUSG00000016970 +69156 Comtd1 MGI:MGI:1916406|Ensembl:ENSMUSG00000021773|Vega:OTTMUSG00000029118 +69159 Rhebl1 MGI:MGI:1916409|Ensembl:ENSMUSG00000023755|Vega:OTTMUSG00000024109 +69161 Manbal MGI:MGI:1916411|Ensembl:ENSMUSG00000063019|Vega:OTTMUSG00000016164 +69162 Sec31a MGI:MGI:1916412|Ensembl:ENSMUSG00000035325|Vega:OTTMUSG00000043627 +69163 Mrpl44 MGI:MGI:1916413|Ensembl:ENSMUSG00000026248|Vega:OTTMUSG00000047890 +69165 Cd209b MGI:MGI:1916415|Ensembl:ENSMUSG00000065987|Vega:OTTMUSG00000049043 +69166 1810018F18Rik MGI:MGI:1921421|Ensembl:ENSMUSG00000101088 +69168 Bola1 MGI:MGI:1916418|Ensembl:ENSMUSG00000015943|Vega:OTTMUSG00000021905 +69169 Fcmr MGI:MGI:1916419|Ensembl:ENSMUSG00000042474|Vega:OTTMUSG00000026802 +69170 1810026B05Rik MGI:MGI:1916420|Ensembl:ENSMUSG00000101970 +69171 Cnppd1 MGI:MGI:1916421|Ensembl:ENSMUSG00000033159|Vega:OTTMUSG00000048448 +69173 1810037O21Rik MGI:MGI:1916423 +69177 1810027L02Rik MGI:MGI:1916427 +69178 Snx5 MGI:MGI:1916428|Ensembl:ENSMUSG00000027423|Vega:OTTMUSG00000003373 +69179 Tmem110 MGI:MGI:1921500|Ensembl:ENSMUSG00000006526|Vega:OTTMUSG00000035529 +69181 Dyrk2 MGI:MGI:1330301|Ensembl:ENSMUSG00000028630 +69183 C1qtnf2 MGI:MGI:1916433|Ensembl:ENSMUSG00000046491|Vega:OTTMUSG00000005457 +69185 Dtwd1 MGI:MGI:1916435|Ensembl:ENSMUSG00000023330|Vega:OTTMUSG00000015336 +69186 Tmem256 MGI:MGI:1916436|Ensembl:ENSMUSG00000070394|Vega:OTTMUSG00000006000 +69187 Erp27 MGI:MGI:1916437|Ensembl:ENSMUSG00000030219|Vega:OTTMUSG00000034593 +69188 Kmt2e MGI:MGI:1924825|Ensembl:ENSMUSG00000029004|Vega:OTTMUSG00000021312 +69189 Mcemp1 MGI:MGI:1916439|Ensembl:ENSMUSG00000013974|Vega:OTTMUSG00000059170 +69190 Dym MGI:MGI:1918480|Ensembl:ENSMUSG00000035765 +69191 Pdia2 MGI:MGI:1916441|Ensembl:ENSMUSG00000024184|Vega:OTTMUSG00000026504 +69192 Dhx16 MGI:MGI:1916442|Ensembl:ENSMUSG00000024422|Vega:OTTMUSG00000037409 +69193 Platr10 MGI:MGI:1916443|Ensembl:ENSMUSG00000099370 +69194 2010015B12Rik MGI:MGI:1916444 +69195 Tmem121 MGI:MGI:1916445|Ensembl:ENSMUSG00000049036|Vega:OTTMUSG00000052485 +69198 2610024L02Rik MGI:MGI:1916448 +69202 Ptms MGI:MGI:1916452|Ensembl:ENSMUSG00000030122|Vega:OTTMUSG00000024455 +69206 2010016I18Rik MGI:MGI:1916456|Ensembl:ENSMUSG00000091575 +69207 Srsf11 MGI:MGI:1916457|Ensembl:ENSMUSG00000055436|Vega:OTTMUSG00000031923 +69209 2610024J18Rik MGI:MGI:1916459 +69211 2310081J21Rik MGI:MGI:1916461 +69214 2610021J01Rik MGI:MGI:1916464 +69215 Sat2 MGI:MGI:1916465|Ensembl:ENSMUSG00000069835|Vega:OTTMUSG00000006006 +69216 Svbp MGI:MGI:1916466|Ensembl:ENSMUSG00000028643|Vega:OTTMUSG00000008918 +69217 Plekha4 MGI:MGI:1916467|Ensembl:ENSMUSG00000040428|Vega:OTTMUSG00000029145 +69219 Ddah1 MGI:MGI:1916469|Ensembl:ENSMUSG00000028194|Vega:OTTMUSG00000029461 +69221 2410006H16Rik MGI:MGI:1916471|Ensembl:ENSMUSG00000086841 +69225 Naxd MGI:MGI:1913353|Ensembl:ENSMUSG00000031505|Vega:OTTMUSG00000042282 +69226 Snx24 MGI:MGI:1916476|Ensembl:ENSMUSG00000024535 +69227 Selenot MGI:MGI:1916477|Ensembl:ENSMUSG00000075700|Vega:OTTMUSG00000021242 +69228 Zfp746 MGI:MGI:1916478|Ensembl:ENSMUSG00000057691|Vega:OTTMUSG00000057223 +69232 Qrich1 MGI:MGI:1916482|Ensembl:ENSMUSG00000006673|Vega:OTTMUSG00000050759 +69234 Zfp688 MGI:MGI:1916484|Ensembl:ENSMUSG00000045251|Vega:OTTMUSG00000022488 +69236 2610034E01Rik MGI:MGI:1916486 +69237 Gtpbp4 MGI:MGI:1916487|Ensembl:ENSMUSG00000021149 +69239 Pdzph1 MGI:MGI:1916489|Ensembl:ENSMUSG00000024227|Vega:OTTMUSG00000033584 +69241 Polr2d MGI:MGI:1916491|Ensembl:ENSMUSG00000024258 +69248 2610035F20Rik MGI:MGI:1916498|Ensembl:ENSMUSG00000085555 +69250 2610029K11Rik MGI:MGI:1916500 +69253 Hspb2 MGI:MGI:1916503|Ensembl:ENSMUSG00000038086|Vega:OTTMUSG00000063075 +69256 Zfp397 MGI:MGI:1916506|Ensembl:ENSMUSG00000024276 +69257 Elf2 MGI:MGI:1916507|Ensembl:ENSMUSG00000037174|Vega:OTTMUSG00000051593 +69258 2610030P05Rik MGI:MGI:1916508 +69259 Kctd5 MGI:MGI:1916509|Ensembl:ENSMUSG00000016946|Vega:OTTMUSG00000023867 +69260 Ing2 MGI:MGI:1916510|Ensembl:ENSMUSG00000063049|Vega:OTTMUSG00000017299 +69261 2810411K19Rik MGI:MGI:1916511 +69263 Rfc3 MGI:MGI:1916513|Ensembl:ENSMUSG00000033970|Vega:OTTMUSG00000028751 +69269 Scnm1 MGI:MGI:1341284|Ensembl:ENSMUSG00000092607|Vega:OTTMUSG00000022306 +69270 Gins1 MGI:MGI:1916520|Ensembl:ENSMUSG00000027454|Vega:OTTMUSG00000015786 +69271 3200001G23Rik MGI:MGI:1916521 +69274 Ctdspl MGI:MGI:1916524|Ensembl:ENSMUSG00000047409|Vega:OTTMUSG00000038049 +69276 Sec62 MGI:MGI:1916526|Ensembl:ENSMUSG00000027706|Vega:OTTMUSG00000051809 +69277 3300002I08Rik MGI:MGI:1916527|Ensembl:ENSMUSG00000063364|Vega:OTTMUSG00000015736 +69279 1700001D01Rik MGI:MGI:1916529|Ensembl:ENSMUSG00000099419 +69281 Spata4 MGI:MGI:1916531|Ensembl:ENSMUSG00000031518|Vega:OTTMUSG00000060621 +69282 1700001J03Rik MGI:MGI:1916532|Ensembl:ENSMUSG00000095040|Vega:OTTMUSG00000044990 +69285 1700011L03Rik MGI:MGI:1916535 +69286 Glipr1l1 MGI:MGI:1916536|Ensembl:ENSMUSG00000020213 +69287 Odf3 MGI:MGI:1916537|Ensembl:ENSMUSG00000025482|Vega:OTTMUSG00000023467 +69288 Rhobtb1 MGI:MGI:1916538|Ensembl:ENSMUSG00000019944|Vega:OTTMUSG00000035399 +69291 1700001L05Rik MGI:MGI:1916541 +69293 1700001C07Rik MGI:MGI:1916543 +69294 Cst13 MGI:MGI:1916544|Ensembl:ENSMUSG00000036924|Vega:OTTMUSG00000015721 +69295 Far1os MGI:MGI:1916545|Ensembl:ENSMUSG00000084984 +69296 Tmigd3 MGI:MGI:5604098|Ensembl:ENSMUSG00000000562|Ensembl:ENSMUSG00000074344|Vega:OTTMUSG00000052379|Vega:OTTMUSG00000055001 +69297 Lrrc46 MGI:MGI:1916547|Ensembl:ENSMUSG00000020878|Vega:OTTMUSG00000001861 +69299 Asb9 MGI:MGI:1916549|Ensembl:ENSMUSG00000031384|Vega:OTTMUSG00000019520 +69301 Tescl MGI:MGI:1916551|Ensembl:ENSMUSG00000055826|Vega:OTTMUSG00000058074 +69303 1700001G11Rik MGI:MGI:1916553|Ensembl:ENSMUSG00000085984 +69304 1700001A13Rik MGI:MGI:1916554 +69305 Dcps MGI:MGI:1916555|Ensembl:ENSMUSG00000032040|Vega:OTTMUSG00000031937 +69306 Efcab9 MGI:MGI:1916556|Ensembl:ENSMUSG00000044056|Vega:OTTMUSG00000005380 +69307 Pxt1 MGI:MGI:1916557|Ensembl:ENSMUSG00000045378|Vega:OTTMUSG00000031641 +69308 1700007P06Rik MGI:MGI:1916558|Ensembl:ENSMUSG00000089730 +69309 Slc16a13 MGI:MGI:1916559|Ensembl:ENSMUSG00000044367|Vega:OTTMUSG00000006037 +69310 Pacrg MGI:MGI:1916560|Ensembl:ENSMUSG00000037196|Vega:OTTMUSG00000031249 +69311 1700008K24Rik MGI:MGI:1916561|Ensembl:ENSMUSG00000101012 +69312 Ppp1r42 MGI:MGI:1921138|Ensembl:ENSMUSG00000025916|Vega:OTTMUSG00000026413 +69314 Izumo3 MGI:MGI:1916564|Ensembl:ENSMUSG00000028533|Vega:OTTMUSG00000007916 +69315 1700001L19Rik MGI:MGI:1916565|Ensembl:ENSMUSG00000021534 +69317 Hmgb4 MGI:MGI:1916567|Ensembl:ENSMUSG00000048686|Vega:OTTMUSG00000009452 +69318 1700007K09Rik MGI:MGI:1916568|Ensembl:ENSMUSG00000030858|Vega:OTTMUSG00000045957 +69319 1700001K23Rik MGI:MGI:1916569 +69320 1700007J10Rik MGI:MGI:1916570|Ensembl:ENSMUSG00000086330 +69324 1700012B07Rik MGI:MGI:1916574|Ensembl:ENSMUSG00000020617|Vega:OTTMUSG00000003349 +69325 1700012B09Rik MGI:MGI:1916575|Ensembl:ENSMUSG00000031927|Vega:OTTMUSG00000045109 +69327 1700007K13Rik MGI:MGI:1916577|Ensembl:ENSMUSG00000026831|Vega:OTTMUSG00000011647 +69329 Cfap206 MGI:MGI:1916579|Ensembl:ENSMUSG00000028294|Vega:OTTMUSG00000006414 +69332 Lelp1 MGI:MGI:1916582|Ensembl:ENSMUSG00000027927|Vega:OTTMUSG00000052637 +69334 1700012I11Rik MGI:MGI:1916584|Ensembl:ENSMUSG00000102069 +69337 1700012C14Rik MGI:MGI:1916587|Ensembl:ENSMUSG00000085470 +69338 1700003D09Rik MGI:MGI:1916588|Ensembl:ENSMUSG00000085944 +69339 Ccdc54 MGI:MGI:1916589|Ensembl:ENSMUSG00000050685 +69341 1700010B09Rik MGI:MGI:1916591 +69345 1700003C15Rik MGI:MGI:1916595|Ensembl:ENSMUSG00000099391 +69347 1700008P02Rik MGI:MGI:1916597|Ensembl:ENSMUSG00000069118|Vega:OTTMUSG00000045097 +69349 1700008O03Rik MGI:MGI:1916599|Ensembl:ENSMUSG00000008028|Vega:OTTMUSG00000023974 +69350 1700003G18Rik MGI:MGI:1916600|Ensembl:ENSMUSG00000087621 +69351 Smim23 MGI:MGI:1916601|Ensembl:ENSMUSG00000020270|Vega:OTTMUSG00000005383 +69352 Necab1 MGI:MGI:1916602|Ensembl:ENSMUSG00000040536|Vega:OTTMUSG00000004586 +69354 Slc38a4 MGI:MGI:1916604|Ensembl:ENSMUSG00000022464 +69355 1700010J16Rik MGI:MGI:1916605|Ensembl:ENSMUSG00000100314 +69356 1700003I22Rik MGI:MGI:1916606|Ensembl:ENSMUSG00000100372 +69357 BC061195 MGI:MGI:4361273|Ensembl:ENSMUSG00000096153 +69358 Lrrc51 MGI:MGI:1916608|Ensembl:ENSMUSG00000064307|Vega:OTTMUSG00000023365 +69361 Cypt3 MGI:MGI:1916611|Ensembl:ENSMUSG00000048573|Vega:OTTMUSG00000019382 +69362 Cst12 MGI:MGI:1916612|Ensembl:ENSMUSG00000027443|Vega:OTTMUSG00000015722 +69363 Spaca4 MGI:MGI:1916613|Ensembl:ENSMUSG00000070563|Vega:OTTMUSG00000033718 +69364 1700012P22Rik MGI:MGI:1916614|Ensembl:ENSMUSG00000028589|Vega:OTTMUSG00000010542 +69366 1700013A02Rik MGI:MGI:1916616 +69367 Glrx2 MGI:MGI:1916617|Ensembl:ENSMUSG00000018196|Vega:OTTMUSG00000020841 +69368 Wdfy1 MGI:MGI:1916618|Ensembl:ENSMUSG00000073643|Vega:OTTMUSG00000021445 +69369 1700017D01Rik MGI:MGI:1916619|Ensembl:ENSMUSG00000024729|Vega:OTTMUSG00000047036 +69370 1700017L05Rik MGI:MGI:1916620|Ensembl:ENSMUSG00000107232 +69371 Smco2 MGI:MGI:1916621|Ensembl:ENSMUSG00000030292|Vega:OTTMUSG00000024461 +69372 Mocs3 MGI:MGI:1916622|Ensembl:ENSMUSG00000074576|Vega:OTTMUSG00000016050 +69374 1700023A20Rik MGI:MGI:1916624 +69376 Zpbp2 MGI:MGI:1916626|Ensembl:ENSMUSG00000017195|Vega:OTTMUSG00000006364 +69379 C8g MGI:MGI:88237|Ensembl:ENSMUSG00000015083|Vega:OTTMUSG00000012120 +69380 1700013G24Rik MGI:MGI:1916630|Ensembl:ENSMUSG00000041399|Vega:OTTMUSG00000009878 +69382 1700024P04Rik MGI:MGI:1916632|Ensembl:ENSMUSG00000045022|Vega:OTTMUSG00000033617 +69384 Tmem89 MGI:MGI:1916634|Ensembl:ENSMUSG00000025652|Vega:OTTMUSG00000051042 +69386 Hist1h4h MGI:MGI:2448427|Ensembl:ENSMUSG00000060981|Vega:OTTMUSG00000000568 +69387 Dnajb13 MGI:MGI:1916637|Ensembl:ENSMUSG00000030708|Vega:OTTMUSG00000025244 +69388 1700018G05Rik MGI:MGI:1916638|Ensembl:ENSMUSG00000109745|Vega:OTTMUSG00000060370 +69389 H2bfm MGI:MGI:1916639|Ensembl:ENSMUSG00000048155|Vega:OTTMUSG00000017259 +69391 1700018A14Rik MGI:MGI:1916641 +69392 1700024P12Rik MGI:MGI:1916642 +69393 1700024B18Rik MGI:MGI:1916643|Ensembl:ENSMUSG00000099994 +69395 1700018P22Rik MGI:MGI:1916645 +69396 1700018F24Rik MGI:MGI:1916646|Ensembl:ENSMUSG00000029620|Vega:OTTMUSG00000045121 +69397 1700019A02Rik MGI:MGI:1916647|Ensembl:ENSMUSG00000060715|Vega:OTTMUSG00000046891 +69398 Cdhr4 MGI:MGI:1916648|Ensembl:ENSMUSG00000032595|Vega:OTTMUSG00000042007 +69399 1700025G04Rik MGI:MGI:1916649|Ensembl:ENSMUSG00000032666|Vega:OTTMUSG00000029402 +69400 1700025A08Rik MGI:MGI:1916650 +69401 Plac8l1 MGI:MGI:1916651|Ensembl:ENSMUSG00000059455 +69402 1700019F05Rik MGI:MGI:1916652|Ensembl:ENSMUSG00000107027 +69404 Prss23os MGI:MGI:1916654 +69405 1700019E08Rik MGI:MGI:1916655|Ensembl:ENSMUSG00000086202 +69407 1700025J12Rik MGI:MGI:1916657|Ensembl:ENSMUSG00000108409 +69408 Dnajc17 MGI:MGI:1916658|Ensembl:ENSMUSG00000034278|Vega:OTTMUSG00000015761 +69409 1700021N21Rik MGI:MGI:1916659|Ensembl:ENSMUSG00000087343 +69410 1700025O18Rik MGI:MGI:1916660 +69412 1700016L04Rik MGI:MGI:1916662|Ensembl:ENSMUSG00000019865 +69413 1700016P04Rik MGI:MGI:1916663|Ensembl:ENSMUSG00000101894 +69415 1700025N21Rik MGI:MGI:1916665 +69416 1700025F22Rik MGI:MGI:1916666|Ensembl:ENSMUSG00000024728|Vega:OTTMUSG00000042673 +69418 1700025K24Rik MGI:MGI:1916668|Ensembl:ENSMUSG00000099747 +69419 1700026F02Rik MGI:MGI:1916669|Ensembl:ENSMUSG00000101854 +69420 1700022H16Rik MGI:MGI:1916670|Ensembl:ENSMUSG00000099360 +69421 1700022F17Rik MGI:MGI:1916671 +69423 1700019M22Rik MGI:MGI:1916673 +69424 1700016F12Rik MGI:MGI:1916674 +69427 1700016B15Rik MGI:MGI:1916677 +69428 1700016C15Rik MGI:MGI:1916678|Ensembl:ENSMUSG00000015962|Vega:OTTMUSG00000029757 +69430 1700048O20Rik MGI:MGI:1920637|Ensembl:ENSMUSG00000043773 +69431 1700022N22Rik MGI:MGI:1916681|Ensembl:ENSMUSG00000097523 +69432 1700026J14Rik MGI:MGI:1916682|Ensembl:ENSMUSG00000097716 +69433 1700023F02Rik MGI:MGI:1916683|Ensembl:ENSMUSG00000100000 +69434 Snhg10 MGI:MGI:1916684|Ensembl:ENSMUSG00000113722 +69437 1700020D12Rik MGI:MGI:1916687 +69438 1700020D14Rik MGI:MGI:1916688|Ensembl:ENSMUSG00000101796 +69439 Mroh4 MGI:MGI:1916689|Ensembl:ENSMUSG00000022603|Vega:OTTMUSG00000033553 +69440 Dennd6b MGI:MGI:1916690|Ensembl:ENSMUSG00000015377 +69441 1700023F06Rik MGI:MGI:1916691|Ensembl:ENSMUSG00000020940|Vega:OTTMUSG00000003034 +69442 1700023H06Rik MGI:MGI:1916692 +69443 1700027J07Rik MGI:MGI:1916693|Ensembl:ENSMUSG00000111422 +69444 Lyzl6 MGI:MGI:1916694|Ensembl:ENSMUSG00000020945|Vega:OTTMUSG00000003023 +69445 1700023D09Rik MGI:MGI:1916695 +69447 1700027A13Rik MGI:MGI:1916697 +69449 1700027A15Rik MGI:MGI:1916699|Ensembl:ENSMUSG00000101968 +69452 1700027M17Rik MGI:MGI:1916702 +69453 Prss56 MGI:MGI:1916703|Ensembl:ENSMUSG00000036480|Vega:OTTMUSG00000033560 +69454 Clic3 MGI:MGI:1916704|Ensembl:ENSMUSG00000015093|Vega:OTTMUSG00000012117 +69456 Commd10 MGI:MGI:1916706|Ensembl:ENSMUSG00000042705 +69457 Tmem45a2 MGI:MGI:1916707|Ensembl:ENSMUSG00000046748 +69459 Ubl7 MGI:MGI:1916709|Ensembl:ENSMUSG00000055720|Vega:OTTMUSG00000063209 +69460 1700028M03Rik MGI:MGI:1916710|Ensembl:ENSMUSG00000101334 +69462 Slurp2 MGI:MGI:1916712|Ensembl:ENSMUSG00000075605|Vega:OTTMUSG00000045145 +69464 Krtap4-13 MGI:MGI:1916714|Ensembl:ENSMUSG00000048294|Vega:OTTMUSG00000002186 +69469 Tmco2 MGI:MGI:1916719|Ensembl:ENSMUSG00000078577|Vega:OTTMUSG00000008912 +69470 Tmem127 MGI:MGI:1916720|Ensembl:ENSMUSG00000034850|Vega:OTTMUSG00000016014 +69473 Krtap3-1 MGI:MGI:1916723|Ensembl:ENSMUSG00000047564|Vega:OTTMUSG00000004961 +69476 1700029M03Rik MGI:MGI:1916726 +69477 2300009N04Rik MGI:MGI:1916727 +69478 2300009A05Rik MGI:MGI:1916728|Ensembl:ENSMUSG00000032403|Vega:OTTMUSG00000045985 +69479 1700029J07Rik MGI:MGI:1916729|Ensembl:ENSMUSG00000071103|Vega:OTTMUSG00000027155 +69480 Ttc9 MGI:MGI:1916730|Ensembl:ENSMUSG00000042734 +69481 Actl9 MGI:MGI:1916731|Ensembl:ENSMUSG00000092519|Vega:OTTMUSG00000037199 +69482 Nup35 MGI:MGI:1916732|Ensembl:ENSMUSG00000026999|Vega:OTTMUSG00000018807 +69487 Ndufaf5 MGI:MGI:1916737|Ensembl:ENSMUSG00000027384|Vega:OTTMUSG00000015599 +69489 2310007J06Rik MGI:MGI:1916739 +69491 1700029N11Rik MGI:MGI:1916741|Ensembl:ENSMUSG00000098144 +69495 1700029B22Rik MGI:MGI:1916745|Ensembl:ENSMUSG00000100759 +69496 Dydc1 MGI:MGI:1916746|Ensembl:ENSMUSG00000021790|Vega:OTTMUSG00000033341 +69498 2310007H11Rik MGI:MGI:1916748 +69499 Tsr2 MGI:MGI:1916749|Ensembl:ENSMUSG00000025264|Vega:OTTMUSG00000019291 +69501 Etd MGI:MGI:1916751|Ensembl:ENSMUSG00000060967|Vega:OTTMUSG00000017353 +69503 1700030I03Rik MGI:MGI:1916753 +69504 Zfp932 MGI:MGI:1916754|Ensembl:ENSMUSG00000066613|Vega:OTTMUSG00000022003 +69506 In(10)17Rk-p MGI:MGI:104055 +69511 Klk12 MGI:MGI:1916761|Ensembl:ENSMUSG00000044430|Vega:OTTMUSG00000022522 +69513 1700030C10Rik MGI:MGI:1916763|Ensembl:ENSMUSG00000099759 +69514 Lce3e MGI:MGI:1916764|Ensembl:ENSMUSG00000074433|Vega:OTTMUSG00000045075 +69515 1700030E10Rik MGI:MGI:1916765 +69517 2310001K24Rik MGI:MGI:1916767|Ensembl:ENSMUSG00000053353 +69519 Rwdd2a MGI:MGI:1916769|Ensembl:ENSMUSG00000032417|Vega:OTTMUSG00000045045 +69520 Lce3f MGI:MGI:1916770|Ensembl:ENSMUSG00000068885|Vega:OTTMUSG00000051907 +69522 2310002D06Rik MGI:MGI:1916772|Ensembl:ENSMUSG00000112701 +69524 Esam MGI:MGI:1916774|Ensembl:ENSMUSG00000001946|Vega:OTTMUSG00000033362 +69527 Mrps9 MGI:MGI:1916777|Ensembl:ENSMUSG00000060679|Vega:OTTMUSG00000046302 +69528 1700030J22Rik MGI:MGI:1916778|Ensembl:ENSMUSG00000031847|Vega:OTTMUSG00000061720 +69533 Krtap26-1 MGI:MGI:1916783|Ensembl:ENSMUSG00000071471 +69534 Avpi1 MGI:MGI:1916784|Ensembl:ENSMUSG00000018821|Vega:OTTMUSG00000034225 +69535 Ten1 MGI:MGI:1916785|Ensembl:ENSMUSG00000020778|Vega:OTTMUSG00000003843 +69536 Hemk1 MGI:MGI:1916786|Ensembl:ENSMUSG00000032579|Vega:OTTMUSG00000030257 +69537 Dnase1l1 MGI:MGI:109628|Ensembl:ENSMUSG00000019088|Vega:OTTMUSG00000017644 +69538 Antxr1 MGI:MGI:1916788|Ensembl:ENSMUSG00000033420|Vega:OTTMUSG00000057167 +69539 Trnp1 MGI:MGI:1916789|Ensembl:ENSMUSG00000056596|Vega:OTTMUSG00000011157 +69540 Klk10 MGI:MGI:1916790|Ensembl:ENSMUSG00000030693|Vega:OTTMUSG00000058309 +69541 Lyg1 MGI:MGI:1916791|Ensembl:ENSMUSG00000026085|Vega:OTTMUSG00000022170 +69542 2300002M23Rik MGI:MGI:1916792|Ensembl:ENSMUSG00000039269|Vega:OTTMUSG00000037246 +69543 Capns2 MGI:MGI:1916793|Ensembl:ENSMUSG00000078144|Vega:OTTMUSG00000024692 +69544 Wdr5b MGI:MGI:1916794|Ensembl:ENSMUSG00000034379 +69546 Mapk1ip1 MGI:MGI:1916796|Ensembl:ENSMUSG00000041775|Vega:OTTMUSG00000029361 +69547 Nkpd1 MGI:MGI:1916797|Ensembl:ENSMUSG00000060621|Vega:OTTMUSG00000059246 +69548 2310015A10Rik MGI:MGI:1916798 +69549 2310009B15Rik MGI:MGI:1916799|Ensembl:ENSMUSG00000079283|Vega:OTTMUSG00000049925 +69550 Bst2 MGI:MGI:1916800|Ensembl:ENSMUSG00000046718|Vega:OTTMUSG00000062160 +69551 2310022B05Rik MGI:MGI:1916801|Ensembl:ENSMUSG00000031983|Vega:OTTMUSG00000061563 +69553 Ripor3 MGI:MGI:1916803|Ensembl:ENSMUSG00000074577|Vega:OTTMUSG00000016051 +69554 Klhdc2 MGI:MGI:1916804|Ensembl:ENSMUSG00000020978|Vega:OTTMUSG00000023685 +69555 2310033F14Rik MGI:MGI:1916805 +69556 Bod1 MGI:MGI:1916806|Ensembl:ENSMUSG00000044502|Vega:OTTMUSG00000005361 +69561 2310015A16Rik MGI:MGI:1916811 +69562 Cdk13 MGI:MGI:1916812|Ensembl:ENSMUSG00000041297 +69563 Mrln MGI:MGI:1916813|Ensembl:ENSMUSG00000019933|Vega:OTTMUSG00000046041 +69564 Nmrk2 MGI:MGI:1916814|Ensembl:ENSMUSG00000004939 +69565 2310015K22Rik MGI:MGI:1916815 +69566 2310016D03Rik MGI:MGI:1916816|Ensembl:ENSMUSG00000102098 +69568 Vkorc1l1 MGI:MGI:1916818|Ensembl:ENSMUSG00000066735|Vega:OTTMUSG00000055677 +69571 2310034O05Rik MGI:MGI:1916821|Ensembl:ENSMUSG00000100157 +69572 Mfsd3 MGI:MGI:1916822|Ensembl:ENSMUSG00000019080 +69573 Hilpda MGI:MGI:1916823|Ensembl:ENSMUSG00000043421|Vega:OTTMUSG00000024495 +69574 Cmbl MGI:MGI:1916824|Ensembl:ENSMUSG00000022235|Vega:OTTMUSG00000022674 +69576 Smco1 MGI:MGI:1916826|Ensembl:ENSMUSG00000046345|Vega:OTTMUSG00000024749 +69577 Fastkd3 MGI:MGI:1916827|Ensembl:ENSMUSG00000021532 +69578 2310016G11Rik MGI:MGI:1916828|Ensembl:ENSMUSG00000070574 +69579 2310034P14Rik MGI:MGI:1916829 +69581 Rhou MGI:MGI:1916831|Ensembl:ENSMUSG00000039960|Vega:OTTMUSG00000027612 +69582 Plekhm2 MGI:MGI:1916832|Ensembl:ENSMUSG00000028917|Vega:OTTMUSG00000010343 +69583 Tnfsf13 MGI:MGI:1916833|Ensembl:ENSMUSG00000089669|Vega:OTTMUSG00000006001 +69584 2310035O12Rik MGI:MGI:1916834 +69585 Hfe2 MGI:MGI:1916835|Ensembl:ENSMUSG00000038403|Vega:OTTMUSG00000053135 +69587 Pcgf3 MGI:MGI:1916837|Ensembl:ENSMUSG00000033623|Vega:OTTMUSG00000017424 +69590 Gpx8 MGI:MGI:1916840|Ensembl:ENSMUSG00000021760 +69591 Mdrl MGI:MGI:1916841|Ensembl:ENSMUSG00000097468 +69592 Odam MGI:MGI:1916842|Ensembl:ENSMUSG00000009580|Vega:OTTMUSG00000033568 +69593 2310026I22Rik MGI:MGI:1916843 +69594 2310026L22Rik MGI:MGI:1916844 +69595 Frmd8os MGI:MGI:3704490 +69596 Ap5s1 MGI:MGI:1916846|Ensembl:ENSMUSG00000068264|Vega:OTTMUSG00000016038 +69597 Afg3l2 MGI:MGI:1916847|Ensembl:ENSMUSG00000024527 +69601 Dab2ip MGI:MGI:1916851|Ensembl:ENSMUSG00000026883|Vega:OTTMUSG00000012149 +69602 Otop3 MGI:MGI:1916852|Ensembl:ENSMUSG00000018862|Vega:OTTMUSG00000003747 +69603 2310020H05Rik MGI:MGI:1916853|Ensembl:ENSMUSG00000100410 +69605 Lnpk MGI:MGI:1918115|Ensembl:ENSMUSG00000009207|Vega:OTTMUSG00000013305 +69606 Mtfmt MGI:MGI:1916856|Ensembl:ENSMUSG00000059183|Vega:OTTMUSG00000022955 +69607 2310011C19Rik MGI:MGI:1916857 +69608 Sec24d MGI:MGI:1916858|Ensembl:ENSMUSG00000039234|Vega:OTTMUSG00000052539 +69610 2310011E23Rik MGI:MGI:1916860 +69611 Lce1d MGI:MGI:1916861|Ensembl:ENSMUSG00000103243|Vega:OTTMUSG00000051851 +69612 Kansl2 MGI:MGI:1916862|Ensembl:ENSMUSG00000022992 +69617 Pitrm1 MGI:MGI:1916867|Ensembl:ENSMUSG00000021193 +69621 2310031A07Rik MGI:MGI:1916871 +69623 Zfp33b MGI:MGI:1916873 +69625 2310014F06Rik MGI:MGI:1916875 +69627 Fam89a MGI:MGI:1916877|Ensembl:ENSMUSG00000043068|Vega:OTTMUSG00000061565 +69629 2310039L15Rik MGI:MGI:1916879|Ensembl:ENSMUSG00000100550 +69631 Plet1os MGI:MGI:1916881|Ensembl:ENSMUSG00000101304 +69632 Arhgef12 MGI:MGI:1916882|Ensembl:ENSMUSG00000059495|Vega:OTTMUSG00000063617 +69634 Clybl MGI:MGI:1916884|Ensembl:ENSMUSG00000025545 +69635 Dapk1 MGI:MGI:1916885|Ensembl:ENSMUSG00000021559 +69638 Enho MGI:MGI:1916888|Ensembl:ENSMUSG00000028445|Vega:OTTMUSG00000006661 +69639 Exosc8 MGI:MGI:1916889|Ensembl:ENSMUSG00000027752|Vega:OTTMUSG00000028205 +69640 Fam83g MGI:MGI:1916890|Ensembl:ENSMUSG00000042377|Vega:OTTMUSG00000005842 +69641 Wdr20 MGI:MGI:1916891|Ensembl:ENSMUSG00000037957|Vega:OTTMUSG00000050101 +69642 Mlip MGI:MGI:1916892|Ensembl:ENSMUSG00000032355|Vega:OTTMUSG00000044846 +69652 2310069B03Rik MGI:MGI:1916902|Ensembl:ENSMUSG00000100291 +69654 Dctn2 MGI:MGI:107733|Ensembl:ENSMUSG00000025410 +69655 Cd164l2 MGI:MGI:1916905|Ensembl:ENSMUSG00000028865|Vega:OTTMUSG00000010478 +69656 Pir MGI:MGI:1916906|Ensembl:ENSMUSG00000031379|Vega:OTTMUSG00000019513 +69657 2310047D07Rik MGI:MGI:1916907 +69659 2310069G16Rik MGI:MGI:1916909|Ensembl:ENSMUSG00000097102 +69660 Tmbim1 MGI:MGI:1916910|Ensembl:ENSMUSG00000006301|Vega:OTTMUSG00000021738 +69661 2310061N02Rik MGI:MGI:1916911|Ensembl:ENSMUSG00000050704|Vega:OTTMUSG00000046214 +69662 2310061I04Rik MGI:MGI:1916912|Ensembl:ENSMUSG00000050705|Vega:OTTMUSG00000033080 +69663 Ddx51 MGI:MGI:1916913|Ensembl:ENSMUSG00000029504|Vega:OTTMUSG00000026239 +69664 Krtap1-5 MGI:MGI:1916914|Ensembl:ENSMUSG00000047253|Vega:OTTMUSG00000004969 +69665 Upk3bl MGI:MGI:1916915|Ensembl:ENSMUSG00000006143|Vega:OTTMUSG00000025393 +69666 Psmg4 MGI:MGI:1916916|Ensembl:ENSMUSG00000071451|Vega:OTTMUSG00000032916 +69668 Ccdc115 MGI:MGI:1916918|Ensembl:ENSMUSG00000042111|Vega:OTTMUSG00000049472 +69670 2310061D13Rik MGI:MGI:1916920 +69671 Tmem52 MGI:MGI:1916921|Ensembl:ENSMUSG00000023153|Vega:OTTMUSG00000010711 +69672 Txndc15 MGI:MGI:1916922|Ensembl:ENSMUSG00000021497 +69674 Mif4gd MGI:MGI:1916924|Ensembl:ENSMUSG00000020743|Vega:OTTMUSG00000003475 +69675 Pxdn MGI:MGI:1916925|Ensembl:ENSMUSG00000020674|Vega:OTTMUSG00000027521 +69677 Il1f8 MGI:MGI:1916927|Ensembl:ENSMUSG00000026985|Vega:OTTMUSG00000011961 +69678 Atcayos MGI:MGI:1916928 +69679 2310043O21Rik MGI:MGI:1916929|Ensembl:ENSMUSG00000102106 +69681 Cdk3-ps MGI:MGI:1916931|Ensembl:ENSMUSG00000092300 +69683 Emc10 MGI:MGI:1916933|Ensembl:ENSMUSG00000008140|Vega:OTTMUSG00000031861 +69684 Aarsd1 MGI:MGI:1916934|Ensembl:ENSMUSG00000075528|Vega:OTTMUSG00000030988 +69686 2310066D07Rik MGI:MGI:1916936 +69690 2310057B04Rik MGI:MGI:1916940 +69692 Hddc2 MGI:MGI:1916942|Ensembl:ENSMUSG00000000295|Vega:OTTMUSG00000028054 +69693 Pof1b MGI:MGI:1916943|Ensembl:ENSMUSG00000034607|Vega:OTTMUSG00000018382 +69694 Tatdn1 MGI:MGI:1916944|Ensembl:ENSMUSG00000050891 +69696 2310057N15Rik MGI:MGI:1916946|Ensembl:ENSMUSG00000048830|Vega:OTTMUSG00000046211 +69697 Camsap3 MGI:MGI:1916947|Ensembl:ENSMUSG00000044433|Vega:OTTMUSG00000059167 +69698 Slc52a3 MGI:MGI:1916948|Ensembl:ENSMUSG00000027463|Vega:OTTMUSG00000015850 +69699 2310079G19Rik MGI:MGI:1916949|Ensembl:ENSMUSG00000045331|Vega:OTTMUSG00000046244 +69700 Col22a1 MGI:MGI:1916950|Ensembl:ENSMUSG00000079022|Vega:OTTMUSG00000033423 +69702 Ndufaf1 MGI:MGI:1916952|Ensembl:ENSMUSG00000027305|Vega:OTTMUSG00000016507 +69706 Lrr1 MGI:MGI:1916956|Ensembl:ENSMUSG00000034883 +69707 Iqcg MGI:MGI:1916957|Ensembl:ENSMUSG00000035578|Vega:OTTMUSG00000024783 +69709 Ptrhd1 MGI:MGI:1916959|Ensembl:ENSMUSG00000096199 +69710 Arap1 MGI:MGI:1916960|Ensembl:ENSMUSG00000032812|Vega:OTTMUSG00000026043 +69713 Pin4 MGI:MGI:1916963|Ensembl:ENSMUSG00000079480|Vega:OTTMUSG00000018308 +69714 Tfpt MGI:MGI:1916964|Ensembl:ENSMUSG00000006335|Vega:OTTMUSG00000023400 +69716 Trip13 MGI:MGI:1916966|Ensembl:ENSMUSG00000021569|Vega:OTTMUSG00000054943 +69717 Gm10499 MGI:MGI:3702919 +69718 Ipmk MGI:MGI:1916968|Ensembl:ENSMUSG00000060733|Vega:OTTMUSG00000031016 +69719 Cad MGI:MGI:1916969|Ensembl:ENSMUSG00000013629|Vega:OTTMUSG00000022393 +69721 Nkiras1 MGI:MGI:1916971|Ensembl:ENSMUSG00000021772|Vega:OTTMUSG00000028841 +69723 Rpain MGI:MGI:1916973|Ensembl:ENSMUSG00000018449|Vega:OTTMUSG00000006076 +69724 Rnaseh2a MGI:MGI:1916974|Ensembl:ENSMUSG00000052926|Vega:OTTMUSG00000020631 +69726 Smyd3 MGI:MGI:1916976|Ensembl:ENSMUSG00000055067|Vega:OTTMUSG00000017093 +69727 Usp46 MGI:MGI:1916977|Ensembl:ENSMUSG00000054814|Vega:OTTMUSG00000026338 +69729 2410003L11Rik MGI:MGI:1916979|Ensembl:ENSMUSG00000085860 +69731 Gemin7 MGI:MGI:1916981|Ensembl:ENSMUSG00000044709|Vega:OTTMUSG00000029520 +69732 2410018L13Rik MGI:MGI:1916982|Ensembl:ENSMUSG00000073164 +69736 Nup37 MGI:MGI:1919964|Ensembl:ENSMUSG00000035351 +69737 Ttl MGI:MGI:1916987|Ensembl:ENSMUSG00000027394|Vega:OTTMUSG00000015410 +69739 2410004I01Rik MGI:MGI:1916989|Ensembl:ENSMUSG00000085338 +69740 Dph5 MGI:MGI:1916990|Ensembl:ENSMUSG00000033554|Vega:OTTMUSG00000020272 +69742 Tm2d2 MGI:MGI:1916992|Ensembl:ENSMUSG00000031556|Vega:OTTMUSG00000060507 +69743 Casz1 MGI:MGI:1196251|Ensembl:ENSMUSG00000028977|Vega:OTTMUSG00000010931 +69745 Pold4 MGI:MGI:1916995|Ensembl:ENSMUSG00000024854 +69747 Zswim7 MGI:MGI:1916997|Ensembl:ENSMUSG00000014243|Vega:OTTMUSG00000005849 +69748 Aldh16a1 MGI:MGI:1916998|Ensembl:ENSMUSG00000007833|Vega:OTTMUSG00000023570 +69749 Epb41l4aos MGI:MGI:1916999|Ensembl:ENSMUSG00000087590 +69750 2410021H03Rik MGI:MGI:1917000|Ensembl:ENSMUSG00000100572 +69752 Zfp511 MGI:MGI:1917002|Ensembl:ENSMUSG00000025470|Vega:OTTMUSG00000060572 +69754 Fbxo7 MGI:MGI:1917004|Ensembl:ENSMUSG00000001786|Vega:OTTMUSG00000028680 +69757 Leng1 MGI:MGI:1917007|Ensembl:ENSMUSG00000078813|Vega:OTTMUSG00000027905 +69761 1600015I10Rik MGI:MGI:1917011|Ensembl:ENSMUSG00000029813|Vega:OTTMUSG00000037958 +69765 1500004F05Rik MGI:MGI:1917015 +69767 1600017G08Rik MGI:MGI:1917017 +69768 1600019K03Rik MGI:MGI:1917018|Ensembl:ENSMUSG00000099429 +69769 Tnfaip8l2 MGI:MGI:1917019|Ensembl:ENSMUSG00000013707|Vega:OTTMUSG00000022314 +69770 1600002K03Rik MGI:MGI:1917020|Ensembl:ENSMUSG00000035595|Vega:OTTMUSG00000019106 +69771 1810019D21Rik MGI:MGI:1917021 +69772 Bdh2 MGI:MGI:1917022|Ensembl:ENSMUSG00000028167|Vega:OTTMUSG00000029709 +69773 Timm29 MGI:MGI:1917023|Ensembl:ENSMUSG00000048429|Vega:OTTMUSG00000045908 +69774 Ms4a6b MGI:MGI:1917024|Ensembl:ENSMUSG00000024677|Vega:OTTMUSG00000034785 +69776 1600002D24Rik MGI:MGI:1917026|Ensembl:ENSMUSG00000086899 +69780 Smap2 MGI:MGI:1917030|Ensembl:ENSMUSG00000032870|Vega:OTTMUSG00000008854 +69781 1600010M07Rik MGI:MGI:1917031|Ensembl:ENSMUSG00000101585 +69783 1600010F14Rik MGI:MGI:1917033 +69784 1500009L16Rik MGI:MGI:1917034|Ensembl:ENSMUSG00000087651 +69785 Ceacam13 MGI:MGI:1917035|Ensembl:ENSMUSG00000057195|Vega:OTTMUSG00000016943 +69786 Tprkb MGI:MGI:1917036|Ensembl:ENSMUSG00000054226|Vega:OTTMUSG00000023849 +69787 Anxa13 MGI:MGI:1917037 +69788 1600023N17Rik MGI:MGI:1917038|Ensembl:ENSMUSG00000104986 +69790 Med30 MGI:MGI:1917040|Ensembl:ENSMUSG00000038622 +69792 Med6 MGI:MGI:1917042|Ensembl:ENSMUSG00000002679|Vega:OTTMUSG00000034947 +69794 1600027J07Rik MGI:MGI:1917044|Ensembl:ENSMUSG00000110340 +69797 1600029I14Rik MGI:MGI:1917047|Ensembl:ENSMUSG00000046242 +69798 1810044D09Rik MGI:MGI:1917048|Ensembl:ENSMUSG00000100680 +69802 Cox11 MGI:MGI:1917052|Ensembl:ENSMUSG00000020544|Vega:OTTMUSG00000001603 +69804 Tmem147 MGI:MGI:1915011|Ensembl:ENSMUSG00000006315|Vega:OTTMUSG00000059370 +69806 Slc39a11 MGI:MGI:1917056|Ensembl:ENSMUSG00000041654|Vega:OTTMUSG00000003310 +69807 Trim32 MGI:MGI:1917057|Ensembl:ENSMUSG00000051675|Vega:OTTMUSG00000000317 +69808 Rap1gapos MGI:MGI:1917058 +69809 1810046K07Rik MGI:MGI:1917059|Ensembl:ENSMUSG00000036027|Vega:OTTMUSG00000042657 +69810 Clec4b1 MGI:MGI:1917060|Ensembl:ENSMUSG00000030147|Vega:OTTMUSG00000034578 +69812 Abhd11os MGI:MGI:1917062|Ensembl:ENSMUSG00000085042 +69813 2010001M07Rik MGI:MGI:1917063 +69814 Prss32 MGI:MGI:1917064|Ensembl:ENSMUSG00000048992|Vega:OTTMUSG00000028090 +69815 Krtcap3 MGI:MGI:1917065|Ensembl:ENSMUSG00000029149|Vega:OTTMUSG00000022518 +69816 Mzb1 MGI:MGI:1917066|Ensembl:ENSMUSG00000024353 +69818 1810059C17Rik MGI:MGI:1917068 +69820 1810059H22Rik MGI:MGI:1917070 +69821 Mterf4 MGI:MGI:1918355|Ensembl:ENSMUSG00000026273|Vega:OTTMUSG00000021521 +69822 Gm13594 MGI:MGI:3702953 +69823 Fyttd1 MGI:MGI:1917955|Ensembl:ENSMUSG00000022800|Vega:OTTMUSG00000026865 +69824 Glod5 MGI:MGI:1917074|Ensembl:ENSMUSG00000031163|Vega:OTTMUSG00000018009 +69826 Ms4a10 MGI:MGI:1917076|Ensembl:ENSMUSG00000024731|Vega:OTTMUSG00000046880 +69829 2010001K21Rik MGI:MGI:1917079 +69833 Polr2f MGI:MGI:1349393|Ensembl:ENSMUSG00000033020 +69834 Rab43 MGI:MGI:1917084|Ensembl:ENSMUSG00000030055|Vega:OTTMUSG00000022164 +69836 Pla2g12b MGI:MGI:1917086|Ensembl:ENSMUSG00000009646|Vega:OTTMUSG00000027944 +69837 Pcgf1 MGI:MGI:1917087|Ensembl:ENSMUSG00000069678|Vega:OTTMUSG00000039809 +69841 2010002M09Rik MGI:MGI:1917091 +69847 Wnk4 MGI:MGI:1917097|Ensembl:ENSMUSG00000035112|Vega:OTTMUSG00000002761 +69849 2010007H06Rik MGI:MGI:1917099 +69851 2010007E15Rik MGI:MGI:1917101 +69852 Tcf23 MGI:MGI:1934960|Ensembl:ENSMUSG00000006642|Vega:OTTMUSG00000055054 +69854 1810063I02Rik MGI:MGI:1917104|Ensembl:ENSMUSG00000085551 +69857 1810053B23Rik MGI:MGI:1917107|Ensembl:ENSMUSG00000100277 +69859 2010008C14Rik MGI:MGI:1917109 +69860 Eif1ad MGI:MGI:1917110|Ensembl:ENSMUSG00000024841 +69861 2010003K11Rik MGI:MGI:1917111|Ensembl:ENSMUSG00000042041 +69862 1810064F22Rik MGI:MGI:1917112|Ensembl:ENSMUSG00000090925 +69863 Ttc39b MGI:MGI:1917113|Ensembl:ENSMUSG00000038172|Vega:OTTMUSG00000000031 +69864 1810065E05Rik MGI:MGI:1917114|Ensembl:ENSMUSG00000013653|Vega:OTTMUSG00000005736 +69865 A1cf MGI:MGI:1917115|Ensembl:ENSMUSG00000052595 +69870 Polr3gl MGI:MGI:1917120|Ensembl:ENSMUSG00000028104|Vega:OTTMUSG00000032756 +69871 Ppp1r35 MGI:MGI:1922853|Ensembl:ENSMUSG00000029725|Vega:OTTMUSG00000022849 +69875 Ndufa11 MGI:MGI:1917125|Ensembl:ENSMUSG00000002379 +69876 Thap3 MGI:MGI:1917126|Ensembl:ENSMUSG00000039759|Vega:OTTMUSG00000010359 +69878 Snrpf MGI:MGI:1917128|Ensembl:ENSMUSG00000020018|Vega:OTTMUSG00000030971 +69881 2010320O07Rik MGI:MGI:1917131 +69882 Ints14 MGI:MGI:1917132|Ensembl:ENSMUSG00000034263|Vega:OTTMUSG00000062615 +69884 2010300F17Rik MGI:MGI:1917134 +69885 Aunip MGI:MGI:1917135|Ensembl:ENSMUSG00000078521|Vega:OTTMUSG00000011173 +69886 2610002J23Rik MGI:MGI:1917136 +69887 2010100M03Rik MGI:MGI:1917137 +69888 Cyp2c66 MGI:MGI:1917138|Ensembl:ENSMUSG00000067229|Vega:OTTMUSG00000028352 +69889 2010103J01Rik MGI:MGI:1917139 +69890 Zfp219 MGI:MGI:1917140|Ensembl:ENSMUSG00000049295 +69893 Coa7 MGI:MGI:1917143|Ensembl:ENSMUSG00000048351|Vega:OTTMUSG00000008241 +69894 2010107G23Rik MGI:MGI:1917144|Ensembl:ENSMUSG00000020083|Vega:OTTMUSG00000032742 +69895 Snhg8 MGI:MGI:1917145|Ensembl:ENSMUSG00000104960 +69898 2010110G14Rik MGI:MGI:1917148 +69900 Mfsd11 MGI:MGI:1917150|Ensembl:ENSMUSG00000020818|Vega:OTTMUSG00000003791 +69902 Mrto4 MGI:MGI:1917152|Ensembl:ENSMUSG00000028741|Vega:OTTMUSG00000009954 +69903 Rasip1 MGI:MGI:1917153|Ensembl:ENSMUSG00000044562|Vega:OTTMUSG00000029506 +69904 2610027F03Rik MGI:MGI:1917154 +69906 Slc25a32 MGI:MGI:1917156|Ensembl:ENSMUSG00000022299 +69908 Rab3b MGI:MGI:1917158|Ensembl:ENSMUSG00000003411|Vega:OTTMUSG00000008236 +69909 2610027K06Rik MGI:MGI:1917159|Ensembl:ENSMUSG00000087013 +69912 Nup43 MGI:MGI:1917162|Ensembl:ENSMUSG00000040034|Vega:OTTMUSG00000034979 +69915 2610509F24Rik MGI:MGI:1917165 +69916 2610020F03Rik MGI:MGI:1917166 +69917 Nabp2 MGI:MGI:1917167|Ensembl:ENSMUSG00000025374|Vega:OTTMUSG00000035847 +69918 2610020C07Rik MGI:MGI:1917168 +69920 Polr2i MGI:MGI:1917170|Ensembl:ENSMUSG00000019738|Vega:OTTMUSG00000023328 +69922 Vrk2 MGI:MGI:1917172|Ensembl:ENSMUSG00000064090|Vega:OTTMUSG00000008090 +69923 Agk MGI:MGI:1917173|Ensembl:ENSMUSG00000029916|Vega:OTTMUSG00000056333 +69926 Dnah17 MGI:MGI:1917176|Ensembl:ENSMUSG00000033987|Vega:OTTMUSG00000003882 +69928 Apitd1 MGI:MGI:1917178|Ensembl:ENSMUSG00000073705|Vega:OTTMUSG00000010953 +69930 Zfp715 MGI:MGI:1917180|Ensembl:ENSMUSG00000012640|Vega:OTTMUSG00000022471 +69932 2810004I08Rik MGI:MGI:1917182 +69934 Trmt10b MGI:MGI:1917184|Ensembl:ENSMUSG00000035601|Vega:OTTMUSG00000007526 +69938 Scrn1 MGI:MGI:1917188|Ensembl:ENSMUSG00000019124|Vega:OTTMUSG00000024705 +69940 Exoc1 MGI:MGI:2445020|Ensembl:ENSMUSG00000036435|Vega:OTTMUSG00000026487 +69941 2810408I11Rik MGI:MGI:1917191|Ensembl:ENSMUSG00000087213 +69942 Rnf113a1 MGI:MGI:1917192|Ensembl:ENSMUSG00000036537|Vega:OTTMUSG00000017123 +69944 2810021J22Rik MGI:MGI:1917194|Ensembl:ENSMUSG00000020491|Vega:OTTMUSG00000005769 +69952 Tunar MGI:MGI:1917202|Ensembl:ENSMUSG00000097929|Vega:OTTMUSG00000047117 +69953 2810025M15Rik MGI:MGI:1917203|Ensembl:ENSMUSG00000049881 +69955 Fars2 MGI:MGI:1917205|Ensembl:ENSMUSG00000021420 +69956 Ptcd3 MGI:MGI:1917206|Ensembl:ENSMUSG00000063884|Vega:OTTMUSG00000057915 +69957 Cdc16 MGI:MGI:1917207|Ensembl:ENSMUSG00000038416|Vega:OTTMUSG00000031373 +69960 2810403G07Rik MGI:MGI:1917210 +69961 Rpp25l MGI:MGI:1917211|Ensembl:ENSMUSG00000036114|Vega:OTTMUSG00000006682 +69962 Mettl18 MGI:MGI:1917212|Ensembl:ENSMUSG00000041396|Vega:OTTMUSG00000021827 +69963 2810432F15Rik MGI:MGI:1917213 +69964 2810403D21Rik MGI:MGI:1917214|Ensembl:ENSMUSG00000086629 +69966 2810404M03Rik MGI:MGI:1917216|Ensembl:ENSMUSG00000102046 +69968 2810404F17Rik MGI:MGI:1917218 +69972 2810425M01Rik MGI:MGI:1917222 +69974 2810405F15Rik MGI:MGI:1917224 +69975 2810405F17Rik MGI:MGI:1917225 +69976 Galk2 MGI:MGI:1917226|Ensembl:ENSMUSG00000027207|Vega:OTTMUSG00000015339 +69977 2810405K22Rik MGI:MGI:1917227 +69979 2810427C15Rik MGI:MGI:1917229 +69981 Tmem30a MGI:MGI:106402|Ensembl:ENSMUSG00000032328|Vega:OTTMUSG00000027405 +69982 Spink2 MGI:MGI:1917232|Ensembl:ENSMUSG00000053030|Vega:OTTMUSG00000026576 +69983 Sis MGI:MGI:1917233|Ensembl:ENSMUSG00000027790|Vega:OTTMUSG00000035151 +69984 1700025O08Rik MGI:MGI:1917234 +69986 1700025N23Rik MGI:MGI:1917236|Ensembl:ENSMUSG00000100121 +69987 Spaca9 MGI:MGI:1917237|Ensembl:ENSMUSG00000026809|Vega:OTTMUSG00000011765 +69988 2010205J10Rik MGI:MGI:1917238 +69993 Chn2 MGI:MGI:1917243|Ensembl:ENSMUSG00000004633|Vega:OTTMUSG00000023143 +69994 Rsc1a1 MGI:MGI:3526447|Ensembl:ENSMUSG00000040715|Ensembl:ENSMUSG00000078515|Vega:OTTMUSG00000010365 +69996 1700027A07Rik MGI:MGI:1917246 +69999 1700027F09Rik MGI:MGI:1917249|Ensembl:ENSMUSG00000100911 +70000 2410024N13Rik MGI:MGI:1917250 +70001 1700028B04Rik MGI:MGI:1917251|Ensembl:ENSMUSG00000099417 +70002 1700028E11Rik MGI:MGI:1917252 +70003 1700028I16Rik MGI:MGI:1917253|Ensembl:ENSMUSG00000056821 +70004 1700028J19Rik MGI:MGI:1917254|Ensembl:ENSMUSG00000038782|Vega:OTTMUSG00000058323 +70005 Znf41-ps MGI:MGI:1917255 +70007 1700029J08Rik MGI:MGI:1917257 +70008 Ace2 MGI:MGI:1917258|Ensembl:ENSMUSG00000015405|Vega:OTTMUSG00000019518 +70009 Ssty2 MGI:MGI:1917259|Ensembl:ENSMUSG00000095302|Vega:OTTMUSG00000045864 +70011 1700030N03Rik MGI:MGI:1917261|Ensembl:ENSMUSG00000100969 +70012 Cep85 MGI:MGI:1917262|Ensembl:ENSMUSG00000037443|Vega:OTTMUSG00000010361 +70016 1700030N18Rik MGI:MGI:1917266 +70018 2010309G21Rik MGI:MGI:1917268 +70019 2410039M03Rik MGI:MGI:1917269 +70020 Ino80b MGI:MGI:1917270|Ensembl:ENSMUSG00000030034|Vega:OTTMUSG00000024271 +70021 Nt5dc2 MGI:MGI:1917271|Ensembl:ENSMUSG00000071547 +70024 Mcm10 MGI:MGI:1917274|Ensembl:ENSMUSG00000026669|Vega:OTTMUSG00000010867 +70025 Acot7 MGI:MGI:1917275|Ensembl:ENSMUSG00000028937|Vega:OTTMUSG00000010306 +70026 Tspo2 MGI:MGI:1917276|Ensembl:ENSMUSG00000023995|Vega:OTTMUSG00000034774 +70028 Dopey2 MGI:MGI:1917278|Ensembl:ENSMUSG00000022946 +70031 Cmtm8 MGI:MGI:2447167|Ensembl:ENSMUSG00000041012|Vega:OTTMUSG00000062860 +70036 Dancr MGI:MGI:1917286|Ensembl:ENSMUSG00000053656 +70040 2610037D02Rik MGI:MGI:1917290 +70041 2610524E12Rik MGI:MGI:1917291 +70044 Tut1 MGI:MGI:1917294|Ensembl:ENSMUSG00000071645 +70045 2610528A11Rik MGI:MGI:1917295|Ensembl:ENSMUSG00000096001|Vega:OTTMUSG00000046703 +70047 Trnt1 MGI:MGI:1917297|Ensembl:ENSMUSG00000013736|Vega:OTTMUSG00000023531 +70050 2600014K08Rik MGI:MGI:1917300 +70052 Prpf4 MGI:MGI:1917302|Ensembl:ENSMUSG00000066148|Vega:OTTMUSG00000000234 +70054 Ccdc89 MGI:MGI:1917304|Ensembl:ENSMUSG00000044362|Vega:OTTMUSG00000059805 +70055 1700030L20Rik MGI:MGI:1917305|Ensembl:ENSMUSG00000099508 +70057 2210008F06Rik MGI:MGI:1917307 +70059 Degs2 MGI:MGI:1917309|Ensembl:ENSMUSG00000021263 +70060 Spata3 MGI:MGI:1917310|Ensembl:ENSMUSG00000026226|Vega:OTTMUSG00000026756 +70061 Sdr9c7 MGI:MGI:1917311|Ensembl:ENSMUSG00000040127|Vega:OTTMUSG00000027610 +70062 Ctag2 MGI:MGI:1917312|Ensembl:ENSMUSG00000031181|Vega:OTTMUSG00000017620 +70065 Ankrd60 MGI:MGI:1917315|Ensembl:ENSMUSG00000027517|Vega:OTTMUSG00000014943 +70069 H1fnt MGI:MGI:1917319|Ensembl:ENSMUSG00000048077 +70073 Zdhhc25 MGI:MGI:1917323|Ensembl:ENSMUSG00000054117|Vega:OTTMUSG00000042890 +70074 1700030P01Rik MGI:MGI:1917324 +70078 Nol7 MGI:MGI:1917328|Ensembl:ENSMUSG00000063200 +70080 Igsf23 MGI:MGI:1917330|Ensembl:ENSMUSG00000040498|Vega:OTTMUSG00000059294 +70081 Zfp995 MGI:MGI:1917331|Ensembl:ENSMUSG00000078546|Vega:OTTMUSG00000045959 +70082 Lysmd2 MGI:MGI:1917332|Ensembl:ENSMUSG00000032184|Vega:OTTMUSG00000062850 +70083 Metrn MGI:MGI:1917333|Ensembl:ENSMUSG00000002274 +70084 2300004M11Rik MGI:MGI:1917334 +70086 Cysltr2 MGI:MGI:1917336|Ensembl:ENSMUSG00000033470 +70088 Meaf6 MGI:MGI:1917338|Ensembl:ENSMUSG00000028863|Vega:OTTMUSG00000009252 +70090 2310005E17Rik MGI:MGI:1917340|Ensembl:ENSMUSG00000099446 +70093 Ube2q1 MGI:MGI:1917343|Ensembl:ENSMUSG00000042572|Vega:OTTMUSG00000052881 +70094 2310008B10Rik MGI:MGI:1917344 +70097 Sash1 MGI:MGI:1917347|Ensembl:ENSMUSG00000015305|Vega:OTTMUSG00000062029 +70099 Smc4 MGI:MGI:1917349|Ensembl:ENSMUSG00000034349|Vega:OTTMUSG00000024475 +70100 2310015D24Rik MGI:MGI:1917350|Ensembl:ENSMUSG00000099411 +70101 Cyp4f16 MGI:MGI:1917351|Ensembl:ENSMUSG00000048440|Vega:OTTMUSG00000036870 +70103 Znhit1 MGI:MGI:1917353|Ensembl:ENSMUSG00000059518|Vega:OTTMUSG00000023366 +70108 2610001A08Rik MGI:MGI:1917358 +70110 Ifi35 MGI:MGI:1917360|Ensembl:ENSMUSG00000010358|Vega:OTTMUSG00000002869 +70113 Odf3b MGI:MGI:1917363|Ensembl:ENSMUSG00000047394 +70118 Srrd MGI:MGI:1917368|Ensembl:ENSMUSG00000029346|Vega:OTTMUSG00000023499 +70120 Yars2 MGI:MGI:1917370|Ensembl:ENSMUSG00000022792|Vega:OTTMUSG00000026531 +70122 Mllt3 MGI:MGI:1917372|Ensembl:ENSMUSG00000028496|Vega:OTTMUSG00000007699 +70123 Nbdy MGI:MGI:1917373|Ensembl:ENSMUSG00000086316|Vega:OTTMUSG00000019378 +70125 2210016H18Rik MGI:MGI:1917375 +70127 Dpf3 MGI:MGI:1917377|Ensembl:ENSMUSG00000021221|Vega:OTTMUSG00000033729 +70129 Slc44a4 MGI:MGI:1917379|Ensembl:ENSMUSG00000007034|Vega:OTTMUSG00000037275 +70133 2210406H18Rik MGI:MGI:1917383 +70134 2210011C24Rik MGI:MGI:1917384|Ensembl:ENSMUSG00000074217|Vega:OTTMUSG00000045949 +70135 2310043P16Rik MGI:MGI:1917385 +70138 2210417A02Rik MGI:MGI:1917388|Ensembl:ENSMUSG00000086494 +70141 2210414I22Rik MGI:MGI:1917391 +70143 2210414B05Rik MGI:MGI:1917393|Ensembl:ENSMUSG00000085394 +70144 Lrch3 MGI:MGI:1917394|Ensembl:ENSMUSG00000022801|Vega:OTTMUSG00000024806 +70145 2210022D18Rik MGI:MGI:1917395 +70147 Plut MGI:MGI:1917397|Ensembl:ENSMUSG00000092570 +70152 Mettl7a1 MGI:MGI:1916523|Ensembl:ENSMUSG00000054619 +70153 2210016F16Rik MGI:MGI:1917403|Ensembl:ENSMUSG00000021550|Vega:OTTMUSG00000035893 +70155 Ogfrl1 MGI:MGI:1917405|Ensembl:ENSMUSG00000026158|Vega:OTTMUSG00000046267 +70156 2310046G18Rik MGI:MGI:1917406 +70157 2210409D07Rik MGI:MGI:1917407 +70160 Vps36 MGI:MGI:1917410|Ensembl:ENSMUSG00000031479|Vega:OTTMUSG00000027110 +70162 Hk1os MGI:MGI:1917412 +70163 Lypd8 MGI:MGI:1917413|Ensembl:ENSMUSG00000013643|Vega:OTTMUSG00000005733 +70165 2310044K18Rik MGI:MGI:1917415 +70166 Lipn MGI:MGI:1917416|Ensembl:ENSMUSG00000024770|Vega:OTTMUSG00000029762 +70167 2210414F02Rik MGI:MGI:1917417 +70176 2210411M09Rik MGI:MGI:1917426 +70177 2210415C06Rik MGI:MGI:1917427 +70178 Abhd17c MGI:MGI:1917428|Ensembl:ENSMUSG00000038459|Vega:OTTMUSG00000028921 +70184 2310066N15Rik MGI:MGI:1917434 +70185 2310068G24Rik MGI:MGI:1917435 +70186 Fam162a MGI:MGI:1917436|Ensembl:ENSMUSG00000003955 +70190 2610036A22Rik MGI:MGI:1917440 +70192 Cd209g MGI:MGI:1917442|Ensembl:ENSMUSG00000079168|Vega:OTTMUSG00000033965 +70194 2310075C17Rik MGI:MGI:1917444 +70202 Ctsll3 MGI:MGI:1917452|Ensembl:ENSMUSG00000056728 +70203 2310061B05Rik MGI:MGI:1917453 +70205 2310068C19Rik MGI:MGI:1917455 +70207 Taco1 MGI:MGI:1917457|Ensembl:ENSMUSG00000001983|Vega:OTTMUSG00000003077 +70208 Med23 MGI:MGI:1917458|Ensembl:ENSMUSG00000019984|Vega:OTTMUSG00000039802 +70209 Tmem143 MGI:MGI:1917459|Ensembl:ENSMUSG00000002781|Vega:OTTMUSG00000022315 +70213 2310075M01Rik MGI:MGI:1917463 +70218 Kif18b MGI:MGI:2446979|Ensembl:ENSMUSG00000051378|Vega:OTTMUSG00000003098 +70223 Nars MGI:MGI:1917473|Ensembl:ENSMUSG00000024587 +70225 Ppil3 MGI:MGI:1917475|Ensembl:ENSMUSG00000026035|Vega:OTTMUSG00000021988 +70226 Rbm3os MGI:MGI:1917476|Ensembl:ENSMUSG00000055188 +70227 Zfp619 MGI:MGI:1917477|Ensembl:ENSMUSG00000068959|Vega:OTTMUSG00000022424 +70230 3300002P13Rik MGI:MGI:1917480|Ensembl:ENSMUSG00000107585 +70231 Gorasp2 MGI:MGI:2135962|Ensembl:ENSMUSG00000014959|Vega:OTTMUSG00000013118 +70233 Cd2bp2 MGI:MGI:1917483|Ensembl:ENSMUSG00000042502|Vega:OTTMUSG00000058498 +70235 Poc1a MGI:MGI:1917485|Ensembl:ENSMUSG00000023345|Vega:OTTMUSG00000049423 +70237 Bhlhb9 MGI:MGI:1917487|Ensembl:ENSMUSG00000072964|Vega:OTTMUSG00000018769 +70238 Rnf168 MGI:MGI:1917488|Ensembl:ENSMUSG00000014074|Vega:OTTMUSG00000025774 +70239 Gtf3c5 MGI:MGI:1917489|Ensembl:ENSMUSG00000026816|Vega:OTTMUSG00000011674 +70240 Ufsp1 MGI:MGI:1917490|Ensembl:ENSMUSG00000051502|Vega:OTTMUSG00000028193 +70241 2810416A17Rik MGI:MGI:1917491 +70246 3300002P09Rik MGI:MGI:1917496 +70247 Psmd1 MGI:MGI:1917497|Ensembl:ENSMUSG00000026229|Vega:OTTMUSG00000033949 +70248 Dazap1 MGI:MGI:1917498|Ensembl:ENSMUSG00000069565|Vega:OTTMUSG00000000016 +70249 3100002H09Rik MGI:MGI:1917499 +70251 2010105D22Rik MGI:MGI:1917501 +70252 Jpx MGI:MGI:2180008|Ensembl:ENSMUSG00000097571 +70256 2010107C10Rik MGI:MGI:1917506 +70257 2010107E04Rik MGI:MGI:1917507|Ensembl:ENSMUSG00000021290 +70258 1500035N22Rik MGI:MGI:1917508 +70261 Chp2 MGI:MGI:1917511|Ensembl:ENSMUSG00000030865|Vega:OTTMUSG00000034703 +70265 2010109P13Rik MGI:MGI:1917515 +70266 Kyat1 MGI:MGI:1917516|Ensembl:ENSMUSG00000039648|Vega:OTTMUSG00000016753 +70267 2010109K09Rik MGI:MGI:1917517 +70274 Ly6g6e MGI:MGI:1917524|Ensembl:ENSMUSG00000013766|Vega:OTTMUSG00000037162 +70275 2310061L18Rik MGI:MGI:1917525 +70277 2310026G15Rik MGI:MGI:1917527 +70281 2310068J16Rik MGI:MGI:1917531|Ensembl:ENSMUSG00000100084 +70284 2310040G07Rik MGI:MGI:1917534 +70285 Rpf1 MGI:MGI:1917535|Ensembl:ENSMUSG00000028187|Vega:OTTMUSG00000055332 +70286 2310067P03Rik MGI:MGI:1917536 +70289 2510016D11Rik MGI:MGI:1917539 +70290 2310079F09Rik MGI:MGI:1917540 +70291 Mkrn2os MGI:MGI:1917541|Ensembl:ENSMUSG00000068011|Vega:OTTMUSG00000024488 +70292 Afap1 MGI:MGI:1917542|Ensembl:ENSMUSG00000029094|Vega:OTTMUSG00000024856 +70294 Rnf126 MGI:MGI:1917544|Ensembl:ENSMUSG00000035890 +70295 2610011I18Rik MGI:MGI:1917545 +70296 Tbc1d13 MGI:MGI:2385326|Ensembl:ENSMUSG00000039678|Vega:OTTMUSG00000016741 +70297 Gcc2 MGI:MGI:1917547|Ensembl:ENSMUSG00000038039|Vega:OTTMUSG00000034161 +70298 2600010L24Rik MGI:MGI:1917548 +70299 2610012C04Rik MGI:MGI:1917549 +70300 Fuz MGI:MGI:1917550|Ensembl:ENSMUSG00000011658|Vega:OTTMUSG00000035380 +70307 2510042H03Rik MGI:MGI:1917557 +70308 2610005M20Rik MGI:MGI:1917558 +70309 2610005G05Rik MGI:MGI:1917559 +70310 Plscr3 MGI:MGI:1917560|Ensembl:ENSMUSG00000019461|Vega:OTTMUSG00000006010 +70311 2510042O18Rik MGI:MGI:1917561 +70312 Cactin MGI:MGI:1917562|Ensembl:ENSMUSG00000034889 +70314 Rabep2 MGI:MGI:1917564|Ensembl:ENSMUSG00000030727|Vega:OTTMUSG00000025328 +70315 Hdac8 MGI:MGI:1917565|Ensembl:ENSMUSG00000067567|Vega:OTTMUSG00000017208 +70316 Ndufab1 MGI:MGI:1917566|Ensembl:ENSMUSG00000030869|Vega:OTTMUSG00000026510 +70317 Arl16 MGI:MGI:1917567|Ensembl:ENSMUSG00000057594|Vega:OTTMUSG00000004241 +70319 2600006K01Rik MGI:MGI:1917569 +70320 2610008G14Rik MGI:MGI:1917570 +70325 Pigw MGI:MGI:1917575|Ensembl:ENSMUSG00000045140|Vega:OTTMUSG00000001022 +70333 Cd3eap MGI:MGI:1917583|Ensembl:ENSMUSG00000047649|Vega:OTTMUSG00000042027 +70335 Reep6 MGI:MGI:1917585|Ensembl:ENSMUSG00000035504|Vega:OTTMUSG00000000018 +70337 Iyd MGI:MGI:1917587|Ensembl:ENSMUSG00000019762|Vega:OTTMUSG00000027509 +70345 0610038B21Rik MGI:MGI:1917595|Ensembl:ENSMUSG00000097882 +70348 Ube2cbp MGI:MGI:1917598|Ensembl:ENSMUSG00000032415|Vega:OTTMUSG00000031697 +70349 Copb1 MGI:MGI:1917599|Ensembl:ENSMUSG00000030754|Vega:OTTMUSG00000060372 +70350 Basp1 MGI:MGI:1917600|Ensembl:ENSMUSG00000045763 +70351 Ppp4r1 MGI:MGI:1917601|Ensembl:ENSMUSG00000061950|Vega:OTTMUSG00000034201 +70354 Secisbp2l MGI:MGI:1917604|Ensembl:ENSMUSG00000035093|Vega:OTTMUSG00000015342 +70355 Gprc5c MGI:MGI:1917605|Ensembl:ENSMUSG00000051043|Vega:OTTMUSG00000003463 +70356 St13 MGI:MGI:1917606|Ensembl:ENSMUSG00000022403|Vega:OTTMUSG00000035635 +70357 Kcnip1 MGI:MGI:1917607|Ensembl:ENSMUSG00000053519|Vega:OTTMUSG00000005402 +70358 Steap1 MGI:MGI:1917608|Ensembl:ENSMUSG00000015652|Vega:OTTMUSG00000025944 +70359 Gtpbp3 MGI:MGI:1917609|Ensembl:ENSMUSG00000007610|Vega:OTTMUSG00000029852 +70361 Lman1 MGI:MGI:1917611|Ensembl:ENSMUSG00000041891|Vega:OTTMUSG00000030654 +70362 Actl10 MGI:MGI:1917612|Ensembl:ENSMUSG00000078129|Vega:OTTMUSG00000015794 +70363 Fam135b MGI:MGI:1917613|Ensembl:ENSMUSG00000036800 +70365 Speer5-ps1 MGI:MGI:1917615|Ensembl:ENSMUSG00000091358 +70369 Bag5 MGI:MGI:1917619|Ensembl:ENSMUSG00000049792|Vega:OTTMUSG00000028789 +70370 Fbln7 MGI:MGI:1917620|Ensembl:ENSMUSG00000027386|Vega:OTTMUSG00000015350 +70371 1700026D11Rik MGI:MGI:1917621|Ensembl:ENSMUSG00000086379 +70373 Gpatch2l MGI:MGI:1917623|Ensembl:ENSMUSG00000021254 +70375 Ica1l MGI:MGI:1917625|Ensembl:ENSMUSG00000026018|Vega:OTTMUSG00000047263 +70376 1700026H06Rik MGI:MGI:1917626 +70377 Derl3 MGI:MGI:1917627|Ensembl:ENSMUSG00000009092 +70378 1810073G21Rik MGI:MGI:1917628 +70380 Mospd1 MGI:MGI:1917630|Ensembl:ENSMUSG00000023074|Vega:OTTMUSG00000017344 +70381 Tecpr1 MGI:MGI:1917631|Ensembl:ENSMUSG00000066621|Vega:OTTMUSG00000025570 +70382 Kctd2 MGI:MGI:1917632|Ensembl:ENSMUSG00000016940|Vega:OTTMUSG00000003447 +70383 Cox10 MGI:MGI:1917633|Ensembl:ENSMUSG00000042148|Vega:OTTMUSG00000005891 +70385 Spdl1 MGI:MGI:1917635|Ensembl:ENSMUSG00000069910|Vega:OTTMUSG00000008080 +70386 2210017G18Rik MGI:MGI:1917636 +70387 Ttc9c MGI:MGI:1917637|Ensembl:ENSMUSG00000071660|Vega:OTTMUSG00000032991 +70392 Asb12 MGI:MGI:1917642|Ensembl:ENSMUSG00000031204|Vega:OTTMUSG00000018082 +70393 2210416O15Rik MGI:MGI:1917643|Ensembl:ENSMUSG00000018378 +70394 Kptn MGI:MGI:1890380|Ensembl:ENSMUSG00000006021|Vega:OTTMUSG00000017419 +70396 Asnsd1 MGI:MGI:1917646|Ensembl:ENSMUSG00000026095|Vega:OTTMUSG00000046895 +70397 Tmem70 MGI:MGI:1915068|Ensembl:ENSMUSG00000025940|Vega:OTTMUSG00000042171 +70403 2310061A09Rik MGI:MGI:1917653 +70405 Calml3 MGI:MGI:1917655|Ensembl:ENSMUSG00000063130 +70407 2310061G22Rik MGI:MGI:1917657 +70408 Polr3f MGI:MGI:1924086|Ensembl:ENSMUSG00000027427|Vega:OTTMUSG00000004234 +70409 2310066F23Rik MGI:MGI:1917659 +70410 2610024D14Rik MGI:MGI:1917660 +70412 2900002J02Rik MGI:MGI:1917662 +70415 Stk26 MGI:MGI:1917665|Ensembl:ENSMUSG00000031112|Vega:OTTMUSG00000017475 +70417 Megf10 MGI:MGI:2685177|Ensembl:ENSMUSG00000024593|Vega:OTTMUSG00000024354 +70419 2810408A11Rik MGI:MGI:1917669|Ensembl:ENSMUSG00000018570|Vega:OTTMUSG00000006031 +70420 Arpin MGI:MGI:1917670|Ensembl:ENSMUSG00000039043|Vega:OTTMUSG00000023196 +70422 Ints2 MGI:MGI:1917672|Ensembl:ENSMUSG00000018068|Vega:OTTMUSG00000001206 +70423 Tspan15 MGI:MGI:1917673|Ensembl:ENSMUSG00000037031 +70425 Csnk1g3 MGI:MGI:1917675|Ensembl:ENSMUSG00000073563 +70426 Tekt5 MGI:MGI:1917676|Ensembl:ENSMUSG00000039179|Vega:OTTMUSG00000025761 +70427 Mier2 MGI:MGI:1917677|Ensembl:ENSMUSG00000042570|Vega:OTTMUSG00000035139 +70428 Polr3b MGI:MGI:1917678|Ensembl:ENSMUSG00000034453|Vega:OTTMUSG00000063526 +70430 Tbce MGI:MGI:1917680|Ensembl:ENSMUSG00000039233|Vega:OTTMUSG00000035030 +70432 Rufy2 MGI:MGI:1917682|Ensembl:ENSMUSG00000020070|Vega:OTTMUSG00000030840 +70433 Draxin MGI:MGI:1917683|Ensembl:ENSMUSG00000029005|Vega:OTTMUSG00000010940 +70434 2610201A13Rik MGI:MGI:1917684 +70435 Inf2 MGI:MGI:1917685|Ensembl:ENSMUSG00000037679 +70439 Taf15 MGI:MGI:1917689|Ensembl:ENSMUSG00000020680|Vega:OTTMUSG00000000917 +70441 Mir124-2hg MGI:MGI:1917691|Ensembl:ENSMUSG00000100252 +70443 2610300A13Rik MGI:MGI:1917693 +70445 Cd248 MGI:MGI:1917695|Ensembl:ENSMUSG00000056481 +70448 Atad3aos MGI:MGI:1917698|Ensembl:ENSMUSG00000054514 +70449 2610209C05Rik MGI:MGI:1917699 +70450 Unc13d MGI:MGI:1917700|Ensembl:ENSMUSG00000057948|Vega:OTTMUSG00000003687 +70451 Dhrs13 MGI:MGI:1917701|Ensembl:ENSMUSG00000020834|Vega:OTTMUSG00000000077 +70453 2610105M22Rik MGI:MGI:1917703 +70454 Cenpl MGI:MGI:1917704|Ensembl:ENSMUSG00000026708|Vega:OTTMUSG00000022157 +70456 Mpc2 MGI:MGI:1917706|Ensembl:ENSMUSG00000026568|Vega:OTTMUSG00000022567 +70457 2610303G11Rik MGI:MGI:1917707 +70458 2610318N02Rik MGI:MGI:1917708|Ensembl:ENSMUSG00000049916|Vega:OTTMUSG00000060064 +70459 2610303A01Rik MGI:MGI:1917709 +70460 2610306O10Rik MGI:MGI:1917710 +70461 Crtc3 MGI:MGI:1917711|Ensembl:ENSMUSG00000030527|Vega:OTTMUSG00000027172 +70464 2610312I10Rik MGI:MGI:1917714 +70465 Wdr77 MGI:MGI:1917715|Ensembl:ENSMUSG00000000561|Vega:OTTMUSG00000027092 +70466 Ckap2l MGI:MGI:1917716|Ensembl:ENSMUSG00000048327|Vega:OTTMUSG00000015411 +70469 2610311E24Rik MGI:MGI:1917719 +70470 Rprd1b MGI:MGI:1917720|Ensembl:ENSMUSG00000027651|Vega:OTTMUSG00000015886 +70471 2610304O13Rik MGI:MGI:1917721 +70472 Atad2 MGI:MGI:1917722|Ensembl:ENSMUSG00000022360 +70474 5730405A10Rik MGI:MGI:1917724 +70475 5730409N16Rik MGI:MGI:1917725 +70477 5730407O05Rik MGI:MGI:1917727 +70478 Mipep MGI:MGI:1917728|Ensembl:ENSMUSG00000021993 +70480 5730407M17Rik MGI:MGI:1917730 +70481 Pnma1 MGI:MGI:2180564|Ensembl:ENSMUSG00000054383|Vega:OTTMUSG00000037648 +70482 5730405A17Rik MGI:MGI:1917732 +70484 Slc35d2 MGI:MGI:1917734|Ensembl:ENSMUSG00000033114 +70485 5730409N24Rik MGI:MGI:1917735 +70487 5730403I07Rik MGI:MGI:1917737|Ensembl:ENSMUSG00000099170 +70488 5730405O12Rik MGI:MGI:1917738 +70489 5730405O15Rik MGI:MGI:1917739|Ensembl:ENSMUSG00000087424 +70491 5730412P04Rik MGI:MGI:1917741|Ensembl:ENSMUSG00000087553 +70494 5730409K12Rik MGI:MGI:1917744 +70495 Atp6ap2 MGI:MGI:1917745|Ensembl:ENSMUSG00000031007|Vega:OTTMUSG00000016967 +70496 5730406E14Rik MGI:MGI:1917746 +70497 Arhgap17 MGI:MGI:1917747|Ensembl:ENSMUSG00000030766|Vega:OTTMUSG00000058125 +70499 5730409L17Rik MGI:MGI:1917749 +70503 Ddo MGI:MGI:1925528|Ensembl:ENSMUSG00000063428|Vega:OTTMUSG00000063434 +70507 5730411F24Rik MGI:MGI:1917757 +70508 Bbx MGI:MGI:1917758|Ensembl:ENSMUSG00000022641|Vega:OTTMUSG00000017264 +70509 5730405N03Rik MGI:MGI:1917759 +70510 Rnf167 MGI:MGI:1917760|Ensembl:ENSMUSG00000040746|Vega:OTTMUSG00000006073 +70511 Eef2kmt MGI:MGI:1917761|Ensembl:ENSMUSG00000022544|Vega:OTTMUSG00000028227 +70515 5730407I07Rik MGI:MGI:1917765 +70516 5730408A14Rik MGI:MGI:1917766 +70517 5730410E19Rik MGI:MGI:1917767 +70521 5730420F10Rik MGI:MGI:1917771 +70522 5730415C11Rik MGI:MGI:1917772 +70523 5730420D15Rik MGI:MGI:1917773|Ensembl:ENSMUSG00000097766 +70524 5730414N17Rik MGI:MGI:1917774 +70527 Stambp MGI:MGI:1917777|Ensembl:ENSMUSG00000006906|Vega:OTTMUSG00000058007 +70530 Lrfn2 MGI:MGI:1917780|Ensembl:ENSMUSG00000040490|Vega:OTTMUSG00000014931 +70532 5730433K22Rik MGI:MGI:1917782 +70533 Btf3l4 MGI:MGI:1915312|Ensembl:ENSMUSG00000028568|Vega:OTTMUSG00000008248 +70536 Qpct MGI:MGI:1917786|Ensembl:ENSMUSG00000024084 +70537 5730419F03Rik MGI:MGI:1917787 +70538 5730435O14Rik MGI:MGI:1917788|Ensembl:ENSMUSG00000091370 +70544 Tmem242 MGI:MGI:1917794|Ensembl:ENSMUSG00000004945|Vega:OTTMUSG00000045084 +70545 5730433N10Rik MGI:MGI:1917795 +70546 Zdhhc2 MGI:MGI:1923452|Ensembl:ENSMUSG00000039470|Vega:OTTMUSG00000026075 +70548 5730437C12Rik MGI:MGI:1917798 +70549 Tln2 MGI:MGI:1917799|Ensembl:ENSMUSG00000052698|Vega:OTTMUSG00000062653 +70550 5730416F02Rik MGI:MGI:1917800|Ensembl:ENSMUSG00000081793 +70551 Tmtc4 MGI:MGI:1921050|Ensembl:ENSMUSG00000041594|Vega:OTTMUSG00000025742 +70552 Lrrc56 MGI:MGI:1917802|Ensembl:ENSMUSG00000038637|Vega:OTTMUSG00000023215 +70556 Slc25a33 MGI:MGI:1917806|Ensembl:ENSMUSG00000028982|Vega:OTTMUSG00000010268 +70558 5730437C11Rik MGI:MGI:1917808 +70560 Wars2 MGI:MGI:1917810|Ensembl:ENSMUSG00000004233|Vega:OTTMUSG00000006862 +70561 Txndc16 MGI:MGI:1917811|Ensembl:ENSMUSG00000021830|Vega:OTTMUSG00000025959 +70562 5730419A17Rik MGI:MGI:1917812 +70563 5730453C05Rik MGI:MGI:1917813 +70564 Fam213a MGI:MGI:1917814|Ensembl:ENSMUSG00000021792|Vega:OTTMUSG00000027960 +70567 Fra10ac1 MGI:MGI:1917817|Ensembl:ENSMUSG00000054237 +70568 Cpne3 MGI:MGI:1917818|Ensembl:ENSMUSG00000028228|Vega:OTTMUSG00000004615 +70571 Tcerg1l MGI:MGI:1917821|Ensembl:ENSMUSG00000091002|Vega:OTTMUSG00000033197 +70572 Ipo5 MGI:MGI:1917822|Ensembl:ENSMUSG00000030662 +70573 Tbccd1 MGI:MGI:1917823|Ensembl:ENSMUSG00000004462 +70574 Cpm MGI:MGI:1917824|Ensembl:ENSMUSG00000020183|Vega:OTTMUSG00000031908 +70575 Gfod2 MGI:MGI:1917825|Ensembl:ENSMUSG00000013150|Vega:OTTMUSG00000032830 +70577 5730448F11Rik MGI:MGI:1917827 +70579 Zc3h11a MGI:MGI:1917829|Ensembl:ENSMUSG00000102976|Vega:OTTMUSG00000049664 +70580 5730478J17Rik MGI:MGI:1917830 +70584 Pak4 MGI:MGI:1917834|Ensembl:ENSMUSG00000030602|Vega:OTTMUSG00000025040 +70591 5730455P16Rik MGI:MGI:1917841|Ensembl:ENSMUSG00000057181|Vega:OTTMUSG00000000223 +70592 5730480H06Rik MGI:MGI:1917842|Ensembl:ENSMUSG00000029089 +70593 Evx1os MGI:MGI:1917843|Ensembl:ENSMUSG00000086126 +70594 5730460C07Rik MGI:MGI:1917844|Ensembl:ENSMUSG00000062046 +70596 5730447C08Rik MGI:MGI:1917846 +70598 Filip1 MGI:MGI:1917848|Ensembl:ENSMUSG00000034898|Vega:OTTMUSG00000036908 +70599 Ssfa2 MGI:MGI:1917849|Ensembl:ENSMUSG00000027007|Vega:OTTMUSG00000013318 +70601 Ecd MGI:MGI:1917851|Ensembl:ENSMUSG00000021810 +70602 5730488B01Rik MGI:MGI:1917852|Ensembl:ENSMUSG00000103995 +70603 Mutyh MGI:MGI:1917853|Ensembl:ENSMUSG00000028687|Vega:OTTMUSG00000009751 +70604 Dnajb14 MGI:MGI:1917854|Ensembl:ENSMUSG00000074212|Vega:OTTMUSG00000022248 +70605 Zdhhc24 MGI:MGI:1917855|Ensembl:ENSMUSG00000006463|Vega:OTTMUSG00000034230 +70609 5730492I20Rik MGI:MGI:1917859 +70611 Fbxo33 MGI:MGI:1917861|Ensembl:ENSMUSG00000035329|Vega:OTTMUSG00000034929 +70612 Tmem230 MGI:MGI:1917862|Ensembl:ENSMUSG00000027341|Vega:OTTMUSG00000015548 +70615 Ankrd24 MGI:MGI:1890394|Ensembl:ENSMUSG00000054708|Vega:OTTMUSG00000030488 +70616 Sugp1 MGI:MGI:1917866|Ensembl:ENSMUSG00000011306|Vega:OTTMUSG00000062213 +70617 5730508B09Rik MGI:MGI:1917867|Ensembl:ENSMUSG00000050549|Vega:OTTMUSG00000052815 +70619 5730510P18Rik MGI:MGI:1917869 +70620 Ube2v2 MGI:MGI:1917870|Ensembl:ENSMUSG00000022674|Vega:OTTMUSG00000025687 +70624 5730507A11Rik MGI:MGI:1917874 +70625 Med26 MGI:MGI:1917875|Ensembl:ENSMUSG00000045248|Vega:OTTMUSG00000062114 +70626 5730522E02Rik MGI:MGI:1917876 +70629 5730512F23Rik MGI:MGI:1917879 +70630 5730493B19Rik MGI:MGI:1917880 +70638 Fam189a1 MGI:MGI:1917888|Ensembl:ENSMUSG00000030518|Vega:OTTMUSG00000031035 +70639 5730521K06Rik MGI:MGI:1917889 +70640 Dcp2 MGI:MGI:1917890|Ensembl:ENSMUSG00000024472|Vega:OTTMUSG00000055564 +70644 5730552O08Rik MGI:MGI:1917894 +70645 Oip5 MGI:MGI:1917895|Ensembl:ENSMUSG00000072980|Vega:OTTMUSG00000015949 +70646 Naa30 MGI:MGI:1922259|Ensembl:ENSMUSG00000036282|Vega:OTTMUSG00000032783 +70649 5730575I04Rik MGI:MGI:1917899 +70650 Zcchc8 MGI:MGI:1917900|Ensembl:ENSMUSG00000029427|Vega:OTTMUSG00000054725 +70652 Tmem144 MGI:MGI:1917902|Ensembl:ENSMUSG00000027956|Vega:OTTMUSG00000052194 +70656 5730526G10Rik MGI:MGI:1917906 +70661 Sik3 MGI:MGI:2446296|Ensembl:ENSMUSG00000034135|Vega:OTTMUSG00000028702 +70673 Prdm16 MGI:MGI:1917923|Ensembl:ENSMUSG00000039410|Vega:OTTMUSG00000010585 +70675 Vcpip1 MGI:MGI:1917925|Ensembl:ENSMUSG00000045210|Vega:OTTMUSG00000022113 +70676 Gulp1 MGI:MGI:1920407|Ensembl:ENSMUSG00000056870|Vega:OTTMUSG00000030324 +70680 3021401N23Rik MGI:MGI:1917930 +70681 Abraxas1 MGI:MGI:1917931|Ensembl:ENSMUSG00000035234|Vega:OTTMUSG00000026778 +70683 Utp20 MGI:MGI:1917933|Ensembl:ENSMUSG00000004356 +70685 3830408D07Rik MGI:MGI:1917935 +70686 Dusp16 MGI:MGI:1917936|Ensembl:ENSMUSG00000030203|Vega:OTTMUSG00000023267 +70691 3830403N18Rik MGI:MGI:1917941|Ensembl:ENSMUSG00000031125|Vega:OTTMUSG00000017493 +70693 Adgra3 MGI:MGI:1917943|Ensembl:ENSMUSG00000029090|Vega:OTTMUSG00000054525 +70696 3830417A13Rik MGI:MGI:1917946|Ensembl:ENSMUSG00000031179|Vega:OTTMUSG00000017599 +70699 Nup205 MGI:MGI:2141625|Ensembl:ENSMUSG00000038759|Vega:OTTMUSG00000056108 +70700 3021401L19Rik MGI:MGI:1917950 +70701 Nipal1 MGI:MGI:1917951|Ensembl:ENSMUSG00000067219|Vega:OTTMUSG00000054646 +70708 3830422I06Rik MGI:MGI:1917958 +70713 Gpr137c MGI:MGI:1917963|Ensembl:ENSMUSG00000049092|Vega:OTTMUSG00000025982 +70715 6330405D24Rik MGI:MGI:1917965 +70716 6330406O05Rik MGI:MGI:1917966 +70717 Medag MGI:MGI:1917967|Ensembl:ENSMUSG00000029659|Vega:OTTMUSG00000026847 +70719 Arhgap45 MGI:MGI:1917969|Ensembl:ENSMUSG00000035697|Vega:OTTMUSG00000019131 +70720 6330407A03Rik MGI:MGI:1917970 +70725 6330411D24Rik MGI:MGI:1917975 +70726 Angptl6 MGI:MGI:1917976|Ensembl:ENSMUSG00000038742|Vega:OTTMUSG00000042075 +70727 Rasgef1a MGI:MGI:1917977|Ensembl:ENSMUSG00000030134|Vega:OTTMUSG00000056768 +70729 Nos1ap MGI:MGI:1917979|Ensembl:ENSMUSG00000038473|Vega:OTTMUSG00000029837 +70730 6330409D20Rik MGI:MGI:1917980|Ensembl:ENSMUSG00000009551|Vega:OTTMUSG00000012533 +70733 6330411E07Rik MGI:MGI:1917983 +70735 6330403N20Rik MGI:MGI:1917985 +70737 Cgn MGI:MGI:1927237|Ensembl:ENSMUSG00000068876|Vega:OTTMUSG00000019660 +70744 6330403L08Rik MGI:MGI:1917994 +70745 6330418B08Rik MGI:MGI:1917995 +70747 Tspan2 MGI:MGI:1917997|Ensembl:ENSMUSG00000027858|Vega:OTTMUSG00000026566 +70749 6330408M09Rik MGI:MGI:1917999 +70750 Kdsr MGI:MGI:1918000|Ensembl:ENSMUSG00000009905|Vega:OTTMUSG00000048603 +70753 6330415B21Rik MGI:MGI:1918003|Ensembl:ENSMUSG00000108077 +70757 Hacd2 MGI:MGI:1918007|Ensembl:ENSMUSG00000035376 +70760 6330417A16Rik MGI:MGI:1918010 +70762 Dclk2 MGI:MGI:1918012|Ensembl:ENSMUSG00000028078|Vega:OTTMUSG00000051762 +70763 6330419E04Rik MGI:MGI:1918013 +70767 Prpf3 MGI:MGI:1918017|Ensembl:ENSMUSG00000015748|Vega:OTTMUSG00000030680 +70769 Nolc1 MGI:MGI:1918019|Ensembl:ENSMUSG00000015176 +70771 Gpr173 MGI:MGI:1918021|Ensembl:ENSMUSG00000056679|Vega:OTTMUSG00000019707 +70772 Ggnbp1 MGI:MGI:3055306|Ensembl:ENSMUSG00000048731|Vega:OTTMUSG00000031014 +70779 Prdm5 MGI:MGI:1918029|Ensembl:ENSMUSG00000029913|Vega:OTTMUSG00000036961 +70782 4631402F24Rik MGI:MGI:1918032 +70784 Rasl12 MGI:MGI:1918034|Ensembl:ENSMUSG00000041696|Vega:OTTMUSG00000062628 +70785 Dennd1c MGI:MGI:1918035|Ensembl:ENSMUSG00000002668 +70788 Klhl30 MGI:MGI:1918038|Ensembl:ENSMUSG00000026308|Vega:OTTMUSG00000026754 +70789 Kynu MGI:MGI:1918039|Ensembl:ENSMUSG00000026866|Vega:OTTMUSG00000012317 +70790 Ubr5 MGI:MGI:1918040|Ensembl:ENSMUSG00000037487 +70791 Hars2 MGI:MGI:1918041|Ensembl:ENSMUSG00000019143|Vega:OTTMUSG00000033867 +70793 Gm9725 MGI:MGI:3646552 +70796 Zdhhc1 MGI:MGI:1918046|Ensembl:ENSMUSG00000039199|Vega:OTTMUSG00000062047 +70797 Ankib1 MGI:MGI:1918047|Ensembl:ENSMUSG00000040351|Vega:OTTMUSG00000052985 +70798 4631422I05Rik MGI:MGI:1918048 +70799 Cep192 MGI:MGI:1918049|Ensembl:ENSMUSG00000024542 +70800 4631405K08Rik MGI:MGI:1918050 +70802 Pwwp2a MGI:MGI:1918052|Ensembl:ENSMUSG00000044950|Vega:OTTMUSG00000005461 +70804 Pgrmc2 MGI:MGI:1918054|Ensembl:ENSMUSG00000049940|Vega:OTTMUSG00000023698 +70807 Arrdc2 MGI:MGI:1918057|Ensembl:ENSMUSG00000002910|Vega:OTTMUSG00000061580 +70808 4632415L05Rik MGI:MGI:1918058|Ensembl:ENSMUSG00000048106 +70809 Clec2g MGI:MGI:1918059|Ensembl:ENSMUSG00000000248|Vega:OTTMUSG00000028623 +70810 Krt25 MGI:MGI:1918060|Ensembl:ENSMUSG00000035831|Vega:OTTMUSG00000006453 +70814 4921506L19Rik MGI:MGI:1918064 +70817 4633402D09Rik MGI:MGI:1918067 +70821 4921507P07Rik MGI:MGI:1918071|Ensembl:ENSMUSG00000029828|Vega:OTTMUSG00000036739 +70823 Hmgxb4 MGI:MGI:1918073|Ensembl:ENSMUSG00000034518|Vega:OTTMUSG00000017305 +70824 4921504P20Rik MGI:MGI:1918074 +70825 4633401L03Rik MGI:MGI:1918075 +70827 Trak2 MGI:MGI:1918077|Ensembl:ENSMUSG00000026028|Vega:OTTMUSG00000037699 +70828 4633401B06Rik MGI:MGI:1918078 +70829 Ccdc93 MGI:MGI:1918079|Ensembl:ENSMUSG00000026339|Vega:OTTMUSG00000021024 +70831 Krtap31-1 MGI:MGI:1918081|Ensembl:ENSMUSG00000070334|Vega:OTTMUSG00000002190 +70832 4921504A21Rik MGI:MGI:1918082|Ensembl:ENSMUSG00000097626 +70833 4733401A01Rik MGI:MGI:1918083 +70834 Spag9 MGI:MGI:1918084|Ensembl:ENSMUSG00000020859|Vega:OTTMUSG00000001645 +70835 Prss22 MGI:MGI:1918085|Ensembl:ENSMUSG00000045027 +70838 4921507H08Rik MGI:MGI:1918088 +70839 P2ry12 MGI:MGI:1918089|Ensembl:ENSMUSG00000036353|Vega:OTTMUSG00000052355 +70840 Slc22a16 MGI:MGI:1918090|Ensembl:ENSMUSG00000019834|Vega:OTTMUSG00000024011 +70843 Krt28 MGI:MGI:1918093|Ensembl:ENSMUSG00000055937|Vega:OTTMUSG00000004971 +70844 4921508M14Rik MGI:MGI:1918094 +70845 4921508D12Rik MGI:MGI:1918095|Ensembl:ENSMUSG00000027345 +70846 Ttc6 MGI:MGI:2684915|Ensembl:ENSMUSG00000046782|Vega:OTTMUSG00000037594 +70847 4733401D01Rik MGI:MGI:1918097 +70850 4921504P05Rik MGI:MGI:1918100 +70852 Alkbh3os1 MGI:MGI:1918102|Ensembl:ENSMUSG00000027196 +70853 Vwa3b MGI:MGI:1918103|Ensembl:ENSMUSG00000050122|Vega:OTTMUSG00000029372 +70857 4921509J17Rik MGI:MGI:1918107 +70858 4921511I17Rik MGI:MGI:1918108|Ensembl:ENSMUSG00000114136 +70859 Lrrc63 MGI:MGI:1918109|Ensembl:ENSMUSG00000021997|Vega:OTTMUSG00000042844 +70861 Akr1cl MGI:MGI:1918111|Ensembl:ENSMUSG00000025955|Vega:OTTMUSG00000030348 +70862 Spata16 MGI:MGI:1918112|Ensembl:ENSMUSG00000039335|Vega:OTTMUSG00000022026 +70864 Fam47c MGI:MGI:1918114|Ensembl:ENSMUSG00000078315|Vega:OTTMUSG00000017883 +70866 Slco6d1 MGI:MGI:1918116|Ensembl:ENSMUSG00000026336|Vega:OTTMUSG00000029690 +70867 4921521D15Rik MGI:MGI:1918117 +70868 4921515L22Rik MGI:MGI:1918118 +70869 4921522A10Rik MGI:MGI:1918119 +70870 4921516I12Rik MGI:MGI:1918120 +70871 4921517O11Rik MGI:MGI:1918121 +70872 4921519G19Rik MGI:MGI:1918122 +70873 Cnbd2 MGI:MGI:1918123|Ensembl:ENSMUSG00000038085|Vega:OTTMUSG00000016084 +70874 4921513I03Rik MGI:MGI:1918124|Ensembl:ENSMUSG00000044544 +70875 4921513I08Rik MGI:MGI:1918125 +70876 4921517D16Rik MGI:MGI:1918126 +70879 4921511E18Rik MGI:MGI:1918129 +70880 4921525D07Rik MGI:MGI:1918130 +70881 Nt5c1b MGI:MGI:1918131|Ensembl:ENSMUSG00000020622|Vega:OTTMUSG00000027551 +70882 Armc3 MGI:MGI:1918132|Ensembl:ENSMUSG00000037683|Vega:OTTMUSG00000011475 +70883 4921509A06Rik MGI:MGI:1918133 +70884 Ccdc81 MGI:MGI:1918134|Ensembl:ENSMUSG00000039391|Vega:OTTMUSG00000029110 +70885 Ints10 MGI:MGI:1918135|Ensembl:ENSMUSG00000031864|Vega:OTTMUSG00000023543 +70886 4921515E04Rik MGI:MGI:1918136 +70887 Dmrtc1a MGI:MGI:1918137|Ensembl:ENSMUSG00000031323|Vega:OTTMUSG00000018182 +70888 4921521C08Rik MGI:MGI:1918138 +70890 4921524M04Rik MGI:MGI:1918140 +70891 Spdya MGI:MGI:1918141|Ensembl:ENSMUSG00000052525|Vega:OTTMUSG00000033091 +70892 Ttll7 MGI:MGI:1918142|Ensembl:ENSMUSG00000036745|Vega:OTTMUSG00000022681 +70893 Glb1l3 MGI:MGI:1918143|Ensembl:ENSMUSG00000031966|Vega:OTTMUSG00000060285 +70894 Efcab3 MGI:MGI:1918144|Ensembl:ENSMUSG00000020690|Vega:OTTMUSG00000002985 +70895 4921511E07Rik MGI:MGI:1918145 +70896 Speer1 MGI:MGI:1918146|Ensembl:ENSMUSG00000095829|Vega:OTTMUSG00000036523 +70897 Fam71d MGI:MGI:1918147|Ensembl:ENSMUSG00000056987|Vega:OTTMUSG00000036500 +70898 Slain1os MGI:MGI:1918148|Ensembl:ENSMUSG00000089707 +70900 4921517D22Rik MGI:MGI:1918150|Ensembl:ENSMUSG00000049902 +70901 4921524L21Rik MGI:MGI:1918151|Ensembl:ENSMUSG00000039540 +70902 Lpcat2b MGI:MGI:1918152|Ensembl:ENSMUSG00000033794|Vega:OTTMUSG00000036579 +70904 4921515G04Rik MGI:MGI:1918154 +70906 4921522E08Rik MGI:MGI:1918156 +70909 4921504E06Rik MGI:MGI:1918087|Ensembl:ENSMUSG00000026734|Vega:OTTMUSG00000011523 +70911 Phyhipl MGI:MGI:1918161|Ensembl:ENSMUSG00000037747|Vega:OTTMUSG00000034155 +70912 Nckap5los MGI:MGI:1918162 +70913 4921523L03Rik MGI:MGI:1918163 +70917 4921509O07Rik MGI:MGI:1918167 +70918 Nsun7 MGI:MGI:1918168|Ensembl:ENSMUSG00000029206|Vega:OTTMUSG00000024413 +70919 4921520J07Rik MGI:MGI:1918169 +70920 Tex47 MGI:MGI:1918170|Ensembl:ENSMUSG00000040514|Vega:OTTMUSG00000033444 +70924 4921511C10Rik MGI:MGI:1918174|Ensembl:ENSMUSG00000104585 +70925 Cdkn2aip MGI:MGI:1918175|Ensembl:ENSMUSG00000038069|Vega:OTTMUSG00000061820 +70926 4921523P09Rik MGI:MGI:1918176 +70928 Trim69 MGI:MGI:1918178|Ensembl:ENSMUSG00000033368|Vega:OTTMUSG00000015535 +70929 4921527H02Rik MGI:MGI:1918179 +70930 Nol8 MGI:MGI:1918180|Ensembl:ENSMUSG00000021392 +70931 4921534E14Rik MGI:MGI:1918181 +70933 4931402G19Rik MGI:MGI:1918183 +70934 4931403G20Rik MGI:MGI:1918184 +70935 Speer4f1 MGI:MGI:1918185|Ensembl:ENSMUSG00000058643|Vega:OTTMUSG00000026690 +70936 4931400O07Rik MGI:MGI:1918186|Ensembl:ENSMUSG00000031194|Vega:OTTMUSG00000017638 +70941 4921539E11Rik MGI:MGI:1918191|Ensembl:ENSMUSG00000028520|Vega:OTTMUSG00000008068 +70942 4931403E22Rik MGI:MGI:1918192|Ensembl:ENSMUSG00000093772 +70945 Mmrn1 MGI:MGI:1918195|Ensembl:ENSMUSG00000054641|Vega:OTTMUSG00000034145 +70948 Wdr20rt MGI:MGI:1918198|Ensembl:ENSMUSG00000035560 +70950 Ccdc178 MGI:MGI:1918200|Ensembl:ENSMUSG00000024306 +70951 Spata1 MGI:MGI:1918201|Ensembl:ENSMUSG00000028188|Vega:OTTMUSG00000022271 +70952 Poteg MGI:MGI:1918202|Ensembl:ENSMUSG00000063932|Ensembl:ENSMUSG00000110333|Vega:OTTMUSG00000061080|Vega:OTTMUSG00000061081 +70954 4922502B01Rik MGI:MGI:1918204 +70955 4931403M11Rik MGI:MGI:1918205 +70956 Tex19.2 MGI:MGI:1918206|Ensembl:ENSMUSG00000039337|Vega:OTTMUSG00000004292 +70957 Stamos MGI:MGI:1918207|Ensembl:ENSMUSG00000086657 +70960 4921531P14Rik MGI:MGI:1918210 +70961 4921532D01Rik MGI:MGI:1918211 +70962 4922502N22Rik MGI:MGI:1918212|Ensembl:ENSMUSG00000108128 +70963 4931402H11Rik MGI:MGI:1918213 +70964 4931418L13Rik MGI:MGI:1918214 +70966 4931415C17Rik MGI:MGI:1918216|Ensembl:ENSMUSG00000054910 +70967 Eva1c MGI:MGI:1918217|Ensembl:ENSMUSG00000039903|Vega:OTTMUSG00000019912 +70968 4931407J08Rik MGI:MGI:1918218 +70969 4930500F04Rik MGI:MGI:1922182|Ensembl:ENSMUSG00000107214 +70970 4931419H13Rik MGI:MGI:1918220|Ensembl:ENSMUSG00000106589 +70971 4931429P17Rik MGI:MGI:1918221|Ensembl:ENSMUSG00000047324 +70972 4931420L22Rik MGI:MGI:1918222 +70973 4931431B13Rik MGI:MGI:1918223|Ensembl:ENSMUSG00000108354 +70974 Pgm2l1 MGI:MGI:1918224|Ensembl:ENSMUSG00000030729|Vega:OTTMUSG00000032728 +70976 Ccdc105 MGI:MGI:1918226|Ensembl:ENSMUSG00000078442 +70977 Cabs1 MGI:MGI:1918227|Ensembl:ENSMUSG00000007907|Vega:OTTMUSG00000022058 +70979 Fancd2os MGI:MGI:1918229|Ensembl:ENSMUSG00000033963|Vega:OTTMUSG00000023491 +70980 Ubqln5 MGI:MGI:1918230|Ensembl:ENSMUSG00000055643|Vega:OTTMUSG00000019039 +70981 4931423N10Rik MGI:MGI:1918231|Ensembl:ENSMUSG00000026774|Vega:OTTMUSG00000012055 +70983 4931409D07Rik MGI:MGI:1918233 +70984 4931406C07Rik MGI:MGI:1918234|Ensembl:ENSMUSG00000031938|Vega:OTTMUSG00000062263 +70985 4931406E20Rik MGI:MGI:1918235 +70986 4931422A03Rik MGI:MGI:1918236 +70987 4931413K12Rik MGI:MGI:1918237 +70988 4931428L18Rik MGI:MGI:1918238|Ensembl:ENSMUSG00000086727|Vega:OTTMUSG00000026557 +70989 Jhy MGI:MGI:1918239|Ensembl:ENSMUSG00000032023|Vega:OTTMUSG00000034173 +70991 4931432E15Rik MGI:MGI:1918241 +70992 4931407E12Rik MGI:MGI:1918242 +70993 Prss54 MGI:MGI:1918243|Ensembl:ENSMUSG00000048400|Vega:OTTMUSG00000061765 +70995 4931412I15Rik MGI:MGI:1918245 +70997 Spef1 MGI:MGI:3513546|Ensembl:ENSMUSG00000027329|Vega:OTTMUSG00000015912 +70998 Phf6 MGI:MGI:1918248|Ensembl:ENSMUSG00000025626|Vega:OTTMUSG00000017343 +70999 Naa40 MGI:MGI:1918249|Ensembl:ENSMUSG00000024764 +71000 4931440J10Rik MGI:MGI:1918250|Ensembl:ENSMUSG00000097775 +71001 Mgat4e MGI:MGI:1918251|Ensembl:ENSMUSG00000046367|Vega:OTTMUSG00000037371 +71003 Prss41 MGI:MGI:1918253|Ensembl:ENSMUSG00000024114|Vega:OTTMUSG00000028089 +71004 4931440P22Rik MGI:MGI:1918254|Ensembl:ENSMUSG00000074580 +71006 4932703K07Rik MGI:MGI:1918256 +71007 D7Ertd443e MGI:MGI:1196431|Ensembl:ENSMUSG00000030994|Vega:OTTMUSG00000038090 +71008 4933401D09Rik MGI:MGI:1918258 +71009 4933407I08Rik MGI:MGI:1918259 +71011 4933401B06Rik MGI:MGI:1918261|Ensembl:ENSMUSG00000055700 +71017 4933407E14Rik MGI:MGI:1918267 +71018 4933404K13Rik MGI:MGI:1918268|Ensembl:ENSMUSG00000111342 +71020 Spats1 MGI:MGI:1918270|Ensembl:ENSMUSG00000023935 +71021 4933403J19Rik MGI:MGI:1918271 +71023 4933407C09Rik MGI:MGI:1918273 +71025 4933402C05Rik MGI:MGI:1918275 +71026 Speer3 MGI:MGI:1918276|Ensembl:ENSMUSG00000067855|Vega:OTTMUSG00000032782 +71027 Tmem30c MGI:MGI:1918277|Ensembl:ENSMUSG00000022753|Vega:OTTMUSG00000028559 +71029 4933402C06Rik MGI:MGI:1918279|Ensembl:ENSMUSG00000102004 +71030 4933403O08Rik MGI:MGI:1918280|Ensembl:ENSMUSG00000079460|Vega:OTTMUSG00000018440 +71032 4933403L11Rik MGI:MGI:1918282 +71033 4933406K04Rik MGI:MGI:1918283|Ensembl:ENSMUSG00000085820 +71037 Prss55 MGI:MGI:1918287|Ensembl:ENSMUSG00000034623|Vega:OTTMUSG00000036311 +71038 4933401H06Rik MGI:MGI:1918288|Ensembl:ENSMUSG00000106306 +71040 4933406B17Rik MGI:MGI:1918290|Ensembl:ENSMUSG00000110427 +71041 Pcgf6 MGI:MGI:1918291|Ensembl:ENSMUSG00000025050 +71042 4933401J01Rik MGI:MGI:1918292 +71045 4933406I18Rik MGI:MGI:1918295|Ensembl:ENSMUSG00000087475 +71046 4933405L10Rik MGI:MGI:1918296|Ensembl:ENSMUSG00000013158|Vega:OTTMUSG00000062056 +71050 4933404I11Rik MGI:MGI:1918300 +71051 4933401L05Rik MGI:MGI:1918301 +71052 4933400B14Rik MGI:MGI:1918302 +71054 Ppp2r2cos MGI:MGI:1918304|Ensembl:ENSMUSG00000087487 +71056 4933405E24Rik MGI:MGI:1918306|Ensembl:ENSMUSG00000086209 +71057 4933402J10Rik MGI:MGI:1918307|Ensembl:ENSMUSG00000106013 +71058 4933400L20Rik MGI:MGI:1918308|Ensembl:ENSMUSG00000110336 +71059 Hexim2 MGI:MGI:1918309|Ensembl:ENSMUSG00000043372|Vega:OTTMUSG00000002961 +71062 Tekt3 MGI:MGI:1918312|Ensembl:ENSMUSG00000042189|Vega:OTTMUSG00000005882 +71063 Zfp597 MGI:MGI:1918313|Ensembl:ENSMUSG00000039789|Vega:OTTMUSG00000026609 +71064 4933406B15Rik MGI:MGI:1918314 +71065 4933407O12Rik MGI:MGI:1918315 +71066 Hsfy2 MGI:MGI:1918316|Ensembl:ENSMUSG00000045336|Vega:OTTMUSG00000047042 +71067 4933411E08Rik MGI:MGI:1918317|Ensembl:ENSMUSG00000112500 +71069 Stox2 MGI:MGI:1918319|Ensembl:ENSMUSG00000038143|Vega:OTTMUSG00000061347 +71071 4933412O06Rik MGI:MGI:1918321|Ensembl:ENSMUSG00000113960 +71076 4933422E07Rik MGI:MGI:1918326 +71077 4933423N12Rik MGI:MGI:1918327 +71078 Adam30 MGI:MGI:1918328|Ensembl:ENSMUSG00000043468|Vega:OTTMUSG00000053244 +71080 Sox5os1 MGI:MGI:1918330 +71081 4933416E03Rik MGI:MGI:1918331|Ensembl:ENSMUSG00000085198 +71082 4933416M07Rik MGI:MGI:1918332 +71083 Dmrtc1c1 MGI:MGI:1918333|Ensembl:ENSMUSG00000067562|Vega:OTTMUSG00000018178 +71084 4933409D19Rik MGI:MGI:1918334 +71085 Arhgap19 MGI:MGI:1918335|Ensembl:ENSMUSG00000025154|Vega:OTTMUSG00000042088 +71086 4933412E12Rik MGI:MGI:1918336|Ensembl:ENSMUSG00000112627 +71087 4933409K08Rik MGI:MGI:1918337 +71088 4933412E24Rik MGI:MGI:1918338|Ensembl:ENSMUSG00000071749 +71089 Sept12 MGI:MGI:1918339|Ensembl:ENSMUSG00000022542 +71090 4933411G06Rik MGI:MGI:1918340|Ensembl:ENSMUSG00000062224|Vega:OTTMUSG00000033685 +71091 Cdkl1 MGI:MGI:1918341|Ensembl:ENSMUSG00000020990 +71092 4930452A19Rik MGI:MGI:1925363 +71093 Atoh8 MGI:MGI:1918343|Ensembl:ENSMUSG00000037621|Vega:OTTMUSG00000057917 +71096 Sntg1 MGI:MGI:1918346|Ensembl:ENSMUSG00000025909|Vega:OTTMUSG00000033160 +71097 4933421A08Rik MGI:MGI:1918347 +71099 Tssk4 MGI:MGI:1918349|Ensembl:ENSMUSG00000007591 +71100 4933413L06Rik MGI:MGI:1918350|Ensembl:ENSMUSG00000079048 +71101 Uvssa MGI:MGI:1918351|Ensembl:ENSMUSG00000037355|Vega:OTTMUSG00000028632 +71103 Glt6d1 MGI:MGI:1918353|Ensembl:ENSMUSG00000036401|Vega:OTTMUSG00000012628 +71106 4933413J09Rik MGI:MGI:1918356|Ensembl:ENSMUSG00000021874 +71107 4933423L19Rik MGI:MGI:1918357 +71111 Gpr39 MGI:MGI:1918361|Ensembl:ENSMUSG00000026343|Vega:OTTMUSG00000030266 +71113 4933424H11Rik MGI:MGI:1918363 +71116 Stx18 MGI:MGI:1918366|Ensembl:ENSMUSG00000029125|Vega:OTTMUSG00000023041 +71120 1700022A22Rik MGI:MGI:1922807|Ensembl:ENSMUSG00000099751 +71121 4933407I18Rik MGI:MGI:1918371 +71122 4933408N05Rik MGI:MGI:1918372 +71123 4933411B09Rik MGI:MGI:1918373 +71125 4933407G14Rik MGI:MGI:1918375 +71127 4933425E08Rik MGI:MGI:1918377 +71128 4933417C20Rik MGI:MGI:1918378 +71130 Sh2d6 MGI:MGI:1918380|Ensembl:ENSMUSG00000052631|Vega:OTTMUSG00000034307 +71131 Zfp689 MGI:MGI:1918381|Ensembl:ENSMUSG00000048921|Vega:OTTMUSG00000022492 +71132 Cabyr MGI:MGI:1918382|Ensembl:ENSMUSG00000024430|Vega:OTTMUSG00000030149 +71133 4933422A05Rik MGI:MGI:1918383|Ensembl:ENSMUSG00000111746 +71134 4933417E11Rik MGI:MGI:1918384|Ensembl:ENSMUSG00000101848 +71135 4933411O13Rik MGI:MGI:1918385 +71137 Rfx4 MGI:MGI:1918387|Ensembl:ENSMUSG00000020037|Vega:OTTMUSG00000037132 +71138 Tmem217 MGI:MGI:3646280|Ensembl:ENSMUSG00000079580|Ensembl:ENSMUSG00000091614 +71139 4933408K01Rik MGI:MGI:1918389 +71140 4933413I22Rik MGI:MGI:1918390 +71141 4933407L21Rik MGI:MGI:1918391|Ensembl:ENSMUSG00000026224|Vega:OTTMUSG00000033909 +71143 4933424L07Rik MGI:MGI:1918393 +71145 Scara5 MGI:MGI:1918395|Ensembl:ENSMUSG00000022032|Vega:OTTMUSG00000027832 +71146 Golga7b MGI:MGI:1918396|Ensembl:ENSMUSG00000042532|Vega:OTTMUSG00000028389 +71147 Oxsm MGI:MGI:1918397|Ensembl:ENSMUSG00000021786|Vega:OTTMUSG00000023282 +71148 Mier1 MGI:MGI:1918398|Ensembl:ENSMUSG00000028522|Vega:OTTMUSG00000008075 +71149 4933413G19Rik MGI:MGI:1918399|Ensembl:ENSMUSG00000079304|Vega:OTTMUSG00000023765 +71151 Eri2 MGI:MGI:1918401|Ensembl:ENSMUSG00000030929|Vega:OTTMUSG00000025656 +71153 4933417O13Rik MGI:MGI:1918403|Ensembl:ENSMUSG00000101360 +71154 4933426K07Rik MGI:MGI:1918404 +71155 4933424C09Rik MGI:MGI:1918405 +71156 Lrrc72 MGI:MGI:1920830|Ensembl:ENSMUSG00000020545|Vega:OTTMUSG00000027602 +71157 4933423K11Rik MGI:MGI:1918407 +71158 4933423P22Rik MGI:MGI:1918408 +71159 4933416I08Rik MGI:MGI:1918409|Ensembl:ENSMUSG00000079593|Vega:OTTMUSG00000017378 +71161 Prkag2os1 MGI:MGI:1918411|Ensembl:ENSMUSG00000086446 +71162 4933421I07Rik MGI:MGI:1918412|Ensembl:ENSMUSG00000030463|Vega:OTTMUSG00000037951 +71163 Zfp626 MGI:MGI:1918413|Ensembl:ENSMUSG00000030604|Vega:OTTMUSG00000058144 +71164 Zdhhc11 MGI:MGI:1918414|Ensembl:ENSMUSG00000069189 +71165 4933421D24Rik MGI:MGI:1918415 +71166 4933424G06Rik MGI:MGI:1918416|Ensembl:ENSMUSG00000102416|Vega:OTTMUSG00000049901 +71168 4933421H06Rik MGI:MGI:1918418 +71169 Nbas MGI:MGI:1918419|Ensembl:ENSMUSG00000020576 +71170 4933423N03Rik MGI:MGI:1918420 +71172 4933415J04Rik MGI:MGI:1918422 +71173 4933426B08Rik MGI:MGI:1918423 +71174 4933416M06Rik MGI:MGI:1918424|Ensembl:ENSMUSG00000100733 +71175 Nipbl MGI:MGI:1913976|Ensembl:ENSMUSG00000022141 +71176 Fbxo24 MGI:MGI:1918426|Ensembl:ENSMUSG00000089984|Vega:OTTMUSG00000021962 +71177 Ints13 MGI:MGI:1918427|Ensembl:ENSMUSG00000040250|Vega:OTTMUSG00000023507 +71178 4933415b22rik - +71180 4933416E14Rik MGI:MGI:1918430 +71181 4933411E06Rik MGI:MGI:1918431 +71182 4933417G07Rik MGI:MGI:1918432|Ensembl:ENSMUSG00000106572 +71183 Clec12b MGI:MGI:1918433|Ensembl:ENSMUSG00000030158|Vega:OTTMUSG00000056465 +71184 Usp46os2 MGI:MGI:1924246 +71185 4933424C08Rik MGI:MGI:1918435 +71186 4933417D19Rik MGI:MGI:1918436|Ensembl:ENSMUSG00000097637 +71189 4933426I03Rik MGI:MGI:1918439 +71190 4933425M03Rik MGI:MGI:1918440 +71196 4933432G23Rik MGI:MGI:1918446|Ensembl:ENSMUSG00000111843 +71198 Otud1 MGI:MGI:1918448|Ensembl:ENSMUSG00000043415|Vega:OTTMUSG00000011527 +71199 4933427I18Rik MGI:MGI:1918449 +71200 Dydc2 MGI:MGI:1918450|Ensembl:ENSMUSG00000021791 +71203 4933434M16Rik MGI:MGI:1918453 +71205 4933431M02Rik MGI:MGI:1918455 +71206 Katnal2 MGI:MGI:1924234|Ensembl:ENSMUSG00000025420|Vega:OTTMUSG00000033989 +71207 Nudt4 MGI:MGI:1918457|Ensembl:ENSMUSG00000020029 +71208 4933440M02Rik MGI:MGI:1918458|Ensembl:ENSMUSG00000045928 +71209 4933436E23Rik MGI:MGI:1918459|Ensembl:ENSMUSG00000103844 +71210 4933434C23Rik MGI:MGI:1918460 +71213 Cage1 MGI:MGI:1918463|Ensembl:ENSMUSG00000044566|Vega:OTTMUSG00000023064 +71215 4933436F18Rik MGI:MGI:1918465 +71216 4933427C19Rik MGI:MGI:1918466 +71217 4933431I19Rik MGI:MGI:1918467 +71218 4933428L01Rik MGI:MGI:1918468 +71220 4933427J07Rik MGI:MGI:1918470 +71223 Gpr15 MGI:MGI:1918473|Ensembl:ENSMUSG00000047293 +71226 4933433G19Rik MGI:MGI:1918476 +71227 Daw1 MGI:MGI:1923089|Ensembl:ENSMUSG00000053161|Vega:OTTMUSG00000022978 +71228 Dlg5 MGI:MGI:1918478|Ensembl:ENSMUSG00000021782|Vega:OTTMUSG00000036719 +71229 4933428P19Rik MGI:MGI:1918479 +71232 4933429K18Rik MGI:MGI:1918482 +71233 Enkur MGI:MGI:1918483|Ensembl:ENSMUSG00000026679|Vega:OTTMUSG00000011670 +71234 4933427E13Rik MGI:MGI:1918484|Ensembl:ENSMUSG00000033015 +71235 4933427I22Rik MGI:MGI:1918485|Ensembl:ENSMUSG00000085928 +71236 Rsph14 MGI:MGI:1918486|Ensembl:ENSMUSG00000009070|Vega:OTTMUSG00000032463 +71237 4933435G04Rik MGI:MGI:1918487 +71238 Sdhaf3 MGI:MGI:1913288|Ensembl:ENSMUSG00000042505|Vega:OTTMUSG00000024037 +71240 Osbpl7 MGI:MGI:1918490|Ensembl:ENSMUSG00000038534|Vega:OTTMUSG00000002232 +71241 Dmrtc2 MGI:MGI:1918491|Ensembl:ENSMUSG00000011349|Vega:OTTMUSG00000024043 +71242 Spata24 MGI:MGI:1918492|Ensembl:ENSMUSG00000024352 +71243 4933438A12Rik MGI:MGI:1918493 +71244 4933436H12Rik MGI:MGI:1918494|Ensembl:ENSMUSG00000108924 +71246 4933437I04Rik MGI:MGI:1918496 +71247 4933438B17Rik MGI:MGI:1918497|Ensembl:ENSMUSG00000105490 +71248 4933428M09Rik MGI:MGI:1918498|Ensembl:ENSMUSG00000042525|Vega:OTTMUSG00000018717 +71249 4933430N04Rik MGI:MGI:1918499|Ensembl:ENSMUSG00000108848 +71250 4933428C20Rik MGI:MGI:1918500 +71251 4933430L12Rik MGI:MGI:1918501 +71252 4933433N18Rik MGI:MGI:1918502 +71254 Naif1 MGI:MGI:1918504|Ensembl:ENSMUSG00000039164|Vega:OTTMUSG00000011985 +71259 4933433M23Rik MGI:MGI:1918509 +71263 Mro MGI:MGI:2152817|Ensembl:ENSMUSG00000064036|Vega:OTTMUSG00000028221 +71264 4933432I03Rik MGI:MGI:1918514 +71265 4933431G14Rik MGI:MGI:1918515|Ensembl:ENSMUSG00000108709 +71266 4933436P19Rik MGI:MGI:1918516 +71268 Lrrfip2 MGI:MGI:1918518|Ensembl:ENSMUSG00000032497|Vega:OTTMUSG00000052505 +71270 4933438K21Rik MGI:MGI:1918520|Ensembl:ENSMUSG00000093617 +71274 4933433G15Rik MGI:MGI:1918524|Ensembl:ENSMUSG00000097021 +71275 Noxred1 MGI:MGI:1918525|Ensembl:ENSMUSG00000072919 +71276 Ccdc57 MGI:MGI:1918526|Ensembl:ENSMUSG00000048445|Vega:OTTMUSG00000004162 +71277 4933435N07Rik MGI:MGI:1918527 +71278 4933430A20Rik MGI:MGI:1918528 +71279 Slc29a3 MGI:MGI:1918529|Ensembl:ENSMUSG00000020100|Vega:OTTMUSG00000030007 +71280 4933429H19Rik MGI:MGI:1918530 +71281 Apobec4 MGI:MGI:1918531|Ensembl:ENSMUSG00000055547|Vega:OTTMUSG00000019687 +71282 4933434P08Rik MGI:MGI:1918532 +71285 4933430H16Rik MGI:MGI:1918535|Ensembl:ENSMUSG00000109106 +71286 4933439J24Rik MGI:MGI:1918536 +71287 Cpvl MGI:MGI:1918537|Ensembl:ENSMUSG00000052955|Vega:OTTMUSG00000057154 +71288 4933440K10Rik MGI:MGI:1918538 +71289 4933436N17Rik MGI:MGI:1918539 +71290 4933436I20Rik MGI:MGI:1918540 +71291 4933435E02Rik MGI:MGI:1918541 +71293 4933428C19Rik MGI:MGI:1918543|Ensembl:ENSMUSG00000086355 +71294 Nr5a1os MGI:MGI:1918544 +71295 4933431K14Rik MGI:MGI:1918545 +71296 Crnde MGI:MGI:1918546|Ensembl:ENSMUSG00000031736 +71297 Platr20 MGI:MGI:1918547|Ensembl:ENSMUSG00000086646 +71298 4933431J24Rik MGI:MGI:1918548 +71299 4933439N06Rik MGI:MGI:1918549 +71300 Rnf148 MGI:MGI:1918550|Ensembl:ENSMUSG00000078179|Vega:OTTMUSG00000022891 +71301 4930593A02Rik MGI:MGI:1923132|Ensembl:ENSMUSG00000097725 +71302 Arhgap26 MGI:MGI:1918552|Ensembl:ENSMUSG00000036452|Vega:OTTMUSG00000020314 +71303 4933437G19Rik MGI:MGI:1918553 +71304 Wbscr25 MGI:MGI:1918554|Ensembl:ENSMUSG00000054909 +71306 Mfap3l MGI:MGI:1918556|Ensembl:ENSMUSG00000031647|Vega:OTTMUSG00000027221 +71307 1700018A04Rik MGI:MGI:1916631|Ensembl:ENSMUSG00000038408 +71308 4933430H06Rik MGI:MGI:1918558 +71309 4933435C09Rik MGI:MGI:1918559 +71310 Tbc1d9 MGI:MGI:1918560|Ensembl:ENSMUSG00000031709|Vega:OTTMUSG00000031541 +71311 4933428L12Rik MGI:MGI:1918561 +71313 Fsip1 MGI:MGI:1918563|Ensembl:ENSMUSG00000027344|Vega:OTTMUSG00000015226 +71314 4933433F19Rik MGI:MGI:1918564|Ensembl:ENSMUSG00000097044 +71316 4933430M04Rik MGI:MGI:1918566|Ensembl:ENSMUSG00000086892 +71319 4933439K11Rik MGI:MGI:1918569|Ensembl:ENSMUSG00000085184 +71320 4933435F18Rik MGI:MGI:1918570 +71321 4933440J02Rik MGI:MGI:1918571|Ensembl:ENSMUSG00000097082 +71322 4933431C10Rik MGI:MGI:1918572 +71323 Rassf8 MGI:MGI:1918573|Ensembl:ENSMUSG00000030259|Vega:OTTMUSG00000025464 +71325 Tchhl1 MGI:MGI:1918575|Ensembl:ENSMUSG00000027908|Vega:OTTMUSG00000051990 +71326 Treml1 MGI:MGI:1918576|Ensembl:ENSMUSG00000023993 +71327 5430402P08Rik MGI:MGI:1918577 +71330 Rcbtb1 MGI:MGI:1918580|Ensembl:ENSMUSG00000035469|Vega:OTTMUSG00000026152 +71331 5430411C19Rik MGI:MGI:1918581 +71333 5430408I23Rik MGI:MGI:1918583 +71334 5430416G10Rik MGI:MGI:1918584 +71335 5430430K15Rik MGI:MGI:1918585 +71336 Rbks MGI:MGI:1918586|Ensembl:ENSMUSG00000029136|Vega:OTTMUSG00000028317 +71337 5430402M21Rik MGI:MGI:1918587 +71338 Tprg MGI:MGI:1918588|Ensembl:ENSMUSG00000048399|Vega:OTTMUSG00000022676 +71339 5430400D12Rik MGI:MGI:1918589 +71340 Riok1 MGI:MGI:1918590|Ensembl:ENSMUSG00000021428 +71341 5430434N17Rik MGI:MGI:1918591 +71342 5430434I15Rik MGI:MGI:1918592|Ensembl:ENSMUSG00000106002 +71345 Ano9 MGI:MGI:1918595|Ensembl:ENSMUSG00000054662|Vega:OTTMUSG00000060387 +71348 5430439M09Rik MGI:MGI:1918598 +71349 5430427M07Rik MGI:MGI:1918599|Ensembl:ENSMUSG00000085004 +71351 5430402E10Rik MGI:MGI:1918601|Ensembl:ENSMUSG00000044121|Vega:OTTMUSG00000017873 +71353 5230401M06Rik MGI:MGI:1918603 +71354 Wdr31 MGI:MGI:1918604|Ensembl:ENSMUSG00000028391|Vega:OTTMUSG00000000235 +71355 Col24a1 MGI:MGI:1918605|Ensembl:ENSMUSG00000028197|Vega:OTTMUSG00000021259 +71357 5430435K18Rik MGI:MGI:1918607 +71361 Aifm2 MGI:MGI:1918611|Ensembl:ENSMUSG00000020085|Vega:OTTMUSG00000034135 +71362 5430440P10Rik MGI:MGI:1918612 +71363 Krtap7-1 MGI:MGI:1918613|Ensembl:ENSMUSG00000056706 +71365 Pdss2 MGI:MGI:1918615|Ensembl:ENSMUSG00000038240|Vega:OTTMUSG00000034999 +71367 Chst9 MGI:MGI:1918617|Ensembl:ENSMUSG00000047161|Vega:OTTMUSG00000028196 +71368 5430431A17Rik MGI:MGI:1918618|Ensembl:ENSMUSG00000108322 +71369 Krtap16-3 MGI:MGI:1918619|Ensembl:ENSMUSG00000096534|Vega:OTTMUSG00000044994 +71370 5430433H01Rik MGI:MGI:1918620 +71371 Arid5b MGI:MGI:2175912|Ensembl:ENSMUSG00000019947 +71373 Prr16 MGI:MGI:1918623|Ensembl:ENSMUSG00000073565 +71375 Foxn3 MGI:MGI:1918625|Ensembl:ENSMUSG00000033713|Vega:OTTMUSG00000042153 +71382 Pex1 MGI:MGI:1918632|Ensembl:ENSMUSG00000005907|Vega:OTTMUSG00000028545 +71384 5430440L12Rik MGI:MGI:1918634 +71385 5430434G16Rik MGI:MGI:1918635 +71386 Krtap28-13 MGI:MGI:1918636|Ensembl:ENSMUSG00000101315|Vega:OTTMUSG00000044999 +71388 5530401A14Rik MGI:MGI:1918638|Ensembl:ENSMUSG00000020703|Vega:OTTMUSG00000000857 +71389 Chd6 MGI:MGI:1918639|Ensembl:ENSMUSG00000057133|Vega:OTTMUSG00000001051 +71390 Slc6a19os MGI:MGI:1918640 +71392 5430401F13Rik MGI:MGI:1918642|Ensembl:ENSMUSG00000094113|Vega:OTTMUSG00000034586 +71393 Kctd6 MGI:MGI:1918643|Ensembl:ENSMUSG00000021752 +71395 5430419D17Rik MGI:MGI:1918645|Ensembl:ENSMUSG00000006204|Vega:OTTMUSG00000025413 +71398 5430427O19Rik MGI:MGI:1918648|Ensembl:ENSMUSG00000025058|Vega:OTTMUSG00000017917 +71405 Fam83c MGI:MGI:1918655|Ensembl:ENSMUSG00000074647|Vega:OTTMUSG00000015795 +71406 Spaar MGI:MGI:1918656|Ensembl:ENSMUSG00000028475|Vega:OTTMUSG00000007083 +71409 Fmnl2 MGI:MGI:1918659|Ensembl:ENSMUSG00000036053|Vega:OTTMUSG00000012431 +71410 5430425E15Rik MGI:MGI:1918660 +71412 Dhrs2 MGI:MGI:1918662|Ensembl:ENSMUSG00000022209|Vega:OTTMUSG00000027926 +71413 5430410E06Rik MGI:MGI:1918663 +71414 5430427G11Rik MGI:MGI:1918664 +71416 5430425K12Rik MGI:MGI:1918666 +71420 5530400N10Rik MGI:MGI:1918670 +71421 Amtn MGI:MGI:1918671|Ensembl:ENSMUSG00000029282|Vega:OTTMUSG00000055384 +71422 5430428K19Rik MGI:MGI:1918672 +71424 5430430B14Rik MGI:MGI:1918674 +71425 Bpifb9a MGI:MGI:3767993|Ensembl:ENSMUSG00000067998|Vega:OTTMUSG00000015885 +71430 5430416B10Rik MGI:MGI:1918680 +71432 5430437J10Rik MGI:MGI:1918682 +71435 Arhgap21 MGI:MGI:1918685|Ensembl:ENSMUSG00000036591|Vega:OTTMUSG00000011591 +71436 Flrt3 MGI:MGI:1918686|Ensembl:ENSMUSG00000051379|Vega:OTTMUSG00000015600 +71443 5530402H23Rik MGI:MGI:1918693 +71445 5530601H04Rik MGI:MGI:1918695|Ensembl:ENSMUSG00000087174 +71446 Wrb MGI:MGI:2136882|Ensembl:ENSMUSG00000023147|Vega:OTTMUSG00000020058 +71447 5530402G07Rik MGI:MGI:1918697 +71448 Tmem80 MGI:MGI:1918698|Ensembl:ENSMUSG00000025505|Vega:OTTMUSG00000032934 +71449 Mettl13 MGI:MGI:1918699|Ensembl:ENSMUSG00000026694|Vega:OTTMUSG00000022659 +71452 Ankrd40 MGI:MGI:1918702|Ensembl:ENSMUSG00000020864|Vega:OTTMUSG00000001717 +71453 Krtap2-4 MGI:MGI:1918703|Ensembl:ENSMUSG00000060756|Vega:OTTMUSG00000002194 +71454 6620401J10Rik MGI:MGI:1918704 +71456 8430401P03Rik MGI:MGI:1918706 +71457 7420701I03Rik MGI:MGI:1918707|Ensembl:ENSMUSG00000113620 +71458 Bcor MGI:MGI:1918708|Ensembl:ENSMUSG00000040363|Vega:OTTMUSG00000016940 +71461 Ptk7 MGI:MGI:1918711|Ensembl:ENSMUSG00000023972 +71465 8430413B15Rik MGI:MGI:1918715 +71466 8430415D16Rik MGI:MGI:1918716 +71468 Obox1 MGI:MGI:1918718|Ensembl:ENSMUSG00000054310|Vega:OTTMUSG00000037391 +71469 8430416G17Rik MGI:MGI:1918719 +71471 8430422J01Rik MGI:MGI:1918721 +71472 Usp19 MGI:MGI:1918722|Ensembl:ENSMUSG00000006676|Vega:OTTMUSG00000050758 +71473 8430423G03Rik MGI:MGI:1918723|Ensembl:ENSMUSG00000079069 +71474 Ppp6r2 MGI:MGI:1918724|Ensembl:ENSMUSG00000036561 +71475 8430413D17Rik MGI:MGI:1918725 +71481 Alpk1 MGI:MGI:1918731|Ensembl:ENSMUSG00000028028|Vega:OTTMUSG00000031352 +71484 8430415O14Rik MGI:MGI:1918734 +71489 Bcas3os1 MGI:MGI:1918739|Ensembl:ENSMUSG00000086199 +71491 8430418B16Rik MGI:MGI:1918741 +71492 Bbs7 MGI:MGI:1918742|Ensembl:ENSMUSG00000037325|Vega:OTTMUSG00000006487 +71494 8430406P12Rik MGI:MGI:1918744 +71501 8430425A16Rik MGI:MGI:1918751 +71507 8430437B07Rik MGI:MGI:1918757 +71508 Zfp935 MGI:MGI:1918758|Ensembl:ENSMUSG00000113450 +71510 8430436N08Rik MGI:MGI:1918760|Ensembl:ENSMUSG00000086070 +71511 9030601B04Rik MGI:MGI:1918761 +71512 9030419F21Rik MGI:MGI:1918762 +71513 9030607L20Rik MGI:MGI:1918763 +71514 Sfpq MGI:MGI:1918764|Ensembl:ENSMUSG00000028820|Vega:OTTMUSG00000009316 +71517 9030624J02Rik MGI:MGI:1918767|Ensembl:ENSMUSG00000030982|Vega:OTTMUSG00000025727 +71519 Cyp2u1 MGI:MGI:1918769|Ensembl:ENSMUSG00000027983|Vega:OTTMUSG00000054796 +71520 Grap MGI:MGI:1918770|Ensembl:ENSMUSG00000004837|Vega:OTTMUSG00000005843 +71521 Pds5a MGI:MGI:1918771|Ensembl:ENSMUSG00000029202|Vega:OTTMUSG00000055174 +71522 Ggt6 MGI:MGI:1918772|Ensembl:ENSMUSG00000040471|Vega:OTTMUSG00000006109 +71523 8430429K09Rik MGI:MGI:1918773|Ensembl:ENSMUSG00000034587 +71524 8430432A02Rik MGI:MGI:1918774 +71526 9030607J07Rik MGI:MGI:1918776 +71528 9030404E10Rik MGI:MGI:1918778 +71529 Kazn MGI:MGI:1918779|Ensembl:ENSMUSG00000040606|Vega:OTTMUSG00000010182 +71532 Fam217b MGI:MGI:1918782|Ensembl:ENSMUSG00000070476|Vega:OTTMUSG00000016354 +71533 9030407C09Rik MGI:MGI:1918783 +71534 9030408N04Rik MGI:MGI:1918784 +71535 9030411M13Rik MGI:MGI:1918785 +71536 8430437O03Rik MGI:MGI:1918786 +71538 Fbxo9 MGI:MGI:1918788|Ensembl:ENSMUSG00000001366|Vega:OTTMUSG00000034577 +71542 8430439C15Rik MGI:MGI:1918792 +71544 Arhgap42 MGI:MGI:1918794|Ensembl:ENSMUSG00000050730|Vega:OTTMUSG00000043543 +71545 9030625G05Rik MGI:MGI:1918795 +71554 8430427G23Rik MGI:MGI:1918804 +71556 8430434A19Rik MGI:MGI:1918806 +71561 8430437N05Rik MGI:MGI:1918811 +71562 Afmid MGI:MGI:2448704|Ensembl:ENSMUSG00000017718|Vega:OTTMUSG00000042165 +71564 Izumo4 MGI:MGI:1918814|Ensembl:ENSMUSG00000055862 +71565 9030418E23Rik MGI:MGI:1918815 +71566 Clmp MGI:MGI:1918816|Ensembl:ENSMUSG00000032024|Vega:OTTMUSG00000030244 +71567 Mcm9 MGI:MGI:1918817|Ensembl:ENSMUSG00000058298 +71569 9030613N10Rik MGI:MGI:1918819 +71573 9130025I19Rik MGI:MGI:1918823 +71575 9130001E16Rik MGI:MGI:1918825 +71576 9130409J20Rik MGI:MGI:1918826|Ensembl:ENSMUSG00000085683 +71578 Sval1 MGI:MGI:1918828|Ensembl:ENSMUSG00000029865|Vega:OTTMUSG00000026917 +71581 9130015A21Rik MGI:MGI:1918831|Ensembl:ENSMUSG00000113985 +71583 9130008F23Rik MGI:MGI:1918833|Ensembl:ENSMUSG00000054951 +71584 Gdpd2 MGI:MGI:1918834|Ensembl:ENSMUSG00000019359|Vega:OTTMUSG00000018299 +71585 9130403I23Rik MGI:MGI:1918835 +71586 Ifih1 MGI:MGI:1918836|Ensembl:ENSMUSG00000026896|Vega:OTTMUSG00000012871 +71588 9130009M17Rik MGI:MGI:1918838 +71591 Zfp251 MGI:MGI:1918841|Ensembl:ENSMUSG00000022526 +71592 Pogk MGI:MGI:1918842|Ensembl:ENSMUSG00000040596|Vega:OTTMUSG00000026882 +71594 9130009I01Rik MGI:MGI:1918844 +71597 Isx MGI:MGI:1918847|Ensembl:ENSMUSG00000031621|Vega:OTTMUSG00000037604 +71599 Senp8 MGI:MGI:1918849|Ensembl:ENSMUSG00000051705|Vega:OTTMUSG00000063327 +71601 Ceacam20 MGI:MGI:1918851|Ensembl:ENSMUSG00000070777|Vega:OTTMUSG00000059297 +71602 Myo1e MGI:MGI:106621|Ensembl:ENSMUSG00000032220|Vega:OTTMUSG00000063621 +71603 9130004J05Rik MGI:MGI:1918853 +71604 9130413E14Rik MGI:MGI:1918854 +71607 Snx20 MGI:MGI:1918857|Ensembl:ENSMUSG00000031662|Vega:OTTMUSG00000061527 +71609 Tradd MGI:MGI:109200|Ensembl:ENSMUSG00000031887|Vega:OTTMUSG00000027472 +71611 9130022K11Rik MGI:MGI:1918861 +71612 9130410C08Rik MGI:MGI:1918862 +71613 9130015L21Rik MGI:MGI:1918863|Ensembl:ENSMUSG00000086653 +71617 9130011E15Rik MGI:MGI:1918867|Ensembl:ENSMUSG00000039901 +71619 Arl14 MGI:MGI:1918869|Ensembl:ENSMUSG00000098207|Vega:OTTMUSG00000043556 +71620 9130016M20Rik MGI:MGI:1918870 +71621 4833404L02Rik MGI:MGI:1918871 +71623 Krtap5-2 MGI:MGI:1918873|Ensembl:ENSMUSG00000054759|Vega:OTTMUSG00000045003 +71624 4833411C07Rik MGI:MGI:1918874|Ensembl:ENSMUSG00000109089 +71633 4833414E09Rik MGI:MGI:1918883 +71637 4930413F20Rik MGI:MGI:1918887 +71638 4930431F10Rik MGI:MGI:1918888|Ensembl:ENSMUSG00000111494 +71639 4930430E12Rik MGI:MGI:1918889 +71640 Zfp949 MGI:MGI:1918890|Ensembl:ENSMUSG00000032425|Vega:OTTMUSG00000034721 +71641 4930415K08Rik MGI:MGI:1918891 +71642 4930413E20Rik MGI:MGI:1918892 +71643 Zgrf1 MGI:MGI:1918893|Ensembl:ENSMUSG00000051278|Vega:OTTMUSG00000053270 +71647 4930447N08Rik MGI:MGI:1918897|Ensembl:ENSMUSG00000106583 +71648 Optn MGI:MGI:1918898|Ensembl:ENSMUSG00000026672|Vega:OTTMUSG00000010864 +71650 4930456L15Rik MGI:MGI:1918900|Ensembl:ENSMUSG00000078618 +71653 Shtn1 MGI:MGI:1918903|Ensembl:ENSMUSG00000041362 +71654 4930518P08Rik MGI:MGI:1918904|Ensembl:ENSMUSG00000113652 +71655 4930518F22Rik MGI:MGI:1918905 +71656 4930513L20Rik MGI:MGI:1918906 +71657 Srrm3os MGI:MGI:1918907 +71660 Rarres2 MGI:MGI:1918910|Ensembl:ENSMUSG00000009281|Vega:OTTMUSG00000057233 +71661 0610005C13Rik MGI:MGI:1918911|Ensembl:ENSMUSG00000109644 +71664 Mettl7b MGI:MGI:1918914|Ensembl:ENSMUSG00000025347 +71665 Fuca1 MGI:MGI:95593|Ensembl:ENSMUSG00000028673|Vega:OTTMUSG00000009850 +71667 Tmem248 MGI:MGI:1918917|Ensembl:ENSMUSG00000053094|Vega:OTTMUSG00000055826 +71670 Acy3 MGI:MGI:1918920|Ensembl:ENSMUSG00000024866 +71671 0610009F21Rik MGI:MGI:1918921 +71673 Rnf215 MGI:MGI:1918923|Ensembl:ENSMUSG00000003581|Vega:OTTMUSG00000005052 +71675 0610010F05Rik MGI:MGI:1918925|Ensembl:ENSMUSG00000042208|Vega:OTTMUSG00000005276 +71676 0610012D04Rik MGI:MGI:1918926 +71678 Brox MGI:MGI:1918928|Ensembl:ENSMUSG00000046836|Vega:OTTMUSG00000050558 +71679 Atp5h MGI:MGI:1918929|Ensembl:ENSMUSG00000034566|Vega:OTTMUSG00000003445 +71681 0610009K14Rik MGI:MGI:1918931 +71682 Wdr27 MGI:MGI:1918932|Ensembl:ENSMUSG00000046991 +71683 Gypc MGI:MGI:1098566|Ensembl:ENSMUSG00000090523|Vega:OTTMUSG00000037029 +71684 Rbm43 MGI:MGI:1918934|Ensembl:ENSMUSG00000036249|Vega:OTTMUSG00000012408 +71685 Galnt14 MGI:MGI:1918935|Ensembl:ENSMUSG00000024064|Vega:OTTMUSG00000026110 +71687 Tmem25 MGI:MGI:1918937|Ensembl:ENSMUSG00000002032|Vega:OTTMUSG00000016729 +71688 0610042B02Rik MGI:MGI:1918938 +71690 Esm1 MGI:MGI:1918940|Ensembl:ENSMUSG00000042379|Vega:OTTMUSG00000027691 +71691 Pnmal1 MGI:MGI:1918941|Ensembl:ENSMUSG00000041141|Vega:OTTMUSG00000058183 +71692 0710005I21Rik MGI:MGI:1918942 +71693 Colec11 MGI:MGI:1918943|Ensembl:ENSMUSG00000036655 +71695 0910001E24Rik MGI:MGI:1918945 +71697 0710008F09Rik MGI:MGI:1918947 +71699 Slc41a3 MGI:MGI:1918949|Ensembl:ENSMUSG00000030089|Vega:OTTMUSG00000024324 +71701 Pnpt1 MGI:MGI:1918951|Ensembl:ENSMUSG00000020464|Vega:OTTMUSG00000005318 +71702 Cdc5l MGI:MGI:1918952|Ensembl:ENSMUSG00000023932 +71703 Armcx3 MGI:MGI:1918953|Ensembl:ENSMUSG00000049047|Vega:OTTMUSG00000019455 +71704 Arhgef3 MGI:MGI:1918954|Ensembl:ENSMUSG00000021895 +71706 Slc46a3 MGI:MGI:1918956|Ensembl:ENSMUSG00000029650|Vega:OTTMUSG00000028765 +71707 Ubiad1 MGI:MGI:1918957|Ensembl:ENSMUSG00000047719|Vega:OTTMUSG00000010930 +71709 Syde1 MGI:MGI:1918959|Ensembl:ENSMUSG00000032714 +71710 Lrrcc1 MGI:MGI:1918960|Ensembl:ENSMUSG00000027550|Vega:OTTMUSG00000035907 +71711 Mus81 MGI:MGI:1918961|Ensembl:ENSMUSG00000024906|Vega:OTTMUSG00000033940 +71712 Dram1 MGI:MGI:1918962|Ensembl:ENSMUSG00000020057|Vega:OTTMUSG00000023972 +71713 Cdc40 MGI:MGI:1918963|Ensembl:ENSMUSG00000038446|Vega:OTTMUSG00000063435 +71715 Dhx35 MGI:MGI:1918965|Ensembl:ENSMUSG00000027655|Vega:OTTMUSG00000015943 +71718 Telo2 MGI:MGI:1918968|Ensembl:ENSMUSG00000024170|Vega:OTTMUSG00000030783 +71719 1200003I10Rik MGI:MGI:1918969 +71720 Osbpl3 MGI:MGI:1918970|Ensembl:ENSMUSG00000029822|Vega:OTTMUSG00000022235 +71721 Fam13c MGI:MGI:1918971|Ensembl:ENSMUSG00000043259|Vega:OTTMUSG00000037023 +71722 Cic MGI:MGI:1918972|Ensembl:ENSMUSG00000005442|Vega:OTTMUSG00000036029 +71723 Dhx34 MGI:MGI:1918973|Ensembl:ENSMUSG00000006019|Vega:OTTMUSG00000029681 +71724 Aox3 MGI:MGI:1918974|Ensembl:ENSMUSG00000064294|Vega:OTTMUSG00000021877 +71726 Smug1 MGI:MGI:1918976|Ensembl:ENSMUSG00000036061 +71728 Stk11ip MGI:MGI:1918978|Ensembl:ENSMUSG00000026213|Vega:OTTMUSG00000019423 +71729 Rgs12 MGI:MGI:1918979|Ensembl:ENSMUSG00000029101|Vega:OTTMUSG00000023191 +71732 Vps11 MGI:MGI:1918982|Ensembl:ENSMUSG00000032127|Vega:OTTMUSG00000063261 +71733 Susd2 MGI:MGI:1918983|Ensembl:ENSMUSG00000006342 +71735 Lrwd1 MGI:MGI:1918985|Ensembl:ENSMUSG00000029703|Vega:OTTMUSG00000025432 +71738 Mamdc2 MGI:MGI:1918988|Ensembl:ENSMUSG00000033207 +71739 1200015M12Rik MGI:MGI:1918989 +71740 Nectin4 MGI:MGI:1918990|Ensembl:ENSMUSG00000006411|Vega:OTTMUSG00000021602 +71742 Ulk3 MGI:MGI:1918992|Ensembl:ENSMUSG00000032308|Vega:OTTMUSG00000063191 +71743 Coasy MGI:MGI:1918993|Ensembl:ENSMUSG00000001755|Vega:OTTMUSG00000002690 +71745 Cul2 MGI:MGI:1918995|Ensembl:ENSMUSG00000024231|Vega:OTTMUSG00000034308 +71746 Rgl3 MGI:MGI:1918996|Ensembl:ENSMUSG00000040146|Vega:OTTMUSG00000062324 +71750 R3hdm2 MGI:MGI:1919000|Ensembl:ENSMUSG00000025404|Vega:OTTMUSG00000035856 +71751 Map3k13 MGI:MGI:2444243|Ensembl:ENSMUSG00000033618 +71752 Gtf3c2 MGI:MGI:1919002|Ensembl:ENSMUSG00000101678|Ensembl:ENSMUSG00000106864|Vega:OTTMUSG00000022465|Vega:OTTMUSG00000046332 +71753 Tmprss6 MGI:MGI:1919003|Ensembl:ENSMUSG00000016942 +71754 Cyp2d40 MGI:MGI:1919004|Ensembl:ENSMUSG00000068083 +71755 Dhdh MGI:MGI:1919005|Ensembl:ENSMUSG00000011382|Vega:OTTMUSG00000024072 +71756 Cpn2 MGI:MGI:1919006|Ensembl:ENSMUSG00000023176 +71760 Etnppl MGI:MGI:1919010|Ensembl:ENSMUSG00000019232|Vega:OTTMUSG00000035930 +71761 Amdhd1 MGI:MGI:1919011|Ensembl:ENSMUSG00000015890|Vega:OTTMUSG00000030967 +71764 C2cd2l MGI:MGI:1919014|Ensembl:ENSMUSG00000032120|Vega:OTTMUSG00000063241 +71765 Klhdc3 MGI:MGI:2651568|Ensembl:ENSMUSG00000063576 +71766 Raver1 MGI:MGI:1919016|Ensembl:ENSMUSG00000010205|Ensembl:ENSMUSG00000111497|Vega:OTTMUSG00000063215|Vega:OTTMUSG00000063229 +71767 Tysnd1 MGI:MGI:1919017|Ensembl:ENSMUSG00000020087 +71768 Vwce MGI:MGI:1919018|Ensembl:ENSMUSG00000043789 +71769 Bbs10 MGI:MGI:1919019|Ensembl:ENSMUSG00000035759 +71770 Ap2b1 MGI:MGI:1919020|Ensembl:ENSMUSG00000035152|Vega:OTTMUSG00000000915 +71772 Plbd2 MGI:MGI:1919022|Ensembl:ENSMUSG00000029598|Vega:OTTMUSG00000025296 +71773 Ugt2b1 MGI:MGI:1919023|Ensembl:ENSMUSG00000035836|Vega:OTTMUSG00000026776 +71774 Shroom1 MGI:MGI:1919024|Ensembl:ENSMUSG00000018387|Vega:OTTMUSG00000005639 +71775 1300017J02Rik MGI:MGI:1919025|Ensembl:ENSMUSG00000033688|Vega:OTTMUSG00000033542 +71776 Tha1 MGI:MGI:1919026|Ensembl:ENSMUSG00000017713|Vega:OTTMUSG00000003730 +71777 Ing3 MGI:MGI:1919027|Ensembl:ENSMUSG00000029670|Vega:OTTMUSG00000017304 +71778 Klhl5 MGI:MGI:1919028|Ensembl:ENSMUSG00000054920|Vega:OTTMUSG00000022023 +71779 March8 MGI:MGI:1919029|Ensembl:ENSMUSG00000025702|Vega:OTTMUSG00000016676 +71780 Isyna1 MGI:MGI:1919030|Ensembl:ENSMUSG00000019139|Vega:OTTMUSG00000061446 +71781 Slc16a14 MGI:MGI:1919031|Ensembl:ENSMUSG00000026220|Vega:OTTMUSG00000048008 +71782 Ankle2 MGI:MGI:1261856|Ensembl:ENSMUSG00000029501|Vega:OTTMUSG00000054096 +71783 Maskbp3 MGI:MGI:3845902 +71785 Pdgfd MGI:MGI:1919035|Ensembl:ENSMUSG00000032006|Vega:OTTMUSG00000062234 +71787 Trnau1ap MGI:MGI:1919037|Ensembl:ENSMUSG00000028898|Vega:OTTMUSG00000009574 +71790 Anxa9 MGI:MGI:1923711|Ensembl:ENSMUSG00000015702|Vega:OTTMUSG00000022052 +71791 Cpa4 MGI:MGI:1919041|Ensembl:ENSMUSG00000039070|Vega:OTTMUSG00000014388 +71793 Ints12 MGI:MGI:1919043|Ensembl:ENSMUSG00000028016|Vega:OTTMUSG00000017460 +71795 Pitpnc1 MGI:MGI:1919045|Ensembl:ENSMUSG00000040430|Vega:OTTMUSG00000003636 +71797 Chst13 MGI:MGI:1919047|Ensembl:ENSMUSG00000056643|Vega:OTTMUSG00000057742 +71799 Ptcd1 MGI:MGI:1919049|Ensembl:ENSMUSG00000029624|Vega:OTTMUSG00000023010 +71801 Plekhf2 MGI:MGI:1919051|Ensembl:ENSMUSG00000049969|Vega:OTTMUSG00000004511 +71802 1500010C09Rik MGI:MGI:1919052 +71803 Slc25a18 MGI:MGI:1919053|Ensembl:ENSMUSG00000004902|Vega:OTTMUSG00000056827 +71804 Mtfr2 MGI:MGI:1919054|Ensembl:ENSMUSG00000019992|Vega:OTTMUSG00000063831 +71805 Nup93 MGI:MGI:1919055|Ensembl:ENSMUSG00000032939|Vega:OTTMUSG00000061621 +71807 Tars2 MGI:MGI:1919057|Ensembl:ENSMUSG00000028107|Vega:OTTMUSG00000053011 +71810 Ranbp3 MGI:MGI:1919060|Ensembl:ENSMUSG00000002372 +71811 2610027H17Rik MGI:MGI:1919061 +71813 2610028J07Rik MGI:MGI:1919063 +71815 2810414N06Rik MGI:MGI:1919065 +71816 Rnf180 MGI:MGI:1919066|Ensembl:ENSMUSG00000021720 +71817 Tmem50a MGI:MGI:1919067|Ensembl:ENSMUSG00000028822|Vega:OTTMUSG00000011093 +71818 3200001D21Rik MGI:MGI:1919068|Ensembl:ENSMUSG00000113434 +71819 Kif23 MGI:MGI:1919069|Ensembl:ENSMUSG00000032254|Vega:OTTMUSG00000062532 +71820 Wdr34 MGI:MGI:1919070|Ensembl:ENSMUSG00000039715|Vega:OTTMUSG00000016727 +71824 1700006A11Rik MGI:MGI:1919074|Ensembl:ENSMUSG00000027973|Vega:OTTMUSG00000052587 +71826 1700001F09Rik MGI:MGI:1919076|Ensembl:ENSMUSG00000095384|Vega:OTTMUSG00000036374 +71827 Lrrc34 MGI:MGI:1919077|Ensembl:ENSMUSG00000027702|Vega:OTTMUSG00000022332 +71828 Gtf2a1l MGI:MGI:1919078|Ensembl:ENSMUSG00000024154|Vega:OTTMUSG00000028528 +71829 Ddi1 MGI:MGI:1919079|Ensembl:ENSMUSG00000047619|Vega:OTTMUSG00000062235 +71830 Pdilt MGI:MGI:1919080|Ensembl:ENSMUSG00000030968|Vega:OTTMUSG00000043386 +71831 Iqcm MGI:MGI:1919081|Ensembl:ENSMUSG00000031620|Vega:OTTMUSG00000031095 +71832 Csl MGI:MGI:1919082|Ensembl:ENSMUSG00000046934 +71833 Dcaf7 MGI:MGI:1919083|Ensembl:ENSMUSG00000049354|Vega:OTTMUSG00000003052 +71834 Zbtb43 MGI:MGI:1919084|Ensembl:ENSMUSG00000026788|Vega:OTTMUSG00000012588 +71835 Lancl2 MGI:MGI:1919085|Ensembl:ENSMUSG00000062190|Vega:OTTMUSG00000023246 +71836 Shcbp1l MGI:MGI:1919086|Ensembl:ENSMUSG00000042708|Vega:OTTMUSG00000022957 +71837 1700003E16Rik MGI:MGI:1919087|Ensembl:ENSMUSG00000030030|Vega:OTTMUSG00000057902 +71838 Phf7 MGI:MGI:1919088|Ensembl:ENSMUSG00000021902 +71839 Osgin1 MGI:MGI:1919089|Ensembl:ENSMUSG00000074063|Vega:OTTMUSG00000027525 +71840 Tekt4 MGI:MGI:1919090|Ensembl:ENSMUSG00000024175|Vega:OTTMUSG00000035768 +71841 Tcp11x2 MGI:MGI:1919091|Ensembl:ENSMUSG00000058252|Vega:OTTMUSG00000018757 +71843 R3hcc1 MGI:MGI:1919093|Ensembl:ENSMUSG00000034194|Vega:OTTMUSG00000029904 +71844 Nupl1 MGI:MGI:1919094|Ensembl:ENSMUSG00000063895 +71846 Syce2 MGI:MGI:1919096|Ensembl:ENSMUSG00000003824|Vega:OTTMUSG00000022282 +71847 Btbd35f1 MGI:MGI:1919097|Ensembl:ENSMUSG00000094309 +71848 1700024J04Rik MGI:MGI:1919098 +71853 Pdia6 MGI:MGI:1919103|Ensembl:ENSMUSG00000020571|Vega:OTTMUSG00000023877 +71854 Dpep3 MGI:MGI:1919104|Ensembl:ENSMUSG00000031898|Vega:OTTMUSG00000061940 +71855 1700015O11Rik MGI:MGI:1919105 +71856 Wfdc3 MGI:MGI:1923897|Ensembl:ENSMUSG00000076434|Vega:OTTMUSG00000001099 +71860 Cfap52 MGI:MGI:1919110|Ensembl:ENSMUSG00000020904|Vega:OTTMUSG00000005936 +71861 Zswim2 MGI:MGI:1919111|Ensembl:ENSMUSG00000034552|Vega:OTTMUSG00000013389 +71862 Gpr160 MGI:MGI:1919112|Ensembl:ENSMUSG00000037661|Vega:OTTMUSG00000022043 +71863 Tex44 MGI:MGI:1919113|Ensembl:ENSMUSG00000036574|Vega:OTTMUSG00000042357 +71864 Fam217a MGI:MGI:1919114|Ensembl:ENSMUSG00000021414 +71865 Fbxo30 MGI:MGI:1919115|Ensembl:ENSMUSG00000047648|Vega:OTTMUSG00000032736 +71867 1700016G22Rik MGI:MGI:1919117|Ensembl:ENSMUSG00000100625 +71868 Thegl MGI:MGI:1919118|Ensembl:ENSMUSG00000029248|Vega:OTTMUSG00000026770 +71869 Serpinb12 MGI:MGI:1919119|Ensembl:ENSMUSG00000059956|Vega:OTTMUSG00000021002 +71870 Cfap45 MGI:MGI:1919120|Ensembl:ENSMUSG00000026546|Vega:OTTMUSG00000034521 +71872 Aox4 MGI:MGI:1919122|Ensembl:ENSMUSG00000038242|Vega:OTTMUSG00000026036 +71873 2310003N18Rik MGI:MGI:1919123|Ensembl:ENSMUSG00000110916 +71874 2310007B03Rik MGI:MGI:1919124|Ensembl:ENSMUSG00000034159|Vega:OTTMUSG00000026755 +71875 2300010F08Rik MGI:MGI:1919125 +71876 Cenpu MGI:MGI:1919126|Ensembl:ENSMUSG00000031629|Vega:OTTMUSG00000031616 +71877 Efhc1 MGI:MGI:1919127|Ensembl:ENSMUSG00000041809|Vega:OTTMUSG00000029838 +71878 Fam83d MGI:MGI:1919128|Ensembl:ENSMUSG00000027654|Vega:OTTMUSG00000015941 +71881 Apmap MGI:MGI:1919131|Ensembl:ENSMUSG00000033096|Vega:OTTMUSG00000015735 +71883 Coq2 MGI:MGI:1919133|Ensembl:ENSMUSG00000029319|Vega:OTTMUSG00000026156 +71884 Chit1 MGI:MGI:1919134|Ensembl:ENSMUSG00000026450|Vega:OTTMUSG00000021755 +71885 Faap100 MGI:MGI:1919135|Ensembl:ENSMUSG00000025384|Vega:OTTMUSG00000004171 +71886 2310002L09Rik MGI:MGI:1916780|Ensembl:ENSMUSG00000028396|Vega:OTTMUSG00000004011 +71887 Ppm1j MGI:MGI:1919137|Ensembl:ENSMUSG00000002228|Vega:OTTMUSG00000029325 +71888 Krt33a MGI:MGI:1919138|Ensembl:ENSMUSG00000035592|Vega:OTTMUSG00000002183 +71889 Epn3 MGI:MGI:1919139|Ensembl:ENSMUSG00000010080|Vega:OTTMUSG00000001998 +71890 Mad2l2 MGI:MGI:1919140|Ensembl:ENSMUSG00000029003|Vega:OTTMUSG00000010954 +71891 Cdadc1 MGI:MGI:1919141|Ensembl:ENSMUSG00000021982 +71893 Noxo1 MGI:MGI:1919143|Ensembl:ENSMUSG00000019320|Vega:OTTMUSG00000021039 +71897 Lypd6b MGI:MGI:1919147|Ensembl:ENSMUSG00000026765|Vega:OTTMUSG00000012367 +71898 Apol9b MGI:MGI:1919148|Ensembl:ENSMUSG00000068246 +71900 Tmem106b MGI:MGI:1919150|Ensembl:ENSMUSG00000029571|Vega:OTTMUSG00000024096 +71901 Fam219a MGI:MGI:1919151|Ensembl:ENSMUSG00000028439|Vega:OTTMUSG00000006658 +71902 Cand1 MGI:MGI:1261820|Ensembl:ENSMUSG00000020114|Vega:OTTMUSG00000030921 +71903 Ces2f MGI:MGI:1919153|Ensembl:ENSMUSG00000062826|Vega:OTTMUSG00000061988 +71904 Paqr7 MGI:MGI:1919154|Ensembl:ENSMUSG00000037348|Vega:OTTMUSG00000011084 +71907 Serpina9 MGI:MGI:1919157|Ensembl:ENSMUSG00000058260|Vega:OTTMUSG00000035417 +71908 Cldn23 MGI:MGI:1919158|Ensembl:ENSMUSG00000055976|Vega:OTTMUSG00000061042 +71909 Haus5 MGI:MGI:1919159|Ensembl:ENSMUSG00000078762|Vega:OTTMUSG00000026178 +71910 Plpp5 MGI:MGI:1919160|Ensembl:ENSMUSG00000031570|Vega:OTTMUSG00000033438 +71911 Bdh1 MGI:MGI:1919161|Ensembl:ENSMUSG00000046598|Vega:OTTMUSG00000026185 +71912 Jsrp1 MGI:MGI:1916700|Ensembl:ENSMUSG00000020216|Vega:OTTMUSG00000042544 +71913 Tmem79 MGI:MGI:1919163|Ensembl:ENSMUSG00000001420|Vega:OTTMUSG00000022067 +71914 Antxr2 MGI:MGI:1919164|Ensembl:ENSMUSG00000029338|Vega:OTTMUSG00000053314 +71915 2310058F05Rik MGI:MGI:1919165 +71916 Dus4l MGI:MGI:1919166|Ensembl:ENSMUSG00000020648 +71918 Zcchc24 MGI:MGI:1919168|Ensembl:ENSMUSG00000055538|Vega:OTTMUSG00000044564 +71919 Rpap3 MGI:MGI:1277218|Ensembl:ENSMUSG00000022466 +71920 Epgn MGI:MGI:1919170|Ensembl:ENSMUSG00000035020|Vega:OTTMUSG00000026774 +71921 2310058N22Rik MGI:MGI:1919171 +71923 Borcs6 MGI:MGI:1919173|Ensembl:ENSMUSG00000045176|Vega:OTTMUSG00000005958 +71924 Tube1 MGI:MGI:1919174|Ensembl:ENSMUSG00000019845|Vega:OTTMUSG00000063414 +71927 Itfg1 MGI:MGI:106419|Ensembl:ENSMUSG00000031703|Vega:OTTMUSG00000061424 +71928 2310047K21Rik MGI:MGI:1919178 +71929 Tmem123 MGI:MGI:1919179|Ensembl:ENSMUSG00000050912|Vega:OTTMUSG00000034120 +71930 2310043M15Rik MGI:MGI:1919180 +71931 Ift88os MGI:MGI:1919181 +71932 Ephx3 MGI:MGI:1919182|Ensembl:ENSMUSG00000037577|Vega:OTTMUSG00000034768 +71934 Car13 MGI:MGI:1931322|Ensembl:ENSMUSG00000027555|Vega:OTTMUSG00000026447 +71939 Apol6 MGI:MGI:1919189|Ensembl:ENSMUSG00000033576|Vega:OTTMUSG00000032804 +71941 Cars2 MGI:MGI:1919191|Ensembl:ENSMUSG00000056228|Vega:OTTMUSG00000060753 +71943 Tom1l1 MGI:MGI:1919193|Ensembl:ENSMUSG00000020541|Vega:OTTMUSG00000001600 +71946 Endod1 MGI:MGI:1919196|Ensembl:ENSMUSG00000037419|Vega:OTTMUSG00000062539 +71947 Tmem94 MGI:MGI:1919197|Ensembl:ENSMUSG00000020747|Vega:OTTMUSG00000003538 +71949 Cers5 MGI:MGI:1919199|Ensembl:ENSMUSG00000023021|Vega:OTTMUSG00000042003 +71950 Nanog MGI:MGI:1919200|Ensembl:ENSMUSG00000012396|Vega:OTTMUSG00000023511 +71951 Gpc2 MGI:MGI:1919201|Ensembl:ENSMUSG00000029510|Vega:OTTMUSG00000022763 +71952 Riox1 MGI:MGI:1919202|Ensembl:ENSMUSG00000046791 +71954 Suds3 MGI:MGI:1919204|Ensembl:ENSMUSG00000066900|Vega:OTTMUSG00000056114 +71955 Ist1 MGI:MGI:1919205|Ensembl:ENSMUSG00000031729|Vega:OTTMUSG00000061920 +71956 Rnf135 MGI:MGI:1919206|Ensembl:ENSMUSG00000020707|Vega:OTTMUSG00000000220 +71957 Ints11 MGI:MGI:1919207|Ensembl:ENSMUSG00000029034|Vega:OTTMUSG00000010891 +71960 Myh14 MGI:MGI:1919210|Ensembl:ENSMUSG00000030739|Vega:OTTMUSG00000017593 +71962 Gatsl3 MGI:MGI:1919212|Ensembl:ENSMUSG00000020424|Vega:OTTMUSG00000005056 +71963 Cdca4 MGI:MGI:1919213|Ensembl:ENSMUSG00000047832 +71966 Nkiras2 MGI:MGI:1919216|Ensembl:ENSMUSG00000017837|Vega:OTTMUSG00000002025 +71967 Mageb16 MGI:MGI:1919217|Ensembl:ENSMUSG00000046942|Vega:OTTMUSG00000017908 +71968 Wdr73 MGI:MGI:1919218|Ensembl:ENSMUSG00000025722|Vega:OTTMUSG00000024601 +71970 Zbed5 MGI:MGI:1919220|Ensembl:ENSMUSG00000034173|Vega:OTTMUSG00000024021 +71971 Zswim1 MGI:MGI:1919221|Ensembl:ENSMUSG00000017764|Vega:OTTMUSG00000001107 +71972 Dnmbp MGI:MGI:1917352|Ensembl:ENSMUSG00000025195|Vega:OTTMUSG00000061972 +71973 Rbpms2 MGI:MGI:1919223|Ensembl:ENSMUSG00000032387|Vega:OTTMUSG00000062640 +71974 Prmt3 MGI:MGI:1919224|Ensembl:ENSMUSG00000030505|Vega:OTTMUSG00000020564 +71978 Ppp2r2a MGI:MGI:1919228|Ensembl:ENSMUSG00000022052 +71979 Prr23a3 MGI:MGI:1919229|Ensembl:ENSMUSG00000090470|Vega:OTTMUSG00000046360 +71981 Tdrd12 MGI:MGI:1919231|Ensembl:ENSMUSG00000030491|Vega:OTTMUSG00000024875 +71982 Snx10 MGI:MGI:1919232|Ensembl:ENSMUSG00000038301|Vega:OTTMUSG00000023330 +71983 Tmco6 MGI:MGI:1919233|Ensembl:ENSMUSG00000006850 +71984 Sars2 MGI:MGI:1919234|Ensembl:ENSMUSG00000070699|Vega:OTTMUSG00000059067 +71985 Acad10 MGI:MGI:1919235|Ensembl:ENSMUSG00000029456|Vega:OTTMUSG00000023515 +71986 Ddx28 MGI:MGI:1919236|Ensembl:ENSMUSG00000045538|Vega:OTTMUSG00000031189 +71988 Esco2 MGI:MGI:1919238|Ensembl:ENSMUSG00000022034|Vega:OTTMUSG00000024476 +71989 Rpusd4 MGI:MGI:1919239|Ensembl:ENSMUSG00000032044|Vega:OTTMUSG00000033575 +71990 Ddx54 MGI:MGI:1919240|Ensembl:ENSMUSG00000029599|Vega:OTTMUSG00000056254 +71991 Ercc8 MGI:MGI:1919241|Ensembl:ENSMUSG00000021694|Vega:OTTMUSG00000030543 +71994 Cnn3 MGI:MGI:1919244|Ensembl:ENSMUSG00000053931|Vega:OTTMUSG00000054988 +71995 Erv3 MGI:MGI:1919245|Ensembl:ENSMUSG00000037482|Vega:OTTMUSG00000016185 +71996 Fthl17a MGI:MGI:1919246|Ensembl:ENSMUSG00000035491|Vega:OTTMUSG00000017937 +71997 Smg9 MGI:MGI:1919247|Ensembl:ENSMUSG00000002210|Vega:OTTMUSG00000022275 +71998 Slc25a35 MGI:MGI:1919248|Ensembl:ENSMUSG00000018740|Vega:OTTMUSG00000005953 +71999 Fbxo22 MGI:MGI:1926014|Ensembl:ENSMUSG00000032309|Vega:OTTMUSG00000032857 +72000 Lmntd2 MGI:MGI:1919250|Ensembl:ENSMUSG00000025500|Vega:OTTMUSG00000060282 +72002 Slc39a5 MGI:MGI:1919336|Ensembl:ENSMUSG00000039878 +72003 Synpr MGI:MGI:1919253|Ensembl:ENSMUSG00000056296|Vega:OTTMUSG00000027769 +72007 Fndc3b MGI:MGI:1919257|Ensembl:ENSMUSG00000039286|Vega:OTTMUSG00000051189 +72008 Zfyve19 MGI:MGI:1919258|Ensembl:ENSMUSG00000068580|Vega:OTTMUSG00000015764 +72012 1600020E01Rik MGI:MGI:1919262|Ensembl:ENSMUSG00000097048 +72014 Btbd17 MGI:MGI:1919264|Ensembl:ENSMUSG00000000202|Vega:OTTMUSG00000003464 +72016 1600002H07Rik MGI:MGI:1919266|Ensembl:ENSMUSG00000024118|Vega:OTTMUSG00000032971 +72017 Cyb5r1 MGI:MGI:1919267|Ensembl:ENSMUSG00000026456|Vega:OTTMUSG00000023725 +72018 Fundc1 MGI:MGI:1919268|Ensembl:ENSMUSG00000025040|Vega:OTTMUSG00000016945 +72019 1500005C15Rik MGI:MGI:1919269 +72020 Zfp654 MGI:MGI:1919270|Ensembl:ENSMUSG00000047141|Vega:OTTMUSG00000059176 +72022 Slc35f2 MGI:MGI:1919272|Ensembl:ENSMUSG00000042195|Vega:OTTMUSG00000063194 +72023 Cyb561d1 MGI:MGI:1919273|Ensembl:ENSMUSG00000048796|Vega:OTTMUSG00000007192 +72025 1600012P17Rik MGI:MGI:1919275 +72026 Trmu MGI:MGI:1919276|Ensembl:ENSMUSG00000022386|Vega:OTTMUSG00000034977 +72027 Slc39a4 MGI:MGI:1919277|Ensembl:ENSMUSG00000063354 +72029 Cnpy3 MGI:MGI:1919279|Ensembl:ENSMUSG00000023973|Vega:OTTMUSG00000030981 +72030 1600025M17Rik MGI:MGI:1919280|Ensembl:ENSMUSG00000085114 +72033 Tsc22d2 MGI:MGI:1919283|Ensembl:ENSMUSG00000027806|Vega:OTTMUSG00000052593 +72039 Mccc1 MGI:MGI:1919289|Ensembl:ENSMUSG00000027709|Vega:OTTMUSG00000029224 +72040 Cdhr5 MGI:MGI:1919290|Ensembl:ENSMUSG00000025497|Vega:OTTMUSG00000060283 +72041 Alkbh4 MGI:MGI:1919291|Ensembl:ENSMUSG00000039754|Vega:OTTMUSG00000025439 +72042 Cotl1 MGI:MGI:1919292|Ensembl:ENSMUSG00000031827|Vega:OTTMUSG00000061656 +72043 Sulf2 MGI:MGI:1919293|Ensembl:ENSMUSG00000006800|Vega:OTTMUSG00000001130 +72045 Mfsd4b2 MGI:MGI:1919295|Ensembl:ENSMUSG00000039339|Vega:OTTMUSG00000042367 +72046 Urgcp MGI:MGI:1919296|Ensembl:ENSMUSG00000049680|Vega:OTTMUSG00000005098 +72047 Ddx42 MGI:MGI:1919297|Ensembl:ENSMUSG00000020705|Vega:OTTMUSG00000003289 +72049 Tnfrsf13c MGI:MGI:1919299|Ensembl:ENSMUSG00000068105 +72050 Kdelc1 MGI:MGI:1919300|Ensembl:ENSMUSG00000026047|Vega:OTTMUSG00000034049 +72053 Tmub2 MGI:MGI:1919303|Ensembl:ENSMUSG00000034757|Vega:OTTMUSG00000002678 +72054 Cyp4f18 MGI:MGI:1919304|Ensembl:ENSMUSG00000003484|Vega:OTTMUSG00000025159 +72055 Slc38a10 MGI:MGI:1919305|Ensembl:ENSMUSG00000061306|Vega:OTTMUSG00000004103 +72056 1810055G02Rik MGI:MGI:1919306|Ensembl:ENSMUSG00000035372 +72057 Phf10 MGI:MGI:1919307|Ensembl:ENSMUSG00000023883|Vega:OTTMUSG00000035228 +72058 Igsf5 MGI:MGI:1919308|Ensembl:ENSMUSG00000000159|Vega:OTTMUSG00000020392 +72061 2010111I01Rik MGI:MGI:1919311|Ensembl:ENSMUSG00000021458|Vega:OTTMUSG00000030849 +72065 Rap2c MGI:MGI:1919315|Ensembl:ENSMUSG00000050029|Vega:OTTMUSG00000017471 +72068 Cnot2 MGI:MGI:1919318|Ensembl:ENSMUSG00000020166|Vega:OTTMUSG00000035217 +72070 2010313P22Rik MGI:MGI:1919320 +72074 Anks4b MGI:MGI:1919324|Ensembl:ENSMUSG00000030909|Vega:OTTMUSG00000017197 +72075 Ogfr MGI:MGI:1919325|Ensembl:ENSMUSG00000049401|Vega:OTTMUSG00000016333 +72076 Mospd4 MGI:MGI:1919326 +72077 Gcnt3 MGI:MGI:1919327|Ensembl:ENSMUSG00000032226|Vega:OTTMUSG00000062764 +72079 2010013B24Rik MGI:MGI:1919329 +72080 Sapcd2 MGI:MGI:1919330|Ensembl:ENSMUSG00000026955|Vega:OTTMUSG00000012028 +72082 Cyp2c55 MGI:MGI:1919332|Ensembl:ENSMUSG00000025002|Vega:OTTMUSG00000023617 +72083 Mzt2 MGI:MGI:1922845|Ensembl:ENSMUSG00000022671|Vega:OTTMUSG00000028499 +72084 Pigx MGI:MGI:1919334|Ensembl:ENSMUSG00000023791|Vega:OTTMUSG00000025806 +72085 Osgepl1 MGI:MGI:1919335|Ensembl:ENSMUSG00000026096|Vega:OTTMUSG00000021889 +72087 2010015M23Rik MGI:MGI:1919337 +72088 Ush1c MGI:MGI:1919338|Ensembl:ENSMUSG00000030838|Vega:OTTMUSG00000025998 +72090 Entpd8 MGI:MGI:1919340|Ensembl:ENSMUSG00000036813|Vega:OTTMUSG00000011776 +72091 Snhg7 MGI:MGI:1919341 +72092 2010320H13Rik MGI:MGI:1919342 +72093 2010320M18Rik MGI:MGI:1919343 +72094 Ugt2a3 MGI:MGI:1919344|Ensembl:ENSMUSG00000035780|Vega:OTTMUSG00000026792 +72096 Eef1akmt2 MGI:MGI:1919346|Ensembl:ENSMUSG00000030960|Vega:OTTMUSG00000023286 +72097 2010300C02Rik MGI:MGI:1919347|Ensembl:ENSMUSG00000026090|Vega:OTTMUSG00000030326 +72098 Tmem68 MGI:MGI:1919348|Ensembl:ENSMUSG00000028232|Vega:OTTMUSG00000004261 +72102 Dusp11 MGI:MGI:1919352|Ensembl:ENSMUSG00000030002|Vega:OTTMUSG00000023616 +72103 Aplf MGI:MGI:1919353|Ensembl:ENSMUSG00000030051|Vega:OTTMUSG00000057210 +72104 2010106C02Rik MGI:MGI:1919354|Ensembl:ENSMUSG00000100738 +72106 Jmjd8 MGI:MGI:1919356|Ensembl:ENSMUSG00000025736|Vega:OTTMUSG00000029400 +72107 Dscc1 MGI:MGI:1919357|Ensembl:ENSMUSG00000022422|Vega:OTTMUSG00000023435 +72108 Ddhd2 MGI:MGI:1919358|Ensembl:ENSMUSG00000061313|Vega:OTTMUSG00000060634 +72112 Ppp1r14d MGI:MGI:1919362|Ensembl:ENSMUSG00000027317|Vega:OTTMUSG00000015879 +72113 Adck1 MGI:MGI:1919363|Ensembl:ENSMUSG00000021044 +72114 Zbed3 MGI:MGI:1919364|Ensembl:ENSMUSG00000041995 +72117 Naa50 MGI:MGI:1919367|Ensembl:ENSMUSG00000022698|Vega:OTTMUSG00000035124 +72119 Tpx2 MGI:MGI:1919369|Ensembl:ENSMUSG00000027469|Vega:OTTMUSG00000015861 +72121 Dennd2d MGI:MGI:2181193|Ensembl:ENSMUSG00000027901|Vega:OTTMUSG00000023170 +72122 2010308F09Rik MGI:MGI:1919372|Ensembl:ENSMUSG00000100714 +72123 Ccdc71l MGI:MGI:1919373|Ensembl:ENSMUSG00000090946|Vega:OTTMUSG00000035405 +72124 Seh1l MGI:MGI:1919374|Ensembl:ENSMUSG00000079614 +72125 Amer2 MGI:MGI:1919375|Ensembl:ENSMUSG00000021986 +72128 2610008E11Rik MGI:MGI:1919378|Ensembl:ENSMUSG00000060301|Vega:OTTMUSG00000038141 +72129 Pex13 MGI:MGI:1919379|Ensembl:ENSMUSG00000020283|Vega:OTTMUSG00000005277 +72131 2010310C07Rik MGI:MGI:1919381|Ensembl:ENSMUSG00000101268 +72133 Trub1 MGI:MGI:1919383|Ensembl:ENSMUSG00000025086 +72134 2600014E21Rik MGI:MGI:1919384 +72135 Pygo1 MGI:MGI:1919385|Ensembl:ENSMUSG00000034910|Vega:OTTMUSG00000027456 +72136 Chst14 MGI:MGI:1919386|Ensembl:ENSMUSG00000074916|Vega:OTTMUSG00000015639 +72137 Wdsub1 MGI:MGI:1919387|Ensembl:ENSMUSG00000026988|Vega:OTTMUSG00000012813 +72139 2610044O15Rik8 MGI:MGI:1919389|Ensembl:ENSMUSG00000071302|Vega:OTTMUSG00000046629 +72140 Cep89 MGI:MGI:1919390|Ensembl:ENSMUSG00000023072|Vega:OTTMUSG00000024454 +72141 Adpgk MGI:MGI:1919391|Ensembl:ENSMUSG00000025236|Vega:OTTMUSG00000063291 +72144 Slc37a3 MGI:MGI:1919394|Ensembl:ENSMUSG00000029924|Vega:OTTMUSG00000056322 +72145 Wdfy3 MGI:MGI:1096875|Ensembl:ENSMUSG00000043940|Vega:OTTMUSG00000037884 +72146 2810001A02Rik MGI:MGI:1919396 +72147 Zbtb46 MGI:MGI:1919397|Ensembl:ENSMUSG00000027583|Vega:OTTMUSG00000016707 +72148 Tdrp MGI:MGI:1919398|Ensembl:ENSMUSG00000050052|Vega:OTTMUSG00000031434 +72149 Strada MGI:MGI:1919399|Ensembl:ENSMUSG00000069631|Vega:OTTMUSG00000003220 +72151 Rfc5 MGI:MGI:1919401|Ensembl:ENSMUSG00000029363|Vega:OTTMUSG00000025772 +72153 2610020P09Rik MGI:MGI:1919403 +72154 Zfp157 MGI:MGI:1919404|Ensembl:ENSMUSG00000036898|Vega:OTTMUSG00000022795 +72155 Cenpn MGI:MGI:1919405|Ensembl:ENSMUSG00000031756|Vega:OTTMUSG00000061719 +72157 Pgm2 MGI:MGI:97565|Ensembl:ENSMUSG00000025791|Vega:OTTMUSG00000008026 +72159 Gm9726 MGI:MGI:3648149 +72160 Tmem163 MGI:MGI:1919410|Ensembl:ENSMUSG00000026347|Vega:OTTMUSG00000030321 +72162 Dhx36 MGI:MGI:1919412|Ensembl:ENSMUSG00000027770|Vega:OTTMUSG00000025981 +72167 Thumpd2 MGI:MGI:1919417|Ensembl:ENSMUSG00000024246 +72168 Aifm3 MGI:MGI:1919418|Ensembl:ENSMUSG00000022763|Vega:OTTMUSG00000025661 +72169 Trim29 MGI:MGI:1919419|Ensembl:ENSMUSG00000032013|Vega:OTTMUSG00000063156 +72170 Chchd4 MGI:MGI:1919420|Ensembl:ENSMUSG00000034203|Vega:OTTMUSG00000057968 +72171 Shq1 MGI:MGI:1919421|Ensembl:ENSMUSG00000035378|Vega:OTTMUSG00000023548 +72175 Mfsd8 MGI:MGI:1919425|Ensembl:ENSMUSG00000025759|Vega:OTTMUSG00000027548 +72179 Fbxl2 MGI:MGI:1919429|Ensembl:ENSMUSG00000032507|Vega:OTTMUSG00000031906 +72180 Zfp661 MGI:MGI:1919430|Ensembl:ENSMUSG00000034800|Vega:OTTMUSG00000016029 +72181 Nsun4 MGI:MGI:1919431|Ensembl:ENSMUSG00000028706|Vega:OTTMUSG00000008728 +72183 Snx6 MGI:MGI:1919433|Ensembl:ENSMUSG00000005656 +72184 Klhl35 MGI:MGI:1919434|Ensembl:ENSMUSG00000035298|Vega:OTTMUSG00000029805 +72185 Dbndd1 MGI:MGI:1919435|Ensembl:ENSMUSG00000031970|Vega:OTTMUSG00000040147 +72190 2510009E07Rik MGI:MGI:1919440|Ensembl:ENSMUSG00000043391 +72193 Scaf11 MGI:MGI:1919443|Ensembl:ENSMUSG00000033228 +72194 Fbxl20 MGI:MGI:1919444|Ensembl:ENSMUSG00000020883|Vega:OTTMUSG00000002913 +72195 Supt7l MGI:MGI:1919445|Ensembl:ENSMUSG00000053134|Vega:OTTMUSG00000028285 +72197 2610037P13Rik MGI:MGI:1919447 +72198 Skiv2l2 MGI:MGI:1919448|Ensembl:ENSMUSG00000016018 +72199 Mms19 MGI:MGI:1919449|Ensembl:ENSMUSG00000025159|Vega:OTTMUSG00000035800 +72201 Otud6b MGI:MGI:1919451|Ensembl:ENSMUSG00000040550|Vega:OTTMUSG00000004547 +72203 2610507I01Rik MGI:MGI:1919453 +72205 Eml2 MGI:MGI:1919455|Ensembl:ENSMUSG00000040811|Vega:OTTMUSG00000029191 +72206 1700001I21Rik MGI:MGI:1919456 +72207 1700003K11Rik MGI:MGI:1919457 +72208 1700016L21Rik MGI:MGI:1919458|Ensembl:ENSMUSG00000101483 +72210 1700022C07Rik MGI:MGI:1919460 +72211 1700025C18Rik MGI:MGI:1919461|Ensembl:ENSMUSG00000078935|Vega:OTTMUSG00000016557 +72212 1700019H22Rik MGI:MGI:1919462 +72215 1700001P01Rik MGI:MGI:1919465|Ensembl:ENSMUSG00000018543|Vega:OTTMUSG00000002779 +72217 Kbtbd8os MGI:MGI:1919467 +72218 Rab11fip4os2 MGI:MGI:1925439|Ensembl:ENSMUSG00000086569 +72219 Spata31d1a MGI:MGI:1919469|Ensembl:ENSMUSG00000050876 +72221 1700021F07Rik MGI:MGI:1919471|Ensembl:ENSMUSG00000027518|Vega:OTTMUSG00000016241 +72223 1700015P03Rik MGI:MGI:1919473 +72224 1700001J11Rik MGI:MGI:1919474|Ensembl:ENSMUSG00000101963 +72225 1700003M07Rik MGI:MGI:1919475 +72226 1700019L13Rik MGI:MGI:1919476 +72228 1700021L22Rik MGI:MGI:1919478 +72229 1700003G13Rik MGI:MGI:1919479|Ensembl:ENSMUSG00000085831 +72230 Zfp558 MGI:MGI:1921681|Ensembl:ENSMUSG00000074500|Vega:OTTMUSG00000034712 +72231 1700018A23Rik MGI:MGI:1919481|Ensembl:ENSMUSG00000107368 +72233 1700023G08Rik MGI:MGI:1919483 +72234 1700020B03Rik MGI:MGI:1919484 +72235 1700021J08Rik MGI:MGI:1919485 +72236 Tsnaxip1 MGI:MGI:1919486|Ensembl:ENSMUSG00000031893|Vega:OTTMUSG00000062058 +72237 1700007M16Rik MGI:MGI:1919487 +72238 Tbc1d5 MGI:MGI:1919488|Ensembl:ENSMUSG00000023923 +72240 1600014C23Rik MGI:MGI:1919490|Ensembl:ENSMUSG00000094690 +72241 1700006H20Rik MGI:MGI:1919491 +72242 Psg21 MGI:MGI:1891353|Ensembl:ENSMUSG00000070796|Vega:OTTMUSG00000043489 +72243 1700012D01Rik MGI:MGI:1919493|Ensembl:ENSMUSG00000040195 +72244 1600014C10Rik MGI:MGI:1919494 +72245 1700018M17Rik MGI:MGI:1919495 +72246 1700030C12Rik MGI:MGI:1919496 +72247 1700013K18Rik MGI:MGI:1919497 +72248 1700014B07Rik MGI:MGI:1919498 +72249 1700019G24Rik MGI:MGI:1919499|Ensembl:ENSMUSG00000085416 +72250 1700029E06Rik MGI:MGI:1919500 +72252 1700022A21Rik MGI:MGI:1919502|Ensembl:ENSMUSG00000038165 +72254 1700030K09Rik MGI:MGI:1919504|Ensembl:ENSMUSG00000052794|Vega:OTTMUSG00000031775 +72257 1700006H21Rik MGI:MGI:1919507|Ensembl:ENSMUSG00000102000 +72258 Kcnk10 MGI:MGI:1919508|Ensembl:ENSMUSG00000033854 +72259 1700030M09Rik MGI:MGI:1919509|Ensembl:ENSMUSG00000097424 +72263 1700030F04Rik MGI:MGI:1919513|Ensembl:ENSMUSG00000099869 +72264 1700029J03Rik MGI:MGI:1919514|Ensembl:ENSMUSG00000099968 +72265 Tram1 MGI:MGI:1919515|Ensembl:ENSMUSG00000025935|Vega:OTTMUSG00000049113 +72267 Lrrc8e MGI:MGI:1919517|Ensembl:ENSMUSG00000046589|Vega:OTTMUSG00000059343 +72268 1700027F06Rik MGI:MGI:1919518 +72269 Cda MGI:MGI:1919519|Ensembl:ENSMUSG00000028755|Vega:OTTMUSG00000009980 +72271 1700026N04Rik MGI:MGI:1919521 +72273 Smim24 MGI:MGI:1919523|Ensembl:ENSMUSG00000078439|Vega:OTTMUSG00000030397 +72274 1700027H10Rik MGI:MGI:1919524|Ensembl:ENSMUSG00000100799 +72275 2200002D01Rik MGI:MGI:1919525|Ensembl:ENSMUSG00000030587|Vega:OTTMUSG00000025024 +72276 1700025M24Rik MGI:MGI:1919526|Ensembl:ENSMUSG00000100175 +72277 1700030F18Rik MGI:MGI:1919527|Ensembl:ENSMUSG00000045350|Vega:OTTMUSG00000042398 +72278 Ccpg1 MGI:MGI:1196419|Ensembl:ENSMUSG00000034563|Vega:OTTMUSG00000033538 +72280 2210402A03Rik MGI:MGI:1919530 +72281 Sh2d4a MGI:MGI:1919531|Ensembl:ENSMUSG00000053886|Vega:OTTMUSG00000029939 +72282 1810062G17Rik MGI:MGI:1919532|Ensembl:ENSMUSG00000027713|Vega:OTTMUSG00000042654 +72283 1700029B24Rik MGI:MGI:1919533 +72284 Oraov1 MGI:MGI:1919534|Ensembl:ENSMUSG00000031072|Vega:OTTMUSG00000026017 +72285 1810073O08Rik MGI:MGI:1919535 +72286 1700030O20Rik MGI:MGI:1919536|Ensembl:ENSMUSG00000100198 +72287 Plekhf1 MGI:MGI:1919537|Ensembl:ENSMUSG00000074170|Vega:OTTMUSG00000058186 +72288 2210402C17Rik MGI:MGI:1919538 +72289 Malat1 MGI:MGI:1919539|Ensembl:ENSMUSG00000092341 +72290 Lsm11 MGI:MGI:1919540|Ensembl:ENSMUSG00000044847|Vega:OTTMUSG00000005480 +72292 2210009P08Rik MGI:MGI:1919542 +72293 Nkd2 MGI:MGI:1919543|Ensembl:ENSMUSG00000021567|Vega:OTTMUSG00000027729 +72296 Rusc1 MGI:MGI:1919546|Ensembl:ENSMUSG00000041263|Vega:OTTMUSG00000052607 +72297 B3gnt3 MGI:MGI:2152535|Ensembl:ENSMUSG00000031803|Vega:OTTMUSG00000062166 +72301 1810041L15Rik MGI:MGI:1919551|Ensembl:ENSMUSG00000062760|Vega:OTTMUSG00000045912 +72302 1810057I12Rik MGI:MGI:1919552 +72303 Cyp2c65 MGI:MGI:1919553|Ensembl:ENSMUSG00000067231|Vega:OTTMUSG00000028349 +72305 2210404E10Rik MGI:MGI:1919555 +72306 Zfp777 MGI:MGI:1919556|Ensembl:ENSMUSG00000071477|Vega:OTTMUSG00000022127 +72307 2510002D24Rik MGI:MGI:1919557|Ensembl:ENSMUSG00000071632|Vega:OTTMUSG00000026273 +72308 Brf1 MGI:MGI:1919558|Ensembl:ENSMUSG00000011158 +72309 Tmem158 MGI:MGI:1919559|Ensembl:ENSMUSG00000054871|Vega:OTTMUSG00000062842 +72310 Nkg7 MGI:MGI:1931250|Ensembl:ENSMUSG00000004612|Vega:OTTMUSG00000058528 +72311 2310004O12Rik MGI:MGI:1919561 +72313 Fryl MGI:MGI:1919563|Ensembl:ENSMUSG00000070733|Vega:OTTMUSG00000024870 +72315 Ccdc74a MGI:MGI:1919565|Ensembl:ENSMUSG00000041617|Vega:OTTMUSG00000044408 +72316 2310008N11Rik MGI:MGI:1919566|Ensembl:ENSMUSG00000100335 +72317 Asb17os MGI:MGI:1919567|Ensembl:ENSMUSG00000086438 +72318 Cyth4 MGI:MGI:2441702|Ensembl:ENSMUSG00000018008 +72320 Kif1bp MGI:MGI:1919570|Ensembl:ENSMUSG00000036955|Vega:OTTMUSG00000031220 +72322 Xpo5 MGI:MGI:1913789|Ensembl:ENSMUSG00000067150 +72323 Asb6 MGI:MGI:1919573|Ensembl:ENSMUSG00000039483|Vega:OTTMUSG00000011879 +72324 Plxdc1 MGI:MGI:1919574|Ensembl:ENSMUSG00000017417|Vega:OTTMUSG00000002911 +72325 Vps9d1 MGI:MGI:1914143|Ensembl:ENSMUSG00000001062|Vega:OTTMUSG00000030130 +72326 2500004C02Rik MGI:MGI:1919576|Ensembl:ENSMUSG00000073236 +72330 Klhl40 MGI:MGI:1919580|Ensembl:ENSMUSG00000074001|Vega:OTTMUSG00000062670 +72331 2310021N16Rik MGI:MGI:1919581 +72332 2610001N11Rik MGI:MGI:1919582 +72333 Palld MGI:MGI:1919583|Ensembl:ENSMUSG00000058056|Vega:OTTMUSG00000031055 +72338 Wdr89 MGI:MGI:1919588|Ensembl:ENSMUSG00000045690|Vega:OTTMUSG00000047041 +72340 2010009K17Rik MGI:MGI:1919590|Ensembl:ENSMUSG00000100860 +72341 Elp6 MGI:MGI:1919349|Ensembl:ENSMUSG00000054836|Vega:OTTMUSG00000051577 +72342 Gm9727 MGI:MGI:3779431 +72343 2600002B07Rik MGI:MGI:1919593 +72344 Usp36 MGI:MGI:1919594|Ensembl:ENSMUSG00000033909|Vega:OTTMUSG00000003884 +72345 Amer1 MGI:MGI:1919595|Ensembl:ENSMUSG00000050332|Vega:OTTMUSG00000018053 +72347 2210011G09Rik MGI:MGI:1919597 +72349 Dusp3 MGI:MGI:1919599|Ensembl:ENSMUSG00000003518|Vega:OTTMUSG00000002139 +72350 Zc2hc1c MGI:MGI:1919600|Ensembl:ENSMUSG00000045064|Vega:OTTMUSG00000027676 +72351 Ptar1 MGI:MGI:1921875|Ensembl:ENSMUSG00000074925 +72354 Ttc4 MGI:MGI:1919604|Ensembl:ENSMUSG00000025413|Vega:OTTMUSG00000008164 +72355 Cdpf1 MGI:MGI:1919605|Ensembl:ENSMUSG00000064284|Vega:OTTMUSG00000033736 +72357 2210016L21Rik MGI:MGI:1919607|Ensembl:ENSMUSG00000029559|Vega:OTTMUSG00000014614 +72358 2210411A11Rik MGI:MGI:1919608 +72359 2210020O09Rik MGI:MGI:1919609 +72361 Ces2g MGI:MGI:1919611|Ensembl:ENSMUSG00000031877|Vega:OTTMUSG00000061989 +72365 2210011K15Rik MGI:MGI:1919615 +72368 Borcs8 MGI:MGI:1919618|Ensembl:ENSMUSG00000002345|Vega:OTTMUSG00000022206 +72371 2210408I21Rik MGI:MGI:1919621|Ensembl:ENSMUSG00000071252|Vega:OTTMUSG00000035272 +72372 2210411G17Rik MGI:MGI:1919622 +72373 Psca MGI:MGI:1919623|Ensembl:ENSMUSG00000022598|Vega:OTTMUSG00000045264 +72374 2210416J07Rik MGI:MGI:1919624 +72375 2210412B16Rik MGI:MGI:1919625 +72379 2210409O19Rik MGI:MGI:1919629 +72381 2210409E12Rik MGI:MGI:1919631|Ensembl:ENSMUSG00000081766 +72383 Cnfn MGI:MGI:1919633|Ensembl:ENSMUSG00000063651|Vega:OTTMUSG00000058247 +72386 2610035D17Rik MGI:MGI:1919636|Ensembl:ENSMUSG00000087259 +72388 Ripk4 MGI:MGI:1919638|Ensembl:ENSMUSG00000005251|Vega:OTTMUSG00000019977 +72389 2310050P20Rik MGI:MGI:1919639 +72391 Cdkn3 MGI:MGI:1919641|Ensembl:ENSMUSG00000037628 +72392 Tmem175 MGI:MGI:1919642|Ensembl:ENSMUSG00000013495|Vega:OTTMUSG00000026815 +72393 Faim2 MGI:MGI:1919643|Ensembl:ENSMUSG00000023011 +72395 2610028E06Rik MGI:MGI:1919645|Ensembl:ENSMUSG00000085562 +72397 Rbm12b1 MGI:MGI:1919647|Ensembl:ENSMUSG00000046667|Vega:OTTMUSG00000004571 +72399 Brap MGI:MGI:1919649|Ensembl:ENSMUSG00000029458|Vega:OTTMUSG00000023519 +72400 Pinx1 MGI:MGI:1919650|Ensembl:ENSMUSG00000021958 +72401 Slc43a1 MGI:MGI:1931352|Ensembl:ENSMUSG00000027075|Vega:OTTMUSG00000013724 +72404 Wdr44 MGI:MGI:1919654|Ensembl:ENSMUSG00000036769|Vega:OTTMUSG00000016985 +72406 2310081O03Rik MGI:MGI:1919656 +72411 3300002I10Rik MGI:MGI:1919661 +72413 Kcnmb2 MGI:MGI:1919663|Ensembl:ENSMUSG00000037610|Vega:OTTMUSG00000026466 +72415 Sgo1 MGI:MGI:1919665|Ensembl:ENSMUSG00000023940|Vega:OTTMUSG00000024480 +72416 Lrpprc MGI:MGI:1919666|Ensembl:ENSMUSG00000024120|Vega:OTTMUSG00000030887 +72421 Ttc30b MGI:MGI:1919671|Ensembl:ENSMUSG00000075273|Vega:OTTMUSG00000015168 +72425 Katnbl1 MGI:MGI:1919675|Ensembl:ENSMUSG00000027132|Vega:OTTMUSG00000015139 +72429 Dnajc25 MGI:MGI:1919679|Ensembl:ENSMUSG00000070972|Vega:OTTMUSG00000007629 +72431 Ceacam18 MGI:MGI:1919681|Ensembl:ENSMUSG00000030472|Vega:OTTMUSG00000058305 +72432 Spink5 MGI:MGI:1919682|Ensembl:ENSMUSG00000055561|Vega:OTTMUSG00000016338 +72433 Rab38 MGI:MGI:1919683|Ensembl:ENSMUSG00000030559|Vega:OTTMUSG00000025016 +72434 Lypd3 MGI:MGI:1919684|Ensembl:ENSMUSG00000057454|Vega:OTTMUSG00000058226 +72435 2310065H11Rik MGI:MGI:1919685 +72439 2610007B07Rik MGI:MGI:1919689 +72440 Rhno1 MGI:MGI:1915315|Ensembl:ENSMUSG00000048668|Vega:OTTMUSG00000023774 +72446 Prr5l MGI:MGI:1919696|Ensembl:ENSMUSG00000032841|Vega:OTTMUSG00000015047 +72454 Ccdc71 MGI:MGI:1919704|Ensembl:ENSMUSG00000049305|Vega:OTTMUSG00000050823 +72459 Htatsf1 MGI:MGI:1919709|Ensembl:ENSMUSG00000067873|Vega:OTTMUSG00000017792 +72460 2610011E03Rik MGI:MGI:1919710 +72461 Prcp MGI:MGI:1919711|Ensembl:ENSMUSG00000061119|Vega:OTTMUSG00000059925 +72462 Rrp1b MGI:MGI:1919712|Ensembl:ENSMUSG00000058392|Vega:OTTMUSG00000031369 +72465 Zfp131 MGI:MGI:1919715|Ensembl:ENSMUSG00000094870 +72468 2610204G07Rik MGI:MGI:1919718 +72469 Plcd3 MGI:MGI:107451|Ensembl:ENSMUSG00000020937|Vega:OTTMUSG00000003295 +72472 Slc16a10 MGI:MGI:1919722|Ensembl:ENSMUSG00000019838|Vega:OTTMUSG00000063428 +72475 Ssbp3 MGI:MGI:1919725|Ensembl:ENSMUSG00000061887|Vega:OTTMUSG00000008276 +72477 Tmem87b MGI:MGI:1919727|Ensembl:ENSMUSG00000014353|Vega:OTTMUSG00000015355 +72479 Hsdl2 MGI:MGI:1919729|Ensembl:ENSMUSG00000028383|Vega:OTTMUSG00000007335 +72480 Tspyl4 MGI:MGI:106393|Ensembl:ENSMUSG00000039485|Vega:OTTMUSG00000023254 +72481 2610203C22Rik MGI:MGI:1919731|Ensembl:ENSMUSG00000079671 +72482 Acbd6 MGI:MGI:1919732|Ensembl:ENSMUSG00000033701|Vega:OTTMUSG00000034796 +72484 2610300M13Rik MGI:MGI:1919734 +72486 Rnf219 MGI:MGI:1919736|Ensembl:ENSMUSG00000022120 +72489 2610301H18Rik MGI:MGI:1919739 +72493 2610202C22Rik MGI:MGI:1919743 +72495 2610206C17Rik MGI:MGI:1919745|Ensembl:ENSMUSG00000085236 +72500 Ier5l MGI:MGI:1919750|Ensembl:ENSMUSG00000089762|Vega:OTTMUSG00000016799 +72502 Cwf19l1 MGI:MGI:1919752|Ensembl:ENSMUSG00000025200 +72503 2610507B11Rik MGI:MGI:1919753|Ensembl:ENSMUSG00000010277|Vega:OTTMUSG00000000100 +72504 Taf4b MGI:MGI:2152345|Ensembl:ENSMUSG00000054321 +72505 2610319H10Rik MGI:MGI:1919755 +72507 Dzip1l MGI:MGI:1919757|Ensembl:ENSMUSG00000037784|Vega:OTTMUSG00000023471 +72508 Rps6kb1 MGI:MGI:1270849|Ensembl:ENSMUSG00000020516|Vega:OTTMUSG00000001198 +72511 2610316D01Rik MGI:MGI:1919761|Ensembl:ENSMUSG00000097040 +72512 Tmem173 MGI:MGI:1919762|Ensembl:ENSMUSG00000024349 +72514 Fgfbp3 MGI:MGI:1919764|Ensembl:ENSMUSG00000047632|Vega:OTTMUSG00000032869 +72515 Wdr43 MGI:MGI:1919765|Ensembl:ENSMUSG00000041057 +72518 2610307P16Rik MGI:MGI:1919768 +72519 Tmem55a MGI:MGI:1919769|Ensembl:ENSMUSG00000028221|Vega:OTTMUSG00000004553 +72522 Atxn7l2 MGI:MGI:1919772|Ensembl:ENSMUSG00000048997|Vega:OTTMUSG00000007195 +72523 2700005E23Rik MGI:MGI:1919773 +72527 2610529L02Rik MGI:MGI:1919777 +72528 2700003A03Rik MGI:MGI:1919778 +72531 2610317O13Rik MGI:MGI:1919781 +72535 Aldh1b1 MGI:MGI:1919785|Ensembl:ENSMUSG00000035561|Vega:OTTMUSG00000006730 +72536 Tagap MGI:MGI:3615484|Ensembl:ENSMUSG00000033450|Vega:OTTMUSG00000034757 +72539 2700008E08Rik MGI:MGI:1919789 +72541 2700003L17Rik MGI:MGI:1919791 +72542 Pgam5 MGI:MGI:1919792|Ensembl:ENSMUSG00000029500|Vega:OTTMUSG00000026211 +72543 Mvb12b MGI:MGI:1919793|Ensembl:ENSMUSG00000038740|Vega:OTTMUSG00000011912 +72544 Exosc6 MGI:MGI:1919794|Ensembl:ENSMUSG00000109941|Vega:OTTMUSG00000060250 +72547 2700008L21Rik MGI:MGI:1919797 +72549 Reep4 MGI:MGI:1919799|Ensembl:ENSMUSG00000033589 +72552 Hsdl1 MGI:MGI:1919802|Ensembl:ENSMUSG00000034189|Vega:OTTMUSG00000061640 +72554 Utp14a MGI:MGI:1919804|Ensembl:ENSMUSG00000063785|Vega:OTTMUSG00000017516 +72555 Shisa9 MGI:MGI:1919805|Ensembl:ENSMUSG00000022494|Vega:OTTMUSG00000044348 +72556 Zfp566 MGI:MGI:1919806|Ensembl:ENSMUSG00000078768|Vega:OTTMUSG00000044415 +72559 2700026D01Rik MGI:MGI:1919809 +72560 Naalad2 MGI:MGI:1919810|Ensembl:ENSMUSG00000043943|Vega:OTTMUSG00000036485 +72562 Pcbd2 MGI:MGI:1919812|Ensembl:ENSMUSG00000021496 +72563 2700068H02Rik MGI:MGI:1919813 +72564 2700063P09Rik MGI:MGI:1919814 +72565 Uaca MGI:MGI:1919815|Ensembl:ENSMUSG00000034485|Vega:OTTMUSG00000063338 +72567 Bclaf1 MGI:MGI:1917580|Ensembl:ENSMUSG00000037608|Vega:OTTMUSG00000049448 +72568 Lin9 MGI:MGI:1919818|Ensembl:ENSMUSG00000058729|Vega:OTTMUSG00000050451 +72569 Bbs5 MGI:MGI:1919819|Ensembl:ENSMUSG00000063145|Vega:OTTMUSG00000012987 +72572 Spats2 MGI:MGI:1919822|Ensembl:ENSMUSG00000051934 +72575 C430049B03Rik MGI:MGI:1924903 +72578 2700054A10Rik MGI:MGI:1919828|Ensembl:ENSMUSG00000038347 +72580 Zufsp MGI:MGI:1919830|Ensembl:ENSMUSG00000039531 +72584 Cul4b MGI:MGI:1919834|Ensembl:ENSMUSG00000031095|Vega:OTTMUSG00000017236 +72585 Lypd1 MGI:MGI:1919835|Ensembl:ENSMUSG00000026344|Vega:OTTMUSG00000030265 +72587 Pan3 MGI:MGI:1919837|Ensembl:ENSMUSG00000029647|Vega:OTTMUSG00000040042 +72588 2700012I20Rik MGI:MGI:1919838 +72590 Ppme1 MGI:MGI:1919840|Ensembl:ENSMUSG00000030718|Vega:OTTMUSG00000059188 +72591 2700022O18Rik MGI:MGI:1919841 +72595 2700054A04Rik MGI:MGI:1919845 +72596 2700054B07Rik MGI:MGI:1919846 +72599 Pdia5 MGI:MGI:1919849|Ensembl:ENSMUSG00000022844 +72603 2700033N17Rik MGI:MGI:1919853 +72605 Car10 MGI:MGI:1919855|Ensembl:ENSMUSG00000056158|Vega:OTTMUSG00000001341 +72607 Usp13 MGI:MGI:1919857|Ensembl:ENSMUSG00000056900|Vega:OTTMUSG00000023838 +72608 2700069I18Rik MGI:MGI:1919858 +72609 2700070H01Rik MGI:MGI:1919859 +72611 Zfp655 MGI:MGI:1919861|Ensembl:ENSMUSG00000007812|Vega:OTTMUSG00000055029 +72612 Hpf1 MGI:MGI:1919862|Ensembl:ENSMUSG00000038005|Vega:OTTMUSG00000031399 +72614 Pih1d2 MGI:MGI:1919864|Ensembl:ENSMUSG00000000167|Vega:OTTMUSG00000033526 +72615 Anks3 MGI:MGI:1919865|Ensembl:ENSMUSG00000022515 +72617 2700088M07Rik MGI:MGI:1919867 +72621 Pdzd11 MGI:MGI:1919871|Ensembl:ENSMUSG00000015668|Vega:OTTMUSG00000018288 +72626 2700078F05Rik MGI:MGI:1919876 +72628 Hoxaas3 MGI:MGI:1919878|Ensembl:ENSMUSG00000085696 +72630 Hspa12b MGI:MGI:1919880|Ensembl:ENSMUSG00000074793|Vega:OTTMUSG00000015727 +72632 Smim18 MGI:MGI:1919882|Ensembl:ENSMUSG00000094500|Vega:OTTMUSG00000049708 +72633 2810019C22Rik MGI:MGI:1919883 +72634 Tdrkh MGI:MGI:1919884|Ensembl:ENSMUSG00000041912|Vega:OTTMUSG00000052040 +72635 Lins1 MGI:MGI:1919885|Ensembl:ENSMUSG00000053091|Vega:OTTMUSG00000031938 +72638 2810017D21Rik MGI:MGI:1919888 +72640 Mex3a MGI:MGI:1919890|Ensembl:ENSMUSG00000074480|Vega:OTTMUSG00000037635 +72647 2700089I24Rik MGI:MGI:1919897|Ensembl:ENSMUSG00000100119 +72648 Smc2os MGI:MGI:1919898|Ensembl:ENSMUSG00000085763 +72649 Tmem209 MGI:MGI:1919899|Ensembl:ENSMUSG00000029782|Vega:OTTMUSG00000014358 +72650 2810006K23Rik MGI:MGI:1919900|Ensembl:ENSMUSG00000047635|Vega:OTTMUSG00000024433 +72654 Ccdc12 MGI:MGI:1919904|Ensembl:ENSMUSG00000019659|Vega:OTTMUSG00000052492 +72655 Snhg5 MGI:MGI:1919905|Ensembl:ENSMUSG00000097195 +72656 Ints8 MGI:MGI:1919906|Ensembl:ENSMUSG00000040738|Vega:OTTMUSG00000004593 +72657 Selenoh MGI:MGI:1919907|Ensembl:ENSMUSG00000076437|Vega:OTTMUSG00000013495 +72658 2700097O09Rik MGI:MGI:1919908|Ensembl:ENSMUSG00000062198|Vega:OTTMUSG00000033589 +72661 Serp2 MGI:MGI:1919911|Ensembl:ENSMUSG00000052584 +72662 Dis3 MGI:MGI:1919912|Ensembl:ENSMUSG00000033166 +72665 2810039B14Rik MGI:MGI:1919915 +72666 2810047J09Rik MGI:MGI:1919916 +72667 Zfp444 MGI:MGI:1923365|Ensembl:ENSMUSG00000044876|Vega:OTTMUSG00000022336 +72668 Skida1 MGI:MGI:1919918|Ensembl:ENSMUSG00000054074|Vega:OTTMUSG00000011457 +72669 2810032G03Rik MGI:MGI:1919919 +72671 2810048H02Rik MGI:MGI:1919921 +72672 Zfp518a MGI:MGI:1919922|Ensembl:ENSMUSG00000049164 +72674 Adipor1 MGI:MGI:1919924|Ensembl:ENSMUSG00000026457|Vega:OTTMUSG00000021808 +72677 2810049E08Rik MGI:MGI:1919927|Ensembl:ENSMUSG00000100891 +72685 Dnajc6 MGI:MGI:1919935|Ensembl:ENSMUSG00000028528|Vega:OTTMUSG00000008458 +72689 2810047F03Rik MGI:MGI:1919939 +72690 Grrp1 MGI:MGI:1919940|Ensembl:ENSMUSG00000050105|Vega:OTTMUSG00000010607 +72691 Calhm2 MGI:MGI:1919941|Ensembl:ENSMUSG00000033033|Vega:OTTMUSG00000033093 +72692 Hnrnpll MGI:MGI:1919942|Ensembl:ENSMUSG00000024095|Vega:OTTMUSG00000044621 +72693 Zcchc12 MGI:MGI:1919943|Ensembl:ENSMUSG00000036699|Vega:OTTMUSG00000017218 +72694 2810036E18Rik MGI:MGI:1919944 +72697 2810043O03Rik MGI:MGI:1919947 +72699 Lime1 MGI:MGI:1919949|Ensembl:ENSMUSG00000090077|Vega:OTTMUSG00000016651 +72701 Zfp618 MGI:MGI:1919950|Ensembl:ENSMUSG00000028358|Vega:OTTMUSG00000000241 +72709 C1qtnf6 MGI:MGI:1919959|Ensembl:ENSMUSG00000022440|Vega:OTTMUSG00000020978 +72711 2810037O22Rik MGI:MGI:1919961 +72712 2810038L03Rik MGI:MGI:1919962 +72713 Angptl1 MGI:MGI:1919963|Ensembl:ENSMUSG00000033544|Vega:OTTMUSG00000022614 +72716 2810047C21Rik1 MGI:MGI:1919966 +72719 2810040C05Rik MGI:MGI:1919969 +72720 Zfp248 MGI:MGI:1919970|Ensembl:ENSMUSG00000030145|Vega:OTTMUSG00000034568 +72722 Fam98a MGI:MGI:1919972|Ensembl:ENSMUSG00000002017|Vega:OTTMUSG00000032863 +72723 Zfp74 MGI:MGI:107784|Ensembl:ENSMUSG00000059975|Vega:OTTMUSG00000022409 +72726 Tbcc MGI:MGI:1919976|Ensembl:ENSMUSG00000036430|Vega:OTTMUSG00000063277 +72727 B3gat3 MGI:MGI:1919977|Ensembl:ENSMUSG00000071649 +72729 Cdc42se2 MGI:MGI:1919979|Ensembl:ENSMUSG00000052298|Vega:OTTMUSG00000005677 +72731 2810410P21Rik MGI:MGI:1919981 +72735 Eldr MGI:MGI:1919985 +72736 Tmx1 MGI:MGI:1919986|Ensembl:ENSMUSG00000021072|Vega:OTTMUSG00000034933 +72739 Zkscan3 MGI:MGI:1919989|Ensembl:ENSMUSG00000021327|Vega:OTTMUSG00000000416 +72740 2810421E14Rik MGI:MGI:1919990 +72745 Tmem161b MGI:MGI:1919995|Ensembl:ENSMUSG00000035762|Vega:OTTMUSG00000044482 +72747 Ttc39c MGI:MGI:1919997|Ensembl:ENSMUSG00000024424|Vega:OTTMUSG00000028186 +72748 Hdhd3 MGI:MGI:1919998|Ensembl:ENSMUSG00000038422|Vega:OTTMUSG00000000236 +72749 Tonsl MGI:MGI:1919999|Ensembl:ENSMUSG00000059323|Vega:OTTMUSG00000035250 +72750 Fam117b MGI:MGI:1920000|Ensembl:ENSMUSG00000041040|Vega:OTTMUSG00000020914 +72753 2810442N19Rik MGI:MGI:1920003|Ensembl:ENSMUSG00000090260 +72754 Arhgef10l MGI:MGI:1920004|Ensembl:ENSMUSG00000040964|Vega:OTTMUSG00000009985 +72759 Tmem135 MGI:MGI:1920009|Ensembl:ENSMUSG00000039428|Vega:OTTMUSG00000030735 +72763 2810439L12Rik MGI:MGI:1920013 +72767 2810427A07Rik MGI:MGI:1920017 +72772 Rint1 MGI:MGI:1916233|Ensembl:ENSMUSG00000028999|Vega:OTTMUSG00000028512 +72773 2810449G22Rik MGI:MGI:1920023 +72774 Neil1 MGI:MGI:1920024|Ensembl:ENSMUSG00000032298|Vega:OTTMUSG00000045268 +72775 Fance MGI:MGI:1920025|Ensembl:ENSMUSG00000007570|Vega:OTTMUSG00000023386 +72776 Sass6 MGI:MGI:1920026|Ensembl:ENSMUSG00000027959|Vega:OTTMUSG00000022737 +72777 2810455B08Rik MGI:MGI:1920027 +72778 Dnajc22 MGI:MGI:1920028|Ensembl:ENSMUSG00000038009|Vega:OTTMUSG00000028182 +72780 Rspo3 MGI:MGI:1920030|Ensembl:ENSMUSG00000019880|Vega:OTTMUSG00000063677 +72781 2810468A05Rik MGI:MGI:1920031 +72784 2810452K05Rik MGI:MGI:1920034 +72785 2810474C18Rik MGI:MGI:1920035 +72787 Ndc1 MGI:MGI:1920037|Ensembl:ENSMUSG00000028614|Vega:OTTMUSG00000008842 +72789 Veph1 MGI:MGI:1920039|Ensembl:ENSMUSG00000027831|Vega:OTTMUSG00000043594 +72792 2810459M11Rik MGI:MGI:1920042|Ensembl:ENSMUSG00000026227|Vega:OTTMUSG00000022123 +72795 Ttc19 MGI:MGI:1920045|Ensembl:ENSMUSG00000042298|Vega:OTTMUSG00000005850 +72801 2810488O17Rik MGI:MGI:1920051 +72804 9130017K11Rik MGI:MGI:1926030 +72805 Zfp839 MGI:MGI:1920055|Ensembl:ENSMUSG00000021271 +72807 Zfp429 MGI:MGI:1920057|Ensembl:ENSMUSG00000078994|Vega:OTTMUSG00000042790 +72810 2810455D13Rik MGI:MGI:1920060 +72813 2810454H06Rik MGI:MGI:1920063|Ensembl:ENSMUSG00000100876 +72818 2810471M01Rik MGI:MGI:1920068|Ensembl:ENSMUSG00000084966 +72820 2810461L16Rik MGI:MGI:1920070 +72821 Scn2b MGI:MGI:106921|Ensembl:ENSMUSG00000070304|Vega:OTTMUSG00000063452 +72822 2810455O05Rik MGI:MGI:1920072 +72823 Pard3b MGI:MGI:1919301|Ensembl:ENSMUSG00000052062|Vega:OTTMUSG00000002383 +72824 2810457G06Rik MGI:MGI:1920074 +72825 Mon1a MGI:MGI:1920075|Ensembl:ENSMUSG00000032583|Vega:OTTMUSG00000050788 +72826 Fam76b MGI:MGI:1920076|Ensembl:ENSMUSG00000037808|Vega:OTTMUSG00000023308 +72828 Ubash3b MGI:MGI:1920078|Ensembl:ENSMUSG00000032020|Vega:OTTMUSG00000025903 +72831 Dhx30 MGI:MGI:1920081|Ensembl:ENSMUSG00000032480|Vega:OTTMUSG00000034137 +72832 Crtac1 MGI:MGI:1920082|Ensembl:ENSMUSG00000042401 +72834 2810468N07Rik MGI:MGI:1920084|Ensembl:ENSMUSG00000091475 +72836 Pot1b MGI:MGI:1920086|Ensembl:ENSMUSG00000024174 +72837 2810487C13Rik MGI:MGI:1920087 +72840 2810481J17Rik MGI:MGI:1920090 +72843 Prdm4 MGI:MGI:1920093|Ensembl:ENSMUSG00000035529 +72844 Kctd17 MGI:MGI:1920094|Ensembl:ENSMUSG00000033287|Vega:OTTMUSG00000034897 +72845 2900024I21Rik MGI:MGI:1920095 +72850 2900024J01Rik MGI:MGI:1920100 +72852 Mblac2 MGI:MGI:1920102|Ensembl:ENSMUSG00000051098 +72854 2900034C19Rik MGI:MGI:1920104 +72855 2900024D18Rik MGI:MGI:1920105 +72860 2900017G11Rik MGI:MGI:1920110 +72861 2900005I04Rik MGI:MGI:1920111 +72864 2900018N21Rik MGI:MGI:1920114 +72865 Cxx1c MGI:MGI:1920115|Ensembl:ENSMUSG00000051851|Vega:OTTMUSG00000017366 +72867 2900036C06Rik MGI:MGI:1920117 +72868 2900022P04Rik MGI:MGI:1920118 +72873 Bbof1 MGI:MGI:1920123|Ensembl:ENSMUSG00000057265|Vega:OTTMUSG00000027586 +72876 2900009J20Rik MGI:MGI:1920126 +72877 2900003A17Rik MGI:MGI:1920127 +72880 2900027M19Rik MGI:MGI:1920130 +72881 Zdhhc4 MGI:MGI:1920131|Ensembl:ENSMUSG00000001844|Vega:OTTMUSG00000022896 +72883 2900035I09Rik MGI:MGI:1920133 +72886 Ccdc94 MGI:MGI:1920136|Ensembl:ENSMUSG00000003208 +72891 Xlr4c MGI:MGI:3574099|Ensembl:ENSMUSG00000031362|Vega:OTTMUSG00000017663 +72892 2900018K06Rik MGI:MGI:1920142 +72893 2900040C04Rik MGI:MGI:1920143 +72895 Setd5 MGI:MGI:1920145|Ensembl:ENSMUSG00000034269|Vega:OTTMUSG00000017316 +72897 2900006B11Rik MGI:MGI:1920147 +72898 Asphd2 MGI:MGI:1920148|Ensembl:ENSMUSG00000029348|Vega:OTTMUSG00000054330 +72899 Macrod2 MGI:MGI:1920149|Ensembl:ENSMUSG00000068205|Vega:OTTMUSG00000015597 +72900 Ndufv2 MGI:MGI:1920150|Ensembl:ENSMUSG00000024099|Vega:OTTMUSG00000016284 +72901 2900011F02Rik MGI:MGI:1920151 +72902 Spock3 MGI:MGI:1920152|Ensembl:ENSMUSG00000054162|Vega:OTTMUSG00000031630 +72905 2900035J10Rik MGI:MGI:1920155 +72906 2900042A17Rik MGI:MGI:1920156 +72912 2900016D18Rik MGI:MGI:1920162 +72913 2900006A17Rik MGI:MGI:1920163 +72914 2900012M01Rik MGI:MGI:1920164 +72915 2900017F05Rik MGI:MGI:1920165 +72918 2900019E01Rik MGI:MGI:1920168 +72919 2900019A20Rik MGI:MGI:1920169 +72920 2900021C02Rik MGI:MGI:1920170 +72925 March1 MGI:MGI:1920175|Ensembl:ENSMUSG00000036469|Vega:OTTMUSG00000016640 +72927 Hepacam MGI:MGI:1920177|Ensembl:ENSMUSG00000046240|Vega:OTTMUSG00000016793 +72930 Ppp2r2b MGI:MGI:1920180|Ensembl:ENSMUSG00000024500|Vega:OTTMUSG00000028098 +72931 Swi5 MGI:MGI:1920181|Ensembl:ENSMUSG00000044627|Vega:OTTMUSG00000012956 +72933 2900011G08Rik MGI:MGI:1920183 +72934 2900006G07Rik MGI:MGI:1920184 +72935 Ddx41 MGI:MGI:1920185|Ensembl:ENSMUSG00000021494 +72938 Hspb11 MGI:MGI:1920188|Ensembl:ENSMUSG00000063172|Vega:OTTMUSG00000008694 +72940 2900022M12Rik MGI:MGI:1920190 +72941 2900042E19Rik MGI:MGI:1920191 +72942 2900045O03Rik MGI:MGI:1920192 +72943 2900018E21Rik MGI:MGI:1920193 +72946 Lrrc47 MGI:MGI:1920196|Ensembl:ENSMUSG00000029028|Vega:OTTMUSG00000010507 +72947 Phykpl MGI:MGI:1920197|Ensembl:ENSMUSG00000020359|Vega:OTTMUSG00000005604 +72948 Tppp MGI:MGI:1920198|Ensembl:ENSMUSG00000021573|Vega:OTTMUSG00000027757 +72949 Ccnt2 MGI:MGI:1920199|Ensembl:ENSMUSG00000026349|Vega:OTTMUSG00000021611 +72951 2900022M07Rik MGI:MGI:1920201 +72953 2900042K21Rik MGI:MGI:1920203 +72956 2900040J22Rik MGI:MGI:1920206 +72958 Zfp493 MGI:MGI:1920208|Ensembl:ENSMUSG00000090659|Vega:OTTMUSG00000042804 +72960 Top1mt MGI:MGI:1920210|Ensembl:ENSMUSG00000000934|Vega:OTTMUSG00000028073 +72961 Slc17a7 MGI:MGI:1920211|Ensembl:ENSMUSG00000070570|Vega:OTTMUSG00000058649 +72962 Tymp MGI:MGI:1920212|Ensembl:ENSMUSG00000022615 +72964 2900056B19Rik MGI:MGI:1920214 +72965 2900064B18Rik MGI:MGI:1920215 +72968 2900069G24Rik MGI:MGI:1920218 +72972 Ccser2 MGI:MGI:101859|Ensembl:ENSMUSG00000058690|Vega:OTTMUSG00000044419 +72973 Fbxo47 MGI:MGI:1920223|Ensembl:ENSMUSG00000070336|Vega:OTTMUSG00000002775 +72975 2900063K03Rik MGI:MGI:1920225 +72976 2900064K03Rik MGI:MGI:1920226 +72978 Cnih3 MGI:MGI:1920228|Ensembl:ENSMUSG00000026514|Vega:OTTMUSG00000034937 +72981 Thap12 MGI:MGI:1920231|Ensembl:ENSMUSG00000030753|Vega:OTTMUSG00000023004 +72982 Tmem138 MGI:MGI:1920232|Ensembl:ENSMUSG00000024666 +72983 2900052O17Rik MGI:MGI:1920233 +72987 2900057C01Rik MGI:MGI:1920237 +72989 2900074G08Rik MGI:MGI:1920239 +72991 2900075N08Rik MGI:MGI:1920241 +72993 Appl1 MGI:MGI:1920243|Ensembl:ENSMUSG00000040760|Vega:OTTMUSG00000016350 +72994 2900046H12Rik MGI:MGI:1920244 +72997 Kantr MGI:MGI:1920247|Ensembl:ENSMUSG00000087403 +72999 Insig2 MGI:MGI:1920249|Ensembl:ENSMUSG00000003721|Vega:OTTMUSG00000034839 +73001 2900055J20Rik MGI:MGI:1920251|Ensembl:ENSMUSG00000071860 +73002 2900076A13Rik MGI:MGI:1920252 +73004 2900078I11Rik MGI:MGI:1920254 +73005 2900072G11Rik MGI:MGI:1920255 +73008 2900073C16Rik MGI:MGI:1920258 +73009 2900057B20Rik MGI:MGI:1920259 +73010 Gpr22 MGI:MGI:1920260|Ensembl:ENSMUSG00000044067|Vega:OTTMUSG00000022806 +73012 2900072D07Rik MGI:MGI:1920262 +73014 2900054C15Rik MGI:MGI:1920264 +73016 Kremen2 MGI:MGI:1920266|Ensembl:ENSMUSG00000040680 +73017 2900072G19Rik MGI:MGI:1920267 +73020 2900073C17Rik MGI:MGI:1920270 +73021 Panct1 MGI:MGI:1920271 +73024 Emc7 MGI:MGI:1920274|Ensembl:ENSMUSG00000055943|Vega:OTTMUSG00000014816 +73027 2900046L07Rik MGI:MGI:1920277 +73028 2900046F13Rik MGI:MGI:1920278 +73031 2900060N12Rik MGI:MGI:1920281 +73032 Ttc9b MGI:MGI:1920282|Ensembl:ENSMUSG00000007944|Vega:OTTMUSG00000023957 +73033 2900072N19Rik MGI:MGI:1920283 +73034 2900064B16Rik MGI:MGI:1920284 +73035 2900073N21Rik MGI:MGI:1920285 +73040 2900052N01Rik MGI:MGI:1920290|Ensembl:ENSMUSG00000099696 +73041 2900060K15Rik MGI:MGI:1920291 +73043 2900064F13Rik MGI:MGI:1920293 +73046 Glrx5 MGI:MGI:1920296|Ensembl:ENSMUSG00000021102 +73047 Camk2n2 MGI:MGI:1920297|Ensembl:ENSMUSG00000051146|Vega:OTTMUSG00000028771 +73049 2900054C01Rik MGI:MGI:1920299 +73050 2900056L01Rik MGI:MGI:1920300 +73052 2900076G11Rik MGI:MGI:1920302 +73056 2900080J11Rik MGI:MGI:1920306 +73057 2900086E13Rik MGI:MGI:1920307 +73061 Cldn34c1 MGI:MGI:1920311|Ensembl:ENSMUSG00000079450|Vega:OTTMUSG00000018582 +73062 Ppp1r16a MGI:MGI:1920312|Ensembl:ENSMUSG00000033819|Vega:OTTMUSG00000032740 +73064 2900080M03Rik MGI:MGI:1920314 +73065 2900092O11Rik MGI:MGI:1920315 +73067 Tmem192 MGI:MGI:1920317|Ensembl:ENSMUSG00000025521|Vega:OTTMUSG00000061254 +73068 Fut11 MGI:MGI:1920318|Ensembl:ENSMUSG00000039357 +73072 Prr36 MGI:MGI:3605626|Ensembl:ENSMUSG00000064125|Vega:OTTMUSG00000041989 +73074 2900086B20Rik MGI:MGI:1920324 +73075 Ppil6 MGI:MGI:1920325|Ensembl:ENSMUSG00000078451|Vega:OTTMUSG00000063446 +73076 3100003L05Rik MGI:MGI:1920326|Ensembl:ENSMUSG00000086254 +73078 Pmpcb MGI:MGI:1920328|Ensembl:ENSMUSG00000029017|Vega:OTTMUSG00000025637 +73079 3110009M11Rik MGI:MGI:1920329 +73080 2900084O13Rik MGI:MGI:1920330 +73081 2900084C01Rik MGI:MGI:1920331 +73082 3100003M19Rik MGI:MGI:1920332 +73083 2900082C11Rik MGI:MGI:1920333 +73086 Rps6ka5 MGI:MGI:1920336|Ensembl:ENSMUSG00000021180 +73087 2900084I15Rik MGI:MGI:1920337 +73088 2900087K15Rik MGI:MGI:1920338 +73090 2900092C05Rik MGI:MGI:1920340|Ensembl:ENSMUSG00000030385|Vega:OTTMUSG00000027124 +73091 3110005L24Rik MGI:MGI:1920341 +73093 3110006O06Rik MGI:MGI:1920343 +73094 Sgip1 MGI:MGI:1920344|Ensembl:ENSMUSG00000028524|Vega:OTTMUSG00000008057 +73095 Slc25a42 MGI:MGI:1920345|Ensembl:ENSMUSG00000002346|Vega:OTTMUSG00000022210 +73096 2900092N11Rik MGI:MGI:1920346 +73098 3110005M07Rik MGI:MGI:1920348 +73099 3100003L13Rik MGI:MGI:1920349 +73100 2900092D14Rik MGI:MGI:1920350 +73102 Slc22a23 MGI:MGI:1920352|Ensembl:ENSMUSG00000038267|Vega:OTTMUSG00000033842 +73103 3110009E18Rik MGI:MGI:1920353|Ensembl:ENSMUSG00000026388|Vega:OTTMUSG00000030546 +73104 3110005L21Rik MGI:MGI:1920354 +73106 Prss57 MGI:MGI:1920356|Ensembl:ENSMUSG00000020323|Vega:OTTMUSG00000035141 +73107 2900092N22Rik MGI:MGI:1920357 +73112 Abracl MGI:MGI:1920362|Ensembl:ENSMUSG00000078453 +73121 Rflna MGI:MGI:1920371|Ensembl:ENSMUSG00000037962|Vega:OTTMUSG00000026841 +73122 Tgfbrap1 MGI:MGI:2447427|Ensembl:ENSMUSG00000070939|Vega:OTTMUSG00000046304 +73123 3110013M02Rik MGI:MGI:1920373 +73124 Golim4 MGI:MGI:1920374|Ensembl:ENSMUSG00000034109|Vega:OTTMUSG00000029722 +73125 3110037C07Rik MGI:MGI:1920375 +73126 3110038A09Rik MGI:MGI:1920376 +73127 3110039C02Rik MGI:MGI:1920377 +73129 3110015C05Rik MGI:MGI:1920379 +73130 Tmed5 MGI:MGI:1921586|Ensembl:ENSMUSG00000063406|Vega:OTTMUSG00000028919 +73132 Slc25a16 MGI:MGI:1920382|Ensembl:ENSMUSG00000071253|Vega:OTTMUSG00000030805 +73134 3110023J12Rik MGI:MGI:1920384 +73137 Prrc1 MGI:MGI:1916106|Ensembl:ENSMUSG00000024594 +73139 Cenpv MGI:MGI:1920389|Ensembl:ENSMUSG00000018509|Vega:OTTMUSG00000005860 +73140 3110040K02Rik MGI:MGI:1920390 +73141 3110031N09Rik MGI:MGI:1920391 +73142 3110035F07Rik MGI:MGI:1920392 +73144 3110039I08Rik MGI:MGI:1920394|Ensembl:ENSMUSG00000074415 +73145 3110037L02Rik MGI:MGI:1920395 +73149 Clec4a3 MGI:MGI:1920399|Ensembl:ENSMUSG00000043832|Vega:OTTMUSG00000027032 +73154 3110018A10Rik MGI:MGI:1920404 +73158 Larp1 MGI:MGI:1890165|Ensembl:ENSMUSG00000037331|Vega:OTTMUSG00000005720 +73160 3110018I06Rik MGI:MGI:1920410 +73161 3110035C09Rik MGI:MGI:1920411 +73162 Otud3 MGI:MGI:1920412|Ensembl:ENSMUSG00000041161|Vega:OTTMUSG00000009799 +73164 3110037B15Rik MGI:MGI:1920414 +73166 Tm7sf2 MGI:MGI:1920416|Ensembl:ENSMUSG00000024799|Vega:OTTMUSG00000024785 +73167 Arhgap8 MGI:MGI:1920417|Ensembl:ENSMUSG00000078954|Vega:OTTMUSG00000035391 +73168 3110027N22Rik MGI:MGI:1920418 +73169 3110035G12Rik MGI:MGI:1920419 +73172 Exo5 MGI:MGI:1920422|Ensembl:ENSMUSG00000028629|Vega:OTTMUSG00000008855 +73173 Pcdh18 MGI:MGI:1920423|Ensembl:ENSMUSG00000037892|Vega:OTTMUSG00000051508 +73174 Tbkbp1 MGI:MGI:1920424|Ensembl:ENSMUSG00000038517|Vega:OTTMUSG00000002304 +73176 3110040M04Rik MGI:MGI:1920426 +73178 Wasl MGI:MGI:1920428|Ensembl:ENSMUSG00000029684|Vega:OTTMUSG00000037666 +73181 Nfatc4 MGI:MGI:1920431|Ensembl:ENSMUSG00000023411 +73182 Pear1 MGI:MGI:1920432|Ensembl:ENSMUSG00000028073|Vega:OTTMUSG00000036958 +73183 5430402O13Rik MGI:MGI:1918631|Ensembl:ENSMUSG00000085776 +73184 3110047M12Rik MGI:MGI:1920434 +73186 3110045A19Rik MGI:MGI:1920436 +73187 3110067G11Rik MGI:MGI:1920437 +73188 3110062G12Rik MGI:MGI:1920438 +73191 Fezf1 MGI:MGI:1920441|Ensembl:ENSMUSG00000029697|Vega:OTTMUSG00000055954 +73192 Xpot MGI:MGI:1920442|Ensembl:ENSMUSG00000034667 +73193 3110043J17Rik MGI:MGI:1920443 +73197 3110056J03Rik MGI:MGI:1920447 +73201 3110073H01Rik MGI:MGI:1920451 +73204 3110056K07Rik MGI:MGI:1920454|Ensembl:ENSMUSG00000085622 +73205 3110043O21Rik MGI:MGI:1920455|Ensembl:ENSMUSG00000028300|Vega:OTTMUSG00000006496 +73207 3110068a07rik - +73208 3110083C13Rik MGI:MGI:1920458|Ensembl:ENSMUSG00000097303 +73212 3110082I17Rik MGI:MGI:1920462|Ensembl:ENSMUSG00000053553|Vega:OTTMUSG00000035852 +73216 B9d1os MGI:MGI:1920466|Ensembl:ENSMUSG00000060808 +73218 Sppl2b MGI:MGI:1920468|Ensembl:ENSMUSG00000035206 +73219 3110080E11Rik MGI:MGI:1920469 +73223 3110076C19Rik MGI:MGI:1920473 +73225 Fam118a MGI:MGI:1920475|Ensembl:ENSMUSG00000022434 +73229 Zfp983 MGI:MGI:1920479|Ensembl:ENSMUSG00000035868 +73230 Bmper MGI:MGI:1920480|Ensembl:ENSMUSG00000031963|Vega:OTTMUSG00000062429 +73233 Zfp942 MGI:MGI:1920483|Ensembl:ENSMUSG00000071267|Vega:OTTMUSG00000033054 +73234 3110079O15Rik MGI:MGI:1920484|Ensembl:ENSMUSG00000026258|Vega:OTTMUSG00000048194 +73238 3110049I03Rik MGI:MGI:1920488 +73239 3110054G05Rik MGI:MGI:1920489 +73240 3110056K14Rik MGI:MGI:1920490 +73241 3110080O07Rik MGI:MGI:1920491 +73242 Atat1 MGI:MGI:1913869|Ensembl:ENSMUSG00000024426|Vega:OTTMUSG00000033103 +73244 Prl8a1 MGI:MGI:1920494|Ensembl:ENSMUSG00000019756|Vega:OTTMUSG00000000645 +73246 Rassf6 MGI:MGI:1920496|Ensembl:ENSMUSG00000029370|Vega:OTTMUSG00000055490 +73247 Mrgbp MGI:MGI:1920497|Ensembl:ENSMUSG00000027569|Vega:OTTMUSG00000016332 +73248 1600015H23Rik MGI:MGI:1920498 +73249 1600017P15Rik MGI:MGI:1920499 +73250 Ceacam5 MGI:MGI:1920500|Ensembl:ENSMUSG00000008789|Vega:OTTMUSG00000058803 +73251 Setd7 MGI:MGI:1920501|Ensembl:ENSMUSG00000037111|Vega:OTTMUSG00000017099 +73252 1600022D10Rik MGI:MGI:1920502 +73254 Ccdc18 MGI:MGI:1922974|Ensembl:ENSMUSG00000056531|Vega:OTTMUSG00000053963 +73255 1700026J12Rik MGI:MGI:1920505|Ensembl:ENSMUSG00000073976 +73256 1700021G15Rik MGI:MGI:1920506 +73257 1700023C21Rik MGI:MGI:1920507|Ensembl:ENSMUSG00000087393 +73259 Cib4 MGI:MGI:1920509|Ensembl:ENSMUSG00000053194|Vega:OTTMUSG00000022278 +73260 1700041M05Rik MGI:MGI:1920510 +73261 1700037C18Rik MGI:MGI:1920511|Ensembl:ENSMUSG00000005983|Vega:OTTMUSG00000025498 +73262 1700036O09Rik MGI:MGI:1920512 +73264 1700037N05Rik MGI:MGI:1920514 +73265 1700038P13Rik MGI:MGI:1920515 +73266 Speer6-ps1 MGI:MGI:1920516|Ensembl:ENSMUSG00000091304 +73267 1700040K01Rik MGI:MGI:1920517 +73268 1700040P09Rik MGI:MGI:1920518 +73270 1700024F13Rik MGI:MGI:1920520|Ensembl:ENSMUSG00000097709 +73271 1700029K24Rik MGI:MGI:1920521 +73272 1700108F19Rik MGI:MGI:1920814|Ensembl:ENSMUSG00000101009 +73273 1700041I07Rik MGI:MGI:1920523 +73274 Gpbp1 MGI:MGI:1920524|Ensembl:ENSMUSG00000032745|Vega:OTTMUSG00000019752 +73276 1700037J18Rik MGI:MGI:1920526 +73278 1700031P21Rik MGI:MGI:1920528|Ensembl:ENSMUSG00000100315 +73279 1700023B13Rik MGI:MGI:1920529 +73280 1700028N14Rik MGI:MGI:1920530 +73281 1700023G09Rik MGI:MGI:1920531 +73282 1700034B16Rik MGI:MGI:1920532|Ensembl:ENSMUSG00000097302 +73283 1700036G14Rik MGI:MGI:1920533|Ensembl:ENSMUSG00000099995 +73284 Ddit4l MGI:MGI:1920534|Ensembl:ENSMUSG00000046818|Vega:OTTMUSG00000035296 +73285 1700037F24Rik MGI:MGI:1920535 +73286 1700031A10Rik MGI:MGI:1920536|Ensembl:ENSMUSG00000092239 +73287 1700040L02Rik MGI:MGI:1920537|Ensembl:ENSMUSG00000019945|Vega:OTTMUSG00000022968 +73288 Vps50 MGI:MGI:1920538|Ensembl:ENSMUSG00000001376|Vega:OTTMUSG00000035289 +73289 1700031C06Rik MGI:MGI:1920539 +73290 1700042O05Rik MGI:MGI:1920540 +73293 Ccdc103 MGI:MGI:1920543|Ensembl:ENSMUSG00000020930|Vega:OTTMUSG00000003082 +73294 1700040L08Rik MGI:MGI:1920544 +73295 1700047L14Rik MGI:MGI:1920545|Ensembl:ENSMUSG00000101762 +73296 Rhobtb3 MGI:MGI:1920546|Ensembl:ENSMUSG00000021589|Vega:OTTMUSG00000023271 +73297 1700034I23Rik MGI:MGI:1920547|Ensembl:ENSMUSG00000074619|Vega:OTTMUSG00000042556 +73299 1700041G16Rik MGI:MGI:1920549 +73300 1700031F05Rik MGI:MGI:1920550|Ensembl:ENSMUSG00000032894|Vega:OTTMUSG00000018180 +73301 Ttc29 MGI:MGI:1920551|Ensembl:ENSMUSG00000037101|Vega:OTTMUSG00000031442 +73302 1700031M16Rik MGI:MGI:1920552|Ensembl:ENSMUSG00000099353|Vega:OTTMUSG00000045206 +73303 Bcas1os2 MGI:MGI:1920553|Ensembl:ENSMUSG00000086999 +73304 1700034J04Rik MGI:MGI:1920554 +73305 1700038C09Rik MGI:MGI:1920555 +73306 1700044C05Rik MGI:MGI:1920556|Ensembl:ENSMUSG00000099911 +73307 1700046C09Rik MGI:MGI:1920557|Ensembl:ENSMUSG00000085561 +73309 Spanxn4 MGI:MGI:1920559 +73310 1700044K19Rik MGI:MGI:1920560 +73312 1700041A01Rik MGI:MGI:1920562 +73314 Lrrc69 MGI:MGI:1920564|Ensembl:ENSMUSG00000023151|Vega:OTTMUSG00000004550 +73315 1700041L08Rik MGI:MGI:1920565 +73316 Calr3 MGI:MGI:1920566|Ensembl:ENSMUSG00000019732|Vega:OTTMUSG00000031770 +73317 1700031F10Rik MGI:MGI:1920567 +73318 Ube2d2b MGI:MGI:1920568|Ensembl:ENSMUSG00000063447|Vega:OTTMUSG00000023561 +73321 1700042O10Rik MGI:MGI:1920571|Ensembl:ENSMUSG00000086391 +73322 1700039E22Rik MGI:MGI:1920572|Ensembl:ENSMUSG00000092369 +73323 1700047G07Rik MGI:MGI:1920573 +73324 Clhc1 MGI:MGI:1920574|Ensembl:ENSMUSG00000020461|Vega:OTTMUSG00000005332 +73326 4932702P03Rik MGI:MGI:1921673 +73327 Pradc1 MGI:MGI:1920577|Ensembl:ENSMUSG00000030008|Vega:OTTMUSG00000024137 +73329 1700040F15Rik MGI:MGI:1920579 +73330 1700018P08Rik MGI:MGI:1920580 +73331 1700034P13Rik MGI:MGI:1920581 +73332 Ccdc30 MGI:MGI:1920582|Ensembl:ENSMUSG00000028637|Vega:OTTMUSG00000009337 +73333 Slc25a31 MGI:MGI:1920583|Ensembl:ENSMUSG00000069041|Vega:OTTMUSG00000022633 +73334 1700040F17Rik MGI:MGI:1920584 +73335 1700047K16Rik MGI:MGI:1920585 +73336 Prss44 MGI:MGI:1920586|Ensembl:ENSMUSG00000032493|Vega:OTTMUSG00000033566 +73337 1700042D02Rik MGI:MGI:1920587 +73338 Itpripl1 MGI:MGI:1920588|Ensembl:ENSMUSG00000074825|Vega:OTTMUSG00000016018 +73339 1700047G03Rik MGI:MGI:1920589|Ensembl:ENSMUSG00000099349 +73340 Nptxr MGI:MGI:1920590|Ensembl:ENSMUSG00000022421|Vega:OTTMUSG00000034820 +73341 Arhgef6 MGI:MGI:1920591|Ensembl:ENSMUSG00000031133|Vega:OTTMUSG00000017820 +73344 1700034J05Rik MGI:MGI:1920594|Ensembl:ENSMUSG00000040163|Vega:OTTMUSG00000022992 +73346 1700039I01Rik MGI:MGI:1920596 +73347 Cldn34b2 MGI:MGI:1920597|Ensembl:ENSMUSG00000057402|Vega:OTTMUSG00000019346 +73348 1700045H11Rik MGI:MGI:1920598|Ensembl:ENSMUSG00000078492 +73349 1700042G15Rik MGI:MGI:1920599 +73350 1700045I11Rik MGI:MGI:1920600 +73352 1700051K13Rik MGI:MGI:1920602 +73353 Actrt2 MGI:MGI:1920603|Ensembl:ENSMUSG00000051276|Vega:OTTMUSG00000010447 +73355 1700048P04Rik MGI:MGI:1920605 +73356 1700054O05Rik MGI:MGI:1920606 +73357 1700048J15Rik MGI:MGI:1920607 +73358 1700054M17Rik MGI:MGI:1920608|Ensembl:ENSMUSG00000085889 +73359 1700055D16Rik MGI:MGI:1920609 +73360 Actrt1 MGI:MGI:1920610|Ensembl:ENSMUSG00000046615|Vega:OTTMUSG00000017582 +73361 1700061D13Rik MGI:MGI:1920611 +73363 1700056E22Rik MGI:MGI:1920613|Ensembl:ENSMUSG00000044854 +73364 1700063H06Rik MGI:MGI:1920614|Ensembl:ENSMUSG00000099266 +73365 1700049J03Rik MGI:MGI:1920615 +73366 1700051A21Rik MGI:MGI:1920616|Ensembl:ENSMUSG00000086951 +73367 1700052M09Rik MGI:MGI:1920617 +73368 Col20a1 MGI:MGI:1920618|Ensembl:ENSMUSG00000016356|Vega:OTTMUSG00000019845 +73371 1700052K07Rik MGI:MGI:1920621 +73373 Phospho2 MGI:MGI:1920623|Ensembl:ENSMUSG00000027088|Vega:OTTMUSG00000013032 +73374 1700055L01Rik MGI:MGI:1920624 +73375 1700057H21Rik MGI:MGI:1920625|Ensembl:ENSMUSG00000086007 +73376 Tex33 MGI:MGI:1920626|Ensembl:ENSMUSG00000062154 +73377 1700058P15Rik MGI:MGI:1920627 +73378 1700060L04Rik MGI:MGI:1920628 +73379 Dcbld2 MGI:MGI:1920629|Ensembl:ENSMUSG00000035107|Vega:OTTMUSG00000025632 +73381 Cmtm2a MGI:MGI:2447160|Ensembl:ENSMUSG00000074127|Vega:OTTMUSG00000034936 +73382 Prss52 MGI:MGI:1920632|Ensembl:ENSMUSG00000021966|Vega:OTTMUSG00000036315 +73385 Fam177a MGI:MGI:1920635|Ensembl:ENSMUSG00000095595 +73388 Bpifa3 MGI:MGI:1920638|Ensembl:ENSMUSG00000027482|Vega:OTTMUSG00000016855 +73389 Hbp1 MGI:MGI:894659|Ensembl:ENSMUSG00000002996|Vega:OTTMUSG00000040005 +73390 Msl3l2 MGI:MGI:1920640|Ensembl:ENSMUSG00000047669 +73391 1700060J05Rik MGI:MGI:1920641 +73392 1700056N10Rik MGI:MGI:1920642 +73393 1700056I18Rik MGI:MGI:1920643 +73395 1700049E22Rik MGI:MGI:1920645|Ensembl:ENSMUSG00000101553 +73396 1700048F04Rik MGI:MGI:1920646|Ensembl:ENSMUSG00000105274 +73397 1700055C04Rik MGI:MGI:1920647|Ensembl:ENSMUSG00000093616 +73398 Nipsnap3a MGI:MGI:1920648|Ensembl:ENSMUSG00000015242|Vega:OTTMUSG00000007155 +73399 1700060C20Rik MGI:MGI:1920649|Ensembl:ENSMUSG00000078957 +73400 1700064J06Rik MGI:MGI:1920650|Ensembl:ENSMUSG00000100681 +73405 1700055D18Rik MGI:MGI:1920655 +73406 1700067A10Rik MGI:MGI:1920656 +73407 Tepp MGI:MGI:1920657|Ensembl:ENSMUSG00000090206|Vega:OTTMUSG00000027372 +73408 1700065L07Rik MGI:MGI:1920658|Ensembl:ENSMUSG00000107408 +73409 1700065J11Rik MGI:MGI:1920659|Ensembl:ENSMUSG00000107341 +73410 1700065D16Rik MGI:MGI:1920660|Ensembl:ENSMUSG00000096655 +73412 Nme8 MGI:MGI:1920662|Ensembl:ENSMUSG00000041138|Vega:OTTMUSG00000024181 +73414 1700061A03Rik MGI:MGI:1920664 +73415 Gm9732 MGI:MGI:3796514 +73416 1700061D14Rik MGI:MGI:1920666 +73418 1700047O18Rik MGI:MGI:1920668 +73419 Armt1 MGI:MGI:1920669|Ensembl:ENSMUSG00000061759|Vega:OTTMUSG00000030945 +73420 Ccsap MGI:MGI:1920670|Ensembl:ENSMUSG00000031971|Vega:OTTMUSG00000031069 +73421 Cntrobos MGI:MGI:1920671 +73422 Prox2 MGI:MGI:1920672|Ensembl:ENSMUSG00000042320|Vega:OTTMUSG00000040164 +73423 1700058M13Rik MGI:MGI:1920673 +73424 1700064H15Rik MGI:MGI:1920674 +73425 1700060C16Rik MGI:MGI:1920675|Ensembl:ENSMUSG00000086887 +73426 1700066B17Rik MGI:MGI:1920676|Ensembl:ENSMUSG00000101634 +73428 1700058M10Rik MGI:MGI:1920678 +73429 Hoxd3os1 MGI:MGI:1923875 +73430 Zfp974 MGI:MGI:1920680|Ensembl:ENSMUSG00000070709|Vega:OTTMUSG00000027201 +73431 1700052K11Rik MGI:MGI:1920681 +73432 1700061N14Rik MGI:MGI:1920682 +73433 1700048O14Rik MGI:MGI:1920683 +73435 Tex35 MGI:MGI:1920685|Ensembl:ENSMUSG00000026592|Vega:OTTMUSG00000029783 +73437 1700064F23Rik MGI:MGI:1920687 +73438 1700061F12Rik MGI:MGI:1920688|Ensembl:ENSMUSG00000085580 +73440 1700062C10Rik MGI:MGI:1920690 +73441 1700057D03Rik MGI:MGI:1920691 +73442 Hspa12a MGI:MGI:1920692|Ensembl:ENSMUSG00000025092 +73445 1700048C15Rik MGI:MGI:1920695 +73447 Wdr13 MGI:MGI:1914661|Ensembl:ENSMUSG00000031166|Vega:OTTMUSG00000018090 +73449 1700066B19Rik MGI:MGI:1920699|Ensembl:ENSMUSG00000073598|Vega:OTTMUSG00000033149 +73450 1700063J08Rik MGI:MGI:1920700 +73451 Zfp763 MGI:MGI:1920701|Ensembl:ENSMUSG00000067430|Vega:OTTMUSG00000031523 +73452 1700063O14Rik MGI:MGI:1920702|Ensembl:ENSMUSG00000101978 +73453 1700067K01Rik MGI:MGI:1920703|Ensembl:ENSMUSG00000046408|Vega:OTTMUSG00000028911 +73454 1700063A18Rik MGI:MGI:1920704|Ensembl:ENSMUSG00000100062 +73455 1700065J18Rik MGI:MGI:1920705 +73456 Izumo1 MGI:MGI:1920706|Ensembl:ENSMUSG00000064158|Vega:OTTMUSG00000029510 +73457 1700064M15Rik MGI:MGI:1920707|Ensembl:ENSMUSG00000100211 +73458 Aldh3b3 MGI:MGI:1920708|Ensembl:ENSMUSG00000037263|Vega:OTTMUSG00000045246 +73461 1700061H18Rik MGI:MGI:1920711 +73462 1700052H01Rik MGI:MGI:1920712 +73463 Als2cr11 MGI:MGI:1920713|Ensembl:ENSMUSG00000072295|Vega:OTTMUSG00000023125 +73464 1700057A11Rik MGI:MGI:1920714 +73465 1700048B10Rik MGI:MGI:1920715 +73466 Ms4a13 MGI:MGI:1920716|Ensembl:ENSMUSG00000057240|Vega:OTTMUSG00000047039 +73467 1700066M21Rik MGI:MGI:1920717|Ensembl:ENSMUSG00000038323|Vega:OTTMUSG00000047047 +73469 Rnf38 MGI:MGI:1920719|Ensembl:ENSMUSG00000035696|Vega:OTTMUSG00000006919 +73470 Kif2b MGI:MGI:1920720|Ensembl:ENSMUSG00000046755|Vega:OTTMUSG00000001323 +73471 1700066N21Rik MGI:MGI:1920721|Ensembl:ENSMUSG00000099605 +73472 Spata18 MGI:MGI:1920722|Ensembl:ENSMUSG00000029155|Vega:OTTMUSG00000055948 +73473 Iws1 MGI:MGI:1920723|Ensembl:ENSMUSG00000024384|Vega:OTTMUSG00000061967 +73474 Snhg9 MGI:MGI:1920724|Ensembl:ENSMUSG00000090101 +73475 1700067G17Rik MGI:MGI:1920725|Ensembl:ENSMUSG00000099378 +73477 1700081H04Rik MGI:MGI:1920727|Ensembl:ENSMUSG00000100573 +73479 1700082C01Rik MGI:MGI:1920729 +73480 1700074H08Rik MGI:MGI:1920730|Ensembl:ENSMUSG00000099872 +73481 1700074P13Rik MGI:MGI:1920731|Ensembl:ENSMUSG00000029883|Vega:OTTMUSG00000026900 +73482 1700074A21Rik MGI:MGI:1920732 +73483 1700074A11Rik MGI:MGI:1920733 +73485 1700071G01Rik MGI:MGI:1920735 +73486 1700084J12Rik MGI:MGI:1920736|Ensembl:ENSMUSG00000058101 +73487 1700084M14Rik MGI:MGI:1920737|Ensembl:ENSMUSG00000057805|Vega:OTTMUSG00000017977 +73488 1700080G11Rik MGI:MGI:1920738 +73489 1700080N15Rik MGI:MGI:1920739|Ensembl:ENSMUSG00000084859 +73490 Mipol1 MGI:MGI:1920740|Ensembl:ENSMUSG00000047022|Vega:OTTMUSG00000032624 +73491 1700085D07Rik MGI:MGI:1920741 +73492 1700085G17Rik MGI:MGI:1920742 +73493 1700072H12Rik MGI:MGI:1920743 +73495 Samt3 MGI:MGI:1920745|Ensembl:ENSMUSG00000035454|Vega:OTTMUSG00000017947 +73496 1700072G22Rik MGI:MGI:1920746 +73498 1700084P21Rik MGI:MGI:1920748 +73500 1700081B01Rik MGI:MGI:1920750 +73503 Mbd3l1 MGI:MGI:1920753|Ensembl:ENSMUSG00000038691|Vega:OTTMUSG00000062585 +73504 1700071M16Rik MGI:MGI:1920754|Ensembl:ENSMUSG00000090307 +73505 1700072O05Rik MGI:MGI:1920755 +73510 1700082O11Rik MGI:MGI:1920760 +73512 1700085D22Rik MGI:MGI:1920762 +73515 Nell1os MGI:MGI:1920765|Ensembl:ENSMUSG00000085265 +73516 1700086O06Rik MGI:MGI:1920766|Ensembl:ENSMUSG00000097080 +73517 1700074L02Rik MGI:MGI:1920767 +73522 1700084M22Rik MGI:MGI:1920772 +73523 Pebp4 MGI:MGI:1920773|Ensembl:ENSMUSG00000022085 +73526 Speer4b MGI:MGI:1920776|Ensembl:ENSMUSG00000048703|Vega:OTTMUSG00000026698 +73528 1700081N11Rik MGI:MGI:1920778 +73529 1700072B07Rik MGI:MGI:1920779|Ensembl:ENSMUSG00000100487 +73530 1700074I03Rik MGI:MGI:1920780 +73531 1700069P05Rik MGI:MGI:1920781|Ensembl:ENSMUSG00000107637 +73532 1700080E11Rik MGI:MGI:1920782|Ensembl:ENSMUSG00000032566|Vega:OTTMUSG00000045307 +73533 1700080G18Rik MGI:MGI:1920783 +73534 1700082M22Rik MGI:MGI:1920784 +73536 1700092K14Rik MGI:MGI:1920786|Ensembl:ENSMUSG00000078600 +73538 1700105F02Rik MGI:MGI:1920788 +73540 1700100M05Rik MGI:MGI:1920790 +73542 Tssk5 MGI:MGI:1920792|Ensembl:ENSMUSG00000060794 +73544 1700093A15Rik MGI:MGI:1920794 +73545 1700094D03Rik MGI:MGI:1920795|Ensembl:ENSMUSG00000027942 +73547 Dusp21 MGI:MGI:1920797|Ensembl:ENSMUSG00000025043|Vega:OTTMUSG00000016962 +73548 1700094I16Rik MGI:MGI:1920798 +73549 1700110I01Rik MGI:MGI:1920799|Ensembl:ENSMUSG00000079407 +73550 1700105G05Rik MGI:MGI:1920800 +73551 1700101O05Rik MGI:MGI:1920801 +73552 1700091J24Rik MGI:MGI:1920802 +73553 1700091H14Rik MGI:MGI:1920803|Ensembl:ENSMUSG00000090462 +73554 1700092C10Rik MGI:MGI:1920804|Ensembl:ENSMUSG00000092499 +73557 1700096P03Rik MGI:MGI:1920807 +73558 1700110K17Rik MGI:MGI:1920808 +73559 1700106O07Rik MGI:MGI:1920809 +73560 1700108N06Rik MGI:MGI:1920810 +73561 1700097M23Rik MGI:MGI:1920811 +73563 1700095J12Rik MGI:MGI:1920813|Ensembl:ENSMUSG00000084804 +73567 Gldnos MGI:MGI:1920817|Ensembl:ENSMUSG00000074343 +73569 Vgll3 MGI:MGI:1920819|Ensembl:ENSMUSG00000091243 +73571 1700096K18Rik MGI:MGI:1920821|Ensembl:ENSMUSG00000101856 +73574 1700095J07Rik MGI:MGI:1920824 +73575 1700101O22Rik MGI:MGI:1920825|Ensembl:ENSMUSG00000102096 +73576 1700092E19Rik MGI:MGI:1920826 +73577 1700102F20Rik MGI:MGI:1920827 +73579 1700094M23Rik MGI:MGI:1920829 +73582 Camkmt MGI:MGI:1920832|Ensembl:ENSMUSG00000071037 +73583 1700112M02Rik MGI:MGI:1920833 +73584 1700100L14Rik MGI:MGI:1920834|Ensembl:ENSMUSG00000101051 +73585 1700111E14Rik MGI:MGI:1920835 +73586 1700101C01Rik MGI:MGI:1920836 +73588 St8sia3os MGI:MGI:1920838|Ensembl:ENSMUSG00000086128 +73589 1700101I19Rik MGI:MGI:1920839 +73590 1700112H15Rik MGI:MGI:1920840|Ensembl:ENSMUSG00000101574 +73591 1700109I08Rik MGI:MGI:1920841|Ensembl:ENSMUSG00000101261 +73592 1700104L18Rik MGI:MGI:1920842|Ensembl:ENSMUSG00000112821 +73593 1700112N08Rik MGI:MGI:1920843 +73594 1700112L15Rik MGI:MGI:1920844 +73596 1700112K13Rik MGI:MGI:1920846 +73597 1700113H21Rik MGI:MGI:1920847 +73598 1700001O22Rik MGI:MGI:1923631|Ensembl:ENSMUSG00000044320|Vega:OTTMUSG00000011876 +73599 1700120G11Rik MGI:MGI:1920849 +73600 1700120C14Rik MGI:MGI:1920850|Ensembl:ENSMUSG00000100599 +73602 1700126A01Rik MGI:MGI:1920852 +73603 Trp53tg5 MGI:MGI:1920853|Ensembl:ENSMUSG00000017720|Vega:OTTMUSG00000001090 +73605 1700124M09Rik MGI:MGI:1920855 +73606 1700120E14Rik MGI:MGI:1920856 +73608 Marveld3 MGI:MGI:1920858|Ensembl:ENSMUSG00000001672|Vega:OTTMUSG00000027477 +73609 1700125H03Rik MGI:MGI:1920859|Ensembl:ENSMUSG00000085197 +73610 Zfp433 MGI:MGI:1920860|Ensembl:ENSMUSG00000096795|Vega:OTTMUSG00000056317 +73611 1700112D23Rik MGI:MGI:1920861 +73612 1700127G19Rik MGI:MGI:1920862 +73614 Rhox13 MGI:MGI:1920864|Ensembl:ENSMUSG00000050197|Vega:OTTMUSG00000017201 +73615 1700128I11Rik MGI:MGI:1920865 +73616 Pldi MGI:MGI:1920866|Ensembl:ENSMUSG00000037247 +73617 1700122H20Rik MGI:MGI:1920867|Ensembl:ENSMUSG00000099735 +73618 1700128E19Rik MGI:MGI:1920868 +73619 1700122E12Rik MGI:MGI:1920869 +73622 1700116H05Rik MGI:MGI:1920872 +73624 1700123O12Rik MGI:MGI:1920874|Ensembl:ENSMUSG00000086080 +73626 1810009J06Rik MGI:MGI:1920876|Ensembl:ENSMUSG00000094808|Vega:OTTMUSG00000051311 +73628 1700125G02Rik MGI:MGI:1920878|Ensembl:ENSMUSG00000085263 +73629 1700123E06Rik MGI:MGI:1920879 +73631 1700128A07Rik MGI:MGI:1920881|Ensembl:ENSMUSG00000099794 +73633 1700121I08Rik MGI:MGI:1920883 +73634 1700125H20Rik MGI:MGI:1920884|Ensembl:ENSMUSG00000018479|Vega:OTTMUSG00000001030 +73635 Ptges3l MGI:MGI:1916146|Ensembl:ENSMUSG00000097487|Vega:OTTMUSG00000042663 +73636 1700125C05Rik MGI:MGI:1920886 +73639 1700126H18Rik MGI:MGI:1920889|Ensembl:ENSMUSG00000107014 +73640 1700113B19Rik MGI:MGI:1920890 +73641 1700125M20Rik MGI:MGI:1920891 +73644 2210039B01Rik MGI:MGI:1920894|Ensembl:ENSMUSG00000113800 +73647 Capn9 MGI:MGI:1920897|Ensembl:ENSMUSG00000031981|Vega:OTTMUSG00000029745 +73648 2410012E07Rik MGI:MGI:1920898|Ensembl:ENSMUSG00000099528 +73649 Cybrd1 MGI:MGI:2654575|Ensembl:ENSMUSG00000027015|Vega:OTTMUSG00000013155 +73650 2410024F20Rik MGI:MGI:1920900 +73652 2210408F21Rik MGI:MGI:1920902|Ensembl:ENSMUSG00000087380 +73656 Ms4a6c MGI:MGI:2385644|Ensembl:ENSMUSG00000079419|Vega:OTTMUSG00000047127 +73658 Spns1 MGI:MGI:1920908|Ensembl:ENSMUSG00000030741|Vega:OTTMUSG00000031445 +73660 Cabp4 MGI:MGI:1920910|Ensembl:ENSMUSG00000024842 +73661 2210419D22Rik MGI:MGI:1920911 +73665 2210037E17Rik MGI:MGI:1920915 +73666 Thoc3 MGI:MGI:1920916|Ensembl:ENSMUSG00000025872|Vega:OTTMUSG00000027733 +73667 2410004P03Rik MGI:MGI:1920917|Ensembl:ENSMUSG00000071398|Vega:OTTMUSG00000046346 +73668 Ttc21b MGI:MGI:1920918|Ensembl:ENSMUSG00000034848|Vega:OTTMUSG00000012999 +73670 Defb30 MGI:MGI:1920920|Ensembl:ENSMUSG00000075571|Vega:OTTMUSG00000020961 +73671 Sult6b1 MGI:MGI:1920921|Ensembl:ENSMUSG00000038045|Vega:OTTMUSG00000033017 +73673 Rec114 MGI:MGI:1920923|Ensembl:ENSMUSG00000074269|Vega:OTTMUSG00000042065 +73674 Wdr75 MGI:MGI:1920924|Ensembl:ENSMUSG00000025995|Vega:OTTMUSG00000022347 +73677 Psma8 MGI:MGI:1920927|Ensembl:ENSMUSG00000036743 +73679 Tex19.1 MGI:MGI:1920929|Ensembl:ENSMUSG00000039329|Vega:OTTMUSG00000004290 +73680 Zbtb8a MGI:MGI:1920930|Ensembl:ENSMUSG00000028807|Vega:OTTMUSG00000009664 +73681 Trmt11 MGI:MGI:1920931|Ensembl:ENSMUSG00000019792|Vega:OTTMUSG00000063787 +73683 Atg16l2 MGI:MGI:1920933|Ensembl:ENSMUSG00000047767|Vega:OTTMUSG00000031256 +73687 2410087M07Rik MGI:MGI:1920937 +73689 Bloc1s2 MGI:MGI:1920939|Ensembl:ENSMUSG00000057506 +73690 Glipr1 MGI:MGI:1920940|Ensembl:ENSMUSG00000056888|Vega:OTTMUSG00000027780 +73692 2410089E03Rik MGI:MGI:1920942|Ensembl:ENSMUSG00000039801|Vega:OTTMUSG00000022443 +73693 Dppa4 MGI:MGI:2157525|Ensembl:ENSMUSG00000058550 +73694 Ndufaf7 MGI:MGI:1920944|Ensembl:ENSMUSG00000024082 +73696 Platr9 MGI:MGI:1920946|Ensembl:ENSMUSG00000085824 +73699 Ppp2r1b MGI:MGI:1920949|Ensembl:ENSMUSG00000032058|Vega:OTTMUSG00000037681 +73703 Dppa2 MGI:MGI:2157523|Ensembl:ENSMUSG00000072419 +73707 Gucy2g MGI:MGI:106025|Ensembl:ENSMUSG00000055523|Vega:OTTMUSG00000033407 +73708 Dppa3 MGI:MGI:1920958|Ensembl:ENSMUSG00000046323|Vega:OTTMUSG00000024458 +73709 2410125D13Rik MGI:MGI:1920959 +73710 Tubb2b MGI:MGI:1920960|Ensembl:ENSMUSG00000045136 +73711 Mvb12a MGI:MGI:1920961|Ensembl:ENSMUSG00000031813|Vega:OTTMUSG00000062161 +73712 Dmkn MGI:MGI:1920962|Ensembl:ENSMUSG00000060962|Vega:OTTMUSG00000046054 +73713 Rbm20 MGI:MGI:1920963|Ensembl:ENSMUSG00000043639 +73719 Lce1c MGI:MGI:1920969|Ensembl:ENSMUSG00000042092|Vega:OTTMUSG00000051850 +73720 Cst6 MGI:MGI:1920970|Ensembl:ENSMUSG00000024846 +73721 1110017D15Rik MGI:MGI:1920971|Ensembl:ENSMUSG00000028441|Vega:OTTMUSG00000006656 +73722 Lce1a2 MGI:MGI:1920972|Ensembl:ENSMUSG00000068890|Vega:OTTMUSG00000051849 +73723 Sh3bgrl3 MGI:MGI:1920973|Ensembl:ENSMUSG00000028843|Vega:OTTMUSG00000010335 +73724 Mcee MGI:MGI:1920974|Ensembl:ENSMUSG00000033429|Vega:OTTMUSG00000027294 +73725 1110001D16Rik MGI:MGI:1920975 +73728 Psd MGI:MGI:1920978|Ensembl:ENSMUSG00000037126 +73729 Zfp383 MGI:MGI:1920979|Ensembl:ENSMUSG00000099689|Vega:OTTMUSG00000048224 +73730 Lce1l MGI:MGI:1920980|Ensembl:ENSMUSG00000046676|Vega:OTTMUSG00000051860 +73732 Muc16 MGI:MGI:1920982|Ensembl:ENSMUSG00000109564|Vega:OTTMUSG00000059301 +73736 Fcf1 MGI:MGI:1920986|Ensembl:ENSMUSG00000021243|Vega:OTTMUSG00000035484 +73737 1110008P14Rik MGI:MGI:1920987|Ensembl:ENSMUSG00000039195|Vega:OTTMUSG00000012952 +73738 Haus7 MGI:MGI:1920988|Ensembl:ENSMUSG00000031371|Vega:OTTMUSG00000017665 +73739 Cby1 MGI:MGI:1920989|Ensembl:ENSMUSG00000022428 +73744 Man2c1 MGI:MGI:1920994|Ensembl:ENSMUSG00000032295|Vega:OTTMUSG00000033295 +73747 1110034G24Rik MGI:MGI:1920997|Ensembl:ENSMUSG00000044991|Vega:OTTMUSG00000015666 +73748 Gadl1 MGI:MGI:1920998|Ensembl:ENSMUSG00000056880|Vega:OTTMUSG00000030875 +73750 Whrn MGI:MGI:2682003|Ensembl:ENSMUSG00000039137|Vega:OTTMUSG00000000249 +73754 Thap1 MGI:MGI:1921004|Ensembl:ENSMUSG00000037214|Vega:OTTMUSG00000031061 +73755 4833419A21Rik MGI:MGI:1921005 +73757 4833421G17Rik MGI:MGI:1921007 +73761 4833415N18Rik MGI:MGI:1921011 +73766 4833420D23Rik MGI:MGI:1921016 +73768 4833417J16Rik MGI:MGI:1921018 +73771 4930421P05Rik MGI:MGI:1921021 +73772 4930430J02Rik MGI:MGI:1921022 +73774 4930422M22Rik MGI:MGI:1921024 +73779 Prr27 MGI:MGI:1921029|Ensembl:ENSMUSG00000002240|Vega:OTTMUSG00000054074 +73781 4930432H08Rik MGI:MGI:1921031 +73782 4930421P22Rik MGI:MGI:1921032 +73783 4930422G07Rik MGI:MGI:1921033 +73784 4930430F21Rik MGI:MGI:1921034 +73785 4930431H11Rik MGI:MGI:1921035 +73786 4930429L21Rik MGI:MGI:1921036 +73787 4833406L22Rik MGI:MGI:1921037 +73788 4833408A19Rik MGI:MGI:1921038 +73790 4930401C12Rik MGI:MGI:1921040 +73791 4930404K06Rik MGI:MGI:1921041 +73792 4930401G09Rik MGI:MGI:1921042 +73793 4930405G09Rik MGI:MGI:1921043 +73794 4930402M22Rik MGI:MGI:1921044 +73795 4930405D01Rik MGI:MGI:1921045 +73796 4930402F11Rik MGI:MGI:1921046|Ensembl:ENSMUSG00000108885 +73797 4930405N21Rik MGI:MGI:1921047 +73798 4930402I19Rik MGI:MGI:1921048 +73802 4930401B06Rik MGI:MGI:1921052 +73803 4930401C15Rik MGI:MGI:1921053|Ensembl:ENSMUSG00000112444 +73804 Kif2c MGI:MGI:1921054|Ensembl:ENSMUSG00000028678|Vega:OTTMUSG00000009919 +73805 4930406D14Rik MGI:MGI:1921055 +73806 4930406D18Rik MGI:MGI:1921056|Ensembl:ENSMUSG00000086923 +73807 4930403P22Rik MGI:MGI:1921057 +73808 Tex36 MGI:MGI:1921058|Ensembl:ENSMUSG00000030976|Vega:OTTMUSG00000060673 +73809 Satl1 MGI:MGI:1921059|Ensembl:ENSMUSG00000025527 +73811 4930405J17Rik MGI:MGI:1921061|Ensembl:ENSMUSG00000110754 +73812 4930402C16Rik MGI:MGI:1921062 +73813 Fam83e MGI:MGI:1921063|Ensembl:ENSMUSG00000054161|Vega:OTTMUSG00000033719 +73814 4930403O15Rik MGI:MGI:1921064 +73815 4930404H11Rik MGI:MGI:1921065|Ensembl:ENSMUSG00000113630 +73816 4930401O10Rik MGI:MGI:1921066|Ensembl:ENSMUSG00000085528 +73817 4930404F17Rik MGI:MGI:1921067 +73818 4930405H06Rik MGI:MGI:1921068 +73819 4930402N20Rik MGI:MGI:1921069 +73820 4930404A05Rik MGI:MGI:1921070 +73821 4930401A07Rik MGI:MGI:1921071 +73822 Mfsd12 MGI:MGI:3604804|Ensembl:ENSMUSG00000034854|Vega:OTTMUSG00000030363 +73823 Gm17014 MGI:MGI:4452399 +73824 Snhg6 MGI:MGI:1921074|Ensembl:ENSMUSG00000098234 +73825 Ppp1r21 MGI:MGI:1921075|Ensembl:ENSMUSG00000034709|Vega:OTTMUSG00000048547 +73826 Poldip3 MGI:MGI:1921076|Ensembl:ENSMUSG00000041815|Vega:OTTMUSG00000032613 +73827 Tmem198b MGI:MGI:1921077|Ensembl:ENSMUSG00000047090|Vega:OTTMUSG00000033535 +73828 Dcaf4 MGI:MGI:1921078|Ensembl:ENSMUSG00000021222 +73830 Eif3k MGI:MGI:1921080|Ensembl:ENSMUSG00000053565|Vega:OTTMUSG00000059155 +73833 Fam98c MGI:MGI:1921083|Ensembl:ENSMUSG00000030590|Vega:OTTMUSG00000032908 +73834 Atp6v1d MGI:MGI:1921084|Ensembl:ENSMUSG00000021114 +73835 Ifitm5 MGI:MGI:1934923|Ensembl:ENSMUSG00000025489|Vega:OTTMUSG00000060379 +73836 Slc35b2 MGI:MGI:1921086|Ensembl:ENSMUSG00000037089 +73843 0610031I08Rik MGI:MGI:1921093 +73844 Ankrd45 MGI:MGI:1921094|Ensembl:ENSMUSG00000044835|Vega:OTTMUSG00000022133 +73845 Ankrd42 MGI:MGI:1921095|Ensembl:ENSMUSG00000041343|Vega:OTTMUSG00000029703 +73846 5430414B19Rik MGI:MGI:1921096 +73847 Fam110a MGI:MGI:1921097|Ensembl:ENSMUSG00000027459|Vega:OTTMUSG00000015830 +73848 5430406J06Rik MGI:MGI:1921098 +73851 4930415H17Rik MGI:MGI:1921101 +73852 D3Ertd751e MGI:MGI:1289213|Ensembl:ENSMUSG00000025766|Vega:OTTMUSG00000026520 +73854 4930428B01Rik MGI:MGI:1921104 +73855 4930429P21Rik MGI:MGI:1921105 +73856 4930428G15Rik MGI:MGI:1921106 +73857 4930429C20Rik MGI:MGI:1921107 +73859 4930414N08Rik - +73861 4930428B07Rik MGI:MGI:1921111 +73862 4930415F15Rik MGI:MGI:1921112|Ensembl:ENSMUSG00000020191|Vega:OTTMUSG00000025788 +73863 4930415O20Rik MGI:MGI:1921113|Ensembl:ENSMUSG00000022993 +73864 4930424E08Rik MGI:MGI:1921114 +73865 4930425K10Rik MGI:MGI:1921115|Ensembl:ENSMUSG00000106880 +73866 Fam122c MGI:MGI:1921116|Ensembl:ENSMUSG00000036013|Vega:OTTMUSG00000017352 +73867 4930428E07Rik MGI:MGI:1921117|Ensembl:ENSMUSG00000112967 +73868 4930415N12Rik MGI:MGI:1921118 +73869 4930414H07Rik MGI:MGI:1921119 +73870 4930417O13Rik MGI:MGI:1921120|Ensembl:ENSMUSG00000108129 +73871 4930428N03Rik MGI:MGI:1921121 +73872 4930423M02Rik MGI:MGI:1921122|Ensembl:ENSMUSG00000086066 +73873 Fam161a MGI:MGI:1921123|Ensembl:ENSMUSG00000049811|Vega:OTTMUSG00000005271 +73874 4930419G24Rik MGI:MGI:1921124|Ensembl:ENSMUSG00000087625 +73876 4930432F03Rik MGI:MGI:1921126 +73877 4930432J09Rik MGI:MGI:1921127 +73880 4930415C11Rik MGI:MGI:1921130 +73881 4930430M16Rik MGI:MGI:1921131 +73882 4930425P05Rik MGI:MGI:1921132 +73883 4930431P22Rik MGI:MGI:1921133 +73884 Zdbf2 MGI:MGI:1921134|Ensembl:ENSMUSG00000027520|Vega:OTTMUSG00000002659 +73886 4930431P19Rik MGI:MGI:1921136 +73887 4930417O22Rik MGI:MGI:1921137|Ensembl:ENSMUSG00000071818 +73889 4930413M19Rik MGI:MGI:1921139 +73891 4930423B08Rik MGI:MGI:1921141 +73892 4930423D24Rik MGI:MGI:1921142|Ensembl:ENSMUSG00000112753 +73893 Tmem202 MGI:MGI:1921143|Ensembl:ENSMUSG00000049526|Vega:OTTMUSG00000063294 +73894 4930414N06Rik MGI:MGI:1921144 +73895 4930431P03Rik MGI:MGI:1921145 +73897 4930429H19Rik MGI:MGI:1921147 +73898 4930429E23Rik MGI:MGI:1921148 +73899 LOC73899 - +73902 Psmb11 MGI:MGI:1921152|Ensembl:ENSMUSG00000072423 +73903 4833403J16Rik MGI:MGI:1921153 +73904 4833412C05Rik MGI:MGI:1921154|Ensembl:ENSMUSG00000097697 +73905 4833412E19Rik MGI:MGI:1921155 +73906 4833417C18Rik MGI:MGI:1921156|Ensembl:ENSMUSG00000086015 +73907 4833418N17Rik MGI:MGI:1921157 +73909 4833419O12Rik MGI:MGI:1921159 +73910 Arhgap18 MGI:MGI:1921160|Ensembl:ENSMUSG00000039031|Vega:OTTMUSG00000024292 +73911 4833413N01Rik MGI:MGI:1921161 +73914 Irak3 MGI:MGI:1921164|Ensembl:ENSMUSG00000020227|Vega:OTTMUSG00000034096 +73915 4833419F23Rik MGI:MGI:1921165 +73916 Ift57 MGI:MGI:1921166|Ensembl:ENSMUSG00000032965|Vega:OTTMUSG00000023119 +73918 4930404I20Rik MGI:MGI:1921168 +73919 Lyrm1 MGI:MGI:1921169|Ensembl:ENSMUSG00000030922|Vega:OTTMUSG00000025610 +73920 4930405A07Rik MGI:MGI:1921170 +73921 Scpep1os MGI:MGI:1921171|Ensembl:ENSMUSG00000087338 +73922 4930405D11Rik MGI:MGI:1921172|Ensembl:ENSMUSG00000085940 +73924 4930401O12Rik MGI:MGI:1921174|Ensembl:ENSMUSG00000087460 +73925 4930404O17Rik MGI:MGI:1921175 +73927 4930412F09Rik MGI:MGI:1921177 +73928 4930408O17Rik MGI:MGI:1921178 +73929 4930402C01Rik MGI:MGI:1921179 +73930 4930408K12Rik MGI:MGI:1921180 +73932 4930406M16Rik MGI:MGI:1921182 +73933 4930412O06Rik MGI:MGI:1921183 +73934 Cldn34c4 MGI:MGI:1921184|Ensembl:ENSMUSG00000043569|Vega:OTTMUSG00000018649 +73936 Ccdc175 MGI:MGI:1921186|Ensembl:ENSMUSG00000021086 +73937 1700029M20Rik MGI:MGI:1913597|Ensembl:ENSMUSG00000086788 +73938 4930412B13Rik MGI:MGI:1921188|Ensembl:ENSMUSG00000086221 +73940 Hapln2 MGI:MGI:2137300|Ensembl:ENSMUSG00000004894|Vega:OTTMUSG00000027207 +73941 4930412L05Rik MGI:MGI:1921191 +73942 Fam151b MGI:MGI:1921192|Ensembl:ENSMUSG00000034334 +73943 4930403O18Rik MGI:MGI:1921193 +73945 Otud4 MGI:MGI:1098801|Ensembl:ENSMUSG00000036990|Vega:OTTMUSG00000037239 +73946 4930423O20Rik MGI:MGI:1921196 +73948 4930415P13Rik MGI:MGI:1921198 +73949 Speer9-ps1 MGI:MGI:1921199|Ensembl:ENSMUSG00000107956 +73951 4930413G21Rik MGI:MGI:1921201 +73952 4930420N18Rik MGI:MGI:1921202 +73953 4930421J07Rik MGI:MGI:1921203 +73954 4930431L21Rik MGI:MGI:1921204 +73955 4930449I04Rik MGI:MGI:1921205 +73957 4930451G21Rik MGI:MGI:1921207 +73959 4930433B08Rik MGI:MGI:1921209|Ensembl:ENSMUSG00000102699 +73961 4930447J18Rik MGI:MGI:1921211 +73962 4930441J16Rik MGI:MGI:1921212|Ensembl:ENSMUSG00000085405 +73963 4930434F21Rik MGI:MGI:1921213 +73965 4930448I18Rik MGI:MGI:1921215|Ensembl:ENSMUSG00000104870 +73966 4930449I21Rik MGI:MGI:1921216 +73967 4930451A11Rik MGI:MGI:1921217 +73968 4930444F02Rik MGI:MGI:1921218 +73972 4930448C13Rik MGI:MGI:1921222|Ensembl:ENSMUSG00000113644 +73973 4930434B07Rik MGI:MGI:1921223 +73974 4930452L12Rik MGI:MGI:1921224 +73976 4930437M23Rik MGI:MGI:1921226|Ensembl:ENSMUSG00000105688 +73977 4930438E09Rik MGI:MGI:1921227|Ensembl:ENSMUSG00000093472 +73978 4930442B02Rik MGI:MGI:1921228 +73979 4930434J08Rik MGI:MGI:1921229 +73980 4930444A19Rik MGI:MGI:1921230 +73982 4930448E06Rik MGI:MGI:1921232 +73985 4930445N18Rik MGI:MGI:1921235|Ensembl:ENSMUSG00000097738 +73986 4930442G10Rik MGI:MGI:1921236 +73988 4930438A08Rik MGI:MGI:1921238|Ensembl:ENSMUSG00000069873|Vega:OTTMUSG00000005724 +73989 4930452G13Rik MGI:MGI:1921239 +73990 4930455C13Rik MGI:MGI:1921240|Ensembl:ENSMUSG00000112654 +73991 Atl1 MGI:MGI:1921241|Ensembl:ENSMUSG00000021066 +73992 4930448F12Rik MGI:MGI:1921242|Ensembl:ENSMUSG00000113470 +73993 4930448A20Rik MGI:MGI:1921243 +73994 4930449C09Rik MGI:MGI:1921244 +73998 Herc3 MGI:MGI:1921248|Ensembl:ENSMUSG00000029804|Vega:OTTMUSG00000017307 +74002 Psd2 MGI:MGI:1921252|Ensembl:ENSMUSG00000024347|Vega:OTTMUSG00000042038 +74004 Jakmip3 MGI:MGI:1921254 +74005 6330412A17Rik MGI:MGI:1921255 +74006 Dnm1l MGI:MGI:1921256|Ensembl:ENSMUSG00000022789 +74007 Btbd11 MGI:MGI:1921257|Ensembl:ENSMUSG00000020042|Vega:OTTMUSG00000017451 +74008 Arsg MGI:MGI:1921258|Ensembl:ENSMUSG00000020604|Vega:OTTMUSG00000003356 +74011 Slc25a27 MGI:MGI:1921261|Ensembl:ENSMUSG00000023912 +74012 Rap2b MGI:MGI:1921262|Ensembl:ENSMUSG00000036894|Vega:OTTMUSG00000051923 +74013 Rftn2 MGI:MGI:1921263|Ensembl:ENSMUSG00000025978|Vega:OTTMUSG00000021806 +74014 3732407C23Rik MGI:MGI:1921264 +74015 Fcho1 MGI:MGI:1921265|Ensembl:ENSMUSG00000070000|Vega:OTTMUSG00000034041 +74016 Phf19 MGI:MGI:1921266|Ensembl:ENSMUSG00000026873|Vega:OTTMUSG00000012270 +74018 Als2 MGI:MGI:1921268|Ensembl:ENSMUSG00000026024|Vega:OTTMUSG00000021752 +74019 Traf3ip1 MGI:MGI:1921269|Ensembl:ENSMUSG00000034292|Vega:OTTMUSG00000048497 +74020 Cpne4 MGI:MGI:1921270|Ensembl:ENSMUSG00000032564|Vega:OTTMUSG00000023466 +74021 3222402N08Rik MGI:MGI:1921271 +74022 Glyr1 MGI:MGI:1921272|Ensembl:ENSMUSG00000022536 +74023 Rd3 MGI:MGI:1921273|Ensembl:ENSMUSG00000049353|Vega:OTTMUSG00000042235 +74025 Nphp3 MGI:MGI:1921275|Ensembl:ENSMUSG00000032558|Vega:OTTMUSG00000031730 +74026 Msl1 MGI:MGI:1921276|Ensembl:ENSMUSG00000052915|Vega:OTTMUSG00000006405 +74030 Rin2 MGI:MGI:1921280|Ensembl:ENSMUSG00000001768|Vega:OTTMUSG00000004057 +74032 Sdr42e1 MGI:MGI:1921282|Ensembl:ENSMUSG00000034308|Vega:OTTMUSG00000038096 +74034 4632404H12Rik MGI:MGI:1921284|Ensembl:ENSMUSG00000042579 +74035 Nol9 MGI:MGI:1921285|Ensembl:ENSMUSG00000028948|Vega:OTTMUSG00000010374 +74036 4632409D06Rik MGI:MGI:1921286 +74038 Brip1os MGI:MGI:1921288|Ensembl:ENSMUSG00000085208 +74039 Nfam1 MGI:MGI:1921289|Ensembl:ENSMUSG00000058099|Vega:OTTMUSG00000014993 +74041 Ddias MGI:MGI:1921291|Ensembl:ENSMUSG00000030641|Vega:OTTMUSG00000059924 +74042 4921501E09Rik MGI:MGI:1921292|Ensembl:ENSMUSG00000023350 +74043 Pex26 MGI:MGI:1921293|Ensembl:ENSMUSG00000067825|Vega:OTTMUSG00000026945 +74044 Ttf2 MGI:MGI:1921294|Ensembl:ENSMUSG00000033222|Vega:OTTMUSG00000007085 +74045 Slc36a1os MGI:MGI:1921295|Ensembl:ENSMUSG00000084980 +74046 4632432E15Rik MGI:MGI:1921296 +74048 Vsir MGI:MGI:1921298|Ensembl:ENSMUSG00000020101|Vega:OTTMUSG00000016473 +74050 4921525O09Rik MGI:MGI:1921300|Ensembl:ENSMUSG00000113211 +74051 Steap2 MGI:MGI:1921301|Ensembl:ENSMUSG00000015653|Vega:OTTMUSG00000021588 +74052 Ttc21a MGI:MGI:1921302|Ensembl:ENSMUSG00000032514|Vega:OTTMUSG00000032843 +74053 Grip1 MGI:MGI:1921303|Ensembl:ENSMUSG00000034813|Vega:OTTMUSG00000033545 +74054 4931406B18Rik MGI:MGI:1921304|Ensembl:ENSMUSG00000013353|Vega:OTTMUSG00000036021 +74055 Plce1 MGI:MGI:1921305|Ensembl:ENSMUSG00000024998|Vega:OTTMUSG00000043393 +74056 4933402E15Rik MGI:MGI:1921306 +74057 4933405D12Rik MGI:MGI:1921307|Ensembl:ENSMUSG00000097852 +74059 4933406G16Rik MGI:MGI:1921309|Ensembl:ENSMUSG00000086025 +74061 4933404K08Rik MGI:MGI:1921311|Ensembl:ENSMUSG00000085122 +74062 Speer8-ps1 MGI:MGI:1921312 +74064 4933406J09Rik MGI:MGI:1921314 +74065 4933406D12Rik MGI:MGI:1921315|Ensembl:ENSMUSG00000085796 +74066 4933404G15Rik MGI:MGI:1921316 +74068 Asz1 MGI:MGI:1921318|Ensembl:ENSMUSG00000010796|Vega:OTTMUSG00000023407 +74069 Serpina3a MGI:MGI:1921319|Ensembl:ENSMUSG00000041536|Vega:OTTMUSG00000035420 +74071 Lmntd1 MGI:MGI:1921321|Ensembl:ENSMUSG00000054966|Vega:OTTMUSG00000022798 +74072 4933407I05Rik MGI:MGI:1921322|Ensembl:ENSMUSG00000111836 +74075 Syce1 MGI:MGI:1921325|Ensembl:ENSMUSG00000025480|Vega:OTTMUSG00000060434 +74076 4933406C10Rik MGI:MGI:1921326|Ensembl:ENSMUSG00000097494 +74077 4933411E02Rik MGI:MGI:1921327 +74078 4933412L11Rik MGI:MGI:1921328 +74080 Nmnat3 MGI:MGI:1921330|Ensembl:ENSMUSG00000032456|Vega:OTTMUSG00000022653 +74081 Cep350 MGI:MGI:1921331|Ensembl:ENSMUSG00000033671|Vega:OTTMUSG00000033963 +74083 4933411K05Rik MGI:MGI:1921333 +74084 4933408A14Rik MGI:MGI:1921334 +74085 4933414I06Rik MGI:MGI:1921335 +74086 4933411D12Rik MGI:MGI:1921336 +74087 Slc7a13 MGI:MGI:1921337|Ensembl:ENSMUSG00000041052|Vega:OTTMUSG00000006379 +74088 Them7 MGI:MGI:1921338|Ensembl:ENSMUSG00000055312|Vega:OTTMUSG00000014989 +74090 Paqr5 MGI:MGI:1921340|Ensembl:ENSMUSG00000032278|Vega:OTTMUSG00000023988 +74091 Npl MGI:MGI:1921341|Ensembl:ENSMUSG00000042684|Vega:OTTMUSG00000049716 +74092 Tbc1d22bos MGI:MGI:1921342|Ensembl:ENSMUSG00000089900 +74093 0610033M10Rik MGI:MGI:1921343 +74094 Tjap1 MGI:MGI:1921344|Ensembl:ENSMUSG00000012296 +74095 0610042E11Rik MGI:MGI:1921345 +74096 Hvcn1 MGI:MGI:1921346|Ensembl:ENSMUSG00000064267|Vega:OTTMUSG00000022575 +74097 Pop7 MGI:MGI:1921347|Ensembl:ENSMUSG00000029715|Vega:OTTMUSG00000021945 +74098 0610037L13Rik MGI:MGI:1921348|Ensembl:ENSMUSG00000028608|Vega:OTTMUSG00000009227 +74100 Arpp21 MGI:MGI:107562|Ensembl:ENSMUSG00000032503|Vega:OTTMUSG00000034741 +74102 Slc35a5 MGI:MGI:1921352|Ensembl:ENSMUSG00000022664|Vega:OTTMUSG00000024963 +74103 Nebl MGI:MGI:1921353|Ensembl:ENSMUSG00000053702|Vega:OTTMUSG00000011425 +74104 Abcb6 MGI:MGI:1921354|Ensembl:ENSMUSG00000026198|Vega:OTTMUSG00000034720 +74105 Gga2 MGI:MGI:1921355|Ensembl:ENSMUSG00000030872|Vega:OTTMUSG00000025491 +74106 Dcaf6 MGI:MGI:1921356|Ensembl:ENSMUSG00000026571|Vega:OTTMUSG00000037113 +74107 Cep55 MGI:MGI:1921357|Ensembl:ENSMUSG00000024989 +74108 Parn MGI:MGI:1921358|Ensembl:ENSMUSG00000022685 +74111 Rbm19 MGI:MGI:1921361|Ensembl:ENSMUSG00000029594|Vega:OTTMUSG00000056239 +74112 Usp16 MGI:MGI:1921362|Ensembl:ENSMUSG00000025616|Vega:OTTMUSG00000026485 +74114 Crot MGI:MGI:1921364|Ensembl:ENSMUSG00000003623|Vega:OTTMUSG00000024301 +74116 Pi16 MGI:MGI:1921366|Ensembl:ENSMUSG00000024011|Vega:OTTMUSG00000021155 +74117 Actr3 MGI:MGI:1921367|Ensembl:ENSMUSG00000026341|Vega:OTTMUSG00000049251 +74119 1200007C13Rik MGI:MGI:1921369 +74120 Zfp263 MGI:MGI:1921370|Ensembl:ENSMUSG00000022529|Vega:OTTMUSG00000035126 +74121 Acoxl MGI:MGI:1921371|Ensembl:ENSMUSG00000027380|Vega:OTTMUSG00000016096 +74122 Tmem43 MGI:MGI:1921372|Ensembl:ENSMUSG00000030095|Vega:OTTMUSG00000023824 +74123 Foxp4 MGI:MGI:1921373|Ensembl:ENSMUSG00000023991|Vega:OTTMUSG00000018348 +74125 Armc8 MGI:MGI:1921375|Ensembl:ENSMUSG00000032468|Vega:OTTMUSG00000048237 +74126 Syvn1 MGI:MGI:1921376|Ensembl:ENSMUSG00000024807|Vega:OTTMUSG00000032981 +74127 Krt80 MGI:MGI:1921377|Ensembl:ENSMUSG00000037185 +74129 Dmgdh MGI:MGI:1921379|Ensembl:ENSMUSG00000042102|Vega:OTTMUSG00000024424 +74131 Sash3 MGI:MGI:1921381|Ensembl:ENSMUSG00000031101|Vega:OTTMUSG00000017509 +74132 Rnf6 MGI:MGI:1921382|Ensembl:ENSMUSG00000029634|Vega:OTTMUSG00000031090 +74133 Smg8 MGI:MGI:1921383|Ensembl:ENSMUSG00000020495|Vega:OTTMUSG00000001221 +74134 Cyp2s1 MGI:MGI:1921384|Ensembl:ENSMUSG00000040703|Vega:OTTMUSG00000024365 +74136 Sec14l1 MGI:MGI:1921386|Ensembl:ENSMUSG00000020823|Vega:OTTMUSG00000003778 +74137 Nuak2 MGI:MGI:1921387|Ensembl:ENSMUSG00000009772|Vega:OTTMUSG00000021956 +74140 Tm9sf1 MGI:MGI:1921390|Ensembl:ENSMUSG00000002320|Vega:OTTMUSG00000027875 +74142 Lonp1 MGI:MGI:1921392|Ensembl:ENSMUSG00000041168 +74143 Opa1 MGI:MGI:1921393|Ensembl:ENSMUSG00000038084|Vega:OTTMUSG00000031484 +74144 Robo4 MGI:MGI:1921394|Ensembl:ENSMUSG00000032125|Vega:OTTMUSG00000016772 +74145 F13a1 MGI:MGI:1921395|Ensembl:ENSMUSG00000039109 +74147 Ehhadh MGI:MGI:1277964|Ensembl:ENSMUSG00000022853|Vega:OTTMUSG00000033863 +74148 Cluh MGI:MGI:1921398|Ensembl:ENSMUSG00000020741|Vega:OTTMUSG00000006183 +74149 Zfp946 MGI:MGI:1921399|Ensembl:ENSMUSG00000071266|Vega:OTTMUSG00000031362 +74150 Slc35f5 MGI:MGI:1921400|Ensembl:ENSMUSG00000026342|Vega:OTTMUSG00000049262 +74152 Stra6l MGI:MGI:1921402|Ensembl:ENSMUSG00000028327|Vega:OTTMUSG00000006732 +74153 Uba7 MGI:MGI:1349462|Ensembl:ENSMUSG00000032596|Vega:OTTMUSG00000042010 +74154 Unkl MGI:MGI:1921404|Ensembl:ENSMUSG00000015127|Vega:OTTMUSG00000035060 +74155 Errfi1 MGI:MGI:1921405|Ensembl:ENSMUSG00000028967|Vega:OTTMUSG00000010157 +74156 Acot12 MGI:MGI:1921406|Ensembl:ENSMUSG00000021620|Vega:OTTMUSG00000024121 +74157 Cmtr1 MGI:MGI:1921407|Ensembl:ENSMUSG00000024019|Vega:OTTMUSG00000033063 +74158 Josd1 MGI:MGI:1921408|Ensembl:ENSMUSG00000022426 +74159 Acbd5 MGI:MGI:1921409|Ensembl:ENSMUSG00000026781|Vega:OTTMUSG00000011559 +74160 1300014J16Rik MGI:MGI:1921410 +74161 Ctcflos MGI:MGI:1921411|Ensembl:ENSMUSG00000087382 +74164 Nfx1 MGI:MGI:1921414|Ensembl:ENSMUSG00000028423|Vega:OTTMUSG00000006622 +74165 Fbxl22 MGI:MGI:1921415|Ensembl:ENSMUSG00000050503 +74166 Tmem38a MGI:MGI:1921416|Ensembl:ENSMUSG00000031791|Vega:OTTMUSG00000062136 +74167 Nudt9 MGI:MGI:1921417|Ensembl:ENSMUSG00000029310|Vega:OTTMUSG00000022050 +74168 Zdhhc16 MGI:MGI:1921418|Ensembl:ENSMUSG00000025157 +74169 1810010K12Rik MGI:MGI:1921419 +74173 Rab10os MGI:MGI:1921423|Ensembl:ENSMUSG00000079179 +74174 Gtsf1 MGI:MGI:1921424|Ensembl:ENSMUSG00000022487|Vega:OTTMUSG00000034009 +74175 Crct1 MGI:MGI:1921425|Ensembl:ENSMUSG00000027913|Vega:OTTMUSG00000021866 +74176 Tgm5 MGI:MGI:1921426|Ensembl:ENSMUSG00000053675|Vega:OTTMUSG00000015969 +74177 2310007O11Rik MGI:MGI:1921427 +74178 Stk40 MGI:MGI:1921428|Ensembl:ENSMUSG00000042608|Vega:OTTMUSG00000009292 +74179 1700030A11Rik MGI:MGI:1921429|Ensembl:ENSMUSG00000085333 +74180 Muc5b MGI:MGI:1921430|Ensembl:ENSMUSG00000066108|Vega:OTTMUSG00000047461 +74181 2310024H09Rik MGI:MGI:1921431 +74182 Gpcpd1 MGI:MGI:104898|Ensembl:ENSMUSG00000027346|Vega:OTTMUSG00000015660 +74183 Perm1 MGI:MGI:1921433|Ensembl:ENSMUSG00000078486|Vega:OTTMUSG00000046104 +74184 2310065F04Rik MGI:MGI:1921434|Ensembl:ENSMUSG00000087410 +74185 Gbe1 MGI:MGI:1921435|Ensembl:ENSMUSG00000022707|Vega:OTTMUSG00000036833 +74186 Ccdc3 MGI:MGI:1921436|Ensembl:ENSMUSG00000026676|Vega:OTTMUSG00000010865 +74187 Katnb1 MGI:MGI:1921437|Ensembl:ENSMUSG00000031787|Vega:OTTMUSG00000061713 +74188 Prl8a8 MGI:MGI:1921438|Ensembl:ENSMUSG00000021346|Vega:OTTMUSG00000000644 +74189 Phactr3 MGI:MGI:1921439|Ensembl:ENSMUSG00000027525|Vega:OTTMUSG00000016326 +74190 Exoc3l4 MGI:MGI:1921363|Ensembl:ENSMUSG00000021280 +74191 P2ry13 MGI:MGI:1921441|Ensembl:ENSMUSG00000036362|Vega:OTTMUSG00000052358 +74192 Arpc5l MGI:MGI:1921442|Ensembl:ENSMUSG00000026755|Vega:OTTMUSG00000012418 +74194 Rnd3 MGI:MGI:1921444|Ensembl:ENSMUSG00000017144|Vega:OTTMUSG00000012429 +74195 Elp3 MGI:MGI:1921445|Ensembl:ENSMUSG00000022031 +74196 Ttc27 MGI:MGI:1921446|Ensembl:ENSMUSG00000024078 +74197 Gtf2e1 MGI:MGI:1921447|Ensembl:ENSMUSG00000022828|Vega:OTTMUSG00000025449 +74198 Dtx2 MGI:MGI:1921448|Ensembl:ENSMUSG00000004947|Vega:OTTMUSG00000025375 +74199 Vit MGI:MGI:1921449|Ensembl:ENSMUSG00000024076 +74200 2810403A07Rik MGI:MGI:1921450|Ensembl:ENSMUSG00000028060|Vega:OTTMUSG00000052464 +74201 Cep97 MGI:MGI:1921451|Ensembl:ENSMUSG00000022604|Vega:OTTMUSG00000030082 +74202 Fblim1 MGI:MGI:1921452|Ensembl:ENSMUSG00000006219|Vega:OTTMUSG00000010344 +74203 Eif4enif1 MGI:MGI:1921453|Ensembl:ENSMUSG00000020454|Vega:OTTMUSG00000000763 +74204 Xpo6 MGI:MGI:2429950|Ensembl:ENSMUSG00000000131|Vega:OTTMUSG00000036479 +74205 Acsl3 MGI:MGI:1921455|Ensembl:ENSMUSG00000032883|Vega:OTTMUSG00000033118 +74206 Sipa1l3 MGI:MGI:1921456|Ensembl:ENSMUSG00000030583|Vega:OTTMUSG00000044352 +74211 1700017B05Rik MGI:MGI:1921461|Ensembl:ENSMUSG00000032300|Vega:OTTMUSG00000063140 +74213 Rbm26 MGI:MGI:1921463|Ensembl:ENSMUSG00000022119|Vega:OTTMUSG00000035210 +74217 1700010G06Rik MGI:MGI:1921467 +74218 1700016H13Rik MGI:MGI:1921468|Ensembl:ENSMUSG00000029320|Vega:OTTMUSG00000029324 +74220 1700009C05Rik MGI:MGI:1921470|Ensembl:ENSMUSG00000101404 +74221 Tex37 MGI:MGI:1921471|Ensembl:ENSMUSG00000051896|Vega:OTTMUSG00000024472 +74222 Sept14 MGI:MGI:1921472|Ensembl:ENSMUSG00000034219|Vega:OTTMUSG00000043646 +74223 1700023D08Rik MGI:MGI:1921473 +74224 1700014D04Rik MGI:MGI:1921474 +74227 1700016A09Rik MGI:MGI:1921477|Ensembl:ENSMUSG00000102737 +74228 1700016C19Rik MGI:MGI:1921478 +74229 Paqr8 MGI:MGI:1921479|Ensembl:ENSMUSG00000025931|Vega:OTTMUSG00000048364 +74230 1700016K19Rik MGI:MGI:1921480|Ensembl:ENSMUSG00000053783|Vega:OTTMUSG00000006221 +74231 1700017H01Rik MGI:MGI:1921481 +74234 N4bp2os MGI:MGI:1921484 +74235 1700020G03Rik MGI:MGI:1921485 +74236 Gsdmcl1 MGI:MGI:1921486|Ensembl:ENSMUSG00000062543 +74237 Tubgcp2 MGI:MGI:1921487|Ensembl:ENSMUSG00000025474|Vega:OTTMUSG00000060571 +74238 Mterf2 MGI:MGI:1921488|Ensembl:ENSMUSG00000049038|Vega:OTTMUSG00000063558 +74239 Iqce MGI:MGI:1921489|Ensembl:ENSMUSG00000036555|Vega:OTTMUSG00000028776 +74241 Chpf MGI:MGI:106576|Ensembl:ENSMUSG00000032997|Vega:OTTMUSG00000019412 +74243 Slx4ip MGI:MGI:1921493|Ensembl:ENSMUSG00000027281|Vega:OTTMUSG00000015558 +74244 Atg7 MGI:MGI:1921494|Ensembl:ENSMUSG00000030314|Vega:OTTMUSG00000043567 +74245 Ctbs MGI:MGI:1921495|Ensembl:ENSMUSG00000028189|Vega:OTTMUSG00000022279 +74246 Gale MGI:MGI:1921496|Ensembl:ENSMUSG00000028671|Vega:OTTMUSG00000009851 +74248 2310003L06Rik MGI:MGI:1921498 +74249 Lrrc2 MGI:MGI:1921499|Ensembl:ENSMUSG00000032495|Vega:OTTMUSG00000052500 +74251 Ankrd9 MGI:MGI:1921501|Ensembl:ENSMUSG00000037904|Vega:OTTMUSG00000032940 +74252 Armc1 MGI:MGI:1921502|Ensembl:ENSMUSG00000027599|Vega:OTTMUSG00000051206 +74253 Klrg2 MGI:MGI:1921503|Ensembl:ENSMUSG00000071537|Vega:OTTMUSG00000056252 +74254 Gpn1 MGI:MGI:1921504|Ensembl:ENSMUSG00000064037|Vega:OTTMUSG00000028269 +74255 Smu1 MGI:MGI:1915546|Ensembl:ENSMUSG00000028409|Vega:OTTMUSG00000006607 +74256 Cyld MGI:MGI:1921506|Ensembl:ENSMUSG00000036712|Vega:OTTMUSG00000061528 +74257 Tspan17 MGI:MGI:1921507|Ensembl:ENSMUSG00000025875|Vega:OTTMUSG00000032673 +74263 1700037C06Rik MGI:MGI:1921513 +74264 Rnf138rt1 MGI:MGI:1921514|Ensembl:ENSMUSG00000083695|Vega:OTTMUSG00000019505 +74266 1700039M15Rik MGI:MGI:1921516 +74267 Iqcf1 MGI:MGI:1921517|Ensembl:ENSMUSG00000066383|Vega:OTTMUSG00000049449 +74268 Aven MGI:MGI:1921518|Ensembl:ENSMUSG00000003604|Vega:OTTMUSG00000015148 +74269 1700063H04Rik MGI:MGI:1921519|Ensembl:ENSMUSG00000040657 +74270 Usp20 MGI:MGI:1921520|Ensembl:ENSMUSG00000026854|Vega:OTTMUSG00000011873 +74271 Mageb5 MGI:MGI:2148169|Ensembl:ENSMUSG00000061392|Vega:OTTMUSG00000017979 +74272 1700054O19Rik MGI:MGI:1921522 +74273 1700064E03Rik - +74276 Cldnd2 MGI:MGI:1921526|Ensembl:ENSMUSG00000038973|Vega:OTTMUSG00000058529 +74277 Chic2 MGI:MGI:1921527|Ensembl:ENSMUSG00000029229|Vega:OTTMUSG00000031089 +74278 1700072F12Rik MGI:MGI:1921528 +74279 1700080O16Rik MGI:MGI:1921529|Ensembl:ENSMUSG00000031118|Vega:OTTMUSG00000017338 +74280 1700084F23Rik MGI:MGI:1921530|Ensembl:ENSMUSG00000099639 +74281 Spatc1 MGI:MGI:1921531|Ensembl:ENSMUSG00000049653 +74282 1700086D15Rik MGI:MGI:1921532 +74283 1700085C21Rik MGI:MGI:1921533|Ensembl:ENSMUSG00000100890 +74284 1700086L19Rik MGI:MGI:1921534|Ensembl:ENSMUSG00000071265 +74285 1700080F18Rik MGI:MGI:1921535 +74286 Tbc1d21 MGI:MGI:1921536|Ensembl:ENSMUSG00000036244|Vega:OTTMUSG00000063280 +74287 Kcmf1 MGI:MGI:1921537|Ensembl:ENSMUSG00000055239|Vega:OTTMUSG00000057869 +74288 Spem1 MGI:MGI:1921538|Ensembl:ENSMUSG00000041165|Vega:OTTMUSG00000005997 +74290 1700102J08Rik MGI:MGI:1921540 +74291 1700092E16Rik MGI:MGI:1921541 +74293 1700095J03Rik MGI:MGI:1921543|Ensembl:ENSMUSG00000085407 +74295 1700092C17Rik MGI:MGI:1921545 +74296 1700093J21Rik MGI:MGI:1921546 +74297 Ccdc182 MGI:MGI:1921547|Ensembl:ENSMUSG00000034031|Vega:OTTMUSG00000001487 +74298 1700108I11Rik MGI:MGI:1921548 +74299 Usp46os1 MGI:MGI:1921549 +74301 1700108N11Rik MGI:MGI:1921551 +74302 Mtmr3 MGI:MGI:1921552|Ensembl:ENSMUSG00000034354|Vega:OTTMUSG00000005070 +74303 1700109K24Rik MGI:MGI:1921553|Ensembl:ENSMUSG00000097267 +74304 1700094M24Rik MGI:MGI:1921554|Ensembl:ENSMUSG00000107895 +74305 1700111N16Rik MGI:MGI:1921555|Ensembl:ENSMUSG00000100511 +74306 Prss46 MGI:MGI:1921556|Ensembl:ENSMUSG00000049719|Vega:OTTMUSG00000031766 +74307 1700092M07Rik MGI:MGI:1921557|Ensembl:ENSMUSG00000090840|Vega:OTTMUSG00000045333 +74309 Osbp2 MGI:MGI:1921559|Ensembl:ENSMUSG00000020435|Vega:OTTMUSG00000005038 +74310 Ube4bos3 MGI:MGI:1921560|Ensembl:ENSMUSG00000085286 +74311 1700113P08Rik MGI:MGI:1921561 +74314 1700120G07Rik MGI:MGI:1921564|Ensembl:ENSMUSG00000100717 +74315 Rnf145 MGI:MGI:1921565|Ensembl:ENSMUSG00000019189|Vega:OTTMUSG00000005471 +74316 Isca2 MGI:MGI:1921566|Ensembl:ENSMUSG00000021241 +74318 Hopx MGI:MGI:1916782|Ensembl:ENSMUSG00000059325|Vega:OTTMUSG00000026555 +74319 Mettl23 MGI:MGI:1921569|Ensembl:ENSMUSG00000090266|Vega:OTTMUSG00000037375 +74320 Wdr33 MGI:MGI:1921570|Ensembl:ENSMUSG00000024400 +74322 Cxxc1 MGI:MGI:1921572|Ensembl:ENSMUSG00000024560 +74325 Cltb MGI:MGI:1921575|Ensembl:ENSMUSG00000047547|Vega:OTTMUSG00000032678 +74326 Hnrnpr MGI:MGI:1891692|Ensembl:ENSMUSG00000066037|Vega:OTTMUSG00000009867 +74327 2900046B09Rik MGI:MGI:1921577 +74328 1700047E10Rik MGI:MGI:1921578 +74330 Dnajc14 MGI:MGI:1921580|Ensembl:ENSMUSG00000025354 +74333 A330040F15Rik MGI:MGI:3698434|Ensembl:ENSMUSG00000086213 +74334 Ranbp10 MGI:MGI:1921584|Ensembl:ENSMUSG00000037415|Vega:OTTMUSG00000062057 +74335 Xrcc3 MGI:MGI:1921585|Ensembl:ENSMUSG00000021287|Vega:OTTMUSG00000027508 +74337 Palm3 MGI:MGI:1921587|Ensembl:ENSMUSG00000047986|Vega:OTTMUSG00000032834 +74338 Slc6a19 MGI:MGI:1921588|Ensembl:ENSMUSG00000021565|Vega:OTTMUSG00000026285 +74340 Ahcyl2 MGI:MGI:1921590|Ensembl:ENSMUSG00000029772|Vega:OTTMUSG00000013488 +74341 G630025P09Rik MGI:MGI:3696719 +74342 Lrrtm1 MGI:MGI:2389173|Ensembl:ENSMUSG00000060780|Vega:OTTMUSG00000034534 +74343 Crtc2 MGI:MGI:1921593|Ensembl:ENSMUSG00000027936|Vega:OTTMUSG00000021260 +74347 Tldc1 MGI:MGI:1921597|Ensembl:ENSMUSG00000034105|Vega:OTTMUSG00000061655 +74348 4632404M16Rik MGI:MGI:1921598 +74349 Fam160a2 MGI:MGI:1921599|Ensembl:ENSMUSG00000044465|Vega:OTTMUSG00000029500 +74351 Ddx23 MGI:MGI:1921601|Ensembl:ENSMUSG00000003360|Vega:OTTMUSG00000034981 +74352 Zfp84 MGI:MGI:107780|Ensembl:ENSMUSG00000046185|Vega:OTTMUSG00000027083 +74354 Lrguk MGI:MGI:1921604|Ensembl:ENSMUSG00000056215|Vega:OTTMUSG00000014768 +74355 Smchd1 MGI:MGI:1921605|Ensembl:ENSMUSG00000024054|Vega:OTTMUSG00000033170 +74356 4931428F04Rik MGI:MGI:1921606|Ensembl:ENSMUSG00000014837|Vega:OTTMUSG00000062041 +74359 4931414P19Rik MGI:MGI:1921609|Ensembl:ENSMUSG00000022179 +74360 Cep57 MGI:MGI:1915551|Ensembl:ENSMUSG00000031922|Vega:OTTMUSG00000033418 +74361 4931429L15Rik MGI:MGI:1921611|Ensembl:ENSMUSG00000056617|Vega:OTTMUSG00000034715 +74362 Spag17 MGI:MGI:1921612|Ensembl:ENSMUSG00000027867|Vega:OTTMUSG00000006935 +74363 4931430N09Rik MGI:MGI:1921613 +74364 4931431C16Rik MGI:MGI:1921614|Ensembl:ENSMUSG00000055061 +74365 Lonrf3 MGI:MGI:1921615|Ensembl:ENSMUSG00000016239|Vega:OTTMUSG00000017249 +74366 4932422M17Rik MGI:MGI:1921616 +74367 4931439C15Rik MGI:MGI:1921617 +74369 Mei1 MGI:MGI:3028590|Ensembl:ENSMUSG00000068117|Vega:OTTMUSG00000045531 +74370 Rptor MGI:MGI:1921620|Ensembl:ENSMUSG00000025583|Vega:OTTMUSG00000004025 +74374 Clec16a MGI:MGI:1921624|Ensembl:ENSMUSG00000068663|Vega:OTTMUSG00000023673 +74375 Gcc1 MGI:MGI:1921625|Ensembl:ENSMUSG00000029708|Vega:OTTMUSG00000021283 +74376 Myo18b MGI:MGI:1921626|Ensembl:ENSMUSG00000072720|Vega:OTTMUSG00000043204 +74377 Hsf2bp MGI:MGI:1921627|Ensembl:ENSMUSG00000002076|Vega:OTTMUSG00000031368 +74380 4932437C15Rik MGI:MGI:1921630 +74381 4932430A15Rik MGI:MGI:1921631 +74382 4932432N04Rik MGI:MGI:1921632 +74383 Ubap2l MGI:MGI:1921633|Ensembl:ENSMUSG00000042520|Vega:OTTMUSG00000052888 +74384 4932433N03Rik MGI:MGI:1921634 +74385 Ap5m1 MGI:MGI:1921635|Ensembl:ENSMUSG00000036291 +74386 Rmi1 MGI:MGI:1921636|Ensembl:ENSMUSG00000035367 +74387 4932438H23Rik MGI:MGI:1921637|Ensembl:ENSMUSG00000039851|Vega:OTTMUSG00000019968 +74388 Dpp8 MGI:MGI:1921638|Ensembl:ENSMUSG00000032393|Vega:OTTMUSG00000062617 +74389 4932429P19Rik MGI:MGI:1921639 +74390 4932434E15Rik MGI:MGI:1921640 +74392 Specc1l MGI:MGI:1921642|Ensembl:ENSMUSG00000033444 +74393 Map10 MGI:MGI:1921643|Ensembl:ENSMUSG00000050930|Vega:OTTMUSG00000045366 +74394 4932441P12Rik MGI:MGI:1921644 +74396 4933407K13Rik MGI:MGI:1921646|Ensembl:ENSMUSG00000087396 +74399 Duxf3 MGI:MGI:1921649 +74400 Zfp819 MGI:MGI:1921650|Ensembl:ENSMUSG00000055102|Vega:OTTMUSG00000022478 +74401 Terb2 MGI:MGI:1921651|Ensembl:ENSMUSG00000027229|Vega:OTTMUSG00000015544 +74403 4933400F21Rik MGI:MGI:1921653 +74404 4933404M09Rik MGI:MGI:1921654 +74405 Efhc2 MGI:MGI:1921655|Ensembl:ENSMUSG00000025038|Vega:OTTMUSG00000016939 +74407 Ttc25 MGI:MGI:1921657|Ensembl:ENSMUSG00000006784|Vega:OTTMUSG00000001993 +74408 4933414I15Rik MGI:MGI:1918374|Ensembl:ENSMUSG00000072983|Vega:OTTMUSG00000007890 +74409 Hyal6 MGI:MGI:1921659|Ensembl:ENSMUSG00000029679|Vega:OTTMUSG00000034246 +74410 Ttll11 MGI:MGI:1921660|Ensembl:ENSMUSG00000026885|Vega:OTTMUSG00000012151 +74411 Plpp6 MGI:MGI:1921661|Ensembl:ENSMUSG00000040105|Vega:OTTMUSG00000033894 +74412 Gle1 MGI:MGI:1921662|Ensembl:ENSMUSG00000019715|Vega:OTTMUSG00000016705 +74413 Tc2n MGI:MGI:1921663|Ensembl:ENSMUSG00000021187|Vega:OTTMUSG00000033025 +74414 Polr3c MGI:MGI:1921664|Ensembl:ENSMUSG00000028099|Vega:OTTMUSG00000033832 +74415 4932442E05Rik MGI:MGI:1921665 +74418 4932702M13Rik MGI:MGI:1921668 +74419 Tktl2 MGI:MGI:1921669|Ensembl:ENSMUSG00000025519|Vega:OTTMUSG00000043647 +74420 4933406P04Rik MGI:MGI:1921670 +74424 Tmc5 MGI:MGI:1921674|Ensembl:ENSMUSG00000030650|Vega:OTTMUSG00000030889 +74425 4933402J15Rik MGI:MGI:1921675 +74426 4933402D24Rik MGI:MGI:1921676|Ensembl:ENSMUSG00000025961|Vega:OTTMUSG00000013922 +74427 Eaf1 MGI:MGI:1921677|Ensembl:ENSMUSG00000021890 +74429 4930478P22Rik MGI:MGI:1922154|Ensembl:ENSMUSG00000106762 +74430 4930452B06Rik MGI:MGI:1926154|Ensembl:ENSMUSG00000021747|Vega:OTTMUSG00000015260 +74434 Sohlh2 MGI:MGI:1921684|Ensembl:ENSMUSG00000027794|Vega:OTTMUSG00000023038 +74435 Lrriq3 MGI:MGI:1921685|Ensembl:ENSMUSG00000028182|Vega:OTTMUSG00000052254 +74437 4933402E13Rik MGI:MGI:1921687|Ensembl:ENSMUSG00000045330|Vega:OTTMUSG00000017596 +74438 Clvs1 MGI:MGI:1921688|Ensembl:ENSMUSG00000041216|Vega:OTTMUSG00000004383 +74440 Cmip MGI:MGI:1921690|Ensembl:ENSMUSG00000034390|Vega:OTTMUSG00000061721 +74441 Slco6c1 MGI:MGI:1921691|Ensembl:ENSMUSG00000026331|Vega:OTTMUSG00000048826 +74442 Sgms2 MGI:MGI:1921692|Ensembl:ENSMUSG00000050931|Vega:OTTMUSG00000022630 +74443 P4htm MGI:MGI:1921693|Ensembl:ENSMUSG00000006675|Vega:OTTMUSG00000050767 +74445 4933412A08Rik MGI:MGI:1921695 +74446 Slc9b1 MGI:MGI:1921696|Ensembl:ENSMUSG00000050150|Vega:OTTMUSG00000034178 +74448 Arl13a MGI:MGI:1921698|Ensembl:ENSMUSG00000052549|Vega:OTTMUSG00000019162 +74449 4933408M05Rik MGI:MGI:1921699 +74450 Pank2 MGI:MGI:1921700|Ensembl:ENSMUSG00000037514|Vega:OTTMUSG00000016043 +74451 Pgs1 MGI:MGI:1921701|Ensembl:ENSMUSG00000017715|Vega:OTTMUSG00000003736 +74452 4933413C19Rik MGI:MGI:1921702 +74453 Cfap53 MGI:MGI:1921703|Ensembl:ENSMUSG00000035394|Vega:OTTMUSG00000039801 +74454 4933408J17Rik MGI:MGI:1921704|Ensembl:ENSMUSG00000097407 +74455 Nsun6 MGI:MGI:1921705|Ensembl:ENSMUSG00000026707|Vega:OTTMUSG00000011386 +74456 4933424G05Rik MGI:MGI:1921706 +74457 LOC74457 - +74458 4933425B07Rik MGI:MGI:1921708 +74460 Gsdmcl-ps MGI:MGI:1921710|Ensembl:ENSMUSG00000100127 +74461 4933416A02Rik MGI:MGI:1921711 +74463 Exoc3l2 MGI:MGI:1921713|Ensembl:ENSMUSG00000011263|Vega:OTTMUSG00000033723 +74464 Zswim5 MGI:MGI:1921714|Ensembl:ENSMUSG00000033948|Vega:OTTMUSG00000009781 +74465 4933421H12Rik MGI:MGI:1921715 +74466 Mfsd13b MGI:MGI:1921716|Ensembl:ENSMUSG00000030877|Vega:OTTMUSG00000027361 +74467 Pus10 MGI:MGI:1921717|Ensembl:ENSMUSG00000020280|Vega:OTTMUSG00000005283 +74468 Hyal5 MGI:MGI:1921718|Ensembl:ENSMUSG00000029678|Vega:OTTMUSG00000056005 +74469 Taf7l MGI:MGI:1921719|Ensembl:ENSMUSG00000009596|Vega:OTTMUSG00000019305 +74470 Cep72 MGI:MGI:1921720|Ensembl:ENSMUSG00000021572 +74471 4933440N22Rik MGI:MGI:1921721 +74472 Stpg3 MGI:MGI:1921722|Ensembl:ENSMUSG00000036770|Vega:OTTMUSG00000011805 +74473 4933433H22Rik MGI:MGI:1921723 +74474 5230400M06Rik MGI:MGI:1921724 +74475 4933431K23Rik MGI:MGI:1921725 +74476 4933439C10Rik MGI:MGI:1921726|Ensembl:ENSMUSG00000072893 +74477 4933427D14Rik MGI:MGI:1921727|Ensembl:ENSMUSG00000020807|Vega:OTTMUSG00000006100 +74478 Snx29 MGI:MGI:1921728|Ensembl:ENSMUSG00000071669|Vega:OTTMUSG00000027398 +74479 Snx11 MGI:MGI:1921729|Ensembl:ENSMUSG00000020876|Vega:OTTMUSG00000001970 +74480 Samd4 MGI:MGI:1921730|Ensembl:ENSMUSG00000021838|Vega:OTTMUSG00000023718 +74481 Batf2 MGI:MGI:1921731|Ensembl:ENSMUSG00000039699|Vega:OTTMUSG00000018629 +74482 Ifitm7 MGI:MGI:1921732|Ensembl:ENSMUSG00000065968|Vega:OTTMUSG00000026343 +74484 Rbm31y MGI:MGI:1921734|Ensembl:ENSMUSG00000095365|Vega:OTTMUSG00000048981 +74485 Lrrc71 MGI:MGI:1921735|Ensembl:ENSMUSG00000023084|Vega:OTTMUSG00000036959 +74486 Osbpl10 MGI:MGI:1921736|Ensembl:ENSMUSG00000040875|Vega:OTTMUSG00000043335 +74487 5430405H02Rik MGI:MGI:1921737|Ensembl:ENSMUSG00000085741 +74488 Lrrc15 MGI:MGI:1921738|Ensembl:ENSMUSG00000052316|Vega:OTTMUSG00000023618 +74489 5430421F17Rik MGI:MGI:1921739|Ensembl:ENSMUSG00000110140 +74490 Mamstr MGI:MGI:1921740|Ensembl:ENSMUSG00000042918|Vega:OTTMUSG00000034061 +74491 5430420F09Rik MGI:MGI:1921741 +74492 Kbtbd13 MGI:MGI:1921742|Ensembl:ENSMUSG00000054978|Vega:OTTMUSG00000044916 +74493 Tnks2 MGI:MGI:1921743|Ensembl:ENSMUSG00000024811|Vega:OTTMUSG00000035920 +74498 Gorasp1 MGI:MGI:1921748|Ensembl:ENSMUSG00000032513|Vega:OTTMUSG00000062302 +74499 Sost MGI:MGI:1921749|Ensembl:ENSMUSG00000001494|Vega:OTTMUSG00000002135 +74500 5430439C14Rik MGI:MGI:1921750 +74502 5430404G13Rik MGI:MGI:1921752 +74504 Fam53a MGI:MGI:1919225|Ensembl:ENSMUSG00000037339|Vega:OTTMUSG00000025081 +74507 5530400K19Rik MGI:MGI:1921757 +74509 6820402I19Rik MGI:MGI:1921759 +74511 Lrrc17 MGI:MGI:1921761|Ensembl:ENSMUSG00000039883|Vega:OTTMUSG00000053220 +74513 Neto2 MGI:MGI:1921763|Ensembl:ENSMUSG00000036902|Vega:OTTMUSG00000061423 +74516 A730049H05Rik MGI:MGI:1921766|Ensembl:ENSMUSG00000048636 +74517 7420700N18Rik MGI:MGI:1921767|Ensembl:ENSMUSG00000109915 +74518 8430419K02Rik MGI:MGI:1921768 +74519 Cyp2j9 MGI:MGI:1921769|Ensembl:ENSMUSG00000015224|Vega:OTTMUSG00000007935 +74521 Ppp4r4 MGI:MGI:1921771|Ensembl:ENSMUSG00000021209|Vega:OTTMUSG00000049396 +74522 Morc2a MGI:MGI:1921772|Ensembl:ENSMUSG00000034543|Vega:OTTMUSG00000005034 +74525 Fam234b MGI:MGI:1921775|Ensembl:ENSMUSG00000030207|Vega:OTTMUSG00000024065 +74528 Mgme1 MGI:MGI:1921778|Ensembl:ENSMUSG00000027424|Vega:OTTMUSG00000003459 +74529 8430422H06Rik MGI:MGI:1921779 +74530 9030612E09Rik MGI:MGI:1921780|Ensembl:ENSMUSG00000045008 +74531 9030405F24Rik MGI:MGI:1921781 +74533 Gzf1 MGI:MGI:1921783|Ensembl:ENSMUSG00000027439|Vega:OTTMUSG00000015714 +74534 8430428J23Rik MGI:MGI:1921784 +74536 9030409C19Rik MGI:MGI:1921786 +74538 9030409K20Rik MGI:MGI:1921788 +74539 9030425L15Rik MGI:MGI:1921789 +74541 8430437L04Rik MGI:MGI:1921791|Ensembl:ENSMUSG00000085252 +74542 9030625N01Rik MGI:MGI:1921792 +74545 9030417H13Rik MGI:MGI:1921795 +74547 9030622M22Rik MGI:MGI:1921797 +74548 Gsdmc4 MGI:MGI:1921798|Ensembl:ENSMUSG00000055748|Vega:OTTMUSG00000045284 +74549 Mau2 MGI:MGI:1921799|Ensembl:ENSMUSG00000031858|Vega:OTTMUSG00000062224 +74550 9130007G19Rik MGI:MGI:1921800 +74551 Pck2 MGI:MGI:1860456|Ensembl:ENSMUSG00000040618 +74552 Nipal3 MGI:MGI:1921802|Ensembl:ENSMUSG00000028803|Vega:OTTMUSG00000009737 +74554 9130002K18Rik MGI:MGI:1921804 +74555 9130401L11Rik MGI:MGI:1921805 +74556 Themis3 MGI:MGI:1921806|Ensembl:ENSMUSG00000024105|Vega:OTTMUSG00000029801 +74558 Gvin1 MGI:MGI:1921808|Ensembl:ENSMUSG00000045868|Vega:OTTMUSG00000044633 +74559 Elovl7 MGI:MGI:1921809|Ensembl:ENSMUSG00000021696 +74560 9130414P19Rik MGI:MGI:1921810 +74561 Nkx6-3 MGI:MGI:1921811|Ensembl:ENSMUSG00000063672|Vega:OTTMUSG00000028462 +74562 Fer1l4 MGI:MGI:1921812|Ensembl:ENSMUSG00000013338|Vega:OTTMUSG00000016025 +74563 Rasgef1c MGI:MGI:1921813|Ensembl:ENSMUSG00000020374|Vega:OTTMUSG00000005571 +74564 9130022E09 - +74567 9130015G15Rik MGI:MGI:1921817 +74568 Mlkl MGI:MGI:1921818|Ensembl:ENSMUSG00000012519|Vega:OTTMUSG00000031320 +74569 Ttc17 MGI:MGI:1921819|Ensembl:ENSMUSG00000027194|Vega:OTTMUSG00000014442 +74570 Zkscan1 MGI:MGI:1921820|Ensembl:ENSMUSG00000029729|Vega:OTTMUSG00000022628 +74571 Kcnk16 MGI:MGI:1921821|Ensembl:ENSMUSG00000023387 +74574 Lvrn MGI:MGI:1921824|Ensembl:ENSMUSG00000024481 +74575 4833406M21Rik MGI:MGI:1921825 +74576 4731417B20Rik MGI:MGI:1921826 +74577 Glb1l MGI:MGI:1921827|Ensembl:ENSMUSG00000026200|Vega:OTTMUSG00000021564 +74578 4833408G04Rik MGI:MGI:1921828 +74579 4833419E13Rik MGI:MGI:1921829 +74580 Pyroxd2 MGI:MGI:1921830|Ensembl:ENSMUSG00000060224 +74583 4833411I10Rik MGI:MGI:1921833 +74584 4833413G10Rik MGI:MGI:1921834 +74585 Sppl3 MGI:MGI:1891433|Ensembl:ENSMUSG00000029550|Vega:OTTMUSG00000014619 +74586 4833420L08Rik MGI:MGI:1921836 +74587 4833422B07Rik MGI:MGI:1921837 +74589 Kbtbd12 MGI:MGI:1918481|Ensembl:ENSMUSG00000033182|Vega:OTTMUSG00000027855 +74591 Abca12 MGI:MGI:2676312|Ensembl:ENSMUSG00000050296|Vega:OTTMUSG00000048805 +74594 4833421K07Rik MGI:MGI:1921844 +74596 Cds1 MGI:MGI:1921846|Ensembl:ENSMUSG00000029330|Vega:OTTMUSG00000029627 +74597 4833418N02Rik MGI:MGI:1921847|Ensembl:ENSMUSG00000085287 +74600 Mrpl47 MGI:MGI:1921850|Ensembl:ENSMUSG00000037531|Vega:OTTMUSG00000028124 +74601 4833427F10Rik MGI:MGI:1921851|Ensembl:ENSMUSG00000092171 +74602 4833428L15Rik MGI:MGI:1921852|Ensembl:ENSMUSG00000097074 +74603 Cd200r3 MGI:MGI:1921853|Ensembl:ENSMUSG00000036172|Vega:OTTMUSG00000014973 +74604 4833417J20Rik MGI:MGI:1921854 +74607 4833412K13Rik MGI:MGI:1921857 +74610 Abcb8 MGI:MGI:1351667|Ensembl:ENSMUSG00000028973|Vega:OTTMUSG00000024149 +74612 4833410I11Rik MGI:MGI:1921862 +74613 4833412C15Rik MGI:MGI:1921863 +74614 Ocstamp MGI:MGI:1921864|Ensembl:ENSMUSG00000027670|Vega:OTTMUSG00000001116 +74616 Scrn3 MGI:MGI:1921866|Ensembl:ENSMUSG00000008226|Vega:OTTMUSG00000013431 +74617 Scpep1 MGI:MGI:1921867|Ensembl:ENSMUSG00000000278|Vega:OTTMUSG00000001271 +74619 4930432B10Rik MGI:MGI:1921869 +74621 4930432L08Rik MGI:MGI:1921871 +74622 4930429F11Rik MGI:MGI:1921872 +74624 4930429D17Rik MGI:MGI:1921874|Ensembl:ENSMUSG00000104956 +74626 Tmem81 MGI:MGI:1921876|Ensembl:ENSMUSG00000048174|Vega:OTTMUSG00000049392 +74627 4930413E15Rik MGI:MGI:1921877|Ensembl:ENSMUSG00000107144 +74628 4930423C22Rik MGI:MGI:1921878 +74629 4930426L09Rik MGI:MGI:1921879|Ensembl:ENSMUSG00000026736 +74630 4930432N10Rik MGI:MGI:1921880 +74632 4930428F12Rik MGI:MGI:1921882 +74633 4930429F24Rik MGI:MGI:1921883|Ensembl:ENSMUSG00000086918 +74634 4930423D22Rik MGI:MGI:1921884 +74635 4930425O10Rik MGI:MGI:1921885|Ensembl:ENSMUSG00000105838 +74637 Shpk MGI:MGI:1921887|Ensembl:ENSMUSG00000005951|Vega:OTTMUSG00000006126 +74639 4930429N05Rik MGI:MGI:1921889 +74641 4930431C11Rik MGI:MGI:1921891 +74643 4930422I22Rik MGI:MGI:1921893 +74644 4930426D05Rik MGI:MGI:1921894 +74645 Fam46c MGI:MGI:1921895|Ensembl:ENSMUSG00000044468|Vega:OTTMUSG00000006991 +74646 Spsb1 MGI:MGI:1921896|Ensembl:ENSMUSG00000039911|Vega:OTTMUSG00000010263 +74647 4930432O09Rik MGI:MGI:1921897|Ensembl:ENSMUSG00000112846 +74648 S100pbp MGI:MGI:1921898|Ensembl:ENSMUSG00000040928|Vega:OTTMUSG00000009625 +74649 Cpa5 MGI:MGI:1921899|Ensembl:ENSMUSG00000029788|Vega:OTTMUSG00000014389 +74650 4930433M22Rik MGI:MGI:1921900 +74651 4930435M08Rik MGI:MGI:1921901 +74652 4930453J04Rik MGI:MGI:1921902 +74653 Pomk MGI:MGI:1921903|Ensembl:ENSMUSG00000037251|Vega:OTTMUSG00000060877 +74654 4930455H04Rik MGI:MGI:1921904|Ensembl:ENSMUSG00000080907|Vega:OTTMUSG00000029791 +74658 4930445G23Rik MGI:MGI:1921908 +74660 4930442J19Rik MGI:MGI:1921910|Ensembl:ENSMUSG00000087609 +74661 Pard3bos1 MGI:MGI:1921911 +74662 4930448K20Rik MGI:MGI:1921912|Ensembl:ENSMUSG00000082843 +74663 4930435E12Rik MGI:MGI:1921913|Ensembl:ENSMUSG00000022798|Vega:OTTMUSG00000026295 +74664 4930433J02Rik MGI:MGI:1921914 +74665 Drc3 MGI:MGI:1921915|Ensembl:ENSMUSG00000056598|Vega:OTTMUSG00000005813 +74666 4930432K21Rik MGI:MGI:1921916|Ensembl:ENSMUSG00000008129|Vega:OTTMUSG00000030573 +74667 4930434J06Rik MGI:MGI:1921917 +74668 4933409F18Rik MGI:MGI:1918376|Ensembl:ENSMUSG00000113218 +74670 Zfp943 MGI:MGI:1921920|Ensembl:ENSMUSG00000053347|Vega:OTTMUSG00000031582 +74671 4930448D08Rik MGI:MGI:1921921 +74672 4930449A18Rik MGI:MGI:1921922 +74673 Spdye4a MGI:MGI:1921923|Ensembl:ENSMUSG00000039296|Vega:OTTMUSG00000031883 +74675 Ptchd3 MGI:MGI:1921925|Ensembl:ENSMUSG00000039198|Vega:OTTMUSG00000007614 +74676 4930456A14Rik MGI:MGI:1921926 +74678 4930456G14Rik MGI:MGI:1921928 +74680 4930435F18Rik MGI:MGI:1921930 +74681 4930448E22Rik MGI:MGI:1921931 +74682 Wdr35 MGI:MGI:1921932|Ensembl:ENSMUSG00000066643|Vega:OTTMUSG00000027013 +74684 4930451G09Rik MGI:MGI:1921934 +74685 Lrrc74b MGI:MGI:1921935|Ensembl:ENSMUSG00000022759|Vega:OTTMUSG00000023664 +74686 Slc25a54 MGI:MGI:1921936|Ensembl:ENSMUSG00000027880|Vega:OTTMUSG00000007309 +74687 4930443O20Rik MGI:MGI:1921937|Ensembl:ENSMUSG00000086969 +74688 4930453L07Rik MGI:MGI:1921938|Ensembl:ENSMUSG00000109215 +74689 4930440C22Rik MGI:MGI:1921939|Ensembl:ENSMUSG00000100518 +74690 4930459I23Rik MGI:MGI:1921940 +74691 Tdrd9 MGI:MGI:1921941|Ensembl:ENSMUSG00000054003|Vega:OTTMUSG00000049977 +74692 4930442P07Rik MGI:MGI:1921942 +74693 4930509J09Rik MGI:MGI:1921943|Ensembl:ENSMUSG00000102362 +74694 Tbc1d30 MGI:MGI:1921944|Ensembl:ENSMUSG00000052302 +74695 4930510E17Rik MGI:MGI:1921945 +74696 4930519A11Rik MGI:MGI:1921946 +74700 4930524O08Rik MGI:MGI:1921950|Ensembl:ENSMUSG00000098627 +74702 4930517E11Rik MGI:MGI:1921952|Ensembl:ENSMUSG00000085496 +74703 Ccdc7a MGI:MGI:1921953|Ensembl:ENSMUSG00000025808|Vega:OTTMUSG00000022634 +74704 4930518I15Rik MGI:MGI:1921954 +74705 4930505O19Rik MGI:MGI:1921955 +74706 4930507D05Rik MGI:MGI:1921956|Ensembl:ENSMUSG00000097129 +74707 4930521G14Rik MGI:MGI:1921957 +74708 Pih1d3 MGI:MGI:1921958|Ensembl:ENSMUSG00000026063|Vega:OTTMUSG00000026559 +74709 4930505O20Rik MGI:MGI:1921959 +74711 Ttll9 MGI:MGI:1913589|Ensembl:ENSMUSG00000074673|Vega:OTTMUSG00000015923 +74712 4930511A02Rik MGI:MGI:1921962|Ensembl:ENSMUSG00000097841 +74713 4930519E07Rik MGI:MGI:1921963 +74714 4930511J24Rik MGI:MGI:1921964 +74715 4930521O11Rik MGI:MGI:1921965|Ensembl:ENSMUSG00000091676|Vega:OTTMUSG00000035717 +74716 Wbp2nl MGI:MGI:1921966|Ensembl:ENSMUSG00000022455 +74717 Spata17 MGI:MGI:1921967|Ensembl:ENSMUSG00000026611|Vega:OTTMUSG00000022987 +74718 Snx16 MGI:MGI:1921968|Ensembl:ENSMUSG00000027534|Vega:OTTMUSG00000051030 +74720 Tmem114 MGI:MGI:1921970|Ensembl:ENSMUSG00000022715 +74721 4930519P11Rik MGI:MGI:1921971 +74722 4930517J16Rik MGI:MGI:1921972 +74724 4930512B01Rik MGI:MGI:1921974 +74725 4930524B17Rik MGI:MGI:1921975|Ensembl:ENSMUSG00000107217 +74726 4930523O13Rik MGI:MGI:1921976 +74727 4930517G19Rik MGI:MGI:1921977 +74728 5033428C03Rik MGI:MGI:1921978 +74729 Setmar MGI:MGI:1921979|Ensembl:ENSMUSG00000034639|Vega:OTTMUSG00000017300 +74732 Stx11 MGI:MGI:1921982|Ensembl:ENSMUSG00000039232 +74733 5033425B01Rik MGI:MGI:1921983 +74734 Rhoh MGI:MGI:1921984|Ensembl:ENSMUSG00000029204|Vega:OTTMUSG00000055241 +74735 Trim14 MGI:MGI:1921985|Ensembl:ENSMUSG00000039853|Vega:OTTMUSG00000006913 +74737 Pcf11 MGI:MGI:1919579|Ensembl:ENSMUSG00000041328|Vega:OTTMUSG00000029291 +74739 5830400J07Rik MGI:MGI:1921989 +74741 C2cd5 MGI:MGI:1921991|Ensembl:ENSMUSG00000030279|Vega:OTTMUSG00000057141 +74742 5830411J07Rik MGI:MGI:1921992 +74743 5830403F22Rik MGI:MGI:1921993 +74744 5830408C22Rik MGI:MGI:1921994 +74746 5830407F19Rik MGI:MGI:1921996 +74747 Ddit4 MGI:MGI:1921997|Ensembl:ENSMUSG00000020108 +74748 Slamf8 MGI:MGI:1921998|Ensembl:ENSMUSG00000053318|Vega:OTTMUSG00000050153 +74749 5830405M20Rik MGI:MGI:1921999 +74750 5830410O09Rik MGI:MGI:1922000 +74753 Trmo MGI:MGI:1922003|Ensembl:ENSMUSG00000028331|Vega:OTTMUSG00000006888 +74754 Dhcr24 MGI:MGI:1922004|Ensembl:ENSMUSG00000034926|Vega:OTTMUSG00000008196 +74756 5830408B19Rik MGI:MGI:1922006 +74757 5830416I19Rik MGI:MGI:1922007|Ensembl:ENSMUSG00000106219 +74760 Rab3il1 MGI:MGI:1922010|Ensembl:ENSMUSG00000024663|Vega:OTTMUSG00000028255 +74761 Mxra8 MGI:MGI:1922011|Ensembl:ENSMUSG00000029070|Vega:OTTMUSG00000010893 +74762 Mdga1 MGI:MGI:1922012|Ensembl:ENSMUSG00000043557|Vega:OTTMUSG00000035346 +74763 Naa60 MGI:MGI:1922013|Ensembl:ENSMUSG00000005982|Vega:OTTMUSG00000025497 +74764 Klc4 MGI:MGI:1922014|Ensembl:ENSMUSG00000003546 +74766 Yipf2 MGI:MGI:1922016|Ensembl:ENSMUSG00000032182|Vega:OTTMUSG00000063456 +74769 Pik3cb MGI:MGI:1922019|Ensembl:ENSMUSG00000032462|Vega:OTTMUSG00000021081 +74770 Hhatl MGI:MGI:1922020|Ensembl:ENSMUSG00000032523|Vega:OTTMUSG00000062671 +74772 Atp13a2 MGI:MGI:1922022|Ensembl:ENSMUSG00000036622|Vega:OTTMUSG00000010089 +74775 Lmbr1l MGI:MGI:1289247|Ensembl:ENSMUSG00000022999|Vega:OTTMUSG00000024113 +74776 Ppa2 MGI:MGI:1922026|Ensembl:ENSMUSG00000028013|Vega:OTTMUSG00000029590 +74777 Selenon MGI:MGI:2151208|Ensembl:ENSMUSG00000050989|Vega:OTTMUSG00000011213 +74778 Rrp7a MGI:MGI:1922028|Ensembl:ENSMUSG00000018040|Vega:OTTMUSG00000035729 +74781 Wipi2 MGI:MGI:1923831|Ensembl:ENSMUSG00000029578|Vega:OTTMUSG00000026064 +74782 Glt8d2 MGI:MGI:1922032|Ensembl:ENSMUSG00000020251|Vega:OTTMUSG00000024260 +74838 Naa15 MGI:MGI:1922088|Ensembl:ENSMUSG00000063273|Vega:OTTMUSG00000051598 +74840 Manf MGI:MGI:1922090|Ensembl:ENSMUSG00000032575|Vega:OTTMUSG00000032651 +74841 Usp38 MGI:MGI:1922091|Ensembl:ENSMUSG00000038250|Vega:OTTMUSG00000061341 +74842 4833419G08Rik MGI:MGI:1922092 +74843 Mss51 MGI:MGI:1922093|Ensembl:ENSMUSG00000021815 +74844 4833447I15Rik MGI:MGI:1922094 +74845 4930404K13Rik MGI:MGI:1922095 +74846 4930405A21Rik MGI:MGI:1922096|Ensembl:ENSMUSG00000086638 +74847 Meikin MGI:MGI:1922097|Ensembl:ENSMUSG00000020332|Vega:OTTMUSG00000005667 +74848 4833446E11Rik MGI:MGI:1922098 +74849 4930412F12Rik MGI:MGI:1922099|Ensembl:ENSMUSG00000110289 +74851 Spin2-ps1 MGI:MGI:3650966 +74852 4930402D18Rik MGI:MGI:1922102 +74854 4930402F06Rik MGI:MGI:1922104|Ensembl:ENSMUSG00000079421|Vega:OTTMUSG00000012255 +74855 Fam228a MGI:MGI:1922105|Ensembl:ENSMUSG00000079177 +74856 Pip5k1bos MGI:MGI:1922106 +74857 4930448O17Rik MGI:MGI:1922107 +74858 4930451E06Rik MGI:MGI:1922108 +74859 4930455B14Rik MGI:MGI:1922109|Ensembl:ENSMUSG00000097898 +74862 4930447F04Rik MGI:MGI:1922112 +74863 4930447C11Rik MGI:MGI:1922113 +74864 4930449E01Rik MGI:MGI:1922114|Ensembl:ENSMUSG00000022116 +74867 4930445B03Rik MGI:MGI:1922117 +74868 Tmem65 MGI:MGI:1922118|Ensembl:ENSMUSG00000062373|Vega:OTTMUSG00000020984 +74869 4930447G04Rik MGI:MGI:1922119 +74872 4930448H16Rik MGI:MGI:1922122|Ensembl:ENSMUSG00000089879 +74873 4930443G03Rik MGI:MGI:1922123 +74874 4930444E06Rik MGI:MGI:1922124 +74877 4930458K08Rik MGI:MGI:1922127 +74879 4930461G14Rik MGI:MGI:1922129|Ensembl:ENSMUSG00000097651 +74880 4930445B16Rik MGI:MGI:1922130 +74881 4930459C07Rik MGI:MGI:1922131|Ensembl:ENSMUSG00000112762 +74882 4930461L14Rik MGI:MGI:1922132 +74883 4930461C15Rik MGI:MGI:1922133 +74884 Cdrt4os1 MGI:MGI:1922134|Ensembl:ENSMUSG00000087604 +74885 4930453O03Rik MGI:MGI:1922135 +74886 4930445K14Rik MGI:MGI:1922136 +74887 4930456J16Rik MGI:MGI:1922137 +74888 Saxo1os MGI:MGI:1922138|Ensembl:ENSMUSG00000085108 +74890 Morn3 MGI:MGI:1922140|Ensembl:ENSMUSG00000029477|Vega:OTTMUSG00000026864 +74891 4930439G18Rik MGI:MGI:1922141 +74892 4930447A16Rik MGI:MGI:1922142|Ensembl:ENSMUSG00000022288|Vega:OTTMUSG00000028028 +74893 4930453C13Rik MGI:MGI:1922143 +74894 4930442H23Rik MGI:MGI:1922144 +74895 Ccdc181 MGI:MGI:1922145|Ensembl:ENSMUSG00000026578|Vega:OTTMUSG00000022174 +74896 4930405A10Rik MGI:MGI:1921060 +74897 4930448I06Rik MGI:MGI:1922147|Ensembl:ENSMUSG00000104072 +74898 4930456K20Rik MGI:MGI:1922148 +74901 Kbtbd11 MGI:MGI:1922151|Ensembl:ENSMUSG00000055675|Vega:OTTMUSG00000044892 +74905 4930477N07Rik MGI:MGI:1922155|Ensembl:ENSMUSG00000112155 +74906 4930478M09Rik MGI:MGI:1922156 +74907 4930483C01Rik MGI:MGI:1922157 +74909 4930467J12Rik MGI:MGI:1922159 +74910 4930480E11Rik MGI:MGI:1922160|Ensembl:ENSMUSG00000035651|Vega:OTTMUSG00000017879 +74911 4930485E13Rik MGI:MGI:1922161 +74912 4930471E19Rik MGI:MGI:1922162 +74914 Cylc2 MGI:MGI:1922164|Ensembl:ENSMUSG00000039555|Vega:OTTMUSG00000006967 +74915 Atp6v1e2 MGI:MGI:1922165|Ensembl:ENSMUSG00000053375 +74916 1700066O22Rik MGI:MGI:1920651|Ensembl:ENSMUSG00000085800 +74917 4930474M22Rik MGI:MGI:1922167 +74918 Iqca MGI:MGI:1922168|Ensembl:ENSMUSG00000026301|Vega:OTTMUSG00000048350 +74919 Slc35f6 MGI:MGI:1922169|Ensembl:ENSMUSG00000029175|Vega:OTTMUSG00000022284 +74923 4930471D02Rik MGI:MGI:1922173 +74925 4930479D17Rik MGI:MGI:1922175|Ensembl:ENSMUSG00000085238 +74926 4930473H19Rik MGI:MGI:1922176 +74927 Pmis2 MGI:MGI:1922177|Ensembl:ENSMUSG00000049761|Vega:OTTMUSG00000047532 +74928 4930467K11Rik MGI:MGI:1922178|Ensembl:ENSMUSG00000097370 +74929 4930487N04Rik MGI:MGI:1922179 +74930 4930480M12Rik MGI:MGI:1922180|Ensembl:ENSMUSG00000113115 +74931 4930481A15Rik MGI:MGI:1922181|Ensembl:ENSMUSG00000086938 +74934 Armc4 MGI:MGI:1922184|Ensembl:ENSMUSG00000061802 +74935 4930480K02Rik MGI:MGI:1922185 +74936 4930474B08Rik MGI:MGI:1922186 +74937 4930481B07Rik MGI:MGI:1922187 +74939 4930471G24Rik MGI:MGI:1922189 +74940 4930474A20Rik MGI:MGI:1922190 +74941 4930503H13Rik MGI:MGI:1922191 +74942 4930503O07Rik MGI:MGI:1922192|Ensembl:ENSMUSG00000103692 +74945 Acss2os MGI:MGI:1922195|Ensembl:ENSMUSG00000086529 +74947 Kif4-ps MGI:MGI:1922197|Ensembl:ENSMUSG00000092054 +74949 4930477E14Rik MGI:MGI:1922199 +74951 4930502A04Rik MGI:MGI:1922201|Ensembl:ENSMUSG00000111303 +74953 4930483K19Rik MGI:MGI:1922203|Ensembl:ENSMUSG00000086241 +74954 4930503E14Rik MGI:MGI:1922204|Ensembl:ENSMUSG00000072595|Vega:OTTMUSG00000036392 +74956 4930484I04Rik MGI:MGI:1922206 +74957 4930486N12Rik MGI:MGI:1922207 +74959 Platr14 MGI:MGI:1922209|Ensembl:ENSMUSG00000086454 +74963 4930470F04Rik MGI:MGI:1922213 +74965 4930465C05Rik MGI:MGI:1922215 +74966 4930471G03Rik MGI:MGI:1922216 +74967 4930474H20Rik MGI:MGI:1922217 +74968 4930465M20Rik MGI:MGI:1922218|Ensembl:ENSMUSG00000085641 +74969 4930466K18Rik MGI:MGI:1922219 +74970 4930483O08Rik MGI:MGI:1922220|Ensembl:ENSMUSG00000109816 +74971 4930488B22Rik MGI:MGI:1922221|Ensembl:ENSMUSG00000092578 +74972 4930500A05Rik MGI:MGI:1922222 +74973 4930500L23Rik MGI:MGI:1922223|Ensembl:ENSMUSG00000106056 +74974 4930502M04Rik MGI:MGI:1922224 +74975 4930502C17Rik MGI:MGI:1922225 +74978 Lrriq1 MGI:MGI:1922228|Ensembl:ENSMUSG00000019892|Vega:OTTMUSG00000032477 +74980 4930465K09Rik MGI:MGI:1922230 +74981 4930480I08Rik MGI:MGI:1922231 +74982 1700100I10Rik MGI:MGI:1920812 +74983 4930477O15Rik MGI:MGI:1922233 +74984 4930478M13Rik MGI:MGI:1922234 +74986 4930480C01Rik MGI:MGI:1922236 +74987 Cldn34d MGI:MGI:1922237|Ensembl:ENSMUSG00000079525|Vega:OTTMUSG00000017769 +74988 4930480G23Rik MGI:MGI:1922238 +74989 Csmd2os MGI:MGI:1922239 +74990 4930500E03Rik MGI:MGI:1922240 +74991 4930500H12Rik MGI:MGI:1922241 +74992 4930487H11Rik MGI:MGI:1922242 +74995 4930502E09Rik MGI:MGI:1922245|Ensembl:ENSMUSG00000086799 +74996 Usp47 MGI:MGI:1922246|Ensembl:ENSMUSG00000059263|Vega:OTTMUSG00000060217 +74998 Rab11fip2 MGI:MGI:1922248|Ensembl:ENSMUSG00000040022|Vega:OTTMUSG00000036573 +75001 4930482G09Rik MGI:MGI:1922251 +75002 Tmprss12 MGI:MGI:1922252|Ensembl:ENSMUSG00000045631 +75004 4930467D19Rik MGI:MGI:1922254 +75006 4930486A15Rik MGI:MGI:1922256 +75007 Mindy1 MGI:MGI:1922257|Ensembl:ENSMUSG00000038712|Vega:OTTMUSG00000022055 +75010 Tmbim7 MGI:MGI:1922305|Ensembl:ENSMUSG00000014529|Vega:OTTMUSG00000024213 +75011 4930488N24Rik MGI:MGI:1922261 +75012 4930500F10Rik MGI:MGI:1922262 +75013 4930502E18Rik MGI:MGI:1922263|Ensembl:ENSMUSG00000055555|Vega:OTTMUSG00000017384 +75015 4930503B20Rik MGI:MGI:1922264|Ensembl:ENSMUSG00000048652|Ensembl:ENSMUSG00000090202|Vega:OTTMUSG00000033653|Vega:OTTMUSG00000033654 +75016 4930480K23Rik MGI:MGI:1922266|Ensembl:ENSMUSG00000097284 +75017 4930470O06Rik MGI:MGI:1922267|Ensembl:ENSMUSG00000110406 +75018 4930473M17Rik MGI:MGI:1922268 +75019 Rnase10 MGI:MGI:1922269|Ensembl:ENSMUSG00000021872 +75020 4930471E15Rik MGI:MGI:1922270 +75021 4930465K12Rik MGI:MGI:1922271 +75022 4930471L23Rik MGI:MGI:1922272 +75023 4930477J04Rik MGI:MGI:1922273 +75024 4930425L21Rik MGI:MGI:1925379|Ensembl:ENSMUSG00000107396 +75025 4930473O22Rik MGI:MGI:1922275|Ensembl:ENSMUSG00000112484 +75026 4930466F19Rik MGI:MGI:1922276 +75028 4930486I03Rik MGI:MGI:1922278|Ensembl:ENSMUSG00000089914 +75029 Purg MGI:MGI:1922279|Ensembl:ENSMUSG00000049184|Vega:OTTMUSG00000060958 +75030 4930503E24Rik MGI:MGI:1922280|Ensembl:ENSMUSG00000112364 +75032 4930488N15Rik MGI:MGI:1922282 +75033 Mei4 MGI:MGI:1922283|Ensembl:ENSMUSG00000043289|Vega:OTTMUSG00000027459 +75036 4930488B01Rik MGI:MGI:1922286 +75037 4930500G05Rik MGI:MGI:1922287 +75039 Nudt12os MGI:MGI:1922289 +75040 Efcab10 MGI:MGI:1922290|Ensembl:ENSMUSG00000020562 +75043 4930507D10Rik MGI:MGI:1922293|Ensembl:ENSMUSG00000086703 +75044 4930506A18Rik MGI:MGI:1922294 +75045 4930507L24Rik MGI:MGI:1922295 +75047 4930504B16Rik MGI:MGI:1922297 +75048 4930516E23Rik MGI:MGI:1922298 +75049 4930517N10Rik MGI:MGI:1922299 +75050 Kif27 MGI:MGI:1922300|Ensembl:ENSMUSG00000060176 +75051 Ccdc173 MGI:MGI:1923100|Ensembl:ENSMUSG00000070883|Vega:OTTMUSG00000013028 +75052 4930509B17Rik MGI:MGI:1922302 +75053 Kif16bos MGI:MGI:1922303|Ensembl:ENSMUSG00000086504 +75054 4930511P09Rik MGI:MGI:1922304 +75057 4930504B08Rik MGI:MGI:1922307 +75058 4930519H02Rik MGI:MGI:1922308|Ensembl:ENSMUSG00000105185 +75059 4930511C11Rik MGI:MGI:1922309 +75060 4930506C21Rik MGI:MGI:1922310|Ensembl:ENSMUSG00000087478 +75062 Sf3a3 MGI:MGI:1922312|Ensembl:ENSMUSG00000028902|Vega:OTTMUSG00000009168 +75063 4930511M18Rik MGI:MGI:1922313 +75064 Zcchc13 MGI:MGI:1922314|Ensembl:ENSMUSG00000031330|Vega:OTTMUSG00000018343 +75066 4930521E06Rik MGI:MGI:1922316|Ensembl:ENSMUSG00000101701 +75067 4930521O17Rik MGI:MGI:1922317|Ensembl:ENSMUSG00000112899 +75068 4930513N24Rik MGI:MGI:1922318 +75069 4930515L03Rik MGI:MGI:1922319 +75070 4930515G16Rik MGI:MGI:1922320 +75071 4930524N10Rik MGI:MGI:1922321|Ensembl:ENSMUSG00000059663|Vega:OTTMUSG00000019278 +75073 4930505K13Rik MGI:MGI:1922323|Ensembl:ENSMUSG00000109414 +75075 4930517O19Rik MGI:MGI:1922325 +75076 4930504C09Rik MGI:MGI:1922326 +75077 4930509A12Rik MGI:MGI:1922327 +75079 Zbtb49 MGI:MGI:1922329|Ensembl:ENSMUSG00000029127|Vega:OTTMUSG00000023309 +75080 4930518C09Rik MGI:MGI:1922330 +75082 4930519N06Rik MGI:MGI:1922332 +75083 Usp50 MGI:MGI:1922333|Ensembl:ENSMUSG00000027364|Vega:OTTMUSG00000015955 +75084 4930511M06Rik MGI:MGI:1922334|Ensembl:ENSMUSG00000086607 +75085 4930519L02Rik MGI:MGI:1922335 +75086 4930520P13Rik MGI:MGI:1922336|Ensembl:ENSMUSG00000113463 +75087 4930505A04Rik MGI:MGI:1922337|Ensembl:ENSMUSG00000040919|Vega:OTTMUSG00000005342 +75088 4930505G20Rik MGI:MGI:1922338|Ensembl:ENSMUSG00000093551 +75089 Uhrf1bp1l MGI:MGI:2442888|Ensembl:ENSMUSG00000019951 +75090 4930519D14Rik MGI:MGI:1922340|Ensembl:ENSMUSG00000086263 +75091 4930520A20Rik MGI:MGI:1922341 +75094 4930522N08Rik MGI:MGI:1922344 +75095 4930513D17Rik MGI:MGI:1922345|Ensembl:ENSMUSG00000106741 +75096 4930524O05Rik MGI:MGI:1922346 +75097 Ube2dnl2 MGI:MGI:1922347|Ensembl:ENSMUSG00000047079|Vega:OTTMUSG00000018419 +75098 4930515G13Rik MGI:MGI:1922348 +75099 Lysmd4 MGI:MGI:1922349|Ensembl:ENSMUSG00000043831|Vega:OTTMUSG00000059479 +75100 4930525D18Rik MGI:MGI:1922350 +75103 4930518I17Rik MGI:MGI:1922353 +75104 Mmd2 MGI:MGI:1922354|Ensembl:ENSMUSG00000039533|Vega:OTTMUSG00000054880 +75106 4930519F16Rik MGI:MGI:1922356 +75107 4930509H03Rik MGI:MGI:1922357 +75108 4930513N20Rik MGI:MGI:1922358 +75111 4930512H18Rik MGI:MGI:1922361 +75115 4930509E16Rik MGI:MGI:1922365|Ensembl:ENSMUSG00000096986 +75116 4930520O04Rik MGI:MGI:1922366|Ensembl:ENSMUSG00000074039 +75117 4930517M08Rik MGI:MGI:1922367 +75120 4930509E22Rik MGI:MGI:1922370 +75121 4930511O05Rik MGI:MGI:1922371 +75122 Zc2hc1b MGI:MGI:1922372|Ensembl:ENSMUSG00000019815 +75123 4930518J21Rik MGI:MGI:1922373|Ensembl:ENSMUSG00000110310 +75124 Nxnl2 MGI:MGI:1922374|Ensembl:ENSMUSG00000021396 +75125 4930513O06Rik MGI:MGI:1922375|Ensembl:ENSMUSG00000031270|Vega:OTTMUSG00000018718 +75128 4930515B02Rik MGI:MGI:1922378|Ensembl:ENSMUSG00000087045 +75129 4930524J08Rik MGI:MGI:1922379 +75131 4930512J16Rik MGI:MGI:1922381|Ensembl:ENSMUSG00000107622 +75133 4930515L19Rik MGI:MGI:1922383|Ensembl:ENSMUSG00000085157 +75135 4930526I15Rik MGI:MGI:1922385 +75136 Rsph10b MGI:MGI:1922386 +75137 Rprd2 MGI:MGI:1922387|Ensembl:ENSMUSG00000028106|Vega:OTTMUSG00000053034 +75138 4930526L06Rik MGI:MGI:1922388|Ensembl:ENSMUSG00000097091 +75139 Gm38397 MGI:MGI:5618690 +75140 Slxl1 MGI:MGI:1922390|Ensembl:ENSMUSG00000067909|Vega:OTTMUSG00000017407 +75141 Rasd2 MGI:MGI:1922391|Ensembl:ENSMUSG00000034472|Vega:OTTMUSG00000034050 +75145 4930547E14Rik MGI:MGI:1922395 +75146 Mfsd13a MGI:MGI:1922396|Ensembl:ENSMUSG00000025227|Vega:OTTMUSG00000033098 +75148 4930545H06Rik MGI:MGI:1922398|Ensembl:ENSMUSG00000112157 +75149 4930539M17Rik MGI:MGI:1922399|Ensembl:ENSMUSG00000103116 +75150 4930546E12Rik MGI:MGI:1922400 +75151 Ccdc42os MGI:MGI:1922401 +75152 4930540A11Rik MGI:MGI:1922402 +75154 4930542M03Rik MGI:MGI:1922404 +75155 4930529K09Rik MGI:MGI:1922405 +75159 4930533P14Rik MGI:MGI:1922409|Ensembl:ENSMUSG00000100589 +75160 4930543I03Rik MGI:MGI:1922410 +75161 4930544M13Rik MGI:MGI:1922411|Ensembl:ENSMUSG00000051758 +75162 4930545E07Rik MGI:MGI:1922412 +75163 4930542C16Rik MGI:MGI:1922413 +75164 4930527J03Rik MGI:MGI:1922414 +75166 4930533B01Rik MGI:MGI:1922416|Ensembl:ENSMUSG00000084798 +75167 4930527F18Rik MGI:MGI:1922417 +75168 4930533B18Rik MGI:MGI:1922418 +75169 4930534I15Rik MGI:MGI:1922419 +75170 Nrg3os MGI:MGI:1922420|Ensembl:ENSMUSG00000093528 +75172 Ccdc146 MGI:MGI:1922422|Ensembl:ENSMUSG00000064280|Vega:OTTMUSG00000025647 +75173 Tex38 MGI:MGI:1922423|Ensembl:ENSMUSG00000044556|Vega:OTTMUSG00000008687 +75174 4930540E01Rik MGI:MGI:1922424 +75175 4930542C21Rik MGI:MGI:1922425 +75176 4930543D07Rik MGI:MGI:1922426 +75177 4930533D04Rik MGI:MGI:1922427 +75178 Meiob MGI:MGI:1922428|Ensembl:ENSMUSG00000024155 +75180 Tmem269 MGI:MGI:1922430|Ensembl:ENSMUSG00000028642|Vega:OTTMUSG00000008917 +75182 4930532G15Rik MGI:MGI:1922432 +75183 4930535F04Rik MGI:MGI:1922433 +75185 Samt4 MGI:MGI:1922435|Ensembl:ENSMUSG00000025051|Vega:OTTMUSG00000019283 +75187 4930543N07Rik MGI:MGI:1922437|Ensembl:ENSMUSG00000110037 +75188 1700009J07Rik MGI:MGI:1914938|Ensembl:ENSMUSG00000096573 +75189 4930533K18Rik MGI:MGI:1922439 +75190 4930535B17Rik MGI:MGI:1922440 +75191 4930534H03Rik MGI:MGI:1922441 +75193 4930526F13Rik MGI:MGI:1922443 +75194 4930527A07Rik MGI:MGI:1922444 +75195 4930532J02Rik MGI:MGI:1922445 +75196 Ankrd7 MGI:MGI:1922446|Ensembl:ENSMUSG00000029517|Vega:OTTMUSG00000055868 +75197 4930529N20Rik MGI:MGI:1922447|Ensembl:ENSMUSG00000113906 +75198 4930544F09Rik MGI:MGI:1922448 +75199 Rhox2a MGI:MGI:1922449|Ensembl:ENSMUSG00000051827|Vega:OTTMUSG00000017124 +75202 Spaca6 MGI:MGI:1922452|Ensembl:ENSMUSG00000080316|Vega:OTTMUSG00000033432 +75203 4930539N22Rik MGI:MGI:1922453 +75204 Orly MGI:MGI:3716138 +75205 4930533N22Rik MGI:MGI:1922455|Ensembl:ENSMUSG00000108803 +75207 4930533L02Rik MGI:MGI:1922457 +75208 4930539C22Rik MGI:MGI:1922458|Ensembl:ENSMUSG00000105765 +75209 Sv2c MGI:MGI:1922459|Ensembl:ENSMUSG00000051111|Vega:OTTMUSG00000035052 +75210 Prr3 MGI:MGI:1922460|Ensembl:ENSMUSG00000038500|Vega:OTTMUSG00000037219 +75211 4930542D17Rik MGI:MGI:1922461 +75212 Rnf121 MGI:MGI:1922462|Ensembl:ENSMUSG00000070426|Vega:OTTMUSG00000022744 +75213 4930544L20Rik MGI:MGI:1922463 +75216 Cep128 MGI:MGI:1922466|Ensembl:ENSMUSG00000061533|Vega:OTTMUSG00000033550 +75218 4930535E02Rik MGI:MGI:1922468 +75219 Dusp18 MGI:MGI:1922469|Ensembl:ENSMUSG00000047205|Vega:OTTMUSG00000005037 +75220 4930535I16Rik MGI:MGI:1922470 +75221 Dpp3 MGI:MGI:1922471|Ensembl:ENSMUSG00000063904 +75223 4930528D03Rik MGI:MGI:1922473|Ensembl:ENSMUSG00000097502 +75224 4930528J11Rik MGI:MGI:1922474 +75225 4930543I11Rik MGI:MGI:1922475 +75226 4930529F21Rik MGI:MGI:1922476 +75228 4930546B01Rik MGI:MGI:1922478 +75231 4930529I22Rik MGI:MGI:1922481 +75233 4930532M18Rik MGI:MGI:1922483|Ensembl:ENSMUSG00000100221 +75234 Rnf19b MGI:MGI:1922484|Ensembl:ENSMUSG00000028793 +75236 4930526M16Rik MGI:MGI:1922486 +75237 4930535O05Rik MGI:MGI:1922487 +75239 4930543E12Rik MGI:MGI:1922489|Ensembl:ENSMUSG00000110009 +75242 Hmgb4os MGI:MGI:1922492 +75243 4930549C15Rik MGI:MGI:1922493|Ensembl:ENSMUSG00000114048 +75244 4930553I04Rik MGI:MGI:1922494 +75245 4930550C17Rik MGI:MGI:1922495|Ensembl:ENSMUSG00000097361 +75246 4930553M12Rik MGI:MGI:1922496 +75247 4930553E22Rik MGI:MGI:1922497 +75249 4930554P06Rik MGI:MGI:1922499 +75250 4930554D03Rik MGI:MGI:1922500 +75252 4930555G21Rik MGI:MGI:1922502|Ensembl:ENSMUSG00000113329 +75253 4930554C24Rik MGI:MGI:1922503|Ensembl:ENSMUSG00000099724 +75255 4930562F07Rik MGI:MGI:1922505|Ensembl:ENSMUSG00000026729 +75256 4930562F17Rik MGI:MGI:1922506|Ensembl:ENSMUSG00000104014 +75258 4930563M21Rik MGI:MGI:1922508|Ensembl:ENSMUSG00000050702|Vega:OTTMUSG00000063112 +75259 4930556M19Rik MGI:MGI:1922509|Ensembl:ENSMUSG00000097058 +75260 4930562M23Rik MGI:MGI:1922510 +75261 4930551L18Rik MGI:MGI:1922511 +75262 4930550I04Rik MGI:MGI:1922512 +75263 4930551O13Rik MGI:MGI:1922513 +75264 4930553P13Rik MGI:MGI:1922514 +75266 Tomm20l MGI:MGI:1922516|Ensembl:ENSMUSG00000021078 +75268 4930554G03Rik MGI:MGI:1922518 +75269 4930564D02Rik MGI:MGI:1922519|Ensembl:ENSMUSG00000051788|Vega:OTTMUSG00000053156 +75270 4930556I23Rik MGI:MGI:1922520 +75272 Erich6b MGI:MGI:1922522|Ensembl:ENSMUSG00000022002 +75273 Pelp1 MGI:MGI:1922523|Ensembl:ENSMUSG00000018921|Vega:OTTMUSG00000006046 +75274 4930558G05Rik MGI:MGI:1922524|Ensembl:ENSMUSG00000086244 +75275 Tmco5b MGI:MGI:1922525|Ensembl:ENSMUSG00000041255|Vega:OTTMUSG00000015131 +75276 Ppp1r1c MGI:MGI:1923185|Ensembl:ENSMUSG00000034683|Vega:OTTMUSG00000013319 +75277 4930556A20Rik MGI:MGI:1922527 +75278 4930547H16Rik MGI:MGI:1922528 +75279 4930555B11Rik MGI:MGI:1922529|Ensembl:ENSMUSG00000086396 +75280 4930554G24Rik MGI:MGI:1922530|Ensembl:ENSMUSG00000085452 +75281 4930548G14Rik MGI:MGI:1922531|Ensembl:ENSMUSG00000051198 +75282 4930555G07Rik MGI:MGI:1922532 +75283 4930556L07Rik MGI:MGI:1922533 +75284 Bcdin3d MGI:MGI:1922534|Ensembl:ENSMUSG00000037525 +75285 4930556N13Rik MGI:MGI:1922535|Ensembl:ENSMUSG00000092399 +75286 4930549G23Rik MGI:MGI:1922536 +75288 Slc35f4 MGI:MGI:1922538|Ensembl:ENSMUSG00000021852|Vega:OTTMUSG00000032891 +75290 4930557B15Rik MGI:MGI:1922540 +75291 Zbtb3 MGI:MGI:1922541|Ensembl:ENSMUSG00000071661 +75292 Prkd3 MGI:MGI:1922542|Ensembl:ENSMUSG00000024070|Vega:OTTMUSG00000031058 +75295 4930559C10Rik MGI:MGI:1922545|Ensembl:ENSMUSG00000113164 +75296 Fgfr1op MGI:MGI:1922546|Ensembl:ENSMUSG00000069135|Vega:OTTMUSG00000034291 +75297 4930554N03Rik MGI:MGI:1922547 +75299 4930547M16Rik MGI:MGI:1922549 +75300 4930548F15Rik MGI:MGI:1922550 +75301 4930556N09Rik MGI:MGI:1922551|Ensembl:ENSMUSG00000111924 +75302 Asxl2 MGI:MGI:1922552|Ensembl:ENSMUSG00000037486|Vega:OTTMUSG00000022971 +75303 4930562A09Rik MGI:MGI:1922553 +75304 4930563E22Rik MGI:MGI:1922554 +75305 Ankrd53 MGI:MGI:1922555|Ensembl:ENSMUSG00000014747|Vega:OTTMUSG00000058016 +75306 4930557F08Rik MGI:MGI:1922556 +75308 4930557B21Rik MGI:MGI:1922558 +75309 4930565D16Rik MGI:MGI:1922559|Ensembl:ENSMUSG00000104004 +75310 4930556C24Rik MGI:MGI:1922560 +75311 4930550C14Rik MGI:MGI:1922561|Ensembl:ENSMUSG00000005131|Vega:OTTMUSG00000063126 +75313 4930551I15Rik MGI:MGI:1922563 +75314 4930551I23Rik MGI:MGI:1922564 +75315 4930553C11Rik MGI:MGI:1922565 +75316 Taf1d MGI:MGI:1922566|Ensembl:ENSMUSG00000031939|Vega:OTTMUSG00000062264 +75317 Parpbp MGI:MGI:1922567|Ensembl:ENSMUSG00000035365|Vega:OTTMUSG00000035174 +75318 4930547G20Rik MGI:MGI:1922568 +75319 4930555O08Rik MGI:MGI:1922569 +75320 Etnk1 MGI:MGI:1922570|Ensembl:ENSMUSG00000030275|Vega:OTTMUSG00000057145 +75321 Grip1os2 MGI:MGI:1922571|Ensembl:ENSMUSG00000084764 +75322 4930557F10Rik MGI:MGI:1922572|Ensembl:ENSMUSG00000085488 +75323 4930558J18Rik MGI:MGI:1922573|Ensembl:ENSMUSG00000097519 +75324 4930562D21Rik MGI:MGI:1922574 +75326 4930563J15Rik MGI:MGI:1922576 +75328 4930563D23Rik MGI:MGI:1922578|Ensembl:ENSMUSG00000051728|Vega:OTTMUSG00000063067 +75329 Atf7ip2 MGI:MGI:1922579|Ensembl:ENSMUSG00000039200|Vega:OTTMUSG00000027627 +75330 4930558F17Rik MGI:MGI:1922580|Ensembl:ENSMUSG00000106506 +75332 4930556G01Rik MGI:MGI:1922582 +75333 4930556A12Rik MGI:MGI:1922583 +75335 4930549O18Rik MGI:MGI:1922585 +75338 Ccdc83 MGI:MGI:1918255|Ensembl:ENSMUSG00000030617|Vega:OTTMUSG00000022954 +75339 Mphosph8 MGI:MGI:1922589|Ensembl:ENSMUSG00000079184|Vega:OTTMUSG00000017272 +75340 4930554G22Rik MGI:MGI:1922590 +75341 4930564C03Rik MGI:MGI:1922591 +75342 4930556J24Rik MGI:MGI:1922592 +75343 4930557B06Rik MGI:MGI:1922593 +75345 Slamf7 MGI:MGI:1922595|Ensembl:ENSMUSG00000038179|Vega:OTTMUSG00000050083 +75347 4930563H07Rik MGI:MGI:1922597|Ensembl:ENSMUSG00000107656 +75349 4930556J02Rik MGI:MGI:1922599 +75350 4930552F14Rik MGI:MGI:1922600 +75351 4930553J12Rik MGI:MGI:1922601 +75352 4930550L24Rik MGI:MGI:1922602|Ensembl:ENSMUSG00000046180|Vega:OTTMUSG00000019446 +75353 4930553I21Rik MGI:MGI:1922603 +75354 4930554I06Rik MGI:MGI:1922604 +75355 4930553P18Rik MGI:MGI:1922605|Ensembl:ENSMUSG00000106791 +75357 4930557J02Rik MGI:MGI:1922607|Ensembl:ENSMUSG00000106902 +75358 4930554B03Rik MGI:MGI:1922608 +75359 4930555F03Rik MGI:MGI:1922609 +75360 4930548K13Rik MGI:MGI:1922610|Ensembl:ENSMUSG00000086257 +75361 4930555K05Rik MGI:MGI:1922611 +75364 4930549P19Rik MGI:MGI:1922614 +75367 4930552N02Rik MGI:MGI:1922617|Ensembl:ENSMUSG00000089717|Vega:OTTMUSG00000007059 +75368 4930558K02Rik MGI:MGI:1922618|Ensembl:ENSMUSG00000086277|Vega:OTTMUSG00000029467 +75369 4930563F08Rik MGI:MGI:1922619|Ensembl:ENSMUSG00000105773 +75370 4930563E18Rik MGI:MGI:1922620|Ensembl:ENSMUSG00000097387 +75373 4930597O21Rik MGI:MGI:1922623 +75374 4930595O18Rik MGI:MGI:1922624 +75375 4930598N05Rik MGI:MGI:1922625 +75377 4930597G03Rik MGI:MGI:1922627 +75378 4930597G05Rik MGI:MGI:1922628 +75379 4930599N23Rik MGI:MGI:1922629|Ensembl:ENSMUSG00000073144 +75380 4930597E08Rik MGI:MGI:1922630 +75381 4930598F16Rik MGI:MGI:1922631|Ensembl:ENSMUSG00000100777 +75383 4930599N24Rik MGI:MGI:1922633 +75384 Lyzl4os MGI:MGI:1922634|Ensembl:ENSMUSG00000084995 +75385 4930597L12Rik MGI:MGI:1922635 +75386 4930599A14Rik MGI:MGI:1922636 +75387 Sirt4 MGI:MGI:1922637|Ensembl:ENSMUSG00000029524|Vega:OTTMUSG00000014665 +75388 Boll MGI:MGI:1922638|Ensembl:ENSMUSG00000025977|Vega:OTTMUSG00000030118 +75389 4930597A21Rik MGI:MGI:1922639|Ensembl:ENSMUSG00000086501 +75394 0610040F04Rik MGI:MGI:1922644|Ensembl:ENSMUSG00000087341 +75395 Hoxb5os MGI:MGI:1922645|Ensembl:ENSMUSG00000085645 +75396 Spp2 MGI:MGI:1922646|Ensembl:ENSMUSG00000026295|Vega:OTTMUSG00000020812 +75398 Mrpl32 MGI:MGI:2137226|Ensembl:ENSMUSG00000015672 +75399 0610039G09Rik MGI:MGI:1922649 +75400 Defb29 MGI:MGI:1922650|Ensembl:ENSMUSG00000044249|Vega:OTTMUSG00000015857 +75402 0610042B23Rik MGI:MGI:1922652 +75403 1010001B22Rik MGI:MGI:1922653 +75404 Arhgap36 MGI:MGI:1922654|Ensembl:ENSMUSG00000036198|Vega:OTTMUSG00000017740 +75405 1100001I12Rik MGI:MGI:1922655 +75406 Ndufs7 MGI:MGI:1922656|Ensembl:ENSMUSG00000020153|Vega:OTTMUSG00000000012 +75409 Slitrk5 MGI:MGI:2679448|Ensembl:ENSMUSG00000033214 +75410 Kmt2b MGI:MGI:109565|Ensembl:ENSMUSG00000006307|Vega:OTTMUSG00000023938 +75415 Arhgap12 MGI:MGI:1922665|Ensembl:ENSMUSG00000041225|Vega:OTTMUSG00000036618 +75416 Nop14 MGI:MGI:1922666|Ensembl:ENSMUSG00000036693|Vega:OTTMUSG00000023150 +75418 2610034B04Rik MGI:MGI:1922668 +75420 Secisbp2 MGI:MGI:1922670|Ensembl:ENSMUSG00000035139|Vega:OTTMUSG00000020967 +75422 Mettl5 MGI:MGI:1922672|Ensembl:ENSMUSG00000051730|Vega:OTTMUSG00000013041 +75423 Arl5a MGI:MGI:1922673|Ensembl:ENSMUSG00000036093|Vega:OTTMUSG00000012609 +75424 Zfp820 MGI:MGI:1922674|Ensembl:ENSMUSG00000069743 +75425 Tti1 MGI:MGI:1922675|Ensembl:ENSMUSG00000027650|Vega:OTTMUSG00000015889 +75426 Igfbpl1 MGI:MGI:1933198|Ensembl:ENSMUSG00000035551|Vega:OTTMUSG00000006731 +75428 3100002H20Rik MGI:MGI:1922678 +75429 Fam183b MGI:MGI:1922679|Ensembl:ENSMUSG00000049154|Vega:OTTMUSG00000005762 +75430 Anapc15 MGI:MGI:1922680|Ensembl:ENSMUSG00000030649|Vega:OTTMUSG00000025103 +75431 3110001L01Rik MGI:MGI:1922681 +75432 1700006F04Rik MGI:MGI:1922682|Ensembl:ENSMUSG00000100274 +75433 1700001G01Rik MGI:MGI:1922683|Ensembl:ENSMUSG00000087170 +75434 1700001C02Rik MGI:MGI:1922684|Ensembl:ENSMUSG00000029182|Vega:OTTMUSG00000022268 +75437 1700006E09Rik MGI:MGI:1922687|Ensembl:ENSMUSG00000010841|Vega:OTTMUSG00000002319 +75439 Cypt12 MGI:MGI:1922689|Ensembl:ENSMUSG00000027564|Vega:OTTMUSG00000052328 +75440 1700010K24Rik MGI:MGI:1922690 +75442 1700008N11Rik MGI:MGI:1922692 +75443 1700011M02Rik MGI:MGI:1922693|Ensembl:ENSMUSG00000079476|Vega:OTTMUSG00000018185 +75444 1700011I03Rik MGI:MGI:1922694|Ensembl:ENSMUSG00000058925|Vega:OTTMUSG00000033166 +75445 1700008B15Rik MGI:MGI:1922695 +75448 Rsf1os1 MGI:MGI:1922698|Ensembl:ENSMUSG00000086433 +75449 1700008N17Rik MGI:MGI:1922699 +75451 1700011C11Rik MGI:MGI:1922701|Ensembl:ENSMUSG00000108800 +75452 Ascc2 MGI:MGI:1922702|Ensembl:ENSMUSG00000020412|Vega:OTTMUSG00000005066 +75453 Ccdc7b MGI:MGI:1922703|Ensembl:ENSMUSG00000056018|Vega:OTTMUSG00000022627 +75454 Phpt1 MGI:MGI:1922704|Ensembl:ENSMUSG00000036504|Vega:OTTMUSG00000012163 +75456 Prps1l1 MGI:MGI:1922706|Ensembl:ENSMUSG00000092305|Vega:OTTMUSG00000037135 +75458 Cklf MGI:MGI:1922708|Ensembl:ENSMUSG00000054400|Vega:OTTMUSG00000061884 +75459 Syce3 MGI:MGI:1922709|Ensembl:ENSMUSG00000078938|Vega:OTTMUSG00000049834 +75462 1700001C19Rik MGI:MGI:1922712|Ensembl:ENSMUSG00000047150|Vega:OTTMUSG00000028416 +75463 1700008A23Rik MGI:MGI:1922713 +75464 1700011D18Rik MGI:MGI:1922714 +75465 Dynlrb2 MGI:MGI:1922715|Ensembl:ENSMUSG00000034467|Vega:OTTMUSG00000061717 +75467 Stpg4 MGI:MGI:1922717|Ensembl:ENSMUSG00000036557|Vega:OTTMUSG00000045108 +75469 Spata19 MGI:MGI:1922719|Ensembl:ENSMUSG00000031991|Vega:OTTMUSG00000062755 +75470 Iqcf5 MGI:MGI:1922720|Ensembl:ENSMUSG00000066382|Vega:OTTMUSG00000049450 +75471 1700009N14Rik MGI:MGI:1922721|Ensembl:ENSMUSG00000028287|Vega:OTTMUSG00000006545 +75472 Cfap126 MGI:MGI:1922722|Ensembl:ENSMUSG00000026649|Vega:OTTMUSG00000021658 +75475 Oplah MGI:MGI:1922725|Ensembl:ENSMUSG00000022562|Vega:OTTMUSG00000035743 +75476 1700010I02Rik MGI:MGI:1922726|Ensembl:ENSMUSG00000100010 +75477 Pfn3 MGI:MGI:2178800|Ensembl:ENSMUSG00000044444 +75479 1700012D14Rik MGI:MGI:1922729|Ensembl:ENSMUSG00000110424 +75480 1700003F12Rik MGI:MGI:1922730|Ensembl:ENSMUSG00000038523|Vega:OTTMUSG00000015791 +75482 Hspb9 MGI:MGI:1922732|Ensembl:ENSMUSG00000017832|Vega:OTTMUSG00000002057 +75483 Cox8c MGI:MGI:1922733|Ensembl:ENSMUSG00000043319 +75484 1700007H22Rik MGI:MGI:1922734 +75485 1700010B08Rik MGI:MGI:1922735|Ensembl:ENSMUSG00000057047|Vega:OTTMUSG00000016373 +75487 1700012J15Rik MGI:MGI:1922737 +75488 1700012O15Rik MGI:MGI:1922738 +75489 1700012D16Rik MGI:MGI:1922739|Ensembl:ENSMUSG00000105023 +75493 1700003L19Rik MGI:MGI:1922743|Ensembl:ENSMUSG00000101565 +75494 1700008C04Rik MGI:MGI:1922744|Ensembl:ENSMUSG00000111986 +75495 Morn5 MGI:MGI:1922745|Ensembl:ENSMUSG00000026894|Vega:OTTMUSG00000012101 +75496 1700012J22Rik MGI:MGI:1922746 +75497 Fabp12 MGI:MGI:1922747|Ensembl:ENSMUSG00000027530|Vega:OTTMUSG00000027699 +75498 1700008A07Rik MGI:MGI:1922748 +75500 1700010H22Rik MGI:MGI:1922750 +75501 1700010K23Rik MGI:MGI:1922751|Ensembl:ENSMUSG00000092599 +75502 Cmtm2b MGI:MGI:2447311|Ensembl:ENSMUSG00000035785|Vega:OTTMUSG00000061904 +75504 1700013F07Rik MGI:MGI:1922754|Ensembl:ENSMUSG00000027886|Vega:OTTMUSG00000007253 +75505 1700013M08Rik MGI:MGI:1922755 +75506 1700017I07Rik MGI:MGI:1922756 +75507 Pou5f2 MGI:MGI:1922757|Ensembl:ENSMUSG00000093668|Vega:OTTMUSG00000039919 +75508 1700017J07Rik MGI:MGI:1922758|Ensembl:ENSMUSG00000086348 +75509 1700020N15Rik MGI:MGI:1922759|Ensembl:ENSMUSG00000059690|Vega:OTTMUSG00000017708 +75510 Izumo2 MGI:MGI:1922760|Ensembl:ENSMUSG00000066500|Vega:OTTMUSG00000058705 +75512 Gpx6 MGI:MGI:1922762|Ensembl:ENSMUSG00000004341|Vega:OTTMUSG00000000419 +75514 1700013H16Rik MGI:MGI:1922764|Ensembl:ENSMUSG00000054727|Vega:OTTMUSG00000017387 +75516 Ttc32 MGI:MGI:1922766|Ensembl:ENSMUSG00000066637 +75517 Ccdc34os MGI:MGI:1922767|Ensembl:ENSMUSG00000086186 +75519 1700021F02Rik MGI:MGI:1922769|Ensembl:ENSMUSG00000105426 +75520 1700024N05Rik MGI:MGI:1922770 +75521 1700021P04Rik MGI:MGI:1922771 +75522 1700024I08Rik MGI:MGI:1922772|Ensembl:ENSMUSG00000113825 +75524 Tex48 MGI:MGI:1922774|Ensembl:ENSMUSG00000058935|Vega:OTTMUSG00000000251 +75525 1700024K11Rik MGI:MGI:1922775 +75526 Eppin MGI:MGI:1922776|Ensembl:ENSMUSG00000017733|Vega:OTTMUSG00000001094 +75527 1700015H07Rik MGI:MGI:1922777 +75528 Tex29 MGI:MGI:1922778|Ensembl:ENSMUSG00000031512|Vega:OTTMUSG00000027106 +75530 Lyrm7 MGI:MGI:1922780|Ensembl:ENSMUSG00000020268|Vega:OTTMUSG00000005675 +75531 1700025H01Rik MGI:MGI:1922781 +75532 1700015C15Rik MGI:MGI:1922782 +75533 Nme5 MGI:MGI:1922783|Ensembl:ENSMUSG00000035984|Vega:OTTMUSG00000033174 +75534 1700015I17Rik MGI:MGI:1922784 +75535 1700016D02Rik MGI:MGI:1922785 +75536 Clnkos MGI:MGI:1922786 +75538 Fam71e1 MGI:MGI:1922788|Ensembl:ENSMUSG00000051113|Vega:OTTMUSG00000058328 +75539 1700022H01Rik MGI:MGI:1922789 +75540 Fpgt MGI:MGI:1922790|Ensembl:ENSMUSG00000053870|Vega:OTTMUSG00000052247 +75541 Nat8f4 MGI:MGI:1922791|Ensembl:ENSMUSG00000068299|Vega:OTTMUSG00000034544 +75543 1700019C18Rik MGI:MGI:1922793|Ensembl:ENSMUSG00000113770 +75544 1700016K05Rik MGI:MGI:1922794 +75545 1700019B21Rik MGI:MGI:1922795|Ensembl:ENSMUSG00000085757 +75546 1700019P21Rik MGI:MGI:1922796|Ensembl:ENSMUSG00000099808 +75547 Akap13 MGI:MGI:2676556|Ensembl:ENSMUSG00000066406|Vega:OTTMUSG00000034140 +75549 1700019L22Rik MGI:MGI:1922799 +75552 Paqr9 MGI:MGI:1922802|Ensembl:ENSMUSG00000064225|Vega:OTTMUSG00000022621 +75553 Zc3h14 MGI:MGI:1919824|Ensembl:ENSMUSG00000021012 +75554 1700020K04Rik MGI:MGI:1922804 +75555 1700020D05Rik MGI:MGI:1922805|Ensembl:ENSMUSG00000100937|Vega:OTTMUSG00000045127 +75556 Cfap161 MGI:MGI:1922806|Ensembl:ENSMUSG00000011154|Vega:OTTMUSG00000027328 +75558 Spata45 MGI:MGI:1922808|Ensembl:ENSMUSG00000057072|Vega:OTTMUSG00000051394 +75560 Ep400 MGI:MGI:1276124|Ensembl:ENSMUSG00000029505|Vega:OTTMUSG00000017135 +75561 1700016J18Rik MGI:MGI:1922811 +75563 Dnali1 MGI:MGI:1922813|Ensembl:ENSMUSG00000042707|Vega:OTTMUSG00000009247 +75564 Rsph9 MGI:MGI:1922814|Ensembl:ENSMUSG00000023966|Vega:OTTMUSG00000028346 +75565 Sgf29 MGI:MGI:1922815|Ensembl:ENSMUSG00000030714|Vega:OTTMUSG00000025253 +75567 1700027I24Rik MGI:MGI:1922817|Ensembl:ENSMUSG00000098304 +75568 Capsl MGI:MGI:1922818|Ensembl:ENSMUSG00000039676 +75569 1700028D13Rik MGI:MGI:1922819|Ensembl:ENSMUSG00000101683 +75570 Nhej1 MGI:MGI:1922820|Ensembl:ENSMUSG00000026162|Vega:OTTMUSG00000021757 +75571 Spata9 MGI:MGI:1922821|Ensembl:ENSMUSG00000021590 +75572 Acyp2 MGI:MGI:1922822|Ensembl:ENSMUSG00000060923|Vega:OTTMUSG00000005346 +75573 Prr29 MGI:MGI:1922823|Ensembl:ENSMUSG00000009210|Vega:OTTMUSG00000003422 +75576 1700030L22Rik MGI:MGI:1922826 +75577 Dynap MGI:MGI:1922827|Ensembl:ENSMUSG00000024512 +75578 Fggy MGI:MGI:1922828|Ensembl:ENSMUSG00000028573|Vega:OTTMUSG00000008049 +75579 2310034G01Rik MGI:MGI:1922829 +75580 Zbtb4 MGI:MGI:1922830|Ensembl:ENSMUSG00000018750|Vega:OTTMUSG00000005990 +75581 Yipf7 MGI:MGI:1922831|Ensembl:ENSMUSG00000029158|Vega:OTTMUSG00000022940 +75584 2310030A07Rik MGI:MGI:1922834|Ensembl:ENSMUSG00000099447 +75586 Krtap9-3 MGI:MGI:1922836|Ensembl:ENSMUSG00000049809|Vega:OTTMUSG00000004965 +75588 2310074N15Rik MGI:MGI:1922838 +75589 2310043L19Rik MGI:MGI:1922839|Ensembl:ENSMUSG00000101746 +75590 Dusp9 MGI:MGI:2387107|Ensembl:ENSMUSG00000031383|Vega:OTTMUSG00000017648 +75593 Malsu1 MGI:MGI:1922843|Ensembl:ENSMUSG00000029815|Vega:OTTMUSG00000024395 +75596 Prl7b1 MGI:MGI:1922846|Ensembl:ENSMUSG00000021347|Vega:OTTMUSG00000000646 +75597 Ndufaf2 MGI:MGI:1922847|Ensembl:ENSMUSG00000068184 +75599 Pcdh1 MGI:MGI:104692|Ensembl:ENSMUSG00000051375|Vega:OTTMUSG00000033463 +75600 Calml4 MGI:MGI:1922850|Ensembl:ENSMUSG00000032246|Vega:OTTMUSG00000062566 +75601 1810049I09Rik MGI:MGI:1922851|Ensembl:ENSMUSG00000108587 +75602 1810062O18Rik MGI:MGI:1922852|Ensembl:ENSMUSG00000084925 +75604 Tm4sf5 MGI:MGI:1922854|Ensembl:ENSMUSG00000018919|Vega:OTTMUSG00000006052 +75605 Kdm5b MGI:MGI:1922855|Ensembl:ENSMUSG00000042207|Vega:OTTMUSG00000017092 +75607 Wnk2 MGI:MGI:1922857|Ensembl:ENSMUSG00000037989|Vega:OTTMUSG00000035035 +75608 Chmp4b MGI:MGI:1922858|Ensembl:ENSMUSG00000038467|Vega:OTTMUSG00000015914 +75610 2010109A12Rik MGI:MGI:1922860|Ensembl:ENSMUSG00000029384|Vega:OTTMUSG00000026617 +75612 Gns MGI:MGI:1922862|Ensembl:ENSMUSG00000034707 +75613 Med25 MGI:MGI:1922863|Ensembl:ENSMUSG00000002968|Vega:OTTMUSG00000058334 +75614 Rab26os MGI:MGI:1922864|Ensembl:ENSMUSG00000093565 +75616 Smim15 MGI:MGI:1922866|Ensembl:ENSMUSG00000071180 +75617 Rps25 MGI:MGI:1922867|Ensembl:ENSMUSG00000009927|Vega:OTTMUSG00000063299 +75619 Fastkd2 MGI:MGI:1922869|Ensembl:ENSMUSG00000025962|Vega:OTTMUSG00000013921 +75620 Kxd1 MGI:MGI:1922870|Ensembl:ENSMUSG00000055553|Vega:OTTMUSG00000031162 +75622 Spaca3 MGI:MGI:1922872|Ensembl:ENSMUSG00000053184|Vega:OTTMUSG00000000851 +75623 Tex30 MGI:MGI:1922873|Ensembl:ENSMUSG00000026049|Vega:OTTMUSG00000034051 +75624 Metap1 MGI:MGI:1922874|Ensembl:ENSMUSG00000005813|Vega:OTTMUSG00000052836 +75625 Mageh1 MGI:MGI:1922875|Ensembl:ENSMUSG00000047238|Vega:OTTMUSG00000019340 +75627 Snapc1 MGI:MGI:1922877|Ensembl:ENSMUSG00000021113 +75628 1700010L13Rik MGI:MGI:1922878 +75629 Thap8 MGI:MGI:1922879 +75630 1700020G17Rik MGI:MGI:1922880|Ensembl:ENSMUSG00000101801 +75631 1700008F19Rik MGI:MGI:1922881 +75632 1700003O11Rik MGI:MGI:1922882 +75633 1700007A02Rik MGI:MGI:1922883 +75634 1700013N06Rik MGI:MGI:1922884 +75636 1700022E09Rik MGI:MGI:1922886|Ensembl:ENSMUSG00000099983 +75637 1700020L05Rik MGI:MGI:1922887 +75638 1700008O09Rik MGI:MGI:1922888 +75639 1700018H16Rik MGI:MGI:1922889 +75640 1700016B01Rik MGI:MGI:1922890|Ensembl:ENSMUSG00000104538 +75641 1700029I15Rik MGI:MGI:1916742|Ensembl:ENSMUSG00000044916|Vega:OTTMUSG00000014472 +75642 Spata25 MGI:MGI:1922892|Ensembl:ENSMUSG00000017767|Vega:OTTMUSG00000001108 +75645 Ccdc172 MGI:MGI:1922895|Ensembl:ENSMUSG00000025090 +75646 Rai14 MGI:MGI:1922896|Ensembl:ENSMUSG00000022246 +75647 Ssmem1 MGI:MGI:1922897|Ensembl:ENSMUSG00000029784|Vega:OTTMUSG00000014379 +75649 1700016L15Rik MGI:MGI:1922899 +75653 1700016H03Rik MGI:MGI:1922903 +75654 1700003O08Rik MGI:MGI:1922904 +75655 1700028P15Rik MGI:MGI:1922905|Ensembl:ENSMUSG00000086823 +75656 1700020A23Rik MGI:MGI:1922906|Ensembl:ENSMUSG00000027409|Vega:OTTMUSG00000015504 +75657 Speer4a MGI:MGI:1922907|Ensembl:ENSMUSG00000073119|Vega:OTTMUSG00000036610 +75659 Wdr54 MGI:MGI:1922909|Ensembl:ENSMUSG00000030032|Vega:OTTMUSG00000026966 +75660 Lin37 MGI:MGI:1922910|Ensembl:ENSMUSG00000036845|Vega:OTTMUSG00000026206 +75662 1700030C14Rik MGI:MGI:1922912|Ensembl:ENSMUSG00000087148 +75665 Bicdl1 MGI:MGI:1922915|Ensembl:ENSMUSG00000041609|Vega:OTTMUSG00000014707 +75667 Tmem225 MGI:MGI:1922917|Ensembl:ENSMUSG00000040541 +75668 Rasl10a MGI:MGI:1922918|Ensembl:ENSMUSG00000034209|Vega:OTTMUSG00000005072 +75669 Pik3r4 MGI:MGI:1922919|Ensembl:ENSMUSG00000032571|Vega:OTTMUSG00000049417 +75671 Tex22 MGI:MGI:1922921|Ensembl:ENSMUSG00000012211|Vega:OTTMUSG00000033958 +75677 Cldn22 MGI:MGI:1922927|Ensembl:ENSMUSG00000038064|Vega:OTTMUSG00000061830 +75678 Ippk MGI:MGI:1922928|Ensembl:ENSMUSG00000021385 +75680 2310007H06Rik MGI:MGI:1922930 +75681 2310041K03Rik MGI:MGI:1922931 +75683 2310035P21Rik MGI:MGI:1922933 +75686 Nudt16 MGI:MGI:1922936|Ensembl:ENSMUSG00000032565|Vega:OTTMUSG00000045306 +75687 Ripor1 MGI:MGI:1922937|Ensembl:ENSMUSG00000038604|Vega:OTTMUSG00000062051 +75689 Higd1b MGI:MGI:1922939|Ensembl:ENSMUSG00000020928|Vega:OTTMUSG00000003001 +75690 Vsig10l MGI:MGI:1922940|Ensembl:ENSMUSG00000070604|Vega:OTTMUSG00000022070 +75691 Anks6 MGI:MGI:1922941|Ensembl:ENSMUSG00000066191|Vega:OTTMUSG00000006773 +75692 Nr2c2ap MGI:MGI:1922942|Ensembl:ENSMUSG00000071078|Vega:OTTMUSG00000062216 +75693 3010001F23Rik MGI:MGI:1922943|Ensembl:ENSMUSG00000084885 +75694 2310058D17Rik MGI:MGI:1922944 +75695 Rilpl1 MGI:MGI:1922945|Ensembl:ENSMUSG00000029392|Vega:OTTMUSG00000054874 +75697 C2cd4b MGI:MGI:1922947|Ensembl:ENSMUSG00000091956|Vega:OTTMUSG00000045526 +75698 Fam35a MGI:MGI:1922948|Ensembl:ENSMUSG00000041471 +75704 Ces1h MGI:MGI:1922954|Ensembl:ENSMUSG00000074156|Vega:OTTMUSG00000033579 +75705 Eif4b MGI:MGI:95304|Ensembl:ENSMUSG00000058655 +75706 Krt24 MGI:MGI:1922956|Ensembl:ENSMUSG00000020913|Vega:OTTMUSG00000006445 +75710 Rbm12 MGI:MGI:1922960|Ensembl:ENSMUSG00000089824|Vega:OTTMUSG00000016088 +75712 Tmem14a MGI:MGI:1922962|Ensembl:ENSMUSG00000025933|Vega:OTTMUSG00000029833 +75717 Cul5 MGI:MGI:1922967|Ensembl:ENSMUSG00000032030|Vega:OTTMUSG00000030717 +75718 Vwa5b1 MGI:MGI:1922968|Ensembl:ENSMUSG00000028753|Vega:OTTMUSG00000010001 +75721 4932414N04Rik MGI:MGI:1922971|Ensembl:ENSMUSG00000079324|Vega:OTTMUSG00000012911 +75722 4932412D23Rik MGI:MGI:1922972|Ensembl:ENSMUSG00000075070 +75723 Amotl1 MGI:MGI:1922973|Ensembl:ENSMUSG00000013076|Vega:OTTMUSG00000034188 +75725 Phf14 MGI:MGI:1923539|Ensembl:ENSMUSG00000029629|Vega:OTTMUSG00000017311 +75726 4933407A17Rik MGI:MGI:1922976 +75727 4933415A04Rik MGI:MGI:1922977 +75729 Fam227a MGI:MGI:1922979|Ensembl:ENSMUSG00000042564|Vega:OTTMUSG00000046533 +75731 Idnk MGI:MGI:1922981|Ensembl:ENSMUSG00000050002 +75732 Iqcd MGI:MGI:1922982|Ensembl:ENSMUSG00000029601|Vega:OTTMUSG00000025341 +75734 Mff MGI:MGI:1922984|Ensembl:ENSMUSG00000026150|Vega:OTTMUSG00000034764 +75735 Pank1 MGI:MGI:1922985|Ensembl:ENSMUSG00000033610 +75736 Bcl2l12 MGI:MGI:1922986|Ensembl:ENSMUSG00000003190|Vega:OTTMUSG00000023474 +75738 Cpeb1os1 MGI:MGI:1922988 +75739 Mpp7 MGI:MGI:1922989|Ensembl:ENSMUSG00000057440 +75740 Egfem1 MGI:MGI:1922990|Ensembl:ENSMUSG00000063600|Vega:OTTMUSG00000030000 +75742 6820402A03Rik MGI:MGI:1922992 +75744 Svip MGI:MGI:1922994|Ensembl:ENSMUSG00000074093|Vega:OTTMUSG00000059018 +75745 Rian MGI:MGI:1922995 +75746 Morc4 MGI:MGI:1922996|Ensembl:ENSMUSG00000031434|Vega:OTTMUSG00000018730 +75747 Sesn3 MGI:MGI:1922997|Ensembl:ENSMUSG00000032009|Vega:OTTMUSG00000021054 +75750 Slc10a6 MGI:MGI:1923000|Ensembl:ENSMUSG00000029321|Vega:OTTMUSG00000026717 +75751 Ipo4 MGI:MGI:1923001|Ensembl:ENSMUSG00000002319|Vega:OTTMUSG00000027877 +75753 Klf17 MGI:MGI:2181068|Ensembl:ENSMUSG00000048626|Vega:OTTMUSG00000008648 +75754 9030607L02Rik MGI:MGI:1923004 +75755 9030420N05Rik MGI:MGI:1923005 +75758 9130401M01Rik MGI:MGI:1923008|Ensembl:ENSMUSG00000101892|Vega:OTTMUSG00000049461 +75759 9130011L11Rik MGI:MGI:1923009 +75761 Apol7a MGI:MGI:1923011|Ensembl:ENSMUSG00000010601|Vega:OTTMUSG00000042028 +75763 Dcaf17 MGI:MGI:1923013|Ensembl:ENSMUSG00000041966|Vega:OTTMUSG00000013153 +75764 Slx1b MGI:MGI:1915220|Ensembl:ENSMUSG00000059772|Vega:OTTMUSG00000023277 +75766 Dcstamp MGI:MGI:1923016|Ensembl:ENSMUSG00000022303 +75767 Rab11fip1 MGI:MGI:1923017|Ensembl:ENSMUSG00000031488|Vega:OTTMUSG00000060990 +75768 4833422M21Rik MGI:MGI:1923018|Ensembl:ENSMUSG00000097619 +75769 Plppr5 MGI:MGI:1923019|Ensembl:ENSMUSG00000033342|Vega:OTTMUSG00000026606 +75770 Brsk2 MGI:MGI:1923020|Ensembl:ENSMUSG00000053046|Vega:OTTMUSG00000036942 +75771 LOC75771 - +75772 Pnpla5 MGI:MGI:1923022|Ensembl:ENSMUSG00000018868 +75773 Adad2 MGI:MGI:1923023|Ensembl:ENSMUSG00000024266|Vega:OTTMUSG00000061641 +75774 4930403L11Rik MGI:MGI:1923024 +75775 4930402K13Rik MGI:MGI:1923025|Ensembl:ENSMUSG00000045797|Vega:OTTMUSG00000016865 +75777 Ttc23l MGI:MGI:1923027|Ensembl:ENSMUSG00000022249|Vega:OTTMUSG00000035618 +75778 Them4 MGI:MGI:1923028|Ensembl:ENSMUSG00000028145|Vega:OTTMUSG00000029592 +75781 4930422C21Rik MGI:MGI:1923031 +75782 Lca5 MGI:MGI:1923032|Ensembl:ENSMUSG00000032258|Vega:OTTMUSG00000016496 +75783 4930431F12Rik MGI:MGI:1923033|Ensembl:ENSMUSG00000062496 +75784 1700007G11Rik MGI:MGI:1916571|Ensembl:ENSMUSG00000057816|Vega:OTTMUSG00000053548 +75785 Klhl24 MGI:MGI:1923035|Ensembl:ENSMUSG00000062901 +75786 Ckap5 MGI:MGI:1923036|Ensembl:ENSMUSG00000040549|Vega:OTTMUSG00000014251 +75787 4930471M09Rik MGI:MGI:1922150|Ensembl:ENSMUSG00000097693 +75788 Smurf1 MGI:MGI:1923038|Ensembl:ENSMUSG00000038780|Vega:OTTMUSG00000021547 +75789 4930444M15Rik MGI:MGI:1923039|Ensembl:ENSMUSG00000097172 +75793 4933432K03Rik MGI:MGI:1918562 +75794 4930444K16Rik MGI:MGI:1923044 +75795 4930455D15Rik MGI:MGI:1923045|Ensembl:ENSMUSG00000097553 +75796 Cdyl2 MGI:MGI:1923046|Ensembl:ENSMUSG00000031758|Vega:OTTMUSG00000061718 +75797 4930435N07Rik MGI:MGI:1923047 +75799 4930444P10Rik MGI:MGI:1923049|Ensembl:ENSMUSG00000067795|Vega:OTTMUSG00000022165 +75800 4930442E04Rik MGI:MGI:1923050 +75801 4930447C04Rik MGI:MGI:1923051|Ensembl:ENSMUSG00000021098|Vega:OTTMUSG00000032630 +75802 4930458D05Rik MGI:MGI:1923052 +75804 4930463O16Rik MGI:MGI:1923054|Ensembl:ENSMUSG00000020033 +75805 Nln MGI:MGI:1923055|Ensembl:ENSMUSG00000021710 +75807 4930470B04Rik MGI:MGI:1923057 +75808 4930485G23Rik MGI:MGI:1923058 +75809 4930488L21Rik MGI:MGI:1923059 +75811 Saxo1 MGI:MGI:1923061|Ensembl:ENSMUSG00000028492|Vega:OTTMUSG00000007450 +75812 Tasp1 MGI:MGI:1923062|Ensembl:ENSMUSG00000039033|Vega:OTTMUSG00000015577 +75813 4930484H19Rik MGI:MGI:1923063|Ensembl:ENSMUSG00000112832 +75814 4930467D21Rik MGI:MGI:1923064 +75815 4930470H14Rik MGI:MGI:1923065 +75816 4930466I24Rik MGI:MGI:1923066 +75818 4930478L05Rik MGI:MGI:1923068 +75819 4930509K18Rik MGI:MGI:1923069|Ensembl:ENSMUSG00000087137 +75820 Wdr64 MGI:MGI:1923070|Ensembl:ENSMUSG00000026523|Vega:OTTMUSG00000050252 +75822 4930524C18Rik MGI:MGI:1923072 +75823 Fam227b MGI:MGI:1923073|Ensembl:ENSMUSG00000027209|Vega:OTTMUSG00000015343 +75825 4930537H20Rik MGI:MGI:1923075 +75826 Senp2 MGI:MGI:1923076|Ensembl:ENSMUSG00000022855 +75827 4930542N06Rik MGI:MGI:1923077 +75828 Hormad2 MGI:MGI:1923078|Ensembl:ENSMUSG00000020419|Vega:OTTMUSG00000005064 +75829 Prame MGI:MGI:1923079|Ensembl:ENSMUSG00000031411|Vega:OTTMUSG00000018772 +75830 4930544L18Rik MGI:MGI:1923080 +75831 4930528G23Rik MGI:MGI:1923081|Ensembl:ENSMUSG00000084909 +75833 4930532I03Rik MGI:MGI:1923083|Ensembl:ENSMUSG00000112201 +75835 Vmn2r-ps54 MGI:MGI:1351350|Ensembl:ENSMUSG00000074164 +75836 Atxn7l1os2 MGI:MGI:1923086|Ensembl:ENSMUSG00000085664 +75838 4930560O18Rik MGI:MGI:1923088 +75840 4930558N01Rik MGI:MGI:1923090 +75841 Rnf139 MGI:MGI:1923091|Ensembl:ENSMUSG00000037075 +75842 4930556H04Rik MGI:MGI:1923092 +75843 4930564B12Rik MGI:MGI:1923093 +75844 4930566F21Rik MGI:MGI:1923094 +75845 4930567K12Rik MGI:MGI:1923095|Ensembl:ENSMUSG00000109382 +75847 Ispd MGI:MGI:1923097|Ensembl:ENSMUSG00000043153 +75848 4930566K23Rik MGI:MGI:1923098 +75852 4930590L14Rik MGI:MGI:1923102 +75853 4930592I03Rik MGI:MGI:1923103 +75854 4930579J19Rik MGI:MGI:1923104 +75855 4930579H20Rik MGI:MGI:1923105|Ensembl:ENSMUSG00000101636 +75856 4930580E04Rik MGI:MGI:1923106 +75857 4930568G15Rik MGI:MGI:1923107|Ensembl:ENSMUSG00000102408 +75858 Speer4cos MGI:MGI:1923108|Ensembl:ENSMUSG00000089871 +75859 4930568D16Rik MGI:MGI:1923109|Ensembl:ENSMUSG00000026882|Vega:OTTMUSG00000012256 +75860 Tex26 MGI:MGI:1923110|Ensembl:ENSMUSG00000029660|Vega:OTTMUSG00000055463 +75861 4930571K23Rik MGI:MGI:1923111 +75862 4930572O13Rik MGI:MGI:1923112 +75863 Clec4g MGI:MGI:1923113|Ensembl:ENSMUSG00000074491|Vega:OTTMUSG00000022398 +75864 4930573G07Rik MGI:MGI:1923114 +75867 4930507A01Rik MGI:MGI:1921960 +75868 4930588A03Rik MGI:MGI:1923118 +75869 Arl5b MGI:MGI:1923119|Ensembl:ENSMUSG00000017418|Vega:OTTMUSG00000011387 +75870 Tcam1 MGI:MGI:1923120|Ensembl:ENSMUSG00000020712|Vega:OTTMUSG00000003416 +75871 Zfp821 MGI:MGI:1923121|Ensembl:ENSMUSG00000031728|Vega:OTTMUSG00000061922 +75872 4930568E02Rik MGI:MGI:1923122 +75873 4930568B11Rik MGI:MGI:1923123 +75874 4930590G02Rik MGI:MGI:1923124 +75876 4930579O11Rik MGI:MGI:1923126 +75877 4930591E09Rik MGI:MGI:1923127|Ensembl:ENSMUSG00000111234 +75878 4930579P08Rik MGI:MGI:1923128|Ensembl:ENSMUSG00000112924 +75879 4930589L23Rik MGI:MGI:1923129 +75880 4930592A05Rik MGI:MGI:1923130 +75881 4930579K19Rik MGI:MGI:1923131|Ensembl:ENSMUSG00000051074 +75883 4930568A12Rik MGI:MGI:1923133|Ensembl:ENSMUSG00000101223 +75884 4930572J10Rik MGI:MGI:1923134 +75885 4930566K11Rik MGI:MGI:1923135 +75886 Gstt4 MGI:MGI:1923136|Ensembl:ENSMUSG00000009093|Vega:OTTMUSG00000027939 +75887 4930586N03Rik MGI:MGI:1923137|Ensembl:ENSMUSG00000087097 +75888 4930573H18Rik MGI:MGI:1923138|Ensembl:ENSMUSG00000104766 +75890 1700003P14Rik MGI:MGI:1916594|Ensembl:ENSMUSG00000100727 +75892 4930578I07Rik MGI:MGI:1923142 +75893 4930587E11Rik MGI:MGI:1923143|Ensembl:ENSMUSG00000107563 +75894 Adal MGI:MGI:1923144|Ensembl:ENSMUSG00000027259|Vega:OTTMUSG00000015974 +75896 4930587A21Rik MGI:MGI:1923146 +75900 4930566D17Rik MGI:MGI:1923150 +75901 Dcp1a MGI:MGI:1923151|Ensembl:ENSMUSG00000021962 +75902 4930568A13Rik MGI:MGI:1923152 +75903 4930579M01Rik MGI:MGI:1923153 +75904 4930579D09Rik MGI:MGI:1923154|Ensembl:ENSMUSG00000084971 +75905 4930578C19Rik MGI:MGI:1923155|Ensembl:ENSMUSG00000037358|Vega:OTTMUSG00000017027 +75906 Fam184a MGI:MGI:1923156|Ensembl:ENSMUSG00000019856|Vega:OTTMUSG00000036555 +75909 Vmp1 MGI:MGI:1923159|Ensembl:ENSMUSG00000018171|Vega:OTTMUSG00000001205 +75910 4930590L20Rik MGI:MGI:1923160|Ensembl:ENSMUSG00000102368 +75912 4930572P05Rik MGI:MGI:1923162 +75913 4930579G18Rik MGI:MGI:1923163 +75914 Exoc6b MGI:MGI:1923164|Ensembl:ENSMUSG00000033769|Vega:OTTMUSG00000034535 +75915 Bloc1s6os MGI:MGI:1923165 +75916 4930572K03Rik MGI:MGI:1923166|Ensembl:ENSMUSG00000105308 +75917 4930572C08Rik MGI:MGI:1923167 +75918 4930586H24Rik MGI:MGI:1923168 +75919 4930584E12Rik MGI:MGI:1923169 +75920 4930588G17Rik MGI:MGI:1923170 +75921 4930578M07Rik MGI:MGI:1923171 +75924 4930566N20Rik MGI:MGI:1923174 +75927 Pitpnm2os1 MGI:MGI:1923177|Ensembl:ENSMUSG00000090220 +75929 4930578L24Rik MGI:MGI:1923179 +75930 4930567H12Rik MGI:MGI:1923181|Ensembl:ENSMUSG00000110629 +75932 4930590H14Rik MGI:MGI:1923182 +75934 4930579D07Rik MGI:MGI:1923184 +75937 4930594M17Rik MGI:MGI:1923187 +75938 4930570E01Rik MGI:MGI:1923188 +75939 4930579G24Rik MGI:MGI:1923189|Ensembl:ENSMUSG00000027811|Vega:OTTMUSG00000029418 +75941 4930570B17Rik MGI:MGI:1923191 +75942 4930584F24Rik MGI:MGI:1923192|Ensembl:ENSMUSG00000029044 +75943 4930572G02Rik MGI:MGI:1923193 +75946 4930583P06Rik MGI:MGI:1923196|Ensembl:ENSMUSG00000086954 +75947 4930594O21Rik MGI:MGI:1923197|Ensembl:ENSMUSG00000085677 +75949 4930573C15Rik MGI:MGI:1923199 +75950 4930594A02Rik MGI:MGI:1923200 +75951 4930578M01Rik MGI:MGI:1923201|Ensembl:ENSMUSG00000097587 +75952 4930578G10Rik MGI:MGI:1923202 +75953 Samd7 MGI:MGI:1923203|Ensembl:ENSMUSG00000051860|Vega:OTTMUSG00000038083 +75954 5033403H07Rik MGI:MGI:1923204|Ensembl:ENSMUSG00000106352 +75956 Srrm2 MGI:MGI:1923206|Ensembl:ENSMUSG00000039218|Vega:OTTMUSG00000049491 +75957 Mir17hg MGI:MGI:1923207 +75958 5033403F01Rik MGI:MGI:1923208|Ensembl:ENSMUSG00000096932 +75961 5033418A18Rik MGI:MGI:1923211 +75964 Trappc8 MGI:MGI:2443008|Ensembl:ENSMUSG00000033382 +75965 Zdhhc20 MGI:MGI:1923215|Ensembl:ENSMUSG00000021969 +75972 5033423O07Rik MGI:MGI:1923222 +75973 Ccdc162 MGI:MGI:1923223|Ensembl:ENSMUSG00000075225|Vega:OTTMUSG00000034216 +75974 Dock11 MGI:MGI:1923224|Ensembl:ENSMUSG00000031093|Vega:OTTMUSG00000017193 +75975 5033424D13Rik MGI:MGI:1923225 +75982 5033415L01Rik MGI:MGI:1923232 +75983 5033423K11Rik MGI:MGI:1923233 +75984 5031415H12Rik MGI:MGI:1923234 +75985 Rab30 MGI:MGI:1923235|Ensembl:ENSMUSG00000030643|Vega:OTTMUSG00000022521 +75986 Agmat MGI:MGI:1923236|Ensembl:ENSMUSG00000040706|Vega:OTTMUSG00000009931 +75990 5033421B08Rik MGI:MGI:1923240 +75991 Slain2 MGI:MGI:1923241|Ensembl:ENSMUSG00000036087|Vega:OTTMUSG00000033878 +75995 5033417F24Rik MGI:MGI:1923245|Ensembl:ENSMUSG00000097251 +75996 5033428I22Rik MGI:MGI:1923246|Ensembl:ENSMUSG00000097910 +75998 5033425G24Rik MGI:MGI:1923248 +76000 5033430I15Rik MGI:MGI:1923250 +76001 5033426O07Rik MGI:MGI:1923251 +76002 Ms4a18 MGI:MGI:1923252|Ensembl:ENSMUSG00000094584|Vega:OTTMUSG00000046929 +76003 Tmem150cos MGI:MGI:1923253|Ensembl:ENSMUSG00000086259 +76004 5033430J17Rik MGI:MGI:1923254 +76005 5033426E14Rik MGI:MGI:1923255 +76007 Zmym2 MGI:MGI:1923257|Ensembl:ENSMUSG00000021945 +76009 5830415G21Rik MGI:MGI:1923259 +76012 5830415B17Rik MGI:MGI:1923262 +76013 5830407E08Rik MGI:MGI:1923263 +76014 Zc3h18 MGI:MGI:1923264|Ensembl:ENSMUSG00000017478|Vega:OTTMUSG00000042176 +76016 5730406G12Rik MGI:MGI:1923266 +76017 5830411K02Rik MGI:MGI:1923267 +76020 5830409B07Rik MGI:MGI:1923270 +76021 5830418L09Rik MGI:MGI:1923271 +76022 Gon4l MGI:MGI:1917579|Ensembl:ENSMUSG00000054199|Vega:OTTMUSG00000022718 +76024 Gm11346 MGI:MGI:1923274 +76025 Cant1 MGI:MGI:1923275|Ensembl:ENSMUSG00000025575|Vega:OTTMUSG00000003887 +76029 5830432F11Rik MGI:MGI:1923279 +76030 5830433I10Rik MGI:MGI:1923280 +76031 5830448L01Rik MGI:MGI:1923281 +76032 5830438M01Rik MGI:MGI:1923282 +76033 5830435N06Rik MGI:MGI:1923283 +76034 5830434F19Rik MGI:MGI:1923284 +76036 5830431N17Rik MGI:MGI:1923286 +76041 Ccdc125 MGI:MGI:1923291|Ensembl:ENSMUSG00000048924 +76042 5830427D02Rik MGI:MGI:1923292 +76043 5830424K16Rik MGI:MGI:1923293 +76044 Ncapg2 MGI:MGI:1923294|Ensembl:ENSMUSG00000042029 +76045 5830449F15Rik MGI:MGI:1923295 +76047 5830433M15Rik MGI:MGI:1923297 +76048 5830433D23Rik MGI:MGI:1923298 +76050 5830440H09Rik MGI:MGI:1923300 +76051 Ganc MGI:MGI:1923301|Ensembl:ENSMUSG00000062646|Vega:OTTMUSG00000015382 +76052 5830445D09Rik MGI:MGI:1923302 +76053 5830426K05Rik MGI:MGI:1923303 +76055 Mgea5 MGI:MGI:1932139|Ensembl:ENSMUSG00000025220 +76056 5830443J22Rik MGI:MGI:1923306 +76059 5830442K09Rik MGI:MGI:1923309 +76062 5830428M24Rik MGI:MGI:1923312|Ensembl:ENSMUSG00000113035 +76063 5830431M20Rik MGI:MGI:1923313 +76065 5830436C15Rik MGI:MGI:1923315 +76066 5830435N17Rik MGI:MGI:1923316 +76068 5830437K03Rik MGI:MGI:1923318 +76071 Jakmip1 MGI:MGI:1923321|Ensembl:ENSMUSG00000063646|Vega:OTTMUSG00000026769 +76072 Rnf183 MGI:MGI:1923322|Ensembl:ENSMUSG00000063851|Vega:OTTMUSG00000001229 +76073 Pcgf5 MGI:MGI:1923505|Ensembl:ENSMUSG00000024805 +76074 Gbp8 MGI:MGI:1923324|Ensembl:ENSMUSG00000034438|Vega:OTTMUSG00000053799 +76076 5830453K13Rik MGI:MGI:1923326 +76078 5830453J16Rik MGI:MGI:1923328 +76080 Ttpal MGI:MGI:1923330|Ensembl:ENSMUSG00000017679|Vega:OTTMUSG00000001068 +76081 5830458C19Rik MGI:MGI:1923331 +76082 5830468F06Rik MGI:MGI:1923332 +76088 Dock8 MGI:MGI:1921396|Ensembl:ENSMUSG00000052085 +76089 Rapgef2 MGI:MGI:2659071|Ensembl:ENSMUSG00000062232|Vega:OTTMUSG00000031912 +76090 5830454J16Rik MGI:MGI:1923340 +76093 5830469G19Rik MGI:MGI:1923343 +76094 5830474E16Rik MGI:MGI:1923344 +76096 5830468K08Rik MGI:MGI:1923346 +76098 5830462P14Rik MGI:MGI:1923348 +76100 5830454E08Rik MGI:MGI:1923350|Ensembl:ENSMUSG00000052658 +76101 5830461L22Rik MGI:MGI:1923351 +76104 5830472F04Rik MGI:MGI:1923354 +76105 5830456J23Rik MGI:MGI:1923355 +76108 Rap2a MGI:MGI:97855|Ensembl:ENSMUSG00000051615 +76110 5830462O15Rik MGI:MGI:1923360 +76111 5830490A12Rik MGI:MGI:1923361 +76113 Lpo MGI:MGI:1923363|Ensembl:ENSMUSG00000009356|Vega:OTTMUSG00000001439 +76116 5830477G23Rik MGI:MGI:1923366 +76117 Arhgap15 MGI:MGI:1923367|Ensembl:ENSMUSG00000049744|Vega:OTTMUSG00000012329 +76118 5830487J09Rik MGI:MGI:1923368 +76121 5830485P09Rik MGI:MGI:1923371 +76123 Gpsm2 MGI:MGI:1923373|Ensembl:ENSMUSG00000027883|Vega:OTTMUSG00000007258 +76125 5830487K18Rik MGI:MGI:1923375 +76126 5830490A04Rik MGI:MGI:1923376 +76128 5830495A06Rik MGI:MGI:1923378 +76130 Las1l MGI:MGI:1923380|Ensembl:ENSMUSG00000057421|Vega:OTTMUSG00000018162 +76131 Depdc1a MGI:MGI:1923381|Ensembl:ENSMUSG00000028175|Vega:OTTMUSG00000026469 +76132 Faxc MGI:MGI:1923382|Ensembl:ENSMUSG00000028246|Vega:OTTMUSG00000004776 +76133 6230400D17Rik MGI:MGI:1923383 +76137 Mcur1 MGI:MGI:1923387|Ensembl:ENSMUSG00000021371 +76138 Ccdc138 MGI:MGI:1923388|Ensembl:ENSMUSG00000038010 +76141 6230414M07Rik MGI:MGI:1923391 +76142 Ppp1r14c MGI:MGI:1923392|Ensembl:ENSMUSG00000040653|Vega:OTTMUSG00000063466 +76143 6230426I18Rik MGI:MGI:1923393 +76156 Fam131b MGI:MGI:1923406|Ensembl:ENSMUSG00000029861|Vega:OTTMUSG00000033751 +76157 Slc35d3 MGI:MGI:1923407|Ensembl:ENSMUSG00000050473|Vega:OTTMUSG00000063798 +76158 6330510M09Rik MGI:MGI:1923408 +76161 Lamp5 MGI:MGI:1923411|Ensembl:ENSMUSG00000027270|Vega:OTTMUSG00000015982 +76163 6330537M06Rik MGI:MGI:1923413 +76166 Rsg1 MGI:MGI:1923416|Ensembl:ENSMUSG00000073733|Vega:OTTMUSG00000010149 +76167 Snrnp35 MGI:MGI:1923417|Ensembl:ENSMUSG00000029402|Vega:OTTMUSG00000024446 +76169 6330525I24Rik MGI:MGI:1923419 +76173 6330531I01Rik MGI:MGI:1923423 +76174 6330526H18Rik MGI:MGI:1923424 +76177 6330565B04Rik MGI:MGI:1923427 +76178 Coa5 MGI:MGI:1923428|Ensembl:ENSMUSG00000026112|Vega:OTTMUSG00000022117 +76179 Usp31 MGI:MGI:1923429|Ensembl:ENSMUSG00000063317|Vega:OTTMUSG00000058098 +76183 Celf6 MGI:MGI:1923433|Ensembl:ENSMUSG00000032297|Vega:OTTMUSG00000027385 +76184 Abca6 MGI:MGI:1923434|Ensembl:ENSMUSG00000044749|Vega:OTTMUSG00000003327 +76186 6330563C09Rik MGI:MGI:1923436 +76187 Adhfe1 MGI:MGI:1923437|Ensembl:ENSMUSG00000025911|Vega:OTTMUSG00000022305 +76188 6330571C24Rik MGI:MGI:1923438 +76192 Abhd12 MGI:MGI:1923442|Ensembl:ENSMUSG00000032046|Vega:OTTMUSG00000015774 +76193 6330562C20Rik MGI:MGI:1923443 +76195 6330590E21Rik MGI:MGI:1923445 +76196 6330575P09Rik MGI:MGI:1923446 +76198 6330576A10Rik MGI:MGI:1923448 +76199 Med13l MGI:MGI:2670178|Ensembl:ENSMUSG00000018076|Vega:OTTMUSG00000056228 +76203 6430605C03Rik MGI:MGI:1923453 +76205 Stard3nl MGI:MGI:1923455|Ensembl:ENSMUSG00000003062|Vega:OTTMUSG00000054348 +76206 Gpr165 MGI:MGI:1923456|Ensembl:ENSMUSG00000031210|Vega:OTTMUSG00000018039 +76212 6530403M18Rik MGI:MGI:1923462 +76213 6530406A20Rik MGI:MGI:1923463 +76214 6430710M23Rik MGI:MGI:1923464 +76215 6530413G14Rik MGI:MGI:1923465 +76217 Jakmip2 MGI:MGI:1923467|Ensembl:ENSMUSG00000024502 +76218 6430710C18Rik MGI:MGI:1923468|Ensembl:ENSMUSG00000085427 +76219 Arxes1 MGI:MGI:1923469|Ensembl:ENSMUSG00000048355|Vega:OTTMUSG00000018756 +76220 6530402F18Rik MGI:MGI:1923470|Ensembl:ENSMUSG00000079499 +76221 6430598H11Rik MGI:MGI:1923471 +76222 Magef1 MGI:MGI:1923472 +76223 Agbl3 MGI:MGI:1923473|Ensembl:ENSMUSG00000038836|Vega:OTTMUSG00000014803 +76224 6530409C15Rik MGI:MGI:1923474 +76225 6430711C07Rik MGI:MGI:1923475 +76227 6530403G13Rik MGI:MGI:1923477 +76229 Vmn2r29 MGI:MGI:1923479|Ensembl:ENSMUSG00000095730|Ensembl:ENSMUSG00000110105|Vega:OTTMUSG00000037803|Vega:OTTMUSG00000060184 +76233 Dnttip1 MGI:MGI:1923483|Ensembl:ENSMUSG00000017299|Vega:OTTMUSG00000001100 +76237 6430628N08Rik MGI:MGI:1923487|Ensembl:ENSMUSG00000034185|Vega:OTTMUSG00000008712 +76238 Grhpr MGI:MGI:1923488|Ensembl:ENSMUSG00000035637|Vega:OTTMUSG00000007141 +76240 6430709C05Rik MGI:MGI:1923490 +76241 6530401F13Rik MGI:MGI:1923491 +76246 Rtf1 MGI:MGI:1309480|Ensembl:ENSMUSG00000027304|Vega:OTTMUSG00000016508 +76251 Ercc6l2 MGI:MGI:1923501|Ensembl:ENSMUSG00000021470|Vega:OTTMUSG00000026114 +76252 Atp6v0e2 MGI:MGI:1923502|Ensembl:ENSMUSG00000039347|Vega:OTTMUSG00000057232 +76253 0610006L08Rik MGI:MGI:1923503 +76257 Slc38a3 MGI:MGI:1923507|Ensembl:ENSMUSG00000010064|Vega:OTTMUSG00000050784 +76260 Ttc8 MGI:MGI:1923510|Ensembl:ENSMUSG00000021013|Vega:OTTMUSG00000023820 +76261 0610040J01Rik MGI:MGI:1923511|Ensembl:ENSMUSG00000060512|Vega:OTTMUSG00000055109 +76263 Gstk1 MGI:MGI:1923513|Ensembl:ENSMUSG00000029864|Vega:OTTMUSG00000057543 +76265 Tsen54 MGI:MGI:1923515|Ensembl:ENSMUSG00000020781|Vega:OTTMUSG00000003539 +76267 Fads1 MGI:MGI:1923517|Ensembl:ENSMUSG00000010663 +76273 Ndfip2 MGI:MGI:1923523|Ensembl:ENSMUSG00000053253|Vega:OTTMUSG00000032794 +76279 Cyp2d26 MGI:MGI:1923529|Ensembl:ENSMUSG00000022445 +76281 Tax1bp3 MGI:MGI:1923531|Ensembl:ENSMUSG00000040158|Vega:OTTMUSG00000006115 +76282 Gpt MGI:MGI:95802|Ensembl:ENSMUSG00000022546 +76286 1110006E14Rik MGI:MGI:1923536 +76293 Mfap4 MGI:MGI:1342276|Ensembl:ENSMUSG00000042436|Vega:OTTMUSG00000005836 +76294 Asb5 MGI:MGI:1923544|Ensembl:ENSMUSG00000031519|Vega:OTTMUSG00000060620 +76295 Atp11b MGI:MGI:1923545|Ensembl:ENSMUSG00000037400|Vega:OTTMUSG00000022012 +76299 Erp44 MGI:MGI:1923549|Ensembl:ENSMUSG00000028343|Vega:OTTMUSG00000006817 +76302 Pcnp MGI:MGI:1923552|Ensembl:ENSMUSG00000071533|Vega:OTTMUSG00000025837 +76303 Osbp MGI:MGI:97447|Ensembl:ENSMUSG00000024687 +76306 Slc18b1 MGI:MGI:1923556|Ensembl:ENSMUSG00000037455|Vega:OTTMUSG00000030782 +76308 Rab1b MGI:MGI:1923558|Ensembl:ENSMUSG00000024870 +76311 1110019D14Rik MGI:MGI:1923561|Ensembl:ENSMUSG00000097616 +76332 Cog2 MGI:MGI:1923582|Ensembl:ENSMUSG00000031979|Vega:OTTMUSG00000023539 +76338 Rab2b MGI:MGI:1923588|Ensembl:ENSMUSG00000022159|Vega:OTTMUSG00000038080 +76355 Tgds MGI:MGI:1923605|Ensembl:ENSMUSG00000022130 +76357 Trmt5 MGI:MGI:1923607|Ensembl:ENSMUSG00000034442 +76359 2610028D06Rik MGI:MGI:1923609 +76362 2610034O05Rik MGI:MGI:1923612 +76365 Tbx18 MGI:MGI:1923615|Ensembl:ENSMUSG00000032419|Vega:OTTMUSG00000045141 +76366 Mtif3 MGI:MGI:1923616|Ensembl:ENSMUSG00000016510|Vega:OTTMUSG00000024605 +76367 Trp53rkb MGI:MGI:1914050|Ensembl:ENSMUSG00000042854|Vega:OTTMUSG00000016148 +76368 2610028L16Rik MGI:MGI:1923618 +76371 2810408B13Rik MGI:MGI:1923621 +76373 Zfp773 MGI:MGI:1923623|Ensembl:ENSMUSG00000063535|Vega:OTTMUSG00000060213 +76375 Det1 MGI:MGI:1923625|Ensembl:ENSMUSG00000030610|Vega:OTTMUSG00000023009 +76376 Slc24a2 MGI:MGI:1923626|Ensembl:ENSMUSG00000037996|Vega:OTTMUSG00000007637 +76377 Gm9734 MGI:MGI:3804254 +76378 Ropn1 MGI:MGI:1923628|Ensembl:ENSMUSG00000022832|Vega:OTTMUSG00000026547 +76379 1700001N15Rik MGI:MGI:1923629 +76380 Cep112 MGI:MGI:1923673|Ensembl:ENSMUSG00000020728|Vega:OTTMUSG00000003155 +76382 1700012A03Rik MGI:MGI:1923632|Ensembl:ENSMUSG00000029766 +76383 H2al1m MGI:MGI:1923633|Ensembl:ENSMUSG00000100200|Vega:OTTMUSG00000016891 +76385 1700012C08Rik MGI:MGI:1923635 +76386 1700010D01Rik MGI:MGI:1923636 +76389 Ankrd36 MGI:MGI:1923639|Ensembl:ENSMUSG00000020481|Vega:OTTMUSG00000005087 +76390 Zfp735 MGI:MGI:1923640|Ensembl:ENSMUSG00000060630|Vega:OTTMUSG00000006145 +76392 Slfn5os MGI:MGI:1923642|Ensembl:ENSMUSG00000086327 +76393 1700012H19Rik MGI:MGI:1923643 +76394 1700012M20Rik MGI:MGI:1923644 +76397 4930455F16Rik MGI:MGI:1922126 +76398 1700017M07Rik MGI:MGI:1923648|Ensembl:ENSMUSG00000105651 +76399 Il31 MGI:MGI:1923649|Ensembl:ENSMUSG00000029437|Vega:OTTMUSG00000054631 +76400 Pbp2 MGI:MGI:1923650|Ensembl:ENSMUSG00000047104|Vega:OTTMUSG00000057201 +76402 1700020M21Rik MGI:MGI:1923652|Ensembl:ENSMUSG00000100146 +76405 1700018B08Rik MGI:MGI:1923655|Ensembl:ENSMUSG00000031809|Vega:OTTMUSG00000043050 +76406 Tex45 MGI:MGI:1923656|Ensembl:ENSMUSG00000040340|Vega:OTTMUSG00000033175 +76407 Sun5 MGI:MGI:1923657|Ensembl:ENSMUSG00000027480|Vega:OTTMUSG00000016828 +76408 Abcc3 MGI:MGI:1923658|Ensembl:ENSMUSG00000020865|Vega:OTTMUSG00000001891 +76409 1700025B11Rik MGI:MGI:1923659|Ensembl:ENSMUSG00000101113|Vega:OTTMUSG00000045152 +76410 1700021L23Rik MGI:MGI:1923660 +76411 Ift43 MGI:MGI:1923661|Ensembl:ENSMUSG00000007867 +76412 1700019J19Rik MGI:MGI:1923662 +76413 1700016D06Rik MGI:MGI:1923663|Ensembl:ENSMUSG00000031509|Vega:OTTMUSG00000045114 +76415 Fam187b MGI:MGI:1923665|Ensembl:ENSMUSG00000046826|Vega:OTTMUSG00000030140 +76416 Znrd1as MGI:MGI:1923666|Ensembl:ENSMUSG00000036214|Vega:OTTMUSG00000037386 +76418 Gm16530 MGI:MGI:4361947 +76419 Smkr-ps MGI:MGI:1923669|Ensembl:ENSMUSG00000045709 +76421 1700028K03Rik MGI:MGI:1923671|Ensembl:ENSMUSG00000089798|Vega:OTTMUSG00000023575 +76422 Mroh3 MGI:MGI:1923672 +76425 Gid8 MGI:MGI:1923675|Ensembl:ENSMUSG00000027573|Vega:OTTMUSG00000016366 +76426 Fam209 MGI:MGI:1923676|Ensembl:ENSMUSG00000027505|Vega:OTTMUSG00000016247 +76429 Lhpp MGI:MGI:1923679|Ensembl:ENSMUSG00000030946|Vega:OTTMUSG00000024032 +76432 2310001H17Rik MGI:MGI:1923682|Ensembl:ENSMUSG00000097354 +76438 Rftn1 MGI:MGI:1923688|Ensembl:ENSMUSG00000039316|Vega:OTTMUSG00000023326 +76441 Daam2 MGI:MGI:1923691|Ensembl:ENSMUSG00000040260 +76443 2310016D23Rik MGI:MGI:1923693 +76444 Krtap4-7 MGI:MGI:1923694|Ensembl:ENSMUSG00000045109|Vega:OTTMUSG00000002202 +76448 Ppp1r18 MGI:MGI:1923698|Ensembl:ENSMUSG00000034595|Vega:OTTMUSG00000032936 +76453 Prss23 MGI:MGI:1923703|Ensembl:ENSMUSG00000039405|Vega:OTTMUSG00000059648 +76454 Fbxo31 MGI:MGI:1354708|Ensembl:ENSMUSG00000052934|Vega:OTTMUSG00000043031 +76455 2310067E19Rik MGI:MGI:1923705 +76457 Ccdc134 MGI:MGI:1923707|Ensembl:ENSMUSG00000068114 +76459 Car12 MGI:MGI:1923709|Ensembl:ENSMUSG00000032373|Vega:OTTMUSG00000025353 +76464 Knl1 MGI:MGI:1923714|Ensembl:ENSMUSG00000027326|Vega:OTTMUSG00000015766 +76467 Msrb2 MGI:MGI:1923717|Ensembl:ENSMUSG00000023094|Vega:OTTMUSG00000011492 +76469 Cmya5 MGI:MGI:1923719|Ensembl:ENSMUSG00000047419 +76477 Pcolce2 MGI:MGI:1923727|Ensembl:ENSMUSG00000015354|Vega:OTTMUSG00000030790 +76478 Haus8 MGI:MGI:1923728|Ensembl:ENSMUSG00000035439|Vega:OTTMUSG00000031956 +76479 Smndc1 MGI:MGI:1923729|Ensembl:ENSMUSG00000025024 +76482 3110002H16Rik MGI:MGI:1916528|Ensembl:ENSMUSG00000024410|Vega:OTTMUSG00000028184 +76483 Lmf1 MGI:MGI:1923733|Ensembl:ENSMUSG00000002279|Vega:OTTMUSG00000031244 +76484 Kndc1 MGI:MGI:1923734|Ensembl:ENSMUSG00000066129 +76485 Glt8d1 MGI:MGI:1923735|Ensembl:ENSMUSG00000021916 +76486 Ly6k MGI:MGI:1923736|Ensembl:ENSMUSG00000044678|Vega:OTTMUSG00000035280 +76487 Ppp1r3g MGI:MGI:1923737|Ensembl:ENSMUSG00000050423|Vega:OTTMUSG00000033597 +76491 Abhd14b MGI:MGI:1923741|Ensembl:ENSMUSG00000042073|Vega:OTTMUSG00000049534 +76497 Ppp1r11 MGI:MGI:1923747|Ensembl:ENSMUSG00000036398|Vega:OTTMUSG00000037384 +76498 Paqr4 MGI:MGI:1923748|Ensembl:ENSMUSG00000023909 +76499 Clasp2 MGI:MGI:1923749|Ensembl:ENSMUSG00000033392|Vega:OTTMUSG00000062438 +76500 Ip6k2 MGI:MGI:1923750|Ensembl:ENSMUSG00000032599|Vega:OTTMUSG00000050674 +76501 Commd9 MGI:MGI:1923751|Ensembl:ENSMUSG00000027163|Vega:OTTMUSG00000015046 +76505 1500009C09Rik MGI:MGI:1923755|Ensembl:ENSMUSG00000068099|Vega:OTTMUSG00000033544 +76507 Aoc1 MGI:MGI:1923757|Ensembl:ENSMUSG00000029811|Vega:OTTMUSG00000034260 +76508 Ube2d-ps MGI:MGI:1913774|Ensembl:ENSMUSG00000083844 +76509 Plet1 MGI:MGI:1923759|Ensembl:ENSMUSG00000032068|Vega:OTTMUSG00000048527 +76510 Trappc9 MGI:MGI:1923760|Ensembl:ENSMUSG00000047921 +76511 2010004M13Rik MGI:MGI:1923761 +76513 1810058N15Rik MGI:MGI:1923763 +76516 2010001A14Rik MGI:MGI:1923766|Ensembl:ENSMUSG00000087165 +76522 Lsm8 MGI:MGI:1923772|Ensembl:ENSMUSG00000044155|Vega:OTTMUSG00000024331 +76524 Cln6 MGI:MGI:2159324|Ensembl:ENSMUSG00000032245|Vega:OTTMUSG00000033326 +76527 Il34 MGI:MGI:1923777|Ensembl:ENSMUSG00000031750|Vega:OTTMUSG00000027476 +76531 2600001M11Rik MGI:MGI:1923781 +76533 2010106G04Rik MGI:MGI:1923783 +76539 Fam204a MGI:MGI:1289174|Ensembl:ENSMUSG00000057858 +76547 Tmem101 MGI:MGI:1923797|Ensembl:ENSMUSG00000020921|Vega:OTTMUSG00000002493 +76551 Ccdc6 MGI:MGI:1923801|Ensembl:ENSMUSG00000048701|Vega:OTTMUSG00000032767 +76559 Atg2b MGI:MGI:1923809|Ensembl:ENSMUSG00000041341 +76560 Prss8 MGI:MGI:1923810|Ensembl:ENSMUSG00000030800|Vega:OTTMUSG00000058635 +76561 Snx7 MGI:MGI:1923811|Ensembl:ENSMUSG00000028007|Vega:OTTMUSG00000035935 +76563 Qrsl1 MGI:MGI:1923813|Ensembl:ENSMUSG00000019863|Vega:OTTMUSG00000023049 +76566 Rflnb MGI:MGI:1923816|Ensembl:ENSMUSG00000020846|Vega:OTTMUSG00000006222 +76567 1700012E03Rik MGI:MGI:1923817 +76568 Ift46 MGI:MGI:1923818|Ensembl:ENSMUSG00000002031|Vega:OTTMUSG00000026615 +76571 Styxl1 MGI:MGI:1923821|Ensembl:ENSMUSG00000019178|Vega:OTTMUSG00000022780 +76572 Rbmxl2 MGI:MGI:1923822|Ensembl:ENSMUSG00000073894|Vega:OTTMUSG00000022833 +76573 Spatc1l MGI:MGI:1923823|Ensembl:ENSMUSG00000009115|Vega:OTTMUSG00000020434 +76574 Mfsd2a MGI:MGI:1923824|Ensembl:ENSMUSG00000028655|Vega:OTTMUSG00000008939 +76577 Faf2 MGI:MGI:1923827|Ensembl:ENSMUSG00000025873|Vega:OTTMUSG00000032681 +76580 Mib2 MGI:MGI:2679684|Ensembl:ENSMUSG00000029060|Vega:OTTMUSG00000010733 +76582 Ipo11 MGI:MGI:2442377|Ensembl:ENSMUSG00000042590|Vega:OTTMUSG00000045106 +76585 Lce1i MGI:MGI:1923835|Ensembl:ENSMUSG00000068888|Vega:OTTMUSG00000051857 +76589 Unc5cl MGI:MGI:1923839|Ensembl:ENSMUSG00000043592|Vega:OTTMUSG00000028421 +76590 2510010E17Rik MGI:MGI:1923840 +76594 Dnajc18 MGI:MGI:1923844|Ensembl:ENSMUSG00000024350 +76601 1700041M19Rik MGI:MGI:1923851|Ensembl:ENSMUSG00000100857 +76602 1700040D17Rik MGI:MGI:1923852|Ensembl:ENSMUSG00000097515 +76603 1700047N06Rik MGI:MGI:1923853 +76604 1700047A11Rik MGI:MGI:1923854|Ensembl:ENSMUSG00000085437 +76605 1700042O13Rik MGI:MGI:1923855 +76606 1700034O15Rik MGI:MGI:1923856|Ensembl:ENSMUSG00000029867|Vega:OTTMUSG00000051431 +76607 1700058J15Rik MGI:MGI:1923857 +76608 Hectd3 MGI:MGI:1923858|Ensembl:ENSMUSG00000046861|Vega:OTTMUSG00000009776 +76609 1700065O20Rik MGI:MGI:1923859|Ensembl:ENSMUSG00000100134 +76610 1700063K16Rik MGI:MGI:1923860 +76611 1700071A11Rik MGI:MGI:1923861 +76612 Lrrc27 MGI:MGI:1923862|Ensembl:ENSMUSG00000015980|Vega:OTTMUSG00000024425 +76613 1700069B07Rik MGI:MGI:1923863 +76614 Immt MGI:MGI:1923864|Ensembl:ENSMUSG00000052337|Vega:OTTMUSG00000035844 +76615 Got1l1 MGI:MGI:1923865|Ensembl:ENSMUSG00000039720|Vega:OTTMUSG00000061026 +76618 1700084C06Rik MGI:MGI:1923868 +76619 1700087I21Rik MGI:MGI:1923869 +76621 1700106J12Rik MGI:MGI:1923871 +76623 1700093C20Rik MGI:MGI:1923873 +76624 1700099I09Rik MGI:MGI:1923874|Ensembl:ENSMUSG00000091906 +76626 Msi2 MGI:MGI:1923876|Ensembl:ENSMUSG00000069769|Vega:OTTMUSG00000008130 +76627 Prr30 MGI:MGI:1923877|Ensembl:ENSMUSG00000042888|Vega:OTTMUSG00000045421 +76628 1700112J16Rik MGI:MGI:1923878|Ensembl:ENSMUSG00000097527 +76629 Wbscr28 MGI:MGI:1923879|Ensembl:ENSMUSG00000040576|Vega:OTTMUSG00000055809 +76630 Stambpl1 MGI:MGI:1923880|Ensembl:ENSMUSG00000024776|Vega:OTTMUSG00000028400 +76632 1700093P08Rik MGI:MGI:1923882 +76633 Lrmda MGI:MGI:1923883|Ensembl:ENSMUSG00000063458|Vega:OTTMUSG00000034628 +76634 1700110C19Rik MGI:MGI:1923884|Ensembl:ENSMUSG00000099384 +76635 1700110C23Rik MGI:MGI:1923885 +76637 Zim2 MGI:MGI:1923887|Ensembl:ENSMUSG00000108113 +76639 1700121N20Rik MGI:MGI:1923889|Ensembl:ENSMUSG00000092066 +76640 1700113H08Rik MGI:MGI:1923890|Ensembl:ENSMUSG00000047129|Vega:OTTMUSG00000045441 +76641 1700123N01Rik MGI:MGI:1923891 +76642 1700113A16Rik MGI:MGI:1923892|Ensembl:ENSMUSG00000096935 +76643 1700121L16Rik MGI:MGI:1923893|Ensembl:ENSMUSG00000100364 +76645 Pkd1l2 MGI:MGI:2664668|Ensembl:ENSMUSG00000034416|Vega:OTTMUSG00000021101 +76646 Wdr38 MGI:MGI:1923896|Ensembl:ENSMUSG00000035295|Vega:OTTMUSG00000012349 +76648 1700126G02Rik MGI:MGI:1923898 +76649 1700119H24Rik MGI:MGI:1923899|Ensembl:ENSMUSG00000100593 +76650 Srxn1 MGI:MGI:104971|Ensembl:ENSMUSG00000032802|Vega:OTTMUSG00000015842 +76651 1700122O11Rik MGI:MGI:1923901|Ensembl:ENSMUSG00000094928|Vega:OTTMUSG00000045505 +76652 Actrt3 MGI:MGI:1923902|Ensembl:ENSMUSG00000037737|Vega:OTTMUSG00000029284 +76653 Cby3 MGI:MGI:1923903 +76654 Upp2 MGI:MGI:1923904|Ensembl:ENSMUSG00000026839|Vega:OTTMUSG00000012752 +76656 1700120O09Rik MGI:MGI:1923906 +76657 1700125G22Rik MGI:MGI:1923907|Ensembl:ENSMUSG00000097584 +76658 1700123K08Rik MGI:MGI:1923908|Ensembl:ENSMUSG00000029526|Vega:OTTMUSG00000054714 +76660 1700121L03Rik MGI:MGI:1923910 +76661 1700122D07Rik MGI:MGI:1923911 +76662 1700120C18Rik MGI:MGI:1923912 +76666 1700120E02Rik MGI:MGI:1923916 +76668 Mdh1b MGI:MGI:1923918|Ensembl:ENSMUSG00000025963|Vega:OTTMUSG00000008270 +76669 1700128F08Rik MGI:MGI:1923919|Ensembl:ENSMUSG00000031998 +76670 Cfap70 MGI:MGI:1923920|Ensembl:ENSMUSG00000039543|Vega:OTTMUSG00000032888 +76671 5330406M23Rik MGI:MGI:1923921 +76673 5330411O13Rik MGI:MGI:1923923 +76675 5330403D14Rik MGI:MGI:1923925 +76676 5330411J11Rik MGI:MGI:1923926|Ensembl:ENSMUSG00000087455 +76679 5330417H12Rik MGI:MGI:1923929 +76681 Trim12a MGI:MGI:1923931|Ensembl:ENSMUSG00000066258|Vega:OTTMUSG00000019179 +76682 1500002K03Rik MGI:MGI:1923932 +76683 1500002F19Rik MGI:MGI:1923933 +76684 Pla2g10os MGI:MGI:1923934 +76686 Clip3 MGI:MGI:1923936|Ensembl:ENSMUSG00000013921|Vega:OTTMUSG00000024314 +76687 Spcs3 MGI:MGI:1923937|Ensembl:ENSMUSG00000054408|Vega:OTTMUSG00000034015 +76688 Arfrp1 MGI:MGI:1923938|Ensembl:ENSMUSG00000038671|Vega:OTTMUSG00000016653 +76690 1500037F05Rik MGI:MGI:1923940 +76691 2010110E17Rik MGI:MGI:1923941 +76694 1810029E06Rik MGI:MGI:1923944 +76699 1700003I16Rik MGI:MGI:1923949 +76701 Ctrc MGI:MGI:1923951|Ensembl:ENSMUSG00000062478|Vega:OTTMUSG00000010017 +76703 Cpb1 MGI:MGI:1923953|Ensembl:ENSMUSG00000011463|Vega:OTTMUSG00000024346 +76705 Ppp1r2-ps7 MGI:MGI:1923955 +76707 Clasp1 MGI:MGI:1923957|Ensembl:ENSMUSG00000064302|Vega:OTTMUSG00000048576 +76709 Arpc2 MGI:MGI:1923959|Ensembl:ENSMUSG00000006304|Vega:OTTMUSG00000016449 +76710 2210406O10Rik MGI:MGI:1923960|Ensembl:ENSMUSG00000039563 +76713 Slc6a21 MGI:MGI:1923963|Ensembl:ENSMUSG00000070568|Vega:OTTMUSG00000039915 +76714 1700040G22Rik MGI:MGI:1923964 +76718 Catsperg2 MGI:MGI:1923968|Ensembl:ENSMUSG00000049123|Vega:OTTMUSG00000059220 +76719 Kansl1 MGI:MGI:1923969|Ensembl:ENSMUSG00000018412|Vega:OTTMUSG00000003147 +76720 1700084D21Rik MGI:MGI:1923970 +76721 1700085B13Rik MGI:MGI:1923971 +76722 Ckmt2 MGI:MGI:1923972|Ensembl:ENSMUSG00000021622|Vega:OTTMUSG00000029571 +76725 2010003D24Rik MGI:MGI:1923975 +76726 1700121F22Rik MGI:MGI:1923976 +76728 1700123J17Rik MGI:MGI:1923978|Ensembl:ENSMUSG00000108676 +76729 2310001K20Rik MGI:MGI:1923979 +76733 6330436F06Rik MGI:MGI:1923983 +76734 6330437I11Rik MGI:MGI:1923984 +76737 Creld2 MGI:MGI:1923987|Ensembl:ENSMUSG00000023272 +76740 Efr3a MGI:MGI:1923990|Ensembl:ENSMUSG00000015002|Vega:OTTMUSG00000036980 +76742 Snx27 MGI:MGI:1923992|Ensembl:ENSMUSG00000028136|Vega:OTTMUSG00000019563 +76743 Gje1 MGI:MGI:1923993|Ensembl:ENSMUSG00000019867|Vega:OTTMUSG00000020913 +76747 Dapl1 MGI:MGI:1923997|Ensembl:ENSMUSG00000026989|Vega:OTTMUSG00000012705 +76754 2310039F13Rik MGI:MGI:1924004 +76755 2310045N14Rik MGI:MGI:1924005 +76757 Trdn MGI:MGI:1924007|Ensembl:ENSMUSG00000019787 +76758 Gsdma2 MGI:MGI:1921490|Ensembl:ENSMUSG00000017211|Vega:OTTMUSG00000006395 +76760 1810044K17Rik MGI:MGI:1924010 +76763 Mospd2 MGI:MGI:1924013|Ensembl:ENSMUSG00000061778|Vega:OTTMUSG00000019521 +76768 Alpi MGI:MGI:1924018|Ensembl:ENSMUSG00000079440|Vega:OTTMUSG00000048153 +76769 2010003K10Rik MGI:MGI:1924019 +76770 2010005H15Rik MGI:MGI:1924020|Ensembl:ENSMUSG00000095620|Vega:OTTMUSG00000045936 +76772 2410049M19Rik MGI:MGI:1924022 +76773 Wdyhv1 MGI:MGI:1924023|Ensembl:ENSMUSG00000022359 +76775 Slc10a7 MGI:MGI:1924025|Ensembl:ENSMUSG00000031684|Vega:OTTMUSG00000061289 +76776 2410084L01Rik MGI:MGI:1924026 +76779 Cluap1 MGI:MGI:1924029|Ensembl:ENSMUSG00000014232|Vega:OTTMUSG00000042236 +76781 Mettl4 MGI:MGI:1924031|Ensembl:ENSMUSG00000055660 +76782 2410198J08Rik MGI:MGI:1924032 +76784 Mtif2 MGI:MGI:1924034|Ensembl:ENSMUSG00000020459|Vega:OTTMUSG00000005326 +76785 2410124H12Rik MGI:MGI:1924035 +76786 2510003B16Rik MGI:MGI:1924036|Ensembl:ENSMUSG00000028700 +76787 Ppfia3 MGI:MGI:1924037|Ensembl:ENSMUSG00000003863|Vega:OTTMUSG00000023803 +76788 Klhdc10 MGI:MGI:1924038|Ensembl:ENSMUSG00000029775|Vega:OTTMUSG00000014355 +76789 Mzt1 MGI:MGI:1924039|Ensembl:ENSMUSG00000033186 +76792 2410131K14Rik MGI:MGI:1924042|Ensembl:ENSMUSG00000032840|Vega:OTTMUSG00000028968 +76793 Snip1 MGI:MGI:2156003|Ensembl:ENSMUSG00000050213|Vega:OTTMUSG00000009251 +76794 Man2c1os MGI:MGI:1924044|Ensembl:ENSMUSG00000086728 +76795 Tbc1d9b MGI:MGI:1924045|Ensembl:ENSMUSG00000036644|Vega:OTTMUSG00000005576 +76797 2410137M14Rik MGI:MGI:1924047|Ensembl:ENSMUSG00000064308|Vega:OTTMUSG00000014935 +76798 Srrm4os MGI:MGI:1924048|Ensembl:ENSMUSG00000086219 +76799 Tmem234 MGI:MGI:1924049|Ensembl:ENSMUSG00000028797|Vega:OTTMUSG00000009510 +76800 Usp42 MGI:MGI:1924050|Ensembl:ENSMUSG00000051306|Vega:OTTMUSG00000025563 +76803 2410141K09Rik MGI:MGI:1924053|Ensembl:ENSMUSG00000074832|Vega:OTTMUSG00000037185 +76804 Kdm4c MGI:MGI:1924054|Ensembl:ENSMUSG00000028397|Vega:OTTMUSG00000000345 +76806 2700029L08Rik MGI:MGI:1924056 +76808 Rpl18a MGI:MGI:1924058|Ensembl:ENSMUSG00000045128|Vega:OTTMUSG00000061602 +76809 Bri3bp MGI:MGI:1924059|Ensembl:ENSMUSG00000037905|Vega:OTTMUSG00000055093 +76811 2410152P15Rik MGI:MGI:1924061 +76813 Armc6 MGI:MGI:1924063|Ensembl:ENSMUSG00000002343|Vega:OTTMUSG00000022201 +76814 Scarletltr MGI:MGI:1924064 +76815 Calcoco2 MGI:MGI:1343177|Ensembl:ENSMUSG00000006056|Vega:OTTMUSG00000001956 +76816 Sdccag8 MGI:MGI:1924066|Ensembl:ENSMUSG00000026504|Vega:OTTMUSG00000021519 +76817 2700052C19Rik MGI:MGI:1924067 +76820 Fam49a MGI:MGI:1261783|Ensembl:ENSMUSG00000020589 +76821 2600017C09Rik MGI:MGI:1924071 +76823 2410164B09Rik MGI:MGI:1924073 +76824 Mtfr1l MGI:MGI:1924074|Ensembl:ENSMUSG00000046671|Vega:OTTMUSG00000011172 +76826 Nubpl MGI:MGI:1924076|Ensembl:ENSMUSG00000035142|Vega:OTTMUSG00000032938 +76829 Dok5 MGI:MGI:1924079|Ensembl:ENSMUSG00000027560|Vega:OTTMUSG00000016127 +76830 2900022B07Rik MGI:MGI:1924080 +76832 Hyls1 MGI:MGI:1924082|Ensembl:ENSMUSG00000050555|Vega:OTTMUSG00000030728 +76835 2900052L18Rik MGI:MGI:1924085 +76843 Dtl MGI:MGI:1924093|Ensembl:ENSMUSG00000037474|Vega:OTTMUSG00000051673 +76846 Rps9 MGI:MGI:1924096|Ensembl:ENSMUSG00000006333|Vega:OTTMUSG00000022990 +76850 Ago4 MGI:MGI:1924100|Ensembl:ENSMUSG00000042500|Vega:OTTMUSG00000009232 +76851 5730575G16Rik MGI:MGI:1924101 +76852 3830403N01Rik MGI:MGI:1924102 +76854 Gper1 MGI:MGI:1924104|Ensembl:ENSMUSG00000053647|Vega:OTTMUSG00000021296 +76856 Catsper3 MGI:MGI:1924106|Ensembl:ENSMUSG00000021499|Vega:OTTMUSG00000027746 +76857 Spopl MGI:MGI:1924107|Ensembl:ENSMUSG00000026771|Vega:OTTMUSG00000011465 +76858 Nlrp14 MGI:MGI:1924108|Ensembl:ENSMUSG00000016626|Vega:OTTMUSG00000028908 +76859 4921518B13Rik MGI:MGI:1924109 +76861 4832441B07Rik MGI:MGI:1924111 +76862 4833405L11Rik MGI:MGI:1924112 +76863 Dcun1d5 MGI:MGI:1924113|Ensembl:ENSMUSG00000032002|Vega:OTTMUSG00000062267 +76865 4930408K08Rik MGI:MGI:1924115 +76866 Morn1 MGI:MGI:1924116|Ensembl:ENSMUSG00000029049|Vega:OTTMUSG00000010600 +76867 Rhbdd1 MGI:MGI:1924117|Ensembl:ENSMUSG00000026142|Vega:OTTMUSG00000021465 +76871 4930422N03Rik MGI:MGI:1924121 +76872 Ccdc116 MGI:MGI:1924122|Ensembl:ENSMUSG00000022768|Vega:OTTMUSG00000026952 +76873 4930447F24Rik MGI:MGI:1924123|Ensembl:ENSMUSG00000102224 +76874 4930469K13Rik MGI:MGI:1924124 +76875 4930516K23Rik MGI:MGI:1924125 +76877 Rab36 MGI:MGI:1924127|Ensembl:ENSMUSG00000020175|Vega:OTTMUSG00000027940 +76878 6330582A15Rik MGI:MGI:1924128 +76880 6430411K18Rik MGI:MGI:1924130 +76882 6430500D05Rik MGI:MGI:1924132 +76883 6430500C12Rik MGI:MGI:1924133 +76884 Cyfip2 MGI:MGI:1924134|Ensembl:ENSMUSG00000020340|Vega:OTTMUSG00000005492 +76885 6430514K02Rik MGI:MGI:1924135 +76886 Fam81a MGI:MGI:1924136|Ensembl:ENSMUSG00000032224|Vega:OTTMUSG00000030841 +76889 Coq8b MGI:MGI:1924139|Ensembl:ENSMUSG00000003762|Vega:OTTMUSG00000023773 +76890 Memo1 MGI:MGI:1924140|Ensembl:ENSMUSG00000058704 +76892 Rnft1 MGI:MGI:1924142|Ensembl:ENSMUSG00000020521|Vega:OTTMUSG00000001201 +76893 Cers2 MGI:MGI:1924143|Ensembl:ENSMUSG00000015714|Vega:OTTMUSG00000027417 +76894 Mettl15 MGI:MGI:1924144|Ensembl:ENSMUSG00000057234|Vega:OTTMUSG00000015096 +76895 Bicd2 MGI:MGI:1924145|Ensembl:ENSMUSG00000037933 +76897 Ralyl MGI:MGI:1924147|Ensembl:ENSMUSG00000039717|Vega:OTTMUSG00000051072 +76898 B3gat1 MGI:MGI:1924148|Ensembl:ENSMUSG00000045994|Vega:OTTMUSG00000028627 +76899 Golga1 MGI:MGI:1924149|Ensembl:ENSMUSG00000026754|Vega:OTTMUSG00000012417 +76900 Ssbp4 MGI:MGI:1924150|Ensembl:ENSMUSG00000070003|Vega:OTTMUSG00000061447 +76901 Jade2 MGI:MGI:1924151|Ensembl:ENSMUSG00000020387|Vega:OTTMUSG00000005611 +76905 Lrg1 MGI:MGI:1924155|Ensembl:ENSMUSG00000037095 +76915 Mnd1 MGI:MGI:1924165|Ensembl:ENSMUSG00000033752|Vega:OTTMUSG00000030256 +76916 Timmdc1 MGI:MGI:1922139|Ensembl:ENSMUSG00000002846|Vega:OTTMUSG00000028158 +76917 Flywch2 MGI:MGI:1924167|Ensembl:ENSMUSG00000023911|Vega:OTTMUSG00000033040 +76918 3110001N23Rik MGI:MGI:1924168 +76920 Arrdc5 MGI:MGI:1924170|Ensembl:ENSMUSG00000073380 +76921 1700013D24Rik MGI:MGI:1924171|Ensembl:ENSMUSG00000079346 +76922 1700014F14Rik MGI:MGI:1924172 +76923 1700014L14Rik MGI:MGI:1924173 +76924 1700021A07Rik MGI:MGI:1924174 +76925 Spata46 MGI:MGI:1924175|Ensembl:ENSMUSG00000042800|Vega:OTTMUSG00000039913 +76926 1700021F13Rik MGI:MGI:1924176 +76927 Tsacc MGI:MGI:1924177|Ensembl:ENSMUSG00000010538|Vega:OTTMUSG00000022019 +76928 1700015C17Rik MGI:MGI:1924178 +76929 1700021N20Rik MGI:MGI:1924179 +76930 1700016P22Rik MGI:MGI:1924180 +76931 1700016C23Rik MGI:MGI:1924181 +76932 Arfip2 MGI:MGI:1924182|Ensembl:ENSMUSG00000030881|Vega:OTTMUSG00000025509 +76933 Ifi27l2a MGI:MGI:1924183|Ensembl:ENSMUSG00000079017|Vega:OTTMUSG00000021961 +76935 1810065K23Rik MGI:MGI:1924185 +76936 Hnrnpm MGI:MGI:1926465|Ensembl:ENSMUSG00000059208|Vega:OTTMUSG00000033297 +76937 2810429I04Rik MGI:MGI:1924187|Ensembl:ENSMUSG00000097709 +76938 Rbm17 MGI:MGI:1924188|Ensembl:ENSMUSG00000037197|Vega:OTTMUSG00000011011 +76939 2510042H12Rik MGI:MGI:1924189 +76941 1700014D06Rik MGI:MGI:1924191 +76942 Lypd5 MGI:MGI:1924192|Ensembl:ENSMUSG00000030484|Vega:OTTMUSG00000058075 +76943 Psapl1 MGI:MGI:1924193|Ensembl:ENSMUSG00000043430|Vega:OTTMUSG00000028038 +76946 2310029O18Rik MGI:MGI:1924196 +76947 Ndufaf6 MGI:MGI:1924197|Ensembl:ENSMUSG00000050323|Vega:OTTMUSG00000004510 +76949 2810404I24Rik MGI:MGI:1924199 +76950 2900001G08Rik MGI:MGI:1924200 +76952 Nt5c2 MGI:MGI:2178563|Ensembl:ENSMUSG00000025041|Vega:OTTMUSG00000037178 +76954 St5 MGI:MGI:108517|Ensembl:ENSMUSG00000031024|Vega:OTTMUSG00000060125 +76956 2900001A22Rik MGI:MGI:1924206 +76957 2210019G11Rik MGI:MGI:1924207 +76959 Chmp5 MGI:MGI:1924209|Ensembl:ENSMUSG00000028419|Vega:OTTMUSG00000006611 +76960 Bcas1 MGI:MGI:1924210|Ensembl:ENSMUSG00000013523|Vega:OTTMUSG00000016099 +76961 2210420H20Rik MGI:MGI:1924211|Ensembl:ENSMUSG00000101773 +76963 2310076G05Rik MGI:MGI:1924213 +76964 2610028H24Rik MGI:MGI:1924214|Ensembl:ENSMUSG00000009114|Vega:OTTMUSG00000020349 +76965 Slitrk1 MGI:MGI:2679446|Ensembl:ENSMUSG00000075478 +76967 2700049A03Rik MGI:MGI:1924217|Ensembl:ENSMUSG00000034601|Vega:OTTMUSG00000033139 +76968 2310046K23Rik MGI:MGI:1924218 +76969 Chst1 MGI:MGI:1924219|Ensembl:ENSMUSG00000027221|Vega:OTTMUSG00000014572 +76971 Sult2a8 MGI:MGI:1924221|Ensembl:ENSMUSG00000030378|Vega:OTTMUSG00000021849 +76972 Snhg20 MGI:MGI:1924222|Ensembl:ENSMUSG00000086859 +76974 Urah MGI:MGI:1916142|Ensembl:ENSMUSG00000025481|Vega:OTTMUSG00000024526 +76975 2900057H02Rik MGI:MGI:1924225 +76976 Arxes2 MGI:MGI:1924226|Ensembl:ENSMUSG00000048040|Vega:OTTMUSG00000018764 +76980 Ube2ql1 MGI:MGI:1924230|Ensembl:ENSMUSG00000052981 +76982 3110035E14Rik MGI:MGI:1924232|Ensembl:ENSMUSG00000067879|Vega:OTTMUSG00000022603 +76983 Scfd1 MGI:MGI:1924233|Ensembl:ENSMUSG00000020952 +76987 Hdhd2 MGI:MGI:1924237|Ensembl:ENSMUSG00000025421|Vega:OTTMUSG00000033486 +76990 1700040E09Rik MGI:MGI:1924240 +76991 1700061E18Rik MGI:MGI:1924241 +76992 Fam219aos MGI:MGI:1924242|Ensembl:ENSMUSG00000036162 +76993 1700061J23Rik MGI:MGI:1924243|Ensembl:ENSMUSG00000086366 +76995 1700095A13Rik MGI:MGI:1924245 +76997 1700123C12Rik MGI:MGI:1924247 +76998 Fbxw27 MGI:MGI:1924248|Ensembl:ENSMUSG00000104614|Vega:OTTMUSG00000051576 +77001 1700110I07Rik MGI:MGI:1924251|Ensembl:ENSMUSG00000108490 +77002 2200002A13Rik MGI:MGI:1924252 +77006 Ddrgk1 MGI:MGI:1924256|Ensembl:ENSMUSG00000068290|Vega:OTTMUSG00000015512 +77011 Ticrr MGI:MGI:1924261|Ensembl:ENSMUSG00000046591|Vega:OTTMUSG00000058577 +77012 5730596P11Rik MGI:MGI:1924262 +77014 2700079J08Rik MGI:MGI:1924264 +77015 Mpped2 MGI:MGI:1924265|Ensembl:ENSMUSG00000016386|Vega:OTTMUSG00000015042 +77017 E130018N17Rik MGI:MGI:1924267|Ensembl:ENSMUSG00000087648 +77018 Col25a1 MGI:MGI:1924268|Ensembl:ENSMUSG00000058897|Vega:OTTMUSG00000022680 +77022 2700099C18Rik MGI:MGI:1924272|Ensembl:ENSMUSG00000098090 +77024 2700057C20Rik MGI:MGI:1924274 +77027 4432414F05Rik MGI:MGI:1924277 +77028 4921520E09Rik MGI:MGI:1924278 +77030 4833428M15Rik MGI:MGI:1924280 +77031 Slc9a8 MGI:MGI:1924281|Ensembl:ENSMUSG00000039463|Vega:OTTMUSG00000001141 +77032 Tstd3 MGI:MGI:1924282|Ensembl:ENSMUSG00000028251|Vega:OTTMUSG00000004737 +77034 2510039O18Rik MGI:MGI:1924284|Ensembl:ENSMUSG00000044496|Vega:OTTMUSG00000010678 +77035 Kdm8 MGI:MGI:1924285|Ensembl:ENSMUSG00000030752|Vega:OTTMUSG00000023596 +77036 1700109H08Rik MGI:MGI:1924286|Ensembl:ENSMUSG00000008307|Vega:OTTMUSG00000028546 +77037 Mrap MGI:MGI:1924287|Ensembl:ENSMUSG00000039956|Vega:OTTMUSG00000019934 +77038 Arfgap2 MGI:MGI:1924288|Ensembl:ENSMUSG00000027255|Vega:OTTMUSG00000014428 +77040 Atg16l1 MGI:MGI:1924290|Ensembl:ENSMUSG00000026289|Vega:OTTMUSG00000016467 +77041 Arsk MGI:MGI:1924291|Ensembl:ENSMUSG00000021592|Vega:OTTMUSG00000030517 +77042 Hyal4 MGI:MGI:1924292|Ensembl:ENSMUSG00000029680|Vega:OTTMUSG00000036569 +77043 4632433K11Rik MGI:MGI:1924293 +77044 Arid2 MGI:MGI:1924294|Ensembl:ENSMUSG00000033237|Vega:OTTMUSG00000017290 +77045 Bcl7a MGI:MGI:1924295|Ensembl:ENSMUSG00000029438|Vega:OTTMUSG00000026971 +77048 Cep83 MGI:MGI:1924298|Ensembl:ENSMUSG00000020024 +77049 4921528I07Rik MGI:MGI:1924299|Ensembl:ENSMUSG00000064299 +77053 Sun1 MGI:MGI:1924303|Ensembl:ENSMUSG00000036817|Vega:OTTMUSG00000025175 +77055 Krt76 MGI:MGI:1924305|Ensembl:ENSMUSG00000075402|Vega:OTTMUSG00000028008 +77056 Tmco4 MGI:MGI:1924306|Ensembl:ENSMUSG00000041143|Vega:OTTMUSG00000009903 +77057 Ston1 MGI:MGI:1924307|Ensembl:ENSMUSG00000033855|Vega:OTTMUSG00000033050 +77058 Ccdc183 MGI:MGI:1924308|Ensembl:ENSMUSG00000026940|Vega:OTTMUSG00000012249 +77059 4931408D14Rik MGI:MGI:1924309 +77062 5330422M15Rik MGI:MGI:1924312 +77063 5330425B07Rik MGI:MGI:1924313 +77065 Ints7 MGI:MGI:1924315|Ensembl:ENSMUSG00000037461|Vega:OTTMUSG00000051636 +77066 5930409G06Rik MGI:MGI:1924316 +77068 5930436O19Rik MGI:MGI:1924318 +77069 6030400A10Rik MGI:MGI:1924319 +77070 6030442H21Rik MGI:MGI:1924320 +77072 6720420G18Rik MGI:MGI:1924322 +77077 9030205G03Rik MGI:MGI:1924327 +77080 9230110F15Rik MGI:MGI:1924330|Ensembl:ENSMUSG00000047980|Vega:OTTMUSG00000044687 +77082 2900011L18Rik MGI:MGI:1924332 +77083 3010023C09Rik MGI:MGI:1924333 +77087 Ankrd11 MGI:MGI:1924337|Ensembl:ENSMUSG00000035569|Vega:OTTMUSG00000037981 +77088 3010031K01Rik MGI:MGI:1924338 +77089 5730564C23Rik MGI:MGI:1924339 +77090 Ocel1 MGI:MGI:1924340|Ensembl:ENSMUSG00000002396|Vega:OTTMUSG00000022215 +77093 A330094K24Rik MGI:MGI:1924343 +77095 D330022H12Rik MGI:MGI:1924345 +77096 5730585A16Rik MGI:MGI:1924346 +77097 Tanc2 MGI:MGI:2444121|Ensembl:ENSMUSG00000053580|Vega:OTTMUSG00000002986 +77103 5330439A09Rik MGI:MGI:1924353 +77106 Tmem181a MGI:MGI:1924356|Ensembl:ENSMUSG00000038141|Vega:OTTMUSG00000052561 +77110 Gpbp1l1 MGI:MGI:1924360|Ensembl:ENSMUSG00000034042|Vega:OTTMUSG00000009410 +77112 5930427J20Rik MGI:MGI:1924362 +77113 Klhl2 MGI:MGI:1924363|Ensembl:ENSMUSG00000031605|Vega:OTTMUSG00000061229 +77114 Gm9735 MGI:MGI:3805013 +77115 6030451C04Rik MGI:MGI:1924365 +77116 Mtmr2 MGI:MGI:1924366|Ensembl:ENSMUSG00000031918|Vega:OTTMUSG00000032802 +77117 Zfp934 MGI:MGI:1924367|Ensembl:ENSMUSG00000074865 +77118 6720490N10Rik MGI:MGI:1924368 +77119 7630403G23Rik MGI:MGI:1924369|Ensembl:ENSMUSG00000098758 +77120 9030201C23Rik MGI:MGI:1924370 +77123 9130214F15Rik MGI:MGI:1924373 +77124 9130221H12Rik MGI:MGI:1924374|Ensembl:ENSMUSG00000090330 +77125 Il33 MGI:MGI:1924375|Ensembl:ENSMUSG00000024810|Vega:OTTMUSG00000028342 +77126 9930101C24Rik MGI:MGI:1924376 +77127 A930001A20Rik MGI:MGI:1924377|Ensembl:ENSMUSG00000098008 +77128 Crebrf MGI:MGI:1924378|Ensembl:ENSMUSG00000048249|Vega:OTTMUSG00000033233 +77132 2810433D01Rik MGI:MGI:1924382 +77134 Hnrnpa0 MGI:MGI:1924384|Ensembl:ENSMUSG00000007836 +77135 3010033E01Rik MGI:MGI:1924385 +77166 8030423J24Rik MGI:MGI:1924416|Ensembl:ENSMUSG00000021600 +77167 8030476L19Rik MGI:MGI:1924417 +77168 8030450C14Rik MGI:MGI:1924418 +77169 8030459D09Rik MGI:MGI:1924419 +77171 8030455M16Rik MGI:MGI:1924421|Ensembl:ENSMUSG00000110507 +77173 8030443G20Rik MGI:MGI:1924423|Ensembl:ENSMUSG00000086483 +77188 A430105D02Rik MGI:MGI:1924438 +77189 A430105J06Rik MGI:MGI:1924439 +77191 A930005N03Rik MGI:MGI:1924441 +77193 A930030B08Rik MGI:MGI:1924443 +77198 4930407I19Rik MGI:MGI:1924448|Ensembl:ENSMUSG00000112210 +77200 5430403G16Rik MGI:MGI:1924450 +77201 8030431A06Rik MGI:MGI:1924451 +77203 9330159N22Rik MGI:MGI:1924453 +77207 8030425K09Rik MGI:MGI:1924457 +77209 8030453O22Rik MGI:MGI:1924459 +77210 8030448I15Rik MGI:MGI:1924460 +77215 Krtap5-3 MGI:MGI:1924465|Ensembl:ENSMUSG00000046248|Vega:OTTMUSG00000045004 +77216 A930002H02Rik MGI:MGI:1924466 +77219 Ptgr2 MGI:MGI:1916372|Ensembl:ENSMUSG00000072946|Vega:OTTMUSG00000032610 +77220 Tmem200a MGI:MGI:1924470|Ensembl:ENSMUSG00000049420 +77223 4930407G08Rik MGI:MGI:1924473|Ensembl:ENSMUSG00000086713 +77225 9330161L09Rik MGI:MGI:1924475 +77226 9330169L03Rik MGI:MGI:1924476 +77241 9430013L14Rik MGI:MGI:1924491 +77244 9430012M22Rik MGI:MGI:1924494 +77245 9330199C07Rik MGI:MGI:1924495 +77246 9330177L23Rik MGI:MGI:1924496 +77247 9430006E15Rik MGI:MGI:1924497 +77248 9430014N10Rik MGI:MGI:1924498 +77250 9430019H13Rik MGI:MGI:1924500 +77251 9430020M11Rik MGI:MGI:1924501 +77252 9430038I01Rik MGI:MGI:1924502|Ensembl:ENSMUSG00000040139|Vega:OTTMUSG00000029134 +77253 9430031K09Rik MGI:MGI:1924503 +77254 Yif1b MGI:MGI:1924504|Ensembl:ENSMUSG00000030588|Vega:OTTMUSG00000025025 +77255 9430014F16Rik MGI:MGI:1924505 +77257 9430024E24Rik MGI:MGI:1924507 +77258 9430014K20Rik MGI:MGI:1924508 +77264 Zfp142 MGI:MGI:1924514|Ensembl:ENSMUSG00000026135|Vega:OTTMUSG00000021744 +77265 9430002A10Rik MGI:MGI:1924515 +77266 9430013L17Rik MGI:MGI:1924516 +77267 9430018C23Rik MGI:MGI:1924517 +77269 9430019J16Rik MGI:MGI:1924519 +77270 9430007M09Rik MGI:MGI:1924520 +77271 9430024F10Rik MGI:MGI:1924521 +77272 9430027B09Rik MGI:MGI:1924522 +77276 9430022A06Rik MGI:MGI:1924526 +77278 9430024C03Rik MGI:MGI:1924528 +77279 9430019C24Rik MGI:MGI:1924529 +77280 9430040K09Rik MGI:MGI:1924530 +77283 9430022A07Rik MGI:MGI:1924533 +77285 9430037O13Rik MGI:MGI:1924535 +77286 Nkrf MGI:MGI:1924536|Ensembl:ENSMUSG00000044149|Vega:OTTMUSG00000017111 +77288 9430021M05Rik MGI:MGI:1924538 +77289 9430034F23Rik MGI:MGI:1924539 +77290 9430078K24Rik MGI:MGI:1924540|Ensembl:ENSMUSG00000112765 +77291 9430079G20Rik MGI:MGI:1924541 +77294 9430064K01Rik MGI:MGI:1924544 +77296 Fam162b MGI:MGI:1924546|Ensembl:ENSMUSG00000019909 +77300 Raph1 MGI:MGI:1924550|Ensembl:ENSMUSG00000026014|Vega:OTTMUSG00000002211 +77301 9430031J08Rik MGI:MGI:1924551 +77302 9430078K10Rik MGI:MGI:1924552 +77304 9430068D22Rik MGI:MGI:1924554 +77305 Wdr82 MGI:MGI:1924555|Ensembl:ENSMUSG00000020257|Vega:OTTMUSG00000049420 +77311 C030011I16Rik MGI:MGI:1924561 +77312 C030010L15Rik MGI:MGI:1924562 +77315 C030008P14Rik MGI:MGI:1924565 +77316 C030011L09Rik MGI:MGI:1924566 +77318 Ankrd55 MGI:MGI:1924568|Ensembl:ENSMUSG00000049985 +77319 C030007D22Rik MGI:MGI:1924569 +77323 9430041J12Rik MGI:MGI:1924573|Ensembl:ENSMUSG00000086155 +77328 C030009O12Rik MGI:MGI:1924578 +77329 C030010C08Rik MGI:MGI:1924579 +77330 C030011G24Rik MGI:MGI:1924580 +77331 C030007H22Rik MGI:MGI:1924581|Ensembl:ENSMUSG00000099938 +77332 C030012D19Rik MGI:MGI:1924582 +77333 C030007I01Rik MGI:MGI:1924583 +77336 9430030N17Rik MGI:MGI:1924586 +77337 Akr1c21 MGI:MGI:1924587|Ensembl:ENSMUSG00000021207|Vega:OTTMUSG00000027696 +77338 9430052A13Rik MGI:MGI:1924588 +77339 9430051O21Rik MGI:MGI:1924589 +77340 9530022L04Rik MGI:MGI:1924590 +77341 9530026F06Rik MGI:MGI:1924591|Ensembl:ENSMUSG00000085447 +77347 B230204H03Rik MGI:MGI:1924597 +77352 Axdnd1 MGI:MGI:1924602|Ensembl:ENSMUSG00000026601|Vega:OTTMUSG00000023021 +77353 9430095M17Rik MGI:MGI:1924603 +77358 9430069I07Rik MGI:MGI:1924608|Ensembl:ENSMUSG00000094447 +77359 9430063H18Rik MGI:MGI:1924609 +77361 9430085M18Rik MGI:MGI:1924611 +77362 9430093N23Rik MGI:MGI:1924612 +77363 9530004P13Rik MGI:MGI:1924613 +77365 9430083B18Rik MGI:MGI:1924615 +77366 9530002O20Rik MGI:MGI:1924616 +77369 9430087D07Rik MGI:MGI:1924619 +77370 9530004M14Rik MGI:MGI:1924620 +77371 Sec24a MGI:MGI:1924621|Ensembl:ENSMUSG00000036391|Vega:OTTMUSG00000005603 +77374 9430082L08Rik MGI:MGI:1924624 +77375 9430085L16Rik MGI:MGI:1924625 +77376 C030013D06Rik MGI:MGI:1924626 +77378 C030026M15Rik MGI:MGI:1924628 +77381 C030014I23Rik MGI:MGI:1924631 +77382 C030018K13Rik MGI:MGI:1924632|Ensembl:ENSMUSG00000105352 +77383 C030029H02Rik MGI:MGI:1924633|Ensembl:ENSMUSG00000110027 +77384 C030017D09Rik MGI:MGI:1924634 +77388 C030018G05Rik MGI:MGI:1924638 +77389 C030032F19Rik MGI:MGI:1924639 +77390 9430099N05Rik MGI:MGI:1924640 +77391 9530003O04Rik MGI:MGI:1924641 +77393 9530006C21Rik MGI:MGI:1924643 +77394 9530025H10Rik MGI:MGI:1924644 +77395 9530018H14Rik MGI:MGI:1924645 +77397 9530003J23Rik MGI:MGI:1924647|Ensembl:ENSMUSG00000020177|Vega:OTTMUSG00000027778 +77398 9530014B07Rik MGI:MGI:1924648|Ensembl:ENSMUSG00000113599 +77400 9530006O14Rik MGI:MGI:1924650 +77401 9430087J23Rik MGI:MGI:1924651 +77402 9530018F02Rik MGI:MGI:1924652 +77406 9530004M16Rik MGI:MGI:1924656 +77407 Rab35 MGI:MGI:1924657|Ensembl:ENSMUSG00000029518|Vega:OTTMUSG00000014704 +77408 9530013L04Rik MGI:MGI:1924658 +77410 9530027D23Rik MGI:MGI:1924660 +77411 Esrp2 MGI:MGI:1924661|Ensembl:ENSMUSG00000084128|Vega:OTTMUSG00000022556 +77414 C030013G03Rik MGI:MGI:1924664 +77415 C030015E24Rik MGI:MGI:1924665 +77417 C030013C21Rik MGI:MGI:1924667|Ensembl:ENSMUSG00000085078 +77418 C030015A19Rik MGI:MGI:1924668 +77420 C030032G21Rik MGI:MGI:1924670 +77421 C030013E06Rik MGI:MGI:1924671 +77422 C330018D20Rik MGI:MGI:1924672|Ensembl:ENSMUSG00000024592|Vega:OTTMUSG00000033171 +77424 Spinkl MGI:MGI:1924674|Ensembl:ENSMUSG00000053729 +77425 9430081G06Rik MGI:MGI:1924675 +77426 9430099H24Rik MGI:MGI:1924676 +77427 9430092D12Rik MGI:MGI:1924677 +77428 9430083A17Rik MGI:MGI:1924678 +77430 9430081H08Rik MGI:MGI:1924680 +77431 9530001D17Rik MGI:MGI:1924681 +77432 9530002B09Rik MGI:MGI:1924682|Ensembl:ENSMUSG00000023263|Vega:OTTMUSG00000008879 +77433 Redrum MGI:MGI:1924683 +77435 9430076D03Rik MGI:MGI:1924685 +77436 9530001N24Rik MGI:MGI:1924686 +77437 9430087B13Rik MGI:MGI:1924687 +77439 9530025L08Rik MGI:MGI:1924689 +77440 9430087N24Rik MGI:MGI:1924690 +77441 9430099M06Rik MGI:MGI:1924691 +77442 9530020I12Rik MGI:MGI:1924692|Ensembl:ENSMUSG00000112041 +77445 9530015I06Rik MGI:MGI:1924695 +77446 Heg1 MGI:MGI:1924696|Ensembl:ENSMUSG00000075254|Vega:OTTMUSG00000027314 +77447 9430096G21Rik MGI:MGI:1924697 +77449 9530007D14Rik MGI:MGI:1924699 +77450 9530013E20Rik MGI:MGI:1924700 +77451 9530022J15Rik MGI:MGI:1924701 +77453 Dmrta2os MGI:MGI:1924703|Ensembl:ENSMUSG00000085256 +77462 Tmem116 MGI:MGI:1924712|Ensembl:ENSMUSG00000029452|Vega:OTTMUSG00000023447 +77463 C030014O09Rik MGI:MGI:1924713 +77465 C030027H14Rik MGI:MGI:1924715 +77468 C030032O16Rik MGI:MGI:1924718 +77469 C030034E14Rik MGI:MGI:1924719 +77470 C030026O17Rik MGI:MGI:1924720 +77472 C030024C20Rik MGI:MGI:1924722 +77475 C030037F17Rik MGI:MGI:1924725 +77476 C030046M01Rik MGI:MGI:1924726 +77480 Kidins220 MGI:MGI:1924730|Ensembl:ENSMUSG00000036333 +77481 C030048H21Rik MGI:MGI:1924731 +77482 C030041M11Rik MGI:MGI:1924732 +77485 Stk31 MGI:MGI:1924735|Ensembl:ENSMUSG00000023403|Vega:OTTMUSG00000036462 +77487 C330004M20Rik MGI:MGI:1924737 +77490 E130218I03Rik MGI:MGI:3528958|Ensembl:ENSMUSG00000086322|Vega:OTTMUSG00000010567 +77492 8030456M14Rik MGI:MGI:1924742 +77495 8030444G23Rik MGI:MGI:1924745 +77505 Dnhd1 MGI:MGI:1924755|Ensembl:ENSMUSG00000030882|Vega:OTTMUSG00000025560 +77506 8030497O21Rik MGI:MGI:1924756 +77508 9330118I20Rik MGI:MGI:1924758 +77509 9330153N18Rik MGI:MGI:1924759 +77510 9330179A15Rik MGI:MGI:1924760 +77511 9330185C12Rik MGI:MGI:1924761 +77516 9330198N18Rik MGI:MGI:1924766 +77518 9330179C17Rik MGI:MGI:1924768 +77519 Zfp266 MGI:MGI:1924769|Ensembl:ENSMUSG00000060510|Vega:OTTMUSG00000037612 +77521 Mtus2 MGI:MGI:1915388|Ensembl:ENSMUSG00000029651|Vega:OTTMUSG00000025701 +77522 Tmem213 MGI:MGI:1924772|Ensembl:ENSMUSG00000029829|Vega:OTTMUSG00000056248 +77524 C030017B01Rik MGI:MGI:1924774 +77525 C030013C02Rik MGI:MGI:1924775 +77526 C030015D21Rik MGI:MGI:1924776 +77528 C030014A21Rik MGI:MGI:1924778 +77529 C030014C12Rik MGI:MGI:1924779 +77531 Anks1b MGI:MGI:1924781|Ensembl:ENSMUSG00000058589|Vega:OTTMUSG00000043484 +77532 Jrkl MGI:MGI:1924782|Ensembl:ENSMUSG00000079083|Vega:OTTMUSG00000062361 +77533 C030034I22Rik MGI:MGI:1924783 +77538 C330004P14Rik MGI:MGI:1924788|Ensembl:ENSMUSG00000112227 +77543 8030442B05Rik MGI:MGI:1924793|Ensembl:ENSMUSG00000102674 +77544 8030479D07Rik MGI:MGI:1924794 +77546 8030443L12Rik MGI:MGI:1924796 +77547 8030498B09Rik MGI:MGI:1924797 +77548 8030487O14Rik MGI:MGI:1924798 +77549 9330109K16Rik MGI:MGI:1924799 +77552 Shisa4 MGI:MGI:1924802|Ensembl:ENSMUSG00000041889|Vega:OTTMUSG00000026808 +77554 9330154F10Rik MGI:MGI:1924804 +77557 9330182L19Rik MGI:MGI:1924807 +77558 9330179D12Rik MGI:MGI:1924808|Ensembl:ENSMUSG00000097166 +77559 Agl MGI:MGI:1924809|Ensembl:ENSMUSG00000033400|Vega:OTTMUSG00000034170 +77560 9330198I05Rik MGI:MGI:1924810 +77569 Limch1 MGI:MGI:1924819|Ensembl:ENSMUSG00000037736|Vega:OTTMUSG00000028044 +77570 3930401B19Rik MGI:MGI:1924820 +77573 Vps33a MGI:MGI:1924823|Ensembl:ENSMUSG00000029434|Vega:OTTMUSG00000054672 +77574 Tcaf1 MGI:MGI:1914665|Ensembl:ENSMUSG00000036667|Vega:OTTMUSG00000027060 +77577 Spns3 MGI:MGI:1924827|Ensembl:ENSMUSG00000020798|Vega:OTTMUSG00000008086 +77578 Bcl9 MGI:MGI:1924828|Ensembl:ENSMUSG00000038256|Vega:OTTMUSG00000022435 +77579 Myh10 MGI:MGI:1930780|Ensembl:ENSMUSG00000020900|Vega:OTTMUSG00000005955 +77580 5730596B20Rik MGI:MGI:1924830|Ensembl:ENSMUSG00000056468 +77582 Mboat7 MGI:MGI:1924832|Ensembl:ENSMUSG00000035596|Vega:OTTMUSG00000023042 +77583 Notum MGI:MGI:1924833|Ensembl:ENSMUSG00000042988|Vega:OTTMUSG00000004091 +77590 Chst15 MGI:MGI:1924840|Ensembl:ENSMUSG00000030930|Vega:OTTMUSG00000023015 +77591 Ddx10 MGI:MGI:1924841|Ensembl:ENSMUSG00000053289|Vega:OTTMUSG00000063123 +77592 4931406H21Rik MGI:MGI:1924842 +77593 Usp45 MGI:MGI:101850|Ensembl:ENSMUSG00000040455|Vega:OTTMUSG00000004738 +77594 4930552P12Rik MGI:MGI:1924844|Ensembl:ENSMUSG00000097632 +77595 Nup210l MGI:MGI:1924845|Ensembl:ENSMUSG00000027939|Vega:OTTMUSG00000052889 +77596 Adgrf1 MGI:MGI:1924846|Ensembl:ENSMUSG00000041293|Vega:OTTMUSG00000025266 +77598 5830406C21Rik MGI:MGI:1924848 +77599 5830420C07Rik MGI:MGI:1924849 +77602 C430050I21Rik MGI:MGI:1924852 +77604 Rbm12b2 MGI:MGI:1924854|Ensembl:ENSMUSG00000052137|Vega:OTTMUSG00000004572 +77605 H2afv MGI:MGI:1924855|Ensembl:ENSMUSG00000041126|Vega:OTTMUSG00000005109 +77608 C330004N01Rik MGI:MGI:1924858 +77609 Ccdc151 MGI:MGI:1924859|Ensembl:ENSMUSG00000039632|Vega:OTTMUSG00000062325 +77610 C330002G04Rik MGI:MGI:1924860 +77612 C030038I04Rik MGI:MGI:1924862 +77613 Prss36 MGI:MGI:1924863|Ensembl:ENSMUSG00000070371|Vega:OTTMUSG00000031084 +77614 C030044M21Rik MGI:MGI:1924864 +77618 C030047K22Rik MGI:MGI:1924868 +77619 Prelid2 MGI:MGI:1924869|Ensembl:ENSMUSG00000056671 +77620 C030045M22Rik MGI:MGI:1924870 +77621 C330008A17Rik MGI:MGI:1924871 +77622 Apex2 MGI:MGI:1924872|Ensembl:ENSMUSG00000025269|Vega:OTTMUSG00000019152 +77623 C430039J16Rik MGI:MGI:1924873 +77625 C530007A02Rik MGI:MGI:1924875 +77626 Smpd4 MGI:MGI:1924876|Ensembl:ENSMUSG00000005899|Vega:OTTMUSG00000035764 +77627 Efcab6 MGI:MGI:1924877|Ensembl:ENSMUSG00000022441|Vega:OTTMUSG00000026031 +77628 4930544N03Rik MGI:MGI:1924878 +77629 Sphkap MGI:MGI:1924879|Ensembl:ENSMUSG00000026163|Vega:OTTMUSG00000030288 +77630 Prdm8 MGI:MGI:1924880|Ensembl:ENSMUSG00000035456|Vega:OTTMUSG00000053329 +77631 4930554H23Rik MGI:MGI:1924881|Ensembl:ENSMUSG00000097682 +77632 Pramef12 MGI:MGI:1924882|Ensembl:ENSMUSG00000028591|Vega:OTTMUSG00000010551 +77633 4930594C11Rik MGI:MGI:1924883|Ensembl:ENSMUSG00000103948 +77634 Snapc3 MGI:MGI:1916338|Ensembl:ENSMUSG00000028483|Vega:OTTMUSG00000000033 +77637 C030044C18Rik MGI:MGI:1924887 +77639 C030041B07Rik MGI:MGI:1924889 +77640 C030039E19Rik MGI:MGI:1924890 +77642 C330001P17Rik MGI:MGI:1924892 +77644 C330007P06Rik MGI:MGI:1924894|Ensembl:ENSMUSG00000006423|Vega:OTTMUSG00000017108 +77645 Ptprtos MGI:MGI:1924895|Ensembl:ENSMUSG00000084919 +77646 C030043A13Rik MGI:MGI:1924896 +77647 Trat1 MGI:MGI:1924897|Ensembl:ENSMUSG00000030775 +77651 C430039J01Rik MGI:MGI:1924901 +77652 Zfp955a MGI:MGI:4834570|Ensembl:ENSMUSG00000094441 +77654 C430049A07Rik MGI:MGI:1924904 +77656 C430045I18Rik MGI:MGI:1924906 +77661 1520401O13Rik MGI:MGI:1924911 +77662 9030218A15Rik MGI:MGI:1924912 +77665 9030204H09Rik MGI:MGI:1924915|Ensembl:ENSMUSG00000086449 +77667 9130231A04Rik MGI:MGI:1924917 +77668 9130209A04Rik MGI:MGI:1924918 +77669 Arhgef38 MGI:MGI:1924919|Ensembl:ENSMUSG00000040969|Vega:OTTMUSG00000030538 +77673 Defb41 MGI:MGI:1924923|Ensembl:ENSMUSG00000067773|Vega:OTTMUSG00000020948 +77674 Defb12 MGI:MGI:1924924|Ensembl:ENSMUSG00000043787|Vega:OTTMUSG00000020595 +77675 5033406O09Rik MGI:MGI:1923205|Ensembl:ENSMUSG00000113769 +77680 9230109C02Rik MGI:MGI:1924930 +77682 9230102O04Rik MGI:MGI:1924932|Ensembl:ENSMUSG00000079602 +77683 Ehmt1 MGI:MGI:1924933|Ensembl:ENSMUSG00000036893|Vega:OTTMUSG00000012294 +77684 Bsph2 MGI:MGI:1924934|Ensembl:ENSMUSG00000078800|Vega:OTTMUSG00000056206 +77688 9230104K21Rik MGI:MGI:1924938 +77696 6720484G13Rik MGI:MGI:1924946 +77697 Mmab MGI:MGI:1924947|Ensembl:ENSMUSG00000029575|Vega:OTTMUSG00000014461 +77698 9230110I02Rik MGI:MGI:1924948 +77699 9030616G12Rik MGI:MGI:1924949|Ensembl:ENSMUSG00000097691 +77700 9130208D14Rik MGI:MGI:1924950 +77701 Lcn12 MGI:MGI:1924951|Ensembl:ENSMUSG00000026943|Vega:OTTMUSG00000012121 +77702 9130201A16Rik MGI:MGI:1924952 +77703 9230106L01Rik MGI:MGI:1924953 +77704 Lcn9 MGI:MGI:1924954|Ensembl:ENSMUSG00000023210|Vega:OTTMUSG00000012630 +77705 9230104L09Rik MGI:MGI:1924955|Ensembl:ENSMUSG00000027446|Vega:OTTMUSG00000015720 +77706 Abcb5 MGI:MGI:1924956|Ensembl:ENSMUSG00000072791|Vega:OTTMUSG00000036992 +77707 9130604C24Rik MGI:MGI:1924957 +77708 9130223C08Rik MGI:MGI:1924958 +77710 4831407H17Rik MGI:MGI:1924960 +77717 6030408B16Rik MGI:MGI:1924967|Ensembl:ENSMUSG00000075408 +77719 6030458A19Rik MGI:MGI:1924969 +77720 6720454L20Rik MGI:MGI:1924970 +77721 Mrps5 MGI:MGI:1924971|Ensembl:ENSMUSG00000027374|Vega:OTTMUSG00000016028 +77723 Dnah2os MGI:MGI:1924973 +77724 6030460B20Rik MGI:MGI:1924974 +77726 6030492E11Rik MGI:MGI:1924976 +77727 6030468B19Rik MGI:MGI:1924977|Ensembl:ENSMUSG00000025573|Vega:OTTMUSG00000025960 +77729 6720451E02Rik MGI:MGI:1924979 +77731 6720477C19Rik MGI:MGI:1924981 +77733 Rnf170 MGI:MGI:1924983|Ensembl:ENSMUSG00000013878|Vega:OTTMUSG00000023970 +77736 6720460K10Rik MGI:MGI:1924986 +77738 6720469O03Rik MGI:MGI:1924988 +77739 Adamtsl1 MGI:MGI:1924989|Ensembl:ENSMUSG00000066113|Vega:OTTMUSG00000007395 +77740 6720432D03Rik MGI:MGI:1924990|Ensembl:ENSMUSG00000111511 +77741 6720483E21Rik MGI:MGI:1924991|Ensembl:ENSMUSG00000097934 +77744 Bora MGI:MGI:1924994|Ensembl:ENSMUSG00000022070 +77746 9930120I10Rik MGI:MGI:1924996 +77747 A230102O21Rik MGI:MGI:1924997 +77748 9230111E07Rik MGI:MGI:1924998 +77751 9230118N17Rik MGI:MGI:1925001 +77753 A230103O09Rik MGI:MGI:1925003 +77756 A230101C19Rik MGI:MGI:1925006 +77760 A230106O10Rik MGI:MGI:1925010 +77761 9230118N01Rik MGI:MGI:1925011 +77762 9930111H07Rik MGI:MGI:1925012|Ensembl:ENSMUSG00000100217 +77763 Gm9736 MGI:MGI:3842085 +77766 Elp4 MGI:MGI:1925016|Ensembl:ENSMUSG00000027167|Vega:OTTMUSG00000015120 +77767 Ermn MGI:MGI:1925017|Ensembl:ENSMUSG00000026830|Vega:OTTMUSG00000012597 +77768 A430105P17Rik MGI:MGI:1925018 +77770 A930008L05Rik MGI:MGI:1925020 +77771 Csrnp3 MGI:MGI:1925021|Ensembl:ENSMUSG00000044647|Vega:OTTMUSG00000012965 +77772 Dcst1 MGI:MGI:1925022|Ensembl:ENSMUSG00000042672|Vega:OTTMUSG00000022079 +77775 A430103D13Rik MGI:MGI:1925025 +77776 A430106A03Rik MGI:MGI:1925026 +77777 Ulbp1 MGI:MGI:1925027|Ensembl:ENSMUSG00000079685 +77778 A430102O06Rik MGI:MGI:1925028 +77779 A930007I19Rik MGI:MGI:1925029|Ensembl:ENSMUSG00000097855 +77781 Epm2aip1 MGI:MGI:1925031|Ensembl:ENSMUSG00000046785|Vega:OTTMUSG00000030275 +77782 Polq MGI:MGI:2155399|Ensembl:ENSMUSG00000034206|Vega:OTTMUSG00000043424 +77783 A930008B05Rik MGI:MGI:1925033 +77788 A430110A21Rik MGI:MGI:1925038 +77789 A930007D18Rik MGI:MGI:1925039 +77790 A930006J02Rik MGI:MGI:1925040 +77791 A930003G23Rik MGI:MGI:1925041 +77792 A930003K04Rik MGI:MGI:1925042 +77794 Adamtsl2 MGI:MGI:1925044|Ensembl:ENSMUSG00000036040|Vega:OTTMUSG00000011845 +77795 A930010G16Rik MGI:MGI:1925045 +77796 A930009E05Rik MGI:MGI:1925046 +77798 A930009A15Rik MGI:MGI:1925048|Ensembl:ENSMUSG00000092210|Vega:OTTMUSG00000037607 +77799 Sla2 MGI:MGI:1925049|Ensembl:ENSMUSG00000027636|Vega:OTTMUSG00000016076 +77800 4933406J10Rik MGI:MGI:1921308|Ensembl:ENSMUSG00000086690 +77801 A930015P04Rik MGI:MGI:1925051 +77802 A930026C06Rik MGI:MGI:1925052 +77803 Fam159b MGI:MGI:1925053|Ensembl:ENSMUSG00000042655 +77804 A930019H14Rik MGI:MGI:1925054 +77805 Esco1 MGI:MGI:1925055|Ensembl:ENSMUSG00000024293|Vega:OTTMUSG00000024447 +77806 A930019D19Rik MGI:MGI:1925056|Ensembl:ENSMUSG00000085958 +77807 A930025H08Rik MGI:MGI:1925057 +77808 Gm44196 MGI:MGI:5690588 +77809 Lrrc42 MGI:MGI:1925059|Ensembl:ENSMUSG00000028617|Vega:OTTMUSG00000008593 +77810 A930015D03Rik MGI:MGI:1925060 +77812 A930014D08Rik MGI:MGI:1925062 +77813 A930012N16Rik MGI:MGI:1925063 +77815 A930024O17Rik MGI:MGI:1925065 +77816 A930013N22Rik MGI:MGI:1925066 +77817 A930018O16Rik MGI:MGI:1925067 +77820 A930028O11Rik MGI:MGI:1925070 +77821 A930031G03Rik MGI:MGI:1925071 +77822 Ube4bos1 MGI:MGI:1925072 +77825 A930027M08Rik MGI:MGI:1925075 +77827 Krba1 MGI:MGI:1925077|Ensembl:ENSMUSG00000042810|Vega:OTTMUSG00000024285 +77829 A930036K24Rik MGI:MGI:1925079 +77830 A930033M24Rik MGI:MGI:1925080 +77832 Tchp MGI:MGI:1925082|Ensembl:ENSMUSG00000002486|Vega:OTTMUSG00000014526 +77833 A930032L01Rik MGI:MGI:1925083 +77834 A930041H05Rik MGI:MGI:1925084 +77835 A930031H19Rik MGI:MGI:1925085|Ensembl:ENSMUSG00000086262 +77836 Mlana MGI:MGI:108454|Ensembl:ENSMUSG00000024806 +77837 A930035F09Rik MGI:MGI:1925087 +77838 A930036M01Rik MGI:MGI:1925088 +77839 A930036A04Rik MGI:MGI:1925089 +77841 Far2os2 MGI:MGI:1925091 +77842 B230112G18Rik MGI:MGI:1925092 +77843 Rapgef4it MGI:MGI:1925093 +77846 B230112J18Rik MGI:MGI:1925096|Ensembl:ENSMUSG00000086715 +77847 B230104F01Rik MGI:MGI:1925097 +77849 B430319H21Rik MGI:MGI:1925099 +77850 B830007D08Rik MGI:MGI:1925100 +77851 D730044K07Rik MGI:MGI:1925101 +77852 D730047P14Rik MGI:MGI:1925102 +77853 Msl2 MGI:MGI:1925103|Ensembl:ENSMUSG00000066415|Vega:OTTMUSG00000048624 +77854 E130111B04Rik MGI:MGI:1925104 +77855 D730045A05Rik MGI:MGI:1925105|Ensembl:ENSMUSG00000090263 +77857 9430065F17Rik MGI:MGI:1924606|Ensembl:ENSMUSG00000097360 +77859 D730050C22Rik MGI:MGI:1925109 +77860 D730047E02Rik MGI:MGI:1925110 +77862 Thyn1 MGI:MGI:1925112|Ensembl:ENSMUSG00000035443|Vega:OTTMUSG00000062681 +77863 D730048M23Rik MGI:MGI:1925113 +77864 Ypel2 MGI:MGI:1925114|Ensembl:ENSMUSG00000018427|Vega:OTTMUSG00000001220 +77866 E130102H24Rik MGI:MGI:1925116|Ensembl:ENSMUSG00000086782 +77867 D730045B01Rik MGI:MGI:1925117 +77869 E130112B07Rik MGI:MGI:1925119 +77870 E130116L18Rik MGI:MGI:1925120 +77875 Cyp4f41-ps MGI:MGI:1925125 +77876 6030442K20Rik MGI:MGI:1925126 +77877 6030458C11Rik MGI:MGI:1925127|Ensembl:ENSMUSG00000022195 +77878 6030440G07Rik MGI:MGI:1925128|Ensembl:ENSMUSG00000113056 +77879 6030446M11Rik MGI:MGI:1925129 +77880 6030442E23Rik MGI:MGI:1925130 +77881 6030458E02Rik MGI:MGI:1925131 +77883 6030498E09Rik MGI:MGI:1925133|Ensembl:ENSMUSG00000051361|Vega:OTTMUSG00000017240 +77884 6720427H10Rik MGI:MGI:1925134 +77887 6720454L07Rik MGI:MGI:1925137 +77889 Lbh MGI:MGI:1925139|Ensembl:ENSMUSG00000024063|Vega:OTTMUSG00000028495 +77890 6720407P12Rik MGI:MGI:1925140 +77891 Ube2s MGI:MGI:1925141|Ensembl:ENSMUSG00000060860|Vega:OTTMUSG00000058431 +77892 6720418B01Rik MGI:MGI:1925142 +77896 6720475M21Rik MGI:MGI:1925146 +77898 6720482G16Rik MGI:MGI:1925148 +77899 6720470G18Rik MGI:MGI:1925149 +77900 6720473M11Rik MGI:MGI:1925150 +77904 9230113A04Rik MGI:MGI:1925154 +77905 Fate1 MGI:MGI:1925155|Ensembl:ENSMUSG00000053593|Vega:OTTMUSG00000017817 +77908 9230113P08Rik MGI:MGI:1925158|Ensembl:ENSMUSG00000078934|Vega:OTTMUSG00000042023 +77911 9230118H08Rik MGI:MGI:1925161 +77913 A030003K21Rik MGI:MGI:1925163 +77914 Krtap17-1 MGI:MGI:1925164|Ensembl:ENSMUSG00000078252|Vega:OTTMUSG00000002175 +77917 A030014E15Rik MGI:MGI:1925167 +77918 Krtap19-3 MGI:MGI:1925168|Ensembl:ENSMUSG00000060469 +77919 A330102K18Rik MGI:MGI:1925169 +77920 A330102I10Rik MGI:MGI:1925170|Ensembl:ENSMUSG00000086363 +77921 A030005K14Rik MGI:MGI:1925171 +77922 A030005L19Rik MGI:MGI:1925172 +77923 A330107A15Rik MGI:MGI:1925173 +77924 A430102A20Rik MGI:MGI:1925174 +77925 A430102K17Rik MGI:MGI:1925175 +77929 Yipf6 MGI:MGI:1925179|Ensembl:ENSMUSG00000047694|Vega:OTTMUSG00000018060 +77934 A430106F12Rik MGI:MGI:1925184 +77937 A930005C09Rik MGI:MGI:1925187 +77938 Fam53b MGI:MGI:1925188|Ensembl:ENSMUSG00000030956|Vega:OTTMUSG00000023048 +77940 A930004D18Rik MGI:MGI:1925190|Ensembl:ENSMUSG00000054057|Vega:OTTMUSG00000011458 +77941 A930001M01Rik MGI:MGI:1925191 +77942 A930006A01Rik MGI:MGI:1925192 +77945 Rpgrip1 MGI:MGI:1932134|Ensembl:ENSMUSG00000057132|Vega:OTTMUSG00000042894 +77947 A930014D07Rik MGI:MGI:1925197 +77948 A930016I07Rik MGI:MGI:1925198 +77949 A930011B18Rik MGI:MGI:1925199 +77951 Cyp20a1 MGI:MGI:1925201|Ensembl:ENSMUSG00000049439|Vega:OTTMUSG00000021516 +77953 A930011E06Rik MGI:MGI:1925203 +77954 A930012M21Rik MGI:MGI:1925204 +77956 A930026B05Rik MGI:MGI:1925206 +77958 A930023M06Rik MGI:MGI:1925208 +77961 A930027H12Rik MGI:MGI:1925211 +77963 Hook1 MGI:MGI:1925213|Ensembl:ENSMUSG00000028572|Vega:OTTMUSG00000008119 +77965 A930033C23Rik MGI:MGI:1925215 +77967 A930036I15Rik MGI:MGI:1925217 +77968 A930041D05Rik MGI:MGI:1925218 +77970 A930026I22Rik MGI:MGI:1925220 +77971 A930037O16Rik MGI:MGI:1925221 +77972 A930037G07Rik MGI:MGI:1925222 +77973 A930040O22Rik MGI:MGI:1925223 +77974 Rdh12 MGI:MGI:1925224|Ensembl:ENSMUSG00000021123|Vega:OTTMUSG00000027652 +77975 Tmem50b MGI:MGI:1925225|Ensembl:ENSMUSG00000022964|Vega:OTTMUSG00000019970 +77976 Nuak1 MGI:MGI:1925226|Ensembl:ENSMUSG00000020032|Vega:OTTMUSG00000022766 +77979 B230104C14Rik MGI:MGI:1925229 +77980 Sbf1 MGI:MGI:1925230|Ensembl:ENSMUSG00000036529|Vega:OTTMUSG00000032616 +77981 B230110C06Rik MGI:MGI:1925231 +77982 B230110G15Rik MGI:MGI:1925232|Ensembl:ENSMUSG00000100166 +77983 B230119M05Rik MGI:MGI:1925233|Ensembl:ENSMUSG00000087024 +77984 B230112I24Rik MGI:MGI:1925234 +77985 B230114A03Rik MGI:MGI:1925235 +77987 Ascc3 MGI:MGI:1925237|Ensembl:ENSMUSG00000038774 +77988 D730047N16Rik MGI:MGI:1925238 +77990 E130101E03Rik MGI:MGI:1925240 +77991 D730048M19Rik MGI:MGI:1925241 +77992 D730042M07Rik MGI:MGI:1925242 +77994 Mir99ahg MGI:MGI:1919929|Ensembl:ENSMUSG00000090386 +77995 E130102C15Rik MGI:MGI:1925245 +77996 Cutal MGI:MGI:1925246|Ensembl:ENSMUSG00000026870|Vega:OTTMUSG00000012021 +77998 Grifin MGI:MGI:1925248|Ensembl:ENSMUSG00000036586|Vega:OTTMUSG00000023977 +78002 E130101A01Rik MGI:MGI:1925252 +78004 Prr15 MGI:MGI:1925254|Ensembl:ENSMUSG00000045725|Vega:OTTMUSG00000057758 +78009 4930469B13Rik MGI:MGI:1925259 +78010 4930465I24Rik MGI:MGI:1925260 +78011 4930478K11Rik MGI:MGI:1925261 +78012 4930473D10Rik MGI:MGI:1925262 +78013 4930477O03Rik MGI:MGI:1925263 +78014 4930488B04Rik MGI:MGI:1925264 +78015 4930505K14Rik MGI:MGI:1925265|Ensembl:ENSMUSG00000085740 +78016 Ccdc150 MGI:MGI:1925266|Ensembl:ENSMUSG00000025983|Vega:OTTMUSG00000034794 +78017 4930504D19Rik MGI:MGI:1925267 +78019 4930519K11Rik MGI:MGI:1925269 +78021 4930513L16Rik MGI:MGI:1925271 +78023 4930529L06Rik MGI:MGI:1925273 +78024 4930543K20Rik MGI:MGI:1925274 +78025 4930540M03Rik MGI:MGI:1925275|Ensembl:ENSMUSG00000111299 +78026 4930539C01Rik MGI:MGI:1925276 +78027 4930535L15Rik MGI:MGI:1925277|Ensembl:ENSMUSG00000093619 +78028 4930545L08Rik MGI:MGI:1925278 +78029 4930538L07Rik MGI:MGI:1925279 +78030 4930527L19Rik MGI:MGI:1925280 +78031 4930547E08Rik MGI:MGI:1925281|Ensembl:ENSMUSG00000086687 +78032 LOC78032 - +78033 4930535G08Rik MGI:MGI:1925283 +78034 4930528H21Rik MGI:MGI:1925284|Ensembl:ENSMUSG00000107681 +78036 4930551I20Rik MGI:MGI:1925286 +78037 4930565M07Rik MGI:MGI:1925287 +78038 Mccc2 MGI:MGI:1925288|Ensembl:ENSMUSG00000021646 +78039 4930555M17Rik MGI:MGI:1925289|Ensembl:ENSMUSG00000093557 +78040 4930550L05Rik MGI:MGI:1925290 +78041 4930548G05Rik MGI:MGI:1925291 +78042 Lrrc75aos1 MGI:MGI:1925292 +78043 4930548J01Rik MGI:MGI:1925293 +78044 4930556A17Rik MGI:MGI:1925294 +78045 4930564I24Rik MGI:MGI:1925295 +78046 4930563H03Rik MGI:MGI:1925296 +78048 4930571O06Rik MGI:MGI:1925298 +78049 4930573O16Rik MGI:MGI:1925299 +78050 4930570N18Rik MGI:MGI:1925300 +78052 Tmem190 MGI:MGI:1925302|Ensembl:ENSMUSG00000013091|Vega:OTTMUSG00000058304 +78054 4930570G05Rik MGI:MGI:1925304 +78055 4930569F06Rik MGI:MGI:1925305 +78056 4930567K20Rik MGI:MGI:1925306|Ensembl:ENSMUSG00000112730 +78057 4930583I09Rik MGI:MGI:1925307|Ensembl:ENSMUSG00000024088 +78058 4930578E11Rik MGI:MGI:1925308 +78059 4930595L18Rik MGI:MGI:1925309 +78060 4930593C16Rik MGI:MGI:1925310|Ensembl:ENSMUSG00000086365 +78062 4930595D18Rik MGI:MGI:1925312|Ensembl:ENSMUSG00000083193|Vega:OTTMUSG00000031734 +78067 5830426I08Rik MGI:MGI:1925317 +78068 6430503K07Rik MGI:MGI:1925318|Ensembl:ENSMUSG00000053545 +78070 Cpt1c MGI:MGI:2446526|Ensembl:ENSMUSG00000007783|Vega:OTTMUSG00000058336 +78071 5330429C05Rik MGI:MGI:1925321 +78072 5930435M05Rik MGI:MGI:1925322 +78073 6720468P15Rik MGI:MGI:1925323 +78074 6720484C15Rik MGI:MGI:1925324 +78076 Lcn8 MGI:MGI:2135945|Ensembl:ENSMUSG00000036449|Vega:OTTMUSG00000012516 +78078 9230108I15Rik MGI:MGI:1925328 +78079 9130219B18Rik MGI:MGI:1925329 +78080 9230114J08Rik MGI:MGI:1925330 +78081 Crisp4 MGI:MGI:1925331|Ensembl:ENSMUSG00000025774|Vega:OTTMUSG00000022295 +78082 9230117E06Rik MGI:MGI:1925332|Ensembl:ENSMUSG00000089874 +78085 4930471C06Rik MGI:MGI:1925335 +78086 4930555B12Rik MGI:MGI:1925336|Ensembl:ENSMUSG00000085619 +78087 5730402E23Rik MGI:MGI:1925337 +78088 Sowahb MGI:MGI:1925338|Ensembl:ENSMUSG00000045314|Vega:OTTMUSG00000055616 +78091 4921501I09Rik MGI:MGI:1925341 +78092 Samt1 MGI:MGI:3709338|Ensembl:ENSMUSG00000094802|Vega:OTTMUSG00000019268 +78095 5430434F05Rik MGI:MGI:1925345 +78100 Msantd4 MGI:MGI:1925350|Ensembl:ENSMUSG00000041124|Vega:OTTMUSG00000061685 +78101 8430411E10Rik MGI:MGI:1925351 +78102 8430426J06Rik MGI:MGI:1925352 +78103 8430431K14Rik MGI:MGI:1925353 +78104 4833413E03Rik MGI:MGI:1925354 +78105 Grip1os1 MGI:MGI:1922226|Ensembl:ENSMUSG00000085418 +78106 4930405L22Rik MGI:MGI:1925356|Ensembl:ENSMUSG00000106602 +78107 4930425F17Rik MGI:MGI:1925357 +78108 Particl MGI:MGI:1925358|Ensembl:ENSMUSG00000108591 +78109 Lrp8os1 MGI:MGI:1925359 +78110 4930428D20Rik MGI:MGI:1925360|Ensembl:ENSMUSG00000107073 +78111 4930451E10Rik MGI:MGI:1925361 +78112 4930452N14Rik MGI:MGI:1925362|Ensembl:ENSMUSG00000099933 +78114 4930434O05Rik MGI:MGI:1925364 +78115 4930445E18Rik MGI:MGI:1925365 +78116 4930435F05Rik MGI:MGI:1925366 +78117 4930447E19Rik MGI:MGI:1925367 +78118 4930451I11Rik MGI:MGI:1925368|Ensembl:ENSMUSG00000045989|Vega:OTTMUSG00000058358 +78119 4930439A04Rik MGI:MGI:1925369 +78120 4930449E18Rik MGI:MGI:1925370 +78122 4930445N08Rik MGI:MGI:1925372 +78123 4930448L02Rik MGI:MGI:1925373 +78124 Spata31 MGI:MGI:1925374|Ensembl:ENSMUSG00000056223|Vega:OTTMUSG00000043224 +78126 1700001J04Rik MGI:MGI:1919075 +78127 4930525C09Rik MGI:MGI:1925377|Ensembl:ENSMUSG00000112497 +78128 Spag11a MGI:MGI:1925378|Ensembl:ENSMUSG00000079842|Vega:OTTMUSG00000020599 +78131 4930433E05Rik MGI:MGI:1925381 +78132 4930440F04Rik MGI:MGI:1925382 +78134 Lpar4 MGI:MGI:1925384|Ensembl:ENSMUSG00000049929|Vega:OTTMUSG00000018372 +78135 4921501M06Rik MGI:MGI:1925385 +78136 4922502H24Rik MGI:MGI:1925386 +78137 4921540A03Rik MGI:MGI:1925387 +78139 4933439N14Rik MGI:MGI:1925389 +78141 5430409L15Rik MGI:MGI:1925391 +78145 7330404K18Rik MGI:MGI:1925395 +78146 7330423F06Rik MGI:MGI:1925396 +78147 8430439B09Rik MGI:MGI:1925397 +78148 8430430B14Rik MGI:MGI:1925398 +78150 4930405E02Rik MGI:MGI:1925400 +78151 4930404H24Rik MGI:MGI:1925401 +78154 4930430O22Rik MGI:MGI:1925404 +78156 4930441H08Rik MGI:MGI:1925406|Ensembl:ENSMUSG00000108669 +78158 4930440I19Rik MGI:MGI:1925408|Ensembl:ENSMUSG00000085431 +78160 4930442G15Rik MGI:MGI:1925410 +78162 4930435C17Rik MGI:MGI:1925412 +78163 4930459L07Rik MGI:MGI:1925413|Ensembl:ENSMUSG00000105234 +78164 4930441N18Rik MGI:MGI:1925414 +78165 4930445N06Rik MGI:MGI:1925415 +78167 4930439D14Rik MGI:MGI:1925417 +78168 4930477G07Rik MGI:MGI:1925418 +78169 4930483P17Rik MGI:MGI:1925419 +78170 4930486F22Rik MGI:MGI:1925420|Ensembl:ENSMUSG00000112493 +78171 4930479H17Rik MGI:MGI:1925421 +78172 4930487D11Rik MGI:MGI:1925422|Ensembl:ENSMUSG00000106932 +78174 Cox7b2 MGI:MGI:1925424|Ensembl:ENSMUSG00000049387|Vega:OTTMUSG00000054260 +78176 4930471C04Rik MGI:MGI:1925426|Ensembl:ENSMUSG00000091686 +78177 Ninl MGI:MGI:1925427|Ensembl:ENSMUSG00000068115|Vega:OTTMUSG00000015788 +78178 4930511A08Rik MGI:MGI:1925428|Ensembl:ENSMUSG00000045095 +78179 4930520K02Rik MGI:MGI:1925429 +78180 4930522O17Rik MGI:MGI:1925430|Ensembl:ENSMUSG00000086947 +78181 4930517L18Rik MGI:MGI:1925431 +78182 4930520M14Rik MGI:MGI:1925432 +78183 4930522P08Rik MGI:MGI:1925433 +78184 4930512P04Rik MGI:MGI:1925434 +78185 Flicr MGI:MGI:1925435|Ensembl:ENSMUSG00000039545 +78187 4930534D22Rik MGI:MGI:1925437 +78188 4930539H15Rik MGI:MGI:1925438 +78192 4930540I17Rik MGI:MGI:1925442 +78193 4930528P14Rik MGI:MGI:1925443|Ensembl:ENSMUSG00000087309 +78194 4930546K05Rik MGI:MGI:1925444|Ensembl:ENSMUSG00000111767 +78195 4930528J18Rik MGI:MGI:1925445 +78196 4930546J17Rik MGI:MGI:1925446 +78197 4930544I03Rik MGI:MGI:1925447 +78198 4930527E20Rik MGI:MGI:1925448 +78199 4930527G23Rik MGI:MGI:1925449 +78200 4930538E20Rik MGI:MGI:1925450|Ensembl:ENSMUSG00000085516 +78201 4930546O09Rik MGI:MGI:1925451 +78202 4930557K07Rik MGI:MGI:1925452|Ensembl:ENSMUSG00000108034 +78203 4930551E15Rik MGI:MGI:1925453 +78204 4930563A19Rik MGI:MGI:1925454 +78206 4930552P06Rik MGI:MGI:1925456 +78207 4930556G22Rik MGI:MGI:1925457 +78209 4930556H05Rik MGI:MGI:1925459 +78210 4930549L11Rik MGI:MGI:1925460 +78211 4930558N11Rik MGI:MGI:1925461 +78212 Rbm46os MGI:MGI:1925462|Ensembl:ENSMUSG00000086273 +78213 4930563M20Rik MGI:MGI:1925463 +78214 4930589O11Rik MGI:MGI:1925464 +78215 4930578N18Rik MGI:MGI:1925465 +78216 4930584D05Rik MGI:MGI:1925466 +78217 Tmem210 MGI:MGI:1925467|Ensembl:ENSMUSG00000026963|Vega:OTTMUSG00000011905 +78218 4930573I07Rik MGI:MGI:1925468 +78219 4930568E12Rik MGI:MGI:1925469|Ensembl:ENSMUSG00000111830 +78221 4930567J20Rik MGI:MGI:1925471 +78223 4930577H14Rik MGI:MGI:1925473 +78224 4930571N24Rik MGI:MGI:1925474 +78225 4930570D08Rik MGI:MGI:1925475 +78226 4930588D02Rik MGI:MGI:1925476 +78229 4930596I21Rik MGI:MGI:1925479|Ensembl:ENSMUSG00000104900 +78230 5033405D04Rik MGI:MGI:1925480 +78232 Trappc6b MGI:MGI:1925482|Ensembl:ENSMUSG00000020993 +78233 6330522J23Rik MGI:MGI:1925483 +78235 8530402H02Rik MGI:MGI:1925485 +78236 5330417P21Rik MGI:MGI:1925486 +78237 5330439M10Rik MGI:MGI:1925487 +78238 6030471H07Rik MGI:MGI:1925488|Ensembl:ENSMUSG00000085217 +78239 Spint4 MGI:MGI:1925489|Ensembl:ENSMUSG00000017310|Vega:OTTMUSG00000001098 +78240 Cst11 MGI:MGI:1925490|Ensembl:ENSMUSG00000036958|Vega:OTTMUSG00000015725 +78242 Spink12 MGI:MGI:1925492|Ensembl:ENSMUSG00000061144|Vega:OTTMUSG00000028110 +78243 9230112D13Rik MGI:MGI:1925493|Ensembl:ENSMUSG00000021797 +78244 Dnajc21 MGI:MGI:1925371|Ensembl:ENSMUSG00000044224|Vega:OTTMUSG00000033460 +78245 Acbd7 MGI:MGI:1925495|Ensembl:ENSMUSG00000026644|Vega:OTTMUSG00000010783 +78246 Phf23 MGI:MGI:1925496|Ensembl:ENSMUSG00000018572|Vega:OTTMUSG00000006021 +78248 Armcx1 MGI:MGI:1925498|Ensembl:ENSMUSG00000033460|Vega:OTTMUSG00000019429 +78249 Adgrf4 MGI:MGI:1925499|Ensembl:ENSMUSG00000023918|Vega:OTTMUSG00000035525 +78250 Iqch MGI:MGI:1925500|Ensembl:ENSMUSG00000037801|Vega:OTTMUSG00000036544 +78251 Zfp712 MGI:MGI:1925501|Ensembl:ENSMUSG00000090641 +78252 Nxpe2 MGI:MGI:1925502|Ensembl:ENSMUSG00000032028|Vega:OTTMUSG00000027436 +78254 Zfp286it MGI:MGI:1925504 +78255 Ralgps2 MGI:MGI:1925505|Ensembl:ENSMUSG00000026594|Vega:OTTMUSG00000049722 +78256 4921539H07Rik MGI:MGI:1925506 +78257 Lrrc9 MGI:MGI:1925507|Ensembl:ENSMUSG00000021090|Vega:OTTMUSG00000034236 +78258 Mroh9 MGI:MGI:1925508|Ensembl:ENSMUSG00000071890|Vega:OTTMUSG00000050999 +78263 4632411P08Rik MGI:MGI:1925513 +78265 4632418H02Rik MGI:MGI:1925515 +78266 Zfp687 MGI:MGI:1925516|Ensembl:ENSMUSG00000019338|Vega:OTTMUSG00000019659 +78267 Klhdc8b MGI:MGI:1925517|Ensembl:ENSMUSG00000032609|Vega:OTTMUSG00000050757 +78268 5330423I11Rik MGI:MGI:1925518 +78271 5330427O13Rik MGI:MGI:1925521 +78274 5330430C04Rik MGI:MGI:1925524 +78276 5330433J24Rik MGI:MGI:1925526 +78277 5330428N10Rik MGI:MGI:1925527 +78279 5330421C15Rik MGI:MGI:1925529 +78280 5330430B06Rik MGI:MGI:1925530 +78282 5330439K02Rik MGI:MGI:1925532 +78283 Map7d2 MGI:MGI:1917474|Ensembl:ENSMUSG00000041020|Vega:OTTMUSG00000019440 +78284 Creb3l4 MGI:MGI:1916603|Ensembl:ENSMUSG00000027938|Vega:OTTMUSG00000021959 +78285 5330426L24Rik MGI:MGI:1925535 +78286 Nav2 MGI:MGI:2183691|Ensembl:ENSMUSG00000052512|Vega:OTTMUSG00000043214 +78287 Rbsn MGI:MGI:1925537|Ensembl:ENSMUSG00000014550|Vega:OTTMUSG00000023797 +78288 5330421F21Rik MGI:MGI:1925538 +78294 Rps27a MGI:MGI:1925544|Ensembl:ENSMUSG00000020460|Vega:OTTMUSG00000005330 +78297 0610008J02Rik MGI:MGI:1925547 +78298 0610012E21Rik MGI:MGI:1925548 +78299 0610031C06Rik MGI:MGI:1925549 +78301 0610033I19Rik MGI:MGI:1925551 +78303 Hist3h2ba MGI:MGI:1925553|Ensembl:ENSMUSG00000056895|Vega:OTTMUSG00000005770 +78304 Naa38 MGI:MGI:1925554|Ensembl:ENSMUSG00000059278|Vega:OTTMUSG00000005977 +78305 1500032F14Rik MGI:MGI:1925555 +78306 Tsga10ip MGI:MGI:1925556 +78308 Gpr108 MGI:MGI:1925558|Ensembl:ENSMUSG00000005823 +78309 Cul9 MGI:MGI:1925559|Ensembl:ENSMUSG00000040327|Vega:OTTMUSG00000043230 +78312 1810041H14Rik MGI:MGI:1925562|Ensembl:ENSMUSG00000102112 +78313 2410006F04Rik MGI:MGI:1925563 +78316 Platr27 MGI:MGI:1925566|Ensembl:ENSMUSG00000087547 +78317 Ccdc88b MGI:MGI:1925567|Ensembl:ENSMUSG00000047810 +78319 2700001H16Rik MGI:MGI:1925569 +78321 Ankrd23 MGI:MGI:1925571|Ensembl:ENSMUSG00000067653|Vega:OTTMUSG00000049836 +78323 Fam219b MGI:MGI:1925573|Ensembl:ENSMUSG00000032305|Vega:OTTMUSG00000063189 +78324 2900002M20Rik MGI:MGI:1925574 +78326 2700078K13Rik MGI:MGI:1925576 +78328 1810035K13Rik MGI:MGI:1925578 +78329 2310010J17Rik MGI:MGI:1925579|Ensembl:ENSMUSG00000097162 +78330 Ndufv3 MGI:MGI:1890894|Ensembl:ENSMUSG00000024038|Vega:OTTMUSG00000047655 +78332 2510010K19Rik MGI:MGI:1925582 +78334 Cdk19 MGI:MGI:1925584|Ensembl:ENSMUSG00000038481|Vega:OTTMUSG00000063431 +78335 2810030D12Rik MGI:MGI:1925585 +78338 2900037P16Rik MGI:MGI:1925588 +78339 Ttyh3 MGI:MGI:1925589|Ensembl:ENSMUSG00000036565|Vega:OTTMUSG00000054833 +78341 2900016J10Rik MGI:MGI:1925591 +78343 3110004A20Rik MGI:MGI:1925593|Ensembl:ENSMUSG00000085588 +78348 1700043A12Rik MGI:MGI:1925598 +78349 1700034K08Rik MGI:MGI:1925599|Ensembl:ENSMUSG00000100294 +78350 1700054K02Rik MGI:MGI:1925600 +78353 2500002B13Rik MGI:MGI:1925603|Ensembl:ENSMUSG00000096917 +78354 2210407C18Rik MGI:MGI:1925604|Ensembl:ENSMUSG00000037145|Vega:OTTMUSG00000005752 +78363 0610033P13Rik MGI:MGI:1925613 +78364 0610037L18Rik MGI:MGI:1925614 +78365 Lhx1os MGI:MGI:1925615|Ensembl:ENSMUSG00000087211 +78369 Icam4 MGI:MGI:1925619|Ensembl:ENSMUSG00000001014|Vega:OTTMUSG00000063056 +78372 Snrnp25 MGI:MGI:1925622|Ensembl:ENSMUSG00000040767|Vega:OTTMUSG00000005369 +78373 Nudt17 MGI:MGI:1925623|Ensembl:ENSMUSG00000028100|Vega:OTTMUSG00000053149 +78375 2810433H14Rik MGI:MGI:1925625 +78376 Sapcd1 MGI:MGI:2388100|Ensembl:ENSMUSG00000036185|Vega:OTTMUSG00000037143 +78377 1700016D08Rik MGI:MGI:1925627 +78378 1700006P03Rik MGI:MGI:1925628 +78380 2600002D14Rik MGI:MGI:1925630 +78381 2310047N11Rik MGI:MGI:1925631 +78382 Lce6a MGI:MGI:1925632|Ensembl:ENSMUSG00000086848|Vega:OTTMUSG00000034069 +78384 2210420L05Rik MGI:MGI:1925634 +78385 2310063J23Rik MGI:MGI:1925635 +78388 Mvp MGI:MGI:1925638|Ensembl:ENSMUSG00000030681|Vega:OTTMUSG00000025144 +78390 Pla2g4d MGI:MGI:1925640|Ensembl:ENSMUSG00000070719|Vega:OTTMUSG00000015285 +78391 2610524J22Rik MGI:MGI:1925641 +78393 2610318M16Rik MGI:MGI:1925643 +78394 Ddx52 MGI:MGI:1925644|Ensembl:ENSMUSG00000020677|Vega:OTTMUSG00000000973 +78396 2810028B13Rik MGI:MGI:1925646 +78398 2900002H24Rik MGI:MGI:1925648 +78401 2900042G08Rik MGI:MGI:1925651 +78402 2900037B21Rik MGI:MGI:1925652 +78403 2900041M22Rik MGI:MGI:1925653 +78405 Ntf5 MGI:MGI:97381|Ensembl:ENSMUSG00000074121|Vega:OTTMUSG00000059407 +78406 2900041H08Rik MGI:MGI:1925656 +78408 Fam131a MGI:MGI:1925658|Ensembl:ENSMUSG00000050821|Vega:OTTMUSG00000028509 +78409 2900079J23Rik MGI:MGI:1925659 +78410 2900083M14Rik MGI:MGI:1925660 +78411 3110033O22Rik MGI:MGI:1925661 +78412 3110062M04Rik MGI:MGI:1925662|Ensembl:ENSMUSG00000046806|Vega:OTTMUSG00000022823 +78414 1700034E13Rik MGI:MGI:1925664|Ensembl:ENSMUSG00000024532|Vega:OTTMUSG00000028206 +78415 1700052M18Rik MGI:MGI:1925665 +78416 Rnase6 MGI:MGI:1925666|Ensembl:ENSMUSG00000021880 +78417 9530034D02Rik MGI:MGI:1925667 +78419 9530047P18Rik MGI:MGI:1925669 +78420 Bcas3os2 MGI:MGI:1925670|Ensembl:ENSMUSG00000085514 +78421 9530046B11Rik MGI:MGI:1925671 +78422 9530039L23Rik MGI:MGI:1925672 +78423 9530049O05Rik MGI:MGI:1925673 +78424 9530032E18Rik MGI:MGI:1925674 +78425 9530053H05Rik MGI:MGI:1925675 +78428 Pym1 MGI:MGI:1925678|Ensembl:ENSMUSG00000064030 +78434 A930009K04Rik MGI:MGI:1925684 +78435 A930014E10Rik MGI:MGI:1925685 +78436 A930018C05Rik MGI:MGI:1925686 +78438 A930028N01Rik MGI:MGI:1925688 +78439 A930037H05Rik MGI:MGI:1925689 +78441 A930033M14Rik MGI:MGI:1925691 +78443 A930041C12Rik MGI:MGI:1925693|Ensembl:ENSMUSG00000085900 +78444 Pgpep1l MGI:MGI:1925694|Ensembl:ENSMUSG00000030553|Vega:OTTMUSG00000059610 +78445 C330013E15Rik MGI:MGI:1925695|Ensembl:ENSMUSG00000097093 +78446 D730050B12Rik MGI:MGI:1925696|Ensembl:ENSMUSG00000113082 +78448 D730044P03Rik MGI:MGI:1925698 +78449 2700046A07Rik MGI:MGI:1919803|Ensembl:ENSMUSG00000041789 +78451 4930407I02Rik MGI:MGI:1925701 +78452 9530075M24Rik MGI:MGI:1925702 +78454 9530077C14Rik MGI:MGI:1925704 +78455 Helz MGI:MGI:1925705|Ensembl:ENSMUSG00000020721|Vega:OTTMUSG00000003095 +78456 C030002A05Rik MGI:MGI:1925706 +78457 1700054A03Rik MGI:MGI:1925707|Ensembl:ENSMUSG00000099988 +78458 1700064N11Rik MGI:MGI:1925708 +78459 1700057G04Rik MGI:MGI:1925709|Ensembl:ENSMUSG00000074139|Vega:OTTMUSG00000022736 +78460 1700057H15Rik MGI:MGI:1925710 +78461 1700062A02Rik MGI:MGI:1925711 +78462 1700065I16Rik MGI:MGI:1925712|Ensembl:ENSMUSG00000099435 +78463 1700065F09Rik MGI:MGI:1925713 +78465 Ccdc190 MGI:MGI:1925715|Ensembl:ENSMUSG00000070532|Vega:OTTMUSG00000026878 +78467 1700087M22Rik MGI:MGI:1925717|Ensembl:ENSMUSG00000087653 +78469 Tmem247 MGI:MGI:1925719|Ensembl:ENSMUSG00000037689|Vega:OTTMUSG00000056172 +78470 1700112H04Rik MGI:MGI:1925720 +78471 1700109G15Rik MGI:MGI:1925721|Ensembl:ENSMUSG00000085044 +78473 Skap1 MGI:MGI:1925723|Ensembl:ENSMUSG00000057058|Vega:OTTMUSG00000001774 +78477 1700121M21Rik MGI:MGI:1925727 +78478 Tmsb15a MGI:MGI:1925728|Ensembl:ENSMUSG00000060726|Vega:OTTMUSG00000018773 +78479 1700119I11Rik MGI:MGI:1925729 +78481 1700123J03Rik MGI:MGI:1925731 +78482 1700123L14Rik MGI:MGI:1925732|Ensembl:ENSMUSG00000072878|Vega:OTTMUSG00000029711 +78485 2200007N16Rik MGI:MGI:1925735 +78486 2210414L08Rik MGI:MGI:1925736 +78488 1810056I18Rik MGI:MGI:1925738 +78491 Tspan2os MGI:MGI:1925741|Ensembl:ENSMUSG00000086745 +78496 1700015O03Rik MGI:MGI:1925746 +78498 1810073J14Rik MGI:MGI:1925748 +78499 1700109O10Rik MGI:MGI:1925749 +78500 1700063D05Rik MGI:MGI:1925750|Ensembl:ENSMUSG00000100837 +78506 Micu3 MGI:MGI:1925756|Ensembl:ENSMUSG00000039478|Vega:OTTMUSG00000031719 +78508 Frmpd1os MGI:MGI:1925758|Ensembl:ENSMUSG00000086284 +78512 3300005D01Rik MGI:MGI:1925762|Ensembl:ENSMUSG00000096965 +78514 Arhgap10 MGI:MGI:1925764|Ensembl:ENSMUSG00000037148|Vega:OTTMUSG00000061241 +78518 2900009I19Rik MGI:MGI:1925768 +78520 C330022C24Rik MGI:MGI:1925770|Ensembl:ENSMUSG00000099590 +78521 B230219D22Rik MGI:MGI:1925771|Ensembl:ENSMUSG00000045767 +78523 Mrpl9 MGI:MGI:2137211|Ensembl:ENSMUSG00000028140|Vega:OTTMUSG00000022464 +78524 C330016L05Rik MGI:MGI:1925774 +78525 C330024E10Rik MGI:MGI:1925775 +78526 Platr21 MGI:MGI:1925776|Ensembl:ENSMUSG00000086807 +78527 C330019O22Rik MGI:MGI:1925777 +78531 C330026N13Rik MGI:MGI:1925781 +78532 C030006F08Rik MGI:MGI:1925782 +78534 C430005N20Rik MGI:MGI:1925784 +78535 C430004N12Rik MGI:MGI:1925785 +78536 C030004G16Rik MGI:MGI:1925786 +78537 C030005H24Rik MGI:MGI:1925787 +78541 Asb8 MGI:MGI:1925791|Ensembl:ENSMUSG00000048175|Vega:OTTMUSG00000032735 +78544 C030001C17Rik MGI:MGI:1925794 +78545 C430014O12Rik MGI:MGI:1925795 +78547 E130304I02Rik MGI:MGI:1925797|Ensembl:ENSMUSG00000044997 +78550 E130119H09Rik MGI:MGI:1925800 +78551 5430407F15Rik MGI:MGI:1925801 +78552 E130201H02Rik MGI:MGI:1925802|Ensembl:ENSMUSG00000044141 +78553 E130118H10Rik MGI:MGI:1925803 +78557 9530071P10Rik MGI:MGI:1925807 +78558 Htra3 MGI:MGI:1925808|Ensembl:ENSMUSG00000029096|Vega:OTTMUSG00000024097 +78560 Adgra2 MGI:MGI:1925810|Ensembl:ENSMUSG00000031486|Vega:OTTMUSG00000042301 +78564 9530078K11Rik MGI:MGI:1925814 +78566 9530085P06Rik MGI:MGI:1925816 +78567 9630003H22Rik MGI:MGI:1925817 +78568 9630009A06Rik MGI:MGI:1925818 +78569 9630015K15Rik MGI:MGI:1925819 +78570 9630014C11Rik MGI:MGI:1925820 +78571 C630050I24Rik MGI:MGI:1925821 +78572 D730004N08Rik MGI:MGI:1925822 +78573 D530037P16Rik MGI:MGI:1925823 +78574 D530033B14Rik MGI:MGI:1925824 +78575 B430319G15Rik MGI:MGI:3603454|Ensembl:ENSMUSG00000103622 +78576 D730001M18Rik MGI:MGI:1925826 +78579 D530043N20Rik MGI:MGI:1925829 +78580 D730003K21Rik MGI:MGI:1925830 +78581 Utp23 MGI:MGI:1925831|Ensembl:ENSMUSG00000022313|Vega:OTTMUSG00000032780 +78584 D530039A21Rik MGI:MGI:1925834 +78586 Srbd1 MGI:MGI:1925836|Ensembl:ENSMUSG00000024135 +78589 Gm9802 MGI:MGI:3704390 +78591 Mir142hg MGI:MGI:1925841 +78592 A330106M24Rik MGI:MGI:1925842 +78593 Nrip3 MGI:MGI:1925843|Ensembl:ENSMUSG00000034825|Vega:OTTMUSG00000027286 +78594 A430109H19Rik MGI:MGI:1925844 +78597 Gm9955 MGI:MGI:3642397 +78598 A930014E01Rik MGI:MGI:1925848 +78599 A930030B21Rik MGI:MGI:1925849 +78600 Pde6h MGI:MGI:1925850|Ensembl:ENSMUSG00000064330|Vega:OTTMUSG00000023391 +78603 B230216N24Rik MGI:MGI:1925853|Ensembl:ENSMUSG00000089706 +78604 B430006N09Rik MGI:MGI:1925854 +78605 6430706D22Rik MGI:MGI:1925855 +78607 E130102B10Rik MGI:MGI:1925857 +78609 8030411F24Rik MGI:MGI:1925859|Ensembl:ENSMUSG00000027444|Vega:OTTMUSG00000015726 +78610 Uvrag MGI:MGI:1925860|Ensembl:ENSMUSG00000035354|Vega:OTTMUSG00000058912 +78611 Btbd19 MGI:MGI:1925861 +78612 9530034A14Rik MGI:MGI:1925862 +78614 9530041E20Rik MGI:MGI:1925864 +78615 9530034E10Rik MGI:MGI:1925865 +78616 9530036M11Rik MGI:MGI:1925866 +78617 Cstad MGI:MGI:1925867|Ensembl:ENSMUSG00000047363|Vega:OTTMUSG00000016803 +78618 Acap2 MGI:MGI:1925868|Ensembl:ENSMUSG00000049076 +78619 Zfp449 MGI:MGI:1925869|Ensembl:ENSMUSG00000073176|Vega:OTTMUSG00000017518 +78623 1700041B01Rik MGI:MGI:1925873 +78624 1700048G13Rik MGI:MGI:1925874 +78625 1700061G19Rik MGI:MGI:1925875|Ensembl:ENSMUSG00000024209|Vega:OTTMUSG00000031269 +78627 1700063I16Rik MGI:MGI:1925877 +78628 1700074G04Rik MGI:MGI:1925878 +78629 1700072I22Rik MGI:MGI:1925879 +78630 1700089I07Rik MGI:MGI:1925880 +78631 Cypt15 MGI:MGI:3616461|Ensembl:ENSMUSG00000079619|Vega:OTTMUSG00000017228 +78632 1700080C20Rik MGI:MGI:1925882 +78633 1700096C16Rik MGI:MGI:1925883 +78634 Spaca7 MGI:MGI:1925884|Ensembl:ENSMUSG00000010435|Vega:OTTMUSG00000060862 +78635 Kcnd3os MGI:MGI:1925885|Ensembl:ENSMUSG00000074346 +78638 1700113B09Rik MGI:MGI:1925888|Ensembl:ENSMUSG00000112028 +78639 1700116B05Rik MGI:MGI:1925889|Ensembl:ENSMUSG00000092276 +78640 1700122C19Rik MGI:MGI:1925890 +78641 1700121C08Rik MGI:MGI:1925891 +78642 1700127F24Rik MGI:MGI:1925892 +78643 1700129O19Rik MGI:MGI:1925893 +78648 2400006E01Rik MGI:MGI:1925898 +78650 Platr5 MGI:MGI:1925900|Ensembl:ENSMUSG00000097398 +78651 Lsm6 MGI:MGI:1925901|Ensembl:ENSMUSG00000031683|Vega:OTTMUSG00000032840 +78653 Bola3 MGI:MGI:1925903|Ensembl:ENSMUSG00000045160|Vega:OTTMUSG00000027009 +78654 1700066C05Rik MGI:MGI:1925904 +78655 Eif3j1 MGI:MGI:1925905|Ensembl:ENSMUSG00000027236|Vega:OTTMUSG00000015531 +78656 Brd8 MGI:MGI:1925906|Ensembl:ENSMUSG00000003778|Vega:OTTMUSG00000017276 +78657 2900034K13Rik MGI:MGI:1925907 +78658 Ncapd3 MGI:MGI:2142989|Ensembl:ENSMUSG00000035024|Vega:OTTMUSG00000062730 +78666 9530067L11Rik MGI:MGI:1925916 +78667 9530062E16Rik MGI:MGI:1925917 +78668 E130112N10Rik MGI:MGI:1925933|Ensembl:ENSMUSG00000030337 +78670 Plekhj1 MGI:MGI:1925920|Ensembl:ENSMUSG00000035278 +78672 9530057J20Rik MGI:MGI:1925922 +78685 B430105A11Rik MGI:MGI:1925935 +78687 0610025J13Rik MGI:MGI:1915618 +78688 Nol3 MGI:MGI:1925938|Ensembl:ENSMUSG00000014776|Vega:OTTMUSG00000062040 +78689 Naa35 MGI:MGI:1925939|Ensembl:ENSMUSG00000021555|Vega:OTTMUSG00000035355 +78690 C030006N10Rik MGI:MGI:1925940 +78692 B830042I05Rik MGI:MGI:1925942 +78693 C030004M13Rik MGI:MGI:1925943 +78695 C030005K06Rik MGI:MGI:1925945 +78697 Pus7 MGI:MGI:1925947|Ensembl:ENSMUSG00000057541|Vega:OTTMUSG00000028491 +78698 C330025O08Rik MGI:MGI:1925948 +78699 C330022B21Rik MGI:MGI:1925949 +78703 Zfp972 MGI:MGI:1925953|Ensembl:ENSMUSG00000074529|Vega:OTTMUSG00000016604 +78706 Platr4 MGI:MGI:1925956|Ensembl:ENSMUSG00000097639 +78709 Spink8 MGI:MGI:1925959|Ensembl:ENSMUSG00000050074|Vega:OTTMUSG00000027486 +78711 C630043D15Rik MGI:MGI:1925961 +78712 C630044B11Rik MGI:MGI:1925962 +78713 D530017H19Rik MGI:MGI:1925963 +78715 D530015H24Rik MGI:MGI:1925965 +78717 D530014G21Rik MGI:MGI:1925967 +78718 D530049I02Rik MGI:MGI:1925968|Ensembl:ENSMUSG00000101812 +78719 D530034E23Rik MGI:MGI:1925969 +78720 D530035G10Rik MGI:MGI:1925970 +78723 Pramef12os MGI:MGI:1925973 +78724 D530031A16Rik MGI:MGI:1925974 +78725 D730001G18Rik MGI:MGI:1925975|Ensembl:ENSMUSG00000101026|Vega:OTTMUSG00000045149 +78730 E130114A11Rik MGI:MGI:1925980 +78732 E130303B20Rik MGI:MGI:1925982 +78733 Troap MGI:MGI:1925983|Ensembl:ENSMUSG00000032783 +78734 8030402F09Rik MGI:MGI:1925984 +78737 9530053I22Rik MGI:MGI:1925987 +78739 9530062K07Rik MGI:MGI:1925989|Ensembl:ENSMUSG00000108030 +78741 9530086O07Rik MGI:MGI:1925991 +78742 9530086P17Rik MGI:MGI:1925992 +78743 9630005C17Rik MGI:MGI:1925993 +78744 9630009N12Rik MGI:MGI:1925994 +78745 9530097N15Rik MGI:MGI:1925995 +78748 Rassf10 MGI:MGI:1925998|Ensembl:ENSMUSG00000098132|Vega:OTTMUSG00000043540 +78749 Filip1l MGI:MGI:1925999|Ensembl:ENSMUSG00000043336|Vega:OTTMUSG00000034217 +78751 Zc3h6 MGI:MGI:1926001|Ensembl:ENSMUSG00000042851|Vega:OTTMUSG00000015414 +78752 Csgalnact2 MGI:MGI:1926002|Ensembl:ENSMUSG00000042042|Vega:OTTMUSG00000022841 +78753 Lipm MGI:MGI:1926003|Ensembl:ENSMUSG00000056078 +78754 Galnt15 MGI:MGI:1926004|Ensembl:ENSMUSG00000021903|Vega:OTTMUSG00000035518 +78755 Fam122b MGI:MGI:1926005|Ensembl:ENSMUSG00000036022|Vega:OTTMUSG00000017350 +78757 Rictor MGI:MGI:1926007|Ensembl:ENSMUSG00000050310 +78758 4921518K17Rik MGI:MGI:1926008|Ensembl:ENSMUSG00000085851 +78762 4933424L21Rik MGI:MGI:1926012 +78767 Efcab11 MGI:MGI:1926017|Ensembl:ENSMUSG00000021176 +78771 Mctp1 MGI:MGI:1926021|Ensembl:ENSMUSG00000021596|Vega:OTTMUSG00000025745 +78772 Hhipl2 MGI:MGI:1926022|Ensembl:ENSMUSG00000053461|Vega:OTTMUSG00000050575 +78773 4930511E03Rik MGI:MGI:1926023|Ensembl:ENSMUSG00000108187 +78774 Cfap61 MGI:MGI:1926024|Ensembl:ENSMUSG00000037143|Vega:OTTMUSG00000004123 +78777 Tepsin MGI:MGI:1926027|Ensembl:ENSMUSG00000025377|Vega:OTTMUSG00000004100 +78779 Spata2l MGI:MGI:1926029|Ensembl:ENSMUSG00000033594|Vega:OTTMUSG00000061958 +78781 Zc3hav1 MGI:MGI:1926031|Ensembl:ENSMUSG00000029826|Vega:OTTMUSG00000023645 +78783 Brpf1 MGI:MGI:1926033|Ensembl:ENSMUSG00000001632|Vega:OTTMUSG00000022740 +78784 Celf3 MGI:MGI:1926034|Ensembl:ENSMUSG00000028137|Vega:OTTMUSG00000052184 +78785 Clip4 MGI:MGI:1919100|Ensembl:ENSMUSG00000024059 +78786 4833439F03Rik MGI:MGI:1926036 +78787 Usp54 MGI:MGI:1926037|Ensembl:ENSMUSG00000034235|Vega:OTTMUSG00000025216 +78788 4930421C12Rik MGI:MGI:1926038 +78789 Vsig1 MGI:MGI:1926039|Ensembl:ENSMUSG00000031430|Vega:OTTMUSG00000018913 +78790 4930414F18Rik MGI:MGI:1926040 +78792 4930432F04Rik MGI:MGI:1926042 +78794 4930402H05Rik MGI:MGI:1926044 +78795 Armc9 MGI:MGI:1926045|Ensembl:ENSMUSG00000062590|Vega:OTTMUSG00000033936 +78796 Zcchc4 MGI:MGI:1926046|Ensembl:ENSMUSG00000029179|Vega:OTTMUSG00000023333 +78797 Ndor1 MGI:MGI:1926047|Ensembl:ENSMUSG00000006471|Vega:OTTMUSG00000011887 +78798 Eml4 MGI:MGI:1926048|Ensembl:ENSMUSG00000032624 +78800 4930480K15Rik MGI:MGI:1926050|Ensembl:ENSMUSG00000090160 +78801 Ak7 MGI:MGI:1926051|Ensembl:ENSMUSG00000041323 +78802 Ttc30a1 MGI:MGI:1926052|Ensembl:ENSMUSG00000075271|Vega:OTTMUSG00000015169 +78803 Fbxo43 MGI:MGI:1926053|Ensembl:ENSMUSG00000048230 +78805 4930545L23Rik MGI:MGI:1926055|Ensembl:ENSMUSG00000085247 +78806 Stpg1 MGI:MGI:1926056|Ensembl:ENSMUSG00000028801|Vega:OTTMUSG00000009734 +78807 4930544L04Rik MGI:MGI:1926057 +78808 Stxbp5 MGI:MGI:1926058|Ensembl:ENSMUSG00000019790|Vega:OTTMUSG00000033369 +78809 4930562C15Rik MGI:MGI:1926059|Ensembl:ENSMUSG00000022518 +78812 4930570E03Rik MGI:MGI:1926062 +78816 Gmip MGI:MGI:1926066|Ensembl:ENSMUSG00000036246|Vega:OTTMUSG00000027254 +78817 4930588G05Rik MGI:MGI:1926067 +78818 5830407P18Rik MGI:MGI:1926068 +78825 Desi2 MGI:MGI:1926075|Ensembl:ENSMUSG00000026502|Vega:OTTMUSG00000029657 +78826 P2ry10 MGI:MGI:1926076|Ensembl:ENSMUSG00000050921|Vega:OTTMUSG00000018160 +78827 5830426C09Rik MGI:MGI:1926077 +78829 Tsc22d4 MGI:MGI:1926079|Ensembl:ENSMUSG00000029723|Vega:OTTMUSG00000022818 +78830 Slc25a12 MGI:MGI:1926080|Ensembl:ENSMUSG00000027010|Vega:OTTMUSG00000013185 +78832 Cacul1 MGI:MGI:1926082|Ensembl:ENSMUSG00000033417 +78833 Gins3 MGI:MGI:1926083|Ensembl:ENSMUSG00000031669|Vega:OTTMUSG00000061775 +78834 Zfp623 MGI:MGI:1926084|Ensembl:ENSMUSG00000050846 +78843 B230207M22Rik MGI:MGI:1926093 +78844 B230206I08Rik MGI:MGI:1926094 +78848 B230219J02Rik MGI:MGI:1926098 +78849 B430010I23Rik MGI:MGI:1926099|Ensembl:ENSMUSG00000084960 +78850 9530078B04Rik MGI:MGI:1926100 +78871 B230117O15Rik MGI:MGI:1926121 +78873 B230207N12Rik MGI:MGI:1926123 +78874 B230201I24Rik MGI:MGI:1926124 +78875 B230206L23Rik MGI:MGI:1926125 +78876 B230214N19Rik MGI:MGI:1926126 +78878 Ftx MGI:MGI:1926128|Ensembl:ENSMUSG00000086370 +78881 B230219J11Rik MGI:MGI:1926131 +78882 Runx2os2 MGI:MGI:1926132 +78883 9630013K17Rik MGI:MGI:1926133|Ensembl:ENSMUSG00000086359 +78885 Coro7 MGI:MGI:1926135|Ensembl:ENSMUSG00000039637|Vega:OTTMUSG00000024696 +78887 Sfi1 MGI:MGI:1926137|Ensembl:ENSMUSG00000023764|Vega:OTTMUSG00000005013 +78889 Wsb1 MGI:MGI:1926139|Ensembl:ENSMUSG00000017677|Vega:OTTMUSG00000000167 +78890 Trmt44 MGI:MGI:1926140|Ensembl:ENSMUSG00000029097|Vega:OTTMUSG00000028672 +78891 Scyl1 MGI:MGI:1931787|Ensembl:ENSMUSG00000024941 +78892 Crispld2 MGI:MGI:1926142|Ensembl:ENSMUSG00000031825|Vega:OTTMUSG00000025222 +78893 Cnot10 MGI:MGI:1926143|Ensembl:ENSMUSG00000056167|Vega:OTTMUSG00000062855 +78894 Aacs MGI:MGI:1926144|Ensembl:ENSMUSG00000029482|Vega:OTTMUSG00000023532 +78895 Pus7l MGI:MGI:1926145|Ensembl:ENSMUSG00000033356|Vega:OTTMUSG00000023451 +78896 1500015O10Rik MGI:MGI:1926146|Ensembl:ENSMUSG00000026051|Vega:OTTMUSG00000020869 +78899 4932443L11Rik MGI:MGI:1926149 +78902 4833447P13Rik MGI:MGI:1926152 +78903 Wrnip1 MGI:MGI:1926153|Ensembl:ENSMUSG00000021400|Vega:OTTMUSG00000000693 +78906 Misp MGI:MGI:1926156|Ensembl:ENSMUSG00000035852 +78908 Igsf3 MGI:MGI:1926158|Ensembl:ENSMUSG00000042035|Vega:OTTMUSG00000052209 +78910 Asb15 MGI:MGI:1926160|Ensembl:ENSMUSG00000029685|Vega:OTTMUSG00000026855 +78911 Trim42 MGI:MGI:1926161|Ensembl:ENSMUSG00000032451|Vega:OTTMUSG00000027421 +78912 Sp2 MGI:MGI:1926162|Ensembl:ENSMUSG00000018678|Vega:OTTMUSG00000001858 +78913 Ltn1 MGI:MGI:1926163|Ensembl:ENSMUSG00000052299 +78914 Nadsyn1 MGI:MGI:1926164|Ensembl:ENSMUSG00000031090|Vega:OTTMUSG00000025932 +78916 4930425K24Rik MGI:MGI:1926166 +78917 4930455G09Rik MGI:MGI:1926167|Ensembl:ENSMUSG00000085761 +78918 4930455M05Rik MGI:MGI:1926168 +78919 Fndc8 MGI:MGI:1926169|Ensembl:ENSMUSG00000018844|Vega:OTTMUSG00000000902 +78920 Dlst MGI:MGI:1926170|Ensembl:ENSMUSG00000004789 +78921 9130019O22Rik MGI:MGI:1926171|Ensembl:ENSMUSG00000030823|Vega:OTTMUSG00000035263 +78923 Chsy3 MGI:MGI:1926173|Ensembl:ENSMUSG00000058152 +78924 4930420G21Rik MGI:MGI:1926174 +78925 Srd5a1 MGI:MGI:98400|Ensembl:ENSMUSG00000021594|Vega:OTTMUSG00000035506 +78926 Gas2l1 MGI:MGI:1926176|Ensembl:ENSMUSG00000034201|Vega:OTTMUSG00000005073 +78928 Pigt MGI:MGI:1926178|Ensembl:ENSMUSG00000017721|Vega:OTTMUSG00000001092 +78929 Polr3h MGI:MGI:1926179|Ensembl:ENSMUSG00000022476 +78931 4930546C10Rik MGI:MGI:1926181 +78933 Agbl4 MGI:MGI:1918244|Ensembl:ENSMUSG00000061298|Vega:OTTMUSG00000008502 +78934 4930581F22Rik MGI:MGI:1926184|Ensembl:ENSMUSG00000070315 +78935 Saal1 MGI:MGI:1926185|Ensembl:ENSMUSG00000006763|Vega:OTTMUSG00000023947 +78937 Avl9 MGI:MGI:1926187|Ensembl:ENSMUSG00000029787|Vega:OTTMUSG00000039874 +78938 Fbxo34 MGI:MGI:1926188|Ensembl:ENSMUSG00000037536 +78943 Ern1 MGI:MGI:1930134|Ensembl:ENSMUSG00000020715|Vega:OTTMUSG00000003414 +78944 T(4;6)77H MGI:MGI:1930112 +78945 T(4;6)77H MGI:MGI:1930113 +78977 Popdc3 MGI:MGI:1930153|Ensembl:ENSMUSG00000019848|Vega:OTTMUSG00000027973 +79043 Spsb3 MGI:MGI:1891471|Ensembl:ENSMUSG00000024160|Vega:OTTMUSG00000030430 +79044 Mrps34 MGI:MGI:1930188|Ensembl:ENSMUSG00000038880|Vega:OTTMUSG00000030475 +79045 Tce3 MGI:MGI:1930189 +79059 Nme3 MGI:MGI:1930182|Ensembl:ENSMUSG00000073435|Vega:OTTMUSG00000030474 +79189 Apc-ps1 MGI:MGI:1930261 +79195 AF313042 MGI:MGI:1930299 +79196 Osbpl5 MGI:MGI:1930265|Ensembl:ENSMUSG00000037606|Vega:OTTMUSG00000029818 +79198 Ihit1 MGI:MGI:1930302 +79199 Naip3l1 MGI:MGI:1930303 +79201 Tnfrsf23 MGI:MGI:1930269|Ensembl:ENSMUSG00000037613|Vega:OTTMUSG00000023925 +79202 Tnfrsf22 MGI:MGI:1930270|Ensembl:ENSMUSG00000010751|Vega:OTTMUSG00000032941 +79203 167L17-T7 MGI:MGI:1930529 +79204 363K16-SP6 MGI:MGI:1930538 +79205 D6Ack1 MGI:MGI:1890607 +79206 D11Bcm22 MGI:MGI:1930493 +79221 Hdac9 MGI:MGI:1931221|Ensembl:ENSMUSG00000004698|Vega:OTTMUSG00000061412 +79233 Zfp319 MGI:MGI:1890618|Ensembl:ENSMUSG00000046556|Vega:OTTMUSG00000061741 +79234 Lamr1-ps1 MGI:MGI:1930596 +79235 Lrat MGI:MGI:1891259|Ensembl:ENSMUSG00000028003|Vega:OTTMUSG00000029021 +79263 Trim39 MGI:MGI:1890659|Ensembl:ENSMUSG00000045409|Vega:OTTMUSG00000037273 +79264 Krit1 MGI:MGI:1930618|Ensembl:ENSMUSG00000000600|Vega:OTTMUSG00000053024 +79362 Bhlhe41 MGI:MGI:1930704|Ensembl:ENSMUSG00000030256|Vega:OTTMUSG00000025458 +79401 Spz1 MGI:MGI:1930801|Ensembl:ENSMUSG00000046957 +79410 Klra23 MGI:MGI:1930932 +79455 Pdcl2 MGI:MGI:1890655|Ensembl:ENSMUSG00000029235|Vega:OTTMUSG00000026468 +79456 Recql4 MGI:MGI:1931028|Ensembl:ENSMUSG00000033762 +79459 Aldoart2 MGI:MGI:1931052|Ensembl:ENSMUSG00000063129|Vega:OTTMUSG00000047064 +79464 Lias MGI:MGI:1934604|Ensembl:ENSMUSG00000029199|Vega:OTTMUSG00000028341 +79554 Cptp MGI:MGI:1933107|Ensembl:ENSMUSG00000029073|Vega:OTTMUSG00000010888 +79555 BC005537 MGI:MGI:2441726|Ensembl:ENSMUSG00000019132|Vega:OTTMUSG00000000607 +79560 Ublcp1 MGI:MGI:1933105|Ensembl:ENSMUSG00000041231|Vega:OTTMUSG00000005470 +79561 BC002245 MGI:MGI:1933144 +79565 Mettl27 MGI:MGI:1933146|Ensembl:ENSMUSG00000040557|Vega:OTTMUSG00000025980 +79566 Sh3bp5l MGI:MGI:1933124|Ensembl:ENSMUSG00000013646|Vega:OTTMUSG00000005731 +80280 Cdk5rap3 MGI:MGI:1933126|Ensembl:ENSMUSG00000018669|Vega:OTTMUSG00000001725 +80281 Cttnbp2nl MGI:MGI:1933137|Ensembl:ENSMUSG00000062127|Vega:OTTMUSG00000053155 +80283 Abtb1 MGI:MGI:1933148|Ensembl:ENSMUSG00000030083|Vega:OTTMUSG00000057475 +80284 Smim12 MGI:MGI:1933141|Ensembl:ENSMUSG00000042380|Vega:OTTMUSG00000009381 +80285 Parp9 MGI:MGI:1933117|Ensembl:ENSMUSG00000022906|Vega:OTTMUSG00000023901 +80286 Tusc3 MGI:MGI:1933134|Ensembl:ENSMUSG00000039530|Vega:OTTMUSG00000061049 +80287 Apobec3 MGI:MGI:1933111|Ensembl:ENSMUSG00000009585|Vega:OTTMUSG00000042090 +80288 Bcl9l MGI:MGI:1933114|Ensembl:ENSMUSG00000063382 +80289 Lysmd3 MGI:MGI:1915906|Ensembl:ENSMUSG00000035840 +80290 Gpr146 MGI:MGI:1933113|Ensembl:ENSMUSG00000044197|Vega:OTTMUSG00000023071 +80291 Rilpl2 MGI:MGI:1933112|Ensembl:ENSMUSG00000029401|Vega:OTTMUSG00000024444 +80292 Zxdc MGI:MGI:1933108|Ensembl:ENSMUSG00000034430|Vega:OTTMUSG00000023432 +80294 Pofut2 MGI:MGI:1916863|Ensembl:ENSMUSG00000020260 +80297 Sptbn4 MGI:MGI:1890574|Ensembl:ENSMUSG00000011751|Vega:OTTMUSG00000023763 +80334 Kcnip4 MGI:MGI:1933131|Ensembl:ENSMUSG00000029088|Vega:OTTMUSG00000042185 +80384 Tex21 MGI:MGI:1931131|Ensembl:ENSMUSG00000021056 +80385 Tusc2 MGI:MGI:1931086|Ensembl:ENSMUSG00000010054|Vega:OTTMUSG00000050781 +80509 Med8 MGI:MGI:1915269|Ensembl:ENSMUSG00000006392|Vega:OTTMUSG00000008773 +80515 Chd3os MGI:MGI:1915359|Ensembl:ENSMUSG00000043419|Vega:OTTMUSG00000059715 +80517 Herpud2 MGI:MGI:1915393|Ensembl:ENSMUSG00000008429|Vega:OTTMUSG00000062552 +80694 Del(7)Tyr-p MGI:MGI:1931116 +80695 Del(7)Tyr-p MGI:MGI:1931114 +80696 Del(7)Tyr-p MGI:MGI:1931115 +80697 Del(7)Tyr-p MGI:MGI:1931113 +80706 Olfr160 MGI:MGI:1931271|Ensembl:ENSMUSG00000061165|Vega:OTTMUSG00000061752 +80707 Wwox MGI:MGI:1931237|Ensembl:ENSMUSG00000004637|Vega:OTTMUSG00000030624 +80708 Pacsin3 MGI:MGI:1891410|Ensembl:ENSMUSG00000027257|Vega:OTTMUSG00000014429 +80718 Rab27b MGI:MGI:1931295|Ensembl:ENSMUSG00000024511|Vega:OTTMUSG00000028238 +80719 Igsf6 MGI:MGI:1891393|Ensembl:ENSMUSG00000035004|Vega:OTTMUSG00000059390 +80720 Pbx4 MGI:MGI:1931321|Ensembl:ENSMUSG00000031860|Vega:OTTMUSG00000033445 +80721 Slc19a3 MGI:MGI:1931307|Ensembl:ENSMUSG00000038496|Vega:OTTMUSG00000022622 +80732 Mynn MGI:MGI:1931415|Ensembl:ENSMUSG00000037730|Vega:OTTMUSG00000051393 +80733 Car15 MGI:MGI:1931324|Ensembl:ENSMUSG00000090236|Vega:OTTMUSG00000028899 +80743 Vps16 MGI:MGI:2136772|Ensembl:ENSMUSG00000027411|Vega:OTTMUSG00000015524 +80744 Cwc22 MGI:MGI:2136773|Ensembl:ENSMUSG00000027014|Vega:OTTMUSG00000013258 +80748 BC004004 MGI:MGI:2136782|Ensembl:ENSMUSG00000052712|Vega:OTTMUSG00000028957 +80749 Lrfn1 MGI:MGI:2136810|Ensembl:ENSMUSG00000030600|Vega:OTTMUSG00000045096 +80750 N4bp1 MGI:MGI:2136825|Ensembl:ENSMUSG00000031652|Vega:OTTMUSG00000061458 +80751 Rnf34 MGI:MGI:2153340|Ensembl:ENSMUSG00000029474|Vega:OTTMUSG00000054579 +80752 Fam20c MGI:MGI:2136853|Ensembl:ENSMUSG00000025854|Vega:OTTMUSG00000030351 +80782 Klrb1b MGI:MGI:107539|Ensembl:ENSMUSG00000079298|Ensembl:ENSMUSG00000107872|Vega:OTTMUSG00000037664|Vega:OTTMUSG00000056537 +80794 Cblc MGI:MGI:1931457|Ensembl:ENSMUSG00000040525|Vega:OTTMUSG00000029153 +80795 Selenok MGI:MGI:1931466|Ensembl:ENSMUSG00000042682|Vega:OTTMUSG00000020974 +80796 Calm4 MGI:MGI:1931464|Ensembl:ENSMUSG00000033765 +80797 Clca3a2 MGI:MGI:1931471|Ensembl:ENSMUSG00000028262|Vega:OTTMUSG00000026565 +80828 Snord82 MGI:MGI:1931502|Ensembl:ENSMUSG00000064823 +80837 Rhoj MGI:MGI:1931551|Ensembl:ENSMUSG00000046768|Vega:OTTMUSG00000027646 +80838 Hist1h1a MGI:MGI:1931523|Ensembl:ENSMUSG00000049539|Vega:OTTMUSG00000000741 +80857 Fgf20 MGI:MGI:1891346|Ensembl:ENSMUSG00000031603|Vega:OTTMUSG00000031718 +80859 Nfkbiz MGI:MGI:1931595|Ensembl:ENSMUSG00000035356|Vega:OTTMUSG00000019996 +80860 Ghdc MGI:MGI:1931556|Ensembl:ENSMUSG00000017747|Vega:OTTMUSG00000002122 +80861 Dhx58 MGI:MGI:1931560|Ensembl:ENSMUSG00000017830|Vega:OTTMUSG00000002055 +80876 Ifitm2 MGI:MGI:1933382|Ensembl:ENSMUSG00000060591|Vega:OTTMUSG00000060381 +80877 Lrba MGI:MGI:1933162|Ensembl:ENSMUSG00000028080|Vega:OTTMUSG00000051661 +80879 Slc16a3 MGI:MGI:1933438|Ensembl:ENSMUSG00000025161|Vega:OTTMUSG00000004161 +80880 Kank3 MGI:MGI:1098615|Ensembl:ENSMUSG00000042099|Vega:OTTMUSG00000037208 +80883 Ntng1 MGI:MGI:1934028|Ensembl:ENSMUSG00000059857|Vega:OTTMUSG00000007362 +80884 Maged2 MGI:MGI:1933391|Ensembl:ENSMUSG00000025268|Vega:OTTMUSG00000019174 +80885 Hcar2 MGI:MGI:1933383|Ensembl:ENSMUSG00000045502|Vega:OTTMUSG00000054742 +80886 Senp3 MGI:MGI:2158736|Ensembl:ENSMUSG00000005204|Vega:OTTMUSG00000006011 +80888 Hspb8 MGI:MGI:2135756|Ensembl:ENSMUSG00000041548|Vega:OTTMUSG00000014696 +80889 Tlnrd1 MGI:MGI:1891420|Ensembl:ENSMUSG00000070462|Vega:OTTMUSG00000030367 +80890 Trim2 MGI:MGI:1933163|Ensembl:ENSMUSG00000027993|Vega:OTTMUSG00000017469 +80891 Fcrls MGI:MGI:1933397|Ensembl:ENSMUSG00000015852|Vega:OTTMUSG00000027492 +80892 Zfhx4 MGI:MGI:2137668|Ensembl:ENSMUSG00000025255|Vega:OTTMUSG00000041080 +80893 Tmprss5 MGI:MGI:1933407|Ensembl:ENSMUSG00000032268|Vega:OTTMUSG00000036070 +80898 Erap1 MGI:MGI:1933403|Ensembl:ENSMUSG00000021583 +80901 Cxcr6 MGI:MGI:1934582|Ensembl:ENSMUSG00000048521|Vega:OTTMUSG00000062909 +80902 Zfp202 MGI:MGI:1933401|Ensembl:ENSMUSG00000025602|Vega:OTTMUSG00000035370 +80903 Fgf16 MGI:MGI:1931627|Ensembl:ENSMUSG00000031230|Vega:OTTMUSG00000018263 +80904 Dtx3 MGI:MGI:2135752|Ensembl:ENSMUSG00000040415|Vega:OTTMUSG00000033472 +80905 Polh MGI:MGI:1891457|Ensembl:ENSMUSG00000023953 +80906 Kcnip2 MGI:MGI:2135916|Ensembl:ENSMUSG00000025221|Vega:OTTMUSG00000035101 +80907 Lactb MGI:MGI:1933395|Ensembl:ENSMUSG00000032370|Vega:OTTMUSG00000062650 +80908 Abo MGI:MGI:2135738|Ensembl:ENSMUSG00000015787|Vega:OTTMUSG00000011583 +80909 Gatsl2 MGI:MGI:1933384|Ensembl:ENSMUSG00000015944|Vega:OTTMUSG00000024547 +80910 Gpr84 MGI:MGI:1934129|Ensembl:ENSMUSG00000063234 +80911 Acox3 MGI:MGI:1933156|Ensembl:ENSMUSG00000029098|Vega:OTTMUSG00000023571 +80912 Pum1 MGI:MGI:1931749|Ensembl:ENSMUSG00000028580|Vega:OTTMUSG00000009596 +80913 Pum2 MGI:MGI:1931751|Ensembl:ENSMUSG00000020594|Vega:OTTMUSG00000035455 +80914 Uck2 MGI:MGI:1931744|Ensembl:ENSMUSG00000026558|Vega:OTTMUSG00000050631 +80915 Dusp12 MGI:MGI:1890614|Ensembl:ENSMUSG00000026659|Vega:OTTMUSG00000035839 +80976 Syt13 MGI:MGI:1933945|Ensembl:ENSMUSG00000027220|Vega:OTTMUSG00000014492 +80978 Mrgprh MGI:MGI:1934134|Ensembl:ENSMUSG00000059408 +80979 Slc26a5 MGI:MGI:1933154|Ensembl:ENSMUSG00000029015|Vega:OTTMUSG00000023668 +80981 Arl4d MGI:MGI:1933155|Ensembl:ENSMUSG00000034936|Vega:OTTMUSG00000014383 +80982 Cemip MGI:MGI:2443629|Ensembl:ENSMUSG00000052353|Vega:OTTMUSG00000025454 +80985 Trim44 MGI:MGI:1931835|Ensembl:ENSMUSG00000027189|Vega:OTTMUSG00000014822 +80986 Ckap2 MGI:MGI:1931797|Ensembl:ENSMUSG00000037725|Vega:OTTMUSG00000060881 +80987 Nckipsd MGI:MGI:1931834|Ensembl:ENSMUSG00000032598|Vega:OTTMUSG00000050675 +81000 Rad54l2 MGI:MGI:1933196|Ensembl:ENSMUSG00000040661|Vega:OTTMUSG00000049429 +81003 Trim23 MGI:MGI:1933161|Ensembl:ENSMUSG00000021712|Vega:OTTMUSG00000035058 +81004 Tbl1xr1 MGI:MGI:2441730|Ensembl:ENSMUSG00000027630|Vega:OTTMUSG00000051127 +81006 Gpr63 MGI:MGI:2135884|Ensembl:ENSMUSG00000040372|Vega:OTTMUSG00000004831 +81007 Defb5 MGI:MGI:1933153|Ensembl:ENSMUSG00000039785|Vega:OTTMUSG00000020669 +81010 Vmn1r172 MGI:MGI:3033478|Ensembl:ENSMUSG00000035523|Vega:OTTMUSG00000038005 +81011 Vmn1r148 MGI:MGI:3033483|Ensembl:ENSMUSG00000095543|Vega:OTTMUSG00000038056 +81012 Vmn1r171 MGI:MGI:3033476|Ensembl:ENSMUSG00000062483|Vega:OTTMUSG00000038004 +81013 Vmn1r65 MGI:MGI:3033475|Ensembl:ENSMUSG00000066850|Vega:OTTMUSG00000037788 +81014 Vmn1r58 MGI:MGI:3033473|Ensembl:ENSMUSG00000078808|Vega:OTTMUSG00000037741 +81015 Vmn1r56 MGI:MGI:3033472|Ensembl:ENSMUSG00000091874|Vega:OTTMUSG00000037737 +81016 Vmn1r62 MGI:MGI:3033471|Ensembl:ENSMUSG00000092579|Vega:OTTMUSG00000037785 +81017 Vmn1r63 MGI:MGI:3033470|Ensembl:ENSMUSG00000058631|Vega:OTTMUSG00000037786 +81018 Rnf114 MGI:MGI:1933159|Ensembl:ENSMUSG00000006418|Vega:OTTMUSG00000001140 +81489 Dnajb1 MGI:MGI:1931874|Ensembl:ENSMUSG00000005483|Vega:OTTMUSG00000061608 +81497 Btnl5-ps MGI:MGI:1932037 +81500 Sil1 MGI:MGI:1932040|Ensembl:ENSMUSG00000024357 +81535 Sgpp1 MGI:MGI:2135760|Ensembl:ENSMUSG00000021054 +81600 Chia1 MGI:MGI:1932052|Ensembl:ENSMUSG00000062778|Vega:OTTMUSG00000023684 +81601 Kat5 MGI:MGI:1932051|Ensembl:ENSMUSG00000024926 +81630 Zbtb22 MGI:MGI:1931870|Ensembl:ENSMUSG00000051390|Vega:OTTMUSG00000037069 +81701 Egfl8 MGI:MGI:1932094|Ensembl:ENSMUSG00000015467|Vega:OTTMUSG00000035858 +81702 Ankrd17 MGI:MGI:1932101|Ensembl:ENSMUSG00000055204|Vega:OTTMUSG00000055446 +81703 Jdp2 MGI:MGI:1932093|Ensembl:ENSMUSG00000034271 +81798 Urml MGI:MGI:1932124 +81799 C1qtnf3 MGI:MGI:1932136|Ensembl:ENSMUSG00000058914|Vega:OTTMUSG00000023906 +81840 Sorcs2 MGI:MGI:1932289|Ensembl:ENSMUSG00000029093|Vega:OTTMUSG00000028018 +81842 Ierepo2 MGI:MGI:1932271 +81845 Gpank1 MGI:MGI:2148975|Ensembl:ENSMUSG00000092417|Vega:OTTMUSG00000037177 +81877 Tnxb MGI:MGI:1932137|Ensembl:ENSMUSG00000033327|Vega:OTTMUSG00000037253 +81879 Tfcp2l1 MGI:MGI:2444691|Ensembl:ENSMUSG00000026380|Vega:OTTMUSG00000049007 +81896 Ift122 MGI:MGI:1932386|Ensembl:ENSMUSG00000030323|Vega:OTTMUSG00000023171 +81897 Tlr9 MGI:MGI:1932389|Ensembl:ENSMUSG00000045322|Vega:OTTMUSG00000049422 +81898 Sf3b1 MGI:MGI:1932339|Ensembl:ENSMUSG00000025982|Vega:OTTMUSG00000046964 +81904 Cacng7 MGI:MGI:1932374|Ensembl:ENSMUSG00000069806|Vega:OTTMUSG00000057715 +81905 Cacng8 MGI:MGI:1932376|Ensembl:ENSMUSG00000053395|Vega:OTTMUSG00000044343 +81906 Cyp4x1 MGI:MGI:1932403|Ensembl:ENSMUSG00000047155|Vega:OTTMUSG00000008620 +81907 Tmem108 MGI:MGI:1932411|Ensembl:ENSMUSG00000042757|Vega:OTTMUSG00000048461 +81909 Zfpl1 MGI:MGI:1891017|Ensembl:ENSMUSG00000024792|Vega:OTTMUSG00000028976 +81910 Rrbp1 MGI:MGI:1932395|Ensembl:ENSMUSG00000027422|Vega:OTTMUSG00000003227 +81912 DXUalb1 MGI:MGI:1890598 +81913 Bambi-ps1 MGI:MGI:1932402 +83379 Klb MGI:MGI:1932466|Ensembl:ENSMUSG00000029195|Vega:OTTMUSG00000028376 +83380 Prp2 MGI:MGI:1932491|Ensembl:ENSMUSG00000058295|Vega:OTTMUSG00000034591 +83382 Siglece MGI:MGI:1932475|Ensembl:ENSMUSG00000030474|Vega:OTTMUSG00000058306 +83383 Tfap4 MGI:MGI:103239|Ensembl:ENSMUSG00000005718 +83395 Sp6 MGI:MGI:1932575|Ensembl:ENSMUSG00000038560|Vega:OTTMUSG00000001859 +83396 Glis2 MGI:MGI:1932535|Ensembl:ENSMUSG00000014303|Vega:OTTMUSG00000026679 +83397 Akap12 MGI:MGI:1932576|Ensembl:ENSMUSG00000038587|Vega:OTTMUSG00000063494 +83398 Ndst3 MGI:MGI:1932544|Ensembl:ENSMUSG00000027977|Vega:OTTMUSG00000025124 +83408 Gimap3 MGI:MGI:1932723|Ensembl:ENSMUSG00000039264|Vega:OTTMUSG00000057387 +83409 Lamtor2 MGI:MGI:1932697|Ensembl:ENSMUSG00000028062|Vega:OTTMUSG00000028880 +83410 Cstf2t MGI:MGI:1932622|Ensembl:ENSMUSG00000053536 +83428 Ucn3 MGI:MGI:1932970|Ensembl:ENSMUSG00000044988 +83429 Ctns MGI:MGI:1932872|Ensembl:ENSMUSG00000005949|Vega:OTTMUSG00000006124 +83430 Il23a MGI:MGI:1932410|Ensembl:ENSMUSG00000025383 +83431 Ndel1 MGI:MGI:1932915|Ensembl:ENSMUSG00000018736|Vega:OTTMUSG00000005956 +83433 Trem2 MGI:MGI:1913150|Ensembl:ENSMUSG00000023992|Vega:OTTMUSG00000021045 +83434 Rsph6a MGI:MGI:1927643|Ensembl:ENSMUSG00000040866|Vega:OTTMUSG00000022697 +83435 Plekha3 MGI:MGI:1932515|Ensembl:ENSMUSG00000002733|Vega:OTTMUSG00000013129 +83436 Plekha2 MGI:MGI:1928144|Ensembl:ENSMUSG00000031557|Vega:OTTMUSG00000022381 +83437 Pgam1-ps1 MGI:MGI:1933119 +83453 Chrdl1 MGI:MGI:1933172|Ensembl:ENSMUSG00000031283|Vega:OTTMUSG00000018903 +83454 Nxf2 MGI:MGI:1933192|Ensembl:ENSMUSG00000009941|Vega:OTTMUSG00000018751 +83456 Mov10l1 MGI:MGI:1891384|Ensembl:ENSMUSG00000015365|Vega:OTTMUSG00000024857 +83457 Fthl17e MGI:MGI:1933180|Ensembl:ENSMUSG00000071815|Vega:OTTMUSG00000017481 +83485 Ngrn MGI:MGI:1933212|Ensembl:ENSMUSG00000047084|Vega:OTTMUSG00000029559 +83486 Rbm5 MGI:MGI:1933204|Ensembl:ENSMUSG00000032580|Vega:OTTMUSG00000043551 +83490 Pik3ap1 MGI:MGI:1933177|Ensembl:ENSMUSG00000025017 +83491 Pramel1 MGI:MGI:1890541|Ensembl:ENSMUSG00000041805|Vega:OTTMUSG00000010134 +83492 Gsdmc MGI:MGI:1933176|Ensembl:ENSMUSG00000079025|Vega:OTTMUSG00000037056 +83493 Sacm1l MGI:MGI:1933169|Ensembl:ENSMUSG00000025240|Vega:OTTMUSG00000062851 +83494 Phgdh-ps1 MGI:MGI:1933203 +83553 Tktl1 MGI:MGI:1933244|Ensembl:ENSMUSG00000031397|Vega:OTTMUSG00000017645 +83554 Fstl3 MGI:MGI:1890391|Ensembl:ENSMUSG00000020325|Vega:OTTMUSG00000035143 +83555 Tex13b MGI:MGI:1890544|Ensembl:ENSMUSG00000042386|Vega:OTTMUSG00000018914 +83556 Tex16 MGI:MGI:1890545|Ensembl:ENSMUSG00000034555|Vega:OTTMUSG00000018437 +83557 Lin28a MGI:MGI:1890546|Ensembl:ENSMUSG00000050966|Vega:OTTMUSG00000010211 +83558 Tex11 MGI:MGI:1933237|Ensembl:ENSMUSG00000009670|Vega:OTTMUSG00000018300 +83559 Tex18 MGI:MGI:1890547 +83560 Tex14 MGI:MGI:1933227|Ensembl:ENSMUSG00000010342|Vega:OTTMUSG00000001260 +83561 Tdrd1 MGI:MGI:1933218|Ensembl:ENSMUSG00000025081|Vega:OTTMUSG00000028359 +83563 Usp26 MGI:MGI:1933247|Ensembl:ENSMUSG00000055780|Vega:OTTMUSG00000017331 +83564 Nlrp4c MGI:MGI:1890518|Ensembl:ENSMUSG00000034690|Vega:OTTMUSG00000029734 +83565 Pramel3 MGI:MGI:1890657|Ensembl:ENSMUSG00000067360|Vega:OTTMUSG00000018758 +83602 Gtf2a1 MGI:MGI:1933277|Ensembl:ENSMUSG00000020962|Vega:OTTMUSG00000035545 +83603 Elovl4 MGI:MGI:1933331|Ensembl:ENSMUSG00000032262|Vega:OTTMUSG00000044946 +83669 Wdr6 MGI:MGI:1930140|Ensembl:ENSMUSG00000066357|Vega:OTTMUSG00000050766 +83671 Sytl2 MGI:MGI:1933366|Ensembl:ENSMUSG00000030616|Vega:OTTMUSG00000049044 +83672 Sytl3 MGI:MGI:1933367|Ensembl:ENSMUSG00000041831|Vega:OTTMUSG00000034273 +83673 Snhg1 MGI:MGI:3763743|Ensembl:ENSMUSG00000108414 +83674 Cnnm1 MGI:MGI:1891366|Ensembl:ENSMUSG00000025189 +83675 Bicc1 MGI:MGI:1933388|Ensembl:ENSMUSG00000014329|Vega:OTTMUSG00000024769 +83677 Usmg2 MGI:MGI:1891432 +83679 Pde4dip MGI:MGI:1891434|Ensembl:ENSMUSG00000038170|Vega:OTTMUSG00000040172 +83691 Crispld1 MGI:MGI:1934666|Ensembl:ENSMUSG00000025776|Vega:OTTMUSG00000029743 +83701 Srrt MGI:MGI:1933527|Ensembl:ENSMUSG00000037364|Vega:OTTMUSG00000054484 +83702 Akr1c6 MGI:MGI:1933427|Ensembl:ENSMUSG00000021210|Vega:OTTMUSG00000027687 +83703 Dbr1 MGI:MGI:1931520|Ensembl:ENSMUSG00000032469|Vega:OTTMUSG00000034138 +83704 Slc12a9 MGI:MGI:1933532|Ensembl:ENSMUSG00000037344|Vega:OTTMUSG00000021935 +83762 Otof MGI:MGI:1891247|Ensembl:ENSMUSG00000062372|Vega:OTTMUSG00000025902 +83766 Actl6b MGI:MGI:1933548|Ensembl:ENSMUSG00000029712|Vega:OTTMUSG00000021924 +83767 Wasf1 MGI:MGI:1890563|Ensembl:ENSMUSG00000019831|Vega:OTTMUSG00000020871 +83768 Dpp7 MGI:MGI:1933213|Ensembl:ENSMUSG00000026958|Vega:OTTMUSG00000011997 +83770 Tas1r2 MGI:MGI:1933546|Ensembl:ENSMUSG00000028738|Vega:OTTMUSG00000010062 +83771 Tas1r3 MGI:MGI:1933547|Ensembl:ENSMUSG00000029072|Vega:OTTMUSG00000010892 +83772 H2-D MGI:MGI:1933561 +83796 Smarcd2 MGI:MGI:1933621|Ensembl:ENSMUSG00000078619|Vega:OTTMUSG00000003421 +83797 Smarcd1 MGI:MGI:1933623|Ensembl:ENSMUSG00000023018 +83813 Tnk1 MGI:MGI:1930958|Ensembl:ENSMUSG00000001583|Vega:OTTMUSG00000006012 +83814 Nedd4l MGI:MGI:1933754|Ensembl:ENSMUSG00000024589 +83815 Cenpq MGI:MGI:1933744|Ensembl:ENSMUSG00000023919|Vega:OTTMUSG00000033029 +83885 Slc25a2 MGI:MGI:2137907|Ensembl:ENSMUSG00000050304|Vega:OTTMUSG00000050775 +83921 Tmem2 MGI:MGI:1890373|Ensembl:ENSMUSG00000024754 +83922 Cep41 MGI:MGI:1891414|Ensembl:ENSMUSG00000029790|Vega:OTTMUSG00000014400 +83924 Gpr137b MGI:MGI:1891463|Ensembl:ENSMUSG00000021306 +83925 Trps1 MGI:MGI:1927616|Ensembl:ENSMUSG00000038679|Vega:OTTMUSG00000044609 +83945 Dnaja3 MGI:MGI:1933786|Ensembl:ENSMUSG00000004069|Vega:OTTMUSG00000024742 +83946 Phip MGI:MGI:1932404|Ensembl:ENSMUSG00000032253|Vega:OTTMUSG00000044899 +83961 Nrg4 MGI:MGI:1933833|Ensembl:ENSMUSG00000032311|Vega:OTTMUSG00000024543 +83962 Btbd1 MGI:MGI:1933765|Ensembl:ENSMUSG00000025103|Vega:OTTMUSG00000059194 +83964 Jam3 MGI:MGI:1933825|Ensembl:ENSMUSG00000031990|Vega:OTTMUSG00000036713 +83965 Enpp5 MGI:MGI:1933830|Ensembl:ENSMUSG00000023960|Vega:OTTMUSG00000028305 +83984 Tssk6 MGI:MGI:2148775|Ensembl:ENSMUSG00000047654|Vega:OTTMUSG00000050077 +83993 Tbx19 MGI:MGI:1891158|Ensembl:ENSMUSG00000026572|Vega:OTTMUSG00000034848 +83995 Mmp1a MGI:MGI:1933846|Ensembl:ENSMUSG00000043089|Vega:OTTMUSG00000062271 +83996 Mmp1b MGI:MGI:1933847|Ensembl:ENSMUSG00000041620|Vega:OTTMUSG00000027386 +83997 Slmap MGI:MGI:1933549|Ensembl:ENSMUSG00000021870|Vega:OTTMUSG00000016367 +84004 Mcam MGI:MGI:1933966|Ensembl:ENSMUSG00000032135|Vega:OTTMUSG00000016731 +84035 Kremen1 MGI:MGI:1933988|Ensembl:ENSMUSG00000020393|Vega:OTTMUSG00000005082 +84036 Kcnn1 MGI:MGI:1933993|Ensembl:ENSMUSG00000002908|Vega:OTTMUSG00000061581 +84092 Usp8 MGI:MGI:1934029|Ensembl:ENSMUSG00000027363|Vega:OTTMUSG00000015864 +84094 Plvap MGI:MGI:1890497|Ensembl:ENSMUSG00000034845|Vega:OTTMUSG00000062158 +84095 Pi4k2a MGI:MGI:1934031|Ensembl:ENSMUSG00000025178 +84111 Gpr87 MGI:MGI:1934133|Ensembl:ENSMUSG00000051431|Vega:OTTMUSG00000052368 +84112 Sucnr1 MGI:MGI:1934135|Ensembl:ENSMUSG00000027762|Vega:OTTMUSG00000051954 +84113 Ptov1 MGI:MGI:1933946|Ensembl:ENSMUSG00000038502|Vega:OTTMUSG00000029494 +84505 Setdb1 MGI:MGI:1934229|Ensembl:ENSMUSG00000015697|Vega:OTTMUSG00000046460 +84506 Hamp MGI:MGI:1933533|Ensembl:ENSMUSG00000050440|Vega:OTTMUSG00000058034 +84543 Sval2 MGI:MGI:1934254|Ensembl:ENSMUSG00000014104|Vega:OTTMUSG00000026916 +84544 Cd96 MGI:MGI:1934368|Ensembl:ENSMUSG00000022657|Vega:OTTMUSG00000017051 +84568 31.MMHAP38FLC4 MGI:MGI:1934222 +84585 Rnf123 MGI:MGI:2148796|Ensembl:ENSMUSG00000041528|Vega:OTTMUSG00000033727 +84652 Fam126a MGI:MGI:2149839|Ensembl:ENSMUSG00000028995|Vega:OTTMUSG00000021289 +84653 Hes7 MGI:MGI:2135679|Ensembl:ENSMUSG00000023781|Vega:OTTMUSG00000005971 +84682 Cox4i2 MGI:MGI:2135755|Ensembl:ENSMUSG00000009876|Vega:OTTMUSG00000015832 +84704 Snurf MGI:MGI:1891236|Ensembl:ENSMUSG00000000948|Ensembl:ENSMUSG00000102627|Vega:OTTMUSG00000042350|Vega:OTTMUSG00000046327 +85029 Rpph1 MGI:MGI:1934664|Ensembl:ENSMUSG00000092837 +85030 Tnfrsf25 MGI:MGI:1934667|Ensembl:ENSMUSG00000024793|Vega:OTTMUSG00000010224 +85031 Pla1a MGI:MGI:1934677|Ensembl:ENSMUSG00000002847 +85034 D2Mit2 MGI:MGI:92064 +85035 D2Mit4 MGI:MGI:92176 +85036 D4Mit2 MGI:MGI:92830 +85037 D9Mit1 MGI:MGI:94610 +85038 D2Mit9 MGI:MGI:92227 +85039 D9Mit9 MGI:MGI:94782 +85040 DXMit4 MGI:MGI:95113 +85041 D3Mit60 MGI:MGI:92531 +85042 D4Mit18 MGI:MGI:92808 +85043 D4Mit19 MGI:MGI:92819 +85044 D4Mit99 MGI:MGI:92936 +85045 D6Mit51 MGI:MGI:93683 +85046 D6Mit85 MGI:MGI:93718 +85047 D7Mit65 MGI:MGI:94086 +85048 D7Mit77 MGI:MGI:94099 +85049 DXMit1.1 MGI:MGI:95058 +85050 DXMit52 MGI:MGI:95127 +85051 DXMit56 MGI:MGI:95131 +85052 D13Mit1 MGI:MGI:89634 +85053 D1Mit20 MGI:MGI:91578 +85054 D1Mit22 MGI:MGI:91600 +85055 D1Mit23 MGI:MGI:91611 +85056 D1Mit34 MGI:MGI:91686 +85057 D1Mit81 MGI:MGI:91733 +85058 D1Mit92 MGI:MGI:91745 +85059 D2Mit13 MGI:MGI:91988 +85060 D2Mit79 MGI:MGI:92215 +85061 D2Mit90 MGI:MGI:92228 +85062 D3Mit51 MGI:MGI:92521 +85063 D4Mit49 MGI:MGI:92882 +85064 D4Mit55 MGI:MGI:92889 +85065 D4Mit57 MGI:MGI:92891 +85066 D4Mit89 MGI:MGI:92925 +85067 D4Mit94 MGI:MGI:92931 +85068 D5Mit34 MGI:MGI:93338 +85069 D5Mit77 MGI:MGI:93378 +85070 D6Mit74 MGI:MGI:93706 +85071 D6Mit94 MGI:MGI:93728 +85072 D7Mit34 MGI:MGI:94061 +85073 D12Mit1009 MGI:MGI:94063 +85074 D7Mit37 MGI:MGI:94064 +85075 D7Mit78 MGI:MGI:94100 +85076 D7Mit86 MGI:MGI:94109 +85077 D7Mit91 MGI:MGI:94115 +85078 D8Mit77 MGI:MGI:94445 +85079 D9Mit14 MGI:MGI:94647 +85080 D9Mit76 MGI:MGI:94768 +85081 D8Mit1007 MGI:MGI:94785 +85082 DXMit66 MGI:MGI:95141 +85083 DXMit69 MGI:MGI:95144 +85084 DXMit71 MGI:MGI:95147 +85085 DXMit74 MGI:MGI:95150 +85086 DXMit78 MGI:MGI:95154 +85087 DXMit93 MGI:MGI:95170 +85088 D15Mit7 MGI:MGI:90352 +85089 D16Mit2 MGI:MGI:90492 +85090 D1Mit17 MGI:MGI:91545 +85091 D2Mit231 MGI:MGI:92098 +85092 D5Mit178 MGI:MGI:93254 +85093 D7Mit114 MGI:MGI:93930 +85094 D7Mit63 MGI:MGI:94084 +85095 D6Mit1004 MGI:MGI:94681 +85096 DXMit163 MGI:MGI:99985 +85097 DXMit137 MGI:MGI:100011 +85098 D7Mit264 MGI:MGI:100249 +85099 D5Mit250 MGI:MGI:100466 +85100 D7Mit305 MGI:MGI:102144 +85101 DXMit190 MGI:MGI:102452 +85102 D7Mit339 MGI:MGI:105489 +85103 D1Mit493 MGI:MGI:105639 +85104 D1Mit499 MGI:MGI:105645 +85105 DXMit211 MGI:MGI:105904 +85106 D12Mit11 MGI:MGI:89354 +85107 D12Mit43 MGI:MGI:89451 +85108 D12Mit81 MGI:MGI:89491 +85109 D13Mit80 MGI:MGI:89809 +85110 D15Mit12 MGI:MGI:90250 +85111 D16Mit10 MGI:MGI:90455 +85112 D17Mit48 MGI:MGI:90837 +85113 D18Mit19 MGI:MGI:91070 +85114 D18Mit20 MGI:MGI:91072 +85115 D18Mit32 MGI:MGI:91084 +85116 D19Mit42 MGI:MGI:91253 +85117 D5Mit1003 MGI:MGI:91500 +85118 D1Mit225 MGI:MGI:91606 +85119 D1Mit235 MGI:MGI:91617 +85120 D3Mit107 MGI:MGI:92372 +85121 D3Mit133 MGI:MGI:92401 +85122 D4Mit139 MGI:MGI:92763 +85123 D4Mit165 MGI:MGI:92792 +85124 D5Mit106 MGI:MGI:93175 +85125 D1Mit1009 MGI:MGI:93178 +85126 D5Mit128 MGI:MGI:93199 +85127 D5Mit130 MGI:MGI:93202 +85128 D7Mit156 MGI:MGI:93976 +85129 D7Mit202 MGI:MGI:94026 +85130 D8Mit129 MGI:MGI:94308 +85131 D9Mit139 MGI:MGI:94646 +85132 D9Mit167 MGI:MGI:94677 +85133 DXMit106 MGI:MGI:95066 +85134 DXMit173 MGI:MGI:99975 +85135 DXMit155 MGI:MGI:99993 +85136 DXMit147 MGI:MGI:100001 +85137 DXMit131 MGI:MGI:100017 +85138 D9Mit282 MGI:MGI:100041 +85139 D9Mit260 MGI:MGI:100063 +85140 D7Mit302 MGI:MGI:100211 +85141 D7Mit295 MGI:MGI:100218 +85142 D6Mit299 MGI:MGI:100295 +85143 D6Mit250 MGI:MGI:100344 +85144 D5Mit304 MGI:MGI:100412 +85145 D5Mit254 MGI:MGI:100462 +85146 D4Mit256 MGI:MGI:100503 +85147 D3Mit249 MGI:MGI:100586 +85148 D3Mit246 MGI:MGI:100589 +85149 D2Mit319 MGI:MGI:100720 +85150 D1Mit393 MGI:MGI:101373 +85151 D1Mit388 MGI:MGI:101378 +85152 D1Mit377 MGI:MGI:101389 +85153 D1Mit344 MGI:MGI:101422 +85154 D1Mit309 MGI:MGI:101457 +85155 D1Mit308 MGI:MGI:101458 +85156 D5Mit358 MGI:MGI:102085 +85157 D6Mit317 MGI:MGI:102120 +85158 D6Mit332 MGI:MGI:102134 +85159 DXMit222 MGI:MGI:104339 +85160 D6Mit358 MGI:MGI:105522 +85161 D4Mit331 MGI:MGI:105601 +85162 D4Mit324 MGI:MGI:105608 +85163 D1Mit530 MGI:MGI:107040 +85164 DXMit1001 MGI:MGI:107100 +85165 D6Mit390 MGI:MGI:107114 +85166 D8Mit357 MGI:MGI:107126 +85167 DXMit226 MGI:MGI:107144 +85168 DXMit233 MGI:MGI:107151 +85169 D11Mit42 MGI:MGI:89126 +85170 D12Mit36 MGI:MGI:89446 +85171 D12Mit61 MGI:MGI:89469 +85172 D12Mit86 MGI:MGI:89496 +85173 D13Mit54 MGI:MGI:89781 +85174 D10Mit1011 MGI:MGI:89794 +85175 D13Mit82 MGI:MGI:89811 +85176 D13Mit83 MGI:MGI:89812 +85177 D14Mit35 MGI:MGI:90039 +85178 D14Mit77 MGI:MGI:90084 +85179 D14Mit92 MGI:MGI:90100 +85180 D16Mit15 MGI:MGI:90489 +85181 D16Mit47 MGI:MGI:90517 +85182 D16Mit69 MGI:MGI:90541 +85183 D16Mit77 MGI:MGI:90550 +85184 D17Mit59 MGI:MGI:90849 +85185 D17Mit79 MGI:MGI:90870 +85186 D18Mit27 MGI:MGI:91078 +85187 D18Mit85 MGI:MGI:91142 +85188 D19Mit34 MGI:MGI:91244 +85189 D1Mit223 MGI:MGI:91604 +85190 D19Mit95 MGI:MGI:100752 +85191 D19Mit88 MGI:MGI:100759 +85192 D1Mit460 MGI:MGI:101990 +85193 D11Mit150 MGI:MGI:89035 +85194 D11Mit95 MGI:MGI:89175 +85195 D18Mit110 MGI:MGI:91028 +85196 D18Mit167 MGI:MGI:100809 +85197 D18Mit164 MGI:MGI:100812 +85198 D13Mit264 MGI:MGI:101071 +85199 D13Mit235 MGI:MGI:101100 +85200 D13Mit205 MGI:MGI:101130 +85201 D11Mit259 MGI:MGI:101232 +85202 D13Mit1004 MGI:MGI:105400 +85203 D17Mit245 MGI:MGI:105420 +85204 D10Mit297 MGI:MGI:105803 +85205 D11Mit343 MGI:MGI:105804 +85206 D15Mit251 MGI:MGI:105861 +85207 D10Mit151 MGI:MGI:88771 +85208 D11Mit124 MGI:MGI:89006 +85209 D12Mit115 MGI:MGI:89360 +85210 D13Mit131 MGI:MGI:89669 +85211 D14Mit165 MGI:MGI:90008 +85212 D15Mit111 MGI:MGI:90241 +85213 D17Mit133 MGI:MGI:90774 +85214 D17Mit154 MGI:MGI:90795 +85215 D17Mit162 MGI:MGI:90804 +85216 D18Mit102 MGI:MGI:91020 +85217 D18Mit106 MGI:MGI:91024 +85218 D18Mit180 MGI:MGI:100796 +85219 D17Mit197 MGI:MGI:100855 +85220 D16Mit171 MGI:MGI:100910 +85221 D15Mit163 MGI:MGI:101012 +85222 D15Mit162 MGI:MGI:101013 +85223 D13Mit214 MGI:MGI:101121 +85224 D11Mit262 MGI:MGI:101229 +85225 D11Mit242 MGI:MGI:101249 +85226 D10Mit196 MGI:MGI:101324 +85227 D10Mit270 MGI:MGI:102268 +85228 D16Mit204 MGI:MGI:102402 +85229 D17Mit241 MGI:MGI:102423 +85230 D17Mit244 MGI:MGI:102425 +85231 D18Mit224 MGI:MGI:105399 +85232 D16Mit221 MGI:MGI:106962 +85233 D18Mit231 MGI:MGI:106974 +85234 D16Mit205 MGI:MGI:102403 +85305 Kars MGI:MGI:1934754|Ensembl:ENSMUSG00000031948|Vega:OTTMUSG00000061807 +85307 Kars-ps1 MGI:MGI:1934756 +85308 Emc9 MGI:MGI:1934682|Ensembl:ENSMUSG00000022217|Vega:OTTMUSG00000037637 +89867 Sec16b MGI:MGI:2148802|Ensembl:ENSMUSG00000026589|Vega:OTTMUSG00000022599 +93670 Tac4 MGI:MGI:1931130|Ensembl:ENSMUSG00000020872|Vega:OTTMUSG00000001620 +93671 Cd163 MGI:MGI:2135946|Ensembl:ENSMUSG00000008845|Vega:OTTMUSG00000056662 +93672 Il24 MGI:MGI:2135548|Ensembl:ENSMUSG00000026420|Vega:OTTMUSG00000028577 +93673 Nat8f2 MGI:MGI:2136446|Ensembl:ENSMUSG00000033634|Vega:OTTMUSG00000034540 +93674 Nat8f3 MGI:MGI:2136449|Ensembl:ENSMUSG00000051262|Vega:OTTMUSG00000034536 +93675 Clec2i MGI:MGI:2136650|Ensembl:ENSMUSG00000030365|Vega:OTTMUSG00000034582 +93677 Lmod2 MGI:MGI:2135672|Ensembl:ENSMUSG00000029683|Vega:OTTMUSG00000056001 +93679 Trim8 MGI:MGI:1933302|Ensembl:ENSMUSG00000025034 +93681 Zkscan8 MGI:MGI:1913815|Ensembl:ENSMUSG00000063894|Vega:OTTMUSG00000000427 +93683 Glce MGI:MGI:2136405|Ensembl:ENSMUSG00000032252|Vega:OTTMUSG00000046492 +93684 Selenof MGI:MGI:1927947|Ensembl:ENSMUSG00000037072|Vega:OTTMUSG00000021251 +93685 Entpd7 MGI:MGI:2135885|Ensembl:ENSMUSG00000025192|Vega:OTTMUSG00000026396 +93686 Rbfox2 MGI:MGI:1933973|Ensembl:ENSMUSG00000033565 +93687 Csnk1a1 MGI:MGI:1934950|Ensembl:ENSMUSG00000024576|Vega:OTTMUSG00000035876 +93688 Klhl1 MGI:MGI:2136335|Ensembl:ENSMUSG00000022076|Vega:OTTMUSG00000023102 +93689 Lmod1 MGI:MGI:2135671|Ensembl:ENSMUSG00000048096|Vega:OTTMUSG00000022119 +93690 Gpr45 MGI:MGI:2135882|Ensembl:ENSMUSG00000041907|Vega:OTTMUSG00000045911 +93691 Klf7 MGI:MGI:1935151|Ensembl:ENSMUSG00000025959|Vega:OTTMUSG00000013919 +93692 Glrx MGI:MGI:2135625|Ensembl:ENSMUSG00000021591|Vega:OTTMUSG00000020964 +93694 Clec2d MGI:MGI:2135589|Ensembl:ENSMUSG00000030157|Vega:OTTMUSG00000029144 +93695 Gpnmb MGI:MGI:1934765|Ensembl:ENSMUSG00000029816|Vega:OTTMUSG00000057401 +93696 Chrac1 MGI:MGI:2135796|Ensembl:ENSMUSG00000068391|Vega:OTTMUSG00000032751 +93697 Ice2 MGI:MGI:2135947|Ensembl:ENSMUSG00000032235|Vega:OTTMUSG00000030929 +93699 Pcdhgb1 MGI:MGI:1935169|Ensembl:ENSMUSG00000103037|Vega:OTTMUSG00000050802 +93700 Pcdhgb2 MGI:MGI:1935170|Ensembl:ENSMUSG00000102748|Vega:OTTMUSG00000050809 +93701 Pcdhgb4 MGI:MGI:1935173|Ensembl:ENSMUSG00000103585|Vega:OTTMUSG00000050814 +93702 Pcdhgb5 MGI:MGI:1935196|Ensembl:ENSMUSG00000103749|Vega:OTTMUSG00000050826 +93703 Pcdhgb6 MGI:MGI:1935197|Ensembl:ENSMUSG00000103088|Vega:OTTMUSG00000050841 +93704 Pcdhgb7 MGI:MGI:1935199|Ensembl:ENSMUSG00000104063|Vega:OTTMUSG00000050844 +93705 Pcdhgb8 MGI:MGI:1935200|Ensembl:ENSMUSG00000103081|Vega:OTTMUSG00000050847 +93706 Pcdhgc3 MGI:MGI:1935201|Ensembl:ENSMUSG00000102918|Vega:OTTMUSG00000050871 +93707 Pcdhgc4 MGI:MGI:1935203|Ensembl:ENSMUSG00000023036|Vega:OTTMUSG00000050873 +93708 Pcdhgc5 MGI:MGI:1935205|Ensembl:ENSMUSG00000102543|Vega:OTTMUSG00000050874 +93709 Pcdhga1 MGI:MGI:1935212|Ensembl:ENSMUSG00000103144|Vega:OTTMUSG00000050779 +93710 Pcdhga2 MGI:MGI:1935214|Ensembl:ENSMUSG00000103332|Vega:OTTMUSG00000050800 +93711 Pcdhga3 MGI:MGI:1935215|Ensembl:ENSMUSG00000104346|Vega:OTTMUSG00000050801 +93712 Pcdhga4 MGI:MGI:1935216|Ensembl:ENSMUSG00000103677|Vega:OTTMUSG00000050808 +93713 Pcdhga5 MGI:MGI:1935217|Ensembl:ENSMUSG00000103567|Vega:OTTMUSG00000050810 +93714 Pcdhga6 MGI:MGI:1935218|Ensembl:ENSMUSG00000103793|Vega:OTTMUSG00000050811 +93715 Pcdhga7 MGI:MGI:1935219|Ensembl:ENSMUSG00000103472|Vega:OTTMUSG00000050812 +93716 Pcdhga8 MGI:MGI:1935221|Ensembl:ENSMUSG00000103897|Vega:OTTMUSG00000050825 +93717 Pcdhga9 MGI:MGI:1935226|Ensembl:ENSMUSG00000102440|Vega:OTTMUSG00000050834 +93719 Ear6 MGI:MGI:1890463|Ensembl:ENSMUSG00000062148|Vega:OTTMUSG00000036430 +93721 Cpn1 MGI:MGI:2135874|Ensembl:ENSMUSG00000025196|Vega:OTTMUSG00000026385 +93722 Pcdhga10 MGI:MGI:1935227|Ensembl:ENSMUSG00000102222|Vega:OTTMUSG00000050842 +93723 Pcdhga11 MGI:MGI:1935228|Ensembl:ENSMUSG00000102742|Vega:OTTMUSG00000050845 +93724 Pcdhga12 MGI:MGI:1935229|Ensembl:ENSMUSG00000102428|Vega:OTTMUSG00000050866 +93725 Ear10 MGI:MGI:1890464|Ensembl:ENSMUSG00000090166|Vega:OTTMUSG00000034649 +93726 Rnase2a MGI:MGI:1890465|Ensembl:ENSMUSG00000047222 +93728 Pabpc5 MGI:MGI:2136401|Ensembl:ENSMUSG00000034732|Vega:OTTMUSG00000018505 +93730 Lztfl1 MGI:MGI:1934860|Ensembl:ENSMUSG00000025245|Vega:OTTMUSG00000035821 +93732 Acox2 MGI:MGI:1934852|Ensembl:ENSMUSG00000021751|Vega:OTTMUSG00000035513 +93734 Mpv17l MGI:MGI:2135951|Ensembl:ENSMUSG00000022679|Vega:OTTMUSG00000028136 +93735 Wnt16 MGI:MGI:2136018|Ensembl:ENSMUSG00000029671|Vega:OTTMUSG00000026889 +93736 Aff4 MGI:MGI:2136171|Ensembl:ENSMUSG00000049470|Vega:OTTMUSG00000000053 +93737 Pard6g MGI:MGI:2135606|Ensembl:ENSMUSG00000056214 +93739 Gabarapl2 MGI:MGI:1890602|Ensembl:ENSMUSG00000031950|Vega:OTTMUSG00000031074 +93742 Pard3 MGI:MGI:2135608|Ensembl:ENSMUSG00000025812|Vega:OTTMUSG00000034639 +93743 Ear-ps2 MGI:MGI:1890466 +93746 Gprc5d MGI:MGI:1935037|Ensembl:ENSMUSG00000030205|Vega:OTTMUSG00000023089 +93747 Echs1 MGI:MGI:2136460|Ensembl:ENSMUSG00000025465|Vega:OTTMUSG00000027297 +93749 Hspe1-ps2 MGI:MGI:1935162 +93751 Hspe1-ps4 MGI:MGI:1935164 +93752 Hspe1-ps5 MGI:MGI:1935166 +93753 Hspe1-ps6 MGI:MGI:1935167 +93757 Immp2l MGI:MGI:2135611|Ensembl:ENSMUSG00000056899|Vega:OTTMUSG00000033105 +93758 Mthfr-rs1 MGI:MGI:2135959 +93759 Sirt1 MGI:MGI:2135607|Ensembl:ENSMUSG00000020063|Vega:OTTMUSG00000030914 +93760 Arid1a MGI:MGI:1935147|Ensembl:ENSMUSG00000007880|Vega:OTTMUSG00000011035 +93761 Smarca1 MGI:MGI:1935127|Ensembl:ENSMUSG00000031099|Vega:OTTMUSG00000017431 +93762 Smarca5 MGI:MGI:1935129|Ensembl:ENSMUSG00000031715|Vega:OTTMUSG00000023886 +93765 Ube2n MGI:MGI:1934835|Ensembl:ENSMUSG00000074781 +93790 Nipa2 MGI:MGI:1913918|Ensembl:ENSMUSG00000030452|Vega:OTTMUSG00000031183 +93806 Serpinb9g MGI:MGI:1919260|Ensembl:ENSMUSG00000057726|Vega:OTTMUSG00000000709 +93834 Peli2 MGI:MGI:1891445|Ensembl:ENSMUSG00000021846 +93835 Amn MGI:MGI:1934943|Ensembl:ENSMUSG00000021278 +93836 Rnf111 MGI:MGI:1934919|Ensembl:ENSMUSG00000032217|Vega:OTTMUSG00000063623 +93837 Dach2 MGI:MGI:1890446|Ensembl:ENSMUSG00000025592|Vega:OTTMUSG00000018671 +93838 Dqx1 MGI:MGI:2136388|Ensembl:ENSMUSG00000009145|Vega:OTTMUSG00000057857 +93840 Vangl2 MGI:MGI:2135272|Ensembl:ENSMUSG00000026556|Vega:OTTMUSG00000021582 +93841 Uchl4 MGI:MGI:1890440|Ensembl:ENSMUSG00000035337|Vega:OTTMUSG00000062593 +93842 Igsf9 MGI:MGI:2135283|Ensembl:ENSMUSG00000037995|Vega:OTTMUSG00000033897 +93843 Pnck MGI:MGI:1347357|Ensembl:ENSMUSG00000002012|Vega:OTTMUSG00000017681 +93844 Hrmt1l2-rs MGI:MGI:2136265 +93846 D1Jor1 MGI:MGI:2135897 +93847 D1Jor2 MGI:MGI:2135898 +93848 D6Jor1 MGI:MGI:2135900 +93849 D6Jor2 MGI:MGI:2135901 +93850 D3Jor1 MGI:MGI:2135903 +93851 D5Jor1 MGI:MGI:2135904 +93852 D8Jor1 MGI:MGI:2135905 +93853 D7Jor1 MGI:MGI:2135906 +93854 D1Jor3 MGI:MGI:2135899 +93855 D15Jor1 MGI:MGI:2135902 +93856 D14Jor1 MGI:MGI:2135907 +93857 D14Jor2 MGI:MGI:2135908 +93858 D10Jor1 MGI:MGI:2135909 +93859 D10Jor2 MGI:MGI:2135910 +93860 D11Jor1 MGI:MGI:2135911 +93861 D18Jor1 MGI:MGI:2135912 +93862 D14Jor3 MGI:MGI:2135913 +93871 Brwd1 MGI:MGI:1890651|Ensembl:ENSMUSG00000022914|Vega:OTTMUSG00000020395 +93872 Pcdhb1 MGI:MGI:2136730|Ensembl:ENSMUSG00000051663|Vega:OTTMUSG00000050662 +93873 Pcdhb2 MGI:MGI:2136735|Ensembl:ENSMUSG00000051599|Vega:OTTMUSG00000050663 +93874 Pcdhb3 MGI:MGI:2136737|Ensembl:ENSMUSG00000045498|Vega:OTTMUSG00000050666 +93875 Pcdhb4 MGI:MGI:2136738|Ensembl:ENSMUSG00000045689|Vega:OTTMUSG00000050701 +93876 Pcdhb5 MGI:MGI:2136739|Ensembl:ENSMUSG00000063687|Vega:OTTMUSG00000050702 +93877 Pcdhb6 MGI:MGI:2136740|Ensembl:ENSMUSG00000051678|Vega:OTTMUSG00000050703 +93878 Pcdhb7 MGI:MGI:2136741|Ensembl:ENSMUSG00000045062|Vega:OTTMUSG00000050720 +93879 Pcdhb8 MGI:MGI:2136742|Ensembl:ENSMUSG00000045876|Vega:OTTMUSG00000050721 +93880 Pcdhb9 MGI:MGI:2136744|Ensembl:ENSMUSG00000051242|Vega:OTTMUSG00000050723 +93881 Pcdhb10 MGI:MGI:2136745|Ensembl:ENSMUSG00000045657|Vega:OTTMUSG00000050724 +93882 Pcdhb11 MGI:MGI:2136746|Ensembl:ENSMUSG00000051486|Vega:OTTMUSG00000050726 +93883 Pcdhb12 MGI:MGI:2136747|Ensembl:ENSMUSG00000043458|Vega:OTTMUSG00000050735 +93884 Pcdhb13 MGI:MGI:2136748|Ensembl:ENSMUSG00000047307|Vega:OTTMUSG00000050736 +93885 Pcdhb14 MGI:MGI:2136749|Ensembl:ENSMUSG00000044043|Vega:OTTMUSG00000050740 +93886 Pcdhb15 MGI:MGI:2136750|Ensembl:ENSMUSG00000047033|Vega:OTTMUSG00000050741 +93887 Pcdhb16 MGI:MGI:2136752|Ensembl:ENSMUSG00000047910|Vega:OTTMUSG00000050742 +93888 Pcdhb17 MGI:MGI:2136754|Ensembl:ENSMUSG00000046387|Vega:OTTMUSG00000050743 +93889 Pcdhb18 MGI:MGI:2136756|Ensembl:ENSMUSG00000048347|Vega:OTTMUSG00000050744 +93890 Pcdhb19 MGI:MGI:2136757|Ensembl:ENSMUSG00000043313|Vega:OTTMUSG00000050745 +93891 Pcdhb20 MGI:MGI:2136758|Ensembl:ENSMUSG00000046191|Vega:OTTMUSG00000050746 +93892 Pcdhb21 MGI:MGI:2136759|Ensembl:ENSMUSG00000044022|Vega:OTTMUSG00000050770 +93893 Pcdhb22 MGI:MGI:2136760|Ensembl:ENSMUSG00000073591|Vega:OTTMUSG00000050772 +93895 Msx1os MGI:MGI:2136762 +93896 Glp2r MGI:MGI:2136733|Ensembl:ENSMUSG00000049928|Vega:OTTMUSG00000005929 +93897 Fzd10 MGI:MGI:2136761|Ensembl:ENSMUSG00000081683|Vega:OTTMUSG00000027707 +93898 Cers1 MGI:MGI:2136690|Ensembl:ENSMUSG00000087408|Vega:OTTMUSG00000034044 +93900 D16Jhu29 MGI:MGI:2136784 +93901 D16Jhu36 MGI:MGI:2136788 +93902 D16Jhu37 MGI:MGI:2136789 +93903 D16Jhu38 MGI:MGI:2136790 +93904 D16Jhu40 MGI:MGI:2136792 +93905 D16Jhu41 MGI:MGI:2136793 +93906 D16Jhu42 MGI:MGI:2136794 +93907 D16Jhu45 MGI:MGI:2136796 +93908 D16Jhu46 MGI:MGI:2136798 +93909 D16Jhu47 MGI:MGI:2136799 +93910 D16Jhu48 MGI:MGI:2136800 +93911 D16Jhu49 MGI:MGI:2136801 +93912 D16Jhu50 MGI:MGI:2136802 +93913 D16Jhu51 MGI:MGI:2136803 +93914 D16Jhu52 MGI:MGI:2136804 +93915 D16Jhu53 MGI:MGI:2136805 +93916 D16Jhu54 MGI:MGI:2136806 +93917 D16Jhu55 MGI:MGI:2136807 +93918 D16Jhu56 MGI:MGI:2136808 +93919 D16Jhu57 MGI:MGI:2136811 +93920 D16Jhu59 MGI:MGI:2136813 +93921 D16Jhu60 MGI:MGI:2136814 +93922 D16Jhu61 MGI:MGI:2136815 +93923 D16Jhu62 MGI:MGI:2136816 +93924 D16Jhu63 MGI:MGI:2136818 +93925 D16Jhu64 MGI:MGI:2136819 +93926 D16Jhu65 MGI:MGI:2136820 +93927 D16Jhu66 MGI:MGI:2136821 +93928 D16Jhu67 MGI:MGI:2136822 +93929 D16Jhu68 MGI:MGI:2136823 +93930 D16Jhu69 MGI:MGI:2136824 +93931 D16Jhu70 MGI:MGI:2136826 +93932 D16Jhu71 MGI:MGI:2136827 +93933 D16Jhu73 MGI:MGI:2136829 +93934 D16Jhu74 MGI:MGI:2136830 +93935 D16Jhu75 MGI:MGI:2136831 +93936 D16Jhu76 MGI:MGI:2136832 +93937 D16Jhu77 MGI:MGI:2136833 +93938 D16Jhu78 MGI:MGI:2136834 +93939 D16Jhu79 MGI:MGI:2136835 +93940 D16Jhu80 MGI:MGI:2136836 +93941 D16Jhu81 MGI:MGI:2136837 +93942 D16Jhu21 MGI:MGI:2136839 +93943 D16Jhu58e MGI:MGI:2136812 +93944 D16Jhu83e MGI:MGI:2136838 +93945 D16Jhu31e MGI:MGI:2136840 +93947 D16Jhu33 MGI:MGI:1338061 +93960 Nkd1 MGI:MGI:2135954|Ensembl:ENSMUSG00000031661|Vega:OTTMUSG00000061474 +93961 B3galt5 MGI:MGI:2136878|Ensembl:ENSMUSG00000074892|Vega:OTTMUSG00000020397 +93966 Hemgn MGI:MGI:2136910|Ensembl:ENSMUSG00000028332|Vega:OTTMUSG00000006887 +93967 Klra20 MGI:MGI:2136937 +93968 Klra21 MGI:MGI:2136938 +93969 Klra22 MGI:MGI:2136939 +93970 Klra18 MGI:MGI:2136935 +93971 Klra19 MGI:MGI:2136936 +94040 Clmn MGI:MGI:2136957|Ensembl:ENSMUSG00000021097 +94041 Allc MGI:MGI:2136971|Ensembl:ENSMUSG00000020636|Vega:OTTMUSG00000023258 +94043 Tm2d1 MGI:MGI:2137022|Ensembl:ENSMUSG00000028563|Vega:OTTMUSG00000008421 +94044 Bcl2l13 MGI:MGI:2136959|Ensembl:ENSMUSG00000009112|Vega:OTTMUSG00000056829 +94045 P2rx5 MGI:MGI:2137026|Ensembl:ENSMUSG00000005950|Vega:OTTMUSG00000006120 +94047 Cecr6 MGI:MGI:2136977|Ensembl:ENSMUSG00000094626|Vega:OTTMUSG00000056822 +94049 Ms10h MGI:MGI:2137043 +94050 Ms10i MGI:MGI:2137045 +94051 Ms10l MGI:MGI:2137046 +94052 Ms10s MGI:MGI:2137050 +94053 Ms10ad MGI:MGI:2137053 +94054 Mdm4-ps MGI:MGI:2136991 +94060 Lce3c MGI:MGI:2135932|Ensembl:ENSMUSG00000045475|Vega:OTTMUSG00000051906 +94061 Mrpl1 MGI:MGI:2137202|Ensembl:ENSMUSG00000029486|Vega:OTTMUSG00000026605 +94062 Mrpl3 MGI:MGI:2137204|Ensembl:ENSMUSG00000032563|Vega:OTTMUSG00000023521 +94063 Mrpl16 MGI:MGI:2137219|Ensembl:ENSMUSG00000024683 +94064 Mrpl27 MGI:MGI:2137224|Ensembl:ENSMUSG00000024414|Vega:OTTMUSG00000002021 +94065 Mrpl34 MGI:MGI:2137227|Ensembl:ENSMUSG00000034880|Vega:OTTMUSG00000062156 +94066 Mrpl36 MGI:MGI:2137228|Ensembl:ENSMUSG00000021607 +94067 Mrpl43 MGI:MGI:2137229|Ensembl:ENSMUSG00000025208 +94068 Ms10n MGI:MGI:2137066 +94069 Ms10o MGI:MGI:2137068 +94071 Clec2h MGI:MGI:2136934|Ensembl:ENSMUSG00000030364|Vega:OTTMUSG00000056390 +94088 Trim6 MGI:MGI:2137352|Ensembl:ENSMUSG00000072244|Vega:OTTMUSG00000019051 +94089 Trim7 MGI:MGI:2137353|Ensembl:ENSMUSG00000040350|Vega:OTTMUSG00000005519 +94090 Trim9 MGI:MGI:2137354|Ensembl:ENSMUSG00000021071 +94091 Trim11 MGI:MGI:2137355|Ensembl:ENSMUSG00000020455|Vega:OTTMUSG00000005778 +94092 Trim16 MGI:MGI:2137356|Ensembl:ENSMUSG00000047821|Vega:OTTMUSG00000005876 +94093 Trim33 MGI:MGI:2137357|Ensembl:ENSMUSG00000033014|Vega:OTTMUSG00000053581 +94094 Trim34a MGI:MGI:2137359|Ensembl:ENSMUSG00000056144|Vega:OTTMUSG00000019147 +94109 Csmd1 MGI:MGI:2137383|Ensembl:ENSMUSG00000060924|Vega:OTTMUSG00000033994 +94111 Mepe MGI:MGI:2137384|Ensembl:ENSMUSG00000053863|Vega:OTTMUSG00000053774 +94112 Med15 MGI:MGI:2137379|Ensembl:ENSMUSG00000012114 +94118 Kifc5c-ps MGI:MGI:2137415 +94175 Hrg MGI:MGI:2146636|Ensembl:ENSMUSG00000022877|Vega:OTTMUSG00000033775 +94176 Dock2 MGI:MGI:2149010|Ensembl:ENSMUSG00000020143|Vega:OTTMUSG00000005408 +94178 Mcoln1 MGI:MGI:1890498|Ensembl:ENSMUSG00000004567|Vega:OTTMUSG00000026357 +94179 Krt23 MGI:MGI:2148866|Ensembl:ENSMUSG00000006777|Vega:OTTMUSG00000004988 +94180 Acsbg1 MGI:MGI:2385656|Ensembl:ENSMUSG00000032281|Vega:OTTMUSG00000030280 +94181 Nans MGI:MGI:2149820|Ensembl:ENSMUSG00000028334|Vega:OTTMUSG00000006890 +94184 Pdxdc1 MGI:MGI:1920909|Ensembl:ENSMUSG00000022680|Vega:OTTMUSG00000024509 +94185 Tnfrsf21 MGI:MGI:2151075|Ensembl:ENSMUSG00000023915 +94186 Strn3 MGI:MGI:2151064|Ensembl:ENSMUSG00000020954 +94187 Zfp423 MGI:MGI:1891217|Ensembl:ENSMUSG00000045333|Vega:OTTMUSG00000036956 +94190 Ophn1 MGI:MGI:2151070|Ensembl:ENSMUSG00000031214|Vega:OTTMUSG00000018075 +94191 Adarb2 MGI:MGI:2151118|Ensembl:ENSMUSG00000052551|Vega:OTTMUSG00000023149 +94192 C1galt1 MGI:MGI:2151071|Ensembl:ENSMUSG00000042460|Vega:OTTMUSG00000023144 +94212 Pag1 MGI:MGI:2443160|Ensembl:ENSMUSG00000027508|Vega:OTTMUSG00000033869 +94213 Ddx50 MGI:MGI:2182303|Ensembl:ENSMUSG00000020076 +94214 Spock2 MGI:MGI:1891351|Ensembl:ENSMUSG00000058297|Vega:OTTMUSG00000029785 +94215 Ugt2a1 MGI:MGI:2149905|Ensembl:ENSMUSG00000106677|Vega:OTTMUSG00000056112 +94216 Col4a6 MGI:MGI:2152695|Ensembl:ENSMUSG00000031273|Vega:OTTMUSG00000018922 +94217 Lrp1b MGI:MGI:2151136|Ensembl:ENSMUSG00000049252|Vega:OTTMUSG00000012311 +94218 Cnnm3 MGI:MGI:2151055|Ensembl:ENSMUSG00000001138|Vega:OTTMUSG00000021763 +94219 Cnnm2 MGI:MGI:2151054|Ensembl:ENSMUSG00000064105 +94220 Cnnm4 MGI:MGI:2151060|Ensembl:ENSMUSG00000037408|Vega:OTTMUSG00000033420 +94221 Gopc MGI:MGI:2149946|Ensembl:ENSMUSG00000019861 +94222 Olig3 MGI:MGI:2149955|Ensembl:ENSMUSG00000045591|Vega:OTTMUSG00000063742 +94223 Dgcr8 MGI:MGI:2151114|Ensembl:ENSMUSG00000022718|Vega:OTTMUSG00000023707 +94224 Srd5a2 MGI:MGI:2150380|Ensembl:ENSMUSG00000038541 +94226 S1pr5 MGI:MGI:2150641|Ensembl:ENSMUSG00000045087|Vega:OTTMUSG00000028855 +94227 Pi15 MGI:MGI:1934659|Ensembl:ENSMUSG00000067780|Vega:OTTMUSG00000048206 +94229 Slc4a10 MGI:MGI:2150150|Ensembl:ENSMUSG00000026904|Vega:OTTMUSG00000012738 +94230 Cpsf1 MGI:MGI:2679722|Ensembl:ENSMUSG00000034022 +94232 Ubqln4 MGI:MGI:2150152|Ensembl:ENSMUSG00000008604|Vega:OTTMUSG00000052160 +94242 Tinagl1 MGI:MGI:2137617|Ensembl:ENSMUSG00000028776|Vega:OTTMUSG00000009561 +94244 Fkbp6 MGI:MGI:2137612|Ensembl:ENSMUSG00000040013|Vega:OTTMUSG00000055918 +94245 Dtnbp1 MGI:MGI:2137586|Ensembl:ENSMUSG00000057531 +94246 Arid4b MGI:MGI:2137512|Ensembl:ENSMUSG00000039219|Vega:OTTMUSG00000018144 +94249 Slc24a3 MGI:MGI:2137513|Ensembl:ENSMUSG00000063873|Vega:OTTMUSG00000004017 +94252 AI256733 MGI:MGI:2137531 +94253 Hecw1 MGI:MGI:2444115|Ensembl:ENSMUSG00000021301 +94254 Rcc1l MGI:MGI:2137600|Ensembl:ENSMUSG00000061979|Vega:OTTMUSG00000024559 +94275 Maged1 MGI:MGI:1930187|Ensembl:ENSMUSG00000025151|Vega:OTTMUSG00000018127 +94279 Sfxn2 MGI:MGI:2137678|Ensembl:ENSMUSG00000025036 +94280 Sfxn3 MGI:MGI:2137679|Ensembl:ENSMUSG00000025212 +94281 Sfxn4 MGI:MGI:2137680|Ensembl:ENSMUSG00000063698|Vega:OTTMUSG00000021213 +94282 Sfxn5 MGI:MGI:2137681|Ensembl:ENSMUSG00000033720|Vega:OTTMUSG00000022777 +94283 Ybx1-ps2 MGI:MGI:2137671 +94284 Ugt1a6a MGI:MGI:2137698|Ensembl:ENSMUSG00000054545|Ensembl:ENSMUSG00000090124|Vega:OTTMUSG00000020818 +94315 Prcc MGI:MGI:2137738|Ensembl:ENSMUSG00000004895|Vega:OTTMUSG00000030643 +94332 Cadm3 MGI:MGI:2137858|Ensembl:ENSMUSG00000005338|Vega:OTTMUSG00000024341 +94346 Tmem40 MGI:MGI:2137870|Ensembl:ENSMUSG00000059900|Vega:OTTMUSG00000024222 +94352 Loxl2 MGI:MGI:2137913|Ensembl:ENSMUSG00000034205|Vega:OTTMUSG00000044487 +94353 Hmgn3 MGI:MGI:2138069|Ensembl:ENSMUSG00000066456|Vega:OTTMUSG00000034786 +96861 C76132 MGI:MGI:2138651 +96867 C77068 MGI:MGI:2138657 +96868 C77183 MGI:MGI:2138658 +96870 C77235 MGI:MGI:2138660 +96872 C77651 MGI:MGI:2138662 +96874 C77874 MGI:MGI:2138664 +96875 Prg4 MGI:MGI:1891344|Ensembl:ENSMUSG00000006014|Vega:OTTMUSG00000033522 +96877 C78142 MGI:MGI:2138667 +96878 C78282 MGI:MGI:2138668 +96882 C78444 MGI:MGI:2138672 +96887 C78997 MGI:MGI:2138677 +96890 C79206 MGI:MGI:2138680 +96891 C79246 MGI:MGI:2138681 +96893 D530037H12Rik MGI:MGI:2138683 +96895 C79946 MGI:MGI:2138685 +96898 C80142 MGI:MGI:2138688 +96899 C80154 MGI:MGI:2138689 +96907 C81001 MGI:MGI:2138697 +96908 C81141 MGI:MGI:2138698 +96909 C81203 MGI:MGI:2138699 +96913 C85133 MGI:MGI:2138703 +96915 C85403 MGI:MGI:2138705 +96922 C86010 MGI:MGI:2138712 +96923 C86103 MGI:MGI:2138713 +96925 C86447 MGI:MGI:2138715 +96926 C86530 MGI:MGI:2138716 +96927 C86562 MGI:MGI:2138717 +96935 Susd4 MGI:MGI:2138351|Ensembl:ENSMUSG00000038576|Vega:OTTMUSG00000027014 +96946 T25612 MGI:MGI:2138736 +96950 C76450 MGI:MGI:2139454 +96951 C76554 MGI:MGI:2139455 +96952 C76662 MGI:MGI:2139456 +96953 C76793 MGI:MGI:2139457 +96955 C77144 MGI:MGI:2139459 +96956 C77267 MGI:MGI:2139460 +96957 Tmem62 MGI:MGI:2139461|Ensembl:ENSMUSG00000054484|Vega:OTTMUSG00000015967 +96960 C77491 MGI:MGI:2139464 +96961 C77609 MGI:MGI:2139465 +96967 C78344 MGI:MGI:2139471 +96971 C78660 MGI:MGI:2139475 +96972 C78760 MGI:MGI:2139476 +96974 C78895 MGI:MGI:2139478 +96978 C79119 MGI:MGI:2139482 +96979 Ptges2 MGI:MGI:1917592|Ensembl:ENSMUSG00000026820|Vega:OTTMUSG00000011987 +96984 C79313 MGI:MGI:2139488 +96987 C79657 MGI:MGI:2139491 +96989 C79685 MGI:MGI:2139493 +96990 C79798 MGI:MGI:2139494 +96993 C80198 MGI:MGI:2139497 +96996 C80276 MGI:MGI:2139500 +96997 C80279 MGI:MGI:2139501 +96999 C80425 MGI:MGI:2139503 +97003 C80719 MGI:MGI:2139507 +97008 C80918 MGI:MGI:2139512 +97010 C81285 MGI:MGI:2139514 +97011 C81302 MGI:MGI:2139515 +97014 C85382 MGI:MGI:2139518 +97017 D2Mgi52 MGI:MGI:2139521 +97024 C87037 MGI:MGI:2139528 +97025 C87129 MGI:MGI:2139529 +97028 C87490 MGI:MGI:2139532 +97031 Tprn MGI:MGI:2139535|Ensembl:ENSMUSG00000048707|Vega:OTTMUSG00000011904 +97047 C76434 MGI:MGI:2140038 +97050 C76838 MGI:MGI:2140041 +97052 C77055 MGI:MGI:2140043 +97053 C77070 MGI:MGI:2140044 +97054 C77135 MGI:MGI:2140045 +97057 C77368 MGI:MGI:2140048 +97064 Wwtr1 MGI:MGI:1917649|Ensembl:ENSMUSG00000027803|Vega:OTTMUSG00000029047 +97065 C78441 MGI:MGI:2140056 +97067 C78651 MGI:MGI:2140058 +97068 C78900 MGI:MGI:2140059 +97071 C79250 MGI:MGI:2140062 +97072 C79256 MGI:MGI:2140063 +97073 C79452 MGI:MGI:2140064 +97074 C79557 MGI:MGI:2140065 +97075 C79743 MGI:MGI:2140066 +97078 C79860 MGI:MGI:2140069 +97086 Slc9b2 MGI:MGI:2140077|Ensembl:ENSMUSG00000037994|Vega:OTTMUSG00000030292 +97089 C80763 MGI:MGI:2140080 +97090 C80914 MGI:MGI:2140081 +97091 C81072 MGI:MGI:2140082 +97095 C81521 MGI:MGI:2140086 +97096 C85129 MGI:MGI:2140087 +97097 C85328 MGI:MGI:2140088 +97101 C85504 MGI:MGI:2140092 +97102 C85600 MGI:MGI:2140093 +97103 C85601 MGI:MGI:2140094 +97104 C85699 MGI:MGI:2140095 +97106 C86098 MGI:MGI:2140097 +97107 C86171 MGI:MGI:2140098 +97112 Nmd3 MGI:MGI:2140103|Ensembl:ENSMUSG00000027787|Vega:OTTMUSG00000029387 +97114 Hist2h3c2 MGI:MGI:2448357|Ensembl:ENSMUSG00000081058|Vega:OTTMUSG00000021934 +97121 T25627 MGI:MGI:2140112 +97122 Hist2h4 MGI:MGI:2140113|Ensembl:ENSMUSG00000091405|Vega:OTTMUSG00000036431 +97124 C76213 MGI:MGI:2140645 +97125 C76555 MGI:MGI:2140646 +97127 C76798 MGI:MGI:2140648 +97128 C76824 MGI:MGI:2140649 +97129 C76876 MGI:MGI:2140650 +97130 C77080 MGI:MGI:2140651|Ensembl:ENSMUSG00000050390|Vega:OTTMUSG00000009618 +97131 C77096 MGI:MGI:2140652 +97134 C77282 MGI:MGI:2140655 +97135 C77396 MGI:MGI:2140656 +97136 C77438 MGI:MGI:2140657 +97137 C77484 MGI:MGI:2140658 +97139 C77664 MGI:MGI:2140660 +97140 C77670 MGI:MGI:2140661 +97142 C77905 MGI:MGI:2140663 +97144 C78128 MGI:MGI:2140665 +97147 C78516 MGI:MGI:2140668 +97148 C78692 MGI:MGI:2140669 +97149 C78893 MGI:MGI:2140670 +97151 C78914 MGI:MGI:2140672 +97153 C79059 MGI:MGI:2140674 +97158 C79562 MGI:MGI:2140679 +97159 A430005L14Rik MGI:MGI:2140680|Ensembl:ENSMUSG00000047613|Vega:OTTMUSG00000010500 +97165 Hmgb2 MGI:MGI:96157|Ensembl:ENSMUSG00000054717|Vega:OTTMUSG00000060717 +97171 C81376 MGI:MGI:2140692 +97177 Gm12670 MGI:MGI:3651682 +97184 C87017 MGI:MGI:2140705 +97187 C87977 MGI:MGI:2140708|Ensembl:ENSMUSG00000046262|Vega:OTTMUSG00000010543 +97188 C88050 MGI:MGI:2140709 +97202 C76614 MGI:MGI:2141273 +97203 C76680 MGI:MGI:2141274 +97204 C76686 MGI:MGI:2141275 +97209 A230098N10Rik MGI:MGI:2141280 +97211 C76992 MGI:MGI:2141282 +97212 Hadha MGI:MGI:2135593|Ensembl:ENSMUSG00000025745|Vega:OTTMUSG00000024740 +97213 C77137 MGI:MGI:2141284 +97214 C77190 MGI:MGI:2141285 +97215 C77266 MGI:MGI:2141286 +97218 C77576 MGI:MGI:2141289 +97221 C77623 MGI:MGI:2141292 +97222 C77691 MGI:MGI:2141293 +97225 C77815 MGI:MGI:2141296 +97227 C77949 MGI:MGI:2141298 +97228 C78157 MGI:MGI:2141299 +97229 C78200 MGI:MGI:2141300 +97230 C78228 MGI:MGI:2141301 +97231 C78278 MGI:MGI:2141302 +97232 C78283 MGI:MGI:2141303 +97234 C78802 MGI:MGI:2141305 +97236 C79130 MGI:MGI:2141307 +97237 C79279 MGI:MGI:2141308 +97238 C79491 MGI:MGI:2141309 +97241 C79870 MGI:MGI:2141312 +97243 Naa11 MGI:MGI:2141314|Ensembl:ENSMUSG00000046000|Vega:OTTMUSG00000053310 +97244 C80140 MGI:MGI:2141315 +97248 C80875 MGI:MGI:2141319 +97249 C80889 MGI:MGI:2141320 +97250 C81026 MGI:MGI:2141321 +97255 C85052 MGI:MGI:2141326 +97257 C85308 MGI:MGI:2141328 +97259 C85922 MGI:MGI:2141330 +97266 C87115 MGI:MGI:2141337 +97268 C230066G23Rik MGI:MGI:2141339 +97279 R74617 MGI:MGI:2141350 +97285 X98549 MGI:MGI:2141356 +97287 Mtmr14 MGI:MGI:1916075|Ensembl:ENSMUSG00000030269|Vega:OTTMUSG00000031092 +97292 C79238 MGI:MGI:2141748 +97294 C79468 MGI:MGI:2141750 +97295 C79476 MGI:MGI:2141751 +97296 C79490 MGI:MGI:2141752 +97298 C79627 MGI:MGI:2141754 +97301 C79744 MGI:MGI:2141757 +97302 C79845 MGI:MGI:2141758 +97307 C80581 MGI:MGI:2141763 +97313 C81537 MGI:MGI:2141769 +97314 C81608 MGI:MGI:2141770 +97327 C87102 MGI:MGI:2141783 +97332 C87482 MGI:MGI:2141788 +97343 T25656 MGI:MGI:2141799 +97349 C76751 MGI:MGI:2142308 +97351 E230006M18Rik MGI:MGI:2142310 +97356 C77495 MGI:MGI:2142315 +97357 C77631 MGI:MGI:2142316 +97358 C77645 MGI:MGI:2142317 +97361 C77717 MGI:MGI:2142320 +97362 C77798 MGI:MGI:2142321 +97369 C78806 MGI:MGI:2142328 +97370 C78948 MGI:MGI:2142329 +97372 C79461 MGI:MGI:2142331 +97373 C79709 MGI:MGI:2142332 +97382 C80256 MGI:MGI:2142341 +97383 C80278 MGI:MGI:2142342 +97385 C80446 MGI:MGI:2142344 +97387 Strn4 MGI:MGI:2142346|Ensembl:ENSMUSG00000030374|Vega:OTTMUSG00000024621 +97389 C80893 MGI:MGI:2142348 +97391 C80915 MGI:MGI:2142350 +97397 C85395 MGI:MGI:2142356 +97400 C85813 MGI:MGI:2142359 +97402 C86187 MGI:MGI:2142361|Ensembl:ENSMUSG00000110001 +97411 6030427F01Rik MGI:MGI:2142370 +97418 Rnu5g MGI:MGI:2157900|Ensembl:ENSMUSG00000095892 +97423 R74862 MGI:MGI:2142382|Ensembl:ENSMUSG00000059277 +97425 R74871 MGI:MGI:2142384 +97431 T25611 MGI:MGI:2142390 +97432 T25625 MGI:MGI:2142391 +97433 T25629 MGI:MGI:2142392 +97434 T25661 MGI:MGI:2142393 +97435 T25670 MGI:MGI:2142394 +97440 B3gnt9 MGI:MGI:2142841|Ensembl:ENSMUSG00000069920|Vega:OTTMUSG00000031384 +97445 C77666 MGI:MGI:2142846 +97448 C78109 MGI:MGI:2142849 +97449 C78280 MGI:MGI:2142850 +97452 C78452 MGI:MGI:2142853 +97455 C78859 MGI:MGI:2142856 +97458 C80012 MGI:MGI:2142859 +97464 C85351 MGI:MGI:2142865 +97476 Fam90a1a MGI:MGI:2142877|Ensembl:ENSMUSG00000079112|Vega:OTTMUSG00000020831 +97477 C87033 MGI:MGI:2142878 +97484 Cog8 MGI:MGI:2142885|Ensembl:ENSMUSG00000031916|Vega:OTTMUSG00000022389 +97485 C88045 MGI:MGI:2142886 +97487 Cmtm4 MGI:MGI:2142888|Ensembl:ENSMUSG00000096188|Vega:OTTMUSG00000061907 +97500 T25669 MGI:MGI:2142901 +97503 W91776 MGI:MGI:2142904 +97507 C76669 MGI:MGI:2143379 +97510 C77010 MGI:MGI:2143382 +97516 C77683 MGI:MGI:2143388 +97517 C77741 MGI:MGI:2143389 +97519 C77901 MGI:MGI:2143391 +97526 C78591 MGI:MGI:2143398 +97530 C79017 MGI:MGI:2143402 +97531 C79240 MGI:MGI:2143403 +97533 C79595 MGI:MGI:2143405 +97536 C79777 MGI:MGI:2143408 +97540 C80258 MGI:MGI:2143412 +97541 Qars MGI:MGI:1915851|Ensembl:ENSMUSG00000032604|Vega:OTTMUSG00000034113 +97543 D9Mgi9 MGI:MGI:2143415 +97544 C81272 MGI:MGI:2143416 +97545 A430027C01Rik MGI:MGI:2143417 +97546 C81436 MGI:MGI:2143418 +97547 C81489 MGI:MGI:2143419 +97548 C81615 MGI:MGI:2143420 +97550 C130081A10Rik MGI:MGI:2143422 +97561 D630038D15Rik MGI:MGI:2143433 +97562 C86345 MGI:MGI:2143434 +97563 C86727 MGI:MGI:2143435 +97564 C86942 MGI:MGI:2143436 +97565 C87018 MGI:MGI:2143437 +97567 C87161 MGI:MGI:2143439 +97569 C87580 MGI:MGI:2143441 +97570 C87679 MGI:MGI:2143442 +97571 C87882 MGI:MGI:2143443 +97576 R75110 MGI:MGI:2143448 +97584 C76537 MGI:MGI:2148045 +97591 C77406 MGI:MGI:2148052 +97592 C77805 MGI:MGI:2148053 +97595 C78297 MGI:MGI:2148056 +97599 C79997 MGI:MGI:2148060 +97600 C80283 MGI:MGI:2148061 +97603 C80406 MGI:MGI:2148064 +97607 C81369 MGI:MGI:2148068 +97608 C81412 MGI:MGI:2148069 +97611 C81461 MGI:MGI:2148072 +97613 C85181 MGI:MGI:2148074 +97614 C85542 MGI:MGI:2148075 +97615 C86371 MGI:MGI:2148076 +97616 C86400 MGI:MGI:2148077 +97618 C87122 MGI:MGI:2148079 +97629 C76711 MGI:MGI:2143910 +97630 C76736 MGI:MGI:2143911 +97637 C78038 MGI:MGI:2143918 +97640 C78653 MGI:MGI:2143921 +97644 C79356 MGI:MGI:2143925 +97649 C79818 MGI:MGI:2143930 +97651 C80360 MGI:MGI:2143932 +97654 C81189 MGI:MGI:2143935 +97655 C81600 MGI:MGI:2143936 +97662 C86090 MGI:MGI:2143943 +97663 C86195 MGI:MGI:2143944 +97664 C86544 MGI:MGI:2143945 +97670 D17892 MGI:MGI:2143951 +97680 T25637 MGI:MGI:2143961 +97683 C76332 MGI:MGI:2144617 +97687 C76628 MGI:MGI:2144621 +97690 C77027 MGI:MGI:2144624 +97691 C77058 MGI:MGI:2144625 +97694 C77583 MGI:MGI:2144628 +97695 C77648 MGI:MGI:2144629 +97696 C77673 MGI:MGI:2144630 +97697 C77714 MGI:MGI:2144631 +97699 C77808 MGI:MGI:2144633 +97703 C78226 MGI:MGI:2144637 +97708 C78568 MGI:MGI:2144642 +97712 C78671 MGI:MGI:2144646 +97713 C78763 MGI:MGI:2144647 +97714 C78891 MGI:MGI:2144648 +97715 C79015 MGI:MGI:2144649 +97719 C79646 MGI:MGI:2144653 +97723 C80060 MGI:MGI:2144657 +97725 C80113 MGI:MGI:2144659 +97726 C80165 MGI:MGI:2144660 +97730 C530030P08Rik MGI:MGI:2144664 +97732 C81184 MGI:MGI:2144666 +97735 C81282 MGI:MGI:2144669 +97736 C81354 MGI:MGI:2144670 +97737 C81435 MGI:MGI:2144671 +97743 C85143 MGI:MGI:2144677 +97752 C86687 MGI:MGI:2144686 +97753 C86807 MGI:MGI:2144687 +97754 C86896 MGI:MGI:2144688 +97756 C87259 MGI:MGI:2144690 +97757 C87286 MGI:MGI:2144691 +97758 C87312 MGI:MGI:2144692 +97761 Sgsm2 MGI:MGI:2144695|Ensembl:ENSMUSG00000038351|Vega:OTTMUSG00000006187 +97775 D930048N14Rik MGI:MGI:2144709|Ensembl:ENSMUSG00000052563|Vega:OTTMUSG00000005607 +97783 C76336 MGI:MGI:2145075 +97784 C76472 MGI:MGI:2145076 +97787 C76872 MGI:MGI:2145079 +97788 C76940 MGI:MGI:2145080 +97789 C77494 MGI:MGI:2145081 +97791 C77734 MGI:MGI:2145083 +97796 C78024 MGI:MGI:2145088 +97798 C78148 MGI:MGI:2145090 +97799 C78242 MGI:MGI:2145091 +97801 C78807 MGI:MGI:2145093 +97805 C79259 MGI:MGI:2145097 +97806 C79296 MGI:MGI:2145098 +97809 C79533 MGI:MGI:2145101 +97810 C80068 MGI:MGI:2145102 +97812 C80120 MGI:MGI:2145104 +97813 C80435 MGI:MGI:2145105 +97814 C80502 MGI:MGI:2145106 +97815 C80571 MGI:MGI:2145107 +97816 C80678 MGI:MGI:2145108 +97817 C80717 MGI:MGI:2145109 +97818 C80831 MGI:MGI:2145110 +97819 C80998 MGI:MGI:2145111 +97820 4833439L19Rik MGI:MGI:1921162|Ensembl:ENSMUSG00000025871|Vega:OTTMUSG00000032658 +97821 E030047P09Rik MGI:MGI:2145113 +97827 Exd2 MGI:MGI:1922485|Ensembl:ENSMUSG00000032705 +97828 C85918 MGI:MGI:2145120 +97831 C86072 MGI:MGI:2145123 +97833 C86753 MGI:MGI:2145125 +97834 C86865 MGI:MGI:2145126 +97836 C87198 MGI:MGI:2145128|Ensembl:ENSMUSG00000092515 +97847 X98554 MGI:MGI:2145139 +97848 Serpinb6c MGI:MGI:2145481|Ensembl:ENSMUSG00000052180|Vega:OTTMUSG00000000721 +97850 C76411 MGI:MGI:2145483 +97851 C130040J23Rik MGI:MGI:2145484 +97852 C76938 MGI:MGI:2145485 +97857 C77563 MGI:MGI:2145490 +97858 C77649 MGI:MGI:2145491 +97859 C77681 MGI:MGI:2145492 +97861 C77788 MGI:MGI:2145494 +97863 Fam8a1 MGI:MGI:2145496|Ensembl:ENSMUSG00000069237|Vega:OTTMUSG00000027736 +97865 C78515 MGI:MGI:2145498 +97866 C78524 MGI:MGI:2145499 +97868 C78704 MGI:MGI:2145501 +97869 C78809 MGI:MGI:2145502 +97870 C78810 MGI:MGI:2145503 +97871 C78878 MGI:MGI:2145504 +97872 C79123 MGI:MGI:2145505 +97874 B430203I24Rik MGI:MGI:2145507 +97875 C79329 MGI:MGI:2145508 +97877 C79741 MGI:MGI:2145510 +97880 C80143 MGI:MGI:2145513 +97881 A530058O07Rik MGI:MGI:2145514 +97884 B3galnt2 MGI:MGI:2145517|Ensembl:ENSMUSG00000039242 +97888 C81086 MGI:MGI:2145521 +97890 C85163 MGI:MGI:2145523 +97895 Nlrp4f MGI:MGI:2145528|Ensembl:ENSMUSG00000032999 +97897 C86273 MGI:MGI:2145530 +97902 Gm11381 MGI:MGI:3650781 +97908 Hist1h3g MGI:MGI:2145541|Ensembl:ENSMUSG00000099517|Vega:OTTMUSG00000000570 +97910 D13Mgi24 MGI:MGI:2145543 +97913 T25641 MGI:MGI:2145546 +97923 C80171 MGI:MGI:2145865 +97928 C85363 MGI:MGI:2145870 +97929 C85539 MGI:MGI:2145871 +97935 C86595 MGI:MGI:2145877 +97936 C87190 MGI:MGI:2145878 +97943 R75382 MGI:MGI:2145885 +97952 C77581 MGI:MGI:2146276 +97954 C77847 MGI:MGI:2146278 +97956 C78115 MGI:MGI:2146280 +97958 C78376 MGI:MGI:2146282 +97959 C78532 MGI:MGI:2146283 +97961 Nol12 MGI:MGI:2146285|Ensembl:ENSMUSG00000033099|Vega:OTTMUSG00000033929 +97962 C78880 MGI:MGI:2146286 +97966 C79122 MGI:MGI:2146290 +97969 C79601 MGI:MGI:2146293 +97976 C81268 MGI:MGI:2146300 +97977 C81508 MGI:MGI:2146301 +97978 C81530 MGI:MGI:2146302 +97983 C85319 MGI:MGI:2146307 +97986 C85445 MGI:MGI:2146310 +97990 C86938 MGI:MGI:2146314 +97998 Deptor MGI:MGI:2146322|Ensembl:ENSMUSG00000022419|Vega:OTTMUSG00000024429 +97999 R75246 MGI:MGI:2146323 +98007 C76493 MGI:MGI:2146695 +98009 C77534 MGI:MGI:2146697 +98010 C77626 MGI:MGI:2146698 +98011 C77872 MGI:MGI:2146699 +98013 C78549 MGI:MGI:2146701 +98019 C79999 MGI:MGI:2146707 +98022 C80993 MGI:MGI:2146710 +98029 C81557 MGI:MGI:2146717 +98034 C86415 MGI:MGI:2146722 +98035 C86498 MGI:MGI:2146723 +98039 C87114 MGI:MGI:2146727 +98046 R74919 MGI:MGI:2146734 +98047 R75537 MGI:MGI:2146735 +98051 C76309 MGI:MGI:2147113 +98053 Gtf2f1 MGI:MGI:1923848|Ensembl:ENSMUSG00000002658 +98059 C77973 MGI:MGI:2147121 +98064 C78888 MGI:MGI:2147126 +98066 C78984 MGI:MGI:2147128 +98068 C79242 MGI:MGI:2147130 +98077 C81431 MGI:MGI:2147139 +98080 B930007P11Rik MGI:MGI:2147142 +98082 C85939 MGI:MGI:2147144 +98087 C87487 MGI:MGI:2147149 +98097 T25614 MGI:MGI:2147159 +98100 C76294 MGI:MGI:2147392 +98103 C76454 MGI:MGI:2147395 +98105 C77097 MGI:MGI:2147397 +98106 C77298 MGI:MGI:2147398 +98108 C77405 MGI:MGI:2147400 +98110 C77591 MGI:MGI:2147402 +98112 C78330 MGI:MGI:2147404 +98115 C79042 MGI:MGI:2147407 +98118 C80865 MGI:MGI:2147410 +98119 C81269 MGI:MGI:2147411 +98120 C81452 MGI:MGI:2147412 +98123 C85771 MGI:MGI:2147415 +98131 R75520 MGI:MGI:2147423 +98134 C76533 MGI:MGI:2147774 +98140 C77545 MGI:MGI:2147780 +98146 C78505 MGI:MGI:2147786 +98149 C79607 MGI:MGI:2147789 +98156 C81363 MGI:MGI:2147796 +98157 C81364 MGI:MGI:2147797 +98158 C81543 MGI:MGI:2147798 +98162 C85546 MGI:MGI:2147802 +98166 C87583 MGI:MGI:2147806 +98170 Tmem132a MGI:MGI:2147810|Ensembl:ENSMUSG00000024736|Vega:OTTMUSG00000028258 +98174 T25620 MGI:MGI:2147814 +98175 W91643 MGI:MGI:2147815 +98176 AA200651 MGI:MGI:2138071 +98193 Dcaf8 MGI:MGI:91860|Ensembl:ENSMUSG00000026554|Vega:OTTMUSG00000050094 +98205 AA516603 MGI:MGI:2138100 +98207 AA517027 MGI:MGI:2138102 +98208 AA517459 MGI:MGI:2138103 +98209 AA517465 MGI:MGI:2138104 +98210 D1Mgi59 MGI:MGI:3722877 +98211 AA517859 MGI:MGI:2138106 +98215 AA536859 MGI:MGI:2138110 +98221 Eif3m MGI:MGI:1351744|Ensembl:ENSMUSG00000027170|Vega:OTTMUSG00000014975 +98224 AA589541 MGI:MGI:2138119 +98231 AA675035 MGI:MGI:2138126 +98238 Lrrc59 MGI:MGI:2138133|Ensembl:ENSMUSG00000020869|Vega:OTTMUSG00000002017 +98247 AA986695 MGI:MGI:2138142 +98250 D1Mgi23 MGI:MGI:2138145 +98254 AI042932 MGI:MGI:2138149 +98256 Kmo MGI:MGI:2138151|Ensembl:ENSMUSG00000039783|Vega:OTTMUSG00000025589 +98258 Txndc9 MGI:MGI:2138153|Ensembl:ENSMUSG00000058407|Vega:OTTMUSG00000026595 +98262 B230337E12Rik MGI:MGI:2138157 +98267 Stk17b MGI:MGI:2138162|Ensembl:ENSMUSG00000026094|Vega:OTTMUSG00000021434 +98285 AI255230 MGI:MGI:2138180 +98299 AI314140 MGI:MGI:2138194 +98303 D630023F18Rik MGI:MGI:2138198|Ensembl:ENSMUSG00000044816|Vega:OTTMUSG00000047693 +98309 AI317187 MGI:MGI:2138204 +98314 D2hgdh MGI:MGI:2138209|Ensembl:ENSMUSG00000073609|Vega:OTTMUSG00000021837 +98319 AI326426 MGI:MGI:2138214 +98363 Efhd1 MGI:MGI:1921607|Ensembl:ENSMUSG00000026255|Vega:OTTMUSG00000029545 +98365 Slamf9 MGI:MGI:1923692|Ensembl:ENSMUSG00000026548|Vega:OTTMUSG00000021429 +98366 Smap1 MGI:MGI:2138261|Ensembl:ENSMUSG00000026155|Vega:OTTMUSG00000026521 +98376 Gorab MGI:MGI:2138271|Ensembl:ENSMUSG00000040124|Vega:OTTMUSG00000049704 +98386 Lbr MGI:MGI:2138281|Ensembl:ENSMUSG00000004880|Vega:OTTMUSG00000050712 +98388 Chst10 MGI:MGI:2138283|Ensembl:ENSMUSG00000026080|Vega:OTTMUSG00000049487 +98396 Slc41a1 MGI:MGI:2444823|Ensembl:ENSMUSG00000013275|Vega:OTTMUSG00000021791 +98397 AI574175 MGI:MGI:2138292 +98401 AI594674 MGI:MGI:2138296 +98402 Sh3bp4 MGI:MGI:2138297|Ensembl:ENSMUSG00000036206|Vega:OTTMUSG00000029359 +98403 Zfp451 MGI:MGI:2137896|Ensembl:ENSMUSG00000042197|Vega:OTTMUSG00000021885 +98404 AI597479 MGI:MGI:2138299|Ensembl:ENSMUSG00000010290|Vega:OTTMUSG00000021985 +98415 Nucks1 MGI:MGI:1934811|Ensembl:ENSMUSG00000026434|Vega:OTTMUSG00000049194 +98417 Cnih4 MGI:MGI:1925828|Ensembl:ENSMUSG00000062169|Vega:OTTMUSG00000022153 +98429 AI834762 MGI:MGI:2138324 +98432 Phlpp1 MGI:MGI:2138327|Ensembl:ENSMUSG00000044340|Vega:OTTMUSG00000021548 +98445 AI844869 MGI:MGI:2138340 +98452 Celrr MGI:MGI:2685664|Ensembl:ENSMUSG00000097881 +98471 AI853363 MGI:MGI:2138366 +98483 D1Mgi53 MGI:MGI:2138378 +98488 Gtf3c3 MGI:MGI:2138383|Ensembl:ENSMUSG00000041303|Vega:OTTMUSG00000046944 +98491 AL022878 MGI:MGI:2138386 +98494 AL024054 MGI:MGI:2138389 +98496 Pid1 MGI:MGI:2138391|Ensembl:ENSMUSG00000045658|Vega:OTTMUSG00000040068 +98498 C130098C10Rik MGI:MGI:2138393 +98506 D1Mgi58 MGI:MGI:2138401 +98511 AU014756 MGI:MGI:2138406 +98514 AU015232 MGI:MGI:2138409 +98528 AU018740 MGI:MGI:2138423 +98531 AU018797 MGI:MGI:2138426 +98541 AU019278 MGI:MGI:2138436 +98558 Mael MGI:MGI:2138453|Ensembl:ENSMUSG00000040629|Vega:OTTMUSG00000026876 +98574 AU022138 MGI:MGI:2138469 +98578 AU022804 MGI:MGI:2138473 +98579 AU022928 MGI:MGI:2138474 +98580 AU023525 MGI:MGI:2138475 +98582 Khdc1b MGI:MGI:2138477|Ensembl:ENSMUSG00000085079|Vega:OTTMUSG00000033753 +98586 AU024699 MGI:MGI:2138481 +98610 AU045220 MGI:MGI:2138505 +98653 AW049021 MGI:MGI:2138548 +98657 AW050000 MGI:MGI:2138552 +98660 Atp1a2 MGI:MGI:88106|Ensembl:ENSMUSG00000007097|Vega:OTTMUSG00000021834 +98661 AW061096 MGI:MGI:2138556 +98662 AW061147 MGI:MGI:2138557 +98682 Mfsd6 MGI:MGI:1922925|Ensembl:ENSMUSG00000041439|Vega:OTTMUSG00000033382 +98685 Trmt1l MGI:MGI:1916185|Ensembl:ENSMUSG00000053286|Vega:OTTMUSG00000049568 +98710 Rabif MGI:MGI:2138605|Ensembl:ENSMUSG00000042229|Vega:OTTMUSG00000049682 +98711 Rdh10 MGI:MGI:1924238|Ensembl:ENSMUSG00000025921|Vega:OTTMUSG00000025248 +98722 AW556253 MGI:MGI:2138617 +98731 AW743052 MGI:MGI:2138626 +98732 Rab3gap2 MGI:MGI:1916043|Ensembl:ENSMUSG00000039318|Vega:OTTMUSG00000050654 +98733 Obsl1 MGI:MGI:2138628|Ensembl:ENSMUSG00000026211|Vega:OTTMUSG00000016912 +98736 1700034H15Rik MGI:MGI:1921515|Ensembl:ENSMUSG00000055833 +98740 BB116930 MGI:MGI:2138635 +98741 Kcnb2 MGI:MGI:99632|Ensembl:ENSMUSG00000092083|Vega:OTTMUSG00000042215 +98743 BB136667 MGI:MGI:2138638 +98744 BB143336 MGI:MGI:2138639 +98748 BB168363 MGI:MGI:2138643 +98750 BB187771 MGI:MGI:2138645 +98752 Fcrla MGI:MGI:2138647|Ensembl:ENSMUSG00000038421|Vega:OTTMUSG00000029894 +98754 A630081D01Rik MGI:MGI:2138649 +98758 Hnrnpf MGI:MGI:2138741|Ensembl:ENSMUSG00000042079|Vega:OTTMUSG00000042359 +98763 AA407782 MGI:MGI:2138746 +98766 Ubac1 MGI:MGI:1920995|Ensembl:ENSMUSG00000036352|Vega:OTTMUSG00000012658 +98778 AA409087 MGI:MGI:2138761 +98783 AA409368 MGI:MGI:2138766 +98787 AA409570 MGI:MGI:2138770 +98795 AA511243 MGI:MGI:2138778 +98796 AA511250 MGI:MGI:2138779 +98797 AA511284 MGI:MGI:2138780 +98798 AA516848 MGI:MGI:2138781 +98799 AA517114 MGI:MGI:2138782 +98800 AA517729 MGI:MGI:2138783 +98801 AA517830 MGI:MGI:2138784 +98809 AA537040 MGI:MGI:2138792 +98813 AA589366 MGI:MGI:2138796 +98819 AA617406 MGI:MGI:2138802 +98823 AA763515 MGI:MGI:2138806 +98825 AA939944 MGI:MGI:2138808 +98828 Cdc123 MGI:MGI:2138811|Ensembl:ENSMUSG00000039128|Vega:OTTMUSG00000010879 +98844 AB039971 MGI:MGI:2138827 +98845 Eps8l2 MGI:MGI:2138828|Ensembl:ENSMUSG00000025504|Vega:OTTMUSG00000024549 +98858 AI131651 MGI:MGI:2138841 +98870 AI182371 MGI:MGI:2138853|Ensembl:ENSMUSG00000035875|Vega:OTTMUSG00000012303 +98871 AI194270 MGI:MGI:2138854 +98878 Ehd4 MGI:MGI:1919619|Ensembl:ENSMUSG00000027293|Vega:OTTMUSG00000015289 +98879 AI197442 MGI:MGI:2138862 +98884 AI225934 MGI:MGI:2138867 +98910 Usp6nl MGI:MGI:2138893|Ensembl:ENSMUSG00000039046|Vega:OTTMUSG00000011789 +98932 Myl9 MGI:MGI:2138915|Ensembl:ENSMUSG00000067818|Vega:OTTMUSG00000016035 +98952 Fam102a MGI:MGI:2138935|Ensembl:ENSMUSG00000039157|Vega:OTTMUSG00000011990 +98956 Nat10 MGI:MGI:2138939|Ensembl:ENSMUSG00000027185|Vega:OTTMUSG00000014874 +98962 AI447567 MGI:MGI:2138945 +98965 AI448005 MGI:MGI:2138948 +98970 Fibcd1 MGI:MGI:2138953|Ensembl:ENSMUSG00000026841|Vega:OTTMUSG00000012076 +98985 Clp1 MGI:MGI:2138968|Ensembl:ENSMUSG00000027079|Vega:OTTMUSG00000013665 +98999 Znfx1 MGI:MGI:2138982|Ensembl:ENSMUSG00000039501|Vega:OTTMUSG00000001138 +99000 AI481121 MGI:MGI:2138983 +99003 Qser1 MGI:MGI:2138986|Ensembl:ENSMUSG00000074994|Vega:OTTMUSG00000014966 +99010 Lpcat4 MGI:MGI:2138993|Ensembl:ENSMUSG00000027134|Vega:OTTMUSG00000015146 +99011 Pomt1 MGI:MGI:2138994|Ensembl:ENSMUSG00000039254|Vega:OTTMUSG00000012947 +99029 AI596198 MGI:MGI:2139012 +99031 Osbpl6 MGI:MGI:2139014|Ensembl:ENSMUSG00000042359|Vega:OTTMUSG00000013133 +99035 Olah MGI:MGI:2139018|Ensembl:ENSMUSG00000026645|Vega:OTTMUSG00000010776 +99041 AI646519 MGI:MGI:2139024 +99045 Mrps26 MGI:MGI:1333830|Ensembl:ENSMUSG00000037740|Vega:OTTMUSG00000015508 +99061 C130057N11Rik MGI:MGI:2139044 +99094 AI849538 MGI:MGI:2139077 +99100 Cep152 MGI:MGI:2139083|Ensembl:ENSMUSG00000068394|Vega:OTTMUSG00000015347 +99104 Gm14290 MGI:MGI:3649702 +99132 AI956758 MGI:MGI:2139115 +99138 Stard7 MGI:MGI:2139090|Ensembl:ENSMUSG00000027367|Vega:OTTMUSG00000016010 +99143 AL022964 MGI:MGI:2139126 +99149 B130033B12Rik MGI:MGI:2139132 +99151 Cercam MGI:MGI:2139134|Ensembl:ENSMUSG00000039787|Vega:OTTMUSG00000012691 +99152 Anapc2 MGI:MGI:2139135|Ensembl:ENSMUSG00000026965|Vega:OTTMUSG00000011902 +99167 Ssx2ip MGI:MGI:2139150|Ensembl:ENSMUSG00000036825|Vega:OTTMUSG00000022292 +99169 AU015228 MGI:MGI:2139152 +99171 AU015584 MGI:MGI:2139154 +99183 AU018505 MGI:MGI:2139166 +99189 AU018693 MGI:MGI:2139172 +99209 AU021128 MGI:MGI:2139192 +99213 AU022092 MGI:MGI:2139196 +99214 AU022121 MGI:MGI:2139197 +99215 AU022255 MGI:MGI:2139198 +99217 AU022695 MGI:MGI:2139200 +99218 AU022702 MGI:MGI:2139201 +99219 AU022840 MGI:MGI:2139202 +99223 AU024573 MGI:MGI:2139206 +99229 AU041474 MGI:MGI:2139212 +99234 AU043555 MGI:MGI:2139217 +99236 AU044856 MGI:MGI:2139219 +99237 Tm9sf4 MGI:MGI:2139220|Ensembl:ENSMUSG00000068040|Vega:OTTMUSG00000015775 +99269 AV099323 MGI:MGI:2139252 +99292 AW047270 MGI:MGI:2139275 +99296 Hrh3 MGI:MGI:2139279|Ensembl:ENSMUSG00000039059|Vega:OTTMUSG00000016256 +99311 Commd7 MGI:MGI:1914197|Ensembl:ENSMUSG00000056941|Vega:OTTMUSG00000016777 +99326 Garnl3 MGI:MGI:2139309|Ensembl:ENSMUSG00000038860|Vega:OTTMUSG00000012572 +99334 Zscan29 MGI:MGI:2139317|Ensembl:ENSMUSG00000050619|Vega:OTTMUSG00000015972 +99349 Dnajc24 MGI:MGI:1919522|Ensembl:ENSMUSG00000027166|Vega:OTTMUSG00000015171 +99371 Arfgef2 MGI:MGI:2139354|Ensembl:ENSMUSG00000074582|Vega:OTTMUSG00000001162 +99375 Cul4a MGI:MGI:1914487|Ensembl:ENSMUSG00000031446|Vega:OTTMUSG00000030982 +99377 Sall4 MGI:MGI:2139360|Ensembl:ENSMUSG00000027547|Vega:OTTMUSG00000016116 +99382 Abtb2 MGI:MGI:2139365|Ensembl:ENSMUSG00000032724|Vega:OTTMUSG00000014876 +99412 Golga2 MGI:MGI:2139395|Ensembl:ENSMUSG00000002546|Vega:OTTMUSG00000012959 +99413 AW555355 MGI:MGI:2139396 +99424 AW742503 MGI:MGI:2139407 +99425 AW742525 MGI:MGI:2139408 +99426 AW742560 MGI:MGI:2139409 +99433 AW822080 MGI:MGI:2139416 +99439 Duox1 MGI:MGI:2139422|Ensembl:ENSMUSG00000033268|Vega:OTTMUSG00000015570 +99440 BB045044 MGI:MGI:2139423 +99444 BB103613 MGI:MGI:2139427 +99458 BB166591 MGI:MGI:2139441 +99459 BB176314 MGI:MGI:2139442 +99462 BB182164 MGI:MGI:2139445 +99463 BB182297 MGI:MGI:2139446 +99467 BB235207 MGI:MGI:2139450 +99468 BB236304 MGI:MGI:2139451 +99470 Magi3 MGI:MGI:1923484|Ensembl:ENSMUSG00000052539|Vega:OTTMUSG00000028459 +99480 Dnttip2 MGI:MGI:1923173|Ensembl:ENSMUSG00000039756|Vega:OTTMUSG00000052420 +99485 AA409016 MGI:MGI:2139566 +99499 AA511261 MGI:MGI:2139580 +99500 AA511275 MGI:MGI:2139581 +99501 AA516838 MGI:MGI:2139582 +99502 AA516946 MGI:MGI:2139583 +99503 AA517023 MGI:MGI:2139584 +99505 AA517742 MGI:MGI:2139586 +99506 AA517765 MGI:MGI:2139587 +99507 AA522016 MGI:MGI:2139588 +99510 AA545176 MGI:MGI:2139591 +99512 Wdr47 MGI:MGI:2139593|Ensembl:ENSMUSG00000040389|Vega:OTTMUSG00000007257 +99516 AA589439 MGI:MGI:2139597 +99517 AA589455 MGI:MGI:2139598 +99518 AA589472 MGI:MGI:2139599 +99520 AA589608 MGI:MGI:2139601 +99522 AA672641 MGI:MGI:2139603 +99526 Usp53 MGI:MGI:2139607|Ensembl:ENSMUSG00000039701|Vega:OTTMUSG00000052461 +99542 AI115009 MGI:MGI:2139623|Ensembl:ENSMUSG00000097745 +99543 Olfml3 MGI:MGI:1914877|Ensembl:ENSMUSG00000027848|Vega:OTTMUSG00000046189 +99561 AI181833 MGI:MGI:2139642 +99571 Fgg MGI:MGI:95526|Ensembl:ENSMUSG00000033860|Vega:OTTMUSG00000051802 +99572 AI256698 MGI:MGI:2139653 +99586 Dpyd MGI:MGI:2139667|Ensembl:ENSMUSG00000033308|Vega:OTTMUSG00000025956 +99627 AI447881 MGI:MGI:2139708 +99633 Adgrl2 MGI:MGI:2139714|Ensembl:ENSMUSG00000028184|Vega:OTTMUSG00000055224 +99650 4933434E20Rik MGI:MGI:1914027|Ensembl:ENSMUSG00000027942|Vega:OTTMUSG00000034166 +99662 Eps8l3 MGI:MGI:2139743|Ensembl:ENSMUSG00000040600|Vega:OTTMUSG00000053020 +99663 Clca4a MGI:MGI:2139744|Ensembl:ENSMUSG00000068547|Vega:OTTMUSG00000031904 +99679 AI595385 MGI:MGI:2139760 +99681 Tchh MGI:MGI:2177944|Ensembl:ENSMUSG00000052415|Vega:OTTMUSG00000051989 +99683 Sec24b MGI:MGI:2139764|Ensembl:ENSMUSG00000001052|Vega:OTTMUSG00000036442 +99686 AI606473 MGI:MGI:2139767|Ensembl:ENSMUSG00000093738 +99696 Ankrd50 MGI:MGI:2139777|Ensembl:ENSMUSG00000044864|Vega:OTTMUSG00000026512 +99702 AI663974 MGI:MGI:2139783 +99709 Clca4b MGI:MGI:2139790|Ensembl:ENSMUSG00000074195|Vega:OTTMUSG00000033449 +99712 Cept1 MGI:MGI:2139793|Ensembl:ENSMUSG00000040774|Vega:OTTMUSG00000029486 +99730 Taf13 MGI:MGI:1913500|Ensembl:ENSMUSG00000048100|Vega:OTTMUSG00000007260 +99738 Kcnc4 MGI:MGI:96670|Ensembl:ENSMUSG00000027895|Vega:OTTMUSG00000052959 +99757 AI854905 MGI:MGI:2139838 +99774 AL023079 MGI:MGI:2139855 +99779 AU015247 MGI:MGI:2139860 +99797 AU019157 MGI:MGI:2139878 +99801 AU021001 MGI:MGI:2139882 +99805 AU021871 MGI:MGI:2139886 +99811 AU022297 MGI:MGI:2139892 +99812 AU022320 MGI:MGI:2139893 +99813 AU022332 MGI:MGI:2139894 +99814 AU022436 MGI:MGI:2139895 +99815 AU022733 MGI:MGI:2139896 +99817 AU022881 MGI:MGI:2139898 +99820 AU024605 MGI:MGI:2139901 +99823 AU040958 MGI:MGI:2139904 +99839 AU067648 MGI:MGI:2139920 +99870 AW047730 MGI:MGI:2139951 +99887 Tmem56 MGI:MGI:1923195|Ensembl:ENSMUSG00000028132|Vega:OTTMUSG00000032849 +99889 Arfip1 MGI:MGI:1277120|Ensembl:ENSMUSG00000074513|Ensembl:ENSMUSG00000102805|Vega:OTTMUSG00000032734|Vega:OTTMUSG00000051615 +99890 Prmt6 MGI:MGI:2139971|Ensembl:ENSMUSG00000049300|Vega:OTTMUSG00000020268 +99896 AW209116 MGI:MGI:2139977 +99899 Ifi44 MGI:MGI:2443016|Ensembl:ENSMUSG00000028037|Vega:OTTMUSG00000022663 +99922 AW552393 MGI:MGI:2140003 +99929 Tiparp MGI:MGI:2159210|Ensembl:ENSMUSG00000034640|Vega:OTTMUSG00000022169 +99934 AW743297 MGI:MGI:2140015 +99935 BB018844 MGI:MGI:2140016 +99939 BB085087 MGI:MGI:2140020 +99944 BB131052 MGI:MGI:2140025 +99946 6720422M22Rik MGI:MGI:2140027 +99947 BB145683 MGI:MGI:2140028 +99952 BB187690 MGI:MGI:2140033 +99958 AA407111 MGI:MGI:2140116 +99977 AA408705 MGI:MGI:2140135 +99982 Kdm1a MGI:MGI:1196256|Ensembl:ENSMUSG00000036940|Vega:OTTMUSG00000009707 +99996 AA416453 MGI:MGI:2140154 +100010 AA589556 MGI:MGI:2140168 +100012 Oog3 MGI:MGI:2684047|Ensembl:ENSMUSG00000050810|Vega:OTTMUSG00000010434 +100014 AA673240 MGI:MGI:2140172 +100017 Ldlrap1 MGI:MGI:2140175|Ensembl:ENSMUSG00000037295|Vega:OTTMUSG00000011121 +100019 Mdn1 MGI:MGI:1926159|Ensembl:ENSMUSG00000058006|Vega:OTTMUSG00000004945 +100032 AI115522 MGI:MGI:2140190 +100034 AI115610 MGI:MGI:2140192 +100050 AI197429 MGI:MGI:2140208 +100051 AI225779 MGI:MGI:2140209 +100061 Lrrc19 MGI:MGI:2140219|Ensembl:ENSMUSG00000049799|Vega:OTTMUSG00000007857 +100066 Cyp2j11 MGI:MGI:2140224|Ensembl:ENSMUSG00000066097|Vega:OTTMUSG00000007865 +100071 AI316872 MGI:MGI:2140229 +100072 Camta1 MGI:MGI:2140230|Ensembl:ENSMUSG00000014592|Vega:OTTMUSG00000010309 +100087 Kti12 MGI:MGI:1923547|Ensembl:ENSMUSG00000073775|Vega:OTTMUSG00000008233 +100088 Rcc1 MGI:MGI:1913989|Ensembl:ENSMUSG00000028896|Vega:OTTMUSG00000009575 +100090 Zbtb48 MGI:MGI:2140248|Ensembl:ENSMUSG00000028952|Vega:OTTMUSG00000010373 +100102 Pcsk9 MGI:MGI:2140260|Ensembl:ENSMUSG00000044254|Vega:OTTMUSG00000008197 +100109 AI427012 MGI:MGI:2140267 +100115 AI428898 MGI:MGI:2140273 +100121 Tdrd7 MGI:MGI:2140279|Ensembl:ENSMUSG00000035517|Vega:OTTMUSG00000006834 +100124 AI448984 MGI:MGI:2140282 +100129 Gpr153 MGI:MGI:1916157|Ensembl:ENSMUSG00000042804|Vega:OTTMUSG00000010405 +100145 AI467481 MGI:MGI:2140303 +100155 AI481877 MGI:MGI:2140313|Ensembl:ENSMUSG00000038598|Vega:OTTMUSG00000007630 +100163 Pafah2 MGI:MGI:2140321|Ensembl:ENSMUSG00000037366|Vega:OTTMUSG00000010831 +100165 AI507597 MGI:MGI:2140323|Ensembl:ENSMUSG00000073731 +100169 Phactr4 MGI:MGI:2140327|Ensembl:ENSMUSG00000066043|Vega:OTTMUSG00000009635 +100177 Zmym6 MGI:MGI:106505|Ensembl:ENSMUSG00000042408|Vega:OTTMUSG00000009333 +100182 Akna MGI:MGI:2140340|Ensembl:ENSMUSG00000039158|Vega:OTTMUSG00000014249 +100194 AI666798 MGI:MGI:2140352 +100198 H6pd MGI:MGI:2140356|Ensembl:ENSMUSG00000028980|Vega:OTTMUSG00000010275 +100201 Tmem64 MGI:MGI:2140359|Ensembl:ENSMUSG00000043252|Vega:OTTMUSG00000004587 +100206 Adprhl2 MGI:MGI:2140364|Ensembl:ENSMUSG00000042558|Vega:OTTMUSG00000009358 +100210 Gpn2 MGI:MGI:2140368|Ensembl:ENSMUSG00000028848|Vega:OTTMUSG00000011156 +100213 Rusc2 MGI:MGI:2140371|Ensembl:ENSMUSG00000035969|Vega:OTTMUSG00000006785 +100223 9630041G16Rik MGI:MGI:2140381 +100226 Stx12 MGI:MGI:1931027|Ensembl:ENSMUSG00000028879|Vega:OTTMUSG00000010095 +100252 AL022876 MGI:MGI:2140410 +100266 AU015084 MGI:MGI:2140424 +100268 AU015268 MGI:MGI:2140426 +100270 AU015581 MGI:MGI:2140428 +100272 AU015623 MGI:MGI:2140430 +100273 Osbpl9 MGI:MGI:1923784|Ensembl:ENSMUSG00000028559|Vega:OTTMUSG00000008293 +100274 AU015892 MGI:MGI:2140432 +100278 AU018039 MGI:MGI:2140436 +100279 AU018381 MGI:MGI:2140437 +100287 AU019176 MGI:MGI:2140445 +100309 AU022479 MGI:MGI:2140467 +100310 LOC100310 - +100311 AU022680 MGI:MGI:2140469 +100313 AU022899 MGI:MGI:2140471 +100317 AU040320 MGI:MGI:2140475|Ensembl:ENSMUSG00000028830|Vega:OTTMUSG00000009282 +100329 AU043392 MGI:MGI:2140487 +100334 AU044157 MGI:MGI:2140492 +100336 Ppp1r8 MGI:MGI:2140494|Ensembl:ENSMUSG00000028882|Vega:OTTMUSG00000009995 +100340 Smpdl3b MGI:MGI:1916022|Ensembl:ENSMUSG00000028885|Vega:OTTMUSG00000009962 +100342 Fam46b MGI:MGI:2140500|Ensembl:ENSMUSG00000046694|Vega:OTTMUSG00000011145 +100346 AU067697 MGI:MGI:2140504 +100382 AW011738 MGI:MGI:2140540 +100383 Bsdc1 MGI:MGI:1913466|Ensembl:ENSMUSG00000040859|Vega:OTTMUSG00000009659 +100434 Slc44a1 MGI:MGI:2140592|Ensembl:ENSMUSG00000028412|Vega:OTTMUSG00000007068 +100455 AW743053 MGI:MGI:2140613 +100456 AW743107 MGI:MGI:2140614 +100458 AW743250 MGI:MGI:2140616 +100459 AW743301 MGI:MGI:2140617 +100461 AW743345 MGI:MGI:2140619 +100462 AW743448 MGI:MGI:2140620 +100465 Mob3c MGI:MGI:2140623|Ensembl:ENSMUSG00000028709|Vega:OTTMUSG00000008686 +100467 AW987390 MGI:MGI:2140625 +100470 Lao1 MGI:MGI:2140628|Ensembl:ENSMUSG00000024903|Vega:OTTMUSG00000008819 +100473 BB031773 MGI:MGI:2140631|Ensembl:ENSMUSG00000085041 +100479 BB131254 MGI:MGI:2140637 +100483 BB168181 MGI:MGI:2140641 +100485 BB214985 MGI:MGI:2140643 +100494 Zfand2a MGI:MGI:2140729|Ensembl:ENSMUSG00000053581|Vega:OTTMUSG00000023062 +100498 AA408213 MGI:MGI:2140733 +100509 AA409244 MGI:MGI:2140744 +100515 Zfp518b MGI:MGI:2140750|Ensembl:ENSMUSG00000046572|Vega:OTTMUSG00000042276 +100518 AA516635 MGI:MGI:2140753 +100519 AA516738 MGI:MGI:2140754 +100522 AA516935 MGI:MGI:2140757 +100523 AA516953 MGI:MGI:2140758 +100524 AA516956 MGI:MGI:2140759 +100525 AA517122 MGI:MGI:2140760 +100526 AA517457 MGI:MGI:2140761 +100527 AA517641 MGI:MGI:2140762 +100528 AA517832 MGI:MGI:2140763 +100529 AA517864 MGI:MGI:2140764 +100530 AA522022 MGI:MGI:2140765 +100532 Rell1 MGI:MGI:2140767|Ensembl:ENSMUSG00000047881|Vega:OTTMUSG00000055342 +100533 AA536748 MGI:MGI:2140768 +100535 Oas1d MGI:MGI:2140770|Ensembl:ENSMUSG00000032623|Vega:OTTMUSG00000025364 +100539 AA571391 MGI:MGI:2140774 +100540 AA589385 MGI:MGI:2140775 +100541 AA589521 MGI:MGI:2140776 +100542 AA589577 MGI:MGI:2140777 +100545 AA617259 MGI:MGI:2140780 +100548 D130004A15Rik MGI:MGI:2140783 +100552 AA675344 MGI:MGI:2140787 +100554 AA792892 MGI:MGI:2140789|Ensembl:ENSMUSG00000073497|Vega:OTTMUSG00000055646 +100559 Ugt2b38 MGI:MGI:2140794|Ensembl:ENSMUSG00000061906|Vega:OTTMUSG00000026794 +100561 Slc15a4 MGI:MGI:2140796|Ensembl:ENSMUSG00000029416|Vega:OTTMUSG00000028813 +100562 AB039976 MGI:MGI:2140797 +100571 AI115602 MGI:MGI:2140806 +100578 AI181832 MGI:MGI:2140813 +100604 Lrrc8c MGI:MGI:2140839|Ensembl:ENSMUSG00000054720|Vega:OTTMUSG00000026735 +100608 Noc4l MGI:MGI:2140843|Ensembl:ENSMUSG00000033294|Vega:OTTMUSG00000026236 +100609 Nsun5 MGI:MGI:2140844|Ensembl:ENSMUSG00000000916|Vega:OTTMUSG00000024361 +100620 AI413194 MGI:MGI:2140855 +100637 N4bp2l1 MGI:MGI:2140872|Ensembl:ENSMUSG00000041132|Vega:OTTMUSG00000055535 +100640 AI429363 MGI:MGI:2140875 +100647 Upk3b MGI:MGI:2140882|Ensembl:ENSMUSG00000042985|Vega:OTTMUSG00000021768 +100653 AI449212 MGI:MGI:2140888 +100662 D930016D06Rik MGI:MGI:2442700|Ensembl:ENSMUSG00000097392 +100669 9930105H17Rik MGI:MGI:2140904 +100675 AI480526 MGI:MGI:2140910 +100678 Psph MGI:MGI:97788|Ensembl:ENSMUSG00000029446|Vega:OTTMUSG00000027654 +100683 Trrap MGI:MGI:2153272|Ensembl:ENSMUSG00000045482|Vega:OTTMUSG00000017164 +100689 Spon2 MGI:MGI:1923724|Ensembl:ENSMUSG00000037379|Vega:OTTMUSG00000055359 +100698 AI562086 MGI:MGI:2140933 +100702 Gbp6 MGI:MGI:2140937|Ensembl:ENSMUSG00000079362|Ensembl:ENSMUSG00000104713|Vega:OTTMUSG00000053861|Vega:OTTMUSG00000053879 +100705 Acacb MGI:MGI:2140940|Ensembl:ENSMUSG00000042010|Vega:OTTMUSG00000014407 +100710 Pds5b MGI:MGI:2140945|Ensembl:ENSMUSG00000034021|Vega:OTTMUSG00000017116 +100715 Papd4 MGI:MGI:2140950|Ensembl:ENSMUSG00000042167 +100727 Ugt2b34 MGI:MGI:2140962|Ensembl:ENSMUSG00000029260|Vega:OTTMUSG00000022931 +100732 Mapre3 MGI:MGI:2140967|Ensembl:ENSMUSG00000029166|Vega:OTTMUSG00000022303 +100737 Dcun1d4 MGI:MGI:2140972|Ensembl:ENSMUSG00000051674|Vega:OTTMUSG00000024911 +100740 AI839979 MGI:MGI:2140975 +100756 Usp30 MGI:MGI:2140991|Ensembl:ENSMUSG00000029592|Vega:OTTMUSG00000016815 +100763 Ube3c MGI:MGI:2140998|Ensembl:ENSMUSG00000039000|Vega:OTTMUSG00000054280 +100764 Rita1 MGI:MGI:1922021|Ensembl:ENSMUSG00000029600|Vega:OTTMUSG00000025342 +100782 AL023051 MGI:MGI:2141017 +100791 AU014888 MGI:MGI:2141026 +100793 AU015619 MGI:MGI:2141028 +100798 AU017193 MGI:MGI:2141033 +100801 AU018552 MGI:MGI:2141036 +100809 AU018966 MGI:MGI:2141044 +100822 AU021755 MGI:MGI:2141057 +100825 AU022245 MGI:MGI:2141060 +100827 AU022322 MGI:MGI:2141062 +100830 AU022526 MGI:MGI:2141065 +100831 AU022531 MGI:MGI:2141066 +100832 AU022537 MGI:MGI:2141067 +100837 AU023639 MGI:MGI:2141072 +100839 AU024546 MGI:MGI:2141074 +100855 Tbc1d14 MGI:MGI:1098708|Ensembl:ENSMUSG00000029192|Vega:OTTMUSG00000033875 +100877 AV074028 MGI:MGI:2141112 +100885 AV276577 MGI:MGI:2141120 +100900 Hscb MGI:MGI:2141135|Ensembl:ENSMUSG00000043510|Vega:OTTMUSG00000028663 +100904 AW050077 MGI:MGI:2141139 +100910 Chpf2 MGI:MGI:1917522|Ensembl:ENSMUSG00000038181|Vega:OTTMUSG00000030540 +100929 Tyw1 MGI:MGI:2141161|Ensembl:ENSMUSG00000056310|Vega:OTTMUSG00000027917 +100931 AW125646 MGI:MGI:2141163 +100952 Emilin1 MGI:MGI:1926189|Ensembl:ENSMUSG00000029163|Vega:OTTMUSG00000035952 +100972 Rab28 MGI:MGI:1917285|Ensembl:ENSMUSG00000029128|Vega:OTTMUSG00000055786 +100977 D5Mgi13 MGI:MGI:2141209 +100978 Nfxl1 MGI:MGI:1923646|Ensembl:ENSMUSG00000072889|Vega:OTTMUSG00000026056 +100986 Akap9 MGI:MGI:2178217|Ensembl:ENSMUSG00000040407|Vega:OTTMUSG00000016263 +100993 AW549542 MGI:MGI:2141225|Ensembl:ENSMUSG00000087516 +101010 AW742247 MGI:MGI:2141242 +101017 AW822016 MGI:MGI:2141249 +101020 AW985879 MGI:MGI:2141252 +101023 Zfp513 MGI:MGI:2141255|Ensembl:ENSMUSG00000043059|Vega:OTTMUSG00000022493 +101024 BB013350 MGI:MGI:2141256 +101028 BB070754 MGI:MGI:2141260 +101033 BB136935 MGI:MGI:2141265 +101036 BB155983 MGI:MGI:2141268 +101048 AA517576 MGI:MGI:2141366 +101052 AA589573 MGI:MGI:2141370 +101057 AB059417 MGI:MGI:2141375 +101060 AI118068 MGI:MGI:2141378 +101071 AI315681 MGI:MGI:2141389 +101095 Zfp282 MGI:MGI:2141413|Ensembl:ENSMUSG00000025821|Vega:OTTMUSG00000022846 +101100 Ttll3 MGI:MGI:2141418|Ensembl:ENSMUSG00000030276|Vega:OTTMUSG00000017554 +101101 AI451035 MGI:MGI:2141419 +101113 Snx21 MGI:MGI:1917729|Ensembl:ENSMUSG00000050373|Vega:OTTMUSG00000001102 +101118 Tmem168 MGI:MGI:1921794|Ensembl:ENSMUSG00000029569|Vega:OTTMUSG00000023860 +101120 AI506767 MGI:MGI:2141438 +101122 Rpusd3 MGI:MGI:2141440|Ensembl:ENSMUSG00000051169|Vega:OTTMUSG00000024195 +101123 D6Mgi31 MGI:MGI:2141441 +101142 Itfg2 MGI:MGI:1915450|Ensembl:ENSMUSG00000001518|Vega:OTTMUSG00000023984 +101148 Bmt2 MGI:MGI:2141466|Ensembl:ENSMUSG00000042742|Vega:OTTMUSG00000057089 +101179 6430519N07Rik MGI:MGI:2141497 +101185 Pot1a MGI:MGI:2141503|Ensembl:ENSMUSG00000029676|Vega:OTTMUSG00000023472 +101187 Parp11 MGI:MGI:2141505|Ensembl:ENSMUSG00000037997|Vega:OTTMUSG00000023340 +101190 AI853106 MGI:MGI:2141508 +101197 Zfp956 MGI:MGI:2141515|Ensembl:ENSMUSG00000045466|Vega:OTTMUSG00000028883 +101202 Hepacam2 MGI:MGI:2141520|Ensembl:ENSMUSG00000044156|Vega:OTTMUSG00000042625 +101206 Tada3 MGI:MGI:1915724|Ensembl:ENSMUSG00000048930|Vega:OTTMUSG00000023740 +101214 Tra2a MGI:MGI:1933972|Ensembl:ENSMUSG00000029817|Vega:OTTMUSG00000057408 +101228 AU014678 MGI:MGI:2141546 +101232 AU015536 MGI:MGI:2141550 +101236 AU016938 MGI:MGI:2141554 +101240 Wdr91 MGI:MGI:2141558|Ensembl:ENSMUSG00000058486|Vega:OTTMUSG00000022802 +101249 AU021805 MGI:MGI:2141567 +101250 AU022084 MGI:MGI:2141568 +101251 AU022166 MGI:MGI:2141569 +101254 AU022697 MGI:MGI:2141572 +101255 AU022706 MGI:MGI:2141573 +101261 AU024342 MGI:MGI:2141579 +101264 D6Mgi33 MGI:MGI:2141582 +101267 AU041156 MGI:MGI:2141585 +101272 AU043415 MGI:MGI:2141590 +101280 AU046084 MGI:MGI:2141598 +101286 AU020745 MGI:MGI:2141604 +101314 Brk1 MGI:MGI:1915406|Ensembl:ENSMUSG00000033940|Vega:OTTMUSG00000056403 +101320 Dyrk4 MGI:MGI:1330292|Ensembl:ENSMUSG00000030345|Vega:OTTMUSG00000023498 +101351 Eogt MGI:MGI:2141669|Ensembl:ENSMUSG00000035245|Vega:OTTMUSG00000023403 +101358 Fbxl14 MGI:MGI:2141676|Ensembl:ENSMUSG00000030019|Vega:OTTMUSG00000024104 +101359 Prrt4 MGI:MGI:2141677|Ensembl:ENSMUSG00000079654|Vega:OTTMUSG00000034247 +101365 AW493563 MGI:MGI:2141683 +101399 AW742329 MGI:MGI:2141717 +101400 AW742418 MGI:MGI:2141718 +101401 Adamts9 MGI:MGI:1916320|Ensembl:ENSMUSG00000030022|Vega:OTTMUSG00000025821 +101402 AW743318 MGI:MGI:2141720 +101403 AW987477 MGI:MGI:2141721 +101406 6030456E01Rik MGI:MGI:2141724 +101420 BB178967 MGI:MGI:2141738 +101434 Ceacam15 MGI:MGI:2141810|Ensembl:ENSMUSG00000078795|Vega:OTTMUSG00000058774 +101437 Dhx32 MGI:MGI:2141813|Ensembl:ENSMUSG00000030986|Vega:OTTMUSG00000022581 +101438 AA408156 MGI:MGI:2141814 +101447 AA409587 MGI:MGI:2141823 +101452 AA415014 MGI:MGI:2141828 +101454 AA516940 MGI:MGI:2141830 +101455 AA517479 MGI:MGI:2141831 +101456 AA517545 MGI:MGI:2141832 +101458 AA536887 MGI:MGI:2141834 +101460 AA536965 MGI:MGI:2141836 +101462 AA537064 MGI:MGI:2141838 +101471 Phrf1 MGI:MGI:2141847|Ensembl:ENSMUSG00000038611|Vega:OTTMUSG00000024537 +101476 Plekha1 MGI:MGI:2442213|Ensembl:ENSMUSG00000040268|Vega:OTTMUSG00000029137 +101477 AA960618 MGI:MGI:2141853 +101488 Slco2b1 MGI:MGI:1351872|Ensembl:ENSMUSG00000030737|Vega:OTTMUSG00000024669 +101489 Ric8a MGI:MGI:2141866|Ensembl:ENSMUSG00000025485|Vega:OTTMUSG00000023444 +101490 Inpp5f MGI:MGI:2141867|Ensembl:ENSMUSG00000042105|Vega:OTTMUSG00000029375 +101494 AI132709 MGI:MGI:2141871 +101497 Plekhg2 MGI:MGI:2141874|Ensembl:ENSMUSG00000037552|Vega:OTTMUSG00000031950 +101498 AI194348 MGI:MGI:2141875 +101502 Hsd3b7 MGI:MGI:2141879|Ensembl:ENSMUSG00000042289|Vega:OTTMUSG00000058631 +101508 AI255212 MGI:MGI:2141885 +101513 Mob2 MGI:MGI:1919891|Ensembl:ENSMUSG00000025147|Vega:OTTMUSG00000060197 +101514 AI256670 MGI:MGI:2141891 +101521 AI314278 MGI:MGI:2141898|Ensembl:ENSMUSG00000109311 +101522 AI314338 MGI:MGI:2141899 +101533 Klk9 MGI:MGI:1921082|Ensembl:ENSMUSG00000047884|Vega:OTTMUSG00000058310 +101540 Prkd2 MGI:MGI:2141917|Ensembl:ENSMUSG00000041187|Vega:OTTMUSG00000058118 +101543 Wtip MGI:MGI:2141920|Ensembl:ENSMUSG00000036459|Vega:OTTMUSG00000008381 +101544 Zfp575 MGI:MGI:2141921|Ensembl:ENSMUSG00000066721|Vega:OTTMUSG00000058222 +101557 AI415467 MGI:MGI:2141934 +101563 AI426330 MGI:MGI:2141940 +101565 Ccp110 MGI:MGI:2141942|Ensembl:ENSMUSG00000033904|Vega:OTTMUSG00000026093 +101568 Vrk3 MGI:MGI:2182465|Ensembl:ENSMUSG00000002205|Vega:OTTMUSG00000022259 +101592 Efl1 MGI:MGI:2141969|Ensembl:ENSMUSG00000038563|Vega:OTTMUSG00000027342 +101602 AI467606 MGI:MGI:2141979|Ensembl:ENSMUSG00000045165|Vega:OTTMUSG00000058495 +101604 E430018J23Rik MGI:MGI:2141981|Ensembl:ENSMUSG00000078580|Vega:OTTMUSG00000035264 +101612 Grwd1 MGI:MGI:2141989|Ensembl:ENSMUSG00000053801|Vega:OTTMUSG00000033591 +101613 Nlrp6 MGI:MGI:2141990|Ensembl:ENSMUSG00000038745|Vega:OTTMUSG00000044619 +101631 Pwwp2b MGI:MGI:2142008|Ensembl:ENSMUSG00000060260|Vega:OTTMUSG00000060494 +101637 AI616248 MGI:MGI:2142014 +101646 B830008H07Rik MGI:MGI:2142023 +101651 AI785031 MGI:MGI:2142028 +101685 Spty2d1 MGI:MGI:2142062|Ensembl:ENSMUSG00000049516|Vega:OTTMUSG00000027277 +101693 AI854308 MGI:MGI:2142070 +101694 Mir9-3hg MGI:MGI:2142071|Ensembl:ENSMUSG00000097023 +101700 Trim68 MGI:MGI:2142077|Ensembl:ENSMUSG00000073968|Vega:OTTMUSG00000060499 +101706 Numa1 MGI:MGI:2443665|Ensembl:ENSMUSG00000066306|Vega:OTTMUSG00000035829 +101715 AL023008 MGI:MGI:2142092 +101719 AL024128 MGI:MGI:2142096 +101735 AU015105 MGI:MGI:2142112 +101736 AU015263 MGI:MGI:2142113 +101738 AU015558 MGI:MGI:2142115 +101739 Psip1 MGI:MGI:2142116|Ensembl:ENSMUSG00000028484|Vega:OTTMUSG00000000034 +101744 Acp7 MGI:MGI:2142121|Ensembl:ENSMUSG00000037469|Vega:OTTMUSG00000029065 +101749 AU018832 MGI:MGI:2142126 +101756 AU019752 MGI:MGI:2142133 +101759 AU021169 MGI:MGI:2142136 +101764 AU022374 MGI:MGI:2142141 +101769 AU023617 MGI:MGI:2142146 +101772 Ano1 MGI:MGI:2142149|Ensembl:ENSMUSG00000031075|Vega:OTTMUSG00000030429 +101786 A730082K24Rik MGI:MGI:2142163|Ensembl:ENSMUSG00000108379 +101804 AV258160 MGI:MGI:2142181 +101807 AV356131 MGI:MGI:2142184 +101809 Spred3 MGI:MGI:2142186|Ensembl:ENSMUSG00000037239|Vega:OTTMUSG00000023179 +101821 AW050198 MGI:MGI:2142198 +101831 Faap24 MGI:MGI:2142208|Ensembl:ENSMUSG00000030493|Vega:OTTMUSG00000024888 +101835 AW146154 MGI:MGI:2142212|Ensembl:ENSMUSG00000074166|Vega:OTTMUSG00000037961 +101856 AW488515 MGI:MGI:2142233 +101861 Ints4 MGI:MGI:1917164|Ensembl:ENSMUSG00000025133|Vega:OTTMUSG00000058266 +101867 Rrp8 MGI:MGI:1914251|Ensembl:ENSMUSG00000030888|Vega:OTTMUSG00000025597 +101869 Unc45a MGI:MGI:2142246|Ensembl:ENSMUSG00000030533|Vega:OTTMUSG00000024949 +101883 Igflr1 MGI:MGI:3655979|Ensembl:ENSMUSG00000036826|Vega:OTTMUSG00000036724 +101894 AW742548 MGI:MGI:2142271 +101896 AW743092 MGI:MGI:2142273 +101918 BB144871 MGI:MGI:2142295 +101920 BB155753 MGI:MGI:2142297 +101923 BB212172 MGI:MGI:2142300 +101926 AA407107 MGI:MGI:2142395 +101931 AA407881 MGI:MGI:2142400 +101936 AA408456 MGI:MGI:2142405 +101942 AA409261 MGI:MGI:2142411 +101943 Sf3b3 MGI:MGI:1289341|Ensembl:ENSMUSG00000033732|Vega:OTTMUSG00000061894 +101955 AA516637 MGI:MGI:2142424 +101956 AA516945 MGI:MGI:2142425 +101957 AA517631 MGI:MGI:2142426 +101961 AA589427 MGI:MGI:2142430 +101963 AA589503 MGI:MGI:2142432 +101966 D8Ertd738e MGI:MGI:1289231|Ensembl:ENSMUSG00000019362|Vega:OTTMUSG00000061279 +101967 AA591044 MGI:MGI:2142436 +101969 AA672651 MGI:MGI:2142438 +101973 AA682107 MGI:MGI:2142442 +101985 Usb1 MGI:MGI:2142454|Ensembl:ENSMUSG00000031792|Vega:OTTMUSG00000031300 +101994 Champ1 MGI:MGI:1196398|Ensembl:ENSMUSG00000047710|Vega:OTTMUSG00000022615 +101996 AI121036 MGI:MGI:2142465 +102009 AI195381 MGI:MGI:2142478 +102015 AI225912 MGI:MGI:2142484 +102022 Ces2a MGI:MGI:2142491|Ensembl:ENSMUSG00000055730|Vega:OTTMUSG00000027410 +102027 AI314604 MGI:MGI:2142496 +102029 AI315376 MGI:MGI:2142498 +102032 Smim19 MGI:MGI:2142501|Ensembl:ENSMUSG00000031534|Vega:OTTMUSG00000060888 +102058 Exoc8 MGI:MGI:2142527|Ensembl:ENSMUSG00000074030|Vega:OTTMUSG00000061569 +102060 Gadd45gip1 MGI:MGI:1914947|Ensembl:ENSMUSG00000033751|Vega:OTTMUSG00000029999 +102075 Plekhg4 MGI:MGI:2142544|Ensembl:ENSMUSG00000014782|Vega:OTTMUSG00000033516 +102093 Phkb MGI:MGI:97578|Ensembl:ENSMUSG00000036879|Vega:OTTMUSG00000031187 +102098 Arhgef18 MGI:MGI:2142567|Ensembl:ENSMUSG00000004568|Vega:OTTMUSG00000030752 +102099 AI480608 MGI:MGI:2142568 +102103 Mtus1 MGI:MGI:2142572|Ensembl:ENSMUSG00000045636|Vega:OTTMUSG00000031646 +102115 Dohh MGI:MGI:1915964|Ensembl:ENSMUSG00000078440|Vega:OTTMUSG00000030387 +102122 Fam192a MGI:MGI:1919637|Ensembl:ENSMUSG00000031774|Vega:OTTMUSG00000061667 +102124 Enkd1 MGI:MGI:2142593|Ensembl:ENSMUSG00000013155|Vega:OTTMUSG00000062055 +102132 E230013L22Rik MGI:MGI:2142601|Ensembl:ENSMUSG00000096957 +102141 Snx25 MGI:MGI:2142610|Ensembl:ENSMUSG00000038291|Vega:OTTMUSG00000024631 +102142 AI662245 MGI:MGI:2142611 +102144 AI746383 MGI:MGI:2142613 +102153 C230098O21Rik MGI:MGI:2142622 +102162 Taf5l MGI:MGI:1919039|Ensembl:ENSMUSG00000038697|Vega:OTTMUSG00000062008 +102182 Prmt9 MGI:MGI:2142651|Ensembl:ENSMUSG00000037134|Vega:OTTMUSG00000030761 +102186 A730070K21Rik MGI:MGI:2142655 +102193 Zdhhc7 MGI:MGI:2142662|Ensembl:ENSMUSG00000031823|Vega:OTTMUSG00000027531 +102197 AL024413 MGI:MGI:2142666 +102207 AU015590 MGI:MGI:2142676 +102209 Snapc2 MGI:MGI:1914861|Ensembl:ENSMUSG00000011837|Vega:OTTMUSG00000059345 +102210 AU015696 MGI:MGI:2142679 +102211 AU015777 MGI:MGI:2142680 +102219 AU018794 MGI:MGI:2142688 +102220 E330037G11Rik MGI:MGI:2142689 +102224 AU019542 MGI:MGI:2142693 +102225 AU019559 MGI:MGI:2142694 +102226 AU020147 MGI:MGI:2142695 +102229 AU021186 MGI:MGI:2142698 +102232 AU022186 MGI:MGI:2142701 +102233 AU022202 MGI:MGI:2142702 +102234 AU022229 MGI:MGI:2142703 +102240 AU022882 MGI:MGI:2142709 +102242 AU024180 MGI:MGI:2142711 +102243 AU024581 MGI:MGI:2142712 +102247 Gpat4 MGI:MGI:2142716|Ensembl:ENSMUSG00000031545|Vega:OTTMUSG00000060899 +102254 AU045717 MGI:MGI:2142723 +102265 AV026068 MGI:MGI:2142734 +102278 Cpne7 MGI:MGI:2142747|Ensembl:ENSMUSG00000034796|Vega:OTTMUSG00000027555 +102293 AW111846 MGI:MGI:2142762 +102294 Cyp4v3 MGI:MGI:2142763|Ensembl:ENSMUSG00000079057|Vega:OTTMUSG00000026456 +102323 Dcun1d2 MGI:MGI:2142792|Ensembl:ENSMUSG00000038506|Vega:OTTMUSG00000056854 +102334 Ankrd10 MGI:MGI:1921840|Ensembl:ENSMUSG00000031508|Vega:OTTMUSG00000060768 +102339 Cog4 MGI:MGI:2142808|Ensembl:ENSMUSG00000031753|Vega:OTTMUSG00000037836 +102344 9430047G12Rik MGI:MGI:2142813 +102348 AW743432 MGI:MGI:2142817 +102363 BB157005 MGI:MGI:2142832 +102366 BB211804 MGI:MGI:2142835 +102371 Myzap MGI:MGI:2142908|Ensembl:ENSMUSG00000041361|Ensembl:ENSMUSG00000092137|Vega:OTTMUSG00000036055|Vega:OTTMUSG00000036492 +102372 AA407434 MGI:MGI:2142909 +102380 D9Mgi32 MGI:MGI:2142917 +102383 AA408396 MGI:MGI:2142920 +102391 AA408954 MGI:MGI:2142928 +102401 AA414903 MGI:MGI:2142938 +102402 AA414992 MGI:MGI:2142939|Ensembl:ENSMUSG00000113342 +102405 AA511254 MGI:MGI:2142942 +102407 AA517031 MGI:MGI:2142944 +102408 AA517033 MGI:MGI:2142945 +102410 AA517548 MGI:MGI:2142947 +102411 AA517566 MGI:MGI:2142948 +102412 AA517656 MGI:MGI:2142949 +102413 AA517837 MGI:MGI:2142950 +102414 Clk3 MGI:MGI:1098670|Ensembl:ENSMUSG00000032316|Vega:OTTMUSG00000063206 +102421 AA589408 MGI:MGI:2142958 +102422 AA589418 MGI:MGI:2142959 +102423 Hinfp MGI:MGI:2429620|Ensembl:ENSMUSG00000032119|Vega:OTTMUSG00000063231 +102436 Lars2 MGI:MGI:2142973|Ensembl:ENSMUSG00000035202|Vega:OTTMUSG00000062845 +102437 AI036347 MGI:MGI:2142974 +102440 AI115463 MGI:MGI:2142977 +102442 Dennd4a MGI:MGI:2142979|Ensembl:ENSMUSG00000053641|Vega:OTTMUSG00000062613 +102447 AI120157 MGI:MGI:2142984 +102448 Xylb MGI:MGI:2142985|Ensembl:ENSMUSG00000035769|Vega:OTTMUSG00000062988 +102454 AI197427 MGI:MGI:2142991 +102459 AI255207 MGI:MGI:2142996 +102462 Imp3 MGI:MGI:1916119|Ensembl:ENSMUSG00000032288|Vega:OTTMUSG00000033769 +102502 Pls1 MGI:MGI:104809|Ensembl:ENSMUSG00000049493|Vega:OTTMUSG00000030784 +102524 AI451250 MGI:MGI:2143061 +102531 AI464180 MGI:MGI:2143068 +102533 AI465300 MGI:MGI:2143070 +102540 AI480624 MGI:MGI:2143077 +102542 AI480769 MGI:MGI:2143079 +102545 Cmtm7 MGI:MGI:2447166|Ensembl:ENSMUSG00000032436|Vega:OTTMUSG00000062859 +102566 Ano10 MGI:MGI:2143103|Ensembl:ENSMUSG00000037949|Vega:OTTMUSG00000062719 +102570 Slc22a13 MGI:MGI:2143107|Ensembl:ENSMUSG00000074028|Vega:OTTMUSG00000062976 +102573 AI662168 MGI:MGI:2143110 +102580 Alg9 MGI:MGI:1924753|Ensembl:ENSMUSG00000032059|Vega:OTTMUSG00000034198 +102589 AI835735 MGI:MGI:2143126 +102595 Plekho2 MGI:MGI:2143132|Ensembl:ENSMUSG00000050721|Vega:OTTMUSG00000062639 +102596 AI842136 MGI:MGI:2143133 +102607 Snx19 MGI:MGI:1921581|Ensembl:ENSMUSG00000031993|Vega:OTTMUSG00000062819 +102614 Rpp25 MGI:MGI:2143151|Ensembl:ENSMUSG00000062309|Vega:OTTMUSG00000063186 +102626 Mapkapk3 MGI:MGI:2143163|Ensembl:ENSMUSG00000032577|Vega:OTTMUSG00000030250 +102632 Acad11 MGI:MGI:2143169|Ensembl:ENSMUSG00000090150|Vega:OTTMUSG00000031729 +102634 AL022681 MGI:MGI:2143171 +102635 AL022780 MGI:MGI:2143172 +102638 AL022900 MGI:MGI:2143175 +102640 AL022988 MGI:MGI:2143177 +102642 AL024003 MGI:MGI:2143179 +102644 Oaf MGI:MGI:94852|Ensembl:ENSMUSG00000032014|Vega:OTTMUSG00000063150 +102645 B930001P03Rik MGI:MGI:2143182 +102650 AU014965 MGI:MGI:2143187 +102652 AU015086 MGI:MGI:2143189 +102657 Cd276 MGI:MGI:2183926|Ensembl:ENSMUSG00000035914|Vega:OTTMUSG00000063283 +102675 AU021933 MGI:MGI:2143212 +102676 AU022048 MGI:MGI:2143213 +102678 AU022331 MGI:MGI:2143215 +102680 Slc6a20a MGI:MGI:2143217|Ensembl:ENSMUSG00000036814|Vega:OTTMUSG00000036109 +102681 AU022707 MGI:MGI:2143218 +102685 AU023386 MGI:MGI:2143222 +102688 AU023762 MGI:MGI:2143225|Ensembl:ENSMUSG00000109890 +102690 AU024245 MGI:MGI:2143227 +102691 AU024783 MGI:MGI:2143228 +102693 Phldb1 MGI:MGI:2143230|Ensembl:ENSMUSG00000048537|Vega:OTTMUSG00000033492 +102722 AV064505 MGI:MGI:2143259|Ensembl:ENSMUSG00000086381 +102731 4833445I07Rik MGI:MGI:2143268 +102742 AW047749 MGI:MGI:2143279 +102747 Lrrc49 MGI:MGI:2442689|Ensembl:ENSMUSG00000047766|Vega:OTTMUSG00000023677 +102774 Bbs4 MGI:MGI:2143311|Ensembl:ENSMUSG00000025235|Vega:OTTMUSG00000063292 +102787 AW552889 MGI:MGI:2143324 +102791 Tcta MGI:MGI:1918829|Ensembl:ENSMUSG00000039461|Vega:OTTMUSG00000050751 +102808 AW742521 MGI:MGI:2143345 +102809 AW742630 MGI:MGI:2143346 +102810 AW742856 MGI:MGI:2143347 +102811 AW743293 MGI:MGI:2143348 +102814 AW821994 MGI:MGI:2143351 +102831 BB181994 MGI:MGI:2143368 +102836 BB236558 MGI:MGI:2143373 +102852 A130057A22Rik MGI:MGI:2147829 +102853 AA517446 MGI:MGI:2147830 +102854 AA517478 MGI:MGI:2147831 +102857 Slc6a8 MGI:MGI:2147834|Ensembl:ENSMUSG00000019558|Vega:OTTMUSG00000017696 +102864 DXMgi26 MGI:MGI:2147841 +102866 Pls3 MGI:MGI:104807|Ensembl:ENSMUSG00000016382|Vega:OTTMUSG00000017411 +102871 D330045A20Rik MGI:MGI:2147848|Ensembl:ENSMUSG00000042498|Vega:OTTMUSG00000018703 +102881 AI256676 MGI:MGI:2147858 +102913 6330509M05Rik MGI:MGI:2147890 +102916 AI451458 MGI:MGI:2147893 +102917 AI462521 MGI:MGI:2147894 +102920 Cenpi MGI:MGI:2147897|Ensembl:ENSMUSG00000031262|Vega:OTTMUSG00000019228 +102926 Atg4a-ps MGI:MGI:3615624 +102941 B630019K06Rik MGI:MGI:2147918|Ensembl:ENSMUSG00000052364|Vega:OTTMUSG00000016905 +102954 Nudt10 MGI:MGI:2147931|Ensembl:ENSMUSG00000073293|Vega:OTTMUSG00000016657 +102975 AU015621 MGI:MGI:2147952 +102985 AU020096 MGI:MGI:2147962 +102988 AU021864 MGI:MGI:2147965 +102989 AU022052 MGI:MGI:2147966 +102990 AU022409 MGI:MGI:2147967 +102991 AU022751 MGI:MGI:2147968|Ensembl:ENSMUSG00000073294|Vega:OTTMUSG00000016674 +102992 AU022788 MGI:MGI:2147969 +102993 AU022951 MGI:MGI:2147970 +103012 Firre MGI:MGI:2147989|Ensembl:ENSMUSG00000085396 +103014 AW060748 MGI:MGI:2147991 +103052 AW822039 MGI:MGI:2148029 +103067 AA522020 MGI:MGI:2148088 +103079 AA408251 MGI:MGI:2143465 +103080 Sept10 MGI:MGI:1918110|Ensembl:ENSMUSG00000019917 +103086 AA409749 MGI:MGI:2143472 +103093 AA516624 MGI:MGI:2143479 +103094 AA516847 MGI:MGI:2143480 +103096 AA522026 MGI:MGI:2143482 +103098 Slc6a15 MGI:MGI:2143484|Ensembl:ENSMUSG00000019894 +103104 AA545197 MGI:MGI:2143490 +103112 AA589531 MGI:MGI:2143498 +103113 AA589562 MGI:MGI:2143499 +103117 AA591064 MGI:MGI:2143503 +103135 Pan2 MGI:MGI:1918984|Ensembl:ENSMUSG00000005682 +103136 Pwp1 MGI:MGI:1914735|Ensembl:ENSMUSG00000001785 +103140 Gstt3 MGI:MGI:2143526|Ensembl:ENSMUSG00000001665|Vega:OTTMUSG00000031847 +103141 AI120166 MGI:MGI:2143527 +103142 Rdh9 MGI:MGI:2143528|Ensembl:ENSMUSG00000056148|Vega:OTTMUSG00000027659 +103149 Upb1 MGI:MGI:2143535|Ensembl:ENSMUSG00000033427|Vega:OTTMUSG00000031799 +103161 Apof MGI:MGI:104539|Ensembl:ENSMUSG00000047631 +103172 Chchd10 MGI:MGI:2143558|Ensembl:ENSMUSG00000049422 +103175 D630029K05Rik MGI:MGI:2143561|Ensembl:ENSMUSG00000031294 +103183 AI316838 MGI:MGI:2143569 +103199 Fig4 MGI:MGI:2143585|Ensembl:ENSMUSG00000038417|Vega:OTTMUSG00000063441 +103203 AI413759 MGI:MGI:2143589 +103210 D630004K10Rik MGI:MGI:2143596 +103213 Traf3ip2 MGI:MGI:2143599|Ensembl:ENSMUSG00000019842|Vega:OTTMUSG00000031773 +103214 Ifngas1 MGI:MGI:1934663|Ensembl:ENSMUSG00000112230 +103219 AI449547 MGI:MGI:2143605 +103220 Ttc41 MGI:MGI:2387653|Ensembl:ENSMUSG00000044937 +103232 Gm15122 MGI:MGI:3705268 +103236 Csnk1g2 MGI:MGI:1920014|Ensembl:ENSMUSG00000003345 +103266 Tmem263 MGI:MGI:2143652|Ensembl:ENSMUSG00000060935|Vega:OTTMUSG00000063530 +103268 Cep57l1 MGI:MGI:1915511|Ensembl:ENSMUSG00000019813|Vega:OTTMUSG00000045012 +103284 Zc3h10 MGI:MGI:2143670|Ensembl:ENSMUSG00000039810|Vega:OTTMUSG00000020848 +103288 AI836737 MGI:MGI:2143674 +103324 Gm4735 MGI:MGI:3645521 +103333 AU014973 MGI:MGI:2143719 +103334 AU015148 MGI:MGI:2143720 +103335 AU015253 MGI:MGI:2143721 +103336 AU015603 MGI:MGI:2143722 +103338 AU015740 MGI:MGI:2143724 +103339 AU016128 MGI:MGI:2143725 +103341 AU017962 MGI:MGI:2143727 +103343 AU018587 MGI:MGI:2143729 +103347 AU019202 MGI:MGI:2143733 +103354 AU021720 MGI:MGI:2143740 +103356 AU022054 MGI:MGI:2143742 +103358 AU022077 MGI:MGI:2143744 +103363 AU022778 MGI:MGI:2143749 +103364 AU022934 MGI:MGI:2143750 +103372 AU041419 MGI:MGI:2143758 +103405 4932439E07Rik MGI:MGI:2143791 +103406 Zfr2 MGI:MGI:2143792|Ensembl:ENSMUSG00000034949|Vega:OTTMUSG00000030338 +103409 AW046457 MGI:MGI:2143795 +103425 Ncln MGI:MGI:1926081|Ensembl:ENSMUSG00000020238|Vega:OTTMUSG00000030445 +103432 6430706H07Rik MGI:MGI:2143818 +103466 Nt5dc3 MGI:MGI:3513266|Ensembl:ENSMUSG00000054027 +103468 Nup107 MGI:MGI:2143854|Ensembl:ENSMUSG00000052798 +103480 AW552990 MGI:MGI:2143866 +103489 AW742317 MGI:MGI:2143875 +103491 AW742410 MGI:MGI:2143877 +103495 AW742733 MGI:MGI:2143881 +103497 AW743384 MGI:MGI:2143883 +103498 AW743424 MGI:MGI:2143884 +103499 AW821966 MGI:MGI:2143885 +103505 BB019430 MGI:MGI:2143891|Ensembl:ENSMUSG00000091526 +103510 D10Mgi24 MGI:MGI:2143896 +103511 Fam26e MGI:MGI:2143897|Ensembl:ENSMUSG00000049872 +103514 BB165335 MGI:MGI:2143900 +103517 BB187676 MGI:MGI:2143903 +103519 BB188282 MGI:MGI:2143905 +103534 Mgat4b MGI:MGI:2143974|Ensembl:ENSMUSG00000036620|Vega:OTTMUSG00000005573 +103537 Mbtd1 MGI:MGI:2143977|Ensembl:ENSMUSG00000059474|Vega:OTTMUSG00000001464 +103551 Epop MGI:MGI:2143991|Ensembl:ENSMUSG00000043439|Vega:OTTMUSG00000002746 +103554 Psme4 MGI:MGI:2143994|Ensembl:ENSMUSG00000040850|Vega:OTTMUSG00000005356 +103557 AA409525 MGI:MGI:2143997 +103569 AA414993 MGI:MGI:2144009 +103570 AA415038 MGI:MGI:2144010 +103573 Xpo1 MGI:MGI:2144013|Ensembl:ENSMUSG00000020290|Vega:OTTMUSG00000005274 +103574 AA511248 MGI:MGI:2144014 +103575 AA516831 MGI:MGI:2144015 +103578 AA517471 MGI:MGI:2144018 +103579 AA517833 MGI:MGI:2144019 +103580 AA522019 MGI:MGI:2144020 +103583 Fbxw11 MGI:MGI:2144023|Ensembl:ENSMUSG00000020271|Vega:OTTMUSG00000005386 +103590 AA589486 MGI:MGI:2144030 +103593 AA589579 MGI:MGI:2144033 +103597 AA591041 MGI:MGI:2144037 +103609 AA939960 MGI:MGI:2144049 +103629 AI117581 MGI:MGI:2144069 +103647 AI225885 MGI:MGI:2144087 +103653 AI256354 MGI:MGI:2144093 +103655 Sec14l4 MGI:MGI:2144095|Ensembl:ENSMUSG00000019368|Vega:OTTMUSG00000005051 +103659 AI256734 MGI:MGI:2144099 +103661 AI256777 MGI:MGI:2144101 +103672 AI316784 MGI:MGI:2144112 +103677 Smg6 MGI:MGI:2144117|Ensembl:ENSMUSG00000038290|Vega:OTTMUSG00000006198 +103694 Tmed4 MGI:MGI:1915070|Ensembl:ENSMUSG00000004394|Vega:OTTMUSG00000000780 +103710 Slc35e4 MGI:MGI:2144150|Ensembl:ENSMUSG00000048807|Vega:OTTMUSG00000005040 +103711 Pnpo MGI:MGI:2144151|Ensembl:ENSMUSG00000018659|Vega:OTTMUSG00000001731 +103712 6330403K07Rik MGI:MGI:1918001 +103724 Tbc1d10a MGI:MGI:2144164|Ensembl:ENSMUSG00000034412|Vega:OTTMUSG00000005055 +103727 Gm11520 MGI:MGI:3650534 +103729 AI450353 MGI:MGI:2144169 +103733 Tubg1 MGI:MGI:101834|Ensembl:ENSMUSG00000035198|Vega:OTTMUSG00000002704 +103737 Pex12 MGI:MGI:2144177|Ensembl:ENSMUSG00000018733|Vega:OTTMUSG00000000912 +103742 Mien1 MGI:MGI:1913678|Ensembl:ENSMUSG00000002580|Vega:OTTMUSG00000006365 +103743 Tmem98 MGI:MGI:1923457|Ensembl:ENSMUSG00000035413|Vega:OTTMUSG00000000222 +103745 AI464234 MGI:MGI:2144185 +103762 AI503301 MGI:MGI:2144202 +103765 Tmem17 MGI:MGI:2144205|Ensembl:ENSMUSG00000049904|Vega:OTTMUSG00000005259 +103767 A530047J11Rik MGI:MGI:2144207 +103768 Tubg2 MGI:MGI:2144208|Ensembl:ENSMUSG00000045007|Vega:OTTMUSG00000002705 +103775 Slc25a41 MGI:MGI:2144215|Ensembl:ENSMUSG00000011486|Vega:OTTMUSG00000035804 +103784 Wdr92 MGI:MGI:2144224|Ensembl:ENSMUSG00000078970|Vega:OTTMUSG00000005194 +103793 9430098F02Rik MGI:MGI:2144233 +103795 AI594671 MGI:MGI:2144235 +103797 AI596487 MGI:MGI:2144237 +103800 AI606797 MGI:MGI:2144240 +103806 Maml1 MGI:MGI:1890504|Ensembl:ENSMUSG00000050567|Vega:OTTMUSG00000005580 +103816 AI662461 MGI:MGI:2144256 +103817 AI662501 MGI:MGI:2144257 +103819 AI663975 MGI:MGI:2144259 +103836 Zfp692 MGI:MGI:2144276|Ensembl:ENSMUSG00000037243|Vega:OTTMUSG00000005728 +103841 Cuedc1 MGI:MGI:2144281|Ensembl:ENSMUSG00000018378|Vega:OTTMUSG00000001478 +103844 Inca1 MGI:MGI:2144284|Ensembl:ENSMUSG00000057054|Vega:OTTMUSG00000006067 +103846 AI845619 MGI:MGI:2144286 +103850 Nt5m MGI:MGI:1917127|Ensembl:ENSMUSG00000032615|Vega:OTTMUSG00000008096 +103875 AI853502 MGI:MGI:2144315 +103889 Hoxb2 MGI:MGI:96183|Ensembl:ENSMUSG00000075588|Vega:OTTMUSG00000001779 +103900 AL022704 MGI:MGI:2144340 +103912 Wo MGI:MGI:98963 +103917 Sagg MGI:MGI:1861992 +103919 Ty MGI:MGI:98876 +103920 Sic MGI:MGI:1861984 +103921 Fers MGI:MGI:1861994 +103922 Fk MGI:MGI:95539 +103927 Ht MGI:MGI:96264 +103929 Ng MGI:MGI:97318 +103930 Vng MGI:MGI:1861989 +103931 U MGI:MGI:98883 +103932 Pv MGI:MGI:97820 +103935 Eh MGI:MGI:95297 +103936 Frl MGI:MGI:95579 +103937 Nano MGI:MGI:1861998 +103942 Whto MGI:MGI:1861986 +103943 Es24 MGI:MGI:95436 +103946 Br MGI:MGI:88189 +103948 Rn7s1 MGI:MGI:97950|Ensembl:ENSMUSG00000099021 +103949 Rn7s2 MGI:MGI:97953|Ensembl:ENSMUSG00000099250 +103950 Rn7s3 MGI:MGI:97954 +103951 Rn7s5 MGI:MGI:97955 +103952 Rn7s9 MGI:MGI:97958 +103953 Rn7sX MGI:MGI:97959 +103957 Tyl MGI:MGI:98877 +103958 Rn7s4 MGI:MGI:103066 +103959 Ubb3 MGI:MGI:106680 +103962 Rf MGI:MGI:97903 +103963 Rpn1 MGI:MGI:98084|Ensembl:ENSMUSG00000030062|Vega:OTTMUSG00000057340 +103964 Try5 MGI:MGI:102756|Ensembl:ENSMUSG00000036938|Vega:OTTMUSG00000026909 +103967 Dnm3 MGI:MGI:1341299|Ensembl:ENSMUSG00000040265|Vega:OTTMUSG00000029472 +103968 Plin1 MGI:MGI:1890505|Ensembl:ENSMUSG00000030546|Vega:OTTMUSG00000058580 +103971 Eo MGI:MGI:95396 +103973 Rn7s12 MGI:MGI:97951 +103974 Rn7s13 MGI:MGI:97952 +103975 Rn7s10 MGI:MGI:103065 +103978 Gpc5 MGI:MGI:1194894|Ensembl:ENSMUSG00000022112|Vega:OTTMUSG00000042137 +103979 Alph1 MGI:MGI:88043 +103980 Alph2 MGI:MGI:88044 +103981 Es15 MGI:MGI:95426 +103983 Imp1 MGI:MGI:96566 +103984 It MGI:MGI:96598 +103985 Skn1 MGI:MGI:98311 +103986 Wt MGI:MGI:98967 +103988 Gck MGI:MGI:1270854|Ensembl:ENSMUSG00000041798|Vega:OTTMUSG00000006327 +103993 Bsp MGI:MGI:88210 +103995 Hist1-1s MGI:MGI:96094 +103996 Lse MGI:MGI:96831 +103997 Dpa MGI:MGI:108553 +103999 Strg MGI:MGI:1861997 +104000 Priap1 MGI:MGI:1890565 +104001 Rtn1 MGI:MGI:1933947|Ensembl:ENSMUSG00000021087|Vega:OTTMUSG00000016329 +104002 Ctsq MGI:MGI:2137385|Ensembl:ENSMUSG00000021439|Vega:OTTMUSG00000027750 +104009 Qsox1 MGI:MGI:1330818|Ensembl:ENSMUSG00000033684|Vega:OTTMUSG00000025411 +104010 Cdh22 MGI:MGI:1341843|Ensembl:ENSMUSG00000053166|Vega:OTTMUSG00000001155 +104012 Axd MGI:MGI:88125 +104015 Synj1 MGI:MGI:1354961|Ensembl:ENSMUSG00000022973|Vega:OTTMUSG00000027935 +104017 Em MGI:MGI:95319 +104021 Hist1-2bs MGI:MGI:96095 +104022 Ie MGI:MGI:96419 +104023 Qd MGI:MGI:97834 +104027 Synpo MGI:MGI:1099446|Ensembl:ENSMUSG00000043079|Vega:OTTMUSG00000033190 +104029 Cp2 MGI:MGI:88477 +104030 Cyl MGI:MGI:88580 +104033 Dfp2 MGI:MGI:1861991 +104036 Lop3 MGI:MGI:96809 +104037 Lop5 MGI:MGI:96811 +104038 Lop6 MGI:MGI:96812 +104039 Lop7 MGI:MGI:96813 +104040 Lop8 MGI:MGI:96814 +104041 Lop9 MGI:MGI:96815 +104042 Trp2 MGI:MGI:98833 +104044 Sta MGI:MGI:98428 +104045 Gtl8 MGI:MGI:1309471 +104046 Mom6 MGI:MGI:1913164 +104054 Ga MGI:MGI:95608 +104055 Hst3 MGI:MGI:96260 +104057 Mal1 MGI:MGI:96914 +104058 Panc2 MGI:MGI:97477 +104063 Gtl9 MGI:MGI:1309470 +104065 Mgpt1 MGI:MGI:96978 +104066 Panc1 MGI:MGI:97476 +104067 Pol1 MGI:MGI:97726 +104069 Sncb MGI:MGI:1889011|Ensembl:ENSMUSG00000034891|Vega:OTTMUSG00000032668 +104070 Gdr1 MGI:MGI:95694 +104072 Tol1 MGI:MGI:98787 +104073 Up MGI:MGI:98908 +104079 Nxph3 MGI:MGI:1336188|Ensembl:ENSMUSG00000046719|Vega:OTTMUSG00000001660 +104080 Nxph4 MGI:MGI:1336197|Ensembl:ENSMUSG00000040258|Vega:OTTMUSG00000035297 +104082 Wdr7 MGI:MGI:1860197|Ensembl:ENSMUSG00000040560 +104083 Bfo MGI:MGI:88149 +104086 Cyp27a1 MGI:MGI:88594|Ensembl:ENSMUSG00000026170|Vega:OTTMUSG00000048252 +104087 Dre MGI:MGI:94928 +104088 Exa MGI:MGI:95464 +104089 Hct MGI:MGI:96059 +104090 Hxa MGI:MGI:96291 +104091 Ir1 MGI:MGI:96583 +104092 Ir3 MGI:MGI:96585 +104093 Ir4 MGI:MGI:96586 +104095 Ir8 MGI:MGI:96589 +104096 Pol16 MGI:MGI:97729 +104097 Pol27 MGI:MGI:97735 +104098 Xpl MGI:MGI:99136 +104099 Itga9 MGI:MGI:104756|Ensembl:ENSMUSG00000039115|Vega:OTTMUSG00000033312 +104101 Gtayu3 MGI:MGI:1100491 +104103 Airn MGI:MGI:1353471|Ensembl:ENSMUSG00000078247 +104104 Ath2 MGI:MGI:88099 +104105 Ath7 MGI:MGI:88102 +104106 Ath8 MGI:MGI:88103 +104107 Pol17 MGI:MGI:97730 +104108 Segr MGI:MGI:98276 +104110 Adcy4 MGI:MGI:99674|Ensembl:ENSMUSG00000022220 +104111 Adcy3 MGI:MGI:99675|Ensembl:ENSMUSG00000020654|Vega:OTTMUSG00000033731 +104112 Acly MGI:MGI:103251|Ensembl:ENSMUSG00000020917|Vega:OTTMUSG00000006279 +104113 Act3 MGI:MGI:108060 +104116 H29 MGI:MGI:95976 +104117 H35 MGI:MGI:95983 +104118 H37 MGI:MGI:95985 +104119 H48 MGI:MGI:95995 +104120 H52 MGI:MGI:95999 +104121 Lar MGI:MGI:96751 +104122 Lpn1 MGI:MGI:96821 +104123 Lpn2 MGI:MGI:96822 +104124 Meta MGI:MGI:96971 +104126 Lith3 MGI:MGI:102582 +104127 Lith2 MGI:MGI:102583 +104128 Egm2 MGI:MGI:1261420 +104130 Ndufb11 MGI:MGI:1349919|Ensembl:ENSMUSG00000031059|Vega:OTTMUSG00000017084 +104132 Ads4 MGI:MGI:87946 +104133 H17 MGI:MGI:95889 +104134 H19h MGI:MGI:95892 +104135 H34 MGI:MGI:95982 +104136 H38 MGI:MGI:95986 +104137 H40 MGI:MGI:95987 +104138 H50 MGI:MGI:95997 +104139 H53 MGI:MGI:96000 +104140 H55 MGI:MGI:96002 +104141 H57 MGI:MGI:96003 +104142 Len2 MGI:MGI:96772 +104143 Ly36 MGI:MGI:96872 +104144 Mv MGI:MGI:97242 +104145 Pp MGI:MGI:97745 +104146 Cgct MGI:MGI:88242 +104147 Dmc MGI:MGI:94908 +104148 Lvs MGI:MGI:96855 +104149 Ly16 MGI:MGI:96860 +104151 Phmr MGI:MGI:97580 +104153 Spl MGI:MGI:98381 +104154 Tsv MGI:MGI:98860 +104155 Lamr2 MGI:MGI:105309 +104156 Etv5 MGI:MGI:1096867|Ensembl:ENSMUSG00000013089|Vega:OTTMUSG00000036714 +104158 Ces1d MGI:MGI:2148202|Ensembl:ENSMUSG00000056973|Vega:OTTMUSG00000024539 +104159 Epa1 MGI:MGI:95400 +104160 H9 MGI:MGI:96008 +104161 Lyb6 MGI:MGI:96889 +104162 Lyx1 MGI:MGI:96894 +104163 Lyx2 MGI:MGI:96895 +104164 Lyx3 MGI:MGI:96896 +104165 Met2 MGI:MGI:96970 +104167 Pd MGI:MGI:97522 +104168 Rmp1 MGI:MGI:97934 +104169 Gtl11 MGI:MGI:1309475 +104170 Gtl10 MGI:MGI:1309476 +104171 Gtl12 MGI:MGI:1309477 +104173 Cypr3 MGI:MGI:1333845 +104174 Gldc MGI:MGI:1341155|Ensembl:ENSMUSG00000024827 +104175 Sbk1 MGI:MGI:2135937|Ensembl:ENSMUSG00000042978|Vega:OTTMUSG00000058209 +104176 Ly8 MGI:MGI:96884 +104177 Lyb7 MGI:MGI:96890 +104179 Srv MGI:MGI:98422 +104180 Zfp56 MGI:MGI:99203 +104183 Chil4 MGI:MGI:1341098|Ensembl:ENSMUSG00000063779|Vega:OTTMUSG00000016670 +104184 Blmh MGI:MGI:1345186|Ensembl:ENSMUSG00000020840|Vega:OTTMUSG00000006244 +104187 Lm1 MGI:MGI:96793 +104188 Lna1 MGI:MGI:96802 +104189 Lpn3 MGI:MGI:96823 +104190 Po MGI:MGI:97725 +104191 Sgp2 MGI:MGI:98291 +104192 Meng MGI:MGI:107463 +104193 Ce1 MGI:MGI:88363 +104194 Ea2 MGI:MGI:95265 +104196 Ea5 MGI:MGI:95268 +104197 Ea7 MGI:MGI:95270 +104199 H10 MGI:MGI:95883 +104200 H11 MGI:MGI:95884 +104201 H12 MGI:MGI:95885 +104203 H27 MGI:MGI:95974 +104204 H36 MGI:MGI:95984 +104205 H41 MGI:MGI:95988 +104206 Lzp-r MGI:MGI:96901 +104207 Mcpt3 MGI:MGI:96939 +104209 Ink76 MGI:MGI:99693 +104210 Aldr4 MGI:MGI:105040 +104211 Aldr2 MGI:MGI:105042 +104212 Tex5 MGI:MGI:105928 +104214 Clcnk2 MGI:MGI:1329028 +104215 Rhoq MGI:MGI:1931553|Ensembl:ENSMUSG00000024143|Vega:OTTMUSG00000024349 +104216 Ads2 MGI:MGI:87944 +104218 Dtc1 MGI:MGI:94934 +104219 Ly13 MGI:MGI:96858 +104220 Ly26 MGI:MGI:96865 +104221 Ly30 MGI:MGI:96868 +104225 Rmp2 MGI:MGI:97935 +104231 Ly76 MGI:MGI:106910 +104232 Ly79 MGI:MGI:107176 +104236 Aal MGI:MGI:87855 +104237 Apo MGI:MGI:88048 +104239 Eam MGI:MGI:95273 +104240 Jt1 MGI:MGI:96645 +104242 Mch MGI:MGI:96933 +104244 Sr1 MGI:MGI:98396 +104245 Slc6a5 MGI:MGI:105090|Ensembl:ENSMUSG00000039728|Vega:OTTMUSG00000059001 +104246 Msg MGI:MGI:107462 +104248 Cabin1 MGI:MGI:1298375|Ensembl:ENSMUSG00000020196 +104250 Ly99 MGI:MGI:1344423 +104252 Cdc42ep2 MGI:MGI:1929744|Ensembl:ENSMUSG00000045664 +104253 Ad MGI:MGI:87915 +104258 Lyb3 MGI:MGI:96886 +104259 Lyb5 MGI:MGI:96888 +104261 Rig2 MGI:MGI:97921 +104263 Kdm3a MGI:MGI:98847|Ensembl:ENSMUSG00000053470|Vega:OTTMUSG00000057914 +104264 Olfr14 MGI:MGI:104714 +104265 Trg1 MGI:MGI:104894 +104266 Tsp2 MGI:MGI:106194 +104267 Tsp5 MGI:MGI:107626 +104271 Tex15 MGI:MGI:1934816|Ensembl:ENSMUSG00000009628|Vega:OTTMUSG00000022964 +104272 Caf MGI:MGI:88243 +104277 Glud-ps MGI:MGI:95754 +104290 Pctr2 MGI:MGI:103068 +104293 Tsp7 MGI:MGI:107594 +104294 Tsp6 MGI:MGI:107597 +104297 Igis1 MGI:MGI:1890486 +104298 Exnm MGI:MGI:95467 +104299 Prt1 MGI:MGI:97777 +104300 Prt3 MGI:MGI:97778 +104301 Prt6 MGI:MGI:97781 +104303 Arl1 MGI:MGI:99436|Ensembl:ENSMUSG00000060904|Vega:OTTMUSG00000035178 +104307 Rnu12 MGI:MGI:1336893|Ensembl:ENSMUSG00000065176 +104310 Poo MGI:MGI:97743 +104318 Csnk1d MGI:MGI:1355272|Ensembl:ENSMUSG00000025162|Vega:OTTMUSG00000004159 +104320 Cfp1 MGI:MGI:88387 +104323 Emi1 MGI:MGI:95324 +104324 Hrs2 MGI:MGI:96228 +104325 Lzm-s2 MGI:MGI:96900 +104326 Mdmg1 MGI:MGI:96954 +104327 Mp MGI:MGI:97070 +104328 Hfh7 MGI:MGI:99898 +104329 Blai2 MGI:MGI:99947 +104333 Pira9 MGI:MGI:1195967 +104334 Pira8 MGI:MGI:1195968 +104337 Gct1 MGI:MGI:95677 +104339 O MGI:MGI:97393 +104342 Blai1 MGI:MGI:107409 +104346 Gas8 MGI:MGI:1202386|Ensembl:ENSMUSG00000040220|Vega:OTTMUSG00000061978 +104347 Cpza MGI:MGI:1298396 +104348 Zfp120 MGI:MGI:1345179|Ensembl:ENSMUSG00000068134|Vega:OTTMUSG00000015770 +104349 Zfp119a MGI:MGI:1345189|Ensembl:ENSMUSG00000057835|Vega:OTTMUSG00000045092 +104352 Nuca MGI:MGI:97387 +104353 Rec2 MGI:MGI:97889 +104354 Rep1 MGI:MGI:97900 +104355 Rnrc MGI:MGI:99688 +104356 Rnrb MGI:MGI:99689 +104358 n-THgtg8 MGI:MGI:4413898 +104360 Isl2 MGI:MGI:109156|Ensembl:ENSMUSG00000032318|Vega:OTTMUSG00000036076 +104362 Meig1 MGI:MGI:1202878|Ensembl:ENSMUSG00000026650|Vega:OTTMUSG00000010782 +104366 Snora64 MGI:MGI:2148175|Ensembl:ENSMUSG00000077709 +104367 Snora65 MGI:MGI:2148176|Ensembl:ENSMUSG00000065124 +104368 Snora70 MGI:MGI:2148178|Ensembl:ENSMUSG00000064981 +104369 Snora69 MGI:MGI:2148180|Ensembl:ENSMUSG00000065642 +104370 Snora68 MGI:MGI:2148181 +104371 Acc MGI:MGI:87872 +104374 Enc MGI:MGI:95391 +104375 Ezg MGI:MGI:95472 +104377 Iac MGI:MGI:96305 +104378 Srlv1 MGI:MGI:98420 +104382 Barhl2 MGI:MGI:1859314|Ensembl:ENSMUSG00000034384|Vega:OTTMUSG00000026737 +104383 Rcor2 MGI:MGI:1859854|Ensembl:ENSMUSG00000024968|Vega:OTTMUSG00000017295 +104384 Rhox9 MGI:MGI:1890128|Ensembl:ENSMUSG00000068048|Vega:OTTMUSG00000017132 +104385 Asc1 MGI:MGI:88079 +104386 Asc2 MGI:MGI:88080 +104387 Exi MGI:MGI:891993 +104389 Ifi12 MGI:MGI:96425 +104390 Melc MGI:MGI:96962 +104391 Rasl2-1 MGI:MGI:97862 +104394 E2f4 MGI:MGI:103012|Ensembl:ENSMUSG00000014859|Vega:OTTMUSG00000062044 +104397 Gtig1 MGI:MGI:1274792 +104401 Pcnx3 MGI:MGI:1861733|Ensembl:ENSMUSG00000054874|Vega:OTTMUSG00000033232 +104406 Exz1 MGI:MGI:95468 +104408 Hsp84-2 MGI:MGI:96248 +104416 Bap1 MGI:MGI:1206586|Ensembl:ENSMUSG00000021901|Vega:OTTMUSG00000048112 +104418 Dgkz MGI:MGI:1278339|Ensembl:ENSMUSG00000040479|Vega:OTTMUSG00000014363 +104422 Eem1 MGI:MGI:1913079 +104433 Snora62 MGI:MGI:2148179|Ensembl:ENSMUSG00000064925 +104434 Hsp84-3 MGI:MGI:96249 +104435 Rgv2 MGI:MGI:97910 +104436 Tpe2 MGI:MGI:103145 +104438 Cfp3 MGI:MGI:104980 +104439 Cfp2 MGI:MGI:104981 +104441 Tel-rs6 MGI:MGI:1101776 +104443 Npffr2 MGI:MGI:1860130|Ensembl:ENSMUSG00000035528|Vega:OTTMUSG00000026708 +104444 Rexo2 MGI:MGI:1888981|Ensembl:ENSMUSG00000032026|Vega:OTTMUSG00000063007 +104445 Cdc42ep1 MGI:MGI:1929763|Ensembl:ENSMUSG00000049521 +104447 AL024152 MGI:MGI:2144351 +104457 0610010K14Rik MGI:MGI:1915609|Ensembl:ENSMUSG00000020831|Vega:OTTMUSG00000006039 +104458 Rars MGI:MGI:1914297|Ensembl:ENSMUSG00000018848|Vega:OTTMUSG00000005415 +104462 AU014795 MGI:MGI:2144366 +104470 AU015555 MGI:MGI:2144374 +104479 Ccdc117 MGI:MGI:2144383|Ensembl:ENSMUSG00000020482|Vega:OTTMUSG00000005086 +104486 AU019300 MGI:MGI:2144390 +104506 AU022194 MGI:MGI:2144410 +104507 AU022238 MGI:MGI:2144411 +104509 AU022554 MGI:MGI:2144413 +104510 AU022579 MGI:MGI:2144414 +104522 AU040972 MGI:MGI:2144426|Ensembl:ENSMUSG00000091523 +104570 Ppp4r3b MGI:MGI:2144474|Ensembl:ENSMUSG00000020463|Vega:OTTMUSG00000005320 +104582 Rprml MGI:MGI:2144486|Ensembl:ENSMUSG00000046215|Vega:OTTMUSG00000003013 +104600 AW125324 MGI:MGI:2144504 +104601 Mycbpap MGI:MGI:2388726|Ensembl:ENSMUSG00000039110|Vega:OTTMUSG00000001997 +104625 Cnot6 MGI:MGI:2144529|Ensembl:ENSMUSG00000020362|Vega:OTTMUSG00000005565 +104662 Tsr1 MGI:MGI:2144566|Ensembl:ENSMUSG00000038335|Vega:OTTMUSG00000006188 +104677 AW610836 MGI:MGI:2144581 +104678 AW742696 MGI:MGI:2144582 +104679 9530018D06Rik MGI:MGI:2144583 +104681 Slc16a6 MGI:MGI:2144585|Ensembl:ENSMUSG00000041920|Vega:OTTMUSG00000003343 +104685 AW743339 MGI:MGI:2144589 +104692 Gm12108 MGI:MGI:3651176|Ensembl:ENSMUSG00000086386 +104697 BB122250 MGI:MGI:2144601 +104701 BB143651 MGI:MGI:2144605 +104705 BB162755 MGI:MGI:2144609 +104708 BB217526 MGI:MGI:2144612 +104709 Pik3r6 MGI:MGI:2144613|Ensembl:ENSMUSG00000046207|Vega:OTTMUSG00000005945 +104718 Ttc7b MGI:MGI:2144724|Ensembl:ENSMUSG00000033530 +104721 Ddx1 MGI:MGI:2144727|Ensembl:ENSMUSG00000037149 +104725 Sptssa MGI:MGI:1913399|Ensembl:ENSMUSG00000044408 +104728 AA415338 MGI:MGI:2144734 +104729 AA511268 MGI:MGI:2144735 +104730 AA516601 MGI:MGI:2144736 +104731 AA517849 MGI:MGI:2144737 +104732 4930427A07Rik MGI:MGI:2144738|Ensembl:ENSMUSG00000037466|Vega:OTTMUSG00000052483 +104733 AA536658 MGI:MGI:2144739 +104735 AA575097 MGI:MGI:2144741 +104738 AA589515 MGI:MGI:2144744 +104748 AF070003 MGI:MGI:2144754 +104750 AI035719 MGI:MGI:2144756 +104754 AI115515 MGI:MGI:2144760 +104759 Pld4 MGI:MGI:2144765|Ensembl:ENSMUSG00000052160 +104771 Jkamp MGI:MGI:1915057|Ensembl:ENSMUSG00000005078|Vega:OTTMUSG00000027642 +104776 Aldh6a1 MGI:MGI:1915077|Ensembl:ENSMUSG00000021238 +104783 AI316808 MGI:MGI:2144789 +104798 Sfta3-ps MGI:MGI:2144804|Ensembl:ENSMUSG00000112343 +104799 Vipas39 MGI:MGI:2144805|Ensembl:ENSMUSG00000021038 +104800 AI414330 MGI:MGI:2144806 +104806 Fancm MGI:MGI:2442306|Ensembl:ENSMUSG00000055884 +104812 AI428406 MGI:MGI:2144818 +104816 Aspg MGI:MGI:2144822|Ensembl:ENSMUSG00000037686 +104831 Ptpn23 MGI:MGI:2144837|Ensembl:ENSMUSG00000036057|Vega:OTTMUSG00000051578 +104836 Cbll1 MGI:MGI:2144842|Ensembl:ENSMUSG00000020659|Vega:OTTMUSG00000046950 +104859 Tecpr2 MGI:MGI:2144865|Ensembl:ENSMUSG00000021275 +104871 Spata7 MGI:MGI:2144877|Ensembl:ENSMUSG00000021007|Vega:OTTMUSG00000023264 +104884 Tdp1 MGI:MGI:1920036|Ensembl:ENSMUSG00000021177|Vega:OTTMUSG00000033586 +104885 Tmem179 MGI:MGI:2144891|Ensembl:ENSMUSG00000054013 +104886 Rab15 MGI:MGI:1916865|Ensembl:ENSMUSG00000021062|Vega:OTTMUSG00000027558 +104896 AI852580 MGI:MGI:2144902 +104910 Slc25a47 MGI:MGI:2144766|Ensembl:ENSMUSG00000048856 +104923 Adi1 MGI:MGI:2144929|Ensembl:ENSMUSG00000020629|Vega:OTTMUSG00000022994 +104930 AU015738 MGI:MGI:2144936 +104932 AU015791 MGI:MGI:2144938 +104936 AU017263 MGI:MGI:2144942 +104943 Fam110c MGI:MGI:1918813|Ensembl:ENSMUSG00000036136 +104945 AU019868 MGI:MGI:2144951 +104946 D12Mgi38 MGI:MGI:2144952 +104950 AU021977 MGI:MGI:2144956 +104952 AU022348 MGI:MGI:2144958 +104981 AV259865 MGI:MGI:2144987 +104993 AW060763 MGI:MGI:2144999 +105000 Dnal1 MGI:MGI:1921462|Ensembl:ENSMUSG00000042523|Vega:OTTMUSG00000033876 +105005 Fam84a MGI:MGI:2145011|Ensembl:ENSMUSG00000020607 +105014 Rdh14 MGI:MGI:1920402|Ensembl:ENSMUSG00000020621 +105050 AW742725 MGI:MGI:2145056 +105052 D12Mgi44 MGI:MGI:2145058 +105053 AW743365 MGI:MGI:2145059 +105054 AW743876 MGI:MGI:2145060 +105055 AW822243 MGI:MGI:2145061 +105057 BB042571 MGI:MGI:2145063 +105058 BB044704 MGI:MGI:2145064 +105063 BB125219 MGI:MGI:2145069 +105070 AA407175 MGI:MGI:2145141 +105083 Pelo MGI:MGI:2145154|Ensembl:ENSMUSG00000042275 +105093 AA511260 MGI:MGI:2145164 +105094 AA516957 MGI:MGI:2145165 +105095 AA517650 MGI:MGI:2145166 +105096 AA517651 MGI:MGI:2145167 +105097 AA571384 MGI:MGI:2145168 +105108 AA986891 MGI:MGI:2145179 +105111 AI043046 MGI:MGI:2145182 +105120 AI197445 MGI:MGI:2145191 +105122 AI225925 MGI:MGI:2145193 +105123 AI256346 MGI:MGI:2145194 +105148 Iars MGI:MGI:2145219|Ensembl:ENSMUSG00000037851|Vega:OTTMUSG00000035300 +105163 AI429388 MGI:MGI:2145234 +105171 Arrdc3 MGI:MGI:2145242|Ensembl:ENSMUSG00000074794|Vega:OTTMUSG00000034707 +105183 AI462951 MGI:MGI:2145254 +105185 D130076G13Rik MGI:MGI:2145256 +105188 AI481207 MGI:MGI:2145259 +105193 Nhlrc1 MGI:MGI:2145264|Ensembl:ENSMUSG00000044231 +105203 Fam208b MGI:MGI:2145274|Ensembl:ENSMUSG00000033799 +105211 AI663969 MGI:MGI:2145282 +105239 Rnf44 MGI:MGI:2145310|Ensembl:ENSMUSG00000034928|Vega:OTTMUSG00000032674 +105243 Slc9a3 MGI:MGI:105064|Ensembl:ENSMUSG00000036123 +105245 Txndc5 MGI:MGI:2145316|Ensembl:ENSMUSG00000038991|Vega:OTTMUSG00000035033 +105246 Brd9 MGI:MGI:2145317|Ensembl:ENSMUSG00000057649 +105253 AL024213 MGI:MGI:2145324 +105259 AU015559 MGI:MGI:2145330 +105260 D930043N17Rik MGI:MGI:2145331 +105262 AU015723 MGI:MGI:2145333 +105264 AU016102 MGI:MGI:2145335 +105268 AU016916 MGI:MGI:2145339 +105271 AU017674 MGI:MGI:2145342 +105272 AU017834 MGI:MGI:2145343 +105273 AU018574 MGI:MGI:2145344 +105276 AU018877 MGI:MGI:2145347 +105278 Cdk20 MGI:MGI:2145349|Ensembl:ENSMUSG00000021483 +105281 AU019796 MGI:MGI:2145352 +105283 E030046B03Rik MGI:MGI:2145354 +105285 AU021025 MGI:MGI:2145356 +105289 AU021877 MGI:MGI:2145360 +105290 AU021895 MGI:MGI:2145361 +105291 AU022445 MGI:MGI:2145362 +105292 AU022746 MGI:MGI:2145363 +105298 Epdr1 MGI:MGI:2145369|Ensembl:ENSMUSG00000002808 +105301 AU042410 MGI:MGI:2145372 +105332 AW011956 MGI:MGI:2145403 +105348 Golm1 MGI:MGI:1917329|Ensembl:ENSMUSG00000021556 +105349 Akr1c18 MGI:MGI:2145420|Ensembl:ENSMUSG00000021214|Vega:OTTMUSG00000027950 +105351 AW209491 MGI:MGI:2145422|Ensembl:ENSMUSG00000039182 +105352 Dusp22 MGI:MGI:1915926|Ensembl:ENSMUSG00000069255|Vega:OTTMUSG00000000672 +105355 Slc17a3 MGI:MGI:2389216|Ensembl:ENSMUSG00000036083|Vega:OTTMUSG00000000574 +105364 AW495222 MGI:MGI:2145435|Ensembl:ENSMUSG00000087334 +105372 Utp15 MGI:MGI:2145443|Ensembl:ENSMUSG00000041747 +105377 Slf1 MGI:MGI:2145448|Ensembl:ENSMUSG00000021597|Vega:OTTMUSG00000033900 +105387 Akr1c14 MGI:MGI:2145458|Ensembl:ENSMUSG00000033715|Vega:OTTMUSG00000027938 +105391 AW742221 MGI:MGI:2145462 +105392 AW742350 MGI:MGI:2145463 +105393 AW742391 MGI:MGI:2145464 +105395 AW742635 MGI:MGI:2145466 +105396 AW742864 MGI:MGI:2145467 +105398 9330199F22Rik MGI:MGI:2145469 +105402 BB120430 MGI:MGI:2145473 +105404 BB123696 MGI:MGI:2145475 +105405 BB124184 MGI:MGI:2145476 +105407 BB189686 MGI:MGI:2145478 +105416 D14Mgi10 MGI:MGI:2145555 +105418 E330034G19Rik MGI:MGI:2145557|Ensembl:ENSMUSG00000038925|Vega:OTTMUSG00000034630 +105420 AA511280 MGI:MGI:2145559 +105421 AA516634 MGI:MGI:2145560 +105423 AA517116 MGI:MGI:2145562 +105425 B930053N05Rik MGI:MGI:2145564 +105426 AA517841 MGI:MGI:2145565 +105427 AA517858 MGI:MGI:2145566 +105428 Fam149b MGI:MGI:2145567|Ensembl:ENSMUSG00000039599 +105431 AA536951 MGI:MGI:2145570 +105438 AA673491 MGI:MGI:2145577 +105439 Slain1 MGI:MGI:2145578|Ensembl:ENSMUSG00000055717|Vega:OTTMUSG00000034692 +105440 Kctd9 MGI:MGI:2145579|Ensembl:ENSMUSG00000034327|Vega:OTTMUSG00000033570 +105442 B130052P14Rik MGI:MGI:2145581 +105445 Dock9 MGI:MGI:106321|Ensembl:ENSMUSG00000025558|Vega:OTTMUSG00000061831 +105446 Gmpr2 MGI:MGI:1917903|Ensembl:ENSMUSG00000002326 +105449 AA986715 MGI:MGI:2145588 +105450 Mmrn2 MGI:MGI:2385618|Ensembl:ENSMUSG00000041445 +105452 AB039980 MGI:MGI:2145591 +105465 AI225892 MGI:MGI:2145604 +105501 Abhd4 MGI:MGI:1915938|Ensembl:ENSMUSG00000040997|Vega:OTTMUSG00000053873 +105504 Exoc5 MGI:MGI:2145645|Ensembl:ENSMUSG00000061244|Vega:OTTMUSG00000034599 +105511 Fam170b MGI:MGI:2145650|Ensembl:ENSMUSG00000078127 +105513 Chmp7 MGI:MGI:1913922|Ensembl:ENSMUSG00000034190 +105518 A630023A22Rik MGI:MGI:2145657|Ensembl:ENSMUSG00000095493|Vega:OTTMUSG00000063357 +105522 Ankrd28 MGI:MGI:2145661|Ensembl:ENSMUSG00000014496 +105525 AI480461 MGI:MGI:2145664 +105545 C130012C08Rik MGI:MGI:2145684 +105546 AI646531 MGI:MGI:2145685 +105559 Mbnl2 MGI:MGI:2145597|Ensembl:ENSMUSG00000022139 +105573 AI987986 MGI:MGI:2145712 +105590 Zfp957 MGI:MGI:2145729|Ensembl:ENSMUSG00000071262|Vega:OTTMUSG00000034684 +105592 AU018466 MGI:MGI:2145731 +105594 Cphx1 MGI:MGI:2145733|Ensembl:ENSMUSG00000095975|Vega:OTTMUSG00000044545 +105596 AU020094 MGI:MGI:2145735 +105600 D14Mgi24 MGI:MGI:2145739 +105601 AU021745 MGI:MGI:2145740 +105602 AU022240 MGI:MGI:2145741 +105604 AU022395 MGI:MGI:2145743 +105610 AU024086 MGI:MGI:2145749 +105611 AU040096 MGI:MGI:2145750 +105638 Dph3 MGI:MGI:1922658|Ensembl:ENSMUSG00000021905|Vega:OTTMUSG00000019770 +105651 Ppp1r3e MGI:MGI:2145790|Ensembl:ENSMUSG00000072494|Vega:OTTMUSG00000033368 +105653 Phyhip MGI:MGI:1860417|Ensembl:ENSMUSG00000003469|Vega:OTTMUSG00000034316 +105663 Thtpa MGI:MGI:2446078|Ensembl:ENSMUSG00000045691|Vega:OTTMUSG00000027954 +105670 Rcbtb2 MGI:MGI:1917200|Ensembl:ENSMUSG00000022106|Vega:OTTMUSG00000036135 +105675 Ppif MGI:MGI:2145814|Ensembl:ENSMUSG00000021868|Vega:OTTMUSG00000023363 +105689 Mycbp2 MGI:MGI:2179432|Ensembl:ENSMUSG00000033004|Vega:OTTMUSG00000034690 +105692 AW549269 MGI:MGI:2145831 +105707 BB055853 MGI:MGI:2145846 +105710 BB086117 MGI:MGI:2145849 +105718 BB176409 MGI:MGI:2145857 +105722 Ano6 MGI:MGI:2145890|Ensembl:ENSMUSG00000064210 +105727 Slc38a1 MGI:MGI:2145895|Ensembl:ENSMUSG00000023169 +105732 Fam83h MGI:MGI:2145900|Ensembl:ENSMUSG00000046761 +105734 Tigd5 MGI:MGI:2145902|Ensembl:ENSMUSG00000103906|Vega:OTTMUSG00000050036 +105740 AA511244 MGI:MGI:2145908 +105741 AA511283 MGI:MGI:2145909 +105742 AA516735 MGI:MGI:2145910 +105743 AA516936 MGI:MGI:2145911 +105744 AA516939 MGI:MGI:2145912 +105745 AA517542 MGI:MGI:2145913 +105746 AA517844 MGI:MGI:2145914 +105748 AA545189 MGI:MGI:2145916 +105755 AA589642 MGI:MGI:2145923 +105759 AA675007 MGI:MGI:2145927 +105763 AA960008 MGI:MGI:2145931 +105776 AI115024 MGI:MGI:2145944 +105782 Scrib MGI:MGI:2145950|Ensembl:ENSMUSG00000022568|Vega:OTTMUSG00000021033 +105785 Kdelr3 MGI:MGI:2145953|Ensembl:ENSMUSG00000010830 +105787 Prkaa1 MGI:MGI:2145955|Ensembl:ENSMUSG00000050697 +105798 AI256671 MGI:MGI:2145966 +105827 Amigo2 MGI:MGI:2145995|Ensembl:ENSMUSG00000048218 +105833 Ccdc65 MGI:MGI:2146001|Ensembl:ENSMUSG00000003354 +105835 Sgsm3 MGI:MGI:1916329|Ensembl:ENSMUSG00000042303|Vega:OTTMUSG00000034072 +105837 Mtbp MGI:MGI:2146005|Ensembl:ENSMUSG00000022369|Vega:OTTMUSG00000035624 +105841 Dennd3 MGI:MGI:2146009|Ensembl:ENSMUSG00000036661|Vega:OTTMUSG00000032985 +105843 AI448362 MGI:MGI:2146011 +105844 Card10 MGI:MGI:2146012|Ensembl:ENSMUSG00000033170|Vega:OTTMUSG00000035247 +105847 Lmf2 MGI:MGI:2146015|Ensembl:ENSMUSG00000022614 +105853 Mal2 MGI:MGI:2146021|Ensembl:ENSMUSG00000024479 +105855 Nckap1l MGI:MGI:1926063|Ensembl:ENSMUSG00000022488 +105859 Csdc2 MGI:MGI:2146027|Ensembl:ENSMUSG00000042109|Vega:OTTMUSG00000028156 +105860 AI503316 MGI:MGI:2146028 +105866 Krt72 MGI:MGI:2146034|Ensembl:ENSMUSG00000056605|Vega:OTTMUSG00000027998 +105868 AI528492 MGI:MGI:2146036 +105877 AI605151 MGI:MGI:2146045 +105887 Ugt3a1 MGI:MGI:2146055|Ensembl:ENSMUSG00000072664|Vega:OTTMUSG00000026414 +105892 9030619P08Rik MGI:MGI:3612405|Ensembl:ENSMUSG00000053168 +105894 AI790276 MGI:MGI:2146062 +105896 AI835086 MGI:MGI:2146064 +105932 AI931719 MGI:MGI:2146100 +105941 AL022815 MGI:MGI:2146109 +105956 AU015438 MGI:MGI:2146124 +105957 AU015449 MGI:MGI:2146125 +105964 AU019754 MGI:MGI:2146132 +105968 AU021063 MGI:MGI:2146136 +105969 AU021782 MGI:MGI:2146137 +105971 AU021833 MGI:MGI:2146139 +105972 AU021889 MGI:MGI:2146140 +105974 AU022749 MGI:MGI:2146142 +105975 AU022754 MGI:MGI:2146143|Ensembl:ENSMUSG00000097209 +105976 AU022793 MGI:MGI:2146144 +105977 AU022852 MGI:MGI:2146145 +105988 Espl1 MGI:MGI:2146156|Ensembl:ENSMUSG00000058290 +105989 AU045094 MGI:MGI:2146157 +105994 D15Mgi30 MGI:MGI:2146162 +106014 Fam19a5 MGI:MGI:2146182|Ensembl:ENSMUSG00000054863 +106017 AW050190 MGI:MGI:2146185 +106021 Topors MGI:MGI:2146189|Ensembl:ENSMUSG00000036822|Vega:OTTMUSG00000006555 +106025 Sharpin MGI:MGI:1913331|Ensembl:ENSMUSG00000022552|Vega:OTTMUSG00000023724 +106026 AW121686 MGI:MGI:2146194 +106039 Gga1 MGI:MGI:2146207|Ensembl:ENSMUSG00000033128 +106042 Prickle1 MGI:MGI:1916034|Ensembl:ENSMUSG00000036158|Vega:OTTMUSG00000021009 +106046 AW413774 MGI:MGI:2146214 +106052 Fbxo4 MGI:MGI:2146220|Ensembl:ENSMUSG00000022184|Vega:OTTMUSG00000027965 +106059 A430088P11Rik MGI:MGI:3605804 +106064 AW549877 MGI:MGI:2146232|Ensembl:ENSMUSG00000041935 +106068 Slc45a4 MGI:MGI:2146236|Ensembl:ENSMUSG00000079020|Vega:OTTMUSG00000032799 +106073 Mfsd5 MGI:MGI:2145901|Ensembl:ENSMUSG00000045665 +106074 AW557046 MGI:MGI:2146242 +106079 AW742793 MGI:MGI:2146247 +106080 AW742948 MGI:MGI:2146248 +106088 BB060269 MGI:MGI:2146256 +106096 BB157357 MGI:MGI:2146264 +106097 D15Mgi29 MGI:MGI:2146265 +106121 AA516830 MGI:MGI:2146348 +106125 AA537038 MGI:MGI:2146352 +106126 AA537047 MGI:MGI:2146353 +106131 AA589532 MGI:MGI:2146358 +106137 D16Mgi22 MGI:MGI:2146364 +106143 Cggbp1 MGI:MGI:2146370|Ensembl:ENSMUSG00000054604|Vega:OTTMUSG00000026276 +106150 AI115486 MGI:MGI:2146377 +106162 AI197313 MGI:MGI:2146389 +106170 D630050H08Rik MGI:MGI:2146397 +106185 AI324963 MGI:MGI:2146412 +106200 Txndc11 MGI:MGI:1923620|Ensembl:ENSMUSG00000022498|Vega:OTTMUSG00000026399 +106201 AI428301 MGI:MGI:2146428 +106205 Zc3h7a MGI:MGI:2445044|Ensembl:ENSMUSG00000037965|Vega:OTTMUSG00000026400 +106226 AI528516 MGI:MGI:2146453 +106248 Qtrt2 MGI:MGI:1922194|Ensembl:ENSMUSG00000022704|Vega:OTTMUSG00000026821 +106250 AI662175 MGI:MGI:2146477 +106251 D230034L24Rik MGI:MGI:2146478 +106258 AI790442 MGI:MGI:2146485 +106264 0610012G03Rik MGI:MGI:1913301|Ensembl:ENSMUSG00000107002|Vega:OTTMUSG00000056269 +106267 AI844685 MGI:MGI:2146494 +106274 AI848615 MGI:MGI:2146501 +106286 D16Mgi11 MGI:MGI:2146513 +106296 AL022871 MGI:MGI:2146523 +106298 Rrn3 MGI:MGI:1925255|Ensembl:ENSMUSG00000022682 +106299 AL023045 MGI:MGI:2146526 +106306 AU014876 MGI:MGI:2146533 +106309 AU015336 MGI:MGI:2146536 +106313 AU015734 MGI:MGI:2146540 +106315 AU015849 MGI:MGI:2146542 +106316 AU015881 MGI:MGI:2146543 +106321 AU017796 MGI:MGI:2146548 +106326 Osbpl11 MGI:MGI:2146553|Ensembl:ENSMUSG00000022807|Vega:OTTMUSG00000024261 +106334 AU021880 MGI:MGI:2146561 +106335 AU021884 MGI:MGI:2146562 +106336 AU022167 MGI:MGI:2146563 +106337 AU022434 MGI:MGI:2146564 +106338 Nsun3 MGI:MGI:2146565|Ensembl:ENSMUSG00000050312|Vega:OTTMUSG00000024099 +106341 AU022867 MGI:MGI:2146568 +106344 Rfc4 MGI:MGI:2146571|Ensembl:ENSMUSG00000022881|Vega:OTTMUSG00000025290 +106347 Ildr1 MGI:MGI:2146574|Ensembl:ENSMUSG00000022900|Vega:OTTMUSG00000014981 +106369 Ypel1 MGI:MGI:1913303|Ensembl:ENSMUSG00000022773|Vega:OTTMUSG00000023943 +106373 AV205837 MGI:MGI:2146600 +106389 Eaf2 MGI:MGI:2146616|Ensembl:ENSMUSG00000022838|Vega:OTTMUSG00000024641 +106391 AW107722 MGI:MGI:2146618 +106393 Srl MGI:MGI:2146620|Ensembl:ENSMUSG00000022519|Vega:OTTMUSG00000026711 +106407 Slc51a MGI:MGI:2146634|Ensembl:ENSMUSG00000035699|Vega:OTTMUSG00000025790 +106445 AW742604 MGI:MGI:2146672 +106450 D16Mgi32 MGI:MGI:2146677 +106459 BB163080 MGI:MGI:2146686 +106484 AA409289 MGI:MGI:2146757 +106489 Sft2d1 MGI:MGI:1918689|Ensembl:ENSMUSG00000073468|Vega:OTTMUSG00000033022 +106493 AA415437 MGI:MGI:2146766 +106494 D17Mgi15 MGI:MGI:2146767 +106495 AA516613 MGI:MGI:2146768 +106496 AA517668 MGI:MGI:2146769 +106497 AA517669 MGI:MGI:2146770 +106498 AA517753 MGI:MGI:2146771 +106504 Stk38 MGI:MGI:2442572|Ensembl:ENSMUSG00000024006|Vega:OTTMUSG00000031637 +106506 AA673181 MGI:MGI:2146779 +106512 Gpsm3 MGI:MGI:2146785|Ensembl:ENSMUSG00000034786|Vega:OTTMUSG00000020244 +106522 Pkdcc MGI:MGI:2147077|Ensembl:ENSMUSG00000024247|Vega:OTTMUSG00000035220 +106527 AI131754 MGI:MGI:2146800 +106529 Tecr MGI:MGI:1915408|Ensembl:ENSMUSG00000031708|Vega:OTTMUSG00000061574 +106549 AI317158 MGI:MGI:2146822 +106557 Ldhal6b MGI:MGI:2146830|Ensembl:ENSMUSG00000101959|Vega:OTTMUSG00000045083 +106564 Ppcs MGI:MGI:1915237|Ensembl:ENSMUSG00000028636|Vega:OTTMUSG00000009426 +106565 Dlk2 MGI:MGI:2146838|Ensembl:ENSMUSG00000047428|Vega:OTTMUSG00000036095 +106572 Rab31 MGI:MGI:1914603|Ensembl:ENSMUSG00000056515 +106581 Fam234a MGI:MGI:2146854|Ensembl:ENSMUSG00000024187|Vega:OTTMUSG00000026503 +106582 Nrm MGI:MGI:2146855|Ensembl:ENSMUSG00000059791|Vega:OTTMUSG00000037408 +106583 Scaf8 MGI:MGI:1925212|Ensembl:ENSMUSG00000046201 +106585 Ankrd12 MGI:MGI:1914357|Ensembl:ENSMUSG00000034647|Vega:OTTMUSG00000023748 +106602 AI463580 MGI:MGI:2146875 +106604 AI467299 MGI:MGI:2146877 +106610 AI504002 MGI:MGI:2146883 +106618 Wdr90 MGI:MGI:1921267|Ensembl:ENSMUSG00000073434|Vega:OTTMUSG00000042163 +106619 AI553519 MGI:MGI:2146892 +106622 AI605517 MGI:MGI:2146895 +106626 AI645535 MGI:MGI:2146899 +106627 AI646383 MGI:MGI:2146900 +106628 Trip10 MGI:MGI:2146901|Ensembl:ENSMUSG00000019487 +106629 AI647874 MGI:MGI:2146902 +106633 Ift140 MGI:MGI:2146906|Ensembl:ENSMUSG00000024169|Vega:OTTMUSG00000024886 +106634 AI661323 MGI:MGI:2146907 +106639 Vmac MGI:MGI:2146912|Ensembl:ENSMUSG00000054723 +106648 Cyp4f15 MGI:MGI:2146921|Ensembl:ENSMUSG00000073424|Vega:OTTMUSG00000035749 +106672 AI413582 MGI:MGI:2146839|Ensembl:ENSMUSG00000062753|Vega:OTTMUSG00000028934 +106695 AU015230 MGI:MGI:2146968 +106704 AU018902 MGI:MGI:2146977 +106707 Rpusd1 MGI:MGI:1919186|Ensembl:ENSMUSG00000041199 +106717 AU021760 MGI:MGI:2146990 +106718 AU022096 MGI:MGI:2146991 +106719 AU022490 MGI:MGI:2146992 +106722 G6b MGI:MGI:2146995|Ensembl:ENSMUSG00000073414|Vega:OTTMUSG00000014959 +106725 AU041480 MGI:MGI:2146998 +106740 LOC106740 - +106757 Catsperd MGI:MGI:2147030|Ensembl:ENSMUSG00000040828 +106759 Ticam1 MGI:MGI:2147032|Ensembl:ENSMUSG00000047123|Vega:OTTMUSG00000016637 +106762 AW047481 MGI:MGI:2147035 +106763 Ttbk1 MGI:MGI:2147036|Ensembl:ENSMUSG00000015599 +106766 Stap2 MGI:MGI:2147039|Ensembl:ENSMUSG00000038781 +106794 Dhx57 MGI:MGI:2147067|Ensembl:ENSMUSG00000035051 +106795 Tcf19 MGI:MGI:103180|Ensembl:ENSMUSG00000050410|Vega:OTTMUSG00000034281 +106817 AW556556 MGI:MGI:2147090 +106821 Oard1 MGI:MGI:2146818|Ensembl:ENSMUSG00000040771 +106823 D930007N19Rik MGI:MGI:2147096 +106824 D230046O15Rik MGI:MGI:2147097 +106828 AW743368 MGI:MGI:2147101 +106829 AW743439 MGI:MGI:2147102 +106838 BB217838 MGI:MGI:2147111 +106839 AA407331 MGI:MGI:2147161 +106840 Unc119b MGI:MGI:2147162|Ensembl:ENSMUSG00000046562|Vega:OTTMUSG00000014628 +106842 AA407787 MGI:MGI:2147164 +106846 AA408650 MGI:MGI:2147168 +106851 AA516602 MGI:MGI:2147173 +106852 AA516741 MGI:MGI:2147174 +106854 AA517638 MGI:MGI:2147176 +106856 AA522005 MGI:MGI:2147178 +106861 Abhd3 MGI:MGI:2147183|Ensembl:ENSMUSG00000002475|Vega:OTTMUSG00000028162 +106862 AA763521 MGI:MGI:2147184 +106869 Tnfaip8 MGI:MGI:2147191|Ensembl:ENSMUSG00000062210|Vega:OTTMUSG00000033192 +106875 AI115542 MGI:MGI:2147197 +106877 Afap1l1 MGI:MGI:2147199|Ensembl:ENSMUSG00000033032|Vega:OTTMUSG00000029961 +106878 Smim3 MGI:MGI:1917088|Ensembl:ENSMUSG00000038059 +106885 AI314760 MGI:MGI:2147207 +106894 Hmgxb3 MGI:MGI:2441817|Ensembl:ENSMUSG00000024622 +106906 AI450241 MGI:MGI:2147228 +106907 AI450907 MGI:MGI:2147229 +106930 AI661384 MGI:MGI:2147252 +106931 Kctd1 MGI:MGI:1918269|Ensembl:ENSMUSG00000036225 +106935 AI664001 MGI:MGI:2147257 +106947 Slc39a3 MGI:MGI:2147269|Ensembl:ENSMUSG00000046822|Vega:OTTMUSG00000030300 +106952 Arap3 MGI:MGI:2147274|Ensembl:ENSMUSG00000024451 +106954 AI851613 MGI:MGI:2147276 +106957 Slc39a6 MGI:MGI:2147279|Ensembl:ENSMUSG00000024270|Vega:OTTMUSG00000033982 +106964 AL022850 MGI:MGI:2147286 +106967 4732423E21Rik MGI:MGI:2147289 +106969 AU014988 MGI:MGI:2147291 +106970 AU015140 MGI:MGI:2147292 +106972 AU015601 MGI:MGI:2147294 +106973 AU015741 MGI:MGI:2147295 +106974 AU015858 MGI:MGI:2147296 +106980 AU018705 MGI:MGI:2147302 +106981 AU018728 MGI:MGI:2147303 +106982 AU018823 MGI:MGI:2147304 +106986 AU020951 MGI:MGI:2147308 +106988 AU022049 MGI:MGI:2147310 +106989 AU022136 MGI:MGI:2147311 +106990 AU022178 MGI:MGI:2147312 +106993 AU022538 MGI:MGI:2147315 +107003 A330093E20Rik MGI:MGI:2147325 +107018 AW046287 MGI:MGI:2147340 +107022 Gramd3 MGI:MGI:1914815|Ensembl:ENSMUSG00000001700 +107029 Me2 MGI:MGI:2147351|Ensembl:ENSMUSG00000024556 +107035 Fbxo38 MGI:MGI:2444639|Ensembl:ENSMUSG00000042211 +107045 Lars MGI:MGI:1913808|Ensembl:ENSMUSG00000024493 +107047 Psmg2 MGI:MGI:1922901|Ensembl:ENSMUSG00000024537 +107056 AW742475 MGI:MGI:2147378 +107064 BB125182 MGI:MGI:2147386 +107065 Lrrtm2 MGI:MGI:2389174|Ensembl:ENSMUSG00000071862 +107071 Wdr74 MGI:MGI:2147427|Ensembl:ENSMUSG00000042729|Ensembl:ENSMUSG00000110423|Vega:OTTMUSG00000060351|Vega:OTTMUSG00000060352 +107086 AA409025 MGI:MGI:2147442 +107089 AA416451 MGI:MGI:2147445 +107091 AA517132 MGI:MGI:2147447 +107094 Rrp12 MGI:MGI:2147437|Ensembl:ENSMUSG00000035049 +107131 AI195470 MGI:MGI:2147487 +107141 Cyp2c50 MGI:MGI:2147497|Ensembl:ENSMUSG00000054827|Vega:OTTMUSG00000028293 +107142 AI266966 MGI:MGI:2147498 +107143 AI314034 MGI:MGI:2147499 +107146 Glyat MGI:MGI:2147502|Ensembl:ENSMUSG00000063683|Vega:OTTMUSG00000028283 +107150 AI317275 MGI:MGI:2147506 +107157 AI327134 MGI:MGI:2147513 +107166 AI415730 MGI:MGI:2147522 +107171 AI428314 MGI:MGI:2147527 +107173 Gpr137 MGI:MGI:2147529|Ensembl:ENSMUSG00000024958 +107182 Btaf1 MGI:MGI:2147538|Ensembl:ENSMUSG00000040565|Vega:OTTMUSG00000042429 +107197 Uqcc3 MGI:MGI:2147553|Ensembl:ENSMUSG00000071654 +107221 Ffar4 MGI:MGI:2147577|Ensembl:ENSMUSG00000054200 +107227 Macrod1 MGI:MGI:2147583|Ensembl:ENSMUSG00000036278 +107239 Carns1 MGI:MGI:2147595|Ensembl:ENSMUSG00000075289 +107242 AI837181 MGI:MGI:2147598|Ensembl:ENSMUSG00000047423|Vega:OTTMUSG00000034961 +107250 Kazald1 MGI:MGI:2147606|Ensembl:ENSMUSG00000025213|Vega:OTTMUSG00000014896 +107252 AI843588 MGI:MGI:2147608 +107260 Otub1 MGI:MGI:2147616|Ensembl:ENSMUSG00000024767|Vega:OTTMUSG00000033932 +107271 Yars MGI:MGI:2147627|Ensembl:ENSMUSG00000028811|Vega:OTTMUSG00000009617 +107272 Psat1 MGI:MGI:2183441|Ensembl:ENSMUSG00000024640|Vega:OTTMUSG00000030919 +107279 AU014972 MGI:MGI:2147635 +107282 1110034N17Rik MGI:MGI:2147638 +107291 AU021773 MGI:MGI:2147647 +107292 AU021789 MGI:MGI:2147648 +107294 AU022848 MGI:MGI:2147650 +107295 AU022855 MGI:MGI:2147651 +107296 AU022933 MGI:MGI:2147652 +107305 Vps37c MGI:MGI:2147661|Ensembl:ENSMUSG00000048832 +107306 AU042950 MGI:MGI:2147662 +107321 Lpxn MGI:MGI:2147677|Ensembl:ENSMUSG00000024696 +107324 AV313155 MGI:MGI:2147680 +107328 Trpt1 MGI:MGI:1333115|Ensembl:ENSMUSG00000047656 +107338 Gbf1 MGI:MGI:1861607|Ensembl:ENSMUSG00000025224|Vega:OTTMUSG00000040139 +107350 AW112010 MGI:MGI:2147706|Ensembl:ENSMUSG00000075010 +107351 Kank1 MGI:MGI:2147707|Ensembl:ENSMUSG00000032702|Vega:OTTMUSG00000033447 +107358 Tm9sf3 MGI:MGI:1914262|Ensembl:ENSMUSG00000025016 +107368 Pdzd8 MGI:MGI:2677270|Ensembl:ENSMUSG00000074746 +107371 Exoc6 MGI:MGI:1351611|Ensembl:ENSMUSG00000053799 +107372 C030016D13Rik MGI:MGI:2147728 +107373 Fam111a MGI:MGI:1915508|Ensembl:ENSMUSG00000024691|Vega:OTTMUSG00000033033 +107375 Slc25a45 MGI:MGI:2147731|Ensembl:ENSMUSG00000024818|Vega:OTTMUSG00000033082 +107376 E330013P04Rik MGI:MGI:2147732|Ensembl:ENSMUSG00000053117 +107377 AW492981 MGI:MGI:2147733 +107392 Brms1 MGI:MGI:2388804|Ensembl:ENSMUSG00000080268 +107400 AW742565 MGI:MGI:2147756 +107401 AW742912 MGI:MGI:2147757 +107402 AW742986 MGI:MGI:2147758 +107404 AW743299 MGI:MGI:2147760 +107412 BB143722 MGI:MGI:2147768 +107416 BB164765 MGI:MGI:2147772 +107417 Aap MGI:MGI:87856 +107418 Bas MGI:MGI:88130 +107419 Das MGI:MGI:94861 +107421 Idc MGI:MGI:96399 +107422 Prid1 MGI:MGI:97582 +107423 Tag MGI:MGI:98478 +107424 Ylr MGI:MGI:99148 +107425 Gcna MGI:MGI:105113 +107431 Gpr31 MGI:MGI:1354379 +107433 Gsh5 MGI:MGI:95845 +107435 Hat1 MGI:MGI:96013|Ensembl:ENSMUSG00000027018|Vega:OTTMUSG00000013187 +107436 Pchr MGI:MGI:102624 +107438 Cinda1 MGI:MGI:1096555 +107442 Sipd1 MGI:MGI:1298394 +107447 Bgb MGI:MGI:88150 +107448 Unc5a MGI:MGI:894682|Ensembl:ENSMUSG00000025876|Vega:OTTMUSG00000032671 +107449 Unc5b MGI:MGI:894703|Ensembl:ENSMUSG00000020099 +107450 Fv3 MGI:MGI:95597 +107451 Fv6 MGI:MGI:95600 +107452 Hld MGI:MGI:96107 +107453 Rasl2-6 MGI:MGI:97867 +107454 Rasl5-1 MGI:MGI:97871 +107460 Rdh2 MGI:MGI:1201385 +107462 Aia2 MGI:MGI:87974 +107463 Cpl1 MGI:MGI:88483 +107464 Cpl2 MGI:MGI:88484 +107465 Exz2 MGI:MGI:95469 +107466 Pcas MGI:MGI:97498 +107467 Pcts MGI:MGI:97519 +107468 Rim5 MGI:MGI:97927 +107469 Nba1 MGI:MGI:101767 +107476 Acaca MGI:MGI:108451|Ensembl:ENSMUSG00000020532|Vega:OTTMUSG00000000985 +107477 Guca1b MGI:MGI:1194489|Ensembl:ENSMUSG00000023979|Vega:OTTMUSG00000031580 +107478 Emv69 MGI:MGI:1858217 +107479 Emv71 MGI:MGI:1858218 +107480 Emv70 MGI:MGI:1858276 +107481 Tgct1 MGI:MGI:1891251 +107482 Ack MGI:MGI:87877 +107483 Av1 MGI:MGI:88119 +107484 Av2 MGI:MGI:88120 +107485 Cle MGI:MGI:88419 +107487 Lus MGI:MGI:96852 +107488 Tel1q MGI:MGI:98686 +107489 Tel3q MGI:MGI:98690 +107490 Tel5q MGI:MGI:98694 +107491 Tel6q MGI:MGI:98696 +107492 Tel7q MGI:MGI:98698 +107493 Tel8q MGI:MGI:98700 +107494 Scfr3 MGI:MGI:1096862 +107502 Mnp MGI:MGI:1352509 +107503 Atf5 MGI:MGI:2141857|Ensembl:ENSMUSG00000038539|Vega:OTTMUSG00000021114 +107505 Neurod5 MGI:MGI:893590 +107506 Ldr2 MGI:MGI:96767 +107507 Pcs1 MGI:MGI:97510 +107508 Eprs MGI:MGI:97838|Ensembl:ENSMUSG00000026615|Vega:OTTMUSG00000050732 +107509 Sdr1 MGI:MGI:98268 +107510 Sdr2 MGI:MGI:98269 +107511 Sto1 MGI:MGI:98435 +107512 Sto2 MGI:MGI:98436 +107513 Ssr1 MGI:MGI:105082|Ensembl:ENSMUSG00000021427 +107515 Lgr4 MGI:MGI:1891468|Ensembl:ENSMUSG00000050199|Vega:OTTMUSG00000015138 +107521 Bis2 MGI:MGI:104784 +107522 Ece2 MGI:MGI:1101356|Ensembl:ENSMUSG00000022842|Vega:OTTMUSG00000028772 +107526 Gimap4 MGI:MGI:1349656|Ensembl:ENSMUSG00000054435|Vega:OTTMUSG00000026892 +107527 Il1rl2 MGI:MGI:1913107|Ensembl:ENSMUSG00000070942|Vega:OTTMUSG00000050520 +107528 Magee1 MGI:MGI:2148149|Ensembl:ENSMUSG00000031227|Vega:OTTMUSG00000018098 +107533 Mageb9 MGI:MGI:2148173 +107534 Bkm2 MGI:MGI:88162 +107535 Bkm3 MGI:MGI:88163 +107536 Bkm5 MGI:MGI:88165 +107537 Ihe1 MGI:MGI:96532 +107538 Int53 MGI:MGI:96578 +107539 Lap2 MGI:MGI:96750 +107540 Rhv1 MGI:MGI:97915 +107541 Rhv2 MGI:MGI:97916 +107542 Tsve1 MGI:MGI:98861 +107547 Bkm4 MGI:MGI:88164 +107548 Bkm6 MGI:MGI:88166 +107549 Mlvi3 MGI:MGI:97002 +107550 Tel10q MGI:MGI:98666 +107551 Tel11q MGI:MGI:98668 +107552 Tel12q MGI:MGI:98670 +107553 Tel15q MGI:MGI:98676 +107554 Tel18q MGI:MGI:98682 +107555 Tel19q MGI:MGI:98684 +107556 Msbp1 MGI:MGI:102767 +107557 Scfr2 MGI:MGI:106090 +107560 Man1b-rs MGI:MGI:109556 +107566 Arl2bp MGI:MGI:1349429|Ensembl:ENSMUSG00000031776|Vega:OTTMUSG00000061690 +107568 Wwp1 MGI:MGI:1861728|Ensembl:ENSMUSG00000041058|Vega:OTTMUSG00000006367 +107569 Nt5c3 MGI:MGI:1927186|Ensembl:ENSMUSG00000029780|Vega:OTTMUSG00000023209 +107570 Anth MGI:MGI:88027 +107572 Mchm2 MGI:MGI:96936 +107573 Tcrg-C1 MGI:MGI:98625|IMGT/GENE-DB:TRGC1 +107574 Tcrg-C2 MGI:MGI:98626|IMGT/GENE-DB:TRGC2 +107575 Tcrg-C3 MGI:MGI:98627|IMGT/GENE-DB:TRGC3 +107576 Tcrg-C4 MGI:MGI:98628|IMGT/GENE-DB:TRGC4 +107577 Inf1 MGI:MGI:99840 +107579 Nr1d2-rs1 MGI:MGI:106678 +107580 Nr1d2-rs2 MGI:MGI:106681 +107581 Col16a1 MGI:MGI:1095396|Ensembl:ENSMUSG00000040690|Vega:OTTMUSG00000009516 +107585 Dio3 MGI:MGI:1306782|Ensembl:ENSMUSG00000075707|Vega:OTTMUSG00000038181 +107586 Ovol2 MGI:MGI:1338039|Ensembl:ENSMUSG00000037279|Vega:OTTMUSG00000003483 +107587 Osr2 MGI:MGI:1930813|Ensembl:ENSMUSG00000022330 +107589 Mylk MGI:MGI:894806|Ensembl:ENSMUSG00000022836|Vega:OTTMUSG00000017049 +107590 If3 MGI:MGI:96422 +107591 If4 MGI:MGI:96423 +107598 Nhcp7 MGI:MGI:97338 +107601 Ts3 MGI:MGI:98843 +107602 Ts4 MGI:MGI:98844 +107603 Raet8 MGI:MGI:103246 +107604 Spi5l MGI:MGI:103558 +107605 Rdh1 MGI:MGI:1195275|Ensembl:ENSMUSG00000089789|Vega:OTTMUSG00000027662 +107607 Nod1 MGI:MGI:1341839|Ensembl:ENSMUSG00000038058|Vega:OTTMUSG00000057766 +107608 Tcrd-V8 MGI:MGI:1927088 +107613 Lblr MGI:MGI:96752 +107620 Evi10 MGI:MGI:106193 +107623 Pgame1 MGI:MGI:1202068 +107624 C6r MGI:MGI:88234 +107626 Asmt MGI:MGI:96090|Ensembl:ENSMUSG00000093806 +107627 If2 MGI:MGI:96421 +107632 Zfp211 MGI:MGI:109616 +107650 Pi4kb MGI:MGI:1334433|Ensembl:ENSMUSG00000038861|Vega:OTTMUSG00000019669 +107652 Uap1 MGI:MGI:1334459|Ensembl:ENSMUSG00000026670|Vega:OTTMUSG00000023030 +107656 Krt9 MGI:MGI:96696|Ensembl:ENSMUSG00000051617|Vega:OTTMUSG00000002544 +107671 Ilk-rs MGI:MGI:1195465 +107676 Air1 MGI:MGI:87975 +107683 Tria3 MGI:MGI:1339989 +107684 Coro2a MGI:MGI:1345966|Ensembl:ENSMUSG00000028337|Vega:OTTMUSG00000006922 +107685 Carg2 MGI:MGI:894647 +107686 Snrpd2 MGI:MGI:98345|Ensembl:ENSMUSG00000040824|Vega:OTTMUSG00000029193 +107687 Tmtr MGI:MGI:98777 +107688 Inf2q MGI:MGI:99839 +107689 Pet1 MGI:MGI:102766 +107690 Tse4 MGI:MGI:102777 +107691 Tcrg-V1.2 MGI:MGI:104909 +107692 Tcrg-V1.1 MGI:MGI:104910 +107693 Hfm MGI:MGI:105953 +107694 Actn2-rs1 MGI:MGI:109193 +107696 Capop MGI:MGI:1890950 +107697 Tcrg-J MGI:MGI:98629 +107698 Tim MGI:MGI:98751 +107701 Sf3b4 MGI:MGI:109580|Ensembl:ENSMUSG00000068856|Vega:OTTMUSG00000021896 +107702 Rnh1 MGI:MGI:1195456|Ensembl:ENSMUSG00000038650|Vega:OTTMUSG00000060389 +107708 Prdx2-rs6 MGI:MGI:1859811 +107710 Aem1 MGI:MGI:87950 +107711 Tcrbe MGI:MGI:892967 +107712 Rcs1 MGI:MGI:97882 +107713 Ptma-rs3 MGI:MGI:107631 +107714 Ptma-rs1 MGI:MGI:107632 +107721 Evi30 MGI:MGI:1355290 +107723 Slc12a6 MGI:MGI:2135960|Ensembl:ENSMUSG00000027130|Ensembl:ENSMUSG00000096764|Vega:OTTMUSG00000015141|Vega:OTTMUSG00000042283 +107725 Rv2 MGI:MGI:98210 +107726 Rv3 MGI:MGI:98211 +107727 Tcrg-V MGI:MGI:98630 +107728 Tcrd-V MGI:MGI:104914 +107729 Ubg MGI:MGI:106200 +107730 Tpd52-ps MGI:MGI:107737 +107732 Mrpl10 MGI:MGI:1333801|Ensembl:ENSMUSG00000001445|Vega:OTTMUSG00000002231 +107733 Mrpl41 MGI:MGI:1333816|Ensembl:ENSMUSG00000036850|Vega:OTTMUSG00000011562 +107734 Mrpl30 MGI:MGI:1333820|Ensembl:ENSMUSG00000026087|Vega:OTTMUSG00000026562 +107739 Adre MGI:MGI:87942 +107741 Ril2 MGI:MGI:97923 +107742 Tse3 MGI:MGI:98846 +107746 Rapgef1 MGI:MGI:104580|Ensembl:ENSMUSG00000039844|Vega:OTTMUSG00000012043 +107747 Aldh1l1 MGI:MGI:1340024|Ensembl:ENSMUSG00000030088|Vega:OTTMUSG00000025984 +107749 Zfp122-rs MGI:MGI:1858461 +107751 Prrxl1 MGI:MGI:2148204|Ensembl:ENSMUSG00000041730|Vega:OTTMUSG00000045726 +107753 Lgals2 MGI:MGI:895068|Ensembl:ENSMUSG00000043501 +107754 Dipl1 MGI:MGI:94897 +107755 Hv1 MGI:MGI:96288 +107756 Pscr1 MGI:MGI:97784 +107757 Pscr2 MGI:MGI:97785 +107758 Ril1 MGI:MGI:97922 +107759 Tcra-V16.1 MGI:MGI:106216 +107765 Ankrd1 MGI:MGI:1097717|Ensembl:ENSMUSG00000024803 +107766 Haao MGI:MGI:1349444|Ensembl:ENSMUSG00000000673 +107767 Scamp1 MGI:MGI:1349480|Ensembl:ENSMUSG00000021687|Vega:OTTMUSG00000033839 +107768 Birc5l MGI:MGI:1933149 +107769 Tm6sf1 MGI:MGI:1933209|Ensembl:ENSMUSG00000038623|Vega:OTTMUSG00000024529 +107770 Tm6sf2 MGI:MGI:1933210|Ensembl:ENSMUSG00000036151|Vega:OTTMUSG00000027309 +107771 Bmyc MGI:MGI:88184|Ensembl:ENSMUSG00000049086|Vega:OTTMUSG00000012633 +107772 Mclr MGI:MGI:96934 +107773 Melb MGI:MGI:96961 +107774 Tse2 MGI:MGI:98845 +107780 Cd79bl-rs4 MGI:MGI:1309491 +107785 Alm MGI:MGI:87996 +107786 Bmfr2 MGI:MGI:88173 +107787 Msz MGI:MGI:97170 +107788 Tel1p MGI:MGI:98685 +107789 Tel3p MGI:MGI:98689 +107790 Tel4p MGI:MGI:98691 +107791 Tel5p MGI:MGI:98693 +107792 Tel6p MGI:MGI:98695 +107793 Tel8p MGI:MGI:98699 +107794 Tel9p MGI:MGI:98701 +107795 TelXp MGI:MGI:98703 +107802 Etet1 MGI:MGI:892976 +107803 Pick2 MGI:MGI:894655 +107804 Pick4 MGI:MGI:894660 +107805 Pick5 MGI:MGI:894661 +107806 Pick3 MGI:MGI:894665 +107810 Pscs MGI:MGI:97786 +107812 Tel5q1 MGI:MGI:107209 +107813 Tel3q1 MGI:MGI:107211 +107815 Scml2 MGI:MGI:1340042|Ensembl:ENSMUSG00000000037|Vega:OTTMUSG00000019586 +107817 Jmjd6 MGI:MGI:1858910|Ensembl:ENSMUSG00000056962|Vega:OTTMUSG00000003777 +107818 Myhn3 MGI:MGI:97259 +107819 Myhn4 MGI:MGI:97260 +107823 Nsd2 MGI:MGI:1276574|Ensembl:ENSMUSG00000057406|Vega:OTTMUSG00000025044 +107828 Tcra-V11.8 MGI:MGI:1341143 +107829 Thoc5 MGI:MGI:1351333|Ensembl:ENSMUSG00000034274|Vega:OTTMUSG00000005077 +107831 Adgrb1 MGI:MGI:1933736|Ensembl:ENSMUSG00000034730|Vega:OTTMUSG00000045270 +107833 Cdc2b MGI:MGI:88352 +107835 Idd6 MGI:MGI:96408 +107838 Nol1-rs MGI:MGI:107827 +107843 Trex2c MGI:MGI:1354368 +107844 Trex1c MGI:MGI:1354369 +107845 Trex1a MGI:MGI:1354375 +107846 Trex1b MGI:MGI:1354376 +107847 Trex2a MGI:MGI:1354382 +107848 Trex2b MGI:MGI:1354384 +107849 Prl2c5 MGI:MGI:1858413|Ensembl:ENSMUSG00000055360|Vega:OTTMUSG00000027712 +107851 Ifx MGI:MGI:96430 +107853 Scl1 MGI:MGI:98243 +107854 Tel10p MGI:MGI:98665 +107855 Tel11p MGI:MGI:98667 +107856 Tel12p MGI:MGI:98669 +107857 Tel15p MGI:MGI:98675 +107858 Tel18p MGI:MGI:98681 +107859 Tel19p MGI:MGI:98683 +107861 Shbdp1 MGI:MGI:1333835 +107864 Jevr MGI:MGI:96637 +107866 Tg.Myc MGI:MGI:98720 +107867 Tel12q1 MGI:MGI:107198 +107868 Usp9y MGI:MGI:1313274|Ensembl:ENSMUSG00000069044|Vega:OTTMUSG00000026255 +107869 Cth MGI:MGI:1339968|Ensembl:ENSMUSG00000028179|Vega:OTTMUSG00000029713 +107872 Idd15 MGI:MGI:99417 +107884 Idd14 MGI:MGI:99416 +107885 Mthfs MGI:MGI:1340032|Ensembl:ENSMUSG00000066442|Vega:OTTMUSG00000031930 +107888 Pbr MGI:MGI:97494 +107889 Gcm2 MGI:MGI:1861438|Ensembl:ENSMUSG00000021362 +107894 Minute MGI:MGI:1927811 +107895 Mgat5 MGI:MGI:894701|Ensembl:ENSMUSG00000036155|Vega:OTTMUSG00000049295 +107924 Ema MGI:MGI:95320 +107925 Gdcr1 MGI:MGI:95681 +107926 Gdcr2 MGI:MGI:95682 +107927 Htr1e MGI:MGI:96279 +107928 Hykk2 MGI:MGI:96304 +107932 Chd4 MGI:MGI:1344380|Ensembl:ENSMUSG00000063870|Vega:OTTMUSG00000023920 +107934 Celsr3 MGI:MGI:1858236|Ensembl:ENSMUSG00000023473|Vega:OTTMUSG00000050676 +107935 Idd9.1 MGI:MGI:1890082 +107936 Idd9.2 MGI:MGI:1890083 +107937 Idd9.3 MGI:MGI:1890084 +107939 Pom121 MGI:MGI:2137624|Ensembl:ENSMUSG00000053293|Vega:OTTMUSG00000024366 +107944 Yaa MGI:MGI:99140 +107945 Defa-rs9 MGI:MGI:102507 +107946 Defa-rs8 MGI:MGI:102508 +107947 Defa-rs6 MGI:MGI:102510 +107948 Defa-rs5 MGI:MGI:102511 +107949 H2-T5l MGI:MGI:1097703 +107951 Cdk9 MGI:MGI:1328368|Ensembl:ENSMUSG00000009555|Vega:OTTMUSG00000012534 +107954 Pim1-rs1 MGI:MGI:97585 +107960 Hp1bp1 MGI:MGI:109371 +107964 Pim1-rs2 MGI:MGI:97586 +107970 Hist1h1t MGI:MGI:1888530|Ensembl:ENSMUSG00000036211|Vega:OTTMUSG00000000557 +107971 Frs3 MGI:MGI:2135965|Ensembl:ENSMUSG00000023266|Vega:OTTMUSG00000018351 +107972 Defa-rs11 MGI:MGI:102515 +107973 H2-T13l MGI:MGI:1097707 +107974 H2-T23l MGI:MGI:1097715 +107975 Pacs1 MGI:MGI:1277113|Ensembl:ENSMUSG00000024855 +107976 Babam2 MGI:MGI:1333875|Ensembl:ENSMUSG00000052139|Vega:OTTMUSG00000023678 +107981 Amh-rs3 MGI:MGI:88009 +107982 Amh-rs5 MGI:MGI:88011 +107983 Amh-rs6 MGI:MGI:88012 +107984 Amh-rs8 MGI:MGI:88014 +107986 Ddb2 MGI:MGI:1355314|Ensembl:ENSMUSG00000002109|Vega:OTTMUSG00000014414 +107993 Bfsp2 MGI:MGI:1333828|Ensembl:ENSMUSG00000032556|Vega:OTTMUSG00000032745 +107994 Nidd4n MGI:MGI:1355302 +107995 Cdc20 MGI:MGI:1859866|Ensembl:ENSMUSG00000006398|Vega:OTTMUSG00000008798 +107997 Rtp MGI:MGI:98203 +107999 Gtpbp6 MGI:MGI:1306825|Ensembl:ENSMUSG00000033434|Vega:OTTMUSG00000026198 +108000 Cenpf MGI:MGI:1313302|Ensembl:ENSMUSG00000026605|Vega:OTTMUSG00000035168 +108001 H2-T5l2 MGI:MGI:1097694 +108004 Igkv3-1 MGI:MGI:1330851|IMGT/GENE-DB:IGKV3-1 +108005 Igkv3-7 MGI:MGI:1330852|IMGT/GENE-DB:IGKV3-7 +108010 Igkv3-8 MGI:MGI:1330857|IMGT/GENE-DB:IGKV3-8 +108011 Ap4e1 MGI:MGI:1336993|Ensembl:ENSMUSG00000001998|Vega:OTTMUSG00000016016 +108012 Ap1s2 MGI:MGI:1889383|Ensembl:ENSMUSG00000031367|Vega:OTTMUSG00000019515 +108013 Celf4 MGI:MGI:1932407|Ensembl:ENSMUSG00000024268 +108014 Srsf9 MGI:MGI:104896|Ensembl:ENSMUSG00000029538|Vega:OTTMUSG00000014654 +108015 Chrnb4 MGI:MGI:87892|Ensembl:ENSMUSG00000035200|Vega:OTTMUSG00000063102 +108017 Fxyd4 MGI:MGI:1889005|Ensembl:ENSMUSG00000004988|Vega:OTTMUSG00000056757 +108022 Igkv6-15 MGI:MGI:1330831|IMGT/GENE-DB:IGKV6-15 +108024 Igkv6-20 MGI:MGI:1330836|IMGT/GENE-DB:IGKV6-20 +108030 Lin7a MGI:MGI:2135609|Ensembl:ENSMUSG00000019906 +108031 Cor MGI:MGI:88471 +108032 Fhe MGI:MGI:95532 +108033 Usf1-rs1 MGI:MGI:99664 +108035 Ahcy-rs2 MGI:MGI:87970 +108036 Cfhe MGI:MGI:88386 +108037 Shmt2 MGI:MGI:1277989|Ensembl:ENSMUSG00000025403 +108043 Chrnb3 MGI:MGI:106212|Ensembl:ENSMUSG00000031492|Vega:OTTMUSG00000061035 +108045 Clns1a-rs2 MGI:MGI:109631 +108046 Cdc42l2 MGI:MGI:1096872 +108052 Slc14a1 MGI:MGI:1351654|Ensembl:ENSMUSG00000059336|Vega:OTTMUSG00000034695 +108058 Camk2d MGI:MGI:1341265|Ensembl:ENSMUSG00000053819|Vega:OTTMUSG00000023550 +108060 Nkx2-7 - +108062 Cstf2 MGI:MGI:1343054|Ensembl:ENSMUSG00000031256|Vega:OTTMUSG00000019011 +108067 Eif2b3 MGI:MGI:1313286|Ensembl:ENSMUSG00000028683|Vega:OTTMUSG00000009780 +108068 Grm2 MGI:MGI:1351339|Ensembl:ENSMUSG00000023192|Vega:OTTMUSG00000049456 +108069 Grm3 MGI:MGI:1351340|Ensembl:ENSMUSG00000003974|Vega:OTTMUSG00000054376 +108071 Grm5 MGI:MGI:1351342|Ensembl:ENSMUSG00000049583|Vega:OTTMUSG00000016489 +108072 Grm6 MGI:MGI:1351343|Ensembl:ENSMUSG00000000617|Vega:OTTMUSG00000007883 +108073 Grm7 MGI:MGI:1351344|Ensembl:ENSMUSG00000056755|Vega:OTTMUSG00000037574 +108075 Ltbp4 MGI:MGI:1321395|Ensembl:ENSMUSG00000040488|Vega:OTTMUSG00000031915 +108076 Ltrm5 MGI:MGI:96846 +108077 Skiv2l MGI:MGI:1099835|Ensembl:ENSMUSG00000040356|Vega:OTTMUSG00000037261 +108078 Olr1 MGI:MGI:1261434|Ensembl:ENSMUSG00000030162|Vega:OTTMUSG00000034583 +108079 Prkaa2 MGI:MGI:1336173|Ensembl:ENSMUSG00000028518|Vega:OTTMUSG00000008125 +108083 Pip4k2b MGI:MGI:1934234|Ensembl:ENSMUSG00000018547|Vega:OTTMUSG00000002742 +108084 Pphc2 MGI:MGI:104573 +108085 Itpkb-rs1 MGI:MGI:109209 +108086 Rnf216 MGI:MGI:1344349|Ensembl:ENSMUSG00000045078|Vega:OTTMUSG00000054887 +108089 Rnf144a MGI:MGI:1344401|Ensembl:ENSMUSG00000020642 +108092 Tcra-V13.2 MGI:MGI:1196230 +108093 Tcra-V13.5 MGI:MGI:1201410 +108094 Tcra-V13.4 MGI:MGI:1201411 +108095 Tcra-V13.3 MGI:MGI:1201413 +108096 Slco1a5 MGI:MGI:1351865|Ensembl:ENSMUSG00000063975|Vega:OTTMUSG00000024218 +108097 Prkab2 MGI:MGI:1336185|Ensembl:ENSMUSG00000038205|Vega:OTTMUSG00000029934 +108098 Med21 MGI:MGI:1347064|Ensembl:ENSMUSG00000030291|Vega:OTTMUSG00000025704 +108099 Prkag2 MGI:MGI:1336153|Ensembl:ENSMUSG00000028944|Vega:OTTMUSG00000023541 +108100 Baiap2 MGI:MGI:2137336|Ensembl:ENSMUSG00000025372|Vega:OTTMUSG00000004049 +108101 Fermt3 MGI:MGI:2147790|Ensembl:ENSMUSG00000024965 +108103 Supt5-rs1 MGI:MGI:1202399 +108105 B3gnt5 MGI:MGI:2137302|Ensembl:ENSMUSG00000022686|Vega:OTTMUSG00000026282 +108109 Fv5 MGI:MGI:95599 +108112 Eif4ebp3 MGI:MGI:1270847|Ensembl:ENSMUSG00000090264|Vega:OTTMUSG00000033201 +108114 Slc22a7 MGI:MGI:1859559|Ensembl:ENSMUSG00000067144 +108115 Slco4a1 MGI:MGI:1351866|Ensembl:ENSMUSG00000038963|Vega:OTTMUSG00000016331 +108116 Slco3a1 MGI:MGI:1351867|Ensembl:ENSMUSG00000025790|Vega:OTTMUSG00000024304 +108121 U2af1 MGI:MGI:98884|Ensembl:ENSMUSG00000061613 +108122 Fabp3-rs2 MGI:MGI:101930 +108123 Napg MGI:MGI:104561|Ensembl:ENSMUSG00000024581|Vega:OTTMUSG00000028127 +108124 Napa MGI:MGI:104563|Ensembl:ENSMUSG00000006024|Vega:OTTMUSG00000023922 +108127 Cdc34-rs1 MGI:MGI:1858426 +108129 Hmgcs1-rs1 MGI:MGI:109237 +108133 Rps6ka2a MGI:MGI:1354374 +108134 Rps6ka2c MGI:MGI:1354377 +108135 Rps6ka2b MGI:MGI:1354378 +108138 Xrcc4 MGI:MGI:1333799|Ensembl:ENSMUSG00000021615|Vega:OTTMUSG00000035049 +108143 Taf9 MGI:MGI:1888697|Ensembl:ENSMUSG00000052293|Ensembl:ENSMUSG00000078941|Vega:OTTMUSG00000049400 +108144 Tceb2l MGI:MGI:1860403 +108147 Atic MGI:MGI:1351352|Ensembl:ENSMUSG00000026192|Vega:OTTMUSG00000033605 +108148 Galnt2 MGI:MGI:894694|Ensembl:ENSMUSG00000089704|Ensembl:ENSMUSG00000092329|Vega:OTTMUSG00000026145|Vega:OTTMUSG00000037046 +108150 Galnt7 MGI:MGI:1349449|Ensembl:ENSMUSG00000031608|Vega:OTTMUSG00000031562 +108151 Sema3d MGI:MGI:1860118|Ensembl:ENSMUSG00000040254|Vega:OTTMUSG00000054617 +108153 Adamts7 MGI:MGI:1347346|Ensembl:ENSMUSG00000032363|Vega:OTTMUSG00000025854 +108154 Adamts6 MGI:MGI:1347348|Ensembl:ENSMUSG00000046169 +108155 Ogt MGI:MGI:1339639|Ensembl:ENSMUSG00000034160|Vega:OTTMUSG00000017263 +108156 Mthfd1 MGI:MGI:1342005|Ensembl:ENSMUSG00000021048 +108159 Ubxn8 MGI:MGI:1337129|Ensembl:ENSMUSG00000052906|Vega:OTTMUSG00000060961 +108160 Fam50a MGI:MGI:1351626|Ensembl:ENSMUSG00000001962|Vega:OTTMUSG00000017658 +108161 Fam50b MGI:MGI:1351640|Ensembl:ENSMUSG00000038246 +108163 Sdc-ps2 MGI:MGI:1349160 +108164 Klk1b23-ps MGI:MGI:891984 +108165 Klk1b28-ps MGI:MGI:891986 +108166 Sdc-rs3 MGI:MGI:1349161 +108167 Actg-ps2 MGI:MGI:87908 +108171 As2-ps1 MGI:MGI:99854 +108172 Ubl1-ps2 MGI:MGI:1197005 +108173 Ubl1-ps1 MGI:MGI:1197024 +108174 Tk-ps1 MGI:MGI:98761 +108175 Tk-ps2 MGI:MGI:98762 +108176 Npm3-ps1 MGI:MGI:894683 +108177 G6pt-ps MGI:MGI:1202716 +108178 Rnu3b-ps4 MGI:MGI:97982 +108179 Rnu3b-ps5 MGI:MGI:97983 +108180 Rnu3b-ps6 MGI:MGI:97984 +108181 Rps16-ps1 MGI:MGI:98119 +108182 Glns-ps2 MGI:MGI:95741 +108183 Rpl7-ps1 MGI:MGI:98074 +108184 Rnu6-ps3 MGI:MGI:99553 +108185 Rpl7-ps6 MGI:MGI:102532 +108186 Rpl7-ps5 MGI:MGI:102533 +108187 Rpl7-ps4 MGI:MGI:102534 +108188 Rpl7-ps3 MGI:MGI:102535 +108189 Rpl7-ps2 MGI:MGI:102536 +108190 Rps24-ps1 MGI:MGI:102575 +108191 Rpl35a-ps1 MGI:MGI:1351616 +108192 Krt1-ps MGI:MGI:99455 +108193 Cenpc-ps1 MGI:MGI:99699 +108194 Rpl30-ps4 MGI:MGI:1321397 +108195 Rpl37a-ps1 MGI:MGI:2135975 +108196 Pgk1-ps2 MGI:MGI:97557 +108197 Rap1a-ps1 MGI:MGI:97853 +108198 Krt31-ps MGI:MGI:99893 +108199 Cyp2b20-ps1 MGI:MGI:1349395 +108200 Hmgb3-ps1 MGI:MGI:1889343 +108201 Ass-ps1 MGI:MGI:88088 +108202 Nras-ps1 MGI:MGI:97377 +108203 Ppi-ps5 MGI:MGI:101879 +108204 Ppi-ps4 MGI:MGI:101880 +108205 Ppi-ps3 MGI:MGI:101881 +108206 Ppi-ps2 MGI:MGI:101882 +108207 Ppi-ps1 MGI:MGI:101883 +108211 Pim2-ps1 MGI:MGI:1345656 +108212 Rbm6-ps1 MGI:MGI:1889580 +108213 Rbm6-ps2 MGI:MGI:1889581 +108215 Hspa-ps MGI:MGI:105111 +108216 Zfy2-ps1 MGI:MGI:101933 +108217 Rps19X-ps1 MGI:MGI:107705 +108218 Cox6a-ps MGI:MGI:1333113 +108219 Odc-rs11 MGI:MGI:97405 +108220 Ifi56-ps1 MGI:MGI:99451 +108221 Ifi56-ps2 MGI:MGI:99452 +108222 Tcrg-V1ps1 MGI:MGI:104911 +108223 Clns1a-ps1 MGI:MGI:109614 +108224 Vbp1-ps1 MGI:MGI:1346083 +108225 Tyro3-rs1 MGI:MGI:104310 +108226 Hmgb1-rs23 MGI:MGI:104758 +108227 Hmgb1-rs22 MGI:MGI:104759 +108228 Hmgb1-rs21 MGI:MGI:104760 +108229 Hmgb1-rs20 MGI:MGI:104761 +108230 Hmgb1-rs19 MGI:MGI:104762 +108231 Ube2i-ps2 MGI:MGI:1333823 +108232 Ube2i-ps1 MGI:MGI:1333841 +108233 Ube2i-ps3 MGI:MGI:1333888 +108234 Snrpe-ps2 MGI:MGI:101935 +108235 Snrpe-ps1 MGI:MGI:101936 +108236 Krt6-ps1 MGI:MGI:1333779 +108237 Krt6-ps2 MGI:MGI:1333848 +108238 Grb2-ps1 MGI:MGI:99843 +108239 Dppa5-ps7 MGI:MGI:101793 +108240 Dppa5-ps6 MGI:MGI:101794 +108241 Dppa5-ps5 MGI:MGI:101795 +108242 Dppa5-ps4 MGI:MGI:101796 +108243 Dppa5-ps3 MGI:MGI:101797 +108244 Dppa5-ps2 MGI:MGI:101798 +108245 Dppa5-ps1 MGI:MGI:101799 +108246 Acta1-rs1 MGI:MGI:87903 +108247 Rny1-ps MGI:MGI:106905 +108248 Gapdh-ps13 MGI:MGI:104619 +108249 Gapdh-ps1 MGI:MGI:95641 +108250 Gapdh-ps2 MGI:MGI:95645 +108251 Gapdh-ps3 MGI:MGI:95646 +108252 Gapdh-ps4 MGI:MGI:95647 +108253 Gapdh-ps5 MGI:MGI:95648 +108254 Gapdh-ps6 MGI:MGI:95649 +108255 Gapdh-ps7 MGI:MGI:95650 +108256 Gapdh-ps8 MGI:MGI:95651 +108257 Gapdh-ps9 MGI:MGI:95652 +108258 Hnrpx-ps MGI:MGI:108428 +108259 Eif4e-ps MGI:MGI:1890160 +108260 Gapdh-ps10 MGI:MGI:95642 +108261 Gapdh-ps11 MGI:MGI:95643 +108262 Gapdh-ps12 MGI:MGI:95644 +108263 Eef2-ps1 MGI:MGI:95289 +108264 Uba1y-rs4 MGI:MGI:105389 +108265 Uba1y-rs3 MGI:MGI:105390 +108266 Uba1y-rs2 MGI:MGI:105391 +108267 Uba1y-rs1 MGI:MGI:105392 +108268 Eif4a-ps1 MGI:MGI:1195989 +108269 Ss18-ps1 MGI:MGI:2137744 +108270 Eif4a-ps9 MGI:MGI:1195957 +108271 Eif4a-ps8 MGI:MGI:1195961 +108272 Eif4a-ps3 MGI:MGI:1195964 +108273 Eif4a-ps7 MGI:MGI:1195965 +108274 Eif4a-ps6 MGI:MGI:1195978 +108275 Eif4a-ps5 MGI:MGI:1195981 +108276 Eif4a-ps2 MGI:MGI:1195982 +108277 Igk-V8-22ps MGI:MGI:1330834 +108278 Eif4a-ps10 MGI:MGI:1195979 +108279 Csf1r-rs MGI:MGI:1339757 +108280 Psme1-ps1 MGI:MGI:1341089 +108281 Lyn-ps1 MGI:MGI:104858 +108282 Psme2-ps2 MGI:MGI:1341243 +108283 Psme2-ps1 MGI:MGI:1341245 +108284 Ppp1cc-ps1 MGI:MGI:1316723 +108285 Psmc1-rs1 MGI:MGI:106047 +108286 Psma3-rs2 MGI:MGI:104881 +108287 Psma3-rs1 MGI:MGI:104882 +108289 Smt3h2-ps3 MGI:MGI:1926285 +108290 Eif4ebp1-ps2 MGI:MGI:109170 +108291 Eif4ebp1-ps1 MGI:MGI:109171 +108292 Atp5k-ps4 MGI:MGI:107702 +108293 Nzv1 MGI:MGI:97391 +108294 Nzv2 MGI:MGI:97392 +108295 Fgv2 MGI:MGI:95528 +108296 Ms6X MGI:MGI:97164 +108297 Ptv1 MGI:MGI:97818 +108298 Mmv1 MGI:MGI:97012 +108299 Mmv2 MGI:MGI:97023 +108300 Mmv3 MGI:MGI:97030 +108301 Mmv4 MGI:MGI:97031 +108302 Mmv5 MGI:MGI:97032 +108303 Mmv9 MGI:MGI:97036 +108304 Mmv6 MGI:MGI:97033 +108305 Mmv7 MGI:MGI:97034 +108306 Mmv8 MGI:MGI:97035 +108308 Mmv10 MGI:MGI:97013 +108309 Mmv12 MGI:MGI:97015 +108311 Mmv11 MGI:MGI:97014 +108312 Mmv13 MGI:MGI:97016 +108314 Tsp1 MGI:MGI:106195 +108317 Mlv1 MGI:MGI:97000 +108320 Mmv21 MGI:MGI:97025 +108321 Hrs1 MGI:MGI:96227 +108328 Mtv4 MGI:MGI:97208 +108332 Pad6 MGI:MGI:1201405 +108333 Emv36 MGI:MGI:95352 +108334 Emv51 MGI:MGI:95369 +108338 Mtv21 MGI:MGI:97189 +108339 Mtv28 MGI:MGI:97195 +108340 Mtv31 MGI:MGI:97199 +108341 Mtv42 MGI:MGI:97211 +108342 Mtv50 MGI:MGI:97220 +108343 Emv49 MGI:MGI:95366 +108344 Mtv45 MGI:MGI:97214 +108345 Bdv1 MGI:MGI:88146 +108346 Emv4 MGI:MGI:95356 +108347 Emv5 MGI:MGI:95367 +108348 Emv6 MGI:MGI:95378 +108349 Emv7 MGI:MGI:95382 +108350 Emv8 MGI:MGI:95383 +108351 Emv9 MGI:MGI:95384 +108352 Mtv5 MGI:MGI:97219 +108353 Iap2 MGI:MGI:107819 +108354 Iap1 MGI:MGI:107820 +108355 Grr MGI:MGI:894612 +108356 Akev1 MGI:MGI:104907 +108357 Olfr37 MGI:MGI:1196258 +108358 Emv10 MGI:MGI:95326 +108359 Emv40 MGI:MGI:95357 +108360 Emv61 MGI:MGI:95380 +108361 Mtv24 MGI:MGI:97191 +108362 Mtv25 MGI:MGI:97192 +108363 Mtv26 MGI:MGI:97193 +108364 Mtv46 MGI:MGI:97215 +108365 Mtv47 MGI:MGI:97216 +108366 Mtv48 MGI:MGI:97217 +108367 Mtv49 MGI:MGI:97218 +108368 Mtv51 MGI:MGI:97221 +108369 XmmvY MGI:MGI:99054 +108370 Etnmg1 MGI:MGI:109376 +108371 C58v3 MGI:MGI:88231 +108372 Loh3 MGI:MGI:1099793 +108373 Xmmv62 MGI:MGI:99035 +108374 Xmmv39 MGI:MGI:99014 +108375 Xmv1 MGI:MGI:99055 +108376 Xmv2 MGI:MGI:99066 +108377 Xmv7 MGI:MGI:99120 +108378 Srev1 MGI:MGI:98401 +108379 Srev2 MGI:MGI:98411 +108380 Srev3 MGI:MGI:98412 +108381 Srev4 MGI:MGI:98413 +108382 Srev6 MGI:MGI:98415 +108383 Srev7 MGI:MGI:98416 +108384 Srev8 MGI:MGI:98417 +108385 Srev9 MGI:MGI:98418 +108386 Xmmv1 MGI:MGI:98985 +108387 Xmmv4 MGI:MGI:99015 +108388 Xmv3 MGI:MGI:99077 +108389 Xmv4 MGI:MGI:99088 +108390 Xmv5 MGI:MGI:99098 +108391 C58v2 MGI:MGI:88230 +108392 Pmv34 MGI:MGI:97659 +108393 Pmv63 MGI:MGI:97691 +108394 Xmv11 MGI:MGI:99057 +108395 Xmv40 MGI:MGI:99089 +108396 Pmv82 MGI:MGI:107950 +108397 Srev10 MGI:MGI:98402 +108398 Srev11 MGI:MGI:98403 +108399 Srev12 MGI:MGI:98404 +108400 Srev13 MGI:MGI:98405 +108401 Srev14 MGI:MGI:98406 +108402 Srev15 MGI:MGI:98407 +108403 Srev16 MGI:MGI:98408 +108404 Srev17 MGI:MGI:98409 +108405 Srev18 MGI:MGI:98410 +108406 Xmmv10 MGI:MGI:98986 +108407 Xmmv11 MGI:MGI:98987 +108408 Xmmv12 MGI:MGI:98988 +108409 Xmmv13 MGI:MGI:98989 +108410 Xmmv14 MGI:MGI:98990 +108411 Xmmv15 MGI:MGI:98991 +108412 Xmmv16 MGI:MGI:98992 +108413 Xmmv17 MGI:MGI:98993 +108414 Xmmv18 MGI:MGI:98994 +108415 Xmmv19 MGI:MGI:98995 +108416 Xmmv20 MGI:MGI:98997 +108417 Xmmv24 MGI:MGI:99001 +108418 Xmmv25 MGI:MGI:99002 +108419 Xmmv26 MGI:MGI:99003 +108420 Xmmv28 MGI:MGI:99005 +108421 Xmmv30 MGI:MGI:99007 +108422 Xmmv32 MGI:MGI:99009 +108423 Xmmv33 MGI:MGI:99010 +108424 Xmmv37 MGI:MGI:99012 +108425 Xmmv38 MGI:MGI:99013 +108426 Xmmv40 MGI:MGI:99016 +108427 Xmmv41 MGI:MGI:99017 +108428 Xmmv43 MGI:MGI:99019 +108429 Xmmv44 MGI:MGI:99020 +108430 Xmmv45 MGI:MGI:99021 +108431 Xmmv46 MGI:MGI:99022 +108432 Xmmv48 MGI:MGI:99024 +108433 Xmmv49 MGI:MGI:99025 +108434 Xmmv51 MGI:MGI:99027 +108435 Xmmv53 MGI:MGI:99028 +108436 Xmmv56 MGI:MGI:99030 +108437 Xmmv57 MGI:MGI:99031 +108438 Xmmv59 MGI:MGI:99033 +108439 Xmmv60 MGI:MGI:99034 +108440 Xmmv63 MGI:MGI:99036 +108441 Xmmv64 MGI:MGI:99037 +108442 Xmmv66 MGI:MGI:99039 +108443 Xmmv68 MGI:MGI:99041 +108444 Xmmv69 MGI:MGI:99042 +108445 Xmmv70 MGI:MGI:99044 +108446 Xmmv78 MGI:MGI:99051 +108447 Tcra-V20 MGI:MGI:106052 +108448 Pmv52 MGI:MGI:97679 +108449 Pmv60 MGI:MGI:97688 +108450 Pmv61 MGI:MGI:97689 +108451 Pmv64 MGI:MGI:97692 +108452 Pmv66 MGI:MGI:97694 +108453 Pmv68 MGI:MGI:97696 +108454 Pmv69 MGI:MGI:97697 +108455 Xmv56 MGI:MGI:99105 +108456 Xmv64 MGI:MGI:99114 +108457 Xmv66 MGI:MGI:99116 +108458 Ms46 MGI:MGI:1321097 +108459 Ms56 MGI:MGI:1321105 +108460 Ms53 MGI:MGI:1321108 +108461 Ms64 MGI:MGI:1321122 +108462 Ms61 MGI:MGI:1321136 +108463 Ms20 MGI:MGI:1321140 +108464 Ms34 MGI:MGI:1321147 +108465 Ms36 MGI:MGI:1321149 +108466 Ms40 MGI:MGI:1321099 +108467 Ms42 MGI:MGI:1321101 +108468 Ms62 MGI:MGI:1321116 +108469 Ms65 MGI:MGI:1321123 +108470 Ms28 MGI:MGI:1321134 +108471 Ms37 MGI:MGI:1321148 +108472 Ms4 MGI:MGI:1321086 +108473 Ms88 MGI:MGI:1321069 +108474 Ms89 MGI:MGI:1321070 +108475 Ms95 MGI:MGI:1321072 +108476 Ms82 MGI:MGI:1321073 +108477 Ms85 MGI:MGI:1321075 +108478 Ms86 MGI:MGI:1321076 +108479 Ms87 MGI:MGI:1321077 +108480 Ms93 MGI:MGI:1321078 +108481 Ms92 MGI:MGI:1321079 +108482 Ms91 MGI:MGI:1321080 +108483 Ms97 MGI:MGI:1321082 +108484 Ms59 MGI:MGI:1321102 +108485 Ms55 MGI:MGI:1321106 +108486 Ms75 MGI:MGI:1321110 +108487 Ms74 MGI:MGI:1321111 +108488 Ms77 MGI:MGI:1321112 +108489 Ms76 MGI:MGI:1321124 +108490 Ms10 MGI:MGI:1321128 +108491 Ms96 MGI:MGI:1321139 +108492 Ms94 MGI:MGI:1321144 +108493 Ms90 MGI:MGI:1321154 +108494 Emvc2 MGI:MGI:95386 +108497 Emvc1 MGI:MGI:95385 +108498 Dgcr3 MGI:MGI:1343186 +108499 Dgcr5 MGI:MGI:1343187 +108500 Mpmv10 MGI:MGI:97078 +108501 Minte MGI:MGI:96987 +108502 Mintf MGI:MGI:96988 +108503 Minth MGI:MGI:96989 +108504 Mpmv30 MGI:MGI:97100 +108505 Ms15-4 MGI:MGI:97152 +108508 Ms13-5 MGI:MGI:103102 +108509 Ms13-8 MGI:MGI:103132 +108510 Ms13-4 MGI:MGI:103119 +108511 Ms13-7 MGI:MGI:103125 +108512 Ms13-1 MGI:MGI:103130 +108513 Mpmv26 MGI:MGI:97095 +108514 Mpmv31 MGI:MGI:97101 +108515 Ms13-34 MGI:MGI:103103 +108516 Ms13-24 MGI:MGI:103104 +108517 Ms13-12 MGI:MGI:103105 +108518 Ms13-32 MGI:MGI:103112 +108519 Ms13-29 MGI:MGI:103113 +108520 Ms13-26 MGI:MGI:103114 +108521 Ms13-30 MGI:MGI:103133 +108522 Ms13-13 MGI:MGI:103134 +108523 Ms13-18 MGI:MGI:103121 +108524 Ms13-17 MGI:MGI:103122 +108525 Ms13-25 MGI:MGI:103126 +108526 Ms13-38 MGI:MGI:103127 +108527 Ms13-37 MGI:MGI:103128 +108528 Ms13-21 MGI:MGI:103129 +108529 Grcl MGI:MGI:1345677 +108531 Ms13-9 MGI:MGI:103082 +108532 Ms13-6 MGI:MGI:103083 +108533 Ms13-3 MGI:MGI:103088 +108534 Ms13-2 MGI:MGI:103093 +108535 Ms13-36 MGI:MGI:103084 +108536 Ms13-35 MGI:MGI:103085 +108537 Ms13-33 MGI:MGI:103086 +108538 Ms13-31 MGI:MGI:103087 +108539 Ms13-28 MGI:MGI:103089 +108540 Ms13-27 MGI:MGI:103090 +108541 Ms13-23 MGI:MGI:103091 +108542 Ms13-22 MGI:MGI:103092 +108543 Ms13-16 MGI:MGI:103094 +108544 Ms13-14 MGI:MGI:103095 +108545 Ms13-11 MGI:MGI:103096 +108546 Ms13-20 MGI:MGI:103131 +108547 Iapls1-28 MGI:MGI:96323 +108548 Iapls3-39 MGI:MGI:99799 +108549 Iapls3-34 MGI:MGI:99802 +108550 Iapls2-26 MGI:MGI:102852 +108551 Iapls2-37 MGI:MGI:102893 +108552 Iapls2-35 MGI:MGI:102894 +108553 Iapls1-26 MGI:MGI:96321 +108554 Iapls1-27 MGI:MGI:96322 +108555 Iapls3-27 MGI:MGI:96371 +108556 Tkns1 MGI:MGI:99428 +108557 Iapls3-25 MGI:MGI:99807 +108558 Iapls1-69 MGI:MGI:102942 +108559 Iapls2-20 MGI:MGI:102945 +108560 Iapls2-17 MGI:MGI:102946 +108561 Iapls1-74 MGI:MGI:102947 +108562 Iapls1-35 MGI:MGI:102948 +108563 Iapls1-37 MGI:MGI:1270846 +108564 Iapls2-8 MGI:MGI:96352 +108565 Iapls1-53 MGI:MGI:96329 +108566 Iapls1-54 MGI:MGI:96330 +108567 Iapls1-57 MGI:MGI:96331 +108568 Iapls2-29 MGI:MGI:96344 +108569 Iapls2-31 MGI:MGI:96346 +108570 Iap5rc1 MGI:MGI:99376 +108571 Iap3ra18 MGI:MGI:99282 +108572 Iap3rc20 MGI:MGI:99323 +108573 Iap5rc20 MGI:MGI:99388 +108574 Iapls3-68 MGI:MGI:102929 +108575 Iap5rc17 MGI:MGI:99384 +108576 Iap3ra2 MGI:MGI:99283 +108577 Iap3ra4 MGI:MGI:99285 +108578 Iap3ra6 MGI:MGI:99287 +108579 Iap3ra7 MGI:MGI:99288 +108580 Iap3rb2 MGI:MGI:99303 +108581 Iap3rb4 MGI:MGI:99305 +108582 Iap3rb7 MGI:MGI:99308 +108583 Iap3rc3 MGI:MGI:99332 +108584 Iap3rc5 MGI:MGI:99334 +108585 Iap3rc7 MGI:MGI:99336 +108586 Iap5ra3 MGI:MGI:99345 +108587 Iap5ra6 MGI:MGI:99348 +108588 Iap5ra8 MGI:MGI:99350 +108589 Iap5ra9 MGI:MGI:99351 +108590 Iap5rb9 MGI:MGI:99375 +108591 Iap5rc7 MGI:MGI:99395 +108592 Iap5rc8 MGI:MGI:99396 +108593 Iap5rc9 MGI:MGI:99397 +108594 Iapls3-51 MGI:MGI:102856 +108595 Iapls3-46 MGI:MGI:102857 +108598 Iap3ra11 MGI:MGI:99275 +108599 Iap3ra12 MGI:MGI:99276 +108600 Iap3ra13 MGI:MGI:99277 +108601 Iap3ra15 MGI:MGI:99279 +108602 Iap3ra16 MGI:MGI:99280 +108603 Iap3rb15 MGI:MGI:99297 +108604 Iap3rb16 MGI:MGI:99298 +108605 Iap3rc12 MGI:MGI:99314 +108606 Iap3rc14 MGI:MGI:99316 +108607 Iap3rc16 MGI:MGI:99318 +108608 Iap3rc19 MGI:MGI:99321 +108609 Iap3rc21 MGI:MGI:99324 +108610 Iap3rc22 MGI:MGI:99325 +108611 Iap3rc23 MGI:MGI:99326 +108612 Iap3rc25 MGI:MGI:99328 +108613 Iap3rc26 MGI:MGI:99329 +108614 Iap3rc28 MGI:MGI:99331 +108615 Iap5ra12 MGI:MGI:99342 +108616 Iap5ra13 MGI:MGI:99343 +108617 Iap5rb15 MGI:MGI:99358 +108618 Iap5rb16 MGI:MGI:99359 +108619 Iap5rb17 MGI:MGI:99360 +108620 Iap5rb18 MGI:MGI:99361 +108621 Iap5rb19 MGI:MGI:99362 +108622 Iap5rb20 MGI:MGI:99364 +108623 Iap5rb21 MGI:MGI:99365 +108624 Iap5rb22 MGI:MGI:99366 +108625 Iap5rb23 MGI:MGI:99367 +108626 Iap5rc13 MGI:MGI:99380 +108627 Iap5rc14 MGI:MGI:99381 +108628 Iap5rc15 MGI:MGI:99382 +108629 Iap5rc18 MGI:MGI:99385 +108630 Iap5rc19 MGI:MGI:99386 +108631 Iap5rc22 MGI:MGI:99390 +108632 Pltr16 MGI:MGI:99618 +108633 Edv3 MGI:MGI:107694 +108634 Edv2 MGI:MGI:107695 +108635 Igk-Vt MGI:MGI:1333116 +108636 Mltr5 MGI:MGI:99628 +108637 Snord14c MGI:MGI:97971|Ensembl:ENSMUSG00000096263 +108638 Snord21 MGI:MGI:102855 +108639 BY367451 MGI:MGI:1891412 +108640 Copg2os1 MGI:MGI:1858742 +108645 Mat2b MGI:MGI:1913667|Ensembl:ENSMUSG00000042032|Vega:OTTMUSG00000005433 +108652 Slc35b3 MGI:MGI:1913978|Ensembl:ENSMUSG00000021432 +108653 Rimklb MGI:MGI:1918325|Ensembl:ENSMUSG00000040649|Vega:OTTMUSG00000022378 +108654 Fam210a MGI:MGI:1914000|Ensembl:ENSMUSG00000038121|Vega:OTTMUSG00000023928 +108655 Foxp1 MGI:MGI:1914004|Ensembl:ENSMUSG00000030067|Vega:OTTMUSG00000022717 +108657 Rnpepl1 MGI:MGI:1914170|Ensembl:ENSMUSG00000026269|Vega:OTTMUSG00000042343 +108660 Rnf187 MGI:MGI:1914224|Ensembl:ENSMUSG00000020496|Vega:OTTMUSG00000005779 +108664 Atp6v1h MGI:MGI:1914864|Ensembl:ENSMUSG00000033793|Vega:OTTMUSG00000050145 +108670 Epsti1 MGI:MGI:1915168|Ensembl:ENSMUSG00000022014 +108671 Dnajc9 MGI:MGI:1915326|Ensembl:ENSMUSG00000021811 +108672 Zdhhc15 MGI:MGI:1915336|Ensembl:ENSMUSG00000033906|Vega:OTTMUSG00000018109 +108673 Ccdc86 MGI:MGI:1277220|Ensembl:ENSMUSG00000024732|Vega:OTTMUSG00000033058 +108679 Cops8 MGI:MGI:1915363|Ensembl:ENSMUSG00000034432|Vega:OTTMUSG00000048401 +108682 Gpt2 MGI:MGI:1915391|Ensembl:ENSMUSG00000031700|Vega:OTTMUSG00000023224 +108686 Ccdc88a MGI:MGI:1925177|Ensembl:ENSMUSG00000032740|Vega:OTTMUSG00000005327 +108687 Edem2 MGI:MGI:1915540|Ensembl:ENSMUSG00000038312|Vega:OTTMUSG00000016134 +108689 Stn1 MGI:MGI:1915581|Ensembl:ENSMUSG00000042694|Vega:OTTMUSG00000043314 +108699 Chn1 MGI:MGI:1915674|Ensembl:ENSMUSG00000056486|Vega:OTTMUSG00000013428 +108701 1110037P09Rik MGI:MGI:1916001 +108705 Pttg1ip MGI:MGI:2652132|Ensembl:ENSMUSG00000009291|Vega:OTTMUSG00000035073 +108707 Fam207a MGI:MGI:1916334|Ensembl:ENSMUSG00000032977 +108713 2610028H08Rik MGI:MGI:1916485 +108723 Card11 MGI:MGI:1916978|Ensembl:ENSMUSG00000036526|Vega:OTTMUSG00000054841 +108735 Sft2d2 MGI:MGI:1917362|Ensembl:ENSMUSG00000040848|Vega:OTTMUSG00000049874 +108737 Oxsr1 MGI:MGI:1917378|Ensembl:ENSMUSG00000036737|Vega:OTTMUSG00000030092 +108743 2210408K08Rik MGI:MGI:1917430 +108751 2700088P18Rik MGI:MGI:1917492 +108755 Lyrm2 MGI:MGI:1917573|Ensembl:ENSMUSG00000045854|Vega:OTTMUSG00000004974 +108760 Galnt16 MGI:MGI:1917754|Ensembl:ENSMUSG00000021130 +108767 Pnrc1 MGI:MGI:1917838|Ensembl:ENSMUSG00000040128|Vega:OTTMUSG00000004941 +108769 5730563F14Rik MGI:MGI:1917893 +108797 Mex3b MGI:MGI:1918252|Ensembl:ENSMUSG00000057706|Vega:OTTMUSG00000059230 +108800 Ston2 MGI:MGI:1918272|Ensembl:ENSMUSG00000020961|Vega:OTTMUSG00000035527 +108802 Calr4 MGI:MGI:2140435|Ensembl:ENSMUSG00000028558|Vega:OTTMUSG00000008291 +108803 4933402P03Rik MGI:MGI:1918293|Ensembl:ENSMUSG00000044084|Vega:OTTMUSG00000005996 +108807 4933415E08Rik MGI:MGI:1918329 +108809 4933407E24Rik MGI:MGI:1918352 +108811 Ccdc122 MGI:MGI:1918358|Ensembl:ENSMUSG00000034795|Vega:OTTMUSG00000027799 +108812 Als2cr12 MGI:MGI:1918359|Ensembl:ENSMUSG00000047528|Vega:OTTMUSG00000047212 +108816 4933409K07Rik MGI:MGI:1918429 +108829 Jmjd1c MGI:MGI:1918614|Ensembl:ENSMUSG00000037876|Vega:OTTMUSG00000037955 +108830 5530401I05Rik MGI:MGI:1918626 +108832 Tmem74b MGI:MGI:1918629|Ensembl:ENSMUSG00000044364|Vega:OTTMUSG00000015841 +108837 Ibtk MGI:MGI:1918677|Ensembl:ENSMUSG00000035941|Vega:OTTMUSG00000045033 +108841 Rdh13 MGI:MGI:1918732|Ensembl:ENSMUSG00000008435|Vega:OTTMUSG00000022761 +108853 Mtrf1l MGI:MGI:1918830|Ensembl:ENSMUSG00000019774|Vega:OTTMUSG00000022750 +108857 Ankhd1 MGI:MGI:1921733|Ensembl:ENSMUSG00000024483|Vega:OTTMUSG00000034846 +108858 9130020K20Rik MGI:MGI:1918848 +108870 4930447K04Rik MGI:MGI:1918901 +108871 4930447M23Rik MGI:MGI:1918902 +108876 2610017A05Rik MGI:MGI:1919056 +108888 Atad3a MGI:MGI:1919214|Ensembl:ENSMUSG00000029036|Vega:OTTMUSG00000010851 +108897 Aif1l MGI:MGI:1919598|Ensembl:ENSMUSG00000001864|Vega:OTTMUSG00000012243 +108899 2700081O15Rik MGI:MGI:1919667|Ensembl:ENSMUSG00000053080|Vega:OTTMUSG00000034222 +108900 Fam72a MGI:MGI:1919669|Ensembl:ENSMUSG00000055184|Vega:OTTMUSG00000021788 +108902 B4gat1 MGI:MGI:1919680|Ensembl:ENSMUSG00000047379 +108903 Tbcd MGI:MGI:1919686|Ensembl:ENSMUSG00000039230|Vega:OTTMUSG00000004679 +108907 Nusap1 MGI:MGI:2675669|Ensembl:ENSMUSG00000027306|Vega:OTTMUSG00000015954 +108909 Aida MGI:MGI:1919737|Ensembl:ENSMUSG00000042901|Vega:OTTMUSG00000050559 +108911 Rcc2 MGI:MGI:1919784|Ensembl:ENSMUSG00000040945|Vega:OTTMUSG00000010024 +108912 Cdca2 MGI:MGI:1919787|Ensembl:ENSMUSG00000048922|Vega:OTTMUSG00000033334 +108927 Lhfp MGI:MGI:1920048|Ensembl:ENSMUSG00000048332|Vega:OTTMUSG00000032739 +108934 Smim13 MGI:MGI:2652854|Ensembl:ENSMUSG00000091264|Vega:OTTMUSG00000037599 +108937 Rnf169 MGI:MGI:1920257|Ensembl:ENSMUSG00000058761|Vega:OTTMUSG00000035320 +108943 Trmt10a MGI:MGI:1920421|Ensembl:ENSMUSG00000004127|Vega:OTTMUSG00000027229 +108946 Zzz3 MGI:MGI:1920453|Ensembl:ENSMUSG00000039068|Vega:OTTMUSG00000017427 +108950 1700049L16Rik MGI:MGI:1920633 +108954 Ppp1r15b MGI:MGI:2444211|Ensembl:ENSMUSG00000046062|Vega:OTTMUSG00000022095 +108956 Apol7c MGI:MGI:1920912|Ensembl:ENSMUSG00000044309 +108958 Miga2 MGI:MGI:1922035|Ensembl:ENSMUSG00000026858|Vega:OTTMUSG00000016796 +108960 Irak2 MGI:MGI:2429603|Ensembl:ENSMUSG00000060477|Vega:OTTMUSG00000023746 +108961 E2f8 MGI:MGI:1922038|Ensembl:ENSMUSG00000046179|Vega:OTTMUSG00000029718 +108962 4833441D16Rik MGI:MGI:1922039 +108970 4930519F24Rik MGI:MGI:1922047|Ensembl:ENSMUSG00000101584 +108971 4930544C05Rik MGI:MGI:1922048 +108976 4930551A22Rik MGI:MGI:1922053 +108978 4930555G01Rik MGI:MGI:1922055|Ensembl:ENSMUSG00000096197|Vega:OTTMUSG00000036249 +108985 2610021C13Rik MGI:MGI:1922062 +108989 Tpr MGI:MGI:1922066|Ensembl:ENSMUSG00000006005|Vega:OTTMUSG00000029496 +108995 Tbc1d10c MGI:MGI:1922072|Ensembl:ENSMUSG00000040247 +109006 Ciapin1 MGI:MGI:1922083|Ensembl:ENSMUSG00000031781|Vega:OTTMUSG00000027367 +109010 2010010I01Rik MGI:MGI:1922087 +109011 1700020M10Rik MGI:MGI:1922812 +109019 Nabp1 MGI:MGI:1923258|Ensembl:ENSMUSG00000026107|Vega:OTTMUSG00000046715 +109032 Sp110 MGI:MGI:1923364|Ensembl:ENSMUSG00000070034|Vega:OTTMUSG00000024589 +109036 6230415J03Rik MGI:MGI:1923398 +109042 Cavin3 MGI:MGI:1923422|Ensembl:ENSMUSG00000037060|Vega:OTTMUSG00000060469 +109046 6430501K19Rik MGI:MGI:1923450 +109050 Fam212b MGI:MGI:1923497|Ensembl:ENSMUSG00000048458|Vega:OTTMUSG00000022100 +109052 Krt75 MGI:MGI:1923500|Ensembl:ENSMUSG00000022986|Vega:OTTMUSG00000028197 +109054 Pfdn4 MGI:MGI:1923512|Ensembl:ENSMUSG00000052033|Vega:OTTMUSG00000016125 +109065 Dnaaf2 MGI:MGI:1923566|Ensembl:ENSMUSG00000020973|Vega:OTTMUSG00000023796 +109075 Exosc4 MGI:MGI:1923576|Ensembl:ENSMUSG00000034259|Vega:OTTMUSG00000035760 +109077 Ints5 MGI:MGI:1923578|Ensembl:ENSMUSG00000071652 +109079 Sephs1 MGI:MGI:1923580|Ensembl:ENSMUSG00000026662|Vega:OTTMUSG00000010816 +109082 Fbxw17 MGI:MGI:1923584|Ensembl:ENSMUSG00000037816|Vega:OTTMUSG00000041997 +109093 Rars2 MGI:MGI:1923596|Ensembl:ENSMUSG00000028292|Vega:OTTMUSG00000006415 +109095 Rbm15b MGI:MGI:1923598|Ensembl:ENSMUSG00000074102|Vega:OTTMUSG00000032631 +109108 Slc30a9 MGI:MGI:1923690|Ensembl:ENSMUSG00000029221|Vega:OTTMUSG00000030420 +109113 Uhrf2 MGI:MGI:1923718|Ensembl:ENSMUSG00000024817|Vega:OTTMUSG00000017310 +109115 Supt3 MGI:MGI:1923723|Ensembl:ENSMUSG00000038954|Vega:OTTMUSG00000030963 +109129 Mmadhc MGI:MGI:1923786|Ensembl:ENSMUSG00000026766|Vega:OTTMUSG00000012388 +109135 Plekha5 MGI:MGI:1923802|Ensembl:ENSMUSG00000030231|Vega:OTTMUSG00000056993 +109136 Mmaa MGI:MGI:1923805|Ensembl:ENSMUSG00000037022|Vega:OTTMUSG00000061306 +109145 Gins4 MGI:MGI:1923847|Ensembl:ENSMUSG00000031546|Vega:OTTMUSG00000060900 +109151 Chd9 MGI:MGI:1924001|Ensembl:ENSMUSG00000056608|Vega:OTTMUSG00000061365 +109154 Mlec MGI:MGI:1924015|Ensembl:ENSMUSG00000048578|Vega:OTTMUSG00000014632 +109161 Ube2q2 MGI:MGI:2388672|Ensembl:ENSMUSG00000032307|Vega:OTTMUSG00000023433 +109163 3010003L21Rik MGI:MGI:1924094 +109168 Atl3 MGI:MGI:1924270|Ensembl:ENSMUSG00000024759 +109169 Igip MGI:MGI:1924271|Ensembl:ENSMUSG00000110185|Vega:OTTMUSG00000060490 +109170 2810428M03Rik MGI:MGI:1924283 +109181 Trip11 MGI:MGI:1924393|Ensembl:ENSMUSG00000021188|Vega:OTTMUSG00000039943 +109186 6720427I07Rik MGI:MGI:1924398 +109191 9430025N12Rik MGI:MGI:1924403 +109198 6030407O03Rik MGI:MGI:1924410|Ensembl:ENSMUSG00000100301 +109200 A430102J17Rik MGI:MGI:1924412 +109201 A930017D03Rik MGI:MGI:1924413 +109202 A930024E05Rik MGI:MGI:1924414|Ensembl:ENSMUSG00000056735 +109205 Sobp MGI:MGI:1924427|Ensembl:ENSMUSG00000038248|Vega:OTTMUSG00000046585 +109206 5930412I24Rik MGI:MGI:1924428 +109208 5930420B01Rik MGI:MGI:1924430 +109212 Pimreg MGI:MGI:1924434|Ensembl:ENSMUSG00000020808|Vega:OTTMUSG00000025763 +109215 Lncbate1 MGI:MGI:1924437|Ensembl:ENSMUSG00000110613 +109218 Tmem139 MGI:MGI:1924444|Ensembl:ENSMUSG00000071506 +109222 Rarres1 MGI:MGI:1924461|Ensembl:ENSMUSG00000049404|Vega:OTTMUSG00000030597 +109225 Ms4a7 MGI:MGI:1918846|Ensembl:ENSMUSG00000024672|Vega:OTTMUSG00000028835 +109226 A930002I21Rik MGI:MGI:1924480 +109229 Fam118b MGI:MGI:1924483|Ensembl:ENSMUSG00000050471|Vega:OTTMUSG00000031571 +109232 Sccpdh MGI:MGI:1924486|Ensembl:ENSMUSG00000038936|Vega:OTTMUSG00000021897 +109237 A030007N12Rik MGI:MGI:1924511 +109241 Mbd5 MGI:MGI:2138934|Ensembl:ENSMUSG00000036792|Vega:OTTMUSG00000012482 +109242 Kif24 MGI:MGI:1918345|Ensembl:ENSMUSG00000028438|Vega:OTTMUSG00000006662 +109245 Lrrc39 MGI:MGI:1924557|Ensembl:ENSMUSG00000027961|Vega:OTTMUSG00000022732 +109246 Tspan9 MGI:MGI:1924558|Ensembl:ENSMUSG00000030352|Vega:OTTMUSG00000022481 +109253 9430041P20Rik MGI:MGI:1924595 +109254 Adtrp MGI:MGI:1924596|Ensembl:ENSMUSG00000058022|Vega:OTTMUSG00000029811 +109260 C030018P15Rik MGI:MGI:1924635 +109263 Rlf MGI:MGI:1924705|Ensembl:ENSMUSG00000049878|Vega:OTTMUSG00000008901 +109264 Me3 MGI:MGI:1916679|Ensembl:ENSMUSG00000030621|Vega:OTTMUSG00000025905 +109267 Ssc4d MGI:MGI:1924709|Ensembl:ENSMUSG00000029699|Vega:OTTMUSG00000023659 +109268 9430090L19Rik MGI:MGI:1924710 +109270 Prr5 MGI:MGI:1924714|Ensembl:ENSMUSG00000036106|Vega:OTTMUSG00000035390 +109272 Mybpc1 MGI:MGI:1336213|Ensembl:ENSMUSG00000020061|Vega:OTTMUSG00000031731 +109275 Actr5 MGI:MGI:1924748|Ensembl:ENSMUSG00000037761|Vega:OTTMUSG00000015937 +109279 9530010C24Rik MGI:MGI:1924752 +109280 Slc22a13b-ps MGI:MGI:1924762|Ensembl:ENSMUSG00000092212|Vega:OTTMUSG00000035361 +109284 R3hdm4 MGI:MGI:1924814|Ensembl:ENSMUSG00000035781 +109288 9330115C17Rik MGI:MGI:1924818 +109292 4631423B10Rik MGI:MGI:1924838 +109294 Prex2 MGI:MGI:1923385|Ensembl:ENSMUSG00000048960|Vega:OTTMUSG00000047927 +109299 Tmem250-ps MGI:MGI:1924939 +109304 B230118I11Rik MGI:MGI:1925541 +109305 Orai1 MGI:MGI:1925542|Ensembl:ENSMUSG00000049686|Vega:OTTMUSG00000026744 +109314 Prr9 MGI:MGI:1925680|Ensembl:ENSMUSG00000056270|Vega:OTTMUSG00000052636 +109319 8430422M14Rik MGI:MGI:1925753 +109323 C1qtnf7 MGI:MGI:1925911|Ensembl:ENSMUSG00000061535|Vega:OTTMUSG00000026743 +109331 Rnf20 MGI:MGI:1925927|Ensembl:ENSMUSG00000028309|Vega:OTTMUSG00000006927 +109332 Cdcp1 MGI:MGI:2442010|Ensembl:ENSMUSG00000035498|Vega:OTTMUSG00000027392 +109333 Pkn2 MGI:MGI:109211|Ensembl:ENSMUSG00000004591|Vega:OTTMUSG00000036912 +109334 B230398E01Rik MGI:MGI:1925930 +109335 9230102K24Rik MGI:MGI:1925931|Ensembl:ENSMUSG00000112398 +109339 2700018L05Rik MGI:MGI:1926019 +109342 Slc5a10 MGI:MGI:1926089|Ensembl:ENSMUSG00000042371|Vega:OTTMUSG00000005841 +109343 C330020G15Rik MGI:MGI:1926090 +109344 E130215H24Rik MGI:MGI:1926091|Ensembl:ENSMUSG00000087406 +109346 Ankrd39 MGI:MGI:1914816|Ensembl:ENSMUSG00000079610|Vega:OTTMUSG00000049837 +109349 Fam163b MGI:MGI:1926106|Ensembl:ENSMUSG00000009216|Vega:OTTMUSG00000011847 +109356 9530053P14Rik MGI:MGI:1926113 +109358 C330026H20Rik MGI:MGI:1926115 +109359 Abraxas2 MGI:MGI:1926116|Ensembl:ENSMUSG00000030965|Vega:OTTMUSG00000025665 +109360 D530018E20Rik MGI:MGI:1926117 +109361 D730005E14Rik MGI:MGI:1926118 +109364 El5 MGI:MGI:108206 +109365 El6 MGI:MGI:108225 +109367 Obq1 MGI:MGI:109204 +109368 Eye2 MGI:MGI:1336890 +109369 Obq6 MGI:MGI:1349402 +109370 Emo1 MGI:MGI:1350920 +109371 Fecq2 MGI:MGI:1329007 +109372 Bw3 MGI:MGI:104775 +109373 Bw2 MGI:MGI:104776 +109374 Bw1 MGI:MGI:104777 +109375 Dob1 MGI:MGI:99952 +109376 Lbw5 MGI:MGI:105957 +109377 Lbw4 MGI:MGI:105960 +109378 Lbw3 MGI:MGI:105961 +109379 Lbw2 MGI:MGI:105965 +109380 Lbw6 MGI:MGI:105944 +109381 Lbw1 MGI:MGI:105945 +109382 Lbw8 MGI:MGI:105952 +109383 Bwq2 MGI:MGI:1298233 +109384 Bwq3 MGI:MGI:1890413 +109385 Bwq4 MGI:MGI:1890414 +109386 Tms MGI:MGI:98776 +109387 Cbm1 MGI:MGI:1891174 +109388 Cbm2 MGI:MGI:1891175 +109389 Twq1 MGI:MGI:1277986 +109390 Cbm3 MGI:MGI:1891176 +109391 Cbm4 MGI:MGI:1891177 +109392 Cbm5 MGI:MGI:2137569 +109393 Livq3 MGI:MGI:1344420 +109394 Fob1 MGI:MGI:1353459 +109395 Fob4 MGI:MGI:1353461 +109396 Oriq4 MGI:MGI:1196344 +109397 Oriq3 MGI:MGI:1196401 +109398 Fob3 MGI:MGI:1353457 +109399 Fob2 MGI:MGI:1353458 +109400 Spm1 MGI:MGI:2137854 +109401 Pact1 MGI:MGI:1100875 +109402 Bmd2 MGI:MGI:1349433 +109403 Etohc3 MGI:MGI:1858453 +109404 Sbw2 MGI:MGI:105964 +109405 Sbw1 MGI:MGI:105970 +109406 Bmd3 MGI:MGI:1349432 +109407 Bmd4 MGI:MGI:1349437 +109408 Gusr MGI:MGI:1932465 +109409 Tbs1 MGI:MGI:1345631 +109410 Aliq2 MGI:MGI:1345619 +109411 Aliq3 MGI:MGI:1345620 +109412 Szs6 MGI:MGI:1345672 +109413 Aaiq3 MGI:MGI:1196362 +109414 Aaiq4 MGI:MGI:1196364 +109415 Imm1 MGI:MGI:105966 +109416 Bwfq1 MGI:MGI:1201373 +109417 Bwfq2 MGI:MGI:1201415 +109418 Lmr30 MGI:MGI:1346073 +109419 Mol1 MGI:MGI:1353475 +109420 Mol2 MGI:MGI:1353476 +109421 Hpi2 MGI:MGI:1890582 +109422 Mol3 MGI:MGI:1353477 +109423 Mol4 MGI:MGI:1353478 +109424 Hpi1 MGI:MGI:1890581 +109425 Bslm1 MGI:MGI:2137478 +109426 Bslm3 MGI:MGI:2137480 +109427 Skts3 MGI:MGI:104791 +109428 Daq2 MGI:MGI:1098254 +109429 Bslm2 MGI:MGI:2137479 +109430 Gvhd2 MGI:MGI:1346067 +109431 Sprol1 MGI:MGI:1343153 +109432 Wt3q3 MGI:MGI:1344429 +109433 Scc7 MGI:MGI:1347108 +109434 Scc8 MGI:MGI:1347109 +109435 Remslp5 MGI:MGI:2137676 +109436 Scc6 MGI:MGI:1347107 +109437 Etlm1 MGI:MGI:2137481 +109438 Etlm2 MGI:MGI:2137482 +109439 Etlm3 MGI:MGI:2137483 +109443 Rapop1 MGI:MGI:103275 +109445 Pbd2 MGI:MGI:1345613 +109447 Par2 MGI:MGI:1855887 +109448 Pas1b MGI:MGI:109208 +109449 Bhr5 MGI:MGI:1351272 +109450 Hpic1 MGI:MGI:2137472 +109451 Hpic2 MGI:MGI:2137474 +109452 Cia6 MGI:MGI:1345671 +109453 Hpic3 MGI:MGI:2137476 +109454 Hpic4 MGI:MGI:2137477 +109455 Cia1 MGI:MGI:1345674 +109456 Exq3 MGI:MGI:1314869 +109457 Pas9 MGI:MGI:1345292 +109458 Estq2 MGI:MGI:1346095 +109459 Estq1 MGI:MGI:1346097 +109460 Pas1c MGI:MGI:1345294 +109461 Tlsr4 MGI:MGI:1345498 +109462 Tlsr5 MGI:MGI:1345499 +109463 Pas10 MGI:MGI:1345293 +109464 Pas5b MGI:MGI:1345295 +109465 Cms1 MGI:MGI:1346025 +109466 Cms2 MGI:MGI:1346026 +109467 Pas2 MGI:MGI:97482 +109468 Itbq1 MGI:MGI:1328329 +109469 Hcs3 MGI:MGI:96058 +109470 Crhq1 MGI:MGI:1298385 +109471 Lore1 MGI:MGI:1096557 +109472 Lore7 MGI:MGI:1096563 +109473 Lore6 MGI:MGI:1096564 +109474 Pas3a MGI:MGI:1345290 +109475 Pas1a MGI:MGI:1345296 +109476 Hcbip2 MGI:MGI:1345640 +109477 Hcbip1 MGI:MGI:1345654 +109478 Mlviq2 MGI:MGI:1306808 +109479 Yaa1 MGI:MGI:1345663 +109480 Aem2 MGI:MGI:2137852 +109481 Sles4 MGI:MGI:1353456 +109482 Sles2 MGI:MGI:1353462 +109483 Sles3 MGI:MGI:1353463 +109484 Aem3 MGI:MGI:2137853 +109485 Cplaq1 MGI:MGI:1277094 +109486 Cplaq4 MGI:MGI:1277130 +109487 Cplaq3 MGI:MGI:1277142 +109488 Cplaq5 MGI:MGI:1277144 +109489 Cplaq7 MGI:MGI:1277146 +109490 Cplaq6 MGI:MGI:1277147 +109491 Sles1 MGI:MGI:1353464 +109492 Nidd1 MGI:MGI:1277966 +109493 Alcp5 MGI:MGI:1858454 +109494 Alcp7 MGI:MGI:1858456 +109495 Alcp9 MGI:MGI:1858458 +109496 Nidd3 MGI:MGI:1277970 +109497 Grdhq1 MGI:MGI:1343202 +109498 Alcp11 MGI:MGI:1858390 +109499 Alcp12 MGI:MGI:1858391 +109500 Dssc2 MGI:MGI:1345664 +109501 Dssc1 MGI:MGI:1345666 +109502 Alcp15 MGI:MGI:1858394 +109503 Alcp17 MGI:MGI:1858396 +109504 Alcp18 MGI:MGI:1858397 +109505 Alcp21 MGI:MGI:1858400 +109506 Alcp23 MGI:MGI:1858402 +109507 Alcp6 MGI:MGI:1858455 +109508 Alcp8 MGI:MGI:1858457 +109509 Sle4 MGI:MGI:1100862 +109510 Sle6 MGI:MGI:1353465 +109511 Alcp10 MGI:MGI:1858389 +109512 Alcp13 MGI:MGI:1858392 +109513 Alcp14 MGI:MGI:1858393 +109514 Sle5 MGI:MGI:1100858 +109515 Alcp16 MGI:MGI:1858395 +109516 Alcp19 MGI:MGI:1858398 +109517 Alcp20 MGI:MGI:1858399 +109518 Alcp22 MGI:MGI:1858401 +109519 Alcp24 MGI:MGI:1858403 +109520 Abhr1 MGI:MGI:1888528 +109521 Abhr2 MGI:MGI:1888529 +109522 Htas4 MGI:MGI:99929 +109523 Htas3 MGI:MGI:99930 +109524 Htas2 MGI:MGI:99931 +109525 Nidd3n MGI:MGI:1355301 +109526 Nidd2n MGI:MGI:1355273 +109527 Nidd1n MGI:MGI:1355320 +109528 Lrdm1 MGI:MGI:106097 +109529 Lrdm2 MGI:MGI:106093 +109530 Mhsvr1 MGI:MGI:1346092 +109531 Laq1 MGI:MGI:1278337 +109532 Eae18 MGI:MGI:1345096 +109533 Tanidd1 MGI:MGI:1932199 +109534 Tanidd2 MGI:MGI:1932200 +109535 Tanidd3 MGI:MGI:1932201 +109536 Mnek1c MGI:MGI:1858513 +109537 Mnek1a MGI:MGI:1858512 +109538 Tmevd4 MGI:MGI:1289202 +109539 Tmevd3 MGI:MGI:1289246 +109540 Re MGI:MGI:97888 +109541 Hk MGI:MGI:96102 +109542 Rn MGI:MGI:97942 +109543 Li MGI:MGI:96786 +109544 N MGI:MGI:97277 +109545 Crm MGI:MGI:88510 +109546 Och MGI:MGI:97400 +109547 Q MGI:MGI:97832 +109548 Bld MGI:MGI:88168 +109550 Gs MGI:MGI:95839 +109551 In(15)4H MGI:MGI:96678 +109552 Sri MGI:MGI:98419|Ensembl:ENSMUSG00000003161|Vega:OTTMUSG00000025793 +109553 Whl MGI:MGI:103024 +109555 Pt MGI:MGI:97790 +109556 Sha MGI:MGI:98293 +109559 Scr MGI:MGI:98256 +109560 Tal MGI:MGI:98479 +109562 Stpy MGI:MGI:1202297 +109565 Sig MGI:MGI:98305 +109568 Rn7s6 MGI:MGI:97956 +109569 Rn7s8 MGI:MGI:97957 +109571 Es8 MGI:MGI:95447 +109572 Hm MGI:MGI:96110 +109573 Rw MGI:MGI:98213 +109575 Tbx10 MGI:MGI:1261436|Ensembl:ENSMUSG00000037477 +109576 Bey MGI:MGI:1276118 +109577 Ssq MGI:MGI:1338063 +109578 Dbf MGI:MGI:94863 +109579 Es2 MGI:MGI:95431 +109580 Es5 MGI:MGI:95444 +109581 Es6 MGI:MGI:95445 +109582 Es7 MGI:MGI:95446 +109583 Es9 MGI:MGI:95448 +109584 Far MGI:MGI:95483 +109585 Paf MGI:MGI:97472 +109587 Wc MGI:MGI:98945 +109590 Es3 MGI:MGI:95442 +109591 Prt4 MGI:MGI:97779 +109592 Prt5 MGI:MGI:97780 +109593 Lmo3 MGI:MGI:102810|Ensembl:ENSMUSG00000030226|Vega:OTTMUSG00000034595 +109594 Lmo1 MGI:MGI:102812|Ensembl:ENSMUSG00000036111|Vega:OTTMUSG00000060098 +109599 Om MGI:MGI:97434 +109600 Ve MGI:MGI:98928 +109602 Uncv MGI:MGI:1261908 +109603 Es11 MGI:MGI:95422 +109604 Es12 MGI:MGI:95423 +109605 Es13 MGI:MGI:95424 +109606 Es14 MGI:MGI:95425 +109607 Es16 MGI:MGI:95427 +109608 Esa4 MGI:MGI:95428 +109609 Es23 MGI:MGI:95433 +109610 Es25 MGI:MGI:95437 +109611 Es26 MGI:MGI:95438 +109612 Es28 MGI:MGI:95440 +109613 Es29 MGI:MGI:95441 +109614 Es30 MGI:MGI:95443 +109615 Fcr MGI:MGI:95501 +109616 Pepc MGI:MGI:97541 +109618 Ubb1 MGI:MGI:105936 +109620 Dsp MGI:MGI:109611|Ensembl:ENSMUSG00000054889|Vega:OTTMUSG00000032599 +109621 Ccua MGI:MGI:1330273 +109622 Ccub1 MGI:MGI:3621712 +109623 Bhd MGI:MGI:88160 +109624 Cald1 MGI:MGI:88250|Ensembl:ENSMUSG00000029761|Vega:OTTMUSG00000014795 +109625 Es18 MGI:MGI:95429 +109627 Ins3-ps MGI:MGI:96574 +109628 Pepb MGI:MGI:97540 +109636 Pre2 MGI:MGI:97755 +109637 Upk1a MGI:MGI:98911|Ensembl:ENSMUSG00000006313|Vega:OTTMUSG00000059366 +109639 Cd24b MGI:MGI:88324 +109641 Ps MGI:MGI:97782 +109642 Tsz1 MGI:MGI:98862 +109643 Ym MGI:MGI:99149 +109644 Chol2 MGI:MGI:99483 +109647 For5 MGI:MGI:95573 +109648 Npy MGI:MGI:97374|Ensembl:ENSMUSG00000029819|Vega:OTTMUSG00000034262 +109649 Chol1 MGI:MGI:99482 +109650 Lepq1 MGI:MGI:1889232 +109651 Tl MGI:MGI:1927233 +109652 Acy1 MGI:MGI:87913|Ensembl:ENSMUSG00000023262|Vega:OTTMUSG00000049425 +109653 Bda MGI:MGI:88143 +109654 Cd24c MGI:MGI:88325 +109655 Hye MGI:MGI:96301 +109656 Lop4 MGI:MGI:96810 +109658 Txlna MGI:MGI:105968|Ensembl:ENSMUSG00000053841|Vega:OTTMUSG00000009521 +109660 Ctrl MGI:MGI:88558|Ensembl:ENSMUSG00000031896|Vega:OTTMUSG00000062063 +109661 Ds MGI:MGI:94929 +109663 Hoxc11 MGI:MGI:96193|Ensembl:ENSMUSG00000001656|Vega:OTTMUSG00000035144 +109664 Mod1r MGI:MGI:97044 +109666 Skn2 MGI:MGI:98312 +109667 Brp1 MGI:MGI:88194 +109669 Hrt1 MGI:MGI:96229 +109672 Cyb5a MGI:MGI:1926952|Ensembl:ENSMUSG00000024646|Vega:OTTMUSG00000030922 +109674 Ampd2 MGI:MGI:88016|Ensembl:ENSMUSG00000027889|Vega:OTTMUSG00000007186 +109675 Brp8 MGI:MGI:88204 +109676 Ank2 MGI:MGI:88025|Ensembl:ENSMUSG00000032826|Vega:OTTMUSG00000043348 +109677 Eox1 MGI:MGI:95398 +109678 Os MGI:MGI:97446 +109679 Ppr1 MGI:MGI:97752 +109685 Hyal3 MGI:MGI:1330288|Ensembl:ENSMUSG00000036091|Vega:OTTMUSG00000028837 +109686 Brp13 MGI:MGI:88197 +109687 Ir2 MGI:MGI:96584 +109689 Arrb1 MGI:MGI:99473|Ensembl:ENSMUSG00000018909|Vega:OTTMUSG00000034019 +109690 Ir9 MGI:MGI:99633 +109695 Ath3 MGI:MGI:88100 +109696 Ath6 MGI:MGI:88101 +109697 Cpa1 MGI:MGI:88478|Ensembl:ENSMUSG00000054446|Vega:OTTMUSG00000014402 +109698 Dh MGI:MGI:94889 +109699 Ir5 MGI:MGI:96587 +109700 Itga1 MGI:MGI:96599|Ensembl:ENSMUSG00000042284 +109701 Spla1 MGI:MGI:98382 +109702 Knsl2b MGI:MGI:98652 +109705 n-TCgca40 MGI:MGI:4413807 +109708 Lbt1 MGI:MGI:96753 +109709 Lith1 MGI:MGI:102584 +109711 Actn1 MGI:MGI:2137706|Ensembl:ENSMUSG00000015143 +109715 Len1 MGI:MGI:96771 +109717 Pol6 MGI:MGI:97736 +109718 Pol7 MGI:MGI:97737 +109719 Pol8 MGI:MGI:97738 +109720 Pol9 MGI:MGI:97739 +109721 Rasl6 MGI:MGI:97873 +109726 Bcga MGI:MGI:88136 +109727 Hst1 MGI:MGI:96258 +109728 Hst4 MGI:MGI:96261 +109729 Hst6 MGI:MGI:96263 +109730 Lyr MGI:MGI:96893 +109731 Maob MGI:MGI:96916|Ensembl:ENSMUSG00000040147|Vega:OTTMUSG00000016927 +109732 Mcr MGI:MGI:96944 +109733 Rasl4 MGI:MGI:97870 +109735 War MGI:MGI:98944 +109737 Hst7 MGI:MGI:109513 +109738 Cat4 MGI:MGI:88040 +109740 H1 MGI:MGI:95882 +109741 H3 MGI:MGI:95977 +109742 H7 MGI:MGI:96006 +109743 Hst5 MGI:MGI:96262 +109745 Lsr1 MGI:MGI:96833 +109747 Rasl3 MGI:MGI:97869 +109748 Cat5 MGI:MGI:98786 +109749 Szf1 MGI:MGI:99539 +109750 Lamr9 MGI:MGI:107957 +109751 Act7 MGI:MGI:87901 +109752 Cat3 MGI:MGI:88273 +109753 Sfat MGI:MGI:894677 +109754 Cyb5r3 MGI:MGI:94893|Ensembl:ENSMUSG00000018042|Vega:OTTMUSG00000030694 +109755 Es5r MGI:MGI:95450 +109756 H8 MGI:MGI:96007 +109757 Hya MGI:MGI:96296 +109758 Ntp MGI:MGI:97382 +109759 Pol10 MGI:MGI:97727 +109760 Pol15 MGI:MGI:97728 +109761 Pol19 MGI:MGI:97731 +109762 Pol20 MGI:MGI:97732 +109763 Pol23 MGI:MGI:97733 +109764 Pol26 MGI:MGI:97734 +109765 Etn2 MGI:MGI:5502906 +109766 Tcp3 MGI:MGI:98545 +109767 Tcp4 MGI:MGI:98546 +109768 Tcp5 MGI:MGI:98547 +109769 Tcp6 MGI:MGI:98548 +109770 Tcp7 MGI:MGI:98549 +109771 Tcp8 MGI:MGI:98550 +109772 Tcp9 MGI:MGI:98551 +109773 Prot MGI:MGI:107578 +109774 Lamr10 MGI:MGI:107951 +109776 Act1 MGI:MGI:87897 +109777 Act6 MGI:MGI:87900 +109778 Blvra MGI:MGI:88170|Ensembl:ENSMUSG00000001999|Vega:OTTMUSG00000016013 +109779 H22 MGI:MGI:95969 +109781 Ly7 MGI:MGI:96883 +109782 Mph1 MGI:MGI:97074 +109785 Pgm3 MGI:MGI:97566|Ensembl:ENSMUSG00000056131|Vega:OTTMUSG00000045044 +109786 Upg2 MGI:MGI:98910 +109788 Egm1 MGI:MGI:1261421 +109789 Act2 MGI:MGI:87898 +109790 Act5 MGI:MGI:87899 +109791 Clps MGI:MGI:88421|Ensembl:ENSMUSG00000024225|Vega:OTTMUSG00000024251 +109792 Coc MGI:MGI:88442 +109794 Cyx MGI:MGI:88614 +109796 Ea1 MGI:MGI:95263 +109797 Ea6 MGI:MGI:95269 +109798 Ea9 MGI:MGI:95272 +109801 Glo1 MGI:MGI:95742|Ensembl:ENSMUSG00000024026 +109803 Gv2 MGI:MGI:95878 +109804 H15 MGI:MGI:95887 +109805 H16 MGI:MGI:95888 +109806 H18 MGI:MGI:95890 +109807 H20 MGI:MGI:95967 +109808 H21 MGI:MGI:95968 +109809 H23 MGI:MGI:95970 +109810 H24 MGI:MGI:95971 +109811 H42 MGI:MGI:95989 +109812 H44 MGI:MGI:95991 +109813 H45 MGI:MGI:95992 +109814 H46 MGI:MGI:95993 +109815 Selenos MGI:MGI:95994|Ensembl:ENSMUSG00000075701|Vega:OTTMUSG00000021140 +109816 H49 MGI:MGI:95996 +109817 H54 MGI:MGI:96001 +109818 Hom1 MGI:MGI:96167 +109819 Mr66-2 MGI:MGI:97140 +109820 Pgc MGI:MGI:98909|Ensembl:ENSMUSG00000023987|Vega:OTTMUSG00000018356 +109821 F11 MGI:MGI:99481|Ensembl:ENSMUSG00000031645|Vega:OTTMUSG00000061128 +109822 Gig MGI:MGI:102557 +109823 Aldr3 MGI:MGI:105041 +109824 Tlf MGI:MGI:109546 +109825 Brm1 MGI:MGI:1201377 +109826 Tli1 MGI:MGI:1338021 +109828 C7 MGI:MGI:88235|Ensembl:ENSMUSG00000079105 +109829 Ea4 MGI:MGI:95267 +109830 Erp1 MGI:MGI:95417 +109831 Gv1 MGI:MGI:95877 +109832 H25 MGI:MGI:95972 +109833 H30 MGI:MGI:95978 +109834 H31 MGI:MGI:95979 +109835 H32 MGI:MGI:95980 +109836 H33 MGI:MGI:95981 +109837 H43 MGI:MGI:95990 +109838 H51 MGI:MGI:95998 +109839 Lvp1 MGI:MGI:96854 +109840 Ly11 MGI:MGI:96857 +109841 Ly14 MGI:MGI:96859 +109842 Ly20 MGI:MGI:96862 +109843 Ly23 MGI:MGI:96863 +109844 Ly25 MGI:MGI:96864 +109845 Ly29 MGI:MGI:96867 +109846 Ly31 MGI:MGI:96869 +109847 Mr66-1 MGI:MGI:97139 +109848 Mr66-3 MGI:MGI:97141 +109849 Zfp4 MGI:MGI:99184 +109850 Pctm MGI:MGI:103069 +109852 H39 MGI:MGI:106031 +109853 Lyr2 MGI:MGI:106640 +109854 Brm2 MGI:MGI:1201376 +109855 Aldr5 MGI:MGI:1276518 +109857 Cbr3 MGI:MGI:1309992|Ensembl:ENSMUSG00000022947|Vega:OTTMUSG00000019916 +109858 H61 MGI:MGI:1351672 +109859 Ads1 MGI:MGI:87943 +109860 Ads3 MGI:MGI:87945 +109861 Aft MGI:MGI:87954 +109862 Jsr MGI:MGI:96643 +109863 Ly18 MGI:MGI:96861 +109864 Ly28 MGI:MGI:96866 +109865 Ly33 MGI:MGI:96870 +109866 Ly34 MGI:MGI:96871 +109867 Ly39 MGI:MGI:96873 +109868 Rrv1 MGI:MGI:98187 +109869 Tcd1a MGI:MGI:98499 +109870 Tcd3 MGI:MGI:98501 +109871 Tcd4 MGI:MGI:98502 +109872 Thy2 MGI:MGI:98748 +109873 Tthy MGI:MGI:98863 +109877 Lyr3 MGI:MGI:107724 +109879 Akp4 MGI:MGI:87985 +109880 Braf MGI:MGI:88190|Ensembl:ENSMUSG00000002413|Vega:OTTMUSG00000035245 +109881 Mott1 MGI:MGI:892994 +109882 Ea10 MGI:MGI:95264 +109884 Lyb4 MGI:MGI:96887 +109886 Tcd5 MGI:MGI:98503 +109889 Mzf1 MGI:MGI:107457|Ensembl:ENSMUSG00000030380|Vega:OTTMUSG00000043333 +109897 Cypr2 MGI:MGI:1333846 +109898 Uvbs1 MGI:MGI:1343118 +109899 Akp1 MGI:MGI:87982 +109900 Asl MGI:MGI:88084|Ensembl:ENSMUSG00000025533|Vega:OTTMUSG00000033763 +109901 Cela1 MGI:MGI:95314|Ensembl:ENSMUSG00000023031 +109902 Esl1 MGI:MGI:95449 +109903 Ht5 MGI:MGI:96266 +109904 Mcf2 MGI:MGI:96932|Ensembl:ENSMUSG00000031139|Vega:OTTMUSG00000018385 +109905 Rap1a MGI:MGI:97852|Ensembl:ENSMUSG00000068798|Vega:OTTMUSG00000053159 +109906 Rig1 MGI:MGI:97920 +109907 Tpre MGI:MGI:98814 +109909 Zfp55 MGI:MGI:99202 +109910 Zfp91 MGI:MGI:104854|Ensembl:ENSMUSG00000024695|Vega:OTTMUSG00000034852 +109912 Ltp MGI:MGI:107786 +109918 Cypr1 MGI:MGI:1333847 +109920 Ccd MGI:MGI:88291 +109928 Rmcf MGI:MGI:97933 +109929 Zbtb25 MGI:MGI:99197|Ensembl:ENSMUSG00000056459|Vega:OTTMUSG00000041999 +109931 Tex1 MGI:MGI:102466 +109934 Abr MGI:MGI:107771|Ensembl:ENSMUSG00000017631|Vega:OTTMUSG00000006233 +109935 Dmp2 MGI:MGI:108549 +109936 Olfr40 MGI:MGI:1313144 +109938 Eis1 MGI:MGI:892031 +109939 Prpl3 MGI:MGI:892981 +109940 Hma MGI:MGI:96111 +109941 Sgp1 MGI:MGI:98290 +109944 Tex4 MGI:MGI:105929 +109945 Tex3 MGI:MGI:105930 +109947 Zfp134 MGI:MGI:107884 +109948 Zfp132 MGI:MGI:107885 +109949 Alan1 MGI:MGI:1861672 +109950 Apk MGI:MGI:88045 +109952 Ht16 MGI:MGI:96265 +109953 Map1 MGI:MGI:96917 +109954 P1Ehs1 MGI:MGI:97455 +109955 P5Ehs1 MGI:MGI:97465 +109956 P7Ehs1 MGI:MGI:97466 +109957 P9Ehs1 MGI:MGI:97467 +109958 Hfh5 MGI:MGI:99900 +109959 Amy2a5 MGI:MGI:88020|Ensembl:ENSMUSG00000074268|Vega:OTTMUSG00000022434 +109961 Rmp4 MGI:MGI:104795 +109962 Life1 MGI:MGI:1276120 +109963 Fre2 MGI:MGI:894691 +109964 Gas4 MGI:MGI:95658 +109965 Ggm1 MGI:MGI:95702 +109968 Pj1 MGI:MGI:97589 +109970 Rmp3 MGI:MGI:97936 +109971 Rua MGI:MGI:98206 +109972 Hfh6 MGI:MGI:99899 +109975 Plcd2 MGI:MGI:107449 +109976 Til1 MGI:MGI:107517 +109978 Art4 MGI:MGI:1202710|Ensembl:ENSMUSG00000030217|Vega:OTTMUSG00000027072 +109979 Art3 MGI:MGI:1202729|Ensembl:ENSMUSG00000034842|Vega:OTTMUSG00000028687 +109982 Lamr1l MGI:MGI:1930580 +109983 Ce2 MGI:MGI:88364 +109986 Pat MGI:MGI:97484 +109988 Ri1 MGI:MGI:97917 +109989 Ri2 MGI:MGI:97918 +109990 Saac MGI:MGI:98225 +109997 Tsp4 MGI:MGI:107627 +110001 Dgsh MGI:MGI:892009 +110002 Dgsb MGI:MGI:892868 +110003 Pfn1-rs MGI:MGI:895150 +110004 Dvb11-1 MGI:MGI:94938 +110005 Gas10 MGI:MGI:95656 +110006 Gusb MGI:MGI:95872|Ensembl:ENSMUSG00000025534|Vega:OTTMUSG00000024068 +110007 Qui MGI:MGI:97839 +110009 Sxa MGI:MGI:98456 +110010 Tind MGI:MGI:98755 +110011 Cfm1 MGI:MGI:106062 +110012 Tpgs1 MGI:MGI:106618|Ensembl:ENSMUSG00000020308 +110013 Lci MGI:MGI:107499 +110014 Tsp3 MGI:MGI:107635 +110015 Tsp8 MGI:MGI:109405 +110021 Dvb11-2 MGI:MGI:94939 +110022 Dvb11-3 MGI:MGI:94940 +110023 Ex MGI:MGI:95463 +110024 H58 MGI:MGI:96004 +110025 Rrsv MGI:MGI:98186 +110026 Krd MGI:MGI:99258 +110027 Cpu3 MGI:MGI:99850 +110028 Iva2 MGI:MGI:104789 +110029 Iva1 MGI:MGI:104792 +110030 Msmr2 MGI:MGI:107710 +110031 Msmr1 MGI:MGI:107712 +110032 Kif22-ps MGI:MGI:109206 +110033 Kif22 MGI:MGI:109233|Ensembl:ENSMUSG00000030677|Vega:OTTMUSG00000058381 +110036 Agp1 MGI:MGI:87958 +110037 Agp2 MGI:MGI:87959 +110038 Agp3 MGI:MGI:87960 +110039 H59 MGI:MGI:96005 +110040 Mis2 MGI:MGI:96992 +110041 Mse1 MGI:MGI:97165 +110042 Qdm MGI:MGI:97835 +110044 Hrs3 MGI:MGI:102719 +110045 Ccw MGI:MGI:107542 +110046 Kifc4a MGI:MGI:109180 +110047 Kifc4c MGI:MGI:109190 +110048 Kifc4b MGI:MGI:109197 +110049 Lmr2 MGI:MGI:1277141 +110050 Tsp9 MGI:MGI:1342300 +110051 Kis1 MGI:MGI:1355300 +110052 Dek MGI:MGI:1926209|Ensembl:ENSMUSG00000021377|Vega:OTTMUSG00000024779 +110053 Dsi1 MGI:MGI:94932 +110054 Gt10 MGI:MGI:95869 +110055 Sas2 MGI:MGI:98232 +110056 Tks MGI:MGI:98765 +110057 Pad2 MGI:MGI:104620 +110058 Syt17 MGI:MGI:104966|Ensembl:ENSMUSG00000058420|Vega:OTTMUSG00000057261 +110059 Lmr1 MGI:MGI:1277203 +110061 Gsh3 MGI:MGI:95844 +110063 Gvh MGI:MGI:95879 +110064 Rgv1 MGI:MGI:97909 +110065 Soa MGI:MGI:98349 +110066 Tcrd MGI:MGI:98611 +110067 Tcrg MGI:MGI:98623 +110069 Pad3 MGI:MGI:107866 +110070 Tubb-rs MGI:MGI:107954 +110071 Pad5 MGI:MGI:1097704 +110072 Pad4 MGI:MGI:1201404 +110074 Dut MGI:MGI:1346051|Ensembl:ENSMUSG00000027203|Vega:OTTMUSG00000015344 +110075 Bmp3 MGI:MGI:88179|Ensembl:ENSMUSG00000029335|Vega:OTTMUSG00000053551 +110076 Emb-rs3 MGI:MGI:95322 +110077 Htf9 MGI:MGI:96268 +110078 Pygb MGI:MGI:97828|Ensembl:ENSMUSG00000033059|Vega:OTTMUSG00000015772 +110079 Rep2 MGI:MGI:97901 +110080 Tme MGI:MGI:98772 +110081 Yb2 MGI:MGI:106634 +110082 Dnah5 MGI:MGI:107718|Ensembl:ENSMUSG00000022262|Vega:OTTMUSG00000026038 +110083 Dnah12 MGI:MGI:107720|Ensembl:ENSMUSG00000021879|Vega:OTTMUSG00000032533 +110084 Dnah1 MGI:MGI:107721|Ensembl:ENSMUSG00000019027 +110086 Tcpm1 MGI:MGI:108026 +110093 Nil MGI:MGI:97343 +110094 Phka2 MGI:MGI:97577|Ensembl:ENSMUSG00000031295|Vega:OTTMUSG00000019587 +110095 Pygl MGI:MGI:97829|Ensembl:ENSMUSG00000021069|Vega:OTTMUSG00000025904 +110096 Rasl2-2 MGI:MGI:97863 +110097 Rasl2-4 MGI:MGI:97865 +110098 Rasl2-5 MGI:MGI:97866 +110099 Rasl2-7 MGI:MGI:97868 +110100 Rasl5-2 MGI:MGI:97872 +110101 Rfv1 MGI:MGI:97905 +110102 Rfv2 MGI:MGI:97906 +110106 Ht6.9 MGI:MGI:103214 +110109 Nop2 MGI:MGI:107891|Ensembl:ENSMUSG00000038279|Vega:OTTMUSG00000056703 +110112 Acf1 MGI:MGI:87875 +110113 Aia1 MGI:MGI:87973 +110114 Cxv2 MGI:MGI:88572 +110115 Cyp11b1 MGI:MGI:88583|Ensembl:ENSMUSG00000075604|Vega:OTTMUSG00000045157 +110119 Mpi MGI:MGI:97075|Ensembl:ENSMUSG00000032306|Vega:OTTMUSG00000033819 +110120 Rasl2-3 MGI:MGI:97864 +110121 Serpina3kr MGI:MGI:98379 +110124 Tsu MGI:MGI:98859 +110125 Ifi15 MGI:MGI:102637 +110126 Rn18s-rs2 MGI:MGI:107305 +110127 Rn18s-rs1 MGI:MGI:107310 +110129 Cklc4 MGI:MGI:1891392 +110130 Cxv1 MGI:MGI:88571 +110131 H2-Ke1 MGI:MGI:95907 +110132 Rmv1 MGI:MGI:97938 +110133 Rmv2 MGI:MGI:97939 +110134 Rmv3 MGI:MGI:97940 +110135 Fgb MGI:MGI:99501|Ensembl:ENSMUSG00000033831|Vega:OTTMUSG00000051804 +110137 Tlag1 MGI:MGI:101804 +110138 Ccs1 MGI:MGI:102555 +110140 Rn18s-rs7 MGI:MGI:107213 +110141 Rn18s-rs6 MGI:MGI:107219 +110142 Rn18s-rs4 MGI:MGI:107275 +110143 Rn18s-rs3 MGI:MGI:107276 +110147 Ehmt2 MGI:MGI:2148922|Ensembl:ENSMUSG00000013787|Vega:OTTMUSG00000016295 +110150 Fim3 MGI:MGI:95535 +110151 H2-Ke5 MGI:MGI:95910 +110152 Hilda MGI:MGI:96089 +110153 Vis1 MGI:MGI:96091 +110154 Ifi201 MGI:MGI:96426 +110155 Igk-Pc MGI:MGI:96498 +110157 Raf1 MGI:MGI:97847|Ensembl:ENSMUSG00000000441|Vega:OTTMUSG00000020697 +110158 Si-r MGI:MGI:98302 +110159 Gct4 MGI:MGI:98356 +110162 Tctex6 MGI:MGI:98650 +110163 Tctex8 MGI:MGI:98653 +110164 Tctex9 MGI:MGI:98654 +110165 Tel-rs1 MGI:MGI:99681 +110166 Tpe1 MGI:MGI:103146 +110168 Gpr18 MGI:MGI:107859|Ensembl:ENSMUSG00000050350 +110169 Npm1-rs MGI:MGI:107880 +110171 Tsri MGI:MGI:1277125 +110172 Slc35b1 MGI:MGI:1343133|Ensembl:ENSMUSG00000020873|Vega:OTTMUSG00000001658 +110173 Manba MGI:MGI:88175|Ensembl:ENSMUSG00000028164|Vega:OTTMUSG00000030307 +110174 Fim1 MGI:MGI:95534 +110175 Ggct MGI:MGI:95700|Ensembl:ENSMUSG00000002797|Vega:OTTMUSG00000023525 +110176 Hh1 MGI:MGI:96084 +110177 His2 MGI:MGI:96092 +110178 Igh-Np MGI:MGI:96464 +110179 Igh-Pc MGI:MGI:96470 +110180 Npp MGI:MGI:97366 +110181 Xlr1 MGI:MGI:98977 +110182 Penk-rs MGI:MGI:104628 +110183 Rn18s-rs5 MGI:MGI:107222 +110185 Cinda2 MGI:MGI:1096554 +110186 Tel-rs7 MGI:MGI:1101777 +110187 Scgb2b26 MGI:MGI:87864|Ensembl:ENSMUSG00000066586|Vega:OTTMUSG00000008377 +110188 Fvis1 MGI:MGI:95536 +110189 Hkr1 MGI:MGI:96105 +110192 Tam1 MGI:MGI:98482 +110193 Tcrb-D MGI:MGI:98580 +110194 Xlr2 MGI:MGI:98978 +110195 Gtpc MGI:MGI:99637 +110196 Fdps MGI:MGI:104888|Ensembl:ENSMUSG00000059743|Vega:OTTMUSG00000052591 +110197 Dgkg MGI:MGI:105060|Ensembl:ENSMUSG00000022861|Vega:OTTMUSG00000024858 +110198 Akr7a5 MGI:MGI:107796|Ensembl:ENSMUSG00000028743|Vega:OTTMUSG00000009905 +110199 Rapop4 MGI:MGI:1194920 +110202 Aecp MGI:MGI:87949 +110204 Gma3 MGI:MGI:95763 +110205 Igk-Ef2 MGI:MGI:96496 +110206 Mlvi2 MGI:MGI:97001 +110207 Nel1 MGI:MGI:97304 +110208 Pgd MGI:MGI:97553|Ensembl:ENSMUSG00000028961|Vega:OTTMUSG00000010934 +110209 Tctex10 MGI:MGI:98644 +110210 Tctex11 MGI:MGI:98645 +110211 Tctex12 MGI:MGI:98646 +110212 Xic MGI:MGI:98972 +110213 Tmbim6 MGI:MGI:99682|Ensembl:ENSMUSG00000023010|Vega:OTTMUSG00000034310 +110214 Aod1 MGI:MGI:103026 +110215 Mml1 MGI:MGI:105375 +110216 Scfr1 MGI:MGI:106101 +110217 Tsil MGI:MGI:107442 +110219 Vas1 MGI:MGI:1274783 +110220 Igh-Aa1 MGI:MGI:96451 +110221 Igh-Aa2 MGI:MGI:96452 +110222 Igh-Aa3 MGI:MGI:96453 +110223 Igh-Ars MGI:MGI:96454 +110224 Igh-Bgl MGI:MGI:96455 +110225 Igh-Dex MGI:MGI:96458 +110226 Igh-Gte MGI:MGI:96459 +110227 Igh-Inu MGI:MGI:96460 +110228 Igh-Lev MGI:MGI:96462 +110229 Igh-Nbp MGI:MGI:96463 +110230 Igh-Ns1 MGI:MGI:96465 +110231 Igh-Ns2 MGI:MGI:96466 +110232 Igh-Ns3 MGI:MGI:96467 +110233 Igh-Ns4 MGI:MGI:96468 +110234 Igh-Ns5 MGI:MGI:96469 +110235 Igh-Sa2 MGI:MGI:96472 +110236 Igh-Sa3 MGI:MGI:96473 +110237 Igh-Sa4 MGI:MGI:96474 +110238 Igh-Sa5 MGI:MGI:96475 +110239 Igh-Src MGI:MGI:96476 +110240 Mlvi4 MGI:MGI:97003 +110241 Is(In8B2-8B3.1;6C1)1Tshir MGI:MGI:97926 +110249 Myo1f-rs1 MGI:MGI:107707 +110250 Hvmt1 MGI:MGI:1195959 +110251 Papg1 MGI:MGI:1197516 +110252 Lvis2 MGI:MGI:1347013 +110253 Triobp MGI:MGI:1349410|Ensembl:ENSMUSG00000033088|Vega:OTTMUSG00000023632 +110254 Crl1 MGI:MGI:88509 +110255 Tir3 MGI:MGI:892964 +110256 Tir2 MGI:MGI:892965 +110257 Hba-a2 MGI:MGI:96016|Ensembl:ENSMUSG00000069917|Vega:OTTMUSG00000005376 +110258 Hh3 MGI:MGI:96085 +110259 Hnl MGI:MGI:96164 +110261 Tcrd-D MGI:MGI:98613 +110262 Tel4q MGI:MGI:98692 +110263 Tel9q MGI:MGI:98702 +110264 TelYp MGI:MGI:98708 +110265 Msra MGI:MGI:106916|Ensembl:ENSMUSG00000054733|Vega:OTTMUSG00000060968 +110267 Ftl1-rs8 MGI:MGI:1201392 +110268 Ftl1-rs3 MGI:MGI:1201393 +110269 Ftl1-rs2 MGI:MGI:1201394 +110270 Ftl1-rs1 MGI:MGI:1201395 +110271 Ftl1-rs5 MGI:MGI:1201398 +110272 Ftl1-rs4 MGI:MGI:1201399 +110273 Nba2 MGI:MGI:1278323 +110274 Lvis1 MGI:MGI:1334266 +110275 Lvis4 MGI:MGI:1347011 +110276 Lvis3 MGI:MGI:1347012 +110279 Bcr MGI:MGI:88141|Ensembl:ENSMUSG00000009681 +110280 Ctl1 MGI:MGI:88551 +110281 Ctl2 MGI:MGI:88552 +110282 Ctt1 MGI:MGI:88565 +110283 Tir1 MGI:MGI:892966 +110284 Es27 MGI:MGI:95439 +110285 Foc1 MGI:MGI:95567 +110287 Ldr1 MGI:MGI:96766 +110288 Mupm1 MGI:MGI:97237 +110289 Tcm MGI:MGI:98533 +110290 Tel2q MGI:MGI:98688 +110291 Ts1 MGI:MGI:98841 +110292 Ts2 MGI:MGI:98842 +110293 Aldh5 MGI:MGI:99596 +110294 Btn-rs1 MGI:MGI:103284 +110295 Bis1 MGI:MGI:104794 +110296 Ifna10 MGI:MGI:107667 +110297 Ftl1-rs9 MGI:MGI:1201391 +110298 Ftl1-rs7 MGI:MGI:1201396 +110299 Ftl1-rs6 MGI:MGI:1201397 +110301 Arp MGI:MGI:88072 +110304 Glra3 MGI:MGI:95749|Ensembl:ENSMUSG00000038257|Vega:OTTMUSG00000036483 +110305 If1 MGI:MGI:96420 +110306 Int40 MGI:MGI:96576 +110307 Int41 MGI:MGI:96577 +110308 Krt5 MGI:MGI:96702|Ensembl:ENSMUSG00000061527|Vega:OTTMUSG00000028033 +110309 Krt6 MGI:MGI:96703 +110310 Krt7 MGI:MGI:96704|Ensembl:ENSMUSG00000023039|Vega:OTTMUSG00000028023 +110311 Lsd MGI:MGI:96830 +110312 Pmch MGI:MGI:97629|Ensembl:ENSMUSG00000035383|Vega:OTTMUSG00000035176 +110315 Trbv26 MGI:MGI:98596|IMGT/GENE-DB:TRBV26 +110316 Tcrb-V5 MGI:MGI:98600 +110319 Tcrb-V8 MGI:MGI:98606 +110321 Jckm2 MGI:MGI:102752 +110322 Lts1 MGI:MGI:106186 +110323 Cox6b1 MGI:MGI:107460|Ensembl:ENSMUSG00000036751|Vega:OTTMUSG00000059367 +110324 Bis3 MGI:MGI:1197521 +110326 Tas1r1 MGI:MGI:1927505|Ensembl:ENSMUSG00000028950|Vega:OTTMUSG00000010375 +110328 Evi4 MGI:MGI:95460 +110330 Jund2 MGI:MGI:96649 +110331 Jckm1 MGI:MGI:102753 +110332 Pp2d1 MGI:MGI:3612067|Ensembl:ENSMUSG00000044957 +110333 Rmst MGI:MGI:1099806|Ensembl:ENSMUSG00000112117 +110334 Cdr3 MGI:MGI:1100884 +110336 Ftl1-rs11 MGI:MGI:1201379 +110337 Ftl1-rs10 MGI:MGI:1201388 +110338 Anth2 MGI:MGI:88028 +110340 Ped MGI:MGI:894614 +110341 Tel13q MGI:MGI:98672 +110342 Tel14q MGI:MGI:98674 +110343 Tel16q MGI:MGI:98678 +110344 Tel17q MGI:MGI:98680 +110345 Tpm3-rs4 MGI:MGI:99708 +110346 Spe2 MGI:MGI:103168 +110348 Evi7 MGI:MGI:106191 +110349 Evi6 MGI:MGI:106192 +110350 Dync2h1 MGI:MGI:107736|Ensembl:ENSMUSG00000047193|Vega:OTTMUSG00000033489 +110351 Rap1gap MGI:MGI:109338|Ensembl:ENSMUSG00000041351|Vega:OTTMUSG00000009739 +110355 Grk2 MGI:MGI:87940|Ensembl:ENSMUSG00000024858|Vega:OTTMUSG00000035343 +110357 Mod2 MGI:MGI:97045 +110367 Tcrd-V2 MGI:MGI:98616 +110368 Tcrd-V3 MGI:MGI:98617 +110369 Tcrd-V4 MGI:MGI:98618 +110370 Tcrd-V5 MGI:MGI:98619 +110371 Tcrd-V6 MGI:MGI:98621 +110372 Tcrd-V7 MGI:MGI:98622 +110373 Tpm3-rs9 MGI:MGI:99703 +110374 Tpm3-rs6 MGI:MGI:99706 +110375 Tpm3-rs5 MGI:MGI:99707 +110376 Tpm3-rs3 MGI:MGI:99709 +110378 Tpm3-rs1 MGI:MGI:99711 +110379 Sec13 MGI:MGI:99832|Ensembl:ENSMUSG00000030298|Vega:OTTMUSG00000023506 +110380 Shroom2 MGI:MGI:107194|Ensembl:ENSMUSG00000045180|Vega:OTTMUSG00000019337 +110381 Pgame2 MGI:MGI:109641 +110382 C8b MGI:MGI:88236|Ensembl:ENSMUSG00000029656|Vega:OTTMUSG00000008115 +110383 Carg1 MGI:MGI:894648 +110384 Myhs MGI:MGI:97261 +110385 Pde4c MGI:MGI:99556|Ensembl:ENSMUSG00000031842|Vega:OTTMUSG00000027334 +110386 Tpm3-rs8 MGI:MGI:99704 +110390 Mgll-rs1 MGI:MGI:1350934 +110391 Qdpr MGI:MGI:97836|Ensembl:ENSMUSG00000015806|Vega:OTTMUSG00000053872 +110392 rsl MGI:MGI:105315 +110393 Evi11 MGI:MGI:1098651 +110396 Evi17 MGI:MGI:1355280 +110397 Evi18 MGI:MGI:1355281 +110398 Evi29 MGI:MGI:1355283 +110399 Evi20 MGI:MGI:1355287 +110400 Evi23 MGI:MGI:1355288 +110401 Evi31 MGI:MGI:1355291 +110402 Evi26 MGI:MGI:1355293 +110403 Evi25 MGI:MGI:1355325 +110404 Evi24 MGI:MGI:1355327 +110405 Igf1q1 MGI:MGI:1889233 +110406 Igf1q2 MGI:MGI:1889234 +110408 Dxcp1 MGI:MGI:94874 +110409 Nmyc2 MGI:MGI:97358 +110416 Tcrd-V5T MGI:MGI:98620 +110417 Pigh MGI:MGI:99463|Ensembl:ENSMUSG00000021120 +110418 Dxcp3 MGI:MGI:99471 +110419 Txln-rs1 MGI:MGI:102652 +110420 Dis2 MGI:MGI:103233 +110421 H3b MGI:MGI:104514 +110430 Evi13 MGI:MGI:1355276 +110431 Evi14 MGI:MGI:1355277 +110432 Evi15 MGI:MGI:1355278 +110433 Evi16 MGI:MGI:1355279 +110434 Evi19 MGI:MGI:1355282 +110435 Evi28 MGI:MGI:1355284 +110436 Evi21 MGI:MGI:1355286 +110437 Evi22 MGI:MGI:1355289 +110438 Dxcp2 MGI:MGI:94875 +110441 Cora1 MGI:MGI:1333852 +110442 13.MMHAP42FLE1 MGI:MGI:1338043 +110443 31.MMHAP64FLC4 MGI:MGI:1338059 +110446 Acat1 MGI:MGI:87870|Ensembl:ENSMUSG00000032047|Vega:OTTMUSG00000036698 +110450 Lmyc2 MGI:MGI:96800 +110453 Ly6b MGI:MGI:107526 +110454 Ly6a MGI:MGI:107527|Ensembl:ENSMUSG00000075602|Vega:OTTMUSG00000045110 +110456 20.MMHAP88FLG2 MGI:MGI:1338058 +110459 Ods MGI:MGI:1890407 +110460 Acat2 MGI:MGI:87871|Ensembl:ENSMUSG00000023832|Vega:OTTMUSG00000028085 +110461 Tcra-VA10 MGI:MGI:98574 +110462 Tcra-VBMA MGI:MGI:98575 +110463 Tcra-VBMB MGI:MGI:98576 +110464 Tcra-VBWB MGI:MGI:98577 +110465 Tcrb-C MGI:MGI:98579 +110466 Tcrb-V MGI:MGI:98582 +110467 Tcra-V8.5 MGI:MGI:99712 +110468 Tcra-V8.4 MGI:MGI:99713 +110469 Tcra-V8.3 MGI:MGI:99714 +110470 Tcra-V8.2 MGI:MGI:99715 +110471 Tcra-V8.1 MGI:MGI:99716 +110472 Tcra-V7.3 MGI:MGI:99717 +110473 Tcra-V7.2 MGI:MGI:99718 +110474 Tcra-V7.1 MGI:MGI:99719 +110475 Tcra-V5.7 MGI:MGI:99720 +110476 Tcra-V5.6 MGI:MGI:99721 +110477 Tcra-V5.5 MGI:MGI:99722 +110478 Tcra-V5.4 MGI:MGI:99723 +110479 Tcra-V5.3 MGI:MGI:99724 +110480 Tcra-V5.2 MGI:MGI:99725 +110481 Tcra-V5.1 MGI:MGI:99726 +110482 Tcra-V4.9 MGI:MGI:99727 +110483 Tcra-V4.8 MGI:MGI:99728 +110484 Tcra-V4.7 MGI:MGI:99729 +110485 Tcra-V4.6 MGI:MGI:99730 +110486 Tcra-V4.5 MGI:MGI:99731 +110487 Tcra-V4.4 MGI:MGI:99732 +110488 Tcra-V4.3 MGI:MGI:99733 +110489 Tcra-V4.2 MGI:MGI:99734 +110490 Tcra-V4.1 MGI:MGI:99737 +110491 Tcra-V3.6 MGI:MGI:99738 +110492 Tcra-V3.5 MGI:MGI:99739 +110493 Tcra-V3.4 MGI:MGI:99740 +110494 Tcra-V3.3 MGI:MGI:99741 +110495 Tcra-V3.2 MGI:MGI:99742 +110496 Tcra-V3.1 MGI:MGI:99743 +110497 Tcra-V1.9 MGI:MGI:99767 +110498 Tcra-V1.8 MGI:MGI:99768 +110499 Tcra-V1.7 MGI:MGI:99769 +110500 Tcra-V1.6 MGI:MGI:99770 +110501 Tcra-V1.5 MGI:MGI:99771 +110502 Tcra-V1.4 MGI:MGI:99772 +110503 Tcra-V1.3 MGI:MGI:99773 +110504 Tcra-V1.2 MGI:MGI:99774 +110505 Tcra-V1.1 MGI:MGI:99775 +110507 Ltp-rs MGI:MGI:107762 +110508 Egr5-rs MGI:MGI:108097 +110509 Tcra-V2.7 MGI:MGI:108102 +110511 Olfr153 MGI:MGI:1313138|Ensembl:ENSMUSG00000061520|Vega:OTTMUSG00000013805 +110513 Prdx1-rs1 MGI:MGI:1859800 +110514 Prdx1-rs2 MGI:MGI:1859801 +110515 Prdx1-rs3 MGI:MGI:1859802 +110516 Prdx2-rs1 MGI:MGI:1859807 +110518 Prdx2-rs4 MGI:MGI:1859809 +110521 Hivep1 MGI:MGI:96100|Ensembl:ENSMUSG00000021366 +110522 Igl1-r MGI:MGI:96531 +110523 Tcrd-J MGI:MGI:98614 +110524 Dgkq MGI:MGI:102918|Ensembl:ENSMUSG00000004815|Vega:OTTMUSG00000026824 +110525 Mnm MGI:MGI:1332551 +110526 Prdx1-rs4 MGI:MGI:1859803 +110527 Prdx1-rs5 MGI:MGI:1859804 +110528 Prdx2-rs2 MGI:MGI:1859806 +110529 Prdx2-rs5 MGI:MGI:1859810 +110530 Prdx2-rs7 MGI:MGI:1859812 +110531 Gpx4-ps MGI:MGI:1890509 +110532 Adarb1 MGI:MGI:891999|Ensembl:ENSMUSG00000020262|Vega:OTTMUSG00000020501 +110533 Fdpsl2 MGI:MGI:95504 +110534 Fdpsl4 MGI:MGI:95506 +110535 Fdpsl9 MGI:MGI:95511 +110536 H2-D2 MGI:MGI:95897 +110537 Lfo1 MGI:MGI:96773 +110538 Lfo2 MGI:MGI:96774 +110539 Ltw3 MGI:MGI:96848 +110542 Amhr2 MGI:MGI:105062|Ensembl:ENSMUSG00000023047|Vega:OTTMUSG00000035015 +110543 Ptma-rs5 MGI:MGI:107584 +110544 Ptma-rs4 MGI:MGI:107586 +110545 Ptma-rs8 MGI:MGI:107643 +110546 Ptma-rs7 MGI:MGI:107644 +110547 Cltd-rs MGI:MGI:1202883 +110548 Fdpsl3 MGI:MGI:95505 +110549 Fdpsl5 MGI:MGI:95507 +110550 Fdpsl6 MGI:MGI:95508 +110551 Fdpsl7 MGI:MGI:95509 +110552 Fdpsl8 MGI:MGI:95510 +110553 H2-D3 MGI:MGI:95898 +110555 H2-M8-ps MGI:MGI:95920 +110557 H2-Q6 MGI:MGI:95935|Ensembl:ENSMUSG00000073409|Vega:OTTMUSG00000037190 +110558 H2-Q9 MGI:MGI:95938 +110559 H2-T2 MGI:MGI:95953 +110560 H2-T4 MGI:MGI:95960 +110561 H2-T5 MGI:MGI:95961 +110562 H2-T7 MGI:MGI:95963 +110563 H2-T8 MGI:MGI:95964 +110564 Lth1 MGI:MGI:96838 +110565 Ltw2 MGI:MGI:96847 +110569 Tcra-V4.11 MGI:MGI:99735 +110570 Tcra-V4.10 MGI:MGI:99736 +110571 Tcra-V19.2 MGI:MGI:99747 +110572 Tcra-V19.1 MGI:MGI:99748 +110573 Tcra-V15.3 MGI:MGI:99749 +110574 Tcra-V15.2 MGI:MGI:99750 +110575 Tcra-V15.1 MGI:MGI:99751 +110576 Tcra-V12.3 MGI:MGI:99752 +110577 Tcra-V12.2 MGI:MGI:99753 +110578 Tcra-V12.1 MGI:MGI:99754 +110579 Tcra-V11.6 MGI:MGI:99755 +110580 Tcra-V11.5 MGI:MGI:99756 +110581 Tcra-V11.4 MGI:MGI:99757 +110582 Tcra-V11.3 MGI:MGI:99758 +110583 Tcra-V11.2 MGI:MGI:99759 +110584 Tcra-V11.1 MGI:MGI:99760 +110585 Tcra-V10.6 MGI:MGI:99761 +110586 Tcra-V10.5 MGI:MGI:99762 +110587 Tcra-V10.4 MGI:MGI:99763 +110588 Tcra-V10.3 MGI:MGI:99764 +110589 Tcra-V10.2 MGI:MGI:99765 +110590 Tcra-V10.1 MGI:MGI:99766 +110591 Iph1 MGI:MGI:105990 +110592 Ptma-rs6 MGI:MGI:107591 +110593 Prdm2 MGI:MGI:107628|Ensembl:ENSMUSG00000057637|Vega:OTTMUSG00000010119 +110594 Tcra-V23.1 MGI:MGI:108205 +110595 Timp4 MGI:MGI:109125|Ensembl:ENSMUSG00000030317|Vega:OTTMUSG00000056615 +110596 Arhgef28 MGI:MGI:1346016|Ensembl:ENSMUSG00000021662 +110598 Cnpl MGI:MGI:88438 +110599 Fdpsl10 MGI:MGI:95503 +110601 H2-T6 MGI:MGI:95962 +110602 Kfo1 MGI:MGI:96675 +110604 Ril3 MGI:MGI:97924 +110606 Fntb MGI:MGI:1861305|Ensembl:ENSMUSG00000033373|Vega:OTTMUSG00000033888 +110608 H2-T14 MGI:MGI:95946 +110609 H2-T16 MGI:MGI:95948 +110610 Kth1 MGI:MGI:96706 +110611 Hdlbp MGI:MGI:99256|Ensembl:ENSMUSG00000034088|Vega:OTTMUSG00000048654 +110612 Iglv2 MGI:MGI:99548|IMGT/GENE-DB:IGLV2 +110613 Ptma-rs12 MGI:MGI:107607 +110614 Mrv6 MGI:MGI:107719 +110615 Ihpd MGI:MGI:1096870 +110616 Atxn3 MGI:MGI:1099442|Ensembl:ENSMUSG00000021189|Vega:OTTMUSG00000030696 +110620 H2-Q11 MGI:MGI:95930 +110621 H2-T11-ps MGI:MGI:95943 +110622 H2-T12 MGI:MGI:95944 +110623 H2-T15 MGI:MGI:95947 +110624 H2-T19 MGI:MGI:95952 +110625 H2-T20 MGI:MGI:95954 +110626 H2-T21 MGI:MGI:95955 +110628 Rip MGI:MGI:97928 +110629 Tel2p MGI:MGI:98687 +110630 Tel7p MGI:MGI:98697 +110631 H2-Q15 MGI:MGI:106048 +110632 H2-Q14 MGI:MGI:106049 +110633 H2-Q13 MGI:MGI:106050 +110634 H2-Q12 MGI:MGI:106051 +110636 Bmfr1 MGI:MGI:88172 +110637 Grik4 MGI:MGI:95817|Ensembl:ENSMUSG00000032017|Vega:OTTMUSG00000020650 +110639 Prps2 MGI:MGI:97776|Ensembl:ENSMUSG00000025742|Vega:OTTMUSG00000019570 +110640 Ripr MGI:MGI:97929 +110641 Hoxb3os MGI:MGI:103211 +110645 Paep MGI:MGI:97471 +110646 Tel4q1 MGI:MGI:107210 +110648 Lmx1a MGI:MGI:1888519|Ensembl:ENSMUSG00000026686|Vega:OTTMUSG00000020906 +110649 Idd7 MGI:MGI:96409 +110650 Mdm3 MGI:MGI:96953 +110651 Rps6ka3 MGI:MGI:104557|Ensembl:ENSMUSG00000031309|Vega:OTTMUSG00000016505 +110654 Idd2 MGI:MGI:96404 +110655 Idd3 MGI:MGI:96405 +110656 Idd5 MGI:MGI:96407 +110657 Idd8 MGI:MGI:96410 +110658 Idd9 MGI:MGI:96411 +110659 Pvrl2-rs1 MGI:MGI:97823 +110660 Scl2 MGI:MGI:98244 +110662 Seao MGI:MGI:98273 +110663 Tel13p MGI:MGI:98671 +110664 Tel14p MGI:MGI:98673 +110665 Tel16p MGI:MGI:98677 +110666 Tel17p MGI:MGI:98679 +110667 Yb1a MGI:MGI:99142 +110668 Yb1b MGI:MGI:99143 +110669 Yb1c MGI:MGI:99144 +110670 Yb1d MGI:MGI:99145 +110671 Fti1 MGI:MGI:1343203 +110673 Hbvi MGI:MGI:96030 +110674 Idd1 MGI:MGI:96400 +110675 Idd4 MGI:MGI:96406 +110677 TelXqYq1 MGI:MGI:98705 +110678 TelXqYq2 MGI:MGI:98706 +110679 TelXqYq3 MGI:MGI:98707 +110680 Top1-rs1 MGI:MGI:99429 +110681 Ssic1 MGI:MGI:103215 +110682 Cd79bl MGI:MGI:103570 +110685 Afr2 MGI:MGI:87953 +110689 Csi MGI:MGI:88536 +110690 Cyp2a MGI:MGI:88595 +110691 Hyab MGI:MGI:96297 +110692 Hydk MGI:MGI:96300 +110693 Prkch-rs2 MGI:MGI:99623 +110694 Prkch-rs1 MGI:MGI:99624 +110695 Aldh7a1 MGI:MGI:108186|Ensembl:ENSMUSG00000053644|Vega:OTTMUSG00000035214 +110696 H2-M10.3 MGI:MGI:1276524|Ensembl:ENSMUSG00000058124|Vega:OTTMUSG00000014940 +110700 Cni-rs2 MGI:MGI:1289197 +110701 Cni-rs1 MGI:MGI:1289256 +110709 Braf-rs1 MGI:MGI:88191 +110712 Idd10 MGI:MGI:96401 +110713 Idd11 MGI:MGI:96402 +110714 Mycnos MGI:MGI:97288 +110716 Idd13 MGI:MGI:99415 +110717 Top1-rs2 MGI:MGI:99468 +110718 Zfp82-rs1 MGI:MGI:107806 +110723 Cnbpl1 MGI:MGI:88432 +110724 Cnbpl2 MGI:MGI:88433 +110726 Idd12 MGI:MGI:96403 +110727 Odc-rs18 MGI:MGI:97412 +110728 Odc-rs20 MGI:MGI:97415 +110729 Odc-rs21 MGI:MGI:97416 +110732 Tex2-rs1 MGI:MGI:102464 +110733 Idd16 MGI:MGI:107544 +110734 Zfp91-rs1 MGI:MGI:109633 +110735 Idd17 MGI:MGI:1096369 +110736 Idd18 MGI:MGI:1203733 +110737 Idd19 MGI:MGI:1277191 +110738 Odc-rs17 MGI:MGI:97411 +110739 Odc-rs19 MGI:MGI:97413 +110741 Dcsx4 MGI:MGI:107512 +110742 Dcsx3 MGI:MGI:107513 +110743 Dcsx2 MGI:MGI:107514 +110744 Dcsx1 MGI:MGI:107515 +110745 Hykk1 MGI:MGI:96303 +110746 Psp-rs1 MGI:MGI:99424 +110747 Actb-rs2 MGI:MGI:107841 +110748 Zfp161-rs1 MGI:MGI:1194496 +110749 Chaf1b MGI:MGI:1314881|Ensembl:ENSMUSG00000022945|Vega:OTTMUSG00000027288 +110750 Cse1l MGI:MGI:1339951|Ensembl:ENSMUSG00000002718|Vega:OTTMUSG00000001165 +110751 Adam33 MGI:MGI:1341813|Ensembl:ENSMUSG00000027318|Vega:OTTMUSG00000015537 +110753 Amh-rs1 MGI:MGI:88007 +110754 Igkrs MGI:MGI:96521 +110755 Spe1r MGI:MGI:103173 +110756 Ngfg-rs2 MGI:MGI:107458 +110757 Ngfg-rs1 MGI:MGI:107459 +110758 Actb-rs1 MGI:MGI:107855 +110759 Igkj1 MGI:MGI:1316689|IMGT/GENE-DB:IGKJ1 +110760 Igkj2 MGI:MGI:1316690|IMGT/GENE-DB:IGKJ2 +110761 Igkj3 MGI:MGI:1316691|IMGT/GENE-DB:IGKJ3 +110762 Igkj4 MGI:MGI:1316692|IMGT/GENE-DB:IGKJ4 +110763 Igkj5 MGI:MGI:1316738|IMGT/GENE-DB:IGKJ5 +110771 Amh-rs2 MGI:MGI:88008 +110772 Amh-rs7 MGI:MGI:88013 +110773 Hsdr1 MGI:MGI:96237 +110774 Igl-C5 MGI:MGI:99856 +110777 Spe1-s MGI:MGI:103161 +110779 Hoxd3os MGI:MGI:105385 +110783 Rvil1 MGI:MGI:98212 +110784 Nr3c2 MGI:MGI:99459|Ensembl:ENSMUSG00000031618|Vega:OTTMUSG00000022950 +110785 Iglc1 MGI:MGI:99546|IMGT/GENE-DB:IGLC1 +110786 Iglc2 MGI:MGI:99547|IMGT/GENE-DB:IGLC2 +110787 Iglc3 MGI:MGI:99886|IMGT/GENE-DB:IGLC3 +110789 Adgrv1 MGI:MGI:1274784|Ensembl:ENSMUSG00000069170|Vega:OTTMUSG00000032905 +110790 Igk-V10A MGI:MGI:1298365 +110791 Igk-V10C MGI:MGI:1298403 +110792 Igk-V10B MGI:MGI:1298411 +110794 Cebpe MGI:MGI:103572|Ensembl:ENSMUSG00000052435 +110796 Tshz1 MGI:MGI:1346031|Ensembl:ENSMUSG00000046982|Vega:OTTMUSG00000040170 +110798 H2-S MGI:MGI:95939 +110799 Scom MGI:MGI:98253 +110800 Camkl MGI:MGI:99853 +110802 Pmp22-rs MGI:MGI:107900 +110803 Stop1-d MGI:MGI:1330277 +110804 Sod1m MGI:MGI:1929811 +110805 Foxe1 MGI:MGI:1353500|Ensembl:ENSMUSG00000070990|Vega:OTTMUSG00000006884 +110809 Srsf1 MGI:MGI:98283|Ensembl:ENSMUSG00000018379|Vega:OTTMUSG00000001473 +110810 Snrp2a MGI:MGI:98338 +110811 Tblvi1 MGI:MGI:98492 +110813 Igk-V9-26 MGI:MGI:96520 +110815 Stop1-p MGI:MGI:1330285 +110816 Pwp2 MGI:MGI:1341200|Ensembl:ENSMUSG00000032834 +110817 Tstap198-13 MGI:MGI:98853 +110818 Tstap198-14 MGI:MGI:98854 +110819 Tstap198-15 MGI:MGI:98855 +110821 Pcca MGI:MGI:97499|Ensembl:ENSMUSG00000041650|Vega:OTTMUSG00000025744 +110825 Gpcr19-rs2 MGI:MGI:99564 +110826 Etfb MGI:MGI:106098|Ensembl:ENSMUSG00000004610|Vega:OTTMUSG00000023293 +110829 Lims1 MGI:MGI:1195263|Ensembl:ENSMUSG00000019920|Vega:OTTMUSG00000024823 +110831 Cbx-rs1 MGI:MGI:88286 +110832 Kras2-rs1 MGI:MGI:96681 +110833 Fzd2-rs1 MGI:MGI:108548 +110834 Chrna3 MGI:MGI:87887|Ensembl:ENSMUSG00000032303|Vega:OTTMUSG00000063118 +110835 Chrna5 MGI:MGI:87889|Ensembl:ENSMUSG00000035594|Vega:OTTMUSG00000063246 +110836 Kras2-rs2 MGI:MGI:96682 +110837 Usf1-rs2 MGI:MGI:103148 +110838 Usf1-rs3 MGI:MGI:104622 +110839 Sycp1-rs3 MGI:MGI:1194913 +110840 Sycp1-rs2 MGI:MGI:1194914 +110841 Mybbp1a-rs1 MGI:MGI:1329030 +110842 Etfa MGI:MGI:106092|Ensembl:ENSMUSG00000032314|Vega:OTTMUSG00000026421 +110843 Fzd2-rs2 MGI:MGI:108500 +110845 Mybbp1a-rs2 MGI:MGI:1329029 +110848 Ahcy-rs1 MGI:MGI:87969 +110850 Tarbp2-rs1 MGI:MGI:103015 +110851 Tarbp2-rs2 MGI:MGI:103019 +110852 Adfp-ps MGI:MGI:103299 +110854 Ptpa MGI:MGI:1346006|Ensembl:ENSMUSG00000039515|Vega:OTTMUSG00000016797 +110855 Pde6c MGI:MGI:105956|Ensembl:ENSMUSG00000024992 +110856 Clns1a-rs1 MGI:MGI:109655 +110857 Snrpd-rs2 MGI:MGI:98343 +110858 Evi5-rs2 MGI:MGI:109534 +110859 Cdc42l1 MGI:MGI:1096869 +110860 Cdc42l3 MGI:MGI:1096871 +110861 Evi5-rs1 MGI:MGI:109543 +110862 Kcnq3 MGI:MGI:1336181|Ensembl:ENSMUSG00000056258|Vega:OTTMUSG00000044954 +110863 Gdc2 MGI:MGI:95680 +110864 Fert1 MGI:MGI:105927 +110869 Cirbp-rs2 MGI:MGI:108107 +110870 Cirbp-rs1 MGI:MGI:108108 +110871 Cirbp-rs3 MGI:MGI:108211 +110872 Atp6v0c-rs2 MGI:MGI:1338880 +110873 Ltrm3 MGI:MGI:96844 +110874 Ltrm4 MGI:MGI:96845 +110875 Micrl MGI:MGI:96981 +110876 Scn2a MGI:MGI:98248|Ensembl:ENSMUSG00000075318|Vega:OTTMUSG00000012963 +110877 Slc18a1 MGI:MGI:106684|Ensembl:ENSMUSG00000036330|Vega:OTTMUSG00000025652 +110878 Nova2-rs1 MGI:MGI:1100871 +110879 Ltrm1 MGI:MGI:96842 +110880 Scn4a MGI:MGI:98250|Ensembl:ENSMUSG00000001027|Vega:OTTMUSG00000003417 +110882 Ltrm2 MGI:MGI:96843 +110883 Nova2-rs3 MGI:MGI:1100872 +110884 Nova2-rs2 MGI:MGI:1100873 +110886 Gabra5 MGI:MGI:95617|Ensembl:ENSMUSG00000055078|Vega:OTTMUSG00000058873 +110887 Gsta-rs1 MGI:MGI:95858 +110888 Hivep1-rs1 MGI:MGI:96101 +110889 Cyp2b6l MGI:MGI:1316653 +110890 H2-T18rs MGI:MGI:95951 +110891 Slc8a2 MGI:MGI:107996|Ensembl:ENSMUSG00000030376|Vega:OTTMUSG00000060705 +110892 Sui1-rs2 MGI:MGI:105122 +110893 Slc8a3 MGI:MGI:107976|Ensembl:ENSMUSG00000079055|Vega:OTTMUSG00000044361 +110894 Cx3cl1-rs1 MGI:MGI:1330827 +110895 Slc9a4 MGI:MGI:105074|Ensembl:ENSMUSG00000026065|Vega:OTTMUSG00000050474 +110899 Lrp-rs MGI:MGI:108387 +110900 Atp1b3-rs MGI:MGI:1196359 +110901 Acadvl-rs1 MGI:MGI:1298376 +110902 Chrna2 MGI:MGI:87886|Ensembl:ENSMUSG00000022041|Vega:OTTMUSG00000039812 +110905 Mapk3-rs1 MGI:MGI:1096370 +110907 Hspa2os MGI:MGI:104988 +110909 Chuk-rs1 MGI:MGI:99485 +110910 Pcca-rs MGI:MGI:103120 +110911 Cds2 MGI:MGI:1332236|Ensembl:ENSMUSG00000058793|Vega:OTTMUSG00000015552 +110913 Pou5f1-rs10 MGI:MGI:102710 +110914 Fabp3-rs3 MGI:MGI:102549 +110915 Lamr1-rs2 MGI:MGI:97458 +110916 Lamr1-rs4 MGI:MGI:97459 +110917 Lamr1-rs6 MGI:MGI:97461 +110918 Lamr1-rs5 MGI:MGI:97460 +110919 Lamr1-rs7 MGI:MGI:97462 +110920 Hspa13 MGI:MGI:1309463|Ensembl:ENSMUSG00000032932|Vega:OTTMUSG00000023583 +110921 Atp1b3-rs2 MGI:MGI:1315189 +110922 Nr2e3-rs1 MGI:MGI:1859175 +110923 Tmevp2 MGI:MGI:1298383 +110924 Tmevp3 MGI:MGI:1298384 +110926 Hmgn1-rs19 MGI:MGI:893582 +110927 Hmgn1-rs18 MGI:MGI:893583 +110928 Ap3s1-rs3 MGI:MGI:1929218 +110929 Sui1-rs4 MGI:MGI:105127 +110930 Sui1-rs3 MGI:MGI:105131 +110931 Vmn2r-ps57 MGI:MGI:1351346 +110934 Mrg2-rs1 MGI:MGI:109636 +110935 Atp6v1b1 MGI:MGI:103285|Ensembl:ENSMUSG00000006269|Vega:OTTMUSG00000058015 +110937 Apbb1-rs1 MGI:MGI:1274785 +110938 Kcnd1-rs1 MGI:MGI:96672 +110940 Tmevd1 MGI:MGI:98773 +110941 Tmevd2 MGI:MGI:98774 +110942 Kcna1-rs1 MGI:MGI:96655 +110943 Kcna1-rs2 MGI:MGI:96656 +110944 Kcna1-rs3 MGI:MGI:96657 +110945 Kcna1-rs4 MGI:MGI:96658 +110946 Tceb1l-rs1 MGI:MGI:103235 +110947 Tceb1l-rs2 MGI:MGI:103230 +110948 Hlcs MGI:MGI:894646|Ensembl:ENSMUSG00000040820 +110949 Atp5g1-rs4 MGI:MGI:1261898 +110950 Atp5g1-rs5 MGI:MGI:1261899 +110951 Atp5g1-rs1 MGI:MGI:1261900 +110952 Atp5g1-rs2 MGI:MGI:1261901 +110953 Atp5g1-rs3 MGI:MGI:1261902 +110954 Rpl10 MGI:MGI:105943|Ensembl:ENSMUSG00000008682|Vega:OTTMUSG00000017647 +110956 D17H6S56E-5 MGI:MGI:1306799 +110957 D1Pas1 MGI:MGI:91842|Ensembl:ENSMUSG00000039224|Vega:OTTMUSG00000029142 +110958 M1ap MGI:MGI:1315200|Ensembl:ENSMUSG00000030041|Vega:OTTMUSG00000024060 +110959 Nudt19 MGI:MGI:94203|Ensembl:ENSMUSG00000034875|Vega:OTTMUSG00000026112 +110960 Tars MGI:MGI:106314|Ensembl:ENSMUSG00000022241 +110962 Mbd6 MGI:MGI:106378|Ensembl:ENSMUSG00000025409|Vega:OTTMUSG00000027285 +110963 D6Mit97 MGI:MGI:93731 +110964 Lamb1-2 MGI:MGI:96744 +110965 Ela1-ps MGI:MGI:95315 +110966 Rnu1-2 MGI:MGI:97968 +110967 Sdc-ps1 MGI:MGI:1349159 +110969 Ctsb-ps MGI:MGI:1346993 +110970 Ctsh-ps MGI:MGI:1346994 +110971 Klk1b12-ps MGI:MGI:892025 +110972 Anxa7-ps1 MGI:MGI:88032 +110973 Tpm4-ps MGI:MGI:107955 +110974 Kifl1-ps MGI:MGI:1861134 +110986 Ubc-rs1 MGI:MGI:1100519 +110987 Myo7b-rs1 MGI:MGI:107727 +110988 Rps2-ps1 MGI:MGI:1314662 +110989 Rnu1-ps1 MGI:MGI:97969 +110990 Rnu1-ps2 MGI:MGI:97970 +110991 Adh1-ps MGI:MGI:87923 +110992 Top1-ps2 MGI:MGI:98789 +110993 Ppi-rs MGI:MGI:108049 +110995 Tdg-ps1 MGI:MGI:108298 +110996 Rap1a-ps3 MGI:MGI:103578 +110997 Adh1-ps2 MGI:MGI:1096321 +110998 Ppia-ps1 MGI:MGI:1859626 +110999 Capza1-ps2 MGI:MGI:106218 +111000 Capza1-ps1 MGI:MGI:106236 +111001 Smad-ps1 MGI:MGI:109449 +111002 Marcksl1-ps4 MGI:MGI:97147 +111005 Marcksl1-ps1 MGI:MGI:97144 +111007 Pgk1-ps4 MGI:MGI:97559 +111008 Cbl-ps1 MGI:MGI:88280 +111009 Marcksl1-ps2 MGI:MGI:97145 +111014 Hsp86-ps3 MGI:MGI:96253 +111040 Rrm2-ps1 MGI:MGI:98182 +111041 Rrm2-ps2 MGI:MGI:98183 +111042 Hsp86-ps2 MGI:MGI:96252 +111043 Hsp86-ps4 MGI:MGI:96254 +111055 Rrm2-ps3 MGI:MGI:98184 +111056 Rrm2-ps4 MGI:MGI:98185 +111057 Ass-ps2 MGI:MGI:88089 +111058 Hsp86-ps1 MGI:MGI:96251 +111064 Msh6-rs MGI:MGI:107580 +111065 Odc-rs1 MGI:MGI:97403 +111066 Odc-rs2 MGI:MGI:97414 +111067 Odc-rs3 MGI:MGI:97417 +111068 Odc-rs4 MGI:MGI:97418 +111069 Odc-rs5 MGI:MGI:97419 +111070 Odc-rs6 MGI:MGI:97420 +111071 Odc-rs7 MGI:MGI:97421 +111072 Odc-rs9 MGI:MGI:97423 +111114 Eif3s6-ps6 MGI:MGI:103207 +111115 Eif3s6-ps5 MGI:MGI:103208 +111116 Akt2-ps MGI:MGI:108506 +111117 Kras1-ps MGI:MGI:96679 +111118 Odc-rs8 MGI:MGI:97422 +111141 Zfp82-rs2 MGI:MGI:107781 +111142 Odc-rs14 MGI:MGI:97408 +111144 Zfp86-rs2 MGI:MGI:107758 +111145 Zfp73-rs2 MGI:MGI:107759 +111146 Zfp77-rs1 MGI:MGI:107761 +111147 Zfp79-rs1 MGI:MGI:107779 +111148 Odc-rs10 MGI:MGI:97404 +111149 Odc-rs12 MGI:MGI:97406 +111150 Odc-rs13 MGI:MGI:97407 +111151 Odc-rs16 MGI:MGI:97410 +111172 Tpi-rs3 MGI:MGI:98801 +111173 Erc1 MGI:MGI:2151013|Ensembl:ENSMUSG00000030172|Vega:OTTMUSG00000044533 +111174 Taar1 MGI:MGI:2148258|Ensembl:ENSMUSG00000056379 +111175 Pecr MGI:MGI:2148199|Ensembl:ENSMUSG00000026189|Vega:OTTMUSG00000026657 +111176 pwk MGI:MGI:1351336 +111178 Ryk-ps1 MGI:MGI:103028 +111180 Zfp73-rs1 MGI:MGI:107764 +111186 Stmn1-rs1 MGI:MGI:96740 +111187 Odc-rs15 MGI:MGI:97409 +111196 Gm20551 MGI:MGI:5295658 +111205 Tpi-rs2 MGI:MGI:98800 +111208 Dhfr-rs1 MGI:MGI:101826 +111209 Hspa9-ps2 MGI:MGI:1345459 +111212 Tpi-rs6 MGI:MGI:98804 +111213 Tpi-rs7 MGI:MGI:98805 +111216 Oat-rs2 MGI:MGI:97396 +111217 Amh-rs4 MGI:MGI:88010 +111218 Mxi1-rs1 MGI:MGI:97246 +111220 Pgk1-rs5 MGI:MGI:97560 +111223 Tpi-rs11 MGI:MGI:98799 +111224 Hmgb1-rs9 MGI:MGI:104298 +111225 Sycp1-ps2 MGI:MGI:1098281 +111227 Pgk1-rs6 MGI:MGI:97561 +111228 Ppib-rs1 MGI:MGI:99464 +111229 Hmgb1-rs8 MGI:MGI:104299 +111230 Hmgb1-ps9 MGI:MGI:96115 +111232 Hmgb1-rs5 MGI:MGI:96117 +111233 Hmgb1-rs6 MGI:MGI:96118 +111234 Ppib-rs2 MGI:MGI:99465 +111236 Hras1-ps1 MGI:MGI:96225 +111237 Bmp4-ps MGI:MGI:88178 +111238 Snrpn-ps1 MGI:MGI:98348 +111239 Gabpb1-ps1 MGI:MGI:99882 +111240 Hmga1-rs2 MGI:MGI:96162 +111241 Hmga1-rs1 MGI:MGI:96161|Ensembl:ENSMUSG00000078249|Vega:OTTMUSG00000004118 +111243 Mif-ps5 MGI:MGI:103160 +111245 Mif-ps2 MGI:MGI:103165 +111246 Mcl1-rs1 MGI:MGI:101768 +111248 Mif-ps7 MGI:MGI:103171 +111249 H2-M10-ps2 MGI:MGI:1276552 +111250 H2-M10-ps3 MGI:MGI:1276551 +111251 H2-M10-ps1 MGI:MGI:1276553 +111253 Gm2a-rs1 MGI:MGI:102671 +111254 Icam1-rs1 MGI:MGI:96393 +111255 Aprt-rs2 MGI:MGI:88063 +111256 Dnaja1-ps MGI:MGI:1270127 +111257 Tek-ps MGI:MGI:104693 +111258 Snrp1a-rs2 MGI:MGI:98334 +111259 Snrp2b-rs2 MGI:MGI:98340 +111261 Snrp1a-rs1 MGI:MGI:98333 +111262 Snrp1a-rs3 MGI:MGI:98335 +111263 Snrp1a-rs4 MGI:MGI:98336 +111264 Snrp1a-rs5 MGI:MGI:98337 +111265 Snrp2a-rs3 MGI:MGI:98339 +111266 Cdc34b MGI:MGI:1858429 +111267 Acadm-ps2 MGI:MGI:102808 +111268 Acadm-ps1 MGI:MGI:106616 +111269 Hprt-ps1 MGI:MGI:96218 +111270 Srpk1-ps1 MGI:MGI:1196406 +111273 Pou5f1-rs2 MGI:MGI:101891 +111282 Ugt1a1-rs1 MGI:MGI:98899 +111283 Psmb7-ps2 MGI:MGI:1859624 +111284 Hmgn1-rs2 MGI:MGI:96128 +111285 Hmgn2-rs5 MGI:MGI:96152 +111286 Hmgn1-rs5 MGI:MGI:96131 +111287 Hmgn1-rs6 MGI:MGI:96132 +111288 Hmgn1-rs7 MGI:MGI:96133 +111289 Hmgn1-rs9 MGI:MGI:96135 +111290 Hmgn2-rs2 MGI:MGI:96148 +111291 Hmgn2-rs3 MGI:MGI:96150 +111292 Hmgn2-rs6 MGI:MGI:96153 +111293 Hmgn2-rs7 MGI:MGI:96154 +111294 Hmgn2-rs8 MGI:MGI:96155 +111295 Slc11a1-rs1 MGI:MGI:99910 +111296 Smt3h2-ps MGI:MGI:1859622 +111297 Hmgn1-rs1 MGI:MGI:96121 +111298 Hmgn1-rs3 MGI:MGI:96129 +111299 Hmgn1-rs4 MGI:MGI:96130 +111300 Hmgn1-rs8 MGI:MGI:96134 +111301 Hmgn2-rs1 MGI:MGI:96137 +111302 Hmgn2-rs4 MGI:MGI:96151 +111303 Hmgn2-rs9 MGI:MGI:96156 +111304 Ube2b-rs1 MGI:MGI:98893 +111305 Ube2b-rs2 MGI:MGI:102943 +111306 Hmgn1-rs11 MGI:MGI:96123 +111307 Hmgn1-rs13 MGI:MGI:96125 +111308 Hmgn1-rs10 MGI:MGI:96122 +111309 Hmgn1-rs14 MGI:MGI:96126 +111310 Hmgn1-rs15 MGI:MGI:96127 +111311 Hmgn2-rs10 MGI:MGI:96138 +111312 Hmgn2-rs11 MGI:MGI:96139 +111313 Hmgn2-rs12 MGI:MGI:96140 +111314 Hmgn2-rs14 MGI:MGI:96142 +111315 Hmgn2-rs15 MGI:MGI:96143 +111316 Hmgn2-rs17 MGI:MGI:96145 +111317 Hmgn2-rs18 MGI:MGI:96146 +111318 Hmgn2-rs19 MGI:MGI:96147 +111319 Hmgn2-rs20 MGI:MGI:96149 +111320 Hmgn1-rs17 MGI:MGI:99777 +111321 Snrp2b-rs1 MGI:MGI:105962 +111322 Hmgn1-rs12 MGI:MGI:96124 +111323 Hmgn2-rs13 MGI:MGI:96141 +111324 Hmgn2-rs16 MGI:MGI:96144 +111326 Ddx5-ps1 MGI:MGI:105067 +111327 Shc1-rs1 MGI:MGI:2136987 +111328 Atp5b-rs MGI:MGI:107800 +111329 Atp7a-rs1 MGI:MGI:104868 +111331 Atp5k-ps3 MGI:MGI:107266 +111333 Amy MGI:MGI:88018 +111334 Cd1 MGI:MGI:102561 +111335 Cat2 MGI:MGI:88272 +111336 Hoxa MGI:MGI:96169 +111337 Hoxd MGI:MGI:96200 +111338 Ms15-9 MGI:MGI:104569 +111339 Hoxc MGI:MGI:96191 +111340 Ms15-8 MGI:MGI:97156 +111341 Ph MGI:MGI:97571 +111342 Surf MGI:MGI:98442 +111343 Il1 MGI:MGI:96536 +111345 Saa MGI:MGI:98220 +111346 Cm MGI:MGI:88424 +111350 Mmv14 MGI:MGI:97017 +111351 Mmv15 MGI:MGI:97018 +111352 Mmv18 MGI:MGI:97021 +111353 Mmv19 MGI:MGI:97022 +111354 Mmv20 MGI:MGI:97024 +111355 Mmv22 MGI:MGI:97026 +111358 Rsp7 MGI:MGI:98198 +111359 Cryg MGI:MGI:88520 +111360 Mmv16 MGI:MGI:97019 +111361 Mmv17 MGI:MGI:97020 +111363 Spt MGI:MGI:98391 +111364 H2 MGI:MGI:95894 +111367 L1M3 MGI:MGI:103117 +111368 Prn MGI:MGI:97767|Ensembl:ENSMUSG00000098754|Vega:OTTMUSG00000044800 +111369 Mov15 MGI:MGI:97058 +111370 Cyp2d MGI:MGI:88601 +111371 Emv1 MGI:MGI:95325 +111372 Emv2 MGI:MGI:95335 +111373 Emv3 MGI:MGI:95346 +111374 Mtv1 MGI:MGI:97183 +111375 Mtv7 MGI:MGI:97226 +111376 Mtv8 MGI:MGI:97227 +111377 Etn1 MGI:MGI:1316651 +111378 Mtv2 MGI:MGI:97188 +111379 Mtv3 MGI:MGI:97197 +111380 Mtv6 MGI:MGI:97225 +111381 Mtv9 MGI:MGI:97228 +111382 Pad1 MGI:MGI:97470 +111383 Mar1 MGI:MGI:1097713 +111384 Emv11 MGI:MGI:95327 +111385 Mtv33 MGI:MGI:97201 +111386 Rnr4 MGI:MGI:97967 +111387 Mtv56 MGI:MGI:105394 +111388 Emv13 MGI:MGI:95329 +111389 Emv16 MGI:MGI:95332 +111390 Emv17 MGI:MGI:95333 +111391 Emv18 MGI:MGI:95334 +111392 Emv20 MGI:MGI:95336 +111393 Emv21 MGI:MGI:95337 +111394 Emv22 MGI:MGI:95338 +111395 Emv23 MGI:MGI:95339 +111396 Emv24 MGI:MGI:95340 +111397 Emv26 MGI:MGI:95342 +111398 Emv27 MGI:MGI:95343 +111399 Emv29 MGI:MGI:95345 +111400 Emv32 MGI:MGI:95348 +111401 Emv34 MGI:MGI:95350 +111402 Emv37 MGI:MGI:95353 +111403 Emv38 MGI:MGI:95354 +111404 Emv39 MGI:MGI:95355 +111405 Emv42 MGI:MGI:95359 +111406 Emv43 MGI:MGI:95360 +111407 Emv45 MGI:MGI:95362 +111408 Emv46 MGI:MGI:95363 +111409 Emv47 MGI:MGI:95364 +111410 Emv48 MGI:MGI:95365 +111411 Emv52 MGI:MGI:95370 +111412 Emv57 MGI:MGI:95375 +111413 Emv59 MGI:MGI:95377 +111414 Emv60 MGI:MGI:95379 +111415 Mtv13 MGI:MGI:97185 +111416 Mtv14 MGI:MGI:97186 +111417 Mtv17 MGI:MGI:97187 +111418 Mtv23 MGI:MGI:97190 +111419 Mtv27 MGI:MGI:97194 +111420 Mtv29 MGI:MGI:97196 +111421 Mtv30 MGI:MGI:97198 +111422 Mtv32 MGI:MGI:97200 +111423 Mtv34 MGI:MGI:97202 +111424 Mtv35 MGI:MGI:97203 +111425 Mtv39 MGI:MGI:97207 +111426 Mtv40 MGI:MGI:97209 +111427 Mtv41 MGI:MGI:97210 +111428 Mtv44 MGI:MGI:97213 +111429 Mtv52 MGI:MGI:97222 +111430 Mtv54 MGI:MGI:97224 +111431 Emv12 MGI:MGI:95328 +111432 Emv14 MGI:MGI:95330 +111433 Emv25 MGI:MGI:95341 +111434 Emv28 MGI:MGI:95344 +111435 Emv30 MGI:MGI:95347 +111436 Emv33 MGI:MGI:95349 +111437 Emv35 MGI:MGI:95351 +111438 Emv41 MGI:MGI:95358 +111439 Emv44 MGI:MGI:95361 +111440 Emv50 MGI:MGI:95368 +111441 Emv53 MGI:MGI:95371 +111442 Emv54 MGI:MGI:95372 +111443 Emv55 MGI:MGI:95373 +111444 Emv56 MGI:MGI:95374 +111445 Emv58 MGI:MGI:95376 +111446 Emv62 MGI:MGI:95381 +111447 Mtv11 MGI:MGI:97184 +111448 Mtv36 MGI:MGI:97204 +111449 Mtv37 MGI:MGI:97205 +111450 Mtv38 MGI:MGI:97206 +111451 Mtv55 MGI:MGI:103205 +111452 Krt1c MGI:MGI:96697 +111453 Rnr11 MGI:MGI:97961 +111454 Rnr12 MGI:MGI:97962 +111455 Rnr15 MGI:MGI:97964 +111456 Rnr16 MGI:MGI:97965 +111457 Rnr18 MGI:MGI:97966 +111458 Qa2 MGI:MGI:97833 +111459 Rnr13 MGI:MGI:97963 +111460 Gln3-2 MGI:MGI:95732 +111461 Gln3-6 MGI:MGI:95736 +111462 H2-Q MGI:MGI:95927 +111463 H2-T MGI:MGI:95940 +111464 L1Md6-1 MGI:MGI:96722 +111465 L1Md-A1 MGI:MGI:2675503 +111466 Gln3-3 MGI:MGI:95733 +111467 Gln3-5 MGI:MGI:95735 +111468 Gln3-8 MGI:MGI:95738 +111469 Ms6hm3 MGI:MGI:104543 +111470 Xmmv2 MGI:MGI:98996 +111471 Xmmv7 MGI:MGI:99043 +111472 Xmmv8 MGI:MGI:99052 +111473 Xmmv9 MGI:MGI:99053 +111474 Gln3-9 MGI:MGI:102554 +111475 Gln3-4 MGI:MGI:95734 +111476 Gln3-7 MGI:MGI:95737 +111477 Srev5 MGI:MGI:98414 +111478 Loh1 MGI:MGI:99949 +111479 Parb MGI:MGI:1206592 +111480 Xmmv67 MGI:MGI:99040 +111481 Loh2 MGI:MGI:99957 +111482 Grr1 MGI:MGI:95837 +111483 Grr2 MGI:MGI:95838 +111484 Gsta MGI:MGI:95857 +111485 Xmmv22 MGI:MGI:98999 +111486 Xmmv23 MGI:MGI:99000 +111487 Xmmv27 MGI:MGI:99004 +111488 Xmmv29 MGI:MGI:99006 +111489 Xmmv31 MGI:MGI:99008 +111490 Xmmv36 MGI:MGI:99011 +111491 Xmmv42 MGI:MGI:99018 +111492 Xmmv47 MGI:MGI:99023 +111493 Xmmv54 MGI:MGI:99029 +111494 Xmmv58 MGI:MGI:99032 +111495 Xmmv65 MGI:MGI:99038 +111496 Xmmv71 MGI:MGI:99045 +111497 Xmmv73 MGI:MGI:99046 +111498 Xmmv74 MGI:MGI:99047 +111499 Xmmv76 MGI:MGI:99049 +111500 Xmmv79 MGI:MGI:102665 +111501 Rnr19-1 MGI:MGI:104852 +111503 Pmv1 MGI:MGI:97632 +111504 Pmv4 MGI:MGI:97665 +111505 Xmmv50 MGI:MGI:99026 +111506 Xmmv77 MGI:MGI:99050 +111507 Igh MGI:MGI:96442 +111508 Pmv2 MGI:MGI:97643 +111509 Pmv5 MGI:MGI:97676 +111510 Pmv6 MGI:MGI:97687 +111511 Pmv7 MGI:MGI:97698 +111512 Xmmv21 MGI:MGI:98998 +111513 Xmmv75 MGI:MGI:99048 +111514 Xmv6 MGI:MGI:99109 +111515 Pmv3 MGI:MGI:97654 +111516 Pmv8 MGI:MGI:97709 +111517 Pmv9 MGI:MGI:97711 +111518 Cea MGI:MGI:88365 +111519 Igl MGI:MGI:96526 +111520 Pmv18 MGI:MGI:97641 +111521 Pmv29 MGI:MGI:97653 +111522 Pmv40 MGI:MGI:97666 +111523 Pmv45 MGI:MGI:97671 +111524 Tcra-V1 MGI:MGI:98557 +111525 Tcra-V3 MGI:MGI:98567 +111526 Tcra-V4 MGI:MGI:98568 +111527 Tcra-V5 MGI:MGI:98569 +111528 Tcra-V6 MGI:MGI:98570 +111529 Tcra-V7 MGI:MGI:98571 +111530 Tcra-V9 MGI:MGI:98573 +111531 Xmv17 MGI:MGI:99063 +111532 Xmv26 MGI:MGI:99073 +111533 Xmv45 MGI:MGI:99093 +111534 Xmv65 MGI:MGI:99115 +111535 Pmv10 MGI:MGI:97633 +111536 Pmv11 MGI:MGI:97634 +111537 Pmv12 MGI:MGI:97635 +111538 Pmv15 MGI:MGI:97638 +111539 Pmv19 MGI:MGI:97642 +111540 Pmv22 MGI:MGI:97646 +111541 Pmv23 MGI:MGI:97647 +111542 Pmv24 MGI:MGI:97648 +111543 Pmv25 MGI:MGI:97649 +111544 Pmv26 MGI:MGI:97650 +111545 Pmv28 MGI:MGI:97652 +111546 Pmv30 MGI:MGI:97655 +111547 Pmv31 MGI:MGI:97656 +111548 Pmv32 MGI:MGI:97657 +111549 Pmv33 MGI:MGI:97658 +111550 Pmv37 MGI:MGI:97662 +111551 Pmv38 MGI:MGI:97663 +111552 Pmv39 MGI:MGI:97664 +111553 Pmv44 MGI:MGI:97670 +111554 Pmv47 MGI:MGI:97673 +111555 Pmv49 MGI:MGI:97675 +111556 Pmv51 MGI:MGI:97678 +111557 Pmv53 MGI:MGI:97680 +111558 Pmv62 MGI:MGI:97690 +111559 Pmv65 MGI:MGI:97693 +111560 Xmv10 MGI:MGI:99056 +111561 Xmv12 MGI:MGI:99058 +111562 Xmv15 MGI:MGI:99061 +111563 Xmv16 MGI:MGI:99062 +111564 Xmv21 MGI:MGI:99068 +111565 Xmv24 MGI:MGI:99071 +111566 Xmv25 MGI:MGI:99072 +111567 Xmv30 MGI:MGI:99078 +111568 Xmv32 MGI:MGI:99080 +111569 Xmv33 MGI:MGI:99081 +111570 Xmv34 MGI:MGI:99082 +111571 Xmv37 MGI:MGI:99085 +111572 Xmv38 MGI:MGI:99086 +111573 Xmv41 MGI:MGI:99090 +111574 Xmv48 MGI:MGI:99096 +111575 Xmv53 MGI:MGI:99102 +111576 Xmv55 MGI:MGI:99104 +111577 Xmv60 MGI:MGI:99110 +111578 Xmv61 MGI:MGI:99111 +111579 Xmv62 MGI:MGI:99112 +111580 Xmv63 MGI:MGI:99113 +111581 Pmv13 MGI:MGI:97636 +111582 Pmv14 MGI:MGI:97637 +111583 Pmv16 MGI:MGI:97639 +111584 Pmv17 MGI:MGI:97640 +111585 Pmv20 MGI:MGI:97644 +111586 Pmv21 MGI:MGI:97645 +111587 Pmv27 MGI:MGI:97651 +111588 Pmv35 MGI:MGI:97660 +111589 Pmv36 MGI:MGI:97661 +111590 Pmv41 MGI:MGI:97667 +111591 Pmv42 MGI:MGI:97668 +111592 Pmv43 MGI:MGI:97669 +111593 Pmv46 MGI:MGI:97672 +111594 Pmv48 MGI:MGI:97674 +111595 Pmv50 MGI:MGI:97677 +111596 Pmv54 MGI:MGI:97681 +111597 Pmv55 MGI:MGI:97682 +111598 Pmv56 MGI:MGI:97683 +111599 Pmv57 MGI:MGI:97684 +111600 Pmv58 MGI:MGI:97685 +111601 Pmv67 MGI:MGI:97695 +111602 Xmv13 MGI:MGI:99059 +111603 Xmv18 MGI:MGI:99064 +111604 Xmv19 MGI:MGI:99065 +111605 Xmv20 MGI:MGI:99067 +111606 Xmv22 MGI:MGI:99069 +111607 Xmv23 MGI:MGI:99070 +111608 Xmv27 MGI:MGI:99074 +111609 Xmv29 MGI:MGI:99076 +111610 Xmv31 MGI:MGI:99079 +111611 Xmv35 MGI:MGI:99083 +111612 Xmv39 MGI:MGI:99087 +111613 Xmv42 MGI:MGI:99091 +111614 Xmv47 MGI:MGI:99095 +111615 Xmv49 MGI:MGI:99097 +111616 Xmv51 MGI:MGI:99100 +111617 Xmv54 MGI:MGI:99103 +111618 Pmv81 MGI:MGI:107990 +111619 Tcra-V10 MGI:MGI:98558 +111620 Tcra-V11 MGI:MGI:98559 +111621 Tcra-V13 MGI:MGI:98560 +111622 Tcra-V14 MGI:MGI:98561 +111623 Tcra-V15 MGI:MGI:98562 +111624 Xmv36 MGI:MGI:99084 +111625 Xmv50 MGI:MGI:99099 +111626 Xmv57 MGI:MGI:99106 +111627 Tcra-V12 MGI:MGI:99518 +111628 Tcra-V16 MGI:MGI:99519 +111629 Tcra-V17 MGI:MGI:99520 +111630 Tcra-V18 MGI:MGI:99521 +111631 Tcra-V19 MGI:MGI:99522 +111632 Ms7 MGI:MGI:1321083 +111633 Ms3 MGI:MGI:1321087 +111634 Scrd1 MGI:MGI:2148126 +111635 Ms6 MGI:MGI:1321084 +111636 Ms2 MGI:MGI:1321088 +111637 Scrd2 MGI:MGI:2148127 +111638 Ms6-6 MGI:MGI:99625 +111639 Ms6-2 MGI:MGI:97158 +111640 Ms6-4 MGI:MGI:97160 +111641 Ms66 MGI:MGI:1321120 +111642 Ms67 MGI:MGI:1321121 +111643 Ms13 MGI:MGI:1321125 +111644 Ms12 MGI:MGI:1321126 +111645 Ms16 MGI:MGI:1321129 +111646 Ms15 MGI:MGI:1321130 +111647 Ms19 MGI:MGI:1321131 +111648 Ms21 MGI:MGI:1321141 +111649 Igl-1 MGI:MGI:96527 +111650 Igl-2 MGI:MGI:96528 +111651 Ms6-1 MGI:MGI:97157 +111652 Ms6-3 MGI:MGI:97159 +111653 Ms6-5 MGI:MGI:97161 +111654 Ifna MGI:MGI:107670 +111655 Iap17-1 MGI:MGI:109251 +111656 Ms11 MGI:MGI:1321127 +111657 Ms25 MGI:MGI:1321137 +111658 Ms22 MGI:MGI:1321138 +111660 Tcra-V MGI:MGI:98556 +111661 Xlr3 MGI:MGI:98979 +111662 Iap11-1 MGI:MGI:96308 +111663 Iap2-1 MGI:MGI:102662 +111664 Iap11-2 MGI:MGI:96309 +111665 Igh-V12 MGI:MGI:106607 +111666 Igh-V24 MGI:MGI:106917 +111667 Igh-VQ52 MGI:MGI:96488 +111668 Igh-VSM7 MGI:MGI:96491 +111669 Mintc MGI:MGI:96985 +111670 Mintd MGI:MGI:96986 +111671 Myhc MGI:MGI:97254 +111672 Igh-C MGI:MGI:96456 +111673 Igk-V2 MGI:MGI:96505 +111674 Minta MGI:MGI:96983 +111675 Mintb MGI:MGI:96984 +111676 Mpmv3 MGI:MGI:97099 +111677 Ms15-1 MGI:MGI:97149 +111678 Ms15-2 MGI:MGI:97150 +111679 Ms15-5 MGI:MGI:97153 +111680 Ms15-6 MGI:MGI:97154 +111681 Iapt8 MGI:MGI:99788 +111682 Iapt5 MGI:MGI:99790 +111683 Mpmv1 MGI:MGI:97077 +111684 Mpmv5 MGI:MGI:97121 +111685 Mpmv6 MGI:MGI:97132 +111686 Mpmv7 MGI:MGI:97134 +111687 Mpmv9 MGI:MGI:97136 +111688 Ms15-3 MGI:MGI:97151 +111689 Ms15-7 MGI:MGI:97155 +111690 Iapt9 MGI:MGI:99787 +111691 Iapt6 MGI:MGI:99789 +111692 Iapt4 MGI:MGI:99791 +111693 Iapt3 MGI:MGI:99792 +111694 Iapt1 MGI:MGI:99797 +111695 Igh-D MGI:MGI:96457 +111696 Igh-VQ52N MGI:MGI:96489 +111697 Mpmv2 MGI:MGI:97088 +111698 Mpmv4 MGI:MGI:97110 +111699 Mpmv8 MGI:MGI:97135 +111700 Igl-J MGI:MGI:99545 +111702 Mpmv42 MGI:MGI:97113 +111703 Iapt11 MGI:MGI:96384 +111704 Iapt20 MGI:MGI:96387 +111705 Igh-V3609 MGI:MGI:96481 +111706 Mpmv13 MGI:MGI:97081 +111707 Mpmv14 MGI:MGI:97082 +111708 Mpmv16 MGI:MGI:97084 +111709 Mpmv19 MGI:MGI:97087 +111710 Mpmv20 MGI:MGI:97089 +111711 Mpmv21 MGI:MGI:97090 +111712 Mpmv23 MGI:MGI:97092 +111713 Mpmv25 MGI:MGI:97094 +111714 Mpmv27 MGI:MGI:97096 +111715 Mpmv28 MGI:MGI:97097 +111716 Mpmv29 MGI:MGI:97098 +111717 Mpmv32 MGI:MGI:97102 +111718 Mpmv33 MGI:MGI:97103 +111719 Mpmv34 MGI:MGI:97104 +111720 Mpmv35 MGI:MGI:97105 +111721 Mpmv36 MGI:MGI:97106 +111722 Mpmv37 MGI:MGI:97107 +111723 Mpmv41 MGI:MGI:97112 +111724 Mpmv43 MGI:MGI:97114 +111725 Mpmv44 MGI:MGI:97115 +111726 Iapt26 MGI:MGI:99793 +111727 Iapt15 MGI:MGI:99794 +111728 Iapt10 MGI:MGI:99796 +111729 Emv15 MGI:MGI:95331 +111730 Iapt18 MGI:MGI:96385 +111731 Igk-V10 MGI:MGI:96501 +111732 Igk-V11 MGI:MGI:96502 +111733 Igk-V19 MGI:MGI:96504 +111734 Igk-V22 MGI:MGI:96508 +111736 Igk-V31 MGI:MGI:96512 +111737 Mpmv11 MGI:MGI:97079 +111738 Mpmv12 MGI:MGI:97080 +111739 Mpmv15 MGI:MGI:97083 +111740 Mpmv17 MGI:MGI:97085 +111741 Mpmv18 MGI:MGI:97086 +111742 Mpmv22 MGI:MGI:97091 +111743 Mpmv24 MGI:MGI:97093 +111744 Mpmv40 MGI:MGI:97111 +111745 Iapt12 MGI:MGI:99795 +111746 Igk-V14 MGI:MGI:107618 +111747 Iapt19 MGI:MGI:96386 +111748 Tic1 MGI:MGI:104869 +111749 Igh-VGAM3.8 MGI:MGI:96485 +111750 Ms13-19 MGI:MGI:103108 +111751 Ms13-10 MGI:MGI:103110 +111752 Ms13-15 MGI:MGI:103116 +111753 H2-Tlev MGI:MGI:95966 +111754 Iapls2-2 MGI:MGI:96343 +111755 Iapls2-3 MGI:MGI:96345 +111756 Iapls3-4 MGI:MGI:96374 +111757 Iapls1-2 MGI:MGI:96319 +111758 Iapls1-4 MGI:MGI:96327 +111759 Iapls1-7 MGI:MGI:96333 +111760 Iapls1-9 MGI:MGI:96335 +111761 Iapls2-4 MGI:MGI:96348 +111762 Iapls2-5 MGI:MGI:96349 +111763 Iapls2-7 MGI:MGI:96351 +111764 Iapls2-9 MGI:MGI:96353 +111765 Iapls3-1 MGI:MGI:96354 +111766 Iapls3-2 MGI:MGI:96365 +111767 Iapls3-5 MGI:MGI:96377 +111768 Iapls3-9 MGI:MGI:96381 +111769 Iapls1-1 MGI:MGI:96312 +111770 Iapls1-3 MGI:MGI:96325 +111771 Iapls1-5 MGI:MGI:96328 +111772 Iapls1-8 MGI:MGI:96334 +111773 Iapls2-1 MGI:MGI:96336 +111774 Iapls2-6 MGI:MGI:96350 +111775 Iapls3-3 MGI:MGI:96372 +111776 Iapls3-6 MGI:MGI:96378 +111777 Iapls3-7 MGI:MGI:96379 +111778 Iapls3-8 MGI:MGI:96380 +111779 Igk-V15 MGI:MGI:96503 +111780 Igk-V35 MGI:MGI:99453 +111781 Iapls1-11 MGI:MGI:96314 +111782 Iapls1-18 MGI:MGI:96318 +111783 Iapls1-6 MGI:MGI:96332 +111784 Iapls1-14 MGI:MGI:99818 +111785 Hsd3b MGI:MGI:96232 +111786 Iapls1-10 MGI:MGI:96313 +111787 Iapls1-17 MGI:MGI:96317 +111788 Iapls1-29 MGI:MGI:96324 +111789 Iapls2-13 MGI:MGI:96340 +111790 Iapls2-14 MGI:MGI:96341 +111791 Iapls2-34 MGI:MGI:96347 +111792 Iapls3-10 MGI:MGI:96355 +111793 Iapls3-13 MGI:MGI:96358 +111794 Iapls3-16 MGI:MGI:96361 +111795 Iapls3-17 MGI:MGI:96362 +111796 Iapls3-18 MGI:MGI:96363 +111797 Iapls3-19 MGI:MGI:96364 +111798 Iapls3-21 MGI:MGI:96367 +111799 Iapls3-22 MGI:MGI:96368 +111800 Iapls3-26 MGI:MGI:96370 +111801 Iapls3-41 MGI:MGI:99798 +111802 Iapls3-37 MGI:MGI:99800 +111803 Iapls3-35 MGI:MGI:99801 +111804 Iapls3-31 MGI:MGI:99803 +111805 Iapls3-30 MGI:MGI:99804 +111806 Iapls3-29 MGI:MGI:99805 +111807 Iapls2-16 MGI:MGI:99808 +111808 Iapls1-32 MGI:MGI:99809 +111809 Iapls1-31 MGI:MGI:99810 +111810 Iapls1-25 MGI:MGI:99811 +111811 Iapls1-24 MGI:MGI:99812 +111812 Iapls1-20 MGI:MGI:99814 +111813 Iapls1-19 MGI:MGI:99815 +111814 Iapls1-16 MGI:MGI:99816 +111815 Iapls1-15 MGI:MGI:99817 +111816 Iapls2-19 MGI:MGI:102895 +111817 Iapls1-70 MGI:MGI:102899 +111818 Iapls1-65 MGI:MGI:102900 +111819 Iapls1-46 MGI:MGI:102901 +111820 Iapls1-38 MGI:MGI:102902 +111821 Iapls2-25 MGI:MGI:102906 +111822 Iapls2-24 MGI:MGI:102907 +111823 Iapls1-72 MGI:MGI:102908 +111824 Iapls1-66 MGI:MGI:102909 +111825 Iapls1-50 MGI:MGI:102915 +111826 Iapls1-49 MGI:MGI:102916 +111827 Iapls1-47 MGI:MGI:102917 +111828 Iapls1-71 MGI:MGI:102919 +111829 Iapls1-67 MGI:MGI:102920 +111830 Iapls2-28 MGI:MGI:102923 +111831 Iapls2-18 MGI:MGI:102924 +111832 Iapls2-23 MGI:MGI:102938 +111833 Iapls2-38 MGI:MGI:102953 +111834 Iapls1-68 MGI:MGI:102954 +111835 Iapls1-12 MGI:MGI:96315 +111836 Iapls1-13 MGI:MGI:96316 +111837 Iapls1-22 MGI:MGI:96320 +111838 Iapls1-30 MGI:MGI:96326 +111839 Iapls2-10 MGI:MGI:96337 +111840 Iapls2-11 MGI:MGI:96338 +111841 Iapls2-12 MGI:MGI:96339 +111842 Iapls3-11 MGI:MGI:96356 +111843 Iapls3-12 MGI:MGI:96357 +111844 Iapls3-14 MGI:MGI:96359 +111845 Iapls3-15 MGI:MGI:96360 +111846 Iapls3-20 MGI:MGI:96366 +111847 Iapls3-24 MGI:MGI:96369 +111848 Iapls3-38 MGI:MGI:96373 +111849 Iapls3-40 MGI:MGI:96375 +111850 Iapls3-28 MGI:MGI:99806 +111851 Iapls1-21 MGI:MGI:99813 +111852 Iapls2-27 MGI:MGI:102927 +111853 Iapls1-43 MGI:MGI:102937 +111854 Iapls2-21 MGI:MGI:102939 +111855 Iapls2-22 MGI:MGI:102941 +111856 Iapls1-73 MGI:MGI:102951 +111857 Iapls3-65 MGI:MGI:102957 +111858 Iapls1-48 MGI:MGI:1270858 +111859 Iapls2-15 MGI:MGI:96342 +111860 Iapls3-48 MGI:MGI:1270852 +111861 H2-I MGI:MGI:95903 +111862 Iap3ra3 MGI:MGI:99284 +111863 Pltr3 MGI:MGI:97624 +111864 Pltr6 MGI:MGI:97626 +111865 Pltr9 MGI:MGI:97627 +111866 Xltr3 MGI:MGI:98982 +111867 Xltr6 MGI:MGI:98984 +111868 Iap3ra1 MGI:MGI:99273 +111869 Iap3ra5 MGI:MGI:99286 +111870 Iap3ra8 MGI:MGI:99289 +111871 Iap3ra9 MGI:MGI:99290 +111872 Iap3rb1 MGI:MGI:99291 +111873 Iap3rb3 MGI:MGI:99304 +111874 Iap3rb5 MGI:MGI:99306 +111875 Iap3rb8 MGI:MGI:99309 +111876 Iap3rb9 MGI:MGI:99310 +111877 Iap3rc1 MGI:MGI:99311 +111878 Iap3rc2 MGI:MGI:99322 +111879 Iap3rc4 MGI:MGI:99333 +111880 Iap3rc8 MGI:MGI:99337 +111881 Iap3rc9 MGI:MGI:99338 +111882 Iap5ra1 MGI:MGI:99339 +111883 Iap5ra2 MGI:MGI:99344 +111884 Iap5ra4 MGI:MGI:99346 +111885 Iap5ra5 MGI:MGI:99347 +111886 Iap5ra7 MGI:MGI:99349 +111887 Iap5rb1 MGI:MGI:99352 +111888 Iap5rb2 MGI:MGI:99363 +111889 Iap5rb3 MGI:MGI:99369 +111890 Iap5rb6 MGI:MGI:99372 +111891 Iap5rb7 MGI:MGI:99373 +111892 Iap5rb8 MGI:MGI:99374 +111893 Iap5rc2 MGI:MGI:99387 +111894 Iap5rc3 MGI:MGI:99391 +111895 Iap5rc4 MGI:MGI:99392 +111896 Iap5rc5 MGI:MGI:99393 +111897 Xltr9 MGI:MGI:99608 +111898 Xltr8 MGI:MGI:99609 +111899 Pltr1 MGI:MGI:99622 +111900 Pltr4 MGI:MGI:97625 +111901 Xltr1 MGI:MGI:98980 +111902 Xltr2 MGI:MGI:98981 +111903 Xltr5 MGI:MGI:98983 +111904 Iap3rb6 MGI:MGI:99307 +111905 Iap3rc6 MGI:MGI:99335 +111906 Iap5rb4 MGI:MGI:99370 +111907 Iap5rb5 MGI:MGI:99371 +111908 Iap5rc6 MGI:MGI:99394 +111909 Pltr7 MGI:MGI:99615 +111910 Pltr5 MGI:MGI:99616 +111911 Pltr2 MGI:MGI:99617 +111912 Iapls3-54 MGI:MGI:102892 +111913 Iapls3-49 MGI:MGI:102898 +111914 Iapls3-67 MGI:MGI:102903 +111915 Iapls3-66 MGI:MGI:102904 +111916 Iapls3-43 MGI:MGI:102905 +111917 Iapls3-69 MGI:MGI:102911 +111918 Iapls3-52 MGI:MGI:102912 +111919 Iapls3-50 MGI:MGI:102913 +111920 Iapls3-47 MGI:MGI:102914 +111921 Iapls3-44 MGI:MGI:102926 +111922 Iapls3-42 MGI:MGI:96376 +111923 Iap3ra10 MGI:MGI:99274 +111924 Iap3rb10 MGI:MGI:99292 +111925 Iap3rb11 MGI:MGI:99293 +111926 Iap3rb12 MGI:MGI:99294 +111927 Iap3rb13 MGI:MGI:99295 +111928 Iap3rb14 MGI:MGI:99296 +111929 Iap3rb18 MGI:MGI:99300 +111930 Iap3rc10 MGI:MGI:99312 +111931 Iap3rc11 MGI:MGI:99313 +111932 Iap3rc15 MGI:MGI:99317 +111933 Iap3rc27 MGI:MGI:99330 +111934 Iap5ra10 MGI:MGI:99340 +111935 Iap5ra11 MGI:MGI:99341 +111936 Iap5rb11 MGI:MGI:99354 +111937 Iap5rb12 MGI:MGI:99355 +111938 Iap5rb13 MGI:MGI:99356 +111939 Iap5rb14 MGI:MGI:99357 +111940 Iap5rb24 MGI:MGI:99368 +111941 Iap5rc10 MGI:MGI:99377 +111942 Iap5rc12 MGI:MGI:99379 +111943 Iap5rc16 MGI:MGI:99383 +111944 Xltr10 MGI:MGI:99610 +111945 Pltr14 MGI:MGI:99619 +111946 Pltr13 MGI:MGI:99620 +111947 Pltr12 MGI:MGI:99621 +111948 Iapls3-45 MGI:MGI:102936 +111949 Iapls3-53 MGI:MGI:102940 +111950 Iap3ra14 MGI:MGI:99278 +111951 Iap3ra17 MGI:MGI:99281 +111952 Iap3rb17 MGI:MGI:99299 +111953 Iap3rb19 MGI:MGI:99302 +111954 Iap3rc13 MGI:MGI:99315 +111955 Iap3rc17 MGI:MGI:99319 +111956 Iap3rc18 MGI:MGI:99320 +111957 Iap3rc24 MGI:MGI:99327 +111958 Iap5rb10 MGI:MGI:99353 +111959 Iap5rc11 MGI:MGI:99378 +111960 Iap5rc21 MGI:MGI:99389 +111961 Csn MGI:MGI:88539 +111962 Mltr1 MGI:MGI:96996 +111963 Mltr2 MGI:MGI:96997 +111964 Mltr3 MGI:MGI:96998 +111965 Mltr8 MGI:MGI:99627 +111966 Mltr4 MGI:MGI:99629 +111967 Mltr7 MGI:MGI:96999 +111968 Mltr9 MGI:MGI:99626 +111969 Mltr10 MGI:MGI:99630 +111970 Dlx1as MGI:MGI:1195983 +111971 Rnu1b3 MGI:MGI:97975 +111972 Rnu1a2 MGI:MGI:97973 +111973 Rnu3b MGI:MGI:97978 +111974 Mkrn3os MGI:MGI:1338020 +111975 Igf2os MGI:MGI:1195257|Ensembl:ENSMUSG00000086266 +111976 Geot MGI:MGI:1858755 +111977 El1 MGI:MGI:95312 +111978 El2 MGI:MGI:95313 +111979 El4 MGI:MGI:108256 +111980 El3 MGI:MGI:108249 +111981 Eye1 MGI:MGI:1336889 +111982 Obq2 MGI:MGI:109231 +111983 Bdln1 MGI:MGI:109250 +111984 Derm1 MGI:MGI:1890944 +111985 Obq3 MGI:MGI:1100506 +111986 Obq4 MGI:MGI:1100507 +111987 Obq5 MGI:MGI:1349407 +111988 Insq3 MGI:MGI:1932507 +111989 Insq1 MGI:MGI:1889219 +111990 Insq2 MGI:MGI:1932506 +111991 Cq1 MGI:MGI:2137601 +111992 Cq3 MGI:MGI:2137607 +111993 Bfq1 MGI:MGI:1100534 +111994 Emo3 MGI:MGI:1334558 +111995 Insq4 MGI:MGI:1932516 +111996 Insq5 MGI:MGI:1932517 +111997 Cq2 MGI:MGI:2137602 +111998 Hlq4 MGI:MGI:1344357 +111999 Emo2 MGI:MGI:1350919 +112000 Hlq2 MGI:MGI:1344354 +112001 Hlq5 MGI:MGI:1344356 +112002 Hlq3 MGI:MGI:1344425 +112003 Vispl MGI:MGI:1858773 +112004 Fecq1 MGI:MGI:1329006 +112005 Hlq1 MGI:MGI:1344355 +112006 Batq2 MGI:MGI:1344397 +112007 Batq1 MGI:MGI:1344398 +112008 Dob2 MGI:MGI:99950 +112009 Lbw7 MGI:MGI:105971 +112011 Bw6 MGI:MGI:1316640 +112012 Bw8 MGI:MGI:1316643 +112013 Bw5 MGI:MGI:1316682 +112014 Bw7 MGI:MGI:1316684 +112015 Dob3 MGI:MGI:99958 +112016 Dob7 MGI:MGI:1195259 +112017 Bw9 MGI:MGI:1316646 +112018 Bw4 MGI:MGI:1316681 +112019 Dob4 MGI:MGI:107856 +112020 Dob9 MGI:MGI:1201669 +112021 Szv1 MGI:MGI:1098562 +112022 Szv2 MGI:MGI:1098565 +112023 Bw12 MGI:MGI:1316642 +112024 Bw11 MGI:MGI:1316645 +112025 Lwq2 MGI:MGI:1316704 +112026 Lwq1 MGI:MGI:1316739 +112027 Lwq3 MGI:MGI:1316741 +112028 Bw13 MGI:MGI:1889214 +112029 Bw14 MGI:MGI:1889215 +112030 Lwq6 MGI:MGI:1889223 +112031 Lwq7 MGI:MGI:1889224 +112032 Lwq8 MGI:MGI:1889225 +112033 Bw17 MGI:MGI:1932502 +112034 Bw18 MGI:MGI:1932503 +112035 Szv3 MGI:MGI:1098789 +112036 Lwq5 MGI:MGI:1316641 +112037 Bw10 MGI:MGI:1316644 +112038 Lwq4 MGI:MGI:1316744 +112039 Bw15 MGI:MGI:1889216 +112040 Bw16 MGI:MGI:1889217 +112041 Swq3 MGI:MGI:1316679 +112042 Kwq1 MGI:MGI:1316683 +112043 Kwq3 MGI:MGI:1316685 +112044 Kwq2 MGI:MGI:1316686 +112045 Kwq5 MGI:MGI:1316693 +112046 Start1 MGI:MGI:1858758 +112047 Start2 MGI:MGI:1858759 +112048 Kwq6 MGI:MGI:1889220 +112049 Kwq7 MGI:MGI:1889221 +112051 Triglq1 MGI:MGI:1932519 +112052 Mobq1 MGI:MGI:99505 +112053 Mobq2 MGI:MGI:99506 +112054 Mobq4 MGI:MGI:105950 +112055 Kwq4 MGI:MGI:1316680 +112056 Bomb1 MGI:MGI:1332642 +112057 Phrtq1 MGI:MGI:1344386 +112058 Livq1 MGI:MGI:1344422 +112059 Vertcling MGI:MGI:1858756 +112060 Cliff MGI:MGI:1858767 +112061 Swq5 MGI:MGI:1889231 +112062 Melm1 MGI:MGI:1890553 +112063 Nobq2 MGI:MGI:1930243 +112064 Mop1 MGI:MGI:99507 +112065 Mobq3 MGI:MGI:105951 +112066 Swq4 MGI:MGI:1316676 +112067 Livq2 MGI:MGI:1344421 +112068 Melm2 MGI:MGI:1890554 +112069 Melm3 MGI:MGI:1890555 +112070 Bpq1 MGI:MGI:1891313 +112071 Bpq2 MGI:MGI:1891314 +112072 Bpq3 MGI:MGI:1891315 +112073 Bpq4 MGI:MGI:1891316 +112074 Bpq5 MGI:MGI:1891317 +112075 Triglq2 MGI:MGI:1932520 +112076 Phospq1 MGI:MGI:1932521 +112077 Mop3 MGI:MGI:99509 +112078 Oriq2 MGI:MGI:1196238 +112079 Oriq1 MGI:MGI:1196342 +112080 Alcw1 MGI:MGI:1309452 +112081 Alcw2 MGI:MGI:1309537 +112082 Swq1 MGI:MGI:1316677 +112083 Swq2 MGI:MGI:1316695 +112084 Bsc1 MGI:MGI:1891178 +112085 Bpq6 MGI:MGI:1891318 +112086 Oriq5 MGI:MGI:2137610 +112087 Mop2 MGI:MGI:99508 +112088 Alcw3 MGI:MGI:1309538 +112089 Aeyo MGI:MGI:1858757 +112090 Bh4p MGI:MGI:1858764 +112091 Bglq4 MGI:MGI:108557 +112092 Tlq1 MGI:MGI:1277976 +112093 Bglq8 MGI:MGI:108503 +112094 Bglq7 MGI:MGI:108512 +112095 Bglq6 MGI:MGI:108540 +112096 Bglq5 MGI:MGI:108546 +112097 Bglq3 MGI:MGI:108562 +112098 Bglq2 MGI:MGI:108567 +112099 Bglq1 MGI:MGI:108575 +112100 Bmd1 MGI:MGI:1349434 +112101 Etohc1 MGI:MGI:1858387 +112102 Etohc2 MGI:MGI:1858388 +112103 Bglq9 MGI:MGI:108496 +112104 Etohr MGI:MGI:1858902 +112105 Stnn MGI:MGI:2137702 +112106 Bgeq7 MGI:MGI:108516 +112107 Bgeq6 MGI:MGI:108541 +112108 Bgeq5 MGI:MGI:108542 +112109 Bgeq4 MGI:MGI:108547 +112110 Bgeq3 MGI:MGI:108558 +112111 Bgeq2 MGI:MGI:108568 +112112 Bgeq1 MGI:MGI:108576 +112113 Tlf2 MGI:MGI:1330232 +112114 Tbs2 MGI:MGI:1345641 +112115 Bgeq9 MGI:MGI:108504 +112116 Bgeq8 MGI:MGI:108509 +112117 Nnc1 MGI:MGI:1201381 +112118 Tpnr1 MGI:MGI:2137709 +112119 Bglq13 MGI:MGI:108457 +112120 Bglq12 MGI:MGI:108464 +112121 Bglq11 MGI:MGI:108479 +112122 Bglq10 MGI:MGI:108493 +112123 Szs1 MGI:MGI:1098770 +112124 Szs2 MGI:MGI:1098816 +112125 Aliq1 MGI:MGI:1345621 +112126 Szs5 MGI:MGI:1345649 +112127 Bglq14 MGI:MGI:1932348 +112128 Bgeq12 MGI:MGI:108494 +112129 Szs4 MGI:MGI:1098787 +112130 Szs3 MGI:MGI:1098817 +112131 Aaiq1 MGI:MGI:1196361 +112132 Aaiq2 MGI:MGI:1196363 +112133 Aaq1 MGI:MGI:1314875 +112134 Bglq15 MGI:MGI:1932377 +112135 Bglq16 MGI:MGI:1932380 +112136 Bgeq13 MGI:MGI:108480 +112137 Bgeq11 MGI:MGI:108497 +112138 Bgeq10 MGI:MGI:108505 +112139 Bgeq14 MGI:MGI:1932383 +112140 Bgeq15 MGI:MGI:1932385 +112141 Afw4 MGI:MGI:1316667 +112142 Afw1 MGI:MGI:1316672 +112143 Afw2 MGI:MGI:1316673 +112144 Afw3 MGI:MGI:1316674 +112145 Afw9 MGI:MGI:1890482 +112146 Daq1 MGI:MGI:1098256 +112147 Afw8 MGI:MGI:1316663 +112148 Afw5 MGI:MGI:1316668 +112149 Afw6 MGI:MGI:1316669 +112150 Afw7 MGI:MGI:1316670 +112151 Bwem1 MGI:MGI:1858761 +112152 Letohc1 MGI:MGI:1932408 +112153 Skts2 MGI:MGI:104787 +112154 Skts1 MGI:MGI:104788 +112155 Faq9 MGI:MGI:1098209 +112156 Faq1 MGI:MGI:1098216 +112157 Faq2 MGI:MGI:1098217 +112158 Faq3 MGI:MGI:1098218 +112159 Daq3 MGI:MGI:1098255 +112160 Bwem2 MGI:MGI:1858763 +112162 Imh1 MGI:MGI:105967 +112163 Scc2 MGI:MGI:106228 +112164 Faq8 MGI:MGI:1098208 +112165 Faq4 MGI:MGI:1098212 +112166 Faq5 MGI:MGI:1098213 +112167 Faq6 MGI:MGI:1098214 +112168 Faq7 MGI:MGI:1098215 +112169 Daq7 MGI:MGI:1098220 +112170 Daq4 MGI:MGI:1098223 +112171 Daq5 MGI:MGI:1098225 +112172 Daq6 MGI:MGI:1098227 +112173 Daq8 MGI:MGI:1098262 +112174 Daq9 MGI:MGI:1098263 +112175 Skts4 MGI:MGI:1277159 +112176 Afpq3 MGI:MGI:1316709 +112177 Afpq2 MGI:MGI:1316710 +112178 Afpq1 MGI:MGI:1316720 +112179 Wt3q1 MGI:MGI:1344329 +112180 Wt6q1 MGI:MGI:1344348 +112182 Gvhd1 MGI:MGI:1346066 +112183 Skts8 MGI:MGI:1351472 +112184 Skts6 MGI:MGI:1351478 +112185 Skts7 MGI:MGI:1351479 +112186 Gvhd3 MGI:MGI:1858386 +112187 Afpq5 MGI:MGI:1889211 +112188 Afpq9 MGI:MGI:1889213 +112189 Afw11 MGI:MGI:1890484 +112190 Remslp1 MGI:MGI:2137672 +112191 Remslp2 MGI:MGI:2137673 +112192 Remslp4 MGI:MGI:2137675 +112193 Hacu MGI:MGI:103304 +112194 Scc5 MGI:MGI:108458 +112195 Scc4 MGI:MGI:108465 +112196 Scc3 MGI:MGI:108569 +112197 Afpq4 MGI:MGI:1316712 +112198 Wt6q3 MGI:MGI:1344346 +112199 Wt6q2 MGI:MGI:1344411 +112200 Wt3q2 MGI:MGI:1344428 +112201 Skts5 MGI:MGI:1351480 +112202 Skts9 MGI:MGI:1351489 +112203 Afpq6 MGI:MGI:1889212 +112204 Afw10 MGI:MGI:1890483 +112205 Ity2 MGI:MGI:1891849 +112206 Remslp3 MGI:MGI:2137674 +112207 Scc9 MGI:MGI:1347110 +112208 Ity3 MGI:MGI:1891848 +112209 Rapop2 MGI:MGI:104989 +112210 Tlsm1 MGI:MGI:105954 +112211 Daq14 MGI:MGI:1098247 +112212 Daq15 MGI:MGI:1098248 +112213 Daq16 MGI:MGI:1098249 +112214 Daq10 MGI:MGI:1098250 +112215 Daq11 MGI:MGI:1098251 +112216 Daq12 MGI:MGI:1098252 +112217 Daq13 MGI:MGI:1098253 +112218 Faq10 MGI:MGI:1098277 +112219 Faq11 MGI:MGI:1098278 +112220 Wt10q2 MGI:MGI:1344339 +112221 Wt10q1 MGI:MGI:1344340 +112222 Skts12 MGI:MGI:1351470 +112223 Skts11 MGI:MGI:1351483 +112224 Rapop3 MGI:MGI:104994 +112225 Wt10q3 MGI:MGI:1344409 +112226 Skts10 MGI:MGI:1351482 +112227 Afpq10 MGI:MGI:1889210 +112228 Bts2 MGI:MGI:1934674 +112229 Psl1 MGI:MGI:1345637 +112230 Pbw1 MGI:MGI:1345638 +112231 Pid2 MGI:MGI:1890506 +112232 Bts1 MGI:MGI:1890966 +112233 Bhr1 MGI:MGI:104739 +112235 Par3 MGI:MGI:1101767 +112236 Gct2 MGI:MGI:1330296 +112237 Gct3 MGI:MGI:1330297 +112238 Pid3 MGI:MGI:1890507 +112239 Rapop5 MGI:MGI:1890917 +112240 Bhr3 MGI:MGI:104733 +112241 Bhr2 MGI:MGI:104734 +112242 Bhr4 MGI:MGI:108492 +112243 Sluc7 MGI:MGI:1335097 +112244 Aod2 MGI:MGI:1341104 +112246 Sluc9 MGI:MGI:1335080 +112247 Sluc8 MGI:MGI:1335081 +112248 Sluc5 MGI:MGI:1335083 +112249 Sluc6 MGI:MGI:1335085 +112250 Smgd1 MGI:MGI:2136868 +112251 Orch5 MGI:MGI:108002 +112252 Cia2 MGI:MGI:1333775 +112253 Cia3 MGI:MGI:1333814 +112254 Cia4 MGI:MGI:1333858 +112255 Cia7 MGI:MGI:1345670 +112256 Sst1 MGI:MGI:1888685 +112257 Pbwg1 MGI:MGI:3035957 +112258 C10bw2 MGI:MGI:2137239 +112259 C10bw6 MGI:MGI:2137243 +112261 Orch4 MGI:MGI:108003 +112262 Ots1 MGI:MGI:109357 +112263 Orch6 MGI:MGI:1274788 +112264 Tnfp MGI:MGI:1332652 +112265 Cia8 MGI:MGI:1345626 +112266 Dps1 MGI:MGI:2135996 +112267 Dps2 MGI:MGI:2136107 +112268 Dps3 MGI:MGI:2136108 +112269 C10bw3 MGI:MGI:2137240 +112270 C10bw4 MGI:MGI:2137241 +112271 Pbwg6 MGI:MGI:3035963 +112272 Pbwg12 MGI:MGI:3035970 +112273 Orch1 MGI:MGI:97442 +112274 Mvwf MGI:MGI:109512 +112275 Sluc10 MGI:MGI:1335074 +112276 Sluc11 MGI:MGI:1335075 +112277 Bis4 MGI:MGI:1343055 +112278 Pas1 MGI:MGI:97481 +112279 Pas4 MGI:MGI:108510 +112280 Rigs1 MGI:MGI:1330298 +112281 Sluc12 MGI:MGI:1335076 +112282 Sluc13 MGI:MGI:1335077 +112283 Sluc14 MGI:MGI:1335086 +112284 Pas3 MGI:MGI:97483 +112285 Pas7 MGI:MGI:108459 +112287 Exq2 MGI:MGI:1314874 +112288 Pas8 MGI:MGI:1345291 +112289 Exq1 MGI:MGI:1099805 +112290 Lorp1 MGI:MGI:1203483 +112292 Tlsr1 MGI:MGI:106224 +112294 Lmb2 MGI:MGI:1203737 +112295 Lmb1 MGI:MGI:1203738 +112296 Estq4 MGI:MGI:1346081 +112297 Estq3 MGI:MGI:1346096 +112298 Pgct1 MGI:MGI:1888559 +112299 Tlsr2 MGI:MGI:106223 +112300 Lmb4 MGI:MGI:1203735 +112301 Tlsr3 MGI:MGI:1313309 +112302 Etohila MGI:MGI:1858897 +112303 Epd1 MGI:MGI:1274786 +112304 Pas5a MGI:MGI:1345383 +112305 Tlsr6 MGI:MGI:1345406 +112306 Tlsr7 MGI:MGI:1345407 +112307 Mwq1 MGI:MGI:1889226 +112308 Hcs1 MGI:MGI:96056 +112309 Hcs2 MGI:MGI:96057 +112310 Hcs5 MGI:MGI:99635 +112311 Hcs4 MGI:MGI:99636 +112312 Hcs7 MGI:MGI:106010 +112313 Char1 MGI:MGI:1101772 +112314 Char2 MGI:MGI:1101773 +112315 Tria5 MGI:MGI:1343126 +112316 Tria4 MGI:MGI:1343127 +112317 Bwefm MGI:MGI:1858760 +112318 Mwq2 MGI:MGI:1889227 +112319 Mwq3 MGI:MGI:1889228 +112320 Mwq4 MGI:MGI:1889229 +112321 Mwq5 MGI:MGI:1889230 +112322 Tir3a MGI:MGI:1891472 +112323 Tir3b MGI:MGI:1891473 +112324 Tir3c MGI:MGI:1891474 +112325 Wg1 MGI:MGI:1933812 +112326 Wg2 MGI:MGI:1933813 +112327 Wg3 MGI:MGI:1933814 +112328 Hcs6 MGI:MGI:99634 +112329 Tria2 MGI:MGI:1306783 +112330 Tria1 MGI:MGI:1306804 +112331 Wg4 MGI:MGI:1933816 +112332 Athsq1 MGI:MGI:1933987 +112333 Athsq2 MGI:MGI:1933989 +112334 Lore3 MGI:MGI:1096559 +112335 Lore2 MGI:MGI:1096560 +112337 Cara1 MGI:MGI:1933821 +112338 Carfhg1 MGI:MGI:1933824 +112339 Carfhg2 MGI:MGI:1933826 +112340 Lore4 MGI:MGI:1096558 +112341 Lore5 MGI:MGI:1096561 +112342 Cara2 MGI:MGI:1933822 +112343 Cara3 MGI:MGI:1933823 +112344 Feml1 MGI:MGI:1933827 +112345 Feml2 MGI:MGI:1933828 +112346 Mlviq1 MGI:MGI:1306807 +112347 Feml3 MGI:MGI:1933829 +112348 Ednrbm1 MGI:MGI:2137859 +112349 Gasa2 MGI:MGI:1346059 +112350 Gasa1 MGI:MGI:1346075 +112351 Ichs MGI:MGI:1861748 +112352 Nq1 MGI:MGI:2137605 +112353 Mpsq1 MGI:MGI:1203739 +112354 Alcp1 MGI:MGI:107468 +112355 Alcp4 MGI:MGI:1330314 +112356 Cplaq2 MGI:MGI:1277242 +112357 Alcp3 MGI:MGI:1330311 +112358 Nidd5 MGI:MGI:1891280 +112359 Nidd6 MGI:MGI:1891281 +112360 Carp1 MGI:MGI:1933817 +112361 Nidd2 MGI:MGI:1277974 +112362 Nidd4 MGI:MGI:1890953 +112363 Carp2 MGI:MGI:1933818 +112364 Carp3 MGI:MGI:1933819 +112365 Sle3 MGI:MGI:105955 +112366 Sle2 MGI:MGI:105963 +112367 Sle1 MGI:MGI:105969 +112368 Alcp2 MGI:MGI:107452 +112369 Pabr1 MGI:MGI:2137387 +112370 Pabr2 MGI:MGI:2137388 +112371 Fatq1 MGI:MGI:1344342 +112372 Apmt2 MGI:MGI:1891293 +112373 Siafq1 MGI:MGI:1100538 +112374 Apmt1 MGI:MGI:1891292 +112375 Sle1a MGI:MGI:1931842 +112376 Sle1b MGI:MGI:1931843 +112377 Sle1c MGI:MGI:1931844 +112378 Cadfar MGI:MGI:1858180 +112379 Igfbp3q1 MGI:MGI:1890481 +112380 Igfbp3q2 MGI:MGI:1890485 +112381 Eae3 MGI:MGI:105989 +112382 Eae1 MGI:MGI:105991 +112383 Eae2 MGI:MGI:105994 +112384 Eae9 MGI:MGI:1309473 +112385 Eae4 MGI:MGI:1309483 +112386 Eae8 MGI:MGI:1309474 +112387 Eae5 MGI:MGI:1309482 +112388 Eae7 MGI:MGI:1309484 +112389 Eae10 MGI:MGI:1309531 +112390 Eae12 MGI:MGI:1339947 +112391 Eae44a MGI:MGI:1345094 +112392 Eae13 MGI:MGI:1339971 +112393 Eae44b MGI:MGI:1345095 +112394 Eae11 MGI:MGI:1345097 +112395 Mnek1b MGI:MGI:1858511 +112396 Malrd1 - +112397 Tmevd5 MGI:MGI:1891239 +112403 Dxo MGI:MGI:1890444|Ensembl:ENSMUSG00000040482|Vega:OTTMUSG00000037260 +112405 Egln1 MGI:MGI:1932286|Ensembl:ENSMUSG00000031987|Vega:OTTMUSG00000061572 +112406 Egln2 MGI:MGI:1932287|Ensembl:ENSMUSG00000058709|Vega:OTTMUSG00000023172 +112407 Egln3 MGI:MGI:1932288|Ensembl:ENSMUSG00000035105|Vega:OTTMUSG00000034921 +112408 Tas2r116 MGI:MGI:1890258|Ensembl:ENSMUSG00000030194|Vega:OTTMUSG00000056962 +112413 4930447I22Rik MGI:MGI:2148235 +112414 4930540M05Rik MGI:MGI:2148236 +112415 Zfp607b MGI:MGI:2148237|Ensembl:ENSMUSG00000057093|Vega:OTTMUSG00000027197 +112417 Ugt2b37 MGI:MGI:2148239|Ensembl:ENSMUSG00000057425|Vega:OTTMUSG00000026788 +112418 1700102P08Rik MGI:MGI:2148248|Ensembl:ENSMUSG00000032611|Vega:OTTMUSG00000050821 +112419 Ifit1bl2 MGI:MGI:2148249|Ensembl:ENSMUSG00000067297|Vega:OTTMUSG00000016646 +112422 Zfp979 MGI:MGI:2148252|Ensembl:ENSMUSG00000066000|Vega:OTTMUSG00000010656 +112423 Lrnx1 MGI:MGI:2148261 +112424 Lrnx3 MGI:MGI:2148270 +112425 Lrnx5 MGI:MGI:2148304 +112426 Lrnx2 MGI:MGI:2148266 +112427 Lrnx4 MGI:MGI:2148300 +112428 Lrnx6 MGI:MGI:2148305 +112429 Slthsr MGI:MGI:2148365 +112430 Lrncs1 MGI:MGI:2148262 +112431 Lrncs2 MGI:MGI:2148263 +112432 Lrncs3 MGI:MGI:2148264 +112433 Lrnpcs2 MGI:MGI:2148268 +112434 Lrnpcs1 MGI:MGI:2148307 +112435 Lrnpcs3 MGI:MGI:2148302 +113840 Insq6 MGI:MGI:2148493 +113841 Insq7 MGI:MGI:2148494 +113842 Insq8 MGI:MGI:2148495 +113843 Insq9 MGI:MGI:2148496 +113844 Insq10 MGI:MGI:2148497 +113845 Vmn1r48 MGI:MGI:2148508|Ensembl:ENSMUSG00000057592|Vega:OTTMUSG00000037447 +113846 Vmn1r47 MGI:MGI:2148509|Ensembl:ENSMUSG00000060724|Vega:OTTMUSG00000037446 +113847 Vmn1r43 MGI:MGI:2148510|Ensembl:ENSMUSG00000068231|Vega:OTTMUSG00000037440 +113848 Vmn1r42 MGI:MGI:2148511|Ensembl:ENSMUSG00000068232|Vega:OTTMUSG00000037439 +113849 Vmn1r52 MGI:MGI:2148512|Ensembl:ENSMUSG00000060816|Vega:OTTMUSG00000037453 +113850 V1ra8 MGI:MGI:2148513|Ensembl:ENSMUSG00000062546|Vega:OTTMUSG00000037454 +113851 Vmn1r54 MGI:MGI:2148514|Ensembl:ENSMUSG00000047203|Vega:OTTMUSG00000037459 +113852 Vmn1r50 MGI:MGI:2148515|Ensembl:ENSMUSG00000094553|Vega:OTTMUSG00000037489 +113853 Vmn1r53 MGI:MGI:2148516|Ensembl:ENSMUSG00000057697|Vega:OTTMUSG00000037455 +113854 Vmn1r44 MGI:MGI:2148517|Ensembl:ENSMUSG00000068234|Vega:OTTMUSG00000037441 +113855 Vmn1r40 MGI:MGI:2148518|Ensembl:ENSMUSG00000096051|Vega:OTTMUSG00000037435 +113856 Vmn1r46 MGI:MGI:2148519|Ensembl:ENSMUSG00000061653|Vega:OTTMUSG00000037444 +113857 Vmn1r41 MGI:MGI:2148520|Ensembl:ENSMUSG00000094586|Vega:OTTMUSG00000037436 +113858 Vmn1r10 MGI:MGI:2148522|Ensembl:ENSMUSG00000093785|Vega:OTTMUSG00000039886 +113859 Vmn1r29 MGI:MGI:2148523|Ensembl:ENSMUSG00000091734|Vega:OTTMUSG00000039989 +113860 Vmn1r11 MGI:MGI:2148524|Ensembl:ENSMUSG00000093635|Vega:OTTMUSG00000039887 +113861 Vmn1r-ps8 MGI:MGI:2148525 +113862 Vmn1r13 MGI:MGI:2148526|Ensembl:ENSMUSG00000064259|Vega:OTTMUSG00000039910 +113863 Vmn1r15 MGI:MGI:2148527|Ensembl:ENSMUSG00000058731|Vega:OTTMUSG00000039921 +113864 Vmn1r14 MGI:MGI:2148528|Ensembl:ENSMUSG00000093692|Vega:OTTMUSG00000039911 +113865 Vmn1r25 MGI:MGI:2148529|Ensembl:ENSMUSG00000094206|Vega:OTTMUSG00000039949 +113868 Acaa1a MGI:MGI:2148491|Ensembl:ENSMUSG00000036138|Vega:OTTMUSG00000042191 +113869 Vmn1r-ps25 MGI:MGI:2148531 +113870 Vmn1r-ps26 MGI:MGI:2148532 +113871 Vmn1r-ps27 MGI:MGI:2148533 +113872 Vmn1r-ps28 MGI:MGI:2148534 +113873 Vmn1r-ps34 MGI:MGI:2148535 +113874 Vmn1r-ps10 MGI:MGI:2148536 +113875 4931413I07Rik MGI:MGI:2148502 +114051 Lrnx7 MGI:MGI:2148582 +114052 Lrnx8 MGI:MGI:2148583 +114053 Lrnx9 MGI:MGI:2148584 +114054 Lrnx10 MGI:MGI:2148585 +114055 Axtlm MGI:MGI:2148559 +114057 Axtrb1 MGI:MGI:2148562 +114059 Axtrb5 MGI:MGI:2148570 +114060 Axtrb2 MGI:MGI:2148563 +114061 Axtrb3 MGI:MGI:2148564 +114062 Axtrb4 MGI:MGI:2148565 +114063 Axtex MGI:MGI:2148560 +114064 Heal1 MGI:MGI:2148572 +114065 Heal6 MGI:MGI:2148578 +114066 Heal2 MGI:MGI:2148573 +114067 Heal3 MGI:MGI:2148574 +114068 Heal4 MGI:MGI:2148576 +114069 Heal5 MGI:MGI:2148577 +114070 Heal7 MGI:MGI:2148579 +114071 Heal8 MGI:MGI:2148580 +114073 Axtofa2 MGI:MGI:2148545 +114074 Axtofa3 MGI:MGI:2148546 +114075 Axtofa7 MGI:MGI:2148554 +114076 Axtofa1 MGI:MGI:2148544 +114077 Axtofa4 MGI:MGI:2148551 +114078 Axtofa5 MGI:MGI:2148552 +114079 Axtofa6 MGI:MGI:2148553 +114080 Hpic5 MGI:MGI:2148581 +114081 Axtofd1 MGI:MGI:2148555 +114082 Axtofd2 MGI:MGI:2148556 +114083 Axtofd4 MGI:MGI:2148558 +114084 Axtofd3 MGI:MGI:2148557 +114085 Abhr3 MGI:MGI:2148588 +114128 Laptm4b MGI:MGI:1890494|Ensembl:ENSMUSG00000022257 +114141 Cldn16 MGI:MGI:2148742|Ensembl:ENSMUSG00000038148|Vega:OTTMUSG00000028402 +114142 Foxp2 MGI:MGI:2148705|Ensembl:ENSMUSG00000029563|Vega:OTTMUSG00000022513 +114143 Atp6v0b MGI:MGI:1890510|Ensembl:ENSMUSG00000033379|Vega:OTTMUSG00000008663 +114145 Szs7 MGI:MGI:2148669 +114146 Szs8 MGI:MGI:2148670 +114147 Szs9 MGI:MGI:2148671 +114148 Szs11 MGI:MGI:2148673 +114149 Szs10 MGI:MGI:2148672 +114150 Szs12 MGI:MGI:2148674 +114151 Szs13 MGI:MGI:2148675 +114152 Axtav MGI:MGI:2148644 +114153 Taste1 MGI:MGI:2148649 +114154 Taste2 MGI:MGI:2148650 +114155 Taste3 MGI:MGI:2148665 +114156 Taste4 MGI:MGI:2148666 +114157 Taste5 MGI:MGI:2148667 +114158 Cia10 MGI:MGI:2148641 +114159 Taste6 MGI:MGI:2148668 +114161 Cons1 MGI:MGI:2148651 +114162 Cons2 MGI:MGI:2148652 +114163 Cons3 MGI:MGI:2148653 +114164 Cons4 MGI:MGI:2148654 +114165 Cons5 MGI:MGI:2148655 +114166 Cons6 MGI:MGI:2148656 +114167 Etohcta1 MGI:MGI:2148643 +114168 Etohcta2 MGI:MGI:2148648 +114169 Etohcta3 MGI:MGI:2148657 +114170 Etohcta4 MGI:MGI:2148658 +114171 Etohcta5 MGI:MGI:2148659 +114172 Etohcta6 MGI:MGI:2148660 +114173 Etohcta7 MGI:MGI:2148661 +114174 Etohcta8 MGI:MGI:2148662 +114175 Etohcta9 MGI:MGI:2148663 +114176 Etohcta10 MGI:MGI:2148664 +114228 Prss1 MGI:MGI:98839|Ensembl:ENSMUSG00000062751|Vega:OTTMUSG00000026897 +114229 Kiss1r MGI:MGI:2148793|Ensembl:ENSMUSG00000035773 +114230 Aipl1 MGI:MGI:2148800|Ensembl:ENSMUSG00000040554|Vega:OTTMUSG00000006096 +114231 Eae20 MGI:MGI:2148761 +114232 Eae21 MGI:MGI:2148762 +114233 Eae19 MGI:MGI:2148760 +114234 Eae22 MGI:MGI:2148763 +114235 Eae23 MGI:MGI:2148764 +114236 Eae15 MGI:MGI:1891324 +114237 Eae16 MGI:MGI:1891325 +114241 Stk19-ps1 MGI:MGI:2148500 +114249 Npnt MGI:MGI:2148811|Ensembl:ENSMUSG00000040998|Vega:OTTMUSG00000026534 +114250 Many3 MGI:MGI:2148844 +114251 Many1 MGI:MGI:2148845 +114252 Many2 MGI:MGI:2148846 +114253 Many5 MGI:MGI:2148847 +114254 Many4 MGI:MGI:2148848 +114255 Dok4 MGI:MGI:2148865|Ensembl:ENSMUSG00000040631|Vega:OTTMUSG00000061707 +114256 Manz1 MGI:MGI:2148832 +114257 Manz2 MGI:MGI:2148833 +114258 Manz3 MGI:MGI:2148834 +114259 Manz4 MGI:MGI:2148835 +114260 Manz5 MGI:MGI:2148836 +114261 Manz6 MGI:MGI:2148837 +114262 Manz7 MGI:MGI:2148838 +114263 Manz8 MGI:MGI:2148839 +114264 Manz9 MGI:MGI:2148840 +114265 Manh1 MGI:MGI:2148807 +114266 Manh2 MGI:MGI:2148808 +114267 Manh3 MGI:MGI:2148809 +114268 Manh4 MGI:MGI:2148810 +114269 Manh5 MGI:MGI:2148812 +114270 Manh6 MGI:MGI:2148813 +114271 Manh7 MGI:MGI:2148814 +114272 Manh8 MGI:MGI:2148815 +114273 Manh9 MGI:MGI:2148816 +114274 Manz10 MGI:MGI:2148841 +114275 Manz11 MGI:MGI:2148842 +114276 Manz12 MGI:MGI:2148843 +114277 Manh10 MGI:MGI:2148817 +114278 Manh11 MGI:MGI:2148818 +114279 Manh12 MGI:MGI:2148819 +114280 Manh13 MGI:MGI:2148820 +114281 Manh14 MGI:MGI:2148821 +114282 Manh15 MGI:MGI:2148822 +114283 Manh16 MGI:MGI:2148823 +114284 Manh17 MGI:MGI:2148824 +114285 Manh18 MGI:MGI:2148825 +114286 Manh19 MGI:MGI:2148826 +114287 Manh20 MGI:MGI:2148827 +114288 Manh21 MGI:MGI:2148828 +114289 Manh22 MGI:MGI:2148829 +114290 Manh23 MGI:MGI:2148830 +114291 Manh24 MGI:MGI:2148831 +114292 Manh25 MGI:MGI:2148868 +114301 Palmd MGI:MGI:2148896|Ensembl:ENSMUSG00000033377|Vega:OTTMUSG00000029790 +114303 Lcrd MGI:MGI:2148993 +114304 Slc28a3 MGI:MGI:2137361|Ensembl:ENSMUSG00000021553|Vega:OTTMUSG00000032647 +114305 Lrnx11 MGI:MGI:2149001 +114306 Lrnx12 MGI:MGI:2149002 +114307 Lprm1 MGI:MGI:2149003 +114308 Lprm2 MGI:MGI:2149004 +114309 Lprm4 MGI:MGI:2149006 +114310 Lprm3 MGI:MGI:2149005 +114311 Lprm5 MGI:MGI:2149007 +114312 Ccrs1 MGI:MGI:2148995 +114313 Ccrs2 MGI:MGI:2148996 +114314 Im1 MGI:MGI:2148963 +114315 Taste7 MGI:MGI:2148965 +114316 Taste8 MGI:MGI:2148966 +114317 Taste9 MGI:MGI:2148967 +114318 Taste10 MGI:MGI:2148968 +114319 Taste11 MGI:MGI:2148969 +114320 Taste12 MGI:MGI:2148970 +114321 Yaa2 MGI:MGI:2148988 +114322 Yaa3 MGI:MGI:2148990 +114323 Yaa4 MGI:MGI:2148991 +114324 Pas11 MGI:MGI:2148971 +114325 Pas13 MGI:MGI:2148973 +114326 Pas12 MGI:MGI:2148972 +114332 Lyve1 MGI:MGI:2136348|Ensembl:ENSMUSG00000030787|Vega:OTTMUSG00000060185 +114337 Adip1 MGI:MGI:2149041 +114338 Wta1 MGI:MGI:2149058 +114339 Wta2 MGI:MGI:2149060 +114340 Wta3 MGI:MGI:2149061 +114341 Wta4 MGI:MGI:2149062 +114342 Adip2 MGI:MGI:2149042 +114343 Adip3 MGI:MGI:2149043 +114344 Adip4 MGI:MGI:2149044 +114345 Adip5 MGI:MGI:2149045 +114346 Adip7 MGI:MGI:2149048 +114347 Adip6 MGI:MGI:2149047 +114348 Adip8 MGI:MGI:2149049 +114349 Skl1 MGI:MGI:2149050 +114350 Skl2 MGI:MGI:2149051 +114351 Skl3 MGI:MGI:2149052 +114352 Skl4 MGI:MGI:2149053 +114353 Skl5 MGI:MGI:2149054 +114354 Skl6 MGI:MGI:2149055 +114355 Skl7 MGI:MGI:2149057 +114470 Sle7 MGI:MGI:2149093 +114471 Sle8 MGI:MGI:2149095 +114472 Sle9 MGI:MGI:2149094 +114473 Sle10 MGI:MGI:2149096 +114474 Sle11 MGI:MGI:2149097 +114479 Slc5a5 MGI:MGI:2149330|Ensembl:ENSMUSG00000000792|Vega:OTTMUSG00000026286 +114525 Fglu MGI:MGI:2149370 +114526 Bglu1 MGI:MGI:2149372 +114527 Bomd1 MGI:MGI:2149339 +114528 Bomd2 MGI:MGI:2149349 +114529 Bglu2 MGI:MGI:2149373 +114530 Pgia13 MGI:MGI:2149334 +114531 Pgia16 MGI:MGI:2149337 +114532 Pgia14 MGI:MGI:2149335 +114533 Pgia15 MGI:MGI:2149336 +114534 Pgia17 MGI:MGI:2149338 +114535 Bbaa1 MGI:MGI:2149350 +114536 Bbaa2 MGI:MGI:2149351 +114537 Bbaa3 MGI:MGI:2149352 +114538 Bbaa5 MGI:MGI:2149354 +114539 Bbaa9 MGI:MGI:2149358 +114540 Bbaa4 MGI:MGI:2149353 +114541 Bbaa6 MGI:MGI:2149355 +114542 Bbaa7 MGI:MGI:2149356 +114543 Bbaa8 MGI:MGI:2149357 +114544 Dice1 MGI:MGI:2149367 +114545 Dice2 MGI:MGI:2149368 +114564 Csprs MGI:MGI:1891441|Ensembl:ENSMUSG00000062783 +114565 Zbtb21 MGI:MGI:1927240|Ensembl:ENSMUSG00000046962 +114566 Krt82 MGI:MGI:2149248|Ensembl:ENSMUSG00000049548 +114570 Crip3 MGI:MGI:2152434|Ensembl:ENSMUSG00000023968|Vega:OTTMUSG00000036861 +114573 Drld MGI:MGI:1891074 +114574 Hdl1 MGI:MGI:2149551 +114575 Hdl2 MGI:MGI:2149552 +114576 Hdl3 MGI:MGI:2149553 +114577 Hdl4 MGI:MGI:2149554 +114578 Myaa1 MGI:MGI:2149549 +114579 Myaa2 MGI:MGI:2149550 +114580 Yaail MGI:MGI:2149548 +114581 Arvm1 MGI:MGI:2149546 +114582 Arvm2 MGI:MGI:2149547 +114584 Clic1 MGI:MGI:2148924|Ensembl:ENSMUSG00000007041|Vega:OTTMUSG00000037145 +114585 D17H6S53E MGI:MGI:90673|Ensembl:ENSMUSG00000043311|Vega:OTTMUSG00000037181 +114600 Gm4736 MGI:MGI:3647826 +114601 Ehbp1l1 MGI:MGI:3612340|Ensembl:ENSMUSG00000024937 +114602 Zmynd10 MGI:MGI:2387863|Ensembl:ENSMUSG00000010044|Vega:OTTMUSG00000050749 +114604 Prdm15 MGI:MGI:1930121|Ensembl:ENSMUSG00000014039|Vega:OTTMUSG00000028482 +114606 Tle6 MGI:MGI:2149593|Ensembl:ENSMUSG00000034758|Vega:OTTMUSG00000027830 +114607 Smt3h2-ps4 MGI:MGI:2149598 +114608 Cia5 MGI:MGI:1891460 +114615 Elac1 MGI:MGI:1890495|Ensembl:ENSMUSG00000036941|Vega:OTTMUSG00000029778 +114617 Bdln2 MGI:MGI:2149618 +114618 Pheo MGI:MGI:2149623 +114619 Yv MGI:MGI:2149624 +114620 Cdif MGI:MGI:2149622 +114621 Mobq5 MGI:MGI:1890667 +114622 Mobq6 MGI:MGI:1890668 +114623 Mobq7 MGI:MGI:1890669 +114624 Mobq8 MGI:MGI:1890670 +114640 Pth2 MGI:MGI:2152297|Ensembl:ENSMUSG00000038300|Vega:OTTMUSG00000058651 +114641 Rpl31 MGI:MGI:2149632|Ensembl:ENSMUSG00000073702|Vega:OTTMUSG00000050276 +114642 Brdt MGI:MGI:1891374|Ensembl:ENSMUSG00000029279|Vega:OTTMUSG00000017134 +114643 Oas1c MGI:MGI:2149633|Ensembl:ENSMUSG00000001166|Vega:OTTMUSG00000026817 +114644 Slc13a3 MGI:MGI:2149635|Ensembl:ENSMUSG00000018459|Vega:OTTMUSG00000001182 +114645 Abmm MGI:MGI:2149650 +114646 Pkccl MGI:MGI:2149652 +114647 Mmtg1 MGI:MGI:1890550 +114648 Mmtg2 MGI:MGI:1890551 +114649 Mmtg3 MGI:MGI:1890552 +114650 Pkcal MGI:MGI:2149651 +114651 Cia9 MGI:MGI:1890622 +114652 Ly6g5c MGI:MGI:2148974|Ensembl:ENSMUSG00000034482|Vega:OTTMUSG00000037925 +114654 Ly6g6d MGI:MGI:2148931|Ensembl:ENSMUSG00000073413|Vega:OTTMUSG00000037160 +114660 Etos1 MGI:MGI:2149837 +114661 Prss28 MGI:MGI:2149951|Ensembl:ENSMUSG00000024171|Vega:OTTMUSG00000033715 +114662 Prss29 MGI:MGI:2149952|Ensembl:ENSMUSG00000034039 +114663 Impa2 MGI:MGI:2149728|Ensembl:ENSMUSG00000024525 +114664 Hsd17b11 MGI:MGI:2149821|Ensembl:ENSMUSG00000029311|Vega:OTTMUSG00000026783 +114666 Krtap5-5 MGI:MGI:2149673|Ensembl:ENSMUSG00000073785|Vega:OTTMUSG00000060165 +114668 5033404E19Rik MGI:MGI:2149700|Ensembl:ENSMUSG00000102185 +114669 9430032L10Rik MGI:MGI:2149734 +114670 4930573O21Rik MGI:MGI:2149737 +114671 4930444G20Rik MGI:MGI:2149738|Ensembl:ENSMUSG00000069712|Vega:OTTMUSG00000042490 +114672 1700007E05Rik MGI:MGI:2149745 +114673 4930433N12Rik MGI:MGI:2149746|Ensembl:ENSMUSG00000042360 +114674 Gtf2ird2 MGI:MGI:2149780|Ensembl:ENSMUSG00000015942|Vega:OTTMUSG00000024531 +114675 4932431P20Rik MGI:MGI:2149781|Ensembl:ENSMUSG00000074224 +114676 4930519F09Rik MGI:MGI:2149783 +114677 4930590A17Rik MGI:MGI:2149784 +114679 Selenom MGI:MGI:2149786|Ensembl:ENSMUSG00000075702|Vega:OTTMUSG00000005021 +114680 Asthm1 MGI:MGI:2149830 +114681 Asthm2 MGI:MGI:2149831 +114682 Dbsty1 MGI:MGI:2149843 +114683 Dbsty2 MGI:MGI:2149844 +114684 Dbsty3 MGI:MGI:2149845 +114685 Dbsty4 MGI:MGI:2149846 +114686 Im2 MGI:MGI:2149679 +114687 Corn2 MGI:MGI:2149848 +114688 Skull1 MGI:MGI:2149680 +114689 Skull2 MGI:MGI:2149681 +114690 Skull3 MGI:MGI:2149682 +114691 Skull4 MGI:MGI:2149683 +114692 Skull5 MGI:MGI:2149685 +114693 Skull6 MGI:MGI:2149686 +114694 Skull7 MGI:MGI:2149688 +114695 Skull8 MGI:MGI:2149689 +114696 Skull9 MGI:MGI:2149690 +114697 Embl1 MGI:MGI:2149849 +114712 Ferd3l MGI:MGI:2150010|Ensembl:ENSMUSG00000046518 +114713 Rasa2 MGI:MGI:2149960|Ensembl:ENSMUSG00000032413|Vega:OTTMUSG00000020654 +114714 Rad51c MGI:MGI:2150020|Ensembl:ENSMUSG00000007646|Vega:OTTMUSG00000001261 +114715 Spred1 MGI:MGI:2150016|Ensembl:ENSMUSG00000027351|Vega:OTTMUSG00000015239 +114716 Spred2 MGI:MGI:2150019|Ensembl:ENSMUSG00000045671|Vega:OTTMUSG00000005219 +114717 Embl2 MGI:MGI:2149850 +114718 Skull10 MGI:MGI:2149692 +114719 Skull11 MGI:MGI:2149693 +114720 Skull12 MGI:MGI:2149694 +114721 Skull13 MGI:MGI:2149695 +114722 Skull14 MGI:MGI:2149696 +114723 Skull15 MGI:MGI:2149697 +114724 Skull16 MGI:MGI:2149698 +114725 Skull17 MGI:MGI:2149699 +114726 Skull18 MGI:MGI:2149701 +114727 Skull19 MGI:MGI:2149702 +114728 Skull20 MGI:MGI:2149703 +114729 Skull21 MGI:MGI:2149704 +114730 Skull22 MGI:MGI:2149705 +114731 Skull23 MGI:MGI:2149706 +114732 Skull24 MGI:MGI:2149707 +114733 Skull25 MGI:MGI:2149708 +114734 Skull26 MGI:MGI:2149709 +114737 Iba1 MGI:MGI:2149992 +114738 Iba2 MGI:MGI:2149993 +114739 Iba3 MGI:MGI:2149994 +114740 Iba4 MGI:MGI:2149995 +114741 Supt16 MGI:MGI:1890948|Ensembl:ENSMUSG00000035726 +114742 Omlr MGI:MGI:2149847 +114743 Scpro1 MGI:MGI:2149827 +114744 Bwob MGI:MGI:2149826 +114745 Scpro2 MGI:MGI:2149828 +114746 Scpro3 MGI:MGI:2149829 +114747 Daq17 MGI:MGI:2149676 +114748 Daq18 MGI:MGI:2149677 +114749 Daq19 MGI:MGI:2149678 +114750 Pbd1 MGI:MGI:2149727 +114751 Mors2 MGI:MGI:2149823 +114752 Mors1 MGI:MGI:2149822 +114753 Mors3 MGI:MGI:2149824 +114754 Mors4 MGI:MGI:2149825 +114755 Sle12 MGI:MGI:2149721 +114756 Sle13 MGI:MGI:2149722 +114763 G6bos MGI:MGI:2148929 +114774 Pawr MGI:MGI:2149961|Ensembl:ENSMUSG00000035873 +114775 Mym MGI:MGI:1891058 +114776 Actd1 MGI:MGI:2150030 +114777 Actd2 MGI:MGI:2150031 +114778 Actd3 MGI:MGI:2150032 +114779 Actd4 MGI:MGI:2150033 +114806 Tlln MGI:MGI:2150122 +114807 Bwtq3 MGI:MGI:1891195 +114808 Bwtq4 MGI:MGI:2150123 +114809 Bwtq1 MGI:MGI:1891193 +114810 Bwtq2 MGI:MGI:1891194 +114811 Bwtq5 MGI:MGI:2150125 +114812 Bwtq6 MGI:MGI:2150126 +114813 Bw19 MGI:MGI:2150137 +114829 Rencd MGI:MGI:2150194 +114863 Prosc MGI:MGI:1891207|Ensembl:ENSMUSG00000031485|Vega:OTTMUSG00000060984 +114868 Psg25 MGI:MGI:1891357|Ensembl:ENSMUSG00000070798|Vega:OTTMUSG00000043492 +114871 Psg28 MGI:MGI:1891360|Ensembl:ENSMUSG00000030373|Vega:OTTMUSG00000043493 +114872 Psg29 MGI:MGI:1891361|Ensembl:ENSMUSG00000023159|Vega:OTTMUSG00000058192 +114873 Dscaml1 MGI:MGI:2150309|Ensembl:ENSMUSG00000032087|Vega:OTTMUSG00000063511 +114874 Ddhd1 MGI:MGI:2150302|Ensembl:ENSMUSG00000037697|Vega:OTTMUSG00000023929 +114875 Plcz1 MGI:MGI:2150308|Ensembl:ENSMUSG00000030230|Vega:OTTMUSG00000023670 +114886 Cygb MGI:MGI:2149481|Ensembl:ENSMUSG00000020810|Vega:OTTMUSG00000003946 +114888 Rmcs5 MGI:MGI:1890700 +114889 Vsx1 MGI:MGI:1890816|Ensembl:ENSMUSG00000033080|Vega:OTTMUSG00000015757 +114893 Dcun1d1 MGI:MGI:2150386|Ensembl:ENSMUSG00000027708|Vega:OTTMUSG00000028173 +114896 Afg3l1 MGI:MGI:1928277|Ensembl:ENSMUSG00000031967|Vega:OTTMUSG00000031059 +114910 Cosz1 MGI:MGI:2150404 +114911 Cosz2 MGI:MGI:2150405 +114912 Cosz3 MGI:MGI:2150406 +114913 Alcp25 MGI:MGI:2150421 +116450 Etia MGI:MGI:2150636 +116451 Bhr6 MGI:MGI:2150651 +116452 Asm2 MGI:MGI:2150643 +116453 Lore8 MGI:MGI:2150637 +116454 Asm1 MGI:MGI:2150642 +116513 Pvcan1 MGI:MGI:2150657 +116514 Pvcan2 MGI:MGI:2150658 +116515 Pvcan3 MGI:MGI:2150659 +116516 Eae24 MGI:MGI:2150664 +116520 Obq7 MGI:MGI:2150696 +116521 Obq8 MGI:MGI:2150697 +116522 Obq9 MGI:MGI:2150698 +116523 Obq10 MGI:MGI:2150699 +116524 Obq11 MGI:MGI:2150700 +116525 Obq12 MGI:MGI:2150701 +116526 Obq13 MGI:MGI:2150702 +116527 Obq14 MGI:MGI:2150703 +116528 Obq15 MGI:MGI:2150704 +116529 Hts MGI:MGI:2150693 +116530 Tbrs1 MGI:MGI:2150671 +116531 Tbrs2 MGI:MGI:2150672 +116532 Tbrs3 MGI:MGI:2150673 +116536 Alan2 MGI:MGI:2150757 +116537 Modm MGI:MGI:2150760 +116538 Aaq2 MGI:MGI:2150745 +116602 D7Tem2 MGI:MGI:2150886 +116603 D7Tem3 MGI:MGI:2150887 +116604 D7Tem1 MGI:MGI:2150888 +116605 D7Tem8 MGI:MGI:2150889 +116606 D7Tem4 MGI:MGI:2150890 +116607 D7Tem9 MGI:MGI:2150891 +116608 D7Tem10 MGI:MGI:2150892 +116609 D7Tem11 MGI:MGI:2150893 +116610 D7Tem12 MGI:MGI:2150896 +116611 D7Tem13 MGI:MGI:2150898 +116612 D7Tem14 MGI:MGI:2150899 +116613 D7Tem15 MGI:MGI:2150900 +116614 D7Tem16 MGI:MGI:2150901 +116615 D7Tem17 MGI:MGI:2150902 +116616 D7Tem18 MGI:MGI:2150903 +116617 D7Tem21 MGI:MGI:2150904 +116618 D7Tem22 MGI:MGI:2150905 +116619 D7Tem23 MGI:MGI:2150906 +116620 Bits1 MGI:MGI:2150763 +116621 Bits2 MGI:MGI:2150764 +116622 Bits3 MGI:MGI:2150765 +116623 Bits4 MGI:MGI:2150766 +116626 Cafq1 MGI:MGI:2150827 +116627 Cafq2 MGI:MGI:2150828 +116628 Cafq3 MGI:MGI:2150829 +116701 Fgfrl1 MGI:MGI:2150920|Ensembl:ENSMUSG00000008090|Vega:OTTMUSG00000054022 +116702 Listr1 MGI:MGI:2150908 +116703 Listr2 MGI:MGI:2150909 +116704 Lfp1 MGI:MGI:2150921 +116705 Lfp2 MGI:MGI:2150922 +116706 Lfp3 MGI:MGI:2150923 +116707 Uvbi1 MGI:MGI:2150915 +116708 Uvbi2 MGI:MGI:2150916 +116716 Ihtw1 MGI:MGI:1890561 +116731 Pcdha1 MGI:MGI:2150982|Ensembl:ENSMUSG00000103442|Vega:OTTMUSG00000050581 +116732 Tsga13 MGI:MGI:1891413|Ensembl:ENSMUSG00000039032|Vega:OTTMUSG00000055935 +116733 Vps4a MGI:MGI:1890520|Ensembl:ENSMUSG00000031913|Vega:OTTMUSG00000031758 +116734 Cocrb1 MGI:MGI:2150984 +116735 Cocrb2 MGI:MGI:2150985 +116736 Cocrb3 MGI:MGI:2150987 +116737 Cocrb4 MGI:MGI:2150989 +116738 Tlsr8 MGI:MGI:2150967 +116739 Dautb1 MGI:MGI:2150986 +116746 Defb6 MGI:MGI:2151044|Ensembl:ENSMUSG00000050756|Vega:OTTMUSG00000020598 +116747 Rmcs2 MGI:MGI:1890697 +116748 Lsm10 MGI:MGI:2151045|Ensembl:ENSMUSG00000050188|Vega:OTTMUSG00000009295 +116749 Drb1 MGI:MGI:2150993 +116750 Cocrb5 MGI:MGI:2150991 +116751 Cocrb6 MGI:MGI:2150992 +116752 Drb2 MGI:MGI:2150994 +116753 Cocrb7 MGI:MGI:2150995 +116754 Cocrb8 MGI:MGI:2150997 +116755 Cocrb9 MGI:MGI:2150998 +116756 Drb3 MGI:MGI:2151000 +116757 Drb4 MGI:MGI:2151006 +116758 Drb5 MGI:MGI:2151007 +116759 Drb6 MGI:MGI:2151008 +116760 Drb7 MGI:MGI:2151009 +116761 Drb8 MGI:MGI:2151012 +116762 Drb9 MGI:MGI:2151018 +116763 Cocrb10 MGI:MGI:2150999 +116764 Cocrb13 MGI:MGI:2151005 +116765 Cocrb11 MGI:MGI:2151001 +116766 Cocrb12 MGI:MGI:2151002 +116767 Cocrb14 MGI:MGI:2151010 +116768 Cocrb15 MGI:MGI:2151011 +116769 Cocrb16 MGI:MGI:2151014 +116770 Cocia3 MGI:MGI:2151049 +116771 Cocia1 MGI:MGI:2151047 +116772 Cocia2 MGI:MGI:2151048 +116773 Dautb2 MGI:MGI:2150996 +116774 Dautb3 MGI:MGI:2151003 +116775 Dautb4 MGI:MGI:2151004 +116810 Foxn4 MGI:MGI:2151057|Ensembl:ENSMUSG00000042002|Vega:OTTMUSG00000014418 +116811 Zim3 MGI:MGI:2151058|Ensembl:ENSMUSG00000108043 +116813 Angle5 MGI:MGI:2151080 +116814 Actvty2 MGI:MGI:2151089 +116815 Actvty1 MGI:MGI:2151087 +116816 Frp1 MGI:MGI:2151076 +116817 Frp2 MGI:MGI:2151078 +116818 Frp3 MGI:MGI:2151084 +116819 Angle4 MGI:MGI:2151079 +116820 Angle1 MGI:MGI:2151082 +116821 Angle2 MGI:MGI:2151083 +116822 Angle3 MGI:MGI:2151088 +116823 Disso1 MGI:MGI:2151085 +116824 Disso2 MGI:MGI:2151086 +116825 Amp2 MGI:MGI:2151073 +116826 Amp1 MGI:MGI:2151074 +116827 Idd20 MGI:MGI:2151061 +116837 Rims1 MGI:MGI:2152971|Ensembl:ENSMUSG00000041670 +116838 Rims2 MGI:MGI:2152972|Ensembl:ENSMUSG00000037386 +116847 Prelp MGI:MGI:2151110|Ensembl:ENSMUSG00000041577|Vega:OTTMUSG00000026872 +116848 Baz2a MGI:MGI:2151152|Ensembl:ENSMUSG00000040054 +116849 Iltifb MGI:MGI:2151139|Ensembl:ENSMUSG00000090461|Vega:OTTMUSG00000042451 +116850 A430106F20Rik MGI:MGI:2151102 +116852 Akr1c20 MGI:MGI:2151104|Ensembl:ENSMUSG00000054757|Vega:OTTMUSG00000027695 +116853 Prdt4 MGI:MGI:2151147 +116854 Rhs1 MGI:MGI:2151137 +116855 Bdt1 MGI:MGI:2151119 +116856 Bdt2 MGI:MGI:2151120 +116857 Bdt3 MGI:MGI:2151121 +116858 Bdt4 MGI:MGI:2151122 +116859 Bdt5 MGI:MGI:2151123 +116860 Bdt6 MGI:MGI:2151124 +116861 Prdt1 MGI:MGI:2151144 +116862 Prdt2 MGI:MGI:2151145 +116863 Prdt3 MGI:MGI:2151146 +116870 Mta1 MGI:MGI:2150037|Ensembl:ENSMUSG00000021144|Vega:OTTMUSG00000017198 +116871 Mta3 MGI:MGI:2151172|Ensembl:ENSMUSG00000055817|Vega:OTTMUSG00000017301 +116872 Serpinb7 MGI:MGI:2151053|Ensembl:ENSMUSG00000067001|Vega:OTTMUSG00000021004 +116873 Stim2 MGI:MGI:2151156|Ensembl:ENSMUSG00000039156|Vega:OTTMUSG00000026433 +116874 Hipp1 MGI:MGI:2151183 +116875 Hipp2 MGI:MGI:2151184 +116876 Pgia1 MGI:MGI:2151209 +116877 Pgia2 MGI:MGI:2151210 +116878 Pgia3 MGI:MGI:2151211 +116879 Pgia4 MGI:MGI:2151212 +116880 Pgia5 MGI:MGI:2151213 +116881 Pgia6 MGI:MGI:2151214 +116882 Pgia7 MGI:MGI:2151215 +116883 Pgia8 MGI:MGI:2151216 +116884 Pgia9 MGI:MGI:2151217 +116885 Pgia10 MGI:MGI:2151218 +116886 Pgia11 MGI:MGI:2151219 +116887 Pgia12 MGI:MGI:2151220 +116888 Eae14 MGI:MGI:1891336 +116889 Eae17 MGI:MGI:1891326 +116890 Eae25 MGI:MGI:2151194 +116891 Derl2 MGI:MGI:2151483|Ensembl:ENSMUSG00000018442|Vega:OTTMUSG00000006077 +116902 Lvif MGI:MGI:2151332 +116903 Calcb MGI:MGI:2151254|Ensembl:ENSMUSG00000030666|Vega:OTTMUSG00000044347 +116904 Alpk3 MGI:MGI:2151224|Ensembl:ENSMUSG00000038763|Vega:OTTMUSG00000017161 +116905 Dph1 MGI:MGI:2151233|Ensembl:ENSMUSG00000078789|Vega:OTTMUSG00000006194 +116906 Char4 MGI:MGI:2151486 +116907 Ritls MGI:MGI:2151357 +116909 Cts7-ps MGI:MGI:2151716 +116911 Cts8-ps MGI:MGI:2151708 +116912 Sox16 MGI:MGI:1890761 +116913 Tpbpb MGI:MGI:2151721|Ensembl:ENSMUSG00000062705 +116914 Slc19a2 MGI:MGI:1928761|Ensembl:ENSMUSG00000040918|Vega:OTTMUSG00000031583 +116915 D13Jde2 MGI:MGI:2151597 +116916 D13Jde3 MGI:MGI:2151598 +116917 D13Jde4 MGI:MGI:2151600 +116918 D13Jde5 MGI:MGI:2151609 +116919 D13Jde6 MGI:MGI:2151610 +116920 D13Jde7 MGI:MGI:2151611 +116921 D13Jde8 MGI:MGI:2151612 +116922 D13Jde9 MGI:MGI:2151613 +116923 D13Jde10 MGI:MGI:2151614 +116924 D13Jde11 MGI:MGI:2151615 +116925 D13Jde12 MGI:MGI:2151616 +116926 D13Jde13 MGI:MGI:2151617 +116927 Artles MGI:MGI:2151624 +116929 Stia1 MGI:MGI:2151739 +116930 Stia2 MGI:MGI:2151740 +116939 Pnpla3 MGI:MGI:2151796|Ensembl:ENSMUSG00000041653 +116940 Tgs1 MGI:MGI:2151797|Ensembl:ENSMUSG00000028233|Vega:OTTMUSG00000004256 +116943 Naad1 MGI:MGI:2151783 +116944 Naad2 MGI:MGI:2151784 +116945 Naad3 MGI:MGI:2151785 +116946 Naad4 MGI:MGI:2151786 +116947 Naad5 MGI:MGI:2151787 +116948 Naad8 MGI:MGI:2151790 +116949 Naad9 MGI:MGI:2151791 +116950 Naad6 MGI:MGI:2151788 +116951 Naad7 MGI:MGI:2151789 +116952 Bulb1 MGI:MGI:2151806 +116953 Bulb2 MGI:MGI:2151807 +116954 Bulb4 MGI:MGI:2151809 +116955 Bulb3 MGI:MGI:2151808 +116956 Trbv4c2 MGI:MGI:1927661 +116957 Trbv4c1 MGI:MGI:1927660 +116972 Fam57a MGI:MGI:2151840|Ensembl:ENSMUSG00000069808|Vega:OTTMUSG00000006227 +116974 Nsv1 MGI:MGI:2151875 +116975 Elmaz1 MGI:MGI:2151843 +116976 Elmaz2 MGI:MGI:2151844 +116977 Morph1 MGI:MGI:2151858 +116978 Morph2 MGI:MGI:2151859 +116979 Morph3 MGI:MGI:2151860 +116980 Morph4 MGI:MGI:2151861 +116981 Pbw3 MGI:MGI:2151853 +116982 Pbwm MGI:MGI:2151854 +117004 Olfr73 MGI:MGI:2151908|Ensembl:ENSMUSG00000075140|Vega:OTTMUSG00000013902 +117005 Olfr74 MGI:MGI:2151909|Ensembl:ENSMUSG00000075142|Vega:OTTMUSG00000013890 +117006 Pitm1 MGI:MGI:2151895 +117007 Pitm2 MGI:MGI:2151896 +117008 Pitm3 MGI:MGI:2151897 +117009 Pitm4 MGI:MGI:2151898 +117010 Datd MGI:MGI:2151915 +117011 Tabw MGI:MGI:1932202 +117012 Cgnz1 MGI:MGI:2151890 +117013 Adaz1 MGI:MGI:2151891 +117014 Tafat MGI:MGI:1932203 +117066 Cts3 MGI:MGI:2151929|Ensembl:ENSMUSG00000074870 +117067 D16H21S337E MGI:MGI:2136888 +117068 D11Lgp3e MGI:MGI:1931561 +117069 D11Lgp4e MGI:MGI:1931563 +117070 D18Tlj1e MGI:MGI:1927066 +117071 T2dm3 MGI:MGI:2152041 +117072 T2dm2 MGI:MGI:2152039 +117074 Actre1 MGI:MGI:2151936 +117075 Actre2 MGI:MGI:2151937 +117076 Actre3 MGI:MGI:2151938 +117077 Actre4 MGI:MGI:2151939 +117078 Cpfd2 MGI:MGI:2151920 +117079 Cpfd3 MGI:MGI:2151922 +117080 Cpfd4 MGI:MGI:2151923 +117081 Cpfd1 MGI:MGI:2151919 +117082 Cpfd5 MGI:MGI:2151924 +117083 Tne1 MGI:MGI:2151921 +117109 Pop5 MGI:MGI:2151221|Ensembl:ENSMUSG00000060152|Vega:OTTMUSG00000014635 +117110 D12Pgn1 MGI:MGI:1891448 +117111 D12Pgn6 MGI:MGI:1891453 +117112 D12Pgn2 MGI:MGI:1891449 +117113 D12Pgn3 MGI:MGI:1891450 +117114 D12Pgn4 MGI:MGI:1891451 +117115 D12Pgn5 MGI:MGI:1891452 +117116 D12Pgn7 MGI:MGI:1891454 +117146 Ube3b MGI:MGI:1891295|Ensembl:ENSMUSG00000029577|Vega:OTTMUSG00000014459 +117147 Acsm1 MGI:MGI:2152200|Ensembl:ENSMUSG00000033533|Vega:OTTMUSG00000023676 +117148 Necab2 MGI:MGI:2152211|Ensembl:ENSMUSG00000031837|Vega:OTTMUSG00000023425 +117149 Tirap MGI:MGI:2152213|Ensembl:ENSMUSG00000032041|Vega:OTTMUSG00000042147 +117150 Pip4k2c MGI:MGI:2152214|Ensembl:ENSMUSG00000025417 +117158 Scgb3a2 MGI:MGI:2153470|Ensembl:ENSMUSG00000038791|Vega:OTTMUSG00000049045 +117160 Ttyh2 MGI:MGI:2157091|Ensembl:ENSMUSG00000034714|Vega:OTTMUSG00000003427 +117161 BB230421 MGI:MGI:2152273 +117162 AA060545 MGI:MGI:2152271 +117167 Steap4 MGI:MGI:1923560|Ensembl:ENSMUSG00000012428|Vega:OTTMUSG00000054267 +117170 4930598A11Rik MGI:MGI:2152336 +117171 1110038F14Rik MGI:MGI:2152337|Ensembl:ENSMUSG00000063236 +117172 2310034C09Rik MGI:MGI:2152338|Ensembl:ENSMUSG00000068078|Vega:OTTMUSG00000046075 +117174 4921509O09Rik MGI:MGI:2152341 +117197 Bloc1s4 MGI:MGI:1929230|Ensembl:ENSMUSG00000060708|Vega:OTTMUSG00000056095 +117198 Ivns1abp MGI:MGI:2152389|Ensembl:ENSMUSG00000023150|Vega:OTTMUSG00000049560 +117202 l9Rl1 MGI:MGI:1889312 +117203 l9Rl2 MGI:MGI:1889313 +117204 l9Rl3 MGI:MGI:1889314 +117205 l9Rl4 MGI:MGI:1889315 +117206 l9Rl5 MGI:MGI:1889316 +117207 l9Rl6 MGI:MGI:1889317 +117208 l9Rl7 MGI:MGI:1889318 +117209 l9Rl8 MGI:MGI:1889319 +117211 kkt MGI:MGI:1354693 +117212 pdpv MGI:MGI:2137370 +117214 mrct MGI:MGI:1890503 +117216 Thim MGI:MGI:1355309 +117217 Ap1q MGI:MGI:2152428 +117218 Ap2q MGI:MGI:2152429 +117219 Ap3q MGI:MGI:2152430 +117220 Ap5q MGI:MGI:2152432 +117221 Ap6q MGI:MGI:2152433 +117222 Ap4q MGI:MGI:2152431 +117223 pogo MGI:MGI:1932969 +117225 wam MGI:MGI:1354982 +117226 nma MGI:MGI:1855684 +117228 nelg MGI:MGI:1890459 +117229 Stk33 MGI:MGI:2152419|Ensembl:ENSMUSG00000031027|Vega:OTTMUSG00000020064 +117244 Exen1 MGI:MGI:1933785 +117290 Lxl MGI:MGI:2152569 +117291 Dyscalc2 MGI:MGI:2152560 +117292 Dyscalc3 MGI:MGI:2152561 +117293 Dyscalc4 MGI:MGI:2152562 +117562 Lch MGI:MGI:2152768 +117563 Bswt MGI:MGI:2152776 +117566 MHAa97h7 MGI:MGI:2152791 +117567 40.MMHAP76FLF4 MGI:MGI:2152795 +117568 30.MMHAP16FRB12 MGI:MGI:2152793 +117569 DXMgc92 MGI:MGI:1859296 +117570 DXMgc93 MGI:MGI:1859297 +117571 DXMgc94 MGI:MGI:1859298 +117572 DXMgc95 MGI:MGI:1859299 +117573 DXJti3 MGI:MGI:1206588 +117574 DXJti2 MGI:MGI:1206589 +117575 DXMgc6 MGI:MGI:1099457 +117576 DXMgc83 MGI:MGI:1350963 +117577 DXMgc47 MGI:MGI:1350979 +117578 Char3 MGI:MGI:2152772 +117586 A1bg MGI:MGI:2152878|Ensembl:ENSMUSG00000022347 +117587 Apoca MGI:MGI:2152879 +117589 Asb7 MGI:MGI:2152835|Ensembl:ENSMUSG00000030509|Vega:OTTMUSG00000028988 +117590 Asb10 MGI:MGI:2152836|Ensembl:ENSMUSG00000038204|Vega:OTTMUSG00000026697 +117591 Slc2a9 MGI:MGI:2152844|Ensembl:ENSMUSG00000005107|Vega:OTTMUSG00000026252 +117592 B3galt6 MGI:MGI:2152819|Ensembl:ENSMUSG00000050796|Vega:OTTMUSG00000010988 +117599 Helb MGI:MGI:2152895|Ensembl:ENSMUSG00000020228|Vega:OTTMUSG00000033558 +117600 Srgap1 MGI:MGI:2152936|Ensembl:ENSMUSG00000020121|Vega:OTTMUSG00000032486 +117606 Boc MGI:MGI:2151153|Ensembl:ENSMUSG00000022687|Vega:OTTMUSG00000014980 +118435 Ms10v MGI:MGI:2153033 +118445 Klf16 MGI:MGI:2153049|Ensembl:ENSMUSG00000035397|Vega:OTTMUSG00000040152 +118446 Gjc3 MGI:MGI:2153041|Ensembl:ENSMUSG00000056966|Vega:OTTMUSG00000054655 +118449 Synpo2 MGI:MGI:2153070|Ensembl:ENSMUSG00000050315|Vega:OTTMUSG00000021275 +118451 Mrps2 MGI:MGI:2153089|Ensembl:ENSMUSG00000035772|Vega:OTTMUSG00000011644 +118452 Baalc MGI:MGI:1928704 +118453 Mmp28 MGI:MGI:2153062|Ensembl:ENSMUSG00000020682|Vega:OTTMUSG00000000928 +118454 Gjc2 MGI:MGI:2153060|Ensembl:ENSMUSG00000043448|Vega:OTTMUSG00000005785 +121021 Cspg4 MGI:MGI:2153093|Ensembl:ENSMUSG00000032911|Vega:OTTMUSG00000063132 +121022 Mrps6 MGI:MGI:2153111|Ensembl:ENSMUSG00000039680|Vega:OTTMUSG00000025871 +140474 Muc4 MGI:MGI:2153525|Ensembl:ENSMUSG00000079620 +140475 Bsnd MGI:MGI:2153465|Ensembl:ENSMUSG00000025418|Vega:OTTMUSG00000008195 +140476 Strc MGI:MGI:2153816|Ensembl:ENSMUSG00000033498|Vega:OTTMUSG00000015264 +140477 Dmbx1 MGI:MGI:2153518|Ensembl:ENSMUSG00000028707|Vega:OTTMUSG00000008711 +140481 Man2a2 MGI:MGI:2150656|Ensembl:ENSMUSG00000038886|Vega:OTTMUSG00000058665 +140482 Zfp358 MGI:MGI:2153740|Ensembl:ENSMUSG00000047264|Vega:OTTMUSG00000059165 +140483 Hnmt MGI:MGI:2153181|Ensembl:ENSMUSG00000026986|Vega:OTTMUSG00000011800 +140484 Pofut1 MGI:MGI:2153207|Ensembl:ENSMUSG00000046020|Vega:OTTMUSG00000016735 +140486 Igf2bp1 MGI:MGI:1890357|Ensembl:ENSMUSG00000013415|Vega:OTTMUSG00000001937 +140488 Igf2bp3 MGI:MGI:1890359|Ensembl:ENSMUSG00000029814|Vega:OTTMUSG00000057404 +140489 Bhlhe23 MGI:MGI:2153710|Ensembl:ENSMUSG00000045493|Vega:OTTMUSG00000016272 +140491 Ppp1r3a MGI:MGI:2153588|Ensembl:ENSMUSG00000042717|Vega:OTTMUSG00000057098 +140492 Kcnn2 MGI:MGI:2153182|Ensembl:ENSMUSG00000054477|Vega:OTTMUSG00000044935 +140493 Kcnn3 MGI:MGI:2153183|Ensembl:ENSMUSG00000000794|Vega:OTTMUSG00000027213 +140494 Atp6v0a4 MGI:MGI:2153480|Ensembl:ENSMUSG00000038600|Vega:OTTMUSG00000022440 +140495 Mopkd1 MGI:MGI:2153658 +140496 Mopkd2 MGI:MGI:2153659 +140497 Cd300c2 MGI:MGI:2153249|Ensembl:ENSMUSG00000044811|Vega:OTTMUSG00000003604 +140498 Rxfp2 MGI:MGI:2153463|Ensembl:ENSMUSG00000053368|Vega:OTTMUSG00000021307 +140499 Ube2j2 MGI:MGI:2153608|Ensembl:ENSMUSG00000023286|Vega:OTTMUSG00000010983 +140500 Acap3 MGI:MGI:2153589|Ensembl:ENSMUSG00000029033|Vega:OTTMUSG00000010848 +140501 Gm20552 MGI:MGI:5295659 +140546 Eri3 MGI:MGI:2153887|Ensembl:ENSMUSG00000033423|Vega:OTTMUSG00000008661 +140551 Atp5l-ps1 MGI:MGI:2153586 +140554 Usf2-ps1 MGI:MGI:2153531 +140557 Smc1b MGI:MGI:2154049|Ensembl:ENSMUSG00000022432 +140559 Igsf8 MGI:MGI:2154090|Ensembl:ENSMUSG00000038034|Vega:OTTMUSG00000021443 +140570 Plxnb2 MGI:MGI:2154239|Ensembl:ENSMUSG00000036606|Vega:OTTMUSG00000021019 +140571 Plxnb3 MGI:MGI:2154240|Ensembl:ENSMUSG00000031385|Vega:OTTMUSG00000017705 +140573 D4Mon1 MGI:MGI:1926786 +140577 Ankrd6 MGI:MGI:2154278|Ensembl:ENSMUSG00000040183|Vega:OTTMUSG00000004975 +140579 Elmo2 MGI:MGI:2153045|Ensembl:ENSMUSG00000017670|Vega:OTTMUSG00000001171 +140580 Elmo1 MGI:MGI:2153044|Ensembl:ENSMUSG00000041112|Vega:OTTMUSG00000042551 +140626 T(2;10)67Gso MGI:MGI:2154471 +140629 Ubox5 MGI:MGI:2154658|Ensembl:ENSMUSG00000027300|Vega:OTTMUSG00000015515 +140630 Ube4a MGI:MGI:2154580|Ensembl:ENSMUSG00000059890|Vega:OTTMUSG00000030766 +140640 Fembm1 MGI:MGI:2154759 +140641 Fembm3 MGI:MGI:2154761 +140642 Fembm4 MGI:MGI:2154762 +140643 Fembm5 MGI:MGI:2154763 +140644 Fembm6 MGI:MGI:2154764 +140645 Fembm2 MGI:MGI:2154760 +140646 Fembm7 MGI:MGI:2154765 +140650 Leg1 MGI:MGI:1890583 +140651 Leg2 MGI:MGI:1890584 +140703 Emid1 MGI:MGI:2155091|Ensembl:ENSMUSG00000034164|Vega:OTTMUSG00000005081 +140709 Col26a1 MGI:MGI:2155345|Ensembl:ENSMUSG00000004415|Vega:OTTMUSG00000022688 +140721 Caskin2 MGI:MGI:2157062|Ensembl:ENSMUSG00000034471|Vega:OTTMUSG00000003534 +140723 Cacng5 MGI:MGI:2157946|Ensembl:ENSMUSG00000040373|Vega:OTTMUSG00000003104 +140740 Sec63 MGI:MGI:2155302|Ensembl:ENSMUSG00000019802|Vega:OTTMUSG00000019467 +140741 Gpr6 MGI:MGI:2155249|Ensembl:ENSMUSG00000046922|Vega:OTTMUSG00000063438 +140742 Sesn1 MGI:MGI:2155278|Ensembl:ENSMUSG00000038332|Vega:OTTMUSG00000020838 +140743 Rem2 MGI:MGI:2155260|Ensembl:ENSMUSG00000022176|Vega:OTTMUSG00000035271 +140762 C87926 MGI:MGI:2155334 +140765 Tmprss3 MGI:MGI:2155445|Ensembl:ENSMUSG00000024034|Vega:OTTMUSG00000020097 +140780 Bmp2k MGI:MGI:2155456|Ensembl:ENSMUSG00000034663|Vega:OTTMUSG00000021531 +140781 Myh7 MGI:MGI:2155600|Ensembl:ENSMUSG00000053093|Vega:OTTMUSG00000016385 +140792 Colec12 MGI:MGI:2152907|Ensembl:ENSMUSG00000036103 +140794 Pas3b MGI:MGI:2155631 +140795 P2ry14 MGI:MGI:2155705|Ensembl:ENSMUSG00000036381|Vega:OTTMUSG00000052404 +140796 Sluc2 MGI:MGI:2155621 +140797 Sluc3 MGI:MGI:2155622 +140798 Pas5 MGI:MGI:109195 +140799 Ramt1 MGI:MGI:2155670 +140806 Il25 MGI:MGI:2155888|Ensembl:ENSMUSG00000040770 +140810 Ttbk2 MGI:MGI:2155779|Ensembl:ENSMUSG00000090100|Vega:OTTMUSG00000015707 +140858 Wdr5 MGI:MGI:2155884|Ensembl:ENSMUSG00000026917|Vega:OTTMUSG00000012048 +140859 Nek8 MGI:MGI:1890646|Ensembl:ENSMUSG00000017405|Vega:OTTMUSG00000000109 +140887 Lnx2 MGI:MGI:2155959|Ensembl:ENSMUSG00000016520|Vega:OTTMUSG00000024626 +140889 D4Pot1 MGI:MGI:1891378 +140904 Caln1 MGI:MGI:2155987|Ensembl:ENSMUSG00000060371|Vega:OTTMUSG00000023954 +140917 Dclre1b MGI:MGI:2156057|Ensembl:ENSMUSG00000027845|Vega:OTTMUSG00000022447 +140918 Slc7a12 MGI:MGI:2156159|Ensembl:ENSMUSG00000039710|Vega:OTTMUSG00000026423 +140919 Slc17a6 MGI:MGI:2156052|Ensembl:ENSMUSG00000030500|Vega:OTTMUSG00000059014 +142681 Slc34a3 MGI:MGI:2159410|Ensembl:ENSMUSG00000006469|Vega:OTTMUSG00000011890 +142682 Zcchc14 MGI:MGI:2159407|Ensembl:ENSMUSG00000061410|Vega:OTTMUSG00000023426 +142687 Asb14 MGI:MGI:2655107|Ensembl:ENSMUSG00000021898|Vega:OTTMUSG00000035287 +142688 Asb13 MGI:MGI:2145525|Ensembl:ENSMUSG00000033781|Vega:OTTMUSG00000029821 +142980 Tlr3 MGI:MGI:2156367|Ensembl:ENSMUSG00000031639|Vega:OTTMUSG00000061136 +142981 Cbx3-ps2 MGI:MGI:1890539 +142983 Cbx3-ps1 MGI:MGI:1890538 +170439 Elovl6 MGI:MGI:2156528|Ensembl:ENSMUSG00000041220|Vega:OTTMUSG00000054039 +170441 Slc2a10 MGI:MGI:2156687|Ensembl:ENSMUSG00000027661|Vega:OTTMUSG00000001114 +170442 Bbox1 MGI:MGI:1891372|Ensembl:ENSMUSG00000041660|Vega:OTTMUSG00000015126 +170458 Gpha2 MGI:MGI:2156541|Ensembl:ENSMUSG00000024784|Vega:OTTMUSG00000018609 +170459 Stard4 MGI:MGI:2156764|Ensembl:ENSMUSG00000024378|Vega:OTTMUSG00000028069 +170460 Stard5 MGI:MGI:2156765|Ensembl:ENSMUSG00000046027|Vega:OTTMUSG00000027325 +170461 Stard6 MGI:MGI:2156774|Ensembl:ENSMUSG00000079608|Vega:OTTMUSG00000037152 +170472 Recql5 MGI:MGI:2156841|Ensembl:ENSMUSG00000020752|Vega:OTTMUSG00000003617 +170483 Grin3b MGI:MGI:2150393|Ensembl:ENSMUSG00000035745|Vega:OTTMUSG00000019135 +170484 Nphs2 MGI:MGI:2157018|Ensembl:ENSMUSG00000026602|Vega:OTTMUSG00000050345 +170571 Cntnap4 MGI:MGI:2183572|Ensembl:ENSMUSG00000031772|Vega:OTTMUSG00000030975 +170574 Sp7 MGI:MGI:2153568|Ensembl:ENSMUSG00000060284 +170624 Dep1 MGI:MGI:2157364 +170625 Snx18 MGI:MGI:2137642|Ensembl:ENSMUSG00000042364 +170638 Hpcal4 MGI:MGI:2157521|Ensembl:ENSMUSG00000046093|Vega:OTTMUSG00000008935 +170639 Olfr78 MGI:MGI:2157548|Ensembl:ENSMUSG00000043366|Vega:OTTMUSG00000060054 +170643 Kirrel MGI:MGI:1891396|Ensembl:ENSMUSG00000041734|Vega:OTTMUSG00000035037 +170644 Ubn1 MGI:MGI:1891307|Ensembl:ENSMUSG00000039473 +170645 Od MGI:MGI:1890757 +170646 Noa MGI:MGI:1891009 +170647 Onc1 MGI:MGI:1890595 +170648 Olfr138 MGI:MGI:2177521|Ensembl:ENSMUSG00000057443|Vega:OTTMUSG00000037362 +170650 Trm1 MGI:MGI:1890640 +170651 Krtap19-2 MGI:MGI:2157572|Ensembl:ENSMUSG00000057650 +170654 Krtap19-4 MGI:MGI:2157757|Ensembl:ENSMUSG00000043982 +170656 Krtap21-1 MGI:MGI:2157767|Ensembl:ENSMUSG00000058368 +170657 Krtap19-1 MGI:MGI:2157755|Ensembl:ENSMUSG00000060691 +170658 BC002163 MGI:MGI:3612445 +170660 Tmevp1 MGI:MGI:2157774 +170661 Lcho1 MGI:MGI:2137322 +170662 Lcho2 MGI:MGI:2137323 +170663 Lcho3 MGI:MGI:2137324 +170664 Lcho4 MGI:MGI:2137325 +170665 Pcho1 MGI:MGI:2137326 +170676 Peg10 MGI:MGI:2157785|Ensembl:ENSMUSG00000092035|Vega:OTTMUSG00000042254 +170677 Cdhr1 MGI:MGI:2157782|Ensembl:ENSMUSG00000021803 +170696 Trem5 MGI:MGI:2157853 +170697 Trem4 MGI:MGI:2157854 +170706 Tmem37 MGI:MGI:2157899|Ensembl:ENSMUSG00000050777|Vega:OTTMUSG00000022101 +170707 Usp48 MGI:MGI:2158502|Ensembl:ENSMUSG00000043411|Vega:OTTMUSG00000009759 +170711 Otud7a MGI:MGI:2158505|Ensembl:ENSMUSG00000033510|Vega:OTTMUSG00000027290 +170716 Cyp4f13 MGI:MGI:2158641|Ensembl:ENSMUSG00000024055|Vega:OTTMUSG00000032948 +170718 Idh3b MGI:MGI:2158650|Ensembl:ENSMUSG00000027406|Vega:OTTMUSG00000015521 +170719 Oxr1 MGI:MGI:2179326|Ensembl:ENSMUSG00000022307 +170720 Card14 MGI:MGI:2386258|Ensembl:ENSMUSG00000013483|Vega:OTTMUSG00000003913 +170721 Papln MGI:MGI:2386139|Ensembl:ENSMUSG00000021223|Vega:OTTMUSG00000027564 +170722 Nxf7 MGI:MGI:2159343|Ensembl:ENSMUSG00000031410|Vega:OTTMUSG00000018744 +170725 Capn8 MGI:MGI:2181366|Ensembl:ENSMUSG00000038599|Vega:OTTMUSG00000050481 +170728 Rtn4ip1 MGI:MGI:2178759|Ensembl:ENSMUSG00000019864|Vega:OTTMUSG00000023044 +170729 Scrt1 MGI:MGI:2176606|Ensembl:ENSMUSG00000048385 +170731 Mfn2 MGI:MGI:2442230|Ensembl:ENSMUSG00000029020|Vega:OTTMUSG00000010659 +170732 Trhr2 MGI:MGI:2177284|Ensembl:ENSMUSG00000039079|Vega:OTTMUSG00000027550 +170733 Klra17 MGI:MGI:2180674|Ensembl:ENSMUSG00000014543|Vega:OTTMUSG00000026518 +170734 Zscan5b MGI:MGI:2159640|Ensembl:ENSMUSG00000058028|Vega:OTTMUSG00000027096 +170735 Arr3 MGI:MGI:2159617|Ensembl:ENSMUSG00000060890|Vega:OTTMUSG00000018283 +170736 Parvb MGI:MGI:2153063|Ensembl:ENSMUSG00000022438|Vega:OTTMUSG00000026115 +170737 Znrf1 MGI:MGI:2177308|Ensembl:ENSMUSG00000033545|Vega:OTTMUSG00000038178 +170738 Kcnh7 MGI:MGI:2159566|Ensembl:ENSMUSG00000059742|Vega:OTTMUSG00000012800 +170740 Zfp287 MGI:MGI:2176561|Ensembl:ENSMUSG00000005267|Vega:OTTMUSG00000005869 +170741 Pilrb1 MGI:MGI:2450532|Ensembl:ENSMUSG00000066684|Vega:OTTMUSG00000054648 +170742 Sertad3 MGI:MGI:2180697|Ensembl:ENSMUSG00000055200|Vega:OTTMUSG00000058610 +170743 Tlr7 MGI:MGI:2176882|Ensembl:ENSMUSG00000044583|Vega:OTTMUSG00000019578 +170744 Tlr8 MGI:MGI:2176887|Ensembl:ENSMUSG00000040522|Vega:OTTMUSG00000019575 +170745 Xpnpep2 MGI:MGI:2180001|Ensembl:ENSMUSG00000037005|Vega:OTTMUSG00000017507 +170748 Smco4 MGI:MGI:3039636|Ensembl:ENSMUSG00000058173|Vega:OTTMUSG00000062296 +170749 Mtmr4 MGI:MGI:2180699|Ensembl:ENSMUSG00000018401|Vega:OTTMUSG00000001293 +170750 Xpnpep1 MGI:MGI:2180003|Ensembl:ENSMUSG00000025027|Vega:OTTMUSG00000043312 +170752 Bco2 MGI:MGI:2177469|Ensembl:ENSMUSG00000032066|Vega:OTTMUSG00000030004 +170753 Zfp704 MGI:MGI:2180715|Ensembl:ENSMUSG00000040209|Vega:OTTMUSG00000051452 +170755 Sgk3 MGI:MGI:2182368|Ensembl:ENSMUSG00000025915|Vega:OTTMUSG00000045250 +170756 Slc8b1 MGI:MGI:2180781|Ensembl:ENSMUSG00000032754|Vega:OTTMUSG00000025317 +170757 Adgrl4 MGI:MGI:2655562|Ensembl:ENSMUSG00000039167|Vega:OTTMUSG00000023660 +170758 Rac3 MGI:MGI:2180784|Ensembl:ENSMUSG00000018012|Vega:OTTMUSG00000004093 +170759 Atp13a1 MGI:MGI:2180801|Ensembl:ENSMUSG00000031862 +170760 Acbd3 MGI:MGI:2181074|Ensembl:ENSMUSG00000026499|Vega:OTTMUSG00000050453 +170761 Pdzd3 MGI:MGI:2429554|Ensembl:ENSMUSG00000032105|Vega:OTTMUSG00000063216 +170762 Nup155 MGI:MGI:2181182|Ensembl:ENSMUSG00000022142 +170763 Zfp87 MGI:MGI:107768|Ensembl:ENSMUSG00000097333|Vega:OTTMUSG00000042797 +170765 Ripply3 MGI:MGI:2181192|Ensembl:ENSMUSG00000022941|Vega:OTTMUSG00000019884 +170767 Rfxap MGI:MGI:2180854|Ensembl:ENSMUSG00000036615|Vega:OTTMUSG00000043569 +170768 Pfkfb3 MGI:MGI:2181202|Ensembl:ENSMUSG00000026773|Vega:OTTMUSG00000011314 +170769 Gm4740 MGI:MGI:3648965 +170770 Bbc3 MGI:MGI:2181667|Ensembl:ENSMUSG00000002083|Vega:OTTMUSG00000022267 +170771 Khdrbs2 MGI:MGI:2159649|Ensembl:ENSMUSG00000026058|Vega:OTTMUSG00000048923 +170772 Glcci1 MGI:MGI:2179717|Ensembl:ENSMUSG00000029638|Vega:OTTMUSG00000030314 +170776 Cd209c MGI:MGI:2157945|Ensembl:ENSMUSG00000040165|Vega:OTTMUSG00000027103 +170779 Cd209d MGI:MGI:2157947|Ensembl:ENSMUSG00000031495|Vega:OTTMUSG00000059325 +170780 Cd209e MGI:MGI:2157948|Ensembl:ENSMUSG00000040197|Vega:OTTMUSG00000027102 +170786 Cd209a MGI:MGI:2157942|Ensembl:ENSMUSG00000031494|Vega:OTTMUSG00000059324 +170787 Hdac10 MGI:MGI:2158340|Ensembl:ENSMUSG00000062906|Vega:OTTMUSG00000017283 +170788 Crb1 MGI:MGI:2136343|Ensembl:ENSMUSG00000063681|Vega:OTTMUSG00000033974 +170789 Acot8 MGI:MGI:2158201|Ensembl:ENSMUSG00000017307|Vega:OTTMUSG00000001161 +170790 Mlc1 MGI:MGI:2157910|Ensembl:ENSMUSG00000035805|Vega:OTTMUSG00000020982 +170791 Rbm39 MGI:MGI:2157953|Ensembl:ENSMUSG00000027620|Vega:OTTMUSG00000016122 +170792 Ptz1a MGI:MGI:2158338 +170793 Ptz1b MGI:MGI:2158339 +170797 Sez2 MGI:MGI:2158383 +170798 AY036118 MGI:MGI:2158419 +170799 Rtkn2 MGI:MGI:2158417|Ensembl:ENSMUSG00000037846|Vega:OTTMUSG00000031778 +170800 Cdcs1 MGI:MGI:1927809 +170801 Idd5.1 MGI:MGI:2158421 +170802 Idd5.2 MGI:MGI:2158434 +170803 Cdcs2 MGI:MGI:2158450 +170804 Cdcs3 MGI:MGI:2158451 +170805 Cdcs4 MGI:MGI:2158452 +170806 Cdcs5 MGI:MGI:2158453 +170807 Cdcs6 MGI:MGI:2158454 +170812 Ahsp MGI:MGI:2158492 +170813 Ms4a3 MGI:MGI:2158468|Ensembl:ENSMUSG00000024681|Vega:OTTMUSG00000047243 +170822 Usp33 MGI:MGI:2159711|Ensembl:ENSMUSG00000025437|Vega:OTTMUSG00000027542 +170823 Glmn MGI:MGI:2141180|Ensembl:ENSMUSG00000029276|Vega:OTTMUSG00000023402 +170826 Ppargc1b MGI:MGI:2444934|Ensembl:ENSMUSG00000033871|Vega:OTTMUSG00000024012 +170828 Vgll1 MGI:MGI:2655768|Ensembl:ENSMUSG00000031131|Vega:OTTMUSG00000017789 +170829 Tram2 MGI:MGI:1924817|Ensembl:ENSMUSG00000041779|Vega:OTTMUSG00000026556 +170833 Hook2 MGI:MGI:2181664|Ensembl:ENSMUSG00000052566|Vega:OTTMUSG00000061398 +170834 Oosp1 MGI:MGI:2149290|Ensembl:ENSMUSG00000041857|Vega:OTTMUSG00000028279 +170835 Inpp5j MGI:MGI:2158663|Ensembl:ENSMUSG00000034570|Vega:OTTMUSG00000005023 +170930 Sumo2 MGI:MGI:2158813|Ensembl:ENSMUSG00000020738|Vega:OTTMUSG00000003474 +170935 Grid2ip MGI:MGI:2176213|Ensembl:ENSMUSG00000010825|Vega:OTTMUSG00000026813 +170936 Zfp369 MGI:MGI:2176229|Ensembl:ENSMUSG00000021514|Vega:OTTMUSG00000032928 +170938 Zfp617 MGI:MGI:2684459|Ensembl:ENSMUSG00000066880|Vega:OTTMUSG00000031324 +170939 Krtap19-9b MGI:MGI:2181750|Ensembl:ENSMUSG00000057174 +170942 Erdr1 MGI:MGI:2384747|Ensembl:ENSMUSG00000096768 +170947 Myoz3 MGI:MGI:2179296|Ensembl:ENSMUSG00000049173|Vega:OTTMUSG00000028146 +170952 Prima1 MGI:MGI:1926097|Ensembl:ENSMUSG00000041669|Vega:OTTMUSG00000025404 +171032 Chab1 MGI:MGI:2137315 +171033 Chab3 MGI:MGI:2137317 +171034 Chab6 MGI:MGI:2137320 +171035 Chab7 MGI:MGI:2137321 +171036 Chab2 MGI:MGI:2137316 +171037 Chab4 MGI:MGI:2137318 +171038 Chab5 MGI:MGI:2137319 +171095 Il17rc MGI:MGI:2159336|Ensembl:ENSMUSG00000030281|Vega:OTTMUSG00000024163 +171166 Mcoln3 MGI:MGI:1890500|Ensembl:ENSMUSG00000036853|Vega:OTTMUSG00000026569 +171167 Fut10 MGI:MGI:2384748|Ensembl:ENSMUSG00000046152|Vega:OTTMUSG00000026250 +171168 Acer1 MGI:MGI:2181962|Ensembl:ENSMUSG00000045019 +171170 Mbnl3 MGI:MGI:2444912|Ensembl:ENSMUSG00000036109|Vega:OTTMUSG00000017478 +171171 Ntng2 MGI:MGI:2159341|Ensembl:ENSMUSG00000035513|Vega:OTTMUSG00000011855 +171180 Syt12 MGI:MGI:2159601|Ensembl:ENSMUSG00000049303|Vega:OTTMUSG00000028326 +171183 Vmn1r37 MGI:MGI:2159442|Ensembl:ENSMUSG00000057612|Vega:OTTMUSG00000040012 +171184 Vmn1r36 MGI:MGI:2159443|Ensembl:ENSMUSG00000093764|Vega:OTTMUSG00000040011 +171185 Vmn1r35 MGI:MGI:2159444|Ensembl:ENSMUSG00000060699|Vega:OTTMUSG00000040010 +171186 Vmn1r38 MGI:MGI:2159445|Ensembl:ENSMUSG00000093632|Vega:OTTMUSG00000040014 +171187 Vmn1r33 MGI:MGI:2159450|Ensembl:ENSMUSG00000059375|Vega:OTTMUSG00000040000 +171188 Vmn1r32 MGI:MGI:2159451|Ensembl:ENSMUSG00000062905|Vega:OTTMUSG00000039999 +171189 Vmn1r17 MGI:MGI:2159452|Ensembl:ENSMUSG00000093411|Vega:OTTMUSG00000039925 +171190 Vmn1r26 MGI:MGI:2159453|Ensembl:ENSMUSG00000048697|Vega:OTTMUSG00000039950 +171191 Vmn1r24 MGI:MGI:2159454|Ensembl:ENSMUSG00000093451|Vega:OTTMUSG00000039948 +171192 Vmn1r5 MGI:MGI:2159455|Ensembl:ENSMUSG00000090346|Vega:OTTMUSG00000039876 +171193 Vmn1r6 MGI:MGI:2159456|Ensembl:ENSMUSG00000058923|Vega:OTTMUSG00000039877 +171194 Vmn1r4 MGI:MGI:2159457|Ensembl:ENSMUSG00000071893|Vega:OTTMUSG00000039875 +171195 Vmn1r30 MGI:MGI:2159458|Ensembl:ENSMUSG00000095670|Vega:OTTMUSG00000039992 +171196 Vmn1r22 MGI:MGI:2159459|Ensembl:ENSMUSG00000093501|Vega:OTTMUSG00000039937 +171197 Vmn1r23 MGI:MGI:2159460|Ensembl:ENSMUSG00000093376|Vega:OTTMUSG00000039946 +171198 Vmn1r28 MGI:MGI:2159461|Ensembl:ENSMUSG00000094291|Vega:OTTMUSG00000039988 +171199 Vmn1r18 MGI:MGI:2159462|Ensembl:ENSMUSG00000091382|Vega:OTTMUSG00000039926 +171200 Vmn1r19 MGI:MGI:2159463|Ensembl:ENSMUSG00000068426|Vega:OTTMUSG00000039929 +171201 Vmn1r21 MGI:MGI:2159464|Ensembl:ENSMUSG00000058588|Vega:OTTMUSG00000039935 +171202 Vmn1r16 MGI:MGI:2159465|Ensembl:ENSMUSG00000093523|Vega:OTTMUSG00000039924 +171203 Vmn1r9 MGI:MGI:2159466|Ensembl:ENSMUSG00000091541|Vega:OTTMUSG00000039879 +171205 Vmn1r8 MGI:MGI:2159469|Ensembl:ENSMUSG00000061208|Vega:OTTMUSG00000039878 +171206 Vmn1r27 MGI:MGI:2159470|Ensembl:ENSMUSG00000071428|Vega:OTTMUSG00000039983 +171207 Arhgap4 MGI:MGI:2159577|Ensembl:ENSMUSG00000031389|Vega:OTTMUSG00000017679 +171209 Asic3 MGI:MGI:2159339|Ensembl:ENSMUSG00000038276|Vega:OTTMUSG00000053655 +171210 Acot2 MGI:MGI:2159605|Ensembl:ENSMUSG00000021226|Vega:OTTMUSG00000027592 +171211 Edaradd MGI:MGI:1931001|Ensembl:ENSMUSG00000095105 +171212 Galnt10 MGI:MGI:1890480|Ensembl:ENSMUSG00000020520|Vega:OTTMUSG00000005711 +171213 Radpf1 MGI:MGI:2155166 +171214 Bplpf1 MGI:MGI:2155833 +171215 Bplpf2 MGI:MGI:2155834 +171216 Alcw4 MGI:MGI:2159373 +171217 Pcpila2 MGI:MGI:2159378 +171218 Pcpila1 MGI:MGI:2159377 +171219 Pcpila3 MGI:MGI:2159379 +171224 Vmn1r229 MGI:MGI:2159615|Ensembl:ENSMUSG00000061150|Vega:OTTMUSG00000039815 +171225 Vmn1r226 MGI:MGI:2159616|Ensembl:ENSMUSG00000042848|Vega:OTTMUSG00000039786 +171226 Vmn1r228 MGI:MGI:2159624|Ensembl:ENSMUSG00000060245|Vega:OTTMUSG00000039814 +171227 Vmn1r232 MGI:MGI:2159625|Ensembl:ENSMUSG00000062165|Vega:OTTMUSG00000039818 +171228 Vmn1r225 MGI:MGI:2159626|Ensembl:ENSMUSG00000043537|Vega:OTTMUSG00000039782 +171229 Vmn1r227 MGI:MGI:2159627 +171230 Vmn1r231 MGI:MGI:2159628|Ensembl:ENSMUSG00000050933|Vega:OTTMUSG00000039817 +171231 Vmn1r230 MGI:MGI:2159629|Ensembl:ENSMUSG00000045417|Vega:OTTMUSG00000039816 +171232 Vmn1r234 MGI:MGI:2159635|Ensembl:ENSMUSG00000057203|Vega:OTTMUSG00000039891 +171233 Vmn1r235 MGI:MGI:2159636|Ensembl:ENSMUSG00000050102|Vega:OTTMUSG00000036568 +171234 Vmn1r237 MGI:MGI:2159637|Ensembl:ENSMUSG00000058030|Vega:OTTMUSG00000039896 +171235 Vmn1r236 MGI:MGI:2159638|Ensembl:ENSMUSG00000054142|Vega:OTTMUSG00000039895 +171236 Vmn1r233 MGI:MGI:2159639|Ensembl:ENSMUSG00000045575|Vega:OTTMUSG00000039821 +171237 Vmn1r73 MGI:MGI:2159641|Ensembl:ENSMUSG00000051687|Vega:OTTMUSG00000038274 +171238 Vmn1r80 MGI:MGI:2159642|Ensembl:ENSMUSG00000057161|Vega:OTTMUSG00000038257 +171239 Vmn1r76 MGI:MGI:2159643|Ensembl:ENSMUSG00000045713|Vega:OTTMUSG00000038246 +171240 Vmn1r74 MGI:MGI:2159644|Ensembl:ENSMUSG00000047655|Vega:OTTMUSG00000038276 +171241 Vmn1r75 MGI:MGI:2159645|Ensembl:ENSMUSG00000043308|Vega:OTTMUSG00000038244 +171242 Vmn1r78 MGI:MGI:2159646|Ensembl:ENSMUSG00000061602|Vega:OTTMUSG00000038255 +171243 Vmn1r83 MGI:MGI:2159647|Ensembl:ENSMUSG00000066804|Vega:OTTMUSG00000038262 +171244 Vmn1r81 MGI:MGI:2159648|Ensembl:ENSMUSG00000094078|Vega:OTTMUSG00000038260 +171245 Vmn1r-ps103 MGI:MGI:2159658 +171246 Vmn1r200 MGI:MGI:2159660|Ensembl:ENSMUSG00000101073|Vega:OTTMUSG00000000495 +171247 Vmn1r199 MGI:MGI:2159662|Ensembl:ENSMUSG00000069292|Vega:OTTMUSG00000000484 +171248 Vmn1r214 MGI:MGI:2159663|Ensembl:ENSMUSG00000061829|Vega:OTTMUSG00000000532 +171249 Vmn1r213 MGI:MGI:2159664|Ensembl:ENSMUSG00000060024|Vega:OTTMUSG00000000533 +171250 Vmn1r206 MGI:MGI:2159665|Ensembl:ENSMUSG00000101578|Vega:OTTMUSG00000000507 +171251 Vmn1r205 MGI:MGI:2159667|Ensembl:ENSMUSG00000100296|Vega:OTTMUSG00000000508 +171252 Vmn1r208 MGI:MGI:2159668|Ensembl:ENSMUSG00000071493|Vega:OTTMUSG00000000518 +171253 Vmn1r215 MGI:MGI:2159687|Ensembl:ENSMUSG00000099917|Vega:OTTMUSG00000000531 +171254 Vmn1r198 MGI:MGI:2159689|Ensembl:ENSMUSG00000095125|Vega:OTTMUSG00000000486 +171255 Vmn1r201 MGI:MGI:2159690|Ensembl:ENSMUSG00000094898|Vega:OTTMUSG00000000499 +171256 Vmn1r218 MGI:MGI:2159691|Ensembl:ENSMUSG00000060490|Vega:OTTMUSG00000000534 +171257 Vmn1r195 MGI:MGI:2159692|Ensembl:ENSMUSG00000069296|Vega:OTTMUSG00000000489 +171258 Vmn1r202 MGI:MGI:2159693|Ensembl:ENSMUSG00000094379|Vega:OTTMUSG00000000501 +171259 Vmn1r193 MGI:MGI:2159695|Ensembl:ENSMUSG00000046932|Vega:OTTMUSG00000000481 +171260 Vmn1r89 MGI:MGI:2159697|Ensembl:ENSMUSG00000095629|Vega:OTTMUSG00000038216 +171261 Vmn1r87 MGI:MGI:2159698|Ensembl:ENSMUSG00000070815|Vega:OTTMUSG00000038214 +171262 Vmn1r70 MGI:MGI:2159699|Ensembl:ENSMUSG00000045340|Vega:OTTMUSG00000038519 +171263 Vmn1r67 MGI:MGI:2159632|Ensembl:ENSMUSG00000046716|Vega:OTTMUSG00000038514 +171264 Vmn1r66 MGI:MGI:2159633|Ensembl:ENSMUSG00000043066|Vega:OTTMUSG00000038511 +171265 Vmn1r185 MGI:MGI:2159634|Ensembl:ENSMUSG00000091924|Vega:OTTMUSG00000037988 +171266 V1rg10 MGI:MGI:2159654 +171267 Vmn1r84 MGI:MGI:2159655|Ensembl:ENSMUSG00000066803|Vega:OTTMUSG00000038263 +171268 Vmn1r82 MGI:MGI:2159656|Ensembl:ENSMUSG00000058132|Vega:OTTMUSG00000038261 +171269 Vmn1r210 MGI:MGI:2159673|Ensembl:ENSMUSG00000061296|Vega:OTTMUSG00000000516 +171270 Vmn1r203 MGI:MGI:2159674|Ensembl:ENSMUSG00000069289|Vega:OTTMUSG00000000498 +171271 Vmn1r220 MGI:MGI:2159675|Ensembl:ENSMUSG00000096099|Vega:OTTMUSG00000000539 +171272 Vmn1r219 MGI:MGI:2159676|Ensembl:ENSMUSG00000061376|Vega:OTTMUSG00000000540 +171273 Vmn1r217 MGI:MGI:2159677|Ensembl:ENSMUSG00000094600|Vega:OTTMUSG00000000536 +171274 Vmn1r222 MGI:MGI:2159679|Ensembl:ENSMUSG00000061022|Vega:OTTMUSG00000000550 +171275 Vmn1r212 MGI:MGI:2159683|Ensembl:ENSMUSG00000071490|Vega:OTTMUSG00000000521 +171276 V1rh19 MGI:MGI:2159684 +171277 Vmn1r211 MGI:MGI:2159685|Ensembl:ENSMUSG00000063998|Vega:OTTMUSG00000000517 +171278 Vmn1r197 MGI:MGI:2159686|Ensembl:ENSMUSG00000069294|Vega:OTTMUSG00000000488 +171279 Vmn1r216 MGI:MGI:2159696|Ensembl:ENSMUSG00000057799|Vega:OTTMUSG00000000535 +171281 Acot3 MGI:MGI:2159619|Ensembl:ENSMUSG00000021228|Vega:OTTMUSG00000027601 +171282 Acot4 MGI:MGI:2159621|Ensembl:ENSMUSG00000052392|Vega:OTTMUSG00000027597 +171283 Havcr1 MGI:MGI:2159680|Ensembl:ENSMUSG00000040405|Vega:OTTMUSG00000005506 +171284 Timd2 MGI:MGI:2159681|Ensembl:ENSMUSG00000040413|Vega:OTTMUSG00000005505 +171285 Havcr2 MGI:MGI:2159682|Ensembl:ENSMUSG00000020399|Vega:OTTMUSG00000005503 +171286 Slc12a8 MGI:MGI:2443672|Ensembl:ENSMUSG00000035506|Vega:OTTMUSG00000027311 +171382 Trpm8 MGI:MGI:2181435|Ensembl:ENSMUSG00000036251|Vega:OTTMUSG00000019582 +171388 Bnipl MGI:MGI:2384749|Ensembl:ENSMUSG00000028115|Vega:OTTMUSG00000022357 +171395 Pkd1l1 MGI:MGI:2156538|Ensembl:ENSMUSG00000046634|Vega:OTTMUSG00000005143 +171405 Slc22a27 MGI:MGI:3042283|Ensembl:ENSMUSG00000067656|Vega:OTTMUSG00000044358 +171429 Slc26a6 MGI:MGI:2159728|Ensembl:ENSMUSG00000023259|Vega:OTTMUSG00000047370 +171430 D19Char27 MGI:MGI:2159726 +171463 Il17rd MGI:MGI:2159727|Ensembl:ENSMUSG00000040717 +171464 Dbil5-ps MGI:MGI:2159731 +171469 Gpr37l1 MGI:MGI:1928503|Ensembl:ENSMUSG00000026424|Vega:OTTMUSG00000022102 +171470 D8Ertd28e MGI:MGI:2175899 +171486 Cd99l2 MGI:MGI:2177151|Ensembl:ENSMUSG00000035776|Vega:OTTMUSG00000017999 +171504 Apobr MGI:MGI:2176230|Ensembl:ENSMUSG00000042759|Vega:OTTMUSG00000029445 +171506 H1foo MGI:MGI:2176207|Ensembl:ENSMUSG00000042279|Vega:OTTMUSG00000033828 +171507 Lith5 MGI:MGI:2176161 +171508 Creld1 MGI:MGI:2152539|Ensembl:ENSMUSG00000030284|Vega:OTTMUSG00000023299 +171509 Gasa3 MGI:MGI:2176188 +171510 Gasa4 MGI:MGI:2176189 +171530 Ucn2 MGI:MGI:2176375|Ensembl:ENSMUSG00000049699|Vega:OTTMUSG00000051196 +171531 Mlph MGI:MGI:2176380|Ensembl:ENSMUSG00000026303|Vega:OTTMUSG00000022397 +171532 AF180010 MGI:MGI:2136211 +171535 AF180007 MGI:MGI:2136250 +171536 AF179935 MGI:MGI:2136251 +171537 AF179997 MGI:MGI:2136252 +171539 AF179939 MGI:MGI:2136254 +171540 AF179933 MGI:MGI:2136255 +171541 AF179942 MGI:MGI:2136256 +171543 Bmf MGI:MGI:2176433|Ensembl:ENSMUSG00000040093|Vega:OTTMUSG00000015369 +171544 Huc1 MGI:MGI:2176300 +171545 Huc2 MGI:MGI:2176304 +171561 Murrs2 MGI:MGI:2176474 +171567 Nme7 MGI:MGI:2449121|Ensembl:ENSMUSG00000026575|Vega:OTTMUSG00000050838 +171580 Mical1 MGI:MGI:2385847|Ensembl:ENSMUSG00000019823|Vega:OTTMUSG00000030589 +171584 Nss1 MGI:MGI:2176545 +171588 Gm38402 MGI:MGI:5621287|Ensembl:ENSMUSG00000083674 +191577 cir MGI:MGI:2176711 +191578 Helq MGI:MGI:2176740|Ensembl:ENSMUSG00000035266|Vega:OTTMUSG00000026173 +192098 Stheal1 MGI:MGI:2176905 +192099 Stheal2 MGI:MGI:2176906 +192100 Stheal3 MGI:MGI:2176907 +192101 Stheal4 MGI:MGI:2176908 +192102 Stheal5 MGI:MGI:2176909 +192103 Stheal6 MGI:MGI:2176910 +192104 Stheal7 MGI:MGI:2176911 +192105 Stheal8 MGI:MGI:2176913 +192106 Stheal9 MGI:MGI:2176914 +192113 Atp12a MGI:MGI:1926943|Ensembl:ENSMUSG00000022229 +192118 Lith4 MGI:MGI:1891059 +192119 Dicer1 MGI:MGI:2177178|Ensembl:ENSMUSG00000041415 +192120 Bspry MGI:MGI:2177191|Ensembl:ENSMUSG00000028392|Vega:OTTMUSG00000000309 +192136 Sugct MGI:MGI:1923221|Ensembl:ENSMUSG00000055137 +192140 Tmc2 MGI:MGI:2151017|Ensembl:ENSMUSG00000060332|Vega:OTTMUSG00000015502 +192156 Mvd MGI:MGI:2179327|Ensembl:ENSMUSG00000006517|Vega:OTTMUSG00000061847 +192157 Socs7 MGI:MGI:2651588|Ensembl:ENSMUSG00000038485|Vega:OTTMUSG00000002672 +192159 Prpf8 MGI:MGI:2179381|Ensembl:ENSMUSG00000020850|Vega:OTTMUSG00000006208 +192160 Casc3 MGI:MGI:2179723|Ensembl:ENSMUSG00000078676|Vega:OTTMUSG00000006456 +192161 Pcdha9 MGI:MGI:2447322|Ensembl:ENSMUSG00000103770|Vega:OTTMUSG00000050622 +192162 Pcdha@ - +192163 Pcdha3 MGI:MGI:2447313|Ensembl:ENSMUSG00000102312|Vega:OTTMUSG00000050587 +192164 Pcdha12 MGI:MGI:1298370|Ensembl:ENSMUSG00000103310|Vega:OTTMUSG00000050627 +192166 Sardh MGI:MGI:2183102|Ensembl:ENSMUSG00000009614|Vega:OTTMUSG00000012037 +192167 Nlgn1 MGI:MGI:2179435|Ensembl:ENSMUSG00000063887|Vega:OTTMUSG00000051161 +192169 Ufsp2 MGI:MGI:1913679|Ensembl:ENSMUSG00000031634|Vega:OTTMUSG00000023223 +192170 Eif4a3 MGI:MGI:1923731|Ensembl:ENSMUSG00000025580|Vega:OTTMUSG00000003807 +192173 Mcrip1 MGI:MGI:2384752|Ensembl:ENSMUSG00000061111|Vega:OTTMUSG00000004273 +192174 Rwdd4a MGI:MGI:2681000|Ensembl:ENSMUSG00000031568|Vega:OTTMUSG00000037696 +192176 Flna MGI:MGI:95556|Ensembl:ENSMUSG00000031328|Vega:OTTMUSG00000016503 +192185 Nadk MGI:MGI:2183149|Ensembl:ENSMUSG00000029063|Vega:OTTMUSG00000010726 +192187 Stab1 MGI:MGI:2178742|Ensembl:ENSMUSG00000042286|Vega:OTTMUSG00000033286 +192188 Stab2 MGI:MGI:2178743|Ensembl:ENSMUSG00000035459 +192190 Pkhd1l1 MGI:MGI:2183153|Ensembl:ENSMUSG00000038725|Vega:OTTMUSG00000060491 +192191 Med9 MGI:MGI:2183151|Ensembl:ENSMUSG00000061650|Vega:OTTMUSG00000008098 +192192 Shkbp1 MGI:MGI:2385803|Ensembl:ENSMUSG00000089832|Vega:OTTMUSG00000023744 +192193 Edem1 MGI:MGI:2180139|Ensembl:ENSMUSG00000030104|Vega:OTTMUSG00000056450 +192194 Btnl10 MGI:MGI:2182073|Ensembl:ENSMUSG00000020490|Vega:OTTMUSG00000005775 +192195 Ash1l MGI:MGI:2183158|Ensembl:ENSMUSG00000028053|Vega:OTTMUSG00000047367 +192196 Luc7l2 MGI:MGI:2183260|Ensembl:ENSMUSG00000029823|Vega:OTTMUSG00000034253 +192197 Bcas3 MGI:MGI:2385848|Ensembl:ENSMUSG00000059439|Vega:OTTMUSG00000001026 +192198 Lrrc4 MGI:MGI:2182081|Ensembl:ENSMUSG00000049939|Vega:OTTMUSG00000023270 +192199 Rspo1 MGI:MGI:2183426|Ensembl:ENSMUSG00000028871|Vega:OTTMUSG00000009245 +192200 Wfdc12 MGI:MGI:2183434|Ensembl:ENSMUSG00000042845|Vega:OTTMUSG00000001077 +192201 Wfdc15b MGI:MGI:2445041|Ensembl:ENSMUSG00000018211|Vega:OTTMUSG00000001082 +192202 Tlag2 MGI:MGI:2177626 +192212 Prom2 MGI:MGI:2138997|Ensembl:ENSMUSG00000027376|Vega:OTTMUSG00000016031 +192216 Tmem47 MGI:MGI:2177570|Ensembl:ENSMUSG00000025666|Vega:OTTMUSG00000017841 +192231 Hexim1 MGI:MGI:2385923|Ensembl:ENSMUSG00000048878|Vega:OTTMUSG00000003296 +192232 Hps4 MGI:MGI:2177742|Ensembl:ENSMUSG00000042328|Vega:OTTMUSG00000023434 +192236 Hps1 MGI:MGI:2177763|Ensembl:ENSMUSG00000025188|Vega:OTTMUSG00000032530 +192285 Phf21a MGI:MGI:2384756|Ensembl:ENSMUSG00000058318|Vega:OTTMUSG00000014393 +192287 Slc25a36 MGI:MGI:1924909|Ensembl:ENSMUSG00000032449|Vega:OTTMUSG00000031601 +192289 Tmlhe MGI:MGI:2180203|Ensembl:ENSMUSG00000079834 +192292 Nrbp1 MGI:MGI:2183436|Ensembl:ENSMUSG00000029148|Vega:OTTMUSG00000022515 +192344 NEWENTRY - +192650 Cabp7 MGI:MGI:2183437|Ensembl:ENSMUSG00000009075|Vega:OTTMUSG00000005069 +192651 Zfp286 MGI:MGI:2384758|Ensembl:ENSMUSG00000047342|Vega:OTTMUSG00000005873 +192652 Wdr81 MGI:MGI:2681828|Ensembl:ENSMUSG00000045374|Vega:OTTMUSG00000006200 +192653 Ttc36 MGI:MGI:2384760|Ensembl:ENSMUSG00000039438|Vega:OTTMUSG00000063364 +192654 Pla2g15 MGI:MGI:2178076|Ensembl:ENSMUSG00000031903|Vega:OTTMUSG00000061943 +192656 Ripk2 MGI:MGI:1891456|Ensembl:ENSMUSG00000041135|Vega:OTTMUSG00000004662 +192657 Ell2 MGI:MGI:2183438|Ensembl:ENSMUSG00000001542 +192658 Rfpl4 MGI:MGI:2149590|Ensembl:ENSMUSG00000035191|Vega:OTTMUSG00000059860 +192660 Sryip2 MGI:MGI:2178114 +192661 Sryip3 MGI:MGI:2178115 +192662 Arhgdia MGI:MGI:2178103|Ensembl:ENSMUSG00000025132|Vega:OTTMUSG00000004092 +192663 Abcg4 MGI:MGI:1890594|Ensembl:ENSMUSG00000032131|Vega:OTTMUSG00000029282 +192678 Rassf3 MGI:MGI:2179722|Ensembl:ENSMUSG00000025795 +192682 Pcdhg@ - +192734 Lrrc75b MGI:MGI:2143657|Ensembl:ENSMUSG00000046807|Vega:OTTMUSG00000046607 +192775 Kcnh6 MGI:MGI:2684139|Ensembl:ENSMUSG00000001901|Vega:OTTMUSG00000002939 +192786 Rapgef6 MGI:MGI:2384761|Ensembl:ENSMUSG00000037533|Vega:OTTMUSG00000005672 +192852 Lrrc3c MGI:MGI:2684858|Ensembl:ENSMUSG00000086545|Vega:OTTMUSG00000006391 +192885 BC005512 MGI:MGI:2682292 +192895 Gm12180 MGI:MGI:3651495 +192897 Itgb4 MGI:MGI:96613|Ensembl:ENSMUSG00000020758|Vega:OTTMUSG00000003650 +192950 Nacad MGI:MGI:3603030|Ensembl:ENSMUSG00000041073|Vega:OTTMUSG00000005121 +192970 Dhrs11 MGI:MGI:2652816|Ensembl:ENSMUSG00000034449|Vega:OTTMUSG00000000981 +192976 Lrrc75a MGI:MGI:2682293|Ensembl:ENSMUSG00000046417|Vega:OTTMUSG00000005865 +192986 Cyb5d2 MGI:MGI:2684848|Ensembl:ENSMUSG00000057778|Vega:OTTMUSG00000006112 +193003 Pirt MGI:MGI:2443635|Ensembl:ENSMUSG00000048070|Vega:OTTMUSG00000005913 +193022 Gm53 MGI:MGI:2684899 +193034 Trpv1 MGI:MGI:1341787|Ensembl:ENSMUSG00000005952|Vega:OTTMUSG00000006125 +193043 Zfp3 MGI:MGI:99177|Ensembl:ENSMUSG00000043602|Vega:OTTMUSG00000006064 +193053 Olfr384 MGI:MGI:3030218|Ensembl:ENSMUSG00000060335|Vega:OTTMUSG00000012461 +193079 Gm12332 MGI:MGI:3651128 +193116 Slu7 MGI:MGI:2385598|Ensembl:ENSMUSG00000020409|Vega:OTTMUSG00000005459 +193217 BC018473 MGI:MGI:3039625 +193280 C030037D09Rik MGI:MGI:1924865 +193286 BC049762 MGI:MGI:3039622|Ensembl:ENSMUSG00000045942|Vega:OTTMUSG00000005599 +193322 Oog1 MGI:MGI:2679150|Ensembl:ENSMUSG00000096576 +193385 Ripor2 MGI:MGI:2444879|Ensembl:ENSMUSG00000036006|Vega:OTTMUSG00000000609 +193403 Gm11392 MGI:MGI:3649835 +193438 Tpi-rs8 MGI:MGI:98806 +193452 Zfp184 MGI:MGI:1922244|Ensembl:ENSMUSG00000006720|Vega:OTTMUSG00000000453 +193453 Gm11292 MGI:MGI:3651660 +193533 Gm4742 MGI:MGI:3645661 +193574 Trav14n-2 MGI:MGI:3645258|IMGT/GENE-DB:TRAV14N-2 +193587 Trav8-2 MGI:MGI:3650859 +193670 Rnf185 MGI:MGI:1922078|Ensembl:ENSMUSG00000020448|Vega:OTTMUSG00000005029 +193736 Zbtb12 MGI:MGI:88133|Ensembl:ENSMUSG00000049823|Vega:OTTMUSG00000037274 +193740 Hspa1a MGI:MGI:96244|Ensembl:ENSMUSG00000091971|Vega:OTTMUSG00000037921 +193742 Abhd16a MGI:MGI:99476|Ensembl:ENSMUSG00000007036|Vega:OTTMUSG00000037924 +193796 Kdm4b MGI:MGI:2442355|Ensembl:ENSMUSG00000024201|Vega:OTTMUSG00000024381 +193813 Mcfd2 MGI:MGI:2183439|Ensembl:ENSMUSG00000024150|Vega:OTTMUSG00000033021 +193838 Eme2 MGI:MGI:1919889|Ensembl:ENSMUSG00000073436|Vega:OTTMUSG00000030476 +194064 LOC194064 - +194126 Mtmr11 MGI:MGI:2652817|Ensembl:ENSMUSG00000045934|Vega:OTTMUSG00000021892 +194189 Gm13136 MGI:MGI:3649290 +194197 Gm12901 MGI:MGI:3650176 +194219 Slfnl1 MGI:MGI:3045330|Ensembl:ENSMUSG00000047518|Vega:OTTMUSG00000008812 +194224 Gm13100 MGI:MGI:3650205 +194225 Gm13103 MGI:MGI:3650203|Ensembl:ENSMUSG00000029451|Vega:OTTMUSG00000010433 +194227 Gm13023 MGI:MGI:3650478|Ensembl:ENSMUSG00000066031|Vega:OTTMUSG00000010009 +194231 Cnksr1 MGI:MGI:2670958|Ensembl:ENSMUSG00000028841|Vega:OTTMUSG00000010566 +194237 Rimkla MGI:MGI:3040686|Ensembl:ENSMUSG00000048899|Vega:OTTMUSG00000009424 +194268 9930104L06Rik MGI:MGI:3041172 +194292 Gm5 MGI:MGI:2684851 +194309 Vps37d MGI:MGI:2159402|Ensembl:ENSMUSG00000043614|Vega:OTTMUSG00000026015 +194352 Trpv5 MGI:MGI:2429764|Ensembl:ENSMUSG00000036899|Vega:OTTMUSG00000051430 +194357 Moxd2 MGI:MGI:2388042|Ensembl:ENSMUSG00000029885|Vega:OTTMUSG00000026863 +194360 Gm4744 MGI:MGI:3643181 +194388 Tet3 MGI:MGI:2446229|Ensembl:ENSMUSG00000034832|Vega:OTTMUSG00000035766 +194401 Mical3 MGI:MGI:2442733|Ensembl:ENSMUSG00000051586|Vega:OTTMUSG00000023537 +194433 Olfr707 MGI:MGI:3030541|Ensembl:ENSMUSG00000069390|Vega:OTTMUSG00000059723 +194588 Obox7 MGI:MGI:3646231|Ensembl:ENSMUSG00000055942|Vega:OTTMUSG00000044570 +194590 Reps2 MGI:MGI:2663511|Ensembl:ENSMUSG00000040855|Vega:OTTMUSG00000019475 +194597 Tmprss11a MGI:MGI:2684853|Ensembl:ENSMUSG00000072845|Vega:OTTMUSG00000035104 +194604 Serpina16 MGI:MGI:2684892|Ensembl:ENSMUSG00000071179|Vega:OTTMUSG00000035407 +194612 Gm9805 MGI:MGI:3642566 +194615 Gm4746 MGI:MGI:3646058 +194642 Slc39a1-ps MGI:MGI:3615375 +194655 Klf11 MGI:MGI:2653368|Ensembl:ENSMUSG00000020653|Vega:OTTMUSG00000027554 +194735 Btg1-ps2 MGI:MGI:3588265|Ensembl:ENSMUSG00000098348 +194738 Rhox11 MGI:MGI:2681831|Ensembl:ENSMUSG00000051038|Vega:OTTMUSG00000017179 +194740 Gm40 MGI:MGI:2684886 +194744 Slc25a43 MGI:MGI:2684854|Ensembl:ENSMUSG00000037636|Vega:OTTMUSG00000017106 +194788 Gm14644 MGI:MGI:3705795 +194854 Gm9 MGI:MGI:2684855|Ensembl:ENSMUSG00000073243|Vega:OTTMUSG00000017120 +194856 Rhox4e MGI:MGI:3613390|Ensembl:ENSMUSG00000071770|Vega:OTTMUSG00000017144 +194905 Rpl9-ps1 MGI:MGI:3649210 +194908 Pld6 MGI:MGI:2687283|Ensembl:ENSMUSG00000043648|Vega:OTTMUSG00000008093 +194952 Jmjd4 MGI:MGI:2144404|Ensembl:ENSMUSG00000036819|Vega:OTTMUSG00000005800 +194960 Rpl27-ps2 MGI:MGI:3649792 +194974 Sun3 MGI:MGI:3041199|Ensembl:ENSMUSG00000040985|Vega:OTTMUSG00000005147 +194985 Gm11658 MGI:MGI:3650797 +195018 Zzef1 MGI:MGI:2444286|Ensembl:ENSMUSG00000055670|Vega:OTTMUSG00000006113 +195040 Tmem199 MGI:MGI:2144113|Ensembl:ENSMUSG00000051232|Vega:OTTMUSG00000000136 +195046 Nlrp1a MGI:MGI:2684861|Ensembl:ENSMUSG00000069830|Vega:OTTMUSG00000006088 +195176 Igh-VX24 MGI:MGI:96492 +195180 Ighv9-1 MGI:MGI:4439911|IMGT/GENE-DB:IGHV9-1 +195208 Dcdc2a MGI:MGI:2652818|Ensembl:ENSMUSG00000035910|Vega:OTTMUSG00000000615 +195209 Zfp469 MGI:MGI:2684868 +195236 Pom121l2 MGI:MGI:2684870|Ensembl:ENSMUSG00000016982|Vega:OTTMUSG00000000466 +195296 Trav4d-4 MGI:MGI:2684872|IMGT/GENE-DB:TRAV4D-4 +195297 Trav16 MGI:MGI:3702130|IMGT/GENE-DB:TRAV16 +195333 Gsc2 MGI:MGI:892006|Ensembl:ENSMUSG00000022738|Vega:OTTMUSG00000023599 +195349 Btnl7-ps MGI:MGI:2388054 +195359 Trim40 MGI:MGI:2684881|Ensembl:ENSMUSG00000073399|Vega:OTTMUSG00000037381 +195434 Utp14b MGI:MGI:2445092|Ensembl:ENSMUSG00000079470|Vega:OTTMUSG00000033117 +195514 Gm12464 MGI:MGI:3650645 +195522 Zfp691 MGI:MGI:3041163|Ensembl:ENSMUSG00000045268|Vega:OTTMUSG00000008832 +195531 Zfp982 MGI:MGI:3701121|Ensembl:ENSMUSG00000078496|Vega:OTTMUSG00000010671 +195555 Pramef6 MGI:MGI:3649940|Ensembl:ENSMUSG00000078512|Vega:OTTMUSG00000010429 +195564 Skint3 MGI:MGI:3045331|Ensembl:ENSMUSG00000070868|Vega:OTTMUSG00000008550 +195576 Gm13229 MGI:MGI:3651933 +195646 Hs3st2 MGI:MGI:1333802|Ensembl:ENSMUSG00000046321|Vega:OTTMUSG00000058095 +195712 4930421P07Rik MGI:MGI:1921025 +195726 Scml1 MGI:MGI:2684893 +195727 Nhs MGI:MGI:2684894|Ensembl:ENSMUSG00000059493|Vega:OTTMUSG00000019479 +195733 Grhl1 MGI:MGI:2182540|Ensembl:ENSMUSG00000020656 +195772 Magea9-ps MGI:MGI:1350986 +196594 Bomd3 MGI:MGI:2178243 +196595 Bomd4 MGI:MGI:2178246 +207128 Rwhs MGI:MGI:1890529 +207133 Bbaa11 MGI:MGI:2178472 +207134 Bbaa12 MGI:MGI:2178473 +207135 Bbaa13 MGI:MGI:2178474 +207136 Bbaa15 MGI:MGI:2178477 +207137 Bbaa16 MGI:MGI:2178478 +207138 Bbaa17 MGI:MGI:2178479 +207139 Bbaa20 MGI:MGI:2178484 +207140 Bbaa23 MGI:MGI:2178491 +207141 Bbaa10 MGI:MGI:2178471 +207142 Bbaa14 MGI:MGI:2178476 +207143 Bbaa18 MGI:MGI:2178480 +207144 Bbaa19 MGI:MGI:2178482 +207145 Bbaa21 MGI:MGI:2178485 +207146 Bbaa22 MGI:MGI:2178489 +207151 Slc22a19 MGI:MGI:2442751|Ensembl:ENSMUSG00000024757|Vega:OTTMUSG00000028385 +207157 Gm9871 MGI:MGI:3647145|Ensembl:ENSMUSG00000052236 +207165 Bptf MGI:MGI:2444008|Ensembl:ENSMUSG00000040481|Vega:OTTMUSG00000003587 +207175 Cetn4 MGI:MGI:2677454|Ensembl:ENSMUSG00000045031|Vega:OTTMUSG00000007345 +207181 Rbms3 MGI:MGI:2444477|Ensembl:ENSMUSG00000039607|Vega:OTTMUSG00000036948 +207182 Ggt7 MGI:MGI:1913385|Ensembl:ENSMUSG00000027603|Vega:OTTMUSG00000016060 +207209 Ccdc154 MGI:MGI:2685163|Ensembl:ENSMUSG00000059562|Vega:OTTMUSG00000043229 +207212 Arhgef17 MGI:MGI:2673002|Ensembl:ENSMUSG00000032875|Vega:OTTMUSG00000059372 +207213 Tdpoz1 MGI:MGI:2449436|Ensembl:ENSMUSG00000094084|Vega:OTTMUSG00000042888 +207214 Larp4 MGI:MGI:2443114|Ensembl:ENSMUSG00000023025 +207215 Fbxo40 MGI:MGI:2443753|Ensembl:ENSMUSG00000047746|Vega:OTTMUSG00000024756 +207216 Rpl7l1-ps1 MGI:MGI:3645602 +207227 Stxbp5l MGI:MGI:2443815|Ensembl:ENSMUSG00000022829|Vega:OTTMUSG00000024758 +207259 Zbtb7c MGI:MGI:2443302|Ensembl:ENSMUSG00000044646 +207278 Fchsd2 MGI:MGI:2448475|Ensembl:ENSMUSG00000030691|Vega:OTTMUSG00000025163 +207304 Hectd1 MGI:MGI:2384768|Ensembl:ENSMUSG00000035247 +207318 Gm4750 MGI:MGI:3647391 +207352 Sec23ip MGI:MGI:2450915|Ensembl:ENSMUSG00000055319|Vega:OTTMUSG00000058755 +207375 Fam120c MGI:MGI:2387687|Ensembl:ENSMUSG00000025262|Vega:OTTMUSG00000019172 +207393 Elfn2 MGI:MGI:3608416|Ensembl:ENSMUSG00000043460 +207425 Wdr11 MGI:MGI:1920230|Ensembl:ENSMUSG00000042055|Vega:OTTMUSG00000029364 +207474 Kctd12b MGI:MGI:2444667|Ensembl:ENSMUSG00000041633|Vega:OTTMUSG00000019380 +207495 Baiap2l2 MGI:MGI:2652819|Ensembl:ENSMUSG00000018126|Vega:OTTMUSG00000036034 +207521 Dtx4 MGI:MGI:2672905|Ensembl:ENSMUSG00000039982 +207565 Camkk2 MGI:MGI:2444812|Ensembl:ENSMUSG00000029471|Vega:OTTMUSG00000054556 +207592 Tbc1d16 MGI:MGI:2652878|Ensembl:ENSMUSG00000039976|Vega:OTTMUSG00000004005 +207596 Thsd4 MGI:MGI:2672033|Ensembl:ENSMUSG00000032289|Vega:OTTMUSG00000024676 +207607 Ccdc40 MGI:MGI:2443893|Ensembl:ENSMUSG00000039963|Vega:OTTMUSG00000004002 +207615 Wdr37 MGI:MGI:1920393|Ensembl:ENSMUSG00000021147|Vega:OTTMUSG00000042174 +207618 Zfp804b MGI:MGI:2685287|Ensembl:ENSMUSG00000092094|Vega:OTTMUSG00000054203 +207667 Skor1 MGI:MGI:2443473|Ensembl:ENSMUSG00000022245|Vega:OTTMUSG00000027399 +207683 Igsf11 MGI:MGI:2388477|Ensembl:ENSMUSG00000022790|Vega:OTTMUSG00000016990 +207686 Cfap69 MGI:MGI:2443778|Ensembl:ENSMUSG00000040473|Vega:OTTMUSG00000025942 +207704 Gtpbp10 MGI:MGI:2385599|Ensembl:ENSMUSG00000040464|Vega:OTTMUSG00000021302 +207728 Pde2a MGI:MGI:2446107|Ensembl:ENSMUSG00000030653|Ensembl:ENSMUSG00000110195|Vega:OTTMUSG00000060398|Vega:OTTMUSG00000060399 +207740 Ubald1 MGI:MGI:1916255|Ensembl:ENSMUSG00000039568|Vega:OTTMUSG00000027574 +207742 Rnf43 MGI:MGI:2442609|Ensembl:ENSMUSG00000034177|Vega:OTTMUSG00000001292 +207777 Tspoap1 MGI:MGI:2450877|Ensembl:ENSMUSG00000034156|Vega:OTTMUSG00000001438 +207781 C2cd2 MGI:MGI:1891883|Ensembl:ENSMUSG00000045975 +207785 Csrnp2 MGI:MGI:2386852|Ensembl:ENSMUSG00000044636 +207792 BC034090 MGI:MGI:2672904|Ensembl:ENSMUSG00000033722|Vega:OTTMUSG00000046207 +207798 Gramd1c MGI:MGI:2443024|Ensembl:ENSMUSG00000036292|Vega:OTTMUSG00000024653 +207806 Usf3 MGI:MGI:2685454|Ensembl:ENSMUSG00000068284|Vega:OTTMUSG00000028658 +207818 Smagp MGI:MGI:2448476|Ensembl:ENSMUSG00000053559 +207819 4930539E08Rik MGI:MGI:1925441|Ensembl:ENSMUSG00000048905|Vega:OTTMUSG00000031642 +207839 Galnt6 MGI:MGI:1891640|Ensembl:ENSMUSG00000037280|Vega:OTTMUSG00000035000 +207854 Fmr1nb MGI:MGI:2672032|Ensembl:ENSMUSG00000062170|Vega:OTTMUSG00000017749 +207911 Mchr1 MGI:MGI:2180756|Ensembl:ENSMUSG00000050164 +207920 Esrp1 MGI:MGI:1917326|Ensembl:ENSMUSG00000040728|Vega:OTTMUSG00000004469 +207921 Fam228b MGI:MGI:2442121|Ensembl:ENSMUSG00000050545 +207932 Urb1 MGI:MGI:2146468|Ensembl:ENSMUSG00000039929|Vega:OTTMUSG00000033776 +207933 Gm13502 MGI:MGI:3649894 +207952 Klhl25 MGI:MGI:2668031|Ensembl:ENSMUSG00000055652|Vega:OTTMUSG00000058435 +207958 Alg11 MGI:MGI:2142632|Ensembl:ENSMUSG00000063362|Vega:OTTMUSG00000020828 +207965 Vcpkmt MGI:MGI:2684917|Ensembl:ENSMUSG00000049882 +208043 Setd1b MGI:MGI:2652820|Ensembl:ENSMUSG00000038384|Vega:OTTMUSG00000017166 +208055 Gm4751 MGI:MGI:3644028 +208076 Pknox2 MGI:MGI:2445415|Ensembl:ENSMUSG00000035934|Vega:OTTMUSG00000040107 +208079 A530053G22Rik MGI:MGI:2443347|Ensembl:ENSMUSG00000046764 +208080 Ubap1l MGI:MGI:2685360|Ensembl:ENSMUSG00000086228|Vega:OTTMUSG00000062626 +208084 Pif1 MGI:MGI:2143057|Ensembl:ENSMUSG00000041064|Vega:OTTMUSG00000034117 +208092 Chmp6 MGI:MGI:3583942|Ensembl:ENSMUSG00000025371|Vega:OTTMUSG00000004028 +208098 Panx3 MGI:MGI:1918881|Ensembl:ENSMUSG00000011118|Vega:OTTMUSG00000027406 +208104 Mlxip MGI:MGI:2141183|Ensembl:ENSMUSG00000038342|Vega:OTTMUSG00000025921 +208111 Zfp976 MGI:MGI:3036263|Ensembl:ENSMUSG00000074158|Ensembl:ENSMUSG00000092335|Vega:OTTMUSG00000035833|Vega:OTTMUSG00000037907 +208117 Aph1b MGI:MGI:3522097|Ensembl:ENSMUSG00000032375|Vega:OTTMUSG00000036114 +208144 Dhx37 MGI:MGI:3028576|Ensembl:ENSMUSG00000029480|Vega:OTTMUSG00000055051 +208146 Yeats2 MGI:MGI:2447762|Ensembl:ENSMUSG00000041215 +208151 Tmem132b MGI:MGI:3609245|Ensembl:ENSMUSG00000070498|Vega:OTTMUSG00000044549 +208154 Btla MGI:MGI:2658978|Ensembl:ENSMUSG00000052013|Vega:OTTMUSG00000014972 +208158 Map6d1 MGI:MGI:3607784|Ensembl:ENSMUSG00000041205 +208164 Fam180a MGI:MGI:3039626|Ensembl:ENSMUSG00000047420|Vega:OTTMUSG00000056109 +208166 Gm609 MGI:MGI:2685455|Ensembl:ENSMUSG00000053182|Vega:OTTMUSG00000014969 +208169 Slc9c1 MGI:MGI:2685456|Ensembl:ENSMUSG00000033210|Vega:OTTMUSG00000034157 +208171 Tmprss7 MGI:MGI:2686594|Ensembl:ENSMUSG00000033177|Vega:OTTMUSG00000036562 +208177 Phldb2 MGI:MGI:2444981|Ensembl:ENSMUSG00000033149|Vega:OTTMUSG00000024715 +208188 Ghsr MGI:MGI:2441906|Ensembl:ENSMUSG00000051136|Vega:OTTMUSG00000051188 +208194 Exog MGI:MGI:2143333|Ensembl:ENSMUSG00000042787|Vega:OTTMUSG00000062992 +208198 Btbd2 MGI:MGI:1933831|Ensembl:ENSMUSG00000003344|Vega:OTTMUSG00000032757 +208211 Alg1 MGI:MGI:2384774|Ensembl:ENSMUSG00000039427|Vega:OTTMUSG00000028464 +208213 Tmem132c MGI:MGI:2443061|Ensembl:ENSMUSG00000034324|Vega:OTTMUSG00000029754 +208228 Mob3a MGI:MGI:3050117|Ensembl:ENSMUSG00000003348 +208256 Akp-ps1 MGI:MGI:87981 +208258 Ankrd33 MGI:MGI:2443398|Ensembl:ENSMUSG00000047034 +208263 Tor1aip1 MGI:MGI:3582693|Ensembl:ENSMUSG00000026466|Vega:OTTMUSG00000021975 +208266 Dot1l MGI:MGI:2143886|Ensembl:ENSMUSG00000061589|Vega:OTTMUSG00000017289 +208285 Cyp4f17 MGI:MGI:3646233|Ensembl:ENSMUSG00000091586 +208292 Zfp871 MGI:MGI:1921793|Ensembl:ENSMUSG00000024298|Vega:OTTMUSG00000036486 +208347 Gm4753 MGI:MGI:3648193 +208366 Rpp40 MGI:MGI:1346084|Ensembl:ENSMUSG00000021418|Vega:OTTMUSG00000037298 +208372 Asb18 MGI:MGI:2655109|Ensembl:ENSMUSG00000067081|Vega:OTTMUSG00000026747 +208424 Gm412 MGI:MGI:2685258 +208426 Iqcj MGI:MGI:3644166|Ensembl:ENSMUSG00000051777|Vega:OTTMUSG00000051449 +208428 Rpl19-ps12 MGI:MGI:3651430 +208431 Shroom4 MGI:MGI:2685570|Ensembl:ENSMUSG00000068270|Vega:OTTMUSG00000016659 +208439 Klhl29 MGI:MGI:2683857|Ensembl:ENSMUSG00000020627 +208440 Dip2c MGI:MGI:1920179|Ensembl:ENSMUSG00000048264|Vega:OTTMUSG00000037982 +208449 Sgms1 MGI:MGI:2444110|Ensembl:ENSMUSG00000040451|Vega:OTTMUSG00000033408 +208501 Ndufaf8 MGI:MGI:1913676|Ensembl:ENSMUSG00000078572|Vega:OTTMUSG00000004101 +208518 Cep78 MGI:MGI:1924386|Ensembl:ENSMUSG00000041491 +208522 Gm4754 MGI:MGI:3645925 +208583 Nek11 MGI:MGI:2442276|Ensembl:ENSMUSG00000035032|Vega:OTTMUSG00000024183 +208595 Mterf1b MGI:MGI:3704243|Ensembl:ENSMUSG00000053178|Vega:OTTMUSG00000042135 +208606 Rsrc2 MGI:MGI:1913489|Ensembl:ENSMUSG00000029422|Vega:OTTMUSG00000043608 +208613 Tmem212 MGI:MGI:2685410|Ensembl:ENSMUSG00000043164|Vega:OTTMUSG00000051191 +208618 Etl4 MGI:MGI:95454|Ensembl:ENSMUSG00000036617|Vega:OTTMUSG00000011450 +208624 Alg3 MGI:MGI:1098592|Ensembl:ENSMUSG00000033809|Vega:OTTMUSG00000025946 +208628 Kntc1 MGI:MGI:2673709|Ensembl:ENSMUSG00000029414|Vega:OTTMUSG00000054741 +208634 Tspan10 MGI:MGI:2384781|Ensembl:ENSMUSG00000039691|Vega:OTTMUSG00000004175 +208638 Slc25a38 MGI:MGI:2384782|Ensembl:ENSMUSG00000032519|Vega:OTTMUSG00000033822 +208643 Eif4g1 MGI:MGI:2384784|Ensembl:ENSMUSG00000045983|Vega:OTTMUSG00000024386 +208647 Creb3l2 MGI:MGI:2442695|Ensembl:ENSMUSG00000038648|Vega:OTTMUSG00000023205 +208650 Cblb MGI:MGI:2146430|Ensembl:ENSMUSG00000022637 +208659 Fam20a MGI:MGI:2388266|Ensembl:ENSMUSG00000020614|Vega:OTTMUSG00000003353 +208665 Akr1d1 MGI:MGI:2384785|Ensembl:ENSMUSG00000038641|Vega:OTTMUSG00000022180 +208666 Diras1 MGI:MGI:2183442|Ensembl:ENSMUSG00000043670|Vega:OTTMUSG00000030296 +208677 Creb3l3 MGI:MGI:2384786|Ensembl:ENSMUSG00000035041|Vega:OTTMUSG00000030302 +208691 Eif5a2 MGI:MGI:1933735|Ensembl:ENSMUSG00000050192|Vega:OTTMUSG00000051221 +208715 Hmgcs1 MGI:MGI:107592|Ensembl:ENSMUSG00000093930 +208718 Dis3l2 MGI:MGI:2442555|Ensembl:ENSMUSG00000053333|Vega:OTTMUSG00000048134 +208727 Hdac4 MGI:MGI:3036234|Ensembl:ENSMUSG00000026313|Vega:OTTMUSG00000048554 +208748 Prrg3 MGI:MGI:2685214|Ensembl:ENSMUSG00000033361|Vega:OTTMUSG00000017819 +208760 Aqp12 MGI:MGI:2664636|Ensembl:ENSMUSG00000045091|Vega:OTTMUSG00000048635 +208768 Sde2 MGI:MGI:2384788|Ensembl:ENSMUSG00000038806|Vega:OTTMUSG00000050456 +208777 Sned1 MGI:MGI:3045960|Ensembl:ENSMUSG00000047793|Vega:OTTMUSG00000036435 +208795 Tmem63a MGI:MGI:2384789|Ensembl:ENSMUSG00000026519|Vega:OTTMUSG00000034843 +208820 Triqk MGI:MGI:3650048|Ensembl:ENSMUSG00000055963|Vega:OTTMUSG00000004461 +208836 Fanci MGI:MGI:2384790|Ensembl:ENSMUSG00000039187|Vega:OTTMUSG00000029069 +208846 Daam1 MGI:MGI:1914596|Ensembl:ENSMUSG00000034574 +208869 Dock3 MGI:MGI:2429763|Ensembl:ENSMUSG00000039716|Vega:OTTMUSG00000036142 +208884 Zdhhc9 MGI:MGI:2444393|Ensembl:ENSMUSG00000036985|Vega:OTTMUSG00000017508 +208890 Slc26a7 MGI:MGI:2384791|Ensembl:ENSMUSG00000040569|Vega:OTTMUSG00000004548 +208898 Unc13c MGI:MGI:2149021|Ensembl:ENSMUSG00000062151|Vega:OTTMUSG00000044794 +208908 Ccdc62 MGI:MGI:2684996|Ensembl:ENSMUSG00000061882|Vega:OTTMUSG00000035341 +208922 Cpeb3 MGI:MGI:2443075|Ensembl:ENSMUSG00000039652|Vega:OTTMUSG00000033003 +208924 A730045E13Rik MGI:MGI:2685430 +208936 Adamts18 MGI:MGI:2442600|Ensembl:ENSMUSG00000053399|Vega:OTTMUSG00000061750 +208941 Gm4755 MGI:MGI:3779434 +208943 Myo5c MGI:MGI:2442485|Ensembl:ENSMUSG00000033590|Vega:OTTMUSG00000062795 +208967 Thnsl1 MGI:MGI:2139347|Ensembl:ENSMUSG00000048550|Vega:OTTMUSG00000011666 +208968 Zfp280c MGI:MGI:2387585|Ensembl:ENSMUSG00000036916|Vega:OTTMUSG00000017553 +208982 Hmgcll1 MGI:MGI:2446108|Ensembl:ENSMUSG00000007908|Vega:OTTMUSG00000027403 +208987 BC025031 MGI:MGI:2661719 +208990 Npb MGI:MGI:2387153|Ensembl:ENSMUSG00000044034|Vega:OTTMUSG00000004082 +208994 Fam83b MGI:MGI:2685362|Ensembl:ENSMUSG00000032358|Vega:OTTMUSG00000044827 +209003 Rbmx2 MGI:MGI:1919414|Ensembl:ENSMUSG00000031107|Vega:OTTMUSG00000017714 +209005 Gm595 MGI:MGI:2685441|Ensembl:ENSMUSG00000079606|Vega:OTTMUSG00000017715 +209011 Sirt7 MGI:MGI:2385849|Ensembl:ENSMUSG00000025138|Vega:OTTMUSG00000004085 +209012 Ulk4 MGI:MGI:1921622|Ensembl:ENSMUSG00000040936|Vega:OTTMUSG00000036158 +209018 Vps8 MGI:MGI:2146407|Ensembl:ENSMUSG00000033653|Vega:OTTMUSG00000027225 +209027 Pycr1 MGI:MGI:2384795|Ensembl:ENSMUSG00000025140|Vega:OTTMUSG00000004087 +209032 Zc3hav1l MGI:MGI:2443387|Ensembl:ENSMUSG00000047749|Vega:OTTMUSG00000026884 +209039 Tns2 MGI:MGI:2387586|Ensembl:ENSMUSG00000037003 +209047 Gipc3 MGI:MGI:2387006|Ensembl:ENSMUSG00000034872|Vega:OTTMUSG00000027857 +209086 Samd9l MGI:MGI:1343184|Ensembl:ENSMUSG00000047735|Vega:OTTMUSG00000029668 +209091 Ccnb3 MGI:MGI:2183443|Ensembl:ENSMUSG00000051592|Vega:OTTMUSG00000016675 +209100 Gm14380 MGI:MGI:3649347 +209131 Snx30 MGI:MGI:2443882|Ensembl:ENSMUSG00000028385|Vega:OTTMUSG00000007408 +209176 Ido2 MGI:MGI:2142489|Ensembl:ENSMUSG00000031549|Vega:OTTMUSG00000029868 +209183 Gm4756 MGI:MGI:3644906 +209186 Acnat2 MGI:MGI:2444345|Ensembl:ENSMUSG00000060317|Vega:OTTMUSG00000006911 +209192 U06147 MGI:MGI:105987 +209195 Clic6 MGI:MGI:2146607|Ensembl:ENSMUSG00000022949|Vega:OTTMUSG00000028529 +209200 Dtx3l MGI:MGI:2656973|Ensembl:ENSMUSG00000049502|Vega:OTTMUSG00000023635 +209212 Osgin2 MGI:MGI:2384798|Ensembl:ENSMUSG00000041153|Vega:OTTMUSG00000004634 +209224 Enox2 MGI:MGI:2384799|Ensembl:ENSMUSG00000031109|Vega:OTTMUSG00000017716 +209225 Zfp710 MGI:MGI:1921747|Ensembl:ENSMUSG00000048897|Vega:OTTMUSG00000058605 +209232 Wfdc5 MGI:MGI:2384800|Ensembl:ENSMUSG00000040154|Vega:OTTMUSG00000001076 +209239 Gan MGI:MGI:1890619|Ensembl:ENSMUSG00000052557|Vega:OTTMUSG00000033779 +209268 Igsf1 MGI:MGI:2147913|Ensembl:ENSMUSG00000031111|Vega:OTTMUSG00000017798 +209281 Gm4757 MGI:MGI:3647440 +209294 Csta1 MGI:MGI:3524930|Ensembl:ENSMUSG00000034362|Vega:OTTMUSG00000026729 +209318 Gps1 MGI:MGI:2384801|Ensembl:ENSMUSG00000025156|Vega:OTTMUSG00000004142 +209324 Gm4758 MGI:MGI:3648404|Ensembl:ENSMUSG00000079595 +209334 Gen1 MGI:MGI:2443149|Ensembl:ENSMUSG00000051235 +209351 Wfdc6a MGI:MGI:2684968|Ensembl:ENSMUSG00000074595|Vega:OTTMUSG00000001095 +209354 Eif2b1 MGI:MGI:2384802|Ensembl:ENSMUSG00000029388|Vega:OTTMUSG00000024473 +209357 Gtf2h3 MGI:MGI:1277143|Ensembl:ENSMUSG00000029387|Vega:OTTMUSG00000024483 +209361 Taf3 MGI:MGI:2388097|Ensembl:ENSMUSG00000025782|Vega:OTTMUSG00000011183 +209378 Itih5 MGI:MGI:1925751|Ensembl:ENSMUSG00000025780|Vega:OTTMUSG00000011192 +209380 Gm4759 MGI:MGI:3647753 +209387 Trim30d MGI:MGI:3035181|Ensembl:ENSMUSG00000057596|Vega:OTTMUSG00000019202 +209416 Gpkow MGI:MGI:1859610|Ensembl:ENSMUSG00000031148|Vega:OTTMUSG00000017806 +209446 Tfe3 MGI:MGI:98511|Ensembl:ENSMUSG00000000134|Vega:OTTMUSG00000017822 +209448 Hoxc10 MGI:MGI:96192|Ensembl:ENSMUSG00000022484|Vega:OTTMUSG00000037394 +209456 Trp53bp2 MGI:MGI:2138319|Ensembl:ENSMUSG00000026510|Vega:OTTMUSG00000027043 +209462 Hace1 MGI:MGI:2446110|Ensembl:ENSMUSG00000038822|Vega:OTTMUSG00000025958 +209478 Tbc1d12 MGI:MGI:2384803|Ensembl:ENSMUSG00000048720 +209488 Hsh2d MGI:MGI:2676364|Ensembl:ENSMUSG00000062007|Vega:OTTMUSG00000062095 +209497 Tmem164 MGI:MGI:2148020|Ensembl:ENSMUSG00000047045|Vega:OTTMUSG00000018828 +209512 Taar2 MGI:MGI:2685071|Ensembl:ENSMUSG00000059763|Vega:OTTMUSG00000019217 +209513 Taar4 MGI:MGI:2685072|Ensembl:ENSMUSG00000069707|Vega:OTTMUSG00000019215 +209517 Taar7b MGI:MGI:3527438|Ensembl:ENSMUSG00000095171|Vega:OTTMUSG00000019225 +209540 Rgag1 MGI:MGI:2685231|Ensembl:ENSMUSG00000085584|Vega:OTTMUSG00000018863 +209541 Gm4760 MGI:MGI:3647548 +209550 Rad51ap2 MGI:MGI:3644580|Ensembl:ENSMUSG00000086022 +209558 Enpp3 MGI:MGI:2143702|Ensembl:ENSMUSG00000019989 +209584 Tyw3 MGI:MGI:2445040|Ensembl:ENSMUSG00000047583|Vega:OTTMUSG00000022728 +209586 Nudcd3 MGI:MGI:2144158|Ensembl:ENSMUSG00000053838|Vega:OTTMUSG00000005106 +209588 Sectm1a MGI:MGI:2384805|Ensembl:ENSMUSG00000025165|Vega:OTTMUSG00000004160 +209589 Gm4761 MGI:MGI:3648855 +209590 Il23r MGI:MGI:2181693|Ensembl:ENSMUSG00000049093|Vega:OTTMUSG00000029859 +209601 Erich3 MGI:MGI:1919095|Ensembl:ENSMUSG00000078161|Vega:OTTMUSG00000037110 +209630 Frmd4a MGI:MGI:1919850|Ensembl:ENSMUSG00000026657|Vega:OTTMUSG00000010755 +209645 Bend7 MGI:MGI:2443100|Ensembl:ENSMUSG00000048186|Vega:OTTMUSG00000010737 +209683 Ttc28 MGI:MGI:2140873|Ensembl:ENSMUSG00000033209|Vega:OTTMUSG00000028650 +209692 Dhtkd1 MGI:MGI:2445096|Ensembl:ENSMUSG00000025815|Vega:OTTMUSG00000010877 +209707 Lcorl MGI:MGI:2651932|Ensembl:ENSMUSG00000015882|Vega:OTTMUSG00000027820 +209737 Kif15 MGI:MGI:1098258|Ensembl:ENSMUSG00000036768|Vega:OTTMUSG00000062832 +209743 AF529169 MGI:MGI:2667167|Ensembl:ENSMUSG00000039313|Vega:OTTMUSG00000045620 +209753 Cyp2c52-ps MGI:MGI:3716994 +209760 Tmc7 MGI:MGI:2443317|Ensembl:ENSMUSG00000042246|Vega:OTTMUSG00000031283 +209773 Dennd2a MGI:MGI:2444961|Ensembl:ENSMUSG00000038456|Vega:OTTMUSG00000022791 +209776 Gpr139 MGI:MGI:2685341|Ensembl:ENSMUSG00000066197|Vega:OTTMUSG00000059099 +209786 Vmn2r-ps88 MGI:MGI:3643761 +209815 Tbc1d25 MGI:MGI:2444862|Ensembl:ENSMUSG00000039201|Vega:OTTMUSG00000018118 +209824 Vmn1r183 MGI:MGI:3033484|Ensembl:ENSMUSG00000066723|Vega:OTTMUSG00000038017 +209837 Slc38a5 MGI:MGI:2148066|Ensembl:ENSMUSG00000031170|Vega:OTTMUSG00000018133 +209966 Pgbd5 MGI:MGI:2429955|Ensembl:ENSMUSG00000050751|Vega:OTTMUSG00000027609 +210004 B3gntl1 MGI:MGI:2441705|Ensembl:ENSMUSG00000046605|Vega:OTTMUSG00000004680 +210009 Mtrr MGI:MGI:1891037|Ensembl:ENSMUSG00000034617 +210027 Slc35f3 MGI:MGI:2444426|Ensembl:ENSMUSG00000057060|Vega:OTTMUSG00000029955 +210029 Metrnl MGI:MGI:2384806|Ensembl:ENSMUSG00000039208|Vega:OTTMUSG00000007591 +210035 Nemp1 MGI:MGI:2446113|Ensembl:ENSMUSG00000040195|Vega:OTTMUSG00000031893 +210044 Adcy2 MGI:MGI:99676|Ensembl:ENSMUSG00000021536 +210045 Nlrp4b MGI:MGI:3056570|Ensembl:ENSMUSG00000034087|Vega:OTTMUSG00000027117 +210094 Iglon5 MGI:MGI:2686277|Ensembl:ENSMUSG00000013367|Vega:OTTMUSG00000016918 +210104 Zfp658 MGI:MGI:2652821|Ensembl:ENSMUSG00000056592|Vega:OTTMUSG00000022472 +210105 Zfp719 MGI:MGI:2444708|Ensembl:ENSMUSG00000030469|Vega:OTTMUSG00000022474 +210106 Papd7 MGI:MGI:2682295|Ensembl:ENSMUSG00000034575|Vega:OTTMUSG00000032573 +210108 D130043K22Rik MGI:MGI:3036268|Ensembl:ENSMUSG00000006711|Vega:OTTMUSG00000000610 +210126 Lpp MGI:MGI:2441849|Ensembl:ENSMUSG00000033306 +210135 Zfp180 MGI:MGI:1923701|Ensembl:ENSMUSG00000057101|Vega:OTTMUSG00000057894 +210145 Irgc1 MGI:MGI:2685948|Ensembl:ENSMUSG00000062028|Vega:OTTMUSG00000058077 +210146 Irgq MGI:MGI:2667176|Ensembl:ENSMUSG00000041037|Vega:OTTMUSG00000058219 +210148 Slc30a6 MGI:MGI:2386741|Ensembl:ENSMUSG00000024069 +210155 Gm4763 MGI:MGI:3643098|Ensembl:ENSMUSG00000058717|Vega:OTTMUSG00000058233 +210162 Zkscan2 MGI:MGI:2444060|Ensembl:ENSMUSG00000030757|Vega:OTTMUSG00000029820 +210172 Zfp526 MGI:MGI:2445181|Ensembl:ENSMUSG00000046541|Vega:OTTMUSG00000058245 +210198 Gprc6a MGI:MGI:2429498|Ensembl:ENSMUSG00000019905 +210274 Shank2 MGI:MGI:2671987|Ensembl:ENSMUSG00000037541|Vega:OTTMUSG00000016451 +210293 Dock10 MGI:MGI:2146320|Ensembl:ENSMUSG00000038608|Vega:OTTMUSG00000047903 +210297 Lrch2 MGI:MGI:2147870|Ensembl:ENSMUSG00000031290|Vega:OTTMUSG00000018961 +210321 BC048679 MGI:MGI:3510776|Ensembl:ENSMUSG00000061877|Vega:OTTMUSG00000033708 +210356 Nckap5 MGI:MGI:2686394|Ensembl:ENSMUSG00000049690|Vega:OTTMUSG00000030251 +210373 A530095I07Rik MGI:MGI:2685376 +210376 Mtmr9 MGI:MGI:2442842|Ensembl:ENSMUSG00000035078 +210417 Thsd7b MGI:MGI:2443925|Ensembl:ENSMUSG00000042581|Vega:OTTMUSG00000026224 +210457 Gm4764 MGI:MGI:3648336 +210463 Slc22a22 MGI:MGI:2446114|Ensembl:ENSMUSG00000022366|Vega:OTTMUSG00000024272 +210465 Vmn2r-ps123 MGI:MGI:3761608 +210503 Zfp677 MGI:MGI:3053207|Ensembl:ENSMUSG00000062743|Vega:OTTMUSG00000034718 +210510 Tdrd6 MGI:MGI:2679727|Ensembl:ENSMUSG00000040140|Vega:OTTMUSG00000028302 +210529 Mettl14 MGI:MGI:2442926|Ensembl:ENSMUSG00000028114|Vega:OTTMUSG00000037048 +210530 P3h2 MGI:MGI:2146663|Ensembl:ENSMUSG00000038168|Vega:OTTMUSG00000034730 +210535 Gm12169 MGI:MGI:3650838|Ensembl:ENSMUSG00000078924|Vega:OTTMUSG00000005497 +210544 Tbc1d31 MGI:MGI:2684931|Ensembl:ENSMUSG00000022364|Vega:OTTMUSG00000034888 +210554 Hus1b MGI:MGI:2671003|Ensembl:ENSMUSG00000076430|Vega:OTTMUSG00000000675 +210562 Gm4766 MGI:MGI:3649016 +210573 Tmem151b MGI:MGI:2685169|Ensembl:ENSMUSG00000096847 +210582 Coq10a MGI:MGI:2684847|Ensembl:ENSMUSG00000039914 +210583 Gm4767 MGI:MGI:3644409|Ensembl:ENSMUSG00000094076|Vega:OTTMUSG00000047160 +210622 Pamr1 MGI:MGI:2445082|Ensembl:ENSMUSG00000027188|Vega:OTTMUSG00000014840 +210673 Prrt3 MGI:MGI:2444810|Ensembl:ENSMUSG00000045009|Vega:OTTMUSG00000056504 +210710 Gab3 MGI:MGI:2387324|Ensembl:ENSMUSG00000032750|Vega:OTTMUSG00000018282 +210711 Mcmbp MGI:MGI:1920977|Ensembl:ENSMUSG00000048170|Vega:OTTMUSG00000029389 +210714 Gm4768 MGI:MGI:3643845 +210719 Mkx MGI:MGI:2687286|Ensembl:ENSMUSG00000061013|Vega:OTTMUSG00000040097 +210741 Kcnk12 MGI:MGI:2684043|Ensembl:ENSMUSG00000050138 +210757 Themis MGI:MGI:2443552|Ensembl:ENSMUSG00000049109|Vega:OTTMUSG00000034168 +210762 Ppp1r36 MGI:MGI:2684916|Ensembl:ENSMUSG00000052221 +210766 Brcc3 MGI:MGI:2389572|Ensembl:ENSMUSG00000031201|Vega:OTTMUSG00000020858 +210789 Tbc1d4 MGI:MGI:2429660|Ensembl:ENSMUSG00000033083|Vega:OTTMUSG00000034685 +210801 Unc5d MGI:MGI:2389364|Ensembl:ENSMUSG00000063626|Vega:OTTMUSG00000061092 +210808 Lacc1 MGI:MGI:2445077|Ensembl:ENSMUSG00000044350|Vega:OTTMUSG00000027801 +210853 Zfp947 MGI:MGI:3646759|Ensembl:ENSMUSG00000063383|Vega:OTTMUSG00000033062 +210876 Vmn2r111 MGI:MGI:3647034|Ensembl:ENSMUSG00000095093|Vega:OTTMUSG00000039899 +210925 Ints9 MGI:MGI:1098533|Ensembl:ENSMUSG00000021975 +210933 Adgrb3 MGI:MGI:2441837|Ensembl:ENSMUSG00000033569|Vega:OTTMUSG00000025352 +210940 4931408C20Rik MGI:MGI:3588222|Ensembl:ENSMUSG00000073722|Vega:OTTMUSG00000039939 +210962 Gm597 MGI:MGI:2685443|Ensembl:ENSMUSG00000048411|Vega:OTTMUSG00000048685 +210973 Kbtbd2 MGI:MGI:2384811|Ensembl:ENSMUSG00000059486|Vega:OTTMUSG00000057740 +210982 Bicral MGI:MGI:2673855|Ensembl:ENSMUSG00000036568 +210992 Lpcat1 MGI:MGI:2384812|Ensembl:ENSMUSG00000021608|Vega:OTTMUSG00000033733 +210998 Fam91a1 MGI:MGI:1277178|Ensembl:ENSMUSG00000037119 +211001 8030423F21Rik MGI:MGI:2443206|Ensembl:ENSMUSG00000052295 +211006 Sepsecs MGI:MGI:1098791|Ensembl:ENSMUSG00000029173|Vega:OTTMUSG00000023343 +211007 Trim41 MGI:MGI:2384814|Ensembl:ENSMUSG00000040365|Vega:OTTMUSG00000005520 +211027 Trav3-4 MGI:MGI:2684925|IMGT/GENE-DB:TRAV3-4 +211039 BC016548 MGI:MGI:2448478|Ensembl:ENSMUSG00000070794 +211064 Alkbh1 MGI:MGI:2384034|Ensembl:ENSMUSG00000079036|Vega:OTTMUSG00000033357 +211134 Lzts1 MGI:MGI:2684762|Ensembl:ENSMUSG00000036306|Vega:OTTMUSG00000044658 +211135 D130040H23Rik MGI:MGI:2444324|Ensembl:ENSMUSG00000079038 +211147 March11 MGI:MGI:3608327|Ensembl:ENSMUSG00000022269|Vega:OTTMUSG00000032749 +211151 Churc1 MGI:MGI:1923684|Ensembl:ENSMUSG00000090258|Vega:OTTMUSG00000033889 +211187 Lrtm2 MGI:MGI:2141485|Ensembl:ENSMUSG00000055003|Vega:OTTMUSG00000023523 +211208 Gm382 MGI:MGI:2685228|Ensembl:ENSMUSG00000062791|Vega:OTTMUSG00000018633 +211223 Vmn2r15 MGI:MGI:3649165|Ensembl:ENSMUSG00000091375|Vega:OTTMUSG00000039865 +211228 Lrrc25 MGI:MGI:2445284|Ensembl:ENSMUSG00000049988|Vega:OTTMUSG00000061449 +211232 Cpne9 MGI:MGI:2443052|Ensembl:ENSMUSG00000030270|Vega:OTTMUSG00000022223 +211253 Mtrf1 MGI:MGI:2384815|Ensembl:ENSMUSG00000022022 +211255 Kbtbd7 MGI:MGI:2685141|Ensembl:ENSMUSG00000043881 +211286 Cln5 MGI:MGI:2442253|Ensembl:ENSMUSG00000022125 +211305 Fbxw13 MGI:MGI:3505590|Ensembl:ENSMUSG00000049314|Vega:OTTMUSG00000027434 +211323 Nrg1 MGI:MGI:96083|Ensembl:ENSMUSG00000062991|Vega:OTTMUSG00000059179 +211329 Ncoa7 MGI:MGI:2444847|Ensembl:ENSMUSG00000039697|Vega:OTTMUSG00000063821 +211331 Ighv1-54 MGI:MGI:3647133|IMGT/GENE-DB:IGHV1-54 +211347 Pank3 MGI:MGI:2387464|Ensembl:ENSMUSG00000018846|Vega:OTTMUSG00000005412 +211378 6720489N17Rik MGI:MGI:2443901|Ensembl:ENSMUSG00000072066|Vega:OTTMUSG00000056316 +211383 Amer3 MGI:MGI:3026939|Ensembl:ENSMUSG00000045174|Vega:OTTMUSG00000049476 +211389 Suox MGI:MGI:2446117|Ensembl:ENSMUSG00000049858 +211401 Mtss1 MGI:MGI:2384818|Ensembl:ENSMUSG00000022353 +211429 Pla2g4b MGI:MGI:2384819|Ensembl:ENSMUSG00000098488|Vega:OTTMUSG00000015287 +211446 Exoc3 MGI:MGI:2443972|Ensembl:ENSMUSG00000034152 +211468 Kcnh8 MGI:MGI:2445160|Ensembl:ENSMUSG00000035580|Vega:OTTMUSG00000044933 +211472 Olfr1373 MGI:MGI:3031207|Ensembl:ENSMUSG00000062204|Vega:OTTMUSG00000005616 +211480 Kcnj14 MGI:MGI:2384820|Ensembl:ENSMUSG00000058743|Vega:OTTMUSG00000059933 +211482 Efhb MGI:MGI:3045296|Ensembl:ENSMUSG00000023931 +211484 Tsga10 MGI:MGI:2685063|Ensembl:ENSMUSG00000060771|Vega:OTTMUSG00000023825 +211488 Ado MGI:MGI:2685083|Ensembl:ENSMUSG00000057134 +211496 4932415M13Rik MGI:MGI:3608328|Ensembl:ENSMUSG00000062036 +211499 Tmem87a MGI:MGI:2441844|Ensembl:ENSMUSG00000033808|Vega:OTTMUSG00000015281 +211535 Ccdc114 MGI:MGI:2446120|Ensembl:ENSMUSG00000040189|Vega:OTTMUSG00000027248 +211548 Nomo1 MGI:MGI:2385850|Ensembl:ENSMUSG00000030835|Vega:OTTMUSG00000043294 +211550 Tifa MGI:MGI:2182965|Ensembl:ENSMUSG00000046688|Vega:OTTMUSG00000036830 +211556 Ap1ar MGI:MGI:2384822|Ensembl:ENSMUSG00000074238|Vega:OTTMUSG00000052811 +211577 Mrgprf MGI:MGI:2384823|Ensembl:ENSMUSG00000031070|Vega:OTTMUSG00000027235 +211578 Mrgprd MGI:MGI:3033142|Ensembl:ENSMUSG00000051207|Vega:OTTMUSG00000059893 +211586 Tfdp2 MGI:MGI:107167|Ensembl:ENSMUSG00000032411|Vega:OTTMUSG00000047569 +211612 Ptchd1 MGI:MGI:2685233|Ensembl:ENSMUSG00000041552|Vega:OTTMUSG00000019362 +211619 Rpl48-ps1 MGI:MGI:3644204 +211623 Plac9a MGI:MGI:2663998|Ensembl:ENSMUSG00000095304|Vega:OTTMUSG00000044550 +211651 Fancd2 MGI:MGI:2448480|Ensembl:ENSMUSG00000034023|Vega:OTTMUSG00000023488 +211652 Wwc1 MGI:MGI:2388637|Ensembl:ENSMUSG00000018849|Vega:OTTMUSG00000005418 +211660 Cspp1 MGI:MGI:2681832|Ensembl:ENSMUSG00000056763|Vega:OTTMUSG00000027401 +211666 Mgst2 MGI:MGI:2448481|Ensembl:ENSMUSG00000074604|Vega:OTTMUSG00000030621 +211673 Arfgef1 MGI:MGI:2442988|Ensembl:ENSMUSG00000067851|Vega:OTTMUSG00000033923 +211702 Gm4772 MGI:MGI:3648584 +211705 Gm4773 MGI:MGI:3648585 +211712 Pcdh9 MGI:MGI:1306801|Ensembl:ENSMUSG00000055421|Vega:OTTMUSG00000050936 +211739 Vstm2a MGI:MGI:2384826|Ensembl:ENSMUSG00000048834|Vega:OTTMUSG00000005182 +211770 Trib1 MGI:MGI:2443397|Ensembl:ENSMUSG00000032501|Vega:OTTMUSG00000028043 +211798 Mfsd9 MGI:MGI:2443548|Ensembl:ENSMUSG00000041945|Vega:OTTMUSG00000022617 +211832 Gm4774 MGI:MGI:3647065 +211895 Smarce1-ps1 MGI:MGI:3037673 +211896 Depdc7 MGI:MGI:2139258|Ensembl:ENSMUSG00000027173|Vega:OTTMUSG00000014963 +211914 Asap2 MGI:MGI:2685438|Ensembl:ENSMUSG00000052632|Vega:OTTMUSG00000037685 +211922 Dennd6a MGI:MGI:2442980|Ensembl:ENSMUSG00000040818|Vega:OTTMUSG00000056602 +211924 Dsg1c MGI:MGI:2664358|Ensembl:ENSMUSG00000034774|Vega:OTTMUSG00000028137 +211936 Ccdc73 MGI:MGI:3606488|Ensembl:ENSMUSG00000045106|Vega:OTTMUSG00000014977 +211945 Plekhh1 MGI:MGI:2144989|Ensembl:ENSMUSG00000060716 +211948 Pde12 MGI:MGI:2443226|Ensembl:ENSMUSG00000043702|Vega:OTTMUSG00000042431 +211949 Spsb4 MGI:MGI:2183445|Ensembl:ENSMUSG00000046997|Vega:OTTMUSG00000028991 +211961 Asxl3 MGI:MGI:2685175|Ensembl:ENSMUSG00000045215|Vega:OTTMUSG00000026799 +211978 Zfyve26 MGI:MGI:1924767|Ensembl:ENSMUSG00000066440 +211986 Tmem18 MGI:MGI:2387176|Ensembl:ENSMUSG00000043061 +212032 Hk3 MGI:MGI:2670962|Ensembl:ENSMUSG00000025877|Vega:OTTMUSG00000032679 +212070 Clrn3 MGI:MGI:2142022|Ensembl:ENSMUSG00000050866|Vega:OTTMUSG00000060274 +212073 Syne3 MGI:MGI:2442408|Ensembl:ENSMUSG00000054150 +212084 Gm4775 MGI:MGI:3647362 +212085 Trim52 MGI:MGI:3045276|Ensembl:ENSMUSG00000022113|Vega:OTTMUSG00000050045 +212090 Tmem60 MGI:MGI:2673965|Ensembl:ENSMUSG00000045435|Vega:OTTMUSG00000029596 +212108 Rln3 MGI:MGI:2158015|Ensembl:ENSMUSG00000045232|Vega:OTTMUSG00000044340 +212111 Inpp5a MGI:MGI:2686961|Ensembl:ENSMUSG00000025477|Vega:OTTMUSG00000024504 +212114 Nhlrc3 MGI:MGI:2444520|Ensembl:ENSMUSG00000042997|Vega:OTTMUSG00000022219 +212123 Dcaf15 MGI:MGI:2684420|Ensembl:ENSMUSG00000037103|Vega:OTTMUSG00000061197 +212124 Cfap46 MGI:MGI:2444387|Ensembl:ENSMUSG00000049571|Vega:OTTMUSG00000031406 +212127 Proser1 MGI:MGI:1919933|Ensembl:ENSMUSG00000049504|Vega:OTTMUSG00000022220 +212139 Cc2d1a MGI:MGI:2384831|Ensembl:ENSMUSG00000036686|Vega:OTTMUSG00000030574 +212153 Ccdc191 MGI:MGI:1922661|Ensembl:ENSMUSG00000022701|Vega:OTTMUSG00000026837 +212163 8030462N17Rik MGI:MGI:2444951|Ensembl:ENSMUSG00000047466 +212167 Gsap MGI:MGI:2442259|Ensembl:ENSMUSG00000039934|Vega:OTTMUSG00000053218 +212168 Zswim4 MGI:MGI:2443726|Ensembl:ENSMUSG00000035671|Vega:OTTMUSG00000061278 +212190 Ubxn10 MGI:MGI:2443123|Ensembl:ENSMUSG00000043621|Vega:OTTMUSG00000010000 +212198 Wdr25 MGI:MGI:3045255|Ensembl:ENSMUSG00000040877 +212225 Stk-ps2 MGI:MGI:3643324|Ensembl:ENSMUSG00000044457 +212241 4930579K21 - +212276 Zfp748 MGI:MGI:1916455|Ensembl:ENSMUSG00000095432|Vega:OTTMUSG00000042798 +212281 Zfp729a MGI:MGI:3036250|Ensembl:ENSMUSG00000021510|Vega:OTTMUSG00000042801 +212285 Arap2 MGI:MGI:2684416|Ensembl:ENSMUSG00000037999|Vega:OTTMUSG00000034699 +212307 Mapre2 MGI:MGI:106271|Ensembl:ENSMUSG00000024277|Vega:OTTMUSG00000028208 +212326 Fam149a MGI:MGI:2387177|Ensembl:ENSMUSG00000070044|Vega:OTTMUSG00000027153 +212377 Mms22l MGI:MGI:2684980|Ensembl:ENSMUSG00000045751|Vega:OTTMUSG00000004797 +212390 Klhl32 MGI:MGI:3612790|Ensembl:ENSMUSG00000040387|Vega:OTTMUSG00000004817 +212391 Lcor MGI:MGI:2443930|Ensembl:ENSMUSG00000025019 +212392 Ccdc110 MGI:MGI:2685018|Ensembl:ENSMUSG00000071104|Vega:OTTMUSG00000036929 +212398 Frat2 MGI:MGI:2673967|Ensembl:ENSMUSG00000047604|Vega:OTTMUSG00000060254 +212399 Gm4777 MGI:MGI:3644085 +212427 A730008H23Rik MGI:MGI:3612871 +212439 AA986860 MGI:MGI:2138143|Ensembl:ENSMUSG00000042510|Vega:OTTMUSG00000049611 +212442 Lactb2 MGI:MGI:2442551|Ensembl:ENSMUSG00000025937|Vega:OTTMUSG00000021599 +212448 9330159F19Rik MGI:MGI:3036239|Ensembl:ENSMUSG00000004360|Vega:OTTMUSG00000063662 +212483 Fam193b MGI:MGI:2385851|Ensembl:ENSMUSG00000021495 +212503 Paox MGI:MGI:1916983|Ensembl:ENSMUSG00000025464|Vega:OTTMUSG00000027287 +212508 Mtg1 MGI:MGI:2685015|Ensembl:ENSMUSG00000039018|Vega:OTTMUSG00000029040 +212514 Spice1 MGI:MGI:1196252|Ensembl:ENSMUSG00000043065|Vega:OTTMUSG00000024208 +212516 Efcab12 MGI:MGI:2681834|Ensembl:ENSMUSG00000030321|Vega:OTTMUSG00000029739 +212517 Cfap44 MGI:MGI:1277238|Ensembl:ENSMUSG00000071550|Vega:OTTMUSG00000027735 +212518 Sprn MGI:MGI:3582583|Ensembl:ENSMUSG00000045733|Vega:OTTMUSG00000029041 +212528 Trmt1 MGI:MGI:1289155|Ensembl:ENSMUSG00000001909|Vega:OTTMUSG00000022183 +212531 Sh3bgrl2 MGI:MGI:1915350|Ensembl:ENSMUSG00000032261|Vega:OTTMUSG00000044944 +212539 Gm266 MGI:MGI:2685112|Ensembl:ENSMUSG00000010529 +212541 Rho MGI:MGI:97914|Ensembl:ENSMUSG00000030324|Vega:OTTMUSG00000056681 +212547 Nepro MGI:MGI:2384836|Ensembl:ENSMUSG00000036208|Vega:OTTMUSG00000028351 +212555 Pqlc2 MGI:MGI:2384837|Ensembl:ENSMUSG00000028744|Vega:OTTMUSG00000009901 +212569 Zfp273 MGI:MGI:3036278|Ensembl:ENSMUSG00000030446|Vega:OTTMUSG00000042807 +212627 Prpsap2 MGI:MGI:2384838|Ensembl:ENSMUSG00000020528|Vega:OTTMUSG00000005840 +212632 Iffo2 MGI:MGI:2140675|Ensembl:ENSMUSG00000041025|Ensembl:ENSMUSG00000094439|Vega:OTTMUSG00000010019|Vega:OTTMUSG00000042401 +212647 Aldh4a1 MGI:MGI:2443883|Ensembl:ENSMUSG00000028737|Vega:OTTMUSG00000010054 +212670 Catsper2 MGI:MGI:2387404|Ensembl:ENSMUSG00000033486|Vega:OTTMUSG00000015263 +212679 Mars2 MGI:MGI:2444136|Ensembl:ENSMUSG00000046994|Vega:OTTMUSG00000046972 +212706 N4bp3 MGI:MGI:2442218|Ensembl:ENSMUSG00000001053|Vega:OTTMUSG00000005606 +212712 Satb2 MGI:MGI:2679336|Ensembl:ENSMUSG00000038331|Vega:OTTMUSG00000023028 +212727 Gm4778 MGI:MGI:3643869 +212728 Tarbp1 MGI:MGI:4936930|Ensembl:ENSMUSG00000090290|Vega:OTTMUSG00000061601 +212733 Bicdl2 MGI:MGI:2388267|Ensembl:ENSMUSG00000043782 +212753 Gm4779 MGI:MGI:3646776 +212772 Arl14ep MGI:MGI:1926020|Ensembl:ENSMUSG00000027122|Vega:OTTMUSG00000015044 +212813 Gm232 MGI:MGI:2685078 +212815 Gm4780 MGI:MGI:3643405 +212862 Chpt1 MGI:MGI:2384841|Ensembl:ENSMUSG00000060002|Vega:OTTMUSG00000031940 +212880 Ddx46 MGI:MGI:1920895|Ensembl:ENSMUSG00000021500 +212892 Rsph4a MGI:MGI:3027894|Ensembl:ENSMUSG00000039552 +212898 Dse MGI:MGI:2443455|Ensembl:ENSMUSG00000039497|Vega:OTTMUSG00000063920 +212919 Kctd7 MGI:MGI:2442265|Ensembl:ENSMUSG00000034110|Vega:OTTMUSG00000026833 +212933 Pm20d1 MGI:MGI:2442939|Ensembl:ENSMUSG00000042251|Vega:OTTMUSG00000021544 +212937 Tifab MGI:MGI:2385852|Ensembl:ENSMUSG00000049625 +212943 Fam46a MGI:MGI:2670964|Ensembl:ENSMUSG00000032265|Vega:OTTMUSG00000045030 +212952 Gm44 MGI:MGI:2684890|Ensembl:ENSMUSG00000091497 +212965 BC024386 MGI:MGI:2669313|Ensembl:ENSMUSG00000109628 +212974 Pgghg MGI:MGI:2444047|Ensembl:ENSMUSG00000062031|Vega:OTTMUSG00000036788 +212980 Slc45a3 MGI:MGI:1922082|Ensembl:ENSMUSG00000026435|Vega:OTTMUSG00000049196 +212986 Scfd2 MGI:MGI:2443446|Ensembl:ENSMUSG00000062110|Vega:OTTMUSG00000028569 +212989 Best2 MGI:MGI:2387588|Ensembl:ENSMUSG00000052819|Vega:OTTMUSG00000061399 +212996 Wbscr17 MGI:MGI:2137594|Ensembl:ENSMUSG00000034040|Vega:OTTMUSG00000030425 +212998 BC016579 MGI:MGI:2384848|Ensembl:ENSMUSG00000033187 +212999 Tnpo2 MGI:MGI:2384849|Ensembl:ENSMUSG00000031691|Vega:OTTMUSG00000061402 +213002 Ifitm6 MGI:MGI:2686976|Ensembl:ENSMUSG00000059108|Vega:OTTMUSG00000060383 +213006 Mfsd4a MGI:MGI:2442786|Ensembl:ENSMUSG00000059149|Vega:OTTMUSG00000024990 +213011 Zfp583 MGI:MGI:2682297|Ensembl:ENSMUSG00000030443|Vega:OTTMUSG00000022344 +213012 Abhd10 MGI:MGI:2442422|Ensembl:ENSMUSG00000033157|Vega:OTTMUSG00000024155 +213019 Pdlim2 MGI:MGI:2384850|Ensembl:ENSMUSG00000022090|Vega:OTTMUSG00000033027 +213027 Evi5l MGI:MGI:2442167|Ensembl:ENSMUSG00000011832|Vega:OTTMUSG00000040168 +213043 Aox2 MGI:MGI:3529596|Ensembl:ENSMUSG00000079554|Vega:OTTMUSG00000047205 +213051 Gm4781 MGI:MGI:3643164 +213053 Slc39a14 MGI:MGI:2384851|Ensembl:ENSMUSG00000022094|Vega:OTTMUSG00000033235 +213054 Gabpb2 MGI:MGI:95612|Ensembl:ENSMUSG00000038766|Vega:OTTMUSG00000022326 +213056 Fam126b MGI:MGI:1098784|Ensembl:ENSMUSG00000038174|Vega:OTTMUSG00000026622 +213068 Tmem71 MGI:MGI:2146049|Ensembl:ENSMUSG00000036944 +213081 Wdr19 MGI:MGI:2443231|Ensembl:ENSMUSG00000037890|Vega:OTTMUSG00000055141 +213084 Cdkl3 MGI:MGI:2388268|Ensembl:ENSMUSG00000020389|Vega:OTTMUSG00000005618 +213109 Phf3 MGI:MGI:2446126|Ensembl:ENSMUSG00000048874|Vega:OTTMUSG00000048797 +213119 Itga10 MGI:MGI:2153482|Ensembl:ENSMUSG00000090210|Vega:OTTMUSG00000029578 +213121 Ankrd35 MGI:MGI:2442590|Ensembl:ENSMUSG00000038354|Vega:OTTMUSG00000030279 +213171 Prss27 MGI:MGI:2450123|Ensembl:ENSMUSG00000050762|Vega:OTTMUSG00000023861 +213208 Il20rb MGI:MGI:2143266|Ensembl:ENSMUSG00000044244|Vega:OTTMUSG00000027484 +213211 Rnf26 MGI:MGI:2388131|Ensembl:ENSMUSG00000053128|Ensembl:ENSMUSG00000111409|Vega:OTTMUSG00000033668|Vega:OTTMUSG00000063181 +213233 Tapbpl MGI:MGI:2384853|Ensembl:ENSMUSG00000038213|Vega:OTTMUSG00000034697 +213234 Zbbx MGI:MGI:2674085|Ensembl:ENSMUSG00000034151|Vega:OTTMUSG00000023487 +213236 Dnd1 MGI:MGI:2447763|Ensembl:ENSMUSG00000044595|Vega:OTTMUSG00000034043 +213248 Wdr49 MGI:MGI:3645287|Ensembl:ENSMUSG00000104301|Vega:OTTMUSG00000051783 +213262 Fstl5 MGI:MGI:2442179|Ensembl:ENSMUSG00000034098|Vega:OTTMUSG00000030459 +213272 Txndc2 MGI:MGI:2389312|Ensembl:ENSMUSG00000050612 +213311 Fbxl21 MGI:MGI:2442921|Ensembl:ENSMUSG00000035509|Vega:OTTMUSG00000027710 +213320 Gm4782 MGI:MGI:3646036 +213326 Scyl2 MGI:MGI:1289172|Ensembl:ENSMUSG00000069539|Vega:OTTMUSG00000037018 +213332 Mfsd4b4 MGI:MGI:3035041 +213350 Gatd1 MGI:MGI:2387178|Ensembl:ENSMUSG00000051007|Vega:OTTMUSG00000016603 +213389 Prdm9 MGI:MGI:2384854|Ensembl:ENSMUSG00000051977 +213391 Rassf4 MGI:MGI:2386853|Ensembl:ENSMUSG00000042129|Vega:OTTMUSG00000056832 +213393 8430408G22Rik MGI:MGI:1918730|Ensembl:ENSMUSG00000048489|Vega:OTTMUSG00000057159 +213402 Armc2 MGI:MGI:1916449|Ensembl:ENSMUSG00000071324|Vega:OTTMUSG00000034286 +213409 Lemd1 MGI:MGI:1922403|Ensembl:ENSMUSG00000079330|Vega:OTTMUSG00000049384 +213417 Klhdc8a MGI:MGI:2442630|Ensembl:ENSMUSG00000042115|Vega:OTTMUSG00000049386 +213422 Rpl28-ps4 MGI:MGI:3645169 +213435 Mylk3 MGI:MGI:2443063|Ensembl:ENSMUSG00000031698|Vega:OTTMUSG00000031870 +213436 Zcchc5 MGI:MGI:2685221|Ensembl:ENSMUSG00000047686|Vega:OTTMUSG00000018368 +213438 A630033H20Rik MGI:MGI:2441814|Ensembl:ENSMUSG00000054293|Vega:OTTMUSG00000018159 +213439 Gpr174 MGI:MGI:2685222|Ensembl:ENSMUSG00000073008|Vega:OTTMUSG00000018153 +213449 Fam46d MGI:MGI:2685223|Ensembl:ENSMUSG00000073007|Vega:OTTMUSG00000018254 +213450 Gm732 MGI:MGI:2685578|Ensembl:ENSMUSG00000073006|Vega:OTTMUSG00000018253 +213452 Dstyk MGI:MGI:1925064|Ensembl:ENSMUSG00000042046|Vega:OTTMUSG00000049388 +213454 Gm378 MGI:MGI:2685224 +213464 Rbbp5 MGI:MGI:1918367|Ensembl:ENSMUSG00000026439|Vega:OTTMUSG00000049391 +213469 Lgi3 MGI:MGI:2182619|Ensembl:ENSMUSG00000033595 +213474 Gm4784 MGI:MGI:3648818 +213480 Trav7-6 MGI:MGI:3702133|IMGT/GENE-DB:TRAV7-6 +213484 Nudt18 MGI:MGI:2385853|Ensembl:ENSMUSG00000045211 +213491 Szrd1 MGI:MGI:1098672|Ensembl:ENSMUSG00000040842|Vega:OTTMUSG00000010147 +213498 Arhgef11 MGI:MGI:2441869|Ensembl:ENSMUSG00000041977|Vega:OTTMUSG00000031939 +213499 Fbxo42 MGI:MGI:1924992|Ensembl:ENSMUSG00000028920|Vega:OTTMUSG00000010145 +213522 Plekhg6 MGI:MGI:2682298|Ensembl:ENSMUSG00000038167|Vega:OTTMUSG00000023204 +213527 Pth2r MGI:MGI:2180917|Ensembl:ENSMUSG00000025946|Vega:OTTMUSG00000022339 +213539 Bag2 MGI:MGI:1891254|Ensembl:ENSMUSG00000042215|Vega:OTTMUSG00000021814 +213541 Ythdf2 MGI:MGI:2444233|Ensembl:ENSMUSG00000040025|Vega:OTTMUSG00000011111 +213544 A330069K06Rik MGI:MGI:2685464 +213550 Dis3l MGI:MGI:2143272|Ensembl:ENSMUSG00000032396|Vega:OTTMUSG00000031812 +213556 Plekhh2 MGI:MGI:2146813|Ensembl:ENSMUSG00000040852 +213570 Ighv1-78 MGI:MGI:4439736 +213573 Cracr2b MGI:MGI:2446129|Ensembl:ENSMUSG00000048200|Vega:OTTMUSG00000036654 +213575 Dync2li1 MGI:MGI:1913996|Ensembl:ENSMUSG00000024253 +213582 Map9 MGI:MGI:2442208|Ensembl:ENSMUSG00000033900|Vega:OTTMUSG00000051755 +213603 Slc44a3 MGI:MGI:2384860|Ensembl:ENSMUSG00000039865|Vega:OTTMUSG00000054990 +213649 Arhgef19 MGI:MGI:1925912|Ensembl:ENSMUSG00000028919|Vega:OTTMUSG00000010201 +213673 9530068E07Rik MGI:MGI:2654705|Ensembl:ENSMUSG00000036275|Vega:OTTMUSG00000005627 +213684 Igkv4-79 MGI:MGI:2685040|IMGT/GENE-DB:IGKV4-79 +213696 Duoxa1 MGI:MGI:2384861|Ensembl:ENSMUSG00000027224|Vega:OTTMUSG00000015567 +213711 Gm4785 MGI:MGI:3646908 +213742 Xist MGI:MGI:98974|Ensembl:ENSMUSG00000086503 +213753 Zfp598 MGI:MGI:2670965|Ensembl:ENSMUSG00000041130 +213760 Prepl MGI:MGI:2441932|Ensembl:ENSMUSG00000024127 +213765 Nutm1 MGI:MGI:2661384|Ensembl:ENSMUSG00000041358|Vega:OTTMUSG00000015142 +213773 Tbl3 MGI:MGI:2384863|Ensembl:ENSMUSG00000040688|Vega:OTTMUSG00000033010 +213781 Gm4786 MGI:MGI:3644879 +213783 Plekhg1 MGI:MGI:2676551|Ensembl:ENSMUSG00000040624|Vega:OTTMUSG00000030941 +213788 Chrm5 MGI:MGI:109248|Ensembl:ENSMUSG00000074939|Vega:OTTMUSG00000015145 +213811 BC002059 MGI:MGI:2384864|Ensembl:ENSMUSG00000060149 +213819 Casd1 MGI:MGI:2384865|Ensembl:ENSMUSG00000015189|Vega:OTTMUSG00000023445 +213827 Arcn1 MGI:MGI:2387591|Ensembl:ENSMUSG00000032096|Vega:OTTMUSG00000030776 +213895 Bms1 MGI:MGI:2446132|Ensembl:ENSMUSG00000030138|Vega:OTTMUSG00000056773 +213945 Col28a1 MGI:MGI:2685312|Ensembl:ENSMUSG00000068794|Vega:OTTMUSG00000022693 +213948 Atg9b MGI:MGI:2685420|Ensembl:ENSMUSG00000038295|Vega:OTTMUSG00000024105 +213956 Fam83f MGI:MGI:2146227|Ensembl:ENSMUSG00000022408 +213980 Fbxw10 MGI:MGI:3052463|Ensembl:ENSMUSG00000090173|Vega:OTTMUSG00000005877 +213988 Tnrc6b MGI:MGI:2443730|Ensembl:ENSMUSG00000047888 +213989 Tmem82 MGI:MGI:2384869|Ensembl:ENSMUSG00000043085|Vega:OTTMUSG00000010342 +213990 Agap3 MGI:MGI:2183446|Ensembl:ENSMUSG00000023353|Vega:OTTMUSG00000053658 +213993 Ccdc186 MGI:MGI:2445022|Ensembl:ENSMUSG00000035173|Vega:OTTMUSG00000028286 +214048 Larp1b MGI:MGI:1914604|Ensembl:ENSMUSG00000025762|Vega:OTTMUSG00000051024 +214058 Megf11 MGI:MGI:1920951|Ensembl:ENSMUSG00000036466|Vega:OTTMUSG00000031743 +214063 Dnajc16 MGI:MGI:2442146|Ensembl:ENSMUSG00000040697|Vega:OTTMUSG00000009933 +214084 Slc18a2 MGI:MGI:106677|Ensembl:ENSMUSG00000025094 +214105 Sox30 MGI:MGI:1341157|Ensembl:ENSMUSG00000040489|Vega:OTTMUSG00000005487 +214106 4933430I17Rik MGI:MGI:3045314|Ensembl:ENSMUSG00000058046|Vega:OTTMUSG00000000237 +214111 Slc24a1 MGI:MGI:2384871|Ensembl:ENSMUSG00000034452|Vega:OTTMUSG00000062614 +214112 Nipal4 MGI:MGI:2444671|Ensembl:ENSMUSG00000020411|Vega:OTTMUSG00000005489 +214133 Tet2 MGI:MGI:2443298|Ensembl:ENSMUSG00000040943|Vega:OTTMUSG00000055135 +214137 Arhgap29 MGI:MGI:2443818|Ensembl:ENSMUSG00000039831|Vega:OTTMUSG00000026603 +214150 Ago3 MGI:MGI:2446634|Ensembl:ENSMUSG00000028842|Vega:OTTMUSG00000009349 +214158 Trim38 MGI:MGI:2684869|Ensembl:ENSMUSG00000064140|Vega:OTTMUSG00000000576 +214162 Kmt2a MGI:MGI:96995|Ensembl:ENSMUSG00000002028|Vega:OTTMUSG00000021055 +214189 Scgn MGI:MGI:2384873|Ensembl:ENSMUSG00000021337|Vega:OTTMUSG00000000592 +214191 Ttc24 MGI:MGI:2443841|Ensembl:ENSMUSG00000051036|Vega:OTTMUSG00000028842 +214230 Pak6 MGI:MGI:2679420|Ensembl:ENSMUSG00000074923|Vega:OTTMUSG00000015368 +214239 A430105I19Rik MGI:MGI:2685199|Ensembl:ENSMUSG00000045838|Vega:OTTMUSG00000015637 +214240 Disp2 MGI:MGI:2388733|Ensembl:ENSMUSG00000040035|Vega:OTTMUSG00000015642 +214253 Etnk2 MGI:MGI:2443760|Ensembl:ENSMUSG00000070644|Vega:OTTMUSG00000026805 +214254 Nudt15 MGI:MGI:2443366|Ensembl:ENSMUSG00000033405 +214290 Zcchc6 MGI:MGI:2387179|Ensembl:ENSMUSG00000035248 +214292 Syna MGI:MGI:2684898|Ensembl:ENSMUSG00000085957|Vega:OTTMUSG00000055748 +214301 Crygn MGI:MGI:2449167|Ensembl:ENSMUSG00000038135|Vega:OTTMUSG00000021290 +214305 Hhipl1 MGI:MGI:1919265|Ensembl:ENSMUSG00000021260 +214308 Gm381 MGI:MGI:2685227 +214321 Gm4787 MGI:MGI:3646380|Ensembl:ENSMUSG00000072974|Vega:OTTMUSG00000035331 +214345 Lrrc1 MGI:MGI:2442313|Ensembl:ENSMUSG00000032352|Vega:OTTMUSG00000044852 +214359 Tmem51 MGI:MGI:2384874|Ensembl:ENSMUSG00000040616|Vega:OTTMUSG00000010186 +214384 Myocd MGI:MGI:2137495|Ensembl:ENSMUSG00000020542|Vega:OTTMUSG00000005903 +214394 A530010F05Rik MGI:MGI:2685406 +214403 Gm4788 MGI:MGI:3646434|Ensembl:ENSMUSG00000070594|Vega:OTTMUSG00000050044 +214424 Parp16 MGI:MGI:2446133|Ensembl:ENSMUSG00000032392|Vega:OTTMUSG00000062621 +214425 Cilp MGI:MGI:2444507|Ensembl:ENSMUSG00000042254|Vega:OTTMUSG00000016695 +214444 Cdk5rap2 MGI:MGI:2384875|Ensembl:ENSMUSG00000039298|Vega:OTTMUSG00000000307 +214450 Gm4789 MGI:MGI:3648623 +214459 Fnbp1l MGI:MGI:1925642|Ensembl:ENSMUSG00000039735|Vega:OTTMUSG00000034289 +214469 Fam168b MGI:MGI:2448487|Ensembl:ENSMUSG00000037503|Vega:OTTMUSG00000021855 +214489 BC003965 MGI:MGI:2670966|Ensembl:ENSMUSG00000067722 +214498 Cdc73 MGI:MGI:2384876|Ensembl:ENSMUSG00000026361|Vega:OTTMUSG00000030974 +214505 Gnptg MGI:MGI:2147006|Ensembl:ENSMUSG00000035521 +214523 Tmprss4 MGI:MGI:2384877|Ensembl:ENSMUSG00000032091|Vega:OTTMUSG00000036044 +214531 Tmprss13 MGI:MGI:2682935|Ensembl:ENSMUSG00000037129|Vega:OTTMUSG00000024620 +214547 She MGI:MGI:1099462|Ensembl:ENSMUSG00000046280|Vega:OTTMUSG00000034177 +214552 Cep164 MGI:MGI:2384878|Ensembl:ENSMUSG00000043987|Vega:OTTMUSG00000031836 +214568 Gm136 MGI:MGI:2684982|Ensembl:ENSMUSG00000071015|Vega:OTTMUSG00000006462 +214572 Prmt7 MGI:MGI:2384879|Ensembl:ENSMUSG00000060098|Vega:OTTMUSG00000020645 +214575 Tdrd5 MGI:MGI:2684949|Ensembl:ENSMUSG00000060985|Vega:OTTMUSG00000026427 +214579 Aldh5a1 MGI:MGI:2441982|Ensembl:ENSMUSG00000035936|Vega:OTTMUSG00000000603 +214580 Pstk MGI:MGI:2685945|Ensembl:ENSMUSG00000063179|Vega:OTTMUSG00000023369 +214585 Spg11 MGI:MGI:2444989|Ensembl:ENSMUSG00000033396|Vega:OTTMUSG00000015533 +214593 Duox2 MGI:MGI:3036280|Ensembl:ENSMUSG00000068452|Vega:OTTMUSG00000015565 +214597 Sidt2 MGI:MGI:2446134|Ensembl:ENSMUSG00000034908|Vega:OTTMUSG00000028905 +214601 Slc10a3 MGI:MGI:95048|Ensembl:ENSMUSG00000032806|Vega:OTTMUSG00000017664 +214616 Spata5l1 MGI:MGI:3036261 +214627 Papd5 MGI:MGI:1917820|Ensembl:ENSMUSG00000036779|Vega:OTTMUSG00000031334 +214639 4930486L24Rik MGI:MGI:1922258|Ensembl:ENSMUSG00000050345 +214642 Cped1 MGI:MGI:2444814|Ensembl:ENSMUSG00000062980|Vega:OTTMUSG00000022850 +214663 Slc25a29 MGI:MGI:2444911|Ensembl:ENSMUSG00000021265|Vega:OTTMUSG00000027570 +214669 L3mbtl2 MGI:MGI:2443584|Ensembl:ENSMUSG00000022394|Vega:OTTMUSG00000038071 +214685 Chadl MGI:MGI:3036284|Ensembl:ENSMUSG00000063765|Vega:OTTMUSG00000038074 +214704 Iqub MGI:MGI:3041159|Ensembl:ENSMUSG00000046192|Vega:OTTMUSG00000026862 +214742 Rcor3 MGI:MGI:2441920|Ensembl:ENSMUSG00000037395|Vega:OTTMUSG00000050904 +214763 Mb21d1 MGI:MGI:2442261|Ensembl:ENSMUSG00000032344|Vega:OTTMUSG00000019697 +214764 Edrf1 MGI:MGI:1919831|Ensembl:ENSMUSG00000039990|Vega:OTTMUSG00000029120 +214766 Mmp21 MGI:MGI:2664387|Ensembl:ENSMUSG00000030981|Vega:OTTMUSG00000027351 +214779 Zfp879 MGI:MGI:3053099|Ensembl:ENSMUSG00000044296|Vega:OTTMUSG00000007896 +214791 Sertad4 MGI:MGI:2443496|Ensembl:ENSMUSG00000016262|Vega:OTTMUSG00000027020 +214804 Syde2 MGI:MGI:3036264|Ensembl:ENSMUSG00000036863|Vega:OTTMUSG00000055198 +214812 Zfp609 MGI:MGI:2674092|Ensembl:ENSMUSG00000040524|Vega:OTTMUSG00000034279 +214854 Neurl3 MGI:MGI:2429944|Ensembl:ENSMUSG00000047180|Vega:OTTMUSG00000045459 +214855 Arid5a MGI:MGI:2443039|Ensembl:ENSMUSG00000037447|Vega:OTTMUSG00000021515 +214895 Lman2l MGI:MGI:2443010|Ensembl:ENSMUSG00000001143|Vega:OTTMUSG00000021558 +214897 Csnk1g1 MGI:MGI:2660884|Ensembl:ENSMUSG00000032384|Vega:OTTMUSG00000029794 +214899 Kdm5a MGI:MGI:2136980|Ensembl:ENSMUSG00000030180|Vega:OTTMUSG00000023926 +214901 Chtf18 MGI:MGI:2384887|Ensembl:ENSMUSG00000019214|Vega:OTTMUSG00000035879 +214917 Fam173a MGI:MGI:2384888|Ensembl:ENSMUSG00000057411 +214922 Slc39a2 MGI:MGI:2684326|Ensembl:ENSMUSG00000072572|Vega:OTTMUSG00000034666 +214931 Fbxl16 MGI:MGI:2448488|Ensembl:ENSMUSG00000025738 +214932 Hdhd5 MGI:MGI:2136976|Ensembl:ENSMUSG00000058979|Vega:OTTMUSG00000022665 +214944 Mob3b MGI:MGI:2664539|Ensembl:ENSMUSG00000073910|Vega:OTTMUSG00000006482 +214951 Rhbdl1 MGI:MGI:2384891|Ensembl:ENSMUSG00000025735|Vega:OTTMUSG00000044813 +214952 Rhot2 MGI:MGI:2384892|Ensembl:ENSMUSG00000025733|Vega:OTTMUSG00000042160 +214968 Sema6d MGI:MGI:2387661|Ensembl:ENSMUSG00000027200|Vega:OTTMUSG00000015256 +214973 Gm11349 MGI:MGI:3652298 +214987 Chtf8 MGI:MGI:2443370|Ensembl:ENSMUSG00000046691|Vega:OTTMUSG00000042130 +215001 Wfikkn1 MGI:MGI:2670967|Ensembl:ENSMUSG00000071192|Vega:OTTMUSG00000042048 +215008 Vezt MGI:MGI:2143698|Ensembl:ENSMUSG00000036099|Vega:OTTMUSG00000030972 +215015 Fam20b MGI:MGI:2443990|Ensembl:ENSMUSG00000033557|Vega:OTTMUSG00000029656 +215028 Prl3d2 MGI:MGI:2660935|Ensembl:ENSMUSG00000062737|Vega:OTTMUSG00000000630 +215029 Prl3d3 MGI:MGI:2660938|Ensembl:ENSMUSG00000062201|Vega:OTTMUSG00000000631 +215031 Vgll2 MGI:MGI:2447460|Ensembl:ENSMUSG00000049641 +215051 Bud13 MGI:MGI:2443443|Ensembl:ENSMUSG00000032077|Vega:OTTMUSG00000028706 +215061 Trim50 MGI:MGI:2664992|Ensembl:ENSMUSG00000053388|Vega:OTTMUSG00000036751 +215085 Slc35f1 MGI:MGI:2139810|Ensembl:ENSMUSG00000038602|Vega:OTTMUSG00000023982 +215090 Maneal MGI:MGI:2684896|Ensembl:ENSMUSG00000042763|Vega:OTTMUSG00000009200 +215095 Astl MGI:MGI:3046414|Ensembl:ENSMUSG00000050468|Vega:OTTMUSG00000016024 +215113 Slc43a2 MGI:MGI:2442746|Ensembl:ENSMUSG00000038178|Vega:OTTMUSG00000006213 +215114 Hip1 MGI:MGI:1099804|Ensembl:ENSMUSG00000039959|Vega:OTTMUSG00000055920 +215160 Rhbdd2 MGI:MGI:1915612|Ensembl:ENSMUSG00000039917|Vega:OTTMUSG00000024289 +215193 Diexf MGI:MGI:2138080|Ensembl:ENSMUSG00000016181|Vega:OTTMUSG00000050855 +215194 Kri1 MGI:MGI:2384899|Ensembl:ENSMUSG00000035047|Vega:OTTMUSG00000044970 +215201 Trmt2b MGI:MGI:2442530|Ensembl:ENSMUSG00000067369|Vega:OTTMUSG00000019176 +215208 Gm4790 MGI:MGI:3646468 +215210 Tmem120a MGI:MGI:2686991|Ensembl:ENSMUSG00000039886|Vega:OTTMUSG00000029604 +215243 Traf3ip3 MGI:MGI:2441706|Ensembl:ENSMUSG00000037318|Vega:OTTMUSG00000027078 +215253 Gm13410 MGI:MGI:3650681 +215257 Il1f9 MGI:MGI:2449929|Ensembl:ENSMUSG00000044103|Vega:OTTMUSG00000011955 +215274 Il1f10 MGI:MGI:2652548|Ensembl:ENSMUSG00000046845|Vega:OTTMUSG00000011964 +215280 Wipf1 MGI:MGI:2178801|Ensembl:ENSMUSG00000075284|Vega:OTTMUSG00000013425 +215303 Camk1g MGI:MGI:2388073|Ensembl:ENSMUSG00000016179|Vega:OTTMUSG00000035816 +215332 Slc36a3 MGI:MGI:2665001|Ensembl:ENSMUSG00000049491|Vega:OTTMUSG00000005688 +215335 Slc36a1 MGI:MGI:2445299|Ensembl:ENSMUSG00000020261|Vega:OTTMUSG00000005687 +215351 Senp6 MGI:MGI:1922075|Ensembl:ENSMUSG00000034252|Vega:OTTMUSG00000042004 +215378 Brinp3 MGI:MGI:2443035|Ensembl:ENSMUSG00000035131|Vega:OTTMUSG00000024055 +215384 Fcgbp MGI:MGI:2444336|Ensembl:ENSMUSG00000047730|Vega:OTTMUSG00000032918 +215387 Ncaph MGI:MGI:2444777|Ensembl:ENSMUSG00000034906|Vega:OTTMUSG00000016017 +215418 Csrnp1 MGI:MGI:2387989|Ensembl:ENSMUSG00000032515|Vega:OTTMUSG00000062306 +215436 Slc35e3 MGI:MGI:2448489|Ensembl:ENSMUSG00000060181 +215445 Rab11fip3 MGI:MGI:2444431|Ensembl:ENSMUSG00000037098|Vega:OTTMUSG00000026527 +215446 Entpd3 MGI:MGI:1321386|Ensembl:ENSMUSG00000041608|Vega:OTTMUSG00000025405 +215449 Rap1b MGI:MGI:894315|Ensembl:ENSMUSG00000052681 +215456 Gpat2 MGI:MGI:2684962|Ensembl:ENSMUSG00000046338|Vega:OTTMUSG00000016022 +215458 LOC215458 - +215467 Gm4791 MGI:MGI:3779436|Ensembl:ENSMUSG00000094893|Vega:OTTMUSG00000063145 +215472 Gm4792 MGI:MGI:3648918|Ensembl:ENSMUSG00000053420|Vega:OTTMUSG00000042487 +215474 Sec22c MGI:MGI:2447871|Ensembl:ENSMUSG00000061536|Vega:OTTMUSG00000027438 +215476 Prr14l MGI:MGI:2443658|Ensembl:ENSMUSG00000054280|Vega:OTTMUSG00000039742 +215493 A3galt2 MGI:MGI:2685279|Ensembl:ENSMUSG00000028794|Vega:OTTMUSG00000009545 +215494 Pomgnt2 MGI:MGI:2143424|Ensembl:ENSMUSG00000066235|Vega:OTTMUSG00000062705 +215512 Fam117a MGI:MGI:2144564|Ensembl:ENSMUSG00000038893|Vega:OTTMUSG00000001662 +215615 Rnpep MGI:MGI:2384902|Ensembl:ENSMUSG00000041926|Vega:OTTMUSG00000021833 +215627 Zbtb8b MGI:MGI:2387181|Ensembl:ENSMUSG00000048485|Vega:OTTMUSG00000009660 +215632 Psd4 MGI:MGI:2674093|Ensembl:ENSMUSG00000026979|Vega:OTTMUSG00000011956 +215641 Mageb18 MGI:MGI:3045344|Ensembl:ENSMUSG00000067649|Vega:OTTMUSG00000017992 +215653 Rassf2 MGI:MGI:2442060|Ensembl:ENSMUSG00000027339|Vega:OTTMUSG00000016204 +215654 Cdh12 MGI:MGI:109503|Ensembl:ENSMUSG00000040452|Vega:OTTMUSG00000025013 +215690 Nav1 MGI:MGI:2183683|Ensembl:ENSMUSG00000009418|Vega:OTTMUSG00000049802 +215693 Zmat1 MGI:MGI:2442284|Ensembl:ENSMUSG00000052676|Vega:OTTMUSG00000018759 +215705 Arrdc1 MGI:MGI:2446136|Ensembl:ENSMUSG00000026972|Vega:OTTMUSG00000012297 +215707 Ccdc92 MGI:MGI:106485|Ensembl:ENSMUSG00000037979|Vega:OTTMUSG00000024484 +215708 Miga1 MGI:MGI:1924567|Ensembl:ENSMUSG00000054942|Vega:OTTMUSG00000053787 +215714 Gm4793 MGI:MGI:3646955 +215723 Mfsd6l MGI:MGI:2384904|Ensembl:ENSMUSG00000048329|Vega:OTTMUSG00000005946 +215728 9230019H11Rik MGI:MGI:3588256|Ensembl:ENSMUSG00000071434 +215748 Cnksr3 MGI:MGI:2674130|Ensembl:ENSMUSG00000015202|Vega:OTTMUSG00000023573 +215751 Ginm1 MGI:MGI:2384905|Ensembl:ENSMUSG00000040006|Vega:OTTMUSG00000033593 +215772 Adgb MGI:MGI:3605549|Ensembl:ENSMUSG00000050994|Vega:OTTMUSG00000023572 +215789 Phactr2 MGI:MGI:2446138|Ensembl:ENSMUSG00000062866|Vega:OTTMUSG00000020940 +215798 Adgrg6 MGI:MGI:1916151|Ensembl:ENSMUSG00000039116|Vega:OTTMUSG00000059618 +215814 Ccdc28a MGI:MGI:2443508|Ensembl:ENSMUSG00000059554|Vega:OTTMUSG00000036976 +215819 Nhsl1 MGI:MGI:106390|Ensembl:ENSMUSG00000039835|Vega:OTTMUSG00000034982 +215821 Arfgef3 MGI:MGI:106387|Ensembl:ENSMUSG00000019852|Vega:OTTMUSG00000063675 +215854 Taar5 MGI:MGI:2685073|Ensembl:ENSMUSG00000069706|Vega:OTTMUSG00000019210 +215855 Taar6 MGI:MGI:2685074|Ensembl:ENSMUSG00000045111|Vega:OTTMUSG00000019218 +215856 Taar7a MGI:MGI:2685075|Ensembl:ENSMUSG00000095647|Vega:OTTMUSG00000019223 +215859 Taar8a MGI:MGI:2685076|Ensembl:ENSMUSG00000096442|Vega:OTTMUSG00000019214 +215866 Gm29673 MGI:MGI:5588832 +215890 Clvs2 MGI:MGI:2443223|Ensembl:ENSMUSG00000019785|Vega:OTTMUSG00000028009 +215895 Sult3a2 MGI:MGI:3645972|Ensembl:ENSMUSG00000090298 +215900 Fam26f MGI:MGI:2443082|Ensembl:ENSMUSG00000046031|Vega:OTTMUSG00000063922 +215919 Rfpl4b MGI:MGI:2684908|Ensembl:ENSMUSG00000094311|Vega:OTTMUSG00000048988 +215928 Mfsd4b5 MGI:MGI:2446139|Ensembl:ENSMUSG00000038528|Vega:OTTMUSG00000036498 +215929 Mfsd4b1 MGI:MGI:2143575|Ensembl:ENSMUSG00000038522|Vega:OTTMUSG00000042237 +215951 Afg1l MGI:MGI:2148801|Ensembl:ENSMUSG00000038302|Vega:OTTMUSG00000019465 +215974 Gm4795 MGI:MGI:3646519 +215999 Mcu MGI:MGI:3026965|Ensembl:ENSMUSG00000009647|Vega:OTTMUSG00000034290 +216001 Micu1 MGI:MGI:2384909|Ensembl:ENSMUSG00000020111|Vega:OTTMUSG00000036457 +216011 Lrrc20 MGI:MGI:2387182|Ensembl:ENSMUSG00000037151 +216019 Hkdc1 MGI:MGI:2384910|Ensembl:ENSMUSG00000020080|Vega:OTTMUSG00000024651 +216021 Stox1 MGI:MGI:2684909|Ensembl:ENSMUSG00000036923|Vega:OTTMUSG00000032815 +216028 Lrrtm3 MGI:MGI:2389177|Ensembl:ENSMUSG00000042846|Vega:OTTMUSG00000023795 +216033 Ctnna3 MGI:MGI:2661445|Ensembl:ENSMUSG00000060843|Vega:OTTMUSG00000023790 +216036 Gm4796 MGI:MGI:3645895 +216049 Zfp365 MGI:MGI:2143676|Ensembl:ENSMUSG00000037855|Vega:OTTMUSG00000027948 +216080 Ube2d1 MGI:MGI:2384911|Ensembl:ENSMUSG00000019927|Vega:OTTMUSG00000031044 +216081 Gm4797 MGI:MGI:3644095 +216082 Gm4798 MGI:MGI:3644096 +216119 Ybey MGI:MGI:2656825|Ensembl:ENSMUSG00000033126 +216131 Trappc10 MGI:MGI:1336209|Ensembl:ENSMUSG00000000374 +216134 Pdxk MGI:MGI:1351869|Ensembl:ENSMUSG00000032788|Vega:OTTMUSG00000020292 +216136 Ilvbl MGI:MGI:1351911|Ensembl:ENSMUSG00000032763 +216144 Vmn2r81 MGI:MGI:2684056|Ensembl:ENSMUSG00000055515|Vega:OTTMUSG00000032820 +216148 Shc2 MGI:MGI:106180|Ensembl:ENSMUSG00000020312 +216150 Cdc34 MGI:MGI:102657|Ensembl:ENSMUSG00000020307 +216151 Polrmt MGI:MGI:1915843|Ensembl:ENSMUSG00000020329|Vega:OTTMUSG00000027870 +216152 Plppr3 MGI:MGI:2388640|Ensembl:ENSMUSG00000035835|Vega:OTTMUSG00000035446 +216154 Med16 MGI:MGI:2158394|Ensembl:ENSMUSG00000013833|Vega:OTTMUSG00000035229 +216156 Wdr18 MGI:MGI:2158400|Ensembl:ENSMUSG00000035754 +216157 Tmem259 MGI:MGI:2177957|Ensembl:ENSMUSG00000013858|Vega:OTTMUSG00000019134 +216161 Sbno2 MGI:MGI:2448490|Ensembl:ENSMUSG00000035673 +216166 Plk5 MGI:MGI:3026984|Ensembl:ENSMUSG00000035486|Vega:OTTMUSG00000019121 +216169 Abhd17a MGI:MGI:106388|Ensembl:ENSMUSG00000003346|Vega:OTTMUSG00000047019 +216177 AU041133 MGI:MGI:2143755|Ensembl:ENSMUSG00000078435|Vega:OTTMUSG00000055597 +216185 Gm4799 MGI:MGI:3648850 +216188 Aldh1l2 MGI:MGI:2444680|Ensembl:ENSMUSG00000020256|Vega:OTTMUSG00000024804 +216190 Appl2 MGI:MGI:2384914|Ensembl:ENSMUSG00000020263|Vega:OTTMUSG00000027828 +216197 Ckap4 MGI:MGI:2444926|Ensembl:ENSMUSG00000046841|Vega:OTTMUSG00000063492 +216198 Tcp11l2 MGI:MGI:2444679|Ensembl:ENSMUSG00000020034|Vega:OTTMUSG00000032574 +216225 Slc5a8 MGI:MGI:2384916|Ensembl:ENSMUSG00000020062 +216227 Slc17a8 MGI:MGI:3039629|Ensembl:ENSMUSG00000019935|Vega:OTTMUSG00000024564 +216229 Gm4800 MGI:MGI:3646193 +216233 Socs2 MGI:MGI:1201787|Ensembl:ENSMUSG00000020027|Vega:OTTMUSG00000028424 +216238 Eea1 MGI:MGI:2442192|Ensembl:ENSMUSG00000036499 +216274 Cep290 MGI:MGI:2384917|Ensembl:ENSMUSG00000019971 +216285 Alx1 MGI:MGI:104621|Ensembl:ENSMUSG00000036602|Vega:OTTMUSG00000036202 +216292 Mettl25 MGI:MGI:3041259|Ensembl:ENSMUSG00000036009|Vega:OTTMUSG00000040134 +216343 Tph2 MGI:MGI:2651811|Ensembl:ENSMUSG00000006764|Vega:OTTMUSG00000020904 +216344 Rab21 MGI:MGI:894308|Ensembl:ENSMUSG00000020132 +216345 Zfc3h1 MGI:MGI:2446143|Ensembl:ENSMUSG00000034163|Vega:OTTMUSG00000033505 +216350 Tspan8 MGI:MGI:2384918|Ensembl:ENSMUSG00000034127 +216363 Rab3ip MGI:MGI:105933|Ensembl:ENSMUSG00000064181 +216377 Gm38403 MGI:MGI:5621288|Ensembl:ENSMUSG00000112854 +216393 D930020B18Rik MGI:MGI:2442001|Ensembl:ENSMUSG00000047642|Vega:OTTMUSG00000031079 +216394 Gm4801 MGI:MGI:3648715 +216395 Tmem5 MGI:MGI:2384919|Ensembl:ENSMUSG00000034620|Vega:OTTMUSG00000027721 +216438 March9 MGI:MGI:2446144|Ensembl:ENSMUSG00000040502|Vega:OTTMUSG00000016665 +216439 Agap2 MGI:MGI:3580016|Ensembl:ENSMUSG00000025422 +216440 Os9 MGI:MGI:1924301|Ensembl:ENSMUSG00000040462 +216441 Slc26a10 MGI:MGI:2143920|Ensembl:ENSMUSG00000040441 +216443 Mars MGI:MGI:1345633|Ensembl:ENSMUSG00000040354|Vega:OTTMUSG00000032541 +216445 Arhgap9 MGI:MGI:2143764|Ensembl:ENSMUSG00000040345 +216453 Rdh19 MGI:MGI:2678390|Ensembl:ENSMUSG00000054052|Vega:OTTMUSG00000027664 +216454 Rdh16f2 MGI:MGI:3583955|Ensembl:ENSMUSG00000074639|Vega:OTTMUSG00000027656 +216456 Gls2 MGI:MGI:2143539|Ensembl:ENSMUSG00000044005|Vega:OTTMUSG00000033507 +216459 Myl6b MGI:MGI:1917789|Ensembl:ENSMUSG00000039824 +216505 Pik3ip1 MGI:MGI:1917016|Ensembl:ENSMUSG00000034614|Vega:OTTMUSG00000000761 +216516 Ccdc157 MGI:MGI:3041210|Ensembl:ENSMUSG00000051427|Vega:OTTMUSG00000005053 +216527 Ccm2 MGI:MGI:2384924|Ensembl:ENSMUSG00000000378|Vega:OTTMUSG00000005120 +216543 Cep68 MGI:MGI:2667663|Ensembl:ENSMUSG00000044066|Vega:OTTMUSG00000005225 +216544 Rpl12-ps2 MGI:MGI:3649989 +216549 Aftph MGI:MGI:1923012|Ensembl:ENSMUSG00000049659|Vega:OTTMUSG00000005232 +216551 Lgalsl MGI:MGI:1916114|Ensembl:ENSMUSG00000042363|Vega:OTTMUSG00000005233 +216558 Ugp2 MGI:MGI:2183447|Ensembl:ENSMUSG00000001891|Vega:OTTMUSG00000005248 +216560 Wdpcp MGI:MGI:2144467|Ensembl:ENSMUSG00000020319|Vega:OTTMUSG00000005251 +216565 Ehbp1 MGI:MGI:2667252|Ensembl:ENSMUSG00000042302|Vega:OTTMUSG00000005255 +216578 Papolg MGI:MGI:2442119|Ensembl:ENSMUSG00000020273|Vega:OTTMUSG00000005284 +216613 Ccdc85a MGI:MGI:2445069|Ensembl:ENSMUSG00000032878|Vega:OTTMUSG00000005313 +216616 Efemp1 MGI:MGI:1339998|Ensembl:ENSMUSG00000020467|Vega:OTTMUSG00000005315 +216618 Cfap36 MGI:MGI:1913994|Ensembl:ENSMUSG00000020462|Vega:OTTMUSG00000005323 +216622 4931440F15Rik MGI:MGI:2441689|Ensembl:ENSMUSG00000078157|Vega:OTTMUSG00000005337 +216635 Hbq1a MGI:MGI:2685722|Ensembl:ENSMUSG00000020295|Vega:OTTMUSG00000005374 +216643 Gabrp MGI:MGI:2387597|Ensembl:ENSMUSG00000020159|Vega:OTTMUSG00000006342 +216644 D130052B06Rik MGI:MGI:2685092 +216705 Clint1 MGI:MGI:2144243|Ensembl:ENSMUSG00000006169|Vega:OTTMUSG00000005479 +216724 Rufy1 MGI:MGI:2429762|Ensembl:ENSMUSG00000020375|Vega:OTTMUSG00000005584 +216725 Adamts2 MGI:MGI:1347356|Ensembl:ENSMUSG00000036545|Vega:OTTMUSG00000005590 +216739 Acsl6 MGI:MGI:894291|Ensembl:ENSMUSG00000020333|Vega:OTTMUSG00000005668 +216742 Fnip1 MGI:MGI:2444668|Ensembl:ENSMUSG00000035992|Vega:OTTMUSG00000005671 +216749 Nmur2 MGI:MGI:2441765|Ensembl:ENSMUSG00000037393|Vega:OTTMUSG00000005700 +216760 Mfap3 MGI:MGI:1924068|Ensembl:ENSMUSG00000020522|Vega:OTTMUSG00000005705 +216766 Gemin5 MGI:MGI:2449311|Ensembl:ENSMUSG00000037275|Vega:OTTMUSG00000005726 +216767 Mrpl22 MGI:MGI:1333794|Ensembl:ENSMUSG00000020514|Vega:OTTMUSG00000005722 +216781 Trim58 MGI:MGI:2684862|Ensembl:ENSMUSG00000037124|Vega:OTTMUSG00000005754 +216783 Olfr320 MGI:MGI:3030155|Ensembl:ENSMUSG00000107711|Vega:OTTMUSG00000005756 +216792 Iba57 MGI:MGI:3041174|Ensembl:ENSMUSG00000049287|Vega:OTTMUSG00000005782 +216795 Wnt9a MGI:MGI:2446084|Ensembl:ENSMUSG00000000126|Vega:OTTMUSG00000005790 +216797 Prss38 MGI:MGI:2685095|Ensembl:ENSMUSG00000049291|Vega:OTTMUSG00000005788 +216799 Nlrp3 MGI:MGI:2653833|Ensembl:ENSMUSG00000032691|Vega:OTTMUSG00000005801 +216805 Flcn MGI:MGI:2442184|Ensembl:ENSMUSG00000032633|Vega:OTTMUSG00000008092 +216810 Tom1l2 MGI:MGI:2443306|Ensembl:ENSMUSG00000000538|Vega:OTTMUSG00000005819 +216818 Gm4802 MGI:MGI:3647922 +216820 Dhrs7b MGI:MGI:2384931|Ensembl:ENSMUSG00000042569|Vega:OTTMUSG00000007771 +216821 Tmem11 MGI:MGI:2144726|Ensembl:ENSMUSG00000043284|Vega:OTTMUSG00000007749 +216825 Usp22 MGI:MGI:2144157|Ensembl:ENSMUSG00000042506|Vega:OTTMUSG00000005825 +216829 Mmgt2 MGI:MGI:2448491|Ensembl:ENSMUSG00000048497|Vega:OTTMUSG00000005867 +216831 Arhgap44 MGI:MGI:2144423|Ensembl:ENSMUSG00000033389|Vega:OTTMUSG00000005898 +216835 Usp43 MGI:MGI:2444541|Ensembl:ENSMUSG00000020905|Vega:OTTMUSG00000005934 +216846 Cntrob MGI:MGI:2443290|Ensembl:ENSMUSG00000032782|Vega:OTTMUSG00000005973 +216848 Chd3 MGI:MGI:1344395|Ensembl:ENSMUSG00000018474|Vega:OTTMUSG00000005975 +216850 Kdm6b MGI:MGI:2448492|Ensembl:ENSMUSG00000018476|Vega:OTTMUSG00000005979 +216853 Wrap53 MGI:MGI:2384933|Ensembl:ENSMUSG00000041346|Vega:OTTMUSG00000005983 +216856 Nlgn2 MGI:MGI:2681835|Ensembl:ENSMUSG00000051790|Vega:OTTMUSG00000005998 +216858 Kctd11 MGI:MGI:2448712|Ensembl:ENSMUSG00000046731|Vega:OTTMUSG00000006013 +216859 Acap1 MGI:MGI:2388270|Ensembl:ENSMUSG00000001588|Vega:OTTMUSG00000006015 +216860 Neurl4 MGI:MGI:1921092|Ensembl:ENSMUSG00000047284|Vega:OTTMUSG00000006032 +216864 Mgl2 MGI:MGI:2385729|Ensembl:ENSMUSG00000040950|Vega:OTTMUSG00000006034 +216867 Slc16a11 MGI:MGI:2663709|Ensembl:ENSMUSG00000040938|Vega:OTTMUSG00000006036 +216869 Arrb2 MGI:MGI:99474|Ensembl:ENSMUSG00000060216|Vega:OTTMUSG00000006049 +216871 Gltpd2 MGI:MGI:2444527|Ensembl:ENSMUSG00000046811|Vega:OTTMUSG00000006058 +216873 Spag7 MGI:MGI:107380|Ensembl:ENSMUSG00000018287|Vega:OTTMUSG00000006070 +216874 Camta2 MGI:MGI:2135957|Ensembl:ENSMUSG00000040712|Vega:OTTMUSG00000006066 +216877 Dhx33 MGI:MGI:2445102|Ensembl:ENSMUSG00000040620|Vega:OTTMUSG00000006082 +216881 Wscd1 MGI:MGI:2448493|Ensembl:ENSMUSG00000020811|Vega:OTTMUSG00000006094 +216892 Spns2 MGI:MGI:2384936|Ensembl:ENSMUSG00000040447|Vega:OTTMUSG00000008085 +216961 Coro6 MGI:MGI:2183448|Ensembl:ENSMUSG00000020836|Vega:OTTMUSG00000008182 +216963 Git1 MGI:MGI:1927140|Ensembl:ENSMUSG00000011877|Vega:OTTMUSG00000008178 +216964 Trp53i13 MGI:MGI:1915125|Ensembl:ENSMUSG00000044328|Vega:OTTMUSG00000008177 +216965 Taok1 MGI:MGI:1914490|Ensembl:ENSMUSG00000017291|Vega:OTTMUSG00000008181 +216971 Fam222b MGI:MGI:2384939|Ensembl:ENSMUSG00000037750|Vega:OTTMUSG00000000101 +216974 Proca1 MGI:MGI:1918274|Ensembl:ENSMUSG00000044122|Vega:OTTMUSG00000000099 +216976 BC030499 MGI:MGI:2652869 +216984 Evi2b MGI:MGI:1890682|Ensembl:ENSMUSG00000093938|Vega:OTTMUSG00000000197 +216987 Utp6 MGI:MGI:2445193|Ensembl:ENSMUSG00000035575|Vega:OTTMUSG00000000191 +216991 Adap2 MGI:MGI:2663075|Ensembl:ENSMUSG00000020709|Vega:OTTMUSG00000000213 +217011 Nle1 MGI:MGI:2429770|Ensembl:ENSMUSG00000020692|Vega:OTTMUSG00000000904 +217012 Unc45b MGI:MGI:2443377|Ensembl:ENSMUSG00000018845|Vega:OTTMUSG00000000930 +217026 Heatr6 MGI:MGI:1919790|Ensembl:ENSMUSG00000000976|Vega:OTTMUSG00000000978 +217030 Synrg MGI:MGI:1354742|Ensembl:ENSMUSG00000034940|Vega:OTTMUSG00000000989 +217031 Tada2a MGI:MGI:2144471|Ensembl:ENSMUSG00000018651|Vega:OTTMUSG00000000969 +217038 Mrm1 MGI:MGI:2443470|Ensembl:ENSMUSG00000018405|Vega:OTTMUSG00000007585 +217039 Ggnbp2 MGI:MGI:2387356|Ensembl:ENSMUSG00000020530|Vega:OTTMUSG00000001025 +217057 Ptrh2 MGI:MGI:2444848|Ensembl:ENSMUSG00000072582|Vega:OTTMUSG00000001204 +217066 Gm15698 MGI:MGI:3651308|Ensembl:ENSMUSG00000057534|Vega:OTTMUSG00000025408 +217069 Trim25 MGI:MGI:102749|Ensembl:ENSMUSG00000000275|Vega:OTTMUSG00000001304 +217071 Gm525 MGI:MGI:2685371|Ensembl:ENSMUSG00000072553|Vega:OTTMUSG00000001311 +217082 Hlf MGI:MGI:96108|Ensembl:ENSMUSG00000003949|Vega:OTTMUSG00000001287 +217109 Utp18 MGI:MGI:1923402|Ensembl:ENSMUSG00000054079|Vega:OTTMUSG00000001465 +217116 Spata20 MGI:MGI:2183449|Ensembl:ENSMUSG00000020867|Vega:OTTMUSG00000001999 +217119 Xylt2 MGI:MGI:2444797|Ensembl:ENSMUSG00000020868|Vega:OTTMUSG00000002014 +217122 Gm11545 MGI:MGI:2144683 +217124 Ppp1r9b MGI:MGI:2387581|Ensembl:ENSMUSG00000038976|Vega:OTTMUSG00000001501 +217125 Samd14 MGI:MGI:2384945|Ensembl:ENSMUSG00000047181|Vega:OTTMUSG00000001502 +217127 Kat7 MGI:MGI:2182799|Ensembl:ENSMUSG00000038909|Vega:OTTMUSG00000001619 +217138 Prr15l MGI:MGI:2387599|Ensembl:ENSMUSG00000047040|Vega:OTTMUSG00000001730 +217140 Scrn2 MGI:MGI:1343092|Ensembl:ENSMUSG00000020877|Vega:OTTMUSG00000001863 +217143 Gpr179 MGI:MGI:2443409|Ensembl:ENSMUSG00000070337|Vega:OTTMUSG00000002518 +217149 Cisd3 MGI:MGI:101788|Ensembl:ENSMUSG00000078695|Vega:OTTMUSG00000002748 +217151 Arl5c MGI:MGI:3028577|Ensembl:ENSMUSG00000038352|Vega:OTTMUSG00000002915 +217154 Stac2 MGI:MGI:2144518|Ensembl:ENSMUSG00000017400|Vega:OTTMUSG00000002905 +217166 Nr1d1 MGI:MGI:2444210|Ensembl:ENSMUSG00000020889|Vega:OTTMUSG00000006407 +217169 Tns4 MGI:MGI:2144377|Ensembl:ENSMUSG00000017607|Vega:OTTMUSG00000006443 +217194 Klhl11 MGI:MGI:2388648|Ensembl:ENSMUSG00000048732|Vega:OTTMUSG00000006269 +217198 Plekhh3 MGI:MGI:2384950|Ensembl:ENSMUSG00000035172|Vega:OTTMUSG00000002703 +217201 Rundc1 MGI:MGI:2144506|Ensembl:ENSMUSG00000035007|Vega:OTTMUSG00000002871 +217203 Tmem106a MGI:MGI:1922056|Ensembl:ENSMUSG00000034947|Vega:OTTMUSG00000002931 +217207 Dhx8 MGI:MGI:1306823|Ensembl:ENSMUSG00000034931|Vega:OTTMUSG00000002937 +217212 Pyy MGI:MGI:99924|Ensembl:ENSMUSG00000017311|Vega:OTTMUSG00000002320 +217214 Nags MGI:MGI:2387600|Ensembl:ENSMUSG00000048217|Vega:OTTMUSG00000002350 +217216 BC030867 MGI:MGI:2387601|Ensembl:ENSMUSG00000034773|Vega:OTTMUSG00000002677 +217217 Asb16 MGI:MGI:2654437|Ensembl:ENSMUSG00000034768|Vega:OTTMUSG00000002679 +217218 Atxn7l3 MGI:MGI:3036270|Ensembl:ENSMUSG00000059995|Vega:OTTMUSG00000002723 +217219 Fam171a2 MGI:MGI:2448496|Ensembl:ENSMUSG00000034685|Vega:OTTMUSG00000002855 +217232 Cdc27 MGI:MGI:102685|Ensembl:ENSMUSG00000020687|Vega:OTTMUSG00000003148 +217246 Ace3 MGI:MGI:3644400|Ensembl:ENSMUSG00000101605|Vega:OTTMUSG00000033693 +217258 Abca8a MGI:MGI:2386846|Ensembl:ENSMUSG00000041828|Vega:OTTMUSG00000003232 +217262 Abca9 MGI:MGI:2386796|Ensembl:ENSMUSG00000041797|Vega:OTTMUSG00000003233 +217265 Abca5 MGI:MGI:2386607|Ensembl:ENSMUSG00000018800|Vega:OTTMUSG00000003326 +217294 BC006965 MGI:MGI:2384955|Ensembl:ENSMUSG00000041674 +217302 Gpr142 MGI:MGI:2668437|Ensembl:ENSMUSG00000034677|Vega:OTTMUSG00000003465 +217303 Cd300a MGI:MGI:2443411|Ensembl:ENSMUSG00000034652|Vega:OTTMUSG00000003516 +217304 Cd300lb MGI:MGI:2685099|Ensembl:ENSMUSG00000063193|Vega:OTTMUSG00000003518 +217305 Cd300ld MGI:MGI:2442358|Ensembl:ENSMUSG00000034641|Vega:OTTMUSG00000003602 +217306 Cd300e MGI:MGI:2387602|Ensembl:ENSMUSG00000048498|Vega:OTTMUSG00000003608 +217310 Hid1 MGI:MGI:2445087|Ensembl:ENSMUSG00000034586|Vega:OTTMUSG00000003744 +217316 Slc16a5 MGI:MGI:2443515|Ensembl:ENSMUSG00000045775|Vega:OTTMUSG00000003442 +217325 Llgl2 MGI:MGI:1918843|Ensembl:ENSMUSG00000020782|Vega:OTTMUSG00000003613 +217328 Myo15b MGI:MGI:2685534|Ensembl:ENSMUSG00000034427|Vega:OTTMUSG00000003612 +217331 Unk MGI:MGI:2442456|Ensembl:ENSMUSG00000020770|Vega:OTTMUSG00000003686 +217333 Trim47 MGI:MGI:1917374|Ensembl:ENSMUSG00000020773|Vega:OTTMUSG00000003688 +217335 Fbf1 MGI:MGI:1922033|Ensembl:ENSMUSG00000020776|Vega:OTTMUSG00000003755 +217337 Srp68 MGI:MGI:1917447|Ensembl:ENSMUSG00000020780|Vega:OTTMUSG00000003836 +217340 Rnf157 MGI:MGI:2442484|Ensembl:ENSMUSG00000052949|Vega:OTTMUSG00000003842 +217341 Qrich2 MGI:MGI:2684912|Ensembl:ENSMUSG00000070331|Vega:OTTMUSG00000003897 +217342 Ube2o MGI:MGI:2444266|Ensembl:ENSMUSG00000020802|Vega:OTTMUSG00000003902 +217344 Rhbdf2 MGI:MGI:2442473|Ensembl:ENSMUSG00000020806|Vega:OTTMUSG00000003950 +217351 Tnrc6c MGI:MGI:2443265|Ensembl:ENSMUSG00000025571|Vega:OTTMUSG00000003674 +217353 Tmc6 MGI:MGI:1098686|Ensembl:ENSMUSG00000025572|Vega:OTTMUSG00000003673 +217356 Tmc8 MGI:MGI:2669037|Ensembl:ENSMUSG00000050106|Vega:OTTMUSG00000003679 +217364 Engase MGI:MGI:2443788|Ensembl:ENSMUSG00000033857|Vega:OTTMUSG00000003973 +217365 Nploc4 MGI:MGI:2679787|Ensembl:ENSMUSG00000039703|Vega:OTTMUSG00000004173 +217366 Lrrc45 MGI:MGI:2387183|Ensembl:ENSMUSG00000025145|Vega:OTTMUSG00000004080 +217369 Uts2r MGI:MGI:2183450|Ensembl:ENSMUSG00000039321|Vega:OTTMUSG00000004297 +217370 BC017643 MGI:MGI:2384959|Ensembl:ENSMUSG00000039294|Vega:OTTMUSG00000004288 +217371 Rab40b MGI:MGI:2183451|Ensembl:ENSMUSG00000025170|Vega:OTTMUSG00000004681 +217378 Dnajc27 MGI:MGI:2443036|Ensembl:ENSMUSG00000020657 +217379 Ubxn2a MGI:MGI:2442310|Ensembl:ENSMUSG00000020634|Vega:OTTMUSG00000033224 +217390 Gm4803 MGI:MGI:3643876 +217409 Gm4804 MGI:MGI:3646648 +217410 Trib2 MGI:MGI:2145021|Ensembl:ENSMUSG00000020601|Vega:OTTMUSG00000027552 +217430 Pqlc3 MGI:MGI:2444067|Ensembl:ENSMUSG00000045679|Vega:OTTMUSG00000027499 +217431 Nol10 MGI:MGI:2684913|Ensembl:ENSMUSG00000061458 +217449 Trappc12 MGI:MGI:2445089|Ensembl:ENSMUSG00000020628 +217463 Snx13 MGI:MGI:2661416|Ensembl:ENSMUSG00000020590 +217473 Ankmy2 MGI:MGI:2144755|Ensembl:ENSMUSG00000036188 +217480 Dgkb MGI:MGI:2442474|Ensembl:ENSMUSG00000036095 +217517 Stxbp6 MGI:MGI:2384963|Ensembl:ENSMUSG00000046314|Vega:OTTMUSG00000027623 +217536 Gm1818 MGI:MGI:3037676 +217558 G2e3 MGI:MGI:2444298|Ensembl:ENSMUSG00000035293|Vega:OTTMUSG00000031423 +217578 Baz1a MGI:MGI:1309478|Ensembl:ENSMUSG00000035021|Vega:OTTMUSG00000037585 +217588 Mbip MGI:MGI:1918320|Ensembl:ENSMUSG00000021028 +217593 Slc25a21 MGI:MGI:2445059|Ensembl:ENSMUSG00000035472|Vega:OTTMUSG00000023139 +217600 Rpl26-ps2 MGI:MGI:3648782 +217601 BC042761 MGI:MGI:2670968 +217645 Gm4806 MGI:MGI:3642945 +217647 Rpl7a-ps1 MGI:MGI:3642946 +217648 Gm527 MGI:MGI:2685373|Ensembl:ENSMUSG00000047227 +217653 Mis18bp1 MGI:MGI:2145099|Ensembl:ENSMUSG00000047534|Vega:OTTMUSG00000017447 +217664 Mgat2 MGI:MGI:2384966|Ensembl:ENSMUSG00000043998|Vega:OTTMUSG00000023816 +217666 L2hgdh MGI:MGI:2384968|Ensembl:ENSMUSG00000020988 +217674 Gphb5 MGI:MGI:2156540|Ensembl:ENSMUSG00000048982 +217682 Plekhd1 MGI:MGI:3036228|Ensembl:ENSMUSG00000066438|Vega:OTTMUSG00000033011 +217684 Susd6 MGI:MGI:2444661|Ensembl:ENSMUSG00000021133 +217692 Sipa1l1 MGI:MGI:2443679|Ensembl:ENSMUSG00000042700 +217695 Zfyve1 MGI:MGI:3026685|Ensembl:ENSMUSG00000042628 +217698 Acot5 MGI:MGI:2384969|Ensembl:ENSMUSG00000042540|Vega:OTTMUSG00000027615 +217700 Acot6 MGI:MGI:1921287|Ensembl:ENSMUSG00000043487|Vega:OTTMUSG00000027618 +217705 Fam161b MGI:MGI:2443027|Ensembl:ENSMUSG00000021234|Vega:OTTMUSG00000023376 +217707 Coq6 MGI:MGI:1924408|Ensembl:ENSMUSG00000021235|Vega:OTTMUSG00000023378 +217708 Lin52 MGI:MGI:3045391|Ensembl:ENSMUSG00000085793 +217715 Eif2b2 MGI:MGI:2145118|Ensembl:ENSMUSG00000004788|Vega:OTTMUSG00000030645 +217716 Mlh3 MGI:MGI:1353455|Ensembl:ENSMUSG00000021245 +217718 Nek9 MGI:MGI:2387995|Ensembl:ENSMUSG00000034290|Vega:OTTMUSG00000027680 +217721 Mfsd7c MGI:MGI:2384974|Ensembl:ENSMUSG00000034258 +217732 Cipc MGI:MGI:1919185|Ensembl:ENSMUSG00000034157|Vega:OTTMUSG00000047415 +217733 Tmem63c MGI:MGI:2444386|Ensembl:ENSMUSG00000034145|Vega:OTTMUSG00000025864 +217734 Pomt2 MGI:MGI:2444430|Ensembl:ENSMUSG00000034126 +217737 Ahsa1 MGI:MGI:2387603|Ensembl:ENSMUSG00000021037 +217738 Ism2 MGI:MGI:2685110|Ensembl:ENSMUSG00000050671|Vega:OTTMUSG00000032853 +217779 Lysmd1 MGI:MGI:1919409|Ensembl:ENSMUSG00000053769|Vega:OTTMUSG00000022307 +217786 Gm4808 MGI:MGI:3643062 +217826 Kcnk13 MGI:MGI:2384976|Ensembl:ENSMUSG00000045404|Vega:OTTMUSG00000029285 +217827 Nrde2 MGI:MGI:2670969|Ensembl:ENSMUSG00000021179 +217830 9030617O03Rik MGI:MGI:2444813|Ensembl:ENSMUSG00000021185|Vega:OTTMUSG00000024490 +217835 Rin3 MGI:MGI:2385708|Ensembl:ENSMUSG00000044456|Vega:OTTMUSG00000023301 +217837 Itpk1 MGI:MGI:2446159|Ensembl:ENSMUSG00000057963|Vega:OTTMUSG00000042332 +217843 Unc79 MGI:MGI:2684729|Ensembl:ENSMUSG00000021198|Vega:OTTMUSG00000037136 +217845 Ifi27l2b MGI:MGI:1916390|Ensembl:ENSMUSG00000021208|Vega:OTTMUSG00000016847 +217847 Serpina10 MGI:MGI:2667725|Ensembl:ENSMUSG00000061947|Vega:OTTMUSG00000026297 +217864 Rcor1 MGI:MGI:106340|Ensembl:ENSMUSG00000037896|Vega:OTTMUSG00000029929 +217866 Cdc42bpb MGI:MGI:2136459|Ensembl:ENSMUSG00000021279 +217869 Eif5 MGI:MGI:95309|Ensembl:ENSMUSG00000021282 +217874 Rd3l MGI:MGI:2675860|Ensembl:ENSMUSG00000091402|Vega:OTTMUSG00000045676 +217882 Cep170b MGI:MGI:2145043|Ensembl:ENSMUSG00000072825 +217887 BC022687 MGI:MGI:2443738|Ensembl:ENSMUSG00000037594 +217893 Pacs2 MGI:MGI:1924399|Ensembl:ENSMUSG00000021143 +217924 Rpl7a-ps2 MGI:MGI:3647594 +217935 Wdr60 MGI:MGI:2445085|Ensembl:ENSMUSG00000042050 +217944 Rapgef5 MGI:MGI:2444365|Ensembl:ENSMUSG00000041992 +217946 Cdca7l MGI:MGI:2384982|Ensembl:ENSMUSG00000021175|Vega:OTTMUSG00000040128 +217951 Tmem196 MGI:MGI:2685374|Ensembl:ENSMUSG00000048004|Vega:OTTMUSG00000044616 +217980 Larp4b MGI:MGI:106330|Ensembl:ENSMUSG00000033499|Vega:OTTMUSG00000048200 +217995 Heatr1 MGI:MGI:2442524|Ensembl:ENSMUSG00000050244 +218030 Pou6f2 MGI:MGI:2443631|Ensembl:ENSMUSG00000009734|Vega:OTTMUSG00000029195 +218035 Vps41 MGI:MGI:1929215|Ensembl:ENSMUSG00000041236 +218038 Amph MGI:MGI:103574|Ensembl:ENSMUSG00000021314|Vega:OTTMUSG00000054291 +218066 Olfr11 MGI:MGI:104715|Ensembl:ENSMUSG00000036658|Vega:OTTMUSG00000000439 +218100 Zfp322a MGI:MGI:2442566|Ensembl:ENSMUSG00000046351|Vega:OTTMUSG00000000548 +218102 4930558J22Rik MGI:MGI:3590517 +218103 Slc17a2 MGI:MGI:2443098|Ensembl:ENSMUSG00000036110|Vega:OTTMUSG00000000575 +218121 Mboat1 MGI:MGI:2387184|Ensembl:ENSMUSG00000038732|Vega:OTTMUSG00000000667 +218138 Gmds MGI:MGI:1891112|Ensembl:ENSMUSG00000038372|Vega:OTTMUSG00000000733 +218165 Ofcc1 MGI:MGI:2658851|Ensembl:ENSMUSG00000047094 +218194 Phactr1 MGI:MGI:2659021|Ensembl:ENSMUSG00000054728|Vega:OTTMUSG00000023876 +218203 Mylip MGI:MGI:2388271|Ensembl:ENSMUSG00000038175 +218210 Nup153 MGI:MGI:2385621|Ensembl:ENSMUSG00000021374|Vega:OTTMUSG00000043310 +218214 Kdm1b MGI:MGI:2145261|Ensembl:ENSMUSG00000038080|Vega:OTTMUSG00000024759 +218215 Rnf144b MGI:MGI:2384986|Ensembl:ENSMUSG00000038068 +218232 Ptpdc1 MGI:MGI:2145430|Ensembl:ENSMUSG00000038042 +218236 Fam120a MGI:MGI:2446163|Ensembl:ENSMUSG00000038014 +218244 Gm272 MGI:MGI:2685118 +218268 Eif4e1b MGI:MGI:2685119|Ensembl:ENSMUSG00000074895|Vega:OTTMUSG00000032677 +218271 B4galt7 MGI:MGI:2384987|Ensembl:ENSMUSG00000021504|Vega:OTTMUSG00000027738 +218274 Gm10312 MGI:MGI:3642243 +218275 BC051665 MGI:MGI:2682300|Ensembl:ENSMUSG00000042243 +218294 Cdc14b MGI:MGI:2441808|Ensembl:ENSMUSG00000033102 +218298 Gm4810 MGI:MGI:3648106 +218301 Gm4811 MGI:MGI:3648985 +218304 Prss47 MGI:MGI:2685120|Ensembl:ENSMUSG00000090658|Vega:OTTMUSG00000043485 +218311 Zfp455 MGI:MGI:3040708|Ensembl:ENSMUSG00000051037|Vega:OTTMUSG00000029819 +218314 Zfp595 MGI:MGI:3040707|Ensembl:ENSMUSG00000057842|Vega:OTTMUSG00000036831 +218332 Gm4812 MGI:MGI:3779437 +218333 Ice1 MGI:MGI:2385865|Ensembl:ENSMUSG00000034525 +218335 Clptm1l MGI:MGI:2442892|Ensembl:ENSMUSG00000021610 +218341 Rfesd MGI:MGI:2145198|Ensembl:ENSMUSG00000043190 +218343 Ttc37 MGI:MGI:2679923|Ensembl:ENSMUSG00000033991 +218368 Gm4813 MGI:MGI:3648783 +218397 Rasa1 MGI:MGI:97860|Ensembl:ENSMUSG00000021549|Vega:OTTMUSG00000016336 +218440 Ankrd34b MGI:MGI:2443245|Ensembl:ENSMUSG00000045034|Vega:OTTMUSG00000036592 +218441 Zfyve16 MGI:MGI:2145181|Ensembl:ENSMUSG00000021706|Vega:OTTMUSG00000024652 +218442 Serinc5 MGI:MGI:2444223|Ensembl:ENSMUSG00000021703 +218454 Lhfpl2 MGI:MGI:2145236|Ensembl:ENSMUSG00000045312|Vega:OTTMUSG00000027714 +218460 Wdr41 MGI:MGI:2445123|Ensembl:ENSMUSG00000042015|Vega:OTTMUSG00000035050 +218461 Pde8b MGI:MGI:2443999|Ensembl:ENSMUSG00000021684|Vega:OTTMUSG00000032523 +218476 Gcnt4 MGI:MGI:2684919|Ensembl:ENSMUSG00000091387 +218490 Btf3 MGI:MGI:1202875|Ensembl:ENSMUSG00000021660|Vega:OTTMUSG00000033602 +218501 Gm4815 MGI:MGI:3643439 +218503 Fcho2 MGI:MGI:3505790|Ensembl:ENSMUSG00000041685 +218506 Mrps27 MGI:MGI:1919064|Ensembl:ENSMUSG00000041632 +218518 Marveld2 MGI:MGI:2446166|Ensembl:ENSMUSG00000021636 +218543 Srek1 MGI:MGI:2145245|Ensembl:ENSMUSG00000032621|Vega:OTTMUSG00000061082 +218544 Sgtb MGI:MGI:2444615|Ensembl:ENSMUSG00000042743|Vega:OTTMUSG00000035056 +218581 Depdc1b MGI:MGI:2145425|Ensembl:ENSMUSG00000021697|Vega:OTTMUSG00000036632 +218613 Mier3 MGI:MGI:2442317|Ensembl:ENSMUSG00000032727|Vega:OTTMUSG00000019751 +218624 Il31ra MGI:MGI:2180511|Ensembl:ENSMUSG00000050377 +218629 Dhx29 MGI:MGI:2145374|Ensembl:ENSMUSG00000042426 +218630 Ccno MGI:MGI:2145534|Ensembl:ENSMUSG00000042417 +218639 Arl15 MGI:MGI:2442308|Ensembl:ENSMUSG00000042348|Vega:OTTMUSG00000037579 +218693 Paip1 MGI:MGI:2384993|Ensembl:ENSMUSG00000025451|Vega:OTTMUSG00000023167 +218695 Gm10044 MGI:MGI:3641749 +218699 Pxk MGI:MGI:1289230|Ensembl:ENSMUSG00000033885 +218734 3830406C13Rik MGI:MGI:1917937|Ensembl:ENSMUSG00000033111 +218739 Sntn MGI:MGI:3045373|Ensembl:ENSMUSG00000044772|Vega:OTTMUSG00000027776 +218756 Slc4a7 MGI:MGI:2443878|Ensembl:ENSMUSG00000021733 +218763 Lrrc3b MGI:MGI:2384996|Ensembl:ENSMUSG00000045201 +218772 Rarb MGI:MGI:97857|Ensembl:ENSMUSG00000017491 +218793 Ube2e2 MGI:MGI:2384997|Ensembl:ENSMUSG00000058317|Vega:OTTMUSG00000027804 +218811 Sec24c MGI:MGI:1919746|Ensembl:ENSMUSG00000039367 +218820 Zfp503 MGI:MGI:1353644|Ensembl:ENSMUSG00000039081|Vega:OTTMUSG00000036886 +218832 Polr3a MGI:MGI:2681836|Ensembl:ENSMUSG00000025280 +218850 Fam208a MGI:MGI:1921694|Ensembl:ENSMUSG00000040651 +218865 Chdh MGI:MGI:1860776|Ensembl:ENSMUSG00000015970|Vega:OTTMUSG00000027809 +218877 Sema3g MGI:MGI:3041242|Ensembl:ENSMUSG00000021904|Vega:OTTMUSG00000015259 +218885 Oxnad1 MGI:MGI:1916953|Ensembl:ENSMUSG00000021906|Vega:OTTMUSG00000035379 +218888 Gm4816 MGI:MGI:3779438 +218902 4930503F20Rik MGI:MGI:1925257 +218914 Wapl MGI:MGI:2675859|Ensembl:ENSMUSG00000041408|Vega:OTTMUSG00000024463 +218921 4930474N05Rik MGI:MGI:3586330|Ensembl:ENSMUSG00000096405|Vega:OTTMUSG00000047978 +218945 Gm4817 MGI:MGI:3644402 +218952 Fermt2 MGI:MGI:2385001|Ensembl:ENSMUSG00000037712|Vega:OTTMUSG00000026135 +218963 Gm1821 MGI:MGI:3037679 +218973 Wdhd1 MGI:MGI:2443514|Ensembl:ENSMUSG00000037572|Vega:OTTMUSG00000017452 +218975 Mapk1ip1l MGI:MGI:2444022|Ensembl:ENSMUSG00000021840 +218977 Dlgap5 MGI:MGI:2183453|Ensembl:ENSMUSG00000037544|Vega:OTTMUSG00000042413 +218989 Tmem260 MGI:MGI:2443219|Ensembl:ENSMUSG00000036339|Vega:OTTMUSG00000025627 +218993 Gm534 MGI:MGI:2685380 +218997 Rpl19-ps3 MGI:MGI:3648038 +219019 Olfr743 MGI:MGI:3030577|Ensembl:ENSMUSG00000094285|Vega:OTTMUSG00000058485 +219022 Ttc5 MGI:MGI:2683584|Ensembl:ENSMUSG00000006288 +219024 Tmem55b MGI:MGI:2448501|Ensembl:ENSMUSG00000035953|Vega:OTTMUSG00000033743 +219026 Eddm3b MGI:MGI:2684921|Ensembl:ENSMUSG00000072575 +219033 Ang4 MGI:MGI:2656551|Ensembl:ENSMUSG00000060615|Vega:OTTMUSG00000036425 +219038 Tppp2 MGI:MGI:2684923|Ensembl:ENSMUSG00000008813 +219060 B230359F08Rik MGI:MGI:3026946|IMGT/GENE-DB:TRAV13-5 +219065 A630038E17Rik MGI:MGI:2444676 +219072 Haus4 MGI:MGI:1261794|Ensembl:ENSMUSG00000022177 +219094 Khnyn MGI:MGI:2451333|Ensembl:ENSMUSG00000047153 +219102 Gm4819 MGI:MGI:3647912 +219103 Cenpj MGI:MGI:2684927|Ensembl:ENSMUSG00000064128|Vega:OTTMUSG00000019769 +219105 Zmym5 MGI:MGI:3041170|Ensembl:ENSMUSG00000040123|Vega:OTTMUSG00000037133 +219114 Ska3 MGI:MGI:3041235|Ensembl:ENSMUSG00000021965 +219131 Phf11a MGI:MGI:1918441|Ensembl:ENSMUSG00000044703|Vega:OTTMUSG00000021013 +219132 Phf11d MGI:MGI:1277133|Ensembl:ENSMUSG00000068245|Vega:OTTMUSG00000034689 +219134 Shisa2 MGI:MGI:2444716|Ensembl:ENSMUSG00000044461 +219135 Mtmr6 MGI:MGI:2145637|Ensembl:ENSMUSG00000021987 +219140 Spata13 MGI:MGI:104838|Ensembl:ENSMUSG00000021990|Vega:OTTMUSG00000035020 +219144 Arl11 MGI:MGI:2444054|Ensembl:ENSMUSG00000043157 +219148 Fam167a MGI:MGI:3606565|Ensembl:ENSMUSG00000035095|Vega:OTTMUSG00000027838 +219149 Xkr6 MGI:MGI:2447765|Ensembl:ENSMUSG00000035067|Vega:OTTMUSG00000027835 +219150 Hmbox1 MGI:MGI:2445066|Ensembl:ENSMUSG00000021972|Vega:OTTMUSG00000040027 +219151 Scara3 MGI:MGI:2444418|Ensembl:ENSMUSG00000034463 +219158 Ccar2 MGI:MGI:2444228|Ensembl:ENSMUSG00000033712 +219170 Fam216b MGI:MGI:2145738|Ensembl:ENSMUSG00000045655|Vega:OTTMUSG00000027794 +219180 Gm4821 MGI:MGI:3648787 +219181 Akap11 MGI:MGI:2684060|Ensembl:ENSMUSG00000022016|Vega:OTTMUSG00000032614 +219189 Vwa8 MGI:MGI:1919008|Ensembl:ENSMUSG00000058997 +219228 Pcdh17 MGI:MGI:2684924|Ensembl:ENSMUSG00000035566 +219249 Tdrd3 MGI:MGI:2444023|Ensembl:ENSMUSG00000022019|Vega:OTTMUSG00000035265 +219257 Pcdh20 MGI:MGI:2443376|Ensembl:ENSMUSG00000050505|Vega:OTTMUSG00000050938 +223186 Gm4822 MGI:MGI:3643987 +223227 Sox21 MGI:MGI:2654070|Ensembl:ENSMUSG00000061517|Vega:OTTMUSG00000036706 +223254 Farp1 MGI:MGI:2446173|Ensembl:ENSMUSG00000025555|Vega:OTTMUSG00000026446 +223255 Stk24 MGI:MGI:2385007|Ensembl:ENSMUSG00000063410 +223262 Timm8a2 MGI:MGI:3615492|Ensembl:ENSMUSG00000071229|Vega:OTTMUSG00000033567 +223267 Ggact MGI:MGI:2385008|Ensembl:ENSMUSG00000041625|Vega:OTTMUSG00000025741 +223272 Itgbl1 MGI:MGI:2443439|Ensembl:ENSMUSG00000032925|Vega:OTTMUSG00000027793 +223278 Gm4823 MGI:MGI:3648399 +223332 Ranbp3l MGI:MGI:2444654|Ensembl:ENSMUSG00000048424 +223337 Ugt3a2 MGI:MGI:2145969|Ensembl:ENSMUSG00000049152|Vega:OTTMUSG00000026415 +223413 9230109A22Rik MGI:MGI:2445011 +223417 Gm4824 MGI:MGI:3643521 +223431 Tiaf2 MGI:MGI:2651383 +223433 Fam105a MGI:MGI:2687281|Ensembl:ENSMUSG00000056069 +223435 Trio MGI:MGI:1927230|Ensembl:ENSMUSG00000022263 +223453 Dap MGI:MGI:1918190|Ensembl:ENSMUSG00000039168|Vega:OTTMUSG00000045678 +223455 March6 MGI:MGI:2442773|Ensembl:ENSMUSG00000039100 +223473 Nipal2 MGI:MGI:1924488|Ensembl:ENSMUSG00000038879 +223483 A830021M18Rik MGI:MGI:4437721 +223499 Dcaf13 MGI:MGI:2684929|Ensembl:ENSMUSG00000022300|Vega:OTTMUSG00000046357 +223513 Abra MGI:MGI:2444891|Ensembl:ENSMUSG00000042895 +223527 Eny2 MGI:MGI:1919286|Ensembl:ENSMUSG00000022338 +223593 Washc5 MGI:MGI:2146110|Ensembl:ENSMUSG00000022350 +223601 Fam49b MGI:MGI:1923520|Ensembl:ENSMUSG00000022378 +223604 Kcnk9 MGI:MGI:3521816|Ensembl:ENSMUSG00000036760 +223626 Them6 MGI:MGI:1925301|Ensembl:ENSMUSG00000056665|Vega:OTTMUSG00000045255 +223631 BC025446 MGI:MGI:2385015|Ensembl:ENSMUSG00000047728|Vega:OTTMUSG00000045197 +223642 Zc3h3 MGI:MGI:2663721|Ensembl:ENSMUSG00000075600 +223645 Mroh6 MGI:MGI:5011755|Ensembl:ENSMUSG00000098678|Vega:OTTMUSG00000044918 +223646 Naprt MGI:MGI:2442664|Ensembl:ENSMUSG00000022574 +223648 Ccdc166 MGI:MGI:1925902|Ensembl:ENSMUSG00000098176|Vega:OTTMUSG00000044382 +223649 Nrbp2 MGI:MGI:2385017|Ensembl:ENSMUSG00000075590 +223650 Eppk1 MGI:MGI:2386306 +223658 Mroh1 MGI:MGI:2442558|Ensembl:ENSMUSG00000022558|Vega:OTTMUSG00000032529 +223664 Lrrc14 MGI:MGI:2445060|Ensembl:ENSMUSG00000033728|Vega:OTTMUSG00000033519 +223665 C030006K11Rik MGI:MGI:1925941|Ensembl:ENSMUSG00000033707 +223666 Arhgap39 MGI:MGI:107858|Ensembl:ENSMUSG00000033697|Vega:OTTMUSG00000039938 +223669 Zfp7 MGI:MGI:99208|Ensembl:ENSMUSG00000033669 +223672 Apol9a MGI:MGI:3606001|Ensembl:ENSMUSG00000057346 +223690 Ankrd54 MGI:MGI:2444209|Ensembl:ENSMUSG00000033055|Vega:OTTMUSG00000029926 +223691 Eif3l MGI:MGI:2386251|Ensembl:ENSMUSG00000033047 +223693 Tmem184b MGI:MGI:2445179|Ensembl:ENSMUSG00000009035 +223696 Tomm22 MGI:MGI:2450248|Ensembl:ENSMUSG00000022427|Vega:OTTMUSG00000023517 +223697 Sun2 MGI:MGI:2443011|Ensembl:ENSMUSG00000042524|Vega:OTTMUSG00000034297 +223701 Mkl1 MGI:MGI:2384495|Ensembl:ENSMUSG00000042292|Vega:OTTMUSG00000034068 +223706 Cyp2d34 MGI:MGI:2385022|Ensembl:ENSMUSG00000094559 +223722 Mcat MGI:MGI:2388651|Ensembl:ENSMUSG00000048755 +223723 Ttll12 MGI:MGI:3039573|Ensembl:ENSMUSG00000016757|Vega:OTTMUSG00000023619 +223726 Mpped1 MGI:MGI:106316|Ensembl:ENSMUSG00000041708|Vega:OTTMUSG00000026120 +223732 Ldoc1l MGI:MGI:2675858|Ensembl:ENSMUSG00000055745 +223739 5031439G07Rik MGI:MGI:2444899|Ensembl:ENSMUSG00000036046|Vega:OTTMUSG00000028166 +223745 Gm4825 MGI:MGI:3647768 +223752 Gramd4 MGI:MGI:2676308|Ensembl:ENSMUSG00000035900|Vega:OTTMUSG00000025710 +223753 Cerk MGI:MGI:2386052|Ensembl:ENSMUSG00000035891|Vega:OTTMUSG00000023778 +223754 Tbc1d22a MGI:MGI:1289265|Ensembl:ENSMUSG00000051864 +223770 Brd1 MGI:MGI:1924161|Ensembl:ENSMUSG00000022387|Vega:OTTMUSG00000017296 +223773 Zbed4 MGI:MGI:2682302|Ensembl:ENSMUSG00000034333|Vega:OTTMUSG00000017462 +223774 Alg12 MGI:MGI:2385025|Ensembl:ENSMUSG00000035845|Vega:OTTMUSG00000031154 +223775 Pim3 MGI:MGI:1355297|Ensembl:ENSMUSG00000035828 +223776 Selenoo MGI:MGI:1919007|Ensembl:ENSMUSG00000035757|Vega:OTTMUSG00000021007 +223780 Adm2 MGI:MGI:2675256|Ensembl:ENSMUSG00000054136 +223809 Smgc MGI:MGI:1859618|Ensembl:ENSMUSG00000047295|Vega:OTTMUSG00000020868 +223825 Mroh2b MGI:MGI:1921905|Ensembl:ENSMUSG00000022155 +223827 Gxylt1 MGI:MGI:2684933|Ensembl:ENSMUSG00000036197|Vega:OTTMUSG00000023355 +223828 Pphln1 MGI:MGI:1917029|Ensembl:ENSMUSG00000036167 +223838 Adamts20 MGI:MGI:2660628|Ensembl:ENSMUSG00000022449|Vega:OTTMUSG00000025504 +223843 Dbx2 MGI:MGI:107445|Ensembl:ENSMUSG00000045608|Vega:OTTMUSG00000037232 +223864 Rapgef3 MGI:MGI:2441741|Ensembl:ENSMUSG00000022469|Vega:OTTMUSG00000032758 +223869 A130012F09 - +223870 Senp1 MGI:MGI:2445054|Ensembl:ENSMUSG00000033075|Vega:OTTMUSG00000042971 +223881 Rnd1 MGI:MGI:2444878|Ensembl:ENSMUSG00000054855|Vega:OTTMUSG00000029005 +223915 Krt73 MGI:MGI:3607712|Ensembl:ENSMUSG00000063661|Vega:OTTMUSG00000028000 +223917 Krt79 MGI:MGI:2385030|Ensembl:ENSMUSG00000061397|Vega:OTTMUSG00000028015 +223918 Spryd3 MGI:MGI:2446175|Ensembl:ENSMUSG00000036966|Vega:OTTMUSG00000034005 +223920 Soat2 MGI:MGI:1332226|Ensembl:ENSMUSG00000023045|Vega:OTTMUSG00000035013 +223921 Aaas MGI:MGI:2443767|Ensembl:ENSMUSG00000036678 +223922 Atf7 MGI:MGI:2443472|Ensembl:ENSMUSG00000052414|Ensembl:ENSMUSG00000099083|Vega:OTTMUSG00000044910|Vega:OTTMUSG00000044914 +223927 BC048502 MGI:MGI:2652828|Ensembl:ENSMUSG00000053508 +223970 Rmi2 MGI:MGI:2685383|Ensembl:ENSMUSG00000037991|Vega:OTTMUSG00000042784 +223978 Cpped1 MGI:MGI:2443300|Ensembl:ENSMUSG00000065979|Vega:OTTMUSG00000022421 +223989 Marf1 MGI:MGI:2444505|Ensembl:ENSMUSG00000060657 +224008 Spidr MGI:MGI:1924834|Ensembl:ENSMUSG00000041974 +224010 Rpl29-ps4 MGI:MGI:3646415 +224014 Fgd4 MGI:MGI:2183747|Ensembl:ENSMUSG00000022788|Vega:OTTMUSG00000030883 +224019 Tmem191c MGI:MGI:107238|Ensembl:ENSMUSG00000055692 +224020 Pi4ka MGI:MGI:2448506|Ensembl:ENSMUSG00000041720|Vega:OTTMUSG00000032611 +224022 Slc7a4 MGI:MGI:2146512|Ensembl:ENSMUSG00000022756|Vega:OTTMUSG00000035925 +224023 Klhl22 MGI:MGI:1337995|Ensembl:ENSMUSG00000022750|Vega:OTTMUSG00000026785 +224024 Scarf2 MGI:MGI:1858430|Ensembl:ENSMUSG00000012017 +224044 Cyp2ab1 MGI:MGI:3644957|Ensembl:ENSMUSG00000022818|Vega:OTTMUSG00000043179 +224045 Eif2b5 MGI:MGI:2446176|Ensembl:ENSMUSG00000003235|Vega:OTTMUSG00000025977 +224055 Rtp2 MGI:MGI:2685451|Ensembl:ENSMUSG00000047531 +224065 Uts2b MGI:MGI:2677064|Ensembl:ENSMUSG00000056423|Vega:OTTMUSG00000028415 +224079 Atp13a4 MGI:MGI:1924456|Ensembl:ENSMUSG00000038094|Vega:OTTMUSG00000043576 +224088 Atp13a3 MGI:MGI:2685387|Ensembl:ENSMUSG00000022533|Vega:OTTMUSG00000028859 +224090 Tmem44 MGI:MGI:1924489|Ensembl:ENSMUSG00000022537|Vega:OTTMUSG00000024220 +224092 Lsg1 MGI:MGI:107236|Ensembl:ENSMUSG00000022538|Vega:OTTMUSG00000027760 +224093 Fam43a MGI:MGI:2676309|Ensembl:ENSMUSG00000046546|Vega:OTTMUSG00000027744 +224098 Gm536 MGI:MGI:2685382 +224105 Pak2 MGI:MGI:1339984|Ensembl:ENSMUSG00000022781|Vega:OTTMUSG00000023944 +224109 Nrros MGI:MGI:2445095|Ensembl:ENSMUSG00000052384|Vega:OTTMUSG00000028939 +224111 Ubxn7 MGI:MGI:2146388|Ensembl:ENSMUSG00000053774 +224116 Muc20 MGI:MGI:2385039|Ensembl:ENSMUSG00000035638|Vega:OTTMUSG00000025214 +224129 Adcy5 MGI:MGI:99673|Ensembl:ENSMUSG00000022840 +224132 Dirc2 MGI:MGI:2387188|Ensembl:ENSMUSG00000022848|Vega:OTTMUSG00000030298 +224139 Golgb1 MGI:MGI:1099447|Ensembl:ENSMUSG00000034243|Vega:OTTMUSG00000026955 +224143 Poglut1 MGI:MGI:2444232|Ensembl:ENSMUSG00000034064|Vega:OTTMUSG00000028147 +224170 Dzip3 MGI:MGI:1917433|Ensembl:ENSMUSG00000064061|Vega:OTTMUSG00000028734 +224171 C330027C09Rik MGI:MGI:2146335|Ensembl:ENSMUSG00000033031|Vega:OTTMUSG00000028726 +224180 Gm4827 MGI:MGI:3646707 +224224 Impg2 MGI:MGI:3044955|Ensembl:ENSMUSG00000035270|Vega:OTTMUSG00000032947 +224247 E330017A01Rik MGI:MGI:3045360|Ensembl:ENSMUSG00000055789|Vega:OTTMUSG00000036766 +224250 Cldnd1 MGI:MGI:2447860|Ensembl:ENSMUSG00000022744|Vega:OTTMUSG00000028494 +224273 Crybg3 MGI:MGI:2676311|Ensembl:ENSMUSG00000022723|Vega:OTTMUSG00000027125 +224291 Csnka2ip MGI:MGI:2676295|Ensembl:ENSMUSG00000068167|Vega:OTTMUSG00000061526 +224318 Speer2 MGI:MGI:2668488|Ensembl:ENSMUSG00000063163|Vega:OTTMUSG00000036625 +224344 Rbm11 MGI:MGI:2447622|Ensembl:ENSMUSG00000032940|Vega:OTTMUSG00000019866 +224405 Cyyr1 MGI:MGI:2152187|Ensembl:ENSMUSG00000041134|Vega:OTTMUSG00000028523 +224419 Map3k7cl MGI:MGI:2446584|Ensembl:ENSMUSG00000025610|Vega:OTTMUSG00000019954 +224432 Scaf4 MGI:MGI:2146350|Ensembl:ENSMUSG00000022983 +224440 Setd4 MGI:MGI:2136890|Ensembl:ENSMUSG00000022948|Vega:OTTMUSG00000017274 +224454 Zdhhc14 MGI:MGI:2653229|Ensembl:ENSMUSG00000034265 +224460 Gm4828 MGI:MGI:3643809 +224480 Nox3 MGI:MGI:2681162|Ensembl:ENSMUSG00000023802|Vega:OTTMUSG00000021040 +224481 Tfb1m MGI:MGI:2146851|Ensembl:ENSMUSG00000036983 +224487 Gm4829 MGI:MGI:3643090 +224523 4732491K20Rik MGI:MGI:3026975|Ensembl:ENSMUSG00000097350 +224530 Acat3 MGI:MGI:109182|Ensembl:ENSMUSG00000062480|Vega:OTTMUSG00000028088 +224552 Vmn2r98 MGI:MGI:3647977|Ensembl:ENSMUSG00000096717|Vega:OTTMUSG00000039756 +224572 Vmn2r102 MGI:MGI:3647786|Ensembl:ENSMUSG00000095961|Vega:OTTMUSG00000039763 +224576 Vmn2r106 MGI:MGI:3647787|Ensembl:ENSMUSG00000091656|Vega:OTTMUSG00000039774 +224582 Vmn2r110 MGI:MGI:3644602|Ensembl:ENSMUSG00000091259|Vega:OTTMUSG00000039784 +224585 Zfp160 MGI:MGI:108187|Ensembl:ENSMUSG00000067942 +224598 Zfp758 MGI:MGI:2385044|Ensembl:ENSMUSG00000044501|Vega:OTTMUSG00000031530 +224613 Flywch1 MGI:MGI:2442638|Ensembl:ENSMUSG00000040097 +224617 Tbc1d24 MGI:MGI:2443456|Ensembl:ENSMUSG00000036473|Vega:OTTMUSG00000055777 +224619 Traf7 MGI:MGI:3042141|Ensembl:ENSMUSG00000052752|Vega:OTTMUSG00000040166 +224624 Rab40c MGI:MGI:2183454|Ensembl:ENSMUSG00000025730|Vega:OTTMUSG00000035874 +224630 Bnip1 MGI:MGI:109328|Ensembl:ENSMUSG00000024191|Vega:OTTMUSG00000028131 +224640 Lemd2 MGI:MGI:2385045|Ensembl:ENSMUSG00000044857 +224647 D17Wsu92e MGI:MGI:106281|Ensembl:ENSMUSG00000056692|Vega:OTTMUSG00000022177 +224648 Uhrf1bp1 MGI:MGI:3041238|Ensembl:ENSMUSG00000039512|Vega:OTTMUSG00000023192 +224650 Anks1 MGI:MGI:2446180|Ensembl:ENSMUSG00000024219|Vega:OTTMUSG00000024177 +224656 Zfp523 MGI:MGI:2687278|Ensembl:ENSMUSG00000024220|Vega:OTTMUSG00000023383 +224661 Slc26a8 MGI:MGI:2385046|Ensembl:ENSMUSG00000036196|Vega:OTTMUSG00000024246 +224662 4932407I05 - +224671 Btbd9 MGI:MGI:1916625|Ensembl:ENSMUSG00000062202 +224674 Slc37a1 MGI:MGI:2446181|Ensembl:ENSMUSG00000024036 +224691 Zfp472 MGI:MGI:2385049|Ensembl:ENSMUSG00000053600|Vega:OTTMUSG00000032577 +224694 Zfp81 MGI:MGI:1890752|Ensembl:ENSMUSG00000003929|Vega:OTTMUSG00000033065 +224697 Adamts10 MGI:MGI:2449112|Ensembl:ENSMUSG00000024299|Vega:OTTMUSG00000037200 +224703 March2 MGI:MGI:1925915|Ensembl:ENSMUSG00000079557|Vega:OTTMUSG00000037203 +224705 Vps52 MGI:MGI:1330304|Ensembl:ENSMUSG00000024319|Vega:OTTMUSG00000037086 +224727 Bag6 MGI:MGI:1919439|Ensembl:ENSMUSG00000024392|Vega:OTTMUSG00000037183 +224742 Abcf1 MGI:MGI:1351658|Ensembl:ENSMUSG00000038762|Vega:OTTMUSG00000037427 +224752 Obox3-ps8 MGI:MGI:3647349 +224753 H2-M10.4 MGI:MGI:1276527|Ensembl:ENSMUSG00000048231|Vega:OTTMUSG00000014941 +224754 H2-M11 MGI:MGI:2676637|Ensembl:ENSMUSG00000037537|Vega:OTTMUSG00000037484 +224756 H2-M1 MGI:MGI:95913|Ensembl:ENSMUSG00000037334|Vega:OTTMUSG00000014938 +224761 H2-M10.5 MGI:MGI:1276526|Ensembl:ENSMUSG00000037246|Vega:OTTMUSG00000037372 +224762 Trim31 MGI:MGI:2385051|Ensembl:ENSMUSG00000058063|Vega:OTTMUSG00000037382 +224763 Gm4831 MGI:MGI:3644619 +224792 Adgrf5 MGI:MGI:2182928|Ensembl:ENSMUSG00000056492 +224794 Enpp4 MGI:MGI:2682634|Ensembl:ENSMUSG00000023961|Vega:OTTMUSG00000033108 +224796 Clic5 MGI:MGI:1917912|Ensembl:ENSMUSG00000023959 +224805 Aars2 MGI:MGI:2681839|Ensembl:ENSMUSG00000023938 +224807 Tmem63b MGI:MGI:2387609|Ensembl:ENSMUSG00000036026|Vega:OTTMUSG00000031349 +224813 Lrrc73 MGI:MGI:2684934|Ensembl:ENSMUSG00000071073 +224814 Abcc10 MGI:MGI:2386976|Ensembl:ENSMUSG00000032842|Vega:OTTMUSG00000036094 +224823 Rrp36 MGI:MGI:2385053|Ensembl:ENSMUSG00000023971 +224824 Pex6 MGI:MGI:2385054|Ensembl:ENSMUSG00000002763|Vega:OTTMUSG00000026320 +224826 Ubr2 MGI:MGI:1861099|Ensembl:ENSMUSG00000023977 +224829 Trerf1 MGI:MGI:2442086 +224833 AI661453 MGI:MGI:2146908|Ensembl:ENSMUSG00000034382|Vega:OTTMUSG00000028418 +224836 Usp49 MGI:MGI:2685391|Ensembl:ENSMUSG00000090115|Vega:OTTMUSG00000018349 +224840 Treml4 MGI:MGI:1923239|Ensembl:ENSMUSG00000051682|Vega:OTTMUSG00000028419 +224860 Plcl2 MGI:MGI:1352756|Ensembl:ENSMUSG00000038910 +224876 Mark1-ps1 MGI:MGI:2685170 +224893 Zfp959 MGI:MGI:2385058|Ensembl:ENSMUSG00000003198|Vega:OTTMUSG00000045093 +224897 Dpp9 MGI:MGI:2443967|Ensembl:ENSMUSG00000001229 +224902 Safb2 MGI:MGI:2146808|Ensembl:ENSMUSG00000042625|Vega:OTTMUSG00000033212 +224903 Safb MGI:MGI:2146974|Ensembl:ENSMUSG00000071054|Vega:OTTMUSG00000043612 +224904 2410015M20Rik MGI:MGI:2442174|Ensembl:ENSMUSG00000049760 +224907 Dus3l MGI:MGI:2147092|Ensembl:ENSMUSG00000007603 +224912 Crb3 MGI:MGI:2670904|Ensembl:ENSMUSG00000044279|Vega:OTTMUSG00000035828 +224916 Vmn2r120 MGI:MGI:3644483|Ensembl:ENSMUSG00000090655|Vega:OTTMUSG00000039971 +224938 Pja2 MGI:MGI:2159342|Ensembl:ENSMUSG00000024083|Vega:OTTMUSG00000037125 +224986 A730049N16Rik MGI:MGI:2685394 +224997 Dlgap1 MGI:MGI:1346065|Ensembl:ENSMUSG00000003279|Vega:OTTMUSG00000033115 +225004 BC027072 MGI:MGI:2385061|Ensembl:ENSMUSG00000044375 +225010 Lclat1 MGI:MGI:2684937|Ensembl:ENSMUSG00000054469|Vega:OTTMUSG00000031573 +225020 Fez2 MGI:MGI:2675856|Ensembl:ENSMUSG00000056121|Vega:OTTMUSG00000022983 +225027 Srsf7 MGI:MGI:1926232|Ensembl:ENSMUSG00000024097 +225028 Map4k3 MGI:MGI:2154405|Ensembl:ENSMUSG00000024242 +225030 Kcng3 MGI:MGI:2663923|Ensembl:ENSMUSG00000045053 +225049 Ttc7 MGI:MGI:1920999|Ensembl:ENSMUSG00000036918|Vega:OTTMUSG00000028525 +225055 Fbxo11 MGI:MGI:2147134|Ensembl:ENSMUSG00000005371|Vega:OTTMUSG00000020228 +225058 Gm4832 MGI:MGI:3648524 +225115 Svil MGI:MGI:2147319|Ensembl:ENSMUSG00000024236|Vega:OTTMUSG00000033148 +225131 Wac MGI:MGI:2387357|Ensembl:ENSMUSG00000024283|Vega:OTTMUSG00000036803 +225134 Gm4833 MGI:MGI:3646586 +225152 Gjd4 MGI:MGI:2444990|Ensembl:ENSMUSG00000036855 +225155 Gm4834 MGI:MGI:3779440 +225160 Thoc1 MGI:MGI:1919668|Ensembl:ENSMUSG00000024287 +225164 Mib1 MGI:MGI:2443157|Ensembl:ENSMUSG00000024294|Vega:OTTMUSG00000028579 +225182 Rbbp8 MGI:MGI:2442995|Ensembl:ENSMUSG00000041238 +225187 Ankrd29 MGI:MGI:2687055|Ensembl:ENSMUSG00000057766|Vega:OTTMUSG00000029775 +225192 Hrh4 MGI:MGI:2429635|Ensembl:ENSMUSG00000037346 +225207 Zfp521 MGI:MGI:95459|Ensembl:ENSMUSG00000024420 +225215 Rsl24d1 MGI:MGI:2681840|Ensembl:ENSMUSG00000032215|Vega:OTTMUSG00000035636 +225228 Gm4835 MGI:MGI:3648263 +225256 Dsg1b MGI:MGI:2664357|Ensembl:ENSMUSG00000061928|Vega:OTTMUSG00000028139 +225264 Gm4837 MGI:MGI:3648677 +225266 Klhl14 MGI:MGI:1921249|Ensembl:ENSMUSG00000042514|Vega:OTTMUSG00000029781 +225280 Ino80c MGI:MGI:2443014|Ensembl:ENSMUSG00000047989|Vega:OTTMUSG00000033183 +225283 Rprd1a MGI:MGI:2385066|Ensembl:ENSMUSG00000040446 +225288 Fhod3 MGI:MGI:1925847|Ensembl:ENSMUSG00000034295 +225289 AW554918 MGI:MGI:2147376|Ensembl:ENSMUSG00000033632|Vega:OTTMUSG00000034295 +225326 Pik3c3 MGI:MGI:2445019|Ensembl:ENSMUSG00000033628|Vega:OTTMUSG00000021153 +225339 Ammecr1l MGI:MGI:2442711|Ensembl:ENSMUSG00000041915 +225341 Lims2 MGI:MGI:2385067|Ensembl:ENSMUSG00000024395 +225348 Wdr36 MGI:MGI:1917819|Ensembl:ENSMUSG00000038299 +225358 Fam13b MGI:MGI:2447834|Ensembl:ENSMUSG00000036501 +225362 Reep2 MGI:MGI:2385070|Ensembl:ENSMUSG00000038555 +225363 Etf1 MGI:MGI:2385071|Ensembl:ENSMUSG00000024360|Vega:OTTMUSG00000042433 +225372 Apbb3 MGI:MGI:108404|Ensembl:ENSMUSG00000006050 +225392 Rell2 MGI:MGI:1918044|Ensembl:ENSMUSG00000044024|Vega:OTTMUSG00000036303 +225416 Rps19-ps13 MGI:MGI:3644135 +225432 Rbm27 MGI:MGI:2147194|Ensembl:ENSMUSG00000024491 +225443 Gm94 MGI:MGI:2684940|Ensembl:ENSMUSG00000071858 +225457 Gm4839 MGI:MGI:3643691 +225467 Pggt1b MGI:MGI:1917514|Ensembl:ENSMUSG00000024477 +225468 Gm4840 MGI:MGI:3647072 +225471 Ticam2 MGI:MGI:3040056|Ensembl:ENSMUSG00000056130|Vega:OTTMUSG00000033482 +225497 Fam170a MGI:MGI:2684939|Ensembl:ENSMUSG00000035420 +225518 Prdm6 MGI:MGI:2684938|Ensembl:ENSMUSG00000069378 +225523 Cep120 MGI:MGI:2147298|Ensembl:ENSMUSG00000048799 +225579 Slc27a6 MGI:MGI:3036230|Ensembl:ENSMUSG00000024600|Vega:OTTMUSG00000029853 +225583 A730017C20Rik MGI:MGI:2442934|Ensembl:ENSMUSG00000050875|Vega:OTTMUSG00000028219 +225594 Gm4841 MGI:MGI:3643814|Ensembl:ENSMUSG00000068606 +225600 Pde6a MGI:MGI:97524|Ensembl:ENSMUSG00000024575|Vega:OTTMUSG00000028119 +225608 Sh3tc2 MGI:MGI:2444417|Ensembl:ENSMUSG00000045629 +225609 Gm9949 MGI:MGI:3647947|Ensembl:ENSMUSG00000054589 +225631 Onecut2 MGI:MGI:1891408|Ensembl:ENSMUSG00000045991|Vega:OTTMUSG00000024794 +225638 Alpk2 MGI:MGI:2449492|Ensembl:ENSMUSG00000032845|Vega:OTTMUSG00000021953 +225642 Grp MGI:MGI:95833|Ensembl:ENSMUSG00000024517|Vega:OTTMUSG00000037740 +225644 Cplx4 MGI:MGI:2685803|Ensembl:ENSMUSG00000024519 +225651 Mppe1 MGI:MGI:2661311|Ensembl:ENSMUSG00000062526 +225655 Prelid3a MGI:MGI:2442865|Ensembl:ENSMUSG00000024530 +225659 Cep76 MGI:MGI:1923401|Ensembl:ENSMUSG00000073542 +225681 Gm4842 MGI:MGI:3647064 +225724 Mapk4 MGI:MGI:2444559|Ensembl:ENSMUSG00000024558|Vega:OTTMUSG00000033283 +225742 St8sia5 MGI:MGI:109243|Ensembl:ENSMUSG00000025425|Vega:OTTMUSG00000028209 +225743 Rnf165 MGI:MGI:2444521|Ensembl:ENSMUSG00000025427|Vega:OTTMUSG00000043575 +225745 Haus1 MGI:MGI:2385076|Ensembl:ENSMUSG00000041840 +225791 Zadh2 MGI:MGI:2444835|Ensembl:ENSMUSG00000049090 +225825 Cd226 MGI:MGI:3039602|Ensembl:ENSMUSG00000034028|Vega:OTTMUSG00000014908 +225845 Pla2g16 MGI:MGI:2179715|Ensembl:ENSMUSG00000060675|Vega:OTTMUSG00000033094 +225849 Ppp2r5b MGI:MGI:2388480|Ensembl:ENSMUSG00000024777|Vega:OTTMUSG00000018606 +225852 Gm550 MGI:MGI:2685396 +225861 Snx32 MGI:MGI:2444704|Ensembl:ENSMUSG00000056185 +225865 Catsper1 MGI:MGI:2179947|Ensembl:ENSMUSG00000038498 +225870 Rin1 MGI:MGI:2385695|Ensembl:ENSMUSG00000024883 +225872 Npas4 MGI:MGI:2664186|Ensembl:ENSMUSG00000045903 +225875 Lrfn4 MGI:MGI:2385612|Ensembl:ENSMUSG00000045045|Vega:OTTMUSG00000014906 +225876 Kdm2a MGI:MGI:1354736|Ensembl:ENSMUSG00000054611|Vega:OTTMUSG00000039985 +225884 Gstp3 MGI:MGI:2385078|Ensembl:ENSMUSG00000058216|Vega:OTTMUSG00000046064 +225887 Ndufs8 MGI:MGI:2385079|Ensembl:ENSMUSG00000059734 +225888 Kmt5b MGI:MGI:2444557|Ensembl:ENSMUSG00000045098|Vega:OTTMUSG00000017297 +225895 Taf6l MGI:MGI:2444957|Ensembl:ENSMUSG00000003680|Vega:OTTMUSG00000042231 +225896 Ubxn1 MGI:MGI:1289301|Ensembl:ENSMUSG00000071655 +225898 Eml3 MGI:MGI:2387612|Ensembl:ENSMUSG00000071647 +225908 Myrf MGI:MGI:2684944|Ensembl:ENSMUSG00000036098|Vega:OTTMUSG00000047597 +225912 Cyb561a3 MGI:MGI:2686925|Ensembl:ENSMUSG00000034445 +225913 Tkfc MGI:MGI:2385084|Ensembl:ENSMUSG00000034371 +225922 Oosp2 MGI:MGI:2684945|Ensembl:ENSMUSG00000055895|Vega:OTTMUSG00000028274 +225923 Oosp3 MGI:MGI:2684943|Ensembl:ENSMUSG00000055933|Vega:OTTMUSG00000028281 +225929 Patl1 MGI:MGI:2147679|Ensembl:ENSMUSG00000046139 +225994 Nmrk1 MGI:MGI:2147434|Ensembl:ENSMUSG00000037847|Vega:OTTMUSG00000033416 +225995 D030056L22Rik MGI:MGI:3583960|Ensembl:ENSMUSG00000047044 +225997 Trpm6 MGI:MGI:2675603|Ensembl:ENSMUSG00000024727 +225998 Rorb MGI:MGI:1343464|Ensembl:ENSMUSG00000036192|Vega:OTTMUSG00000023329 +226016 Abhd17b MGI:MGI:1917816|Ensembl:ENSMUSG00000047368 +226025 Trpm3 MGI:MGI:2443101|Ensembl:ENSMUSG00000052387 +226026 Smc5 MGI:MGI:2385088|Ensembl:ENSMUSG00000024943 +226040 Tmem252 MGI:MGI:3583948|Ensembl:ENSMUSG00000048572 +226041 Pgm5 MGI:MGI:1925668|Ensembl:ENSMUSG00000041731|Vega:OTTMUSG00000028323 +226043 Cbwd1 MGI:MGI:2385089|Ensembl:ENSMUSG00000024878 +226049 Dmrt2 MGI:MGI:1330307|Ensembl:ENSMUSG00000048138 +226075 Glis3 MGI:MGI:2444289|Ensembl:ENSMUSG00000052942|Vega:OTTMUSG00000033302 +226086 Gm4844 MGI:MGI:3643046 +226089 Ric1 MGI:MGI:1924893|Ensembl:ENSMUSG00000038658|Vega:OTTMUSG00000034266 +226090 Ermp1 MGI:MGI:106250|Ensembl:ENSMUSG00000046324|Vega:OTTMUSG00000034410 +226098 Hectd2 MGI:MGI:2442663|Ensembl:ENSMUSG00000041180|Vega:OTTMUSG00000028463 +226101 Myof MGI:MGI:1919192|Ensembl:ENSMUSG00000048612 +226105 Cyp2c70 MGI:MGI:2385878|Ensembl:ENSMUSG00000060613|Vega:OTTMUSG00000036823 +226115 Opalin MGI:MGI:2657025|Ensembl:ENSMUSG00000050121 +226118 AI606181 MGI:MGI:2147586 +226122 Ubtd1 MGI:MGI:2385092|Ensembl:ENSMUSG00000025171 +226123 Morn4 MGI:MGI:2449568|Ensembl:ENSMUSG00000049670 +226139 Cox15 MGI:MGI:1920112|Ensembl:ENSMUSG00000040018|Vega:OTTMUSG00000026393 +226143 Cyp2c44 MGI:MGI:1888897|Ensembl:ENSMUSG00000025197|Vega:OTTMUSG00000061612 +226144 Erlin1 MGI:MGI:2387613|Ensembl:ENSMUSG00000025198|Vega:OTTMUSG00000035208 +226151 Slf2 MGI:MGI:1924968|Ensembl:ENSMUSG00000036097 +226153 Twnk MGI:MGI:2137410|Ensembl:ENSMUSG00000025209 +226154 Lzts2 MGI:MGI:2385095|Ensembl:ENSMUSG00000035342 +226162 Dpcd MGI:MGI:1924407|Ensembl:ENSMUSG00000041035 +226169 Pprc1 MGI:MGI:2385096|Ensembl:ENSMUSG00000055491|Vega:OTTMUSG00000023305 +226178 Wbp1l MGI:MGI:107577|Ensembl:ENSMUSG00000047731|Vega:OTTMUSG00000032998 +226180 Ina MGI:MGI:96568|Ensembl:ENSMUSG00000034336|Vega:OTTMUSG00000016340 +226182 Taf5 MGI:MGI:2442144|Ensembl:ENSMUSG00000025049 +226243 Habp2 MGI:MGI:1196378|Ensembl:ENSMUSG00000025075|Vega:OTTMUSG00000036781 +226245 Plekhs1 MGI:MGI:2443041|Ensembl:ENSMUSG00000035818 +226250 Afap1l2 MGI:MGI:2147658|Ensembl:ENSMUSG00000025083|Vega:OTTMUSG00000028250 +226251 Ablim1 MGI:MGI:1194500|Ensembl:ENSMUSG00000025085|Vega:OTTMUSG00000016380 +226252 Fam160b1 MGI:MGI:2147545|Ensembl:ENSMUSG00000033478 +226255 Atrnl1 MGI:MGI:2147749|Ensembl:ENSMUSG00000054843 +226265 Eno4 MGI:MGI:2441717|Ensembl:ENSMUSG00000048029|Vega:OTTMUSG00000056180 +226278 Prlhr MGI:MGI:2135956|Ensembl:ENSMUSG00000045052 +226304 Npbwr1 MGI:MGI:891989|Ensembl:ENSMUSG00000033774|Vega:OTTMUSG00000050228 +226351 Tmem185b MGI:MGI:1917634|Ensembl:ENSMUSG00000098923|Vega:OTTMUSG00000044568 +226352 Epb41l5 MGI:MGI:103006|Ensembl:ENSMUSG00000026383|Vega:OTTMUSG00000049017 +226356 Cfap221 MGI:MGI:2684947|Ensembl:ENSMUSG00000036962|Vega:OTTMUSG00000035381 +226359 C1ql2 MGI:MGI:3032521|Ensembl:ENSMUSG00000036907|Vega:OTTMUSG00000049073 +226407 Rab3gap1 MGI:MGI:2445001|Ensembl:ENSMUSG00000036104|Vega:OTTMUSG00000025233 +226409 Zranb3 MGI:MGI:1918362|Ensembl:ENSMUSG00000036086|Vega:OTTMUSG00000017423 +226412 R3hdm1 MGI:MGI:2448514|Ensembl:ENSMUSG00000056211|Vega:OTTMUSG00000049353 +226413 Lct MGI:MGI:104576|Ensembl:ENSMUSG00000026354|Vega:OTTMUSG00000030320 +226414 Dars MGI:MGI:2442544|Ensembl:ENSMUSG00000026356|Vega:OTTMUSG00000049561 +226418 Yod1 MGI:MGI:2442596|Ensembl:ENSMUSG00000046404|Vega:OTTMUSG00000049609 +226419 Dyrk3 MGI:MGI:1330300|Ensembl:ENSMUSG00000016526|Vega:OTTMUSG00000049119 +226421 Rab7b MGI:MGI:2442295|Ensembl:ENSMUSG00000052688|Vega:OTTMUSG00000026757 +226422 Rab29 MGI:MGI:2385107|Ensembl:ENSMUSG00000026433|Vega:OTTMUSG00000017320 +226432 Ipo9 MGI:MGI:1918944|Ensembl:ENSMUSG00000041879|Vega:OTTMUSG00000034791 +226438 Igfn1 MGI:MGI:3045352|Ensembl:ENSMUSG00000051985|Vega:OTTMUSG00000019636 +226439 Ascl5 MGI:MGI:2685043|Ensembl:ENSMUSG00000097918|Vega:OTTMUSG00000042967 +226442 Zfp281 MGI:MGI:3029290|Ensembl:ENSMUSG00000041483|Vega:OTTMUSG00000022094 +226470 Zbtb41 MGI:MGI:2444487|Ensembl:ENSMUSG00000033964|Vega:OTTMUSG00000050595 +226472 Gm4845 MGI:MGI:3648781 +226499 BC003331 MGI:MGI:2385108|Ensembl:ENSMUSG00000006010|Vega:OTTMUSG00000021629 +226517 Smg7 MGI:MGI:2682334|Ensembl:ENSMUSG00000042772|Vega:OTTMUSG00000049697 +226518 Nmnat2 MGI:MGI:2444155|Ensembl:ENSMUSG00000042751|Vega:OTTMUSG00000049702 +226519 Lamc1 MGI:MGI:99914|Ensembl:ENSMUSG00000026478|Vega:OTTMUSG00000030992 +226525 Rasal2 MGI:MGI:2443881|Ensembl:ENSMUSG00000070565|Vega:OTTMUSG00000033172 +226527 BC026585 MGI:MGI:2448516|Ensembl:ENSMUSG00000033488|Vega:OTTMUSG00000023034 +226539 Dars2 MGI:MGI:2442510|Ensembl:ENSMUSG00000026709|Vega:OTTMUSG00000031015 +226541 Klhl20 MGI:MGI:2444855|Ensembl:ENSMUSG00000026705|Vega:OTTMUSG00000021980 +226548 Aph1a MGI:MGI:2385110|Ensembl:ENSMUSG00000015750|Vega:OTTMUSG00000053041 +226551 Suco MGI:MGI:2138346|Ensembl:ENSMUSG00000040297|Vega:OTTMUSG00000050995 +226562 Prrc2c MGI:MGI:1913754|Ensembl:ENSMUSG00000040225|Vega:OTTMUSG00000043447 +226564 Fmo4 MGI:MGI:2429497|Ensembl:ENSMUSG00000026692|Vega:OTTMUSG00000021469 +226565 Fmo6 MGI:MGI:2681841|Ensembl:ENSMUSG00000095576|Vega:OTTMUSG00000051983 +226591 Tiprl MGI:MGI:1915087|Ensembl:ENSMUSG00000040843|Vega:OTTMUSG00000029649 +226594 Rcsd1 MGI:MGI:2676394|Ensembl:ENSMUSG00000040723|Vega:OTTMUSG00000050544 +226601 Gm4846 MGI:MGI:3643319|Ensembl:ENSMUSG00000086056|Vega:OTTMUSG00000033784 +226604 Gm4847 MGI:MGI:3643320|Ensembl:ENSMUSG00000051081|Vega:OTTMUSG00000029828 +226610 Fam78b MGI:MGI:2443050|Ensembl:ENSMUSG00000060568|Vega:OTTMUSG00000033956 +226641 Atf6 MGI:MGI:1926157|Ensembl:ENSMUSG00000026663|Vega:OTTMUSG00000043564 +226646 Ndufs2 MGI:MGI:2385112|Ensembl:ENSMUSG00000013593|Vega:OTTMUSG00000021571 +226652 Arhgap30 MGI:MGI:2684948|Ensembl:ENSMUSG00000048865|Vega:OTTMUSG00000021534 +226654 Tstd1 MGI:MGI:3648482|Ensembl:ENSMUSG00000103711|Vega:OTTMUSG00000050080 +226691 Ifi207 MGI:MGI:2138302|Ensembl:ENSMUSG00000073490|Vega:OTTMUSG00000033916 +226695 Ifi205 MGI:MGI:101847|Ensembl:ENSMUSG00000054203|Vega:OTTMUSG00000050206 +226720 Becn2 MGI:MGI:2684950|Ensembl:ENSMUSG00000104158|Vega:OTTMUSG00000050256 +226744 Cnst MGI:MGI:2445141|Ensembl:ENSMUSG00000038949|Vega:OTTMUSG00000022551 +226747 Ahctf1 MGI:MGI:1915033|Ensembl:ENSMUSG00000026491|Vega:OTTMUSG00000033771 +226751 Cdc42bpa MGI:MGI:2441841|Ensembl:ENSMUSG00000026490|Vega:OTTMUSG00000021765 +226757 Wdr26 MGI:MGI:1923825|Ensembl:ENSMUSG00000038733|Vega:OTTMUSG00000034873 +226777 C130074G19Rik MGI:MGI:2444831|Ensembl:ENSMUSG00000039349|Vega:OTTMUSG00000029896 +226778 Mark1 MGI:MGI:2664902|Ensembl:ENSMUSG00000026620|Vega:OTTMUSG00000050984 +226781 Slc30a10 MGI:MGI:2685058|Ensembl:ENSMUSG00000026614 +226791 Lyplal1 MGI:MGI:2385115|Ensembl:ENSMUSG00000039246|Vega:OTTMUSG00000027017 +226823 Kctd3 MGI:MGI:2444629|Ensembl:ENSMUSG00000026608|Vega:OTTMUSG00000050925 +226830 Smyd2 MGI:MGI:1915889|Ensembl:ENSMUSG00000026603|Vega:OTTMUSG00000017096 +226841 Vash2 MGI:MGI:2444826|Ensembl:ENSMUSG00000037568|Vega:OTTMUSG00000051246 +226844 Mfsd7b MGI:MGI:2444881|Ensembl:ENSMUSG00000066595|Vega:OTTMUSG00000051405 +226849 Ppp2r5a MGI:MGI:2388479|Ensembl:ENSMUSG00000026626|Vega:OTTMUSG00000051528 +226856 Lpgat1 MGI:MGI:2446186|Ensembl:ENSMUSG00000026623|Vega:OTTMUSG00000021870 +226861 Hhat MGI:MGI:2444681|Ensembl:ENSMUSG00000037375|Vega:OTTMUSG00000027097 +226866 Sbspon MGI:MGI:2684952|Ensembl:ENSMUSG00000032719|Vega:OTTMUSG00000026417 +226896 Tfap2d MGI:MGI:2153466|Ensembl:ENSMUSG00000042596|Vega:OTTMUSG00000026492 +226901 Gm4849 MGI:MGI:3645366 +226922 Kcnq5 MGI:MGI:1924937|Ensembl:ENSMUSG00000028033|Vega:OTTMUSG00000019675 +226957 Gm4850 MGI:MGI:3647946 +226970 Arhgef4 MGI:MGI:2442507|Ensembl:ENSMUSG00000037509|Vega:OTTMUSG00000033276 +226971 Plekhb2 MGI:MGI:2385825|Ensembl:ENSMUSG00000026123|Vega:OTTMUSG00000029565 +226976 Kansl3 MGI:MGI:1918055|Ensembl:ENSMUSG00000010453|Vega:OTTMUSG00000049477 +226977 Actr1b MGI:MGI:1917446|Ensembl:ENSMUSG00000037351|Vega:OTTMUSG00000034164 +226982 Eif5b MGI:MGI:2441772|Ensembl:ENSMUSG00000026083|Vega:OTTMUSG00000049483 +226999 Slc9a2 MGI:MGI:105075|Ensembl:ENSMUSG00000026062|Vega:OTTMUSG00000050475 +227054 Rpl23a-ps1 MGI:MGI:3646201 +227058 Dnah7b MGI:MGI:2684953|Ensembl:ENSMUSG00000041144|Vega:OTTMUSG00000046662 +227059 Slc39a10 MGI:MGI:1914515|Ensembl:ENSMUSG00000025986|Vega:OTTMUSG00000021430 +227061 Gm4852 MGI:MGI:3643039 +227091 Gm553 MGI:MGI:2685399 +227094 Nemp2 MGI:MGI:2444113|Ensembl:ENSMUSG00000043015|Vega:OTTMUSG00000046917 +227095 Hibch MGI:MGI:1923792|Ensembl:ENSMUSG00000041426|Vega:OTTMUSG00000030558 +227099 Pms1 MGI:MGI:1202302|Ensembl:ENSMUSG00000026098|Vega:OTTMUSG00000021891 +227102 Ormdl1 MGI:MGI:2181669|Ensembl:ENSMUSG00000026097|Vega:OTTMUSG00000021828 +227112 Gm4853 MGI:MGI:3644655 +227120 Plcl1 MGI:MGI:3036262|Ensembl:ENSMUSG00000038349|Vega:OTTMUSG00000046977 +227154 Stradb MGI:MGI:2144047|Ensembl:ENSMUSG00000026027|Vega:OTTMUSG00000021303 +227157 Mpp4 MGI:MGI:2386681|Ensembl:ENSMUSG00000079550|Vega:OTTMUSG00000047223 +227195 Ino80d MGI:MGI:3027003|Ensembl:ENSMUSG00000040865|Vega:OTTMUSG00000002593 +227197 Ndufs1 MGI:MGI:2443241|Ensembl:ENSMUSG00000025968|Vega:OTTMUSG00000002613 +227210 Ccnyl1 MGI:MGI:2138614|Ensembl:ENSMUSG00000070871|Vega:OTTMUSG00000021538 +227231 Cps1 MGI:MGI:891996|Ensembl:ENSMUSG00000025991|Vega:OTTMUSG00000026539 +227288 Cxcr1 MGI:MGI:2448715|Ensembl:ENSMUSG00000048480|Vega:OTTMUSG00000021550 +227289 Gpbar1 MGI:MGI:2653863|Ensembl:ENSMUSG00000064272|Vega:OTTMUSG00000047666 +227290 Aamp MGI:MGI:107809|Ensembl:ENSMUSG00000006299|Vega:OTTMUSG00000047667 +227292 Ctdsp1 MGI:MGI:2654470|Ensembl:ENSMUSG00000026176|Vega:OTTMUSG00000021740 +227298 Retreg2 MGI:MGI:2388278|Ensembl:ENSMUSG00000049339|Vega:OTTMUSG00000048449 +227325 Dner MGI:MGI:2152889|Ensembl:ENSMUSG00000036766|Vega:OTTMUSG00000048002 +227326 Gpr55 MGI:MGI:2685064|Ensembl:ENSMUSG00000049608|Vega:OTTMUSG00000048041 +227327 B3gnt7 MGI:MGI:2384394|Ensembl:ENSMUSG00000079445|Vega:OTTMUSG00000048090 +227331 Gigyf2 MGI:MGI:2138584|Ensembl:ENSMUSG00000048000|Vega:OTTMUSG00000037064 +227333 Dgkd MGI:MGI:2138334|Ensembl:ENSMUSG00000070738|Vega:OTTMUSG00000048195 +227334 Usp40 MGI:MGI:2443184|Ensembl:ENSMUSG00000005501|Vega:OTTMUSG00000048199 +227357 Espnl MGI:MGI:2685402|Ensembl:ENSMUSG00000049515|Vega:OTTMUSG00000022701 +227358 Erfe MGI:MGI:3606476|Ensembl:ENSMUSG00000047443|Vega:OTTMUSG00000048491 +227377 Farp2 MGI:MGI:2385126|Ensembl:ENSMUSG00000034066|Vega:OTTMUSG00000026441 +227393 Gm1833 MGI:MGI:3037691 +227394 Slco4c1 MGI:MGI:2442784|Ensembl:ENSMUSG00000040693|Vega:OTTMUSG00000048777 +227399 Ppip5k2 MGI:MGI:2142810|Ensembl:ENSMUSG00000040648|Vega:OTTMUSG00000021900 +227446 2310035C23Rik MGI:MGI:1922832|Ensembl:ENSMUSG00000026319|Vega:OTTMUSG00000048965 +227449 Zcchc2 MGI:MGI:2444114|Ensembl:ENSMUSG00000038866|Vega:OTTMUSG00000026946 +227485 Cdh19 MGI:MGI:3588198|Ensembl:ENSMUSG00000047216|Vega:OTTMUSG00000048849 +227506 Gm4854 MGI:MGI:3643638 +227522 Rpp38 MGI:MGI:2443607|Ensembl:ENSMUSG00000049950|Vega:OTTMUSG00000010784 +227525 Dclre1c MGI:MGI:2441769|Ensembl:ENSMUSG00000026648|Vega:OTTMUSG00000010775 +227526 Cdnf MGI:MGI:3606576|Ensembl:ENSMUSG00000039496|Vega:OTTMUSG00000010786 +227541 Camk1d MGI:MGI:2442190|Ensembl:ENSMUSG00000039145|Vega:OTTMUSG00000010993 +227545 Proser2 MGI:MGI:2442238|Ensembl:ENSMUSG00000045319|Vega:OTTMUSG00000011753 +227580 C1ql3 MGI:MGI:2387350|Ensembl:ENSMUSG00000049630|Vega:OTTMUSG00000011228 +227588 Gm13368 MGI:MGI:3651966 +227606 Tbpl2 MGI:MGI:2684058|Ensembl:ENSMUSG00000061809|Vega:OTTMUSG00000011801 +227612 Tor4a MGI:MGI:2442720|Ensembl:ENSMUSG00000059555|Vega:OTTMUSG00000011777 +227613 Tubb4b MGI:MGI:1915472|Ensembl:ENSMUSG00000036752|Vega:OTTMUSG00000011806 +227615 Tmem203 MGI:MGI:2443597|Ensembl:ENSMUSG00000078201|Vega:OTTMUSG00000011903 +227618 Lrrc26 MGI:MGI:2385129|Ensembl:ENSMUSG00000026961|Vega:OTTMUSG00000011934 +227619 Man1b1 MGI:MGI:2684954|Ensembl:ENSMUSG00000036646|Vega:OTTMUSG00000011996 +227620 Uap1l1 MGI:MGI:2443318|Ensembl:ENSMUSG00000026956|Vega:OTTMUSG00000012027 +227622 Paxx MGI:MGI:2442831|Ensembl:ENSMUSG00000047617|Vega:OTTMUSG00000012109 +227624 Rabl6 MGI:MGI:2442633|Ensembl:ENSMUSG00000015087|Vega:OTTMUSG00000012248 +227627 Obp2a MGI:MGI:2387617|Ensembl:ENSMUSG00000062061|Vega:OTTMUSG00000012515 +227630 Lcn11 MGI:MGI:2684955|Ensembl:ENSMUSG00000069080|Vega:OTTMUSG00000012625 +227631 Sohlh1 MGI:MGI:2684956|Ensembl:ENSMUSG00000059625|Vega:OTTMUSG00000012626 +227632 Kcnt1 MGI:MGI:1924627|Ensembl:ENSMUSG00000058740|Vega:OTTMUSG00000012660 +227634 Camsap1 MGI:MGI:3036242|Ensembl:ENSMUSG00000026933|Vega:OTTMUSG00000012659 +227638 Qsox2 MGI:MGI:2387194|Ensembl:ENSMUSG00000036327|Vega:OTTMUSG00000012731 +227644 Snapc4 MGI:MGI:2443935|Ensembl:ENSMUSG00000036281|Vega:OTTMUSG00000012774 +227648 Sec16a MGI:MGI:2139207|Ensembl:ENSMUSG00000026924|Vega:OTTMUSG00000012771 +227656 Rexo4 MGI:MGI:2684957|Ensembl:ENSMUSG00000052406|Vega:OTTMUSG00000011840 +227659 Slc2a6 MGI:MGI:2443286|Ensembl:ENSMUSG00000036067|Vega:OTTMUSG00000011843 +227671 Gbgt1 MGI:MGI:2449143|Ensembl:ENSMUSG00000026829|Vega:OTTMUSG00000011649 +227674 Ddx31 MGI:MGI:2682639|Ensembl:ENSMUSG00000026806|Vega:OTTMUSG00000011764 +227682 Trub2 MGI:MGI:2442186|Ensembl:ENSMUSG00000039826|Vega:OTTMUSG00000012690 +227683 Coq4 MGI:MGI:1098826|Ensembl:ENSMUSG00000026798|Vega:OTTMUSG00000012685 +227693 Zer1 MGI:MGI:2442511|Ensembl:ENSMUSG00000039686|Vega:OTTMUSG00000016742 +227695 Spout1 MGI:MGI:106544|Ensembl:ENSMUSG00000039660|Vega:OTTMUSG00000016747 +227696 Phyhd1 MGI:MGI:3612860|Ensembl:ENSMUSG00000079484|Vega:OTTMUSG00000016754 +227697 Dolk MGI:MGI:2677836|Ensembl:ENSMUSG00000075419|Vega:OTTMUSG00000016769 +227699 Nup188 MGI:MGI:2446190|Ensembl:ENSMUSG00000052533|Vega:OTTMUSG00000016767 +227700 Sh3glb2 MGI:MGI:2385131|Ensembl:ENSMUSG00000026860|Vega:OTTMUSG00000016768 +227707 BC005624 MGI:MGI:2385132|Ensembl:ENSMUSG00000026851|Vega:OTTMUSG00000011874 +227715 Exosc2 MGI:MGI:2385133|Ensembl:ENSMUSG00000039356|Vega:OTTMUSG00000012075 +227717 Qrfp MGI:MGI:3630329|Ensembl:ENSMUSG00000043102|Vega:OTTMUSG00000012081 +227720 Nup214 MGI:MGI:1095411|Ensembl:ENSMUSG00000001855|Vega:OTTMUSG00000012954 +227721 Plpp7 MGI:MGI:2445183|Ensembl:ENSMUSG00000051373|Vega:OTTMUSG00000012943 +227723 Prrc2b MGI:MGI:1923304|Ensembl:ENSMUSG00000039262|Vega:OTTMUSG00000012946 +227731 Slc25a25 MGI:MGI:1915913|Ensembl:ENSMUSG00000026819|Vega:OTTMUSG00000011993 +227733 Pip5kl1 MGI:MGI:2448520|Ensembl:ENSMUSG00000046854|Vega:OTTMUSG00000011983 +227736 Cfap157 MGI:MGI:2447809|Ensembl:ENSMUSG00000038987|Vega:OTTMUSG00000012529 +227737 Fam129b MGI:MGI:2442910|Ensembl:ENSMUSG00000026796|Vega:OTTMUSG00000012546 +227738 Lrsam1 MGI:MGI:2684789|Ensembl:ENSMUSG00000026792|Vega:OTTMUSG00000012573 +227743 Mapkap1 MGI:MGI:2444554|Ensembl:ENSMUSG00000038696|Vega:OTTMUSG00000011942 +227746 Rabepk MGI:MGI:2139530|Ensembl:ENSMUSG00000070953|Vega:OTTMUSG00000012015 +227753 Gsn MGI:MGI:95851|Ensembl:ENSMUSG00000026879|Vega:OTTMUSG00000012088 +227789 Olfr358 MGI:MGI:3030192|Ensembl:ENSMUSG00000075379|Vega:OTTMUSG00000012224 +227794 Olfr364-ps1 MGI:MGI:3030198 +227800 Rabgap1 MGI:MGI:2385139|Ensembl:ENSMUSG00000035437|Vega:OTTMUSG00000012651 +227801 Dennd1a MGI:MGI:2442794|Ensembl:ENSMUSG00000035392|Vega:OTTMUSG00000012743 +227835 Gtdc1 MGI:MGI:2444269|Ensembl:ENSMUSG00000036890|Vega:OTTMUSG00000012356 +227867 Epc2 MGI:MGI:1278321|Ensembl:ENSMUSG00000069495|Vega:OTTMUSG00000012480 +227885 Gm13498 MGI:MGI:3650381|Ensembl:ENSMUSG00000083270 +227920 Gm13527 MGI:MGI:3651877 +227923 A930012O16Rik MGI:MGI:2442255 +227929 Cytip MGI:MGI:2183535|Ensembl:ENSMUSG00000026832|Vega:OTTMUSG00000012676 +227933 Ccdc148 MGI:MGI:3039583|Ensembl:ENSMUSG00000036641|Vega:OTTMUSG00000012754 +227937 Pkp4 MGI:MGI:109281|Ensembl:ENSMUSG00000026991|Vega:OTTMUSG00000012706 +227960 Gca MGI:MGI:1918521|Ensembl:ENSMUSG00000026893|Vega:OTTMUSG00000012870 +227995 Gm13607 MGI:MGI:3649691 +227998 4933409G03Rik MGI:MGI:3045336|Ensembl:ENSMUSG00000053896|Vega:OTTMUSG00000012891 +228003 Klhl41 MGI:MGI:2683854|Ensembl:ENSMUSG00000075307|Vega:OTTMUSG00000013007 +228005 Ppig MGI:MGI:2445173|Ensembl:ENSMUSG00000042133|Vega:OTTMUSG00000013009 +228012 Tlk1 MGI:MGI:2441683|Ensembl:ENSMUSG00000041997|Vega:OTTMUSG00000013119 +228019 Mettl8 MGI:MGI:2385142|Ensembl:ENSMUSG00000041975|Vega:OTTMUSG00000013143 +228025 Gm17250 MGI:MGI:4936884 +228026 Pdk1 MGI:MGI:1926119|Ensembl:ENSMUSG00000006494|Vega:OTTMUSG00000013264 +228033 Atp5g3 MGI:MGI:2442035|Ensembl:ENSMUSG00000018770|Vega:OTTMUSG00000013287 +228036 A630050E04Rik MGI:MGI:2685403|Ensembl:ENSMUSG00000085387 +228061 Agps MGI:MGI:2443065|Ensembl:ENSMUSG00000042410|Vega:OTTMUSG00000013293 +228071 Sestd1 MGI:MGI:1916262|Ensembl:ENSMUSG00000042272|Vega:OTTMUSG00000013223 +228094 Cerkl MGI:MGI:3037816|Ensembl:ENSMUSG00000075256|Vega:OTTMUSG00000013312 +228116 A130030D18Rik MGI:MGI:2685404|Ensembl:ENSMUSG00000087061 +228136 Zdhhc5 MGI:MGI:1923573|Ensembl:ENSMUSG00000034075|Vega:OTTMUSG00000013523 +228139 P2rx3 MGI:MGI:1097160|Ensembl:ENSMUSG00000027071|Vega:OTTMUSG00000013455 +228140 Tnks1bp1 MGI:MGI:2446193|Ensembl:ENSMUSG00000033955|Vega:OTTMUSG00000013461 +228151 4833423E24Rik MGI:MGI:2687041|Ensembl:ENSMUSG00000075217|Vega:OTTMUSG00000013491 +228228 Olfr1102 MGI:MGI:3030936|Ensembl:ENSMUSG00000049843|Vega:OTTMUSG00000013700 +228238 Gm13730 MGI:MGI:3649732 +228355 Madd MGI:MGI:2444672|Ensembl:ENSMUSG00000040687|Vega:OTTMUSG00000014395 +228356 1110051M20Rik MGI:MGI:1915079|Ensembl:ENSMUSG00000040591|Vega:OTTMUSG00000014431 +228357 Lrp4 MGI:MGI:2442252|Ensembl:ENSMUSG00000027253|Vega:OTTMUSG00000014247 +228359 Arhgap1 MGI:MGI:2445003|Ensembl:ENSMUSG00000027247|Vega:OTTMUSG00000014300 +228361 Ambra1 MGI:MGI:2443564|Ensembl:ENSMUSG00000040506|Vega:OTTMUSG00000014330 +228366 Large2 MGI:MGI:2443769|Ensembl:ENSMUSG00000040434|Vega:OTTMUSG00000014471 +228368 Slc35c1 MGI:MGI:2443301|Ensembl:ENSMUSG00000049922|Vega:OTTMUSG00000014574 +228410 Cstf3 MGI:MGI:1351825|Ensembl:ENSMUSG00000027176|Vega:OTTMUSG00000014953 +228413 Prrg4 MGI:MGI:2442211|Ensembl:ENSMUSG00000027171|Vega:OTTMUSG00000014971 +228421 Kif18a MGI:MGI:2446977|Ensembl:ENSMUSG00000027115|Vega:OTTMUSG00000015098 +228432 Ano3 MGI:MGI:3613666|Ensembl:ENSMUSG00000074968|Vega:OTTMUSG00000015134 +228443 Olfr1283 MGI:MGI:3031117|Ensembl:ENSMUSG00000109322|Vega:OTTMUSG00000015073 +228482 Arhgap11a MGI:MGI:2444300|Ensembl:ENSMUSG00000041219|Vega:OTTMUSG00000015203 +228491 Zfp770 MGI:MGI:2445100|Ensembl:ENSMUSG00000040321|Vega:OTTMUSG00000015214 +228536 Bahd1 MGI:MGI:2139371|Ensembl:ENSMUSG00000040007|Vega:OTTMUSG00000015641 +228543 Rhov MGI:MGI:2444227|Ensembl:ENSMUSG00000034226|Vega:OTTMUSG00000015878 +228545 Vps18 MGI:MGI:2443626|Ensembl:ENSMUSG00000034216|Vega:OTTMUSG00000015944 +228550 Itpka MGI:MGI:1333822|Ensembl:ENSMUSG00000027296|Vega:OTTMUSG00000016426 +228564 Frmd5 MGI:MGI:2442557|Ensembl:ENSMUSG00000027238|Vega:OTTMUSG00000015377 +228576 Mall MGI:MGI:2385152|Ensembl:ENSMUSG00000027377|Vega:OTTMUSG00000016094 +228592 F830045P16Rik MGI:MGI:3045317|Ensembl:ENSMUSG00000043727|Vega:OTTMUSG00000015525 +228598 Ebf4 MGI:MGI:2385972|Ensembl:ENSMUSG00000053552|Vega:OTTMUSG00000015516 +228602 4930402H24Rik MGI:MGI:1923029|Ensembl:ENSMUSG00000027309|Vega:OTTMUSG00000015492 +228607 Mavs MGI:MGI:2444773|Ensembl:ENSMUSG00000037523|Vega:OTTMUSG00000016041 +228608 Smox MGI:MGI:2445356|Ensembl:ENSMUSG00000027333|Vega:OTTMUSG00000016182 +228642 BC034902 MGI:MGI:2677839 +228662 Btbd3 MGI:MGI:2385155|Ensembl:ENSMUSG00000062098|Vega:OTTMUSG00000014870 +228677 Sptlc3 MGI:MGI:2444678|Ensembl:ENSMUSG00000039092|Vega:OTTMUSG00000015585 +228684 Sel1l2 MGI:MGI:2684964|Ensembl:ENSMUSG00000074764|Vega:OTTMUSG00000015603 +228714 Kat14 MGI:MGI:1917264|Ensembl:ENSMUSG00000027425|Vega:OTTMUSG00000003524 +228715 Smim26 MGI:MGI:2685407|Ensembl:ENSMUSG00000074754|Vega:OTTMUSG00000003920 +228730 Kiz MGI:MGI:2684960|Ensembl:ENSMUSG00000074749|Vega:OTTMUSG00000015699 +228731 Nkx2-4 MGI:MGI:97349|Ensembl:ENSMUSG00000054160|Vega:OTTMUSG00000015700 +228756 Cstl1 MGI:MGI:2652834|Ensembl:ENSMUSG00000055177|Vega:OTTMUSG00000015717 +228765 Sdcbp2 MGI:MGI:2385156|Ensembl:ENSMUSG00000027456|Vega:OTTMUSG00000015866 +228767 Tmem74bos MGI:MGI:3039588 +228769 Psmf1 MGI:MGI:1346072|Ensembl:ENSMUSG00000032869|Vega:OTTMUSG00000015817 +228770 Rspo4 MGI:MGI:1924467|Ensembl:ENSMUSG00000032852|Vega:OTTMUSG00000015809 +228775 Trib3 MGI:MGI:1345675|Ensembl:ENSMUSG00000032715|Vega:OTTMUSG00000015851 +228777 Nrsn2 MGI:MGI:2684969|Ensembl:ENSMUSG00000059361|Vega:OTTMUSG00000015839 +228778 6820408C15Rik MGI:MGI:3045333|Ensembl:ENSMUSG00000032680|Vega:OTTMUSG00000015836 +228785 Mylk2 MGI:MGI:2139434|Ensembl:ENSMUSG00000027470|Vega:OTTMUSG00000015847 +228787 Xkr7 MGI:MGI:3526711|Ensembl:ENSMUSG00000042631|Vega:OTTMUSG00000015779 +228788 Ccm2l MGI:MGI:2385159|Ensembl:ENSMUSG00000027474|Vega:OTTMUSG00000015776 +228790 Asxl1 MGI:MGI:2684063|Ensembl:ENSMUSG00000042548|Vega:OTTMUSG00000019852 +228792 Dnmt3bos MGI:MGI:2685409 +228796 Bpifb6 MGI:MGI:2684965|Ensembl:ENSMUSG00000068009|Vega:OTTMUSG00000016851 +228801 Bpifb1 MGI:MGI:2137431|Ensembl:ENSMUSG00000027485|Vega:OTTMUSG00000015883 +228802 Bpifb5 MGI:MGI:2385160|Ensembl:ENSMUSG00000038572|Vega:OTTMUSG00000015884 +228807 Zfp341 MGI:MGI:2682937|Ensembl:ENSMUSG00000059842|Vega:OTTMUSG00000015920 +228812 Pigu MGI:MGI:3039607|Ensembl:ENSMUSG00000038383|Vega:OTTMUSG00000016004 +228829 Phf20 MGI:MGI:2444148|Ensembl:ENSMUSG00000038116|Vega:OTTMUSG00000016135 +228836 Dlgap4 MGI:MGI:2138865|Ensembl:ENSMUSG00000061689|Vega:OTTMUSG00000016033 +228839 Tgif2 MGI:MGI:1915299|Ensembl:ENSMUSG00000062175|Vega:OTTMUSG00000016034 +228846 D630003M21Rik MGI:MGI:3606579|Ensembl:ENSMUSG00000037813|Vega:OTTMUSG00000015939 +228850 Ralgapb MGI:MGI:2444531|Ensembl:ENSMUSG00000027652|Vega:OTTMUSG00000015940 +228852 Ppp1r16b MGI:MGI:2151841|Ensembl:ENSMUSG00000037754|Vega:OTTMUSG00000015931 +228858 Gdap1l1 MGI:MGI:2385163|Ensembl:ENSMUSG00000017943|Vega:OTTMUSG00000001073 +228859 Fitm2 MGI:MGI:2444508|Ensembl:ENSMUSG00000048486|Vega:OTTMUSG00000001072 +228866 Pcif1 MGI:MGI:2443858|Ensembl:ENSMUSG00000039849|Vega:OTTMUSG00000019973 +228869 Ncoa5 MGI:MGI:2385165|Ensembl:ENSMUSG00000039804|Vega:OTTMUSG00000001105 +228875 Slc35c2 MGI:MGI:2385166|Ensembl:ENSMUSG00000017664|Vega:OTTMUSG00000001172 +228876 Zfp334 MGI:MGI:2388656|Ensembl:ENSMUSG00000017667|Vega:OTTMUSG00000001117 +228880 Zmynd8 MGI:MGI:1918025|Ensembl:ENSMUSG00000039671|Vega:OTTMUSG00000001126 +228889 Ddx27 MGI:MGI:2385884|Ensembl:ENSMUSG00000017999|Vega:OTTMUSG00000001151 +228911 Tshz2 MGI:MGI:2153084|Ensembl:ENSMUSG00000047907|Vega:OTTMUSG00000016080 +228913 Zfp217 MGI:MGI:2685408|Ensembl:ENSMUSG00000052056|Vega:OTTMUSG00000016078 +228916 Gm14269 MGI:MGI:3650060 +228942 Cbln4 MGI:MGI:2154433|Ensembl:ENSMUSG00000067578|Vega:OTTMUSG00000016162 +228960 Stx16 MGI:MGI:1923396|Ensembl:ENSMUSG00000027522|Vega:OTTMUSG00000016368 +228961 Npepl1 MGI:MGI:2448523|Ensembl:ENSMUSG00000039263|Vega:OTTMUSG00000016370 +228966 Ppp1r3d MGI:MGI:1917664|Ensembl:ENSMUSG00000049999|Vega:OTTMUSG00000016352 +228980 Taf4 MGI:MGI:2152346|Ensembl:ENSMUSG00000039117|Vega:OTTMUSG00000016232 +228983 Osbpl2 MGI:MGI:2442832|Ensembl:ENSMUSG00000039050|Vega:OTTMUSG00000016257 +228993 Slc17a9 MGI:MGI:1919107|Ensembl:ENSMUSG00000023393|Vega:OTTMUSG00000016390 +228994 Ythdf1 MGI:MGI:1917431|Ensembl:ENSMUSG00000038848|Vega:OTTMUSG00000016403 +228998 Arfgap1 MGI:MGI:2183559|Ensembl:ENSMUSG00000027575|Vega:OTTMUSG00000016397 +229003 Helz2 MGI:MGI:2385169|Ensembl:ENSMUSG00000027580|Vega:OTTMUSG00000016565 +229004 Gmeb2 MGI:MGI:2652836|Ensembl:ENSMUSG00000038705|Vega:OTTMUSG00000016562 +229007 Zgpat MGI:MGI:2449939|Ensembl:ENSMUSG00000027582|Vega:OTTMUSG00000016650 +229011 Samd10 MGI:MGI:2443872|Ensembl:ENSMUSG00000038605|Vega:OTTMUSG00000016736 +229055 Zbtb10 MGI:MGI:2139883|Ensembl:ENSMUSG00000069114|Vega:OTTMUSG00000033722 +229096 Ythdf3 MGI:MGI:1918850|Ensembl:ENSMUSG00000047213|Vega:OTTMUSG00000051093 +229152 Gm4855 MGI:MGI:3648363 +229211 Acad9 MGI:MGI:1914272|Ensembl:ENSMUSG00000027710|Vega:OTTMUSG00000023529 +229214 Qrfpr MGI:MGI:2677633|Ensembl:ENSMUSG00000058400|Vega:OTTMUSG00000026506 +229227 4932438A13Rik MGI:MGI:2444631|Ensembl:ENSMUSG00000037270|Vega:OTTMUSG00000006539 +229228 Nudt6 MGI:MGI:2387618|Ensembl:ENSMUSG00000050174|Vega:OTTMUSG00000007435 +229277 Stoml3 MGI:MGI:2388072|Ensembl:ENSMUSG00000027744|Vega:OTTMUSG00000026678 +229279 Hnrnpa3 MGI:MGI:1917171|Ensembl:ENSMUSG00000059005|Vega:OTTMUSG00000013249 +229285 Spg20 MGI:MGI:2139806|Ensembl:ENSMUSG00000036580|Vega:OTTMUSG00000026686 +229302 Tm4sf4 MGI:MGI:2385173|Ensembl:ENSMUSG00000027801|Vega:OTTMUSG00000026676 +229317 Eif2a MGI:MGI:1098684|Ensembl:ENSMUSG00000027810|Vega:OTTMUSG00000029357 +229320 Clrn1 MGI:MGI:2388124|Ensembl:ENSMUSG00000043850|Vega:OTTMUSG00000031611 +229323 Gpr171 MGI:MGI:2442043|Ensembl:ENSMUSG00000050075|Vega:OTTMUSG00000052446 +229330 Gm4856 MGI:MGI:3644725 +229333 C130079G13Rik MGI:MGI:3028051|Ensembl:ENSMUSG00000036951|Vega:OTTMUSG00000052112 +229357 Gpr149 MGI:MGI:2443628|Ensembl:ENSMUSG00000043441|Vega:OTTMUSG00000026584 +229363 Gmps MGI:MGI:2448526|Ensembl:ENSMUSG00000027823|Vega:OTTMUSG00000031018 +229389 Otol1 MGI:MGI:2685260|Ensembl:ENSMUSG00000027788|Vega:OTTMUSG00000026600 +229443 Gm4857 MGI:MGI:3645075 +229445 Ctso MGI:MGI:2139628|Ensembl:ENSMUSG00000028015|Vega:OTTMUSG00000026582 +229459 Dchs2 MGI:MGI:2685263 +229473 Tmem131l MGI:MGI:2443399|Ensembl:ENSMUSG00000033767|Vega:OTTMUSG00000051568 +229474 Fhdc1 MGI:MGI:2684972|Ensembl:ENSMUSG00000041842|Vega:OTTMUSG00000023128 +229487 Gatb MGI:MGI:2442496|Ensembl:ENSMUSG00000028085|Vega:OTTMUSG00000023360 +229488 Fam160a1 MGI:MGI:2444746|Ensembl:ENSMUSG00000051000|Vega:OTTMUSG00000026671 +229499 Fcrl1 MGI:MGI:2442862|Ensembl:ENSMUSG00000059994|Vega:OTTMUSG00000051777 +229503 Rrnad1 MGI:MGI:2387197|Ensembl:ENSMUSG00000004896|Vega:OTTMUSG00000027514 +229504 Isg20l2 MGI:MGI:2140076|Ensembl:ENSMUSG00000048039|Vega:OTTMUSG00000032741 +229512 Smg5 MGI:MGI:2447364|Ensembl:ENSMUSG00000001415|Vega:OTTMUSG00000052142 +229517 Slc25a44 MGI:MGI:2444391|Ensembl:ENSMUSG00000050144|Vega:OTTMUSG00000052157 +229521 Syt11 MGI:MGI:1859547|Ensembl:ENSMUSG00000068923|Vega:OTTMUSG00000022625 +229524 Msto1 MGI:MGI:2385175|Ensembl:ENSMUSG00000068922|Vega:OTTMUSG00000023693 +229534 Pbxip1 MGI:MGI:2441670|Ensembl:ENSMUSG00000042613|Vega:OTTMUSG00000022073 +229541 Dennd4b MGI:MGI:2446201|Ensembl:ENSMUSG00000042404|Vega:OTTMUSG00000033352 +229542 Gatad2b MGI:MGI:2443225|Ensembl:ENSMUSG00000042390|Vega:OTTMUSG00000052659 +229543 Ints3 MGI:MGI:2140050|Ensembl:ENSMUSG00000027933|Vega:OTTMUSG00000052748 +229550 9130204L05Rik MGI:MGI:2684973|Ensembl:ENSMUSG00000091175|Vega:OTTMUSG00000052656 +229562 Sprr4 MGI:MGI:2654508|Ensembl:ENSMUSG00000045566|Vega:OTTMUSG00000051841 +229571 Gm4858 MGI:MGI:3645677|Ensembl:ENSMUSG00000096879|Vega:OTTMUSG00000051910 +229574 Flg2 MGI:MGI:3645678 +229584 Pogz MGI:MGI:2442117|Ensembl:ENSMUSG00000038902|Vega:OTTMUSG00000019666 +229588 Gm128 MGI:MGI:2684974|Ensembl:ENSMUSG00000068860|Vega:OTTMUSG00000022032 +229589 Prune1 MGI:MGI:1925152|Ensembl:ENSMUSG00000015711|Vega:OTTMUSG00000022362 +229593 Golph3l MGI:MGI:1917129|Ensembl:ENSMUSG00000046519|Vega:OTTMUSG00000042031 +229595 Adamtsl4 MGI:MGI:2389008|Ensembl:ENSMUSG00000015850|Vega:OTTMUSG00000027489 +229599 Ciart MGI:MGI:2684975|Ensembl:ENSMUSG00000038550|Vega:OTTMUSG00000030556 +229600 BC028528 MGI:MGI:2385885|Ensembl:ENSMUSG00000038543|Vega:OTTMUSG00000022035 +229603 Otud7b MGI:MGI:2654703|Ensembl:ENSMUSG00000038495|Vega:OTTMUSG00000021893 +229613 6330549D23Rik MGI:MGI:2442586|Ensembl:ENSMUSG00000045327 +229615 Pias3 MGI:MGI:1913126|Ensembl:ENSMUSG00000028101|Vega:OTTMUSG00000034169 +229644 Trim45 MGI:MGI:1918187|Ensembl:ENSMUSG00000033233|Vega:OTTMUSG00000007079 +229658 Vangl1 MGI:MGI:2159344|Ensembl:ENSMUSG00000027860|Vega:OTTMUSG00000031053 +229663 Csde1 MGI:MGI:92356|Ensembl:ENSMUSG00000068823|Vega:OTTMUSG00000054929 +229665 Ampd1 MGI:MGI:88015|Ensembl:ENSMUSG00000070385|Vega:OTTMUSG00000030299 +229672 Bcl2l15 MGI:MGI:2685412|Ensembl:ENSMUSG00000044165|Vega:OTTMUSG00000022064 +229675 Rsbn1 MGI:MGI:2444993|Ensembl:ENSMUSG00000044098|Vega:OTTMUSG00000024243 +229681 St7l MGI:MGI:2386964|Ensembl:ENSMUSG00000045576|Vega:OTTMUSG00000022244 +229687 Chil5 MGI:MGI:2676649|Ensembl:ENSMUSG00000043873|Vega:OTTMUSG00000036836 +229688 Chil6 MGI:MGI:2682303|Ensembl:ENSMUSG00000027902|Vega:OTTMUSG00000052901 +229694 AI504432 MGI:MGI:2139742|Ensembl:ENSMUSG00000056145 +229697 Cym MGI:MGI:2684977|Ensembl:ENSMUSG00000046213|Vega:OTTMUSG00000033772 +229699 Slc16a4 MGI:MGI:2385183|Ensembl:ENSMUSG00000027896|Vega:OTTMUSG00000024152 +229700 Rbm15 MGI:MGI:2443205|Ensembl:ENSMUSG00000048109|Vega:OTTMUSG00000052948 +229706 Slc6a17 MGI:MGI:2442535|Ensembl:ENSMUSG00000027894|Vega:OTTMUSG00000036634 +229707 Strip1 MGI:MGI:2443884|Ensembl:ENSMUSG00000014601|Vega:OTTMUSG00000053013 +229709 Ahcyl1 MGI:MGI:2385184|Ensembl:ENSMUSG00000027893|Vega:OTTMUSG00000029454 +229714 Gpr61 MGI:MGI:2441719|Ensembl:ENSMUSG00000046793|Vega:OTTMUSG00000007190 +229715 Amigo1 MGI:MGI:2653612|Ensembl:ENSMUSG00000050947|Vega:OTTMUSG00000007182 +229722 5330417C22Rik MGI:MGI:1923930|Ensembl:ENSMUSG00000040412|Vega:OTTMUSG00000007254 +229725 Clcc1 MGI:MGI:2385186|Ensembl:ENSMUSG00000027884|Vega:OTTMUSG00000007251 +229731 Slc25a24 MGI:MGI:1917160|Ensembl:ENSMUSG00000040322|Vega:OTTMUSG00000007353 +229746 Gm4859 MGI:MGI:3646906 +229759 Olfm3 MGI:MGI:2387329|Ensembl:ENSMUSG00000027965|Vega:OTTMUSG00000026597 +229776 Cdc14a MGI:MGI:2442676|Ensembl:ENSMUSG00000033502|Vega:OTTMUSG00000029379 +229780 Trmt13 MGI:MGI:1925219|Ensembl:ENSMUSG00000033439|Vega:OTTMUSG00000054476 +229782 Slc35a3 MGI:MGI:1917648|Ensembl:ENSMUSG00000027957|Vega:OTTMUSG00000029522 +229791 Plppr4 MGI:MGI:106530|Ensembl:ENSMUSG00000044667|Vega:OTTMUSG00000023917 +229801 Tram1l1 MGI:MGI:2443503|Ensembl:ENSMUSG00000044528|Vega:OTTMUSG00000052583 +229837 Gm4860 MGI:MGI:3647155 +229841 Cenpe MGI:MGI:1098230|Ensembl:ENSMUSG00000045328|Vega:OTTMUSG00000054878 +229861 Gm567 MGI:MGI:2685413 +229862 Gm4861 MGI:MGI:3643777|Ensembl:ENSMUSG00000055138 +229877 Rap1gds1 MGI:MGI:2385189|Ensembl:ENSMUSG00000028149|Vega:OTTMUSG00000052979 +229879 Gm4862 MGI:MGI:3646671 +229883 Gm4863 MGI:MGI:3643064 +229898 Gbp5 MGI:MGI:2429943|Ensembl:ENSMUSG00000105504|Vega:OTTMUSG00000053926 +229900 Gbp7 MGI:MGI:2444421|Ensembl:ENSMUSG00000040253|Vega:OTTMUSG00000053927 +229905 Kyat3 MGI:MGI:2677849|Ensembl:ENSMUSG00000040213|Vega:OTTMUSG00000023409 +229906 Gtf2b MGI:MGI:2385191|Ensembl:ENSMUSG00000028271|Vega:OTTMUSG00000054080 +229927 Clca3b MGI:MGI:2181989|Ensembl:ENSMUSG00000037033|Vega:OTTMUSG00000030497 +229933 Clca2 MGI:MGI:2139758|Ensembl:ENSMUSG00000036960|Vega:OTTMUSG00000055186 +229937 Znhit6 MGI:MGI:1916996|Ensembl:ENSMUSG00000074182|Vega:OTTMUSG00000055190 +229949 Ak5 MGI:MGI:2677491|Ensembl:ENSMUSG00000039058|Vega:OTTMUSG00000053834 +230010 Gm11839 MGI:MGI:3651162 +230025 Prdm13 MGI:MGI:2448528|Ensembl:ENSMUSG00000040478|Vega:OTTMUSG00000004716 +230027 Coq3 MGI:MGI:101813|Ensembl:ENSMUSG00000028247|Vega:OTTMUSG00000004763 +230044 Gm11907 MGI:MGI:3650140 +230073 Ddx58 MGI:MGI:2442858|Ensembl:ENSMUSG00000040296|Vega:OTTMUSG00000006554 +230075 Ndufb6 MGI:MGI:2684983|Ensembl:ENSMUSG00000071014|Vega:OTTMUSG00000006581 +230082 Nol6 MGI:MGI:2140151|Ensembl:ENSMUSG00000028430|Vega:OTTMUSG00000006643 +230085 Phf24 MGI:MGI:2140712|Ensembl:ENSMUSG00000036062|Vega:OTTMUSG00000006615 +230088 Fam214b MGI:MGI:2441854|Ensembl:ENSMUSG00000036002|Vega:OTTMUSG00000006708 +230098 Arhgef39 MGI:MGI:3036286|Ensembl:ENSMUSG00000051517|Vega:OTTMUSG00000006925 +230099 Car9 MGI:MGI:2447188|Ensembl:ENSMUSG00000028463|Vega:OTTMUSG00000006931 +230101 Gba2 MGI:MGI:2654325|Ensembl:ENSMUSG00000028467|Vega:OTTMUSG00000006971 +230103 Npr2 MGI:MGI:97372|Ensembl:ENSMUSG00000028469|Vega:OTTMUSG00000007021 +230119 Zbtb5 MGI:MGI:1924601|Ensembl:ENSMUSG00000049657|Vega:OTTMUSG00000007325 +230125 Slc25a51 MGI:MGI:2684984|Ensembl:ENSMUSG00000045973|Vega:OTTMUSG00000006722 +230126 Shb MGI:MGI:98294|Ensembl:ENSMUSG00000044813|Vega:OTTMUSG00000006723 +230143 Gm568 MGI:MGI:2685414 +230145 Galnt12 MGI:MGI:2444664|Ensembl:ENSMUSG00000039774|Vega:OTTMUSG00000006777 +230157 Tmeff1 MGI:MGI:1926810|Ensembl:ENSMUSG00000028347|Vega:OTTMUSG00000006852 +230161 Acnat1 MGI:MGI:2140197|Ensembl:ENSMUSG00000070985|Vega:OTTMUSG00000008317 +230162 Zfp189 MGI:MGI:2444707|Ensembl:ENSMUSG00000039634|Vega:OTTMUSG00000008316 +230163 Aldob MGI:MGI:87995|Ensembl:ENSMUSG00000028307|Vega:OTTMUSG00000008318 +230233 Ikbkap MGI:MGI:1914544|Ensembl:ENSMUSG00000028431|Vega:OTTMUSG00000007272 +230234 Fam206a MGI:MGI:2677850|Ensembl:ENSMUSG00000038827|Vega:OTTMUSG00000007319 +230235 Frrs1l MGI:MGI:2442704|Ensembl:ENSMUSG00000045589|Vega:OTTMUSG00000007318 +230249 AI314180 MGI:MGI:2140220|Ensembl:ENSMUSG00000050812|Vega:OTTMUSG00000007619 +230257 Ptbp3 MGI:MGI:1923334|Ensembl:ENSMUSG00000028382|Vega:OTTMUSG00000007334 +230259 E130308A19Rik MGI:MGI:2442164|Ensembl:ENSMUSG00000045071|Vega:OTTMUSG00000007411 +230279 Tmem268 MGI:MGI:1913920|Ensembl:ENSMUSG00000045917|Vega:OTTMUSG00000000250 +230316 Megf9 MGI:MGI:1918264|Ensembl:ENSMUSG00000039270|Vega:OTTMUSG00000000314 +230376 Haus6 MGI:MGI:1923389|Ensembl:ENSMUSG00000038047|Vega:OTTMUSG00000007451 +230379 Acer2 MGI:MGI:1920932|Ensembl:ENSMUSG00000038007|Vega:OTTMUSG00000007779 +230393 Focad MGI:MGI:2676921|Ensembl:ENSMUSG00000038368|Vega:OTTMUSG00000019865 +230396 Ifna13 MGI:MGI:2667155|Ensembl:ENSMUSG00000063376|Vega:OTTMUSG00000011277 +230398 Ifna16 MGI:MGI:3649260|Ensembl:ENSMUSG00000078355|Vega:OTTMUSG00000011275 +230405 Ifne MGI:MGI:2667156|Ensembl:ENSMUSG00000045364|Vega:OTTMUSG00000007692 +230451 Junos MGI:MGI:2652837 +230459 Cyp2j13 MGI:MGI:2385197|Ensembl:ENSMUSG00000028571|Vega:OTTMUSG00000007936 +230484 Usp1 MGI:MGI:2385198|Ensembl:ENSMUSG00000028560|Vega:OTTMUSG00000008702 +230500 Efcab7 MGI:MGI:2385199|Ensembl:ENSMUSG00000073791 +230514 Leprot MGI:MGI:2687005|Ensembl:ENSMUSG00000035212|Vega:OTTMUSG00000008452 +230558 C8a MGI:MGI:2668347|Ensembl:ENSMUSG00000035031|Vega:OTTMUSG00000008116 +230576 Ttc22 MGI:MGI:3045307|Ensembl:ENSMUSG00000034919|Vega:OTTMUSG00000008160 +230577 Pars2 MGI:MGI:2386296|Ensembl:ENSMUSG00000043572|Vega:OTTMUSG00000008162 +230579 Fam151a MGI:MGI:2657115|Ensembl:ENSMUSG00000034871|Vega:OTTMUSG00000008202 +230582 Cyb5rl MGI:MGI:1919657|Ensembl:ENSMUSG00000028621|Vega:OTTMUSG00000008414 +230584 Yipf1 MGI:MGI:1915532|Ensembl:ENSMUSG00000057375|Vega:OTTMUSG00000008802 +230587 Glis1 MGI:MGI:2386723|Ensembl:ENSMUSG00000034762|Vega:OTTMUSG00000008920 +230590 Zyg11a MGI:MGI:2446208|Ensembl:ENSMUSG00000034645|Vega:OTTMUSG00000008237 +230594 Zcchc11 MGI:MGI:2445126|Ensembl:ENSMUSG00000034610|Vega:OTTMUSG00000008242 +230596 Prpf38a MGI:MGI:1916962|Ensembl:ENSMUSG00000063800|Vega:OTTMUSG00000008232 +230597 Zfyve9 MGI:MGI:2652838|Ensembl:ENSMUSG00000034557|Vega:OTTMUSG00000008247 +230598 Nrd1 MGI:MGI:1201386|Ensembl:ENSMUSG00000053510|Vega:OTTMUSG00000008296 +230603 Ttc39a MGI:MGI:2444350|Ensembl:ENSMUSG00000028555|Vega:OTTMUSG00000008295 +230612 Slc5a9 MGI:MGI:2140201|Ensembl:ENSMUSG00000028544|Vega:OTTMUSG00000009474 +230613 Skint10 MGI:MGI:2685416|Ensembl:ENSMUSG00000048766|Vega:OTTMUSG00000008539 +230622 Skint6 MGI:MGI:3649262|Ensembl:ENSMUSG00000087194|Vega:OTTMUSG00000008519 +230623 Skint11 MGI:MGI:2685415|Ensembl:ENSMUSG00000057977|Vega:OTTMUSG00000008559 +230639 Cyp4a29 MGI:MGI:3717143|Ensembl:ENSMUSG00000083138|Vega:OTTMUSG00000008612 +230641 Gm12833 MGI:MGI:3651919 +230648 Efcab14 MGI:MGI:2442397|Ensembl:ENSMUSG00000034210|Vega:OTTMUSG00000008688 +230649 Atpaf1 MGI:MGI:2180560|Ensembl:ENSMUSG00000028710|Vega:OTTMUSG00000008684 +230654 Lrrc41 MGI:MGI:2441984|Ensembl:ENSMUSG00000028703|Vega:OTTMUSG00000008751 +230657 Tmem69 MGI:MGI:3045357|Ensembl:ENSMUSG00000055900|Vega:OTTMUSG00000009412 +230661 Tesk2 MGI:MGI:2385204|Ensembl:ENSMUSG00000033985|Vega:OTTMUSG00000009675 +230664 Best4-ps MGI:MGI:3663793 +230673 Ipo13 MGI:MGI:2385205|Ensembl:ENSMUSG00000033365|Vega:OTTMUSG00000008657 +230674 Kdm4a MGI:MGI:2446210|Ensembl:ENSMUSG00000033326|Vega:OTTMUSG00000008717 +230676 Szt2 MGI:MGI:3033336|Ensembl:ENSMUSG00000033253|Vega:OTTMUSG00000008774 +230678 Tmem125 MGI:MGI:1923409|Ensembl:ENSMUSG00000050854|Vega:OTTMUSG00000008794 +230696 AU022252 MGI:MGI:2140466|Ensembl:ENSMUSG00000078584|Vega:OTTMUSG00000008957 +230700 Foxj3 MGI:MGI:2443432|Ensembl:ENSMUSG00000032998|Vega:OTTMUSG00000009437 +230709 Zmpste24 MGI:MGI:1890508|Ensembl:ENSMUSG00000043207|Vega:OTTMUSG00000008909 +230718 Nt5c1a MGI:MGI:2155700|Ensembl:ENSMUSG00000054958|Vega:OTTMUSG00000008973 +230721 Pabpc4 MGI:MGI:2385206|Ensembl:ENSMUSG00000011257|Vega:OTTMUSG00000008978 +230726 Rhbdl2 MGI:MGI:3608413|Ensembl:ENSMUSG00000043333|Vega:OTTMUSG00000008993 +230734 Yrdc MGI:MGI:2387201|Ensembl:ENSMUSG00000028889|Vega:OTTMUSG00000009199 +230735 Epha10 MGI:MGI:3586824|Ensembl:ENSMUSG00000028876|Vega:OTTMUSG00000009202 +230737 Gnl2 MGI:MGI:2385207|Ensembl:ENSMUSG00000028869|Vega:OTTMUSG00000009250 +230738 Zc3h12a MGI:MGI:2385891|Ensembl:ENSMUSG00000042677|Vega:OTTMUSG00000009246 +230751 Oscp1 MGI:MGI:1916308|Ensembl:ENSMUSG00000042616|Vega:OTTMUSG00000009294 +230752 Eva1b MGI:MGI:1922063|Ensembl:ENSMUSG00000050212|Vega:OTTMUSG00000009357 +230753 Thrap3 MGI:MGI:2442637|Ensembl:ENSMUSG00000043962|Vega:OTTMUSG00000009350 +230757 5730409E04Rik MGI:MGI:3609248|Ensembl:ENSMUSG00000073755|Vega:OTTMUSG00000009277 +230761 Zfp362 MGI:MGI:2652839|Ensembl:ENSMUSG00000028799|Vega:OTTMUSG00000009542 +230765 Gm4864 MGI:MGI:3643492 +230766 Fam167b MGI:MGI:2668032|Ensembl:ENSMUSG00000050493|Vega:OTTMUSG00000009513 +230767 Iqcc MGI:MGI:2446212|Ensembl:ENSMUSG00000040795|Vega:OTTMUSG00000009512 +230770 Tmem39b MGI:MGI:2682939|Ensembl:ENSMUSG00000053730|Vega:OTTMUSG00000009517 +230775 Adgrb2 MGI:MGI:2451244|Ensembl:ENSMUSG00000028782|Vega:OTTMUSG00000009519 +230777 Hcrtr1 MGI:MGI:2385650|Ensembl:ENSMUSG00000028778|Vega:OTTMUSG00000009509 +230779 Serinc2 MGI:MGI:1919132|Ensembl:ENSMUSG00000023232|Vega:OTTMUSG00000009563 +230784 Sesn2 MGI:MGI:2651874|Ensembl:ENSMUSG00000028893|Vega:OTTMUSG00000009672 +230787 Themis2 MGI:MGI:2446213|Ensembl:ENSMUSG00000037731|Vega:OTTMUSG00000009993 +230789 Fam76a MGI:MGI:2385211|Ensembl:ENSMUSG00000028878|Vega:OTTMUSG00000010098 +230793 Ahdc1 MGI:MGI:2444218|Ensembl:ENSMUSG00000037692|Vega:OTTMUSG00000010097 +230796 Wdtc1 MGI:MGI:2685541|Ensembl:ENSMUSG00000037622|Vega:OTTMUSG00000011148 +230801 Pigv MGI:MGI:2442480|Ensembl:ENSMUSG00000043257|Vega:OTTMUSG00000010997 +230806 Crybg2 MGI:MGI:1334463|Ensembl:ENSMUSG00000012123|Vega:OTTMUSG00000010218 +230809 Pdik1l MGI:MGI:2385213|Ensembl:ENSMUSG00000050890|Vega:OTTMUSG00000010605 +230810 Slc30a2 MGI:MGI:106637|Ensembl:ENSMUSG00000028836|Vega:OTTMUSG00000010829 +230815 Man1c1 MGI:MGI:2446214|Ensembl:ENSMUSG00000037306|Vega:OTTMUSG00000011212 +230822 Ncmap MGI:MGI:2444888|Ensembl:ENSMUSG00000043924|Vega:OTTMUSG00000009728 +230824 Grhl3 MGI:MGI:2655333|Ensembl:ENSMUSG00000037188|Vega:OTTMUSG00000009727 +230828 Il22ra1 MGI:MGI:2663588|Ensembl:ENSMUSG00000037157|Vega:OTTMUSG00000009729 +230837 Asap3 MGI:MGI:2684986|Ensembl:ENSMUSG00000036995|Vega:OTTMUSG00000009863 +230848 Zbtb40 MGI:MGI:2682254|Ensembl:ENSMUSG00000060862|Vega:OTTMUSG00000009824 +230857 Ece1 MGI:MGI:1101357|Ensembl:ENSMUSG00000057530|Vega:OTTMUSG00000009809 +230861 Eif4g3 MGI:MGI:1923935|Ensembl:ENSMUSG00000028760|Vega:OTTMUSG00000009883 +230863 Sh2d5 MGI:MGI:2446215|Ensembl:ENSMUSG00000045349|Vega:OTTMUSG00000009973 +230866 Emc1 MGI:MGI:2443696|Ensembl:ENSMUSG00000078517|Vega:OTTMUSG00000009955 +230868 Igsf21 MGI:MGI:2681842|Ensembl:ENSMUSG00000040972|Vega:OTTMUSG00000010057 +230872 Crocc MGI:MGI:3529431|Ensembl:ENSMUSG00000040860|Vega:OTTMUSG00000010088 +230883 Aadacl3 MGI:MGI:2685281|Ensembl:ENSMUSG00000078507|Vega:OTTMUSG00000010538 +230890 Gm436 MGI:MGI:2685282|Ensembl:ENSMUSG00000078505|Vega:OTTMUSG00000020306 +230895 Vps13d MGI:MGI:2448530|Ensembl:ENSMUSG00000020220|Vega:OTTMUSG00000010745 +230899 Nppa MGI:MGI:97367|Ensembl:ENSMUSG00000041616|Vega:OTTMUSG00000010192 +230903 Fbxo44 MGI:MGI:1354744|Ensembl:ENSMUSG00000029001|Vega:OTTMUSG00000010932 +230904 Fbxo2 MGI:MGI:2446216|Ensembl:ENSMUSG00000041556|Vega:OTTMUSG00000010936 +230908 Tardbp MGI:MGI:2387629|Ensembl:ENSMUSG00000041459|Vega:OTTMUSG00000010947 +230909 Gm572 MGI:MGI:2685418|Ensembl:ENSMUSG00000070577|Vega:OTTMUSG00000010944 +230917 Tmem201 MGI:MGI:1196277|Ensembl:ENSMUSG00000044700|Vega:OTTMUSG00000010276 +230935 Dnajc11 MGI:MGI:2443386|Ensembl:ENSMUSG00000039768|Vega:OTTMUSG00000010358 +230936 Phf13 MGI:MGI:2446217|Ensembl:ENSMUSG00000047777|Vega:OTTMUSG00000010357 +230959 Ajap1 MGI:MGI:2685419|Ensembl:ENSMUSG00000039546|Vega:OTTMUSG00000010367 +230967 Cep104 MGI:MGI:2687282|Ensembl:ENSMUSG00000039523|Vega:OTTMUSG00000010498 +230971 Megf6 MGI:MGI:1919351|Ensembl:ENSMUSG00000057751|Vega:OTTMUSG00000010501 +230972 Arhgef16 MGI:MGI:2446219|Ensembl:ENSMUSG00000029032|Vega:OTTMUSG00000010513 +230979 Tnfrsf14 MGI:MGI:2675303|Ensembl:ENSMUSG00000042333|Vega:OTTMUSG00000010461 +230991 Fndc10 MGI:MGI:2444790|Ensembl:ENSMUSG00000074738|Vega:OTTMUSG00000010729 +230996 9430015G10Rik MGI:MGI:2444364|Ensembl:ENSMUSG00000059939|Vega:OTTMUSG00000011081 +231002 Plekhn1 MGI:MGI:2387630|Ensembl:ENSMUSG00000078485 +231003 Klhl17 MGI:MGI:2678948|Ensembl:ENSMUSG00000078485 +231004 Samd11 MGI:MGI:2446220|Ensembl:ENSMUSG00000096351 +231014 9330182L06Rik MGI:MGI:2443264|Ensembl:ENSMUSG00000056004|Vega:OTTMUSG00000025805 +231042 Nupl2 MGI:MGI:2387631|Ensembl:ENSMUSG00000048439|Vega:OTTMUSG00000024106 +231044 Gbx1 MGI:MGI:95667|Ensembl:ENSMUSG00000067724|Vega:OTTMUSG00000024202 +231045 4931409K22Rik MGI:MGI:3045319|Ensembl:ENSMUSG00000038199|Vega:OTTMUSG00000053697 +231050 Galnt11 MGI:MGI:2444392|Ensembl:ENSMUSG00000038072|Vega:OTTMUSG00000024235 +231051 Kmt2c MGI:MGI:2444959|Ensembl:ENSMUSG00000038056|Vega:OTTMUSG00000037000 +231069 Gm4865 MGI:MGI:3647137 +231070 Insig1 MGI:MGI:1916289|Ensembl:ENSMUSG00000045294|Vega:OTTMUSG00000042425 +231086 Hadhb MGI:MGI:2136381|Ensembl:ENSMUSG00000059447|Vega:OTTMUSG00000024744 +231093 Agbl5 MGI:MGI:2441745|Ensembl:ENSMUSG00000029165|Vega:OTTMUSG00000022346 +231098 Dnajc5g MGI:MGI:3045263|Ensembl:ENSMUSG00000053856|Vega:OTTMUSG00000047923 +231103 Gckr MGI:MGI:1096345|Ensembl:ENSMUSG00000059434|Vega:OTTMUSG00000055211 +231123 Haus3 MGI:MGI:2387633|Ensembl:ENSMUSG00000079555|Vega:OTTMUSG00000055716 +231125 Zfyve28 MGI:MGI:2684992|Ensembl:ENSMUSG00000037224|Vega:OTTMUSG00000023090 +231128 Fam193a MGI:MGI:2447768|Ensembl:ENSMUSG00000037210|Vega:OTTMUSG00000042593 +231130 Tnip2 MGI:MGI:2386643|Ensembl:ENSMUSG00000059866|Vega:OTTMUSG00000023093 +231134 Dok7 MGI:MGI:3584043|Ensembl:ENSMUSG00000044716|Vega:OTTMUSG00000022794 +231147 Sh3tc1 MGI:MGI:2678949|Ensembl:ENSMUSG00000036553|Vega:OTTMUSG00000024850 +231148 Ablim2 MGI:MGI:2385758|Ensembl:ENSMUSG00000029095|Vega:OTTMUSG00000024832 +231151 Tada2b MGI:MGI:3035274|Ensembl:ENSMUSG00000029196|Vega:OTTMUSG00000028005 +231162 Cytl1 MGI:MGI:2684993|Ensembl:ENSMUSG00000062329|Vega:OTTMUSG00000056099 +231201 AF366264 MGI:MGI:2667157|Ensembl:ENSMUSG00000057116|Vega:OTTMUSG00000060788 +231207 Cpeb2 MGI:MGI:2442640|Ensembl:ENSMUSG00000039782|Vega:OTTMUSG00000023193 +231214 Cc2d2a MGI:MGI:1924487|Ensembl:ENSMUSG00000039765|Vega:OTTMUSG00000018224 +231225 Tapt1 MGI:MGI:2683537|Ensembl:ENSMUSG00000046985|Vega:OTTMUSG00000053809 +231238 Sel1l3 MGI:MGI:1916941|Ensembl:ENSMUSG00000029189|Vega:OTTMUSG00000054611 +231252 Chrna9 MGI:MGI:1202403|Ensembl:ENSMUSG00000029205|Vega:OTTMUSG00000022200 +231253 9130230L23Rik MGI:MGI:3041166|Ensembl:ENSMUSG00000054598|Vega:OTTMUSG00000022224 +231279 Guf1 MGI:MGI:2140726|Ensembl:ENSMUSG00000029208|Vega:OTTMUSG00000027761 +231287 Atp10d MGI:MGI:2450125|Ensembl:ENSMUSG00000046808|Vega:OTTMUSG00000022559 +231290 Slc10a4 MGI:MGI:3606480|Ensembl:ENSMUSG00000029219|Vega:OTTMUSG00000026748 +231293 Cwh43 MGI:MGI:2444131|Ensembl:ENSMUSG00000029154|Vega:OTTMUSG00000024904 +231296 Lrrc66 MGI:MGI:2387634|Ensembl:ENSMUSG00000067206|Vega:OTTMUSG00000026766 +231326 Aasdh MGI:MGI:2442517|Ensembl:ENSMUSG00000055923|Vega:OTTMUSG00000026517 +231327 Ppat MGI:MGI:2387203|Ensembl:ENSMUSG00000029246|Vega:OTTMUSG00000026529 +231329 Polr2b MGI:MGI:2388280|Ensembl:ENSMUSG00000029250|Vega:OTTMUSG00000026994 +231332 Pea15b MGI:MGI:3525016 +231368 Gm4866 MGI:MGI:3646530 +231380 Uba6 MGI:MGI:1913894|Ensembl:ENSMUSG00000035898|Vega:OTTMUSG00000025609 +231382 Tmprss11d MGI:MGI:2385221|Ensembl:ENSMUSG00000061259|Vega:OTTMUSG00000028240 +231386 Ythdc1 MGI:MGI:2443713|Ensembl:ENSMUSG00000035851|Vega:OTTMUSG00000028216 +231396 Ugt2b36 MGI:MGI:3576103|Ensembl:ENSMUSG00000070704|Vega:OTTMUSG00000026779 +231413 Grsf1 MGI:MGI:106479|Ensembl:ENSMUSG00000044221|Vega:OTTMUSG00000025237 +231430 Cox18 MGI:MGI:2448532|Ensembl:ENSMUSG00000035505|Vega:OTTMUSG00000027846 +231440 Parm1 MGI:MGI:2443349|Ensembl:ENSMUSG00000034981|Vega:OTTMUSG00000035368 +231452 Sdad1 MGI:MGI:2140779|Ensembl:ENSMUSG00000029415|Vega:OTTMUSG00000055601 +231464 Cnot6l MGI:MGI:2443154|Ensembl:ENSMUSG00000034724|Vega:OTTMUSG00000026588 +231470 Fras1 MGI:MGI:2385368|Ensembl:ENSMUSG00000034687|Vega:OTTMUSG00000053289 +231474 Paqr3 MGI:MGI:2679683|Ensembl:ENSMUSG00000055725|Vega:OTTMUSG00000023913 +231503 Tmem150c MGI:MGI:3041258|Ensembl:ENSMUSG00000050640|Vega:OTTMUSG00000026818 +231506 Lin54 MGI:MGI:2140902|Ensembl:ENSMUSG00000035310|Vega:OTTMUSG00000033912 +231507 Plac8 MGI:MGI:2445289|Ensembl:ENSMUSG00000029322|Vega:OTTMUSG00000026150 +231510 Gpat3 MGI:MGI:3603816|Ensembl:ENSMUSG00000029314|Vega:OTTMUSG00000026133 +231532 Arhgap24 MGI:MGI:1922647|Ensembl:ENSMUSG00000057315|Vega:OTTMUSG00000023079 +231549 Lrrc8d MGI:MGI:1922368|Ensembl:ENSMUSG00000046079|Vega:OTTMUSG00000026388 +231570 A830010M20Rik MGI:MGI:2445097|Ensembl:ENSMUSG00000044060|Ensembl:ENSMUSG00000111375|Vega:OTTMUSG00000030610 +231571 Rpap2 MGI:MGI:2141142|Ensembl:ENSMUSG00000033773|Vega:OTTMUSG00000023390 +231580 Gak MGI:MGI:2442153|Ensembl:ENSMUSG00000062234|Vega:OTTMUSG00000027010 +231583 Slc26a1 MGI:MGI:2385894|Ensembl:ENSMUSG00000046959|Vega:OTTMUSG00000027011 +231589 Vmn2r13 MGI:MGI:3761379|Ensembl:ENSMUSG00000091635|Vega:OTTMUSG00000039862 +231591 Vmn2r14 MGI:MGI:3649151|Ensembl:ENSMUSG00000091059|Vega:OTTMUSG00000039863 +231600 Chfr MGI:MGI:2444898|Ensembl:ENSMUSG00000014668|Vega:OTTMUSG00000054048 +231602 P2rx2 MGI:MGI:2665170|Ensembl:ENSMUSG00000029503|Vega:OTTMUSG00000054126 +231603 A630023P12Rik MGI:MGI:2445162|Ensembl:ENSMUSG00000048215 +231605 Galnt9 MGI:MGI:2677965|Ensembl:ENSMUSG00000033316|Vega:OTTMUSG00000054216 +231620 LOC231620 - +231630 Ficd MGI:MGI:1098550|Ensembl:ENSMUSG00000053334|Vega:OTTMUSG00000054496 +231633 Tmem119 MGI:MGI:2385228|Ensembl:ENSMUSG00000054675|Vega:OTTMUSG00000028784 +231637 Ssh1 MGI:MGI:2686240|Ensembl:ENSMUSG00000042121|Vega:OTTMUSG00000025799 +231642 Alkbh2 MGI:MGI:2141032|Ensembl:ENSMUSG00000044339|Vega:OTTMUSG00000014449 +231646 Myo1h MGI:MGI:1914674|Ensembl:ENSMUSG00000066952|Vega:OTTMUSG00000014433 +231655 Oasl1 MGI:MGI:2180849|Ensembl:ENSMUSG00000041827|Vega:OTTMUSG00000014607 +231659 Gcn1l1 MGI:MGI:2444248|Ensembl:ENSMUSG00000041638|Vega:OTTMUSG00000014702 +231668 Vsig10 MGI:MGI:2448533|Ensembl:ENSMUSG00000066894|Vega:OTTMUSG00000025764 +231670 Fbxo21 MGI:MGI:1924223|Ensembl:ENSMUSG00000032898|Vega:OTTMUSG00000056149 +231672 Fbxw8 MGI:MGI:1923041|Ensembl:ENSMUSG00000032867|Vega:OTTMUSG00000056152 +231691 Sds MGI:MGI:98270|Ensembl:ENSMUSG00000029597|Vega:OTTMUSG00000025315 +231699 Oas1e MGI:MGI:2180856|Ensembl:ENSMUSG00000066867|Vega:OTTMUSG00000056264 +231712 Trafd1 MGI:MGI:1923551|Ensembl:ENSMUSG00000042726|Vega:OTTMUSG00000026315 +231713 Naa25 MGI:MGI:2442563|Ensembl:ENSMUSG00000042719|Vega:OTTMUSG00000026322 +231717 Fam109a MGI:MGI:2442708|Ensembl:ENSMUSG00000044134|Vega:OTTMUSG00000054365 +231724 Rad9b MGI:MGI:2385231|Ensembl:ENSMUSG00000038569|Vega:OTTMUSG00000026685 +231727 B3gnt4 MGI:MGI:2680208|Ensembl:ENSMUSG00000029431|Vega:OTTMUSG00000025926 +231736 Gm4868 MGI:MGI:3648712 +231760 Rimbp2 MGI:MGI:2443235|Ensembl:ENSMUSG00000029420|Vega:OTTMUSG00000055220 +231769 Sfswap MGI:MGI:101760|Ensembl:ENSMUSG00000029439|Vega:OTTMUSG00000055315 +231798 Lrch4 MGI:MGI:1917193|Ensembl:ENSMUSG00000029720|Ensembl:ENSMUSG00000093445|Vega:OTTMUSG00000040073|Vega:OTTMUSG00000040080 +231801 Agfg2 MGI:MGI:2443267|Ensembl:ENSMUSG00000029722|Vega:OTTMUSG00000021990 +231803 Mepce MGI:MGI:106477|Ensembl:ENSMUSG00000029726|Vega:OTTMUSG00000022853 +231805 Pilra MGI:MGI:2450529|Ensembl:ENSMUSG00000046245|Vega:OTTMUSG00000022871 +231807 BC037034 MGI:MGI:2385896|Ensembl:ENSMUSG00000036948|Vega:OTTMUSG00000022753 +231821 Adap1 MGI:MGI:2442201|Ensembl:ENSMUSG00000056413|Vega:OTTMUSG00000025185 +231830 Micall2 MGI:MGI:2444818|Ensembl:ENSMUSG00000036718|Vega:OTTMUSG00000036853 +231832 Tmem184a MGI:MGI:2385897|Ensembl:ENSMUSG00000036687|Vega:OTTMUSG00000025264 +231834 Snx8 MGI:MGI:2443816|Ensembl:ENSMUSG00000029560|Vega:OTTMUSG00000054814 +231836 Gm4869 MGI:MGI:3646257 +231841 Brat1 MGI:MGI:1891679|Ensembl:ENSMUSG00000000148|Vega:OTTMUSG00000024801 +231842 Amz1 MGI:MGI:2442258|Ensembl:ENSMUSG00000050022|Vega:OTTMUSG00000026842 +231855 Ap5z1 MGI:MGI:1924908|Ensembl:ENSMUSG00000039623|Vega:OTTMUSG00000054867 +231858 Radil MGI:MGI:2443088|Ensembl:ENSMUSG00000029576|Vega:OTTMUSG00000026074 +231861 Tnrc18 MGI:MGI:3648294|Ensembl:ENSMUSG00000039477|Vega:OTTMUSG00000017461 +231863 Fbxl18 MGI:MGI:2444450|Ensembl:ENSMUSG00000066640|Vega:OTTMUSG00000026101 +231866 Zfp12 MGI:MGI:99157|Ensembl:ENSMUSG00000029587|Vega:OTTMUSG00000022885 +231868 E130309D02Rik MGI:MGI:2442621|Ensembl:ENSMUSG00000039244|Vega:OTTMUSG00000026858 +231869 Gm4870 MGI:MGI:3779442 +231871 Daglb MGI:MGI:2442032|Ensembl:ENSMUSG00000039206|Vega:OTTMUSG00000021320 +231872 Aimp2 MGI:MGI:2385237|Ensembl:ENSMUSG00000029610|Vega:OTTMUSG00000025495 +231874 Ccz1 MGI:MGI:2141070|Ensembl:ENSMUSG00000029617|Vega:OTTMUSG00000054939 +231876 Lmtk2 MGI:MGI:3036247|Ensembl:ENSMUSG00000038970|Vega:OTTMUSG00000042434 +231885 Gm4871 MGI:MGI:3648713|Ensembl:ENSMUSG00000061707|Vega:OTTMUSG00000054977 +231887 Pdap1 MGI:MGI:2448536|Ensembl:ENSMUSG00000029623|Vega:OTTMUSG00000022988 +231889 Bud31 MGI:MGI:2141291|Ensembl:ENSMUSG00000038722|Vega:OTTMUSG00000022996 +231903 Urad MGI:MGI:3647519|Ensembl:ENSMUSG00000075543|Vega:OTTMUSG00000044795 +231912 Katnal1 MGI:MGI:2387638|Ensembl:ENSMUSG00000041298|Vega:OTTMUSG00000021231 +231915 Uspl1 MGI:MGI:2442342|Ensembl:ENSMUSG00000041264|Vega:OTTMUSG00000028825 +231931 Gimap6 MGI:MGI:1918876|Ensembl:ENSMUSG00000047867|Vega:OTTMUSG00000026908 +231932 Gimap7 MGI:MGI:1349657|Ensembl:ENSMUSG00000043931|Vega:OTTMUSG00000026927 +231946 Fam221a MGI:MGI:2442161|Ensembl:ENSMUSG00000047115|Vega:OTTMUSG00000026962 +231986 Jazf1 MGI:MGI:2141450|Ensembl:ENSMUSG00000063568|Vega:OTTMUSG00000023834 +231989 Gm4872 MGI:MGI:3779443|Ensembl:ENSMUSG00000107935 +231991 Creb5 MGI:MGI:2443973|Ensembl:ENSMUSG00000053007|Vega:OTTMUSG00000057134 +231997 Fkbp14 MGI:MGI:2387639|Ensembl:ENSMUSG00000038074|Vega:OTTMUSG00000026988 +231999 Plekha8 MGI:MGI:2681164|Ensembl:ENSMUSG00000005225|Vega:OTTMUSG00000026986 +232016 Ccdc129 MGI:MGI:2685304|Ensembl:ENSMUSG00000037973|Vega:OTTMUSG00000036761 +232023 Vopp1 MGI:MGI:2141658|Ensembl:ENSMUSG00000037788|Vega:OTTMUSG00000033997 +232035 Ccser1 MGI:MGI:3045354|Ensembl:ENSMUSG00000039578|Vega:OTTMUSG00000034146 +232047 Gm4873 MGI:MGI:3648522 +232065 Igkv8-19 MGI:MGI:1330844|IMGT/GENE-DB:IGKV8-19 +232077 Foxi3 MGI:MGI:3511278|Ensembl:ENSMUSG00000055874|Vega:OTTMUSG00000034294 +232078 Thnsl2 MGI:MGI:3041254|Ensembl:ENSMUSG00000054474|Vega:OTTMUSG00000034784 +232086 Tmem150a MGI:MGI:2385244|Ensembl:ENSMUSG00000055912|Vega:OTTMUSG00000023352 +232087 Mat2a MGI:MGI:2443731|Ensembl:ENSMUSG00000053907|Vega:OTTMUSG00000057919 +232089 Elmod3 MGI:MGI:2445168|Ensembl:ENSMUSG00000056698|Vega:OTTMUSG00000023557 +232143 Gm4874 MGI:MGI:3647948 +232146 Eva1a MGI:MGI:2385247|Ensembl:ENSMUSG00000035104|Vega:OTTMUSG00000027004 +232156 Slc4a5 MGI:MGI:2443220|Ensembl:ENSMUSG00000068323|Vega:OTTMUSG00000022619 +232157 Mob1a MGI:MGI:2442631|Ensembl:ENSMUSG00000043131|Vega:OTTMUSG00000022699 +232164 Paip2b MGI:MGI:2386865|Ensembl:ENSMUSG00000045896|Vega:OTTMUSG00000023448 +232174 Cyp26b1 MGI:MGI:2176159|Ensembl:ENSMUSG00000063415|Vega:OTTMUSG00000057844 +232187 Smyd5 MGI:MGI:108048|Ensembl:ENSMUSG00000033706|Vega:OTTMUSG00000017438 +232196 C87436 MGI:MGI:2141787|Ensembl:ENSMUSG00000046679|Vega:OTTMUSG00000024070 +232201 Arhgap25 MGI:MGI:2443687|Ensembl:ENSMUSG00000030047|Vega:OTTMUSG00000023045 +232210 Hmces MGI:MGI:1914053|Ensembl:ENSMUSG00000030060|Vega:OTTMUSG00000023514 +232217 4933427D06Rik MGI:MGI:3026922|Ensembl:ENSMUSG00000055403 +232223 Txnrd3 MGI:MGI:2386711|Ensembl:ENSMUSG00000000811|Vega:OTTMUSG00000021186 +232227 Iqsec1 MGI:MGI:1196356|Ensembl:ENSMUSG00000034312|Vega:OTTMUSG00000029729 +232232 Hdac11 MGI:MGI:2385252|Ensembl:ENSMUSG00000034245|Vega:OTTMUSG00000017285 +232236 Ccdc174 MGI:MGI:2444652|Ensembl:ENSMUSG00000034083|Vega:OTTMUSG00000023753 +232237 Fgd5 MGI:MGI:2443369|Ensembl:ENSMUSG00000034037|Vega:OTTMUSG00000023856 +232286 Tmf1 MGI:MGI:2684999|Ensembl:ENSMUSG00000030059|Vega:OTTMUSG00000029717 +232288 Frmd4b MGI:MGI:2141794|Ensembl:ENSMUSG00000030064|Vega:OTTMUSG00000023096 +232313 Gxylt2 MGI:MGI:2682940|Ensembl:ENSMUSG00000030074|Vega:OTTMUSG00000023979 +232314 Ppp4r2 MGI:MGI:3027896|Ensembl:ENSMUSG00000052144|Vega:OTTMUSG00000057214 +232333 Slc6a1 MGI:MGI:95627|Ensembl:ENSMUSG00000030310|Vega:OTTMUSG00000056591 +232334 Vgll4 MGI:MGI:2652840|Ensembl:ENSMUSG00000030315|Vega:OTTMUSG00000023607 +232337 Zfp637 MGI:MGI:2448537|Ensembl:ENSMUSG00000059689|Vega:OTTMUSG00000022146 +232338 Gm4875 MGI:MGI:3648108 +232339 Ankrd26 MGI:MGI:1917887|Ensembl:ENSMUSG00000007827|Vega:OTTMUSG00000048361 +232341 Wnk1 MGI:MGI:2442092|Ensembl:ENSMUSG00000045962|Vega:OTTMUSG00000031633 +232345 A2m MGI:MGI:2449119|Ensembl:ENSMUSG00000030111|Vega:OTTMUSG00000056872 +232358 Vmn2r19 MGI:MGI:3647444|Ensembl:ENSMUSG00000091260|Vega:OTTMUSG00000040016 +232367 Vmn2r27 MGI:MGI:3761517|Ensembl:ENSMUSG00000072778|Vega:OTTMUSG00000040041 +232370 Clstn3 MGI:MGI:2178323|Ensembl:ENSMUSG00000008153|Vega:OTTMUSG00000022801 +232371 C1rl MGI:MGI:2660692|Ensembl:ENSMUSG00000038527|Vega:OTTMUSG00000022316 +232386 Gm38404 MGI:MGI:5621289|Ensembl:ENSMUSG00000107153 +232400 A2ml1 MGI:MGI:3039594|Ensembl:ENSMUSG00000047228|Vega:OTTMUSG00000056389 +232406 BC035044 MGI:MGI:2448540|Ensembl:ENSMUSG00000090164|Vega:OTTMUSG00000034581 +232408 Klrb1f MGI:MGI:2442965|Ensembl:ENSMUSG00000030154|Vega:OTTMUSG00000056394 +232409 Clec2e MGI:MGI:3028921|Ensembl:ENSMUSG00000030155|Vega:OTTMUSG00000056463 +232413 Clec12a MGI:MGI:3040968|Ensembl:ENSMUSG00000053063|Vega:OTTMUSG00000026999 +232414 Clec9a MGI:MGI:2444608|Ensembl:ENSMUSG00000046080|Vega:OTTMUSG00000027008 +232415 Gm156 MGI:MGI:2685002|Ensembl:ENSMUSG00000071158|Vega:OTTMUSG00000027067 +232426 5530400C23Rik MGI:MGI:1918650|Ensembl:ENSMUSG00000055594|Vega:OTTMUSG00000034592 +232430 Crebl2 MGI:MGI:1889385|Ensembl:ENSMUSG00000032652|Vega:OTTMUSG00000023987 +232431 Gprc5a MGI:MGI:1891250|Ensembl:ENSMUSG00000046733|Vega:OTTMUSG00000023088 +232440 H2afj MGI:MGI:3606192|Ensembl:ENSMUSG00000060032|Vega:OTTMUSG00000022214 +232441 Rerg MGI:MGI:2665139|Ensembl:ENSMUSG00000030222|Vega:OTTMUSG00000027079 +232449 Dera MGI:MGI:1913762|Ensembl:ENSMUSG00000030225|Vega:OTTMUSG00000057550 +232491 Pyroxd1 MGI:MGI:2676395|Ensembl:ENSMUSG00000041671|Vega:OTTMUSG00000022477 +232493 Gys2 MGI:MGI:2385254|Ensembl:ENSMUSG00000030244|Vega:OTTMUSG00000023569 +232533 Stk38l MGI:MGI:1922250|Ensembl:ENSMUSG00000001630|Vega:OTTMUSG00000025646 +232536 Mrps35 MGI:MGI:2385255|Ensembl:ENSMUSG00000040112|Vega:OTTMUSG00000023793 +232539 Klhl42 MGI:MGI:2444786|Ensembl:ENSMUSG00000040102|Vega:OTTMUSG00000026057 +232560 Caprin2 MGI:MGI:2448541|Ensembl:ENSMUSG00000030309|Vega:OTTMUSG00000023388 +232566 Amn1 MGI:MGI:2442933|Ensembl:ENSMUSG00000068250|Vega:OTTMUSG00000024377 +232585 Vwde MGI:MGI:2685313|Ensembl:ENSMUSG00000079679|Vega:OTTMUSG00000057084 +232599 Gm4876 MGI:MGI:3647654 +232664 Ccdc136 MGI:MGI:1918128|Ensembl:ENSMUSG00000029769|Vega:OTTMUSG00000023565 +232670 Tspan33 MGI:MGI:1919012|Ensembl:ENSMUSG00000001763|Vega:OTTMUSG00000013447 +232679 Zc3hc1 MGI:MGI:1916023|Ensembl:ENSMUSG00000039130|Vega:OTTMUSG00000014349 +232680 Cpa2 MGI:MGI:3617840|Ensembl:ENSMUSG00000071553|Vega:OTTMUSG00000014390 +232685 Lncpint MGI:MGI:2673128|Ensembl:ENSMUSG00000044471 +232714 Mgam MGI:MGI:1203495|Ensembl:ENSMUSG00000068587|Vega:OTTMUSG00000056380 +232717 Prss58 MGI:MGI:3608323|Ensembl:ENSMUSG00000051936|Vega:OTTMUSG00000051415 +232745 Gm4877 MGI:MGI:3779444 +232748 Tcaf2 MGI:MGI:2385258|Ensembl:ENSMUSG00000029851|Vega:OTTMUSG00000027059 +232784 Zfp212 MGI:MGI:2682609|Ensembl:ENSMUSG00000052763|Vega:OTTMUSG00000029727 +232785 Zfp783 MGI:MGI:3040704|Ensembl:ENSMUSG00000072653 +232790 Oscar MGI:MGI:2179720|Ensembl:ENSMUSG00000054594|Vega:OTTMUSG00000021060 +232791 Cnot3 MGI:MGI:2385261|Ensembl:ENSMUSG00000035632|Vega:OTTMUSG00000027888 +232798 Leng8 MGI:MGI:2142195|Ensembl:ENSMUSG00000035545|Vega:OTTMUSG00000027891 +232801 Lilra5 MGI:MGI:3647196|Ensembl:ENSMUSG00000070873|Vega:OTTMUSG00000027903 +232807 Ppp1r12c MGI:MGI:1924258|Ensembl:ENSMUSG00000019254|Vega:OTTMUSG00000024437 +232811 Kmt5c MGI:MGI:2385262|Ensembl:ENSMUSG00000059851|Vega:OTTMUSG00000017303 +232813 Shisa7 MGI:MGI:3605641|Ensembl:ENSMUSG00000053550|Vega:OTTMUSG00000027095 +232816 Zfp628 MGI:MGI:2665174|Ensembl:ENSMUSG00000074406|Vega:OTTMUSG00000058582 +232821 Ccdc106 MGI:MGI:2385900|Ensembl:ENSMUSG00000035228|Vega:OTTMUSG00000023013 +232827 Nlrp2 MGI:MGI:3041206|Ensembl:ENSMUSG00000035177|Vega:OTTMUSG00000037748 +232836 Galp MGI:MGI:2663979|Ensembl:ENSMUSG00000034660|Vega:OTTMUSG00000031409 +232853 Zfp954 MGI:MGI:1917764|Ensembl:ENSMUSG00000062116|Vega:OTTMUSG00000033615 +232854 Zfp418 MGI:MGI:2444763|Ensembl:ENSMUSG00000034538|Vega:OTTMUSG00000036571 +232855 Zfp772 MGI:MGI:2385265|Ensembl:ENSMUSG00000066838|Vega:OTTMUSG00000060158 +232867 Gm17737 MGI:MGI:5009814 +232875 Zscan18 MGI:MGI:3643810|Ensembl:ENSMUSG00000070822|Vega:OTTMUSG00000060748 +232878 Zscan22 MGI:MGI:2443312|Ensembl:ENSMUSG00000054715|Vega:OTTMUSG00000027134 +232879 Zbtb45 MGI:MGI:2685003|Ensembl:ENSMUSG00000049600|Vega:OTTMUSG00000060867 +232887 Gm4879 MGI:MGI:3648111 +232889 Pla2g4c MGI:MGI:1196403|Ensembl:ENSMUSG00000033847|Vega:OTTMUSG00000036437 +232906 Arhgap35 MGI:MGI:1929494|Ensembl:ENSMUSG00000058230|Vega:OTTMUSG00000048052 +232910 Ap2s1 MGI:MGI:2141861|Ensembl:ENSMUSG00000008036|Vega:OTTMUSG00000022892 +232919 Psg-ps1 MGI:MGI:1347253|Ensembl:ENSMUSG00000108558 +232925 Igfl3 MGI:MGI:2685426|Ensembl:ENSMUSG00000066756|Vega:OTTMUSG00000032615 +232930 Gm4880 MGI:MGI:3648786 +232933 Ccdc61 MGI:MGI:2685005|Ensembl:ENSMUSG00000074358|Vega:OTTMUSG00000031943 +232934 Mypop MGI:MGI:2446472|Ensembl:ENSMUSG00000048481|Vega:OTTMUSG00000032924 +232941 Ppm1n MGI:MGI:2142330|Ensembl:ENSMUSG00000030402|Vega:OTTMUSG00000058603 +232943 Klc3 MGI:MGI:1277971|Ensembl:ENSMUSG00000040714|Vega:OTTMUSG00000023189 +232944 Mark4 MGI:MGI:1920955|Ensembl:ENSMUSG00000030397|Vega:OTTMUSG00000059238 +232946 Bloc1s3 MGI:MGI:2678952|Ensembl:ENSMUSG00000057667|Vega:OTTMUSG00000059241 +232947 Ppp1r37 MGI:MGI:2687042|Ensembl:ENSMUSG00000051403|Vega:OTTMUSG00000059252 +232959 Vmn1r178 MGI:MGI:3033482|Ensembl:ENSMUSG00000062598|Vega:OTTMUSG00000038012 +232962 Vmn1r180 MGI:MGI:3033485|Ensembl:ENSMUSG00000092473|Vega:OTTMUSG00000038014 +232966 Zfp114 MGI:MGI:3037815|Ensembl:ENSMUSG00000068962|Vega:OTTMUSG00000058067 +232969 Zfp428 MGI:MGI:1916463|Ensembl:ENSMUSG00000064264|Vega:OTTMUSG00000042105 +232970 Phldb3 MGI:MGI:3642959|Ensembl:ENSMUSG00000074277|Vega:OTTMUSG00000058224 +232972 BC049730 MGI:MGI:2681843|Ensembl:ENSMUSG00000045587|Vega:OTTMUSG00000058232 +232973 Lypd4 MGI:MGI:2687054|Ensembl:ENSMUSG00000062732|Vega:OTTMUSG00000024042 +232974 Gm4881 MGI:MGI:3642958|Ensembl:ENSMUSG00000108367|Vega:OTTMUSG00000058238 +232975 Atp1a3 MGI:MGI:88107|Ensembl:ENSMUSG00000040907|Vega:OTTMUSG00000016491 +232976 Zfp574 MGI:MGI:2442951|Ensembl:ENSMUSG00000045252|Vega:OTTMUSG00000058242 +232983 Cxcl17 MGI:MGI:2387642|Ensembl:ENSMUSG00000060188|Vega:OTTMUSG00000055594 +232984 B3gnt8 MGI:MGI:2385269|Ensembl:ENSMUSG00000059479|Vega:OTTMUSG00000058393 +232987 B9d2 MGI:MGI:2387643|Ensembl:ENSMUSG00000063439|Vega:OTTMUSG00000058397 +232989 Hnrnpul1 MGI:MGI:2443517|Ensembl:ENSMUSG00000040725|Vega:OTTMUSG00000058398 +232993 Cyp2b28-ps MGI:MGI:3716993 +233001 Nlrp9a MGI:MGI:2675292|Ensembl:ENSMUSG00000054102|Vega:OTTMUSG00000031796 +233005 Cyp2a22 MGI:MGI:3648316|Ensembl:ENSMUSG00000091867|Vega:OTTMUSG00000058548 +233011 Itpkc MGI:MGI:2442554|Ensembl:ENSMUSG00000003752|Vega:OTTMUSG00000023456 +233016 Blvrb MGI:MGI:2385271|Ensembl:ENSMUSG00000040466|Vega:OTTMUSG00000023260 +233020 Hipk4 MGI:MGI:2685008|Ensembl:ENSMUSG00000040424|Vega:OTTMUSG00000022752 +233033 Samd4b MGI:MGI:2448542|Ensembl:ENSMUSG00000109336|Vega:OTTMUSG00000059057 +233038 Nccrp1 MGI:MGI:2685009|Ensembl:ENSMUSG00000047586|Vega:OTTMUSG00000059063 +233040 Fbxo27 MGI:MGI:2685007|Ensembl:ENSMUSG00000037463|Vega:OTTMUSG00000023145 +233045 Gm26604 MGI:MGI:5477098 +233046 Rasgrp4 MGI:MGI:2386851|Ensembl:ENSMUSG00000030589|Vega:OTTMUSG00000033130 +233056 Zfp790 MGI:MGI:1923431|Ensembl:ENSMUSG00000011427|Vega:OTTMUSG00000059222 +233057 Zfp940 MGI:MGI:2446235|Ensembl:ENSMUSG00000050855|Vega:OTTMUSG00000022386 +233058 Zfp420 MGI:MGI:2444666|Ensembl:ENSMUSG00000058402|Vega:OTTMUSG00000022401 +233060 Zfp382 MGI:MGI:3588204|Ensembl:ENSMUSG00000074220|Vega:OTTMUSG00000029962 +233064 Wdr62 MGI:MGI:1923696|Ensembl:ENSMUSG00000037020|Vega:OTTMUSG00000024362 +233065 Alkbh6 MGI:MGI:2142037|Ensembl:ENSMUSG00000042831|Vega:OTTMUSG00000026579 +233066 Syne4 MGI:MGI:2141950|Ensembl:ENSMUSG00000019737|Vega:OTTMUSG00000040160 +233067 Lrfn3 MGI:MGI:2442512|Ensembl:ENSMUSG00000036957|Vega:OTTMUSG00000059314 +233071 Arhgap33 MGI:MGI:2673998|Ensembl:ENSMUSG00000036882|Vega:OTTMUSG00000059362 +233073 U2af1l4 MGI:MGI:2678374|Ensembl:ENSMUSG00000078765|Ensembl:ENSMUSG00000109378|Vega:OTTMUSG00000036722|Vega:OTTMUSG00000059365 +233075 Gm4883 MGI:MGI:3643348 +233079 Ffar2 MGI:MGI:2441731|Ensembl:ENSMUSG00000051314|Vega:OTTMUSG00000049767 +233080 Ffar3 MGI:MGI:2685324|Ensembl:ENSMUSG00000019429|Vega:OTTMUSG00000049768 +233081 Ffar1 MGI:MGI:2684079|Ensembl:ENSMUSG00000044453|Vega:OTTMUSG00000049770 +233090 Scgb2b24 MGI:MGI:2655741|Ensembl:ENSMUSG00000046438|Vega:OTTMUSG00000008401 +233099 Scgb2b27 MGI:MGI:87863|Ensembl:ENSMUSG00000066584|Vega:OTTMUSG00000008400 +233103 4931406P16Rik MGI:MGI:1924311|Ensembl:ENSMUSG00000066571|Vega:OTTMUSG00000008390 +233107 Kctd15 MGI:MGI:2385276|Ensembl:ENSMUSG00000030499|Vega:OTTMUSG00000008374 +233115 Dpy19l3 MGI:MGI:2443952|Ensembl:ENSMUSG00000043671|Vega:OTTMUSG00000030802 +233147 Zfp939 MGI:MGI:3036240|Ensembl:ENSMUSG00000030424 +233164 Gm4884 MGI:MGI:3649090|Ensembl:ENSMUSG00000048312|Vega:OTTMUSG00000048545 +233168 AI987944 MGI:MGI:2142079|Ensembl:ENSMUSG00000056383|Vega:OTTMUSG00000035890 +233186 Siglecf MGI:MGI:2681107|Ensembl:ENSMUSG00000039013|Vega:OTTMUSG00000031683 +233187 Lim2 MGI:MGI:104698|Ensembl:ENSMUSG00000004613|Vega:OTTMUSG00000039806 +233189 Ctu1 MGI:MGI:2385277|Ensembl:ENSMUSG00000038888|Vega:OTTMUSG00000027175 +233199 Mybpc2 MGI:MGI:1336170|Ensembl:ENSMUSG00000038670|Vega:OTTMUSG00000058331 +233204 Tbc1d17 MGI:MGI:2449973|Ensembl:ENSMUSG00000038520|Vega:OTTMUSG00000023129 +233208 Scaf1 MGI:MGI:2141980|Ensembl:ENSMUSG00000038406|Vega:OTTMUSG00000028917 +233210 Prr12 MGI:MGI:2679002|Ensembl:ENSMUSG00000046574|Vega:OTTMUSG00000058292 +233221 Mrgpra1 MGI:MGI:3033095|Ensembl:ENSMUSG00000050650|Vega:OTTMUSG00000038088 +233222 Mrgpra3 MGI:MGI:2684085|Ensembl:ENSMUSG00000078698|Vega:OTTMUSG00000028718 +233230 Mrgprb4 MGI:MGI:3033119|Ensembl:ENSMUSG00000070550|Vega:OTTMUSG00000046610 +233231 Mrgprb1 MGI:MGI:3033115|Ensembl:ENSMUSG00000070547|Vega:OTTMUSG00000046625 +233246 Ano5 MGI:MGI:3576659|Ensembl:ENSMUSG00000055489|Vega:OTTMUSG00000059013 +233271 Luzp2 MGI:MGI:1889615|Ensembl:ENSMUSG00000063297|Vega:OTTMUSG00000058810 +233274 Siglech MGI:MGI:2443256|Ensembl:ENSMUSG00000051504|Vega:OTTMUSG00000027292 +233276 Tubgcp5 MGI:MGI:2178836|Ensembl:ENSMUSG00000033790|Vega:OTTMUSG00000058826 +233280 Nipa1 MGI:MGI:2442058|Ensembl:ENSMUSG00000047037|Vega:OTTMUSG00000026329 +233315 Mtmr10 MGI:MGI:2142292|Ensembl:ENSMUSG00000030522|Vega:OTTMUSG00000037228 +233328 Lrrk1 MGI:MGI:2142227|Ensembl:ENSMUSG00000015133|Vega:OTTMUSG00000024885 +233332 Adamts17 MGI:MGI:3588195|Ensembl:ENSMUSG00000058145|Vega:OTTMUSG00000024145 +233335 Synm MGI:MGI:2661187|Ensembl:ENSMUSG00000030554|Vega:OTTMUSG00000059487 +233391 Kansl2-ps MGI:MGI:3648525 +233405 Vps33b MGI:MGI:2446237|Ensembl:ENSMUSG00000030534|Vega:OTTMUSG00000017577 +233406 Prc1 MGI:MGI:1858961|Ensembl:ENSMUSG00000038943|Vega:OTTMUSG00000037307 +233410 Zfp592 MGI:MGI:2443541|Ensembl:ENSMUSG00000005621|Vega:OTTMUSG00000023910 +233424 Tmc3 MGI:MGI:2669033|Ensembl:ENSMUSG00000038540|Vega:OTTMUSG00000036826 +233437 Vmn2r66 MGI:MGI:3588220|Ensembl:ENSMUSG00000094950|Vega:OTTMUSG00000033221 +233445 Vmn2r71 MGI:MGI:3646472|Ensembl:ENSMUSG00000091205|Vega:OTTMUSG00000037817 +233489 Picalm MGI:MGI:2385902|Ensembl:ENSMUSG00000039361|Vega:OTTMUSG00000059751 +233490 Crebzf MGI:MGI:2675296|Ensembl:ENSMUSG00000051451|Vega:OTTMUSG00000022882 +233529 Kctd14 MGI:MGI:1289222|Ensembl:ENSMUSG00000051727|Vega:OTTMUSG00000029543 +233532 Rsf1 MGI:MGI:2682305|Ensembl:ENSMUSG00000035623|Vega:OTTMUSG00000017281 +233537 Gdpd4 MGI:MGI:3606573|Ensembl:ENSMUSG00000035582|Vega:OTTMUSG00000029700 +233544 A630091E08Rik MGI:MGI:2442837 +233545 Emsy MGI:MGI:1924203|Ensembl:ENSMUSG00000035401|Vega:OTTMUSG00000058884 +233549 Mogat2 MGI:MGI:2663253|Ensembl:ENSMUSG00000052396|Vega:OTTMUSG00000027299 +233552 Gdpd5 MGI:MGI:2686926|Ensembl:ENSMUSG00000035314|Vega:OTTMUSG00000058978 +233561 Gm38405 MGI:MGI:5621290 +233571 P2ry6 MGI:MGI:2673874|Ensembl:ENSMUSG00000048779|Vega:OTTMUSG00000060006 +233575 Pgap2 MGI:MGI:2385286|Ensembl:ENSMUSG00000030990|Vega:OTTMUSG00000030548 +233578 Olfr553 MGI:MGI:3030387|Ensembl:ENSMUSG00000073972|Vega:OTTMUSG00000060020 +233614 Gm4886 MGI:MGI:3645929 +233637 Gm4887 MGI:MGI:3645730 +233649 Cnga4 MGI:MGI:2664099|Ensembl:ENSMUSG00000030897|Vega:OTTMUSG00000060484 +233651 Dchs1 MGI:MGI:2685011|Ensembl:ENSMUSG00000036862|Vega:OTTMUSG00000014997 +233670 Olfr6 MGI:MGI:104713|Ensembl:ENSMUSG00000036647|Vega:OTTMUSG00000059728 +233724 Tmem41b MGI:MGI:1289225|Ensembl:ENSMUSG00000047554|Vega:OTTMUSG00000028635 +233726 Ipo7 MGI:MGI:2152414|Ensembl:ENSMUSG00000066232|Vega:OTTMUSG00000060142 +233733 Galnt18 MGI:MGI:2446239|Ensembl:ENSMUSG00000038296|Vega:OTTMUSG00000024317 +233744 Spon1 MGI:MGI:2385287|Ensembl:ENSMUSG00000038156|Vega:OTTMUSG00000024553 +233752 Insc MGI:MGI:1917942|Ensembl:ENSMUSG00000048782|Vega:OTTMUSG00000030984 +233765 Plekha7 MGI:MGI:2445094|Ensembl:ENSMUSG00000045659|Vega:OTTMUSG00000043408 +233781 Xylt1 MGI:MGI:2451073|Ensembl:ENSMUSG00000030657|Vega:OTTMUSG00000032722 +233789 Smg1 MGI:MGI:1919742|Ensembl:ENSMUSG00000030655|Vega:OTTMUSG00000042422 +233799 Acsm2 MGI:MGI:2385289|Ensembl:ENSMUSG00000030945|Vega:OTTMUSG00000027306 +233801 Acsm4 MGI:MGI:2681844|Ensembl:ENSMUSG00000047026|Vega:OTTMUSG00000023914 +233802 Thumpd1 MGI:MGI:2444479|Ensembl:ENSMUSG00000030942|Vega:OTTMUSG00000059138 +233805 Dcun1d3 MGI:MGI:2679003|Ensembl:ENSMUSG00000048787|Vega:OTTMUSG00000025619 +233806 Tmem159 MGI:MGI:1925752|Ensembl:ENSMUSG00000030917|Vega:OTTMUSG00000027377 +233810 Abca16 MGI:MGI:2388711|Ensembl:ENSMUSG00000051900|Vega:OTTMUSG00000029808 +233812 BC030336 MGI:MGI:2446240|Ensembl:ENSMUSG00000046096|Vega:OTTMUSG00000059289 +233813 Vwa3a MGI:MGI:3041229|Ensembl:ENSMUSG00000030889|Vega:OTTMUSG00000036605 +233824 Cog7 MGI:MGI:2685013|Ensembl:ENSMUSG00000034951|Vega:OTTMUSG00000026116 +233826 Palb2 MGI:MGI:3040695|Ensembl:ENSMUSG00000044702|Vega:OTTMUSG00000022651 +233833 Tnrc6a MGI:MGI:2385292|Ensembl:ENSMUSG00000052707|Vega:OTTMUSG00000058124 +233836 Slc5a11 MGI:MGI:1919316|Ensembl:ENSMUSG00000030769|Vega:OTTMUSG00000030939 +233863 Gtf3c1 MGI:MGI:107887|Ensembl:ENSMUSG00000032777|Vega:OTTMUSG00000058204 +233865 D430042O09Rik MGI:MGI:2442760|Ensembl:ENSMUSG00000032743|Vega:OTTMUSG00000030952 +233870 Tufm MGI:MGI:1923686|Ensembl:ENSMUSG00000073838|Vega:OTTMUSG00000058216 +233871 Atxn2l MGI:MGI:2446242|Ensembl:ENSMUSG00000032637|Vega:OTTMUSG00000042400 +233875 Ino80e MGI:MGI:2141881|Ensembl:ENSMUSG00000030689|Vega:OTTMUSG00000023357 +233876 Hirip3 MGI:MGI:2142364|Ensembl:ENSMUSG00000042606|Vega:OTTMUSG00000023359 +233877 Kctd13 MGI:MGI:1923739|Ensembl:ENSMUSG00000030685|Vega:OTTMUSG00000023162 +233878 Sez6l2 MGI:MGI:2385295|Ensembl:ENSMUSG00000030683|Vega:OTTMUSG00000023164 +233879 Asphd1 MGI:MGI:2685014|Ensembl:ENSMUSG00000046378|Vega:OTTMUSG00000023163 +233887 Zfp553 MGI:MGI:2384725|Ensembl:ENSMUSG00000045598|Vega:OTTMUSG00000022479 +233890 Zfp768 MGI:MGI:2384582|Ensembl:ENSMUSG00000047371|Vega:OTTMUSG00000058503 +233893 Zfp764 MGI:MGI:2443580|Ensembl:ENSMUSG00000045757|Vega:OTTMUSG00000022482 +233895 Prr14 MGI:MGI:2384565|Ensembl:ENSMUSG00000030822|Vega:OTTMUSG00000025400 +233899 Ccdc189 MGI:MGI:2685012|Ensembl:ENSMUSG00000057176|Vega:OTTMUSG00000058624 +233900 Rnf40 MGI:MGI:2142048|Ensembl:ENSMUSG00000030816|Vega:OTTMUSG00000058625 +233902 Fbxl19 MGI:MGI:3039600|Ensembl:ENSMUSG00000030811|Vega:OTTMUSG00000046248 +233904 Setd1a MGI:MGI:2446244|Ensembl:ENSMUSG00000042308|Vega:OTTMUSG00000017309 +233905 Zfp646 MGI:MGI:3665412|Ensembl:ENSMUSG00000049739|Vega:OTTMUSG00000022500 +233908 Fus MGI:MGI:1353633|Ensembl:ENSMUSG00000030795|Vega:OTTMUSG00000016476 +233912 Armc5 MGI:MGI:2384586|Ensembl:ENSMUSG00000042178|Vega:OTTMUSG00000058674 +233913 BC017158 MGI:MGI:2384572|Ensembl:ENSMUSG00000030780|Vega:OTTMUSG00000027374 +233918 4933402N03Rik MGI:MGI:1914681|Ensembl:ENSMUSG00000013668|Vega:OTTMUSG00000036750 +233919 Gpr26 MGI:MGI:2441758|Ensembl:ENSMUSG00000040125|Vega:OTTMUSG00000023040 +233977 Ppfia1 MGI:MGI:1924750|Ensembl:ENSMUSG00000037519|Vega:OTTMUSG00000043428 +233979 Tpcn2 MGI:MGI:2385297|Ensembl:ENSMUSG00000048677|Vega:OTTMUSG00000059892 +233987 Zfp958 MGI:MGI:2385298|Ensembl:ENSMUSG00000058748|Vega:OTTMUSG00000055596 +234023 Arglu1 MGI:MGI:2442985|Ensembl:ENSMUSG00000040459|Vega:OTTMUSG00000059828 +234069 Pcid2 MGI:MGI:2443003|Ensembl:ENSMUSG00000038542|Vega:OTTMUSG00000036322 +234072 Adprhl1 MGI:MGI:2442168|Ensembl:ENSMUSG00000031448|Vega:OTTMUSG00000036319 +234076 Tmco3 MGI:MGI:2444946|Ensembl:ENSMUSG00000038497|Vega:OTTMUSG00000060902 +234086 Erich1 MGI:MGI:3588201|Ensembl:ENSMUSG00000051978|Vega:OTTMUSG00000060795 +234094 Arhgef10 MGI:MGI:2444453|Ensembl:ENSMUSG00000071176|Vega:OTTMUSG00000034037 +234129 Tpte MGI:MGI:2446460|Ensembl:ENSMUSG00000031481|Vega:OTTMUSG00000060882 +234130 Dkk4 MGI:MGI:2385299|Ensembl:ENSMUSG00000031535|Vega:OTTMUSG00000060892 +234135 Nsd3 MGI:MGI:2142581|Ensembl:ENSMUSG00000054823|Vega:OTTMUSG00000032895 +234138 Tti2 MGI:MGI:2384576|Ensembl:ENSMUSG00000031577|Vega:OTTMUSG00000060915 +234155 Mboat4 MGI:MGI:2685017|Ensembl:ENSMUSG00000071113|Vega:OTTMUSG00000060997 +234159 Gm4889 MGI:MGI:3647233 +234199 Fgl1 MGI:MGI:102795|Ensembl:ENSMUSG00000031594|Vega:OTTMUSG00000034038 +234203 Zfp353-ps MGI:MGI:2387419 +234214 Sorbs2 MGI:MGI:1924574|Ensembl:ENSMUSG00000031626|Vega:OTTMUSG00000034076 +234219 Helt MGI:MGI:3040955|Ensembl:ENSMUSG00000047171|Vega:OTTMUSG00000061139 +234258 Neil3 MGI:MGI:2384588|Ensembl:ENSMUSG00000039396|Vega:OTTMUSG00000023310 +234267 Gpm6a MGI:MGI:107671|Ensembl:ENSMUSG00000031517|Vega:OTTMUSG00000060637 +234290 BC030500 MGI:MGI:2447770|Ensembl:ENSMUSG00000049946|Vega:OTTMUSG00000027192 +234309 Cbr4 MGI:MGI:2384567|Ensembl:ENSMUSG00000031641|Vega:OTTMUSG00000031403 +234311 Ddx60 MGI:MGI:2384570|Ensembl:ENSMUSG00000037921|Vega:OTTMUSG00000031511 +234329 Trim60 MGI:MGI:2387430|Ensembl:ENSMUSG00000053490|Vega:OTTMUSG00000061288 +234344 Naf1 MGI:MGI:2682306|Ensembl:ENSMUSG00000014907|Vega:OTTMUSG00000031172 +234353 Psd3 MGI:MGI:1918215|Ensembl:ENSMUSG00000030465|Vega:OTTMUSG00000028732 +234356 Csgalnact1 MGI:MGI:2442354|Ensembl:ENSMUSG00000036356|Vega:OTTMUSG00000024914 +234358 Zfp930 MGI:MGI:2675306|Ensembl:ENSMUSG00000059897|Vega:OTTMUSG00000062175 +234362 Zfp868 MGI:MGI:2142546|Ensembl:ENSMUSG00000060427|Vega:OTTMUSG00000031076 +234365 Yjefn3 MGI:MGI:2681845 +234366 Gatad2a MGI:MGI:2384585|Ensembl:ENSMUSG00000036180|Vega:OTTMUSG00000062222 +234371 Tmem161a MGI:MGI:2384577|Ensembl:ENSMUSG00000002342|Vega:OTTMUSG00000022197 +234373 Sugp2 MGI:MGI:2678085|Ensembl:ENSMUSG00000036054|Vega:OTTMUSG00000030135 +234374 Ddx49 MGI:MGI:2136689|Ensembl:ENSMUSG00000057788|Vega:OTTMUSG00000027333 +234378 Klhl26 MGI:MGI:2443079|Ensembl:ENSMUSG00000055707|Vega:OTTMUSG00000061453 +234384 Mpv17l2 MGI:MGI:2681846|Ensembl:ENSMUSG00000035559|Vega:OTTMUSG00000061544 +234388 Ccdc124 MGI:MGI:1916403|Ensembl:ENSMUSG00000007721|Vega:OTTMUSG00000061583 +234395 Ushbp1 MGI:MGI:1922920|Ensembl:ENSMUSG00000034911|Vega:OTTMUSG00000062153 +234396 Ankle1 MGI:MGI:1918775|Ensembl:ENSMUSG00000046295|Vega:OTTMUSG00000029800 +234404 Nxnl1 MGI:MGI:1924446|Ensembl:ENSMUSG00000034829|Vega:OTTMUSG00000062163 +234407 Colgalt1 MGI:MGI:1924348|Ensembl:ENSMUSG00000034807|Vega:OTTMUSG00000062165 +234413 Zfp961 MGI:MGI:3583954|Ensembl:ENSMUSG00000052446|Vega:OTTMUSG00000025161 +234421 Cib3 MGI:MGI:2685953|Ensembl:ENSMUSG00000074240|Vega:OTTMUSG00000062096 +234463 Tmem184c MGI:MGI:2384562|Ensembl:ENSMUSG00000031617|Vega:OTTMUSG00000024397 +234479 Gm4890 MGI:MGI:3779445 +234501 Gm4891 MGI:MGI:3645744 +234515 Inpp4b MGI:MGI:2158925|Ensembl:ENSMUSG00000037940|Vega:OTTMUSG00000035809 +234542 Rtbdn MGI:MGI:2443686|Ensembl:ENSMUSG00000048617|Vega:OTTMUSG00000029901 +234549 Heatr3 MGI:MGI:2444491|Ensembl:ENSMUSG00000031657|Vega:OTTMUSG00000031063 +234564 Ces1f MGI:MGI:2142687|Ensembl:ENSMUSG00000031725|Vega:OTTMUSG00000024519 +234577 Cpne2 MGI:MGI:2387578|Ensembl:ENSMUSG00000034361|Vega:OTTMUSG00000023458 +234582 Ccdc102a MGI:MGI:2686927|Ensembl:ENSMUSG00000063605|Vega:OTTMUSG00000027371 +234593 Ndrg4 MGI:MGI:2384590|Ensembl:ENSMUSG00000036564|Vega:OTTMUSG00000027408 +234594 Cnot1 MGI:MGI:2442402|Ensembl:ENSMUSG00000036550|Vega:OTTMUSG00000061794 +234595 Slc38a7 MGI:MGI:2679005|Ensembl:ENSMUSG00000036534|Vega:OTTMUSG00000022570 +234624 A330008L17Rik MGI:MGI:2443215|Ensembl:ENSMUSG00000052479 +234663 Dync1li2 MGI:MGI:107738|Ensembl:ENSMUSG00000035770|Vega:OTTMUSG00000061912 +234664 Nae1 MGI:MGI:2384561|Ensembl:ENSMUSG00000031878|Vega:OTTMUSG00000029165 +234669 Ces2b MGI:MGI:2448547|Ensembl:ENSMUSG00000050097|Vega:OTTMUSG00000027467 +234671 Ces2c MGI:MGI:2385905|Ensembl:ENSMUSG00000061825|Vega:OTTMUSG00000027466 +234673 Ces2e MGI:MGI:2443170|Ensembl:ENSMUSG00000031886|Vega:OTTMUSG00000061987 +234677 Ces4a MGI:MGI:2384581|Ensembl:ENSMUSG00000060560|Vega:OTTMUSG00000027469 +234678 D230025D16Rik MGI:MGI:2443049|Ensembl:ENSMUSG00000031889|Vega:OTTMUSG00000031385 +234683 Elmo3 MGI:MGI:2679007|Ensembl:ENSMUSG00000014791|Vega:OTTMUSG00000062045 +234684 Lrrc29 MGI:MGI:2443262|Ensembl:ENSMUSG00000041679|Vega:OTTMUSG00000060816 +234686 Fhod1 MGI:MGI:2679008|Ensembl:ENSMUSG00000014778|Vega:OTTMUSG00000029936 +234695 Carmil2 MGI:MGI:2685431|Ensembl:ENSMUSG00000050357|Vega:OTTMUSG00000062052 +234699 Edc4 MGI:MGI:2446249|Ensembl:ENSMUSG00000036270|Vega:OTTMUSG00000032525 +234700 Nrn1l MGI:MGI:2443642|Ensembl:ENSMUSG00000044287|Vega:OTTMUSG00000032524 +234703 Rpl10-ps2 MGI:MGI:3648679 +234723 Txnl4b MGI:MGI:2443724|Ensembl:ENSMUSG00000031723|Vega:OTTMUSG00000031603 +234724 Tat MGI:MGI:98487|Ensembl:ENSMUSG00000001670|Vega:OTTMUSG00000026257 +234725 Zfp612 MGI:MGI:2443465|Ensembl:ENSMUSG00000044676|Vega:OTTMUSG00000061889 +234728 Cmtr2 MGI:MGI:2384580|Ensembl:ENSMUSG00000046441|Vega:OTTMUSG00000048174 +234729 Vac14 MGI:MGI:2157980|Ensembl:ENSMUSG00000010936|Vega:OTTMUSG00000061893 +234730 Fuk MGI:MGI:1916071|Ensembl:ENSMUSG00000033703|Vega:OTTMUSG00000061895 +234733 Ddx19b MGI:MGI:2148251|Ensembl:ENSMUSG00000033658|Vega:OTTMUSG00000031896 +234734 Aars MGI:MGI:2384560|Ensembl:ENSMUSG00000031960|Vega:OTTMUSG00000031898 +234736 Rfwd3 MGI:MGI:2384584|Ensembl:ENSMUSG00000033596|Vega:OTTMUSG00000061896 +234740 Tmem231 MGI:MGI:2685024|Ensembl:ENSMUSG00000031951|Vega:OTTMUSG00000061806 +234757 BC024137 MGI:MGI:2670975 +234776 Atmin MGI:MGI:2682328|Ensembl:ENSMUSG00000047388|Vega:OTTMUSG00000037784 +234779 Plcg2 MGI:MGI:97616|Ensembl:ENSMUSG00000034330|Vega:OTTMUSG00000061722 +234788 Slc38a8 MGI:MGI:2685433|Ensembl:ENSMUSG00000034224|Vega:OTTMUSG00000031099 +234796 Klhl36 MGI:MGI:2385305|Ensembl:ENSMUSG00000031828|Vega:OTTMUSG00000061657 +234797 6430548M08Rik MGI:MGI:2443793|Ensembl:ENSMUSG00000031824|Vega:OTTMUSG00000023422 +234814 Mthfsd MGI:MGI:2679252|Ensembl:ENSMUSG00000031816|Vega:OTTMUSG00000027534 +234825 Klhdc4 MGI:MGI:2384569|Ensembl:ENSMUSG00000040263|Vega:OTTMUSG00000036984 +234836 Il17c MGI:MGI:2446486|Ensembl:ENSMUSG00000046108|Vega:OTTMUSG00000046183 +234839 Piezo1 MGI:MGI:3603204|Ensembl:ENSMUSG00000014444|Vega:OTTMUSG00000030164 +234847 Spg7 MGI:MGI:2385906|Ensembl:ENSMUSG00000000738|Vega:OTTMUSG00000022131 +234848 Rpl13-ps1 MGI:MGI:3649805 +234852 Chmp1a MGI:MGI:1920159|Ensembl:ENSMUSG00000000743|Vega:OTTMUSG00000036037 +234854 Cdk10 MGI:MGI:2448549|Ensembl:ENSMUSG00000033862|Vega:OTTMUSG00000061955 +234857 Spire2 MGI:MGI:2446256|Ensembl:ENSMUSG00000010154|Vega:OTTMUSG00000061961 +234863 6030466F02Rik MGI:MGI:3045390|Ensembl:ENSMUSG00000110599 +234865 Nup133 MGI:MGI:2442620|Ensembl:ENSMUSG00000039509|Vega:OTTMUSG00000062005 +234875 Ttc13 MGI:MGI:2384573|Ensembl:ENSMUSG00000037300|Vega:OTTMUSG00000031037 +234878 Map3k21 MGI:MGI:2385307|Ensembl:ENSMUSG00000031853|Vega:OTTMUSG00000061596 +234889 Gucy1a2 MGI:MGI:2660877|Ensembl:ENSMUSG00000041624|Vega:OTTMUSG00000061666 +234911 Mmp27 MGI:MGI:3039232|Ensembl:ENSMUSG00000070323|Vega:OTTMUSG00000031478 +234912 9230110C19Rik MGI:MGI:3045346|Ensembl:ENSMUSG00000053070|Vega:OTTMUSG00000062311 +234915 Cep126 MGI:MGI:2680221|Ensembl:ENSMUSG00000040729|Vega:OTTMUSG00000062312 +234959 Med17 MGI:MGI:2182585|Ensembl:ENSMUSG00000031935|Vega:OTTMUSG00000062253 +234964 Deup1 MGI:MGI:2443026|Ensembl:ENSMUSG00000039977|Vega:OTTMUSG00000023431 +234967 Slc36a4 MGI:MGI:2442595|Ensembl:ENSMUSG00000043885|Vega:OTTMUSG00000024294 +234988 Mbd3l2 MGI:MGI:2158460|Ensembl:ENSMUSG00000047508|Vega:OTTMUSG00000062574 +235028 Zfp426 MGI:MGI:1920248|Ensembl:ENSMUSG00000059475|Vega:OTTMUSG00000036855 +235033 Rdh8 MGI:MGI:2685028|Ensembl:ENSMUSG00000053773|Vega:OTTMUSG00000062999 +235036 Ppan MGI:MGI:2178445|Ensembl:ENSMUSG00000004100|Vega:OTTMUSG00000023850 +235040 Atg4d MGI:MGI:2444308|Ensembl:ENSMUSG00000002820|Vega:OTTMUSG00000063268 +235041 Kank2 MGI:MGI:2384568|Ensembl:ENSMUSG00000032194|Vega:OTTMUSG00000063571 +235043 Tmem205 MGI:MGI:3045495|Ensembl:ENSMUSG00000040883|Vega:OTTMUSG00000062319 +235044 Plppr2 MGI:MGI:2384575|Ensembl:ENSMUSG00000040563|Vega:OTTMUSG00000047453 +235047 Zfp809 MGI:MGI:2143362|Ensembl:ENSMUSG00000057982|Vega:OTTMUSG00000062355 +235048 Zfp599 MGI:MGI:2679006|Ensembl:ENSMUSG00000062794|Vega:OTTMUSG00000033650 +235050 Zfp810 MGI:MGI:2384563|Ensembl:ENSMUSG00000066829|Vega:OTTMUSG00000062358 +235067 Cypt4 MGI:MGI:1916573|Ensembl:ENSMUSG00000047995|Vega:OTTMUSG00000062544 +235072 Sept7 MGI:MGI:1335094|Ensembl:ENSMUSG00000001833|Vega:OTTMUSG00000062554 +235086 Igsf9b MGI:MGI:2685354|Ensembl:ENSMUSG00000034275|Vega:OTTMUSG00000032753 +235106 Ntm MGI:MGI:2446259|Ensembl:ENSMUSG00000059974|Vega:OTTMUSG00000023155 +235130 Adamts15 MGI:MGI:2449569|Ensembl:ENSMUSG00000033453|Vega:OTTMUSG00000062825 +235132 Zbtb44 MGI:MGI:1925123|Ensembl:ENSMUSG00000047412|Vega:OTTMUSG00000062827 +235134 Nfrkb MGI:MGI:2442410|Ensembl:ENSMUSG00000042185|Vega:OTTMUSG00000034118 +235135 Tmem45b MGI:MGI:2384574|Ensembl:ENSMUSG00000041737|Vega:OTTMUSG00000062879 +235169 Foxred1 MGI:MGI:2446262|Ensembl:ENSMUSG00000039048|Vega:OTTMUSG00000034114 +235180 Fez1 MGI:MGI:2670976|Ensembl:ENSMUSG00000032118|Vega:OTTMUSG00000034186 +235184 Msantd2 MGI:MGI:2384579|Ensembl:ENSMUSG00000042138|Vega:OTTMUSG00000060858 +235248 Olfr952 MGI:MGI:3030786|Ensembl:ENSMUSG00000058856|Vega:OTTMUSG00000062343 +235256 Olfr149 MGI:MGI:2660716|Ensembl:ENSMUSG00000062121|Vega:OTTMUSG00000062387 +235279 Gm4893 MGI:MGI:3648039 +235281 Scn3b MGI:MGI:1918882|Ensembl:ENSMUSG00000049281|Vega:OTTMUSG00000016755 +235283 Gramd1b MGI:MGI:1925037|Ensembl:ENSMUSG00000040111|Vega:OTTMUSG00000031780 +235293 Sc5d MGI:MGI:1353611|Ensembl:ENSMUSG00000032018|Vega:OTTMUSG00000063602 +235300 Tmem136 MGI:MGI:2685030|Ensembl:ENSMUSG00000048503|Vega:OTTMUSG00000063149 +235302 D630033O11Rik MGI:MGI:2685434|Vega:OTTMUSG00000060859 +235312 C1qtnf5 MGI:MGI:2385958|Ensembl:ENSMUSG00000079592|Vega:OTTMUSG00000020632 +235315 Rnf214 MGI:MGI:2444451|Ensembl:ENSMUSG00000042790|Vega:OTTMUSG00000034964 +235320 Zbtb16 MGI:MGI:103222|Ensembl:ENSMUSG00000066687|Vega:OTTMUSG00000063009 +235323 Usp28 MGI:MGI:2442293|Ensembl:ENSMUSG00000032267|Vega:OTTMUSG00000063013 +235327 Gm4894 MGI:MGI:3646156|Ensembl:ENSMUSG00000054156|Vega:OTTMUSG00000063015 +235330 Ttc12 MGI:MGI:2444588|Ensembl:ENSMUSG00000040219|Vega:OTTMUSG00000024805 +235339 Dlat MGI:MGI:2385311|Ensembl:ENSMUSG00000000168|Vega:OTTMUSG00000016493 +235344 Sik2 MGI:MGI:2445031|Ensembl:ENSMUSG00000037112|Vega:OTTMUSG00000042049 +235345 4833427G06Rik MGI:MGI:1921013|Ensembl:ENSMUSG00000032057|Vega:OTTMUSG00000063078 +235379 Gldn MGI:MGI:2388361|Ensembl:ENSMUSG00000046167|Vega:OTTMUSG00000027380 +235380 Dmxl2 MGI:MGI:2444630|Ensembl:ENSMUSG00000041268|Vega:OTTMUSG00000030270 +235386 Hykk MGI:MGI:2443139|Ensembl:ENSMUSG00000035878|Vega:OTTMUSG00000022644 +235392 Gm4895 MGI:MGI:3648582 +235402 Lingo1 MGI:MGI:1915522|Ensembl:ENSMUSG00000049556|Vega:OTTMUSG00000016697 +235406 Snx33 MGI:MGI:2443239|Ensembl:ENSMUSG00000032733|Vega:OTTMUSG00000063134 +235415 Cplx3 MGI:MGI:2384571|Ensembl:ENSMUSG00000039714|Vega:OTTMUSG00000063202 +235416 Lman1l MGI:MGI:2667537|Ensembl:ENSMUSG00000056271|Vega:OTTMUSG00000029965 +235431 Coro2b MGI:MGI:2444283|Ensembl:ENSMUSG00000041729|Vega:OTTMUSG00000023697 +235435 Lctl MGI:MGI:2183549|Ensembl:ENSMUSG00000032401|Vega:OTTMUSG00000028804 +235439 Herc1 MGI:MGI:2384589|Ensembl:ENSMUSG00000038664|Vega:OTTMUSG00000017312 +235441 Usp3 MGI:MGI:2152450|Ensembl:ENSMUSG00000032376|Vega:OTTMUSG00000023730 +235442 Rab8b MGI:MGI:2442982|Ensembl:ENSMUSG00000036943|Vega:OTTMUSG00000062649 +235459 Gtf2a2 MGI:MGI:1933289|Ensembl:ENSMUSG00000033543|Vega:OTTMUSG00000030858 +235461 Mindy2 MGI:MGI:2443086|Ensembl:ENSMUSG00000042444|Vega:OTTMUSG00000063625 +235469 Zfp280d MGI:MGI:2384583|Ensembl:ENSMUSG00000038535|Vega:OTTMUSG00000044709 +235472 Prtg MGI:MGI:2444710|Ensembl:ENSMUSG00000036030|Vega:OTTMUSG00000044731 +235493 Fam214a MGI:MGI:2387648|Ensembl:ENSMUSG00000034858|Vega:OTTMUSG00000062793 +235497 Leo1 MGI:MGI:2685031|Ensembl:ENSMUSG00000042487|Vega:OTTMUSG00000062803 +235503 Eef1a1-ps1 MGI:MGI:2388571 +235504 Slc17a5 MGI:MGI:1924105|Ensembl:ENSMUSG00000049624|Vega:OTTMUSG00000030755 +235505 Cd109 MGI:MGI:2445221|Ensembl:ENSMUSG00000046186|Vega:OTTMUSG00000036023 +235509 Gm4896 MGI:MGI:3643617 +235527 Plscr4 MGI:MGI:2143267|Ensembl:ENSMUSG00000032377|Vega:OTTMUSG00000022961 +235533 Gk5 MGI:MGI:2443336|Ensembl:ENSMUSG00000041440|Vega:OTTMUSG00000031738 +235534 Pxylp1 MGI:MGI:2442444|Ensembl:ENSMUSG00000043587|Vega:OTTMUSG00000027495 +235542 Ppp2r3a MGI:MGI:2442104|Ensembl:ENSMUSG00000043154|Vega:OTTMUSG00000048434 +235559 Topbp1 MGI:MGI:1920018|Ensembl:ENSMUSG00000032555|Vega:OTTMUSG00000048444 +235567 Dnajc13 MGI:MGI:2676368|Ensembl:ENSMUSG00000032560|Vega:OTTMUSG00000049291 +235574 Atp2c1 MGI:MGI:1889008|Ensembl:ENSMUSG00000032570|Vega:OTTMUSG00000042223 +235582 Glyctk MGI:MGI:2444085|Ensembl:ENSMUSG00000020258|Vega:OTTMUSG00000034701 +235584 Dusp7 MGI:MGI:2387100|Ensembl:ENSMUSG00000053716|Vega:OTTMUSG00000037684 +235587 Parp3 MGI:MGI:1891258|Ensembl:ENSMUSG00000023249|Vega:OTTMUSG00000033581 +235599 6430571L13Rik MGI:MGI:2445137|Ensembl:ENSMUSG00000037977|Vega:OTTMUSG00000030262 +235604 Camkv MGI:MGI:2384296|Ensembl:ENSMUSG00000032936|Vega:OTTMUSG00000050791 +235606 Apeh MGI:MGI:88041|Ensembl:ENSMUSG00000032590|Vega:OTTMUSG00000050818 +235610 Atrip MGI:MGI:1925349|Ensembl:ENSMUSG00000025646|Vega:OTTMUSG00000033648 +235611 Plxnb1 MGI:MGI:2154238|Ensembl:ENSMUSG00000053646|Vega:OTTMUSG00000021053 +235612 Fbxw19 MGI:MGI:3505706|Ensembl:ENSMUSG00000074061|Vega:OTTMUSG00000027446 +235623 Scap MGI:MGI:2135958|Ensembl:ENSMUSG00000032485|Vega:OTTMUSG00000023555 +235626 Setd2 MGI:MGI:1918177|Ensembl:ENSMUSG00000044791|Vega:OTTMUSG00000033479 +235627 Nbeal2 MGI:MGI:2448554|Ensembl:ENSMUSG00000056724|Vega:OTTMUSG00000032760 +235628 Prss42 MGI:MGI:2665280|Ensembl:ENSMUSG00000044664|Vega:OTTMUSG00000052495 +235631 Prss50 MGI:MGI:2447303|Ensembl:ENSMUSG00000048752|Vega:OTTMUSG00000052497 +235633 Als2cl MGI:MGI:2447532|Ensembl:ENSMUSG00000044037|Vega:OTTMUSG00000025999 +235634 Fam240a MGI:MGI:2685436|Ensembl:ENSMUSG00000096393|Vega:OTTMUSG00000052498 +235636 Rtp3 MGI:MGI:2446841|Ensembl:ENSMUSG00000066319|Vega:OTTMUSG00000052501 +235661 Dync1li1 MGI:MGI:2135610|Ensembl:ENSMUSG00000032435|Vega:OTTMUSG00000062857 +235674 Acaa1b MGI:MGI:3605455|Ensembl:ENSMUSG00000010651|Vega:OTTMUSG00000033525 +235682 Zfp445 MGI:MGI:2143340|Ensembl:ENSMUSG00000047036|Vega:OTTMUSG00000062784 +235712 Mrgpra2b MGI:MGI:3033098|Ensembl:ENSMUSG00000096719|Vega:OTTMUSG00000028717 +235779 Nlrp4g MGI:MGI:3700744 +235841 Obox4-ps23 MGI:MGI:3779446 +235854 Mrgpra4 MGI:MGI:3033100|Ensembl:ENSMUSG00000067173|Vega:OTTMUSG00000046581 +235858 Gm392 MGI:MGI:2685238 +235907 Zfp65 MGI:MGI:107769|Ensembl:ENSMUSG00000071281|Vega:OTTMUSG00000032930 +235952 Igkv4-57 MGI:MGI:2685035|IMGT/GENE-DB:IGKV4-57 +235956 Zfp825 MGI:MGI:2385315|Ensembl:ENSMUSG00000069208|Vega:OTTMUSG00000055590 +235966 Gm4898 MGI:MGI:3647354 +235973 A630095E13Rik MGI:MGI:3055869|Ensembl:ENSMUSG00000070313|Vega:OTTMUSG00000044744 +236010 Gm4899 MGI:MGI:3644090 +236047 Igkv4-74 MGI:MGI:3779447|IMGT/GENE-DB:IGKV4-74 +236069 Gm13238 MGI:MGI:3652104|Ensembl:ENSMUSG00000096233 +236082 Dhrsx MGI:MGI:2181510|Ensembl:ENSMUSG00000063897 +236149 Slc22a26 MGI:MGI:2385316|Ensembl:ENSMUSG00000053303|Vega:OTTMUSG00000028394 +236193 Zfp709 MGI:MGI:2384299|Ensembl:ENSMUSG00000056019|Vega:OTTMUSG00000047656 +236219 Tcstv3 MGI:MGI:2675349|Ensembl:ENSMUSG00000095821 +236266 Alms1 MGI:MGI:1934606|Ensembl:ENSMUSG00000063810|Vega:OTTMUSG00000024144 +236285 Lancl3 MGI:MGI:2443335|Ensembl:ENSMUSG00000047344|Vega:OTTMUSG00000016893 +236293 Slc22a29 MGI:MGI:3605624|Ensembl:ENSMUSG00000075044|Vega:OTTMUSG00000028422 +236294 Gm4900 MGI:MGI:3646967 +236312 Ifi209 MGI:MGI:2138243|Ensembl:ENSMUSG00000043263|Vega:OTTMUSG00000050198 +236366 5730507C01Rik MGI:MGI:1917882|Ensembl:ENSMUSG00000073197 +236427 Mageb10-ps MGI:MGI:2148174 +236428 BC026762 MGI:MGI:2652842 +236451 Phf11b MGI:MGI:3645789|Ensembl:ENSMUSG00000091649|Vega:OTTMUSG00000043571 +236479 Gm4903 MGI:MGI:3646001 +236509 Olfr366 MGI:MGI:3030200|Ensembl:ENSMUSG00000068947|Vega:OTTMUSG00000012206 +236511 Ago1 MGI:MGI:2446630|Ensembl:ENSMUSG00000041530|Vega:OTTMUSG00000009219 +236537 Zfp352 MGI:MGI:2387418|Ensembl:ENSMUSG00000070902|Vega:OTTMUSG00000007775 +236539 Phgdh MGI:MGI:1355330|Ensembl:ENSMUSG00000053398|Vega:OTTMUSG00000026317 +236546 AF067061 MGI:MGI:2681166|Ensembl:ENSMUSG00000095071|Vega:OTTMUSG00000042965 +236565 Gm4904 MGI:MGI:3648291 +236573 Gbp9 MGI:MGI:3605620|Ensembl:ENSMUSG00000029298|Vega:OTTMUSG00000053800 +236574 Smok2b MGI:MGI:3037705|Ensembl:ENSMUSG00000073457|Vega:OTTMUSG00000029533 +236576 Spry3 MGI:MGI:1345188|Ensembl:ENSMUSG00000061654 +236598 Rn28s1 - +236604 Pisd-ps1 MGI:MGI:3842428 +236643 Sytl5 MGI:MGI:2668451|Ensembl:ENSMUSG00000054453|Vega:OTTMUSG00000017464 +236663 H2al1j MGI:MGI:3643273|Ensembl:ENSMUSG00000069038|Vega:OTTMUSG00000016830 +236690 Nyx MGI:MGI:2448607|Ensembl:ENSMUSG00000051228|Vega:OTTMUSG00000016909 +236727 Slc9a7 MGI:MGI:2444530|Ensembl:ENSMUSG00000037341|Vega:OTTMUSG00000017060 +236732 Rbm10 MGI:MGI:2384310|Ensembl:ENSMUSG00000031060|Vega:OTTMUSG00000017091 +236733 Usp11 MGI:MGI:2384312|Ensembl:ENSMUSG00000031066|Vega:OTTMUSG00000017158 +236737 Gm1848 MGI:MGI:3037706 +236749 Gm4907 MGI:MGI:3648288|Ensembl:ENSMUSG00000068113|Vega:OTTMUSG00000016987 +236775 Gm4908 MGI:MGI:3645476 +236781 Gpr119 MGI:MGI:2668412|Ensembl:ENSMUSG00000051209|Vega:OTTMUSG00000017712 +236784 Olfr1320 MGI:MGI:3031154|Ensembl:ENSMUSG00000071764|Vega:OTTMUSG00000017800 +236785 Olfr1321 MGI:MGI:3031155|Ensembl:ENSMUSG00000067971|Vega:OTTMUSG00000017801 +236790 Ints6l MGI:MGI:2442593|Ensembl:ENSMUSG00000035967|Vega:OTTMUSG00000017533 +236792 Mmgt1 MGI:MGI:2384305|Ensembl:ENSMUSG00000061273|Vega:OTTMUSG00000017579 +236794 Slc9a6 MGI:MGI:2443511|Ensembl:ENSMUSG00000060681|Vega:OTTMUSG00000017578 +236798 Adgrg4 MGI:MGI:2685213|Ensembl:ENSMUSG00000053852|Vega:OTTMUSG00000017742 +236831 Gm4909 MGI:MGI:3648723 +236844 Gm4910 MGI:MGI:3645886 +236848 Tmem185a MGI:MGI:2448555|Ensembl:ENSMUSG00000073139|Vega:OTTMUSG00000017810 +236852 Magea10 MGI:MGI:3588211|Ensembl:ENSMUSG00000043453|Vega:OTTMUSG00000017850 +236866 Olfr1326-ps1 MGI:MGI:3031160 +236874 Gm14743 MGI:MGI:3705225|Ensembl:ENSMUSG00000079519|Vega:OTTMUSG00000017864 +236891 Mageb17-ps MGI:MGI:3643138 +236892 Gm4911 MGI:MGI:3643139 +236893 Gm4912 MGI:MGI:3643140 +236899 Pcyt1b MGI:MGI:2147987|Ensembl:ENSMUSG00000035246|Vega:OTTMUSG00000017967 +236900 Pdk3 MGI:MGI:2384308|Ensembl:ENSMUSG00000035232|Vega:OTTMUSG00000017968 +236904 Klhl15 MGI:MGI:1923400|Ensembl:ENSMUSG00000043929|Vega:OTTMUSG00000018085 +236914 Gm371 MGI:MGI:2685217 +236915 Arhgef9 MGI:MGI:2442233|Ensembl:ENSMUSG00000025656|Vega:OTTMUSG00000018030 +236920 Stard8 MGI:MGI:2448556|Ensembl:ENSMUSG00000031216|Vega:OTTMUSG00000018069 +236930 Ercc6l MGI:MGI:2654144|Ensembl:ENSMUSG00000051220|Vega:OTTMUSG00000018309 +236937 Vcp-rs MGI:MGI:894298 +236954 Gm379 MGI:MGI:2685225 +236983 Gm4913 MGI:MGI:3646629 +237008 Gm4914 MGI:MGI:3646569 +237009 Ube2dnl1 MGI:MGI:3646570|Ensembl:ENSMUSG00000050435|Vega:OTTMUSG00000018431 +237010 Klhl4 MGI:MGI:2442829|Ensembl:ENSMUSG00000025597|Vega:OTTMUSG00000018430 +237016 Gm4915 MGI:MGI:3647071 +237029 4932411N23Rik MGI:MGI:3045322|Ensembl:ENSMUSG00000058670|Vega:OTTMUSG00000018639 +237030 Gm4916 MGI:MGI:3643896 +237038 Nox1 MGI:MGI:2450016|Ensembl:ENSMUSG00000031257|Vega:OTTMUSG00000019159 +237048 Gm4917 MGI:MGI:3647066 +237052 Tceal1 MGI:MGI:2385317|Ensembl:ENSMUSG00000049536|Vega:OTTMUSG00000018724 +237073 Rbm41 MGI:MGI:2444923|Ensembl:ENSMUSG00000031433|Vega:OTTMUSG00000018843 +237082 Nxt2 MGI:MGI:2147914|Ensembl:ENSMUSG00000042271|Vega:OTTMUSG00000018737 +237091 Lhfpl1 MGI:MGI:1891214|Ensembl:ENSMUSG00000041700|Vega:OTTMUSG00000018892 +237096 Gm4918 MGI:MGI:3644582 +237107 Gnl3l MGI:MGI:2448557|Ensembl:ENSMUSG00000025266|Vega:OTTMUSG00000019232 +237116 Gm4919 MGI:MGI:3644910 +237175 Adgrg2 MGI:MGI:2446854|Ensembl:ENSMUSG00000031298|Vega:OTTMUSG00000019584 +237178 Ppef1 MGI:MGI:1097157|Ensembl:ENSMUSG00000062168|Vega:OTTMUSG00000019590 +237211 Fancb MGI:MGI:2448558|Ensembl:ENSMUSG00000047757|Vega:OTTMUSG00000019556 +237213 Glra2 MGI:MGI:95748|Ensembl:ENSMUSG00000018589|Vega:OTTMUSG00000019555 +237221 Gemin8 MGI:MGI:2384300|Ensembl:ENSMUSG00000040621|Vega:OTTMUSG00000019540 +237222 Ofd1 MGI:MGI:1350328|Ensembl:ENSMUSG00000040586|Vega:OTTMUSG00000019549 +237246 BC022960 MGI:MGI:2670977 +237252 Gm4921 MGI:MGI:3779448 +237253 Lrp11 MGI:MGI:2442989|Ensembl:ENSMUSG00000019796|Vega:OTTMUSG00000032764 +237256 Zc3h12d MGI:MGI:3045313|Ensembl:ENSMUSG00000039981 +237300 Gm4922 MGI:MGI:3644318|Ensembl:ENSMUSG00000044624|Vega:OTTMUSG00000063681 +237310 Il22ra2 MGI:MGI:2665114|Ensembl:ENSMUSG00000039760|Vega:OTTMUSG00000028020 +237313 Il20ra MGI:MGI:3605069|Ensembl:ENSMUSG00000020007|Vega:OTTMUSG00000063784 +237320 Aldh8a1 MGI:MGI:2653900|Ensembl:ENSMUSG00000037542|Vega:OTTMUSG00000028021 +237336 Tbpl1 MGI:MGI:1339946|Ensembl:ENSMUSG00000071359|Vega:OTTMUSG00000028051 +237339 L3mbtl3 MGI:MGI:2143628|Ensembl:ENSMUSG00000039089|Vega:OTTMUSG00000037127 +237353 Sh3rf3 MGI:MGI:2444637|Ensembl:ENSMUSG00000037990|Vega:OTTMUSG00000033616 +237360 Adamts14 MGI:MGI:2179942|Ensembl:ENSMUSG00000059901|Vega:OTTMUSG00000031948 +237361 Rpl27a-ps1 MGI:MGI:3645354 +237362 Npffr1 MGI:MGI:2685082|Ensembl:ENSMUSG00000020090|Vega:OTTMUSG00000047708 +237387 Lrrc3 MGI:MGI:2447899|Ensembl:ENSMUSG00000051652|Vega:OTTMUSG00000020516 +237397 C2cd4c MGI:MGI:2685084|Ensembl:ENSMUSG00000045912 +237400 Mex3d MGI:MGI:2681847|Ensembl:ENSMUSG00000048696|Vega:OTTMUSG00000019122 +237403 Lingo3 MGI:MGI:3609246|Ensembl:ENSMUSG00000051067 +237411 Zfp938 MGI:MGI:3621440|Ensembl:ENSMUSG00000062931|Vega:OTTMUSG00000024190 +237412 Gm4924 MGI:MGI:3643133|Ensembl:ENSMUSG00000073427|Vega:OTTMUSG00000060245 +237422 Ric8b MGI:MGI:2682307|Ensembl:ENSMUSG00000035620|Vega:OTTMUSG00000063527 +237433 Gm4925 MGI:MGI:3643371 +237436 Gas2l3 MGI:MGI:1918780|Ensembl:ENSMUSG00000074802 +237459 Cdk17 MGI:MGI:97517|Ensembl:ENSMUSG00000020015|Vega:OTTMUSG00000063859 +237465 Ccdc38 MGI:MGI:2444738|Ensembl:ENSMUSG00000036168|Vega:OTTMUSG00000030958 +237500 Tmtc3 MGI:MGI:3036255|Ensembl:ENSMUSG00000036676|Vega:OTTMUSG00000034150 +237504 Rassf9 MGI:MGI:2384307|Ensembl:ENSMUSG00000044921|Vega:OTTMUSG00000036122 +237523 Ptprq MGI:MGI:1096349|Ensembl:ENSMUSG00000035916|Vega:OTTMUSG00000050771 +237542 Osbpl8 MGI:MGI:2443807|Ensembl:ENSMUSG00000020189 +237553 Trhde MGI:MGI:2384311|Ensembl:ENSMUSG00000050663|Vega:OTTMUSG00000025680 +237558 Myrfl MGI:MGI:2685085|Ensembl:ENSMUSG00000034057 +237560 Lrrc10 MGI:MGI:2448063|Ensembl:ENSMUSG00000060187 +237611 Stac3 MGI:MGI:3606571|Ensembl:ENSMUSG00000040287|Vega:OTTMUSG00000027709 +237615 Ankrd52 MGI:MGI:2444029|Ensembl:ENSMUSG00000014498|Vega:OTTMUSG00000035846 +237625 Pla2g3 MGI:MGI:2444945|Ensembl:ENSMUSG00000034579|Vega:OTTMUSG00000005026 +237636 Npc1l1 MGI:MGI:2685089|Ensembl:ENSMUSG00000020447|Vega:OTTMUSG00000000776 +237694 4932414J04Rik MGI:MGI:3605619|Ensembl:ENSMUSG00000078962 +237711 Eml6 MGI:MGI:2442895|Ensembl:ENSMUSG00000044072|Vega:OTTMUSG00000005340 +237716 Gpr75 MGI:MGI:2441843|Ensembl:ENSMUSG00000043999|Vega:OTTMUSG00000005353 +237730 Fbll1 MGI:MGI:3034689|Ensembl:ENSMUSG00000051062|Vega:OTTMUSG00000005414 +237749 Gm4926 MGI:MGI:3646427|Ensembl:ENSMUSG00000086909 +237754 Btnl9 MGI:MGI:2442439|Ensembl:ENSMUSG00000040283|Vega:OTTMUSG00000005543 +237758 Zfp454 MGI:MGI:2679253|Ensembl:ENSMUSG00000048728|Vega:OTTMUSG00000007886 +237759 Col23a1 MGI:MGI:2653243|Ensembl:ENSMUSG00000063564|Vega:OTTMUSG00000005601 +237761 Sowaha MGI:MGI:2687280|Ensembl:ENSMUSG00000044352|Vega:OTTMUSG00000005638 +237769 Gm12258 MGI:MGI:3651534 +237775 Zfp867 MGI:MGI:2681848|Ensembl:ENSMUSG00000054519|Vega:OTTMUSG00000005799 +237781 Mief2 MGI:MGI:2144199|Ensembl:ENSMUSG00000018599|Vega:OTTMUSG00000007763 +237782 Smcr8 MGI:MGI:2444720|Ensembl:ENSMUSG00000049323|Vega:OTTMUSG00000007770 +237806 Dnah9 MGI:MGI:1289279|Ensembl:ENSMUSG00000056752|Vega:OTTMUSG00000005907 +237823 Pfas MGI:MGI:2684864|Ensembl:ENSMUSG00000020899|Vega:OTTMUSG00000005962 +237831 Slc13a5 MGI:MGI:3037150|Ensembl:ENSMUSG00000020805|Vega:OTTMUSG00000006104 +237847 Rtn4rl1 MGI:MGI:2661375|Ensembl:ENSMUSG00000045287|Vega:OTTMUSG00000006197 +237858 Tusc5 MGI:MGI:3029307|Ensembl:ENSMUSG00000046275|Vega:OTTMUSG00000006237 +237859 Nsrp1 MGI:MGI:2144305|Ensembl:ENSMUSG00000037958|Vega:OTTMUSG00000006241 +237860 Ssh2 MGI:MGI:2679255|Ensembl:ENSMUSG00000037926|Vega:OTTMUSG00000006248 +237868 Sarm1 MGI:MGI:2136419|Ensembl:ENSMUSG00000050132|Vega:OTTMUSG00000000147 +237877 Atad5 MGI:MGI:2442925|Ensembl:ENSMUSG00000017550|Vega:OTTMUSG00000000189 +237880 1700071K01Rik MGI:MGI:3588264 +237886 Slfn9 MGI:MGI:2445121|Ensembl:ENSMUSG00000069793|Vega:OTTMUSG00000000923 +237887 Slfn10-ps MGI:MGI:3512288|Ensembl:ENSMUSG00000072621 +237890 Slfn14 MGI:MGI:2684866|Ensembl:ENSMUSG00000082101|Vega:OTTMUSG00000000927 +237891 Gas2l2 MGI:MGI:3652048|Ensembl:ENSMUSG00000020686|Vega:OTTMUSG00000000934 +237898 Usp32 MGI:MGI:2144475|Ensembl:ENSMUSG00000000804|Vega:OTTMUSG00000001019 +237911 Brip1 MGI:MGI:2442836|Ensembl:ENSMUSG00000034329|Vega:OTTMUSG00000001045 +237926 Rsad1 MGI:MGI:3039628|Ensembl:ENSMUSG00000039096|Vega:OTTMUSG00000002016 +237928 Phospho1 MGI:MGI:2447348|Ensembl:ENSMUSG00000050860|Vega:OTTMUSG00000001750 +237930 Ttll6 MGI:MGI:2683461|Ensembl:ENSMUSG00000038756|Vega:OTTMUSG00000001959 +237934 Krt39 MGI:MGI:3588208|Ensembl:ENSMUSG00000064165|Vega:OTTMUSG00000004991 +237940 Aoc2 MGI:MGI:2668431|Ensembl:ENSMUSG00000078651|Vega:OTTMUSG00000002792 +237943 Gpatch8 MGI:MGI:1918667|Ensembl:ENSMUSG00000034621|Vega:OTTMUSG00000002856 +237954 Lrrc37a MGI:MGI:2685097|Ensembl:ENSMUSG00000078632|Vega:OTTMUSG00000002842 +237958 Sppl2c MGI:MGI:3045264|Ensembl:ENSMUSG00000049506|Vega:OTTMUSG00000003150 +237979 Sdk2 MGI:MGI:2443847|Ensembl:ENSMUSG00000041592|Vega:OTTMUSG00000003805 +237987 Otop2 MGI:MGI:2388365|Ensembl:ENSMUSG00000050201|Vega:OTTMUSG00000003749 +237988 Cdr2l MGI:MGI:2684867|Ensembl:ENSMUSG00000050910|Vega:OTTMUSG00000003795 +238011 Enpp7 MGI:MGI:3027917|Ensembl:ENSMUSG00000046697|Vega:OTTMUSG00000003976 +238021 Fscn2 MGI:MGI:2443337|Ensembl:ENSMUSG00000025380|Vega:OTTMUSG00000004147 +238023 Hexdc MGI:MGI:3605542|Ensembl:ENSMUSG00000039307|Vega:OTTMUSG00000004295 +238024 Fn3krp MGI:MGI:2679256|Ensembl:ENSMUSG00000039253|Vega:OTTMUSG00000004676 +238037 Wdcp MGI:MGI:3040699|Ensembl:ENSMUSG00000051721 +238049 Gm4927 MGI:MGI:3779449 +238055 Apob MGI:MGI:88052|Ensembl:ENSMUSG00000020609|Vega:OTTMUSG00000035465 +238057 Gdf7 MGI:MGI:95690|Ensembl:ENSMUSG00000037660 +238074 Gm4928 MGI:MGI:3644549 +238076 Kcns3 MGI:MGI:1098804|Ensembl:ENSMUSG00000043673 +238091 Gm4929 MGI:MGI:3645941 +238123 Cog5 MGI:MGI:2145130|Ensembl:ENSMUSG00000035933 +238130 Dock4 MGI:MGI:1918006|Ensembl:ENSMUSG00000035954 +238161 Akap6 MGI:MGI:3050566|Ensembl:ENSMUSG00000061603 +238199 Gm4930 MGI:MGI:3644853 +238205 Lrfn5 MGI:MGI:2144814|Ensembl:ENSMUSG00000035653|Vega:OTTMUSG00000027631 +238217 Rpl10l MGI:MGI:3647985|Ensembl:ENSMUSG00000060499|Vega:OTTMUSG00000043585 +238247 Arid4a MGI:MGI:2444354|Ensembl:ENSMUSG00000048118|Vega:OTTMUSG00000017260 +238252 Gpr135 MGI:MGI:2676315|Ensembl:ENSMUSG00000043398 +238257 Tmem30b MGI:MGI:2442082|Ensembl:ENSMUSG00000034435 +238266 Syt16 MGI:MGI:2673872|Ensembl:ENSMUSG00000044912 +238271 Kcnh5 MGI:MGI:3584508|Ensembl:ENSMUSG00000034402 +238276 Akap5 MGI:MGI:2685104|Ensembl:ENSMUSG00000021057|Vega:OTTMUSG00000016317 +238317 Elmsan1 MGI:MGI:2685106|Ensembl:ENSMUSG00000042507|Vega:OTTMUSG00000017439 +238323 Rps6kl1 MGI:MGI:2443413|Ensembl:ENSMUSG00000019235 +238328 Vash1 MGI:MGI:2442543|Ensembl:ENSMUSG00000021256|Vega:OTTMUSG00000029994 +238330 Irf2bpl MGI:MGI:2442463|Ensembl:ENSMUSG00000034168 +238331 Zdhhc22 MGI:MGI:2685108|Ensembl:ENSMUSG00000048483 +238333 Samd15 MGI:MGI:2685109|Ensembl:ENSMUSG00000090812|Vega:OTTMUSG00000043613 +238377 Gpr68 MGI:MGI:2441763|Ensembl:ENSMUSG00000047415|Vega:OTTMUSG00000024497 +238384 Slc24a4 MGI:MGI:2447362|Ensembl:ENSMUSG00000041771|Vega:OTTMUSG00000033883 +238386 Btbd7 MGI:MGI:1917858|Ensembl:ENSMUSG00000041702 +238393 Serpina3f MGI:MGI:2182838|Ensembl:ENSMUSG00000066363|Vega:OTTMUSG00000027578 +238395 Serpina3j MGI:MGI:2182843|Ensembl:ENSMUSG00000079013|Vega:OTTMUSG00000035426 +238405 Adam6b MGI:MGI:2444636|Ensembl:ENSMUSG00000051804|Vega:OTTMUSG00000051587 +238406 Adam6a MGI:MGI:2676316|Ensembl:ENSMUSG00000043945|Vega:OTTMUSG00000051592 +238412 Ighv2-3 MGI:MGI:4439872|IMGT/GENE-DB:IGHV2-3 +238418 Ighv14-3 MGI:MGI:4439764|IMGT/GENE-DB:IGHV14-3 +238427 Ighv6-6 MGI:MGI:4439619|IMGT/GENE-DB:IGHV6-6 +238428 Ighv1-2 MGI:MGI:4439924|IMGT/GENE-DB:IGHV1-2 +238440 LOC238440 - +238447 Igha MGI:MGI:96444|IMGT/GENE-DB:IGHA +238448 Ighv1-62-2 MGI:MGI:3644968|IMGT/GENE-DB:IGHV1-62-2 +238455 Macc1 MGI:MGI:2685113|Ensembl:ENSMUSG00000041886|Vega:OTTMUSG00000045335 +238463 Tubal3 MGI:MGI:3588215|Ensembl:ENSMUSG00000021216 +238505 Mtr MGI:MGI:894292|Ensembl:ENSMUSG00000021311 +238555 Btn2a2 MGI:MGI:3606486|Ensembl:ENSMUSG00000053216|Vega:OTTMUSG00000000552 +238564 Mylk4 MGI:MGI:3643758|Ensembl:ENSMUSG00000044951|Vega:OTTMUSG00000000690 +238568 Serpinb6d MGI:MGI:2667783|Ensembl:ENSMUSG00000047889|Vega:OTTMUSG00000000712 +238662 Spata31d1b MGI:MGI:3646080|Ensembl:ENSMUSG00000091311 +238663 Spata31d1d MGI:MGI:3045260|Ensembl:ENSMUSG00000043986|Vega:OTTMUSG00000044381 +238673 Zfp367 MGI:MGI:2442266|Ensembl:ENSMUSG00000044934|Vega:OTTMUSG00000027754 +238678 Gm4935 MGI:MGI:3779450 +238680 Cntnap3 MGI:MGI:3588199|Ensembl:ENSMUSG00000033063 +238683 Spata31d1c MGI:MGI:3588241|Ensembl:ENSMUSG00000074849 +238690 Zfp458 MGI:MGI:3040691|Ensembl:ENSMUSG00000055480 +238692 Zfp874a MGI:MGI:3040703|Ensembl:ENSMUSG00000069206|Vega:OTTMUSG00000042792 +238693 Zfp58 MGI:MGI:99205|Ensembl:ENSMUSG00000071291|Vega:OTTMUSG00000036775 +238722 Zfp72 MGI:MGI:3033356|Ensembl:ENSMUSG00000069184 +238725 Gpr150 MGI:MGI:2441872|Ensembl:ENSMUSG00000045509|Vega:OTTMUSG00000017555 +238726 Fam81b MGI:MGI:2685122|Ensembl:ENSMUSG00000109228|Vega:OTTMUSG00000059342 +238756 Gm4936 MGI:MGI:3648727 +238799 Tnpo1 MGI:MGI:2681523|Ensembl:ENSMUSG00000009470|Vega:OTTMUSG00000024774 +238803 Zfp366 MGI:MGI:2178429|Ensembl:ENSMUSG00000050919|Vega:OTTMUSG00000027698 +238829 Cldn34b3 MGI:MGI:3648293|Ensembl:ENSMUSG00000071738|Vega:OTTMUSG00000017780 +238831 Ppwd1 MGI:MGI:2443069|Ensembl:ENSMUSG00000021713 +238836 Gm4938 MGI:MGI:3645099 +238871 Pde4d MGI:MGI:99555|Ensembl:ENSMUSG00000021699|Vega:OTTMUSG00000031955 +238875 Gapt MGI:MGI:3608341|Ensembl:ENSMUSG00000046006 +238880 Actbl2 MGI:MGI:2444552|Ensembl:ENSMUSG00000055194|Vega:OTTMUSG00000054405 +238896 Cdc20b MGI:MGI:3644472|Ensembl:ENSMUSG00000078926|Vega:OTTMUSG00000042682 +238939 Gm281 MGI:MGI:2685127|Ensembl:ENSMUSG00000084902|Vega:OTTMUSG00000033781 +238963 Gm4939 MGI:MGI:3646780 +238988 Erc2 MGI:MGI:1098749|Ensembl:ENSMUSG00000040640|Vega:OTTMUSG00000060924 +239017 Ogdhl MGI:MGI:3616088|Ensembl:ENSMUSG00000021913 +239027 Arhgap22 MGI:MGI:2443418|Ensembl:ENSMUSG00000063506|Vega:OTTMUSG00000023066 +239029 Antxrl MGI:MGI:1925726|Ensembl:ENSMUSG00000047441 +239036 4930596D02Rik MGI:MGI:3588288|Ensembl:ENSMUSG00000041068|Vega:OTTMUSG00000047976 +239037 Lrit1 MGI:MGI:2385320|Ensembl:ENSMUSG00000041044|Vega:OTTMUSG00000027933 +239038 Lrit2 MGI:MGI:2444885|Ensembl:ENSMUSG00000043418 +239081 Tlr11 MGI:MGI:3045226|Ensembl:ENSMUSG00000051969|Vega:OTTMUSG00000044436 +239083 Ccnb1ip1 MGI:MGI:2685134|Ensembl:ENSMUSG00000071470 +239096 Cdh24 MGI:MGI:1928330|Ensembl:ENSMUSG00000059674 +239099 Homez MGI:MGI:2678023|Ensembl:ENSMUSG00000057156|Vega:OTTMUSG00000032805 +239102 Zfhx2 MGI:MGI:2686934|Ensembl:ENSMUSG00000040721|Vega:OTTMUSG00000041076 +239114 Il17d MGI:MGI:2446510|Ensembl:ENSMUSG00000050222 +239122 Setdb2 MGI:MGI:2685139|Ensembl:ENSMUSG00000071350|Vega:OTTMUSG00000033346 +239126 C1qtnf9 MGI:MGI:3045252|Ensembl:ENSMUSG00000071347|Vega:OTTMUSG00000027848 +239133 Dleu7 MGI:MGI:2447771|Ensembl:ENSMUSG00000048281 +239134 Gucy1b2 MGI:MGI:2660873|Ensembl:ENSMUSG00000021933|Vega:OTTMUSG00000019627 +239157 Pnma2 MGI:MGI:2444129|Ensembl:ENSMUSG00000046204|Vega:OTTMUSG00000035206 +239167 Synb MGI:MGI:3045308|Ensembl:ENSMUSG00000047977|Vega:OTTMUSG00000035207 +239170 Fam160b2 MGI:MGI:3036290|Ensembl:ENSMUSG00000022095 +239188 Enox1 MGI:MGI:2444896|Ensembl:ENSMUSG00000022012 +239217 Kctd12 MGI:MGI:2145823|Ensembl:ENSMUSG00000098557|Vega:OTTMUSG00000044960 +239250 Slitrk6 MGI:MGI:2443198|Ensembl:ENSMUSG00000045871 +239273 Abcc4 MGI:MGI:2443111|Ensembl:ENSMUSG00000032849 +239283 Oxgr1 MGI:MGI:2685145|Ensembl:ENSMUSG00000044819 +239318 Plcxd3 MGI:MGI:2442605|Ensembl:ENSMUSG00000049148|Vega:OTTMUSG00000027967 +239319 Card6 MGI:MGI:3032959|Ensembl:ENSMUSG00000041849|Vega:OTTMUSG00000029909 +239336 Rxfp3 MGI:MGI:2441827|Ensembl:ENSMUSG00000060735|Vega:OTTMUSG00000044336 +239337 Adamts12 MGI:MGI:2146046|Ensembl:ENSMUSG00000047497 +239338 Gm4940 MGI:MGI:3644793 +239364 Tspyl5 MGI:MGI:2442458|Ensembl:ENSMUSG00000038984 +239368 Erich5 MGI:MGI:2447772|Ensembl:ENSMUSG00000044726 +239393 Lrp12 MGI:MGI:2443132|Ensembl:ENSMUSG00000022305|Vega:OTTMUSG00000023989 +239405 Rspo2 MGI:MGI:1922667|Ensembl:ENSMUSG00000051920 +239408 Tmem74 MGI:MGI:2443417|Ensembl:ENSMUSG00000054409 +239410 A930017M01Rik MGI:MGI:2685151 +239420 Csmd3 MGI:MGI:2386403|Ensembl:ENSMUSG00000022311|Vega:OTTMUSG00000033335 +239435 Aard MGI:MGI:2181621|Ensembl:ENSMUSG00000068522|Vega:OTTMUSG00000043331 +239436 Slc30a8 MGI:MGI:2442682|Ensembl:ENSMUSG00000022315|Vega:OTTMUSG00000024040 +239447 Colec10 MGI:MGI:3606482|Ensembl:ENSMUSG00000038591 +239463 Fam83a MGI:MGI:2447773|Ensembl:ENSMUSG00000051225|Vega:OTTMUSG00000034301 +239502 Gm4942 MGI:MGI:3648683 +239510 Phf20l1 MGI:MGI:2444412|Ensembl:ENSMUSG00000072501 +239528 Ago2 MGI:MGI:2446632|Ensembl:ENSMUSG00000036698|Vega:OTTMUSG00000040103 +239530 Gpr20 MGI:MGI:2441803|Ensembl:ENSMUSG00000045281|Vega:OTTMUSG00000029052 +239546 Zfp647 MGI:MGI:3052806|Ensembl:ENSMUSG00000054967 +239552 Apol8 MGI:MGI:2444921|Ensembl:ENSMUSG00000056656 +239554 Foxred2 MGI:MGI:106315|Ensembl:ENSMUSG00000016552|Vega:OTTMUSG00000028122 +239555 Mief1 MGI:MGI:2146020|Ensembl:ENSMUSG00000022412 +239556 Cacna1i MGI:MGI:2178051|Ensembl:ENSMUSG00000022416|Vega:OTTMUSG00000034511 +239559 A4galt MGI:MGI:3512453|Ensembl:ENSMUSG00000047878 +239570 Ttc38 MGI:MGI:2146198|Ensembl:ENSMUSG00000035944|Vega:OTTMUSG00000033311 +239591 Ttll8 MGI:MGI:1922902|Ensembl:ENSMUSG00000022388|Vega:OTTMUSG00000023602 +239606 Slc2a13 MGI:MGI:2146030|Ensembl:ENSMUSG00000036298|Vega:OTTMUSG00000020865 +239611 Muc19 MGI:MGI:2676278 +239618 Pdzrn4 MGI:MGI:3056996|Ensembl:ENSMUSG00000036218 +239647 Pced1b MGI:MGI:2446270|Ensembl:ENSMUSG00000044250 +239650 Ccdc184 MGI:MGI:2146066|Ensembl:ENSMUSG00000029875 +239652 Zfp641 MGI:MGI:2442788|Ensembl:ENSMUSG00000022987 +239659 C1ql4 MGI:MGI:3579909|Ensembl:ENSMUSG00000001076 +239667 Dip2b MGI:MGI:2145977|Ensembl:ENSMUSG00000023026|Vega:OTTMUSG00000019849 +239673 Krt90 MGI:MGI:3045312|Ensembl:ENSMUSG00000048699|Vega:OTTMUSG00000028034 +239691 AU021092 MGI:MGI:2146559|Ensembl:ENSMUSG00000051669|Vega:OTTMUSG00000028134 +239706 Mettl22 MGI:MGI:2384301|Ensembl:ENSMUSG00000039345|Vega:OTTMUSG00000023115 +239719 Mkl2 MGI:MGI:3050795|Ensembl:ENSMUSG00000009569|Vega:OTTMUSG00000026951 +239731 Rimbp3 MGI:MGI:2685449|Ensembl:ENSMUSG00000071636|Vega:OTTMUSG00000024840 +239739 Lamp3 MGI:MGI:2441659|Ensembl:ENSMUSG00000041247 +239743 Klhl6 MGI:MGI:2686922|Ensembl:ENSMUSG00000043008|Vega:OTTMUSG00000035230 +239759 Liph MGI:MGI:2388029|Ensembl:ENSMUSG00000044626 +239760 Gm4943 MGI:MGI:3645174 +239766 Rtp1 MGI:MGI:2685450|Ensembl:ENSMUSG00000033383 +239789 Gmnc MGI:MGI:2685452|Ensembl:ENSMUSG00000068428 +239790 Ostn MGI:MGI:2677164|Ensembl:ENSMUSG00000052276|Vega:OTTMUSG00000028412 +239796 Mb21d2 MGI:MGI:1917028|Ensembl:ENSMUSG00000051065 +239827 Pigz MGI:MGI:2443822|Ensembl:ENSMUSG00000045625|Vega:OTTMUSG00000025435 +239833 Lmln MGI:MGI:2444736|Ensembl:ENSMUSG00000022802|Vega:OTTMUSG00000026934 +239839 Ccdc14 MGI:MGI:2443448|Ensembl:ENSMUSG00000022833 +239845 Gpr156 MGI:MGI:2653880|Ensembl:ENSMUSG00000046961 +239849 Cd200r4 MGI:MGI:3036289|Ensembl:ENSMUSG00000062082|Vega:OTTMUSG00000014979 +239852 Zpld1 MGI:MGI:2443415|Ensembl:ENSMUSG00000064310|Vega:OTTMUSG00000025160 +239853 Adgrg7 MGI:MGI:2441732|Ensembl:ENSMUSG00000022755|Vega:OTTMUSG00000025267 +239857 Cadm2 MGI:MGI:2442722|Ensembl:ENSMUSG00000064115|Vega:OTTMUSG00000017090 +239931 Cldn17 MGI:MGI:2652030|Ensembl:ENSMUSG00000055811|Vega:OTTMUSG00000019870 +239932 Krtap24-1 MGI:MGI:2685158|Ensembl:ENSMUSG00000050239 +239933 Krtap27-1 MGI:MGI:3646229|Ensembl:ENSMUSG00000090515|Vega:OTTMUSG00000044995 +239985 Arid1b MGI:MGI:1926129|Ensembl:ENSMUSG00000069729|Vega:OTTMUSG00000023805 +240023 Pnldc1 MGI:MGI:2685159|Ensembl:ENSMUSG00000073460 +240025 Dact2 MGI:MGI:1920347|Ensembl:ENSMUSG00000048826 +240028 Lnpep MGI:MGI:2387123|Ensembl:ENSMUSG00000023845 +240034 Zfp760 MGI:MGI:2679257|Ensembl:ENSMUSG00000067928 +240038 Zfp994 MGI:MGI:3643318|Ensembl:ENSMUSG00000096433 +240041 Zfp945 MGI:MGI:2445132|Ensembl:ENSMUSG00000059142|Vega:OTTMUSG00000032978 +240047 Mmp25 MGI:MGI:2443938|Ensembl:ENSMUSG00000023903 +240054 D630044L22Rik MGI:MGI:3709661 +240055 Neurl1b MGI:MGI:3643092|Ensembl:ENSMUSG00000034413|Vega:OTTMUSG00000043222 +240057 Syngap1 MGI:MGI:3039785|Ensembl:ENSMUSG00000067629|Vega:OTTMUSG00000049838 +240058 Cpne5 MGI:MGI:2385908|Ensembl:ENSMUSG00000024008|Vega:OTTMUSG00000028956 +240063 Zfp811 MGI:MGI:2682944|Ensembl:ENSMUSG00000055202|Vega:OTTMUSG00000056163 +240064 Zfp799 MGI:MGI:2443934|Ensembl:ENSMUSG00000095253|Vega:OTTMUSG00000056165 +240066 Zfp870 MGI:MGI:3029586|Ensembl:ENSMUSG00000095325 +240067 Zfp952 MGI:MGI:2441928|Ensembl:ENSMUSG00000053390|Vega:OTTMUSG00000031505 +240068 Zfp563 MGI:MGI:2677168|Ensembl:ENSMUSG00000067424|Vega:OTTMUSG00000033106 +240069 Morc2b MGI:MGI:3045293|Ensembl:ENSMUSG00000048602|Vega:OTTMUSG00000033000 +240084 Cchcr1 MGI:MGI:2385321|Ensembl:ENSMUSG00000040312|Vega:OTTMUSG00000037236 +240087 Mdc1 MGI:MGI:3525201|Ensembl:ENSMUSG00000061607|Vega:OTTMUSG00000037407 +240095 H2-M5 MGI:MGI:95917|Ensembl:ENSMUSG00000024459|Vega:OTTMUSG00000014934 +240110 Gm4945 MGI:MGI:3647512 +240117 Gm4946 MGI:MGI:3647513 +240119 St6gal2 MGI:MGI:2445190|Ensembl:ENSMUSG00000024172|Vega:OTTMUSG00000028471 +240120 Zfp119b MGI:MGI:2385323|Ensembl:ENSMUSG00000062101|Vega:OTTMUSG00000045090 +240121 Fsd1 MGI:MGI:1934858|Ensembl:ENSMUSG00000011589 +240131 Lrrc30 MGI:MGI:2685172|Ensembl:ENSMUSG00000073375 +240156 Gm4947 MGI:MGI:3644856 +240160 Gm4948 MGI:MGI:3645145 +240168 Rasgrp3 MGI:MGI:3028579|Ensembl:ENSMUSG00000071042 +240174 Thada MGI:MGI:3039623|Ensembl:ENSMUSG00000024251 +240185 Jcad MGI:MGI:2685174|Ensembl:ENSMUSG00000033960 +240186 Zfp438 MGI:MGI:2444919|Ensembl:ENSMUSG00000050945 +240215 Slc4a9 MGI:MGI:2443384|Ensembl:ENSMUSG00000024485 +240216 E230025N22Rik MGI:MGI:3687212|Ensembl:ENSMUSG00000044719|Vega:OTTMUSG00000033632 +240219 Gm4949 MGI:MGI:3646890 +240239 Gpr151 MGI:MGI:2441887|Ensembl:ENSMUSG00000042816 +240255 Ythdc2 MGI:MGI:2448561|Ensembl:ENSMUSG00000034653|Vega:OTTMUSG00000055570 +240261 Ccdc112 MGI:MGI:1918800|Ensembl:ENSMUSG00000071855 +240263 Fem1c MGI:MGI:2444737|Ensembl:ENSMUSG00000033319|Vega:OTTMUSG00000042430 +240283 Dmxl1 MGI:MGI:2443926|Ensembl:ENSMUSG00000037416|Vega:OTTMUSG00000042553 +240289 Gm4950 MGI:MGI:3649015 +240322 Adamts19 MGI:MGI:2442875|Ensembl:ENSMUSG00000053441 +240327 Gm4951 MGI:MGI:3644953|Ensembl:ENSMUSG00000073555|Vega:OTTMUSG00000033995 +240328 F830016B08Rik MGI:MGI:3588218|Ensembl:ENSMUSG00000090942 +240332 Slc6a7 MGI:MGI:2147363|Ensembl:ENSMUSG00000052026 +240334 Pcyox1l MGI:MGI:3606062|Ensembl:ENSMUSG00000024579|Vega:OTTMUSG00000028225 +240354 Malt1 MGI:MGI:2445027|Ensembl:ENSMUSG00000032688|Vega:OTTMUSG00000014910 +240396 Mex3c MGI:MGI:2652843|Ensembl:ENSMUSG00000037253|Vega:OTTMUSG00000034065 +240411 Loxhd1 MGI:MGI:1914609|Ensembl:ENSMUSG00000032818 +240427 Setbp1 MGI:MGI:1933199|Ensembl:ENSMUSG00000024548|Vega:OTTMUSG00000017269 +240442 Adnp2 MGI:MGI:2448562|Ensembl:ENSMUSG00000053950|Vega:OTTMUSG00000040169 +240444 Kcng2 MGI:MGI:3694646|Ensembl:ENSMUSG00000059852|Vega:OTTMUSG00000044919 +240476 Zfp407 MGI:MGI:2685179|Ensembl:ENSMUSG00000048410|Vega:OTTMUSG00000033200 +240479 Fam69c MGI:MGI:3041188|Ensembl:ENSMUSG00000047992|Vega:OTTMUSG00000028188 +240505 Cdc42bpg MGI:MGI:2652845|Ensembl:ENSMUSG00000024769|Vega:OTTMUSG00000018623 +240514 Ccdc85b MGI:MGI:2147607|Ensembl:ENSMUSG00000095098 +240518 Peli3 MGI:MGI:1924963|Ensembl:ENSMUSG00000024901|Vega:OTTMUSG00000029786 +240539 Gm336 MGI:MGI:2685182 +240549 Gm4952 MGI:MGI:3643569|Ensembl:ENSMUSG00000071633|Vega:OTTMUSG00000042671 +240590 Dmrt3 MGI:MGI:2449470|Ensembl:ENSMUSG00000042372 +240595 Kcnv2 MGI:MGI:2670981|Ensembl:ENSMUSG00000047298|Vega:OTTMUSG00000020413 +240613 9930021J03Rik MGI:MGI:2444398|Ensembl:ENSMUSG00000046138|Vega:OTTMUSG00000042117 +240614 Ranbp6 MGI:MGI:2683212|Ensembl:ENSMUSG00000074909|Vega:OTTMUSG00000054309 +240633 Lipk MGI:MGI:2679259|Ensembl:ENSMUSG00000024771 +240638 Slc16a12 MGI:MGI:2147716|Ensembl:ENSMUSG00000009378|Vega:OTTMUSG00000028405 +240641 Kif20b MGI:MGI:2444576|Ensembl:ENSMUSG00000024795 +240660 Slc35g1 MGI:MGI:2444789|Ensembl:ENSMUSG00000044026 +240665 Ccnj MGI:MGI:2443297|Ensembl:ENSMUSG00000025010|Vega:OTTMUSG00000028392 +240667 Sec31b MGI:MGI:2685187|Ensembl:ENSMUSG00000051984|Vega:OTTMUSG00000036224 +240669 Calhm3 MGI:MGI:3645665 +240672 Dusp5 MGI:MGI:2685183|Ensembl:ENSMUSG00000034765|Vega:OTTMUSG00000029765 +240675 Vwa2 MGI:MGI:2684334|Ensembl:ENSMUSG00000025082|Vega:OTTMUSG00000028252 +240690 St18 MGI:MGI:2446700|Ensembl:ENSMUSG00000033740|Vega:OTTMUSG00000024833 +240697 Mcmdc2 MGI:MGI:3045334|Ensembl:ENSMUSG00000046101|Vega:OTTMUSG00000021854 +240725 Sulf1 MGI:MGI:2138563|Ensembl:ENSMUSG00000016918|Vega:OTTMUSG00000047995 +240726 Slco5a1 MGI:MGI:2443431|Ensembl:ENSMUSG00000025938|Vega:OTTMUSG00000022327 +240752 Pik3c2b MGI:MGI:2685045|Ensembl:ENSMUSG00000026447|Vega:OTTMUSG00000021915 +240753 Plekha6 MGI:MGI:2388662|Ensembl:ENSMUSG00000041757|Vega:OTTMUSG00000049641 +240754 Lax1 MGI:MGI:2443362|Ensembl:ENSMUSG00000051998|Vega:OTTMUSG00000049667 +240755 4933406M09Rik MGI:MGI:3045320|Ensembl:ENSMUSG00000050526|Vega:OTTMUSG00000029248 +240756 Klhl12 MGI:MGI:2385619|Ensembl:ENSMUSG00000026455|Vega:OTTMUSG00000021463 +240776 Kcnt2 MGI:MGI:3036273|Ensembl:ENSMUSG00000052726|Vega:OTTMUSG00000029830 +240816 Rgsl1 MGI:MGI:2685048|Ensembl:ENSMUSG00000042641|Vega:OTTMUSG00000021823 +240817 Teddm2 MGI:MGI:1923273|Ensembl:ENSMUSG00000045968|Vega:OTTMUSG00000033702 +240819 Teddm1a MGI:MGI:2668439|Ensembl:ENSMUSG00000047053|Vega:OTTMUSG00000049774 +240832 Tor1aip2 MGI:MGI:3582695|Ensembl:ENSMUSG00000050565|Vega:OTTMUSG00000021976 +240843 Brinp2 MGI:MGI:2443333|Ensembl:ENSMUSG00000004031|Vega:OTTMUSG00000049880 +240853 Gm4953 MGI:MGI:3647627 +240869 Zbtb37 MGI:MGI:2444467|Ensembl:ENSMUSG00000043467|Vega:OTTMUSG00000021887 +240873 Tnfsf18 MGI:MGI:2673064|Ensembl:ENSMUSG00000066755|Vega:OTTMUSG00000026871 +240879 Mettl11b MGI:MGI:2685053|Ensembl:ENSMUSG00000040113|Vega:OTTMUSG00000034802 +240880 Scyl3 MGI:MGI:1921385|Ensembl:ENSMUSG00000026584|Vega:OTTMUSG00000034804 +240888 Gpr161 MGI:MGI:2685054|Ensembl:ENSMUSG00000040836|Vega:OTTMUSG00000049888 +240892 Dusp27 MGI:MGI:2685055|Ensembl:ENSMUSG00000026564|Vega:OTTMUSG00000050554 +240894 Fmo9 MGI:MGI:3606068|Ensembl:ENSMUSG00000026560|Vega:OTTMUSG00000022566 +240895 Gm4954 MGI:MGI:3648917 +240899 Lrrc52 MGI:MGI:1924118|Ensembl:ENSMUSG00000040485|Vega:OTTMUSG00000050637 +240913 Adamts4 MGI:MGI:1339949|Ensembl:ENSMUSG00000006403|Vega:OTTMUSG00000021528 +240916 Vsig8 MGI:MGI:3642995|Ensembl:ENSMUSG00000049598|Vega:OTTMUSG00000036736 +240921 Gm4955 MGI:MGI:3646410 +240960 Dnah14 MGI:MGI:2444525|Ensembl:ENSMUSG00000047369|Vega:OTTMUSG00000034874 +241035 Pkhd1 MGI:MGI:2155808|Ensembl:ENSMUSG00000043760|Vega:OTTMUSG00000026248 +241041 Gm4956 MGI:MGI:3647976|Ensembl:ENSMUSG00000025936 +241051 AA619741 MGI:MGI:3035322 +241052 C230030N03Rik MGI:MGI:3045297 +241053 Rpl12-ps1 MGI:MGI:3646154 +241062 Pgap1 MGI:MGI:2443342|Ensembl:ENSMUSG00000073678|Vega:OTTMUSG00000046957 +241066 Carf MGI:MGI:2182269|Ensembl:ENSMUSG00000026017|Vega:OTTMUSG00000022350 +241070 Gpr1 MGI:MGI:2385324|Ensembl:ENSMUSG00000046856|Vega:OTTMUSG00000002612 +241073 Dytn MGI:MGI:2685061|Ensembl:ENSMUSG00000069085|Vega:OTTMUSG00000008268 +241074 Gm13750 MGI:MGI:3650598 +241075 Plekhm3 MGI:MGI:2443627|Ensembl:ENSMUSG00000051344|Vega:OTTMUSG00000021993 +241084 Pced1c-ps MGI:MGI:3644590 +241112 Catip MGI:MGI:2685062|Ensembl:ENSMUSG00000073650|Vega:OTTMUSG00000026692 +241113 Prkag3 MGI:MGI:1891343|Ensembl:ENSMUSG00000006542|Vega:OTTMUSG00000034607 +241116 Cfap65 MGI:MGI:2444274|Ensembl:ENSMUSG00000047021|Vega:OTTMUSG00000026700 +241118 Asic4 MGI:MGI:2652846|Ensembl:ENSMUSG00000033007|Vega:OTTMUSG00000019418 +241128 Fam124b MGI:MGI:3026880|Ensembl:ENSMUSG00000043230|Vega:OTTMUSG00000034807 +241134 Nyap2 MGI:MGI:2443135|Ensembl:ENSMUSG00000054976|Vega:OTTMUSG00000026706 +241139 LOC241139 - +241158 Ankmy1 MGI:MGI:3045261|Ensembl:ENSMUSG00000034212|Vega:OTTMUSG00000021772 +241159 Neu4 MGI:MGI:2661364|Ensembl:ENSMUSG00000034000|Vega:OTTMUSG00000048695 +241175 Cntnap5b MGI:MGI:3664583|Ensembl:ENSMUSG00000067028|Vega:OTTMUSG00000048875 +241196 Serpinb13 MGI:MGI:3042250|Ensembl:ENSMUSG00000048775|Vega:OTTMUSG00000020999 +241197 Serpinb10 MGI:MGI:2138648|Ensembl:ENSMUSG00000092572|Vega:OTTMUSG00000020993 +241201 Cdh7 MGI:MGI:2442792|Ensembl:ENSMUSG00000026312|Vega:OTTMUSG00000022413 +241226 Itga8 MGI:MGI:109442|Ensembl:ENSMUSG00000026768|Vega:OTTMUSG00000011364 +241230 St8sia6 MGI:MGI:2386797|Ensembl:ENSMUSG00000003418|Vega:OTTMUSG00000011299 +241263 Gpr158 MGI:MGI:2441697|Ensembl:ENSMUSG00000045967|Vega:OTTMUSG00000011438 +241274 Pnpla7 MGI:MGI:2385325|Ensembl:ENSMUSG00000036833|Vega:OTTMUSG00000011617 +241275 Noxa1 MGI:MGI:2449980|Ensembl:ENSMUSG00000036805|Vega:OTTMUSG00000011780 +241289 Ppp1r26 MGI:MGI:2685193|Ensembl:ENSMUSG00000035829|Vega:OTTMUSG00000011648 +241296 Lrrc8a MGI:MGI:2652847|Ensembl:ENSMUSG00000007476|Ensembl:ENSMUSG00000099041|Vega:OTTMUSG00000016752|Vega:OTTMUSG00000044983 +241303 Fam78a MGI:MGI:2443569|Ensembl:ENSMUSG00000050592|Vega:OTTMUSG00000012944 +241308 Ralgps1 MGI:MGI:1922008|Ensembl:ENSMUSG00000038831|Vega:OTTMUSG00000012576 +241311 Zbtb34 MGI:MGI:2685195|Ensembl:ENSMUSG00000068966|Vega:OTTMUSG00000012578 +241322 Zbtb6 MGI:MGI:2442998|Ensembl:ENSMUSG00000066798|Vega:OTTMUSG00000012652 +241324 Crb2 MGI:MGI:2679260|Ensembl:ENSMUSG00000035403|Vega:OTTMUSG00000012713 +241327 Olfml2a MGI:MGI:2444741|Ensembl:ENSMUSG00000046618|Vega:OTTMUSG00000012165 +241391 Galnt5 MGI:MGI:2179403|Ensembl:ENSMUSG00000026828|Vega:OTTMUSG00000012598 +241431 Xirp2 MGI:MGI:2685198|Ensembl:ENSMUSG00000027022|Vega:OTTMUSG00000012905 +241447 Cers6 MGI:MGI:2442564|Ensembl:ENSMUSG00000027035|Vega:OTTMUSG00000012972 +241452 Dhrs9 MGI:MGI:2442798|Ensembl:ENSMUSG00000027068|Vega:OTTMUSG00000012989 +241489 Pde11a MGI:MGI:3036251|Ensembl:ENSMUSG00000075270|Vega:OTTMUSG00000015170 +241490 Rbm45 MGI:MGI:2387367|Ensembl:ENSMUSG00000042369|Vega:OTTMUSG00000013132 +241494 Zfp385b MGI:MGI:2444734|Ensembl:ENSMUSG00000027016|Vega:OTTMUSG00000015153 +241514 Zfp804a MGI:MGI:2442949|Ensembl:ENSMUSG00000070866|Vega:OTTMUSG00000013330 +241516 Fsip2 MGI:MGI:2664111|Ensembl:ENSMUSG00000075249|Vega:OTTMUSG00000013335 +241520 Fam171b MGI:MGI:2444579|Ensembl:ENSMUSG00000048388|Vega:OTTMUSG00000013394 +241525 Ypel4 MGI:MGI:3605071|Ensembl:ENSMUSG00000034059|Vega:OTTMUSG00000013681 +241528 Lrrc55 MGI:MGI:2685197|Ensembl:ENSMUSG00000075224 +241547 Harbi1 MGI:MGI:2443194|Ensembl:ENSMUSG00000027243|Vega:OTTMUSG00000014309 +241556 Tspan18 MGI:MGI:1917186|Ensembl:ENSMUSG00000027217|Vega:OTTMUSG00000014540 +241568 Lrrc4c MGI:MGI:2442636|Ensembl:ENSMUSG00000050587|Vega:OTTMUSG00000014522 +241572 Gm13812 MGI:MGI:3649741 +241576 Ldlrad3 MGI:MGI:2138856|Ensembl:ENSMUSG00000048058|Vega:OTTMUSG00000019155 +241589 D430041D05Rik MGI:MGI:2181743|Ensembl:ENSMUSG00000068373 +241593 Pin1rt1 MGI:MGI:3649546|Ensembl:ENSMUSG00000074997|Vega:OTTMUSG00000014964 +241612 Slc5a12 MGI:MGI:2138890|Ensembl:ENSMUSG00000041644|Vega:OTTMUSG00000015135 +241621 Gm13981 MGI:MGI:3652167 +241624 Exd1 MGI:MGI:3045306|Ensembl:ENSMUSG00000048647|Vega:OTTMUSG00000015952 +241627 Wdr76 MGI:MGI:1926186|Ensembl:ENSMUSG00000027242|Vega:OTTMUSG00000015376 +241633 Atp8b4 MGI:MGI:1859664|Ensembl:ENSMUSG00000060131|Vega:OTTMUSG00000015754 +241634 Spdye4c MGI:MGI:2685201|Ensembl:ENSMUSG00000074812|Vega:OTTMUSG00000015362 +241636 Tgm6 MGI:MGI:3044321|Ensembl:ENSMUSG00000027403|Vega:OTTMUSG00000015503 +241638 Lzts3 MGI:MGI:2656976|Ensembl:ENSMUSG00000037703|Vega:OTTMUSG00000015518 +241639 Fermt1 MGI:MGI:2443583|Ensembl:ENSMUSG00000027356|Vega:OTTMUSG00000015663 +241656 Pak7 MGI:MGI:1920334|Ensembl:ENSMUSG00000039913|Vega:OTTMUSG00000015988 +241688 Dzank1 MGI:MGI:2139080|Ensembl:ENSMUSG00000037259|Vega:OTTMUSG00000004235 +241694 Ralgapa2 MGI:MGI:3036245|Ensembl:ENSMUSG00000037110|Vega:OTTMUSG00000015703 +241715 Gm14131 MGI:MGI:3652215 +241727 Snph MGI:MGI:2139270|Ensembl:ENSMUSG00000027457|Vega:OTTMUSG00000014818 +241732 Tspyl3 MGI:MGI:2139328|Ensembl:ENSMUSG00000074671|Vega:OTTMUSG00000016733 +241764 L3mbtl1 MGI:MGI:2676663|Ensembl:ENSMUSG00000035576|Vega:OTTMUSG00000001061 +241765 Gm11453 MGI:MGI:3650734 +241769 Kcnk15 MGI:MGI:2675209|Ensembl:ENSMUSG00000035238|Vega:OTTMUSG00000001074 +241770 Rims4 MGI:MGI:2674366|Ensembl:ENSMUSG00000035226|Vega:OTTMUSG00000001075 +241794 Kcng1 MGI:MGI:3616086|Ensembl:ENSMUSG00000074575|Vega:OTTMUSG00000016048 +241846 Lsm14b MGI:MGI:3040677|Ensembl:ENSMUSG00000039108|Vega:OTTMUSG00000016234 +241850 Abhd16b MGI:MGI:3607711|Ensembl:ENSMUSG00000055882|Vega:OTTMUSG00000016708 +241877 Slc10a5 MGI:MGI:2685251|Ensembl:ENSMUSG00000058921|Vega:OTTMUSG00000051492 +241915 Phc3 MGI:MGI:2181434|Ensembl:ENSMUSG00000037652|Vega:OTTMUSG00000023470 +241919 Slc7a14 MGI:MGI:3040688|Ensembl:ENSMUSG00000069072|Vega:OTTMUSG00000022774 +241943 Ccdc144b MGI:MGI:2681852|Ensembl:ENSMUSG00000047696|Vega:OTTMUSG00000029230 +241944 D3Ertd254e MGI:MGI:1098769|Ensembl:ENSMUSG00000033883|Vega:OTTMUSG00000052214 +241950 Bbs12 MGI:MGI:2686651|Ensembl:ENSMUSG00000051444|Vega:OTTMUSG00000007355 +241989 Pabpc4l MGI:MGI:3643087|Ensembl:ENSMUSG00000090919|Vega:OTTMUSG00000051437 +242022 Frem2 MGI:MGI:2444465|Ensembl:ENSMUSG00000037016|Vega:OTTMUSG00000053495 +242037 Ankub1 MGI:MGI:2685256|Ensembl:ENSMUSG00000074591|Vega:OTTMUSG00000021989 +242050 Igsf10 MGI:MGI:1923481|Ensembl:ENSMUSG00000036334|Vega:OTTMUSG00000052181 +242083 Ppm1l MGI:MGI:2139740|Ensembl:ENSMUSG00000027784|Vega:OTTMUSG00000026599 +242093 Rxfp4 MGI:MGI:2182926|Ensembl:ENSMUSG00000049741|Vega:OTTMUSG00000044335 +242100 Pglyrp3 MGI:MGI:2685266|Ensembl:ENSMUSG00000042244|Vega:OTTMUSG00000026663 +242109 Zfp697 MGI:MGI:2139736|Ensembl:ENSMUSG00000050064|Vega:OTTMUSG00000054013 +242122 Vtcn1 MGI:MGI:3039619|Ensembl:ENSMUSG00000051076|Vega:OTTMUSG00000007078 +242125 Mab21l3 MGI:MGI:2446273|Ensembl:ENSMUSG00000044313|Vega:OTTMUSG00000026626 +242126 Slc22a15 MGI:MGI:3607704|Ensembl:ENSMUSG00000033147|Vega:OTTMUSG00000044355 +242151 Kcna10 MGI:MGI:3037820|Ensembl:ENSMUSG00000042861|Vega:OTTMUSG00000035283 +242161 LOC242161 - +242202 Pde5a MGI:MGI:2651499|Ensembl:ENSMUSG00000053965|Vega:OTTMUSG00000052456 +242235 Lrit3 MGI:MGI:2685267|Ensembl:ENSMUSG00000093865|Vega:OTTMUSG00000045099 +242248 Bank1 MGI:MGI:2442120|Ensembl:ENSMUSG00000037922|Vega:OTTMUSG00000052558 +242253 Wdr63 MGI:MGI:3045269|Ensembl:ENSMUSG00000043020|Vega:OTTMUSG00000034287 +242259 Slc44a5 MGI:MGI:3035141|Ensembl:ENSMUSG00000028360|Vega:OTTMUSG00000030388 +242274 Lrrc7 MGI:MGI:2676665|Ensembl:ENSMUSG00000028176|Vega:OTTMUSG00000052788 +242285 Sdr16c5 MGI:MGI:2668443|Ensembl:ENSMUSG00000028236|Vega:OTTMUSG00000004400 +242286 Sdr16c6 MGI:MGI:2685269|Ensembl:ENSMUSG00000071019|Vega:OTTMUSG00000004399 +242291 Impad1 MGI:MGI:1915720|Ensembl:ENSMUSG00000066324|Vega:OTTMUSG00000004196 +242297 Fam110b MGI:MGI:1916593|Ensembl:ENSMUSG00000049119|Vega:OTTMUSG00000004221 +242316 Gdf6 MGI:MGI:95689|Ensembl:ENSMUSG00000051279|Vega:OTTMUSG00000004534 +242341 Atp6v0d2 MGI:MGI:1924415|Ensembl:ENSMUSG00000028238|Vega:OTTMUSG00000006382 +242362 Manea MGI:MGI:2444484|Ensembl:ENSMUSG00000040520|Vega:OTTMUSG00000004825 +242377 Pm20d2 MGI:MGI:2685270|Ensembl:ENSMUSG00000054659|Vega:OTTMUSG00000004919 +242384 Lingo2 MGI:MGI:2442298|Ensembl:ENSMUSG00000045083|Vega:OTTMUSG00000006502 +242406 Rgp1 MGI:MGI:1915956|Ensembl:ENSMUSG00000028468|Vega:OTTMUSG00000007016 +242408 Fam221b MGI:MGI:2441678|Ensembl:ENSMUSG00000043633|Vega:OTTMUSG00000007048 +242409 Tmem8b MGI:MGI:2441680|Ensembl:ENSMUSG00000078716|Vega:OTTMUSG00000007050 +242418 Dcaf10 MGI:MGI:2140179|Ensembl:ENSMUSG00000035572|Vega:OTTMUSG00000007621 +242425 Gabbr2 MGI:MGI:2386030|Ensembl:ENSMUSG00000039809|Vega:OTTMUSG00000006774 +242443 Grin3a MGI:MGI:1933206|Ensembl:ENSMUSG00000039579|Vega:OTTMUSG00000006949 +242466 Zfp462 MGI:MGI:107690|Ensembl:ENSMUSG00000060206|Vega:OTTMUSG00000007225 +242474 Tmem245 MGI:MGI:2445107|Ensembl:ENSMUSG00000055296|Vega:OTTMUSG00000007316 +242481 Palm2 MGI:MGI:1934601|Ensembl:ENSMUSG00000090053|Vega:OTTMUSG00000007323 +242484 D630039A03Rik MGI:MGI:2442889|Ensembl:ENSMUSG00000052117|Vega:OTTMUSG00000007369 +242497 Gm11224 MGI:MGI:3651640 +242502 Gm428 MGI:MGI:2685274|Ensembl:ENSMUSG00000095341|Vega:OTTMUSG00000000284 +242505 Rasef MGI:MGI:2448565|Ensembl:ENSMUSG00000043003|Vega:OTTMUSG00000000285 +242506 Frmd3 MGI:MGI:2442466|Ensembl:ENSMUSG00000049122|Vega:OTTMUSG00000000793 +242509 Bnc2 MGI:MGI:2443805|Ensembl:ENSMUSG00000028487|Vega:OTTMUSG00000006757 +242517 Ifna15 MGI:MGI:3649418|Ensembl:ENSMUSG00000096011|Vega:OTTMUSG00000007655 +242519 Ifna12 MGI:MGI:2676324|Ensembl:ENSMUSG00000073811|Vega:OTTMUSG00000007663 +242521 Klhl9 MGI:MGI:2180122|Ensembl:ENSMUSG00000070923|Vega:OTTMUSG00000011283 +242523 Dmrta1 MGI:MGI:2653627|Ensembl:ENSMUSG00000043753|Vega:OTTMUSG00000007714 +242546 Cyp2j12 MGI:MGI:3717097|Ensembl:ENSMUSG00000081225|Vega:OTTMUSG00000007939 +242553 Kank4 MGI:MGI:3043381|Ensembl:ENSMUSG00000035407|Vega:OTTMUSG00000008669 +242557 Atg4c MGI:MGI:2651854|Ensembl:ENSMUSG00000028550|Vega:OTTMUSG00000007980 +242570 Raver2 MGI:MGI:2443623|Ensembl:ENSMUSG00000035275|Vega:OTTMUSG00000008206 +242574 C130073F10Rik MGI:MGI:3045359|Ensembl:ENSMUSG00000046133|Vega:OTTMUSG00000008461 +242584 Wdr78 MGI:MGI:2385328|Ensembl:ENSMUSG00000035126|Vega:OTTMUSG00000008069 +242585 Slc35d1 MGI:MGI:2140361|Ensembl:ENSMUSG00000028521|Vega:OTTMUSG00000008067 +242594 Fyb2 MGI:MGI:2685466|Ensembl:ENSMUSG00000078612|Vega:OTTMUSG00000008126 +242602 Lexm MGI:MGI:2681853|Ensembl:ENSMUSG00000054362|Vega:OTTMUSG00000008156 +242603 Cdcp2 MGI:MGI:3045328|Ensembl:ENSMUSG00000047636|Vega:OTTMUSG00000008474 +242607 Slc1a7 MGI:MGI:2444087|Ensembl:ENSMUSG00000008932|Vega:OTTMUSG00000009321 +242608 Podn MGI:MGI:2674939|Ensembl:ENSMUSG00000028600|Vega:OTTMUSG00000009385 +242620 Dmrta2 MGI:MGI:2653629|Ensembl:ENSMUSG00000047143|Vega:OTTMUSG00000008499 +242627 Skint5 MGI:MGI:3650151|Ensembl:ENSMUSG00000078598|Vega:OTTMUSG00000008560 +242642 Hpdl MGI:MGI:2444646|Ensembl:ENSMUSG00000043155|Vega:OTTMUSG00000009753 +242646 Tctex1d4 MGI:MGI:3045358|Ensembl:ENSMUSG00000047671|Vega:OTTMUSG00000009918 +242653 Cldn19 MGI:MGI:3033992|Ensembl:ENSMUSG00000066058|Vega:OTTMUSG00000009224 +242662 Rims3 MGI:MGI:2443331|Ensembl:ENSMUSG00000032890|Vega:OTTMUSG00000008857 +242667 Dlgap3 MGI:MGI:3039563|Ensembl:ENSMUSG00000042388|Vega:OTTMUSG00000009331 +242669 Azin2 MGI:MGI:2442093|Ensembl:ENSMUSG00000028789|Vega:OTTMUSG00000009540 +242681 Rab42 MGI:MGI:2441753|Ensembl:ENSMUSG00000089687|Vega:OTTMUSG00000011109 +242687 Wasf2 MGI:MGI:1098641|Ensembl:ENSMUSG00000028868|Vega:OTTMUSG00000010477 +242691 Gpatch3 MGI:MGI:2442492|Ensembl:ENSMUSG00000028850|Vega:OTTMUSG00000011159 +242700 Ifnlr1 MGI:MGI:2429859|Ensembl:ENSMUSG00000062157|Vega:OTTMUSG00000009736 +242702 Myom3 MGI:MGI:2685280|Ensembl:ENSMUSG00000037139|Vega:OTTMUSG00000009726 +242705 E2f2 MGI:MGI:1096341|Ensembl:ENSMUSG00000018983|Vega:OTTMUSG00000009869 +242707 Lactbl1 MGI:MGI:2448566|Ensembl:ENSMUSG00000070683|Vega:OTTMUSG00000009703 +242711 Cela3a MGI:MGI:3651647|Ensembl:ENSMUSG00000078520|Vega:OTTMUSG00000009877 +242721 Klhdc7a MGI:MGI:2444612|Ensembl:ENSMUSG00000078234|Vega:OTTMUSG00000010055 +242726 Padi6 MGI:MGI:2655198|Ensembl:ENSMUSG00000040935|Vega:OTTMUSG00000010035 +242735 Lrrc38 MGI:MGI:2442845|Ensembl:ENSMUSG00000028584|Vega:OTTMUSG00000010227 +242736 Pramef8 MGI:MGI:2140473|Ensembl:ENSMUSG00000046862|Vega:OTTMUSG00000010133 +242737 Oog4 MGI:MGI:2684051|Ensembl:ENSMUSG00000047799|Vega:OTTMUSG00000010135 +242747 Zfp933 MGI:MGI:1922865|Ensembl:ENSMUSG00000059423|Vega:OTTMUSG00000010676 +242748 Disp3 MGI:MGI:2444403|Ensembl:ENSMUSG00000041544|Vega:OTTMUSG00000010955 +242773 Slc45a1 MGI:MGI:2653235|Ensembl:ENSMUSG00000039838|Vega:OTTMUSG00000010395 +242785 Klhl21 MGI:MGI:1919288|Ensembl:ENSMUSG00000073700|Vega:OTTMUSG00000010376 +242800 Ttc34 MGI:MGI:2445205|Ensembl:ENSMUSG00000046637|Vega:OTTMUSG00000010463 +242805 Ankrd65 MGI:MGI:2685285|Ensembl:ENSMUSG00000078487 +242809 Gm4959 MGI:MGI:3647044 +242819 Rundc3b MGI:MGI:2685286|Ensembl:ENSMUSG00000040570|Vega:OTTMUSG00000023112 +242823 Gm4960 MGI:MGI:3647275 +242838 Lrrd1 MGI:MGI:3045299|Ensembl:ENSMUSG00000040367|Vega:OTTMUSG00000026683 +242851 Gnat3 MGI:MGI:3588268|Ensembl:ENSMUSG00000028777|Vega:OTTMUSG00000053053 +242860 Rsbn1l MGI:MGI:3036237|Ensembl:ENSMUSG00000039968 +242864 Napepld MGI:MGI:2140885|Ensembl:ENSMUSG00000044968|Vega:OTTMUSG00000025672 +242891 Cct8l1 MGI:MGI:2685289|Ensembl:ENSMUSG00000038044|Vega:OTTMUSG00000053841 +242894 Actr3b MGI:MGI:2661120|Ensembl:ENSMUSG00000056367|Vega:OTTMUSG00000026695 +242914 Gm4961 MGI:MGI:3645260|Ensembl:ENSMUSG00000104667 +242915 Garem2 MGI:MGI:2685290|Ensembl:ENSMUSG00000044576|Vega:OTTMUSG00000024745 +242939 Cpz MGI:MGI:88487|Ensembl:ENSMUSG00000036596|Vega:OTTMUSG00000024316 +242960 Fbxl5 MGI:MGI:2152883|Ensembl:ENSMUSG00000039753|Vega:OTTMUSG00000053749 +242987 Gm4962 MGI:MGI:3643111 +243025 Tmem156 MGI:MGI:2685292|Ensembl:ENSMUSG00000037913|Vega:OTTMUSG00000044566 +243043 Kctd8 MGI:MGI:2443804|Ensembl:ENSMUSG00000037653|Vega:OTTMUSG00000028715 +243078 Tecrl MGI:MGI:2444966|Ensembl:ENSMUSG00000049537|Vega:OTTMUSG00000024555 +243083 Tmprss11f MGI:MGI:2442348|Ensembl:ENSMUSG00000048764|Vega:OTTMUSG00000035103 +243084 Tmprss11e MGI:MGI:3513175|Ensembl:ENSMUSG00000054537|Vega:OTTMUSG00000035105 +243085 Ugt2b35 MGI:MGI:3576100|Ensembl:ENSMUSG00000035811|Vega:OTTMUSG00000030267 +243090 BC051076 MGI:MGI:2670982 +243168 Hsd17b13 MGI:MGI:2140804|Ensembl:ENSMUSG00000034528|Vega:OTTMUSG00000026811 +243197 Mfsd7a MGI:MGI:2442629|Ensembl:ENSMUSG00000029490 +243219 2900026A02Rik MGI:MGI:1920194|Ensembl:ENSMUSG00000051339|Vega:OTTMUSG00000025834 +243262 Oas1f MGI:MGI:2180855|Ensembl:ENSMUSG00000053765|Vega:OTTMUSG00000025363 +243270 Hcar1 MGI:MGI:2441671|Ensembl:ENSMUSG00000049241|Vega:OTTMUSG00000037966 +243272 Sbno1 MGI:MGI:2384298|Ensembl:ENSMUSG00000038095|Vega:OTTMUSG00000054850 +243274 Tmem132d MGI:MGI:3044963|Ensembl:ENSMUSG00000034310|Vega:OTTMUSG00000036807 +243277 Adgrd1 MGI:MGI:3041203|Ensembl:ENSMUSG00000044017|Vega:OTTMUSG00000027719 +243300 Nyap1 MGI:MGI:2443880|Ensembl:ENSMUSG00000045348|Vega:OTTMUSG00000026838 +243302 Gm4963 MGI:MGI:3645168 +243303 Gm454 MGI:MGI:2685300 +243308 A430033K04Rik MGI:MGI:3583896|Ensembl:ENSMUSG00000056014|Vega:OTTMUSG00000054717 +243312 Elfn1 MGI:MGI:2442479|Ensembl:ENSMUSG00000048988|Vega:OTTMUSG00000054804 +243328 Slc29a4 MGI:MGI:2385330|Ensembl:ENSMUSG00000050822|Vega:OTTMUSG00000054882 +243339 Tmem130 MGI:MGI:3607706|Ensembl:ENSMUSG00000043388|Vega:OTTMUSG00000025590 +243362 Stard13 MGI:MGI:2385331|Ensembl:ENSMUSG00000016128|Vega:OTTMUSG00000023438 +243369 Sspo MGI:MGI:2674311|Ensembl:ENSMUSG00000029797|Vega:OTTMUSG00000045396 +243371 Lrrc61 MGI:MGI:2652848|Ensembl:ENSMUSG00000073096|Vega:OTTMUSG00000024299 +243372 Zfp775 MGI:MGI:2683557|Ensembl:ENSMUSG00000007216|Vega:OTTMUSG00000057234 +243373 AI854703 MGI:MGI:2141510|Ensembl:ENSMUSG00000053297|Vega:OTTMUSG00000033717 +243374 Gimap8 MGI:MGI:2685303|Ensembl:ENSMUSG00000064262|Vega:OTTMUSG00000057237 +243376 Doxl2 MGI:MGI:3618290|Ensembl:ENSMUSG00000068536|Vega:OTTMUSG00000044589 +243377 Svs1 MGI:MGI:2682321|Ensembl:ENSMUSG00000039215|Vega:OTTMUSG00000057399 +243382 Ppm1k MGI:MGI:2442111|Ensembl:ENSMUSG00000037826|Vega:OTTMUSG00000039933 +243385 Gprin3 MGI:MGI:1924785|Ensembl:ENSMUSG00000045441|Vega:OTTMUSG00000057687 +243407 C130060K24Rik MGI:MGI:2441881|Ensembl:ENSMUSG00000029917|Vega:OTTMUSG00000022949 +243420 Igkv1-135 MGI:MGI:3819952|IMGT/GENE-DB:IGKV1-135 +243423 Igkv1-132 MGI:MGI:3648800|IMGT/GENE-DB:IGKV1-132 +243428 Igkv11-125 MGI:MGI:3642338|IMGT/GENE-DB:IGKV11-125 +243431 Igkv9-124 MGI:MGI:3646892|IMGT/GENE-DB:IGKV9-124 +243433 Igkv17-127 MGI:MGI:3646891|IMGT/GENE-DB:IGKV17-127 +243439 Igkv14-100 MGI:MGI:4439559|IMGT/GENE-DB:IGKV14-100 +243451 Igkv4-86 MGI:MGI:2685305|IMGT/GENE-DB:IGKV4-86 +243453 Igkv4-81 MGI:MGI:2685306|IMGT/GENE-DB:IGKV4-81 +243461 Igkv7-33 MGI:MGI:3577282|IMGT/GENE-DB:IGKV7-33 +243469 Igk MGI:MGI:96494 +243499 Lrrtm4 MGI:MGI:2389180|Ensembl:ENSMUSG00000052581|Vega:OTTMUSG00000034091 +243510 Ccdc142 MGI:MGI:3045292|Ensembl:ENSMUSG00000079511|Ensembl:ENSMUSG00000107499|Vega:OTTMUSG00000024263|Vega:OTTMUSG00000024264 +243529 H1fx MGI:MGI:2685307|Ensembl:ENSMUSG00000044927|Vega:OTTMUSG00000024647 +243535 BC048671 MGI:MGI:2679261|Ensembl:ENSMUSG00000049694|Vega:OTTMUSG00000037490 +243537 Uroc1 MGI:MGI:2385332|Ensembl:ENSMUSG00000034456|Vega:OTTMUSG00000036118 +243538 Cfap100 MGI:MGI:2141635|Ensembl:ENSMUSG00000048794|Vega:OTTMUSG00000029676 +243547 Grip2 MGI:MGI:2681173|Ensembl:ENSMUSG00000030098|Vega:OTTMUSG00000034562 +243548 Prickle2 MGI:MGI:1925144|Ensembl:ENSMUSG00000030020|Vega:OTTMUSG00000022502 +243574 Kbtbd8 MGI:MGI:2661430|Ensembl:ENSMUSG00000030031|Vega:OTTMUSG00000029697 +243612 Ssu2 MGI:MGI:2443733|Ensembl:ENSMUSG00000034387|Vega:OTTMUSG00000027023 +243616 Slc6a11 MGI:MGI:95630|Ensembl:ENSMUSG00000030307|Vega:OTTMUSG00000056547 +243621 Iqsec3 MGI:MGI:2677208|Ensembl:ENSMUSG00000040797|Vega:OTTMUSG00000023463 +243628 Vmn2r24 MGI:MGI:3647530|Ensembl:ENSMUSG00000072780|Vega:OTTMUSG00000040031 +243634 Ano2 MGI:MGI:2387214|Ensembl:ENSMUSG00000038115|Vega:OTTMUSG00000033377 +243642 Gm4968 MGI:MGI:3647516 +243653 Clec1a MGI:MGI:2444151|Ensembl:ENSMUSG00000033082|Vega:OTTMUSG00000056468 +243655 Klre1 MGI:MGI:2662547|Ensembl:ENSMUSG00000050241|Vega:OTTMUSG00000056473 +243659 Styk1 MGI:MGI:2141396|Ensembl:ENSMUSG00000032899|Vega:OTTMUSG00000027070 +243725 Ppp1r9a MGI:MGI:2442401|Ensembl:ENSMUSG00000032827|Vega:OTTMUSG00000042256 +243743 Plxna4 MGI:MGI:2179061|Ensembl:ENSMUSG00000029765|Vega:OTTMUSG00000014752 +243753 Slc23a4 MGI:MGI:1917272|Ensembl:ENSMUSG00000029847|Vega:OTTMUSG00000022784 +243755 Slc13a4 MGI:MGI:2442367|Ensembl:ENSMUSG00000029843|Vega:OTTMUSG00000022429 +243764 Chrm2 MGI:MGI:88397|Ensembl:ENSMUSG00000045613|Vega:OTTMUSG00000036825 +243771 Parp12 MGI:MGI:2143990|Ensembl:ENSMUSG00000038507|Vega:OTTMUSG00000023211 +243780 E330009J07Rik MGI:MGI:2444256|Ensembl:ENSMUSG00000037172|Vega:OTTMUSG00000022837 +243813 Leng9 MGI:MGI:2444509|Ensembl:ENSMUSG00000043432|Vega:OTTMUSG00000027899 +243816 Gp6 MGI:MGI:1889810|Ensembl:ENSMUSG00000078810|Vega:OTTMUSG00000058573 +243819 Ppp6r1 MGI:MGI:2442163|Ensembl:ENSMUSG00000052296|Vega:OTTMUSG00000058443 +243822 Fam71e2 MGI:MGI:3045311|Ensembl:ENSMUSG00000092518|Vega:OTTMUSG00000036799 +243833 Zfp128 MGI:MGI:2389445|Ensembl:ENSMUSG00000060397|Vega:OTTMUSG00000022356 +243834 Zfp324 MGI:MGI:2444641|Ensembl:ENSMUSG00000004500|Vega:OTTMUSG00000022360 +243842 Bicra MGI:MGI:2154263|Ensembl:ENSMUSG00000070808|Vega:OTTMUSG00000060702 +243846 Ccdc9 MGI:MGI:1921443|Ensembl:ENSMUSG00000041375|Vega:OTTMUSG00000029301 +243853 Fkrp MGI:MGI:2447586|Ensembl:ENSMUSG00000048920|Vega:OTTMUSG00000058117 +243862 Psg22 MGI:MGI:1891354|Ensembl:ENSMUSG00000044903|Vega:OTTMUSG00000017118 +243864 Mill2 MGI:MGI:2179989|Ensembl:ENSMUSG00000040987|Vega:OTTMUSG00000058434 +243866 Gm4969 MGI:MGI:3647482|Ensembl:ENSMUSG00000085601|Vega:OTTMUSG00000033786 +243867 Fbxo46 MGI:MGI:2444918|Ensembl:ENSMUSG00000050428|Vega:OTTMUSG00000058569 +243872 Rpl7a-ps8 MGI:MGI:3644288 +243874 Nlrp9b MGI:MGI:2675377|Ensembl:ENSMUSG00000060508|Vega:OTTMUSG00000027189 +243880 Nlrp4a MGI:MGI:2443697|Ensembl:ENSMUSG00000040601|Vega:OTTMUSG00000027159 +243881 Cyp2b23 MGI:MGI:3646735|Ensembl:ENSMUSG00000040650|Vega:OTTMUSG00000022527 +243897 Ggn MGI:MGI:2181461|Ensembl:ENSMUSG00000031493|Vega:OTTMUSG00000059214 +243900 4930432E11Rik MGI:MGI:3045259 +243905 Zfp568 MGI:MGI:2142347|Ensembl:ENSMUSG00000074221|Vega:OTTMUSG00000033725 +243906 Zfp14 MGI:MGI:99160|Ensembl:ENSMUSG00000053985|Vega:OTTMUSG00000059307 +243910 Nfkbid MGI:MGI:3041243|Ensembl:ENSMUSG00000036931|Vega:OTTMUSG00000026225 +243911 Kirrel2 MGI:MGI:2442334|Ensembl:ENSMUSG00000036915|Vega:OTTMUSG00000031127 +243912 Hspb6 MGI:MGI:2685325|Ensembl:ENSMUSG00000036854|Vega:OTTMUSG00000026204 +243914 Lgi4 MGI:MGI:2180197|Ensembl:ENSMUSG00000036560|Vega:OTTMUSG00000036043 +243923 Rgs9bp MGI:MGI:2384418|Ensembl:ENSMUSG00000056043|Vega:OTTMUSG00000049777 +243931 Tshz3 MGI:MGI:2442819|Ensembl:ENSMUSG00000021217|Vega:OTTMUSG00000040171 +243937 Zfp536 MGI:MGI:1926102|Ensembl:ENSMUSG00000043456|Vega:OTTMUSG00000042179 +243944 4930433I11Rik MGI:MGI:2685327|Ensembl:ENSMUSG00000091692|Vega:OTTMUSG00000048800 +243958 Siglecg MGI:MGI:2443630|Ensembl:ENSMUSG00000030468|Vega:OTTMUSG00000031927 +243961 Shank1 MGI:MGI:3613677|Ensembl:ENSMUSG00000038738|Vega:OTTMUSG00000016443 +243963 Zfp473 MGI:MGI:2442697|Ensembl:ENSMUSG00000048012|Vega:OTTMUSG00000029523 +243967 Ntn5 MGI:MGI:2685330|Ensembl:ENSMUSG00000070564|Vega:OTTMUSG00000043309 +243978 Mrgprx2 MGI:MGI:3588270|Ensembl:ENSMUSG00000074109|Vega:OTTMUSG00000046626 +243979 Mrgprb2 MGI:MGI:2441674|Ensembl:ENSMUSG00000050425|Vega:OTTMUSG00000046627 +243983 Zdhhc13 MGI:MGI:1919227|Ensembl:ENSMUSG00000030471|Vega:OTTMUSG00000030356 +243996 4933405O20Rik MGI:MGI:2142174|Ensembl:ENSMUSG00000084234|Vega:OTTMUSG00000024738 +244049 Mctp2 MGI:MGI:2685335|Ensembl:ENSMUSG00000032776|Vega:OTTMUSG00000049579 +244058 Rgma MGI:MGI:2679262|Ensembl:ENSMUSG00000070509|Vega:OTTMUSG00000031394 +244059 Chd2 MGI:MGI:2448567|Ensembl:ENSMUSG00000078671|Vega:OTTMUSG00000036993 +244061 Gm4971 MGI:MGI:3643321|Ensembl:ENSMUSG00000108337 +244071 Agbl1 MGI:MGI:3646469|Ensembl:ENSMUSG00000025754|Vega:OTTMUSG00000024913 +244091 Fsd2 MGI:MGI:2444310|Ensembl:ENSMUSG00000038663|Vega:OTTMUSG00000055593 +244114 Vmn2r72 MGI:MGI:3647591|Ensembl:ENSMUSG00000051877|Vega:OTTMUSG00000037820 +244141 Nars2 MGI:MGI:2142075|Ensembl:ENSMUSG00000018995|Vega:OTTMUSG00000024430 +244144 Usp35 MGI:MGI:2685339|Ensembl:ENSMUSG00000035713|Vega:OTTMUSG00000029537 +244152 Tsku MGI:MGI:2443855|Ensembl:ENSMUSG00000049580|Vega:OTTMUSG00000058850 +244178 Ubqln3 MGI:MGI:3045291|Ensembl:ENSMUSG00000051618|Vega:OTTMUSG00000019032 +244179 Ubqlnl MGI:MGI:2685336|Ensembl:ENSMUSG00000051437|Vega:OTTMUSG00000019082 +244180 Olfm5 MGI:MGI:2443346|Ensembl:ENSMUSG00000044265|Vega:OTTMUSG00000019016 +244183 Trim30b MGI:MGI:4821256|Ensembl:ENSMUSG00000052749 +244187 Olfr684 MGI:MGI:3030518|Ensembl:ENSMUSG00000047225|Vega:OTTMUSG00000060649 +244189 Gm4972 MGI:MGI:3643689 +244198 Olfml1 MGI:MGI:2679264|Ensembl:ENSMUSG00000051041|Vega:OTTMUSG00000029940 +244199 Ovch2 MGI:MGI:3045251|Ensembl:ENSMUSG00000048236|Vega:OTTMUSG00000023453 +244202 Nlrp10 MGI:MGI:2444084|Ensembl:ENSMUSG00000049709|Vega:OTTMUSG00000060096 +244209 Cyp2r1 MGI:MGI:2449771|Ensembl:ENSMUSG00000030670|Vega:OTTMUSG00000027373 +244214 Gm4973 MGI:MGI:3643455 +244216 Zfp771 MGI:MGI:2442050|Ensembl:ENSMUSG00000054716|Vega:OTTMUSG00000022480 +244218 Ctf2 MGI:MGI:2684607|Ensembl:ENSMUSG00000060034|Vega:OTTMUSG00000030582 +244219 Zfp668 MGI:MGI:2442943|Ensembl:ENSMUSG00000049728|Vega:OTTMUSG00000022499 +244229 Gm4974 MGI:MGI:3646627 +244233 Cd163l1 MGI:MGI:2443796|Ensembl:ENSMUSG00000025461|Vega:OTTMUSG00000060577 +244234 5830411N06Rik MGI:MGI:2443685|Ensembl:ENSMUSG00000054672|Vega:OTTMUSG00000060578 +244237 Tnfrsf26 MGI:MGI:2651928|Ensembl:ENSMUSG00000045362|Vega:OTTMUSG00000060030 +244238 Mrgpre MGI:MGI:2441884|Ensembl:ENSMUSG00000048965|Vega:OTTMUSG00000060034 +244239 Gm498 MGI:MGI:2685344 +244281 Myo16 MGI:MGI:2685951|Ensembl:ENSMUSG00000039057|Vega:OTTMUSG00000059084 +244310 Dlgap2 MGI:MGI:2443181|Ensembl:ENSMUSG00000047495|Vega:OTTMUSG00000034008 +244329 Mcph1 MGI:MGI:2443308|Ensembl:ENSMUSG00000039842|Vega:OTTMUSG00000020492 +244332 Defb14 MGI:MGI:2675345|Ensembl:ENSMUSG00000046354|Vega:OTTMUSG00000020600 +244334 Defb8 MGI:MGI:2654206|Ensembl:ENSMUSG00000031471|Vega:OTTMUSG00000020716 +244349 Kat6a MGI:MGI:2442415|Ensembl:ENSMUSG00000031540|Vega:OTTMUSG00000017302 +244373 Erlin2 MGI:MGI:2387215|Ensembl:ENSMUSG00000031483|Vega:OTTMUSG00000060978 +244416 Ppp1r3b MGI:MGI:2177268|Ensembl:ENSMUSG00000046794|Vega:OTTMUSG00000061024 +244418 Prag1 MGI:MGI:1196223|Ensembl:ENSMUSG00000050271|Vega:OTTMUSG00000022666 +244421 Lonrf1 MGI:MGI:3609241|Ensembl:ENSMUSG00000039633|Vega:OTTMUSG00000061048 +244431 Sgcz MGI:MGI:2388820|Ensembl:ENSMUSG00000039539|Vega:OTTMUSG00000031650 +244448 Triml1 MGI:MGI:2687279|Ensembl:ENSMUSG00000031651|Vega:OTTMUSG00000061165 +244484 Wdr17 MGI:MGI:1924662|Ensembl:ENSMUSG00000039375|Vega:OTTMUSG00000026034 +244486 Adam29 MGI:MGI:2676326|Ensembl:ENSMUSG00000046258|Vega:OTTMUSG00000036482 +244495 Sgo2b MGI:MGI:3644562|Ensembl:ENSMUSG00000094443 +244548 Elmod2 MGI:MGI:2445165|Ensembl:ENSMUSG00000035151|Vega:OTTMUSG00000031104 +244550 Podnl1 MGI:MGI:2685352|Ensembl:ENSMUSG00000012889|Vega:OTTMUSG00000030575 +244551 Nanos3 MGI:MGI:2675387|Ensembl:ENSMUSG00000056155|Vega:OTTMUSG00000061277 +244556 Zfp791 MGI:MGI:3648473|Ensembl:ENSMUSG00000074194|Vega:OTTMUSG00000061405 +244562 Abcc12 MGI:MGI:2441679|Ensembl:ENSMUSG00000036872|Vega:OTTMUSG00000025883 +244579 Tox3 MGI:MGI:3039593|Ensembl:ENSMUSG00000043668|Vega:OTTMUSG00000040003 +244585 Rpgrip1l MGI:MGI:1920563|Ensembl:ENSMUSG00000033282|Vega:OTTMUSG00000024417 +244595 Ces1a MGI:MGI:3648919|Ensembl:ENSMUSG00000071047|Vega:OTTMUSG00000061540 +244608 Ccdc113 MGI:MGI:3606076|Ensembl:ENSMUSG00000036598|Vega:OTTMUSG00000061763 +244631 Pskh1 MGI:MGI:3528383|Ensembl:ENSMUSG00000048310|Vega:OTTMUSG00000029308 +244646 Pkd1l3 MGI:MGI:2664670|Ensembl:ENSMUSG00000048827|Vega:OTTMUSG00000061919 +244650 Phlpp2 MGI:MGI:2444928|Ensembl:ENSMUSG00000031732|Vega:OTTMUSG00000034048 +244653 Hydin MGI:MGI:2389007|Ensembl:ENSMUSG00000059854|Vega:OTTMUSG00000061892 +244654 Mtss1l MGI:MGI:3039591|Ensembl:ENSMUSG00000033763|Vega:OTTMUSG00000027473 +244666 Sprtn MGI:MGI:2685351|Ensembl:ENSMUSG00000031986|Vega:OTTMUSG00000061570 +244667 Disc1 MGI:MGI:2447658|Ensembl:ENSMUSG00000043051|Vega:OTTMUSG00000032471 +244668 Sipa1l2 MGI:MGI:2676970|Ensembl:ENSMUSG00000001995|Vega:OTTMUSG00000061592 +244672 Cwf19l2 MGI:MGI:1918023|Ensembl:ENSMUSG00000025898|Vega:OTTMUSG00000061663 +244682 Cntn5 MGI:MGI:3042287|Ensembl:ENSMUSG00000039488|Vega:OTTMUSG00000034705 +244694 Kdm4d MGI:MGI:3606484|Ensembl:ENSMUSG00000053914|Vega:OTTMUSG00000021069 +244698 Hephl1 MGI:MGI:2685355|Ensembl:ENSMUSG00000031936|Vega:OTTMUSG00000032787 +244701 Mtnr1b MGI:MGI:2181726|Ensembl:ENSMUSG00000050901|Vega:OTTMUSG00000043340 +244710 Gm4977 MGI:MGI:3648666 +244713 Zfp317 MGI:MGI:107775|Ensembl:ENSMUSG00000057551|Vega:OTTMUSG00000059647 +244721 Zfp846 MGI:MGI:1924012|Ensembl:ENSMUSG00000058192|Vega:OTTMUSG00000024767 +244723 Olfm2 MGI:MGI:3045350|Ensembl:ENSMUSG00000032172|Vega:OTTMUSG00000062980 +244745 Dpy19l1 MGI:MGI:1915685|Ensembl:ENSMUSG00000043067|Vega:OTTMUSG00000025711 +244757 Glb1l2 MGI:MGI:2388283|Ensembl:ENSMUSG00000036395|Vega:OTTMUSG00000028780 +244810 AW551984 MGI:MGI:2143322|Ensembl:ENSMUSG00000038112|Vega:OTTMUSG00000027425 +244813 Bsx MGI:MGI:2669849|Ensembl:ENSMUSG00000054360|Vega:OTTMUSG00000027431 +244853 Nxpe4 MGI:MGI:1924792|Ensembl:ENSMUSG00000044229|Vega:OTTMUSG00000063005 +244859 Ankk1 MGI:MGI:3045301|Ensembl:ENSMUSG00000032257|Vega:OTTMUSG00000063017 +244864 Layn MGI:MGI:2685357|Ensembl:ENSMUSG00000060594|Vega:OTTMUSG00000063077 +244867 Arhgap20 MGI:MGI:2445175|Ensembl:ENSMUSG00000053199|Vega:OTTMUSG00000024028 +244871 Zc3h12c MGI:MGI:3026959|Ensembl:ENSMUSG00000035164|Vega:OTTMUSG00000063090 +244879 Npat MGI:MGI:107605|Ensembl:ENSMUSG00000033054|Vega:OTTMUSG00000031590 +244882 Tnfaip8l3 MGI:MGI:2685363|Ensembl:ENSMUSG00000074345|Vega:OTTMUSG00000063198 +244885 Sh2d7 MGI:MGI:2441692|Ensembl:ENSMUSG00000046460|Vega:OTTMUSG00000030281 +244886 Tmem266 MGI:MGI:2142980|Ensembl:ENSMUSG00000032313|Vega:OTTMUSG00000024534 +244891 Scaper MGI:MGI:1925976|Ensembl:ENSMUSG00000034007|Vega:OTTMUSG00000063109 +244895 Peak1 MGI:MGI:2442366|Ensembl:ENSMUSG00000074305|Vega:OTTMUSG00000048386 +244911 C2cd4a MGI:MGI:3645763|Ensembl:ENSMUSG00000047990|Vega:OTTMUSG00000062685 +244913 Gm4978 MGI:MGI:3645765 +244923 Klhl31 MGI:MGI:3045305|Ensembl:ENSMUSG00000044938|Vega:OTTMUSG00000044856 +244954 Prss35 MGI:MGI:2444800|Ensembl:ENSMUSG00000033491|Vega:OTTMUSG00000045049 +244958 Mrap2 MGI:MGI:3609239|Ensembl:ENSMUSG00000042761|Vega:OTTMUSG00000024323 +244962 Snx14 MGI:MGI:2155664|Ensembl:ENSMUSG00000032422|Vega:OTTMUSG00000030828 +245000 Atr MGI:MGI:108028|Ensembl:ENSMUSG00000032409|Vega:OTTMUSG00000047295 +245007 Zbtb38 MGI:MGI:2442866|Ensembl:ENSMUSG00000040433|Vega:OTTMUSG00000033697 +245015 Gm518 MGI:MGI:2685364 +245020 Slc35g2 MGI:MGI:2685365|Ensembl:ENSMUSG00000070287|Vega:OTTMUSG00000048291 +245026 Col6a6 MGI:MGI:2444259|Ensembl:ENSMUSG00000043719|Vega:OTTMUSG00000049418 +245038 Dclk3 MGI:MGI:3039580|Ensembl:ENSMUSG00000032500|Vega:OTTMUSG00000027483 +245049 Myrip MGI:MGI:2384407|Ensembl:ENSMUSG00000041794|Vega:OTTMUSG00000023760 +245050 Fam198a MGI:MGI:3041196|Ensembl:ENSMUSG00000038233|Vega:OTTMUSG00000062694 +245109 Zscan4c MGI:MGI:2685243|Ensembl:ENSMUSG00000054272|Vega:OTTMUSG00000032953 +245126 Tarm1 MGI:MGI:2442280|Ensembl:ENSMUSG00000053338|Vega:OTTMUSG00000057721 +245128 AU018091 MGI:MGI:2142124|Ensembl:ENSMUSG00000054753|Vega:OTTMUSG00000057612 +245174 Zfp937 MGI:MGI:3644476|Ensembl:ENSMUSG00000060336|Vega:OTTMUSG00000015773 +245195 Retnlg MGI:MGI:2667763|Ensembl:ENSMUSG00000022651 +245240 9930111J21Rik2 MGI:MGI:3711310|Ensembl:ENSMUSG00000069892|Vega:OTTMUSG00000005540 +245263 Gm4981 MGI:MGI:3645498|Ensembl:ENSMUSG00000075045|Vega:OTTMUSG00000038789 +245269 Nim1k MGI:MGI:2442399|Ensembl:ENSMUSG00000095930 +245282 Apol10a MGI:MGI:3036238|Ensembl:ENSMUSG00000050982|Vega:OTTMUSG00000028116 +245290 Gm4982 MGI:MGI:3646925 +245297 Gm4983 MGI:MGI:3646928 +245305 B230307C23Rik MGI:MGI:3643396 +245308 Zdhhc19 MGI:MGI:2682948|Ensembl:ENSMUSG00000052363|Vega:OTTMUSG00000029127 +245347 Gm4984 MGI:MGI:3644533 +245350 AA414768 MGI:MGI:3035137 +245368 Zfp300 MGI:MGI:3045326|Ensembl:ENSMUSG00000031079|Vega:OTTMUSG00000017205 +245376 Gm4985 MGI:MGI:3648554 +245381 Sowahd MGI:MGI:3045274|Ensembl:ENSMUSG00000044400|Vega:OTTMUSG00000017107 +245386 Tmem255a MGI:MGI:3045722|Ensembl:ENSMUSG00000036502|Vega:OTTMUSG00000017235 +245391 Gm4986 MGI:MGI:3647545 +245403 Dcaf12l2 MGI:MGI:2445178|Ensembl:ENSMUSG00000050926|Vega:OTTMUSG00000017413 +245404 Dcaf12l1 MGI:MGI:2444462|Ensembl:ENSMUSG00000045284|Vega:OTTMUSG00000017414 +245405 Gm4987 MGI:MGI:3647751 +245423 Gm364 MGI:MGI:2685210|Ensembl:ENSMUSG00000079584|Vega:OTTMUSG00000017525 +245424 Gpr101 MGI:MGI:2685211|Ensembl:ENSMUSG00000036357|Vega:OTTMUSG00000017524 +245440 Gm4988 MGI:MGI:3647289 +245446 Slitrk4 MGI:MGI:2442509|Ensembl:ENSMUSG00000046699|Vega:OTTMUSG00000017598 +245450 Slitrk2 MGI:MGI:2679449|Ensembl:ENSMUSG00000036790|Vega:OTTMUSG00000017614 +245468 Pnma3 MGI:MGI:2180565|Ensembl:ENSMUSG00000046287|Vega:OTTMUSG00000017702 +245469 Pdzd4 MGI:MGI:2443483|Ensembl:ENSMUSG00000002006|Vega:OTTMUSG00000017680 +245472 Gm4989 MGI:MGI:3643860 +245474 Dkc1 MGI:MGI:1861727|Ensembl:ENSMUSG00000031403|Vega:OTTMUSG00000020788 +245492 4930595M18Rik MGI:MGI:3045300|Ensembl:ENSMUSG00000060673|Vega:OTTMUSG00000017894 +245502 Gm41 MGI:MGI:2684887 +245506 Ppp4r3c-ps MGI:MGI:3646205 +245509 4932429P05Rik MGI:MGI:3588287|Ensembl:ENSMUSG00000079513|Vega:OTTMUSG00000017951 +245511 4930415L06Rik MGI:MGI:3588286|Ensembl:ENSMUSG00000035387|Vega:OTTMUSG00000017956 +245516 Gm4990 MGI:MGI:3643282 +245522 Zc4h2 MGI:MGI:2679294|Ensembl:ENSMUSG00000035062|Vega:OTTMUSG00000018080 +245525 Hsf3 MGI:MGI:3045337|Ensembl:ENSMUSG00000045802|Vega:OTTMUSG00000018499 +245526 Pgr15l MGI:MGI:2676330|Ensembl:ENSMUSG00000031212|Vega:OTTMUSG00000018047 +245527 Eda2r MGI:MGI:2442860|Ensembl:ENSMUSG00000034457|Vega:OTTMUSG00000018046 +245532 Awat2 MGI:MGI:3045345|Ensembl:ENSMUSG00000031220|Vega:OTTMUSG00000018129 +245533 Awat1 MGI:MGI:3588200|Ensembl:ENSMUSG00000015665|Vega:OTTMUSG00000018287 +245536 Gm614 MGI:MGI:2685460|Ensembl:ENSMUSG00000090141|Vega:OTTMUSG00000018206 +245537 Nlgn3 MGI:MGI:2444609|Ensembl:ENSMUSG00000031302|Vega:OTTMUSG00000018201 +245545 Pabpc1l2a-ps MGI:MGI:3645788 +245555 C77370 MGI:MGI:2148050|Ensembl:ENSMUSG00000046449 +245566 Cypt2 MGI:MGI:2676331|Ensembl:ENSMUSG00000090132|Vega:OTTMUSG00000018112 +245572 Tbx22 MGI:MGI:2389465|Ensembl:ENSMUSG00000031241|Vega:OTTMUSG00000018237 +245573 Gm4991 MGI:MGI:3643043 +245575 Gm4992 MGI:MGI:3647043 +245576 Gm4993 MGI:MGI:3647205 +245578 Pcdh11x MGI:MGI:2442849|Ensembl:ENSMUSG00000034755|Vega:OTTMUSG00000018521 +245583 Tgif2lx1 MGI:MGI:2387796|Ensembl:ENSMUSG00000100133|Vega:OTTMUSG00000018465 +245595 Zfp711 MGI:MGI:3045342|Ensembl:ENSMUSG00000025529|Vega:OTTMUSG00000018456 +245596 Hdx MGI:MGI:2685226|Ensembl:ENSMUSG00000034551|Vega:OTTMUSG00000018434 +245598 4921511C20Rik MGI:MGI:2685229|Ensembl:ENSMUSG00000049815|Vega:OTTMUSG00000018635 +245600 Gm4994 MGI:MGI:3645787 +245607 Gprasp2 MGI:MGI:2442071|Ensembl:ENSMUSG00000072966|Vega:OTTMUSG00000018752 +245610 Nxf3 MGI:MGI:2685230|Ensembl:ENSMUSG00000057000|Vega:OTTMUSG00000018776 +245615 Kir3dl2 MGI:MGI:3612791|Ensembl:ENSMUSG00000057439|Vega:OTTMUSG00000018684 +245616 Kir3dl1 MGI:MGI:2652397|Ensembl:ENSMUSG00000031424|Vega:OTTMUSG00000016977 +245622 Fam199x MGI:MGI:2384304|Ensembl:ENSMUSG00000042595|Vega:OTTMUSG00000017505 +245631 Mum1l1 MGI:MGI:2445062|Ensembl:ENSMUSG00000042515|Vega:OTTMUSG00000018716 +245638 Tbc1d8b MGI:MGI:1918101|Ensembl:ENSMUSG00000042473|Vega:OTTMUSG00000018731 +245643 Frmpd3 MGI:MGI:3646547|Ensembl:ENSMUSG00000042425|Vega:OTTMUSG00000018844 +245650 Gucy2f MGI:MGI:105119|Ensembl:ENSMUSG00000042282|Vega:OTTMUSG00000018739 +245663 Gm4996 MGI:MGI:3646769 +245666 Iqsec2 MGI:MGI:3528396|Ensembl:ENSMUSG00000041115|Vega:OTTMUSG00000019682 +245670 Rragb MGI:MGI:3038613|Ensembl:ENSMUSG00000041658|Vega:OTTMUSG00000019332 +245671 Klf8 MGI:MGI:2442430|Ensembl:ENSMUSG00000041649|Vega:OTTMUSG00000019377 +245676 Gm4997 MGI:MGI:3643651|Ensembl:ENSMUSG00000045694 +245683 Klhl34 MGI:MGI:2685234|Ensembl:ENSMUSG00000047485|Vega:OTTMUSG00000019404 +245684 Cnksr2 MGI:MGI:2661175|Ensembl:ENSMUSG00000025658|Vega:OTTMUSG00000019390 +245688 Rbbp7 MGI:MGI:1194910|Ensembl:ENSMUSG00000031353|Vega:OTTMUSG00000017256 +245695 Tceanc MGI:MGI:2685236|Ensembl:ENSMUSG00000051224|Vega:OTTMUSG00000019552 +245704 Aliq4 MGI:MGI:2178585 +245707 Rvm MGI:MGI:1934624 +245827 Fat2 MGI:MGI:2685369|Ensembl:ENSMUSG00000055333|Vega:OTTMUSG00000005689 +245828 Trappc1 MGI:MGI:1098727|Ensembl:ENSMUSG00000049299|Vega:OTTMUSG00000005974 +245839 Gzmn MGI:MGI:2675494|Ensembl:ENSMUSG00000015443 +245841 Polr2h MGI:MGI:2384309|Ensembl:ENSMUSG00000021018|Vega:OTTMUSG00000035122 +245847 Amdhd2 MGI:MGI:2443978|Ensembl:ENSMUSG00000036820|Vega:OTTMUSG00000023853 +245855 BC026513 MGI:MGI:2652849 +245857 Ssh3 MGI:MGI:2683546|Ensembl:ENSMUSG00000034616 +245860 Atg9a MGI:MGI:2138446|Ensembl:ENSMUSG00000033124|Vega:OTTMUSG00000048480 +245865 Spag4 MGI:MGI:2444120|Ensembl:ENSMUSG00000038180|Vega:OTTMUSG00000016063 +245866 Ift52 MGI:MGI:2387217|Ensembl:ENSMUSG00000017858|Vega:OTTMUSG00000001063 +245867 Pcmtd2 MGI:MGI:1923927|Ensembl:ENSMUSG00000027589|Vega:OTTMUSG00000016836 +245877 Map7d1 MGI:MGI:2384297|Ensembl:ENSMUSG00000028849|Vega:OTTMUSG00000009353 +245880 Wasf3 MGI:MGI:2658986|Ensembl:ENSMUSG00000029636|Vega:OTTMUSG00000025851 +245884 Fam71f2 MGI:MGI:2141439|Ensembl:ENSMUSG00000079652|Vega:OTTMUSG00000035850 +245886 Ankrd27 MGI:MGI:2444103|Ensembl:ENSMUSG00000034867|Vega:OTTMUSG00000049776 +245902 Ccdc15 MGI:MGI:2444488|Ensembl:ENSMUSG00000034303|Vega:OTTMUSG00000063059 +245904 Lcl MGI:MGI:2149028 +245905 Dilp3 MGI:MGI:1934609 +245906 Dilp4 MGI:MGI:1934610 +245944 Vps54 MGI:MGI:2178798|Ensembl:ENSMUSG00000020128|Vega:OTTMUSG00000005242 +245945 Rbm47 MGI:MGI:2384294|Ensembl:ENSMUSG00000070780|Vega:OTTMUSG00000022238 +245967 T(6F3;10B2)40Dn MGI:MGI:2179042 +245968 T(6F3;10B2)40Dn MGI:MGI:2179043 +246048 Chodl MGI:MGI:2179069|Ensembl:ENSMUSG00000022860|Vega:OTTMUSG00000019947 +246049 Slc36a2 MGI:MGI:1891430|Ensembl:ENSMUSG00000020264|Vega:OTTMUSG00000005685 +246079 Defb9 MGI:MGI:2179198|Ensembl:ENSMUSG00000047390|Vega:OTTMUSG00000020782 +246080 Defb7 MGI:MGI:2179200|Ensembl:ENSMUSG00000037790|Vega:OTTMUSG00000020722 +246081 Defb11 MGI:MGI:2179197|Ensembl:ENSMUSG00000045337|Vega:OTTMUSG00000020784 +246082 Defb15 MGI:MGI:2179202|Ensembl:ENSMUSG00000048500|Vega:OTTMUSG00000020830 +246083 Defb13 MGI:MGI:2179203|Ensembl:ENSMUSG00000044222|Vega:OTTMUSG00000020827 +246084 Defb35 MGI:MGI:2179204|Ensembl:ENSMUSG00000058052|Vega:OTTMUSG00000020829 +246085 Defb10 MGI:MGI:2179205|Ensembl:ENSMUSG00000044743|Vega:OTTMUSG00000020783 +246086 Onecut3 MGI:MGI:1891409|Ensembl:ENSMUSG00000045518|Vega:OTTMUSG00000040151 +246087 Ckds MGI:MGI:2179234 +246088 Mtes1 MGI:MGI:1931151 +246102 Rttn MGI:MGI:2179288|Ensembl:ENSMUSG00000023066 +246103 Atxn7 MGI:MGI:2179277|Ensembl:ENSMUSG00000021738 +246104 Rhbdl3 MGI:MGI:2179276|Ensembl:ENSMUSG00000017692|Vega:OTTMUSG00000000214 +246105 Aggr2 MGI:MGI:2179241 +246106 Aggr1 MGI:MGI:2179240 +246107 Lifespan1 MGI:MGI:2179244 +246108 Lifespan2 MGI:MGI:2179245 +246109 Lifespan3 MGI:MGI:2179246 +246110 Naq1 MGI:MGI:2179258 +246133 Kcne2 MGI:MGI:1891123|Ensembl:ENSMUSG00000039672|Vega:OTTMUSG00000019966 +246154 Vasn MGI:MGI:2177651|Ensembl:ENSMUSG00000039646|Vega:OTTMUSG00000024383 +246155 L1Md-Gf21 MGI:MGI:2178789 +246156 L1Md-Gf23 MGI:MGI:2178790 +246157 L1Md-Gf26 MGI:MGI:2178792 +246158 L1Md-Gf27 MGI:MGI:2178793 +246159 L1Md-Gf36 MGI:MGI:2178794 +246160 L1Md-Gf43 MGI:MGI:2178795 +246161 L1Md-Gf56 MGI:MGI:2178797 +246162 L1Md-Gf62 MGI:MGI:2178803 +246163 L1Md-Gf68 MGI:MGI:2178804 +246164 L1Md-Gf71 MGI:MGI:2178806 +246165 L1Md-Gf78 MGI:MGI:2178808 +246166 L1Md-Gf82 MGI:MGI:2178811 +246167 L1Md-Gf84 MGI:MGI:2178812 +246168 L1Md-Gf251 MGI:MGI:2178813 +246169 L1Md-Gf253 MGI:MGI:2178814 +246177 Myo1g MGI:MGI:1927091|Ensembl:ENSMUSG00000020437|Vega:OTTMUSG00000005117 +246178 Msu MGI:MGI:1890776 +246179 Fktn MGI:MGI:2179507|Ensembl:ENSMUSG00000028414|Vega:OTTMUSG00000007009 +246189 L1Md-Gf13 MGI:MGI:2178783 +246190 Otoa MGI:MGI:2149209|Ensembl:ENSMUSG00000034990|Vega:OTTMUSG00000036710 +246192 Ltnr3 MGI:MGI:1891001 +246193 Ltnr4 MGI:MGI:1891002 +246194 Ltnr5 MGI:MGI:1891003 +246195 Ltnr6 MGI:MGI:1891004 +246196 Zfp277 MGI:MGI:1890393|Ensembl:ENSMUSG00000055917 +246197 Vcbd1 MGI:MGI:1891114 +246198 Mllt6 MGI:MGI:1935145|Ensembl:ENSMUSG00000038437|Vega:OTTMUSG00000002741 +246207 L1Md-Gf46 MGI:MGI:2178796 +246221 Mpst MGI:MGI:2179733|Ensembl:ENSMUSG00000071711 +246228 Vwa1 MGI:MGI:2179729|Ensembl:ENSMUSG00000042116|Vega:OTTMUSG00000010849 +246229 Bivm MGI:MGI:2179809|Ensembl:ENSMUSG00000041684|Vega:OTTMUSG00000023025 +246256 Fcgr4 MGI:MGI:2179523|Ensembl:ENSMUSG00000059089|Vega:OTTMUSG00000022168 +246257 Ovca2 MGI:MGI:2179725|Ensembl:ENSMUSG00000038268|Vega:OTTMUSG00000006195 +246277 Csad MGI:MGI:2180098|Ensembl:ENSMUSG00000023044 +246278 Cd207 MGI:MGI:2180021|Ensembl:ENSMUSG00000034783|Vega:OTTMUSG00000058011 +246293 Klhl8 MGI:MGI:2179430|Ensembl:ENSMUSG00000029312|Vega:OTTMUSG00000022027 +246313 Prokr2 MGI:MGI:2181363|Ensembl:ENSMUSG00000050558|Vega:OTTMUSG00000015549 +246316 Lgi2 MGI:MGI:2180196|Ensembl:ENSMUSG00000039252|Vega:OTTMUSG00000054573 +246317 Neto1 MGI:MGI:2180216|Ensembl:ENSMUSG00000050321 +246691 Prok1 MGI:MGI:2180370|Ensembl:ENSMUSG00000070368|Vega:OTTMUSG00000052945 +246694 Hps5 MGI:MGI:2180307|Ensembl:ENSMUSG00000014418|Vega:OTTMUSG00000024390 +246696 Slc25a28 MGI:MGI:2180509|Ensembl:ENSMUSG00000040414 +246700 Defb19 MGI:MGI:2385955|Ensembl:ENSMUSG00000050645|Vega:OTTMUSG00000015831 +246703 Naxe MGI:MGI:2180167|Ensembl:ENSMUSG00000028070|Vega:OTTMUSG00000051870 +246707 Emilin2 MGI:MGI:2389136|Ensembl:ENSMUSG00000024053 +246709 Rgs13 MGI:MGI:2180585|Ensembl:ENSMUSG00000051079|Vega:OTTMUSG00000020880 +246710 Rhobtb2 MGI:MGI:2180557|Ensembl:ENSMUSG00000022075 +246722 Gy MGI:MGI:2180716 +246727 Oas3 MGI:MGI:2180850|Ensembl:ENSMUSG00000032661|Vega:OTTMUSG00000036440 +246728 Oas2 MGI:MGI:2180852|Ensembl:ENSMUSG00000032690|Vega:OTTMUSG00000025348 +246729 Oas1h MGI:MGI:2180853|Ensembl:ENSMUSG00000001168|Vega:OTTMUSG00000026828 +246730 Oas1a MGI:MGI:2180860|Ensembl:ENSMUSG00000052776|Vega:OTTMUSG00000026831 +246735 AY074887 MGI:MGI:3575512|Ensembl:ENSMUSG00000044820|Vega:OTTMUSG00000036072 +246738 Dnajc28 MGI:MGI:2181053|Ensembl:ENSMUSG00000039763|Vega:OTTMUSG00000019887 +246739 Rends MGI:MGI:2181070 +246740 Renf1 MGI:MGI:2181044 +246741 Renf2 MGI:MGI:2181045 +246746 Cd300lf MGI:MGI:2442359|Ensembl:ENSMUSG00000047798|Vega:OTTMUSG00000003642 +246747 Adig MGI:MGI:2675492|Ensembl:ENSMUSG00000044405|Vega:OTTMUSG00000015927 +246749 Esmr MGI:MGI:2181163 +246779 Il27 MGI:MGI:2384409|Ensembl:ENSMUSG00000044701|Vega:OTTMUSG00000029446 +246782 Atpaf2 MGI:MGI:2180561|Ensembl:ENSMUSG00000042709|Vega:OTTMUSG00000005820 +246787 Slc5a2 MGI:MGI:2181411|Ensembl:ENSMUSG00000030781|Vega:OTTMUSG00000026291 +246788 Trpv3 MGI:MGI:2181407|Ensembl:ENSMUSG00000043029|Vega:OTTMUSG00000006137 +246791 Obox3 MGI:MGI:2149032|Ensembl:ENSMUSG00000066772|Vega:OTTMUSG00000037626 +246792 Obox2 MGI:MGI:2149033|Ensembl:ENSMUSG00000074369|Vega:OTTMUSG00000035502 +252828 Obox4 MGI:MGI:2149034 +252829 Obox5 MGI:MGI:2149035|Ensembl:ENSMUSG00000074366|Vega:OTTMUSG00000037567 +252830 Obox6 MGI:MGI:2149036|Ensembl:ENSMUSG00000041583|Vega:OTTMUSG00000032721 +252837 Ackr4 MGI:MGI:2181676|Ensembl:ENSMUSG00000079355|Vega:OTTMUSG00000049290 +252838 Tox MGI:MGI:2181659|Ensembl:ENSMUSG00000041272|Vega:OTTMUSG00000004332 +252844 Nlk-ps1 MGI:MGI:2181687 +252864 Dusp15 MGI:MGI:1934928|Ensembl:ENSMUSG00000042662|Vega:OTTMUSG00000015860 +252866 Adam34 MGI:MGI:2181992|Ensembl:ENSMUSG00000079058|Vega:OTTMUSG00000061173 +252868 Odf4 MGI:MGI:2182079|Ensembl:ENSMUSG00000032921|Vega:OTTMUSG00000005951 +252870 Usp7 MGI:MGI:2182061|Ensembl:ENSMUSG00000022710|Vega:OTTMUSG00000035130 +252875 Mios MGI:MGI:2182066|Ensembl:ENSMUSG00000042447|Vega:OTTMUSG00000023501 +252876 Gin1 MGI:MGI:2182036|Ensembl:ENSMUSG00000026333|Vega:OTTMUSG00000021440 +252903 Ap1s3 MGI:MGI:1891304|Ensembl:ENSMUSG00000054702|Vega:OTTMUSG00000034766 +252904 Vmn1r69 MGI:MGI:2182253|Ensembl:ENSMUSG00000091662|Vega:OTTMUSG00000038517 +252905 Vmn1r72 MGI:MGI:2182256|Ensembl:ENSMUSG00000095430|Vega:OTTMUSG00000038273 +252906 Vmn1r189 MGI:MGI:2182257|Ensembl:ENSMUSG00000099611|Vega:OTTMUSG00000000472 +252907 Vmn1r192 MGI:MGI:2182260|Ensembl:ENSMUSG00000099787|Vega:OTTMUSG00000000474 +252908 Vmn1r190-ps MGI:MGI:2182261 +252909 Vmn1r85 MGI:MGI:2182262|Ensembl:ENSMUSG00000070817|Vega:OTTMUSG00000038212 +252910 Vmn1r71 MGI:MGI:2182255|Ensembl:ENSMUSG00000059206|Vega:OTTMUSG00000038522 +252912 Vmn1r188 MGI:MGI:2182259|Ensembl:ENSMUSG00000069299|Vega:OTTMUSG00000000459 +252966 Cables2 MGI:MGI:2182335|Ensembl:ENSMUSG00000038990|Vega:OTTMUSG00000016283 +252967 Ropn1l MGI:MGI:2182357|Ensembl:ENSMUSG00000022236 +252972 Tpcn1 MGI:MGI:2182472|Ensembl:ENSMUSG00000032741|Vega:OTTMUSG00000056260 +252973 Grhl2 MGI:MGI:2182543|Ensembl:ENSMUSG00000022286|Vega:OTTMUSG00000030880 +252974 Tspear MGI:MGI:2671932|Ensembl:ENSMUSG00000069581|Vega:OTTMUSG00000020510 +257630 Il17f MGI:MGI:2676631|Ensembl:ENSMUSG00000041872|Vega:OTTMUSG00000048286 +257632 Nod2 MGI:MGI:2429397|Ensembl:ENSMUSG00000055994|Vega:OTTMUSG00000029844 +257633 Acsf3 MGI:MGI:2182591|Ensembl:ENSMUSG00000015016|Vega:OTTMUSG00000061867 +257635 Sdsl MGI:MGI:2182607|Ensembl:ENSMUSG00000029596|Vega:OTTMUSG00000025284 +257662 Olfr1290 MGI:MGI:3031124|Ensembl:ENSMUSG00000095809|Vega:OTTMUSG00000015087 +257664 Olfr773 MGI:MGI:3030607|Ensembl:ENSMUSG00000096000|Vega:OTTMUSG00000056554 +257665 Olfr1506 MGI:MGI:3031340|Ensembl:ENSMUSG00000075064|Vega:OTTMUSG00000014234 +257666 Olfr772 MGI:MGI:3030606|Ensembl:ENSMUSG00000107662|Vega:OTTMUSG00000056553 +257667 Olfr769 MGI:MGI:3030603|Ensembl:ENSMUSG00000042801|Vega:OTTMUSG00000056482 +257674 GA_x5J8B7U259D-794-444 - +257680 GA_x5J8B7TTCP5-695-189 - +257681 GA_x5J8B7TT63N-1148-873 - +257685 GA_x5J8B7W5P47-106198-105851 - +257687 GA_x5J8B7W3KVV-33993-34050 - +257695 GA_x5J8B7TTEHJ-1-399 - +257697 GA_x5J8B7TRQ0A-1229-891 - +257704 GA_x5J8B7TU1B9-1178-1387 - +257726 Olfr751-ps1 MGI:MGI:3030585 +257734 Olfr1355 MGI:MGI:3031189|Ensembl:ENSMUSG00000062873|Vega:OTTMUSG00000056725 +257755 Olfr833-ps1 MGI:MGI:3030667 +257756 Olfr838-ps1 MGI:MGI:3030672 +257757 Olfr840-ps1 MGI:MGI:3030674 +257768 Olfr1488-ps1 MGI:MGI:3031322 +257770 Olfr797-ps1 MGI:MGI:3030631 +257771 Olfr795-ps1 MGI:MGI:3030629 +257772 Gm5001 MGI:MGI:3643923 +257773 Gm5002 MGI:MGI:3643924 +257774 Olfr673-ps1 MGI:MGI:3030507 +257777 Olfr454-ps1 MGI:MGI:3030288 +257778 Olfr436-ps1 MGI:MGI:3030270 +257779 Olfr439-ps1 MGI:MGI:3030273 +257780 Olfr442-ps1 MGI:MGI:3030276 +257781 Olrf445-ps1 MGI:MGI:3030279 +257785 Olfr1236-ps1 MGI:MGI:3031070 +257787 Gm38406 MGI:MGI:5621291 +257789 Gm5010 MGI:MGI:3646843 +257790 Olfr927-ps1 MGI:MGI:3030761 +257791 Olfr929-ps1 MGI:MGI:3030763 +257792 Olfr931-ps1 MGI:MGI:3030765 +257793 Olfr940-ps1 MGI:MGI:3030774 +257794 Olfr962-ps1 MGI:MGI:3030796 +257795 Olfr946-ps1 MGI:MGI:3030780 +257796 Olfr879-ps1 MGI:MGI:3030713 +257799 Olfr1409-ps1 MGI:MGI:3031243 +257800 Olfr1407-ps1 MGI:MGI:3031241 +257805 Olfr756-ps1 MGI:MGI:3030590 +257807 Olfr757-ps1 MGI:MGI:3030591 +257810 Olfr269-ps1 MGI:MGI:3030103 +257811 Olfr1400-ps1 MGI:MGI:3031234 +257812 Olfr1007-ps1 MGI:MGI:3030841 +257813 Olfr1005-ps1 MGI:MGI:3030839 +257814 Olfr1003-ps1 MGI:MGI:3030837 +257816 Olfr989-ps1 MGI:MGI:3030823 +257817 Olfr277-ps1 MGI:MGI:3030111 +257819 Olfr1291-ps1 MGI:MGI:3031125 +257829 Gm5023 MGI:MGI:3645029 +257831 Olfr1108-ps1 MGI:MGI:3030942 +257832 Olfr1092-ps1 MGI:MGI:3030926 +257833 Olfr1144-ps1 MGI:MGI:3030978 +257834 Olfr1139-ps1 MGI:MGI:3030973 +257835 Gm5027 MGI:MGI:3643392 +257836 Olfr660-ps1 MGI:MGI:3030494 +257838 Olfr1319-ps1 MGI:MGI:3031153 +257840 Olfr1017-ps1 MGI:MGI:3030851 +257844 Olfr540-ps1 MGI:MGI:3030374 +257845 Olfr542-ps1 MGI:MGI:3030376 +257846 Olfr1345-ps1 MGI:MGI:3031179 +257847 Gm12855 MGI:MGI:3649662 +257848 Gm21942 MGI:MGI:5439393 +257850 Olfr416-ps1 MGI:MGI:3030250 +257851 Olfr431-ps1 MGI:MGI:3030265 +257852 Gm20553 MGI:MGI:5295660 +257854 Gm20734 MGI:MGI:5434090 +257855 Gm5034 MGI:MGI:3648000 +257863 Gm5035 MGI:MGI:3644624 +257871 Olfr1372-ps1 MGI:MGI:3031206 +257872 Olfr835 MGI:MGI:3030669|Ensembl:ENSMUSG00000045204|Vega:OTTMUSG00000061201 +257875 Olfr1116 MGI:MGI:3030950|Ensembl:ENSMUSG00000070855|Vega:OTTMUSG00000013778 +257876 Olfr400-ps1 MGI:MGI:3030234 +257877 Olfr717-ps1 MGI:MGI:3030551 +257878 Olfr752-ps1 MGI:MGI:3030586 +257879 Olfr375-ps1 MGI:MGI:3030209 +257880 Olfr1066 MGI:MGI:3030900|Ensembl:ENSMUSG00000075181|Vega:OTTMUSG00000013610 +257881 Olfr205 MGI:MGI:3030039|Ensembl:ENSMUSG00000094422|Vega:OTTMUSG00000059132 +257882 Olfr1344 MGI:MGI:3031178|Ensembl:ENSMUSG00000090824|Vega:OTTMUSG00000035162 +257883 Olfr1357 MGI:MGI:3031191|Ensembl:ENSMUSG00000071185|Vega:OTTMUSG00000056723 +257884 Olfr744 MGI:MGI:3030578|Ensembl:ENSMUSG00000053815|Vega:OTTMUSG00000058486 +257885 Olfr885 MGI:MGI:3030719|Ensembl:ENSMUSG00000096424|Vega:OTTMUSG00000061810 +257886 Olfr225 MGI:MGI:3030059|Ensembl:ENSMUSG00000044061 +257887 Olfr1200 MGI:MGI:3031034|Ensembl:ENSMUSG00000075115|Vega:OTTMUSG00000014049 +257888 Olfr1386 MGI:MGI:3031220|Ensembl:ENSMUSG00000108167|Vega:OTTMUSG00000005562 +257889 Olfr132 MGI:MGI:2177515|Ensembl:ENSMUSG00000067186|Vega:OTTMUSG00000037356 +257890 Olfr12 MGI:MGI:107863|Ensembl:ENSMUSG00000061616|Vega:OTTMUSG00000048569 +257891 Olfr479 MGI:MGI:3030313|Ensembl:ENSMUSG00000043855|Vega:OTTMUSG00000059961 +257892 Olfr324 MGI:MGI:3030158|Ensembl:ENSMUSG00000056564|Vega:OTTMUSG00000007530 +257893 Olfr105-ps MGI:MGI:2177488 +257896 Olfr1171-ps1 MGI:MGI:3031005 +257898 Olfr867 MGI:MGI:3030701|Ensembl:ENSMUSG00000044454|Vega:OTTMUSG00000061728 +257899 Olfr1000 MGI:MGI:3030834|Ensembl:ENSMUSG00000075215|Vega:OTTMUSG00000013506 +257900 Olfr1024 MGI:MGI:3030858|Ensembl:ENSMUSG00000075206|Vega:OTTMUSG00000013585 +257901 Olfr1096-ps1 MGI:MGI:3030930 +257902 Olfr704 MGI:MGI:3030538|Ensembl:ENSMUSG00000073900|Vega:OTTMUSG00000059720 +257903 Olfr977-ps1 MGI:MGI:3030811 +257904 Olfr294 MGI:MGI:3030128|Ensembl:ENSMUSG00000062042|Vega:OTTMUSG00000037774 +257905 Olfr298 MGI:MGI:3030132|Ensembl:ENSMUSG00000062878|Vega:OTTMUSG00000037769 +257906 Olfr293 MGI:MGI:3030127|Ensembl:ENSMUSG00000063394|Vega:OTTMUSG00000037775 +257907 Olfr1558-ps1 MGI:MGI:3031392 +257908 Olfr115 MGI:MGI:2177498|Ensembl:ENSMUSG00000092413|Vega:OTTMUSG00000037464 +257909 Olfr735 MGI:MGI:3030569|Ensembl:ENSMUSG00000046210 +257910 Olfr671 MGI:MGI:3030505|Ensembl:ENSMUSG00000094531|Vega:OTTMUSG00000060551 +257911 Olfr892-ps1 MGI:MGI:3030726 +257912 Olfr948 MGI:MGI:3030782|Ensembl:ENSMUSG00000057349|Vega:OTTMUSG00000062284 +257913 Olfr141 MGI:MGI:2177524|Ensembl:ENSMUSG00000078420|Vega:OTTMUSG00000013697 +257914 Olfr663 MGI:MGI:3030497|Ensembl:ENSMUSG00000109806|Vega:OTTMUSG00000060532 +257915 Olfr1016 MGI:MGI:3030850|Ensembl:ENSMUSG00000075209|Vega:OTTMUSG00000013559 +257916 Olfr1031 MGI:MGI:3030865|Ensembl:ENSMUSG00000043267|Vega:OTTMUSG00000013588 +257917 Olfr314 MGI:MGI:3030148|Ensembl:ENSMUSG00000059504|Vega:OTTMUSG00000005765 +257918 Olfr817-ps1 MGI:MGI:3030651 +257919 Olfr467 MGI:MGI:3030301|Ensembl:ENSMUSG00000066242|Vega:OTTMUSG00000059947 +257920 Olfr404-ps1 MGI:MGI:3030238 +257921 Olfr1229 MGI:MGI:3031063|Ensembl:ENSMUSG00000075095|Vega:OTTMUSG00000014014 +257924 Olfr947-ps1 MGI:MGI:3030781|Ensembl:ENSMUSG00000111190|Vega:OTTMUSG00000062283 +257925 Olfr106-ps MGI:MGI:2177489 +257926 Olfr544 MGI:MGI:3030378|Ensembl:ENSMUSG00000043925|Vega:OTTMUSG00000059871 +257928 Olfr844 MGI:MGI:3030678 +257929 Olfr299 MGI:MGI:3030133|Ensembl:ENSMUSG00000020168|Vega:OTTMUSG00000037768 +257931 Olfr317 MGI:MGI:3030151|Ensembl:ENSMUSG00000060030|Vega:OTTMUSG00000005747 +257932 Olfr332 MGI:MGI:3030166|Ensembl:ENSMUSG00000050813|Vega:OTTMUSG00000005740 +257933 Olfr1089 MGI:MGI:3030923|Ensembl:ENSMUSG00000111711|Vega:OTTMUSG00000013672 +257935 Olfr1287 MGI:MGI:3031121|Ensembl:ENSMUSG00000095586|Vega:OTTMUSG00000015075 +257936 Olfr1028 MGI:MGI:3031368|Ensembl:ENSMUSG00000057207|Vega:OTTMUSG00000013599 +257937 Olfr1192-ps1 MGI:MGI:3031026 +257938 Olfr1419 MGI:MGI:3031253|Ensembl:ENSMUSG00000067545|Vega:OTTMUSG00000059431 +257939 Olfr527 MGI:MGI:3030361|Ensembl:ENSMUSG00000062782|Vega:OTTMUSG00000060581 +257941 Olfr1042 MGI:MGI:3030876|Ensembl:ENSMUSG00000075202|Vega:OTTMUSG00000013655 +257942 Olfr379-ps1 MGI:MGI:3030213 +257943 Olfr285 MGI:MGI:3030119|Ensembl:ENSMUSG00000062037|Vega:OTTMUSG00000058678 +257947 Olfr543 MGI:MGI:3030377|Ensembl:ENSMUSG00000044814|Vega:OTTMUSG00000059870 +257948 Olfr104-ps MGI:MGI:2177487 +257949 Olfr634-ps1 MGI:MGI:3030468 +257950 Olfr1039 MGI:MGI:3030873|Ensembl:ENSMUSG00000075204|Vega:OTTMUSG00000013641 +257951 Olfr987 MGI:MGI:3030821|Ensembl:ENSMUSG00000075223|Vega:OTTMUSG00000013483 +257952 Olfr1332-ps1 MGI:MGI:3031166 +257954 Olfr1555-ps1 MGI:MGI:3031389 +257956 Olfr1307 MGI:MGI:3031141|Ensembl:ENSMUSG00000094747|Vega:OTTMUSG00000015117 +257957 Olfr1068-ps1 MGI:MGI:3030902 +257958 Olfr301 MGI:MGI:3030135|Ensembl:ENSMUSG00000061549|Vega:OTTMUSG00000037766 +257959 Olfr1537 MGI:MGI:3031371|Ensembl:ENSMUSG00000096109|Vega:OTTMUSG00000062280 +257960 Olfr210-ps1 MGI:MGI:3030044 +257961 Olfr1432 MGI:MGI:3031266|Ensembl:ENSMUSG00000109022|Vega:OTTMUSG00000042678 +257962 Olfr222 MGI:MGI:3030056|Ensembl:ENSMUSG00000059610|Vega:OTTMUSG00000005794 +257963 Olfr857 MGI:MGI:3030691|Ensembl:ENSMUSG00000094678 +257967 Olfr1551-ps1 MGI:MGI:3031385 +257968 Olfr252-ps1 MGI:MGI:3030086 +257969 Olfr1374-ps1 MGI:MGI:3031208 +257971 Olfr1382 MGI:MGI:3031216|Ensembl:ENSMUSG00000063827|Vega:OTTMUSG00000005558 +257972 Olfr193 MGI:MGI:3030027|Ensembl:ENSMUSG00000060057|Vega:OTTMUSG00000059121 +257973 Olfr207 MGI:MGI:3030041 +257974 Olfr1053 MGI:MGI:3030887|Ensembl:ENSMUSG00000075192|Vega:OTTMUSG00000013534 +257975 Olfr598 MGI:MGI:3030432|Ensembl:ENSMUSG00000073951|Vega:OTTMUSG00000019024 +257976 Olfr602-ps1 MGI:MGI:3030436 +257978 Olfr1322 MGI:MGI:3031156|Ensembl:ENSMUSG00000056281|Vega:OTTMUSG00000017799 +257979 Olfr1281 MGI:MGI:3031115|Ensembl:ENSMUSG00000095156|Vega:OTTMUSG00000015193 +257980 Olfr1275 MGI:MGI:3031109|Ensembl:ENSMUSG00000074966|Vega:OTTMUSG00000015189 +257981 Olfr680-ps1 MGI:MGI:3030514 +257982 Olfr721-ps1 MGI:MGI:3030555 +257983 Olfr783-ps1 MGI:MGI:3030617 +257984 Olfr1249 MGI:MGI:3031083|Ensembl:ENSMUSG00000075079|Vega:OTTMUSG00000014146 +257985 Olfr782 MGI:MGI:3030616|Ensembl:ENSMUSG00000095075|Vega:OTTMUSG00000056563 +257986 Olfr1547-ps1 MGI:MGI:3031381 +257989 Olfr1073-ps1 MGI:MGI:3030907 +257991 Olfr334-ps1 MGI:MGI:3030168 +257992 Olfr1430-ps1 MGI:MGI:3031264 +257993 Olfr956-ps1 MGI:MGI:3030790 +257994 Olfr886-ps1 MGI:MGI:3030720 +257995 Olfr882-ps1 MGI:MGI:3030716 +257996 Olfr884 MGI:MGI:3030718|Ensembl:ENSMUSG00000095893|Vega:OTTMUSG00000042489 +257997 Olfr737-ps1 MGI:MGI:3030571 +257998 Olfr997-ps1 MGI:MGI:3030831 +257999 Olfr349-ps1 MGI:MGI:3030183 +258000 Olfr1545-ps1 MGI:MGI:3031379 +258001 Olfr966-ps1 MGI:MGI:3030800 +258002 Olfr1119-ps1 MGI:MGI:3030953 +258003 Olfr1142-ps1 MGI:MGI:3030976 +258004 Olfr1435-ps1 MGI:MGI:3031269 +258005 Olfr1422-ps1 MGI:MGI:3031256 +258006 Olfr718-ps1 MGI:MGI:3030552 +258008 Olfr1513 MGI:MGI:3031347|Ensembl:ENSMUSG00000095030|Vega:OTTMUSG00000053557 +258009 Olfr990-ps1 MGI:MGI:3030824 +258011 Olfr184-ps1 MGI:MGI:3030018 +258012 Olfr1159-ps1 MGI:MGI:3030993 +258013 Olfr925-ps1 MGI:MGI:3030759 +258014 Olfr941-ps1 MGI:MGI:3030775 +258015 Olfr1439-ps1 MGI:MGI:3031273 +258016 Olfr453 MGI:MGI:3030287|Ensembl:ENSMUSG00000095831|Vega:OTTMUSG00000057453 +258017 Olfr451-ps1 MGI:MGI:3030285 +258018 Olfr163-ps1 MGI:MGI:3029997 +258019 Olfr212 MGI:MGI:3030046|Ensembl:ENSMUSG00000053251|Vega:OTTMUSG00000057303 +258020 Olfr213 MGI:MGI:3030047|Ensembl:ENSMUSG00000081649|Vega:OTTMUSG00000057304 +258022 Olfr1318 MGI:MGI:3031152|Ensembl:ENSMUSG00000049758|Vega:OTTMUSG00000015118 +258023 Olfr1306 MGI:MGI:3031140|Ensembl:ENSMUSG00000096566|Vega:OTTMUSG00000015115 +258025 Olfr1211 MGI:MGI:3031045|Ensembl:ENSMUSG00000075112|Vega:OTTMUSG00000014046 +258026 Olfr1224-ps1 MGI:MGI:3031058 +258027 Olfr1385 MGI:MGI:3031219|Ensembl:ENSMUSG00000059729|Vega:OTTMUSG00000005555 +258028 Olfr901 MGI:MGI:3030735|Ensembl:ENSMUSG00000052058|Vega:OTTMUSG00000062120 +258030 Olfr896-ps1 MGI:MGI:3030730 +258033 Olfr189-ps1 MGI:MGI:3030023 +258035 Olfr191 MGI:MGI:3030025|Ensembl:ENSMUSG00000094539|Vega:OTTMUSG00000058844 +258036 Olfr198 MGI:MGI:3030032|Ensembl:ENSMUSG00000052537|Vega:OTTMUSG00000059126 +258039 Olfr728 MGI:MGI:3030562|Ensembl:ENSMUSG00000050030|Vega:OTTMUSG00000058470 +258041 Olfr485 MGI:MGI:3030319|Ensembl:ENSMUSG00000108995|Vega:OTTMUSG00000059968 +258042 Olfr487 MGI:MGI:3030321|Ensembl:ENSMUSG00000095929|Vega:OTTMUSG00000059971 +258043 Olfr326-ps1 MGI:MGI:3030160 +258044 Olfr333-ps1 MGI:MGI:3030167 +258046 Olfr951 MGI:MGI:3030785|Ensembl:ENSMUSG00000094269|Vega:OTTMUSG00000062342 +258048 Olfr759-ps1 MGI:MGI:3030593 +258049 Olfr755-ps1 MGI:MGI:3030589 +258050 Olfr754-ps1 MGI:MGI:3030588 +258051 Olfr93 MGI:MGI:2177476|Ensembl:ENSMUSG00000091601|Vega:OTTMUSG00000037325 +258052 Olfr753-ps1 MGI:MGI:3030587 +258053 Olfr496-ps1 MGI:MGI:3030330 +258054 Olfr501-ps1 MGI:MGI:3030335 +258055 Olfr524 MGI:MGI:3030358|Ensembl:ENSMUSG00000050366|Vega:OTTMUSG00000060576 +258056 Olfr533 MGI:MGI:3030367|Ensembl:ENSMUSG00000056883|Vega:OTTMUSG00000060477 +258057 Olfr162-ps1 MGI:MGI:3029996 +258058 Olfr858-ps1 MGI:MGI:3030692 +258059 Olfr1185-ps1 MGI:MGI:3031019 +258060 Olfr1181 MGI:MGI:3031015|Ensembl:ENSMUSG00000075125|Vega:OTTMUSG00000013992 +258064 Olfr316 MGI:MGI:3030150|Ensembl:ENSMUSG00000107677|Vega:OTTMUSG00000005748 +258065 Olfr312 MGI:MGI:3030146|Ensembl:ENSMUSG00000096806|Vega:OTTMUSG00000005764 +258067 Olfr1359 MGI:MGI:3031193|Ensembl:ENSMUSG00000108674|Vega:OTTMUSG00000000442 +258068 Olfr804 MGI:MGI:3030638|Ensembl:ENSMUSG00000095401|Vega:OTTMUSG00000056621 +258069 Olfr787 MGI:MGI:3030621|Ensembl:ENSMUSG00000096497|Vega:OTTMUSG00000056568 +258070 Olfr863-ps1 MGI:MGI:3030697 +258071 Olfr864-ps1 MGI:MGI:3030698 +258072 Olfr841-ps1 MGI:MGI:3030675 +258073 Olfr842-ps1 MGI:MGI:3030676 +258074 Olfr834 MGI:MGI:3030668|Ensembl:ENSMUSG00000095525|Vega:OTTMUSG00000061200 +258075 Olfr832 MGI:MGI:3030666|Ensembl:ENSMUSG00000095957|Vega:OTTMUSG00000061198 +258076 Olfr999-ps1 MGI:MGI:3030833 +258078 Olfr1001-ps1 MGI:MGI:3030835 +258081 Olfr1035-ps1 MGI:MGI:3030869 +258082 Olfr1027-ps1 MGI:MGI:3030861 +258083 Olfr1025-ps1 MGI:MGI:3030859 +258084 Olfr1103-ps1 MGI:MGI:3030937 +258085 Olfr1105 MGI:MGI:3030939|Ensembl:ENSMUSG00000075165|Vega:OTTMUSG00000013717 +258086 Olfr967 MGI:MGI:3030801|Ensembl:ENSMUSG00000055820|Vega:OTTMUSG00000062391 +258087 Olfr963 MGI:MGI:3030797|Ensembl:ENSMUSG00000064110|Vega:OTTMUSG00000062385 +258088 Olfr300-ps1 MGI:MGI:3030134 +258089 Olfr304 MGI:MGI:3030138|Ensembl:ENSMUSG00000062426|Vega:OTTMUSG00000037764 +258091 Olfr359-ps1 MGI:MGI:3030193 +258092 Olfr337-ps1 MGI:MGI:3030171 +258093 Olfr336-ps1 MGI:MGI:3030170 +258094 Olfr761 MGI:MGI:3030595|Ensembl:ENSMUSG00000109376|Vega:OTTMUSG00000037344 +258095 Olfr119 MGI:MGI:2177502|Ensembl:ENSMUSG00000059964|Vega:OTTMUSG00000037469 +258096 Olfr112 MGI:MGI:2177495|Ensembl:ENSMUSG00000051611|Vega:OTTMUSG00000037461 +258097 Olfr1500 MGI:MGI:3031334|Ensembl:ENSMUSG00000054526|Vega:OTTMUSG00000059637 +258098 Olfr1490 MGI:MGI:3031324|Ensembl:ENSMUSG00000061387|Vega:OTTMUSG00000059540 +258099 Olfr1149-ps1 MGI:MGI:3030983 +258100 Olfr1147-ps1 MGI:MGI:3030981 +258101 Olfr1137 MGI:MGI:3030971|Ensembl:ENSMUSG00000075150|Vega:OTTMUSG00000013845 +258102 Olfr1146-ps1 MGI:MGI:3030980 +258103 Olfr1152 MGI:MGI:3030986|Ensembl:ENSMUSG00000045225|Vega:OTTMUSG00000013876 +258104 Olfr1150-ps1 MGI:MGI:3030984 +258105 Olfr1162 MGI:MGI:3030996|Ensembl:ENSMUSG00000075139|Vega:OTTMUSG00000013905 +258106 Olfr443-ps1 MGI:MGI:3030277 +258107 Olfr440-ps1 MGI:MGI:3030274 +258108 Olfr1127-ps1 MGI:MGI:3030961 +258110 Olfr1117-ps1 MGI:MGI:3030951 +258111 Olfr1129 MGI:MGI:3030963|Ensembl:ENSMUSG00000062272|Vega:OTTMUSG00000013848 +258113 Olfr748 MGI:MGI:3030582|Ensembl:ENSMUSG00000060084|Vega:OTTMUSG00000058563 +258116 Olfr1438-ps1 MGI:MGI:3031272 +258117 Olfr1437 MGI:MGI:3031271|Ensembl:ENSMUSG00000096436|Vega:OTTMUSG00000059447 +258118 Olfr1460-ps1 MGI:MGI:3031294 +258119 Olfr1470-ps1 MGI:MGI:3031304 +258120 Olfr1463 MGI:MGI:3031297|Ensembl:ENSMUSG00000096365|Vega:OTTMUSG00000059499 +258121 Olfr1465 MGI:MGI:3031299|Ensembl:ENSMUSG00000062199|Vega:OTTMUSG00000059501 +258123 Olfr1474 MGI:MGI:3031308|Ensembl:ENSMUSG00000096273|Vega:OTTMUSG00000059511 +258124 Olfr1473-ps1 MGI:MGI:3031307 +258126 Olfr1452-ps1 MGI:MGI:3031286 +258127 Olfr407-ps1 MGI:MGI:3030241 +258128 Olfr405-ps1 MGI:MGI:3030239 +258129 Olfr408-ps1 MGI:MGI:3030242 +258131 Olfr409-ps1 MGI:MGI:3030243 +258134 Olfr426 MGI:MGI:3030260 +258135 Olfr597 MGI:MGI:3030431|Ensembl:ENSMUSG00000073952|Vega:OTTMUSG00000019056 +258136 Olfr517 MGI:MGI:3030351|Ensembl:ENSMUSG00000066240|Vega:OTTMUSG00000060094 +258137 Olfr647-ps1 MGI:MGI:3030481 +258139 Olfr591 MGI:MGI:3030425|Ensembl:ENSMUSG00000057461|Vega:OTTMUSG00000019017 +258140 Olfr567-ps1 MGI:MGI:3030401 +258141 Olfr579-ps1 MGI:MGI:3030413 +258142 Olfr565-ps1 MGI:MGI:3030399 +258143 Olfr637-ps1 MGI:MGI:3030471 +258144 Olfr636-ps1 MGI:MGI:3030470 +258146 Olfr709-ps1 MGI:MGI:3030543 +258147 Olfr675 MGI:MGI:3030509|Ensembl:ENSMUSG00000096773|Vega:OTTMUSG00000060555 +258148 Olfr789 MGI:MGI:3030623|Ensembl:ENSMUSG00000111273|Vega:OTTMUSG00000056570 +258150 Olfr792 MGI:MGI:3030626|Ensembl:ENSMUSG00000094496|Vega:OTTMUSG00000056573 +258151 Olfr1505 MGI:MGI:3031339|Ensembl:ENSMUSG00000062314|Vega:OTTMUSG00000059690 +258153 Olfr412 MGI:MGI:3030246|Ensembl:ENSMUSG00000058275|Vega:OTTMUSG00000006180 +258154 Olfr1029 MGI:MGI:3030863|Ensembl:ENSMUSG00000059873|Vega:OTTMUSG00000013595 +258155 Olfr1425 MGI:MGI:3031259|Ensembl:ENSMUSG00000067526|Vega:OTTMUSG00000059437 +258156 Olfr605 MGI:MGI:3030439|Ensembl:ENSMUSG00000109659|Vega:OTTMUSG00000019083 +258158 Olfr169 MGI:MGI:3030003|Ensembl:ENSMUSG00000068535|Vega:OTTMUSG00000058761 +258159 Olfr1331 MGI:MGI:3031165|Ensembl:ENSMUSG00000073769|Vega:OTTMUSG00000008770 +258160 Olfr685 MGI:MGI:3030519|Ensembl:ENSMUSG00000047794|Vega:OTTMUSG00000060650 +258161 Olfr489-ps1 MGI:MGI:3030323 +258162 Olfr500-ps1 MGI:MGI:3030334 +258163 Olfr504 MGI:MGI:3030338|Ensembl:ENSMUSG00000060105|Vega:OTTMUSG00000059994 +258164 Olfr505-ps1 MGI:MGI:3030339 +258165 Olfr965 MGI:MGI:3030799|Ensembl:ENSMUSG00000095839|Vega:OTTMUSG00000062388 +258166 Olfr988 MGI:MGI:3030822|Ensembl:ENSMUSG00000075222|Vega:OTTMUSG00000013482 +258167 Olfr1182 MGI:MGI:3031370|Ensembl:ENSMUSG00000090097|Vega:OTTMUSG00000013980 +258168 Olfr566 MGI:MGI:3030400|Ensembl:ENSMUSG00000060888|Vega:OTTMUSG00000060061 +258169 Olfr625-ps1 MGI:MGI:3030459 +258170 Olfr590-ps1 MGI:MGI:3030424 +258172 Olfr674-ps1 MGI:MGI:3030508 +258173 Olfr1532-ps1 MGI:MGI:3031366|Ensembl:ENSMUSG00000073899|Vega:OTTMUSG00000059724 +258175 Olfr595-ps1 MGI:MGI:3030429 +258177 Olfr1222 MGI:MGI:3031056|Ensembl:ENSMUSG00000075101|Vega:OTTMUSG00000014019 +258178 Olfr180 MGI:MGI:3030014|Ensembl:ENSMUSG00000090629|Vega:OTTMUSG00000058833 +258180 Olfr699 MGI:MGI:3030533|Ensembl:ENSMUSG00000096714|Vega:OTTMUSG00000059680 +258181 Olfr406 MGI:MGI:3030240|Ensembl:ENSMUSG00000070375|Vega:OTTMUSG00000006172 +258182 Olfr388-ps1 MGI:MGI:3030222 +258183 Olfr917 MGI:MGI:3030751|Ensembl:ENSMUSG00000063225|Vega:OTTMUSG00000062194 +258184 Olfr839-ps1 MGI:MGI:3030673 +258185 Olfr255 MGI:MGI:3030089 +258186 Olfr75-ps1 MGI:MGI:2153204 +258187 Olfr682-ps1 MGI:MGI:3030516 +258189 Olfr624 MGI:MGI:3030458|Ensembl:ENSMUSG00000045780|Vega:OTTMUSG00000019052 +258192 Olfr1468-ps1 MGI:MGI:3031302 +258193 Olfr1397-ps1 MGI:MGI:3031231 +258194 Olfr949-ps1 MGI:MGI:3030783 +258196 Olfr309 MGI:MGI:3030143|Ensembl:ENSMUSG00000054054|Vega:OTTMUSG00000037759 +258198 Olfr224 MGI:MGI:3030058|Ensembl:ENSMUSG00000059279|Vega:OTTMUSG00000005750 +258199 Olfr1300-ps1 MGI:MGI:3031134|Ensembl:ENSMUSG00000109389|Vega:OTTMUSG00000015085 +258200 Olfr537-ps1 MGI:MGI:3030371 +258201 Olfr538 MGI:MGI:3030372|Ensembl:ENSMUSG00000095901|Vega:OTTMUSG00000060482 +258202 Olfr1376-ps1 MGI:MGI:3031210 +258203 Olfr1178 MGI:MGI:3031012|Ensembl:ENSMUSG00000056995|Vega:OTTMUSG00000013982 +258204 Olfr1267-ps1 MGI:MGI:3031101 +258206 Olfr1264 MGI:MGI:3031098|Ensembl:ENSMUSG00000075069|Vega:OTTMUSG00000014235 +258207 Olfr452 MGI:MGI:3030286|Ensembl:ENSMUSG00000094192|Vega:OTTMUSG00000042481 +258208 Olfr396-ps1 MGI:MGI:3030230 +258209 Olfr22-ps1 MGI:MGI:109313 +258210 Olfr387-ps1 MGI:MGI:3030221 +258211 Olfr383-ps1 MGI:MGI:3030217 +258212 Olfr650-ps1 MGI:MGI:3030484 +258213 Olfr580-ps1 MGI:MGI:3030414 +258214 Olfr1329 MGI:MGI:3031163|Ensembl:ENSMUSG00000096705|Vega:OTTMUSG00000008765 +258215 Olfr506 MGI:MGI:3030340|Ensembl:ENSMUSG00000058244|Vega:OTTMUSG00000060081 +258216 Olfr1034 MGI:MGI:3030868|Ensembl:ENSMUSG00000102091|Vega:OTTMUSG00000013601 +258217 Olfr1498-ps1 MGI:MGI:3031332 +258218 Olfr102 MGI:MGI:2177485|Ensembl:ENSMUSG00000091531|Vega:OTTMUSG00000037417 +258219 Olfr94 MGI:MGI:2177477|Ensembl:ENSMUSG00000043827 +258220 Olfr1148 MGI:MGI:3030982|Ensembl:ENSMUSG00000061875|Vega:OTTMUSG00000013879 +258222 Olfr310 MGI:MGI:3030144|Ensembl:ENSMUSG00000057540|Vega:OTTMUSG00000037757 +258224 Olfr1358 MGI:MGI:3031192 +258225 Olfr913 MGI:MGI:3030747|Ensembl:ENSMUSG00000059189|Vega:OTTMUSG00000062188 +258226 Olfr377-ps1 MGI:MGI:3030211 +258227 Olfr1418 MGI:MGI:3031252|Ensembl:ENSMUSG00000060556|Vega:OTTMUSG00000059430 +258228 Olfr1415 MGI:MGI:3031249|Ensembl:ENSMUSG00000057464|Vega:OTTMUSG00000048561 +258229 Olfr548-ps1 MGI:MGI:3030382 +258230 Olfr573-ps1 MGI:MGI:3030407 +258231 Olfr1471 MGI:MGI:3031305|Ensembl:ENSMUSG00000096320|Vega:OTTMUSG00000059508 +258232 Olfr774 MGI:MGI:3030608|Ensembl:ENSMUSG00000096229|Vega:OTTMUSG00000056555 +258233 Olfr741 MGI:MGI:3030575|Ensembl:ENSMUSG00000095765|Vega:OTTMUSG00000058483 +258235 Olfr1084 MGI:MGI:3030918|Ensembl:ENSMUSG00000110804|Vega:OTTMUSG00000013675 +258236 Olfr391-ps MGI:MGI:3030225|Ensembl:ENSMUSG00000070382|Vega:OTTMUSG00000006150 +258238 Olfr417 MGI:MGI:3030251|Ensembl:ENSMUSG00000066672|Vega:OTTMUSG00000050219 +258241 Olfr1212 MGI:MGI:3031046|Ensembl:ENSMUSG00000048226|Vega:OTTMUSG00000014052 +258242 Olfr955 MGI:MGI:3030789|Ensembl:ENSMUSG00000063176|Vega:OTTMUSG00000062346 +258244 Olfr1004-ps1 MGI:MGI:3030838 +258245 Olfr1036 MGI:MGI:3030870|Ensembl:ENSMUSG00000099820|Vega:OTTMUSG00000013625 +258246 Olfr594 MGI:MGI:3030428|Ensembl:ENSMUSG00000073954|Vega:OTTMUSG00000019085 +258247 Olfr645 MGI:MGI:3030479|Ensembl:ENSMUSG00000051340|Vega:OTTMUSG00000019076 +258248 Olfr576 MGI:MGI:3030410|Ensembl:ENSMUSG00000073962|Vega:OTTMUSG00000047706 +258249 Olfr845 MGI:MGI:3030679|Ensembl:ENSMUSG00000061614|Vega:OTTMUSG00000061258 +258252 Olfr813 MGI:MGI:3030647|Ensembl:ENSMUSG00000052818|Vega:OTTMUSG00000056630 +258254 Olfr1516-ps MGI:MGI:3031350 +258255 Olfr1010 MGI:MGI:3030844|Ensembl:ENSMUSG00000110879|Vega:OTTMUSG00000013555 +258257 Olfr1313 MGI:MGI:3031147|Ensembl:ENSMUSG00000074946|Vega:OTTMUSG00000015106 +258258 Olfr1308 MGI:MGI:3031142|Ensembl:ENSMUSG00000074952|Vega:OTTMUSG00000015110 +258259 Olfr1338 MGI:MGI:3031172|Ensembl:ENSMUSG00000095218|Vega:OTTMUSG00000008743 +258261 Olfr325 MGI:MGI:3030159|Ensembl:ENSMUSG00000060765|Vega:OTTMUSG00000005751 +258263 Olfr117 MGI:MGI:2177500|Ensembl:ENSMUSG00000095286|Vega:OTTMUSG00000037466 +258264 Olfr747 MGI:MGI:3030581|Ensembl:ENSMUSG00000057179|Vega:OTTMUSG00000058490 +258265 Olfr1333 MGI:MGI:3031167|Ensembl:ENSMUSG00000110947|Vega:OTTMUSG00000008764 +258266 Olfr247 MGI:MGI:3030081|Ensembl:ENSMUSG00000095608|Vega:OTTMUSG00000056649 +258267 Olfr370 MGI:MGI:3030204|Ensembl:ENSMUSG00000047286|Vega:OTTMUSG00000061135 +258268 Olfr1511 MGI:MGI:3031345|Ensembl:ENSMUSG00000063867|Vega:OTTMUSG00000053560 +258269 Olfr930 MGI:MGI:3030764|Ensembl:ENSMUSG00000063221|Vega:OTTMUSG00000062240 +258270 Olfr448 MGI:MGI:3030282|Ensembl:ENSMUSG00000043119|Vega:OTTMUSG00000057459 +258271 Olfr1311 MGI:MGI:3031145|Ensembl:ENSMUSG00000109403|Vega:OTTMUSG00000015119 +258272 Olfr1402 MGI:MGI:3031236|Ensembl:ENSMUSG00000051392|Vega:OTTMUSG00000053232 +258273 Olfr1394 MGI:MGI:3031228|Ensembl:ENSMUSG00000048378|Vega:OTTMUSG00000005542 +258274 Olfr1412 MGI:MGI:3031246|Ensembl:ENSMUSG00000046300|Vega:OTTMUSG00000048566 +258275 Olfr729 MGI:MGI:3030563|Ensembl:ENSMUSG00000049011|Vega:OTTMUSG00000058471 +258276 Olfr960 MGI:MGI:3030794|Ensembl:ENSMUSG00000059867|Vega:OTTMUSG00000062353 +258277 Olfr281 MGI:MGI:3030115|Ensembl:ENSMUSG00000032987|Vega:OTTMUSG00000058682 +258278 Olfr284 MGI:MGI:3030118|Ensembl:ENSMUSG00000051793|Vega:OTTMUSG00000058679 +258279 Olfr846 MGI:MGI:3030680|Ensembl:ENSMUSG00000058692|Vega:OTTMUSG00000061259 +258280 Olfr1366 MGI:MGI:3031200|Ensembl:ENSMUSG00000048996|Vega:OTTMUSG00000058291 +258281 Olfr780 MGI:MGI:3030614|Ensembl:ENSMUSG00000049573|Vega:OTTMUSG00000056561 +258282 Olfr801 MGI:MGI:3030635|Ensembl:ENSMUSG00000058513|Vega:OTTMUSG00000056618 +258283 Olfr981 MGI:MGI:3030815|Ensembl:ENSMUSG00000046678|Vega:OTTMUSG00000062408 +258284 Olfr114 MGI:MGI:2177497|Ensembl:ENSMUSG00000062629|Vega:OTTMUSG00000037463 +258285 Olfr122 MGI:MGI:2177505|Ensembl:ENSMUSG00000083947|Vega:OTTMUSG00000037473 +258286 Olfr113 MGI:MGI:2177496|Ensembl:ENSMUSG00000092292|Vega:OTTMUSG00000037462 +258287 Olfr125 MGI:MGI:2177508|Ensembl:ENSMUSG00000050613|Vega:OTTMUSG00000037476 +258288 Olfr1484 MGI:MGI:3031318|Ensembl:ENSMUSG00000096289|Vega:OTTMUSG00000059534 +258289 Olfr1324 MGI:MGI:3031158|Ensembl:ENSMUSG00000048173|Vega:OTTMUSG00000017474 +258290 Olfr1143 MGI:MGI:3030977|Ensembl:ENSMUSG00000068815|Vega:OTTMUSG00000013844 +258291 Olfr1167 MGI:MGI:3031001|Ensembl:ENSMUSG00000100899|Vega:OTTMUSG00000013947 +258292 Olfr446 MGI:MGI:3030280|Ensembl:ENSMUSG00000073111|Vega:OTTMUSG00000057461 +258293 Olfr437 MGI:MGI:3030271|Ensembl:ENSMUSG00000071481|Vega:OTTMUSG00000057729 +258294 Olfr1115 MGI:MGI:3030949|Ensembl:ENSMUSG00000070856|Vega:OTTMUSG00000013776 +258295 Olfr746 MGI:MGI:3030580|Ensembl:ENSMUSG00000058188|Vega:OTTMUSG00000058489 +258296 Olfr745 MGI:MGI:3030579|Ensembl:ENSMUSG00000050028|Vega:OTTMUSG00000058487 +258297 Olfr827 MGI:MGI:3030661|Ensembl:ENSMUSG00000045559|Vega:OTTMUSG00000056692 +258298 Olfr1475 MGI:MGI:3031309|Ensembl:ENSMUSG00000096708|Vega:OTTMUSG00000059525 +258299 Olfr1461 MGI:MGI:3031295|Ensembl:ENSMUSG00000045883|Vega:OTTMUSG00000059497 +258300 Olfr1449 MGI:MGI:3031283|Ensembl:ENSMUSG00000049498|Vega:OTTMUSG00000059460 +258301 Olfr1340 MGI:MGI:3031174|Ensembl:ENSMUSG00000070821 +258302 Olfr420 MGI:MGI:3030254|Ensembl:ENSMUSG00000055033|Vega:OTTMUSG00000050217 +258303 Olfr518 MGI:MGI:3030352|Ensembl:ENSMUSG00000046431|Vega:OTTMUSG00000060095 +258304 Olfr498 MGI:MGI:3030332|Ensembl:ENSMUSG00000096679|Vega:OTTMUSG00000059985 +258305 Olfr1356 MGI:MGI:3031190|Ensembl:ENSMUSG00000051190|Vega:OTTMUSG00000056724 +258306 Olfr1337 MGI:MGI:3031171|Ensembl:ENSMUSG00000111159|Vega:OTTMUSG00000008748 +258307 Olfr493 MGI:MGI:3030327|Ensembl:ENSMUSG00000093980|Vega:OTTMUSG00000059980 +258308 Olfr510 MGI:MGI:3030344|Ensembl:ENSMUSG00000096209|Vega:OTTMUSG00000060085 +258309 Olfr657 MGI:MGI:3030491|Ensembl:ENSMUSG00000073923|Vega:OTTMUSG00000019180 +258310 Olfr145 MGI:MGI:2177528|Ensembl:ENSMUSG00000066748|Vega:OTTMUSG00000061757 +258311 Olfr601 MGI:MGI:3030435|Ensembl:ENSMUSG00000109951|Vega:OTTMUSG00000019029 +258313 Olfr726 MGI:MGI:3030560|Ensembl:ENSMUSG00000060523|Vega:OTTMUSG00000058467 +258314 Olfr725 MGI:MGI:3030559|Ensembl:ENSMUSG00000068437|Vega:OTTMUSG00000058466 +258315 Olfr767 MGI:MGI:3030601|Ensembl:ENSMUSG00000059762|Vega:OTTMUSG00000056480 +258316 Olfr727 MGI:MGI:3030561|Ensembl:ENSMUSG00000059488|Vega:OTTMUSG00000058469 +258317 Olfr1145 MGI:MGI:3030979|Ensembl:ENSMUSG00000068814|Vega:OTTMUSG00000013869 +258318 Olfr186 MGI:MGI:3030020|Ensembl:ENSMUSG00000047960|Vega:OTTMUSG00000058839 +258319 Olfr187 MGI:MGI:3030021|Ensembl:ENSMUSG00000043357|Vega:OTTMUSG00000058840 +258320 Olfr1232 MGI:MGI:3031066|Ensembl:ENSMUSG00000075092|Vega:OTTMUSG00000014159 +258321 Olfr809 MGI:MGI:3030643|Ensembl:ENSMUSG00000050251|Vega:OTTMUSG00000056626 +258322 Olfr554 MGI:MGI:3030388|Ensembl:ENSMUSG00000073971|Vega:OTTMUSG00000060021 +258323 Olfr943 MGI:MGI:3030777|Ensembl:ENSMUSG00000094970|Vega:OTTMUSG00000062277 +258324 Olfr129 MGI:MGI:2177512|Ensembl:ENSMUSG00000081724|Vega:OTTMUSG00000037351 +258325 Olfr110 MGI:MGI:2177493|Ensembl:ENSMUSG00000090894|Vega:OTTMUSG00000037433 +258326 Olfr642 MGI:MGI:3030476|Ensembl:ENSMUSG00000049797|Vega:OTTMUSG00000019099 +258327 Olfr958 MGI:MGI:3030792|Ensembl:ENSMUSG00000050853|Vega:OTTMUSG00000062350 +258328 Olfr954 MGI:MGI:3030788|Ensembl:ENSMUSG00000094745|Vega:OTTMUSG00000062345 +258329 Olfr135 MGI:MGI:2177518|Ensembl:ENSMUSG00000057801|Vega:OTTMUSG00000037361 +258330 Olfr1274-ps MGI:MGI:3031108|Ensembl:ENSMUSG00000082980|Vega:OTTMUSG00000014276 +258331 Olfr1330 MGI:MGI:3031164|Ensembl:ENSMUSG00000073768|Vega:OTTMUSG00000008767 +258333 Olfr893 MGI:MGI:3030727|Ensembl:ENSMUSG00000093901|Vega:OTTMUSG00000061819 +258334 Olfr1396 MGI:MGI:3031230|Ensembl:ENSMUSG00000047511|Vega:OTTMUSG00000005535 +258335 Olfr374 MGI:MGI:3030208|Ensembl:ENSMUSG00000046881|Vega:OTTMUSG00000061132 +258336 Olfr77 MGI:MGI:2153206|Ensembl:ENSMUSG00000051118|Vega:OTTMUSG00000061700 +258338 Olfr1259 MGI:MGI:3031093|Ensembl:ENSMUSG00000068806|Vega:OTTMUSG00000014218 +258339 Olfr1269 MGI:MGI:3031103|Ensembl:ENSMUSG00000084336|Vega:OTTMUSG00000014223 +258340 Olfr1265 MGI:MGI:3031099|Ensembl:ENSMUSG00000059910|Vega:OTTMUSG00000014240 +258341 Olfr1495 MGI:MGI:3031329|Ensembl:ENSMUSG00000047207|Vega:OTTMUSG00000059632 +258342 Olfr1491 MGI:MGI:3031325|Ensembl:ENSMUSG00000051156|Vega:OTTMUSG00000059541 +258343 Olfr397 MGI:MGI:3030231|Ensembl:ENSMUSG00000057050|Vega:OTTMUSG00000006159 +258344 Olfr390 MGI:MGI:3030224|Ensembl:ENSMUSG00000069818|Vega:OTTMUSG00000006149 +258345 Olfr1121 MGI:MGI:3030955|Ensembl:ENSMUSG00000070852|Vega:OTTMUSG00000013775 +258346 Olfr1128 MGI:MGI:3030962|Ensembl:ENSMUSG00000075156|Vega:OTTMUSG00000013839 +258347 Olfr1123 MGI:MGI:3030957|Ensembl:ENSMUSG00000043274 +258348 Olfr1133 MGI:MGI:3030967|Ensembl:ENSMUSG00000075155|Vega:OTTMUSG00000013842 +258350 Olfr706 MGI:MGI:3030540|Ensembl:ENSMUSG00000109354|Vega:OTTMUSG00000059722 +258351 Olfr633 MGI:MGI:3030467|Ensembl:ENSMUSG00000073937|Vega:OTTMUSG00000019035 +258352 Olfr692 MGI:MGI:3030526|Ensembl:ENSMUSG00000073906|Vega:OTTMUSG00000060487 +258353 Olfr521 MGI:MGI:3030355|Ensembl:ENSMUSG00000073997|Vega:OTTMUSG00000059049 +258354 Olfr168 MGI:MGI:3030002|Ensembl:ENSMUSG00000061361|Vega:OTTMUSG00000058695 +258355 Olfr677 MGI:MGI:3030511|Ensembl:ENSMUSG00000073914|Vega:OTTMUSG00000060557 +258356 Olfr564 MGI:MGI:3030398|Ensembl:ENSMUSG00000048469|Vega:OTTMUSG00000060059 +258357 Olfr574 MGI:MGI:3030408|Ensembl:ENSMUSG00000045824|Vega:OTTMUSG00000060109 +258358 Olfr557 MGI:MGI:3030391|Ensembl:ENSMUSG00000073967|Vega:OTTMUSG00000060024 +258359 Olfr1312 MGI:MGI:3031146|Ensembl:ENSMUSG00000074947|Vega:OTTMUSG00000015104 +258360 Olfr731 MGI:MGI:3030565|Ensembl:ENSMUSG00000048080|Vega:OTTMUSG00000058473 +258361 Olfr495 MGI:MGI:3030329|Ensembl:ENSMUSG00000110253|Vega:OTTMUSG00000059982 +258362 Olfr1094 MGI:MGI:3030928|Ensembl:ENSMUSG00000044213|Vega:OTTMUSG00000013702 +258363 Olfr1093 MGI:MGI:3030927|Ensembl:ENSMUSG00000047969|Vega:OTTMUSG00000013699 +258364 Olfr976 MGI:MGI:3030810|Ensembl:ENSMUSG00000047352|Vega:OTTMUSG00000062403 +258365 Olfr361 MGI:MGI:3030195|Ensembl:ENSMUSG00000075378|Vega:OTTMUSG00000012202 +258366 Olfr434 MGI:MGI:3030268|Ensembl:ENSMUSG00000059411|Vega:OTTMUSG00000057772 +258368 Olfr1450 MGI:MGI:3031284|Ensembl:ENSMUSG00000062892|Vega:OTTMUSG00000059461 +258369 Olfr509 MGI:MGI:3030343|Ensembl:ENSMUSG00000049280|Vega:OTTMUSG00000060084 +258370 Olfr1253 MGI:MGI:3031393|Ensembl:ENSMUSG00000075075|Vega:OTTMUSG00000014168 +258371 Olfr368 MGI:MGI:3030202|Ensembl:ENSMUSG00000049018|Vega:OTTMUSG00000012653 +258372 Olfr918 MGI:MGI:3030752|Ensembl:ENSMUSG00000046150|Vega:OTTMUSG00000062196 +258373 Olfr323 MGI:MGI:3030157|Ensembl:ENSMUSG00000043880|Vega:OTTMUSG00000005753 +258374 Olfr127 MGI:MGI:2177510|Ensembl:ENSMUSG00000058114|Vega:OTTMUSG00000037339 +258375 Olfr794 MGI:MGI:3030628|Ensembl:ENSMUSG00000044293|Vega:OTTMUSG00000056575 +258377 Olfr654 MGI:MGI:3030488|Ensembl:ENSMUSG00000073925|Vega:OTTMUSG00000019184 +258378 Olfr593 MGI:MGI:3030427|Ensembl:ENSMUSG00000073955|Vega:OTTMUSG00000019019 +258379 Olfr1284 MGI:MGI:3031118|Ensembl:ENSMUSG00000108931|Vega:OTTMUSG00000015072 +258380 Olfr461 MGI:MGI:3030295|Ensembl:ENSMUSG00000068259|Vega:OTTMUSG00000056379 +258381 Olfr460 MGI:MGI:3030294|Ensembl:ENSMUSG00000045514|Vega:OTTMUSG00000039754 +258382 Olfr208 MGI:MGI:3030042 +258383 Olfr1347 MGI:MGI:3031181|Ensembl:ENSMUSG00000034583|Vega:OTTMUSG00000060115 +258384 Olfr1350 MGI:MGI:3031184|Ensembl:ENSMUSG00000056696|Vega:OTTMUSG00000060118 +258385 Olfr1323 MGI:MGI:3031157|Ensembl:ENSMUSG00000050504|Vega:OTTMUSG00000017797 +258386 Olfr1058 MGI:MGI:3030892|Ensembl:ENSMUSG00000075186|Vega:OTTMUSG00000013565 +258387 Olfr720 MGI:MGI:3030554|Ensembl:ENSMUSG00000052417|Vega:OTTMUSG00000058428 +258388 Olfr1279 MGI:MGI:3031113|Ensembl:ENSMUSG00000109813|Vega:OTTMUSG00000015191 +258389 Olfr1278 MGI:MGI:3031112|Ensembl:ENSMUSG00000068647|Vega:OTTMUSG00000015194 +258390 Olfr1276 MGI:MGI:3031110|Ensembl:ENSMUSG00000063844|Vega:OTTMUSG00000015187 +258391 Olfr1277 MGI:MGI:3031111|Ensembl:ENSMUSG00000074965|Vega:OTTMUSG00000015192 +258392 Olfr190 MGI:MGI:3030024|Ensembl:ENSMUSG00000064006|Vega:OTTMUSG00000058843 +258393 Olfr1325 MGI:MGI:3031159|Ensembl:ENSMUSG00000051706|Vega:OTTMUSG00000020739 +258394 Olfr1328 MGI:MGI:3031162|Ensembl:ENSMUSG00000111259|Vega:OTTMUSG00000008771 +258395 Olfr1288 MGI:MGI:3031122|Ensembl:ENSMUSG00000044039|Vega:OTTMUSG00000015078 +258396 Olfr1305 MGI:MGI:3031139|Ensembl:ENSMUSG00000074955|Vega:OTTMUSG00000015081 +258397 Olfr1303 MGI:MGI:3031137|Ensembl:ENSMUSG00000093804|Vega:OTTMUSG00000015086 +258398 Olfr1295 MGI:MGI:3031129|Ensembl:ENSMUSG00000108919|Vega:OTTMUSG00000015082 +258399 Olfr1289 MGI:MGI:3031123|Ensembl:ENSMUSG00000061195|Vega:OTTMUSG00000015071 +258400 Olfr228 MGI:MGI:3030062|Ensembl:ENSMUSG00000111772|Vega:OTTMUSG00000013617 +258401 Olfr1076 MGI:MGI:3030910|Ensembl:ENSMUSG00000060742|Vega:OTTMUSG00000013612 +258402 Olfr1079 MGI:MGI:3030913|Ensembl:ENSMUSG00000075179|Vega:OTTMUSG00000013636 +258403 Olfr1065 MGI:MGI:3030899|Ensembl:ENSMUSG00000111306|Vega:OTTMUSG00000013616 +258404 Olfr1080 MGI:MGI:3030914|Ensembl:ENSMUSG00000110912|Vega:OTTMUSG00000013634 +258405 Olfr1420 MGI:MGI:3031254|Ensembl:ENSMUSG00000060878|Vega:OTTMUSG00000059432 +258406 Olfr462 MGI:MGI:3030296|Ensembl:ENSMUSG00000093839|Vega:OTTMUSG00000001431 +258407 Olfr464 MGI:MGI:3030298|Ensembl:ENSMUSG00000060787|Vega:OTTMUSG00000001433 +258408 Olfr463 MGI:MGI:3030297|Ensembl:ENSMUSG00000093920|Vega:OTTMUSG00000001432 +258409 Olfr1431 MGI:MGI:3031265|Ensembl:ENSMUSG00000094133|Vega:OTTMUSG00000042677 +258410 Olfr291 MGI:MGI:3030125|Ensembl:ENSMUSG00000070460|Vega:OTTMUSG00000037864 +258411 Olfr290 MGI:MGI:3030124|Ensembl:ENSMUSG00000070459|Vega:OTTMUSG00000037866 +258412 Olfr877 MGI:MGI:3030711|Ensembl:ENSMUSG00000066749|Vega:OTTMUSG00000061756 +258413 Olfr881 MGI:MGI:3030715|Ensembl:ENSMUSG00000060583|Vega:OTTMUSG00000061809 +258414 Olfr883 MGI:MGI:3030717|Ensembl:ENSMUSG00000094461|Vega:OTTMUSG00000061770 +258415 Olfr887 MGI:MGI:3030721|Ensembl:ENSMUSG00000096167|Vega:OTTMUSG00000061812 +258416 Olfr888 MGI:MGI:3030722|Ensembl:ENSMUSG00000095527|Vega:OTTMUSG00000061813 +258417 Olfr470 MGI:MGI:3030304|Ensembl:ENSMUSG00000109542|Vega:OTTMUSG00000059951 +258418 Olfr469 MGI:MGI:3030303|Ensembl:ENSMUSG00000095910|Vega:OTTMUSG00000059949 +258419 Olfr465-ps1 MGI:MGI:3030299 +258420 Olfr221 MGI:MGI:3030055|Ensembl:ENSMUSG00000044286|Vega:OTTMUSG00000058604 +258421 Olfr223 MGI:MGI:3030057|Ensembl:ENSMUSG00000048919|Vega:OTTMUSG00000005792 +258422 Olfr742 MGI:MGI:3030576|Ensembl:ENSMUSG00000068431|Vega:OTTMUSG00000058484 +258423 Olfr1510 MGI:MGI:3031344|Ensembl:ENSMUSG00000063106|Vega:OTTMUSG00000053561 +258424 Olfr1512 MGI:MGI:3031346|Ensembl:ENSMUSG00000094140|Vega:OTTMUSG00000053559 +258425 Olfr994 MGI:MGI:3030828|Ensembl:ENSMUSG00000075219|Vega:OTTMUSG00000013477 +258426 Olfr995 MGI:MGI:3030829|Ensembl:ENSMUSG00000075218|Vega:OTTMUSG00000013480 +258427 Olfr993 MGI:MGI:3030827|Ensembl:ENSMUSG00000075220|Vega:OTTMUSG00000013484 +258428 Olfr998 MGI:MGI:3030832|Ensembl:ENSMUSG00000111454|Vega:OTTMUSG00000013507 +258429 Olfr996 MGI:MGI:3030830|Ensembl:ENSMUSG00000111179|Vega:OTTMUSG00000013503 +258430 Olfr938 MGI:MGI:3030772|Ensembl:ENSMUSG00000048501|Vega:OTTMUSG00000062260 +258431 Olfr937 MGI:MGI:3030771|Ensembl:ENSMUSG00000094182|Vega:OTTMUSG00000062258 +258432 Olfr919 MGI:MGI:3030753|Ensembl:ENSMUSG00000056961|Vega:OTTMUSG00000062198 +258433 Olfr933 MGI:MGI:3030767|Ensembl:ENSMUSG00000058515|Vega:OTTMUSG00000062244 +258434 Olfr934 MGI:MGI:3030768|Ensembl:ENSMUSG00000057424|Vega:OTTMUSG00000062245 +258435 Olfr382 MGI:MGI:3030216|Ensembl:ENSMUSG00000095312|Vega:OTTMUSG00000006139 +258436 Olfr458 MGI:MGI:3030292|Ensembl:ENSMUSG00000068574|Vega:OTTMUSG00000057381 +258437 Olfr450 MGI:MGI:3030284|Ensembl:ENSMUSG00000054431|Vega:OTTMUSG00000057457 +258438 Olfr215 MGI:MGI:3030049|Ensembl:ENSMUSG00000050654|Vega:OTTMUSG00000057306 +258439 Olfr1309 MGI:MGI:3031143|Ensembl:ENSMUSG00000109528|Vega:OTTMUSG00000015107 +258440 Olfr1317 MGI:MGI:3031151|Ensembl:ENSMUSG00000050776|Vega:OTTMUSG00000015116 +258441 Olfr1310 MGI:MGI:3031144|Ensembl:ENSMUSG00000108827|Vega:OTTMUSG00000015108 +258442 Olfr1314 MGI:MGI:3031148|Ensembl:ENSMUSG00000074945|Vega:OTTMUSG00000015103 +258443 Olfr164 MGI:MGI:3029998|Ensembl:ENSMUSG00000050742|Vega:OTTMUSG00000053541 +258444 Olfr694 MGI:MGI:3030528|Ensembl:ENSMUSG00000064223|Vega:OTTMUSG00000059675 +258445 Olfr693 MGI:MGI:3030527|Ensembl:ENSMUSG00000051680|Vega:OTTMUSG00000059674 +258446 Olfr1231 MGI:MGI:3031065|Ensembl:ENSMUSG00000075093|Vega:OTTMUSG00000014015 +258447 Olfr1241 MGI:MGI:3031075|Ensembl:ENSMUSG00000075086|Vega:OTTMUSG00000014154 +258448 Olfr92 MGI:MGI:2177475|Ensembl:ENSMUSG00000096477|Vega:OTTMUSG00000037322 +258449 Olfr282 MGI:MGI:3030116|Ensembl:ENSMUSG00000063780 +258450 Olfr1199 MGI:MGI:3031033|Ensembl:ENSMUSG00000089892|Vega:OTTMUSG00000014003 +258451 Olfr1215 MGI:MGI:3031049|Ensembl:ENSMUSG00000100016|Vega:OTTMUSG00000014039 +258453 Olfr1209 MGI:MGI:3031043|Ensembl:ENSMUSG00000075113|Vega:OTTMUSG00000014051 +258454 Olfr1202 MGI:MGI:3031036|Ensembl:ENSMUSG00000064084|Vega:OTTMUSG00000014050 +258455 Olfr1204 MGI:MGI:3031038|Ensembl:ENSMUSG00000061798|Vega:OTTMUSG00000014048 +258456 Olfr1196 MGI:MGI:3031030|Ensembl:ENSMUSG00000075120|Vega:OTTMUSG00000013995 +258457 Olfr108 MGI:MGI:2177491|Ensembl:ENSMUSG00000059687|Vega:OTTMUSG00000037429 +258458 Olfr165 MGI:MGI:3029999|Ensembl:ENSMUSG00000050158|Vega:OTTMUSG00000058692 +258459 Olfr1388 MGI:MGI:3031222|Ensembl:ENSMUSG00000047702|Vega:OTTMUSG00000005552 +258460 Olfr1391 MGI:MGI:3031225|Ensembl:ENSMUSG00000101874|Vega:OTTMUSG00000005547 +258461 Olfr1381 MGI:MGI:3031215|Ensembl:ENSMUSG00000095187|Vega:OTTMUSG00000005559 +258462 Olfr1392 MGI:MGI:3031226|Ensembl:ENSMUSG00000101750|Vega:OTTMUSG00000005545 +258463 Olfr1393 MGI:MGI:3031227|Ensembl:ENSMUSG00000059864|Vega:OTTMUSG00000005544 +258464 Olfr1384 MGI:MGI:3031218|Ensembl:ENSMUSG00000044170|Vega:OTTMUSG00000005556 +258465 Olfr1387 MGI:MGI:3031221|Ensembl:ENSMUSG00000063386|Vega:OTTMUSG00000005561 +258466 Olfr1261 MGI:MGI:3031095|Ensembl:ENSMUSG00000061295 +258468 Olfr1254 MGI:MGI:3031088|Ensembl:ENSMUSG00000075074|Vega:OTTMUSG00000014230 +258469 Olfr90 MGI:MGI:2177473|Ensembl:ENSMUSG00000056600|Vega:OTTMUSG00000037320 +258470 Olfr91 MGI:MGI:2177474|Ensembl:ENSMUSG00000095377|Vega:OTTMUSG00000037321 +258471 Olfr891 MGI:MGI:3030725|Ensembl:ENSMUSG00000045528|Vega:OTTMUSG00000061817 +258472 Olfr899 MGI:MGI:3030733 +258473 Olfr897-ps1 MGI:MGI:3030731 +258474 Olfr890 MGI:MGI:3030724|Ensembl:ENSMUSG00000096409|Vega:OTTMUSG00000061815 +258475 Olfr889 MGI:MGI:3030723|Ensembl:ENSMUSG00000096356|Vega:OTTMUSG00000061814 +258477 Olfr197 MGI:MGI:3030031|Ensembl:ENSMUSG00000109020|Vega:OTTMUSG00000059125 +258478 Olfr183 MGI:MGI:3030017|Ensembl:ENSMUSG00000062105|Vega:OTTMUSG00000058836 +258479 Olfr203 MGI:MGI:3030037|Ensembl:ENSMUSG00000068182|Vega:OTTMUSG00000055629 +258480 Olfr130 MGI:MGI:2177513|Ensembl:ENSMUSG00000094878|Vega:OTTMUSG00000037353 +258481 Olfr137 MGI:MGI:2177520|Ensembl:ENSMUSG00000054940|Vega:OTTMUSG00000037363 +258482 Olfr266 MGI:MGI:3030100|Ensembl:ENSMUSG00000043529|Vega:OTTMUSG00000052104 +258483 Olfr1411 MGI:MGI:3031245|Ensembl:ENSMUSG00000062497|Vega:OTTMUSG00000048567 +258484 Olfr1410 MGI:MGI:3031244|Ensembl:ENSMUSG00000063583|Vega:OTTMUSG00000048568 +258485 Olfr724 MGI:MGI:3030558|Ensembl:ENSMUSG00000096254|Vega:OTTMUSG00000058465 +258486 Olfr730 MGI:MGI:3030564|Ensembl:ENSMUSG00000109835|Vega:OTTMUSG00000058472 +258487 Olfr722 MGI:MGI:3030556|Ensembl:ENSMUSG00000048933|Vega:OTTMUSG00000058463 +258488 Olfr474 MGI:MGI:3030308|Ensembl:ENSMUSG00000094197|Vega:OTTMUSG00000059955 +258489 Olfr486 MGI:MGI:3030320|Ensembl:ENSMUSG00000096068|Vega:OTTMUSG00000059969 +258490 Olfr492 MGI:MGI:3030326|Ensembl:ENSMUSG00000109497|Vega:OTTMUSG00000059979 +258491 Olfr490 MGI:MGI:3030324|Ensembl:ENSMUSG00000109884|Vega:OTTMUSG00000059976 +258492 Olfr484 MGI:MGI:3030318|Ensembl:ENSMUSG00000110171|Vega:OTTMUSG00000059967 +258493 Olfr319 MGI:MGI:3030153|Ensembl:ENSMUSG00000064044|Vega:OTTMUSG00000005757 +258494 Olfr318 MGI:MGI:3030152|Ensembl:ENSMUSG00000108265|Vega:OTTMUSG00000005746 +258495 Olfr328 MGI:MGI:3030162|Ensembl:ENSMUSG00000057654|Vega:OTTMUSG00000005749 +258497 Olfr961 MGI:MGI:3030795|Ensembl:ENSMUSG00000059106|Vega:OTTMUSG00000062383 +258498 Olfr148 MGI:MGI:2660713|Ensembl:ENSMUSG00000048299|Vega:OTTMUSG00000062352 +258499 Olfr945 MGI:MGI:3030779|Ensembl:ENSMUSG00000063380|Vega:OTTMUSG00000062281 +258500 Olfr944 MGI:MGI:3030778|Ensembl:ENSMUSG00000096555|Vega:OTTMUSG00000062279 +258501 Olfr959 MGI:MGI:3030793|Ensembl:ENSMUSG00000059366|Vega:OTTMUSG00000062351 +258502 Olfr279 MGI:MGI:3030113|Ensembl:ENSMUSG00000054036|Vega:OTTMUSG00000058684 +258503 Olfr98 MGI:MGI:2177481|Ensembl:ENSMUSG00000063660|Vega:OTTMUSG00000037376 +258504 Olfr107 MGI:MGI:2177490|Ensembl:ENSMUSG00000063188|Vega:OTTMUSG00000037425 +258505 Olfr97 MGI:MGI:2177480|Ensembl:ENSMUSG00000058802|Vega:OTTMUSG00000037334 +258506 Olfr95 MGI:MGI:2177478|Ensembl:ENSMUSG00000049561|Vega:OTTMUSG00000037332 +258507 Olfr96 MGI:MGI:2177479|Ensembl:ENSMUSG00000064121|Vega:OTTMUSG00000037333 +258508 Olfr99 MGI:MGI:2177482|Ensembl:ENSMUSG00000061972|Vega:OTTMUSG00000037414 +258509 Olfr1375 MGI:MGI:3031209|Ensembl:ENSMUSG00000057890|Vega:OTTMUSG00000005591 +258511 Olfr523 MGI:MGI:3030357|Ensembl:ENSMUSG00000051051|Vega:OTTMUSG00000060575 +258512 Olfr530 MGI:MGI:3030364|Ensembl:ENSMUSG00000060974|Vega:OTTMUSG00000060473 +258513 Olfr536 MGI:MGI:3030370|Ensembl:ENSMUSG00000052508|Vega:OTTMUSG00000060480 +258515 Olfr854 MGI:MGI:3030688|Ensembl:ENSMUSG00000095667|Vega:OTTMUSG00000061275 +258516 Olfr850 MGI:MGI:3030684|Ensembl:ENSMUSG00000094535|Vega:OTTMUSG00000061271 +258517 Olfr855 MGI:MGI:3030689|Ensembl:ENSMUSG00000043087|Vega:OTTMUSG00000061276 +258518 Olfr847 MGI:MGI:3030681|Ensembl:ENSMUSG00000059821|Vega:OTTMUSG00000061261 +258519 Olfr859 MGI:MGI:3030693|Ensembl:ENSMUSG00000095448|Vega:OTTMUSG00000061510 +258520 Olfr849 MGI:MGI:3030683|Ensembl:ENSMUSG00000052182|Vega:OTTMUSG00000061263 +258521 Olfr860 MGI:MGI:3030694|Ensembl:ENSMUSG00000066905|Vega:OTTMUSG00000061512 +258522 Olfr1183 MGI:MGI:3031017|Ensembl:ENSMUSG00000049372|Vega:OTTMUSG00000013989 +258523 Olfr1186 MGI:MGI:3031020|Ensembl:ENSMUSG00000082882|Vega:OTTMUSG00000013991 +258524 Olfr1168 MGI:MGI:3031002|Ensembl:ENSMUSG00000061342|Vega:OTTMUSG00000013941 +258525 Olfr1170 MGI:MGI:3031004|Ensembl:ENSMUSG00000075133|Vega:OTTMUSG00000013945 +258526 Olfr1367 MGI:MGI:3031201|Ensembl:ENSMUSG00000045508|Vega:OTTMUSG00000000418 +258527 Olfr1368 MGI:MGI:3031202|Ensembl:ENSMUSG00000045474|Vega:OTTMUSG00000058290 +258528 Olfr1370 MGI:MGI:3031204|Ensembl:ENSMUSG00000042869|Vega:OTTMUSG00000058287 +258529 Olfr313 MGI:MGI:3030147|Ensembl:ENSMUSG00000070438|Vega:OTTMUSG00000005763 +258530 Olfr311 MGI:MGI:3030145|Ensembl:ENSMUSG00000094805|Vega:OTTMUSG00000005766 +258531 Olfr315 MGI:MGI:3030149|Ensembl:ENSMUSG00000056959|Vega:OTTMUSG00000005761 +258532 Olfr373 MGI:MGI:3030207|Ensembl:ENSMUSG00000061561|Vega:OTTMUSG00000061131 +258533 Olfr1364 MGI:MGI:3031198|Ensembl:ENSMUSG00000046016|Vega:OTTMUSG00000000423 +258534 Olfr1361 MGI:MGI:3031195|Ensembl:ENSMUSG00000049737|Vega:OTTMUSG00000000441 +258536 Olfr1360 MGI:MGI:3031194|Ensembl:ENSMUSG00000108534|Vega:OTTMUSG00000000440 +258537 Olfr777 MGI:MGI:3030611|Ensembl:ENSMUSG00000062914|Vega:OTTMUSG00000056558 +258538 Olfr775 MGI:MGI:3030609|Ensembl:ENSMUSG00000096220|Vega:OTTMUSG00000056556 +258540 Olfr771 MGI:MGI:3030605|Ensembl:ENSMUSG00000061367|Vega:OTTMUSG00000056552 +258541 Olfr800 MGI:MGI:3030634|Ensembl:ENSMUSG00000108114|Vega:OTTMUSG00000056617 +258542 Olfr786 MGI:MGI:3030620|Ensembl:ENSMUSG00000095696|Vega:OTTMUSG00000056567 +258543 Olfr810 MGI:MGI:3030644|Ensembl:ENSMUSG00000069421|Vega:OTTMUSG00000056627 +258544 Olfr788 MGI:MGI:3030622|Ensembl:ENSMUSG00000049217|Vega:OTTMUSG00000056569 +258545 Olfr811 MGI:MGI:3030645|Ensembl:ENSMUSG00000063173|Vega:OTTMUSG00000056628 +258546 Olfr806 MGI:MGI:3030640|Ensembl:ENSMUSG00000071065|Vega:OTTMUSG00000056623 +258547 Olfr803 MGI:MGI:3030637|Ensembl:ENSMUSG00000046041|Vega:OTTMUSG00000056620 +258548 Olfr805 MGI:MGI:3030639|Ensembl:ENSMUSG00000096858|Vega:OTTMUSG00000056622 +258549 Olfr798 MGI:MGI:3030632|Ensembl:ENSMUSG00000095002|Vega:OTTMUSG00000056579 +258550 Olfr869 MGI:MGI:3030703|Ensembl:ENSMUSG00000058491 +258551 Olfr866 MGI:MGI:3030700|Ensembl:ENSMUSG00000050803|Vega:OTTMUSG00000061727 +258552 Olfr868 MGI:MGI:3030702|Ensembl:ENSMUSG00000044106 +258553 Olfr872 MGI:MGI:3030706|Ensembl:ENSMUSG00000066897 +258554 Olfr873 MGI:MGI:3030707|Ensembl:ENSMUSG00000049028 +258555 Olfr862 MGI:MGI:3030696|Ensembl:ENSMUSG00000063842|Vega:OTTMUSG00000061699 +258557 Olfr836 MGI:MGI:3030670|Ensembl:ENSMUSG00000059303|Vega:OTTMUSG00000061202 +258558 Olfr837 MGI:MGI:3030671|Ensembl:ENSMUSG00000110621|Vega:OTTMUSG00000061203 +258559 Olfr830 MGI:MGI:3030664|Ensembl:ENSMUSG00000062868|Vega:OTTMUSG00000061150 +258560 Olfr843 MGI:MGI:3030677|Ensembl:ENSMUSG00000048391|Vega:OTTMUSG00000061256 +258561 Olfr1012 MGI:MGI:3030846|Ensembl:ENSMUSG00000075210|Vega:OTTMUSG00000013553 +258562 Olfr1014 MGI:MGI:3030848|Ensembl:ENSMUSG00000059379|Vega:OTTMUSG00000013554 +258563 Olfr1006 MGI:MGI:3030840|Ensembl:ENSMUSG00000075211|Vega:OTTMUSG00000013518 +258564 Olfr1015 MGI:MGI:3030849|Ensembl:ENSMUSG00000033850|Vega:OTTMUSG00000013551 +258565 Olfr1009 MGI:MGI:3030843|Ensembl:ENSMUSG00000043226|Vega:OTTMUSG00000013558 +258566 Olfr1002 MGI:MGI:3030836|Ensembl:ENSMUSG00000075214|Vega:OTTMUSG00000013504 +258568 Olfr1457 MGI:MGI:3031291|Ensembl:ENSMUSG00000061637|Vega:OTTMUSG00000059468 +258569 Olfr459 MGI:MGI:3030293|Ensembl:ENSMUSG00000045479|Vega:OTTMUSG00000051433 +258570 Olfr1043 MGI:MGI:3030877|Ensembl:ENSMUSG00000075201|Vega:OTTMUSG00000013657 +258571 Olfr1033 MGI:MGI:3030867|Ensembl:ENSMUSG00000045392|Vega:OTTMUSG00000013597 +258572 Olfr1032 MGI:MGI:3030866|Ensembl:ENSMUSG00000042796|Vega:OTTMUSG00000013589 +258573 Olfr1020 MGI:MGI:3030854|Ensembl:ENSMUSG00000046975|Vega:OTTMUSG00000013586 +258574 Olfr1021-ps1 MGI:MGI:3030855 +258575 Olfr1046 MGI:MGI:3030880|Ensembl:ENSMUSG00000075197|Vega:OTTMUSG00000013659 +258577 Olfr1026 MGI:MGI:3030860|Ensembl:ENSMUSG00000042863|Vega:OTTMUSG00000013591 +258579 Olfr1018 MGI:MGI:3030852|Ensembl:ENSMUSG00000043892|Vega:OTTMUSG00000013550 +258580 Olfr1023 MGI:MGI:3030857|Ensembl:ENSMUSG00000050128|Vega:OTTMUSG00000013592 +258581 Olfr1030 MGI:MGI:3030864|Ensembl:ENSMUSG00000044923|Vega:OTTMUSG00000013598 +258582 Olfr1022 MGI:MGI:3030856|Ensembl:ENSMUSG00000057761|Vega:OTTMUSG00000013587 +258583 Olfr1085 MGI:MGI:3030919|Ensembl:ENSMUSG00000075176|Vega:OTTMUSG00000013676 +258584 Olfr1101 MGI:MGI:3030935|Ensembl:ENSMUSG00000075167|Vega:OTTMUSG00000013695 +258585 Olfr1086 MGI:MGI:3030920|Ensembl:ENSMUSG00000075175|Vega:OTTMUSG00000013674 +258586 Olfr1111 MGI:MGI:3030945|Ensembl:ENSMUSG00000075158|Vega:OTTMUSG00000013788 +258587 Olfr1100 MGI:MGI:3030934|Ensembl:ENSMUSG00000070875|Vega:OTTMUSG00000013703 +258589 Olfr703 MGI:MGI:3030537|Ensembl:ENSMUSG00000073901|Vega:OTTMUSG00000059719 +258590 Olfr702 MGI:MGI:3030536|Ensembl:ENSMUSG00000056863|Vega:OTTMUSG00000059683 +258591 Olfr695 MGI:MGI:3030529|Ensembl:ENSMUSG00000108948|Vega:OTTMUSG00000059676 +258592 Olfr697 MGI:MGI:3030531|Ensembl:ENSMUSG00000051591|Vega:OTTMUSG00000059678 +258593 Olfr700 MGI:MGI:3030534|Ensembl:ENSMUSG00000094493|Vega:OTTMUSG00000059681 +258594 Olfr710 MGI:MGI:3030544|Ensembl:ENSMUSG00000045581|Vega:OTTMUSG00000059726 +258595 Olfr698 MGI:MGI:3030532|Ensembl:ENSMUSG00000059087|Vega:OTTMUSG00000059679 +258597 Olfr716 MGI:MGI:3030550|Ensembl:ENSMUSG00000073896|Vega:OTTMUSG00000059739 +258598 Olfr828 MGI:MGI:3030662|Ensembl:ENSMUSG00000078116|Vega:OTTMUSG00000061148 +258600 Olfr270 MGI:MGI:3030104|Ensembl:ENSMUSG00000070983|Vega:OTTMUSG00000007115 +258601 Olfr984 MGI:MGI:3030818|Ensembl:ENSMUSG00000045812|Vega:OTTMUSG00000062412 +258602 Olfr150 MGI:MGI:2659178|Ensembl:ENSMUSG00000094353|Vega:OTTMUSG00000062390 +258603 Olfr972 MGI:MGI:3030806|Ensembl:ENSMUSG00000094449|Vega:OTTMUSG00000062398 +258604 Olfr970 MGI:MGI:3030804|Ensembl:ENSMUSG00000095774|Vega:OTTMUSG00000062395 +258605 Olfr968 MGI:MGI:3030802|Ensembl:ENSMUSG00000095903|Vega:OTTMUSG00000062392 +258606 Olfr229 MGI:MGI:3030063|Ensembl:ENSMUSG00000095390|Vega:OTTMUSG00000062399 +258607 Olfr971 MGI:MGI:3030805|Ensembl:ENSMUSG00000093934|Vega:OTTMUSG00000062397 +258608 Olfr986 MGI:MGI:3030820|Ensembl:ENSMUSG00000051095|Vega:OTTMUSG00000062414 +258609 Olfr305 MGI:MGI:3030139|Ensembl:ENSMUSG00000055571|Vega:OTTMUSG00000037763 +258610 Olfr307 MGI:MGI:3030141|Ensembl:ENSMUSG00000055610|Vega:OTTMUSG00000037761 +258611 Olfr297 MGI:MGI:3030131|Ensembl:ENSMUSG00000057067|Vega:OTTMUSG00000037770 +258612 Olfr303 MGI:MGI:3030137|Ensembl:ENSMUSG00000039608|Vega:OTTMUSG00000037765 +258613 Olfr292 MGI:MGI:3030126|Ensembl:ENSMUSG00000060688|Vega:OTTMUSG00000037776 +258614 Olfr308 MGI:MGI:3030142|Ensembl:ENSMUSG00000054498|Vega:OTTMUSG00000037760 +258615 Olfr360 MGI:MGI:3030194|Ensembl:ENSMUSG00000083361|Vega:OTTMUSG00000012221 +258616 Olfr357 MGI:MGI:3030191|Ensembl:ENSMUSG00000055838|Vega:OTTMUSG00000012204 +258617 Olfr356 MGI:MGI:3030190|Ensembl:ENSMUSG00000070943|Vega:OTTMUSG00000012229 +258618 Olfr355 MGI:MGI:3030189|Ensembl:ENSMUSG00000075380|Vega:OTTMUSG00000012234 +258620 Olfr350 MGI:MGI:3030184|Ensembl:ENSMUSG00000050015|Vega:OTTMUSG00000012203 +258621 Olfr344 MGI:MGI:3030178|Ensembl:ENSMUSG00000096822|Vega:OTTMUSG00000012230 +258622 Olfr121 MGI:MGI:2177504|Ensembl:ENSMUSG00000060017|Vega:OTTMUSG00000037472 +258623 Olfr123 MGI:MGI:2177506|Ensembl:ENSMUSG00000045202|Vega:OTTMUSG00000037474 +258624 Olfr120 MGI:MGI:2177503|Ensembl:ENSMUSG00000063994|Vega:OTTMUSG00000037471 +258625 Olfr116 MGI:MGI:2177499|Ensembl:ENSMUSG00000061336|Vega:OTTMUSG00000037465 +258626 Olfr1501 MGI:MGI:3031335|Ensembl:ENSMUSG00000057270|Vega:OTTMUSG00000059638 +258627 Olfr1504 MGI:MGI:3031338|Ensembl:ENSMUSG00000059105|Vega:OTTMUSG00000059689 +258628 Olfr1489 MGI:MGI:3031323|Ensembl:ENSMUSG00000045678|Vega:OTTMUSG00000059539 +258629 Olfr1487 MGI:MGI:3031321|Ensembl:ENSMUSG00000094846 +258630 Olfr1141 MGI:MGI:3030975|Ensembl:ENSMUSG00000075148|Vega:OTTMUSG00000013833 +258631 Olfr1151 MGI:MGI:3030985|Ensembl:ENSMUSG00000047039|Vega:OTTMUSG00000013875 +258632 Olfr1138 MGI:MGI:3030972|Ensembl:ENSMUSG00000075149|Vega:OTTMUSG00000013849 +258633 Olfr1153 MGI:MGI:3030987|Ensembl:ENSMUSG00000048197|Vega:OTTMUSG00000013866 +258634 Olfr1164 MGI:MGI:3030998|Ensembl:ENSMUSG00000075136|Vega:OTTMUSG00000013907 +258635 Olfr1140 MGI:MGI:3030974|Ensembl:ENSMUSG00000068817|Vega:OTTMUSG00000013840 +258636 Olfr1155 MGI:MGI:3030989|Ensembl:ENSMUSG00000075145|Vega:OTTMUSG00000013873 +258638 Olfr1163 MGI:MGI:3030997|Ensembl:ENSMUSG00000075137|Vega:OTTMUSG00000013904 +258639 Olfr1158 MGI:MGI:3030992|Ensembl:ENSMUSG00000062793|Vega:OTTMUSG00000013891 +258640 Olfr152 MGI:MGI:1313139|Ensembl:ENSMUSG00000068816|Vega:OTTMUSG00000013836 +258641 Olfr1154 MGI:MGI:3030988|Ensembl:ENSMUSG00000075146|Vega:OTTMUSG00000013865 +258642 Olfr1165-ps MGI:MGI:3030999 +258643 Olfr1160 MGI:MGI:3030994|Ensembl:ENSMUSG00000075141|Vega:OTTMUSG00000013903 +258644 Olfr1166 MGI:MGI:3031000|Ensembl:ENSMUSG00000101078|Vega:OTTMUSG00000013908 +258645 Olfr418 MGI:MGI:3030252|Ensembl:ENSMUSG00000049605|Vega:OTTMUSG00000050169 +258647 Olfr435 MGI:MGI:3030269|Ensembl:ENSMUSG00000048693|Vega:OTTMUSG00000057770 +258648 Olfr237-ps1 MGI:MGI:3030071|Ensembl:ENSMUSG00000094200|Vega:OTTMUSG00000057728 +258649 Olfr441 MGI:MGI:3030275|Ensembl:ENSMUSG00000094669|Vega:OTTMUSG00000057725 +258650 Olfr444 MGI:MGI:3030278|Ensembl:ENSMUSG00000073110|Vega:OTTMUSG00000057693 +258652 Olfr1131 MGI:MGI:3030965|Ensembl:ENSMUSG00000068819 +258653 Olfr1136 MGI:MGI:3030970|Ensembl:ENSMUSG00000075151|Vega:OTTMUSG00000013838 +258654 Olfr1135 MGI:MGI:3030969|Ensembl:ENSMUSG00000075153|Vega:OTTMUSG00000013832 +258655 Olfr1112 MGI:MGI:3030946|Ensembl:ENSMUSG00000044487|Vega:OTTMUSG00000013785 +258656 Olfr365 MGI:MGI:3030199|Ensembl:ENSMUSG00000059429|Vega:OTTMUSG00000012210 +258657 Olfr733 MGI:MGI:3030567|Ensembl:ENSMUSG00000090874|Vega:OTTMUSG00000058475 +258658 Olfr734 MGI:MGI:3030568|Ensembl:ENSMUSG00000045306|Vega:OTTMUSG00000058476 +258659 Olfr732 MGI:MGI:3030566|Ensembl:ENSMUSG00000091873|Vega:OTTMUSG00000058474 +258660 Olfr736 MGI:MGI:3030570|Ensembl:ENSMUSG00000047716|Vega:OTTMUSG00000058478 +258661 Olfr740 MGI:MGI:3030574|Ensembl:ENSMUSG00000095917|Vega:OTTMUSG00000058482 +258662 Olfr738 MGI:MGI:3030572|Ensembl:ENSMUSG00000094692|Vega:OTTMUSG00000058480 +258663 Olfr739 MGI:MGI:3030573|Ensembl:ENSMUSG00000057903|Vega:OTTMUSG00000058481 +258665 Olfr815 MGI:MGI:3030649|Ensembl:ENSMUSG00000061961|Vega:OTTMUSG00000056632 +258666 Olfr822 MGI:MGI:3030656|Ensembl:ENSMUSG00000058251|Vega:OTTMUSG00000056654 +258667 Olfr816 MGI:MGI:3030650|Ensembl:ENSMUSG00000063715|Vega:OTTMUSG00000056633 +258668 Olfr823 MGI:MGI:3030657|Ensembl:ENSMUSG00000096747|Vega:OTTMUSG00000056656 +258669 Olfr824 MGI:MGI:3030658|Ensembl:ENSMUSG00000095804|Vega:OTTMUSG00000056688 +258670 Olfr820 MGI:MGI:3030654|Ensembl:ENSMUSG00000048745|Vega:OTTMUSG00000056652 +258671 Olfr826 MGI:MGI:3030660|Ensembl:ENSMUSG00000059862|Vega:OTTMUSG00000056691 +258672 Olfr825 MGI:MGI:3030659|Ensembl:ENSMUSG00000058084|Vega:OTTMUSG00000056690 +258673 Olfr1428 MGI:MGI:3031262|Ensembl:ENSMUSG00000067524|Vega:OTTMUSG00000059440 +258674 Olfr1427 MGI:MGI:3031261|Ensembl:ENSMUSG00000067525|Vega:OTTMUSG00000059439 +258675 Olfr1423 MGI:MGI:3031257|Ensembl:ENSMUSG00000067529|Vega:OTTMUSG00000059435 +258676 Olfr1424 MGI:MGI:3031258|Ensembl:ENSMUSG00000067528|Vega:OTTMUSG00000059436 +258677 Olfr76 MGI:MGI:2153205|Ensembl:ENSMUSG00000067522|Vega:OTTMUSG00000059441 +258678 Olfr1441 MGI:MGI:3031275|Ensembl:ENSMUSG00000050815|Vega:OTTMUSG00000059451 +258679 Olfr1440 MGI:MGI:3031274|Ensembl:ENSMUSG00000046650|Vega:OTTMUSG00000059450 +258680 Olfr1434 MGI:MGI:3031268|Ensembl:ENSMUSG00000095640|Vega:OTTMUSG00000059444 +258681 Olfr235 MGI:MGI:3030069|Ensembl:ENSMUSG00000060049|Vega:OTTMUSG00000042681 +258682 Olfr1436 MGI:MGI:3031270|Ensembl:ENSMUSG00000067513|Vega:OTTMUSG00000059446 +258683 Olfr262 MGI:MGI:3030096|Ensembl:ENSMUSG00000067519|Vega:OTTMUSG00000042679 +258684 Olfr1459 MGI:MGI:3031293|Ensembl:ENSMUSG00000057503|Vega:OTTMUSG00000059470 +258685 Olfr1472 MGI:MGI:3031306|Ensembl:ENSMUSG00000095189|Vega:OTTMUSG00000059509 +258686 Olfr1467 MGI:MGI:3031301|Ensembl:ENSMUSG00000049015|Vega:OTTMUSG00000059503 +258687 Olfr1454 MGI:MGI:3031288|Ensembl:ENSMUSG00000094986|Vega:OTTMUSG00000059465 +258688 Olfr1462 MGI:MGI:3031296|Ensembl:ENSMUSG00000094721|Vega:OTTMUSG00000059498 +258689 Olfr1466 MGI:MGI:3031300|Ensembl:ENSMUSG00000096485|Vega:OTTMUSG00000059502 +258690 Olfr1469 MGI:MGI:3031303|Ensembl:ENSMUSG00000063777|Vega:OTTMUSG00000059506 +258691 Olfr1477 MGI:MGI:3031311|Ensembl:ENSMUSG00000071629|Vega:OTTMUSG00000059527 +258692 Olfr1442 MGI:MGI:3031276|Ensembl:ENSMUSG00000044441|Vega:OTTMUSG00000059452 +258693 Olfr1443 MGI:MGI:3031277|Ensembl:ENSMUSG00000045030|Vega:OTTMUSG00000059453 +258694 Olfr1445 MGI:MGI:3031279|Ensembl:ENSMUSG00000045126|Vega:OTTMUSG00000059455 +258695 Olfr1453 MGI:MGI:3031287|Ensembl:ENSMUSG00000094755|Vega:OTTMUSG00000059464 +258696 Olfr1448 MGI:MGI:3031282|Ensembl:ENSMUSG00000048456|Vega:OTTMUSG00000059458 +258697 Olfr1444 MGI:MGI:3031278|Ensembl:ENSMUSG00000046272|Vega:OTTMUSG00000059454 +258698 Olfr1447 MGI:MGI:3031281|Ensembl:ENSMUSG00000060303|Vega:OTTMUSG00000059457 +258699 Olfr1446 MGI:MGI:3031280|Ensembl:ENSMUSG00000057817|Vega:OTTMUSG00000059456 +258700 Olfr1451 MGI:MGI:3031285|Ensembl:ENSMUSG00000046913|Vega:OTTMUSG00000059462 +258701 Olfr401 MGI:MGI:3030235|Ensembl:ENSMUSG00000070380|Vega:OTTMUSG00000006166 +258702 Olfr410 MGI:MGI:3030244|Ensembl:ENSMUSG00000063116|Vega:OTTMUSG00000006178 +258703 Olfr402 MGI:MGI:3030236|Ensembl:ENSMUSG00000070379|Vega:OTTMUSG00000006168 +258704 Olfr411 MGI:MGI:3030245|Ensembl:ENSMUSG00000054406|Vega:OTTMUSG00000006179 +258705 Olfr398 MGI:MGI:3030232|Ensembl:ENSMUSG00000049041|Vega:OTTMUSG00000006160 +258706 Olfr43 MGI:MGI:1333770|Ensembl:ENSMUSG00000070377|Vega:OTTMUSG00000006169 +258707 Olfr1343-ps1 MGI:MGI:3031177 +258708 Olfr1342 MGI:MGI:3031176|Ensembl:ENSMUSG00000043383|Vega:OTTMUSG00000008742 +258709 Olfr248 MGI:MGI:3030082|Ensembl:ENSMUSG00000059503|Vega:OTTMUSG00000050221 +258710 Olfr419 MGI:MGI:3030253|Ensembl:ENSMUSG00000050788|Vega:OTTMUSG00000050218 +258711 Olfr432 MGI:MGI:3030266|Ensembl:ENSMUSG00000047048|Vega:OTTMUSG00000050208 +258712 Olfr433 MGI:MGI:3030267|Ensembl:ENSMUSG00000045381|Vega:OTTMUSG00000050207 +258713 Olfr430 MGI:MGI:3030264|Ensembl:ENSMUSG00000050134|Vega:OTTMUSG00000050210 +258715 Olfr421-ps1 MGI:MGI:3030255|Ensembl:ENSMUSG00000091950|Vega:OTTMUSG00000042404 +258716 Olfr424 MGI:MGI:3030258|Ensembl:ENSMUSG00000051528|Vega:OTTMUSG00000050215 +258717 Olfr429 MGI:MGI:3030263|Ensembl:ENSMUSG00000049528|Vega:OTTMUSG00000050211 +258718 Olfr513 MGI:MGI:3030347|Ensembl:ENSMUSG00000051200|Vega:OTTMUSG00000060088 +258719 Olfr512 MGI:MGI:3030346|Ensembl:ENSMUSG00000056946|Vega:OTTMUSG00000060087 +258720 Olfr516 MGI:MGI:3030350|Ensembl:ENSMUSG00000062434|Vega:OTTMUSG00000060092 +258721 Olfr514 MGI:MGI:3030348|Ensembl:ENSMUSG00000066241|Vega:OTTMUSG00000060090 +258722 Olfr611 MGI:MGI:3030445|Ensembl:ENSMUSG00000096584|Vega:OTTMUSG00000019087 +258723 Olfr781 MGI:MGI:3030615|Ensembl:ENSMUSG00000095138|Vega:OTTMUSG00000056562 +258724 Olfr784 MGI:MGI:3030618|Ensembl:ENSMUSG00000094347|Vega:OTTMUSG00000056565 +258725 Olfr1095 MGI:MGI:3030929|Ensembl:ENSMUSG00000075171|Vega:OTTMUSG00000013701 +258726 Olfr599 MGI:MGI:3030433|Ensembl:ENSMUSG00000073950|Vega:OTTMUSG00000019091 +258727 Olfr488 MGI:MGI:3030322|Ensembl:ENSMUSG00000096465|Vega:OTTMUSG00000059972 +258728 Olfr482 MGI:MGI:3030316|Ensembl:ENSMUSG00000059031|Vega:OTTMUSG00000059965 +258729 Olfr478 MGI:MGI:3030312|Ensembl:ENSMUSG00000094426|Vega:OTTMUSG00000059960 +258730 Olfr483 MGI:MGI:3030317|Ensembl:ENSMUSG00000078118|Vega:OTTMUSG00000059966 +258731 Olfr491 MGI:MGI:3030325|Ensembl:ENSMUSG00000094612|Vega:OTTMUSG00000059978 +258732 Olfr494 MGI:MGI:3030328|Ensembl:ENSMUSG00000109631|Vega:OTTMUSG00000059981 +258733 Olfr497 MGI:MGI:3030331|Ensembl:ENSMUSG00000095239|Vega:OTTMUSG00000059984 +258734 Olfr502 MGI:MGI:3030336|Ensembl:ENSMUSG00000058014|Vega:OTTMUSG00000059991 +258735 Olfr1493-ps1 MGI:MGI:3031327 +258736 Olfr1497 MGI:MGI:3031331|Ensembl:ENSMUSG00000044040|Vega:OTTMUSG00000059634 +258737 Olfr1316 MGI:MGI:3031150|Ensembl:ENSMUSG00000109801|Vega:OTTMUSG00000015105 +258738 Olfr507 MGI:MGI:3030341|Ensembl:ENSMUSG00000061000|Vega:OTTMUSG00000060082 +258739 Olfr1362 MGI:MGI:3031196|Ensembl:ENSMUSG00000051258|Vega:OTTMUSG00000000438 +258740 Olfr957 MGI:MGI:3030791|Ensembl:ENSMUSG00000095322|Vega:OTTMUSG00000062349 +258741 Olfr935 MGI:MGI:3030769|Ensembl:ENSMUSG00000059595|Vega:OTTMUSG00000062247 +258742 Olfr146 MGI:MGI:2660711|Ensembl:ENSMUSG00000058820|Vega:OTTMUSG00000062256 +258743 Olfr661 MGI:MGI:3030495|Ensembl:ENSMUSG00000073920|Vega:OTTMUSG00000060530 +258744 Olfr875 MGI:MGI:3030709|Ensembl:ENSMUSG00000058628|Vega:OTTMUSG00000061754 +258745 Olfr689 MGI:MGI:3030523|Ensembl:ENSMUSG00000073907|Vega:OTTMUSG00000060654 +258746 Olfr648 MGI:MGI:3030482|Ensembl:ENSMUSG00000042909|Vega:OTTMUSG00000019045 +258747 Olfr1106 MGI:MGI:3030940|Ensembl:ENSMUSG00000075164|Vega:OTTMUSG00000013715 +258748 Olfr1195 MGI:MGI:3031029|Ensembl:ENSMUSG00000075121|Vega:OTTMUSG00000013993 +258749 Olfr556 MGI:MGI:3030390|Ensembl:ENSMUSG00000073969|Vega:OTTMUSG00000060023 +258750 Olfr551 MGI:MGI:3030385|Ensembl:ENSMUSG00000073974|Vega:OTTMUSG00000060018 +258751 Olfr608 MGI:MGI:3030442|Ensembl:ENSMUSG00000073948|Vega:OTTMUSG00000019065 +258752 Olfr583 MGI:MGI:3030417|Ensembl:ENSMUSG00000073960|Vega:OTTMUSG00000019034 +258753 Olfr678 MGI:MGI:3030512|Ensembl:ENSMUSG00000073913|Vega:OTTMUSG00000060644 +258754 Olfr214 MGI:MGI:3030048|Ensembl:ENSMUSG00000051046|Vega:OTTMUSG00000057305 +258755 Olfr672 MGI:MGI:3030506|Ensembl:ENSMUSG00000051172|Vega:OTTMUSG00000060552 +258756 Olfr414 MGI:MGI:3030248|Ensembl:ENSMUSG00000051509|Vega:OTTMUSG00000050222 +258757 Olfr1013 MGI:MGI:3030847|Ensembl:ENSMUSG00000053287|Vega:OTTMUSG00000013557 +258758 Olfr1406 MGI:MGI:3031240|Ensembl:ENSMUSG00000058981|Vega:OTTMUSG00000050165 +258759 Olfr1408 MGI:MGI:3031242|Ensembl:ENSMUSG00000062527|Vega:OTTMUSG00000050163 +258762 Olfr1109 MGI:MGI:3030943|Ensembl:ENSMUSG00000075161|Vega:OTTMUSG00000013779 +258763 Olfr1104 MGI:MGI:3030938|Ensembl:ENSMUSG00000075166|Vega:OTTMUSG00000013719 +258764 Olfr1099 MGI:MGI:3030933|Ensembl:ENSMUSG00000075168|Vega:OTTMUSG00000013696 +258765 Olfr1110 MGI:MGI:3030944|Ensembl:ENSMUSG00000075159|Vega:OTTMUSG00000013793 +258766 Olfr259 MGI:MGI:3030093|Ensembl:ENSMUSG00000075160|Vega:OTTMUSG00000013792 +258767 Olfr1176 MGI:MGI:3031010|Ensembl:ENSMUSG00000050023|Vega:OTTMUSG00000013946 +258768 Olfr1189 MGI:MGI:3031023|Ensembl:ENSMUSG00000068808|Vega:OTTMUSG00000013988 +258769 Olfr508 MGI:MGI:3030342|Ensembl:ENSMUSG00000063764|Vega:OTTMUSG00000060083 +258770 Olfr472 MGI:MGI:3030306|Ensembl:ENSMUSG00000073893|Vega:OTTMUSG00000059952 +258771 Olfr473 MGI:MGI:3030307|Ensembl:ENSMUSG00000095212|Vega:OTTMUSG00000059953 +258772 Olfr821 MGI:MGI:3030655|Ensembl:ENSMUSG00000044897|Vega:OTTMUSG00000056653 +258773 Olfr818 MGI:MGI:3030652|Ensembl:ENSMUSG00000058071|Vega:OTTMUSG00000056635 +258774 Olfr1208 MGI:MGI:3031042|Ensembl:ENSMUSG00000075114|Vega:OTTMUSG00000014041 +258775 Olfr196 MGI:MGI:3030030|Ensembl:ENSMUSG00000096695|Vega:OTTMUSG00000059124 +258776 Olfr715 MGI:MGI:3030549|Ensembl:ENSMUSG00000060503|Vega:OTTMUSG00000059738 +258777 Olfr922 MGI:MGI:3030756|Ensembl:ENSMUSG00000043911|Vega:OTTMUSG00000062203 +258778 Olfr921 MGI:MGI:3030755|Ensembl:ENSMUSG00000049926|Vega:OTTMUSG00000062201 +258780 Olfr916 MGI:MGI:3030750|Ensembl:ENSMUSG00000094701|Vega:OTTMUSG00000062192 +258781 Olfr915 MGI:MGI:3030749|Ensembl:ENSMUSG00000057444|Vega:OTTMUSG00000062190 +258782 Olfr914 MGI:MGI:3030748|Ensembl:ENSMUSG00000047050|Vega:OTTMUSG00000062189 +258783 Olfr920 MGI:MGI:3030754|Ensembl:ENSMUSG00000061039|Vega:OTTMUSG00000062199 +258784 Olfr1245 MGI:MGI:3031079|Ensembl:ENSMUSG00000111456|Vega:OTTMUSG00000014155 +258785 Olfr1230 MGI:MGI:3031064|Ensembl:ENSMUSG00000075094|Vega:OTTMUSG00000014020 +258786 Olfr1238 MGI:MGI:3031072|Ensembl:ENSMUSG00000111517|Vega:OTTMUSG00000014161 +258787 Olfr1248 MGI:MGI:3031082|Ensembl:ENSMUSG00000111239|Vega:OTTMUSG00000014158 +258788 Olfr1246 MGI:MGI:3031080|Ensembl:ENSMUSG00000111715|Vega:OTTMUSG00000014151 +258789 Olfr1271 MGI:MGI:3031105|Ensembl:ENSMUSG00000075062|Vega:OTTMUSG00000014224 +258790 Olfr1263 MGI:MGI:3031097|Ensembl:ENSMUSG00000059112|Vega:OTTMUSG00000014232 +258791 Olfr812 MGI:MGI:3030646|Ensembl:ENSMUSG00000049052|Vega:OTTMUSG00000056629 +258792 Olfr1499 MGI:MGI:3031333|Ensembl:ENSMUSG00000045395|Vega:OTTMUSG00000059636 +258793 Olfr1502 MGI:MGI:3031336|Ensembl:ENSMUSG00000056858|Vega:OTTMUSG00000059687 +258794 Olfr878 MGI:MGI:3030712|Ensembl:ENSMUSG00000066747|Vega:OTTMUSG00000061758 +258797 Olfr904 MGI:MGI:3030738|Ensembl:ENSMUSG00000094380|Vega:OTTMUSG00000062123 +258798 Olfr902 MGI:MGI:3030736|Ensembl:ENSMUSG00000049334|Vega:OTTMUSG00000062121 +258799 Olfr906 MGI:MGI:3030740|Ensembl:ENSMUSG00000039962|Vega:OTTMUSG00000062125 +258800 Olfr905 MGI:MGI:3030739|Ensembl:ENSMUSG00000096794|Vega:OTTMUSG00000062124 +258801 Olfr907 MGI:MGI:3030741|Ensembl:ENSMUSG00000094810|Vega:OTTMUSG00000062126 +258802 Olfr143 MGI:MGI:2177526|Ensembl:ENSMUSG00000094778|Vega:OTTMUSG00000061827 +258803 Olfr136 MGI:MGI:2177519|Ensembl:ENSMUSG00000096840|Vega:OTTMUSG00000037365 +258804 Olfr1240 MGI:MGI:3031074|Ensembl:ENSMUSG00000111174|Vega:OTTMUSG00000014153 +258805 Olfr1426 MGI:MGI:3031260|Ensembl:ENSMUSG00000044994|Vega:OTTMUSG00000059438 +258806 Olfr912 MGI:MGI:3030746|Ensembl:ENSMUSG00000111448|Vega:OTTMUSG00000062187 +258807 Olfr910 MGI:MGI:3030744|Ensembl:ENSMUSG00000060114|Vega:OTTMUSG00000062186 +258808 Olfr620 MGI:MGI:3030454|Ensembl:ENSMUSG00000045132|Vega:OTTMUSG00000019081 +258809 Olfr651 MGI:MGI:3030485|Ensembl:ENSMUSG00000073928|Vega:OTTMUSG00000019200 +258810 Olfr665 MGI:MGI:3030499|Ensembl:ENSMUSG00000073917|Vega:OTTMUSG00000060545 +258811 Olfr926 MGI:MGI:3030760|Ensembl:ENSMUSG00000064333|Vega:OTTMUSG00000062208 +258812 Olfr923 MGI:MGI:3030757|Ensembl:ENSMUSG00000044798|Vega:OTTMUSG00000062204 +258814 Olfr1156 MGI:MGI:3030990|Ensembl:ENSMUSG00000075144|Vega:OTTMUSG00000013870 +258815 Olfr1218 MGI:MGI:3031052|Ensembl:ENSMUSG00000075105|Vega:OTTMUSG00000014063 +258816 Olfr466 MGI:MGI:3030300|Ensembl:ENSMUSG00000049806|Vega:OTTMUSG00000058346 +258817 Olfr655 MGI:MGI:3030489|Ensembl:ENSMUSG00000051182|Vega:OTTMUSG00000019199 +258818 Olfr629 MGI:MGI:3030463|Ensembl:ENSMUSG00000047545|Vega:OTTMUSG00000019077 +258819 Olfr640 MGI:MGI:3030474|Ensembl:ENSMUSG00000066262|Vega:OTTMUSG00000019068 +258820 Olfr1184 MGI:MGI:3031018|Ensembl:ENSMUSG00000051424|Vega:OTTMUSG00000013977 +258821 Olfr273 MGI:MGI:3030107|Ensembl:ENSMUSG00000049648|Vega:OTTMUSG00000007117 +258822 Olfr39 MGI:MGI:1313142|Ensembl:ENSMUSG00000059623 +258823 Olfr969 MGI:MGI:3030803|Ensembl:ENSMUSG00000094254|Vega:OTTMUSG00000062394 +258824 Olfr983 MGI:MGI:3030817|Ensembl:ENSMUSG00000044205|Vega:OTTMUSG00000062411 +258825 Olfr975 MGI:MGI:3030809|Ensembl:ENSMUSG00000043331|Vega:OTTMUSG00000062402 +258826 Olfr27 MGI:MGI:109308|Ensembl:ENSMUSG00000049708|Vega:OTTMUSG00000062275 +258828 Olfr133 MGI:MGI:2177516|Ensembl:ENSMUSG00000063240 +258829 Olfr134 MGI:MGI:2177517|Ensembl:ENSMUSG00000096009|Vega:OTTMUSG00000037360 +258830 Olfr103 MGI:MGI:2177486|Ensembl:ENSMUSG00000049618|Vega:OTTMUSG00000037418 +258831 Olfr101 MGI:MGI:2177484|Ensembl:ENSMUSG00000092077|Vega:OTTMUSG00000037416 +258832 Olfr109 MGI:MGI:2177492|Ensembl:ENSMUSG00000029184|Vega:OTTMUSG00000037431 +258833 Olfr1132 MGI:MGI:3030966|Ensembl:ENSMUSG00000068818|Vega:OTTMUSG00000013831 +258834 Olfr1126 MGI:MGI:3030960|Ensembl:ENSMUSG00000058194|Vega:OTTMUSG00000013791 +258835 Olfr1130 MGI:MGI:3030964|Ensembl:ENSMUSG00000059205|Vega:OTTMUSG00000013834 +258836 Olfr272 MGI:MGI:3030106|Ensembl:ENSMUSG00000051593|Vega:OTTMUSG00000007116 +258837 Olfr545 MGI:MGI:3030379|Ensembl:ENSMUSG00000044824|Vega:OTTMUSG00000060013 +258838 Olfr617 MGI:MGI:3030451|Ensembl:ENSMUSG00000073946|Vega:OTTMUSG00000019031 +258840 Olfr1097 MGI:MGI:3030931|Ensembl:ENSMUSG00000075170|Vega:OTTMUSG00000013705 +258841 Olfr1107 MGI:MGI:3030941|Ensembl:ENSMUSG00000075163|Vega:OTTMUSG00000013716 +258842 Olfr1098 MGI:MGI:3030932|Ensembl:ENSMUSG00000075169|Vega:OTTMUSG00000013694 +258843 Olfr1087 MGI:MGI:3030921|Ensembl:ENSMUSG00000075174|Vega:OTTMUSG00000013677 +258844 Olfr1090 MGI:MGI:3030924|Ensembl:ENSMUSG00000075172|Vega:OTTMUSG00000013673 +258845 Olfr1161 MGI:MGI:3030995|Ensembl:ENSMUSG00000045150|Vega:OTTMUSG00000013909 +258846 Olfr1157 MGI:MGI:3030991|Ensembl:ENSMUSG00000075143|Vega:OTTMUSG00000013878 +258850 Olfr295 MGI:MGI:3030129|Ensembl:ENSMUSG00000059319|Vega:OTTMUSG00000037773 +258851 Olfr1339 MGI:MGI:3031173|Ensembl:ENSMUSG00000070820|Vega:OTTMUSG00000008740 +258852 Olfr1341 MGI:MGI:3031175|Ensembl:ENSMUSG00000046790|Vega:OTTMUSG00000008745 +258853 Olfr982 MGI:MGI:3030816|Ensembl:ENSMUSG00000049010|Vega:OTTMUSG00000062410 +258854 Olfr985 MGI:MGI:3030819|Ensembl:ENSMUSG00000049073|Vega:OTTMUSG00000062413 +258855 Olfr964-ps1 MGI:MGI:3030798 +258856 Olfr271-ps1 MGI:MGI:3030105 +258857 Olfr275 MGI:MGI:3030109|Ensembl:ENSMUSG00000089717|Vega:OTTMUSG00000007057 +258858 Olfr371 MGI:MGI:3030205|Ensembl:ENSMUSG00000051952|Vega:OTTMUSG00000061138 +258859 Olfr161 MGI:MGI:3032605|Ensembl:ENSMUSG00000051003|Vega:OTTMUSG00000058769 +258861 Olfr763 MGI:MGI:3030597|Ensembl:ENSMUSG00000063374|Vega:OTTMUSG00000056475 +258862 Olfr770 MGI:MGI:3030604|Ensembl:ENSMUSG00000047868|Vega:OTTMUSG00000056483 +258863 Olfr768 MGI:MGI:3030602|Ensembl:ENSMUSG00000050198|Vega:OTTMUSG00000056481 +258865 Olfr992 MGI:MGI:3030826|Ensembl:ENSMUSG00000075221|Vega:OTTMUSG00000013481 +258866 Olfr1008 MGI:MGI:3030842|Ensembl:ENSMUSG00000050603|Vega:OTTMUSG00000013556 +258867 Olfr131 MGI:MGI:2177514|Ensembl:ENSMUSG00000043312|Vega:OTTMUSG00000037355 +258868 Olfr894 MGI:MGI:3030728|Ensembl:ENSMUSG00000070311|Vega:OTTMUSG00000061826 +258869 Olfr147 MGI:MGI:2660712|Ensembl:ENSMUSG00000049098|Vega:OTTMUSG00000062119 +258871 Olfr898 MGI:MGI:3030732|Ensembl:ENSMUSG00000094588|Vega:OTTMUSG00000062003 +258872 Olfr908 MGI:MGI:3030742|Ensembl:ENSMUSG00000110991|Vega:OTTMUSG00000062127 +258873 Olfr911-ps1 MGI:MGI:3030745|Ensembl:ENSMUSG00000062621|Vega:OTTMUSG00000062128 +258874 Olfr900 MGI:MGI:3030734 +258875 Olfr895 MGI:MGI:3030729|Ensembl:ENSMUSG00000096427|Vega:OTTMUSG00000061833 +258877 Olfr1395 MGI:MGI:3031229|Ensembl:ENSMUSG00000050763 +258879 Olfr330 MGI:MGI:3030164|Ensembl:ENSMUSG00000050818|Vega:OTTMUSG00000005743 +258880 Olfr218 MGI:MGI:3030052|Ensembl:ENSMUSG00000046643|Vega:OTTMUSG00000050166 +258881 Olfr1404 MGI:MGI:3031238|Ensembl:ENSMUSG00000049456|Vega:OTTMUSG00000050167 +258882 Olfr874 MGI:MGI:3030708|Ensembl:ENSMUSG00000063350|Vega:OTTMUSG00000061753 +258883 Olfr876 MGI:MGI:3030710|Ensembl:ENSMUSG00000066750|Vega:OTTMUSG00000061755 +258886 Olfr1299 MGI:MGI:3031133|Ensembl:ENSMUSG00000109219|Vega:OTTMUSG00000015070 +258887 Olfr1294 MGI:MGI:3031128|Ensembl:ENSMUSG00000109547|Vega:OTTMUSG00000015069 +258888 Olfr1298 MGI:MGI:3031132|Ensembl:ENSMUSG00000109487|Vega:OTTMUSG00000015083 +258889 Olfr1301 MGI:MGI:3031135|Ensembl:ENSMUSG00000057149|Vega:OTTMUSG00000015089 +258890 Olfr1297 MGI:MGI:3031131|Ensembl:ENSMUSG00000094858|Vega:OTTMUSG00000015079 +258891 Olfr1302 MGI:MGI:3031136|Ensembl:ENSMUSG00000044560|Vega:OTTMUSG00000015090 +258892 Olfr126 MGI:MGI:2177509|Ensembl:ENSMUSG00000109212|Vega:OTTMUSG00000037493 +258893 Olfr1225 MGI:MGI:3031059|Ensembl:ENSMUSG00000101918|Vega:OTTMUSG00000014017 +258894 Olfr1223 MGI:MGI:3031057|Ensembl:ENSMUSG00000075100|Vega:OTTMUSG00000014022 +258895 Olfr1216 MGI:MGI:3031050|Ensembl:ENSMUSG00000075107|Vega:OTTMUSG00000014069 +258896 Olfr1206 MGI:MGI:3031040|Ensembl:ENSMUSG00000062757|Vega:OTTMUSG00000014043 +258897 Olfr1201 MGI:MGI:3031035|Ensembl:ENSMUSG00000059023|Vega:OTTMUSG00000014053 +258898 Olfr1205 MGI:MGI:3031039|Ensembl:ENSMUSG00000057447|Vega:OTTMUSG00000014045 +258899 Olfr1214 MGI:MGI:3031048|Ensembl:ENSMUSG00000075110|Vega:OTTMUSG00000014044 +258900 Olfr1213 MGI:MGI:3031047|Ensembl:ENSMUSG00000075111|Vega:OTTMUSG00000014040 +258901 Olfr1219 MGI:MGI:3031053|Ensembl:ENSMUSG00000075104|Vega:OTTMUSG00000014066 +258902 Olfr1220 MGI:MGI:3031054|Ensembl:ENSMUSG00000101480|Vega:OTTMUSG00000014064 +258903 Olfr1217 MGI:MGI:3031051|Ensembl:ENSMUSG00000101391|Vega:OTTMUSG00000014068 +258904 Olfr1221 MGI:MGI:3031055|Ensembl:ENSMUSG00000075102|Vega:OTTMUSG00000014065 +258905 Olfr871 MGI:MGI:3030705|Ensembl:ENSMUSG00000061457|Vega:OTTMUSG00000061731 +258907 Olfr851 MGI:MGI:3030685|Ensembl:ENSMUSG00000052625|Vega:OTTMUSG00000061272 +258908 Olfr853 MGI:MGI:3030687|Ensembl:ENSMUSG00000051160|Vega:OTTMUSG00000061274 +258909 Olfr1282 MGI:MGI:3031116|Ensembl:ENSMUSG00000096554|Vega:OTTMUSG00000015185 +258910 Olfr1280 MGI:MGI:3031114|Ensembl:ENSMUSG00000109449|Vega:OTTMUSG00000015186 +258912 Olfr1378 MGI:MGI:3031212|Ensembl:ENSMUSG00000050343|Vega:OTTMUSG00000007889 +258913 Olfr1377 MGI:MGI:3031211|Ensembl:ENSMUSG00000061952|Vega:OTTMUSG00000007893 +258914 Olfr211 MGI:MGI:3030045|Ensembl:ENSMUSG00000053391|Vega:OTTMUSG00000056818 +258915 Olfr1348 MGI:MGI:3031182|Ensembl:ENSMUSG00000093877|Vega:OTTMUSG00000060114 +258917 Olfr1336 MGI:MGI:3031170|Ensembl:ENSMUSG00000048620|Vega:OTTMUSG00000060111 +258918 Olfr1346 MGI:MGI:3031180|Ensembl:ENSMUSG00000054938|Vega:OTTMUSG00000060112 +258919 Olfr1179 MGI:MGI:3031013|Ensembl:ENSMUSG00000075127|Vega:OTTMUSG00000013981 +258920 Olfr1180 MGI:MGI:3031014|Ensembl:ENSMUSG00000081836|Vega:OTTMUSG00000013976 +258921 Olfr1188 MGI:MGI:3031022|Ensembl:ENSMUSG00000068809|Vega:OTTMUSG00000013984 +258922 Olfr267 MGI:MGI:3030101|Ensembl:ENSMUSG00000043385|Vega:OTTMUSG00000007618 +258923 Olfr1 MGI:MGI:102698|Ensembl:ENSMUSG00000069823|Vega:OTTMUSG00000006133 +258924 Olfr376 MGI:MGI:3030210|Ensembl:ENSMUSG00000063881|Vega:OTTMUSG00000006131 +258925 Olfr20 MGI:MGI:109315|Ensembl:ENSMUSG00000062128|Vega:OTTMUSG00000006130 +258926 Olfr476 MGI:MGI:3030310|Ensembl:ENSMUSG00000095301|Vega:OTTMUSG00000059956 +258927 Olfr481 MGI:MGI:3030315|Ensembl:ENSMUSG00000054236|Vega:OTTMUSG00000059963 +258928 Olfr477 MGI:MGI:3030311|Ensembl:ENSMUSG00000096151|Vega:OTTMUSG00000059957 +258929 Olfr799 MGI:MGI:3030633|Ensembl:ENSMUSG00000094734|Vega:OTTMUSG00000056616 +258930 Olfr808 MGI:MGI:3030642|Ensembl:ENSMUSG00000049894|Vega:OTTMUSG00000056625 +258931 Olfr807 MGI:MGI:3030641|Ensembl:ENSMUSG00000050478|Vega:OTTMUSG00000056624 +258932 Olfr791 MGI:MGI:3030625|Ensembl:ENSMUSG00000047626|Vega:OTTMUSG00000056572 +258933 Olfr796 MGI:MGI:3030630|Ensembl:ENSMUSG00000052012|Vega:OTTMUSG00000056577 +258934 Olfr802 MGI:MGI:3030636|Ensembl:ENSMUSG00000093866|Vega:OTTMUSG00000056619 +258935 Olfr790 MGI:MGI:3030624|Ensembl:ENSMUSG00000044025|Vega:OTTMUSG00000056571 +258937 Olfr167 MGI:MGI:3030001|Ensembl:ENSMUSG00000045341|Vega:OTTMUSG00000058694 +258938 Olfr1417 MGI:MGI:3031251|Ensembl:ENSMUSG00000048292|Vega:OTTMUSG00000059429 +258939 Olfr63 MGI:MGI:1335096|Ensembl:ENSMUSG00000054666|Vega:OTTMUSG00000059245 +258940 Olfr346 MGI:MGI:3030180|Ensembl:ENSMUSG00000094764|Vega:OTTMUSG00000012205 +258941 Olfr354 MGI:MGI:3030188|Ensembl:ENSMUSG00000055088|Vega:OTTMUSG00000012215 +258942 Olfr352 MGI:MGI:3030186|Ensembl:ENSMUSG00000053146|Vega:OTTMUSG00000012231 +258943 Olfr353 MGI:MGI:3030187|Ensembl:ENSMUSG00000075382|Vega:OTTMUSG00000012212 +258944 Olfr351 MGI:MGI:3030185|Ensembl:ENSMUSG00000075383|Vega:OTTMUSG00000012223 +258945 Olfr347 MGI:MGI:3030181|Ensembl:ENSMUSG00000111863|Vega:OTTMUSG00000012209 +258946 Olfr348 MGI:MGI:3030182|Ensembl:ENSMUSG00000049315|Vega:OTTMUSG00000012208 +258947 Olfr345 MGI:MGI:3030179|Ensembl:ENSMUSG00000059251|Vega:OTTMUSG00000012214 +258949 Olfr338 MGI:MGI:3030172|Ensembl:ENSMUSG00000068950|Vega:OTTMUSG00000012143 +258950 Olfr342 MGI:MGI:3030176|Ensembl:ENSMUSG00000111869|Vega:OTTMUSG00000012218 +258951 Olfr339 MGI:MGI:3030173|Ensembl:ENSMUSG00000094464|Vega:OTTMUSG00000012139 +258952 Olfr341 MGI:MGI:3030175|Ensembl:ENSMUSG00000075387|Vega:OTTMUSG00000012217 +258953 Olfr340 MGI:MGI:3030174|Ensembl:ENSMUSG00000094266|Vega:OTTMUSG00000012138 +258954 Olfr522 MGI:MGI:3030356|Ensembl:ENSMUSG00000051180|Vega:OTTMUSG00000060574 +258955 Olfr531 MGI:MGI:3030365|Ensembl:ENSMUSG00000062712|Vega:OTTMUSG00000060475 +258956 Olfr535 MGI:MGI:3030369|Ensembl:ENSMUSG00000063230|Vega:OTTMUSG00000060479 +258958 Olfr525 MGI:MGI:3030359|Ensembl:ENSMUSG00000061489|Vega:OTTMUSG00000060580 +258959 Olfr170 MGI:MGI:3030004|Ensembl:ENSMUSG00000062245|Vega:OTTMUSG00000058762 +258960 Olfr171 MGI:MGI:3030005|Ensembl:ENSMUSG00000060480|Vega:OTTMUSG00000058763 +258961 Olfr631 MGI:MGI:3030465|Ensembl:ENSMUSG00000042219|Vega:OTTMUSG00000019069 +258962 Olfr53 MGI:MGI:1333749|Ensembl:ENSMUSG00000094819|Vega:OTTMUSG00000060427 +258963 Olfr539 MGI:MGI:3030373|Ensembl:ENSMUSG00000059136|Vega:OTTMUSG00000060428 +258964 Olfr541 MGI:MGI:3030375|Ensembl:ENSMUSG00000057997 +258967 Olfr1250 MGI:MGI:3031084|Ensembl:ENSMUSG00000075078|Vega:OTTMUSG00000014148 +258968 Olfr1247 MGI:MGI:3031081|Ensembl:ENSMUSG00000075081|Vega:OTTMUSG00000014150 +258969 Olfr1226 MGI:MGI:3031060|Ensembl:ENSMUSG00000075097|Vega:OTTMUSG00000014016 +258970 Olfr1242 MGI:MGI:3031076|Ensembl:ENSMUSG00000075085|Vega:OTTMUSG00000014147 +258971 Olfr1243 MGI:MGI:3031077|Ensembl:ENSMUSG00000075084|Vega:OTTMUSG00000014157 +258972 Olfr1239 MGI:MGI:3031073|Ensembl:ENSMUSG00000075088|Vega:OTTMUSG00000014149 +258973 Olfr1228 MGI:MGI:3031062|Ensembl:ENSMUSG00000099486|Vega:OTTMUSG00000014023 +258974 Olfr1233 MGI:MGI:3031067|Ensembl:ENSMUSG00000075091|Vega:OTTMUSG00000014152 +258975 Olfr1234 MGI:MGI:3031068|Ensembl:ENSMUSG00000075090|Vega:OTTMUSG00000014156 +258976 Olfr1262 MGI:MGI:3031096|Ensembl:ENSMUSG00000051313|Vega:OTTMUSG00000014231 +258977 Olfr1273-ps MGI:MGI:3031107|Ensembl:ENSMUSG00000080809|Vega:OTTMUSG00000014227 +258979 Olfr1255 MGI:MGI:3031089|Ensembl:ENSMUSG00000045148|Vega:OTTMUSG00000014239 +258980 Olfr1258 MGI:MGI:3031092|Ensembl:ENSMUSG00000049149|Vega:OTTMUSG00000014238 +258981 Olfr1268-ps1 MGI:MGI:3031102 +258982 Olfr1272 MGI:MGI:3031106|Ensembl:ENSMUSG00000075061|Vega:OTTMUSG00000014229 +258983 Olfr1260 MGI:MGI:3031094|Ensembl:ENSMUSG00000042894|Vega:OTTMUSG00000014241 +258984 Olfr1257 MGI:MGI:3031091|Ensembl:ENSMUSG00000049057|Vega:OTTMUSG00000014220 +258985 Olfr1256 MGI:MGI:3031090|Ensembl:ENSMUSG00000075073|Vega:OTTMUSG00000014228 +258986 Olfr4 MGI:MGI:106009 +258987 Olfr1270 MGI:MGI:3031104|Ensembl:ENSMUSG00000075065|Vega:OTTMUSG00000014226 +258988 Olfr38 MGI:MGI:1313140|Ensembl:ENSMUSG00000095236|Vega:OTTMUSG00000057455 +258989 Olfr457 MGI:MGI:3030291|Ensembl:ENSMUSG00000091983|Vega:OTTMUSG00000057382 +258990 Olfr447 MGI:MGI:3030281|Ensembl:ENSMUSG00000045708|Vega:OTTMUSG00000057460 +258991 Olfr1496 MGI:MGI:3031330|Ensembl:ENSMUSG00000048356|Vega:OTTMUSG00000059633 +258992 Olfr1494 MGI:MGI:3031328|Ensembl:ENSMUSG00000050865|Vega:OTTMUSG00000059631 +258993 Olfr206 MGI:MGI:3030040|Ensembl:ENSMUSG00000066257|Vega:OTTMUSG00000059133 +258994 Olfr204 MGI:MGI:3030038|Ensembl:ENSMUSG00000095928|Vega:OTTMUSG00000059131 +258995 Olfr176 MGI:MGI:3030010 +258996 Olfr201 MGI:MGI:3030035|Ensembl:ENSMUSG00000074995|Vega:OTTMUSG00000059129 +258997 Olfr202 MGI:MGI:3030036|Ensembl:ENSMUSG00000048810|Vega:OTTMUSG00000059130 +258998 Olfr177 MGI:MGI:3030011|Ensembl:ENSMUSG00000063137|Vega:OTTMUSG00000058831 +258999 Olfr178 MGI:MGI:3030012|Ensembl:ENSMUSG00000044029|Vega:OTTMUSG00000058832 +259000 Olfr195 MGI:MGI:3030029|Ensembl:ENSMUSG00000062608|Vega:OTTMUSG00000059123 +259001 Olfr181 MGI:MGI:3030015|Ensembl:ENSMUSG00000090951|Vega:OTTMUSG00000058834 +259002 Olfr173 MGI:MGI:3030007|Ensembl:ENSMUSG00000049362|Vega:OTTMUSG00000058829 +259003 Olfr172 MGI:MGI:3030006|Ensembl:ENSMUSG00000071510|Vega:OTTMUSG00000058828 +259004 Olfr175-ps1 MGI:MGI:3030009|Ensembl:ENSMUSG00000060663|Vega:OTTMUSG00000058830 +259005 Olfr139 MGI:MGI:2177522|Ensembl:ENSMUSG00000047444|Vega:OTTMUSG00000006161 +259006 Olfr399 MGI:MGI:3030233|Ensembl:ENSMUSG00000043692|Vega:OTTMUSG00000006162 +259007 Olfr395 MGI:MGI:3030229|Ensembl:ENSMUSG00000062186|Vega:OTTMUSG00000006155 +259008 Olfr392 MGI:MGI:3030226|Ensembl:ENSMUSG00000061984|Vega:OTTMUSG00000006151 +259009 Olfr394 MGI:MGI:3030228|Ensembl:ENSMUSG00000056921|Vega:OTTMUSG00000006154 +259010 Olfr393 MGI:MGI:3030227|Ensembl:ENSMUSG00000094488|Vega:OTTMUSG00000006153 +259011 Olfr389 MGI:MGI:3030223|Ensembl:ENSMUSG00000070383|Vega:OTTMUSG00000006148 +259012 Olfr1052 MGI:MGI:3030886|Ensembl:ENSMUSG00000047149|Vega:OTTMUSG00000013533 +259013 Olfr1044 MGI:MGI:3030878|Ensembl:ENSMUSG00000075200|Vega:OTTMUSG00000013654 +259014 Olfr1047 MGI:MGI:3030881|Ensembl:ENSMUSG00000075196|Vega:OTTMUSG00000013660 +259015 Olfr1038-ps MGI:MGI:3030872|Ensembl:ENSMUSG00000050577|Vega:OTTMUSG00000013640 +259016 Olfr1048 MGI:MGI:3030882|Ensembl:ENSMUSG00000075195|Vega:OTTMUSG00000013658 +259017 Olfr1019 MGI:MGI:3030853|Ensembl:ENSMUSG00000075208|Vega:OTTMUSG00000013590 +259018 Olfr1049 MGI:MGI:3030883|Ensembl:ENSMUSG00000075194|Vega:OTTMUSG00000013661 +259019 Olfr1045 MGI:MGI:3030879|Ensembl:ENSMUSG00000075198|Vega:OTTMUSG00000013663 +259020 Olfr1056 MGI:MGI:3030890|Ensembl:ENSMUSG00000075188|Vega:OTTMUSG00000013569 +259021 Olfr1054 MGI:MGI:3030888|Ensembl:ENSMUSG00000075190|Vega:OTTMUSG00000013531 +259022 Olfr1061 MGI:MGI:3030895|Ensembl:ENSMUSG00000075185|Vega:OTTMUSG00000013566 +259023 Olfr1055 MGI:MGI:3030889|Ensembl:ENSMUSG00000075189|Vega:OTTMUSG00000013537 +259024 Olfr381 MGI:MGI:3030215|Ensembl:ENSMUSG00000072708|Vega:OTTMUSG00000006138 +259025 Olfr385 MGI:MGI:3030219|Ensembl:ENSMUSG00000095095|Vega:OTTMUSG00000006141 +259026 Olfr378 MGI:MGI:3030212|Ensembl:ENSMUSG00000055971|Vega:OTTMUSG00000006135 +259027 Olfr380 MGI:MGI:3030214|Ensembl:ENSMUSG00000072709|Vega:OTTMUSG00000006128 +259028 Olfr532 MGI:MGI:3030366|Ensembl:ENSMUSG00000063823|Vega:OTTMUSG00000060476 +259030 Olfr1124 MGI:MGI:3030958|Ensembl:ENSMUSG00000050772|Vega:OTTMUSG00000013789 +259031 Olfr1120 MGI:MGI:3030954|Ensembl:ENSMUSG00000081234|Vega:OTTMUSG00000013781 +259032 Olfr1134 MGI:MGI:3030968|Ensembl:ENSMUSG00000111747|Vega:OTTMUSG00000013841 +259033 Olfr1122 MGI:MGI:3030956|Ensembl:ENSMUSG00000047594|Vega:OTTMUSG00000013771 +259034 Olfr705 MGI:MGI:3030539|Ensembl:ENSMUSG00000109058|Vega:OTTMUSG00000059721 +259035 Olfr714 MGI:MGI:3030548|Ensembl:ENSMUSG00000049674|Vega:OTTMUSG00000059734 +259036 Olfr713 MGI:MGI:3030547|Ensembl:ENSMUSG00000073898|Vega:OTTMUSG00000059732 +259037 Olfr711 MGI:MGI:3030545|Ensembl:ENSMUSG00000045013|Vega:OTTMUSG00000059729 +259038 Olfr283 MGI:MGI:3030117|Ensembl:ENSMUSG00000056184|Vega:OTTMUSG00000058680 +259039 Olfr1413 MGI:MGI:3031247|Ensembl:ENSMUSG00000058904|Vega:OTTMUSG00000048563 +259040 Olfr1416 MGI:MGI:3031250|Ensembl:ENSMUSG00000067064|Vega:OTTMUSG00000048560 +259041 Olfr1414 MGI:MGI:3031248|Ensembl:ENSMUSG00000042849|Vega:OTTMUSG00000048562 +259042 Olfr1351 MGI:MGI:3031185|Ensembl:ENSMUSG00000063216|Vega:OTTMUSG00000056729 +259044 Olfr1353 MGI:MGI:3031187|Ensembl:ENSMUSG00000042774|Vega:OTTMUSG00000056728 +259045 Olfr669 MGI:MGI:3030503|Ensembl:ENSMUSG00000073916|Vega:OTTMUSG00000060549 +259046 Olfr679 MGI:MGI:3030513|Ensembl:ENSMUSG00000096029|Vega:OTTMUSG00000060645 +259047 Olfr683 MGI:MGI:3030517|Ensembl:ENSMUSG00000044120|Vega:OTTMUSG00000060648 +259048 Olfr600 MGI:MGI:3030434|Ensembl:ENSMUSG00000045540|Vega:OTTMUSG00000019072 +259049 Olfr618 MGI:MGI:3030452|Ensembl:ENSMUSG00000073945|Vega:OTTMUSG00000019043 +259050 Olfr652 MGI:MGI:3030486|Ensembl:ENSMUSG00000073927|Vega:OTTMUSG00000019189 +259051 Olfr658 MGI:MGI:3030492|Ensembl:ENSMUSG00000070421|Vega:OTTMUSG00000019198 +259052 Olfr659 MGI:MGI:3030493|Ensembl:ENSMUSG00000073922|Vega:OTTMUSG00000019185 +259053 Olfr362 MGI:MGI:3030196|Ensembl:ENSMUSG00000075377|Vega:OTTMUSG00000012207 +259054 Olfr589 MGI:MGI:3030423|Ensembl:ENSMUSG00000051362|Vega:OTTMUSG00000019028 +259055 Olfr582 MGI:MGI:3030416|Ensembl:ENSMUSG00000073961|Vega:OTTMUSG00000060210 +259056 Olfr584 MGI:MGI:3030418|Ensembl:ENSMUSG00000073959|Vega:OTTMUSG00000019064 +259057 Olfr649 MGI:MGI:3030483|Ensembl:ENSMUSG00000044899|Vega:OTTMUSG00000019100 +259058 Olfr646 MGI:MGI:3030480|Ensembl:ENSMUSG00000073931|Vega:OTTMUSG00000019022 +259061 Olfr668 MGI:MGI:3030502|Ensembl:ENSMUSG00000057770|Vega:OTTMUSG00000060548 +259062 Olfr667 MGI:MGI:3030501|Ensembl:ENSMUSG00000056782|Vega:OTTMUSG00000060547 +259063 Olfr691 MGI:MGI:3030525|Ensembl:ENSMUSG00000043948|Vega:OTTMUSG00000060492 +259064 Olfr124 MGI:MGI:2177507|Ensembl:ENSMUSG00000044985|Vega:OTTMUSG00000037475 +259066 Olfr520 MGI:MGI:3030354|Ensembl:ENSMUSG00000073998|Vega:OTTMUSG00000059109 +259067 Olfr449 MGI:MGI:3030283|Ensembl:ENSMUSG00000049168|Vega:OTTMUSG00000057458 +259068 Olfr1390 MGI:MGI:3031224|Ensembl:ENSMUSG00000045421|Vega:OTTMUSG00000005548 +259069 Olfr1389 MGI:MGI:3031223|Ensembl:ENSMUSG00000107573|Vega:OTTMUSG00000005551 +259070 Olfr829 MGI:MGI:3030663|Ensembl:ENSMUSG00000051414|Vega:OTTMUSG00000061149 +259071 Olfr166 MGI:MGI:3030000|Ensembl:ENSMUSG00000056822|Vega:OTTMUSG00000058693 +259072 Olfr686 MGI:MGI:3030520|Ensembl:ENSMUSG00000048425|Vega:OTTMUSG00000060651 +259073 Olfr603 MGI:MGI:3030437|Ensembl:ENSMUSG00000059874|Vega:OTTMUSG00000022557 +259074 Olfr1352 MGI:MGI:3031186|Ensembl:ENSMUSG00000046493|Vega:OTTMUSG00000056766 +259075 Olfr641 MGI:MGI:3030475|Ensembl:ENSMUSG00000073932|Vega:OTTMUSG00000019086 +259078 Olfr656 MGI:MGI:3030490|Ensembl:ENSMUSG00000073924|Vega:OTTMUSG00000019178 +259080 Olfr619 MGI:MGI:3030453|Ensembl:ENSMUSG00000073944|Vega:OTTMUSG00000019048 +259081 Olfr643 MGI:MGI:3030477|Ensembl:ENSMUSG00000090219|Ensembl:ENSMUSG00000109824|Vega:OTTMUSG00000019023 +259082 Olfr1062 MGI:MGI:3030896|Ensembl:ENSMUSG00000090059|Vega:OTTMUSG00000013614 +259083 Olfr547 MGI:MGI:3030381|Ensembl:ENSMUSG00000073979|Vega:OTTMUSG00000060015 +259084 Olfr615 MGI:MGI:3030449|Ensembl:ENSMUSG00000073947|Vega:OTTMUSG00000019092 +259085 Olfr610 MGI:MGI:3030444|Ensembl:ENSMUSG00000045584|Vega:OTTMUSG00000019080 +259086 Olfr609 MGI:MGI:3030443|Ensembl:ENSMUSG00000046396|Vega:OTTMUSG00000019027 +259087 Olfr622 MGI:MGI:3030456|Ensembl:ENSMUSG00000050085|Vega:OTTMUSG00000019063 +259088 Olfr639 MGI:MGI:3030473|Ensembl:ENSMUSG00000066263|Vega:OTTMUSG00000019089 +259089 Olfr571 MGI:MGI:3030405|Ensembl:ENSMUSG00000043310|Vega:OTTMUSG00000060107 +259090 Olfr562-ps1 MGI:MGI:3030396 +259091 Olfr585 MGI:MGI:3030419|Ensembl:ENSMUSG00000078080|Vega:OTTMUSG00000019037 +259092 Olfr569 MGI:MGI:3030403|Ensembl:ENSMUSG00000062142|Vega:OTTMUSG00000060105 +259093 Olfr572 MGI:MGI:3030406|Ensembl:ENSMUSG00000073963|Vega:OTTMUSG00000060108 +259094 Olfr588-ps1 MGI:MGI:3030422 +259095 Olfr568 MGI:MGI:3030402|Ensembl:ENSMUSG00000073965|Vega:OTTMUSG00000060104 +259096 Olfr561 MGI:MGI:3030395|Ensembl:ENSMUSG00000073966|Vega:OTTMUSG00000060056 +259097 Olfr558 MGI:MGI:3030392|Ensembl:ENSMUSG00000070423|Vega:OTTMUSG00000060051 +259098 Olfr606 MGI:MGI:3030440|Ensembl:ENSMUSG00000073949|Vega:OTTMUSG00000019038 +259099 Olfr676 MGI:MGI:3030510|Ensembl:ENSMUSG00000073915|Vega:OTTMUSG00000060556 +259100 Olfr666 MGI:MGI:3030500|Ensembl:ENSMUSG00000063582|Vega:OTTMUSG00000060546 +259102 Olfr630 MGI:MGI:3030464|Ensembl:ENSMUSG00000050281|Vega:OTTMUSG00000019084 +259103 Olfr616 MGI:MGI:3030450|Ensembl:ENSMUSG00000047544|Vega:OTTMUSG00000019020 +259104 Olfr613 MGI:MGI:3030447|Ensembl:ENSMUSG00000078624|Vega:OTTMUSG00000019026 +259105 Olfr549 MGI:MGI:3030383|Ensembl:ENSMUSG00000073977|Vega:OTTMUSG00000060016 +259106 Olfr552 MGI:MGI:3030386|Ensembl:ENSMUSG00000073973|Vega:OTTMUSG00000060019 +259107 Olfr555 MGI:MGI:3030389|Ensembl:ENSMUSG00000073970|Vega:OTTMUSG00000060022 +259108 Olfr550 MGI:MGI:3030384|Ensembl:ENSMUSG00000073975|Vega:OTTMUSG00000060017 +259109 Olfr978 MGI:MGI:3030812|Ensembl:ENSMUSG00000044292|Vega:OTTMUSG00000062405 +259110 Olfr980 MGI:MGI:3030814|Ensembl:ENSMUSG00000060254|Vega:OTTMUSG00000062407 +259111 Olfr974 MGI:MGI:3030808|Ensembl:ENSMUSG00000051493|Vega:OTTMUSG00000062401 +259112 Olfr979 MGI:MGI:3030813|Ensembl:ENSMUSG00000059473|Vega:OTTMUSG00000062406 +259113 Olfr577 MGI:MGI:3030411|Ensembl:ENSMUSG00000043354|Vega:OTTMUSG00000060147 +259114 Olfr570 MGI:MGI:3030404|Ensembl:ENSMUSG00000073964|Vega:OTTMUSG00000060106 +259115 Olfr586 MGI:MGI:3030420|Ensembl:ENSMUSG00000066268|Vega:OTTMUSG00000019021 +259116 Olfr559 MGI:MGI:3030393|Ensembl:ENSMUSG00000066272|Vega:OTTMUSG00000060053 +259117 Olfr560 MGI:MGI:3030394|Ensembl:ENSMUSG00000110008|Vega:OTTMUSG00000060055 +259118 Olfr575 MGI:MGI:3030409|Ensembl:ENSMUSG00000066269|Vega:OTTMUSG00000060110 +259119 Olfr578 MGI:MGI:3030412|Ensembl:ENSMUSG00000045792|Vega:OTTMUSG00000060148 +259122 Olfr635 MGI:MGI:3030469|Ensembl:ENSMUSG00000094520|Vega:OTTMUSG00000019074 +259123 Olfr632 MGI:MGI:3030466|Ensembl:ENSMUSG00000073938|Vega:OTTMUSG00000019059 +259124 Olfr638 MGI:MGI:3030472|Ensembl:ENSMUSG00000094063|Vega:OTTMUSG00000019095 +259125 Olfr644 MGI:MGI:3030478|Ensembl:ENSMUSG00000110012|Vega:OTTMUSG00000019098 +259126 Olfr623 MGI:MGI:3030457|Ensembl:ENSMUSG00000099687|Vega:OTTMUSG00000019015 +259137 Olfr1556-ps1 MGI:MGI:3031390 +259138 Olfr200-ps1 MGI:MGI:3030034 +259140 Olfr1063-ps1 MGI:MGI:3030897 +259141 Olfr1544-ps1 MGI:MGI:3031378 +259142 Olfr1542-ps1 MGI:MGI:3031376 +259143 Olfr503 MGI:MGI:3030337|Ensembl:ENSMUSG00000060759|Vega:OTTMUSG00000059993 +259144 Olfr456 MGI:MGI:3030290|Ensembl:ENSMUSG00000090631|Vega:OTTMUSG00000022554 +259145 Olfr1251 MGI:MGI:3031085|Ensembl:ENSMUSG00000111567|Vega:OTTMUSG00000014145 +259147 Olfr723 MGI:MGI:3030557|Ensembl:ENSMUSG00000093825|Vega:OTTMUSG00000058464 +259148 Olfr329-ps MGI:MGI:3030163|Ensembl:ENSMUSG00000064252|Vega:OTTMUSG00000005745 +259151 Olfr1037 MGI:MGI:3030871|Ensembl:ENSMUSG00000075205|Vega:OTTMUSG00000013623 +259155 Olfr1528-ps1 MGI:MGI:3031362 +259157 Olfr563-ps1 MGI:MGI:3030397 +259158 Olfr1527-ps1 MGI:MGI:3031361 +259159 Olfr628 MGI:MGI:3030462|Ensembl:ENSMUSG00000096516|Vega:OTTMUSG00000019036 +259161 Olfr688 MGI:MGI:3030522|Ensembl:ENSMUSG00000073909|Vega:OTTMUSG00000060653 +259162 Olfr427 MGI:MGI:3030261|Ensembl:ENSMUSG00000059371|Vega:OTTMUSG00000050212 +259163 Olfr1354 MGI:MGI:3031188|Ensembl:ENSMUSG00000094673|Vega:OTTMUSG00000056726 +259165 Olfr814 MGI:MGI:3030648|Ensembl:ENSMUSG00000059134|Vega:OTTMUSG00000056631 +259172 Mfrp MGI:MGI:2385957|Ensembl:ENSMUSG00000034739|Vega:OTTMUSG00000033669 +259277 Klk8 MGI:MGI:1343327|Ensembl:ENSMUSG00000064023|Vega:OTTMUSG00000058312 +259279 Tubgcp3 MGI:MGI:2183752|Ensembl:ENSMUSG00000000759|Vega:OTTMUSG00000036064 +259280 Ap7q MGI:MGI:2155164 +259281 Ap8q MGI:MGI:2155165 +259300 Ehd2 MGI:MGI:2154274|Ensembl:ENSMUSG00000074364|Vega:OTTMUSG00000023141 +259301 Leap2 MGI:MGI:2672795|Ensembl:ENSMUSG00000036216|Vega:OTTMUSG00000000052 +259302 Srgap3 MGI:MGI:2152938|Ensembl:ENSMUSG00000030257|Vega:OTTMUSG00000022682 +260296 Trim61 MGI:MGI:2387432|Ensembl:ENSMUSG00000109718|Vega:OTTMUSG00000061286 +260297 Prrt1 MGI:MGI:1932118|Ensembl:ENSMUSG00000015476|Vega:OTTMUSG00000018397 +260298 Fev MGI:MGI:2449712|Ensembl:ENSMUSG00000055197|Vega:OTTMUSG00000034755 +260299 Cadm4 MGI:MGI:2449088|Ensembl:ENSMUSG00000054793|Vega:OTTMUSG00000017136 +260300 Gm1549 MGI:MGI:2686395 +260301 Otos MGI:MGI:2672814|Ensembl:ENSMUSG00000044055|Vega:OTTMUSG00000034772 +260302 Gga3 MGI:MGI:2384159|Ensembl:ENSMUSG00000020740|Vega:OTTMUSG00000003472 +260305 Nphp4 MGI:MGI:2384210|Ensembl:ENSMUSG00000039577|Vega:OTTMUSG00000010703 +260315 Nav3 MGI:MGI:2183703|Ensembl:ENSMUSG00000020181|Vega:OTTMUSG00000034560 +260344 Phf5b-ps MGI:MGI:2156868 +260346 Gm5036 MGI:MGI:3648479 +260347 Gm5037 MGI:MGI:3648478 +260348 Gm12222 MGI:MGI:3649523 +260396 Pain1 MGI:MGI:2384610 +260397 Sials MGI:MGI:2384611 +260398 Thypr2 MGI:MGI:2384613 +260399 Thypr3 MGI:MGI:2384614 +260400 Thypr1 MGI:MGI:2384612 +260401 Eae26 MGI:MGI:2384617 +260408 Prss45 MGI:MGI:3605764|Ensembl:ENSMUSG00000047257|Vega:OTTMUSG00000034119 +260409 Cdc42ep3 MGI:MGI:2384718|Ensembl:ENSMUSG00000036533 +260411 Desp1 MGI:MGI:2385356 +260412 Desp2 MGI:MGI:2385357 +260413 Fubi1 MGI:MGI:2385337 +260418 Bcmd2 MGI:MGI:2385436 +260419 Acsns1 MGI:MGI:2385458 +260423 Hist1h3f MGI:MGI:2448329|Ensembl:ENSMUSG00000100210|Vega:OTTMUSG00000000572 +263305 Gm5038 MGI:MGI:3645262 +263406 Plekhg3 MGI:MGI:2388284|Ensembl:ENSMUSG00000052609 +263764 Creg2 MGI:MGI:1928333|Ensembl:ENSMUSG00000050967|Vega:OTTMUSG00000049490 +263803 Pkn3 MGI:MGI:2388285|Ensembl:ENSMUSG00000026785|Vega:OTTMUSG00000016746 +263876 Spata2 MGI:MGI:2146885|Ensembl:ENSMUSG00000047030|Vega:OTTMUSG00000001142 +264064 Cdk8 MGI:MGI:1196224|Ensembl:ENSMUSG00000029635|Vega:OTTMUSG00000025856 +264134 Ttc26 MGI:MGI:2444853|Ensembl:ENSMUSG00000056832|Vega:OTTMUSG00000034251 +264895 Acsf2 MGI:MGI:2388287|Ensembl:ENSMUSG00000076435|Vega:OTTMUSG00000002019 +266459 Gm5039 MGI:MGI:3648085 +266614 Ly6g5b MGI:MGI:2385809|Ensembl:ENSMUSG00000043807|Vega:OTTMUSG00000037174 +266615 Svet1 MGI:MGI:2385655 +266620 Defb36 MGI:MGI:2385956|Ensembl:ENSMUSG00000044863|Vega:OTTMUSG00000015849 +266632 Irak4 MGI:MGI:2182474|Ensembl:ENSMUSG00000059883|Vega:OTTMUSG00000016696 +266645 Acmsd MGI:MGI:2386323|Ensembl:ENSMUSG00000026348|Vega:OTTMUSG00000049346 +266690 Cyb5r4 MGI:MGI:2386848|Ensembl:ENSMUSG00000032872|Vega:OTTMUSG00000037524 +266692 Cpne1 MGI:MGI:2386621|Ensembl:ENSMUSG00000074643|Vega:OTTMUSG00000019746 +266744 Lgsn MGI:MGI:2672844|Ensembl:ENSMUSG00000050217|Vega:OTTMUSG00000026558 +266781 Snx17 MGI:MGI:2387801|Ensembl:ENSMUSG00000029146|Vega:OTTMUSG00000022491 +266793 Snord87 MGI:MGI:2387894|Ensembl:ENSMUSG00000093178 +266815 Mill1 MGI:MGI:2179988|Ensembl:ENSMUSG00000054005|Vega:OTTMUSG00000017115 +267019 Rps15a MGI:MGI:2389091|Ensembl:ENSMUSG00000008683|Vega:OTTMUSG00000023996 +268281 Shprh MGI:MGI:1917581|Ensembl:ENSMUSG00000090112|Vega:OTTMUSG00000034163 +268288 Samd3 MGI:MGI:2685469|Ensembl:ENSMUSG00000051354 +268291 Rnf217 MGI:MGI:3610311|Ensembl:ENSMUSG00000063760|Vega:OTTMUSG00000039901 +268294 Zbtb24 MGI:MGI:3039618|Ensembl:ENSMUSG00000019826|Vega:OTTMUSG00000063445 +268297 Scml4 MGI:MGI:2446140|Ensembl:ENSMUSG00000044770|Vega:OTTMUSG00000017273 +268300 Gm5040 MGI:MGI:3648144 +268301 Sowahc MGI:MGI:3606051|Ensembl:ENSMUSG00000098188|Vega:OTTMUSG00000044376 +268307 4833431D13Rik MGI:MGI:3036232 +268319 BC025920 MGI:MGI:2670983|Ensembl:ENSMUSG00000074862|Vega:OTTMUSG00000030462 +268345 Kcnc2 MGI:MGI:96668|Ensembl:ENSMUSG00000035681 +268354 Fam19a2 MGI:MGI:2143691|Ensembl:ENSMUSG00000044071 +268373 Ppia MGI:MGI:97749|Ensembl:ENSMUSG00000071866|Vega:OTTMUSG00000000783 +268379 Abca13 MGI:MGI:2388707|Ensembl:ENSMUSG00000004668|Vega:OTTMUSG00000005151 +268390 Ahsa2 MGI:MGI:1916133|Ensembl:ENSMUSG00000020288|Vega:OTTMUSG00000005278 +268391 A830031A19Rik MGI:MGI:2685508 +268395 Mpg MGI:MGI:97073|Ensembl:ENSMUSG00000020287|Vega:OTTMUSG00000005371 +268396 Sh3pxd2b MGI:MGI:2442062|Ensembl:ENSMUSG00000040711|Vega:OTTMUSG00000005375 +268417 Zkscan17 MGI:MGI:2679270|Ensembl:ENSMUSG00000020472|Vega:OTTMUSG00000005796 +268420 Alkbh5 MGI:MGI:2144489|Ensembl:ENSMUSG00000042650|Vega:OTTMUSG00000007765 +268445 Ankrd13b MGI:MGI:2144501|Ensembl:ENSMUSG00000037907|Vega:OTTMUSG00000008176 +268448 Phf12 MGI:MGI:1924057|Ensembl:ENSMUSG00000037791|Vega:OTTMUSG00000000069 +268449 Rpl23a MGI:MGI:3040672|Ensembl:ENSMUSG00000058546|Vega:OTTMUSG00000000095 +268451 Rab11fip4 MGI:MGI:2442920|Ensembl:ENSMUSG00000017639|Vega:OTTMUSG00000000184 +268465 Eme1 MGI:MGI:3576783|Ensembl:ENSMUSG00000039055|Vega:OTTMUSG00000002020 +268469 Zfp652 MGI:MGI:2442221|Ensembl:ENSMUSG00000075595|Vega:OTTMUSG00000001747 +268470 Ube2z MGI:MGI:1343160|Ensembl:ENSMUSG00000014349|Vega:OTTMUSG00000001958 +268480 Rapgefl1 MGI:MGI:3611446|Ensembl:ENSMUSG00000038020|Vega:OTTMUSG00000006452 +268481 Krt222 MGI:MGI:2442728|Ensembl:ENSMUSG00000035849|Vega:OTTMUSG00000006442 +268482 Krt12 MGI:MGI:96687|Ensembl:ENSMUSG00000020912|Vega:OTTMUSG00000004989 +268490 Lsm12 MGI:MGI:1919592|Ensembl:ENSMUSG00000020922|Vega:OTTMUSG00000002494 +268491 Meioc MGI:MGI:2686410|Ensembl:ENSMUSG00000051455|Vega:OTTMUSG00000002948 +268498 E030025P04Rik MGI:MGI:2685510|Ensembl:ENSMUSG00000078605|Vega:OTTMUSG00000003136 +268510 Mgat5b MGI:MGI:3606200|Ensembl:ENSMUSG00000043857|Vega:OTTMUSG00000003786 +268512 Slc26a11 MGI:MGI:2444589|Ensembl:ENSMUSG00000039908|Vega:OTTMUSG00000003912 +268515 Bahcc1 MGI:MGI:2679272|Ensembl:ENSMUSG00000039741|Vega:OTTMUSG00000004133 +268527 Greb1 MGI:MGI:2149712|Ensembl:ENSMUSG00000036523|Vega:OTTMUSG00000032970 +268534 Sntg2 MGI:MGI:1919541|Ensembl:ENSMUSG00000020672|Vega:OTTMUSG00000024421 +268564 Zbtb1 MGI:MGI:2442326|Ensembl:ENSMUSG00000033454|Vega:OTTMUSG00000034943 +268566 Gphn MGI:MGI:109602|Ensembl:ENSMUSG00000047454 +268567 Tmem229b MGI:MGI:2444389|Ensembl:ENSMUSG00000046157|Vega:OTTMUSG00000037736 +268591 Serpina5 MGI:MGI:107817|Ensembl:ENSMUSG00000041550|Vega:OTTMUSG00000035419 +268595 D430019H16Rik MGI:MGI:2443127|Ensembl:ENSMUSG00000094910|Vega:OTTMUSG00000060463 +268650 Rps17-ps1 MGI:MGI:3647979 +268656 Sptlc1 MGI:MGI:1099431|Ensembl:ENSMUSG00000021468 +268663 Cdhr2 MGI:MGI:2687323|Ensembl:ENSMUSG00000034918|Vega:OTTMUSG00000032682 +268670 Zfp759 MGI:MGI:2446280|Ensembl:ENSMUSG00000057396 +268676 Gm5042 MGI:MGI:3647790 +268686 S100z MGI:MGI:2685471|Ensembl:ENSMUSG00000021679 +268697 Ccnb1 MGI:MGI:88302|Ensembl:ENSMUSG00000041431|Vega:OTTMUSG00000020969 +268706 Slc38a9 MGI:MGI:1918839|Ensembl:ENSMUSG00000047789 +268709 Fam107a MGI:MGI:3041256|Ensembl:ENSMUSG00000021750|Vega:OTTMUSG00000027765 +268721 Zswim8 MGI:MGI:1919156|Ensembl:ENSMUSG00000021819 +268723 A830039N20Rik MGI:MGI:2445176 +268729 Frmpd2 MGI:MGI:2685472|Ensembl:ENSMUSG00000108841|Vega:OTTMUSG00000059341 +268739 Arhgef40 MGI:MGI:2685515|Ensembl:ENSMUSG00000004562|Vega:OTTMUSG00000043548 +268741 Tox4 MGI:MGI:1915389|Ensembl:ENSMUSG00000016831|Vega:OTTMUSG00000017450 +268747 Carmil3 MGI:MGI:2448573|Ensembl:ENSMUSG00000022211 +268749 Rnf31 MGI:MGI:1934704|Ensembl:ENSMUSG00000047098|Vega:OTTMUSG00000029026 +268752 Wdfy2 MGI:MGI:2442811|Ensembl:ENSMUSG00000014547 +268755 Mir124a-1hg MGI:MGI:2442197|Ensembl:ENSMUSG00000097545 +268756 Gulo MGI:MGI:1353434|Ensembl:ENSMUSG00000034450 +268759 9930012K11Rik MGI:MGI:2145726|Ensembl:ENSMUSG00000044551|Vega:OTTMUSG00000032872 +268780 Egflam MGI:MGI:2146149|Ensembl:ENSMUSG00000042961|Vega:OTTMUSG00000029264 +268781 Gm5043 MGI:MGI:3646551 +268782 Agxt2 MGI:MGI:2146052|Ensembl:ENSMUSG00000089678|Vega:OTTMUSG00000024223 +268783 Mtmr12 MGI:MGI:2443034|Ensembl:ENSMUSG00000039458|Vega:OTTMUSG00000037061 +268795 Rpl7a-ps3 MGI:MGI:3643413 +268807 Klhl38 MGI:MGI:3045310|Ensembl:ENSMUSG00000022357|Vega:OTTMUSG00000028041 +268809 Gm5045 MGI:MGI:3647181 +268812 Gm5046 MGI:MGI:3649048 +268816 Mroh5 MGI:MGI:2685474|Ensembl:ENSMUSG00000072487|Vega:OTTMUSG00000028047 +268822 Adck5 MGI:MGI:2679274|Ensembl:ENSMUSG00000022550|Vega:OTTMUSG00000034304 +268853 Gm671 MGI:MGI:2685517 +268857 Nlrc3 MGI:MGI:2444070|Ensembl:ENSMUSG00000049871|Vega:OTTMUSG00000042324 +268859 Rbfox1 MGI:MGI:1926224|Ensembl:ENSMUSG00000008658 +268860 Abat MGI:MGI:2443582|Ensembl:ENSMUSG00000057880|Vega:OTTMUSG00000025937 +268878 Atp13a5 MGI:MGI:2444068|Ensembl:ENSMUSG00000048939|Vega:OTTMUSG00000025882 +268880 Xxylt1 MGI:MGI:2146443|Ensembl:ENSMUSG00000047434|Vega:OTTMUSG00000026183 +268882 Fbxo45 MGI:MGI:2447775|Ensembl:ENSMUSG00000035764|Vega:OTTMUSG00000025766 +268885 Stfa2l1 MGI:MGI:3524944|Ensembl:ENSMUSG00000059657 +268890 Lsamp MGI:MGI:1261760|Ensembl:ENSMUSG00000061080|Vega:OTTMUSG00000016989 +268902 Robo2 MGI:MGI:1890110|Ensembl:ENSMUSG00000052516|Vega:OTTMUSG00000017043 +268903 Nrip1 MGI:MGI:1315213|Ensembl:ENSMUSG00000048490|Vega:OTTMUSG00000026674 +268905 Krtap13-1 MGI:MGI:2146359|Ensembl:ENSMUSG00000056350 +268930 Pkmyt1 MGI:MGI:2137630|Ensembl:ENSMUSG00000023908 +268932 Caskin1 MGI:MGI:2442952|Ensembl:ENSMUSG00000033597 +268933 Wdr24 MGI:MGI:2446285|Ensembl:ENSMUSG00000025737|Vega:OTTMUSG00000029399 +268934 Grm4 MGI:MGI:1351341|Ensembl:ENSMUSG00000063239|Vega:OTTMUSG00000028925 +268935 Scube3 MGI:MGI:3045253|Ensembl:ENSMUSG00000038677|Vega:OTTMUSG00000021032 +268936 Brpf3 MGI:MGI:2146836|Ensembl:ENSMUSG00000063952|Vega:OTTMUSG00000017315 +268949 Dpcr1 MGI:MGI:2685476|Ensembl:ENSMUSG00000073408|Vega:OTTMUSG00000037248 +268958 Capn11 MGI:MGI:1352490|Ensembl:ENSMUSG00000058626|Vega:OTTMUSG00000031350 +268970 Arhgap28 MGI:MGI:2147003|Ensembl:ENSMUSG00000024043|Vega:OTTMUSG00000035732 +268973 Nlrc4 MGI:MGI:3036243|Ensembl:ENSMUSG00000039193 +268977 Ltbp1 MGI:MGI:109151|Ensembl:ENSMUSG00000001870|Vega:OTTMUSG00000020204 +268980 Strn MGI:MGI:1333757|Ensembl:ENSMUSG00000024077|Vega:OTTMUSG00000024691 +268988 Gm5047 MGI:MGI:3645969 +268996 Ss18 MGI:MGI:107708|Ensembl:ENSMUSG00000037013 +269003 Sap130 MGI:MGI:1919782|Ensembl:ENSMUSG00000024260 +269016 Sh3rf2 MGI:MGI:2444628|Ensembl:ENSMUSG00000057719|Vega:OTTMUSG00000028094 +269019 Stk32a MGI:MGI:2442403|Ensembl:ENSMUSG00000039954 +269023 Zfp608 MGI:MGI:2442338|Ensembl:ENSMUSG00000052713 +269033 4930503L19Rik MGI:MGI:1922045|Ensembl:ENSMUSG00000044906|Vega:OTTMUSG00000061902 +269037 Ctif MGI:MGI:2685518|Ensembl:ENSMUSG00000052928 +269053 Gpr152 MGI:MGI:2685519|Ensembl:ENSMUSG00000044724 +269060 Dagla MGI:MGI:2677061|Ensembl:ENSMUSG00000035735|Vega:OTTMUSG00000021192 +269061 Cpsf7 MGI:MGI:1917826|Ensembl:ENSMUSG00000034820 +269063 Ms4a5 MGI:MGI:2670985|Ensembl:ENSMUSG00000054523|Vega:OTTMUSG00000047087 +269094 D730002M21Rik MGI:MGI:3041200 +269105 Gm5048 MGI:MGI:3642999 +269109 Dpp10 MGI:MGI:2442409|Ensembl:ENSMUSG00000036815|Vega:OTTMUSG00000020794 +269113 Nup54 MGI:MGI:1920460|Ensembl:ENSMUSG00000034826|Vega:OTTMUSG00000028742 +269116 Nfasc MGI:MGI:104753|Ensembl:ENSMUSG00000026442|Vega:OTTMUSG00000049394 +269120 Optc MGI:MGI:2151113|Ensembl:ENSMUSG00000010311|Vega:OTTMUSG00000026873 +269132 Colgalt2 MGI:MGI:2138232|Ensembl:ENSMUSG00000032649|Vega:OTTMUSG00000024393 +269134 Gm5049 MGI:MGI:3645970 +269152 Kif26b MGI:MGI:2447076|Ensembl:ENSMUSG00000026494|Vega:OTTMUSG00000034866 +269180 Inpp4a MGI:MGI:1931123|Ensembl:ENSMUSG00000026113|Vega:OTTMUSG00000033181 +269181 Mgat4a MGI:MGI:2662992|Ensembl:ENSMUSG00000026110|Vega:OTTMUSG00000033899 +269198 Nbeal1 MGI:MGI:2444343|Ensembl:ENSMUSG00000073664|Vega:OTTMUSG00000034193 +269202 BC019684 MGI:MGI:2652857 +269204 A730034C02 - +269209 Stk36 MGI:MGI:1920831|Ensembl:ENSMUSG00000033276|Vega:OTTMUSG00000021747 +269211 BC035947 MGI:MGI:2652858 +269224 Pask MGI:MGI:2155936|Ensembl:ENSMUSG00000026274|Vega:OTTMUSG00000021792 +269233 Fam171a1 MGI:MGI:2442917|Ensembl:ENSMUSG00000050530|Vega:OTTMUSG00000010785 +269252 Gtf3c4 MGI:MGI:2138937|Ensembl:ENSMUSG00000035666|Vega:OTTMUSG00000011769 +269254 Setx MGI:MGI:2443480|Ensembl:ENSMUSG00000043535|Vega:OTTMUSG00000011825 +269261 Rpl12 MGI:MGI:98002|Ensembl:ENSMUSG00000038900|Vega:OTTMUSG00000012575 +269275 Acvr1c MGI:MGI:2661081|Ensembl:ENSMUSG00000026834|Vega:OTTMUSG00000012673 +269292 Gm13676 MGI:MGI:3649533 +269295 Rtn4rl2 MGI:MGI:2669796|Ensembl:ENSMUSG00000050896|Vega:OTTMUSG00000013729 +269328 Muc15 MGI:MGI:2442110|Ensembl:ENSMUSG00000050808|Vega:OTTMUSG00000015151 +269336 Ccdc32 MGI:MGI:2685477|Ensembl:ENSMUSG00000039983|Vega:OTTMUSG00000015768 +269338 Vps39 MGI:MGI:2443189|Ensembl:ENSMUSG00000027291|Vega:OTTMUSG00000015284 +269344 Ell3 MGI:MGI:2673679|Ensembl:ENSMUSG00000027246|Vega:OTTMUSG00000015326 +269346 Slc28a2 MGI:MGI:1913105|Ensembl:ENSMUSG00000027219|Vega:OTTMUSG00000015614 +269356 Slc4a11 MGI:MGI:2138987|Ensembl:ENSMUSG00000074796|Vega:OTTMUSG00000015523 +269365 Rps19-ps7 MGI:MGI:3652235 +269378 Ahcy MGI:MGI:87968|Ensembl:ENSMUSG00000027597|Vega:OTTMUSG00000016006 +269389 Tox2 MGI:MGI:3611233|Ensembl:ENSMUSG00000074607|Vega:OTTMUSG00000001185 +269397 Ss18l1 MGI:MGI:2444061|Ensembl:ENSMUSG00000039086|Vega:OTTMUSG00000016229 +269400 Rtel1 MGI:MGI:2139369|Ensembl:ENSMUSG00000038685|Vega:OTTMUSG00000016649 +269401 Zfp512b MGI:MGI:2685478|Ensembl:ENSMUSG00000000823|Vega:OTTMUSG00000016738 +269423 Abhd18 MGI:MGI:1915468|Ensembl:ENSMUSG00000037818|Vega:OTTMUSG00000034285 +269424 Jade1 MGI:MGI:1925835|Ensembl:ENSMUSG00000025764|Vega:OTTMUSG00000051244 +269437 Plch1 MGI:MGI:2683547|Ensembl:ENSMUSG00000036834|Vega:OTTMUSG00000030810 +269470 Wdr3 MGI:MGI:2443143|Ensembl:ENSMUSG00000033285|Vega:OTTMUSG00000006955 +269472 LOC269472 - +269473 Lrig2 MGI:MGI:2443718|Ensembl:ENSMUSG00000032913|Vega:OTTMUSG00000054008 +269513 Nkain3 MGI:MGI:2444830|Ensembl:ENSMUSG00000055761|Vega:OTTMUSG00000004653 +269514 Fbxl4 MGI:MGI:2140367|Ensembl:ENSMUSG00000040410|Vega:OTTMUSG00000004757 +269523 Vcp MGI:MGI:99919|Ensembl:ENSMUSG00000028452|Vega:OTTMUSG00000006688 +269529 Fbxo10 MGI:MGI:2686937|Ensembl:ENSMUSG00000048232|Vega:OTTMUSG00000007455 +269536 Tex10 MGI:MGI:1344413|Ensembl:ENSMUSG00000028345|Vega:OTTMUSG00000006845 +269553 Mrpl48-ps MGI:MGI:3050089 +269569 Gm12728 MGI:MGI:3649486 +269582 Clspn MGI:MGI:2445153|Ensembl:ENSMUSG00000042489|Vega:OTTMUSG00000009280 +269585 Zscan20 MGI:MGI:2679268|Ensembl:ENSMUSG00000061894|Vega:OTTMUSG00000009454 +269587 Epb41 MGI:MGI:95401|Ensembl:ENSMUSG00000028906|Vega:OTTMUSG00000009743 +269589 Sytl1 MGI:MGI:1933365|Ensembl:ENSMUSG00000028860|Vega:OTTMUSG00000010476 +269593 Luzp1 MGI:MGI:107629|Ensembl:ENSMUSG00000001089|Vega:OTTMUSG00000009704 +269604 Gpr157 MGI:MGI:2442046|Ensembl:ENSMUSG00000047875|Vega:OTTMUSG00000010392 +269608 Plekhg5 MGI:MGI:2652860|Ensembl:ENSMUSG00000039713|Vega:OTTMUSG00000010225 +269610 Chd5 MGI:MGI:3036258|Ensembl:ENSMUSG00000005045|Vega:OTTMUSG00000010576 +269614 Pank4 MGI:MGI:2387466|Ensembl:ENSMUSG00000029056|Vega:OTTMUSG00000010467 +269615 Plch2 MGI:MGI:2443078|Ensembl:ENSMUSG00000029055|Vega:OTTMUSG00000010462 +269623 Rbm48 MGI:MGI:2442653|Ensembl:ENSMUSG00000040302|Vega:OTTMUSG00000028541 +269629 Lhfpl3 MGI:MGI:1925076|Ensembl:ENSMUSG00000106379|Vega:OTTMUSG00000053482 +269630 5031425E22Rik MGI:MGI:1923227|Ensembl:ENSMUSG00000073147 +269633 Wdr86 MGI:MGI:1915466|Ensembl:ENSMUSG00000055235|Vega:OTTMUSG00000023533 +269637 Cnpy1 MGI:MGI:2442451|Ensembl:ENSMUSG00000044681|Vega:OTTMUSG00000029652 +269639 Zfp512 MGI:MGI:1917345|Ensembl:ENSMUSG00000062761|Vega:OTTMUSG00000055212 +269642 Nat8l MGI:MGI:2447776|Ensembl:ENSMUSG00000048142|Vega:OTTMUSG00000055711 +269643 Ppp2r2c MGI:MGI:2442660|Ensembl:ENSMUSG00000029120|Vega:OTTMUSG00000022772 +269682 Golga3 MGI:MGI:96958|Ensembl:ENSMUSG00000029502|Vega:OTTMUSG00000026197 +269683 E130006D01Rik MGI:MGI:2685527|Ensembl:ENSMUSG00000085271 +269693 Ccdc60 MGI:MGI:2141043|Ensembl:ENSMUSG00000043913|Vega:OTTMUSG00000014688 +269695 Rnft2 MGI:MGI:2442859|Ensembl:ENSMUSG00000032850|Vega:OTTMUSG00000028972 +269700 Hectd4 MGI:MGI:3647820|Ensembl:ENSMUSG00000042744|Vega:OTTMUSG00000026283 +269701 Wdr66 MGI:MGI:1918495|Ensembl:ENSMUSG00000029442|Vega:OTTMUSG00000026924 +269702 Mphosph9 MGI:MGI:2443138|Ensembl:ENSMUSG00000038126|Vega:OTTMUSG00000024385 +269704 Zfp664 MGI:MGI:2442505|Ensembl:ENSMUSG00000079215|Vega:OTTMUSG00000024512 +269713 Clip2 MGI:MGI:1313136|Ensembl:ENSMUSG00000063146|Vega:OTTMUSG00000055745 +269717 Orai2 MGI:MGI:2443195|Ensembl:ENSMUSG00000039747|Vega:OTTMUSG00000054379 +269718 Gm5050 MGI:MGI:3649091 +269723 BC030343 MGI:MGI:2679267 +269739 BC022713 MGI:MGI:2679266 +269774 Aak1 MGI:MGI:1098687|Ensembl:ENSMUSG00000057230|Vega:OTTMUSG00000024486 +269784 Cntn4 MGI:MGI:1095737|Ensembl:ENSMUSG00000064293|Vega:OTTMUSG00000024598 +269788 Lhfpl4 MGI:MGI:3057108|Ensembl:ENSMUSG00000042873|Vega:OTTMUSG00000034861 +269799 Clec4a1 MGI:MGI:3036291|Ensembl:ENSMUSG00000049037|Vega:OTTMUSG00000027029 +269800 Zfp384 MGI:MGI:2443203|Ensembl:ENSMUSG00000038346|Vega:OTTMUSG00000022893 +269810 Gm5051 MGI:MGI:3647306 +269823 Pon3 MGI:MGI:106686|Ensembl:ENSMUSG00000029759|Vega:OTTMUSG00000024087 +269831 Tspan12 MGI:MGI:1889818|Ensembl:ENSMUSG00000029669|Vega:OTTMUSG00000026887 +269846 Trbv31 MGI:MGI:98588|IMGT/GENE-DB:TRBV31 +269854 Nat14 MGI:MGI:3039561|Ensembl:ENSMUSG00000035285|Vega:OTTMUSG00000058583 +269855 Ssc5d MGI:MGI:3606211|Ensembl:ENSMUSG00000035279|Vega:OTTMUSG00000058585 +269859 Gm5052 MGI:MGI:3647769 +269862 Olfr1349 MGI:MGI:3031183|Ensembl:ENSMUSG00000048067|Vega:OTTMUSG00000060116 +269870 Zfp446 MGI:MGI:2442185|Ensembl:ENSMUSG00000033961|Vega:OTTMUSG00000023323 +269878 Megf8 MGI:MGI:2446294|Ensembl:ENSMUSG00000045039|Vega:OTTMUSG00000033805 +269881 Map3k10 MGI:MGI:1346879|Ensembl:ENSMUSG00000040390|Vega:OTTMUSG00000023963 +269902 Vmn2r57 MGI:MGI:3703084|Ensembl:ENSMUSG00000066537|Vega:OTTMUSG00000037960 +269921 Mrgprc1-ps MGI:MGI:3033136 +269941 Chsy1 MGI:MGI:2681120|Ensembl:ENSMUSG00000032640|Vega:OTTMUSG00000029829 +269951 Idh2 MGI:MGI:96414|Ensembl:ENSMUSG00000030541|Vega:OTTMUSG00000024961 +269952 Gdpgp1 MGI:MGI:2443429|Ensembl:ENSMUSG00000050973|Vega:OTTMUSG00000022918 +269954 Ttll13 MGI:MGI:1920845|Ensembl:ENSMUSG00000045467|Vega:OTTMUSG00000023153 +269955 Rccd1 MGI:MGI:2444156|Ensembl:ENSMUSG00000038930|Vega:OTTMUSG00000029013 +269959 Adamtsl3 MGI:MGI:3028499|Ensembl:ENSMUSG00000070469|Vega:OTTMUSG00000038092 +269966 Nup98 MGI:MGI:109404|Ensembl:ENSMUSG00000063550|Vega:OTTMUSG00000061195 +269980 Gm5053 MGI:MGI:3645491 +269994 Gsg1l MGI:MGI:2685483|Ensembl:ENSMUSG00000046182|Vega:OTTMUSG00000058205 +269997 Zfp747 MGI:MGI:2443581|Ensembl:ENSMUSG00000054381|Vega:OTTMUSG00000058504 +269999 Orai3 MGI:MGI:3039586|Ensembl:ENSMUSG00000043964|Vega:OTTMUSG00000031096 +270004 Foxi2 MGI:MGI:3028075|Ensembl:ENSMUSG00000048377|Vega:OTTMUSG00000060273 +270014 Stk29 - +270015 Gm5054 MGI:MGI:3649024 +270028 Fam155a MGI:MGI:2142765|Ensembl:ENSMUSG00000079157|Vega:OTTMUSG00000059845 +270035 Letm2 MGI:MGI:2444979|Ensembl:ENSMUSG00000037363|Vega:OTTMUSG00000060558 +270049 Galntl6 MGI:MGI:1913581|Ensembl:ENSMUSG00000096914|Vega:OTTMUSG00000027194 +270058 Map1s MGI:MGI:2443304|Ensembl:ENSMUSG00000019261|Vega:OTTMUSG00000061603 +270066 Slc35e1 MGI:MGI:2142403|Ensembl:ENSMUSG00000019731|Vega:OTTMUSG00000033880 +270076 Gcdh MGI:MGI:104541|Ensembl:ENSMUSG00000003809|Vega:OTTMUSG00000030024 +270084 Lpcat2 MGI:MGI:3606214|Ensembl:ENSMUSG00000033192|Vega:OTTMUSG00000024681 +270086 Ogfod1 MGI:MGI:2442978|Ensembl:ENSMUSG00000033009|Vega:OTTMUSG00000023230 +270091 Lrrc36 MGI:MGI:2448585|Ensembl:ENSMUSG00000054320|Vega:OTTMUSG00000023050 +270096 Mon1b MGI:MGI:1923231|Ensembl:ENSMUSG00000078908|Vega:OTTMUSG00000061746 +270097 Vat1l MGI:MGI:2142534|Ensembl:ENSMUSG00000046844|Vega:OTTMUSG00000031710 +270106 Rpl13 MGI:MGI:105922|Ensembl:ENSMUSG00000000740|Vega:OTTMUSG00000016486 +270109 Pcnx2 MGI:MGI:2445010|Ensembl:ENSMUSG00000060212|Vega:OTTMUSG00000030588 +270110 Irf2bp2 MGI:MGI:2443921|Ensembl:ENSMUSG00000051495|Vega:OTTMUSG00000044607 +270118 Maml2 MGI:MGI:2389460|Ensembl:ENSMUSG00000031925|Vega:OTTMUSG00000033178 +270120 Fat3 MGI:MGI:2444314|Ensembl:ENSMUSG00000074505|Vega:OTTMUSG00000062421 +270148 Gm5055 MGI:MGI:3645061 +270150 Ccdc153 MGI:MGI:2448587|Ensembl:ENSMUSG00000070306|Vega:OTTMUSG00000063213 +270151 Nlrx1 MGI:MGI:2429611|Ensembl:ENSMUSG00000032109|Vega:OTTMUSG00000063221 +270152 Jaml MGI:MGI:2685484|Ensembl:ENSMUSG00000048534|Vega:OTTMUSG00000016704 +270156 AU019823 MGI:MGI:2143205|Ensembl:ENSMUSG00000059820|Vega:OTTMUSG00000033528 +270160 Rab39 MGI:MGI:2442855|Ensembl:ENSMUSG00000055069|Vega:OTTMUSG00000030703 +270162 Elmod1 MGI:MGI:3583900|Ensembl:ENSMUSG00000041986|Vega:OTTMUSG00000063197 +270163 Myo9a MGI:MGI:107735|Ensembl:ENSMUSG00000039585|Vega:OTTMUSG00000034123 +270166 Clpx MGI:MGI:1346017|Ensembl:ENSMUSG00000015357|Vega:OTTMUSG00000031828 +270185 BC043934 MGI:MGI:2679715 +270190 Ephb1 MGI:MGI:1096337|Ensembl:ENSMUSG00000032537|Vega:OTTMUSG00000021086 +270192 Rab6b MGI:MGI:107283|Ensembl:ENSMUSG00000032549|Vega:OTTMUSG00000048481 +270198 Pfkfb4 MGI:MGI:2687284|Ensembl:ENSMUSG00000025648|Vega:OTTMUSG00000027454 +270201 Klhl18 MGI:MGI:2143315|Ensembl:ENSMUSG00000054792|Vega:OTTMUSG00000023208 +270210 Zfp651 MGI:MGI:2670992|Ensembl:ENSMUSG00000013419|Vega:OTTMUSG00000062664 +270234 Rpl23a-ps7 MGI:MGI:3645824 +270328 Gsdmc3 MGI:MGI:3580656|Ensembl:ENSMUSG00000055827|Vega:OTTMUSG00000045283 +270499 Gm5058 MGI:MGI:3647682 +270533 LOC270533 - +270599 Gm648 MGI:MGI:2685494|Ensembl:ENSMUSG00000064016|Vega:OTTMUSG00000017581 +270624 Spin4 MGI:MGI:2444925|Ensembl:ENSMUSG00000071722|Vega:OTTMUSG00000018028 +270627 Taf1 MGI:MGI:1336878|Ensembl:ENSMUSG00000031314|Vega:OTTMUSG00000018200 +270665 Gm5060 MGI:MGI:3646911 +270669 Mbtps2 MGI:MGI:2444506|Ensembl:ENSMUSG00000046873|Vega:OTTMUSG00000019403 +270672 Map3k15 MGI:MGI:2448588|Ensembl:ENSMUSG00000031303|Vega:OTTMUSG00000019447 +270685 Mthfd1l MGI:MGI:1924836|Ensembl:ENSMUSG00000040675|Vega:OTTMUSG00000029856 +270711 Fam26d MGI:MGI:2685489|Ensembl:ENSMUSG00000039508 +270757 Bpifc MGI:MGI:3026884|Ensembl:ENSMUSG00000050108|Vega:OTTMUSG00000021304 +270802 BC048403 MGI:MGI:2670984|Ensembl:ENSMUSG00000053684|Vega:OTTMUSG00000027722 +270893 Tmem132e MGI:MGI:2685490|Ensembl:ENSMUSG00000020701|Vega:OTTMUSG00000000911 +270906 Prr11 MGI:MGI:2444496|Ensembl:ENSMUSG00000020493|Vega:OTTMUSG00000001219 +271005 Klhdc1 MGI:MGI:2672853|Ensembl:ENSMUSG00000051890|Vega:OTTMUSG00000023769 +271022 Gm10264 MGI:MGI:3646909 +271036 Catsperb MGI:MGI:2443988|Ensembl:ENSMUSG00000047014 +271047 Serpina3b MGI:MGI:2182835|Ensembl:ENSMUSG00000066364|Vega:OTTMUSG00000027589 +271127 Adamts16 MGI:MGI:2429637|Ensembl:ENSMUSG00000049538|Vega:OTTMUSG00000020970 +271144 Ankdd1b MGI:MGI:2444730|Ensembl:ENSMUSG00000047117|Vega:OTTMUSG00000042851 +271171 Tpi-rs9 MGI:MGI:98807 +271209 Rp1l1 MGI:MGI:2384303|Ensembl:ENSMUSG00000046049 +271221 Rubcnl MGI:MGI:2685590|Ensembl:ENSMUSG00000034959 +271278 BC024139 MGI:MGI:2442591|Ensembl:ENSMUSG00000044361|Vega:OTTMUSG00000033645 +271300 Cyp2d41-ps MGI:MGI:3645691 +271305 Phf21b MGI:MGI:2443812|Ensembl:ENSMUSG00000016624|Vega:OTTMUSG00000034906 +271374 Gm5063 MGI:MGI:3648069 +271375 Cd200r2 MGI:MGI:3042847|Ensembl:ENSMUSG00000090176|Vega:OTTMUSG00000014974 +271377 Zbtb11 MGI:MGI:2443876|Ensembl:ENSMUSG00000022601|Vega:OTTMUSG00000044524 +271424 Ip6k3 MGI:MGI:3045325|Ensembl:ENSMUSG00000024210|Vega:OTTMUSG00000028132 +271457 Rab5a MGI:MGI:105926|Ensembl:ENSMUSG00000017831 +271505 Gm5064 MGI:MGI:3649060 +271508 4933408B17Rik MGI:MGI:3045347|Ensembl:ENSMUSG00000049357|Vega:OTTMUSG00000034147 +271521 Gm1859 MGI:MGI:3037717 +271564 Vps13a MGI:MGI:2444304|Ensembl:ENSMUSG00000046230 +271639 Adcy10 MGI:MGI:2660854|Ensembl:ENSMUSG00000026567|Vega:OTTMUSG00000021452 +271697 Cdk15 MGI:MGI:3583944|Ensembl:ENSMUSG00000026023|Vega:OTTMUSG00000029822 +271711 Tmem169 MGI:MGI:2442781|Ensembl:ENSMUSG00000026188|Vega:OTTMUSG00000026656 +271786 Galnt13 MGI:MGI:2139447|Ensembl:ENSMUSG00000060988|Vega:OTTMUSG00000015443 +271788 Gm13531 MGI:MGI:3651643 +271813 Agbl2 MGI:MGI:2443254|Ensembl:ENSMUSG00000040812|Vega:OTTMUSG00000014285 +271842 Rpusd2 MGI:MGI:1918066|Ensembl:ENSMUSG00000027324|Vega:OTTMUSG00000015765 +271844 Pla2g4f MGI:MGI:2685493|Ensembl:ENSMUSG00000046971|Vega:OTTMUSG00000015278 +271849 Shc4 MGI:MGI:2655364|Ensembl:ENSMUSG00000035109|Vega:OTTMUSG00000015349 +271887 Rbbp8nl MGI:MGI:3606212|Ensembl:ENSMUSG00000038980|Vega:OTTMUSG00000016298 +271944 C2cd4d MGI:MGI:2685505|Ensembl:ENSMUSG00000091648|Vega:OTTMUSG00000052038 +271970 Arsj MGI:MGI:2443513|Ensembl:ENSMUSG00000046561|Vega:OTTMUSG00000035307 +271981 Tbck MGI:MGI:2445052|Ensembl:ENSMUSG00000028030|Vega:OTTMUSG00000055158 +272009 Srsf12 MGI:MGI:2661424|Ensembl:ENSMUSG00000054679|Vega:OTTMUSG00000004917 +272027 Tstd2 MGI:MGI:3039624|Ensembl:ENSMUSG00000035495|Vega:OTTMUSG00000006832 +272031 Plppr1 MGI:MGI:2445015|Ensembl:ENSMUSG00000063446|Vega:OTTMUSG00000006909 +272158 Poln MGI:MGI:2675617|Ensembl:ENSMUSG00000045102|Vega:OTTMUSG00000055712 +272322 Arntl2 MGI:MGI:2684845|Ensembl:ENSMUSG00000040187|Vega:OTTMUSG00000023496 +272347 Zfp398 MGI:MGI:1917856|Ensembl:ENSMUSG00000062519|Vega:OTTMUSG00000022842 +272350 Gm5065 MGI:MGI:3643170|Ensembl:ENSMUSG00000048398|Vega:OTTMUSG00000037749 +272359 Irf2bp1 MGI:MGI:2442159|Ensembl:ENSMUSG00000044030|Vega:OTTMUSG00000058461 +272381 Lrrc4b MGI:MGI:3027390|Ensembl:ENSMUSG00000047085|Vega:OTTMUSG00000027279 +272382 Spib MGI:MGI:892986|Ensembl:ENSMUSG00000008193|Vega:OTTMUSG00000058333 +272396 Tarsl2 MGI:MGI:2444486|Ensembl:ENSMUSG00000030515|Vega:OTTMUSG00000024932 +272411 B3gnt6 MGI:MGI:3039603|Ensembl:ENSMUSG00000074004|Vega:OTTMUSG00000058765 +272428 Acsm5 MGI:MGI:2444086|Ensembl:ENSMUSG00000030972|Vega:OTTMUSG00000059117 +272465 Tmem255b MGI:MGI:2685533|Ensembl:ENSMUSG00000038457|Vega:OTTMUSG00000060910 +272538 Tango6 MGI:MGI:2142786|Ensembl:ENSMUSG00000041949|Vega:OTTMUSG00000061949 +272551 Gins2 MGI:MGI:1921019|Ensembl:ENSMUSG00000031821|Vega:OTTMUSG00000031584 +272589 Tbcel MGI:MGI:1925543|Ensembl:ENSMUSG00000037287|Vega:OTTMUSG00000033562 +272633 Gm5066 MGI:MGI:3645897 +272636 Esyt3 MGI:MGI:1098699|Ensembl:ENSMUSG00000037681|Vega:OTTMUSG00000048235 +272643 Prss43 MGI:MGI:2684822|Ensembl:ENSMUSG00000058398|Vega:OTTMUSG00000052496 +272667 Smok4a MGI:MGI:3036233|Ensembl:ENSMUSG00000079711 +272714 Gm5067 MGI:MGI:3644982 +272790 Magee2 MGI:MGI:2148316|Ensembl:ENSMUSG00000031224|Vega:OTTMUSG00000018100 +276712 293M16.R MGI:MGI:2388984 +276713 333P17.R MGI:MGI:2388985 +276714 389D19.R MGI:MGI:2388987 +276715 469O12.R MGI:MGI:2388991 +276742 Taar7e MGI:MGI:3527445|Ensembl:ENSMUSG00000100689|Vega:OTTMUSG00000019221 +276770 Eif5a MGI:MGI:106248|Ensembl:ENSMUSG00000078812|Vega:OTTMUSG00000006023 +276809 Gm11624 MGI:MGI:3649733 +276829 Smtnl2 MGI:MGI:2442764|Ensembl:ENSMUSG00000045667|Vega:OTTMUSG00000006108 +276846 Pigs MGI:MGI:2687325|Ensembl:ENSMUSG00000041958|Vega:OTTMUSG00000000097 +276852 D11Wsu47e MGI:MGI:106356|Ensembl:ENSMUSG00000041623|Vega:OTTMUSG00000003401 +276865 Olfr1371 MGI:MGI:3031205|Ensembl:ENSMUSG00000060170|Vega:OTTMUSG00000005621 +276891 Timd4 MGI:MGI:2445125|Ensembl:ENSMUSG00000055546|Vega:OTTMUSG00000005508 +276905 Armc7 MGI:MGI:2679719|Ensembl:ENSMUSG00000057219|Vega:OTTMUSG00000003446 +276919 Gemin4 MGI:MGI:2449313|Ensembl:ENSMUSG00000049396|Vega:OTTMUSG00000006230 +276920 Ccdc42 MGI:MGI:3045254|Ensembl:ENSMUSG00000045915|Vega:OTTMUSG00000005948 +276941 Gm12129 MGI:MGI:3651508 +276950 Slfn8 MGI:MGI:2672859|Ensembl:ENSMUSG00000035208|Vega:OTTMUSG00000000922 +276952 Rasl10b MGI:MGI:2685575|Ensembl:ENSMUSG00000020684|Vega:OTTMUSG00000000933 +277010 Marveld1 MGI:MGI:2147570|Ensembl:ENSMUSG00000044345|Vega:OTTMUSG00000036866 +277089 S100a11-ps MGI:MGI:3645720 +277146 Trav6d-4 MGI:MGI:2685547|IMGT/GENE-DB:TRAV6D-4 +277154 Nynrin MGI:MGI:2652872|Ensembl:ENSMUSG00000075592 +277203 Tm4sf19 MGI:MGI:3645933|Ensembl:ENSMUSG00000079625|Vega:OTTMUSG00000050040 +277225 Ldha-ps3 MGI:MGI:96762 +277250 Kdm3b MGI:MGI:1923356|Ensembl:ENSMUSG00000038773 +277328 Trpa1 MGI:MGI:3522699|Ensembl:ENSMUSG00000032769|Vega:OTTMUSG00000049207 +277333 Gm5069 MGI:MGI:3644516 +277343 Wfdc8 MGI:MGI:2685552|Ensembl:ENSMUSG00000070533|Vega:OTTMUSG00000001096 +277345 Wfdc16 MGI:MGI:2670994|Ensembl:ENSMUSG00000070530|Vega:OTTMUSG00000016287 +277353 Tcfl5 MGI:MGI:2672878|Ensembl:ENSMUSG00000038932|Vega:OTTMUSG00000016345 +277360 Prex1 MGI:MGI:3040696|Ensembl:ENSMUSG00000039621|Vega:OTTMUSG00000001160 +277396 Klhl23 MGI:MGI:2683536|Ensembl:ENSMUSG00000042155|Vega:OTTMUSG00000013033 +277414 Trp53i11 MGI:MGI:2670995|Ensembl:ENSMUSG00000068735|Vega:OTTMUSG00000014529 +277432 Vstm2l MGI:MGI:2685537|Ensembl:ENSMUSG00000037843|Vega:OTTMUSG00000015887 +277463 Gpr107 MGI:MGI:2139054|Ensembl:ENSMUSG00000000194|Vega:OTTMUSG00000011925 +277468 Slc39a12 MGI:MGI:2139274|Ensembl:ENSMUSG00000036949|Vega:OTTMUSG00000011408 +277496 Lkaaear1 MGI:MGI:2685538|Ensembl:ENSMUSG00000045794|Vega:OTTMUSG00000016813 +277562 Olfr1286 MGI:MGI:3031120|Ensembl:ENSMUSG00000096703|Vega:OTTMUSG00000015068 +277589 Gm5070 MGI:MGI:3643219 +277666 Gm13078 MGI:MGI:3650231|Ensembl:ENSMUSG00000046435|Vega:OTTMUSG00000010322 +277667 Gm13089 MGI:MGI:3649972|Ensembl:ENSMUSG00000070617|Vega:OTTMUSG00000010333 +277668 Gm13088 MGI:MGI:3649971|Ensembl:ENSMUSG00000078513|Vega:OTTMUSG00000010332 +277692 Rps19-ps3 MGI:MGI:3701125|Ensembl:ENSMUSG00000080059 +277707 Ccdc50-ps MGI:MGI:3651098 +277743 Fam131c MGI:MGI:2685539|Ensembl:ENSMUSG00000006218|Vega:OTTMUSG00000010294 +277744 Gm694 MGI:MGI:2685540|Ensembl:ENSMUSG00000070637|Vega:OTTMUSG00000010293 +277753 Cyp4a12a MGI:MGI:88612|Ensembl:ENSMUSG00000066071|Vega:OTTMUSG00000008615 +277771 Gm12378 MGI:MGI:3651610 +277773 Fam205c MGI:MGI:2679716|Ensembl:ENSMUSG00000050141|Vega:OTTMUSG00000006597 +277854 Depdc5 MGI:MGI:2141101|Ensembl:ENSMUSG00000037426|Vega:OTTMUSG00000028553 +277898 Slc15a5 MGI:MGI:3607714|Ensembl:ENSMUSG00000044378|Vega:OTTMUSG00000022836 +277899 Gm725 MGI:MGI:2685571 +277935 Olfr519 MGI:MGI:3030353|Ensembl:ENSMUSG00000066239|Vega:OTTMUSG00000055595 +277939 C2cd3 MGI:MGI:2142166|Ensembl:ENSMUSG00000047248|Vega:OTTMUSG00000031837 +277973 Slc9a5 MGI:MGI:2685542|Ensembl:ENSMUSG00000014786|Vega:OTTMUSG00000062046 +277978 Exoc3l MGI:MGI:3041195|Ensembl:ENSMUSG00000043251|Vega:OTTMUSG00000062042 +278087 Gm5071 MGI:MGI:3645128 +278097 Armcx6 MGI:MGI:2147993|Ensembl:ENSMUSG00000050394|Vega:OTTMUSG00000019457 +278167 Gm5072 MGI:MGI:3643982|Ensembl:ENSMUSG00000094861|Vega:OTTMUSG00000017989 +278174 Ssxb3 MGI:MGI:2446772|Ensembl:ENSMUSG00000079701|Vega:OTTMUSG00000016720 +278180 Vsig4 MGI:MGI:2679720|Ensembl:ENSMUSG00000044206|Vega:OTTMUSG00000018498 +278181 Gm5073 MGI:MGI:3643718 +278203 Spaca5 MGI:MGI:2685564|Ensembl:ENSMUSG00000037167|Vega:OTTMUSG00000017204 +278240 Spin2c MGI:MGI:3605548|Ensembl:ENSMUSG00000046550|Vega:OTTMUSG00000019374 +278255 Tex13c3 MGI:MGI:3037654|Ensembl:ENSMUSG00000068149|Vega:OTTMUSG00000017026 +278279 Tmtc2 MGI:MGI:1914057|Ensembl:ENSMUSG00000036019|Vega:OTTMUSG00000025048 +278304 Zfp385c MGI:MGI:3608347|Ensembl:ENSMUSG00000014198|Vega:OTTMUSG00000002026 +278507 Wfikkn2 MGI:MGI:2669209|Ensembl:ENSMUSG00000044177|Vega:OTTMUSG00000001708 +278672 Duxbl1 MGI:MGI:1916048|Ensembl:ENSMUSG00000048502|Vega:OTTMUSG00000037595 +278676 AY358078 MGI:MGI:2682312|Ensembl:ENSMUSG00000050961|Vega:OTTMUSG00000036427 +278679 Apol7b MGI:MGI:3583950|Ensembl:ENSMUSG00000068252|Vega:OTTMUSG00000028102 +278725 E130310I04Rik MGI:MGI:3046461 +278795 Lrrc10b MGI:MGI:2685551|Ensembl:ENSMUSG00000090291 +279028 Adamts13 MGI:MGI:2685556|Ensembl:ENSMUSG00000014852|Vega:OTTMUSG00000011842 +279029 Stkld1 MGI:MGI:2685557|Ensembl:ENSMUSG00000049897|Vega:OTTMUSG00000011848 +279056 Gm14140 MGI:MGI:3649719 +279067 Gm13777 MGI:MGI:3650376 +279185 Gm13083 MGI:MGI:3650232|Ensembl:ENSMUSG00000066688|Vega:OTTMUSG00000010327 +279499 Kctd19 MGI:MGI:3045294|Ensembl:ENSMUSG00000051648|Vega:OTTMUSG00000036565 +279561 Wnk3 MGI:MGI:2652875|Ensembl:ENSMUSG00000041245|Vega:OTTMUSG00000019169 +279572 Tlr13 MGI:MGI:3045213|Ensembl:ENSMUSG00000033777|Vega:OTTMUSG00000018275 +279610 E530001F21Rik MGI:MGI:3036288 +279618 Gm715 MGI:MGI:2685561 +279653 Pcdh19 MGI:MGI:2685563|Ensembl:ENSMUSG00000051323|Vega:OTTMUSG00000018675 +279706 Nup62cl MGI:MGI:2685565|Ensembl:ENSMUSG00000072944|Vega:OTTMUSG00000018853 +279766 Rhbdd3 MGI:MGI:2444684|Ensembl:ENSMUSG00000034175|Vega:OTTMUSG00000005080 +279872 Trav9n-1 MGI:MGI:3809200 +279882 Trav9n-4 MGI:MGI:3583949|IMGT/GENE-DB:TRAV9N-4 +280047 Gm5075 MGI:MGI:3645483 +280121 Rplp1-ps1 MGI:MGI:3646640 +280287 Kiss1 MGI:MGI:2663985|Ensembl:ENSMUSG00000102367|Vega:OTTMUSG00000044883 +280408 Rilp MGI:MGI:2144271|Ensembl:ENSMUSG00000038195|Vega:OTTMUSG00000006206 +280411 Lix1l MGI:MGI:3036267|Ensembl:ENSMUSG00000049288|Vega:OTTMUSG00000053139 +280621 Selenov MGI:MGI:3608324|Ensembl:ENSMUSG00000046750|Vega:OTTMUSG00000021137 +280635 Emilin3 MGI:MGI:2389142|Ensembl:ENSMUSG00000050700|Vega:OTTMUSG00000001050 +280645 B3gat2 MGI:MGI:2389490|Ensembl:ENSMUSG00000026156|Vega:OTTMUSG00000026519 +280662 Afm MGI:MGI:2429409|Ensembl:ENSMUSG00000029369|Vega:OTTMUSG00000033292 +280667 Adam1b MGI:MGI:2429506|Ensembl:ENSMUSG00000062438|Vega:OTTMUSG00000023476 +280668 Adam1a MGI:MGI:2429504|Ensembl:ENSMUSG00000072647|Vega:OTTMUSG00000023479 +282619 Sbsn MGI:MGI:2446326|Ensembl:ENSMUSG00000046056|Vega:OTTMUSG00000059371 +282620 D15Kus1 MGI:MGI:1928954 +282621 D15Kus2 MGI:MGI:1928955 +282622 D15Kus3 MGI:MGI:1928956 +282623 D15Kus4 MGI:MGI:1928957 +282624 D15Kus5 MGI:MGI:2429925 +282626 D15Gsk2 MGI:MGI:2429857 +282627 D15Gsk3 MGI:MGI:2429954 +282663 Serpinb1b MGI:MGI:2445361|Ensembl:ENSMUSG00000051029|Vega:OTTMUSG00000000700 +282665 Serpinb1-ps1 MGI:MGI:2445366 +286940 Flnb MGI:MGI:2446089|Ensembl:ENSMUSG00000025278|Vega:OTTMUSG00000036302 +286942 Kif19a MGI:MGI:2447024|Ensembl:ENSMUSG00000010021|Vega:OTTMUSG00000003453 +286951 Eif2c5 MGI:MGI:2446636 +286968 6530437J22Rik MGI:MGI:1925320 +317652 Klk15 MGI:MGI:2447533|Ensembl:ENSMUSG00000055193|Vega:OTTMUSG00000027231 +317653 Klk14 MGI:MGI:2447564|Ensembl:ENSMUSG00000044737|Vega:OTTMUSG00000027218 +317677 C1s2 MGI:MGI:3644269|Ensembl:ENSMUSG00000079343|Vega:OTTMUSG00000028980 +317690 Cyp1a1-ps MGI:MGI:2447801 +317717 Sec22a MGI:MGI:2447876|Ensembl:ENSMUSG00000034473|Vega:OTTMUSG00000025485 +317750 Slc24a5 MGI:MGI:2677271|Ensembl:ENSMUSG00000035183|Vega:OTTMUSG00000015345 +317755 Zar1 MGI:MGI:2180337|Ensembl:ENSMUSG00000063935|Vega:OTTMUSG00000026978 +317757 Gimap5 MGI:MGI:2442232|Ensembl:ENSMUSG00000043505|Vega:OTTMUSG00000026930 +317758 Gimap9 MGI:MGI:3511744|Ensembl:ENSMUSG00000051124|Vega:OTTMUSG00000022274 +319146 Ifnz MGI:MGI:2448469|Ensembl:ENSMUSG00000096854|Vega:OTTMUSG00000011287 +319148 Hist1h3c MGI:MGI:2448320|Ensembl:ENSMUSG00000069310|Vega:OTTMUSG00000000583 +319149 Hist1h3d MGI:MGI:2448322|Ensembl:ENSMUSG00000099583|Vega:OTTMUSG00000000561 +319150 Hist1h3b MGI:MGI:2448319|Ensembl:ENSMUSG00000069267|Vega:OTTMUSG00000000587 +319151 Hist1h3e MGI:MGI:2448326|Ensembl:ENSMUSG00000069273|Vega:OTTMUSG00000000554 +319152 Hist1h3h MGI:MGI:2448349|Ensembl:ENSMUSG00000101355|Vega:OTTMUSG00000000428 +319153 Hist1h3i MGI:MGI:2448350|Ensembl:ENSMUSG00000101972|Vega:OTTMUSG00000000433 +319154 Hist2h3b MGI:MGI:2448351|Ensembl:ENSMUSG00000074403|Vega:OTTMUSG00000042083 +319155 Hist1h4c MGI:MGI:2448421|Ensembl:ENSMUSG00000060678|Vega:OTTMUSG00000000559 +319156 Hist1h4d MGI:MGI:2448423|Ensembl:ENSMUSG00000061482|Vega:OTTMUSG00000000562 +319157 Hist1h4f MGI:MGI:2448425|Ensembl:ENSMUSG00000069274|Vega:OTTMUSG00000000573 +319158 Hist1h4i MGI:MGI:2448432|Ensembl:ENSMUSG00000060639|Vega:OTTMUSG00000000471 +319159 Hist1h4j MGI:MGI:2448436|Ensembl:ENSMUSG00000067455|Vega:OTTMUSG00000000434 +319160 Hist1h4k MGI:MGI:2448439|Ensembl:ENSMUSG00000064288|Vega:OTTMUSG00000000445 +319161 Hist1h4n MGI:MGI:4843992|Ensembl:ENSMUSG00000069305|Vega:OTTMUSG00000000447 +319162 Hist3h2a MGI:MGI:2448458|Ensembl:ENSMUSG00000078851|Vega:OTTMUSG00000011797 +319163 Hist1h2aa MGI:MGI:2448285|Ensembl:ENSMUSG00000060081|Vega:OTTMUSG00000000591 +319164 Hist1h2ac MGI:MGI:2448287|Ensembl:ENSMUSG00000069270|Vega:OTTMUSG00000000565 +319165 Hist1h2ad MGI:MGI:2448289|Ensembl:ENSMUSG00000071478|Vega:OTTMUSG00000000560 +319166 Hist1h2ae MGI:MGI:2448290|Ensembl:ENSMUSG00000069272|Vega:OTTMUSG00000000555 +319167 Hist1h2ag MGI:MGI:2448293|Ensembl:ENSMUSG00000069301|Vega:OTTMUSG00000000470 +319168 Hist1h2ah MGI:MGI:2448295|Ensembl:ENSMUSG00000069302|Vega:OTTMUSG00000000473 +319169 Hist1h2ak MGI:MGI:2448297|Ensembl:ENSMUSG00000063021|Vega:OTTMUSG00000000429 +319170 Hist1h2an MGI:MGI:2448300|Ensembl:ENSMUSG00000069309|Vega:OTTMUSG00000000435 +319171 Hist1h2ap MGI:MGI:3710573|Ensembl:ENSMUSG00000094777|Vega:OTTMUSG00000000448 +319172 Hist1h2ab MGI:MGI:2448306|Ensembl:ENSMUSG00000061615|Vega:OTTMUSG00000000580 +319173 Hist1h2af MGI:MGI:2448309|Ensembl:ENSMUSG00000061991|Vega:OTTMUSG00000000569 +319174 Hist1h2aj MGI:MGI:2448312 +319176 Hist2h2ac MGI:MGI:2448316|Ensembl:ENSMUSG00000068855|Vega:OTTMUSG00000021931 +319177 Hist1h2ba MGI:MGI:2448375|Ensembl:ENSMUSG00000050799|Vega:OTTMUSG00000000590 +319178 Hist1h2bb MGI:MGI:2448377|Ensembl:ENSMUSG00000075031|Vega:OTTMUSG00000000581 +319179 Hist1h2be MGI:MGI:2448380|Ensembl:ENSMUSG00000047246|Vega:OTTMUSG00000000563 +319180 Hist1h2bf MGI:MGI:2448383|Ensembl:ENSMUSG00000069268|Vega:OTTMUSG00000000558 +319181 Hist1h2bg MGI:MGI:2448386|Ensembl:ENSMUSG00000058385|Vega:OTTMUSG00000000556 +319182 Hist1h2bh MGI:MGI:2448387|Ensembl:ENSMUSG00000064168|Vega:OTTMUSG00000000571 +319183 Hist1h2bj MGI:MGI:2448388|Ensembl:ENSMUSG00000069300|Vega:OTTMUSG00000000476 +319184 Hist1h2bk MGI:MGI:2448399|Ensembl:ENSMUSG00000062727|Vega:OTTMUSG00000000475 +319185 Hist1h2bl MGI:MGI:2448403|Ensembl:ENSMUSG00000094338|Vega:OTTMUSG00000000443 +319186 Hist1h2bm MGI:MGI:2448404|Ensembl:ENSMUSG00000096807|Vega:OTTMUSG00000000432 +319187 Hist1h2bn MGI:MGI:2448407|Ensembl:ENSMUSG00000095217|Vega:OTTMUSG00000000430 +319188 Hist1h2bp MGI:MGI:2448409|Ensembl:ENSMUSG00000069308|Vega:OTTMUSG00000000436 +319189 Hist2h2bb MGI:MGI:2448413|Ensembl:ENSMUSG00000105827|Vega:OTTMUSG00000042084 +319190 Hist2h2be MGI:MGI:2448415|Ensembl:ENSMUSG00000068854|Vega:OTTMUSG00000021932 +319191 Hist1h2ai MGI:MGI:2448457|Ensembl:ENSMUSG00000071516|Vega:OTTMUSG00000000444 +319192 Hist2h2aa2 MGI:MGI:2448283|Ensembl:ENSMUSG00000063954|Vega:OTTMUSG00000042072 +319195 Rpl17 MGI:MGI:2448270|Ensembl:ENSMUSG00000062328 +319196 Ankef1 MGI:MGI:2441685|Ensembl:ENSMUSG00000074771|Vega:OTTMUSG00000015561 +319197 Gpr4 MGI:MGI:2441992|Ensembl:ENSMUSG00000044317|Vega:OTTMUSG00000058601 +319200 Gpr82 MGI:MGI:2441734|Ensembl:ENSMUSG00000047678|Vega:OTTMUSG00000016910 +319204 3632413A11Rik MGI:MGI:2441665 +319205 4732499D12Rik MGI:MGI:2441672 +319207 Pgbd1 MGI:MGI:2441675|Ensembl:ENSMUSG00000055313|Vega:OTTMUSG00000000413 +319208 4930403D09Rik MGI:MGI:2441677|Ensembl:ENSMUSG00000087122 +319210 Vmn2r-ps11 MGI:MGI:2441682|Ensembl:ENSMUSG00000097538 +319211 Nol4 MGI:MGI:2441684|Ensembl:ENSMUSG00000041923|Vega:OTTMUSG00000035216 +319213 4930579C12Rik MGI:MGI:2441687 +319215 4932413F04Rik MGI:MGI:2441690|Ensembl:ENSMUSG00000099616 +319216 4932441J04Rik MGI:MGI:2441691|Ensembl:ENSMUSG00000097216 +319217 Vmn2r7 MGI:MGI:2441693|Ensembl:ENSMUSG00000062200|Vega:OTTMUSG00000030605 +319220 5430427N15Rik MGI:MGI:2441699 +319223 5930420M18Rik MGI:MGI:2441703 +319224 6330410L21Rik MGI:MGI:2441710|Ensembl:ENSMUSG00000105960 +319226 6430500G05Rik MGI:MGI:2441715 +319229 Sctr MGI:MGI:2441720|Ensembl:ENSMUSG00000026387|Vega:OTTMUSG00000049072 +319230 6720417O19Rik MGI:MGI:2441721 +319233 8030474H12Rik MGI:MGI:2441727 +319235 9130204K15Rik MGI:MGI:2441733 +319236 Trim12c MGI:MGI:4821183|Ensembl:ENSMUSG00000057143|Vega:OTTMUSG00000019193 +319237 9330112F22Rik MGI:MGI:2441736 +319238 9330123L03Rik MGI:MGI:2441737 +319239 Npsr1 MGI:MGI:2441738|Ensembl:ENSMUSG00000043659|Vega:OTTMUSG00000024228 +319240 9330159N05Rik MGI:MGI:2441739 +319243 9430062P05Rik MGI:MGI:2441746 +319244 9430091N11Rik MGI:MGI:2441747 +319245 9430097D07Rik MGI:MGI:2441749 +319246 9530056E24Rik MGI:MGI:2441750 +319247 9530080O11Rik MGI:MGI:2441751|Ensembl:ENSMUSG00000044125 +319251 9630001P10Rik MGI:MGI:2441755|Ensembl:ENSMUSG00000097825 +319253 9630030I15Rik MGI:MGI:2441757 +319254 9630039A02Rik MGI:MGI:2441759 +319259 Bricd5 MGI:MGI:2441766|Ensembl:ENSMUSG00000045744 +319262 Fchsd1 MGI:MGI:2441771|Ensembl:ENSMUSG00000038524|Vega:OTTMUSG00000036304 +319263 Pcmtd1 MGI:MGI:2441773|Ensembl:ENSMUSG00000051285|Vega:OTTMUSG00000043373 +319264 A130006I12Rik MGI:MGI:2441774 +319266 A130010J15Rik MGI:MGI:2441776|Ensembl:ENSMUSG00000079144|Vega:OTTMUSG00000020793 +319268 A130026P03Rik MGI:MGI:2441778 +319269 A130040M12Rik MGI:MGI:2441779 +319271 A130072N09Rik MGI:MGI:2441781 +319272 A130077B15Rik MGI:MGI:2441782|Ensembl:ENSMUSG00000112095 +319276 A230038B01Rik MGI:MGI:2441786 +319277 Washc4 MGI:MGI:2441787|Ensembl:ENSMUSG00000034560 +319278 A230050P20Rik MGI:MGI:2441788|Ensembl:ENSMUSG00000038884|Vega:OTTMUSG00000042070 +319282 A330095P18Rik MGI:MGI:2441793 +319283 A430042F24Rik MGI:MGI:2441795 +319284 A430055H19Rik MGI:MGI:2441796 +319285 A430061O12Rik MGI:MGI:2441797 +319287 A430073I11Rik MGI:MGI:2441799 +319289 A430087P03Rik MGI:MGI:2441801 +319290 A430091L06Rik MGI:MGI:2441802 +319293 A530099J19Rik MGI:MGI:2441809|Vega:OTTMUSG00000033639 +319297 A630033J11Rik MGI:MGI:2441815 +319299 A630075K04Rik MGI:MGI:2441819 +319302 A730043B01Rik MGI:MGI:2441822 +319303 A730052K04Rik MGI:MGI:2441824 +319304 A730081D07Rik MGI:MGI:2441825 +319305 A730087J23Rik MGI:MGI:2441826 +319306 A730099G02Rik MGI:MGI:2441828 +319308 A830012C17Rik MGI:MGI:2441830 +319311 A830037D11Rik MGI:MGI:2441833 +319313 A830092I05Rik MGI:MGI:2441836 +319314 A930001C03Rik MGI:MGI:2441838|Ensembl:ENSMUSG00000087132 +319317 Snhg11 MGI:MGI:2441845|Ensembl:ENSMUSG00000044349|Vega:OTTMUSG00000015934 +319319 B230214O09Rik MGI:MGI:2441851 +319320 B230219N05Rik MGI:MGI:2441852 +319321 B230220N19Rik MGI:MGI:2441853 +319322 Sf3b2 MGI:MGI:2441856|Ensembl:ENSMUSG00000024853 +319323 B430119L08Rik MGI:MGI:2441857 +319327 B930032C10Rik MGI:MGI:2441865 +319330 B930063I24Rik MGI:MGI:2441868 +319331 B930086H10Rik MGI:MGI:2441870 +319333 C030012N03Rik MGI:MGI:2441874 +319334 C030017G13Rik MGI:MGI:2441875 +319336 C130036L24Rik MGI:MGI:2441877|Ensembl:ENSMUSG00000073627 +319339 C130063H03Rik MGI:MGI:2441882 +319341 C230007H23Rik MGI:MGI:2441891 +319342 C230034O21Rik MGI:MGI:2441892 +319343 C230047L17Rik MGI:MGI:2441893 +319344 C230053D17Rik MGI:MGI:2441895 +319346 C230069I12Rik MGI:MGI:2441898 +319347 C230094B09Rik MGI:MGI:2441900 +319351 C530025M11Rik MGI:MGI:2441907 +319352 Pianp MGI:MGI:2441908|Ensembl:ENSMUSG00000030329|Vega:OTTMUSG00000029032 +319354 C530034L13Rik MGI:MGI:2441911 +319355 C530036F05Rik MGI:MGI:2441912 +319356 C530040J15Rik MGI:MGI:2441913 +319357 C530043A13Rik MGI:MGI:2441914 +319358 C530047H08Rik MGI:MGI:2441915 +319362 C730034F03Rik MGI:MGI:2441921 +319366 C920008N22Rik MGI:MGI:2441926 +319367 Ict1os MGI:MGI:2441927 +319370 Ubald2 MGI:MGI:1914635|Ensembl:ENSMUSG00000050628|Vega:OTTMUSG00000003905 +319371 D030028A08Rik MGI:MGI:2441931|Ensembl:ENSMUSG00000078700 +319377 D130012P04Rik MGI:MGI:2441939 +319385 D130061D10Rik MGI:MGI:2441948 +319386 D130062J10Rik MGI:MGI:2441949 +319387 Adgrl3 MGI:MGI:2441950|Ensembl:ENSMUSG00000037605|Vega:OTTMUSG00000029552 +319388 Irx3os MGI:MGI:2441953 +319391 D230014I24Rik MGI:MGI:2441956 +319394 D230019A03Rik MGI:MGI:2441962 +319396 D230044P21Rik MGI:MGI:2441964 +319397 D330004O07Rik MGI:MGI:2441966 +319398 D330005C11Rik MGI:MGI:2441967 +319403 D430001F17Rik MGI:MGI:2441973 +319404 D430032J08Rik MGI:MGI:2441976 +319405 D430036J16Rik MGI:MGI:2441977|Ensembl:ENSMUSG00000097466 +319406 D630004L18Rik MGI:MGI:2441979 +319407 D630033L23Rik MGI:MGI:2441983 +319412 D830013H23Rik MGI:MGI:2441990 +319413 D830016O14Rik MGI:MGI:2441993 +319415 Hs3st5 MGI:MGI:2441996|Ensembl:ENSMUSG00000044499|Vega:OTTMUSG00000036580 +319416 D930006K15Rik MGI:MGI:2441997 +319417 D930007M16Rik MGI:MGI:2441998 +319422 D930030K17Rik MGI:MGI:2442004 +319423 D930031A20Rik MGI:MGI:2442005 +319424 E030004H24Rik MGI:MGI:2442006 +319430 C5ar2 MGI:MGI:2442013|Ensembl:ENSMUSG00000074361|Vega:OTTMUSG00000060708 +319431 E030032P16Rik MGI:MGI:2442014 +319432 E030036C24Rik MGI:MGI:2442015 +319433 Serpine3 MGI:MGI:2442020|Ensembl:ENSMUSG00000091155 +319435 E230023K05Rik MGI:MGI:2442024 +319438 E330019L11Rik MGI:MGI:2442029 +319440 E430002N23Rik MGI:MGI:2442036 +319445 F630036E10Rik MGI:MGI:2442041 +319446 Dpep2 MGI:MGI:2442042|Ensembl:ENSMUSG00000053687|Vega:OTTMUSG00000031193 +319448 Fndc3a MGI:MGI:1196463|Ensembl:ENSMUSG00000033487|Vega:OTTMUSG00000034682 +319449 F830002E08Rik MGI:MGI:2442047 +319450 F830010H11Rik MGI:MGI:2442048 +319454 Rptoros MGI:MGI:2442055|Ensembl:ENSMUSG00000085081 +319455 Pld5 MGI:MGI:2442056|Ensembl:ENSMUSG00000055214|Vega:OTTMUSG00000024158 +319457 C130045F17Rik MGI:MGI:2442061 +319460 A130094D17Rik MGI:MGI:2442065 +319461 D230040N21Rik MGI:MGI:2442070 +319463 C230057M02Rik MGI:MGI:2442079 +319465 C030026K05Rik MGI:MGI:2442083 +319466 9330199G10Rik MGI:MGI:2442084|Ensembl:ENSMUSG00000114189 +319467 A930002C04Rik MGI:MGI:2442085 +319468 Ppm1h MGI:MGI:2442087|Ensembl:ENSMUSG00000034613|Vega:OTTMUSG00000032921 +319469 A230056J06Rik MGI:MGI:2442089|Ensembl:ENSMUSG00000021557 +319470 C530025M09Rik MGI:MGI:2442090 +319472 9330158H04Rik MGI:MGI:2442094|Ensembl:ENSMUSG00000073154 +319475 Zfp672 MGI:MGI:2442105|Ensembl:ENSMUSG00000049755|Vega:OTTMUSG00000005729 +319476 Lrtm1 MGI:MGI:2442106|Ensembl:ENSMUSG00000045776 +319477 6030419C18Rik MGI:MGI:2442108|Ensembl:ENSMUSG00000066607|Vega:OTTMUSG00000063282 +319478 Cxxc4 MGI:MGI:2442112|Ensembl:ENSMUSG00000044365|Vega:OTTMUSG00000042554 +319480 Itga11 MGI:MGI:2442114|Ensembl:ENSMUSG00000032243|Vega:OTTMUSG00000026249 +319481 Wdr59 MGI:MGI:2442115|Ensembl:ENSMUSG00000031959|Vega:OTTMUSG00000061792 +319482 9530053A07Rik MGI:MGI:2442118|Ensembl:ENSMUSG00000078776|Vega:OTTMUSG00000032919 +319483 D230021J17Rik MGI:MGI:2442122 +319485 D930043O14Rik MGI:MGI:2442124 +319486 A430057M04Rik MGI:MGI:2442125|Ensembl:ENSMUSG00000090564 +319487 A230028O05Rik MGI:MGI:2442126|Ensembl:ENSMUSG00000096960 +319488 A230108f24rik - +319493 A430078G23Rik MGI:MGI:2442135|Ensembl:ENSMUSG00000074497|Vega:OTTMUSG00000059162 +319495 A530060M17Rik MGI:MGI:2442137 +319496 6030432P03Rik MGI:MGI:2442138 +319497 E230020A03Rik MGI:MGI:2442139 +319499 B230208B08Rik MGI:MGI:2442149 +319500 9330168O09Rik MGI:MGI:2442150 +319503 9930038B18Rik MGI:MGI:2442156|Ensembl:ENSMUSG00000042976 +319504 Nrcam MGI:MGI:104750|Ensembl:ENSMUSG00000020598 +319506 7530428D23Rik MGI:MGI:2442162 +319508 Syt15 MGI:MGI:2442166|Ensembl:ENSMUSG00000041479|Vega:OTTMUSG00000027930 +319510 D830013E24Rik MGI:MGI:2442169 +319511 A730077B16Rik MGI:MGI:2442170 +319513 Pced1a MGI:MGI:2442177|Ensembl:ENSMUSG00000037773|Vega:OTTMUSG00000015530 +319515 A030011A13Rik MGI:MGI:2442180 +319518 Pdpr MGI:MGI:2442188|Ensembl:ENSMUSG00000033624|Vega:OTTMUSG00000031622 +319519 A430062P19Rik MGI:MGI:2442189 +319520 Dusp4 MGI:MGI:2442191|Ensembl:ENSMUSG00000031530|Vega:OTTMUSG00000016984 +319521 A730056I06Rik MGI:MGI:2442193 +319522 D930046H04Rik MGI:MGI:2442194 +319523 E330021A06Rik MGI:MGI:2442195 +319525 D330013E07Rik MGI:MGI:2442198 +319527 B230325K18Rik MGI:MGI:2442200 +319530 Zfp750 MGI:MGI:2442210|Ensembl:ENSMUSG00000039238|Vega:OTTMUSG00000004675 +319533 8030451O07Rik MGI:MGI:2442215 +319535 Zfp182 MGI:MGI:2442220|Ensembl:ENSMUSG00000054737|Vega:OTTMUSG00000017196 +319537 B230334C09Rik MGI:MGI:2442224 +319539 C130031E09Rik MGI:MGI:2442227 +319543 A730059M13Rik MGI:MGI:2442234 +319545 D430020J02Rik MGI:MGI:2442237|Ensembl:ENSMUSG00000112980 +319551 6330420H09Rik MGI:MGI:2442260|Ensembl:ENSMUSG00000109898 +319552 Spx MGI:MGI:2442262|Ensembl:ENSMUSG00000071112|Vega:OTTMUSG00000021179 +319553 A330058E17Rik MGI:MGI:2442263 +319554 Idi1 MGI:MGI:2442264|Ensembl:ENSMUSG00000058258|Vega:OTTMUSG00000040098 +319555 Nwd1 MGI:MGI:2442268|Ensembl:ENSMUSG00000048148|Vega:OTTMUSG00000034303 +319556 A330041J22Rik MGI:MGI:2442269|Ensembl:ENSMUSG00000087466 +319560 9630002D21Rik MGI:MGI:2442274 +319561 A430088I17Rik MGI:MGI:2442278 +319562 9630028B13Rik MGI:MGI:2442281|Ensembl:ENSMUSG00000051295 +319563 D130052P04Rik MGI:MGI:2442282 +319564 C230012O17Rik MGI:MGI:2442283 +319565 Syne2 MGI:MGI:2449316|Ensembl:ENSMUSG00000063450|Vega:OTTMUSG00000033019 +319566 D030034A15Rik MGI:MGI:2442288 +319569 8030445P17Rik MGI:MGI:2442299 +319571 B230219N15Rik MGI:MGI:2442302 +319572 C730027H18Rik MGI:MGI:2442303|Ensembl:ENSMUSG00000112366 +319574 Gm20735 MGI:MGI:5434091|Ensembl:ENSMUSG00000110656 +319579 Defb20 MGI:MGI:2442320|Ensembl:ENSMUSG00000049560|Vega:OTTMUSG00000015835 +319580 9630055L06Rik MGI:MGI:2442323 +319581 Xkr5 MGI:MGI:2442327|Ensembl:ENSMUSG00000039814|Vega:OTTMUSG00000020767 +319582 6430573F11Rik MGI:MGI:2442328|Ensembl:ENSMUSG00000039620|Vega:OTTMUSG00000027150 +319583 Lig4 MGI:MGI:1335098|Ensembl:ENSMUSG00000049717|Vega:OTTMUSG00000059042 +319586 Celf5 MGI:MGI:2442333|Ensembl:ENSMUSG00000034818|Vega:OTTMUSG00000030422 +319587 4930539J05Rik MGI:MGI:1922477|Ensembl:ENSMUSG00000097032 +319588 9630002A11Rik MGI:MGI:2442336 +319589 9930031P18Rik MGI:MGI:2442337 +319591 D930036K23Rik MGI:MGI:2442341 +319592 D030020J04Rik MGI:MGI:2442343 +319594 Hif1an MGI:MGI:2442345|Ensembl:ENSMUSG00000036450|Vega:OTTMUSG00000028377 +319595 D130060J10Rik MGI:MGI:2442346 +319596 D830032E09Rik MGI:MGI:2442347|Ensembl:ENSMUSG00000100457 +319601 Zfp653 MGI:MGI:2442362|Ensembl:ENSMUSG00000038895|Vega:OTTMUSG00000062329 +319603 A730009E18Rik MGI:MGI:2442371 +319604 Fam168a MGI:MGI:2442372|Ensembl:ENSMUSG00000029461|Vega:OTTMUSG00000059340 +319607 A230060L02Rik MGI:MGI:2442378 +319608 E130014H10Rik MGI:MGI:2442379 +319609 9330132A10Rik MGI:MGI:2442380 +319610 9530083O12Rik MGI:MGI:2442381 +319613 Sybu MGI:MGI:2442392|Ensembl:ENSMUSG00000022340 +319614 D830015G05Rik MGI:MGI:2442393 +319615 Zfp944 MGI:MGI:2442394|Ensembl:ENSMUSG00000033972 +319616 5930412G12Rik MGI:MGI:2442398|Ensembl:ENSMUSG00000072591 +319618 Dcp1b MGI:MGI:2442404|Ensembl:ENSMUSG00000041477|Vega:OTTMUSG00000024699 +319620 C130045I22Rik MGI:MGI:2442412 +319622 Itpripl2 MGI:MGI:2442416|Ensembl:ENSMUSG00000095115|Vega:OTTMUSG00000058994 +319625 Galm MGI:MGI:2442420|Ensembl:ENSMUSG00000035473|Vega:OTTMUSG00000031366 +319626 9530059O14Rik MGI:MGI:2442421|Ensembl:ENSMUSG00000097736 +319627 A630035D09Rik MGI:MGI:2442423 +319630 A130014H13Rik MGI:MGI:2442428 +319634 Efcab5 MGI:MGI:2442440|Ensembl:ENSMUSG00000050944|Vega:OTTMUSG00000006247 +319635 A930004J17Rik MGI:MGI:2442442 +319636 Fsd1l MGI:MGI:2442443|Ensembl:ENSMUSG00000054752|Vega:OTTMUSG00000007006 +319637 A430072C10Rik MGI:MGI:2442445 +319638 Nt5dc1 MGI:MGI:2442446|Ensembl:ENSMUSG00000039480|Vega:OTTMUSG00000023255 +319642 Rab9b MGI:MGI:2442454|Ensembl:ENSMUSG00000043463|Vega:OTTMUSG00000018802 +319646 D630013N20Rik MGI:MGI:2442462|Ensembl:ENSMUSG00000037747 +319648 4732468M13Rik MGI:MGI:2442475 +319650 A430108G06Rik MGI:MGI:2442478|Ensembl:ENSMUSG00000086851 +319651 Usp37 MGI:MGI:2442483|Ensembl:ENSMUSG00000033364|Vega:OTTMUSG00000047946 +319653 Slc25a40 MGI:MGI:2442486|Ensembl:ENSMUSG00000054099|Vega:OTTMUSG00000054323 +319654 6430537I21Rik MGI:MGI:2442487 +319655 Podxl2 MGI:MGI:2442488|Ensembl:ENSMUSG00000033152|Vega:OTTMUSG00000024320 +319657 A630049H14Rik MGI:MGI:2442490 +319659 A730091E23Rik MGI:MGI:2442493 +319660 Agmo MGI:MGI:2442495|Ensembl:ENSMUSG00000050103|Vega:OTTMUSG00000034912 +319664 E230012J19Rik MGI:MGI:2442500 +319665 A430010J10Rik MGI:MGI:2442501 +319667 B930094L07Rik MGI:MGI:2442503 +319670 Eml5 MGI:MGI:2442513|Ensembl:ENSMUSG00000051166 +319672 B130021K23Rik MGI:MGI:2442518 +319673 9330159M07Rik MGI:MGI:2442519|Ensembl:ENSMUSG00000097177 +319674 C130062D02Rik MGI:MGI:2442520 +319675 Cep295 MGI:MGI:2442521|Ensembl:ENSMUSG00000046111|Vega:OTTMUSG00000034159 +319678 D430040D24Rik MGI:MGI:2442526 +319682 D830026I12Rik MGI:MGI:2442531|Ensembl:ENSMUSG00000085171 +319683 E230008J23Rik MGI:MGI:2442532 +319684 5031425F14Rik MGI:MGI:2442533 +319685 4732496C06Rik MGI:MGI:2442534 +319688 5930422O12Rik MGI:MGI:2442538 +319689 Gm17739 MGI:MGI:5009815 +319691 D430022A14Rik MGI:MGI:2442542 +319693 9130221J17Rik MGI:MGI:2442548 +319695 Ankar MGI:MGI:2442559|Ensembl:ENSMUSG00000039342|Vega:OTTMUSG00000061672 +319697 E430016L07Rik MGI:MGI:2442561 +319699 9530051E23Rik MGI:MGI:2442565 +319700 D030074P21Rik MGI:MGI:2442568 +319701 Fbxo48 MGI:MGI:2442569|Ensembl:ENSMUSG00000044966|Vega:OTTMUSG00000005188 +319702 A830011K09Rik MGI:MGI:2442570|Ensembl:ENSMUSG00000089957 +319704 E030002G19Rik MGI:MGI:2442573 +319707 C430002N11Rik MGI:MGI:2442576|Ensembl:ENSMUSG00000101581 +319710 Frmd6 MGI:MGI:2442579|Ensembl:ENSMUSG00000048285 +319711 E230029C05Rik MGI:MGI:2442580|Ensembl:ENSMUSG00000097585 +319713 Ablim3 MGI:MGI:2442582|Ensembl:ENSMUSG00000032735 +319715 A130004G11Rik MGI:MGI:2442589 +319719 Simc1 MGI:MGI:2442599|Ensembl:ENSMUSG00000043183|Vega:OTTMUSG00000027703 +319720 9630028I04Rik MGI:MGI:2442601 +319722 E330033B04Rik MGI:MGI:2442603 +319723 9430053O09Rik MGI:MGI:2442604 +319724 B230327D02Rik MGI:MGI:2442606 +319725 A130096G17Rik MGI:MGI:2442607 +319727 A330035P11Rik MGI:MGI:2442610 +319728 E030042N06Rik MGI:MGI:2442611 +319732 D230050J18Rik MGI:MGI:2442623 +319733 A530045O15Rik MGI:MGI:2442624 +319734 Cacna2d4 MGI:MGI:2442632|Ensembl:ENSMUSG00000041460|Vega:OTTMUSG00000049377 +319735 A430036H03Rik MGI:MGI:2442639 +319737 D130051D11Rik MGI:MGI:2442642 +319739 B230303O12Rik MGI:MGI:2442644 +319740 Zfyve27 MGI:MGI:1919602|Ensembl:ENSMUSG00000018820|Vega:OTTMUSG00000035213 +319742 Mpzl3 MGI:MGI:2442647|Ensembl:ENSMUSG00000070305|Vega:OTTMUSG00000016706 +319743 9630013D21Rik MGI:MGI:2442649 +319744 E230020D15Rik MGI:MGI:2442650 +319745 D130067C23Rik MGI:MGI:2442651 +319747 C130023A14Rik MGI:MGI:2442654 +319748 Zfp865 MGI:MGI:2442656|Ensembl:ENSMUSG00000074405|Vega:OTTMUSG00000022335 +319750 A230009B12Rik MGI:MGI:2442666|Ensembl:ENSMUSG00000089633 +319752 B230209E15Rik MGI:MGI:2442668 +319754 C530005L23Rik MGI:MGI:2442670 +319755 6330566A10Rik MGI:MGI:2442672 +319756 9330118A15Rik MGI:MGI:2442673 +319757 Smo MGI:MGI:108075|Ensembl:ENSMUSG00000001761|Vega:OTTMUSG00000013446 +319758 Rfx7 MGI:MGI:2442675|Ensembl:ENSMUSG00000037674|Vega:OTTMUSG00000044716 +319760 D130020L05Rik MGI:MGI:2450270|Ensembl:ENSMUSG00000097121 +319764 A730046J19Rik MGI:MGI:2442684|Ensembl:ENSMUSG00000085139|Vega:OTTMUSG00000018859 +319765 Igf2bp2 MGI:MGI:1890358|Ensembl:ENSMUSG00000033581|Vega:OTTMUSG00000025859 +319766 5330409N07Rik MGI:MGI:2442687 +319767 Atp10b MGI:MGI:2442688|Ensembl:ENSMUSG00000055415|Vega:OTTMUSG00000005449 +319770 B930093H17Rik MGI:MGI:2442692 +319772 C130050O18Rik MGI:MGI:2442694|Ensembl:ENSMUSG00000044092|Vega:OTTMUSG00000035853 +319775 E330037M01Rik MGI:MGI:2442705 +319776 Tmem72 MGI:MGI:2442707|Ensembl:ENSMUSG00000048108|Vega:OTTMUSG00000027031 +319780 D030002E05Rik MGI:MGI:2442714 +319781 9530051G07Rik MGI:MGI:2442715|Ensembl:ENSMUSG00000085982 +319782 A730021G18Rik MGI:MGI:2442717 +319783 A730056A06Rik MGI:MGI:2442718|Ensembl:ENSMUSG00000097756 +319784 B830008M09Rik MGI:MGI:2442721 +319786 B930059L03Rik MGI:MGI:2442724 +319788 A830058I18Rik MGI:MGI:2442727 +319791 9430011C21Rik MGI:MGI:2442732 +319796 B930049G02Rik MGI:MGI:2442745 +319798 A730090N16Rik MGI:MGI:2442748 +319800 Slc22a30 MGI:MGI:2442750|Ensembl:ENSMUSG00000052562|Vega:OTTMUSG00000028431 +319801 Tigar MGI:MGI:2442752|Ensembl:ENSMUSG00000038028|Vega:OTTMUSG00000024108 +319803 A430090L17Rik MGI:MGI:2442754 +319804 Glt1d1 MGI:MGI:2442755|Ensembl:ENSMUSG00000049971|Vega:OTTMUSG00000028796 +319805 C130073E24Rik MGI:MGI:2442759 +319806 D630022N01Rik - +319807 Nwd2 MGI:MGI:1920464|Ensembl:ENSMUSG00000090061|Vega:OTTMUSG00000030847 +319810 9530001P21Rik MGI:MGI:2442767 +319812 9430018G01Rik MGI:MGI:2442776 +319814 E130106K03Rik MGI:MGI:2442783 +319815 6030496E16Rik MGI:MGI:2442785 +319816 9630010A21Rik MGI:MGI:2442787 +319817 Rc3h2 MGI:MGI:2442789|Ensembl:ENSMUSG00000075376|Vega:OTTMUSG00000012649 +319818 A930011G23Rik MGI:MGI:2442790|Ensembl:ENSMUSG00000089809|Vega:OTTMUSG00000035958 +319819 4932435O22Rik MGI:MGI:2442791|Ensembl:ENSMUSG00000062391 +319820 B230362B09Rik MGI:MGI:2442793 +319821 9330185G11Rik MGI:MGI:2442795 +319822 Smyd4 MGI:MGI:2442796|Ensembl:ENSMUSG00000018809|Vega:OTTMUSG00000006205 +319823 F630003A18Rik MGI:MGI:2442797 +319826 A130074J08Rik MGI:MGI:2442802 +319829 9330154K18Rik MGI:MGI:2442806 +319830 1500004A13Rik MGI:MGI:2442808 +319832 Tmem229a MGI:MGI:2442812|Ensembl:ENSMUSG00000048022|Vega:OTTMUSG00000033625 +319833 9430072B17Rik MGI:MGI:2442814 +319835 A930104B17Rik MGI:MGI:2442821 +319837 B130016H12Rik MGI:MGI:2442823 +319839 A530020G20Rik MGI:MGI:2442825 +319845 Bbs9 MGI:MGI:2442833|Ensembl:ENSMUSG00000035919|Vega:OTTMUSG00000031157 +319846 A130086G11Rik MGI:MGI:2442834 +319848 Slc17a4 MGI:MGI:2442850|Ensembl:ENSMUSG00000021336|Vega:OTTMUSG00000000588 +319849 Plxna4os1 MGI:MGI:2442851|Ensembl:ENSMUSG00000086763 +319851 A230107O07Rik MGI:MGI:2442853 +319852 9430064G09Rik MGI:MGI:2442856 +319854 A930006I01Rik MGI:MGI:2442861|Ensembl:ENSMUSG00000087278 +319857 A730094K22Rik MGI:MGI:2442864 +319859 E030011O05Rik MGI:MGI:2442867 +319862 E230008O15Rik MGI:MGI:2442870 +319864 D230035N22Rik MGI:MGI:2442872 +319865 E130114P18Rik MGI:MGI:2442873 +319866 D630014O11Rik MGI:MGI:2442874 +319868 9430027J11Rik MGI:MGI:2442881 +319870 9330136K24Rik MGI:MGI:2442883|Ensembl:ENSMUSG00000097781 +319871 4732490B19Rik MGI:MGI:2442884|Ensembl:ENSMUSG00000085421 +319872 9430087C24Rik MGI:MGI:2442885 +319875 Tmprss11b MGI:MGI:2442893|Ensembl:ENSMUSG00000035861|Vega:OTTMUSG00000035106 +319876 Cobll1 MGI:MGI:2442894|Ensembl:ENSMUSG00000034903|Vega:OTTMUSG00000012883 +319878 9630025H16Rik MGI:MGI:2442898 +319880 Tmcc3 MGI:MGI:2442900|Ensembl:ENSMUSG00000020023|Vega:OTTMUSG00000031011 +319885 Zcchc7 MGI:MGI:2442912|Ensembl:ENSMUSG00000035649|Vega:OTTMUSG00000007140 +319886 A430023P06Rik MGI:MGI:2442913 +319887 E030030I06Rik MGI:MGI:2442914|Ensembl:ENSMUSG00000097327 +319888 Oacyl MGI:MGI:2442915|Ensembl:ENSMUSG00000046610|Vega:OTTMUSG00000028243 +319893 A230057D06Rik MGI:MGI:2442922 +319894 E330017L17Rik MGI:MGI:2442924|Ensembl:ENSMUSG00000086369 +319899 Dock6 MGI:MGI:1914789|Ensembl:ENSMUSG00000032198|Vega:OTTMUSG00000062428 +319901 Dsel MGI:MGI:2442948|Ensembl:ENSMUSG00000038702|Vega:OTTMUSG00000048898 +319903 9630013A20Rik MGI:MGI:2442953 +319908 D030005H02Rik MGI:MGI:2442962 +319909 Ism1 MGI:MGI:2442963|Ensembl:ENSMUSG00000074766|Vega:OTTMUSG00000015588 +319910 D030028M11Rik MGI:MGI:2442964 +319911 D830024N08Rik MGI:MGI:2442966 +319913 A630064C07Rik MGI:MGI:2442969 +319915 A830049F12Rik MGI:MGI:2442971 +319916 A730011C13Rik MGI:MGI:2442973 +319917 A630036G19Rik MGI:MGI:2442979 +319919 A230006I23Rik MGI:MGI:2442984 +319922 Vwc2 MGI:MGI:2442987|Ensembl:ENSMUSG00000050830|Vega:OTTMUSG00000005156 +319923 B230119K15Rik MGI:MGI:2442990 +319924 Apba1 MGI:MGI:1860297|Ensembl:ENSMUSG00000024897 +319926 9630021D06Rik MGI:MGI:2442993 +319927 9630050P21Rik MGI:MGI:2442994 +319929 A630076J17Rik MGI:MGI:2442999|Ensembl:ENSMUSG00000094613|Vega:OTTMUSG00000052944 +319930 Ceacam19 MGI:MGI:2443001|Ensembl:ENSMUSG00000049848|Vega:OTTMUSG00000029715 +319931 A330032B11Rik MGI:MGI:2443002|Ensembl:ENSMUSG00000097591 +319933 E230024E03Rik MGI:MGI:2443005 +319934 Sbf2 MGI:MGI:1921831|Ensembl:ENSMUSG00000038371|Vega:OTTMUSG00000036532 +319935 A230059G12Rik MGI:MGI:2443007 +319937 A130091G23Rik MGI:MGI:2443009 +319939 Tns3 MGI:MGI:2443012|Ensembl:ENSMUSG00000020422|Vega:OTTMUSG00000005142 +319940 Sorbs2os MGI:MGI:2443013|Ensembl:ENSMUSG00000085440 +319941 D630030B08Rik MGI:MGI:2443017 +319942 A530016L24Rik MGI:MGI:2443020|Ensembl:ENSMUSG00000043122 +319943 A630074N13Rik MGI:MGI:2443021 +319944 Taf2 MGI:MGI:2443028|Ensembl:ENSMUSG00000037343 +319945 Flad1 MGI:MGI:2443030|Ensembl:ENSMUSG00000042642|Vega:OTTMUSG00000021943 +319949 A130009I22Rik MGI:MGI:2443038 +319951 A230001M10Rik MGI:MGI:2443043|Ensembl:ENSMUSG00000105891 +319953 Ttll1 MGI:MGI:2443047|Ensembl:ENSMUSG00000022442|Vega:OTTMUSG00000023450 +319954 Egfros MGI:MGI:2443051 +319955 Ercc6 MGI:MGI:1100494|Ensembl:ENSMUSG00000054051 +319956 A430068E04Rik MGI:MGI:2443055 +319957 A830061P03Rik MGI:MGI:2443056 +319960 4930513N10Rik MGI:MGI:2443064|Ensembl:ENSMUSG00000074136 +319963 9330119M13Rik MGI:MGI:2443073 +319965 Cc2d1b MGI:MGI:2443076|Ensembl:ENSMUSG00000028582|Vega:OTTMUSG00000008250 +319967 9630019E01Rik MGI:MGI:2443080 +319970 B230323A14Rik MGI:MGI:2443084|Ensembl:ENSMUSG00000097623 +319972 A430110M15Rik MGI:MGI:2443087 +319973 A630077J23Rik MGI:MGI:2443089 +319974 Auts2 MGI:MGI:1919847|Ensembl:ENSMUSG00000029673 +319975 D630014H12Rik MGI:MGI:2443093 +319977 A530079E22Rik MGI:MGI:2443097 +319978 A130099P19Rik MGI:MGI:2443103 +319979 C820005J03Rik MGI:MGI:2443105 +319980 A430027H14Rik MGI:MGI:2443106 +319981 C530044C16Rik MGI:MGI:2443109|Ensembl:ENSMUSG00000107667 +319982 5930430L01Rik MGI:MGI:2443110|Ensembl:ENSMUSG00000106951 +319983 9330111N05Rik MGI:MGI:2443112|Ensembl:ENSMUSG00000097098 +319984 Jph4 MGI:MGI:2443113|Ensembl:ENSMUSG00000022208|Vega:OTTMUSG00000027953 +319986 A130042O14Rik MGI:MGI:2443116 +319988 A130086K04Rik MGI:MGI:2443118 +319990 C730014E05Rik MGI:MGI:2443121 +319991 Kif6 MGI:MGI:1098238|Ensembl:ENSMUSG00000023999|Vega:OTTMUSG00000034551 +319996 Casc4 MGI:MGI:2443129|Ensembl:ENSMUSG00000060227|Vega:OTTMUSG00000015386 +319997 A630001G21Rik MGI:MGI:2443131|Ensembl:ENSMUSG00000052760|Vega:OTTMUSG00000034229 +319998 Tmem198 MGI:MGI:2443133|Ensembl:ENSMUSG00000051703|Vega:OTTMUSG00000019413 +319999 9330169B04Rik MGI:MGI:2443134 +320000 C630016I17Rik MGI:MGI:2443136 +320001 E230015B07Rik MGI:MGI:2443140 +320002 C230083P08Rik MGI:MGI:2443144 +320004 A930002H24Rik MGI:MGI:2443151 +320006 E130107B13Rik MGI:MGI:2443153 +320007 Sidt1 MGI:MGI:2443155|Ensembl:ENSMUSG00000022696|Vega:OTTMUSG00000026174 +320008 A330078L11Rik MGI:MGI:2443158 +320010 D730035F11Rik MGI:MGI:2443161 +320011 Uggt1 MGI:MGI:2443162|Ensembl:ENSMUSG00000037470|Vega:OTTMUSG00000037695 +320014 B930025P03Rik MGI:MGI:2443166|Ensembl:ENSMUSG00000109473 +320015 A130082J08Rik MGI:MGI:2443167 +320016 D030016M11Rik MGI:MGI:2443169 +320019 Ptgs2os MGI:MGI:2443180|Ensembl:ENSMUSG00000097028 +320020 6330415G19Rik MGI:MGI:2443182 +320021 C430042M11Rik MGI:MGI:2443186 +320022 Terb1 MGI:MGI:2443187|Ensembl:ENSMUSG00000052616|Vega:OTTMUSG00000027409 +320023 6720467L15Rik MGI:MGI:2443190 +320024 Nceh1 MGI:MGI:2443191|Ensembl:ENSMUSG00000027698|Vega:OTTMUSG00000028153 +320026 A330076H08Rik MGI:MGI:2443193|Ensembl:ENSMUSG00000109321 +320027 Fstl4 MGI:MGI:2443199|Ensembl:ENSMUSG00000036264|Vega:OTTMUSG00000000041 +320029 C130013I19Rik MGI:MGI:2443201 +320030 B930086L07Rik MGI:MGI:2443202 +320032 C130093G08Rik MGI:MGI:2443208 +320033 A130002D19Rik MGI:MGI:2443209 +320036 D030041H20Rik MGI:MGI:2443213 +320037 6430604M11Rik MGI:MGI:2443216 +320038 Dlx6os1 MGI:MGI:2443217 +320039 A030010E16Rik MGI:MGI:2443218 +320040 Rnf222 MGI:MGI:2443227|Ensembl:ENSMUSG00000046490|Vega:OTTMUSG00000005950 +320044 9530037G02Rik MGI:MGI:2443234 +320046 F730043M19Rik MGI:MGI:2443237|Ensembl:ENSMUSG00000052125 +320047 4833444G19Rik MGI:MGI:2443240 +320051 Exph5 MGI:MGI:2443248|Ensembl:ENSMUSG00000034584|Vega:OTTMUSG00000031816 +320054 9230116N13Rik MGI:MGI:2443255|Ensembl:ENSMUSG00000097403 +320055 F830001A07Rik MGI:MGI:2443257 +320056 6430511E19Rik MGI:MGI:2443259 +320057 A630057N01Rik MGI:MGI:2443263 +320060 B230308N11Rik MGI:MGI:2443268 +320062 E130009g09rik - +320064 D130017N08Rik MGI:MGI:2443273 +320068 E130006N16Rik MGI:MGI:2443277 +320069 3830432H09Rik MGI:MGI:2443278|Ensembl:ENSMUSG00000101731 +320070 D830012I24Rik MGI:MGI:2443279 +320072 A830019L24Rik MGI:MGI:2443282|Ensembl:ENSMUSG00000105923 +320073 D230049E03Rik MGI:MGI:2443283 +320076 C630001G18Rik MGI:MGI:2443303 +320078 Olfml2b MGI:MGI:2443310|Ensembl:ENSMUSG00000038463|Vega:OTTMUSG00000026879 +320080 Zbtb39 MGI:MGI:2443316|Ensembl:ENSMUSG00000044617 +320082 Fbxw21 MGI:MGI:2443323|Ensembl:ENSMUSG00000047237|Vega:OTTMUSG00000027400 +320083 Fbxw16 MGI:MGI:2443324|Ensembl:ENSMUSG00000074062|Vega:OTTMUSG00000051227 +320086 E430022K19Rik MGI:MGI:2443334 +320088 C030034L19Rik MGI:MGI:2444519|Ensembl:ENSMUSG00000097365 +320089 4931433A09Rik MGI:MGI:2443341 +320091 Ano4 MGI:MGI:2443344|Ensembl:ENSMUSG00000035189|Vega:OTTMUSG00000043524 +320092 E030003E18Rik MGI:MGI:2443348 +320094 B930019K04Rik MGI:MGI:2443358 +320095 6430550D23Rik MGI:MGI:2443361|Ensembl:ENSMUSG00000074646|Vega:OTTMUSG00000018447 +320099 BC106179 MGI:MGI:3702726 +320100 Relt MGI:MGI:2443373|Ensembl:ENSMUSG00000008318|Vega:OTTMUSG00000031761 +320102 A730008I21Rik MGI:MGI:2443378 +320103 A730080H06Rik MGI:MGI:2443380 +320104 B130065D12Rik MGI:MGI:2443381 +320105 D030036P13Rik MGI:MGI:2443382 +320106 Slc38a11 MGI:MGI:2443383|Ensembl:ENSMUSG00000061171|Vega:OTTMUSG00000012895 +320107 A630024J24Rik MGI:MGI:2443385 +320108 1110019B24Rik MGI:MGI:2443389 +320110 B230369F24Rik MGI:MGI:2443392 +320111 Prr18 MGI:MGI:2443403|Ensembl:ENSMUSG00000055945 +320113 A430063P04Rik MGI:MGI:2443406 +320114 5930430O07Rik MGI:MGI:2443407 +320116 Fndc9 MGI:MGI:2443410|Ensembl:ENSMUSG00000048721|Vega:OTTMUSG00000007517 +320117 C730049O14Rik MGI:MGI:2443412 +320118 Fbxl13 MGI:MGI:2443416|Ensembl:ENSMUSG00000048520|Vega:OTTMUSG00000025673 +320119 Rps6kc1 MGI:MGI:2443419|Ensembl:ENSMUSG00000089872|Vega:OTTMUSG00000034895 +320120 A130067G02Rik MGI:MGI:2443420 +320121 6720473M08Rik MGI:MGI:2443421 +320122 C230086J09Rik MGI:MGI:2443423 +320123 D130056L21Rik MGI:MGI:2443424 +320124 B930095M22Rik MGI:MGI:2443425 +320125 E130002L11Rik MGI:MGI:2443426 +320127 Dgki MGI:MGI:2443430|Ensembl:ENSMUSG00000038665|Vega:OTTMUSG00000022281 +320129 Grk3 MGI:MGI:87941|Ensembl:ENSMUSG00000042249|Vega:OTTMUSG00000054354 +320132 A230108P19Rik MGI:MGI:2443444|Ensembl:ENSMUSG00000087125 +320133 6030445D17Rik MGI:MGI:2443447 +320135 BC049715 MGI:MGI:3605234|Ensembl:ENSMUSG00000047515|Vega:OTTMUSG00000024469 +320136 4932442A14Rik MGI:MGI:2443453 +320138 A130050O07Rik MGI:MGI:2443458 +320139 Ptpn7 MGI:MGI:2156893|Ensembl:ENSMUSG00000031506|Vega:OTTMUSG00000049797 +320140 B930012P20Rik MGI:MGI:2443462 +320141 9330156P08Rik MGI:MGI:2443463 +320144 C030019G06Rik MGI:MGI:2443468 +320145 Sp8 MGI:MGI:2443471|Ensembl:ENSMUSG00000048562 +320148 B430306N03Rik MGI:MGI:2443478|Ensembl:ENSMUSG00000043740|Vega:OTTMUSG00000028420 +320150 Zdhhc17 MGI:MGI:2445110|Ensembl:ENSMUSG00000035798 +320151 5330432J10Rik MGI:MGI:2443489 +320152 4930412C18Rik MGI:MGI:2443490 +320155 C730002L08Rik MGI:MGI:2443493 +320158 Zmat4 MGI:MGI:2443497|Ensembl:ENSMUSG00000037492|Vega:OTTMUSG00000030997 +320159 Togaram2 MGI:MGI:2443498|Ensembl:ENSMUSG00000045761|Vega:OTTMUSG00000024725 +320162 Cep95 MGI:MGI:2443502|Ensembl:ENSMUSG00000018372|Vega:OTTMUSG00000003582 +320163 4930525G20Rik MGI:MGI:2443505|Ensembl:ENSMUSG00000097276 +320165 Tacc1 MGI:MGI:2443510|Ensembl:ENSMUSG00000065954|Vega:OTTMUSG00000060528 +320166 A430042E23Rik MGI:MGI:2443512 +320167 A330042M18Rik MGI:MGI:2443516 +320168 9630050E16Rik MGI:MGI:2443518 +320170 A130048G24Rik MGI:MGI:2443520 +320171 D130019J16Rik MGI:MGI:2443523 +320172 E230016M11Rik MGI:MGI:2443524|Ensembl:ENSMUSG00000087231 +320173 A630057J21Rik MGI:MGI:2443525 +320174 A830082K12Rik MGI:MGI:2443527 +320176 D930032P07Rik MGI:MGI:2443529|Ensembl:ENSMUSG00000097735 +320178 4921529L05Rik MGI:MGI:2443531|Ensembl:ENSMUSG00000108060 +320179 B230216C01Rik MGI:MGI:2443532 +320181 Fndc7 MGI:MGI:2443535|Ensembl:ENSMUSG00000045326|Vega:OTTMUSG00000007285 +320183 Msrb3 MGI:MGI:2443538|Ensembl:ENSMUSG00000051236|Vega:OTTMUSG00000027726 +320184 Lrrc58 MGI:MGI:2443542|Ensembl:ENSMUSG00000034158|Vega:OTTMUSG00000025723 +320187 E230001N04Rik MGI:MGI:2443549 +320191 Hook3 MGI:MGI:2443554|Ensembl:ENSMUSG00000037234|Vega:OTTMUSG00000033457 +320192 C130092D22Rik MGI:MGI:2443557 +320195 9630041I06Rik MGI:MGI:2443561 +320197 D830046C22Rik MGI:MGI:2443565|Ensembl:ENSMUSG00000044197 +320199 F830004D09Rik MGI:MGI:2443567 +320200 A830080L01Rik MGI:MGI:2443568 +320202 Lefty2 MGI:MGI:2443573|Ensembl:ENSMUSG00000066652|Vega:OTTMUSG00000021474 +320203 C130071C03Rik MGI:MGI:2443574|Ensembl:ENSMUSG00000050334 +320204 Etfbkmt MGI:MGI:2443575|Ensembl:ENSMUSG00000039958|Vega:OTTMUSG00000026169 +320205 A830051L15Rik MGI:MGI:2443585 +320206 A730028G07Rik MGI:MGI:2443587 +320207 Pik3r5 MGI:MGI:2443588|Ensembl:ENSMUSG00000020901|Vega:OTTMUSG00000005944 +320208 Tmem91 MGI:MGI:2443589|Ensembl:ENSMUSG00000061702|Vega:OTTMUSG00000023706 +320209 Ddx11 MGI:MGI:2443590|Ensembl:ENSMUSG00000035842 +320210 A230077H06Rik MGI:MGI:2443592|Ensembl:ENSMUSG00000100600 +320211 A130010C12Rik MGI:MGI:2443594 +320212 C230099D08Rik MGI:MGI:2443595 +320213 Senp5 MGI:MGI:2443596|Ensembl:ENSMUSG00000022772|Vega:OTTMUSG00000025339 +320214 Maats1 MGI:MGI:2443598|Ensembl:ENSMUSG00000022805|Vega:OTTMUSG00000025829 +320215 A130048E20Rik MGI:MGI:2443599 +320216 D230040J21Rik MGI:MGI:2443600 +320222 C130064B19Rik MGI:MGI:2443608 +320224 F830004M19Rik MGI:MGI:2443611 +320225 Catsperg1 MGI:MGI:2443617|Ensembl:ENSMUSG00000049676|Vega:OTTMUSG00000036507 +320226 Ccdc171 MGI:MGI:1922152|Ensembl:ENSMUSG00000052407|Vega:OTTMUSG00000000832 +320227 9330121K16Rik MGI:MGI:2443625 +320229 9530052C20Rik MGI:MGI:2443632 +320230 C130023O10Rik MGI:MGI:2443634 +320233 D030004A10Rik MGI:MGI:2443638 +320234 Ccdc66 MGI:MGI:2443639|Ensembl:ENSMUSG00000046753 +320235 A130012E19Rik MGI:MGI:2443640 +320237 Smim10l2a MGI:MGI:2443645 +320238 A830054O07Rik MGI:MGI:2443649 +320241 E430026H10Rik MGI:MGI:2443652 +320242 9430081I23Rik MGI:MGI:2443653 +320244 Ttll5 MGI:MGI:2443657|Ensembl:ENSMUSG00000012609|Vega:OTTMUSG00000022958 +320246 A730075L09Rik MGI:MGI:2443660 +320247 C030023E24Rik MGI:MGI:2443661 +320249 D130009I18Rik MGI:MGI:2443663 +320253 March3 MGI:MGI:2443667|Ensembl:ENSMUSG00000032656|Vega:OTTMUSG00000016638 +320254 A630084N20Rik MGI:MGI:2443669 +320256 Dlec1 MGI:MGI:2443671|Ensembl:ENSMUSG00000038060|Vega:OTTMUSG00000033511 +320259 A430108C13Rik MGI:MGI:2443683 +320260 A230059L01Rik MGI:MGI:2443688 +320261 A330043J11Rik MGI:MGI:2443689 +320262 A830073O21Rik MGI:MGI:2443692 +320265 Fam19a1 MGI:MGI:2443695|Ensembl:ENSMUSG00000059187|Vega:OTTMUSG00000029712 +320266 D130060J02Rik MGI:MGI:2443698 +320267 Fubp3 MGI:MGI:2443699|Ensembl:ENSMUSG00000026843|Vega:OTTMUSG00000012074 +320268 B930095G15Rik MGI:MGI:2443701 +320270 A230058F20Rik MGI:MGI:2443712 +320271 Scai MGI:MGI:2443716|Ensembl:ENSMUSG00000035236|Vega:OTTMUSG00000012419 +320272 9330162B11Rik MGI:MGI:2443717|Ensembl:ENSMUSG00000103577 +320273 B230208H11Rik MGI:MGI:2443719|Ensembl:ENSMUSG00000097378 +320274 9330209N08Rik MGI:MGI:2443722 +320277 Spef2 MGI:MGI:2443727|Ensembl:ENSMUSG00000072663|Vega:OTTMUSG00000035074 +320279 C630007K24Rik MGI:MGI:2443729 +320281 C230085J04Rik MGI:MGI:2443734 +320286 A630089K24Rik MGI:MGI:2443745 +320289 B830004H01Rik MGI:MGI:2443748 +320290 A830055N07Rik MGI:MGI:2443751 +320292 Rasgef1b MGI:MGI:2443755|Ensembl:ENSMUSG00000089809|Vega:OTTMUSG00000035958 +320295 C920006O11Rik MGI:MGI:2443759|Ensembl:ENSMUSG00000097574 +320297 A830009L08Rik MGI:MGI:2443762|Ensembl:ENSMUSG00000097182 +320299 Iqcb1 MGI:MGI:2443764|Ensembl:ENSMUSG00000022837|Vega:OTTMUSG00000024358 +320301 E530011L22Rik MGI:MGI:2443770 +320302 Glt28d2 MGI:MGI:2443773|Ensembl:ENSMUSG00000031286|Vega:OTTMUSG00000032731 +320304 D130011O08Rik MGI:MGI:2443776 +320305 9530009G21Rik MGI:MGI:2443777 +320307 B230217J21Rik MGI:MGI:2443782 +320308 A130013F12Rik MGI:MGI:2443783 +320309 1520401A03Rik MGI:MGI:2443785|Ensembl:ENSMUSG00000043747|Vega:OTTMUSG00000039807 +320310 C730045O03Rik MGI:MGI:2443786 +320311 Rnf152 MGI:MGI:2443787|Ensembl:ENSMUSG00000047496|Vega:OTTMUSG00000048957 +320312 A430035B10Rik MGI:MGI:2443789|Ensembl:ENSMUSG00000087305 +320313 8030466E21Rik MGI:MGI:2443790 +320314 A230055J12Rik MGI:MGI:2443791 +320315 A330048O09Rik MGI:MGI:2443792|Ensembl:ENSMUSG00000097326 +320316 9330164J24Rik MGI:MGI:2443794 +320317 A830010M09Rik MGI:MGI:2443798 +320321 9430077A04Rik MGI:MGI:2443810 +320322 C230075M21Rik MGI:MGI:2443811 +320323 A930038B10Rik MGI:MGI:2443813 +320324 9630033C03Rik MGI:MGI:2443817 +320327 A430106G13Rik MGI:MGI:2443823 +320328 B130024M06Rik MGI:MGI:2443824 +320329 D830016K09Rik MGI:MGI:2443825 +320330 A730041O05Rik MGI:MGI:2443826 +320331 D230015J17Rik MGI:MGI:2443827 +320332 Hist4h4 MGI:MGI:2448443|Ensembl:ENSMUSG00000096010|Vega:OTTMUSG00000057423 +320333 D830030K20Rik MGI:MGI:2443830|Ensembl:ENSMUSG00000096039 +320334 4930442M18Rik MGI:MGI:2443836 +320342 4931432P07Rik MGI:MGI:2443846 +320343 Lypd6 MGI:MGI:2443848|Ensembl:ENSMUSG00000050447|Vega:OTTMUSG00000012383 +320346 D930044I17Rik MGI:MGI:2443853 +320348 C130051F05Rik MGI:MGI:2443856 +320349 6430543K15Rik MGI:MGI:2443857 +320350 8030450B20Rik MGI:MGI:2443861 +320351 Tmem251 MGI:MGI:2443862|Ensembl:ENSMUSG00000046675 +320352 Lrrc31 MGI:MGI:2443864|Ensembl:ENSMUSG00000074653|Vega:OTTMUSG00000022312 +320353 C230086H14Rik MGI:MGI:2443866 +320354 Grin1os MGI:MGI:2443867 +320355 Lipi MGI:MGI:2443868|Ensembl:ENSMUSG00000032948|Vega:OTTMUSG00000045086 +320358 C430003N24Rik MGI:MGI:2443885 +320359 A730010A20Rik MGI:MGI:2443886 +320360 Ric3 MGI:MGI:2443887|Ensembl:ENSMUSG00000048330|Vega:OTTMUSG00000030290 +320362 9530085L11Rik MGI:MGI:2443889 +320363 D030045P18Rik MGI:MGI:2443891|Ensembl:ENSMUSG00000110874 +320365 Fry MGI:MGI:2443895|Ensembl:ENSMUSG00000056602|Vega:OTTMUSG00000055493 +320367 A530076I17Rik MGI:MGI:2443897 +320370 C230036F13Rik MGI:MGI:2443900 +320372 A430057L12Rik MGI:MGI:2443904 +320374 7530414M10Rik MGI:MGI:2443906 +320376 Bcorl1 MGI:MGI:2443910|Ensembl:ENSMUSG00000036959|Vega:OTTMUSG00000017515 +320377 9330175E14Rik MGI:MGI:2443913 +320378 9630023C09Rik MGI:MGI:2443914 +320379 D630028G08Rik MGI:MGI:2443915 +320380 A230071A22Rik MGI:MGI:2443917 +320382 E030030F06Rik MGI:MGI:2443919 +320383 B230317F23Rik MGI:MGI:2443920 +320384 B230334L07Rik MGI:MGI:2443922 +320385 D330005D02Rik MGI:MGI:2443923 +320387 D930030O05Rik MGI:MGI:2443927 +320389 8030498J20Rik MGI:MGI:2443929 +320390 E330035G20Rik MGI:MGI:2443932|Ensembl:ENSMUSG00000113120 +320391 D930017J03Rik MGI:MGI:2443933 +320392 7030407O06Rik MGI:MGI:2443936 +320394 Cenpt MGI:MGI:2443939|Ensembl:ENSMUSG00000036672|Vega:OTTMUSG00000062059 +320395 C130075A20Rik MGI:MGI:2443940 +320398 Lrig3 MGI:MGI:2443955|Ensembl:ENSMUSG00000020105 +320400 Gm16897 MGI:MGI:4439821|Ensembl:ENSMUSG00000097325 +320403 9930017N22Rik MGI:MGI:2443961 +320404 Itpkb MGI:MGI:109235|Ensembl:ENSMUSG00000038855|Vega:OTTMUSG00000021781 +320405 Cadps2 MGI:MGI:2443963|Ensembl:ENSMUSG00000017978|Vega:OTTMUSG00000022856 +320406 A630009H07Rik MGI:MGI:2443964 +320407 Klri2 MGI:MGI:2443965|Ensembl:ENSMUSG00000043932|Vega:OTTMUSG00000032512 +320408 B230308P20Rik MGI:MGI:2443966 +320411 A730089K16Rik MGI:MGI:2443970 +320414 B930069K15Rik MGI:MGI:2443976 +320415 Gchfr MGI:MGI:2443977|Ensembl:ENSMUSG00000046814|Vega:OTTMUSG00000015763 +320418 4732465E10Rik MGI:MGI:2443985 +320424 B130011K05Rik MGI:MGI:2443995 +320426 A330075M08Rik MGI:MGI:2443997 +320427 A830021K08Rik MGI:MGI:2443998 +320428 A130068F13Rik MGI:MGI:2444001 +320429 Trank1 MGI:MGI:1341834|Ensembl:ENSMUSG00000062296|Vega:OTTMUSG00000052507 +320430 C230073G13Rik MGI:MGI:2444005 +320432 9230110F11Rik MGI:MGI:2444007 +320435 Rinl MGI:MGI:2444024|Ensembl:ENSMUSG00000051735|Vega:OTTMUSG00000059148 +320436 C030009J22Rik MGI:MGI:2444025 +320438 Alg6 MGI:MGI:2444031|Ensembl:ENSMUSG00000073792|Vega:OTTMUSG00000007982 +320440 9530091C08Rik MGI:MGI:2444034 +320441 A130022F02Rik MGI:MGI:2444035 +320442 A730098A19Rik MGI:MGI:2444037 +320444 D030059C06Rik MGI:MGI:2444039 +320449 A730004F24Rik MGI:MGI:2444046|Ensembl:ENSMUSG00000103690 +320452 P4ha3 MGI:MGI:2444049|Ensembl:ENSMUSG00000051048|Vega:OTTMUSG00000030962 +320453 Dlx4os MGI:MGI:2444057|Ensembl:ENSMUSG00000086552 +320454 Tmprss11g MGI:MGI:2444058|Ensembl:ENSMUSG00000079451|Vega:OTTMUSG00000033619 +320455 A630036H22Rik MGI:MGI:2444062 +320456 B330016D10Rik MGI:MGI:2444063 +320460 Vwc2l MGI:MGI:2444069|Ensembl:ENSMUSG00000045648|Vega:OTTMUSG00000026625 +320461 D430033H22Rik MGI:MGI:2444071 +320462 B930098A02Rik MGI:MGI:2444073 +320463 F630111L10Rik MGI:MGI:2444074|Ensembl:ENSMUSG00000036381 +320466 A230103J11Rik MGI:MGI:2444082|Ensembl:ENSMUSG00000087026 +320469 9930014A18Rik MGI:MGI:2444091 +320471 D230022J07Rik MGI:MGI:2444095 +320472 Ppm1e MGI:MGI:2444096|Ensembl:ENSMUSG00000046442|Vega:OTTMUSG00000001239 +320473 Heatr5b MGI:MGI:2444098|Ensembl:ENSMUSG00000039414 +320474 E030042O20Rik MGI:MGI:2444099 +320475 A530082H02Rik MGI:MGI:2444100 +320478 Sox2ot MGI:MGI:2444112|Ensembl:ENSMUSG00000105265 +320479 C330024D21Rik MGI:MGI:2444116|Ensembl:ENSMUSG00000107385 +320480 6430537K16Rik MGI:MGI:2444124 +320482 Nron MGI:MGI:2444126|Ensembl:ENSMUSG00000086484 +320483 E130314K07Rik MGI:MGI:2444127 +320484 Rasal3 MGI:MGI:2444128|Ensembl:ENSMUSG00000052142|Vega:OTTMUSG00000034066 +320485 B230312C02Rik MGI:MGI:2444130 +320486 A430078I02Rik MGI:MGI:2444132|Ensembl:ENSMUSG00000085589 +320487 Heatr5a MGI:MGI:2444133|Ensembl:ENSMUSG00000035181 +320488 D130039L10Rik MGI:MGI:2444134 +320489 C530050E15Rik MGI:MGI:2444135 +320491 A830054O04Rik MGI:MGI:2444139 +320492 A830018L16Rik MGI:MGI:2444149|Ensembl:ENSMUSG00000057715|Vega:OTTMUSG00000033915 +320494 9330162L04Rik MGI:MGI:2444158 +320495 Ipcef1 MGI:MGI:2444159|Ensembl:ENSMUSG00000064065|Vega:OTTMUSG00000022995 +320496 C230076A16Rik MGI:MGI:2444160 +320497 A630065K11Rik MGI:MGI:2444161 +320500 Tmem215 MGI:MGI:2444167|Ensembl:ENSMUSG00000046593|Vega:OTTMUSG00000006582 +320502 Lmod3 MGI:MGI:2444169|Ensembl:ENSMUSG00000044086|Vega:OTTMUSG00000057822 +320505 A530083M17Rik MGI:MGI:2444172 +320506 Lmbrd2 MGI:MGI:2444173|Ensembl:ENSMUSG00000039704 +320507 D930015M05Rik MGI:MGI:3612068|Ensembl:ENSMUSG00000084781 +320508 Cachd1 MGI:MGI:2444177|Ensembl:ENSMUSG00000028532|Vega:OTTMUSG00000008016 +320509 9930022D16Rik MGI:MGI:2444178 +320512 D930014O13Rik MGI:MGI:2444182 +320513 3222401L13Rik MGI:MGI:2444186 +320514 A430028G04Rik MGI:MGI:2444187 +320515 A730094L24Rik MGI:MGI:2444189 +320516 A730060N03Rik MGI:MGI:2444190 +320522 Bhlha9 MGI:MGI:2444198|Ensembl:ENSMUSG00000044243|Vega:OTTMUSG00000006236 +320525 A230054N11Rik MGI:MGI:2444204 +320526 A830080H07Rik MGI:MGI:2444205 +320528 Vps13c MGI:MGI:2444207|Ensembl:ENSMUSG00000035284|Vega:OTTMUSG00000062686 +320529 B130063F10Rik MGI:MGI:2444208 +320531 D030074K08Rik MGI:MGI:2444217 +320534 Tmem104 MGI:MGI:2444222|Ensembl:ENSMUSG00000045980|Vega:OTTMUSG00000003663 +320538 Ubn2 MGI:MGI:2444236|Ensembl:ENSMUSG00000038538|Vega:OTTMUSG00000034252 +320539 9330159H11Rik MGI:MGI:2444237 +320540 B330018G23Rik MGI:MGI:2444238 +320541 Slc35e2 MGI:MGI:2444240|Ensembl:ENSMUSG00000042202|Vega:OTTMUSG00000010725 +320544 D930030I03Rik MGI:MGI:2444245 +320545 A430019L02Rik MGI:MGI:2444246 +320546 A130075O10Rik MGI:MGI:2444247 +320547 D630023O14Rik MGI:MGI:2444249 +320549 D5Ertd577e MGI:MGI:1261918|Ensembl:ENSMUSG00000070677|Vega:OTTMUSG00000055673 +320550 5930405F01Rik MGI:MGI:2444252 +320551 B430209F14Rik MGI:MGI:2444254 +320552 D930019F10Rik MGI:MGI:2444255 +320554 Tcp11l1 MGI:MGI:2444263|Ensembl:ENSMUSG00000027175|Vega:OTTMUSG00000014956 +320556 C230085N15Rik MGI:MGI:2444267 +320557 Fam169a MGI:MGI:2444268|Ensembl:ENSMUSG00000041817 +320558 Sycp2 MGI:MGI:1933281|Ensembl:ENSMUSG00000060445|Vega:OTTMUSG00000016353 +320560 Dennd5b MGI:MGI:2444273|Ensembl:ENSMUSG00000030313|Vega:OTTMUSG00000023280 +320563 Islr2 MGI:MGI:2444277|Ensembl:ENSMUSG00000051243|Vega:OTTMUSG00000063235 +320564 A530054B12Rik MGI:MGI:2444278 +320565 A730093K11Rik MGI:MGI:2444279 +320566 A830029E22Rik MGI:MGI:2444280|Ensembl:ENSMUSG00000103695 +320569 A130023I24Rik MGI:MGI:2444285 +320571 Atp8b5 MGI:MGI:2444287|Ensembl:ENSMUSG00000028457|Vega:OTTMUSG00000006784 +320573 C130024J02Rik MGI:MGI:2444290 +320575 C230057H02Rik MGI:MGI:2444301 +320579 A730032A03Rik MGI:MGI:2444311 +320580 A930025A13Rik MGI:MGI:2444313 +320581 Idi2 MGI:MGI:2444315|Ensembl:ENSMUSG00000033520|Vega:OTTMUSG00000046928 +320586 A630089N07Rik MGI:MGI:2444323 +320587 Tmem88b MGI:MGI:2444329|Ensembl:ENSMUSG00000073680|Vega:OTTMUSG00000010852 +320588 C330006P03Rik MGI:MGI:2444330 +320589 9530020O07Rik MGI:MGI:2444331 +320590 Svopl MGI:MGI:2444335|Ensembl:ENSMUSG00000029830|Vega:OTTMUSG00000024664 +320591 9630026C02Rik MGI:MGI:2444337 +320592 D130076A03Rik MGI:MGI:2444338 +320593 A230051N06Rik MGI:MGI:2444339 +320595 Phf8 MGI:MGI:2444341|Ensembl:ENSMUSG00000041229|Vega:OTTMUSG00000017224 +320596 A830039H05Rik MGI:MGI:2444344 +320597 6330444A18Rik MGI:MGI:2444347 +320600 A930104D05Rik MGI:MGI:2444352 +320604 Ccdc169 MGI:MGI:2444356|Ensembl:ENSMUSG00000048655|Vega:OTTMUSG00000026682 +320606 3632454L22Rik MGI:MGI:2444359|Ensembl:ENSMUSG00000089759 +320608 D930023I05Rik MGI:MGI:2444362 +320609 Strip2 MGI:MGI:2444363|Ensembl:ENSMUSG00000039629|Vega:OTTMUSG00000013735 +320613 Spag17os MGI:MGI:2444368 +320614 A330033J07Rik MGI:MGI:2444369|Ensembl:ENSMUSG00000097622 +320615 Dopey1 MGI:MGI:1289294|Ensembl:ENSMUSG00000034973|Vega:OTTMUSG00000045042 +320616 B130006D01Rik MGI:MGI:2444371|Ensembl:ENSMUSG00000075596 +320620 E430021H15Rik MGI:MGI:2444377 +320621 D830044D21Rik MGI:MGI:2444378 +320622 B930068K11Rik MGI:MGI:2444379 +320624 4930474G06Rik MGI:MGI:2444381 +320626 9230105E05Rik MGI:MGI:2444388|Ensembl:ENSMUSG00000090191 +320627 A330053N03Rik MGI:MGI:2444390 +320628 A130038J17Rik MGI:MGI:2444394 +320631 Abca15 MGI:MGI:2388709|Ensembl:ENSMUSG00000054746|Vega:OTTMUSG00000029806 +320632 Snrnp200 MGI:MGI:2444401|Ensembl:ENSMUSG00000003660|Vega:OTTMUSG00000016015 +320633 Zbtb26 MGI:MGI:2444402|Ensembl:ENSMUSG00000050714|Vega:OTTMUSG00000012648 +320634 Ocrl MGI:MGI:109589|Ensembl:ENSMUSG00000001173|Vega:OTTMUSG00000017566 +320635 Cyb5r2 MGI:MGI:2444415|Ensembl:ENSMUSG00000048065|Vega:OTTMUSG00000059945 +320637 C130089K02Rik MGI:MGI:2444420 +320638 A730006G06Rik MGI:MGI:2444422 +320640 Skint4 MGI:MGI:2444425|Ensembl:ENSMUSG00000055960|Vega:OTTMUSG00000008537 +320641 E130120C16Rik MGI:MGI:2444427 +320642 A630066F11Rik MGI:MGI:2444428 +320646 6030439D06Rik MGI:MGI:2444447 +320648 B630006K09Rik MGI:MGI:2444452 +320649 9330187G09Rik MGI:MGI:2444454 +320650 9530056K15Rik MGI:MGI:2444456 +320653 A630078F23Rik MGI:MGI:2444459 +320654 E330024J20Rik MGI:MGI:2444460 +320655 Pgap3 MGI:MGI:2444461|Ensembl:ENSMUSG00000038208|Vega:OTTMUSG00000002715 +320656 C230071H17Rik MGI:MGI:2444463 +320657 C430019F06Rik MGI:MGI:2444468 +320659 A630031M04Rik MGI:MGI:2444470 +320661 D5Ertd579e MGI:MGI:1261849|Ensembl:ENSMUSG00000029190|Vega:OTTMUSG00000028039 +320662 Casc1 MGI:MGI:2444480|Ensembl:ENSMUSG00000043541|Vega:OTTMUSG00000023460 +320664 Cass4 MGI:MGI:2444482|Ensembl:ENSMUSG00000074570|Vega:OTTMUSG00000016152 +320665 D430030G11Rik MGI:MGI:2444492 +320668 B930042K01Rik MGI:MGI:2444497 +320669 A230092J17Rik MGI:MGI:2444498 +320671 D130079A08Rik MGI:MGI:2444500 +320672 C230073O14Rik MGI:MGI:2444502 +320674 4921534A09Rik MGI:MGI:2444504 +320678 Iffo1 MGI:MGI:2444516|Ensembl:ENSMUSG00000038271|Vega:OTTMUSG00000027099 +320679 Samd12 MGI:MGI:2444518|Ensembl:ENSMUSG00000058656|Vega:OTTMUSG00000019492 +320682 9330174C13Rik MGI:MGI:2444523 +320683 Zfp629 MGI:MGI:2444524|Ensembl:ENSMUSG00000045639|Vega:OTTMUSG00000028743 +320684 9630028H03Rik MGI:MGI:2444526|Ensembl:ENSMUSG00000085631 +320685 Dctd MGI:MGI:2444529|Ensembl:ENSMUSG00000031562|Vega:OTTMUSG00000037722 +320688 D930030F02Rik MGI:MGI:2444533 +320691 C230088H06Rik MGI:MGI:2444536 +320692 9430037G07Rik MGI:MGI:2444544|Ensembl:ENSMUSG00000097073 +320693 C130021H21Rik MGI:MGI:2444547 +320694 C330003G01Rik MGI:MGI:2444548 +320696 Ccdc158 MGI:MGI:2444555|Ensembl:ENSMUSG00000050050|Vega:OTTMUSG00000024834 +320698 C530042K13Rik MGI:MGI:2444558 +320700 A930033H14Rik MGI:MGI:2444562|Ensembl:ENSMUSG00000090622|Vega:OTTMUSG00000035398 +320701 Fam19a4 MGI:MGI:2444563|Ensembl:ENSMUSG00000046500|Vega:OTTMUSG00000057697 +320702 A730046G19Rik MGI:MGI:2444569 +320703 B230340J04Rik MGI:MGI:2444570 +320704 A130001G05Rik MGI:MGI:2444571 +320705 Bend6 MGI:MGI:2444572|Ensembl:ENSMUSG00000042182|Vega:OTTMUSG00000021502 +320706 Soga1 MGI:MGI:2444575|Ensembl:ENSMUSG00000055485|Vega:OTTMUSG00000016168 +320707 Atp2b3 MGI:MGI:1347353|Ensembl:ENSMUSG00000031376|Vega:OTTMUSG00000017670 +320709 Tmem117 MGI:MGI:2444580|Ensembl:ENSMUSG00000063296 +320712 Abi3bp MGI:MGI:2444583|Ensembl:ENSMUSG00000035258 +320713 Mysm1 MGI:MGI:2444584|Ensembl:ENSMUSG00000062627|Vega:OTTMUSG00000007999 +320714 Trappc11 MGI:MGI:2444585|Ensembl:ENSMUSG00000038102|Vega:OTTMUSG00000028479 +320715 C530043K16Rik MGI:MGI:2444587 +320716 D430047D06Rik MGI:MGI:2444592 +320717 Pptc7 MGI:MGI:2444593|Ensembl:ENSMUSG00000038582|Vega:OTTMUSG00000026703 +320718 Slc26a9 MGI:MGI:2444594|Ensembl:ENSMUSG00000042268|Vega:OTTMUSG00000021566 +320719 6030443J06Rik MGI:MGI:2444595|Ensembl:ENSMUSG00000097207 +320720 Fastkd1 MGI:MGI:2444596|Ensembl:ENSMUSG00000027086|Vega:OTTMUSG00000013008 +320722 Akain1 MGI:MGI:2444600|Ensembl:ENSMUSG00000091636 +320723 B230220B15Rik MGI:MGI:2444601 +320727 Ipo8 MGI:MGI:2444611|Ensembl:ENSMUSG00000040029|Vega:OTTMUSG00000026161 +320731 A530030E21Rik MGI:MGI:2444617 +320733 4930502C15Rik MGI:MGI:2444621 +320734 C920008G01Rik MGI:MGI:2444626|IMGT/GENE-DB:TRAV7D-6 +320736 Vstm4 MGI:MGI:2444633|Ensembl:ENSMUSG00000050666|Vega:OTTMUSG00000015245 +320737 4732416N19Rik MGI:MGI:2444634 +320739 6530403H02Rik MGI:MGI:2444638 +320740 D830012I16Rik MGI:MGI:2444640 +320742 A230072C01Rik MGI:MGI:2444644 +320744 A130049L09Rik MGI:MGI:2444647 +320746 5330437M03Rik MGI:MGI:2444650 +320747 Lingo4 MGI:MGI:2444651|Ensembl:ENSMUSG00000044505|Vega:OTTMUSG00000035252 +320748 B930032E21Rik MGI:MGI:2444653 +320749 D630041G03Rik MGI:MGI:2444655 +320751 D830014E11Rik MGI:MGI:2444658 +320752 Dpy19l2 MGI:MGI:2444662|Ensembl:ENSMUSG00000085576|Vega:OTTMUSG00000062543 +320754 E430034C17Rik MGI:MGI:2444665 +320756 9330155M09Rik MGI:MGI:2444670 +320757 A630052C17Rik MGI:MGI:2444673 +320760 6720464F23Rik MGI:MGI:2444677 +320761 D630008O14Rik MGI:MGI:3698880 +320763 A430034D21Rik MGI:MGI:2444685 +320764 9930032E11Rik MGI:MGI:2444687 +320765 9630045H20Rik MGI:MGI:2444689 +320766 E030022I16Rik MGI:MGI:2444690 +320769 Prdx6b MGI:MGI:1336888|Ensembl:ENSMUSG00000050114|Vega:OTTMUSG00000013338 +320770 A630072M18Rik MGI:MGI:2444702|Ensembl:ENSMUSG00000101013 +320771 C030040A22Rik MGI:MGI:2444705 +320772 Mdga2 MGI:MGI:2444706|Ensembl:ENSMUSG00000034912|Vega:OTTMUSG00000042300 +320775 B230319C09Rik MGI:MGI:2444713|Ensembl:ENSMUSG00000051844 +320779 D230002P11Rik MGI:MGI:2444718 +320780 9430029E18Rik MGI:MGI:2444722 +320782 Tmem154 MGI:MGI:2444725|Ensembl:ENSMUSG00000056498|Vega:OTTMUSG00000022062 +320783 C130083B21Rik MGI:MGI:2444726 +320784 C230072F16Rik MGI:MGI:2444727|Ensembl:ENSMUSG00000112121 +320787 9130221L21Rik MGI:MGI:2444742 +320788 9930104M19Rik MGI:MGI:2444743 +320790 Chd7 MGI:MGI:2444748|Ensembl:ENSMUSG00000041235|Vega:OTTMUSG00000004417 +320791 A130071D04Rik MGI:MGI:2444749 +320793 A330072L02Rik MGI:MGI:2444754 +320794 C130034I24Rik MGI:MGI:2444755 +320795 Pkn1 MGI:MGI:108022|Ensembl:ENSMUSG00000057672|Vega:OTTMUSG00000025931 +320796 C030044O21Rik MGI:MGI:2444758 +320797 F830005D05Rik MGI:MGI:2444759 +320798 4831440D22Rik MGI:MGI:2444771 +320799 Zhx3 MGI:MGI:2444772|Ensembl:ENSMUSG00000035877|Vega:OTTMUSG00000001048 +320800 9230112E08Rik MGI:MGI:2444774 +320801 A630035G10Rik MGI:MGI:2444775 +320802 Ifitm10 MGI:MGI:2444776|Ensembl:ENSMUSG00000045777|Vega:OTTMUSG00000018785 +320804 5830444F18Rik MGI:MGI:2444780 +320805 C330018A13Rik MGI:MGI:2444781 +320806 Gfm2 MGI:MGI:2444783|Ensembl:ENSMUSG00000021666|Vega:OTTMUSG00000034272 +320808 Dcaf5 MGI:MGI:2444785|Ensembl:ENSMUSG00000049106 +320809 A230056K03Rik MGI:MGI:2444787 +320810 E030026E10Rik MGI:MGI:2444788 +320811 9430034N14Rik MGI:MGI:2444791 +320812 C230071I02Rik MGI:MGI:2444792 +320813 A630078A22Rik MGI:MGI:2444793 +320816 Ankrd16 MGI:MGI:2444796|Ensembl:ENSMUSG00000047909|Vega:OTTMUSG00000011295 +320817 Atad2b MGI:MGI:2444798|Ensembl:ENSMUSG00000052812 +320821 A130022D17Rik MGI:MGI:2444806 +320822 4732417M03Rik MGI:MGI:2444808 +320825 Samd5 MGI:MGI:2444815|Ensembl:ENSMUSG00000060487|Vega:OTTMUSG00000037128 +320826 8030448K23Rik MGI:MGI:2444816 +320827 C530008M17Rik MGI:MGI:2444817|Ensembl:ENSMUSG00000036377|Vega:OTTMUSG00000026511 +320829 C430014B12Rik MGI:MGI:2444820 +320832 Sirpb1a MGI:MGI:2444824|Ensembl:ENSMUSG00000095788|Vega:OTTMUSG00000052297 +320834 D130067P18Rik MGI:MGI:2444827 +320839 9330168M11Rik MGI:MGI:2444836 +320840 Negr1 MGI:MGI:2444846|Ensembl:ENSMUSG00000040037|Vega:OTTMUSG00000024007 +320842 C230035I16Rik MGI:MGI:2444850|Ensembl:ENSMUSG00000085024 +320844 Amigo3 MGI:MGI:2444854|Ensembl:ENSMUSG00000032593|Vega:OTTMUSG00000016524 +320845 A230056P14Rik MGI:MGI:2444856 +320846 A530058N18Rik MGI:MGI:2444858|Ensembl:ENSMUSG00000087694 +320847 D330040H18Rik MGI:MGI:2444859 +320848 6030446J10Rik MGI:MGI:2444860 +320850 9430047L24Rik MGI:MGI:2444864 +320851 D130012G24Rik MGI:MGI:2444865 +320854 9030203C11Rik MGI:MGI:2444876 +320855 A230061C15Rik MGI:MGI:2444877 +320858 L3mbtl4 MGI:MGI:2444889|Ensembl:ENSMUSG00000041565|Vega:OTTMUSG00000028472 +320859 A230077L10Rik MGI:MGI:2444892 +320860 B130021B11Rik MGI:MGI:2444894 +320862 A730054J21Rik MGI:MGI:2444908 +320863 A630083H20Rik MGI:MGI:2444909 +320864 Krt26 MGI:MGI:2444913|Ensembl:ENSMUSG00000075570|Vega:OTTMUSG00000006449 +320865 Cdh18 MGI:MGI:1344366|Ensembl:ENSMUSG00000040420|Vega:OTTMUSG00000036412 +320866 C030015D19Rik MGI:MGI:2444915 +320869 Spata33 MGI:MGI:2444920|Ensembl:ENSMUSG00000048478|Vega:OTTMUSG00000061952 +320870 E330013P08Rik MGI:MGI:2444924 +320871 B230206H07Rik MGI:MGI:2444929|Ensembl:ENSMUSG00000086844 +320872 Arhgap15os MGI:MGI:2444930|Ensembl:ENSMUSG00000085089 +320873 Cdh10 MGI:MGI:107436|Ensembl:ENSMUSG00000022321|Vega:OTTMUSG00000039788 +320874 D930030D11Rik MGI:MGI:2444932 +320876 D930002L09Rik MGI:MGI:2444936 +320877 D330023I04Rik MGI:MGI:2444937 +320878 Mical2 MGI:MGI:2444947|Ensembl:ENSMUSG00000038244|Vega:OTTMUSG00000023847 +320879 B230217O12Rik MGI:MGI:2444948|Ensembl:ENSMUSG00000097785 +320880 8030493G06Rik MGI:MGI:2444953 +320885 B930008F14Rik MGI:MGI:2444964 +320886 A630006J10Rik MGI:MGI:2444967 +320888 E030024I16Rik MGI:MGI:2444971 +320889 C230079E05Rik MGI:MGI:2444972 +320891 C130070B15Rik MGI:MGI:2444974 +320893 6430562O15Rik MGI:MGI:2444982 +320896 C330020E22Rik MGI:MGI:2444986 +320897 8030431J09Rik MGI:MGI:2444987 +320898 Trav3-3 MGI:MGI:3702145|IMGT/GENE-DB:TRAV3-3 +320899 A430110C17Rik MGI:MGI:2444994 +320904 D630012G11Rik MGI:MGI:2445002 +320905 A130026F07Rik MGI:MGI:2445012 +320907 B430105G09Rik MGI:MGI:2445016 +320908 E430014B02Rik MGI:MGI:2445017 +320910 Itgb8 MGI:MGI:1338035|Ensembl:ENSMUSG00000025321|Vega:OTTMUSG00000026449 +320911 D830024F11Rik MGI:MGI:2445023 +320912 A330041D05Rik MGI:MGI:2445024 +320913 Trdv2-2 MGI:MGI:4819748|IMGT/GENE-DB:TRDV2-2 +320914 A630044M17Rik MGI:MGI:2445026 +320916 Wscd2 MGI:MGI:2445030|Ensembl:ENSMUSG00000063430|Vega:OTTMUSG00000029483 +320919 A230107N01Rik MGI:MGI:2445042|Ensembl:ENSMUSG00000097292 +320920 Parvaos MGI:MGI:2445046 +320922 A230004M16Rik MGI:MGI:2445050 +320923 Map7d3 MGI:MGI:2445051|Ensembl:ENSMUSG00000067878|Vega:OTTMUSG00000017710 +320924 Ccbe1 MGI:MGI:2445053|Ensembl:ENSMUSG00000046318|Vega:OTTMUSG00000028218 +320926 C730029A08Rik MGI:MGI:2445056 +320927 6720474J12Rik MGI:MGI:2445057 +320929 4732460I02Rik MGI:MGI:2445061 +320930 B930028L11Rik MGI:MGI:2445063 +320933 D230017M19Rik MGI:MGI:2445071 +320936 E430024P14Rik MGI:MGI:2445079 +320937 E430014L09Rik MGI:MGI:2445080 +320938 Tnpo3 MGI:MGI:1196412|Ensembl:ENSMUSG00000012535|Vega:OTTMUSG00000035859 +320939 5930403L14Rik MGI:MGI:2445083 +320940 Atp11c MGI:MGI:1859661|Ensembl:ENSMUSG00000062949|Vega:OTTMUSG00000017557 +320942 A730061H03Rik MGI:MGI:2445099 +320943 B230213L16Rik MGI:MGI:2445101 +320946 A930035D04Rik MGI:MGI:2445106 +320947 B930082K07Rik MGI:MGI:2445108 +320949 D830039M14Rik MGI:MGI:2445111 +320950 9330104G04Rik MGI:MGI:2445112|Ensembl:ENSMUSG00000097842 +320951 Pisd MGI:MGI:2445114|Ensembl:ENSMUSG00000023452|Vega:OTTMUSG00000021306 +320952 A730013G03Rik MGI:MGI:2445118 +320955 9430088B20Rik MGI:MGI:2445127 +320959 A230048O21Rik MGI:MGI:2445134 +320961 A630026N12Rik MGI:MGI:2445136 +320962 B130040O20Rik MGI:MGI:2445139 +320964 B230378D16Rik MGI:MGI:2445142 +320965 4831440E17Rik MGI:MGI:2445144 +320966 B530045E10Rik MGI:MGI:2445145 +320967 B930046M08Rik MGI:MGI:2445146 +320971 4832406H04Rik MGI:MGI:2445150 +320972 D130020G16Rik MGI:MGI:2445151 +320973 D330023K18Rik MGI:MGI:2445152 +320974 Lrrn4 MGI:MGI:2445154|Ensembl:ENSMUSG00000043110|Vega:OTTMUSG00000015655 +320975 D330050G23Rik MGI:MGI:2445155|Ensembl:ENSMUSG00000085316 +320977 A330023F24Rik MGI:MGI:2443958|Ensembl:ENSMUSG00000096929 +320981 Enpp6 MGI:MGI:2445171|Ensembl:ENSMUSG00000038173|Vega:OTTMUSG00000030565 +320982 Arl4c MGI:MGI:2445172|Ensembl:ENSMUSG00000049866|Vega:OTTMUSG00000028785 +320983 B130019D13Rik MGI:MGI:2445174 +320984 4932442G11Rik MGI:MGI:2445180 +320986 A630040H13Rik MGI:MGI:2445184 +320991 C230031I18Rik MGI:MGI:2445192 +320992 9430083M05Rik MGI:MGI:2445197 +320993 E030003N13Rik MGI:MGI:2445199 +320995 Rfx6 MGI:MGI:2445208|Ensembl:ENSMUSG00000019900 +320996 D130047N11Rik MGI:MGI:2445209 +320997 Cyp4f39 MGI:MGI:2445210|Ensembl:ENSMUSG00000061126 +320998 E230034D01Rik MGI:MGI:2445211 +320999 9530019H20Rik MGI:MGI:2445212 +321000 Lrif1 MGI:MGI:2445214|Ensembl:ENSMUSG00000056260|Vega:OTTMUSG00000032748 +321001 C230021G24Rik MGI:MGI:3697434 +321002 B930063P07Rik MGI:MGI:2445216 +321003 Xpnpep3 MGI:MGI:2445217|Ensembl:ENSMUSG00000022401|Vega:OTTMUSG00000035640 +321004 9330197I21Rik MGI:MGI:2445218 +321006 Vprbp MGI:MGI:2445220|Ensembl:ENSMUSG00000040325|Vega:OTTMUSG00000032620 +321007 Serac1 MGI:MGI:2447813|Ensembl:ENSMUSG00000015659|Vega:OTTMUSG00000024050 +321008 6330408A02Rik MGI:MGI:2447816|Ensembl:ENSMUSG00000070814 +321010 1700006J14Rik MGI:MGI:2447818 +321013 4930442P19Rik MGI:MGI:2447822 +321014 4930473A02Rik MGI:MGI:2447823|Ensembl:ENSMUSG00000060029 +321015 5330439B14Rik MGI:MGI:2447824|Ensembl:ENSMUSG00000104234 +321016 Gm10817 MGI:MGI:3704489 +321017 9230116L04Rik MGI:MGI:2447826|Ensembl:ENSMUSG00000112489 +321018 Serpina4-ps1 MGI:MGI:2448363 +321019 Gpr183 MGI:MGI:2442034|Ensembl:ENSMUSG00000051212 +321020 Fpr-rs6 MGI:MGI:2448176|Ensembl:ENSMUSG00000071275|Vega:OTTMUSG00000039772 +321021 Fpr-rs7 MGI:MGI:2448177|Ensembl:ENSMUSG00000071276|Vega:OTTMUSG00000039771 +321022 Cdv3 MGI:MGI:2448759|Ensembl:ENSMUSG00000032803|Vega:OTTMUSG00000048458 +326618 Tpm4 MGI:MGI:2449202|Ensembl:ENSMUSG00000031799|Vega:OTTMUSG00000022549 +326619 Hist1h4a MGI:MGI:2448419|Ensembl:ENSMUSG00000060093|Vega:OTTMUSG00000000577 +326620 Hist1h4b MGI:MGI:2448420|Ensembl:ENSMUSG00000069266|Vega:OTTMUSG00000000579 +326622 Upf2 MGI:MGI:2449307|Ensembl:ENSMUSG00000043241|Vega:OTTMUSG00000011208 +326623 Tnfsf15 MGI:MGI:2180140|Ensembl:ENSMUSG00000050395|Vega:OTTMUSG00000000303 +327655 Ppip5k1 MGI:MGI:2443281|Ensembl:ENSMUSG00000033526|Vega:OTTMUSG00000015262 +327743 Wisp3 MGI:MGI:2685581|Ensembl:ENSMUSG00000062074|Vega:OTTMUSG00000063415 +327744 E130307A14Rik MGI:MGI:3036287|Ensembl:ENSMUSG00000087177 +327747 Mettl24 MGI:MGI:3045338|Ensembl:ENSMUSG00000045555|Vega:OTTMUSG00000027975 +327749 Gm5079 MGI:MGI:3779452 +327760 Gm20611 MGI:MGI:5313058|Ensembl:ENSMUSG00000093568 +327762 Dna2 MGI:MGI:2443732|Ensembl:ENSMUSG00000036875|Vega:OTTMUSG00000030825 +327766 Tmem26 MGI:MGI:2143537|Ensembl:ENSMUSG00000060044 +327767 Gm5080 MGI:MGI:3648383 +327768 A330049N07Rik MGI:MGI:3041175|Ensembl:ENSMUSG00000111994 +327780 4933439G19Rik MGI:MGI:3041160 +327781 A130033P14 - +327799 Usp44 MGI:MGI:3045318|Ensembl:ENSMUSG00000020020|Vega:OTTMUSG00000063919 +327800 B930071A02 - +327812 Gm15663 MGI:MGI:3783105|Ensembl:ENSMUSG00000085282 +327814 Ppfia2 MGI:MGI:2443834|Ensembl:ENSMUSG00000053825 +327824 5330438D12Rik MGI:MGI:3026931 +327826 Frs2 MGI:MGI:1100860|Ensembl:ENSMUSG00000020170 +327837 B930054O08 - +327857 A330087I24 - +327860 Gm11961 MGI:MGI:3652303|Ensembl:ENSMUSG00000056288 +327871 Gm12017 MGI:MGI:3651377 +327872 Gm12018 MGI:MGI:3651187|Ensembl:ENSMUSG00000085453 +327885 C030046G05 - +327900 Ubtd2 MGI:MGI:2444752|Ensembl:ENSMUSG00000044949|Vega:OTTMUSG00000005379 +327901 4831410D14 - +327939 Gm12273 MGI:MGI:3650148|Ensembl:ENSMUSG00000084805 +327942 Pigl MGI:MGI:2681271|Ensembl:ENSMUSG00000014245|Vega:OTTMUSG00000005858 +327946 Gm12295 MGI:MGI:3650535|Ensembl:ENSMUSG00000085162 +327951 Cyb5d1 MGI:MGI:2685586|Ensembl:ENSMUSG00000044795|Vega:OTTMUSG00000005976 +327954 Dnah2 MGI:MGI:107731|Ensembl:ENSMUSG00000005237|Vega:OTTMUSG00000005984 +327956 Vmo1 MGI:MGI:2685587|Ensembl:ENSMUSG00000020830|Vega:OTTMUSG00000006061 +327957 Scimp MGI:MGI:3610314|Ensembl:ENSMUSG00000057135|Vega:OTTMUSG00000006065 +327958 Pitpnm3 MGI:MGI:2685726|Ensembl:ENSMUSG00000040543|Vega:OTTMUSG00000006099 +327959 Xaf1 MGI:MGI:3772572|Ensembl:ENSMUSG00000040483|Vega:OTTMUSG00000006106 +327963 Zfp616 MGI:MGI:3650906|Ensembl:ENSMUSG00000069476 +327978 Slfn5 MGI:MGI:1329004|Ensembl:ENSMUSG00000054404|Vega:OTTMUSG00000000921 +327984 E130101M22 - +327986 Gm11444 MGI:MGI:3651161 +327987 Med13 MGI:MGI:3029632|Ensembl:ENSMUSG00000034297|Vega:OTTMUSG00000001199 +327988 Gm9975 MGI:MGI:3642180 +327992 Hsf5 MGI:MGI:2685585|Ensembl:ENSMUSG00000070345|Vega:OTTMUSG00000001291 +328019 Spata32 MGI:MGI:3045340|Ensembl:ENSMUSG00000044787|Vega:OTTMUSG00000003035 +328035 Fads6 MGI:MGI:3039592|Ensembl:ENSMUSG00000044788|Vega:OTTMUSG00000003748 +328049 C130090J04 - +328059 Slc7a15 MGI:MGI:3045351|Ensembl:ENSMUSG00000020600|Vega:OTTMUSG00000027490 +328061 Gm38407 MGI:MGI:5621292|Ensembl:ENSMUSG00000112792 +328066 LOC328066 - +328069 Gm4166 MGI:MGI:3782342 +328075 C630031E19Rik MGI:MGI:5439405|Ensembl:ENSMUSG00000112663 +328087 D930001B02 - +328092 Dtd2 MGI:MGI:1923485|Ensembl:ENSMUSG00000020956|Vega:OTTMUSG00000027701 +328099 Prps1l3 MGI:MGI:3779453|Ensembl:ENSMUSG00000079104|Vega:OTTMUSG00000032627 +328108 Togaram1 MGI:MGI:2684313|Ensembl:ENSMUSG00000035614 +328110 Prpf39 MGI:MGI:104602|Ensembl:ENSMUSG00000035597|Vega:OTTMUSG00000028931 +328113 A230055C15 - +328133 Slc39a9 MGI:MGI:1914820|Ensembl:ENSMUSG00000048833 +328136 Gm805 MGI:MGI:2685651|Ensembl:ENSMUSG00000097543 +328156 C230037L09 - +328162 Trmt61a MGI:MGI:2443487|Ensembl:ENSMUSG00000060950 +328166 Gm26583 MGI:MGI:5477077 +328186 Gm10336 MGI:MGI:3642355 +328190 A530046M15Rik MGI:MGI:5439406|Ensembl:ENSMUSG00000113338 +328191 B230303A05Rik MGI:MGI:3646895 +328192 9530076L18 - +328231 Gm5082 MGI:MGI:3644232|Ensembl:ENSMUSG00000054258 +328232 Gfod1 MGI:MGI:2145304|Ensembl:ENSMUSG00000051335 +328233 C230040D14 - +328234 Rnf182 MGI:MGI:3045355|Ensembl:ENSMUSG00000044164|Vega:OTTMUSG00000029082 +328235 Gm5083 MGI:MGI:3779454|Ensembl:ENSMUSG00000089815 +328243 E230012P03 - +328245 E030007A22Rik MGI:MGI:4437722 +328250 Nutm2 MGI:MGI:2685652|Ensembl:ENSMUSG00000071909|Vega:OTTMUSG00000027743 +328258 Slc25a48 MGI:MGI:2145373|Ensembl:ENSMUSG00000021509|Vega:OTTMUSG00000027753 +328263 A530065N20Rik MGI:MGI:5439407 +328265 A530001N23Rik MGI:MGI:3045361 +328274 Zfp459 MGI:MGI:3040701|Ensembl:ENSMUSG00000055560|Vega:OTTMUSG00000042791 +328277 Gm5085 - +328287 Gm20554 MGI:MGI:5295661 +328309 Gm9776 MGI:MGI:3641792|Ensembl:ENSMUSG00000042857 +328314 Gm5086 MGI:MGI:3644417|Ensembl:ENSMUSG00000110235 +328320 Gm807 MGI:MGI:2685653|Ensembl:ENSMUSG00000097848 +328324 5930438M14Rik MGI:MGI:5439408 +328329 Mast4 MGI:MGI:1918885|Ensembl:ENSMUSG00000034751|Vega:OTTMUSG00000035371 +328330 D130037M23Rik MGI:MGI:3027005 +328334 D230016O17 - +328353 D030051J21Rik MGI:MGI:2685588 +328354 Gm5087 MGI:MGI:3643653|Ensembl:ENSMUSG00000051729 +328362 Gm38408 MGI:MGI:5621293 +328365 Zmiz1 MGI:MGI:3040693|Ensembl:ENSMUSG00000007817|Vega:OTTMUSG00000034637 +328366 C130057D09Rik MGI:MGI:3028078 +328370 Rft1 MGI:MGI:3607791|Ensembl:ENSMUSG00000052395|Vega:OTTMUSG00000025088 +328373 A530028O18 - +328381 Sh2d4b MGI:MGI:1925182|Ensembl:ENSMUSG00000037833|Vega:OTTMUSG00000022977 +328385 D330046F09Rik MGI:MGI:2685654 +328388 Gm10101 MGI:MGI:3641713 +328399 A930018M24Rik MGI:MGI:2686053 +328401 Rnase9 MGI:MGI:3057273|Ensembl:ENSMUSG00000052382 +328417 Parp4 MGI:MGI:2685589|Ensembl:ENSMUSG00000054509|Vega:OTTMUSG00000034672 +328424 Kcnrg MGI:MGI:2685591|Ensembl:ENSMUSG00000046168 +328429 C230072K23 - +328436 Gm38409 MGI:MGI:5621294 +328440 Npm2 MGI:MGI:1890811|Ensembl:ENSMUSG00000047911 +328443 E130202H07Rik MGI:MGI:2685655 +328448 LOC328448 - +328451 Gm5088 MGI:MGI:3644528 +328456 6720482D04 - +328479 Gm5089 MGI:MGI:3644731|Ensembl:ENSMUSG00000064052 +328482 Trav9d-2 MGI:MGI:3704129|IMGT/GENE-DB:TRAV9D-2 +328483 Trav6-3 MGI:MGI:3649610|IMGT/GENE-DB:TRAV6-3 +328489 A630020A06 Ensembl:ENSMUSG00000097662 +328505 Skint7 MGI:MGI:3041190|Ensembl:ENSMUSG00000049214|Vega:OTTMUSG00000008506 +328516 Gm20555 MGI:MGI:5295662 +328530 D030063E12 - +328531 9330182O14Rik MGI:MGI:3045378|Ensembl:ENSMUSG00000094112 +328545 B830032F12 - +328561 Apol10b MGI:MGI:3043522|Ensembl:ENSMUSG00000050014|Vega:OTTMUSG00000035236 +328563 Apol11b MGI:MGI:3036248|Ensembl:ENSMUSG00000091694|Vega:OTTMUSG00000042502 +328572 Ep300 MGI:MGI:1276116|Ensembl:ENSMUSG00000055024|Vega:OTTMUSG00000048223 +328573 4930407I10Rik MGI:MGI:2685593|Ensembl:ENSMUSG00000075524 +328576 Gm20556 MGI:MGI:5295663 +328577 7530416G11Rik MGI:MGI:3036279|Ensembl:ENSMUSG00000096607 +328579 B230214G05Rik MGI:MGI:5439409 +328580 Tubgcp6 MGI:MGI:2146071|Ensembl:ENSMUSG00000051786|Vega:OTTMUSG00000021006 +328594 D630010B17Rik MGI:MGI:2685657 +328606 4731420N21 - +328633 4930515I15 - +328643 Vwa5b2 MGI:MGI:2681859|Ensembl:ENSMUSG00000046613|Vega:OTTMUSG00000026177 +328646 Gm16863 MGI:MGI:4439787|Ensembl:ENSMUSG00000096918 +328657 Gm1968 MGI:MGI:3584525 +328660 Bex6 MGI:MGI:3588247|Ensembl:ENSMUSG00000075269|Vega:OTTMUSG00000025822 +328695 Gm813 MGI:MGI:2685659|Ensembl:ENSMUSG00000075002 +328699 Gabrr3 MGI:MGI:3588203|Ensembl:ENSMUSG00000074991 +328734 Pisd-ps2 MGI:MGI:3612472 +328747 Gm5091 MGI:MGI:3779456|Ensembl:ENSMUSG00000097624 +328748 A930024N18Rik MGI:MGI:4360907 +328759 Vmn2r95 MGI:MGI:3761354|Ensembl:ENSMUSG00000091631|Vega:OTTMUSG00000039019 +328766 Gm5092 MGI:MGI:3779457|Ensembl:ENSMUSG00000102080 +328778 Rab26 MGI:MGI:2443284|Ensembl:ENSMUSG00000079657|Vega:OTTMUSG00000041995 +328779 Hs3st6 MGI:MGI:3580487|Ensembl:ENSMUSG00000039628 +328780 Prss34 MGI:MGI:2681414|Ensembl:ENSMUSG00000056399 +328783 Mslnl MGI:MGI:3607710|Ensembl:ENSMUSG00000041062 +328788 Clpsl2 MGI:MGI:2685595|Ensembl:ENSMUSG00000024224|Vega:OTTMUSG00000024248 +328789 Lhfpl5 MGI:MGI:1915382|Ensembl:ENSMUSG00000062252|Vega:OTTMUSG00000024253 +328795 Ubash3a MGI:MGI:1926074|Ensembl:ENSMUSG00000042345|Vega:OTTMUSG00000033209 +328801 Zfp414 MGI:MGI:1915641|Ensembl:ENSMUSG00000073423|Vega:OTTMUSG00000036514 +328825 Gm5093 MGI:MGI:3644404|Ensembl:ENSMUSG00000091742 +328829 9830107B12Rik MGI:MGI:3608415|Ensembl:ENSMUSG00000073386 +328830 A530064D06Rik MGI:MGI:2443476|Ensembl:ENSMUSG00000043939 +328833 Treml2 MGI:MGI:2147038|Ensembl:ENSMUSG00000071068 +328837 C330011F03Rik MGI:MGI:5439410 +328839 Gm5094 MGI:MGI:3647348 +328845 Acsbg2 MGI:MGI:3587728|Ensembl:ENSMUSG00000024207|Vega:OTTMUSG00000031270 +328855 E330032C10Rik MGI:MGI:4437727 +328861 D430006K04 - +328872 D230038C21 - +328906 Gm15328 MGI:MGI:3705182|Ensembl:ENSMUSG00000086095 +328918 Zscan30 MGI:MGI:2685600|Ensembl:ENSMUSG00000024274 +328919 Gm38410 MGI:MGI:5621295 +328943 6030438J01 - +328945 B930099G20 - +328949 Mcc MGI:MGI:96930|Ensembl:ENSMUSG00000071856|Vega:OTTMUSG00000055565 +328953 Gm5095 MGI:MGI:3779458 +328957 9330117O12Rik MGI:MGI:5439411 +328963 G630071F17Rik MGI:MGI:5439412 +328967 Arhgef37 MGI:MGI:3045339|Ensembl:ENSMUSG00000045094 +328968 Carmn MGI:MGI:4439832 +328971 Spink10 MGI:MGI:3584533|Ensembl:ENSMUSG00000044176|Vega:OTTMUSG00000033398 +328977 Zfp532 MGI:MGI:3036282|Ensembl:ENSMUSG00000042439|Vega:OTTMUSG00000044410 +328986 A430085C19 - +329002 Zfp236 MGI:MGI:1926950|Ensembl:ENSMUSG00000041258|Vega:OTTMUSG00000044389 +329003 Zfp516 MGI:MGI:2443957|Ensembl:ENSMUSG00000058881 +329008 Gm5096 MGI:MGI:3643681 +329015 Atg2a MGI:MGI:1916291|Ensembl:ENSMUSG00000024773|Vega:OTTMUSG00000018614 +329047 Gm815 MGI:MGI:2685661|Ensembl:ENSMUSG00000074913 +329055 Lipo1 MGI:MGI:3647308|Ensembl:ENSMUSG00000079342 +329056 A830019P07Rik MGI:MGI:3028035|Ensembl:ENSMUSG00000094707 +329064 Pkd2l1 MGI:MGI:1352448|Ensembl:ENSMUSG00000037578|Vega:OTTMUSG00000033257 +329065 Scd4 MGI:MGI:2670997|Ensembl:ENSMUSG00000050195|Vega:OTTMUSG00000028380 +329068 A330044H09 - +329078 Emx2os MGI:MGI:3052329|Ensembl:ENSMUSG00000087095 +329093 Cpa6 MGI:MGI:3045348|Ensembl:ENSMUSG00000042501|Vega:OTTMUSG00000024232 +329096 Gm17644 MGI:MGI:4937278|Ensembl:ENSMUSG00000097171 +329101 D030040B21Rik MGI:MGI:4437728|Ensembl:ENSMUSG00000097744 +329123 Gm5099 MGI:MGI:3644917|Ensembl:ENSMUSG00000102716 +329126 Gm5100 MGI:MGI:3644919 +329152 Hecw2 MGI:MGI:2685817|Ensembl:ENSMUSG00000042807|Vega:OTTMUSG00000029246 +329154 Ankrd44 MGI:MGI:3045243|Ensembl:ENSMUSG00000052331|Vega:OTTMUSG00000042322 +329159 9130227L01Rik MGI:MGI:2445084|Ensembl:ENSMUSG00000099950 +329160 9130024F11Rik MGI:MGI:1926150|Ensembl:ENSMUSG00000087022 +329165 Abi2 MGI:MGI:106913|Ensembl:ENSMUSG00000026782|Vega:OTTMUSG00000047318 +329178 Unc80 MGI:MGI:2652882|Ensembl:ENSMUSG00000055567|Vega:OTTMUSG00000026091 +329188 Gm816 MGI:MGI:2685662 +329207 Rbm44 MGI:MGI:2685663|Ensembl:ENSMUSG00000070732|Vega:OTTMUSG00000048485 +329217 Panct2 MGI:MGI:3643517 +329239 Gm29455 MGI:MGI:5580161 +329244 Il19 MGI:MGI:1890472|Ensembl:ENSMUSG00000016524|Vega:OTTMUSG00000049115 +329251 Ppp1r12b MGI:MGI:1916417|Ensembl:ENSMUSG00000073557|Vega:OTTMUSG00000021600 +329252 Lgr6 MGI:MGI:2441805|Ensembl:ENSMUSG00000042793|Vega:OTTMUSG00000026806 +329253 Gm15850 MGI:MGI:3801986|Ensembl:ENSMUSG00000086264 +329260 Dennd1b MGI:MGI:2447812|Ensembl:ENSMUSG00000056268|Vega:OTTMUSG00000033401 +329271 C230024C17Rik MGI:MGI:5439413|Ensembl:ENSMUSG00000100334 +329273 C130058N19 - +329274 Fam163a MGI:MGI:3618859|Ensembl:ENSMUSG00000015484|Vega:OTTMUSG00000050341 +329278 Tnn MGI:MGI:2665790|Ensembl:ENSMUSG00000026725|Vega:OTTMUSG00000025412 +329307 A430110L20Rik MGI:MGI:3036249|Ensembl:ENSMUSG00000054135 +329316 Gm37896 MGI:MGI:5611124|Ensembl:ENSMUSG00000103923 +329324 Syt14 MGI:MGI:2444490|Ensembl:ENSMUSG00000016200|Vega:OTTMUSG00000050853 +329358 Gm13387 MGI:MGI:3651242|Ensembl:ENSMUSG00000087028 +329360 Rnf224 MGI:MGI:2685603|Ensembl:ENSMUSG00000089953|Vega:OTTMUSG00000011888 +329366 Ccdc187 MGI:MGI:3045295|Ensembl:ENSMUSG00000048038|Vega:OTTMUSG00000012732 +329369 Snhg7os MGI:MGI:3045374 +329371 Dbhos MGI:MGI:3652314|Ensembl:ENSMUSG00000085008 +329372 D2Bwg1423e MGI:MGI:106557 +329375 Cfap77 MGI:MGI:2685669|Ensembl:ENSMUSG00000079502|Vega:OTTMUSG00000011819 +329384 Ptrh1 MGI:MGI:1913779|Ensembl:ENSMUSG00000053746|Vega:OTTMUSG00000012532 +329387 C230014O12Rik MGI:MGI:3045377|Ensembl:ENSMUSG00000087461 +329404 Gm13497 MGI:MGI:3650384|Ensembl:ENSMUSG00000086349 +329416 Nostrin MGI:MGI:3606242|Ensembl:ENSMUSG00000034738|Vega:OTTMUSG00000012971 +329421 Myo3b MGI:MGI:2448580|Ensembl:ENSMUSG00000042064|Vega:OTTMUSG00000013112 +329427 Chn1os3 MGI:MGI:3705094|Ensembl:ENSMUSG00000086544 +329430 A330043C09Rik MGI:MGI:2685671 +329436 Gm14461 MGI:MGI:3651589 +329460 Olfr1193 MGI:MGI:3031027|Ensembl:ENSMUSG00000060827|Vega:OTTMUSG00000013978 +329470 Accs MGI:MGI:1919717|Ensembl:ENSMUSG00000040272|Vega:OTTMUSG00000014985 +329478 C130078N14 - +329480 Wt1os MGI:MGI:2138884|Ensembl:ENSMUSG00000074987 +329482 Dcdc5 MGI:MGI:3045363 +329483 Gm14015 MGI:MGI:3649269|Ensembl:ENSMUSG00000087226 +329496 Gm13986 MGI:MGI:3651937|Ensembl:ENSMUSG00000087203 +329502 Pla2g4e MGI:MGI:1919144|Ensembl:ENSMUSG00000050211|Vega:OTTMUSG00000015277 +329504 Lcmt2 MGI:MGI:1353659|Ensembl:ENSMUSG00000074890|Vega:OTTMUSG00000015970 +329506 Ctdspl2 MGI:MGI:1196405|Ensembl:ENSMUSG00000033411|Vega:OTTMUSG00000015440 +329509 1810024B03Rik MGI:MGI:1925560|Ensembl:ENSMUSG00000044145|Vega:OTTMUSG00000016011 +329513 A730036I17Rik MGI:MGI:3041182|Ensembl:ENSMUSG00000056738 +329514 Il1bos MGI:MGI:3650458|Ensembl:ENSMUSG00000074805 +329540 Nol4l MGI:MGI:1918765|Ensembl:ENSMUSG00000061411|Vega:OTTMUSG00000016765 +329547 Bpi MGI:MGI:3045315|Ensembl:ENSMUSG00000052922|Vega:OTTMUSG00000015932 +329554 Gm826 MGI:MGI:2685672|Ensembl:ENSMUSG00000074623|Vega:OTTMUSG00000015995 +329557 Svs3b MGI:MGI:3583778|Ensembl:ENSMUSG00000050383|Vega:OTTMUSG00000016243 +329559 Zfp335 MGI:MGI:2682313|Ensembl:ENSMUSG00000039834|Vega:OTTMUSG00000001111 +329562 A530013C23Rik MGI:MGI:3041178|Ensembl:ENSMUSG00000006462 +329575 Gm14325 MGI:MGI:3702875|Ensembl:ENSMUSG00000095362|Vega:OTTMUSG00000016325 +329581 Birc7 MGI:MGI:2676458|Ensembl:ENSMUSG00000038840|Vega:OTTMUSG00000016404 +329584 Slc2a4rg-ps MGI:MGI:3651388|Ensembl:ENSMUSG00000085028 +329623 Gm11548 MGI:MGI:3650340|Ensembl:ENSMUSG00000085320 +329626 Fgf2os MGI:MGI:3649376 +329628 Fat4 MGI:MGI:3045256|Ensembl:ENSMUSG00000046743|Vega:OTTMUSG00000024693 +329633 Gm20557 MGI:MGI:5295664 +329636 Gm5103 MGI:MGI:3779459|Ensembl:ENSMUSG00000102544 +329639 Gm2447 MGI:MGI:3780614|Ensembl:ENSMUSG00000102785 +329641 Sertm1 MGI:MGI:3607715|Ensembl:ENSMUSG00000056306|Vega:OTTMUSG00000034733 +329642 D930017F01 - +329644 D930045L01 - +329650 Med12l MGI:MGI:2139916|Ensembl:ENSMUSG00000056476|Vega:OTTMUSG00000052449 +329655 LOC329655 - +329659 E130311K13Rik MGI:MGI:3607716|Ensembl:ENSMUSG00000048581|Vega:OTTMUSG00000034984 +329679 Fnip2 MGI:MGI:2683054|Ensembl:ENSMUSG00000061175|Vega:OTTMUSG00000030602 +329693 Fcrl5 MGI:MGI:3053558|Ensembl:ENSMUSG00000048031|Vega:OTTMUSG00000051867 +329696 A630076J08 - +329697 AI849053 MGI:MGI:2139818 +329702 Dcst2 MGI:MGI:2685606|Ensembl:ENSMUSG00000109293|Vega:OTTMUSG00000059281 +329706 Gm5104 MGI:MGI:3645549 +329711 Gm38411 MGI:MGI:5621296 +329716 BC107364 MGI:MGI:3618860|Ensembl:ENSMUSG00000046317|Vega:OTTMUSG00000053131 +329727 Dennd2c MGI:MGI:3036254|Ensembl:ENSMUSG00000007379|Vega:OTTMUSG00000037717 +329730 Gm38412 MGI:MGI:5621297|Ensembl:ENSMUSG00000104768 +329731 Fam19a3 MGI:MGI:3046463|Ensembl:ENSMUSG00000055865|Vega:OTTMUSG00000029328 +329735 4933431E20Rik MGI:MGI:3584041|Ensembl:ENSMUSG00000086968 +329738 Aknad1 MGI:MGI:3584453|Ensembl:ENSMUSG00000049565|Vega:OTTMUSG00000007252 +329739 Fam102b MGI:MGI:3036259|Ensembl:ENSMUSG00000040339|Vega:OTTMUSG00000007289 +329753 9830132P13Rik MGI:MGI:5439414|Ensembl:ENSMUSG00000104763 +329759 9330210C06 - +329763 Gm5105 MGI:MGI:3645344|Ensembl:ENSMUSG00000049349|Vega:OTTMUSG00000030596 +329765 D030063B19 - +329777 Pigk MGI:MGI:1913863|Ensembl:ENSMUSG00000039047|Vega:OTTMUSG00000031801 +329780 9330178D15Rik MGI:MGI:4437729|Ensembl:ENSMUSG00000104553 +329782 4930570G19Rik MGI:MGI:1923158|Ensembl:ENSMUSG00000085084 +329790 A630034I12Rik MGI:MGI:3041215 +329795 Tmem67 MGI:MGI:1923928|Ensembl:ENSMUSG00000049488|Vega:OTTMUSG00000004570 +329797 Gm11823 MGI:MGI:3651314|Ensembl:ENSMUSG00000086927 +329814 Lasc1 - +329824 Gm12384 MGI:MGI:3651222 +329828 AI464131 MGI:MGI:2140300|Ensembl:ENSMUSG00000046312|Vega:OTTMUSG00000006655 +329831 Fam166b MGI:MGI:2445194|Ensembl:ENSMUSG00000042788|Vega:OTTMUSG00000006822 +329839 Gm829 MGI:MGI:2685675 +329844 C630028M04Rik MGI:MGI:3045376|Ensembl:ENSMUSG00000085515 +329851 Gm12530 MGI:MGI:3651546|Ensembl:ENSMUSG00000085967 +329872 Frem1 MGI:MGI:2670972|Ensembl:ENSMUSG00000059049|Vega:OTTMUSG00000000404 +329876 Gm12680 MGI:MGI:3650846 +329877 Dennd4c MGI:MGI:1914769|Ensembl:ENSMUSG00000038024|Vega:OTTMUSG00000007709 +329892 Gm830 MGI:MGI:2685676 +329906 C030014L02 - +329908 Usp24 MGI:MGI:1919936|Ensembl:ENSMUSG00000028514|Vega:OTTMUSG00000008150 +329909 Tmem61 MGI:MGI:3041156 +329910 Acot11 MGI:MGI:1913736|Ensembl:ENSMUSG00000034853|Vega:OTTMUSG00000008201 +329917 4632401L01 - +329918 Skint9 MGI:MGI:3045341|Ensembl:ENSMUSG00000049972|Vega:OTTMUSG00000008551 +329919 Skint2 MGI:MGI:3649629|Ensembl:ENSMUSG00000034359|Vega:OTTMUSG00000008540 +329934 Foxo6 MGI:MGI:2676586|Ensembl:ENSMUSG00000052135|Vega:OTTMUSG00000008782 +329941 Col8a2 MGI:MGI:88464|Ensembl:ENSMUSG00000056174|Vega:OTTMUSG00000009356 +329942 Csmd2 MGI:MGI:2386401|Ensembl:ENSMUSG00000028804|Vega:OTTMUSG00000009459 +329950 Gm831 MGI:MGI:2685677 +329954 Catsper4 MGI:MGI:3043288|Ensembl:ENSMUSG00000048003|Vega:OTTMUSG00000020429 +329970 Gm13016 MGI:MGI:3650527 +329972 Spata21 MGI:MGI:3607787|Ensembl:ENSMUSG00000045004|Vega:OTTMUSG00000010148 +329973 C630004L07Rik MGI:MGI:3641643 +329977 Fhad1 MGI:MGI:1920323|Ensembl:ENSMUSG00000051435|Vega:OTTMUSG00000010111 +329984 Pramef25 MGI:MGI:3649968|Ensembl:ENSMUSG00000078511|Vega:OTTMUSG00000010441 +329986 BC080695 MGI:MGI:3525148|Ensembl:ENSMUSG00000070618|Vega:OTTMUSG00000010209 +329993 Gm438 MGI:MGI:2685284|Ensembl:ENSMUSG00000078504|Vega:OTTMUSG00000010746 +330004 Gm833 MGI:MGI:2685679 +330010 Ttll10 MGI:MGI:1921855|Ensembl:ENSMUSG00000029074|Vega:OTTMUSG00000010987 +330031 Gm5106 MGI:MGI:3643983 +330050 Fam185a MGI:MGI:2140983|Ensembl:ENSMUSG00000047221|Vega:OTTMUSG00000025660 +330052 A930003O13Rik MGI:MGI:3612704|Ensembl:ENSMUSG00000105076 +330053 4933427G23Rik MGI:MGI:3036235 +330059 A430017K17 - +330064 Slc5a6 MGI:MGI:2660847|Ensembl:ENSMUSG00000006641|Vega:OTTMUSG00000022376 +330070 Gm5107 MGI:MGI:3643506 +330086 Gm10440 MGI:MGI:3641803|Ensembl:ENSMUSG00000105912 +330096 Shisa3 MGI:MGI:3041225|Ensembl:ENSMUSG00000050010|Vega:OTTMUSG00000022536 +330097 Gm5108 MGI:MGI:3645064|Ensembl:ENSMUSG00000094719 +330107 E130218H05 - +330108 Gm20558 MGI:MGI:5295665 +330119 Adamts3 MGI:MGI:3045353|Ensembl:ENSMUSG00000043635|Vega:OTTMUSG00000055409 +330122 Cxcl3 MGI:MGI:3037818|Ensembl:ENSMUSG00000029379|Vega:OTTMUSG00000055506 +330132 A430057O09 - +330133 Gm38413 MGI:MGI:5621298|Ensembl:ENSMUSG00000105218 +330143 LOC330143 - +330146 4930458A03Rik MGI:MGI:2685681 +330149 Hfm1 MGI:MGI:3036246|Ensembl:ENSMUSG00000043410|Vega:OTTMUSG00000028149 +330150 A830011I04 - +330154 D830035I06 - +330164 C130026L21Rik MGI:MGI:3041189|Ensembl:ENSMUSG00000052848 +330166 Miat MGI:MGI:2444886|Ensembl:ENSMUSG00000097767 +330171 Kctd10 MGI:MGI:2141207|Ensembl:ENSMUSG00000001098|Vega:OTTMUSG00000014437 +330173 2610524H06Rik MGI:MGI:2447819|Ensembl:ENSMUSG00000092486|Vega:OTTMUSG00000037629 +330177 Taok3 MGI:MGI:3041177|Ensembl:ENSMUSG00000061288|Vega:OTTMUSG00000025729 +330183 Gm16063 MGI:MGI:3801955|Ensembl:ENSMUSG00000085708 +330188 Ccdc63 MGI:MGI:3607777|Ensembl:ENSMUSG00000043036|Vega:OTTMUSG00000024668 +330189 Tmem120b MGI:MGI:3603158|Ensembl:ENSMUSG00000054434|Vega:OTTMUSG00000030808 +330192 Vps37b MGI:MGI:1916724|Ensembl:ENSMUSG00000066278|Vega:OTTMUSG00000054785 +330216 Mblac1 MGI:MGI:2679717|Ensembl:ENSMUSG00000049285|Vega:OTTMUSG00000054667 +330217 Gal3st4 MGI:MGI:1916254|Ensembl:ENSMUSG00000075593|Vega:OTTMUSG00000022755 +330222 Sdk1 MGI:MGI:2444413|Ensembl:ENSMUSG00000039683|Vega:OTTMUSG00000029307 +330228 Spdye4b MGI:MGI:3612701|Ensembl:ENSMUSG00000029586|Vega:OTTMUSG00000031824 +330230 Zfp853 MGI:MGI:2685638|Ensembl:ENSMUSG00000093910|Vega:OTTMUSG00000061928 +330256 Gm20559 MGI:MGI:5295666 +330260 Pon2 MGI:MGI:106687|Ensembl:ENSMUSG00000032667|Vega:OTTMUSG00000023259 +330264 Gm5110 MGI:MGI:3644971 +330267 Thsd7a MGI:MGI:2685683|Ensembl:ENSMUSG00000032625|Vega:OTTMUSG00000030700 +330277 Fam71f1 MGI:MGI:3032524|Ensembl:ENSMUSG00000039742|Vega:OTTMUSG00000024002 +330283 Plxna4os2 MGI:MGI:3045237 +330286 D630045J12Rik MGI:MGI:2669829|Ensembl:ENSMUSG00000063455|Vega:OTTMUSG00000030718 +330301 Zfp786 MGI:MGI:3026883|Ensembl:ENSMUSG00000051499|Vega:OTTMUSG00000022112 +330305 Gm5111 MGI:MGI:3645688|Ensembl:ENSMUSG00000052730 +330319 Wipf3 MGI:MGI:3044681|Ensembl:ENSMUSG00000086040|Vega:OTTMUSG00000033222 +330323 Mindy4 MGI:MGI:3583959|Ensembl:ENSMUSG00000038022|Vega:OTTMUSG00000057885 +330324 6430584L05Rik MGI:MGI:5439415|Ensembl:ENSMUSG00000108228 +330350 9130221F21Rik MGI:MGI:4840488|Ensembl:ENSMUSG00000108356 +330351 BC019510 MGI:MGI:3040670 +330354 Gm20560 MGI:MGI:5295667 +330355 Dnah6 MGI:MGI:107744|Ensembl:ENSMUSG00000052861|Vega:OTTMUSG00000022156 +330361 Gcfc2 MGI:MGI:2141656|Ensembl:ENSMUSG00000035125|Vega:OTTMUSG00000023152 +330369 Fbxo41 MGI:MGI:1261912|Ensembl:ENSMUSG00000047013|Vega:OTTMUSG00000029064 +330379 Gm839 MGI:MGI:2685685 +330385 9530026P05Rik MGI:MGI:1924659|Ensembl:ENSMUSG00000097462 +330390 Gm765 MGI:MGI:2685611|Ensembl:ENSMUSG00000090667|Vega:OTTMUSG00000057616 +330401 Tmcc1 MGI:MGI:2442368|Ensembl:ENSMUSG00000030126|Vega:OTTMUSG00000036987 +330402 D030044L04Rik MGI:MGI:2685687 +330403 Gm9946 MGI:MGI:3643134 +330406 B4galnt3 MGI:MGI:3041155|Ensembl:ENSMUSG00000041372|Vega:OTTMUSG00000023370 +330409 Cecr2 MGI:MGI:1923799|Ensembl:ENSMUSG00000071226|Vega:OTTMUSG00000023741 +330414 Gm5112 MGI:MGI:3779460 +330427 9330102E08Rik MGI:MGI:3026973|Ensembl:ENSMUSG00000107879 +330428 Tmem52b MGI:MGI:2442838|Ensembl:ENSMUSG00000030160|Vega:OTTMUSG00000056469 +330433 9630009C16 - +330440 Sult6b2 MGI:MGI:2685612|Ensembl:ENSMUSG00000048473|Vega:OTTMUSG00000022208 +330450 Far2 MGI:MGI:2687035|Ensembl:ENSMUSG00000030303|Vega:OTTMUSG00000026047 +330460 Tmem150b MGI:MGI:2679718|Ensembl:ENSMUSG00000046456|Vega:OTTMUSG00000026275 +330463 Zfp78 MGI:MGI:107783|Ensembl:ENSMUSG00000055150|Vega:OTTMUSG00000060070 +330470 Bsph1 MGI:MGI:2685613|Ensembl:ENSMUSG00000074378|Vega:OTTMUSG00000056433 +330474 Zc3h4 MGI:MGI:2682314|Ensembl:ENSMUSG00000059273|Vega:OTTMUSG00000060585 +330479 D830036C21Rik MGI:MGI:2685688 +330483 Ceacam16 MGI:MGI:2685615|Ensembl:ENSMUSG00000014686|Vega:OTTMUSG00000037672 +330485 Tmem145 MGI:MGI:3607779|Ensembl:ENSMUSG00000043843|Vega:OTTMUSG00000031920 +330490 Nlrp9c MGI:MGI:3028627|Ensembl:ENSMUSG00000040614|Vega:OTTMUSG00000033294 +330491 Cyp2a21-ps MGI:MGI:3647278 +330496 Ifnl2 MGI:MGI:3647279|Ensembl:ENSMUSG00000059128|Vega:OTTMUSG00000059059 +330502 Zfp82 MGI:MGI:1890753|Ensembl:ENSMUSG00000098022|Vega:OTTMUSG00000044417 +330503 Gm5113 MGI:MGI:3644651|Ensembl:ENSMUSG00000066647 +330513 Gm5114 MGI:MGI:3647631|Ensembl:ENSMUSG00000053742|Vega:OTTMUSG00000049632 +330552 Gm9801 MGI:MGI:3647139 +330554 Fan1 MGI:MGI:3045266|Ensembl:ENSMUSG00000033458|Vega:OTTMUSG00000026085 +330577 Saxo2 MGI:MGI:1914618|Ensembl:ENSMUSG00000038570|Vega:OTTMUSG00000027323 +330578 A530021J07Rik MGI:MGI:3687211|Ensembl:ENSMUSG00000053528 +330581 Vmn2r69 MGI:MGI:3761311|Ensembl:ENSMUSG00000091006|Vega:OTTMUSG00000037834 +330593 5430421B17 - +330599 Gm16938 MGI:MGI:4439862 +330602 Gm5115 MGI:MGI:3643844 +330627 Trim66 MGI:MGI:2152406|Ensembl:ENSMUSG00000031026|Vega:OTTMUSG00000017446 +330635 3830612M24 - +330657 Prss53 MGI:MGI:2652890|Ensembl:ENSMUSG00000044139|Vega:OTTMUSG00000031114 +330660 Btbd16 MGI:MGI:3045247|Ensembl:ENSMUSG00000040298|Vega:OTTMUSG00000059645 +330662 Dock1 MGI:MGI:2429765|Ensembl:ENSMUSG00000058325|Vega:OTTMUSG00000060293 +330664 C230079O03Rik MGI:MGI:5439416|Ensembl:ENSMUSG00000109633 +330671 B4galnt4 MGI:MGI:2652891|Ensembl:ENSMUSG00000055629|Vega:OTTMUSG00000060385 +330677 Nctc1 MGI:MGI:1306816|Ensembl:ENSMUSG00000087090 +330689 Gm5116 MGI:MGI:3649164 +330695 Ctxn1 MGI:MGI:88566|Ensembl:ENSMUSG00000048644|Vega:OTTMUSG00000059346 +330721 Nek5 MGI:MGI:2142824|Ensembl:ENSMUSG00000037738|Vega:OTTMUSG00000060880 +330723 Htra4 MGI:MGI:3036260|Ensembl:ENSMUSG00000037406|Vega:OTTMUSG00000042143 +330731 Gm5117 MGI:MGI:3648041 +330734 B930018H19Rik MGI:MGI:5439417|Ensembl:ENSMUSG00000109819 +330737 5430403N17Rik MGI:MGI:5439418|Ensembl:ENSMUSG00000109761 +330738 Gm38414 MGI:MGI:5621299|Ensembl:ENSMUSG00000109704 +330767 1190028D05Rik MGI:MGI:3036227|Ensembl:ENSMUSG00000110013 +330776 Gm10283 MGI:MGI:3647628 +330780 E130110O22Rik MGI:MGI:3026945 +330788 Zfp866 MGI:MGI:3584369|Ensembl:ENSMUSG00000043090|Vega:OTTMUSG00000022394 +330790 Hapln4 MGI:MGI:2679531|Ensembl:ENSMUSG00000007594|Vega:OTTMUSG00000062214 +330796 Gm38415 MGI:MGI:5621300 +330804 E330022O07 - +330812 Rnf150 MGI:MGI:2443860|Ensembl:ENSMUSG00000047747|Vega:OTTMUSG00000061392 +330814 Adgrl1 MGI:MGI:1929461|Ensembl:ENSMUSG00000013033|Vega:OTTMUSG00000032839 +330817 Dhps MGI:MGI:2683592|Ensembl:ENSMUSG00000060038|Vega:OTTMUSG00000031492 +330819 Gm5118 MGI:MGI:3645880 +330820 4933402J07Rik MGI:MGI:3607717|Ensembl:ENSMUSG00000069971|Vega:OTTMUSG00000030586 +330830 Drc7 MGI:MGI:2685616|Ensembl:ENSMUSG00000031786|Vega:OTTMUSG00000061712 +330836 Slc7a6 MGI:MGI:2142598|Ensembl:ENSMUSG00000031904|Vega:OTTMUSG00000061944 +330837 6030452D12Rik MGI:MGI:3045356 +330850 Gm38416 MGI:MGI:5621301|Ensembl:ENSMUSG00000110151 +330863 Trim67 MGI:MGI:3045323|Ensembl:ENSMUSG00000036913|Vega:OTTMUSG00000022577 +330890 Piwil4 MGI:MGI:3041167|Ensembl:ENSMUSG00000036912|Vega:OTTMUSG00000024005 +330891 Gm5119 MGI:MGI:3645058 +330902 Gm16853 MGI:MGI:4439777|Ensembl:ENSMUSG00000097665 +330907 Gm5120 MGI:MGI:3646745 +330908 Opcml MGI:MGI:97397|Ensembl:ENSMUSG00000062257|Vega:OTTMUSG00000024277 +330914 Arhgap32 MGI:MGI:2450166|Ensembl:ENSMUSG00000041444|Vega:OTTMUSG00000036900 +330917 Gm27162 MGI:MGI:5521005 +330921 Pate2 MGI:MGI:2685692|Ensembl:ENSMUSG00000074452|Vega:OTTMUSG00000030731 +330938 Dixdc1 MGI:MGI:2679721|Ensembl:ENSMUSG00000032064|Vega:OTTMUSG00000031763 +330941 AI593442 MGI:MGI:2143099|Ensembl:ENSMUSG00000078307|Vega:OTTMUSG00000063098 +330951 Gm16130 MGI:MGI:3801718 +330953 Hcn4 MGI:MGI:1298209|Ensembl:ENSMUSG00000032338|Vega:OTTMUSG00000063286 +330956 Gm5122 MGI:MGI:3779461|Ensembl:ENSMUSG00000111290 +330958 A730043L09Rik MGI:MGI:5439419|Ensembl:ENSMUSG00000111232 +330959 Snapc5 MGI:MGI:1914282|Ensembl:ENSMUSG00000032398|Vega:OTTMUSG00000062591 +330962 Slc51b MGI:MGI:3582052|Ensembl:ENSMUSG00000053862|Vega:OTTMUSG00000062629 +330963 Ankdd1a MGI:MGI:2686319|Ensembl:ENSMUSG00000066510|Vega:OTTMUSG00000062637 +330998 Ankrd34c MGI:MGI:2685617|Ensembl:ENSMUSG00000047606|Vega:OTTMUSG00000046288 +331003 4933400C23Rik MGI:MGI:5439420|Ensembl:ENSMUSG00000101734 +331004 Slc9a9 MGI:MGI:2679732|Ensembl:ENSMUSG00000031129|Vega:OTTMUSG00000032832 +331006 C730026J16 - +331011 E330023G01Rik MGI:MGI:5439421|Ensembl:ENSMUSG00000102013 +331021 9630017O17 - +331026 Gmppb MGI:MGI:2660880|Ensembl:ENSMUSG00000070284|Vega:OTTMUSG00000016525 +331045 A530083I20Rik MGI:MGI:3040711 +331046 Tgm4 MGI:MGI:3027002|Ensembl:ENSMUSG00000025787|Vega:OTTMUSG00000023752 +331063 Gsdmc2 MGI:MGI:2146102|Ensembl:ENSMUSG00000056293|Vega:OTTMUSG00000045282 +331188 Zfp781 MGI:MGI:3696710|Ensembl:ENSMUSG00000096718 +331195 A430089I19Rik MGI:MGI:2683305|Ensembl:ENSMUSG00000094560|Vega:OTTMUSG00000055645 +331360 Zf12 - +331374 Dgkk MGI:MGI:3580254|Ensembl:ENSMUSG00000062393|Vega:OTTMUSG00000016656 +331380 Gm14510 MGI:MGI:3709641 +331391 Gm5123 MGI:MGI:3643621 +331392 Gm5124 MGI:MGI:3643622|Ensembl:ENSMUSG00000051537 +331401 Thoc2 MGI:MGI:2442413|Ensembl:ENSMUSG00000037475|Vega:OTTMUSG00000017445 +331416 Gm773 MGI:MGI:2685619|Ensembl:ENSMUSG00000073177|Vega:OTTMUSG00000017498 +331424 C230004F18Rik MGI:MGI:3041217|Ensembl:ENSMUSG00000071753 +331461 Il1rapl1 MGI:MGI:2687319|Ensembl:ENSMUSG00000052372|Vega:OTTMUSG00000016973 +331474 Rgag4 MGI:MGI:3045324|Ensembl:ENSMUSG00000049191|Vega:OTTMUSG00000018291 +331476 Gm5125 MGI:MGI:3645259 +331480 Gm5126 MGI:MGI:3649150 +331487 Uprt MGI:MGI:2685620|Ensembl:ENSMUSG00000073016|Vega:OTTMUSG00000018108 +331491 Fnd3c2 MGI:MGI:2685621|Ensembl:ENSMUSG00000073012|Vega:OTTMUSG00000018265 +331493 Gm5127 MGI:MGI:3648285|Ensembl:ENSMUSG00000073010|Vega:OTTMUSG00000018270 +331507 Gm1866 MGI:MGI:3037724 +331513 Gm9927 MGI:MGI:3642583 +331524 Xkrx MGI:MGI:3584011|Ensembl:ENSMUSG00000031258|Vega:OTTMUSG00000019158 +331528 LOC331528 - +331529 Gm5128 MGI:MGI:3647038|Ensembl:ENSMUSG00000094004|Vega:OTTMUSG00000018760 +331531 AV320801 MGI:MGI:3035227|Ensembl:ENSMUSG00000054994|Vega:OTTMUSG00000018770 +331532 Tceal5 MGI:MGI:3036236|Ensembl:ENSMUSG00000054034|Vega:OTTMUSG00000018780 +331535 Serpina7 MGI:MGI:3041197|Ensembl:ENSMUSG00000031271|Vega:OTTMUSG00000018699 +331537 Pih1h3b MGI:MGI:3607720|Ensembl:ENSMUSG00000042433|Vega:OTTMUSG00000018848 +331547 A230072E10Rik MGI:MGI:3603753|Ensembl:ENSMUSG00000084771 +331578 AW822252 MGI:MGI:2148030|Ensembl:ENSMUSG00000085998 +331623 Bend3 MGI:MGI:2677212|Ensembl:ENSMUSG00000038214|Vega:OTTMUSG00000063477 +332110 Mapk15 MGI:MGI:2652894|Ensembl:ENSMUSG00000063704|Vega:OTTMUSG00000034960 +332131 Krt78 MGI:MGI:1917529|Ensembl:ENSMUSG00000050463 +332175 Zdhhc23 MGI:MGI:2685625|Ensembl:ENSMUSG00000036304 +332221 Zscan10 MGI:MGI:3040700|Ensembl:ENSMUSG00000023902|Vega:OTTMUSG00000029797 +332309 Grxcr2 MGI:MGI:2685697|Ensembl:ENSMUSG00000073574 +332359 Tigd3 MGI:MGI:2681860|Ensembl:ENSMUSG00000044390 +332396 Kcnk18 MGI:MGI:2685627|Ensembl:ENSMUSG00000040901 +332397 Nanos1 MGI:MGI:2669254|Ensembl:ENSMUSG00000072437 +332427 Lyg2 MGI:MGI:2685622|Ensembl:ENSMUSG00000061584|Vega:OTTMUSG00000026561 +332578 Lcn10 MGI:MGI:1925000|Ensembl:ENSMUSG00000047356|Vega:OTTMUSG00000012510 +332579 Card9 MGI:MGI:2685628|Ensembl:ENSMUSG00000026928|Vega:OTTMUSG00000012770 +332713 Fndc11 MGI:MGI:3051572|Ensembl:ENSMUSG00000047841|Vega:OTTMUSG00000016564 +332923 Gm12794 MGI:MGI:3795847|Ensembl:ENSMUSG00000070890|Vega:OTTMUSG00000008450 +332934 Zmynd12 MGI:MGI:2140259|Ensembl:ENSMUSG00000070806|Vega:OTTMUSG00000009422 +332937 Tfap2e MGI:MGI:2679630|Ensembl:ENSMUSG00000042477|Vega:OTTMUSG00000009272 +332942 Gm853 MGI:MGI:2685699|Ensembl:ENSMUSG00000023120|Vega:OTTMUSG00000009562 +332993 Gm5129 MGI:MGI:3648499 +333048 Tmem211 MGI:MGI:2685700|Ensembl:ENSMUSG00000066964|Vega:OTTMUSG00000026851 +333050 Ksr2 MGI:MGI:3610315|Ensembl:ENSMUSG00000061578|Vega:OTTMUSG00000026829 +333088 Kcp MGI:MGI:2141640|Ensembl:ENSMUSG00000059022|Vega:OTTMUSG00000034248 +333182 Cox6b2 MGI:MGI:3044182|Ensembl:ENSMUSG00000051811|Vega:OTTMUSG00000043341 +333184 Gm5130 MGI:MGI:3643063 +333193 Proser3 MGI:MGI:2681861|Ensembl:ENSMUSG00000036864|Vega:OTTMUSG00000026205 +333307 Trim75 MGI:MGI:2685640|Ensembl:ENSMUSG00000071089|Vega:OTTMUSG00000061293 +333315 Frem3 MGI:MGI:2685641|Ensembl:ENSMUSG00000042353|Vega:OTTMUSG00000024568 +333329 Cngb1 MGI:MGI:2664102|Ensembl:ENSMUSG00000031789|Vega:OTTMUSG00000031171 +333331 Gm5131 MGI:MGI:3644589 +333424 A4gnt MGI:MGI:2143261|Ensembl:ENSMUSG00000037953|Vega:OTTMUSG00000048239 +333433 Gpd1l MGI:MGI:1289257|Ensembl:ENSMUSG00000050627|Vega:OTTMUSG00000033366 +333452 H2al1o MGI:MGI:3643069|Ensembl:ENSMUSG00000061065|Vega:OTTMUSG00000016892 +333467 B020031M17Rik MGI:MGI:3588226|Ensembl:ENSMUSG00000078537|Vega:OTTMUSG00000042964 +333473 Zfp36l3 MGI:MGI:3525151|Ensembl:ENSMUSG00000059334|Vega:OTTMUSG00000017388 +333563 Gm5133 MGI:MGI:3644182 +333564 Fndc3c1 MGI:MGI:2685630|Ensembl:ENSMUSG00000033737|Vega:OTTMUSG00000018273 +333588 Gm15104 MGI:MGI:3705199 +333605 Frmpd4 MGI:MGI:3042378|Ensembl:ENSMUSG00000049176|Vega:OTTMUSG00000019574 +333639 Mamld1 MGI:MGI:3045303|Ensembl:ENSMUSG00000059401|Vega:OTTMUSG00000017831 +333654 Ppp1r13l MGI:MGI:3525053|Ensembl:ENSMUSG00000040734|Vega:OTTMUSG00000029180 +333669 Gm5134 MGI:MGI:3646667|Ensembl:ENSMUSG00000033255|Vega:OTTMUSG00000031838 +333670 Gm867 MGI:MGI:2685713|Ensembl:ENSMUSG00000050157 +333715 H2-M10.2 MGI:MGI:1276525|Ensembl:ENSMUSG00000023083|Vega:OTTMUSG00000014948 +333789 N4bp2 MGI:MGI:2684414|Ensembl:ENSMUSG00000037795|Vega:OTTMUSG00000022204 +333830 Gm5135 MGI:MGI:3646830 +333883 Cd59b MGI:MGI:1888996|Ensembl:ENSMUSG00000068686|Vega:OTTMUSG00000014926 +333917 Gm14728 MGI:MGI:3705659 +337924 Cyp3a44 MGI:MGI:2449818|Ensembl:ENSMUSG00000054417|Vega:OTTMUSG00000025126 +338320 Mia2 MGI:MGI:2159614|Ensembl:ENSMUSG00000021000|Vega:OTTMUSG00000027665|Vega:OTTMUSG00000039748 +338337 Cog3 MGI:MGI:2450151|Ensembl:ENSMUSG00000034893 +338346 Gpr21 MGI:MGI:2441890|Ensembl:ENSMUSG00000053164|Vega:OTTMUSG00000012650 +338348 Ttc16 MGI:MGI:2443048|Ensembl:ENSMUSG00000039021|Vega:OTTMUSG00000012528 +338349 Cntln MGI:MGI:2443104|Ensembl:ENSMUSG00000038070|Vega:OTTMUSG00000006758 +338350 Acad12 MGI:MGI:2443320|Ensembl:ENSMUSG00000042647|Vega:OTTMUSG00000023497 +338351 Akap17b MGI:MGI:2443758|Ensembl:ENSMUSG00000059708|Vega:OTTMUSG00000017102 +338352 Nell1 MGI:MGI:2443902|Ensembl:ENSMUSG00000055409|Vega:OTTMUSG00000024734 +338354 Zfp780b MGI:MGI:2444764|Ensembl:ENSMUSG00000063047|Vega:OTTMUSG00000058622 +338355 Fkbp15 MGI:MGI:2444782|Ensembl:ENSMUSG00000066151|Vega:OTTMUSG00000000233 +338359 Supv3l1 MGI:MGI:2441711|Ensembl:ENSMUSG00000020079|Vega:OTTMUSG00000017268 +338360 B430212C06Rik MGI:MGI:2442134|Ensembl:ENSMUSG00000046415 +338362 Ust MGI:MGI:2442406|Ensembl:ENSMUSG00000047712 +338363 Tmem241 MGI:MGI:2442435|Ensembl:ENSMUSG00000049411|Vega:OTTMUSG00000060515 +338364 Trim65 MGI:MGI:2442815|Ensembl:ENSMUSG00000054517|Vega:OTTMUSG00000003756 +338365 Slc41a2 MGI:MGI:2442940|Ensembl:ENSMUSG00000034591|Vega:OTTMUSG00000024500 +338366 Mia3 MGI:MGI:2443183 +338367 Myo1d MGI:MGI:107728|Ensembl:ENSMUSG00000035441|Vega:OTTMUSG00000000216 +338368 Fam109b MGI:MGI:2443609|Ensembl:ENSMUSG00000049687|Vega:OTTMUSG00000034181 +338369 Tmem220 MGI:MGI:2443691|Ensembl:ENSMUSG00000050270|Vega:OTTMUSG00000005916 +338370 Nalcn MGI:MGI:2444306|Ensembl:ENSMUSG00000000197 +338371 Endov MGI:MGI:2444688|Ensembl:ENSMUSG00000039850|Vega:OTTMUSG00000003953 +338372 Map3k9 MGI:MGI:2449952|Ensembl:ENSMUSG00000042724 +338374 Ifnl3 MGI:MGI:2450574|Ensembl:ENSMUSG00000060747|Vega:OTTMUSG00000059060 +338375 Atp6v1g3 MGI:MGI:2450548|Ensembl:ENSMUSG00000026394|Vega:OTTMUSG00000026869 +338403 Cndp1 MGI:MGI:2451097|Ensembl:ENSMUSG00000056162|Vega:OTTMUSG00000028200 +338417 Scgb1c1 MGI:MGI:2655401|Ensembl:ENSMUSG00000038801|Vega:OTTMUSG00000045651 +338438 Hymai MGI:MGI:2651552 +338467 Morc3 MGI:MGI:2136841|Ensembl:ENSMUSG00000039456|Vega:OTTMUSG00000056162 +338521 Fa2h MGI:MGI:2443327|Ensembl:ENSMUSG00000033579|Vega:OTTMUSG00000027478 +338523 Kdm7a MGI:MGI:2443388|Ensembl:ENSMUSG00000042599|Vega:OTTMUSG00000022808 +338535 E030013I19Rik MGI:MGI:2443735|Ensembl:ENSMUSG00000086843 +347708 Dppa1 MGI:MGI:2157522|Ensembl:ENSMUSG00000064010|Vega:OTTMUSG00000005495 +347710 Pramel4 MGI:MGI:2156377|Ensembl:ENSMUSG00000073724|Vega:OTTMUSG00000010440 +347711 Pramel6 MGI:MGI:2156390|Ensembl:ENSMUSG00000025838|Vega:OTTMUSG00000013783 +347712 Pramel7 MGI:MGI:2156391|Ensembl:ENSMUSG00000025839|Vega:OTTMUSG00000013774 +347722 Agap1 MGI:MGI:2653690|Ensembl:ENSMUSG00000055013|Vega:OTTMUSG00000048341 +347723 Klra25 MGI:MGI:2653790 +347724 Klra17b MGI:MGI:2653800 +347726 Klra26 MGI:MGI:2653805 +347727 Klra28 MGI:MGI:2653811 +347740 2900097C17Rik MGI:MGI:1914767|Ensembl:ENSMUSG00000102869 +352945 BC005685 MGI:MGI:2655157 +352968 D830050J10Rik MGI:MGI:2444203 +353025 Caps2 MGI:MGI:2441980|Ensembl:ENSMUSG00000035694|Vega:OTTMUSG00000023544 +353047 Plekhm1 MGI:MGI:2443207|Ensembl:ENSMUSG00000034247|Vega:OTTMUSG00000002841 +353109 Scgb2b23-ps MGI:MGI:2655747|Ensembl:ENSMUSG00000083896 +353123 A830036E02Rik MGI:MGI:3686876 +353130 Prss33 MGI:MGI:2661234|Ensembl:ENSMUSG00000049620|Vega:OTTMUSG00000035218 +353148 Tas2r139 MGI:MGI:2681308|Ensembl:ENSMUSG00000047102|Vega:OTTMUSG00000057541 +353155 Gjd3 MGI:MGI:2384150|Ensembl:ENSMUSG00000047197|Vega:OTTMUSG00000006451 +353156 Egfl7 MGI:MGI:2449923|Ensembl:ENSMUSG00000026921|Vega:OTTMUSG00000011579 +353165 Tas2r136 MGI:MGI:2681304|Ensembl:ENSMUSG00000053217|Vega:OTTMUSG00000057025 +353166 Tas2r117 MGI:MGI:2681242|Ensembl:ENSMUSG00000058349|Vega:OTTMUSG00000056958 +353167 Tas2r123 MGI:MGI:2681264|Ensembl:ENSMUSG00000057381|Vega:OTTMUSG00000056961 +353169 Slc2a12 MGI:MGI:3052471|Ensembl:ENSMUSG00000037490|Vega:OTTMUSG00000028052 +353170 Txlng MGI:MGI:3590652|Ensembl:ENSMUSG00000038344|Vega:OTTMUSG00000019481 +353172 Gars MGI:MGI:2449057|Ensembl:ENSMUSG00000029777|Vega:OTTMUSG00000057767 +353187 Nr1d2 MGI:MGI:2449205|Ensembl:ENSMUSG00000021775|Vega:OTTMUSG00000033210 +353188 Adam32 MGI:MGI:2653822|Ensembl:ENSMUSG00000037437|Vega:OTTMUSG00000030527 +353190 Edc3 MGI:MGI:2142951|Ensembl:ENSMUSG00000038957|Vega:OTTMUSG00000033365 +353204 Aldoart1 MGI:MGI:2447811|Ensembl:ENSMUSG00000059343|Vega:OTTMUSG00000000336 +353208 Zfp931 MGI:MGI:2441662|Ensembl:ENSMUSG00000078861|Vega:OTTMUSG00000016320 +353211 Prune2 MGI:MGI:1925004|Ensembl:ENSMUSG00000039126 +353234 Pcdha2 MGI:MGI:2681880|Ensembl:ENSMUSG00000104148|Vega:OTTMUSG00000050586 +353235 Pcdha8 MGI:MGI:2681879|Ensembl:ENSMUSG00000103800|Vega:OTTMUSG00000050620 +353236 Pcdhac1 MGI:MGI:1891442|Ensembl:ENSMUSG00000103255|Vega:OTTMUSG00000050643 +353237 Pcdhac2 MGI:MGI:1891443|Ensembl:ENSMUSG00000102697|Vega:OTTMUSG00000050647 +353242 Mrpl21 MGI:MGI:2660674|Ensembl:ENSMUSG00000024829|Vega:OTTMUSG00000028246 +353258 Ltv1 MGI:MGI:2447810|Ensembl:ENSMUSG00000019814 +353282 Sfmbt2 MGI:MGI:2447794|Ensembl:ENSMUSG00000061186|Vega:OTTMUSG00000011189 +353283 Eras MGI:MGI:2665023|Ensembl:ENSMUSG00000031160|Vega:OTTMUSG00000018012 +353287 Clec18a MGI:MGI:2672935|Ensembl:ENSMUSG00000033633|Vega:OTTMUSG00000047805 +353310 Zfp703 MGI:MGI:2662729|Ensembl:ENSMUSG00000085795|Vega:OTTMUSG00000060973 +353320 Defb37 MGI:MGI:2672966|Ensembl:ENSMUSG00000053695|Vega:OTTMUSG00000020771 +353321 D13Jde1 MGI:MGI:2151713 +353325 Tas2r115 MGI:MGI:2681223|Ensembl:ENSMUSG00000071149|Vega:OTTMUSG00000056953 +353326 Rtl1 MGI:MGI:2656842|Ensembl:ENSMUSG00000085925 +353327 Mkrn1-ps1 MGI:MGI:2663191 +353328 Muc6 MGI:MGI:2663233|Ensembl:ENSMUSG00000048191|Vega:OTTMUSG00000047513 +353342 Peg13 MGI:MGI:2663476|Ensembl:ENSMUSG00000106847 +353344 Opn5 MGI:MGI:2662912|Ensembl:ENSMUSG00000043972 +353346 Gpr141 MGI:MGI:2672983|Ensembl:ENSMUSG00000053101 +353371 Oxct2b MGI:MGI:2664115|Ensembl:ENSMUSG00000076438|Vega:OTTMUSG00000008932 +353373 Rnu11 MGI:MGI:2148804 +353374 Snord61 MGI:MGI:2148805|Ensembl:ENSMUSG00000065110 +353499 Tmc4 MGI:MGI:2669035|Ensembl:ENSMUSG00000019734|Vega:OTTMUSG00000027890 +353502 Hcfc1r1 MGI:MGI:2663619|Ensembl:ENSMUSG00000023904|Vega:OTTMUSG00000042428 +353504 Dio3os MGI:MGI:2664395|Ensembl:ENSMUSG00000113581 +359846 DXMgc78 MGI:MGI:1350945 +359847 DXMgc77 MGI:MGI:1350960 +359848 DXMgc91 MGI:MGI:1859295 +359849 DXMgc96 MGI:MGI:1859300 +359850 DXMgc1 MGI:MGI:1099451 +359851 DXMgc3 MGI:MGI:1099453 +359852 DXMgc2 MGI:MGI:1099454 +359853 DXMgc5 MGI:MGI:1099458 +359854 DXMgc4 MGI:MGI:1099459 +359855 DXMgc9 MGI:MGI:1099449 +359856 DXMgc8 MGI:MGI:1099450 +359857 DXMgc7 MGI:MGI:1099456 +359858 DXMgc82 MGI:MGI:1350962 +359859 DXMgc44 MGI:MGI:1350964 +359860 DXMgc45 MGI:MGI:1350968 +359861 DXMgc89 MGI:MGI:1350972 +359862 DXMgc43 MGI:MGI:1350977 +359863 DXMgc80 MGI:MGI:1350978 +359864 DXMgc81 MGI:MGI:1350980 +359865 DXMgc42 MGI:MGI:1350983 +359866 DXMgc79 MGI:MGI:1350997 +359867 DXMgc38 MGI:MGI:1099415 +359868 DXMgc19 MGI:MGI:1099416 +359869 DXMgc18 MGI:MGI:1099417 +359870 DXMgc35 MGI:MGI:1099418 +359871 DXMgc22 MGI:MGI:1099420 +359872 DXMgc23 MGI:MGI:1099421 +359873 DXMgc20 MGI:MGI:1099422 +359874 DXMgc21 MGI:MGI:1099423 +359875 DXMgc26 MGI:MGI:1099424 +359876 DXMgc27 MGI:MGI:1099425 +359877 DXMgc24 MGI:MGI:1099426 +359878 DXMgc25 MGI:MGI:1099427 +359879 DXMgc40 MGI:MGI:1099428 +359880 DXMgc41 MGI:MGI:1099429 +359881 DXMgc36 MGI:MGI:1099430 +359882 DXMgc30 MGI:MGI:1099432 +359883 DXMgc31 MGI:MGI:1099433 +359884 DXMgc33 MGI:MGI:1099434 +359885 DXMgc32 MGI:MGI:1099435 +359886 DXMgc10 MGI:MGI:1099455 +359887 DXMgc28 MGI:MGI:1099466 +359888 DXMgc29 MGI:MGI:1099467 +359889 DXMgc37 MGI:MGI:1099468 +359890 DXMgc13 MGI:MGI:1099469 +359891 DXMgc12 MGI:MGI:1099470 +359892 DXMgc11 MGI:MGI:1099471 +359893 DXMgc17 MGI:MGI:1099473 +359894 DXMgc16 MGI:MGI:1099474 +359895 DXMgc15 MGI:MGI:1099475 +359896 DXMgc14 MGI:MGI:1099476 +359897 DXMgc39 MGI:MGI:1099477 +359898 DXMgc68 MGI:MGI:1350946 +359899 DXMgc69 MGI:MGI:1350947 +359900 DXMgc59 MGI:MGI:1350948 +359901 DXMgc58 MGI:MGI:1350949 +359902 DXMgc57 MGI:MGI:1350950 +359903 DXMgc56 MGI:MGI:1350951 +359904 DXMgc55 MGI:MGI:1350952 +359905 DXMgc54 MGI:MGI:1350953 +359906 DXMgc71 MGI:MGI:1350954 +359907 DXMgc70 MGI:MGI:1350955 +359908 DXMgc73 MGI:MGI:1350956 +359909 DXMgc50 MGI:MGI:1350957 +359910 DXMgc49 MGI:MGI:1350958 +359911 DXMgc74 MGI:MGI:1350959 +359912 DXMgc76 MGI:MGI:1350961 +359913 DXMgc85 MGI:MGI:1350965 +359914 DXMgc86 MGI:MGI:1350966 +359915 DXMgc87 MGI:MGI:1350967 +359916 DXMgc53 MGI:MGI:1350969 +359917 DXMgc52 MGI:MGI:1350970 +359918 DXMgc51 MGI:MGI:1350971 +359919 DXMgc72 MGI:MGI:1350973 +359920 DXMgc75 MGI:MGI:1350974 +359921 DXMgc84 MGI:MGI:1350982 +359922 DXMgc88 MGI:MGI:1350984 +359923 DXMgc48 MGI:MGI:1350988 +359924 DXMgc66 MGI:MGI:1350989 +359925 DXMgc67 MGI:MGI:1350990 +359926 DXMgc64 MGI:MGI:1350991 +359927 DXMgc65 MGI:MGI:1350992 +359928 DXMgc62 MGI:MGI:1350993 +359929 DXMgc63 MGI:MGI:1350994 +359930 DXMgc60 MGI:MGI:1350995 +359931 DXMgc61 MGI:MGI:1350996 +359932 DXMgc46 MGI:MGI:1350976 +359933 DXMgc90 MGI:MGI:1350987 +359960 DXMgc97 MGI:MGI:2667386 +359961 DXMgc98 MGI:MGI:2667387 +359962 DXMgc99 MGI:MGI:2667395 +359963 DXMgc100 MGI:MGI:2667397 +359964 DXMgc101 MGI:MGI:2667402 +359965 DXMgc102 MGI:MGI:2667404 +359966 DXMgc103 MGI:MGI:2667405 +359967 DXMgc104 MGI:MGI:2667406 +359968 DXMgc105 MGI:MGI:2667407 +359969 DXMgc106 MGI:MGI:2667408 +359970 DXMgc107 MGI:MGI:2667411 +359971 DXMgc108 MGI:MGI:2667448 +359972 DXMgc109 MGI:MGI:2667454 +359973 DXMgc110 MGI:MGI:2667457 +359974 DXMgc111 MGI:MGI:2667459 +359975 DXMgc112 MGI:MGI:2667461 +359976 DXMgc113 MGI:MGI:2667462 +359977 DXMgc114 MGI:MGI:2667466 +359978 DXMgc115 MGI:MGI:2667468 +359979 DXMgc116 MGI:MGI:2667469 +359980 DXMgc117 MGI:MGI:2667470 +359981 DXMgc118 MGI:MGI:2667471 +359982 DXMgc119 MGI:MGI:2667472 +359983 DXMgc120 MGI:MGI:2667473 +359984 DXMgc121 MGI:MGI:2667474 +359985 DXMgc122 MGI:MGI:2667475 +359986 DXMgc123 MGI:MGI:2667476 +359987 DXMgc124 MGI:MGI:2667477 +359988 DXMgc126 MGI:MGI:2667480 +359989 DXMgc127 MGI:MGI:2667481 +359990 DXMgc128 MGI:MGI:2667482 +359991 DXMgc129 MGI:MGI:2667483 +359992 DXMgc130 MGI:MGI:2667484 +359993 DXMgc131 MGI:MGI:2667486 +359994 DXMgc125 MGI:MGI:2667479 +360004 AF426179 MGI:MGI:2667662 +360013 Myo18a MGI:MGI:2667185|Ensembl:ENSMUSG00000000631|Vega:OTTMUSG00000000073 +360037 D17Jcs9 MGI:MGI:2668173 +360038 D17Jcs8 MGI:MGI:2668174 +360039 D17Jcs6 MGI:MGI:2668175 +360040 D17Jcs5 MGI:MGI:2668176 +360041 D17Jcs3 MGI:MGI:2668177 +360042 D17Jcs2 MGI:MGI:2668178 +360043 D17Jcs1 MGI:MGI:2668180 +360044 D17Brg3 MGI:MGI:2668088 +360045 D17Brg6 MGI:MGI:2668089 +360046 D17Jcs97 MGI:MGI:2668079 +360047 D17Jcs98 MGI:MGI:2668080 +360048 D17Jcs75 MGI:MGI:2668132 +360049 D17Jcs72 MGI:MGI:2668133 +360050 D17Jcs70 MGI:MGI:2668134 +360051 D17Jcs67 MGI:MGI:2668135 +360052 D17Jcs66 MGI:MGI:2668136 +360053 D17Jcs65 MGI:MGI:2668137 +360054 D17Jcs64 MGI:MGI:2668138 +360055 D17Jcs63 MGI:MGI:2668139 +360056 D17Jcs62 MGI:MGI:2668140 +360057 D17Jcs61 MGI:MGI:2668141 +360058 D17Jcs90 MGI:MGI:2668142 +360059 D17Jcs99 MGI:MGI:2668143 +360060 D17Jcs35 MGI:MGI:2668144 +360061 D17Jcs34 MGI:MGI:2668145 +360062 D17Jcs33 MGI:MGI:2668146 +360063 D17Jcs32 MGI:MGI:2668147 +360064 D17Jcs31 MGI:MGI:2668148 +360065 D17Jcs27 MGI:MGI:2668149 +360066 D17Jcs23 MGI:MGI:2668150 +360067 D17Jcs22 MGI:MGI:2668151 +360068 D17Jcs21 MGI:MGI:2668152 +360069 D17Jcs86 MGI:MGI:2668153 +360070 D17Jcs85 MGI:MGI:2668154 +360071 D17Jcs84 MGI:MGI:2668155 +360072 D17Jcs83 MGI:MGI:2668156 +360073 D17Jcs82 MGI:MGI:2668158 +360074 D17Jcs81 MGI:MGI:2668159 +360075 D17Jcs80 MGI:MGI:2668160 +360076 D17Jcs88 MGI:MGI:2668161 +360077 D17Jcs10 MGI:MGI:2668163 +360078 D17Jcs14 MGI:MGI:2668165 +360079 D17Jcs11 MGI:MGI:2668166 +360080 D17Jcs15 MGI:MGI:2668167 +360081 D17Jcs16 MGI:MGI:2668168 +360082 D17Jcs17 MGI:MGI:2668169 +360083 D17Jcs18 MGI:MGI:2668170 +360084 D17Jcs37 MGI:MGI:2668181 +360085 D17Jcs50 MGI:MGI:2668182 +360086 D17Jcs40 MGI:MGI:2668183 +360087 D17Jcs41 MGI:MGI:2668184 +360088 D17Jcs42 MGI:MGI:2668185 +360089 D17Jcs43 MGI:MGI:2668186 +360090 D17Jcs44 MGI:MGI:2668187 +360091 D17Jcs45 MGI:MGI:2668188 +360092 D17Jcs46 MGI:MGI:2668189 +360093 D17Jcs47 MGI:MGI:2668190 +360094 D17Jcs48 MGI:MGI:2668191 +360095 D17Jcs49 MGI:MGI:2668192 +360096 D17Jcs54 MGI:MGI:2668193 +360097 D17Jcs38 MGI:MGI:2668194 +360098 D17Jcs60 MGI:MGI:2668195 +360099 D17Jcs77 MGI:MGI:2668197 +360100 D17Brg10 MGI:MGI:2668090 +360101 D17Brg11 MGI:MGI:2668091 +360102 D17Brg18 MGI:MGI:2668092 +360103 D17Brg19 MGI:MGI:2668094 +360104 D17Brg22 MGI:MGI:2668095 +360105 D17Brg23 MGI:MGI:2668097 +360106 D17Brg29 MGI:MGI:2668101 +360107 D17Brg30 MGI:MGI:2668102 +360108 D17Jcs100 MGI:MGI:2668110 +360109 D17Jcs102 MGI:MGI:2668111 +360110 D17Jcs111 MGI:MGI:2668112 +360111 D17Jcs112 MGI:MGI:2668113 +360112 D17Jcs113 MGI:MGI:2668114 +360113 D17Jcs114 MGI:MGI:2668116 +360114 D17Jcs115 MGI:MGI:2668117 +360115 D17Jcs116 MGI:MGI:2668118 +360116 D17Jcs117 MGI:MGI:2668120 +360117 D17Jcs120 MGI:MGI:2668123 +360118 D17Jcs121 MGI:MGI:2668125 +360119 D17Jcs122 MGI:MGI:2668127 +360120 D17Jcs107 MGI:MGI:2668129 +360121 D17Jcs124 MGI:MGI:2668172 +360122 D17Brg119 MGI:MGI:2668099 +360123 D17Brg120 MGI:MGI:2668100 +360124 D17Brg198 MGI:MGI:2668103 +360125 D17Brg199 MGI:MGI:2668105 +360126 D17Brg125 MGI:MGI:2668106 +360127 D17Brg140 MGI:MGI:2668107 +360128 D17Brg152 MGI:MGI:2668108 +360129 D17Brg153 MGI:MGI:2668109 +360130 Gnb1-ps2 MGI:MGI:2668077 +360131 Gnb1-ps3 MGI:MGI:2668078 +360198 Hist1h3a MGI:MGI:2668828|Ensembl:ENSMUSG00000069265|Vega:OTTMUSG00000000578 +360211 Defb34 MGI:MGI:2672979|Ensembl:ENSMUSG00000052554|Vega:OTTMUSG00000020594 +360212 Defb38 MGI:MGI:2672972|Ensembl:ENSMUSG00000053790|Vega:OTTMUSG00000020768 +360213 Trim46 MGI:MGI:2673000|Ensembl:ENSMUSG00000042766|Vega:OTTMUSG00000021995 +360214 Defb39 MGI:MGI:2672974|Ensembl:ENSMUSG00000061847|Vega:OTTMUSG00000020770 +360216 Zranb1 MGI:MGI:106441|Ensembl:ENSMUSG00000030967|Vega:OTTMUSG00000025669 +360217 Defb40 MGI:MGI:2672976|Ensembl:ENSMUSG00000053678|Vega:OTTMUSG00000020772 +360220 Speer4d MGI:MGI:2668869|Ensembl:ENSMUSG00000070933|Vega:OTTMUSG00000026687 +360222 Raxos1 MGI:MGI:3583306 +360223 jams1 MGI:MGI:2149344 +368202 Prss48 MGI:MGI:2685865|Ensembl:ENSMUSG00000049013|Vega:OTTMUSG00000028790 +368203 Gm5136 MGI:MGI:3647286|Ensembl:ENSMUSG00000112039 +368204 Khdc1a MGI:MGI:2676610|Ensembl:ENSMUSG00000067750|Vega:OTTMUSG00000033754 +373852 4833422C13Rik MGI:MGI:3603826|Ensembl:ENSMUSG00000074782 +373864 Col27a1 MGI:MGI:2672118|Ensembl:ENSMUSG00000045672|Vega:OTTMUSG00000000244 +378425 Nlrp12 MGI:MGI:2676630|Ensembl:ENSMUSG00000078817|Vega:OTTMUSG00000057710 +378430 Nanos2 MGI:MGI:2676627|Ensembl:ENSMUSG00000051965|Vega:OTTMUSG00000058459 +378431 Txlnb MGI:MGI:2671945|Ensembl:ENSMUSG00000039891|Vega:OTTMUSG00000042108 +378435 Mafa MGI:MGI:2673307|Ensembl:ENSMUSG00000047591 +378460 Pram1 MGI:MGI:3576625|Ensembl:ENSMUSG00000032739|Vega:OTTMUSG00000036515 +378462 Morn2 MGI:MGI:2674071|Ensembl:ENSMUSG00000045257 +378466 Gm10033 MGI:MGI:3642803|Ensembl:ENSMUSG00000110444 +378472 Vaultrc5 MGI:MGI:2673990 +378473 Vaultrc-ps1 MGI:MGI:2673991 +378700 Bpifb3 MGI:MGI:2675077|Ensembl:ENSMUSG00000068008|Vega:OTTMUSG00000016852 +378702 Serf2 MGI:MGI:1337041|Ensembl:ENSMUSG00000074884|Vega:OTTMUSG00000015327 +378709 Musd1 MGI:MGI:2675046 +378710 Musd2 MGI:MGI:2675048 +378775 Pcsk2os2 MGI:MGI:3649365|Ensembl:ENSMUSG00000087115 +378776 Pcsk2os1 MGI:MGI:3605632|Ensembl:ENSMUSG00000086171 +378777 L1Md-A3 MGI:MGI:2675507 +378778 L1Md-A5 MGI:MGI:2675509 +378937 Lrrc24 MGI:MGI:3605040|Ensembl:ENSMUSG00000033707|Vega:OTTMUSG00000033518 +378954 3000002C10Rik MGI:MGI:3036226 +379043 Raet1e MGI:MGI:2675273|Ensembl:ENSMUSG00000053219|Vega:OTTMUSG00000042696 +380601 Fastkd5 MGI:MGI:2139469|Ensembl:ENSMUSG00000079043|Vega:OTTMUSG00000015493 +380608 Tagap1 MGI:MGI:1919786|Ensembl:ENSMUSG00000052031 +380612 Rapgef4os3 MGI:MGI:2442080 +380614 Intu MGI:MGI:2443752|Ensembl:ENSMUSG00000060798|Vega:OTTMUSG00000030600 +380629 Heca MGI:MGI:2685715|Ensembl:ENSMUSG00000039879 +380654 Cfap54 MGI:MGI:1922208|Ensembl:ENSMUSG00000020014|Vega:OTTMUSG00000036731 +380656 A230066D03Rik MGI:MGI:2686402 +380660 Acss3 MGI:MGI:2685720|Ensembl:ENSMUSG00000035948|Vega:OTTMUSG00000023051 +380664 Lemd3 MGI:MGI:3580376|Ensembl:ENSMUSG00000048661|Vega:OTTMUSG00000031195 +380669 Lin28b MGI:MGI:3584032|Ensembl:ENSMUSG00000063804|Vega:OTTMUSG00000063733 +380672 Gm1559 MGI:MGI:2686405 +380674 Rdh18-ps MGI:MGI:2687008 +380683 Sec14l3 MGI:MGI:3617848|Ensembl:ENSMUSG00000054986|Vega:OTTMUSG00000005046 +380684 Nefh MGI:MGI:97309|Ensembl:ENSMUSG00000020396|Vega:OTTMUSG00000005075 +380686 Cnrip1 MGI:MGI:1917505|Ensembl:ENSMUSG00000044629|Vega:OTTMUSG00000005191 +380687 Gm5138 MGI:MGI:3779464 +380694 Ccnjl MGI:MGI:2685723|Ensembl:ENSMUSG00000044707|Vega:OTTMUSG00000005455 +380696 Gm12194 MGI:MGI:3651099 +380698 Obscn MGI:MGI:2681862|Ensembl:ENSMUSG00000061462|Vega:OTTMUSG00000005776 +380701 Slc47a2 MGI:MGI:3588190|Ensembl:ENSMUSG00000069855|Vega:OTTMUSG00000005830 +380702 Shisa6 MGI:MGI:2685725|Ensembl:ENSMUSG00000053930|Vega:OTTMUSG00000005909 +380705 Tmem102 MGI:MGI:1921591|Ensembl:ENSMUSG00000089876|Vega:OTTMUSG00000005992 +380709 Spata22 MGI:MGI:2685728|Ensembl:ENSMUSG00000069825|Ensembl:ENSMUSG00000112920|Vega:OTTMUSG00000006129 +380711 Rap1gap2 MGI:MGI:3028623|Ensembl:ENSMUSG00000038807|Vega:OTTMUSG00000006182 +380712 Tlcd2 MGI:MGI:1917141|Ensembl:ENSMUSG00000038217|Vega:OTTMUSG00000006202 +380713 Scarf1 MGI:MGI:2449455|Ensembl:ENSMUSG00000038188|Vega:OTTMUSG00000006207 +380714 Rph3al MGI:MGI:1923492|Ensembl:ENSMUSG00000020847|Vega:OTTMUSG00000006223 +380718 Mks1 MGI:MGI:3584243|Ensembl:ENSMUSG00000034121|Vega:OTTMUSG00000001434 +380728 Kcnh4 MGI:MGI:2156184|Ensembl:ENSMUSG00000035355|Vega:OTTMUSG00000002129 +380730 Gm884 MGI:MGI:2685730|Ensembl:ENSMUSG00000034239|Vega:OTTMUSG00000003016 +380732 Milr1 MGI:MGI:2685731|Ensembl:ENSMUSG00000040528|Vega:OTTMUSG00000003586 +380739 Gm5139 MGI:MGI:3779465 +380752 Tssc1 MGI:MGI:1289332|Ensembl:ENSMUSG00000036613 +380753 Atxn7l1 MGI:MGI:3584458|Ensembl:ENSMUSG00000020564|Vega:OTTMUSG00000032964 +380755 Lsmem1 MGI:MGI:2685735|Ensembl:ENSMUSG00000071342 +380758 LOC380758 - +380765 D830013O20Rik MGI:MGI:2685737|Ensembl:ENSMUSG00000056359 +380768 Ccdc177 MGI:MGI:2686414|Ensembl:ENSMUSG00000062961 +380773 Slirp MGI:MGI:1916394|Ensembl:ENSMUSG00000021040|Vega:OTTMUSG00000033355 +380777 Naca-rs - +380780 Serpina11 MGI:MGI:2685741|Ensembl:ENSMUSG00000063232|Vega:OTTMUSG00000027621 +380785 Begain MGI:MGI:3044626|Ensembl:ENSMUSG00000040867|Vega:OTTMUSG00000047121 +380787 A230065H16Rik MGI:MGI:2685744|Ensembl:ENSMUSG00000087075|Vega:OTTMUSG00000059298 +380792 Ighe MGI:MGI:2685746|IMGT/GENE-DB:IGHE +380793 Ighg2a MGI:MGI:96443|IMGT/GENE-DB:IGHG2A +380794 Ighg MGI:MGI:2144967 +380795 Ighg3 MGI:MGI:2144790|IMGT/GENE-DB:IGHG3 +380797 Ighd MGI:MGI:96447|IMGT/GENE-DB:IGHD +380808 Ighv10-1 MGI:MGI:4439620|IMGT/GENE-DB:IGHV10-1 +380809 Ighv10-3 MGI:MGI:3648785|IMGT/GENE-DB:IGHV10-3 +380820 IghmAC38.205.12 - +380822 V165-D-J-C mu - +380823 Ighv1-64 MGI:MGI:4439789|IMGT/GENE-DB:IGHV1-64 +380824 Ighv1-66 MGI:MGI:4439825|IMGT/GENE-DB:IGHV1-66 +380836 Mrs2 MGI:MGI:2685748|Ensembl:ENSMUSG00000021339|Vega:OTTMUSG00000000614 +380839 Serpinb1c MGI:MGI:2445363|Ensembl:ENSMUSG00000079049|Vega:OTTMUSG00000000695 +380840 Lyrm4 MGI:MGI:2683538|Ensembl:ENSMUSG00000046573 +380842 Stmnd1 MGI:MGI:2686420|Ensembl:ENSMUSG00000063529 +380845 Gm904 MGI:MGI:2685750|Ensembl:ENSMUSG00000096641 +380850 Gm5141 MGI:MGI:3779466|Ensembl:ENSMUSG00000091183|Vega:OTTMUSG00000056315 +380855 Rsl1 MGI:MGI:3044162|Ensembl:ENSMUSG00000058900|Vega:OTTMUSG00000033721 +380863 Tmem171 MGI:MGI:2685751|Ensembl:ENSMUSG00000052485|Vega:OTTMUSG00000027705 +380878 AF067063 MGI:MGI:2687009|Ensembl:ENSMUSG00000094237|Vega:OTTMUSG00000050174 +380882 Gm906 MGI:MGI:2685752|Ensembl:ENSMUSG00000095300 +380889 LOC380889 - +380907 Gm5142 MGI:MGI:3647352|Ensembl:ENSMUSG00000053868 +380912 Zfp395 MGI:MGI:2682318|Ensembl:ENSMUSG00000034522 +380916 Lrch1 MGI:MGI:2443390|Ensembl:ENSMUSG00000068015 +380918 Siah3 MGI:MGI:2685758|Ensembl:ENSMUSG00000091722 +380920 Gm1587 MGI:MGI:2686433|Ensembl:ENSMUSG00000075512 +380921 Dgkh MGI:MGI:2444188|Ensembl:ENSMUSG00000034731 +380924 Olfm4 MGI:MGI:2685142|Ensembl:ENSMUSG00000022026 +380928 Lmo7 MGI:MGI:1353586|Ensembl:ENSMUSG00000033060|Vega:OTTMUSG00000034688 +380930 9330188P03Rik MGI:MGI:2686435 +380934 AA536875 MGI:MGI:2145569 +380959 Alg10b MGI:MGI:2146159|Ensembl:ENSMUSG00000075470 +380967 Tmem106c MGI:MGI:1196384|Ensembl:ENSMUSG00000052369 +380969 Nckap5l MGI:MGI:3609653|Ensembl:ENSMUSG00000023009|Vega:OTTMUSG00000034991 +380973 Fam186a MGI:MGI:2685766 +380975 Higd1c MGI:MGI:2685767|Ensembl:ENSMUSG00000093550|Vega:OTTMUSG00000042220 +380977 A330009N23Rik MGI:MGI:2443491|Ensembl:ENSMUSG00000097915 +380993 Zfat MGI:MGI:2681865|Ensembl:ENSMUSG00000022335|Vega:OTTMUSG00000033790 +380994 Gm20736 MGI:MGI:5434092|Ensembl:ENSMUSG00000093993|Vega:OTTMUSG00000045797 +380997 Cyp2d12 MGI:MGI:88604|Ensembl:ENSMUSG00000096852 +380998 Cyp2d36-ps MGI:MGI:3721931 +381002 Gm5144 MGI:MGI:3779468 +381022 Kmt2d MGI:MGI:2682319|Ensembl:ENSMUSG00000048154|Vega:OTTMUSG00000043160 +381033 Gm1600 MGI:MGI:2686446 +381038 Parl MGI:MGI:1277152|Ensembl:ENSMUSG00000033918|Vega:OTTMUSG00000025306 +381043 Gm933 MGI:MGI:2685779|Ensembl:ENSMUSG00000094430|Vega:OTTMUSG00000042808 +381045 Ccdc58 MGI:MGI:2146423|Ensembl:ENSMUSG00000075229 +381058 Unc93a MGI:MGI:1933250|Ensembl:ENSMUSG00000067049|Vega:OTTMUSG00000028082 +381059 Gm1604b MGI:MGI:2686450|Ensembl:ENSMUSG00000095720 +381062 Ermard MGI:MGI:1917317|Ensembl:ENSMUSG00000036552|Vega:OTTMUSG00000048322 +381065 Gm5145 MGI:MGI:3645482 +381066 Zfp948 MGI:MGI:3040683|Ensembl:ENSMUSG00000067931 +381067 Zfp229 MGI:MGI:2679295|Ensembl:ENSMUSG00000061544|Vega:OTTMUSG00000044387 +381070 Casp16-ps MGI:MGI:3646305 +381072 Abca17 MGI:MGI:3625331|Ensembl:ENSMUSG00000035435|Vega:OTTMUSG00000031262 +381073 Npw MGI:MGI:2685781|Ensembl:ENSMUSG00000071230|Vega:OTTMUSG00000047879 +381077 Ccdc78 MGI:MGI:2685784|Ensembl:ENSMUSG00000071202 +381083 Gm16194 MGI:MGI:3801773 +381085 Tbc1d22b MGI:MGI:2681867|Ensembl:ENSMUSG00000042203|Vega:OTTMUSG00000034448 +381091 H2-Eb2 MGI:MGI:95902|Ensembl:ENSMUSG00000067341|Vega:OTTMUSG00000020169 +381101 Dnph1 MGI:MGI:3039376|Ensembl:ENSMUSG00000040658 +381104 Prickle4 MGI:MGI:2685785|Ensembl:ENSMUSG00000079444|Ensembl:ENSMUSG00000096549|Vega:OTTMUSG00000018353|Vega:OTTMUSG00000042287 +381107 Tmem232 MGI:MGI:2685786|Ensembl:ENSMUSG00000045036 +381110 Rmdn2 MGI:MGI:2147043|Ensembl:ENSMUSG00000036368 +381112 Arhgef33 MGI:MGI:2685787|Ensembl:ENSMUSG00000054901 +381113 Cdkl4 MGI:MGI:3587025|Ensembl:ENSMUSG00000033966 +381122 Capn13 MGI:MGI:2685789|Ensembl:ENSMUSG00000043705 +381126 Garem1 MGI:MGI:2685790|Ensembl:ENSMUSG00000042680 +381142 Arl14epl MGI:MGI:2685795|Ensembl:ENSMUSG00000073568 +381144 4930541O19Rik MGI:MGI:2686459 +381148 Prob1 MGI:MGI:2686460|Ensembl:ENSMUSG00000073600|Vega:OTTMUSG00000048605 +381155 9630014M24Rik MGI:MGI:3588234 +381157 Greb1l MGI:MGI:3576497|Ensembl:ENSMUSG00000042942|Vega:OTTMUSG00000037156 +381174 A330084C13Rik MGI:MGI:2685802 +381175 Ccdc68 MGI:MGI:3612676|Ensembl:ENSMUSG00000038903|Vega:OTTMUSG00000028224 +381196 Gm960 MGI:MGI:2685806|Ensembl:ENSMUSG00000071691 +381199 Tmem151a MGI:MGI:2147713|Ensembl:ENSMUSG00000061451|Vega:OTTMUSG00000033051 +381201 Ap5b1 MGI:MGI:2685808|Ensembl:ENSMUSG00000049562 +381203 Slc22a20 MGI:MGI:2685809|Ensembl:ENSMUSG00000037451|Vega:OTTMUSG00000035357 +381204 Naaladl1 MGI:MGI:2685810|Ensembl:ENSMUSG00000054999|Vega:OTTMUSG00000035402 +381213 Ms4a12 MGI:MGI:2685812|Ensembl:ENSMUSG00000101031|Vega:OTTMUSG00000047056 +381217 Fam189a2 MGI:MGI:2685813|Ensembl:ENSMUSG00000071604 +381218 4430402I18Rik MGI:MGI:1918036|Ensembl:ENSMUSG00000064202|Vega:OTTMUSG00000033892 +381223 E030044B06Rik MGI:MGI:2686464 +381224 Gm340 MGI:MGI:2685186 +381229 Cfap58 MGI:MGI:2685815|Ensembl:ENSMUSG00000046585 +381232 Mirt1 MGI:MGI:1922001|Ensembl:ENSMUSG00000097636 +381236 Lipo3 MGI:MGI:2147592|Ensembl:ENSMUSG00000024766|Vega:OTTMUSG00000033059 +381246 Xkr9 MGI:MGI:2686466|Ensembl:ENSMUSG00000067813|Vega:OTTMUSG00000022137 +381258 Gm5147 MGI:MGI:3646018 +381259 Tmem237 MGI:MGI:2138365|Ensembl:ENSMUSG00000038079|Vega:OTTMUSG00000047221 +381260 Gm973 MGI:MGI:2685819|Ensembl:ENSMUSG00000047361|Vega:OTTMUSG00000047232 +381269 Mreg MGI:MGI:2151839|Ensembl:ENSMUSG00000039395|Vega:OTTMUSG00000049069 +381270 March4 MGI:MGI:2683550|Ensembl:ENSMUSG00000039372|Vega:OTTMUSG00000026658 +381272 A630095N17Rik MGI:MGI:2686470|Ensembl:ENSMUSG00000096094|Vega:OTTMUSG00000048574 +381280 Hjurp MGI:MGI:2685821|Ensembl:ENSMUSG00000044783|Vega:OTTMUSG00000020807 +381284 Crocc2 MGI:MGI:3045962|Ensembl:ENSMUSG00000084989|Vega:OTTMUSG00000033626 +381286 Serpinb3c MGI:MGI:1277952|Ensembl:ENSMUSG00000073601|Vega:OTTMUSG00000021005 +381287 A530032D15Rik MGI:MGI:3037746|Ensembl:ENSMUSG00000089844|Vega:OTTMUSG00000029176 +381290 Atp2b4 MGI:MGI:88111|Ensembl:ENSMUSG00000026463|Vega:OTTMUSG00000016442 +381291 Gm1627 MGI:MGI:2686473 +381293 Kif14 MGI:MGI:1098226|Ensembl:ENSMUSG00000041498|Vega:OTTMUSG00000046083 +381305 Rc3h1 MGI:MGI:2685397|Ensembl:ENSMUSG00000040423|Vega:OTTMUSG00000034799 +381306 BC055324 MGI:MGI:3590554|Ensembl:ENSMUSG00000041406|Vega:OTTMUSG00000034817 +381308 Ifi211 MGI:MGI:3041120|Ensembl:ENSMUSG00000026536|Vega:OTTMUSG00000050203 +381310 Stum MGI:MGI:2138735|Ensembl:ENSMUSG00000053963|Vega:OTTMUSG00000033911 +381314 Iars2 MGI:MGI:1919586|Ensembl:ENSMUSG00000026618|Vega:OTTMUSG00000021852 +381318 Nsl1 MGI:MGI:2685830|Ensembl:ENSMUSG00000062510|Vega:OTTMUSG00000029639 +381319 Batf3 MGI:MGI:1925491|Ensembl:ENSMUSG00000026630|Vega:OTTMUSG00000051413 +381325 5330438I03Rik MGI:MGI:2685831 +381334 Gal3st2 MGI:MGI:2685834|Ensembl:ENSMUSG00000094651|Vega:OTTMUSG00000048690 +381337 Fam178b MGI:MGI:3026913|Ensembl:ENSMUSG00000046337|Vega:OTTMUSG00000021818 +381338 Lonrf2 MGI:MGI:1920209|Ensembl:ENSMUSG00000048814|Vega:OTTMUSG00000026560 +381339 Tmem182 MGI:MGI:1923725|Ensembl:ENSMUSG00000079588|Vega:OTTMUSG00000042167 +381346 Gm13194 MGI:MGI:3651272 +381347 4930412O13Rik MGI:MGI:1921185 +381350 Spag6 MGI:MGI:3040687|Ensembl:ENSMUSG00000037708|Vega:OTTMUSG00000011474 +381352 Mamdc4 MGI:MGI:2685841|Ensembl:ENSMUSG00000026941|Vega:OTTMUSG00000012159 +381353 Gm996 MGI:MGI:2685842|Ensembl:ENSMUSG00000029419|Vega:OTTMUSG00000012158 +381356 Cacfd1 MGI:MGI:1924317|Ensembl:ENSMUSG00000015488|Vega:OTTMUSG00000011844 +381359 Prdm12 MGI:MGI:2685844|Ensembl:ENSMUSG00000079466|Vega:OTTMUSG00000012078 +381371 Platr26 MGI:MGI:2686477|Ensembl:ENSMUSG00000064263 +381373 Sp9 MGI:MGI:3574660|Ensembl:ENSMUSG00000068859|Vega:OTTMUSG00000013274 +381375 Dfnb59 MGI:MGI:2685847|Ensembl:ENSMUSG00000075267|Vega:OTTMUSG00000013131 +381379 Med19 MGI:MGI:1914234|Ensembl:ENSMUSG00000027080|Vega:OTTMUSG00000013522 +381380 9430088L24Rik MGI:MGI:2686479 +381384 A530006G24Rik MGI:MGI:2685849|Ensembl:ENSMUSG00000051986 +381390 Gm14147 MGI:MGI:3651555|Ensembl:ENSMUSG00000079005|Vega:OTTMUSG00000015802 +381393 4921509C19Rik MGI:MGI:2685851|Ensembl:ENSMUSG00000061525|Vega:OTTMUSG00000015808 +381399 Bpifb4 MGI:MGI:2685852|Ensembl:ENSMUSG00000074665|Vega:OTTMUSG00000016848 +381404 Pabpc1l MGI:MGI:1922908|Ensembl:ENSMUSG00000054582|Vega:OTTMUSG00000016137 +381405 Zfp663 MGI:MGI:2685854|Ensembl:ENSMUSG00000056824|Vega:OTTMUSG00000001118 +381406 Trp53rka MGI:MGI:1918294|Ensembl:ENSMUSG00000039725|Vega:OTTMUSG00000001115 +381409 Cdh26 MGI:MGI:2685856|Ensembl:ENSMUSG00000039155|Vega:OTTMUSG00000016176 +381410 Zfp408 MGI:MGI:2685857|Ensembl:ENSMUSG00000075040|Vega:OTTMUSG00000014301 +381411 Accsl MGI:MGI:3584519|Ensembl:ENSMUSG00000075023|Vega:OTTMUSG00000014992 +381413 Gpr176 MGI:MGI:2685858|Ensembl:ENSMUSG00000040133|Vega:OTTMUSG00000015238 +381417 Gm14085 MGI:MGI:3702173|Ensembl:ENSMUSG00000079071|Vega:OTTMUSG00000015615 +381418 Ctxn2 MGI:MGI:2139444|Ensembl:ENSMUSG00000074872 +381426 A430048G15Rik MGI:MGI:2686486 +381434 C230057A21Rik MGI:MGI:2686488 +381438 Gm5148 MGI:MGI:3646006|Ensembl:ENSMUSG00000058174|Vega:OTTMUSG00000021984 +381452 Gm1647 MGI:MGI:2686493|Ensembl:ENSMUSG00000094763 +381455 6430573P05Rik MGI:MGI:2686494 +381457 Crnn MGI:MGI:2685861|Ensembl:ENSMUSG00000078657|Vega:OTTMUSG00000051912 +381463 Nr1h5 MGI:MGI:3026618|Ensembl:ENSMUSG00000048938|Vega:OTTMUSG00000054722 +381476 Stpg2 MGI:MGI:2685863|Ensembl:ENSMUSG00000047940|Vega:OTTMUSG00000023362 +381481 Samd13 MGI:MGI:2686498 +381482 Gm1653 MGI:MGI:2686499 +381483 Gm5149 MGI:MGI:3648405 +381484 Gm5150 MGI:MGI:3779469|Ensembl:ENSMUSG00000078780|Vega:OTTMUSG00000051090 +381485 Trim55 MGI:MGI:3036269|Ensembl:ENSMUSG00000060913|Vega:OTTMUSG00000051232 +381489 Rxfp1 MGI:MGI:2682211|Ensembl:ENSMUSG00000034009|Vega:OTTMUSG00000044333 +381493 S100a7a MGI:MGI:2687194|Ensembl:ENSMUSG00000063767|Vega:OTTMUSG00000052757 +381498 4930592C13Rik MGI:MGI:2686503|Ensembl:ENSMUSG00000105834 +381510 Dpy19l4 MGI:MGI:2685869|Ensembl:ENSMUSG00000045205|Vega:OTTMUSG00000004592 +381511 Pdp1 MGI:MGI:2685870|Ensembl:ENSMUSG00000049225|Vega:OTTMUSG00000004573 +381522 Ccdc180 MGI:MGI:2685871|Ensembl:ENSMUSG00000035539|Vega:OTTMUSG00000006733 +381524 AI427809 MGI:MGI:2140270|Ensembl:ENSMUSG00000086712 +381530 Mup20 MGI:MGI:3651981|Ensembl:ENSMUSG00000078672|Vega:OTTMUSG00000007485 +381531 Mup21 MGI:MGI:3650630|Ensembl:ENSMUSG00000066153|Vega:OTTMUSG00000000231 +381534 Ube2u MGI:MGI:3588216|Ensembl:ENSMUSG00000069733|Vega:OTTMUSG00000008017 +381535 Gm12800 MGI:MGI:3652120|Ensembl:ENSMUSG00000037028|Vega:OTTMUSG00000008462 +381536 Gm12789 MGI:MGI:3649399|Ensembl:ENSMUSG00000078625|Vega:OTTMUSG00000008445 +381538 Mroh7 MGI:MGI:2685873|Ensembl:ENSMUSG00000047502|Vega:OTTMUSG00000008188 +381544 Gm1661 MGI:MGI:2686507|Ensembl:ENSMUSG00000060268|Vega:OTTMUSG00000009945 +381546 Ccdc24 MGI:MGI:2685874|Ensembl:ENSMUSG00000078588|Vega:OTTMUSG00000008649 +381549 Zfp69 MGI:MGI:107794|Ensembl:ENSMUSG00000064141|Vega:OTTMUSG00000008858 +381560 Xkr8 MGI:MGI:2685877|Ensembl:ENSMUSG00000037752|Vega:OTTMUSG00000009963 +381564 Gm1667 MGI:MGI:2686513 +381569 Gm13084 MGI:MGI:3650237|Ensembl:ENSMUSG00000059218|Vega:OTTMUSG00000010328 +381570 Oog2 MGI:MGI:2684035|Ensembl:ENSMUSG00000066030|Vega:OTTMUSG00000010554 +381572 9430007A20Rik MGI:MGI:2685880|Ensembl:ENSMUSG00000028593|Vega:OTTMUSG00000010536 +381580 Ccdc27 MGI:MGI:2685881|Ensembl:ENSMUSG00000039492|Vega:OTTMUSG00000010504 +381582 Tmem240 MGI:MGI:3648074|Ensembl:ENSMUSG00000084845|Vega:OTTMUSG00000042226 +381590 C87499 MGI:MGI:2140706|Ensembl:ENSMUSG00000038330|Vega:OTTMUSG00000007666 +381591 L1td1 MGI:MGI:3578435|Ensembl:ENSMUSG00000087166|Vega:OTTMUSG00000008672 +381598 2610005L07Rik MGI:MGI:1914283|Ensembl:ENSMUSG00000071793 +381605 Tbc1d2 MGI:MGI:2652885|Ensembl:ENSMUSG00000039813|Vega:OTTMUSG00000006923 +381612 Gm5152 MGI:MGI:3643407 +381622 5031410I06Rik MGI:MGI:3036277|Ensembl:ENSMUSG00000051940|Vega:OTTMUSG00000036613 +381626 Rbm33 MGI:MGI:1919670|Ensembl:ENSMUSG00000048271|Vega:OTTMUSG00000025398 +381628 Adgrf3 MGI:MGI:2685887|Ensembl:ENSMUSG00000067642|Vega:OTTMUSG00000024787 +381629 Atraid MGI:MGI:1918918|Ensembl:ENSMUSG00000013622|Vega:OTTMUSG00000022387 +381633 Gm1673 MGI:MGI:2686519|Ensembl:ENSMUSG00000070858|Vega:OTTMUSG00000025117 +381634 Gm1043 MGI:MGI:2685889|Ensembl:ENSMUSG00000070823|Vega:OTTMUSG00000056275 +381644 Cep135 MGI:MGI:2681869|Ensembl:ENSMUSG00000036403|Vega:OTTMUSG00000026443 +381650 Thap6 MGI:MGI:1922436|Ensembl:ENSMUSG00000102644 +381651 Gm1045 MGI:MGI:2685891|Ensembl:ENSMUSG00000096035|Vega:OTTMUSG00000055583 +381654 C87414 MGI:MGI:2141341|Ensembl:ENSMUSG00000070686|Vega:OTTMUSG00000055758 +381667 Lrcol1 MGI:MGI:2686525|Ensembl:ENSMUSG00000072754|Vega:OTTMUSG00000045089 +381668 Fbrsl1 MGI:MGI:1920907|Ensembl:ENSMUSG00000043323|Vega:OTTMUSG00000054138 +381673 A330070K13Rik MGI:MGI:2685897|Ensembl:ENSMUSG00000052014 +381677 Vgf MGI:MGI:1343180|Ensembl:ENSMUSG00000037428|Vega:OTTMUSG00000049328 +381678 Zcwpw1 MGI:MGI:2685899|Ensembl:ENSMUSG00000037108|Vega:OTTMUSG00000022858 +381680 Nxpe5 MGI:MGI:3584036|Ensembl:ENSMUSG00000047592|Vega:OTTMUSG00000022720 +381686 Kpna7 MGI:MGI:2141165|Ensembl:ENSMUSG00000038770|Vega:OTTMUSG00000022952 +381693 Wdr95 MGI:MGI:1923042|Ensembl:ENSMUSG00000029658|Vega:OTTMUSG00000028834 +381694 B3glct MGI:MGI:2685903|Ensembl:ENSMUSG00000051950|Vega:OTTMUSG00000030598 +381695 N4bp2l2 MGI:MGI:2687207|Ensembl:ENSMUSG00000029655|Vega:OTTMUSG00000027925 +381707 1700069L16Rik MGI:MGI:1920726|Ensembl:ENSMUSG00000042184|Vega:OTTMUSG00000033199 +381714 Gm9758 MGI:MGI:3704245|Ensembl:ENSMUSG00000033219|Vega:OTTMUSG00000025965 +381715 4930572O03Rik MGI:MGI:2441686|Ensembl:ENSMUSG00000069720|Vega:OTTMUSG00000025966 +381716 1700015F17Rik MGI:MGI:2686532|Ensembl:ENSMUSG00000079666|Vega:OTTMUSG00000025941 +381724 BC061212 MGI:MGI:2681870|Ensembl:ENSMUSG00000072822|Vega:OTTMUSG00000030611 +381738 Drc1 MGI:MGI:2685906|Ensembl:ENSMUSG00000073102|Vega:OTTMUSG00000054792 +381741 Lrrc43 MGI:MGI:2685907|Ensembl:ENSMUSG00000063409|Vega:OTTMUSG00000026825 +381759 Wee2 MGI:MGI:3027899|Ensembl:ENSMUSG00000037159|Vega:OTTMUSG00000023198 +381760 Ssbp1 MGI:MGI:1920040|Ensembl:ENSMUSG00000029911|Vega:OTTMUSG00000026906 +381765 LOC381765 - +381776 Igkv2-112 MGI:MGI:3644894|IMGT/GENE-DB:IGKV2-112 +381777 Igkv1-110 MGI:MGI:4439558|IMGT/GENE-DB:IGKV1-110 +381778 Igkv16-104 MGI:MGI:2685913|IMGT/GENE-DB:IGKV16-104 +381782 Igkv4-50 MGI:MGI:2685915|IMGT/GENE-DB:IGKV4-50 +381783 Igkv5-43 MGI:MGI:4943320|IMGT/GENE-DB:IGKV5-43 +381784 Igkv6-25 MGI:MGI:4439867|IMGT/GENE-DB:IGKV6-25 +381785 Gm1070 MGI:MGI:2685916|Ensembl:ENSMUSG00000073018 +381792 2310040G24Rik MGI:MGI:1916897|Ensembl:ENSMUSG00000101655 +381798 4930590J08Rik MGI:MGI:2685917|Ensembl:ENSMUSG00000034063|Vega:OTTMUSG00000058013 +381801 Tatdn2 MGI:MGI:3576210|Ensembl:ENSMUSG00000056952|Vega:OTTMUSG00000024053 +381802 Tsen2 MGI:MGI:2141599|Ensembl:ENSMUSG00000042389|Vega:OTTMUSG00000023781 +381806 Gm10319 MGI:MGI:3643520|Ensembl:ENSMUSG00000071204 +381809 Clec4b2 MGI:MGI:3588267|Ensembl:ENSMUSG00000067767|Vega:OTTMUSG00000027041 +381810 Lpar5 MGI:MGI:2685918|Ensembl:ENSMUSG00000067714|Vega:OTTMUSG00000022555 +381812 Cracr2a MGI:MGI:2685919|Ensembl:ENSMUSG00000061414|Vega:OTTMUSG00000022660 +381813 Prmt8 MGI:MGI:3043083|Ensembl:ENSMUSG00000030350|Vega:OTTMUSG00000020414 +381816 4922502D21Rik MGI:MGI:2685920|Ensembl:ENSMUSG00000047720|Vega:OTTMUSG00000026990 +381818 Gm5154 MGI:MGI:3646668 +381819 A630073D07Rik MGI:MGI:2686534|Ensembl:ENSMUSG00000067541|Vega:OTTMUSG00000056950 +381820 Smim10l1 MGI:MGI:1914379|Ensembl:ENSMUSG00000072704|Vega:OTTMUSG00000046846 +381822 Lockd MGI:MGI:1915081|Ensembl:ENSMUSG00000098318 +381823 Apold1 MGI:MGI:2685921|Ensembl:ENSMUSG00000090698|Vega:OTTMUSG00000057080 +381827 1700073E17Rik MGI:MGI:1920734 +381831 Igkv4-58 MGI:MGI:2685923|IMGT/GENE-DB:IGKV4-58 +381832 Prpmp5 MGI:MGI:1927478|Ensembl:ENSMUSG00000107874|Vega:OTTMUSG00000034590 +381833 Prb1 MGI:MGI:2681872|Ensembl:ENSMUSG00000067543|Vega:OTTMUSG00000056796 +381835 Sbk3 MGI:MGI:2685924|Ensembl:ENSMUSG00000085272|Vega:OTTMUSG00000033734 +381836 Sbk2 MGI:MGI:2685925|Ensembl:ENSMUSG00000030433|Vega:OTTMUSG00000043614 +381838 Vmn2r43 MGI:MGI:3037819|Ensembl:ENSMUSG00000053720|Vega:OTTMUSG00000042466 +381845 Rnf225 MGI:MGI:1924198|Ensembl:ENSMUSG00000033967|Vega:OTTMUSG00000060830 +381852 Gm5155 MGI:MGI:3647191 +381853 Gipr MGI:MGI:1352753|Ensembl:ENSMUSG00000030406|Vega:OTTMUSG00000058589 +381867 Ovol3 MGI:MGI:2388075|Ensembl:ENSMUSG00000100512|Vega:OTTMUSG00000047918 +381884 Slc6a16 MGI:MGI:2685930|Ensembl:ENSMUSG00000094152|Vega:OTTMUSG00000059240 +381886 Mrgpra6 MGI:MGI:3033107 +381903 Alg8 MGI:MGI:2141959|Ensembl:ENSMUSG00000035704|Vega:OTTMUSG00000029538 +381914 B230311B06Rik MGI:MGI:2686541|Ensembl:ENSMUSG00000109284 +381917 Dnah3 MGI:MGI:2683040|Ensembl:ENSMUSG00000052273|Vega:OTTMUSG00000059177 +381921 Taok2 MGI:MGI:1915919|Ensembl:ENSMUSG00000059981|Vega:OTTMUSG00000032464 +381922 D830044I16Rik MGI:MGI:2443610 +381924 Itgad MGI:MGI:3578624|Ensembl:ENSMUSG00000070369|Vega:OTTMUSG00000042024 +381925 Plpp4 MGI:MGI:2685936|Ensembl:ENSMUSG00000070366|Vega:OTTMUSG00000058759 +381933 6430531B16Rik MGI:MGI:2685939|Ensembl:ENSMUSG00000073795|Vega:OTTMUSG00000031693 +381937 Gm5157 MGI:MGI:3648211|Ensembl:ENSMUSG00000101436|Vega:OTTMUSG00000045830 +381944 Usp17lb MGI:MGI:3051498|Ensembl:ENSMUSG00000062369|Vega:OTTMUSG00000060829 +381959 Gm1096 MGI:MGI:2685942 +381967 Gm26705 MGI:MGI:5477199|Ensembl:ENSMUSG00000097015 +381970 Scgb2b2 MGI:MGI:3042579|Ensembl:ENSMUSG00000036521|Vega:OTTMUSG00000027202 +381974 Mrgprg MGI:MGI:3033145|Ensembl:ENSMUSG00000050276|Vega:OTTMUSG00000060032 +381979 Brsk1 MGI:MGI:2685946|Ensembl:ENSMUSG00000035390|Vega:OTTMUSG00000026253 +381983 Lmtk3 MGI:MGI:3039582|Ensembl:ENSMUSG00000062044|Vega:OTTMUSG00000029694 +381990 Zbtb2 MGI:MGI:2685949|Ensembl:ENSMUSG00000075327|Vega:OTTMUSG00000063495 +381994 E030018B13Rik MGI:MGI:2686543|Ensembl:ENSMUSG00000095061|Vega:OTTMUSG00000057935 +382000 AY761184 MGI:MGI:3611585|Ensembl:ENSMUSG00000058618|Vega:OTTMUSG00000019927 +382003 Gm1698 MGI:MGI:2686544 +382007 Adam26b MGI:MGI:3588304|Ensembl:ENSMUSG00000063900|Vega:OTTMUSG00000061170 +382010 Cep44 MGI:MGI:3525111|Ensembl:ENSMUSG00000038215|Vega:OTTMUSG00000032837 +382014 Ano8 MGI:MGI:2687327|Ensembl:ENSMUSG00000034863|Vega:OTTMUSG00000062157 +382018 Unc13a MGI:MGI:3051532|Ensembl:ENSMUSG00000034799|Vega:OTTMUSG00000040153 +382019 Zfp882 MGI:MGI:3642748|Ensembl:ENSMUSG00000089857|Vega:OTTMUSG00000022410 +382030 Cnep1r1 MGI:MGI:1921981|Ensembl:ENSMUSG00000036810|Vega:OTTMUSG00000031497 +382034 Gse1 MGI:MGI:1098275|Ensembl:ENSMUSG00000031822|Vega:OTTMUSG00000031594 +382035 Pabpn1l MGI:MGI:2685954|Ensembl:ENSMUSG00000069867|Vega:OTTMUSG00000020627 +382036 A530010L16Rik MGI:MGI:3037766 +382038 Urb2 MGI:MGI:2681124|Ensembl:ENSMUSG00000031976|Vega:OTTMUSG00000037006 +382044 Ces1b MGI:MGI:3779470|Ensembl:ENSMUSG00000078964|Vega:OTTMUSG00000061541 +382045 Adgrg5 MGI:MGI:2685955|Ensembl:ENSMUSG00000061577|Vega:OTTMUSG00000022407 +382051 Pdp2 MGI:MGI:1918878|Ensembl:ENSMUSG00000048371|Vega:OTTMUSG00000061951 +382052 Gm5159 MGI:MGI:3648109 +382053 Ces3a MGI:MGI:102773|Ensembl:ENSMUSG00000069922|Vega:OTTMUSG00000061993 +382056 Crtc1 MGI:MGI:2142523|Ensembl:ENSMUSG00000003575|Vega:OTTMUSG00000022258 +382059 Defa22 MGI:MGI:3639039|Ensembl:ENSMUSG00000074443|Vega:OTTMUSG00000019763 +382062 AB124611 MGI:MGI:3043001|Ensembl:ENSMUSG00000057191|Vega:OTTMUSG00000038084 +382064 Gm1110 MGI:MGI:2685956|Ensembl:ENSMUSG00000079644|Vega:OTTMUSG00000062678 +382066 Prdm10 MGI:MGI:2682952|Ensembl:ENSMUSG00000042496|Vega:OTTMUSG00000031586 +382069 Gm1113 MGI:MGI:2685959 +382073 Ccdc84 MGI:MGI:2685960|Ensembl:ENSMUSG00000043923|Vega:OTTMUSG00000063303 +382074 Foxr1 MGI:MGI:2685961|Ensembl:ENSMUSG00000074397|Vega:OTTMUSG00000063305 +382075 Odf3l1 MGI:MGI:2681875|Ensembl:ENSMUSG00000045620|Vega:OTTMUSG00000063131 +382077 Ccdc33 MGI:MGI:1922464|Ensembl:ENSMUSG00000037716|Vega:OTTMUSG00000030816 +382083 Snx22 MGI:MGI:2685966|Ensembl:ENSMUSG00000039452|Vega:OTTMUSG00000062642 +382088 Omt2b MGI:MGI:106619|Ensembl:ENSMUSG00000038750|Vega:OTTMUSG00000047888 +382089 Ripply2 MGI:MGI:2685968|Ensembl:ENSMUSG00000047897|Vega:OTTMUSG00000045052 +382090 Cep162 MGI:MGI:1925343|Ensembl:ENSMUSG00000056919|Vega:OTTMUSG00000025816 +382096 Gm5160 MGI:MGI:3648528 +382097 Gm1123 MGI:MGI:2685969|Ensembl:ENSMUSG00000044860|Vega:OTTMUSG00000048180 +382099 Gm5161 MGI:MGI:3648529 +382105 Fbxw15 MGI:MGI:3505701|Ensembl:ENSMUSG00000074060|Vega:OTTMUSG00000027449 +382106 Fbxw24 MGI:MGI:3646659|Ensembl:ENSMUSG00000062275|Vega:OTTMUSG00000051230 +382109 Fbxw26 MGI:MGI:3646662|Ensembl:ENSMUSG00000059547|Vega:OTTMUSG00000051231 +382111 Susd5 MGI:MGI:2685972|Ensembl:ENSMUSG00000086596|Vega:OTTMUSG00000062513 +382113 Slc22a14 MGI:MGI:2685974|Ensembl:ENSMUSG00000070280|Vega:OTTMUSG00000027480 +382114 D830035M03Rik MGI:MGI:2686558|Ensembl:ENSMUSG00000111828 +382117 Tcaim MGI:MGI:1196217|Ensembl:ENSMUSG00000046603|Vega:OTTMUSG00000031595 +382118 Zkscan7 MGI:MGI:3040678|Ensembl:ENSMUSG00000063488|Vega:OTTMUSG00000062789 +382131 Gm20737 MGI:MGI:5434093|Ensembl:ENSMUSG00000095950|Vega:OTTMUSG00000046762 +382133 Gm20738 MGI:MGI:5434094|Ensembl:ENSMUSG00000094575|Vega:OTTMUSG00000047634 +382137 Fdxacb1 MGI:MGI:3584513|Ensembl:ENSMUSG00000037845|Vega:OTTMUSG00000042099 +382139 Gm1715 MGI:MGI:2686561|Ensembl:ENSMUSG00000111020 +382156 Fbxw22 MGI:MGI:3643290|Ensembl:ENSMUSG00000070324|Vega:OTTMUSG00000051226 +382161 Gm5165 MGI:MGI:3646034 +382180 Trav7d-4 MGI:MGI:3651273|IMGT/GENE-DB:TRAV7D-4 +382202 LOC382202 - +382206 Ssx9 MGI:MGI:2446773|Ensembl:ENSMUSG00000035371|Vega:OTTMUSG00000016719 +382207 Jade3 MGI:MGI:2148019|Ensembl:ENSMUSG00000037315|Vega:OTTMUSG00000017083 +382209 Rhox3a MGI:MGI:2676626|Ensembl:ENSMUSG00000071772|Vega:OTTMUSG00000017119 +382217 Gm1140 MGI:MGI:2685986|Ensembl:ENSMUSG00000079578|Vega:OTTMUSG00000017721 +382221 Gm1141 MGI:MGI:2685987|Ensembl:ENSMUSG00000073130|Vega:OTTMUSG00000017815 +382231 8030474K03Rik MGI:MGI:2685988|Ensembl:ENSMUSG00000046774|Vega:OTTMUSG00000018193 +382233 Gm5166 MGI:MGI:3648097 +382236 Brwd3 MGI:MGI:3029414|Ensembl:ENSMUSG00000063663|Vega:OTTMUSG00000018333 +382239 Cpxcr1 MGI:MGI:2685989|Ensembl:ENSMUSG00000072995|Vega:OTTMUSG00000018451 +382243 Gm10439 MGI:MGI:3710525|Ensembl:ENSMUSG00000072923|Vega:OTTMUSG00000018971 +382244 Gm15091 MGI:MGI:3712222|Ensembl:ENSMUSG00000095082|Vega:OTTMUSG00000018981 +382245 Tmem29 MGI:MGI:1923420|Ensembl:ENSMUSG00000041353|Vega:OTTMUSG00000018995 +382252 A830080D01Rik MGI:MGI:2685992|Ensembl:ENSMUSG00000044150|Vega:OTTMUSG00000019441 +382253 Cdkl5 MGI:MGI:1278336|Ensembl:ENSMUSG00000031292|Vega:OTTMUSG00000019591 +382255 Gm1720 MGI:MGI:2686566|Ensembl:ENSMUSG00000086860 +382265 Cldn34c3 MGI:MGI:3645501|Ensembl:ENSMUSG00000094620 +382275 Gm5168 MGI:MGI:3703318|Ensembl:ENSMUSG00000079655|Vega:OTTMUSG00000017012 +382277 Gm5169 MGI:MGI:3804938|Ensembl:ENSMUSG00000096620 +382282 Rhox12 MGI:MGI:2685994|Ensembl:ENSMUSG00000071766|Vega:OTTMUSG00000017178 +382301 Sly MGI:MGI:2687328|Ensembl:ENSMUSG00000101155|Vega:OTTMUSG00000045354 +382342 Tpi-rs5 MGI:MGI:98803 +382348 Taar8b MGI:MGI:2685995|Ensembl:ENSMUSG00000100186|Vega:OTTMUSG00000019209 +382354 Gm5171 MGI:MGI:3642952 +382364 Gm1153 MGI:MGI:2685999 +382384 Odf3l2 MGI:MGI:2686003|Ensembl:ENSMUSG00000035963 +382388 Gm5173 MGI:MGI:3642939 +382395 Gm5174 MGI:MGI:3646116 +382406 Poc1b MGI:MGI:1918511|Ensembl:ENSMUSG00000019952|Vega:OTTMUSG00000032479 +382407 Gad1-ps MGI:MGI:95633 +382413 Gm5175 MGI:MGI:3647142 +382421 Gm5176 MGI:MGI:3644450|Ensembl:ENSMUSG00000111997 +382423 Atxn7l3b MGI:MGI:1914971|Ensembl:ENSMUSG00000074748|Vega:OTTMUSG00000035375 +382427 Best3 MGI:MGI:3580298|Ensembl:ENSMUSG00000020169 +382450 Gm5177 MGI:MGI:3646657|Ensembl:ENSMUSG00000098065 +382457 Gm5178 MGI:MGI:3646661 +382471 Gm5181 MGI:MGI:3646914 +382473 Gm11949 MGI:MGI:3650314 +382478 Gm11962 MGI:MGI:3652247 +382483 Gm11996 MGI:MGI:3650898 +382486 Gm12015 MGI:MGI:3651373 +382494 Rpl15-ps1 MGI:MGI:3652079 +382504 Rpsa-ps5 MGI:MGI:3650550 +382508 Gm12136 MGI:MGI:3651746 +382510 Gm12161 MGI:MGI:3649484 +382518 Gm12201 MGI:MGI:3650183 +382522 Hist3h2bb-ps MGI:MGI:1922442|Ensembl:ENSMUSG00000080712 +382523 Gm12260 MGI:MGI:3651326 +382532 Gm12308 MGI:MGI:3650268 +382536 Gm12321 MGI:MGI:3651559 +382543 Ankfn1 MGI:MGI:2686021|Ensembl:ENSMUSG00000047773|Vega:OTTMUSG00000001319 +382545 Gm11501 MGI:MGI:3650728 +382551 Cd300ld3 MGI:MGI:2687214|Ensembl:ENSMUSG00000069607|Vega:OTTMUSG00000003607 +382562 Pfn4 MGI:MGI:1920121|Ensembl:ENSMUSG00000020639 +382567 Gm5182 MGI:MGI:3649174 +382571 Kcnf1 MGI:MGI:2687399|Ensembl:ENSMUSG00000051726|Vega:OTTMUSG00000037668 +382600 Gm5183 MGI:MGI:3647559 +382601 Gm5184 MGI:MGI:3647558 +382606 Gm5185 MGI:MGI:3647557 +382620 Tmed8 MGI:MGI:1923480|Ensembl:ENSMUSG00000034111 +382626 Gm5186 MGI:MGI:3647307 +382635 Gm5187 MGI:MGI:3644132 +382639 Zbtb42 MGI:MGI:3644133|Ensembl:ENSMUSG00000037638|Vega:OTTMUSG00000037611 +382640 Gm5189 MGI:MGI:3647067 +382645 Gm5190 MGI:MGI:3647068 +382686 3110053B16Rik MGI:MGI:1920435 +382692 Ighv1-19 MGI:MGI:4439779|IMGT/GENE-DB:IGHV1-19 +382693 LOC382693 - +382695 Ighv1-56 MGI:MGI:4439715|IMGT/GENE-DB:IGHV1-56 +382696 Ighv1-52 MGI:MGI:4439752|IMGT/GENE-DB:IGHV-1-52 +382722 Gm5191 MGI:MGI:3646226 +382723 Rpl10a-ps2 MGI:MGI:3646227 +382740 Gm11307 MGI:MGI:3650171 +382743 Gm5194 MGI:MGI:3645611 +382747 Gm5195 MGI:MGI:3645612 +382769 Cbx3-ps4 MGI:MGI:3645820 +382770 Vmn2r-ps105 MGI:MGI:3040709 +382780 Gm5197 MGI:MGI:3779472 +382792 Gm5199 MGI:MGI:3643997 +382793 Mtx3 MGI:MGI:2686040|Ensembl:ENSMUSG00000021704 +382807 Gm5200 MGI:MGI:3646335 +382823 Atp5c1-ps MGI:MGI:2145515 +382843 Rpl21-ps4 MGI:MGI:3646825 +382844 Rpl19-ps4 MGI:MGI:3646824 +382864 Colq MGI:MGI:1338761|Ensembl:ENSMUSG00000057606|Vega:OTTMUSG00000033849 +382867 Zfp488 MGI:MGI:2686052|Ensembl:ENSMUSG00000044519|Vega:OTTMUSG00000035273 +382871 Gm5203 MGI:MGI:3643899 +382872 Gm5204 MGI:MGI:3643898 +382876 Gm5205 MGI:MGI:3643900 +382884 Gm5206 MGI:MGI:3645516 +382913 Neil2 MGI:MGI:2686058|Ensembl:ENSMUSG00000035121 +382919 Gm17740 MGI:MGI:5009816 +382931 Gm5207 MGI:MGI:3647978 +382936 Hspd1-ps5 MGI:MGI:3648220 +382943 Gm17741 MGI:MGI:5009817 +382947 Gm5209 MGI:MGI:3645093 +382969 Gm5210 MGI:MGI:3644379 +382975 Gm5212 MGI:MGI:3647582 +382985 Rrm2b MGI:MGI:2155865|Ensembl:ENSMUSG00000022292|Vega:OTTMUSG00000032790 +382986 Gm5213 MGI:MGI:3779473 +382988 Gm5214 MGI:MGI:3645822 +383032 Gm5215 MGI:MGI:3644834 +383050 Gm5216 MGI:MGI:3645017 +383051 Gm5217 MGI:MGI:3645016 +383075 Enthd1 MGI:MGI:2686088|Ensembl:ENSMUSG00000050439 +383080 Gm5218 MGI:MGI:3646583 +383094 Gm5219 MGI:MGI:3779474 +383103 Tvp23a MGI:MGI:3665441|Ensembl:ENSMUSG00000050908|Vega:OTTMUSG00000025762 +383118 Zfp520-ps MGI:MGI:1343185 +383172 Rps19-ps12 MGI:MGI:3645928 +383186 Gm5221 MGI:MGI:3648101 +383211 Gm5223 MGI:MGI:3644871 +383218 Gm5224 MGI:MGI:3647439 +383225 Gm5225 MGI:MGI:3779476 +383229 Hba-ps4 MGI:MGI:96018 +383240 Rpl9-ps9 MGI:MGI:3643803 +383243 Olfr128 MGI:MGI:2177511|Ensembl:ENSMUSG00000059030|Vega:OTTMUSG00000037340 +383250 Mif-ps8 MGI:MGI:103167 +383258 Vmn2r118 MGI:MGI:3761695|Ensembl:ENSMUSG00000091504|Vega:OTTMUSG00000039969 +383275 Gm5229 MGI:MGI:3646699 +383277 Gm5230 MGI:MGI:3646698 +383282 Gm5231 MGI:MGI:3643308 +383295 Ypel5 MGI:MGI:1916937|Ensembl:ENSMUSG00000039770 +383297 Gm5232 MGI:MGI:3646457 +383318 Gm5234 MGI:MGI:3645138 +383325 Gm5236 MGI:MGI:3648556 +383326 Gm5237 MGI:MGI:3779477 +383339 Gm5238 MGI:MGI:3645313 +383341 Gm5239 MGI:MGI:3648788 +383348 Kctd16 MGI:MGI:1914659|Ensembl:ENSMUSG00000051401 +383354 Gm5240 MGI:MGI:3645528 +383374 Gm10557 MGI:MGI:3708638 +383420 Gm5241 MGI:MGI:3643812 +383424 Gm5242 MGI:MGI:3779478 +383435 Ms4a14 MGI:MGI:2686122|Ensembl:ENSMUSG00000099398|Vega:OTTMUSG00000047100 +383436 Gm5244 MGI:MGI:3646958 +383438 Rpl37-ps1 MGI:MGI:3646957 +383440 Rpl29-ps6 MGI:MGI:3779480 +383450 Gm5246 MGI:MGI:3646252 +383464 Gm5248 MGI:MGI:3643322 +383474 Gm5249 MGI:MGI:3646471 +383490 Gm5250 MGI:MGI:3647667 +383491 Prdm14 MGI:MGI:3588194|Ensembl:ENSMUSG00000042414|Vega:OTTMUSG00000017097 +383495 Gm5251 MGI:MGI:3647666 +383499 Gm5252 MGI:MGI:3647664 +383504 Gm5253 MGI:MGI:3779481 +383509 Gm5254 MGI:MGI:3645015 +383520 Gm5255 MGI:MGI:3779482 +383528 Gm5256 MGI:MGI:3644836 +383531 Gm5257 MGI:MGI:3647791 +383538 Gm5258 MGI:MGI:3647794 +383542 Gm5259 MGI:MGI:3644613 +383546 Gm5260 MGI:MGI:3644614 +383548 Serpinb3b MGI:MGI:2683293|Ensembl:ENSMUSG00000073602|Vega:OTTMUSG00000021003 +383559 Gm5261 MGI:MGI:3647593 +383563 Gpr25 MGI:MGI:2686146|Ensembl:ENSMUSG00000052759|Vega:OTTMUSG00000049849 +383570 Gm5262 MGI:MGI:3647342 +383571 Gm5263 MGI:MGI:3647343 +383592 Kif28 MGI:MGI:2686151|Ensembl:ENSMUSG00000087236|Vega:OTTMUSG00000033760 +383603 Gm5264 MGI:MGI:3646340 +383613 Gm5265 MGI:MGI:3643416 +383619 Aim2 MGI:MGI:2686159|Ensembl:ENSMUSG00000037860|Vega:OTTMUSG00000033253 +383629 Gm5266 MGI:MGI:3646119 +383634 Gm5267 MGI:MGI:3643178 +383640 Gm5268 MGI:MGI:3646790 +383644 Gm5269 MGI:MGI:3646793 +383650 Psmb6-ps2 MGI:MGI:109264 +383665 Gm13326 MGI:MGI:3650196 +383678 Obp2b MGI:MGI:3651927|Ensembl:ENSMUSG00000079539|Vega:OTTMUSG00000012631 +383690 Gm13469 MGI:MGI:3649386 +383691 Gm13472 MGI:MGI:3649391 +383705 Gm13592 MGI:MGI:3650915 +383706 Rpl35-ps1 MGI:MGI:3651404 +383707 Gm13600 MGI:MGI:3649282 +383709 Gm1322 MGI:MGI:2686168 +383712 Eif1-ps3 MGI:MGI:3651806 +383717 Gm14460 MGI:MGI:3651590 +383725 Gm13702 MGI:MGI:3651725 +383735 Gm13870 MGI:MGI:3650544 +383739 Gm13904 MGI:MGI:3651201 +383752 Gm14108 MGI:MGI:3649327 +383753 Gm1330 MGI:MGI:2686176 +383754 Gm14132 MGI:MGI:3652226 +383766 Tldc2 MGI:MGI:2686178|Ensembl:ENSMUSG00000074628|Vega:OTTMUSG00000016172 +383769 Gm5270 MGI:MGI:3647658 +383770 Gm11449 MGI:MGI:3651346 +383773 Gm11469 MGI:MGI:3650291 +383774 Gm11470 MGI:MGI:3649221 +383783 Gm1335 MGI:MGI:2686181 +383787 Ankrd63 MGI:MGI:2686183|Ensembl:ENSMUSG00000078137|Vega:OTTMUSG00000015370 +383791 Gm14006 MGI:MGI:3652192 +383801 Rpl23a-ps4 MGI:MGI:3651728 +383815 Rps24-ps2 MGI:MGI:3649025 +383818 Gm5272 MGI:MGI:3649019 +383820 5330432E05Rik MGI:MGI:3642332 +383849 Gm5274 MGI:MGI:3646161 +383850 Rpl23a-ps5 MGI:MGI:3643228 +383862 Gm5276 MGI:MGI:3646382 +383883 Gm5277 MGI:MGI:3646590 +383887 Gm17742 MGI:MGI:5009818 +383891 Gm5278 MGI:MGI:3643701 +383901 Gm5279 MGI:MGI:3647225 +383905 Utp14b-ps1 MGI:MGI:3051682 +383923 Gm5281 MGI:MGI:3779483 +383927 Gm17743 MGI:MGI:5009819 +383936 Gm5283 MGI:MGI:3643834 +383940 LOC383940 - +383949 Gm5284 MGI:MGI:3646209 +383956 Gm5285 MGI:MGI:3644519 +383977 Gm5286 MGI:MGI:3644284 +383991 Gm12920 MGI:MGI:3652000 +383992 Rps11-ps3 MGI:MGI:3649802 +383994 Gm11864 MGI:MGI:3650454 +383998 Gm11889 MGI:MGI:3651112 +384001 Prdx6-ps2 MGI:MGI:1203519 +384007 Gm12389 MGI:MGI:3650084 +384009 Glipr2 MGI:MGI:1917770|Ensembl:ENSMUSG00000028480|Vega:OTTMUSG00000007145 +384015 Gm12461 MGI:MGI:3650438 +384018 Gm12479 MGI:MGI:3651218 +384021 Mup-ps15 MGI:MGI:3652152 +384033 Gm12792 MGI:MGI:3649402 +384038 Gm12727 MGI:MGI:3649747 +384039 Hspd1-ps4 MGI:MGI:3649750 +384042 Gm12834 MGI:MGI:3649428 +384052 Gm12957 MGI:MGI:3649304 +384059 Tlr12 MGI:MGI:3045221|Ensembl:ENSMUSG00000062545|Vega:OTTMUSG00000009457 +384061 Fndc5 MGI:MGI:1917614|Ensembl:ENSMUSG00000001334|Vega:OTTMUSG00000009621 +384071 Slc25a34 MGI:MGI:2686215|Ensembl:ENSMUSG00000040740|Vega:OTTMUSG00000010347 +384077 Pramel5 MGI:MGI:2156389|Ensembl:ENSMUSG00000036749|Vega:OTTMUSG00000010540 +384081 Gm13249 MGI:MGI:3649659 +384084 Gm13246 MGI:MGI:3649657 +384087 Gm13146 MGI:MGI:3651742 +384091 Gm13092 MGI:MGI:3649661 +384106 Gm12692 MGI:MGI:3651859 +384113 Gm5287 MGI:MGI:3648217 +384125 Gm12642 MGI:MGI:3649275 +384144 Gm5288 MGI:MGI:3648495 +384148 Dnd1-ps MGI:MGI:3648488 +384174 Gm5291 MGI:MGI:3645662 +384179 Gm5292 MGI:MGI:3645663 +384185 Arl9 MGI:MGI:1915496|Ensembl:ENSMUSG00000063820|Vega:OTTMUSG00000026996 +384198 Fam47e MGI:MGI:2686227|Ensembl:ENSMUSG00000057068|Vega:OTTMUSG00000033049 +384214 Ephx4 MGI:MGI:2686228|Ensembl:ENSMUSG00000033805|Vega:OTTMUSG00000023959 +384219 Vmn2r11 MGI:MGI:3643806|Ensembl:ENSMUSG00000091450|Vega:OTTMUSG00000039860 +384220 Vmn2r16 MGI:MGI:3647194|Ensembl:ENSMUSG00000092080|Vega:OTTMUSG00000039866 +384221 Vmn2r17 MGI:MGI:3647193|Ensembl:ENSMUSG00000091879|Vega:OTTMUSG00000039868 +384244 Gm5294 MGI:MGI:3646467|Ensembl:ENSMUSG00000094504|Vega:OTTMUSG00000054735 +384261 Gm5296 MGI:MGI:3822457 +384275 Gm5297 MGI:MGI:3646414 +384281 Gatc MGI:MGI:1923776|Ensembl:ENSMUSG00000029536|Vega:OTTMUSG00000014655 +384308 Gm5298 MGI:MGI:3645526 +384309 Trim56 MGI:MGI:2685298|Ensembl:ENSMUSG00000043279|Vega:OTTMUSG00000023415 +384350 Gm5300 MGI:MGI:3642954 +384356 Gm5301 MGI:MGI:3642953 +384358 Gm5302 MGI:MGI:3642956 +384360 Gm5303 MGI:MGI:3647388 +384363 Gm1401 MGI:MGI:2686247 +384379 Rpl31-ps7 MGI:MGI:3648986 +384383 Gm5305 MGI:MGI:3644734 +384386 Gm5306 MGI:MGI:3644732 +384398 Gm5307 MGI:MGI:3647907 +384401 Gm5308 MGI:MGI:3646418 +384405 Gm5309 MGI:MGI:3646419 +384408 Gm5310 MGI:MGI:3646417 +384410 Igkv4-92 MGI:MGI:2686254|IMGT/GENE-DB:IGKV4-92 +384411 Igkv12-89 MGI:MGI:4439829|IMGT/GENE-DB:IGKV12-89 +384417 Igkv5-37 MGI:MGI:2686256|IMGT/GENE-DB:IGKV5-37 +384419 Igkv8-30 MGI:MGI:3642250|IMGT/GENE-DB:IGKV8-30 +384422 Igk-V8 MGI:MGI:96518 +384440 Gm5311 MGI:MGI:3646896 +384450 Gm5312 MGI:MGI:3643752 +384452 Noto MGI:MGI:3053002|Ensembl:ENSMUSG00000068302|Vega:OTTMUSG00000037550 +384461 Gm5313 MGI:MGI:3646641 +384466 Gm5314 MGI:MGI:3646639 +384470 Gm5315 MGI:MGI:3643497 +384482 Gm5316 MGI:MGI:3645576 +384484 Gm5317 MGI:MGI:3645578 +384486 Vmn2r-ps33 MGI:MGI:3761515 +384494 Gm5318 MGI:MGI:3648613 +384514 Igkv4-57-1 MGI:MGI:2686264|IMGT/GENE-DB:IGKV4-57-1 +384515 Igkv4-68 MGI:MGI:2686265|IMGT/GENE-DB:IGKV4-68 +384521 Gm5319 MGI:MGI:3645267 +384522 Vmn1r55 MGI:MGI:3033474|Ensembl:ENSMUSG00000074402|Vega:OTTMUSG00000037735 +384524 Gm5320 MGI:MGI:3645265 +384525 Gm5321 MGI:MGI:3645266 +384534 Vmn2r52 MGI:MGI:3695443|Ensembl:ENSMUSG00000091930|Vega:OTTMUSG00000038509 +384557 Ceacam3 MGI:MGI:3646296|Ensembl:ENSMUSG00000053228|Vega:OTTMUSG00000022042 +384560 Gm5322 MGI:MGI:3645680 +384569 Nova2 MGI:MGI:104296|Ensembl:ENSMUSG00000030411|Vega:OTTMUSG00000036901 +384572 Vmn1r177 MGI:MGI:3033481|Ensembl:ENSMUSG00000057513|Vega:OTTMUSG00000038011 +384573 Vmn1r-ps85 MGI:MGI:3648935 +384575 Gm5324 MGI:MGI:3648933 +384585 Scgb1b3 MGI:MGI:3644233|Ensembl:ENSMUSG00000095257|Vega:OTTMUSG00000045681 +384589 Scgb1b29 MGI:MGI:3644231|Ensembl:ENSMUSG00000078757|Vega:OTTMUSG00000037049 +384591 Gm5327 MGI:MGI:3647424 +384594 Gm5329 MGI:MGI:3647426 +384605 Wdr88 MGI:MGI:2686275 +384619 Ccdc155 MGI:MGI:2687329|Ensembl:ENSMUSG00000038292|Vega:OTTMUSG00000027233 +384622 Gm5331 MGI:MGI:3647739 +384631 Gm5333 MGI:MGI:3644550 +384639 Gm5334 MGI:MGI:3644545 +384643 Gm5335 MGI:MGI:3647920 +384647 Gm15544 MGI:MGI:3782993 +384658 Gm5338 MGI:MGI:3644750 +384695 Vmn1r123 MGI:MGI:2686292|Ensembl:ENSMUSG00000094385|Vega:OTTMUSG00000038160 +384696 Vmn1r119 MGI:MGI:2686293|Ensembl:ENSMUSG00000094010|Vega:OTTMUSG00000038154 +384699 Gm5339 MGI:MGI:3645143 +384701 Usp17ld MGI:MGI:3051372|Ensembl:ENSMUSG00000057321|Vega:OTTMUSG00000019025 +384703 Olfr670 MGI:MGI:3030504|Ensembl:ENSMUSG00000044705|Vega:OTTMUSG00000060550 +384710 Gm5340 MGI:MGI:3779484 +384719 Gm5341 MGI:MGI:3644965 +384724 Cyp2t4 MGI:MGI:2686296|Ensembl:ENSMUSG00000078787|Vega:OTTMUSG00000023177 +384732 Olfr715b MGI:MGI:3647188|Ensembl:ENSMUSG00000062987|Vega:OTTMUSG00000059737 +384741 Gm5342 MGI:MGI:3647517 +384752 Nlrp4d MGI:MGI:3056574 +384763 Zfp667 MGI:MGI:2442757|Ensembl:ENSMUSG00000054893|Vega:OTTMUSG00000022340 +384775 1700003H04Rik MGI:MGI:1923637|Ensembl:ENSMUSG00000039174|Vega:OTTMUSG00000042340 +384782 Rps16-ps3 MGI:MGI:3647039 +384783 Irs2 MGI:MGI:109334|Ensembl:ENSMUSG00000038894|Vega:OTTMUSG00000059106 +384806 Adam20 MGI:MGI:2152342|Ensembl:ENSMUSG00000046282|Vega:OTTMUSG00000032841 +384808 Gm5345 MGI:MGI:3644320 +384813 Gm5346 MGI:MGI:3647273|Ensembl:ENSMUSG00000050190|Vega:OTTMUSG00000061172 +384814 Gm5347 MGI:MGI:3647274 +384817 4930448N21Rik MGI:MGI:1926155 +384830 Hspd1-ps2 MGI:MGI:3647040 +384831 Gm5350 MGI:MGI:3647041 +384845 Umpk-ps MGI:MGI:1278338 +384852 Gm5354 MGI:MGI:3646767 +384857 Gm5355 MGI:MGI:3646765 +384862 Gm5356 MGI:MGI:3643649 +384864 Gm1943 MGI:MGI:3037801 +384868 Gm5357 MGI:MGI:3643650 +384873 Gm5358 MGI:MGI:3646543 +384883 Gm5359 MGI:MGI:3643393 +384895 Gm5361 MGI:MGI:3646323 +384911 Gm5362 MGI:MGI:3646009 +384912 Gm5363 MGI:MGI:3646008 +384926 Tpi-rs4 MGI:MGI:98802 +384929 Gm1947 MGI:MGI:3037805 +384931 Gm5364 MGI:MGI:3646198 +384954 Gm5366 MGI:MGI:3646412 +384962 Gm5368 MGI:MGI:3648849 +384967 Gm5369 MGI:MGI:3648848 +384968 Gm5370 MGI:MGI:3648852 +384971 Gm5371 MGI:MGI:3645791 +384978 Gm5372 MGI:MGI:3645790 +384997 Pglyrp4 MGI:MGI:2686324|Ensembl:ENSMUSG00000042250|Vega:OTTMUSG00000022770 +385024 Gm5373 MGI:MGI:3779485 +385047 Trav6d-7 MGI:MGI:2686335|IMGT/GENE-DB:TRAV6D-7 +385049 Gm5374 MGI:MGI:3779486 +385109 Igkv4-72 MGI:MGI:2686345|IMGT/GENE-DB:IGKV4-72 +385120 Igkv4-70 MGI:MGI:2686348|IMGT/GENE-DB:IGKV4-70 +385138 BC061237 MGI:MGI:2682320|Ensembl:ENSMUSG00000072145|Vega:OTTMUSG00000034661 +385199 Rpl18a-ps4 MGI:MGI:3648821 +385211 Zfp986 MGI:MGI:3649925 +385234 Gm5376 MGI:MGI:3645898 +385246 Gm5377 MGI:MGI:3649173 +385253 Igkv4-55 MGI:MGI:2686370|IMGT/GENE-DB:IGKV4-55 +385263 Gm1527 MGI:MGI:2686373|Ensembl:ENSMUSG00000074655|Vega:OTTMUSG00000051224 +385277 Igkv4-60 MGI:MGI:3708737|IMGT/GENE-DB:IGKV4-60 +385291 Igkv4-54 MGI:MGI:5009821|IMGT/GENE-DB:IGKV4-54 +385298 Gm5378 MGI:MGI:3779487 +385312 Ssxb10 MGI:MGI:2446779|Ensembl:ENSMUSG00000068219|Vega:OTTMUSG00000016642 +385316 Gm5379 MGI:MGI:3646912 +385317 H2al3 MGI:MGI:1922521|Ensembl:ENSMUSG00000048994|Vega:OTTMUSG00000017465 +385326 Gm5380 MGI:MGI:3643773 +385327 Gm5381 MGI:MGI:3643772 +385328 H2al1n MGI:MGI:3643774|Ensembl:ENSMUSG00000078346|Vega:OTTMUSG00000016908 +385333 Gm5383 MGI:MGI:3646658 +385336 Gm5384 MGI:MGI:3646660 +385338 Ssxa1 MGI:MGI:2446782 +385343 Rhox1 MGI:MGI:3580237|Ensembl:ENSMUSG00000071773|Vega:OTTMUSG00000017122 +385346 Gm5386 MGI:MGI:3644449 +385354 Frmd7 MGI:MGI:2686379|Ensembl:ENSMUSG00000036131|Vega:OTTMUSG00000017472 +385355 Gm5387 MGI:MGI:3647396 +385356 Gm5388 MGI:MGI:3647395 +385362 Gm5389 MGI:MGI:3644211 +385367 Gm5390 MGI:MGI:3644210 +385372 Gm5391 MGI:MGI:3647141 +385377 Pnma5 MGI:MGI:2180566|Ensembl:ENSMUSG00000050424|Vega:OTTMUSG00000017701 +385380 Tex28 MGI:MGI:2686384|Ensembl:ENSMUSG00000062564|Vega:OTTMUSG00000017678 +385383 Xlr5d-ps MGI:MGI:3574110 +385404 Gm5392 MGI:MGI:3642997 +385407 Gm5393 MGI:MGI:3642996 +385417 Gm14926 MGI:MGI:3705617 +385419 Gm5394 MGI:MGI:3646155 +385448 Gm5395 MGI:MGI:3645838 +385454 Gm5396 MGI:MGI:3646589 +385472 Gm5397 MGI:MGI:3645241 +385474 Gm5398 MGI:MGI:3646383 +385493 AU015836 MGI:MGI:2147954|Ensembl:ENSMUSG00000081044|Vega:OTTMUSG00000018005 +385495 Gm5400 MGI:MGI:3645346 +385499 Gm5401 MGI:MGI:3645347 +385500 Gm5402 MGI:MGI:3644522 +385516 Gm14333 MGI:MGI:3649939 +385521 Gm14571 MGI:MGI:3644699 +385523 Gm5403 MGI:MGI:3644700 +385527 Gm14585 MGI:MGI:3709649 +385550 Srsy MGI:MGI:3526567|Ensembl:ENSMUSG00000096819 +385568 Gm20739 MGI:MGI:5434095 +385643 Kng2 MGI:MGI:3027157|Ensembl:ENSMUSG00000060459|Vega:OTTMUSG00000028303 +385658 Nxpe3 MGI:MGI:2686598|Ensembl:ENSMUSG00000075033 +385668 Lca5l MGI:MGI:3041157|Ensembl:ENSMUSG00000045275|Vega:OTTMUSG00000020059 +385674 Zfp174 MGI:MGI:2686600|Ensembl:ENSMUSG00000054939|Vega:OTTMUSG00000036560 +385737 Gm1758 MGI:MGI:2686604 +385748 Gm5404 MGI:MGI:3647383 +385820 Gm5405 MGI:MGI:3643410 +385905 Gm5406 MGI:MGI:3645119 +386061 Gm5407 MGI:MGI:3644612 +386426 Gm15593 MGI:MGI:3783040 +386446 Trav15-1-dv6-1 MGI:MGI:4439369|IMGT/GENE-DB:TRAV15-1/DV6-1 +386450 Trav7-4 MGI:MGI:3649611|IMGT/GENE-DB:TRAV7-4 +386454 Rnf39 MGI:MGI:2156378|Ensembl:ENSMUSG00000036492|Vega:OTTMUSG00000037383 +386463 Cdsn MGI:MGI:3505689|Ensembl:ENSMUSG00000039518|Vega:OTTMUSG00000037244 +386506 Gm5408 MGI:MGI:3647344 +386551 Gm5409 MGI:MGI:3643903 +386611 Rnf133 MGI:MGI:2677436|Ensembl:ENSMUSG00000051956|Vega:OTTMUSG00000022890 +386612 Thoc6 MGI:MGI:2677480|Ensembl:ENSMUSG00000041319|Vega:OTTMUSG00000023716 +386626 Zfp640 MGI:MGI:2678025 +386649 Nsfl1c MGI:MGI:3042273|Ensembl:ENSMUSG00000027455|Vega:OTTMUSG00000015798 +386655 Eid2 MGI:MGI:2681174|Ensembl:ENSMUSG00000046058|Vega:OTTMUSG00000022880 +386750 Slitrk3 MGI:MGI:2679447|Ensembl:ENSMUSG00000048304|Vega:OTTMUSG00000051718 +386753 Dbpht2 MGI:MGI:2679513|Ensembl:ENSMUSG00000029878 +387131 Ssxb9 MGI:MGI:2446778|Ensembl:ENSMUSG00000068218|Vega:OTTMUSG00000016641 +387132 Ssxb2 MGI:MGI:2446771|Ensembl:ENSMUSG00000023165|Vega:OTTMUSG00000016666 +387133 Mir9-1 MGI:MGI:2676911|Ensembl:ENSMUSG00000106493|miRBase:MI0000720 +387134 Mir16-1 MGI:MGI:2676843|Ensembl:ENSMUSG00000092995|miRBase:MI0000565 +387135 Mir18 MGI:MGI:2676844|Ensembl:ENSMUSG00000065403|miRBase:MI0000567 +387136 Mir1a-1 MGI:MGI:2676869|Ensembl:ENSMUSG00000070144|miRBase:MI0000139 +387139 Mir20a MGI:MGI:2676872|Ensembl:ENSMUSG00000065442|miRBase:MI0000568 +387140 Mir21a MGI:MGI:2676885|Ensembl:ENSMUSG00000065455|miRBase:MI0000569 +387141 Mir22 MGI:MGI:2676896|Ensembl:ENSMUSG00000065529|miRBase:MI0000570 +387142 Mir24-1 MGI:MGI:2676899|Ensembl:ENSMUSG00000105904|miRBase:MI0000231 +387143 Mir101a MGI:MGI:2676803|Ensembl:ENSMUSG00000065451|miRBase:MI0000148 +387144 Mir10b MGI:MGI:2676804|Ensembl:ENSMUSG00000065500|miRBase:MI0000221 +387145 Mir126a MGI:MGI:2676811|Ensembl:ENSMUSG00000065540|miRBase:MI0000153 +387146 Mir127 MGI:MGI:2676812|Ensembl:ENSMUSG00000070076|miRBase:MI0000154 +387147 Mir128-1 MGI:MGI:2676813|Ensembl:ENSMUSG00000065520|miRBase:MI0000155 +387148 Mir129 MGI:MGI:2676814 +387149 Mir130a MGI:MGI:2676816|Ensembl:ENSMUSG00000065484|miRBase:MI0000156 +387150 Mir132 MGI:MGI:2676817|Ensembl:ENSMUSG00000065537|miRBase:MI0000158 +387151 Mir133a-1 MGI:MGI:2676818|Ensembl:ENSMUSG00000065399|miRBase:MI0000159 +387152 Mir134 MGI:MGI:2676819|Ensembl:ENSMUSG00000065426|miRBase:MI0000160 +387153 Mir135a-1 MGI:MGI:2676820|Ensembl:ENSMUSG00000065407|miRBase:MI0000161 +387154 Mir136 MGI:MGI:2676821|Ensembl:ENSMUSG00000104858|miRBase:MI0000162 +387155 Mir137 MGI:MGI:2676822|Ensembl:ENSMUSG00000065569|miRBase:MI0000163 +387156 Mir138-1 MGI:MGI:2676823|Ensembl:ENSMUSG00000065414|miRBase:MI0000722 +387157 Mir139 MGI:MGI:2676824|Ensembl:ENSMUSG00000065446|miRBase:MI0000693 +387158 Mir140 MGI:MGI:2676825|Ensembl:ENSMUSG00000065439|miRBase:MI0000165 +387159 Mir141 MGI:MGI:2676826|Ensembl:ENSMUSG00000065474|miRBase:MI0000166 +387160 Mir142 MGI:MGI:2676827|Ensembl:ENSMUSG00000105196|miRBase:MI0000167 +387161 Mir143 MGI:MGI:2676828|Ensembl:ENSMUSG00000065445|miRBase:MI0000257 +387162 Mir144 MGI:MGI:2676829|Ensembl:ENSMUSG00000065401|miRBase:MI0000168 +387163 Mir145a MGI:MGI:2676830|Ensembl:ENSMUSG00000065592|miRBase:MI0000169 +387164 Mir146 MGI:MGI:2676831|Ensembl:ENSMUSG00000065601|miRBase:MI0000170 +387165 Mir147 MGI:MGI:2676832|Ensembl:ENSMUSG00000076309|miRBase:MI0005482 +387166 Mir148a MGI:MGI:2676833|Ensembl:ENSMUSG00000065505|miRBase:MI0000550 +387167 Mir149 MGI:MGI:2676834|Ensembl:ENSMUSG00000065470|miRBase:MI0000171 +387168 Mir150 MGI:MGI:2676835|Ensembl:ENSMUSG00000065495|miRBase:MI0000172 +387169 Mir151 MGI:MGI:2676836|Ensembl:ENSMUSG00000065612|miRBase:MI0000173 +387170 Mir152 MGI:MGI:2676837|Ensembl:ENSMUSG00000065515|miRBase:MI0000174 +387171 Mir153 MGI:MGI:2676838|Ensembl:ENSMUSG00000065538|miRBase:MI0000175 +387172 Mir154 MGI:MGI:2676839|Ensembl:ENSMUSG00000065448|miRBase:MI0000176 +387173 Mir155 MGI:MGI:2676840|Ensembl:ENSMUSG00000065397|miRBase:MI0000177 +387174 Mir15a MGI:MGI:2676841|Ensembl:ENSMUSG00000093007|miRBase:MI0000564 +387175 Mir15b MGI:MGI:2676842|Ensembl:ENSMUSG00000065580|miRBase:MI0000140 +387176 Mir181a-2 MGI:MGI:2676845|Ensembl:ENSMUSG00000065423|miRBase:MI0000223 +387177 Mir182 MGI:MGI:2676846|Ensembl:ENSMUSG00000076361|miRBase:MI0000224 +387178 Mir183 MGI:MGI:2676847|Ensembl:ENSMUSG00000065619|miRBase:MI0000225 +387179 Mir184 MGI:MGI:2676848|Ensembl:ENSMUSG00000065596|miRBase:MI0000226 +387180 Mir185 MGI:MGI:2676849|Ensembl:ENSMUSG00000065464|miRBase:MI0000227 +387181 Mir186 MGI:MGI:2676850|Ensembl:ENSMUSG00000065431|miRBase:MI0000228 +387182 Mir187 MGI:MGI:2676851|Ensembl:ENSMUSG00000065532|miRBase:MI0000229 +387183 Mir188 MGI:MGI:2676852|Ensembl:ENSMUSG00000065398|miRBase:MI0000230 +387185 Mir190a MGI:MGI:2676854|Ensembl:ENSMUSG00000076379|miRBase:MI0000232 +387186 Mir191 MGI:MGI:2676855|Ensembl:ENSMUSG00000105497|miRBase:MI0000233 +387187 Mir192 MGI:MGI:2676856|Ensembl:ENSMUSG00000065523|miRBase:MI0000551 +387188 Mir193a MGI:MGI:2676857|Ensembl:ENSMUSG00000065395|miRBase:MI0000235 +387189 Mir194-1 MGI:MGI:2676858|Ensembl:ENSMUSG00000065581|miRBase:MI0000236 +387190 Mir195a MGI:MGI:2676859|Ensembl:ENSMUSG00000065411|miRBase:MI0000237 +387191 Mir196a-1 MGI:MGI:2676860|Ensembl:ENSMUSG00000065546|miRBase:MI0000552 +387194 Mir199a-1 MGI:MGI:2676863|Ensembl:ENSMUSG00000065547|miRBase:MI0000241 +387195 Mir19b-2 MGI:MGI:2676868|Ensembl:ENSMUSG00000065473|miRBase:MI0000546 +387197 Mir201 MGI:MGI:2676876|Ensembl:ENSMUSG00000065404|miRBase:MI0000244 +387198 Mir202 MGI:MGI:2676877|Ensembl:ENSMUSG00000065502|miRBase:MI0000245 +387199 Mir203 MGI:MGI:2676878|Ensembl:ENSMUSG00000065574|miRBase:MI0000246 +387200 Mir204 MGI:MGI:2676879|Ensembl:ENSMUSG00000065507|miRBase:MI0000247 +387201 Mir205 MGI:MGI:2676880|Ensembl:ENSMUSG00000065533|miRBase:MI0000248 +387202 Mir206 MGI:MGI:2676881|Ensembl:ENSMUSG00000065559|miRBase:MI0000249 +387203 Mir207 MGI:MGI:2676882|Ensembl:ENSMUSG00000065452|miRBase:MI0000250 +387204 Mir208a MGI:MGI:2676883|Ensembl:ENSMUSG00000065432|miRBase:MI0000555 +387206 Mir210 MGI:MGI:2676886|Ensembl:ENSMUSG00000065551|miRBase:MI0000695 +387207 Mir211 MGI:MGI:2676887|Ensembl:ENSMUSG00000065585|miRBase:MI0000708 +387208 Mir212 MGI:MGI:2676888|Ensembl:ENSMUSG00000065590|miRBase:MI0000696 +387210 Mir214 MGI:MGI:2676890|Ensembl:ENSMUSG00000065516|miRBase:MI0000698 +387211 Mir215 MGI:MGI:2676891|Ensembl:ENSMUSG00000065562|miRBase:MI0000974 +387212 Mir216a MGI:MGI:2676892|Ensembl:ENSMUSG00000065539|miRBase:MI0000699 +387213 Mir217 MGI:MGI:2676893|Ensembl:ENSMUSG00000065415|miRBase:MI0000731 +387214 Mir218 MGI:MGI:2676894 +387216 Mir23a MGI:MGI:2676897|Ensembl:ENSMUSG00000065611|miRBase:MI0000571 +387217 Mir23b MGI:MGI:2676898|Ensembl:ENSMUSG00000065599|miRBase:MI0000141 +387218 Mir26a-1 MGI:MGI:2676900|Ensembl:ENSMUSG00000065513|miRBase:MI0000573 +387219 Mir26b MGI:MGI:2676901|Ensembl:ENSMUSG00000065468|miRBase:MI0000575 +387220 Mir27a MGI:MGI:2676902|Ensembl:ENSMUSG00000065444|miRBase:MI0000578 +387221 Mir27b MGI:MGI:2676903|Ensembl:ENSMUSG00000065475|miRBase:MI0000142 +387222 Mir29a MGI:MGI:2676904|Ensembl:ENSMUSG00000065610|miRBase:MI0000576 +387223 Mir29b-1 MGI:MGI:2676905|Ensembl:ENSMUSG00000065604|miRBase:MI0000143 +387224 Mir29c MGI:MGI:2676906|Ensembl:ENSMUSG00000065548|miRBase:MI0000577 +387225 Mir30a MGI:MGI:2676907|Ensembl:ENSMUSG00000065405|miRBase:MI0000144 +387226 Mir30b MGI:MGI:2676908|Ensembl:ENSMUSG00000065476|miRBase:MI0000145 +387227 Mir30c-1 MGI:MGI:2676909|Ensembl:ENSMUSG00000065490|miRBase:MI0000547 +387228 Mir30d MGI:MGI:2676910|Ensembl:ENSMUSG00000065437|miRBase:MI0000549 +387229 Mir99a MGI:MGI:2676912|Ensembl:ENSMUSG00000065530|miRBase:MI0000146 +387230 Mir99b MGI:MGI:2676913|Ensembl:ENSMUSG00000065396|miRBase:MI0000147 +387231 Mir122 MGI:MGI:2676805|Ensembl:ENSMUSG00000065402|miRBase:MI0000256 +387232 Mir122b MGI:MGI:2676806 +387233 Mir124a-1 MGI:MGI:2676807|Ensembl:ENSMUSG00000065597|miRBase:MI0000716 +387234 Mir124b MGI:MGI:2676808 +387235 Mir125a MGI:MGI:2676809|Ensembl:ENSMUSG00000065479|miRBase:MI0000151 +387236 Mir125b-1 MGI:MGI:2676810|Ensembl:ENSMUSG00000093354|miRBase:MI0000725 +387237 Mir129-1 MGI:MGI:2676815|Ensembl:ENSMUSG00000065469|miRBase:MI0000222 +387239 Mir199b MGI:MGI:2676865|Ensembl:ENSMUSG00000092807|miRBase:MI0000714 +387240 Mir199c MGI:MGI:2676866 +387241 Mir199s MGI:MGI:2676867 +387242 Mir200a MGI:MGI:2676874|Ensembl:ENSMUSG00000065400|miRBase:MI0000554 +387243 Mir200b MGI:MGI:2676875|Ensembl:ENSMUSG00000065549|miRBase:MI0000243 +387244 Mirlet7a-1 MGI:MGI:2676793|Ensembl:ENSMUSG00000065421|miRBase:MI0000556 +387245 Mirlet7b MGI:MGI:2676794|Ensembl:ENSMUSG00000065564|miRBase:MI0000558 +387246 Mirlet7c-1 MGI:MGI:2676795|Ensembl:ENSMUSG00000065557|miRBase:MI0000559 +387247 Mirlet7d MGI:MGI:2676796|Ensembl:ENSMUSG00000065453|miRBase:MI0000405 +387248 Mirlet7e MGI:MGI:2676797|Ensembl:ENSMUSG00000105758|miRBase:MI0000561 +387249 Mirlet7g MGI:MGI:2676800|Ensembl:ENSMUSG00000065440|miRBase:MI0000137 +387250 Mirlet7h MGI:MGI:2676801 +387251 Mirlet7i MGI:MGI:2676802|Ensembl:ENSMUSG00000065406|miRBase:MI0000138 +387252 Mirlet7f-1 MGI:MGI:2676798|Ensembl:ENSMUSG00000105621|miRBase:MI0000562 +387253 Mirlet7f-2 MGI:MGI:2676799|Ensembl:ENSMUSG00000065602|miRBase:MI0000563 +387284 Ssxb7 MGI:MGI:2446776 +387285 Hcrtr2 MGI:MGI:2680765|Ensembl:ENSMUSG00000032360|Vega:OTTMUSG00000044825 +387314 Tmtc1 MGI:MGI:3039590|Ensembl:ENSMUSG00000030306|Vega:OTTMUSG00000022507 +387334 Defb50 MGI:MGI:3055870|Ensembl:ENSMUSG00000058568|Vega:OTTMUSG00000019981 +387339 Tas2r102 MGI:MGI:2681171|Ensembl:ENSMUSG00000056901|Vega:OTTMUSG00000056956 +387340 Tas2r104 MGI:MGI:2681185|Ensembl:ENSMUSG00000061977|Vega:OTTMUSG00000056786 +387341 Tas2r106 MGI:MGI:2681203|Ensembl:ENSMUSG00000057754|Vega:OTTMUSG00000056785 +387342 Tas2r107 MGI:MGI:2681207|Ensembl:ENSMUSG00000053389|Vega:OTTMUSG00000056784 +387343 Tas2r109 MGI:MGI:2681214|Ensembl:ENSMUSG00000062528|Vega:OTTMUSG00000056970 +387344 Tas2r110 MGI:MGI:2681216|Ensembl:ENSMUSG00000062952|Vega:OTTMUSG00000056963 +387345 Tas2r113 MGI:MGI:2681217|Ensembl:ENSMUSG00000056926|Vega:OTTMUSG00000057006 +387346 Tas2r114 MGI:MGI:2681218|Ensembl:ENSMUSG00000063478|Vega:OTTMUSG00000056788 +387347 Tas2r118 MGI:MGI:2681247|Ensembl:ENSMUSG00000043865|Vega:OTTMUSG00000037020 +387348 Tas2r120 MGI:MGI:2681256|Ensembl:ENSMUSG00000059382|Vega:OTTMUSG00000056951 +387349 Tas2r121 MGI:MGI:2681259|Ensembl:ENSMUSG00000071150|Vega:OTTMUSG00000056952 +387351 Tas2r124 MGI:MGI:2681267|Ensembl:ENSMUSG00000060412|Vega:OTTMUSG00000056955 +387352 Tas2r125 MGI:MGI:2681269|Ensembl:ENSMUSG00000059410|Vega:OTTMUSG00000056965 +387353 Tas2r126 MGI:MGI:2681273|Ensembl:ENSMUSG00000048284|Vega:OTTMUSG00000057556 +387354 Tas2r129 MGI:MGI:2681276|Ensembl:ENSMUSG00000063762|Vega:OTTMUSG00000056967 +387355 Tas2r130 MGI:MGI:2681278|Ensembl:ENSMUSG00000054497|Vega:OTTMUSG00000056783 +387356 Tas2r131 MGI:MGI:2681280|Ensembl:ENSMUSG00000057699|Vega:OTTMUSG00000056968 +387510 Ifnk MGI:MGI:2683287|Ensembl:ENSMUSG00000042993|Vega:OTTMUSG00000006483 +387511 Tas2r134 MGI:MGI:2681300|Ensembl:ENSMUSG00000056115|Vega:OTTMUSG00000057557 +387512 Tas2r135 MGI:MGI:2681302|Ensembl:ENSMUSG00000056203|Vega:OTTMUSG00000057555 +387513 Tas2r138 MGI:MGI:2681306|Ensembl:ENSMUSG00000058250|Vega:OTTMUSG00000039755 +387514 Tas2r143 MGI:MGI:2681310|Ensembl:ENSMUSG00000046652|Vega:OTTMUSG00000057554 +387515 Tas2r144 MGI:MGI:2681312|Ensembl:ENSMUSG00000051917|Vega:OTTMUSG00000057542 +387516 Tas2r146-ps1 MGI:MGI:2681315 +387517 Tas2r111-ps2 MGI:MGI:2681317 +387518 Tas2r145-ps3 MGI:MGI:2681320 +387519 Tas2r141-ps4 MGI:MGI:2681322 +387520 Tas2r142-ps5 MGI:MGI:2681324 +387524 Znrf2 MGI:MGI:1196246|Ensembl:ENSMUSG00000058446|Vega:OTTMUSG00000023430 +387564 Sval3 MGI:MGI:3047714|Ensembl:ENSMUSG00000062833|Vega:OTTMUSG00000026920 +387565 Cd300c MGI:MGI:3032626|Ensembl:ENSMUSG00000058728|Vega:OTTMUSG00000003601 +387586 Ssxb5 MGI:MGI:2446774|Ensembl:ENSMUSG00000071816|Vega:OTTMUSG00000016718 +387588 Ssxb11 MGI:MGI:2446780 +387589 Ssxb12 MGI:MGI:2446781 +387594 Mthfr-ps1 MGI:MGI:2384077 +387609 Zhx2 MGI:MGI:2683087|Ensembl:ENSMUSG00000071757|Vega:OTTMUSG00000028875 +387616 Tas2r140 MGI:MGI:2681298|Ensembl:ENSMUSG00000071147|Vega:OTTMUSG00000056974 +393082 Mettl7a2 MGI:MGI:3026615|Ensembl:ENSMUSG00000056487|Vega:OTTMUSG00000042219 +394191 BC046401 MGI:MGI:2683561 +394252 Serpinb3d MGI:MGI:2683295|Ensembl:ENSMUSG00000058017|Vega:OTTMUSG00000020997 +394430 Ugt1a10 MGI:MGI:3580642|Ensembl:ENSMUSG00000090165|Vega:OTTMUSG00000020817 +394431 Ugt1a@ - +394432 Ugt1a7c MGI:MGI:3032636|Ensembl:ENSMUSG00000090124|Vega:OTTMUSG00000020819 +394433 Ugt1a5 MGI:MGI:3032634|Ensembl:ENSMUSG00000089943|Vega:OTTMUSG00000020821 +394434 Ugt1a9 MGI:MGI:3576092|Ensembl:ENSMUSG00000090175|Vega:OTTMUSG00000020809 +394435 Ugt1a6b MGI:MGI:3580629|Ensembl:ENSMUSG00000090145|Vega:OTTMUSG00000020822 +394436 Ugt1a1 MGI:MGI:98898|Ensembl:ENSMUSG00000089960|Vega:OTTMUSG00000020815 +396184 Flrt1 MGI:MGI:3026647|Ensembl:ENSMUSG00000047787 +399101 Snhg3 MGI:MGI:2684817|Ensembl:ENSMUSG00000085241 +399510 Map4k5 MGI:MGI:1925503|Ensembl:ENSMUSG00000034761|Vega:OTTMUSG00000017571 +399548 Scn4b MGI:MGI:2687406|Ensembl:ENSMUSG00000046480|Vega:OTTMUSG00000016701 +399549 H2-M10.6 MGI:MGI:2687364|Ensembl:ENSMUSG00000037130|Vega:OTTMUSG00000037373 +399558 Flrt2 MGI:MGI:3603594|Ensembl:ENSMUSG00000047414|Vega:OTTMUSG00000017572 +399566 Btbd6 MGI:MGI:3026623|Ensembl:ENSMUSG00000002803 +399568 BC052040 MGI:MGI:3026886|Ensembl:ENSMUSG00000040282|Vega:OTTMUSG00000015218 +399570 Kank4os MGI:MGI:3026921|Ensembl:ENSMUSG00000085843 +399572 E430010N07Rik MGI:MGI:3026932 +399573 1110065F06Rik MGI:MGI:3026937 +399574 D630050G16Rik MGI:MGI:3026938 +399575 D930021H04Rik MGI:MGI:3026942 +399577 B230204D01Rik MGI:MGI:3026947 +399578 8030447M02Rik MGI:MGI:3026949 +399579 6720462K09Rik MGI:MGI:3026951 +399580 C130051G18Rik MGI:MGI:3026958 +399581 C130057M05Rik MGI:MGI:3026960 +399582 C730045M19Rik MGI:MGI:3026961 +399583 E330034L11Rik MGI:MGI:3026962 +399587 6430502G17Rik MGI:MGI:3026972 +399590 C230011H18Rik MGI:MGI:3026986 +399591 Tmsb15l MGI:MGI:3026988|Ensembl:ENSMUSG00000072955|Ensembl:ENSMUSG00000089996|Vega:OTTMUSG00000018827 +399592 8430406M14Rik MGI:MGI:3026990 +399593 8030497I03Rik MGI:MGI:3026991 +399594 D430013B06Rik MGI:MGI:3026994 +399597 B130011D17Rik MGI:MGI:3026999 +399599 Ccdc87 MGI:MGI:3026882|Ensembl:ENSMUSG00000067872 +399600 7030407E18Rik MGI:MGI:3026917 +399601 D830039D19Rik MGI:MGI:3026919 +399602 9930024M15Rik MGI:MGI:3026920 +399603 Fam84b MGI:MGI:3026924|Ensembl:ENSMUSG00000072568|Vega:OTTMUSG00000047161 +399604 C530014P21Rik MGI:MGI:3026926 +399605 D330045E12Rik MGI:MGI:3026927 +399606 D230007G03Rik MGI:MGI:3026929 +399607 D230019N24Rik MGI:MGI:3026933 +399608 9430088F21Rik MGI:MGI:3026934 +399609 C130046K22Rik MGI:MGI:3026935 +399611 A230091C14Rik MGI:MGI:3026940 +399612 9630010G10Rik MGI:MGI:3026941 +399614 C130009A20Rik MGI:MGI:3026948 +399616 A130078K24Rik MGI:MGI:3026952 +399617 A130019P10Rik MGI:MGI:3026953 +399619 A930027P06Rik MGI:MGI:3026956 +399621 A630024P14Rik MGI:MGI:3026964 +399623 5930433N17Rik MGI:MGI:3026967 +399625 2410003I16Rik MGI:MGI:3026974 +399626 C330024C12Rik MGI:MGI:3026976 +399627 D030007L05Rik MGI:MGI:3026977 +399629 9530029O12Rik MGI:MGI:3026981 +399631 D130009B15Rik MGI:MGI:3026985 +399632 A330001L22Rik MGI:MGI:3026987 +399633 A630014C17Rik MGI:MGI:3026989 +399635 D230044B12Rik MGI:MGI:3026993 +399636 9530001J02Rik MGI:MGI:3026995 +399637 C130079B09Rik MGI:MGI:3027000 +399638 A030001D16Rik MGI:MGI:3027004 +399639 C530038A18Rik MGI:MGI:3027006 +399640 A1300008O04Rik MGI:MGI:3026923 +399641 A7300091P13Rik MGI:MGI:3026955 +399673 Tdpoz2 MGI:MGI:3027902|Ensembl:ENSMUSG00000103362|Vega:OTTMUSG00000049965 +399674 Tdpoz3 MGI:MGI:3027903|Ensembl:ENSMUSG00000058005|Vega:OTTMUSG00000051998 +399675 Tdpoz4 MGI:MGI:3027904|Ensembl:ENSMUSG00000060256|Vega:OTTMUSG00000051997 +399676 Tdpoz5 MGI:MGI:3027905|Ensembl:ENSMUSG00000094163|Vega:OTTMUSG00000049968 +402722 E030016H06Rik MGI:MGI:3028027 +402723 E130104P22Rik MGI:MGI:3028028 +402724 A330106F07Rik MGI:MGI:3028029 +402725 C530045E16Rik MGI:MGI:3028030 +402726 A630028G03Rik MGI:MGI:3028031 +402727 A730009L09Rik MGI:MGI:3028032 +402728 Pax6os1 MGI:MGI:3028033|Ensembl:ENSMUSG00000086029 +402729 9330184L24Rik MGI:MGI:3028034 +402730 Foxo6os MGI:MGI:3028036|Ensembl:ENSMUSG00000084929 +402731 2900046D03Rik MGI:MGI:3028037 +402732 A030012G06Rik MGI:MGI:3028038 +402733 A930009L07Rik MGI:MGI:3028039 +402734 C730036E19Rik MGI:MGI:3028040 +402735 B230114P17Rik MGI:MGI:3028041 +402737 A130014A01Rik MGI:MGI:3028043 +402738 B230308H17Rik MGI:MGI:3028044 +402740 C030010F05Rik MGI:MGI:3028046 +402741 C030004N09Rik MGI:MGI:3028047 +402742 C130013N14Rik MGI:MGI:3028048 +402743 C130063K03Rik MGI:MGI:3028049 +402744 C130076G22Rik MGI:MGI:3028050 +402745 E430022E14Rik MGI:MGI:3028052 +402746 A230054M22Rik MGI:MGI:3028053 +402747 D630004N19Rik MGI:MGI:3028054 +402749 B430316J06Rik MGI:MGI:3028056 +402750 C130057G02Rik MGI:MGI:3028057 +402751 C430019N01Rik MGI:MGI:3028058 +402752 C130068B02Rik MGI:MGI:3028059 +402753 D630033A02Rik MGI:MGI:3028060 +402754 5930427L02Rik MGI:MGI:3028061 +402755 6030487A22Rik MGI:MGI:3028062 +402756 6030495B02Rik MGI:MGI:3028063 +402757 9830166K06Rik MGI:MGI:3028064 +402758 A330074H02Rik MGI:MGI:3028065 +402759 A330087D11Rik MGI:MGI:3028066 +402760 A430050A11Rik MGI:MGI:3028067 +402761 A530064N14Rik MGI:MGI:3028068 +402762 A630039O03Rik MGI:MGI:3028069 +402763 A630073K07Rik MGI:MGI:3028070 +402764 6030403N03Rik MGI:MGI:3028071 +402765 6030422H21Rik MGI:MGI:3028072 +402766 7030407A21Rik MGI:MGI:3028073 +402767 A830052D11Rik MGI:MGI:3028074|Ensembl:ENSMUSG00000097413 +402768 B230209G03Rik MGI:MGI:3028076 +402769 C130033p17rik - +402770 C130083A15Rik MGI:MGI:3028079 +402771 C130090I23Rik MGI:MGI:3028080 +402772 C130098B18Rik MGI:MGI:3028081 +402773 D030018L15Rik MGI:MGI:3028082|Ensembl:ENSMUSG00000078925 +402774 D030025E07Rik MGI:MGI:3028083|Ensembl:ENSMUSG00000105816 +402775 D130095D21Rik MGI:MGI:3028084 +403088 Tcaf3 MGI:MGI:3042585|Ensembl:ENSMUSG00000018656|Vega:OTTMUSG00000026941 +403171 Banf2 MGI:MGI:2684961|Ensembl:ENSMUSG00000037307|Vega:OTTMUSG00000003371 +403172 Defb21 MGI:MGI:2684967|Ensembl:ENSMUSG00000056544|Vega:OTTMUSG00000015840 +403174 Msantd1 MGI:MGI:2684990|Ensembl:ENSMUSG00000051246|Vega:OTTMUSG00000055723 +403175 Tigd4 MGI:MGI:2685264|Ensembl:ENSMUSG00000047819|Vega:OTTMUSG00000051605 +403178 Plcxd1 MGI:MGI:2685422|Ensembl:ENSMUSG00000064247|Vega:OTTMUSG00000026195 +403180 Ccdc121 MGI:MGI:2685601|Ensembl:ENSMUSG00000050625|Vega:OTTMUSG00000044368 +403183 Mettl21e MGI:MGI:2685837|Ensembl:ENSMUSG00000046828|Vega:OTTMUSG00000026594 +403185 4932443I19Rik MGI:MGI:2685952|Ensembl:ENSMUSG00000090336 +403187 Opa3 MGI:MGI:2686271|Ensembl:ENSMUSG00000052214|Vega:OTTMUSG00000031701 +403200 4930504O13Rik MGI:MGI:2685370|Ensembl:ENSMUSG00000052642|Vega:OTTMUSG00000005738 +403201 5330416C01Rik MGI:MGI:2685378 +403202 A430093F15Rik MGI:MGI:2685520|Ensembl:ENSMUSG00000067577 +403205 Agr3 MGI:MGI:2685734|Ensembl:ENSMUSG00000036231|Vega:OTTMUSG00000027575 +403342 C130015C19 - +403343 130004C03 - +403344 C230006B20 - +403345 BC037438 MGI:MGI:3029293 +403346 A730062M13Rik MGI:MGI:3029302 +403347 F830014O18Rik MGI:MGI:3029303 +403348 D130084N16Rik MGI:MGI:3029304 +403350 F830003O12Rik MGI:MGI:3029301 +403351 D430018B14Rik MGI:MGI:3029305 +403355 Klra24 MGI:MGI:3029294 +403395 Clec3a MGI:MGI:2685642|Ensembl:ENSMUSG00000008874|Vega:OTTMUSG00000028626 +404194 Gfral MGI:MGI:3607786|Ensembl:ENSMUSG00000059383|Vega:OTTMUSG00000044824 +404195 Cyp2c54 MGI:MGI:3642960|Ensembl:ENSMUSG00000067225 +404212 Pisrt1 MGI:MGI:3028611 +404222 Olfr231 MGI:MGI:3030065|Ensembl:ENSMUSG00000046486|Vega:OTTMUSG00000050214 +404235 Mrgpra5 MGI:MGI:3033102 +404236 Mrgpra7 MGI:MGI:3033109 +404237 Mrgpra8 MGI:MGI:3033111 +404238 Mrgprb3 MGI:MGI:3033117|Ensembl:ENSMUSG00000070546|Vega:OTTMUSG00000046631 +404239 Mrgprb5 MGI:MGI:3033121|Ensembl:ENSMUSG00000070551|Vega:OTTMUSG00000046605 +404240 Mrgprb8 MGI:MGI:3033134|Ensembl:ENSMUSG00000050870|Vega:OTTMUSG00000046624 +404242 Mrgprx1 MGI:MGI:3033139|Ensembl:ENSMUSG00000070552|Vega:OTTMUSG00000046583 +404243 Mrgpra10 MGI:MGI:3033150 +404244 Mrgpra11 MGI:MGI:3033153 +404245 Mrgpra12 MGI:MGI:3033158 +404246 Mrgpra13 MGI:MGI:3033161 +404247 Mrgpra14 MGI:MGI:3033168 +404248 Mrgpra15 MGI:MGI:3033171 +404249 Mrgpra16 MGI:MGI:3033174 +404250 Mrgpra19 MGI:MGI:3033178 +404252 Mrgprb7-ps MGI:MGI:3033123 +404253 Mrgprb9-ps MGI:MGI:3033133 +404254 Mrgprc2-ps MGI:MGI:3033137 +404255 Mrgprc7-ps MGI:MGI:3033141 +404256 Mrgprc3-ps MGI:MGI:3033196 +404257 Mrgprc4-ps MGI:MGI:3033197 +404262 Mrgpra18-ps MGI:MGI:3033177 +404264 Mrgprb12-ps MGI:MGI:3033192 +404284 Vmn1r59 MGI:MGI:3033479|Ensembl:ENSMUSG00000074401|Vega:OTTMUSG00000037742 +404285 Vmn1r64 MGI:MGI:3033480|Ensembl:ENSMUSG00000058399|Vega:OTTMUSG00000037787 +404286 Vmn1r179 MGI:MGI:3033486|Ensembl:ENSMUSG00000046924|Vega:OTTMUSG00000038013 +404287 V1rd19 MGI:MGI:3033488|Ensembl:ENSMUSG00000092456|Vega:OTTMUSG00000038016 +404288 V1rd18 MGI:MGI:3033487 +404289 Vmn1r181 MGI:MGI:3033489|Ensembl:ENSMUSG00000097425|Vega:OTTMUSG00000038015 +404290 Vmn1r93 MGI:MGI:3033490|Ensembl:ENSMUSG00000096164|Vega:OTTMUSG00000038185 +404291 Vmn1r174 MGI:MGI:3033491|Ensembl:ENSMUSG00000090411|Vega:OTTMUSG00000038007 +404307 Olfr100 MGI:MGI:2177483 +404308 Olfr118 MGI:MGI:2177501|Ensembl:ENSMUSG00000080990|Vega:OTTMUSG00000037468 +404309 Olfr192 MGI:MGI:3030026|Ensembl:ENSMUSG00000108464|Vega:OTTMUSG00000058845 +404310 Olfr199 MGI:MGI:3030033|Ensembl:ENSMUSG00000074996|Vega:OTTMUSG00000059127 +404311 Olfr209 MGI:MGI:3030043|Ensembl:ENSMUSG00000095706|Vega:OTTMUSG00000059134 +404312 Olfr250 MGI:MGI:3030084|Ensembl:ENSMUSG00000049864|Vega:OTTMUSG00000062118 +404313 Olfr251 MGI:MGI:3030085|Ensembl:ENSMUSG00000096757|Vega:OTTMUSG00000062117 +404314 Olfr257 MGI:MGI:3030091 +404315 Olfr372 MGI:MGI:3030206|Ensembl:ENSMUSG00000069998|Vega:OTTMUSG00000061130 +404316 Olfr403 MGI:MGI:3030237|Ensembl:ENSMUSG00000070378|Vega:OTTMUSG00000006175 +404317 Olfr592 MGI:MGI:3030426|Ensembl:ENSMUSG00000073956|Vega:OTTMUSG00000019055 +404318 Olfr681 MGI:MGI:3030515|Ensembl:ENSMUSG00000095248|Vega:OTTMUSG00000060647 +404319 Olfr750 MGI:MGI:3030584|Ensembl:ENSMUSG00000035932|Vega:OTTMUSG00000058564 +404321 Olfr776 MGI:MGI:3030610|Ensembl:ENSMUSG00000095483|Vega:OTTMUSG00000056557 +404322 Olfr924 MGI:MGI:3030758|Ensembl:ENSMUSG00000062103|Vega:OTTMUSG00000062205 +404323 Olfr1040 MGI:MGI:3030874|Ensembl:ENSMUSG00000075203|Vega:OTTMUSG00000013656 +404324 Olfr1051 MGI:MGI:3030885|Ensembl:ENSMUSG00000075193|Vega:OTTMUSG00000013532 +404325 Olfr1057 MGI:MGI:3030891|Ensembl:ENSMUSG00000075187|Vega:OTTMUSG00000013567 +404326 Olfr1083-ps MGI:MGI:3030917 +404327 Olfr1113 MGI:MGI:3030947|Ensembl:ENSMUSG00000070857|Vega:OTTMUSG00000013777 +404328 Olfr1118 MGI:MGI:3030952|Ensembl:ENSMUSG00000083706|Vega:OTTMUSG00000013773 +404329 Olfr1173 MGI:MGI:3031007|Ensembl:ENSMUSG00000075132|Vega:OTTMUSG00000013942 +404330 Olfr1198 MGI:MGI:3031032|Ensembl:ENSMUSG00000075117|Vega:OTTMUSG00000014000 +404331 Olfr1252 MGI:MGI:3031086|Ensembl:ENSMUSG00000110819|Vega:OTTMUSG00000014169 +404335 Olfr1535 MGI:MGI:3031369|Ensembl:ENSMUSG00000054890|Vega:OTTMUSG00000000424 +404336 Olfr1380 MGI:MGI:3031214|Ensembl:ENSMUSG00000107645|Vega:OTTMUSG00000005560 +404337 Olfr1383 MGI:MGI:3031217|Ensembl:ENSMUSG00000107417|Vega:OTTMUSG00000005557 +404339 Olfr1480 MGI:MGI:3031314|Ensembl:ENSMUSG00000095484|Vega:OTTMUSG00000059530 +404343 Olfr182-ps1 MGI:MGI:3030016 +404344 Olfr185-ps1 MGI:MGI:3030019 +404345 Olfr188-ps1 MGI:MGI:3030022 +404346 Olfr322 MGI:MGI:3030156|Ensembl:ENSMUSG00000063549|Vega:OTTMUSG00000005755 +404355 Olfr238 MGI:MGI:3030072 +404356 Olfr240-ps1 MGI:MGI:3030074 +404357 Olfr241-ps1 MGI:MGI:3030075 +404360 Olfr246-ps1 MGI:MGI:3030080 +404362 Olfr1304-ps1 MGI:MGI:3031138 +404363 Olfr254-ps1 MGI:MGI:3030088 +404364 Olfr256 MGI:MGI:3030090 +404365 Olfr260-ps1 MGI:MGI:3030094 +404366 Olfr626-ps1 MGI:MGI:3030460 +404368 Olfr274-ps1 MGI:MGI:3030108 +404371 Olfr278-ps1 MGI:MGI:3030112 +404373 Olfr280-ps1 MGI:MGI:3030114 +404374 Olfr289-ps1 MGI:MGI:3030123 +404375 Olfr296-ps1 MGI:MGI:3030130 +404376 Olfr302 MGI:MGI:3030136 +404377 Olfr306-ps1 MGI:MGI:3030140 +404379 Olfr343-ps1 MGI:MGI:3030177 +404380 Olfr363-ps MGI:MGI:3030197 +404381 Olfr369-ps1 MGI:MGI:3030203 +404384 Olfr258-ps1 MGI:MGI:3030092 +404386 Olfr428-ps1 MGI:MGI:3030262 +404393 Olfr468-ps1 MGI:MGI:3030302 +404395 Olfr475-ps1 MGI:MGI:3030309 +404396 Olfr499-ps1 MGI:MGI:3030333 +404397 Olfr511-ps1 MGI:MGI:3030345 +404398 Olfr515-ps1 MGI:MGI:3030349 +404399 Olfr1191-ps1 MGI:MGI:3031025 +404400 Olfr528-ps1 MGI:MGI:3030362 +404401 Olfr529-ps1 MGI:MGI:3030363 +404402 Olfr534-ps1 MGI:MGI:3030368 +404405 Olfr546-ps1 MGI:MGI:3030380 +404406 Olfr581-ps1 MGI:MGI:3030415 +404407 Olfr587-ps1 MGI:MGI:3030421 +404413 Olfr662-ps1 MGI:MGI:3030496 +404416 Olfr696-ps1 MGI:MGI:3030530 +404417 Olfr712-ps1 MGI:MGI:3030546 +404418 Olfr719-ps MGI:MGI:3030553 +404422 Olfr758-ps1 MGI:MGI:3030592 +404423 Olfr760-ps1 MGI:MGI:3030594 +404424 Olfr762-ps1 MGI:MGI:3030596 +404426 Olfr778-ps1 MGI:MGI:3030612 +404427 Olfr793-ps1 MGI:MGI:3030627 +404431 Olfr831-ps1 MGI:MGI:3030665 +404435 Olfr848-ps1 MGI:MGI:3030682 +404436 Olfr852-ps1 MGI:MGI:3030686 +404437 Olfr861-ps1 MGI:MGI:3030695 +404438 Olfr865-ps1 MGI:MGI:3030699 +404440 Olfr880-ps1 MGI:MGI:3030714 +404441 Olfr1543-ps1 MGI:MGI:3031377 +404443 Olfr928-ps1 MGI:MGI:3030762 +404446 Olfr932-ps1 MGI:MGI:3030766 +404447 Olfr939-ps1 MGI:MGI:3030773 +404449 Olfr942-ps1 MGI:MGI:3030776 +404451 Olfr950-ps1 MGI:MGI:3030784 +404452 Olfr953-ps1 MGI:MGI:3030787 +404455 Olfr991-ps1 MGI:MGI:3030825 +404460 Olfr1041-ps1 MGI:MGI:3030875 +404461 Olfr1050-ps1 MGI:MGI:3030884 +404462 Olfr1059-ps1 MGI:MGI:3030893 +404463 Olfr1064-ps1 MGI:MGI:3030898 +404464 Olfr1067-ps1 MGI:MGI:3030901 +404465 Olfr1069-ps1 MGI:MGI:3030903 +404466 Olfr1070-ps1 MGI:MGI:3030904 +404467 Olfr1071 MGI:MGI:3030905 +404468 Olfr1072-ps1 MGI:MGI:3030906 +404469 Olfr1074-ps1 MGI:MGI:3030908 +404470 Olfr1075-ps1 MGI:MGI:3030909 +404471 Olfr1078-ps1 MGI:MGI:3030912 +404472 Olfr1081-ps1 MGI:MGI:3030915 +404473 Olfr1082 MGI:MGI:3030916|Ensembl:ENSMUSG00000111689|Vega:OTTMUSG00000013633 +404474 Olfr1088-ps1 MGI:MGI:3030922 +404475 Olfr1091-ps1 MGI:MGI:3030925 +404478 Olfr1114-ps1 MGI:MGI:3030948 +404482 Olfr1169-ps1 MGI:MGI:3031003 +404483 Olfr1172-ps1 MGI:MGI:3031006 +404484 Olfr1187-ps1 MGI:MGI:3031021 +404488 Olfr1210-ps1 MGI:MGI:3031044 +404489 Olfr1227-ps1 MGI:MGI:3031061 +404490 Olfr1235-ps1 MGI:MGI:3031069 +404492 Olfr1237-ps1 MGI:MGI:3031071 +404493 Olfr1244-ps1 MGI:MGI:3031078 +404494 Olfr1266-ps1 MGI:MGI:3031100 +404495 Olfr1292-ps1 MGI:MGI:3031126 +404497 Olfr1315-ps1 MGI:MGI:3031149 +404499 Olfr1327-ps1 MGI:MGI:3031161 +404504 Olfr1369-ps1 MGI:MGI:3031203 +404506 Olfr1379-ps1 MGI:MGI:3031213 +404507 Olfr1398-ps1 MGI:MGI:3031232 +404508 Olfr1399-ps1 MGI:MGI:3031233 +404510 Olfr1401-ps1 MGI:MGI:3031235 +404514 Olfr1421-ps1 MGI:MGI:3031255 +404515 Olfr1455-ps1 MGI:MGI:3031289 +404516 Olfr1456-ps1 MGI:MGI:3031290 +404517 Olfr1476-ps1 MGI:MGI:3031310 +404518 Olfr1478-ps1 MGI:MGI:3031312 +404519 Olfr1479-ps1 MGI:MGI:3031313 +404520 Olfr1481-ps1 MGI:MGI:3031315 +404521 Olfr1482-ps1 MGI:MGI:3031316 +404522 Olfr1483-ps1 MGI:MGI:3031317 +404523 Olfr1485-ps1 MGI:MGI:3031319 +404524 Olfr1486-ps1 MGI:MGI:3031320 +404526 Olfr1492-ps1 MGI:MGI:3031326 +404527 Olfr1503-ps1 MGI:MGI:3031337 +404545 Ano7 MGI:MGI:3052714|Ensembl:ENSMUSG00000034107|Vega:OTTMUSG00000048653 +404549 Ifna14 MGI:MGI:3641425|Ensembl:ENSMUSG00000095896|Vega:OTTMUSG00000007662 +404554 AL024386 MGI:MGI:3034255 +404555 AL118333 MGI:MGI:3034282 +404556 AL024322 MGI:MGI:3034387 +404557 AL024321 MGI:MGI:3034388 +404558 AL118003 MGI:MGI:3034476 +404559 AL118225 MGI:MGI:3034555 +404562 AL118183 MGI:MGI:3034684 +404564 AL118389 MGI:MGI:3034727 +404565 AL118125 MGI:MGI:3034732 +404566 AL024446 MGI:MGI:3034846 +404567 AL118302 MGI:MGI:3034936 +404570 AL118186 MGI:MGI:3034968 +404571 AL118313 MGI:MGI:3035038 +404572 AL117946 MGI:MGI:3035070 +404573 AL118014 MGI:MGI:3035175 +404574 AL118036 MGI:MGI:3035208 +404575 AL118134 MGI:MGI:3035371 +404576 AL118485 MGI:MGI:3034188 +404577 AL035025 MGI:MGI:3034245 +404578 AL118440 MGI:MGI:3034280 +404579 AL118337 MGI:MGI:3034281 +404580 AL117821 MGI:MGI:3034336 +404584 AL117934 MGI:MGI:3034556 +404585 AL117938 MGI:MGI:3034559 +404586 AL024230 MGI:MGI:3034662 +404587 AL117810 MGI:MGI:3034789 +404588 AL117801 MGI:MGI:3034839 +404591 AL117728 MGI:MGI:3034980 +404592 AL117703 MGI:MGI:3035029 +404594 AL118430 MGI:MGI:3035116 +404595 AL118294 MGI:MGI:3035123 +404634 H2afy2 MGI:MGI:3037658|Ensembl:ENSMUSG00000020086|Vega:OTTMUSG00000034121 +404705 Prkcz2 MGI:MGI:3029152 +404710 Iqgap3 MGI:MGI:3028642|Ensembl:ENSMUSG00000028068|Vega:OTTMUSG00000051871 +404711 Ighg2c MGI:MGI:2686979|IMGT/GENE-DB:IGHG2C +404736 Iglc4 MGI:MGI:3642936|IMGT/GENE-DB:IGLC4 +404737 Iglj1 MGI:MGI:5009822|IMGT/GENE-DB:IGLJ1 +404739 Iglj2 MGI:MGI:5293409|IMGT/GENE-DB:IGLJ2 +404740 Iglj3 MGI:MGI:5293407|IMGT/GENE-DB:IGLJ3 +404741 Iglj3p MGI:MGI:3645901|IMGT/GENE-DB:IGLJ3P +404742 Iglj4 MGI:MGI:3645510|IMGT/GENE-DB:IGLJ4 +404743 Iglv3 MGI:MGI:3645509|IMGT/GENE-DB:IGLV3 +406175 Olfr242 MGI:MGI:3030076 +406176 Olfr151 MGI:MGI:2661338|Ensembl:ENSMUSG00000110526|Vega:OTTMUSG00000061696 +406186 Olfr142 MGI:MGI:2177525|Ensembl:ENSMUSG00000075063|Vega:OTTMUSG00000014222 +406209 4930524O07Rik MGI:MGI:1915514 +406217 Bex4 MGI:MGI:3606746|Ensembl:ENSMUSG00000047844|Vega:OTTMUSG00000018774 +406218 Panx2 MGI:MGI:1890615|Ensembl:ENSMUSG00000058441|Vega:OTTMUSG00000033329 +406219 Krt87 MGI:MGI:3665486|Ensembl:ENSMUSG00000047641 +406220 Krt77 MGI:MGI:3588209|Ensembl:ENSMUSG00000067594|Vega:OTTMUSG00000028002 +406221 Krt40 MGI:MGI:3629968|Ensembl:ENSMUSG00000059169|Vega:OTTMUSG00000004986 +406222 Krt74 MGI:MGI:3629975|Ensembl:ENSMUSG00000067596 +406223 Gm5414 MGI:MGI:3646939|Ensembl:ENSMUSG00000064232 +407243 Tmem189 MGI:MGI:2142624|Ensembl:ENSMUSG00000090213|Vega:OTTMUSG00000001145 +407785 Ndufs6 MGI:MGI:107932|Ensembl:ENSMUSG00000021606|Vega:OTTMUSG00000030547 +407786 Taf9b MGI:MGI:3039562|Ensembl:ENSMUSG00000047242|Vega:OTTMUSG00000018278 +407788 BC051142 MGI:MGI:3039565|Ensembl:ENSMUSG00000057246|Vega:OTTMUSG00000020171 +407789 BC048644 MGI:MGI:3039566 +407790 Ndufa4l2 MGI:MGI:3039567|Ensembl:ENSMUSG00000040280 +407791 BC049739 MGI:MGI:3039568 +407793 BC039966 MGI:MGI:3039570 +407795 BC030870 MGI:MGI:3039572|Ensembl:ENSMUSG00000074300|Vega:OTTMUSG00000046325 +407797 BC030308 MGI:MGI:3039575 +407799 BC049285 MGI:MGI:3039577 +407800 Ecm2 MGI:MGI:3039578|Ensembl:ENSMUSG00000043631 +407802 BC028789 MGI:MGI:3039584 +407803 BC051226 MGI:MGI:3039585|Ensembl:ENSMUSG00000092564 +407804 BC051077 MGI:MGI:3039587 +407808 BC050972 MGI:MGI:3039596 +407809 BC055402 MGI:MGI:3039597|Ensembl:ENSMUSG00000101429 +407810 BC046251 MGI:MGI:3039598|Ensembl:ENSMUSG00000086662 +407811 BC060293 MGI:MGI:3039599 +407812 Zfp941 MGI:MGI:3039601|Ensembl:ENSMUSG00000060314|Vega:OTTMUSG00000022510 +407813 BC059841 MGI:MGI:3039604 +407814 BC053393 MGI:MGI:3039605|Ensembl:ENSMUSG00000046974|Vega:OTTMUSG00000005501 +407815 BC049987 MGI:MGI:3039606 +407816 BC023202 MGI:MGI:3039610 +407817 BC059050 MGI:MGI:3039611 +407818 BC055308 MGI:MGI:3039612 +407819 BC031181 MGI:MGI:3039614|Ensembl:ENSMUSG00000036299 +407821 Znrf3 MGI:MGI:3039616|Ensembl:ENSMUSG00000041961|Vega:OTTMUSG00000005083 +407823 Baz2b MGI:MGI:2442782|Ensembl:ENSMUSG00000026987|Vega:OTTMUSG00000012818 +407824 BC020402 MGI:MGI:3039621 +407827 BC058420 MGI:MGI:3039631 +407828 BC023969 MGI:MGI:3039632 +407830 BC010981 MGI:MGI:3039634 +407831 Tmem204 MGI:MGI:3039635|Ensembl:ENSMUSG00000024168|Vega:OTTMUSG00000024887 +407833 BC028454 MGI:MGI:3039639 +407834 BC049688 MGI:MGI:3039640 +408022 Primpol MGI:MGI:3603756|Ensembl:ENSMUSG00000038225|Vega:OTTMUSG00000030980 +408028 Arhgap20os MGI:MGI:3027124|Ensembl:ENSMUSG00000074354 +408056 BC038331 MGI:MGI:3040675 +408057 BC039771 MGI:MGI:3040676|Ensembl:ENSMUSG00000087594 +408058 BC048507 MGI:MGI:3040680|Ensembl:ENSMUSG00000064063 +408059 BC049352 MGI:MGI:3040681|Ensembl:ENSMUSG00000091996|Vega:OTTMUSG00000036046 +408060 BC049692 MGI:MGI:3040682 +408061 BC051408 MGI:MGI:3040685 +408062 Zfp873 MGI:MGI:3040689|Ensembl:ENSMUSG00000061371|Vega:OTTMUSG00000060211 +408063 BC062258 MGI:MGI:3040690 +408064 BC064078 MGI:MGI:3040692 +408065 Zfp456 MGI:MGI:3040694|Ensembl:ENSMUSG00000078995|Vega:OTTMUSG00000036842 +408066 BC067074 MGI:MGI:3040697|Ensembl:ENSMUSG00000021763|Vega:OTTMUSG00000033651 +408067 Zfp874b MGI:MGI:3040702|Ensembl:ENSMUSG00000059839|Vega:OTTMUSG00000042795 +408068 Zfp738 MGI:MGI:3040706|Ensembl:ENSMUSG00000048280|Vega:OTTMUSG00000032933 +408069 C330013J06Rik MGI:MGI:3040710 +408070 B930036G03Rik MGI:MGI:3040798 +408071 D6Wum42 MGI:MGI:3040631 +408072 D6Wum40 MGI:MGI:3040632 +408073 D6Wum27 MGI:MGI:3040634 +408074 D6Wum35 MGI:MGI:3040635 +408075 D6Wum30 MGI:MGI:3040636 +408076 D6Wum34 MGI:MGI:3040638 +408077 D6Wum33 MGI:MGI:3040639 +408078 D6Wum25 MGI:MGI:3040641 +408079 D6Wum31 MGI:MGI:3040642 +408080 D6Wum21 MGI:MGI:3040643 +408081 D6Wum10.1 MGI:MGI:3040633 +408083 Psl4 MGI:MGI:2664119 +408189 Gm14129 MGI:MGI:3651572 +408190 Wfdc13 MGI:MGI:3582777|Ensembl:ENSMUSG00000067704|Vega:OTTMUSG00000016291 +408191 Gm5415 MGI:MGI:3644687|Ensembl:ENSMUSG00000091318|Vega:OTTMUSG00000048930 +408192 Gm9839 MGI:MGI:3641910 +408193 Otud6a MGI:MGI:3644685|Ensembl:ENSMUSG00000051582|Vega:OTTMUSG00000018242 +408196 Gm5416 MGI:MGI:3644688|Ensembl:ENSMUSG00000094733|Vega:OTTMUSG00000028578 +408198 Spink7 MGI:MGI:3644691|Ensembl:ENSMUSG00000060201 +408254 A630019I02Rik MGI:MGI:5439422 +414066 BC037032 MGI:MGI:3040924 +414067 AY512915 MGI:MGI:3041245|Ensembl:ENSMUSG00000068180 +414068 Bach2os MGI:MGI:3041246|Ensembl:ENSMUSG00000086150 +414069 BC024978 MGI:MGI:3041247|Ensembl:ENSMUSG00000078786|Vega:OTTMUSG00000023936 +414070 BC026600 MGI:MGI:3041248 +414071 BC028471 MGI:MGI:3041249 +414072 BC031361 MGI:MGI:3041250 +414073 BC040756 MGI:MGI:3041251 +414075 BC049265 MGI:MGI:3041253 +414076 BC051537 MGI:MGI:3041255|Ensembl:ENSMUSG00000098197 +414077 Wdr83os MGI:MGI:3041257|Ensembl:ENSMUSG00000059355|Vega:OTTMUSG00000022576 +414078 A430018G15Rik MGI:MGI:3040796 +414079 4930405O22Rik MGI:MGI:3041158|Ensembl:ENSMUSG00000090565 +414081 5330413P13Rik MGI:MGI:3041161|Ensembl:ENSMUSG00000086822 +414084 Tnip3 MGI:MGI:3041165|Ensembl:ENSMUSG00000044162|Vega:OTTMUSG00000016677 +414085 9330151L19Rik MGI:MGI:3041168|Ensembl:ENSMUSG00000097061 +414086 9830144P21Rik MGI:MGI:3041171 +414087 A330068G13Rik MGI:MGI:3041176 +414089 Gja6 MGI:MGI:95717|Ensembl:ENSMUSG00000055691|Vega:OTTMUSG00000019585 +414091 A630001O12Rik MGI:MGI:3041181 +414092 A830008E24Rik MGI:MGI:3041183 +414093 A830082N09Rik MGI:MGI:3041184|Ensembl:ENSMUSG00000112280 +414094 Dgkeos MGI:MGI:3041185 +414095 B130034C11Rik MGI:MGI:3041186|Ensembl:ENSMUSG00000093606 +414098 C230096K16Rik MGI:MGI:3041194 +414101 E130317F20Rik MGI:MGI:3041202|Ensembl:ENSMUSG00000091994 +414103 E230032D23Rik MGI:MGI:3041205 +414104 E330016L19Rik MGI:MGI:3041207|Ensembl:ENSMUSG00000085060 +414105 4732465J04Rik MGI:MGI:3041208 +414106 4930417H01Rik MGI:MGI:3041209 +414108 9230114K14Rik MGI:MGI:3041212|Ensembl:ENSMUSG00000097145 +414109 9830163H01Rik MGI:MGI:3041213 +414110 A430072P03Rik MGI:MGI:3041214 +414111 C130083M11Rik MGI:MGI:3041216|Ensembl:ENSMUSG00000106464 +414113 D230040A04Rik MGI:MGI:3041220 +414114 D330037F02Rik MGI:MGI:3041221 +414115 D330050I16Rik MGI:MGI:3041222 +414116 D630024D03Rik MGI:MGI:3041224|Ensembl:ENSMUSG00000085772 +414118 Zmiz1os1 MGI:MGI:3041228 +414119 E330010L02Rik MGI:MGI:3041230 +414120 E330018M18Rik MGI:MGI:3041231 +414121 E430016F16Rik MGI:MGI:3041232|Ensembl:ENSMUSG00000059146 +414123 Mir670hg MGI:MGI:3041234 +414124 F730035M05Rik MGI:MGI:3041236|Ensembl:ENSMUSG00000085298 +414125 F830002L21Rik MGI:MGI:3041237|Ensembl:ENSMUSG00000075184 +414126 G630018N14Rik MGI:MGI:3041239 +414127 G630055G22Rik MGI:MGI:3041240 +414128 G630064G18Rik MGI:MGI:3041241|Ensembl:ENSMUSG00000110242 +414271 A830091E24 - +414279 LOC414279 - +414280 LOC414280 - +414282 LOC414282 - +414326 D930050J11 - +414359 Gm5417 MGI:MGI:3648626 +414361 Gm5418 MGI:MGI:3645206 +414362 LOC414362 - +414363 LOC414363 - +414364 Gm5419 MGI:MGI:3645208 +414758 Zfp950 MGI:MGI:2652824|Ensembl:ENSMUSG00000074733|Vega:OTTMUSG00000033031 +414801 Itprip MGI:MGI:3042776|Ensembl:ENSMUSG00000044948 +414872 Zyg11b MGI:MGI:2685277|Ensembl:ENSMUSG00000034636|Vega:OTTMUSG00000008234 +415115 Neurl2 MGI:MGI:3043305|Ensembl:ENSMUSG00000039873|Vega:OTTMUSG00000001109 +415119 D6Slab17 MGI:MGI:3043544 +425051 D930019O06Rik MGI:MGI:3043219 +431706 Zfp457 MGI:MGI:2664334|Ensembl:ENSMUSG00000055341|Vega:OTTMUSG00000042789 +432396 Zfp652os MGI:MGI:3044900|Ensembl:ENSMUSG00000086191 +432397 M134G01 MGI:MGI:2153537 +432436 Gm5420 MGI:MGI:3645721|Ensembl:ENSMUSG00000056716 +432438 Gm5421 MGI:MGI:3645718 +432442 Akap7 MGI:MGI:1859150|Ensembl:ENSMUSG00000039166|Vega:OTTMUSG00000042011 +432447 Gm9824 MGI:MGI:3641964 +432448 Gm5422 MGI:MGI:3643411 +432449 A230081H15Rik MGI:MGI:4437789 +432450 Nkain2 MGI:MGI:1923447|Ensembl:ENSMUSG00000069670|Vega:OTTMUSG00000047244 +432457 9830137J09Rik MGI:MGI:4437790 +432459 LOC432459 - +432460 Tmem229b-ps MGI:MGI:3643175 +432466 Gm5424 MGI:MGI:3643173|Ensembl:ENSMUSG00000046687 +432467 Hnrnph3 MGI:MGI:1926462|Ensembl:ENSMUSG00000020069|Vega:OTTMUSG00000030869 +432478 Tmprss9 MGI:MGI:3612246|Ensembl:ENSMUSG00000059406 +432479 4930404N11Rik MGI:MGI:1921072|Ensembl:ENSMUSG00000020234|Vega:OTTMUSG00000030362 +432480 Gm1553 MGI:MGI:2686399|Ensembl:ENSMUSG00000094186 +432482 Gm5425 MGI:MGI:3643901 +432486 Gnptab MGI:MGI:3643902|Ensembl:ENSMUSG00000035311|Vega:OTTMUSG00000031924 +432488 Gm17745 MGI:MGI:5009823 +432491 Gm5426 MGI:MGI:3646788 +432494 Gm5427 MGI:MGI:3646787 +432500 Gm29674 MGI:MGI:5588833 +432502 Rpl6l MGI:MGI:3647789 +432508 Cpsf6 MGI:MGI:1913948|Ensembl:ENSMUSG00000055531|Vega:OTTMUSG00000042016 +432516 Myo1a MGI:MGI:107732|Ensembl:ENSMUSG00000025401 +432530 Adcy1 MGI:MGI:99677|Ensembl:ENSMUSG00000020431|Vega:OTTMUSG00000005134 +432534 Gm5429 MGI:MGI:3645014 +432535 Gm12005 MGI:MGI:3651316 +432536 Pom121l12 MGI:MGI:1920677|Ensembl:ENSMUSG00000084135|Vega:OTTMUSG00000005175 +432537 Gm12009 MGI:MGI:3651311 +432543 Gm5430 MGI:MGI:3648216 +432548 Rpsa-ps4 MGI:MGI:3651545 +432549 Gm12138 MGI:MGI:3651749 +432551 Hspd1-ps3 MGI:MGI:3651246 +432552 Fam71b MGI:MGI:3650836|Ensembl:ENSMUSG00000020401|Vega:OTTMUSG00000005491 +432554 Gm12183 MGI:MGI:3652175 +432555 Gm5431 MGI:MGI:3645205|Ensembl:ENSMUSG00000058163|Vega:OTTMUSG00000005524 +432561 Gm9837 MGI:MGI:3642517 +432562 Lyrm7os MGI:MGI:3651880|Ensembl:ENSMUSG00000086789 +432565 Gm12263 MGI:MGI:3650086 +432572 Specc1 MGI:MGI:2442356|Ensembl:ENSMUSG00000042331|Vega:OTTMUSG00000005853 +432577 Gm12712 MGI:MGI:3649929 +432582 Ccdc92b MGI:MGI:3588240|Ensembl:ENSMUSG00000069814|Vega:OTTMUSG00000006181 +432584 Gm11203 MGI:MGI:3650028 +432589 Gm11541 MGI:MGI:3650066|Ensembl:ENSMUSG00000056008|Vega:OTTMUSG00000002038 +432591 Gm11544 MGI:MGI:3650736 +432593 Gm11538 MGI:MGI:3649911 +432596 LOC432596 - +432600 Gm11568 MGI:MGI:3650331|Ensembl:ENSMUSG00000069717|Vega:OTTMUSG00000002207 +432602 Krtap31-2 MGI:MGI:3650789|Ensembl:ENSMUSG00000051481|Vega:OTTMUSG00000002177 +432605 LOC432605 - +432611 Dnaic2 MGI:MGI:2685574|Ensembl:ENSMUSG00000034706|Vega:OTTMUSG00000003426 +432613 Trim80 MGI:MGI:3588186|Ensembl:ENSMUSG00000070332|Vega:OTTMUSG00000003440 +432615 Gm11733 MGI:MGI:3650737|Ensembl:ENSMUSG00000069588|Vega:OTTMUSG00000003802 +432628 Mfsd2b MGI:MGI:3583946|Ensembl:ENSMUSG00000037336|Vega:OTTMUSG00000033541 +432636 Gm5432 MGI:MGI:3649057 +432641 Gm17746 MGI:MGI:5009824 +432649 Gm5434 MGI:MGI:3646221|Ensembl:ENSMUSG00000059301 +432658 LOC432658 - +432665 Rpl21-ps3 MGI:MGI:3646431 +432675 Gm5435 MGI:MGI:3643292 +432676 Gm5436 MGI:MGI:3643291 +432677 Vrtn MGI:MGI:3588197|Ensembl:ENSMUSG00000071235 +432681 Rpl31-ps1 MGI:MGI:3644997 +432701 Ighv6-7 MGI:MGI:3644477|IMGT/GENE-DB:IGHV6-7 +432702 Ighv1-4 MGI:MGI:4439618|IMGT/GENE-DB:IGHV1-4 +432708 Ighv1-59 MGI:MGI:3644474|IMGT/GENE-DB:IGHV1-59 +432709 Ighv8-9 MGI:MGI:3644475|IMGT/GENE-DB:IGHV8-9 +432713 Gm5441 MGI:MGI:3779489|Ensembl:ENSMUSG00000101930 +432715 Gm5442 MGI:MGI:3647655 +432720 Akr1c19 MGI:MGI:2653678|Ensembl:ENSMUSG00000071551|Vega:OTTMUSG00000027684 +432721 Rpl29-ps2 MGI:MGI:3648624 +432723 Gm5444 MGI:MGI:3644242 +432725 Gm5445 MGI:MGI:3644181 +432729 Tcrg-C MGI:MGI:98624 +432730 Gm5446 MGI:MGI:3644854 +432731 Zscan26 MGI:MGI:3531417|Ensembl:ENSMUSG00000022228|Vega:OTTMUSG00000000414 +432732 AK157302 MGI:MGI:3574096 +432735 Vmn1r207-ps MGI:MGI:3650396 +432736 Vmn1r209 MGI:MGI:3650395|Ensembl:ENSMUSG00000071491|Vega:OTTMUSG00000000514 +432742 Gm29675 MGI:MGI:5588834 +432743 Gm5447 MGI:MGI:3644017 +432745 4930447K03Rik MGI:MGI:1921231|Ensembl:ENSMUSG00000113591 +432754 Gm29676 MGI:MGI:5588835 +432760 Gm5449 MGI:MGI:3643792 +432763 Prr7 MGI:MGI:3487246|Ensembl:ENSMUSG00000034686 +432767 Eif1-ps2 MGI:MGI:3643793 +432768 Gm5451 MGI:MGI:3643790 +432769 Zfp708 MGI:MGI:3040674|Ensembl:ENSMUSG00000058883|Vega:OTTMUSG00000049318 +432770 Rslcan18 MGI:MGI:5433745|Ensembl:ENSMUSG00000074824|Vega:OTTMUSG00000049320 +432777 D630045M09Rik MGI:MGI:3583897|Ensembl:ENSMUSG00000113346 +432779 Lrrc14b MGI:MGI:2145269|Ensembl:ENSMUSG00000021579|Vega:OTTMUSG00000034206 +432789 Gm5452 MGI:MGI:3645281 +432798 Gm5453 MGI:MGI:3648523 +432800 Gm5454 MGI:MGI:3648286 +432801 Gm16416 MGI:MGI:3646635 +432803 Gm5455 MGI:MGI:3646920 +432812 BC052688 MGI:MGI:3583898 +432817 Gm5456 MGI:MGI:3643775 +432822 Gm5457 MGI:MGI:3646665 +432825 Gm5458 MGI:MGI:3646663|Ensembl:ENSMUSG00000095024|Vega:OTTMUSG00000036309 +432830 Gm17747 MGI:MGI:5009825 +432834 Gm5459 MGI:MGI:3643518 +432838 Gm5460 MGI:MGI:3643519|Ensembl:ENSMUSG00000072624 +432839 Gprin2 MGI:MGI:2444560|Ensembl:ENSMUSG00000071531 +432842 LOC432842 - +432852 LOC432852 - +432855 Zfhx2os MGI:MGI:3620246|Ensembl:ENSMUSG00000093452 +432860 B020004C17Rik MGI:MGI:3588236|Ensembl:ENSMUSG00000096144 +432864 Gm5461 MGI:MGI:3646225 +432865 Rps12-ps2 MGI:MGI:3646224 +432867 Defb48 MGI:MGI:3646223|Ensembl:ENSMUSG00000075574|Vega:OTTMUSG00000020959 +432868 Gm5463 MGI:MGI:3779490 +432870 Gm5464 MGI:MGI:3643060|Ensembl:ENSMUSG00000075553 +432879 Kbtbd6 MGI:MGI:3643058|Ensembl:ENSMUSG00000075502|Vega:OTTMUSG00000055529 +432881 Gm5466 MGI:MGI:3647828 +432885 LOC432885 - +432910 Trav13-3 MGI:MGI:3652331|IMGT/GENE-DB:TRAV13-3 +432939 Gm5468 MGI:MGI:3648948 +432940 Otulin MGI:MGI:3577015|Ensembl:ENSMUSG00000046034 +432945 Gm16294 MGI:MGI:3645121|Ensembl:ENSMUSG00000056332 +432946 Gm5469 MGI:MGI:3645122 +432947 Gm5470 MGI:MGI:3645123 +432950 Gm5471 MGI:MGI:3648310 +432951 Gm5472 MGI:MGI:3648309 +432956 D030024E09Rik MGI:MGI:3041198 +432958 Gm20740 MGI:MGI:5434096 +432959 Gm5473 MGI:MGI:3648307 +432961 LOC432961 - +432964 K230010J24Rik MGI:MGI:3588184|Ensembl:ENSMUSG00000102018|Vega:OTTMUSG00000045037 +432971 A130088B03Rik MGI:MGI:4437731 +432982 Gm5475 MGI:MGI:3646320|Ensembl:ENSMUSG00000087444|Vega:OTTMUSG00000033274 +432985 Gm5476 MGI:MGI:3646316 +432986 Gm5477 MGI:MGI:3646317 +432987 Gm5478 MGI:MGI:3646318|Ensembl:ENSMUSG00000095241 +432988 Gm9918 MGI:MGI:3646315|Ensembl:ENSMUSG00000097050|Vega:OTTMUSG00000061789 +432989 D930007P13Rik MGI:MGI:3715731|Ensembl:ENSMUSG00000097003 +432993 Gm5479 MGI:MGI:3643380 +432995 Smim22 MGI:MGI:3643379|Ensembl:ENSMUSG00000096215|Vega:OTTMUSG00000044648 +432999 A930007A09Rik MGI:MGI:3045309 +433003 Gm5481 MGI:MGI:3648103 +433004 B830017H08Rik MGI:MGI:3045365 +433016 Gm5483 MGI:MGI:3645124|Ensembl:ENSMUSG00000079597 +433022 Plcxd2 MGI:MGI:3647874|Ensembl:ENSMUSG00000087141|Vega:OTTMUSG00000024723 +433023 Gm5485 MGI:MGI:3647875|Ensembl:ENSMUSG00000110573|Vega:OTTMUSG00000061550 +433024 Gm5486 MGI:MGI:3647871 +433027 Gm5487 MGI:MGI:3647872 +433031 Olfr194 MGI:MGI:3030028|Ensembl:ENSMUSG00000063020|Vega:OTTMUSG00000059122 +433047 Gm20741 MGI:MGI:5434097 +433050 Rpl26-ps4 MGI:MGI:3644695 +433053 LOC433053 - +433058 Ppp1r2-ps6 MGI:MGI:3644697 +433063 Gm5491 MGI:MGI:3644969 +433064 Gm17748 MGI:MGI:5009826 +433070 Vmn2r96 MGI:MGI:3644514|Ensembl:ENSMUSG00000091679|Vega:OTTMUSG00000039021 +433073 Gm5492 MGI:MGI:3644513 +433078 Gm5493 MGI:MGI:3644511 +433082 D930048G16Rik MGI:MGI:4437732 +433091 Pnpla1 MGI:MGI:3617850|Ensembl:ENSMUSG00000043286|Vega:OTTMUSG00000024254 +433099 Ly6g6f MGI:MGI:3616082|Ensembl:ENSMUSG00000034923|Vega:OTTMUSG00000014958 +433100 AA388235 MGI:MGI:3035178 +433102 Sfta2 MGI:MGI:3643293|Ensembl:ENSMUSG00000090509|Vega:OTTMUSG00000037247 +433107 Esp6 MGI:MGI:3643294|Ensembl:ENSMUSG00000092043 +433111 F630040K05Rik MGI:MGI:4437734|Ensembl:ENSMUSG00000097727 +433125 Rpl21-ps6 MGI:MGI:3643554 +433129 Obox6-ps1 MGI:MGI:3643552 +433131 Gm5497 MGI:MGI:3646432 +433134 Gm20742 MGI:MGI:5434098 +433141 Rpsa-ps7 MGI:MGI:3643805 +433144 Gm5499 MGI:MGI:3643804 +433158 Gm5500 MGI:MGI:3647082 +433161 Gm5501 MGI:MGI:3644023 +433170 Gm5503 MGI:MGI:3646950 +433171 Gm10549 MGI:MGI:3641986 +433177 Gm5504 MGI:MGI:3646951 +433178 Spink14 MGI:MGI:3646952|Ensembl:ENSMUSG00000051050|Vega:OTTMUSG00000033947 +433180 Spink6 MGI:MGI:3648654|Ensembl:ENSMUSG00000055095 +433181 Spink11 MGI:MGI:3588289|Ensembl:ENSMUSG00000073573|Vega:OTTMUSG00000049755 +433182 Eno1b MGI:MGI:3648653|Ensembl:ENSMUSG00000059040 +433184 Gm5507 MGI:MGI:3648656 +433193 Rps15-ps3 MGI:MGI:3645421 +433197 Gm29677 MGI:MGI:5588836 +433198 LOC433198 - +433202 Gm9925 MGI:MGI:3641738 +433204 Gm5509 MGI:MGI:3645239 +433208 D030046N08Rik MGI:MGI:3645234 +433215 Tmem262 MGI:MGI:3690536|Ensembl:ENSMUSG00000047733|Vega:OTTMUSG00000028975 +433216 Gm5510 MGI:MGI:3648472 +433217 Gm16437 MGI:MGI:3644508 +433221 Gm5511 MGI:MGI:3779492 +433224 Gm5512 MGI:MGI:3645436|Ensembl:ENSMUSG00000112693 +433225 Gm5513 MGI:MGI:3645437 +433227 LOC433227 - +433229 Gm5514 MGI:MGI:3645435 +433230 Nsa2-ps1 MGI:MGI:3648670 +433235 Gm5517 MGI:MGI:3648671 +433238 Gm5518 MGI:MGI:3648673 +433241 Gm5519 MGI:MGI:3645618 +433247 Cyp2c68 MGI:MGI:3612287|Ensembl:ENSMUSG00000074882|Vega:OTTMUSG00000028477 +433251 Rpl13a-ps1 MGI:MGI:3648883 +433256 Acsl5 MGI:MGI:1919129|Ensembl:ENSMUSG00000024981 +433261 Gm5521 MGI:MGI:3645827 +433270 E330040D14Rik MGI:MGI:3649088 +433271 Gm5522 MGI:MGI:3649087 +433273 Gm5523 MGI:MGI:3649089|Ensembl:ENSMUSG00000097711 +433278 Khdc1c MGI:MGI:3583007|Ensembl:ENSMUSG00000041722|Vega:OTTMUSG00000033756 +433281 Gm5524 MGI:MGI:3646041|Ensembl:ENSMUSG00000101514 +433283 Gm5525 MGI:MGI:3646042 +433287 Gm15455 MGI:MGI:3705563 +433292 Nms MGI:MGI:3583618|Ensembl:ENSMUSG00000067604|Vega:OTTMUSG00000035128 +433294 Mettl21c MGI:MGI:3611450|Ensembl:ENSMUSG00000047343|Vega:OTTMUSG00000026592 +433297 Gm5526 MGI:MGI:3643066 +433305 Gm5527 MGI:MGI:3646585 +433313 Rpl17-ps1 MGI:MGI:3652107 +433315 Gm13749 MGI:MGI:3649721|Ensembl:ENSMUSG00000044689 +433316 LOC433316 - +433319 Gm5528 MGI:MGI:3643453 +433323 Sgpp2 MGI:MGI:3589109|Ensembl:ENSMUSG00000032908|Vega:OTTMUSG00000047786 +433326 Gm5529 MGI:MGI:3646377 +433328 Gm5530 MGI:MGI:3646374 +433332 Gm9991 MGI:MGI:3643217 +433347 Gm28856 MGI:MGI:5579562|Ensembl:ENSMUSG00000100106 +433354 LOC433354 - +433365 Teddm1b MGI:MGI:3646829|Ensembl:ENSMUSG00000043282|Vega:OTTMUSG00000049772 +433367 Gm5532 MGI:MGI:3646828|Ensembl:ENSMUSG00000073535 +433368 Gm15428 MGI:MGI:3642670 +433374 Gm20743 MGI:MGI:5434099|Ensembl:ENSMUSG00000104117 +433375 Creg1 MGI:MGI:1344382|Ensembl:ENSMUSG00000040713|Vega:OTTMUSG00000021575 +433384 Gm5533 MGI:MGI:3647595 +433386 Ccdc185 MGI:MGI:3618292|Ensembl:ENSMUSG00000043429|Vega:OTTMUSG00000050484 +433387 Rpl21-ps1 MGI:MGI:3647596 +433390 Gm29678 MGI:MGI:5588837|Ensembl:ENSMUSG00000103644 +433406 Gm13363 MGI:MGI:3651407 +433408 Gm13375 MGI:MGI:3649913 +433410 Gm13418 MGI:MGI:3650378 +433415 Gm13420 MGI:MGI:3649917|Ensembl:ENSMUSG00000079497|Vega:OTTMUSG00000012042 +433416 Gm13547 MGI:MGI:3650473|Ensembl:ENSMUSG00000075425|Vega:OTTMUSG00000012686 +433423 Gm12285 MGI:MGI:3649229 +433424 Zeb2os MGI:MGI:3652108|Ensembl:ENSMUSG00000052248 +433426 Gm13490 MGI:MGI:3650821|Ensembl:ENSMUSG00000085014 +433428 LOC433428 - +433432 Gm13624 MGI:MGI:3649579 +433449 Olfr1197 MGI:MGI:3031031|Ensembl:ENSMUSG00000075119|Vega:OTTMUSG00000014002 +433456 4631405J19Rik MGI:MGI:3045383|Ensembl:ENSMUSG00000075027 +433458 Gm13880 MGI:MGI:3649539 +433461 LOC433461 - +433463 Gm13929 MGI:MGI:3649396 +433464 Gm13991 MGI:MGI:3651689 +433466 Jmjd7 MGI:MGI:3845785|Ensembl:ENSMUSG00000098789|Vega:OTTMUSG00000044911 +433468 Gm14058 MGI:MGI:3649507 +433470 AA467197 MGI:MGI:3034182|Ensembl:ENSMUSG00000033213|Vega:OTTMUSG00000015673 +433478 Gm14038 MGI:MGI:3650657 +433481 Gm5535 MGI:MGI:3645019|Ensembl:ENSMUSG00000074758 +433483 Gm14135 MGI:MGI:3649300 +433485 Syndig1 MGI:MGI:3702158|Ensembl:ENSMUSG00000074736|Vega:OTTMUSG00000015750 +433486 Gm14151 MGI:MGI:3651016|Ensembl:ENSMUSG00000079006|Vega:OTTMUSG00000015806 +433490 Defb45 MGI:MGI:3650541|Ensembl:ENSMUSG00000062124|Vega:OTTMUSG00000015859 +433492 Bpifb9b MGI:MGI:1918675|Ensembl:ENSMUSG00000067996|Vega:OTTMUSG00000015915 +433502 Wfdc6b MGI:MGI:3575430|Ensembl:ENSMUSG00000070531|Vega:OTTMUSG00000001097 +433503 Gm29679 MGI:MGI:5588838 +433515 Gm14323 MGI:MGI:3650742 +433520 Gm14403 MGI:MGI:3649813 +433546 Gm14231 MGI:MGI:3652156 +433550 Gm13675 MGI:MGI:3649532 +433577 LOC433577 - +433586 Maml3 MGI:MGI:2389461|Ensembl:ENSMUSG00000061143|Vega:OTTMUSG00000026673 +433594 Gm5537 MGI:MGI:3643179 +433597 Gm5538 MGI:MGI:3779495|Ensembl:ENSMUSG00000090527|Vega:OTTMUSG00000052111 +433598 Gm5539 MGI:MGI:3644451 +433604 Gm5540 MGI:MGI:3644824 +433611 LOC433611 - +433619 Kprp MGI:MGI:1920981|Ensembl:ENSMUSG00000059832|Vega:OTTMUSG00000042183 +433623 Gm5541 MGI:MGI:3645005 +433624 Gm5542 MGI:MGI:3779496 +433625 Gm5543 MGI:MGI:3645007 +433630 Rpl21-ps11 MGI:MGI:3648207 +433632 Gm5544 MGI:MGI:3648209 +433634 Gm5546 MGI:MGI:3648205 +433637 Gm5547 MGI:MGI:3648206|Ensembl:ENSMUSG00000104835 +433638 I830077J02Rik MGI:MGI:3588284|Ensembl:ENSMUSG00000074342|Vega:OTTMUSG00000026612 +433646 1700061I17Rik MGI:MGI:1920612|Ensembl:ENSMUSG00000028009 +433653 Gimd1 MGI:MGI:3647547|Ensembl:ENSMUSG00000091721|Vega:OTTMUSG00000047632 +433658 Gm15688 MGI:MGI:3647549|Ensembl:ENSMUSG00000089737 +433667 Ankrd13c MGI:MGI:2139746|Ensembl:ENSMUSG00000039988|Vega:OTTMUSG00000052510 +433686 Gm5550 MGI:MGI:3643895 +433687 Gm11824 MGI:MGI:3651313 +433688 Gm11836 MGI:MGI:3650063 +433693 Akirin2 MGI:MGI:1889364|Ensembl:ENSMUSG00000028291|Vega:OTTMUSG00000006351 +433698 Fam205a1 MGI:MGI:3651059|Ensembl:ENSMUSG00000078721|Vega:OTTMUSG00000006791 +433700 Spag8 MGI:MGI:3056295|Ensembl:ENSMUSG00000066196|Vega:OTTMUSG00000007020 +433702 Ncbp1 MGI:MGI:1891840|Ensembl:ENSMUSG00000028330|Vega:OTTMUSG00000006833 +433711 Gm12580 MGI:MGI:3651872 +433712 Rpsa-ps11 MGI:MGI:3649246 +433715 Gm11249 MGI:MGI:3650834 +433716 Gm11222 MGI:MGI:3651632 +433719 Gm11487 MGI:MGI:3650704|Ensembl:ENSMUSG00000066137|Vega:OTTMUSG00000001246 +433739 Gm12799 MGI:MGI:3652118 +433742 Gm12722 MGI:MGI:3652209 +433743 Gm12906 MGI:MGI:3650884 +433745 Gm12816 MGI:MGI:3649628 +433746 Gm12830 MGI:MGI:3649998|Ensembl:ENSMUSG00000055198|Vega:OTTMUSG00000008584 +433748 Llph-ps1 MGI:MGI:3649506 +433749 Gm12844 MGI:MGI:3651053 +433751 Gm12866 MGI:MGI:3649462|Ensembl:ENSMUSG00000066060 +433752 Frg2f1 MGI:MGI:3035485|Ensembl:ENSMUSG00000087385|Vega:OTTMUSG00000009434 +433759 Hdac1 MGI:MGI:108086|Ensembl:ENSMUSG00000028800|Vega:OTTMUSG00000009661 +433766 Trim63 MGI:MGI:2447992|Ensembl:ENSMUSG00000028834|Vega:OTTMUSG00000010606 +433770 Gm12986 MGI:MGI:3651584 +433771 Minos1 MGI:MGI:1913628|Ensembl:ENSMUSG00000050608|Vega:OTTMUSG00000009904 +433776 Gm13050 MGI:MGI:3650664 +433779 Gm13119 MGI:MGI:3651680|Ensembl:ENSMUSG00000070619|Vega:OTTMUSG00000010537 +433790 Gm13241 MGI:MGI:3649920 +433791 Zfp992 MGI:MGI:3700963|Ensembl:ENSMUSG00000070605|Vega:OTTMUSG00000011097 +433801 Gm13212 MGI:MGI:3651014|Ensembl:ENSMUSG00000078502|Vega:OTTMUSG00000010965 +433804 Zfp985 MGI:MGI:3651986|Ensembl:ENSMUSG00000065999|Vega:OTTMUSG00000010673 +433806 Chchd2-ps MGI:MGI:3649942 +433809 Rnf207 MGI:MGI:2684989|Ensembl:ENSMUSG00000058498|Vega:OTTMUSG00000010578 +433813 Pusl1 MGI:MGI:3047787|Ensembl:ENSMUSG00000051557|Vega:OTTMUSG00000010889 +433840 Gm15730 MGI:MGI:3783173 +433844 Gm10482 MGI:MGI:3644444 +433845 Gm10481 MGI:MGI:3708707 +433855 AI506816 MGI:MGI:2140929|Ensembl:ENSMUSG00000105987 +433862 Gm5551 MGI:MGI:3642937 +433864 Nom1 MGI:MGI:1861749|Ensembl:ENSMUSG00000001569|Vega:OTTMUSG00000026730 +433865 Gm5552 MGI:MGI:3643001 +433868 3110082J24Rik MGI:MGI:3641994|Ensembl:ENSMUSG00000086815|Vega:OTTMUSG00000054790 +433873 Gm9903 MGI:MGI:3646113|Ensembl:ENSMUSG00000097271|Vega:OTTMUSG00000055658 +433874 Gm5553 MGI:MGI:3646114 +433882 Gm16223 MGI:MGI:3648966|Ensembl:ENSMUSG00000067285|Vega:OTTMUSG00000031875 +433883 Gm5554 MGI:MGI:3648967 +433885 Gm5555 MGI:MGI:3648970 +433899 Grxcr1 MGI:MGI:3577767|Ensembl:ENSMUSG00000068082|Vega:OTTMUSG00000034596 +433904 Ociad2 MGI:MGI:1916377|Ensembl:ENSMUSG00000029153|Vega:OTTMUSG00000026763 +433912 Rpl7-ps7 MGI:MGI:3644615 +433914 Gm5558 MGI:MGI:3644616 +433921 Gm5559 MGI:MGI:3779498 +433923 Gm5560 MGI:MGI:3647980 +433926 Lrrc8b MGI:MGI:2141353|Ensembl:ENSMUSG00000070639|Vega:OTTMUSG00000053870 +433931 Pigg MGI:MGI:3576484|Ensembl:ENSMUSG00000029263|Vega:OTTMUSG00000028929 +433938 Mn1 MGI:MGI:1261813|Ensembl:ENSMUSG00000070576|Vega:OTTMUSG00000028670 +433940 Fam222a MGI:MGI:3605543|Ensembl:ENSMUSG00000041930|Vega:OTTMUSG00000014487 +433941 Gm5561 MGI:MGI:3804971 +433943 Gstm2-ps1 MGI:MGI:3648223 +433944 Tbx3os2 MGI:MGI:3801954|Ensembl:ENSMUSG00000086847 +433945 Gm5563 MGI:MGI:3648222 +433955 Gm5564 MGI:MGI:3645018 +433956 Dnaaf5 MGI:MGI:3616079|Ensembl:ENSMUSG00000025857|Vega:OTTMUSG00000025148 +433961 Gm5565 MGI:MGI:3779499|Ensembl:ENSMUSG00000104752|Vega:OTTMUSG00000055152 +433966 5730422E09Rik MGI:MGI:1917793|Ensembl:ENSMUSG00000097191 +433968 Gm5566 MGI:MGI:3648428 +434003 Gm13848 MGI:MGI:3651996|Ensembl:ENSMUSG00000084973 +434008 Tmem178b MGI:MGI:3647581|Ensembl:ENSMUSG00000057716|Vega:OTTMUSG00000042925 +434016 Vmn1r7 MGI:MGI:2159467|Ensembl:ENSMUSG00000093696|Vega:OTTMUSG00000039849 +434017 Vmn1r20 MGI:MGI:3644381|Ensembl:ENSMUSG00000093679|Vega:OTTMUSG00000039930 +434018 4930533I22Rik MGI:MGI:3612486 +434019 Gm5570 MGI:MGI:3644382|Ensembl:ENSMUSG00000073045 +434023 Bj2 - +434024 Igkv1-122 MGI:MGI:4439722|IMGT/GENE-DB:IGKV1-122 +434025 Igkv9-120 MGI:MGI:3647784|IMGT/GENE-DB:IGKV9-120 +434026 Igkv2-116 MGI:MGI:3647785|IMGT/GENE-DB:IGKV2-116 +434028 Igkv1-99 MGI:MGI:4439724|IMGT/GENE-DB:IGKV1-99 +434031 Igkv10-95 MGI:MGI:3644598|IMGT/GENE-DB:IGKV10-95 +434033 Igkv4-91 MGI:MGI:3642277|IMGT/GENE-DB:IGKV4-91 +434034 Igkv4-90 MGI:MGI:4439830|IMGT/GENE-DB:IGKV4-90 +434035 LOC434035 - +434036 Igkv13-85 MGI:MGI:4439827|IMGT/GENE-DB:IGKV13-85 +434037 Igkv12-47 MGI:MGI:3644595|IMGT/GENE-DB:IGKV12-47 +434039 Igkv6-32 MGI:MGI:3641634|IMGT/GENE-DB:IGKV6-32 +434040 Igkv8-28 MGI:MGI:3642251|IMGT/GENE-DB:IGKV8-28 +434041 Igkv8-27 MGI:MGI:4439868|IMGT/GENE-DB:IGKV8-27 +434047 Gm5575 MGI:MGI:3647974 +434050 Gm5576 MGI:MGI:3644832 +434057 Nat8b-ps MGI:MGI:3644831 +434064 Gm5577 MGI:MGI:3648213|Ensembl:ENSMUSG00000084950 +434065 Gm1965 MGI:MGI:3584270|Ensembl:ENSMUSG00000090254 +434076 Gm15519 MGI:MGI:3782965 +434077 Gm5578 MGI:MGI:3645010 +434080 Gm5580 MGI:MGI:3646594 +434083 Mug4-ps MGI:MGI:101843 +434089 Gm10010 MGI:MGI:3641978 +434094 Gm5581 MGI:MGI:3643462 +434095 Gm5582 MGI:MGI:3643463 +434109 Gm5583 MGI:MGI:3646061 +434110 Vmn2r38 MGI:MGI:3757869|Ensembl:ENSMUSG00000095773|Vega:OTTMUSG00000037991 +434113 Vmn2r44 MGI:MGI:3643088|Ensembl:ENSMUSG00000094098|Vega:OTTMUSG00000038068 +434117 Vmn2r50 MGI:MGI:3643086|Ensembl:ENSMUSG00000094606|Vega:OTTMUSG00000038507 +434121 Sult2a4 MGI:MGI:3645854|Ensembl:ENSMUSG00000074377|Vega:OTTMUSG00000021841 +434123 Obox8 MGI:MGI:3645855 +434127 Gm5586 MGI:MGI:3645853 +434128 Pnmal2 MGI:MGI:3645856|Ensembl:ENSMUSG00000070802|Vega:OTTMUSG00000058182 +434130 Ccdc8 MGI:MGI:3612184|Ensembl:ENSMUSG00000041117|Vega:OTTMUSG00000037103 +434147 D930028M14Rik MGI:MGI:3687343|Ensembl:ENSMUSG00000074274 +434148 Gm5587 MGI:MGI:3645641 +434156 Eid2b MGI:MGI:1924095|Ensembl:ENSMUSG00000070705|Vega:OTTMUSG00000059052 +434166 Gm5589 MGI:MGI:3779501 +434168 Gm5590 MGI:MGI:3645451 +434171 Gm5591 MGI:MGI:3648692|Ensembl:ENSMUSG00000060565|Vega:OTTMUSG00000048816 +434172 Gm5592 MGI:MGI:3648691|Ensembl:ENSMUSG00000072259|Vega:OTTMUSG00000035888 +434174 Hmgb1-ps7 MGI:MGI:3648695 +434175 Ccnb1-ps MGI:MGI:3648694|Ensembl:ENSMUSG00000048574 +434177 Gm5594 MGI:MGI:3648693 +434178 Zfp141 MGI:MGI:3584269|Ensembl:ENSMUSG00000092416|Vega:OTTMUSG00000037906 +434179 Zfp975 MGI:MGI:3648690|Ensembl:ENSMUSG00000069727|Vega:OTTMUSG00000022456 +434186 Gm16478 MGI:MGI:3648411 +434189 Gm5596 MGI:MGI:3646954 +434197 Fam169b MGI:MGI:3644026|Ensembl:ENSMUSG00000074071|Vega:OTTMUSG00000031025 +434198 B130024G19Rik MGI:MGI:3604353|Ensembl:ENSMUSG00000100005 +434200 Gm5597 MGI:MGI:3779502 +434203 Slc28a1 MGI:MGI:3605073|Ensembl:ENSMUSG00000025726|Vega:OTTMUSG00000031345 +434204 Whamm MGI:MGI:2142282|Ensembl:ENSMUSG00000045795|Vega:OTTMUSG00000059180 +434205 Gm20744 MGI:MGI:5434100|Ensembl:ENSMUSG00000109145 +434215 Lrrc32 MGI:MGI:93882|Ensembl:ENSMUSG00000090958|Vega:OTTMUSG00000058874 +434218 Trim34b MGI:MGI:4821264|Ensembl:ENSMUSG00000090215|Vega:OTTMUSG00000019188 +434219 Trim30c MGI:MGI:4821257 +434223 Gm1966 MGI:MGI:3584360 +434225 Platr28 MGI:MGI:3645719 +434227 Gm5599 MGI:MGI:3644531 +434228 Gm5600 MGI:MGI:3645703 +434232 Iqck MGI:MGI:3612188|Ensembl:ENSMUSG00000073856|Vega:OTTMUSG00000025725 +434233 Gm5601 MGI:MGI:3647492 +434234 Rexo5 MGI:MGI:1919402|Ensembl:ENSMUSG00000030924|Vega:OTTMUSG00000025657 +434246 Trim72 MGI:MGI:3612190|Ensembl:ENSMUSG00000042828|Vega:OTTMUSG00000023332 +434249 Gm5602 MGI:MGI:3645136 +434253 Rpl21-ps13 MGI:MGI:3649022 +434261 Krt8-ps MGI:MGI:3779503 +434264 Sult2a5 MGI:MGI:3648378|Ensembl:ENSMUSG00000078799|Vega:OTTMUSG00000021844 +434274 LOC434274 - +434278 B020031H02Rik MGI:MGI:3588231 +434279 Gm5606 MGI:MGI:3647910 +434280 Gm5607 MGI:MGI:3645522|Ensembl:ENSMUSG00000047935 +434282 Gm5608 MGI:MGI:3779504 +434285 BB014433 MGI:MGI:2142823|Ensembl:ENSMUSG00000049008|Vega:OTTMUSG00000033928 +434304 Gm5609 MGI:MGI:3643259 +434310 AY512931 MGI:MGI:3525069|Ensembl:ENSMUSG00000066158 +434317 LOC434317 - +434325 Tmem221 MGI:MGI:3525074|Ensembl:ENSMUSG00000043664|Vega:OTTMUSG00000062162 +434339 Ap3s1-ps2 MGI:MGI:1929217 +434341 Nlrc5 MGI:MGI:3612191|Ensembl:ENSMUSG00000074151|Vega:OTTMUSG00000033926 +434348 LOC434348 - +434350 9430091E24Rik MGI:MGI:1924618 +434352 LOC434352 - +434353 A330074K22Rik MGI:MGI:3045392|Ensembl:ENSMUSG00000097960 +434373 Gm5611 MGI:MGI:3647121 +434375 Gm5612 MGI:MGI:3647118 +434377 Zfp560 MGI:MGI:1915280|Ensembl:ENSMUSG00000045519|Vega:OTTMUSG00000032771 +434378 7030419G21Rik MGI:MGI:3045384 +434391 LOC434391 - +434394 Gm5614 MGI:MGI:3644422 +434396 Gm5615 MGI:MGI:3647347|Ensembl:ENSMUSG00000074448|Vega:OTTMUSG00000044741 +434401 Gm5616 MGI:MGI:3646416 +434402 Gm5617 MGI:MGI:3643566|Ensembl:ENSMUSG00000042293|Vega:OTTMUSG00000062752 +434404 Rps6-ps3 MGI:MGI:3643565 +434410 Gm17749 MGI:MGI:5009827 +434412 Gm20745 MGI:MGI:5434101|Ensembl:ENSMUSG00000111841 +434423 Dppa5a MGI:MGI:101800|Ensembl:ENSMUSG00000060461|Vega:OTTMUSG00000019688 +434426 Gm5619 MGI:MGI:3643807 +434428 Gm5620 MGI:MGI:3647798 +434434 Gm5621 MGI:MGI:3646701 +434436 Lsmem2 MGI:MGI:3612240 +434437 Amt MGI:MGI:3646700|Ensembl:ENSMUSG00000032607|Vega:OTTMUSG00000032968 +434438 Ccdc36 MGI:MGI:3612242|Ensembl:ENSMUSG00000047220|Vega:OTTMUSG00000050756 +434439 BC048562 MGI:MGI:3618861|Ensembl:ENSMUSG00000050641|Vega:OTTMUSG00000050822 +434440 Fbxw20 MGI:MGI:3584372|Ensembl:ENSMUSG00000061701|Vega:OTTMUSG00000027441 +434459 Gm5622 MGI:MGI:3646060|Ensembl:ENSMUSG00000079244|Vega:OTTMUSG00000033238 +434460 Rps15a-ps2 MGI:MGI:3643316 +434476 Gm5624 MGI:MGI:3646247 +434484 Sp140 MGI:MGI:3702467|Ensembl:ENSMUSG00000070031|Vega:OTTMUSG00000030222 +434490 Gm5626 MGI:MGI:3779505 +434510 Gm5627 MGI:MGI:3645308|Ensembl:ENSMUSG00000093812|Vega:OTTMUSG00000042314 +434514 Vmn2r-ps17 MGI:MGI:3761372 +434540 Psg20 MGI:MGI:1891352|Ensembl:ENSMUSG00000063305|Vega:OTTMUSG00000017163 +434555 Zscan4a MGI:MGI:3708481|Ensembl:ENSMUSG00000110097 +434585 Gm5628 MGI:MGI:3779506 +434586 Igkv4-71 MGI:MGI:4439654|IMGT/GENE-DB:IGKV4-71 +434608 LOC434608 - +434609 Ighv1-84 MGI:MGI:3644235|IMGT/GENE-DB:IGHV1-84 +434616 Gm5630 MGI:MGI:3647174 +434624 Ftl1-ps2 MGI:MGI:5434102 +434674 Slc22a28 MGI:MGI:3645714|Ensembl:ENSMUSG00000063590 +434676 Scgb1b19 MGI:MGI:3646447|Ensembl:ENSMUSG00000095232|Vega:OTTMUSG00000045845 +434685 Igkv8-23-1 MGI:MGI:4947960 +434689 Gm10220 MGI:MGI:3798181|Ensembl:ENSMUSG00000067698|Vega:OTTMUSG00000036614 +434693 Mrto4-ps2 MGI:MGI:3779507 +434701 Vmn2r113 MGI:MGI:3648972|Ensembl:ENSMUSG00000092111|Vega:OTTMUSG00000039954 +434721 Gm14332 MGI:MGI:3649936 +434724 Gm14367 MGI:MGI:3705868 +434725 Btbd35f7 MGI:MGI:3709265|Ensembl:ENSMUSG00000095814|Vega:OTTMUSG00000016453 +434726 Fthl17b MGI:MGI:3642940|Ensembl:ENSMUSG00000078208|Vega:OTTMUSG00000017482 +434727 Fthl17c MGI:MGI:3705221|Ensembl:ENSMUSG00000060685|Vega:OTTMUSG00000016933 +434728 Fthl17-ps1 MGI:MGI:3705856 +434729 Fthl17f MGI:MGI:3642941|Ensembl:ENSMUSG00000072249|Vega:OTTMUSG00000016864 +434756 Akap14 MGI:MGI:3618288|Ensembl:ENSMUSG00000036551|Vega:OTTMUSG00000017126 +434758 Rhox3h MGI:MGI:3704137|Ensembl:ENSMUSG00000071769|Vega:OTTMUSG00000017154 +434759 Rhox4c MGI:MGI:3613386|Ensembl:ENSMUSG00000079635|Vega:OTTMUSG00000017142 +434760 Rhox2d MGI:MGI:3648779|Ensembl:ENSMUSG00000095698|Vega:OTTMUSG00000017137 +434764 Rhox2f MGI:MGI:3770275|Ensembl:ENSMUSG00000095741|Vega:OTTMUSG00000017143 +434766 Rhox2g MGI:MGI:3648776|Ensembl:ENSMUSG00000079629|Vega:OTTMUSG00000017152 +434768 Rhox8 MGI:MGI:3579898|Ensembl:ENSMUSG00000064137|Vega:OTTMUSG00000017129 +434769 Rhox10 MGI:MGI:3580249|Ensembl:ENSMUSG00000053909|Vega:OTTMUSG00000017177 +434775 Gm5636 MGI:MGI:3645717 +434778 Ccdc160 MGI:MGI:3588225|Ensembl:ENSMUSG00000073207|Vega:OTTMUSG00000017349 +434782 Gm5637 MGI:MGI:3648120 +434784 Ldoc1 MGI:MGI:2685212|Ensembl:ENSMUSG00000057615|Vega:OTTMUSG00000017589 +434788 Gm5638 MGI:MGI:3648121 +434794 Xlr4a MGI:MGI:3574098|Ensembl:ENSMUSG00000079845|Vega:OTTMUSG00000017711 +434795 Gm5639 MGI:MGI:3645127 +434797 Gm5640 MGI:MGI:3645126|Ensembl:ENSMUSG00000079534|Vega:OTTMUSG00000020730 +434800 Smim9 MGI:MGI:3588243|Ensembl:ENSMUSG00000073094|Vega:OTTMUSG00000020853 +434807 Gm5641 MGI:MGI:3645731 +434825 Gm14858 MGI:MGI:3705120|Ensembl:ENSMUSG00000085568 +434843 Rps12-ps11 MGI:MGI:3646126 +434858 Gm5643 MGI:MGI:3642955 +434860 Gm5644 MGI:MGI:3646381 +434863 Gm15128 MGI:MGI:3712219|Ensembl:ENSMUSG00000095872|Vega:OTTMUSG00000019145 +434864 Gm15107 MGI:MGI:3713328|Ensembl:ENSMUSG00000072930|Vega:OTTMUSG00000019001 +434865 Luzp4 MGI:MGI:3708816|Ensembl:ENSMUSG00000079387|Vega:OTTMUSG00000018982 +434866 Gm15127 MGI:MGI:3711248|Ensembl:ENSMUSG00000096834|Vega:OTTMUSG00000019138 +434869 Gm15097 MGI:MGI:3710639|Ensembl:ENSMUSG00000094378|Vega:OTTMUSG00000018988 +434874 Gm5645 MGI:MGI:3643221 +434879 Gm5646 MGI:MGI:3643220 +434881 Samt2 MGI:MGI:3646587|Ensembl:ENSMUSG00000072888|Vega:OTTMUSG00000019262 +434885 Gm15163 MGI:MGI:3642430 +434903 Mageb4 MGI:MGI:2148568|Ensembl:ENSMUSG00000035427|Vega:OTTMUSG00000017949 +434907 Gm5648 MGI:MGI:3647868 +434935 Gm21943 MGI:MGI:5439394|Ensembl:ENSMUSG00000096122|Vega:OTTMUSG00000045362 +434960 Gm20747 MGI:MGI:5434103|Ensembl:ENSMUSG00000094729|Vega:OTTMUSG00000048519 +435145 Shisa8 MGI:MGI:2146080|Ensembl:ENSMUSG00000096883 +435205 Taar7c-ps MGI:MGI:3527440 +435206 Taar7d MGI:MGI:3527443|Ensembl:ENSMUSG00000095569|Vega:OTTMUSG00000019220 +435207 Taar7f MGI:MGI:3527447|Ensembl:ENSMUSG00000100950|Vega:OTTMUSG00000019222 +435208 Gm5649 MGI:MGI:3643590 +435235 Gm5650 MGI:MGI:3646505 +435256 Rpl9-ps2 MGI:MGI:3651724 +435270 Gm11424 MGI:MGI:3651336 +435271 Gm11427 MGI:MGI:3651774 +435273 Krtap1-3 MGI:MGI:3650443|Ensembl:ENSMUSG00000078131|Vega:OTTMUSG00000004964 +435285 Krtap4-16 MGI:MGI:3651030|Ensembl:ENSMUSG00000046474|Vega:OTTMUSG00000002196 +435286 Krtap9-5 MGI:MGI:3650333|Ensembl:ENSMUSG00000078255|Vega:OTTMUSG00000002205 +435292 Gm5652 MGI:MGI:3647692 +435302 Gm5653 MGI:MGI:3779508 +435309 Gm5654 MGI:MGI:3645051 +435314 Gm5655 MGI:MGI:3648022 +435316 Gm5656 MGI:MGI:3648024 +435318 Serpina3d-ps MGI:MGI:2182836 +435321 Ighv12-3 MGI:MGI:3646760|IMGT/GENE-DB:IGHV12-3 +435328 Ighv1-67 MGI:MGI:3645228|IMGT/GENE-DB:IGHV1-67 +435329 Gm5660 MGI:MGI:3644129 +435331 Ighv1-79 MGI:MGI:3648258|IMGT/GENE-DB:IGHV1-79 +435333 LOC435333 - +435337 Gm5662 MGI:MGI:3648257|Ensembl:ENSMUSG00000079029|Vega:OTTMUSG00000033111 +435350 Serpinb6e MGI:MGI:2667778|Ensembl:ENSMUSG00000069248|Vega:OTTMUSG00000000720 +435361 Rpl13-ps2 MGI:MGI:3645614 +435362 Gm5664 MGI:MGI:3645615 +435366 Platr25 MGI:MGI:3645613 +435373 Gm5666 MGI:MGI:3648664 +435375 Gm5667 MGI:MGI:3648667 +435376 Atp6ap1l MGI:MGI:3648665|Ensembl:ENSMUSG00000078958|Vega:OTTMUSG00000043582 +435378 Gm5668 MGI:MGI:3648669 +435389 Rpl31-ps3 MGI:MGI:3644189 +435391 Dupd1 MGI:MGI:3647127|Ensembl:ENSMUSG00000063821 +435392 Gm5670 MGI:MGI:3647128 +435420 Gm5671 MGI:MGI:3646581 +435422 Gm5672 MGI:MGI:3779510 +435442 Gm5673 MGI:MGI:3645950 +435480 Gm5674 MGI:MGI:3779511 +435483 Gm5675 MGI:MGI:3645539 +435484 Gm5676 MGI:MGI:3645537 +435486 Rpl31-ps4 MGI:MGI:3649126 +435489 Gm5678 MGI:MGI:3646098 +435499 Gm5679 MGI:MGI:3779512 +435509 Gm5681 MGI:MGI:3647870 +435518 Pdxk-ps MGI:MGI:1933201|Ensembl:ENSMUSG00000002791 +435525 Gm5682 MGI:MGI:3647684 +435528 Glyatl3 MGI:MGI:3647683|Ensembl:ENSMUSG00000091043 +435529 Adgrf2 MGI:MGI:2182728|Ensembl:ENSMUSG00000057899|Vega:OTTMUSG00000032803 +435531 Gm5684 MGI:MGI:3644507 +435549 Rpl7a-ps6 MGI:MGI:3647465 +435554 Gm5686 MGI:MGI:3644275 +435556 Gm5687 MGI:MGI:3644274 +435558 Gm5688 MGI:MGI:3644279 +435561 Gm5689 MGI:MGI:3647214 +435565 Iigp1b MGI:MGI:4366520 +435570 Gm5690 MGI:MGI:3644035 +435580 Gm5691 MGI:MGI:3646970 +435588 Gm5692 MGI:MGI:3646968 +435599 Gm5693 MGI:MGI:3643821 +435608 Gm5694 MGI:MGI:3645764 +435612 Gm5696 MGI:MGI:3647717 +435614 Gm5697 MGI:MGI:3649021 +435615 Gm5698 MGI:MGI:3649020 +435616 Gm5699 MGI:MGI:3648192 +435619 Gm5700 MGI:MGI:3649023 +435626 Rufy4 MGI:MGI:3588214|Ensembl:ENSMUSG00000061815|Vega:OTTMUSG00000026659 +435640 Gm5702 MGI:MGI:3646157 +435647 Gm5703 MGI:MGI:3646159 +435650 Gm5704 MGI:MGI:3643225 +435651 Gm5705 MGI:MGI:3643224 +435653 Fcrlb MGI:MGI:3576487|Ensembl:ENSMUSG00000070524|Vega:OTTMUSG00000049943 +435657 Gm5706 MGI:MGI:3643223 +435666 Gm13508 MGI:MGI:3649638 +435676 Gm13761 MGI:MGI:3651274 +435684 Shf MGI:MGI:3613669|Ensembl:ENSMUSG00000033256|Vega:OTTMUSG00000015613 +435692 Gm14214 MGI:MGI:3649357 +435727 Gm5708 MGI:MGI:3647478 +435732 Gm5709 MGI:MGI:3644280 +435743 Aqp10-ps MGI:MGI:4356425 +435752 Gm5710 MGI:MGI:3643595 +435753 Gm5711 MGI:MGI:3643596 +435755 Pou5f1-rs4 MGI:MGI:101889|Ensembl:ENSMUSG00000105712 +435761 Rpl9-ps8 MGI:MGI:3646987 +435766 Tnni3k MGI:MGI:2443276|Ensembl:ENSMUSG00000040086|Vega:OTTMUSG00000025997 +435772 Cnbd1 MGI:MGI:3650508 +435775 Gm12385 MGI:MGI:3651224 +435781 Gm12422 MGI:MGI:3651148 +435784 Rps15a-ps8 MGI:MGI:3652112 +435785 Mup-ps23 MGI:MGI:3650815 +435786 Gm11212 MGI:MGI:3651243 +435787 Rpl17-ps4 MGI:MGI:3651043 +435791 Gm13271 MGI:MGI:3701966|Ensembl:ENSMUSG00000094618|Vega:OTTMUSG00000011262 +435792 Gm12634 MGI:MGI:3650769 +435802 Cyp4a30b MGI:MGI:3717145|Ensembl:ENSMUSG00000084346|Vega:OTTMUSG00000008626 +435804 Olfr1335 MGI:MGI:3031168|Ensembl:ENSMUSG00000066061|Vega:OTTMUSG00000008768 +435811 Ldlrad2 MGI:MGI:3588210|Ensembl:ENSMUSG00000094035 +435815 Aadacl4 MGI:MGI:3650257|Ensembl:ENSMUSG00000070609|Vega:OTTMUSG00000010747 +435818 Slc2a7 MGI:MGI:3650865|Ensembl:ENSMUSG00000062064|Vega:OTTMUSG00000010396 +435830 Gm5714 MGI:MGI:3645857 +435832 Gm5715 MGI:MGI:3645858 +435845 Tmprss11c MGI:MGI:3521861|Ensembl:ENSMUSG00000061184|Vega:OTTMUSG00000024267 +435848 Gm5717 MGI:MGI:3649128 +435864 Vmn2r9 MGI:MGI:3643093|Ensembl:ENSMUSG00000091624|Vega:OTTMUSG00000039853 +435877 Vmn2r-ps25 MGI:MGI:3761470 +435881 Gm5721 MGI:MGI:3647813 +435900 Igkv12-98 MGI:MGI:4439560|IMGT/GENE-DB:IGKV12-98 +435904 Igkv12-40 MGI:MGI:3643951|IMGT/GENE-DB:IGKV12-40 +435912 Gm5723 MGI:MGI:3647796 +435916 Vmn2r23 MGI:MGI:3646826|Ensembl:ENSMUSG00000091620|Vega:OTTMUSG00000040030 +435921 Clec2f MGI:MGI:3522133 +435927 Gm5724 MGI:MGI:3643685|Ensembl:ENSMUSG00000084927|Vega:OTTMUSG00000033792 +435940 Gm5725 MGI:MGI:3644396|Ensembl:ENSMUSG00000095191|Vega:OTTMUSG00000038115 +435946 Gm5726 MGI:MGI:3644395|Ensembl:ENSMUSG00000096761|Vega:OTTMUSG00000038198 +435947 Vmn1r151 MGI:MGI:3644394|Ensembl:ENSMUSG00000093853|Vega:OTTMUSG00000038059 +435949 Gm5728 MGI:MGI:3644398|Ensembl:ENSMUSG00000095806|Vega:OTTMUSG00000038192 +435951 Vmn1r122 MGI:MGI:3647341|Ensembl:ENSMUSG00000094001|Vega:OTTMUSG00000038159 +435953 Vmn1r120 MGI:MGI:3647340|Ensembl:ENSMUSG00000093986|Vega:OTTMUSG00000038156 +435962 Gm5731 MGI:MGI:3644173 +435963 Gm5732 MGI:MGI:3644172 +435965 Lrp3 MGI:MGI:3584516|Ensembl:ENSMUSG00000001802|Vega:OTTMUSG00000027211 +435975 Vmn2r63 MGI:MGI:3647107|Ensembl:ENSMUSG00000090751|Vega:OTTMUSG00000037914 +435977 Gm5733 MGI:MGI:3642992 +435978 Gm5734 MGI:MGI:3647104 +435996 Gm5735 MGI:MGI:3645951 +436002 Olfr243 MGI:MGI:3030077|Ensembl:ENSMUSG00000094822|Vega:OTTMUSG00000019088 +436003 Hbb-bh2 MGI:MGI:96025|Ensembl:ENSMUSG00000078621|Vega:OTTMUSG00000019093 +436008 Gm5737 MGI:MGI:3645276 +436010 Gm5738 MGI:MGI:3648290 +436015 B130016D09Rik MGI:MGI:3642866 +436022 Dnaaf3 MGI:MGI:3588207|Ensembl:ENSMUSG00000055809|Vega:OTTMUSG00000027090 +436026 Gm5739 MGI:MGI:3645094 +436033 Gm16205 MGI:MGI:3801883 +436042 Gm5740 MGI:MGI:3645689 +436054 Gm5742 MGI:MGI:3648738 +436058 Gm5743 MGI:MGI:3648739 +436059 Ces2h MGI:MGI:3648740|Ensembl:ENSMUSG00000091813|Vega:OTTMUSG00000061991 +436062 Fam92b MGI:MGI:3588213|Ensembl:ENSMUSG00000042269|Vega:OTTMUSG00000027533 +436081 Gm5745 MGI:MGI:3645343 +436082 Gm5746 MGI:MGI:3645350 +436085 Gm5747 MGI:MGI:3779513 +436090 Gpr62 MGI:MGI:3525078|Ensembl:ENSMUSG00000091735|Vega:OTTMUSG00000049535 +436100 Gm21814 MGI:MGI:5433978 +436135 Vmn1r113 MGI:MGI:3647303|Ensembl:ENSMUSG00000091638|Vega:OTTMUSG00000038148 +436137 Gm5749 MGI:MGI:3647304 +436146 Gm13104 MGI:MGI:3650202 +436164 Gm5750 MGI:MGI:3644575 +436185 Gm14452 MGI:MGI:3651429 +436188 Gm5751 MGI:MGI:3642927 +436189 Gm5752 MGI:MGI:3642928 +436190 Gm14457 MGI:MGI:3650389 +436193 Fthl17-ps3 MGI:MGI:3643671 +436194 Gm5754 MGI:MGI:3646109 +436196 Gm5755 MGI:MGI:3646107 +436198 Rhox7b MGI:MGI:3705218 +436199 Btg1-ps1 MGI:MGI:3588262|Ensembl:ENSMUSG00000068173 +436208 Gm5757 MGI:MGI:3644663 +436212 Mageb8-ps MGI:MGI:2148172 +436213 Gm5759 MGI:MGI:3647657 +436219 Gm5760 MGI:MGI:3647653 +436230 BC065397 MGI:MGI:3584520|Ensembl:ENSMUSG00000087368 +436231 Gm5761 MGI:MGI:3647843 +436232 Gm15041 MGI:MGI:3647842 +436234 Gm5762 MGI:MGI:3647840 +436235 Gm5763 MGI:MGI:3647841 +436240 Foxr2 MGI:MGI:3511682|Ensembl:ENSMUSG00000071665|Vega:OTTMUSG00000019338 +436243 Gm5764 MGI:MGI:3645102 +436332 Gm5766 MGI:MGI:3643508|Ensembl:ENSMUSG00000089645 +436336 Gm5767 MGI:MGI:3643507 +436405 Gm5768 MGI:MGI:3647546 +436421 Gm5769 MGI:MGI:3647280 +436440 Gpr31b MGI:MGI:1354372|Ensembl:ENSMUSG00000071311 +436467 Trav14-1 MGI:MGI:3646773 +436468 Trav15d-1-dv6d-1 MGI:MGI:3651288|IMGT/GENE-DB:TRAV15D-1/DV6D-1 +436479 Trav9-2 MGI:MGI:4439903|IMGT/GENE-DB:TRAV9-2 +436522 Try10 MGI:MGI:3687012|Ensembl:ENSMUSG00000071521|Vega:OTTMUSG00000051419 +436523 Gm5771 MGI:MGI:3646222|Ensembl:ENSMUSG00000058119|Vega:OTTMUSG00000051421 +436539 Trav6-2 MGI:MGI:3642602|IMGT/GENE-DB:TRAV6-2 +436545 Trav15-2-dv6-2 MGI:MGI:3702147|IMGT/GENE-DB:TRAV15-2/DV6-2 +436563 Gm5773 MGI:MGI:3645792 +436576 M-01983 MGI:MGI:2153490 +436579 D5Mit286 MGI:MGI:100430 +436583 Snora74a MGI:MGI:3646921|Ensembl:ENSMUSG00000065649 +442794 D3Tem3 MGI:MGI:1197016 +442795 E130018O15Rik MGI:MGI:3045238|Ensembl:ENSMUSG00000055944 +442796 A230052G05Rik MGI:MGI:3045239|Ensembl:ENSMUSG00000020887 +442797 6330444E15Rik MGI:MGI:3045241 +442798 9630041A04Rik MGI:MGI:3045242 +442799 9330154J02Rik MGI:MGI:3045244 +442800 D430018E03Rik MGI:MGI:3045245 +442801 Arhgef15 MGI:MGI:3045246|Ensembl:ENSMUSG00000052921|Vega:OTTMUSG00000005952 +442802 C330011M18Rik MGI:MGI:3045248 +442803 A830005F24Rik MGI:MGI:3045249|Ensembl:ENSMUSG00000053181|Vega:OTTMUSG00000042087 +442804 Kirrel3os MGI:MGI:3045250 +442805 D130007C19Rik MGI:MGI:3045257 +442806 E330033J05Rik MGI:MGI:3045262 +442807 D630036G22Rik MGI:MGI:3045265 +442808 A330032P22Rik MGI:MGI:3045270 +442809 4932416K20Rik MGI:MGI:3045271 +442810 A130023E24Rik MGI:MGI:3045272 +442811 9030223M17Rik MGI:MGI:3045273 +442812 B930049P21Rik MGI:MGI:3045275 +442813 9430025C20Rik MGI:MGI:3045277 +442814 5031438A03Rik MGI:MGI:3045278 +442815 A230065C20Rik MGI:MGI:3045279 +442816 F830005K03Rik MGI:MGI:3045280 +442817 C130046B21Rik MGI:MGI:3045281 +442818 9430025E04Rik MGI:MGI:3045282 +442819 F830031D20Rik MGI:MGI:3045283 +442820 D830005E20Rik MGI:MGI:3045284|Ensembl:ENSMUSG00000112707 +442821 9330175M20Rik MGI:MGI:3045285|Ensembl:ENSMUSG00000101799 +442822 9530085L02Rik MGI:MGI:3045286 +442823 A230085B16Rik MGI:MGI:3045287 +442824 G630030J09Rik MGI:MGI:3045288 +442825 A230083G16Rik MGI:MGI:3045289|Ensembl:ENSMUSG00000055818 +442826 A930006L05Rik MGI:MGI:3045290 +442827 Rab44 MGI:MGI:3045302|Ensembl:ENSMUSG00000064147|Vega:OTTMUSG00000031657 +442829 Ccin MGI:MGI:3045316|Ensembl:ENSMUSG00000070999|Vega:OTTMUSG00000007205 +442834 D830031N03Rik MGI:MGI:3045367 +442835 Defb22 MGI:MGI:3045368|Ensembl:ENSMUSG00000027468|Vega:OTTMUSG00000015853 +442836 A530053M12Rik MGI:MGI:3045369 +442837 C230029F24Rik MGI:MGI:3045370|Ensembl:ENSMUSG00000051616 +442838 A830021F12Rik MGI:MGI:3045372 +442840 A330017A19Rik MGI:MGI:3045380 +442842 A830035A12Rik MGI:MGI:3045382 +442845 F730035P03Rik MGI:MGI:3045385 +442846 A530050N04Rik MGI:MGI:3045386 +442847 Platr7 MGI:MGI:3045387|Ensembl:ENSMUSG00000097076 +442848 E230014E18Rik MGI:MGI:3045388 +442849 C330019F10Rik MGI:MGI:3045389 +442851 D3Tem2 MGI:MGI:1197017 +442852 D6Tem2 MGI:MGI:1197021 +442853 D6Tem3 MGI:MGI:1197022 +442854 D6Tem1 MGI:MGI:1197023 +442855 D6Tem4 MGI:MGI:1197025 +443553 D6Rp3 MGI:MGI:109409 +445007 Nup85 MGI:MGI:3046173|Ensembl:ENSMUSG00000020739|Vega:OTTMUSG00000003479 +445261 Dnmt3a-ps1 MGI:MGI:2674154 +445264 Dnmt3l-ps1 MGI:MGI:2674156 +445267 Nphs1os MGI:MGI:2675468|Ensembl:ENSMUSG00000087009 +446099 Nlrp4e MGI:MGI:3056600|Ensembl:ENSMUSG00000045693|Vega:OTTMUSG00000027236 +446100 Vhl-ps1 MGI:MGI:3051121 +446101 Xrra1 MGI:MGI:2181647|Ensembl:ENSMUSG00000035211|Vega:OTTMUSG00000059072 +446210 AY702103 MGI:MGI:3525105|Ensembl:ENSMUSG00000067103 +446211 AY702102 MGI:MGI:3525150|Ensembl:ENSMUSG00000103935 +446215 Nanog-ps1 MGI:MGI:3051568 +446216 Nanog-ps2 MGI:MGI:3051570 +448829 Anp32-ps MGI:MGI:3525200 +448850 Znhit3 MGI:MGI:3051596|Ensembl:ENSMUSG00000020526|Vega:OTTMUSG00000001020 +448986 Pnet-ps MGI:MGI:3052454 +448987 Fbxl7 MGI:MGI:3052506|Ensembl:ENSMUSG00000043556 +449000 Zfp960 MGI:MGI:3052731|Ensembl:ENSMUSG00000096696|Vega:OTTMUSG00000033428 +449521 Zfp213 MGI:MGI:3053094|Ensembl:ENSMUSG00000071256 +449522 E130314M14Rik MGI:MGI:3053211 +449561 AF357426 MGI:MGI:3053433 +449562 AF357425 MGI:MGI:3053434|Ensembl:ENSMUSG00000088294 +449563 AF357428 MGI:MGI:3053436 +449630 Snord15a MGI:MGI:3645887|Ensembl:ENSMUSG00000065822 +449631 Snord15b MGI:MGI:3779515|Ensembl:ENSMUSG00000064966 +450219 Gsdma3 MGI:MGI:3044668|Ensembl:ENSMUSG00000064224|Vega:OTTMUSG00000006394 +474145 Clec4a4 MGI:MGI:3624119|Ensembl:ENSMUSG00000059639|Vega:OTTMUSG00000027035 +474156 Zbtb9 MGI:MGI:1918022|Ensembl:ENSMUSG00000079605|Vega:OTTMUSG00000031000 +474160 Platr17 MGI:MGI:3054967|Ensembl:ENSMUSG00000092349 +474332 Dnm3os MGI:MGI:3052332|Ensembl:ENSMUSG00000078190 +492824 Ath11 MGI:MGI:1890352 +492825 Ath13 MGI:MGI:1890354 +492826 Ath16 MGI:MGI:2137649 +492827 Babr MGI:MGI:2177437 +492828 Bmd10 MGI:MGI:2389096 +492829 Bmd11 MGI:MGI:2389097 +492830 Bmd12 MGI:MGI:2389098 +492831 Bmd13 MGI:MGI:2389099 +492832 Bmd14 MGI:MGI:2389101 +492833 Bmd15 MGI:MGI:2389102 +492834 Bmd5 MGI:MGI:2389129 +492835 Bmd6 MGI:MGI:2389130 +492836 Bmd7 MGI:MGI:2389131 +492837 Bmd8 MGI:MGI:2389093 +492838 Bmd9 MGI:MGI:2389094 +492839 Cdcs10 MGI:MGI:2159145 +492840 Cdcs7 MGI:MGI:2159142 +492841 Elnt MGI:MGI:2387316 +492842 Hrec MGI:MGI:2387295 +492843 Hrtfm1 MGI:MGI:2389057 +492844 Nctm1 MGI:MGI:2451367 +492845 Odsm1 MGI:MGI:2653281 +492846 Otx2m2 MGI:MGI:2445327 +492847 Pbbcp1 MGI:MGI:1930819 +492848 Pidys MGI:MGI:2386641 +492849 Sbnt2 MGI:MGI:2387318 +492850 Sluc15 MGI:MGI:2387359 +492851 Sluc16 MGI:MGI:2387360 +492852 Sluc17 MGI:MGI:2387361 +492853 Sluc19 MGI:MGI:2387363 +492854 Sluc20 MGI:MGI:2387364 +492855 Sluc21 MGI:MGI:2387365 +492856 Sluc22 MGI:MGI:2387366 +492857 Sluc23 MGI:MGI:2387368 +492858 Sluc24 MGI:MGI:2387369 +492859 Sluc28 MGI:MGI:2387373 +492860 Sluc29 MGI:MGI:2387374 +492861 Sluc30 MGI:MGI:2387375 +492862 Rear1 MGI:MGI:2680096 +492863 Rear2 MGI:MGI:2680097 +492864 Eila1 MGI:MGI:2680927 +492865 Eila2 MGI:MGI:2680928 +492866 Eila3 MGI:MGI:2680929 +492867 Bmd19 MGI:MGI:2681004 +492868 Acsns2 MGI:MGI:2389043 +492869 Acsns3 MGI:MGI:2389044 +492870 Aod1a MGI:MGI:2664517 +492871 Aod1b MGI:MGI:2664518 +492872 Aod4 MGI:MGI:2670443 +492873 Aod5 MGI:MGI:2670444 +492874 Arrd1 MGI:MGI:2664137 +492876 Arrd3 MGI:MGI:2664139 +492877 Asbb3 MGI:MGI:2389190 +492878 Berr1 MGI:MGI:2669988 +492879 Berr2 MGI:MGI:2669990 +492880 Blmpf1 MGI:MGI:2668887 +492881 Blmpf2 MGI:MGI:2668888 +492882 Cd4ts1 MGI:MGI:2661245 +492883 Cd4ts2 MGI:MGI:2661254 +492884 Cd4ts3 MGI:MGI:2661274 +492885 Cd4ts4 MGI:MGI:2661276 +492886 Cd4ts5 MGI:MGI:2661278 +492887 Cd4ts6 MGI:MGI:2661280 +492888 Cd4vts1 MGI:MGI:2661256 +492889 Cd8mts1 MGI:MGI:2661242 +492890 Cd8mts3 MGI:MGI:2661248 +492891 Cd8mts4 MGI:MGI:2661277 +492892 Cd8mts5 MGI:MGI:2661283 +492893 Cd8mts6 MGI:MGI:2661284 +492894 Egrd1 MGI:MGI:2662751 +492895 Egrd2 MGI:MGI:2662754 +492896 Egrm1 MGI:MGI:2662757 +492897 Egrm2 MGI:MGI:2662761 +492898 Fembrs5 MGI:MGI:1891230 +492899 Fembrs6 MGI:MGI:2386571 +492900 Fglu2 MGI:MGI:2660561 +492901 Fpli MGI:MGI:2660570 +492902 Hbnr3 MGI:MGI:2660592 +492903 Lmr9 MGI:MGI:2656542 +492904 Ltsd2 MGI:MGI:2664839 +492905 Ltsd4 MGI:MGI:2664841 +492906 Mbis1 MGI:MGI:2669461 +492907 Mbis2 MGI:MGI:2669462 +492908 Mnic2 MGI:MGI:2151836 +492909 Mnif1 MGI:MGI:2151834 +492910 Mprf MGI:MGI:2661774 +492911 Mptp1 MGI:MGI:2656753 +492912 Nidd2k MGI:MGI:2387103 +492913 Nidd3k MGI:MGI:2387104 +492914 Nidd4k MGI:MGI:2387105 +492915 Nociq2 MGI:MGI:2388670 +492916 Opfa MGI:MGI:2669474 +492917 Pcd4ts1 MGI:MGI:2661273 +492918 Pcd8ts1 MGI:MGI:2661259 +492919 Pcfm2 MGI:MGI:2670130 +492920 Pcfm3 MGI:MGI:2670131 +492921 Pcfm4 MGI:MGI:2670132 +492922 Pcir1 MGI:MGI:2670124 +492923 Ssial1 MGI:MGI:2385531 +492924 Ssial3 MGI:MGI:2385533 +492925 Ssta1 MGI:MGI:2661144 +492926 Ssta2 MGI:MGI:2661145 +492927 Ssta3 MGI:MGI:2661146 +492928 Tmevd6 MGI:MGI:2669608 +492929 Tmevd7 MGI:MGI:2669609 +492930 Tshp4 MGI:MGI:2386694 +492931 Tshp5 MGI:MGI:2386695 +492932 Tshp6 MGI:MGI:2386696 +492933 Tshp7 MGI:MGI:2386697 +492934 Tshp8 MGI:MGI:2386698 +492935 Vent1 MGI:MGI:2664089 +492936 Bslm4 MGI:MGI:2682357 +492937 Hycdc MGI:MGI:2682394 +492938 Hypt MGI:MGI:2682418 +492939 Angvq1 MGI:MGI:2683513 +492940 Idd21 MGI:MGI:2684594 +492941 Trigq1 MGI:MGI:3029249 +492942 Modc1 MGI:MGI:2154197 +492943 Prnr2 MGI:MGI:3042571 +492944 Aibl MGI:MGI:3045753 +492945 Alaa2 MGI:MGI:2677751 +492946 Alaa3 MGI:MGI:2677752 +492947 Alcdp1 MGI:MGI:3050452 +492948 Alcrsp1 MGI:MGI:3053618 +492949 Alcrsp2 MGI:MGI:3053619 +492950 Alcrsp4 MGI:MGI:3053622 +492951 Chol7 MGI:MGI:2653463 +492952 Cocia10 MGI:MGI:3040201 +492953 Cocia4 MGI:MGI:3040195 +492954 Cocia5 MGI:MGI:3040196 +492955 Cocia6 MGI:MGI:3040197 +492956 Cocia7 MGI:MGI:3040198 +492957 Cocia8 MGI:MGI:3040199 +492958 Cocia9 MGI:MGI:3040200 +492959 Epfq1 MGI:MGI:3042892 +492960 Epfq5 MGI:MGI:3042907 +492961 Gcsfis MGI:MGI:3046813 +492962 Grv MGI:MGI:3052078 +492963 Hcif2 MGI:MGI:3046664 +492964 Hdl5 MGI:MGI:3036902 +492965 Hdlq14 MGI:MGI:2448347 +492966 Hdlq15 MGI:MGI:2448348 +492967 Hdlq16 MGI:MGI:2653462 +492968 Hdlq19 MGI:MGI:2679571 +492969 Hdlq20 MGI:MGI:2679572 +492970 Hdlq21 MGI:MGI:3041283 +492971 Hdlq22 MGI:MGI:3041284 +492972 Hdlq24 MGI:MGI:3041286 +492973 Hdlq25 MGI:MGI:3041287 +492974 Hdlq6 MGI:MGI:2448339 +492975 Hrtpq1 MGI:MGI:3042898 +492976 Hrtq1 MGI:MGI:3043439 +492977 Hrtq2 MGI:MGI:3042889 +492978 Idd22 MGI:MGI:2683518 +492979 Igf1sl1 MGI:MGI:3046873 +492980 Im3 MGI:MGI:3032849 +492981 Im4 MGI:MGI:3032855 +492982 Kidq2 MGI:MGI:3042878 +492983 Kidq3 MGI:MGI:3042885 +492984 Kidq4 MGI:MGI:3042901 +492985 Kidq5 MGI:MGI:3042904 +492986 Kidq6 MGI:MGI:3042908 +492987 Kidq7 MGI:MGI:3042899 +492988 Lmblgq3 MGI:MGI:3042421 +492989 Lnopy1 MGI:MGI:3052174 +492990 Lrdg1 MGI:MGI:3042607 +492991 Lscc1 MGI:MGI:3040189 +492992 Lscc2 MGI:MGI:3040190 +492993 Lvic1 MGI:MGI:3036609 +492994 Lvic2 MGI:MGI:3036610 +492995 Lvic3 MGI:MGI:3036611 +492996 Lvrq1 MGI:MGI:3042875 +492997 Lvrq3 MGI:MGI:3042883 +492998 Lvrq5 MGI:MGI:3042896 +492999 Lvrq6 MGI:MGI:3042906 +493000 Lvrq8 MGI:MGI:3042902 +493001 Lvrq9 MGI:MGI:3042900 +493002 Nidd7k MGI:MGI:3038862 +493003 Nrtim1 MGI:MGI:3053621 +493004 Orgwq1 MGI:MGI:3042410 +493005 Orgwq2 MGI:MGI:3042411 +493006 Orgwq3 MGI:MGI:3042412 +493007 Orgwq4 MGI:MGI:3042413 +493008 Orgwq5 MGI:MGI:3042414 +493009 Orgwq6 MGI:MGI:3042415 +493010 Orgwq7 MGI:MGI:3042416 +493011 Pbwg11 MGI:MGI:3035969 +493012 Pbwg13 MGI:MGI:3035971 +493013 Pbwg3 MGI:MGI:3035959 +493014 Si5lq3 MGI:MGI:3047363 +493015 Skmw2 MGI:MGI:3036183 +493016 Smdq1 MGI:MGI:2179702 +493017 Smdq2 MGI:MGI:2179703 +493018 Splq1 MGI:MGI:3042882 +493019 Tsvw1 MGI:MGI:3044630 +493020 Tlyr1 MGI:MGI:2651474 +493021 Tnbs2 MGI:MGI:2451076 +493022 Dloc1 MGI:MGI:2680099 +493023 Dloc2 MGI:MGI:2680100 +493024 Hdis MGI:MGI:2680101 +493025 Nktcn1 MGI:MGI:2681136 +493026 Nktcn2 MGI:MGI:2681137 +493027 Dpml MGI:MGI:2681143 +493028 Bw8q1 MGI:MGI:2681283 +493029 Bw8q2 MGI:MGI:2681284 +493030 Lith12 MGI:MGI:2653457 +493031 Lith13 MGI:MGI:2653459 +493032 Lith14 MGI:MGI:2653460 +493033 Lith6 MGI:MGI:2653451 +493034 Lith10 MGI:MGI:2653455 +493035 Pgia29 MGI:MGI:2675281 +493036 Ahl2 MGI:MGI:1890802 +493037 Cd8ts1 MGI:MGI:2661257 +493038 Cd8ts2 MGI:MGI:2661275 +493039 Cd8ts3 MGI:MGI:2661281 +493040 Cfbw2 MGI:MGI:2661704 +493041 Cfbw3 MGI:MGI:2661705 +493042 Cfbw5 MGI:MGI:2661707 +493043 Cfld2 MGI:MGI:2661732 +493044 Cfld3 MGI:MGI:2661734 +493045 Cia15 MGI:MGI:2656532 +493046 Cia20 MGI:MGI:2656538 +493047 Circp1 MGI:MGI:2661438 +493048 Derms MGI:MGI:2669279 +493049 Etoms MGI:MGI:2663494 +493050 Fcsa4 MGI:MGI:2668938 +493051 Fcsa6 MGI:MGI:2668940 +493052 Fcsa7 MGI:MGI:2668941 +493053 Fembrs1 MGI:MGI:2386565 +493054 Fembrs2 MGI:MGI:2386566 +493055 Fembrs3 MGI:MGI:2386567 +493056 Gauc MGI:MGI:2660571 +493057 Hdlq4 MGI:MGI:2387137 +493058 Heal10 MGI:MGI:2669605 +493059 Heal11 MGI:MGI:2669606 +493060 Hbnr1 MGI:MGI:2660589 +493061 Hsl1 MGI:MGI:2389119 +493062 Ksc1 MGI:MGI:2668899 +493063 Ksc2 MGI:MGI:2668900 +493064 Lbm1 MGI:MGI:2656802 +493065 Lbm2 MGI:MGI:2656803 +493066 Lbm3 MGI:MGI:2656804 +493067 Lbm4 MGI:MGI:2656805 +493068 Lgth1 MGI:MGI:2656812 +493069 Lgth2 MGI:MGI:2656813 +493070 Lgth3 MGI:MGI:2656814 +493071 Lgth5 MGI:MGI:2656816 +493072 Lith7 MGI:MGI:2653452 +493073 Lith8 MGI:MGI:2653453 +493074 Lmr10 MGI:MGI:2656543 +493075 Lmr11 MGI:MGI:2656544 +493076 Lmr14 MGI:MGI:2656547 +493077 Lmr15 MGI:MGI:2656607 +493078 Lmr3 MGI:MGI:2656514 +493079 Lmr8 MGI:MGI:2656541 +493080 Pcyts2 MGI:MGI:2665063 +493081 Pgia19 MGI:MGI:2656521 +493082 Radpf2 MGI:MGI:2155287 +493083 Scon2 MGI:MGI:2661414 +493084 Ses2 MGI:MGI:2664974 +493085 Susp MGI:MGI:2152196 +493086 Sysbp1 MGI:MGI:2684016 +493087 Sysbp2 MGI:MGI:2684017 +493088 Pltpq2 MGI:MGI:2684019 +493089 Pltpq4 MGI:MGI:2684021 +493090 Pltiq1 MGI:MGI:2684022 +493091 Anxty MGI:MGI:2686944 +493092 Hrtfm6 MGI:MGI:2686943 +493093 Abbp4 MGI:MGI:3026894 +493094 Chol10 MGI:MGI:3029247 +493095 Chol11 MGI:MGI:3029248 +493096 Trigq2 MGI:MGI:3029252 +493097 Lipq1 MGI:MGI:2662492 +493098 Lipq2 MGI:MGI:2662493 +493099 Lipq3 MGI:MGI:2662494 +493100 Fbgl1 MGI:MGI:3038476 +493101 Tgl1 MGI:MGI:3038479 +493102 Fdpref MGI:MGI:3038619 +493103 Dntcs1 MGI:MGI:3040351 +493104 Dntcs2 MGI:MGI:3040352 +493105 Tswt MGI:MGI:3040365 +493106 Spha2 MGI:MGI:3040363 +493107 Hdlq17 MGI:MGI:2656139 +493108 Hdlq18 MGI:MGI:2656140 +493109 Nhdlq3 MGI:MGI:3041084 +493110 Bpq8 MGI:MGI:1891320 +493111 Bpq9 MGI:MGI:2681406 +493112 Thyls2 MGI:MGI:3042404 +493113 Lrdg2 MGI:MGI:3042608 +493114 Prnr1 MGI:MGI:3042570 +493115 Alcw5 MGI:MGI:3037038 +493116 Angfq1 MGI:MGI:3046555 +493117 Angfq3 MGI:MGI:3046557 +493118 Aorls2 MGI:MGI:3036905 +493119 Bsbob MGI:MGI:3045759 +493120 Bsbob2 MGI:MGI:3051758 +493121 Bsbob3 MGI:MGI:3051759 +493122 Char5 MGI:MGI:3043794 +493123 Char6 MGI:MGI:3043795 +493124 Ctrcts MGI:MGI:3052176 +493125 Dmyaq1 MGI:MGI:3051263 +493126 Dmyaq2 MGI:MGI:3051264 +493127 Elsgp1 MGI:MGI:3040461 +493128 Epfpq2 MGI:MGI:3042884 +493129 Hdlq7 MGI:MGI:2448340 +493131 Hivan1 MGI:MGI:3037874 +493132 Hpcr1 MGI:MGI:3046736 +493133 Hpdty MGI:MGI:3043724 +493134 Lvrq2 MGI:MGI:3042887 +493135 Lxw1 MGI:MGI:3036207 +493136 Lxw2 MGI:MGI:3036208 +493137 Lxw3 MGI:MGI:3036323 +493138 Lxw4 MGI:MGI:3036324 +493139 Lxw5 MGI:MGI:3036325 +493140 Lxw6 MGI:MGI:3036326 +493141 Marif1 MGI:MGI:2677755 +493142 Marif2 MGI:MGI:2677756 +493143 Mdmsc1 MGI:MGI:3054065 +493144 Mdmsc2 MGI:MGI:3054066 +493145 Mdmsc3 MGI:MGI:3054067 +493146 Mnotch MGI:MGI:2684308 +493147 msrvh1 MGI:MGI:3045789 +493148 Nhdlq1 MGI:MGI:2653466 +493149 Nidd5k MGI:MGI:3038860 +493150 Pbwg8 MGI:MGI:3035966 +493151 Pfat1 MGI:MGI:3046213 +493152 Pfat2 MGI:MGI:3046214 +493153 Prxsh MGI:MGI:3043725 +493154 Scfq1 MGI:MGI:3042890 +493155 Schol MGI:MGI:3037875 +493156 Si5lq1 MGI:MGI:3047361 +493157 Si5lq2 MGI:MGI:3047362 +493158 Splq2 MGI:MGI:3042888 +493159 Splq3 MGI:MGI:3042876 +493160 Splq4 MGI:MGI:3042909 +493161 Splq5 MGI:MGI:3042880 +493162 Splq6 MGI:MGI:3042894 +493163 Splq7 MGI:MGI:3042905 +493164 Synch1 MGI:MGI:3052177 +493165 Synch2 MGI:MGI:3052178 +493166 Synch3 MGI:MGI:3052179 +493167 Tbdr1 MGI:MGI:2655235 +493168 Tesq2 MGI:MGI:3042903 +493169 Thyct2 MGI:MGI:3051295 +493170 Vmbic1 MGI:MGI:3036599 +493171 Vmbic2 MGI:MGI:3036600 +493172 Vmbic3 MGI:MGI:3036601 +493173 Vmbic5 MGI:MGI:3036603 +493174 Vpantd MGI:MGI:3043719 +493175 Vtbt1 MGI:MGI:3045043 +493176 Vtbt2 MGI:MGI:3045044 +493177 Vtbt3 MGI:MGI:3045045 +493178 Vtbt4 MGI:MGI:3045046 +493179 Vtbt7 MGI:MGI:3045049 +493180 Vtbt8 MGI:MGI:3045050 +493581 LOC493581 - +493583 Itlnb MGI:MGI:3057189 +493800 9330162012Rik MGI:MGI:3604449 +493809 Taar3 MGI:MGI:3527427|Ensembl:ENSMUSG00000069708|Vega:OTTMUSG00000019213 +493918 Fcnc-ps MGI:MGI:3510254 +493919 Snord115 MGI:MGI:3510326 +493920 AF357341 MGI:MGI:3510328 +494124 Calm5 MGI:MGI:3511177|Ensembl:ENSMUSG00000099269|Vega:OTTMUSG00000044356 +494218 Gm11359 MGI:MGI:3651591 +494448 Cbx6 MGI:MGI:3512628|Ensembl:ENSMUSG00000089715|Vega:OTTMUSG00000017454 +494468 Armcx5 MGI:MGI:2148026|Ensembl:ENSMUSG00000072969|Vega:OTTMUSG00000018771 +494497 BC037156 MGI:MGI:3512757 +494504 Apcdd1 MGI:MGI:3513977|Ensembl:ENSMUSG00000071847 +494519 Scgb2b20 MGI:MGI:3514009|Ensembl:ENSMUSG00000094305|Vega:OTTMUSG00000045850 +494546 Taar8c MGI:MGI:3527452|Ensembl:ENSMUSG00000100004|Vega:OTTMUSG00000019211 +497028 Gm5776 MGI:MGI:3647650 +497071 Rnase13 MGI:MGI:3528592|Ensembl:ENSMUSG00000068392 +497097 Xkr4 MGI:MGI:3528744|Ensembl:ENSMUSG00000051951|Vega:OTTMUSG00000026353 +497104 Ang-ps3 MGI:MGI:3528607 +497105 Ear-ps7 MGI:MGI:3528630 +497106 Rnase12 MGI:MGI:3528588|Ensembl:ENSMUSG00000068407 +497107 Ear-ps3 MGI:MGI:3528619 +497108 Ear-ps4 MGI:MGI:3528621 +497109 Ear-ps8 MGI:MGI:3528634 +497113 Rnase11 MGI:MGI:3528583|Ensembl:ENSMUSG00000059648|Vega:OTTMUSG00000043570 +497114 Defa23 MGI:MGI:3630381|Ensembl:ENSMUSG00000074446|Vega:OTTMUSG00000019488 +497118 Dcr3 - +497252 LOC497252 - +497254 LOC497254 - +497255 LOC497255 - +497266 LOC497266 - +497652 Acd MGI:MGI:87873|Ensembl:ENSMUSG00000038000|Vega:OTTMUSG00000062053 +497655 Gm11451 MGI:MGI:3705412 +503491 Defa24 MGI:MGI:3630383|Ensembl:ENSMUSG00000064213|Vega:OTTMUSG00000019980 +503493 Ear-ps9 MGI:MGI:3528636 +503495 Ear-ps10 MGI:MGI:3528640 +503550 Klri1 MGI:MGI:3530275|Ensembl:ENSMUSG00000067610|Vega:OTTMUSG00000032513 +503558 Taar9 MGI:MGI:3527454|Ensembl:ENSMUSG00000037424|Vega:OTTMUSG00000019224 +503610 Zdhhc18 MGI:MGI:3527792|Ensembl:ENSMUSG00000037553|Vega:OTTMUSG00000011205 +503688 AY339874 MGI:MGI:3528210 +503690 A930005G22Rik MGI:MGI:3528178 +503691 A030001O10Rik MGI:MGI:3528182 +503692 Aym1 MGI:MGI:1891321|Ensembl:ENSMUSG00000053873|Vega:OTTMUSG00000054495 +503844 Ang5 MGI:MGI:3528599|Ensembl:ENSMUSG00000053961|Vega:OTTMUSG00000034650 +503845 Ear12 MGI:MGI:3528610 +503847 Ear14 MGI:MGI:3528616|Ensembl:ENSMUSG00000050766 +503848 Ear-ps5 MGI:MGI:3528623 +503849 Ear-ps12 MGI:MGI:3528644 +503851 B930025B16Rik MGI:MGI:3528901 +504186 Chrna10 MGI:MGI:3609260|Ensembl:ENSMUSG00000066279|Vega:OTTMUSG00000061194 +504193 Npcd MGI:MGI:3845555|Ensembl:ENSMUSG00000089837|Vega:OTTMUSG00000017448 +541307 Ccl26 MGI:MGI:3589281|Ensembl:ENSMUSG00000070464|Vega:OTTMUSG00000055904 +541463 Tex24 MGI:MGI:1921539|Ensembl:ENSMUSG00000071138|Vega:OTTMUSG00000061034 +541610 Trcg1 MGI:MGI:3576664|Ensembl:ENSMUSG00000070298|Vega:OTTMUSG00000061751 +544678 Cfap74 MGI:MGI:1917130|Ensembl:ENSMUSG00000078490|Vega:OTTMUSG00000010614 +544696 Tbc1d32 MGI:MGI:2442827|Ensembl:ENSMUSG00000038122 +544698 Gm5777 MGI:MGI:3645433 +544705 Gm5778 MGI:MGI:3646275 +544707 Gm5779 MGI:MGI:3645934|Ensembl:ENSMUSG00000112471 +544710 Krtap10-10 MGI:MGI:3645300|Ensembl:ENSMUSG00000112223 +544716 Ap3m1-ps MGI:MGI:3645307 +544717 1190007I07Rik MGI:MGI:3698433|Ensembl:ENSMUSG00000063320|Vega:OTTMUSG00000040006 +544719 Gm5780 MGI:MGI:3645288 +544724 LOC544724 - +544736 Glipr1l3 MGI:MGI:3620621|Ensembl:ENSMUSG00000112611 +544737 Gm26596 MGI:MGI:5477090|Ensembl:ENSMUSG00000097185 +544741 Gm5781 MGI:MGI:3646721 +544748 Olfr765 MGI:MGI:3030599|Ensembl:ENSMUSG00000056853|Vega:OTTMUSG00000056477 +544749 Olfr779 MGI:MGI:3030613 +544752 Tug1 MGI:MGI:2144114|Ensembl:ENSMUSG00000056579 +544763 Hbq1b MGI:MGI:3613460|Ensembl:ENSMUSG00000073063|Vega:OTTMUSG00000005372 +544767 Gm5782 MGI:MGI:3646984 +544782 Gm12620 MGI:MGI:3649879 +544791 Myh13 MGI:MGI:1339967|Ensembl:ENSMUSG00000060180|Vega:OTTMUSG00000005927 +544792 Gsg1l2 MGI:MGI:3650209|Ensembl:ENSMUSG00000097886|Vega:OTTMUSG00000042561 +544800 Gm12346 MGI:MGI:3649810 +544806 Tmem92 MGI:MGI:3034723|Ensembl:ENSMUSG00000075610|Vega:OTTMUSG00000002047 +544807 Gm11546 MGI:MGI:3705839 +544808 AA623943 MGI:MGI:3035046 +544809 Gm9796 MGI:MGI:3648412 +544810 Gm11536 MGI:MGI:3650116 +544817 Arhgap27 MGI:MGI:1916903|Ensembl:ENSMUSG00000034255|Vega:OTTMUSG00000036599 +544848 Gm5784 MGI:MGI:3647969 +544864 Gm5785 MGI:MGI:3643232 +544872 Gm5786 MGI:MGI:3645003 +544878 Gm5787 MGI:MGI:3811197 +544881 BB287469 MGI:MGI:3034635|Ensembl:ENSMUSG00000079031|Vega:OTTMUSG00000042987 +544883 Gm5788 MGI:MGI:3647569 +544884 Gm5789 MGI:MGI:3779516 +544890 Gm10427 MGI:MGI:3642375 +544896 Ighv5-9 MGI:MGI:4439873|IMGT/GENE-DB:IGHV5-9 +544905 LOC544905 - +544908 LOC544908 - +544917 Gm17177 MGI:MGI:4938004 +544922 Zkscan4 MGI:MGI:3649412|Ensembl:ENSMUSG00000054931|Vega:OTTMUSG00000000421 +544923 Gm11397 MGI:MGI:3709608|Ensembl:ENSMUSG00000071452|Vega:OTTMUSG00000000724 +544927 LOC544927 - +544928 Gm5790 MGI:MGI:3779518 +544940 Gm5791 MGI:MGI:3648515 +544944 Cbx3-ps5 MGI:MGI:3647433 +544945 Gm10770 MGI:MGI:3642046 +544954 Hnrnpa1l2-ps MGI:MGI:3644479 +544960 Gm29680 MGI:MGI:5588839 +544963 Iqgap2 MGI:MGI:2449975|Ensembl:ENSMUSG00000021676 +544971 Bdp1 MGI:MGI:1347077|Ensembl:ENSMUSG00000049658|Vega:OTTMUSG00000035163 +544973 Gm10257 MGI:MGI:3644245 +544974 Gm5793 MGI:MGI:3644190 +544990 Gm5795 MGI:MGI:3779520|Ensembl:ENSMUSG00000079409|Vega:OTTMUSG00000036281 +544998 Gm16440 MGI:MGI:3647179 +545005 LOC545005 - +545007 Gm5796 MGI:MGI:3779522|Ensembl:ENSMUSG00000096775|Vega:OTTMUSG00000036035 +545013 Gm5797 MGI:MGI:3646487|Ensembl:ENSMUSG00000072726|Vega:OTTMUSG00000035716 +545030 Wdfy4 MGI:MGI:3584510|Ensembl:ENSMUSG00000051506|Vega:OTTMUSG00000027929 +545032 LOC545032 - +545034 Gm5798 MGI:MGI:3779524 +545039 Gm5799 MGI:MGI:3646715 +545047 Gm5800 MGI:MGI:3648769|Ensembl:ENSMUSG00000068506|Vega:OTTMUSG00000036423 +545055 Cma2 MGI:MGI:88426|Ensembl:ENSMUSG00000068289 +545056 Gm5801 MGI:MGI:3646055 +545062 Gm5802 MGI:MGI:3643080 +545085 Wdr70 MGI:MGI:1921020|Ensembl:ENSMUSG00000039828 +545086 LOC545086 - +545091 Hnrnpa1l2-ps2 MGI:MGI:3645633 +545115 Apol10c-ps MGI:MGI:3646982 +545121 Gm5805 MGI:MGI:3644633 +545123 Cyp2d11 MGI:MGI:88603|Ensembl:ENSMUSG00000068085 +545124 Tdg-ps MGI:MGI:3645587 +545126 CN725425 MGI:MGI:3613655 +545136 Fam186b MGI:MGI:3647604|Ensembl:ENSMUSG00000078907 +545137 Gm5808 MGI:MGI:3648628 +545140 Olfr288 MGI:MGI:3030122|Ensembl:ENSMUSG00000075427 +545152 Gm5809 MGI:MGI:3647324 +545156 Kalrn MGI:MGI:2685385|Ensembl:ENSMUSG00000061751|Vega:OTTMUSG00000017795 +545172 Rpl21-ps5 MGI:MGI:3647087 +545178 Gm15310 MGI:MGI:3708111 +545180 Gm21859 MGI:MGI:5434023|Ensembl:ENSMUSG00000095369 +545182 Gm9861 MGI:MGI:3642238 +545184 Gm5812 MGI:MGI:3644887 +545192 Baiap3 MGI:MGI:2685783|Ensembl:ENSMUSG00000047507|Vega:OTTMUSG00000036443 +545198 LOC545198 - +545204 Stk-ps1 MGI:MGI:2685164 +545205 Olfr111 MGI:MGI:2177494|Ensembl:ENSMUSG00000090675|Vega:OTTMUSG00000037460 +545207 E130008D07Rik MGI:MGI:3584523 +545208 Gm5814 MGI:MGI:3648910 +545216 Gm5815 MGI:MGI:3648184 +545226 Rpl21-ps7 MGI:MGI:3646135 +545228 Gm5817 MGI:MGI:3779527 +545234 Rpsa-ps8 MGI:MGI:3646814 +545238 G430049J08Rik MGI:MGI:3645649 +545242 Gm5819 MGI:MGI:3643122 +545253 Gm5820 MGI:MGI:3646292|Ensembl:ENSMUSG00000036452 +545257 Gm5821 MGI:MGI:3646289 +545260 Arsi MGI:MGI:2670959|Ensembl:ENSMUSG00000036412|Vega:OTTMUSG00000028985 +545261 Bvht MGI:MGI:5434104|Ensembl:ENSMUSG00000098098 +545262 Gm5822 MGI:MGI:3648836 +545267 Gm5823 MGI:MGI:3647390 +545269 Gm5824 MGI:MGI:3649139 +545271 Gm5826 MGI:MGI:3646075 +545276 Gal3st3 MGI:MGI:3617843|Ensembl:ENSMUSG00000047658 +545279 Ms4a15 MGI:MGI:3617853|Ensembl:ENSMUSG00000067571|Vega:OTTMUSG00000028408 +545280 A630010A05Rik MGI:MGI:3584518|Ensembl:ENSMUSG00000075395|Vega:OTTMUSG00000028596 +545285 LOC545285 - +545288 Cyp2c67 MGI:MGI:3612288|Ensembl:ENSMUSG00000062624|Vega:OTTMUSG00000028411 +545289 Gm5827 MGI:MGI:3647389 +545291 Hpse2 MGI:MGI:2685814|Ensembl:ENSMUSG00000074852 +545302 Gm9826 MGI:MGI:3642725 +545306 Gm5828 MGI:MGI:3644176 +545326 Gm5829 MGI:MGI:3644438 +545332 Gm5830 MGI:MGI:3647375 +545339 Gm5831 MGI:MGI:3779529 +545344 Gm5832 MGI:MGI:3643737 +545363 Gm5833 MGI:MGI:3779530|Ensembl:ENSMUSG00000100459 +545366 Cfhr2 MGI:MGI:3611575|Ensembl:ENSMUSG00000033898|Vega:OTTMUSG00000033649 +545367 Gm5834 MGI:MGI:3643955 +545369 Gm5835 MGI:MGI:3643957 +545370 Hmcn1 MGI:MGI:2685047|Ensembl:ENSMUSG00000066842|Vega:OTTMUSG00000021664 +545378 Sh2d1b2 MGI:MGI:3622649|Ensembl:ENSMUSG00000073494|Vega:OTTMUSG00000019331 +545384 Ifi214 MGI:MGI:3584522|Ensembl:ENSMUSG00000070501|Vega:OTTMUSG00000033419 +545388 Rbm8a2 MGI:MGI:3612447 +545389 Cep170 MGI:MGI:1918348|Ensembl:ENSMUSG00000057335|Vega:OTTMUSG00000050317 +545391 Gm16432 MGI:MGI:3645414|Ensembl:ENSMUSG00000091476|Vega:OTTMUSG00000050375 +545396 Gm5836 MGI:MGI:3648384 +545399 Gm5837 MGI:MGI:3648028 +545403 LOC545403 - +545410 Fcnaos MGI:MGI:3701343 +545417 Olfr367-ps MGI:MGI:3030201 +545423 Gm13653 MGI:MGI:3649358 +545428 Ccdc141 MGI:MGI:1919735|Ensembl:ENSMUSG00000044033|Vega:OTTMUSG00000013215 +545429 Gm13680 MGI:MGI:3652285 +545432 Gm13695 MGI:MGI:3702066 +545443 Olfr1177-ps MGI:MGI:3031011 +545447 Olfr1285 MGI:MGI:3031119 +545459 Gm10766 MGI:MGI:3642134 +545461 Gm14026 MGI:MGI:3649712 +545463 Gm14046 MGI:MGI:3650215 +545466 LOC545466 - +545470 Gm5839 MGI:MGI:3647737 +545471 Zfp345 MGI:MGI:3652219|Ensembl:ENSMUSG00000074731|Vega:OTTMUSG00000015743 +545472 Gm14121 MGI:MGI:3651769 +545474 Scrt2 MGI:MGI:2139287|Ensembl:ENSMUSG00000060257|Vega:OTTMUSG00000015826 +545475 Defb28 MGI:MGI:3650536|Ensembl:ENSMUSG00000074679|Vega:OTTMUSG00000015852 +545477 Bpifa6 MGI:MGI:3647736|Ensembl:ENSMUSG00000078998|Vega:OTTMUSG00000016856 +545481 Arhgap40 MGI:MGI:3649852|Ensembl:ENSMUSG00000074625|Vega:OTTMUSG00000015933 +545486 Tubb1 MGI:MGI:107814|Ensembl:ENSMUSG00000016255|Vega:OTTMUSG00000016460 +545487 Gm14439 MGI:MGI:3652090 +545490 Zfp973 MGI:MGI:3615331|Ensembl:ENSMUSG00000078879|Vega:OTTMUSG00000016252 +545500 Gm5841 MGI:MGI:3645248 +545506 Gm5842 MGI:MGI:3645251 +545507 Gm5843 MGI:MGI:3645250 +545508 Gm5844 MGI:MGI:3645252 +545510 Gm10258 MGI:MGI:3648282 +545512 Gm5845 MGI:MGI:3649050 +545517 Gm10356 MGI:MGI:3641761 +545519 Gm5846 MGI:MGI:3643624 +545524 Gm10254 MGI:MGI:3708673 +545527 Erich6 MGI:MGI:3588212|Ensembl:ENSMUSG00000070471|Vega:OTTMUSG00000052674 +545530 Gm5847 MGI:MGI:3648046 +545531 Gm5848 MGI:MGI:3648047 +545536 Gm10704 MGI:MGI:3642446 +545539 Gm15417 MGI:MGI:3642531|Ensembl:ENSMUSG00000074466 +545541 Gm5849 MGI:MGI:3645655 +545543 Gm5850 MGI:MGI:3645657 +545545 Gm5851 MGI:MGI:3645652 +545546 2210017I01Rik MGI:MGI:3588251 +545547 Lce1j MGI:MGI:3702532|Ensembl:ENSMUSG00000068887|Vega:OTTMUSG00000045066 +545548 Lce3a MGI:MGI:3645650|Ensembl:ENSMUSG00000054325|Vega:OTTMUSG00000051903 +545550 Gm5852 MGI:MGI:3643132 +545551 BC021767 MGI:MGI:3615512 +545554 Ankrd34a MGI:MGI:3617846|Ensembl:ENSMUSG00000049097|Vega:OTTMUSG00000035254 +545555 Gm5853 MGI:MGI:3648707 +545556 Gm12428 MGI:MGI:3650848 +545557 Gm12474 MGI:MGI:3649378 +545562 Amy2b MGI:MGI:104547 +545567 Gm5854 MGI:MGI:3645469 +545568 Gm5855 MGI:MGI:3645472 +545572 Gm5857 MGI:MGI:3644956 +545578 Gm5858 MGI:MGI:3648487 +545589 Gm12919 MGI:MGI:3652001 +545592 Gm11847 MGI:MGI:3651787 +545600 Gm12372 MGI:MGI:3650289 +545605 Gm5859 MGI:MGI:3704096 +545611 Fam205a2 MGI:MGI:3701946|Ensembl:ENSMUSG00000094066|Vega:OTTMUSG00000034239 +545614 Gm10590 MGI:MGI:3641654 +545618 Gm12463 MGI:MGI:3650648 +545622 Ptpn3 MGI:MGI:105307|Ensembl:ENSMUSG00000038764|Vega:OTTMUSG00000007367 +545637 Gm11758 MGI:MGI:3702099|Ensembl:ENSMUSG00000096530|Vega:OTTMUSG00000004013 +545640 Gm14138 MGI:MGI:3649496 +545641 Gm5860 MGI:MGI:3646172|Ensembl:ENSMUSG00000085022 +545645 Gm13283 MGI:MGI:3649573|Ensembl:ENSMUSG00000100505|Vega:OTTMUSG00000011280 +545646 Gm13290 MGI:MGI:3701990|Ensembl:ENSMUSG00000094271|Vega:OTTMUSG00000011291 +545647 Gm13289 MGI:MGI:3701987|Ensembl:ENSMUSG00000096582|Vega:OTTMUSG00000011290 +545648 Gm13272 MGI:MGI:3701968|Ensembl:ENSMUSG00000096591|Vega:OTTMUSG00000011265 +545649 Gm13276 MGI:MGI:3701972|Ensembl:ENSMUSG00000099545|Vega:OTTMUSG00000011269 +545650 Gm13277 MGI:MGI:3701974|Ensembl:ENSMUSG00000100234|Vega:OTTMUSG00000011270 +545651 Gm13278 MGI:MGI:3701976|Ensembl:ENSMUSG00000101163|Vega:OTTMUSG00000011272 +545652 Gm13275 MGI:MGI:3701970|Ensembl:ENSMUSG00000099518|Vega:OTTMUSG00000011268 +545653 Gm13279 MGI:MGI:3701978|Ensembl:ENSMUSG00000099420|Vega:OTTMUSG00000011273 +545654 Gm13285 MGI:MGI:3701981|Ensembl:ENSMUSG00000095101|Vega:OTTMUSG00000011282 +545655 Gm13287 MGI:MGI:3701983|Ensembl:ENSMUSG00000094648|Vega:OTTMUSG00000011285 +545660 I0C0044D17Rik MGI:MGI:3588230|Ensembl:ENSMUSG00000073794|Vega:OTTMUSG00000025486 +545662 B020004J07Rik MGI:MGI:3588238|Ensembl:ENSMUSG00000035201|Vega:OTTMUSG00000008455 +545667 Fam159a MGI:MGI:3651644|Ensembl:ENSMUSG00000059816|Vega:OTTMUSG00000008243 +545668 Gm12818 MGI:MGI:3649634 +545675 Gm12859 MGI:MGI:3651649 +545677 Gm12888 MGI:MGI:3652130|Ensembl:ENSMUSG00000073764|Vega:OTTMUSG00000008911 +545681 Gm12992 MGI:MGI:3702644|Ensembl:ENSMUSG00000085667 +545683 Gm13213 MGI:MGI:3651606 +545691 Fhad1os1 MGI:MGI:3649995|Ensembl:ENSMUSG00000085424 +545693 Gm13043 MGI:MGI:3649500|Ensembl:ENSMUSG00000095409|Vega:OTTMUSG00000010136 +545700 Smarca5-ps MGI:MGI:2443330|Ensembl:ENSMUSG00000052912 +545701 Gm13226 MGI:MGI:3651282 +545703 Gm13231 MGI:MGI:3649243 +545704 Gm13244 MGI:MGI:3650036 +545716 Gm13135 MGI:MGI:3650404 +545718 Gm13141 MGI:MGI:3651744 +545725 Mterf1a MGI:MGI:1918240|Ensembl:ENSMUSG00000040429|Vega:OTTMUSG00000028565 +545728 Gm5861 MGI:MGI:3644254|Ensembl:ENSMUSG00000095918|Vega:OTTMUSG00000036521 +545732 4933402N22Rik MGI:MGI:3703021|Ensembl:ENSMUSG00000067848|Vega:OTTMUSG00000036530 +545739 Gm5862 MGI:MGI:3645135|Ensembl:ENSMUSG00000067700|Vega:OTTMUSG00000036609 +545741 Gm5863 MGI:MGI:3648580 +545743 Gm5864 MGI:MGI:3648579 +545747 Gm5865 MGI:MGI:3645504 +545750 Gm5866 MGI:MGI:3645339 +545756 Gm5867 MGI:MGI:3644922 +545758 Gm5868 MGI:MGI:3645333|Ensembl:ENSMUSG00000060204|Vega:OTTMUSG00000026979 +545762 Gm16367 MGI:MGI:3845011|Ensembl:ENSMUSG00000096550 +545763 LOC545763 Ensembl:ENSMUSG00000095475 +545767 Gm5869 MGI:MGI:3648808 +545785 Gm45913 MGI:MGI:5825550 +545790 Gm5870 MGI:MGI:3644057 +545792 Gm5871 MGI:MGI:3644058 +545793 AB010352 MGI:MGI:3642128 +545798 Tmem233 MGI:MGI:3651514|Ensembl:ENSMUSG00000079278|Vega:OTTMUSG00000014722 +545808 Rps2-ps5 MGI:MGI:3647821 +545809 Gm29681 MGI:MGI:5588840|Ensembl:ENSMUSG00000105387 +545812 Pilrb2 MGI:MGI:2450535|Ensembl:ENSMUSG00000066682|Vega:OTTMUSG00000054650 +545814 Smok3a MGI:MGI:3693943|Ensembl:ENSMUSG00000075599|Vega:OTTMUSG00000030877 +545817 Cyp2w1 MGI:MGI:3616076|Ensembl:ENSMUSG00000029541 +545824 Zar1l MGI:MGI:3690051|Ensembl:ENSMUSG00000056586|Vega:OTTMUSG00000027937 +545826 Gm5873 MGI:MGI:3648385 +545829 Gm5874 MGI:MGI:3648027 +545843 Gm5876 MGI:MGI:3647377 +545847 Igkv14-111 MGI:MGI:4439863|IMGT/GENE-DB:IGKV14-111 +545848 Igkv4-80 MGI:MGI:4439653|IMGT/GENE-DB:IGKV4-80 +545849 Igkv4-78 MGI:MGI:3819775|IMGT/GENE-DB:IGKV4-78 +545850 Igkv5-45 MGI:MGI:4439774|IMGT/GENE-DB:IGKV5-45 +545851 Igkv12-44 MGI:MGI:4439775|IMGT/GENE-DB:IGKV12-44 +545852 Amd-ps2 MGI:MGI:3644437 +545861 Gm5878 MGI:MGI:3647625|Ensembl:ENSMUSG00000072952 +545864 Gm5879 MGI:MGI:3647624 +545866 Gm5880 MGI:MGI:3647623 +545867 Gm5881 MGI:MGI:3779532 +545873 Gm5883 MGI:MGI:3644644 +545874 Vmn2r25 MGI:MGI:3644645|Ensembl:ENSMUSG00000094672|Vega:OTTMUSG00000034579 +545878 Gm5884 MGI:MGI:3644646 +545884 Gm5885 MGI:MGI:3648672 +545886 Gm5886 MGI:MGI:3648674|Ensembl:ENSMUSG00000108106 +545887 Tubb3-ps1 MGI:MGI:3723459 +545893 Mansc4 MGI:MGI:3645619|Ensembl:ENSMUSG00000072662|Vega:OTTMUSG00000026030 +545901 Atp6v0c-ps1 MGI:MGI:2151814 +545902 Ptprh MGI:MGI:3026877|Ensembl:ENSMUSG00000035429|Vega:OTTMUSG00000058448 +545909 Vmn2r39 MGI:MGI:3704108|Ensembl:ENSMUSG00000096658|Vega:OTTMUSG00000037996 +545911 Gm5888 MGI:MGI:3645955 +545912 Zscan4-ps1 MGI:MGI:3645953 +545913 Zscan4d MGI:MGI:3645954|Ensembl:ENSMUSG00000090714|Vega:OTTMUSG00000042375 +545921 Obox3-ps6 MGI:MGI:3704111 +545925 Psg27 MGI:MGI:1891359|Ensembl:ENSMUSG00000070797|Vega:OTTMUSG00000058902 +545926 Gm5890 MGI:MGI:3649012 +545929 Gm5891 MGI:MGI:3649014|Ensembl:ENSMUSG00000095976|Vega:OTTMUSG00000045834 +545934 Vmn1r173 MGI:MGI:3645760|Ensembl:ENSMUSG00000074289|Vega:OTTMUSG00000038006 +545936 Gm5893 MGI:MGI:3645761|Ensembl:ENSMUSG00000011350 +545938 Zfp607a MGI:MGI:3584526|Ensembl:ENSMUSG00000020420|Vega:OTTMUSG00000058619 +545947 Scgb2b19 MGI:MGI:3648809|Ensembl:ENSMUSG00000096467|Vega:OTTMUSG00000045816 +545948 Scgb1b20 MGI:MGI:3648810|Ensembl:ENSMUSG00000094978|Vega:OTTMUSG00000045851 +545951 Gm28453 MGI:MGI:5579159|Ensembl:ENSMUSG00000101708 +545955 Gm5896 MGI:MGI:3645545 +545963 Gm5897 MGI:MGI:3648578 +545964 LOC545964 - +545966 LOC545966 - +545971 Gm5898 MGI:MGI:3644921 +545975 Cers3 MGI:MGI:2681008|Ensembl:ENSMUSG00000030510|Vega:OTTMUSG00000042001 +545982 Gm5899 MGI:MGI:3643908 +545985 Olfr612 MGI:MGI:3030446|Ensembl:ENSMUSG00000094119|Vega:OTTMUSG00000019075 +545987 Gm5900 MGI:MGI:3643907 +546005 Gm5903 MGI:MGI:3644470 +546009 Gm5904 MGI:MGI:3644469 +546015 Gm5905 MGI:MGI:3647422 +546024 Crxos MGI:MGI:2451355|Ensembl:ENSMUSG00000074365|Vega:OTTMUSG00000029355 +546036 Gm5907 MGI:MGI:3643437|Ensembl:ENSMUSG00000110058 +546038 Spag11b MGI:MGI:3647173|Ensembl:ENSMUSG00000059463|Vega:OTTMUSG00000020593 +546049 C330021F23Rik MGI:MGI:3612471|Ensembl:ENSMUSG00000065952|Vega:OTTMUSG00000033953 +546052 Gm5908 MGI:MGI:3646940 +546055 Adam39 MGI:MGI:3045694|Ensembl:ENSMUSG00000054033|Vega:OTTMUSG00000061123 +546058 AA386476 MGI:MGI:3034595 +546061 LOC546061 - +546065 Sp100-rs - +546071 Mast3 MGI:MGI:2683541|Ensembl:ENSMUSG00000031833|Vega:OTTMUSG00000061547 +546075 Gm5909 MGI:MGI:3646686 +546077 Gm5910 MGI:MGI:3646687 +546080 Gm5911 MGI:MGI:3645263 +546088 Gm5912 MGI:MGI:3645264 +546090 Gm5913 MGI:MGI:3648292 +546096 Gm29682 MGI:MGI:5588841|Ensembl:ENSMUSG00000110053 +546100 Gm5914 MGI:MGI:3779534|Ensembl:ENSMUSG00000098120 +546101 Gm5915 MGI:MGI:3642938 +546118 Ubtfl1 MGI:MGI:3588290|Ensembl:ENSMUSG00000074502|Vega:OTTMUSG00000036484 +546123 Gm5916 MGI:MGI:3643162|Ensembl:ENSMUSG00000091411|Vega:OTTMUSG00000044689 +546133 Gm5917 MGI:MGI:3646334 +546134 Gramd2 MGI:MGI:3528937|Ensembl:ENSMUSG00000074259|Vega:OTTMUSG00000033359 +546143 Ccpg1os MGI:MGI:3648770|Ensembl:ENSMUSG00000086158|Vega:OTTMUSG00000033539 +546144 Wdr72 MGI:MGI:3583957|Ensembl:ENSMUSG00000044976|Vega:OTTMUSG00000023578 +546150 Gm5919 MGI:MGI:3645715 +546155 Gm5920 MGI:MGI:3645716 +546157 7420426K07Rik MGI:MGI:3588253|Ensembl:ENSMUSG00000074123|Vega:OTTMUSG00000048287 +546160 Fbxw25 MGI:MGI:3588266 +546161 Fbxw18 MGI:MGI:3505704|Ensembl:ENSMUSG00000074059|Vega:OTTMUSG00000047366 +546164 Gm5921 MGI:MGI:3648968 +546165 Gm10608 MGI:MGI:3642009 +546166 Gm5922 MGI:MGI:3647932 +546176 Gm5923 MGI:MGI:3645924 +546182 Gm5924 MGI:MGI:3779535 +546185 Gm5925 MGI:MGI:3643868 +546205 Gm5926 MGI:MGI:3647272|Ensembl:ENSMUSG00000094601 +546213 Igkv4-53 MGI:MGI:2686266|IMGT/GENE-DB:IGKV4-53 +546216 Mszf17 - +546244 Igkv4-61 MGI:MGI:4439819|IMGT/GENE-DB:IGKV4-61 +546246 Gm5928 MGI:MGI:3646762 +546249 Gm5929 MGI:MGI:3646763 +546250 Gm5930 MGI:MGI:3643645 +546263 Gm14459 MGI:MGI:3650385|Ensembl:ENSMUSG00000079704|Vega:OTTMUSG00000016698 +546265 Gm5931 MGI:MGI:3647036 +546268 Gm5932 MGI:MGI:3647035 +546272 Gm5934 MGI:MGI:3643862|Ensembl:ENSMUSG00000084063|Vega:OTTMUSG00000016996 +546282 Gm5935 MGI:MGI:3646322|Ensembl:ENSMUSG00000093923|Vega:OTTMUSG00000016995 +546294 Rhox3g MGI:MGI:3770313|Ensembl:ENSMUSG00000080933|Vega:OTTMUSG00000017157 +546295 Rhox3d-ps MGI:MGI:3770270 +546298 Rps2-ps13 MGI:MGI:3705640 +546321 Gm15365 MGI:MGI:3705398 +546325 Gm5936 MGI:MGI:3645575|Ensembl:ENSMUSG00000079531|Vega:OTTMUSG00000017902 +546331 Gm5937 MGI:MGI:3648844 +546335 Gm5938 MGI:MGI:3648846|Ensembl:ENSMUSG00000079521|Vega:OTTMUSG00000017865 +546336 Prrg1 MGI:MGI:1917364|Ensembl:ENSMUSG00000047996|Vega:OTTMUSG00000017869 +546337 Gm5939 MGI:MGI:3648845 +546338 Gm5940 MGI:MGI:3648847 +546347 Gm5941 MGI:MGI:3646197|Ensembl:ENSMUSG00000071726|Vega:OTTMUSG00000017965 +546361 Gm5942 MGI:MGI:3646003 +546362 Gm5943 MGI:MGI:3646004 +546363 Gm5944 MGI:MGI:3646005 +546368 Gm5945 MGI:MGI:3646000 +546387 Gm5946 MGI:MGI:3644989 +546397 Gm5947 MGI:MGI:3648189 +546401 Gm15204 MGI:MGI:3648402 +546472 Gm5948 MGI:MGI:3645376 +546475 Gm5949 MGI:MGI:3645374 +546476 Gm5950 MGI:MGI:3645375 +546482 Gm5951 MGI:MGI:3647256 +546486 Fam119b MGI:MGI:3645330 +546487 Olfr766-ps1 MGI:MGI:3030600 +546488 Olfr785 MGI:MGI:3030619|Ensembl:ENSMUSG00000111732|Vega:OTTMUSG00000056566 +546497 Gm12181 MGI:MGI:3651492 +546500 Rpl9-ps3 MGI:MGI:3650675 +546511 Gm11555 MGI:MGI:3651823|Ensembl:ENSMUSG00000078130|Vega:OTTMUSG00000002181 +546519 Tmem235 MGI:MGI:3651706|Ensembl:ENSMUSG00000070330|Vega:OTTMUSG00000007589 +546524 Gm5953 MGI:MGI:3647171 +546534 Gm5954 MGI:MGI:3644230 +546543 Gm5955 MGI:MGI:3779537 +546546 Serpina3h MGI:MGI:2182839 +546611 Klhl33 MGI:MGI:3644593|Ensembl:ENSMUSG00000090799 +546612 Trav4d-2 MGI:MGI:3650629|IMGT/GENE-DB:TRAV4D-2 +546623 Gm5958 MGI:MGI:3647972 +546638 Ube2d4 MGI:MGI:3644823 +546642 Gm5960 MGI:MGI:3779540 +546643 I830127L07Rik MGI:MGI:3612406 +546644 Ly6g MGI:MGI:109440|Ensembl:ENSMUSG00000022582|Vega:OTTMUSG00000045113 +546648 Klhdc7b MGI:MGI:3648212|Ensembl:ENSMUSG00000091680|Vega:OTTMUSG00000044890 +546651 Rpl10a-ps3 MGI:MGI:3645006 +546659 Gm5962 MGI:MGI:3645008 +546663 Gm5963 MGI:MGI:3648418 +546665 Gm5964 MGI:MGI:3648416 +546667 Gm15554 MGI:MGI:3783003 +546672 Gm5965 MGI:MGI:3645197 +546683 Gm5966 MGI:MGI:3648615 +546691 Gm5967 MGI:MGI:3645388 +546695 Gm16519 MGI:MGI:4360871 +546708 Gm5968 MGI:MGI:3643648 +546710 Gm5969 MGI:MGI:3647555 +546714 Gm5970 MGI:MGI:3646761 +546719 Gm5971 MGI:MGI:3646764 +546723 Ppp1r2-ps3 MGI:MGI:3645534 +546726 Cyp26c1 MGI:MGI:2679699|Ensembl:ENSMUSG00000062432 +546729 Calhm1 MGI:MGI:3643383|Ensembl:ENSMUSG00000079258 +546733 Gm5973 MGI:MGI:3646541 +546734 Gm5974 MGI:MGI:3646540 +546735 Gm5975 MGI:MGI:3646539 +546736 Gm5976 MGI:MGI:3646538 +546747 Olfr220 MGI:MGI:3030054|Ensembl:ENSMUSG00000066671|Vega:OTTMUSG00000050223 +546752 Gm5977 MGI:MGI:3779541 +546767 Gm13735 MGI:MGI:3650011 +546769 Olfr1174-ps MGI:MGI:3031008 +546770 Olfr1175-ps MGI:MGI:3031009 +546780 Gm11462 MGI:MGI:3650020 +546797 Gm5978 MGI:MGI:3645904 +546801 Etv3l MGI:MGI:3646099 +546802 Gm5979 MGI:MGI:3643641 +546810 Gm5981 MGI:MGI:3649175 +546811 Gm5982 MGI:MGI:3649176 +546818 Gm5983 MGI:MGI:3649177 +546828 Gm11829 MGI:MGI:3649804 +546829 Gm11895 MGI:MGI:3651868 +546832 Mup-ps21 MGI:MGI:3652151 +546834 Gm13281 MGI:MGI:3649513 +546835 Gm13282 MGI:MGI:3649258 +546837 Cyp2j7 MGI:MGI:2449816 +546840 Ldlrad1 MGI:MGI:3652166|Ensembl:ENSMUSG00000070877|Vega:OTTMUSG00000008594 +546842 Cyp4a30-ps MGI:MGI:3649426 +546843 Gm12848 MGI:MGI:3650820 +546849 Gm13178 MGI:MGI:3650721|Ensembl:ENSMUSG00000041735|Vega:OTTMUSG00000010750 +546854 Gm5984 MGI:MGI:3648732 +546876 LOC546876 - +546882 Gm5987 MGI:MGI:3644525 +546886 Cfap73 MGI:MGI:3779542|Ensembl:ENSMUSG00000094282|Vega:OTTMUSG00000056253 +546894 Gm5989 MGI:MGI:3643846 +546896 Olfr455 MGI:MGI:3030289|Ensembl:ENSMUSG00000071494|Vega:OTTMUSG00000035933 +546897 Gm5990 MGI:MGI:3648301 +546901 Vmn1r34 MGI:MGI:3644800|Ensembl:ENSMUSG00000091012|Vega:OTTMUSG00000040009 +546902 Vmn1r-ps24 MGI:MGI:3644801 +546903 Vmn1r39 MGI:MGI:3644802|Ensembl:ENSMUSG00000093755|Vega:OTTMUSG00000040015 +546905 Igkv8-31 MGI:MGI:3644798|IMGT/GENE-DB:IGKV8-31 +546907 Gm5995 MGI:MGI:3644799 +546912 Vmn2r21 MGI:MGI:3647953|Ensembl:ENSMUSG00000093820|Vega:OTTMUSG00000040018 +546913 Vmn2r22 MGI:MGI:3647952|Ensembl:ENSMUSG00000095486|Vega:OTTMUSG00000040029 +546917 Gm15707 MGI:MGI:3783147 +546931 Gm5996 MGI:MGI:3643168 +546936 Gm5997 MGI:MGI:3648188 +546943 Vmn1r176 MGI:MGI:3809206|Ensembl:ENSMUSG00000096859|Vega:OTTMUSG00000038010 +546944 Vmn1r170 MGI:MGI:3644326|Ensembl:ENSMUSG00000094187|Vega:OTTMUSG00000038003 +546947 Rpl23a-ps8 MGI:MGI:3644328 +546949 Rpl23a-ps9 MGI:MGI:3644329 +546951 Rpl23a-ps10 MGI:MGI:3645318 +546954 Gm6003 MGI:MGI:3647537 +546957 Gm20749 MGI:MGI:5434105 +546964 Vmn2r62 MGI:MGI:3757994|Ensembl:ENSMUSG00000091926|Vega:OTTMUSG00000037911 +546965 Gm6004 MGI:MGI:3644564 +546979 Gm6006 MGI:MGI:3779543 +546980 Vmn2r74 MGI:MGI:3643877|Ensembl:ENSMUSG00000090774|Vega:OTTMUSG00000037828 +546981 Vmn2r75 MGI:MGI:3648311|Ensembl:ENSMUSG00000090436|Vega:OTTMUSG00000037753 +546983 Vmn2r77 MGI:MGI:3643879|Ensembl:ENSMUSG00000090949|Vega:OTTMUSG00000037778 +546989 Olfr607 MGI:MGI:3030441 +546990 Gm6007 MGI:MGI:3647052 +546993 Gm6008 MGI:MGI:3647051 +546994 Gm16475 MGI:MGI:3644715 +547006 Gm6009 MGI:MGI:3647295 +547011 Gm6011 MGI:MGI:3644337 +547012 Gm6012 MGI:MGI:3644785 +547022 Gm6013 MGI:MGI:3648988 +547023 Gm6014 MGI:MGI:3648989 +547033 Gm6015 MGI:MGI:3644127 +547035 Kdm4dl MGI:MGI:3644125 +547043 Gm6018 MGI:MGI:3646809 +547049 Iqcf2 MGI:MGI:3646813 +547057 Gm6019 MGI:MGI:3643890 +547091 Gm6020 MGI:MGI:3643428 +547097 B020011L13Rik MGI:MGI:3588191 +547103 Gm10674 MGI:MGI:3644111 +547109 Trim43a MGI:MGI:3645218|Ensembl:ENSMUSG00000090693|Vega:OTTMUSG00000045601 +547127 Tmem181b-ps MGI:MGI:3779544 +547150 6820431F20Rik MGI:MGI:3694236|Ensembl:ENSMUSG00000071796 +547154 H2al1k MGI:MGI:3710586|Ensembl:ENSMUSG00000100448|Vega:OTTMUSG00000016887 +547156 Gm14485 MGI:MGI:3649618 +547160 H2al1e MGI:MGI:3649617|Ensembl:ENSMUSG00000095413|Vega:OTTMUSG00000016790 +547166 Gm6023 MGI:MGI:3645815 +547168 Rhox7a MGI:MGI:3580246|Ensembl:ENSMUSG00000071767|Vega:OTTMUSG00000017133 +547170 Gm14564 MGI:MGI:3647345 +547171 Gm6024 MGI:MGI:3648877 +547172 Gm6025 MGI:MGI:3646091 +547176 Zc3h12b MGI:MGI:2442133|Ensembl:ENSMUSG00000035045|Vega:OTTMUSG00000018125 +547182 Gm14855 MGI:MGI:3646035 +547210 H2al2c MGI:MGI:3779546|Ensembl:ENSMUSG00000094881 +547213 LOC547213 - +547215 Gm6027 MGI:MGI:3648335 +547220 Cyp4a28-ps MGI:MGI:1932405 +547247 Gm6028 MGI:MGI:3648170 +547253 Parp14 MGI:MGI:1919489|Ensembl:ENSMUSG00000034422|Vega:OTTMUSG00000027273 +547263 Gm6029 MGI:MGI:3643236 +547267 Gm6030 MGI:MGI:3645112 +547302 Gm6031 MGI:MGI:3645805 +547311 Gm6032 MGI:MGI:3648870 +547323 LOC547323 - +547328 Trav13n-3 MGI:MGI:3645598|IMGT/GENE-DB:TRAV13N-3 +547329 Trav16d-dv11 MGI:MGI:3704436|IMGT/GENE-DB:TRAV16D/DV11 +547330 Trav14-3 MGI:MGI:3702149|IMGT/GENE-DB:TRAV14-3 +547334 Fhitos MGI:MGI:4414962|Ensembl:ENSMUSG00000089833 +547347 Gm6034 MGI:MGI:3646212|Ensembl:ENSMUSG00000073407|Vega:OTTMUSG00000037518 +547348 H2-T3-like - +547349 LOC547349 - +547402 Gm6035 MGI:MGI:3643289 +547412 Fam220-ps MGI:MGI:3707456 +547416 Cycl MGI:MGI:894272 +547420 Trav7-3 MGI:MGI:3649556|IMGT/GENE-DB:TRAV7-3 +547424 Trav15n-2 MGI:MGI:3649172|IMGT/GENE-DB:TRAV15N-2 +547427 Trav18 MGI:MGI:3649382|IMGT/GENE-DB:TRAV18 +547428 Trav19 MGI:MGI:3649383 +547431 Btnl2 MGI:MGI:1859549|Ensembl:ENSMUSG00000024340|Vega:OTTMUSG00000020172 +547447 Gm6038 MGI:MGI:3643766 +548102 LOC548102 - +548103 LOC548103 - +548632 BC023719 MGI:MGI:3574836 +548633 D19Mgc5 MGI:MGI:3574847 +550619 Arid3c MGI:MGI:3650624|Ensembl:ENSMUSG00000066224|Vega:OTTMUSG00000006683 +552873 LOC552873 - +552874 LOC552874 - +552875 AU015680 MGI:MGI:2143191 +552876 LOC552876 - +552877 LOC552877 - +552878 C130023C23Rik MGI:MGI:4437794 +552881 LOC552881 - +552882 LOC552882 - +552890 LOC552890 - +552899 Ugt2a2 MGI:MGI:3576095|Ensembl:ENSMUSG00000029268|Vega:OTTMUSG00000026801 +552901 LOC552901 - +552902 LOC552902 - +552903 LOC552903 - +552904 LOC552904 - +552906 LOC552906 - +552907 LOC552907 - +552908 LOC552908 - +552909 LOC552909 - +552911 LOC552911 - +552913 Gm14634 MGI:MGI:3705147|Ensembl:ENSMUSG00000085891 +553089 LOC553089 - +553090 LOC553090 - +553093 LOC553093 - +553095 Gm17750 MGI:MGI:5009828|Ensembl:ENSMUSG00000098087 +553096 LOC553096 - +553127 Cxx1b MGI:MGI:3576504|Ensembl:ENSMUSG00000067924|Vega:OTTMUSG00000017369 +554158 BB431852 MGI:MGI:3034955 +554159 BB453382 MGI:MGI:3035402 +554160 BB283564 MGI:MGI:3034568 +554161 AA438147 MGI:MGI:3034621 +554162 AA681502 MGI:MGI:3035159 +554292 Methig1 MGI:MGI:3845761|Ensembl:ENSMUSG00000093789|Vega:OTTMUSG00000042221 +554327 2610042L04Rik MGI:MGI:1914305|Ensembl:ENSMUSG00000079388|Vega:OTTMUSG00000036015 +572559 Gm6039 MGI:MGI:3648055 +574081 Defb46 MGI:MGI:3646525|Ensembl:ENSMUSG00000071169|Vega:OTTMUSG00000020619 +574401 AB193402 MGI:MGI:3581225 +574402 Gpr17 MGI:MGI:3584514|Ensembl:ENSMUSG00000052229|Vega:OTTMUSG00000023990 +574403 Fam196b MGI:MGI:3643491|Ensembl:ENSMUSG00000069911 +574404 Gm14685 MGI:MGI:3710618|Ensembl:ENSMUSG00000067771|Vega:OTTMUSG00000017677 +574405 DXBay18 MGI:MGI:99870|Ensembl:ENSMUSG00000071745|Vega:OTTMUSG00000017685 +574415 Gm6042 MGI:MGI:3646630 +574416 Gm11597 MGI:MGI:3652313 +574417 Tas2r137 MGI:MGI:3606604|Ensembl:ENSMUSG00000052850|Vega:OTTMUSG00000056376 +574418 Serinc4 Ensembl:ENSMUSG00000046110|Vega:OTTMUSG00000015331 +574428 Zmynd15 MGI:MGI:3603821|Ensembl:ENSMUSG00000040829|Vega:OTTMUSG00000006043 +574429 Psg26 MGI:MGI:1891358|Ensembl:ENSMUSG00000070799|Vega:OTTMUSG00000058900 +574437 Xlr3b MGI:MGI:109505|Ensembl:ENSMUSG00000073125|Vega:OTTMUSG00000017657 +574438 Xlr5a MGI:MGI:3574108|Ensembl:ENSMUSG00000058328|Vega:OTTMUSG00000017649 +574519 Vax2os MGI:MGI:3583301|Ensembl:ENSMUSG00000085794 +574528 Gm11507 MGI:MGI:3650927 +594843 Has2os MGI:MGI:3643465|Ensembl:ENSMUSG00000086541 +594844 Tceal3 MGI:MGI:1913354|Ensembl:ENSMUSG00000044550|Vega:OTTMUSG00000018706 +595136 Ndufs5 MGI:MGI:1890889|Ensembl:ENSMUSG00000028648|Vega:OTTMUSG00000009217 +595138 Gm6043 MGI:MGI:3805955 +595139 E030024N20Rik MGI:MGI:2442009 +595140 Gm6044 MGI:MGI:3648725 +595141 Gm6045 MGI:MGI:3648726 +595150 Gm6046 MGI:MGI:3645682 +606492 Gm15621 MGI:MGI:3783066 +606496 Gsk3a MGI:MGI:2152453|Ensembl:ENSMUSG00000057177|Vega:OTTMUSG00000021123 +606497 Otx2os1 MGI:MGI:3583292|Ensembl:ENSMUSG00000098682 +606510 Gm6047 MGI:MGI:3779547 +606511 Gm6048 MGI:MGI:3645583 +606512 Gm6049 MGI:MGI:3645582 +606514 Gm6050 MGI:MGI:3779548 +606515 Gabarapl2-ps MGI:MGI:4358479 +606516 Gm6051 MGI:MGI:3645584 +606517 Gm6052 MGI:MGI:3645585 +606518 Gm6053 MGI:MGI:3645580 +606519 Gm6054 MGI:MGI:3645581 +606520 Gm6055 MGI:MGI:3648620 +606521 Gm6056 MGI:MGI:3648619 +606522 Gm6057 MGI:MGI:3648618 +606525 Gm6058 MGI:MGI:3648617 +606527 Gm6059 MGI:MGI:3779549 +606528 Gm6060 MGI:MGI:3648622 +606529 Gm6061 MGI:MGI:3648621 +606530 Gm13493 MGI:MGI:3650824 +606531 Gm6062 MGI:MGI:3645240 +606532 Gm6063 MGI:MGI:3645395 +606533 Gm6064 MGI:MGI:3645396 +606534 Gm6065 MGI:MGI:3645391 +606535 Gm6066 MGI:MGI:3645392 +606536 Gm12632 MGI:MGI:3650967 +606537 Gm6067 MGI:MGI:3645393 +606538 Gm13679 MGI:MGI:3652284 +606539 Gm6702 MGI:MGI:3643910 +606540 Gm12842 MGI:MGI:3651050 +606541 Gm6068 MGI:MGI:3648419 +606542 Gm6069 MGI:MGI:3648422 +606543 Gm6070 MGI:MGI:3648421 +606544 Gm6071 MGI:MGI:3644647 +606545 Gm6072 MGI:MGI:3648423 +606546 Gm13400 MGI:MGI:3649558 +606547 Gm6073 MGI:MGI:3648425 +606714 Gm12071 MGI:MGI:3650750 +606715 Gm6074 MGI:MGI:3648506 +606716 Gm6075 MGI:MGI:3648507 +606717 Gm6076 MGI:MGI:3648508 +606718 Gm6077 MGI:MGI:3648504 +606725 Gm6078 MGI:MGI:3645679 +606726 Gm6079 MGI:MGI:3645681 +606727 Gm14534 MGI:MGI:3705635 +606728 Gm6080 MGI:MGI:3645684 +606729 Gm6081 MGI:MGI:3645683 +606730 Gm6082 MGI:MGI:3648724 +606731 Gm11700 MGI:MGI:3650078 +606732 Gm13458 MGI:MGI:3651863 +606733 Gm13454 MGI:MGI:3651619 +606735 A330069E16Rik MGI:MGI:3583899|Ensembl:ENSMUSG00000097868 +606736 C920009B18Rik MGI:MGI:3583961|Ensembl:ENSMUSG00000097352 +613117 4930571B16Rik MGI:MGI:2447814 +613118 Ugt1a3-ps MGI:MGI:3576059 +613119 Ugt1a11-ps MGI:MGI:3576094 +613120 Ugt1a7b-ps MGI:MGI:3580636 +613122 Ugt1a4-ps MGI:MGI:3576061 +613123 Ugt1a8 MGI:MGI:3576090 +613124 Ugt1a7a-ps MGI:MGI:3580634 +613254 AA465934 MGI:MGI:2671018|Ensembl:ENSMUSG00000093483 +613255 AV226208 MGI:MGI:3029440 +613258 A730017L22Rik MGI:MGI:3584452 +613262 BC029722 MGI:MGI:3584273|Ensembl:ENSMUSG00000074649|Vega:OTTMUSG00000016130 +613264 1810020O05Rik MGI:MGI:3586838|Ensembl:ENSMUSG00000089997 +619209 Rr18 MGI:MGI:5431424 +619210 Rmcf2 MGI:MGI:3587808 +619287 Zcchc16 MGI:MGI:3588192|Ensembl:ENSMUSG00000071679|Vega:OTTMUSG00000018930 +619288 Fam71a MGI:MGI:3588202|Ensembl:ENSMUSG00000091017|Vega:OTTMUSG00000051435 +619289 Rfx8 MGI:MGI:3588206|Ensembl:ENSMUSG00000057173|Vega:OTTMUSG00000033905 +619290 A230072I06Rik MGI:MGI:3588221 +619291 5330413D20Rik MGI:MGI:3588224 +619292 G430095P16Rik MGI:MGI:3588227 +619293 9230009I02Rik MGI:MGI:3588229|Ensembl:ENSMUSG00000072982 +619294 Cldn34b4 MGI:MGI:3588232|Ensembl:ENSMUSG00000073085|Vega:OTTMUSG00000017786 +619295 Lrp8os2 MGI:MGI:3588233 +619297 C430049E01Rik MGI:MGI:3588239|Ensembl:ENSMUSG00000108900|Vega:OTTMUSG00000060102 +619298 G930045G22Rik MGI:MGI:3588242 +619299 9230020A06Rik MGI:MGI:3588244 +619300 6430553K19Rik MGI:MGI:3588245 +619301 Tmem253 MGI:MGI:3588246|Ensembl:ENSMUSG00000072571 +619302 1700101G07Rik MGI:MGI:3588248 +619303 4930567H17Rik MGI:MGI:3588249|Ensembl:ENSMUSG00000073141 +619304 I830134H01Rik MGI:MGI:3588250 +619305 4930588K23Rik MGI:MGI:3588254 +619306 B430319F04Rik MGI:MGI:3588258 +619307 9430078G10Rik MGI:MGI:3588259 +619308 F830208F22Rik MGI:MGI:3588261 +619309 Muc3a MGI:MGI:3588263 +619310 Zfp872 MGI:MGI:3588272|Ensembl:ENSMUSG00000074472|Vega:OTTMUSG00000042414 +619311 A730065G17Rik MGI:MGI:3588275 +619312 G730013B05Rik MGI:MGI:3588276 +619313 I730030J21Rik MGI:MGI:3588279 +619314 B020014A21Rik MGI:MGI:3588281|Ensembl:ENSMUSG00000110909 +619318 4930432M17Rik MGI:MGI:3588188|Ensembl:ENSMUSG00000074248|Vega:OTTMUSG00000052229 +619319 4932430I15Rik MGI:MGI:3588223 +619320 4930527B05Rik MGI:MGI:3588273 +619321 9530052E02Rik MGI:MGI:3588277|Ensembl:ENSMUSG00000096938 +619322 F830104G03Rik MGI:MGI:3588185 +619323 F730021E23Rik MGI:MGI:3588252 +619324 C130040N14Rik MGI:MGI:3588257 +619325 I920046F24Rik MGI:MGI:3588260 +619326 9130409I23Rik MGI:MGI:3588271|Ensembl:ENSMUSG00000038768|Vega:OTTMUSG00000050463 +619327 G630093K05Rik MGI:MGI:3588274 +619328 I730028E13Rik MGI:MGI:3588278|Ensembl:ENSMUSG00000110998 +619329 F420015M19Rik MGI:MGI:3588283 +619330 F830210D05Rik MGI:MGI:3588228 +619331 Zfp551 MGI:MGI:3588205|Ensembl:ENSMUSG00000034071|Vega:OTTMUSG00000027122 +619332 4933416C03Rik MGI:MGI:3588269|Ensembl:ENSMUSG00000074734 +619333 F930026P19Rik MGI:MGI:3588282 +619334 Xlr4e-ps MGI:MGI:3574182 +619355 Gm6083 MGI:MGI:3779550 +619371 Stxbp3-ps MGI:MGI:3586869 +619372 Klra17c MGI:MGI:3588585 +619441 Tnfsfm13 MGI:MGI:3845075|Ensembl:ENSMUSG00000018752|Vega:OTTMUSG00000035115 +619517 Esp1 MGI:MGI:3645915|Ensembl:ENSMUSG00000073396|Vega:OTTMUSG00000028873 +619547 Rpl34-ps1 MGI:MGI:3704270 +619548 Defb42 MGI:MGI:3033850|Ensembl:ENSMUSG00000054763|Vega:OTTMUSG00000020960 +619557 4932431L22Rik MGI:MGI:3588255|Ensembl:ENSMUSG00000104442 +619596 Gm6085 MGI:MGI:3646770 +619597 Gal3st2c MGI:MGI:3646771|Ensembl:ENSMUSG00000073608|Vega:OTTMUSG00000048694 +619601 Gm6087 MGI:MGI:3644467 +619605 Zcchc17 MGI:MGI:1919955|Ensembl:ENSMUSG00000028772|Vega:OTTMUSG00000009593 +619612 Gm6088 MGI:MGI:3647646 +619645 Gm6089 MGI:MGI:3647070 +619653 Gm6091 MGI:MGI:3648068 +619665 Klf14 MGI:MGI:3577024|Ensembl:ENSMUSG00000073209|Vega:OTTMUSG00000014454 +619677 4930529C04Rik MGI:MGI:1922392|Ensembl:ENSMUSG00000086377 +619688 Gm6092 MGI:MGI:3643525 +619697 Vmn2r116 MGI:MGI:3646674|Ensembl:ENSMUSG00000090966|Vega:OTTMUSG00000039966 +619715 Gm6093 MGI:MGI:3648840|Ensembl:ENSMUSG00000112963 +619719 6430590A07Rik MGI:MGI:3648839 +619734 Gm6096 MGI:MGI:3649053 +619743 Igkv4-56 MGI:MGI:4439916|IMGT/GENE-DB:IGKV4-56 +619750 Mif-ps3 MGI:MGI:103164 +619764 Gm6098 MGI:MGI:3779552 +619775 Vmn2r-ps134 MGI:MGI:3761694 +619780 Gm6100 MGI:MGI:3644987 +619785 Gm6101 MGI:MGI:3644986 +619788 Vmn2r117 MGI:MGI:3648766|Ensembl:ENSMUSG00000091407|Vega:OTTMUSG00000039968 +619806 Igkv4-51 MGI:MGI:5009829|IMGT/GENE-DB:IGKV4-51 +619808 1700010L04Rik MGI:MGI:1916583 +619824 Igkv12-49 MGI:MGI:5009830|IMGT/GENE-DB:IGKV12-49 +619829 Gm6104 MGI:MGI:3648587 +619833 Ighv1-69 MGI:MGI:4439632|IMGT/GENE-DB:IGHV1-69 +619842 Gm12633 MGI:MGI:3650768|Ensembl:ENSMUSG00000080756 +619846 Igkv5-48 MGI:MGI:3642817|IMGT/GENE-DB:IGKV5-48 +619863 Gm6105 MGI:MGI:3649051 +619864 Vmn2r-ps94 MGI:MGI:3761346 +619876 Gm6108 MGI:MGI:3779553 +619883 Gm6109 MGI:MGI:3643032 +619886 Ighv1-71 MGI:MGI:3643033|IMGT/GENE-DB:IGHV1-71 +619900 Rps27a-ps2 MGI:MGI:3643614 +619906 Gm11920 MGI:MGI:3650119 +619909 Gm6112 MGI:MGI:3643615 +619914 Gm6113 MGI:MGI:3646518 +619916 Ighv1-72 MGI:MGI:4439633 +619917 Gm6114 MGI:MGI:3646517 +619937 Hmgb1-ps10 MGI:MGI:96116 +619941 Gm13770 MGI:MGI:3651719 +619945 Gm6116 MGI:MGI:3644088|Ensembl:ENSMUSG00000072874 +619959 Gm6117 MGI:MGI:3647032 +619960 Igkv12-41 MGI:MGI:4439772|IMGT/GENE-DB:IGKV12-41 +619973 Gm12538 MGI:MGI:3650715 +619974 Igkv5-40-1 MGI:MGI:5009831|IMGT/GENE-DB:IGKV5-40-1 +619980 Gm6119 MGI:MGI:3644547 +619991 Gm6121 MGI:MGI:3779555|Ensembl:ENSMUSG00000080725|Vega:OTTMUSG00000017486 +619994 Ighv1-77 MGI:MGI:4439670|IMGT/GENE-DB:IGHV1-77 +619996 Gm6122 MGI:MGI:3647510 +620009 Gm6123 MGI:MGI:3647047 +620016 Gm12669 MGI:MGI:3651683|Ensembl:ENSMUSG00000100863 +620017 Igkv5-39 MGI:MGI:2686255|IMGT/GENE-DB:IGKV5-39 +620018 Gm6124 MGI:MGI:3779556 +620025 Gm6125 MGI:MGI:3644052 +620050 Igkv12-38 MGI:MGI:4439614|IMGT/GENE-DB:IGKV12-38 +620078 C130026I21Rik MGI:MGI:3612702|Ensembl:ENSMUSG00000052477|Vega:OTTMUSG00000029174 +620079 Gm17751 MGI:MGI:5009832|Ensembl:ENSMUSG00000100553 +620088 Igkv18-36 MGI:MGI:4439613|IMGT/GENE-DB:IGKV18-36 +620095 Vmn2r-ps137 MGI:MGI:3761341 +620105 Igkv1-35 MGI:MGI:4439612|IMGT/GENE-DB:IGKV1-35 +620110 Gm13666 MGI:MGI:3651577 +620119 Gm6128 MGI:MGI:3645269 +620121 4930555K19Rik MGI:MGI:1922612 +620126 Igkv8-34 MGI:MGI:4949914|IMGT/GENE-DB:IGKV8-34 +620132 Gm6129 MGI:MGI:3645100 +620137 Mrgprb13 MGI:MGI:3033193 +620140 Ighv1-83 MGI:MGI:3648939|IMGT/GENE-DB:IGHV1-83 +620143 Gm6132 MGI:MGI:3648940 +620147 Pvrig-ps MGI:MGI:3648938 +620155 Gm6133 MGI:MGI:3647029 +620156 Gm13409 MGI:MGI:3651609 +620189 Gm14371 MGI:MGI:3651566 +620191 Igkv6-29 MGI:MGI:4439616|IMGT/GENE-DB:IGKV6-29 +620205 Gm6135 MGI:MGI:3643755 +620213 Gm6136 MGI:MGI:3646897 +620228 Gm6137 MGI:MGI:3643498 +620235 Siglec15 MGI:MGI:3646642|Ensembl:ENSMUSG00000091055|Vega:OTTMUSG00000037043 +620240 Igkv8-26 MGI:MGI:4439869|IMGT/GENE-DB:IGKV8-26 +620246 Gpr52 MGI:MGI:3643278 +620248 Gm6139 MGI:MGI:3643279 +620253 Dcpp3 MGI:MGI:3646420|Ensembl:ENSMUSG00000057417 +620269 Gm12641 MGI:MGI:3649567 +620283 Gm6140 MGI:MGI:3649056 +620290 Gm6141 MGI:MGI:3646012 +620292 Cntnap5c MGI:MGI:3646013|Ensembl:ENSMUSG00000038048 +620297 Trav6n-6 MGI:MGI:3642618|IMGT/GENE-DB:TRAV6N-6 +620313 Gm6142 MGI:MGI:3644670 +620316 BC002189 MGI:MGI:3642300 +620325 Rpl13-ps4 MGI:MGI:3648077 +620340 Rpl9-ps5 MGI:MGI:3648306 +620376 Gm6145 MGI:MGI:3779559 +620382 Gm6146 MGI:MGI:3648737 +620387 Igkv8-22 MGI:MGI:5009833|IMGT/GENE-DB:IGKV8-22 +620390 Gm6147 MGI:MGI:3645494 +620393 Alkal1 MGI:MGI:3645495|Ensembl:ENSMUSG00000087247|Vega:OTTMUSG00000050239 +620395 Tdgf1-ps1 MGI:MGI:107367 +620400 Igkv8-21 MGI:MGI:1330840|IMGT/GENE-DB:IGKV8-21 +620401 Gm16442 MGI:MGI:3645807|Ensembl:ENSMUSG00000096152|Vega:OTTMUSG00000038184 +620408 Gm6149 MGI:MGI:3643044 +620417 Gm6150 MGI:MGI:3779560|Ensembl:ENSMUSG00000111901 +620419 Zfp963 MGI:MGI:4867078|Ensembl:ENSMUSG00000092260|Vega:OTTMUSG00000037163 +620444 Gm6152 MGI:MGI:3648859 +620454 Gm6153 MGI:MGI:3645798 +620480 Gm6155 MGI:MGI:3643981 +620497 Gm6157 MGI:MGI:3779561 +620499 Gm6158 MGI:MGI:3779562 +620521 Gm6159 MGI:MGI:3644323 +620537 Vmn1r94 MGI:MGI:3647287|Ensembl:ENSMUSG00000094011|Vega:OTTMUSG00000038186 +620542 Gm6161 MGI:MGI:3644104 +620544 Gm13576 MGI:MGI:3649302 +620551 LOC620551 Ensembl:ENSMUSG00000094172 +620559 Gm12366 MGI:MGI:3649557 +620562 Gm12152 MGI:MGI:3649296 +620570 Gm6162 MGI:MGI:3647648 +620574 Gm6164 MGI:MGI:3647652|Ensembl:ENSMUSG00000094298|Vega:OTTMUSG00000038188 +620583 Gm9804 MGI:MGI:3704387 +620592 Tmem28 MGI:MGI:3648377|Ensembl:ENSMUSG00000071719|Vega:OTTMUSG00000018147 +620615 Gm6167 MGI:MGI:3649163 +620627 Sult2a-ps2 MGI:MGI:3645687 +620631 Ttc30a2 MGI:MGI:3700200|Ensembl:ENSMUSG00000075272|Vega:OTTMUSG00000015167 +620639 LOC620639 Ensembl:ENSMUSG00000094855 +620641 Vmn2r-ps66 MGI:MGI:3758012 +620648 Gm6169 MGI:MGI:3646298 +620659 Gm6170 MGI:MGI:3643368 +620661 Itpa-ps1 MGI:MGI:3613363 +620665 Gm6171 MGI:MGI:3646093 +620672 Vmn2r67 MGI:MGI:3643129|Ensembl:ENSMUSG00000095664|Vega:OTTMUSG00000037874 +620678 Gm12174 MGI:MGI:3651722|Ensembl:ENSMUSG00000080776 +620683 Vmn2r-ps68 MGI:MGI:3761309 +620693 Gm6173 MGI:MGI:3648296 +620695 Gm13889 MGI:MGI:3652053|Ensembl:ENSMUSG00000087006|Vega:OTTMUSG00000014994 +620697 Vmn2r68 MGI:MGI:3648297|Ensembl:ENSMUSG00000096861|Vega:OTTMUSG00000037877 +620709 Lcn6 MGI:MGI:3045364|Ensembl:ENSMUSG00000045684|Vega:OTTMUSG00000012517 +620725 Gm6174 MGI:MGI:3647626 +620734 Gm6175 MGI:MGI:3644440 +620736 Gm6176 MGI:MGI:3644439|Ensembl:ENSMUSG00000096283|Vega:OTTMUSG00000045835 +620750 Gm6177 MGI:MGI:3643753 +620758 Vmn1r160 MGI:MGI:3779564|Ensembl:ENSMUSG00000094931|Vega:OTTMUSG00000038040 +620760 2900079G21Rik MGI:MGI:1920268|Ensembl:ENSMUSG00000087038 +620771 Gm16060 MGI:MGI:3783246 +620772 Gm6180 MGI:MGI:3643972 +620779 Gm12695 MGI:MGI:3650206|Ensembl:ENSMUSG00000078639|Vega:OTTMUSG00000008003 +620782 Gm6181 MGI:MGI:3646422 +620790 Gm14443 MGI:MGI:3652324 +620807 Mup6 MGI:MGI:3650962|Ensembl:ENSMUSG00000078689|Vega:OTTMUSG00000007423 +620837 Gm6184 MGI:MGI:3648764 +620839 Gm6185 MGI:MGI:3648765 +620853 Gm6187 MGI:MGI:3648954 +620858 Gm13539 MGI:MGI:3651926|Ensembl:ENSMUSG00000085484 +620865 Gm14845 MGI:MGI:3704515 +620877 Gm12933 MGI:MGI:3651147 +620882 Mup-ps2 MGI:MGI:3651073 +620883 Gm12696 MGI:MGI:3649288 +620899 Gm6189 MGI:MGI:3643154 +620913 Gm12185 MGI:MGI:3652173|Ensembl:ENSMUSG00000048852|Vega:OTTMUSG00000005523 +620915 Gm6190 MGI:MGI:3643523 +620928 Vmn2r73 MGI:MGI:3646433|Ensembl:ENSMUSG00000070458|Vega:OTTMUSG00000037826 +620934 Ube2nl MGI:MGI:3643295 +620942 Mup-ps6 MGI:MGI:3647161 +620946 Gm6192 MGI:MGI:3779569 +620949 Dph3b-ps MGI:MGI:3647154 +620966 Gm6194 MGI:MGI:3704094 +620982 Mup-ps7 MGI:MGI:3651245 +620986 Gm6195 MGI:MGI:3647661 +620997 Mup-ps4 MGI:MGI:3782916 +621001 Rpl19-ps6 MGI:MGI:3644218 +621017 Gm6197 MGI:MGI:3647151 +621020 Gm6198 MGI:MGI:3644461 +621054 Tpm3-rs7 MGI:MGI:99705 +621080 AI429214 MGI:MGI:2142538|Ensembl:ENSMUSG00000074384|Vega:OTTMUSG00000061068 +621093 Mup-ps13 MGI:MGI:3802118 +621096 Vmn2r-ps86 MGI:MGI:3761331 +621100 Rpl27-ps3 MGI:MGI:3646174 +621102 Gm6200 MGI:MGI:3644054 +621103 Gm6201 MGI:MGI:3779571 +621119 Rps11-ps1 MGI:MGI:3644744 +621127 Mup-ps14 MGI:MGI:3651980 +621146 Gm13803 MGI:MGI:3651056 +621149 Gm6203 MGI:MGI:3645773 +621155 Gm6204 MGI:MGI:3649038 +621156 Apoo-ps MGI:MGI:3649039 +621171 Gm13604 MGI:MGI:3652203 +621203 Gm6205 MGI:MGI:3779572 +621205 Gm6206 MGI:MGI:3644890 +621227 Gm12365 MGI:MGI:3649559 +621228 Gm15697 MGI:MGI:3783138 +621239 Nhlrc4 MGI:MGI:3687200|Ensembl:ENSMUSG00000090113|Vega:OTTMUSG00000033452 +621246 Gm6207 MGI:MGI:3645256 +621269 Actg-ps1 MGI:MGI:87907 +621304 Gm6209 MGI:MGI:3643374 +621306 Gm6210 MGI:MGI:3643375 +621312 Gm6211 MGI:MGI:3646534|Ensembl:ENSMUSG00000091577 +621322 Pramel MGI:MGI:3643636 +621324 Gm6212 MGI:MGI:3643635 +621335 Gm6213 MGI:MGI:3646754|Ensembl:ENSMUSG00000109827 +621343 Gm6214 MGI:MGI:3643859 +621352 Gm6215 MGI:MGI:3647031 +621353 Gm6216 MGI:MGI:3647030 +621362 Gm6217 MGI:MGI:3644079 +621363 Gm6218 MGI:MGI:3643171 +621364 Frg2f4 MGI:MGI:3644083 +621377 Aprt-ps MGI:MGI:88062 +621380 Gm6221 MGI:MGI:3648721 +621381 Gm6222 MGI:MGI:3648722 +621386 Gm13809 MGI:MGI:3649440 +621407 Gm9970 MGI:MGI:3642876 +621414 Gm6223 MGI:MGI:3646615 +621427 Gm10244 MGI:MGI:3642504|Ensembl:ENSMUSG00000068601 +621430 Vmn2r79 MGI:MGI:3646882|Ensembl:ENSMUSG00000090362|Vega:OTTMUSG00000037782 +621442 Gm14414 MGI:MGI:3652253 +621446 Gm6226 MGI:MGI:3643254 +621458 Rpl23a-ps6 MGI:MGI:3652320 +621462 Gm6227 MGI:MGI:3643479 +621467 Gm6228 MGI:MGI:3643481 +621477 Gm6230 MGI:MGI:3646402 +621486 Rpl31-ps2 MGI:MGI:3779573 +621487 Frg2f9 MGI:MGI:3779574 +621495 Krtap28-10 MGI:MGI:3779575 +621499 Frg2f10 MGI:MGI:3779576 +621501 Gm6235 MGI:MGI:3648491 +621504 Gm6236 MGI:MGI:3779577 +621510 Vmn1r129 MGI:MGI:3645471|Ensembl:ENSMUSG00000094879|Vega:OTTMUSG00000038166 +621542 Gm6238 MGI:MGI:3648913 +621549 Gm11783 MGI:MGI:3649458 +621561 Vmn1r127 MGI:MGI:3779578|Ensembl:ENSMUSG00000093890|Vega:OTTMUSG00000038164 +621562 Gm6240 MGI:MGI:3648708 +621573 Gm12700 MGI:MGI:3651090 +621579 Gm6242 MGI:MGI:3645659 +621580 Gm13308 MGI:MGI:3650431|Ensembl:ENSMUSG00000094695 +621588 Gm12943 MGI:MGI:3650497 +621595 Krtap19-7 MGI:MGI:3644653 +621603 Aldh3b2 MGI:MGI:2147613|Ensembl:ENSMUSG00000075296|Vega:OTTMUSG00000033682 +621605 Gbp2-ps MGI:MGI:3647028 +621612 Gm12960 MGI:MGI:3651525 +621614 Gm6244 MGI:MGI:3643858 +621628 Cldn20 MGI:MGI:3646757|Ensembl:ENSMUSG00000091530 +621629 Gm6245 MGI:MGI:3646756 +621663 Gm6247 MGI:MGI:3646308 +621666 Gm6248 MGI:MGI:3644899 +621677 Gm6249 MGI:MGI:3644248|Ensembl:ENSMUSG00000110101 +621697 Rpl32l MGI:MGI:3644747 +621699 Gm6252 MGI:MGI:3644748 +621705 Gemin6-ps MGI:MGI:3645567 +621710 Gm6254 MGI:MGI:3648838 +621740 B020010K11Rik MGI:MGI:3612155 +621763 Gm6257 MGI:MGI:3645370 +621809 Gm6260 MGI:MGI:3645891|Ensembl:ENSMUSG00000105279 +621815 Gm6261 MGI:MGI:3648928 +621818 Gm9785 MGI:MGI:3641899 +621823 Psme2b MGI:MGI:1341073|Ensembl:ENSMUSG00000078153|Vega:OTTMUSG00000005530 +621824 Gm6263 MGI:MGI:3646097 +621832 Nutf2-ps2 MGI:MGI:3704482 +621835 Gm6264 MGI:MGI:3779580 +621837 Gm6265 MGI:MGI:3649160 +621842 Gm6266 MGI:MGI:3646310 +621852 Rhox3f MGI:MGI:3770277|Ensembl:ENSMUSG00000095510|Vega:OTTMUSG00000017155 +621858 Gm11805 MGI:MGI:3649544 +621875 A530040E14Rik MGI:MGI:3612703 +621880 Gm12387 MGI:MGI:3651413 +621893 Hist2h2ab MGI:MGI:2448314|Ensembl:ENSMUSG00000063689|Vega:OTTMUSG00000042076 +621901 Gm6268 MGI:MGI:3644556 +621903 Dppa3-ps MGI:MGI:3645894 +621953 Gm6270 MGI:MGI:3647282 +621961 Anp32b-ps1 MGI:MGI:3651262 +621967 Gm6272 MGI:MGI:3643871 +621968 Trbv1 MGI:MGI:98594|IMGT/GENE-DB:TRBV1 +621976 Tmem170b MGI:MGI:3647046|Ensembl:ENSMUSG00000087370 +621983 Gm6274 MGI:MGI:3645367 +621984 Gm6275 MGI:MGI:3645368 +621988 Gm6276 MGI:MGI:3645369 +621998 Gm6277 MGI:MGI:3779583 +622000 Gm6278 MGI:MGI:3644862 +622019 Gm11780 MGI:MGI:3650485 +622032 Vmn1r167 MGI:MGI:3644421|Ensembl:ENSMUSG00000090715|Vega:OTTMUSG00000038000 +622037 B930092H01Rik MGI:MGI:4437738|Ensembl:ENSMUSG00000111658 +622052 Frg2f8 MGI:MGI:3648470 +622054 LOC622054 - +622070 Gm15133 MGI:MGI:3705170|Ensembl:ENSMUSG00000087175 +622075 Gm6283 MGI:MGI:3648260 +622082 Gm6284 MGI:MGI:3643970 +622098 Gm6285 MGI:MGI:3647132 +622102 Gm6286 MGI:MGI:3646153 +622116 Gm6287 MGI:MGI:3643197 +622117 Triml2 MGI:MGI:3642989|Ensembl:ENSMUSG00000091490|Vega:OTTMUSG00000061167 +622124 Gm20750 MGI:MGI:5434106|Ensembl:ENSMUSG00000104401 +622127 Cyp3a57 MGI:MGI:3646373|Ensembl:ENSMUSG00000070419|Vega:OTTMUSG00000030608 +622129 Gm6288 MGI:MGI:3646376 +622139 Clca4c-ps MGI:MGI:3643218|Ensembl:ENSMUSG00000074196 +622146 Gm6290 MGI:MGI:3645757 +622152 Gm6291 MGI:MGI:3648803 +622159 Gm6292 MGI:MGI:3648806 +622167 Gm12718 MGI:MGI:3651516|Ensembl:ENSMUSG00000086136 +622175 E430024I08Rik MGI:MGI:3649010 +622178 Gm6293 MGI:MGI:3649011 +622202 Rpl30-ps9 MGI:MGI:3648153 +622204 Gm6296 MGI:MGI:3648150 +622208 Gm6297 MGI:MGI:3779584 +622213 Gm6298 MGI:MGI:3645163 +622222 Vmn1r175 MGI:MGI:3648367|Ensembl:ENSMUSG00000095632|Vega:OTTMUSG00000038009 +622229 Gm6300 MGI:MGI:3648364 +622236 Rpl27-ps1 MGI:MGI:3645348 +622251 A26c2 MGI:MGI:3644757 +622263 Gm6303 MGI:MGI:3647931 +622266 Gm15007 MGI:MGI:3647930 +622268 Gm6304 MGI:MGI:3647929 +622271 Gm6305 MGI:MGI:3644967 +622282 Gm6306 MGI:MGI:3646938 +622283 Mir1a-1hg MGI:MGI:3649026 +622297 Gm6308 MGI:MGI:3648854 +622301 Rhox2h MGI:MGI:3713490|Ensembl:ENSMUSG00000079627|Vega:OTTMUSG00000017156 +622304 F730311O21Rik MGI:MGI:3643355|Ensembl:ENSMUSG00000100658 +622306 Gm6309 MGI:MGI:3643357|Ensembl:ENSMUSG00000096798|Vega:OTTMUSG00000037037 +622307 5830473C10Rik MGI:MGI:1923342|Ensembl:ENSMUSG00000070690|Vega:OTTMUSG00000055489 +622311 Rhox2-ps MGI:MGI:3646282 +622313 Gm6311 MGI:MGI:3644735 +622315 Gm12717 MGI:MGI:3650774 +622318 Gm6312 MGI:MGI:3646278 +622319 Gm6313 MGI:MGI:3644722|Ensembl:ENSMUSG00000070995 +622320 Kctd21 MGI:MGI:3643121|Ensembl:ENSMUSG00000044952|Vega:OTTMUSG00000029536 +622334 Gm12900 MGI:MGI:3650387 +622335 Gm6314 MGI:MGI:3646082 +622336 Rps7-ps1 MGI:MGI:3779585 +622339 Gm6316 MGI:MGI:3646088 +622356 Gm13888 MGI:MGI:3651975 +622365 Gm6317 MGI:MGI:3648927 +622367 Rpl31-ps5 MGI:MGI:3648926 +622384 Fabp5l2 MGI:MGI:3644282 +622402 Akr1c12 MGI:MGI:1351661|Ensembl:ENSMUSG00000021211|Vega:OTTMUSG00000027685 +622404 Ccdc107 Ensembl:ENSMUSG00000028461|Vega:OTTMUSG00000006917 +622408 Mcidas MGI:MGI:3648807|Ensembl:ENSMUSG00000074651 +622425 Gm6321 MGI:MGI:3648569 +622432 Gm6322 MGI:MGI:3645541 +622434 Arhgef26 MGI:MGI:1918053|Ensembl:ENSMUSG00000036885|Vega:OTTMUSG00000031219 +622446 Ptma-ps1 MGI:MGI:3644252 +622459 Gm12216 MGI:MGI:3650088|Ensembl:ENSMUSG00000081769|Vega:OTTMUSG00000005650 +622469 Gm12966 MGI:MGI:3652043 +622473 Ripply1 MGI:MGI:3614797|Ensembl:ENSMUSG00000072945|Vega:OTTMUSG00000018733 +622474 Smok3b MGI:MGI:3615348|Ensembl:ENSMUSG00000079156|Vega:OTTMUSG00000032570 +622480 Spocd1 MGI:MGI:3652045|Ensembl:ENSMUSG00000028784 +622481 Gm15784 MGI:MGI:3783226 +622485 4930526A20Rik MGI:MGI:3612449 +622486 Smok3c MGI:MGI:3647925|Ensembl:ENSMUSG00000075598|Vega:OTTMUSG00000032454 +622491 Gm11221 MGI:MGI:3651633 +622494 Gm6325 MGI:MGI:3644961 +622509 Gm6327 MGI:MGI:3646646 +622512 Gm6328 MGI:MGI:3643500 +622523 Gm6329 MGI:MGI:3646898|Ensembl:ENSMUSG00000110231 +622527 Gm14879 MGI:MGI:3646901 +622531 Gm6330 MGI:MGI:3643757 +622551 Gm6331 MGI:MGI:3643973 +622552 Gm20751 MGI:MGI:5434107|Ensembl:ENSMUSG00000110016 +622553 Gm6332 MGI:MGI:3648790 +622554 Majin MGI:MGI:1923913|Ensembl:ENSMUSG00000024786|Vega:OTTMUSG00000018618 +622561 Gm9771 MGI:MGI:3642065 +622567 Gm6333 MGI:MGI:3647384 +622568 Gm6334 MGI:MGI:3647382 +622570 Gm6335 MGI:MGI:3644202 +622589 Gm6336 MGI:MGI:3647630 +622592 Gm14398 MGI:MGI:3650079 +622629 Gm10318 MGI:MGI:3704118|Ensembl:ENSMUSG00000071195 +622640 Gm6337 MGI:MGI:3646283|Ensembl:ENSMUSG00000091882|Vega:OTTMUSG00000036198 +622645 Tmem200c MGI:MGI:3646281|Ensembl:ENSMUSG00000095407 +622655 Rpsa-ps2 MGI:MGI:3643356 +622657 Gm6340 MGI:MGI:3643354 +622665 Ccdc17 Ensembl:ENSMUSG00000034035|Vega:OTTMUSG00000009402 +622673 Gm6341 MGI:MGI:3643600 +622675 Zfp827 MGI:MGI:2444807|Ensembl:ENSMUSG00000071064|Vega:OTTMUSG00000031393 +622683 Gm6342 MGI:MGI:3645065 +622699 Gm12569 MGI:MGI:3650740 +622701 Gm6343 MGI:MGI:3647371 +622707 Gm6344 MGI:MGI:3779586 +622708 Gm6345 MGI:MGI:3647370|Ensembl:ENSMUSG00000096964 +622719 Gm6346 MGI:MGI:3644199 +622727 Rpl7a-ps10 MGI:MGI:3647131 +622728 Ighv1-75 MGI:MGI:4439735|IMGT/GENE-DB:IGHV1-75 +622731 Gm6348 MGI:MGI:3643967 +622733 Olfr764-ps1 MGI:MGI:3030598 +622737 Gm6350 MGI:MGI:3643969 +622744 Gm6351 MGI:MGI:3647817|Ensembl:ENSMUSG00000072821|Vega:OTTMUSG00000033800 +622745 Gm6352 MGI:MGI:3647816 +622746 Gm6353 MGI:MGI:3647819 +622757 Gm6354 MGI:MGI:3644642 +622781 Gm6356 MGI:MGI:3646390 +622794 Gm6358 MGI:MGI:3643237 +622795 Rps2-ps7 MGI:MGI:3643238 +622803 Gm6360 MGI:MGI:3643019 +622810 Gm6361 MGI:MGI:3646180 +622811 Gm12418 MGI:MGI:3650582 +622812 Gm6362 MGI:MGI:3644102 +622832 Gm6363 MGI:MGI:3645989 +622845 Gm6365 MGI:MGI:3643502 +622870 Gm6366 MGI:MGI:3646411 +622894 Gm6367 MGI:MGI:3704106|Ensembl:ENSMUSG00000096742|Vega:OTTMUSG00000049361 +622901 Gm6368 MGI:MGI:3644537 +622921 Gm6369 MGI:MGI:3644758 +622924 Gm6370 MGI:MGI:3779587|Ensembl:ENSMUSG00000096527|Vega:OTTMUSG00000055159 +622931 Gm10021 MGI:MGI:3704419 +622935 Krtap20-2 MGI:MGI:1916148|Ensembl:ENSMUSG00000091039 +622956 Gm6373 MGI:MGI:3647018 +622958 Gm6374 MGI:MGI:3647016 +622962 Gm6375 MGI:MGI:3644303 +622973 Gm6376 MGI:MGI:3647257 +622976 Gm6377 MGI:MGI:3647255|Ensembl:ENSMUSG00000048621|Vega:OTTMUSG00000018342 +622978 Gm6378 MGI:MGI:3647253 +623003 Gm13914 MGI:MGI:3650988 +623006 Gm6382 MGI:MGI:3646438 +623030 Gm6386 MGI:MGI:3643067 +623031 Gm13910 MGI:MGI:3651143 +623045 Rpl36-ps7 MGI:MGI:3649699 +623046 Fscb MGI:MGI:3646964|Ensembl:ENSMUSG00000043060 +623064 Gm6390 MGI:MGI:3779589 +623078 Gm8108 MGI:MGI:3779783 +623094 Gm6392 MGI:MGI:3644256 +623112 Stmn1-rs2 MGI:MGI:96741 +623114 Gm6394 MGI:MGI:3648319 +623115 Gm11488 MGI:MGI:3650705 +623121 Ifi213 MGI:MGI:3695276|Ensembl:ENSMUSG00000073491|Vega:OTTMUSG00000033987 +623122 Gm11877 MGI:MGI:3652029 +623123 Gm6395 MGI:MGI:3645295 +623131 Prr19 MGI:MGI:3648539|Ensembl:ENSMUSG00000058741|Vega:OTTMUSG00000058246 +623138 Gm6397 MGI:MGI:3648542 +623143 Gm6399 MGI:MGI:3645514 +623151 Gm14886 MGI:MGI:3648773 +623166 Prr23a1 MGI:MGI:3645743|Ensembl:ENSMUSG00000091080|Vega:OTTMUSG00000048332 +623168 Gm6401 MGI:MGI:3645739 +623169 Gm6402 MGI:MGI:3645740 +623172 Gm6403 MGI:MGI:3648997 +623174 Rpl34-ps2 MGI:MGI:3648994 +623186 Prr23a2 MGI:MGI:3645937|Ensembl:ENSMUSG00000063058|Vega:OTTMUSG00000048333 +623191 Gm6407 MGI:MGI:3642965 +623197 Gm11237 MGI:MGI:3702292|Ensembl:ENSMUSG00000094116|Vega:OTTMUSG00000000282 +623198 Gm6408 MGI:MGI:3779591|Ensembl:ENSMUSG00000096344|Vega:OTTMUSG00000055154 +623205 Gm11189 MGI:MGI:3650984 +623208 Gm6409 MGI:MGI:3643184 +623223 Gm6410 MGI:MGI:3643419 +623230 Tmem200b MGI:MGI:3646343|Ensembl:ENSMUSG00000070720 +623241 Gm6411 MGI:MGI:3643659 +623242 Rps2-ps8 MGI:MGI:3779592 +623257 Gm11400 MGI:MGI:3705645 +623269 Gm13414 MGI:MGI:3652154 +623270 Gm15130 MGI:MGI:3705238 +623272 Gm11757 MGI:MGI:3702097|Ensembl:ENSMUSG00000096750|Vega:OTTMUSG00000004012 +623273 Alms1-ps2 MGI:MGI:3779593|Ensembl:ENSMUSG00000090098 +623279 Dok6 MGI:MGI:3639495|Ensembl:ENSMUSG00000073514|Vega:OTTMUSG00000033317 +623281 Gm11756 MGI:MGI:3702095|Ensembl:ENSMUSG00000093962|Vega:OTTMUSG00000004010 +623286 Gm6415 MGI:MGI:3648526 +623301 Gm13961 MGI:MGI:3650627 +623312 Gm6416 MGI:MGI:3779595 +623325 Gm13349 MGI:MGI:3649966 +623331 D16Ertd727e MGI:MGI:1289219 +623337 Vmn2r-ps34 MGI:MGI:3761516 +623341 Gm6418 MGI:MGI:3647565 +623346 Gm6419 MGI:MGI:3647564 +623355 Rpl7a-ps9 MGI:MGI:3783074 +623356 Gm6420 MGI:MGI:3644588 +623365 Gm6421 MGI:MGI:3647311 +623374 Gm6423 MGI:MGI:3779596 +623380 Vmn2r-ps1 MGI:MGI:3757942 +623402 Gm6425 MGI:MGI:3646016 +623409 Gm6426 MGI:MGI:3646017 +623412 Gm6427 MGI:MGI:3649064 +623414 Gm6428 MGI:MGI:3649065 +623428 Gm6429 MGI:MGI:3645793 +623430 Gm6430 MGI:MGI:3648857 +623444 Gm14628 MGI:MGI:3644462 +623448 Gm13408 MGI:MGI:3649613 +623453 Gm13669 MGI:MGI:3651174 +623459 Faiml MGI:MGI:3647754|Ensembl:ENSMUSG00000096316|Vega:OTTMUSG00000048432 +623466 Gm6433 MGI:MGI:3645394 +623474 Rad54b MGI:MGI:3605986|Ensembl:ENSMUSG00000078773|Vega:OTTMUSG00000004520 +623475 Gm6434 MGI:MGI:3648424 +623483 Gm13196 MGI:MGI:3651918 +623488 Ppp1r2-ps4 MGI:MGI:3645199 +623503 Prlh MGI:MGI:3644668|Ensembl:ENSMUSG00000090550|Vega:OTTMUSG00000048409 +623505 Gm6436 MGI:MGI:3644667 +623516 Gm6437 MGI:MGI:3647846 +623519 Gm6438 MGI:MGI:3647845 +623529 Gm11255 MGI:MGI:3649873 +623534 Nme9 MGI:MGI:4359686 +623554 Gm6439 MGI:MGI:3647442 +623568 Gm6440 MGI:MGI:3644482 +623583 Olfr1293-ps MGI:MGI:3031127 +623591 Gm6441 MGI:MGI:3646924 +623601 Gm6443 MGI:MGI:3646734 +623647 Gm12221 MGI:MGI:3649330 +623661 Lipt1 MGI:MGI:3645211|Ensembl:ENSMUSG00000037216|Vega:OTTMUSG00000022093 +623671 Gm11841 MGI:MGI:3651164 +623672 Gm6444 MGI:MGI:3648226 +623678 Gm14653 MGI:MGI:3648224 +623688 Gm6445 MGI:MGI:3779598 +623697 Gm6446 MGI:MGI:3643050 +623706 Gm13651 MGI:MGI:3649524 +623713 Gm15057 MGI:MGI:3647203 +623726 A430085M09Rik MGI:MGI:3647836 +623731 Gm6447 MGI:MGI:3646963 +623734 Vmn2r85 MGI:MGI:3646965|Ensembl:ENSMUSG00000092048|Vega:OTTMUSG00000038223 +623781 Gm14137 MGI:MGI:3651144|Ensembl:ENSMUSG00000055926|Vega:OTTMUSG00000015762 +623783 X75261 MGI:MGI:3641709 +623796 Gm12504 MGI:MGI:3651567|Ensembl:ENSMUSG00000084274 +623798 Gm6450 MGI:MGI:3648082 +623804 Gm6451 MGI:MGI:3648305 +623809 Gm6452 MGI:MGI:3648304 +623810 Gm9750 MGI:MGI:3642669 +623830 Cyp2b19-ps MGI:MGI:3644897 +623849 Gm6455 MGI:MGI:3648736|Ensembl:ENSMUSG00000091422 +623859 Rps2-ps11 MGI:MGI:3648819 +623867 Gm6457 MGI:MGI:3648519 +623872 Gm6458 MGI:MGI:3645274 +623875 Gm1135 - +623898 Gm6460 MGI:MGI:3644247|Ensembl:ENSMUSG00000091903 +623913 Gm6461 MGI:MGI:3643881 +623924 Gm6462 MGI:MGI:3647053 +623935 Gm6463 MGI:MGI:3644114 +623954 Gm10493 MGI:MGI:3644330 +623995 Gm6464 MGI:MGI:3642951 +623998 Gm6465 MGI:MGI:3642949 +624037 Gm6467 MGI:MGI:3645284 +624049 Gm6468 MGI:MGI:3646666 +624056 Ctsm-ps2 MGI:MGI:3643776 +624083 Gm15753 MGI:MGI:3783195 +624086 A230045G11Rik MGI:MGI:3646202 +624088 Gm13436 MGI:MGI:3651005 +624096 Gm6470 MGI:MGI:3643280 +624121 Gm6471 MGI:MGI:3648397 +624124 Gm6472 MGI:MGI:3648396 +624138 Gm6473 MGI:MGI:3645176 +624140 Gm6474 MGI:MGI:3648182 +624144 Gm6475 MGI:MGI:3648186 +624153 H2afb2 MGI:MGI:3644980|Ensembl:ENSMUSG00000082482|Vega:OTTMUSG00000024449 +624159 Gm6476 MGI:MGI:3644981 +624165 Gm6477 MGI:MGI:3647945 +624168 Gm12241 MGI:MGI:3649718 +624180 Gm6478 MGI:MGI:3647766 +624183 Gm6479 MGI:MGI:3647767 +624187 Gm6480 MGI:MGI:3647765 +624191 Gm6482 MGI:MGI:3644578 +624198 Gm6483 MGI:MGI:3644574 +624219 Angptl8 MGI:MGI:3643534|Ensembl:ENSMUSG00000047822|Vega:OTTMUSG00000062317 +624223 Gm13688 MGI:MGI:3652062 +624224 Clrn2 MGI:MGI:3646230|Ensembl:ENSMUSG00000049530|Vega:OTTMUSG00000053976 +624245 Speer4e MGI:MGI:2668871|Ensembl:ENSMUSG00000091255|Vega:OTTMUSG00000036595 +624251 Gm6485 MGI:MGI:3644007 +624254 Gm6486 MGI:MGI:3644005 +624260 Gm6488 MGI:MGI:3646683 +624262 Gm6489 MGI:MGI:3646684 +624275 Gm10307 MGI:MGI:3642371 +624277 Gm6490 MGI:MGI:3779600 +624284 Gm6491 MGI:MGI:3644773 +624286 Cfhr3 MGI:MGI:3647418 +624295 LOC624295 - +624310 Gm6492 MGI:MGI:3644796 +624311 Gm6493 MGI:MGI:3644797 +624335 Gm6494 MGI:MGI:3644988 +624341 Olfr856-ps1 MGI:MGI:3030690 +624348 Gm6496 MGI:MGI:3647560 +624362 Gm6497 MGI:MGI:3647772 +624367 Gm6498 MGI:MGI:3647773|Ensembl:ENSMUSG00000063885 +624378 Gm6499 MGI:MGI:3644585 +624388 Gm6500 MGI:MGI:3648842 +624395 Gm6501 MGI:MGI:3645570 +624403 Gm12626 MGI:MGI:3650563 +624421 Gm6502 MGI:MGI:3779601|Ensembl:ENSMUSG00000095718|Vega:OTTMUSG00000055725 +624424 Gm12612 MGI:MGI:3650136 +624430 Gm12444 MGI:MGI:3650375 +624433 Gm6503 MGI:MGI:3644902 +624438 Gm10819 MGI:MGI:3642135 +624439 Scgb2b15 MGI:MGI:3644904|Ensembl:ENSMUSG00000097972|Vega:OTTMUSG00000043620 +624446 Gm6505 MGI:MGI:3648080 +624454 Gm6506 MGI:MGI:3645107 +624465 Gm12420 MGI:MGI:3652148 +624483 Gm6507 MGI:MGI:3645279 +624507 Gm6509 MGI:MGI:3779602 +624512 Vmn2r33 MGI:MGI:3757694|Ensembl:ENSMUSG00000096691|Vega:OTTMUSG00000037839 +624519 Gm6510 MGI:MGI:3645799 +624549 Gm29683 MGI:MGI:5588842|Ensembl:ENSMUSG00000109097 +624568 Gm6512 MGI:MGI:3643049 +624574 Rap1a-ps2 MGI:MGI:3651938 +624582 Morf4l1-ps1 MGI:MGI:3612158 +624584 Scgb2b10 MGI:MGI:3643785 +624605 Gm12245 MGI:MGI:3649494 +624652 Gm13474 MGI:MGI:3652316 +624662 Gm6517 MGI:MGI:3643656 +624672 Gm6518 MGI:MGI:3646789 +624681 Btnl6 MGI:MGI:1932038|Ensembl:ENSMUSG00000092618 +624684 Gm6520 MGI:MGI:3645184 +624685 Gm6521 MGI:MGI:3645185 +624696 Gm6522 MGI:MGI:3648401 +624698 Gm6523 MGI:MGI:3779604 +624701 Gm12497 MGI:MGI:3650111 +624710 Gm6524 MGI:MGI:3648756|Ensembl:ENSMUSG00000110177 +624713 Gm6525 MGI:MGI:3648757 +624717 Gm6526 MGI:MGI:3648758 +624759 Gm20752 MGI:MGI:5434108|Ensembl:ENSMUSG00000106053 +624765 Vmn2r80 MGI:MGI:3646321|Ensembl:ENSMUSG00000091888|Vega:OTTMUSG00000038140 +624772 LOC624772 - +624784 Gm9855 MGI:MGI:3704357 +624814 Gm12251 MGI:MGI:3652216 +624845 Vmn2r82 MGI:MGI:3646522|Ensembl:ENSMUSG00000091468|Vega:OTTMUSG00000038172 +624855 Cks1brt MGI:MGI:3643620|Ensembl:ENSMUSG00000062687|Vega:OTTMUSG00000061409 +624860 Gm12253 MGI:MGI:3651568|Ensembl:ENSMUSG00000058287|Vega:OTTMUSG00000005737 +624862 Gm6532 MGI:MGI:3646742 +624863 Gm6533 MGI:MGI:3646743 +624866 Lekr1 MGI:MGI:3645902|Ensembl:ENSMUSG00000074579|Vega:OTTMUSG00000021979 +624893 Gm6536 MGI:MGI:3644948 +624906 Gm14928 MGI:MGI:3648477 +624910 Rgs21 MGI:MGI:3645243|Ensembl:ENSMUSG00000098509|Vega:OTTMUSG00000044613 +624925 Gm6538 MGI:MGI:3648270 +624931 LOC624931 - +624936 Pou5f1-rs8 MGI:MGI:101886 +624957 H2afb3 MGI:MGI:3644875|Ensembl:ENSMUSG00000083616|Vega:OTTMUSG00000018509 +624960 Gm6540 MGI:MGI:3647824 +624966 Gm6541 MGI:MGI:3647825 +624979 Gm6542 MGI:MGI:3644649 +625004 Gm6543 MGI:MGI:3644322 +625018 C4a MGI:MGI:98320 +625026 Gm10048 MGI:MGI:3644560 +625029 Vmn2r83 MGI:MGI:3644559|Ensembl:ENSMUSG00000091381|Vega:OTTMUSG00000038173 +625031 Gpr31a MGI:MGI:1354370 +625033 Gm13713 MGI:MGI:3650490 +625046 Gm6545 MGI:MGI:3643874 +625048 Gm6546 MGI:MGI:3643872 +625050 Vmn1r-ps32 MGI:MGI:3646782 +625054 Gm6548 MGI:MGI:3644071 +625057 Gm6550 MGI:MGI:3646786 +625060 Gm6551 MGI:MGI:3644103 +625068 Vmn2r84 MGI:MGI:3643367|Ensembl:ENSMUSG00000070601|Vega:OTTMUSG00000038222 +625074 Gm6552 MGI:MGI:3647048 +625094 Gm13461 MGI:MGI:3650103 +625098 Slc38a6 MGI:MGI:3648156|Ensembl:ENSMUSG00000044712|Vega:OTTMUSG00000032835 +625102 Gm6553 MGI:MGI:3649067 +625109 Vmn2r86 MGI:MGI:3649066|Ensembl:ENSMUSG00000092162|Vega:OTTMUSG00000038224 +625110 Gm6554 MGI:MGI:3646019 +625115 Gm6555 MGI:MGI:3646021 +625121 Gm6556 MGI:MGI:3647197 +625123 Gm6557 MGI:MGI:3779606 +625125 Gm6558 MGI:MGI:3779607 +625131 Vmn2r87 MGI:MGI:3645796|Ensembl:ENSMUSG00000091511|Vega:OTTMUSG00000038225 +625132 Gm12599 MGI:MGI:3651469 +625167 Gm6559 MGI:MGI:3643041|Ensembl:ENSMUSG00000107660 +625174 Gm6560 MGI:MGI:3646204 +625175 1700028E10Rik MGI:MGI:1916713|Ensembl:ENSMUSG00000097321 +625181 Gm6562 MGI:MGI:3643759 +625193 Gm6563 MGI:MGI:3646907 +625210 Gm14625 MGI:MGI:3705849 +625219 Gm6564 MGI:MGI:3647928 +625222 Gm15520 MGI:MGI:3782967 +625237 Gm6566 MGI:MGI:3647745|Ensembl:ENSMUSG00000113918 +625243 Gm6567 MGI:MGI:3779609|Ensembl:ENSMUSG00000108383 +625249 Gpx4 MGI:MGI:104767|Ensembl:ENSMUSG00000075706|Vega:OTTMUSG00000019111 +625253 Gm6568 MGI:MGI:3647518 +625276 Gm6569 MGI:MGI:3647277 +625281 Gm6570 MGI:MGI:3644100 +625285 H2-Q3 MGI:MGI:95932 +625286 Tmem236 MGI:MGI:1919309|Ensembl:ENSMUSG00000061531|Vega:OTTMUSG00000011407 +625298 Rps13-ps1 MGI:MGI:3647042 +625305 Gm6574 MGI:MGI:3643499 +625310 Gm6575 MGI:MGI:3646645 +625311 Gm6576 MGI:MGI:3646644 +625321 Trim30e-ps1 MGI:MGI:4821258|Ensembl:ENSMUSG00000073929 +625328 H3f3c MGI:MGI:3650546 +625335 Gm13311 MGI:MGI:3651093 +625336 Rpl36-ps8 MGI:MGI:3650480 +625342 Gm13315 MGI:MGI:3651096 +625347 Gm6578 MGI:MGI:3643037|Ensembl:ENSMUSG00000057223 +625349 Gm6579 MGI:MGI:3643038 +625353 Vmn2r35 MGI:MGI:3646200|Ensembl:ENSMUSG00000096399|Vega:OTTMUSG00000037853 +625354 Gm13549 MGI:MGI:3651027 +625360 BC147527 MGI:MGI:4840510|Ensembl:ENSMUSG00000094796 +625377 Gm6580 MGI:MGI:3646421 +625403 Gm13998 MGI:MGI:3651215 +625405 Gm13015 MGI:MGI:3651767 +625409 Gm6581 MGI:MGI:3648298 +625421 C230062I16Rik MGI:MGI:2442417 +625424 Gm6583 MGI:MGI:3648511|Ensembl:ENSMUSG00000051503|Vega:OTTMUSG00000023503 +625436 Gm6584 MGI:MGI:3779611 +625446 Gm6586 MGI:MGI:3648729 +625457 Gm6587 MGI:MGI:3645486 +625462 Gm11888 MGI:MGI:3651111 +625464 Gm6588 MGI:MGI:3648937|Ensembl:ENSMUSG00000072722|Vega:OTTMUSG00000054332 +625473 Gm6590 MGI:MGI:3645685 +625476 Gm6591 MGI:MGI:3645686 +625480 Gm6592 MGI:MGI:3647394|Ensembl:ENSMUSG00000079699|Vega:OTTMUSG00000016841 +625495 Gm6593 MGI:MGI:3644209 +625508 Gm14596 MGI:MGI:3705870 +625514 Gm6594 MGI:MGI:3643873 +625530 Usp17le MGI:MGI:107697|Ensembl:ENSMUSG00000043073|Vega:OTTMUSG00000060831 +625534 Ska2l-ps MGI:MGI:3643639 +625540 Gm6598 MGI:MGI:3646314|Ensembl:ENSMUSG00000107143 +625548 Gm6599 MGI:MGI:3646311 +625558 Gm6600 MGI:MGI:3643376 +625574 Tgif2-ps1 MGI:MGI:3649223 +625580 Vmn2r48 MGI:MGI:3647749|Ensembl:ENSMUSG00000095914|Vega:OTTMUSG00000038505 +625585 Gm6602 MGI:MGI:3779614|Ensembl:ENSMUSG00000104543 +625591 Cldn34c2 MGI:MGI:3644765|Ensembl:ENSMUSG00000095474 +625594 Gm6605 MGI:MGI:3644762 +625597 Gm6606 MGI:MGI:3644763 +625599 Gml MGI:MGI:3644767|Ensembl:ENSMUSG00000068349|Vega:OTTMUSG00000045156 +625603 Gm6607 MGI:MGI:3645371 +625605 Vmn2r49 MGI:MGI:3757933|Ensembl:ENSMUSG00000096180|Vega:OTTMUSG00000038506 +625608 Gm11950 MGI:MGI:3650313 +625631 Bloc1s2-ps MGI:MGI:3702045 +625638 Fam43b MGI:MGI:3651622|Ensembl:ENSMUSG00000078235|Vega:OTTMUSG00000009974 +625646 Rpl38-ps1 MGI:MGI:3649580 +625650 Gm10057 MGI:MGI:3710528|Ensembl:ENSMUSG00000096867|Vega:OTTMUSG00000019277 +625653 Gm6610 MGI:MGI:3648858 +625660 Gm6611 MGI:MGI:3645568 +625662 Ankrd31 MGI:MGI:5006716|Ensembl:ENSMUSG00000109561|Vega:OTTMUSG00000059356 +625672 Gm6612 MGI:MGI:3648604 +625690 Gm6613 MGI:MGI:3643042 +625713 Gm15140 MGI:MGI:3709336|Ensembl:ENSMUSG00000094592|Vega:OTTMUSG00000019256 +625716 Gm6614 MGI:MGI:3647159|Ensembl:ENSMUSG00000079263|Vega:OTTMUSG00000042482 +625721 Gm6615 MGI:MGI:3644221 +625729 Gm11957 MGI:MGI:3649800 +625730 Gm6616 MGI:MGI:3647406 +625732 Gm11893 MGI:MGI:3651418 +625752 Gm11270 MGI:MGI:3649599 +625753 Gm6618 MGI:MGI:3647645 +625758 Gm6619 MGI:MGI:3779616 +625760 Gm11956 MGI:MGI:3649806 +625767 Gm6620 MGI:MGI:3644671 +625775 Gm6621 MGI:MGI:3647848 +625780 Gm6622 MGI:MGI:3644900 +625781 Hmgb1l MGI:MGI:3054046 +625785 Gm6623 MGI:MGI:3644901 +625796 Fam136b-ps MGI:MGI:3648078 +625801 Gm6625 MGI:MGI:3647663 +625810 Gm6626 MGI:MGI:3805016 +625811 Gm6627 MGI:MGI:3644486 +625815 Gm13352 MGI:MGI:3651070 +625823 Vmn1r1 MGI:MGI:3647849|Ensembl:ENSMUSG00000091013|Vega:OTTMUSG00000038238 +625835 Gm6630 MGI:MGI:3644672 +625850 Gm11166 MGI:MGI:3810119 +625853 Olfr1077-ps1 MGI:MGI:3030911 +625861 Gm13573 MGI:MGI:3652221 +625863 Mageb16-ps2 MGI:MGI:3701602 +625868 Gm6631 MGI:MGI:3644892 +625870 Gm6632 MGI:MGI:3644251 +625881 Gm6633 MGI:MGI:3779618 +625901 Gm6634 MGI:MGI:3643829|Ensembl:ENSMUSG00000097252 +625912 Tpm3-rs2 MGI:MGI:99710 +625917 Rpl31-ps20 MGI:MGI:3644512 +625929 Rps19-ps4 MGI:MGI:3645935 +625931 Gm6637 MGI:MGI:3642957 +625941 Gm6638 MGI:MGI:3779619 +625958 Gm12611 MGI:MGI:3650135 +625963 Gm6639 MGI:MGI:3779620|Ensembl:ENSMUSG00000105662 +625969 Gm6640 MGI:MGI:3646353 +625977 Gm13019 MGI:MGI:3652310 +625989 Gm6641 MGI:MGI:3645310 +625995 Gm6642 MGI:MGI:3648551 +625997 Gm6643 MGI:MGI:3648552 +626000 Ccnd3-ps MGI:MGI:1100505 +626009 Gm6644 MGI:MGI:3644951 +626034 Gm6645 MGI:MGI:3647900 +626048 Rps12-ps16 MGI:MGI:3645883 +626049 Gm20753 MGI:MGI:5434109|Ensembl:ENSMUSG00000101583 +626053 Gm6647 MGI:MGI:3647714 +626055 Gm15645 MGI:MGI:3783089 +626058 E330020D12Rik MGI:MGI:3761270 +626061 Gm6649 MGI:MGI:3779621 +626067 Gm6650 MGI:MGI:3644295 +626075 Gm6651 MGI:MGI:3647491 +626082 Gm20754 MGI:MGI:5434110|Ensembl:ENSMUSG00000103428 +626096 Gm6652 MGI:MGI:3647244 +626115 Gm6653 MGI:MGI:3647484 +626123 9130004C02Rik MGI:MGI:2444340 +626150 Gm12271 MGI:MGI:3650794 +626175 Gm6654 MGI:MGI:3648118 +626180 Gm6655 MGI:MGI:3645297 +626215 Gm6657 MGI:MGI:3645257|Ensembl:ENSMUSG00000099418|Vega:OTTMUSG00000047062 +626231 Gm6658 MGI:MGI:3645470 +626259 Rps6-ps1 MGI:MGI:3809093 +626274 Gm6660 MGI:MGI:3645872 +626275 A930012L18Rik MGI:MGI:2442887|Ensembl:ENSMUSG00000097610 +626288 Gm13140 MGI:MGI:3649297 +626299 Vmn1r194 MGI:MGI:3651596|Ensembl:ENSMUSG00000069297|Vega:OTTMUSG00000000480 +626305 Scgb1b7 MGI:MGI:3643480|Ensembl:ENSMUSG00000078759|Vega:OTTMUSG00000037051 +626309 Gm6663 MGI:MGI:3643477 +626315 Gm6664 MGI:MGI:3646403 +626316 Zfp987 MGI:MGI:3702694|Ensembl:ENSMUSG00000066009|Vega:OTTMUSG00000010173 +626325 Gm12274 MGI:MGI:3651758 +626327 Gm6665 MGI:MGI:3643253 +626333 Gm6667 MGI:MGI:3779622 +626342 Gm11972 MGI:MGI:3650055 +626347 Igkv3-4 MGI:MGI:1330855|IMGT/GENE-DB:IGKV3-4 +626348 Gm6668 MGI:MGI:3643961 +626358 Gm6669 MGI:MGI:3646884 +626359 Wdr93 MGI:MGI:3646885|Ensembl:ENSMUSG00000039099|Vega:OTTMUSG00000029045 +626367 Rpl31-ps15 MGI:MGI:3643738 +626373 Rpl23a-ps11 MGI:MGI:3646618 +626390 Gm6673 MGI:MGI:3645556 +626391 Zfp951 MGI:MGI:2441896|Ensembl:ENSMUSG00000072774|Vega:OTTMUSG00000047246 +626397 Vmn1r12 MGI:MGI:3645555|Ensembl:ENSMUSG00000057981|Vega:OTTMUSG00000039908 +626410 Gm20755 MGI:MGI:5434111|Ensembl:ENSMUSG00000106461 +626415 4930467E23Rik MGI:MGI:1923056|Ensembl:ENSMUSG00000096265|Vega:OTTMUSG00000062138 +626419 Gm11981 MGI:MGI:3650697|Ensembl:ENSMUSG00000086808 +626436 Vmn2r-ps31 MGI:MGI:3761512 +626439 Gm14639 MGI:MGI:3641909 +626456 Gm6676 MGI:MGI:3646103 +626461 Gm6677 MGI:MGI:3648953 +626474 Gm6679 MGI:MGI:3648541 +626479 Gm6680 MGI:MGI:3645908 +626480 Gm13170 MGI:MGI:3651095 +626482 Wsb2-ps MGI:MGI:3649891 +626489 Gm12871 MGI:MGI:3649219 +626503 Gm6681 MGI:MGI:3643996 +626513 Gm14052 MGI:MGI:3650009 +626534 Gm6682 MGI:MGI:3647156 +626545 Trdv5 MGI:MGI:3704133|IMGT/GENE-DB:TRDV5 +626549 Gm6684 MGI:MGI:3643522 +626563 Gm14035 MGI:MGI:3650858 +626571 Gm6685 MGI:MGI:3704119 +626573 Gm6686 MGI:MGI:3646669 +626575 Gm6687 MGI:MGI:3646960 +626578 Gbp10 MGI:MGI:4359647|Ensembl:ENSMUSG00000105096|Vega:OTTMUSG00000053860 +626582 Vmn1r-ps12 MGI:MGI:3643065 +626583 Igkv3-2 MGI:MGI:1330850|IMGT/GENE-DB:IGKV3-2 +626596 Rgs22 MGI:MGI:3613651|Ensembl:ENSMUSG00000037627|Vega:OTTMUSG00000036995 +626605 Gm6689 MGI:MGI:3645828 +626615 Apol11a MGI:MGI:3649094|Ensembl:ENSMUSG00000091650 +626649 Vmn1r-ps14 MGI:MGI:3645438 +626652 Gm6693 MGI:MGI:3648678 +626659 Vmn1r-ps15 MGI:MGI:3648676 +626661 Gm10156 MGI:MGI:3642344 +626672 Gm6695 MGI:MGI:3648885 +626674 Olfr471 MGI:MGI:3030305 +626682 Defa28 MGI:MGI:3646688|Ensembl:ENSMUSG00000074434|Vega:OTTMUSG00000019896 +626683 Gm11362 MGI:MGI:3651391 +626693 Gm15713 MGI:MGI:3783155|Ensembl:ENSMUSG00000085499 +626700 Gm13041 MGI:MGI:3649499 +626708 Defa26 MGI:MGI:3630390|Ensembl:ENSMUSG00000060070|Vega:OTTMUSG00000019889 +626721 Cd63-ps MGI:MGI:105972 +626724 Vmn1r-ps19 MGI:MGI:3647074 +626740 Scgb2b30 MGI:MGI:3646832 +626746 Gm6704 MGI:MGI:3646833 +626785 Gm6705 MGI:MGI:3648191 +626797 Gm6706 MGI:MGI:3644992 +626802 Gm14322 MGI:MGI:3652185|Ensembl:ENSMUSG00000078864|Vega:OTTMUSG00000016321 +626828 Vmn1r31 MGI:MGI:3649162|Ensembl:ENSMUSG00000093379|Vega:OTTMUSG00000039995 +626832 Gm6710 MGI:MGI:3779623|Ensembl:ENSMUSG00000078887|Vega:OTTMUSG00000016202 +626834 Klk13 MGI:MGI:3615275|Ensembl:ENSMUSG00000054046|Vega:OTTMUSG00000058307 +626841 Gm6711 MGI:MGI:3648932 +626848 Zfp971 MGI:MGI:1261426|Ensembl:ENSMUSG00000074519|Vega:OTTMUSG00000016324 +626854 Gm38396 MGI:MGI:5618688 +626858 Gm6713 MGI:MGI:3645890 +626870 Gm11992 MGI:MGI:3651127|Ensembl:ENSMUSG00000040978|Vega:OTTMUSG00000005148 +626877 Gm14405 MGI:MGI:3649815 +626878 Gm6714 MGI:MGI:3645675 +626887 Gm11993 MGI:MGI:3651126 +626888 Rpl36-ps4 MGI:MGI:3644086 +626889 Gm13106 MGI:MGI:3651761 +626897 Gm6717 MGI:MGI:3647267 +626903 Rpl31-ps21 MGI:MGI:3644652 +626904 Gm20756 MGI:MGI:5434112|Ensembl:ENSMUSG00000106799 +626912 Gm6719 MGI:MGI:3647632 +626922 Gm13101 MGI:MGI:3650204 +626940 Gm6721 MGI:MGI:3645077 +626942 Vmn2r90 MGI:MGI:3645076|Ensembl:ENSMUSG00000092120|Vega:OTTMUSG00000039012 +626943 Pramef17 MGI:MGI:3650199|Ensembl:ENSMUSG00000078509|Vega:OTTMUSG00000010438 +626950 Gm6722 MGI:MGI:3648053 +626952 Gm6723 MGI:MGI:3648054 +626959 Gm12292 MGI:MGI:3649414 +626970 Scgb2b21 MGI:MGI:3648283|Ensembl:ENSMUSG00000099900|Vega:OTTMUSG00000045855 +626985 Gm6726 MGI:MGI:3643751 +626995 Gm13128 MGI:MGI:3651261|Ensembl:ENSMUSG00000078508|Vega:OTTMUSG00000010552 +627003 Gm6727 MGI:MGI:3643658 +627004 Gm12770 MGI:MGI:3649644 +627009 Pramef20 MGI:MGI:3712553|Ensembl:ENSMUSG00000073721|Vega:OTTMUSG00000010547 +627022 Gm6728 MGI:MGI:3643418 +627035 Gm6729 MGI:MGI:3646339 +627045 Gm6730 MGI:MGI:3643177 +627049 Zfp800 MGI:MGI:1889334|Ensembl:ENSMUSG00000039841|Vega:OTTMUSG00000021280 +627060 Fpr-rs5 MGI:MGI:1278316 +627074 Gm15236 MGI:MGI:3645927 +627079 Scgb2b25-ps MGI:MGI:3649900 +627081 Xlr5b MGI:MGI:3574109|Ensembl:ENSMUSG00000072479|Vega:OTTMUSG00000017646 +627085 Gm13124 MGI:MGI:3652194|Ensembl:ENSMUSG00000078506|Vega:OTTMUSG00000010546 +627094 Gm6731 MGI:MGI:3645328 +627108 Gm6732 MGI:MGI:3648429 +627110 Tubb2a-ps2 MGI:MGI:2145100 +627111 Vmn2r92 MGI:MGI:3761352|Ensembl:ENSMUSG00000091350|Vega:OTTMUSG00000039016 +627119 Gm6733 MGI:MGI:3645402 +627132 Vmn2r93 MGI:MGI:3645591|Ensembl:ENSMUSG00000079698|Vega:OTTMUSG00000039018 +627139 Gm6734 MGI:MGI:3645590 +627160 Gm11687 MGI:MGI:3652085 +627166 Gm15801 MGI:MGI:3779625 +627171 Trav1 MGI:MGI:3651476|IMGT/GENE-DB:TRAV1 +627187 Gm14350 MGI:MGI:3650416 +627189 Gm6736 MGI:MGI:3643048 +627191 Syndig1l MGI:MGI:2685107|Ensembl:ENSMUSG00000071234 +627214 Fam196a MGI:MGI:3605068|Ensembl:ENSMUSG00000073805|Vega:OTTMUSG00000060266 +627232 Gm6740 MGI:MGI:3643503 +627235 Gm6741 MGI:MGI:3643504 +627244 Gm12003 MGI:MGI:3651520 +627245 Rps7-ps2 MGI:MGI:3646014 +627264 Btbd35f28 MGI:MGI:3709183|Ensembl:ENSMUSG00000094307|Vega:OTTMUSG00000016407 +627268 Gm15232 MGI:MGI:3705117|Ensembl:ENSMUSG00000084806 +627270 Igf1os MGI:MGI:3841250 +627273 Trav7d-5 MGI:MGI:3649422|IMGT/GENE-DB:TRAV7D-5 +627280 Vmn1r90 MGI:MGI:3612342|Ensembl:ENSMUSG00000100586|Vega:OTTMUSG00000042506 +627299 Gm6743 MGI:MGI:3648616 +627302 Gm14092 MGI:MGI:3651965 +627311 Gm6744 MGI:MGI:3648299 +627312 Gm11759 MGI:MGI:3651480 +627317 Gm6745 MGI:MGI:3648302 +627324 Trav9-1 MGI:MGI:3650356|IMGT/GENE-DB:TRAV9-1 +627342 Gm6746 MGI:MGI:3645488 +627352 Morf4l1b MGI:MGI:3648734 +627367 Vmn2r97 MGI:MGI:3645271|Ensembl:ENSMUSG00000091491|Vega:OTTMUSG00000039025 +627371 Gm6749 MGI:MGI:3648518 +627375 Gm6750 MGI:MGI:3779628 +627394 Trav6d-3 MGI:MGI:3650097|IMGT/GENE-DB:TRAV6D-3 +627395 Gm6751 MGI:MGI:3647438 +627412 Gm14373 MGI:MGI:3651800 +627420 Gm6754 MGI:MGI:3645755 +627424 Gm6755 MGI:MGI:3645758 +627427 Gm6756 MGI:MGI:3647509|Ensembl:ENSMUSG00000063514 +627430 Gm6757 MGI:MGI:3648801 +627455 Gm6758 MGI:MGI:3643216 +627466 Gm6759 MGI:MGI:3646151 +627470 Gm6760 MGI:MGI:3643199|Ensembl:ENSMUSG00000079579|Vega:OTTMUSG00000017604 +627479 Vmn2r8 MGI:MGI:3642986|Ensembl:ENSMUSG00000090961|Vega:OTTMUSG00000039851 +627480 Gm6762 MGI:MGI:3643568 +627488 Gm6763 MGI:MGI:3643573|Ensembl:ENSMUSG00000097427|Vega:OTTMUSG00000042979 +627503 Gm6764 MGI:MGI:3644641 +627511 Gm6765 MGI:MGI:3647818 +627525 Gm13768 MGI:MGI:3651239 +627537 Vmn2r100 MGI:MGI:3648026|Ensembl:ENSMUSG00000091859|Vega:OTTMUSG00000039761 +627543 Gm6767 MGI:MGI:3645053 +627557 Gm6768 MGI:MGI:3648259 +627569 Vmn2r12 MGI:MGI:3761377|Ensembl:ENSMUSG00000090688|Vega:OTTMUSG00000039861 +627576 Vmn2r101 MGI:MGI:3648468|Ensembl:ENSMUSG00000094892|Vega:OTTMUSG00000039762 +627577 Gm6771 MGI:MGI:3648467 +627583 Gm12664 MGI:MGI:3651281 +627585 Gm13034 MGI:MGI:3650252 +627607 Lrrc74a MGI:MGI:3646959|Ensembl:ENSMUSG00000059114 +627608 Gm6773 MGI:MGI:3646956 +627618 Vmn2r-ps122 MGI:MGI:3761606 +627624 Gm6776 MGI:MGI:3647201 +627626 Ptchd4 MGI:MGI:1920485|Ensembl:ENSMUSG00000042256 +627636 Vmn2r103 MGI:MGI:3644032|Ensembl:ENSMUSG00000091771|Vega:OTTMUSG00000039765 +627664 Vmn2r-ps125 MGI:MGI:3761611 +627696 Gm12019 MGI:MGI:3650974 +627716 Gm12020 MGI:MGI:3650978 +627717 Gm6781 MGI:MGI:3644510 +627733 Gm15653 MGI:MGI:3783097 +627734 Gm6783 MGI:MGI:3644277 +627737 Rpl22-ps1 MGI:MGI:3644276 +627741 Gm6785 MGI:MGI:3646975 +627743 Vmn2r105 MGI:MGI:3646973|Ensembl:ENSMUSG00000091670|Vega:OTTMUSG00000039773 +627751 Gm6786 MGI:MGI:3644036 +627775 Xlr5e-ps MGI:MGI:3574181 +627777 Trav17 MGI:MGI:3702128|IMGT/GENE-DB:TRAV17 +627782 Gm6787 MGI:MGI:3646481|Ensembl:ENSMUSG00000086404 +627788 Gm6788 MGI:MGI:3646480 +627792 Gm6789 MGI:MGI:3643581 +627798 Tpt1-ps5 MGI:MGI:2664999 +627800 Gm20757 MGI:MGI:5434113|Ensembl:ENSMUSG00000098040 +627805 Vmn2r108 MGI:MGI:3643822|Ensembl:ENSMUSG00000091805|Vega:OTTMUSG00000039781 +627813 Trdv1 MGI:MGI:3649381|IMGT/GENE-DB:TRDV1 +627814 Vmn2r109 MGI:MGI:3646711|Ensembl:ENSMUSG00000090572|Vega:OTTMUSG00000039783 +627821 Epp13 MGI:MGI:3643580|Ensembl:ENSMUSG00000053367|Vega:OTTMUSG00000031401 +627828 Gm6793 MGI:MGI:3643578|Ensembl:ENSMUSG00000092086 +627833 Gm6794 MGI:MGI:3646483 +627835 Rps12-ps19 MGI:MGI:3652063 +627852 Gm6796 MGI:MGI:3646260 +627853 Gm6797 MGI:MGI:3646261 +627857 Gm6798 MGI:MGI:3646258 +627858 Gm6799 MGI:MGI:3646265 +627860 Cyp2d37-ps MGI:MGI:3721937 +627866 Gm6801 MGI:MGI:3643101 +627871 Gm6802 MGI:MGI:3646076 +627872 Dnah7a MGI:MGI:2685838|Ensembl:ENSMUSG00000096141|Vega:OTTMUSG00000046899 +627873 Gm6803 MGI:MGI:3779631 +627884 Vmn1r-ps144 MGI:MGI:3649147 +627888 Gm6806 MGI:MGI:3649146 +627889 Gm6807 MGI:MGI:3649145 +627891 LOC627891 - +627895 Gm6808 MGI:MGI:3645881 +627897 Gm14037 MGI:MGI:3650852 +627901 Gm14419 MGI:MGI:3702410 +627912 Gm6809 MGI:MGI:3779633 +627914 Gm14430 MGI:MGI:3702412 +627924 Gm6811 MGI:MGI:3648804 +627927 Gm6812 MGI:MGI:3704138|Ensembl:ENSMUSG00000056815|Vega:OTTMUSG00000017747 +627939 Gm6813 MGI:MGI:3645759 +627962 Gm6815 MGI:MGI:3648348 +627967 Rps4l-ps MGI:MGI:3648347 +627975 Gm6818 MGI:MGI:3645331 +627983 Gm6819 MGI:MGI:3647711 +627984 Nlrp1c-ps MGI:MGI:3582962|Ensembl:ENSMUSG00000092528 +627985 Trmt112-ps2 MGI:MGI:3651720 +627987 Gm6820 MGI:MGI:3647709 +627995 Gm6821 MGI:MGI:3779634 +627998 Gm6822 MGI:MGI:3644721 +628002 Gm6823 MGI:MGI:3648161 +628004 Gm10561 MGI:MGI:3648163 +628006 Rpl18a-ps2 MGI:MGI:3648164 +628007 Gm6825 MGI:MGI:3648165 +628008 Fthl17-ps2 MGI:MGI:3648159 +628012 Gm16441 MGI:MGI:3646768 +628027 Igkv1-133 MGI:MGI:3648380|IMGT/GENE-DB:IGKV1-133 +628030 Gm6828 MGI:MGI:3645353 +628040 Gm6829 MGI:MGI:3648590 +628042 Rpl18a-ps3 MGI:MGI:3648591 +628048 Vmn2r-ps35 MGI:MGI:3757687 +628050 Gm6831 MGI:MGI:3645552 +628053 Gm14725 MGI:MGI:3705881 +628056 Igkv1-131 MGI:MGI:3645551|IMGT/GENE-DB:IGKV1-131 +628058 Gm6833 MGI:MGI:3645553 +628060 Gm14165 MGI:MGI:3650537 +628061 Rps13-ps4 MGI:MGI:3648822 +628062 Gm29684 MGI:MGI:5588843|Ensembl:ENSMUSG00000112481 +628072 Igkv14-130 MGI:MGI:3645770|IMGT/GENE-DB:IGKV14-130 +628081 Gm6838 MGI:MGI:3649030 +628098 Ighv5-12-4 MGI:MGI:3645977|IMGT/GENE-DB:IGHV5-12-4 +628100 Fbxo39 MGI:MGI:3505735|Ensembl:ENSMUSG00000070388|Vega:OTTMUSG00000006107 +628103 Gm14071 MGI:MGI:3652234 +628108 Gm12344 MGI:MGI:3649822 +628110 Gm14408 MGI:MGI:3651910 +628116 Gm6841 MGI:MGI:3646303 +628117 Gm6842 MGI:MGI:3646304 +628119 Anapc15-ps MGI:MGI:3646302 +628127 Igkv14-126 MGI:MGI:3643131|IMGT/GENE-DB:IGKV14-126 +628128 Vmn2r-ps41 MGI:MGI:3757868 +628133 Platr6 MGI:MGI:3779636 +628135 Gm6847 MGI:MGI:3646094 +628144 Igkv9-123 MGI:MGI:3643848|IMGT/GENE-DB:IGKV9-123 +628145 Zfp419 MGI:MGI:3643847 +628147 Gm2004 MGI:MGI:3780174 +628152 Gm6850 MGI:MGI:3646739 +628155 LOC628155 - +628161 Gm6851 MGI:MGI:3643618 +628176 Gm6852 MGI:MGI:3646520 +628185 Vmn2r112 MGI:MGI:3644292|Ensembl:ENSMUSG00000094921|Vega:OTTMUSG00000039900 +628189 Gm6853 MGI:MGI:3644291 +628205 LOC628205 - +628206 Igkv1-115 MGI:MGI:3644873|IMGT/GENE-DB:IGKV1-115 +628211 Gm6855 MGI:MGI:3648447 +628236 Lipo4 MGI:MGI:3779637|Ensembl:ENSMUSG00000079344 +628237 Gm6858 MGI:MGI:3647823 +628239 Gm14411 MGI:MGI:3649821 +628256 Gm6859 MGI:MGI:3647629 +628261 Bb1 - +628262 Gm6860 MGI:MGI:3643892 +628268 Igkv2-109 MGI:MGI:3642626|IMGT/GENE-DB:IGKV2-109 +628272 Igkv1-108 MGI:MGI:3644576|IMGT/GENE-DB:IGKV1-108 +628277 Gm6863 MGI:MGI:3647386 +628283 Igkv2-107 MGI:MGI:3645630|IMGT/GENE-DB:IGKV2-107 +628293 Igkv11-106 MGI:MGI:3648899|IMGT/GENE-DB:IGKV11-106 +628298 Gm14328 MGI:MGI:3651951 +628301 Gm11383 MGI:MGI:3649586 +628304 Gm6866 MGI:MGI:3646160 +628308 Zfp970 MGI:MGI:3652255|Ensembl:ENSMUSG00000078866|Vega:OTTMUSG00000016588 +628324 S100a2 MGI:MGI:3510999|Ensembl:ENSMUSG00000094018 +628327 Gm6867 MGI:MGI:3646385 +628338 Rpl23a-ps13 MGI:MGI:3643229 +628351 Gm6869 MGI:MGI:3643459 +628356 Gm6870 MGI:MGI:3643457 +628359 Gm6871 MGI:MGI:3643456 +628368 Vmn2r-ps37 MGI:MGI:3757696 +628372 Gm6872 MGI:MGI:3643699 +628388 Rpl3-ps2 MGI:MGI:3645345 +628398 Ighv6-4 MGI:MGI:3704120|IMGT/GENE-DB:IGHV6-4 +628403 Vmn2r-ps56 MGI:MGI:3757983 +628412 Gm6877 MGI:MGI:3644703 +628416 Gm6878 MGI:MGI:3644701 +628422 Vmn2r58 MGI:MGI:3647877|Ensembl:ENSMUSG00000090383|Vega:OTTMUSG00000037965 +628431 Hmgb1-rs17 MGI:MGI:104764 +628438 Hspe1-rs1 MGI:MGI:1935159 +628441 Rpl30-ps11 MGI:MGI:3642364 +628444 Vmn2r59 MGI:MGI:3643747|Ensembl:ENSMUSG00000092032|Vega:OTTMUSG00000037942 +628449 Rpl21-ps2 MGI:MGI:3647229 +628456 Gm6880 MGI:MGI:3644285|Ensembl:ENSMUSG00000079536|Vega:OTTMUSG00000019969 +628465 Gm6881 MGI:MGI:3647481 +628474 Gm15362 MGI:MGI:3707585 +628475 Gm6882 MGI:MGI:3645601|Ensembl:ENSMUSG00000109516|Vega:OTTMUSG00000045831 +628477 Gm6883 MGI:MGI:3644521 +628480 Gm6884 MGI:MGI:3646729 +628490 Vmn2r-ps60 MGI:MGI:3757993 +628495 Gm6885 MGI:MGI:3643835 +628498 Igkv13-78-1 MGI:MGI:3647961|IMGT/GENE-DB:IGKV13-78-1 +628503 Gm6887 MGI:MGI:3649086 +628515 Gm6888 MGI:MGI:3779638 +628516 Igkv4-73 MGI:MGI:3645825|IMGT/GENE-DB:IGKV4-73 +628518 Gm6890 MGI:MGI:3645826|Ensembl:ENSMUSG00000079532|Vega:OTTMUSG00000020731 +628521 Vmn1r-ps47 MGI:MGI:3648882 +628525 Vmn1r-ps48 MGI:MGI:3648881 +628537 Gm6893 MGI:MGI:3645616 +628541 Igkv4-69 MGI:MGI:3648668|IMGT/GENE-DB:IGKV4-69 +628551 Igkv12-67 MGI:MGI:3645399|IMGT/GENE-DB:IGKV12-67 +628564 Igkv13-64 MGI:MGI:5009834|IMGT/GENE-DB:IGKV13-64 +628571 Igkv4-63 MGI:MGI:3645235|IMGT/GENE-DB:IGKV4-63 +628573 Gm6897 MGI:MGI:3645236 +628580 Vmn1r68 MGI:MGI:3648262|Ensembl:ENSMUSG00000047031|Vega:OTTMUSG00000038515 +628586 Gm6899 MGI:MGI:3648261 +628596 Gm6900 MGI:MGI:3645052 +628614 Ighv1-34 MGI:MGI:4439659|IMGT/GENE-DB:IGHV1-34 +628627 Gm14519 MGI:MGI:3646740 +628637 Gm14758 MGI:MGI:3705810 +628664 Gm6902 MGI:MGI:3647238|Ensembl:ENSMUSG00000094682|Vega:OTTMUSG00000045841 +628676 Gm10139 MGI:MGI:3642815 +628681 Gm6903 MGI:MGI:3779639 +628686 D030068K23Rik MGI:MGI:3037424|Ensembl:ENSMUSG00000097393 +628693 Gm6904 MGI:MGI:3644962|Ensembl:ENSMUSG00000090881 +628696 Gm6905 MGI:MGI:3644964 +628697 Gm6906 MGI:MGI:3644963 +628705 Phf11c MGI:MGI:3648476|Ensembl:ENSMUSG00000091144|Vega:OTTMUSG00000043572 +628707 Gm14253 MGI:MGI:3650994 +628709 Gm10324 MGI:MGI:3642406|Ensembl:ENSMUSG00000095909 +628722 Vmn2r-ps98 MGI:MGI:3761350 +628726 Rpl26-ps6 MGI:MGI:3648682 +628737 Gm6909 MGI:MGI:3645442 +628746 Rybp-ps MGI:MGI:3648043 +628753 Gm12176 MGI:MGI:3651497 +628757 Gm6912 MGI:MGI:3644874 +628768 Gm6913 MGI:MGI:3648267 +628779 Hs3st4 MGI:MGI:1333792|Ensembl:ENSMUSG00000078591|Vega:OTTMUSG00000020328 +628781 Gm6916 MGI:MGI:3644024 +628801 Gm6918 MGI:MGI:3643700 +628808 Vmn2r-ps99 MGI:MGI:3761351 +628813 Gm11437 MGI:MGI:3650287|Ensembl:ENSMUSG00000051452|Vega:OTTMUSG00000000997 +628822 Gm6919 MGI:MGI:3648520 +628830 Gm12090 MGI:MGI:3650090 +628847 Gm6921 MGI:MGI:3644183 +628850 6030426L16Rik MGI:MGI:1924364 +628853 Vmn1r-ps53 MGI:MGI:3647358 +628854 Gm15517 MGI:MGI:3782964 +628855 Gm6923 MGI:MGI:3647357 +628856 Gm9909 MGI:MGI:3642124 +628870 Otogl MGI:MGI:3647600|Ensembl:ENSMUSG00000091455|Vega:OTTMUSG00000043359 +628877 Gm29685 MGI:MGI:5588844|Ensembl:ENSMUSG00000112910 +628883 Serpina3e-ps MGI:MGI:2182837 +628893 Cldn34-ps MGI:MGI:3645962 +628898 Gm6929 MGI:MGI:3645961 +628900 Serpina3i MGI:MGI:2182841|Ensembl:ENSMUSG00000079014|Vega:OTTMUSG00000035425 +628903 Gm6931 MGI:MGI:3645140 +628916 Serpina3l-ps MGI:MGI:2182857 +628919 Gm6934 MGI:MGI:3648115 +628923 Gm14744 MGI:MGI:3709306|Ensembl:ENSMUSG00000079522|Vega:OTTMUSG00000017866 +628924 Mszf81 - +628926 Gm16489 MGI:MGI:3642053 +628935 Gm14200 MGI:MGI:3651374 +628946 Vmn1r77 MGI:MGI:3779641|Ensembl:ENSMUSG00000095864|Vega:OTTMUSG00000038251 +628951 Gm6936 MGI:MGI:3779642 +628963 Mszf78 - +628976 Gm16458 MGI:MGI:3644776 +628991 Obp1b MGI:MGI:1277948|Ensembl:ENSMUSG00000067679|Vega:OTTMUSG00000017867 +628994 Gm6937 MGI:MGI:3647230 +629016 Zfp953 MGI:MGI:3612873|Ensembl:ENSMUSG00000098905|Vega:OTTMUSG00000036829 +629024 Gm6938 MGI:MGI:3648987|Ensembl:ENSMUSG00000087586 +629029 Gm6939 MGI:MGI:3782976 +629043 Gm6942 MGI:MGI:3643094 +629055 Gm6943 MGI:MGI:3645931 +629057 Gm6944 MGI:MGI:3645932 +629059 Fam124a MGI:MGI:3645930|Ensembl:ENSMUSG00000035184|Vega:OTTMUSG00000034680 +629079 Vmn2r56 MGI:MGI:3695438|Ensembl:ENSMUSG00000090762|Vega:OTTMUSG00000038271 +629081 Gm6946 MGI:MGI:3647908 +629091 Gm29686 MGI:MGI:5588845 +629101 Gm6947 MGI:MGI:3647350 +629114 Defb23 MGI:MGI:3644405|Ensembl:ENSMUSG00000074681|Vega:OTTMUSG00000029051 +629116 Rps24-ps3 MGI:MGI:3644407 +629121 Gm6949 MGI:MGI:3647122 +629133 Gm20472 MGI:MGI:5141937 +629141 Gm9999 MGI:MGI:3642801|Ensembl:ENSMUSG00000056509|Vega:OTTMUSG00000046199 +629147 Ctxn3 MGI:MGI:3642816|Ensembl:ENSMUSG00000069372|Vega:OTTMUSG00000061315 +629152 Gm6951 MGI:MGI:3643963 +629153 Gm6952 MGI:MGI:3643962 +629159 1700008J07Rik MGI:MGI:1916610|Ensembl:ENSMUSG00000101225 +629170 Gm14162 MGI:MGI:3649237 +629182 Gm6954 MGI:MGI:3648228 +629203 Sult2a3 MGI:MGI:3645873|Ensembl:ENSMUSG00000074375|Vega:OTTMUSG00000021845 +629204 Gm6956 MGI:MGI:3648219 +629206 Gm20758 MGI:MGI:5434114|Ensembl:ENSMUSG00000112533 +629219 Sult2a6 MGI:MGI:3648915|Ensembl:ENSMUSG00000070810|Vega:OTTMUSG00000021842 +629242 Gm6958 MGI:MGI:3779643 +629292 Gm6960 MGI:MGI:3643572 +629300 Gm6961 MGI:MGI:3644546 +629303 Heatr9 MGI:MGI:3650286|Ensembl:ENSMUSG00000018925|Vega:OTTMUSG00000000990 +629310 Rpl10-ps4 MGI:MGI:3647741 +629337 Gm6963 MGI:MGI:3647921 +629340 Gm6964 MGI:MGI:3644958 +629342 Rpl7a-ps4 MGI:MGI:3644959 +629359 Gm6967 MGI:MGI:3648147 +629364 Gm16372 MGI:MGI:3648102 +629372 Hmgb1-ps4 MGI:MGI:3768540 +629374 Mageb6-ps MGI:MGI:2148170 +629378 Dact3 MGI:MGI:3654828|Ensembl:ENSMUSG00000078794|Vega:OTTMUSG00000033325 +629383 Gm6969 MGI:MGI:3645320 +629389 Gm6970 MGI:MGI:3645322 +629393 Gm20759 MGI:MGI:5434115 +629419 Gm6973 MGI:MGI:3647797 +629436 Gm6974 MGI:MGI:3647986 +629448 Gm6975 MGI:MGI:3644403 +629471 Gm6977 MGI:MGI:3647597 +629480 Gm6978 MGI:MGI:3647254 +629481 Gm29687 MGI:MGI:5588846|Ensembl:ENSMUSG00000113550 +629499 Mroh8 MGI:MGI:3603828|Ensembl:ENSMUSG00000074627|Vega:OTTMUSG00000016166 +629502 LOC629502 - +629524 Olfr286 MGI:MGI:3030120 +629542 Gm14781 MGI:MGI:3712084|Ensembl:ENSMUSG00000064129|Vega:OTTMUSG00000017976 +629549 Gm6979 MGI:MGI:3779644 +629554 Gm6980 MGI:MGI:3779645 +629557 Gm6981 MGI:MGI:3646966 +629568 Gm6982 MGI:MGI:3643575 +629573 Gm6983 MGI:MGI:3646709 +629578 Cbx3-ps6 MGI:MGI:3646710 +629581 Gm6985 MGI:MGI:3644316 +629583 Gm6986 MGI:MGI:3645363 +629591 Gm6987 MGI:MGI:3647485 +629595 Gm6988 MGI:MGI:3647486 +629608 Gm6989 MGI:MGI:3645400 +629636 Gm11502 MGI:MGI:3652282 +629643 Mif-ps9 MGI:MGI:103166 +629652 Gm6991 MGI:MGI:3648225 +629655 Gm11448 MGI:MGI:3651347 +629656 Gm6992 MGI:MGI:3647975 +629667 Gm6993 MGI:MGI:3644833 +629678 Gm6994 MGI:MGI:3647788|Ensembl:ENSMUSG00000067973 +629684 Gm6995 MGI:MGI:3644599 +629709 Gm6997 MGI:MGI:3644027 +629732 Rps8-ps1 MGI:MGI:3647445 +629734 Gm6999 MGI:MGI:3647443 +629742 Gm7001 MGI:MGI:3646413 +629746 Gm29688 MGI:MGI:5588847 +629747 Spint3 MGI:MGI:3651470|Ensembl:ENSMUSG00000074596|Vega:OTTMUSG00000016288 +629750 Gm11517 MGI:MGI:3650064 +629754 Wfdc9 MGI:MGI:3652032|Ensembl:ENSMUSG00000074594|Vega:OTTMUSG00000001088 +629756 Wfdc10 MGI:MGI:3616889|Ensembl:ENSMUSG00000070529|Vega:OTTMUSG00000016289 +629758 Gm7002 MGI:MGI:3779646 +629761 Wfdc11 MGI:MGI:3651686|Ensembl:ENSMUSG00000078940|Vega:OTTMUSG00000016290 +629777 Zfp335os MGI:MGI:3649775 +629785 Gm7003 MGI:MGI:3643089|IMGT/GENE-DB:IGHV(III)-4 +629794 Gm7004 MGI:MGI:3646248 +629812 Ighv16-1 MGI:MGI:3643819|IMGT/GENE-DB:IGHV16-1 +629818 Ighv9-2 MGI:MGI:3643816|IMGT/GENE-DB:IGHV9-2 +629820 Gm7008 MGI:MGI:3647211|Ensembl:ENSMUSG00000035983|Vega:OTTMUSG00000035475 +629822 Ighv7-3 MGI:MGI:4439766|IMGT/GENE-DB:IGHV7-3 +629826 Ighv14-4 MGI:MGI:4439765|IMGT/GENE-DB:IGHV14-4 +629833 Ighv3-4 MGI:MGI:3644034|IMGT/GENE-DB:IGHV3-4 +629842 Ighv13-2 MGI:MGI:3705861|IMGT/GENE-DB:IGHV13-2 +629845 Ighv6-3 MGI:MGI:4439854|IMGT/GENE-DB:IGHV6-3 +629849 Ighv8-2 MGI:MGI:3647474|IMGT/GENE-DB:IGHV8-2 +629859 Ighv1-11 MGI:MGI:5009835|IMGT/GENE-DB:IGHV1-11 +629860 Ighv1-12 MGI:MGI:3646284|IMGT/GENE-DB:IGHV1-12 +629863 Ighv1-14 MGI:MGI:4439781|IMGT/GENE-DB:IGHV1-14 +629865 Ighv1-15 MGI:MGI:4439782|IMGT/GENE-DB:IGHV1-15 +629866 Ighv1-16 MGI:MGI:3647704|IMGT/GENE-DB:IGHV1-16 +629869 Ighv1-17 MGI:MGI:3647700|IMGT/GENE-DB:IGHV1-17 +629871 Ighv1-18 MGI:MGI:4439780|IMGT/GENE-DB:IGHV1-18 +629873 Krtap1-4 MGI:MGI:3651229|Ensembl:ENSMUSG00000075567|Vega:OTTMUSG00000004966 +629884 Ighv1-26 MGI:MGI:4439641|IMGT/GENE-DB:IGHV1-26 +629893 Ighv1-31 MGI:MGI:4439889|IMGT/GENE-DB:IGHV1-31 +629897 Ighv1-36 MGI:MGI:4439639|IMGT/GENE-DB:IGHV1-36 +629904 Ighv1-41 MGI:MGI:3649084|IMGT/GENE-DB:IGHV1-41 +629906 Ighv1-42 MGI:MGI:3704123|IMGT/GENE-DB:IGHV1-42 +629908 Ighv1-43 MGI:MGI:3704124|IMGT/GENE-DB:IGHV1-43 +629915 Ighv1-47 MGI:MGI:4439890|IMGT/GENE-DB:IGHV1-47 +629919 Ighv8-4 MGI:MGI:3646040|IMGT/GENE-DB:IGHV8-4 +629924 Gm11556 MGI:MGI:3651824 +629925 Ighv1-49 MGI:MGI:4439754|IMGT/GENE-DB:IGHV1-49 +629930 Ighv8-6 MGI:MGI:3645823|IMGT/GENE-DB:IGHV8-6 +629936 Gm7019 MGI:MGI:3645821 +629945 Cep112it MGI:MGI:3649867 +629949 Gm11619 MGI:MGI:3649910 +629957 Gm14303 MGI:MGI:3651379 +629959 Gm7020 MGI:MGI:3645610 +629960 Gm11639 MGI:MGI:3651790 +629967 Gm11677 MGI:MGI:3649553 +629970 Cd300ld2 MGI:MGI:3649405 +629971 Rpl36-ps1 MGI:MGI:3651798 +629997 Gm7022 MGI:MGI:3645203 +630022 Btbd35f18 MGI:MGI:3709282|Ensembl:ENSMUSG00000094876|Vega:OTTMUSG00000016405 +630028 Gm7023 MGI:MGI:3779647 +630061 Trav7-5 MGI:MGI:3648929|IMGT/GENE-DB:TRAV7-5 +630071 Gm7025 MGI:MGI:3645676 +630077 LOC630077 - +630086 Trav12-1 MGI:MGI:4440525|IMGT/GENE-DB:TRAV12-1 +630138 Gm7027 MGI:MGI:3644555 +630146 Cd101 MGI:MGI:2685862|Ensembl:ENSMUSG00000086564|Vega:OTTMUSG00000013107 +630169 Gm7028 MGI:MGI:3647943 +630195 Vhq52.a21.63 - +630219 Gm7029 MGI:MGI:3779650 +630270 Ighv4s2 - +630282 LOC630282 - +630294 Gm7030 MGI:MGI:3647514|Ensembl:ENSMUSG00000092243|Vega:OTTMUSG00000037034 +630298 Vh7183.a28.48 - +630331 LOC630331 - +630342 Vhvgam3.8.a4.102 - +630347 Ighvhs107.a3.106 - +630355 Gm7031 MGI:MGI:3646638 +630415 Trav14d-1 IMGT/GENE-DB:TRAV14D-1 +630424 Gm7033 MGI:MGI:3779651 +630453 Gm7034 MGI:MGI:3644650 +630461 Trav9-4 MGI:MGI:3702135|IMGT/GENE-DB:TRAV9-4 +630486 Ighv2-6 MGI:MGI:4439518|IMGT/GENE-DB:IGHV2-6 +630499 H2-K2 MGI:MGI:95906 +630537 Dcpp2 MGI:MGI:3644062|Ensembl:ENSMUSG00000096278 +630579 Zfp808 MGI:MGI:3704127|Ensembl:ENSMUSG00000074867|Vega:OTTMUSG00000033131 +630612 Gm17352 MGI:MGI:4936986 +630618 Gm7039 MGI:MGI:3779653 +630663 Gm7040 MGI:MGI:3779654 +630708 Gm7041 MGI:MGI:3646096 +630751 LOC630751 - +630757 Gm7042 MGI:MGI:3643634 +630810 Gm7043 MGI:MGI:3647242 +630836 2010315B03Rik MGI:MGI:1919321|Ensembl:ENSMUSG00000074829|Vega:OTTMUSG00000045945 +630845 Tas2r122 MGI:MGI:2681262|Ensembl:ENSMUSG00000078280|Vega:OTTMUSG00000057005 +630857 Gm7045 MGI:MGI:3779655 +630887 Gm12814 MGI:MGI:3651208 +630894 Gm7046 MGI:MGI:3779656 +630927 Gm7047 MGI:MGI:3643011 +630942 Gm7048 MGI:MGI:3779657 +630951 Gm7049 MGI:MGI:3646400 +630952 Ang6 MGI:MGI:3528602|Ensembl:ENSMUSG00000072598|Vega:OTTMUSG00000034644 +630994 Lce3d MGI:MGI:3642919|Ensembl:ENSMUSG00000043472|Vega:OTTMUSG00000044610 +631002 Ssxb8 MGI:MGI:2446777|Ensembl:ENSMUSG00000079703|Vega:OTTMUSG00000016840 +631010 Gm7052 MGI:MGI:3804969 +631037 Cyp4b1-ps2 MGI:MGI:3649236 +631071 Gm16589 MGI:MGI:4418561 +631097 Gm7054 MGI:MGI:3779659 +631101 Lce1k MGI:MGI:3702534|Ensembl:ENSMUSG00000095870|Vega:OTTMUSG00000051858 +631105 Gm7056 MGI:MGI:3779661 +631145 Fam90a1b MGI:MGI:1921682 +631243 Gm12101 MGI:MGI:3651193 +631264 Gm7058 MGI:MGI:3643915 +631266 Gm7059 MGI:MGI:3779663 +631304 Cyp4f40 MGI:MGI:3645508|Ensembl:ENSMUSG00000090700 +631319 Rpl13-ps5 MGI:MGI:3648527 +631323 Gm12250 MGI:MGI:3649299 +631331 Gm7061 MGI:MGI:3648315 +631359 Rpl21-ps14 MGI:MGI:3648110 +631371 Gm11784 MGI:MGI:3649457 +631379 Gm10292 MGI:MGI:3642851 +631400 Gm12950 MGI:MGI:3649504 +631406 Slfn13l - +631415 Gm20760 MGI:MGI:5434116 +631429 Gm7063 MGI:MGI:3644583 +631449 Gm7064 MGI:MGI:3644357 +631470 Gm7065 MGI:MGI:3647309 +631577 Gm7067 MGI:MGI:3779664 +631581 Gm16436 MGI:MGI:3645326 +631584 Catspere1 MGI:MGI:3647531 +631594 Gm7069 MGI:MGI:3645735 +631595 Ighv1-21-1 MGI:MGI:3645737|IMGT/GENE-DB:IGHV1-21-1 +631621 Gm7071 MGI:MGI:3779665 +631624 Gm7072 MGI:MGI:3648314 +631784 Gm7073 MGI:MGI:3779666|Ensembl:ENSMUSG00000079583|Vega:OTTMUSG00000046043 +631797 Fer1l6 MGI:MGI:3645398|Ensembl:ENSMUSG00000037106|Vega:OTTMUSG00000032988 +631868 Gm7074 MGI:MGI:3645420 +631906 Gm7075 MGI:MGI:3646561 +631922 Gm7076 MGI:MGI:3646842 +631990 Cdr1 MGI:MGI:88359|Ensembl:ENSMUSG00000090546 +632013 Gm7079 MGI:MGI:3643105 +632066 Zfp148-ps1 MGI:MGI:1332224 +632115 Gm7081 MGI:MGI:3779669 +632126 Btnl4 MGI:MGI:1932036|Ensembl:ENSMUSG00000058435|Vega:OTTMUSG00000020241 +632166 Gm7082 MGI:MGI:3647792 +632216 Gm15476 MGI:MGI:3643813 +632241 Gm29241 MGI:MGI:5579947 +632248 Gm7083 MGI:MGI:3647452 +632264 Gm14703 MGI:MGI:3705165 +632268 LOC632268 - +632287 Gm7084 MGI:MGI:3779670 +632302 Cyp21a2-ps MGI:MGI:3645529 +632352 Gm7085 MGI:MGI:3642962 +632394 Gm14251 MGI:MGI:3650992 +632412 Gm7086 MGI:MGI:3648861 +632454 Tpt1-ps6 MGI:MGI:2665000 +632482 Gm29689 MGI:MGI:5588848 +632498 Gm7089 MGI:MGI:3647982 +632534 Vmn1r191 MGI:MGI:2182258|Ensembl:ENSMUSG00000095916|Vega:OTTMUSG00000000477 +632649 Vmn2r-ps26 MGI:MGI:3761472 +632654 Ighv7-4 MGI:MGI:4439763|IMGT/GENE-DB:IGHV7-4 +632671 Vmn2r18 MGI:MGI:3645314|Ensembl:ENSMUSG00000091794|Vega:OTTMUSG00000055578 +632685 Gm7091 MGI:MGI:3643894 +632687 March10 MGI:MGI:2443469|Ensembl:ENSMUSG00000078627|Vega:OTTMUSG00000002988 +632708 Dmrtc1b MGI:MGI:3639121|Ensembl:ENSMUSG00000073027|Vega:OTTMUSG00000018163 +632737 Gm9890 MGI:MGI:3642649 +632745 LOC632745 - +632764 5730471H19Rik MGI:MGI:3642639 +632778 Erich4 MGI:MGI:3646269|Ensembl:ENSMUSG00000074261|Vega:OTTMUSG00000058392 +632781 Gm7093 MGI:MGI:3648655 +632784 Gm11621 MGI:MGI:3650006 +632793 Vmn1r204 MGI:MGI:3651399|Ensembl:ENSMUSG00000094637|Vega:OTTMUSG00000000494 +632802 Gm7094 MGI:MGI:3648114 +632883 Gm14989 MGI:MGI:3705366 +632886 LOC632886 - +632903 Gm7096 MGI:MGI:3646592 +632955 Gm7097 MGI:MGI:3779671 +632971 Rergl MGI:MGI:3642998|Ensembl:ENSMUSG00000092164|Vega:OTTMUSG00000057641 +632982 Cct3-ps1 MGI:MGI:109293 +633030 Gm7099 MGI:MGI:3646387 +633057 Gm7102 MGI:MGI:3648735|Ensembl:ENSMUSG00000094649|Vega:OTTMUSG00000042892 +633061 Gm13313 MGI:MGI:3651091 +633072 Gm7103 MGI:MGI:3646860 +633082 Gm12164 MGI:MGI:3650637 +633093 Gm7104 MGI:MGI:3779672 +633120 Gm7105 MGI:MGI:3644446 +633188 Gm20762 MGI:MGI:5434118 +633215 Gm7106 MGI:MGI:3649093 +633238 Gm7107 MGI:MGI:3648887 +633246 Gm7108 MGI:MGI:3645440 +633269 Gm12877 MGI:MGI:3650567 +633279 Gm12876 MGI:MGI:3651904 +633285 Rbm46 MGI:MGI:3645057|Ensembl:ENSMUSG00000033882|Vega:OTTMUSG00000043545 +633295 Tdpx-ps1 MGI:MGI:1321403 +633354 Gm14470 MGI:MGI:3650278 +633360 LOC633360 - +633361 Gm14480 MGI:MGI:3650191 +633395 Gm10548 MGI:MGI:3641893|Ensembl:ENSMUSG00000073607 +633457 Ighv3-5 MGI:MGI:3648045|IMGT/GENE-DB:IGHV3-5 +633484 Gm7113 MGI:MGI:3646064 +633498 Gm7114 MGI:MGI:3643085 +633522 Gm7115 MGI:MGI:3646388 +633568 Ighv5-16 MGI:MGI:4439556|IMGT/GENE-DB:IGHV5-16 +633570 Gm7117 MGI:MGI:3649027 +633596 Hmgn2l6 MGI:MGI:3708112 +633606 Gm7118 MGI:MGI:3648119 +633639 Gm7119 MGI:MGI:3644926 +633640 Tmem267 MGI:MGI:3648543|Ensembl:ENSMUSG00000074634|Vega:OTTMUSG00000042033 +633683 Rps15-ps2 MGI:MGI:3647234 +633692 Gm7122 MGI:MGI:3644290 +633695 Gm11855 MGI:MGI:3649313 +633710 LOC633710 - +633736 Gm7123 MGI:MGI:3646446 +633740 Trav5-1 MGI:MGI:3815062|IMGT/GENE-DB:TRAV5-1 +633752 Gm7125 MGI:MGI:3645829 +633774 LOC633774 - +633789 Gm7126 MGI:MGI:3648680 +633947 Gm6225 MGI:MGI:3643252|Ensembl:ENSMUSG00000097746 +633979 Ak9 MGI:MGI:2685080|Ensembl:ENSMUSG00000091415|Vega:OTTMUSG00000037166 +634008 Gm7128 MGI:MGI:3779675 +634019 Gm7129 MGI:MGI:3648820 +634104 Olfr287 MGI:MGI:3030121|Ensembl:ENSMUSG00000090129 +634132 Trav7-2 MGI:MGI:3649607|IMGT/GENE-DB:TRAV7-2 +634222 Gm5353 MGI:MGI:3643866 +634322 Trav14d-3-dv8 MGI:MGI:3822547|IMGT/GENE-DB:TRAV14D-3/DV8 +634323 Gm7132 MGI:MGI:3647002 +634331 Gm7133 MGI:MGI:3643070 +634340 Gm7134 MGI:MGI:3647708|Ensembl:ENSMUSG00000082853 +634346 Gm7135 MGI:MGI:3647710 +634386 Ftl1-ps1 MGI:MGI:3779109 +634504 Gm7137 MGI:MGI:3779677|Ensembl:ENSMUSG00000095721 +634517 Gm7138 MGI:MGI:3779678 +634588 Gm7140 MGI:MGI:3645817 +634594 LOC634594 - +634611 Gm10760 MGI:MGI:3642546 +634650 Gbp11 MGI:MGI:3646307|Ensembl:ENSMUSG00000092021|Vega:OTTMUSG00000042405 +634662 Gm7142 MGI:MGI:3646714 +634678 Gm7143 MGI:MGI:3646528 +634710 Gm11692 MGI:MGI:3652330 +634720 Gm11735 MGI:MGI:3713525 +634731 Susd1 MGI:MGI:3651543|Ensembl:ENSMUSG00000038578|Vega:OTTMUSG00000007332 +634762 Gm7145 MGI:MGI:3648947 +634825 Gm14851 MGI:MGI:3709605|Ensembl:ENSMUSG00000061958|Vega:OTTMUSG00000018260 +634834 Gm11821 MGI:MGI:3649777 +634869 LOC634869 - +634881 Gm7146 MGI:MGI:3645120 +634882 Itih5l-ps MGI:MGI:2685232 +634929 Scgb1b11 MGI:MGI:3779681 +634939 Gm13384 MGI:MGI:3650826 +634967 Tgif2-ps2 MGI:MGI:3805950 +635093 Gm15314 MGI:MGI:3705655 +635097 Gm11701 MGI:MGI:3650074 +635136 Gm7150 MGI:MGI:3643652 +635169 CK137956 MGI:MGI:3616080|Ensembl:ENSMUSG00000028813|Vega:OTTMUSG00000009374 +635187 Gm7151 MGI:MGI:3647523 +635209 Gm7152 MGI:MGI:3644255 +635243 Gm7153 MGI:MGI:3644674 +635253 Usp51 MGI:MGI:3588217|Ensembl:ENSMUSG00000067215|Vega:OTTMUSG00000019333 +635275 Oat-rs1 MGI:MGI:97395 +635295 Gm7155 MGI:MGI:3646473 +635344 Gm7156 MGI:MGI:3646023 +635396 Cldn34a MGI:MGI:3779684|Ensembl:ENSMUSG00000091863 +635412 Gm7158 MGI:MGI:3647927 +635455 Gm12026 MGI:MGI:3651190 +635470 Gm14407 MGI:MGI:3649809 +635497 Gm7159 MGI:MGI:3647037 +635504 Gm7160 MGI:MGI:3646078 +635513 LOC635513 - +635580 Gm16445 MGI:MGI:3649081 +635617 Gm7162 MGI:MGI:3645097 +635651 Gm20763 MGI:MGI:5434119 +635668 Fbxw23 MGI:MGI:3779686 +635702 Naaladl2 MGI:MGI:2685867|Ensembl:ENSMUSG00000102758|Vega:OTTMUSG00000051138 +635719 Gm7164 MGI:MGI:3646195 +635756 Gm7166 MGI:MGI:3779688 +635803 Gm12757 MGI:MGI:3649706 +635871 Gm7167 MGI:MGI:3647878 +635895 Gm7168 MGI:MGI:3643198|Ensembl:ENSMUSG00000067941|Vega:OTTMUSG00000045332 +635960 Ak3l2-ps MGI:MGI:3574349 +636009 Gm14942 MGI:MGI:3646389 +636017 LOC636017 - +636070 Gm7172 MGI:MGI:3643000 +636082 Gm16462 MGI:MGI:3642993 +636104 Gm7173 MGI:MGI:3645063|Ensembl:ENSMUSG00000073077 +636127 Trav7n-4 MGI:MGI:3644878|IMGT/GENE-DB:TRAV7N-4 +636173 Vmn2r-ps23 MGI:MGI:3761467 +636177 Rhox4f MGI:MGI:3613392|Ensembl:ENSMUSG00000079630|Vega:OTTMUSG00000017153 +636187 Gm20764 MGI:MGI:5434120 +636260 Ighv9-4 MGI:MGI:3646379|IMGT/GENE-DB:IGHV9-4 +636450 Gm15596 MGI:MGI:3783043 +636462 Ighv8-11 MGI:MGI:3644925|IMGT/GENE-DB:IGHV8-11 +636474 Gm17752 MGI:MGI:5009836 +636532 Gm12125 MGI:MGI:3652212 +636544 Gm7180 MGI:MGI:3648560 +636612 Gm7181 MGI:MGI:3644423 +636659 Gm7182 MGI:MGI:3644877 +636680 Gm7183 MGI:MGI:3779691 +636697 Vmn1r60 MGI:MGI:3645244|Ensembl:ENSMUSG00000090794|Vega:OTTMUSG00000037743 +636731 Vmn1r61 MGI:MGI:3779692|Ensembl:ENSMUSG00000094313|Vega:OTTMUSG00000037746 +636735 Gm14570 MGI:MGI:3643340 +636741 Zfp964 MGI:MGI:3646490|Ensembl:ENSMUSG00000091764|Vega:OTTMUSG00000056642 +636752 Igkv4-62 MGI:MGI:3643587|IMGT/GENE-DB:IGKV4-62 +636756 Gm7189 MGI:MGI:3643586 +636766 Gm7190 MGI:MGI:3646744 +636791 Gm9866 MGI:MGI:3643118|Ensembl:ENSMUSG00000094002 +636808 Cntnap5a MGI:MGI:3643623|Ensembl:ENSMUSG00000070695|Vega:OTTMUSG00000022099 +636847 Gm12912 MGI:MGI:3649320 +636859 Gm7191 MGI:MGI:3779693 +636910 Zfp813-ps MGI:MGI:3645355 +636915 Gm7192 MGI:MGI:3704115 +636931 Trim71 MGI:MGI:2685973|Ensembl:ENSMUSG00000079259|Vega:OTTMUSG00000044351 +636952 Gm7194 MGI:MGI:3645774 +636972 Gm7195 MGI:MGI:3779695 +637004 Vmn2r3 MGI:MGI:3643995|Ensembl:ENSMUSG00000091572|Vega:OTTMUSG00000039827 +637008 Gm11793 MGI:MGI:3652124 +637021 Vmn2r124 MGI:MGI:3761531|Ensembl:ENSMUSG00000094396|Vega:OTTMUSG00000039014 +637027 Mageb7-ps MGI:MGI:2148171 +637043 Gm7198 MGI:MGI:3779696 +637050 Ighv1-10 MGI:MGI:5009837|IMGT/GENE-DB:IGHV1-10 +637051 Gm7199 MGI:MGI:3645878 +637053 Vmn2r4 MGI:MGI:3648229|Ensembl:ENSMUSG00000092049|Vega:OTTMUSG00000039830 +637079 Gm16486 MGI:MGI:3708784|Ensembl:ENSMUSG00000110622|Vega:OTTMUSG00000061542 +637083 Gm7200 MGI:MGI:3644666 +637093 Tex13c1 MGI:MGI:2685208|Ensembl:ENSMUSG00000078320|Vega:OTTMUSG00000017328 +637141 Gm14603 MGI:MGI:3705623 +637157 Gm7201 MGI:MGI:3647123 +637227 Igkv6-23 MGI:MGI:3711980|IMGT/GENE-DB:IGKV6-23 +637235 Gm13337 MGI:MGI:3650269 +637237 Gm7203 MGI:MGI:3645479 +637260 LOC637260 - +637273 Gm7204 MGI:MGI:3645884 +637277 Sycp2l MGI:MGI:2685114 +637307 Gm7205 MGI:MGI:3643966 +637379 Gm7206 MGI:MGI:3646634 +637515 Nlrp1b MGI:MGI:3582959|Ensembl:ENSMUSG00000070390|Vega:OTTMUSG00000006087 +637541 Gm7207 MGI:MGI:3644835 +637550 Gm7208 MGI:MGI:3648500 +637566 Gm7209 MGI:MGI:3645245 +637571 Gm7210 MGI:MGI:3648272 +637572 Gm7211 MGI:MGI:3648273 +637576 Gm7212 MGI:MGI:3648271 +637578 Gm20765 MGI:MGI:5434121|Ensembl:ENSMUSG00000095022|Vega:OTTMUSG00000042983 +637620 Gm7213 MGI:MGI:3646164 +637627 Gm7214 MGI:MGI:3779697 +637652 Vmn2r-ps81 MGI:MGI:3761326 +637667 Vmn2r-ps82 MGI:MGI:3761327 +637720 Gm7217 MGI:MGI:3648146 +637748 Rpl21-ps8 MGI:MGI:3648345 +637749 Gm10543 MGI:MGI:3648344 +637758 Gm7219 MGI:MGI:3645144 +637776 Zfp977 MGI:MGI:3645327 +637800 Gm7222 MGI:MGI:3642944 +637873 Vmn2r61 MGI:MGI:1351347|Ensembl:ENSMUSG00000090967|Vega:OTTMUSG00000037946 +637881 Vmn2r-ps87 MGI:MGI:3761334 +637896 Vmn2r78 MGI:MGI:3761335|Ensembl:ENSMUSG00000091962|Vega:OTTMUSG00000037781 +637898 Vmn2r60 MGI:MGI:3647050|Ensembl:ENSMUSG00000090619|Vega:OTTMUSG00000037944 +637900 Gm12618 MGI:MGI:3649881|Ensembl:ENSMUSG00000083016 +637908 Vmn2r53 MGI:MGI:3644480|Ensembl:ENSMUSG00000096002|Vega:OTTMUSG00000038268 +637913 Gm7224 MGI:MGI:3647435 +637939 Mark1-ps2 MGI:MGI:5645794 +637957 Gm7226 MGI:MGI:3779699 +638021 Gm13836 MGI:MGI:3650922 +638056 Vmn2r-ps133 MGI:MGI:3761693 +638068 Gm7229 MGI:MGI:3648920 +638102 Vmn2r115 MGI:MGI:3647235|Ensembl:ENSMUSG00000091076|Vega:OTTMUSG00000039965 +638170 Gm7230 MGI:MGI:3779700 +638247 9530082P21Rik MGI:MGI:3603340|Ensembl:ENSMUSG00000097006 +638251 Sult2a7 MGI:MGI:3645246|Ensembl:ENSMUSG00000094156|Vega:OTTMUSG00000048133 +638252 Gm7232 MGI:MGI:3645247 +638262 Gm7233 MGI:MGI:3648176|Ensembl:ENSMUSG00000094151|Vega:OTTMUSG00000036368 +638338 Obox4-ps35 MGI:MGI:3646889 +638345 Sbpl MGI:MGI:3694550|Ensembl:ENSMUSG00000024125 +638353 Gm7236 MGI:MGI:3646628 +638381 Gm7237 MGI:MGI:3779701 +638411 Gm10109 MGI:MGI:3647742|Ensembl:ENSMUSG00000062073 +638453 Gm7238 MGI:MGI:3647237 +638487 Gm7239 MGI:MGI:3645538 +638502 Gm7240 MGI:MGI:3643235 +638532 Gm7241 MGI:MGI:3646637 +638533 Gm7242 MGI:MGI:3646636 +638566 Trav13-2 MGI:MGI:3651611|IMGT/GENE-DB:TRAV13-2 +638575 Gm9779 MGI:MGI:3642092 +638580 Gm7244 MGI:MGI:3644192 +638605 Ighv2-5 MGI:MGI:4439517|IMGT/GENE-DB:IGHV2-5 +638631 Vhq52.a23.68 - +638634 Ighv1-70 MGI:MGI:3644620|IMGT/GENE-DB:IGHV1-70 +638695 Gm7247 MGI:MGI:3643454 +638698 Gm7248 MGI:MGI:3643458 +638720 Gm11990 MGI:MGI:3651122 +638833 Gm7251 MGI:MGI:3646144 +638858 Gm7252 MGI:MGI:3643964 +638867 Gm7253 MGI:MGI:3779705 +638890 Gm12690 MGI:MGI:3650444 +638903 Gm11516 MGI:MGI:3649759 +638904 Mgam2-ps MGI:MGI:3645497 +638950 Gm7255 MGI:MGI:3779706 +638988 Cyp2c53-ps MGI:MGI:3646306|Ensembl:ENSMUSG00000093610 +638991 Gm13047 MGI:MGI:3651114 +638995 Gm7256 MGI:MGI:3643372 +639025 Gm7257 MGI:MGI:3647831|Ensembl:ENSMUSG00000023093|Vega:OTTMUSG00000044739 +639030 Gm7258 MGI:MGI:3644893 +639044 Gm7259 MGI:MGI:3648502 +639105 Gm7260 MGI:MGI:3779707 +639116 Mrgprb11-ps MGI:MGI:3033189 +639162 Rps15a-ps1 MGI:MGI:3643034 +639207 Cyp2c73-ps MGI:MGI:3721927 +639281 Gm10382 MGI:MGI:3647829 +639390 BC094435 MGI:MGI:3642080 +639396 Gm7265 MGI:MGI:3648991 +639456 Gm7266 MGI:MGI:3648608 +639491 Gm13543 MGI:MGI:3649448 +639510 Ighv6-5 MGI:MGI:3647134|IMGT/GENE-DB:IGHV6-5 +639527 Gm7269 MGI:MGI:3647515 +639530 Gm7270 MGI:MGI:3644317 +639545 Gm7271 MGI:MGI:3647743|Ensembl:ENSMUSG00000091204|Vega:OTTMUSG00000047186 +639558 Gm7272 MGI:MGI:3644553 +639576 Gm7273 MGI:MGI:3644751 +639606 Gm10420 MGI:MGI:3704275 +639618 Gm7274 MGI:MGI:3646110 +639634 Aadacl2 MGI:MGI:3646333|Ensembl:ENSMUSG00000091376|Vega:OTTMUSG00000052012 +639644 Gm7275 MGI:MGI:3643404 +639653 Gm7276 MGI:MGI:3646549 +639655 Trav13d-4 MGI:MGI:4440515|IMGT/GENE-DB:TRAV13D-4 +639658 Gm13807 MGI:MGI:3650023|Ensembl:ENSMUSG00000085852 +639769 Adh6-ps1 MGI:MGI:1918999|Ensembl:ENSMUSG00000090306 +639774 Skint8 MGI:MGI:3651523|Ensembl:ENSMUSG00000078599 +639781 Skint1 MGI:MGI:3649627|Ensembl:ENSMUSG00000089773|Vega:OTTMUSG00000008542 +639787 Gm7278 MGI:MGI:3645261 +639802 Prb3-ps MGI:MGI:3644500 +639820 Gm7280 MGI:MGI:3643369 +639868 Gm7281 MGI:MGI:3779713 +639910 Gm20767 MGI:MGI:5434123|Ensembl:ENSMUSG00000096323 +639946 Klra27 MGI:MGI:2653802 +639964 Gm7283 MGI:MGI:3779714 +640017 Gm20768 MGI:MGI:5434124 +640020 Muc3b - +640046 Ighv2-9 MGI:MGI:4439624|IMGT/GENE-DB:IGHV2-9 +640050 Gm7285 MGI:MGI:3647212 +640094 Gm7286 MGI:MGI:3645875 +640145 Gm7287 MGI:MGI:3779715 +640171 Ctsm-ps MGI:MGI:2656172 +640196 Trav11d MGI:MGI:3649423|IMGT/GENE-DB:TRAV11D +640234 Gm7289 MGI:MGI:3644187 +640264 Gm7290 MGI:MGI:3646633 +640268 Nxpe1-ps MGI:MGI:3646632 +640324 Gm7291 MGI:MGI:3779716 +640340 Igkv8-16 MGI:MGI:1330843|IMGT/GENE-DB:IGKV8-16 +640370 Gm7292 MGI:MGI:3645786 +640374 Gm7293 MGI:MGI:3779717 +640461 Gm14016 MGI:MGI:3650953 +640489 Gm7295 MGI:MGI:3645098 +640497 Ighv1-25 MGI:MGI:3648295|IMGT/GENE-DB:IGHV1-25 +640506 Ighv8-5 MGI:MGI:3645478|IMGT/GENE-DB:IGHV8-5 +640524 Sptbn5 MGI:MGI:2685200 +640530 Gm7298 MGI:MGI:3648717 +640532 Gm7299 MGI:MGI:3648716 +640543 Tgm7 MGI:MGI:2151164|Ensembl:ENSMUSG00000079103|Vega:OTTMUSG00000015968 +640577 Itln6 MGI:MGI:4943971 +640627 Gm9789 MGI:MGI:3642043|Ensembl:ENSMUSG00000044227|Vega:OTTMUSG00000046404 +640694 Gm7307 MGI:MGI:3645397 +640703 Gm7308 MGI:MGI:3644558 +640755 Gm7309 MGI:MGI:3779723 +640803 Gm7312 MGI:MGI:3646347 +640892 Gm7313 MGI:MGI:3779725 +640914 Gm14107 MGI:MGI:3651301 +640931 Trav13d-1 MGI:MGI:3652171|IMGT/GENE-DB:TRAV13D-1 +640970 LOC640970 - +640992 Gm7316 MGI:MGI:3645493 +641025 LOC641025 - +641088 LOC641088 - +641104 Gm7318 MGI:MGI:3648501 +641121 Gm7319 MGI:MGI:3648719 +641130 Gm20769 MGI:MGI:5434125 +641178 Ighv5-9-1 MGI:MGI:4439810|IMGT/GENE-DB:IGHV5-9-1 +641247 Ighv1-33 MGI:MGI:4439617|IMGT/GENE-DB:IGHV1-33 +641254 Gm13351 MGI:MGI:3651067 +641340 Nrbf2 MGI:MGI:1354950|Ensembl:ENSMUSG00000075000|Vega:OTTMUSG00000028050 +641361 Pinlyp MGI:MGI:3615324|Ensembl:ENSMUSG00000011632|Vega:OTTMUSG00000058220 +641366 F630007L15Rik MGI:MGI:3644552 +641368 Spint5 MGI:MGI:3651687|Ensembl:ENSMUSG00000074593|Vega:OTTMUSG00000016293 +641376 Tomm40l MGI:MGI:3589112|Ensembl:ENSMUSG00000005674|Vega:OTTMUSG00000021586 +641385 2810430I11Rik MGI:MGI:3590515 +641387 1700120B22Rik MGI:MGI:3604190 +641453 F730048M01Rik MGI:MGI:3604191 +641454 5830444B04Rik MGI:MGI:3603170|Ensembl:ENSMUSG00000084803 +641660 Rpl7a-ps11 MGI:MGI:3644020 +652920 Gm12870 MGI:MGI:3649408 +652925 Tmem243 MGI:MGI:3606159|Ensembl:ENSMUSG00000079659|Vega:OTTMUSG00000054370 +652986 Rpl18-ps2 MGI:MGI:3646997 +652987 Gm12582 MGI:MGI:3651489 +652988 Gm7324 MGI:MGI:3646999 +652989 Rpl32p - +653016 Mymx MGI:MGI:3649059|Ensembl:ENSMUSG00000079471|Vega:OTTMUSG00000059717 +653029 Arhgap27os2 MGI:MGI:3650160 +653030 Arhgap27os3 MGI:MGI:3650159|Ensembl:ENSMUSG00000085887 +653909 C230098j07rik - +654309 Nrp Ensembl:ENSMUSG00000079036 +654318 C530005A16Rik MGI:MGI:3612454|Ensembl:ENSMUSG00000085408 +654352 Gm7326 MGI:MGI:3643460 +654353 Gm7327 MGI:MGI:3646274 +654354 Gm13443 MGI:MGI:3649615 +654355 Gm7328 MGI:MGI:3644705 +654356 Gm7329 MGI:MGI:3646271 +654358 Gm7331 MGI:MGI:3644702 +654359 Gm12338 MGI:MGI:3650622 +654360 Gm13360 MGI:MGI:3652147 +654361 Gm7332 MGI:MGI:3643344 +654362 Fbxw7as1 MGI:MGI:3614654 +654409 4932416H05Rik MGI:MGI:3606162 +654424 Mccc1os MGI:MGI:3590669|Ensembl:ENSMUSG00000086392 +654426 LOC654426 - +654431 Gm7333 MGI:MGI:3647839 +654432 Gm7334 MGI:MGI:3647393|Ensembl:ENSMUSG00000044645 +654435 C79927 MGI:MGI:3029728 +654436 C79947 MGI:MGI:3029729 +654437 C79589 MGI:MGI:3029906 +654438 A630031M23Rik MGI:MGI:3609648 +654439 D430004P15Rik MGI:MGI:3609650 +654440 A430046D13Rik MGI:MGI:3609643|Ensembl:ENSMUSG00000097353 +654445 Gm12098 MGI:MGI:3651581 +654449 Klra14-ps MGI:MGI:1321089|Ensembl:ENSMUSG00000072721 +654452 Defa-ps12 MGI:MGI:3647175 +654453 Defb33 MGI:MGI:3647176|Ensembl:ENSMUSG00000074454|Vega:OTTMUSG00000018925 +654454 Defb44-ps MGI:MGI:3646526|Ensembl:ENSMUSG00000070977 +654455 Gm21944 MGI:MGI:5439395 +654456 Defa-ps13 MGI:MGI:3705864|Ensembl:ENSMUSG00000081154 +654457 Defb26 MGI:MGI:3643488|Ensembl:ENSMUSG00000074680|Vega:OTTMUSG00000029050 +654458 Defb43 MGI:MGI:3647180|Ensembl:ENSMUSG00000075572|Vega:OTTMUSG00000020962 +654459 Defb25 MGI:MGI:3651158|Ensembl:ENSMUSG00000074678|Vega:OTTMUSG00000015862 +654460 Defb18 MGI:MGI:3648148|Ensembl:ENSMUSG00000073735|Vega:OTTMUSG00000020949 +654462 Kncn MGI:MGI:3614952|Ensembl:ENSMUSG00000073774|Vega:OTTMUSG00000008710 +654465 Defb47 MGI:MGI:3644478|Ensembl:ENSMUSG00000075573|Vega:OTTMUSG00000020963 +654467 Gm10052 MGI:MGI:3704348 +654468 Gm7335 MGI:MGI:3644473 +654469 Gm17753 MGI:MGI:5009838 +654470 Tctn1 MGI:MGI:3603820|Ensembl:ENSMUSG00000038593|Vega:OTTMUSG00000022563 +654472 Gm12070 MGI:MGI:3650751 +654473 Gm7336 MGI:MGI:3644851 +654474 Gm14760 MGI:MGI:3709612 +654475 Gm12671 MGI:MGI:3651684 +654493 8030494B02Rik MGI:MGI:3611235 +654494 Gm7337 MGI:MGI:3646689|Ensembl:ENSMUSG00000067156 +654498 Hhla1 MGI:MGI:3615329|Ensembl:ENSMUSG00000072511|Vega:OTTMUSG00000037580 +654788 4732440D04Rik MGI:MGI:3604103 +654793 G630016G05Rik MGI:MGI:3603178 +654795 Sdr39u1 MGI:MGI:1916876|Ensembl:ENSMUSG00000022223 +654796 9530036O11Rik MGI:MGI:2444607|Ensembl:ENSMUSG00000097726 +654798 D030055H07Rik MGI:MGI:3605036 +654799 4930594M22Rik MGI:MGI:1925478 +654800 A730085K08Rik MGI:MGI:3605633 +654801 Zfp784 MGI:MGI:3606042|Ensembl:ENSMUSG00000043290|Vega:OTTMUSG00000029125 +654802 1700105P06Rik MGI:MGI:1915479 +654803 B130055M24Rik MGI:MGI:3590645 +654804 4732471J01Rik MGI:MGI:3603586|Ensembl:ENSMUSG00000053714 +654805 F930015N05Rik MGI:MGI:3606161 +654806 A930029G22Rik MGI:MGI:3605039 +654807 A230005M16Rik MGI:MGI:3603401 +654809 4930428O21Rik MGI:MGI:1923034|Ensembl:ENSMUSG00000106333 +654810 Appbp2os MGI:MGI:3603817|Ensembl:ENSMUSG00000085628 +654811 4930404A12Rik MGI:MGI:3605803 +654812 Angptl7 MGI:MGI:3605801|Ensembl:ENSMUSG00000028989|Vega:OTTMUSG00000010933 +654818 Smco3 MGI:MGI:2443451|Ensembl:ENSMUSG00000043298|Vega:OTTMUSG00000024468 +654819 9930004E17Rik MGI:MGI:3603579 +654820 G530011O06Rik MGI:MGI:3603513|Ensembl:ENSMUSG00000072844 +654821 Gcnt7 MGI:MGI:3606143|Ensembl:ENSMUSG00000074569|Vega:OTTMUSG00000016159 +654822 D330041H03Rik MGI:MGI:3603827|Ensembl:ENSMUSG00000073437 +654823 B930094E09Rik MGI:MGI:3603750 +654824 Ankrd37 MGI:MGI:3603344|Ensembl:ENSMUSG00000050914|Vega:OTTMUSG00000022873 +654836 Trav12-3 MGI:MGI:3648633|IMGT/GENE-DB:TRAV12-3 +654838 Traj2 MGI:MGI:4840255|IMGT/GENE-DB:TRAJ2 +654839 Traj5 MGI:MGI:4840258|IMGT/GENE-DB:TRAJ5 +664608 Rhox4g MGI:MGI:3613394|Ensembl:ENSMUSG00000079628|Vega:OTTMUSG00000017151 +664609 Rhox4a MGI:MGI:3580240|Ensembl:ENSMUSG00000079639|Vega:OTTMUSG00000017121 +664610 Rhox4d MGI:MGI:3613388|Ensembl:ENSMUSG00000079633|Vega:OTTMUSG00000017146 +664619 4921533I20Rik MGI:MGI:3613759 +664620 4933427I04Rik MGI:MGI:3613760 +664628 LOC664628 - +664702 A530088E08Rik MGI:MGI:3603459 +664703 Cypt13 MGI:MGI:3616457 +664705 Cypt11 MGI:MGI:3616454 +664723 Cypt8 MGI:MGI:3616448 +664724 Cypt9 MGI:MGI:3616450 +664725 Cypt7 MGI:MGI:3616446 +664726 Cypt10 MGI:MGI:3616452 +664778 Gm10350 MGI:MGI:3642728 +664779 Gm44505 MGI:MGI:3845910|Ensembl:ENSMUSG00000024695|Vega:OTTMUSG00000034852 +664781 Gm7338 MGI:MGI:3779731 +664783 Dux MGI:MGI:3703875 +664785 Gm12608 MGI:MGI:3652144 +664787 LOC664787 Ensembl:ENSMUSG00000079222 +664791 Gm7340 MGI:MGI:3648496 +664792 Gm7341 MGI:MGI:3648497 +664793 Zp4-ps MGI:MGI:3690088|Ensembl:ENSMUSG00000113593 +664795 Gm7343 MGI:MGI:3648493 +664797 Gm7344 MGI:MGI:3648494 +664799 Ctcfl MGI:MGI:3652571|Ensembl:ENSMUSG00000070495|Vega:OTTMUSG00000016680 +664801 Gm7346 MGI:MGI:3645982 +664804 Gm7347 MGI:MGI:3645983|Ensembl:ENSMUSG00000073117|Vega:OTTMUSG00000036611 +664805 Skor2 MGI:MGI:3645984|Ensembl:ENSMUSG00000091519 +664810 Gm7350 MGI:MGI:3779733 +664812 Gm7351 MGI:MGI:3643013 +664814 Gm7352 MGI:MGI:3643017 +664817 Gm7353 MGI:MGI:3643014 +664821 Gm7356 MGI:MGI:3646178 +664822 Gm13331 MGI:MGI:3649454 +664829 Slx MGI:MGI:99543|Ensembl:ENSMUSG00000095063|Vega:OTTMUSG00000017010 +664830 Gm7357 MGI:MGI:3643257 +664831 Gm7358 MGI:MGI:3643256 +664835 Gm13422 MGI:MGI:3650167 +664837 Gm7361 MGI:MGI:3805965|Ensembl:ENSMUSG00000059645|Vega:OTTMUSG00000036615 +664840 Gm12643 MGI:MGI:3649676 +664841 Gm7363 MGI:MGI:3646407 +664843 Gm7364 MGI:MGI:3646409 +664844 Gm7365 MGI:MGI:3779735 +664846 Gm7366 MGI:MGI:3646406 +664848 Gm12644 MGI:MGI:3649677 +664849 Gm7367 MGI:MGI:3646404 +664850 Gm7368 MGI:MGI:3643487 +664851 Gm15538 MGI:MGI:3782986 +664853 Gm7369 MGI:MGI:3643485 +664854 Gm7370 MGI:MGI:3779736 +664858 Gm45231 MGI:MGI:5753807 +664861 Gm7375 MGI:MGI:3646621 +664862 Gpr137b-ps MGI:MGI:3710533 +664867 Gm7378 MGI:MGI:3646622 +664868 Rpl38-ps2 MGI:MGI:3646625 +664869 Gm7380 MGI:MGI:3646626 +664870 Gm7381 MGI:MGI:3643743 +664872 Gm7382 MGI:MGI:3643745 +664875 Gm7384 MGI:MGI:3643739 +664876 Gm7385 MGI:MGI:3643742 +664877 Gm7386 MGI:MGI:3643741 +664880 Gm14336 MGI:MGI:3649933 +664883 Nova1 MGI:MGI:104297|Ensembl:ENSMUSG00000021047 +664888 Gm7389 MGI:MGI:3645153 +664889 Gm7390 MGI:MGI:3645154 +664890 Gm7391 MGI:MGI:3648359|Ensembl:ENSMUSG00000095494 +664891 Gm7392 MGI:MGI:3648358 +664893 Gm7393 MGI:MGI:3648357 +664894 Gm13215 MGI:MGI:3650813|Ensembl:ENSMUSG00000081394 +664895 Ywhaq-ps2 MGI:MGI:3650308 +664896 Gm7394 MGI:MGI:3648361 +664897 Gm7395 MGI:MGI:3648360 +664900 Gm16518 MGI:MGI:4360828 +664901 Vamp7-ps MGI:MGI:3652239 +664903 Rps15a-ps4 MGI:MGI:3652187 +664905 Gm7397 MGI:MGI:3647493 +664906 Gm7398 MGI:MGI:3647496 +664907 Gm7399 MGI:MGI:3647495 +664909 Gm7400 MGI:MGI:3647488 +664911 Gm11878 MGI:MGI:3651784 +664918 Gm7405 MGI:MGI:3644301 +664919 Gm7406 MGI:MGI:3644302 +664920 Gm11952 MGI:MGI:3650309 +664922 Gm7407 MGI:MGI:3647246 +664923 Gm7408 MGI:MGI:3647245 +664924 Gm20770 MGI:MGI:5434126 +664931 Gm7411 MGI:MGI:3644066 +664935 Gm7412 MGI:MGI:3644068 +664936 Gm7413 MGI:MGI:3644069 +664938 Gm13416 MGI:MGI:3652158 +664942 Gm13858 MGI:MGI:3649681 +664944 Gm7415 MGI:MGI:3647748 +664945 Gm7416 MGI:MGI:3647901 +664946 Gm7417 MGI:MGI:3647903 +664947 Gm7418 MGI:MGI:3779742 +664948 Gm7419 MGI:MGI:3779743 +664949 Gm7420 MGI:MGI:3647909 +664951 Gm7421 MGI:MGI:3779744 +664952 Gm7422 MGI:MGI:3644726 +664953 Gm7423 MGI:MGI:3644727 +664956 Gm7424 MGI:MGI:3644728 +664957 Gm7425 MGI:MGI:3644729 +664958 Gm14527 MGI:MGI:3802087 +664960 Gm7426 MGI:MGI:3647725 +664965 Gm7428 MGI:MGI:3647720 +664967 Vmn1r-ps1 MGI:MGI:3650321 +664968 Tmem238 MGI:MGI:1922935|Ensembl:ENSMUSG00000030431|Vega:OTTMUSG00000058436 +664969 Gm7429 MGI:MGI:3647718 +664972 Gm7430 MGI:MGI:3644532 +664973 Gm11892 MGI:MGI:3651298 +664975 Gm7432 MGI:MGI:3645713 +664977 Gm7434 MGI:MGI:3644530 +664980 Gm7435 MGI:MGI:3646489 +664981 Gm7436 MGI:MGI:3646488 +664982 Gm7437 MGI:MGI:3779747 +664987 Gm14393 MGI:MGI:3649576|Ensembl:ENSMUSG00000078905|Vega:OTTMUSG00000016546 +664989 Gm7438 MGI:MGI:3646492 +664991 Gm12917 MGI:MGI:3652006 +664994 Isoc2a MGI:MGI:3609243|Ensembl:ENSMUSG00000086784|Vega:OTTMUSG00000058579 +664995 Gm7439 MGI:MGI:3643341 +665000 Gm7441 MGI:MGI:3644941 +665001 Gm14391 MGI:MGI:3709324|Ensembl:ENSMUSG00000078903|Ensembl:ENSMUSG00000090093|Vega:OTTMUSG00000016543|Vega:OTTMUSG00000016567 +665002 Gm7442 MGI:MGI:3644940 +665004 Gm7443 MGI:MGI:3644945 +665005 Gm7444 MGI:MGI:3644944 +665007 Gm7445 MGI:MGI:3644942 +665008 Gm7446 MGI:MGI:3644947 +665009 Gm7447 MGI:MGI:3644946 +665015 Gm7449 MGI:MGI:3647895 +665017 Gm7450 MGI:MGI:3647897 +665019 Gm11897 MGI:MGI:3651206 +665020 LOC665020 - +665021 Gm7451 MGI:MGI:3645148 +665024 Gm7452 MGI:MGI:3645151 +665029 Gm12704 MGI:MGI:3650671 +665032 Gm13841 MGI:MGI:3650890 +665033 Col6a5 MGI:MGI:3648134|Ensembl:ENSMUSG00000091345|Vega:OTTMUSG00000049419 +665035 Gm15560 MGI:MGI:3783009 +665036 Gm7456 MGI:MGI:3648131 +665037 Gm7457 MGI:MGI:3648132|Ensembl:ENSMUSG00000072683 +665038 Vmn2r-ps61 MGI:MGI:3757996 +665041 Gm7459 MGI:MGI:3645341 +665044 Gm7461 MGI:MGI:3645338 +665046 Gm7463 MGI:MGI:3645336 +665047 Gm7464 MGI:MGI:3645335 +665053 Gm7466 MGI:MGI:3648356 +665054 D330025C20Rik MGI:MGI:3588219 +665055 Gm7467 MGI:MGI:3648350|Ensembl:ENSMUSG00000098449 +665056 Gm7468 MGI:MGI:3648351 +665057 Cbx3-ps8 MGI:MGI:3648352 +665063 Gm7470 MGI:MGI:3645544 +665066 Gm14911 MGI:MGI:3705521 +665068 Gm7473 MGI:MGI:3645547 +665069 Rps2-ps2 MGI:MGI:3645546 +665071 Gm7476 MGI:MGI:3648574 +665072 Gm7477 MGI:MGI:3648571 +665073 Gm7478 MGI:MGI:3648572 +665075 Gm7480 MGI:MGI:3648577 +665077 Gm7481 MGI:MGI:3648575 +665079 Gm11903 MGI:MGI:3651055 +665083 Gm7482 MGI:MGI:3645480 +665085 Gm7483 MGI:MGI:3644061 +665087 Gm7485 MGI:MGI:3644059 +665089 Spr-ps1 MGI:MGI:1345187 +665094 Gm7488 MGI:MGI:3647006 +665095 Cyp2j8 MGI:MGI:2449817|Ensembl:ENSMUSG00000082932|Vega:OTTMUSG00000007938 +665097 Gm7489 MGI:MGI:3647008 +665102 Gm7492 MGI:MGI:3648381 +665103 Gm7493 MGI:MGI:3643471 +665107 Gm7494 MGI:MGI:3643474 +665108 Gm7495 MGI:MGI:3643468 +665110 Gm15568 MGI:MGI:3783017 +665111 Gm7497 MGI:MGI:3646548 +665113 Tnik MGI:MGI:1916264|Ensembl:ENSMUSG00000027692|Vega:OTTMUSG00000030434 +665114 Gm7498 MGI:MGI:3646544 +665116 Gm7499 MGI:MGI:3646612 +665117 Gm7500 MGI:MGI:3646611 +665119 Sec14l5 MGI:MGI:3616084|Ensembl:ENSMUSG00000091712 +665120 Gm7501 MGI:MGI:3643244 +665121 Gm7502 MGI:MGI:3643245 +665124 Gm7503 MGI:MGI:3643240 +665125 Gm7504 MGI:MGI:3643241 +665127 Gm7506 MGI:MGI:3643243 +665129 Gm7507 MGI:MGI:3643248 +665130 Gm7508 MGI:MGI:3646398 +665137 Gm7511 MGI:MGI:3646392 +665138 Gm7512 MGI:MGI:3646401 +665140 Gm7513 MGI:MGI:3643010 +665141 Gm11908 MGI:MGI:3650143 +665143 Gm7514 MGI:MGI:3643009 +665144 Gm7515 MGI:MGI:3643006 +665145 Gm7516 MGI:MGI:3643007 +665146 Gm7517 MGI:MGI:3643004 +665149 Sox5os5 MGI:MGI:3643003 +665150 Vmn1r57 MGI:MGI:3646165|Ensembl:ENSMUSG00000091652|Vega:OTTMUSG00000037747 +665155 Srp54b MGI:MGI:3714357|Ensembl:ENSMUSG00000112449 +665161 Gm7523 MGI:MGI:3649032 +665162 Gm15754 MGI:MGI:3783197 +665172 Gm7525 MGI:MGI:3645975 +665174 Gm11543 MGI:MGI:3705877 +665176 Gm7527 MGI:MGI:3645979 +665178 Gm7529 MGI:MGI:3645973 +665180 Clec2l MGI:MGI:2141402|Ensembl:ENSMUSG00000079598 +665181 Gm11964 MGI:MGI:3652241 +665182 Gm7530 MGI:MGI:3644432 +665183 Gm7531 MGI:MGI:3644433 +665184 Gm7532 MGI:MGI:3644435 +665186 Gm7534 MGI:MGI:3702974|Ensembl:ENSMUSG00000073747|Vega:OTTMUSG00000010562 +665187 Gm7535 MGI:MGI:3644434 +665189 Gm7536 MGI:MGI:3645137 +665191 Gm7537 MGI:MGI:3647620 +665194 Gm7538 MGI:MGI:3647618|Ensembl:ENSMUSG00000107334 +665196 Gm7539 MGI:MGI:3647619 +665197 Gm12936 MGI:MGI:3651145 +665199 Gm13542 MGI:MGI:3649446 +665205 Gm14327 MGI:MGI:3652188 +665206 Gm7540 MGI:MGI:3648279 +665207 Gm7541 MGI:MGI:3648278 +665210 Vmn2r91 MGI:MGI:3645072|Ensembl:ENSMUSG00000091206|Vega:OTTMUSG00000039015 +665211 Gm14326 MGI:MGI:3709298|Ensembl:ENSMUSG00000078862|Vega:OTTMUSG00000016327 +665212 Gm12684 MGI:MGI:3650091 +665213 Gm7542 MGI:MGI:3645071 +665218 Gm11927 MGI:MGI:3651638 +665225 Gm7544 MGI:MGI:3779750 +665227 Vmn2r94 MGI:MGI:3648050|Ensembl:ENSMUSG00000090417|Vega:OTTMUSG00000039017 +665228 Gm11928 MGI:MGI:3651635 +665232 Gm11929 MGI:MGI:3651490 +665233 Gm7545 MGI:MGI:3644882 +665234 Gm7546 MGI:MGI:3644883 +665235 Gm7547 MGI:MGI:3644884 +665237 Rpsa-ps1 MGI:MGI:3644886 +665239 Gm7550 MGI:MGI:3644880 +665241 Gm7551 MGI:MGI:3648704 +665244 Gm7552 MGI:MGI:3648702 +665245 Gm12944 MGI:MGI:3650498 +665246 Gm7553 MGI:MGI:3826364 +665247 Gm7554 MGI:MGI:3646122 +665250 Gm11401 MGI:MGI:3649407 +665254 Gm7556 MGI:MGI:3645467 +665255 Vmn2r28 MGI:MGI:3645468|Ensembl:ENSMUSG00000066820|Vega:OTTMUSG00000036955 +665256 Gm7557 MGI:MGI:3645465 +665258 Gm7558 MGI:MGI:3645515 +665260 Gm7559 MGI:MGI:3648486 +665262 Gm7560 MGI:MGI:3648484 +665264 Gm14314 MGI:MGI:3651072 +665267 Gm7561 MGI:MGI:3648480 +665268 1600029O15Rik MGI:MGI:3045362|Ensembl:ENSMUSG00000057818 +665270 Plb1 MGI:MGI:1922406|Ensembl:ENSMUSG00000029134|Vega:OTTMUSG00000024343 +665271 Gm7562 MGI:MGI:3645249|Ensembl:ENSMUSG00000109623 +665276 Gm20772 MGI:MGI:5434128|Ensembl:ENSMUSG00000102739|Vega:OTTMUSG00000049725 +665277 Gm11970 MGI:MGI:3650056 +665279 Gm7565 MGI:MGI:3645254 +665280 Gm7566 MGI:MGI:3649155 +665281 Rps12-ps22 MGI:MGI:3649154 +665282 Gm7568 MGI:MGI:3649156 +665283 Gm11971 MGI:MGI:3650054 +665284 Gm7569 MGI:MGI:3649158 +665285 Gm7570 MGI:MGI:3649157 +665287 Gm12990 MGI:MGI:3651107 +665288 Gm7571 MGI:MGI:3649152 +665290 LOC665290 Ensembl:ENSMUSG00000094337 +665291 Gm7572 MGI:MGI:3645867 +665292 Vmn2r-ps115 MGI:MGI:3761533 +665294 Gm7573 MGI:MGI:3645862 +665296 Gm7575 MGI:MGI:3645860 +665298 Gm11942 MGI:MGI:3650608 +665301 Gm20773 MGI:MGI:5434129|Ensembl:ENSMUSG00000095900|Vega:OTTMUSG00000050539 +665302 Gm7577 MGI:MGI:3646748 +665303 Vmn2r-ps117 MGI:MGI:3761535 +665305 Gm7579 MGI:MGI:3647476 +665306 3930402G23Rik MGI:MGI:1921277|Ensembl:ENSMUSG00000038917 +665310 Gm7581 MGI:MGI:3643855 +665314 Gm11980 MGI:MGI:3651802 +665315 Gm13397 MGI:MGI:3651605 +665317 Gm7582 MGI:MGI:3643856 +665319 Gm7583 MGI:MGI:3779751 +665321 Gm7584 MGI:MGI:3647027 +665325 Rps12-ps23 MGI:MGI:3647025 +665327 Gm11975 MGI:MGI:3650057 +665328 Gm7587 MGI:MGI:3647021 +665329 Gm7588 MGI:MGI:3647022 +665330 Gm7589 MGI:MGI:3644073 +665331 Rhox7-ps1 MGI:MGI:3643148 +665333 Gm7591 MGI:MGI:3644074 +665334 Gm12988 MGI:MGI:3650876 +665338 Gm7592 MGI:MGI:3644077 +665339 Gm11977 MGI:MGI:3650690 +665341 Gm7593 MGI:MGI:3647262 +665342 Gm7594 MGI:MGI:3647263 +665343 Gm11983 MGI:MGI:3650519 +665344 Vmn2r-ps119 MGI:MGI:3761537 +665348 Gm7595 MGI:MGI:3647265 +665350 Gm7596 MGI:MGI:3644314 +665352 Gm7598 MGI:MGI:3644312 +665356 Gm7599 MGI:MGI:3644309 +665359 Vmn2r-ps153 MGI:MGI:3761713 +665362 Gm12791 MGI:MGI:3649397 +665363 Gm7600 MGI:MGI:3647502 +665364 Rps12-ps20 MGI:MGI:3647506 +665366 Rpl18a-ps1 MGI:MGI:3647504 +665367 Gm12350 MGI:MGI:3649478 +665369 Ap3s1-ps1 MGI:MGI:1929216 +665370 Gm7604 MGI:MGI:3644542 +665371 Gm7605 MGI:MGI:3644541 +665372 Gm15778 MGI:MGI:3783220 +665374 Gm7607 MGI:MGI:3644538|Ensembl:ENSMUSG00000111085 +665376 Vmn2r99 MGI:MGI:3644540|Ensembl:ENSMUSG00000090304|Vega:OTTMUSG00000039759 +665378 Gm7609 MGI:MGI:3644536 +665380 Gm11989 MGI:MGI:3702318 +665381 Gm7611 MGI:MGI:3647727 +665382 Gm7612 MGI:MGI:3647728 +665385 Gm7613 MGI:MGI:3647731 +665386 Gm7614 MGI:MGI:3647732 +665389 Gm7616 MGI:MGI:3647735 +665391 Gm7617 MGI:MGI:3644738 +665395 Gm7618 MGI:MGI:3644742 +665396 Gm7619 MGI:MGI:3644741 +665399 Gm7621 MGI:MGI:3644745 +665401 Gm7622 MGI:MGI:3647115 +665402 Gm7623 MGI:MGI:3647114 +665405 Gm7624 MGI:MGI:3647111 +665407 Rpl5-ps1 MGI:MGI:3647110 +665409 Gm7626 MGI:MGI:3647116 +665410 Gm7627 MGI:MGI:3643954 +665412 Rpsa-ps9 MGI:MGI:3650393 +665413 Gm7628 MGI:MGI:3643956 +665415 Gm7629 MGI:MGI:3643952 +665416 Rps19-ps9 MGI:MGI:3641929 +665419 Rab11b-ps2 MGI:MGI:3643959 +665424 Gm7631 MGI:MGI:3644524 +665426 Gm15782 MGI:MGI:3783224 +665431 Gm7633 MGI:MGI:3644196 +665433 Hist1h2ao MGI:MGI:2448302|Ensembl:ENSMUSG00000094248|Vega:OTTMUSG00000000457 +665434 Gm7634 MGI:MGI:3644198 +665436 Gm11524 MGI:MGI:3651807 +665441 Gm15786 MGI:MGI:3783228 +665442 Vmn2r-ps36 MGI:MGI:3757689 +665443 LOC665443 MGI:MGI:3646609 +665450 Gm7638 MGI:MGI:3643470 +665451 Gm12716 MGI:MGI:3650738 +665453 Gm7639 MGI:MGI:3645906 +665454 Gm11271 MGI:MGI:3652214 +665455 Gm7640 MGI:MGI:3644246 +665461 Gm7642 MGI:MGI:3646872 +665463 Rps12-ps12 MGI:MGI:3646874 +665466 Gm7644 MGI:MGI:3646878 +665468 Gm7646 MGI:MGI:3646880 +665469 Gm7647 MGI:MGI:3779753 +665470 Gm7648 MGI:MGI:3643736 +665472 Rpl19-ps2 MGI:MGI:3643734 +665473 Gm7650 MGI:MGI:3643735 +665474 Gm7651 MGI:MGI:3643732 +665476 Gm7652 MGI:MGI:3643731 +665478 Gm7653 MGI:MGI:3643729 +665480 Gm7654 MGI:MGI:3648037 +665485 Vmn2r-ps38 MGI:MGI:3757702 +665486 Gm7656 MGI:MGI:3648032 +665488 Gm7657 MGI:MGI:3648030 +665489 Gm7658 MGI:MGI:3648029 +665495 Vmn2r-ps40 MGI:MGI:3757865 +665497 Gm7662 MGI:MGI:3779754 +665499 Gm7663 MGI:MGI:3779755 +665503 Gm7664 MGI:MGI:3645656 +665506 LOC665506 - +665509 Gm7665 MGI:MGI:3645651 +665511 Gm7666 MGI:MGI:3648907 +665513 Gm7667 MGI:MGI:3648908 +665516 Gm7669 MGI:MGI:3648911 +665518 Gm12723 MGI:MGI:3652213 +665519 Gm7670 MGI:MGI:3648912 +665520 Gm12382 MGI:MGI:3651853 +665521 BC080696 MGI:MGI:3770624 +665522 Rps12-ps15 MGI:MGI:3645463 +665523 Gm7672 MGI:MGI:3647232 +665524 Tubb2a-ps1 MGI:MGI:3647236 +665525 Vmn1r224 MGI:MGI:3645524|Ensembl:ENSMUSG00000091151|Vega:OTTMUSG00000039778 +665526 Gm7674 MGI:MGI:3645525 +665533 Rpl31-ps10 MGI:MGI:3650100 +665535 Gm7675 MGI:MGI:3648706 +665536 Gm7676 MGI:MGI:3644053 +665538 Gm14489 MGI:MGI:3649726 +665539 Vmn2r-ps43 MGI:MGI:3757874 +665543 Gm7678 MGI:MGI:3647136 +665548 Gm7680 MGI:MGI:3646083 +665549 Gm7681 MGI:MGI:3646084 +665550 Gm20775 MGI:MGI:5434131 +665551 Gm7682 MGI:MGI:3779756 +665552 Vmn2r-ps44 MGI:MGI:3757875 +665553 Gm7684 MGI:MGI:3644097 +665556 Gm7686 MGI:MGI:3643124 +665561 Gm7688 MGI:MGI:3645865 +665562 Rpl31-ps12 MGI:MGI:3645866 +665563 Mthfd2l MGI:MGI:1915871|Ensembl:ENSMUSG00000029376|Vega:OTTMUSG00000055511 +665564 Gm7690 MGI:MGI:3648169 +665565 Gm7691 MGI:MGI:3645861 +665567 Gm7692 MGI:MGI:3645863 +665570 Gm7693 MGI:MGI:3649138 +665571 Vmn2r-ps45 MGI:MGI:3757878 +665574 Gm7694 MGI:MGI:3649135|Ensembl:ENSMUSG00000102752|Vega:OTTMUSG00000049941 +665575 Gm7695 MGI:MGI:3649134 +665577 Gm7696 MGI:MGI:3649133 +665578 Gm7697 MGI:MGI:3649141|Ensembl:ENSMUSG00000106824|Vega:OTTMUSG00000056186 +665579 Rps12-ps13 MGI:MGI:3649140 +665582 Vmn2r-ps46 MGI:MGI:3757881 +665585 Gm7700 MGI:MGI:3646508 +665586 Gm7701 MGI:MGI:3646506 +665591 Rpl36-ps9 MGI:MGI:3643602 +665593 Gm7704 MGI:MGI:3643604 +665596 Hist1h2bq MGI:MGI:3702051|Ensembl:ENSMUSG00000069307|Vega:OTTMUSG00000013203 +665598 Vmn2r-ps47 MGI:MGI:3757886 +665599 Gm7706 MGI:MGI:3643599 +665601 Gm7707 MGI:MGI:3646976 +665602 Gm7708 MGI:MGI:3644557 +665603 Gm7709 MGI:MGI:3646978 +665610 Gm7710 MGI:MGI:3644623 +665611 Rps12-ps14 MGI:MGI:3646259 +665612 Gm7712 MGI:MGI:3646255 +665613 Gm7713 MGI:MGI:3644622 +665615 Gm7714 MGI:MGI:3646267|Ensembl:ENSMUSG00000090302|Vega:OTTMUSG00000055381 +665618 Gm7715 MGI:MGI:3644631 +665620 Gm20776 MGI:MGI:5434132 +665622 Hist1h2br MGI:MGI:3710645|Ensembl:ENSMUSG00000069303|Vega:OTTMUSG00000000449 +665624 Gm7718 MGI:MGI:3644970 +665625 Vmn2r-ps51 MGI:MGI:3757931 +665628 Gm7719 MGI:MGI:3647602 +665629 Gm7720 MGI:MGI:3647601 +665630 Gm12390 MGI:MGI:3650810 +665631 Gm7721 MGI:MGI:3644419 +665632 Gm7722 MGI:MGI:3644420 +665634 Gm11278 MGI:MGI:3651908 +665635 Gm14486 MGI:MGI:3649723 +665638 Gm7724 MGI:MGI:3644412 +665641 Gm7726 MGI:MGI:3647356 +665643 Gm13386 MGI:MGI:3650788 +665644 Gm7727 MGI:MGI:3647359 +665646 Gm7729 MGI:MGI:3647361 +665649 Gm7730 MGI:MGI:3647355 +665653 Gm7731 MGI:MGI:3644153 +665654 Gm7732 MGI:MGI:3643625 +665655 Gm7733 MGI:MGI:3643628 +665658 Gm7734 MGI:MGI:3644157 +665660 Gm12011 MGI:MGI:3651574 +665662 Gm7736 MGI:MGI:3647086 +665665 Gm7739 MGI:MGI:3649170 +665666 Gm7740 MGI:MGI:3647089 +665667 Gm7741 MGI:MGI:3647088 +665669 Gm7742 MGI:MGI:3647092 +665672 Gm7743 MGI:MGI:3648517 +665674 Tpi-rs10 MGI:MGI:98798 +665677 Gm7745 MGI:MGI:3779759 +665679 Gm7746 MGI:MGI:3648521 +665682 Gm7748 MGI:MGI:3646851 +665685 Ppp1r2-ps2 MGI:MGI:3647847 +665687 Gm20777 MGI:MGI:5434133|Ensembl:ENSMUSG00000094813|Vega:OTTMUSG00000046769 +665689 Gm12663 MGI:MGI:3652168 +665690 Gm11285 MGI:MGI:3651653 +665697 Gm7751 MGI:MGI:3643708 +665700 Hmcn2 MGI:MGI:2677838|Ensembl:ENSMUSG00000055632|Vega:OTTMUSG00000011967 +665703 Gm11284 MGI:MGI:3651654 +665707 Gm7753 MGI:MGI:3646264 +665709 Gm11550 MGI:MGI:3650891 +665713 Gm7754 MGI:MGI:3643337 +665717 Gm7756 MGI:MGI:3779760 +665722 Gm7758 MGI:MGI:3646484 +665725 Gm7759 MGI:MGI:3646486 +665726 Gm11295 MGI:MGI:3651595 +665728 Gm12738 MGI:MGI:3651217 +665730 Gm7760 MGI:MGI:3643584 +665731 Gm7761 MGI:MGI:3643583 +665733 Eif5al3-ps MGI:MGI:3643585 +665734 LOC665734 - +665738 Gm7762 MGI:MGI:3779761 +665741 Gm7763 MGI:MGI:3645841 +665742 Vmn2r-ps95 MGI:MGI:3761347 +665743 Gm7765 MGI:MGI:3645843 +665747 Gm15550 MGI:MGI:3782999 +665749 Gm11298 MGI:MGI:3651396 +665750 Gm7768 MGI:MGI:3649111 +665751 Gm7769 MGI:MGI:3649110 +665752 Gm7770 MGI:MGI:3649109 +665755 LOC665755 Ensembl:ENSMUSG00000096728 +665756 Gm20778 MGI:MGI:5434134 +665757 Gm7773 MGI:MGI:3649112 +665760 Gm7774 MGI:MGI:3646056 +665762 Gm7775 MGI:MGI:3646054 +665766 Gm7776 MGI:MGI:3646051 +665767 Vmn2r-ps96 MGI:MGI:3761348 +665768 Gm7778 MGI:MGI:3643174 +665769 Gsdmcl2 MGI:MGI:1925409|Ensembl:ENSMUSG00000093867 +665772 Gm7780 MGI:MGI:3644021 +665773 Gm7781 MGI:MGI:3643104 +665775 Bod1l MGI:MGI:2444804|Ensembl:ENSMUSG00000061755|Vega:OTTMUSG00000055781 +665777 Hmgb1-ps11 MGI:MGI:3643106 +665778 Gm12565 MGI:MGI:3652206 +665779 Gm7783 MGI:MGI:3643099 +665780 Zscan4b MGI:MGI:3645447|Ensembl:ENSMUSG00000095339|Vega:OTTMUSG00000060305 +665782 Gm7784 MGI:MGI:3645448 +665783 Gm7785 MGI:MGI:3645449 +665793 Gm7786 MGI:MGI:3648686 +665794 Gm7787 MGI:MGI:3648685 +665796 Gm12021 MGI:MGI:3650979 +665797 Gm7788 MGI:MGI:3648684 +665798 Gm7789 MGI:MGI:3648689 +665799 Gm7790 MGI:MGI:3648688 +665800 Gm7791 MGI:MGI:3644094 +665802 Gm7792 MGI:MGI:3704104|Ensembl:ENSMUSG00000107392|Vega:OTTMUSG00000055697 +665809 Vmn2r-ps97 MGI:MGI:3761349 +665810 Gm7798 MGI:MGI:3643377 +665811 Gm7799 MGI:MGI:3643378 +665813 Rpl19-ps7 MGI:MGI:3643382 +665815 Gm7802 MGI:MGI:3646524 +665816 Gm7803 MGI:MGI:3646089 +665819 Gm7804 MGI:MGI:3643373 +665820 Gm7805 MGI:MGI:3643359 +665821 Rpl21-ps10 MGI:MGI:3643358 +665822 Gm7807 MGI:MGI:3643361 +665823 Gm7808 MGI:MGI:3643360 +665825 Gm7809 MGI:MGI:3643362 +665828 Gm10654 MGI:MGI:3643366|Ensembl:ENSMUSG00000074252 +665829 Tubb4b-ps2 MGI:MGI:3723458 +665831 Gm7812 MGI:MGI:3646293 +665836 Gm7814 MGI:MGI:3646287 +665838 Gm7815 MGI:MGI:3646285 +665839 Gm7816 MGI:MGI:3646286 +665844 Gm7818 MGI:MGI:3643608 +665845 Gm7819 MGI:MGI:3779765 +665846 Gm7820 MGI:MGI:3643607 +665848 Zscan4e MGI:MGI:3643613 +665850 Gm7821 MGI:MGI:3646509 +665851 Gm7822 MGI:MGI:3646510 +665854 Gm7823 MGI:MGI:3645997 +665855 Gm7824 MGI:MGI:3779766 +665856 Gm7825 MGI:MGI:3646507 +665858 Gm7827 MGI:MGI:3646513 +665859 Gm14980 MGI:MGI:3646514 +665860 Trmt112-ps1 MGI:MGI:3643840 +665863 Gm7831 MGI:MGI:3643841 +665864 Gm7832 MGI:MGI:3779767 +665865 Gm7833 MGI:MGI:3643837 +665866 Gm7834 MGI:MGI:3643838 +665868 Gm12029 MGI:MGI:3651192 +665874 Gm10769 MGI:MGI:3646733 +665879 Gm7836 MGI:MGI:3646728 +665882 Gm15497 MGI:MGI:3782944 +665883 Gm7837 MGI:MGI:3644044 +665886 Gm7838 MGI:MGI:3644048 +665887 Gm7839 MGI:MGI:3644047 +665888 Gm7840 MGI:MGI:3644051 +665889 Gm7841 MGI:MGI:3644050 +665890 Gm7842 MGI:MGI:3646991 +665891 Krtap4-1 MGI:MGI:3622079|Ensembl:ENSMUSG00000063251|Vega:OTTMUSG00000002188 +665892 Bod1-ps MGI:MGI:3646992 +665902 Zscan4f MGI:MGI:3708485|Ensembl:ENSMUSG00000070828|Vega:OTTMUSG00000032641 +665903 Gm7846 MGI:MGI:3645212 +665913 Zscan4-ps2 MGI:MGI:3708487 +665916 Gm7847 MGI:MGI:3648443 +665918 LOC665918 - +665922 Gm11557 MGI:MGI:3651826 +665926 Gm7848 MGI:MGI:3645032 +665927 Gm7849 MGI:MGI:3645033|Ensembl:ENSMUSG00000079114|Vega:OTTMUSG00000019859 +665928 Gm7850 MGI:MGI:3645028 +665929 Gm7851 MGI:MGI:3648946 +665931 Rplp2-ps1 MGI:MGI:3826366 +665933 Gm7853 MGI:MGI:3648235 +665934 Gm7854 MGI:MGI:3648234|Ensembl:ENSMUSG00000085720 +665936 Gm7855 MGI:MGI:3648232 +665939 Gm7856 MGI:MGI:3648230 +665941 Gm7857 MGI:MGI:3644849 +665943 E330014E10Rik MGI:MGI:3615333|Ensembl:ENSMUSG00000072813|Vega:OTTMUSG00000055769 +665944 Gm7858 MGI:MGI:3644844 +665945 Gm7859 MGI:MGI:3646834 +665947 Gm7860 MGI:MGI:3644843 +665948 Gm13407 MGI:MGI:3650229 +665949 Gm12821 MGI:MGI:3649625 +665953 Gm12035 MGI:MGI:3651599 +665956 Gm7861 MGI:MGI:3648003|Ensembl:ENSMUSG00000079113|Vega:OTTMUSG00000019893 +665957 Gm7862 MGI:MGI:3648002 +665959 Gm7863 MGI:MGI:3647996 +665961 Vmn2r-ps128 MGI:MGI:3761685 +665964 Gm7866 MGI:MGI:3644625 +665966 Gm7867 MGI:MGI:3644627 +665967 Gm7868 MGI:MGI:3644628 +665969 Gm15303 MGI:MGI:3705378 +665970 Gm7870 MGI:MGI:3647802 +665971 Gm20780 MGI:MGI:5434136 +665972 Gm7871 MGI:MGI:3647800 +665973 Gm15571 MGI:MGI:3783019 +665974 Vmn2r-ps103 MGI:MGI:3761522 +665975 Gm7873 MGI:MGI:3647803 +665976 Vmn2r-ps129 MGI:MGI:3761688 +665977 Gm7874 MGI:MGI:3645268 +665981 Gm7876 MGI:MGI:3779769 +665985 Gm20781 MGI:MGI:5434137 +665988 Vmn2r-ps131 MGI:MGI:3761691 +665989 Gm7879 MGI:MGI:3645078 +665990 Gm7880 MGI:MGI:3645672 +665992 Krtap4-8 MGI:MGI:3652306|Ensembl:ENSMUSG00000089724|Vega:OTTMUSG00000002541 +665994 Gm7882 MGI:MGI:3647603 +665998 Krtap4-9 MGI:MGI:3652060|Ensembl:ENSMUSG00000078262|Vega:OTTMUSG00000002198 +665999 Tpt1-ps4 MGI:MGI:2664998 +666001 Rpl15-ps2 MGI:MGI:3648255 +666002 Vmn2r114 MGI:MGI:3648252|Ensembl:ENSMUSG00000091945|Vega:OTTMUSG00000039964 +666005 Gm7887 MGI:MGI:3648251 +666009 Gm7889 MGI:MGI:3648247 +666011 Gm7890 MGI:MGI:3645227 +666012 Gm7891 MGI:MGI:3645230 +666015 Gm13042 MGI:MGI:3651155 +666018 Gm13038 MGI:MGI:3650684 +666019 Gm7892 MGI:MGI:3645233 +666020 Gm7893 MGI:MGI:3648015 +666023 Gm7894 MGI:MGI:3648339 +666025 Gm7895 MGI:MGI:3648340 +666027 Gm7896 MGI:MGI:3779770 +666028 Gm7897 MGI:MGI:3648011 +666030 Gm7898 MGI:MGI:3645045 +666031 Gm7899 MGI:MGI:3645044 +666036 Gm7901 MGI:MGI:3645047 +666038 Gm7902 MGI:MGI:3645041 +666040 Gm7903 MGI:MGI:3648697|Ensembl:ENSMUSG00000096508|Vega:OTTMUSG00000018767 +666042 Gm13445 MGI:MGI:3649614 +666043 Gm7904 MGI:MGI:3648696 +666044 Gm15566 MGI:MGI:3783015 +666045 Gm7905 MGI:MGI:3648700 +666047 Gm7906 MGI:MGI:3648698 +666048 Trabd2b MGI:MGI:3650152|Ensembl:ENSMUSG00000070867|Vega:OTTMUSG00000008561 +666049 Gm13080 MGI:MGI:3650235 +666052 Vmn2r-ps109 MGI:MGI:3761528 +666053 Gm7908 MGI:MGI:3645647 +666055 Gm7909 MGI:MGI:3645643 +666056 Gm7910 MGI:MGI:3645646 +666060 Frmpd1 MGI:MGI:2446274|Ensembl:ENSMUSG00000035615|Vega:OTTMUSG00000007527 +666061 Gm7911 MGI:MGI:3644791 +666062 Gm7912 MGI:MGI:3644792 +666065 Vmn2r-ps53 MGI:MGI:3757948 +666072 Gm7916 MGI:MGI:3645430 +666073 Gm7917 MGI:MGI:3645429 +666077 Gm7919 MGI:MGI:3645426 +666078 Gm12058 MGI:MGI:3652312 +666079 Gm7920 MGI:MGI:3643409 +666084 Gm7924 MGI:MGI:3649127 +666085 Vmn2r54 MGI:MGI:3704110|Ensembl:ENSMUSG00000096593|Vega:OTTMUSG00000038269 +666093 Gm7925 MGI:MGI:3646069 +666094 Gm7926 MGI:MGI:3646071 +666096 Gm14594 MGI:MGI:3705865 +666097 Gm7927 MGI:MGI:3646072 +666098 Gm7928 MGI:MGI:3646067 +666099 Gm7929 MGI:MGI:3646066 +666100 Gm7930 MGI:MGI:3643450 +666105 Gm7932 MGI:MGI:3643446 +666107 Gm14623 MGI:MGI:3709650 +666108 Gm7933 MGI:MGI:3643452 +666111 Rpl29-ps5 MGI:MGI:3646368 +666113 Gm7935 MGI:MGI:3646370 +666114 Gm7936 MGI:MGI:3646364 +666118 Olfr335-ps MGI:MGI:3030169 +666122 Gm14595 MGI:MGI:3705820 +666125 Gm7939 MGI:MGI:3647260 +666127 Gm7940 MGI:MGI:3643723 +666128 Gm11598 MGI:MGI:3649374 +666130 Gm7941 MGI:MGI:3646600 +666133 Gm7942 MGI:MGI:3646599 +666134 Gm7943 MGI:MGI:3646604 +666135 Gm14590 MGI:MGI:3705800 +666138 Gm7945 MGI:MGI:3646596 +666141 Gm7946 MGI:MGI:3642980 +666143 Gm7947 MGI:MGI:3643163 +666144 Gm12749 MGI:MGI:3652196 +666145 1700016G14Rik MGI:MGI:1916676 +666146 Gm7948 MGI:MGI:3643172 +666150 Gm13120 MGI:MGI:3651691 +666151 Gm7950 MGI:MGI:3645943 +666152 Gm7951 MGI:MGI:3648771 +666153 Gm7952 MGI:MGI:3648772 +666155 Gm7953 MGI:MGI:3648775 +666156 Gm7954 MGI:MGI:3648778 +666157 Gm7955 MGI:MGI:3648780 +666160 Gm7957 MGI:MGI:3643208 +666161 Gm7958 MGI:MGI:3643207 +666162 Gm7959 MGI:MGI:3643210 +666164 Gm7961 MGI:MGI:3643212 +666167 Gm7962 MGI:MGI:3643213 +666168 Cyp4a31 MGI:MGI:3028580|Ensembl:ENSMUSG00000028712|Vega:OTTMUSG00000008627 +666170 Gm7964 MGI:MGI:3646150 +666173 Vps13b MGI:MGI:1916380|Ensembl:ENSMUSG00000037646 +666177 Gm7965 MGI:MGI:3646147 +666180 Nsa2-ps2 MGI:MGI:3644985 +666182 Gm7967 MGI:MGI:3644984|Ensembl:ENSMUSG00000100009 +666183 Gm7968 MGI:MGI:3644983 +666184 Gm15080 MGI:MGI:3712217|Ensembl:ENSMUSG00000072931|Vega:OTTMUSG00000018964 +666185 Gm7969 MGI:MGI:3779771 +666186 Gm7970 MGI:MGI:3644387 +666187 Gm7971 MGI:MGI:3779772|Ensembl:ENSMUSG00000094043|Vega:OTTMUSG00000055682 +666190 Gm7972 MGI:MGI:3647337 +666194 Gm13126 MGI:MGI:3651475 +666196 Gm7973 MGI:MGI:3647336 +666199 Gm7974 MGI:MGI:3644332 +666201 Gm7976 MGI:MGI:3644736 +666202 Gm7977 MGI:MGI:3648898|Ensembl:ENSMUSG00000103257 +666203 Gm7978 MGI:MGI:3704107|Ensembl:ENSMUSG00000096139|Vega:OTTMUSG00000055684 +666205 Gm7979 MGI:MGI:3648893 +666207 Gm7980 MGI:MGI:3647449 +666209 Gm7982 MGI:MGI:3648891|Ensembl:ENSMUSG00000072814|Vega:OTTMUSG00000033797 +666210 Rpl19-ps8 MGI:MGI:3645840 +666211 Gm7984 MGI:MGI:3645839 +666212 Gm11380 MGI:MGI:3650782 +666213 Gm7985 MGI:MGI:3645837 +666214 1700049E17Rik1 MGI:MGI:1920665 +666215 Gm13127 MGI:MGI:3651260 +666220 Gm7986 MGI:MGI:3649097 +666221 Gm11352 MGI:MGI:3649796 +666223 Gm7988 MGI:MGI:3649096 +666225 Pla2g4c-ps MGI:MGI:5645818 +666226 Gm7990 MGI:MGI:3649098 +666228 Gm7991 MGI:MGI:3649103 +666231 Gm7993 MGI:MGI:3647399 +666232 Rpl7a-ps14 MGI:MGI:3647425 +666233 Gm7995 MGI:MGI:3779776|Ensembl:ENSMUSG00000094157|Vega:OTTMUSG00000036346 +666237 Gm7997 MGI:MGI:3646045 +666240 Gm8000 MGI:MGI:3648432 +666242 Prdx2-rs3 MGI:MGI:1859808 +666244 Tmsb15b1 MGI:MGI:3843059|Ensembl:ENSMUSG00000089768|Vega:OTTMUSG00000034851 +666249 Gm8004 MGI:MGI:3648439 +666251 Amd-ps6 MGI:MGI:3645413 +666253 Gm8005 MGI:MGI:3645411 +666256 Zbed4-ps1 MGI:MGI:3645416 +666257 Gm8008 MGI:MGI:3645415 +666258 Gm12117 MGI:MGI:3652019 +666259 Gm15573 MGI:MGI:3783021 +666261 Gm8009 MGI:MGI:3648650 +666262 Gm8010 MGI:MGI:3648648 +666264 Gm8011 MGI:MGI:3648646 +666266 Gm8013 MGI:MGI:3648644|Ensembl:ENSMUSG00000106357 +666267 Kat6b-ps1 MGI:MGI:3648645 +666269 Gm12118 MGI:MGI:3652027 +666270 Gm12072 MGI:MGI:3650749 +666272 Gm8016 MGI:MGI:3645625|Ensembl:ENSMUSG00000113050 +666274 Rps10-ps2 MGI:MGI:3645627 +666277 Gm8019 MGI:MGI:3645628 +666279 Dspp MGI:MGI:109172|Ensembl:ENSMUSG00000053268|Vega:OTTMUSG00000042402 +666282 Gm13024 MGI:MGI:3650678 +666283 Gm8022 MGI:MGI:3647993 +666284 Gm8023 MGI:MGI:3647988 +666285 Gm8024 MGI:MGI:3647989 +666288 Gm15039 MGI:MGI:3709654 +666289 Gm8025 MGI:MGI:3647995 +666297 Gm8031 MGI:MGI:3645020 +666298 Gm8032 MGI:MGI:3645027 +666300 Gm8034 MGI:MGI:3644144 +666302 Gm8035 MGI:MGI:3644146 +666303 Gm8036 MGI:MGI:3644145 +666305 Gm15526 MGI:MGI:3782973 +666308 Gm8038 MGI:MGI:3644148 +666310 Gm8039 MGI:MGI:3647078 +666311 Zscan25 MGI:MGI:3647079|Ensembl:ENSMUSG00000070420|Vega:OTTMUSG00000055031 +666312 Obox3-ps2 MGI:MGI:3647077 +666314 Gm13228 MGI:MGI:3651932 +666315 Gm8041 MGI:MGI:3647081 +666317 Prl2c1 MGI:MGI:3649927|Ensembl:ENSMUSG00000062551|Vega:OTTMUSG00000000651 +666319 Gm8043 MGI:MGI:3647084 +666320 Gm8044 MGI:MGI:3648514 +666321 Gm8045 MGI:MGI:3643919 +666322 Gm8046 MGI:MGI:3643918 +666323 Gm8047 MGI:MGI:3648510 +666325 Gm12585 MGI:MGI:3650149 +666326 Gm8048 MGI:MGI:3648505 +666327 Gm8049 MGI:MGI:3648503 +666329 Gm3317 MGI:MGI:3781495 +666330 Gm8051 MGI:MGI:3647834 +666331 LOC666331 - +666334 Gm13234 MGI:MGI:3649926 +666337 Obox3-ps5 MGI:MGI:3779781 +666339 Muc3 MGI:MGI:1203527 +666340 Gm8054 MGI:MGI:3643693 +666342 Gm8055 MGI:MGI:3643695 +666346 Gm8056 MGI:MGI:3643698 +666348 Apol7e MGI:MGI:3704456|Ensembl:ENSMUSG00000071716 +666349 Gm13239 MGI:MGI:3650779 +666351 Gm13232 MGI:MGI:3649252 +666352 Obox3-ps1 MGI:MGI:3646564 +666353 Gm8058 MGI:MGI:3646565 +666358 Vmn2r-ps72 MGI:MGI:3761317 +666359 Gm8061 MGI:MGI:3646568 +666360 Gm8062 MGI:MGI:3643433 +666361 Vmn2r-ps74 MGI:MGI:3761319 +666365 Obox3-ps3 MGI:MGI:3779782 +666367 Dppa5b MGI:MGI:3765340 +666370 Gm8065 MGI:MGI:3646349 +666372 Gm8066 MGI:MGI:3646351 +666373 Dppa5c MGI:MGI:3765342 +666374 Gm8067 MGI:MGI:3646352 +666376 Gm8068 MGI:MGI:3646354 +666377 Gm8069 MGI:MGI:3645115 +666379 Gm12445 MGI:MGI:3650256 +666381 Obox3-ps4 MGI:MGI:3643193 +666382 Vmn2r-ps80 MGI:MGI:3761325 +666383 Gm8074 MGI:MGI:3643195 +666385 Gm8075 MGI:MGI:3643190 +666386 Gm13233 MGI:MGI:3649253 +666388 Gm8077 MGI:MGI:3643188 +666389 Gm12447 MGI:MGI:3650247 +666390 Gm13237 MGI:MGI:3649924 +666391 Rps8-ps3 MGI:MGI:3646130 +666392 Gm8079 MGI:MGI:3646128 +666393 Gm12838 MGI:MGI:3649431 +666394 Gm8080 MGI:MGI:3646133 +666396 Gm8082 MGI:MGI:3646131 +666397 Gm8083 MGI:MGI:3646132 +666401 Gm8084 MGI:MGI:3645945 +666403 Gm12091 MGI:MGI:3650089 +666405 Gm8085 MGI:MGI:3645949 +666407 Mrip-ps MGI:MGI:3645947 +666408 Gm8087 MGI:MGI:3645940 +666411 Gm11585 MGI:MGI:3651395 +666413 Gm8088 MGI:MGI:3642983 +666414 Gm8089 MGI:MGI:3642979 +666417 Gm8091 MGI:MGI:3643169 +666418 Vmn2r-ps83 MGI:MGI:3761328 +666419 Gm8093 MGI:MGI:3642975 +666420 Gm8094 MGI:MGI:3645750 +666422 Gm8096 MGI:MGI:3645752|Ensembl:ENSMUSG00000110372 +666424 Gm8097 MGI:MGI:3645746 +666427 Gm8098 MGI:MGI:3645749 +666429 Gm8099 MGI:MGI:3645754 +666430 Gm8100 MGI:MGI:3649005 +666431 Gm8101 MGI:MGI:3649004 +666432 Gm8102 MGI:MGI:3649003 +666436 Gm8104 MGI:MGI:3649000 +666440 Gm8106 MGI:MGI:3645535 +666441 Gm8107 MGI:MGI:3645536 +666443 Gm11370 MGI:MGI:3651832 +666444 Gm8109 MGI:MGI:3645533 +666446 Gm8110 MGI:MGI:3645532 +666447 Gm8111 MGI:MGI:3646092 +666448 Gm8112 MGI:MGI:3645531 +666451 Gm8113 MGI:MGI:3648791 +666452 Gm12097 MGI:MGI:3651582 +666454 Gm8114 MGI:MGI:3648795 +666455 Gm8115 MGI:MGI:3648794 +666456 Gm8116 MGI:MGI:3648797 +666457 G370120E05Rik MGI:MGI:3648796 +666459 Gm8118 MGI:MGI:3648798 +666465 Gm8121 MGI:MGI:3645325 +666468 Atg4a MGI:MGI:2147903|Ensembl:ENSMUSG00000079418|Vega:OTTMUSG00000018921 +666470 Gm12099 MGI:MGI:3651579 +666471 Gm8122 MGI:MGI:3648566 +666473 Gm12430 MGI:MGI:3651061 +666474 Gm13167 MGI:MGI:3650208 +666478 Rps2-ps12 MGI:MGI:3648563 +666479 Gm8125 MGI:MGI:3648562 +666480 Gm13063 MGI:MGI:3649474 +666481 Gm8126 MGI:MGI:3646861 +666482 Gm13169 MGI:MGI:3651793 +666483 Gm12470 MGI:MGI:3652113 +666485 Gm8127 MGI:MGI:3646865 +666486 Gm8128 MGI:MGI:3646862 +666487 Gm8129 MGI:MGI:3646863 +666488 Gm15294 MGI:MGI:3708114 +666489 Gm8130 MGI:MGI:3647919 +666490 Gm8131 MGI:MGI:3643946 +666491 Gm8132 MGI:MGI:3643945 +666493 Gm8134 MGI:MGI:3648559 +666495 Gm13181 MGI:MGI:3650464 +666498 Gm13149 MGI:MGI:3651738 +666501 Gm8137 MGI:MGI:3647467 +666502 Gm8138 MGI:MGI:3647466 +666503 Gm8139 MGI:MGI:3644955 +666504 Tmem249 MGI:MGI:3647471 +666505 Gm16490 MGI:MGI:3704483 +666508 Gm8141 MGI:MGI:3647473 +666513 Gm11787 MGI:MGI:3702103 +666514 Gm13160 MGI:MGI:3649984 +666516 Gm8143 MGI:MGI:3644270 +666517 Gm8144 MGI:MGI:3644271 +666518 Gm8145 MGI:MGI:3644272 +666519 Gm8146 MGI:MGI:3644273 +666528 Zfp541 MGI:MGI:3647699|Ensembl:ENSMUSG00000078796|Vega:OTTMUSG00000060704 +666529 Gm8149 MGI:MGI:3647698 +666531 Gm13456 MGI:MGI:3651389 +666532 Zfp991 MGI:MGI:3701604|Ensembl:ENSMUSG00000067916|Vega:OTTMUSG00000010657 +666533 Vmn2r-ps24 MGI:MGI:3761469 +666534 Gm8151 MGI:MGI:3644503 +666535 Gm8152 MGI:MGI:3644504 +666537 Gm8153 MGI:MGI:3644502 +666539 Gm8154 MGI:MGI:3644509 +666540 Gm15197 MGI:MGI:3708123 +666541 Gm8155 MGI:MGI:3647889 +666543 Gm8157 MGI:MGI:3647695 +666545 Gm15616 MGI:MGI:3783061 +666546 Gm13163 MGI:MGI:3651199 +666548 Gm8158 MGI:MGI:3647883 +666549 Gm8159 MGI:MGI:3647882 +666553 Gm15528 MGI:MGI:3782975 +666556 Gm8161 MGI:MGI:3644714 +666557 Gm13158 MGI:MGI:3649982 +666558 Gm8162 MGI:MGI:3644710 +666559 Gm8163 MGI:MGI:3644711 +666560 Gm8164 MGI:MGI:3648127 +666561 Gm8165 MGI:MGI:3648126 +666564 Gm8167 MGI:MGI:3644250 +666568 Gm8168 MGI:MGI:3648130 +666571 Gm8170 MGI:MGI:3644928 +666574 Gm13144 MGI:MGI:3651743 +666576 Gm8171 MGI:MGI:3644929 +666577 Gm8172 MGI:MGI:3644930 +666578 Gm8173 MGI:MGI:3648321 +666579 Gm8174 MGI:MGI:3648322 +666581 Zfp988 MGI:MGI:3651985 +666582 Gm8176 MGI:MGI:3646477 +666584 BC024063 MGI:MGI:2670978|Ensembl:ENSMUSG00000112160 +666585 Gm8177 MGI:MGI:3805962 +666586 Gm11808 MGI:MGI:3649356 +666588 Gm8178 MGI:MGI:3646475 +666589 Gm8179 MGI:MGI:3646474 +666590 Gm8180 MGI:MGI:3643326 +666594 Gm8181 MGI:MGI:3643329 +666596 Gm12857 MGI:MGI:3652230 +666597 Gm8182 MGI:MGI:3643331 +666598 Gm8183 MGI:MGI:3643325 +666599 Gm13216 MGI:MGI:3651709 +666601 Gm8184 MGI:MGI:3643112 +666602 Gm12453 MGI:MGI:3650226 +666603 Gm15740 MGI:MGI:3783182 +666604 Gm13466 MGI:MGI:3649597 +666607 Gm8185 MGI:MGI:3643116 +666609 Gm8186 MGI:MGI:3643110 +666611 Gm8188 MGI:MGI:3646272 +666612 Gm8189 MGI:MGI:3779786 +666613 Gm11604 MGI:MGI:3651795 +666614 Gm8190 MGI:MGI:3646277 +666616 Gm8192 MGI:MGI:3644706 +666617 Gm12452 MGI:MGI:3650619 +666618 Gm13155 MGI:MGI:3651982 +666620 Gm12110 MGI:MGI:3649342 +666621 Gm8194 MGI:MGI:3643352 +666624 Gm8197 MGI:MGI:3643349 +666628 Gm8199 MGI:MGI:3643345 +666629 Gm8200 MGI:MGI:3643346 +666630 Gm8201 MGI:MGI:3646495 +666633 Gm8202 MGI:MGI:3646496 +666634 Gm8203 MGI:MGI:3646499 +666635 Gm8204 MGI:MGI:3646498 +666637 Gm8206 MGI:MGI:3779788 +666638 Gm8207 MGI:MGI:3646502 +666639 Gm8208 MGI:MGI:3646501 +666640 Gm13137 MGI:MGI:3649289 +666641 Gm8209 MGI:MGI:3643592 +666642 Gm8210 MGI:MGI:3643593 +666646 Gm12115 MGI:MGI:3652288 +666647 Gm8212 MGI:MGI:3643591 +666648 Gm8213 MGI:MGI:3643597 +666649 Gm8214 MGI:MGI:3646554 +666652 Gm13148 MGI:MGI:3651741 +666654 Gm8215 MGI:MGI:3646719 +666655 Gm8216 MGI:MGI:3646718 +666656 Gm8217 MGI:MGI:3646717 +666659 Gm8219 MGI:MGI:3646725 +666660 Gm8220 MGI:MGI:3643828 +666661 Gm8221 MGI:MGI:3779789 +666663 Gm12458 MGI:MGI:3650856 +666665 Gm8222 MGI:MGI:3643833 +666667 Gm8224 MGI:MGI:3643831 +666668 Gm8225 MGI:MGI:3643826 +666669 Gm8226 MGI:MGI:3643827 +666670 Gm8227 MGI:MGI:3648589 +666672 Gm8228 MGI:MGI:3646986 +666675 Gm8229 MGI:MGI:3646979 +666677 Gm8231 MGI:MGI:3646981 +666678 Gm8232 MGI:MGI:3648583 +666679 Gm8233 MGI:MGI:3646977 +666680 Gm8234 MGI:MGI:3779790 +666681 Gm12460 MGI:MGI:3650440 +666682 Rps2-ps9 MGI:MGI:3644037 +666684 Gm8237 MGI:MGI:3644039 +666686 Gm8238 MGI:MGI:3644041 +666688 Gm8239 MGI:MGI:3644042 +666690 Gm8241 MGI:MGI:3647219 +666693 Gm8242 MGI:MGI:3647216 +666695 Gm8244 MGI:MGI:3647222 +666697 Gm8245 MGI:MGI:3647220 +666700 Gm11804 MGI:MGI:3650654 +666703 Gm12864 MGI:MGI:3649273 +666704 Samd1 MGI:MGI:2142433|Ensembl:ENSMUSG00000079003 +666706 Gm8246 MGI:MGI:3644639|Ensembl:ENSMUSG00000095797|Vega:OTTMUSG00000042523 +666707 Gm8247 MGI:MGI:3644638 +666711 Gm8249 MGI:MGI:3647617 +666712 Gm8250 MGI:MGI:3647615 +666713 Gm8251 MGI:MGI:3647616 +666717 Gm8253 MGI:MGI:3647612 +666718 Gm8254 MGI:MGI:3647610 +666719 Gm12527 MGI:MGI:3651542 +666721 Gm11663 MGI:MGI:3651529 +666722 Gm8255 MGI:MGI:3644426 +666723 Gm8256 MGI:MGI:3779791 +666724 Gm12475 MGI:MGI:3649584 +666725 Gm8257 MGI:MGI:3644430 +666726 Gm8258 MGI:MGI:3644429 +666729 Gm8260 MGI:MGI:3644424 +666730 Gm8261 MGI:MGI:3647364 +666731 Trim43c MGI:MGI:3647365|Ensembl:ENSMUSG00000067399|Vega:OTTMUSG00000045609 +666737 4632427E13Rik MGI:MGI:1915436|Ensembl:ENSMUSG00000074024 +666738 Gm8264 MGI:MGI:3647363 +666739 Gm11662 MGI:MGI:3651457 +666743 Gm8266 MGI:MGI:3644534 +666744 Gm8267 MGI:MGI:3648993|Ensembl:ENSMUSG00000091923|Vega:OTTMUSG00000036406 +666746 Gm8268 MGI:MGI:3648998 +666747 Trim43b MGI:MGI:3648996|Ensembl:ENSMUSG00000079162|Vega:OTTMUSG00000045615 +666748 Gm8270 MGI:MGI:3648990 +666749 Gm11623 MGI:MGI:3649731 +666750 Gm8271 MGI:MGI:3648017|Ensembl:ENSMUSG00000079380|Vega:OTTMUSG00000036255 +666752 Gm8273 MGI:MGI:3648337 +666753 Gm8274 MGI:MGI:3648016 +666754 Gm8275 MGI:MGI:3648021 +666756 Gm8276 MGI:MGI:3648019 +666758 Gm8277 MGI:MGI:3648013 +666760 Gm11809 MGI:MGI:3650709 +666761 Gm12482 MGI:MGI:3651627 +666764 Gm8278 MGI:MGI:3644857 +666765 Gm8279 MGI:MGI:3779794|Ensembl:ENSMUSG00000079378|Vega:OTTMUSG00000036252 +666766 Gm12955 MGI:MGI:3652228 +666771 Gm11620 MGI:MGI:3650770 +666772 Gm8281 MGI:MGI:3647811 +666774 Rpsa-ps12 MGI:MGI:3651234 +666777 Gm8282 MGI:MGI:3647809 +666778 Gm8283 MGI:MGI:3647814 +666781 Gm13487 MGI:MGI:3650141 +666782 Rps18-ps2 MGI:MGI:3652274 +666783 Gm8285 MGI:MGI:3645456 +666786 Gm8288 MGI:MGI:3645459 +666788 Gm15770 MGI:MGI:3783212 +666789 Gm8289 MGI:MGI:3645453 +666790 Gm8290 MGI:MGI:3648461 +666792 Gm8291 MGI:MGI:3648459 +666793 Gm8292 MGI:MGI:3648460 +666794 Rbm24 MGI:MGI:3610364|Ensembl:ENSMUSG00000038132 +666797 Rpl31-ps23 MGI:MGI:3648456 +666798 Gm8295 MGI:MGI:3648465 +666799 Gm8296 MGI:MGI:3648466 +666800 Gm8297 MGI:MGI:3643799 +666802 Gm13500 MGI:MGI:3650380 +666803 Gm8298 MGI:MGI:3643798|Ensembl:ENSMUSG00000095522 +666806 Gm8300 MGI:MGI:3643794|Ensembl:ENSMUSG00000079034|Vega:OTTMUSG00000042990 +666808 Gm10410 MGI:MGI:3704422 +666809 Gm8302 MGI:MGI:3643802 +666810 Gm13494 MGI:MGI:3651037 +666812 Gm8303 MGI:MGI:3646943 +666814 Gm8304 MGI:MGI:3646945 +666815 Gm8305 MGI:MGI:3646944 +666819 Gm8307 MGI:MGI:3646941 +666822 Vmn1r-ps11 MGI:MGI:3643544 +666823 Gm8309 MGI:MGI:3643545 +666824 Gm8310 MGI:MGI:3643546 +666828 Gm8312 MGI:MGI:3643550 +666831 Gm8314 MGI:MGI:3646690 +666834 Gm8317 MGI:MGI:3646695 +666835 Gm8318 MGI:MGI:3646694 +666836 Gm8319 MGI:MGI:3646693 +666837 Gm8320 MGI:MGI:3646692 +666838 Gm8321 MGI:MGI:3646697 +666840 Gm11814 MGI:MGI:3650512 +666842 Gm14692 MGI:MGI:3713084|Ensembl:ENSMUSG00000079577|Vega:OTTMUSG00000017728 +666844 Gm8323 MGI:MGI:3646015 +666850 Gm15493 MGI:MGI:3782939 +666851 Gm8324 MGI:MGI:3647431 +666853 Gm8325 MGI:MGI:3644852 +666854 Gm15794 MGI:MGI:3783236 +666855 Gm8326 MGI:MGI:3644839 +666856 Gm8327 MGI:MGI:3644662 +666857 Gm8328 MGI:MGI:3644661 +666858 Rps11-ps5 MGI:MGI:3647437 +666859 Gm8330 MGI:MGI:3644864 +666861 Gm8331 MGI:MGI:3649049 +666862 Gm8332 MGI:MGI:3644018 +666864 Gm8334 MGI:MGI:3648921 +666866 Gm14701 MGI:MGI:3644014 +666869 Gm8337 MGI:MGI:3644012 +666870 Gm8338 MGI:MGI:3647186 +666872 Gm13501 MGI:MGI:3649893 +666873 Gm8339 MGI:MGI:3647184 +666874 Gm8340 MGI:MGI:3647183 +666875 Gm8341 MGI:MGI:3647182 +666876 Gm13503 MGI:MGI:3649895 +666877 Gm8342 MGI:MGI:3643490 +666881 Gm8343 MGI:MGI:3649108 +666882 Gm8344 MGI:MGI:3649105 +666883 Gm8345 MGI:MGI:3649106 +666887 Gm15532 MGI:MGI:3782981 +666888 Gm8346 MGI:MGI:3648741 +666891 Gm8349 MGI:MGI:3643135 +666892 Gm8350 MGI:MGI:3646046 +666893 Vmn1r-ps17 MGI:MGI:3643137 +666894 Gm8352 MGI:MGI:3646048 +666895 Gm8353 MGI:MGI:3643142 +666897 Gm11830 MGI:MGI:3649825 +666899 Gm12191 MGI:MGI:3651293 +666901 Tpt1-ps2 MGI:MGI:2664996 +666903 Gm8354 MGI:MGI:3645192 +666904 Gm8355 MGI:MGI:3645191 +666907 Ms4a4a MGI:MGI:3643932|Ensembl:ENSMUSG00000101389|Vega:OTTMUSG00000047103 +666909 Gm8357 MGI:MGI:3645186 +666911 Gm8358 MGI:MGI:3648202 +666913 Gm13505 MGI:MGI:3650158 +666914 Gm8359 MGI:MGI:3648197 +666918 Gm8362 MGI:MGI:3648195 +666919 Gm8363 MGI:MGI:3648196 +666920 Gm8364 MGI:MGI:3645200 +666921 Gm12886 MGI:MGI:3651888|Ensembl:ENSMUSG00000078576|Vega:OTTMUSG00000008908 +666922 Gm8365 MGI:MGI:3647827 +666923 Gm8366 MGI:MGI:3645202 +666924 Gm8367 MGI:MGI:3645196 +666926 Gm8369 MGI:MGI:3645380|Ensembl:ENSMUSG00000058470|Vega:OTTMUSG00000047182 +666927 Gm12887 MGI:MGI:3652131|Ensembl:ENSMUSG00000078575|Vega:OTTMUSG00000008910 +666928 Vmn1r-ps20 MGI:MGI:3645210 +666931 Gm10573 MGI:MGI:3649909 +666933 Gm8371 MGI:MGI:3644592 +666936 Gm14032 MGI:MGI:3650861 +666937 Gm12892 MGI:MGI:3649649 +666938 Bend4 MGI:MGI:3648414|Ensembl:ENSMUSG00000092060|Vega:OTTMUSG00000055808 +666942 Gm8373 MGI:MGI:3644812 +666944 Gm13188 MGI:MGI:3650857 +666945 Gm10638 MGI:MGI:3704316 +666947 Gm8374 MGI:MGI:3647524 +666948 Gm8375 MGI:MGI:3644819 +666951 Gm8376 MGI:MGI:3647776 +666953 Gm12516 MGI:MGI:3651353 +666954 Vmn1r-ps22 MGI:MGI:3647778 +666955 Gm8378 MGI:MGI:3646777 +666957 Gm8379 MGI:MGI:3646778 +666959 Gm8381 MGI:MGI:3647783 +666961 Gm8383 MGI:MGI:3644995 +666962 Gm8384 MGI:MGI:3648814 +666963 Gm8385 MGI:MGI:3648812 +666966 Gm8387 MGI:MGI:3645002 +666967 Gm8388 MGI:MGI:3645001 +666968 Gm8389 MGI:MGI:3648805 +666969 Gm8390 MGI:MGI:3648802 +666970 Gm8391 MGI:MGI:3648160 +666971 Gm8392 MGI:MGI:3648162 +666973 Gm13176 MGI:MGI:3651289 +666974 Gm8394 MGI:MGI:3647964 +666976 Gm8396 MGI:MGI:3648154 +666978 Gm8398 MGI:MGI:3648175 +666979 Gm8399 MGI:MGI:3647971 +666981 Gm8401 MGI:MGI:3644368 +666982 Gm8402 MGI:MGI:3644367 +666983 Gm8403 MGI:MGI:3644366 +666987 Gm8407 MGI:MGI:3644362 +666989 Gm8408 MGI:MGI:3644370 +666993 Gm8410 MGI:MGI:3647321 +666997 Gm8412 MGI:MGI:3647318 +667000 Gm8415 MGI:MGI:3648865 +667003 Gm11675 MGI:MGI:3650970 +667005 Gm8416 MGI:MGI:3648867 +667006 Gm8417 MGI:MGI:3648869 +667010 Gm8419 MGI:MGI:3645596 +667013 Gm14730 MGI:MGI:3705542 +667014 Gm8420 MGI:MGI:3645594 +667017 Gm8421 MGI:MGI:3645593 +667019 Gm8423 MGI:MGI:3645600 +667021 Gm8424 MGI:MGI:3646584 +667023 Gm8425 MGI:MGI:3645899 +667026 Gm13534 MGI:MGI:3651249 +667027 Rps12-ps7 MGI:MGI:3648636 +667028 Gm8428 MGI:MGI:3648643 +667030 Slc25a5-ps MGI:MGI:3645403 +667031 Vmn2r-ps5 MGI:MGI:3645404 +667034 Pnp2 MGI:MGI:3712328|Ensembl:ENSMUSG00000068417|Vega:OTTMUSG00000034665 +667035 Gm8430 MGI:MGI:3645406 +667037 Gm12165 MGI:MGI:3650634 +667039 Gm13172 MGI:MGI:3650871 +667040 Gm8432 MGI:MGI:3645816 +667041 Gm8433 MGI:MGI:3643054 +667046 Gm8435 MGI:MGI:3643053 +667048 Gm14130 MGI:MGI:3652217 +667049 Gm12539 MGI:MGI:3650716 +667052 Gm8436 MGI:MGI:3642972 +667055 Gm9992 MGI:MGI:3712668|Ensembl:ENSMUSG00000056133 +667056 Gm8437 MGI:MGI:3642987 +667059 Gm8438 MGI:MGI:3646033 +667060 Vmn2r5 MGI:MGI:3649074|Ensembl:ENSMUSG00000068999|Vega:OTTMUSG00000039835 +667062 Gm13545 MGI:MGI:3649667 +667063 Gm8439 MGI:MGI:3648581|Ensembl:ENSMUSG00000091297 +667064 Gm12904 MGI:MGI:3650403 +667065 Cyp3a63-ps MGI:MGI:3717142 +667067 Vmn1r91 MGI:MGI:3649070|Ensembl:ENSMUSG00000095201|Vega:OTTMUSG00000038183 +667069 Vmn2r6 MGI:MGI:3649068|Ensembl:ENSMUSG00000090581|Vega:OTTMUSG00000039836 +667073 Gm8444 MGI:MGI:3645809 +667077 Gm8445 MGI:MGI:3647926 +667079 Gm8446 MGI:MGI:3645802 +667080 Gm12987 MGI:MGI:3649751 +667081 Gm8447 MGI:MGI:3647954 +667087 Vmn2r-ps21 MGI:MGI:3761376 +667088 Gm8449 MGI:MGI:3647960 +667090 Gm8451 MGI:MGI:3644810|Ensembl:ENSMUSG00000099471 +667094 Gm8453 MGI:MGI:3644807|Ensembl:ENSMUSG00000094149|Vega:OTTMUSG00000038126 +667098 Gm8454 MGI:MGI:3644804 +667099 Nasp-ps1 MGI:MGI:3644805 +667100 Rpl18-ps1 MGI:MGI:98018 +667101 Gm8456 MGI:MGI:3647453 +667103 Gm13570 MGI:MGI:3649720 +667104 Gm8458 MGI:MGI:3647455 +667105 Gm8459 MGI:MGI:3647456 +667106 Gm13620 MGI:MGI:3650077 +667107 Gm8460 MGI:MGI:3646670 +667112 Gm8463 MGI:MGI:3644490 +667113 Gm8464 MGI:MGI:3645517 +667114 Gm8465 MGI:MGI:3644496 +667115 Gm15534 MGI:MGI:3704268 +667118 Zbed6 MGI:MGI:3828086|Ensembl:ENSMUSG00000094410|Ensembl:ENSMUSG00000102049|Vega:OTTMUSG00000049665|Vega:OTTMUSG00000049666 +667120 Gm8468 MGI:MGI:3647676 +667125 Csnk2a1-ps1 MGI:MGI:88544 +667126 Gm8472 MGI:MGI:3647670 +667127 Gm15847 MGI:MGI:3783237 +667128 Gm8473 MGI:MGI:3647680 +667129 Vmn1r103 MGI:MGI:3647681|Ensembl:ENSMUSG00000096663|Vega:OTTMUSG00000038196 +667130 Gm8475 MGI:MGI:3644679 +667135 Vmn1r104 MGI:MGI:3644682|Ensembl:ENSMUSG00000096903|Vega:OTTMUSG00000038197 +667138 Gm15779 MGI:MGI:3783221 +667141 Gm8479 MGI:MGI:3647865 +667143 Gm8480 MGI:MGI:3647867 +667147 Rpl7a-ps12 MGI:MGI:3647534 +667148 Gm8482 MGI:MGI:3647858 +667150 Gm11865 MGI:MGI:3650453 +667152 Gm8483 MGI:MGI:3644915 +667153 Gm8484 MGI:MGI:3648172 +667156 Gm8486 MGI:MGI:3644911 +667159 Gm8488 MGI:MGI:3644909 +667160 Gm15490 MGI:MGI:3782936 +667162 Gm8489 MGI:MGI:3648086 +667163 Gm12182 MGI:MGI:3650366 +667166 Vmn1r-ps71 MGI:MGI:3648089 +667167 Rpl31-ps22 MGI:MGI:3783213 +667170 Gm8492 MGI:MGI:3643249 +667171 Gm8493 MGI:MGI:3779800 +667172 Gm8494 MGI:MGI:3645114 +667174 Gm8495 MGI:MGI:3645109 +667175 Gm15727 MGI:MGI:3783170 +667177 Rpl36-ps11 MGI:MGI:3643239 +667178 Gm8497 MGI:MGI:3645117 +667180 Vmn2r20 MGI:MGI:3646439|Ensembl:ENSMUSG00000094145|Vega:OTTMUSG00000040017 +667181 Gm8498 MGI:MGI:3646440 +667182 Gm15785 MGI:MGI:3783227 +667186 Vmn1r-ps75 MGI:MGI:3646444 +667187 Gm8501 MGI:MGI:3646445 +667189 Gm8502 MGI:MGI:3646437 +667190 Gm8503 MGI:MGI:3646324 +667191 Gm8504 MGI:MGI:3643538 +667192 Gm13294 MGI:MGI:3649472 +667193 Gm8505 MGI:MGI:3643537 +667194 Gm8506 MGI:MGI:3643897 +667198 Gm8508 MGI:MGI:3643536 +667199 Vmn1r128 MGI:MGI:3643535|Ensembl:ENSMUSG00000095758|Vega:OTTMUSG00000038165 +667201 Gm8510 MGI:MGI:3648242 +667202 Rps2-ps3 MGI:MGI:3648241 +667203 Gm8512 MGI:MGI:3648240 +667204 Gm8513 MGI:MGI:3648246 +667205 Gm8514 MGI:MGI:3648245 +667207 Gm8515 MGI:MGI:3648243 +667209 Gm8517 MGI:MGI:3648238 +667210 Gm8518 MGI:MGI:3645036 +667211 Gm13296 MGI:MGI:3649473 +667212 Gm11848 MGI:MGI:3652231 +667213 Gm10416 MGI:MGI:3645037|Ensembl:ENSMUSG00000105044 +667214 9930111J21Rik1 MGI:MGI:3041173|Ensembl:ENSMUSG00000069893|Vega:OTTMUSG00000005529 +667215 Vmn1r125 MGI:MGI:3704112|Ensembl:ENSMUSG00000095309|Vega:OTTMUSG00000038162 +667216 Gm8520 MGI:MGI:3645038 +667217 Gm8521 MGI:MGI:3645039 +667218 Gm8522 MGI:MGI:3645035 +667219 Gm12186 MGI:MGI:3649200 +667221 Mup-ps3 MGI:MGI:3650796 +667226 Gm8524 MGI:MGI:3648452 +667227 Gm8525 MGI:MGI:3648451 +667230 Gm8526 MGI:MGI:3645225 +667233 Gm8529 MGI:MGI:3645224 +667234 Mup-ps9 MGI:MGI:3649622 +667237 Gm8531 MGI:MGI:3645221 +667238 Gm8532 MGI:MGI:3645219 +667239 Mup-ps10 MGI:MGI:3649623 +667240 Vmn1r121 MGI:MGI:3648662|Ensembl:ENSMUSG00000094680|Vega:OTTMUSG00000038158 +667241 Gm8534 MGI:MGI:3648661 +667242 Mup-ps11 MGI:MGI:3649621 +667243 Gm8535 MGI:MGI:3648660 +667244 Vmn2r-ps139 MGI:MGI:3761343 +667245 Rpl31-ps24 MGI:MGI:3648658 +667246 Gm8538 MGI:MGI:3648657 +667247 Gm13310 MGI:MGI:3650665 +667250 Gm12657 MGI:MGI:3651714 +667251 Gm11868 MGI:MGI:3650507 +667253 Gm8539 MGI:MGI:3779802 +667254 Gm8540 MGI:MGI:3645422 +667256 4921511M17Rik MGI:MGI:1925342|Ensembl:ENSMUSG00000094577|Vega:OTTMUSG00000019263 +667257 Gm8541 MGI:MGI:3645424 +667259 Vmn1r118 MGI:MGI:3645425|Ensembl:ENSMUSG00000094589|Vega:OTTMUSG00000038153 +667260 Gm8543 MGI:MGI:3648878 +667262 Vmn1r117 MGI:MGI:3648880|Ensembl:ENSMUSG00000096737|Vega:OTTMUSG00000038152 +667264 Gm8545 MGI:MGI:3648875 +667266 Gm8546 MGI:MGI:3647346 +667268 Vmn1r116 MGI:MGI:3648873|Ensembl:ENSMUSG00000095973|Vega:OTTMUSG00000038151 +667271 Olfr1458 MGI:MGI:3031292|Ensembl:ENSMUSG00000062844|Vega:OTTMUSG00000059469 +667273 Vmn1r115 MGI:MGI:3645605|Ensembl:ENSMUSG00000091435|Vega:OTTMUSG00000038150 +667276 Gm8550 MGI:MGI:3779803 +667277 C1rb MGI:MGI:3779804|Ensembl:ENSMUSG00000098470|Vega:OTTMUSG00000044915 +667278 Mup-ps16 MGI:MGI:3645603 +667279 Rps2-ps10 MGI:MGI:3645604 +667280 Hmgb1-ps8 MGI:MGI:96114 +667281 H60b MGI:MGI:3649078|Ensembl:ENSMUSG00000075297|Vega:OTTMUSG00000033465 +667284 Gm8556 MGI:MGI:3649082 +667286 Gm12189 MGI:MGI:3650668 +667287 Gm8557 MGI:MGI:3649080 +667291 Gm13578 MGI:MGI:3649303 +667292 Vmn1r111 MGI:MGI:3645811|Ensembl:ENSMUSG00000095768|Vega:OTTMUSG00000038146 +667295 Mup-ps18 MGI:MGI:3651979 +667296 Gm12947 MGI:MGI:3649527 +667299 Gm16531 MGI:MGI:4362088 +667300 Olfr1464-ps1 MGI:MGI:3031298 +667306 Gm11634 MGI:MGI:3650266 +667307 Gm8564 MGI:MGI:3644121 +667309 Gm8565 MGI:MGI:3644126 +667310 Gm8566 MGI:MGI:3647296 +667313 Gm8569 MGI:MGI:3647297 +667317 Gm8572 MGI:MGI:3647293 +667324 Gm8574 MGI:MGI:3643884 +667325 Gm8575 MGI:MGI:3643885 +667329 Gm13365 MGI:MGI:3651225 +667331 Gm8578 MGI:MGI:3647061 +667335 Gm8579 MGI:MGI:3647057|Ensembl:ENSMUSG00000106779 +667338 Gm8580 MGI:MGI:3647055 +667339 Gm8581 MGI:MGI:3647054 +667341 Gm8582 MGI:MGI:3643667 +667344 Gm8584 MGI:MGI:3643662 +667348 Gm8586 MGI:MGI:3643670 +667350 Gm8587 MGI:MGI:3646799 +667351 Gm8588 MGI:MGI:3646798 +667353 Gm8590 MGI:MGI:3646800 +667354 Gm12969 MGI:MGI:3650134 +667358 Vmn1r-ps76 MGI:MGI:3646795 +667359 Gpr31c MGI:MGI:1354371 +667360 Gm8594 MGI:MGI:3643421 +667369 Gm8595 MGI:MGI:3643427 +667370 Ifit3b MGI:MGI:3698419|Ensembl:ENSMUSG00000062488|Vega:OTTMUSG00000016648 +667371 Gm8596 MGI:MGI:3646555 +667372 Gm8597 MGI:MGI:3779808 +667373 Ifit1bl1 MGI:MGI:3650685|Ensembl:ENSMUSG00000079339|Vega:OTTMUSG00000016644 +667375 Gm8598 MGI:MGI:3646558 +667377 Gm8599 MGI:MGI:3646556 +667378 Gm8600 MGI:MGI:3646559 +667379 Spin2-ps2 MGI:MGI:3705652 +667380 Gm8601 MGI:MGI:3643183 +667381 Gm8602 MGI:MGI:3805954 +667382 Xlr3d-ps MGI:MGI:3574105 +667383 Gm650 MGI:MGI:2685496 +667384 Gm16050 MGI:MGI:3801837 +667385 Gm8604 MGI:MGI:3643186 +667387 Xlr4d-ps MGI:MGI:3574102 +667388 Gm8605 MGI:MGI:3643180 +667394 Gm8606 MGI:MGI:3646345 +667395 Gm8607 MGI:MGI:3646344 +667400 Gm8609 MGI:MGI:3648173 +667404 Vmn1r135 MGI:MGI:3648167|Ensembl:ENSMUSG00000095064|Vega:OTTMUSG00000038114 +667407 Gm8613 MGI:MGI:3648168 +667409 Gm8614 MGI:MGI:3644907 +667410 Gm8615 MGI:MGI:3647532 +667411 Gm8616 MGI:MGI:3647863 +667413 Gm8617 MGI:MGI:3647861 +667414 Gm8618 MGI:MGI:3647540 +667415 Phf2os1 MGI:MGI:3645592 +667421 Gm16443 MGI:MGI:3645113 +667422 Gm8623 MGI:MGI:3644689|Ensembl:ENSMUSG00000062458 +667423 Gm8624 MGI:MGI:3646811|Ensembl:ENSMUSG00000083705 +667425 Gm8625 MGI:MGI:3644686 +667431 Vmn1r-ps78 MGI:MGI:3647675 +667432 Gm8629 MGI:MGI:3646127 +667433 Gm8630 MGI:MGI:3647677 +667435 Igkv17-121 MGI:MGI:3647671|IMGT/GENE-DB:IGKV17-121 +667437 Xlr3e-ps MGI:MGI:3574183 +667438 Gm8633 MGI:MGI:3647678|Ensembl:ENSMUSG00000112896 +667440 Gm8634 MGI:MGI:3645518 +667441 Trav3-1 MGI:MGI:3644489|IMGT/GENE-DB:TRAV3-1 +667442 Gm15321 MGI:MGI:3782935 +667443 Gm13612 MGI:MGI:3651734 +667444 Vmn1r139 MGI:MGI:3644494|Ensembl:ENSMUSG00000074311|Vega:OTTMUSG00000038120 +667445 Gm8637 MGI:MGI:3645520 +667449 Trav6-1 MGI:MGI:3644497|IMGT/GENE-DB:TRAV6-1 +667451 Gm11214 MGI:MGI:3651045 +667456 Gm8641 MGI:MGI:3647459 +667458 Gm8642 MGI:MGI:3647457 +667459 Gm8643 MGI:MGI:3647458 +667460 Gm8644 MGI:MGI:3644260 +667464 Vmn1r142 MGI:MGI:3644264|Ensembl:ENSMUSG00000095273|Vega:OTTMUSG00000038123 +667465 Gm8648 MGI:MGI:3644263 +667466 Gm15454 MGI:MGI:3644262 +667468 Gm8649 MGI:MGI:3644257 +667469 Vmn1r143 MGI:MGI:3644289|Ensembl:ENSMUSG00000096071|Vega:OTTMUSG00000038124 +667471 Gm8652 MGI:MGI:3643616 +667472 Gm8653 MGI:MGI:3647206|Ensembl:ENSMUSG00000094981|Vega:OTTMUSG00000038125 +667475 Gm8655 MGI:MGI:3647209 +667476 Trav8d-1 MGI:MGI:3650121|IMGT/GENE-DB:TRAV8D-1 +667481 Trav6d-5 MGI:MGI:3649416|IMGT/GENE-DB:TRAV6D-5 +667483 Gm8659 MGI:MGI:3645697 +667484 Gm15711 MGI:MGI:3783153 +667485 Gm8660 MGI:MGI:3645692|Ensembl:ENSMUSG00000093917|Vega:OTTMUSG00000038055 +667486 Gm8661 MGI:MGI:3645695 +667487 Gm8662 MGI:MGI:3645694 +667488 Gm270 MGI:MGI:2685116 +667490 Gm8663 MGI:MGI:3648745 +667492 Gm8664 MGI:MGI:3648743 +667493 Gm13333 MGI:MGI:3649264 +667496 Gm8666 MGI:MGI:3648747 +667497 Gm8667 MGI:MGI:3648748 +667498 Gm8668 MGI:MGI:3648751 +667499 Gm11220 MGI:MGI:3651695 +667500 Gm8669 MGI:MGI:3643440 +667501 Gm8670 MGI:MGI:3643441 +667503 Gm8672 MGI:MGI:3643443 +667504 Vmn1r152 MGI:MGI:3643438|Ensembl:ENSMUSG00000095383|Vega:OTTMUSG00000038060 +667507 Gm8674 MGI:MGI:3645762 +667510 Gm8675 MGI:MGI:3646578|Ensembl:ENSMUSG00000106963 +667511 Gm8676 MGI:MGI:3646577 +667512 Gm8677 MGI:MGI:3646576|Ensembl:ENSMUSG00000094748|Vega:OTTMUSG00000038061 +667517 Gm8679 MGI:MGI:3646571 +667518 Gm8680 MGI:MGI:3646580 +667519 Gm8681 MGI:MGI:3646579 +667521 Gm13332 MGI:MGI:3649261 +667524 Gm8682 MGI:MGI:3643679 +667525 Rps19-ps2 MGI:MGI:3647073 +667526 Gm8684 MGI:MGI:3643677 +667527 Gm8685 MGI:MGI:3643678 +667528 Gm13641 MGI:MGI:3651867 +667529 Gm8686 MGI:MGI:3643672 +667530 Vmn1r155 MGI:MGI:3646821|Ensembl:ENSMUSG00000094905|Vega:OTTMUSG00000038063 +667531 Gm8688 MGI:MGI:3646820 +667532 Gm8689 MGI:MGI:3646823 +667534 Rps19-ps5 MGI:MGI:3646817 +667536 Vmn1r-ps80 MGI:MGI:3646819 +667537 Gm8692 MGI:MGI:3646818 +667541 LOC667541 MGI:MGI:3642967 +667542 Trav12d-3 MGI:MGI:3704434|IMGT/GENE-DB:TRAV12D-3 +667543 Gm8693 MGI:MGI:3642968|Ensembl:ENSMUSG00000095081|Vega:OTTMUSG00000038065 +667547 Trav13d-2 MGI:MGI:3643151|IMGT/GENE-DB:TRAV13D-2 +667548 Gm8696 MGI:MGI:3642963 +667549 Gm8697 MGI:MGI:3642964 +667550 Igkv10-94 MGI:MGI:3646140|IMGT/GENE-DB:IGKV10-94 +667551 Vmn1r157 MGI:MGI:3646139|Ensembl:ENSMUSG00000095619|Vega:OTTMUSG00000038066 +667552 Gm8700 MGI:MGI:3779809 +667555 Gm11581 MGI:MGI:3652083 +667556 Gm8701 MGI:MGI:3646142 +667558 Gm8702 MGI:MGI:3646137 +667560 Gm8703 MGI:MGI:3643205 +667562 Gm8704 MGI:MGI:3643203 +667563 Gm8705 MGI:MGI:3643204 +667564 Gm13347 MGI:MGI:3649701 +667565 Gm8706 MGI:MGI:3643202 +667566 Gm8707 MGI:MGI:3643201 +667567 Trav14-2 MGI:MGI:3649206|IMGT/GENE-DB:TRAV14-2 +667570 Gm8708 MGI:MGI:3646358 +667571 Gm14706 MGI:MGI:3646357 +667572 Gm8709 MGI:MGI:3646360|Ensembl:ENSMUSG00000098179 +667574 Trav9d-4 MGI:MGI:4889087|IMGT/GENE-DB:TRAV9D-4 +667580 Gm8711 MGI:MGI:3644351 +667582 Gm8712 MGI:MGI:3644353 +667583 Trav5d-4 MGI:MGI:3704130|IMGT/GENE-DB:TRAV5D-4 +667584 Gm8714 MGI:MGI:3644347 +667585 Gm8715 MGI:MGI:3644348 +667586 Vmn1r163 MGI:MGI:3644349|Ensembl:ENSMUSG00000094934|Vega:OTTMUSG00000038029 +667587 Gm8717 MGI:MGI:3644350 +667592 Gm11599 MGI:MGI:3651840 +667596 Trav13d-3 MGI:MGI:5293419|IMGT/GENE-DB:TRAV13D-3 +667597 BC023105 MGI:MGI:2384767 +667598 Gm8719 MGI:MGI:3647551 +667599 Gm8720 MGI:MGI:3647550|Ensembl:ENSMUSG00000096601|Vega:OTTMUSG00000038030 +667604 Trav8d-2 MGI:MGI:3647760|IMGT/GENE-DB:TRAV8D-2 +667606 Gm8722 MGI:MGI:3647758 +667607 Gm8723 MGI:MGI:3647757 +667609 Gm13328 MGI:MGI:3651185 +667610 Gm8724 MGI:MGI:3644570 +667611 Gm8725 MGI:MGI:3644571 +667612 Ncr3-ps MGI:MGI:2149332 +667616 Gm8728 MGI:MGI:3644568 +667617 Rps4x-ps MGI:MGI:3644569 +667618 Gm8730 MGI:MGI:3644565 +667619 Gm8731 MGI:MGI:3644566 +667621 Igkv4-77 MGI:MGI:3647937|IMGT/GENE-DB:IGKV4-77 +667623 Vmn1r-ps83 MGI:MGI:3647939 +667624 Gm8734 MGI:MGI:3647934 +667626 Trav10n MGI:MGI:3647936|IMGT/GENE-DB:TRAV10N +667630 Gm8737 MGI:MGI:3644777 +667631 Gm8738 MGI:MGI:3644778 +667632 Gm8739 MGI:MGI:3644775 +667635 Trav7n-5 MGI:MGI:3644782|IMGT/GENE-DB:TRAV7N-5 +667636 Gm8741 MGI:MGI:3644779 +667637 Gm8742 MGI:MGI:3644780 +667638 Gm11231 MGI:MGI:3650253 +667639 Olfr621-ps1 MGI:MGI:3030455 +667644 Gm11605 MGI:MGI:3651339 +667650 Gm8744 MGI:MGI:3644116 +667651 Gm8745 MGI:MGI:3644117 +667655 Gm8747 MGI:MGI:3643417 +667656 Gm8748 MGI:MGI:3644122 +667658 Gm8749 MGI:MGI:3644124 +667659 Gm12209 MGI:MGI:3650470 +667660 Trav9n-2 MGI:MGI:3704438|IMGT/GENE-DB:TRAV9N-2 +667662 Gm8750 MGI:MGI:3647542 +667663 Myo3a MGI:MGI:2183924|Ensembl:ENSMUSG00000025716 +667666 Zfp600 MGI:MGI:3705222|Ensembl:ENSMUSG00000066007|Vega:OTTMUSG00000010694 +667669 Gm8752 MGI:MGI:3647539 +667670 Igkv4-65 MGI:MGI:3644339|IMGT/GENE-DB:IGKV4-65 +667672 Gm8754 MGI:MGI:3644783 +667675 Gm8755 MGI:MGI:3644336 +667676 Gm8756 MGI:MGI:3644333 +667678 Gm15750 MGI:MGI:3783192 +667679 Gm8757 MGI:MGI:3644342 +667681 Trav12n-3 MGI:MGI:3704131|IMGT/GENE-DB:TRAV12N-3 +667682 Rpl31-ps8 MGI:MGI:3647726 +667683 Igkv4-59 MGI:MGI:3646808|IMGT/GENE-DB:IGKV4-59 +667684 Gm8761 MGI:MGI:3646807 +667686 Mif-ps1 MGI:MGI:103175 +667688 Rpl17-ps2 MGI:MGI:3815013 +667691 Gm14747 MGI:MGI:3643665 +667692 Gm8764 MGI:MGI:3643666|Ensembl:ENSMUSG00000097878|Vega:OTTMUSG00000042980 +667693 Gm8765 MGI:MGI:3704126|Ensembl:ENSMUSG00000094918|Vega:OTTMUSG00000046881 +667696 Gm8767 MGI:MGI:3647013 +667697 Gm8768 MGI:MGI:3643663 +667700 Gm8770 MGI:MGI:3646216 +667705 Gm8773 MGI:MGI:3646213|Ensembl:ENSMUSG00000073234|Vega:OTTMUSG00000048790 +667706 Gm8774 MGI:MGI:3646210 +667711 Gm8776 MGI:MGI:3643285 +667712 Gm8777 MGI:MGI:3643286 +667713 Gm11251 MGI:MGI:3651054 +667715 Gm8778 MGI:MGI:3779812 +667716 Gm11789 MGI:MGI:3650495 +667717 Gm8779 MGI:MGI:3643288 +667718 Gm21976 MGI:MGI:5439445 +667721 Gm8782 MGI:MGI:3642977 +667722 Gm11485 MGI:MGI:3705569 +667723 Gm8783 MGI:MGI:3646027 +667727 Gm8784 MGI:MGI:3646031 +667728 Hist1h2al MGI:MGI:3646032 +667729 Gm13668 MGI:MGI:3650878 +667731 Rps2-ps4 MGI:MGI:3651115 +667732 Gm8785 MGI:MGI:3643687 +667735 Gm15529 MGI:MGI:3782977 +667736 Gm8787 MGI:MGI:3643055|Ensembl:ENSMUSG00000073077 +667737 Gm11652 MGI:MGI:3651204 +667739 Rps6-ps4 MGI:MGI:3650907 +667742 Piezo2 MGI:MGI:1918781|Ensembl:ENSMUSG00000041482|Vega:OTTMUSG00000028308 +667743 Gm8789 MGI:MGI:3646651 +667745 Gm8790 MGI:MGI:3646655 +667746 Gm8791 MGI:MGI:3646653 +667749 Gm8792 MGI:MGI:3646656 +667752 Gm8793 MGI:MGI:3643768 +667754 Ces2d-ps MGI:MGI:3704319 +667756 Gm8795 MGI:MGI:3643764 +667758 Gm8796 MGI:MGI:3643770 +667759 Gm8797 MGI:MGI:3643769 +667760 Gm8798 MGI:MGI:3646429 +667762 Gm12218 MGI:MGI:3649336 +667764 Gm15854 MGI:MGI:3783238 +667765 Trav10 MGI:MGI:3704132|IMGT/GENE-DB:TRAV10 +667766 Gm8801 MGI:MGI:3779813 +667767 Gm8802 MGI:MGI:3647981 +667768 Gm11240 MGI:MGI:3651058|Ensembl:ENSMUSG00000085034 +667772 Myh15 MGI:MGI:3643515|Ensembl:ENSMUSG00000092009 +667774 Gm8804 MGI:MGI:3643513 +667775 Gm8805 MGI:MGI:3643512 +667776 Gm8806 MGI:MGI:3643511 +667777 Gm8807 MGI:MGI:3643510 +667778 Gm11771 MGI:MGI:3652201 +667779 Rpl30-ps8 MGI:MGI:3643509 +667780 Gm13871 MGI:MGI:3702126|Ensembl:ENSMUSG00000096333|Vega:OTTMUSG00000014862 +667781 Gm8809 MGI:MGI:3645410 +667782 Gm8810 MGI:MGI:3779814 +667786 Gm8812 MGI:MGI:3643091 +667788 Gm8813 MGI:MGI:3645282 +667791 Gm8814 MGI:MGI:3648632 +667792 Gm8815 MGI:MGI:3648635 +667793 Gm8816 MGI:MGI:3648634 +667794 Gm8817 MGI:MGI:3648637 +667795 Gm8818 MGI:MGI:3645903 +667797 Gm8820 MGI:MGI:3648638 +667799 Gm8822 MGI:MGI:3648640 +667801 Gm8823 MGI:MGI:3647094 +667802 Gm8824 MGI:MGI:3647096 +667803 H2-T-ps MGI:MGI:2442805 +667804 Gm14424 MGI:MGI:3650516 +667806 Gm8825 MGI:MGI:3647098 +667807 Gm8826 MGI:MGI:3647097 +667809 Gm8827 MGI:MGI:3647099 +667812 Gm8828 MGI:MGI:3643936 +667817 Gm14427 MGI:MGI:3652026 +667822 Gm8832 MGI:MGI:3646854 +667823 Trim5 MGI:MGI:3646853|Ensembl:ENSMUSG00000060441|Vega:OTTMUSG00000019190 +667824 Gm8834 MGI:MGI:3646859 +667825 Gm14772 MGI:MGI:3646858 +667826 Gm12230 MGI:MGI:3649746 +667827 Gm8835 MGI:MGI:3646857 +667828 Gm13655 MGI:MGI:3650029 +667829 Gm8836 MGI:MGI:3646852 +667830 Gm8837 MGI:MGI:3643713 +667832 Gm12231 MGI:MGI:3651344 +667837 Gm8838 MGI:MGI:3643717 +667838 Naip3 MGI:MGI:1298225 +667840 Amd-ps5 MGI:MGI:3647577 +667841 Gm8839 MGI:MGI:3647576 +667842 Gm8840 MGI:MGI:3647579 +667845 Gm11241 MGI:MGI:3652121 +667849 Gm8843 MGI:MGI:3647571 +667852 Gm8844 MGI:MGI:3644372 +667858 Gm11243 MGI:MGI:3652116 +667859 Igkv8-18 MGI:MGI:1330845|IMGT/GENE-DB:IGKV8-18 +667861 Gm8847 MGI:MGI:3647328 +667862 Gm11245 MGI:MGI:3651884 +667863 Gm8848 MGI:MGI:3647327 +667864 Gm8849 MGI:MGI:3647326 +667865 Igkv6-17 MGI:MGI:1330833|IMGT/GENE-DB:IGKV6-17 +667867 Gm8850 MGI:MGI:3647325 +667872 Gm8853 MGI:MGI:3644164 +667876 Gm8855 MGI:MGI:3644160 +667877 Gm8856 MGI:MGI:3644161 +667878 Gm12242 MGI:MGI:3649717 +667879 Gm12587 MGI:MGI:3649689 +667880 Gm8857 MGI:MGI:3648006 +667881 Igkv6-14 MGI:MGI:1330830|IMGT/GENE-DB:IGKV6-14 +667882 Usp17le-ps MGI:MGI:3582591 +667883 Gm8858 MGI:MGI:3648007 +667884 Gm8859 MGI:MGI:3648009 +667886 Gm8860 MGI:MGI:3648010 +667888 Gm8861 MGI:MGI:3648005 +667889 Gm8862 MGI:MGI:3648004 +667890 Gm8863 MGI:MGI:3644829 +667891 Gm8864 MGI:MGI:3644830 +667892 Gm12266 MGI:MGI:3650880 +667893 Gm8865 MGI:MGI:3647567 +667894 Gm8866 MGI:MGI:3644827 +667896 Gm8868 MGI:MGI:3644825 +667897 Gm8869 MGI:MGI:3644826 +667899 Igkv6-13 MGI:MGI:1330829|IMGT/GENE-DB:IGKV6-13 +667900 Gm8870 MGI:MGI:3645634 +667901 Gm8871 MGI:MGI:3645635 +667902 Gm8872 MGI:MGI:3645636 +667903 Gm14794 MGI:MGI:3645637 +667904 Gm8873 MGI:MGI:3645638 +667906 Gm13649 MGI:MGI:3649521 +667907 Gm8874 MGI:MGI:3645640 +667908 Igkv3-12-1 MGI:MGI:3645632|IMGT/GENE-DB:IGKV3-12-1 +667911 Gm8876 MGI:MGI:3648903 +667912 Gm8877 MGI:MGI:3648902 +667914 Igkv3-12 MGI:MGI:1330815|IMGT/GENE-DB:IGKV3-12 +667915 Gm8878 MGI:MGI:3648906 +667916 Gm8879 MGI:MGI:3648905 +667917 Igkv3-11 MGI:MGI:1330820|IMGT/GENE-DB:IGKV3-11 +667918 Olfr664 MGI:MGI:3030498 +667919 Gm8880 MGI:MGI:3648900 +667920 Gm13726 MGI:MGI:3649259 +667922 Gm11263 MGI:MGI:3651899 +667924 Igkv3-10 MGI:MGI:1330821|IMGT/GENE-DB:IGKV3-10 +667927 Gm8881 MGI:MGI:3645849 +667928 Igkv3-9 MGI:MGI:1330856|IMGT/GENE-DB:IGKV3-9 +667929 Gm8882 MGI:MGI:3645847|Ensembl:ENSMUSG00000030143|Vega:OTTMUSG00000034589 +667931 Gm8883 MGI:MGI:3649116|Ensembl:ENSMUSG00000099707 +667933 Gm8884 MGI:MGI:3649118 +667936 Igkv3-6 MGI:MGI:1330853|IMGT/GENE-DB:IGKV3-6 +667937 Gm8885 MGI:MGI:3649121 +667939 Gm8887 MGI:MGI:3649122 +667940 Igkv3-5 MGI:MGI:1330854|IMGT/GENE-DB:IGKV3-5 +667941 Gm8888 MGI:MGI:3646062 +667946 Igkv3-3 MGI:MGI:1330849|IMGT/GENE-DB:IGKV3-3 +667947 Gm12247 MGI:MGI:3649489 +667948 Gm8890 MGI:MGI:3779817 +667949 Gm8891 MGI:MGI:3646065 +667951 Gm8893 MGI:MGI:3779818 +667952 Gm8894 MGI:MGI:3643084 +667954 Gm8895 MGI:MGI:3643891 +667956 Gm8896 MGI:MGI:3643082 +667957 Cyp2b27-ps MGI:MGI:3643081 +667961 Gm8897 MGI:MGI:3779819|Ensembl:ENSMUSG00000096732|Vega:OTTMUSG00000036524 +667962 Zfp966 MGI:MGI:3709288|Ensembl:ENSMUSG00000089756|Vega:OTTMUSG00000016203 +667964 Gm8899 MGI:MGI:3646245 +667966 Gm8900 MGI:MGI:3646243 +667968 Gm8902 MGI:MGI:3646241 +667974 Gm8906 MGI:MGI:3779820 +667975 Gm8907 MGI:MGI:3643311 +667976 Gm8908 MGI:MGI:3643312 +667977 Gm8909 MGI:MGI:3704134|Ensembl:ENSMUSG00000073402|Vega:OTTMUSG00000037026 +667978 Gm8910 MGI:MGI:3643310 +667982 Gm8911 MGI:MGI:3646459 +667985 Gm11185 MGI:MGI:3650877 +667987 Gm8913 MGI:MGI:3646463 +667988 Gm8914 MGI:MGI:3646464 +667992 Tas2r103 MGI:MGI:1890257|Ensembl:ENSMUSG00000030196|Vega:OTTMUSG00000056973 +667993 Gm8916 MGI:MGI:3643555 +667994 Gm8917 MGI:MGI:3643560 +667997 Gm8918 MGI:MGI:3643558 +667999 Gm8919 MGI:MGI:3643562 +668001 Gm8920 MGI:MGI:3643680 +668002 Gm8921 MGI:MGI:3646108 +668005 Gm13674 MGI:MGI:3651408 +668008 Gm8922 MGI:MGI:3779821|Ensembl:ENSMUSG00000094105|Vega:OTTMUSG00000036527 +668010 Gm12416 MGI:MGI:3650588 +668011 Gm8924 MGI:MGI:3643161 +668015 Gm8925 MGI:MGI:3643158 +668017 Gm8926 MGI:MGI:3779823|Ensembl:ENSMUSG00000094205|Vega:OTTMUSG00000036528 +668018 Gm8927 MGI:MGI:3643156 +668021 Gm8929 MGI:MGI:3646328 +668022 Gm8930 MGI:MGI:3646325 +668026 Gm8932 MGI:MGI:3646329 +668027 Gm13700 MGI:MGI:3651955 +668030 Gm14432 MGI:MGI:3702415 +668032 Gm8934 MGI:MGI:3643402 +668033 Gm8935 MGI:MGI:3643401 +668034 Rpl19-ps9 MGI:MGI:3643398 +668035 Olfr687 MGI:MGI:3030521 +668036 Gm8938 MGI:MGI:3643400 +668037 Gm8939 MGI:MGI:3643399 +668038 Gm8940 MGI:MGI:3643403 +668039 Gm14434 MGI:MGI:3702417|Ensembl:ENSMUSG00000078881|Vega:OTTMUSG00000016611 +668040 Gm8941 MGI:MGI:3779824 +668041 Gm8942 MGI:MGI:3645705 +668042 Gm8943 MGI:MGI:3645706 +668044 Gm8945 MGI:MGI:3645708 +668045 Pgam1-ps2 MGI:MGI:3645709 +668047 Rnf170-ps MGI:MGI:3645710 +668050 Gm8947 MGI:MGI:3648958 +668051 Gm8948 MGI:MGI:3648957 +668052 Gm8949 MGI:MGI:3779825 +668053 Gm8950 MGI:MGI:3648955 +668057 Gm8952 MGI:MGI:3648959 +668058 Gm12570 MGI:MGI:3652277 +668059 Gm8953 MGI:MGI:3648962 +668062 Gm8955 MGI:MGI:3645918 +668063 Gm8956 MGI:MGI:3645919 +668066 Gm14418 MGI:MGI:3702408 +668068 Gm8957 MGI:MGI:3779827 +668070 Gm8959 MGI:MGI:3642930 +668071 Gm8960 MGI:MGI:3642929 +668072 Gm8961 MGI:MGI:3642932 +668074 Gm8963 MGI:MGI:3642934 +668076 Gm8964 MGI:MGI:3642935 +668077 Gm13683 MGI:MGI:3650118 +668085 Gm8968 MGI:MGI:3644677 +668087 Gm8969 MGI:MGI:3645290 +668089 Gm8970 MGI:MGI:3645294 +668090 Gm8971 MGI:MGI:3648536 +668092 Gm8973 MGI:MGI:3648534 +668094 Gm8974 MGI:MGI:3648532 +668095 Lipo5 MGI:MGI:3648531 +668096 Gm13698 MGI:MGI:3702072 +668097 Gm8976 MGI:MGI:3648530 +668100 Gm13693 MGI:MGI:3702055 +668101 Sirpb1b MGI:MGI:3779828|Ensembl:ENSMUSG00000095028|Vega:OTTMUSG00000052298 +668103 Supt20-ps MGI:MGI:3645971 +668106 Gm8978 MGI:MGI:3647649 +668107 Gm13696 MGI:MGI:3702068 +668108 Gm8979 MGI:MGI:3703149 +668110 Syce1l MGI:MGI:1922247|Ensembl:ENSMUSG00000033409|Vega:OTTMUSG00000061747 +668112 Gm8980 MGI:MGI:3644463 +668113 Gm13694 MGI:MGI:3702064 +668115 Gm13697 MGI:MGI:3702070 +668117 Gm8982 MGI:MGI:3644465 +668118 Gm8983 MGI:MGI:3644468 +668119 Gm13691 MGI:MGI:3702053 +668121 Gm8984 MGI:MGI:3647416 +668124 Gm8986 MGI:MGI:3644764 +668126 Gm8987 MGI:MGI:3647411 +668127 Gm8988 MGI:MGI:3647410 +668128 Gm8989 MGI:MGI:3704114 +668129 Gm8990 MGI:MGI:3647409 +668131 Gm8991 MGI:MGI:3644227 +668132 Gm8992 MGI:MGI:3644228 +668136 Gm8993 MGI:MGI:3644225 +668137 Gm8994 MGI:MGI:3644226|Ensembl:ENSMUSG00000094973|Vega:OTTMUSG00000057216 +668139 Gm8995 MGI:MGI:3644223 +668140 Gm8996 MGI:MGI:3647165 +668143 Gm8999 MGI:MGI:3647166 +668144 Rps3a3 MGI:MGI:3643406 +668145 Gm9001 MGI:MGI:3647168 +668146 Gm9002 MGI:MGI:3647170 +668147 Gm13284 MGI:MGI:3701980 +668148 Gm9003 MGI:MGI:3647163 +668149 Gm9004 MGI:MGI:3647162 +668150 Gm9005 MGI:MGI:3644003 +668151 Gm9006 MGI:MGI:3644004 +668153 Gm9007 MGI:MGI:3644002 +668155 Gm9008 MGI:MGI:3644000 +668156 Gm9009 MGI:MGI:3643998 +668157 Gm12261 MGI:MGI:3650914 +668158 Ccdc85c MGI:MGI:3644008|Ensembl:ENSMUSG00000084883 +668160 Gm9012 MGI:MGI:3646932 +668162 Gm9013 MGI:MGI:3646930 +668166 Zxdb MGI:MGI:3694898|Ensembl:ENSMUSG00000073062|Vega:OTTMUSG00000018137 +668168 Gm9017 MGI:MGI:3646937 +668171 Zxda MGI:MGI:1921689 +668173 Pex10 MGI:MGI:2684988|Ensembl:ENSMUSG00000029047|Vega:OTTMUSG00000010596 +668177 Gm9022 MGI:MGI:3643783 +668178 Mettl7a3 MGI:MGI:3710670|Ensembl:ENSMUSG00000058057 +668179 Gm9023 MGI:MGI:3643784 +668181 Ncf2-rs MGI:MGI:97285 +668182 Rpl13-ps3 MGI:MGI:3646682 +668183 Gm9027 MGI:MGI:3646681 +668184 Gm9028 MGI:MGI:3646676 +668186 Gm9029 MGI:MGI:3646678 +668187 Gm9030 MGI:MGI:3646677 +668190 Rpl26-ps1 MGI:MGI:3643528 +668192 Gm9034 MGI:MGI:3643526 +668193 Gm9035 MGI:MGI:3643527 +668196 Gm9038 MGI:MGI:3643530 +668197 Gm9039 MGI:MGI:3643531 +668198 Gm9040 MGI:MGI:3643524 +668200 Esp15 MGI:MGI:3647149|Ensembl:ENSMUSG00000095104 +668201 Gm9042 MGI:MGI:3647150 +668202 Gm9043 MGI:MGI:3647147 +668203 Gm9044 MGI:MGI:3647148 +668205 Gm9045 MGI:MGI:3647146 +668206 Gm12617 MGI:MGI:3649880 +668208 Gm13288 MGI:MGI:3701985|Ensembl:ENSMUSG00000070908|Vega:OTTMUSG00000011289 +668209 Gm9046 MGI:MGI:3647143 +668210 Gm9047 MGI:MGI:3644212|Ensembl:ENSMUSG00000090685|Vega:OTTMUSG00000035854 +668212 Efr3b MGI:MGI:2444851|Ensembl:ENSMUSG00000020658 +668213 Gm9048 MGI:MGI:3644213 +668215 Hectd2os MGI:MGI:1919243|Ensembl:ENSMUSG00000087579 +668216 Gm9049 MGI:MGI:3644216 +668217 Gm9050 MGI:MGI:3644215 +668218 Bin2 MGI:MGI:3611448|Ensembl:ENSMUSG00000098112|Vega:OTTMUSG00000043210 +668221 Gm9051 MGI:MGI:3646915 +668222 Gm9052 MGI:MGI:3646916 +668224 Gm9054 MGI:MGI:3646918 +668225 Fignl2 MGI:MGI:3646919|Ensembl:ENSMUSG00000095440|Vega:OTTMUSG00000063171 +668228 Gm12269 MGI:MGI:3650595 +668230 Gm9056 MGI:MGI:3643992 +668232 Gm9057 MGI:MGI:3643991 +668233 Gm9058 MGI:MGI:3643990 +668234 Gm14803 MGI:MGI:3705495 +668236 Gm9059 MGI:MGI:3648922 +668238 Gm9060 MGI:MGI:3643989 +668239 Rps13-ps5 MGI:MGI:3650602 +668242 Gm9061 MGI:MGI:3647637 +668244 Gm9062 MGI:MGI:3647643 +668245 Gm9063 MGI:MGI:3647644 +668246 Gm9064 MGI:MGI:3647641 +668248 Gm9066 MGI:MGI:3647635 +668251 Gm9067 MGI:MGI:3644658 +668252 Gm9068 MGI:MGI:3644660 +668253 Dleu2 MGI:MGI:1934030|Ensembl:ENSMUSG00000097589 +668255 Rps11-ps2 MGI:MGI:3651796 +668257 Dgat2l6 MGI:MGI:3045268|Ensembl:ENSMUSG00000067597|Vega:OTTMUSG00000018289 +668260 Gm9071 MGI:MGI:3647400 +668262 Gm9072 MGI:MGI:3647402 +668267 Gm9075 MGI:MGI:3644696 +668270 Gm9077 MGI:MGI:3644458 +668271 Gm9078 MGI:MGI:3644457 +668272 Gm9079 MGI:MGI:3826365 +668275 Gm9081 MGI:MGI:3644454 +668277 Gm9083 MGI:MGI:3644452 +668283 Gm9085 MGI:MGI:3648061 +668286 Gm9086 MGI:MGI:3648056 +668289 Gm9088 MGI:MGI:3648064 +668291 Marcksl1-ps5 MGI:MGI:97148 +668294 Rps19-ps10 MGI:MGI:3645086 +668300 Rplp0-ps1 MGI:MGI:3648599 +668302 Gm9095 MGI:MGI:3648597 +668303 Kif26a MGI:MGI:2447072|Ensembl:ENSMUSG00000021294|Vega:OTTMUSG00000033713 +668306 LOC668306 - +668308 Gm9097 MGI:MGI:3648601 +668309 Gm9098 MGI:MGI:3648600 +668310 Cc2d2b MGI:MGI:3645359 +668311 Gm9099 MGI:MGI:3645360 +668317 Gm9102 MGI:MGI:3645358 +668318 Gm9103 MGI:MGI:3645364 +668319 Gm9104 MGI:MGI:3645365 +668320 Gm9105 MGI:MGI:3648833 +668321 Marcksl1-ps3 MGI:MGI:97146 +668323 Gm12297 MGI:MGI:3649682 +668325 Gm9107 MGI:MGI:3779835 +668327 Gm9108 MGI:MGI:3648830 +668331 Gm9109 MGI:MGI:3646301 +668332 Gm9110 MGI:MGI:3643561 +668336 Gm9111 MGI:MGI:3779836 +668339 Gm9112 MGI:MGI:3645559|Ensembl:ENSMUSG00000079479|Vega:OTTMUSG00000018170 +668341 Gm9113 MGI:MGI:3648183 +668342 Gm9114 MGI:MGI:3647353 +668343 Gm9115 MGI:MGI:3648181 +668344 Gm9116 MGI:MGI:3648187 +668346 Gm9117 MGI:MGI:3704095 +668347 Gm9118 MGI:MGI:3648185 +668349 Gm9119 MGI:MGI:3648179 +668351 Gm9120 MGI:MGI:3644974 +668353 Gm9121 MGI:MGI:3644976 +668354 Rps12-ps5 MGI:MGI:3644977 +668356 Gm9124 MGI:MGI:3644979 +668357 Dmrtc1c2 MGI:MGI:3802967|Ensembl:ENSMUSG00000067561|Vega:OTTMUSG00000018167 +668359 Gm9125 MGI:MGI:3702970|Ensembl:ENSMUSG00000094328|Vega:OTTMUSG00000042889 +668360 Gm9126 MGI:MGI:3648387 +668361 Gm9127 MGI:MGI:3648386 +668363 Gm9129 MGI:MGI:3648388 +668366 Gm9130 MGI:MGI:3648393 +668367 Gm9131 MGI:MGI:3648392 +668368 Gm9132 MGI:MGI:3648395 +668369 Gm9133 MGI:MGI:3648394 +668370 Gm9134 MGI:MGI:3645181 +668371 Gm9135 MGI:MGI:3645182 +668375 Gm9136 MGI:MGI:3645180 +668377 Gm9137 MGI:MGI:3645179 +668379 Scgb2b12 MGI:MGI:3645177|Ensembl:ENSMUSG00000097982|Vega:OTTMUSG00000043619 +668380 Gm9139 MGI:MGI:3645742 +668381 Scgb1b12 MGI:MGI:3645736|Ensembl:ENSMUSG00000101520|Vega:OTTMUSG00000045760 +668382 Pabpc1l2b-ps MGI:MGI:3644774 +668385 Gm9141 MGI:MGI:3643267 +668386 Gm9142 MGI:MGI:3644769 +668387 Gm9143 MGI:MGI:3643265 +668388 Gm9144 MGI:MGI:3643264 +668389 Ighv2-4 MGI:MGI:3643263|IMGT/GENE-DB:IGHV2-4 +668393 Gm9146 MGI:MGI:3646192 +668395 Ighv5-12 MGI:MGI:4439516|IMGT/GENE-DB:IGHV5-12 +668397 Gm9148 MGI:MGI:3646188 +668398 Gm9149 MGI:MGI:3646183 +668402 Gm13733 MGI:MGI:3650013 +668405 Rpl26-ps3 MGI:MGI:3646603 +668408 1700084K02Rik MGI:MGI:1920770 +668409 Rpl31-ps11 MGI:MGI:3646595 +668411 Gm9156 MGI:MGI:3647266 +668412 Gm9157 MGI:MGI:3643722 +668413 Gm9158 MGI:MGI:3643721 +668415 Gm9159 MGI:MGI:3647271 +668419 Scgb2b33 MGI:MGI:3643719 +668421 Ighv14-2 MGI:MGI:4439607|IMGT/GENE-DB:IGHV14-2 +668422 Gm9162 MGI:MGI:3646870 +668423 Ighv4-2 MGI:MGI:5009840|IMGT/GENE-DB:IGHV4-2 +668424 Gm13729 MGI:MGI:3649730 +668426 Gm9164 MGI:MGI:3646866 +668429 Gm9165 MGI:MGI:3647914 +668430 Gm9166 MGI:MGI:3648553 +668431 Gm9167 MGI:MGI:3643941 +668432 Gm1826 MGI:MGI:3037684 +668433 4930544D05Rik MGI:MGI:2148639|Ensembl:ENSMUSG00000087279|Vega:OTTMUSG00000006055 +668434 Gm9168 MGI:MGI:3648558 +668435 Pgk1-rs7 MGI:MGI:97562 +668436 Gm9169 MGI:MGI:3648561 +668438 Ighv3-3 MGI:MGI:3643949|IMGT/GENE-DB:IGHV3-3 +668439 Gm13738 MGI:MGI:3649860 +668440 Rpl23a-ps12 MGI:MGI:3649973 +668442 Gm12310 MGI:MGI:3650025 +668443 Gm9171 MGI:MGI:3647106 +668444 Gm9172 MGI:MGI:3647102 +668445 Gm13744 MGI:MGI:3650801 +668447 Gm13743 MGI:MGI:3650802 +668448 Gm9173 MGI:MGI:3647108 +668450 Gm9174 MGI:MGI:3643688 +668452 Gm15602 MGI:MGI:3783049 +668453 Gm9176 MGI:MGI:3644170 +668455 Mrto4-ps1 MGI:MGI:3644169 +668456 Gm9179 MGI:MGI:3644168 +668457 Rps10-ps1 MGI:MGI:3644167 +668458 Rab9b-ps1 MGI:MGI:3644175 +668459 Gm9182 MGI:MGI:3644174 +668460 Gm12780 MGI:MGI:3649896 +668461 Rpl23a-ps2 MGI:MGI:3651561 +668463 Kpna2-ps MGI:MGI:3647335 +668466 Gm12312 MGI:MGI:3649321 +668468 B230354O11Rik MGI:MGI:3647332 +668469 Ighv1-5 MGI:MGI:3704121|IMGT/GENE-DB:IGHV1-5 +668472 Rpl19-ps10 MGI:MGI:3644393 +668474 Ighv1-7 MGI:MGI:3704122|IMGT/GENE-DB:IGHV1-7 +668475 Gm9191 MGI:MGI:3644386 +668477 Gm9192 MGI:MGI:3644388 +668478 Ighv1-9 MGI:MGI:4439621|IMGT/GENE-DB:IGHV1-9 +668481 Gm9194 MGI:MGI:3647585 +668482 Gm9195 MGI:MGI:3779838 +668485 Gm9197 MGI:MGI:3647588 +668486 Gm14388 MGI:MGI:3650926 +668487 Gm9198 MGI:MGI:3647590 +668489 Gm9199 MGI:MGI:3647592 +668490 Gm9200 MGI:MGI:3779839 +668493 Ighv1-19-1 MGI:MGI:3644603|IMGT/GENE-DB:IGHV1-19-1 +668494 Gm9204 MGI:MGI:3644610 +668497 Ighv1-20 MGI:MGI:3644607|IMGT/GENE-DB:IGHV1-20 +668499 Ighv1-21 MGI:MGI:5009841|IMGT/GENE-DB:IGHV1-21 +668500 Gm9207 MGI:MGI:3779840 +668501 Zfp507 MGI:MGI:1916378|Ensembl:ENSMUSG00000044452|Vega:OTTMUSG00000029463 +668502 Gm9208 MGI:MGI:3648125 +668504 Gm9209 MGI:MGI:3645745 +668506 Gm9210 MGI:MGI:3648129 +668507 Gm9211 MGI:MGI:3648971 +668508 Gm9212 MGI:MGI:3648974 +668510 Ighv1-28 MGI:MGI:3644938|IMGT/GENE-DB:IGHV1-28 +668511 Ighv1-30 MGI:MGI:4937173|IMGT/GENE-DB:IGHV1-30 +668512 Gm9214 MGI:MGI:3644936 +668513 Tpt1-ps7 MGI:MGI:3779841 +668515 Ighv1-35 MGI:MGI:3644935|IMGT/GENE-DB:IGHV1-35 +668516 Gm9218 MGI:MGI:3644933 +668517 Ighv1-37 MGI:MGI:4439640|IMGT/GENE-DB:IGHV1-37 +668519 Gm9220 MGI:MGI:3648318 +668521 Ighv1-44 MGI:MGI:5009842|IMGT/GENE-DB:IGHV1-44 +668522 Ighv1-46 MGI:MGI:5009843|IMGT/GENE-DB:IGHV1-46 +668523 Mark4-ps MGI:MGI:3647884 +668525 Gm9222 MGI:MGI:3647701 +668526 Scgb2b17 MGI:MGI:3647697|Ensembl:ENSMUSG00000098094|Vega:OTTMUSG00000043621 +668528 Gm13758 MGI:MGI:3652137 +668529 Gm9224 MGI:MGI:3647881 +668530 Gm9225 MGI:MGI:3643031 +668531 Gm9226 MGI:MGI:3644713 +668534 Gm9227 MGI:MGI:3646995 +668536 Rpl31-ps18 MGI:MGI:3644718 +668539 Gm9229 MGI:MGI:3644708 +668540 Gm9230 MGI:MGI:3648549 +668541 Gm9231 MGI:MGI:3648548 +668542 Ighv1-62 MGI:MGI:5009844|IMGT/GENE-DB:IGHV1-62 +668543 Gm12400 MGI:MGI:3651916 +668544 Ighv1-62-1 MGI:MGI:3704125|IMGT/GENE-DB:IGHV1-62-1 +668548 Gm9234 MGI:MGI:3648545 +668549 Ighv1-62-3 MGI:MGI:3648544|IMGT/GENE-DB:IGHV1-63-1 +668552 Gm9236 MGI:MGI:3645301 +668553 Gm9237 MGI:MGI:3645302 +668554 Gm9238 MGI:MGI:3645306 +668555 Gm9239 MGI:MGI:3644761 +668556 Gm9240 MGI:MGI:3645305 +668557 Gm12441 MGI:MGI:3649265 +668558 Gm9241 MGI:MGI:3645299 +668559 Gm9242 MGI:MGI:3645172 +668560 Gm9243 MGI:MGI:3648329 +668561 Gm9244 MGI:MGI:3648328 +668563 Gm9245 MGI:MGI:3648326 +668565 Gm9246 MGI:MGI:3648324 +668566 Gm9247 MGI:MGI:3648323 +668567 Gm12331 MGI:MGI:3650004 +668568 Gm9248 MGI:MGI:3648332 +668570 Gm9249 MGI:MGI:3645132 +668572 2610021A01Rik MGI:MGI:1922662|Ensembl:ENSMUSG00000091474|Vega:OTTMUSG00000035884 +668575 Gm9251 MGI:MGI:3645129 +668576 Gm9252 MGI:MGI:3645130 +668577 Ighv1-73 MGI:MGI:3645131|IMGT/GENE-DB:IGHV1-73 +668578 Gm12486 MGI:MGI:3650949 +668579 Cd9-ps MGI:MGI:3645134 +668582 Ighv8-14 MGI:MGI:3648977|IMGT/GENE-DB:IGHV8-14 +668583 Tpt1-ps1 MGI:MGI:107797 +668584 Gm9255 MGI:MGI:3648979 +668586 Gm9256 MGI:MGI:3648981 +668588 Gm9257 MGI:MGI:3648973 +668589 Ighv1-80 MGI:MGI:4439738|IMGT/GENE-DB:IGHV1-80 +668591 Ighv1-81 MGI:MGI:4439635|IMGT/GENE-DB:IGHV1-81 +668592 Gm9258 MGI:MGI:3645726 +668594 Gm9259 MGI:MGI:3645724 +668595 Gm9260 MGI:MGI:3645725 +668597 Ighv1-85 MGI:MGI:3645723|IMGT/GENE-DB:IGHV1-85 +668599 Ighv1-86 MGI:MGI:3645729|IMGT/GENE-DB:IGHV1-86 +668603 Gm9264 MGI:MGI:3643302 +668604 1700016P03Rik MGI:MGI:1922792 +668605 Gm9265 MGI:MGI:3643307 +668606 Gm9266 MGI:MGI:3643305 +668611 Gm9267 MGI:MGI:3646453 +668612 Gm9268 MGI:MGI:3646456|Ensembl:ENSMUSG00000091528|Vega:OTTMUSG00000037916 +668614 Gm9269 MGI:MGI:3646451 +668618 Gm9271 MGI:MGI:3646449 +668620 Zfp936 MGI:MGI:3642994|Ensembl:ENSMUSG00000064194|Vega:OTTMUSG00000056302 +668622 Gm9273 MGI:MGI:3643077 +668624 Gm9274 MGI:MGI:3643071 +668625 Gm9275 MGI:MGI:3643072 +668626 Gm9276 MGI:MGI:3643073 +668629 Gm13767 MGI:MGI:3651237 +668630 Gm9278 MGI:MGI:3646238 +668632 Gm9279 MGI:MGI:3646237 +668633 Gm9280 MGI:MGI:3646236 +668634 Gm12340 MGI:MGI:3650320 +668641 Gm12733 MGI:MGI:3650214 +668645 Gm9282 MGI:MGI:3649104 +668646 Gm9283 MGI:MGI:3649101 +668647 Klk1b19-ps MGI:MGI:891985 +668648 Gm9284 MGI:MGI:3649099 +668650 Gm9285 MGI:MGI:3643136 +668653 Gm9286 MGI:MGI:3648941 +668654 Gm9287 MGI:MGI:3648945 +668655 Gm9288 MGI:MGI:3646047 +668656 Gm9289 MGI:MGI:3779842 +668659 Gm9290 MGI:MGI:3646050 +668660 Gm9291 MGI:MGI:3648892 +668661 2410002F23Rik MGI:MGI:1914226|Ensembl:ENSMUSG00000045411|Vega:OTTMUSG00000023110 +668662 Gm9292 MGI:MGI:3647448 +668664 Gm9293 MGI:MGI:3648896 +668668 Gm9294 MGI:MGI:3648888 +668671 Gm9297 MGI:MGI:3645835 +668672 Gm9298 MGI:MGI:3648083 +668674 Gm12494 MGI:MGI:3702525 +668675 Gm9299 MGI:MGI:3648098 +668677 Gm9300 MGI:MGI:3779843 +668683 Gm9302 MGI:MGI:3644401 +668686 Gm12501 MGI:MGI:3649307 +668697 Gm9305 MGI:MGI:3644841 +668699 Rpl17-ps7 MGI:MGI:3647436 +668700 Gm9308 MGI:MGI:3647522 +668701 Gm9309 MGI:MGI:3647521 +668702 Gm13808 MGI:MGI:3649745 +668705 Gm13810 MGI:MGI:3649748 +668706 Gm11425 MGI:MGI:3650957 +668709 Gm9311 MGI:MGI:3644818 +668710 Gm9312 MGI:MGI:3647775 +668712 Gm9314 MGI:MGI:3647777 +668714 Gm9315 MGI:MGI:3646775 +668716 Gm9316 MGI:MGI:3647780 +668717 Gm9317 MGI:MGI:3647781 +668719 Gm9318 MGI:MGI:3646781 +668720 Gm9319 MGI:MGI:3648811 +668723 Amy2-ps1 MGI:MGI:104546 +668724 Gm9320 MGI:MGI:3645000 +668725 Mrgpra9 MGI:MGI:3033148|Ensembl:ENSMUSG00000074111|Vega:OTTMUSG00000046358 +668726 Gm9321 MGI:MGI:3648816 +668727 Mrgpra2a MGI:MGI:3821888|Ensembl:ENSMUSG00000093973|Vega:OTTMUSG00000033704 +668729 Gm9322 MGI:MGI:3644993 +668733 Gm13884 MGI:MGI:3649663 +668736 Frg2f5 MGI:MGI:3647962 +668738 Frg2f6 MGI:MGI:3647970 +668739 Frg2f7 MGI:MGI:3648177 +668740 Mettl4-ps1 MGI:MGI:3779337 +668742 Frg2f3 MGI:MGI:3643940 +668743 Frg2f2 MGI:MGI:3643939 +668744 Gm13886 MGI:MGI:3649359 +668745 Oaz2-ps MGI:MGI:3644634 +668747 Gm9330 MGI:MGI:3645188 +668749 Gm9332 MGI:MGI:3643926 +668750 Gm9333 MGI:MGI:3643231 +668751 Gm11443 MGI:MGI:3651160 +668752 Gm9334 MGI:MGI:3648203 +668754 Gm9335 MGI:MGI:3643226 +668757 Gm9336 MGI:MGI:3643230 +668758 Fbxw28 MGI:MGI:3779847|Ensembl:ENSMUSG00000054087|Vega:OTTMUSG00000051225 +668761 Rpl27a-ps2 MGI:MGI:3645381 +668763 Gm9340 MGI:MGI:3645383 +668764 Gm9341 MGI:MGI:3645378 +668765 Gm9342 MGI:MGI:3779848 +668766 Gm9343 MGI:MGI:3645198 +668771 Gm9347 MGI:MGI:3648409 +668772 Gm9348 MGI:MGI:3644591 +668773 Gm9349 MGI:MGI:3648407 +668775 Gm9351 MGI:MGI:3648413 +668778 Gm9353 MGI:MGI:3644601 +668779 Gm9354 MGI:MGI:3647598 +668783 Gm9357 MGI:MGI:3643913 +668784 Gm9358 MGI:MGI:3643920 +668786 Gm9359 MGI:MGI:3648512 +668787 Gm9360 MGI:MGI:3643917 +668788 Gm9361 MGI:MGI:3643912 +668789 Gm9362 MGI:MGI:3643911 +668790 Gm13915 MGI:MGI:3651613 +668791 Gm9363 MGI:MGI:3647830 +668792 Gm9364 MGI:MGI:3646838 +668793 Gm11509 MGI:MGI:3650710 +668794 Gm9365 MGI:MGI:3646839 +668796 Gm9367 MGI:MGI:3647838 +668797 Gm13937 MGI:MGI:3651879 +668799 Gm13935 MGI:MGI:3651886 +668801 Gm9368 MGI:MGI:3645994 +668802 Gm13941 MGI:MGI:3651375 +668803 Atp5l-ps2 MGI:MGI:3651531 +668804 Gm9369 MGI:MGI:3645990 +668806 Gm9370 MGI:MGI:3645991 +668809 Gm9372 MGI:MGI:3645996 +668811 Gm9373 MGI:MGI:3643026 +668813 Gm9375 MGI:MGI:3643024 +668814 Gm9376 MGI:MGI:3643023|Ensembl:ENSMUSG00000092109|Vega:OTTMUSG00000050190 +668815 Gm9377 MGI:MGI:3643022 +668816 Gm9378 MGI:MGI:3643021 +668817 Gm9379 MGI:MGI:3643020 +668820 Gm9381 MGI:MGI:3644106 +668822 Olfr1296-ps1 MGI:MGI:3031130 +668825 Olfr268-ps1 MGI:MGI:3030102 +668827 Gm13928 MGI:MGI:3649213 +668829 Gm9385 MGI:MGI:3646182 +668830 Gm9386 MGI:MGI:3643270 +668831 Gm9387 MGI:MGI:3643269 +668832 Rpl31-ps25 MGI:MGI:3643272 +668835 Rpl19-ps5 MGI:MGI:3644768 +668836 Gm9390 MGI:MGI:3643268 +668837 Gm9391 MGI:MGI:3644770 +668838 Gm9392 MGI:MGI:3643262 +668840 Rpl7a-ps7 MGI:MGI:3645560 +668843 Gm9395 MGI:MGI:3645562 +668844 Gm9396 MGI:MGI:3645563 +668845 Gm9397 MGI:MGI:3645564 +668847 Gm9399 MGI:MGI:3645566 +668848 Gm9400 MGI:MGI:3645557 +668850 Rpl31-ps16 MGI:MGI:3648831 +668853 Gm15578 MGI:MGI:3783026 +668857 Gm9402 MGI:MGI:3648832 +668858 Gm9403 MGI:MGI:3648825 +668859 Gm13983 MGI:MGI:3649280 +668863 Gm9405 MGI:MGI:3645782 +668866 Gm9406 MGI:MGI:3645777 +668867 Gm9407 MGI:MGI:3645778 +668868 Gm9408 MGI:MGI:3645775 +668870 Gm9409 MGI:MGI:3649041 +668871 Gm9410 MGI:MGI:3649040 +668872 Gm9411 MGI:MGI:3649042 +668880 Stard9 MGI:MGI:3045258|Ensembl:ENSMUSG00000033705|Vega:OTTMUSG00000015627 +668882 Gm9415 MGI:MGI:3646905 +668885 Gm9416 MGI:MGI:3646902 +668887 Gm14017 MGI:MGI:3702155 +668888 Amd-ps7 MGI:MGI:3646899 +668890 Gm9419 MGI:MGI:3643978 +668892 Gm14245 MGI:MGI:3651254 +668894 Gm14025 MGI:MGI:3649276|Ensembl:ENSMUSG00000079051|Vega:OTTMUSG00000015417 +668896 Spcs2-ps MGI:MGI:3650451 +668899 Gm14044 MGI:MGI:3650452 +668905 Gm9423 MGI:MGI:3647501 +668906 Gm14098 MGI:MGI:3651961 +668907 Gm9424 MGI:MGI:3648334 +668908 Gm14101 MGI:MGI:3651973 +668910 Gm14056 MGI:MGI:3649509 +668911 Gm14053 MGI:MGI:3651943 +668913 Rpl26-ps5 MGI:MGI:3650896 +668914 Rbmx2-ps MGI:MGI:3651105 +668915 Gm14082 MGI:MGI:3651108 +668916 Gm11645 MGI:MGI:3652133 +668917 Zfp133-ps MGI:MGI:2176612|Ensembl:ENSMUSG00000083674 +668918 Gm14111 MGI:MGI:3652258 +668919 Gm14115 MGI:MGI:3652261 +668920 Gm14113 MGI:MGI:3652260 +668921 Gm9425 MGI:MGI:3643867 +668923 Zfp442 MGI:MGI:3651999|Ensembl:ENSMUSG00000068130|Vega:OTTMUSG00000015730 +668924 Gm14127 MGI:MGI:3652004 +668925 Gm14143 MGI:MGI:3649545 +668926 Gm14141 MGI:MGI:3649542 +668929 Rad21l MGI:MGI:3652039|Ensembl:ENSMUSG00000074704|Vega:OTTMUSG00000015829 +668930 Gm14156 MGI:MGI:3652034 +668931 Gm14227 MGI:MGI:3649437 +668932 Dnmt3b-ps1 MGI:MGI:2674155 +668936 Rpl5-ps2 MGI:MGI:3649355 +668938 Gm14239 MGI:MGI:3651698 +668940 Myh7b MGI:MGI:3710243|Ensembl:ENSMUSG00000074652|Vega:OTTMUSG00000016104 +668941 Gm14173 MGI:MGI:3650930 +668943 Gm14276 MGI:MGI:3701955 +668947 Gm11452 MGI:MGI:3651351 +668950 Gm11472 MGI:MGI:3650288 +668951 Gm11473 MGI:MGI:3650296 +668952 Gm14234 MGI:MGI:3651465 +668955 Gm14263 MGI:MGI:3649393 +668957 Gm14334 MGI:MGI:3649938 +668958 Btbd35f11 MGI:MGI:3709280|Ensembl:ENSMUSG00000094558|Vega:OTTMUSG00000016406 +668960 Btbd35f10 MGI:MGI:3709278|Ensembl:ENSMUSG00000095716|Vega:OTTMUSG00000016411 +668961 LOC668961 - +668963 Btbd35f20 MGI:MGI:3709274|Ensembl:ENSMUSG00000094596|Vega:OTTMUSG00000016420 +668964 Btbd35f17 MGI:MGI:3709272|Ensembl:ENSMUSG00000094273|Vega:OTTMUSG00000016437 +668965 Gm9427 MGI:MGI:3646752 +668967 Gm14370 MGI:MGI:3651565 +668968 Gm9428 MGI:MGI:3779850 +668969 Gm14366 MGI:MGI:3650558 +668970 Gm14375 MGI:MGI:3651799 +668971 Gm14451 MGI:MGI:3651432 +668972 Gm14448 MGI:MGI:3649326 +668973 Gm14395 MGI:MGI:3649577 +668974 Psmb6-ps MGI:MGI:1859621 +668975 Gm9429 MGI:MGI:3643631 +668976 Ssxb6 MGI:MGI:2446775|Ensembl:ENSMUSG00000079702|Vega:OTTMUSG00000016721 +668977 Gm9430 MGI:MGI:3643632 +668980 Gm9431 MGI:MGI:3648373 +668982 Gm14473 MGI:MGI:3650130 +668984 Gm14513 MGI:MGI:3648369 +668986 Gm9432 MGI:MGI:3648371 +668990 Gm9434 MGI:MGI:3645161 +668991 Gm9435 MGI:MGI:3645162 +668993 Csnk2a1-ps MGI:MGI:88545 +668994 Gm9436 MGI:MGI:3645165 +668995 Rpl36-ps10 MGI:MGI:3645166 +668997 Gm9439 MGI:MGI:3645164 +669000 Gm9440 MGI:MGI:3644966 +669017 Gm12490 MGI:MGI:3651827 +669120 Gm14986 MGI:MGI:3708105 +669130 Gm9442 MGI:MGI:3779852 +669149 Vmn2r88 MGI:MGI:1316662|Ensembl:ENSMUSG00000000606|Vega:OTTMUSG00000033227 +669171 Gm9443 MGI:MGI:3779853 +669207 Gm12109 MGI:MGI:3651175 +669222 Gm9445 MGI:MGI:3779855 +669278 Gm9448 MGI:MGI:3779858 +669291 Gm15363 MGI:MGI:3705833 +669301 Gm9449 MGI:MGI:3779859 +669306 Gm9450 MGI:MGI:3779860 +669309 Gm11796 MGI:MGI:3651076 +669311 Gm9451 MGI:MGI:3779861 +669389 Gm9456 MGI:MGI:3779866 +669393 Gm9457 MGI:MGI:3779867 +669402 Gm9458 MGI:MGI:3779868 +669420 Gm10129 MGI:MGI:3641890 +669429 Gm1840 MGI:MGI:3037698 +669445 Gm13007 MGI:MGI:3649722 +669557 Gm9463 MGI:MGI:3779873 +669582 Gm13359 MGI:MGI:3651940 +669675 Gm9465 MGI:MGI:3779875 +669723 Gm9466 MGI:MGI:3779876 +669737 Gm15043 MGI:MGI:3715623 +669751 Gm17756 MGI:MGI:5009846 +669778 Rpl36-ps6 MGI:MGI:3779879 +669780 Gm16527 MGI:MGI:4361133 +669792 Rpl21-ps9 MGI:MGI:3650934 +669823 Tgif1-ps MGI:MGI:3779880 +669833 Gm16463 MGI:MGI:3643937 +669853 Gm10517 MGI:MGI:3642267 +669866 Gm9472 MGI:MGI:3779882 +669965 Gm9474 MGI:MGI:3779884 +670007 Gm9476 MGI:MGI:3779885 +670059 Vmn2r125 MGI:MGI:5434138 +670074 Gm14773 MGI:MGI:3642821 +670100 Gm9480 MGI:MGI:3779890 +670110 Vmn2r-ps13 MGI:MGI:3757946 +670124 Gm12468 MGI:MGI:3652115 +670198 Gm10734 MGI:MGI:3642559 +670211 Gm12508 MGI:MGI:3651359 +670250 Gm9481 MGI:MGI:3779891 +670263 Gm14826 MGI:MGI:3705650 +670326 Gm16425 MGI:MGI:3643338 +670358 Gm9484 MGI:MGI:3779894 +670453 Ccnb2-ps MGI:MGI:3779896 +670464 Gm11596 MGI:MGI:3652177|Ensembl:ENSMUSG00000078261|Vega:OTTMUSG00000002547 +670467 Gm9487 MGI:MGI:3779897 +670472 Gm11569 MGI:MGI:3709346|Ensembl:ENSMUSG00000078260|Vega:OTTMUSG00000002208 +670482 Gm11554 MGI:MGI:3705237|Ensembl:ENSMUSG00000078259|Vega:OTTMUSG00000002180 +670495 Gm9488 MGI:MGI:3779898 +670496 Gm11564 MGI:MGI:3650329|Ensembl:ENSMUSG00000078258|Vega:OTTMUSG00000002201 +670507 Gm14317 MGI:MGI:3651690 +670533 Gm11567 MGI:MGI:3649436|Ensembl:ENSMUSG00000059845|Vega:OTTMUSG00000002206 +670534 Vmn2r-ps124 MGI:MGI:3761610 +670550 Gm11565 MGI:MGI:3650327|Ensembl:ENSMUSG00000078256|Vega:OTTMUSG00000002203 +670558 H60c MGI:MGI:3774845|Ensembl:ENSMUSG00000091618|Vega:OTTMUSG00000063464 +670565 Gm9493 MGI:MGI:3779903 +670593 Gm9495 MGI:MGI:3779905|Ensembl:ENSMUSG00000107280|Vega:OTTMUSG00000056184 +670603 Gm9496 MGI:MGI:3779906 +670671 Gm9497 MGI:MGI:3779907 +670673 Gm9498 MGI:MGI:3779908 +670708 Gm9499 MGI:MGI:3779909 +670717 Gm10108 MGI:MGI:3642431 +670727 Gm15412 MGI:MGI:3705100|Ensembl:ENSMUSG00000085751 +670764 Vmn1r124 MGI:MGI:3779910|Ensembl:ENSMUSG00000094221|Vega:OTTMUSG00000038161 +670773 Gm9501 MGI:MGI:3779911 +670775 Gm11468 MGI:MGI:3649218|Ensembl:ENSMUSG00000084840 +670795 Gm9502 MGI:MGI:3779912 +670819 Gm9504 MGI:MGI:3779914 +670832 Rps12-ps10 MGI:MGI:3649508 +670833 Gm11213 MGI:MGI:3701774|Ensembl:ENSMUSG00000084782|Vega:OTTMUSG00000000252 +670857 Vmn1r159 MGI:MGI:3642763|Ensembl:ENSMUSG00000095931|Vega:OTTMUSG00000038039 +670864 Gm9506 MGI:MGI:3779916 +670880 Gm9507 MGI:MGI:3779917 +670895 Gm9508 MGI:MGI:3779918|Ensembl:ENSMUSG00000112170 +670911 Gm9509 MGI:MGI:3779919 +670912 Gm9510 MGI:MGI:3779920 +670921 Gm16471 MGI:MGI:3645357 +670926 Vmn2r-ps69 MGI:MGI:3761310 +670940 Vmn2r70 MGI:MGI:3761314|Ensembl:ENSMUSG00000090806|Vega:OTTMUSG00000037814 +670994 Gm9512 MGI:MGI:3779922 +671003 Gm9513 MGI:MGI:3779923|Ensembl:ENSMUSG00000090710|Vega:OTTMUSG00000044740 +671007 Gm9514 MGI:MGI:3779924 +671031 Gm9515 MGI:MGI:3779925 +671033 Gm15170 MGI:MGI:3705718 +671052 Gm9516 MGI:MGI:3779926 +671064 Gm11225 MGI:MGI:3651505 +671132 Gm9519 MGI:MGI:3779928|Ensembl:ENSMUSG00000108654 +671141 Pou2f3-rs1 MGI:MGI:103144 +671182 Gm9520 MGI:MGI:3779929 +671190 Gm9521 MGI:MGI:3779930 +671215 Gm9522 MGI:MGI:3779931 +671222 Gm9523 MGI:MGI:3779932 +671232 Topaz1 MGI:MGI:3779933|Ensembl:ENSMUSG00000094985|Vega:OTTMUSG00000062746 +671242 Gm9525 MGI:MGI:3779934 +671250 Gm16459 MGI:MGI:3644110 +671297 Gm14856 MGI:MGI:3705357 +671322 Gm9529 MGI:MGI:3779938 +671336 Gm9530 MGI:MGI:3779939|Ensembl:ENSMUSG00000096950 +671357 Vmn2r-ps110 MGI:MGI:3761529 +671392 Gm9531 MGI:MGI:3779940 +671410 Gm9534 MGI:MGI:3779943 +671439 Gm9535 MGI:MGI:3779945 +671466 Gm14024 MGI:MGI:3649704 +671504 Gm9536 MGI:MGI:3779946 +671535 Parp10 MGI:MGI:3712326|Ensembl:ENSMUSG00000063268|Vega:OTTMUSG00000035244 +671564 Rnf212 MGI:MGI:3645767|Ensembl:ENSMUSG00000055385|Vega:OTTMUSG00000054023 +671621 Gm9537 MGI:MGI:3779947 +671636 Gm14660 MGI:MGI:3705728 +671641 Rps12-ps24 MGI:MGI:3642518 +671650 Gm20783 MGI:MGI:5434139 +671652 Trav7-1 MGI:MGI:3647460|IMGT/GENE-DB:TRAV7-1 +671653 Gm9538 MGI:MGI:3779948 +671692 Gm11718 MGI:MGI:3649216 +671695 Vmn2r-ps22 MGI:MGI:3761466 +671706 Gm9540 MGI:MGI:3779950 +671731 Gm9541 MGI:MGI:3779951 +671741 Gm16411 MGI:MGI:3647793 +671840 Gm14668 MGI:MGI:3707967 +671842 Gm13754 MGI:MGI:3651213 +671878 Sms-ps MGI:MGI:3705601 +671917 LOC671917 Ensembl:ENSMUSG00000094915 +671927 Trav9d-1 MGI:MGI:3650631|IMGT/GENE-DB:TRAV9D-1 +671950 Gm14702 MGI:MGI:3705355 +671971 Gm9544 MGI:MGI:3779954 +671994 Hspd1-ps1 MGI:MGI:3779956 +672025 LOC672025 - +672095 Gm9547 MGI:MGI:3779957 +672098 Gm9548 MGI:MGI:3779958 +672125 Gm14496 MGI:MGI:3769929|Ensembl:ENSMUSG00000098505 +672161 Gm9550 MGI:MGI:3779960 +672187 Gm9551 MGI:MGI:3779961 +672195 Gm10053 MGI:MGI:3704493 +672208 Gm9553 MGI:MGI:3779963 +672214 Gm10136 MGI:MGI:3704242 +672217 Gm9555 MGI:MGI:3779965 +672230 Gm13254 MGI:MGI:3652190 +672284 Nkx1-1 MGI:MGI:109346|Ensembl:ENSMUSG00000029112|Vega:OTTMUSG00000045986 +672302 Gm9556 MGI:MGI:3779966 +672329 Igkvk33-85 - +672372 Gm9557 MGI:MGI:3779967 +672381 Gm13690 MGI:MGI:3652065 +672398 Gm9558 MGI:MGI:3779968 +672405 Gm9560 MGI:MGI:3779970 +672445 Gm10266 MGI:MGI:3708644 +672450 LOC672450 - +672490 Gm9563 MGI:MGI:3779973 +672495 Gm16464 MGI:MGI:3643716 +672498 Gm9564 MGI:MGI:3779974 +672505 Gm9566 MGI:MGI:3779976 +672511 Rnf213 MGI:MGI:1289196|Ensembl:ENSMUSG00000070327|Vega:OTTMUSG00000003910 +672553 Gm9567 MGI:MGI:3779977 +672572 Gm9568 MGI:MGI:3779978 +672598 Gm9569 MGI:MGI:3779979 +672614 Gm9570 MGI:MGI:3779980 +672637 Gm12085 MGI:MGI:3650335 +672682 Gm9573 MGI:MGI:3779983|Ensembl:ENSMUSG00000090588|Vega:OTTMUSG00000037249 +672740 Defa-ps6 MGI:MGI:3705855 +672763 Gm13710 MGI:MGI:3650894|Ensembl:ENSMUSG00000087362 +672778 Gm9575 MGI:MGI:3779984 +672799 Rpl37a-ps2 MGI:MGI:3779985 +672822 Gm9577 MGI:MGI:3779986 +672828 Gm9578 MGI:MGI:3779987 +672857 Gm9580 MGI:MGI:3811203 +672902 Gm9583 MGI:MGI:3779991 +672931 Gm9584 MGI:MGI:3779992 +672934 Gm9585 MGI:MGI:3779993 +672951 Vmn2r-ps7 MGI:MGI:3757679 +672959 Rps12l1 MGI:MGI:3783241 +672972 Gm9586 MGI:MGI:3779995 +672977 Gm9587 MGI:MGI:3779996 +673094 Cd99 MGI:MGI:1913728 +673132 Gm16506 MGI:MGI:3641772 +673151 Gm20784 MGI:MGI:5434140 +673191 LOC673191 - +673215 Gm9591 MGI:MGI:3780000 +673222 Rpl31-ps6 MGI:MGI:3783190 +673290 Gm9593 MGI:MGI:3780002 +673332 Gm9595 MGI:MGI:3780004 +673380 Gm9597 MGI:MGI:3780005 +673535 Gm9598 MGI:MGI:3780006 +673582 Rpl31-ps17 MGI:MGI:3648194 +673604 Gm9599 MGI:MGI:3780007 +673652 LOC673652 - +673676 Gm9602 MGI:MGI:3780010|Ensembl:ENSMUSG00000090539|Vega:OTTMUSG00000036241 +673685 Gm9603 MGI:MGI:3780011 +673742 Gm9604 MGI:MGI:3780012 +673743 Gm14353 MGI:MGI:3650960 +673754 Gm20786 MGI:MGI:5434142 +673817 Gm16479 MGI:MGI:3643626 +673902 Vmn1r-ps74 MGI:MGI:3780015 +673977 Vmn1r107 MGI:MGI:3780017|Ensembl:ENSMUSG00000095275|Vega:OTTMUSG00000038200 +674011 LOC674011 - +674018 Ighv1-61 MGI:MGI:4439824|IMGT/GENE-DB:IGHV1-61 +674032 Gm9611 MGI:MGI:3780019 +674052 Ps-modr4 - +674078 Ighv134 - +674080 LOC674080 - +674082 Vhq52.a22.67 - +674098 Trav8-1 MGI:MGI:3649608|IMGT/GENE-DB:TRAV8-1 +674122 Gm16410 MGI:MGI:3648382 +674135 Gm9574 MGI:MGI:3809525 +674152 Lgals1-ps1 MGI:MGI:3780020 +674169 Gm9613 MGI:MGI:3780021 +674190 LOC674190 - +674202 Gm13921 MGI:MGI:3651614 +674207 Gm9614 MGI:MGI:3780022 +674214 Gm9615 MGI:MGI:3780023|Ensembl:ENSMUSG00000096237 +674228 Gm9616 MGI:MGI:3780024 +674251 Adgrd2-ps MGI:MGI:2685845 +674277 Gm9618 MGI:MGI:3780026 +674283 Gm20561 MGI:MGI:5295668 +674310 Gm12267 MGI:MGI:3651211 +674318 Gm16420 MGI:MGI:3643246 +674324 Gm9619 MGI:MGI:3780027 +674332 Gm9620 MGI:MGI:3780028 +674360 Vmn2r-ps89 MGI:MGI:3757941 +674371 Gm9621 MGI:MGI:3780029 +674396 Gm16465 MGI:MGI:3646326 +674419 Rpl7a-ps5 MGI:MGI:3643553 +674469 Gm14472 MGI:MGI:3650138 +674597 Gm9625 MGI:MGI:3780033 +674699 Gm9626 MGI:MGI:3780034 +674723 Gm9628 MGI:MGI:3780036 +674819 Gm9630 MGI:MGI:3780038 +674842 Gm9631 MGI:MGI:3800296 +674895 Nek10 MGI:MGI:2685128|Ensembl:ENSMUSG00000042567|Vega:OTTMUSG00000027768 +674896 Gm29690 MGI:MGI:5588849 +674908 Gm9632 MGI:MGI:3780039 +674920 Gm15364 MGI:MGI:3707584 +674921 Gm13623 MGI:MGI:3649578 +674926 Gm9633 MGI:MGI:3780040 +674940 Gm13559 MGI:MGI:3651672 +675062 Gm15002 MGI:MGI:3705342 +675063 Gm9634 MGI:MGI:3780041 +675165 Gm9637 MGI:MGI:3804942 +675190 Vmn2r-ps91 MGI:MGI:3761339 +675278 Rpl21-ps15 MGI:MGI:3705426 +675294 Gm9639 MGI:MGI:3780046|Ensembl:ENSMUSG00000096131 +675306 Gm12579 MGI:MGI:3651711 +675325 2410017I17Rik MGI:MGI:1916967|Ensembl:ENSMUSG00000038311 +675347 Gm20787 MGI:MGI:5434143 +675363 Gm9640 MGI:MGI:3780047 +675380 Gm16481 MGI:MGI:3648374 +675416 Gm14506 MGI:MGI:3705552 +675440 Gm13430 MGI:MGI:3651032 +675463 Gm9643 MGI:MGI:3780050 +675498 Gm29691 MGI:MGI:5588850 +675507 Gm9644 MGI:MGI:3780051 +675514 Gm15191 MGI:MGI:3708125 +675537 Gm9645 MGI:MGI:3780052 +675558 Gm14531 MGI:MGI:3705410 +675566 Rps19-ps8 MGI:MGI:3780053 +675578 Gm9648 MGI:MGI:3780055 +675593 Spin3-ps MGI:MGI:3780056 +675689 Gm12171 MGI:MGI:3649516 +675713 Gm17758 MGI:MGI:5009848 +675749 Gm10693 MGI:MGI:3704277|Ensembl:ENSMUSG00000074420 +675762 Gm9652 MGI:MGI:3780060 +675800 Gm9655 MGI:MGI:3780063 +675812 Zfp605 MGI:MGI:2444933|Ensembl:ENSMUSG00000023284|Vega:OTTMUSG00000022595 +675824 Gm16394 MGI:MGI:3644766 +675912 Gm13377 MGI:MGI:3649914 +675921 Tnk2os MGI:MGI:3642140|Ensembl:ENSMUSG00000075265 +675947 LOC675947 - +675957 Mlnr-ps MGI:MGI:3780065 +675960 Gm9658 MGI:MGI:3780066 +675966 Gm9659 MGI:MGI:3780067 +675969 Vmn2r76 MGI:MGI:3761332|Ensembl:ENSMUSG00000091239|Vega:OTTMUSG00000037756 +675985 Rps6-ps2 MGI:MGI:3646827 +675987 Gm9661 MGI:MGI:3780069 +676037 Gm9662 MGI:MGI:3780070 +676072 Gm12983 MGI:MGI:3651378 +676077 Gm14613 MGI:MGI:3642911 +676157 Gm9665 MGI:MGI:3780073 +676191 Gm11434 MGI:MGI:3651717 +676200 Cyp2d38-ps MGI:MGI:3780075 +676246 Gm9670 MGI:MGI:3780078 +676253 Gm14648 MGI:MGI:3705508 +676294 Gm9671 MGI:MGI:3780079 +676304 Gm9672 MGI:MGI:3780080 +676331 Gm9673 MGI:MGI:3780081 +676369 Gm14340 MGI:MGI:3650817 +676433 Gm9678 MGI:MGI:3780086 +676478 LOC676478 - +676484 Gm9679 MGI:MGI:3780087 +676527 Gm12248 MGI:MGI:3651124|Ensembl:ENSMUSG00000086962 +676548 Gm9682 MGI:MGI:3780090 +676564 Gm10064 MGI:MGI:3645905 +676568 Gm9683 MGI:MGI:3780091 +676623 Gm14622 MGI:MGI:3805545 +676676 F530104D19Rik MGI:MGI:3642424 +676688 Gm9685 MGI:MGI:3780093 +676689 LOC676689 - +676712 Gm9687 MGI:MGI:3780095 +676750 Gm9689 MGI:MGI:3780097 +676837 Gm38417 MGI:MGI:5621302 +676882 Gm9693 MGI:MGI:3780101 +676894 Gm9694 MGI:MGI:3780102 +676914 Gm9696 MGI:MGI:3819177|Ensembl:ENSMUSG00000070465 +676915 Gm9697 MGI:MGI:3780104 +676918 Gm20788 MGI:MGI:5434144 +676923 Gm16470 MGI:MGI:3645079 +676954 Gm9699 MGI:MGI:3780106 +676965 Gm9700 MGI:MGI:3780107 +676982 Gm20789 MGI:MGI:5434145 +676984 Gm9701 MGI:MGI:3780108 +676992 Gm17761 MGI:MGI:5009851 +676997 Gm9702 MGI:MGI:3780109 +677008 LOC677008 - +677010 Gm9703 MGI:MGI:3780110 +677027 Rps15a-ps3 MGI:MGI:3650886 +677044 Gm10653 MGI:MGI:3642572|Ensembl:ENSMUSG00000074250 +677073 Gm16477 MGI:MGI:3646779 +677155 Gm15703 MGI:MGI:3783143 +677156 Cyp4f37 MGI:MGI:3780112|Ensembl:ENSMUSG00000062464 +677168 Gm9706 MGI:MGI:3780113 +677205 Gm16433 MGI:MGI:3645626 +677233 Scgb1b6-ps MGI:MGI:3780117 +677260 Gm13902 MGI:MGI:3652326 +677270 Gm9710 MGI:MGI:3780118 +677289 Prr33 MGI:MGI:3642289|Ensembl:ENSMUSG00000043795 +677296 Fcrl6 MGI:MGI:3618339|Ensembl:ENSMUSG00000070504|Vega:OTTMUSG00000050154 +677315 Gm9711 MGI:MGI:3780119 +677321 Gm9712 MGI:MGI:3780120 +677338 Gm9714 MGI:MGI:3780122 +677379 Gm14088 MGI:MGI:3650492 +677423 Gm9715 MGI:MGI:3780123 +677440 Clec2j MGI:MGI:3647940 +677448 Gm16385 MGI:MGI:3780125 +677457 Gm9717 MGI:MGI:3780126 +677501 Gm9719 MGI:MGI:3780128 +677512 Sult2a-ps4 MGI:MGI:3705831 +677525 LOC677525 - +677561 Gm15375 MGI:MGI:3705815 +677613 Gm9721 MGI:MGI:3780130 +677682 Itpa-ps3 MGI:MGI:3613365 +677785 Gm9722 MGI:MGI:3646115 +677786 Gm12229 MGI:MGI:3649743 +677788 Gm9723 MGI:MGI:3780131 +677858 Igkv8-24 MGI:MGI:4947958|IMGT/GENE-DB:IGKV8-24 +677861 Igkv12-42 MGI:MGI:5009852|IMGT/GENE-DB:IGKV12-42 +677884 Pakap MGI:MGI:5141924|Ensembl:ENSMUSG00000089945|Vega:OTTMUSG00000007263 +692105 Igkv13-54-1 MGI:MGI:5009853|IMGT/GENE-DB:IGKV13-54-1 +692112 Igkv13-55-1 MGI:MGI:5009854|IMGT/GENE-DB:IGKV13-55-1 +692113 Igkv13-56-1 MGI:MGI:5009855|IMGT/GENE-DB:IGKV13-56-1 +692114 Igkv13-57-1 MGI:MGI:5009856|IMGT/GENE-DB:IGKV13-57-1 +692118 Igkv13-61-1 MGI:MGI:5009857|IMGT/GENE-DB:IGKV13-61-1 +692119 Igkv13-62-1 MGI:MGI:5009858|IMGT/GENE-DB:IGKV13-62-1 +692132 Trappc3l MGI:MGI:3642034|Ensembl:ENSMUSG00000071340 +692133 Igkv12-66 MGI:MGI:5009859|IMGT/GENE-DB:IGKV12-66 +692138 Igkv13-71-1 MGI:MGI:5009860|IMGT/GENE-DB:IGKV13-71-1 +692139 Igkv13-73-1 MGI:MGI:5009861|IMGT/GENE-DB:IGKV13-73-1 +692140 Igkv13-74-1 MGI:MGI:5009862|IMGT/GENE-DB:IGKV13-74-1 +692141 Igkv4-75 MGI:MGI:5009863|IMGT/GENE-DB:IGKV4-75 +692142 Igkv13-76 MGI:MGI:5009864|IMGT/GENE-DB:IGKV13-76 +692143 Igkv13-80-1 MGI:MGI:5009865|IMGT/GENE-DB:IGKV13-80-1 +692144 Igkv13-82 MGI:MGI:5009866|IMGT/GENE-DB:IGKV13-82 +692145 Igkv4-83 MGI:MGI:5009867|IMGT/GENE-DB:IGKV4-83 +692152 Igkv13-84 MGI:MGI:96514|IMGT/GENE-DB:IGKV13-84 +692153 Igkv13-87 MGI:MGI:3779399|IMGT/GENE-DB:IGKV13-87 +692154 Igkv1-88 MGI:MGI:4439828|IMGT/GENE-DB:IGKV1-88 +692155 Igkv13-89-1 MGI:MGI:5009868|IMGT/GENE-DB:IGKV13-89-1 +692161 Igkv19-93 MGI:MGI:107617|IMGT/GENE-DB:IGKV19-93 +692162 Igkv2-93-1 MGI:MGI:5009869|IMGT/GENE-DB:IGKV2-93-1 +692163 Igkv2-95-1 MGI:MGI:5009870|IMGT/GENE-DB:IGKV2-95-1 +692164 Igkv2-95-2 MGI:MGI:4937167|IMGT/GENE-DB:IGKV2-95-2 +692165 Igkv10-96 MGI:MGI:4439561|IMGT/GENE-DB:IGKV10-96 +692166 Igkv15-97 MGI:MGI:5009871|IMGT/GENE-DB:IGKV15-97 +692167 Igkv15-101-1 MGI:MGI:5009872|IMGT/GENE-DB:IGKV15-101-1 +692168 Igkv15-101 MGI:MGI:5009873|IMGT/GENE-DB:IGKV15-101 +692169 Igkv15-103 MGI:MGI:96513|IMGT/GENE-DB:IGKV15-103 +692170 Igkv2-105 MGI:MGI:5009874|IMGT/GENE-DB:IGKV2-105 +692171 Igkv15-102 MGI:MGI:5009875|IMGT/GENE-DB:IGKV15-102 +692172 Igkv2-113 MGI:MGI:5009876|IMGT/GENE-DB:IGKV2-113 +692173 Igkv11-114 MGI:MGI:5009877|IMGT/GENE-DB:IGKV11-114 +692174 Igkv11-118 MGI:MGI:5009878|IMGT/GENE-DB:IGKV11-118 +692175 Igkv14-118-1 MGI:MGI:5009879|IMGT/GENE-DB:IGKV14-118-1 +692176 Igkv14-118-2 MGI:MGI:5009880|IMGT/GENE-DB:IGKV14-118-2 +692177 Igkv9-119 MGI:MGI:5009881|IMGT/GENE-DB:IGKV9-119 +692179 Igk-V21 MGI:MGI:96507 +692180 Igkv14-126-1 MGI:MGI:5009882|IMGT/GENE-DB:IGKV14-126-1 +692181 Igkv9-128 MGI:MGI:3809196|IMGT/GENE-DB:IGKV9-128 +692182 Igkv9-129 MGI:MGI:3525017|IMGT/GENE-DB:IGKV9-129 +692184 Igkv17-134 MGI:MGI:4936953|IMGT/GENE-DB:IGKV17-134 +692185 Igkv14-134-1 MGI:MGI:5009883 +692186 Igkv1-136 MGI:MGI:4947614|IMGT/GENE-DB:IGKV1-136 +692187 Igkv2-137 MGI:MGI:4439879|IMGT/GENE-DB:IGKV2-137 +692245 Igkv12-46 MGI:MGI:4439773|IMGT/GENE-DB:IGKV12-46 +723792 Pinc MGI:MGI:3623820 +723814 Mir223 MGI:MGI:2684360|Ensembl:ENSMUSG00000076066|miRBase:MI0000703 +723815 Mir128-2 MGI:MGI:3618709|Ensembl:ENSMUSG00000065441|miRBase:MI0000726 +723816 Mir130b MGI:MGI:3618716|Ensembl:ENSMUSG00000065572|miRBase:MI0000408 +723817 Mir133b MGI:MGI:3618720|Ensembl:ENSMUSG00000065480|miRBase:MI0000821 +723818 Mir135b MGI:MGI:3618732|Ensembl:ENSMUSG00000065435|miRBase:MI0000646 +723819 Mir181c MGI:MGI:3618737|Ensembl:ENSMUSG00000065483|miRBase:MI0000724 +723820 Mir196b MGI:MGI:3618741|Ensembl:ENSMUSG00000065443|miRBase:MI0001151 +723821 Mir199a-2 MGI:MGI:3618742|Ensembl:ENSMUSG00000070126|miRBase:MI0000713 +723822 Mir218-1 MGI:MGI:3618751|Ensembl:ENSMUSG00000065603|miRBase:MI0000700 +723823 Mir219a-1 MGI:MGI:3618753|Ensembl:ENSMUSG00000065555|miRBase:MI0000702 +723824 Mir103-1 MGI:MGI:3619058|Ensembl:ENSMUSG00000065553|miRBase:MI0000587 +723825 Mir103-2 MGI:MGI:3619059|Ensembl:ENSMUSG00000065563|miRBase:MI0000588 +723826 Mir107 MGI:MGI:3619063|Ensembl:ENSMUSG00000065594|miRBase:MI0000684 +723827 Mir221 MGI:MGI:3619066|Ensembl:ENSMUSG00000065422|miRBase:MI0000709 +723828 Mir222 MGI:MGI:3619118|Ensembl:ENSMUSG00000065471|miRBase:MI0000710 +723829 Mir106a MGI:MGI:3619120|Ensembl:ENSMUSG00000065456|miRBase:MI0000406 +723830 Mir28a MGI:MGI:3619267|Ensembl:ENSMUSG00000065494|miRBase:MI0000690 +723831 Mir297-1 MGI:MGI:3619319|Ensembl:ENSMUSG00000094316|miRBase:MI0000395 +723832 Mir298 MGI:MGI:3619321|Ensembl:ENSMUSG00000065410|miRBase:MI0000398 +723833 Mir300 MGI:MGI:3619323|Ensembl:ENSMUSG00000098807|miRBase:MI0000400 +723834 Mir301 MGI:MGI:3619324|Ensembl:ENSMUSG00000065589|miRBase:MI0000401 +723835 Mir302c MGI:MGI:3619327|Ensembl:ENSMUSG00000065482|miRBase:MI0003717 +723836 Mir30e MGI:MGI:3619329|Ensembl:ENSMUSG00000065409|miRBase:MI0000259 +723837 Mir32 MGI:MGI:3619331|Ensembl:ENSMUSG00000065544|miRBase:MI0000691 +723838 Mir320 MGI:MGI:3619332|Ensembl:ENSMUSG00000065528|miRBase:MI0000704 +723839 Mir323 MGI:MGI:3619334|Ensembl:ENSMUSG00000065617|miRBase:MI0000592 +723840 Mir326 MGI:MGI:3619338|Ensembl:ENSMUSG00000065571|miRBase:MI0000598 +723841 Mir328 MGI:MGI:3619340|Ensembl:ENSMUSG00000070130|miRBase:MI0000603 +723842 Mir329 MGI:MGI:3619341|Ensembl:ENSMUSG00000065577|miRBase:MI0000605 +723843 Mir337 MGI:MGI:3619351|Ensembl:ENSMUSG00000065526|miRBase:MI0000615 +723844 Mir338 MGI:MGI:3619352|Ensembl:ENSMUSG00000065600|miRBase:MI0000619 +723845 Mir340 MGI:MGI:3619355|Ensembl:ENSMUSG00000065417|miRBase:MI0000623 +723846 Mir341 MGI:MGI:3619357|Ensembl:ENSMUSG00000070101|miRBase:MI0000625 +723847 Mir346 MGI:MGI:3619362|Ensembl:ENSMUSG00000065481|miRBase:MI0000634 +723848 Mir34a MGI:MGI:3619363|Ensembl:ENSMUSG00000065493|miRBase:MI0000584 +723849 Mir34b MGI:MGI:3619364|Ensembl:ENSMUSG00000065492|miRBase:MI0000404 +723850 Mir361 MGI:MGI:3619368|Ensembl:ENSMUSG00000065510|miRBase:MI0000761 +723851 Mir362 MGI:MGI:3619369|Ensembl:ENSMUSG00000070100|miRBase:MI0000763 +723852 Mir363 MGI:MGI:3619370|Ensembl:ENSMUSG00000070106|miRBase:MI0000765 +723853 Mir365-2 MGI:MGI:3619372|Ensembl:ENSMUSG00000065489|miRBase:MI0001645 +723854 Mir370 MGI:MGI:3619375|Ensembl:ENSMUSG00000065433|miRBase:MI0001165 +723855 Mir376a MGI:MGI:3619377|Ensembl:ENSMUSG00000105178|miRBase:MI0000793 +723856 Mir376c MGI:MGI:3619381|Ensembl:ENSMUSG00000076006|miRBase:MI0003533 +723857 Mir377 MGI:MGI:3619382|Ensembl:ENSMUSG00000065438|miRBase:MI0000794 +723858 Mir379 MGI:MGI:3619386|Ensembl:ENSMUSG00000065498|miRBase:MI0000796 +723859 Mir380 MGI:MGI:3619389|Ensembl:ENSMUSG00000104582|miRBase:MI0000797 +723860 Mir383 MGI:MGI:3619393|Ensembl:ENSMUSG00000065457|miRBase:MI0000800 +723861 Mir384 MGI:MGI:3619394|Ensembl:ENSMUSG00000065499|miRBase:MI0001146 +723862 Mir409 MGI:MGI:3619396|Ensembl:ENSMUSG00000105849|miRBase:MI0001160 +723863 Mir410 MGI:MGI:3619398|Ensembl:ENSMUSG00000065497|miRBase:MI0001161 +723864 Mir425 MGI:MGI:3619401|Ensembl:ENSMUSG00000065579|miRBase:MI0001447 +723865 Mir429 MGI:MGI:3619402|Ensembl:ENSMUSG00000065427|miRBase:MI0001642 +723866 Mir431 MGI:MGI:3619403|Ensembl:ENSMUSG00000070080|miRBase:MI0001524 +723867 Mir434 MGI:MGI:3619405|Ensembl:ENSMUSG00000070133|miRBase:MI0001526 +723868 Mir449a MGI:MGI:3619407|Ensembl:ENSMUSG00000065575|miRBase:MI0001649 +723869 Mir450-1 MGI:MGI:3619410|Ensembl:ENSMUSG00000065486|miRBase:MI0001653 +723870 Mir451a MGI:MGI:3619412|Ensembl:ENSMUSG00000070065|miRBase:MI0001730 +723871 Mir468 MGI:MGI:3619414|Ensembl:ENSMUSG00000106253|miRBase:MI0002403 +723873 Mir470 MGI:MGI:3619418|Ensembl:ENSMUSG00000070073|miRBase:MI0002405 +723874 Mir483 MGI:MGI:3619420|Ensembl:ENSMUSG00000070140|miRBase:MI0003484 +723875 Mir485 MGI:MGI:3619422|Ensembl:ENSMUSG00000070128|miRBase:MI0003492 +723876 Mir486 MGI:MGI:3619423|Ensembl:ENSMUSG00000070084|miRBase:MI0003493 +723877 Mir489 MGI:MGI:3619425|Ensembl:ENSMUSG00000070107|miRBase:MI0003476 +723878 Mir494 MGI:MGI:3619426|Ensembl:ENSMUSG00000070141|miRBase:MI0003532 +723879 Mir503 MGI:MGI:3619428|Ensembl:ENSMUSG00000076122|miRBase:MI0003538 +723880 Mir540 MGI:MGI:3619429|Ensembl:ENSMUSG00000072900|miRBase:MI0003518 +723881 Mir543 MGI:MGI:3619432|Ensembl:ENSMUSG00000076241|miRBase:MI0003519 +723882 Mir546 MGI:MGI:3619433|Ensembl:ENSMUSG00000072837|miRBase:MI0003517 +723883 Mir7b MGI:MGI:3619435|Ensembl:ENSMUSG00000065491|miRBase:MI0000730 +723884 Mir7-2 MGI:MGI:3619437|Ensembl:ENSMUSG00000065609|miRBase:MI0000729 +723885 Mir93 MGI:MGI:3619439|Ensembl:ENSMUSG00000065527|miRBase:MI0000581 +723886 Mir96 MGI:MGI:3619440|Ensembl:ENSMUSG00000065586|miRBase:MI0000583 +723887 Mir463 MGI:MGI:3619451|Ensembl:ENSMUSG00000070078|miRBase:MI0002398 +723888 Mir465 MGI:MGI:3619453|Ensembl:ENSMUSG00000070071|miRBase:MI0002400 +723889 Mir378a MGI:MGI:3617791|Ensembl:ENSMUSG00000105200|miRBase:MI0000795 +723890 Mir181b-1 MGI:MGI:3618735|Ensembl:ENSMUSG00000065458|miRBase:MI0000723 +723891 Mir19a MGI:MGI:3618743|Ensembl:ENSMUSG00000065416|miRBase:MI0000688 +723892 Mir100 MGI:MGI:3619057|Ensembl:ENSMUSG00000093011|miRBase:MI0000692 +723893 Mir10a MGI:MGI:3619064|Ensembl:ENSMUSG00000065519|miRBase:MI0000685 +723894 Mir224 MGI:MGI:3619129|Ensembl:ENSMUSG00000065542|miRBase:MI0000711 +723895 Mir31 MGI:MGI:3619330|Ensembl:ENSMUSG00000065408|miRBase:MI0000579 +723896 Mir324 MGI:MGI:3619335|Ensembl:ENSMUSG00000065534|miRBase:MI0000595 +723897 Mir33 MGI:MGI:3619343|Ensembl:ENSMUSG00000065465|miRBase:MI0000707 +723898 Mir339 MGI:MGI:3619354|Ensembl:ENSMUSG00000065593|miRBase:MI0000621 +723899 Mir365-1 MGI:MGI:3619371|Ensembl:ENSMUSG00000065449|miRBase:MI0000768 +723900 Mir375 MGI:MGI:3619376|Ensembl:ENSMUSG00000065616|miRBase:MI0000792 +723901 Mir542 MGI:MGI:3619431|Ensembl:ENSMUSG00000076140|miRBase:MI0003522 +723902 Mir7-1 MGI:MGI:3619436|Ensembl:ENSMUSG00000065434|miRBase:MI0000728 +723903 Mir181b-2 MGI:MGI:3618736|Ensembl:ENSMUSG00000065578|miRBase:MI0000823 +723904 Mir219a-2 MGI:MGI:3618754|Ensembl:ENSMUSG00000065485|miRBase:MI0000741 +723905 Mir17 MGI:MGI:3619065|Ensembl:ENSMUSG00000065508|miRBase:MI0000687 +723906 Mir296 MGI:MGI:3619269|Ensembl:ENSMUSG00000065521|miRBase:MI0000394 +723907 Mir322 MGI:MGI:3619333|Ensembl:ENSMUSG00000065418|miRBase:MI0000590 +723908 Mir331 MGI:MGI:3619347|Ensembl:ENSMUSG00000065607|miRBase:MI0000609 +723909 Mir342 MGI:MGI:3619358|Ensembl:ENSMUSG00000065436|miRBase:MI0000627 +723910 Mir351 MGI:MGI:3619367|Ensembl:ENSMUSG00000065503|miRBase:MI0000643 +723911 Mir367 MGI:MGI:3619373|Ensembl:ENSMUSG00000065413|miRBase:MI0003531 +723912 Mir382 MGI:MGI:3619392|Ensembl:ENSMUSG00000065428|miRBase:MI0000799 +723913 Mir412 MGI:MGI:3619400|Ensembl:ENSMUSG00000065570|miRBase:MI0001164 +723914 Mir448 MGI:MGI:3619406|Ensembl:ENSMUSG00000065450|miRBase:MI0001638 +723916 Mir484 MGI:MGI:3619421|Ensembl:ENSMUSG00000070074|miRBase:MI0003491 +723917 Mir539 MGI:MGI:3619427|Ensembl:ENSMUSG00000076063|miRBase:MI0003520 +723918 Mir547 MGI:MGI:3619434|Ensembl:ENSMUSG00000076005|miRBase:MI0003523 +723919 Mir452 MGI:MGI:3619450|Ensembl:ENSMUSG00000070138|miRBase:MI0001734 +723920 Mir302a MGI:MGI:3619325|Ensembl:ENSMUSG00000065552|miRBase:MI0000402 +723921 Mir350 MGI:MGI:3619366|Ensembl:ENSMUSG00000065573|miRBase:MI0000640 +723922 Mir466 MGI:MGI:3619454|Ensembl:ENSMUSG00000070099|miRBase:MI0002401 +723923 Mir20b MGI:MGI:3618748|Ensembl:ENSMUSG00000076041|miRBase:MI0003536 +723924 Mir218-2 MGI:MGI:3618752|Ensembl:ENSMUSG00000065583|miRBase:MI0000701 +723925 Mir106b MGI:MGI:3619060|Ensembl:ENSMUSG00000065514|miRBase:MI0000407 +723926 Mir25 MGI:MGI:3619266|Ensembl:ENSMUSG00000065394|miRBase:MI0000689 +723927 Mir299a MGI:MGI:3619322|Ensembl:ENSMUSG00000106653|miRBase:MI0000399 +723928 Mir302d MGI:MGI:3619328|Ensembl:ENSMUSG00000065447|miRBase:MI0003718 +723929 Mir325 MGI:MGI:3619336|Ensembl:ENSMUSG00000065425|miRBase:MI0000597 +723930 Mir335 MGI:MGI:3619348|Ensembl:ENSMUSG00000065501|miRBase:MI0000817 +723931 Mir344 MGI:MGI:3619359|Ensembl:ENSMUSG00000065568|miRBase:MI0000630 +723932 Mir34c MGI:MGI:3619365|Ensembl:ENSMUSG00000065587|miRBase:MI0000403 +723933 Mir369 MGI:MGI:3619374|Ensembl:ENSMUSG00000065561|miRBase:MI0003535 +723934 Mir376b MGI:MGI:3619378|Ensembl:ENSMUSG00000105853|miRBase:MI0001162 +723935 Mir381 MGI:MGI:3619391|Ensembl:ENSMUSG00000098838|miRBase:MI0000798 +723936 Mir411 MGI:MGI:3619399|Ensembl:ENSMUSG00000065477|miRBase:MI0001163 +723937 Mir433 MGI:MGI:3619404|Ensembl:ENSMUSG00000070072|miRBase:MI0001525 +723938 Mir450-2 MGI:MGI:3619411|Ensembl:ENSMUSG00000076399|miRBase:MI0003537 +723939 Mir471 MGI:MGI:3619419|Ensembl:ENSMUSG00000070104|miRBase:MI0002406 +723940 Mir487b MGI:MGI:3619424|Ensembl:ENSMUSG00000076219|miRBase:MI0003534 +723941 Mir541 MGI:MGI:3619430|Ensembl:ENSMUSG00000076052|miRBase:MI0003521 +723942 Mir92-2 MGI:MGI:3619438|Ensembl:ENSMUSG00000065613|miRBase:MI0000580 +723944 Mir200c MGI:MGI:3618750|Ensembl:ENSMUSG00000065462|miRBase:MI0000694 +723945 Mir297a-2 MGI:MGI:5453891|Ensembl:ENSMUSG00000076983|miRBase:MI0000397 +723946 Mir345 MGI:MGI:3619361|Ensembl:ENSMUSG00000065429|miRBase:MI0000632 +723947 Mir98 MGI:MGI:3619441|Ensembl:ENSMUSG00000065536|miRBase:MI0000586 +723948 Mir302b MGI:MGI:3619326|Ensembl:ENSMUSG00000076252|miRBase:MI0003716 +723949 Mir16-2 MGI:MGI:3618690|Ensembl:ENSMUSG00000065606|miRBase:MI0000566 +723950 Mir124a-2 MGI:MGI:3618700|Ensembl:ENSMUSG00000093073|miRBase:MI0000717 +723951 Mir124a-3 MGI:MGI:3618704|Ensembl:ENSMUSG00000065454|miRBase:MI0000150 +723952 Mir125b-2 MGI:MGI:3618706|Ensembl:ENSMUSG00000065472|miRBase:MI0000152 +723953 Mir129-2 MGI:MGI:3618711|Ensembl:ENSMUSG00000065511|miRBase:MI0000585 +723954 Mir133a-2 MGI:MGI:3618718|Ensembl:ENSMUSG00000065460|miRBase:MI0000820 +723955 Mir135a-2 MGI:MGI:3618729|Ensembl:ENSMUSG00000065524|miRBase:MI0000715 +723956 Mir138-2 MGI:MGI:3618733|Ensembl:ENSMUSG00000065512|miRBase:MI0000164 +723957 Mir194-2 MGI:MGI:3618738|Ensembl:ENSMUSG00000065582|miRBase:MI0000733 +723958 Mir196a-2 MGI:MGI:3618739|Ensembl:ENSMUSG00000065488|miRBase:MI0000553 +723959 Mir1a-2 MGI:MGI:3618746|Ensembl:ENSMUSG00000106348|miRBase:MI0000652 +723960 Mir24-2 MGI:MGI:3618755|Ensembl:ENSMUSG00000065541|miRBase:MI0000572 +723962 Mir26a-2 MGI:MGI:3619045|Ensembl:ENSMUSG00000065430|miRBase:MI0000706 +723963 Mir29b-2 MGI:MGI:3619047|Ensembl:ENSMUSG00000065412|miRBase:MI0000712 +723964 Mir30c-2 MGI:MGI:3619048|Ensembl:ENSMUSG00000065567|miRBase:MI0000548 +723965 Mirlet7a-2 MGI:MGI:3619049|Ensembl:ENSMUSG00000092770|miRBase:MI0000557 +723966 Mirlet7c-2 MGI:MGI:3619050|Ensembl:ENSMUSG00000065608|miRBase:MI0000560 +723967 Mir9-2 MGI:MGI:3619442|Ensembl:ENSMUSG00000065424|miRBase:MI0000157 +723968 Mir9-3 MGI:MGI:3619443|Ensembl:ENSMUSG00000093238|miRBase:MI0000721 +723974 Mir500 MGI:MGI:3624341|Ensembl:ENSMUSG00000070108|miRBase:MI0004702 +723975 Mir721 MGI:MGI:3624349|Ensembl:ENSMUSG00000106479|miRBase:MI0004708 +723976 Mir652 MGI:MGI:3624350|Ensembl:ENSMUSG00000076011|miRBase:MI0004965 +723991 Igkv4-52 IMGT/GENE-DB:IGKV4-52 +723992 Gm9728 MGI:MGI:3780132 +723993 Gm9729 MGI:MGI:3780133 +724020 Klrb1-ps1 MGI:MGI:3624540 +724035 Igkv20-101-2 MGI:MGI:5009884|IMGT/GENE-DB:IGKV20-101-2 +724062 Mir101b MGI:MGI:3618696|Ensembl:ENSMUSG00000065556|miRBase:MI0000649 +724063 Mir330 MGI:MGI:3619345|Ensembl:ENSMUSG00000065543|miRBase:MI0000607 +724064 Mir148b MGI:MGI:3618734|Ensembl:ENSMUSG00000065560|miRBase:MI0000617 +724106 Igkv13-57-2 MGI:MGI:5009885|IMGT/GENE-DB:IGKV13-57-2 +724112 BC106175 MGI:MGI:3628444 +727711 Gm15459 MGI:MGI:3705702 +727720 Defa-ps1 MGI:MGI:3630392|Ensembl:ENSMUSG00000095813 +732481 Gm9730 MGI:MGI:3780134 +732482 Gm9731 MGI:MGI:3780135 +732489 Mir674 MGI:MGI:3629631|Ensembl:ENSMUSG00000076376|miRBase:MI0004611 +732519 Gt(pU21)11Imeg MGI:MGI:3629687 +732520 Gt(pU21)138Imeg MGI:MGI:3629706 +732521 Gt(pU21)140Imeg MGI:MGI:3629719 +732522 Gt(pU21)40Imeg MGI:MGI:3629755 +732523 Gt(pU21)129Imeg MGI:MGI:3629774 +732524 Gt(pU21)51Imeg MGI:MGI:3629718 +732525 Gt(pU21)111Imeg MGI:MGI:3629765 +732526 Gt(pU21)27Imeg MGI:MGI:3629692 +732527 Gt(pU21)108Imeg MGI:MGI:3629711 +732528 Gt(pU21)39Imeg MGI:MGI:3629723 +732529 Gt(pU21)107Imeg MGI:MGI:3629729 +732530 Gt(pU21)105Imeg MGI:MGI:3629769 +732531 Gt(pU21)B129Imeg MGI:MGI:3639048 +732532 Gt(pU21)8Imeg MGI:MGI:3639327 +732533 Gt(pU21)103Imeg MGI:MGI:3629721 +732534 Gt(pU21)77Imeg MGI:MGI:3629694 +732535 Gt(pU21)115Imeg MGI:MGI:3629726 +732536 Gt(pU21B)113Imeg MGI:MGI:3629776 +732537 Gt(pU21)50Imeg MGI:MGI:3629696 +735252 Mir181a-1 MGI:MGI:3629589|Ensembl:ENSMUSG00000065565|miRBase:MI0000697 +735253 Mir488 MGI:MGI:3629597|Ensembl:ENSMUSG00000070103|miRBase:MI0004633 +735255 Mir669b MGI:MGI:3629607|Ensembl:ENSMUSG00000076126|miRBase:MI0004666 +735256 Mir669a-1 MGI:MGI:3629611|Ensembl:ENSMUSG00000096583|miRBase:MI0004523 +735257 Mir467b MGI:MGI:3629617|Ensembl:ENSMUSG00000095509|miRBase:MI0004671 +735258 Mir669a-2 MGI:MGI:3629622|Ensembl:ENSMUSG00000076014|miRBase:MI0004667 +735259 Mir670 MGI:MGI:3629629|Ensembl:ENSMUSG00000076335|miRBase:MI0004295 +735261 Mir684-2 MGI:MGI:3629642|Ensembl:ENSMUSG00000105333|miRBase:MI0004648 +735262 Mir455 MGI:MGI:3629649|Ensembl:ENSMUSG00000070102|miRBase:MI0004679 +735263 Mir698 MGI:MGI:3629653|Ensembl:ENSMUSG00000076119|miRBase:MI0004682 +735264 Mir671 MGI:MGI:3629656|Ensembl:ENSMUSG00000076387|miRBase:MI0004133 +735265 Mir703 MGI:MGI:3629657|Ensembl:ENSMUSG00000105814|miRBase:MI0004687 +735266 Mir592 MGI:MGI:3629661|Ensembl:ENSMUSG00000076067|miRBase:MI0004127 +735267 Mir705 MGI:MGI:3629673|Ensembl:ENSMUSG00000076012|miRBase:MI0004689 +735268 Mir680-1 MGI:MGI:3629682|Ensembl:ENSMUSG00000076212|miRBase:MI0004640 +735269 Mir707 MGI:MGI:3629685|Ensembl:ENSMUSG00000076051|miRBase:MI0004691 +735270 Mir710 MGI:MGI:3629713|Ensembl:ENSMUSG00000076042|miRBase:MI0004694 +735271 Mir709 MGI:MGI:3629717|Ensembl:ENSMUSG00000076144|miRBase:MI0004693 +735272 Mir669a-3 MGI:MGI:3629609|Ensembl:ENSMUSG00000076028|miRBase:MI0004668 +735273 Mir669c MGI:MGI:3629619|Ensembl:ENSMUSG00000076118|miRBase:MI0004673 +735274 Mir684-1 MGI:MGI:3629628|Ensembl:ENSMUSG00000106252|miRBase:MI0004647 +735275 Mir499 MGI:MGI:3629633|Ensembl:ENSMUSG00000076312|miRBase:MI0004676 +735277 Mir697 MGI:MGI:3629652|Ensembl:ENSMUSG00000076271|miRBase:MI0004681 +735278 Mir701 MGI:MGI:3629658|Ensembl:ENSMUSG00000076163|miRBase:MI0004685 +735279 Mir490 MGI:MGI:3629662|Ensembl:ENSMUSG00000070075|miRBase:MI0005002 +735280 Mir675 MGI:MGI:3629709|Ensembl:ENSMUSG00000076275|miRBase:MI0004123 +735281 Mir297b MGI:MGI:3629625|Ensembl:ENSMUSG00000076222|miRBase:MI0004674 +735282 Mir491 MGI:MGI:3629651|Ensembl:ENSMUSG00000070077|miRBase:MI0004680 +735283 Mir702 MGI:MGI:3629659|Ensembl:ENSMUSG00000076240|miRBase:MI0004686 +735284 Mir708 MGI:MGI:3629686|Ensembl:ENSMUSG00000076143|miRBase:MI0004692 +735285 Mir700 MGI:MGI:3629655|Ensembl:ENSMUSG00000076123|miRBase:MI0004684 +735286 Mir467a-1 MGI:MGI:3629612|Ensembl:ENSMUSG00000096624|miRBase:MI0002402 +735287 Mir695 MGI:MGI:3629632|Ensembl:ENSMUSG00000076216|miRBase:MI0004675 +735288 Mir692-2 MGI:MGI:3629654|Ensembl:ENSMUSG00000094403|miRBase:MI0004661 +735289 Mir704 MGI:MGI:3629672|Ensembl:ENSMUSG00000076060|miRBase:MI0004688 +735290 Mir706 MGI:MGI:3629678|Ensembl:ENSMUSG00000076217|miRBase:MI0004690 +735298 LOC735298 - +735308 Mir216b MGI:MGI:3640613|Ensembl:ENSMUSG00000076318|miRBase:MI0004126 +735309 Mir449c MGI:MGI:3639505|Ensembl:ENSMUSG00000076146|miRBase:MI0004645 +751518 Mir677 MGI:MGI:3629885|Ensembl:ENSMUSG00000093245|Ensembl:ENSMUSG00000104755|miRBase:MI0004634 +751519 Mir423 MGI:MGI:3629888|Ensembl:ENSMUSG00000065518|miRBase:MI0004637 +751520 Mir680-3 MGI:MGI:3629889|Ensembl:ENSMUSG00000076253|miRBase:MI0004642 +751521 Mir666 MGI:MGI:3629901|Ensembl:ENSMUSG00000076272|miRBase:MI0004553 +751522 Mir495 MGI:MGI:3629903|Ensembl:ENSMUSG00000070105|miRBase:MI0004639 +751523 Mir668 MGI:MGI:3629905|Ensembl:ENSMUSG00000099236|miRBase:MI0004134 +751524 Mir496a MGI:MGI:3629907|Ensembl:ENSMUSG00000070136|miRBase:MI0004589 +751525 Mir686 MGI:MGI:3629913|Ensembl:ENSMUSG00000076128|miRBase:MI0004650 +751526 Mir719 MGI:MGI:3629914|Ensembl:ENSMUSG00000076270|miRBase:MI0004651 +751527 Mir19b-1 MGI:MGI:3629917|Ensembl:ENSMUSG00000076256|miRBase:MI0000718 +751529 Mir692-1 MGI:MGI:3629930|Ensembl:ENSMUSG00000076218|miRBase:MI0004660 +751531 Mir717 MGI:MGI:3629951|Ensembl:ENSMUSG00000076214|miRBase:MI0004704 +751532 Mir450b MGI:MGI:3629953|Ensembl:ENSMUSG00000076050|miRBase:MI0004705 +751533 Mir718 MGI:MGI:3629956|Ensembl:ENSMUSG00000076127|miRBase:MI0004707 +751534 Mir676 MGI:MGI:3629957|Ensembl:ENSMUSG00000076398|miRBase:MI0005003 +751535 Mir672 MGI:MGI:3629959|Ensembl:ENSMUSG00000076286|miRBase:MI0004258 +751536 Mir711 MGI:MGI:3629883|Ensembl:ENSMUSG00000076142|miRBase:MI0004695 +751537 Mir497 MGI:MGI:3629886|Ensembl:ENSMUSG00000105220|miRBase:MI0004636 +751538 Mir681 MGI:MGI:3629893|Ensembl:ENSMUSG00000076065|miRBase:MI0004643 +751539 Mir679 MGI:MGI:3629899|Ensembl:ENSMUSG00000076145|miRBase:MI0004638 +751541 Mir687 MGI:MGI:3629916|Ensembl:ENSMUSG00000076121|miRBase:MI0004652 +751542 Mir688 MGI:MGI:3629926|Ensembl:ENSMUSG00000076009|miRBase:MI0004653 +751543 Mir690 MGI:MGI:3629929|Ensembl:ENSMUSG00000076064|miRBase:MI0004658 +751544 Mir532 MGI:MGI:3629950|Ensembl:ENSMUSG00000070139|miRBase:MI0003206 +751545 Mir505 MGI:MGI:3629955|Ensembl:ENSMUSG00000070081|miRBase:MI0004706 +751546 Mir374b MGI:MGI:3629958|Ensembl:ENSMUSG00000076269|miRBase:MI0004125 +751547 Mir673 MGI:MGI:3629894|Ensembl:ENSMUSG00000076316|miRBase:MI0004601 +751548 Mir713 MGI:MGI:3629909|Ensembl:ENSMUSG00000096098|miRBase:MI0004698 +751549 Mir92-1 MGI:MGI:3629918|Ensembl:ENSMUSG00000076062|miRBase:MI0000719 +751550 Mir146b MGI:MGI:3629945|Ensembl:ENSMUSG00000070127|miRBase:MI0004665 +751551 Mir680-2 MGI:MGI:3629961|Ensembl:ENSMUSG00000076117|miRBase:MI0004641 +751552 Mir667 MGI:MGI:3629904|Ensembl:ENSMUSG00000076396|miRBase:MI0004196 +751553 Mir693 MGI:MGI:3629942|Ensembl:ENSMUSG00000076141|miRBase:MI0004662 +751554 Mir678 MGI:MGI:3629884|Ensembl:ENSMUSG00000076068|miRBase:MI0004635 +751555 Mir665 MGI:MGI:3629896|Ensembl:ENSMUSG00000076313|miRBase:MI0004171 +751556 Mir682 MGI:MGI:3629911|Ensembl:ENSMUSG00000076236|miRBase:MI0004644 +751557 Mir615 MGI:MGI:3629927|Ensembl:ENSMUSG00000076010|miRBase:MI0005004 +751558 Mir694 MGI:MGI:3629943|Ensembl:ENSMUSG00000076147|miRBase:MI0004664 +751559 Mir683-1 MGI:MGI:3629908|Ensembl:ENSMUSG00000095697|miRBase:MI0004646 +751560 Mir501 MGI:MGI:3629949|Ensembl:ENSMUSG00000076251|miRBase:MI0004703 +751561 Mir691 MGI:MGI:3639287|Ensembl:ENSMUSG00000104758|miRBase:MI0004659 +751864 Gm9733 MGI:MGI:3780136|Ensembl:ENSMUSG00000078783|Vega:OTTMUSG00000052296 +751865 Sap25 MGI:MGI:3802945|Ensembl:ENSMUSG00000079165|Vega:OTTMUSG00000040074 +751866 Kis2 MGI:MGI:3617487 +767812 AA474408 MGI:MGI:3034216 +767814 AU019990 MGI:MGI:3034641|Ensembl:ENSMUSG00000074783 +767815 BB557941 MGI:MGI:3034820|Ensembl:ENSMUSG00000084938 +768252 Foxl2os MGI:MGI:3614944|Ensembl:ENSMUSG00000097072 +768253 LOC768253 - +768271 BE949265 MGI:MGI:3528150 +768332 C030029H13Rik MGI:MGI:3665284 +777602 AW742323 MGI:MGI:2687287 +777648 Ighj1 MGI:MGI:4439802|IMGT/GENE-DB:IGHJ1 +777654 Ighj2 MGI:MGI:4439803|IMGT/GENE-DB:IGHJ2 +777655 Ighj3 MGI:MGI:4439767|IMGT/GENE-DB:IGHJ3 +777656 Ighj4 MGI:MGI:4439658|IMGT/GENE-DB:IGHJ4 +777657 Ighd1-1 MGI:MGI:4439871|IMGT/GENE-DB:IGHD1-1 +777658 Ighd1-2 IMGT/GENE-DB:IGHD1-2 +777659 Ighd2-1 IMGT/GENE-DB:IGHD2-1 +777660 Ighd2-10 IMGT/GENE-DB:IGHD2-10 +777661 Ighd4-1 MGI:MGI:4439801|IMGT/GENE-DB:IGHD4-1 +777662 Ighd3-2 MGI:MGI:4439707|IMGT/GENE-DB:IGHD3-2 +777663 Ighd5-6 MGI:MGI:4937234|IMGT/GENE-DB:IGHD5-6 +777664 Ighd2-8 MGI:MGI:4439706|IMGT/GENE-DB:IGHD2-8 +777665 Ighd5-5 MGI:MGI:4937334|IMGT/GENE-DB:IGHD5-5 +777667 Ighd2-7 MGI:MGI:4439866|IMGT/GENE-DB:IGHD2-7 +777669 Ighd5-8 MGI:MGI:4937171|IMGT/GENE-DB:IGHD5-8 +777670 Ighd5-4 MGI:MGI:4937058|IMGT/GENE-DB:IGHD5-4 +777672 Ighd2-6 MGI:MGI:4439865|IMGT/GENE-DB:IGHD2-6 +777673 Ighd5-7 MGI:MGI:4936973|IMGT/GENE-DB:IGHD5-7 +777674 Ighd5-3 MGI:MGI:4937297|IMGT/GENE-DB:IGHD5-3 +777675 Ighd2-5 MGI:MGI:4439705|IMGT/GENE-DB:IGHD2-5 +777676 Ighd5-2 MGI:MGI:4936898|IMGT/GENE-DB:IGHD5-2 +777677 Ighd2-4 MGI:MGI:4439709|IMGT/GENE-DB:IGHD2-4 +777678 Ighd6-2 MGI:MGI:4937120|IMGT/GENE-DB:IGHD6-2 +777679 Ighd2-3 MGI:MGI:4439708|IMGT/GENE-DB:IGHD2-3 +777680 Ighd6-1 MGI:MGI:4937254|IMGT/GENE-DB:IGHD6-1 +777681 Ighd3-1 MGI:MGI:4439891|IMGT/GENE-DB:IGHD3-1 +777682 Ighd5-1 MGI:MGI:4937117|IMGT/GENE-DB:IGHD5-1 +777683 Ighv5-1 MGI:MGI:5009886|IMGT/GENE-DB:IGHV5-1 +777684 Ighv2-1 MGI:MGI:4936981|IMGT/GENE-DB:IGKV2-1 +777685 Ighv5-2 MGI:MGI:4439893|IMGT/GENE-DB:IGHV5-2 +777686 Ighv2-2 MGI:MGI:4439894|IMGT/GENE-DB:IGHV2-2 +777687 Ighv5-3 MGI:MGI:5009887|IMGT/GENE-DB:IGHV5-3 +777688 Ighv5-4 MGI:MGI:4439895|IMGT/GENE-DB:IGHV5-4 +777689 Ighv6-1 MGI:MGI:5009888|IMGT/GENE-DB:IGHV6-1 +777779 Ighv5-5 MGI:MGI:5009889|IMGT/GENE-DB:IGHV5-5 +777780 Ighv5-6 MGI:MGI:4439815|IMGT/GENE-DB:IGHV5-6 +777781 Ighv5-7 MGI:MGI:3642590|IMGT/GENE-DB:IGHV5-7 +777782 Ighv5-8 MGI:MGI:5009890|IMGT/GENE-DB:IGHV5-8 +777783 Ighv5-10 MGI:MGI:3642589|IMGT/GENE-DB:IGHV5-10 +777784 Ighv5-11 MGI:MGI:5009891|IMGT/GENE-DB:IGHV5-11 +780792 Ighv5-15 MGI:MGI:4439812|IMGT/GENE-DB:IGHV5-15 +780793 Ighv2-7 MGI:MGI:4439521|IMGT/GENE-DB:IGHV2-7 +780794 Ighv5-17 MGI:MGI:4439533|IMGT/GENE-DB:IGHV5-17 +780796 Ighv5-18 MGI:MGI:5009892|IMGT/GENE-DB:IGHV5-18 +780797 Ighv2-8 MGI:MGI:5009893|IMGT/GENE-DB:IGHV2-8 +780798 Ighv5-19 MGI:MGI:5009894|IMGT/GENE-DB:IGHV5-19 +780799 Ighv7-1 MGI:MGI:4439622|IMGT/GENE-DB:IGHV7-1 +780800 Ighv7-2 MGI:MGI:4439623|IMGT/GENE-DB:IGHV7-2 +780801 Ighv14-1 MGI:MGI:4439920|IMGT/GENE-DB:IGHV14-1 +780802 Ighv4-1 MGI:MGI:4439536|IMGT/GENE-DB:IGHV4-1 +780803 Ighv3-1 MGI:MGI:4439534|IMGT/GENE-DB:IGHV3-1 +780804 Ighv11-1 MGI:MGI:4439535|IMGT/GENE-DB:IGHV11-1 +780817 Ighv3-2 MGI:MGI:4439923|IMGT/GENE-DB:IGHV3-2 +780818 Ighv11-2 MGI:MGI:4947968|IMGT/GENE-DB:IGHV11-2 +780822 Ighv6-2 MGI:MGI:5009895|IMGT/GENE-DB:IGHV6-2 +780823 Ighv12-1 MGI:MGI:5295669|IMGT/GENE-DB:IGHV12-1 +780824 Ighv12-2 MGI:MGI:5009896|IMGT/GENE-DB:IGHV12-2 +780825 Ighv9-3 MGI:MGI:3642720|IMGT/GENE-DB:IGHV9-3 +780827 Ighv15-1 MGI:MGI:5009897|IMGT/GENE-DB:IGHV15-1 +780828 Ighv13-1 MGI:MGI:4439855|IMGT/GENE-DB:IGHV13-1 +780829 Ighv3-6 MGI:MGI:4439856|IMGT/GENE-DB:IGHV3-6 +780830 Ighv3-7 MGI:MGI:5009898|IMGT/GENE-DB:IGHV3-7 +780831 Ighv3-8 MGI:MGI:3645298|IMGT/GENE-DB:IGHV3-8 +780832 Ighv5-21 MGI:MGI:5009899|IMGT/GENE-DB:IGHV5-21 +780833 Ighv8-1 MGI:MGI:5009900|IMGT/GENE-DB:IGHV8-1 +780834 Ighv1-1 MGI:MGI:5009901|IMGT/GENE-DB:IGHV1-1 +780859 Ighv1-3 MGI:MGI:5009902|IMGT/GENE-DB:IGHV1-3 +780860 Ighv10-2 MGI:MGI:5009903|IMGT/GENE-DB:IGHV10-2 +780861 Ighv1-6 MGI:MGI:5009904|IMGT/GENE-DB:IGHV1-6 +780862 Ighv10-4 MGI:MGI:5009905|IMGT/GENE-DB:IGHV10-4 +780863 Ighv1-8 MGI:MGI:5009906|IMGT/GENE-DB:IGHV1-8 +780864 Ighv15-2 MGI:MGI:4947963|IMGT/GENE-DB:IGHV15-2 +780865 Ighv1-13 MGI:MGI:5009907|IMGT/GENE-DB:IGHV1-13 +780883 Ighv1-22 MGI:MGI:4439784|IMGT/GENE-DB:IGHV1-22 +780884 Ighv1-23 MGI:MGI:3815050|IMGT/GENE-DB:IGHV1-23 +780885 Ighv1-24 MGI:MGI:3815052|IMGT/GENE-DB:IGHV1-24 +780886 Ighv1-27 MGI:MGI:5009908|IMGT/GENE-DB:IGHV1-27 +780887 Ighv1-29 MGI:MGI:5009909|IMGT/GENE-DB:IGHV1-29 +780888 Ighv1-32 MGI:MGI:5009910|IMGT/GENE-DB:IGHV1-32 +780890 Ighv1-38 MGI:MGI:5009911|IMGT/GENE-DB:IGHV1-38 +780891 Ighv1-39 MGI:MGI:4439888|IMGT/GENE-DB:IGHV1-39 +780892 Ighv1-40 MGI:MGI:5009912|IMGT/GENE-DB:IGHV1-40 +780894 Ighv1-45 MGI:MGI:5009913|IMGT/GENE-DB:IGHV1-45 +780926 Ighv1-17-1 MGI:MGI:5009914|IMGT/GENE-DB:IGHV1-17-1 +780927 Ighv8-3 MGI:MGI:5009915|IMGT/GENE-DB:IGHV8-3 +780928 Ighv1-48 MGI:MGI:5009916|IMGT/GENE-DB:IGHV1-48 +780929 Ighv1-50 MGI:MGI:4439753|IMGT/GENE-DB:IGHV1-50 +780930 Ighv1-51 MGI:MGI:5009917|IMGT/GENE-DB:IGHV1-51 +780931 Ighv1-53 MGI:MGI:3576502|IMGT/GENE-DB:IGHV1-53 +780932 Ighv1-55 MGI:MGI:4439716|IMGT/GENE-DB:IGHV1-55 +780936 Ighv8-7 MGI:MGI:5009918|IMGT/GENE-DB:IGHV8-7 +780937 Ighv1-57 MGI:MGI:5009919|IMGT/GENE-DB:IGHV1-57 +780938 Ighv8-8 MGI:MGI:3815333|IMGT/GENE-DB:IGHV8-8 +780939 Ighv1-58 MGI:MGI:4439557|IMGT/GENE-DB:IGHV1-58 +780940 Ighv1-60 MGI:MGI:5009920|IMGT/GENE-DB:IGHV1-60 +780956 Ighv1-63 MGI:MGI:3642755|IMGT/GENE-DB:IGHV1-63 +780957 Ighv8-10 MGI:MGI:5009921|IMGT/GENE-DB:IGHV8-10 +780958 Ighv1-65 MGI:MGI:5009922|IMGT/GENE-DB:IGHV1-65 +780959 Ighv1-68 MGI:MGI:5009923|IMGT/GENE-DB:IGHV1-68 +780960 Ighv8-12 MGI:MGI:3642873|IMGT/GENE-DB:IGHV8-12 +790900 Ighv5-13 MGI:MGI:5009924|IMGT/GENE-DB:IGHV5-13 +790909 Gm11186 MGI:MGI:3649729|Ensembl:ENSMUSG00000087668 +790910 Gm11201 MGI:MGI:3649951 +790911 Slc13a2os MGI:MGI:3649278|Ensembl:ENSMUSG00000085747 +790912 Rab11fip4os1 MGI:MGI:3650027|Ensembl:ENSMUSG00000087434 +790913 Gm11413 MGI:MGI:3650701|Ensembl:ENSMUSG00000086321 +790956 Rs5-8s1 - +791069 Mir301b MGI:MGI:3691602|Ensembl:ENSMUSG00000076288|miRBase:MI0004122 +791070 Mir744 MGI:MGI:3691603|Ensembl:ENSMUSG00000076460|miRBase:MI0004124 +791071 Mir758 MGI:MGI:3691604|Ensembl:ENSMUSG00000076459|miRBase:MI0004129 +791072 Mir551b MGI:MGI:3691605|Ensembl:ENSMUSG00000076120|miRBase:MI0004131 +791073 Mir762 MGI:MGI:3691607|Ensembl:ENSMUSG00000076454|miRBase:MI0004215 +791074 Mir802 MGI:MGI:3691608|Ensembl:ENSMUSG00000076457|miRBase:MI0004249 +791075 Mir761 MGI:MGI:3691609|Ensembl:ENSMUSG00000076444|miRBase:MI0004306 +791076 Mir763 MGI:MGI:3691611|Ensembl:ENSMUSG00000076448|miRBase:MI0004516 +791077 Mir760 MGI:MGI:3691613|Ensembl:ENSMUSG00000076456|miRBase:MI0004605 +791079 Mir770 MGI:MGI:3691606|Ensembl:ENSMUSG00000076451|miRBase:MI0004203 +791080 Mir759 MGI:MGI:3691612|Ensembl:ENSMUSG00000076453|miRBase:MI0004554 +791081 Mir764 MGI:MGI:3691610|Ensembl:ENSMUSG00000076458|miRBase:MI0004310 +791083 Gm9742 MGI:MGI:3780137 +791088 Tmem147os MGI:MGI:3642392 +791089 Ighv2-9-1 MGI:MGI:4439519|IMGT/GENE-DB:IGHV2-9-1 +791090 Ighv2-6-8 MGI:MGI:4439811|IMGT/GENE-DB:IGHV2-6-8 +791118 9330160F10Rik MGI:MGI:3693095 +791260 Tomt MGI:MGI:3769724|Ensembl:ENSMUSG00000078630|Vega:OTTMUSG00000025104 +791262 Gm9912 MGI:MGI:3641631 +791265 Gm9984 MGI:MGI:3641639 +791266 Gm9945 MGI:MGI:3641652 +791267 Gm16488 MGI:MGI:3641664 +791270 Gm10115 MGI:MGI:3641675 +791271 Gm9981 MGI:MGI:3641676 +791272 Gm10091 MGI:MGI:3641677 +791273 B630006N21Rik MGI:MGI:3641697 +791274 AY512949 MGI:MGI:3641719 +791275 Gm9885 MGI:MGI:3641726 +791276 A930039A15Rik MGI:MGI:3641728 +791278 Gm16495 MGI:MGI:3641737 +791280 Gm9993 MGI:MGI:3641793 +791281 Gm10253 MGI:MGI:3641796 +791282 Gm10030 MGI:MGI:3641798|Ensembl:ENSMUSG00000057802 +791283 Gm9978 MGI:MGI:3641806 +791284 Gm10152 MGI:MGI:3641809 +791285 Gm16487 MGI:MGI:3641811 +791286 Gm9886 MGI:MGI:3641826 +791287 Gm9951 MGI:MGI:3641827 +791288 Gm9881 MGI:MGI:3641832|Ensembl:ENSMUSG00000052471 +791290 Gm9938 MGI:MGI:3641836 +791292 Gm9936 MGI:MGI:3641854|Ensembl:ENSMUSG00000107108 +791293 Gm9948 MGI:MGI:3641860 +791294 Gm9958 MGI:MGI:3641866|Ensembl:ENSMUSG00000054945 +791295 C030005K15Rik MGI:MGI:3641867 +791297 Gm9966 MGI:MGI:3641871 +791298 Gm9956 MGI:MGI:3641872 +791299 Gm10069 MGI:MGI:3641875|Ensembl:ENSMUSG00000059659 +791300 Gm9752 MGI:MGI:3641896 +791301 Gm10265 MGI:MGI:3641897 +791303 Gm10277 MGI:MGI:3641921 +791304 Gm15352 MGI:MGI:3641922 +791305 B430202K04Rik MGI:MGI:3641923 +791306 Gm9915 MGI:MGI:3641924 +791307 Gm10248 MGI:MGI:3641931|Ensembl:ENSMUSG00000068680 +791308 Gm9933 MGI:MGI:3641937 +791309 Gm9919 MGI:MGI:3641953 +791310 Gm10158 MGI:MGI:3641965 +791311 Gm1000 MGI:MGI:3641968 +791312 Gm9997 MGI:MGI:3641988 +791314 Gm9874 MGI:MGI:3642006 +791315 Gm9875 MGI:MGI:3642007 +791316 Gm9891 MGI:MGI:3642023 +791317 Gm9921 MGI:MGI:3642033 +791318 Gm10125 MGI:MGI:3642044|Ensembl:ENSMUSG00000063087 +791319 Gm9831 MGI:MGI:3642047 +791320 Gm9937 MGI:MGI:3642051 +791322 Gm9876 MGI:MGI:3642095 +791323 Gm9954 MGI:MGI:3642120 +791324 Gm9799 MGI:MGI:3642121 +791325 Gm9902 MGI:MGI:3642122 +791326 Gm9922 MGI:MGI:3642123 +791328 D630011A20Rik MGI:MGI:3642132 +791329 Gm9968 MGI:MGI:3642146 +791330 A230060F14Rik MGI:MGI:3642156 +791332 B930095I24Rik MGI:MGI:3642172 +791333 Gm10050 MGI:MGI:3642189 +791335 Gm9914 MGI:MGI:3642208 +791336 Gm9924 MGI:MGI:3642216 +791338 Gm10190 MGI:MGI:3642237 +791339 Gm15155 MGI:MGI:3642241 +791340 Gm10006 MGI:MGI:3642256 +791341 Gm9990 MGI:MGI:3642272 +791342 Gm10097 MGI:MGI:3642295 +791343 Gm9905 MGI:MGI:3642311 +791344 E330037I15Rik MGI:MGI:3642333 +791345 Gm9960 MGI:MGI:3642336 +791346 Gm10118 MGI:MGI:3642340 +791347 Gm10007 MGI:MGI:3642351 +791350 Gm9898 MGI:MGI:3642391 +791351 C630004M23Rik MGI:MGI:3642399 +791352 Gm9930 MGI:MGI:3642400 +791353 Gm9931 MGI:MGI:3642402 +791354 Gm9873 MGI:MGI:3642403 +791355 Arf4os MGI:MGI:3642411 +791356 Gm9944 MGI:MGI:3642412 +791357 Gm9982 MGI:MGI:3642428 +791358 Gm10065 MGI:MGI:3642433 +791359 Gm9961 MGI:MGI:3642444|Ensembl:ENSMUSG00000055015|Vega:OTTMUSG00000027427 +791361 Gm16497 MGI:MGI:3642481|Ensembl:ENSMUSG00000113336 +791362 C130032M10Rik MGI:MGI:3642482 +791363 A730071L15Rik MGI:MGI:3642498 +791364 Hottip MGI:MGI:3642509|Ensembl:ENSMUSG00000055408 +791366 Gm9973 MGI:MGI:3642527 +791367 Gm10099 MGI:MGI:3642539 +791368 Gm9996 MGI:MGI:3642549 +791369 Gm9889 MGI:MGI:3642568 +791370 A130051J06Rik MGI:MGI:3642574 +791371 Gm9910 MGI:MGI:3642577 +791373 B930078G14Rik MGI:MGI:3642584 +791374 Gm9860 MGI:MGI:3642591 +791375 Gm9932 MGI:MGI:3642594 +791376 Gm9964 MGI:MGI:3642605 +791377 Gm9916 MGI:MGI:3642633 +791378 Gm10280 MGI:MGI:3642651|Ensembl:ENSMUSG00000110541 +791379 C030009H01Rik MGI:MGI:3642657 +791381 Gm15413 MGI:MGI:3642665|Ensembl:ENSMUSG00000053049 +791382 Gm9753 MGI:MGI:3642671 +791383 Gm9962 MGI:MGI:3642695|Ensembl:ENSMUSG00000055048 +791385 Gm10276 MGI:MGI:3642699 +791386 Gm10113 MGI:MGI:3642714 +791387 Gm9869 MGI:MGI:3642719 +791389 Gm9867 MGI:MGI:3642724 +791390 Gm16498 MGI:MGI:3642729 +791391 Gm10165 MGI:MGI:3642736 +791392 Gm9947 MGI:MGI:3642739 +791393 A230065N10Rik MGI:MGI:3642744 +791394 Gm9878 MGI:MGI:3642745 +791395 D330020A13Rik MGI:MGI:3642762 +791396 Gm16485 MGI:MGI:3642771 +791397 Gm9972 MGI:MGI:3642779 +791399 Gm9884 MGI:MGI:3642830 +791400 B430203G13Rik MGI:MGI:3642832 +791402 9230104M06Rik MGI:MGI:3642845 +791403 Mhrt MGI:MGI:3642848|Ensembl:ENSMUSG00000097652 +791404 6530402D11Rik MGI:MGI:3642877 +791405 Gm10002 MGI:MGI:3642882 +791406 Gm9979 MGI:MGI:3642885 +791407 Gm10032 MGI:MGI:3642901 +791408 Gm16496 MGI:MGI:3642912 +791409 Gm9883 MGI:MGI:3642922 +791411 Gm13199 MGI:MGI:3649231 +791413 Gm12592 MGI:MGI:3649892 +791415 Gm12500 MGI:MGI:3650304|Ensembl:ENSMUSG00000056411 +791417 Gm14164 MGI:MGI:3650730|Ensembl:ENSMUSG00000068062 +791419 Gm12511 MGI:MGI:3651363 +791420 Gm11232 MGI:MGI:3651439 +791421 Gm14168 MGI:MGI:3651463 +791422 Gm11426 MGI:MGI:3651541|Ensembl:ENSMUSG00000069796 +791423 Gm11190 MGI:MGI:3651694|Ensembl:ENSMUSG00000055045 +100008564 Gm14018 MGI:MGI:3649456 +100008567 Gm14964 MGI:MGI:3641621 +100009600 Zglp1 MGI:MGI:3696042|Ensembl:ENSMUSG00000079681|Vega:OTTMUSG00000063265 +100009609 Vmn2r65 MGI:MGI:3642776|Ensembl:ENSMUSG00000066372|Vega:OTTMUSG00000037868 +100009614 Gm10024 MGI:MGI:3641784|Ensembl:ENSMUSG00000094012 +100009664 F630206G17Rik MGI:MGI:3665471 +100009698 Gm14504 MGI:MGI:3705735 +100015211 Notumos MGI:MGI:3698431 +100033452 Gm13394 MGI:MGI:3651848 +100033459 Ifi208 MGI:MGI:2442822|Ensembl:ENSMUSG00000066677|Vega:OTTMUSG00000033992 +100034251 Wfdc17 MGI:MGI:3649773|Ensembl:ENSMUSG00000069792|Vega:OTTMUSG00000000971 +100034360 9330171B17Rik MGI:MGI:3696417 +100034361 Mfap1b MGI:MGI:3694697|Ensembl:ENSMUSG00000048222|Vega:OTTMUSG00000030519 +100034363 Tmsb15b2 MGI:MGI:3843061|Ensembl:ENSMUSG00000089996|Vega:OTTMUSG00000034850 +100034661 Gm12802 MGI:MGI:3649683 +100034662 Gm1969 MGI:MGI:3780138 +100034673 E430020m11rik - +100034675 Gm11335 MGI:MGI:3705194|Ensembl:ENSMUSG00000085016 +100034684 BC100530 MGI:MGI:3696883|Ensembl:ENSMUSG00000071561|Vega:OTTMUSG00000026985 +100034724 Rpl15-ps3 MGI:MGI:3782952 +100034726 Gm15772 MGI:MGI:3805541|Ensembl:ENSMUSG00000062353 +100034727 Rps12-ps3 MGI:MGI:3704503 +100034728 Rps12-ps4 MGI:MGI:3780139 +100034729 Gm15114 MGI:MGI:3713330|Ensembl:ENSMUSG00000079395|Vega:OTTMUSG00000019010 +100034733 2610305J24Rik MGI:MGI:1919770 +100034739 Gm17762 MGI:MGI:5009925 +100034748 A930017K11Rik MGI:MGI:2442713|Ensembl:ENSMUSG00000025727|Vega:OTTMUSG00000033450 +100034757 Trmq1 MGI:MGI:1891076 +100034758 Bpq7 MGI:MGI:1891319 +100034759 Mom3 MGI:MGI:1891403 +100034760 Ses3 MGI:MGI:2137001 +100034761 Mnif2 MGI:MGI:2151778 +100034762 Kcal1 MGI:MGI:2151780 +100034763 Mnif3 MGI:MGI:2151835 +100034764 Cdcs9 MGI:MGI:2159144 +100034765 Hfib2 MGI:MGI:2181187 +100034766 Ssial2 MGI:MGI:2385532 +100034767 Gvhd4 MGI:MGI:2386605 +100034768 Tcsz2 MGI:MGI:2386689 +100034769 Tcsz3 MGI:MGI:2386690 +100034770 Tshp2 MGI:MGI:2386692 +100034771 Tshp9 MGI:MGI:2386699 +100034772 Tshp10 MGI:MGI:2386700 +100034773 Tshp12 MGI:MGI:2386702 +100034774 Tshp15 MGI:MGI:2386707 +100034775 Tshp17 MGI:MGI:2386709 +100034776 Tshp18 MGI:MGI:2386710 +100034778 Paam2 MGI:MGI:2387303 +100034779 Sluc18 MGI:MGI:2387362 +100034780 Sluc25 MGI:MGI:2387370 +100034781 Kcal3 MGI:MGI:2387559 +100034782 Krcn1 MGI:MGI:2388805 +100034783 Nidds MGI:MGI:2388831 +100034784 Hrtfm2 MGI:MGI:2389058 +100034785 Bmd16 MGI:MGI:2389103 +100034786 Bwq5 MGI:MGI:2446729 +100034787 Bdln3 MGI:MGI:2446730 +100034788 Bdln4 MGI:MGI:2446731 +100034789 Bwq6 MGI:MGI:2446733 +100034790 Ath17 MGI:MGI:2447365 +100034791 Hdlq9 MGI:MGI:2448342 +100034792 Hdlq10 MGI:MGI:2448343 +100034793 Hdlq11 MGI:MGI:2448344 +100034794 Hdlq12 MGI:MGI:2448345 +100034795 Ath20 MGI:MGI:2451366 +100034796 Nctm2 MGI:MGI:2451368 +100034797 Chol6 MGI:MGI:2653461 +100034798 Chol8 MGI:MGI:2653464 +100034799 Chol9 MGI:MGI:2653465 +100034800 Hsm1 MGI:MGI:2653620 +100034801 Tgq1 MGI:MGI:2656141 +100034802 Obq16 MGI:MGI:2656142 +100034803 Obq17 MGI:MGI:2656143 +100034804 Lmr6 MGI:MGI:2656512 +100034805 Pgia18 MGI:MGI:2656520 +100034806 Pgia22 MGI:MGI:2656524 +100034807 Cia12 MGI:MGI:2656528 +100034808 Cia13 MGI:MGI:2656529 +100034809 Cia16 MGI:MGI:2656533 +100034810 Cia19 MGI:MGI:2656536 +100034811 Lmr12 MGI:MGI:2656545 +100034812 Lbm7 MGI:MGI:2656808 +100034813 Lbm8 MGI:MGI:2656809 +100034814 Lbm9 MGI:MGI:2656810 +100034815 Lgth6 MGI:MGI:2656817 +100034816 Lgth7 MGI:MGI:2656818 +100034817 Lgth8 MGI:MGI:2656819 +100034818 Musz2 MGI:MGI:2660613 +100034819 Musz3 MGI:MGI:2660614 +100034820 Musz5 MGI:MGI:2660617 +100034821 Pcd4ts2 MGI:MGI:2661279 +100034822 Circp2 MGI:MGI:2661439 +100034823 Cfbw1 MGI:MGI:2661703 +100034824 Cfld1 MGI:MGI:2661731 +100034825 Egrm3 MGI:MGI:2662762 +100034826 Ltq1 MGI:MGI:2662823 +100034827 Hrq3 MGI:MGI:2662844 +100034828 Sbmd1 MGI:MGI:2662975 +100034829 Sbmd3 MGI:MGI:2662977 +100034830 Mndl2 MGI:MGI:2663057 +100034831 Elpt MGI:MGI:2663452 +100034832 Tbrs4 MGI:MGI:2664009 +100034833 Vent2 MGI:MGI:2664091 +100034834 Psl3 MGI:MGI:2664118 +100034835 Radpf4 MGI:MGI:2664726 +100034836 Hypch MGI:MGI:2664783 +100034837 Ltsd3 MGI:MGI:2664840 +100034838 Ltsd8 MGI:MGI:2664845 +100034839 Tauph MGI:MGI:2664867 +100034840 Pcyts4 MGI:MGI:2665065 +100034841 Pcyts6 MGI:MGI:2665067 +100034842 Tbbmd2 MGI:MGI:2668915 +100034843 Tbbmd4 MGI:MGI:2668917 +100034844 Tbbmd7 MGI:MGI:2668920 +100034845 Fcsa2 MGI:MGI:2668936 +100034846 Loco2 MGI:MGI:2669259 +100034847 Ltry MGI:MGI:2669471 +100034848 Heal9 MGI:MGI:2669604 +100034849 Pcir2 MGI:MGI:2670125 +100034850 Pcir4 MGI:MGI:2670127 +100034851 Pcir5 MGI:MGI:2670128 +100034852 Iba5 MGI:MGI:2670345 +100034853 Alaa1 MGI:MGI:2670445 +100034854 Cfsw2 MGI:MGI:2670600 +100034855 Splrn2 MGI:MGI:2670603 +100034856 Cdav MGI:MGI:2670604 +100034857 Ofca3 MGI:MGI:2670607 +100034858 Fob3b1 MGI:MGI:2670913 +100034859 Pgia27 MGI:MGI:2675278 +100034860 Pgia28 MGI:MGI:2675279 +100034861 Rrodp1 MGI:MGI:2680094 +100034862 Rrodp2 MGI:MGI:2680095 +100034863 Capsq1 MGI:MGI:2680359 +100034864 Capsq3 MGI:MGI:2680361 +100034865 Aevm2 MGI:MGI:2680907 +100034866 Scc12 MGI:MGI:2680974 +100034867 Scc15 MGI:MGI:2680977 +100034868 Sgp3 MGI:MGI:2681652 +100034869 Pltpq1 MGI:MGI:2684018 +100034870 Nhdlq4 MGI:MGI:2686903 +100034871 Nhdlq5 MGI:MGI:2686904 +100034872 Nhdlq6 MGI:MGI:2686905 +100034873 Tgq2 MGI:MGI:2686908 +100034874 Obq19 MGI:MGI:2686912 +100034875 Hrtfm3 MGI:MGI:2686940 +100034876 Hrtfm5 MGI:MGI:2686942 +100034877 Hbnr6 MGI:MGI:2687240 +100034878 Hbnr8 MGI:MGI:2687242 +100034879 Abbp2 MGI:MGI:3026892 +100034880 Im5 MGI:MGI:3032858 +100034881 Nbwa1 MGI:MGI:3033344 +100034882 Diht MGI:MGI:3033372 +100034883 Lgth9 MGI:MGI:3035919 +100034884 Pbwg5 MGI:MGI:3035962 +100034885 Pbwg9 MGI:MGI:3035967 +100034886 Skmw1 MGI:MGI:3036182 +100034887 Skmw5 MGI:MGI:3036186 +100034888 Thcr MGI:MGI:3036489 +100034889 Vmbic4 MGI:MGI:3036602 +100034890 Vmbic7 MGI:MGI:3036605 +100034891 Vmbic8 MGI:MGI:3036606 +100034892 Lvic5 MGI:MGI:3036613 +100034893 Hdl6 MGI:MGI:3036903 +100034894 Alcw6 MGI:MGI:3037039 +100034895 Alcw7 MGI:MGI:3037040 +100034896 Moo3 MGI:MGI:3037102 +100034897 Cia5c MGI:MGI:3038267 +100034898 Imgt1 MGI:MGI:3038478 +100034899 Tchol1 MGI:MGI:3038481 +100034900 Nidd6k MGI:MGI:3038861 +100034901 Lp1 MGI:MGI:3039462 +100034902 Trmq3 MGI:MGI:3040094 +100034903 Cocia12 MGI:MGI:3040203 +100034904 Eae34 MGI:MGI:3040309 +100034905 Spha1 MGI:MGI:3040362 +100034906 Spha3 MGI:MGI:3040364 +100034907 Elsgp3 MGI:MGI:3040463 +100034908 Hdlq23 MGI:MGI:3041285 +100034909 Hdlq27 MGI:MGI:3041289 +100034910 Hdlq28 MGI:MGI:3041290 +100034911 Hdlq29 MGI:MGI:3041291 +100034912 Hdlq32 MGI:MGI:3041294 +100034913 Trmq4 MGI:MGI:3042194 +100034914 Cia30 MGI:MGI:3042197 +100034915 Cia31 MGI:MGI:3042198 +100034916 Orgwq9 MGI:MGI:3042418 +100034917 Lmblgq1 MGI:MGI:3042419 +100034918 Lmblgq4 MGI:MGI:3042422 +100034919 Lmblgq6 MGI:MGI:3042424 +100034920 Kidq1 MGI:MGI:3042881 +100034921 Hrtq3 MGI:MGI:3042911 +100034922 Lvrq4 MGI:MGI:3042913 +100034923 Tesq3 MGI:MGI:3042914 +100034924 Scfq3 MGI:MGI:3042918 +100034925 Lvrq10 MGI:MGI:3042919 +100034926 Scfq2 MGI:MGI:3042922 +100034927 Epfpq4 MGI:MGI:3042924 +100034928 Scfq4 MGI:MGI:3042927 +100034929 Fpdty MGI:MGI:3043726 +100034930 Char7 MGI:MGI:3043796 +100034931 Tesw1 MGI:MGI:3044628 +100034932 Ethm1 MGI:MGI:3044648 +100034933 Ethm4 MGI:MGI:3044651 +100034934 Vtbt9 MGI:MGI:3045051 +100034935 Vtbt11 MGI:MGI:3045053 +100034936 Vtbt15 MGI:MGI:3045057 +100034937 Vtbt16 MGI:MGI:3045058 +100034938 Vtbt19 MGI:MGI:3045061 +100034939 Ncilt MGI:MGI:3045604 +100034940 Pfat4 MGI:MGI:3046216 +100034941 Gluchos3 MGI:MGI:3046235 +100034942 Lppl1 MGI:MGI:3046324 +100034943 Phl2 MGI:MGI:3046340 +100034944 Angfq4 MGI:MGI:3046558 +100034945 Alprf MGI:MGI:3046820 +100034946 Igf1sl2 MGI:MGI:3046874 +100034947 Igf1sl4 MGI:MGI:3046876 +100034948 Si5lq4 MGI:MGI:3047364 +100034949 Si5lq6 MGI:MGI:3047366 +100034950 Arti2 MGI:MGI:3051293 +100034951 Thyct1 MGI:MGI:3051294 +100034952 Heal13 MGI:MGI:3051549 +100034953 Bsbob5 MGI:MGI:3051761 +100034954 Hipp3 MGI:MGI:3052076 +100034955 Plyid MGI:MGI:3052201 +100034956 Bmca MGI:MGI:3052784 +100034957 Apsic4 MGI:MGI:3053412 +100034958 Alcrsp3 MGI:MGI:3053620 +100034959 Alcrsp6 MGI:MGI:3053625 +100034960 Brmth2 MGI:MGI:3053758 +100034961 Brmth5 MGI:MGI:3053761 +100034962 Brmth8 MGI:MGI:3053764 +100034963 Brmth11 MGI:MGI:3053872 +100034964 Mdmsc4 MGI:MGI:3054068 +100034965 Bmd21 MGI:MGI:3054100 +100034966 Mp53d1 MGI:MGI:3054216 +100034967 Mp53d3 MGI:MGI:3054218 +100034968 Tgct3 MGI:MGI:3054747 +100034969 Tilss1 MGI:MGI:3055198 +100034970 Hyplip2 MGI:MGI:3056081 +100034971 Bpq10 MGI:MGI:3057293 +100034972 Bpq11 MGI:MGI:3057294 +100034973 Lskcn2 MGI:MGI:3487137 +100034974 Mastr MGI:MGI:3497710 +100034975 Bwnd2wk2 MGI:MGI:3497850 +100034977 Depmq1 MGI:MGI:3510107 +100034979 Bwnd2wk5 MGI:MGI:3510139 +100034983 Bwnd2wk7 MGI:MGI:3510180 +100034984 Vgot2 MGI:MGI:3510185 +100034985 Skmw6 MGI:MGI:3510239 +100034986 Skmw8 MGI:MGI:3510241 +100034987 Skmw10 MGI:MGI:3510244 +100034988 Ssta5 MGI:MGI:3510707 +100034989 Grwtj2 MGI:MGI:3510720 +100034990 Grwtj3 MGI:MGI:3510721 +100034991 Lprq1 MGI:MGI:3511265 +100034992 Lprq2 MGI:MGI:3511270 +100034993 Bmch4 MGI:MGI:3511309 +100034994 Bmch5 MGI:MGI:3511310 +100034995 Bmch7 MGI:MGI:3511312 +100034996 Bdmsq MGI:MGI:3511596 +100034997 Lprq4 MGI:MGI:3511879 +100034998 Pltct1 MGI:MGI:3512144 +100034999 Pltct2 MGI:MGI:3512145 +100035000 Espq2 MGI:MGI:3512158 +100035001 Estoq2 MGI:MGI:3512163 +100035002 Dfq1 MGI:MGI:3512166 +100035003 Lfq1 MGI:MGI:3512167 +100035004 Lfq2 MGI:MGI:3512168 +100035005 Orq2 MGI:MGI:3512171 +100035006 Orq3 MGI:MGI:3512172 +100035007 Bywq MGI:MGI:3512248 +100035008 Fmgty1 MGI:MGI:3512789 +100035009 Fmgty3 MGI:MGI:3512801 +100035010 Fmgty5 MGI:MGI:3512918 +100035011 Fmgty7 MGI:MGI:3512922 +100035012 Fmgty10 MGI:MGI:3512930 +100035013 Fmgty12 MGI:MGI:3512951 +100035014 Fmgty14 MGI:MGI:3512953 +100035015 Noan1 MGI:MGI:3513462 +100035016 Ahl6 MGI:MGI:3514195 +100035017 Hdl34 MGI:MGI:3514357 +100035018 Hdl35 MGI:MGI:3514358 +100035019 Hdl36 MGI:MGI:3514359 +100035020 Hdl37 MGI:MGI:3514360 +100035021 C7mlq MGI:MGI:3514364 +100035022 Ecla MGI:MGI:3521796 +100035023 Eclc MGI:MGI:3521797 +100035024 Mgdr2 MGI:MGI:3521867 +100035025 Lgdr1 MGI:MGI:3521870 +100035026 Ablp MGI:MGI:3521872 +100035027 Axtq1 MGI:MGI:3521952 +100035028 Axtq2 MGI:MGI:3521953 +100035029 Axtq3 MGI:MGI:3521954 +100035030 Etan1 MGI:MGI:3522104 +100035031 Arigm1 MGI:MGI:3524749 +100035032 Arigm2 MGI:MGI:3524750 +100035033 Arigm4 MGI:MGI:3524752 +100035034 Arigm7 MGI:MGI:3524755 +100035035 Arigg2 MGI:MGI:3524757 +100035036 Arigg4 MGI:MGI:3524759 +100035037 Arigg6 MGI:MGI:3524761 +100035038 Arigg10 MGI:MGI:3524765 +100035039 Nstr1 MGI:MGI:3524871 +100035040 Rthyd1 MGI:MGI:3525119 +100035041 Rthyd4 MGI:MGI:3525122 +100035042 Pnhdlc3 MGI:MGI:3525297 +100035043 Pnhdlc5 MGI:MGI:3525299 +100035044 Phdlc1 MGI:MGI:3525300 +100035045 Kdnw1 MGI:MGI:3525628 +100035046 Dbts1 MGI:MGI:3525629 +100035047 Obsty2 MGI:MGI:3525631 +100035048 Obsty3 MGI:MGI:3525632 +100035049 Bwtn1 MGI:MGI:3525636 +100035050 Kdnw3 MGI:MGI:3525637 +100035051 Dbts2 MGI:MGI:3525639 +100035052 W3q12 MGI:MGI:3526902 +100035053 Lgq5 MGI:MGI:3526903 +100035054 W10q7 MGI:MGI:3526906 +100035055 Lgaq3 MGI:MGI:3526908 +100035056 Egq1 MGI:MGI:3526909 +100035057 W3q1 MGI:MGI:3526912 +100035058 W3q2 MGI:MGI:3526913 +100035059 Lgq2 MGI:MGI:3526917 +100035060 Lgaq2 MGI:MGI:3526918 +100035061 Lgq3 MGI:MGI:3526921 +100035062 Lgaq4 MGI:MGI:3526922 +100035063 Egq3 MGI:MGI:3526924 +100035064 W6q7 MGI:MGI:3526926 +100035065 W6q15 MGI:MGI:3526929 +100035066 W10q10 MGI:MGI:3526931 +100035067 Lgq6 MGI:MGI:3526933 +100035068 W10q16 MGI:MGI:3526934 +100035069 W10q11 MGI:MGI:3526938 +100035070 Tailq5 MGI:MGI:3526941 +100035071 W6q17 MGI:MGI:3526942 +100035072 W3q10 MGI:MGI:3526944 +100035073 W10q13 MGI:MGI:3526956 +100035074 Egq12 MGI:MGI:3527050 +100035075 W10q14 MGI:MGI:3527051 +100035076 W6q6 MGI:MGI:3527498 +100035077 W10q5 MGI:MGI:3527499 +100035078 W6q8 MGI:MGI:3527502 +100035079 Egq9 MGI:MGI:3527503 +100035080 W10q2 MGI:MGI:3527564 +100035081 W6q3 MGI:MGI:3527566 +100035082 Tailaq1 MGI:MGI:3527595 +100035083 Egq10 MGI:MGI:3527597 +100035084 Egaq4 MGI:MGI:3527611 +100035085 W10q17 MGI:MGI:3527619 +100035086 Tailaq4 MGI:MGI:3527645 +100035087 W3q7 MGI:MGI:3527648 +100035088 W6q11 MGI:MGI:3527650 +100035089 W10q15 MGI:MGI:3527654 +100035090 W6q12 MGI:MGI:3527656 +100035091 W3q14 MGI:MGI:3527659 +100035092 W3q15 MGI:MGI:3527660 +100035093 Hdlcl1 MGI:MGI:3528033 +100035094 Bdywt MGI:MGI:3528034 +100035095 Hypism MGI:MGI:3528036 +100035096 Manln1 MGI:MGI:3528306 +100035097 Manln2 MGI:MGI:3528307 +100035098 Manln3 MGI:MGI:3528308 +100035099 Manln5 MGI:MGI:3528310 +100035100 Manln6 MGI:MGI:3528311 +100035101 Manln10 MGI:MGI:3528315 +100035102 Manln12 MGI:MGI:3528317 +100035103 Manln14 MGI:MGI:3528319 +100035104 Manln17 MGI:MGI:3528322 +100035105 Manln19 MGI:MGI:3528324 +100035106 Cinda3 MGI:MGI:3529467 +100035107 Cinda5 MGI:MGI:3529469 +100035108 Eae2b MGI:MGI:3530104 +100035109 Swrl1 MGI:MGI:3530664 +100035110 Swrl2 MGI:MGI:3530758 +100035111 Nba4 MGI:MGI:3530760 +100035112 Eae38 MGI:MGI:3530898 +100035113 Baa1 MGI:MGI:3531133 +100035114 Sle16 MGI:MGI:3531330 +100035115 Sle18 MGI:MGI:3531332 +100035116 Obwq4 MGI:MGI:3531519 +100035117 Bwtq9 MGI:MGI:3531522 +100035118 Bwtq10 MGI:MGI:3531523 +100035119 Obq21 MGI:MGI:3531527 +100035120 Obq22 MGI:MGI:3531528 +100035121 Adip10 MGI:MGI:3531535 +100035122 Adip11 MGI:MGI:3531536 +100035123 Adip14 MGI:MGI:3531539 +100035124 Adip16 MGI:MGI:3531541 +100035125 Adip18 MGI:MGI:3531543 +100035126 Gpdc2 MGI:MGI:3573761 +100035127 Aaj1 MGI:MGI:3573901 +100035128 Aaj3 MGI:MGI:3573903 +100035129 Wbcq1 MGI:MGI:3574405 +100035130 Wbcq3 MGI:MGI:3574407 +100035131 Wbcq6 MGI:MGI:3574410 +100035132 Mpvq1 MGI:MGI:3574411 +100035133 Arfix MGI:MGI:3574483 +100035134 Gct7 MGI:MGI:3574497 +100035135 Eamcd2 MGI:MGI:3574853 +100035136 Gstml MGI:MGI:3574911 +100035137 Tcdel1 MGI:MGI:3575696 +100035138 Cspt MGI:MGI:3575698 +100035139 mdlk1 MGI:MGI:3576647 +100035140 Erars1 MGI:MGI:3577035 +100035141 Lith19 MGI:MGI:3577213 +100035142 Lith20 MGI:MGI:3577214 +100035143 Ossc1 MGI:MGI:3577289 +100035144 Scpro4 MGI:MGI:3578824 +100035145 Scpro5 MGI:MGI:3578825 +100035146 Scpro8 MGI:MGI:3578828 +100035147 Scpro10 MGI:MGI:3578830 +100035148 Bntq2 MGI:MGI:3578873 +100035149 Bntq3 MGI:MGI:3578875 +100035150 Bntq6 MGI:MGI:3578879 +100035151 Bntq8 MGI:MGI:3578884 +100035152 Bntq9 MGI:MGI:3578886 +100035153 Bntq12 MGI:MGI:3578890 +100035154 Bntq13 MGI:MGI:3578893 +100035155 Bntq17 MGI:MGI:3578899 +100035156 Sphsr2 MGI:MGI:3579343 +100035157 Idd16.2 MGI:MGI:3579886 +100035159 Nsila2 MGI:MGI:3580542 +100035160 Nsila5 MGI:MGI:3580545 +100035161 Nsila7 MGI:MGI:3580547 +100035162 Crhtaq1 MGI:MGI:3580591 +100035163 Crhtaq2 MGI:MGI:3580592 +100035164 Avptaq2 MGI:MGI:3580595 +100035165 Crhr1taq2 MGI:MGI:3580598 +100035166 Pbmd1 MGI:MGI:3581229 +100035167 Pbmd3 MGI:MGI:3581231 +100035168 Igan3 MGI:MGI:3581247 +100035169 Igan4 MGI:MGI:3581248 +100035170 Agnm1 MGI:MGI:3582415 +100035171 Agnm3 MGI:MGI:3582417 +100035172 Gnf1 MGI:MGI:3582466 +100035173 Emo4 MGI:MGI:3582653 +100035174 Reb1 MGI:MGI:3582654 +100035175 Mord2 MGI:MGI:3583100 +100035176 Cia40 MGI:MGI:3583353 +100035177 Bomd7 MGI:MGI:3583579 +100035178 Ptnu2 MGI:MGI:3583625 +100035179 Ptnu4 MGI:MGI:3583627 +100035180 Ptnu5 MGI:MGI:3583628 +100035181 Salpa4 MGI:MGI:3583889 +100035182 Ath25 MGI:MGI:3586308 +100035183 Ath26 MGI:MGI:3586309 +100035184 Ath28 MGI:MGI:3586311 +100035185 Bw21 MGI:MGI:3586314 +100035186 Bw22 MGI:MGI:3586315 +100035187 Htas5 MGI:MGI:3587072 +100035188 Htas9 MGI:MGI:3587076 +100035189 Cplaq11 MGI:MGI:3588346 +100035190 Artmd1 MGI:MGI:3588383 +100035191 Ses8 MGI:MGI:3588676 +100035192 Ses10 MGI:MGI:3588678 +100035193 Zit1 MGI:MGI:3588721 +100035194 Pbwg15 MGI:MGI:3589175 +100035195 Pbwg18 MGI:MGI:3589178 +100035196 Pbwg20 MGI:MGI:3589180 +100035197 Gsi1 MGI:MGI:3589615 +100035198 Gsi2 MGI:MGI:3589616 +100035199 Vacq1 MGI:MGI:3590246 +100035200 Vacq3 MGI:MGI:3590248 +100035201 Vacq6 MGI:MGI:3590251 +100035202 Exq4 MGI:MGI:3590279 +100035203 Marq1 MGI:MGI:3590510 +100035204 Marq2 MGI:MGI:3590511 +100035205 Marq5 MGI:MGI:3590514 +100035206 Mpdk2 MGI:MGI:3603221 +100035207 Mpdk6 MGI:MGI:3603225 +100035208 Lmrq1 MGI:MGI:3603266 +100035209 Lmrq3 MGI:MGI:3603268 +100035210 Lmrq4 MGI:MGI:3603269 +100035211 Imraq1 MGI:MGI:3603757 +100035212 Imraq2 MGI:MGI:3603758 +100035213 Imrfq2 MGI:MGI:3603761 +100035214 Tmc1m1 MGI:MGI:3604734 +100035215 Tmc1m3 MGI:MGI:3604736 +100035216 Mfiq5 MGI:MGI:3604738 +100035217 Mfiq3 MGI:MGI:3604741 +100035218 Mfiq1 MGI:MGI:3604744 +100035219 Mfeq1 MGI:MGI:3604745 +100035220 Mglcq1 MGI:MGI:3604746 +100035221 Mlepq2 MGI:MGI:3604749 +100035222 Abfp2 MGI:MGI:3604963 +100035223 Abfp5 MGI:MGI:3604966 +100035224 Abfw2 MGI:MGI:3604968 +100035225 Abfw4 MGI:MGI:3604970 +100035226 Bodw1 MGI:MGI:3604973 +100035227 Bodw3 MGI:MGI:3604975 +100035228 Bodw4 MGI:MGI:3604976 +100035229 Knyw1 MGI:MGI:3604977 +100035230 Knyw4 MGI:MGI:3604980 +100035231 Knyw5 MGI:MGI:3604981 +100035232 Spnw3 MGI:MGI:3604985 +100035233 Spnw4 MGI:MGI:3604986 +100035234 Spnw5 MGI:MGI:3604987 +100035235 Bwq7 MGI:MGI:3605813 +100035236 Bmgr2 MGI:MGI:3606052 +100035237 Blmpf4 MGI:MGI:3606259 +100035238 Cfmq1 MGI:MGI:3606273 +100035239 Mtxe1 MGI:MGI:3606288 +100035240 Mtxe3 MGI:MGI:3606290 +100035241 Mtxe5 MGI:MGI:3606292 +100035242 Mtxe8 MGI:MGI:3606295 +100035243 Mtxe9 MGI:MGI:3606296 +100035244 Iba7 MGI:MGI:3606304 +100035245 Rafaril MGI:MGI:3606900 +100035246 Idd21.3 MGI:MGI:3606917 +100035247 Nhdlq8 MGI:MGI:3606930 +100035248 Nhdlq9 MGI:MGI:3606931 +100035249 Hdlq36 MGI:MGI:3607076 +100035250 Hdlq37 MGI:MGI:3607077 +100035251 Hdlq39 MGI:MGI:3607079 +100035252 Sdtq3 MGI:MGI:3607513 +100035253 Sdtq5 MGI:MGI:3607515 +100035254 Sdtq7 MGI:MGI:3607517 +100035255 Sdtq10 MGI:MGI:3607520 +100035256 Mohg1 MGI:MGI:3607561 +100035257 Mohg3 MGI:MGI:3607563 +100035258 Wght1 MGI:MGI:3608826 +100035259 Wght3 MGI:MGI:3608828 +100035260 Wght4 MGI:MGI:3608829 +100035261 Ltxs2 MGI:MGI:3609213 +100035262 Mpvq2 MGI:MGI:3609316 +100035263 Pltq3 MGI:MGI:3609321 +100035264 Dvs1 MGI:MGI:3609561 +100035265 Earheal3 MGI:MGI:3609598 +100035266 Earheal4 MGI:MGI:3609599 +100035267 Bw24 MGI:MGI:3610974 +100035268 Qbis2 MGI:MGI:3612488 +100035269 Eppiq2 MGI:MGI:3612492 +100035270 Cmn3 MGI:MGI:3612502 +100035271 Stheal11 MGI:MGI:3612593 +100035272 Ascla1 MGI:MGI:3613540 +100035273 Ascla5 MGI:MGI:3613544 +100035274 Ath29 MGI:MGI:3613552 +100035275 Chlq1 MGI:MGI:3613641 +100035276 Chlq3 MGI:MGI:3613643 +100035277 Chlq7 MGI:MGI:3613649 +100035278 Chlq8 MGI:MGI:3613650 +100035279 Pmncq1 MGI:MGI:3616890 +100035280 Cafcnq1 MGI:MGI:3616891 +100035281 Hdlq42 MGI:MGI:3618613 +100035282 Hdlq43 MGI:MGI:3618614 +100035283 Hdlq45 MGI:MGI:3618616 +100035284 Hdlq46 MGI:MGI:3618617 +100035285 Hdlq50 MGI:MGI:3618621 +100035286 Hdlq51 MGI:MGI:3618622 +100035287 Ath37 MGI:MGI:3618817 +100035288 Bnszq2 MGI:MGI:3618842 +100035289 Catys1 MGI:MGI:3618862 +100035290 Bmd1c MGI:MGI:3619535 +100035291 Asdq1 MGI:MGI:3619558 +100035292 Asdq2 MGI:MGI:3619559 +100035293 Asdq5 MGI:MGI:3619562 +100035294 Pgis1 MGI:MGI:3622194 +100035295 Rbcq1 MGI:MGI:3622207 +100035296 Rbcq3 MGI:MGI:3622209 +100035297 Rbcq4 MGI:MGI:3622210 +100035298 Mcvq1 MGI:MGI:3622214 +100035299 Chcmq1 MGI:MGI:3622217 +100035300 Srilp MGI:MGI:3622817 +100035301 Cmv4 MGI:MGI:3623882 +100035302 Cq4 MGI:MGI:3624134 +100035303 Bodwt2 MGI:MGI:3624641 +100035304 Scgq2 MGI:MGI:3624656 +100035305 Sxbq1 MGI:MGI:3624658 +100035306 Scgq4 MGI:MGI:3624668 +100035307 Sxbq4 MGI:MGI:3624754 +100035308 Sxbq3 MGI:MGI:3624757 +100035309 Acla2 MGI:MGI:3625040 +100035310 Myci1 MGI:MGI:3625041 +100035311 Myci2 MGI:MGI:3625042 +100035312 Lmr18 MGI:MGI:3625868 +100035313 Prtia1 MGI:MGI:3626077 +100035314 Gwth1 MGI:MGI:3629098 +100035315 Gwth2 MGI:MGI:3629099 +100035316 Orgwt2 MGI:MGI:3629102 +100035317 Orgwt3 MGI:MGI:3629103 +100035318 Orgwt4 MGI:MGI:3629104 +100035319 Orgwt6 MGI:MGI:3629108 +100035320 Orgwt7 MGI:MGI:3629109 +100035321 Gwth4 MGI:MGI:3629110 +100035322 Gwth5 MGI:MGI:3629113 +100035323 Fatpad6 MGI:MGI:3629115 +100035324 Gwth6 MGI:MGI:3629117 +100035325 Brnvl1 MGI:MGI:3629178 +100035326 Brnvl2 MGI:MGI:3629179 +100035327 Bpq13 MGI:MGI:3629725 +100035328 Ntta2 MGI:MGI:3629793 +100035329 Nilac2 MGI:MGI:3629966 +100035330 Nilac4 MGI:MGI:3629971 +100035331 Nilac8 MGI:MGI:3629978 +100035332 Nilac10 MGI:MGI:3629981 +100035333 Ctex MGI:MGI:3639484 +100035334 Elads4 MGI:MGI:3639709 +100035335 Elcs2 MGI:MGI:3639715 +100035336 Elyms1 MGI:MGI:3639716 +100035337 Lbn1 MGI:MGI:3639902 +100035339 Org2 MGI:MGI:3639908 +100035340 Org3 MGI:MGI:3639909 +100035341 Org4 MGI:MGI:3639951 +100035342 Lbn5 MGI:MGI:3639952 +100035343 Bod3 MGI:MGI:3639953 +100035344 Lbn7 MGI:MGI:3639957 +100035345 Bod5 MGI:MGI:3639958 +100035346 Org6 MGI:MGI:3639965 +100035347 Bod6 MGI:MGI:3639966 +100035348 Bwtn3 MGI:MGI:3639968 +100035349 Org8 MGI:MGI:3639970 +100035350 Bod9 MGI:MGI:3639973 +100035351 Org9 MGI:MGI:3639982 +100035352 Org10 MGI:MGI:3639984 +100035353 Bwtn5 MGI:MGI:3639985 +100035354 Neogq1 MGI:MGI:3640530 +100035355 Fecq4 MGI:MGI:3640532 +100035356 Pregq1 MGI:MGI:3640533 +100035357 Pregq4 MGI:MGI:3640536 +100035358 Skmw13 MGI:MGI:3640571 +100035359 Skmw16 MGI:MGI:3640574 +100035360 Skmw17 MGI:MGI:3640575 +100035361 Etax2 MGI:MGI:3641457 +100035362 Ccmp1 MGI:MGI:3641458 +100035363 Ccmp2 MGI:MGI:3641461 +100035364 Ccmp3 MGI:MGI:3641462 +100035365 Ccmp4 MGI:MGI:3641463 +100035366 Ccmp6 MGI:MGI:3641467 +100035367 Etax7 MGI:MGI:3641468 +100035368 Etax8 MGI:MGI:3652359 +100035369 Etax11 MGI:MGI:3652361 +100035370 Alpq1 MGI:MGI:3652893 +100035371 Alpq3 MGI:MGI:3652895 +100035372 Hemq1 MGI:MGI:3652905 +100035373 Hemq4 MGI:MGI:3652908 +100035374 Hemq5 MGI:MGI:3652909 +100035375 Advh3 MGI:MGI:3653386 +100035376 Bfsz1 MGI:MGI:3654069 +100035377 Smtw1 MGI:MGI:3654113 +100035378 Spmd1 MGI:MGI:3654115 +100035379 Spmd4 MGI:MGI:3654118 +100035380 Raml2 MGI:MGI:3655631 +100035381 Raml5 MGI:MGI:3655634 +100035382 Mohg4 MGI:MGI:3656277 +100035383 Mohg7 MGI:MGI:3656280 +100035384 Mohg9 MGI:MGI:3656282 +100035385 Modor2 MGI:MGI:3656498 +100035386 Clas3 MGI:MGI:3662679 +100035387 Azdm1 MGI:MGI:3663046 +100035388 Azdm2 MGI:MGI:3663047 +100035389 Azdm5 MGI:MGI:3663050 +100035390 Mskt2 MGI:MGI:3663603 +100035391 Mskt3 MGI:MGI:3663604 +100035392 Mskt5 MGI:MGI:3663606 +100035393 Mskt8 MGI:MGI:3663609 +100035394 Mskt9 MGI:MGI:3663610 +100035395 Anyt1 MGI:MGI:3663642 +100035396 Imct1 MGI:MGI:3663643 +100035397 Blct3 MGI:MGI:3663646 +100035398 Blct4 MGI:MGI:3663647 +100035399 Byln1 MGI:MGI:3663653 +100035400 Blct6 MGI:MGI:3663654 +100035401 Sttr2 MGI:MGI:3663655 +100035402 Mpcp2 MGI:MGI:3664222 +100035403 Mpcp4 MGI:MGI:3664224 +100035404 Mpcp8 MGI:MGI:3664228 +100035405 Mpcp10 MGI:MGI:3664230 +100035406 Dbm1 MGI:MGI:3664266 +100035407 Dbm2 MGI:MGI:3664267 +100035408 Chlq10 MGI:MGI:3665176 +100035409 Chlq13 MGI:MGI:3665180 +100035410 Chlq15 MGI:MGI:3665183 +100035411 Chlq18 MGI:MGI:3665195 +100035412 Hmtb3 MGI:MGI:3688275 +100035413 Bczr2 MGI:MGI:3688575 +100035414 Elorr1 MGI:MGI:3688590 +100035415 Slms2 MGI:MGI:3688605 +100035416 Elnv MGI:MGI:3688629 +100035417 Elda4 MGI:MGI:3689516 +100035418 Wtlr1 MGI:MGI:3689539 +100035419 Wtlr2 MGI:MGI:3689540 +100035420 Nashs1 MGI:MGI:3690342 +100035421 Msts1 MGI:MGI:3690346 +100035422 Slcs1 MGI:MGI:3690354 +100035423 Nhil3 MGI:MGI:3691599 +100035424 Nhil4 MGI:MGI:3691600 +100035425 Tbt1 MGI:MGI:3691642 +100035426 Tbt3 MGI:MGI:3691644 +100035427 Fcs2 MGI:MGI:3691666 +100035428 Brwt1 MGI:MGI:3691686 +100035429 Brwt2 MGI:MGI:3691687 +100035430 Brwt3 MGI:MGI:3691688 +100035431 Hfem3 MGI:MGI:3692627 +100035432 Hfem4 MGI:MGI:3692628 +100035433 Ctrq3 MGI:MGI:3692643 +100035434 Dbsq1 MGI:MGI:3693573 +100035435 Dbsq4 MGI:MGI:3693576 +100035436 Dbsq7 MGI:MGI:3693579 +100035437 Eac2 MGI:MGI:3693654 +100035438 Eac3 MGI:MGI:3693655 +100035439 Eac6 MGI:MGI:3693658 +100035440 Ity6 MGI:MGI:3694092 +100035441 Ity8 MGI:MGI:3694094 +100035442 Brml1 MGI:MGI:3694904 +100035443 Brml5 MGI:MGI:3694908 +100035444 Brml7 MGI:MGI:3694910 +100035445 Bmd24 MGI:MGI:3694911 +100035446 Pstc1 MGI:MGI:3694914 +100035447 Pstc5 MGI:MGI:3694918 +100035448 Amdt1 MGI:MGI:3695445 +100035449 Ctpr1 MGI:MGI:3695470 +100035450 Imab MGI:MGI:3696448 +100035451 Psrs1 MGI:MGI:3697132 +100035452 Psrs2 MGI:MGI:3697134 +100035453 Psrs4 MGI:MGI:3697136 +100035454 Psrs6 MGI:MGI:3697138 +100035455 Vmmt2 MGI:MGI:3697190 +100035456 Vmmt6 MGI:MGI:3697194 +100035457 Vmmt9 MGI:MGI:3697197 +100035458 Vmmt12 MGI:MGI:3697200 +100035459 Vmmt15 MGI:MGI:3697203 +100035460 Vmmt17 MGI:MGI:3697205 +100035461 Imab2 MGI:MGI:3697626 +100035462 Imab3 MGI:MGI:3697627 +100035463 Imab5 MGI:MGI:3697630 +100035464 Bw26 MGI:MGI:3697822 +100035465 Bw28 MGI:MGI:3697824 +100035466 Bw30 MGI:MGI:3697826 +100035467 Bw31 MGI:MGI:3697827 +100035468 Bdln7 MGI:MGI:3697829 +100035469 Lbm14 MGI:MGI:3697831 +100035470 Abfm1 MGI:MGI:3697834 +100035471 Rfpw1 MGI:MGI:3697837 +100035472 Bmc1 MGI:MGI:3697838 +100035473 Bmnx MGI:MGI:3697842 +100035474 Ftm2 MGI:MGI:3697844 +100035475 Mofp2 MGI:MGI:3697848 +100035476 Gf6 MGI:MGI:3697850 +100035477 Bmc2 MGI:MGI:3697853 +100035478 Bmd27 MGI:MGI:3697855 +100035479 Bmd32 MGI:MGI:3697857 +100035480 Bmd29 MGI:MGI:3697860 +100035481 Mofp3 MGI:MGI:3697863 +100035482 Gf4 MGI:MGI:3697866 +100035483 Rfpw4 MGI:MGI:3697868 +100035484 Ba1 MGI:MGI:3698436 +100035485 Bmc3 MGI:MGI:3698438 +100035486 Bdln9 MGI:MGI:3698442 +100035487 Lbm12 MGI:MGI:3698443 +100035488 Ba2 MGI:MGI:3698445 +100035489 Bmc4 MGI:MGI:3698447 +100035490 Ba3 MGI:MGI:3698451 +100035491 Bmc5 MGI:MGI:3698453 +100035492 Bmc10 MGI:MGI:3698454 +100035493 Gf5 MGI:MGI:3698457 +100035494 Bmd30 MGI:MGI:3698461 +100035495 Bmd31 MGI:MGI:3698462 +100035496 Mofp4 MGI:MGI:3698468 +100035497 Wg5 MGI:MGI:3698533 +100035498 Swq6 MGI:MGI:3698536 +100035499 Kwq13 MGI:MGI:3698537 +100035500 Kwq14 MGI:MGI:3698538 +100035501 Tailq7 MGI:MGI:3698540 +100035502 Tailq8 MGI:MGI:3698541 +100035503 Fatmq2 MGI:MGI:3698544 +100035504 Tcq1 MGI:MGI:3698545 +100035505 Brwq1 MGI:MGI:3698547 +100035506 Lwq9 MGI:MGI:3698548 +100035507 Mfat1 MGI:MGI:3699284 +100035508 Mfat4 MGI:MGI:3699288 +100035509 Mfat6 MGI:MGI:3699295 +100035510 Chldq1 MGI:MGI:3699365 +100035511 Chldq2 MGI:MGI:3699366 +100035512 Tglq1 MGI:MGI:3699367 +100035513 Chldq3 MGI:MGI:3699371 +100035514 Ftms1 MGI:MGI:3699378 +100035515 Chldq5 MGI:MGI:3699379 +100035516 Sox10m2 MGI:MGI:3511472 +100035517 Sox10m4 MGI:MGI:3511474 +100035518 Gutl1 MGI:MGI:3699609 +100035519 Pstc6 MGI:MGI:3699721 +100035520 Pbrbc1 MGI:MGI:3699852 +100035521 Pbrbc3 MGI:MGI:3699854 +100035522 Bmrbc1 MGI:MGI:3699855 +100035523 Bmrbc4 MGI:MGI:3699858 +100035524 Ath9 MGI:MGI:1890350 +100035525 Ses5 MGI:MGI:2137369 +100035526 Kcal2 MGI:MGI:2151837 +100035527 Tshp1 MGI:MGI:2386691 +100035528 Tshp11 MGI:MGI:2386701 +100035529 Tshp16 MGI:MGI:2386708 +100035530 Hdlq2 MGI:MGI:2387135 +100035531 Mnic3 MGI:MGI:2387558 +100035532 Bdln5 MGI:MGI:2446732 +100035533 Hdlq5 MGI:MGI:2448338 +100035534 Tnbs1 MGI:MGI:2451075 +100035535 Lith9 MGI:MGI:2653454 +100035536 Lmr4 MGI:MGI:2656510 +100035537 Pgia25 MGI:MGI:2656527 +100035538 Cia17 MGI:MGI:2656534 +100035539 Lbm10 MGI:MGI:2656811 +100035540 Ssta4 MGI:MGI:2661147 +100035541 Cfld4 MGI:MGI:2661735 +100035542 Sbmd2 MGI:MGI:2662976 +100035543 Hypn MGI:MGI:2663450 +100035544 Ltsd5 MGI:MGI:2664842 +100035545 Hscfr MGI:MGI:2665081 +100035546 Fcsa3 MGI:MGI:2668937 +100035547 Loco1 MGI:MGI:2669258 +100035548 Aod3 MGI:MGI:2670442 +100035549 Ofca2 MGI:MGI:2670606 +100035550 Alaa4 MGI:MGI:2677753 +100035551 Loca2 MGI:MGI:2680103 +100035552 Angvq2 MGI:MGI:2683514 +100035553 Tgq3 MGI:MGI:2686911 +100035554 Im6 MGI:MGI:3032860 +100035555 Skmw4 MGI:MGI:3036185 +100035556 Fibrs3 MGI:MGI:3036579 +100035557 Moo2 MGI:MGI:3037101 +100035558 Fbgl2 MGI:MGI:3038477 +100035559 Cia28 MGI:MGI:3039460 +100035560 Eae33 MGI:MGI:3040308 +100035561 Hdlq31 MGI:MGI:3041293 +100035562 Trmq6 MGI:MGI:3042196 +100035563 Lmblgq5 MGI:MGI:3042423 +100035564 Kidpq2 MGI:MGI:3042910 +100035565 Splq8 MGI:MGI:3042925 +100035566 T1pdty MGI:MGI:3043727 +100035567 Ofact MGI:MGI:3044643 +100035568 Vtbt12 MGI:MGI:3045054 +100035569 Rplag MGI:MGI:3045765 +100035570 Phl1 MGI:MGI:3046339 +100035571 Lpolv MGI:MGI:3046899 +100035572 Alcdp2 MGI:MGI:3050454 +100035573 Hdlq33 MGI:MGI:3052868 +100035574 Apsic2 MGI:MGI:3053410 +100035575 Brmth4 MGI:MGI:3053760 +100035576 Mdmsc6 MGI:MGI:3054070 +100035577 Ducm1 MGI:MGI:3055206 +100035578 Hrq4 MGI:MGI:3057295 +100035580 Bwnd4wk4 MGI:MGI:3510141 +100035582 Vgot1 MGI:MGI:3510184 +100035583 Bmch3 MGI:MGI:3511308 +100035584 Lprq5 MGI:MGI:3511880 +100035585 Espq3 MGI:MGI:3512159 +100035586 Orq1 MGI:MGI:3512170 +100035587 Xydsq MGI:MGI:3512247 +100035588 Fmgty11 MGI:MGI:3512950 +100035589 Salpa2 MGI:MGI:3514274 +100035590 Hdl38 MGI:MGI:3514361 +100035591 Hmdc MGI:MGI:3521868 +100035592 Parms1 MGI:MGI:3522455 +100035593 Arigm5 MGI:MGI:3524753 +100035594 Arigg8 MGI:MGI:3524763 +100035595 Rthyd5 MGI:MGI:3525123 +100035596 Phdlc2 MGI:MGI:3525301 +100035597 Kdnw2 MGI:MGI:3525635 +100035598 Obsty5 MGI:MGI:3525640 +100035599 W6q14 MGI:MGI:3526905 +100035600 Egq2 MGI:MGI:3526915 +100035601 W6q13 MGI:MGI:3526930 +100035602 Egq8 MGI:MGI:3526935 +100035603 Egq11 MGI:MGI:3526940 +100035604 W3q5 MGI:MGI:3526954 +100035605 W6q9 MGI:MGI:3527052 +100035606 Egq4 MGI:MGI:3527570 +100035607 W6q16 MGI:MGI:3527612 +100035608 Egq5 MGI:MGI:3527652 +100035609 Egq6 MGI:MGI:3527657 +100035610 Manln4 MGI:MGI:3528309 +100035611 Manln11 MGI:MGI:3528316 +100035612 Manln16 MGI:MGI:3528321 +100035613 Nba3 MGI:MGI:3530666 +100035614 Baa2 MGI:MGI:3531134 +100035615 Bwtq8 MGI:MGI:3531521 +100035616 Obq20 MGI:MGI:3531526 +100035617 Adip12 MGI:MGI:3531537 +100035618 Aaj2 MGI:MGI:3573902 +100035619 Aaj4 MGI:MGI:3573904 +100035620 Cmv3 MGI:MGI:3574425 +100035621 Motp1 MGI:MGI:3575566 +100035622 Lith15 MGI:MGI:3576865 +100035623 Lith18 MGI:MGI:3577212 +100035624 Scpro6 MGI:MGI:3578826 +100035625 Bntq5 MGI:MGI:3578878 +100035626 Bntq10 MGI:MGI:3578888 +100035627 Bntq15 MGI:MGI:3578896 +100035628 spkw2 MGI:MGI:3580138 +100035629 Nsila9 MGI:MGI:3580549 +100035630 Avptaq1 MGI:MGI:3580594 +100035631 Gnf2 MGI:MGI:3582467 +100035632 Bomd5 MGI:MGI:3583577 +100035633 Ptnu3 MGI:MGI:3583626 +100035634 Ath22 MGI:MGI:3586305 +100035635 Bw20 MGI:MGI:3586312 +100035636 Ses6 MGI:MGI:3588674 +100035637 Msq1 MGI:MGI:3588679 +100035638 Pbwg21 MGI:MGI:3589181 +100035639 Bdw1 MGI:MGI:3589618 +100035640 Tsiq1 MGI:MGI:3590286 +100035641 Mpdk8 MGI:MGI:3603244 +100035642 Idd25 MGI:MGI:3603297 +100035643 Tmc1m4 MGI:MGI:3604737 +100035644 Mfiq4 MGI:MGI:3604747 +100035645 Abfw3 MGI:MGI:3604969 +100035646 Bodw2 MGI:MGI:3604974 +100035647 Knyw3 MGI:MGI:3604979 +100035648 Spnw7 MGI:MGI:3604989 +100035649 Blmpf3 MGI:MGI:3606258 +100035650 Mtxe2 MGI:MGI:3606289 +100035651 Iba8 MGI:MGI:3606305 +100035652 Hdlq35 MGI:MGI:3607075 +100035653 Sdtq6 MGI:MGI:3607516 +100035654 Wght2 MGI:MGI:3608827 +100035655 Idd27 MGI:MGI:3608893 +100035656 Earheal1 MGI:MGI:3609596 +100035657 Efw MGI:MGI:3609662 +100035658 Cmn2 MGI:MGI:3612501 +100035659 Ascla2 MGI:MGI:3613541 +100035660 Chlq4 MGI:MGI:3613645 +100035661 Hdlq44 MGI:MGI:3618615 +100035662 Hdlq49 MGI:MGI:3618620 +100035663 917M MGI:MGI:3620954 +100035664 Asdq3 MGI:MGI:3619560 +100035665 Ua1 MGI:MGI:3622170 +100035666 Hgbq1 MGI:MGI:3622211 +100035667 Sxbq2 MGI:MGI:3624752 +100035668 Svtms MGI:MGI:3626352 +100035669 Orgwt1 MGI:MGI:3629101 +100035670 Orgwt5 MGI:MGI:3629106 +100035671 Fatpad3 MGI:MGI:3629111 +100035672 Gwth7 MGI:MGI:3629118 +100035673 Nilac6 MGI:MGI:3629974 +100035674 Nilac11 MGI:MGI:3629982 +100035675 Elyms2 MGI:MGI:3639717 +100035676 Bod4 MGI:MGI:3639955 +100035677 Lbn9 MGI:MGI:3639964 +100035678 Bod10 MGI:MGI:3639981 +100035679 Skts15 MGI:MGI:3640316 +100035680 Pregq2 MGI:MGI:3640534 +100035681 Bw25 MGI:MGI:3641053 +100035682 Etax6 MGI:MGI:3641465 +100035683 Ccmp9 MGI:MGI:3652363 +100035684 Hemq2 MGI:MGI:3652906 +100035685 Spmd3 MGI:MGI:3654117 +100035686 Mohg6 MGI:MGI:3656279 +100035687 Mohg8 MGI:MGI:3656281 +100035688 Clas2 MGI:MGI:3662678 +100035689 Mskt1 MGI:MGI:3663602 +100035690 W6bw1 MGI:MGI:3663645 +100035691 Sttr1 MGI:MGI:3663652 +100035692 Mpcp6 MGI:MGI:3664226 +100035693 Dbm4 MGI:MGI:3664269 +100035694 Chlq17 MGI:MGI:3665185 +100035695 Bczr3 MGI:MGI:3688576 +100035696 Lore9 MGI:MGI:3689525 +100035697 Msts2 MGI:MGI:3690347 +100035698 Tbt2 MGI:MGI:3691643 +100035699 Brwt4 MGI:MGI:3691689 +100035700 Ctrq1 MGI:MGI:3692641 +100035701 Dbsq8 MGI:MGI:3693580 +100035702 Ity4 MGI:MGI:3694090 +100035703 Actre5 MGI:MGI:3694111 +100035704 Pstc4 MGI:MGI:3694917 +100035705 Char2b MGI:MGI:3697101 +100035706 Psrs5 MGI:MGI:3697137 +100035707 Vmmt18 MGI:MGI:3697206 +100035708 Imab4 MGI:MGI:3697628 +100035709 Bw29 MGI:MGI:3697825 +100035710 Lbm11 MGI:MGI:3697830 +100035711 Pbft2 MGI:MGI:3697847 +100035712 Rfpw6 MGI:MGI:3697852 +100035713 Mofp6 MGI:MGI:3697864 +100035714 Bdln8 MGI:MGI:3698441 +100035715 Ba5 MGI:MGI:3698446 +100035716 Ba6 MGI:MGI:3698452 +100035717 Ses1a MGI:MGI:2136999 +100035718 Pbctlp1 MGI:MGI:2135766 +100035719 Mnic1 MGI:MGI:2151779 +100035720 Smdq3 MGI:MGI:2179704 +100035721 Lhyp MGI:MGI:2386617 +100035722 Tcsz1 MGI:MGI:2386688 +100035723 Tshp3 MGI:MGI:2386693 +100035724 Hdlq3 MGI:MGI:2387136 +100035725 Sbnt1 MGI:MGI:2387317 +100035726 Sluc26 MGI:MGI:2387371 +100035727 Nociq1 MGI:MGI:2388669 +100035728 Otx2m1 MGI:MGI:2445326 +100035729 Adip9 MGI:MGI:2446735 +100035730 Bdln6 MGI:MGI:2447999 +100035731 Ath18 MGI:MGI:2451364 +100035732 Nhdlq2 MGI:MGI:2653467 +100035734 Obq18 MGI:MGI:2656144 +100035735 Lmr5 MGI:MGI:2656511 +100035736 Pgia23 MGI:MGI:2656525 +100035737 Pgia24 MGI:MGI:2656526 +100035738 Cia18 MGI:MGI:2656535 +100035739 Lbm5 MGI:MGI:2656806 +100035740 Giq1 MGI:MGI:2660559 +100035741 Musz1 MGI:MGI:2660611 +100035742 Cd8mts2 MGI:MGI:2661243 +100035743 Scon1 MGI:MGI:2661413 +100035744 Cfbw4 MGI:MGI:2661706 +100035745 Hrq2 MGI:MGI:2662842 +100035746 Sbmd4 MGI:MGI:2662978 +100035747 Bel MGI:MGI:2663495 +100035748 Vent3 MGI:MGI:2664092 +100035749 Radpf3 MGI:MGI:2664725 +100035750 Ltsd7 MGI:MGI:2664844 +100035751 Pcyts1 MGI:MGI:2665061 +100035752 Pcyts5 MGI:MGI:2665066 +100035753 Tbbmd6 MGI:MGI:2668919 +100035754 Mbis3 MGI:MGI:2669463 +100035755 Cfcd MGI:MGI:2669473 +100035756 Pcfm1 MGI:MGI:2670129 +100035757 Cfsw1 MGI:MGI:2670599 +100035758 Ofca1 MGI:MGI:2670605 +100035759 Fob3a MGI:MGI:2670912 +100035760 Marif3 MGI:MGI:2677757 +100035761 Loca1 MGI:MGI:2680102 +100035762 Aaom1 MGI:MGI:2680905 +100035763 Scc11 MGI:MGI:2680973 +100035764 Pltpq3 MGI:MGI:2684020 +100035765 Nhdlq7 MGI:MGI:2686906 +100035766 Hbnr7 MGI:MGI:2687241 +100035767 Abbp1 MGI:MGI:3026891 +100035768 Im7 MGI:MGI:3032863 +100035769 Pbwg4 MGI:MGI:3035961 +100035770 Pbwg7 MGI:MGI:3035964 +100035771 Skmw3 MGI:MGI:3036184 +100035772 Vmbic10 MGI:MGI:3036608 +100035773 Lvic4 MGI:MGI:3036612 +100035774 Moo4 MGI:MGI:3037103 +100035775 Tgls1 MGI:MGI:3038480 +100035776 Cia27 MGI:MGI:3039459 +100035777 Lscc3 MGI:MGI:3040191 +100035778 Eae30 MGI:MGI:3040311 +100035779 Elsgp4 MGI:MGI:3040483 +100035780 Hdlq26 MGI:MGI:3041288 +100035781 Hdlq30 MGI:MGI:3041292 +100035782 Cia32 MGI:MGI:3042199 +100035783 Orgwq8 MGI:MGI:3042417 +100035784 Lmblgq2 MGI:MGI:3042420 +100035785 Scfpq1 MGI:MGI:3042912 +100035786 Tesq1 MGI:MGI:3042920 +100035787 Epfpq1 MGI:MGI:3042921 +100035788 Splq9 MGI:MGI:3042926 +100035789 Mmtp2 MGI:MGI:3043751 +100035790 Tesw2 MGI:MGI:3044629 +100035791 Vtbt5 MGI:MGI:3045047 +100035792 Vtbt10 MGI:MGI:3045052 +100035793 Vtbt18 MGI:MGI:3045060 +100035794 Tabw2 MGI:MGI:3045410 +100035795 Gluchos1 MGI:MGI:3046233 +100035796 Lptl1 MGI:MGI:3046325 +100035797 Hpcr2 MGI:MGI:3046737 +100035798 Igf1sl3 MGI:MGI:3046875 +100035799 Arti1 MGI:MGI:3051292 +100035800 Bsbob4 MGI:MGI:3051760 +100035801 Hipp4 MGI:MGI:3052077 +100035802 Apsic3 MGI:MGI:3053411 +100035803 Alcrsp5 MGI:MGI:3053623 +100035804 Brmth3 MGI:MGI:3053759 +100035805 Brmth10 MGI:MGI:3053766 +100035806 Bmd20 MGI:MGI:3054099 +100035807 Tgct2 MGI:MGI:3054746 +100035808 Tgct4 MGI:MGI:3054748 +100035809 Motr1 MGI:MGI:3056341 +100035810 Bpq12 MGI:MGI:3487276 +100035813 Bwnd3wk1 MGI:MGI:3510140 +100035815 Bwnd4wk7 MGI:MGI:3510181 +100035816 Skmw7 MGI:MGI:3510240 +100035817 Ssta7 MGI:MGI:3510709 +100035818 Bmch1 MGI:MGI:3511306 +100035819 Bmch2 MGI:MGI:3511307 +100035820 Char8 MGI:MGI:3511479 +100035821 Espq4 MGI:MGI:3512160 +100035822 Estoq4 MGI:MGI:3512165 +100035823 Lfq3 MGI:MGI:3512169 +100035824 Mhstq2 MGI:MGI:3512246 +100035825 Fmgty8 MGI:MGI:3512925 +100035826 Fmgty13 MGI:MGI:3512952 +100035827 Noan2 MGI:MGI:3513463 +100035828 Hdl39 MGI:MGI:3514362 +100035829 Hdl40 MGI:MGI:3514363 +100035830 Mgdr1 MGI:MGI:3521866 +100035831 Lgdr2 MGI:MGI:3521871 +100035832 Diobq MGI:MGI:3521955 +100035833 Cq6 MGI:MGI:3522038 +100035834 Trglyd MGI:MGI:3522039 +100035835 Arigm6 MGI:MGI:3524754 +100035836 Arigg7 MGI:MGI:3524762 +100035837 Arigg9 MGI:MGI:3524764 +100035838 Nstr2 MGI:MGI:3524872 +100035839 Pnhdlc1 MGI:MGI:3525295 +100035840 Obsty1 MGI:MGI:3525627 +100035841 Adbg1 MGI:MGI:3525630 +100035842 Tgyl1 MGI:MGI:3525633 +100035843 Splwt1 MGI:MGI:3525634 +100035844 W10q6 MGI:MGI:3526904 +100035845 W6q1 MGI:MGI:3526910 +100035846 W10q1 MGI:MGI:3526916 +100035847 Tailq2 MGI:MGI:3526919 +100035848 Egaq1 MGI:MGI:3526925 +100035849 W3q17 MGI:MGI:3526932 +100035850 W3q3 MGI:MGI:3526937 +100035851 W10q18 MGI:MGI:3526943 +100035852 W3q8 MGI:MGI:3526945 +100035853 W3q11 MGI:MGI:3527496 +100035854 W10q8 MGI:MGI:3527500 +100035855 Lgq1 MGI:MGI:3527565 +100035856 W6q10 MGI:MGI:3527596 +100035857 Tailq3 MGI:MGI:3527614 +100035858 W10q12 MGI:MGI:3527651 +100035859 W3q16 MGI:MGI:3527661 +100035860 Athla1 MGI:MGI:3528031 +100035861 Hdlcl2 MGI:MGI:3528035 +100035862 Manln8 MGI:MGI:3528313 +100035863 Manln13 MGI:MGI:3528318 +100035864 Manln18 MGI:MGI:3528323 +100035865 Cxam MGI:MGI:3529496 +100035866 Swrl3 MGI:MGI:3530759 +100035867 Eae36 MGI:MGI:3530896 +100035868 Modc2 MGI:MGI:3530900 +100035869 Sle17 MGI:MGI:3531331 +100035870 Obwq5 MGI:MGI:3531520 +100035871 Bwtq12 MGI:MGI:3531525 +100035872 Adip15 MGI:MGI:3531540 +100035873 Adip17 MGI:MGI:3531542 +100035874 Dice1b MGI:MGI:3573895 +100035875 Wbcq2 MGI:MGI:3574406 +100035877 Gct9 MGI:MGI:3574499 +100035878 Dxmod MGI:MGI:3574879 +100035879 Lith16 MGI:MGI:3576866 +100035880 Lith17 MGI:MGI:3576867 +100035881 Lith23 MGI:MGI:3577226 +100035882 Ossc2 MGI:MGI:3577290 +100035883 Bntq1 MGI:MGI:3578872 +100035884 Bntq7 MGI:MGI:3578882 +100035885 Bntq11 MGI:MGI:3578889 +100035886 Tdmq1 MGI:MGI:3579350 +100035887 Zolw1 MGI:MGI:3580123 +100035888 Nsila1 MGI:MGI:3580541 +100035889 Nsila8 MGI:MGI:3580548 +100035890 Crhtaq3 MGI:MGI:3580593 +100035891 Crhr1taq1 MGI:MGI:3580597 +100035892 Pbmd4 MGI:MGI:3581232 +100035893 Igan2 MGI:MGI:3581246 +100035894 Agnm2 MGI:MGI:3582416 +100035895 Imebt1 MGI:MGI:3583085 +100035896 Bomd6 MGI:MGI:3583578 +100035897 Ath23 MGI:MGI:3586306 +100035898 Ath24 MGI:MGI:3586307 +100035899 Ath27 MGI:MGI:3586310 +100035900 Htas8 MGI:MGI:3587075 +100035901 Cplaq12 MGI:MGI:3588347 +100035902 Ses7 MGI:MGI:3588675 +100035903 Pbwg14 MGI:MGI:3589174 +100035904 Pbwg19 MGI:MGI:3589179 +100035905 Kdw1 MGI:MGI:3589617 +100035906 Hrtfm7 MGI:MGI:3590238 +100035907 Vacq4 MGI:MGI:3590249 +100035908 Tsiq3 MGI:MGI:3590288 +100035909 Mpdk1 MGI:MGI:3603220 +100035910 Mpdk5 MGI:MGI:3603224 +100035911 Lmrq2 MGI:MGI:3603267 +100035912 Lmrq6 MGI:MGI:3603271 +100035913 Imrfq1 MGI:MGI:3603760 +100035914 Mfe5q1 MGI:MGI:3604740 +100035915 Mfi7q1 MGI:MGI:3604743 +100035916 Abfp4 MGI:MGI:3604965 +100035917 Abfw1 MGI:MGI:3604967 +100035918 Knyw2 MGI:MGI:3604978 +100035919 Knyw6 MGI:MGI:3604982 +100035920 Spnw1 MGI:MGI:3604983 +100035921 Bmgr4 MGI:MGI:3606054 +100035922 Blmpf5 MGI:MGI:3606260 +100035923 Cfmq3 MGI:MGI:3606275 +100035924 Mtxe7 MGI:MGI:3606294 +100035925 Rafar2 MGI:MGI:3606899 +100035926 Hdlq34 MGI:MGI:3606929 +100035927 Nhdlq10 MGI:MGI:3606932 +100035928 Sdtq4 MGI:MGI:3607514 +100035929 Sdtq9 MGI:MGI:3607519 +100035930 Sdtq11 MGI:MGI:3607521 +100035931 Wght6 MGI:MGI:3608832 +100035932 Pltq1 MGI:MGI:3609317 +100035933 Earheal2 MGI:MGI:3609597 +100035934 Plep MGI:MGI:3609641 +100035935 Qbis1 MGI:MGI:3612487 +100035936 Eppiq1 MGI:MGI:3612491 +100035937 Ascla6 MGI:MGI:3613545 +100035938 Bglu3 MGI:MGI:3613551 +100035939 Chlq6 MGI:MGI:3613648 +100035940 Hdlq40 MGI:MGI:3618611 +100035941 Hdlq41 MGI:MGI:3618612 +100035942 Ath38 MGI:MGI:3618818 +100035943 Bmd1a MGI:MGI:3619533 +100035944 Asdq4 MGI:MGI:3619561 +100035945 Asdq7 MGI:MGI:3619564 +100035946 Rbcq2 MGI:MGI:3622208 +100035947 Mchq1 MGI:MGI:3622213 +100035948 T2dm2sa MGI:MGI:3622822 +100035949 Cq5 MGI:MGI:3624135 +100035950 Mancq1 MGI:MGI:3624659 +100035951 Acla1 MGI:MGI:3625039 +100035952 Lmr16 MGI:MGI:3625866 +100035953 Lmr17 MGI:MGI:3625867 +100035954 Fatpad1 MGI:MGI:3629100 +100035955 Gwth3 MGI:MGI:3629105 +100035956 Fatpad5 MGI:MGI:3629114 +100035957 Fatpad7 MGI:MGI:3629116 +100035958 Hrq6 MGI:MGI:3629314 +100035959 Ntta3 MGI:MGI:3629794 +100035960 Nilac7 MGI:MGI:3629976 +100035961 Nilac12 MGI:MGI:3629983 +100035962 Elads3 MGI:MGI:3639708 +100035963 Bwtn2 MGI:MGI:3639901 +100035964 Lbn3 MGI:MGI:3639907 +100035965 Lbn4 MGI:MGI:3639950 +100035966 Lbn6 MGI:MGI:3639954 +100035967 Org5 MGI:MGI:3639956 +100035968 Bwtn4 MGI:MGI:3639969 +100035969 Lbn10 MGI:MGI:3639983 +100035970 Skts14 MGI:MGI:3640315 +100035971 Fecq3 MGI:MGI:3640531 +100035972 Skmw12 MGI:MGI:3640570 +100035973 Etax1 MGI:MGI:3641456 +100035974 Etax3 MGI:MGI:3641459 +100035975 Ccmp5 MGI:MGI:3641466 +100035976 Ccmp7 MGI:MGI:3652357 +100035977 Ccmp8 MGI:MGI:3652362 +100035978 Hemq3 MGI:MGI:3652907 +100035979 Hemq6 MGI:MGI:3652910 +100035980 Advh4 MGI:MGI:3653387 +100035981 Smtw2 MGI:MGI:3654114 +100035982 Raml4 MGI:MGI:3655633 +100035983 Modor1 MGI:MGI:3656497 +100035984 Modor3 MGI:MGI:3656499 +100035985 Azdm3 MGI:MGI:3663048 +100035986 Mskt4 MGI:MGI:3663605 +100035987 Mskt6 MGI:MGI:3663607 +100035988 Blct2 MGI:MGI:3663639 +100035989 Bdym1 MGI:MGI:3663640 +100035990 Aspt1 MGI:MGI:3663650 +100035991 Mpcp3 MGI:MGI:3664223 +100035992 Mpcp9 MGI:MGI:3664229 +100035993 Mpcp12 MGI:MGI:3664232 +100035994 Chlq12 MGI:MGI:3665179 +100035995 Chlq16 MGI:MGI:3665184 +100035996 Elda1 MGI:MGI:3688588 +100035997 Elorr2 MGI:MGI:3688591 +100035998 Lore10 MGI:MGI:3689526 +100035999 Wtlr3 MGI:MGI:3689541 +100036000 Msts4 MGI:MGI:3690349 +100036001 Nhil1 MGI:MGI:3691597 +100036002 Tbt4 MGI:MGI:3691645 +100036003 Fcs3 MGI:MGI:3691667 +100036004 Hfem2 MGI:MGI:3692626 +100036005 Dbsq2 MGI:MGI:3693574 +100036006 Dbsq6 MGI:MGI:3693578 +100036007 Eac1 MGI:MGI:3693653 +100036008 Ity5 MGI:MGI:3694091 +100036009 Brml2 MGI:MGI:3694905 +100036010 Brml6 MGI:MGI:3694909 +100036011 Bmd25 MGI:MGI:3694912 +100036012 Pstc3 MGI:MGI:3694916 +100036013 Dshv2 MGI:MGI:3696435 +100036014 Psrs3 MGI:MGI:3697135 +100036015 Psrs7 MGI:MGI:3697139 +100036016 Vmmt4 MGI:MGI:3697192 +100036017 Vmmt8 MGI:MGI:3697196 +100036018 Vmmt13 MGI:MGI:3697201 +100036019 Vmmt16 MGI:MGI:3697204 +100036020 Imab6 MGI:MGI:3697631 +100036021 Ftm1 MGI:MGI:3697832 +100036022 Abfm2 MGI:MGI:3697833 +100036023 Mofp5 MGI:MGI:3697836 +100036024 Rfpw5 MGI:MGI:3697841 +100036025 Gf1 MGI:MGI:3697849 +100036026 Bmd28 MGI:MGI:3697856 +100036027 Bmd33 MGI:MGI:3697858 +100036028 Pbft3 MGI:MGI:3697862 +100036029 Gf2 MGI:MGI:3697865 +100036030 Ba4 MGI:MGI:3698437 +100036031 Bmc8 MGI:MGI:3698439 +100036032 Lbm15 MGI:MGI:3698444 +100036033 Lbm13 MGI:MGI:3698450 +100036034 Gf3 MGI:MGI:3698456 +100036035 Ftm4 MGI:MGI:3698460 +100036036 Bmc6 MGI:MGI:3698465 +100036037 Bmc11 MGI:MGI:3698466 +100036038 Wg6 MGI:MGI:3698534 +100036039 Kwq15 MGI:MGI:3698539 +100036040 Bdlnq7 MGI:MGI:3698542 +100036041 Feml4 MGI:MGI:3698549 +100036042 Mfat2 MGI:MGI:3699286 +100036043 Mfat7 MGI:MGI:3699297 +100036044 Nhq1 MGI:MGI:3699373 +100036045 Sox10m3 MGI:MGI:3511473 +100036046 Bmd38 MGI:MGI:3699720 +100036047 Bmrbc2 MGI:MGI:3699856 +100036048 Blacv1 MGI:MGI:3700015 +100036049 Pbw2 MGI:MGI:2152019 +100036050 Etmr MGI:MGI:2387322 +100036051 Oss2 MGI:MGI:2389038 +100036052 Lith11 MGI:MGI:2653456 +100036053 Ath21 MGI:MGI:2656118 +100036054 Hbnr2 MGI:MGI:2660591 +100036055 Hrq1 MGI:MGI:2662841 +100036056 Psl2 MGI:MGI:2664117 +100036057 Tbbmd1 MGI:MGI:2668914 +100036058 Cfsw3 MGI:MGI:2670601 +100036059 T2dm1sa MGI:MGI:4418285 +100036060 Scc13 MGI:MGI:2680975 +100036061 Abbp3 MGI:MGI:3026893 +100036062 Fibrs1 MGI:MGI:3036577 +100036063 Ffal1 MGI:MGI:3036906 +100036064 Cocia13 MGI:MGI:3040204 +100036065 Elsgp2 MGI:MGI:3040462 +100036066 Lvrq7 MGI:MGI:3042917 +100036067 Epfq3 MGI:MGI:3042928 +100036068 Vtbt13 MGI:MGI:3045055 +100036069 Gbrln MGI:MGI:3047352 +100036070 Hipp5 MGI:MGI:3052079 +100036071 Nrtim2 MGI:MGI:3053624 +100036072 Mp53d2 MGI:MGI:3054217 +100036074 Skmw9 MGI:MGI:3510243 +100036075 Grwtj4 MGI:MGI:3510722 +100036076 Fmgty2 MGI:MGI:3512799 +100036077 Fmgty6 MGI:MGI:3512919 +100036078 Hlpx MGI:MGI:3521873 +100036079 Arigg5 MGI:MGI:3524760 +100036080 Idd23 MGI:MGI:3525329 +100036081 W10q3 MGI:MGI:3526923 +100036082 W6q4 MGI:MGI:3526936 +100036083 Lgaq5 MGI:MGI:3527501 +100036084 Lgaq1 MGI:MGI:3527563 +100036085 Manln15 MGI:MGI:3528320 +100036086 Nba5 MGI:MGI:3529863 +100036087 Obwq2 MGI:MGI:3531517 +100036088 Adip13 MGI:MGI:3531538 +100036089 Gct6 MGI:MGI:3574516 +100036090 Erars2 MGI:MGI:3577036 +100036091 Scpro11 MGI:MGI:3578831 +100036092 Bntq14 MGI:MGI:3578895 +100036093 Avptaq3 MGI:MGI:3580596 +100036094 Igan1 MGI:MGI:3581245 +100036095 Ptnu1 MGI:MGI:3583624 +100036096 Cplaq10 MGI:MGI:3588345 +100036097 Vacq5 MGI:MGI:3590250 +100036098 Marq4 MGI:MGI:3590513 +100036099 Lmrq5 MGI:MGI:3603270 +100036100 Mfiq2 MGI:MGI:3604748 +100036101 Spnw2 MGI:MGI:3604984 +100036102 Mtxe6 MGI:MGI:3606293 +100036103 Sdtq2 MGI:MGI:3607512 +100036104 Mohg2 MGI:MGI:3607562 +100036105 Impbw1 MGI:MGI:3610975 +100036106 Cmn1 MGI:MGI:3612500 +100036107 Chlq5 MGI:MGI:3613646 +100036108 Hdlq47 MGI:MGI:3618618 +100036109 Pgis2 MGI:MGI:3622195 +100036110 Scgq1 MGI:MGI:3624655 +100036111 Lmr19 MGI:MGI:3625869 +100036112 Fatpad4 MGI:MGI:3629112 +100036113 Nilac5 MGI:MGI:3629973 +100036114 Org1 MGI:MGI:3639906 +100036115 Bod2 MGI:MGI:3639910 +100036116 Bod11 MGI:MGI:3639986 +100036117 Skmw14 MGI:MGI:3640572 +100036118 Etax10 MGI:MGI:3652360 +100036119 Spmd2 MGI:MGI:3654116 +100036120 Mohg5 MGI:MGI:3656278 +100036121 Mskt7 MGI:MGI:3663608 +100036122 Blct5 MGI:MGI:3663648 +100036123 Dbm3 MGI:MGI:3664268 +100036124 Chlq11 MGI:MGI:3665177 +100036125 Slms1 MGI:MGI:3688604 +100036126 Nhil2 MGI:MGI:3691598 +100036127 Dbsq3 MGI:MGI:3693575 +100036128 Eac5 MGI:MGI:3693657 +100036129 Mlrrq MGI:MGI:3696562 +100036130 Vmmt10 MGI:MGI:3697198 +100036131 Mfat3 MGI:MGI:3699287 +100036132 Nidd1k MGI:MGI:2387101 +100036133 Ath19 MGI:MGI:2451365 +100036134 Lmr7 MGI:MGI:2656513 +100036135 Lgth4 MGI:MGI:2656815 +100036136 Skts13 MGI:MGI:2664701 +100036137 Tbbmd3 MGI:MGI:2668916 +100036138 Pgia26 MGI:MGI:2675276 +100036139 Hstx1 MGI:MGI:3028213 +100036140 Moo1 MGI:MGI:3037100 +100036141 Cocia14 MGI:MGI:3040205 +100036142 Epfq4 MGI:MGI:3042915 +100036143 Vtbt17 MGI:MGI:3045059 +100036144 Angfq2 MGI:MGI:3046556 +100036145 Brmth7 MGI:MGI:3053763 +100036146 Bwnd5wk3 MGI:MGI:3497854 +100036147 Lprq3 MGI:MGI:3511878 +100036148 Fmgty4 MGI:MGI:3512916 +100036150 Scq1 MGI:MGI:3521948 +100036151 Pnhdlc2 MGI:MGI:3525296 +100036152 Lgq4 MGI:MGI:3526907 +100036153 Egq7 MGI:MGI:3527497 +100036154 W3q6 MGI:MGI:3527647 +100036155 Obwq1 MGI:MGI:3531516 +100036156 Gpdc1 MGI:MGI:3573760 +100036157 Lith22 MGI:MGI:3577216 +100036158 Sphsr1 MGI:MGI:3579342 +100036159 Pbmd2 MGI:MGI:3581230 +100036160 Pbwg16 MGI:MGI:3589176 +100036161 Vacq7 MGI:MGI:3590252 +100036162 Abfp1 MGI:MGI:3604962 +100036163 Spnw6 MGI:MGI:3604988 +100036164 Hdlq38 MGI:MGI:3607078 +100036165 Ltxs3 MGI:MGI:3609214 +100036166 Pscr3 MGI:MGI:3617621 +100036167 Chcmq2 MGI:MGI:3622218 +100036168 Fatpad2 MGI:MGI:3629107 +100036169 Elcs1 MGI:MGI:3639714 +100036170 Bod8 MGI:MGI:3639972 +100036171 Alpq2 MGI:MGI:3652894 +100036172 Appd2 MGI:MGI:3663091 +100036173 Imct2 MGI:MGI:3663656 +100036174 Bczr1 MGI:MGI:3688574 +100036175 Hfem1 MGI:MGI:3692625 +100036176 Ity7 MGI:MGI:3694093 +100036177 Vmmt5 MGI:MGI:3697193 +100036178 Bw27 MGI:MGI:3697823 +100036179 Pbft1 MGI:MGI:3697846 +100036180 Bmd35 MGI:MGI:3698463 +100036181 Fatmq1 MGI:MGI:3698543 +100036182 Tshp14 MGI:MGI:2386706 +100036183 Lmr13 MGI:MGI:2656546 +100036184 Pbwg2 MGI:MGI:3035958 +100036185 Lptl2 MGI:MGI:3046326 +100036186 Ahl3 MGI:MGI:3514038 +100036187 Obsty4 MGI:MGI:3525638 +100036188 Egaq3 MGI:MGI:3527655 +100036189 Wbcq5 MGI:MGI:3574409 +100036190 Nsila4 MGI:MGI:3580544 +100036191 Ses1b MGI:MGI:3588683 +100036192 Abfw5 MGI:MGI:3604971 +100036193 Brml3 MGI:MGI:3694906 +100036194 Chldq4 MGI:MGI:3699372 +100036195 Pbbcp2 MGI:MGI:1930820 +100036196 Ses4 MGI:MGI:2137368 +100036197 Cdcs8 MGI:MGI:2159143 +100036198 Ssial4 MGI:MGI:2385536 +100036199 Tshp13 MGI:MGI:2386705 +100036200 Paam1 MGI:MGI:2387302 +100036201 Sluc27 MGI:MGI:2387372 +100036202 Oss1 MGI:MGI:2389037 +100036203 Asbb2 MGI:MGI:2389189 +100036204 Pbrgcsf1 MGI:MGI:2446642 +100036206 Tapr MGI:MGI:2654004 +100036207 Pgia20 MGI:MGI:2656522 +100036208 Cia14 MGI:MGI:2656530 +100036209 Lbm6 MGI:MGI:2656807 +100036210 Musz4 MGI:MGI:2660616 +100036211 Spir1 MGI:MGI:2661190 +100036212 Pfibs2 MGI:MGI:2661904 +100036213 Mndl1 MGI:MGI:2663054 +100036214 Trmq2 MGI:MGI:2664280 +100036215 Ltsd1 MGI:MGI:2664838 +100036216 Pcyts3 MGI:MGI:2665064 +100036217 Tbbmd5 MGI:MGI:2668918 +100036218 Fcsa1 MGI:MGI:2668935 +100036219 Mbis4 MGI:MGI:2669464 +100036220 Tmevd8 MGI:MGI:2669610 +100036221 Cfid MGI:MGI:2670597 +100036222 Splrn1 MGI:MGI:2670602 +100036223 Ofca4 MGI:MGI:2670608 +100036224 Gbvq1 MGI:MGI:2675426 +100036225 Capsq4 MGI:MGI:2680362 +100036226 Aevm1 MGI:MGI:2680906 +100036227 Hrl MGI:MGI:2682423 +100036228 Hbnr4 MGI:MGI:2687238 +100036229 Hbnr5 MGI:MGI:2687239 +100036230 Tb2r1 MGI:MGI:3821865 +100036231 Nbwa2 MGI:MGI:3033345 +100036232 Pbwg10 MGI:MGI:3035968 +100036233 Vmbic9 MGI:MGI:3036607 +100036234 Aorls1 MGI:MGI:3036904 +100036235 Cia5b MGI:MGI:3038266 +100036236 Cia29 MGI:MGI:3039461 +100036237 Cocia11 MGI:MGI:3040202 +100036238 Eae32 MGI:MGI:3040307 +100036239 Eae31 MGI:MGI:3040399 +100036240 Aabpr MGI:MGI:3042396 +100036241 Epfq2 MGI:MGI:3042893 +100036242 Kidpq1 MGI:MGI:3042916 +100036243 Epfpq3 MGI:MGI:3042923 +100036244 Mmtp1 MGI:MGI:3043750 +100036245 Ethm3 MGI:MGI:3044650 +100036246 Vtbt6 MGI:MGI:3045048 +100036247 Vtbt14 MGI:MGI:3045056 +100036248 Pfat3 MGI:MGI:3046215 +100036249 Gluchos2 MGI:MGI:3046234 +100036250 Hcif1 MGI:MGI:3046663 +100036251 Si5lq5 MGI:MGI:3047365 +100036252 Heal12 MGI:MGI:3051548 +100036253 Apsic1 MGI:MGI:3053409 +100036254 Brmth1 MGI:MGI:3053757 +100036255 Brmth6 MGI:MGI:3053762 +100036256 Mdmsc5 MGI:MGI:3054069 +100036257 Bmd22 MGI:MGI:3054101 +100036258 Tgct5 MGI:MGI:3054749 +100036259 Hrq5 MGI:MGI:3057296 +100036264 Bwnd5wk7 MGI:MGI:3510182 +100036265 Skmw11 MGI:MGI:3510245 +100036266 Grwtj1 MGI:MGI:3510719 +100036267 Bmch6 MGI:MGI:3511311 +100036268 Espq1 MGI:MGI:3512157 +100036269 Estoq1 MGI:MGI:3512161 +100036270 Mhstq1 MGI:MGI:3512245 +100036271 Fmgty9 MGI:MGI:3512926 +100036272 Salpa1 MGI:MGI:3514272 +100036273 Hlbsb2 MGI:MGI:3521775 +100036274 Elpfm MGI:MGI:3521869 +100036275 Arigm3 MGI:MGI:3524751 +100036276 Arigg1 MGI:MGI:3524756 +100036277 Eae27 MGI:MGI:3524867 +100036278 Rthyd3 MGI:MGI:3525121 +100036279 Pnhdlc4 MGI:MGI:3525298 +100036280 Ceat1 MGI:MGI:3526118 +100036281 W6q2 MGI:MGI:3526914 +100036282 Tailq4 MGI:MGI:3526920 +100036283 W10q4 MGI:MGI:3526927 +100036284 W6q5 MGI:MGI:3526939 +100036285 Tailaq2 MGI:MGI:3526957 +100036286 W3q4 MGI:MGI:3527560 +100036287 Tailq1 MGI:MGI:3527569 +100036288 Tailq6 MGI:MGI:3527646 +100036289 Egaq2 MGI:MGI:3527653 +100036290 Mbsyd MGI:MGI:3528032 +100036291 Manln9 MGI:MGI:3528314 +100036292 Cinda4 MGI:MGI:3529468 +100036293 Eae39 MGI:MGI:3530105 +100036294 Eae35 MGI:MGI:3530894 +100036295 Nwa2 MGI:MGI:3531137 +100036296 Obwq3 MGI:MGI:3531518 +100036297 Bwtq11 MGI:MGI:3531524 +100036298 Gpdc3 MGI:MGI:3573762 +100036299 Mstat5ab MGI:MGI:3574340 +100036300 Wbcq4 MGI:MGI:3574408 +100036301 Ibdq1 MGI:MGI:3574489 +100036302 Tcdel2 MGI:MGI:3575697 +100036303 Lith21 MGI:MGI:3577215 +100036304 Scpro9 MGI:MGI:3578829 +100036305 Bntq4 MGI:MGI:3578877 +100036306 Bntq16 MGI:MGI:3578898 +100036307 Drsi MGI:MGI:3579880 +100036308 Rafar MGI:MGI:3580535 +100036309 Nsila3 MGI:MGI:3580543 +100036310 Nsila10 MGI:MGI:3580550 +100036311 Crhr1taq3 MGI:MGI:3580599 +100036312 Cplaq8 MGI:MGI:3581253 +100036313 Gnf3 MGI:MGI:3582468 +100036314 Mord3 MGI:MGI:3583101 +100036315 Salpa3 MGI:MGI:3583888 +100036316 Htas6 MGI:MGI:3587073 +100036317 Cplaq9 MGI:MGI:3588344 +100036318 Artmd2 MGI:MGI:3588384 +100036319 Ses9 MGI:MGI:3588677 +100036320 Pbwg17 MGI:MGI:3589177 +100036321 Vacq2 MGI:MGI:3590247 +100036322 Tsiq2 MGI:MGI:3590287 +100036323 Marq3 MGI:MGI:3590512 +100036324 Mpdk4 MGI:MGI:3603223 +100036325 Mpdk7 MGI:MGI:3603226 +100036326 Imraq3 MGI:MGI:3603759 +100036327 Mlepq1 MGI:MGI:3604739 +100036328 Mfi5q1 MGI:MGI:3604742 +100036329 Abfp3 MGI:MGI:3604964 +100036330 Abfw6 MGI:MGI:3604972 +100036331 Bmgr3 MGI:MGI:3606053 +100036332 Ebmgr1 MGI:MGI:3606055 +100036333 Cfmq2 MGI:MGI:3606274 +100036334 Iba6 MGI:MGI:3606303 +100036335 Idd21.2 MGI:MGI:3606916 +100036336 Sdtq1 MGI:MGI:3607511 +100036337 Sdtq8 MGI:MGI:3607518 +100036338 Wght5 MGI:MGI:3608831 +100036339 Dvs2 MGI:MGI:3609562 +100036340 Bw23 MGI:MGI:3610973 +100036341 Qbis3 MGI:MGI:3612489 +100036342 Sbcf MGI:MGI:3612944 +100036343 Ascla4 MGI:MGI:3613543 +100036344 Chlq2 MGI:MGI:3613642 +100036345 Hdlq48 MGI:MGI:3618619 +100036346 Eae40 MGI:MGI:3619138 +100036347 Asdq6 MGI:MGI:3619563 +100036348 Hctq1 MGI:MGI:3622212 +100036349 Mcvq2 MGI:MGI:3622215 +100036350 Bodwt1 MGI:MGI:3624640 +100036351 Scgq3 MGI:MGI:3624657 +100036352 Scgq5 MGI:MGI:3624670 +100036353 Pbat2 MGI:MGI:3625038 +100036355 Orgwt8 MGI:MGI:3629119 +100036356 Ntta1 MGI:MGI:3629792 +100036357 Nilac3 MGI:MGI:3629970 +100036358 Nilac9 MGI:MGI:3629979 +100036359 Elads1 MGI:MGI:3639706 +100036360 Lbn2 MGI:MGI:3639905 +100036361 Lbn8 MGI:MGI:3639963 +100036362 Bod7 MGI:MGI:3639971 +100036363 Pregq3 MGI:MGI:3640535 +100036364 Skmw15 MGI:MGI:3640573 +100036365 Etax5 MGI:MGI:3641464 +100036366 Etax9 MGI:MGI:3652358 +100036367 Advh2 MGI:MGI:3653385 +100036368 Bfsz2 MGI:MGI:3654070 +100036369 Raml1 MGI:MGI:3655630 +100036370 Ibdq2 MGI:MGI:3655686 +100036371 Clas4 MGI:MGI:3662680 +100036372 Appd1 MGI:MGI:3663090 +100036373 Blct1 MGI:MGI:3663638 +100036374 Erph1 MGI:MGI:3663644 +100036375 Mpcp1 MGI:MGI:3664221 +100036376 Mpcp7 MGI:MGI:3664227 +100036377 Mpcp11 MGI:MGI:3664231 +100036378 Chlq14 MGI:MGI:3665182 +100036379 Hmtb1 MGI:MGI:3688273 +100036380 Elda2 MGI:MGI:3688589 +100036381 Elda3 MGI:MGI:3689515 +100036382 Lore11 MGI:MGI:3689527 +100036383 Msts3 MGI:MGI:3690348 +100036384 Nhil5 MGI:MGI:3691601 +100036385 Fcs1 MGI:MGI:3691665 +100036386 Ctrq2 MGI:MGI:3692642 +100036387 Dbsq5 MGI:MGI:3693577 +100036388 Eac4 MGI:MGI:3693656 +100036389 Actre6 MGI:MGI:3694112 +100036390 Brml4 MGI:MGI:3694907 +100036391 Bmd26 MGI:MGI:3694913 +100036392 Dshv1 MGI:MGI:3696434 +100036393 Char2a MGI:MGI:3697100 +100036394 Vmmt1 MGI:MGI:3697189 +100036395 Vmmt7 MGI:MGI:3697195 +100036396 Vmmt11 MGI:MGI:3697199 +100036397 Vmmt14 MGI:MGI:3697202 +100036398 Imab7 MGI:MGI:3697629 +100036399 Bw32 MGI:MGI:3697828 +100036400 Mofp1 MGI:MGI:3697835 +100036401 Bmc7 MGI:MGI:3697839 +100036402 Ftm5 MGI:MGI:3697845 +100036403 Rfpw2 MGI:MGI:3697851 +100036404 Bmd36 MGI:MGI:3697859 +100036405 Rfpw3 MGI:MGI:3697867 +100036406 Bmc9 MGI:MGI:3698448 +100036407 Ftm3 MGI:MGI:3698459 +100036408 Bmd37 MGI:MGI:3698464 +100036409 Bmd34 MGI:MGI:3698470 +100036410 Wg7 MGI:MGI:3698535 +100036411 Tcq2 MGI:MGI:3698546 +100036412 Gfpq1 MGI:MGI:3698550 +100036413 Mfat5 MGI:MGI:3699292 +100036414 Mfat8 MGI:MGI:3699299 +100036415 Sox10m5 MGI:MGI:3511475 +100036416 Bmrbc3 MGI:MGI:3699857 +100036417 Fembrs4 MGI:MGI:1891229 +100036418 Gvhd5 MGI:MGI:2386606 +100036419 Pbrgcsf2 MGI:MGI:2446643 +100036420 Pgia21 MGI:MGI:2656523 +100036421 Pcd4ts3 MGI:MGI:2661282 +100036422 Hwq1 MGI:MGI:2662846 +100036423 Ltsd6 MGI:MGI:2664843 +100036424 Tmevd9 MGI:MGI:2669611 +100036425 Capsq2 MGI:MGI:2680360 +100036426 Hrtfm4 MGI:MGI:2686941 +100036427 Vmbic6 MGI:MGI:3036604 +100036428 Cia26 MGI:MGI:3038904 +100036429 Pwatq1 MGI:MGI:3042877 +100036430 Ethm2 MGI:MGI:3044649 +100036431 wrmod1 MGI:MGI:3045881 +100036432 Dmyaq3 MGI:MGI:3051265 +100036433 Brmth9 MGI:MGI:3053765 +100036436 Popoa MGI:MGI:3511869 +100036437 Estoq3 MGI:MGI:3512164 +100036438 Hlbsb1 MGI:MGI:3521774 +100036439 Cmcs MGI:MGI:3522313 +100036440 Rthyd2 MGI:MGI:3525120 +100036441 W10q9 MGI:MGI:3526911 +100036442 W3q13 MGI:MGI:3526946 +100036443 Tailaq3 MGI:MGI:3527617 +100036444 Stzid MGI:MGI:3528282 +100036445 Eae37 MGI:MGI:3530897 +100036446 Dice1a MGI:MGI:3573894 +100036447 Scpro7 MGI:MGI:3578827 +100036448 Idd16.1 MGI:MGI:3579885 +100036449 Gnf4 MGI:MGI:3582469 +100036450 Htas1 MGI:MGI:3587071 +100036451 Pbwg22 MGI:MGI:3589182 +100036452 Mpdk3 MGI:MGI:3603222 +100036453 Tmc1m2 MGI:MGI:3604735 +100036454 Btts MGI:MGI:3606253 +100036455 Idd21.1 MGI:MGI:3606918 +100036456 Pltq2 MGI:MGI:3609320 +100036457 Ascla3 MGI:MGI:3613542 +100036458 Bmd1b MGI:MGI:3619534 +100036459 Mcvq3 MGI:MGI:3622216 +100036460 Pbat1 MGI:MGI:3625037 +100036462 Elads2 MGI:MGI:3639707 +100036463 Org7 MGI:MGI:3639967 +100036464 Etax4 MGI:MGI:3641460 +100036465 Advh1 MGI:MGI:3653384 +100036466 Azdm4 MGI:MGI:3663049 +100036467 Mpcp5 MGI:MGI:3664225 +100036468 Hmtb2 MGI:MGI:3688274 +100036469 Wtlr4 MGI:MGI:3689542 +100036470 Fcs4 MGI:MGI:3691668 +100036471 Pstc2 MGI:MGI:3694915 +100036472 Vmmt3 MGI:MGI:3697191 +100036473 Vmmt19 MGI:MGI:3697207 +100036474 Pbrbc2 MGI:MGI:3699853 +100036475 Hfib1 MGI:MGI:2178324 +100036476 Asbb1 MGI:MGI:2389188 +100036477 Pfibs1 MGI:MGI:2661903 +100036478 Pcir3 MGI:MGI:2670126 +100036479 Scc14 MGI:MGI:2680976 +100036480 Fibrs2 MGI:MGI:3036578 +100036481 Axtrb9 MGI:MGI:3041568 +100036482 Mmtp3 MGI:MGI:3043752 +100036483 Lnopy2 MGI:MGI:3052175 +100036484 Pymr MGI:MGI:3055094 +100036486 Ssta6 MGI:MGI:3510708 +100036487 Arigg3 MGI:MGI:3524758 +100036488 W3q9 MGI:MGI:3526928 +100036489 Manln7 MGI:MGI:3528312 +100036490 Stzid2 MGI:MGI:3529674 +100036491 Gct8 MGI:MGI:3574498 +100036492 Nsila6 MGI:MGI:3580546 +100036493 Imebt2 MGI:MGI:3583086 +100036494 Htas7 MGI:MGI:3587074 +100036495 Idd26 MGI:MGI:3603298 +100036496 Mtxe4 MGI:MGI:3606291 +100036497 Qbis4 MGI:MGI:3612490 +100036498 Miju MGI:MGI:3619552 +100036499 Mancq2 MGI:MGI:3624755 +100036500 Nilac1 MGI:MGI:3629965 +100036501 Skmw18 MGI:MGI:3640576 +100036502 Raml3 MGI:MGI:3655632 +100036503 Chlq9 MGI:MGI:3665175 +100036504 Nashs2 MGI:MGI:3690343 +100036505 Amdt2 MGI:MGI:3695446 +100036506 Vmmt20 MGI:MGI:3697210 +100036507 Rfpw7 MGI:MGI:3697869 +100036508 Tglq2 MGI:MGI:3699368 +100036509 Fcsa5 MGI:MGI:2668939 +100036510 Trmq5 MGI:MGI:3042195 +100036511 Tilss2 MGI:MGI:3055199 +100036513 LOC100036513 - +100036518 Vmn1r223 MGI:MGI:3649245|Ensembl:ENSMUSG00000069280|Vega:OTTMUSG00000000541 +100036520 Gata5os MGI:MGI:3650386|Ensembl:ENSMUSG00000056061 +100036521 Umad1 MGI:MGI:3840148|Ensembl:ENSMUSG00000089862|Ensembl:ENSMUSG00000107705|Vega:OTTMUSG00000029336|Vega:OTTMUSG00000056945 +100036523 Gm16982 MGI:MGI:4439906|Ensembl:ENSMUSG00000097170 +100036526 Gm9887 MGI:MGI:3642578 +100036528 LOC100036528 - +100036530 LOC100036530 - +100036533 Gm9934 MGI:MGI:3641747 +100036535 Gm9913 MGI:MGI:3642395 +100036537 Gm11149 MGI:MGI:3642683|Ensembl:ENSMUSG00000079564 +100036538 BC028777 MGI:MGI:3642753 +100036539 Gm13999 MGI:MGI:3651905 +100036540 LOC100036540 - +100036541 Gm9744 MGI:MGI:3642478 +100036543 Gm9983 MGI:MGI:3642849 +100036544 D630002J18Rik MGI:MGI:3642398 +100036559 Pis1 MGI:MGI:3700920 +100036560 Arrd4 MGI:MGI:3700830 +100036561 Pis2 MGI:MGI:3700921 +100036568 Gm3373 MGI:MGI:3781551 +100036569 Gm16525 MGI:MGI:4361006 +100036572 LOC100036572 - +100036573 Gm13066 MGI:MGI:3701131 +100036741 Fbtq2 MGI:MGI:3701621 +100036742 Fbtq3 MGI:MGI:3701622 +100036743 Fbtq5 MGI:MGI:3701624 +100036744 Fbtq6 MGI:MGI:3701625 +100036745 Fbtq8 MGI:MGI:3701627 +100036746 Mlca2 MGI:MGI:3701677 +100036748 Mlca5 MGI:MGI:3701680 +100036749 Fbtq1 MGI:MGI:3701620 +100036750 Sle19 MGI:MGI:3701658 +100036751 Fbtq4 MGI:MGI:3701623 +100036752 Fbtq7 MGI:MGI:3701626 +100036753 Mlca1 MGI:MGI:3701676 +100036754 Mlca4 MGI:MGI:3701679 +100036768 Gm11696 MGI:MGI:3701776|Ensembl:ENSMUSG00000056687 +100037255 Idd4.3 MGI:MGI:3702132 +100037256 Il4ppq MGI:MGI:3702119 +100037258 Dnajc3 MGI:MGI:107373|Ensembl:ENSMUSG00000022136 +100037260 9430060I03Rik MGI:MGI:3702484|Ensembl:ENSMUSG00000100632 +100037262 Gm12359 MGI:MGI:3702436|Ensembl:ENSMUSG00000075576 +100037263 4921516A02Rik MGI:MGI:3696861 +100037278 Fam129c MGI:MGI:3686743|Ensembl:ENSMUSG00000043243|Vega:OTTMUSG00000033939 +100037281 Gm10589 MGI:MGI:3641651 +100037282 Rsph3b MGI:MGI:3630308|Ensembl:ENSMUSG00000023806 +100037283 Rnaset2a MGI:MGI:1915445|Ensembl:ENSMUSG00000095687 +100037297 5430403G19Rik MGI:MGI:2679522 +100037396 D030047H15Rik MGI:MGI:3698136|Ensembl:ENSMUSG00000085886 +100037410 Dbmc1 MGI:MGI:3702976 +100037411 Dbmc2 MGI:MGI:3702977 +100037412 Dbmc3 MGI:MGI:3702978 +100037413 Gm13274 MGI:MGI:3649443 +100038346 B930046K06Rik MGI:MGI:3697818 +100038347 Fam174b MGI:MGI:3698178|Ensembl:ENSMUSG00000078670|Vega:OTTMUSG00000058373 +100038349 Gm10862 MGI:MGI:3641622 +100038351 Gm10792 MGI:MGI:3641647 +100038352 Gm10802 MGI:MGI:3641658 +100038353 Gm10532 MGI:MGI:3641671|Ensembl:ENSMUSG00000097712 +100038354 G730003C15Rik MGI:MGI:3641700 +100038355 Runx2os1 MGI:MGI:3641707 +100038356 Gm15612 MGI:MGI:3641714|Ensembl:ENSMUSG00000085828 +100038357 Gm10856 MGI:MGI:3641730 +100038358 Gm10857 MGI:MGI:3641733|Ensembl:ENSMUSG00000102887 +100038359 Gm10685 MGI:MGI:3641752 +100038360 Gm10803 MGI:MGI:3641754 +100038361 Gm10723 MGI:MGI:3641783 +100038363 F630028O10Rik MGI:MGI:3641813|Ensembl:ENSMUSG00000078122 +100038364 Gm10836 MGI:MGI:3641831 +100038366 Gm10405 MGI:MGI:3641856 +100038367 Gm10513 MGI:MGI:3641888 +100038368 Gm10609 MGI:MGI:3641912 +100038369 F630201L12Rik MGI:MGI:3641915 +100038370 4932427H20Rik MGI:MGI:3641919 +100038371 Zfp389 MGI:MGI:3641940 +100038372 Gm10763 MGI:MGI:3641951 +100038373 Gm10062 MGI:MGI:3641967 +100038374 Gm10714 MGI:MGI:3641975|Ensembl:ENSMUSG00000074555 +100038375 Gm10531 MGI:MGI:3641983 +100038376 Gm10876 MGI:MGI:3641995 +100038377 Gm10750 MGI:MGI:3641996 +100038378 Gm10433 MGI:MGI:3642010|Ensembl:ENSMUSG00000072884 +100038380 Gm10837 MGI:MGI:3642026 +100038381 Gm10647 MGI:MGI:3642036 +100038382 Gm10648 MGI:MGI:3642037 +100038383 Gm10650 MGI:MGI:3642040 +100038384 Gm10610 MGI:MGI:3642045 +100038385 F830115B05Rik MGI:MGI:3642056 +100038387 Gm10473 MGI:MGI:3642088 +100038388 Gm10614 MGI:MGI:3642104 +100038389 Gm10286 MGI:MGI:3642117 +100038390 G730046D07Rik MGI:MGI:3642131 +100038391 Gm10287 MGI:MGI:3642138 +100038392 Gm10785 MGI:MGI:3642149|Ensembl:ENSMUSG00000085169 +100038393 Gm10183 MGI:MGI:3642155 +100038394 Gm10512 MGI:MGI:3642173 +100038395 1700061E17Rik MGI:MGI:3642196 +100038397 Gm44113 MGI:MGI:5690505 +100038399 Gm10579 MGI:MGI:3642230 +100038402 BC025933 MGI:MGI:3642287 +100038403 Gm10741 MGI:MGI:3642299 +100038405 Gm10827 MGI:MGI:3642321 +100038407 Gm10522 MGI:MGI:3642357 +100038410 Gm10536 MGI:MGI:3642440 +100038411 Gm15998 MGI:MGI:3802094 +100038412 Faddos MGI:MGI:3642460 +100038413 D130050E23Rik MGI:MGI:3642469 +100038414 Gm10735 MGI:MGI:3642476 +100038416 Gm10643 MGI:MGI:3642507 +100038417 Spink13 MGI:MGI:3642511|Ensembl:ENSMUSG00000073551|Vega:OTTMUSG00000049765 +100038418 Gm10701 MGI:MGI:3642532 +100038419 E330027M22Rik MGI:MGI:3642536 +100038420 Gm10624 MGI:MGI:3642550 +100038421 Gm10733 MGI:MGI:3642560 +100038424 Gm10604 MGI:MGI:3642593 +100038426 Gm10563 MGI:MGI:3642630 +100038427 Gm10652 MGI:MGI:3642648 +100038428 Gm10417 MGI:MGI:3642677 +100038429 Gm10505 MGI:MGI:3642687 +100038431 Gm10568 MGI:MGI:3642703 +100038433 9130213A22Rik MGI:MGI:3642718 +100038435 Gm10661 MGI:MGI:3642759 +100038436 Gm10503 MGI:MGI:3642784 +100038437 Gm10706 MGI:MGI:3642794 +100038438 Gm10372 MGI:MGI:3642804 +100038439 Gm10556 MGI:MGI:3642809|Ensembl:ENSMUSG00000097043 +100038440 Gm16508 MGI:MGI:3642810 +100038443 9330195I24Rik MGI:MGI:3642861 +100038444 Gm10472 MGI:MGI:3642883 +100038445 Gm10216 MGI:MGI:3642891 +100038447 Gm10729 MGI:MGI:3642905 +100038448 Gm10840 MGI:MGI:3642918 +100038449 Gm10755 MGI:MGI:3642924 +100038450 Gm12472 MGI:MGI:3649439 +100038452 Gm13372 MGI:MGI:3650806 +100038453 Gm12522 MGI:MGI:3651334|Ensembl:ENSMUSG00000074281 +100038454 Platr8 MGI:MGI:3652122|Ensembl:ENSMUSG00000063751 +100038455 Plast1a MGI:MGI:3703624 +100038456 Plast1b MGI:MGI:3703625 +100038457 Plast2a MGI:MGI:3703759 +100038458 Plast2b MGI:MGI:3703760 +100038459 Gm10831 MGI:MGI:3641619 +100038460 Gm10677 MGI:MGI:3641629 +100038462 Gm10641 MGI:MGI:3641696 +100038463 Gm10859 MGI:MGI:3641731 +100038464 Gm15441 MGI:MGI:3641753|Ensembl:ENSMUSG00000074398 +100038465 Gm10773 MGI:MGI:3641797 +100038466 Gm10854 MGI:MGI:3641821 +100038467 A630072L19Rik MGI:MGI:3641830 +100038468 Gm10684 MGI:MGI:3641851|Ensembl:ENSMUSG00000074385 +100038470 Gm10808 MGI:MGI:3641938 +100038472 Gm10469 MGI:MGI:3641993 +100038473 Gm10490 MGI:MGI:3642001 +100038474 K230015D01Rik MGI:MGI:3642019 +100038475 M5C1000I18Rik MGI:MGI:3642038 +100038476 Gm10457 MGI:MGI:3642070 +100038478 Gm10616 MGI:MGI:3642103 +100038479 Gm10787 MGI:MGI:3642150|Ensembl:ENSMUSG00000074919 +100038480 Gm10461 MGI:MGI:3642164 +100038481 Gm10510 MGI:MGI:3642174 +100038485 Gm10398 MGI:MGI:3642254 +100038486 Gm10742 MGI:MGI:3642301 +100038487 Gm10629 MGI:MGI:3642307 +100038489 Apela MGI:MGI:3642370|Ensembl:ENSMUSG00000079042|Vega:OTTMUSG00000032906 +100038490 G370062D05Rik MGI:MGI:3642425 +100038492 F630048H11Rik MGI:MGI:3642463 +100038493 Gm13582 MGI:MGI:3642495|Ensembl:ENSMUSG00000075325 +100038494 Gm10782 MGI:MGI:3642506 +100038496 Gm10655 MGI:MGI:3642575 +100038497 Gm10603 MGI:MGI:3642592 +100038498 Gm10447 MGI:MGI:3642647 +100038501 Gm10383 MGI:MGI:3642700 +100038502 G730007D18Rik MGI:MGI:3642709 +100038503 Gm10484 MGI:MGI:3642756 +100038504 Gm10369 MGI:MGI:3642774 +100038505 Gm10523 MGI:MGI:3642790 +100038506 Gm10873 MGI:MGI:3642812 +100038508 Gm10797 MGI:MGI:3642860 +100038509 Gm10544 MGI:MGI:3642892 +100038512 Gm12542 MGI:MGI:3651424 +100038513 Gm14149 MGI:MGI:3651549 +100038514 Gm11837 MGI:MGI:3702175 +100038516 Gm10640 MGI:MGI:3648835|Ensembl:ENSMUSG00000100985 +100038517 Plast1 MGI:MGI:3703758 +100038518 Plast3 MGI:MGI:3703761 +100038519 Gm9900 MGI:MGI:3641618 +100038520 Gm10830 MGI:MGI:3641625 +100038521 Gm10683 MGI:MGI:3641650 +100038522 Dnmt3aos MGI:MGI:3641689|Ensembl:ENSMUSG00000073242 +100038524 Gm10858 MGI:MGI:3641732 +100038525 Gm10804 MGI:MGI:3641755|Ensembl:ENSMUSG00000075025 +100038526 Gm10560 MGI:MGI:3641794 +100038528 Gm10851 MGI:MGI:3641824 +100038529 Gm10765 MGI:MGI:3641852 +100038531 D030062O11Rik MGI:MGI:3641918 +100038532 Gm10822 MGI:MGI:3641955 +100038534 7120482A17Rik MGI:MGI:3641992 +100038536 G530012D18Rik MGI:MGI:3642025 +100038537 Gm16503 MGI:MGI:3642127 +100038538 Gm10767 MGI:MGI:3642136|Ensembl:ENSMUSG00000074826|Vega:OTTMUSG00000037038 +100038541 Gm10554 MGI:MGI:3642177 +100038542 Gm10725 MGI:MGI:3642190 +100038543 Gm10832 MGI:MGI:3642210 +100038545 Gm10745 MGI:MGI:3642274|Ensembl:ENSMUSG00000104015 +100038546 Gm10743 MGI:MGI:3642302 +100038547 Gm10815 MGI:MGI:3642330 +100038548 Gm10521 MGI:MGI:3642358 +100038549 Gm10779 MGI:MGI:3642421 +100038550 Gm10703 MGI:MGI:3642447 +100038551 Gm10757 MGI:MGI:3642462 +100038552 4732463B04Rik MGI:MGI:3642483 +100038554 Gm15348 MGI:MGI:3642533|Ensembl:ENSMUSG00000074469 +100038555 Gm10578 MGI:MGI:3642555|Ensembl:ENSMUSG00000109722 +100038556 Gm10445 MGI:MGI:3642570|Ensembl:ENSMUSG00000107797 +100038557 Gm10605 MGI:MGI:3642596 +100038558 Gm10752 MGI:MGI:3642645 +100038559 Gm10673 MGI:MGI:3642656 +100038560 Gm10687 MGI:MGI:3642689 +100038561 B230104I21Rik MGI:MGI:3642713 +100038562 Gm10869 MGI:MGI:3642738 +100038563 Gm10295 MGI:MGI:3642770 +100038564 Gm10524 MGI:MGI:3642791 +100038565 Gm10871 MGI:MGI:3642814 +100038566 Gm10658 MGI:MGI:3642856 +100038568 Gm10483 MGI:MGI:3642894 +100038569 Gm10558 MGI:MGI:3642906 +100038570 Prcd MGI:MGI:3649529|Ensembl:ENSMUSG00000075410 +100038571 Gm12863 MGI:MGI:3651212|Ensembl:ENSMUSG00000073765 +100038572 Gm12000 MGI:MGI:3651524 +100038573 Gm10864 MGI:MGI:3641624 +100038574 Gm10415 MGI:MGI:3641661|Ensembl:ENSMUSG00000107623 +100038575 Gm10635 MGI:MGI:3641740|Ensembl:ENSMUSG00000111765 +100038576 F830112A20Rik MGI:MGI:3641781 +100038577 Gm10790 MGI:MGI:3641845|Ensembl:ENSMUSG00000113856 +100038578 Gm10848 MGI:MGI:3641917 +100038579 C730037M02Rik MGI:MGI:3641948 +100038580 6820445E23Rik MGI:MGI:3641990 +100038581 Gm10838 MGI:MGI:3642027 +100038582 Gm10824 MGI:MGI:3642049 +100038583 Gm10632 MGI:MGI:3642106 +100038584 Gm14812 MGI:MGI:3642165|Ensembl:ENSMUSG00000073051 +100038586 Gm10330 MGI:MGI:3642221 +100038587 Gm10278 MGI:MGI:3642246 +100038589 Gm10744 MGI:MGI:3642360 +100038590 Gm10535 MGI:MGI:3642442 +100038591 F420014N23Rik MGI:MGI:3642477|Ensembl:ENSMUSG00000097331 +100038592 Gm10385 MGI:MGI:3642705 +100038594 Gm10370 MGI:MGI:3642773 +100038595 Gm16287 MGI:MGI:3650322|Ensembl:ENSMUSG00000073739 +100038596 Gm10435 MGI:MGI:3642820 +100038597 A130057D12Rik MGI:MGI:3642847 +100038598 Gm10386 MGI:MGI:3642888 +100038599 Gm10710 MGI:MGI:3642896|Ensembl:ENSMUSG00000074517 +100038600 Gm11529 MGI:MGI:3649352 +100038601 Gm11691 MGI:MGI:3652328 +100038602 Gm10865 MGI:MGI:3641626 +100038604 3426406K10Rik MGI:MGI:3641679 +100038605 E030047D23Rik MGI:MGI:3641710 +100038606 Gm10829 MGI:MGI:3641721 +100038607 Gm10636 MGI:MGI:3641739|Ensembl:ENSMUSG00000105602 +100038608 Gm10389 MGI:MGI:3641773 +100038609 Gm10441 MGI:MGI:3641801 +100038610 Gm10747 MGI:MGI:3641810 +100038611 Gm10852 MGI:MGI:3641823 +100038612 Gm10682 MGI:MGI:3641844 +100038613 F830212C03Rik MGI:MGI:3641876 +100038614 Gm10791 MGI:MGI:3641949 +100038615 D230041D01Rik MGI:MGI:3641960 +100038616 Gm14636 MGI:MGI:3641976 +100038617 Gm10466 MGI:MGI:3641991|Ensembl:ENSMUSG00000073103 +100038618 Gm10847 MGI:MGI:3642004 +100038620 Gm10631 MGI:MGI:3642022 +100038621 Gm10839 MGI:MGI:3642029 +100038622 Gm10646 MGI:MGI:3642039 +100038623 Gm10823 MGI:MGI:3642050 +100038624 Gm10459 MGI:MGI:3642067 +100038625 Gm10846 MGI:MGI:3642097 +100038626 5830462I19Rik MGI:MGI:3642105 +100038627 F630042J09Rik MGI:MGI:3642133 +100038628 Gm10768 MGI:MGI:3642139|Ensembl:ENSMUSG00000025194 +100038629 Gm10463 MGI:MGI:3642170 +100038630 Gm10727 MGI:MGI:3642187 +100038631 Gm9888 MGI:MGI:3642202 +100038633 Gm10776 MGI:MGI:3642233 +100038634 Gm10657 MGI:MGI:3642259 +100038635 Arih2os MGI:MGI:3642291 +100038636 B230344G16Rik MGI:MGI:3642312 +100038637 Gm10134 MGI:MGI:3642322 +100038638 Fmr1os MGI:MGI:3642368|Ensembl:ENSMUSG00000096946 +100038639 Gm10739 MGI:MGI:3642385 +100038640 Gm10570 MGI:MGI:3642427 +100038641 Gm10452 MGI:MGI:3642443 +100038643 Gm10835 MGI:MGI:3642479 +100038644 Gm10667 MGI:MGI:3642497 +100038645 Gm10699 MGI:MGI:3642530 +100038646 Gm10576 MGI:MGI:3642535 +100038647 Gm10572 MGI:MGI:3642540 +100038648 Gm10465 MGI:MGI:3642554 +100038649 Gm10690 MGI:MGI:3642614 +100038651 D130062J21Rik MGI:MGI:3642664 +100038652 Gm10688 MGI:MGI:3642688 +100038653 Gm10538 MGI:MGI:3642693|Ensembl:ENSMUSG00000101126 +100038654 Gm10371 MGI:MGI:3642716|Ensembl:ENSMUSG00000072589 +100038656 BC048594 MGI:MGI:3041252 +100038657 7420461P10Rik MGI:MGI:3642786|Ensembl:ENSMUSG00000091060|Vega:OTTMUSG00000051918 +100038658 9830004L10Rik MGI:MGI:3642808 +100038659 Mirt2 MGI:MGI:3642813 +100038661 Gm10192 MGI:MGI:3642867 +100038662 D130046C19Rik MGI:MGI:3642886 +100038664 Gm10842 MGI:MGI:3642916 +100038666 Gm12298 MGI:MGI:3649680|Ensembl:ENSMUSG00000072834 +100038667 Macrod2os2 MGI:MGI:3651295 +100038668 Gm12526 MGI:MGI:3651778 +100038669 Plast4 MGI:MGI:3703762 +100038670 F630010C12Rik MGI:MGI:3641673 +100038671 Gm10860 MGI:MGI:3641729 +100038672 Gm10530 MGI:MGI:3641765 +100038674 Gm10764 MGI:MGI:3641850 +100038676 7120432I05Rik MGI:MGI:3641947 +100038677 Gm10588 MGI:MGI:3641952 +100038679 Gm10431 MGI:MGI:3642012 +100038680 Gm1971 MGI:MGI:3642203 +100038681 Gm10777 MGI:MGI:3642231 +100038682 Gm10475 MGI:MGI:3642283 +100038683 Gm10775 MGI:MGI:3642324 +100038684 Gm10618 MGI:MGI:3642374 +100038686 Gm10426 MGI:MGI:3642470 +100038687 Gm10577 MGI:MGI:3642534 +100038688 Gm10724 MGI:MGI:3642567 +100038689 Gm10421 MGI:MGI:3642601|Ensembl:ENSMUSG00000099907 +100038690 Gm10732 MGI:MGI:3642638 +100038691 Gm10344 MGI:MGI:3642672 +100038692 Gm10537 MGI:MGI:3642691 +100038693 Tmem51os1 MGI:MGI:3642733|Ensembl:ENSMUSG00000073728 +100038694 Gm10796 MGI:MGI:3642765 +100038695 Gm10555 MGI:MGI:3642807 +100038696 Gm10866 MGI:MGI:3642835 +100038697 Gm10912 MGI:MGI:3809094 +100038698 Gm10437 MGI:MGI:3642915 +100038699 Gm10754 MGI:MGI:3642925|Ensembl:ENSMUSG00000074776 +100038700 Gm14488 MGI:MGI:3649725 +100038701 5730424H11Rik MGI:MGI:3697819 +100038702 Gm10730 MGI:MGI:3809922 +100038703 Gm13033 MGI:MGI:3649305 +100038705 Gm10498 MGI:MGI:3641708 +100038706 Gm10637 MGI:MGI:3641741|Ensembl:ENSMUSG00000099207 +100038707 Gm10388 MGI:MGI:3641777 +100038708 Gm10855 MGI:MGI:3641819|Ensembl:ENSMUSG00000075538 +100038709 Gm10789 MGI:MGI:3641846 +100038710 Gm10748 MGI:MGI:3641901 +100038711 Gm10309 MGI:MGI:3641941 +100038712 Gm10516 MGI:MGI:3641979|Ensembl:ENSMUSG00000097316 +100038713 Gm10432 MGI:MGI:3642011|Ensembl:ENSMUSG00000113679 +100038714 Gm15401 MGI:MGI:3642201 +100038716 Gm10623 MGI:MGI:3642294 +100038717 Gm10826 MGI:MGI:3642318 +100038718 Gm10494 MGI:MGI:3642373 +100038720 Gm10425 MGI:MGI:3642471 +100038721 Gm10781 MGI:MGI:3642505 +100038722 Gm10305 MGI:MGI:3642542 +100038723 Sox5it MGI:MGI:3642586 +100038724 Gm10304 MGI:MGI:3642623 +100038725 Cep85l MGI:MGI:3642684|Ensembl:ENSMUSG00000038594 +100038726 G930009F23Rik MGI:MGI:3642701 +100038727 Gm10811 MGI:MGI:3642757 +100038728 Gm10373 MGI:MGI:3642805|Ensembl:ENSMUSG00000072592 +100038729 Gm10867 MGI:MGI:3642838 +100038730 Gm10387 MGI:MGI:3642889 +100038731 Gm10753 MGI:MGI:3642923 +100038732 Gm11681 MGI:MGI:3650778|Ensembl:ENSMUSG00000075437 +100038734 Gm10845 MGI:MGI:3641716 +100038735 Gm10384 MGI:MGI:3641812|Ensembl:ENSMUSG00000072618 +100038736 Gm10209 MGI:MGI:3641874 +100038737 Gm10403 MGI:MGI:3641963 +100038738 LOC100038738 - +100038739 Gm10615 MGI:MGI:3642102 +100038740 Gm10325 MGI:MGI:3642320 +100038741 3010085J16Rik MGI:MGI:3642414 +100038743 Gm13629 MGI:MGI:3650683 +100038746 Gm1976 MGI:MGI:3780145|Ensembl:ENSMUSG00000066057 +100038748 Gm10700 MGI:MGI:3704328 +100038750 4921514A10Rik MGI:MGI:3704238 +100038751 Gm9967 MGI:MGI:3704300 +100038752 Gm10825 MGI:MGI:3704351|Ensembl:ENSMUSG00000096937 +100038753 Gm10143 MGI:MGI:3704492 +100038755 Gm9917 MGI:MGI:3704343 +100038756 BC038268 MGI:MGI:3704403 +100038759 Gm17244 MGI:MGI:4936878 +100038761 Unc45bos MGI:MGI:3705119|Ensembl:ENSMUSG00000086058 +100038804 Itpr3os MGI:MGI:3704472 +100038806 Sicd1 MGI:MGI:3706135 +100038807 Ignpq1 MGI:MGI:3706147 +100038808 Ignpq2 MGI:MGI:3706148 +100038809 Slt3 MGI:MGI:3706328 +100038810 Mcdq1 MGI:MGI:3706141 +100038811 Ignpq3 MGI:MGI:3706149 +100038812 Slt2 MGI:MGI:3706327 +100038813 Slt4 MGI:MGI:3706329 +100038814 Slt1 MGI:MGI:3706326 +100038815 Slt5 MGI:MGI:3706330 +100038830 Gm1972 MGI:MGI:3780140 +100038833 Gm12568 MGI:MGI:3652153 +100038847 Gm10406 MGI:MGI:3711272|Ensembl:ENSMUSG00000093985|Vega:OTTMUSG00000035706 +100038850 Trav9d-3 MGI:MGI:3780142|IMGT/GENE-DB:TRAV9D-3 +100038852 Gm1974 MGI:MGI:3780143 +100038854 BC117090 MGI:MGI:3696881|Ensembl:ENSMUSG00000079594 +100038859 Olfr55 MGI:MGI:1333751|Ensembl:ENSMUSG00000094891|Vega:OTTMUSG00000059242 +100038860 Olfr239 MGI:MGI:3030073|Ensembl:ENSMUSG00000093884|Vega:OTTMUSG00000059243 +100038862 Btnl1 MGI:MGI:1932027|Ensembl:ENSMUSG00000062638|Vega:OTTMUSG00000020168 +100038875 Rps23-ps1 MGI:MGI:3705429 +100038882 Isg15 MGI:MGI:1855694|Ensembl:ENSMUSG00000035692 +100038909 Gm14548 MGI:MGI:3709645|Ensembl:ENSMUSG00000074417|Vega:OTTMUSG00000017169 +100038912 Ceacam-ps1 MGI:MGI:3610557|Ensembl:ENSMUSG00000108307 +100038914 Gm16387 MGI:MGI:3646111 +100038927 Defa30 MGI:MGI:3808881|Ensembl:ENSMUSG00000074444|Vega:OTTMUSG00000019742 +100038941 Vmn2r121 MGI:MGI:3643045|Ensembl:ENSMUSG00000072049|Vega:OTTMUSG00000018604 +100038944 Gm20791 MGI:MGI:5434147 +100038947 LOC100038947 Ensembl:ENSMUSG00000074677|Vega:OTTMUSG00000021248 +100038948 Mup9 MGI:MGI:3782918|Ensembl:ENSMUSG00000078686|Vega:OTTMUSG00000034716 +100038949 Gm1979 MGI:MGI:3780148|Ensembl:ENSMUSG00000091049|Vega:OTTMUSG00000036607 +100038953 Gm1980 MGI:MGI:3780149 +100038955 Gm1982 MGI:MGI:3780151 +100038960 Gm16431 MGI:MGI:3643167 +100038967 Gm1988 MGI:MGI:3780157 +100038968 Gm1989 MGI:MGI:3780158 +100038969 Rps12-ps18 MGI:MGI:3782928 +100038971 Gm20792 MGI:MGI:5434148 +100038972 Prss49 MGI:MGI:3780160 +100038973 Gm13835 MGI:MGI:3650921 +100038975 Gm1992 MGI:MGI:3780162 +100038976 Gm12711 MGI:MGI:3649928 +100038977 Gm1993 MGI:MGI:3780163|Ensembl:ENSMUSG00000073267|Vega:OTTMUSG00000017483 +100038978 Rps12-ps17 MGI:MGI:3643968 +100038982 Gm1995 MGI:MGI:3780165 +100038987 LOC100038987 - +100038991 Gm2000 MGI:MGI:3780170 +100038992 Gm2001 MGI:MGI:3780171|Ensembl:ENSMUSG00000113951 +100038993 Gm2002 MGI:MGI:3780172|Ensembl:ENSMUSG00000095623 +100038995 LOC100038995 Ensembl:ENSMUSG00000095523 +100038996 Gm16380 MGI:MGI:3643564 +100038997 Gm2003 MGI:MGI:3780173 +100038999 Gm13552 MGI:MGI:3650819 +100039003 Gm2005 MGI:MGI:3780175 +100039006 Gm12123 MGI:MGI:3652210 +100039008 Mup10 MGI:MGI:1924164|Ensembl:ENSMUSG00000078680|Vega:OTTMUSG00000007424 +100039010 LOC100039010 Ensembl:ENSMUSG00000095763 +100039014 Gm20793 MGI:MGI:5434149 +100039017 Gm2007 MGI:MGI:3780177 +100039019 Mup-ps12 MGI:MGI:3783148 +100039023 Gm15014 MGI:MGI:3705572 +100039026 Gm10031 MGI:MGI:3704198 +100039027 Gm2011 MGI:MGI:3780180 +100039028 Mup11 MGI:MGI:3709617|Ensembl:ENSMUSG00000073834|Vega:OTTMUSG00000007431 +100039029 LOC100039029 - +100039030 Gm2012 MGI:MGI:3780181|Ensembl:ENSMUSG00000082639|Vega:OTTMUSG00000017007 +100039032 Gm20794 MGI:MGI:5434150 +100039034 Gm20795 MGI:MGI:5434151|Ensembl:ENSMUSG00000095452|Vega:OTTMUSG00000047800 +100039036 Rps8-ps2 MGI:MGI:3649696 +100039037 Gm20796 MGI:MGI:5434152 +100039042 Gm2016 MGI:MGI:3780185|Ensembl:ENSMUSG00000072905|Vega:OTTMUSG00000042988 +100039043 Gm10731 MGI:MGI:3795712 +100039045 Gm10471 MGI:MGI:3641900|Ensembl:ENSMUSG00000073116|Vega:OTTMUSG00000036612 +100039047 Gm2018 MGI:MGI:3780187 +100039049 Gm2020 MGI:MGI:3780189 +100039050 Gm2021 MGI:MGI:3780190 +100039051 Gm11496 MGI:MGI:3649410 +100039052 Gm2022 MGI:MGI:3780191|Ensembl:ENSMUSG00000113971 +100039053 Gm2023 MGI:MGI:3780192|Ensembl:ENSMUSG00000094661 +100039054 Mup12 MGI:MGI:3780193|Ensembl:ENSMUSG00000094793|Vega:OTTMUSG00000028887 +100039055 Gm16404 MGI:MGI:3647157 +100039060 0610010B08Rik MGI:MGI:3615377|Ensembl:ENSMUSG00000078886|Vega:OTTMUSG00000016198 +100039061 Gm20797 MGI:MGI:5434153 +100039062 Gm2027 MGI:MGI:3780196 +100039063 Mup-ps8 MGI:MGI:3780197 +100039064 Rpl37a-ps3 MGI:MGI:3780198 +100039065 Gm2030 MGI:MGI:3780199|Ensembl:ENSMUSG00000083628|Vega:OTTMUSG00000017008 +100039068 Gm20798 MGI:MGI:5434154 +100039069 Gm15180 MGI:MGI:3705360 +100039072 Gm2033 MGI:MGI:3780202 +100039076 Gm2035 MGI:MGI:3780204 +100039078 Gm2036 MGI:MGI:3780205 +100039080 Gm2038 MGI:MGI:3780207 +100039083 Gm2040 MGI:MGI:3780209 +100039086 Gm15032 MGI:MGI:3705393 +100039087 Gm2042 MGI:MGI:3800544|Ensembl:ENSMUSG00000096276|Vega:OTTMUSG00000042994 +100039089 Mup13 MGI:MGI:3702003|Ensembl:ENSMUSG00000089873|Vega:OTTMUSG00000012492 +100039095 Gm2044 MGI:MGI:3780212 +100039100 Gm2046 MGI:MGI:3780214 +100039106 Gm2048 MGI:MGI:3780216 +100039109 Gm2049 MGI:MGI:3780217 +100039110 Gm12922 MGI:MGI:3651537 +100039112 Gm14938 MGI:MGI:3705415 +100039114 Gm11497 MGI:MGI:3651117 +100039116 Mup14 MGI:MGI:3702005|Ensembl:ENSMUSG00000073830|Vega:OTTMUSG00000012493 +100039120 Gm14525 MGI:MGI:3802008|Ensembl:ENSMUSG00000071788|Vega:OTTMUSG00000017011 +100039121 Gm2053 MGI:MGI:3780221 +100039123 Gm14295 MGI:MGI:3709624|Ensembl:ENSMUSG00000078877|Vega:OTTMUSG00000016219 +100039124 Vmn1r-ps2 MGI:MGI:3650274 +100039129 Gm2056 MGI:MGI:3780224 +100039133 Gm2058 MGI:MGI:3805010 +100039134 Gm2059 MGI:MGI:3780226 +100039137 Gm2060 MGI:MGI:3780227 +100039138 Gm2061 MGI:MGI:3780228|Ensembl:ENSMUSG00000097615 +100039139 Ccdc152 MGI:MGI:3641617|Ensembl:ENSMUSG00000091119 +100039141 Vmn1r-ps3 MGI:MGI:3780230 +100039142 Gm11931 MGI:MGI:3652123 +100039144 Gm38398 MGI:MGI:5618692 +100039145 Gm2066 MGI:MGI:3780233 +100039148 Gm12128 MGI:MGI:3651507|Ensembl:ENSMUSG00000087388 +100039150 Mup15 MGI:MGI:3780235|Ensembl:ENSMUSG00000096674|Vega:OTTMUSG00000028888 +100039157 Pou5f1-rs3 MGI:MGI:101890 +100039162 Gm2075 MGI:MGI:3780242 +100039163 Gm2076 MGI:MGI:3780243 +100039166 Gm14417 MGI:MGI:3652249 +100039167 Gm2077 MGI:MGI:3780244 +100039170 Gm2080 MGI:MGI:3780247 +100039174 Gm10273 MGI:MGI:3704362 +100039175 Gm9780 MGI:MGI:3710532|Ensembl:ENSMUSG00000094800|Vega:OTTMUSG00000044554 +100039176 Gm13580 MGI:MGI:3650460|Ensembl:ENSMUSG00000087283 +100039177 Mup16 MGI:MGI:3780250|Ensembl:ENSMUSG00000078675|Vega:OTTMUSG00000028884 +100039179 Gm2085 MGI:MGI:3780252 +100039182 Gm16505 MGI:MGI:3642261 +100039184 Gm13861 MGI:MGI:3649466 +100039186 Gm2087 MGI:MGI:3780254|Ensembl:ENSMUSG00000099718 +100039190 Gm2089 MGI:MGI:3780256 +100039191 Gm2090 MGI:MGI:3780257 +100039192 Tmem254c MGI:MGI:3711260|Ensembl:ENSMUSG00000072680|Vega:OTTMUSG00000044555 +100039194 Gm2092 MGI:MGI:3780259 +100039196 Gm2093 MGI:MGI:3780260 +100039198 Gm14400 MGI:MGI:3650076 +100039202 Gm2098 MGI:MGI:3780265 +100039203 Gm2099 MGI:MGI:3780266 +100039205 Gm12394 MGI:MGI:3649790 +100039206 Mup17 MGI:MGI:3705217|Ensembl:ENSMUSG00000096688|Vega:OTTMUSG00000007480 +100039208 Gm2101 MGI:MGI:3780269 +100039209 Gm20799 MGI:MGI:5434155 +100039210 Gm2102 MGI:MGI:3780270 +100039211 Gm10649 MGI:MGI:3642042|Ensembl:ENSMUSG00000074235 +100039213 Cphx2 MGI:MGI:3780272|Ensembl:ENSMUSG00000098463|Vega:OTTMUSG00000044543 +100039214 Gm16374 MGI:MGI:3648759 +100039218 Gm2106 MGI:MGI:3780274 +100039220 Gm12751 MGI:MGI:3651049 +100039221 Gm2108 MGI:MGI:3780276 +100039222 Gm2109 MGI:MGI:3780277|Ensembl:ENSMUSG00000100155 +100039225 Gm10322 MGI:MGI:3704363 +100039226 Gm16368 MGI:MGI:3647101 +100039227 Duxbl2 MGI:MGI:3710620|Ensembl:ENSMUSG00000072675|Vega:OTTMUSG00000037596 +100039229 Gm10358 MGI:MGI:3708786 +100039233 Gm14324 MGI:MGI:3652186 +100039235 Gm16529 MGI:MGI:4361268 +100039239 Gm2115 MGI:MGI:3780284 +100039240 Gm10058 MGI:MGI:3711266|Ensembl:ENSMUSG00000095293|Vega:OTTMUSG00000017020 +100039241 Gm12134 MGI:MGI:3651515 +100039242 Gm2116 MGI:MGI:3780285 +100039243 Gm15066 MGI:MGI:3706256 +100039246 Plac9b MGI:MGI:3711222|Ensembl:ENSMUSG00000072674|Vega:OTTMUSG00000044558 +100039248 Gm2117 MGI:MGI:3780287 +100039252 Gm12693 MGI:MGI:3650224 +100039254 Gm2120 MGI:MGI:3780290 +100039256 Hmgb1-ps1 MGI:MGI:3768536 +100039257 Tmem254b MGI:MGI:3710397|Ensembl:ENSMUSG00000021867|Vega:OTTMUSG00000044559 +100039258 Gm10290 MGI:MGI:3642597 +100039262 Gm2123 MGI:MGI:3780293 +100039263 Gm14428 MGI:MGI:3649514 +100039265 Gm12703 MGI:MGI:3650667 +100039269 Gm2128 MGI:MGI:3780298 +100039271 Gm20800 MGI:MGI:5434156 +100039274 Gm13555 MGI:MGI:3650412 +100039275 Rp31-ps19 MGI:MGI:3780301 +100039277 Gm14904 MGI:MGI:3705768 +100039280 Cphx3 MGI:MGI:3711264|Ensembl:ENSMUSG00000094817|Vega:OTTMUSG00000044547 +100039281 Gm10250 MGI:MGI:3642408 +100039282 Gm2136 MGI:MGI:3780305 +100039284 Gm2137 MGI:MGI:3780306 +100039285 Gm12140 MGI:MGI:3652290 +100039286 Gm2138 MGI:MGI:3780307 +100039287 Gm2139 MGI:MGI:3780308 +100039288 Gm2140 MGI:MGI:3780309 +100039289 Gm2141 MGI:MGI:3780310 +100039290 Gm2142 MGI:MGI:3780311 +100039292 Gm12142 MGI:MGI:3652294 +100039293 Duxbl3 MGI:MGI:3710520|Ensembl:ENSMUSG00000072672|Vega:OTTMUSG00000037597 +100039294 Gm20801 MGI:MGI:5434157 +100039300 Gm16373 MGI:MGI:3646158 +100039302 Gm2147 MGI:MGI:3780316 +100039303 Gm16514 MGI:MGI:4356345 +100039304 Gm2148 MGI:MGI:3780317 +100039305 Mup-ps19 MGI:MGI:3652149 +100039308 Gm2150 MGI:MGI:3780319 +100039313 Gm15060 MGI:MGI:3705758 +100039315 Gm10436 MGI:MGI:3704393|Ensembl:ENSMUSG00000066027 +100039316 Gm9843 MGI:MGI:3708621 +100039317 Gm2155 MGI:MGI:3780324 +100039319 Gm14920 MGI:MGI:3642445|Ensembl:ENSMUSG00000067441|Vega:OTTMUSG00000018481 +100039322 Gm2157 MGI:MGI:3780326 +100039324 Gm10147 MGI:MGI:3710518|Ensembl:ENSMUSG00000096457|Vega:OTTMUSG00000017033 +100039328 Gm2161 MGI:MGI:3782933 +100039331 Gm2163 MGI:MGI:3780332 +100039332 Gm2164 MGI:MGI:3780334 +100039334 Gm2165 MGI:MGI:3780335 +100039338 Gm11779 MGI:MGI:3650487 +100039340 Vmn1r-ps88 - +100039343 Gm9797 MGI:MGI:3704349 +100039344 Gm2172 MGI:MGI:3780342 +100039346 Gm2174 MGI:MGI:3780344 +100039348 Gm2176 MGI:MGI:3780346 +100039350 Gm16500 MGI:MGI:3704226 +100039353 Gm2178 MGI:MGI:3780348 +100039355 Rps16-ps2 MGI:MGI:3704259 +100039357 Gm20802 MGI:MGI:5434158 +100039359 Gm10399 MGI:MGI:3704255 +100039362 Gm2182 MGI:MGI:3780352 +100039363 Gm2183 MGI:MGI:3780353 +100039370 Gm2189 MGI:MGI:3780359 +100039374 Gm2192 MGI:MGI:3780362 +100039375 Gm15470 MGI:MGI:3641891 +100039376 Gapdh-ps14 MGI:MGI:3780363 +100039377 Gm10096 MGI:MGI:3710636|Ensembl:ENSMUSG00000095887|Vega:OTTMUSG00000017530 +100039384 Gm2199 MGI:MGI:3780369 +100039386 Gm2200 MGI:MGI:3780370 +100039389 Gm2203 MGI:MGI:3780373 +100039392 Gm12151 MGI:MGI:3649958 +100039393 Gm20803 MGI:MGI:5434159 +100039397 Gm11803 MGI:MGI:3650653 +100039405 Gm2213 MGI:MGI:3780383 +100039407 Gm2214 MGI:MGI:3780384 +100039413 Gm14294 MGI:MGI:3649965 +100039414 Gm11801 MGI:MGI:3650652 +100039417 Gm2221 MGI:MGI:3780391 +100039419 Gm2223 MGI:MGI:3780393 +100039422 Gm2225 MGI:MGI:3780395 +100039426 Gm2229 MGI:MGI:3780399 +100039429 Gm2231 MGI:MGI:3780401 +100039432 Gm2233 MGI:MGI:3780403|Ensembl:ENSMUSG00000113671 +100039436 Mageb16-ps1 MGI:MGI:3644898 +100039437 Gm11515 MGI:MGI:3649766 +100039440 B230206L02Rik MGI:MGI:1924598|Ensembl:ENSMUSG00000086003 +100039441 Gm2237 MGI:MGI:3780407|Ensembl:ENSMUSG00000093979|Vega:OTTMUSG00000036308 +100039442 Gm2238 MGI:MGI:3780408 +100039444 Gm20804 MGI:MGI:5434160 +100039446 Gm2240 MGI:MGI:3780410 +100039448 Gm12380 MGI:MGI:3651854 +100039452 Gm2244 MGI:MGI:3780414|Ensembl:ENSMUSG00000092036|Vega:OTTMUSG00000036307 +100039453 Gm2245 MGI:MGI:3780415 +100039459 Gm12691 MGI:MGI:3650220 +100039460 Gm2250 MGI:MGI:3780420 +100039462 Gm16400 MGI:MGI:3644331 +100039466 Gm2253 MGI:MGI:3780423 +100039467 Gm10487 MGI:MGI:3710592|Ensembl:ENSMUSG00000094759|Vega:OTTMUSG00000017042 +100039471 Vmn2r-ps84 MGI:MGI:3761329 +100039474 Gm15452 MGI:MGI:3768636 +100039478 Gm11810 MGI:MGI:3652275 +100039479 Vmn1r186 Ensembl:ENSMUSG00000096776 +100039484 Gm2260 MGI:MGI:3780429 +100039489 Hmgn2-ps1 MGI:MGI:3783162 +100039493 Gm2267 MGI:MGI:3780437 +100039494 Gm11799 MGI:MGI:3650446 +100039495 Gm15706 MGI:MGI:3783146|Ensembl:ENSMUSG00000086013 +100039498 Gm2270 MGI:MGI:3780440 +100039499 Vmn1r187 Ensembl:ENSMUSG00000096244 +100039501 Gm2272 MGI:MGI:3780442 +100039503 Gm2274 MGI:MGI:3780444 +100039511 Gm15110 MGI:MGI:3705883 +100039519 Gm2286 MGI:MGI:3780457 +100039521 Gm2287 MGI:MGI:3780458 +100039522 Gm2288 MGI:MGI:3780459 +100039523 Gm20805 MGI:MGI:5434161 +100039525 Rps11-ps4 MGI:MGI:3704389 +100039528 1110002E22Rik MGI:MGI:1915066 +100039532 Gm10029 MGI:MGI:3641706 +100039535 Gm2296 MGI:MGI:3780467 +100039540 Gm13602 MGI:MGI:3649285 +100039542 Tbx3os1 MGI:MGI:3780472 +100039543 Gm2302 MGI:MGI:3780473 +100039544 Gm16421 MGI:MGI:3645976 +100039545 Gm15109 MGI:MGI:3705842|Ensembl:ENSMUSG00000072929 +100039548 4930412E21Rik MGI:MGI:1924114 +100039550 Gm10486 MGI:MGI:3710516|Ensembl:ENSMUSG00000073247|Vega:OTTMUSG00000017189 +100039551 Tgif2lx2 MGI:MGI:3800824|Ensembl:ENSMUSG00000100194|Vega:OTTMUSG00000018463 +100039553 Gm2307 MGI:MGI:3780478 +100039556 Gm2308 MGI:MGI:3780479 +100039557 Gm2309 MGI:MGI:3780480 +100039560 Gm2310 MGI:MGI:3780481 +100039565 Gm11227 MGI:MGI:3651434 +100039566 Gm2314 MGI:MGI:3780485 +100039568 Gm2316 MGI:MGI:3780487 +100039571 Gm10335 MGI:MGI:3641693 +100039573 Gm2318 MGI:MGI:3780489 +100039574 Gm20806 MGI:MGI:5434162|Ensembl:ENSMUSG00000094739|Vega:OTTMUSG00000046577 +100039580 Gm2324 MGI:MGI:3780494 +100039581 Gm2325 MGI:MGI:3780495 +100039585 Gm14819 MGI:MGI:3801716|Ensembl:ENSMUSG00000073245|Vega:OTTMUSG00000018086 +100039587 Gm2328 MGI:MGI:3780498 +100039588 Gm12980 MGI:MGI:3651320 +100039589 Gm2329 MGI:MGI:3780499 +100039592 Gm10259 MGI:MGI:3704211 +100039595 Gm20807 MGI:MGI:5434163|Ensembl:ENSMUSG00000104267|Vega:OTTMUSG00000050529 +100039596 Tcf24 MGI:MGI:3780500|Ensembl:ENSMUSG00000099032|Vega:OTTMUSG00000044905 +100039600 Gm2333 MGI:MGI:3780503 +100039601 Gm10163 MGI:MGI:3704341 +100039602 Gm20808 MGI:MGI:5434164 +100039606 Gm2336 MGI:MGI:3780506 +100039608 Gm2337 MGI:MGI:3780507 +100039612 Gm15089 MGI:MGI:3705836 +100039614 Gm20809 MGI:MGI:5434165|Ensembl:ENSMUSG00000093868|Vega:OTTMUSG00000049727 +100039620 Rhox11-ps MGI:MGI:3705790 +100039621 Gm14661 MGI:MGI:3641636 +100039623 Gm15429 MGI:MGI:3642423 +100039624 Gm12166 MGI:MGI:3650635 +100039626 Gm2343 MGI:MGI:3780513 +100039628 Gm2345 MGI:MGI:3780515 +100039629 Gm2346 MGI:MGI:3780516 +100039631 Gm2347 MGI:MGI:3780517 +100039633 Gm2348 MGI:MGI:3780518 +100039634 Gm2349 MGI:MGI:3780519 +100039635 Gm2350 MGI:MGI:3826781 +100039636 Atp6v0c-ps2 MGI:MGI:2151816 +100039639 Gm11539 MGI:MGI:3651911 +100039641 E330012B07Rik MGI:MGI:3028086|Ensembl:ENSMUSG00000085600 +100039643 Gm2352 MGI:MGI:3829209 +100039645 Rpl28-ps3 MGI:MGI:3650282 +100039651 Gm15095 MGI:MGI:3705829 +100039655 Gm9745 MGI:MGI:3704398 +100039656 Gm12918 MGI:MGI:3652005 +100039659 Gm20810 MGI:MGI:5434166 +100039661 Gm2360 MGI:MGI:3780528 +100039662 Gm2361 MGI:MGI:3780529 +100039665 Gm10320 MGI:MGI:3642323 +100039668 Gm12397 MGI:MGI:3649202 +100039669 Gm15103 MGI:MGI:3705809 +100039672 Msmp MGI:MGI:3652339|Ensembl:ENSMUSG00000078719|Vega:OTTMUSG00000007017 +100039673 Gm2366 MGI:MGI:3780534 +100039674 Gm10634 MGI:MGI:3641833 +100039675 Gm20811 MGI:MGI:5434167 +100039677 Gm2367 MGI:MGI:3780535 +100039678 Gm16419 MGI:MGI:3643012 +100039681 Zcwpw2 MGI:MGI:1921888 +100039683 Gm13597 MGI:MGI:3651139 +100039684 5031434O11Rik MGI:MGI:1923230 +100039691 Lncenc1 MGI:MGI:3780541|Ensembl:ENSMUSG00000078952 +100039693 Gm20812 MGI:MGI:5434168 +100039695 Rpl19-ps1 MGI:MGI:3642668 +100039700 Gm16423 MGI:MGI:3644740 +100039704 Gm2379 MGI:MGI:3780547 +100039706 Gm2381 MGI:MGI:3780549|Ensembl:ENSMUSG00000092225|Vega:OTTMUSG00000037912 +100039707 Mthfsl MGI:MGI:3780550|Ensembl:ENSMUSG00000079427|Vega:OTTMUSG00000045603 +100039709 Gm2383 MGI:MGI:3780551 +100039715 Gm14550 MGI:MGI:3705668 +100039716 Gm15131 MGI:MGI:3642416 +100039720 Gm2387 MGI:MGI:3780555 +100039723 Gm2389 MGI:MGI:3780557 +100039724 Fkbp1a-ps3 MGI:MGI:3641946 +100039725 Gm2390 MGI:MGI:3780558 +100039726 Gm11486 MGI:MGI:3650706 +100039727 1700049E15Rik MGI:MGI:1920644|Ensembl:ENSMUSG00000085077 +100039730 Gm12168 MGI:MGI:3650839 +100039731 Gm10051 MGI:MGI:3641791|Ensembl:ENSMUSG00000058905 +100039732 Gm20813 MGI:MGI:5434169 +100039733 Gm2393 MGI:MGI:3780561 +100039735 Gm2395 MGI:MGI:3780563 +100039736 Gm15762 MGI:MGI:3783204 +100039739 A430060F13Rik MGI:MGI:3026970 +100039740 Gm10260 MGI:MGI:3642298 +100039741 Gm2396 MGI:MGI:3780564 +100039743 Gm2398 MGI:MGI:3780566 +100039744 Gm2399 MGI:MGI:3780567 +100039746 Gm2401 MGI:MGI:3780569 +100039748 Gm10020 MGI:MGI:3642192 +100039750 Gm2404 MGI:MGI:3780572 +100039751 Rps12-ps21 MGI:MGI:3648701 +100039752 Gm20814 MGI:MGI:5434170 +100039753 Gm20815 MGI:MGI:5434171|Ensembl:ENSMUSG00000101053|Vega:OTTMUSG00000046144 +100039756 Gm2407 MGI:MGI:3780575 +100039757 Gm10153 MGI:MGI:3642359 +100039760 Gm15148 MGI:MGI:3705350 +100039762 Gm10293 MGI:MGI:3704216 +100039763 Gm2411 MGI:MGI:3809203 +100039764 Gm2412 MGI:MGI:3780579 +100039766 Gm16510 MGI:MGI:3642319 +100039768 1700024F20Rik MGI:MGI:1919101 +100039774 Gm11405 MGI:MGI:3651226 +100039775 Gm2420 MGI:MGI:3780587 +100039778 Gm14666 MGI:MGI:3705418 +100039781 Hrct1 MGI:MGI:1917945|Ensembl:ENSMUSG00000071001|Vega:OTTMUSG00000007082 +100039782 Gm10709 MGI:MGI:3642754 +100039786 Gm2423 MGI:MGI:3805957 +100039787 Gm2424 MGI:MGI:3780590 +100039789 Gm12407 MGI:MGI:3693096 +100039790 Trbv3 MGI:MGI:98590|IMGT/GENE-DB:TRBV3 +100039794 Gm2427 MGI:MGI:3780593 +100039795 Ildr2 MGI:MGI:1196370|Ensembl:ENSMUSG00000040612|Vega:OTTMUSG00000021748 +100039796 Tgtp2 MGI:MGI:3710083|Ensembl:ENSMUSG00000078921|Vega:OTTMUSG00000005537 +100039798 Gm2429 MGI:MGI:3780596 +100039799 Gm12962 MGI:MGI:3650901 +100039800 Gm2431 MGI:MGI:3780598 +100039801 Cldn24 MGI:MGI:3712484|Ensembl:ENSMUSG00000061974|Vega:OTTMUSG00000061829 +100039802 Gm14614 MGI:MGI:3705705 +100039805 D5Ertd605e MGI:MGI:1277165|Ensembl:ENSMUSG00000106820 +100039810 Gm20816 MGI:MGI:5434172|Ensembl:ENSMUSG00000095634|Vega:OTTMUSG00000045925 +100039814 Gm11258 MGI:MGI:3649983 +100039815 Gm2436 MGI:MGI:3780603 +100039818 Gm2439 MGI:MGI:3780606 +100039820 Gm16020 MGI:MGI:3801865 +100039827 Gm2445 MGI:MGI:3780612 +100039828 Rps12-ps6 MGI:MGI:3643035 +100039830 Gm2446 MGI:MGI:3780613 +100039833 Gm11259 MGI:MGI:3649975 +100039834 Gm12790 MGI:MGI:3649398 +100039835 Gm13214 MGI:MGI:3650812 +100039837 Gm2449 MGI:MGI:3780616 +100039840 Gm2451 MGI:MGI:3780618 +100039842 Gm20817 MGI:MGI:5434173 +100039843 Gm2452 MGI:MGI:3780619 +100039844 Gm2453 MGI:MGI:3780620 +100039848 Gm2457 MGI:MGI:3780624 +100039850 Gm2458 MGI:MGI:3780625 +100039855 Gm2461 MGI:MGI:3780628 +100039861 Gm2464 MGI:MGI:3780631 +100039862 Gm11833 MGI:MGI:3650311 +100039863 Gm13306 MGI:MGI:3713752|Ensembl:ENSMUSG00000073877|Vega:OTTMUSG00000011352 +100039864 Snhg12 MGI:MGI:1916721|Ensembl:ENSMUSG00000086290 +100039865 LOC100039865 - +100039870 Gm2467 MGI:MGI:3780634 +100039871 Gm2468 MGI:MGI:3780635 +100039875 Gm10313 MGI:MGI:3642852 +100039876 Gm20818 MGI:MGI:5434174 +100039882 Gm2474 MGI:MGI:3780641 +100039884 Gm11256 MGI:MGI:3650655 +100039885 Vmn1r-ps5 MGI:MGI:3780643 +100039888 Gm11223 MGI:MGI:3651631 +100039889 1700047F07Rik MGI:MGI:1920570 +100039890 Gm15093 MGI:MGI:3712496|Ensembl:ENSMUSG00000094941|Vega:OTTMUSG00000018984 +100039893 Gm2477 MGI:MGI:3780644 +100039895 Gm2479 MGI:MGI:3780646 +100039896 Vmn1r-ps6 MGI:MGI:3780647 +100039899 Tex13d MGI:MGI:3780650|Ensembl:ENSMUSG00000105993|Vega:OTTMUSG00000054810 +100039901 2810407A14Rik MGI:MGI:1917461 +100039904 Gm20819 MGI:MGI:5434175 +100039905 Gm20820 MGI:MGI:5434176|Ensembl:ENSMUSG00000100240|Vega:OTTMUSG00000047031 +100039911 Gm2491 MGI:MGI:3780658 +100039913 Rhox2b MGI:MGI:3770262|Ensembl:ENSMUSG00000079638|Vega:OTTMUSG00000017138 +100039914 Gm20821 MGI:MGI:5434177 +100039916 Gm2492 MGI:MGI:3780659 +100039917 Gm13022 MGI:MGI:3651775 +100039921 Gm2495 MGI:MGI:3780662 +100039924 Rps13-ps2 MGI:MGI:3704295 +100039925 Gm2497 MGI:MGI:3780664 +100039934 Gm15085 MGI:MGI:3712210|Ensembl:ENSMUSG00000095621|Vega:OTTMUSG00000018973 +100039938 Gm2505 MGI:MGI:3780672 +100039939 Gm2506 MGI:MGI:3780673|Ensembl:ENSMUSG00000093828 +100039940 Gm12715 MGI:MGI:3650759 +100039945 Gm12184 MGI:MGI:3652174 +100039946 Gm2511 MGI:MGI:3780678|Ensembl:ENSMUSG00000108695 +100039948 Rhox2c MGI:MGI:3770266|Ensembl:ENSMUSG00000079637|Vega:OTTMUSG00000017149 +100039953 Gfy MGI:MGI:2685427|Ensembl:ENSMUSG00000095276|Vega:OTTMUSG00000058650 +100039954 Gm2516 MGI:MGI:3780683|Ensembl:ENSMUSG00000110281 +100039955 Gm2517 MGI:MGI:3780684 +100039957 Gm2518 MGI:MGI:3780685 +100039958 Gm11843 MGI:MGI:3651166 +100039959 Gm10566 MGI:MGI:3642220 +100039964 Gm15411 MGI:MGI:3705213 +100039965 Gm2522 MGI:MGI:3780689 +100039968 Tmem35b MGI:MGI:3758095|Ensembl:ENSMUSG00000070737|Vega:OTTMUSG00000009332 +100039973 Gm13309 MGI:MGI:3702000 +100039978 Gm2531 MGI:MGI:3780699 +100039979 Rps18-ps1 MGI:MGI:3650249 +100039983 Gm2534 MGI:MGI:3780702 +100039987 Gm14580 MGI:MGI:3705578 +100039988 Gm11826 MGI:MGI:3651142 +100039992 Gm2539 MGI:MGI:3780707 +100039994 Gm2541 MGI:MGI:3780709 +100039996 Gm11260 MGI:MGI:3651928 +100039999 Gm2544 MGI:MGI:3780712 +100040000 Gm2545 MGI:MGI:3780713 +100040001 Gm2546 MGI:MGI:3780714 +100040007 Gm2551 MGI:MGI:3780719 +100040009 Gm2553 MGI:MGI:3780721 +100040011 Gm14673 MGI:MGI:3705555 +100040014 Gm11527 MGI:MGI:3649799 +100040016 Rhox2e MGI:MGI:3770272|Ensembl:ENSMUSG00000096788|Vega:OTTMUSG00000017141 +100040018 Gmfg-ps MGI:MGI:3704264 +100040020 Gm15143 MGI:MGI:3705874 +100040021 Rpl9-ps7 MGI:MGI:3642824 +100040022 Gm20822 MGI:MGI:5434178|Ensembl:ENSMUSG00000095172|Vega:OTTMUSG00000049720 +100040027 Gm2559 MGI:MGI:3780727 +100040029 Gm10232 MGI:MGI:3641637 +100040030 Gm2560 MGI:MGI:3780728 +100040031 Gm20823 MGI:MGI:5434179|Ensembl:ENSMUSG00000093950|Vega:OTTMUSG00000045558 +100040035 Gm2564 MGI:MGI:3708691 +100040037 Gm2566 MGI:MGI:3780733 +100040038 Gm14606 MGI:MGI:3705612 +100040044 Gm2568 MGI:MGI:3780735 +100040048 Ccl27b MGI:MGI:1891389|Ensembl:ENSMUSG00000096826 +100040049 1810010D01Rik MGI:MGI:1916283|Ensembl:ENSMUSG00000109305|Vega:OTTMUSG00000059416 +100040052 Gm2573 MGI:MGI:3780740 +100040053 Gm2574 MGI:MGI:3780741 +100040054 Gm20824 MGI:MGI:5434180 +100040067 Gm2582 MGI:MGI:3780750 +100040073 Gm12193 MGI:MGI:3651287 +100040076 Gm15141 MGI:MGI:3705823 +100040083 Gm20825 MGI:MGI:5434181 +100040086 Gm2590 MGI:MGI:3780758 +100040090 Gm2594 MGI:MGI:3780762 +100040092 Gm14984 MGI:MGI:3705580 +100040095 Gm11858 MGI:MGI:3649986 +100040099 Gm10784 MGI:MGI:3642059 +100040105 Gm2602 MGI:MGI:3780770 +100040109 Gm2606 MGI:MGI:3780774 +100040110 Gm12739 MGI:MGI:3651018 +100040112 LOC100040112 - +100040113 Gm2607 MGI:MGI:3780775 +100040119 Gm2611 MGI:MGI:3780779 +100040123 Gm2614 MGI:MGI:3780782 +100040129 Gm10270 MGI:MGI:3642297 +100040130 Gm2617 MGI:MGI:3780785 +100040131 Gm11765 MGI:MGI:3651002 +100040133 Gm14608 MGI:MGI:3705697 +100040135 Gm2619 MGI:MGI:3780787 +100040139 Gm2622 MGI:MGI:3780790 +100040140 Gm12411 MGI:MGI:3649918 +100040141 Gm2623 MGI:MGI:3780791 +100040144 Gm11412 MGI:MGI:3650905 +100040150 Gm2628 MGI:MGI:3780796 +100040151 Gm2629 MGI:MGI:3780797 +100040158 Gm2635 MGI:MGI:3780803 +100040160 Gm20826 MGI:MGI:5434182|Ensembl:ENSMUSG00000094081|Vega:OTTMUSG00000045879 +100040162 Gm2638 MGI:MGI:3780806 +100040163 Gm2639 MGI:MGI:3780807 +100040165 Gm2641 MGI:MGI:3780809 +100040169 Rpl35a-ps5 MGI:MGI:3704247 +100040171 Gm20827 MGI:MGI:5434183 +100040172 Gm13667 MGI:MGI:3650879 +100040173 Gm11849 MGI:MGI:3652012 +100040176 Gm2645 MGI:MGI:3780813 +100040177 Gm13642 MGI:MGI:3651865 +100040182 Rpl30-ps7 MGI:MGI:3780816 +100040183 Gm2649 MGI:MGI:3780817 +100040185 Gm2651 MGI:MGI:3780819 +100040187 Gm20828 MGI:MGI:5434184|Ensembl:ENSMUSG00000094838|Vega:OTTMUSG00000046775 +100040190 Gm2654 MGI:MGI:3780822 +100040191 Krtap19-9a MGI:MGI:3704466 +100040194 Gm14688 MGI:MGI:3705448 +100040196 Gm20830 MGI:MGI:5434186 +100040200 Gm12358 MGI:MGI:3649955 +100040201 Gm10229 MGI:MGI:3711943|Ensembl:ENSMUSG00000068075 +100040203 Scgb2a2 MGI:MGI:3780828 +100040208 Gm2663 MGI:MGI:3780832|Ensembl:ENSMUSG00000096525|Vega:OTTMUSG00000051312 +100040209 H2af-ps MGI:MGI:3783096 +100040211 Rsf1os2 MGI:MGI:3642179 +100040213 Gm2666 MGI:MGI:3780835 +100040214 Gm10228 MGI:MGI:3704467|Ensembl:ENSMUSG00000068074 +100040218 Gm2670 MGI:MGI:3780839 +100040219 Gm13182 MGI:MGI:3650465 +100040220 Gm9892 MGI:MGI:3701610 +100040221 Gm15149 MGI:MGI:3705399 +100040223 Gm20831 MGI:MGI:5434187|Ensembl:ENSMUSG00000094325|Vega:OTTMUSG00000045357 +100040225 Gm20832 MGI:MGI:5434188 +100040227 Gm2672 MGI:MGI:3780841 +100040228 Gm2673 MGI:MGI:3780842 +100040229 Gm15353 MGI:MGI:3705219 +100040231 Gm2675 MGI:MGI:3780844 +100040232 Gm9791 MGI:MGI:3642317 +100040233 Gm10334 MGI:MGI:3641889|Ensembl:ENSMUSG00000071517|Vega:OTTMUSG00000051423 +100040234 Gm2676 MGI:MGI:3780845 +100040239 Gm15173 MGI:MGI:3642212 +100040242 Gm11531 MGI:MGI:3650260 +100040244 Gm14698 MGI:MGI:3709613 +100040248 Gm11563 MGI:MGI:3650330|Ensembl:ENSMUSG00000069718|Vega:OTTMUSG00000002200 +100040249 Krtap6-3 MGI:MGI:1330279 +100040250 Gm13193 MGI:MGI:3651271 +100040252 Gm12742 MGI:MGI:3651646 +100040253 Gm2679 MGI:MGI:3780848 +100040255 Gm14700 MGI:MGI:3705678 +100040257 Gm13180 MGI:MGI:3650463 +100040259 Mif-ps6 MGI:MGI:103158 +100040260 Atf1-ps MGI:MGI:3037720 +100040262 Gm20833 MGI:MGI:5434189 +100040263 Gm20834 MGI:MGI:5434190 +100040264 Gm20835 MGI:MGI:5434191 +100040266 Gm2682 MGI:MGI:3780851 +100040268 Olfr157 MGI:MGI:1352684|Ensembl:ENSMUSG00000111611|Vega:OTTMUSG00000007131 +100040270 Rapgef4os1 MGI:MGI:3649714 +100040271 Gm15482 MGI:MGI:3705142 +100040276 Gm11595 MGI:MGI:3652308|Ensembl:ENSMUSG00000078668|Vega:OTTMUSG00000002543 +100040281 Gm10061 MGI:MGI:3642175 +100040285 Gm2691 MGI:MGI:3780860 +100040287 Gm16418 MGI:MGI:3644548 +100040291 Gm2693 MGI:MGI:3780862 +100040292 Gm13197 MGI:MGI:3652146 +100040293 Mindy4b-ps MGI:MGI:2140018|Ensembl:ENSMUSG00000101860 +100040294 Gm2694 MGI:MGI:3780864|Ensembl:ENSMUSG00000097248 +100040295 Gm15035 MGI:MGI:3705594 +100040297 Gm2695 MGI:MGI:3780865 +100040298 Gm15501 MGI:MGI:3704296 +100040299 Gm2696 MGI:MGI:3780866|Ensembl:ENSMUSG00000112600 +100040303 Gm2700 MGI:MGI:3780870 +100040304 Gm16407 MGI:MGI:3644720 +100040305 Gm2701 MGI:MGI:3780871 +100040307 Gm2703 MGI:MGI:3826683 +100040313 Gm12503 MGI:MGI:3651570 +100040314 Gm2707 MGI:MGI:3780876 +100040317 Gm14598 MGI:MGI:3807565 +100040319 Gm2709 MGI:MGI:3780878 +100040320 Gm2710 MGI:MGI:3780879 +100040322 3830408C21Rik MGI:MGI:1917940 +100040326 Gm12741 MGI:MGI:3651642 +100040328 Gm2716 MGI:MGI:3780885 +100040331 Rpl36a-ps2 MGI:MGI:3780887 +100040333 Gm2719 MGI:MGI:3780888 +100040335 Gm20836 MGI:MGI:5434192 +100040339 Gm2721 MGI:MGI:3780890|Ensembl:ENSMUSG00000113314 +100040340 Gm11273 MGI:MGI:3649411 +100040342 Gm10231 MGI:MGI:3704468 +100040344 Gm15033 MGI:MGI:3705364 +100040350 Gm2726 MGI:MGI:3780895 +100040353 2810416G20Rik MGI:MGI:1914374 +100040357 Gm20837 MGI:MGI:5434193 +100040360 Gm2734 MGI:MGI:3780903 +100040361 Gm2735 MGI:MGI:3780904 +100040363 Gm20838 MGI:MGI:5434194 +100040366 Gm2736 MGI:MGI:3780905 +100040371 Gm15189 MGI:MGI:3705441 +100040373 Gm11523 MGI:MGI:3651808 +100040387 Gm13391 MGI:MGI:3651526 +100040388 Gm12551 MGI:MGI:3651664 +100040394 Gm15267 MGI:MGI:3705447 +100040400 Gm20840 MGI:MGI:5434196 +100040403 Gm2754 MGI:MGI:3780923 +100040407 Gm2756 MGI:MGI:3780925 +100040409 Gm14724 MGI:MGI:3705618 +100040410 Gm14957 MGI:MGI:3705824 +100040413 Gm10075 MGI:MGI:3710521 +100040414 Rpl30-ps6 MGI:MGI:3642608 +100040416 Rpl13-ps6 MGI:MGI:3642685|Ensembl:ENSMUSG00000059776 +100040417 Gm2759 MGI:MGI:3780928 +100040418 Gm20841 MGI:MGI:5434197 +100040421 Gm2762 MGI:MGI:3780931|Ensembl:ENSMUSG00000107008 +100040426 Gm13192 MGI:MGI:3651075 +100040429 Gm20842 MGI:MGI:5434198 +100040431 Gm2767 MGI:MGI:3780936 +100040432 Gm14732 MGI:MGI:3705672 +100040433 Gm2768 MGI:MGI:3780937 +100040437 Gm2769 MGI:MGI:3780938 +100040439 Eif1-ps1 MGI:MGI:3642383 +100040442 Gm2773 MGI:MGI:3780942 +100040443 Gm2774 MGI:MGI:3780943 +100040447 1700036A12Rik MGI:MGI:1920548 +100040448 Btbd35f19 MGI:MGI:3780946|Ensembl:ENSMUSG00000094352 +100040453 Ppp1r2-ps1 MGI:MGI:3809199 +100040454 Gm10212 MGI:MGI:3641904 +100040458 Btbd35f26 MGI:MGI:3780952|Ensembl:ENSMUSG00000095229 +100040462 Mndal MGI:MGI:3780953|Ensembl:ENSMUSG00000090272|Vega:OTTMUSG00000045572 +100040465 Gm2788 MGI:MGI:3780956 +100040467 Spin2f MGI:MGI:3780958 +100040470 Gm2791 MGI:MGI:3780959 +100040471 Gm2792 MGI:MGI:3780960 +100040475 Gm2795 MGI:MGI:3780964 +100040476 Gm14464 MGI:MGI:3651392 +100040478 Gm2796 MGI:MGI:3780965 +100040482 Btbd35f2 MGI:MGI:3780968|Ensembl:ENSMUSG00000096194 +100040483 Gm20843 MGI:MGI:5434199 +100040484 Gm2800 MGI:MGI:3780969 +100040488 Ppp1r2-ps5 MGI:MGI:3780971 +100040489 Gm20844 MGI:MGI:5434200 +100040491 Gm12349 MGI:MGI:3650494 +100040492 Gm2803 MGI:MGI:3780972 +100040493 Gm13429 MGI:MGI:3651652 +100040496 Gm2805 MGI:MGI:3780974 +100040500 Gm2808 MGI:MGI:3780977 +100040502 Gm2810 MGI:MGI:3780980 +100040505 Gm9923 MGI:MGI:3704365 +100040507 Gm2814 MGI:MGI:3780984 +100040508 Gm2815 MGI:MGI:3780985 +100040509 Gm20845 MGI:MGI:5434201 +100040514 Defa-ps14 MGI:MGI:3705817 +100040519 Mrpl23-ps1 MGI:MGI:3650679 +100040524 Gm2822 MGI:MGI:3780992 +100040525 Tmem181c-ps MGI:MGI:3780993 +100040526 Gm14465 MGI:MGI:3651393 +100040528 Defa-ps15 MGI:MGI:3705808 +100040529 Gm2824 MGI:MGI:3780995 +100040531 Dynlt1f MGI:MGI:3780996|Ensembl:ENSMUSG00000095677 +100040532 Gm12967 MGI:MGI:3652042 +100040533 Btbd35f5 MGI:MGI:3780997|Ensembl:ENSMUSG00000094727 +100040537 Gm2828 MGI:MGI:3781000 +100040538 Gm10448 MGI:MGI:3642115 +100040540 Gm10288 MGI:MGI:3704227 +100040542 Gm2829 MGI:MGI:3781001 +100040543 Gm2830 MGI:MGI:3781002 +100040545 Gm2832 MGI:MGI:3781004 +100040550 Gm2836 MGI:MGI:3781008 +100040551 Gm10036 MGI:MGI:3642334 +100040552 Gm2837 MGI:MGI:3781009 +100040557 Gm12408 MGI:MGI:3649921|Ensembl:ENSMUSG00000085980 +100040558 BE691133 MGI:MGI:3035105 +100040559 Gm2840 MGI:MGI:3781012 +100040561 Gm15359 MGI:MGI:3705375 +100040563 Dynlt1c MGI:MGI:3807476|Ensembl:ENSMUSG00000000579|Vega:OTTMUSG00000023344 +100040564 Gm20846 MGI:MGI:5434202 +100040567 Gm12409 MGI:MGI:3649923|Ensembl:ENSMUSG00000085876 +100040568 Gm2845 MGI:MGI:3781017 +100040572 Gm2848 MGI:MGI:3781020 +100040580 Gm12412 MGI:MGI:3649919 +100040581 Gm12817 MGI:MGI:3649633 +100040585 Gm2854 MGI:MGI:3781026|Ensembl:ENSMUSG00000095264 +100040587 Gm2855 MGI:MGI:3781029 +100040589 Gm10242 MGI:MGI:3642310 +100040591 Kcnj13 MGI:MGI:3781032|Ensembl:ENSMUSG00000079436|Vega:OTTMUSG00000037066 +100040595 Gm20847 MGI:MGI:5434203 +100040597 Gm2860 MGI:MGI:3781036 +100040598 Gm2861 MGI:MGI:3781037 +100040599 Gm15319 MGI:MGI:3796981|Ensembl:ENSMUSG00000074449|Vega:OTTMUSG00000020118 +100040602 Gm2862 MGI:MGI:3781038 +100040605 Gm15710 MGI:MGI:3783151 +100040606 Btbd35f12 MGI:MGI:3781040|Ensembl:ENSMUSG00000101500|Vega:OTTMUSG00000019719 +100040607 Gm12813 MGI:MGI:3650999 +100040608 Fancf MGI:MGI:3689889|Ensembl:ENSMUSG00000092118|Vega:OTTMUSG00000059027 +100040609 Gm14584 MGI:MGI:3705780 +100040610 Gm15212 MGI:MGI:3705744 +100040611 Gm10154 MGI:MGI:3642271 +100040612 Spin2-ps6 MGI:MGI:3781041 +100040615 Gm2866 MGI:MGI:3781043 +100040617 Gm12603 MGI:MGI:3649757|Ensembl:ENSMUSG00000085183 +100040619 Gm2869 MGI:MGI:3781046 +100040621 Gm2871 MGI:MGI:3781048 +100040624 Gm13756 MGI:MGI:3651887 +100040628 Gm2875 MGI:MGI:3781052 +100040632 AA684185 MGI:MGI:3034637 +100040633 Rpsa-ps10 MGI:MGI:3704228 +100040634 Gm10284 MGI:MGI:3704311 +100040635 Gm15023 MGI:MGI:3805552|Ensembl:ENSMUSG00000079432|Vega:OTTMUSG00000018782 +100040636 Gm20848 MGI:MGI:5434204 +100040639 Vmn1r-ps128 MGI:MGI:3651039 +100040640 Gm15285 MGI:MGI:3705624 +100040641 Gm2877 MGI:MGI:3781055 +100040642 Gm2878 MGI:MGI:3781056 +100040643 Gm12443 MGI:MGI:3651437 +100040644 Gm14592 MGI:MGI:3705794 +100040648 Gm13390 MGI:MGI:3705123 +100040654 Gm2885 MGI:MGI:3781063 +100040657 Gm2888 MGI:MGI:3781066|Ensembl:ENSMUSG00000090487 +100040658 Gm2889 MGI:MGI:3781067 +100040661 Gm9825 MGI:MGI:3708729 +100040662 Gm2892 MGI:MGI:3781070 +100040667 Gm2895 MGI:MGI:3781073 +100040668 Defa-ps16 MGI:MGI:3705774 +100040671 Gm2897 MGI:MGI:3781075|Ensembl:ENSMUSG00000079410|Vega:OTTMUSG00000035982 +100040678 Gm15309 MGI:MGI:3705458 +100040681 Hspe1-ps1 MGI:MGI:1935161 +100040682 Gm2904 MGI:MGI:3781082 +100040687 Gm11584 MGI:MGI:3651394 +100040688 Gm2907 MGI:MGI:3781085 +100040690 Gm13263 MGI:MGI:3650829 +100040691 Gm11914 MGI:MGI:3649889 +100040693 Defa-ps17 MGI:MGI:3705788 +100040695 Vmn2r-ps143 MGI:MGI:3761705 +100040696 Gm2912 MGI:MGI:3781090 +100040697 Gm10340 MGI:MGI:3641969 +100040698 Btbd35f15 MGI:MGI:3781091|Ensembl:ENSMUSG00000101294|Vega:OTTMUSG00000019716 +100040699 Gm2914 MGI:MGI:3781092 +100040700 Gm2915 MGI:MGI:3781093 +100040701 Gm2916 MGI:MGI:3781094 +100040703 Gm13297 MGI:MGI:3649442 +100040706 Gm15312 MGI:MGI:3705692 +100040707 Gm2920 MGI:MGI:3781098 +100040708 Atp5l2-ps MGI:MGI:3649364 +100040710 Gm13219 MGI:MGI:3651678|Ensembl:ENSMUSG00000079604 +100040711 Gm2921 MGI:MGI:3781099 +100040712 Gm20850 MGI:MGI:5434206|Ensembl:ENSMUSG00000100902|Vega:OTTMUSG00000046435 +100040714 Gm20851 MGI:MGI:5434207 +100040719 Gm14599 MGI:MGI:3705841 +100040721 Gm2926 MGI:MGI:3781104 +100040722 Btbd35f13 MGI:MGI:3781105|Ensembl:ENSMUSG00000095934|Vega:OTTMUSG00000019726 +100040724 Mirg MGI:MGI:3781106|Ensembl:ENSMUSG00000097391 +100040726 Gm2930 MGI:MGI:3781108 +100040728 Gm13017 MGI:MGI:3650528 +100040729 Defa-ps10 MGI:MGI:3705783 +100040732 Btbd35f14 MGI:MGI:3781111|Ensembl:ENSMUSG00000078324 +100040733 Gm13295 MGI:MGI:3649471 +100040736 Foxd2os MGI:MGI:2444065|Ensembl:ENSMUSG00000085399 +100040739 Defa-ps11 MGI:MGI:3705879 +100040741 Gm2939 MGI:MGI:3781117 +100040744 Gm21394 MGI:MGI:5434749 +100040745 Rpl17-ps3 MGI:MGI:3642206 +100040752 Gm2947 MGI:MGI:3781125 +100040757 Gm2950 MGI:MGI:3781128 +100040759 Gm2951 MGI:MGI:3781129 +100040766 Mroh2a MGI:MGI:3705228|Ensembl:ENSMUSG00000079429|Vega:OTTMUSG00000020804 +100040769 Gm15506 MGI:MGI:3782954 +100040771 Gm2959 MGI:MGI:3781137 +100040773 Gm11910 MGI:MGI:3651484 +100040775 Gm2961 MGI:MGI:3781139 +100040781 Btbd35f6 MGI:MGI:3781142|Ensembl:ENSMUSG00000096915 +100040785 Gm2965 MGI:MGI:3781143 +100040786 Gm20852 MGI:MGI:5434208|Ensembl:ENSMUSG00000096666|Vega:OTTMUSG00000045859 +100040787 Gm2966 MGI:MGI:3781144 +100040789 Gm16428 MGI:MGI:3648457 +100040792 Gm11627 MGI:MGI:3650659|Ensembl:ENSMUSG00000078640|Vega:OTTMUSG00000002879 +100040794 Gm2970 MGI:MGI:3781148 +100040795 Gm15223 MGI:MGI:3705339 +100040801 Gm2974 MGI:MGI:3781152 +100040804 Gm2975 MGI:MGI:3781153 +100040805 Gm2976 MGI:MGI:3781154 +100040807 Gm2977 MGI:MGI:3781155 +100040809 Gm2979 MGI:MGI:3781157 +100040811 Gm11919 MGI:MGI:3650122 +100040812 Gm2981 MGI:MGI:3781159 +100040814 Amd-ps4 MGI:MGI:3650439 +100040818 Gm13682 MGI:MGI:3652287 +100040820 Gm2984 MGI:MGI:3781162 +100040822 Gm1604a MGI:MGI:3807545 +100040823 Gm10269 MGI:MGI:3642381 +100040826 Gm2986 MGI:MGI:3781164 +100040834 Gm2990 MGI:MGI:3781168 +100040835 Gm2991 MGI:MGI:3781169 +100040839 Gm2995 MGI:MGI:3781173 +100040840 Gm2996 MGI:MGI:3781174 +100040843 Cyp4a32 MGI:MGI:3717148|Ensembl:ENSMUSG00000063929|Vega:OTTMUSG00000008689 +100040846 5930403N24Rik MGI:MGI:2444171 +100040851 Gm9767 MGI:MGI:3704352|Ensembl:ENSMUSG00000039098 +100040852 Gm3002 MGI:MGI:3781180 +100040853 Gm9845 MGI:MGI:3704215 +100040854 Gm13040 MGI:MGI:3649498|Ensembl:ENSMUSG00000070616|Vega:OTTMUSG00000010130 +100040857 Gm3004 MGI:MGI:3781182 +100040861 Gm13057 MGI:MGI:3649690|Ensembl:ENSMUSG00000096154|Vega:OTTMUSG00000010207 +100040863 Gm3008 MGI:MGI:3781186 +100040865 Gm3010 MGI:MGI:3781188 +100040866 Gm3011 MGI:MGI:3781189 +100040867 Gm16405 MGI:MGI:3647662|Ensembl:ENSMUSG00000096468|Vega:OTTMUSG00000017376 +100040870 Gm3005 MGI:MGI:3781183 +100040872 Gm3014 MGI:MGI:3781192 +100040873 Gm20853 MGI:MGI:5434209 +100040875 Gm3015 MGI:MGI:3781193 +100040877 Gm3017 MGI:MGI:3781195 +100040880 Gm3020 MGI:MGI:3781198 +100040882 1700017G19Rik MGI:MGI:1919477|Ensembl:ENSMUSG00000037884 +100040883 Vma21-ps MGI:MGI:3643145 +100040885 Gm16427 MGI:MGI:3704103|Ensembl:ENSMUSG00000096044|Vega:OTTMUSG00000055692 +100040890 Gm3025 MGI:MGI:3781203 +100040892 Gm3027 MGI:MGI:3781205 +100040893 Gm3028 MGI:MGI:3781206 +100040894 Gm16430 MGI:MGI:3643726|Ensembl:ENSMUSG00000094714|Vega:OTTMUSG00000017372 +100040897 Gm3029 MGI:MGI:3781207 +100040898 Gm13292 MGI:MGI:3649470 +100040899 Gm15142 MGI:MGI:3705871 +100040900 Gm3030 MGI:MGI:3781208 +100040902 Gm3032 MGI:MGI:3781210 +100040906 Gm3033 MGI:MGI:3781211 +100040911 Gm20854 MGI:MGI:5434210|Ensembl:ENSMUSG00000095650|Vega:OTTMUSG00000042966 +100040914 Gm10518 MGI:MGI:3704205 +100040923 Gm3043 MGI:MGI:3781221|Ensembl:ENSMUSG00000090364|Vega:OTTMUSG00000036297 +100040924 Gm13082 MGI:MGI:3650233 +100040926 Gm3045 MGI:MGI:3781223|Ensembl:ENSMUSG00000110477|Vega:OTTMUSG00000061816 +100040928 Gm3047 MGI:MGI:3781225 +100040929 Gm10362 MGI:MGI:3642619 +100040933 Gm16397 MGI:MGI:3648067 +100040935 Gm3050 MGI:MGI:3781228 +100040937 Cldn34b1 MGI:MGI:3648403|Ensembl:ENSMUSG00000072100|Vega:OTTMUSG00000019269 +100040938 Gm3052 MGI:MGI:3781230 +100040939 Gm11354 MGI:MGI:3650603 +100040940 Gm3053 MGI:MGI:3781231 +100040941 Gm3054 MGI:MGI:3781232 +100040944 Gm3055 MGI:MGI:3809197 +100040950 Gm15246 MGI:MGI:3708120 +100040951 Vmn2r-ps141 MGI:MGI:3761698 +100040957 Gm11355 MGI:MGI:3649791 +100040961 Gm10145 MGI:MGI:3704353 +100040962 Gm3065 MGI:MGI:3781242 +100040963 Gm20855 MGI:MGI:5434211 +100040970 Rpl14-ps1 MGI:MGI:3710579|Ensembl:ENSMUSG00000046721 +100040972 Tceal7 MGI:MGI:1915746|Ensembl:ENSMUSG00000079428|Vega:OTTMUSG00000018672 +100040974 LOC100040974 - +100040976 Gm3072 MGI:MGI:3781249 +100040980 Gm3076 MGI:MGI:3781253 +100040981 Gm16429 MGI:MGI:3704105|Ensembl:ENSMUSG00000096230|Vega:OTTMUSG00000055698 +100040983 Gm3077 MGI:MGI:3781254 +100040986 Gm15355 MGI:MGI:3642792 +100040987 Gm15018 MGI:MGI:3705385 +100040990 Gm3081 MGI:MGI:3781258 +100040991 Gm20856 MGI:MGI:5434212 +100040996 Gm3084 MGI:MGI:3781261 +100040997 Gm15340 MGI:MGI:3705158 +100040999 Gm3086 MGI:MGI:3781262|Ensembl:ENSMUSG00000079076 +100041002 Gm3088 MGI:MGI:3781264 +100041003 Gm3089 MGI:MGI:3781265 +100041004 Gm3090 MGI:MGI:3781266 +100041006 Gm11960 MGI:MGI:3652301 +100041007 Gm3091 MGI:MGI:3781267 +100041008 Gm3092 MGI:MGI:3781268 +100041012 Gm3095 MGI:MGI:3781271 +100041013 Gm3096 MGI:MGI:3781272 +100041014 Gm20857 MGI:MGI:5434213 +100041017 Gm14694 MGI:MGI:3705802 +100041019 Gm3099 MGI:MGI:3781275 +100041025 Gm3102 MGI:MGI:3781278 +100041026 Gm12466 MGI:MGI:3651763 +100041027 Gm3103 MGI:MGI:3781279 +100041028 Gm3104 MGI:MGI:3781280 +100041032 Gm3106 MGI:MGI:3781282|Ensembl:ENSMUSG00000096259|Vega:OTTMUSG00000055644 +100041033 Gm20858 MGI:MGI:5434214 +100041034 LOC100041034 - +100041036 Gm11360 MGI:MGI:3649916 +100041038 Gm12467 MGI:MGI:3651688 +100041046 Gm3111 MGI:MGI:3781287 +100041048 Gm12993 MGI:MGI:3650477 +100041054 Gm3115 MGI:MGI:3781291|Ensembl:ENSMUSG00000091022|Vega:OTTMUSG00000036209 +100041056 Gm3116 MGI:MGI:3781292 +100041057 LOC100041057 Ensembl:ENSMUSG00000079190 +100041062 Gm13286 MGI:MGI:3650855 +100041065 Gm3121 MGI:MGI:3781297 +100041069 Gm3123 MGI:MGI:3781299 +100041071 Gm13496 MGI:MGI:3651033 +100041074 Gm3126 MGI:MGI:3781302 +100041076 Gm3127 MGI:MGI:3781303|Ensembl:ENSMUSG00000090764|Vega:OTTMUSG00000036212 +100041077 Gm13102 MGI:MGI:3703005|Ensembl:ENSMUSG00000073723|Vega:OTTMUSG00000010432 +100041080 Gm20859 MGI:MGI:5434215 +100041085 Mfsd4b3 MGI:MGI:3773841|Ensembl:ENSMUSG00000071335|Vega:OTTMUSG00000036503 +100041086 Gm3131 MGI:MGI:3781308 +100041089 Gm3134 MGI:MGI:3781311 +100041092 Gm10238 MGI:MGI:3641620 +100041093 Gm12827 MGI:MGI:3651358 +100041094 Gm3136 MGI:MGI:3781313 +100041095 Vstm1 MGI:MGI:3781314 +100041096 Iqcf6 MGI:MGI:3781315|Ensembl:ENSMUSG00000091129|Vega:OTTMUSG00000049592 +100041098 Tma7-ps MGI:MGI:3705453 +100041099 Gm3137 MGI:MGI:3781316 +100041100 Gm3138 MGI:MGI:3781317 +100041102 Gm3139 MGI:MGI:3781318|Ensembl:ENSMUSG00000095074|Vega:OTTMUSG00000055648 +100041105 Gm3140 MGI:MGI:3781319 +100041106 Gm3141 MGI:MGI:3781320 +100041107 Gm3142 MGI:MGI:3781321 +100041108 Gm3143 MGI:MGI:3781322|Ensembl:ENSMUSG00000105153 +100041110 Gm15016 MGI:MGI:3705629 +100041113 Gm3145 MGI:MGI:3781324 +100041114 Gm3146 MGI:MGI:3781325 +100041115 Gm3147 MGI:MGI:3781326|Ensembl:ENSMUSG00000095503|Vega:OTTMUSG00000055649 +100041116 Gm3148 MGI:MGI:3781327 +100041117 Gm20860 MGI:MGI:5434216 +100041119 Gm3149 MGI:MGI:3781328 +100041120 Gm3150 MGI:MGI:3781329 +100041121 Gm10144 MGI:MGI:3641742 +100041126 Vmn2r-ps2 MGI:MGI:3757651 +100041135 Gm11363 MGI:MGI:3652072 +100041136 Gm3157 MGI:MGI:3781336 +100041137 Gm15930 MGI:MGI:3805554 +100041139 Gm3159 MGI:MGI:3781338|Ensembl:ENSMUSG00000095056|Vega:OTTMUSG00000036219 +100041140 Gm3160 MGI:MGI:3781339 +100041141 Gm20861 MGI:MGI:5434217 +100041142 Gm20862 MGI:MGI:5434218 +100041143 Gm3161 MGI:MGI:3781340 +100041144 Gm13105 MGI:MGI:3650201 +100041146 Gm15448 MGI:MGI:3705216|Ensembl:ENSMUSG00000074419|Vega:OTTMUSG00000022068 +100041147 Gm14717 MGI:MGI:3705148 +100041151 Gm3636 MGI:MGI:3781812|Ensembl:ENSMUSG00000091754|Vega:OTTMUSG00000036152 +100041154 Rpl35a-ps7 MGI:MGI:3781346 +100041155 Cox20-ps MGI:MGI:3783125 +100041163 Rpl23a-ps3 MGI:MGI:3781353 +100041164 Gm13268 MGI:MGI:3651947 +100041166 Gm3176 MGI:MGI:3781355 +100041167 Gm14382 MGI:MGI:3650372 +100041168 Gm20863 MGI:MGI:5434219 +100041177 Gm3182 MGI:MGI:3781361|Ensembl:ENSMUSG00000091148|Vega:OTTMUSG00000036229 +100041179 Gm3183 MGI:MGI:3781362|Ensembl:ENSMUSG00000095954|Vega:OTTMUSG00000055651 +100041183 Gm3186 MGI:MGI:3781365 +100041184 Gm3187 MGI:MGI:3781366 +100041185 Gm3188 MGI:MGI:3781367 +100041186 Gm3189 MGI:MGI:3781368 +100041187 Olfr596 MGI:MGI:3030430|Ensembl:ENSMUSG00000073953|Vega:OTTMUSG00000019046 +100041191 Gm3191 MGI:MGI:3781370 +100041192 Gm3192 MGI:MGI:3781371 +100041194 Ahnak2 MGI:MGI:2144831 +100041196 Gm13344 MGI:MGI:3649239 +100041197 Gm12495 MGI:MGI:3650574 +100041199 Gm3196 MGI:MGI:3781375 +100041201 Gm3198 MGI:MGI:3781377 +100041204 Gm3200 MGI:MGI:3781379 +100041211 Gm10297 MGI:MGI:3642512 +100041215 Gm3208 MGI:MGI:3781387 +100041218 Gm3211 MGI:MGI:3781390 +100041219 Gm10171 MGI:MGI:3704203 +100041223 Gm20865 MGI:MGI:5434221|Ensembl:ENSMUSG00000093848|Vega:OTTMUSG00000042962 +100041224 Gm3213 MGI:MGI:3781392 +100041227 Gm3216 MGI:MGI:3781395 +100041230 Hist1h4m MGI:MGI:2448441|Ensembl:ENSMUSG00000069306|Vega:OTTMUSG00000000446 +100041231 Gm3219 MGI:MGI:3781398 +100041232 Gm13121 MGI:MGI:3650486 +100041235 Gm3221 MGI:MGI:3781400 +100041236 Gm3222 MGI:MGI:3781401 +100041237 Nudc-ps1 MGI:MGI:2142657 +100041239 Gm3225 MGI:MGI:3781404 +100041240 Gm3226 MGI:MGI:3804968 +100041241 Gm3227 MGI:MGI:3781405 +100041244 Gm3230 MGI:MGI:3781408 +100041245 Gm13464 MGI:MGI:3649845 +100041250 Gm3233 MGI:MGI:3781411|Ensembl:ENSMUSG00000094120 +100041251 Gm3234 MGI:MGI:3781412 +100041253 Gm16513 MGI:MGI:2141041|Ensembl:ENSMUSG00000095996|Vega:OTTMUSG00000055671 +100041254 Gm3235 MGI:MGI:3781413 +100041255 Gm20866 MGI:MGI:5434222 +100041256 Gm20867 MGI:MGI:5434223|Ensembl:ENSMUSG00000096898|Vega:OTTMUSG00000046370 +100041257 Gm11371 MGI:MGI:3651829 +100041260 Gm15042 MGI:MGI:3709025 +100041261 Gm3238 MGI:MGI:3781416|Ensembl:ENSMUSG00000095817 +100041262 Gm3239 MGI:MGI:3781417 +100041264 Gm10424 MGI:MGI:3704250|Ensembl:ENSMUSG00000096066|Vega:OTTMUSG00000055672 +100041265 Gm9755 MGI:MGI:3642279 +100041266 Gm11372 MGI:MGI:3651830 +100041268 Gm3242 MGI:MGI:3781420 +100041272 Gm15045 MGI:MGI:3709024 +100041273 Gm3244 MGI:MGI:3781422 +100041276 Gm15388 MGI:MGI:3705340 +100041278 Gm3247 MGI:MGI:3781425 +100041279 Gm3248 MGI:MGI:3781426 +100041281 Gm3250 MGI:MGI:3781428|Ensembl:ENSMUSG00000096481 +100041283 Gm3252 MGI:MGI:3781430 +100041284 Gm20868 MGI:MGI:5434224 +100041286 Snhg15 MGI:MGI:3650059|Ensembl:ENSMUSG00000085156 +100041289 Gm3255 MGI:MGI:3781433 +100041290 D4Ertd617e MGI:MGI:1277206 +100041293 Gm3257 MGI:MGI:3781435 +100041294 Supt4b MGI:MGI:1335090 +100041296 Gm3259 MGI:MGI:3781437|Ensembl:ENSMUSG00000079424|Vega:OTTMUSG00000030874 +100041299 Gm3261 MGI:MGI:3781439 +100041302 Gm13361 MGI:MGI:3651169 +100041303 Gm12480 MGI:MGI:3651952 +100041306 Gm3264 MGI:MGI:3781442|Ensembl:ENSMUSG00000094132 +100041307 Gm15387 MGI:MGI:3705374 +100041309 Gm20869 MGI:MGI:5434225 +100041310 Gm3266 MGI:MGI:3781444 +100041311 Gm11978 MGI:MGI:3650695|Ensembl:ENSMUSG00000086373 +100041312 Gm11378 MGI:MGI:3650784 +100041313 Gm3267 MGI:MGI:3781446 +100041317 Gm3269 MGI:MGI:3781447 +100041318 Gm15342 MGI:MGI:3705188 +100041323 Ly6e-ps1 MGI:MGI:107156 +100041325 Gm3272 MGI:MGI:3781450 +100041328 Gm12540 MGI:MGI:3651849 +100041332 Gm11984 MGI:MGI:3650611 +100041333 Gm3275 MGI:MGI:3781453 +100041336 Gm3278 MGI:MGI:3781456|Ensembl:ENSMUSG00000091185|Vega:OTTMUSG00000036245 +100041337 Gm13465 MGI:MGI:3649598 +100041339 Gm3279 MGI:MGI:3781457|Ensembl:ENSMUSG00000108063 +100041342 Gm12537 MGI:MGI:3650720 +100041344 Gm14686 MGI:MGI:3712656 +100041345 Gm20870 MGI:MGI:5434226|Ensembl:ENSMUSG00000100535|Vega:OTTMUSG00000046095 +100041346 Gm20871 MGI:MGI:5434227|Ensembl:ENSMUSG00000101005 +100041347 Gm11985 MGI:MGI:3650614|Ensembl:ENSMUSG00000087512|Vega:OTTMUSG00000005133 +100041348 Gm12513 MGI:MGI:3649753 +100041349 Gm3283 MGI:MGI:3781461 +100041351 Gm3285 MGI:MGI:3781463|Ensembl:ENSMUSG00000111915 +100041352 Tcp10c MGI:MGI:98543|Ensembl:ENSMUSG00000052469 +100041354 Gm3286 MGI:MGI:3781464|Ensembl:ENSMUSG00000079423|Vega:OTTMUSG00000055674 +100041356 Gm3287 MGI:MGI:3781465 +100041358 Gm3289 MGI:MGI:3781467 +100041359 Gm15190 MGI:MGI:3705630 +100041362 Gm20873 MGI:MGI:5434229|Ensembl:ENSMUSG00000095148|Vega:OTTMUSG00000045671 +100041365 Gm3292 MGI:MGI:3781470 +100041367 Gm3294 MGI:MGI:3781472 +100041370 Gm11387 MGI:MGI:3649582 +100041372 Gm13722 MGI:MGI:3651668 +100041373 Cfap47 MGI:MGI:3781475 +100041374 Gm3298 MGI:MGI:3781476 +100041375 Cyp3a41b MGI:MGI:3714859|Ensembl:ENSMUSG00000075552|Vega:OTTMUSG00000055069 +100041379 Zfp980 MGI:MGI:3712454|Ensembl:ENSMUSG00000058186|Vega:OTTMUSG00000011070 +100041380 Gm3302 MGI:MGI:3781480 +100041381 Gm11667 MGI:MGI:3649871 +100041386 Gm3307 MGI:MGI:3781485 +100041395 Gm3313 MGI:MGI:3781491 +100041399 Gm10327 MGI:MGI:3704356 +100041400 Gm12226 MGI:MGI:3649742 +100041403 Gm15195 MGI:MGI:3705434 +100041405 Gm3318 MGI:MGI:3781496 +100041407 Gm3320 MGI:MGI:3781498 +100041408 Gm3321 MGI:MGI:3781499 +100041411 Gm12225 MGI:MGI:3649520 +100041412 Gm11938 MGI:MGI:3651233|Ensembl:ENSMUSG00000057674|Vega:OTTMUSG00000004968 +100041413 Gm16401 MGI:MGI:3648398 +100041420 Gm3325 MGI:MGI:3781503 +100041421 Gm3326 MGI:MGI:3781504 +100041422 Gm3327 MGI:MGI:3781505 +100041424 Gm3329 MGI:MGI:3781507 +100041426 Gm3331 MGI:MGI:3781509 +100041427 Gm15196 MGI:MGI:3705411 +100041429 Gm3332 MGI:MGI:3781510 +100041430 Gm3333 MGI:MGI:3781511 +100041433 Zfp981 MGI:MGI:3700965|Ensembl:ENSMUSG00000056300|Vega:OTTMUSG00000011075 +100041437 Gm3338 MGI:MGI:3781516 +100041438 Gm3339 MGI:MGI:3781517 +100041440 Gm20874 MGI:MGI:5434230 +100041445 Vmn1r-ps9 MGI:MGI:3781521 +100041446 Gm15046 MGI:MGI:3705253 +100041449 Cyp3a59 MGI:MGI:3769707|Ensembl:ENSMUSG00000061292|Vega:OTTMUSG00000055079 +100041450 Gimap1os MGI:MGI:3781523 +100041459 Gm3351 MGI:MGI:3781529 +100041464 Gm3355 MGI:MGI:3781533 +100041472 Gm3360 MGI:MGI:3781538 +100041474 Gm14754 MGI:MGI:3705517 +100041478 Gm3362 MGI:MGI:3781540 +100041479 Gm3363 MGI:MGI:3781541|Ensembl:ENSMUSG00000092353 +100041480 Gm9833 MGI:MGI:3641855|Ensembl:ENSMUSG00000049230|Vega:OTTMUSG00000051456 +100041481 Gm3364 MGI:MGI:3781542 +100041482 Gm3365 MGI:MGI:3781543 +100041483 LOC100041483 - +100041484 Gm15361 MGI:MGI:3642247 +100041488 Gm11937 MGI:MGI:3651231|Ensembl:ENSMUSG00000058725|Vega:OTTMUSG00000004963 +100041489 Gm3367 MGI:MGI:3781545 +100041490 Gm20875 MGI:MGI:5434231 +100041494 Gm3370 MGI:MGI:3781548 +100041497 Gm3371 MGI:MGI:3781549 +100041498 Gm3372 MGI:MGI:3781550 +100041500 Gm10146 MGI:MGI:3704367 +100041503 Gm3375 MGI:MGI:3781553 +100041504 LOC100041504 Ensembl:ENSMUSG00000094121 +100041505 Gm3376 MGI:MGI:3781554|Ensembl:ENSMUSG00000096520|Vega:OTTMUSG00000045472 +100041509 Gm3379 MGI:MGI:3781557 +100041511 Rpl19-ps11 MGI:MGI:3642193 +100041514 Gm3382 MGI:MGI:3781560 +100041515 Gm3383 MGI:MGI:3781561|Ensembl:ENSMUSG00000096629|Vega:OTTMUSG00000036262 +100041516 LOC100041516 - +100041519 Gm3385 MGI:MGI:3781563 +100041521 Gm3386 MGI:MGI:3781564 +100041530 Gm10409 MGI:MGI:3710610|Ensembl:ENSMUSG00000096488|Vega:OTTMUSG00000036018 +100041536 LOC100041536 - +100041546 Ly6c2 MGI:MGI:3712069|Ensembl:ENSMUSG00000022584|Vega:OTTMUSG00000045164 +100041548 Gm3402 MGI:MGI:3781580|Ensembl:ENSMUSG00000041505|Vega:OTTMUSG00000055160 +100041550 Gm20877 MGI:MGI:5434233|Ensembl:ENSMUSG00000095520|Vega:OTTMUSG00000049721 +100041554 Gm3404 MGI:MGI:3781582|Ensembl:ENSMUSG00000079091|Vega:OTTMUSG00000055161 +100041555 Rpl10-ps5 MGI:MGI:3781583 +100041557 Gm15206 MGI:MGI:3708122 +100041559 Gm11676 MGI:MGI:3650355 +100041561 Gm13142 MGI:MGI:3651745 +100041562 Gm14762 MGI:MGI:3705212 +100041566 Gm3409 MGI:MGI:3781587|Ensembl:ENSMUSG00000096664|Vega:OTTMUSG00000055162 +100041567 Gm10060 MGI:MGI:3710638 +100041569 Gm3411 MGI:MGI:3781589 +100041570 Gm13162 MGI:MGI:3701119 +100041571 Vmn1r-ps18 MGI:MGI:3781590 +100041573 Gm11945 MGI:MGI:3650072 +100041574 9030025P20Rik MGI:MGI:3583895|Ensembl:ENSMUSG00000036552 +100041576 Gm3414 MGI:MGI:3781592|Ensembl:ENSMUSG00000015882 +100041578 Gm3415 MGI:MGI:3781593|Ensembl:ENSMUSG00000095557|Vega:OTTMUSG00000055163 +100041579 Gm20878 MGI:MGI:5434234|Ensembl:ENSMUSG00000078747|Vega:OTTMUSG00000011355 +100041581 Zkscan16 MGI:MGI:3510405|Ensembl:ENSMUSG00000038630|Vega:OTTMUSG00000007625 +100041585 Amd2 MGI:MGI:1333111|Ensembl:ENSMUSG00000063953|Vega:OTTMUSG00000063371 +100041586 Gm3417 MGI:MGI:3781595|Ensembl:ENSMUSG00000079710 +100041588 Gm3418 MGI:MGI:3781596 +100041593 LOC100041593 Ensembl:ENSMUSG00000096271 +100041594 Spin2-ps3 MGI:MGI:3805546 +100041596 Gal3st2b MGI:MGI:3711964|Ensembl:ENSMUSG00000093805|Vega:OTTMUSG00000048692 +100041598 Gm3424 MGI:MGI:3781602|Ensembl:ENSMUSG00000090512 +100041599 LOC100041599 - +100041605 Gm3428 MGI:MGI:3781606|Ensembl:ENSMUSG00000098705 +100041607 Gm15209 MGI:MGI:3705716 +100041614 Gm13491 MGI:MGI:3649404 +100041616 Gm3433 MGI:MGI:3781611 +100041618 Gm3434 MGI:MGI:3781612|Ensembl:ENSMUSG00000098390 +100041621 Gm3435 MGI:MGI:3810125|Ensembl:ENSMUSG00000036552 +100041622 Gm3436 MGI:MGI:3781613 +100041627 Gm3440 MGI:MGI:3781617 +100041631 Gm20879 MGI:MGI:5434235 +100041632 Gm3442 MGI:MGI:3781619 +100041633 Gm3443 MGI:MGI:3781620 +100041637 Vmn1r-ps43 MGI:MGI:3781624 +100041639 Gm3448 MGI:MGI:3809205|Ensembl:ENSMUSG00000079710 +100041642 Spin2-ps4 MGI:MGI:3645574 +100041645 Vmn2r-ps114 MGI:MGI:3761532 +100041649 Mpc1-ps MGI:MGI:3781628 +100041651 Gm3453 MGI:MGI:3781629 +100041652 Gm3454 MGI:MGI:3781630 +100041653 Gm3455 MGI:MGI:3781631 +100041655 Gm10863 MGI:MGI:3641623|Ensembl:ENSMUSG00000075555 +100041658 Mup7 MGI:MGI:3709615|Ensembl:ENSMUSG00000073842|Vega:OTTMUSG00000007428 +100041660 Gm3458 MGI:MGI:3781634 +100041662 Gm20880 MGI:MGI:5434236 +100041664 Gm3460 MGI:MGI:3781636 +100041666 Vmn1r-ps46 MGI:MGI:3781637 +100041670 Gm13522 MGI:MGI:3651428 +100041672 LOC100041672 - +100041673 Gm12008 MGI:MGI:3651319 +100041675 Gm3466 MGI:MGI:3781642 +100041677 Zfp984 MGI:MGI:3651978|Ensembl:ENSMUSG00000078495|Vega:OTTMUSG00000010679 +100041678 Gm3500 MGI:MGI:3781677|Ensembl:ENSMUSG00000096003|Vega:OTTMUSG00000036165 +100041680 Gm3470 MGI:MGI:3781646 +100041682 Gm20881 MGI:MGI:5434237 +100041683 Gm20882 MGI:MGI:5434238 +100041685 Gm15220 MGI:MGI:3705356 +100041686 Gm15427 MGI:MGI:3642341 +100041687 Mup8 MGI:MGI:3709619|Ensembl:ENSMUSG00000078687|Vega:OTTMUSG00000008509 +100041688 Defa35 MGI:MGI:3711900|Ensembl:ENSMUSG00000061845|Vega:OTTMUSG00000018258 +100041689 Gm3473 MGI:MGI:3781649 +100041690 Gm12288 MGI:MGI:3649362 +100041691 Gm15442 MGI:MGI:3705708 +100041694 Gm10451 MGI:MGI:3641898|Ensembl:ENSMUSG00000073000 +100041695 Gm3474 MGI:MGI:3781650 +100041697 Gm14719 MGI:MGI:3705771 +100041698 Gm20883 MGI:MGI:5434239 +100041702 Gm3476 MGI:MGI:3781652|Ensembl:ENSMUSG00000079371|Vega:OTTMUSG00000036176 +100041703 Gm13342 MGI:MGI:3650441 +100041708 LOC100041708 - +100041712 LOC100041712 Ensembl:ENSMUSG00000094474 +100041714 Gm20884 MGI:MGI:5434240 +100041720 Gm11953 MGI:MGI:3649564 +100041722 1700049E17Rik2 MGI:MGI:3796510 +100041724 Gm15217 MGI:MGI:3705233|Ensembl:ENSMUSG00000079261|Vega:OTTMUSG00000019524 +100041727 Gm16412 MGI:MGI:3645317 +100041729 Gm3486 MGI:MGI:3781663 +100041732 Gm15222 MGI:MGI:3705297 +100041734 4930522L14Rik MGI:MGI:1925270|Ensembl:ENSMUSG00000072762|Vega:OTTMUSG00000022585 +100041735 Gm3488 MGI:MGI:3781665|Ensembl:ENSMUSG00000095295|Vega:OTTMUSG00000042525 +100041738 Gm3489 MGI:MGI:3781666 +100041739 1700025D23Rik MGI:MGI:1916667 +100041748 Gm10291 MGI:MGI:3641638 +100041749 Speer4f2 MGI:MGI:3781672|Ensembl:ENSMUSG00000091827|Vega:OTTMUSG00000036601 +100041751 Gm20885 MGI:MGI:5434241 +100041752 Gm3496 MGI:MGI:3781673 +100041754 Gm15219 MGI:MGI:3705294 +100041759 Gm15293 MGI:MGI:3705230|Ensembl:ENSMUSG00000079116|Vega:OTTMUSG00000019786 +100041766 Gm9762 MGI:MGI:3704220 +100041774 Gm10413 MGI:MGI:3704417|Ensembl:ENSMUSG00000095533|Vega:OTTMUSG00000036017 +100041775 Gm3507 MGI:MGI:3781684 +100041776 Gm20886 MGI:MGI:5434242 +100041778 Gm3508 MGI:MGI:3781685 +100041779 Gm3509 MGI:MGI:3781686 +100041781 Gm3510 MGI:MGI:3781687 +100041785 Gm16399 MGI:MGI:3645963 +100041786 Gm3511 MGI:MGI:3781688 +100041787 Gm15292 MGI:MGI:3708769|Ensembl:ENSMUSG00000074441|Vega:OTTMUSG00000019784 +100041788 Gm14620 MGI:MGI:3705421 +100041789 Gm20887 MGI:MGI:5434243 +100041790 Gm12293 MGI:MGI:3650726 +100041791 Gm3512 MGI:MGI:3781689 +100041792 Gm14034 MGI:MGI:3651833 +100041795 Vmn2r-ps155 MGI:MGI:3761715 +100041796 Gm14206 MGI:MGI:3649549 +100041805 Gm3519 MGI:MGI:3781696 +100041806 LOC100041806 Ensembl:ENSMUSG00000094887 +100041809 Gm3521 MGI:MGI:3781698 +100041811 Defa27 MGI:MGI:3642780|Ensembl:ENSMUSG00000082211 +100041812 Gm20888 MGI:MGI:5434244 +100041813 Gm20889 MGI:MGI:5434245 +100041814 Gm3523 MGI:MGI:3781700 +100041817 Gm3526 MGI:MGI:3781703 +100041818 Gm3527 MGI:MGI:3781704 +100041819 Gm10167 MGI:MGI:3704263 +100041821 Gm3529 MGI:MGI:3781706 +100041822 Gm3530 MGI:MGI:3781707 +100041823 Gm3531 MGI:MGI:3781708 +100041825 Gm3532 MGI:MGI:3781709 +100041826 Gm10182 MGI:MGI:3704327 +100041831 Gm3534 MGI:MGI:3781711 +100041835 Gm10039 MGI:MGI:3704382 +100041840 Gm10408 MGI:MGI:3704423|Ensembl:ENSMUSG00000072739|Vega:OTTMUSG00000036174 +100041843 Defa-ps18 MGI:MGI:3642785 +100041847 Vmn2r-ps157 MGI:MGI:3761717 +100041849 Gm3543 MGI:MGI:3781720 +100041850 Gm3544 MGI:MGI:3781721 +100041854 Gm3546 MGI:MGI:3781723 +100041855 Vmn2r-ps100 MGI:MGI:3761519 +100041856 Gm3547 MGI:MGI:3781724 +100041858 Gm3549 MGI:MGI:3781726 +100041859 Gm3550 MGI:MGI:3781727 +100041863 Gm3551 MGI:MGI:3781728 +100041864 Gm3552 MGI:MGI:3781729 +100041868 Gm3555 MGI:MGI:3781732 +100041869 Gm15407 MGI:MGI:3705245 +100041870 Gm3556 MGI:MGI:3781733 +100041874 Gm3558 MGI:MGI:3781735|Ensembl:ENSMUSG00000079364|Vega:OTTMUSG00000035723 +100041877 LOC100041877 - +100041879 Gm3561 MGI:MGI:3781738 +100041882 Gm13094 MGI:MGI:3650867 +100041883 Gm3563 MGI:MGI:3781740 +100041886 Gm3565 MGI:MGI:3781742 +100041890 Defa32 MGI:MGI:3709042|Ensembl:ENSMUSG00000094818|Vega:OTTMUSG00000019860 +100041892 Vmn2r-ps102 MGI:MGI:3761521 +100041895 Defa37 MGI:MGI:3705236|Ensembl:ENSMUSG00000065956|Vega:OTTMUSG00000018259 +100041897 Gm20890 MGI:MGI:5434246 +100041900 Gm13526 MGI:MGI:3651219 +100041903 LOC100041903 - +100041907 Gm3571 MGI:MGI:3781748 +100041910 Gm3573 MGI:MGI:3781750 +100041912 Gm15226 MGI:MGI:3705187 +100041913 Gm20891 MGI:MGI:5434247 +100041915 Vmn2r-ps104 MGI:MGI:3761523 +100041918 Gm13529 MGI:MGI:3649710 +100041922 Gm20892 MGI:MGI:5434248 +100041923 Gm13728 MGI:MGI:3652180 +100041925 Gm14586 MGI:MGI:3705507|Ensembl:ENSMUSG00000083621 +100041926 Gm15393 MGI:MGI:3705387 +100041927 Gm3577 MGI:MGI:3781754 +100041931 Gm13403 MGI:MGI:3649380 +100041932 Gm3579 MGI:MGI:3781756 +100041934 Gm20893 MGI:MGI:5434249 +100041938 Vmn2r-ps106 MGI:MGI:3761525 +100041942 Gm3584 MGI:MGI:3781761 +100041947 Vmn2r-ps108 MGI:MGI:3761527 +100041948 Gm9800 MGI:MGI:3710580 +100041949 Gm3585 MGI:MGI:3781762 +100041951 Gm3587 MGI:MGI:3781764 +100041952 Defa34 MGI:MGI:3709048|Ensembl:ENSMUSG00000063206|Vega:OTTMUSG00000019924 +100041953 Sap18b MGI:MGI:3704317|Ensembl:ENSMUSG00000061104|Vega:OTTMUSG00000061797 +100041958 Gm3591 MGI:MGI:3781768|Ensembl:ENSMUSG00000096904|Vega:OTTMUSG00000036146 +100041960 9230110K08Rik MGI:MGI:1925157 +100041964 Gm3594 MGI:MGI:3781771|Ensembl:ENSMUSG00000095360|Vega:OTTMUSG00000036160 +100041965 Oaz1-ps MGI:MGI:108188 +100041966 Gm20894 MGI:MGI:5434250 +100041968 Gm3596 MGI:MGI:3781773 +100041971 Gm3598 MGI:MGI:3781775 +100041973 Gm20895 MGI:MGI:5434251 +100041979 Gm3604 MGI:MGI:3781781|Ensembl:ENSMUSG00000094942|Vega:OTTMUSG00000046852 +100041981 Gm3605 MGI:MGI:3781782 +100041985 Gm3608 MGI:MGI:3804932 +100041986 Gm3609 MGI:MGI:3781785 +100041987 Gm20896 MGI:MGI:5434252 +100041989 Gm3589 MGI:MGI:3781766 +100041990 Gm13259 MGI:MGI:3700962 +100041994 Gm12307 MGI:MGI:3651667 +100041998 Gm3616 MGI:MGI:3781792 +100041999 Gm3617 MGI:MGI:3781793 +100042000 Gm3618 MGI:MGI:3781794 +100042001 Gm14750 MGI:MGI:3705827 +100042004 Gm3619 MGI:MGI:3781795 +100042006 Gm3621 MGI:MGI:3781797 +100042008 Gm9794 MGI:MGI:3642653|Ensembl:ENSMUSG00000107176 +100042009 Gm3623 MGI:MGI:3781799 +100042012 Gm20897 MGI:MGI:5434253 +100042013 Gm20898 MGI:MGI:5434254 +100042014 Gm3625 MGI:MGI:3781801 +100042017 Gm11341 MGI:MGI:3652095 +100042018 Gm3627 MGI:MGI:3781803 +100042019 LOC100042019 - +100042023 Gm10193 MGI:MGI:3708520 +100042024 Gm3629 MGI:MGI:3781805|Ensembl:ENSMUSG00000094590|Vega:OTTMUSG00000042538 +100042025 Gapdh-ps15 MGI:MGI:5434255 +100042027 Gm3631 MGI:MGI:3781807 +100042031 Gm3633 MGI:MGI:3781809 +100042035 Gm12038 MGI:MGI:3651601 +100042036 Gm11728 MGI:MGI:3650943 +100042038 Gm13740 MGI:MGI:3649209 +100042039 Vmn2r-ps42 MGI:MGI:3757871 +100042040 Gm3635 MGI:MGI:3781811 +100042041 Gm15164 MGI:MGI:3705696 +100042045 Gm3637 MGI:MGI:3781813 +100042049 Gm15421 MGI:MGI:3705475 +100042054 Gm3194 MGI:MGI:3781373 +100042055 Gm10377 MGI:MGI:3704431|Ensembl:ENSMUSG00000095226|Vega:OTTMUSG00000036357 +100042056 9130019P16Rik MGI:MGI:1918824|Ensembl:ENSMUSG00000073067 +100042057 Gm3643 MGI:MGI:3781819 +100042058 Gm20900 MGI:MGI:5434256 +100042060 Gm3644 MGI:MGI:3781820 +100042062 Gm15165 MGI:MGI:3705368 +100042065 Gm3646 MGI:MGI:3781822|Ensembl:ENSMUSG00000091937|Vega:OTTMUSG00000050279 +100042067 Rpl17-ps5 MGI:MGI:3704246 +100042069 Impdh2-ps MGI:MGI:3705743|Ensembl:ENSMUSG00000071041 +100042071 Gm15432 MGI:MGI:3801969 +100042074 Gm3650 MGI:MGI:3781826 +100042076 Gm13742 MGI:MGI:3650803 +100042077 Gm10251 MGI:MGI:3704424 +100042079 Gm20901 MGI:MGI:5434257 +100042080 Gm20902 MGI:MGI:5434258 +100042081 Gm12046 MGI:MGI:3651839 +100042083 Gm3654 MGI:MGI:3781830 +100042087 Gm3657 MGI:MGI:3781833 +100042091 Rpl28-ps2 MGI:MGI:3781837 +100042094 Rps27a-ps1 MGI:MGI:3781839 +100042096 Gm3665 MGI:MGI:3781841 +100042098 Gm14825 MGI:MGI:3705704 +100042100 Gm3667 MGI:MGI:3781843 +100042101 Gm3668 MGI:MGI:3781844 +100042103 Gm3669 MGI:MGI:3781845 +100042107 Gm3671 MGI:MGI:3781847 +100042109 Gm10488 MGI:MGI:3710522|Ensembl:ENSMUSG00000073257|Vega:OTTMUSG00000017039 +100042110 Gm20903 MGI:MGI:5434259|Ensembl:ENSMUSG00000099782|Vega:OTTMUSG00000046206 +100042113 Gm3675 MGI:MGI:3781851 +100042114 Gm3676 MGI:MGI:3781852 +100042118 Gm3678 MGI:MGI:3781854 +100042122 Gm3681 MGI:MGI:3781857 +100042125 Gm15535 MGI:MGI:3782983 +100042126 Gm3683 MGI:MGI:3781859 +100042129 Gm3685 MGI:MGI:3781861|Ensembl:ENSMUSG00000094021 +100042130 Gm10376 MGI:MGI:3704432 +100042132 Gm12371 MGI:MGI:3652322 +100042133 Gm3687 MGI:MGI:3781863 +100042139 Gm3690 MGI:MGI:3781866 +100042143 Gm3693 MGI:MGI:3781869 +100042144 Gm14632 MGI:MGI:3805544|Ensembl:ENSMUSG00000073255|Vega:OTTMUSG00000017531 +100042146 Rpsa-ps3 MGI:MGI:3652081 +100042148 Gm3695 MGI:MGI:3781871 +100042149 Gm3696 MGI:MGI:3781872|Ensembl:ENSMUSG00000092167|Vega:OTTMUSG00000035708 +100042150 Nrg2 MGI:MGI:1098246|Ensembl:ENSMUSG00000060275|Vega:OTTMUSG00000014928 +100042159 Btbd35f16 MGI:MGI:3781877|Ensembl:ENSMUSG00000101381|Vega:OTTMUSG00000019618 +100042163 Gm3702 MGI:MGI:3781878 +100042165 BC005561 MGI:MGI:3040669|Ensembl:ENSMUSG00000079065|Vega:OTTMUSG00000053777 +100042166 Gm3704 MGI:MGI:3781880|Ensembl:ENSMUSG00000097321 +100042168 Btbd35f3 MGI:MGI:3781882|Ensembl:ENSMUSG00000078218|Vega:OTTMUSG00000019621 +100042171 Gm10161 MGI:MGI:3642846 +100042172 Vmn2r-ps149 MGI:MGI:3761709 +100042173 Rps15a-ps6 MGI:MGI:3650298 +100042174 Gm12882 MGI:MGI:3651897 +100042175 Gm10230 MGI:MGI:3710515|Ensembl:ENSMUSG00000095546|Vega:OTTMUSG00000017018 +100042178 Gm13111 MGI:MGI:3651882|Ensembl:ENSMUSG00000085069 +100042179 Gm9803 MGI:MGI:3704359 +100042180 Gm11353 MGI:MGI:3649794 +100042182 Gm16434 MGI:MGI:3646563|Ensembl:ENSMUSG00000095015|Vega:OTTMUSG00000035711 +100042185 Gm14349 MGI:MGI:3650762 +100042188 Gm3711 MGI:MGI:3781887 +100042189 Gm3712 MGI:MGI:3781888 +100042192 Gm3715 MGI:MGI:3781891 +100042194 Gm13446 MGI:MGI:3649869|Ensembl:ENSMUSG00000086555 +100042195 Gm20905 MGI:MGI:5434261 +100042198 Gm3716 MGI:MGI:3781892|Ensembl:ENSMUSG00000105402 +100042201 Gm20906 MGI:MGI:5434262|Ensembl:ENSMUSG00000099856|Vega:OTTMUSG00000047138 +100042202 Gm3718 MGI:MGI:3781894 +100042203 Gm3719 MGI:MGI:3781895 +100042204 Gm3720 MGI:MGI:3781896 +100042211 Gm3724 MGI:MGI:3804937 +100042214 Gm3726 MGI:MGI:3781901 +100042217 Gm3727 MGI:MGI:3781902 +100042218 Gm3728 MGI:MGI:3781903 +100042225 Vmn2r-ps130 MGI:MGI:3761689 +100042226 Gm3734 MGI:MGI:3781909 +100042235 Gm3739 MGI:MGI:3781914 +100042237 Gm3740 MGI:MGI:3781915 +100042239 Gm3742 MGI:MGI:3781917 +100042241 Gm3744 MGI:MGI:3781919 +100042242 Gm3745 MGI:MGI:3781920 +100042244 Gm9836 MGI:MGI:3642194 +100042248 Gm3748 MGI:MGI:3781923 +100042251 Gm3749 MGI:MGI:3781924 +100042253 Gm10043 MGI:MGI:3641648 +100042254 Btbd35f4 MGI:MGI:3781925|Ensembl:ENSMUSG00000078213|Vega:OTTMUSG00000019617 +100042256 Gm12063 MGI:MGI:3649572 +100042258 Gm3752 MGI:MGI:3781927 +100042263 Gm3755 MGI:MGI:3781930 +100042265 Gm9790 MGI:MGI:3704221 +100042266 Gm3756 MGI:MGI:3781931 +100042267 Gm3757 MGI:MGI:3781932 +100042268 Gm20907 MGI:MGI:5434263 +100042272 Gm3760 MGI:MGI:3781934 +100042275 Btbd35f27 MGI:MGI:3781937|Ensembl:ENSMUSG00000094860|Vega:OTTMUSG00000042959 +100042277 Gm3764 MGI:MGI:3781938 +100042278 Gm3765 MGI:MGI:3781939 +100042279 Gm20908 MGI:MGI:5434264|Ensembl:ENSMUSG00000101766|Vega:OTTMUSG00000045740 +100042282 Gm12665 MGI:MGI:3652165 +100042291 Gm3772 MGI:MGI:3781946|Ensembl:ENSMUSG00000113074 +100042293 Gm3774 MGI:MGI:3781948 +100042294 Gm3775 MGI:MGI:3781949 +100042295 Gm3776 MGI:MGI:3826440|Ensembl:ENSMUSG00000111709|Vega:OTTMUSG00000062953 +100042299 Gm3778 MGI:MGI:3781951 +100042304 Gm38418 MGI:MGI:5621303 +100042305 Gm12396 MGI:MGI:3649201 +100042311 Gm3785 MGI:MGI:3781958 +100042312 Gm10128 MGI:MGI:3704427 +100042313 Gm3786 MGI:MGI:3781959 +100042314 Gm10639 MGI:MGI:3704339|Ensembl:ENSMUSG00000074179|Vega:OTTMUSG00000019693 +100042318 Gm3787 MGI:MGI:3781960 +100042319 Gm3788 MGI:MGI:3781961 +100042321 Gm20909 MGI:MGI:5434265 +100042324 Gm14815 MGI:MGI:3705483 +100042325 Gm3791 MGI:MGI:3781964 +100042327 Gm3793 MGI:MGI:3781966 +100042332 2810410L24Rik MGI:MGI:1923627 +100042335 Rps15a-ps5 MGI:MGI:3642245|Ensembl:ENSMUSG00000067058 +100042337 Gm20910 MGI:MGI:5434266 +100042342 Gm10375 MGI:MGI:3704433|Ensembl:ENSMUSG00000095528|Vega:OTTMUSG00000036384 +100042347 Gm3800 MGI:MGI:3781973 +100042348 Gm10221 MGI:MGI:3708709 +100042349 Gm10359 MGI:MGI:3708724 +100042350 Gm14766 MGI:MGI:3705649 +100042355 Gm10705 MGI:MGI:3708678 +100042357 Gm20911 MGI:MGI:5434267 +100042363 Rpl35a-ps2 MGI:MGI:3705461 +100042364 Gm3805 MGI:MGI:3781978 +100042367 Gm12074 MGI:MGI:3650755 +100042371 Gm3807 MGI:MGI:3781980 +100042372 Trav2 MGI:MGI:3642679|IMGT/GENE-DB:TRAV2 +100042374 Gm15504 MGI:MGI:3782951 +100042375 Gm3809 MGI:MGI:3781982 +100042377 Gm3810 MGI:MGI:3781983 +100042384 Trav4-1 MGI:MGI:3781986|IMGT/GENE-DB:TRAV4-1 +100042385 Gm3815 MGI:MGI:3781987 +100042386 Gm3816 MGI:MGI:3781988 +100042388 Gm11361 MGI:MGI:3649931 +100042391 Gm20912 MGI:MGI:5434268 +100042392 Gm3820 MGI:MGI:3781992 +100042393 Gm3821 MGI:MGI:3781993 +100042394 Gm3822 MGI:MGI:3781994 +100042395 Gm20913 MGI:MGI:5434269 +100042401 Gm20914 MGI:MGI:5434270 +100042403 Gm3828 MGI:MGI:3782000 +100042404 Gm3829 MGI:MGI:3782001 +100042405 Gm10282 MGI:MGI:3704312 +100042408 Gm3830 MGI:MGI:3782002 +100042409 Gm20915 MGI:MGI:5434271 +100042410 Trav7d-2 MGI:MGI:3711992|IMGT/GENE-DB:TRAV7D-2 +100042411 Gm3831 MGI:MGI:3782003 +100042415 Mnd1-ps MGI:MGI:3782005 +100042416 D830025C05Rik MGI:MGI:3698180 +100042417 Gm20916 MGI:MGI:5434272|Ensembl:ENSMUSG00000094746|Vega:OTTMUSG00000046633 +100042419 Trav7d-3 MGI:MGI:3649861|IMGT/GENE-DB:TRAV7D-3 +100042421 Gm3835 MGI:MGI:3782007 +100042423 Gm3836 MGI:MGI:3782008 +100042424 Pdcd5-ps MGI:MGI:3782009 +100042426 Gm3838 MGI:MGI:3782010 +100042427 Gm3839 MGI:MGI:3782011 +100042428 Gm20917 MGI:MGI:5434273|Ensembl:ENSMUSG00000095867|Vega:OTTMUSG00000046619 +100042431 Gm3841 MGI:MGI:3782013 +100042434 Gm3844 MGI:MGI:3782016 +100042435 Gm20918 MGI:MGI:5434274 +100042437 Vmn1r79 MGI:MGI:3704282|Ensembl:ENSMUSG00000096735|Vega:OTTMUSG00000038256 +100042440 Gm20919 MGI:MGI:5434275 +100042441 Gm3848 MGI:MGI:3782020 +100042442 Gm10105 MGI:MGI:3641746 +100042443 Gm20920 MGI:MGI:5434276 +100042444 Trav6d-6 MGI:MGI:2686066|IMGT/GENE-DB:TRAV6D-6 +100042446 Vmn1r-ps65 MGI:MGI:3782022 +100042447 Gm3851 MGI:MGI:3782023 +100042448 Gm12623 MGI:MGI:3650566 +100042450 Smim17 MGI:MGI:4365374|Ensembl:ENSMUSG00000093536|Vega:OTTMUSG00000033414 +100042453 Gm3852 MGI:MGI:3782024 +100042457 Gm3853 MGI:MGI:3782025 +100042458 Gm15478 MGI:MGI:3705145 +100042465 Gm3858 MGI:MGI:3782030 +100042466 Gm10601 MGI:MGI:3708690 +100042469 Gm12104 MGI:MGI:3650164 +100042470 Trav3d-2 MGI:MGI:3782032|IMGT/GENE-DB:TRAV3D-2 +100042471 Gm3861 MGI:MGI:3782033 +100042472 Gm10600 MGI:MGI:3710628 +100042475 Gm20921 MGI:MGI:5434277 +100042479 Trav4d-3 MGI:MGI:3782037|IMGT/GENE-DB:TRAV4D-3 +100042480 Nhsl2 MGI:MGI:3645090|Ensembl:ENSMUSG00000079481|Vega:OTTMUSG00000018290 +100042484 4732419C18Rik MGI:MGI:3045379 +100042485 Gm3867 MGI:MGI:3782040 +100042493 Ccl21b MGI:MGI:1349182|Ensembl:ENSMUSG00000095675 +100042497 Gm3871 MGI:MGI:3782044 +100042498 Mir22hg MGI:MGI:1914348|Ensembl:ENSMUSG00000085148 +100042499 Vmn2r55 MGI:MGI:3757950|Ensembl:ENSMUSG00000091045|Vega:OTTMUSG00000038270 +100042503 Gm3873 MGI:MGI:3782046 +100042507 Gm3875 MGI:MGI:3782048 +100042509 Gm20923 MGI:MGI:5434279 +100042510 Gm3877 MGI:MGI:3782050 +100042512 Gm20924 MGI:MGI:5434280 +100042513 Gm3878 MGI:MGI:3782051 +100042514 Sprr2a3 MGI:MGI:3845028|Ensembl:ENSMUSG00000074445|Vega:OTTMUSG00000046796 +100042516 Gm3880 MGI:MGI:3782053 +100042517 Gm3881 MGI:MGI:3782054 +100042519 Gm3883 MGI:MGI:3823028 +100042524 Gm13303 MGI:MGI:3705775 +100042529 Gm3888 MGI:MGI:3782061 +100042530 Gm3889 MGI:MGI:3782062 +100042533 Gm11578 MGI:MGI:3650505 +100042534 Gm3890 MGI:MGI:3782063 +100042536 Gm3892 MGI:MGI:3782065 +100042537 Gm20925 MGI:MGI:5434281 +100042539 Gm3893 MGI:MGI:3782066 +100042542 Gm12007 MGI:MGI:3651318 +100042543 Gm3895 MGI:MGI:3782068 +100042545 Gm3896 MGI:MGI:3782069 +100042547 Gm3897 MGI:MGI:3782070 +100042548 Gm3898 MGI:MGI:3809204 +100042550 Gm20926 MGI:MGI:5434282 +100042554 Gm3902 MGI:MGI:3782074|Ensembl:ENSMUSG00000019857 +100042555 Gm13305 MGI:MGI:3801997|Ensembl:ENSMUSG00000073876|Vega:OTTMUSG00000011351 +100042557 Gm10086 MGI:MGI:3642342 +100042560 Trav11n MGI:MGI:3782076|IMGT/GENE-DB:TRAV11N +100042561 Gm10177 MGI:MGI:3704330 +100042563 Gm20927 MGI:MGI:5434283 +100042565 Gm20928 MGI:MGI:5434284 +100042566 Gm11591 MGI:MGI:3652105 +100042567 Gm3905 MGI:MGI:3782077 +100042568 Trav13n-1 MGI:MGI:5009926|IMGT/GENE-DB:TRAV13N-1 +100042570 Gm16439 MGI:MGI:3647611 +100042571 Gm3907 MGI:MGI:3782080 +100042574 Trav3n-2 MGI:MGI:3782082|IMGT/GENE-DB:TRAV3N-2 +100042577 Gm3912 MGI:MGI:3782085 +100042578 Gm20929 MGI:MGI:5434285|Ensembl:ENSMUSG00000100045|Vega:OTTMUSG00000048584 +100042579 Trav4n-3 MGI:MGI:3782086|IMGT/GENE-DB:TRAV4N-3 +100042580 Rpsa-ps6 MGI:MGI:3782087 +100042583 Gm10268 MGI:MGI:3642637 +100042584 Gm16523 MGI:MGI:4360990|Ensembl:ENSMUSG00000082315 +100042585 Gm20930 MGI:MGI:5434286 +100042588 Gm3916 MGI:MGI:3782090 +100042591 Vmn2r31 MGI:MGI:3757688|Ensembl:ENSMUSG00000096373|Vega:OTTMUSG00000037809 +100042593 Trav13n-2 MGI:MGI:3642345|IMGT/GENE-DB:TRAV13N-2 +100042594 Gm20931 MGI:MGI:5434287|Ensembl:ENSMUSG00000094570|Vega:OTTMUSG00000048641 +100042597 Gm3919 MGI:MGI:3782093 +100042601 Gm3922 MGI:MGI:3782096 +100042603 Gm3924 MGI:MGI:3782098 +100042604 Gm13453 MGI:MGI:3651618 +100042605 Rbakdn MGI:MGI:3782099|Ensembl:ENSMUSG00000104529 +100042606 Gm3926 MGI:MGI:3782100 +100042607 Trav4n-4 MGI:MGI:3704439|IMGT/GENE-DB:TRAV4N-4 +100042609 Gm3927 MGI:MGI:3782101 +100042610 Gm3928 MGI:MGI:3782102 +100042614 Trav5n-4 MGI:MGI:3704440|IMGT/GENE-DB:TRAV5N-4 +100042615 Gm3931 MGI:MGI:3782105 +100042619 Gm20932 MGI:MGI:5434288 +100042621 Gm10904 MGI:MGI:3704441 +100042622 Gm9795 MGI:MGI:3704361 +100042623 Gm3933 MGI:MGI:3782107 +100042624 Sult2a-ps1 MGI:MGI:3705847 +100042625 Gstp-ps MGI:MGI:3782108 +100042633 Gm3939 MGI:MGI:3782113 +100042634 Gm3940 MGI:MGI:3782114 +100042636 Vmn2r34 MGI:MGI:3757700|Ensembl:ENSMUSG00000070841|Vega:OTTMUSG00000037843 +100042639 Gm3942 MGI:MGI:3782116 +100042640 Gm3943 MGI:MGI:3782117 +100042641 Gm3944 MGI:MGI:3782118 +100042642 Gm3945 MGI:MGI:3782119 +100042643 Gm3946 MGI:MGI:3782120 +100042644 Gm12013 MGI:MGI:3651371 +100042648 Gm3948 MGI:MGI:3782122 +100042649 Gm20933 MGI:MGI:5434289 +100042650 Gm10095 MGI:MGI:3642130 +100042651 Tubb4b-ps1 MGI:MGI:3642800 +100042653 Vmn2r36 MGI:MGI:3757866|Ensembl:ENSMUSG00000091651|Vega:OTTMUSG00000037855 +100042659 Gm3952 MGI:MGI:3782126 +100042660 Gm3953 MGI:MGI:3782127 +100042661 Gm13478 MGI:MGI:3651984 +100042662 Vmn2r-ps49 MGI:MGI:3757889 +100042663 1700003E24Rik MGI:MGI:1916607|Ensembl:ENSMUSG00000095110 +100042669 Gm20934 MGI:MGI:5434290 +100042670 Rpl28-ps1 MGI:MGI:3705349 +100042671 Gm15335 MGI:MGI:3705562 +100042673 Gm3956 MGI:MGI:3782130 +100042674 Gm11197 MGI:MGI:3649684 +100042677 Obox4-ps8 MGI:MGI:3782133 +100042678 Gm3960 MGI:MGI:3782134 +100042679 Gm16386 MGI:MGI:3646848 +100042680 Gm3961 MGI:MGI:3782135 +100042681 Gm3962 MGI:MGI:3782136 +100042682 Gm20935 MGI:MGI:5434291 +100042683 Gm3963 MGI:MGI:3782137 +100042685 Obox4-ps9 MGI:MGI:3782139 +100042688 Gm10302 MGI:MGI:3704281 +100042689 Gm20936 MGI:MGI:5434292 +100042690 Gm13769 MGI:MGI:3710598|Ensembl:ENSMUSG00000089859|Vega:OTTMUSG00000014278 +100042691 Obox4-ps11 MGI:MGI:3782142 +100042693 Gm3970 MGI:MGI:3782144 +100042695 Gm3972 MGI:MGI:3782146 +100042697 Gm11200 MGI:MGI:3649950 +100042698 Gm3973 MGI:MGI:3800304 +100042702 Obox4-ps12 MGI:MGI:3782150 +100042703 Gm3978 MGI:MGI:3782151 +100042707 Obox4-ps13 MGI:MGI:3782153 +100042708 Gm12027 MGI:MGI:3651189 +100042709 Gm20937 MGI:MGI:5434293 +100042711 Obox4-ps14 MGI:MGI:3782154 +100042712 Gm3982 MGI:MGI:3782155 +100042714 Obox4-ps15 MGI:MGI:3782157 +100042715 Gm3985 MGI:MGI:3782158 +100042717 Obox4-ps16 MGI:MGI:3782160 +100042719 Gm13509 MGI:MGI:3649640 +100042721 Obox4-ps17 MGI:MGI:3782163 +100042727 Gm3993 MGI:MGI:3782167 +100042728 Obox4-ps18 MGI:MGI:3782168 +100042731 Obox4-ps19 MGI:MGI:3782170 +100042734 Gm10073 MGI:MGI:3641908 +100042735 Obox4-ps20 MGI:MGI:3782172 +100042739 Obox4-ps21 MGI:MGI:3782175 +100042740 Rpl31-ps9 MGI:MGI:3704195 +100042742 Obox4-ps22 MGI:MGI:3782177 +100042744 Gm15458 MGI:MGI:3705291 +100042745 Gm15790 MGI:MGI:3783232 +100042746 Gm12033 MGI:MGI:3650772 +100042753 Obox4-ps27 MGI:MGI:3641735 +100042754 Gm4011 MGI:MGI:3782185 +100042755 Gm4012 MGI:MGI:3782186 +100042756 Obox4-ps28 MGI:MGI:3641736 +100042757 Gm4013 MGI:MGI:3782187 +100042758 Obox4-ps29 MGI:MGI:3782188 +100042761 Gm10697 MGI:MGI:3710527|Ensembl:ENSMUSG00000095251|Vega:OTTMUSG00000052075 +100042762 Obox4-ps30 MGI:MGI:3782190 +100042763 Gm4017 MGI:MGI:3782191 +100042765 Obox4-ps31 MGI:MGI:3782192 +100042767 Gm16415 MGI:MGI:3647855 +100042770 Gm4022 MGI:MGI:3782196 +100042771 Obox4-ps33 MGI:MGI:3782197 +100042772 Gm14881 MGI:MGI:3705701 +100042773 Tmed10-ps MGI:MGI:3782198 +100042775 Gm4026 MGI:MGI:3782200 +100042776 Gm4027 MGI:MGI:3782201|Ensembl:ENSMUSG00000092019|Vega:OTTMUSG00000042991 +100042777 Gm10131 MGI:MGI:3704308 +100042781 Vmn2r40 MGI:MGI:3757872|Ensembl:ENSMUSG00000090864|Vega:OTTMUSG00000037998 +100042782 Fthl17d MGI:MGI:3713070|Ensembl:ENSMUSG00000078206|Vega:OTTMUSG00000016694 +100042784 Prdm11 MGI:MGI:2685553|Ensembl:ENSMUSG00000075028|Vega:OTTMUSG00000014494 +100042785 Cldn25-ps MGI:MGI:3642767 +100042786 Gm16381 MGI:MGI:3648256|Ensembl:ENSMUSG00000113489 +100042788 Gm4032 MGI:MGI:3782206 +100042791 Rps18-ps3 MGI:MGI:3642474 +100042792 Gm4034 MGI:MGI:3782208 +100042793 Gm15234 MGI:MGI:3705137 +100042794 Gm4035 MGI:MGI:3782209 +100042795 2810047C21Rik2 MGI:MGI:3806617 +100042796 Gm4036 MGI:MGI:3782210 +100042797 Gm4037 MGI:MGI:3782211 +100042799 Gm12286 MGI:MGI:3649467 +100042801 Gm15264 MGI:MGI:3705845 +100042802 AI463229 MGI:MGI:2145255 +100042806 Gm4042 MGI:MGI:3782217 +100042807 Eif3j2 MGI:MGI:3704486|Ensembl:ENSMUSG00000043424|Vega:OTTMUSG00000042329 +100042810 Vmn2r45 MGI:MGI:3757883|Ensembl:ENSMUSG00000090662|Vega:OTTMUSG00000042472 +100042811 Mrps36-ps2 MGI:MGI:3704298 +100042812 Rps26-ps1 MGI:MGI:3704322 +100042814 Apol7d MGI:MGI:3723449|Ensembl:ENSMUSG00000073652 +100042816 Gm4045 MGI:MGI:3782220 +100042819 Gm4047 MGI:MGI:3782222 +100042823 Rpl9-ps6 MGI:MGI:3642682 +100042824 Rpl35a-ps6 MGI:MGI:3704258 +100042827 Gm12052 MGI:MGI:3652305 +100042828 Gm4052 MGI:MGI:3782227 +100042831 Gm14868 MGI:MGI:3705519 +100042832 Rpl9-ps4 MGI:MGI:3704410 +100042834 Gm4055 MGI:MGI:3782230 +100042836 Gm4057 MGI:MGI:3782232 +100042837 Gm15644 MGI:MGI:3783088 +100042840 H2al2b MGI:MGI:3710623|Ensembl:ENSMUSG00000095573 +100042841 Gm4059 MGI:MGI:3782234 +100042843 Gm13798 MGI:MGI:3652036 +100042846 Gm12057 MGI:MGI:3650030 +100042848 Vmn2r41 MGI:MGI:3757876|Ensembl:ENSMUSG00000090892|Vega:OTTMUSG00000042464 +100042849 Gm4064 MGI:MGI:3782239|Ensembl:ENSMUSG00000102053|Vega:OTTMUSG00000045388 +100042850 Gm4065 MGI:MGI:3782240 +100042851 Gm4066 MGI:MGI:3782241 +100042855 Gm10267 MGI:MGI:3642556|Ensembl:ENSMUSG00000069385|Vega:OTTMUSG00000042845 +100042856 Gm4070 MGI:MGI:3782245|Ensembl:ENSMUSG00000078606|Vega:OTTMUSG00000040007 +100042859 Gm4073 MGI:MGI:3782248 +100042862 Gm4076 MGI:MGI:3782251 +100042864 Gm10263 MGI:MGI:3642825 +100042866 Rps25-ps1 MGI:MGI:3642902 +100042869 Gm4081 MGI:MGI:3782256 +100042871 Gm4083 MGI:MGI:3782258 +100042872 Gm10112 MGI:MGI:3800293 +100042874 Gm10256 MGI:MGI:3710530|Ensembl:ENSMUSG00000095852|Vega:OTTMUSG00000045393 +100042875 Gm12059 MGI:MGI:3649372 +100042880 Rpl17-ps10 MGI:MGI:3642871|Ensembl:ENSMUSG00000081895 +100042881 Gm10352 MGI:MGI:3708825|Ensembl:ENSMUSG00000091987|Vega:OTTMUSG00000045395 +100042886 Gm13806 MGI:MGI:3651556 +100042889 C920021L13Rik MGI:MGI:1923991|Ensembl:ENSMUSG00000080727 +100042891 Vmn2r47 MGI:MGI:3757929|Ensembl:ENSMUSG00000094107|Vega:OTTMUSG00000038502 +100042894 Vmn2r46 MGI:MGI:3757899|Ensembl:ENSMUSG00000090342|Vega:OTTMUSG00000038501 +100042898 Gm4097 MGI:MGI:3782273 +100042899 Gm4098 MGI:MGI:3782274 +100042900 Gm10540 MGI:MGI:3642696 +100042903 Gm4101 MGI:MGI:3782277 +100042904 Gm15318 MGI:MGI:3705106 +100042907 Gm13811 MGI:MGI:3649415 +100042912 Gm10489 MGI:MGI:3704505 +100042914 Gm4105 MGI:MGI:3782281 +100042915 Gm4106 MGI:MGI:3782282 +100042916 Gm4107 MGI:MGI:3782283 +100042918 Uqcrh-ps1 MGI:MGI:3641869 +100042921 Vmn2r51 MGI:MGI:3757937|Ensembl:ENSMUSG00000058685|Vega:OTTMUSG00000038508 +100042922 H2al1a MGI:MGI:3714114|Ensembl:ENSMUSG00000100626|Vega:OTTMUSG00000016789 +100042925 Gm4111 MGI:MGI:3782287 +100042926 Gm13546 MGI:MGI:3649666|Ensembl:ENSMUSG00000086862 +100042927 H2al1b MGI:MGI:3650131|Ensembl:ENSMUSG00000101819|Vega:OTTMUSG00000016779 +100042929 H2al1c MGI:MGI:3711280|Ensembl:ENSMUSG00000096097|Vega:OTTMUSG00000016783 +100042931 H2al1d MGI:MGI:3710419|Ensembl:ENSMUSG00000094904|Vega:OTTMUSG00000016781 +100042932 Gm14813 MGI:MGI:3705714 +100042936 Gm4115 MGI:MGI:3782291 +100042937 Gm4116 MGI:MGI:3782292 +100042939 H2al1f MGI:MGI:3649874|Ensembl:ENSMUSG00000095655|Vega:OTTMUSG00000016785 +100042940 Gm4117 MGI:MGI:3782293 +100042941 Gm4118 MGI:MGI:3782294 +100042943 H2al1g MGI:MGI:3710577|Ensembl:ENSMUSG00000095662|Vega:OTTMUSG00000016788 +100042944 H2al1h MGI:MGI:3711282|Ensembl:ENSMUSG00000099443|Vega:OTTMUSG00000016784 +100042945 Gm4120 MGI:MGI:3782296 +100042946 H2al1i MGI:MGI:3710416|Ensembl:ENSMUSG00000095445|Vega:OTTMUSG00000016780 +100042947 Gm14816 MGI:MGI:3705674 +100042948 Gm15760 MGI:MGI:3642834 +100042951 Gm4123 MGI:MGI:3782299 +100042953 Gm4125 MGI:MGI:3782301 +100042957 Gm4128 MGI:MGI:3782304 +100042958 Gm4129 MGI:MGI:3782305 +100042959 Gm4130 MGI:MGI:3782306 +100042960 Gm4131 MGI:MGI:3782307|Ensembl:ENSMUSG00000100486|Vega:OTTMUSG00000045570 +100042961 Gm13877 MGI:MGI:3651488 +100042963 Gm4132 MGI:MGI:3782308 +100042964 Gm4133 MGI:MGI:3782309|Ensembl:ENSMUSG00000095745|Vega:OTTMUSG00000038190 +100042965 Gm13879 MGI:MGI:3649538 +100042966 Vmn1r-ps79 MGI:MGI:2685498 +100042967 Gm4134 MGI:MGI:3782310 +100042968 Vmn1r101 MGI:MGI:3782311|Ensembl:ENSMUSG00000094545|Vega:OTTMUSG00000038194 +100042971 Gm10670 MGI:MGI:3642641|Ensembl:ENSMUSG00000094762|Vega:OTTMUSG00000038195 +100042976 Gm4141 MGI:MGI:3782317|Ensembl:ENSMUSG00000095837|Vega:OTTMUSG00000038199 +100042982 Gm4146 MGI:MGI:3782322 +100042988 Gm4151 MGI:MGI:3782327 +100042989 Gm4152 MGI:MGI:3782328 +100042990 Gm12089 MGI:MGI:3650341 +100042996 Vmn1r114 MGI:MGI:3642588|Ensembl:ENSMUSG00000094085|Vega:OTTMUSG00000038149 +100042997 Gm4157 MGI:MGI:3782333 +100043000 Rpl3-ps1 MGI:MGI:3644217 +100043002 Llph-ps2 MGI:MGI:3642864 +100043006 Vmn1r-ps73 MGI:MGI:3782339 +100043008 Gm4165 MGI:MGI:3782341 +100043010 Rpl10-ps6 MGI:MGI:3782343 +100043013 Vmn1r126 MGI:MGI:3782346|Ensembl:ENSMUSG00000096813|Vega:OTTMUSG00000038163 +100043016 Vmn1r131 MGI:MGI:3782348|Ensembl:ENSMUSG00000093941|Vega:OTTMUSG00000038170 +100043019 Gm4175 MGI:MGI:3782351|Ensembl:ENSMUSG00000096513|Vega:OTTMUSG00000038112 +100043020 Gm11680 MGI:MGI:3650354 +100043022 Gm9774 MGI:MGI:3642386 +100043024 Tnxa MGI:MGI:2148489 +100043025 Gm4177 MGI:MGI:3782353|Ensembl:ENSMUSG00000096760|Vega:OTTMUSG00000038113 +100043026 Vmn1r-ps77 MGI:MGI:3647529 +100043027 Gm11575 MGI:MGI:3649592 +100043028 Gm4178 MGI:MGI:3782354 +100043029 Vmn1r138 MGI:MGI:3782355|Ensembl:ENSMUSG00000095163|Vega:OTTMUSG00000038119 +100043030 Rps27-ps2 MGI:MGI:3782356 +100043031 Gm4181 MGI:MGI:3782357 +100043033 Gm16451 MGI:MGI:3647461|Ensembl:ENSMUSG00000096304|Vega:OTTMUSG00000038121 +100043034 Rex2 MGI:MGI:1328322|Ensembl:ENSMUSG00000067919|Vega:OTTMUSG00000010655 +100043037 Gm10666 MGI:MGI:3704285|Ensembl:ENSMUSG00000096348|Vega:OTTMUSG00000038122 +100043039 Gm4184 MGI:MGI:3782360 +100043040 1110002L01Rik MGI:MGI:1915821|Ensembl:ENSMUSG00000071456 +100043041 Gm4185 MGI:MGI:3782361 +100043042 Zscan4-ps3 MGI:MGI:3708489 +100043043 Gm4187 MGI:MGI:3782363|Ensembl:ENSMUSG00000093871|Vega:OTTMUSG00000038053 +100043045 Gm4189 MGI:MGI:3782365 +100043048 Vmn1r-ps70 MGI:MGI:3782368 +100043049 Gm11582 MGI:MGI:3652084 +100043051 Vmn1r149 MGI:MGI:3782370|Ensembl:ENSMUSG00000094542|Vega:OTTMUSG00000038057 +100043053 Gm10620 MGI:MGI:3708792 +100043057 Tmem207 MGI:MGI:2685386|Ensembl:ENSMUSG00000091972 +100043058 Gm10665 MGI:MGI:3642415|Ensembl:ENSMUSG00000096871|Vega:OTTMUSG00000038058 +100043059 Gm4199 MGI:MGI:3782376 +100043060 Gm4200 MGI:MGI:3782377 +100043061 Gm4201 MGI:MGI:3782378|Ensembl:ENSMUSG00000095984|Vega:OTTMUSG00000038062 +100043063 Gm4203 MGI:MGI:3782380 +100043064 Gm4204 MGI:MGI:3782381 +100043065 6030469F06Rik MGI:MGI:3588235|Ensembl:ENSMUSG00000095953 +100043067 Vmn1r158 MGI:MGI:3646143|Ensembl:ENSMUSG00000094700|Vega:OTTMUSG00000038047 +100043069 Gm4207 MGI:MGI:3809198 +100043070 Gm4208 MGI:MGI:3782384 +100043072 A230070E04Rik MGI:MGI:3603403 +100043074 Gm4211 MGI:MGI:3782387 +100043075 Gm10179 MGI:MGI:3708748 +100043078 Gm13916 MGI:MGI:3651612 +100043079 Gm4214 MGI:MGI:3782390|Ensembl:ENSMUSG00000092297|Vega:OTTMUSG00000038027 +100043080 Gm14859 MGI:MGI:3705727 +100043083 Gm4216 MGI:MGI:3782392|Ensembl:ENSMUSG00000094532|Vega:OTTMUSG00000038028 +100043084 Gm4217 MGI:MGI:3782393 +100043086 Gm16456 MGI:MGI:3647759 +100043087 Gm4219 MGI:MGI:3782395 +100043088 Vmn1r166 MGI:MGI:3782396|Ensembl:ENSMUSG00000096073|Vega:OTTMUSG00000038034 +100043089 Gm4221 MGI:MGI:3782397 +100043090 Gm4222 MGI:MGI:3782398 +100043092 Gm4224 MGI:MGI:3782400|Ensembl:ENSMUSG00000110042 +100043095 Vmn1r-ps84 MGI:MGI:3782403 +100043099 Gm4230 MGI:MGI:3782406 +100043101 Vmn1r168 MGI:MGI:3704286|Ensembl:ENSMUSG00000074291|Vega:OTTMUSG00000038001 +100043102 4632428C04Rik MGI:MGI:1921600|Ensembl:ENSMUSG00000097184 +100043103 Vmn1r169 MGI:MGI:3782408|Ensembl:ENSMUSG00000094602|Vega:OTTMUSG00000038002 +100043105 Gm4234 MGI:MGI:3782410 +100043106 Gm10247 MGI:MGI:3641838 +100043108 Cyp2c69 MGI:MGI:3721049|Ensembl:ENSMUSG00000092008 +100043112 Gm4238 MGI:MGI:3782414 +100043115 Gm4240 MGI:MGI:3782417 +100043119 Gm4241 MGI:MGI:3782418 +100043120 Gm4242 MGI:MGI:3782419 +100043121 Gm10175 MGI:MGI:3704287 +100043123 Cd300ld4 MGI:MGI:3702658|Ensembl:ENSMUSG00000069609|Vega:OTTMUSG00000003605 +100043125 Cd300ld5 MGI:MGI:3702661|Ensembl:ENSMUSG00000089722|Vega:OTTMUSG00000003606 +100043126 Gm4245 MGI:MGI:3782422 +100043127 Gm4246 MGI:MGI:3782423 +100043128 Gm4247 MGI:MGI:3782424 +100043129 Gm4248 MGI:MGI:3782425 +100043132 Gm4251 MGI:MGI:3782428 +100043133 9130023H24Rik MGI:MGI:2442738|Ensembl:ENSMUSG00000062944|Vega:OTTMUSG00000058673 +100043134 Gm4252 MGI:MGI:3782429 +100043140 H2-M10.5-ps1 MGI:MGI:3782433 +100043141 Rpl10a-ps1 MGI:MGI:3705885 +100043142 Gm4257 MGI:MGI:3782434 +100043143 Gm4258 MGI:MGI:3782435 +100043144 Gm4259 MGI:MGI:3782436 +100043147 Gm4262 MGI:MGI:3782439|Ensembl:ENSMUSG00000097056 +100043148 Gm4263 MGI:MGI:3782440 +100043150 Gm4265 MGI:MGI:3782442|Ensembl:ENSMUSG00000108504 +100043151 Gm13204 MGI:MGI:3651444 +100043152 Gm4266 MGI:MGI:3782443 +100043155 Gm4269 MGI:MGI:3782446 +100043156 Gm4270 MGI:MGI:3782447 +100043158 Gm4271 MGI:MGI:3782448 +100043160 Gm10012 MGI:MGI:3642454 +100043162 Gm4274 MGI:MGI:3782451 +100043163 Gm4275 MGI:MGI:3782452 +100043164 Gm4276 MGI:MGI:3782453 +100043166 Gm12517 MGI:MGI:3649535 +100043167 Gm9788 MGI:MGI:3704496 +100043168 Gm14292 MGI:MGI:3649964 +100043169 Gm4278 MGI:MGI:3782455 +100043171 Gm4279 MGI:MGI:3782456 +100043172 Gm10080 MGI:MGI:3710529 +100043173 BB114814 MGI:MGI:2142288 +100043176 Gm15628 MGI:MGI:3783072 +100043177 Trav12d-1 MGI:MGI:3649417|IMGT/GENE-DB:TRAV12D-1 +100043180 Gm28269 MGI:MGI:5578975|Ensembl:ENSMUSG00000101818|Vega:OTTMUSG00000048338 +100043182 Gm14563 MGI:MGI:3705329 +100043184 Gm11703 MGI:MGI:3649808 +100043187 Gm4284 MGI:MGI:3782462 +100043188 Gm10696 MGI:MGI:3702972|Ensembl:ENSMUSG00000074424|Vega:OTTMUSG00000034828 +100043189 Gm4285 MGI:MGI:3782463 +100043191 Gm4287 MGI:MGI:3782465 +100043192 Rpl31-ps14 MGI:MGI:3704189 +100043194 Sult2a2 MGI:MGI:107550|Ensembl:ENSMUSG00000070811|Vega:OTTMUSG00000048115 +100043197 Trav12d-2 MGI:MGI:3642520|IMGT/GENE-DB:TRAV12D-2 +100043199 Gm4290 MGI:MGI:3782467 +100043200 Olfr819 MGI:MGI:3030653|Ensembl:ENSMUSG00000094295|Vega:OTTMUSG00000056636 +100043201 Gm4291 MGI:MGI:3782468 +100043202 Trav3d-3 MGI:MGI:3782469|IMGT/GENE-DB:TRAV3D-3 +100043203 Gm10310 MGI:MGI:3710649 +100043204 Trav14n-1 MGI:MGI:3642439|IMGT/GENE-DB:TRAV14N-1 +100043205 Gm13815 MGI:MGI:3649318 +100043207 Amy2a1 MGI:MGI:104548|Ensembl:ENSMUSG00000070360|Vega:OTTMUSG00000022432 +100043209 Gm4294 MGI:MGI:3782472 +100043213 5330434G04Rik MGI:MGI:1925519|Ensembl:ENSMUSG00000087620 +100043214 Trav14d-2 MGI:MGI:3646138 +100043215 Rpl36-ps3 MGI:MGI:3642480 +100043216 Gm4297 MGI:MGI:3782476|Ensembl:ENSMUSG00000081218|Vega:OTTMUSG00000016994 +100043217 Gm10237 MGI:MGI:3641816 +100043218 Trav12n-1 MGI:MGI:3782477|IMGT/GENE-DB:TRAV12N-1 +100043219 Gm13975 MGI:MGI:3649230 +100043224 Gm4301 MGI:MGI:3782481|Ensembl:ENSMUSG00000094314|Vega:OTTMUSG00000049691 +100043225 Gm16378 MGI:MGI:3646886 +100043227 Gm4302 MGI:MGI:3782482|Ensembl:ENSMUSG00000091101 +100043228 Gm15235 MGI:MGI:3705756 +100043229 Gm10046 MGI:MGI:3797981|Ensembl:ENSMUSG00000109143 +100043231 Gm4303 MGI:MGI:3782483|Ensembl:ENSMUSG00000112931 +100043232 3110099E03Rik MGI:MGI:1925761|Ensembl:ENSMUSG00000085582 +100043235 Gm4305 MGI:MGI:3782485|Ensembl:ENSMUSG00000112856 +100043236 Gm13977 MGI:MGI:3652169 +100043239 Gm4307 MGI:MGI:3782487|Ensembl:ENSMUSG00000096744 +100043240 Gm15583 MGI:MGI:3783031 +100043242 Gm4308 MGI:MGI:3782489 +100043244 Gm4310 MGI:MGI:3782491 +100043245 Gm4311 MGI:MGI:3782492 +100043247 Gm4312 MGI:MGI:3782493|Ensembl:ENSMUSG00000096640|Vega:OTTMUSG00000049693 +100043251 Gm4316 MGI:MGI:3782497 +100043254 Nps MGI:MGI:3642232|Ensembl:ENSMUSG00000073804|Vega:OTTMUSG00000047867 +100043255 Gm4319 MGI:MGI:3782500 +100043256 Gm9847 MGI:MGI:3642840 +100043257 Rbm3-ps MGI:MGI:3642874 +100043259 Gm13793 MGI:MGI:3652243 +100043260 Gm4321 MGI:MGI:3782502 +100043261 Gm4322 MGI:MGI:3782503 +100043263 Gm14880 MGI:MGI:3705564 +100043265 Gm4325 MGI:MGI:3782506 +100043266 Gm10121 MGI:MGI:3708587 +100043269 Rps19-ps1 MGI:MGI:3782508 +100043270 Trav12n-2 MGI:MGI:3644334|IMGT/GENE-DB:TRAV12N-2 +100043272 Inafm2 MGI:MGI:1915354|Ensembl:ENSMUSG00000074918|Vega:OTTMUSG00000015633 +100043274 Trav9n-3 MGI:MGI:3782511|IMGT/GENE-DB:TRAV9N-3 +100043277 6430590A10Rik MGI:MGI:2442852 +100043278 Gm4332 MGI:MGI:3782515 +100043282 Trav3n-3 MGI:MGI:3782518|IMGT/GENE-DB:TRAV3N-3 +100043283 Gm4335 MGI:MGI:3782519 +100043289 Gm15575 MGI:MGI:3783023 +100043292 Gm4340 MGI:MGI:3782524|Ensembl:ENSMUSG00000090854|Vega:OTTMUSG00000042984 +100043295 Gm15500 MGI:MGI:3782947 +100043296 Gm4342 MGI:MGI:3782526 +100043299 Gm10054 MGI:MGI:3708564 +100043300 Esp16 MGI:MGI:3782529|Ensembl:ENSMUSG00000096345|Vega:OTTMUSG00000042891 +100043304 Amd-ps3 MGI:MGI:3704487 +100043305 Gm4349 MGI:MGI:3782533 +100043306 Gm4350 MGI:MGI:3782534 +100043308 Trav14n-3 MGI:MGI:3584039|IMGT/GENE-DB:TRAV14N-3 +100043309 4732414G09Rik MGI:MGI:3045381|Ensembl:ENSMUSG00000086943 +100043312 Hmgb1-ps5 MGI:MGI:3776505 +100043313 Gm4353 MGI:MGI:3782538 +100043314 Tigit MGI:MGI:3642260|Ensembl:ENSMUSG00000071552 +100043315 LOC100043315 Ensembl:ENSMUSG00000100603 +100043316 Gm4354 MGI:MGI:3782539 +100043317 Gm4355 MGI:MGI:3782540 +100043318 Gm4356 MGI:MGI:3782541 +100043322 Trav12-2 MGI:MGI:5293447|IMGT/GENE-DB:TRAV12-2 +100043323 Scgblbl MGI:MGI:3782545 +100043324 Bnip3l-ps MGI:MGI:3642435|Ensembl:ENSMUSG00000073198 +100043326 Scgb2b3 MGI:MGI:3782547|Ensembl:ENSMUSG00000078754|Vega:OTTMUSG00000045680 +100043330 Gm4366 MGI:MGI:3782551 +100043332 Ankrd66 MGI:MGI:1925106|Ensembl:ENSMUSG00000096140 +100043335 Gm4371 MGI:MGI:3782556 +100043337 Gm4373 MGI:MGI:3782558 +100043338 Gm4374 MGI:MGI:3782559 +100043341 Rpl35a-ps3 MGI:MGI:3704473 +100043342 Gm13134 MGI:MGI:3650641 +100043346 Rpl10-ps3 MGI:MGI:3704336 +100043348 Gm10045 MGI:MGI:3642098 +100043349 Gm13882 MGI:MGI:3650052 +100043354 Gm4383 MGI:MGI:3782568 +100043355 Scgb1b10 MGI:MGI:3782569 +100043373 Gm4398 MGI:MGI:3782583 +100043375 Gm14004 MGI:MGI:3651365 +100043376 Scgb1b15 MGI:MGI:3782584 +100043377 Gm16476 MGI:MGI:3643076 +100043380 Gm4402 MGI:MGI:3782587 +100043381 Gm14308 MGI:MGI:3782921|Ensembl:ENSMUSG00000078880|Vega:OTTMUSG00000016254 +100043383 Scgb1b16 MGI:MGI:3809195 +100043385 Gm16494 MGI:MGI:3641930 +100043386 Gm4405 MGI:MGI:3782590 +100043387 Gm14305 MGI:MGI:3709632|Ensembl:ENSMUSG00000078878|Vega:OTTMUSG00000016251 +100043388 Scgb1b17 MGI:MGI:3809666 +100043391 Rpl10-ps1 MGI:MGI:3650909 +100043392 Gm4409 MGI:MGI:3782594 +100043393 Gm4410 MGI:MGI:3782595 +100043394 Gm13954 MGI:MGI:3649858 +100043397 Gm4412 MGI:MGI:3782597 +100043398 Scgb2b22-ps MGI:MGI:3649641 +100043401 Scgb1b22-ps MGI:MGI:3649636 +100043402 Gm4415 MGI:MGI:3782600 +100043403 Gm14410 MGI:MGI:3709158 +100043404 Gm4416 MGI:MGI:3782601 +100043407 Gm4419 MGI:MGI:3782604 +100043410 Gm12778 MGI:MGI:3649899 +100043416 Gm4425 MGI:MGI:3809660|Ensembl:ENSMUSG00000093846 +100043423 Rpl35a-ps4 MGI:MGI:3650995 +100043424 Gm14005 MGI:MGI:3652191 +100043427 Gm13932 MGI:MGI:3650981 +100043429 Gm12335 MGI:MGI:3650727 +100043431 Gm4430 MGI:MGI:3782614 +100043434 Gm4432 MGI:MGI:3782616 +100043447 Gm12337 MGI:MGI:3650615 +100043450 AA387883 MGI:MGI:3035466 +100043456 Gm10681 MGI:MGI:3711284|Ensembl:ENSMUSG00000095388|Vega:OTTMUSG00000054018 +100043459 Gm10241 MGI:MGI:3704461 +100043461 Gm4450 MGI:MGI:3782634|Ensembl:ENSMUSG00000090817|Vega:OTTMUSG00000046371 +100043462 Nutf2-ps1 MGI:MGI:108008|Ensembl:ENSMUSG00000071497 +100043463 Gm14283 MGI:MGI:3650418 +100043464 Gm4451 MGI:MGI:3782635 +100043467 Gm4454 MGI:MGI:3782638 +100043468 Zfp955b MGI:MGI:4834573|Ensembl:ENSMUSG00000096910 +100043471 Hcfc1r1-ps1 MGI:MGI:3782642 +100043472 Gm4459 MGI:MGI:3782643 +100043474 Olfr1564 MGI:MGI:3782645|Ensembl:ENSMUSG00000096169|Vega:OTTMUSG00000059244 +100043475 Gm4462 MGI:MGI:3782646 +100043476 Gm4463 MGI:MGI:3782647 +100043479 Gm4466 MGI:MGI:3782650 +100043481 Gm4468 MGI:MGI:3782652 +100043483 Rpl36-ps2 MGI:MGI:3650081 +100043484 Gm4470 MGI:MGI:3782654 +100043485 Gm4471 MGI:MGI:3782655 +100043488 Gm4473 MGI:MGI:3782657 +100043489 1300002E11Rik MGI:MGI:1919001|Ensembl:ENSMUSG00000097290 +100043490 Gm10355 MGI:MGI:3641762 +100043492 Gm14054 MGI:MGI:3650805 +100043493 Alms1-ps1 MGI:MGI:3646394 +100043494 Gm4476 MGI:MGI:3782660 +100043495 Gm10155 MGI:MGI:3642914 +100043497 Nat8f7 MGI:MGI:3782661|Ensembl:ENSMUSG00000089694|Vega:OTTMUSG00000034542 +100043498 Gm4478 MGI:MGI:3782662 +100043499 Gm4479 MGI:MGI:3782663 +100043500 Gm4480 MGI:MGI:3782664 +100043501 Gm4481 MGI:MGI:3782665 +100043502 Gm4482 MGI:MGI:3782666 +100043506 Gm11191 MGI:MGI:3641971 +100043507 Gng5-ps MGI:MGI:3783217 +100043508 Ptges3-ps MGI:MGI:3704271 +100043509 Gm4486 MGI:MGI:3782671 +100043510 Gm4487 MGI:MGI:3782672 +100043512 Vmn2r-ps32 MGI:MGI:3761513 +100043513 Gm4489 MGI:MGI:3782674|Ensembl:ENSMUSG00000111952 +100043515 Gm4491 MGI:MGI:3782676 +100043523 Gm4498 MGI:MGI:3782683|Ensembl:ENSMUSG00000094757|Vega:OTTMUSG00000038189 +100043525 Gm12571 MGI:MGI:3649675 +100043527 Gm10443 MGI:MGI:3704272 +100043528 Gm4501 MGI:MGI:3782686 +100043534 Gm11686 MGI:MGI:3652311 +100043536 Vmn1r100 MGI:MGI:3704284|Ensembl:ENSMUSG00000096386|Vega:OTTMUSG00000038193 +100043538 Gm16520 MGI:MGI:4360879 +100043541 B630019A10Rik MGI:MGI:2443371 +100043546 Gm15542 MGI:MGI:3782990 +100043547 Gm4510 MGI:MGI:3782695 +100043549 Gm4512 MGI:MGI:3782697 +100043550 Gm4513 MGI:MGI:3782698 +100043560 Gm4518 MGI:MGI:3782703 +100043564 Gm4521 MGI:MGI:3782706 +100043566 Gm10668 MGI:MGI:3642587|Ensembl:ENSMUSG00000095190|Vega:OTTMUSG00000045828 +100043569 Vmn1r112 MGI:MGI:3649076|Ensembl:ENSMUSG00000094284|Vega:OTTMUSG00000038147 +100043570 Gm11196 MGI:MGI:3649463 +100043571 Gm4524 MGI:MGI:3782709 +100043572 Gm4525 MGI:MGI:3782710 +100043574 Gm4526 MGI:MGI:3782711 +100043576 Gm4528 MGI:MGI:3782713 +100043577 Gm4529 MGI:MGI:3782714 +100043580 Gm4532 MGI:MGI:3809207|Ensembl:ENSMUSG00000000486 +100043582 AU016765 MGI:MGI:3034888|Ensembl:ENSMUSG00000073377 +100043585 Gm4535 MGI:MGI:3782719 +100043588 Gm4536 MGI:MGI:3782720 +100043589 Gm10586 MGI:MGI:3708763 +100043590 Smt3h2-ps2 MGI:MGI:1926284 +100043594 Gm4540 MGI:MGI:3782724 +100043595 Gm4541 MGI:MGI:3782725 +100043596 Vmn1r130 MGI:MGI:3782726|Ensembl:ENSMUSG00000094208|Vega:OTTMUSG00000038168 +100043597 Srcap MGI:MGI:2444036|Ensembl:ENSMUSG00000053877|Ensembl:ENSMUSG00000107023|Vega:OTTMUSG00000048247|Vega:OTTMUSG00000055775 +100043600 Gm4544 MGI:MGI:3782728 +100043602 Gm4545 MGI:MGI:3782729 +100043604 Vmn1r132 MGI:MGI:3647009|Ensembl:ENSMUSG00000074322|Vega:OTTMUSG00000038171 +100043606 Arl4aos MGI:MGI:2151103 +100043607 Gm4548 MGI:MGI:3782732 +100043608 Gm4549 MGI:MGI:3782733 +100043609 Gm14207 MGI:MGI:3649550|Ensembl:ENSMUSG00000074912 +100043614 Vmn1r137 MGI:MGI:3782735|Ensembl:ENSMUSG00000095962|Vega:OTTMUSG00000038117 +100043617 Gm4553 MGI:MGI:3782737 +100043618 Gm10120 MGI:MGI:3641745 +100043622 Gm14383 MGI:MGI:3650547 +100043624 Gm4556 MGI:MGI:3782740 +100043625 Gm4557 MGI:MGI:3782741 +100043626 Gm4558 MGI:MGI:3782742 +100043627 Gm4559 MGI:MGI:3782743|Ensembl:ENSMUSG00000056885 +100043629 Gm10013 MGI:MGI:3704303 +100043630 Gm4561 MGI:MGI:3782745 +100043635 Gm13997 MGI:MGI:3723509 +100043636 AI662270 MGI:MGI:2144254|Ensembl:ENSMUSG00000087107 +100043638 Gm4565 MGI:MGI:3782749|Ensembl:ENSMUSG00000109396|Vega:OTTMUSG00000045837 +100043641 Gm12502 MGI:MGI:3650307 +100043643 Gm15503 MGI:MGI:3782950 +100043644 Gm4566 MGI:MGI:3782750 +100043645 Gm4567 MGI:MGI:3809658|Ensembl:ENSMUSG00000095363|Vega:OTTMUSG00000045838 +100043646 Rpl21-ps12 MGI:MGI:3648214 +100043652 Gm14497 MGI:MGI:3705797 +100043657 Gm4573 MGI:MGI:3782756 +100043658 Gm4574 MGI:MGI:3782757 +100043659 Gm4575 MGI:MGI:3782758 +100043663 Gm4577 MGI:MGI:3782760 +100043665 Gm10662 MGI:MGI:3642760|Ensembl:ENSMUSG00000095683|Vega:OTTMUSG00000045840 +100043667 Vmn1r165 MGI:MGI:3782762|Ensembl:ENSMUSG00000095358|Vega:OTTMUSG00000038032 +100043670 Gm4581 MGI:MGI:3782764 +100043674 Rbx1-ps MGI:MGI:3710517 +100043675 Gm10233 MGI:MGI:3704447 +100043676 Gm4583 MGI:MGI:3782766 +100043679 Gm4585 MGI:MGI:3782768 +100043681 Gm14176 MGI:MGI:3650021 +100043682 Gm10584 MGI:MGI:3641800|Ensembl:ENSMUSG00000109270 +100043683 Gm4587 MGI:MGI:3782770 +100043684 Amy2a4 MGI:MGI:3711258|Ensembl:ENSMUSG00000096770|Vega:OTTMUSG00000022433 +100043686 Amy2a3 MGI:MGI:3714985|Ensembl:ENSMUSG00000093931|Vega:OTTMUSG00000022430 +100043688 Amy2a2 MGI:MGI:3711220|Ensembl:ENSMUSG00000096569|Vega:OTTMUSG00000022431 +100043689 Gm11445 MGI:MGI:3651163 +100043692 Gm15531 MGI:MGI:3782979 +100043695 Gm15483 MGI:MGI:3705631 +100043696 Gm11450 MGI:MGI:3651345 +100043697 Gm9959 MGI:MGI:3708636 +100043698 Gm14003 MGI:MGI:3649824 +100043699 Gm4593 MGI:MGI:3782776 +100043702 Gm4596 MGI:MGI:3782779 +100043703 Tpt1-ps3 MGI:MGI:2664997 +100043705 Gm9761 MGI:MGI:3708640 +100043706 Gm4598 MGI:MGI:3782781|Ensembl:ENSMUSG00000108470 +100043707 Gm4599 MGI:MGI:3782782 +100043709 Gm4600 MGI:MGI:3782783 +100043711 Gm4601 MGI:MGI:3782784 +100043712 Gm9844 MGI:MGI:3704288 +100043714 Gm10774 MGI:MGI:3642325 +100043716 Gm4602 MGI:MGI:3782785 +100043718 Gm4604 MGI:MGI:3782787 +100043719 Gm9770 MGI:MGI:3708545 +100043720 Gm4605 MGI:MGI:3782788 +100043721 Gm4606 MGI:MGI:3782789 +100043722 Gm4607 MGI:MGI:3782790 +100043724 Gm4609 MGI:MGI:3782792 +100043726 Gm4610 MGI:MGI:3782793 +100043728 LOC100043728 - +100043729 Gm14010 MGI:MGI:3649271 +100043730 Gm14008 MGI:MGI:3651416 +100043731 Rpl27a-ps3 MGI:MGI:3782795 +100043732 Gm4613 MGI:MGI:3782796 +100043734 Gm16409 MGI:MGI:3646708 +100043735 Gm14028 MGI:MGI:3650448 +100043740 Gm4617 MGI:MGI:3704225 +100043742 Gm15403 MGI:MGI:3641944 +100043752 Rps2-ps6 MGI:MGI:3644876 +100043755 Gm10132 MGI:MGI:3704449 +100043757 Zfp831 MGI:MGI:3641861|Ensembl:ENSMUSG00000050600|Vega:OTTMUSG00000017459 +100043759 Gm14335 MGI:MGI:3801741 +100043761 Gm14399 MGI:MGI:3650082 +100043762 Gm14442 MGI:MGI:3652323 +100043763 Gm14438 MGI:MGI:3652091 +100043764 Gm4631 MGI:MGI:3782813 +100043765 Gm4632 MGI:MGI:3782814 +100043766 Gm14057 MGI:MGI:3705433 +100043767 Gm4633 MGI:MGI:3782815 +100043768 Gm14049 MGI:MGI:3650777 +100043770 Gm4635 MGI:MGI:3782817 +100043771 Gm10651 MGI:MGI:3704290 +100043772 Zfp850 MGI:MGI:3036281|Ensembl:ENSMUSG00000096916|Vega:OTTMUSG00000042768 +100043777 Gm4640 MGI:MGI:3782822 +100043780 Rps3a2 MGI:MGI:3642853 +100043782 Gm4644 MGI:MGI:3782826 +100043785 Gm14094 MGI:MGI:3651963 +100043787 Rpl36a-ps1 MGI:MGI:3642585 +100043788 Gm14211 MGI:MGI:3652008 +100043792 Gm14066 MGI:MGI:3649728 +100043793 Gm4651 MGI:MGI:3782833 +100043796 Gm10169 MGI:MGI:3642393 +100043797 Gm4654 MGI:MGI:3782836 +100043799 Rps13-ps6 MGI:MGI:3650996 +100043801 Gm4657 MGI:MGI:3782839 +100043803 Orai2-ps MGI:MGI:3782841 +100043804 Gm4660 MGI:MGI:3782842 +100043805 Gm10224 MGI:MGI:3642708 +100043806 Gm9816 MGI:MGI:3704465 +100043809 Frg2f11 MGI:MGI:3782845 +100043811 Frg2f12 MGI:MGI:3782846 +100043812 Gm4665 MGI:MGI:3782847 +100043813 Rps27rt MGI:MGI:3704345|Ensembl:ENSMUSG00000050621|Vega:OTTMUSG00000049223 +100043814 Frg2f13 MGI:MGI:3805017 +100043817 Gm4668 MGI:MGI:3782849 +100043818 Gm4669 MGI:MGI:3782850 +100043820 9030622O22Rik MGI:MGI:1918820 +100043823 Gm4673 MGI:MGI:3782854 +100043824 Gm4674 MGI:MGI:3782855 +100043825 Gm4675 MGI:MGI:3782856 +100043826 Mrps36-ps1 MGI:MGI:3809201 +100043827 Scgb2b1 MGI:MGI:3782857 +100043828 Gm4678 MGI:MGI:3782858 +100043831 Gm4681 MGI:MGI:3782861 +100043832 Gm14122 MGI:MGI:3651998 +100043836 Scgb2b7 MGI:MGI:3782864|Ensembl:ENSMUSG00000094053|Vega:OTTMUSG00000045708 +100043839 Gm14148 MGI:MGI:3651554 +100043840 Gm14150 MGI:MGI:3651006 +100043842 Scgb2b11 MGI:MGI:3782867|Ensembl:ENSMUSG00000099729|Vega:OTTMUSG00000045758 +100043843 Rps15a-ps7 MGI:MGI:3650538 +100043853 Gm4691 MGI:MGI:3782871 +100043856 Scgb2b18 MGI:MGI:3782872|Ensembl:ENSMUSG00000100058|Vega:OTTMUSG00000045803 +100043859 Scgb1b21 MGI:MGI:3782875 +100043860 Scgb1b24 MGI:MGI:3649643|Ensembl:ENSMUSG00000078753|Vega:OTTMUSG00000008385 +100043861 Klrb1 MGI:MGI:96877|Ensembl:ENSMUSG00000079299|Vega:OTTMUSG00000056393 +100043864 Scgb1b26-ps MGI:MGI:3649711 +100043865 Gm12755 MGI:MGI:3649708 +100043866 Gm12760 MGI:MGI:3649974 +100043868 Scgb1b30 MGI:MGI:3649901|Ensembl:ENSMUSG00000078752|Vega:OTTMUSG00000008394 +100043869 Gm14494 MGI:MGI:3704210 +100043871 Gm4701 MGI:MGI:3782881 +100043872 Rpl17-ps9 MGI:MGI:3641818 +100043876 Gm4705 MGI:MGI:3782885 +100043879 Gm4707 MGI:MGI:3782887 +100043880 Gm14248 MGI:MGI:3651255 +100043882 Gm14277 MGI:MGI:3650350 +100043883 Gm4708 MGI:MGI:3782888 +100043885 Gm4710 MGI:MGI:3782890 +100043886 Gm16391 MGI:MGI:3645390 +100043887 Gm4711 MGI:MGI:3782891 +100043890 Dynlt1-ps1 MGI:MGI:3642625 +100043892 Gm14222 MGI:MGI:3651737 +100043893 Rpl36a-ps3 MGI:MGI:3642503 +100043894 Gm4714 MGI:MGI:3782894 +100043896 Gm14246 MGI:MGI:3651253 +100043899 R3hdml MGI:MGI:3650937|Ensembl:ENSMUSG00000078949|Vega:OTTMUSG00000001070 +100043902 Six3os1 MGI:MGI:1925118|Ensembl:ENSMUSG00000093460 +100043903 Gm4718 MGI:MGI:3782898 +100043904 Gm4719 MGI:MGI:3782899 +100043906 Gm10184 MGI:MGI:3704480 +100043908 Gm14237 MGI:MGI:3651677 +100043909 Gm4721 MGI:MGI:3782901 +100043910 A630075F10Rik MGI:MGI:3604957|Ensembl:ENSMUSG00000097065 +100043911 Ppp4r1l-ps MGI:MGI:1924560|Ensembl:ENSMUSG00000055897 +100043914 Zfp968 MGI:MGI:3782903|Ensembl:ENSMUSG00000078898|Vega:OTTMUSG00000016226 +100043915 Gm4724 MGI:MGI:3782904|Ensembl:ENSMUSG00000078897|Vega:OTTMUSG00000016225 +100043918 LOC100043918 - +100043920 Fam205a4 MGI:MGI:5434294|Ensembl:ENSMUSG00000078746|Vega:OTTMUSG00000011339 +100043921 LOC100043921 - +100043931 LOC100043931 - +100043932 Gm14352 MGI:MGI:3650961 +100043933 Gm4725 MGI:MGI:3782905 +100043934 Gm4726 MGI:MGI:3782906 +100043935 Gm14365 MGI:MGI:3650556 +100043938 Gm14720 MGI:MGI:3705282 +100043940 Gm14509 MGI:MGI:3705422 +100043942 Gm14503 MGI:MGI:3705694 +100043943 Gm14864 MGI:MGI:3705681 +100043944 Gm16480 MGI:MGI:3648372 +100043945 Gm14491 MGI:MGI:3705582 +100043946 Gm14635 MGI:MGI:3705138|Ensembl:ENSMUSG00000087591 +100043949 Gm14520 MGI:MGI:3705430 +100043950 Gm14516 MGI:MGI:3705695 +100043951 Gm4730 MGI:MGI:3782910 +100043953 Gm14885 MGI:MGI:3705619 +100043954 Gm14529 MGI:MGI:3642255 +100043955 Gm15028 MGI:MGI:3705685 +100043956 Gm14561 MGI:MGI:3705344 +100043957 Gm4732 MGI:MGI:3782912 +100043989 Vh7183.a34psi.56 - +100044068 LOC100044068 - +100044082 LOC100044082 - +100044193 Gm20939 MGI:MGI:5434295|Ensembl:ENSMUSG00000095193 +100044236 Copg2os2 MGI:MGI:1858731 +100044319 LOC100044319 - +100044381 Znf729 - +100044404 Gm17763 MGI:MGI:5009927 +100044509 Tgfbr3l MGI:MGI:3833469|Ensembl:ENSMUSG00000089736|Vega:OTTMUSG00000016477 +100044526 Gm17764 MGI:MGI:5009928 +100044627 LOC100044627 - +100044633 LOC100044633 - +100044666 Rps10-ps4 MGI:MGI:3783077 +100044740 LOC100044740 - +100044748 Gm17766 MGI:MGI:5009930 +100044855 Gm16042 MGI:MGI:3801935 +100044983 Gm20940 MGI:MGI:5434296 +100045026 LOC100045026 - +100045066 Gm17767 MGI:MGI:5009931 +100045125 Gm17768 MGI:MGI:5009932 +100045211 Gm16082 MGI:MGI:3802036 +100045332 LOC100045332 - +100045396 Gm9908 MGI:MGI:3708779 +100045469 Gm14204 MGI:MGI:3651576|Ensembl:ENSMUSG00000086496 +100045653 Gm17769 MGI:MGI:5009933 +100045676 Gm15031 MGI:MGI:3641804 +100045766 Gm10126 MGI:MGI:3809072 +100045778 Rnf223 MGI:MGI:3588193|Ensembl:ENSMUSG00000110404|Vega:OTTMUSG00000033635 +100045792 Ect2l MGI:MGI:3641723|Ensembl:ENSMUSG00000071392|Vega:OTTMUSG00000059704 +100046034 Gm14279 MGI:MGI:3650107 +100046078 Gm15266 MGI:MGI:3705867 +100046082 Gm12012 MGI:MGI:3651575 +100046095 Gm17771 MGI:MGI:5009935 +100046119 Mcg1038069 - +100046282 Gm20563 MGI:MGI:5295670 +100046290 Gm13370 MGI:MGI:3651012 +100046296 Gm20941 MGI:MGI:5434297 +100046305 Gm17772 MGI:MGI:5009936 +100046535 LOC100046535 - +100046572 Gm14712 MGI:MGI:3705389 +100046579 Gm10074 MGI:MGI:3708632 +100046591 Gm17775 MGI:MGI:5009939 +100046638 Gm13338 MGI:MGI:3651856 +100046692 Gm20564 MGI:MGI:5295671 +100046707 Gm17777 MGI:MGI:5009941 +100046796 Gm14567 MGI:MGI:3705732 +100046950 Gm17778 MGI:MGI:5009942 +100046961 Gm17779 MGI:MGI:5009943 +100047000 Gm13005 MGI:MGI:3650102 +100047044 LOC100047044 - +100047050 Gm20566 MGI:MGI:5295673 +100047086 Nalp1b - +100047092 Gm20567 MGI:MGI:5295674 +100047123 Gm15743 MGI:MGI:3783185 +100047133 Gm16894 MGI:MGI:4439818|Ensembl:ENSMUSG00000097899 +100047282 Gm20568 MGI:MGI:5295675 +100047372 LOC100047372 - +100047482 Pitpnm2os2 MGI:MGI:3840147 +100047501 LOC100047501 - +100047529 Gm17780 MGI:MGI:5009944 +100047554 Gm17781 MGI:MGI:5009945 +100047646 Gm17782 MGI:MGI:5009946 +100047671 Gm17783 MGI:MGI:5009947 +100047966 Gm15725 MGI:MGI:3833682 +100048007 Gm20942 MGI:MGI:5434298 +100048019 Gm16958 MGI:MGI:4439882 +100048057 Gm9830 MGI:MGI:3704332 +100048142 Gm20570 MGI:MGI:5295677 +100048185 Gm29692 MGI:MGI:5588851 +100048204 Gm17786 MGI:MGI:5009950 +100048312 Gm17788 MGI:MGI:5009952 +100048427 Gm13875 MGI:MGI:3649350 +100048452 LOC100048452 - +100048534 Cfap43 MGI:MGI:1289258|Ensembl:ENSMUSG00000044948|Vega:OTTMUSG00000034162 +100048620 LOC100048620 - +100048644 Pet117 MGI:MGI:5295678|Ensembl:ENSMUSG00000098387|Vega:OTTMUSG00000044913 +100048658 Ddx43 MGI:MGI:3642857|Ensembl:ENSMUSG00000070291|Vega:OTTMUSG00000019690 +100048701 AI847159 MGI:MGI:3528181|Ensembl:ENSMUSG00000084826 +100048798 LOC100048798 - +100048813 LOC100048813 - +100048823 LOC100048823 - +100048884 Mup18 MGI:MGI:3705220|Ensembl:ENSMUSG00000078674|Vega:OTTMUSG00000007486 +100048885 Gm2083 - +100048894 Gm10680 MGI:MGI:3704335 +100048895 9330020H09Rik MGI:MGI:3704457 +100048896 F630040L22Rik MGI:MGI:3704344 +100048897 4731419I09Rik MGI:MGI:3704222 +100048898 Gm10751 MGI:MGI:3704504 +100048901 G630022F23Rik MGI:MGI:3704248 +100048911 D930003E18Rik MGI:MGI:3697423 +100048916 4930474H06Rik MGI:MGI:3697432 +100048917 B930036N10Rik MGI:MGI:3702496 +100048926 Gm12945 MGI:MGI:3704237 +100048941 Gm3203 MGI:MGI:3781382 +100048966 Gofm1 MGI:MGI:3707013 +100048967 Gofm2 MGI:MGI:3707014 +100048968 Gofm3 MGI:MGI:3707015 +100048969 Gofm4 MGI:MGI:3707016 +100048970 Wtmq3 MGI:MGI:3707045 +100048971 Wtmq4 MGI:MGI:3707046 +100048972 Wtmq7 MGI:MGI:3707049 +100048973 Wtmq8 MGI:MGI:3707050 +100048974 Hbtq MGI:MGI:3707208 +100048975 Wtmq5 MGI:MGI:3707047 +100048976 Wtmq1 MGI:MGI:3707043 +100048977 Wtmq6 MGI:MGI:3707048 +100048978 Wtmq9 MGI:MGI:3707051 +100048979 Wtmq2 MGI:MGI:3707044 +100048981 Gm14343 MGI:MGI:3701948 +100048982 Gm13558 MGI:MGI:3702047 +100048983 Gm14453 MGI:MGI:3702165 +100048984 Gm13764 MGI:MGI:3702117 +100048985 Gm14321 MGI:MGI:3701951 +100048997 AW743351 MGI:MGI:2687288 +100049077 Gm45914 MGI:MGI:5825551 +100049079 Find1 MGI:MGI:1891120 +100049080 Fina1 MGI:MGI:3707782 +100049081 Bwt1 MGI:MGI:3707783 +100049083 Find2 MGI:MGI:1891121 +100049155 D930027P08Rik MGI:MGI:3704500 +100049156 BC057193 MGI:MGI:3642413 +100049161 Gm13032 MGI:MGI:3702685|Ensembl:ENSMUSG00000085918 +100049162 BC001981 MGI:MGI:3704411 +100049163 Gm9777 MGI:MGI:3642248 +100049164 B130046B21Rik MGI:MGI:3704458 +100049165 Gm9857 MGI:MGI:3704224 +100049166 Gm16499 MGI:MGI:3704267 +100049167 Gm10550 MGI:MGI:3704193 +100049168 Gm10392 MGI:MGI:3704377 +100049170 4632427I20Rik MGI:MGI:3704448 +100049172 Gm10428 MGI:MGI:3704375 +100049540 Gm4734 MGI:MGI:3782914 +100049545 Mir741 MGI:MGI:3709839|Ensembl:ENSMUSG00000077119|miRBase:MI0005205 +100049546 Mir743 MGI:MGI:3709841|Ensembl:ENSMUSG00000077127|miRBase:MI0005207 +100049547 Mir804 MGI:MGI:3709842|Ensembl:ENSMUSG00000076450|miRBase:MI0005203 +100049548 Mir742 MGI:MGI:3709840|Ensembl:ENSMUSG00000077092|miRBase:MI0005206 +100049549 Mir181d MGI:MGI:3709847|Ensembl:ENSMUSG00000076338|miRBase:MI0005450 +100049552 Gm10199 MGI:MGI:3704498 +100049553 Idd6.2 MGI:MGI:3709972 +100049554 Idd6.1 MGI:MGI:3709971 +100049555 Idd6.3 MGI:MGI:3709973 +100049562 Gm10176 MGI:MGI:3704199 +100049565 B230207O21Rik MGI:MGI:3704213 +100049566 Gm10545 MGI:MGI:3704485 +100049568 Gm10252 MGI:MGI:3704292 +100049569 A730015C16Rik MGI:MGI:3704235 +100049570 Gm10627 MGI:MGI:3704321 +100049584 Sbmd5 MGI:MGI:3628456 +100049589 Fmtq2 MGI:MGI:3710774 +100049590 Fmtq5 MGI:MGI:3710777 +100049591 Fmtq6 MGI:MGI:3710778 +100049592 Fmtq9 MGI:MGI:3710781 +100049593 Fmtq11 MGI:MGI:3710783 +100049594 Fmtq12 MGI:MGI:3710784 +100049595 Fmtq14 MGI:MGI:3710786 +100049596 Fmtq15 MGI:MGI:3710787 +100049597 Fmtq16 MGI:MGI:3710788 +100049598 Fmtq17 MGI:MGI:3710789 +100049599 Fmtq18 MGI:MGI:3710790 +100049600 Fmtq19 MGI:MGI:3710791 +100049601 Fmtq21 MGI:MGI:3710793 +100049602 Fmtq3 MGI:MGI:3710775 +100049603 Vms1 MGI:MGI:3710941 +100049604 Vms2 MGI:MGI:3710942 +100049605 Fmtq1 MGI:MGI:3710773 +100049606 Fmtq4 MGI:MGI:3710776 +100049607 Fmtq8 MGI:MGI:3710780 +100049608 Fmtq10 MGI:MGI:3710782 +100049609 Fmtq13 MGI:MGI:3710785 +100049610 Fmtq20 MGI:MGI:3710792 +100049611 Fmtq7 MGI:MGI:3710779 +100049612 Vms3 MGI:MGI:3710943 +100049710 Mir290a MGI:MGI:3711323|Ensembl:ENSMUSG00000077815|miRBase:MI0000388 +100049711 Mir292 MGI:MGI:3711325|Ensembl:ENSMUSG00000078041|miRBase:MI0000390 +100049712 Mir294 MGI:MGI:3711327|Ensembl:ENSMUSG00000077903|miRBase:MI0000392 +100049713 Mir295 MGI:MGI:3711328|Ensembl:ENSMUSG00000077886|miRBase:MI0000393 +100049714 Mir293 MGI:MGI:3711326|Ensembl:ENSMUSG00000078035|miRBase:MI0000391 +100049715 Mir291a MGI:MGI:3711324|Ensembl:ENSMUSG00000078008|miRBase:MI0000389 +100049789 Gm12264 MGI:MGI:3702404 +100073351 Yy2 MGI:MGI:3837947|Ensembl:ENSMUSG00000046873|Ensembl:ENSMUSG00000091736|Vega:OTTMUSG00000036478 +100093627 D430039P05Rik MGI:MGI:3712003 +100093629 Gm10861 MGI:MGI:3708599 +100093634 Trnaf-aaa - +100093635 Trnaf-gaa - +100093636 Trnal-uaa - +100093637 Trnal-caa - +100093638 Trnal-aag - +100093639 Trnal-gag - +100093640 Trnal-uag - +100093641 Trnal-cag - +100093642 Trnai-aau - +100093643 Trnai-gau - +100093644 Trnai-uau - +100093645 Trnam-cau - +100093646 Trnav-aac - +100093647 Trnav-gac - +100093648 Trnav-uac - +100093649 Trnav-cac - +100093650 Trnas-aga - +100093651 Trnas-gga - +100093652 Trnas-uga - +100093653 Trnas-cga - +100093654 Trnap-agg - +100093655 Trnap-ggg - +100093656 Trnap-ugg - +100093657 Trnap-cgg - +100093658 Trnat-agu - +100093659 Trnat-ggu - +100093660 Trnat-ugu - +100093661 Trnat-cgu - +100093662 Trnaa-agc - +100093663 Trnaa-ggc - +100093664 Trnaa-ugc - +100093665 Trnaa-cgc - +100093666 Trnay-aua - +100093667 Trnay-gua - +100093668 Trnah-aug - +100093669 Trnah-gug - +100093671 Trnaq-cug - +100093672 Trnan-auu - +100093673 Trnan-guu - +100093674 Trnak-uuu - +100093675 Trnak-cuu - +100093676 Trnad-auc - +100093677 Trnad-guc - +100093678 Trnae-uuc - +100093679 Trnae-cuc - +100093680 Trnac-aca - +100093681 Trnac-gca - +100093682 Trnaw-cca - +100093683 Trnar-acg - +100093684 Trnar-ccg - +100093685 Trnar-ucg - +100093686 Trnar-gcg - +100093687 Trnar-ucu - +100093688 Trnar-ccu - +100093689 Trnas-acu - +100093690 Trnas-gcu - +100093691 Trnag-acc - +100093692 Trnag-gcc - +100093693 Trnag-ucc - +100093694 Trnag-ccc - +100093695 Trnastop-uca - +100093696 Trnastop-cua - +100093697 Trnastop-uua - +100093699 Gm10210 MGI:MGI:3708746 +100093700 Gm10400 MGI:MGI:3708745|Ensembl:ENSMUSG00000107456 +100093714 Gm12296 MGI:MGI:3711946 +100093715 Gm10404 MGI:MGI:3708591 +100101046 D230018H15Rik MGI:MGI:3712494 +100101408 Irav1 MGI:MGI:3713726 +100101409 Pbwg1.2 MGI:MGI:3713737 +100101410 Pbwg1.4 MGI:MGI:3713739 +100101411 Pbwg1.5 MGI:MGI:3713742 +100101412 Pbwg1.6 MGI:MGI:3713743 +100101413 Pbwg1.8 MGI:MGI:3713745 +100101414 Mpaps1 MGI:MGI:3713346 +100101415 Pbwg1.3 MGI:MGI:3713738 +100101416 Tilss3 MGI:MGI:3713351 +100101417 Pbwg1.1 MGI:MGI:3713736 +100101418 Pbwg1.7 MGI:MGI:3713744 +100101419 Pbwg1.9 MGI:MGI:3713746 +100101427 Gm9911 MGI:MGI:3708772 +100101428 Cia35 MGI:MGI:3582976 +100101429 Cia37 MGI:MGI:3582981 +100101430 Cia41 MGI:MGI:3583890 +100101431 Char9 MGI:MGI:3713915 +100101432 Cia34 MGI:MGI:3582979 +100101433 Cia42 MGI:MGI:3583891 +100101434 Cia38 MGI:MGI:3583262 +100101435 Cia36 MGI:MGI:3582980 +100101457 A830035O19Rik MGI:MGI:3704334|Ensembl:ENSMUSG00000111329 +100101482 Hrdg1 MGI:MGI:3714795 +100101484 Trac MGI:MGI:4439838|IMGT/GENE-DB:TRAC +100101486 Trav10d MGI:MGI:5293417|IMGT/GENE-DB:TRAV10D +100101488 Trav5d-2 MGI:MGI:5009954|IMGT/GENE-DB:TRAV5D-2 +100101489 Trav5d-3 MGI:MGI:4936976|IMGT/GENE-DB:TRAV5D-3 +100101491 Trav15d-2-dv6d-2 MGI:MGI:3800299|IMGT/GENE-DB:TRAV15D-2/DV6D-2 +100101630 Moen2 MGI:MGI:3715501 +100101631 Suprmam1 MGI:MGI:3715515 +100101632 9530067D14Rik MGI:MGI:3715730 +100101633 Bwq8 MGI:MGI:3715735 +100101634 Moen3 MGI:MGI:3715502 +100101635 Moen1 MGI:MGI:3715500 +100101806 Srp54c MGI:MGI:3714359|Ensembl:ENSMUSG00000079108 +100101807 1700047I17Rik2 MGI:MGI:3714351|Ensembl:ENSMUSG00000094103 +100101919 Dnah7c MGI:MGI:3639762|Ensembl:ENSMUSG00000101337|Vega:OTTMUSG00000046664 +100101934 Trav15d-3 MGI:MGI:5009955|IMGT/GENE-DB:TRAV15D-3 +100101936 Trav12-4 MGI:MGI:5009956|IMGT/GENE-DB:TRAV12-4 +100101939 Trav20 MGI:MGI:3702156|IMGT/GENE-DB:TRAV20 +100101940 Trav21-dv12 MGI:MGI:3652097|IMGT/GENE-DB:TRAV21/DV12 +100101941 Trav22 MGI:MGI:5009957|IMGT/GENE-DB:TRAV22 +100101942 Trdv2-1 MGI:MGI:3642826|IMGT/GENE-DB:TRDV2-1 +100113364 Snora15 MGI:MGI:3819490|Ensembl:ENSMUSG00000093413 +100113365 Nlgn4l MGI:MGI:3775191 +100113367 Lctlp2 MGI:MGI:3582971 +100113368 Rosq1 MGI:MGI:3716479 +100113369 Afteq1 MGI:MGI:3716506 +100113370 Lctlp1 MGI:MGI:3582970 +100113371 Ciaaq1 MGI:MGI:3716480 +100113372 Afteq2 MGI:MGI:3716507 +100113394 Astx5 MGI:MGI:3705133 +100113395 LOC100113395 - +100113396 Gm10689 MGI:MGI:3642613 +100113398 Adat3 MGI:MGI:1924344|Ensembl:ENSMUSG00000035370|Ensembl:ENSMUSG00000113640 +100113411 Trav15-3 MGI:MGI:5009958|IMGT/GENE-DB:TRAV15-3 +100113412 Trav13-4-dv7 MGI:MGI:3702151|IMGT/GENE-DB:TRAV13-4/DV7 +100113413 Trav6-7-dv9 MGI:MGI:3702143|IMGT/GENE-DB:TRAV6-7/DV9 +100113414 Trav4-4-dv10 MGI:MGI:3702138|IMGT/GENE-DB:TRAV4-4/DV10 +100113415 Frct1 MGI:MGI:3717199 +100113416 Frct2 MGI:MGI:3717200 +100113417 Frct3 MGI:MGI:3717201 +100113418 Frct4 MGI:MGI:3717206 +100113419 Radsvq1 MGI:MGI:3717168 +100113420 Frct5 MGI:MGI:3717207 +100113449 Brml8 MGI:MGI:3717811 +100113450 Brml9 MGI:MGI:3717812 +100113451 Brml10 MGI:MGI:3717813 +100113452 Brml13 MGI:MGI:3717814 +100113453 Brml14 MGI:MGI:3717817 +100113454 Secia1 MGI:MGI:3717841 +100113455 Secia3 MGI:MGI:3717843 +100113456 Secia4 MGI:MGI:3717844 +100113457 Secia7 MGI:MGI:3717847 +100113458 Secia8 MGI:MGI:3717848 +100113459 Brml12 MGI:MGI:3717816 +100113460 Secia6 MGI:MGI:3717846 +100113461 Brml11 MGI:MGI:3717815 +100113462 Secia2 MGI:MGI:3717842 +100113463 Secia5 MGI:MGI:3717845 +100113464 Ewrq1 MGI:MGI:3717807 +100113481 Trav23 MGI:MGI:5009959|IMGT/GENE-DB:TRAV23 +100114900 Trdv3 MGI:MGI:5009960|IMGT/GENE-DB:TRDV3 +100114901 Trdv4 MGI:MGI:4887419|IMGT/GENE-DB:TRDV4 +100114902 Trdd1 MGI:MGI:4439547|IMGT/GENE-DB:TRDD1 +100114904 Trdd2 MGI:MGI:4439546|IMGT/GENE-DB:TRDD2 +100115376 Trdj1 MGI:MGI:4819753|IMGT/GENE-DB:TRDJ1 +100118398 Trdj2 MGI:MGI:4887422|IMGT/GENE-DB:TRDJ2 +100123473 Trdc MGI:MGI:98612|IMGT/GENE-DB:TRDC +100124287 Traj61 MGI:MGI:4936997|IMGT/GENE-DB:TRAJ61 +100124288 Traj60 MGI:MGI:4937168|IMGT/GENE-DB:TRAJ60 +100124293 Traj59 MGI:MGI:4439694|IMGT/GENE-DB:TRAJ59 +100124294 Traj58 MGI:MGI:4439695|IMGT/GENE-DB:TRAJ58 +100124295 Traj57 MGI:MGI:4439692|IMGT/GENE-DB:TRAJ57 +100124296 Traj56 MGI:MGI:4439693|IMGT/GENE-DB:TRAJ56 +100124297 Traj55 MGI:MGI:4937105|IMGT/GENE-DB:TRAJ55 +100124333 Traj54 MGI:MGI:4937113|IMGT/GENE-DB:TRAJ54 +100124335 Traj53 MGI:MGI:4439696|IMGT/GENE-DB:TRAJ53 +100124336 Traj52 MGI:MGI:4439697|IMGT/GENE-DB:TRAJ52 +100124337 Traj51 MGI:MGI:4439848|IMGT/GENE-DB:TRAJ51 +100124338 Traj50 MGI:MGI:4440517|IMGT/GENE-DB:TRAJ50 +100124339 Traj49 MGI:MGI:4440527|IMGT/GENE-DB:TRAJ49 +100124340 Traj48 MGI:MGI:4439847|IMGT/GENE-DB:TRAJ48 +100124341 Traj47 MGI:MGI:5009961|IMGT/GENE-DB:TRAJ47 +100124342 Traj46 MGI:MGI:4439852|IMGT/GENE-DB:TRAJ46 +100124343 Traj45 MGI:MGI:4439851|IMGT/GENE-DB:TRAJ45 +100124344 Traj44 MGI:MGI:4439850|IMGT/GENE-DB:TRAJ44 +100124345 Traj43 MGI:MGI:4439849|IMGT/GENE-DB:TRAJ43 +100124346 Traj42 MGI:MGI:4439846|IMGT/GENE-DB:TRAJ42 +100124347 Traj41 MGI:MGI:4439845|IMGT/GENE-DB:TRAJ41 +100124348 Traj40 MGI:MGI:4439592|IMGT/GENE-DB:TRAJ40 +100124349 Traj39 MGI:MGI:4439593|IMGT/GENE-DB:TRAJ39 +100124351 Traj38 MGI:MGI:4439594|IMGT/GENE-DB:TRAJ38 +100124352 Traj37 MGI:MGI:4439595|IMGT/GENE-DB:TRAJ37 +100124353 Traj36 MGI:MGI:4937244|IMGT/GENE-DB:TRAJ36 +100124354 Traj35 MGI:MGI:4439588|IMGT/GENE-DB:TRAJ35 +100124355 Traj34 MGI:MGI:4439589|IMGT/GENE-DB:TRAJ34 +100124356 Traj33 MGI:MGI:4439590|IMGT/GENE-DB:TRAJ33 +100124357 Traj32 MGI:MGI:4439591|IMGT/GENE-DB:TRAV32 +100124358 Traj31 MGI:MGI:4440519|IMGT/GENE-DB:TRAJ31 +100124359 Traj30 MGI:MGI:4439596|IMGT/GENE-DB:TRAJ30 +100124360 Traj29 MGI:MGI:4439743|IMGT/GENE-DB:TRAJ29 +100124361 Traj28 MGI:MGI:4439744|IMGT/GENE-DB:TRAJ28 +100124362 Traj27 MGI:MGI:4439741|IMGT/GENE-DB:TRAJ27 +100124363 Traj26 MGI:MGI:4439742|IMGT/GENE-DB:TRAJ26 +100124364 Traj25 MGI:MGI:4439747|IMGT/GENE-DB:TRAJ25 +100124365 Traj24 MGI:MGI:4439748|IMGT/GENE-DB:TRAJ24 +100124366 Traj23 MGI:MGI:4439745|IMGT/GENE-DB:TRAJ23 +100124367 Traj22 MGI:MGI:4439746|IMGT/GENE-DB:TRAJ22 +100124368 Traj21 MGI:MGI:4439739|IMGT/GENE-DB:TRAJ21 +100124369 Traj20 MGI:MGI:4439740|IMGT/GENE-DB:TRAJ20 +100124370 Traj19 MGI:MGI:4439579|IMGT/GENE-DB:TRAJ19 +100124371 Traj18 MGI:MGI:4440521|IMGT/GENE-DB:TRAJ18 +100124372 Traj17 MGI:MGI:4440523|IMGT/GENE-DB:TRAJ17 +100124387 Traj16 MGI:MGI:4439580|IMGT/GENE-DB:TRAJ16 +100124388 Traj15 MGI:MGI:4439582|IMGT/GENE-DB:TRAJ15 +100124389 Traj14 MGI:MGI:4439581|IMGT/GENE-DB:TRAJ14 +100124390 Traj13 MGI:MGI:4439584|IMGT/GENE-DB:TRAJ13 +100124391 Traj12 MGI:MGI:4439583|IMGT/GENE-DB:TRAJ12 +100124392 Traj11 MGI:MGI:4439578|IMGT/GENE-DB:TRAJ11 +100124393 Traj9 MGI:MGI:4439577|IMGT/GENE-DB:TRAJ9 +100124395 Traj8 MGI:MGI:4439842|IMGT/GENE-DB:TRAJ8 +100124396 Traj7 MGI:MGI:4439843|IMGT/GENE-DB:TRAJ7 +100124397 Traj6 MGI:MGI:4439844|IMGT/GENE-DB:TRAJ6 +100124398 Traj4 MGI:MGI:4439839|IMGT/GENE-DB:TRAJ4 +100124399 Traj3 MGI:MGI:4439840|IMGT/GENE-DB:TRAJ3 +100124400 Traj1 MGI:MGI:4439841|IMGT/GENE-DB:TRAJ1 +100124416 Eeq2 MGI:MGI:3718661 +100124417 Eeq1 MGI:MGI:3718660 +100124431 Mir18b MGI:MGI:3718454|Ensembl:ENSMUSG00000077111|miRBase:MI0005483 +100124432 Mir193b MGI:MGI:3718458|Ensembl:ENSMUSG00000076972|miRBase:MI0005484 +100124433 Mir208b MGI:MGI:3718461|Ensembl:ENSMUSG00000077928|miRBase:MI0005552 +100124435 Mir297a-4 MGI:MGI:3718466|Ensembl:ENSMUSG00000077954|miRBase:MI0005489 +100124437 Mir327 MGI:MGI:3718507|Ensembl:ENSMUSG00000105372|miRBase:MI0005493 +100124438 Mir343 MGI:MGI:3718510|Ensembl:ENSMUSG00000076315|miRBase:MI0005494 +100124439 Mir344-2 MGI:MGI:3718513|Ensembl:ENSMUSG00000093187|miRBase:MI0005495 +100124440 Mir465b-2 MGI:MGI:3718521|Ensembl:ENSMUSG00000096504|miRBase:MI0005499 +100124441 Mir465c-1 MGI:MGI:3718524|Ensembl:ENSMUSG00000095782|miRBase:MI0005500 +100124442 Mir466b-2 MGI:MGI:3718528|Ensembl:ENSMUSG00000076966|miRBase:MI0005503 +100124443 Mir466c-1 MGI:MGI:3718530|Ensembl:ENSMUSG00000104561|miRBase:MI0005505 +100124445 Mir466f-2 MGI:MGI:3718534|Ensembl:ENSMUSG00000077998|miRBase:MI0005508 +100124446 Mir466h MGI:MGI:3718537|Ensembl:ENSMUSG00000077941|miRBase:MI0005511 +100124447 Mir467d MGI:MGI:3718540|Ensembl:ENSMUSG00000077021|miRBase:MI0005513 +100124448 Mir467e MGI:MGI:3718541|Ensembl:ENSMUSG00000076948|miRBase:MI0006128 +100124449 Mir509 MGI:MGI:3718545|Ensembl:ENSMUSG00000106233|miRBase:MI0005516 +100124450 Mir544 MGI:MGI:3718547|Ensembl:ENSMUSG00000077001|miRBase:MI0005555 +100124451 Mir574 MGI:MGI:3718549|Ensembl:ENSMUSG00000077042|miRBase:MI0005518 +100124452 Mir598 MGI:MGI:3718554|Ensembl:ENSMUSG00000076049|miRBase:MI0005556 +100124453 Mir654 MGI:MGI:3718556|Ensembl:ENSMUSG00000077980|miRBase:MI0005520 +100124454 Mir696 MGI:MGI:3718557|miRBase:MI0004677 +100124455 Mir714 MGI:MGI:3718559|miRBase:MI0004699 +100124456 Mir872 MGI:MGI:3718562|Ensembl:ENSMUSG00000077921|miRBase:MI0005549 +100124457 Mir873a MGI:MGI:3718563|Ensembl:ENSMUSG00000078057|miRBase:MI0005550 +100124458 Mir876 MGI:MGI:3718566|Ensembl:ENSMUSG00000077851|miRBase:MI0005480 +100124459 Mir877 MGI:MGI:3718567|Ensembl:ENSMUSG00000077931|miRBase:MI0005553 +100124460 Mir881 MGI:MGI:3718572|Ensembl:ENSMUSG00000078038|miRBase:MI0005474 +100124461 Mir882 MGI:MGI:3718573|Ensembl:ENSMUSG00000077881|miRBase:MI0005475 +100124462 Mir883a MGI:MGI:3718574|Ensembl:ENSMUSG00000078017|miRBase:MI0005476 +100124463 Mir105 MGI:MGI:3718453|Ensembl:ENSMUSG00000077847|miRBase:MI0005481 +100124464 Mir465c-2 MGI:MGI:3718525|Ensembl:ENSMUSG00000095006|miRBase:MI0005501 +100124465 Mir466d MGI:MGI:3718531|Ensembl:ENSMUSG00000078031|miRBase:MI0005546 +100124466 Mir493 MGI:MGI:3718542|Ensembl:ENSMUSG00000077025|miRBase:MI0005514 +100124467 Mir568 MGI:MGI:3718548|Ensembl:ENSMUSG00000076372|miRBase:MI0005517 +100124468 Mir653 MGI:MGI:3718555|Ensembl:ENSMUSG00000076357|miRBase:MI0005557 +100124469 Mir875 MGI:MGI:3718565|Ensembl:ENSMUSG00000077890|miRBase:MI0005551 +100124470 Mir92b MGI:MGI:3718577|Ensembl:ENSMUSG00000076255|miRBase:MI0005521 +100124471 Mir291b MGI:MGI:3718464|Ensembl:ENSMUSG00000078032|miRBase:MI0003539 +100124473 Mir465b-1 MGI:MGI:3718520|Ensembl:ENSMUSG00000094894|miRBase:MI0005498 +100124474 Mir466b-3 MGI:MGI:3718529|Ensembl:ENSMUSG00000076994|miRBase:MI0005504 +100124475 Mir466f-3 MGI:MGI:3718535|Ensembl:ENSMUSG00000077981|miRBase:MI0005509 +100124476 Mir504 MGI:MGI:3718543|Ensembl:ENSMUSG00000070110|miRBase:MI0005515 +100124477 Mir590 MGI:MGI:3718552|miRBase:MI0005519 +100124478 Mir871 MGI:MGI:3718561|Ensembl:ENSMUSG00000096628|miRBase:MI0005471 +100124479 Mir878 MGI:MGI:3718569|Ensembl:ENSMUSG00000077872|miRBase:MI0005548 +100124480 Mir880 MGI:MGI:3718571|Ensembl:ENSMUSG00000078002|miRBase:MI0005473 +100124481 Mir190b MGI:MGI:3718457|Ensembl:ENSMUSG00000077996|miRBase:MI0005478 +100124482 Mir297a-3 MGI:MGI:3718465|Ensembl:ENSMUSG00000076956|miRBase:MI0005488 +100124483 Mir297c MGI:MGI:3718506|Ensembl:ENSMUSG00000076976|miRBase:MI0005492 +100124484 Mir453 MGI:MGI:3718517|Ensembl:ENSMUSG00000077925|miRBase:MI0005497 +100124485 Mir466b-1 MGI:MGI:3718526|Ensembl:ENSMUSG00000106608|miRBase:MI0005502 +100124486 Mir466f-1 MGI:MGI:3718533|Ensembl:ENSMUSG00000077972|miRBase:MI0005507 +100124487 Mir467c MGI:MGI:3718539|Ensembl:ENSMUSG00000077049|miRBase:MI0005512 +100124488 Mir511 MGI:MGI:3718546|Ensembl:ENSMUSG00000077897|miRBase:MI0005554 +100124489 Mir582 MGI:MGI:3718550|Ensembl:ENSMUSG00000076946|miRBase:MI0006127 +100124490 Mir712 MGI:MGI:3718558|miRBase:MI0004696 +100124491 Mir874 MGI:MGI:3718564|Ensembl:ENSMUSG00000077962|miRBase:MI0005479 +100124492 Mir879 MGI:MGI:3718570|Ensembl:ENSMUSG00000077896|miRBase:MI0005472 +100124493 Mir883b MGI:MGI:3718576|Ensembl:ENSMUSG00000078024|miRBase:MI0005477 +100124494 Mir421 MGI:MGI:3718516|Ensembl:ENSMUSG00000065509|miRBase:MI0005496 +100124495 Mir466g MGI:MGI:3718536|Ensembl:ENSMUSG00000078025|miRBase:MI0005510 +100124496 Mir743b MGI:MGI:3718560|Ensembl:ENSMUSG00000094184|miRBase:MI0005470 +100124543 Bmd39 MGI:MGI:3719112 +100124544 Mirb MGI:MGI:3719199 +100124546 Vmn2r-ps3 MGI:MGI:3757653 +100124547 Vmn2r-ps4 MGI:MGI:3757669 +100124548 Vmn2r-ps6 MGI:MGI:3757678 +100124549 Vmn2r-ps8 MGI:MGI:3757680 +100124550 Vmn2r-ps9 MGI:MGI:3757686 +100124551 Vmn2r-ps39 MGI:MGI:3757703 +100124552 Vmn2r-ps48 MGI:MGI:3757888 +100124553 Vmn2r-ps52 MGI:MGI:3757932 +100124554 Vmn2r-ps10 MGI:MGI:3757943 +100124555 Vmn2r-ps55 MGI:MGI:3757982 +100124556 Vmn2r-ps58 MGI:MGI:3757988 +100124557 Vmn2r-ps59 MGI:MGI:3757989 +100124558 Vmn2r-ps62 MGI:MGI:3757998 +100124559 Vmn2r-ps63 MGI:MGI:3757999 +100124560 Vmn2r-ps64 MGI:MGI:3758005 +100124561 Vmn2r-ps65 MGI:MGI:3758007 +100124562 Vmn2r-ps67 MGI:MGI:3761308 +100124563 Vmn2r-ps70 MGI:MGI:3761313 +100124564 Vmn2r-ps71 MGI:MGI:3761316 +100124565 Vmn2r-ps75 MGI:MGI:3761320 +100124566 Vmn2r-ps76 MGI:MGI:3761321 +100124567 Vmn2r-ps77 MGI:MGI:3761322 +100124568 Vmn2r-ps78 MGI:MGI:3761323 +100124569 Vmn2r-ps79 MGI:MGI:3761324 +100124570 Vmn2r-ps85 MGI:MGI:3761330 +100124571 Vmn2r-ps90 MGI:MGI:3761337 +100124572 Vmn2r-ps136 MGI:MGI:3761340 +100124573 Vmn2r-ps138 MGI:MGI:3761342 +100124574 Vmn2r-ps140 MGI:MGI:3761344 +100124575 Vmn2r-ps92 MGI:MGI:3761345 +100124576 Vmn2r-ps18 MGI:MGI:3761373 +100124577 Vmn2r-ps27 MGI:MGI:3761474 +100124578 Vmn2r-ps28 MGI:MGI:3761478 +100124579 Vmn2r-ps118 MGI:MGI:3761536 +100124580 Vmn2r-ps121 MGI:MGI:3761539 +100124581 Vmn2r-ps132 MGI:MGI:3761692 +100124582 Vmn2r-ps135 MGI:MGI:3761697 +100124584 Vmn2r-ps142 MGI:MGI:3761699 +100124585 Vmn2r-ps144 MGI:MGI:3761706 +100124586 Vmn2r-ps146 MGI:MGI:3761707 +100124587 Vmn2r-ps147 MGI:MGI:3761708 +100124588 Vmn2r-ps151 MGI:MGI:3761711 +100124589 Vmn2r-ps152 MGI:MGI:3761712 +100124590 Vmn2r-ps154 MGI:MGI:3761714 +100124591 Vmn2r-ps156 MGI:MGI:3761716 +100124623 Gm13179 MGI:MGI:3701958 +100124624 Mir467a-2 MGI:MGI:3719571|Ensembl:ENSMUSG00000096027|miRBase:MI0014053 +100124625 Mir467a-4 MGI:MGI:3719573|Ensembl:ENSMUSG00000096492|miRBase:MI0014059 +100124626 Mir467a-5 MGI:MGI:3719574|Ensembl:ENSMUSG00000094159|miRBase:MI0014062 +100124627 Mir467a-6 MGI:MGI:3719576|Ensembl:ENSMUSG00000096587|miRBase:MI0014065 +100124640 Mir466e MGI:MGI:3719617|Ensembl:ENSMUSG00000104933|miRBase:MI0005506 +100124641 Mir692-3 MGI:MGI:3719623|Ensembl:ENSMUSG00000076033|miRBase:MI0023541 +100124642 Mir467a-3 MGI:MGI:3719572|Ensembl:ENSMUSG00000095198|miRBase:MI0014056 +100124643 Mir467a-8 MGI:MGI:3719578|Ensembl:ENSMUSG00000096512|miRBase:MI0014072 +100124649 Mir683-2 MGI:MGI:3719634|Ensembl:ENSMUSG00000094933|miRBase:MI0010690 +100124659 Trbv2 MGI:MGI:98599|IMGT/GENE-DB:TRBV2 +100124660 Trbv4 MGI:MGI:98584|IMGT/GENE-DB:TRBV4 +100124661 Trbv5 MGI:MGI:98583|IMGT/GENE-DB:TRBV5 +100124662 Trbv6 MGI:MGI:5009962|IMGT/GENE-DB:TRBV6 +100124663 Trbv7 MGI:MGI:5009963|IMGT/GENE-DB:TRBV7 +100124664 Trbv8 MGI:MGI:5009964|IMGT/GENE-DB:TRBV8 +100124665 Trbv9 MGI:MGI:5009965|IMGT/GENE-DB:TRBV9 +100124668 Mir466c-2 MGI:MGI:3720016|Ensembl:ENSMUSG00000094659|miRBase:MI0014057 +100124670 Trbv10 MGI:MGI:4937160|IMGT/GENE-DB:TRBV10 +100124671 Trbv11 MGI:MGI:5009966|IMGT/GENE-DB:TRBV11 +100124672 Trbv12-1 MGI:MGI:98602|IMGT/GENE-DB:TRBV12-1 +100124673 Trbv13-1 MGI:MGI:98609|IMGT/GENE-DB:TRBV13-1 +100124674 Trbv12-2 MGI:MGI:98601|IMGT/GENE-DB:TRBV12-2 +100124675 Trbv13-2 MGI:MGI:98608|IMGT/GENE-DB:TRBV13-2 +100124676 Trbv12-3 MGI:MGI:98603|IMGT/GENE-DB:TRBV12-3 +100124677 Trbv13-3 MGI:MGI:98607|IMGT/GENE-DB:TRBV13-3 +100124678 Trbv14 MGI:MGI:98587|IMGT/GENE-DB:TRBV14 +100124679 Trbv15 MGI:MGI:98586|IMGT/GENE-DB:TRBV15 +100124680 Trbv16 MGI:MGI:98585|IMGT/GENE-DB:TRBV16 +100124681 Trbv17 MGI:MGI:98610|IMGT/GENE-DB:TRBV17 +100124682 Trbv18 MGI:MGI:5009967|IMGT/GENE-DB:TRBV18 +100124684 Trbv19 MGI:MGI:98604|IMGT/GENE-DB:TRBV19 +100124685 Trbv20 MGI:MGI:98589|IMGT/GENE-DB:TRBV20 +100124686 Trbv21 MGI:MGI:98593|IMGT/GENE-DB:TRBV21 +100124687 Trbv22 MGI:MGI:5009968|IMGT/GENE-DB:TRBV22 +100124688 Trbv23 MGI:MGI:98595|IMGT/GENE-DB:TRBV23 +100124689 Trbv24 MGI:MGI:98591|IMGT/GENE-DB:TRBV24 +100124690 Trbv25 MGI:MGI:5009969|IMGT/GENE-DB:TRBV25 +100124693 Trbv27 MGI:MGI:5009970|IMGT/GENE-DB:trbv27 +100124694 Trbv28 MGI:MGI:5009971|IMGT/GENE-DB:TRBV28 +100124698 Trbv29 MGI:MGI:98605|IMGT/GENE-DB:TRBV29 +100124699 Trbv30 MGI:MGI:98592|IMGT/GENE-DB:TRBV30 +100125242 Vmn2r-ps111 MGI:MGI:3761530 +100125243 Vmn2r-ps112 MGI:MGI:3757576 +100125245 Vmn2r-ps116 MGI:MGI:3761534 +100125246 Trbd1 MGI:MGI:4439571|IMGT/GENE-DB:TRBD1 +100125247 Trbd2 MGI:MGI:4439727|IMGT/GENE-DB:TRBD2 +100125248 Trbj1-1 MGI:MGI:4439570|IMGT/GENE-DB:TRBJ1-1 +100125249 Trbj1-2 MGI:MGI:4439569|IMGT/GENE-DB:TRBJ1-2 +100125250 Trbj1-3 MGI:MGI:4439568|IMGT/GENE-DB:TRBJ1-3 +100125251 Trbj1-4 MGI:MGI:4439567|IMGT/GENE-DB:TRBJ1-4 +100125252 Trbj1-5 MGI:MGI:4439566|IMGT/GENE-DB:TRBJ1-5 +100125253 Trbj1-6 MGI:MGI:4439575|IMGT/GENE-DB:TRBJ1-6 +100125254 Trbj1-7 MGI:MGI:4439574|IMGT/GENE-DB:TRBJ1-7 +100125255 Trbj2-1 MGI:MGI:4439728|IMGT/GENE-DB:TRBJ2-1 +100125256 Trbj2-2 MGI:MGI:4439729|IMGT/GENE-DB:TRBJ2-2 +100125257 Trbj2-3 MGI:MGI:4439898|IMGT/GENE-DB:TRBJ2-3 +100125258 Trbj2-4 MGI:MGI:4439730|IMGT/GENE-DB:TRBJ2-4 +100125259 Trbj2-5 MGI:MGI:4439899|IMGT/GENE-DB:TRBJ2-5 +100125260 Trbj2-6 MGI:MGI:4937236|IMGT/GENE-DB:TRBJ2-6 +100125261 Trbj2-7 MGI:MGI:4439731|IMGT/GENE-DB:TRBJ2-7 +100125262 Trbc1 MGI:MGI:4439726|IMGT/GENE-DB:TRBC1 +100125263 Trbc2 MGI:MGI:4835227|IMGT/GENE-DB:TRBC2 +100125268 Vmn2r-ps126 MGI:MGI:3761612 +100125269 Vmn2r-ps127 MGI:MGI:3761614 +100125273 Vmn2r-ps12 MGI:MGI:3757944 +100125275 Gm13225 MGI:MGI:3652161 +100125279 Vmn2r-ps15 MGI:MGI:3761370 +100125280 Vmn2r-ps16 MGI:MGI:3761371 +100125283 Vmn2r-ps19 MGI:MGI:3761374 +100125290 Chldq7 MGI:MGI:3711850 +100125291 Chldq8 MGI:MGI:3711851 +100125292 Chldq9 MGI:MGI:3711852 +100125293 Tglq5 MGI:MGI:3720116 +100125294 Tglq6 MGI:MGI:3720117 +100125295 Tglq3 MGI:MGI:3711853 +100125296 Chldq6 MGI:MGI:3711849 +100125297 Imacq MGI:MGI:3720162 +100125298 Vmn2r-ps20 MGI:MGI:3761375 +100125319 Vmn2r-ps50 MGI:MGI:3757890 +100125321 Vmn2r-ps73 MGI:MGI:3761318 +100125339 A230020J21Rik MGI:MGI:3704207|Ensembl:ENSMUSG00000097845 +100125340 A230083N12Rik MGI:MGI:3698879 +100125391 Vmn2r-ps150 MGI:MGI:3761710 +100125394 Cyp2c71-ps MGI:MGI:3721924 +100125395 Cyp2c72-ps MGI:MGI:3721925 +100125396 Femwf1 MGI:MGI:3720835 +100125397 Femwf2 MGI:MGI:3720836 +100125398 Femwf3 MGI:MGI:3720838 +100125399 Femwf4 MGI:MGI:3720839 +100125400 Femwf5 MGI:MGI:3720840 +100125401 Femwf6 MGI:MGI:3720842 +100125402 Femwf8 MGI:MGI:3720844 +100125403 Femwf9 MGI:MGI:3720845 +100125404 Femwf11 MGI:MGI:3720847 +100125405 Femwf13 MGI:MGI:3720849 +100125406 Femwf12 MGI:MGI:3720848 +100125407 Femwf7 MGI:MGI:3720843 +100125408 Femwf10 MGI:MGI:3720846 +100125410 Cyp2d32-ps MGI:MGI:3721929 +100125411 Cyp2d33-ps MGI:MGI:3721930 +100125586 Vmn2r2 MGI:MGI:3757666|Ensembl:ENSMUSG00000043897|Vega:OTTMUSG00000039824 +100125594 LOC100125594 Ensembl:ENSMUSG00000087495 +100125596 Cyp2d35-ps MGI:MGI:5295679 +100125597 Cyp2d39-ps MGI:MGI:5295680 +100125599 Cyp2j14-ps MGI:MGI:3651954 +100125600 Cyp2j15-ps MGI:MGI:3652069 +100125755 Abd1 MGI:MGI:3721511 +100125842 Tbqt1 MGI:MGI:3721632 +100125843 Tbqt2 MGI:MGI:3721633 +100125844 Tbqt3 MGI:MGI:3721634 +100125845 Tbqt4 MGI:MGI:3721635 +100125846 Tbqt5 MGI:MGI:3721636 +100125847 Tbqt7 MGI:MGI:3721638 +100125848 Sh1 MGI:MGI:3721671 +100125849 Sh3 MGI:MGI:3721673 +100125850 Sh4 MGI:MGI:3721674 +100125851 Ltsw1 MGI:MGI:3721676 +100125852 Ltsw2 MGI:MGI:3721677 +100125853 Tbqt6 MGI:MGI:3721637 +100125854 Sh2 MGI:MGI:3721672 +100125855 Dss1 MGI:MGI:3721675 +100125856 Hpw1 MGI:MGI:3721678 +100125870 Gm20574 MGI:MGI:5295681 +100125872 Cyp3a58-ps MGI:MGI:5295682 +100125873 Cyp3a60-ps MGI:MGI:5295683 +100125874 Cyp3a61-ps1 MGI:MGI:5295684 +100125875 Cyp4f38-ps MGI:MGI:5295685 +100125929 0610009E02Rik MGI:MGI:3698435 +100125931 Phtf1os MGI:MGI:3698050|Ensembl:ENSMUSG00000089998 +100125933 2310075K07Rik MGI:MGI:3697429 +100125952 Gm10468 MGI:MGI:3704388 +100125977 Gm10034 MGI:MGI:3704445 +100126003 Hfgi2 MGI:MGI:3722329 +100126004 Ramls2 MGI:MGI:3722391 +100126005 Hfgi1 MGI:MGI:3722328 +100126006 Ramls1 MGI:MGI:3722390 +100126030 BC037039 MGI:MGI:3697820 +100126033 Gm10366 MGI:MGI:3704443 +100126034 Gm10644 MGI:MGI:3704314 +100126077 Mom7 MGI:MGI:3697679 +100126078 Mtgq1 MGI:MGI:3723092 +100126079 Mtgq2 MGI:MGI:3723094 +100126080 Mtgq3 MGI:MGI:3723096 +100126081 Mtgq4 MGI:MGI:3723097 +100126082 Mtbcq1 MGI:MGI:3723099 +100126083 Mtbcq2 MGI:MGI:3723100 +100126084 Mtbcq5 MGI:MGI:3723103 +100126085 Mtbcq7 MGI:MGI:3723105 +100126086 Lvwtq1 MGI:MGI:3723108 +100126087 Swqnd2 MGI:MGI:3723111 +100126088 Mtgq5 MGI:MGI:3723093 +100126089 Mtbcq3 MGI:MGI:3723101 +100126090 Swqnd1 MGI:MGI:3723110 +100126091 Mtbcq4 MGI:MGI:3723102 +100126092 Mtbcq6 MGI:MGI:3723104 +100126093 Mtbcq8 MGI:MGI:3723106 +100126094 Mswtq1 MGI:MGI:3723112 +100126096 Gm17790 MGI:MGI:5009972 +100126097 Fl1sa MGI:MGI:3723314 +100126098 Fl2sa MGI:MGI:3723316 +100126099 Gm17791 MGI:MGI:5009973 +100126193 Tsti2 MGI:MGI:3758238 +100126194 Skts-fp1 MGI:MGI:3758257 +100126195 Skts-fp2 MGI:MGI:3758258 +100126196 Tsti1 MGI:MGI:3758237 +100126197 Tsti3 MGI:MGI:3758239 +100126198 Skts-fp3 MGI:MGI:3758259 +100126199 Tsti4 MGI:MGI:3758240 +100126202 9630029G12Rik MGI:MGI:3698177 +100126203 6820426E19Rik MGI:MGI:3695826 +100126206 Gm10551 MGI:MGI:3712176 +100126224 Gm11747 MGI:MGI:3702093|Ensembl:ENSMUSG00000086514 +100126225 A630052K13Rik MGI:MGI:3704372 +100126226 Krt83 MGI:MGI:3690448|Ensembl:ENSMUSG00000067613|Vega:OTTMUSG00000033745 +100126227 Gm13031 MGI:MGI:3702680|Ensembl:ENSMUSG00000087698 +100126228 Gm9856 MGI:MGI:3704347 +100126229 Gm12758 MGI:MGI:3702543 +100126240 Gm13112 MGI:MGI:3701127 +100126242 Frs3os MGI:MGI:3713047|Ensembl:ENSMUSG00000086930 +100126243 A030001D20Rik MGI:MGI:3696869|Ensembl:ENSMUSG00000110357 +100126244 Gm13262 MGI:MGI:3703165 +100126250 Bpq22 MGI:MGI:3758800 +100126251 Bpq23 MGI:MGI:3758801 +100126252 Bpq21 MGI:MGI:3758799 +100126269 BC048602 MGI:MGI:3758910 +100126353 Gm16103 MGI:MGI:3802086 +100126357 Gm10676 MGI:MGI:3704283 +100126429 Bbq1 MGI:MGI:3759431 +100126431 Trgj1 MGI:MGI:4440480|IMGT/GENE-DB:TRGJ1 +100126432 Trgj3 MGI:MGI:4439528|IMGT/GENE-DB:TRGJ3 +100126433 Trgj2 MGI:MGI:4439598|IMGT/GENE-DB:TRGJ2 +100126434 Trgj4 MGI:MGI:4439597|IMGT/GENE-DB:TRGJ4 +100126435 9430073C21Rik MGI:MGI:3699860 +100126436 Psds1 MGI:MGI:3759755 +100126437 Psds2 MGI:MGI:3759756 +100126438 Psds4 MGI:MGI:3759768 +100126439 Psds3 MGI:MGI:3759757 +100126451 Trav6n-5 MGI:MGI:3704437|IMGT/GENE-DB:TRAV6N-5 +100126452 Trav15n-1 MGI:MGI:4439864|IMGT/GENE-DB:TRAV15N-1 +100126454 Trav5n-2 MGI:MGI:5009974|IMGT/GENE-DB:TRAV5N-2 +100126455 Trav5n-3 MGI:MGI:4937282|IMGT/GENE-DB:TRAV5N-3 +100126456 Trav6n-7 IMGT/GENE-DB:TRAV6N-7 +100126457 Trav7n-6 MGI:MGI:3704442|IMGT/GENE-DB:TRAV7N-6 +100126458 Trav8n-2 MGI:MGI:3641705|IMGT/GENE-DB:TRAV8N-2 +100126459 Trav16n MGI:MGI:4439761|IMGT/GENE-DB:TRAV16N +100126460 Trav13n-4 MGI:MGI:3642678|IMGT/GENE-DB:TRAV13N-4 +100126461 Trav15n-3 MGI:MGI:5009975|IMGT/GENE-DB:TRAV15N-3 +100126462 Trav4-2 MGI:MGI:3649605|IMGT/GENE-DB:TRAV4-2 +100126463 Trav6-4 MGI:MGI:3702153|IMGT/GENE-DB:TRAV6-4 +100126464 Trav6-5 MGI:MGI:3649609|IMGT/GENE-DB:TRAV6-5 +100126465 Trav6-6 MGI:MGI:4439905|IMGT/GENE-DB:TRAV6-6 +100126466 Trav11 MGI:MGI:3642163|IMGT/GENE-DB:TRAV11 +100126469 Trav13-1 MGI:MGI:4439904|IMGT/GENE-DB:TRAV13-1 +100126470 Trav3-2 MGI:MGI:5009976|IMGT/GENE-DB:TRAV3-2 +100126471 Trav4-3 MGI:MGI:4440478|IMGT/GENE-DB:TRAV4-3 +100126472 Trav5-2 MGI:MGI:5009977|IMGT/GENE-DB:TRAV5-2 +100126546 Gm10708 MGI:MGI:3642746 +100126547 Gm14735 MGI:MGI:3705690 +100126588 Trav9-3 IMGT/GENE-DB:TRAV9-3 +100126589 Trav5-3 IMGT/GENE-DB:TRAV5-3 +100126591 Gm17792 MGI:MGI:5009978 +100126692 B020018J22Rik MGI:MGI:3761288|Ensembl:ENSMUSG00000113189 +100126765 Esp36 MGI:MGI:5141873|Ensembl:ENSMUSG00000092322|Vega:OTTMUSG00000037366 +100126766 Esp3 MGI:MGI:5439396|Ensembl:ENSMUSG00000093957 +100126768 Esp31 MGI:MGI:5141981|Ensembl:ENSMUSG00000092342|Vega:OTTMUSG00000037370 +100126773 Esp34 MGI:MGI:5141875|Ensembl:ENSMUSG00000092244 +100126774 Esp18 MGI:MGI:5295686|Ensembl:ENSMUSG00000094024 +100126775 Esp38 MGI:MGI:5439397|Ensembl:ENSMUSG00000095886 +100126776 Esp24 MGI:MGI:5439398|Ensembl:ENSMUSG00000095625 +100126777 Esp4 MGI:MGI:5295687|Ensembl:ENSMUSG00000095540 +100126778 Esp8 MGI:MGI:4937129|Ensembl:ENSMUSG00000090747 +100126779 Esp23 MGI:MGI:5295688|Ensembl:ENSMUSG00000096697 +100126785 Wg2a MGI:MGI:3762226 +100126786 Wg2c MGI:MGI:3762228 +100126787 Ity2a MGI:MGI:3762326 +100126788 Ity2b MGI:MGI:3762327 +100126789 Wg2b MGI:MGI:3762227 +100126790 Wg2d MGI:MGI:3762229 +100126795 Gm10575 MGI:MGI:3708765|Ensembl:ENSMUSG00000073787 +100126796 Erk-50 - +100126818 Gm17592 MGI:MGI:4937226 +100126819 Gm10076 MGI:MGI:3704451 +100126820 Gm17793 MGI:MGI:5009979 +100126821 Gm17794 MGI:MGI:5009980 +100126824 Sco2 MGI:MGI:3818630|Ensembl:ENSMUSG00000091780 +100126829 Pif - +100126874 Gm9928 MGI:MGI:3708659 +100126875 Gm10067 MGI:MGI:3708768 +100126877 Gm10204 MGI:MGI:3642066 +100126879 Gm10759 MGI:MGI:3708581 +100126880 Gm14243 MGI:MGI:3651252 +100127111 Snord22 MGI:MGI:1933385|Ensembl:ENSMUSG00000065087 +100127433 Gm11532 MGI:MGI:3713523|Ensembl:ENSMUSG00000087067 +100127434 Gm10351 MGI:MGI:3642306 +100134856 Gm17795 MGI:MGI:5009981 +100134861 Gm44502 MGI:MGI:3846135|Ensembl:ENSMUSG00000022617 +100134981 Gm17796 MGI:MGI:5009982 +100134986 Gm15498 MGI:MGI:3782945 +100134990 Gm12060 MGI:MGI:3649370|Ensembl:ENSMUSG00000085415 +100135427 Hmgb1-ps2 MGI:MGI:3768537 +100135653 Rhox3b-ps MGI:MGI:3770264 +100135654 Rhox3c MGI:MGI:3770268|Ensembl:ENSMUSG00000079636|Vega:OTTMUSG00000017140 +100135655 Gm15681 MGI:MGI:3783123 +100135657 Rhox3e MGI:MGI:3770274|Ensembl:ENSMUSG00000059626|Vega:OTTMUSG00000017148 +100135765 LOC100135765 - +100137011 Gm12689 MGI:MGI:3650433 +100137727 9130230N09Rik MGI:MGI:1924921 +100141473 LOC100141473 - +100141474 4933428G20Rik MGI:MGI:1918475|Ensembl:ENSMUSG00000047988|Vega:OTTMUSG00000002719 +100142658 Gm10222 MGI:MGI:3642643 +100144395 Nct1 MGI:MGI:3775246 +100144396 Nct2 MGI:MGI:3775249 +100151689 Gm17797 MGI:MGI:5009983 +100151690 Gm17798 MGI:MGI:5009984 +100151692 Gm11198 MGI:MGI:3649956 +100151693 Gm10364 MGI:MGI:3643153|Ensembl:ENSMUSG00000072492 +100151698 Gm17799 MGI:MGI:5009985 +100151772 Srsx MGI:MGI:3777603 +100158259 Gm17068 MGI:MGI:4937895 +100158260 Gm17800 MGI:MGI:5009986 +100158261 Gm14921 MGI:MGI:3708102 +100169864 Gm44504 MGI:MGI:5621304|Ensembl:ENSMUSG00000015290 +100169865 Gm10914 MGI:MGI:3779122 +100169866 Gm10933 MGI:MGI:3779143 +100169868 Gm3173 MGI:MGI:3781352 +100169870 Gm11054 MGI:MGI:3779277 +100169871 Gm10910 MGI:MGI:3779119 +100169872 Gm10926 MGI:MGI:3779138 +100169873 Gm11033 MGI:MGI:3779256 +100169874 Gm11110 MGI:MGI:3779362|Ensembl:ENSMUSG00000079414 +100169875 Gm11159 MGI:MGI:3779411 +100169876 Gm11123 MGI:MGI:3779377 +100169878 Gm10941 MGI:MGI:3779151|Ensembl:ENSMUSG00000078444 +100169880 5830419E12Rik MGI:MGI:3779136 +100169889 Peg3os MGI:MGI:5294921 +100170400 Mxra8os MGI:MGI:3704241 +100170401 EU599041 MGI:MGI:3796554 +100174921 4930505N22Rik MGI:MGI:1922306 +100188919 Gm45915 MGI:MGI:5825552 +100188958 Gm15824 MGI:MGI:3801976 +100188961 Gm14659 MGI:MGI:3705713 +100189605 Mup19 MGI:MGI:3705235|Ensembl:ENSMUSG00000078673|Vega:OTTMUSG00000007472 +100190765 Mir449b MGI:MGI:3718803|Ensembl:ENSMUSG00000078027|miRBase:MI0005547 +100190798 4930470G03Rik MGI:MGI:1922171 +100191011 Gm17383 MGI:MGI:4937017 +100191037 Krtap10-4 MGI:MGI:1925013|Ensembl:ENSMUSG00000069582|Vega:OTTMUSG00000044986 +100191075 Gm10925 MGI:MGI:3809095 +100191076 Gm16238 MGI:MGI:3802104 +100196896 BC048559 MGI:MGI:3814724 +100216343 Gm17501 MGI:MGI:4937135 +100216455 Gm14124 MGI:MGI:3652002|Ensembl:ENSMUSG00000079008|Vega:OTTMUSG00000015734 +100216460 Itpa-ps2 MGI:MGI:3613364 +100216474 Ttll2 MGI:MGI:3644030|Ensembl:ENSMUSG00000079722 +100216530 Snord118 MGI:MGI:3819519|Ensembl:ENSMUSG00000064899 +100216531 Snord1b MGI:MGI:3819526|Ensembl:ENSMUSG00000077604 +100216532 Snord2 MGI:MGI:3819528|Ensembl:ENSMUSG00000088524 +100216533 Snord55 MGI:MGI:3819543|Ensembl:ENSMUSG00000092680 +100216534 Snord96a MGI:MGI:3819568|Ensembl:ENSMUSG00000064725 +100216535 Scarna9 MGI:MGI:3819489 +100216536 Snord1c MGI:MGI:3819527|Ensembl:ENSMUSG00000065640 +100216537 Snord104 MGI:MGI:3819515|Ensembl:ENSMUSG00000065126 +100216538 Snord1a MGI:MGI:3819525|Ensembl:ENSMUSG00000065094 +100216539 Snord4a MGI:MGI:3819540|Ensembl:ENSMUSG00000077625 +100216540 Snord95 MGI:MGI:3819567|Ensembl:ENSMUSG00000064780 +100217365 E130208F15Rik MGI:MGI:3767226 +100217369 Gm10935 MGI:MGI:3809041 +100217413 Scarna10 MGI:MGI:3819482 +100217414 Scarna3a MGI:MGI:3819485|Ensembl:ENSMUSG00000089536 +100217415 Scarna6 MGI:MGI:3819487|Ensembl:ENSMUSG00000089281 +100217416 Snora2b MGI:MGI:3819497|Ensembl:ENSMUSG00000065939 +100217417 Snora34 MGI:MGI:3819502|Ensembl:ENSMUSG00000065336 +100217418 Snora44 MGI:MGI:3819506|Ensembl:ENSMUSG00000064604 +100217419 Snora52 MGI:MGI:3819508|Ensembl:ENSMUSG00000064666 +100217420 Snora81 MGI:MGI:3819513|Ensembl:ENSMUSG00000087935 +100217421 Snord11 MGI:MGI:3819516 +100217422 Snord13 MGI:MGI:3819521|Ensembl:ENSMUSG00000088252 +100217423 Snord19 MGI:MGI:3819524 +100217424 Snord38a MGI:MGI:3819531|Ensembl:ENSMUSG00000065680 +100217425 Snord45c MGI:MGI:3819536 +100217426 Snord49b MGI:MGI:3819539|Ensembl:ENSMUSG00000064437 +100217427 Snord52 MGI:MGI:3819541|Ensembl:ENSMUSG00000093009 +100217428 Snord57 MGI:MGI:3819544|Ensembl:ENSMUSG00000065272 +100217429 Snord64 MGI:MGI:3819546 +100217430 Snord66 MGI:MGI:3819548 +100217431 Snord69 MGI:MGI:3819551 +100217432 Snord71 MGI:MGI:3819554 +100217433 Snord88a MGI:MGI:3819560|Ensembl:ENSMUSG00000095472 +100217434 Snord88c MGI:MGI:3819561|Ensembl:ENSMUSG00000096296 +100217435 Snord90 MGI:MGI:3819563 +100217436 Snord93 MGI:MGI:3819566 +100217437 Snord99 MGI:MGI:3819570 +100217438 Scarna2 MGI:MGI:3819484 +100217439 Snora19 MGI:MGI:3819491 +100217440 Snora61 MGI:MGI:3819510 +100217441 Snord23 MGI:MGI:3819529|Ensembl:ENSMUSG00000080478 +100217442 Snora30 MGI:MGI:3819499|Ensembl:ENSMUSG00000065259 +100217443 Snord12 MGI:MGI:3819520 +100217444 Snord65 MGI:MGI:3819547 +100217445 Snord8 MGI:MGI:3819556|Ensembl:ENSMUSG00000093044 +100217446 Snord47 MGI:MGI:3819537|Ensembl:ENSMUSG00000064968 +100217447 Scarna3b MGI:MGI:3819486|Ensembl:ENSMUSG00000088158|Ensembl:ENSMUSG00000112285 +100217448 Scarna8 MGI:MGI:3819488|Ensembl:ENSMUSG00000088958 +100217449 Snora36b MGI:MGI:3819504|Ensembl:ENSMUSG00000077571 +100217450 Snora47 MGI:MGI:3819507|Ensembl:ENSMUSG00000088108 +100217451 Snora7a MGI:MGI:3819512|Ensembl:ENSMUSG00000064563 +100217452 Snord110 MGI:MGI:3819517|Ensembl:ENSMUSG00000080610 +100217453 Snord16a MGI:MGI:3819522|Ensembl:ENSMUSG00000094411 +100217454 Snord37 MGI:MGI:3819530|Ensembl:ENSMUSG00000064441 +100217455 Snord49a MGI:MGI:3819538|Ensembl:ENSMUSG00000065734 +100217456 Snord53 MGI:MGI:3819542|Ensembl:ENSMUSG00000092887 +100217457 Snord58b MGI:MGI:3819545|Ensembl:ENSMUSG00000064871 +100217458 Snord67 MGI:MGI:3819549|Ensembl:ENSMUSG00000077221 +100217459 Snord70 MGI:MGI:3819553 +100217460 Snord85 MGI:MGI:3819558|Ensembl:ENSMUSG00000065196 +100217461 Snord89 MGI:MGI:3819562|Ensembl:ENSMUSG00000077704 +100217462 Snord92 MGI:MGI:3819565|Ensembl:ENSMUSG00000093289 +100217463 Snord98 MGI:MGI:3819569 +100217464 Snora41 MGI:MGI:3819505|Ensembl:ENSMUSG00000064602 +100217465 Snord111 MGI:MGI:3819518 +100217466 Scarna17 MGI:MGI:3819483 +100217467 Snora5c MGI:MGI:3819509 +100217468 Snord45b MGI:MGI:3819535 +100217469 Snord91a MGI:MGI:3819564 +100233175 Gon7 MGI:MGI:4845848|Ensembl:ENSMUSG00000091931|Vega:OTTMUSG00000044953 +100233207 Gm17359 MGI:MGI:4936993|Ensembl:ENSMUSG00000091685|Vega:OTTMUSG00000052189 +100233208 Gm10778 MGI:MGI:3809656|Ensembl:ENSMUSG00000096856|Vega:OTTMUSG00000047159 +100268169 A730035I17Rik MGI:MGI:3696858 +100270707 Gm14379 MGI:MGI:3649346|Ensembl:ENSMUSG00000087252 +100270744 Btbd18 MGI:MGI:3650217|Ensembl:ENSMUSG00000086598|Vega:OTTMUSG00000013494 +100270751 Gm15590 MGI:MGI:3831433 +100271704 Gm17660 MGI:MGI:4937294|Ensembl:ENSMUSG00000091034|Vega:OTTMUSG00000053769 +100271841 Uckl1os MGI:MGI:3801877|Ensembl:ENSMUSG00000010492 +100271882 Gm14139 MGI:MGI:3836251|Ensembl:ENSMUSG00000079009|Vega:OTTMUSG00000015769 +100271928 Gm15881 MGI:MGI:3801769 +100272219 AA543186 MGI:MGI:3035233|Ensembl:ENSMUSG00000097345 +100272221 Gm17801 MGI:MGI:5009987 +100286833 Gm17802 MGI:MGI:5009988 +100286834 Gm17803 MGI:MGI:5009989 +100286835 Gm17804 MGI:MGI:5009990 +100286839 Gm17805 MGI:MGI:5009991 +100286840 Gm17806 MGI:MGI:5009992 +100286842 Gm14663 MGI:MGI:3705451 +100286843 Gm16325 MGI:MGI:3826549|Ensembl:ENSMUSG00000085810 +100294504 Gm10188 MGI:MGI:3704196 +100294507 Gm17807 MGI:MGI:5009993 +100294583 Alkal2 MGI:MGI:3697448|Ensembl:ENSMUSG00000054204 +100294660 Defa2 MGI:MGI:94882|Ensembl:ENSMUSG00000096295|Vega:OTTMUSG00000062184 +100294714 Gm15983 MGI:MGI:3805549 +100301915 Gm16511 MGI:MGI:3848987 +100302110 Gm17808 MGI:MGI:5009994 +100302294 Ang-ps2 MGI:MGI:104985 +100302301 Gm17809 MGI:MGI:5009995 +100302374 Cyslter - +100302400 Gm14752 MGI:MGI:3705363 +100302432 Gm14435 MGI:MGI:3702420 +100302460 Rpl7a-ps13 MGI:MGI:3705484 +100302476 Lass1-gdf1 - +100302498 Snora21 MGI:MGI:3819493|Ensembl:ENSMUSG00000064901 +100302499 Snora3 MGI:MGI:3819498|Ensembl:ENSMUSG00000065016 +100302529 Snord72 MGI:MGI:3819555 +100302565 Snord68 MGI:MGI:3819550 +100302566 LOC100302566 - +100302567 AF357399 MGI:MGI:5439844 +100302576 Gm10243 MGI:MGI:3704266 +100302588 Gm14621 MGI:MGI:3705510 +100302592 Snord14a MGI:MGI:3851608|Ensembl:ENSMUSG00000064741 +100302593 Snord14d MGI:MGI:3851602|Ensembl:ENSMUSG00000095118 +100302594 Snord14e MGI:MGI:3851606|Ensembl:ENSMUSG00000064791 +100302595 Gm14780 MGI:MGI:3705499 +100302600 Snord43 MGI:MGI:3819534 +100302601 Snord83b MGI:MGI:3819557|Ensembl:ENSMUSG00000077734 +100302634 Astx6 MGI:MGI:3705134|Ensembl:ENSMUSG00000095005 +100302648 Gm11944 MGI:MGI:3702312|Ensembl:ENSMUSG00000084941 +100302649 Gm17811 MGI:MGI:5009996 +100302653 Gm17812 MGI:MGI:5009997 +100302654 Gm17813 MGI:MGI:5009998 +100302655 Gm14843 MGI:MGI:3802062 +100302687 Gm17814 MGI:MGI:5009999 +100302688 Gm17455 MGI:MGI:4937089|Ensembl:ENSMUSG00000090439 +100302730 5830417I10Rik MGI:MGI:1923272 +100302731 Snord7 MGI:MGI:3819552|Ensembl:ENSMUSG00000065715 +100303644 C130080G10Rik MGI:MGI:4844008|Ensembl:ENSMUSG00000092397 +100303645 D7Ertd143e MGI:MGI:1098629 +100303646 AF357355 MGI:MGI:3843217|Ensembl:ENSMUSG00000064621 +100303647 AF357359 MGI:MGI:3843219 +100303649 Gm11025 MGI:MGI:3779248 +100303729 E130009M23Rik MGI:MGI:3712488 +100303730 Gm16163 MGI:MGI:3833836 +100303731 Gm10874 MGI:MGI:3704261 +100303732 Zfp967 MGI:MGI:3709638|Ensembl:ENSMUSG00000095199 +100303733 Gm10501 MGI:MGI:3704476 +100303734 Gm9817 MGI:MGI:3809102 +100303735 7330403C04Rik MGI:MGI:3704475 +100303736 Snora35 MGI:MGI:3819503|Ensembl:ENSMUSG00000077767 +100303737 Gm11175 MGI:MGI:3809055 +100303738 D030025P21Rik MGI:MGI:3698049|Ensembl:ENSMUSG00000092130 +100303739 Gm10844 MGI:MGI:3704383 +100303740 Snora75 MGI:MGI:3819511|Ensembl:ENSMUSG00000064837 +100303741 Gm10308 MGI:MGI:3641943 +100303742 Gm9748 MGI:MGI:3642166 +100303744 Sprr2a2 MGI:MGI:3845026|Ensembl:ENSMUSG00000068893|Vega:OTTMUSG00000051828 +100303746 Snora20 MGI:MGI:3819492 +100303747 Gm12238 MGI:MGI:3651550|Ensembl:ENSMUSG00000065061|Ensembl:ENSMUSG00000087342 +100303751 Snora31 MGI:MGI:3819500|Ensembl:ENSMUSG00000065147 +100306874 B430218F22Rik MGI:MGI:3704413 +100306931 Gm13712 MGI:MGI:3650489 +100306934 Gm17815 MGI:MGI:5010000 +100306935 Gm14676 MGI:MGI:3705524 +100306943 Scarna13 MGI:MGI:4360027|Ensembl:ENSMUSG00000088789 +100306944 Snora73a MGI:MGI:4360046|Ensembl:ENSMUSG00000064387 +100306945 Snora73b MGI:MGI:4360049|Ensembl:ENSMUSG00000065353 +100306952 Snora78 MGI:MGI:4360056|Ensembl:ENSMUSG00000089255 +100306953 4122401K19Rik MGI:MGI:1921583 +100306954 Snora17 MGI:MGI:4360060|Ensembl:ENSMUSG00000077192 +100306955 Snora43 MGI:MGI:4360066|Ensembl:ENSMUSG00000064858|Ensembl:ENSMUSG00000097052 +100306957 Snora24 MGI:MGI:4360223|Ensembl:ENSMUSG00000092730 +100306959 B230322F03Rik MGI:MGI:3704291 +100306970 Gm17816 MGI:MGI:5010001 +100306977 Gm17082 MGI:MGI:4937909 +100307069 Gm17817 MGI:MGI:5010002 +100310753 A430073D23Rik MGI:MGI:4361019 +100310781 LOC100310781 - +100310787 1700016D18Rik MGI:MGI:1923668 +100310789 Gm17818 MGI:MGI:5010003 +100310809 Gm10509 MGI:MGI:3796835 +100310813 Snora16a MGI:MGI:4361141|Ensembl:ENSMUSG00000065097|Ensembl:ENSMUSG00000105911 +100310837 B930046C15Rik MGI:MGI:2441866 +100310868 Gm17819 MGI:MGI:5010004 +100310872 Dynlt1a MGI:MGI:3807506|Ensembl:ENSMUSG00000092074 +100310873 Gm9821 MGI:MGI:3704208 +100312470 Vmn1r2 MGI:MGI:4438400|Ensembl:ENSMUSG00000094798|Vega:OTTMUSG00000004179 +100312471 Vmn1r3 MGI:MGI:4438436|Ensembl:ENSMUSG00000095982|Vega:OTTMUSG00000004181 +100312472 Vmn1r-ps7 MGI:MGI:3852361 +100312473 Vmn1r86 MGI:MGI:4438438|Ensembl:ENSMUSG00000070816|Vega:OTTMUSG00000038213 +100312474 Vmn1r88 MGI:MGI:3852416|Ensembl:ENSMUSG00000095902|Vega:OTTMUSG00000038215 +100312475 Vmn1r95 MGI:MGI:3852449|Ensembl:ENSMUSG00000094735|Vega:OTTMUSG00000038187 +100312476 Vmn1r238 MGI:MGI:3852494|Ensembl:ENSMUSG00000091539|Vega:OTTMUSG00000039974 +100312477 Vmn1r184 MGI:MGI:3852451|Ensembl:ENSMUSG00000046130|Vega:OTTMUSG00000037987 +100312478 Vmn1r-ps39 MGI:MGI:3852377 +100312479 Vmn1r-ps40 MGI:MGI:3852380 +100312480 Vmn1r-ps41 MGI:MGI:3852381 +100312481 Vmn1r-ps42 MGI:MGI:3852382 +100312482 Vmn1r-ps44 MGI:MGI:3852384 +100312483 Vmn1r-ps45 MGI:MGI:3852386 +100312484 Vmn1r196 MGI:MGI:4438447|Ensembl:ENSMUSG00000069295|Vega:OTTMUSG00000000482 +100312485 Vmn1r221 MGI:MGI:4438449 +100312486 Vmn1r-ps13 MGI:MGI:3852363 +100312487 Vmn1r-ps16 MGI:MGI:3852364 +100312488 Vmn1r-ps21 MGI:MGI:3852365 +100312489 Vmn1r-ps23 MGI:MGI:3852366 +100312490 Vmn1r-ps29 MGI:MGI:3852367 +100312492 Vmn1r-ps31 MGI:MGI:3852370 +100312494 Vmn1r-ps35 MGI:MGI:3852371 +100312495 Vmn1r-ps36 MGI:MGI:3852372 +100312496 Vmn1r-ps49 MGI:MGI:3852387 +100312497 Vmn1r-ps50 MGI:MGI:3852388 +100312498 Vmn1r-ps51 MGI:MGI:3852391 +100312499 Vmn1r-ps52 MGI:MGI:3852396 +100312500 Vmn1r-ps54 MGI:MGI:3852397 +100312501 Vmn1r-ps55 MGI:MGI:3852398 +100312502 Vmn1r-ps56 MGI:MGI:3852399 +100312503 Vmn1r-ps57 MGI:MGI:3852400 +100312504 Vmn1r-ps58 MGI:MGI:3852401 +100312505 Vmn1r-ps59 MGI:MGI:3852402 +100312506 Vmn1r-ps60 MGI:MGI:3852403 +100312507 Vmn1r-ps61 MGI:MGI:3852404 +100312508 Vmn1r-ps62 MGI:MGI:3852405 +100312509 Vmn1r-ps63 MGI:MGI:4438458 +100312510 Vmn1r-ps64 MGI:MGI:3852407 +100312511 Vmn1r-ps66 MGI:MGI:3852408 +100312512 Vmn1r-ps67 MGI:MGI:3852412 +100312513 Vmn1r-ps68 MGI:MGI:3852413 +100312514 Vmn1r-ps69 MGI:MGI:3852419 +100312515 Vmn1r-ps86 MGI:MGI:3852450 +100312516 Vmn1r-ps87 MGI:MGI:3852452 +100312517 Vmn1r-ps137 MGI:MGI:3852472 +100312518 Vmn1r-ps138 MGI:MGI:3852475 +100312519 Vmn1r-ps151 MGI:MGI:3852490 +100312520 Vmn1r-ps152 MGI:MGI:3852491 +100312521 Vmn1r-ps89 - +100312522 Vmn1r-ps92 MGI:MGI:4439036 +100312523 Vmn1r-ps93 MGI:MGI:4439038 +100312524 Vmn1r-ps94 MGI:MGI:4439040 +100312525 Vmn1r-ps95 MGI:MGI:4439042 +100312526 Vmn1r-ps96 MGI:MGI:3852506 +100312527 Vmn1r-ps97 MGI:MGI:4439044 +100312528 Vmn1r-ps98 MGI:MGI:3852453 +100312529 Vmn1r-ps99 MGI:MGI:4439048 +100312530 Vmn1r-ps37 MGI:MGI:3852373 +100312531 Vmn1r-ps38 MGI:MGI:3852375 +100312532 Vmn1r-ps100 MGI:MGI:4439051 +100312533 Vmn1r-ps101 MGI:MGI:3852454 +100312534 Vmn1r-ps102 MGI:MGI:4439057 +100312535 Vmn1r-ps104 MGI:MGI:4439058 +100312536 Vmn1r-ps107 MGI:MGI:4439059 +100312537 Vmn1r-ps108 MGI:MGI:4439060 +100312538 Vmn1r-ps109 MGI:MGI:4439061 +100312539 Vmn1r-ps110 MGI:MGI:4439062 +100312540 Vmn1r-ps111 MGI:MGI:4439063 +100312541 Vmn1r-ps112 MGI:MGI:4439064 +100312542 Vmn1r-ps113 MGI:MGI:4439065 +100312543 Vmn1r-ps114 MGI:MGI:4439066 +100312544 Vmn1r-ps115 MGI:MGI:3852455 +100312545 Vmn1r-ps116 MGI:MGI:4439067 +100312546 Vmn1r-ps117 MGI:MGI:3852456 +100312547 Gm11320 MGI:MGI:3650584 +100312548 Gm11321 MGI:MGI:3651028 +100312549 Vmn1r-ps120 MGI:MGI:4439068 +100312550 Gm11322 MGI:MGI:3650586 +100312552 Vmn1r-ps123 MGI:MGI:4439075 +100312553 Vmn1r-ps124 MGI:MGI:3852458 +100312554 Vmn1r-ps125 MGI:MGI:4439076 +100312555 Vmn1r-ps126 MGI:MGI:4439077 +100312556 Vmn1r-ps127 MGI:MGI:4439078 +100312557 Vmn1r-ps129 MGI:MGI:3852461 +100312558 Vmn1r-ps130 MGI:MGI:3852462 +100312559 Vmn1r-ps131 MGI:MGI:3852468 +100312560 Vmn1r-ps132 MGI:MGI:4439079 +100312561 Vmn1r-ps133 MGI:MGI:3852469 +100312562 Vmn1r-ps134 MGI:MGI:3852470 +100312563 Vmn1r-ps135 MGI:MGI:4439317 +100312564 Vmn1r-ps136 MGI:MGI:3852471 +100312565 Vmn1r-ps139 MGI:MGI:3852479 +100312566 Vmn1r-ps140 MGI:MGI:3852480 +100312567 Vmn1r-ps141 MGI:MGI:3852481 +100312568 Vmn1r-ps142 MGI:MGI:3852482 +100312569 Vmn1r-ps143 MGI:MGI:3852483 +100312570 Vmn1r-ps145 MGI:MGI:3852484 +100312571 Vmn1r-ps146 MGI:MGI:3852486 +100312572 Vmn1r-ps147 MGI:MGI:3852487 +100312573 Vmn1r-ps148 MGI:MGI:3852488 +100312574 Vmn1r-ps149 MGI:MGI:3852489 +100312575 Vmn1r-ps150 MGI:MGI:4439321 +100312576 Vmn1r-ps91 - +100312577 Vmn1r-ps106 MGI:MGI:4439328 +100312946 Vmn1r-ps90 - +100312948 Gm17689 MGI:MGI:4937323|Ensembl:ENSMUSG00000091248|Vega:OTTMUSG00000044743 +100312949 Gm17677 MGI:MGI:4937311|Ensembl:ENSMUSG00000091174|Vega:OTTMUSG00000044683 +100312956 Pate3 MGI:MGI:4936999|Ensembl:ENSMUSG00000094995|Vega:OTTMUSG00000044701 +100312986 Gm17727 MGI:MGI:4937361|Ensembl:ENSMUSG00000090738|Vega:OTTMUSG00000044684 +100312987 Pate1 MGI:MGI:4936886|Ensembl:ENSMUSG00000091215|Vega:OTTMUSG00000044702 +100313510 C530020B09Rik MGI:MGI:3698878 +100313511 Gm10306 MGI:MGI:3704234 +100313512 E330011M16Rik MGI:MGI:3704186 +100313514 Gm9757 MGI:MGI:3704346 +100313518 Gm9868 MGI:MGI:3704309 +100313519 Snord17 MGI:MGI:3819523|Ensembl:ENSMUSG00000077714 +100313531 Nkx2-2os MGI:MGI:3652259|Ensembl:ENSMUSG00000086509 +100313943 Snora26 MGI:MGI:3819495|Ensembl:ENSMUSG00000093355 +100313944 Gm10645 MGI:MGI:3704313 +100313945 Gm14866 MGI:MGI:3704514 +100315604 Gm10401 MGI:MGI:3704254 +100315693 D630036H23Rik MGI:MGI:3704386 +100316663 Mir669k MGI:MGI:3783389|Ensembl:ENSMUSG00000094297|miRBase:MI0006279 +100316664 Mir669d MGI:MGI:3783382|Ensembl:ENSMUSG00000077834|miRBase:MI0006281 +100316665 Mir466i MGI:MGI:3783375|Ensembl:ENSMUSG00000080574|miRBase:MI0006282 +100316667 Mir669f MGI:MGI:3783384|Ensembl:ENSMUSG00000077038|miRBase:MI0006287 +100316668 Mir669i MGI:MGI:3783387|Ensembl:ENSMUSG00000080657|miRBase:MI0006288 +100316669 Mir1188 MGI:MGI:3783362|Ensembl:ENSMUSG00000080406|miRBase:MI0006290 +100316670 Mir466k MGI:MGI:3783377|Ensembl:ENSMUSG00000080424|miRBase:MI0006292 +100316671 Mir466j MGI:MGI:3783376|Ensembl:ENSMUSG00000080526|miRBase:MI0006295 +100316672 Mir1192 MGI:MGI:3783365|Ensembl:ENSMUSG00000080626|miRBase:MI0006297 +100316673 Mir1193 MGI:MGI:3783366|Ensembl:ENSMUSG00000080411|miRBase:MI0006298 +100316674 Mir467g MGI:MGI:3783380|Ensembl:ENSMUSG00000080556|miRBase:MI0006301 +100316675 Mir467h MGI:MGI:3783381|Ensembl:ENSMUSG00000080409|miRBase:MI0006302 +100316676 Mir1195 MGI:MGI:3783368|Ensembl:ENSMUSG00000080468|miRBase:MI0006303 +100316677 Mir1199 MGI:MGI:3783372|Ensembl:ENSMUSG00000080665|miRBase:MI0006307 +100316678 Mir1902 MGI:MGI:3811405|Ensembl:ENSMUSG00000084516|miRBase:MI0008313 +100316679 Mir1897 MGI:MGI:3811407|Ensembl:ENSMUSG00000104797|miRBase:MI0008314 +100316680 Mir1903 MGI:MGI:3811412|Ensembl:ENSMUSG00000084523|miRBase:MI0008317 +100316681 Mir1900 MGI:MGI:3811415|Ensembl:ENSMUSG00000084663|miRBase:MI0008319 +100316682 Mir1892 MGI:MGI:3811416|Ensembl:ENSMUSG00000106344|miRBase:MI0008320 +100316683 Mir1904 MGI:MGI:3811419|Ensembl:ENSMUSG00000084651|miRBase:MI0008323 +100316684 Mir1898 MGI:MGI:3811421|Ensembl:ENSMUSG00000084592|miRBase:MI0008324 +100316685 Mir1907 MGI:MGI:3811422|Ensembl:ENSMUSG00000084458|miRBase:MI0008325 +100316686 Mir1901 MGI:MGI:3811425|Ensembl:ENSMUSG00000084565|miRBase:MI0008328 +100316687 Mir1928 MGI:MGI:3836960|Ensembl:ENSMUSG00000087820|miRBase:MI0009917 +100316688 Mir1929 MGI:MGI:3836961|Ensembl:ENSMUSG00000089260|miRBase:MI0009918 +100316689 Mir1931 MGI:MGI:3836967|Ensembl:ENSMUSG00000089214|miRBase:MI0009920 +100316690 Mir1932 MGI:MGI:3836969|Ensembl:ENSMUSG00000088015|miRBase:MI0009921 +100316693 Mir1938 MGI:MGI:3836976|Ensembl:ENSMUSG00000089371|miRBase:MI0009927 +100316694 Mir1941 MGI:MGI:3836979|Ensembl:ENSMUSG00000088459|miRBase:MI0009930 +100316695 Mir1943 MGI:MGI:3836982|Ensembl:ENSMUSG00000088901|miRBase:MI0009932 +100316697 Mir1946a MGI:MGI:3837017|Ensembl:ENSMUSG00000088985|miRBase:MI0009936 +100316698 Mir1947 MGI:MGI:3837018|Ensembl:ENSMUSG00000088860|miRBase:MI0009937 +100316699 Mir1948 MGI:MGI:3837020|Ensembl:ENSMUSG00000087950|miRBase:MI0009939 +100316700 Mir1949 MGI:MGI:3837022|Ensembl:ENSMUSG00000105743|miRBase:MI0009940 +100316701 Mir669m-1 MGI:MGI:3837026|Ensembl:ENSMUSG00000089570|miRBase:MI0009943 +100316702 Mir669o MGI:MGI:3837028|Ensembl:ENSMUSG00000077086|miRBase:MI0009945 +100316703 Mir1951 MGI:MGI:3837029|Ensembl:ENSMUSG00000088606|miRBase:MI0009946 +100316704 Mir1953 MGI:MGI:3837034|Ensembl:ENSMUSG00000088491|miRBase:MI0009948 +100316705 Mir669n MGI:MGI:3837039|Ensembl:ENSMUSG00000089261|miRBase:MI0009951 +100316706 Mir1956 MGI:MGI:3837040|Ensembl:ENSMUSG00000088373|miRBase:MI0009952 +100316707 Mir1957a MGI:MGI:3837121|Ensembl:ENSMUSG00000088552|miRBase:MI0009954 +100316708 Mir1958 MGI:MGI:3837123|Ensembl:ENSMUSG00000087844|miRBase:MI0009955 +100316709 Mir1960 MGI:MGI:3837202|Ensembl:ENSMUSG00000088113|miRBase:MI0009957 +100316710 Mir1963 MGI:MGI:3837208|Ensembl:ENSMUSG00000089219|miRBase:MI0009960 +100316711 Mir1964 MGI:MGI:3837209|Ensembl:ENSMUSG00000089139|miRBase:MI0009961 +100316712 Mir1966 MGI:MGI:3837211|Ensembl:ENSMUSG00000089432|miRBase:MI0009963 +100316713 Mir1968 MGI:MGI:3837215|Ensembl:ENSMUSG00000088054|miRBase:MI0009965 +100316714 Mir1946b MGI:MGI:3837217|Ensembl:ENSMUSG00000088478|miRBase:MI0009967 +100316715 Mir1971 MGI:MGI:3837219|Ensembl:ENSMUSG00000087932|miRBase:MI0009970 +100316716 Mir1983 MGI:MGI:3837223|Ensembl:ENSMUSG00000088148|miRBase:MI0009990 +100316717 Mir1839 MGI:MGI:3837345|Ensembl:ENSMUSG00000104618|miRBase:MI0009991 +100316725 Mir2136 MGI:MGI:4358922|Ensembl:ENSMUSG00000089406|miRBase:MI0010749 +100316727 Mir2139 MGI:MGI:4358926|Ensembl:ENSMUSG00000089294|miRBase:MI0010752 +100316734 Mir2183 MGI:MGI:4358943|miRBase:MI0010833 +100316735 Mir432 MGI:MGI:4358944|Ensembl:ENSMUSG00000087855|miRBase:MI0012528 +100316736 Mir599 MGI:MGI:4358945|Ensembl:ENSMUSG00000076333|miRBase:MI0012529 +100316737 Mir664 MGI:MGI:4358947|Ensembl:ENSMUSG00000105770|miRBase:MI0012531 +100316739 Mir1224 MGI:MGI:3764925|Ensembl:ENSMUSG00000080669|miRBase:MI0004118 +100316749 Mir467f MGI:MGI:3783379|Ensembl:ENSMUSG00000080573|miRBase:MI0006293 +100316750 Mir1194 MGI:MGI:3783367|miRBase:MI0006299 +100316751 Mir1197 MGI:MGI:3783370|Ensembl:ENSMUSG00000080687|miRBase:MI0006305 +100316752 Mir1896 MGI:MGI:3811418|Ensembl:ENSMUSG00000084590|miRBase:MI0008322 +100316753 Mir1933 MGI:MGI:3836970|Ensembl:ENSMUSG00000089555|miRBase:MI0009922 +100316756 Mir1955 MGI:MGI:3837036|Ensembl:ENSMUSG00000088639|miRBase:MI0009950 +100316769 Mir466l MGI:MGI:3783378|Ensembl:ENSMUSG00000078060|miRBase:MI0006278 +100316770 Mir669j MGI:MGI:3783388|Ensembl:ENSMUSG00000095340|miRBase:MI0006286 +100316772 Mir1899 MGI:MGI:3811414|Ensembl:ENSMUSG00000084747|miRBase:MI0008318 +100316773 Mir1893 MGI:MGI:3811424|Ensembl:ENSMUSG00000084514|miRBase:MI0008327 +100316774 Mir1942 MGI:MGI:3836981|Ensembl:ENSMUSG00000087899|miRBase:MI0009931 +100316775 Mir1950 MGI:MGI:3837023|Ensembl:ENSMUSG00000089151|miRBase:MI0009941 +100316776 Mir1954 MGI:MGI:3837035|Ensembl:ENSMUSG00000093336|miRBase:MI0009949 +100316777 Mir1969 MGI:MGI:3837216|Ensembl:ENSMUSG00000088248|miRBase:MI0009966 +100316778 Mir1982 MGI:MGI:3837227|Ensembl:ENSMUSG00000087993|miRBase:MI0009993 +100316779 Mir2137 MGI:MGI:4358923|Ensembl:ENSMUSG00000089357|miRBase:MI0010750 +100316783 Mir1b MGI:MGI:3783373|Ensembl:ENSMUSG00000080662|miRBase:MI0006283 +100316784 Mir1927 MGI:MGI:3836959|Ensembl:ENSMUSG00000089204|miRBase:MI0009914 +100316802 Mir669g MGI:MGI:3783385|Ensembl:ENSMUSG00000080459|miRBase:MI0006280 +100316803 Mir1187 MGI:MGI:3783361|Ensembl:ENSMUSG00000080586|miRBase:MI0006285 +100316804 Mir466f-4 MGI:MGI:3783374|Ensembl:ENSMUSG00000080580|miRBase:MI0006291 +100316805 Mir1190 MGI:MGI:3783363|Ensembl:ENSMUSG00000080575|miRBase:MI0006294 +100316806 Mir669e MGI:MGI:3783383|Ensembl:ENSMUSG00000080653|miRBase:MI0006300 +100316807 Mir1198 MGI:MGI:3783371|Ensembl:ENSMUSG00000080645|miRBase:MI0006306 +100316808 Mir1905 MGI:MGI:3811408|Ensembl:ENSMUSG00000084728|miRBase:MI0008315 +100316809 Mir1906-1 MGI:MGI:3811417|Ensembl:ENSMUSG00000084535|miRBase:MI0008321 +100316810 Mir1894 MGI:MGI:3811423|Ensembl:ENSMUSG00000084751|miRBase:MI0008326 +100316811 Mir1930 MGI:MGI:3836965|Ensembl:ENSMUSG00000089424|miRBase:MI0009919 +100316812 Mir1936 MGI:MGI:3836973|Ensembl:ENSMUSG00000089324|miRBase:MI0009925 +100316814 Mir1306 MGI:MGI:3836985|Ensembl:ENSMUSG00000080452|miRBase:MI0009935 +100316815 Mir669l MGI:MGI:3837025|Ensembl:ENSMUSG00000076959|miRBase:MI0009942 +100316816 Mir1952 MGI:MGI:3837030|Ensembl:ENSMUSG00000088983|miRBase:MI0009947 +100316818 Mir1962 MGI:MGI:3837207|Ensembl:ENSMUSG00000088141|miRBase:MI0009959 +100316819 Mir1967 MGI:MGI:3837213|Ensembl:ENSMUSG00000088414|miRBase:MI0009964 +100316820 Mir1970 MGI:MGI:3837218|Ensembl:ENSMUSG00000088464|miRBase:MI0009968 +100316821 Mir1981 MGI:MGI:3837225|Ensembl:ENSMUSG00000088559|miRBase:MI0009992 +100316827 Mir767 MGI:MGI:4358946|Ensembl:ENSMUSG00000076455|miRBase:MI0012530 +100316831 Mir669h MGI:MGI:3783386|Ensembl:ENSMUSG00000080594|miRBase:MI0006289 +100316832 Mir1895 MGI:MGI:3811410|Ensembl:ENSMUSG00000084564|miRBase:MI0008316 +100316833 Mir1945 MGI:MGI:3836984|Ensembl:ENSMUSG00000088544|miRBase:MI0009934 +100316834 Mir669m-2 MGI:MGI:3837027|Ensembl:ENSMUSG00000088980|miRBase:MI0009944 +100316839 Mir1191 MGI:MGI:3783364|Ensembl:ENSMUSG00000080533|miRBase:MI0006296 +100316840 Mir1934 MGI:MGI:3836971|Ensembl:ENSMUSG00000088752|miRBase:MI0009923 +100316841 Mir1961 MGI:MGI:3837206|Ensembl:ENSMUSG00000089268|miRBase:MI0009958 +100316846 Gm10367 MGI:MGI:3704923 +100316865 Gm10931 MGI:MGI:3779142 +100316869 Gm17820 MGI:MGI:5010005 +100316870 Gm17821 MGI:MGI:5010006 +100316903 Gm20605 MGI:MGI:5306917 +100316932 Snora28 MGI:MGI:3819496|Ensembl:ENSMUSG00000064493 +100322896 Dthd1 MGI:MGI:4937018|Ensembl:ENSMUSG00000090326|Vega:OTTMUSG00000055091 +100327264 C130013H08Rik MGI:MGI:3697343 +100327266 9430064I24Rik MGI:MGI:3704302 +100328567 Gm17822 MGI:MGI:5010007 +100328574 Proscos MGI:MGI:3704307 +100328588 Gm21948 MGI:MGI:5439399|Ensembl:ENSMUSG00000074141|Vega:OTTMUSG00000029474 +100328601 Gm13355 MGI:MGI:3650085 +100329138 Gm3699 MGI:MGI:3781875 +100329140 Mettl5os MGI:MGI:1922537 +100359411 Gm9798 MGI:MGI:3704497 +100359413 AA413626 MGI:MGI:3035311|Ensembl:ENSMUSG00000084381 +100379095 A830092H15Rik MGI:MGI:3698881 +100379127 Gm16491 MGI:MGI:3704371 +100379129 Gm10353 MGI:MGI:3704491 +100379143 Gm9754 MGI:MGI:3704256 +100379144 A330079N23Rik MGI:MGI:3604301 +100379145 Snora23 MGI:MGI:3819494|Ensembl:ENSMUSG00000064451 +100379146 Gm10642 MGI:MGI:3704338 +100379214 Gm16533 MGI:MGI:4410373 +100379258 Gm9963 MGI:MGI:3704337 +100379259 Gm10300 MGI:MGI:3641670 +100379292 Gm10430 MGI:MGI:3711274 +100379603 Gm13583 MGI:MGI:3650462 +100379604 Gm13872 MGI:MGI:3650731 +100379605 Gm15270 MGI:MGI:3705149 +100379606 Gm15247 MGI:MGI:3705183 +100379607 Gm10997 MGI:MGI:3779213 +100379608 Gm15622 MGI:MGI:3783067 +100379609 Gm12606 MGI:MGI:3649222 +100379610 Gm11651 MGI:MGI:3651203|Ensembl:ENSMUSG00000085297 +100379611 Gm11767 MGI:MGI:3650674 +100379612 Gm15886 MGI:MGI:3801744 +100379660 Gm9806 MGI:MGI:3708646 +100379665 9330121J05Rik MGI:MGI:3704218 +100380944 Ino80dos MGI:MGI:3651861|Ensembl:ENSMUSG00000084799 +100381209 Gm17823 MGI:MGI:5010008 +100381255 BC026863 MGI:MGI:4437735 +100381256 A330027G23Rik MGI:MGI:4437737 +100381257 Gm12100 MGI:MGI:3651586 +100381258 D930001M23Rik MGI:MGI:4437791 +100384868 Gm37013 MGI:MGI:5610241|Ensembl:ENSMUSG00000103458|Vega:OTTMUSG00000050657 +100384870 Gm11257 MGI:MGI:3649985 +100384871 Gm12630 MGI:MGI:3650968 +100384872 Gm13039 MGI:MGI:3649997 +100384873 Gm11760 MGI:MGI:3651479 +100384874 Gm17824 MGI:MGI:5010009 +100384876 Gm15617 MGI:MGI:3783062 +100384877 Gm13864 MGI:MGI:3651491 +100384878 Gm17825 MGI:MGI:5010010 +100384879 Gm17826 MGI:MGI:5010011 +100384880 Gm17827 MGI:MGI:5010012 +100384881 Gm16071 MGI:MGI:3801777 +100384882 Gm17828 MGI:MGI:5010013 +100384883 Gm16166 MGI:MGI:3801807 +100384890 D230030E09Rik MGI:MGI:4438394|Ensembl:ENSMUSG00000113875 +100384904 Gm20583 MGI:MGI:5295689 +100384905 Gm20584 MGI:MGI:5295690 +100415768 Gm15304 MGI:MGI:3705536 +100415769 Gm15302 MGI:MGI:3705638 +100415770 Gm7869 MGI:MGI:3644630 +100415779 Gm17829 MGI:MGI:5010014 +100415784 Gm17830 MGI:MGI:5010015 +100415785 Gm11559 MGI:MGI:3652067|Ensembl:ENSMUSG00000090225|Vega:OTTMUSG00000002191 +100415786 Gm13783 MGI:MGI:3649551 +100415787 Tomm6os MGI:MGI:3705171|Ensembl:ENSMUSG00000084880 +100415813 Gm17831 MGI:MGI:5010016 +100415898 Gm20945 MGI:MGI:5434300 +100415900 Gm20946 MGI:MGI:5434301 +100415901 Gm13648 MGI:MGI:3652033|Ensembl:ENSMUSG00000086549 +100415902 Gm15658 MGI:MGI:3783101 +100415912 Gm11665 MGI:MGI:3650128 +100415913 Gm14123 MGI:MGI:3650509 +100415914 Gm12505 MGI:MGI:3651173|Ensembl:ENSMUSG00000087070 +100415915 A530072M11Rik MGI:MGI:4440477|Ensembl:ENSMUSG00000085112 +100415916 Gm15997 MGI:MGI:3805557|Ensembl:ENSMUSG00000107132 +100415919 Gm12795 MGI:MGI:3649205 +100415920 Gm12304 MGI:MGI:3651803 +100415944 LOC100415944 - +100415946 Gm17832 MGI:MGI:5010017 +100415947 Gm14021 MGI:MGI:3651447 +100415948 Gm17833 MGI:MGI:5010018 +100415951 Gm17834 MGI:MGI:5010019 +100415952 Gm17835 MGI:MGI:5010020 +100415953 Gm17836 MGI:MGI:5010021 +100415954 Gm14741 MGI:MGI:3705423 +100415955 Gm14940 MGI:MGI:3705334 +100415956 Gm17837 MGI:MGI:5010022 +100415957 Gm17838 MGI:MGI:5010023 +100415958 Ywhaq-ps1 MGI:MGI:5010024 +100415959 Gm17840 MGI:MGI:5010025 +100415960 Gm17841 MGI:MGI:5010026 +100415961 Gm6659 MGI:MGI:3648914 +100415963 Gm12856 MGI:MGI:3649664 +100415967 Gm17842 MGI:MGI:5010027 +100415968 Gm17843 MGI:MGI:5010028 +100415969 Gm17844 MGI:MGI:5010029 +100415971 Gm14857 MGI:MGI:3716318 +100415972 Gm14834 MGI:MGI:3801979 +100415973 Gm17845 MGI:MGI:5010030 +100415974 Gm15078 MGI:MGI:3705413 +100415975 Gm17846 MGI:MGI:5010031 +100415976 Gm17847 MGI:MGI:5010032 +100415977 Gm17848 MGI:MGI:5010033 +100415978 Gm17849 MGI:MGI:5010034 +100415979 Gm17850 MGI:MGI:5010035 +100415980 Gm17851 MGI:MGI:5010036 +100415981 Gm17852 MGI:MGI:5010037 +100415982 Gm17853 MGI:MGI:5010038 +100415983 Gm14357 MGI:MGI:3650963 +100415984 Gm17854 MGI:MGI:5010039 +100415985 Gm15260 MGI:MGI:3705373 +100415986 Gm17855 MGI:MGI:5010040 +100415987 Gm17856 MGI:MGI:5010041 +100415988 Gm15273 MGI:MGI:3826550 +100415989 Gm17857 MGI:MGI:5010042 +100415990 Gm17858 MGI:MGI:5010043 +100415991 Gm17859 MGI:MGI:5010044 +100415992 Gm14610 MGI:MGI:3705700 +100415993 LOC100415993 - +100415994 Gm14361 MGI:MGI:3650344 +100415995 Gm15257 MGI:MGI:3826568 +100415996 Gm14356 MGI:MGI:3650964 +100415997 Gm14348 MGI:MGI:3650761 +100415998 Gm15256 MGI:MGI:3782932 +100415999 Gm15252 MGI:MGI:3826575 +100416000 Gm17860 MGI:MGI:5010045 +100416001 Gm17861 MGI:MGI:5010046 +100416002 Gm17862 MGI:MGI:5010047 +100416003 Gm17863 MGI:MGI:5010048 +100416004 Gm17864 MGI:MGI:5010049 +100416005 Gm17865 MGI:MGI:5010050 +100416006 Gm17866 MGI:MGI:5010051 +100416007 Gm17867 MGI:MGI:5010052 +100416009 Gm17868 MGI:MGI:5010053 +100416010 Gm17869 MGI:MGI:5010054 +100416011 Gm15666 MGI:MGI:3783108 +100416012 Gm17870 MGI:MGI:5010055 +100416013 Gm17871 MGI:MGI:5010056 +100416014 Gm17872 MGI:MGI:5010057 +100416017 Gm17873 MGI:MGI:5010058 +100416019 Gm17874 MGI:MGI:5010059 +100416021 Gm17235 MGI:MGI:4938062 +100416022 Gm17875 MGI:MGI:5010060 +100416023 Cnn2-ps MGI:MGI:5010061 +100416024 Gm17877 MGI:MGI:5010062 +100416027 Gm17878 MGI:MGI:5010063 +100416030 Gm17879 MGI:MGI:5010064 +100416031 Gm17880 MGI:MGI:5010065 +100416032 Gm17087 MGI:MGI:4937914 +100416033 Gm17881 MGI:MGI:5010066 +100416034 Gm17882 MGI:MGI:5010067 +100416036 Gm17883 MGI:MGI:5010068 +100416038 Gm17884 MGI:MGI:5010069 +100416039 Gm17885 MGI:MGI:5010070 +100416041 Gm17887 MGI:MGI:5010072 +100416042 Gm13689 MGI:MGI:3652061 +100416043 Gm17888 MGI:MGI:5010073 +100416044 Gm17889 MGI:MGI:5010074 +100416045 Gm17890 MGI:MGI:5010075 +100416046 Gm17891 MGI:MGI:5010076 +100416047 Gm17892 MGI:MGI:5010077 +100416048 Gm11653 MGI:MGI:3651873 +100416050 Gm38395 MGI:MGI:5618687 +100416051 Gm13719 MGI:MGI:3649492 +100416052 Gm13435 MGI:MGI:3650576 +100416053 Gm17893 MGI:MGI:5010078 +100416054 Gm15693 MGI:MGI:3783134 +100416055 Gm21925 MGI:MGI:5439377 +100416056 Gm12997 MGI:MGI:3650026 +100416057 Gm17894 MGI:MGI:5010079 +100416058 Gm17895 MGI:MGI:5010080 +100416059 Gm17896 MGI:MGI:5010081 +100416060 Gm12583 MGI:MGI:3651485 +100416061 Gm17897 MGI:MGI:5010082 +100416062 Gm13423 MGI:MGI:3650165 +100416063 Gm17898 MGI:MGI:5010083 +100416064 Gm13673 MGI:MGI:3650280 +100416065 Gm17899 MGI:MGI:5010084 +100416066 Gm17900 MGI:MGI:5010085 +100416067 Gm17901 MGI:MGI:5010086 +100416068 Gm14776 MGI:MGI:3705559 +100416069 Gm17902 MGI:MGI:5010087 +100416070 Gm15901 MGI:MGI:3802080 +100416072 Gm17903 MGI:MGI:5010088 +100416073 Gm17904 MGI:MGI:5010089 +100416074 Gm17905 MGI:MGI:5010090 +100416075 Gm17906 MGI:MGI:5010091 +100416076 Gm17907 MGI:MGI:5010092 +100416077 Gm17908 MGI:MGI:5010093 +100416078 Gm17909 MGI:MGI:5010094 +100416079 Gm2448 MGI:MGI:3780615 +100416080 Gm17910 MGI:MGI:5010095 +100416081 Gm17911 MGI:MGI:5010096 +100416084 Gm17912 MGI:MGI:5010097 +100416085 Gm11905 MGI:MGI:3650369 +100416086 Gm12363 MGI:MGI:3652293 +100416087 Gm12543 MGI:MGI:3649591 +100416089 Gm17060 MGI:MGI:4937887 +100416091 Gm16202 MGI:MGI:3802152 +100416093 Gm17075 MGI:MGI:4937902 +100416094 Gm17913 MGI:MGI:5010098 +100416095 Gm15808 MGI:MGI:3802045 +100416096 Gm14806 MGI:MGI:3802100 +100416097 Gm15193 MGI:MGI:3705583 +100416098 Gm14575 MGI:MGI:3705670 +100416100 Gm17914 MGI:MGI:5010099 +100416101 Gm17915 MGI:MGI:5010100 +100416102 Gm17916 MGI:MGI:5010101 +100416104 Gm17917 MGI:MGI:5010102 +100416105 Gm16270 MGI:MGI:3841260 +100416106 Gm17918 MGI:MGI:5010103 +100416107 Gm17919 MGI:MGI:5010104 +100416108 Gm15974 MGI:MGI:3801981 +100416109 Gm17920 MGI:MGI:5010105 +100416110 Gm17921 MGI:MGI:5010106 +100416111 Gm17922 MGI:MGI:5010107 +100416112 Gm15916 MGI:MGI:3801989 +100416113 Gm15765 MGI:MGI:3783207 +100416114 Gm17923 MGI:MGI:5010108 +100416115 Prdx1-ps MGI:MGI:5010109 +100416116 Gm11560 MGI:MGI:3652066 +100416117 Gm17925 MGI:MGI:5010110 +100416118 Gm16165 MGI:MGI:3802009 +100416119 Gm17926 MGI:MGI:5010111 +100416120 Gm17927 MGI:MGI:5010112 +100416121 Gm15950 MGI:MGI:3802178 +100416122 Gm17928 MGI:MGI:5010113 +100416123 Gm14746 MGI:MGI:3705706 +100416125 Gm14895 MGI:MGI:3708101 +100416126 Gm17929 MGI:MGI:5010114 +100416127 Gm17229 MGI:MGI:4938056 +100416128 Gm17930 MGI:MGI:5010115 +100416129 Gm17931 MGI:MGI:5010116 +100416130 Gm17932 MGI:MGI:5010117 +100416131 Gm12156 MGI:MGI:3649752 +100416132 Gm11873 MGI:MGI:3649334 +100416135 Gm17933 MGI:MGI:5010118 +100416136 Gm17934 MGI:MGI:5010119 +100416137 Gm17935 MGI:MGI:5010120 +100416138 Gm17936 MGI:MGI:5010121 +100416139 Gm17937 MGI:MGI:5010122 +100416142 Gm17938 MGI:MGI:5010123 +100416143 Gm15599 MGI:MGI:3783046 +100416144 Gm17939 MGI:MGI:5010124 +100416145 Tuba-rs1 MGI:MGI:1349435 +100416146 Gm17940 MGI:MGI:5010125 +100416147 Gm17941 MGI:MGI:5010126 +100416148 Gm17942 MGI:MGI:5010127 +100416149 Gm17943 MGI:MGI:5010128 +100416151 Gm12102 MGI:MGI:3651380 +100416153 Ifna-ps1 MGI:MGI:107669 +100416155 Gm17944 MGI:MGI:5010129 +100416156 Gm14554 MGI:MGI:3705880 +100416157 Gm17945 MGI:MGI:5010130 +100416158 Gm17946 MGI:MGI:5010131 +100416160 Wdr46-ps MGI:MGI:5010132 +100416161 Gm17948 MGI:MGI:5010133 +100416162 Gm17949 MGI:MGI:5010134 +100416164 Gm17950 MGI:MGI:5010135 +100416165 Gm17951 MGI:MGI:5010136 +100416166 Gm17952 MGI:MGI:5010137 +100416167 Gm17953 MGI:MGI:5010138 +100416168 Gm17954 MGI:MGI:5010139 +100416169 Gm17955 MGI:MGI:5010140 +100416170 Gm3040 MGI:MGI:3781218 +100416171 Gm17956 MGI:MGI:5010141 +100416172 Gm13426 MGI:MGI:3652100 +100416173 Gm13406 MGI:MGI:3649758 +100416174 Gm13495 MGI:MGI:3651036 +100416175 Gm13593 MGI:MGI:3650916 +100416176 Gm13739 MGI:MGI:3649857 +100416177 Gm17957 MGI:MGI:5010142 +100416178 Gm17958 MGI:MGI:5010143 +100416179 Gm14083 MGI:MGI:3650895 +100416180 Gm17959 MGI:MGI:5010144 +100416181 Gm14172 MGI:MGI:3650935 +100416183 Gm17961 MGI:MGI:5010146 +100416184 Gm13367 MGI:MGI:3651223 +100416185 Gm13378 MGI:MGI:3650302 +100416187 Gm14425 MGI:MGI:3652020 +100416188 Gm13818 MGI:MGI:3649322 +100416190 Gm14240 MGI:MGI:3650911 +100416191 Gm14562 MGI:MGI:3641982 +100416193 Gm17962 MGI:MGI:5010147 +100416194 Gm14987 MGI:MGI:3705432 +100416195 LOC100416195 - +100416196 Gm14600 MGI:MGI:3705546 +100416198 Gm17963 MGI:MGI:5010148 +100416199 Gm14975 MGI:MGI:3705512 +100416200 Gm15044 MGI:MGI:3705558 +100416201 Gm15159 MGI:MGI:3705490 +100416202 Gm15604 MGI:MGI:3783051 +100416203 Gm13751 MGI:MGI:3650600 +100416204 Gm16305 MGI:MGI:3826519 +100416205 Gm17964 MGI:MGI:5010149 +100416206 Gm17965 MGI:MGI:5010150 +100416207 Gm17966 MGI:MGI:5010151 +100416208 Gm17967 MGI:MGI:5010152 +100416209 Gm17968 MGI:MGI:5010153 +100416210 Gm17969 MGI:MGI:5010154 +100416211 Gm17970 MGI:MGI:5010155 +100416214 Gm17971 MGI:MGI:5010156 +100416215 Gm17972 MGI:MGI:5010157 +100416216 Gm17973 MGI:MGI:5010158 +100416217 Gm17974 MGI:MGI:5010159 +100416218 Gm17975 MGI:MGI:5010160 +100416219 Gm17976 MGI:MGI:5010161 +100416220 Gm16585 MGI:MGI:4415005 +100416221 Gm17977 MGI:MGI:5010162 +100416222 Gm17978 MGI:MGI:5010163 +100416223 Gm17979 MGI:MGI:5010164 +100416224 Gm17980 MGI:MGI:5010165 +100416225 Gm17981 MGI:MGI:5010166 +100416226 Gm17982 MGI:MGI:5010167 +100416227 Gm17983 MGI:MGI:5010168 +100416228 Gm17984 MGI:MGI:5010169 +100416229 Gm17985 MGI:MGI:5010170 +100416230 Gm17986 MGI:MGI:5010171 +100416231 Gm15877 MGI:MGI:3801978 +100416232 Gm17987 MGI:MGI:5010172 +100416233 Gm17988 MGI:MGI:5010173 +100416234 Gm17989 MGI:MGI:5010174 +100416235 Gm17990 MGI:MGI:5010175 +100416236 Gm17991 MGI:MGI:5010176 +100416237 Gm17992 MGI:MGI:5010177 +100416238 Gm17993 MGI:MGI:5010178 +100416239 Gm17994 MGI:MGI:5010179 +100416240 Gm17995 MGI:MGI:5010180 +100416241 Gm17996 MGI:MGI:5010181 +100416242 Gm17997 MGI:MGI:5010182 +100416243 Stambp-ps1 MGI:MGI:5010183 +100416244 Gm15549 MGI:MGI:3782998 +100416245 Gm17999 MGI:MGI:5010184 +100416246 Gm18000 MGI:MGI:5010185 +100416247 Gm18001 MGI:MGI:5010186 +100416248 Gm18002 MGI:MGI:5010187 +100416250 Gm18003 MGI:MGI:5010188 +100416251 Gm16300 MGI:MGI:3826587 +100416252 Gm11909 MGI:MGI:3650142 +100416253 Gm18004 MGI:MGI:5010189 +100416254 Gm18005 MGI:MGI:5010190 +100416255 LOC100416255 - +100416256 Gm12370 MGI:MGI:3652094 +100416257 Gm12383 MGI:MGI:3651852 +100416258 Gm12518 MGI:MGI:3652273 +100416259 Gm12654 MGI:MGI:3651710 +100416260 Gm13250 MGI:MGI:3650425 +100416261 Gm18006 MGI:MGI:5010191 +100416262 Gm13854 MGI:MGI:3651023 +100416263 Gm13859 MGI:MGI:3649465 +100416264 Gm18007 MGI:MGI:5010192 +100416266 Gm18008 MGI:MGI:5010193 +100416267 Gm18009 MGI:MGI:5010194 +100416268 Gm18010 MGI:MGI:5010195 +100416269 Gm18011 MGI:MGI:5010196 +100416270 Gm18012 MGI:MGI:5010197 +100416271 Gm15766 MGI:MGI:3783208 +100416272 Gm18013 MGI:MGI:5010198 +100416273 Gm18014 MGI:MGI:5010199 +100416274 Gm18015 MGI:MGI:5010200 +100416275 Gm18016 MGI:MGI:5010201 +100416276 Gm17040 MGI:MGI:4937867 +100416277 Gm16073 MGI:MGI:3802177 +100416278 Gm18017 MGI:MGI:5010202 +100416279 Gm17214 MGI:MGI:4938041 +100416280 Gm17212 MGI:MGI:4938039 +100416282 Gm18018 MGI:MGI:5010203 +100416283 Gm14441 MGI:MGI:3652321 +100416284 Gm13924 MGI:MGI:3651588 +100416285 Gm13477 MGI:MGI:3652109 +100416286 Gm13665 MGI:MGI:3651571 +100416287 Gm11475 MGI:MGI:3652278 +100416288 Gm18019 MGI:MGI:5010204 +100416289 Gm18020 MGI:MGI:5010205 +100416290 Gm15539 MGI:MGI:3782987 +100416291 Gm15712 MGI:MGI:3783154 +100416292 Gm18021 MGI:MGI:5010206 +100416293 Gm14615 MGI:MGI:3705656 +100416294 Gm14631 MGI:MGI:3705535 +100416295 Gm18022 MGI:MGI:5010207 +100416296 Gm14933 MGI:MGI:3802039 +100416297 Gm14913 MGI:MGI:3705431 +100416298 Gm18023 MGI:MGI:5010208 +100416299 Gm14518 MGI:MGI:3705455 +100416300 Gm14682 MGI:MGI:3705428 +100416301 Gm14716 MGI:MGI:3705736 +100416303 Gm15081 MGI:MGI:3705574 +100416305 Gm15096 MGI:MGI:3705752 +100416306 Gm18024 MGI:MGI:5010209 +100416307 Gm18025 MGI:MGI:5010210 +100416308 Gm18026 MGI:MGI:5010211 +100416309 Gm18027 MGI:MGI:5010212 +100416310 Gm18028 MGI:MGI:5010213 +100416311 Gm18029 MGI:MGI:5010214 +100416312 Gm18030 MGI:MGI:5010215 +100416313 Gm18031 MGI:MGI:5010216 +100416314 Gm18032 MGI:MGI:5010217 +100416315 Gm18033 MGI:MGI:5010218 +100416316 Gm18034 MGI:MGI:5010219 +100416317 Gm15843 MGI:MGI:3801845 +100416318 Gm18035 MGI:MGI:5010220 +100416319 Gm18036 MGI:MGI:5010221 +100416320 Gm18037 MGI:MGI:5010222 +100416321 Gm16111 MGI:MGI:3801919 +100416322 Gm18038 MGI:MGI:5010223 +100416323 Gm18039 MGI:MGI:5010224 +100416324 Gm18040 MGI:MGI:5010225 +100416325 Gm16148 MGI:MGI:3801829 +100416326 Gm18041 MGI:MGI:5010226 +100416327 Gm18042 MGI:MGI:5010227 +100416328 Gm16128 MGI:MGI:3801948 +100416329 Gm18043 MGI:MGI:5010228 +100416330 Ranbp2-ps2 MGI:MGI:5010229 +100416331 Api5-ps MGI:MGI:5010230 +100416332 Gm15570 MGI:MGI:3783018 +100416333 Gm18046 MGI:MGI:5010231 +100416334 Rpl15-ps5 MGI:MGI:5010232 +100416335 Phf20-ps MGI:MGI:5010233 +100416336 Gm16184 MGI:MGI:3802154 +100416337 Gm18049 MGI:MGI:5010234 +100416338 Gm18050 MGI:MGI:5010235 +100416340 Gm18052 MGI:MGI:5010237 +100416341 Gm18053 MGI:MGI:5010238 +100416342 Gm18054 MGI:MGI:5010239 +100416343 Gm18055 MGI:MGI:5010240 +100416344 Gm18056 MGI:MGI:5010241 +100416345 Gm18057 MGI:MGI:5010242 +100416346 Gm18058 MGI:MGI:5010243 +100416347 Gm18059 MGI:MGI:5010244 +100416348 Gm18060 MGI:MGI:5010245 +100416349 Gm18061 MGI:MGI:5010246 +100416350 Gm18062 MGI:MGI:5010247 +100416351 Gm18063 MGI:MGI:5010248 +100416353 Gm18064 MGI:MGI:5010249 +100416354 Gm18065 MGI:MGI:5010250 +100416355 Gm18066 MGI:MGI:5010251 +100416356 Gm15660 MGI:MGI:3783102 +100416357 Gm18067 MGI:MGI:5010252 +100416358 Gm18068 MGI:MGI:5010253 +100416360 LOC100416360 - +100416361 Gm18069 MGI:MGI:5010254 +100416362 Gm18070 MGI:MGI:5010255 +100416363 Gm18071 MGI:MGI:5010256 +100416364 Gm18072 MGI:MGI:5010257 +100416366 Gm18073 MGI:MGI:5010258 +100416368 Gm18074 MGI:MGI:5010259 +100416369 Gm18075 MGI:MGI:5010260 +100416370 Gm18076 MGI:MGI:5010261 +100416371 Gm18077 MGI:MGI:5010262 +100416372 Gm18078 MGI:MGI:5010263 +100416373 Gm18079 MGI:MGI:5010264 +100416374 Gm18080 MGI:MGI:5010265 +100416376 Gm18081 MGI:MGI:5010266 +100416377 Gm18082 MGI:MGI:5010267 +100416378 Gm18083 MGI:MGI:5010268 +100416379 Gm18084 MGI:MGI:5010269 +100416380 Gm18085 MGI:MGI:5010270 +100416381 Gm18086 MGI:MGI:5010271 +100416382 Gm18087 MGI:MGI:5010272 +100416383 Gm18088 MGI:MGI:5010273 +100416384 Gm18089 MGI:MGI:5010274 +100416385 Gm18090 MGI:MGI:5010275 +100416386 Siah1-ps2 MGI:MGI:108065 +100416387 Gm18092 MGI:MGI:5010277 +100416388 Gm15383 MGI:MGI:3707454 +100416389 Gm18093 MGI:MGI:5010278 +100416390 Gm18094 MGI:MGI:5010279 +100416391 Gm18095 MGI:MGI:5010280 +100416392 Gm12133 MGI:MGI:3651511 +100416393 Gm12149 MGI:MGI:3649952 +100416395 Gm11643 MGI:MGI:3652126 +100416397 Gm11416 MGI:MGI:3652028 +100416398 Gm11622 MGI:MGI:3650005 +100416399 Gm18096 MGI:MGI:5010281 +100416400 Gm11736 MGI:MGI:3650061 +100416401 Gm12477 MGI:MGI:3651220 +100416402 Gm12607 MGI:MGI:3649224 +100416403 Gm18097 MGI:MGI:5010282 +100416404 Gm18098 MGI:MGI:5010283 +100416405 Gm18099 MGI:MGI:5010284 +100416406 Gm18100 MGI:MGI:5010285 +100416409 Gm18101 MGI:MGI:5010286 +100416413 Gm18102 MGI:MGI:5010287 +100416414 Gm18103 MGI:MGI:5010288 +100416415 Gm18104 MGI:MGI:5010289 +100416427 Gm18105 MGI:MGI:5010290 +100416428 Gm18106 MGI:MGI:5010291 +100416430 Gm18107 MGI:MGI:5010292 +100416432 Gm14784 MGI:MGI:3705764 +100416433 Gm18108 MGI:MGI:5010293 +100416434 Gm18109 MGI:MGI:5010294 +100416435 Gm14783 MGI:MGI:3705346 +100416436 Gm18110 MGI:MGI:5010295 +100416437 Gm18111 MGI:MGI:5010296 +100416438 Gm14847 MGI:MGI:3801740 +100416439 Gm15061 MGI:MGI:3705543 +100416440 Gm18112 MGI:MGI:5010297 +100416441 Gm18113 MGI:MGI:5010298 +100416442 Gm15636 MGI:MGI:3783080 +100416443 Gm18114 MGI:MGI:5010299 +100416444 Gm18115 MGI:MGI:5010300 +100416445 Gm18116 MGI:MGI:5010301 +100416447 Gm18117 MGI:MGI:5010302 +100416454 Gm18118 MGI:MGI:5010303 +100416455 Gm16074 MGI:MGI:3801963 +100416456 Gm18119 MGI:MGI:5010304 +100416457 Gm18120 MGI:MGI:5010305 +100416458 Gm18121 MGI:MGI:5010306 +100416459 Gm18122 MGI:MGI:5010307 +100416460 Gm18123 MGI:MGI:5010308 +100416461 Gm18124 MGI:MGI:5010309 +100416462 Gm18125 MGI:MGI:5010310 +100416463 Gm18126 MGI:MGI:5010311 +100416464 Gm18127 MGI:MGI:5010312 +100416477 Gm3854 MGI:MGI:3782026 +100416478 Gm18128 MGI:MGI:5010313 +100416479 Gm18129 MGI:MGI:5010314 +100416501 Rpl17-ps6 MGI:MGI:5010315 +100416502 Gm18131 MGI:MGI:5010316 +100416503 Gm11343 MGI:MGI:3650912 +100416504 Gm18132 MGI:MGI:5010317 +100416505 Gm18133 MGI:MGI:5010318 +100416506 Gm18134 MGI:MGI:5010319 +100416507 Gm18135 MGI:MGI:5010320 +100416508 Gm18136 MGI:MGI:5010321 +100416509 Gm18137 MGI:MGI:5010322 +100416511 Gm15426 MGI:MGI:3705598 +100416514 Gm18138 MGI:MGI:5010323 +100416517 Gm18139 MGI:MGI:5010324 +100416518 Gm18140 MGI:MGI:5010325 +100416519 Gm18141 MGI:MGI:5010326 +100416520 Gm18142 MGI:MGI:5010327 +100416521 Gm16259 MGI:MGI:3826542 +100416522 Gm18143 MGI:MGI:5010328 +100416523 Gm18144 MGI:MGI:5010329 +100416526 Gm18145 MGI:MGI:5010330 +100416527 Gm18146 MGI:MGI:5010331 +100416528 Gm18147 MGI:MGI:5010332 +100416529 Gm18148 MGI:MGI:5010333 +100416530 Gm18149 MGI:MGI:5010334 +100416531 Gm18150 MGI:MGI:5010335 +100416532 Gm18151 MGI:MGI:5010336 +100416533 Gm18152 MGI:MGI:5010337 +100416534 Gm18153 MGI:MGI:5010338 +100416535 Gm18154 MGI:MGI:5010339 +100416536 Gm18155 MGI:MGI:5010340 +100416537 Gm12073 MGI:MGI:3650748 +100416541 Gm11500 MGI:MGI:3650688 +100416542 Gm18156 MGI:MGI:5010341 +100416544 Gm12192 MGI:MGI:3649287 +100416550 Gm11422 MGI:MGI:3651333 +100416551 Gm18157 MGI:MGI:5010342 +100416552 Gm18158 MGI:MGI:5010343 +100416555 Gm11862 MGI:MGI:3650456 +100416560 Gm18159 MGI:MGI:5010344 +100416577 Gm18160 MGI:MGI:5010345 +100416590 Gm18161 MGI:MGI:5010346 +100416593 Gm18162 MGI:MGI:5010347 +100416594 Gm18163 MGI:MGI:5010348 +100416601 Olfr1060-ps1 MGI:MGI:3030894 +100416615 Gm18164 MGI:MGI:5010349 +100416616 Gm18165 MGI:MGI:5010350 +100416617 Gm18166 MGI:MGI:5010351 +100416622 Gm13482 MGI:MGI:3651625 +100416624 LOC100416624 - +100416643 Gm11764 MGI:MGI:3651078 +100416644 Gm18167 MGI:MGI:5010352 +100416648 Gm18168 MGI:MGI:5010353 +100416650 Gm18169 MGI:MGI:5010354 +100416652 Gm18170 MGI:MGI:5010355 +100416653 Gm14576 MGI:MGI:3705593 +100416655 Gm14797 MGI:MGI:3705600 +100416656 Gm18171 MGI:MGI:5010356 +100416657 Gm18172 MGI:MGI:5010357 +100416658 Gm15000 MGI:MGI:3705392 +100416659 Gm18173 MGI:MGI:5010358 +100416660 Gm18174 MGI:MGI:5010359 +100416662 Gm18175 MGI:MGI:5010360 +100416663 Gm18176 MGI:MGI:5010361 +100416664 Gm17541 MGI:MGI:4937175 +100416666 Gm18177 MGI:MGI:5010362 +100416667 Gm18178 MGI:MGI:5010363 +100416668 Gm18179 MGI:MGI:5010364 +100416669 Gm18180 MGI:MGI:5010365 +100416670 Gm18181 MGI:MGI:5010366 +100416671 Gm18182 MGI:MGI:5010367 +100416672 Gm18183 MGI:MGI:5010368 +100416673 Gm18184 MGI:MGI:5010369 +100416674 Gm11609 MGI:MGI:3694969 +100416675 Gm18185 MGI:MGI:5010370 +100416676 Gm18186 MGI:MGI:5010371 +100416678 Gm18187 MGI:MGI:5010372 +100416679 Gm18188 MGI:MGI:5010373 +100416680 Gm18189 MGI:MGI:5010374 +100416683 Gm18190 MGI:MGI:5010375 +100416684 Gm18191 MGI:MGI:5010376 +100416685 Gm18192 MGI:MGI:5010377 +100416686 Gm18193 MGI:MGI:5010378 +100416687 Gm18194 MGI:MGI:5010379 +100416688 Gm18195 MGI:MGI:5010380 +100416689 Gm18196 MGI:MGI:5010381 +100416690 Gm18197 MGI:MGI:5010382 +100416691 Gm18198 MGI:MGI:5010383 +100416692 Gm18199 MGI:MGI:5010384 +100416693 Gm18200 MGI:MGI:5010385 +100416694 Gm18201 MGI:MGI:5010386 +100416697 Gm18204 MGI:MGI:5010389 +100416698 Gm18205 MGI:MGI:5010390 +100416699 Gm18206 MGI:MGI:5010391 +100416700 Gm18207 MGI:MGI:5010392 +100416701 Gm10988 MGI:MGI:3779203 +100416702 Gm12768 MGI:MGI:3649642 +100416703 Gm12773 MGI:MGI:3649904 +100416704 Gm18208 MGI:MGI:5010393 +100416706 Zfp729b MGI:MGI:2145180|Ensembl:ENSMUSG00000058093|Vega:OTTMUSG00000033503 +100416709 Gm18209 MGI:MGI:5010394 +100416710 Gm18210 MGI:MGI:5010395 +100416714 Gm18211 MGI:MGI:5010396 +100416715 Gm18212 MGI:MGI:5010397 +100416719 Gm18213 MGI:MGI:5010398 +100416721 Gm18214 MGI:MGI:5010399 +100416725 Gm18215 MGI:MGI:5010400 +100416726 Gm18216 MGI:MGI:5010401 +100416728 Gm18217 MGI:MGI:5010402 +100416729 Gm18218 MGI:MGI:5010403 +100416730 Gm15382 MGI:MGI:3705661 +100416733 Gm11510 MGI:MGI:3650711 +100416738 Gm18219 MGI:MGI:5010404 +100416739 Gm18220 MGI:MGI:5010405 +100416740 Gm12845 MGI:MGI:3651666 +100416742 Gm18221 MGI:MGI:5010406 +100416743 Gm18222 MGI:MGI:5010407 +100416744 Gm18223 MGI:MGI:5010408 +100416745 Gm18224 MGI:MGI:5010409 +100416747 Gm18225 MGI:MGI:5010410 +100416748 Gm18226 MGI:MGI:5010411 +100416749 Gm18227 MGI:MGI:5010412 +100416750 Gm18228 MGI:MGI:5010413 +100416751 Gm18229 MGI:MGI:5010414 +100416753 Gm18230 MGI:MGI:5010415 +100416754 Gm18231 MGI:MGI:5010416 +100416756 Gm18232 MGI:MGI:5010417 +100416757 Gm18233 MGI:MGI:5010418 +100416758 Gm14103 MGI:MGI:3650658 +100416759 Gm13366 MGI:MGI:3651974 +100416761 Gm15746 MGI:MGI:3783188 +100416762 Gm18234 MGI:MGI:5010419 +100416763 Gm18235 MGI:MGI:5010420 +100416764 Gm18236 MGI:MGI:5010421 +100416765 Gm18237 MGI:MGI:5010422 +100416766 Gm18238 MGI:MGI:5010423 +100416767 Gm18239 MGI:MGI:5010424 +100416769 Gm14665 MGI:MGI:3705438 +100416770 Gm14679 MGI:MGI:3705721 +100416771 Gm18240 MGI:MGI:5010425 +100416772 Gm18241 MGI:MGI:5010426 +100416773 Gm18242 MGI:MGI:5010427 +100416774 Gm18243 MGI:MGI:5010428 +100416777 Gm18244 MGI:MGI:5010429 +100416778 Gm18245 MGI:MGI:5010430 +100416779 Gm18246 MGI:MGI:5010431 +100416780 Gm17138 MGI:MGI:4937965 +100416781 Gm18247 MGI:MGI:5010432 +100416782 Gm18248 MGI:MGI:5010433 +100416783 Gm18249 MGI:MGI:5010434 +100416784 Gm15826 MGI:MGI:3801881 +100416786 Gm20585 MGI:MGI:5295691 +100416787 Gm18250 MGI:MGI:5010435 +100416788 Gm18251 MGI:MGI:5010436 +100416790 Gm18252 MGI:MGI:5010437 +100416791 Gm18253 MGI:MGI:5010438 +100416792 Gm18254 MGI:MGI:5010439 +100416793 Gm18255 MGI:MGI:5010440 +100416794 Gm18256 MGI:MGI:5010441 +100416795 Gm18257 MGI:MGI:5010442 +100416796 Gm18258 MGI:MGI:5010443 +100416797 Gm18259 MGI:MGI:5010444 +100416798 Gm11350 MGI:MGI:3652299 +100416799 Gm18260 MGI:MGI:5010445 +100416800 Gm18261 MGI:MGI:5010446 +100416801 Gm18262 MGI:MGI:5010447 +100416802 Gm18263 MGI:MGI:5010448 +100416804 Gm18265 MGI:MGI:5010450 +100416805 Gm18266 MGI:MGI:5010451 +100416806 Gm18267 MGI:MGI:5010452 +100416807 Gm9772 MGI:MGI:3641789 +100416808 Zfp422-ps MGI:MGI:3028594 +100416809 Gm18268 MGI:MGI:5010453 +100416810 Gm18269 MGI:MGI:5010454 +100416811 Gm18270 MGI:MGI:5010455 +100416812 Gm18271 MGI:MGI:5010456 +100416813 Gm18272 MGI:MGI:5010457 +100416814 Gm18273 MGI:MGI:5010458 +100416816 Gm18274 MGI:MGI:5010459 +100416817 Gm18275 MGI:MGI:5010460 +100416818 Gm18276 MGI:MGI:5010461 +100416819 Gm18277 MGI:MGI:5010462 +100416820 Gm18278 MGI:MGI:5010463 +100416821 Gm18279 MGI:MGI:5010464 +100416822 Gm18280 MGI:MGI:5010465 +100416823 Gm18281 MGI:MGI:5010466 +100416824 Gm6172 MGI:MGI:3779563 +100416825 Gm18282 MGI:MGI:5010467 +100416826 Gm18283 MGI:MGI:5010468 +100416827 Gm18284 MGI:MGI:5010469 +100416828 Gm16030 MGI:MGI:3801713 +100416829 Gm18285 MGI:MGI:5010470 +100416830 Zfp572 MGI:MGI:1922170|Ensembl:ENSMUSG00000098528 +100416831 Gm12179 MGI:MGI:3651494 +100416834 Gm18286 MGI:MGI:5010471 +100416835 Gm18287 MGI:MGI:5010472 +100416838 Gm12327 MGI:MGI:3651321 +100416839 Gm11797 MGI:MGI:3651074 +100416840 Gm11853 MGI:MGI:3649490 +100416841 Gm18288 MGI:MGI:5010473 +100416842 Gm18289 MGI:MGI:5010474 +100416843 Gm18290 MGI:MGI:5010475 +100416845 Gm15780 MGI:MGI:3783222 +100416846 Gm18291 MGI:MGI:5010476 +100416847 Gm18292 MGI:MGI:5010477 +100416852 Gm18293 MGI:MGI:5010478 +100416861 Gm18294 MGI:MGI:5010479 +100416866 Gm18295 MGI:MGI:5010480 +100416867 Gm18296 MGI:MGI:5010481 +100416868 Pgk1-ps3 MGI:MGI:97558 +100416869 Gm13379 MGI:MGI:3649905 +100416870 Gm13521 MGI:MGI:3650804 +100416871 Gm29693 MGI:MGI:5588852 +100416872 Gm16011 MGI:MGI:3801796 +100416873 Gm14840 MGI:MGI:3801922 +100416874 Gm14537 MGI:MGI:3648060 +100416875 Gm14627 MGI:MGI:3646602 +100416876 Gm18297 MGI:MGI:5010482 +100416877 Gm14833 MGI:MGI:3802101 +100416878 Gm18298 MGI:MGI:5010483 +100416879 Gm9356 MGI:MGI:3648509 +100416880 Gm20947 MGI:MGI:5434302 +100416881 Gm18299 MGI:MGI:5010484 +100416882 Gm18300 MGI:MGI:5010485 +100416883 Gm18301 MGI:MGI:5010486 +100416884 Gm18302 MGI:MGI:5010487 +100416885 Gm18303 MGI:MGI:5010488 +100416887 Gm18304 MGI:MGI:5010489 +100416888 Gm7496 MGI:MGI:3643469 +100416889 Gm18305 MGI:MGI:5010490 +100416896 Gm18306 MGI:MGI:5010491 +100416897 Gm18307 MGI:MGI:5010492 +100416898 Gm18308 MGI:MGI:5010493 +100416899 Gm18309 MGI:MGI:5010494 +100416900 Gm18310 MGI:MGI:5010495 +100416908 Gm18311 MGI:MGI:5010496 +100416909 Gm18312 MGI:MGI:5010497 +100416910 Gm18313 MGI:MGI:5010498 +100416911 Gm18314 MGI:MGI:5010499 +100416912 Gm18315 MGI:MGI:5010500 +100416913 Gm18316 MGI:MGI:5010501 +100416914 Gm18317 MGI:MGI:5010502 +100416915 Gm18318 MGI:MGI:5010503 +100416916 Gm18319 MGI:MGI:5010504 +100416917 Gm18320 MGI:MGI:5010505 +100416918 Gm7371 MGI:MGI:3643484 +100416919 Gm18321 MGI:MGI:5010506 +100416920 Gm18322 MGI:MGI:5010507 +100416921 Gm18323 MGI:MGI:5010508 +100416922 Gm11790 MGI:MGI:3649211 +100416923 Gm18324 MGI:MGI:5010509 +100416924 Gm11885 MGI:MGI:3649645 +100416925 Gm12413 MGI:MGI:3650373 +100416930 Gm18325 MGI:MGI:5010510 +100416931 Gm18326 MGI:MGI:5010511 +100416932 Gm18327 MGI:MGI:5010512 +100416933 Gm13724 MGI:MGI:3651278 +100416934 Gm3729 MGI:MGI:3781904 +100416942 Gm15576 MGI:MGI:3783024 +100416943 Gm18328 MGI:MGI:5010513 +100416944 Gm15586 MGI:MGI:3783034 +100416945 Gm18329 MGI:MGI:5010514 +100416946 Gm15968 MGI:MGI:3801809 +100416947 Gm18330 MGI:MGI:5010515 +100416948 Gm18331 MGI:MGI:5010516 +100416949 Gm14208 MGI:MGI:3649780 +100416950 Gm18332 MGI:MGI:5010517 +100416951 Gm18333 MGI:MGI:5010518 +100416952 Hmgb1-ps6 MGI:MGI:3776507 +100416953 Gm18334 MGI:MGI:5010519 +100416954 Gm18335 MGI:MGI:5010520 +100416955 Gm14887 MGI:MGI:3801913 +100416956 Gm18336 MGI:MGI:5010521 +100416958 Gm15186 MGI:MGI:3705337 +100416959 Gm18337 MGI:MGI:5010522 +100416960 Gm18338 MGI:MGI:5010523 +100416961 Gm18339 MGI:MGI:5010524 +100416965 Gm18340 MGI:MGI:5010525 +100416968 Gm18341 MGI:MGI:5010526 +100416971 Gm18342 MGI:MGI:5010527 +100416974 Gm18343 MGI:MGI:5010528 +100416975 Gm18344 MGI:MGI:5010529 +100416976 Gm18345 MGI:MGI:5010530 +100416977 Gm7171 MGI:MGI:3649028 +100416979 Gm18346 MGI:MGI:5010531 +100416984 Gm18347 MGI:MGI:5010532 +100416987 Gm18348 MGI:MGI:5010533 +100416988 Gm18349 MGI:MGI:5010534 +100416990 Gm18350 MGI:MGI:5010535 +100416993 Gm18351 MGI:MGI:5010536 +100416994 Gm18352 MGI:MGI:5010537 +100416995 Gm18353 MGI:MGI:5010538 +100416998 Gm18354 MGI:MGI:5010539 +100417000 Obox3-ps7 MGI:MGI:5010540 +100417005 Gm18356 MGI:MGI:5010541 +100417006 Gm18357 MGI:MGI:5010542 +100417008 Gm18358 MGI:MGI:5010543 +100417009 Gm18359 MGI:MGI:5010544 +100417010 Gm18360 MGI:MGI:5010545 +100417013 Gm18361 MGI:MGI:5010546 +100417014 Gm18362 MGI:MGI:5010547 +100417015 Gm18363 MGI:MGI:5010548 +100417016 Gm16318 MGI:MGI:3826563 +100417018 Gm18364 MGI:MGI:5010549 +100417019 Gm20948 MGI:MGI:5434303 +100417020 Gm18365 MGI:MGI:5010550 +100417021 Gm18366 MGI:MGI:5010551 +100417023 Gm18367 MGI:MGI:5010552 +100417024 Hmgb3-ps MGI:MGI:4414963 +100417025 Gm18368 MGI:MGI:5010553 +100417026 Gm18369 MGI:MGI:5010554 +100417027 Gm18370 MGI:MGI:5010555 +100417028 Gm18371 MGI:MGI:5010556 +100417029 Gm18372 MGI:MGI:5010557 +100417031 Gm18373 MGI:MGI:5010558 +100417033 Gm18374 MGI:MGI:5010559 +100417034 LOC100417034 - +100417035 Gm18375 MGI:MGI:5010560 +100417037 Gm18377 MGI:MGI:5010562 +100417038 Gm18378 MGI:MGI:5010563 +100417040 Gm18379 MGI:MGI:5010564 +100417041 Gm18380 MGI:MGI:5010565 +100417043 Gm18381 MGI:MGI:5010566 +100417044 Gm18382 MGI:MGI:5010567 +100417046 Gm18384 MGI:MGI:5010569 +100417047 Gm13323 MGI:MGI:3650423 +100417048 Gm14213 MGI:MGI:3650245 +100417049 Gm18385 MGI:MGI:5010570 +100417050 Gm7645 MGI:MGI:3646877 +100417052 Gm18386 MGI:MGI:5010571 +100417053 Gm14804 MGI:MGI:3705571 +100417054 Gm18387 MGI:MGI:5010572 +100417055 Gm18388 MGI:MGI:5010573 +100417058 Gm18389 MGI:MGI:5010574 +100417059 Gm18390 MGI:MGI:5010575 +100417060 Gm18391 MGI:MGI:5010576 +100417062 Gm18392 MGI:MGI:5010577 +100417089 Gm18393 MGI:MGI:5010578 +100417090 Gm18394 MGI:MGI:5010579 +100417091 Gm18395 MGI:MGI:5010580 +100417097 Gm18396 MGI:MGI:5010581 +100417098 Gm18397 MGI:MGI:5010582 +100417103 Gm18398 MGI:MGI:5010583 +100417104 Gm18399 MGI:MGI:5010584 +100417106 Gm12004 MGI:MGI:3651315 +100417107 Gm15741 MGI:MGI:3783183 +100417108 Gm18400 MGI:MGI:5010585 +100417109 Gm18401 MGI:MGI:5010586 +100417110 Gm18402 MGI:MGI:5010587 +100417112 Gm18403 MGI:MGI:5010588 +100417113 Gm13440 MGI:MGI:3650985 +100417114 Gm18404 MGI:MGI:5010589 +100417115 Gm13930 MGI:MGI:3649395 +100417116 Gm14943 MGI:MGI:3705626 +100417117 Gm15011 MGI:MGI:3705394 +100417118 Gm15160 MGI:MGI:3705557 +100417119 Gm18405 MGI:MGI:5010590 +100417120 Gm18406 MGI:MGI:5010591 +100417121 Gm15618 MGI:MGI:3783063 +100417122 Gm18407 MGI:MGI:5010592 +100417123 Gm18408 MGI:MGI:5010593 +100417125 Gm18409 MGI:MGI:5010594|Ensembl:ENSMUSG00000112503 +100417127 Gm18410 MGI:MGI:5010595 +100417128 Gm18411 MGI:MGI:5010596 +100417129 Gm18412 MGI:MGI:5010597 +100417130 Gm18413 MGI:MGI:5010598 +100417132 Gm18414 MGI:MGI:5010599 +100417133 Gm18415 MGI:MGI:5010600 +100417134 Gm18416 MGI:MGI:5010601 +100417135 Gm18417 MGI:MGI:5010602 +100417136 Gm17228 MGI:MGI:4938055 +100417137 Gm18418 MGI:MGI:5010603 +100417138 Gm18419 MGI:MGI:5010604 +100417141 Gm18420 MGI:MGI:5010605 +100417142 Gm12047 MGI:MGI:3652082 +100417144 Gm11708 MGI:MGI:3649475 +100417145 Gm6608 MGI:MGI:3779615 +100417146 Gm18421 MGI:MGI:5010606 +100417147 Gm18422 MGI:MGI:5010607 +100417148 Gm18423 MGI:MGI:5010608 +100417152 Gm18425 MGI:MGI:5010610 +100417153 Gm18426 MGI:MGI:5010611 +100417154 Gm18427 MGI:MGI:5010612 +100417155 Gm18428 MGI:MGI:5010613 +100417157 Gm18429 MGI:MGI:5010614 +100417158 Gm18430 MGI:MGI:5010615 +100417159 Gm18431 MGI:MGI:5010616 +100417160 Gm18432 MGI:MGI:5010617 +100417161 Gm18433 MGI:MGI:5010618 +100417166 Gm14097 MGI:MGI:3651729 +100417167 Gm18434 MGI:MGI:5010619 +100417168 Gm13452 MGI:MGI:3651621 +100417169 Gm13566 MGI:MGI:3649655 +100417170 Gm18435 MGI:MGI:5010620 +100417171 Gm18436 MGI:MGI:5010621 +100417172 Gm18437 MGI:MGI:5010622 +100417173 Gm14609 MGI:MGI:3641630 +100417174 Gm14704 MGI:MGI:3705531 +100417175 Gm14722 MGI:MGI:3705731 +100417178 Gm18438 MGI:MGI:5010623 +100417179 Gm18439 MGI:MGI:5010624 +100417181 Gm14824 MGI:MGI:3802065 +100417183 Gm14976 MGI:MGI:3705719 +100417184 Gm14977 MGI:MGI:3705506 +100417185 Gm14981 MGI:MGI:3712457 +100417186 Gm15073 MGI:MGI:3705417 +100417187 Gm14655 MGI:MGI:3705748 +100417188 Gm14656 MGI:MGI:3705637 +100417189 Gm18440 MGI:MGI:5010625 +100417190 Gm14729 MGI:MGI:3705648 +100417191 Gm14726 MGI:MGI:3705741 +100417192 Gm14971 MGI:MGI:3705577 +100417193 Gm15022 MGI:MGI:3782930 +100417194 Gm15158 MGI:MGI:3705763 +100417195 Gm18441 MGI:MGI:5010626 +100417196 Gm18442 MGI:MGI:5010627 +100417198 Gm18443 MGI:MGI:5010628 +100417199 Gm18444 MGI:MGI:5010629 +100417200 Gm16332 MGI:MGI:3840155 +100417201 Gm18445 MGI:MGI:5010630 +100417202 Gm18446 MGI:MGI:5010631 +100417203 Gm18447 MGI:MGI:5010632 +100417204 Gm18448 MGI:MGI:5010633 +100417205 Gm18449 MGI:MGI:5010634 +100417206 Gm18450 MGI:MGI:5010635 +100417207 Gm18451 MGI:MGI:5010636 +100417208 Gm18452 MGI:MGI:5010637 +100417211 Gm18453 MGI:MGI:5010638 +100417212 Gm18454 MGI:MGI:5010639 +100417214 Gm15116 MGI:MGI:3705687 +100417215 Gm38420 MGI:MGI:5621305 +100417216 Gm18455 MGI:MGI:5010640 +100417217 Gm18456 MGI:MGI:5010641 +100417219 Gm18458 MGI:MGI:5010643 +100417220 Gm18459 MGI:MGI:5010644 +100417221 Gm18460 MGI:MGI:5010645 +100417222 Gm18461 MGI:MGI:5010646 +100417223 Gm18462 MGI:MGI:5010647 +100417224 Gm18463 MGI:MGI:5010648 +100417225 Gm18464 MGI:MGI:5010649 +100417226 Gm18465 MGI:MGI:5010650 +100417227 Gm18466 MGI:MGI:5010651 +100417228 Gm18467 MGI:MGI:5010652 +100417229 Gm18468 MGI:MGI:5010653 +100417230 Gm18469 MGI:MGI:5010654 +100417231 Gm18470 MGI:MGI:5010655 +100417232 Gm18471 MGI:MGI:5010656 +100417233 Gm18472 MGI:MGI:5010657 +100417234 Gm18473 MGI:MGI:5010658 +100417236 Gm18474 MGI:MGI:5010659 +100417237 Gm18475 MGI:MGI:5010660 +100417239 Gm18476 MGI:MGI:5010661 +100417241 Gm18477 MGI:MGI:5010662 +100417242 Gm18478 MGI:MGI:5010663 +100417243 Gm12041 MGI:MGI:3651844 +100417244 Gm18479 MGI:MGI:5010664 +100417245 Gm12805 MGI:MGI:3650124 +100417246 Gm12948 MGI:MGI:3649530 +100417247 Gm12635 MGI:MGI:3650766 +100417248 Gm18480 MGI:MGI:5010665 +100417249 Gm18481 MGI:MGI:5010666 +100417251 Gm13898 MGI:MGI:3652332 +100417252 Gm18482 MGI:MGI:5010667 +100417253 Gm18483 MGI:MGI:5010668 +100417254 Gm18484 MGI:MGI:5010669 +100417257 Gm18485 MGI:MGI:5010670 +100417258 Gm18486 MGI:MGI:5010671 +100417260 Gm18487 MGI:MGI:5010672 +100417262 Gm18488 MGI:MGI:5010673 +100417263 Gm18489 MGI:MGI:5010674 +100417264 Gm18490 MGI:MGI:5010675 +100417265 Gm18491 MGI:MGI:5010676 +100417266 LOC100417266 - +100417267 Gm18492 MGI:MGI:5010677 +100417268 Gm18493 MGI:MGI:5010678 +100417269 Gm18494 MGI:MGI:5010679 +100417270 Gm14020 MGI:MGI:3651446 +100417271 Gm18495 MGI:MGI:5010680 +100417272 Gm18496 MGI:MGI:5010681 +100417273 Gm18497 MGI:MGI:5010682 +100417274 Gm15013 MGI:MGI:3644991 +100417275 Gm15105 MGI:MGI:3705328 +100417276 Gm14514 MGI:MGI:3705639 +100417277 Gm14979 MGI:MGI:3705699 +100417278 Gm15071 MGI:MGI:3705503 +100417279 Gm18498 MGI:MGI:5010683 +100417280 Gm15238 MGI:MGI:3641766 +100417281 Gm18499 MGI:MGI:5010684 +100417282 Gm18500 MGI:MGI:5010685 +100417283 Gm18501 MGI:MGI:5010686 +100417284 Gm18502 MGI:MGI:5010687 +100417285 Gm18503 MGI:MGI:5010688 +100417286 Gm18504 MGI:MGI:5010689 +100417287 Gm18505 MGI:MGI:5010690 +100417288 Gm18506 MGI:MGI:5010691 +100417290 Gm18507 MGI:MGI:5010692 +100417291 Gm18508 MGI:MGI:5010693 +100417292 Gm18509 MGI:MGI:5010694 +100417293 Gm18510 MGI:MGI:5010695 +100417294 Gm17230 MGI:MGI:4938057 +100417295 Gm18511 MGI:MGI:5010696 +100417296 Gm18512 MGI:MGI:5010697 +100417297 Gm18513 MGI:MGI:5010698 +100417298 Gm18514 MGI:MGI:5010699 +100417299 Gm18515 MGI:MGI:5010700 +100417301 Gm18516 MGI:MGI:5010701 +100417303 Gm18517 MGI:MGI:5010702 +100417305 Gm18518 MGI:MGI:5010703 +100417306 Gm18519 MGI:MGI:5010704 +100417307 Gm18520 MGI:MGI:5010705 +100417309 Gm18521 MGI:MGI:5010706 +100417310 Gm18522 MGI:MGI:5010707 +100417311 Gm17070 MGI:MGI:4937897 +100417312 Gm18523 MGI:MGI:5010708 +100417313 Gm18524 MGI:MGI:5010709 +100417314 Gm18525 MGI:MGI:5010710 +100417315 Gm18526 MGI:MGI:5010711 +100417316 Gm18527 MGI:MGI:5010712 +100417317 Gm18528 MGI:MGI:5010713 +100417318 Gm18529 MGI:MGI:5010714 +100417319 Gm18530 MGI:MGI:5010715 +100417320 Gm18531 MGI:MGI:5010716 +100417321 Gm21997 MGI:MGI:5440226 +100417322 Gm18532 MGI:MGI:5010717 +100417323 Gm18533 MGI:MGI:5010718 +100417326 Gm11498 MGI:MGI:3650889 +100417327 Gm11661 MGI:MGI:3651387 +100417328 Gm18534 MGI:MGI:5010719 +100417329 Gm12852 MGI:MGI:3651942 +100417330 Gm18535 MGI:MGI:5010720 +100417331 Mup-ps1 MGI:MGI:3651069 +100417333 Gm13153 MGI:MGI:3651987 +100417334 Gm18537 MGI:MGI:5010722 +100417335 Gm18538 MGI:MGI:5010723 +100417336 Gm18539 MGI:MGI:5010724 +100417337 Gm18540 MGI:MGI:5010725 +100417338 Gm18541 MGI:MGI:5010726 +100417339 Gm18542 MGI:MGI:5010727 +100417340 Gm18543 MGI:MGI:5010728 +100417341 Gm18544 MGI:MGI:5010729 +100417342 Gm18545 MGI:MGI:5010730 +100417343 Gm18546 MGI:MGI:5010731 +100417344 Gm18547 MGI:MGI:5010732 +100417345 Gm18548 MGI:MGI:5010733 +100417346 Gm13608 MGI:MGI:3651499 +100417347 Gm18549 MGI:MGI:5010734 +100417348 Gm18550 MGI:MGI:5010735 +100417349 Gm14869 MGI:MGI:3705472 +100417350 Gm18551 MGI:MGI:5010736 +100417351 Gm18552 MGI:MGI:5010737 +100417352 Gm18553 MGI:MGI:5010738 +100417355 Gm18555 MGI:MGI:5010740 +100417356 Gm18556 MGI:MGI:5010741 +100417357 Gm18557 MGI:MGI:5010742 +100417358 Gm18558 MGI:MGI:5010743 +100417360 Gm18559 MGI:MGI:5010744 +100417361 Gm18560 MGI:MGI:5010745 +100417362 Gm18561 MGI:MGI:5010746 +100417363 Gm18562 MGI:MGI:5010747 +100417364 Gm18563 MGI:MGI:5010748 +100417365 Gm18564 MGI:MGI:5010749 +100417366 Gm18565 MGI:MGI:5010750 +100417368 Gm18567 MGI:MGI:5010752 +100417369 Gm18568 MGI:MGI:5010753 +100417370 Gm18569 MGI:MGI:5010754 +100417372 Gm18571 MGI:MGI:5010756 +100417373 Gm18572 MGI:MGI:5010757 +100417374 Gm18573 MGI:MGI:5010758 +100417375 Gm18574 MGI:MGI:5010759 +100417376 Gm18575 MGI:MGI:5010760 +100417377 Gm18576 MGI:MGI:5010761 +100417378 Gm18577 MGI:MGI:5010762 +100417379 Gm18578 MGI:MGI:5010763 +100417380 Gm18579 MGI:MGI:5010764 +100417381 Gm18580 MGI:MGI:5010765 +100417382 Gm18581 MGI:MGI:5010766 +100417383 Gm18582 MGI:MGI:5010767 +100417384 Gm15381 MGI:MGI:3707455 +100417385 Gm18583 MGI:MGI:5010768 +100417387 Gm12636 MGI:MGI:3650767 +100417388 Gm12899 MGI:MGI:3650162 +100417389 Gm18584 MGI:MGI:5010769 +100417390 Gm18585 MGI:MGI:5010770 +100417391 Gm18586 MGI:MGI:5010771 +100417392 Gm15625 MGI:MGI:3783069 +100417393 Gm18587 MGI:MGI:5010772 +100417394 Gm18588 MGI:MGI:5010773 +100417395 Gm13865 MGI:MGI:3651348 +100417396 Gm18589 MGI:MGI:5010774 +100417397 Gm14099 MGI:MGI:3651731 +100417398 Gm13633 MGI:MGI:3651356 +100417399 Pex13-ps MGI:MGI:3652047 +100417400 Gm18590 MGI:MGI:5010775 +100417402 Gm14695 MGI:MGI:3705851 +100417403 Gm18591 MGI:MGI:5010776 +100417405 Gm18592 MGI:MGI:5010777 +100417406 Gm18593 MGI:MGI:5010778 +100417407 Gm18594 MGI:MGI:5010779 +100417408 Gm18595 MGI:MGI:5010780 +100417409 Gm18596 MGI:MGI:5010781 +100417411 Gm18597 MGI:MGI:5010782 +100417412 Gm18598 MGI:MGI:5010783 +100417414 Gm8523 MGI:MGI:3779801 +100417415 Gm18599 MGI:MGI:5010784 +100417417 Gm18600 MGI:MGI:5010785 +100417419 Gm18601 MGI:MGI:5010786 +100417420 Gm18602 MGI:MGI:5010787 +100417421 Gm18603 MGI:MGI:5010788 +100417422 Gm16574 MGI:MGI:4414994 +100417423 Gm18604 MGI:MGI:5010789 +100417424 Gm18605 MGI:MGI:5010790 +100417425 Gm18606 MGI:MGI:5010791 +100417426 Gm12345 MGI:MGI:3649862 +100417427 Gm18607 MGI:MGI:5010792 +100417429 Gm12998 MGI:MGI:3651168 +100417430 Gm18608 MGI:MGI:5010793 +100417431 Gm18609 MGI:MGI:5010794 +100417434 AA543401 MGI:MGI:2155152|Ensembl:ENSMUSG00000092125 +100417435 Gm18610 MGI:MGI:5010795 +100417436 Gm18611 MGI:MGI:5010796 +100417437 Gm2988 MGI:MGI:3781166 +100417439 Gm13535 MGI:MGI:3651247 +100417440 Gm14278 MGI:MGI:3650108 +100417441 Gm18612 MGI:MGI:5010797 +100417443 Gm18613 MGI:MGI:5010798 +100417445 Gm14786 MGI:MGI:3705742 +100417446 Gm15172 MGI:MGI:3705733 +100417448 Gm14935 MGI:MGI:3802130 +100417449 Gm14907 MGI:MGI:3705397 +100417450 Gm18614 MGI:MGI:5010799 +100417451 Gm15132 MGI:MGI:3705367 +100417452 Gm18615 MGI:MGI:5010800 +100417453 Gm18616 MGI:MGI:5010801 +100417454 LOC100417454 - +100417455 Gm18617 MGI:MGI:5010802 +100417456 Gm18618 MGI:MGI:5010803 +100417457 Gm18619 MGI:MGI:5010804 +100417458 Gm18620 MGI:MGI:5010805 +100417459 Gm18621 MGI:MGI:5010806 +100417460 Gm18622 MGI:MGI:5010807 +100417461 Gm18623 MGI:MGI:5010808 +100417462 Gm18624 MGI:MGI:5010809 +100417463 Gm18625 MGI:MGI:5010810 +100417464 Gm18626 MGI:MGI:5010811 +100417465 Gm18627 MGI:MGI:5010812 +100417466 Gm18628 MGI:MGI:5010813 +100417467 Gm18629 MGI:MGI:5010814 +100417468 Gm18630 MGI:MGI:5010815 +100417469 Gm18631 MGI:MGI:5010816 +100417470 Gm18632 MGI:MGI:5010817 +100417473 Gm17101 MGI:MGI:4937928 +100417474 Gm16102 MGI:MGI:3802041 +100417475 Gm18633 MGI:MGI:5010818 +100417476 Gm15789 MGI:MGI:3783231 +100417477 Gm18634 MGI:MGI:5010819 +100417478 Gm18635 MGI:MGI:5010820 +100417479 Gm18636 MGI:MGI:5010821 +100417480 Gm18637 MGI:MGI:5010822 +100417481 Gm18638 MGI:MGI:5010823 +100417482 Gm18639 MGI:MGI:5010824 +100417483 Gm18640 MGI:MGI:5010825 +100417484 Gm18641 MGI:MGI:5010826 +100417488 Gm18642 MGI:MGI:5010827 +100417489 Gm17137 MGI:MGI:4937964 +100417490 Gm16044 MGI:MGI:3801992 +100417491 Gm18643 MGI:MGI:5010828 +100417492 Gm18644 MGI:MGI:5010829 +100417493 Gm20586 MGI:MGI:5295692 +100417494 Gm18645 MGI:MGI:5010830 +100417495 Gm18646 MGI:MGI:5010831 +100417496 Gm17072 MGI:MGI:4937899 +100417498 Gm18648 MGI:MGI:5010833 +100417499 Gm18649 MGI:MGI:5010834 +100417500 Gm18650 MGI:MGI:5010835 +100417501 Gm18651 MGI:MGI:5010836 +100417502 Gm18652 MGI:MGI:5010837 +100417503 Gm18653 MGI:MGI:5010838 +100417504 Gm18654 MGI:MGI:5010839 +100417505 Gm12667 MGI:MGI:3651935 +100417506 Gm16123 MGI:MGI:3801766 +100417507 Gm18655 MGI:MGI:5010840 +100417508 Gm18656 MGI:MGI:5010841 +100417509 Gm18657 MGI:MGI:5010842 +100417510 Gm18658 MGI:MGI:5010843 +100417511 Gm18659 MGI:MGI:5010844 +100417512 Gm18660 MGI:MGI:5010845 +100417513 Gm18661 MGI:MGI:5010846 +100417514 Adh6b MGI:MGI:2446626|Ensembl:ENSMUSG00000074206|Vega:OTTMUSG00000052832 +100417515 Gm13396 MGI:MGI:3651850 +100417516 Gm18662 MGI:MGI:5010847 +100417517 Gm15970 MGI:MGI:3801995 +100417518 Gm18663 MGI:MGI:5010848 +100417519 Gm14667 MGI:MGI:3705673 +100417520 Gm18664 MGI:MGI:5010849 +100417521 Gm15065 MGI:MGI:3705525 +100417523 Gm14854 MGI:MGI:3705597 +100417524 Gm14894 MGI:MGI:3705757 +100417526 Gm18665 MGI:MGI:5010850 +100417527 Gm18666 MGI:MGI:5010851 +100417528 Gm18667 MGI:MGI:5010852 +100417529 Gm18668 MGI:MGI:5010853 +100417530 Gm15975 MGI:MGI:3801944 +100417531 Gm18669 MGI:MGI:5010854 +100417532 Gm18670 MGI:MGI:5010855 +100417533 Gm15136 MGI:MGI:3705838 +100417534 Gm18671 MGI:MGI:5010856 +100417535 Gm18672 MGI:MGI:5010857 +100417538 Gm18673 MGI:MGI:5010858 +100417539 Gm18674 MGI:MGI:5010859 +100417540 Gm17219 MGI:MGI:4938046 +100417541 Gm18675 MGI:MGI:5010860 +100417542 Gm18676 MGI:MGI:5010861 +100417543 Gm18677 MGI:MGI:5010862 +100417544 Gm18678 MGI:MGI:5010863 +100417545 Gm18679 MGI:MGI:5010864 +100417546 Rab5a-ps MGI:MGI:5010865 +100417548 Gm18681 MGI:MGI:5010866 +100417549 Gm18682 MGI:MGI:5010867 +100417550 Gm18683 MGI:MGI:5010868 +100417552 Gm18684 MGI:MGI:5010869 +100417553 Gm18685 MGI:MGI:5010870 +100417554 Gm18686 MGI:MGI:5010871 +100417555 Gm12045 MGI:MGI:3651842 +100417556 Gm12577 MGI:MGI:3651713 +100417557 Gm18687 MGI:MGI:5010872 +100417558 Gm12388 MGI:MGI:3651412 +100417559 Gm12647 MGI:MGI:3649949 +100417560 Gm18688 MGI:MGI:5010873 +100417561 Gm18689 MGI:MGI:5010874 +100417562 Gm18690 MGI:MGI:5010875 +100417563 Gm18691 MGI:MGI:5010876 +100417564 Gm15595 MGI:MGI:3783042 +100417569 Gm18692 MGI:MGI:5010877 +100417571 Gm13217 MGI:MGI:3649713 +100417572 Gm18693 MGI:MGI:5010878 +100417573 Gm14065 MGI:MGI:3649739 +100417574 Gm14125 MGI:MGI:3650328 +100417576 Gm18694 MGI:MGI:5010879 +100417577 Gm18695 MGI:MGI:5010880 +100417578 Gm15001 MGI:MGI:3705407 +100417579 LOC100417579 - +100417580 Gm15040 MGI:MGI:3705331 +100417581 3110067C02Rik MGI:MGI:1920452 +100417582 Gm18696 MGI:MGI:5010881 +100417583 Gm18697 MGI:MGI:5010882 +100417584 Gm18698 MGI:MGI:5010883 +100417585 Gm16581 MGI:MGI:4415001 +100417586 Gm18699 MGI:MGI:5010884 +100417587 Gm18700 MGI:MGI:5010885 +100417588 Gm18701 MGI:MGI:5010886 +100417590 Gm18702 MGI:MGI:5010887 +100417591 Gm18703 MGI:MGI:5010888 +100417592 Gm18704 MGI:MGI:5010889 +100417593 Gm18705 MGI:MGI:5010890 +100417594 Gm15900 MGI:MGI:3801848 +100417596 Gm20949 MGI:MGI:5434304 +100417597 Gm18706 MGI:MGI:5010891 +100417598 Gm15773 MGI:MGI:3783214 +100417600 Gm18707 MGI:MGI:5010892 +100417602 Gm18708 MGI:MGI:5010893 +100417603 Gm11357 MGI:MGI:3713473 +100417604 Gm18709 MGI:MGI:5010894 +100417605 Gm18710 MGI:MGI:5010895 +100417606 Gm18711 MGI:MGI:5010896 +100417607 Gm18712 MGI:MGI:5010897 +100417608 Gm18713 MGI:MGI:5010898 +100417609 Gm16072 MGI:MGI:3801776 +100417610 Gm18714 MGI:MGI:5010899 +100417611 Gm18715 MGI:MGI:5010900 +100417613 Gm7543 MGI:MGI:3645066 +100417614 Gm13240 MGI:MGI:3650771 +100417615 Gm13243 MGI:MGI:3649654 +100417616 Gm18716 MGI:MGI:5010901 +100417618 Gm18717 MGI:MGI:5010902 +100417620 Gm18719 MGI:MGI:5010904 +100417621 Gm13451 MGI:MGI:3651620 +100417622 Gm18720 MGI:MGI:5010905 +100417623 Gm18721 MGI:MGI:5010906 +100417624 Gm18722 MGI:MGI:5010907 +100417625 Gm18723 MGI:MGI:5010908 +100417626 Gm18724 MGI:MGI:5010909 +100417627 LOC100417627 MGI:MGI:5010910 +100417628 Gm14739 MGI:MGI:3705446 +100417629 Gm14997 MGI:MGI:3705390 +100417630 Gm14994 MGI:MGI:3705326 +100417631 Gm14999 MGI:MGI:3705436 +100417632 Gm15004 MGI:MGI:3705666 +100417633 Gm14900 MGI:MGI:3705380 +100417634 Gm15006 MGI:MGI:3705347 +100417636 Gm18726 MGI:MGI:5010911 +100417637 Gm18727 MGI:MGI:5010912 +100417638 Gm18728 MGI:MGI:5010913 +100417639 Gm18729 MGI:MGI:5010914 +100417640 Gm18730 MGI:MGI:5010915 +100417641 Zbed4-ps3 MGI:MGI:5010916 +100417642 Zbed4-ps2 MGI:MGI:5010917 +100417643 Gm5605 MGI:MGI:3647902 +100417644 Gm18733 MGI:MGI:5010918 +100417645 Gm18734 MGI:MGI:5010919 +100417646 Gm18735 MGI:MGI:5010920 +100417647 Gm18736 MGI:MGI:5010921 +100417648 Gm18737 MGI:MGI:5010922 +100417649 Gm18738 MGI:MGI:5010923 +100417650 Gm18739 MGI:MGI:5010924 +100417651 Gm18740 MGI:MGI:5010925 +100417652 Gm18741 MGI:MGI:5010926 +100417653 Gm18742 MGI:MGI:5010927 +100417654 Gm12024 MGI:MGI:3650980 +100417655 Gm18743 MGI:MGI:5010928 +100417656 Gm18744 MGI:MGI:5010929 +100417659 Gm12804 MGI:MGI:3651639 +100417660 Gm18745 MGI:MGI:5010930 +100417662 Zcchc9-ps MGI:MGI:3651106 +100417663 Gm18747 MGI:MGI:5010932 +100417664 Gm18748 MGI:MGI:5010933 +100417665 LOC100417665 - +100417666 Gm14785 MGI:MGI:3705759 +100417668 Gm18749 MGI:MGI:5010934 +100417669 Gm18750 MGI:MGI:5010935 +100417670 Gm18751 MGI:MGI:5010936 +100417671 Gm18752 MGI:MGI:5010937 +100417672 Gm18753 MGI:MGI:5010938 +100417673 Gm18754 MGI:MGI:5010939 +100417674 Gm18755 MGI:MGI:5010940 +100417675 Nlrp5-ps MGI:MGI:5010941|Ensembl:ENSMUSG00000041596 +100417676 Gm18757 MGI:MGI:5010942 +100417677 Gm18758 MGI:MGI:5010943 +100417678 Gm18759 MGI:MGI:5010944 +100417679 Gm17709 MGI:MGI:4937343 +100417680 Gm18760 MGI:MGI:5010945 +100417681 Gm18761 MGI:MGI:5010946 +100417682 Gm18762 MGI:MGI:5010947 +100417683 Gm18763 MGI:MGI:5010948 +100417684 Gm18764 MGI:MGI:5010949 +100417685 Gm12093 MGI:MGI:3650093 +100417687 Gm12846 MGI:MGI:3651461 +100417688 Gm18765 MGI:MGI:5010950 +100417695 Gm18766 MGI:MGI:5010951 +100417697 Gm18767 MGI:MGI:5010952 +100417698 Gm18768 MGI:MGI:5010953 +100417699 Gm18769 MGI:MGI:5010954 +100417700 Gm15530 MGI:MGI:3782978 +100417701 Gm18770 MGI:MGI:5010955 +100417702 Gm18771 MGI:MGI:5010956 +100417703 Gm18772 MGI:MGI:5010957 +100417704 Gm18773 MGI:MGI:5010958 +100417705 Gm14829 MGI:MGI:3708092 +100417706 Gm14841 MGI:MGI:3802164 +100417707 9530050K03Rik MGI:MGI:1925871 +100417709 Gm18774 MGI:MGI:5010959 +100417711 Gm18775 MGI:MGI:5010960 +100417712 Gm18776 MGI:MGI:5010961 +100417713 Gm15719 MGI:MGI:3783161 +100417714 Gm18777 MGI:MGI:5010962 +100417715 Rpap3-ps2 MGI:MGI:5010963 +100417717 Gm18779 MGI:MGI:5010964 +100417718 Gm18780 MGI:MGI:5010965 +100417719 Gm18781 MGI:MGI:5010966 +100417720 Gm18782 MGI:MGI:5010967 +100417721 Gm18783 MGI:MGI:5010968 +100417722 Gm21926 MGI:MGI:5439378 +100417723 Gm18784 MGI:MGI:5010969 +100417724 Gm18785 MGI:MGI:5010970 +100417725 Gm18786 MGI:MGI:5010971 +100417726 Gm18787 MGI:MGI:5010972 +100417727 Gm18788 MGI:MGI:5010973 +100417728 Gm18789 MGI:MGI:5010974 +100417729 Gm18790 MGI:MGI:5010975 +100417731 Gm18791 MGI:MGI:5010976 +100417732 Gm14128 MGI:MGI:3652218 +100417733 Gm18792 MGI:MGI:5010977 +100417734 Gm18793 MGI:MGI:5010978 +100417736 Gm18794 MGI:MGI:5010979 +100417737 Zfp36l1-ps MGI:MGI:3707318 +100417738 Gm18795 MGI:MGI:5010980 +100417739 Gm18796 MGI:MGI:5010981 +100417741 Gm18797 MGI:MGI:5010982 +100417743 Gm18798 MGI:MGI:5010983 +100417744 Gm18799 MGI:MGI:5010984 +100417745 Gm18800 MGI:MGI:5010985 +100417746 Gm18801 MGI:MGI:5010986 +100417747 Gm18802 MGI:MGI:5010987 +100417748 Gm18803 MGI:MGI:5010988 +100417749 Gm18804 MGI:MGI:5010989 +100417750 Gm18805 MGI:MGI:5010990 +100417751 Gm18806 MGI:MGI:5010991 +100417752 Gm18807 MGI:MGI:5010992 +100417753 Gm20950 MGI:MGI:5434305 +100417755 Gm18808 MGI:MGI:5010993 +100417756 Gm16580 MGI:MGI:4415000 +100417757 Gm18809 MGI:MGI:5010994 +100417758 Gm17222 MGI:MGI:4938049 +100417761 Gm18811 MGI:MGI:5010996 +100417762 Gm18812 MGI:MGI:5010997 +100417763 Gm3170 MGI:MGI:3781349 +100417764 Gm17046 MGI:MGI:4937873 +100417765 Gm17048 MGI:MGI:4937875 +100417766 Gm17045 MGI:MGI:4937872 +100417767 Gm3348 MGI:MGI:3781526 +100417768 Gm17121 MGI:MGI:4937948 +100417769 Gm18813 MGI:MGI:5010998 +100417770 Gm18814 MGI:MGI:5010999 +100417771 Gm18815 MGI:MGI:5011000 +100417772 Gm18816 MGI:MGI:5011001 +100417775 Gm12014 MGI:MGI:3651034 +100417776 Gm18817 MGI:MGI:5011002 +100417777 Gm18818 MGI:MGI:5011003 +100417778 Gm12509 MGI:MGI:3651361 +100417780 Gm18820 MGI:MGI:5011005 +100417781 Gm18821 MGI:MGI:5011006 +100417782 Gm18822 MGI:MGI:5011007 +100417783 Gm18823 MGI:MGI:5011008 +100417784 Gm18824 MGI:MGI:5011009 +100417785 Gm13677 MGI:MGI:3649765 +100417786 Gm15806 MGI:MGI:3802043 +100417787 Gm18825 MGI:MGI:5011010 +100417788 Gm18826 MGI:MGI:5011011 +100417790 Gm18827 MGI:MGI:5011012 +100417791 Gm18828 MGI:MGI:5011013 +100417792 Gm18829 MGI:MGI:5011014 +100417793 Gm18830 MGI:MGI:5011015 +100417794 Gm18831 MGI:MGI:5011016 +100417795 Gm18832 MGI:MGI:5011017 +100417797 Gm18833 MGI:MGI:5011018 +100417798 Gm18834 MGI:MGI:5011019 +100417799 Gm18835 MGI:MGI:5011020 +100417800 Gm18836 MGI:MGI:5011021 +100417801 Gm15667 MGI:MGI:3783109 +100417802 Gm18837 MGI:MGI:5011022 +100417804 Gm12419 MGI:MGI:3650581 +100417805 Gm18838 MGI:MGI:5011023 +100417806 Gm18839 MGI:MGI:5011024 +100417807 Gm18840 MGI:MGI:5011025 +100417808 Gm18841 MGI:MGI:5011026 +100417810 Gm18842 MGI:MGI:5011027 +100417811 Gm18843 MGI:MGI:5011028 +100417812 Gm18844 MGI:MGI:5011029 +100417813 Gm18845 MGI:MGI:5011030 +100417814 Gm13745 MGI:MGI:3651459 +100417815 Gm18846 MGI:MGI:5011031 +100417817 Gm18847 MGI:MGI:5011032 +100417818 LOC100417818 - +100417819 Gm14612 MGI:MGI:3705459 +100417820 Gm15379 MGI:MGI:3705643 +100417821 Gm14745 MGI:MGI:3705488 +100417822 Gm14802 MGI:MGI:3705570 +100417823 Gm18848 MGI:MGI:5011033 +100417825 Gm18849 MGI:MGI:5011034 +100417827 Gm18850 MGI:MGI:5011035 +100417828 Gm18851 MGI:MGI:5011036 +100417829 Gm17757 MGI:MGI:5009847|Ensembl:ENSMUSG00000099241 +100417831 Gm18853 MGI:MGI:5011038|Ensembl:ENSMUSG00000098934 +100417833 Gm18854 MGI:MGI:5011039 +100417834 Gm18855 MGI:MGI:5011040 +100417835 Gm18856 MGI:MGI:5011041 +100417836 Gm18857 MGI:MGI:5011042 +100417837 Gm18858 MGI:MGI:5011043 +100417838 Gm18859 MGI:MGI:5011044 +100417840 Gm18860 MGI:MGI:5011045 +100417841 Gm16204 MGI:MGI:3801788 +100417843 Gm12067 MGI:MGI:3649820 +100417844 Gm21927 MGI:MGI:5439379 +100417846 Gm12435 MGI:MGI:3651950 +100417847 Gm12687 MGI:MGI:3650435 +100417848 Gm11911 MGI:MGI:3650144 +100417850 Gm18861 MGI:MGI:5011046 +100417851 Gm18862 MGI:MGI:5011047 +100417852 Gm18863 MGI:MGI:5011048 +100417853 Gm18864 MGI:MGI:5011049 +100417854 Gm18865 MGI:MGI:5011050 +100417855 Gm8775 MGI:MGI:3646219 +100417856 Gm18866 MGI:MGI:5011051 +100417858 Gm18867 MGI:MGI:5011052 +100417859 Gm15263 MGI:MGI:3705753 +100417861 Gm14116 MGI:MGI:3651325 +100417862 Gm14153 MGI:MGI:3651343 +100417863 Gm18868 MGI:MGI:5011053 +100417864 Gm18869 MGI:MGI:5011054 +100417865 Gm18870 MGI:MGI:5011055 +100417867 Gm14774 MGI:MGI:3705616 +100417868 Gm14852 MGI:MGI:3705821 +100417871 Gm15048 MGI:MGI:3705330 +100417872 Gm15240 MGI:MGI:3705404 +100417873 Gm18871 MGI:MGI:5011056 +100417875 Gm18872 MGI:MGI:5011057 +100417876 Gm18873 MGI:MGI:5011058 +100417877 Gm18874 MGI:MGI:5011059 +100417878 Gm18875 MGI:MGI:5011060 +100417881 Gm18876 MGI:MGI:5011061 +100417882 Gm18877 MGI:MGI:5011062 +100417883 Gm18878 MGI:MGI:5011063 +100417884 Gm18879 MGI:MGI:5011064 +100417885 Gm18880 MGI:MGI:5011065 +100417886 Gm18881 MGI:MGI:5011066 +100417887 Gm18882 MGI:MGI:5011067 +100417888 Gm18883 MGI:MGI:5011068 +100417890 Gm18884 MGI:MGI:5011069 +100417891 Gm18885 MGI:MGI:5011070 +100417893 Gm18886 MGI:MGI:5011071 +100417894 Gm18887 MGI:MGI:5011072 +100417895 Gm18888 MGI:MGI:5011073 +100417896 Gm18889 MGI:MGI:5011074 +100417898 Gm18890 MGI:MGI:5011075 +100417899 Gm12598 MGI:MGI:3650482 +100417900 Gm11860 MGI:MGI:3649715 +100417901 Gm12961 MGI:MGI:3650787 +100417902 Gm13118 MGI:MGI:3651681 +100417903 Gm12393 MGI:MGI:3651009 +100417904 Gm18891 MGI:MGI:5011076 +100417905 Gm18892 MGI:MGI:5011077 +100417906 Gm16027 MGI:MGI:3801732 +100417907 Gm18893 MGI:MGI:5011078 +100417908 Gm17213 MGI:MGI:4938040 +100417909 Gm18894 MGI:MGI:5011079 +100417910 Gm18895 MGI:MGI:5011080 +100417911 Gm18896 MGI:MGI:5011081 +100417913 Gm18897 MGI:MGI:5011082 +100417914 Gm15049 MGI:MGI:3705647 +100417915 Gm14538 MGI:MGI:3705591 +100417917 Gm15367 MGI:MGI:3705658 +100417920 Gm14932 MGI:MGI:3705471 +100417921 Gm18898 MGI:MGI:5011083 +100417922 Gm18899 MGI:MGI:5011084 +100417923 Gm18900 MGI:MGI:5011085 +100417924 Gm20587 MGI:MGI:5295693 +100417925 Gm18901 MGI:MGI:5011086 +100417926 Gm18902 MGI:MGI:5011087 +100417927 Gm18903 MGI:MGI:5011088 +100417929 Gm18904 MGI:MGI:5011089 +100417930 Gm18905 MGI:MGI:5011090 +100417931 Gm18906 MGI:MGI:5011091 +100417932 Gm18907 MGI:MGI:5011092 +100417934 Gm9894 MGI:MGI:3642213 +100417936 Gm17190 MGI:MGI:4938017 +100417937 Gm18909 MGI:MGI:5011094 +100417938 Gm18910 MGI:MGI:5011095 +100417939 Gm18911 MGI:MGI:5011096 +100417941 Gm12369 MGI:MGI:3652093 +100417942 Gm12375 MGI:MGI:3652318 +100417943 Gm11254 MGI:MGI:3649979 +100417944 Gm18912 MGI:MGI:5011097 +100417945 Gm20951 MGI:MGI:5434306 +100417946 Gm18913 MGI:MGI:5011098 +100417947 Gm18914 MGI:MGI:5011099 +100417948 Pou5f1-rs9 MGI:MGI:101885 +100417950 Gm18916 MGI:MGI:5011101 +100417951 Gm18917 MGI:MGI:5011102 +100417952 Gm15897 MGI:MGI:3801942 +100417953 Gm18918 MGI:MGI:5011103 +100417955 Gm18919 MGI:MGI:5011104 +100417956 Gm14930 MGI:MGI:3705504 +100417957 Gm18920 MGI:MGI:5011105 +100417958 Gm14828 MGI:MGI:3708090 +100417959 Gm14985 MGI:MGI:3705725 +100417960 Gm18921 MGI:MGI:5011106 +100417962 Gm17052 MGI:MGI:4937879 +100417964 Gm15394 MGI:MGI:3705608 +100417965 Gm18922 MGI:MGI:5011107 +100417966 Gm18923 MGI:MGI:5011108 +100417967 Gm18924 MGI:MGI:5011109 +100417971 Gm18925 MGI:MGI:5011110 +100417972 Gm18926 MGI:MGI:5011111 +100417973 Pou5f1-rs6 MGI:MGI:101887 +100417974 Gm18928 MGI:MGI:5011113 +100417975 Gm20952 MGI:MGI:5434307 +100417976 Gm18929 MGI:MGI:5011114 +100417977 Gm16077 MGI:MGI:3802018 +100417978 Gm18930 MGI:MGI:5011115 +100417979 Gm18931 MGI:MGI:5011116 +100417980 Gm18932 MGI:MGI:5011117 +100417981 Gm18933 MGI:MGI:5011118 +100417982 Gm18934 MGI:MGI:5011119 +100417983 Gm20953 MGI:MGI:5434308 +100417984 LOC100417984 - +100417985 Gm18935 MGI:MGI:5011120 +100417987 Gm18936 MGI:MGI:5011121 +100417988 Gm12376 MGI:MGI:3651608 +100417989 Gm18937 MGI:MGI:5011122 +100417990 Gm20588 MGI:MGI:5295694 +100417991 Gm14281 MGI:MGI:3650417 +100417994 Gm15229 MGI:MGI:3644786 +100417995 Gm18938 MGI:MGI:5011123 +100417996 Gm14947 MGI:MGI:3642731 +100417998 Gm15225 MGI:MGI:3705585 +100417999 Gm18939 MGI:MGI:5011124 +100418000 Gm18940 MGI:MGI:5011125 +100418001 Gm20954 MGI:MGI:5434309 +100418002 Gm18941 MGI:MGI:5011126 +100418003 Rpl17-ps11 MGI:MGI:3802112 +100418004 Gm18942 MGI:MGI:5011127 +100418005 Gm15495 MGI:MGI:3782941 +100418006 Gm12782 MGI:MGI:3650361 +100418007 Gm18943 MGI:MGI:5011128 +100418009 Gm18944 MGI:MGI:5011129 +100418010 Gm18945 MGI:MGI:5011130 +100418012 Gm18947 MGI:MGI:5011132 +100418013 Gm18948 MGI:MGI:5011133 +100418014 Gm18949 MGI:MGI:5011134 +100418015 Gm2999 MGI:MGI:3781177 +100418016 Gm18950 MGI:MGI:5011135 +100418017 Gm20589 MGI:MGI:5295695 +100418019 Gm18951 MGI:MGI:5011136 +100418020 Gm20955 MGI:MGI:5434310 +100418022 Gm18952 MGI:MGI:5011137 +100418024 Gm11446 MGI:MGI:3651125 +100418025 Gm18953 MGI:MGI:5011138 +100418026 Gm15665 MGI:MGI:3783107 +100418027 Gm20956 MGI:MGI:5434311 +100418029 Gm18954 MGI:MGI:5011139 +100418030 Gm9202 MGI:MGI:3644604 +100418031 Gm18955 MGI:MGI:5011140 +100418032 Gm18956 MGI:MGI:5011141 +100418033 Gm18957 MGI:MGI:5011142 +100418035 Gm18958 MGI:MGI:5011143 +100418036 Gm8018 MGI:MGI:3645629 +100418037 Gm18959 MGI:MGI:5011144 +100418038 Gm18960 MGI:MGI:5011145 +100418039 Gm18961 MGI:MGI:5011146 +100418040 Gm18962 MGI:MGI:5011147 +100418041 Gm18963 MGI:MGI:5011148 +100418042 Gm12661 MGI:MGI:3650842 +100418043 Gm12492 MGI:MGI:3651196 +100418044 Gm12604 MGI:MGI:3651368 +100418045 Gm18964 MGI:MGI:5011149 +100418046 Gm18965 MGI:MGI:5011150 +100418047 Gm18966 MGI:MGI:5011151 +100418048 Gm15783 MGI:MGI:3783225 +100418049 Gm16274 MGI:MGI:3826552 +100418051 Gm18967 MGI:MGI:5011152 +100418053 Gm18968 MGI:MGI:5011153 +100418055 Gm18969 MGI:MGI:5011154 +100418056 Gm18970 MGI:MGI:5011155 +100418057 Gm18971 MGI:MGI:5011156 +100418058 Gm18972 MGI:MGI:5011157 +100418059 Gm18973 MGI:MGI:5011158 +100418060 Gm18974 MGI:MGI:5011159 +100418061 Gm18975 MGI:MGI:5011160 +100418062 Gm18976 MGI:MGI:5011161 +100418063 Gm18977 MGI:MGI:5011162 +100418064 Gm18978 MGI:MGI:5011163 +100418065 Gm18979 MGI:MGI:5011164 +100418066 Gm12202 MGI:MGI:3650184 +100418067 Gm11511 MGI:MGI:3649770 +100418068 Gm18980 MGI:MGI:5011165 +100418069 Gm18981 MGI:MGI:5011166 +100418070 Gm18982 MGI:MGI:5011167 +100418071 Gm13590 MGI:MGI:3650248 +100418072 Prkaca-ps1 MGI:MGI:97593 +100418073 Gm15021 MGI:MGI:3705348 +100418075 Gm18983 MGI:MGI:5011168 +100418076 Gm18984 MGI:MGI:5011169 +100418077 Gm18985 MGI:MGI:5011170 +100418078 Gm18986 MGI:MGI:5011171 +100418079 Gm18987 MGI:MGI:5011172 +100418080 Gm18988 MGI:MGI:5011173 +100418081 LOC100418081 - +100418082 Gm11282 MGI:MGI:3650570 +100418083 Gm18989 MGI:MGI:5011174 +100418084 Gm18990 MGI:MGI:5011175 +100418085 Gm18991 MGI:MGI:5011176 +100418086 Gm18992 MGI:MGI:5011177 +100418088 Gm18993 MGI:MGI:5011178 +100418089 Gm18994 MGI:MGI:5011179 +100418092 Gm13207 MGI:MGI:3651232 +100418095 Gm18995 MGI:MGI:5011180 +100418096 Gm18996 MGI:MGI:5011181 +100418097 Gm18997 MGI:MGI:5011182 +100418098 Gm18998 MGI:MGI:5011183 +100418099 Gm18999 MGI:MGI:5011184 +100418100 Gm19000 MGI:MGI:5011185 +100418101 Gm19001 MGI:MGI:5011186 +100418102 Gm19002 MGI:MGI:5011187 +100418103 Gm19003 MGI:MGI:5011188 +100418104 Gm38421 MGI:MGI:5621306 +100418105 Gm15372 MGI:MGI:3707469 +100418106 LOC100418106 - +100418107 Gm15371 MGI:MGI:3707464 +100418108 Gm15368 MGI:MGI:3707462 +100418109 Gm15376 MGI:MGI:3707460 +100418110 Gm19004 MGI:MGI:5011189 +100418111 Gm19005 MGI:MGI:5011190 +100418112 Gm19006 MGI:MGI:5011191 +100418113 Gm19007 MGI:MGI:5011192 +100418115 Gm19008 MGI:MGI:5011193 +100418116 Gm19009 MGI:MGI:5011194 +100418117 Gm19010 MGI:MGI:5011195 +100418118 Gm19011 MGI:MGI:5011196 +100418119 Gm19012 MGI:MGI:5011197 +100418120 Gm19013 MGI:MGI:5011198 +100418121 Gm19014 MGI:MGI:5011199 +100418122 Gm19015 MGI:MGI:5011200 +100418123 Gm19016 MGI:MGI:5011201 +100418124 Gm19017 MGI:MGI:5011202 +100418125 Gm19018 MGI:MGI:5011203 +100418126 Gm19019 MGI:MGI:5011204 +100418127 Gm19020 MGI:MGI:5011205 +100418129 Gm12825 MGI:MGI:3650153 +100418130 Gm19021 MGI:MGI:5011206 +100418131 Gm19022 MGI:MGI:5011207 +100418132 Gm19023 MGI:MGI:5011208 +100418133 Gm19024 MGI:MGI:5011209 +100418134 Gm13776 MGI:MGI:3650154 +100418136 Gm14908 MGI:MGI:3705416 +100418137 Gm19025 MGI:MGI:5011210 +100418138 Gm19026 MGI:MGI:5011211 +100418139 Gm19027 MGI:MGI:5011212 +100418140 Gm19028 MGI:MGI:5011213 +100418141 Gm19029 MGI:MGI:5011214 +100418142 Gm19030 MGI:MGI:5011215 +100418143 Gm19031 MGI:MGI:5011216 +100418144 Gm19032 MGI:MGI:5011217 +100418145 Gm19033 MGI:MGI:5011218 +100418148 Gm19034 MGI:MGI:5011219 +100418149 Gm19035 MGI:MGI:5011220 +100418151 Gm19037 MGI:MGI:5011222 +100418152 Gm19038 MGI:MGI:5011223 +100418153 Gm19039 MGI:MGI:5011224 +100418154 Gm19040 MGI:MGI:5011225 +100418155 Gm13615 MGI:MGI:3650493 +100418156 Gm13462 MGI:MGI:3649843 +100418157 Gm13517 MGI:MGI:3649620 +100418158 Gm19041 MGI:MGI:5011226 +100418159 Gm19042 MGI:MGI:5011227 +100418160 Gm19043 MGI:MGI:5011228 +100418161 Gm19044 MGI:MGI:5011229 +100418163 Gm19045 MGI:MGI:5011230 +100418164 Gm19046 MGI:MGI:5011231 +100418165 Gm19047 MGI:MGI:5011232 +100418166 Gm19048 MGI:MGI:5011233 +100418167 Kat6b-ps2 MGI:MGI:5011234 +100418168 Gm19050 MGI:MGI:5011235 +100418169 Gm19051 MGI:MGI:5011236 +100418170 Gm19052 MGI:MGI:5011237 +100418171 Gm19053 MGI:MGI:5011238 +100418172 Gm15967 MGI:MGI:3801808 +100418173 Gm19054 MGI:MGI:5011239 +100418175 Gm19055 MGI:MGI:5011240 +100418177 Gm14890 MGI:MGI:3802134 +100418178 Gm14898 MGI:MGI:3705749 +100418179 Gm19056 MGI:MGI:5011241 +100418180 Gm19057 MGI:MGI:5011242 +100418181 Gm19058 MGI:MGI:5011243 +100418182 Gm19059 MGI:MGI:5011244 +100418183 Gm19060 MGI:MGI:5011245 +100418184 Gm19061 MGI:MGI:5011246 +100418185 Gm19062 MGI:MGI:5011247 +100418186 Gm12314 MGI:MGI:3649316 +100418187 Gm11404 MGI:MGI:3651011 +100418189 Gm19063 MGI:MGI:5011248 +100418190 Gm19064 MGI:MGI:5011249 +100418191 Gm19065 MGI:MGI:5011250 +100418192 Gm17322 MGI:MGI:4936956 +100418193 Gm19066 MGI:MGI:5011251 +100418194 Gm19067 MGI:MGI:5011252 +100418195 Gm19068 MGI:MGI:5011253 +100418199 Gm19069 MGI:MGI:5011254 +100418200 Gm14849 MGI:MGI:3802125 +100418201 Gm19070 MGI:MGI:5011255 +100418203 Gm19071 MGI:MGI:5011256 +100418204 Gm19072 MGI:MGI:5011257 +100418205 Gm19073 MGI:MGI:5011258 +100418206 Gm19074 MGI:MGI:5011259 +100418210 Gm19075 MGI:MGI:5011260 +100418211 Gm16167 MGI:MGI:3802049 +100418212 Gm19076 MGI:MGI:5011261 +100418214 Gm19077 MGI:MGI:5011262 +100418216 Cyp4b1-ps1 MGI:MGI:3651921 +100418217 Gm12989 MGI:MGI:3652245 +100418218 Gm13899 MGI:MGI:3652262 +100418220 Gm19078 MGI:MGI:5011263 +100418221 Gm19079 MGI:MGI:5011264 +100418222 Gm19080 MGI:MGI:5011265 +100418223 Gm13260 MGI:MGI:3650840 +100418224 Gm19081 MGI:MGI:5011266 +100418225 Gm19082 MGI:MGI:5011267 +100418226 Gm19083 MGI:MGI:5011268 +100418227 Gm19084 MGI:MGI:5011269 +100418228 Gm17031 MGI:MGI:4937858 +100418229 Gm19085 MGI:MGI:5011270 +100418230 Gm19086 MGI:MGI:5011271 +100418231 Gm19087 MGI:MGI:5011272 +100418232 Gm19088 MGI:MGI:5011273 +100418234 Gm19089 MGI:MGI:5011274 +100418235 C130030K03Rik MGI:MGI:2444432 +100418236 Gm19090 MGI:MGI:5011275 +100418238 Gm19091 MGI:MGI:5011276 +100418239 Gm19092 MGI:MGI:5011277 +100418240 Gm19093 MGI:MGI:5011278 +100418241 Gm19094 MGI:MGI:5011279 +100418242 Gm19095 MGI:MGI:5011280 +100418243 Gm19096 MGI:MGI:5011281 +100418247 Gm19097 MGI:MGI:5011282 +100418248 Gm19098 MGI:MGI:5011283 +100418249 Gm19099 MGI:MGI:5011284 +100418251 Gm19100 MGI:MGI:5011285 +100418252 Gm20957 MGI:MGI:5434312 +100418253 Cyp2d67-ps MGI:MGI:5011286 +100418254 Gm11637 MGI:MGI:3651875 +100418256 Gm19102 MGI:MGI:5011287 +100418257 Gm19103 MGI:MGI:5011288 +100418258 Gm19104 MGI:MGI:5011289 +100418259 Gm14117 MGI:MGI:3651328 +100418260 Gm19105 MGI:MGI:5011290 +100418262 Gm19106 MGI:MGI:5011291 +100418263 Gm19107 MGI:MGI:5011292 +100418265 Gm19108 MGI:MGI:5011293 +100418268 Gm19109 MGI:MGI:5011294 +100418269 Cyp2d34-ps MGI:MGI:5011295 +100418271 Gm19111 MGI:MGI:5011296 +100418274 Gm19112 MGI:MGI:5011297 +100418276 Gm19113 MGI:MGI:5011298 +100418280 Gm19114 MGI:MGI:5011299 +100418281 Gm19115 MGI:MGI:5011300 +100418282 Gm19116 MGI:MGI:5011301 +100418283 Gm17514 MGI:MGI:4937148 +100418284 Gm19117 MGI:MGI:5011302 +100418285 Gm20590 MGI:MGI:5295696 +100418286 Gm19118 MGI:MGI:5011303 +100418287 Gm19119 MGI:MGI:5011304 +100418288 Skiv2l-ps1 MGI:MGI:2148492 +100418289 Gm19120 MGI:MGI:5011305 +100418290 Gm19121 MGI:MGI:5011306 +100418291 Gm13444 MGI:MGI:3649616 +100418292 Gm14917 MGI:MGI:3712369 +100418293 Gm14910 MGI:MGI:3705414 +100418294 Gm19122 MGI:MGI:5011307 +100418295 Gm19123 MGI:MGI:5011308 +100418296 Gm19124 MGI:MGI:5011309 +100418297 Gm19125 MGI:MGI:5011310 +100418298 Gm19126 MGI:MGI:5011311 +100418299 Gm19127 MGI:MGI:5011312 +100418301 Gm19129 MGI:MGI:5011314 +100418302 LOC100418302 - +100418303 Gm19130 MGI:MGI:5011315 +100418304 Gm11875 MGI:MGI:3649519 +100418306 Gm19131 MGI:MGI:5011316 +100418307 Gm19132 MGI:MGI:5011317 +100418309 Gm19133 MGI:MGI:5011318 +100418310 Gm15953 MGI:MGI:3802150 +100418311 Gm14800 MGI:MGI:3705352 +100418312 Gm14912 MGI:MGI:3705628 +100418313 Gm14896 MGI:MGI:3705722 +100418314 Gm14914 MGI:MGI:3705473 +100418315 Gm19134 MGI:MGI:5011319 +100418316 Gm19135 MGI:MGI:5011320 +100418317 Gm16107 MGI:MGI:3801820 +100418318 Gm19136 MGI:MGI:5011321 +100418319 Gm19137 MGI:MGI:5011322 +100418320 Gm19138 MGI:MGI:5011323 +100418321 Gm19139 MGI:MGI:5011324 +100418322 Gm19140 MGI:MGI:5011325 +100418323 Gm19141 MGI:MGI:5011326 +100418324 LOC100418324 - +100418325 Gm12010 MGI:MGI:3651312 +100418326 Gm12978 MGI:MGI:3705382 +100418327 Gm16353 MGI:MGI:3840136 +100418328 Gm16215 MGI:MGI:3801727 +100418329 Gm14048 MGI:MGI:3650660 +100418330 Gm19142 MGI:MGI:5011327 +100418331 Gm19143 MGI:MGI:5011328 +100418332 Gm19144 MGI:MGI:5011329 +100418333 Gm19145 MGI:MGI:5011330 +100418334 Gm19146 MGI:MGI:5011331 +100418335 Gm15937 MGI:MGI:3802031 +100418337 Gm19147 MGI:MGI:5011332 +100418338 Gm19148 MGI:MGI:5011333 +100418339 Gm19149 MGI:MGI:5011334 +100418340 Gm13732 MGI:MGI:3650014 +100418341 Gm11743 MGI:MGI:3651178 +100418342 Gm19150 MGI:MGI:5011335 +100418343 Gm19151 MGI:MGI:5011336 +100418344 Gm19152 MGI:MGI:5011337 +100418345 Gm14589 MGI:MGI:3705493 +100418346 Gm14678 MGI:MGI:3705614 +100418347 Gm14677 MGI:MGI:3705464 +100418348 Gm19153 MGI:MGI:5011338 +100418349 Gm19154 MGI:MGI:5011339 +100418350 Gm19155 MGI:MGI:5011340 +100418352 Gm19156 MGI:MGI:5011341 +100418353 Gm19157 MGI:MGI:5011342 +100418354 Gm19158 MGI:MGI:5011343 +100418355 Gm19159 MGI:MGI:5011344 +100418356 Gm12096 MGI:MGI:3651583 +100418357 Gm12734 MGI:MGI:3650213 +100418358 Gm19160 MGI:MGI:5011345 +100418359 Gm19161 MGI:MGI:5011346 +100418360 Gm19162 MGI:MGI:5011347 +100418361 Gm19163 MGI:MGI:5011348 +100418363 Gm11394 MGI:MGI:3649833 +100418364 Gm11279 MGI:MGI:3651909 +100418365 Gm19164 MGI:MGI:5011349 +100418366 Gm12361 MGI:MGI:3652291 +100418367 Gm13223 MGI:MGI:3652163 +100418368 Gm13036 MGI:MGI:3650250 +100418369 Gm19165 MGI:MGI:5011350 +100418370 Gm19166 MGI:MGI:5011351 +100418372 Gm17076 MGI:MGI:4937903 +100418373 Gm19167 MGI:MGI:5011352 +100418374 Gm17042 MGI:MGI:4937869 +100418375 Gm17043 MGI:MGI:4937870 +100418376 Gm17198 MGI:MGI:4938025 +100418377 Gm19168 MGI:MGI:5011353 +100418378 Gm19169 MGI:MGI:5011354 +100418379 Gm19170 MGI:MGI:5011355 +100418380 Gm19171 MGI:MGI:5011356 +100418381 Gm16209 MGI:MGI:3802095 +100418382 Gm19172 MGI:MGI:5011357 +100418383 Gm19173 MGI:MGI:5011358 +100418384 Gm19174 MGI:MGI:5011359 +100418385 Gm19175 MGI:MGI:5011360 +100418386 Gm19176 MGI:MGI:5011361 +100418387 Gm11896 MGI:MGI:3651205 +100418388 Gm19177 MGI:MGI:5011362 +100418389 Gm19178 MGI:MGI:5011363 +100418390 Gm19179 MGI:MGI:5011364 +100418391 Gm19180 MGI:MGI:5011365 +100418393 Gm19181 MGI:MGI:5011366 +100418394 Gm19182 MGI:MGI:5011367 +100418395 Gm19183 MGI:MGI:5011368 +100418396 Gm12220 MGI:MGI:3649331 +100418399 Gm19184 MGI:MGI:5011369 +100418400 Pafah1b1-ps2 MGI:MGI:103109 +100418401 Gm19185 MGI:MGI:5011370 +100418403 Gm19186 MGI:MGI:5011371 +100418404 Gm19187 MGI:MGI:5011372 +100418406 Gm19189 MGI:MGI:5011374 +100418407 Gm19190 MGI:MGI:5011375 +100418408 Gm14647 MGI:MGI:3705420 +100418409 Gm19191 MGI:MGI:5011376 +100418410 Gm2987 MGI:MGI:3781165 +100418411 Gm19192 MGI:MGI:5011377 +100418412 Gm19193 MGI:MGI:5011378 +100418413 Gm19194 MGI:MGI:5011379 +100418414 Gm19195 MGI:MGI:5011380 +100418415 Gm19196 MGI:MGI:5011381 +100418416 Gm19197 MGI:MGI:5011382 +100418417 Gm19198 MGI:MGI:5011383 +100418418 Gm19199 MGI:MGI:5011384 +100418419 Gm12451 MGI:MGI:3649963 +100418420 Gm19200 MGI:MGI:5011385 +100418421 Gm19201 MGI:MGI:5011386 +100418422 Gm19202 MGI:MGI:5011387 +100418423 Gm19203 MGI:MGI:5011388 +100418424 Gm19204 MGI:MGI:5011389 +100418426 Gm19205 MGI:MGI:5011390 +100418427 Gm19206 MGI:MGI:5011391 +100418428 Gm19207 MGI:MGI:5011392 +100418429 Gm19208 MGI:MGI:5011393 +100418430 Gm19209 MGI:MGI:5011394 +100418432 Gm19210 MGI:MGI:5011395 +100418433 Gm19211 MGI:MGI:5011396 +100418434 Gm12399 MGI:MGI:3651917 +100418436 Gm12653 MGI:MGI:3650062 +100418437 Gm19212 MGI:MGI:5011397 +100418438 Gm19213 MGI:MGI:5011398 +100418440 Gm12656 MGI:MGI:3651715 +100418441 Gm19214 MGI:MGI:5011399 +100418442 Gm19215 MGI:MGI:5011400 +100418444 Gm19216 MGI:MGI:5011401 +100418445 Gm19217 MGI:MGI:5011402 +100418446 Gm19218 MGI:MGI:5011403 +100418447 Gm13316 MGI:MGI:3651097 +100418448 Gm14274 MGI:MGI:3649603 +100418450 Gm12803 MGI:MGI:3651634 +100418451 Gm19219 MGI:MGI:5011404 +100418452 Gm19220 MGI:MGI:5011405 +100418453 Gm19221 MGI:MGI:5011406 +100418454 Gm19222 MGI:MGI:5011407 +100418456 Gm19223 MGI:MGI:5011408 +100418457 Gm11871 MGI:MGI:3649332 +100418458 Gm19224 MGI:MGI:5011409 +100418459 Gm19225 MGI:MGI:5011410 +100418460 Gm4202 MGI:MGI:3782379 +100418461 Gm19226 MGI:MGI:5011411 +100418462 Gm19227 MGI:MGI:5011412 +100418463 Gm19228 MGI:MGI:5011413 +100418465 Gm4728 MGI:MGI:3782908 +100418466 Gm11606 MGI:MGI:3649658 +100418467 Gm19229 MGI:MGI:5011414 +100418468 Gm19230 MGI:MGI:5011415 +100418470 Gm17205 MGI:MGI:4938032 +100418471 Gm19231 MGI:MGI:5011416 +100418472 Gm19232 MGI:MGI:5011417 +100418475 Gm19233 MGI:MGI:5011418 +100418476 Gm19234 MGI:MGI:5011419 +100418477 Gm19235 MGI:MGI:5011420 +100418478 Gm19236 MGI:MGI:5011421 +100418479 Gm19237 MGI:MGI:5011422 +100418480 Gm19238 MGI:MGI:5011423 +100418481 Gm19239 MGI:MGI:5011424 +100418482 Gm19240 MGI:MGI:5011425 +100418483 Gm19241 MGI:MGI:5011426 +100422782 Gm14607 MGI:MGI:3710229 +100422783 Gm11786 MGI:MGI:3649460 +100422784 Gm12752 MGI:MGI:3650845 +100422785 Gm12754 MGI:MGI:3651052 +100422786 Gm11242 MGI:MGI:3652117 +100422787 Gm15102 MGI:MGI:3705854 +100423045 Gm10772 MGI:MGI:3704404 +100462662 Gm14226 MGI:MGI:3649244 +100462664 Krtap29-1 MGI:MGI:3652056 +100462728 Rps27-ps1 MGI:MGI:3652266 +100462729 Gm14175 MGI:MGI:3650264 +100462730 Gm11456 MGI:MGI:3652038 +100462734 Gm19242 MGI:MGI:5011427 +100462736 Gm19243 MGI:MGI:5011428 +100462737 Gm19244 MGI:MGI:5011429 +100462738 Gm19245 MGI:MGI:5011430 +100462739 Gm19246 MGI:MGI:5011431 +100462740 Gm19247 MGI:MGI:5011432 +100462741 Gm17241 MGI:MGI:4936875 +100462895 Gm13350 MGI:MGI:3651066 +100462931 Gm13588 MGI:MGI:3650686 +100462932 Gm19248 MGI:MGI:5011433 +100462933 Gm19249 MGI:MGI:5011434 +100462934 Gm19250 MGI:MGI:5011435 +100462935 Gm19251 MGI:MGI:5011436 +100462950 Gm10332 MGI:MGI:3642276 +100462955 Gm13687 MGI:MGI:3651822 +100462956 Gm19252 MGI:MGI:5011437 +100462958 Gm19253 MGI:MGI:5011438 +100462959 Gm19254 MGI:MGI:5011439 +100462960 Mrps36-ps3 MGI:MGI:5011440 +100462961 Gm16149 MGI:MGI:3801828 +100462962 Gm11689 MGI:MGI:3652327 +100462963 Gm16260 MGI:MGI:3826596 +100462966 Gm19256 MGI:MGI:5011441 +100462980 Gm19257 MGI:MGI:5011442 +100463507 Gm20591 MGI:MGI:5295697 +100463508 Gm19258 MGI:MGI:5011443 +100463509 Gm20592 MGI:MGI:5295698 +100463510 Gm20593 MGI:MGI:5295699 +100463511 Gm19259 MGI:MGI:5011444 +100463512 Gm20594 MGI:MGI:5295700|Ensembl:ENSMUSG00000096887|Vega:OTTMUSG00000057744 +100463513 Gm19260 MGI:MGI:5011445 +100463514 Gm20595 MGI:MGI:5295701 +100463519 BB283400 MGI:MGI:3034268 +100463526 Gm17192 MGI:MGI:4938019 +100463527 Gm20596 MGI:MGI:5295702 +100499160 Gm20958 MGI:MGI:5434313 +100499512 Mir3475 MGI:MGI:4441442|Ensembl:ENSMUSG00000093102|miRBase:MI0004220 +100499513 Mir3099 MGI:MGI:4441433|Ensembl:ENSMUSG00000092815|miRBase:MI0004485 +100499514 Mir2861 MGI:MGI:4441431|Ensembl:ENSMUSG00000093280|miRBase:MI0013007 +100499517 Mir3072 MGI:MGI:4441432|Ensembl:ENSMUSG00000093351|miRBase:MI0014035 +100499518 Mir3470a MGI:MGI:4441434|Ensembl:ENSMUSG00000095323|miRBase:MI0014696 +100499519 Mir3470b MGI:MGI:4441435|Ensembl:ENSMUSG00000093912|miRBase:MI0014697 +100499521 Mir3471-1 MGI:MGI:4441436|Ensembl:ENSMUSG00000092880|miRBase:MI0014699 +100499523 Mir3471-2 MGI:MGI:4441437|Ensembl:ENSMUSG00000094253|miRBase:MI0014701 +100499526 Mir3472 MGI:MGI:4441439|Ensembl:ENSMUSG00000092917|miRBase:MI0014704 +100499528 Mir3473a MGI:MGI:4441440|Ensembl:ENSMUSG00000092752|miRBase:MI0014706 +100499529 Mir3474 MGI:MGI:4441441|Ensembl:ENSMUSG00000093120|miRBase:MI0014707 +100499530 Mir1906-2 MGI:MGI:4441422|Ensembl:ENSMUSG00000084559|miRBase:MI0015984 +100500713 9530027J09Rik MGI:MGI:4820557|Ensembl:ENSMUSG00000097197 +100500796 Stc7-1 - +100502579 Gm19261 MGI:MGI:5011446 +100502580 LOC100502580 - +100502582 Gm10923 MGI:MGI:3779135 +100502584 Gm19264 MGI:MGI:5011449 +100502585 Gm14903 MGI:MGI:3705556 +100502586 Gm19265 MGI:MGI:5011450 +100502587 Fkbp1a-ps1 MGI:MGI:108477 +100502588 Gm16545 MGI:MGI:4414965 +100502589 Gm19267 MGI:MGI:5011452 +100502590 Tex50 MGI:MGI:1922183 +100502592 LOC100502592 - +100502593 Gm19269 MGI:MGI:5011454 +100502597 Gm19272 MGI:MGI:5011457 +100502599 Gm19274 MGI:MGI:5011459 +100502601 Gm19276 MGI:MGI:5011461 +100502602 Gm19277 MGI:MGI:5011462 +100502606 Gm19279 MGI:MGI:5011464 +100502607 Gm19280 MGI:MGI:5011465 +100502608 Gm15200 MGI:MGI:3705136 +100502609 Gm11386 MGI:MGI:3649585 +100502610 Gm19281 MGI:MGI:5011466 +100502612 Gm19283 MGI:MGI:5011468 +100502616 Gm12787 MGI:MGI:3650112 +100502617 Gm19287 MGI:MGI:5011472 +100502618 Gm19288 MGI:MGI:5011473 +100502619 AW046200 MGI:MGI:2142745 +100502621 Gm19290 MGI:MGI:5011475 +100502622 Gm19291 MGI:MGI:5011476 +100502624 Gm13483 MGI:MGI:3651423|Ensembl:ENSMUSG00000085862 +100502625 Gm19293 MGI:MGI:5011478 +100502628 Gm19295 MGI:MGI:5011480 +100502629 Gm12726 MGI:MGI:3649291 +100502630 Gm15545 MGI:MGI:3782994|Ensembl:ENSMUSG00000087138 +100502631 Rps19-ps11 MGI:MGI:4414982 +100502633 Gm19297 MGI:MGI:5011482 +100502635 Gm11525 MGI:MGI:3651809 +100502636 Gm19299 MGI:MGI:5011484|Ensembl:ENSMUSG00000111556 +100502637 Gm19300 MGI:MGI:5011485 +100502638 Gm19301 MGI:MGI:5011486 +100502641 Gm17511 MGI:MGI:4937145 +100502643 Gm19303 MGI:MGI:5011488 +100502644 AA419673 MGI:MGI:2139579 +100502647 Gm11583 MGI:MGI:3705153 +100502648 Gm19304 MGI:MGI:5011489 +100502649 Gm17396 MGI:MGI:4937030 +100502650 Gm11997 MGI:MGI:3650899 +100502653 C130060C02Rik MGI:MGI:3041192|Ensembl:ENSMUSG00000097557 +100502654 Gm11474 MGI:MGI:3652276 +100502655 Gm19306 MGI:MGI:5011491 +100502657 Gm19308 MGI:MGI:5011493 +100502659 Gm17522 MGI:MGI:4937156 +100502661 Gm15527 MGI:MGI:3782974 +100502662 Gm15925 MGI:MGI:3801830 +100502664 Gm19309 MGI:MGI:5011494 +100502666 Gm19311 MGI:MGI:5011496 +100502667 Gm19312 MGI:MGI:5011497 +100502668 Gm19313 MGI:MGI:5011498 +100502670 Gm16010 MGI:MGI:3802126 +100502671 Gm19314 MGI:MGI:5011499 +100502673 Gm19316 MGI:MGI:5011501 +100502678 Gm12187 MGI:MGI:3651944 +100502679 Gm15577 MGI:MGI:3783025 +100502680 Gm10015 MGI:MGI:3809114 +100502682 Gm19320 MGI:MGI:5011505 +100502683 Gm2581 MGI:MGI:3780749 +100502684 Gm20621 MGI:MGI:5313068 +100502686 Gm15946 MGI:MGI:3801999 +100502689 Gm11218 MGI:MGI:3651636 +100502690 Gm12638 MGI:MGI:3650765 +100502691 Gm11633 MGI:MGI:3650676 +100502693 Gm19324 MGI:MGI:5011509 +100502694 Gm19325 MGI:MGI:5011510 +100502695 Gm17399 MGI:MGI:4937033|Ensembl:ENSMUSG00000097402 +100502696 Gm19326 MGI:MGI:5011511 +100502697 Gm19327 MGI:MGI:5011512 +100502698 Rubcn MGI:MGI:1915160|Ensembl:ENSMUSG00000035629|Vega:OTTMUSG00000026856 +100502700 AV039307 MGI:MGI:2139243|Ensembl:ENSMUSG00000087519 +100502701 Gm14768 MGI:MGI:3705522 +100502704 Gm19331 MGI:MGI:5011516 +100502707 Gm14945 MGI:MGI:3705383 +100502710 Gm19334 MGI:MGI:5011519 +100502712 Gm19335 MGI:MGI:5011520 +100502713 Gm13541 MGI:MGI:3651925 +100502716 Gm17267 MGI:MGI:4936901 +100502720 Gm16144 MGI:MGI:3801782 +100502721 Gm19337 MGI:MGI:5011522 +100502723 Tsga8 MGI:MGI:1194903|Ensembl:ENSMUSG00000035522|Vega:OTTMUSG00000017933 +100502727 Gm19340 MGI:MGI:5011525 +100502732 Gm19343 MGI:MGI:5011528 +100502733 Gm19344 MGI:MGI:5011529 +100502734 Gm16023 MGI:MGI:3802146|Ensembl:ENSMUSG00000086682 +100502736 Gm19345 MGI:MGI:5011530|Ensembl:ENSMUSG00000092216|Vega:OTTMUSG00000037671 +100502738 9030411K21Rik MGI:MGI:1918807 +100502739 Gm17509 MGI:MGI:4937143 +100502740 4930423K06Rik MGI:MGI:1921890 +100502742 1700007L15Rik MGI:MGI:1916581|Ensembl:ENSMUSG00000097318 +100502743 Gm13369 MGI:MGI:3651010 +100502745 2900009J06Rik MGI:MGI:1920137|Ensembl:ENSMUSG00000102014 +100502746 Gm15607 MGI:MGI:3783054 +100502750 Gm19351 MGI:MGI:5011536 +100502751 Gm17251 MGI:MGI:4936885 +100502752 A130015J22Rik MGI:MGI:2443821 +100502754 Gm12355 MGI:MGI:3649769 +100502756 Gm19353 MGI:MGI:5011538 +100502757 Gm17259 MGI:MGI:4936893 +100502761 Gm13820 MGI:MGI:3650427 +100502762 Gm12217 MGI:MGI:3649337 +100502763 Prox2os MGI:MGI:5011542 +100502764 Gm16617 MGI:MGI:4439541|Ensembl:ENSMUSG00000097633 +100502766 Kifc1 MGI:MGI:109596|Ensembl:ENSMUSG00000079553|Vega:OTTMUSG00000037214 +100502767 5230400M03Rik MGI:MGI:3026996 +100502768 Gm19359 MGI:MGI:5011544 +100502775 Gm15609 MGI:MGI:3783055 +100502777 Gm38422 MGI:MGI:5621307 +100502779 Gm12356 MGI:MGI:3651195 +100502780 Gm19366 MGI:MGI:5011551 +100502782 Gm19368 MGI:MGI:5011553 +100502785 Gm19371 MGI:MGI:5011556 +100502787 Gm19373 MGI:MGI:5011558 +100502788 Gm13821 MGI:MGI:3652003 +100502789 Gm17552 MGI:MGI:4937186 +100502790 Gm12239 MGI:MGI:3651547 +100502792 Gm19374 MGI:MGI:5011559 +100502794 Gm19376 MGI:MGI:5011561 +100502796 Gm19378 MGI:MGI:5011563 +100502800 Gm19382 MGI:MGI:5011567 +100502801 Gm19383 MGI:MGI:5011568 +100502803 Gm11562 MGI:MGI:3652059|Ensembl:ENSMUSG00000062278|Vega:OTTMUSG00000002199 +100502804 Gm15744 MGI:MGI:3783186 +100502807 Gm19385 MGI:MGI:5011570 +100502808 Gm19386 MGI:MGI:5011571 +100502813 Gm19391 MGI:MGI:5011576 +100502814 Zfp989 MGI:MGI:3651739 +100502819 BC065403 MGI:MGI:3697430|Ensembl:ENSMUSG00000097211 +100502820 Gm19395 MGI:MGI:5011580|Ensembl:ENSMUSG00000112709 +100502824 Gm19399 MGI:MGI:5011584 +100502825 Rpl37rt MGI:MGI:3651519 +100502828 Gm19401 MGI:MGI:5011586 +100502829 Gm9899 MGI:MGI:3708711|Ensembl:ENSMUSG00000053214 +100502831 Gm19402 MGI:MGI:5011587|Ensembl:ENSMUSG00000095970 +100502834 Gm15972 MGI:MGI:3801965|Ensembl:ENSMUSG00000086287 +100502841 Epg5 MGI:MGI:1918673|Ensembl:ENSMUSG00000039840 +100502842 Gm14718 MGI:MGI:3705113|Ensembl:ENSMUSG00000085808 +100502845 Gm19409 MGI:MGI:5011594 +100502846 Gm19410 MGI:MGI:5011595|Ensembl:ENSMUSG00000109372|Vega:OTTMUSG00000059262 +100502849 Gm19412 MGI:MGI:5011597 +100502853 Gm14002 MGI:MGI:3650401 +100502854 D030029J20Rik MGI:MGI:2139307 +100502856 Gm15848 MGI:MGI:3802054 +100502857 Gm19417 MGI:MGI:5011602 +100502858 Gm19418 MGI:MGI:5011603 +100502859 Mrgprx3-ps MGI:MGI:2685506 +100502861 Ccdc13 MGI:MGI:1920144|Ensembl:ENSMUSG00000079235|Vega:OTTMUSG00000034148 +100502862 Gm14710 MGI:MGI:3642278 +100502864 Gm15756 MGI:MGI:3783199 +100502865 2300003K06Rik MGI:MGI:1916701|Ensembl:ENSMUSG00000078257|Vega:OTTMUSG00000002197 +100502866 Gm20963 MGI:MGI:5434318 +100502868 Gm20597 MGI:MGI:5295703|Ensembl:ENSMUSG00000112739 +100502869 Gm19422 MGI:MGI:5011607 +100502871 Gm19424 MGI:MGI:5011609 +100502874 Gm19426 MGI:MGI:5011611 +100502875 Gm12676 MGI:MGI:3651064 +100502876 Kcnmb3 MGI:MGI:3612244|Ensembl:ENSMUSG00000091091|Vega:OTTMUSG00000052054 +100502877 Rps8-ps4 MGI:MGI:3809043 +100502879 Gm19427 MGI:MGI:5011612 +100502880 Gm19428 MGI:MGI:5011613 +100502882 Gm19430 MGI:MGI:5011615 +100502887 Olfr331 MGI:MGI:3030165|Ensembl:ENSMUSG00000058807|Vega:OTTMUSG00000005741 +100502888 Gm19434 MGI:MGI:5011619|Ensembl:ENSMUSG00000108239 +100502892 Gm19437 MGI:MGI:5011622 +100502895 Gm19439 MGI:MGI:5011624 +100502896 Gm11238 MGI:MGI:3702316 +100502897 Gm12854 MGI:MGI:3650410 +100502898 Gm19440 MGI:MGI:5011625 +100502899 Gm10807 MGI:MGI:3798168 +100502900 Gm19441 MGI:MGI:5011626 +100502902 Gm19443 MGI:MGI:5011628 +100502903 Gm19444 MGI:MGI:5011629 +100502904 Gm19445 MGI:MGI:5011630 +100502906 Gm19446 MGI:MGI:5011631 +100502908 Gm12034 MGI:MGI:3651409 +100502909 Gm19448 MGI:MGI:5011633 +100502910 Gm19449 MGI:MGI:5011634 +100502912 Gm17315 MGI:MGI:4936949 +100502913 Gm16244 MGI:MGI:3802128 +100502914 Gm19451 MGI:MGI:5011636 +100502916 Gm26989 MGI:MGI:5504104 +100502917 Gm12130 MGI:MGI:3651512 +100502920 Gm16998 MGI:MGI:4439922|Ensembl:ENSMUSG00000097069 +100502921 Gm10142 MGI:MGI:3641725|Ensembl:ENSMUSG00000094146 +100502923 Gm17619 MGI:MGI:4937253|Ensembl:ENSMUSG00000097514 +100502924 Gm38423 MGI:MGI:5621308 +100502926 Gm19457 MGI:MGI:5011642 +100502928 9430032J07Rik MGI:MGI:1924523 +100502931 Gm15821 MGI:MGI:3801940 +100502932 Gm13544 MGI:MGI:3649668|Ensembl:ENSMUSG00000086995 +100502933 Gm19461 MGI:MGI:5011646|Ensembl:ENSMUSG00000101693 +100502934 Gm13842 MGI:MGI:3650892 +100502936 E330021D16Rik MGI:MGI:2141773|Ensembl:ENSMUSG00000045291|Vega:OTTMUSG00000057217 +100502937 Gm19463 MGI:MGI:5011648|Ensembl:ENSMUSG00000030930 +100502938 Gm17491 MGI:MGI:4937125 +100502940 Colca2 MGI:MGI:2685530|Ensembl:ENSMUSG00000079559|Vega:OTTMUSG00000063082 +100502941 Gm17353 MGI:MGI:4936987 +100502942 Gm4814 MGI:MGI:3647983 +100502944 Gm19465 MGI:MGI:5011650 +100502945 Gm19466 MGI:MGI:5011651 +100502946 Gm16796 MGI:MGI:4439720|Ensembl:ENSMUSG00000085495 +100502949 Gm11626 MGI:MGI:3699632 +100502950 Gm3336 MGI:MGI:3781514|Ensembl:ENSMUSG00000095026|Vega:OTTMUSG00000061543 +100502952 Gm9775 MGI:MGI:3809039 +100502953 Gm10100 MGI:MGI:3642388|Ensembl:ENSMUSG00000096421 +100502954 Gm19469 MGI:MGI:5011654 +100502955 Gm19470 MGI:MGI:5011655 +100502956 Gm19471 MGI:MGI:5011656 +100502959 AV051173 MGI:MGI:3034405 +100502960 Gm19474 MGI:MGI:5011659 +100502967 Speer4c MGI:MGI:1914023|Ensembl:ENSMUSG00000073208|Vega:OTTMUSG00000031852 +100502971 Gm19479 MGI:MGI:5011664 +100502972 Gm19480 MGI:MGI:5011665 +100502973 Gm12996 MGI:MGI:3650481 +100502978 Gm19484 MGI:MGI:5011669 +100502979 Gm17546 MGI:MGI:4937180 +100502981 Gm19486 MGI:MGI:5011671 +100502982 BC037704 MGI:MGI:2652856 +100502983 Gm11407 MGI:MGI:3651131 +100502985 Gm10814 MGI:MGI:3642580|Ensembl:ENSMUSG00000097404 +100502987 Gm17066 MGI:MGI:4937893 +100502993 Gm19492 MGI:MGI:5011677 +100502995 Gm19494 MGI:MGI:5011679 +100502998 Gm15211 MGI:MGI:3705544 +100502999 Gm19497 MGI:MGI:5011682 +100503000 Zfp993 MGI:MGI:3713585 +100503002 Gm38424 MGI:MGI:5621309 +100503003 Gm17484 MGI:MGI:4937118 +100503004 Gm19498 MGI:MGI:5011683 +100503007 Gm19500 MGI:MGI:5011685 +100503008 Gm19501 MGI:MGI:5011686 +100503010 Gm19502 MGI:MGI:5011687 +100503011 Gm11410 MGI:MGI:3652015 +100503012 Gm19503 MGI:MGI:5011688 +100503014 Gm19505 MGI:MGI:5011690 +100503017 Gm11628 MGI:MGI:3651276 +100503019 Gm16551 MGI:MGI:4414971|Ensembl:ENSMUSG00000066477 +100503021 Gm19510 MGI:MGI:5011695 +100503023 Gm12843 MGI:MGI:3651051 +100503026 Gm19514 MGI:MGI:5011699 +100503032 Mark1-ps3 MGI:MGI:5011703 +100503033 Gm19519 MGI:MGI:5011704 +100503034 Gm15228 MGI:MGI:3705118 +100503036 1700015G11Rik MGI:MGI:1922779|Ensembl:ENSMUSG00000094445|Vega:OTTMUSG00000045112 +100503038 Gm19521 MGI:MGI:5011706 +100503040 Gm19522 MGI:MGI:5011707 +100503041 Pdzd7 MGI:MGI:3608325|Ensembl:ENSMUSG00000074818|Vega:OTTMUSG00000033081 +100503043 Armcx4 MGI:MGI:2147887|Ensembl:ENSMUSG00000049804|Vega:OTTMUSG00000019428 +100503044 A730020M07Rik MGI:MGI:2442643|Ensembl:ENSMUSG00000044522 +100503046 Gm14963 MGI:MGI:3705162 +100503047 LOC100503047 - +100503048 LOC100503048 - +100503050 Rapgef3os2 MGI:MGI:3826581 +100503053 Gm14517 MGI:MGI:3705676 +100503060 Gm19531 MGI:MGI:5011716 +100503061 Gm19532 MGI:MGI:5011717 +100503066 Gm14966 MGI:MGI:3705223 +100503068 Gm11549 MGI:MGI:3650339|Ensembl:ENSMUSG00000085007 +100503069 Gm19535 MGI:MGI:5011720 +100503070 Gm11318 MGI:MGI:3651015 +100503071 Gm19536 MGI:MGI:5011721 +100503072 Gm16291 MGI:MGI:3826548|Ensembl:ENSMUSG00000087695 +100503073 Gm19537 MGI:MGI:5011722 +100503074 2610016A17Rik MGI:MGI:1919653|Ensembl:ENSMUSG00000101089 +100503077 Gm19540 MGI:MGI:5011725 +100503078 Gm19541 MGI:MGI:5011726 +100503082 2010110K18Rik MGI:MGI:1922951 +100503083 Gm19544 MGI:MGI:5011729 +100503085 Klhl3 MGI:MGI:2445185|Ensembl:ENSMUSG00000014164|Vega:OTTMUSG00000034604 +100503091 Gm19549 MGI:MGI:5011734 +100503093 Gm11334 MGI:MGI:3649250 +100503094 Gm19551 MGI:MGI:5011736 +100503095 Gm19552 MGI:MGI:5011737 +100503096 Gm19553 MGI:MGI:5011738 +100503099 Gm19554 MGI:MGI:5011739 +100503101 Gm17388 MGI:MGI:4937022 +100503104 Gm19557 MGI:MGI:5011742|Ensembl:ENSMUSG00000097990 +100503105 Gm13325 MGI:MGI:3650421 +100503106 Gm13944 MGI:MGI:3650359|Ensembl:ENSMUSG00000085845 +100503109 Gm16059 MGI:MGI:3802029 +100503111 Gm19560 MGI:MGI:5011745 +100503117 2010010A06Rik MGI:MGI:1913686|Ensembl:ENSMUSG00000102047 +100503118 Gm19563 MGI:MGI:5011748 +100503120 A930006K02Rik MGI:MGI:1925683|Ensembl:ENSMUSG00000084866 +100503122 Gm19565 MGI:MGI:5011750 +100503124 Gm14861 MGI:MGI:3802070 +100503125 Gm10913 MGI:MGI:3779121 +100503127 Gm19566 MGI:MGI:5011751 +100503130 Gm15964 MGI:MGI:3802003 +100503134 Gm19569 MGI:MGI:5011754 +100503138 Gm19571 MGI:MGI:5011756 +100503142 LOC100503142 - +100503143 Gm19572 MGI:MGI:5011757 +100503147 Gm13293 MGI:MGI:3649469|Ensembl:ENSMUSG00000086006 +100503152 Gm19578 MGI:MGI:5011763 +100503154 Gm19579 MGI:MGI:5011764 +100503157 Gm15471 MGI:MGI:3705197|Ensembl:ENSMUSG00000084997 +100503166 1700048M11Rik MGI:MGI:1920636|Ensembl:ENSMUSG00000085637 +100503167 Gm13752 MGI:MGI:3650596 +100503170 Gm15472 MGI:MGI:3707328 +100503175 Gm19582 MGI:MGI:5011767|Ensembl:ENSMUSG00000101942 +100503178 2810013P06Rik MGI:MGI:1914456|Ensembl:ENSMUSG00000099881 +100503184 Gm19583 MGI:MGI:5011768|Ensembl:ENSMUSG00000107192 +100503185 Btbd8 MGI:MGI:3646208|Ensembl:ENSMUSG00000111375 +100503190 Gm19585 MGI:MGI:5011770 +100503192 Gm19587 MGI:MGI:5011772 +100503197 Gm19589 MGI:MGI:5011774|Ensembl:ENSMUSG00000100798 +100503198 Gm19590 MGI:MGI:5011775 +100503199 5430416N02Rik MGI:MGI:1918676|Ensembl:ENSMUSG00000097772 +100503200 Gm17249 MGI:MGI:4936883 +100503203 Gm19592 MGI:MGI:5011777 +100503205 Gm15067 MGI:MGI:3705530 +100503209 A530041M06Rik MGI:MGI:3026943 +100503211 Rps12-ps9 MGI:MGI:3704324 +100503212 LOC100503212 - +100503219 Gm19596 MGI:MGI:5011781 +100503224 Gm14878 MGI:MGI:3708100 +100503225 Gm19598 MGI:MGI:5011783 +100503228 Gm12588 MGI:MGI:3800295 +100503229 Gm19599 MGI:MGI:5011784 +100503230 Gm19600 MGI:MGI:5011785 +100503231 Gm19601 MGI:MGI:5011786 +100503232 Gm11207 MGI:MGI:3650833 +100503237 Gm19605 MGI:MGI:5011790 +100503239 Gm14882 MGI:MGI:3705343 +100503240 Trpc5os MGI:MGI:3641805|Ensembl:ENSMUSG00000072934|Vega:OTTMUSG00000018931 +100503241 Gm13755 MGI:MGI:3651210 +100503242 Scgb2b6 MGI:MGI:5011792 +100503248 Gm15179 MGI:MGI:3705125|Ensembl:ENSMUSG00000085653 +100503250 Gm19610 MGI:MGI:5011795 +100503251 Gm19611 MGI:MGI:5011796 +100503252 Gm19612 MGI:MGI:5011797 +100503260 Gm19617 MGI:MGI:5011802 +100503265 Gm19619 MGI:MGI:5011804|Ensembl:ENSMUSG00000107198 +100503266 Gm19620 MGI:MGI:5011805 +100503268 Gm19622 MGI:MGI:5011807 +100503271 Gm19624 MGI:MGI:5011809 +100503272 Gm11423 MGI:MGI:3651335|Ensembl:ENSMUSG00000085175 +100503280 Gm38425 MGI:MGI:5621310 +100503288 Gm13778 MGI:MGI:3649233 +100503289 Gm14133 MGI:MGI:3651594|Ensembl:ENSMUSG00000087029 +100503292 Gm12279 MGI:MGI:3649630 +100503295 LOC100503295 - +100503302 Rps19-ps6 MGI:MGI:5011818 +100503307 Gm15408 MGI:MGI:3705101|Ensembl:ENSMUSG00000086610 +100503310 LOC100503310 - +100503311 Pifo MGI:MGI:1923670|Ensembl:ENSMUSG00000010136|Vega:OTTMUSG00000052519 +100503314 Gm15896 MGI:MGI:3801743 +100503318 Gm15853 MGI:MGI:3801970 +100503319 Gm17281 MGI:MGI:4936915 +100503323 A230087F16Rik MGI:MGI:2444635 +100503325 Gm19635 MGI:MGI:5011820 +100503327 Gm19637 MGI:MGI:5011822 +100503328 Gm19638 MGI:MGI:5011823 +100503330 AI464196 MGI:MGI:2139734 +100503331 Gm6724 MGI:MGI:3648052 +100503332 Gm19639 MGI:MGI:5011824 +100503333 Gm14007 MGI:MGI:3652193 +100503334 Gm15728 MGI:MGI:3783171 +100503335 Gm19640 MGI:MGI:5011825 +100503336 Gm19641 MGI:MGI:5011826 +100503337 Gm9895 MGI:MGI:3642802 +100503338 LOC100503338 - +100503339 Gm19642 MGI:MGI:5011827 +100503343 Gm19644 MGI:MGI:5011829 +100503344 Gm19645 MGI:MGI:5011830 +100503347 Gm19648 MGI:MGI:5011833 +100503348 Gm19649 MGI:MGI:5011834 +100503353 Gm14440 MGI:MGI:3702430|Ensembl:ENSMUSG00000078901|Vega:OTTMUSG00000016618 +100503355 Zfp648 MGI:MGI:2685049|Ensembl:ENSMUSG00000066797|Vega:OTTMUSG00000049816 +100503356 Gm19653 MGI:MGI:5011838 +100503357 AW060742 MGI:MGI:2142200 +100503358 Gm19654 MGI:MGI:5011839 +100503359 Ppp1r18os MGI:MGI:1918627 +100503361 Tmem95 MGI:MGI:3779488|Ensembl:ENSMUSG00000094845 +100503362 Rps12-ps26 MGI:MGI:3713332 +100503364 Gm19656 MGI:MGI:5011841 +100503366 Gm19658 MGI:MGI:5011843 +100503368 Gm20599 MGI:MGI:5295705 +100503369 Gm17584 MGI:MGI:4937218 +100503370 Gm19660 MGI:MGI:5011845 +100503374 Gm17435 MGI:MGI:4937069 +100503376 Gm19663 MGI:MGI:5011848 +100503378 Gm15638 MGI:MGI:3783082|Ensembl:ENSMUSG00000085826 +100503379 Gm16279 MGI:MGI:3826576 +100503380 Snhg4 MGI:MGI:4937091|Ensembl:ENSMUSG00000097769 +100503381 Gm14022 MGI:MGI:3649977 +100503382 Gm14530 MGI:MGI:3705621 +100503384 Gm19665 MGI:MGI:5011850 +100503385 Gm19666 MGI:MGI:5011851 +100503386 Tpbgl MGI:MGI:3646425|Ensembl:ENSMUSG00000096606|Vega:OTTMUSG00000043546 +100503387 Gm19667 MGI:MGI:5011852 +100503388 Gm19668 MGI:MGI:5011853|Ensembl:ENSMUSG00000096380|Vega:OTTMUSG00000049690 +100503390 Gm17518 MGI:MGI:4937152 +100503392 4833438C02Rik MGI:MGI:2147599 +100503393 Gm14827 MGI:MGI:3705192|Ensembl:ENSMUSG00000084904 +100503394 Gm17494 MGI:MGI:4937128 +100503395 Gm12313 MGI:MGI:3649993 +100503397 Gm11714 MGI:MGI:3649214 +100503399 Gm19673 MGI:MGI:5011858 +100503400 Ckb-ps1 MGI:MGI:5645789 +100503403 Gm13147 MGI:MGI:3651740 +100503410 Gm14795 MGI:MGI:3705480 +100503412 Gm6565 MGI:MGI:3644755 +100503414 Gm11650 MGI:MGI:3650132 +100503415 Gm19680 MGI:MGI:5011865 +100503419 Gm19683 MGI:MGI:5011868 +100503422 Gm19684 MGI:MGI:5011869 +100503425 Gm17469 MGI:MGI:4937103 +100503427 Gm10390 MGI:MGI:3708725|Ensembl:ENSMUSG00000097368 +100503428 C030017K20Rik MGI:MGI:2686516 +100503430 Cep112os1 MGI:MGI:3652256 +100503432 Gm19688 MGI:MGI:5011873 +100503433 Gm15433 MGI:MGI:3705860 +100503434 Gm19689 MGI:MGI:5011874 +100503435 AW124847 MGI:MGI:2147711 +100503437 Gm19691 MGI:MGI:5011876 +100503438 Gm19692 MGI:MGI:5011877 +100503443 Gm19694 MGI:MGI:5011879 +100503447 Gm19696 MGI:MGI:5011881 +100503450 Gm13720 MGI:MGI:3651372 +100503454 Gm16221 MGI:MGI:3802147 +100503455 Gm19702 MGI:MGI:5011887 +100503457 Gm19703 MGI:MGI:5011888 +100503459 Gm14539 MGI:MGI:3705371 +100503460 Gm19705 MGI:MGI:5011890|Ensembl:ENSMUSG00000097113 +100503461 Gm19706 MGI:MGI:5011891 +100503463 AI256396 MGI:MGI:1889797 +100503466 Gm19709 MGI:MGI:5011894 +100503467 AA667203 MGI:MGI:3034560 +100503468 Gm14023 MGI:MGI:3650639|Ensembl:ENSMUSG00000085498 +100503469 Gm19710 MGI:MGI:5011895|Ensembl:ENSMUSG00000105552 +100503470 Gm16619 MGI:MGI:4439543 +100503471 Gm15867 MGI:MGI:3801862 +100503473 Gm15074 MGI:MGI:3705470 +100503474 Platr22 MGI:MGI:4439804 +100503479 Gm19716 MGI:MGI:5011901 +100503481 4930453H23Rik MGI:MGI:1921933 +100503482 Gm649 MGI:MGI:2685495 +100503484 Gm19719 MGI:MGI:5011904 +100503486 Olfr936 MGI:MGI:3030770|Ensembl:ENSMUSG00000095194|Vega:OTTMUSG00000062257 +100503487 Gm19721 MGI:MGI:5011906 +100503490 Gm19723 MGI:MGI:5011908 +100503491 Gm19724 MGI:MGI:5011909 +100503493 Gm19726 MGI:MGI:5011911 +100503495 A930016O22Rik MGI:MGI:3605623|Ensembl:ENSMUSG00000040705 +100503496 Gm45916 MGI:MGI:5825553 +100503498 Gm16675 MGI:MGI:4439599|Ensembl:ENSMUSG00000097534 +100503499 Gm16136 MGI:MGI:3802137 +100503502 Gm10552 MGI:MGI:3642083 +100503506 Gm19733 MGI:MGI:5011918 +100503508 Gm13736 MGI:MGI:3650137 +100503513 Gm19739 MGI:MGI:5011924 +100503515 Gm19741 MGI:MGI:5011926 +100503518 Gm11827 MGI:MGI:3649801|Ensembl:ENSMUSG00000086765 +100503519 Gm19744 MGI:MGI:5011929 +100503524 Gm13567 MGI:MGI:3649435 +100503530 Gm11351 MGI:MGI:3649797|Ensembl:ENSMUSG00000086531 +100503533 Gm19755 MGI:MGI:5011940 +100503535 Gm11492 - +100503536 Gm19757 MGI:MGI:5011942|Ensembl:ENSMUSG00000108237 +100503538 Gm15941 MGI:MGI:3802081|Ensembl:ENSMUSG00000086992 +100503540 Gm19760 MGI:MGI:5011945 +100503542 Gm19761 MGI:MGI:5011946 +100503545 Nuggc MGI:MGI:2685446|Ensembl:ENSMUSG00000061356|Vega:OTTMUSG00000032810 +100503546 Gm15958 MGI:MGI:3801839 +100503547 Gm13650 MGI:MGI:3649525 +100503548 Gm19763 MGI:MGI:5011948 +100503549 Gm10354 MGI:MGI:3809109|Ensembl:ENSMUSG00000072188|Vega:OTTMUSG00000036596 +100503550 Gm19764 MGI:MGI:5011949 +100503551 Lrrc8dos MGI:MGI:3802116 +100503552 Gm19765 MGI:MGI:5011950 +100503553 Gm20603 MGI:MGI:5298204 +100503563 Gm10240 MGI:MGI:3704454 +100503564 Gm19771 MGI:MGI:5011956 +100503565 Gm9926 MGI:MGI:3642582 +100503567 Gm11694 MGI:MGI:3650243 +100503568 Gm10602 MGI:MGI:3708759 +100503569 Gm16754 MGI:MGI:4439678 +100503571 Gm19774 MGI:MGI:5011959 +100503572 Bbip1 MGI:MGI:1913610|Ensembl:ENSMUSG00000084957 +100503573 Gm19775 MGI:MGI:5011960 +100503575 Gm19777 MGI:MGI:5011962 +100503580 Gm19782 MGI:MGI:5011967 +100503582 Gm19784 MGI:MGI:5011969 +100503583 Fsbp MGI:MGI:5301008|Ensembl:ENSMUSG00000094595|Vega:OTTMUSG00000042338 +100503584 Zfp534 MGI:MGI:3650650|Ensembl:ENSMUSG00000062518|Vega:OTTMUSG00000010681 +100503585 Gm10059 MGI:MGI:3642158 +100503586 Gm11702 MGI:MGI:3649846 +100503588 Gm19785 MGI:MGI:5011970 +100503590 Gm19786 MGI:MGI:5011971 +100503592 A330076C08Rik MGI:MGI:2443693|Ensembl:ENSMUSG00000113186 +100503594 LOC100503594 - +100503595 Gm13003 MGI:MGI:3650099|Ensembl:ENSMUSG00000085833 +100503598 Gm19790 MGI:MGI:5011975 +100503599 Gm19791 MGI:MGI:5011976 +100503600 Gm19792 MGI:MGI:5011977 +100503605 Hbb-bs MGI:MGI:5474852|Ensembl:ENSMUSG00000052305|Vega:OTTMUSG00000023334 +100503607 BB319198 MGI:MGI:3035369 +100503608 Gm17366 MGI:MGI:4937000 +100503609 Lnp1 MGI:MGI:5011982|Ensembl:ENSMUSG00000109588|Vega:OTTMUSG00000060400 +100503612 Gm19798 MGI:MGI:5011983 +100503613 5031434C07Rik MGI:MGI:2442810 +100503619 E330011O21Rik MGI:MGI:3759668|Ensembl:ENSMUSG00000109841 +100503620 Gm15337 MGI:MGI:3705103 +100503621 Gm14865 MGI:MGI:3705664 +100503622 Gm16630 MGI:MGI:4439554|Ensembl:ENSMUSG00000107875 +100503624 Gm19801 MGI:MGI:5011986 +100503625 Gm19802 MGI:MGI:5011987 +100503629 Gm11704 MGI:MGI:3649839 +100503630 Gm12002 MGI:MGI:3651521 +100503631 Gm19805 MGI:MGI:5011990 +100503632 Gm16892 MGI:MGI:4439816 +100503634 Gm19807 MGI:MGI:5011992 +100503636 1700123M08Rik MGI:MGI:1923915 +100503642 Gm19810 MGI:MGI:5011995 +100503643 Gm19811 MGI:MGI:5011996 +100503648 Gm19815 MGI:MGI:5012000 +100503650 Sap30bpos MGI:MGI:3650575 +100503651 Gm15354 MGI:MGI:3705093 +100503652 Gm16845 MGI:MGI:4439769|Ensembl:ENSMUSG00000096981 +100503653 Gm14036 MGI:MGI:3649581 +100503654 Gm19816 MGI:MGI:5012001 +100503655 Gm19817 MGI:MGI:5012002 +100503659 Cbarp MGI:MGI:1354170|Ensembl:ENSMUSG00000035640|Vega:OTTMUSG00000000007 +100503661 1700010B13Rik MGI:MGI:1922741 +100503664 Gm13012 MGI:MGI:3652270 +100503669 Gm6134 MGI:MGI:3648731 +100503670 Rpl5 MGI:MGI:102854|Ensembl:ENSMUSG00000058558|Vega:OTTMUSG00000028907 +100503674 Gm19825 MGI:MGI:5012010 +100503675 Gm13252 MGI:MGI:3651953 +100503676 Gm38426 MGI:MGI:5621311|Ensembl:ENSMUSG00000003812 +100503680 Rapgef4os2 MGI:MGI:2139429 +100503682 Gm19829 MGI:MGI:5012014 +100503684 Gm15125 MGI:MGI:3705848 +100503685 Gm15567 MGI:MGI:3783016 +100503690 Gm19835 MGI:MGI:5012020 +100503691 Gm14552 MGI:MGI:3801915 +100503694 Gm19838 MGI:MGI:5012023 +100503696 LOC100503696 - +100503698 Gm19840 MGI:MGI:5012025 +100503701 Gm19843 MGI:MGI:5012028 +100503703 Gm19845 MGI:MGI:5012030 +100503704 Gm16861 MGI:MGI:4439785|Ensembl:ENSMUSG00000097397 +100503706 Gm19847 MGI:MGI:5012032 +100503708 Gm19849 MGI:MGI:5012034 +100503709 Gm15126 MGI:MGI:3705804 +100503710 Gm5741 MGI:MGI:3645690|Ensembl:ENSMUSG00000095845 +100503713 Gm16141 MGI:MGI:3802122 +100503715 Gm19853 MGI:MGI:5012038 +100503716 Gm19854 MGI:MGI:5012039 +100503717 Gm19855 MGI:MGI:5012040 +100503719 Gm13437 MGI:MGI:3652333 +100503724 Dnajc19-ps MGI:MGI:3709029 +100503725 Gm17508 MGI:MGI:4937142 +100503727 1700011B04Rik MGI:MGI:1922894|Ensembl:ENSMUSG00000102099 +100503729 Gm19859 MGI:MGI:5012044 +100503730 Gm19860 MGI:MGI:5012045 +100503733 LOC100503733 Ensembl:ENSMUSG00000094741 +100503734 Gm19863 MGI:MGI:5012048 +100503735 Gm7177 MGI:MGI:3647987 +100503737 Gm11857 MGI:MGI:3649311 +100503743 Gm19866 MGI:MGI:5012051 +100503744 Gm19867 MGI:MGI:5012052 +100503749 Gm15084 MGI:MGI:3705882 +100503751 Gm19872 MGI:MGI:5012057|Ensembl:ENSMUSG00000098295 +100503752 Gm12224 MGI:MGI:3651369 +100503753 Gm19873 MGI:MGI:5012058 +100503754 Gm11725 MGI:MGI:3649385|Ensembl:ENSMUSG00000085434 +100503758 Gm19876 MGI:MGI:5012061 +100503759 Gm5084 MGI:MGI:3647835 +100503763 Gm19880 MGI:MGI:5012065 +100503766 Gm19883 MGI:MGI:5012068 +100503767 Gm17473 MGI:MGI:4937107 +100503769 Gm13506 MGI:MGI:3649429 +100503770 Gm19885 MGI:MGI:5012070 +100503771 Gm14541 MGI:MGI:3709642 +100503780 Gm15094 MGI:MGI:3705884 +100503781 Gm19891 MGI:MGI:5012076 +100503783 Gm17733 MGI:MGI:4937367|Ensembl:ENSMUSG00000097486 +100503784 Gm19893 MGI:MGI:5012078 +100503785 Igf1it MGI:MGI:5012079 +100503786 LOC100503786 - +100503789 Gm19896 MGI:MGI:5012081 +100503790 Gm19897 MGI:MGI:5012082 +100503791 Gm16201 MGI:MGI:3802153 +100503792 Gm19898 MGI:MGI:5012083 +100503793 LOC100503793 - +100503794 Gm9920 MGI:MGI:3642228|Ensembl:ENSMUSG00000053749|Vega:OTTMUSG00000024432 +100503795 Gm19899 MGI:MGI:5012084 +100503796 Gm19900 MGI:MGI:5012085 +100503797 Gm11738 MGI:MGI:3650365 +100503798 Gm19901 MGI:MGI:5012086 +100503799 Gm7931 MGI:MGI:3643448 +100503802 Gm10419 MGI:MGI:3642823 +100503803 Gm17434 MGI:MGI:4937068 +100503805 Gm19905 MGI:MGI:5012090 +100503808 Gm14925 MGI:MGI:3801742 +100503810 Gm13056 MGI:MGI:3650725|Ensembl:ENSMUSG00000085395 +100503811 Gm19908 MGI:MGI:5012093 +100503812 3300002A11Rik MGI:MGI:1919073 +100503815 Rpl39-ps MGI:MGI:3705781 +100503816 Gm16548 MGI:MGI:4414968|Ensembl:ENSMUSG00000086593 +100503818 Gm19911 MGI:MGI:5012096 +100503819 Gm12454 MGI:MGI:3649695 +100503822 LOC100503822 - +100503823 Gm16973 MGI:MGI:4439897 +100503826 Gm13075 MGI:MGI:3651958 +100503827 Tnfsf13os MGI:MGI:1919587 +100503830 Gm11762 MGI:MGI:3651277|Ensembl:ENSMUSG00000087675 +100503831 Gm38427 MGI:MGI:5621312 +100503834 Gm19916 MGI:MGI:5012101 +100503835 Gm19917 MGI:MGI:5012102 +100503836 Gm19918 MGI:MGI:5012103 +100503839 Gm12481 MGI:MGI:3650743 +100503840 Gm19920 MGI:MGI:5012105 +100503841 Gm19921 MGI:MGI:5012106 +100503842 2410022M11Rik MGI:MGI:1917005 +100503846 Gm19924 MGI:MGI:5012109 +100503849 Sp3os MGI:MGI:1914936 +100503851 Gm14674 MGI:MGI:3705677 +100503852 Gm19927 MGI:MGI:5012112 +100503854 Rps23-ps2 MGI:MGI:3642236 +100503855 Gm19929 MGI:MGI:5012114 +100503856 1700024B05Rik MGI:MGI:1922768|Ensembl:ENSMUSG00000052334|Vega:OTTMUSG00000036336 +100503857 Gm13489 MGI:MGI:3651216 +100503859 1110015O18Rik MGI:MGI:1915766|Ensembl:ENSMUSG00000098659 +100503861 Gm19931 MGI:MGI:5012116 +100503862 Gm19932 MGI:MGI:5012117 +100503866 Gm15558 MGI:MGI:3783007 +100503867 Rps10-ps3 MGI:MGI:3649547 +100503868 Gm19935 MGI:MGI:5012120|Ensembl:ENSMUSG00000110332|Vega:OTTMUSG00000060323 +100503869 Mkln1os MGI:MGI:3651306|Ensembl:ENSMUSG00000086212 +100503870 Gm19936 MGI:MGI:5012121 +100503871 4833432E10Rik MGI:MGI:1926032 +100503872 Hotair MGI:MGI:3826586|Ensembl:ENSMUSG00000086903 +100503873 Gm19937 MGI:MGI:5012122 +100503874 Gm19938 MGI:MGI:5012123 +100503875 Vmn2r-ps120 MGI:MGI:3761538 +100503876 Gm19939 MGI:MGI:5012124 +100503878 Zfp683 MGI:MGI:3650254 +100503879 Gm5901 MGI:MGI:3643909|Ensembl:ENSMUSG00000078611|Vega:OTTMUSG00000060486 +100503881 Gm10343 MGI:MGI:3642690 +100503882 Gm17308 MGI:MGI:4936942|Ensembl:ENSMUSG00000096922 +100503884 Ccdc149 MGI:MGI:2685293|Ensembl:ENSMUSG00000045790|Vega:OTTMUSG00000054571 +100503886 Gm19943 MGI:MGI:5012128 +100503887 Gm17067 MGI:MGI:4937894 +100503890 Pet100 MGI:MGI:3615306|Ensembl:ENSMUSG00000087687|Vega:OTTMUSG00000059168 +100503892 AI746446 MGI:MGI:2145284 +100503893 Gm19945 MGI:MGI:5012130 +100503895 Tpsab1 MGI:MGI:96943|Ensembl:ENSMUSG00000024173|Vega:OTTMUSG00000033716 +100503900 Gm19949 MGI:MGI:5012134 +100503901 Gm19950 MGI:MGI:5012135 +100503902 Gm19951 MGI:MGI:5012136 +100503907 Gm19955 MGI:MGI:5012140 +100503908 Gm19956 MGI:MGI:5012141 +100503912 Gm11772 MGI:MGI:3649468 +100503914 Gm19961 MGI:MGI:5012146 +100503915 Smpd5 MGI:MGI:3709877|Ensembl:ENSMUSG00000071724|Vega:OTTMUSG00000035742 +100503918 Gm19963 MGI:MGI:5012148 +100503920 Gm19965 MGI:MGI:5012150 +100503921 Gm19966 MGI:MGI:5012151 +100503922 Gm19967 MGI:MGI:5012152 +100503923 LOC100503923 - +100503924 Fcor MGI:MGI:1915484|Ensembl:ENSMUSG00000089665|Vega:OTTMUSG00000035068 +100503925 Gm17540 MGI:MGI:4937174 +100503927 Gm19969 MGI:MGI:5012154 +100503931 Gm19972 MGI:MGI:5012157 +100503935 Gm15101 MGI:MGI:3782931 +100503938 Gm19976 MGI:MGI:5012161 +100503944 Gm19980 MGI:MGI:5012165 +100503946 LOC100503946 - +100503949 Zfp965 MGI:MGI:3779822|Ensembl:ENSMUSG00000078896|Vega:OTTMUSG00000034086 +100503951 Gm19985 MGI:MGI:5012170 +100503952 Gm13433 MGI:MGI:3651454 +100503954 Gm12462 MGI:MGI:3650646 +100503956 LOC100503956 - +100503958 Gm19987 MGI:MGI:5012172 +100503960 Gm19989 MGI:MGI:5012174 +100503961 Gm19990 MGI:MGI:5012175|Ensembl:ENSMUSG00000112164 +100503962 Gm16701 MGI:MGI:4439625|Ensembl:ENSMUSG00000102548 +100503964 Gm17266 MGI:MGI:4936900 +100503965 Gm12167 MGI:MGI:3650837 +100503967 Cyp2b26-ps MGI:MGI:3648075 +100503969 1810008I18Rik MGI:MGI:1920875 +100503970 AY761185 MGI:MGI:3630303|Ensembl:ENSMUSG00000079120|Vega:OTTMUSG00000018344 +100503971 Gm3468 MGI:MGI:3781644 +100503973 LOC100503973 - +100503976 Gm19994 MGI:MGI:5012179 +100503980 Gm11483 MGI:MGI:3652237 +100503981 Gm15484 MGI:MGI:3705726 +100503982 Gm19998 MGI:MGI:5012183 +100503986 Gm17227 MGI:MGI:4938054 +100503991 Acpt MGI:MGI:3644563|Ensembl:ENSMUSG00000012777|Vega:OTTMUSG00000023113 +100503992 Gm6040 MGI:MGI:3646527|Ensembl:ENSMUSG00000071165|Vega:OTTMUSG00000018889 +100503994 Gm20003 MGI:MGI:5012188 +100503997 Gm20550 MGI:MGI:5294601 +100503999 Gm20005 MGI:MGI:5012190 +100504000 Gm20006 MGI:MGI:5012191 +100504001 Gm20007 MGI:MGI:5012192 +100504002 Gm20008 MGI:MGI:5012193 +100504003 Gm14839 MGI:MGI:3801784 +100504007 Gm15787 MGI:MGI:3783229|Ensembl:ENSMUSG00000086247 +100504013 Gm20014 MGI:MGI:5012199 +100504014 Gm15056 MGI:MGI:3705859|Ensembl:ENSMUSG00000082976|Vega:OTTMUSG00000018888 +100504018 Gm20016 MGI:MGI:5012201 +100504019 C1qtnf9bos MGI:MGI:5012202 +100504021 Gm17638 MGI:MGI:4937272 +100504022 Gm20018 MGI:MGI:5012203 +100504023 Gm13553 MGI:MGI:3650620 +100504026 Gm16157 MGI:MGI:3801721|Ensembl:ENSMUSG00000086628 +100504029 Gm16740 MGI:MGI:4439664|Ensembl:ENSMUSG00000097167 +100504031 Gm20022 MGI:MGI:5012207 +100504036 Gm20026 MGI:MGI:5012211 +100504037 Gm16021 MGI:MGI:3802111 +100504039 LOC100504039 - +100504040 Gm17586 MGI:MGI:4937220 +100504043 Gm17529 MGI:MGI:4937163 +100504047 Gm20032 MGI:MGI:5012217 +100504048 Gm20033 MGI:MGI:5012218 +100504049 Gm15559 MGI:MGI:3783008|Ensembl:ENSMUSG00000086401 +100504052 Gm2962 MGI:MGI:3781140 +100504053 Gm13788 MGI:MGI:3650569 +100504056 Gm20036 MGI:MGI:5012221 +100504058 Gm20038 MGI:MGI:5012223 +100504059 Gm20039 MGI:MGI:5012224 +100504061 8030451A03Rik MGI:MGI:1915353 +100504063 Gm20978 MGI:MGI:5434333 +100504064 Gm20040 MGI:MGI:5012225 +100504066 LOC100504066 - +100504069 Gm15915 MGI:MGI:3801763|Ensembl:ENSMUSG00000085723 +100504070 Gm20043 MGI:MGI:5012228|Ensembl:ENSMUSG00000113410 +100504071 Gm20044 MGI:MGI:5012229 +100504072 Gm20045 MGI:MGI:5012230 +100504073 Gm13804 MGI:MGI:3651562 +100504078 Gm20049 MGI:MGI:5012234 +100504082 Gm15147 MGI:MGI:3705862 +100504083 Gm20052 MGI:MGI:5012237 +100504087 Gm14593 MGI:MGI:3705445 +100504088 Gm11338 MGI:MGI:3651857 +100504089 Gm20056 MGI:MGI:5012241 +100504091 Gm20058 MGI:MGI:5012243 +100504097 Gm13813 MGI:MGI:3649511 +100504101 Gm20063 MGI:MGI:5012248|Ensembl:ENSMUSG00000113429 +100504102 Gm20064 MGI:MGI:5012249 +100504103 Gm13186 MGI:MGI:3649441 +100504104 Gm16062 MGI:MGI:3802162|Ensembl:ENSMUSG00000087249 +100504107 Gm20067 MGI:MGI:5012252 +100504109 Gm11336 MGI:MGI:3651860 +100504111 Gm11882 MGI:MGI:3651786 +100504112 Ccer2 MGI:MGI:3645242|Ensembl:ENSMUSG00000096257|Vega:OTTMUSG00000059068 +100504113 Gm20069 MGI:MGI:5012254 +100504114 Gm16907 MGI:MGI:4439831|Ensembl:ENSMUSG00000097242 +100504115 Gm20070 MGI:MGI:5012255 +100504116 Gm20071 MGI:MGI:5012256 +100504117 Chrna1os MGI:MGI:3651120 +100504118 Gm20072 MGI:MGI:5012257 +100504121 Med9os MGI:MGI:1916628|Ensembl:ENSMUSG00000085260 +100504123 Gm20074 MGI:MGI:5012259 +100504124 Gm11936 MGI:MGI:3650814 +100504125 Gm20075 MGI:MGI:5012260 +100504127 Gm17690 MGI:MGI:4937324 +100504130 Gm17655 MGI:MGI:4937289 +100504133 Gm20079 MGI:MGI:5012264 +100504135 Gm20081 MGI:MGI:5012266 +100504136 Gm20082 MGI:MGI:5012267 +100504138 Gm14163 MGI:MGI:3651972 +100504139 Gm16685 MGI:MGI:4439609 +100504140 4930412M03Rik MGI:MGI:2443570 +100504141 Gm20083 MGI:MGI:5012268 +100504144 Gm13421 MGI:MGI:3649922 +100504145 Platr30 MGI:MGI:4937214|Ensembl:ENSMUSG00000097851 +100504146 Gm14390 MGI:MGI:3649570 +100504149 Gm11514 MGI:MGI:3649789 +100504153 Gm20089 MGI:MGI:5012274 +100504154 Gm15050 MGI:MGI:3705180|Ensembl:ENSMUSG00000087626 +100504156 Fam181a MGI:MGI:3647570|Ensembl:ENSMUSG00000096753|Vega:OTTMUSG00000047115 +100504157 Gm20091 MGI:MGI:5012276 +100504159 Gm20093 MGI:MGI:5012278 +100504160 Gm20094 MGI:MGI:5012279 +100504162 Prss51 MGI:MGI:1921465|Ensembl:ENSMUSG00000052099|Vega:OTTMUSG00000036313 +100504163 Gm20096 MGI:MGI:5012281 +100504164 Cmtm1 MGI:MGI:2447159|Ensembl:ENSMUSG00000110430|Vega:OTTMUSG00000035025 +100504166 4933421O10Rik MGI:MGI:1918323|Ensembl:ENSMUSG00000085037 +100504169 Gm20098 MGI:MGI:5012283 +100504170 Gm20099 MGI:MGI:5012284 +100504171 Gm17575 MGI:MGI:4937209 +100504172 Gm15171 MGI:MGI:3705505 +100504173 Gm15466 MGI:MGI:3705491 +100504174 Gm15682 MGI:MGI:3783124 +100504175 Gm20100 MGI:MGI:5012285 +100504176 Gm20101 MGI:MGI:5012286 +100504177 F730016J06Rik MGI:MGI:2443559 +100504178 Dhrs13os MGI:MGI:1924478|Ensembl:ENSMUSG00000087050 +100504179 Gm11930 MGI:MGI:3650032 +100504180 LOC100504180 Ensembl:ENSMUSG00000058537|Vega:OTTMUSG00000037621 +100504181 Gm20102 MGI:MGI:5012287 +100504183 Krtap16-1 MGI:MGI:3650326|Ensembl:ENSMUSG00000078253|Vega:OTTMUSG00000002209 +100504184 Gm16336 MGI:MGI:3840146|Ensembl:ENSMUSG00000087160 +100504186 C230013L11Rik MGI:MGI:2442581 +100504187 Gm13392 MGI:MGI:3649898 +100504189 Gm20104 MGI:MGI:5012289 +100504191 Gm16576 MGI:MGI:4414996|Ensembl:ENSMUSG00000087543 +100504194 Gm11922 MGI:MGI:3650177 +100504195 Micalcl MGI:MGI:1918127|Ensembl:ENSMUSG00000030771|Vega:OTTMUSG00000024789 +100504196 Gm10023 MGI:MGI:3704333 +100504197 Gm13771 MGI:MGI:3650181 +100504199 Gm20108 MGI:MGI:5012293 +100504200 Gm8050 MGI:MGI:3779779|Ensembl:ENSMUSG00000091814|Vega:OTTMUSG00000036151 +100504201 Gm20109 MGI:MGI:5012294 +100504202 Gm20110 MGI:MGI:5012295|Ensembl:ENSMUSG00000111962 +100504203 Gm20111 MGI:MGI:5012296 +100504206 Gm16055 MGI:MGI:3801818 +100504207 Arhgap33os MGI:MGI:2685928|Ensembl:ENSMUSG00000062132 +100504209 Gm12351 MGI:MGI:3650346 +100504212 Gm13786 MGI:MGI:3649782 +100504213 Gm14421 MGI:MGI:3652254 +100504215 Gm20115 MGI:MGI:5012300 +100504220 Gm20118 MGI:MGI:5012303 +100504221 Efcab8 MGI:MGI:3644206|Ensembl:ENSMUSG00000044083|Vega:OTTMUSG00000016826 +100504224 Gm20121 MGI:MGI:5012306 +100504225 Gm9828 MGI:MGI:3642913 +100504229 A530017D24Rik MGI:MGI:2144320 +100504230 AU020206 MGI:MGI:2142134 +100504231 Gm15708 MGI:MGI:3783149|Ensembl:ENSMUSG00000086894 +100504232 Mptx2 MGI:MGI:3779286|Ensembl:ENSMUSG00000079180|Vega:OTTMUSG00000050170 +100504233 Gm20124 MGI:MGI:5012309 +100504234 Ccdc170 MGI:MGI:2685067|Ensembl:ENSMUSG00000019767|Vega:OTTMUSG00000032752 +100504235 Gm20125 MGI:MGI:5012310|Ensembl:ENSMUSG00000101969 +100504237 Gm20127 MGI:MGI:5012312 +100504238 Gm20128 MGI:MGI:5012313 +100504239 Gm10591 MGI:MGI:3711256|Ensembl:ENSMUSG00000096596 +100504241 Scgb1b34-ps MGI:MGI:5012314 +100504245 Gm29694 MGI:MGI:5588853 +100504247 Gm14416 MGI:MGI:3702407 +100504249 Gm15350 MGI:MGI:3705181|Ensembl:ENSMUSG00000084780 +100504250 Gm10088 MGI:MGI:3641695 +100504252 Gm14198 MGI:MGI:3652051 +100504254 Gm15903 MGI:MGI:3802037 +100504255 Gm12159 MGI:MGI:3649482|Ensembl:ENSMUSG00000084773 +100504258 Gm13425 MGI:MGI:3649915 +100504259 Gm20136 MGI:MGI:5012321 +100504261 Gm17608 MGI:MGI:4937242 +100504262 A730020E08Rik MGI:MGI:2444999 +100504263 2210418O10Rik MGI:MGI:1924208|Ensembl:ENSMUSG00000078894|Vega:OTTMUSG00000034101 +100504265 Gm20139 MGI:MGI:5012324 +100504266 Gm20140 MGI:MGI:5012325 +100504267 Trp53cor1 MGI:MGI:3801771|Ensembl:ENSMUSG00000085912 +100504268 2310005A03Rik MGI:MGI:1923981|Ensembl:ENSMUSG00000087254 +100504274 Gm20144 MGI:MGI:5012329 +100504277 Rpl31-ps13 MGI:MGI:3809036 +100504278 2810402E24Rik MGI:MGI:1913715 +100504280 Gm20147 MGI:MGI:5012332 +100504281 Gm14238 MGI:MGI:3651676 +100504283 Gm20149 MGI:MGI:5012334 +100504285 Abhd12b MGI:MGI:2685650|Ensembl:ENSMUSG00000090121|Vega:OTTMUSG00000034963 +100504286 Gm20150 MGI:MGI:5012335 +100504287 Ifi203-ps MGI:MGI:3840117 +100504291 Gm16618 MGI:MGI:4439542 +100504292 Gm20153 MGI:MGI:5012338 +100504296 Gm20156 MGI:MGI:5012341 +100504297 Gm20157 MGI:MGI:5012342 +100504299 Gm20159 MGI:MGI:5012344 +100504301 6230426M11Rik MGI:MGI:3648960 +100504304 Gm20161 MGI:MGI:5012346 +100504305 Gm16534 MGI:MGI:4413442 +100504306 Gm20162 MGI:MGI:5012347 +100504307 Gm20163 MGI:MGI:5012348 +100504308 Gm15473 MGI:MGI:3705105 +100504309 Toporsos MGI:MGI:1913684|Vega:OTTMUSG00000006580 +100504312 Gm17597 MGI:MGI:4937231|Ensembl:ENSMUSG00000097613 +100504313 Gm20164 MGI:MGI:5012349 +100504317 Gm20167 MGI:MGI:5012352 +100504319 Gm13611 MGI:MGI:3651300 +100504320 Gm20169 MGI:MGI:5012354 +100504323 Gm20172 MGI:MGI:5012357 +100504325 Gm11007 MGI:MGI:3779223 +100504328 Gm14406 MGI:MGI:3649838 +100504330 Gm20177 MGI:MGI:5012362 +100504331 Gm11679 MGI:MGI:3650353 +100504333 Gm16712 MGI:MGI:4439636|Ensembl:ENSMUSG00000097077 +100504335 Gm20179 MGI:MGI:5012364 +100504338 Gm12163 MGI:MGI:3650636 +100504342 Gm13413 MGI:MGI:3650613 +100504344 Gm20186 MGI:MGI:5012371 +100504346 Gm13304 MGI:MGI:3710514|Ensembl:ENSMUSG00000073878|Vega:OTTMUSG00000011350 +100504347 Gm20187 MGI:MGI:5012372|Ensembl:ENSMUSG00000094002 +100504349 Gm13187 MGI:MGI:3649588 +100504350 Gm14169 MGI:MGI:3651156|Ensembl:ENSMUSG00000086118 +100504351 Gm20188 MGI:MGI:5012373 +100504352 C78197 MGI:MGI:2144636 +100504354 Gm20982 MGI:MGI:5434337 +100504356 Gm20190 MGI:MGI:5012375 +100504357 Gm14974 MGI:MGI:3802032 +100504360 D730003I15Rik MGI:MGI:1925971 +100504361 Gm14230 MGI:MGI:3652157 +100504362 Gm1987 MGI:MGI:3780156|Ensembl:ENSMUSG00000095320 +100504371 Gm13920 MGI:MGI:3651615 +100504375 Gm15880 MGI:MGI:3802014|Ensembl:ENSMUSG00000084821 +100504377 Gm20199 MGI:MGI:5012384 +100504379 Gm20201 MGI:MGI:5012386 +100504380 Gm13321 MGI:MGI:3649673 +100504381 Gm17276 MGI:MGI:4936910 +100504382 Gm14551 MGI:MGI:3705667 +100504387 Gm13868 MGI:MGI:3651789 +100504388 Kat2b-ps MGI:MGI:3648817 +100504389 9030407P20Rik MGI:MGI:1918818 +100504390 Gm15366 MGI:MGI:3709611 +100504394 Gm20203 MGI:MGI:5012388 +100504395 Gm20204 MGI:MGI:5012389 +100504398 Gm20206 MGI:MGI:5012391 +100504399 C130021I20Rik MGI:MGI:3639863 +100504400 Cypt14 MGI:MGI:3616459|Ensembl:ENSMUSG00000095240 +100504402 Gm20208 MGI:MGI:5012393 +100504404 H2-Ea-ps MGI:MGI:95900 +100504405 Rpl30-ps10 MGI:MGI:3646270 +100504406 Gm10617 MGI:MGI:3708793 +100504409 Gm15358 MGI:MGI:3705720 +100504412 Kcnmb4os2 MGI:MGI:1918263|Ensembl:ENSMUSG00000085837 +100504420 Gm12874 MGI:MGI:3651901 +100504421 2900076A07Rik MGI:MGI:1920242|Ensembl:ENSMUSG00000097277 +100504425 Gm20219 MGI:MGI:5012404|Ensembl:ENSMUSG00000110218|Vega:OTTMUSG00000060183 +100504427 Gm13404 MGI:MGI:3649379 +100504429 Spin2d MGI:MGI:1922101|Ensembl:ENSMUSG00000079566|Vega:OTTMUSG00000017698 +100504431 Gm20223 MGI:MGI:5012408 +100504432 Gm12362 MGI:MGI:3652292 +100504440 Gm14577 MGI:MGI:3705762 +100504444 Gm21977 MGI:MGI:5439446 +100504446 Prr22 MGI:MGI:2685392|Ensembl:ENSMUSG00000090273|Vega:OTTMUSG00000048637 +100504448 Gm20234 MGI:MGI:5012419 +100504452 Gm20235 MGI:MGI:5012420 +100504453 Gm20236 MGI:MGI:5012421 +100504454 4930573C08Rik MGI:MGI:1923116 +100504455 Gm15834 MGI:MGI:3802168 +100504457 4921513H07Rik MGI:MGI:1918106 +100504458 Gm12367 MGI:MGI:3649554 +100504461 5430401H09Rik MGI:MGI:1918646 +100504462 1700007J24Rik MGI:MGI:1922742 +100504464 E230016K23Rik MGI:MGI:3041204|Ensembl:ENSMUSG00000051832 +100504465 Gm20239 MGI:MGI:5012424 +100504467 Gm16596 MGI:MGI:4439520 +100504468 Gm20241 MGI:MGI:5012426 +100504469 Gm20242 MGI:MGI:5012427 +100504470 Gm20243 MGI:MGI:5012428 +100504474 Smlr1 MGI:MGI:1922856|Ensembl:ENSMUSG00000096546|Vega:OTTMUSG00000049743 +100504477 Gm16677 MGI:MGI:4439601 +100504479 Gm13450 MGI:MGI:3650133 +100504482 Gm17184 MGI:MGI:4938011 +100504483 Cbx3-ps7 MGI:MGI:3704187 +100504484 Gm17695 MGI:MGI:4937329 +100504486 Gdap10 MGI:MGI:1338008 +100504488 Gm3164 MGI:MGI:3781343 +100504491 Dcdc2b MGI:MGI:2686212|Ensembl:ENSMUSG00000078552|Vega:OTTMUSG00000009523 +100504492 Gm20987 MGI:MGI:5434342 +100504493 Gm13605 MGI:MGI:3652204 +100504496 Gm20255 MGI:MGI:5012440 +100504497 Gm16233 MGI:MGI:3802088 +100504501 Gm20257 MGI:MGI:5012442|Ensembl:ENSMUSG00000102059 +100504502 Gm14633 MGI:MGI:3705509 +100504504 4833423F13Rik MGI:MGI:1921006 +100504506 Gm12891 MGI:MGI:3649646 +100504508 BC085271 MGI:MGI:3612444 +100504511 Gm29349 MGI:MGI:5580055 +100504512 4930426I24Rik MGI:MGI:1921125 +100504516 Gm20262 MGI:MGI:5012447 +100504517 Atxn7l1os1 MGI:MGI:3779275 +100504518 3425401B19Rik MGI:MGI:3588196|Ensembl:ENSMUSG00000071540 +100504520 Gm15400 MGI:MGI:3705651 +100504523 Gm20266 MGI:MGI:5012451 +100504524 Cisd3b MGI:MGI:5012452 +100504525 Gm20268 MGI:MGI:5012453|Ensembl:ENSMUSG00000100684 +100504527 Gm10374 MGI:MGI:3708554 +100504535 LOC100504535 - +100504537 Gm13302 MGI:MGI:3705777 +100504538 Gm20274 MGI:MGI:5012459 +100504539 Gm20275 MGI:MGI:5012460 +100504540 Gm20276 MGI:MGI:5012461 +100504542 Gm20277 MGI:MGI:5012462 +100504544 Gm13417 MGI:MGI:3652159 +100504547 Gm20281 MGI:MGI:5012466 +100504549 AI463170 MGI:MGI:2144839|Ensembl:ENSMUSG00000112388 +100504555 Gm12819 MGI:MGI:3652017 +100504556 D5Ertd683e MGI:MGI:1277132 +100504559 Gm20287 MGI:MGI:5012472 +100504561 9230112J17Rik MGI:MGI:1924999|Ensembl:ENSMUSG00000111761 +100504562 Gm20288 MGI:MGI:5012473 +100504563 Gm13992 MGI:MGI:3651472 +100504566 Gm20290 MGI:MGI:5012475 +100504568 Gm17634 MGI:MGI:4937268|Ensembl:ENSMUSG00000097482 +100504569 Gm13205 MGI:MGI:3700976 +100504573 Gm15464 MGI:MGI:3646025 +100504574 Gm20294 MGI:MGI:5012479 +100504581 Gm17275 MGI:MGI:4936909 +100504586 Gm20300 MGI:MGI:5012485|Ensembl:ENSMUSG00000111080 +100504589 Gm11454 MGI:MGI:3650530 +100504590 Gm20302 MGI:MGI:5012487 +100504591 Gm15987 MGI:MGI:3801849 +100504592 1700104B16Rik MGI:MGI:1925886 +100504593 Gm13431 MGI:MGI:3650776 +100504594 A630012P03Rik MGI:MGI:2442968|Ensembl:ENSMUSG00000055110 +100504597 Gm20304 MGI:MGI:5012489 +100504598 Gm20305 MGI:MGI:5012490 +100504601 Gm16702 MGI:MGI:4439626|Ensembl:ENSMUSG00000097796 +100504604 Gm16316 MGI:MGI:3826530 +100504605 Gm20310 MGI:MGI:5012495 +100504606 Gm17693 MGI:MGI:4937327 +100504608 Mettl21b Ensembl:ENSMUSG00000080115|Vega:OTTMUSG00000030578 +100504613 Gm17029 MGI:MGI:4937856 +100504616 Gm15910 MGI:MGI:3802158|Ensembl:ENSMUSG00000087480 +100504617 Strm MGI:MGI:1343201 +100504618 Gm11579 MGI:MGI:3650510 +100504619 Prox1os MGI:MGI:4937200 +100504626 Gm16364 MGI:MGI:3840142 +100504628 Gm20319 MGI:MGI:5012504|Ensembl:ENSMUSG00000092545 +100504629 Gm17669 MGI:MGI:4937303 +100504631 Vmn1r239-ps MGI:MGI:2148521 +100504632 Gm11478 MGI:MGI:3650888|Ensembl:ENSMUSG00000083992 +100504637 Gm20324 MGI:MGI:5012509|Ensembl:ENSMUSG00000100199 +100504638 Gm13341 MGI:MGI:3650228 +100504639 Gm20325 MGI:MGI:5012510 +100504640 Gm16089 MGI:MGI:3801884 +100504641 1700101I11Rik MGI:MGI:1915180|Ensembl:ENSMUSG00000097675 +100504642 Gm21996 MGI:MGI:5440224 +100504643 Gm20326 MGI:MGI:5012511 +100504644 Gm20327 MGI:MGI:5012512 +100504645 Gm20328 MGI:MGI:5012513 +100504650 A730085E03Rik MGI:MGI:2685598 +100504652 Gm12880 MGI:MGI:3651893 +100504653 4930555A03Rik MGI:MGI:1922587|Ensembl:ENSMUSG00000106157 +100504654 Gm10736 MGI:MGI:3704412 +100504659 Gm16210 MGI:MGI:3802077 +100504660 Gm20336 MGI:MGI:5012521 +100504661 Gm20337 MGI:MGI:5012522|Ensembl:ENSMUSG00000112880 +100504662 Gm20338 MGI:MGI:5012523 +100504663 Atg14 MGI:MGI:1261775|Ensembl:ENSMUSG00000037526 +100504666 Gm13551 MGI:MGI:3650818 +100504668 Gm20342 MGI:MGI:5012527 +100504669 Gm20343 MGI:MGI:5012528 +100504672 AA666905 MGI:MGI:3034728 +100504673 Gm20345 MGI:MGI:5012530 +100504674 Gm20346 MGI:MGI:5012531 +100504675 Gm15327 MGI:MGI:3705295 +100504679 Gm11951 MGI:MGI:3650315 +100504680 Gm20348 MGI:MGI:5012533 +100504687 2810029C07Rik MGI:MGI:1919920|Ensembl:ENSMUSG00000096995 +100504689 Plscr5 MGI:MGI:3779462|Ensembl:ENSMUSG00000095654|Vega:OTTMUSG00000046650 +100504692 Gm20356 MGI:MGI:5012541|Ensembl:ENSMUSG00000104096 +100504694 Gm12459 MGI:MGI:3651071 +100504699 9030425P06Rik MGI:MGI:2442528 +100504700 Gm15390 MGI:MGI:3705482 +100504701 Gm20362 MGI:MGI:5012547|Ensembl:ENSMUSG00000108072 +100504703 A730063M14Rik MGI:MGI:2443898|Ensembl:ENSMUSG00000112639 +100504710 Nat8f6 MGI:MGI:3779382|Ensembl:ENSMUSG00000079495|Vega:OTTMUSG00000034537 +100504711 Polr2k-ps MGI:MGI:3650073 +100504712 Gm20367 MGI:MGI:5012552 +100504713 Gm20368 MGI:MGI:5012553 +100504714 Gm16793 MGI:MGI:4439717|Ensembl:ENSMUSG00000097357 +100504715 Tmppe MGI:MGI:5317335|Ensembl:ENSMUSG00000079260|Vega:OTTMUSG00000062517 +100504716 Gm20369 MGI:MGI:5012554 +100504717 Gm12709 MGI:MGI:3651946|Ensembl:ENSMUSG00000085181 +100504719 Gm20371 MGI:MGI:5012556 +100504720 2310002F09Rik MGI:MGI:1916779 +100504724 Gm13510 MGI:MGI:3649639 +100504725 Gm20994 MGI:MGI:5434349 +100504727 BE692007 MGI:MGI:3035348 +100504728 Gm13985 MGI:MGI:3651939 +100504729 Gm13660 MGI:MGI:3649762 +100504731 Gm20377 MGI:MGI:5012562 +100504733 A730018C14Rik MGI:MGI:2442339|Ensembl:ENSMUSG00000047828 +100504734 Gm16794 MGI:MGI:4439718 +100504735 Gm20379 MGI:MGI:5012564 +100504738 Gm20381 MGI:MGI:5012566 +100504739 Gm20382 MGI:MGI:5012567 +100504740 Gm20383 MGI:MGI:5012568|Ensembl:ENSMUSG00000107412 +100504937 LOC100504937 - +100504950 Gm20997 MGI:MGI:5434352 +100505025 LOC100505025 Ensembl:ENSMUSG00000108530 +100505034 Gm29695 MGI:MGI:5588854 +100505096 Defa33 MGI:MGI:5434357|Ensembl:ENSMUSG00000094362|Vega:OTTMUSG00000062185 +100505199 LOC100505199 - +100505227 A430107J10Rik MGI:MGI:3708790 +100505265 Gm28645 MGI:MGI:5579351 +100505355 Gm15798 MGI:MGI:3802099 +100505380 Gm12196 MGI:MGI:3650409 +100505386 Gm21949 MGI:MGI:5439400|Ensembl:ENSMUSG00000102422|Vega:OTTMUSG00000051450 +100505397 Gm20385 MGI:MGI:5012570 +100510874 B930053N02Rik MGI:MGI:3648141 +100526460 Mir1264 MGI:MGI:4834216|Ensembl:ENSMUSG00000093122|miRBase:MI0004130 +100526461 Mir1249 MGI:MGI:4834217|Ensembl:ENSMUSG00000080441|miRBase:MI0004132 +100526462 Mir1298 MGI:MGI:4834221|Ensembl:ENSMUSG00000080331|miRBase:MI0004300 +100526463 Mir3058 MGI:MGI:4834226|Ensembl:ENSMUSG00000092867|miRBase:MI0004418 +100526464 Mir3106 MGI:MGI:4834227|Ensembl:ENSMUSG00000093142|miRBase:MI0004486 +100526465 Mir3057 MGI:MGI:4834230|Ensembl:ENSMUSG00000092781|miRBase:MI0014020 +100526466 Mir3060 MGI:MGI:4834232|Ensembl:ENSMUSG00000093080|miRBase:MI0014022 +100526467 Mir3061 MGI:MGI:4834233|Ensembl:ENSMUSG00000092870|miRBase:MI0014023 +100526468 Mir3063 MGI:MGI:4834235|Ensembl:ENSMUSG00000093358|miRBase:MI0014025 +100526469 Mir3064 MGI:MGI:4834237|Ensembl:ENSMUSG00000093273|miRBase:MI0014026 +100526470 Mir3066 MGI:MGI:4834239|Ensembl:ENSMUSG00000093037|miRBase:MI0014028 +100526471 Mir3069 MGI:MGI:4834242|Ensembl:ENSMUSG00000106366|miRBase:MI0014031 +100526472 Mir3070a MGI:MGI:4834243|Ensembl:ENSMUSG00000095147|miRBase:MI0014032 +100526473 Mir3071 MGI:MGI:4834245|Ensembl:ENSMUSG00000070129|miRBase:MI0014034 +100526474 Mir3074-1 MGI:MGI:4834247|Ensembl:ENSMUSG00000092741|miRBase:MI0014037 +100526475 Mir3076 MGI:MGI:4834249|Ensembl:ENSMUSG00000093156|miRBase:MI0014039 +100526476 Mir3077 MGI:MGI:4834250|Ensembl:ENSMUSG00000092784|miRBase:MI0014040 +100526477 Mir3080 MGI:MGI:4834253|Ensembl:ENSMUSG00000092751|miRBase:MI0014043 +100526478 Mir3081 MGI:MGI:4834254|Ensembl:ENSMUSG00000093046|miRBase:MI0014044 +100526479 Mir3082 MGI:MGI:4834255|Ensembl:ENSMUSG00000093076|miRBase:MI0014045 +100526480 Mir3086 MGI:MGI:4834260|Ensembl:ENSMUSG00000092813|miRBase:MI0014049 +100526481 Mir466m MGI:MGI:4834277|Ensembl:ENSMUSG00000092793|miRBase:MI0014050 +100526482 Mir466o MGI:MGI:4834279|Ensembl:ENSMUSG00000078026|miRBase:MI0014052 +100526483 Mir669a-5 MGI:MGI:4834282|Ensembl:ENSMUSG00000104734|miRBase:MI0014055 +100526485 Mir669a-6 MGI:MGI:4834283|Ensembl:ENSMUSG00000105330|miRBase:MI0014058 +100526486 Mir466b-4 MGI:MGI:4834285|Ensembl:ENSMUSG00000096239|miRBase:MI0014060 +100526488 Mir466b-5 MGI:MGI:4834360|Ensembl:ENSMUSG00000096113|miRBase:MI0014063 +100526489 Mir669a-8 MGI:MGI:4834288|Ensembl:ENSMUSG00000104652|miRBase:MI0014066 +100526490 Mir466b-6 MGI:MGI:4834289|Ensembl:ENSMUSG00000094261|miRBase:MI0014067 +100526491 Mir669a-9 MGI:MGI:4834290|Ensembl:ENSMUSG00000105182|miRBase:MI0014068 +100526492 Mir466b-7 MGI:MGI:4834291|Ensembl:ENSMUSG00000096360|miRBase:MI0014070 +100526494 Mir669a-10 MGI:MGI:4834293|Ensembl:ENSMUSG00000105365|miRBase:MI0014073 +100526495 Mir669a-11 MGI:MGI:4834295|Ensembl:ENSMUSG00000106488|miRBase:MI0014075 +100526496 Mir669a-12 MGI:MGI:4834297|Ensembl:ENSMUSG00000105783|miRBase:MI0014077 +100526497 Mir466p MGI:MGI:4834298|Ensembl:ENSMUSG00000077113|miRBase:MI0014078 +100526498 Mir3088 MGI:MGI:4834302|Ensembl:ENSMUSG00000092832|miRBase:MI0014081 +100526499 Mir3089 MGI:MGI:4834303|Ensembl:ENSMUSG00000093091|miRBase:MI0014082 +100526500 Mir3090 MGI:MGI:4834304|Ensembl:ENSMUSG00000093338|miRBase:MI0014083 +100526501 Mir3094 MGI:MGI:4834308|Ensembl:ENSMUSG00000092862|miRBase:MI0014087 +100526502 Mir3095 MGI:MGI:4834310|Ensembl:ENSMUSG00000093293|miRBase:MI0014088 +100526504 Mir3100 MGI:MGI:4834314|Ensembl:ENSMUSG00000092659|miRBase:MI0014092 +100526505 Mir3101 MGI:MGI:4834315|Ensembl:ENSMUSG00000093348|miRBase:MI0014093 +100526506 Mir344c MGI:MGI:4834318|Ensembl:ENSMUSG00000077107|miRBase:MI0014096 +100526507 Mir344g MGI:MGI:4834319|Ensembl:ENSMUSG00000092850|miRBase:MI0014097 +100526508 Mir3102 MGI:MGI:4834321|Ensembl:ENSMUSG00000093296|miRBase:MI0014099 +100526509 Mir3104 MGI:MGI:4834323|Ensembl:ENSMUSG00000092652|miRBase:MI0014101 +100526510 Mir3107 MGI:MGI:4834325|Ensembl:ENSMUSG00000106471|miRBase:MI0014103 +100526511 Mir3108 MGI:MGI:4834327|Ensembl:ENSMUSG00000093241|miRBase:MI0014105 +100526512 Mir3110 MGI:MGI:4834329|Ensembl:ENSMUSG00000092794|miRBase:MI0014107 +100526513 Mir374c MGI:MGI:4834330|Ensembl:ENSMUSG00000106465|miRBase:MI0014108 +100526514 Mir3112 MGI:MGI:4834331|Ensembl:ENSMUSG00000093172|miRBase:MI0014109 +100526515 Mir1247 MGI:MGI:4834215|Ensembl:ENSMUSG00000080356|miRBase:MI0004120 +100526516 Mir3059 MGI:MGI:4834225|Ensembl:ENSMUSG00000092952|miRBase:MI0004412 +100526517 Mir1251 MGI:MGI:4834231|Ensembl:ENSMUSG00000093227|miRBase:MI0014021 +100526518 Mir3065 MGI:MGI:4834238|Ensembl:ENSMUSG00000105524|miRBase:MI0014027 +100526519 Mir3070b MGI:MGI:4834244|Ensembl:ENSMUSG00000094952|miRBase:MI0014033 +100526520 Mir3078 MGI:MGI:4834251|Ensembl:ENSMUSG00000092972|miRBase:MI0014041 +100526521 Mir3084-1 MGI:MGI:5562753|Ensembl:ENSMUSG00000104890|miRBase:MI0014047 +100526524 Mir466n MGI:MGI:4834299|Ensembl:ENSMUSG00000077991|miRBase:MI0014079 +100526525 Mir3092 MGI:MGI:4834306|Ensembl:ENSMUSG00000092695|miRBase:MI0014085 +100526526 Mir3098 MGI:MGI:4834313|Ensembl:ENSMUSG00000093157|miRBase:MI0014091 +100526527 Mir344f MGI:MGI:4834320|Ensembl:ENSMUSG00000093108|miRBase:MI0014098 +100526528 Mir3074-2 MGI:MGI:4834326|Ensembl:ENSMUSG00000105458|miRBase:MI0014104 +100526529 Mir1912 MGI:MGI:4834332|Ensembl:ENSMUSG00000093039|miRBase:MI0014110 +100526530 Mir1843a MGI:MGI:4834219|Ensembl:ENSMUSG00000105972|miRBase:MI0004155 +100526531 Mir344d-2 MGI:MGI:4834229|Ensembl:ENSMUSG00000096893|miRBase:MI0004619 +100526532 Mir3067 MGI:MGI:4834240|Ensembl:ENSMUSG00000092673|miRBase:MI0014029 +100526533 Mir3075 MGI:MGI:4834248|Ensembl:ENSMUSG00000093081|miRBase:MI0014038 +100526534 Mir3083 MGI:MGI:4834256|Ensembl:ENSMUSG00000093118|miRBase:MI0014046 +100526535 Mir669a-4 MGI:MGI:4834281|Ensembl:ENSMUSG00000105546|miRBase:MI0014054 +100526536 Mir669a-7 MGI:MGI:4834286|Ensembl:ENSMUSG00000106027|miRBase:MI0014061 +100526538 Mir669p-2 MGI:MGI:4834292|Ensembl:ENSMUSG00000093900|miRBase:MI0014071 +100526539 Mir467a-10 MGI:MGI:4834296|Ensembl:ENSMUSG00000096894|miRBase:MI0014076 +100526540 Mir3093 MGI:MGI:4834307|Ensembl:ENSMUSG00000092988|miRBase:MI0014086 +100526541 Mir344e MGI:MGI:4834316|Ensembl:ENSMUSG00000077869|miRBase:MI0014094 +100526542 Mir3113 MGI:MGI:4834361|Ensembl:ENSMUSG00000093219|miRBase:MI0014111 +100526543 Mir344d-3 MGI:MGI:4834220|Ensembl:ENSMUSG00000095292|miRBase:MI0004227 +100526544 Mir344d-1 MGI:MGI:4834228|Ensembl:ENSMUSG00000092847|miRBase:MI0004524 +100526545 Mir3062 MGI:MGI:4834234|Ensembl:ENSMUSG00000092727|miRBase:MI0014024 +100526546 Mir3068 MGI:MGI:4834241|Ensembl:ENSMUSG00000105428|miRBase:MI0014030 +100526547 Mir3073a MGI:MGI:4834246|Ensembl:ENSMUSG00000093090|miRBase:MI0014036 +100526548 Mir3079 MGI:MGI:4834252|Ensembl:ENSMUSG00000093169|miRBase:MI0014042 +100526549 Mir3085 MGI:MGI:4834259|Ensembl:ENSMUSG00000093234|miRBase:MI0014048 +100526550 Mir669d-2 MGI:MGI:4834278|Ensembl:ENSMUSG00000080504|miRBase:MI0014051 +100526552 Mir669p-1 MGI:MGI:4834287|Ensembl:ENSMUSG00000096134|miRBase:MI0014064 +100526553 Mir467a-7 MGI:MGI:3719577|Ensembl:ENSMUSG00000094688|miRBase:MI0014069 +100526554 Mir467a-9 MGI:MGI:4834294|Ensembl:ENSMUSG00000095222|miRBase:MI0014074 +100526555 Mir3087 MGI:MGI:4834301|Ensembl:ENSMUSG00000104741|miRBase:MI0014080 +100526556 Mir3091 MGI:MGI:4834305|Ensembl:ENSMUSG00000092827|miRBase:MI0014084 +100526557 Mir3097 MGI:MGI:4834312|Ensembl:ENSMUSG00000093097|miRBase:MI0014090 +100526558 Mir344b MGI:MGI:4834317|Ensembl:ENSMUSG00000092921|miRBase:MI0014095 +100526559 Mir3103 MGI:MGI:4834322|Ensembl:ENSMUSG00000093215|miRBase:MI0014100 +100526560 Mir3109 MGI:MGI:4834328|Ensembl:ENSMUSG00000093042|miRBase:MI0014106 +100526561 Mir466b-8 MGI:MGI:4834333|Ensembl:ENSMUSG00000095269|miRBase:MI0014112 +100526562 Mir3105 MGI:MGI:4834324|Ensembl:ENSMUSG00000093221|miRBase:MI0014102 +100526665 Gm21006 MGI:MGI:5434361 +100526666 Gm21007 MGI:MGI:5434362 +100526691 LOC100526691 - +100526796 Cahm MGI:MGI:4462384 +100526822 Gm9778 MGI:MGI:3708558 +100529074 Snora33 MGI:MGI:3819501|Ensembl:ENSMUSG00000070063 +100529075 Snord100 MGI:MGI:3819514|Ensembl:ENSMUSG00000080486 +100529076 Snord42a MGI:MGI:3819532 +100529077 Snord42b MGI:MGI:3819533 +100529079 5830418P13Rik MGI:MGI:3604110|Ensembl:ENSMUSG00000086236 +100529082 Gm11127 MGI:MGI:3779381|Ensembl:ENSMUSG00000079492|Vega:OTTMUSG00000037503 +100532729 B430305J03Rik MGI:MGI:3697707 +100532730 C230037L18Rik MGI:MGI:3697701 +100534270 Gm21008 MGI:MGI:5434363 +100534271 Gm21009 MGI:MGI:5434364 +100534272 LOC100534272 - +100534273 Fer1l5 MGI:MGI:3616091|Ensembl:ENSMUSG00000037432|Vega:OTTMUSG00000033700 +100534274 LOC100534274 - +100534275 Gm14401 MGI:MGI:3650075 +100534276 Gm21998 MGI:MGI:5440227 +100534277 Gm21010 MGI:MGI:5434365 +100534278 LOC100534278 - +100534279 Gm21011 MGI:MGI:5434366 +100534280 Gm6914 MGI:MGI:3645060 +100534281 Gm21012 MGI:MGI:5434367 +100534282 Gm13130 MGI:MGI:3651258 +100534283 Gm13108 MGI:MGI:3650198 +100534285 Gm21013 MGI:MGI:5434368 +100534286 Gm21014 MGI:MGI:5434369 +100534287 LOC100534287 - +100534288 LOC100534288 - +100534290 LOC100534290 - +100534291 Gm21015 MGI:MGI:5434370 +100534292 Gm21016 MGI:MGI:5434371 +100534295 Gm21018 MGI:MGI:5434373 +100534296 LOC100534296 - +100534297 Gm21019 MGI:MGI:5434374 +100534298 Gm21020 MGI:MGI:5434375 +100534300 Gm20679 MGI:MGI:5313126 +100534301 LOC100534301 - +100534303 LOC100534303 - +100534305 Gm21021 MGI:MGI:5434376 +100534306 Gm21022 MGI:MGI:5434377 +100534307 Gm21023 MGI:MGI:5434378 +100534309 Gm21928 MGI:MGI:5439380 +100534310 Gm21929 MGI:MGI:5439381 +100534311 Gm21025 MGI:MGI:5434380 +100534312 LOC100534312 - +100534313 Gm21026 MGI:MGI:5434381 +100534314 Gm21027 MGI:MGI:5434382 +100534315 LOC100534315 - +100534316 Gm21028 MGI:MGI:5434383 +100534317 LOC100534317 - +100534321 Gm21930 MGI:MGI:5439382 +100534322 Gm38428 MGI:MGI:5621313 +100534324 Gm21029 MGI:MGI:5434384 +100534325 Gm38429 MGI:MGI:5621314 +100534326 Gm21931 MGI:MGI:5439383 +100534327 Gm12080 MGI:MGI:3650552 +100534330 LOC100534330 - +100534331 LOC100534331 - +100534332 Gm21030 MGI:MGI:5434385 +100534333 Gm21031 MGI:MGI:5434386 +100534336 LOC100534336 - +100534340 LOC100534340 - +100534341 Gm21032 MGI:MGI:5434387 +100534342 Gm21033 MGI:MGI:5434388 +100534343 Gm21034 MGI:MGI:5434389 +100534344 Gm21035 MGI:MGI:5434390 +100534345 Gm21036 MGI:MGI:5434391 +100534346 Gm21037 MGI:MGI:5434392 +100534347 LOC100534347 - +100534349 Gm21038 MGI:MGI:5434393 +100534350 Gm21039 MGI:MGI:5434394 +100534352 Gm38430 MGI:MGI:5621315 +100534353 LOC100534353 - +100534354 LOC100534354 - +100534356 Gm21040 MGI:MGI:5434395 +100534357 LOC100534357 - +100534358 LOC100534358 - +100534360 Gm21041 MGI:MGI:5434396 +100534361 Gm21042 MGI:MGI:5434397 +100534363 Gm21043 MGI:MGI:5434398 +100534365 LOC100534365 - +100534366 Gm21045 MGI:MGI:5434400 +100534370 LOC100534370 - +100534371 LOC100534371 - +100534373 Gm15833 MGI:MGI:3801794 +100534374 Gm21046 MGI:MGI:5434401 +100534376 LOC100534376 - +100534377 LOC100534377 - +100534378 Gm21047 MGI:MGI:5434402 +100534379 Gm21048 MGI:MGI:5434403 +100534380 LOC100534380 - +100534381 Gm21049 MGI:MGI:5434404 +100534382 Gm21050 MGI:MGI:5434405 +100534383 LOC100534383 - +100534384 Gm21051 MGI:MGI:5434406 +100534385 LOC100534385 - +100534386 LOC100534386 - +100534387 LOC100534387 - +100534388 LOC100534388 - +100534389 LOC100534389 - +100534390 LOC100534390 - +100534391 LOC100534391 - +100534392 Gm21052 MGI:MGI:5434407 +100534393 LOC100534393 - +100534622 Gm17449 MGI:MGI:4937083 +100534633 Gm15008 MGI:MGI:3705107|Ensembl:ENSMUSG00000087155 +100534641 Gm13856 MGI:MGI:3652199 +100551508 Gm17344 MGI:MGI:4936978 +100568458 Gm38431 MGI:MGI:5621316 +100568459 Bc1 MGI:MGI:104905 +100579137 Dmrt1i MGI:MGI:4887388|Ensembl:ENSMUSG00000104600 +100579147 Gm10619 MGI:MGI:3708756|Ensembl:ENSMUSG00000074067 +100579148 Gm17409 MGI:MGI:4937043 +100579149 Gm17416 MGI:MGI:4937050 +100579150 Gm17618 MGI:MGI:4937252 +100579151 Gm16833 MGI:MGI:4439757|Ensembl:ENSMUSG00000085253 +100579154 Gm17324 MGI:MGI:4936958 +100579155 Gm17590 MGI:MGI:4937224 +100616072 Snord116 MGI:MGI:1891407 +100616095 Snhg18 MGI:MGI:1914085|Ensembl:ENSMUSG00000096956 +100628567 Mir28c MGI:MGI:4950386|Ensembl:ENSMUSG00000104794|miRBase:MI0016966 +100628568 Mir3963 MGI:MGI:4950402|Ensembl:ENSMUSG00000092830|miRBase:MI0016968 +100628570 Mir3965 MGI:MGI:4950404|Ensembl:ENSMUSG00000093311|miRBase:MI0016972 +100628571 Mir378b MGI:MGI:4950393|Ensembl:ENSMUSG00000092985|miRBase:MI0016973 +100628572 Mir101c MGI:MGI:4950030|Ensembl:ENSMUSG00000106183|miRBase:MI0016974 +100628573 Mir3969 MGI:MGI:4950408|Ensembl:ENSMUSG00000106074|miRBase:MI0016978 +100628574 Mir28b MGI:MGI:4950385|Ensembl:ENSMUSG00000093140|miRBase:MI0016979 +100628575 Mir3970 MGI:MGI:4950409|Ensembl:ENSMUSG00000106278|miRBase:MI0016980 +100628576 Mir5046 MGI:MGI:4950413|Ensembl:ENSMUSG00000104884|miRBase:MI0017931 +100628577 Mir5098 MGI:MGI:4950415|Ensembl:ENSMUSG00000093061|miRBase:MI0018006 +100628578 Mir5099 MGI:MGI:4950417|Ensembl:ENSMUSG00000092998|miRBase:MI0018007 +100628580 Mir5103 MGI:MGI:4950423|Ensembl:ENSMUSG00000092852|miRBase:MI0018011 +100628581 Mir5104 MGI:MGI:4950424|Ensembl:ENSMUSG00000093060|miRBase:MI0018012 +100628582 Mir3473c MGI:MGI:4950389|Ensembl:ENSMUSG00000093003|miRBase:MI0018015 +100628583 Mir5108 MGI:MGI:4950428|Ensembl:ENSMUSG00000093017|miRBase:MI0018017 +100628586 Mir5112 MGI:MGI:4950432|Ensembl:ENSMUSG00000092638|miRBase:MI0018021 +100628589 Mir5118 MGI:MGI:4950438|Ensembl:ENSMUSG00000093292|miRBase:MI0018027 +100628590 Mir5120 MGI:MGI:4950445|Ensembl:ENSMUSG00000092761|miRBase:MI0018029 +100628591 Mir466q MGI:MGI:4950412|Ensembl:ENSMUSG00000092990|miRBase:MI0018032 +100628592 Mir3473d MGI:MGI:4950390|Ensembl:ENSMUSG00000093087|miRBase:MI0018033 +100628593 Mir5125 MGI:MGI:4950450|Ensembl:ENSMUSG00000092981|miRBase:MI0018036 +100628594 Mir3572 MGI:MGI:4950392|Ensembl:ENSMUSG00000093290|miRBase:MI0018037 +100628595 Mir5126 MGI:MGI:4950451|Ensembl:ENSMUSG00000093254|miRBase:MI0018038 +100628596 Mir5127 MGI:MGI:4950452|Ensembl:ENSMUSG00000093036|miRBase:MI0018039 +100628597 Mir5128 MGI:MGI:4950453|Ensembl:ENSMUSG00000092958|miRBase:MI0018040 +100628598 Mir5129 MGI:MGI:4950454|Ensembl:ENSMUSG00000092679|miRBase:MI0018041 +100628599 Mir5130 MGI:MGI:4950455|Ensembl:ENSMUSG00000092901|miRBase:MI0018042 +100628600 Mir5131 MGI:MGI:4950456|Ensembl:ENSMUSG00000093167|miRBase:MI0018043 +100628601 Mir5132 MGI:MGI:4950457|Ensembl:ENSMUSG00000092907|miRBase:MI0018044 +100628602 Mir5133 MGI:MGI:4950458|Ensembl:ENSMUSG00000092696|miRBase:MI0018045 +100628603 Mir5134 MGI:MGI:4950459|Ensembl:ENSMUSG00000093270|miRBase:MI0018046 +100628604 Mir5135 MGI:MGI:4950460|Ensembl:ENSMUSG00000092738|miRBase:MI0018047 +100628605 Mir5136 MGI:MGI:4950461|Ensembl:ENSMUSG00000093314|miRBase:MI0018048 +100628606 Mir3960 MGI:MGI:4950394|Ensembl:ENSMUSG00000105841|miRBase:MI0016963 +100628607 Mir3964 MGI:MGI:4950403|Ensembl:ENSMUSG00000092639|miRBase:MI0016970 +100628608 Mir3967 MGI:MGI:4950406|Ensembl:ENSMUSG00000106199|miRBase:MI0016976 +100628609 Mir3473b MGI:MGI:4950388|Ensembl:ENSMUSG00000093298|miRBase:MI0016997 +100628610 Mir5101 MGI:MGI:4950421|Ensembl:ENSMUSG00000092922|miRBase:MI0018009 +100628611 Mir5107 MGI:MGI:4950427|Ensembl:ENSMUSG00000093327|miRBase:MI0018016 +100628612 Mir5113 MGI:MGI:4950433|Ensembl:ENSMUSG00000092868|miRBase:MI0018022 +100628613 Mir5119 MGI:MGI:4950444|Ensembl:ENSMUSG00000093176|miRBase:MI0018028 +100628614 Mir5123 MGI:MGI:4950448|Ensembl:ENSMUSG00000096377|miRBase:MI0018034 +100628615 Mir3962 MGI:MGI:4950397|Ensembl:ENSMUSG00000092633|miRBase:MI0016967 +100628616 Mir3966 MGI:MGI:4950405|Ensembl:ENSMUSG00000105557|miRBase:MI0016975 +100628618 Mir5106 MGI:MGI:4950426|Ensembl:ENSMUSG00000092677|miRBase:MI0018014 +100628619 Mir5114 MGI:MGI:4950434|Ensembl:ENSMUSG00000093315|miRBase:MI0018023 +100628620 Mir5122 MGI:MGI:4950447|Ensembl:ENSMUSG00000092745|miRBase:MI0018031 +100628621 Mir3961 MGI:MGI:4950395|Ensembl:ENSMUSG00000106655|miRBase:MI0016965 +100628622 Mir1843b MGI:MGI:4950384|Ensembl:ENSMUSG00000105399|miRBase:MI0016971 +100628623 Mir3968 MGI:MGI:4950407|Ensembl:ENSMUSG00000093096|miRBase:MI0016977 +100628624 Mir3971 MGI:MGI:4950411|Ensembl:ENSMUSG00000093100|miRBase:MI0016981 +100628625 Mir5100 MGI:MGI:4950420|Ensembl:ENSMUSG00000092734|miRBase:MI0018008 +100628627 Mir5110 MGI:MGI:4950430|Ensembl:ENSMUSG00000093278|miRBase:MI0018019 +100628628 Mir5116 MGI:MGI:4950436|Ensembl:ENSMUSG00000092787|miRBase:MI0018025 +100628629 Mir5121 MGI:MGI:4950446|Ensembl:ENSMUSG00000105913|miRBase:MI0018030 +100628630 Mir5124a MGI:MGI:4950449|Ensembl:ENSMUSG00000093269|miRBase:MI0018035 +100642166 Gm15446 MGI:MGI:3709333|Ensembl:ENSMUSG00000090015 +100642183 Gm13662 MGI:MGI:3650471 +100653389 Mir155hg MGI:MGI:5477161|Ensembl:ENSMUSG00000097418 +100653392 Gm4149 MGI:MGI:3782325 +100689012 Gm29696 MGI:MGI:5588855 +100689703 9330133O14Rik MGI:MGI:2442309 +100736249 Mira MGI:MGI:5433747 +100750327 Gm10226 MGI:MGI:3704470 +100775172 Ighv8-13 MGI:MGI:4439734|IMGT/GENE-DB:IGHV8-13 +100775173 Ighv1-74 MGI:MGI:4439634|IMGT/GENE-DB:IGHV1-74 +100775174 Ighv1-76 MGI:MGI:4439737|IMGT/GENE-DB:IGHV1-76 +100775175 Ighv1-82 MGI:MGI:4439671|IMGT/GENE-DB:IGHV1-82 +100775176 Ighv8-15 MGI:MGI:5434408|IMGT/GENE-DB:IGHV8-15 +100775177 Ighv8-16 MGI:MGI:5434409|IMGT/GENE-DB:IGHV8-16 +100820711 D430050E20Rik MGI:MGI:3041223 +100846986 Pou5f1-rs1 MGI:MGI:101892 +100846987 Pou5f1-rs5 MGI:MGI:101888 +100846988 Gm21055 MGI:MGI:5434412 +100846989 Gm11366 MGI:MGI:3652075 +100852391 Gm13319 MGI:MGI:3651285 +100852392 Gm21056 MGI:MGI:5434413 +100856803 Gm8265 MGI:MGI:3779792 +100856880 Gm9870 MGI:MGI:3708720 +100859929 Krtap3 - +100859931 Gm20604 MGI:MGI:5305180|Ensembl:ENSMUSG00000041716|Vega:OTTMUSG00000042331 +100859962 Gm21057 MGI:MGI:5434414|Ensembl:ENSMUSG00000108714 +100861471 n-R5s100 MGI:MGI:4421948|Ensembl:ENSMUSG00000094720 +100861472 n-R5s103 MGI:MGI:4421951|Ensembl:ENSMUSG00000095249 +100861473 n-R5s104 MGI:MGI:4421952|Ensembl:ENSMUSG00000096307 +100861474 n-R5s105 MGI:MGI:4421953|Ensembl:ENSMUSG00000095966 +100861475 n-R5s108 MGI:MGI:4421956|Ensembl:ENSMUSG00000096335 +100861477 n-R5s110 MGI:MGI:4421958|Ensembl:ENSMUSG00000095131 +100861478 n-R5s111 MGI:MGI:4421959|Ensembl:ENSMUSG00000094097 +100861479 n-R5s113 MGI:MGI:4421961|Ensembl:ENSMUSG00000094801 +100861480 Gm25018 MGI:MGI:5454795|Ensembl:ENSMUSG00000094751 +100861481 n-R5s117 MGI:MGI:4421967|Ensembl:ENSMUSG00000096710 +100861482 n-R5s121 MGI:MGI:4421973|Ensembl:ENSMUSG00000095410 +100861483 n-R5s122 MGI:MGI:4421974|Ensembl:ENSMUSG00000094956 +100861484 n-R5s123 MGI:MGI:4421975|Ensembl:ENSMUSG00000095652 +100861486 n-R5s124 MGI:MGI:4421976|Ensembl:ENSMUSG00000093893 +100861487 n-R5s128 MGI:MGI:4421984|Ensembl:ENSMUSG00000094003 +100861488 Gm26391 MGI:MGI:5456168|Ensembl:ENSMUSG00000094916 +100861489 n-R5s133 MGI:MGI:4421989|Ensembl:ENSMUSG00000096343 +100861490 n-R5s134 MGI:MGI:4421990|Ensembl:ENSMUSG00000096015 +100861491 n-R5s136 MGI:MGI:4421992|Ensembl:ENSMUSG00000096037 +100861492 n-R5s138 MGI:MGI:4421994|Ensembl:ENSMUSG00000095183 +100861493 n-R5s139 MGI:MGI:4421995|Ensembl:ENSMUSG00000094760 +100861494 Gm22109 MGI:MGI:5451886|Ensembl:ENSMUSG00000095376 +100861495 n-R5s141 MGI:MGI:4421997|Ensembl:ENSMUSG00000095749 +100861496 n-R5s142 MGI:MGI:4421998|Ensembl:ENSMUSG00000094657 +100861497 n-R5s143 MGI:MGI:4421999|Ensembl:ENSMUSG00000095645 +100861498 n-R5s144 MGI:MGI:4422000|Ensembl:ENSMUSG00000096765 +100861499 Gm25212 MGI:MGI:5454989|Ensembl:ENSMUSG00000096300 +100861500 n-R5s146 MGI:MGI:4422002|Ensembl:ENSMUSG00000096170 +100861501 Gm22291 MGI:MGI:5452068|Ensembl:ENSMUSG00000094270 +100861502 Gm23284 MGI:MGI:5453061|Ensembl:ENSMUSG00000095350 +100861503 n-R5s149 MGI:MGI:4422007|Ensembl:ENSMUSG00000095453 +100861531 Rn45s - +100861570 DQ267100 MGI:MGI:5439865|Ensembl:ENSMUSG00000084549 +100861571 DQ267101 MGI:MGI:5439874|Ensembl:ENSMUSG00000064496 +100861572 DQ267102 MGI:MGI:5439880|Ensembl:ENSMUSG00000064417 +100861575 Gm13161 MGI:MGI:3650656 +100861594 Gm21061 MGI:MGI:5434416 +100861596 Gm21062 MGI:MGI:5434417 +100861597 Gm21063 MGI:MGI:5434418 +100861598 Gm21064 MGI:MGI:5434419 +100861599 Gm21065 MGI:MGI:5434420 +100861605 Gm21070 MGI:MGI:5434425 +100861610 Gm21075 MGI:MGI:5434430 +100861611 Gm21076 MGI:MGI:5434431 +100861615 LOC100861615 Ensembl:ENSMUSG00000079396|Vega:OTTMUSG00000036168 +100861618 LOC100861618 - +100861620 Gm21082 MGI:MGI:5434437 +100861621 Gm21083 MGI:MGI:5434438 +100861623 Rhox3a2 MGI:MGI:5434440|Ensembl:ENSMUSG00000095601|Vega:OTTMUSG00000044439 +100861626 Gm21933 MGI:MGI:5439384 +100861627 LOC100861627 - +100861630 Gm21088 MGI:MGI:5434443 +100861631 Gm21089 MGI:MGI:5434444 +100861634 Gm21092 MGI:MGI:5434447 +100861635 Gm21093 MGI:MGI:5434448 +100861637 Gm21095 MGI:MGI:5434450|Ensembl:ENSMUSG00000095153|Vega:OTTMUSG00000046872 +100861640 Rhox4a2 MGI:MGI:5434453|Ensembl:ENSMUSG00000094945|Vega:OTTMUSG00000044440 +100861646 Gm21103 MGI:MGI:5434458 +100861647 Gm21104 MGI:MGI:5434459 +100861651 LOC100861651 - +100861655 LOC100861655 - +100861656 Gm21110 MGI:MGI:5434465 +100861659 Gm21111 MGI:MGI:5434466 +100861660 Gm21112 MGI:MGI:5434467 +100861662 Gm21114 MGI:MGI:5434469 +100861663 Gm21115 MGI:MGI:5434470 +100861665 Gm21117 MGI:MGI:5434472 +100861666 Gm21935 MGI:MGI:5439386 +100861667 Gm21118 MGI:MGI:5434473|Ensembl:ENSMUSG00000094052|Vega:OTTMUSG00000046000 +100861668 Gm21119 MGI:MGI:5434474|Ensembl:ENSMUSG00000095294|Vega:OTTMUSG00000062180 +100861672 Gm21122 MGI:MGI:5434477 +100861673 Gm21123 MGI:MGI:5434478|Ensembl:ENSMUSG00000109700 +100861677 Gm21127 MGI:MGI:5434482 +100861679 Gm21129 MGI:MGI:5434484 +100861683 Gm21133 MGI:MGI:5434488 +100861685 Gm21135 MGI:MGI:5434490 +100861686 Gm21136 MGI:MGI:5434491 +100861690 Gm21139 MGI:MGI:5434494 +100861691 LOC100861691 - +100861694 Gm21142 MGI:MGI:5434497 +100861698 Gm21145 MGI:MGI:5434500 +100861700 Gm21147 MGI:MGI:5434502 +100861702 Gm21149 MGI:MGI:5434504|Ensembl:ENSMUSG00000099762|Vega:OTTMUSG00000055278 +100861704 Gm21151 MGI:MGI:5434506 +100861705 Gm21152 MGI:MGI:5434507 +100861708 Gm21154 MGI:MGI:5434509 +100861709 Gm21155 MGI:MGI:5434510 +100861713 Gm21156 MGI:MGI:5434511 +100861715 Gm21158 MGI:MGI:5434513 +100861717 Gm21160 MGI:MGI:5434515 +100861719 Gm21162 MGI:MGI:5434517 +100861720 Gm21163 MGI:MGI:5434518 +100861727 LOC100861727 - +100861728 Gm21168 MGI:MGI:5434523 +100861730 Gm21170 MGI:MGI:5434525 +100861731 Gm21171 MGI:MGI:5434526 +100861734 Gm21173 MGI:MGI:5434528 +100861738 LOC100861738 - +100861741 Gm21178 MGI:MGI:5434533 +100861743 Gm21180 MGI:MGI:5434535 +100861744 Gm21181 MGI:MGI:5434536 +100861746 Gm21183 MGI:MGI:5434538 +100861747 Gm5385 MGI:MGI:3644448 +100861748 Gm21184 MGI:MGI:5434539 +100861749 LOC100861749 - +100861753 Gm21188 MGI:MGI:5434543|Ensembl:ENSMUSG00000095609 +100861755 Gm21190 MGI:MGI:5434545|Ensembl:ENSMUSG00000106445|Vega:OTTMUSG00000055280 +100861756 Gm21191 MGI:MGI:5434546 +100861766 Gm16755 MGI:MGI:4439679 +100861769 Gm21201 MGI:MGI:5434556 +100861779 Gm21209 MGI:MGI:5434564 +100861784 LOC100861784 - +100861794 Gm21221 MGI:MGI:5434576|Ensembl:ENSMUSG00000106740 +100861806 Gm21232 MGI:MGI:5434587 +100861814 LOC100861814 - +100861817 Gm21242 MGI:MGI:5434597 +100861820 Gm21244 MGI:MGI:5434599 +100861821 Gm21245 MGI:MGI:5434600 +100861824 Gm21247 MGI:MGI:5434602 +100861825 Gm21248 MGI:MGI:5434603 +100861828 Gm21249 MGI:MGI:5434604 +100861836 Gm21257 MGI:MGI:5434612 +100861839 Gm21258 MGI:MGI:5434613|Ensembl:ENSMUSG00000095606|Vega:OTTMUSG00000048476 +100861850 Gm21268 MGI:MGI:5434623 +100861851 Gm21269 MGI:MGI:5434624 +100861855 Gm16170 MGI:MGI:3805548 +100861860 Gm21275 MGI:MGI:5434630 +100861861 Gm21276 MGI:MGI:5434631 +100861867 Gm21281 MGI:MGI:5434636 +100861868 Gm21282 MGI:MGI:5434637 +100861869 Gm21283 MGI:MGI:5434638 +100861870 Gm21284 MGI:MGI:5434639|Ensembl:ENSMUSG00000108660 +100861871 Gm21285 MGI:MGI:5434640 +100861873 Gm21287 MGI:MGI:5434642 +100861879 Gm21292 MGI:MGI:5434647|Ensembl:ENSMUSG00000091077|Vega:OTTMUSG00000046154 +100861880 Gm21293 MGI:MGI:5434648|Ensembl:ENSMUSG00000091779|Vega:OTTMUSG00000042978 +100861881 Gm21294 MGI:MGI:5434649 +100861884 Gm21297 MGI:MGI:5434652 +100861888 Gm21301 MGI:MGI:5434656 +100861889 Gm21302 MGI:MGI:5434657 +100861891 Gm21304 MGI:MGI:5434659|Ensembl:ENSMUSG00000097550|Vega:OTTMUSG00000042981 +100861896 Gm21308 MGI:MGI:5434663 +100861898 Gm21936 MGI:MGI:5439387|Ensembl:ENSMUSG00000113201|Vega:OTTMUSG00000042986 +100861899 Gm21310 MGI:MGI:5434665|Ensembl:ENSMUSG00000095032|Vega:OTTMUSG00000046755 +100861901 Gm21312 MGI:MGI:5434667|Ensembl:ENSMUSG00000094144|Vega:OTTMUSG00000042982 +100861905 Gm21316 MGI:MGI:5434671 +100861906 Gm21317 MGI:MGI:5434672|Ensembl:ENSMUSG00000101286|Vega:OTTMUSG00000046741 +100861908 Gm21319 MGI:MGI:5434674|Ensembl:ENSMUSG00000095724|Vega:OTTMUSG00000042985 +100861909 Gm21320 MGI:MGI:5434675|Ensembl:ENSMUSG00000110439|Vega:OTTMUSG00000061742 +100861911 Gm21321 MGI:MGI:5434676 +100861913 LOC100861913 - +100861915 Gm21937 MGI:MGI:5439388 +100861923 Gm21330 MGI:MGI:5434685 +100861928 Gm21333 MGI:MGI:5434688 +100861933 LOC100861933 - +100861937 Gm21340 MGI:MGI:5434695 +100861942 Gm21344 MGI:MGI:5434699 +100861947 Gm13123 MGI:MGI:3651473 +100861962 Gm21358 MGI:MGI:5434713 +100861966 Btbd35f23 MGI:MGI:5439401|Ensembl:ENSMUSG00000100249|Vega:OTTMUSG00000042958 +100861968 Gm21362 MGI:MGI:5434717 +100861969 LOC100861969 Ensembl:ENSMUSG00000095456 +100861971 Btbd35f24 MGI:MGI:5434719 +100861973 Gm21366 MGI:MGI:5434721|Ensembl:ENSMUSG00000103919|Vega:OTTMUSG00000050112 +100861977 Gm21370 MGI:MGI:5434725 +100861978 LOC100861978 Ensembl:ENSMUSG00000095247 +100861986 Gm21378 MGI:MGI:5434733 +100861987 Gm21379 MGI:MGI:5434734 +100861988 Gm21380 MGI:MGI:5434735 +100861997 Gm21387 MGI:MGI:5434742 +100861998 Gm21388 MGI:MGI:5434743 +100862003 Gm21392 MGI:MGI:5434747 +100862005 Gm21393 MGI:MGI:5434748 +100862009 Gm21396 MGI:MGI:5434751 +100862012 Gm21399 MGI:MGI:5434754 +100862015 Gm11236 MGI:MGI:3702277|Ensembl:ENSMUSG00000096700|Vega:OTTMUSG00000000280 +100862019 Gm21404 MGI:MGI:5434759 +100862020 Gm21405 MGI:MGI:5434760 +100862025 Gm21409 MGI:MGI:5434764|Ensembl:ENSMUSG00000099840|Vega:OTTMUSG00000046908 +100862028 Gm21412 MGI:MGI:5434767 +100862029 Gm21413 MGI:MGI:5434768 +100862036 Gm21419 MGI:MGI:5434774 +100862037 Gm21420 MGI:MGI:5434775 +100862042 Gm21425 MGI:MGI:5434780|Ensembl:ENSMUSG00000096820|Vega:OTTMUSG00000050532 +100862043 LOC100862043 - +100862045 Gm21427 MGI:MGI:5434782 +100862046 Gm21428 MGI:MGI:5434783 +100862048 Gm21430 MGI:MGI:5434785 +100862050 Gm21432 MGI:MGI:5434787 +100862053 Gm21435 MGI:MGI:5434790 +100862059 Gm21440 MGI:MGI:5434795|Ensembl:ENSMUSG00000103468|Vega:OTTMUSG00000050534 +100862062 Gm21443 MGI:MGI:5434798 +100862066 Cfap99 MGI:MGI:5434801|Ensembl:ENSMUSG00000109572|Vega:OTTMUSG00000059276 +100862067 Btbd35f29 MGI:MGI:5434802|Ensembl:ENSMUSG00000094391 +100862071 Gm21450 MGI:MGI:5434805 +100862072 Gm21451 MGI:MGI:5434806|Ensembl:ENSMUSG00000094526 +100862075 Gm21454 MGI:MGI:5434809|Ensembl:ENSMUSG00000093903|Vega:OTTMUSG00000050537 +100862082 Gm21461 MGI:MGI:5434816 +100862083 Gm21462 MGI:MGI:5434817 +100862085 Gm16867 MGI:MGI:4439791 +100862088 Gm21466 MGI:MGI:5434821 +100862091 Gm21469 MGI:MGI:5434824 +100862092 Gm21470 MGI:MGI:5434825 +100862097 Gm38432 MGI:MGI:5621317 +100862099 Gm21476 MGI:MGI:5434831 +100862100 Gm21477 MGI:MGI:5434832 +100862105 Gm14601 MGI:MGI:3705772 +100862106 LOC100862106 - +100862113 Gm21488 MGI:MGI:5434843 +100862114 Gm21489 MGI:MGI:5434844 +100862115 LOC100862115 Ensembl:ENSMUSG00000095666 +100862118 Spin2e MGI:MGI:5434847|Ensembl:ENSMUSG00000096645 +100862119 Gm14387 MGI:MGI:3650318 +100862122 LOC100862122 - +100862124 Gm15026 MGI:MGI:3705439 +100862125 Gm21497 MGI:MGI:5434852 +100862126 Defa36 MGI:MGI:5434853|Ensembl:ENSMUSG00000094662|Vega:OTTMUSG00000061984 +100862135 Gm21506 MGI:MGI:5434861 +100862142 Gm21513 MGI:MGI:5434868 +100862147 Gm21518 MGI:MGI:5434873 +100862150 LOC100862150 - +100862156 Gm21524 MGI:MGI:5434879 +100862161 Gm21529 MGI:MGI:5434884 +100862162 Gm21530 MGI:MGI:5434885 +100862173 Gm21539 MGI:MGI:5434894 +100862175 Gm10698 MGI:MGI:3704329 +100862177 Gm21541 MGI:MGI:5434896|Ensembl:ENSMUSG00000094065|Vega:OTTMUSG00000011347 +100862178 Gm21542 MGI:MGI:5434897 +100862179 LOC100862179 - +100862180 LOC100862180 - +100862192 LOC100862192 Ensembl:ENSMUSG00000096236 +100862202 LOC100862202 Ensembl:ENSMUSG00000096756 +100862203 Gm6712 MGI:MGI:3645888 +100862204 LOC100862204 - +100862206 Gm21559 MGI:MGI:5434914 +100862207 Gm21560 MGI:MGI:5434915 +100862209 Gm21562 MGI:MGI:5434917 +100862220 LOC100862220 Ensembl:ENSMUSG00000079773 +100862221 Gm21569 MGI:MGI:5434924 +100862223 Gm21571 MGI:MGI:5434926 +100862224 Gm21572 MGI:MGI:5434927 +100862225 Gm21573 MGI:MGI:5434928 +100862231 Gm21939 MGI:MGI:5439390 +100862233 Gm21577 MGI:MGI:5434932 +100862239 Spin2g MGI:MGI:5434937 +100862242 LOC100862242 - +100862244 Gm21940 MGI:MGI:5439391 +100862245 LOC100862245 Ensembl:ENSMUSG00000094722 +100862247 Gm21586 MGI:MGI:5434941|Ensembl:ENSMUSG00000095234 +100862249 LOC100862249 - +100862250 Gm21588 MGI:MGI:5434943 +100862258 Gm21596 MGI:MGI:5434951 +100862261 Fam205a3 MGI:MGI:5434953|Ensembl:ENSMUSG00000093996 +100862262 Gm21599 MGI:MGI:5434954 +100862268 LOC100862268 Ensembl:ENSMUSG00000097456 +100862271 LOC100862271 - +100862274 Btbd35f25 MGI:MGI:5434963|Ensembl:ENSMUSG00000095637 +100862280 Gm21614 MGI:MGI:5434969 +100862282 Gm21616 MGI:MGI:5434971 +100862283 Gm21617 MGI:MGI:5434972 +100862287 LOC100862287 - +100862288 Gm21620 MGI:MGI:5434975 +100862296 Gm21626 MGI:MGI:5434981 +100862297 Gm21627 MGI:MGI:5434982 +100862302 Gm21631 MGI:MGI:5434986 +100862310 Gm21633 MGI:MGI:5434988 +100862311 Gm21634 MGI:MGI:5434989 +100862314 Gm21637 MGI:MGI:5434992|Ensembl:ENSMUSG00000095770|Vega:OTTMUSG00000042961 +100862315 Gm21638 MGI:MGI:5434993 +100862320 Gm21642 MGI:MGI:5434997 +100862323 Btbd35f22 MGI:MGI:5435000|Ensembl:ENSMUSG00000093857 +100862324 LOC100862324 Ensembl:ENSMUSG00000079774 +100862326 Gm21647 MGI:MGI:5435002 +100862329 Btbd35f21 MGI:MGI:5439402|Ensembl:ENSMUSG00000099711|Vega:OTTMUSG00000042960 +100862330 Gm21650 MGI:MGI:5435005 +100862336 Gm21654 MGI:MGI:5435009 +100862337 LOC100862337 - +100862339 Gm21655 MGI:MGI:5435010 +100862341 Btbd35f30 MGI:MGI:5435012|Ensembl:ENSMUSG00000094361 +100862342 Gm21658 MGI:MGI:5435013 +100862345 Gm21660 MGI:MGI:5435015 +100862346 Gm21661 MGI:MGI:5435016 +100862348 Gm9295 MGI:MGI:3648889 +100862349 Gm21663 MGI:MGI:5435018|Ensembl:ENSMUSG00000104824|Vega:OTTMUSG00000053849 +100862352 Gm29697 MGI:MGI:5588856 +100862359 Gm21671 MGI:MGI:5435026|Ensembl:ENSMUSG00000095550|Vega:OTTMUSG00000053850 +100862360 Gm21672 MGI:MGI:5435027 +100862361 Gm21673 MGI:MGI:5435028 +100862365 Gm21677 MGI:MGI:5435032|Ensembl:ENSMUSG00000093918|Vega:OTTMUSG00000045462 +100862366 Gm21678 MGI:MGI:5435033 +100862367 Gm21679 MGI:MGI:5435034 +100862368 Gm21680 MGI:MGI:5435035|Ensembl:ENSMUSG00000106627|Vega:OTTMUSG00000053852 +100862369 Btbd35f9 MGI:MGI:5435036|Ensembl:ENSMUSG00000095558 +100862371 Gm21683 MGI:MGI:5435038 +100862372 LOC100862372 - +100862374 LOC100862374 - +100862375 Entpd4b MGI:MGI:5435040|Ensembl:ENSMUSG00000022066|Vega:OTTMUSG00000044499 +100862381 Gm21691 MGI:MGI:5435046 +100862383 Gm21693 MGI:MGI:5435048|Ensembl:ENSMUSG00000094511|Vega:OTTMUSG00000045464 +100862388 Gm21698 MGI:MGI:5435053|Ensembl:ENSMUSG00000096045|Vega:OTTMUSG00000047924 +100862389 Btbd35f8 MGI:MGI:5435054|Ensembl:ENSMUSG00000094155 +100862394 Gm21704 MGI:MGI:5435059|Ensembl:ENSMUSG00000093987|Vega:OTTMUSG00000045466 +100862398 Gm21708 MGI:MGI:5435063|Ensembl:ENSMUSG00000095948|Vega:OTTMUSG00000045468 +100862400 Gm37254 MGI:MGI:5610482 +100862402 Gm21711 MGI:MGI:5435066 +100862406 Gm21715 MGI:MGI:5435070 +100862408 LOC100862408 - +100862413 LOC100862413 - +100862414 LOC100862414 - +100862415 LOC100862415 - +100862416 LOC100862416 - +100862420 LOC100862420 - +100862425 LOC100862425 - +100862426 LOC100862426 - +100862431 LOC100862431 - +100862433 LOC100862433 - +100862434 LOC100862434 - +100862436 LOC100862436 - +100862441 LOC100862441 - +100862442 LOC100862442 - +100862444 LOC100862444 - +100862446 LOC100862446 - +100862449 LOC100862449 - +100862450 LOC100862450 - +100862454 LOC100862454 - +100862455 LOC100862455 - +100862456 LOC100862456 - +100862460 LOC100862460 - +100862464 LOC100862464 - +100862465 LOC100862465 - +100862466 LOC100862466 - +100862468 LOC100862468 - +100862470 LOC100862470 - +100862471 LOC100862471 - +100862473 LOC100862473 - +100862474 LOC100862474 - +100862493 Gm29698 MGI:MGI:5588857 +100862545 LOC100862545 - +100862598 Gm29699 MGI:MGI:5588858 +100873092 Gm15679 MGI:MGI:3783121|Ensembl:ENSMUSG00000089819 +100873094 Rubie MGI:MGI:5568573 +100885823 Mir3544 MGI:MGI:5562737|Ensembl:ENSMUSG00000105210|miRBase:MI0019179 +100885824 Mir299b MGI:MGI:5455177|Ensembl:ENSMUSG00000093291|miRBase:MI0019180 +100885825 Mir5615-1 MGI:MGI:5562727|Ensembl:ENSMUSG00000106347|miRBase:MI0019181 +100885826 Mir5615-2 MGI:MGI:5453144|Ensembl:ENSMUSG00000093498|miRBase:MI0019182 +100885827 Mir1231 MGI:MGI:5453497|Ensembl:ENSMUSG00000093515|miRBase:MI0019183 +100885828 Mir5616 MGI:MGI:5454968|Ensembl:ENSMUSG00000093403|miRBase:MI0019184 +100885829 Mir5617 MGI:MGI:5454969|Ensembl:ENSMUSG00000093408|miRBase:MI0019185 +100885830 Mir5618 MGI:MGI:5453462|Ensembl:ENSMUSG00000093615|miRBase:MI0019186 +100885831 Mir5619 MGI:MGI:5453643|Ensembl:ENSMUSG00000093690|miRBase:MI0019187 +100885832 Mir5620 MGI:MGI:5453349|Ensembl:ENSMUSG00000093599|miRBase:MI0019188 +100885833 Mir5621 MGI:MGI:5452341|Ensembl:ENSMUSG00000093539|miRBase:MI0019189 +100885834 Mir5622 MGI:MGI:5454198|Ensembl:ENSMUSG00000093746|miRBase:MI0019190 +100885835 Mir5623 MGI:MGI:5455845|Ensembl:ENSMUSG00000093757|miRBase:MI0019191 +100885836 Mir3073b MGI:MGI:5562738|Ensembl:ENSMUSG00000106228|miRBase:MI0019192 +100885837 Mir5624 MGI:MGI:5454852|Ensembl:ENSMUSG00000093480|miRBase:MI0019193 +100885838 Mir5625 MGI:MGI:5453707|Ensembl:ENSMUSG00000093710|miRBase:MI0019194 +100885839 Mir5626 MGI:MGI:5455367|Ensembl:ENSMUSG00000093763|miRBase:MI0019195 +100885840 Mir344h-1 MGI:MGI:5454202|Ensembl:ENSMUSG00000094173|miRBase:MI0019196 +100885841 Mir344h-2 MGI:MGI:5453086|Ensembl:ENSMUSG00000096189|miRBase:MI0019197 +100885842 Mir5627 MGI:MGI:5453461|Ensembl:ENSMUSG00000093618|miRBase:MI0019198 +100885843 Mir344i MGI:MGI:5455808|Ensembl:ENSMUSG00000095154|miRBase:MI0019317 +100885844 Mir5709 MGI:MGI:5451818|Ensembl:ENSMUSG00000093508|miRBase:MI0019318 +100885845 Mir5710 MGI:MGI:5452649|Ensembl:ENSMUSG00000093441|miRBase:MI0019319 +100909391 I-ag7 - +100913185 Gm29700 MGI:MGI:5588859 +100996932 Lincred2 MGI:MGI:5428673 +100996933 Lincred1 MGI:MGI:5428668 +101055498 AK155734 MGI:MGI:5433117 +101055627 Gm13866 MGI:MGI:3650317 +101055629 Gm29701 MGI:MGI:5588860 +101055632 Gm29582 MGI:MGI:5580288 +101055641 Gm29704 MGI:MGI:5588863 +101055648 Gm29705 MGI:MGI:5588864 +101055651 LOC101055651 - +101055656 LOC101055656 - +101055662 Gm29706 MGI:MGI:5588865 +101055663 LOC101055663 - +101055666 Gm29707 MGI:MGI:5588866 +101055669 Gm29708 MGI:MGI:5588867 +101055670 Heatr4 MGI:MGI:4937307 +101055671 Lipo2 MGI:MGI:3644466|Ensembl:ENSMUSG00000087303|Vega:OTTMUSG00000033077 +101055672 LOC101055672 - +101055673 LOC101055673 - +101055674 Gm29709 MGI:MGI:5588868 +101055676 LOC101055676 - +101055693 Gm29711 MGI:MGI:5588870 +101055696 LOC101055696 - +101055697 Gm29712 MGI:MGI:5588871 +101055702 Gm29713 MGI:MGI:5588872 +101055703 LOC101055703 - +101055706 Gm29714 MGI:MGI:5588873 +101055708 LOC101055708 - +101055709 Zfp264 MGI:MGI:2151059 +101055711 Gm29716 MGI:MGI:5588875 +101055712 Gm29717 MGI:MGI:5588876 +101055721 LOC101055721 - +101055723 Gm15113 MGI:MGI:3705832 +101055724 LOC101055724 - +101055725 Gm29718 MGI:MGI:5588877 +101055727 LOC101055727 - +101055731 Gm29719 MGI:MGI:5588878 +101055732 Gm15106 MGI:MGI:3705858 +101055735 Gm21815 MGI:MGI:5433979 +101055736 Gm38433 MGI:MGI:5621318 +101055737 LOC101055737 - +101055739 LOC101055739 - +101055741 Gm15112 MGI:MGI:3705878 +101055744 Gm29720 MGI:MGI:5588879 +101055745 Gm29721 MGI:MGI:5588880 +101055748 LOC101055748 - +101055749 LOC101055749 Ensembl:ENSMUSG00000059972 +101055750 Atp5k-ps1 MGI:MGI:107703 +101055751 LOC101055751 - +101055752 LOC101055752 - +101055754 LOC101055754 - +101055758 LOC101055758 - +101055759 Gm26592 MGI:MGI:5477086|Ensembl:ENSMUSG00000097535 +101055761 Gm15610 MGI:MGI:3783056 +101055763 Gm29722 MGI:MGI:5588881 +101055766 Gm21861 MGI:MGI:5434025 +101055769 Gm12596 MGI:MGI:3649247 +101055773 Gm29276 MGI:MGI:5579982 +101055774 Gm15090 MGI:MGI:3705844 +101055782 LOC101055782 - +101055786 Gm29605 MGI:MGI:5580311 +101055790 LOC101055790 - +101055792 LOC101055792 - +101055793 LOC101055793 - +101055797 LOC101055797 - +101055798 Gm29724 MGI:MGI:5588883 +101055802 LOC101055802 - +101055805 LOC101055805 - +101055806 Gm10378 MGI:MGI:3704430 +101055808 Gm29725 MGI:MGI:5588884 +101055810 LOC101055810 - +101055811 LOC101055811 - +101055813 Gm29726 MGI:MGI:5588885 +101055814 LOC101055814 - +101055836 LOC101055836 - +101055837 Gm38434 MGI:MGI:5621319 +101055839 Gm29728 MGI:MGI:5588887 +101055840 Gm29729 MGI:MGI:5588888 +101055841 Tmem167-ps1 MGI:MGI:5579307 +101055843 Plin2 - +101055845 Gm29730 MGI:MGI:5588889 +101055849 LOC101055849 - +101055850 Gm29731 MGI:MGI:5588890 +101055851 Gm29732 MGI:MGI:5588891 +101055854 Gm29733 MGI:MGI:5588892 +101055860 Gm29734 MGI:MGI:5588893 +101055862 Gm29735 MGI:MGI:5588894|Ensembl:ENSMUSG00000109655|Vega:OTTMUSG00000060162 +101055863 Gm11239 MGI:MGI:3702319|Ensembl:ENSMUSG00000095048|Vega:OTTMUSG00000000283 +101055864 LOC101055864 Ensembl:ENSMUSG00000109060|Vega:OTTMUSG00000059375 +101055867 Gm29736 MGI:MGI:5588895 +101055874 Gm29737 MGI:MGI:5588896 +101055875 Gm29610 MGI:MGI:5580316 +101055879 LOC101055879 - +101055888 LOC101055888 - +101055890 Gm29738 MGI:MGI:5588897 +101055891 Gm29739 MGI:MGI:5588898 +101055892 LOC101055892 - +101055894 LOC101055894 - +101055898 LOC101055898 - +101055899 LOC101055899 - +101055902 Gm29740 MGI:MGI:5588899 +101055903 Gm29741 MGI:MGI:5588900 +101055905 LOC101055905 - +101055907 LOC101055907 - +101055909 LOC101055909 - +101055911 Gm29742 MGI:MGI:5588901 +101055912 LOC101055912 Ensembl:ENSMUSG00000095710|Vega:OTTMUSG00000036519 +101055913 LOC101055913 - +101055915 LOC101055915 - +101055918 Gm29743 MGI:MGI:5588902 +101055923 LOC101055923 - +101055931 Gm29745 MGI:MGI:5588904 +101055933 Gm29746 MGI:MGI:5588905 +101055938 Gm29747 MGI:MGI:5588906 +101055939 LOC101055939 Ensembl:ENSMUSG00000106350|Vega:OTTMUSG00000054827 +101055941 Gm29748 MGI:MGI:5588907 +101055944 LOC101055944 - +101055947 Gm29316 MGI:MGI:5580022 +101055951 LOC101055951 - +101055953 LOC101055953 - +101055956 Gm29753 MGI:MGI:5588912 +101055958 Gm28216 MGI:MGI:5578922 +101055959 LOC101055959 - +101055960 LOC101055960 - +101055965 Gm28092 MGI:MGI:5578798 +101055968 LOC101055968 - +101055972 Gm29754 MGI:MGI:5588913 +101055974 Gm29755 MGI:MGI:5588914 +101055979 LOC101055979 - +101055980 LOC101055980 - +101055983 Gm14569 MGI:MGI:3705243|Ensembl:ENSMUSG00000091556|Vega:OTTMUSG00000017248 +101055987 Gm29758 MGI:MGI:5588917 +101055991 Gm13772 MGI:MGI:3650155 +101055992 LOC101055992 - +101055993 Gm29138 MGI:MGI:5579844 +101055995 LOC101055995 - +101055996 Gm29759 MGI:MGI:5588918 +101056001 LOC101056001 Ensembl:ENSMUSG00000084890 +101056006 Gm29761 MGI:MGI:5588920 +101056009 Gm29762 MGI:MGI:5588921 +101056011 LOC101056011 - +101056012 Gm29263 MGI:MGI:5579969 +101056014 LOC101056014 - +101056015 LOC101056015 - +101056017 Gm28802 MGI:MGI:5579508 +101056018 Gm28859 MGI:MGI:5579565 +101056020 Gm29396 MGI:MGI:5580102 +101056023 Gm29763 MGI:MGI:5588922 +101056029 LOC101056029 - +101056032 LOC101056032 - +101056033 Gm28408 MGI:MGI:5579114 +101056035 LOC101056035 - +101056040 Gm29764 MGI:MGI:5588923 +101056044 Gm27219 MGI:MGI:5521062 +101056046 LOC101056046 - +101056047 Gm28455 MGI:MGI:5579161 +101056048 Gm28517 MGI:MGI:5579223 +101056051 Gm28384 MGI:MGI:5579090 +101056052 Gm29767 MGI:MGI:5588926 +101056055 Gm29769 MGI:MGI:5588928 +101056056 LOC101056056 - +101056057 Gm26853 MGI:MGI:5477347 +101056060 Gm28480 MGI:MGI:5579186 +101056061 Gm29770 MGI:MGI:5588929 +101056063 Gm29656 MGI:MGI:5580362 +101056065 Gm29771 MGI:MGI:5588930 +101056070 Gm29772 MGI:MGI:5588931 +101056071 LOC101056071 - +101056072 Gm29773 MGI:MGI:5588932 +101056073 LOC101056073 Ensembl:ENSMUSG00000078503|Vega:OTTMUSG00000011027 +101056075 LOC101056075 - +101056081 Gm29774 MGI:MGI:5588933 +101056083 Gm29029 MGI:MGI:5579735 +101056084 Gm29776 MGI:MGI:5588935 +101056088 Gm28649 MGI:MGI:5579355 +101056091 Gm29024 MGI:MGI:5579730 +101056092 Gm29777 MGI:MGI:5588936 +101056093 LOC101056093 - +101056094 Gm21811 MGI:MGI:5433975 +101056096 Gm21806 MGI:MGI:5433970 +101056097 Gm29778 MGI:MGI:5588937 +101056099 Gm21799 MGI:MGI:5433963 +101056100 LOC101056100 - +101056102 Gm29779 MGI:MGI:5588938 +101056106 LOC101056106 - +101056109 Gm29564 MGI:MGI:5580270 +101056111 Gm29411 MGI:MGI:5580117 +101056113 Gm29781 MGI:MGI:5588940 +101056115 LOC101056115 Ensembl:ENSMUSG00000091594|Vega:OTTMUSG00000035834 +101056116 Gm21760 MGI:MGI:5433924 +101056118 Gm29782 MGI:MGI:5588941 +101056119 Gm29783 MGI:MGI:5588942 +101056120 LOC101056120 - +101056121 Gm21835 MGI:MGI:5433999 +101056129 Gm29784 MGI:MGI:5588943 +101056130 Gm29785 MGI:MGI:5588944 +101056131 LOC101056131 - +101056136 Gm17026 MGI:MGI:4937853|Ensembl:ENSMUSG00000092152|Vega:OTTMUSG00000036344 +101056138 Gm20619 MGI:MGI:5313066|Ensembl:ENSMUSG00000093482 +101056142 Gm29787 MGI:MGI:5588946 +101056144 LOC101056144 - +101056148 Gm29788 MGI:MGI:5588947 +101056149 Gm15908 MGI:MGI:3801931|Ensembl:ENSMUSG00000086786 +101056159 LOC101056159 Ensembl:ENSMUSG00000096446|Vega:OTTMUSG00000036366 +101056161 Gm21909 MGI:MGI:5434073 +101056162 Gm6166 MGI:MGI:3645893 +101056163 LOC101056163 - +101056166 Gm29645 MGI:MGI:5580351 +101056169 LOC101056169 - +101056171 Gm29789 MGI:MGI:5588948 +101056173 Gm21778 MGI:MGI:5433942 +101056174 Gm28312 MGI:MGI:5579018 +101056177 Gm29790 MGI:MGI:5588949 +101056178 Gm29791 MGI:MGI:5588950 +101056181 Gm29792 MGI:MGI:5588951 +101056185 Gm13301 MGI:MGI:3707230 +101056188 Gm29793 MGI:MGI:5588952 +101056194 Gm28998 MGI:MGI:5579704|Ensembl:ENSMUSG00000100939|Vega:OTTMUSG00000045869 +101056195 Gm28461 MGI:MGI:5579167 +101056198 Gm29794 MGI:MGI:5588953 +101056200 Gm29795 MGI:MGI:5588954 +101056201 Gm28397 MGI:MGI:5579103 +101056204 Gm29796 MGI:MGI:5588955 +101056205 Gm29797 MGI:MGI:5588956|Ensembl:ENSMUSG00000108976|Vega:OTTMUSG00000060041 +101056208 Gm29798 MGI:MGI:5588957 +101056210 Gm28576 MGI:MGI:5579282|Ensembl:ENSMUSG00000100645|Vega:OTTMUSG00000046113 +101056211 Gm29799 MGI:MGI:5588958 +101056219 LOC101056219 - +101056221 Crry-ps MGI:MGI:88514 +101056222 Gm28574 MGI:MGI:5579280 +101056223 Gm29800 MGI:MGI:5588959 +101056225 Gm29801 MGI:MGI:5588960 +101056229 Gm29802 MGI:MGI:5588961 +101056230 Gm28682 MGI:MGI:5579388 +101056231 Gm29803 MGI:MGI:5588962 +101056232 Gm29804 MGI:MGI:5588963 +101056233 LOC101056233 - +101056236 Gm29805 MGI:MGI:5588964 +101056237 Gm29806 MGI:MGI:5588965 +101056238 Gm29807 MGI:MGI:5588966 +101056240 LOC101056240 - +101056241 Gm29808 MGI:MGI:5588967 +101056245 Gm29809 MGI:MGI:5588968 +101056250 Gm16026 MGI:MGI:3783243 +101056256 LOC101056256 - +101056270 Gm29810 MGI:MGI:5588969 +101056296 LOC101056296 - +101056300 LOC101056300 - +101056302 LOC101056302 - +101056303 LOC101056303 - +101056304 LOC101056304 - +101056305 LOC101056305 - +101056306 LOC101056306 - +101056307 Gm28851 MGI:MGI:5579557 +101056308 LOC101056308 - +101056408 Gm15816 MGI:MGI:3802114 +101101691 Hm629797 MGI:MGI:5440479 +101154638 Gm5121 MGI:MGI:3647258 +101154646 4930401B11Rik MGI:MGI:1921073 +101180908 LOC101180908 - +101202683 Dreh MGI:MGI:5446626 +101202684 Uchl1os MGI:MGI:5446771|Ensembl:ENSMUSG00000087601 +101243624 Gm29811 MGI:MGI:5588970|Ensembl:ENSMUSG00000106230 +101243625 Gm29812 MGI:MGI:5588971 +101447999 Mirc35hg MGI:MGI:5475487 +101488143 Hbb-bt MGI:MGI:5474850|Ensembl:ENSMUSG00000073940|Vega:OTTMUSG00000019042 +101488212 Evi2 MGI:MGI:5439444|Ensembl:ENSMUSG00000070354 +101669761 Gm15694 MGI:MGI:3783135 +101696218 Gm28552 MGI:MGI:5579258 +101954205 Gm29813 MGI:MGI:5588972 +102216269 Gm38436 MGI:MGI:5621321 +102216271 Gm29814 MGI:MGI:5588973 +102216272 Ak6 MGI:MGI:5510732|Ensembl:ENSMUSG00000078941|Vega:OTTMUSG00000045171 +102238433 Gm28042 MGI:MGI:5547778|Ensembl:ENSMUSG00000033852|Vega:OTTMUSG00000044912 +102238517 LOC102238517 - +102238518 LOC102238518 - +102238519 Gm29815 MGI:MGI:5588974 +102238520 LOC102238520 - +102238521 Gm29816 MGI:MGI:5588975 +102238522 Gm29817 MGI:MGI:5588976 +102238523 LOC102238523 - +102238524 Gm29818 MGI:MGI:5588977 +102238526 LOC102238526 - +102238527 Gm29819 MGI:MGI:5588978 +102308570 Lbhd1 MGI:MGI:5516029|Ensembl:ENSMUSG00000096740|Vega:OTTMUSG00000045560 +102392594 LOC102392594 - +102443350 Xndc1 MGI:MGI:5546359|Ensembl:ENSMUSG00000070425|Ensembl:ENSMUSG00000099481|Vega:OTTMUSG00000045817|Vega:OTTMUSG00000045818 +102443351 Xntrpc MGI:MGI:5546370|Ensembl:ENSMUSG00000070425|Vega:OTTMUSG00000045818 +102465114 Gm38437 MGI:MGI:5621322|Ensembl:ENSMUSG00000105118|miRBase:MI0020958 +102465148 Mir6239 MGI:MGI:5531407|Ensembl:ENSMUSG00000098648|miRBase:MI0021586 +102465149 Mir6241 MGI:MGI:5530684|Ensembl:ENSMUSG00000098612|miRBase:MI0021588 +102465150 Mir6244 MGI:MGI:5530750|Ensembl:ENSMUSG00000099311|miRBase:MI0021591 +102465169 Mir195b MGI:MGI:5530873|Ensembl:ENSMUSG00000098437|miRBase:MI0021861 +102465170 Mir133c MGI:MGI:5531247|Ensembl:ENSMUSG00000098539|miRBase:MI0021863 +102465171 Mir6336 MGI:MGI:5530966|Ensembl:ENSMUSG00000098660|miRBase:MI0021864 +102465172 Mir6338 MGI:MGI:5531060|Ensembl:ENSMUSG00000098658|miRBase:MI0021866 +102465173 Mir6340 MGI:MGI:5531291|Ensembl:ENSMUSG00000098588|miRBase:MI0021868 +102465174 Mir6342 MGI:MGI:5530650|Ensembl:ENSMUSG00000099257|miRBase:MI0021870 +102465175 Mir6343 MGI:MGI:5530686|Ensembl:ENSMUSG00000098611|miRBase:MI0021871 +102465176 Mir6346 MGI:MGI:5531211|Ensembl:ENSMUSG00000098273|miRBase:MI0021874 +102465177 Mir6347 MGI:MGI:5531245|Ensembl:ENSMUSG00000098379|miRBase:MI0021875 +102465178 Mir6348 MGI:MGI:5530794|Ensembl:ENSMUSG00000098407|miRBase:MI0021876 +102465179 Mir6351 MGI:MGI:5531318|Ensembl:ENSMUSG00000098504|miRBase:MI0021879 +102465180 Mir6352 MGI:MGI:5530863|Ensembl:ENSMUSG00000099141|miRBase:MI0021880 +102465181 Mir6353 MGI:MGI:5530773|Ensembl:ENSMUSG00000098851|miRBase:MI0021881 +102465182 Mir6355 MGI:MGI:5530855|Ensembl:ENSMUSG00000098287|miRBase:MI0021883 +102465183 Mir6356 MGI:MGI:5530843|Ensembl:ENSMUSG00000099300|miRBase:MI0021884 +102465184 Mir6358 MGI:MGI:5531212|Ensembl:ENSMUSG00000098276|miRBase:MI0021886 +102465185 Mir6360 MGI:MGI:5530678|Ensembl:ENSMUSG00000098607|miRBase:MI0021888 +102465186 Mir6361 MGI:MGI:5530994|Ensembl:ENSMUSG00000098252|miRBase:MI0021889 +102465187 Mir145b MGI:MGI:5531026|Ensembl:ENSMUSG00000098366|miRBase:MI0021890 +102465188 Mir6364 MGI:MGI:5530709|Ensembl:ENSMUSG00000098675|miRBase:MI0021893 +102465189 Mir6366 MGI:MGI:5531102|Ensembl:ENSMUSG00000099293|miRBase:MI0021895 +102465190 Mir6367 MGI:MGI:5530849|Ensembl:ENSMUSG00000099308|miRBase:MI0021896 +102465191 Mir6369 MGI:MGI:5530997|Ensembl:ENSMUSG00000098258|miRBase:MI0021898 +102465192 Mir6370 MGI:MGI:5530862|Ensembl:ENSMUSG00000099149|miRBase:MI0021899 +102465193 Mir6371 MGI:MGI:5530758|Ensembl:ENSMUSG00000099221|miRBase:MI0021900 +102465194 Mir6374 MGI:MGI:5530674|Ensembl:ENSMUSG00000099045|miRBase:MI0021903 +102465195 Mir6375 MGI:MGI:5562769|Ensembl:ENSMUSG00000105002|miRBase:MI0021904 +102465196 Mir6376 MGI:MGI:5531160|Ensembl:ENSMUSG00000099095|miRBase:MI0021905 +102465197 Mir6377 MGI:MGI:5530798|Ensembl:ENSMUSG00000098401|miRBase:MI0021907 +102465198 Mir7j MGI:MGI:5531098|Ensembl:ENSMUSG00000099169|miRBase:MI0021908 +102465199 Mir6379 MGI:MGI:5531112|Ensembl:ENSMUSG00000098417|miRBase:MI0021910 +102465200 Mir6381 MGI:MGI:5531345|Ensembl:ENSMUSG00000098871|miRBase:MI0021912 +102465201 Mir6383 MGI:MGI:5531071|Ensembl:ENSMUSG00000098493|miRBase:MI0021914 +102465202 Mir6384 MGI:MGI:5562785|Ensembl:ENSMUSG00000105738|miRBase:MI0021915 +102465203 Mir6386 MGI:MGI:5531224|Ensembl:ENSMUSG00000098766|miRBase:MI0021918 +102465204 Mir6387 MGI:MGI:5530663|Ensembl:ENSMUSG00000098480|miRBase:MI0021919 +102465205 Mir6388 MGI:MGI:5531307|Ensembl:ENSMUSG00000098336|miRBase:MI0021920 +102465206 Mir378c MGI:MGI:5531312|Ensembl:ENSMUSG00000099036|miRBase:MI0021923 +102465207 Mir6390 MGI:MGI:5530944|Ensembl:ENSMUSG00000098780|miRBase:MI0021924 +102465208 Mir6391 MGI:MGI:5531296|Ensembl:ENSMUSG00000098433|miRBase:MI0021925 +102465209 Mir6393 MGI:MGI:5530806|Ensembl:ENSMUSG00000098938|miRBase:MI0021927 +102465210 Mir6394 MGI:MGI:5531311|Ensembl:ENSMUSG00000099030|miRBase:MI0021928 +102465211 Mir6395 MGI:MGI:5530943|Ensembl:ENSMUSG00000098785|miRBase:MI0021930 +102465212 Mir21c MGI:MGI:5531395|Ensembl:ENSMUSG00000099326|miRBase:MI0021932 +102465213 Mir6397 MGI:MGI:5531386|Ensembl:ENSMUSG00000098980|miRBase:MI0021933 +102465214 Mir6398 MGI:MGI:5531039|Ensembl:ENSMUSG00000099005|miRBase:MI0021934 +102465215 Mir6401 MGI:MGI:5530824|Ensembl:ENSMUSG00000098619|miRBase:MI0021937 +102465216 Mir6403 MGI:MGI:5531374|Ensembl:ENSMUSG00000099289|miRBase:MI0021939 +102465217 Mir6404 MGI:MGI:5531396|Ensembl:ENSMUSG00000099321|miRBase:MI0021940 +102465218 Mir496b MGI:MGI:5531410|Ensembl:ENSMUSG00000098718|miRBase:MI0021942 +102465219 Mir6406 MGI:MGI:5531363|Ensembl:ENSMUSG00000099174|miRBase:MI0021943 +102465220 Mir6407 MGI:MGI:5531214|Ensembl:ENSMUSG00000098730|miRBase:MI0021944 +102465221 Mir6410 MGI:MGI:5531298|Ensembl:ENSMUSG00000098932|miRBase:MI0021947 +102465222 Mir6411 MGI:MGI:5531149|Ensembl:ENSMUSG00000099264|miRBase:MI0021948 +102465223 Mir6412 MGI:MGI:5530746|Ensembl:ENSMUSG00000098522|miRBase:MI0021949 +102465224 Mir378d MGI:MGI:5531032|Ensembl:ENSMUSG00000098756|miRBase:MI0021951 +102465225 Mir6414 MGI:MGI:5530900|Ensembl:ENSMUSG00000098264|miRBase:MI0021952 +102465226 Mir6416 MGI:MGI:5531128|Ensembl:ENSMUSG00000098910|miRBase:MI0021954 +102465227 Mir6418 MGI:MGI:5531011|Ensembl:ENSMUSG00000098597|miRBase:MI0021956 +102465228 Mir6420 MGI:MGI:5531389|Ensembl:ENSMUSG00000098984|miRBase:MI0021958 +102465229 Mir873b MGI:MGI:5562760|Ensembl:ENSMUSG00000106425|miRBase:MI0021959 +102465230 Mir6481 MGI:MGI:5531126|Ensembl:ENSMUSG00000098918|miRBase:MI0022051 +102465258 Mir6516 MGI:MGI:5562736|Ensembl:ENSMUSG00000104740|miRBase:MI0022266 +102465309 Mir7k MGI:MGI:5531196|Ensembl:ENSMUSG00000098687|miRBase:MI0022352 +102465310 Mir6539 MGI:MGI:5530846|Ensembl:ENSMUSG00000098866|miRBase:MI0022355 +102465311 Mir6541 MGI:MGI:5530693|Ensembl:ENSMUSG00000098858|miRBase:MI0022358 +102465540 Mir6897 MGI:MGI:5531034|Ensembl:ENSMUSG00000098752|miRBase:MI0022744 +102465541 Mir6898 MGI:MGI:5531198|Ensembl:ENSMUSG00000098680|miRBase:MI0022745 +102465542 Mir6900 MGI:MGI:5531090|Ensembl:ENSMUSG00000098288|miRBase:MI0022747 +102465543 Mir6901 MGI:MGI:5531114|Ensembl:ENSMUSG00000098997|miRBase:MI0022748 +102465544 Mir6902 MGI:MGI:5562723|Ensembl:ENSMUSG00000106302|miRBase:MI0022749 +102465545 Mir6905 MGI:MGI:5531261|Ensembl:ENSMUSG00000099181|miRBase:MI0022752 +102465546 Mir6906 MGI:MGI:5562725|Ensembl:ENSMUSG00000105468|miRBase:MI0022753 +102465547 Mir6907 MGI:MGI:5530733|Ensembl:ENSMUSG00000098376|miRBase:MI0022754 +102465548 Mir6909 MGI:MGI:5531109|Ensembl:ENSMUSG00000098414|miRBase:MI0022756 +102465549 Mir6910 MGI:MGI:5531145|Ensembl:ENSMUSG00000098562|miRBase:MI0022757 +102465550 Mir6912 MGI:MGI:5531372|Ensembl:ENSMUSG00000099283|miRBase:MI0022759 +102465551 Mir6914 MGI:MGI:5530908|Ensembl:ENSMUSG00000098701|miRBase:MI0022761 +102465552 Mir6916 MGI:MGI:5531103|Ensembl:ENSMUSG00000099292|miRBase:MI0022763 +102465553 Mir6917 MGI:MGI:5531015|Ensembl:ENSMUSG00000098592|miRBase:MI0022764 +102465554 Mir6920 MGI:MGI:5562731|Ensembl:ENSMUSG00000105908|miRBase:MI0022767 +102465555 Mir6921 MGI:MGI:5530734|Ensembl:ENSMUSG00000098547|miRBase:MI0022768 +102465556 Mir6922 MGI:MGI:5530651|Ensembl:ENSMUSG00000099259|miRBase:MI0022769 +102465557 Mir6925 MGI:MGI:5562733|Ensembl:ENSMUSG00000105932|miRBase:MI0022772 +102465558 Mir6926 MGI:MGI:5531331|Ensembl:ENSMUSG00000098317|miRBase:MI0022773 +102465559 Mir6927 MGI:MGI:5531044|Ensembl:ENSMUSG00000098881|miRBase:MI0022774 +102465560 Mir6929 MGI:MGI:5530680|Ensembl:ENSMUSG00000098600|miRBase:MI0022776 +102465561 Mir6930 MGI:MGI:5530818|Ensembl:ENSMUSG00000098774|miRBase:MI0022777 +102465562 Mir6932 MGI:MGI:5531073|Ensembl:ENSMUSG00000098497|miRBase:MI0022779 +102465563 Mir6934 MGI:MGI:5530905|Ensembl:ENSMUSG00000098704|miRBase:MI0022781 +102465564 Mir6935 MGI:MGI:5530726|Ensembl:ENSMUSG00000098955|miRBase:MI0022782 +102465565 Mir6936 MGI:MGI:5530956|Ensembl:ENSMUSG00000098282|miRBase:MI0022783 +102465566 Mir6939 MGI:MGI:5530880|Ensembl:ENSMUSG00000098380|miRBase:MI0022786 +102465567 Mir6941 MGI:MGI:5531305|Ensembl:ENSMUSG00000098338|miRBase:MI0022788 +102465568 Mir6942 MGI:MGI:5530669|Ensembl:ENSMUSG00000098790|miRBase:MI0022789 +102465569 Mir6944 MGI:MGI:5531092|Ensembl:ENSMUSG00000098341|miRBase:MI0022791 +102465570 Mir6945 MGI:MGI:5531161|Ensembl:ENSMUSG00000099096|miRBase:MI0022792 +102465571 Mir6946 MGI:MGI:5531181|Ensembl:ENSMUSG00000098602|miRBase:MI0022793 +102465572 Mir6949 MGI:MGI:5531079|Ensembl:ENSMUSG00000098961|miRBase:MI0022796 +102465573 Mir6950 MGI:MGI:5530968|Ensembl:ENSMUSG00000098666|miRBase:MI0022797 +102465574 Mir6951 MGI:MGI:5531147|Ensembl:ENSMUSG00000099110|miRBase:MI0022798 +102465575 Mir6953 MGI:MGI:5531120|Ensembl:ENSMUSG00000098625|miRBase:MI0022800 +102465576 Mir6954 MGI:MGI:5531152|Ensembl:ENSMUSG00000099260|miRBase:MI0022801 +102465577 Mir6956 MGI:MGI:5531262|Ensembl:ENSMUSG00000099180|miRBase:MI0022803 +102465578 Mir6958 MGI:MGI:5530963|Ensembl:ENSMUSG00000098663|miRBase:MI0022805 +102465579 Mir6960 MGI:MGI:5531002|Ensembl:ENSMUSG00000098698|miRBase:MI0022807 +102465580 Mir6961 MGI:MGI:5530749|Ensembl:ENSMUSG00000098527|miRBase:MI0022808 +102465581 Mir6964 MGI:MGI:5562746|Ensembl:ENSMUSG00000105138|miRBase:MI0022811 +102465582 Mir6965 MGI:MGI:5530706|Ensembl:ENSMUSG00000099123|miRBase:MI0022812 +102465583 Mir3547 MGI:MGI:5452187|Ensembl:ENSMUSG00000093202|miRBase:MI0022813 +102465584 Mir6968 MGI:MGI:5531048|Ensembl:ENSMUSG00000098510|miRBase:MI0022816 +102465585 Mir6969 MGI:MGI:5530687|Ensembl:ENSMUSG00000099152|miRBase:MI0022817 +102465586 Mir6970 MGI:MGI:5530971|Ensembl:ENSMUSG00000098460|miRBase:MI0022818 +102465587 Mir6972 MGI:MGI:5531192|Ensembl:ENSMUSG00000098445|miRBase:MI0022820 +102465588 Mir6973a MGI:MGI:5531349|Ensembl:ENSMUSG00000098291|miRBase:MI0022821 +102465589 Mir6975 MGI:MGI:5531075|Ensembl:ENSMUSG00000098499|miRBase:MI0022823 +102465590 Mir6977 MGI:MGI:5531304|Ensembl:ENSMUSG00000098339|miRBase:MI0022825 +102465591 Mir6978 MGI:MGI:5531240|Ensembl:ENSMUSG00000099066|miRBase:MI0022826 +102465592 Mir6979 MGI:MGI:5530906|Ensembl:ENSMUSG00000098706|miRBase:MI0022827 +102465593 Mir6982 MGI:MGI:5531272|Ensembl:ENSMUSG00000098475|miRBase:MI0022830 +102465594 Mir6984 MGI:MGI:5531153|Ensembl:ENSMUSG00000099261|miRBase:MI0022832 +102465595 Mir6985 MGI:MGI:5531101|Ensembl:ENSMUSG00000099290|miRBase:MI0022833 +102465596 Mir6987 MGI:MGI:5531273|Ensembl:ENSMUSG00000098568|miRBase:MI0022835 +102465597 Mir6988 MGI:MGI:5530975|Ensembl:ENSMUSG00000098928|miRBase:MI0022836 +102465598 Mir6989 MGI:MGI:5531267|Ensembl:ENSMUSG00000099230|miRBase:MI0022837 +102465599 Mir6992 MGI:MGI:5531288|Ensembl:ENSMUSG00000098844|miRBase:MI0022840 +102465600 Mir6993 MGI:MGI:5531024|Ensembl:ENSMUSG00000098363|miRBase:MI0022841 +102465601 Mir6994 MGI:MGI:5562752|Ensembl:ENSMUSG00000104979|miRBase:MI0022842 +102465602 Mir6996 MGI:MGI:5530913|Ensembl:ENSMUSG00000098548|miRBase:MI0022844 +102465603 Mir6997 MGI:MGI:5530692|Ensembl:ENSMUSG00000098453|miRBase:MI0022845 +102465604 Mir6999 MGI:MGI:5531055|Ensembl:ENSMUSG00000098651|miRBase:MI0022847 +102465605 Mir7001 MGI:MGI:5531268|Ensembl:ENSMUSG00000099238|miRBase:MI0022849 +102465606 Mir6973b MGI:MGI:5531197|Ensembl:ENSMUSG00000098686|miRBase:MI0022851 +102465607 Mir7003 MGI:MGI:5530722|Ensembl:ENSMUSG00000099091|miRBase:MI0022852 +102465608 Mir7006 MGI:MGI:5530780|Ensembl:ENSMUSG00000098824|miRBase:MI0022855 +102465609 Mir7007 MGI:MGI:5531279|Ensembl:ENSMUSG00000099105|miRBase:MI0022856 +102465610 Mir7008 MGI:MGI:5531134|Ensembl:ENSMUSG00000098890|miRBase:MI0022857 +102465611 Mir7011 MGI:MGI:5531059|Ensembl:ENSMUSG00000098655|miRBase:MI0022860 +102465612 Mir7012 MGI:MGI:5530752|Ensembl:ENSMUSG00000099199|miRBase:MI0022861 +102465613 Mir7013 MGI:MGI:5530870|Ensembl:ENSMUSG00000099033|miRBase:MI0022862 +102465614 Mir7015 MGI:MGI:5562762|Ensembl:ENSMUSG00000106436|miRBase:MI0022864 +102465615 Mir7016 MGI:MGI:5531376|Ensembl:ENSMUSG00000098422|miRBase:MI0022865 +102465616 Mir7018 MGI:MGI:5530988|Ensembl:ENSMUSG00000099134|miRBase:MI0022867 +102465617 Mir7020 MGI:MGI:5531141|Ensembl:ENSMUSG00000098569|miRBase:MI0022869 +102465618 Mir7021 MGI:MGI:5562764|Ensembl:ENSMUSG00000106597|miRBase:MI0022870 +102465619 Mir7022 MGI:MGI:5530673|Ensembl:ENSMUSG00000099043|miRBase:MI0022871 +102465620 Mir7025 MGI:MGI:5531242|Ensembl:ENSMUSG00000099060|miRBase:MI0022874 +102465621 Mir7027 MGI:MGI:5531213|Ensembl:ENSMUSG00000098731|miRBase:MI0022876 +102465622 Mir7028 MGI:MGI:5531056|Ensembl:ENSMUSG00000098656|miRBase:MI0022877 +102465623 Mir7030 MGI:MGI:5530649|Ensembl:ENSMUSG00000099254|miRBase:MI0022879 +102465624 Mir7031 MGI:MGI:5531241|Ensembl:ENSMUSG00000099063|miRBase:MI0022880 +102465625 Mir7032 MGI:MGI:5530691|Ensembl:ENSMUSG00000098454|miRBase:MI0022881 +102465626 Mir7035 MGI:MGI:5531043|Ensembl:ENSMUSG00000099003|miRBase:MI0022884 +102465627 Mir7036 MGI:MGI:5531355|Ensembl:ENSMUSG00000098624|miRBase:MI0022885 +102465628 Mir7037 MGI:MGI:5530829|Ensembl:ENSMUSG00000098574|miRBase:MI0022886 +102465629 Mir7039 MGI:MGI:5531206|Ensembl:ENSMUSG00000098822|miRBase:MI0022888 +102465630 Mir7040 MGI:MGI:5530871|Ensembl:ENSMUSG00000099035|miRBase:MI0022889 +102465631 Mir7042 MGI:MGI:5562771|Ensembl:ENSMUSG00000106581|miRBase:MI0022891 +102465632 Mir7044 MGI:MGI:5530736|Ensembl:ENSMUSG00000098583|miRBase:MI0022893 +102465633 Mir7046 MGI:MGI:5530851|Ensembl:ENSMUSG00000098802|miRBase:MI0022895 +102465634 Mir7047 MGI:MGI:5530652|Ensembl:ENSMUSG00000099258|miRBase:MI0022896 +102465635 Mir7050 MGI:MGI:5530960|Ensembl:ENSMUSG00000098783|miRBase:MI0022899 +102465636 Mir7051 MGI:MGI:5531067|Ensembl:ENSMUSG00000099210|miRBase:MI0022900 +102465637 Mir7052 MGI:MGI:5530965|Ensembl:ENSMUSG00000098661|miRBase:MI0022901 +102465638 Mir7055 MGI:MGI:5562777|Ensembl:ENSMUSG00000106470|miRBase:MI0022904 +102465639 Mir7056 MGI:MGI:5531078|Ensembl:ENSMUSG00000098960|miRBase:MI0022905 +102465640 Mir7057 MGI:MGI:5530932|Ensembl:ENSMUSG00000098353|miRBase:MI0022906 +102465641 Mir7059 MGI:MGI:5530916|Ensembl:ENSMUSG00000098540|miRBase:MI0022908 +102465642 Mir7060 MGI:MGI:5530897|Ensembl:ENSMUSG00000098267|miRBase:MI0022909 +102465643 Mir7062 MGI:MGI:5530721|Ensembl:ENSMUSG00000099092|miRBase:MI0022911 +102465644 Mir7064 MGI:MGI:5531014|Ensembl:ENSMUSG00000098593|miRBase:MI0022913 +102465645 Mir7065 MGI:MGI:5531253|Ensembl:ENSMUSG00000098532|miRBase:MI0022914 +102465646 Mir7066 MGI:MGI:5530672|Ensembl:ENSMUSG00000099042|miRBase:MI0022915 +102465647 Mir7068 MGI:MGI:5530952|Ensembl:ENSMUSG00000099079|miRBase:MI0022918 +102465648 Mir7070 MGI:MGI:5530947|Ensembl:ENSMUSG00000099076|miRBase:MI0022920 +102465649 Mir7071 MGI:MGI:5531005|Ensembl:ENSMUSG00000099080|miRBase:MI0022921 +102465650 Mir7073 MGI:MGI:5562782|Ensembl:ENSMUSG00000106145|miRBase:MI0022923 +102465651 Mir7074 MGI:MGI:5530985|Ensembl:ENSMUSG00000099131|miRBase:MI0022924 +102465652 Mir7075 MGI:MGI:5531203|Ensembl:ENSMUSG00000098671|miRBase:MI0022925 +102465653 Mir7078 MGI:MGI:5530768|Ensembl:ENSMUSG00000098483|miRBase:MI0022928 +102465654 Mir7079 MGI:MGI:5530660|Ensembl:ENSMUSG00000098550|miRBase:MI0022929 +102465655 Mir7080 MGI:MGI:5531293|Ensembl:ENSMUSG00000098582|miRBase:MI0022930 +102465656 Mir7082 MGI:MGI:5531315|Ensembl:ENSMUSG00000098907|miRBase:MI0022932 +102465657 Mir7083 MGI:MGI:5531270|Ensembl:ENSMUSG00000098473|miRBase:MI0022933 +102465658 Mir7085 MGI:MGI:5530805|Ensembl:ENSMUSG00000099309|miRBase:MI0022935 +102465659 Mir7087 MGI:MGI:5530655|Ensembl:ENSMUSG00000098327|miRBase:MI0022937 +102465660 Mir7089 MGI:MGI:5530800|Ensembl:ENSMUSG00000098490|miRBase:MI0022939 +102465661 Mir7090 MGI:MGI:5562784|Ensembl:ENSMUSG00000106193|miRBase:MI0022940 +102465662 Mir7092 MGI:MGI:5562787|Ensembl:ENSMUSG00000106409|miRBase:MI0022942 +102465663 Mir7094-1 MGI:MGI:5562739|Ensembl:ENSMUSG00000105438|miRBase:MI0022944 +102465664 Mir7094-2 MGI:MGI:5530890|Ensembl:ENSMUSG00000098357|miRBase:MI0022945 +102465670 Mir7115 MGI:MGI:5531284|Ensembl:ENSMUSG00000099109|miRBase:MI0022966 +102465671 Mir7116 MGI:MGI:5562735|Ensembl:ENSMUSG00000104854|miRBase:MI0022967 +102465672 Mir7118 MGI:MGI:5562743|Ensembl:ENSMUSG00000106328|miRBase:MI0022969 +102465673 Mir7119 MGI:MGI:5530942|Ensembl:ENSMUSG00000098831|miRBase:MI0022970 +102465697 Mir7210 MGI:MGI:5562740|Ensembl:ENSMUSG00000105723|miRBase:MI0023705 +102465698 Mir7212 MGI:MGI:5531409|Ensembl:ENSMUSG00000098719|miRBase:MI0023707 +102465699 Mir7213 MGI:MGI:5530759|Ensembl:ENSMUSG00000099222|miRBase:MI0023708 +102465700 Mir7214 MGI:MGI:5562747|Ensembl:ENSMUSG00000105142|miRBase:MI0023709 +102465701 Mir7217 MGI:MGI:5562748|Ensembl:ENSMUSG00000106578|miRBase:MI0023712 +102465702 Mir7219 MGI:MGI:5530995|Ensembl:ENSMUSG00000098253|miRBase:MI0023714 +102465703 Mir7220 MGI:MGI:5530711|Ensembl:ENSMUSG00000098247|miRBase:MI0023715 +102465704 Mir7222 MGI:MGI:5530795|Ensembl:ENSMUSG00000098406|miRBase:MI0023717 +102465705 Mir7223 MGI:MGI:5531391|Ensembl:ENSMUSG00000098989|miRBase:MI0023718 +102465706 Mir7224 MGI:MGI:5531353|Ensembl:ENSMUSG00000098299|miRBase:MI0023719 +102465707 Mir7227 MGI:MGI:5562763|Ensembl:ENSMUSG00000104566|miRBase:MI0023722 +102465708 Mir7228 MGI:MGI:5562767|Ensembl:ENSMUSG00000106323|miRBase:MI0023723 +102465709 Mir7229 MGI:MGI:5562765|Ensembl:ENSMUSG00000105778|miRBase:MI0023724 +102465710 Mir7231 MGI:MGI:5562772|Ensembl:ENSMUSG00000106580|miRBase:MI0023726 +102465711 Mir7232 MGI:MGI:5562768|Ensembl:ENSMUSG00000106154|miRBase:MI0023727 +102465712 Mir7234 MGI:MGI:5562778|Ensembl:ENSMUSG00000105381|miRBase:MI0023729 +102465713 Mir7236 MGI:MGI:5531387|Ensembl:ENSMUSG00000098981|miRBase:MI0023731 +102465714 Mir7238 MGI:MGI:5562781|Ensembl:ENSMUSG00000104958|miRBase:MI0023733 +102465715 Mir7239 MGI:MGI:5530886|Ensembl:ENSMUSG00000099331|miRBase:MI0023734 +102465716 Mir7242 MGI:MGI:5531191|Ensembl:ENSMUSG00000098446|miRBase:MI0023737 +102465755 Mir7646 MGI:MGI:5562788|Ensembl:ENSMUSG00000106264|miRBase:MI0024984 +102465756 Mir7647 MGI:MGI:5530729|Ensembl:ENSMUSG00000098951|miRBase:MI0024985 +102465757 Mir7649 MGI:MGI:5562774|Ensembl:ENSMUSG00000098359|miRBase:MI0024987 +102465758 Gm25500 MGI:MGI:5455277|Ensembl:ENSMUSG00000105847|miRBase:MI0024988 +102465759 Mir7651 MGI:MGI:5531046|Ensembl:ENSMUSG00000098516|miRBase:MI0024989 +102465760 Mir7652 MGI:MGI:5531314|Ensembl:ENSMUSG00000098906|miRBase:MI0024992 +102465761 Mir7653 MGI:MGI:5531282|Ensembl:ENSMUSG00000099101|miRBase:MI0024993 +102465762 Mir7654 MGI:MGI:5531130|Ensembl:ENSMUSG00000098917|miRBase:MI0024994 +102465763 Mir7656 MGI:MGI:5530996|Ensembl:ENSMUSG00000098251|miRBase:MI0024996 +102465764 Mir7657 MGI:MGI:5562759|Ensembl:ENSMUSG00000104773|miRBase:MI0024997 +102465765 Mir7659 MGI:MGI:5530815|Ensembl:ENSMUSG00000098885|miRBase:MI0024999 +102465766 Mir7661 MGI:MGI:5562770|Ensembl:ENSMUSG00000105697|miRBase:MI0025001 +102465767 Mir7662 MGI:MGI:5531258|Ensembl:ENSMUSG00000099185|miRBase:MI0025002 +102465768 Mir7663 MGI:MGI:5531416|Ensembl:ENSMUSG00000098714|miRBase:MI0025003 +102465769 Mir7667 MGI:MGI:5531138|Ensembl:ENSMUSG00000098764|miRBase:MI0025007 +102465770 Mir7668 MGI:MGI:5531343|Ensembl:ENSMUSG00000098873|miRBase:MI0025008 +102465771 Mir7669 MGI:MGI:5531378|Ensembl:ENSMUSG00000098397|miRBase:MI0025009 +102465772 Mir7671 MGI:MGI:5531184|Ensembl:ENSMUSG00000099153|miRBase:MI0025011 +102465773 Mir7672 MGI:MGI:5530696|Ensembl:ENSMUSG00000098751|miRBase:MI0025012 +102465774 Mir3569 MGI:MGI:5530661|Ensembl:ENSMUSG00000098553|miRBase:MI0025014 +102465775 Mir7675 MGI:MGI:5531347|Ensembl:ENSMUSG00000098879|miRBase:MI0025016 +102465776 Mir7676-1 MGI:MGI:5530982|Ensembl:ENSMUSG00000098996|miRBase:MI0025017 +102465777 Mir129b MGI:MGI:5562757|Ensembl:ENSMUSG00000106336|miRBase:MI0025019 +102465778 Mir1191b MGI:MGI:5562728|Ensembl:ENSMUSG00000105379|miRBase:MI0025021 +102465779 Mir7677 MGI:MGI:5530782|Ensembl:ENSMUSG00000098826|miRBase:MI0025022 +102465780 Mir7678 MGI:MGI:5530770|Ensembl:ENSMUSG00000098489|miRBase:MI0025023 +102465781 Mir7680 MGI:MGI:5530799|Ensembl:ENSMUSG00000098400|miRBase:MI0025025 +102465782 Mir3620 MGI:MGI:5531366|Ensembl:ENSMUSG00000099172|miRBase:MI0025027 +102465783 Mir7681 MGI:MGI:5531188|Ensembl:ENSMUSG00000098443|miRBase:MI0025029 +102465784 Mir7683 MGI:MGI:5531332|Ensembl:ENSMUSG00000098316|miRBase:MI0025031 +102465785 Mir216c MGI:MGI:5562730|Ensembl:ENSMUSG00000106400|miRBase:MI0025032 +102465786 Mir7684 MGI:MGI:5531255|Ensembl:ENSMUSG00000098677|miRBase:MI0025033 +102465787 Mir126b MGI:MGI:5562755|Ensembl:ENSMUSG00000105799|miRBase:MI0025035 +102465788 Mir7686 Ensembl:ENSMUSG00000105165|miRBase:MI0025037 +102465789 Mir290b MGI:MGI:5562775|Ensembl:ENSMUSG00000106340|miRBase:MI0025038 +102465790 Mir1258 MGI:MGI:5530753|Ensembl:ENSMUSG00000099196|miRBase:MI0025040 +102465791 Mir7688 MGI:MGI:5531256|Ensembl:ENSMUSG00000098679|miRBase:MI0025041 +102465792 Mir7689 MGI:MGI:5530816|Ensembl:ENSMUSG00000098884|miRBase:MI0025042 +102465883 Mir8090 MGI:MGI:5531244|Ensembl:ENSMUSG00000099069|miRBase:MI0026017 +102465884 Mir8091 MGI:MGI:5530957|Ensembl:ENSMUSG00000098286|miRBase:MI0026018 +102465885 Mir8093 MGI:MGI:5530930|Ensembl:ENSMUSG00000098972|miRBase:MI0026020 +102465886 Mir8094 MGI:MGI:5530895|Ensembl:ENSMUSG00000098269|miRBase:MI0026021 +102465887 Mir8095 MGI:MGI:5530948|Ensembl:ENSMUSG00000099071|miRBase:MI0026022 +102465888 Mir8097 MGI:MGI:5530879|Ensembl:ENSMUSG00000098457|miRBase:MI0026025 +102465889 Mir8098 MGI:MGI:5530844|Ensembl:ENSMUSG00000099245|miRBase:MI0026026 +102465890 Mir8099-1 MGI:MGI:5531299|Ensembl:ENSMUSG00000098498|miRBase:MI0026027 +102465891 Mir497b MGI:MGI:5531119|Ensembl:ENSMUSG00000070109|miRBase:MI0026030 +102465892 Mir8101 MGI:MGI:5531087|Ensembl:ENSMUSG00000098863|miRBase:MI0026031 +102465893 Mir8103 MGI:MGI:5531223|Ensembl:ENSMUSG00000098769|miRBase:MI0026033 +102465894 Mir8105 MGI:MGI:5530728|Ensembl:ENSMUSG00000098957|miRBase:MI0026035 +102465895 Gm24148 MGI:MGI:5453925|Ensembl:ENSMUSG00000104627|miRBase:MI0026036 +102465896 Mir8106 MGI:MGI:5530976|Ensembl:ENSMUSG00000098922|miRBase:MI0026037 +102465897 Mir1668 MGI:MGI:5530972|Ensembl:ENSMUSG00000098465|miRBase:MI0026040 +102465898 Mir8109 MGI:MGI:5530877|Ensembl:ENSMUSG00000098388|miRBase:MI0026041 +102465899 Mir8110 MGI:MGI:5530953|Ensembl:ENSMUSG00000099078|miRBase:MI0026042 +102465900 Mir8112 MGI:MGI:5531121|Ensembl:ENSMUSG00000098623|miRBase:MI0026044 +102465901 Mir8113 MGI:MGI:5530776|Ensembl:ENSMUSG00000098856|miRBase:MI0026045 +102465902 Mir8115 MGI:MGI:5531394|Ensembl:ENSMUSG00000099324|miRBase:MI0026047 +102465903 Mir8117 MGI:MGI:5530705|Ensembl:ENSMUSG00000099124|miRBase:MI0026049 +102465904 Mir8118 MGI:MGI:5531336|Ensembl:ENSMUSG00000098310|miRBase:MI0026050 +102465905 Mir8120 MGI:MGI:5531019|Ensembl:ENSMUSG00000098944|miRBase:MI0026052 +102465959 Mir6236 MGI:MGI:5530929|Ensembl:ENSMUSG00000098973|miRBase:MI0021583 +102465961 Mir6341 MGI:MGI:5530644|Ensembl:ENSMUSG00000098555|miRBase:MI0021869 +102465962 Mir6362 MGI:MGI:5531194|Ensembl:ENSMUSG00000098448|miRBase:MI0021891 +102465963 Mir6382 MGI:MGI:5530701|Ensembl:ENSMUSG00000099128|miRBase:MI0021913 +102465964 Mir6419 MGI:MGI:5531095|Ensembl:ENSMUSG00000099161|miRBase:MI0021957 +102465968 Mir6537 MGI:MGI:5531190|Ensembl:ENSMUSG00000098441|miRBase:MI0022353 +102465979 Mir6915 MGI:MGI:5562729|Ensembl:ENSMUSG00000106600|miRBase:MI0022762 +102465980 Mir6937 MGI:MGI:5530830|Ensembl:ENSMUSG00000098579|miRBase:MI0022784 +102465981 Mir6959 MGI:MGI:5531189|Ensembl:ENSMUSG00000098442|miRBase:MI0022806 +102465982 Mir7002 MGI:MGI:5530811|Ensembl:ENSMUSG00000098464|miRBase:MI0022850 +102465983 Mir7023 MGI:MGI:5531294|Ensembl:ENSMUSG00000098580|miRBase:MI0022872 +102465984 Mir7067 MGI:MGI:5531413|Ensembl:ENSMUSG00000098710|miRBase:MI0022916 +102465987 Mir7215 MGI:MGI:5562726|Ensembl:ENSMUSG00000105329|miRBase:MI0023710 +102465989 Mir7664 MGI:MGI:5531397|Ensembl:ENSMUSG00000099320|miRBase:MI0025004 +102465990 Mir6715 MGI:MGI:5530856|Ensembl:ENSMUSG00000098289|miRBase:MI0025026 +102465996 Mir8100 MGI:MGI:5531020|Ensembl:ENSMUSG00000098942|miRBase:MI0026029 +102465997 Mir8119 MGI:MGI:5530949|Ensembl:ENSMUSG00000099070|miRBase:MI0026051 +102466147 Mir6237 MGI:MGI:5530793|Ensembl:ENSMUSG00000098408|miRBase:MI0021584 +102466151 Mir6337 MGI:MGI:5531259|Ensembl:ENSMUSG00000099184|miRBase:MI0021865 +102466152 Mir6357 MGI:MGI:5530715|Ensembl:ENSMUSG00000098721|miRBase:MI0021885 +102466153 Mir6365 MGI:MGI:5531065|Ensembl:ENSMUSG00000099214|miRBase:MI0021894 +102466154 Mir6372 MGI:MGI:5530740|Ensembl:ENSMUSG00000099015|miRBase:MI0021901 +102466155 Mir6378 MGI:MGI:5531088|Ensembl:ENSMUSG00000098862|miRBase:MI0021909 +102466156 Mir6389 MGI:MGI:5531328|Ensembl:ENSMUSG00000099203|miRBase:MI0021922 +102466157 Mir6402 MGI:MGI:5531146|Ensembl:ENSMUSG00000098563|miRBase:MI0021938 +102466158 Mir6408 MGI:MGI:5530833|Ensembl:ENSMUSG00000099279|miRBase:MI0021945 +102466159 Mir6415 MGI:MGI:5531096|Ensembl:ENSMUSG00000099160|miRBase:MI0021953 +102466172 Mir6540 MGI:MGI:5531162|Ensembl:ENSMUSG00000098300|miRBase:MI0022356 +102466206 Mir6903 MGI:MGI:5531179|Ensembl:ENSMUSG00000098606|miRBase:MI0022750 +102466207 Mir6911 MGI:MGI:5531204|Ensembl:ENSMUSG00000098672|miRBase:MI0022758 +102466208 Mir6924 MGI:MGI:5562732|Ensembl:ENSMUSG00000104996|miRBase:MI0022771 +102466209 Mir6947 MGI:MGI:5562741|Ensembl:ENSMUSG00000104926|miRBase:MI0022794 +102466210 Mir6955 MGI:MGI:5531151|Ensembl:ENSMUSG00000099267|miRBase:MI0022802 +102466211 Gm27775 MGI:MGI:5531157|Ensembl:ENSMUSG00000098586|miRBase:MI0022815 +102466212 Mir6983 MGI:MGI:5530878|Ensembl:ENSMUSG00000098389|miRBase:MI0022831 +102466213 Mir6990 MGI:MGI:5531108|Ensembl:ENSMUSG00000098413|miRBase:MI0022838 +102466214 Mir6998 MGI:MGI:5531406|Ensembl:ENSMUSG00000098904|miRBase:MI0022846 +102466215 Mir7017 MGI:MGI:5531327|Ensembl:ENSMUSG00000099202|miRBase:MI0022866 +102466216 Mir7026 MGI:MGI:5531370|Ensembl:ENSMUSG00000099284|miRBase:MI0022875 +102466217 Mir7033 MGI:MGI:5531069|Ensembl:ENSMUSG00000099212|miRBase:MI0022882 +102466218 Mir7054 MGI:MGI:5530939|Ensembl:ENSMUSG00000098839|miRBase:MI0022903 +102466219 Mir7061 MGI:MGI:5562779|Ensembl:ENSMUSG00000104914|miRBase:MI0022910 +102466220 Mir7069 MGI:MGI:5531159|Ensembl:ENSMUSG00000098331|miRBase:MI0022919 +102466221 Mir7084 MGI:MGI:5531360|Ensembl:ENSMUSG00000098646|miRBase:MI0022934 +102466228 Mir7218 MGI:MGI:5562749|Ensembl:ENSMUSG00000106215|miRBase:MI0023713 +102466229 Mir7225 MGI:MGI:5530881|Ensembl:ENSMUSG00000098381|miRBase:MI0023720 +102466236 Mir7658 MGI:MGI:5530727|Ensembl:ENSMUSG00000098954|miRBase:MI0024998 +102466237 Mir7666 MGI:MGI:5531297|Ensembl:ENSMUSG00000098431|miRBase:MI0025006 +102466238 Mir7673 MGI:MGI:5530951|Ensembl:ENSMUSG00000099072|miRBase:MI0025013 +102466239 Mir465d MGI:MGI:5562786|Ensembl:ENSMUSG00000106642|miRBase:MI0025028 +102466240 Mir7685 MGI:MGI:5531139|Ensembl:ENSMUSG00000098765|miRBase:MI0025036 +102466241 Mir7243 MGI:MGI:5530745|Ensembl:ENSMUSG00000098521|miRBase:MI0025043 +102466254 Mir3473f MGI:MGI:5531228|Ensembl:ENSMUSG00000098344|miRBase:MI0026016 +102466255 Mir1291 MGI:MGI:5562744|Ensembl:ENSMUSG00000106463|miRBase:MI0026023 +102466256 Mir8102 MGI:MGI:5531177|Ensembl:ENSMUSG00000098919|miRBase:MI0026032 +102466257 Mir8114 MGI:MGI:5530764|Ensembl:ENSMUSG00000099227|miRBase:MI0026046 +102466258 Mir3473g MGI:MGI:5531133|Ensembl:ENSMUSG00000098896|miRBase:MI0026054 +102466272 Mir7045 MGI:MGI:5531140|Ensembl:ENSMUSG00000098762|miRBase:MI0022894 +102466619 Mir6238 MGI:MGI:5531364|Ensembl:ENSMUSG00000099176|miRBase:MI0021585 +102466620 Mir6240 MGI:MGI:5531232|Ensembl:ENSMUSG00000098343|miRBase:MI0021587 +102466627 Mir6335 MGI:MGI:5531218|Ensembl:ENSMUSG00000098734|miRBase:MI0021862 +102466628 Mir6339 MGI:MGI:5531230|Ensembl:ENSMUSG00000098347|miRBase:MI0021867 +102466629 Mir6344 MGI:MGI:5531222|Ensembl:ENSMUSG00000098797|miRBase:MI0021872 +102466630 Mir6345 MGI:MGI:5531201|Ensembl:ENSMUSG00000098689|miRBase:MI0021873 +102466631 Mir6349 MGI:MGI:5530940|Ensembl:ENSMUSG00000098833|miRBase:MI0021877 +102466632 Mir6354 MGI:MGI:5530664|Ensembl:ENSMUSG00000098829|miRBase:MI0021882 +102466633 Mir6359 MGI:MGI:5530710|Ensembl:ENSMUSG00000098676|miRBase:MI0021887 +102466634 Mir6363 MGI:MGI:5531408|Ensembl:ENSMUSG00000098482|miRBase:MI0021892 +102466635 Mir6368 MGI:MGI:5531182|Ensembl:ENSMUSG00000099158|miRBase:MI0021897 +102466636 Mir6373 MGI:MGI:5531252|Ensembl:ENSMUSG00000098533|miRBase:MI0021902 +102466637 Mir21b MGI:MGI:5531333|Ensembl:ENSMUSG00000098315|miRBase:MI0021906 +102466638 Mir6380 MGI:MGI:5530738|Ensembl:ENSMUSG00000099011|miRBase:MI0021911 +102466639 Mir6385 MGI:MGI:5531403|Ensembl:ENSMUSG00000098886|miRBase:MI0021916 +102466640 Mir130c MGI:MGI:5531023|Ensembl:ENSMUSG00000098362|miRBase:MI0021917 +102466641 Mir5124b MGI:MGI:5531063|Ensembl:ENSMUSG00000099218|miRBase:MI0021921 +102466642 Mir6392 MGI:MGI:5530813|Ensembl:ENSMUSG00000098882|miRBase:MI0021926 +102466643 Mir6396 MGI:MGI:5531320|Ensembl:ENSMUSG00000098500|miRBase:MI0021931 +102466644 Mir6400 MGI:MGI:5530807|Ensembl:ENSMUSG00000098929|miRBase:MI0021936 +102466645 Mir6405 MGI:MGI:5530731|Ensembl:ENSMUSG00000098952|miRBase:MI0021941 +102466646 Mir6409 MGI:MGI:5531169|Ensembl:ENSMUSG00000098817|miRBase:MI0021946 +102466647 Mir6413 MGI:MGI:5530814|Ensembl:ENSMUSG00000098887|miRBase:MI0021950 +102466648 Mir6417 MGI:MGI:5530716|Ensembl:ENSMUSG00000098726|miRBase:MI0021955 +102466649 Mir451b MGI:MGI:5562734|Ensembl:ENSMUSG00000104813|miRBase:MI0021960 +102466650 Mir30f MGI:MGI:5562761|Ensembl:ENSMUSG00000105585|miRBase:MI0021961 +102466676 Mir6538 MGI:MGI:5530821|Ensembl:ENSMUSG00000098771|miRBase:MI0022354 +102466677 Mir3473e MGI:MGI:5530804|Ensembl:ENSMUSG00000099301|miRBase:MI0022357 +102466760 Mir6899 MGI:MGI:5530766|Ensembl:ENSMUSG00000098487|miRBase:MI0022746 +102466761 Mir6904 MGI:MGI:5530808|Ensembl:ENSMUSG00000098926|miRBase:MI0022751 +102466762 Mir6908 MGI:MGI:5531209|Ensembl:ENSMUSG00000098279|miRBase:MI0022755 +102466763 Mir6913 MGI:MGI:5531170|Ensembl:ENSMUSG00000098811|miRBase:MI0022760 +102466764 Mir6918 MGI:MGI:5531350|Ensembl:ENSMUSG00000098296|miRBase:MI0022765 +102466765 Mir6919 MGI:MGI:5531271|Ensembl:ENSMUSG00000098474|miRBase:MI0022766 +102466766 Mir6923 MGI:MGI:5530694|Ensembl:ENSMUSG00000098855|miRBase:MI0022770 +102466767 Mir6928 MGI:MGI:5531110|Ensembl:ENSMUSG00000098415|miRBase:MI0022775 +102466768 Mir6933 MGI:MGI:5531238|Ensembl:ENSMUSG00000098958|miRBase:MI0022780 +102466769 Mir6938 MGI:MGI:5530901|Ensembl:ENSMUSG00000098263|miRBase:MI0022785 +102466770 Mir6943 MGI:MGI:5531173|Ensembl:ENSMUSG00000099058|miRBase:MI0022790 +102466771 Mir6948 MGI:MGI:5562742|Ensembl:ENSMUSG00000106169|miRBase:MI0022795 +102466772 Mir6952 MGI:MGI:5531330|Ensembl:ENSMUSG00000098451|miRBase:MI0022799 +102466773 Mir6957 MGI:MGI:5531277|Ensembl:ENSMUSG00000098631|miRBase:MI0022804 +102466774 Mir6962 MGI:MGI:5562745|Ensembl:ENSMUSG00000106563|miRBase:MI0022809 +102466775 Mir6963 MGI:MGI:5531106|Ensembl:ENSMUSG00000098419|miRBase:MI0022810 +102466776 Mir6966 MGI:MGI:5530654|Ensembl:ENSMUSG00000098329|miRBase:MI0022814 +102466777 Mir6971 MGI:MGI:5530689|Ensembl:ENSMUSG00000098458|miRBase:MI0022819 +102466778 Mir6976 MGI:MGI:5562751|Ensembl:ENSMUSG00000106514|miRBase:MI0022824 +102466779 Mir6981 MGI:MGI:5530991|Ensembl:ENSMUSG00000098608|miRBase:MI0022829 +102466780 Mir6986 MGI:MGI:5531091|Ensembl:ENSMUSG00000098346|miRBase:MI0022834 +102466781 Mir6991 MGI:MGI:5531348|Ensembl:ENSMUSG00000098293|miRBase:MI0022839 +102466782 Mir6995 MGI:MGI:5530958|Ensembl:ENSMUSG00000098786|miRBase:MI0022843 +102466783 Mir7000 MGI:MGI:5530720|Ensembl:ENSMUSG00000099093|miRBase:MI0022848 +102466784 Mir7004 MGI:MGI:5562758|Ensembl:ENSMUSG00000105496|miRBase:MI0022853 +102466785 Mir7005 MGI:MGI:5531217|Ensembl:ENSMUSG00000098735|miRBase:MI0022854 +102466786 Mir7009 MGI:MGI:5530854|Ensembl:ENSMUSG00000098808|miRBase:MI0022858 +102466787 Mir7014 MGI:MGI:5531219|Ensembl:ENSMUSG00000098737|miRBase:MI0022863 +102466788 Mir7019 MGI:MGI:5531329|Ensembl:ENSMUSG00000099200|miRBase:MI0022868 +102466789 Mir7024 MGI:MGI:5530941|Ensembl:ENSMUSG00000098830|miRBase:MI0022873 +102466790 Mir7029 MGI:MGI:5530675|Ensembl:ENSMUSG00000099047|miRBase:MI0022878 +102466791 Mir7034 MGI:MGI:5530754|Ensembl:ENSMUSG00000099197|miRBase:MI0022883 +102466792 Mir7038 MGI:MGI:5531337|Ensembl:ENSMUSG00000098319|miRBase:MI0022887 +102466793 Mir7043 MGI:MGI:5531158|Ensembl:ENSMUSG00000098334|miRBase:MI0022892 +102466794 Mir7048 MGI:MGI:5530656|Ensembl:ENSMUSG00000098325|miRBase:MI0022897 +102466795 Mir7049 MGI:MGI:5530659|Ensembl:ENSMUSG00000098558|miRBase:MI0022898 +102466796 Mir7053 MGI:MGI:5530885|Ensembl:ENSMUSG00000099330|miRBase:MI0022902 +102466797 Mir7058 MGI:MGI:5531148|Ensembl:ENSMUSG00000099017|miRBase:MI0022907 +102466798 Mir7063 MGI:MGI:5531036|Ensembl:ENSMUSG00000098759|miRBase:MI0022912 +102466799 Mir6769b MGI:MGI:5530928|Ensembl:ENSMUSG00000098976|miRBase:MI0022917 +102466800 Mir7072 MGI:MGI:5531047|Ensembl:ENSMUSG00000098511|miRBase:MI0022922 +102466801 Mir7077 MGI:MGI:5531156|Ensembl:ENSMUSG00000099062|miRBase:MI0022927 +102466802 Mir7081 MGI:MGI:5531286|Ensembl:ENSMUSG00000099147|miRBase:MI0022931 +102466803 Mir7086 MGI:MGI:5531025|Ensembl:ENSMUSG00000098361|miRBase:MI0022936 +102466804 Mir7091 MGI:MGI:5530763|Ensembl:ENSMUSG00000099226|miRBase:MI0022941 +102466805 Mir7093 MGI:MGI:5530835|Ensembl:ENSMUSG00000099272|miRBase:MI0022943 +102466808 Mir7117 MGI:MGI:5531111|Ensembl:ENSMUSG00000098416|miRBase:MI0022968 +102466817 Mir7211 MGI:MGI:5530918|Ensembl:ENSMUSG00000098544|miRBase:MI0023706 +102466818 Mir7216 MGI:MGI:5530937|Ensembl:ENSMUSG00000099237|miRBase:MI0023711 +102466819 Mir7221 MGI:MGI:5530760|Ensembl:ENSMUSG00000099223|miRBase:MI0023716 +102466820 Mir7226 MGI:MGI:5531012|Ensembl:ENSMUSG00000098596|miRBase:MI0023721 +102466821 Mir7230 MGI:MGI:5562766|Ensembl:ENSMUSG00000104840|miRBase:MI0023725 +102466822 Mir7235 MGI:MGI:5531368|Ensembl:ENSMUSG00000099286|miRBase:MI0023730 +102466823 Mir7240 MGI:MGI:5530869|Ensembl:ENSMUSG00000099031|miRBase:MI0023735 +102466824 Mir7241 MGI:MGI:5531300|Ensembl:ENSMUSG00000098937|miRBase:MI0023736 +102466836 Mir7578 MGI:MGI:5490891|Ensembl:ENSMUSG00000098812|miRBase:MI0024714 +102466838 Mir7648 MGI:MGI:5531118|Ensembl:ENSMUSG00000099319|miRBase:MI0024986 +102466839 Mir219b MGI:MGI:5562756|Ensembl:ENSMUSG00000105010|miRBase:MI0024990 +102466840 Mir7655 MGI:MGI:5531176|Ensembl:ENSMUSG00000099050|miRBase:MI0024995 +102466841 Mir7660 MGI:MGI:5531094|Ensembl:ENSMUSG00000099163|miRBase:MI0025000 +102466842 Mir7665 MGI:MGI:5530860|Ensembl:ENSMUSG00000098632|miRBase:MI0025005 +102466843 Mir7670 MGI:MGI:5531089|Ensembl:ENSMUSG00000098285|miRBase:MI0025010 +102466844 Mir7674 MGI:MGI:5530945|Ensembl:ENSMUSG00000099075|miRBase:MI0025015 +102466845 Mir7676-2 MGI:MGI:5531172|Ensembl:ENSMUSG00000099059|miRBase:MI0025018 +102466846 Mir7679 MGI:MGI:5531290|Ensembl:ENSMUSG00000098840|miRBase:MI0025024 +102466847 Mir7682 MGI:MGI:5562724|Ensembl:ENSMUSG00000106406|miRBase:MI0025030 +102466848 Mir219c MGI:MGI:5562750|Ensembl:ENSMUSG00000105964|miRBase:MI0025034 +102466849 Mir7687 MGI:MGI:5530955|Ensembl:ENSMUSG00000098280|miRBase:MI0025039 +102466881 Mir8092 MGI:MGI:5530789|Ensembl:ENSMUSG00000099118|miRBase:MI0026019 +102466882 Mir8096 MGI:MGI:5530861|Ensembl:ENSMUSG00000098634|miRBase:MI0026024 +102466883 Mir142b MGI:MGI:5531132|Ensembl:ENSMUSG00000065420|miRBase:MI0026028 +102466884 Mir8104 MGI:MGI:5530762|Ensembl:ENSMUSG00000099225|miRBase:MI0026034 +102466885 Mir8107 MGI:MGI:5530837|Ensembl:ENSMUSG00000099275|miRBase:MI0026038 +102466886 Mir8111 MGI:MGI:5531205|Ensembl:ENSMUSG00000098823|miRBase:MI0026043 +102466887 Mir8116 MGI:MGI:5530867|Ensembl:ENSMUSG00000099145|miRBase:MI0026048 +102466888 Mir8099-2 MGI:MGI:5531074|Ensembl:ENSMUSG00000098931|miRBase:MI0026053 +102466907 Mir6399 MGI:MGI:5531049|Ensembl:ENSMUSG00000098513|miRBase:MI0021935 +102466913 Mir6980 MGI:MGI:5531351|Ensembl:ENSMUSG00000098297|miRBase:MI0022828 +102466914 Mir7088 MGI:MGI:5530959|Ensembl:ENSMUSG00000098787|miRBase:MI0022938 +102466915 Mir7237 MGI:MGI:5530864|Ensembl:ENSMUSG00000099140|miRBase:MI0023732 +102466969 Mir6350 MGI:MGI:5531340|Ensembl:ENSMUSG00000098876|miRBase:MI0021878 +102466970 Mir1957b MGI:MGI:5531107|Ensembl:ENSMUSG00000098410|miRBase:MI0021929 +102466987 Mir6896 MGI:MGI:5562721|Ensembl:ENSMUSG00000105982|miRBase:MI0022743 +102466988 Mir6931 MGI:MGI:5530685|Ensembl:ENSMUSG00000098613|miRBase:MI0022778 +102466989 Mir6940 MGI:MGI:5531037|Ensembl:ENSMUSG00000099165|miRBase:MI0022787 +102466990 Mir6974 MGI:MGI:5531040|Ensembl:ENSMUSG00000099006|miRBase:MI0022822 +102466991 Mir7010 MGI:MGI:5531411|Ensembl:ENSMUSG00000098712|miRBase:MI0022859 +102466992 Mir7041 MGI:MGI:5531254|Ensembl:ENSMUSG00000098531|miRBase:MI0022890 +102466993 Mir7076 MGI:MGI:5530700|Ensembl:ENSMUSG00000099129|miRBase:MI0022926 +102466996 Mir7233 MGI:MGI:5562773|Ensembl:ENSMUSG00000104804|miRBase:MI0023728 +102466998 Mir6546 MGI:MGI:5530790|Ensembl:ENSMUSG00000099119|miRBase:MI0024983 +102466999 Mir7036b MGI:MGI:5531007|Ensembl:ENSMUSG00000099082|miRBase:MI0024991 +102467000 Mir292b MGI:MGI:5562776|Ensembl:ENSMUSG00000104747|miRBase:MI0025020 +102467006 Mir8108 MGI:MGI:5530866|Ensembl:ENSMUSG00000099142|miRBase:MI0026039 +102467227 n-TAagc2 MGI:MGI:4413675 +102467228 n-TAagc4 MGI:MGI:4413677 +102467229 n-TAagc6 MGI:MGI:4413679 +102467230 n-TAagc8 MGI:MGI:4413681 +102467231 n-TAagc10 MGI:MGI:4413683 +102467232 n-TAagc12 MGI:MGI:4413685 +102467233 n-TAagc14 MGI:MGI:4413687 +102467234 n-TAagc17 MGI:MGI:4413690 +102467235 n-TAcgc1 MGI:MGI:4413693 +102467236 n-TAcgc3 MGI:MGI:4413695 +102467237 n-TAcgc5 MGI:MGI:4413697 +102467238 n-TAcgc8 MGI:MGI:4413700 +102467239 n-TAcgc10 MGI:MGI:4413702 +102467240 n-TAtgc2 MGI:MGI:4413704 +102467241 n-TAtgc4 MGI:MGI:4413706 +102467242 n-TAtgc7 MGI:MGI:4413709 +102467243 n-TAtgc9 MGI:MGI:4413711 +102467244 n-TAtgc11 MGI:MGI:4413713 +102467245 n-TRacg4 MGI:MGI:4413717 +102467246 n-TRacg6 MGI:MGI:4413719 +102467247 n-TRccg2 MGI:MGI:4413721 +102467248 n-TRcct1 MGI:MGI:4413723 +102467249 n-TRcct4 MGI:MGI:4413726 +102467250 n-TRtcg1 MGI:MGI:4413728 +102467251 n-TRtcg3 MGI:MGI:4413730 +102467252 n-TRtcg5 MGI:MGI:4413732 +102467253 n-TRtct2 MGI:MGI:4413735 +102467254 n-TNgtt1 MGI:MGI:4413738 +102467255 n-TNgtt3 MGI:MGI:4413740 +102467256 n-TNgtt5 MGI:MGI:4413742 +102467257 n-TNgtt8 MGI:MGI:4413745 +102467258 n-TNgtt10 MGI:MGI:4413747 +102467259 n-TNgtt12 MGI:MGI:4413749 +102467260 n-TNgtt14 MGI:MGI:4413751 +102467261 n-TDgtc3 MGI:MGI:4413754 +102467262 n-TDgtc5 MGI:MGI:4413756 +102467263 n-TDgtc7 MGI:MGI:4413758 +102467265 n-TDgtc14 MGI:MGI:4413765 +102467266 n-TDgtc16 MGI:MGI:4413767 +102467267 n-TCgca2 MGI:MGI:4413769 +102467268 n-TCgca5 MGI:MGI:4413772 +102467269 n-TCgca7 MGI:MGI:4413774 +102467270 n-TCgca9 MGI:MGI:4413776 +102467271 n-TCgca11 MGI:MGI:4413778 +102467272 n-TCgca14 MGI:MGI:4413781 +102467273 n-TCgca17 MGI:MGI:4413784 +102467274 n-TCgca19 MGI:MGI:4413786 +102467275 n-TCgca22 MGI:MGI:4413789 +102467276 n-TCgca24 MGI:MGI:4413791 +102467277 n-TCgca25 MGI:MGI:4413792 +102467278 n-TCgca27 MGI:MGI:4413794 +102467279 n-TCgca29 MGI:MGI:4413796 +102467280 n-TCgca32 MGI:MGI:4413799 +102467281 n-TCgca34 MGI:MGI:4413801 +102467282 n-TCgca36 MGI:MGI:4413803 +102467283 n-TCgca41 MGI:MGI:4413808 +102467284 n-Tcgca44 MGI:MGI:4413811 +102467285 n-TCgca46 MGI:MGI:4413813 +102467286 n-TCgca49 MGI:MGI:4413816 +102467287 n-TCgca50 MGI:MGI:4413817 +102467288 n-TCgca52 MGI:MGI:4413819 +102467289 n-TCgca54 MGI:MGI:4413821 +102467290 n-TCgca56 MGI:MGI:4413823 +102467291 n-TQctg2 MGI:MGI:4413826 +102467292 n-TQctg5 MGI:MGI:4413829 +102467293 n-TQctg7 MGI:MGI:4413831 +102467294 n-TQctg9 MGI:MGI:4413833 +102467295 n-TQttg2 MGI:MGI:4413836 +102467296 n-TQttg4 MGI:MGI:4413838 +102467299 n-TEctc5 MGI:MGI:4413845 +102467300 n-TEctc7 MGI:MGI:4413847 +102467301 n-TEctc9 MGI:MGI:4413849 +102467302 n-TEttc3 MGI:MGI:4413854 +102467303 n-TEttc1 MGI:MGI:4413856 +102467304 n-TEttc5 MGI:MGI:4413858 +102467305 n-TEttc8 MGI:MGI:4413861 +102467306 n-TGccc2 MGI:MGI:4413863 +102467307 n-TGccc1 MGI:MGI:4413865 +102467308 n-TGccc6 MGI:MGI:4413867 +102467309 n-TGccc4 MGI:MGI:4413869 +102467310 n-TGgcc3 MGI:MGI:4413872 +102467311 n-TGgcc6 MGI:MGI:4413875 +102467312 n-TGgcc7 MGI:MGI:4413876 +102467313 n-TGgcc9 MGI:MGI:4413878 +102467314 n-TGgcc12 MGI:MGI:4413881 +102467315 n-TGgcc14 MGI:MGI:4413883 +102467316 n-TGtcc2 MGI:MGI:4413885 +102467317 n-TGtcc4 MGI:MGI:4413887 +102467318 n-TGtcc7 MGI:MGI:4413890 +102467319 n-THgtg4 MGI:MGI:4413894 +102467320 n-THgtg7 MGI:MGI:4413897 +102467321 n-THgtg1 MGI:MGI:4413901 +102467322 n-TIaat4 MGI:MGI:4413905 +102467323 n-TIaat6 MGI:MGI:4413907 +102467324 n-TIaat8 MGI:MGI:4413909 +102467326 n-TIaat13 MGI:MGI:4413914 +102467327 n-TIaat15 MGI:MGI:4413916 +102467328 n-TIaat17 MGI:MGI:4413918 +102467329 n-TLaag3 MGI:MGI:4413921 +102467330 n-TLaag6 MGI:MGI:4413924 +102467331 n-TLaag7 MGI:MGI:4413925 +102467332 n-TLcaa4 MGI:MGI:4413927 +102467333 n-TLcaa3 MGI:MGI:4413930 +102467334 n-TLcag2 MGI:MGI:4413932 +102467335 n-TLcag4 MGI:MGI:4413934 +102467336 n-TLcag6 MGI:MGI:4413936 +102467337 n-TLcag9 MGI:MGI:4413939 +102467338 n-TLtaa1 MGI:MGI:4413941 +102467339 n-TLtaa3 MGI:MGI:4413943 +102467340 n-TLtag2 MGI:MGI:4413946 +102467341 n-TKctt3 MGI:MGI:4413950 +102467342 n-TKctt4 MGI:MGI:4413951 +102467343 n-TKctt6 MGI:MGI:4413953 +102467344 n-TKctt9 MGI:MGI:4413956 +102467345 n-TKctt11 MGI:MGI:4413958 +102467346 n-TKctt13 MGI:MGI:4413960 +102467347 n-TKctt15 MGI:MGI:4413962 +102467348 n-TKctt18 MGI:MGI:4413965 +102467349 n-TKctt21 MGI:MGI:4413968 +102467350 n-TKttt23 MGI:MGI:4413970 +102467351 n-TKctt25 MGI:MGI:4413972 +102467352 n-TKctt28 MGI:MGI:4413975 +102467353 n-TKctt30 MGI:MGI:4413977 +102467355 n-TMcat4 MGI:MGI:4413981 +102467356 n-TMcat7 MGI:MGI:4413984 +102467357 n-TMcat9 MGI:MGI:4413986 +102467358 n-TMcat11 MGI:MGI:4413988 +102467359 n-TMcat14 MGI:MGI:4413991 +102467360 n-TMcat17 MGI:MGI:4413994 +102467361 n-TFgaa2 MGI:MGI:4413997 +102467362 n-TFgaa4 MGI:MGI:4413999 +102467363 n-TFgaa7 MGI:MGI:4414002 +102467364 n-TPagg2 MGI:MGI:4414004 +102467365 n-TPagg3 MGI:MGI:4414005 +102467366 n-TPagg5 MGI:MGI:4414007 +102467367 n-TPagg7 MGI:MGI:4414009 +102467368 n-TPtgg1 MGI:MGI:4414013 +102467370 n-TPtgg5 MGI:MGI:4414017 +102467371 n-TPtgg8 MGI:MGI:4414020 +102467372 n-TSaga3 MGI:MGI:4414023 +102467374 n-TSaga7 MGI:MGI:4414027 +102467375 n-TSaga9 MGI:MGI:4414029 +102467376 n-TScga1 MGI:MGI:4414032 +102467377 n-TScga3 MGI:MGI:4414034 +102467378 n-TSgct3 MGI:MGI:4414037 +102467379 n-TSgct4 MGI:MGI:4414038 +102467380 n-TSgct6 MGI:MGI:4414040 +102467381 n-TSgct8 MGI:MGI:4414042 +102467382 n-TStga1 MGI:MGI:4414044 +102467383 n-Tsta1 MGI:MGI:4414047 +102467384 n-TTagt2 MGI:MGI:4414049 +102467386 n-TTagt6 MGI:MGI:4414053 +102467387 n-TTagt9 MGI:MGI:4414056 +102467388 n-TTcgt3 MGI:MGI:4414059 +102467389 n-TTcgt5 MGI:MGI:4414061 +102467390 n-TTtgt2 MGI:MGI:4414063 +102467391 n-TWcca1 MGI:MGI:4414066 +102467392 n-TWcca3 MGI:MGI:4414068 +102467393 n-TWcca5 MGI:MGI:4414070 +102467394 n-TWcca7 MGI:MGI:4414072 +102467395 n-TYgta2 MGI:MGI:4414075 +102467396 n-TYgta4 MGI:MGI:4414077 +102467397 n-TYgta6 MGI:MGI:4414079 +102467398 n-TYgta9 MGI:MGI:4414082 +102467399 n-TVaac2 MGI:MGI:4414085 +102467400 n-TVaac4 MGI:MGI:4414087 +102467401 n-TVaac6 MGI:MGI:4414089 +102467402 n-TVaac8 MGI:MGI:4414091 +102467403 n-TVcac2 MGI:MGI:4414093 +102467404 n-TVcac4 MGI:MGI:4414095 +102467405 n-TVcac6 MGI:MGI:4414097 +102467406 n-TVcac8 MGI:MGI:4414099 +102467407 n-TVcac10 MGI:MGI:4414101 +102467408 n-TVgac1 MGI:MGI:4414103 +102467409 n-TVtac2 MGI:MGI:4414105 +102467410 n-TMcat19 MGI:MGI:5432484 +102467411 n-TRtct4 MGI:MGI:4413737 +102467412 n-TCgca15 MGI:MGI:4413782 +102467413 n-TQctg4 MGI:MGI:4413828 +102467414 n-THgtg9 MGI:MGI:4413899 +102467415 n-TLaag4 MGI:MGI:4413922 +102467416 n-TKctt20 MGI:MGI:4413967 +102467417 n-TPcgg1 MGI:MGI:4414012 +102467418 n-TTcgt2 MGI:MGI:4414058 +102467419 n-TAagc16 MGI:MGI:4413689 +102467420 n-TAtgc5 MGI:MGI:4413707 +102467421 n-TRcct3 MGI:MGI:4413725 +102467422 n-TNgtt7 MGI:MGI:4413744 +102467424 n-TCgca12 MGI:MGI:4413779 +102467425 n-TCgca30 MGI:MGI:4413797 +102467426 n-TCgca48 MGI:MGI:4413815 +102467428 n-TEctc13 MGI:MGI:4413853 +102467429 n-TGgcc1 MGI:MGI:4413870 +102467430 n-TGtcc5 MGI:MGI:4413888 +102467431 n-TIaat9 MGI:MGI:4413910 +102467433 n-TLtag3 MGI:MGI:4413947 +102467434 n-TKctt17 MGI:MGI:4413964 +102467435 n-TMcat5 MGI:MGI:4413982 +102467436 n-TFgaa5 MGI:MGI:4414000 +102467437 n-TPtgg7 MGI:MGI:4414019 +102467438 n-TSgct5 MGI:MGI:4414039 +102467440 n-TTagt8 MGI:MGI:4414055 +102467441 n-TTtgt3 MGI:MGI:4414064 +102467442 n-TYgta1 MGI:MGI:4414074 +102467443 n-TVaac1 MGI:MGI:4414084 +102467444 n-TAagc19 MGI:MGI:4413692 +102467445 n-TGgcc4 MGI:MGI:4413873 +102467446 n-TYgta7 MGI:MGI:4414080 +102467447 n-TAagc1 MGI:MGI:4413674 +102467448 n-TAagc3 MGI:MGI:4413676 +102467449 n-TAagc5 MGI:MGI:4413678 +102467450 n-TAagc9 MGI:MGI:4413682 +102467451 n-TAagc11 MGI:MGI:4413684 +102467452 n-TAagc13 MGI:MGI:4413686 +102467453 n-TAagc15 MGI:MGI:4413688 +102467454 n-TAagc18 MGI:MGI:4413691 +102467455 n-TAcgc2 MGI:MGI:4413694 +102467456 n-TAcgc4 MGI:MGI:4413696 +102467457 n-TAcgc7 MGI:MGI:4413699 +102467458 n-TAcgc9 MGI:MGI:4413701 +102467459 n-TAtgc1 MGI:MGI:4413703 +102467460 n-TAtgc3 MGI:MGI:4413705 +102467461 n-TAtgc6 MGI:MGI:4413708 +102467462 n-TAtgc8 MGI:MGI:4413710 +102467463 n-TAtgc10 MGI:MGI:4413712 +102467464 n-TRacg2 MGI:MGI:4413715 +102467465 n-TRacg5 MGI:MGI:4413718 +102467466 n-TRccg1 MGI:MGI:4413720 +102467467 n-TRccg3 MGI:MGI:4413722 +102467468 n-TRcct2 MGI:MGI:4413724 +102467469 n-TRcct5 MGI:MGI:4413727 +102467470 n-TRtcg2 MGI:MGI:4413729 +102467471 n-TRtcg4 MGI:MGI:4413731 +102467472 n-TRtct1 MGI:MGI:4413734 +102467474 n-TNgtt2 MGI:MGI:4413739 +102467475 n-TNgtt4 MGI:MGI:4413741 +102467476 n-TNgtt6 MGI:MGI:4413743 +102467477 n-TNgtt9 MGI:MGI:4413746 +102467478 n-TNgtt11 MGI:MGI:4413748 +102467479 n-TNgtt13 MGI:MGI:4413750 +102467480 n-TDgtc2 MGI:MGI:4413753 +102467481 n-TDgtc4 MGI:MGI:4413755 +102467482 n-TDgtc6 MGI:MGI:4413757 +102467483 n-TDgtc9 MGI:MGI:4413760 +102467486 n-TDgtc15 MGI:MGI:4413766 +102467487 n-TCgca1 MGI:MGI:4413768 +102467488 n-TCgca4 MGI:MGI:4413771 +102467489 n-TCgca6 MGI:MGI:4413773 +102467490 n-TCgca8 MGI:MGI:4413775 +102467491 n-TCgca10 MGI:MGI:4413777 +102467492 n-TCgca13 MGI:MGI:4413780 +102467493 n-TCgca16 MGI:MGI:4413783 +102467494 n-TCgca18 MGI:MGI:4413785 +102467495 n-TCgca20 MGI:MGI:4413787 +102467496 n-TCgca23 MGI:MGI:4413790 +102467497 n-TCgca26 MGI:MGI:4413793 +102467498 n-TCgca28 MGI:MGI:4413795 +102467499 n-TCgca31 MGI:MGI:4413798 +102467500 n-TCgca33 MGI:MGI:4413800 +102467501 n-TCgca35 MGI:MGI:4413802 +102467502 n-TCgca38 MGI:MGI:4413805 +102467503 n-TCgca42 MGI:MGI:4413809 +102467504 n-TCgca43 MGI:MGI:4413810 +102467505 n-TCgca45 MGI:MGI:4413812 +102467506 n-TCgca47 MGI:MGI:4413814 +102467507 n-TCgca51 MGI:MGI:4413818 +102467508 n-TCgca53 MGI:MGI:4413820 +102467509 n-TCgca55 MGI:MGI:4413822 +102467510 n-TQctg1 MGI:MGI:4413825 +102467511 n-TQctg3 MGI:MGI:4413827 +102467512 n-TQctg6 MGI:MGI:4413830 +102467514 n-TQttg1 MGI:MGI:4413835 +102467515 n-TQttg3 MGI:MGI:4413837 +102467516 n-TQttg5 MGI:MGI:4413839 +102467517 n-TEctc1 MGI:MGI:4413841 +102467518 n-TEctc4 MGI:MGI:4413844 +102467519 n-TEctc6 MGI:MGI:4413846 +102467520 n-TEctc8 MGI:MGI:4413848 +102467521 n-TEctc11 MGI:MGI:4413851 +102467522 n-TEctc12 MGI:MGI:4413852 +102467523 n-TEttc2 MGI:MGI:4413855 +102467524 n-TEttc4 MGI:MGI:4413857 +102467525 n-TEttc6 MGI:MGI:4413859 +102467526 n-TGacc1 MGI:MGI:4413862 +102467527 n-TGccc3 MGI:MGI:4413864 +102467528 n-TGccc5 MGI:MGI:4413866 +102467529 n-TGccc7 MGI:MGI:4413868 +102467530 n-TGgcc2 MGI:MGI:4413871 +102467531 n-TGgcc5 MGI:MGI:4413874 +102467532 n-TGgcc8 MGI:MGI:4413877 +102467533 n-TGgcc11 MGI:MGI:4413880 +102467534 n-TGgcc13 MGI:MGI:4413882 +102467535 n-TGtcc1 MGI:MGI:4413884 +102467536 n-TGtcc3 MGI:MGI:4413886 +102467537 n-TGtcc6 MGI:MGI:4413889 +102467538 n-THatg1 MGI:MGI:4413891 +102467539 n-THgtg6 MGI:MGI:4413896 +102467541 n-TIaat2 MGI:MGI:4413903 +102467542 n-TIaat3 MGI:MGI:4413904 +102467543 n-TIaat5 MGI:MGI:4413906 +102467544 n-TIaat7 MGI:MGI:4413908 +102467546 n-TIaat12 MGI:MGI:4413913 +102467548 n-TIaat16 MGI:MGI:4413917 +102467549 n-TLaag2 MGI:MGI:4413920 +102467550 n-TLaag5 MGI:MGI:4413923 +102467551 n-TLaag8 MGI:MGI:4413926 +102467552 n-TLcaa1 MGI:MGI:4413928 +102467553 n-TLcag1 MGI:MGI:4413931 +102467554 n-TLcag3 MGI:MGI:4413933 +102467555 n-TLcag5 MGI:MGI:4413935 +102467556 n-TLcag8 MGI:MGI:4413938 +102467557 n-TLcag10 MGI:MGI:4413940 +102467559 n-TLtag1 MGI:MGI:4413945 +102467560 n-TKctt1 MGI:MGI:4413948 +102467561 n-TKctt2 MGI:MGI:4413949 +102467562 n-TKctt5 MGI:MGI:4413952 +102467563 n-TKctt7 MGI:MGI:4413954 +102467564 n-TKctt10 MGI:MGI:4413957 +102467565 n-TKctt12 MGI:MGI:4413959 +102467566 n-TKctt14 MGI:MGI:4413961 +102467567 n-TKctt16 MGI:MGI:4413963 +102467568 n-TKctt19 MGI:MGI:4413966 +102467570 n-TKctt24 MGI:MGI:4413971 +102467571 n-TKctt27 MGI:MGI:4413974 +102467572 n-TKctt29 MGI:MGI:4413976 +102467573 n-TMcat1 MGI:MGI:4413978 +102467575 n-TMcat6 MGI:MGI:4413983 +102467578 n-TMcat13 MGI:MGI:4413990 +102467579 n-TMcat16 MGI:MGI:4413993 +102467580 n-TMcat18 MGI:MGI:4413995 +102467582 n-TFgaa3 MGI:MGI:4413998 +102467583 n-TFgaa6 MGI:MGI:4414001 +102467584 n-TPagg1 MGI:MGI:4414003 +102467585 n-TPagg4 MGI:MGI:4414006 +102467586 n-TPagg6 MGI:MGI:4414008 +102467587 n-TPcgg3 MGI:MGI:4414011 +102467588 n-TPtgg2 MGI:MGI:4414014 +102467589 n-TPtgg4 MGI:MGI:4414016 +102467590 n-TPtgg6 MGI:MGI:4414018 +102467591 n-TUtca1 MGI:MGI:4414021 +102467592 n-TSaga4 MGI:MGI:4414024 +102467595 n-TSaga2 MGI:MGI:4414031 +102467596 n-TScga2 MGI:MGI:4414033 +102467597 n-TSgct2 MGI:MGI:4414036 +102467598 n-TSgct7 MGI:MGI:4414041 +102467599 n-TSgga1 MGI:MGI:4414043 +102467600 n-TStga3 MGI:MGI:4414046 +102467601 n-TTagt1 MGI:MGI:4414048 +102467602 n-TTagt3 MGI:MGI:4414050 +102467603 n-TTagt5 MGI:MGI:4414052 +102467604 n-TTagt7 MGI:MGI:4414054 +102467605 n-TTcgt1 MGI:MGI:4414057 +102467606 n-TTcgt4 MGI:MGI:4414060 +102467607 n-TTtgt1 MGI:MGI:4414062 +102467608 n-TTtgt4 MGI:MGI:4414065 +102467609 n-TWcca2 MGI:MGI:4414067 +102467610 n-TWcca4 MGI:MGI:4414069 +102467611 n-TWcca6 MGI:MGI:4414071 +102467612 n-TWcca8 MGI:MGI:4414073 +102467613 n-TYgta3 MGI:MGI:4414076 +102467614 n-TYgta5 MGI:MGI:4414078 +102467615 n-TYgta8 MGI:MGI:4414081 +102467616 n-TYgta10 MGI:MGI:4414083 +102467617 n-TVaac3 MGI:MGI:4414086 +102467618 n-TVaac5 MGI:MGI:4414088 +102467619 n-TVaac7 MGI:MGI:4414090 +102467620 n-TVcac1 MGI:MGI:4414092 +102467623 n-TVcac7 MGI:MGI:4414098 +102467624 n-TVcac9 MGI:MGI:4414100 +102467625 n-TVcac11 MGI:MGI:4414102 +102467626 n-TVtac1 MGI:MGI:4414104 +102467627 n-TVtac3 MGI:MGI:4414106 +102467628 n-TRacg1 MGI:MGI:4413714 +102467629 n-TDgtc8 MGI:MGI:4413759 +102467630 n-TCgca37 MGI:MGI:4413804 +102467631 n-TEctc10 MGI:MGI:4413850 +102467632 n-TLtaa4 MGI:MGI:4413944 +102467633 n-TMcat12 MGI:MGI:4413989 +102467634 n-TSgct1 MGI:MGI:4414035 +102467635 n-TAagc7 MGI:MGI:4413680 +102467636 n-TAcgc6 MGI:MGI:4413698 +102467637 n-TRacg3 MGI:MGI:4413716 +102467638 n-TRtct5 MGI:MGI:4413733 +102467640 n-TCgca3 MGI:MGI:4413770 +102467641 n-TCgca21 MGI:MGI:4413788 +102467642 n-TCgca39 MGI:MGI:4413806 +102467643 n-TCgca57 MGI:MGI:4413824 +102467644 n-TEctc3 MGI:MGI:4413843 +102467646 n-TGgcc10 MGI:MGI:4413879 +102467647 n-TIaat1 MGI:MGI:4413902 +102467648 n-TLaag1 MGI:MGI:4413919 +102467649 n-TLcag7 MGI:MGI:4413937 +102467650 n-TKctt8 MGI:MGI:4413955 +102467651 n-TKctt26 MGI:MGI:4413973 +102467652 n-TMcat15 MGI:MGI:4413992 +102467653 n-TPcgg2 MGI:MGI:4414010 +102577427 Esp5 MGI:MGI:5522708 +102577428 Gm44501 MGI:MGI:5529083|Ensembl:ENSMUSG00000090897 +102631495 Gm16326 MGI:MGI:3840124 +102631496 Gm11528 MGI:MGI:3649788 +102631497 Gm29820 MGI:MGI:5588979 +102631498 Gm29821 MGI:MGI:5588980 +102631499 Gm29822 MGI:MGI:5588981 +102631500 Gm29823 MGI:MGI:5588982 +102631501 Gm29824 MGI:MGI:5588983 +102631502 Rpl15-ps4 MGI:MGI:3650246 +102631503 Gm29825 MGI:MGI:5588984 +102631504 Gm29826 MGI:MGI:5588985 +102631506 Gm29828 MGI:MGI:5588987 +102631507 Gm29829 MGI:MGI:5588988 +102631509 Gm13307 MGI:MGI:3701135 +102631510 Gm29830 MGI:MGI:5588989 +102631511 Gm29831 MGI:MGI:5588990 +102631512 Gm29832 MGI:MGI:5588991 +102631513 Gm11998 MGI:MGI:3650897 +102631515 Gm29834 MGI:MGI:5588993 +102631516 Gm29835 MGI:MGI:5588994 +102631517 Gm29836 MGI:MGI:5588995 +102631518 Gm38438 MGI:MGI:5621323 +102631520 Gm29838 MGI:MGI:5588997 +102631521 Gm29839 MGI:MGI:5588998 +102631522 Gm29120 MGI:MGI:5579826 +102631524 Gm21728 MGI:MGI:5433892 +102631526 Gm29842 MGI:MGI:5589001 +102631528 Gm29843 MGI:MGI:5589002 +102631529 Gm29844 MGI:MGI:5589003 +102631530 Gm21762 MGI:MGI:5433926 +102631532 Gm29845 MGI:MGI:5589004 +102631533 Gm29846 MGI:MGI:5589005 +102631534 Gm29847 MGI:MGI:5589006 +102631535 Gm29848 MGI:MGI:5589007 +102631538 Gm29850 MGI:MGI:5589009 +102631539 Gm29851 MGI:MGI:5589010 +102631540 Gm29852 MGI:MGI:5589011 +102631541 Gm29853 MGI:MGI:5589012 +102631542 Gm29854 MGI:MGI:5589013 +102631543 Gm15651 MGI:MGI:3783095 +102631544 Gm29855 MGI:MGI:5589014 +102631545 Gm29856 MGI:MGI:5589015 +102631546 Gm29857 MGI:MGI:5589016 +102631547 LOC102631547 - +102631548 Gm29858 MGI:MGI:5589017 +102631549 Gm29859 MGI:MGI:5589018 +102631550 Gm29860 MGI:MGI:5589019 +102631551 Gm26676 MGI:MGI:5477170 +102631552 Gm29861 MGI:MGI:5589020 +102631553 Gm29862 MGI:MGI:5589021 +102631554 Gm29863 MGI:MGI:5589022 +102631555 LOC102631555 - +102631556 Gm28075 MGI:MGI:5578781 +102631557 Gm29864 MGI:MGI:5589023 +102631558 Gm29865 MGI:MGI:5589024 +102631559 Gm29866 MGI:MGI:5589025 +102631560 Gm26973 MGI:MGI:5504088 +102631562 Gm29868 MGI:MGI:5589027 +102631563 Gm21851 MGI:MGI:5434015 +102631564 Gm28889 MGI:MGI:5579595 +102631566 Gm29870 MGI:MGI:5589029 +102631567 Gm17188 MGI:MGI:4938015 +102631568 Gm29871 MGI:MGI:5589030 +102631569 Gm29872 MGI:MGI:5589031 +102631570 Gm29873 MGI:MGI:5589032 +102631571 Gm29874 MGI:MGI:5589033 +102631572 Gm11685 MGI:MGI:3651603 +102631575 Gm29878 MGI:MGI:5589037 +102631576 Gm29879 MGI:MGI:5589038 +102631577 Gm29880 MGI:MGI:5589039 +102631578 Gm29881 MGI:MGI:5589040 +102631579 Gm26752 MGI:MGI:5477246 +102631580 Gm29882 MGI:MGI:5589041 +102631581 Gm29883 MGI:MGI:5589042 +102631582 Gm29884 MGI:MGI:5589043 +102631583 Gm13714 MGI:MGI:3650276 +102631584 Gm29885 MGI:MGI:5589044 +102631585 LOC102631585 - +102631586 Gm29886 MGI:MGI:5589045 +102631587 Gm29887 MGI:MGI:5589046 +102631588 Gm16068 MGI:MGI:3802005 +102631589 Gm10479 MGI:MGI:3704385 +102631590 Gm29888 MGI:MGI:5589047 +102631591 Gm29889 MGI:MGI:5589048 +102631592 Gm15230 MGI:MGI:3705131 +102631593 Gm29890 MGI:MGI:5589049 +102631594 Gm29891 MGI:MGI:5589050 +102631595 Gm29892 MGI:MGI:5589051 +102631596 Gm29893 MGI:MGI:5589052 +102631598 Gm29895 MGI:MGI:5589054 +102631599 Gm29896 MGI:MGI:5589055 +102631600 Gm29897 MGI:MGI:5589056 +102631601 Gm29898 MGI:MGI:5589057 +102631602 Gm29899 MGI:MGI:5589058 +102631604 Gm29901 MGI:MGI:5589060 +102631606 Gm29903 MGI:MGI:5589062 +102631607 Gm29904 MGI:MGI:5589063 +102631608 Gm29905 MGI:MGI:5589064 +102631609 Gm29906 MGI:MGI:5589065 +102631610 Gm29907 MGI:MGI:5589066 +102631611 Gm29908 MGI:MGI:5589067 +102631612 LOC102631612 - +102631613 Gm29909 MGI:MGI:5589068|Ensembl:ENSMUSG00000110988 +102631614 Gm29910 MGI:MGI:5589069 +102631615 Gm29911 MGI:MGI:5589070 +102631616 Gm14642 MGI:MGI:3705301|Ensembl:ENSMUSG00000086114 +102631617 Gm29912 MGI:MGI:5589071 +102631618 Gm29913 MGI:MGI:5589072 +102631619 Gm29914 MGI:MGI:5589073 +102631620 Gm29915 MGI:MGI:5589074 +102631621 Gm29916 MGI:MGI:5589075 +102631622 Gm29917 MGI:MGI:5589076 +102631623 Gm29918 MGI:MGI:5589077 +102631624 Gm29919 MGI:MGI:5589078 +102631625 Gm29920 MGI:MGI:5589079 +102631626 Gm29921 MGI:MGI:5589080 +102631627 Gm29922 MGI:MGI:5589081 +102631628 Gm29494 MGI:MGI:5580200 +102631629 Gm21843 MGI:MGI:5434007 +102631631 Gm28125 MGI:MGI:5578831 +102631632 Gm29924 MGI:MGI:5589083 +102631634 Gm29926 MGI:MGI:5589085 +102631635 Gm29927 MGI:MGI:5589086 +102631637 Gm29928 MGI:MGI:5589087 +102631639 Gm17078 MGI:MGI:4937905 +102631640 Gm29930 MGI:MGI:5589089 +102631641 LOC102631641 - +102631643 Gm12203 MGI:MGI:3650182 +102631644 Gm29931 MGI:MGI:5589090 +102631645 Gm29932 MGI:MGI:5589091 +102631646 Gm29933 MGI:MGI:5589092 +102631647 Gm16041 MGI:MGI:3801909 +102631649 Gm29935 MGI:MGI:5589094 +102631650 Gm29936 MGI:MGI:5589095 +102631652 Gm29415 MGI:MGI:5580121 +102631653 LOC102631653 - +102631654 Gm29938 MGI:MGI:5589097 +102631656 Gm29940 MGI:MGI:5589099 +102631657 Gm29941 MGI:MGI:5589100 +102631658 Gm14437 MGI:MGI:3652089 +102631659 Gm29942 MGI:MGI:5589101 +102631660 Gm29943 MGI:MGI:5589102 +102631661 Gm29944 MGI:MGI:5589103 +102631662 Gm29945 MGI:MGI:5589104 +102631663 Gm29946 MGI:MGI:5589105 +102631664 Gm29947 MGI:MGI:5589106 +102631665 Gm29948 MGI:MGI:5589107 +102631666 Gm29949 MGI:MGI:5589108 +102631667 Gm29950 MGI:MGI:5589109 +102631669 Gm29952 MGI:MGI:5589111 +102631670 LOC102631670 - +102631671 Gm21819 MGI:MGI:5433983 +102631672 Gm28165 MGI:MGI:5578871 +102631673 Gm29567 MGI:MGI:5580273 +102631674 Gm28913 MGI:MGI:5579619 +102631675 Gm29954 MGI:MGI:5589113 +102631676 LOC102631676 - +102631677 Gm29955 MGI:MGI:5589114 +102631679 LOC102631679 - +102631680 Gm29957 MGI:MGI:5589116 +102631681 Gm29958 MGI:MGI:5589117 +102631682 Gm11683 MGI:MGI:3651846|Ensembl:ENSMUSG00000087139 +102631683 Gm29959 MGI:MGI:5589118 +102631684 Gm29960 MGI:MGI:5589119 +102631685 Gm29642 MGI:MGI:5580348 +102631686 Gm29961 MGI:MGI:5589120|Ensembl:ENSMUSG00000111400 +102631687 Gm29962 MGI:MGI:5589121 +102631690 Gm29964 MGI:MGI:5589123 +102631691 LOC102631691 - +102631692 Gm29965 MGI:MGI:5589124 +102631693 Gm29966 MGI:MGI:5589125 +102631694 Gm29967 MGI:MGI:5589126 +102631696 Gm29968 MGI:MGI:5589127|Ensembl:ENSMUSG00000113813 +102631697 Gm14664 MGI:MGI:3705306 +102631700 Gm29377 MGI:MGI:5580083 +102631702 Gm29972 MGI:MGI:5589131 +102631704 Gm29974 MGI:MGI:5589133 +102631705 Gm29975 MGI:MGI:5589134 +102631706 Gm29976 MGI:MGI:5589135 +102631707 Gm29977 MGI:MGI:5589136 +102631708 Gm29978 MGI:MGI:5589137 +102631709 Gm29979 MGI:MGI:5589138 +102631711 Gm29981 MGI:MGI:5589140 +102631712 Gm29982 MGI:MGI:5589141 +102631713 Gm29983 MGI:MGI:5589142 +102631714 Gm29984 MGI:MGI:5589143 +102631715 Gm29985 MGI:MGI:5589144 +102631717 Gm29986 MGI:MGI:5589145 +102631718 Gm29987 MGI:MGI:5589146 +102631723 Gm29992 MGI:MGI:5589151 +102631724 Gm29993 MGI:MGI:5589152 +102631725 Gm29994 MGI:MGI:5589153 +102631726 LOC102631726 - +102631727 Gm29995 MGI:MGI:5589154 +102631728 Gm29996 MGI:MGI:5589155 +102631729 Gm29997 MGI:MGI:5589156 +102631730 4930512M02Rik MGI:MGI:1922360|Ensembl:ENSMUSG00000062511|Vega:OTTMUSG00000005158 +102631731 Gm29998 MGI:MGI:5589157 +102631733 Gm29999 MGI:MGI:5589158|Ensembl:ENSMUSG00000102629 +102631734 Gm30000 MGI:MGI:5589159 +102631735 LOC102631735 - +102631736 Gm30001 MGI:MGI:5589160 +102631737 Gm29495 MGI:MGI:5580201 +102631738 Gm30002 MGI:MGI:5589161 +102631739 Gm30003 MGI:MGI:5589162|Ensembl:ENSMUSG00000107318 +102631741 Gm30005 MGI:MGI:5589164 +102631742 Gm30006 MGI:MGI:5589165 +102631744 Gm17174 MGI:MGI:4938001 +102631745 Gm30008 MGI:MGI:5589167 +102631746 Gm30009 MGI:MGI:5589168 +102631747 Gm30010 MGI:MGI:5589169 +102631749 LOC102631749 - +102631750 Gm30011 MGI:MGI:5589170 +102631751 Gm30012 MGI:MGI:5589171 +102631753 Gm30013 MGI:MGI:5589172 +102631755 Gm30015 MGI:MGI:5589174 +102631756 Gm30016 MGI:MGI:5589175 +102631757 LOC102631757 Ensembl:ENSMUSG00000086010 +102631758 Gm11870 MGI:MGI:3650285 +102631760 Gm30017 MGI:MGI:5589176 +102631761 Gm30018 MGI:MGI:5589177 +102631762 Gm30019 MGI:MGI:5589178 +102631763 Gm30020 MGI:MGI:5589179 +102631766 Gm30021 MGI:MGI:5589180 +102631767 Gm38439 MGI:MGI:5621324 +102631768 Gm30022 MGI:MGI:5589181 +102631769 Gm30023 MGI:MGI:5589182 +102631771 Gm29089 MGI:MGI:5579795|Ensembl:ENSMUSG00000101492 +102631772 Gm30025 MGI:MGI:5589184 +102631773 Gm29466 MGI:MGI:5580172 +102631774 Gm30026 MGI:MGI:5589185 +102631775 Gm21198 MGI:MGI:5434553 +102631776 Gm30027 MGI:MGI:5589186 +102631777 Gm30028 MGI:MGI:5589187 +102631779 Gm15581 MGI:MGI:3783029 +102631780 LOC102631780 Ensembl:ENSMUSG00000097233 +102631782 Gm30031 MGI:MGI:5589190 +102631783 Gm30032 MGI:MGI:5589191 +102631784 Gm13267 MGI:MGI:3652179 +102631785 Gm30033 MGI:MGI:5589192 +102631786 Gm30034 MGI:MGI:5589193 +102631787 Gm30035 MGI:MGI:5589194 +102631788 Gm30036 MGI:MGI:5589195 +102631791 Gm11465 MGI:MGI:3649368 +102631793 Gm30039 MGI:MGI:5589198 +102631794 Gm30040 MGI:MGI:5589199 +102631795 Gm30041 MGI:MGI:5589200 +102631796 Gm30042 MGI:MGI:5589201 +102631797 Gm30043 MGI:MGI:5589202 +102631798 Gm30044 MGI:MGI:5589203 +102631799 Gm30045 MGI:MGI:5589204 +102631801 Gm30047 MGI:MGI:5589206 +102631802 Gm30048 MGI:MGI:5589207 +102631804 Gm28671 MGI:MGI:5579377 +102631805 LOC102631805 - +102631806 Gm38440 MGI:MGI:5621325 +102631807 Gm30049 MGI:MGI:5589208 +102631808 Gm30050 MGI:MGI:5589209 +102631810 Gm30052 MGI:MGI:5589211|Ensembl:ENSMUSG00000110582 +102631812 Gm30054 MGI:MGI:5589213 +102631813 Gm30055 MGI:MGI:5589214 +102631815 Gm30056 MGI:MGI:5589215 +102631816 Gm30057 MGI:MGI:5589216 +102631817 Gm30058 MGI:MGI:5589217 +102631818 Gm30059 MGI:MGI:5589218 +102631819 Gm30060 MGI:MGI:5589219 +102631820 Gm30061 MGI:MGI:5589220 +102631821 Gm11682 MGI:MGI:3651410 +102631822 Gm30062 MGI:MGI:5589221 +102631823 Gm30063 MGI:MGI:5589222 +102631824 Gm30064 MGI:MGI:5589223 +102631827 Gm30066 MGI:MGI:5589225 +102631828 Gm30067 MGI:MGI:5589226 +102631829 Gm30068 MGI:MGI:5589227 +102631830 Gm29418 MGI:MGI:5580124 +102631832 Gm30069 MGI:MGI:5589228 +102631833 Gm14040 MGI:MGI:3651082 +102631836 Atp5k-ps2 MGI:MGI:107356 +102631839 Gm30073 MGI:MGI:5589232 +102631840 Gm11999 MGI:MGI:3650903 +102631841 Gm26629 MGI:MGI:5477123 +102631842 Gm28077 MGI:MGI:5578783 +102631843 Gm30074 MGI:MGI:5589233 +102631845 Gm30075 MGI:MGI:5589234 +102631846 Gm30076 MGI:MGI:5589235 +102631847 Gm28260 MGI:MGI:5578966|Ensembl:ENSMUSG00000099799 +102631848 Gm28371 MGI:MGI:5579077 +102631850 Gm26927 MGI:MGI:5504042 +102631851 Gm30078 MGI:MGI:5589237 +102631852 Gm30079 MGI:MGI:5589238 +102631854 Gm30081 MGI:MGI:5589240 +102631855 Gm30082 MGI:MGI:5589241 +102631856 Gm30083 MGI:MGI:5589242 +102631857 Gm27017 MGI:MGI:5504132 +102631858 Gm30084 MGI:MGI:5589243 +102631859 Gm30085 MGI:MGI:5589244 +102631860 Gm30086 MGI:MGI:5589245 +102631862 Gm30088 MGI:MGI:5589247 +102631863 Gm30089 MGI:MGI:5589248 +102631864 Gm30090 MGI:MGI:5589249 +102631865 Gm30091 MGI:MGI:5589250 +102631866 Gm30092 MGI:MGI:5589251 +102631868 Gm13912 MGI:MGI:3650993|Ensembl:ENSMUSG00000086758 +102631869 Gm30093 MGI:MGI:5589252 +102631870 Gm30094 MGI:MGI:5589253 +102631871 Gm30095 MGI:MGI:5589254 +102631873 Gm30097 MGI:MGI:5589256 +102631874 Gm20627 MGI:MGI:5313074 +102631879 Gm30101 MGI:MGI:5589260 +102631880 Gm30102 MGI:MGI:5589261 +102631881 Gm30103 MGI:MGI:5589262 +102631882 Gm28795 MGI:MGI:5579501 +102631883 Gm30104 MGI:MGI:5589263 +102631885 Gm30106 MGI:MGI:5589265 +102631886 Gm30107 MGI:MGI:5589266 +102631887 Gm30108 MGI:MGI:5589267 +102631889 Gm16638 MGI:MGI:4439562 +102631890 Gm30110 MGI:MGI:5589269 +102631892 Gm30112 MGI:MGI:5589271 +102631893 LOC102631893 - +102631894 Gm30113 MGI:MGI:5589272 +102631896 Gm30115 MGI:MGI:5589274 +102631897 Astx1c MGI:MGI:3705323 +102631898 Gm30116 MGI:MGI:5589275 +102631899 Gm30117 MGI:MGI:5589276 +102631900 Gm30118 MGI:MGI:5589277 +102631901 Gm14041 MGI:MGI:3651081 +102631902 Gm30119 MGI:MGI:5589278 +102631903 Gm30120 MGI:MGI:5589279 +102631904 Gm30121 MGI:MGI:5589280 +102631905 Gm30122 MGI:MGI:5589281|Ensembl:ENSMUSG00000112433 +102631907 Gm30123 MGI:MGI:5589282 +102631908 Gm15030 MGI:MGI:3705338 +102631909 Gm30124 MGI:MGI:5589283 +102631910 Gm30125 MGI:MGI:5589284 +102631911 Gm28296 MGI:MGI:5579002 +102631912 LOC102631912 - +102631913 Gm21795 MGI:MGI:5433959 +102631914 Gm30126 MGI:MGI:5589285 +102631915 Gm30127 MGI:MGI:5589286 +102631917 Gm29504 MGI:MGI:5580210|Ensembl:ENSMUSG00000100533 +102631918 Gm30129 MGI:MGI:5589288 +102631919 Gm21963 MGI:MGI:5439432 +102631920 Gm30130 MGI:MGI:5589289 +102631922 Gm30132 MGI:MGI:5589291 +102631924 LOC102631924 - +102631925 Gm12289 MGI:MGI:3649419 +102631926 Gm30134 MGI:MGI:5589293 +102631927 Gm30135 MGI:MGI:5589294 +102631928 Gm30136 MGI:MGI:5589295 +102631929 Gm30137 MGI:MGI:5589296 +102631930 LOC102631930 - +102631931 Gm30138 MGI:MGI:5589297 +102631932 Gm30139 MGI:MGI:5589298 +102631933 Gm30140 MGI:MGI:5589299 +102631935 Gm13923 MGI:MGI:3650170 +102631936 Gm30141 MGI:MGI:5589300 +102631937 Gm30142 MGI:MGI:5589301 +102631938 Gm30143 MGI:MGI:5589302 +102631939 Gm12977 MGI:MGI:3650699 +102631940 LOC102631940 - +102631941 Gm30144 MGI:MGI:5589303 +102631942 Gm30145 MGI:MGI:5589304 +102631943 LOC102631943 - +102631944 Gm30146 MGI:MGI:5589305 +102631945 Gm30147 MGI:MGI:5589306 +102631947 Gm14936 MGI:MGI:3705196|Ensembl:ENSMUSG00000084963 +102631948 Gm30149 MGI:MGI:5589308 +102631949 Gm30150 MGI:MGI:5589309 +102631950 Gm30151 MGI:MGI:5589310 +102631952 LOC102631952 - +102631953 Gm29565 MGI:MGI:5580271|Ensembl:ENSMUSG00000101060 +102631954 Gm30153 MGI:MGI:5589312 +102631955 Gm30154 MGI:MGI:5589313 +102631956 Gm30155 MGI:MGI:5589314 +102631958 Gm30157 MGI:MGI:5589316 +102631959 Gm30158 MGI:MGI:5589317 +102631960 Gm30159 MGI:MGI:5589318 +102631961 Gm26634 MGI:MGI:5477128 +102631962 Gm30160 MGI:MGI:5589319 +102631965 Gm26574 MGI:MGI:5477068 +102631966 Gm30162 MGI:MGI:5589321 +102631967 Gm30163 MGI:MGI:5589322 +102631968 Gm30164 MGI:MGI:5589323 +102631969 Gm30165 MGI:MGI:5589324 +102631970 Gm30166 MGI:MGI:5589325 +102631971 LOC102631971 - +102631973 Gm30168 MGI:MGI:5589327 +102631974 Gm30169 MGI:MGI:5589328 +102631976 Platr29 MGI:MGI:3650001 +102631977 LOC102631977 - +102631979 LOC102631979 - +102631980 Gm30172 MGI:MGI:5589331 +102631981 Gm30173 MGI:MGI:5589332 +102631982 LOC102631982 - +102631983 LOC102631983 - +102631984 Gm30174 MGI:MGI:5589333 +102631985 Gm30175 MGI:MGI:5589334 +102631986 Gm15524 MGI:MGI:3782971 +102631988 Gm29003 MGI:MGI:5579709 +102631989 Gm30177 MGI:MGI:5589336 +102631990 Gm21825 MGI:MGI:5433989 +102631991 Gm30178 MGI:MGI:5589337 +102631992 LOC102631992 - +102631993 LOC102631993 - +102631994 Gm30179 MGI:MGI:5589338 +102631995 LOC102631995 - +102631997 Gm12589 MGI:MGI:3650371|Ensembl:ENSMUSG00000085126 +102631998 Gm30181 MGI:MGI:5589340 +102631999 Gm30182 MGI:MGI:5589341 +102632001 Gm30184 MGI:MGI:5589343 +102632002 Gm30185 MGI:MGI:5589344 +102632003 Gm30186 MGI:MGI:5589345 +102632004 Gm30187 MGI:MGI:5589346 +102632006 LOC102632006 - +102632007 Gm30188 MGI:MGI:5589347 +102632008 Gm30189 MGI:MGI:5589348 +102632009 Gm30190 MGI:MGI:5589349 +102632010 Gm30191 MGI:MGI:5589350 +102632011 Gm30192 MGI:MGI:5589351 +102632012 Gm30193 MGI:MGI:5589352 +102632015 Gm30195 MGI:MGI:5589354 +102632016 LOC102632016 - +102632017 Gm30196 MGI:MGI:5589355 +102632019 Gm26777 MGI:MGI:5477271 +102632020 Gm30198 MGI:MGI:5589357 +102632021 Gm30199 MGI:MGI:5589358 +102632023 Gm28603 MGI:MGI:5579309 +102632027 Gm30204 MGI:MGI:5589363 +102632028 Gm30205 MGI:MGI:5589364 +102632029 Gm30206 MGI:MGI:5589365 +102632030 Gm16133 MGI:MGI:3802155 +102632031 LOC102632031 - +102632032 Gm30207 MGI:MGI:5589366 +102632033 Gm30208 MGI:MGI:5589367 +102632034 Gm30209 MGI:MGI:5589368 +102632035 Gm30210 MGI:MGI:5589369 +102632036 Gm30211 MGI:MGI:5589370 +102632037 Gm30212 MGI:MGI:5589371 +102632038 Gm30213 MGI:MGI:5589372 +102632039 Gm30214 MGI:MGI:5589373 +102632040 Gm30215 MGI:MGI:5589374 +102632041 Gm30216 MGI:MGI:5589375 +102632042 Gm30217 MGI:MGI:5589376 +102632044 Gm30219 MGI:MGI:5589378 +102632045 Gm30220 MGI:MGI:5589379 +102632047 Gm30222 MGI:MGI:5589381 +102632048 Gm30223 MGI:MGI:5589382 +102632049 Gm30224 MGI:MGI:5589383 +102632050 Gm38441 MGI:MGI:5621326 +102632051 Gm30225 MGI:MGI:5589384 +102632053 LOC102632053 - +102632055 Gm30228 MGI:MGI:5589387 +102632056 Gm30229 MGI:MGI:5589388 +102632057 Gm30230 MGI:MGI:5589389 +102632059 Gm30232 MGI:MGI:5589391 +102632060 Gm30233 MGI:MGI:5589392 +102632061 Gm30234 MGI:MGI:5589393 +102632062 Gm30235 MGI:MGI:5589394 +102632063 LOC102632063 - +102632064 Gm30236 MGI:MGI:5589395 +102632066 Gm30238 MGI:MGI:5589397 +102632067 Gm28749 MGI:MGI:5579455 +102632068 Gm30239 MGI:MGI:5589398 +102632069 Gm30240 MGI:MGI:5589399 +102632070 Gm20465 MGI:MGI:5141930 +102632071 Gm30241 MGI:MGI:5589400 +102632072 Gm30242 MGI:MGI:5589401 +102632073 Gm30243 MGI:MGI:5589402 +102632075 Gm30244 MGI:MGI:5589403 +102632076 Gm30245 MGI:MGI:5589404 +102632077 Gm30246 MGI:MGI:5589405 +102632078 Gm12290 MGI:MGI:3650700|Ensembl:ENSMUSG00000087622 +102632080 Gm30247 MGI:MGI:5589406 +102632081 Gm30248 MGI:MGI:5589407 +102632084 Gm30251 MGI:MGI:5589410 +102632085 Gm30252 MGI:MGI:5589411 +102632086 Gm13383 MGI:MGI:3650825 +102632087 Gm13373 MGI:MGI:3650390 +102632089 Gm30254 MGI:MGI:5589413 +102632090 Gm30255 MGI:MGI:5589414 +102632091 Gm30256 MGI:MGI:5589415 +102632092 Gm30257 MGI:MGI:5589416 +102632093 Gm30258 MGI:MGI:5589417 +102632094 Gm30259 MGI:MGI:5589418 +102632095 Gm22219 MGI:MGI:5451996 +102632096 Gm38442 MGI:MGI:5621327 +102632097 Gm30260 MGI:MGI:5589419 +102632098 Gm30261 MGI:MGI:5589420 +102632099 Gm30262 MGI:MGI:5589421 +102632100 Gm30263 MGI:MGI:5589422 +102632102 LOC102632102 - +102632105 Gm21821 MGI:MGI:5433985 +102632106 Gm30266 MGI:MGI:5589425 +102632107 Gm12897 MGI:MGI:3649906 +102632108 Gm30267 MGI:MGI:5589426 +102632110 Gm16061 MGI:MGI:3801920 +102632112 Gm30270 MGI:MGI:5589429 +102632113 LOC102632113 Ensembl:ENSMUSG00000096183|Vega:OTTMUSG00000035714 +102632114 Gm30271 MGI:MGI:5589430 +102632115 Gm30272 MGI:MGI:5589431 +102632116 Gm30273 MGI:MGI:5589432 +102632117 Gm30274 MGI:MGI:5589433 +102632118 Gm30275 MGI:MGI:5589434 +102632119 Gm16311 MGI:MGI:3826532 +102632120 Gm30276 MGI:MGI:5589435 +102632121 Gm30277 MGI:MGI:5589436 +102632124 Gm26901 MGI:MGI:5477395 +102632125 Gm30279 MGI:MGI:5589438 +102632126 Gm30280 MGI:MGI:5589439 +102632127 Gm30281 MGI:MGI:5589440 +102632128 Gm30282 MGI:MGI:5589441 +102632129 Gm30283 MGI:MGI:5589442 +102632130 Gm30284 MGI:MGI:5589443 +102632131 Gm30285 MGI:MGI:5589444 +102632132 Gm30286 MGI:MGI:5589445 +102632133 Gm30287 MGI:MGI:5589446 +102632134 Gm30288 MGI:MGI:5589447 +102632135 Gm30289 MGI:MGI:5589448 +102632136 Gm20482 MGI:MGI:5141947 +102632137 Gm30290 MGI:MGI:5589449 +102632138 Gm30291 MGI:MGI:5589450 +102632139 Gm30292 MGI:MGI:5589451|Ensembl:ENSMUSG00000104109 +102632140 Gm30293 MGI:MGI:5589452 +102632141 Gm30294 MGI:MGI:5589453 +102632142 LOC102632142 - +102632143 Gm30295 MGI:MGI:5589454 +102632144 Gm16246 MGI:MGI:3826570 +102632145 Gm21804 MGI:MGI:5433968 +102632146 Gm30296 MGI:MGI:5589455 +102632148 Gm30298 MGI:MGI:5589457 +102632151 Gm30301 MGI:MGI:5589460 +102632152 Gm30302 MGI:MGI:5589461|Ensembl:ENSMUSG00000114073 +102632153 Gm30303 MGI:MGI:5589462 +102632154 Gm26995 MGI:MGI:5504110 +102632155 Gm24105 MGI:MGI:5453882 +102632156 LOC102632156 - +102632158 Gm30305 MGI:MGI:5589464 +102632159 Gm30306 MGI:MGI:5589465 +102632160 Gm30307 MGI:MGI:5589466 +102632161 Gm30308 MGI:MGI:5589467 +102632162 Gm30309 MGI:MGI:5589468 +102632163 Gm30310 MGI:MGI:5589469 +102632164 Gm30311 MGI:MGI:5589470 +102632165 Gm13388 MGI:MGI:3649903 +102632166 Gm30312 MGI:MGI:5589471 +102632167 Gm30313 MGI:MGI:5589472 +102632168 Gm30314 MGI:MGI:5589473 +102632169 Gm30315 MGI:MGI:5589474 +102632170 Gm30316 MGI:MGI:5589475 +102632171 Gm30317 MGI:MGI:5589476 +102632172 Gm30318 MGI:MGI:5589477 +102632173 Gm13775 MGI:MGI:3712466 +102632174 Gm30319 MGI:MGI:5589478 +102632176 Gm30320 MGI:MGI:5589479 +102632177 Gm30321 MGI:MGI:5589480 +102632178 Gm30322 MGI:MGI:5589481 +102632179 Gm28347 MGI:MGI:5579053 +102632180 LOC102632180 - +102632183 Gm21865 MGI:MGI:5434029 +102632184 Gm30325 MGI:MGI:5589484 +102632185 Gm21808 MGI:MGI:5433972 +102632187 Gm30327 MGI:MGI:5589486 +102632188 Gm30328 MGI:MGI:5589487 +102632189 Gm30329 MGI:MGI:5589488 +102632190 Gm30330 MGI:MGI:5589489 +102632191 Gm30331 MGI:MGI:5589490 +102632192 Gm30332 MGI:MGI:5589491|Ensembl:ENSMUSG00000107675 +102632193 Gm30333 MGI:MGI:5589492 +102632194 Gm30334 MGI:MGI:5589493 +102632195 Gm30335 MGI:MGI:5589494 +102632197 Gm30337 MGI:MGI:5589496 +102632198 Gm30338 MGI:MGI:5589497 +102632199 Gm30339 MGI:MGI:5589498 +102632200 Gm30340 MGI:MGI:5589499 +102632201 Gm30341 MGI:MGI:5589500 +102632202 Gm30342 MGI:MGI:5589501 +102632204 Gm30344 MGI:MGI:5589503 +102632205 Gm30345 MGI:MGI:5589504 +102632206 Gm30346 MGI:MGI:5589505 +102632207 Gm30347 MGI:MGI:5589506 +102632210 Gm30350 MGI:MGI:5589509 +102632211 Gm30351 MGI:MGI:5589510 +102632212 Gm30352 MGI:MGI:5589511 +102632213 Gm5548 MGI:MGI:3644344 +102632214 Gm30353 MGI:MGI:5589512 +102632215 Gm28295 MGI:MGI:5579001 +102632216 Gm30354 MGI:MGI:5589513 +102632217 Gm28697 MGI:MGI:5579403 +102632218 Gm30355 MGI:MGI:5589514 +102632222 Gm17182 MGI:MGI:4938009|Ensembl:ENSMUSG00000090642 +102632224 LOC102632224 - +102632225 Gm30360 MGI:MGI:5589519 +102632227 Gm30362 MGI:MGI:5589521 +102632228 Gm30363 MGI:MGI:5589522 +102632229 Gm30364 MGI:MGI:5589523 +102632230 Gm30365 MGI:MGI:5589524 +102632231 LOC102632231 - +102632232 Gm30366 MGI:MGI:5589525 +102632233 Gm30367 MGI:MGI:5589526 +102632234 Gm30368 MGI:MGI:5589527 +102632236 Gm30369 MGI:MGI:5589528 +102632237 Gm30370 MGI:MGI:5589529 +102632238 Gm30371 MGI:MGI:5589530 +102632240 Gm15555 MGI:MGI:3783004 +102632241 Gm30373 MGI:MGI:5589532 +102632242 Gm30374 MGI:MGI:5589533 +102632244 Gm30375 MGI:MGI:5589534 +102632246 Gm12354 MGI:MGI:3649534 +102632247 Gm30377 MGI:MGI:5589536 +102632248 Gm30378 MGI:MGI:5589537 +102632249 Gm11466 MGI:MGI:3650521 +102632251 Gm16143 MGI:MGI:3801780 +102632253 Gm30381 MGI:MGI:5589540 +102632254 Gm30382 MGI:MGI:5589541 +102632256 LOC102632256 - +102632257 Gm30384 MGI:MGI:5589543 +102632261 Gm21803 MGI:MGI:5433967 +102632262 Gm30388 MGI:MGI:5589547 +102632263 Gm30389 MGI:MGI:5589548 +102632265 Gm30391 MGI:MGI:5589550 +102632266 Gm30392 MGI:MGI:5589551 +102632268 Gm26974 MGI:MGI:5504089 +102632270 Gm30395 MGI:MGI:5589554 +102632272 Gm20717 MGI:MGI:5313164 +102632273 Gm29506 MGI:MGI:5580212 +102632274 Gm28818 MGI:MGI:5579524 +102632275 Gm30396 MGI:MGI:5589555 +102632276 Gm30397 MGI:MGI:5589556 +102632278 LOC102632278 - +102632279 Gm30398 MGI:MGI:5589557 +102632280 Mup-ps17 MGI:MGI:3705843 +102632283 Gm30399 MGI:MGI:5589558 +102632284 Gm30400 MGI:MGI:5589559 +102632285 Gm38443 MGI:MGI:5621328 +102632286 Gm30401 MGI:MGI:5589560 +102632287 Gm30402 MGI:MGI:5589561 +102632289 Gm30403 MGI:MGI:5589562 +102632290 Gm30404 MGI:MGI:5589563 +102632291 LOC102632291 - +102632292 LOC102632292 - +102632293 Gm30405 MGI:MGI:5589564 +102632296 Gm30408 MGI:MGI:5589567 +102632297 Gm30409 MGI:MGI:5589568 +102632299 Gm30411 MGI:MGI:5589570 +102632301 Gm30413 MGI:MGI:5589572 +102632302 LOC102632302 - +102632303 Gm30414 MGI:MGI:5589573 +102632304 Gm30415 MGI:MGI:5589574 +102632305 LOC102632305 - +102632307 Gm30416 MGI:MGI:5589575 +102632308 Gm30417 MGI:MGI:5589576 +102632310 Gm26626 MGI:MGI:5477120 +102632311 Gm30419 MGI:MGI:5589578 +102632312 Gm30420 MGI:MGI:5589579 +102632313 Gm30421 MGI:MGI:5589580 +102632315 Gm14232 MGI:MGI:3701956 +102632316 Gm21411 MGI:MGI:5434766 +102632317 Gm30422 MGI:MGI:5589581 +102632318 Gm30423 MGI:MGI:5589582 +102632319 LOC102632319 - +102632321 Gm15883 MGI:MGI:3801875 +102632323 Gm30426 MGI:MGI:5589585 +102632324 Gm30427 MGI:MGI:5589586 +102632325 Gm28356 MGI:MGI:5579062 +102632326 Gm21350 MGI:MGI:5434705 +102632328 Gm30429 MGI:MGI:5589588 +102632329 Gm28689 MGI:MGI:5579395 +102632331 Gm30431 MGI:MGI:5589590 +102632332 Gm16121 MGI:MGI:3802131 +102632333 Gm30432 MGI:MGI:5589591 +102632336 Gm30435 MGI:MGI:5589594 +102632338 Gm30437 MGI:MGI:5589596 +102632339 Gm30438 MGI:MGI:5589597 +102632340 Gm30439 MGI:MGI:5589598 +102632341 Gm30440 MGI:MGI:5589599 +102632344 Gm28876 MGI:MGI:5579582 +102632345 Gm30442 MGI:MGI:5589601 +102632346 Gm29040 MGI:MGI:5579746 +102632347 Gm30443 MGI:MGI:5589602 +102632348 Gm30444 MGI:MGI:5589603 +102632349 Gm30445 MGI:MGI:5589604 +102632350 Gm30446 MGI:MGI:5589605 +102632352 Gm28643 MGI:MGI:5579349 +102632353 Gm30447 MGI:MGI:5589606 +102632354 Gm30448 MGI:MGI:5589607 +102632355 Gm30449 MGI:MGI:5589608 +102632357 LOC102632357 - +102632358 Gm30451 MGI:MGI:5589610 +102632359 Gm30452 MGI:MGI:5589611 +102632360 Gm14616 MGI:MGI:3705280 +102632361 Gm30453 MGI:MGI:5589612 +102632362 Gm30454 MGI:MGI:5589613 +102632363 Gm30455 MGI:MGI:5589614 +102632364 Gm30456 MGI:MGI:5589615 +102632365 Gm30457 MGI:MGI:5589616 +102632366 Gm30458 MGI:MGI:5589617 +102632367 LOC102632367 - +102632369 Gm30459 MGI:MGI:5589618|Ensembl:ENSMUSG00000108468 +102632372 Gm30461 MGI:MGI:5589620 +102632375 Gm30464 MGI:MGI:5589623 +102632376 Gm30465 MGI:MGI:5589624 +102632377 Gm30466 MGI:MGI:5589625 +102632378 Gm30467 MGI:MGI:5589626 +102632380 Gm30469 MGI:MGI:5589628 +102632381 Gm30470 MGI:MGI:5589629 +102632382 LOC102632382 - +102632383 LOC102632383 - +102632384 Gm30471 MGI:MGI:5589630 +102632385 Gm30472 MGI:MGI:5589631 +102632386 Catspere2 MGI:MGI:5589632 +102632387 Gm30474 MGI:MGI:5589633 +102632388 Gm38444 MGI:MGI:5621329 +102632389 Gm24463 MGI:MGI:5454240 +102632390 Gm30475 MGI:MGI:5589634 +102632391 Gm30476 MGI:MGI:5589635 +102632393 Gm30478 MGI:MGI:5589637 +102632394 Gm26910 MGI:MGI:5477404 +102632396 Gm30480 MGI:MGI:5589639 +102632398 Gm30482 MGI:MGI:5589641 +102632399 Gm30483 MGI:MGI:5589642 +102632400 Gm26689 MGI:MGI:5477183 +102632401 Gm30484 MGI:MGI:5589643 +102632402 Gm38445 MGI:MGI:5621330 +102632403 Rpl17-ps8 MGI:MGI:3802129|Ensembl:ENSMUSG00000082035 +102632404 Gm15396 MGI:MGI:3705202|Ensembl:ENSMUSG00000109491 +102632407 Gm16570 MGI:MGI:4414990 +102632408 Gm30487 MGI:MGI:5589646 +102632410 Gm29002 MGI:MGI:5579708 +102632411 Gm30489 MGI:MGI:5589648 +102632412 Gm30490 MGI:MGI:5589649 +102632413 Gm30491 MGI:MGI:5589650 +102632414 Gm30492 MGI:MGI:5589651 +102632415 LOC102632415 - +102632417 Gm30493 MGI:MGI:5589652 +102632418 Gm30494 MGI:MGI:5589653 +102632420 Gm16118 MGI:MGI:3801926 +102632421 Gm30496 MGI:MGI:5589655 +102632423 Gm30498 MGI:MGI:5589657|Ensembl:ENSMUSG00000107933 +102632425 Gm30500 MGI:MGI:5589659 +102632426 Gm30501 MGI:MGI:5589660 +102632427 Gm30502 MGI:MGI:5589661 +102632429 Gm30504 MGI:MGI:5589663 +102632430 Gm30505 MGI:MGI:5589664 +102632431 Gm30506 MGI:MGI:5589665 +102632432 Gm30507 MGI:MGI:5589666 +102632434 Gm30509 MGI:MGI:5589668 +102632435 Gm30510 MGI:MGI:5589669 +102632436 Gm11872 MGI:MGI:3649333 +102632437 Gm30511 MGI:MGI:5589670 +102632438 Gm13709 MGI:MGI:3651118 +102632439 Snrpert MGI:MGI:3650419 +102632440 Gm30512 MGI:MGI:5589671 +102632441 Gm30513 MGI:MGI:5589672 +102632442 LOC102632442 - +102632444 Gm30515 MGI:MGI:5589674 +102632445 Gm30516 MGI:MGI:5589675 +102632446 Gm30517 MGI:MGI:5589676 +102632447 Gm28357 MGI:MGI:5579063|Ensembl:ENSMUSG00000100984 +102632448 Gm30518 MGI:MGI:5589677 +102632451 Gm30519 MGI:MGI:5589678 +102632452 Gm30520 MGI:MGI:5589679 +102632453 Gm29630 MGI:MGI:5580336 +102632454 Gm30521 MGI:MGI:5589680 +102632455 Gm30522 MGI:MGI:5589681 +102632456 Gm30523 MGI:MGI:5589682 +102632457 Gm30524 MGI:MGI:5589683 +102632458 Gm30525 MGI:MGI:5589684 +102632460 Gm30527 MGI:MGI:5589686 +102632461 Gm30528 MGI:MGI:5589687 +102632462 Gm30529 MGI:MGI:5589688 +102632463 LOC102632463 Ensembl:ENSMUSG00000079045 +102632464 Gm30530 MGI:MGI:5589689 +102632465 LOC102632465 - +102632466 Gm26962 MGI:MGI:5504077 +102632467 Gm30531 MGI:MGI:5589690 +102632468 Gm30532 MGI:MGI:5589691 +102632470 Gm30534 MGI:MGI:5589693 +102632472 Gm30536 MGI:MGI:5589695 +102632473 Gm30537 MGI:MGI:5589696 +102632474 Gm16225 MGI:MGI:3801903 +102632476 LOC102632476 - +102632477 Gm30539 MGI:MGI:5589698 +102632479 Gm30541 MGI:MGI:5589700 +102632481 Gm30543 MGI:MGI:5589702 +102632482 Gm30544 MGI:MGI:5589703 +102632483 Gm17330 MGI:MGI:4936964 +102632484 Gm26691 MGI:MGI:5477185 +102632488 Gm29508 MGI:MGI:5580214|Ensembl:ENSMUSG00000100789 +102632489 Gm30548 MGI:MGI:5589707 +102632490 Gm30549 MGI:MGI:5589708 +102632491 Gm30550 MGI:MGI:5589709 +102632492 Gm30551 MGI:MGI:5589710 +102632493 LOC102632493 - +102632494 Gm30552 MGI:MGI:5589711 +102632495 Gm30553 MGI:MGI:5589712 +102632496 Gm30554 MGI:MGI:5589713 +102632498 Gm30556 MGI:MGI:5589715 +102632499 Gm30557 MGI:MGI:5589716 +102632501 Gm30559 MGI:MGI:5589718 +102632502 Gm30560 MGI:MGI:5589719 +102632503 Gm30561 MGI:MGI:5589720 +102632504 LOC102632504 - +102632505 Gm30562 MGI:MGI:5589721 +102632506 Gm12591 MGI:MGI:3649887 +102632507 Gm30563 MGI:MGI:5589722 +102632508 Gm30564 MGI:MGI:5589723 +102632509 Gm30565 MGI:MGI:5589724 +102632511 Gm30567 MGI:MGI:5589726 +102632512 Gm30568 MGI:MGI:5589727 +102632513 Gm30569 MGI:MGI:5589728 +102632514 Gm13479 MGI:MGI:3651869 +102632515 Gm30570 MGI:MGI:5589729|Ensembl:ENSMUSG00000111266 +102632516 Gm30571 MGI:MGI:5589730 +102632517 Gm30572 MGI:MGI:5589731 +102632520 Gm30575 MGI:MGI:5589734 +102632522 Gm30577 MGI:MGI:5589736 +102632523 Gm29354 MGI:MGI:5580060 +102632525 Gm21842 MGI:MGI:5434006 +102632527 Gm28554 MGI:MGI:5579260 +102632530 Gm30581 MGI:MGI:5589740 +102632531 Gm30582 MGI:MGI:5589741 +102632532 Gm30583 MGI:MGI:5589742 +102632533 Gm30584 MGI:MGI:5589743 +102632534 Gm30585 MGI:MGI:5589744 +102632535 Gm30586 MGI:MGI:5589745 +102632536 Gm30587 MGI:MGI:5589746 +102632538 LOC102632538 - +102632539 Astx1b MGI:MGI:3705283 +102632540 Gm30588 MGI:MGI:5589747 +102632541 LOC102632541 - +102632542 Gm30589 MGI:MGI:5589748 +102632544 Gm30590 MGI:MGI:5589749 +102632545 Gm30591 MGI:MGI:5589750 +102632547 Gm12984 MGI:MGI:3651384 +102632548 Gm30593 MGI:MGI:5589752 +102632550 Gm30595 MGI:MGI:5589754 +102632551 Gm30596 MGI:MGI:5589755 +102632553 Gm30598 MGI:MGI:5589757 +102632554 Gm30599 MGI:MGI:5589758 +102632555 Gm12873 MGI:MGI:3651900 +102632556 Gm28185 MGI:MGI:5578891 +102632557 Gm28840 MGI:MGI:5579546 +102632558 Gm30600 MGI:MGI:5589759 +102632559 Gm30601 MGI:MGI:5589760 +102632560 Gm38446 MGI:MGI:5621331 +102632561 Gm30602 MGI:MGI:5589761 +102632562 Gm30603 MGI:MGI:5589762 +102632563 Gm30604 MGI:MGI:5589763 +102632566 Gm30605 MGI:MGI:5589764 +102632567 Gm30606 MGI:MGI:5589765 +102632568 Gm16116 MGI:MGI:3802040 +102632570 Gm30608 MGI:MGI:5589767 +102632571 Gm30609 MGI:MGI:5589768 +102632572 Gm30610 MGI:MGI:5589769 +102632573 Gm30611 MGI:MGI:5589770 +102632574 Gm30612 MGI:MGI:5589771 +102632575 Gm30613 MGI:MGI:5589772 +102632577 Gm30615 MGI:MGI:5589774 +102632579 Gm30617 MGI:MGI:5589776 +102632580 Gm30618 MGI:MGI:5589777 +102632581 Gm30619 MGI:MGI:5589778 +102632582 Gm30620 MGI:MGI:5589779 +102632584 Gm30622 MGI:MGI:5589781 +102632586 Gm30624 MGI:MGI:5589783 +102632587 Gm30625 MGI:MGI:5589784 +102632589 Gm26232 MGI:MGI:5456009 +102632590 Gm26851 MGI:MGI:5477345|Ensembl:ENSMUSG00000096978 +102632592 Gm29000 MGI:MGI:5579706 +102632593 Gm30627 MGI:MGI:5589786 +102632594 LOC102632594 - +102632595 Gm30628 MGI:MGI:5589787 +102632596 Gm30629 MGI:MGI:5589788 +102632597 Gm28523 MGI:MGI:5579229 +102632599 LOC102632599 - +102632600 Gm30631 MGI:MGI:5589790 +102632601 Gm30632 MGI:MGI:5589791 +102632602 Gm16553 MGI:MGI:4414973 +102632603 Gm30633 MGI:MGI:5589792 +102632604 Gm30634 MGI:MGI:5589793 +102632605 Gm30635 MGI:MGI:5589794 +102632606 Gm30636 MGI:MGI:5589795 +102632607 Gm30637 MGI:MGI:5589796 +102632608 Gm30638 MGI:MGI:5589797 +102632609 Gm30639 MGI:MGI:5589798 +102632610 Gm16254 MGI:MGI:3826579 +102632611 Gm11211 MGI:MGI:3651244 +102632612 Gm30640 MGI:MGI:5589799 +102632613 Gm14144 MGI:MGI:3702160 +102632614 Gm30641 MGI:MGI:5589800 +102632615 Gm30642 MGI:MGI:5589801 +102632617 Gm30644 MGI:MGI:5589803 +102632618 Gm30645 MGI:MGI:5589804 +102632619 Gm30646 MGI:MGI:5589805 +102632621 Gm30648 MGI:MGI:5589807 +102632622 LOC102632622 - +102632623 Gm30649 MGI:MGI:5589808 +102632626 Gm30652 MGI:MGI:5589811 +102632628 Gm30654 MGI:MGI:5589813 +102632629 Gm30655 MGI:MGI:5589814 +102632630 Gm30656 MGI:MGI:5589815 +102632631 Gm30657 MGI:MGI:5589816 +102632632 Gm30658 MGI:MGI:5589817 +102632634 Gm30660 MGI:MGI:5589819 +102632635 Gm26843 MGI:MGI:5477337 +102632637 Gm30661 MGI:MGI:5589820 +102632638 Gm26628 MGI:MGI:5477122 +102632639 Gm30662 MGI:MGI:5589821 +102632640 Gm30663 MGI:MGI:5589822 +102632641 Gm30664 MGI:MGI:5589823 +102632642 Lgals1-ps2 MGI:MGI:4938036 +102632643 Gm30665 MGI:MGI:5589824 +102632644 Gm30666 MGI:MGI:5589825 +102632645 Gm30667 MGI:MGI:5589826 +102632646 Gm30668 MGI:MGI:5589827 +102632649 Gm30671 MGI:MGI:5589830 +102632650 Gm30672 MGI:MGI:5589831 +102632651 Gm30673 MGI:MGI:5589832 +102632652 Gm30674 MGI:MGI:5589833 +102632653 Gm30675 MGI:MGI:5589834 +102632654 Gm16555 MGI:MGI:4414975 +102632655 Gm30676 MGI:MGI:5589835|Ensembl:ENSMUSG00000111778 +102632656 Gm30677 MGI:MGI:5589836 +102632657 Gm12678 MGI:MGI:3650923 +102632658 LOC102632658 - +102632659 Gm30678 MGI:MGI:5589837 +102632660 Gm30679 MGI:MGI:5589838 +102632661 Gm38447 MGI:MGI:5621332 +102632662 Gm30680 MGI:MGI:5589839 +102632663 Gm30681 MGI:MGI:5589840 +102632664 LOC102632664 - +102632665 Gm14344 MGI:MGI:3650758 +102632666 Gm30682 MGI:MGI:5589841 +102632668 Gm30684 MGI:MGI:5589843 +102632669 Gm16206 MGI:MGI:3801870|Ensembl:ENSMUSG00000085174 +102632671 Gm30686 MGI:MGI:5589845 +102632672 Gm30687 MGI:MGI:5589846 +102632673 Gm15245 MGI:MGI:3705110|Ensembl:ENSMUSG00000087587 +102632675 Gm29215 MGI:MGI:5579921|Ensembl:ENSMUSG00000099786 +102632676 Gm28738 MGI:MGI:5579444 +102632677 Gm29545 MGI:MGI:5580251 +102632679 Gm30688 MGI:MGI:5589847 +102632680 Gm30689 MGI:MGI:5589848 +102632681 Gm30690 MGI:MGI:5589849 +102632682 Gm38448 MGI:MGI:5621333 +102632683 Gm30691 MGI:MGI:5589850 +102632684 Gm30692 MGI:MGI:5589851 +102632685 Gm29155 MGI:MGI:5579861 +102632686 Gm16351 MGI:MGI:3840153 +102632687 Gm30693 MGI:MGI:5589852 +102632688 Gm30694 MGI:MGI:5589853 +102632689 Gm30695 MGI:MGI:5589854 +102632690 LOC102632690 - +102632691 Gm30696 MGI:MGI:5589855 +102632692 Gm30697 MGI:MGI:5589856 +102632693 Gm30698 MGI:MGI:5589857 +102632694 Gm30699 MGI:MGI:5589858 +102632697 Gm30700 MGI:MGI:5589859 +102632698 Gm30701 MGI:MGI:5589860 +102632699 Gm30702 MGI:MGI:5589861 +102632700 Gm28881 MGI:MGI:5579587|Ensembl:ENSMUSG00000100528 +102632703 Gm30704 MGI:MGI:5589863 +102632704 Gm14877 MGI:MGI:3708097 +102632705 Gm21854 MGI:MGI:5434018 +102632706 Gm30705 MGI:MGI:5589864 +102632707 Gm30706 MGI:MGI:5589865 +102632708 Gm15523 MGI:MGI:3782970 +102632709 Gm30707 MGI:MGI:5589866 +102632710 Gm30708 MGI:MGI:5589867 +102632711 Gm7284 MGI:MGI:3647125 +102632712 Gm30709 MGI:MGI:5589868|Ensembl:ENSMUSG00000113453 +102632714 Gm38449 MGI:MGI:5621334 +102632716 Gm30712 MGI:MGI:5589871 +102632717 Gm30713 MGI:MGI:5589872 +102632718 Gm30714 MGI:MGI:5589873 +102632720 Gm30716 MGI:MGI:5589875 +102632721 Gm30717 MGI:MGI:5589876 +102632722 Gm30718 MGI:MGI:5589877 +102632723 Gm30719 MGI:MGI:5589878 +102632724 Gm30720 MGI:MGI:5589879 +102632726 Gm30722 MGI:MGI:5589881 +102632727 Gm30723 MGI:MGI:5589882 +102632728 Gm30724 MGI:MGI:5589883 +102632729 Gm30725 MGI:MGI:5589884 +102632730 Gm30726 MGI:MGI:5589885 +102632732 Gm30728 MGI:MGI:5589887 +102632733 Gm30729 MGI:MGI:5589888 +102632734 Gm30730 MGI:MGI:5589889 +102632736 Gm13964 MGI:MGI:3649451 +102632737 Gm30732 MGI:MGI:5589891 +102632738 Gm30733 MGI:MGI:5589892 +102632739 LOC102632739 - +102632740 Gm30734 MGI:MGI:5589893 +102632741 Gm14342 MGI:MGI:3650757 +102632742 Scgb2b4-ps MGI:MGI:5578756 +102632743 Gm30735 MGI:MGI:5589894 +102632745 Gm30737 MGI:MGI:5589896|Ensembl:ENSMUSG00000104191|Vega:OTTMUSG00000050510 +102632746 Gm30738 MGI:MGI:5589897 +102632749 Gm21801 MGI:MGI:5433965 +102632750 Gm28234 MGI:MGI:5578940 +102632753 Gm29617 MGI:MGI:5580323 +102632755 Gm30744 MGI:MGI:5589903 +102632756 Gm30745 MGI:MGI:5589904 +102632757 Gm30746 MGI:MGI:5589905 +102632758 Gm30747 MGI:MGI:5589906 +102632759 Gm30748 MGI:MGI:5589907 +102632760 Gm30749 MGI:MGI:5589908 +102632761 LOC102632761 - +102632763 Gm30751 MGI:MGI:5589910 +102632764 Gm30752 MGI:MGI:5589911 +102632765 Gm30753 MGI:MGI:5589912 +102632766 Gm30754 MGI:MGI:5589913 +102632767 Gm30755 MGI:MGI:5589914 +102632768 Gm30756 MGI:MGI:5589915 +102632769 Gm30757 MGI:MGI:5589916 +102632770 LOC102632770 - +102632771 Gm30758 MGI:MGI:5589917 +102632772 Gm30759 MGI:MGI:5589918 +102632773 Gm30760 MGI:MGI:5589919 +102632774 Gm21847 MGI:MGI:5434011 +102632776 Gm30761 MGI:MGI:5589920 +102632777 Gm30762 MGI:MGI:5589921 +102632778 LOC102632778 - +102632779 Gm30763 MGI:MGI:5589922 +102632780 Gm30764 MGI:MGI:5589923 +102632781 Gm30765 MGI:MGI:5589924 +102632783 Gm30767 MGI:MGI:5589926 +102632785 Gm30769 MGI:MGI:5589928 +102632786 Gm20492 MGI:MGI:5141957|Ensembl:ENSMUSG00000092593 +102632787 Gm30770 MGI:MGI:5589929 +102632788 Gm12040 MGI:MGI:3651597 +102632789 Gm30771 MGI:MGI:5589930 +102632790 Gm30772 MGI:MGI:5589931 +102632793 Gm23011 MGI:MGI:5452788 +102632794 Gm30774 MGI:MGI:5589933 +102632795 Gm30775 MGI:MGI:5589934 +102632797 Gm29249 MGI:MGI:5579955 +102632798 Gm28446 MGI:MGI:5579152 +102632800 Gm30778 MGI:MGI:5589937 +102632801 Gm30779 MGI:MGI:5589938 +102632803 Gm30781 MGI:MGI:5589940 +102632804 Gm30782 MGI:MGI:5589941 +102632805 Gm30783 MGI:MGI:5589942 +102632806 Gm30784 MGI:MGI:5589943 +102632807 Gm30785 MGI:MGI:5589944 +102632808 Gm30786 MGI:MGI:5589945 +102632809 Gm11205 MGI:MGI:3650272 +102632810 Gm30787 MGI:MGI:5589946 +102632811 Gm30788 MGI:MGI:5589947 +102632812 Gm30789 MGI:MGI:5589948 +102632813 Gm15486 MGI:MGI:3705263 +102632814 Gm30790 MGI:MGI:5589949|Ensembl:ENSMUSG00000109333 +102632815 Gm30791 MGI:MGI:5589950 +102632816 Gm30792 MGI:MGI:5589951 +102632818 Gm30794 MGI:MGI:5589953 +102632819 Gm30795 MGI:MGI:5589954 +102632820 Gm13707 MGI:MGI:3651119 +102632821 LOC102632821 Ensembl:ENSMUSG00000086495 +102632822 Gm30796 MGI:MGI:5589955 +102632823 Gm30797 MGI:MGI:5589956 +102632824 Gm26820 MGI:MGI:5477314 +102632825 Gm30798 MGI:MGI:5589957 +102632826 Gm17577 MGI:MGI:4937211 +102632827 Gm30799 MGI:MGI:5589958 +102632829 Gm21256 MGI:MGI:5434611 +102632831 Gm29590 MGI:MGI:5580296 +102632832 Gm28440 MGI:MGI:5579146 +102632833 Gm30802 MGI:MGI:5589961 +102632834 Gm30803 MGI:MGI:5589962 +102632835 Gm30804 MGI:MGI:5589963 +102632836 Gm17147 MGI:MGI:4937974 +102632837 Rnf212b Ensembl:ENSMUSG00000112858 +102632838 Gm30806 MGI:MGI:5589965 +102632839 Gm30807 MGI:MGI:5589966 +102632840 Gm30808 MGI:MGI:5589967|Ensembl:ENSMUSG00000109802 +102632841 Gm30809 MGI:MGI:5589968 +102632842 Gm12322 MGI:MGI:3651558 +102632843 Gm27242 MGI:MGI:5521085 +102632845 Gm30810 MGI:MGI:5589969 +102632847 Gm30812 MGI:MGI:5589971 +102632849 Gm30814 MGI:MGI:5589973 +102632850 Gm30815 MGI:MGI:5589974 +102632851 Gm30816 MGI:MGI:5589975 +102632853 Gm30818 MGI:MGI:5589977 +102632854 Gm17115 MGI:MGI:4937942 +102632856 Gm30820 MGI:MGI:5589979 +102632857 Gm14445 MGI:MGI:3652317 +102632858 Gm30821 MGI:MGI:5589980 +102632859 Gm30822 MGI:MGI:5589981 +102632860 Gm30823 MGI:MGI:5589982 +102632861 Gm30824 MGI:MGI:5589983 +102632863 Gm30826 MGI:MGI:5589985 +102632864 Gm29492 MGI:MGI:5580198 +102632865 Gm30827 MGI:MGI:5589986 +102632866 Gm30828 MGI:MGI:5589987 +102632867 Gm30829 MGI:MGI:5589988 +102632871 Gm30833 MGI:MGI:5589992 +102632873 Gm30835 MGI:MGI:5589994 +102632874 Gm30836 MGI:MGI:5589995 +102632875 Gm30837 MGI:MGI:5589996 +102632876 Gm30838 MGI:MGI:5589997 +102632877 Gm30839 MGI:MGI:5589998 +102632878 Gm30840 MGI:MGI:5589999 +102632880 Gm30842 MGI:MGI:5590001 +102632881 Gm30843 MGI:MGI:5590002 +102632884 Gm30844 MGI:MGI:5590003 +102632886 Gm30845 MGI:MGI:5590004 +102632888 Gm30847 MGI:MGI:5590006 +102632889 Astx4c MGI:MGI:3705270 +102632890 Gm13211 MGI:MGI:3651019 +102632891 Gm30848 MGI:MGI:5590007 +102632892 Gm30849 MGI:MGI:5590008 +102632893 Gm14285 MGI:MGI:3650188 +102632895 Gm30851 MGI:MGI:5590010 +102632896 Gm30852 MGI:MGI:5590011 +102632897 Gm30853 MGI:MGI:5590012|Ensembl:ENSMUSG00000112913 +102632898 Gm16230 MGI:MGI:3802022|Ensembl:ENSMUSG00000087163 +102632900 Gm30855 MGI:MGI:5590014 +102632901 LOC102632901 - +102632904 Gm30858 MGI:MGI:5590017 +102632906 Gm30860 MGI:MGI:5590019 +102632907 LOC102632907 - +102632908 Gm30861 MGI:MGI:5590020 +102632909 Gm28843 MGI:MGI:5579549 +102632911 Gm30863 MGI:MGI:5590022 +102632914 Gm30866 MGI:MGI:5590025 +102632915 Gm30867 MGI:MGI:5590026 +102632916 Gm30868 MGI:MGI:5590027 +102632917 Gm30869 MGI:MGI:5590028 +102632920 Gm30871 MGI:MGI:5590030 +102632921 Gm30872 MGI:MGI:5590031 +102632922 Gm30873 MGI:MGI:5590032 +102632923 Gm30874 MGI:MGI:5590033 +102632924 Gm30875 MGI:MGI:5590034 +102632926 Gm30877 MGI:MGI:5590036 +102632928 Gm17215 MGI:MGI:4938042 +102632930 Gm30880 MGI:MGI:5590039 +102632931 LOC102632931 - +102632932 Gm30881 MGI:MGI:5590040 +102632934 Gm30883 MGI:MGI:5590042 +102632936 Gm30885 MGI:MGI:5590044 +102632938 Gm15939 MGI:MGI:3801831|Ensembl:ENSMUSG00000090087 +102632939 Gm30886 MGI:MGI:5590045 +102632940 Gm11482 MGI:MGI:3652238|Ensembl:ENSMUSG00000086817 +102632942 Gm30888 MGI:MGI:5590047 +102632943 Gm30889 MGI:MGI:5590048 +102632944 Gm30890 MGI:MGI:5590049 +102632945 Gm30891 MGI:MGI:5590050 +102632946 Gm30892 MGI:MGI:5590051 +102632947 Gm15731 MGI:MGI:3783174 +102632948 Gm30893 MGI:MGI:5590052 +102632949 Gm30894 MGI:MGI:5590053 +102632950 Gm30895 MGI:MGI:5590054 +102632951 Gm30896 MGI:MGI:5590055 +102632952 LOC102632952 - +102632954 Gm30898 MGI:MGI:5590057 +102632956 Gm12341 MGI:MGI:3650080 +102632957 LOC102632957 - +102632958 Gm30900 MGI:MGI:5590059 +102632959 Gm30901 MGI:MGI:5590060 +102632960 Gm30902 MGI:MGI:5590061 +102632961 Gm30903 MGI:MGI:5590062 +102632962 Gm30904 MGI:MGI:5590063 +102632963 Gm30905 MGI:MGI:5590064 +102632964 Gm30906 MGI:MGI:5590065 +102632965 Gm30907 MGI:MGI:5590066 +102632966 Gm30908 MGI:MGI:5590067 +102632967 Gm30909 MGI:MGI:5590068 +102632968 Gm30910 MGI:MGI:5590069 +102632969 Gm30911 MGI:MGI:5590070 +102632970 Gm30912 MGI:MGI:5590071 +102632971 Scgb2b8-ps MGI:MGI:5578758 +102632972 Gm30913 MGI:MGI:5590072 +102632973 Gm30914 MGI:MGI:5590073 +102632974 Gm30915 MGI:MGI:5590074 +102632975 Gm30916 MGI:MGI:5590075 +102632977 Gm28850 MGI:MGI:5579556|Ensembl:ENSMUSG00000100900 +102632979 Gm29061 MGI:MGI:5579767 +102632980 Gm30918 MGI:MGI:5590077 +102632985 Gm30922 MGI:MGI:5590081 +102632986 Gm16035 MGI:MGI:3801892 +102632988 Gm30924 MGI:MGI:5590083 +102632989 Gm30925 MGI:MGI:5590084 +102632990 LOC102632990 - +102632991 Gm30926 MGI:MGI:5590085 +102632992 Gm30927 MGI:MGI:5590086 +102632993 Gm30928 MGI:MGI:5590087 +102632994 Gm11592 MGI:MGI:3650504 +102632995 Gm30929 MGI:MGI:5590088 +102632997 Gm29214 MGI:MGI:5579920 +102632998 Gm30931 MGI:MGI:5590090|Ensembl:ENSMUSG00000110035 +102632999 Gm30932 MGI:MGI:5590091 +102633000 LOC102633000 - +102633001 Gm30933 MGI:MGI:5590092 +102633002 Gm30934 MGI:MGI:5590093 +102633003 Gm30935 MGI:MGI:5590094 +102633004 Gm30936 MGI:MGI:5590095 +102633006 Gm30938 MGI:MGI:5590097 +102633007 Gm26564 MGI:MGI:5477058 +102633008 Gm38450 MGI:MGI:5621335 +102633009 Gm30939 MGI:MGI:5590098 +102633010 Gm30940 MGI:MGI:5590099 +102633011 Gm30941 MGI:MGI:5590100 +102633012 Gm30942 MGI:MGI:5590101 +102633013 Gm30943 MGI:MGI:5590102 +102633014 Gm30944 MGI:MGI:5590103 +102633016 Gm30946 MGI:MGI:5590105 +102633017 Gm21744 MGI:MGI:5433908 +102633020 Gm30948 MGI:MGI:5590107|Ensembl:ENSMUSG00000103168 +102633021 Gm30949 MGI:MGI:5590108 +102633022 Gm29320 MGI:MGI:5580026 +102633023 Gm21759 MGI:MGI:5433923 +102633024 Gm29559 MGI:MGI:5580265 +102633025 Gm30950 MGI:MGI:5590109 +102633026 Gm13717 MGI:MGI:3650430 +102633029 Gm30953 MGI:MGI:5590112 +102633030 Gm30954 MGI:MGI:5590113|Ensembl:ENSMUSG00000109260 +102633032 LOC102633032 - +102633033 Gm30956 MGI:MGI:5590115 +102633034 Gm30957 MGI:MGI:5590116 +102633035 Gm28979 MGI:MGI:5579685|Ensembl:ENSMUSG00000101941 +102633037 Gm30958 MGI:MGI:5590117 +102633038 Gm30959 MGI:MGI:5590118 +102633039 Gm30960 MGI:MGI:5590119 +102633040 Gm30961 MGI:MGI:5590120 +102633041 Gm30962 MGI:MGI:5590121 +102633042 Gm30963 MGI:MGI:5590122 +102633043 Gm30964 MGI:MGI:5590123 +102633044 Gm14808 MGI:MGI:3705252 +102633046 Gm30966 MGI:MGI:5590125 +102633048 Gm30967 MGI:MGI:5590126 +102633049 Gm30968 MGI:MGI:5590127 +102633050 LOC102633050 - +102633051 Gm30969 MGI:MGI:5590128 +102633052 Gm30970 MGI:MGI:5590129 +102633053 Gm30971 MGI:MGI:5590130 +102633054 Gm45917 MGI:MGI:5825554 +102633055 Gm30972 MGI:MGI:5590131 +102633056 Gm30973 MGI:MGI:5590132 +102633057 Gm30974 MGI:MGI:5590133 +102633058 Gm30975 MGI:MGI:5590134 +102633059 Gm30976 MGI:MGI:5590135 +102633060 Gm30977 MGI:MGI:5590136 +102633061 Gm30978 MGI:MGI:5590137 +102633065 Gm13470 MGI:MGI:3649387 +102633067 Gm30983 MGI:MGI:5590142 +102633068 Gm30984 MGI:MGI:5590143 +102633069 Gm30985 MGI:MGI:5590144 +102633070 Gm30986 MGI:MGI:5590145 +102633071 Gm14167 MGI:MGI:3651481|Ensembl:ENSMUSG00000087433 +102633074 Gm30989 MGI:MGI:5590148 +102633075 Gm30990 MGI:MGI:5590149 +102633076 LOC102633076 - +102633077 Gm30991 MGI:MGI:5590150 +102633078 Gm30992 MGI:MGI:5590151 +102633079 Gm30993 MGI:MGI:5590152 +102633081 Gm12610 MGI:MGI:3652143 +102633082 Gm30995 MGI:MGI:5590154 +102633083 Gm30996 MGI:MGI:5590155 +102633084 Gm21902 MGI:MGI:5434066 +102633086 LOC102633086 - +102633087 Gm30998 MGI:MGI:5590157 +102633088 Gm30999 MGI:MGI:5590158 +102633089 LOC102633089 - +102633091 Gm31001 MGI:MGI:5590160 +102633093 Gm31003 MGI:MGI:5590162 +102633094 Gm31004 MGI:MGI:5590163 +102633095 Gm31005 MGI:MGI:5590164 +102633096 Gm31006 MGI:MGI:5590165 +102633097 Gm31007 MGI:MGI:5590166 +102633100 Gm31009 MGI:MGI:5590168|Ensembl:ENSMUSG00000074011|Vega:OTTMUSG00000055726 +102633102 Gm31011 MGI:MGI:5590170 +102633103 Gm31012 MGI:MGI:5590171 +102633104 Gm31013 MGI:MGI:5590172|Ensembl:ENSMUSG00000111867 +102633106 Gm31014 MGI:MGI:5590173 +102633107 Gm31015 MGI:MGI:5590174 +102633108 Gm31016 MGI:MGI:5590175 +102633109 Gm11884 MGI:MGI:3651157 +102633110 Gm31017 MGI:MGI:5590176 +102633111 Gm31018 MGI:MGI:5590177 +102633112 Gm31019 MGI:MGI:5590178 +102633113 Gm31020 MGI:MGI:5590179 +102633115 Gm31022 MGI:MGI:5590181 +102633116 Gm31023 MGI:MGI:5590182 +102633117 Gm31024 MGI:MGI:5590183 +102633118 Gm31025 MGI:MGI:5590184 +102633119 Gm31026 MGI:MGI:5590185|Ensembl:ENSMUSG00000106577 +102633121 Gm31028 MGI:MGI:5590187 +102633123 Gm28764 MGI:MGI:5579470|Ensembl:ENSMUSG00000101745 +102633126 Gm31032 MGI:MGI:5590191 +102633127 Gm28692 MGI:MGI:5579398 +102633129 Gm31034 MGI:MGI:5590193 +102633131 Gm31035 MGI:MGI:5590194 +102633132 Gm31036 MGI:MGI:5590195 +102633133 Gm31037 MGI:MGI:5590196 +102633134 Gm31038 MGI:MGI:5590197 +102633135 Gm31039 MGI:MGI:5590198 +102633136 Gm31040 MGI:MGI:5590199 +102633140 Gm31042 MGI:MGI:5590201 +102633142 Gm31044 MGI:MGI:5590203 +102633143 Gm31045 MGI:MGI:5590204 +102633144 Gm31046 MGI:MGI:5590205 +102633145 Gm31047 MGI:MGI:5590206 +102633146 Gm31048 MGI:MGI:5590207 +102633147 Gm31049 MGI:MGI:5590208 +102633148 Gm31050 MGI:MGI:5590209 +102633149 LOC102633149 - +102633151 LOC102633151 - +102633152 Gm28703 MGI:MGI:5579409 +102633153 Gm31052 MGI:MGI:5590211 +102633155 Gm31054 MGI:MGI:5590213 +102633156 LOC102633156 Ensembl:ENSMUSG00000078899|Vega:OTTMUSG00000033975 +102633157 Gm31055 MGI:MGI:5590214 +102633158 Gm31056 MGI:MGI:5590215 +102633159 Gm31057 MGI:MGI:5590216 +102633160 Gm31058 MGI:MGI:5590217 +102633162 Gm31059 MGI:MGI:5590218 +102633163 Gm31060 MGI:MGI:5590219 +102633164 Gm31061 MGI:MGI:5590220 +102633165 Gm38451 MGI:MGI:5621336 +102633167 Gm31063 MGI:MGI:5590222 +102633168 Gm28987 MGI:MGI:5579693|Ensembl:ENSMUSG00000100875 +102633169 Gm31064 MGI:MGI:5590223 +102633170 Gm31065 MGI:MGI:5590224 +102633171 Gm31066 MGI:MGI:5590225 +102633172 Gm31067 MGI:MGI:5590226 +102633174 Gm31068 MGI:MGI:5590227 +102633176 LOC102633176 - +102633177 Gm31069 MGI:MGI:5590228 +102633178 Gm31070 MGI:MGI:5590229 +102633179 Gm15737 MGI:MGI:3783179 +102633181 Gm31072 MGI:MGI:5590231 +102633182 Gm31073 MGI:MGI:5590232 +102633183 Gm12219 MGI:MGI:3649338 +102633184 Gm31074 MGI:MGI:5590233 +102633185 Gm31075 MGI:MGI:5590234 +102633186 Gm31076 MGI:MGI:5590235 +102633187 LOC102633187 - +102633188 Gm31077 MGI:MGI:5590236 +102633189 Gm31078 MGI:MGI:5590237 +102633190 LOC102633190 - +102633192 Gm31080 MGI:MGI:5590239 +102633194 Gm31082 MGI:MGI:5590241 +102633195 Gm31083 MGI:MGI:5590242 +102633196 Gm31084 MGI:MGI:5590243 +102633197 Gm31085 MGI:MGI:5590244 +102633198 Gm31086 MGI:MGI:5590245 +102633199 Gm31087 MGI:MGI:5590246 +102633200 Gm31088 MGI:MGI:5590247 +102633201 LOC102633201 - +102633202 Gm31089 MGI:MGI:5590248 +102633203 Gm31090 MGI:MGI:5590249 +102633204 Gm31091 MGI:MGI:5590250 +102633205 Gm31092 MGI:MGI:5590251 +102633208 Gm31095 MGI:MGI:5590254 +102633209 Gm31096 MGI:MGI:5590255 +102633210 LOC102633210 - +102633211 Gm31097 MGI:MGI:5590256 +102633212 Gm28468 MGI:MGI:5579174 +102633213 Gm20658 MGI:MGI:5313105 +102633214 Gm12925 MGI:MGI:3651536 +102633217 Gm29633 MGI:MGI:5580339 +102633219 Gm31101 MGI:MGI:5590260 +102633220 Gm31102 MGI:MGI:5590261 +102633221 Gm31103 MGI:MGI:5590262 +102633222 Gm31104 MGI:MGI:5590263 +102633223 Gm31105 MGI:MGI:5590264 +102633224 Gm31106 MGI:MGI:5590265 +102633226 Gm31107 MGI:MGI:5590266 +102633227 Gm31108 MGI:MGI:5590267 +102633229 Gm31109 MGI:MGI:5590268 +102633230 LOC102633230 - +102633232 LOC102633232 - +102633233 Gm31111 MGI:MGI:5590270 +102633235 Gm31113 MGI:MGI:5590272 +102633236 Gm13481 MGI:MGI:3651624 +102633237 Gm31114 MGI:MGI:5590273 +102633238 Gm29521 MGI:MGI:5580227 +102633239 LOC102633239 - +102633240 Gm31115 MGI:MGI:5590274 +102633241 Gm31116 MGI:MGI:5590275 +102633242 Gm31117 MGI:MGI:5590276 +102633243 Gm31118 MGI:MGI:5590277 +102633244 Gm26710 MGI:MGI:5477204 +102633245 Gm15723 MGI:MGI:3783167 +102633246 Gm12087 MGI:MGI:3650338 +102633247 Gm31119 MGI:MGI:5590278 +102633248 Gm31120 MGI:MGI:5590279 +102633249 Gm31121 MGI:MGI:5590280|Ensembl:ENSMUSG00000104785 +102633250 Astx2 MGI:MGI:3705176 +102633252 Gm31123 MGI:MGI:5590282 +102633253 Gm21791 MGI:MGI:5433955 +102633254 LOC102633254 - +102633256 Gm21094 MGI:MGI:5434449 +102633257 Gm31125 MGI:MGI:5590284 +102633258 Gm31126 MGI:MGI:5590285 +102633259 Gm16249 MGI:MGI:3826524|Ensembl:ENSMUSG00000084949 +102633260 Gm31127 MGI:MGI:5590286 +102633261 Gm31128 MGI:MGI:5590287 +102633262 Gm31129 MGI:MGI:5590288 +102633263 Gm31130 MGI:MGI:5590289 +102633264 Gm31131 MGI:MGI:5590290 +102633265 Gm31132 MGI:MGI:5590291 +102633266 LOC102633266 - +102633267 Gm31133 MGI:MGI:5590292 +102633269 Gm10087 MGI:MGI:3809877 +102633270 Gm31134 MGI:MGI:5590293 +102633271 Gm31135 MGI:MGI:5590294 +102633272 Gm31136 MGI:MGI:5590295 +102633273 Gm31137 MGI:MGI:5590296 +102633274 LOC102633274 - +102633275 Gm31138 MGI:MGI:5590297 +102633277 Gm38452 MGI:MGI:5621337 +102633278 Gm31140 MGI:MGI:5590299 +102633279 Gm31141 MGI:MGI:5590300 +102633280 Gm31142 MGI:MGI:5590301 +102633281 Gm31143 MGI:MGI:5590302 +102633282 Gm31144 MGI:MGI:5590303 +102633283 Gm31145 MGI:MGI:5590304 +102633284 Gm13787 MGI:MGI:3650035 +102633285 Gm31146 MGI:MGI:5590305 +102633286 Gm31147 MGI:MGI:5590306 +102633287 Gm31148 MGI:MGI:5590307 +102633290 Gm31151 MGI:MGI:5590310 +102633291 Gm31152 MGI:MGI:5590311 +102633293 Gm31154 MGI:MGI:5590313 +102633294 Gm31155 MGI:MGI:5590314 +102633295 Gm15075 MGI:MGI:3705693 +102633296 Gm31156 MGI:MGI:5590315 +102633297 Gm31157 MGI:MGI:5590316 +102633299 Gm28815 MGI:MGI:5579521 +102633300 Gm31159 MGI:MGI:5590318 +102633301 Gm31160 MGI:MGI:5590319 +102633302 Gm31161 MGI:MGI:5590320 +102633303 Gm31162 MGI:MGI:5590321 +102633305 Gm31164 MGI:MGI:5590323 +102633306 Gm31165 MGI:MGI:5590324 +102633307 Gm31166 MGI:MGI:5590325 +102633308 LOC102633308 - +102633311 Gm31169 MGI:MGI:5590328 +102633312 LOC102633312 - +102633313 Gm11533 MGI:MGI:3651874 +102633315 Gm16159 MGI:MGI:3801949|Ensembl:ENSMUSG00000086134 +102633316 Gm31171 MGI:MGI:5590330 +102633317 Gm31172 MGI:MGI:5590331 +102633320 Gm31175 MGI:MGI:5590334 +102633321 LOC102633321 Ensembl:ENSMUSG00000097463 +102633322 LOC102633322 - +102633324 Gm16142 MGI:MGI:3802121|Ensembl:ENSMUSG00000087469 +102633325 Gm31177 MGI:MGI:5590336 +102633326 Gm31178 MGI:MGI:5590337 +102633327 Gm31179 MGI:MGI:5590338 +102633329 Gm31180 MGI:MGI:5590339 +102633330 Gm31181 MGI:MGI:5590340 +102633331 Gm31182 MGI:MGI:5590341 +102633332 LOC102633332 - +102633333 Scgb2b13-ps MGI:MGI:5578749 +102633334 Gm31183 MGI:MGI:5590342 +102633337 Gm31186 MGI:MGI:5590345 +102633338 Gm31187 MGI:MGI:5590346 +102633339 Gm12786 MGI:MGI:3650114 +102633340 Gm31188 MGI:MGI:5590347 +102633341 Gm31189 MGI:MGI:5590348 +102633342 Gm31190 MGI:MGI:5590349 +102633343 Gm31191 MGI:MGI:5590350 +102633344 Gm31192 MGI:MGI:5590351 +102633345 LOC102633345 - +102633346 Gm31193 MGI:MGI:5590352 +102633347 Gm26708 MGI:MGI:5477202 +102633348 Gm31194 MGI:MGI:5590353 +102633349 Gm31195 MGI:MGI:5590354 +102633350 Gm31196 MGI:MGI:5590355 +102633352 Gm31197 MGI:MGI:5590356 +102633353 Gm31198 MGI:MGI:5590357 +102633354 Gm31199 MGI:MGI:5590358 +102633355 Gm31200 MGI:MGI:5590359 +102633356 Gm31201 MGI:MGI:5590360 +102633357 LOC102633357 - +102633358 Gm31202 MGI:MGI:5590361 +102633360 Gm31204 MGI:MGI:5590363 +102633361 Gm31205 MGI:MGI:5590364 +102633362 Gm31206 MGI:MGI:5590365 +102633364 Gm31207 MGI:MGI:5590366 +102633365 Gm31208 MGI:MGI:5590367 +102633366 LOC102633366 - +102633367 Gm31209 MGI:MGI:5590368 +102633368 Gm31210 MGI:MGI:5590369 +102633369 Gm31211 MGI:MGI:5590370 +102633371 Gm14902 MGI:MGI:3705109 +102633372 Gm31213 MGI:MGI:5590372 +102633373 Gm31214 MGI:MGI:5590373 +102633375 Gm28617 MGI:MGI:5579323|Ensembl:ENSMUSG00000100508 +102633376 Gm12924 MGI:MGI:3651538 +102633377 Gm21849 MGI:MGI:5434013 +102633379 Gm29108 MGI:MGI:5579814 +102633380 Gm31216 MGI:MGI:5590375 +102633381 Gm31217 MGI:MGI:5590376 +102633383 Gm31218 MGI:MGI:5590377|Ensembl:ENSMUSG00000113244 +102633384 Gm31219 MGI:MGI:5590378 +102633385 Gm31220 MGI:MGI:5590379 +102633386 Gm31221 MGI:MGI:5590380 +102633387 Gm31222 MGI:MGI:5590381 +102633388 Gm31223 MGI:MGI:5590382 +102633389 Gm31224 MGI:MGI:5590383 +102633390 Gm31225 MGI:MGI:5590384 +102633391 Gm31226 MGI:MGI:5590385 +102633392 Gm31227 MGI:MGI:5590386 +102633393 Gm31228 MGI:MGI:5590387 +102633394 Gm31229 MGI:MGI:5590388 +102633395 Gm31230 MGI:MGI:5590389 +102633396 Gm31231 MGI:MGI:5590390 +102633398 Gm31233 MGI:MGI:5590392 +102633399 Gm31234 MGI:MGI:5590393 +102633400 Gm20506 MGI:MGI:5141971 +102633401 Gm31235 MGI:MGI:5590394 +102633402 Gm31236 MGI:MGI:5590395 +102633403 Gm31237 MGI:MGI:5590396 +102633405 Gm31239 MGI:MGI:5590398 +102633406 Gm31240 MGI:MGI:5590399 +102633407 Gm26847 MGI:MGI:5477341 +102633409 Gm31242 MGI:MGI:5590401 +102633410 Gm31243 MGI:MGI:5590402 +102633411 Gm31244 MGI:MGI:5590403 +102633413 Gm29530 MGI:MGI:5580236 +102633416 Gm31248 MGI:MGI:5590407 +102633417 Gm31249 MGI:MGI:5590408 +102633418 Gm31250 MGI:MGI:5590409 +102633419 Gm31251 MGI:MGI:5590410 +102633420 Gm12223 MGI:MGI:3649594 +102633421 Gm31252 MGI:MGI:5590411 +102633422 Gm31253 MGI:MGI:5590412 +102633423 Gm31254 MGI:MGI:5590413 +102633424 Gm31255 MGI:MGI:5590414 +102633425 LOC102633425 - +102633426 Gm31256 MGI:MGI:5590415 +102633428 Gm31258 MGI:MGI:5590417 +102633429 Gm31259 MGI:MGI:5590418 +102633430 Gm31260 MGI:MGI:5590419 +102633431 Gm31261 MGI:MGI:5590420 +102633432 Gm31262 MGI:MGI:5590421 +102633433 Gm29478 MGI:MGI:5580184 +102633434 Gm31263 MGI:MGI:5590422 +102633435 Gm26535 MGI:MGI:5477029 +102633436 Gm11217 MGI:MGI:3651042 +102633437 Gm31264 MGI:MGI:5590423 +102633438 Gm13974 MGI:MGI:3649228 +102633439 Gm14154 MGI:MGI:3649354 +102633440 Gm26763 MGI:MGI:5477257 +102633441 Gm31265 MGI:MGI:5590424 +102633442 Gm31266 MGI:MGI:5590425 +102633443 Gm31267 MGI:MGI:5590426 +102633444 Gm31268 MGI:MGI:5590427 +102633445 Gm31269 MGI:MGI:5590428 +102633448 Gm28127 MGI:MGI:5578833|Ensembl:ENSMUSG00000101560 +102633449 Gm31271 MGI:MGI:5590430 +102633451 Gm29110 MGI:MGI:5579816 +102633452 Gm38453 MGI:MGI:5621338 +102633453 Gm31273 MGI:MGI:5590432 +102633454 Gm31274 MGI:MGI:5590433 +102633455 Gm31275 MGI:MGI:5590434 +102633457 Gm31276 MGI:MGI:5590435 +102633458 Gm11100 MGI:MGI:3779338 +102633459 Gm31277 MGI:MGI:5590436 +102633460 Gm31278 MGI:MGI:5590437 +102633461 Gm31279 MGI:MGI:5590438 +102633463 Gm31281 MGI:MGI:5590440 +102633464 Gm31282 MGI:MGI:5590441 +102633465 Gm31283 MGI:MGI:5590442 +102633466 Gm31284 MGI:MGI:5590443 +102633467 Gm31285 MGI:MGI:5590444 +102633468 Gm31286 MGI:MGI:5590445 +102633469 LOC102633469 - +102633470 Gm31287 MGI:MGI:5590446 +102633471 Gm31288 MGI:MGI:5590447 +102633472 LOC102633472 - +102633473 Gm31289 MGI:MGI:5590448 +102633474 Gm31290 MGI:MGI:5590449 +102633475 Gm31291 MGI:MGI:5590450 +102633476 Gm31292 MGI:MGI:5590451 +102633477 Gm27243 MGI:MGI:5521086 +102633478 Gm16090 MGI:MGI:3801885|Ensembl:ENSMUSG00000085595 +102633479 Gm31293 MGI:MGI:5590452 +102633480 Gm31294 MGI:MGI:5590453 +102633481 Gm31295 MGI:MGI:5590454 +102633482 Gm31296 MGI:MGI:5590455 +102633484 Gm31298 MGI:MGI:5590457 +102633486 Gm31300 MGI:MGI:5590459 +102633487 Gm31301 MGI:MGI:5590460 +102633488 Gm31302 MGI:MGI:5590461 +102633491 Gm31304 MGI:MGI:5590463 +102633492 Gm31305 MGI:MGI:5590464 +102633493 LOC102633493 - +102633494 Gm31306 MGI:MGI:5590465 +102633495 Gm31307 MGI:MGI:5590466 +102633496 Gm31308 MGI:MGI:5590467 +102633497 LOC102633497 - +102633498 Gm31309 MGI:MGI:5590468 +102633500 Gm31311 MGI:MGI:5590470 +102633501 Gm29382 MGI:MGI:5580088 +102633503 Gm31313 MGI:MGI:5590472 +102633504 Gm31314 MGI:MGI:5590473|Ensembl:ENSMUSG00000106938 +102633505 Gm31315 MGI:MGI:5590474 +102633507 Gm31317 MGI:MGI:5590476 +102633508 Gm31318 MGI:MGI:5590477 +102633509 Gm31319 MGI:MGI:5590478 +102633510 Gm31320 MGI:MGI:5590479 +102633511 Gm31321 MGI:MGI:5590480 +102633512 Gm31322 MGI:MGI:5590481 +102633513 Gm31323 MGI:MGI:5590482 +102633515 Gm31324 MGI:MGI:5590483 +102633516 Peak1os MGI:MGI:5477083 +102633517 Gm31325 MGI:MGI:5590484 +102633518 Gm31326 MGI:MGI:5590485 +102633520 Gm31328 MGI:MGI:5590487 +102633521 Gm31329 MGI:MGI:5590488 +102633522 Gm31330 MGI:MGI:5590489 +102633523 LOC102633523 - +102633524 Gm31331 MGI:MGI:5590490 +102633525 Gm31332 MGI:MGI:5590491 +102633526 Gm31333 MGI:MGI:5590492 +102633528 Gm31335 MGI:MGI:5590494 +102633529 Gm29333 MGI:MGI:5580039 +102633530 Gm31336 MGI:MGI:5590495 +102633531 Gm28814 MGI:MGI:5579520 +102633532 Gm28609 MGI:MGI:5579315 +102633533 Gm31337 MGI:MGI:5590496 +102633537 Gm31340 MGI:MGI:5590499 +102633538 Gm31341 MGI:MGI:5590500 +102633539 Gm15661 MGI:MGI:3783103 +102633540 Myhas MGI:MGI:3650429 +102633541 LOC102633541 - +102633542 Gm11699 MGI:MGI:3650316 +102633543 Gm31342 MGI:MGI:5590501 +102633544 Gm31343 MGI:MGI:5590502 +102633545 Gm31344 MGI:MGI:5590503 +102633546 Gm31345 MGI:MGI:5590504 +102633548 LOC102633548 - +102633549 Gm31347 MGI:MGI:5590506 +102633550 Gm31348 MGI:MGI:5590507 +102633551 Gm31349 MGI:MGI:5590508 +102633553 LOC102633553 - +102633554 Gm31351 MGI:MGI:5590510 +102633555 Gm14051 MGI:MGI:3650008|Ensembl:ENSMUSG00000086756 +102633556 Gm31352 MGI:MGI:5590511 +102633557 Gm31353 MGI:MGI:5590512 +102633559 Gm31355 MGI:MGI:5590514 +102633560 Gm31356 MGI:MGI:5590515 +102633562 Gm31358 MGI:MGI:5590517 +102633563 Gm31359 MGI:MGI:5590518 +102633564 Gm28919 MGI:MGI:5579625 +102633566 Gm29321 MGI:MGI:5580027 +102633570 Gm21752 MGI:MGI:5433916 +102633571 Gm31363 MGI:MGI:5590522 +102633572 Gm31364 MGI:MGI:5590523 +102633573 Gm31365 MGI:MGI:5590524 +102633575 Gm31367 MGI:MGI:5590526 +102633576 LOC102633576 - +102633578 Gm31369 MGI:MGI:5590528 +102633579 Gm31370 MGI:MGI:5590529 +102633580 Gm31371 MGI:MGI:5590530 +102633582 Gm31373 MGI:MGI:5590532 +102633583 Gm31374 MGI:MGI:5590533 +102633584 LOC102633584 - +102633585 Gm31375 MGI:MGI:5590534 +102633588 LOC102633588 - +102633590 Gm31378 MGI:MGI:5590537 +102633591 Gm31379 MGI:MGI:5590538 +102633593 AA387200 MGI:MGI:3034170 +102633596 LOC102633596 - +102633597 Gm31383 MGI:MGI:5590542 +102633598 Gm31384 MGI:MGI:5590543 +102633599 Gm31385 MGI:MGI:5590544 +102633600 Gm26633 MGI:MGI:5477127|Ensembl:ENSMUSG00000097441 +102633601 Gm31386 MGI:MGI:5590545 +102633603 Gm31388 MGI:MGI:5590547 +102633605 LOC102633605 - +102633606 Gm31390 MGI:MGI:5590549 +102633607 Gm31391 MGI:MGI:5590550 +102633608 Gm31392 MGI:MGI:5590551 +102633609 Gm31393 MGI:MGI:5590552 +102633610 Gm31394 MGI:MGI:5590553 +102633611 Gm31395 MGI:MGI:5590554 +102633615 Gm31399 MGI:MGI:5590558 +102633616 Gm31400 MGI:MGI:5590559 +102633617 Gm31401 MGI:MGI:5590560 +102633618 Gm31402 MGI:MGI:5590561 +102633620 Gm31404 MGI:MGI:5590563 +102633621 Gm31405 MGI:MGI:5590564 +102633622 Gm31406 MGI:MGI:5590565 +102633623 Gm31407 MGI:MGI:5590566 +102633624 Gm31408 MGI:MGI:5590567|Ensembl:ENSMUSG00000111853 +102633625 Gm31409 MGI:MGI:5590568 +102633626 Gm31410 MGI:MGI:5590569 +102633627 LOC102633627 - +102633630 Gm31413 MGI:MGI:5590572 +102633631 Gm31414 MGI:MGI:5590573 +102633632 Gm31415 MGI:MGI:5590574 +102633633 Gm31416 MGI:MGI:5590575 +102633634 Gm26876 MGI:MGI:5477370 +102633635 Gm31417 MGI:MGI:5590576 +102633636 Gm31418 MGI:MGI:5590577 +102633638 Gm31419 MGI:MGI:5590578 +102633639 Gm31420 MGI:MGI:5590579 +102633640 Gm31421 MGI:MGI:5590580 +102633641 Gm31422 MGI:MGI:5590581 +102633642 Gm28337 MGI:MGI:5579043 +102633643 LOC102633643 - +102633644 Gm28687 MGI:MGI:5579393 +102633645 Gm28844 MGI:MGI:5579550 +102633646 Gm31423 MGI:MGI:5590582 +102633651 Gm14532 MGI:MGI:3705266 +102633653 Gm31427 MGI:MGI:5590586 +102633654 Gm31428 MGI:MGI:5590587 +102633655 LOC102633655 - +102633657 Gm31429 MGI:MGI:5590588 +102633659 Gm31430 MGI:MGI:5590589 +102633660 Gm31431 MGI:MGI:5590590 +102633661 Gm31432 MGI:MGI:5590591 +102633662 Gm31433 MGI:MGI:5590592 +102633663 Gm31434 MGI:MGI:5590593 +102633664 Gm31435 MGI:MGI:5590594 +102633665 Gm31436 MGI:MGI:5590595 +102633666 LOC102633666 - +102633667 Gm31437 MGI:MGI:5590596 +102633668 Gm31438 MGI:MGI:5590597 +102633669 Gm31439 MGI:MGI:5590598 +102633671 LOC102633671 - +102633673 Etaa1os MGI:MGI:1920221|Ensembl:ENSMUSG00000086468 +102633674 Gm31441 MGI:MGI:5590600 +102633675 Gm31442 MGI:MGI:5590601 +102633676 Gm31443 MGI:MGI:5590602 +102633677 LOC102633677 - +102633678 Gm31444 MGI:MGI:5590603 +102633679 Gm31445 MGI:MGI:5590604 +102633680 Gm31446 MGI:MGI:5590605 +102633681 Gm14991 MGI:MGI:3705875 +102633682 Gm31447 MGI:MGI:5590606 +102633683 Gm21853 MGI:MGI:5434017 +102633684 Gm31448 MGI:MGI:5590607 +102633685 Gm31449 MGI:MGI:5590608 +102633686 Gm31450 MGI:MGI:5590609 +102633687 Gm31451 MGI:MGI:5590610 +102633688 Gm28441 MGI:MGI:5579147|Ensembl:ENSMUSG00000100830 +102633689 Gm31452 MGI:MGI:5590611 +102633690 Gm31453 MGI:MGI:5590612 +102633692 Gm15395 MGI:MGI:3705091 +102633693 Gm31455 MGI:MGI:5590614 +102633694 Gm31456 MGI:MGI:5590615 +102633695 Gm31457 MGI:MGI:5590616 +102633696 Gm17654 MGI:MGI:4937288 +102633697 Gm31458 MGI:MGI:5590617 +102633698 Gm31459 MGI:MGI:5590618 +102633699 Gm31460 MGI:MGI:5590619 +102633700 Gm31461 MGI:MGI:5590620 +102633701 Gm31462 MGI:MGI:5590621 +102633702 Gm31463 MGI:MGI:5590622|Ensembl:ENSMUSG00000108932 +102633703 Gm31464 MGI:MGI:5590623 +102633704 Gm31465 MGI:MGI:5590624 +102633705 LOC102633705 - +102633706 Gm31466 MGI:MGI:5590625 +102633707 Gm31467 MGI:MGI:5590626 +102633708 Gm31468 MGI:MGI:5590627 +102633709 Gm31469 MGI:MGI:5590628 +102633711 Gm15320 MGI:MGI:3782934 +102633712 Gm31471 MGI:MGI:5590630 +102633713 Gm31472 MGI:MGI:5590631 +102633714 Gm31473 MGI:MGI:5590632 +102633715 Gm31474 MGI:MGI:5590633 +102633716 Gm31475 MGI:MGI:5590634 +102633717 Gm31476 MGI:MGI:5590635 +102633718 Gm31477 MGI:MGI:5590636 +102633720 Gm29638 MGI:MGI:5580344 +102633721 Gm31479 MGI:MGI:5590638 +102633724 LOC102633724 - +102633725 Gm31482 MGI:MGI:5590641 +102633726 Gm21906 MGI:MGI:5434070 +102633727 Gm28225 MGI:MGI:5578931|Ensembl:ENSMUSG00000100532 +102633728 Gm31483 MGI:MGI:5590642 +102633729 Gm31484 MGI:MGI:5590643 +102633730 Gm31485 MGI:MGI:5590644 +102633732 Gm31486 MGI:MGI:5590645 +102633733 Gm31487 MGI:MGI:5590646 +102633735 Gm31489 MGI:MGI:5590648 +102633737 Gm31490 MGI:MGI:5590649 +102633738 Gm31491 MGI:MGI:5590650 +102633739 Gm31492 MGI:MGI:5590651 +102633740 Gm31493 MGI:MGI:5590652 +102633741 Gm31494 MGI:MGI:5590653 +102633742 Gm31495 MGI:MGI:5590654 +102633743 Gm31496 MGI:MGI:5590655 +102633744 Gm31497 MGI:MGI:5590656 +102633747 Gm31499 MGI:MGI:5590658 +102633748 Gm31500 MGI:MGI:5590659 +102633749 Gm31501 MGI:MGI:5590660 +102633750 Gm10130 MGI:MGI:3642547 +102633751 Gm31502 MGI:MGI:5590661 +102633752 Gm31503 MGI:MGI:5590662 +102633753 LOC102633753 - +102633754 Gm31504 MGI:MGI:5590663 +102633755 Gm31505 MGI:MGI:5590664 +102633758 Gm31508 MGI:MGI:5590667 +102633760 Gm31510 MGI:MGI:5590669 +102633761 Gm31511 MGI:MGI:5590670 +102633762 Gm31512 MGI:MGI:5590671 +102633763 Gm31513 MGI:MGI:5590672 +102633764 Gm31514 MGI:MGI:5590673 +102633765 Gm26606 MGI:MGI:5477100 +102633766 Gm28365 MGI:MGI:5579071|Ensembl:ENSMUSG00000099496 +102633768 Gm31515 MGI:MGI:5590674 +102633769 Gm31516 MGI:MGI:5590675 +102633770 Gm31517 MGI:MGI:5590676 +102633771 Gm31518 MGI:MGI:5590677|Ensembl:ENSMUSG00000110447 +102633772 Gm31519 MGI:MGI:5590678 +102633773 Gm31520 MGI:MGI:5590679|Ensembl:ENSMUSG00000107653 +102633774 Gm31521 MGI:MGI:5590680 +102633775 Gm31522 MGI:MGI:5590681 +102633776 Gm31523 MGI:MGI:5590682 +102633779 Gm31525 MGI:MGI:5590684 +102633780 Gm28321 MGI:MGI:5579027 +102633781 Gm29183 MGI:MGI:5579889 +102633782 Gm31526 MGI:MGI:5590685 +102633783 LOC102633783 Ensembl:ENSMUSG00000094874 +102633784 LOC102633784 - +102633785 Gm31527 MGI:MGI:5590686 +102633788 Gm31529 MGI:MGI:5590688 +102633789 Gm31530 MGI:MGI:5590689 +102633790 Gm31531 MGI:MGI:5590690 +102633791 Gm31532 MGI:MGI:5590691 +102633792 Gm31533 MGI:MGI:5590692 +102633793 Gm31534 MGI:MGI:5590693 +102633794 LOC102633794 - +102633795 Gm31535 MGI:MGI:5590694 +102633796 Gm31536 MGI:MGI:5590695 +102633797 Gm31537 MGI:MGI:5590696 +102633798 Gm31538 MGI:MGI:5590697 +102633799 Gm29087 MGI:MGI:5579793 +102633800 LOC102633800 - +102633801 Gm28130 MGI:MGI:5578836 +102633802 Gm31539 MGI:MGI:5590698 +102633804 Gm15522 MGI:MGI:3782969 +102633805 Gm26688 MGI:MGI:5477182|Ensembl:ENSMUSG00000097752 +102633807 Gm31542 MGI:MGI:5590701 +102633808 Gm31543 MGI:MGI:5590702 +102633809 LOC102633809 - +102633810 Gm31544 MGI:MGI:5590703 +102633811 Gm31545 MGI:MGI:5590704 +102633812 Gm31546 MGI:MGI:5590705 +102633813 Gm38454 MGI:MGI:5621339 +102633814 Gm31547 MGI:MGI:5590706 +102633815 Gm31548 MGI:MGI:5590707 +102633817 LOC102633817 - +102633818 Gm31550 MGI:MGI:5590709 +102633819 Gm31551 MGI:MGI:5590710 +102633820 Gm31552 MGI:MGI:5590711 +102633821 Gm31553 MGI:MGI:5590712 +102633822 Gm31554 MGI:MGI:5590713 +102633823 Gm31555 MGI:MGI:5590714 +102633824 Gm13261 MGI:MGI:3650831 +102633825 Gm31556 MGI:MGI:5590715 +102633826 Gm31557 MGI:MGI:5590716 +102633827 Gm31558 MGI:MGI:5590717 +102633828 Gm31559 MGI:MGI:5590718 +102633829 Gm31560 MGI:MGI:5590719 +102633831 Gm31562 MGI:MGI:5590721|Ensembl:ENSMUSG00000111008 +102633832 Gm31563 MGI:MGI:5590722 +102633833 Gm38455 MGI:MGI:5621340 +102633834 Gm31564 MGI:MGI:5590723 +102633835 Gm31565 MGI:MGI:5590724 +102633836 Gm31566 MGI:MGI:5590725 +102633837 Gm31567 MGI:MGI:5590726 +102633838 Gm31568 MGI:MGI:5590727 +102633839 Gm31569 MGI:MGI:5590728 +102633841 Gm16017 MGI:MGI:3802069 +102633842 Gm31571 MGI:MGI:5590730 +102633843 Gm31572 MGI:MGI:5590731 +102633844 Gm12637 MGI:MGI:3650764 +102633845 Gm31573 MGI:MGI:5590732 +102633849 Gm31577 MGI:MGI:5590736 +102633851 Gm31579 MGI:MGI:5590738 +102633854 Gm31581 MGI:MGI:5590740 +102633855 Gm31582 MGI:MGI:5590741 +102633856 Gm31583 MGI:MGI:5590742 +102633859 Gm31584 MGI:MGI:5590743 +102633860 Gm31585 MGI:MGI:5590744 +102633861 Gm31586 MGI:MGI:5590745 +102633862 Gm31587 MGI:MGI:5590746 +102633863 Gm31588 MGI:MGI:5590747 +102633865 Gm31590 MGI:MGI:5590749 +102633867 Gm31592 MGI:MGI:5590751|Ensembl:ENSMUSG00000111657 +102633868 Gm31593 MGI:MGI:5590752 +102633869 LOC102633869 - +102633870 Gm31594 MGI:MGI:5590753 +102633871 Gm31595 MGI:MGI:5590754 +102633872 Gm26544 MGI:MGI:5477038|Ensembl:ENSMUSG00000097362 +102633873 Gm31596 MGI:MGI:5590755 +102633874 Gm31597 MGI:MGI:5590756 +102633875 Gm31598 MGI:MGI:5590757 +102633876 Gm29098 MGI:MGI:5579804 +102633878 Gm31600 MGI:MGI:5590759 +102633879 Gm31601 MGI:MGI:5590760 +102633880 LOC102633880 - +102633882 Gm26761 MGI:MGI:5477255 +102633885 Gm31603 MGI:MGI:5590762 +102633888 Gm31606 MGI:MGI:5590765 +102633889 Gm31607 MGI:MGI:5590766 +102633890 LOC102633890 - +102633891 Gm31608 MGI:MGI:5590767 +102633892 Gm31609 MGI:MGI:5590768 +102633893 LOC102633893 - +102633894 Gm31610 MGI:MGI:5590769 +102633895 Gm31611 MGI:MGI:5590770 +102633896 Gm31612 MGI:MGI:5590771 +102633898 Gm31613 MGI:MGI:5590772 +102633899 Gm31614 MGI:MGI:5590773 +102633900 Gm31615 MGI:MGI:5590774 +102633901 Gm31616 MGI:MGI:5590775 +102633902 Gm31617 MGI:MGI:5590776 +102633903 Gm13785 MGI:MGI:3649781 +102633904 Gm31618 MGI:MGI:5590777 +102633905 Gm31619 MGI:MGI:5590778 +102633906 Gm31620 MGI:MGI:5590779 +102633908 Gm31621 MGI:MGI:5590780 +102633910 Gm16315 MGI:MGI:3826564 +102633911 Gm12022 MGI:MGI:3650976 +102633913 Gm31623 MGI:MGI:5590782 +102633914 Gm31624 MGI:MGI:5590783 +102633917 Gm31626 MGI:MGI:5590785 +102633918 Gm12916 MGI:MGI:3649992 +102633919 Gm29248 MGI:MGI:5579954 +102633922 Gm28420 MGI:MGI:5579126 +102633923 Gm31629 MGI:MGI:5590788 +102633924 Gm31630 MGI:MGI:5590789 +102633925 Gm13782 MGI:MGI:3649363 +102633926 Gm31631 MGI:MGI:5590790 +102633927 Gm31632 MGI:MGI:5590791 +102633928 Sox5os4 MGI:MGI:3783128 +102633929 Gm31633 MGI:MGI:5590792 +102633930 LOC102633930 - +102633933 Gm31635 MGI:MGI:5590794 +102633934 Gm31636 MGI:MGI:5590795 +102633935 Gm31637 MGI:MGI:5590796 +102633936 Gm31638 MGI:MGI:5590797 +102633937 Gm31639 MGI:MGI:5590798 +102633938 Gm38456 MGI:MGI:5621341 +102633939 Gm15518 MGI:MGI:3801752 +102633940 Gm31640 MGI:MGI:5590799 +102633941 Gm31641 MGI:MGI:5590800 +102633942 Gm14487 MGI:MGI:3649724|Ensembl:ENSMUSG00000085275 +102633943 Gm31642 MGI:MGI:5590801 +102633944 Gm31643 MGI:MGI:5590802 +102633946 Gm31645 MGI:MGI:5590804 +102633947 Gm31646 MGI:MGI:5590805 +102633948 Gm31647 MGI:MGI:5590806 +102633949 Gm31648 MGI:MGI:5590807 +102633950 Gm26579 MGI:MGI:5477073|Ensembl:ENSMUSG00000097104 +102633951 Gm31649 MGI:MGI:5590808 +102633952 Gm31650 MGI:MGI:5590809 +102633953 Gm31651 MGI:MGI:5590810 +102633955 Gm31652 MGI:MGI:5590811 +102633956 Gm31653 MGI:MGI:5590812 +102633958 Gm31655 MGI:MGI:5590814 +102633959 Gm31656 MGI:MGI:5590815 +102633960 Gm31657 MGI:MGI:5590816 +102633961 Gm31658 MGI:MGI:5590817 +102633962 Gm31659 MGI:MGI:5590818 +102633963 Gm31660 MGI:MGI:5590819 +102633964 Gm31661 MGI:MGI:5590820 +102633965 Gm31662 MGI:MGI:5590821 +102633966 Gm31663 MGI:MGI:5590822 +102633967 Gm31664 MGI:MGI:5590823 +102633968 Gm31665 MGI:MGI:5590824 +102633970 Gm31667 MGI:MGI:5590826 +102633971 Gm31668 MGI:MGI:5590827 +102633972 Gm31669 MGI:MGI:5590828 +102633973 LOC102633973 - +102633974 Gm28905 MGI:MGI:5579611 +102633975 Gm12911 MGI:MGI:3652009 +102633977 Gm31671 MGI:MGI:5590830 +102633978 Gm31672 MGI:MGI:5590831 +102633980 Gm31673 MGI:MGI:5590832 +102633981 Gm31674 MGI:MGI:5590833 +102633983 Gm31676 MGI:MGI:5590835 +102633984 Gm31677 MGI:MGI:5590836 +102633985 Gm31678 MGI:MGI:5590837 +102633986 Gm31679 MGI:MGI:5590838 +102633987 Gm31680 MGI:MGI:5590839 +102633989 Gm31682 MGI:MGI:5590841 +102633990 Gm28907 MGI:MGI:5579613 +102633991 Gm21918 MGI:MGI:5434082 +102633992 Gm29058 MGI:MGI:5579764 +102633993 Gm31683 MGI:MGI:5590842 +102633994 Gm31684 MGI:MGI:5590843 +102633996 Gm31686 MGI:MGI:5590845 +102633997 Gm31687 MGI:MGI:5590846 +102633998 Gm31688 MGI:MGI:5590847 +102634000 Gm31690 MGI:MGI:5590849 +102634001 Gm31691 MGI:MGI:5590850 +102634002 Gm31692 MGI:MGI:5590851 +102634003 Gm31693 MGI:MGI:5590852|Ensembl:ENSMUSG00000105440 +102634004 Gm31694 MGI:MGI:5590853 +102634006 Gm31696 MGI:MGI:5590855 +102634008 Gm31698 MGI:MGI:5590857 +102634009 Gm31699 MGI:MGI:5590858 +102634010 LOC102634010 - +102634011 Gm26868 MGI:MGI:5477362 +102634012 Gm31700 MGI:MGI:5590859 +102634013 Gm31701 MGI:MGI:5590860 +102634015 Gm31703 MGI:MGI:5590862 +102634016 Gm31704 MGI:MGI:5590863 +102634017 Gm13817 MGI:MGI:3649315 +102634018 LOC102634018 - +102634020 Gm31706 MGI:MGI:5590865 +102634021 Gm13001 MGI:MGI:3702655 +102634022 Gm31707 MGI:MGI:5590866 +102634024 Gm31709 MGI:MGI:5590868 +102634027 Gm31711 MGI:MGI:5590870 +102634028 Gm31712 MGI:MGI:5590871 +102634029 Gm31713 MGI:MGI:5590872 +102634030 Gm31714 MGI:MGI:5590873 +102634031 Gm31715 MGI:MGI:5590874 +102634033 Gm31717 MGI:MGI:5590876 +102634034 Gm31718 MGI:MGI:5590877 +102634035 Gm31719 MGI:MGI:5590878 +102634036 Gm13847 MGI:MGI:3651994 +102634037 Gm31720 MGI:MGI:5590879 +102634038 Gm31721 MGI:MGI:5590880 +102634039 Gm20687 MGI:MGI:5313134 +102634040 Gm31722 MGI:MGI:5590881 +102634041 Gm31723 MGI:MGI:5590882 +102634042 LOC102634042 - +102634043 Gm31724 MGI:MGI:5590883 +102634044 Gm31725 MGI:MGI:5590884 +102634045 Gm31726 MGI:MGI:5590885 +102634046 Gm21182 MGI:MGI:5434537 +102634047 Gm31727 MGI:MGI:5590886 +102634049 Gm31728 MGI:MGI:5590887 +102634050 Gm31729 MGI:MGI:5590888 +102634052 Gm31731 MGI:MGI:5590890 +102634054 Gm31733 MGI:MGI:5590892 +102634055 Gm31734 MGI:MGI:5590893 +102634056 Gm31735 MGI:MGI:5590894 +102634058 LOC102634058 - +102634060 Gm19708 MGI:MGI:5011893 +102634061 Gm31739 MGI:MGI:5590898 +102634063 Gm14950 MGI:MGI:3705168|Ensembl:ENSMUSG00000085536 +102634064 Gm31740 MGI:MGI:5590899 +102634065 LOC102634065 - +102634067 Gm31742 MGI:MGI:5590901 +102634068 Gm12907 MGI:MGI:3650882 +102634070 Gm28421 MGI:MGI:5579127 +102634071 Gm31744 MGI:MGI:5590903 +102634072 Gm38457 MGI:MGI:5621342 +102634073 Gm31745 MGI:MGI:5590904 +102634074 Gm31746 MGI:MGI:5590905 +102634075 Gm31747 MGI:MGI:5590906|Ensembl:ENSMUSG00000107441 +102634076 Gm20642 MGI:MGI:5313089 +102634077 Gm31748 MGI:MGI:5590907 +102634078 LOC102634078 - +102634079 Slc36a3os MGI:MGI:3651340|Ensembl:ENSMUSG00000085531 +102634080 Gm31749 MGI:MGI:5590908 +102634081 Gm31750 MGI:MGI:5590909 +102634082 LOC102634082 - +102634083 Gm31751 MGI:MGI:5590910 +102634084 Gm31752 MGI:MGI:5590911|Ensembl:ENSMUSG00000104718 +102634085 Gm37168 MGI:MGI:5610396 +102634086 Gm31753 MGI:MGI:5590912 +102634087 Gm31754 MGI:MGI:5590913 +102634088 Gm31755 MGI:MGI:5590914 +102634089 Gm31756 MGI:MGI:5590915 +102634090 Gm38458 MGI:MGI:5621343 +102634092 Gm31758 MGI:MGI:5590917 +102634093 Gm31759 MGI:MGI:5590918 +102634095 Gm31761 MGI:MGI:5590920 +102634096 Gm11476 MGI:MGI:3705135|Ensembl:ENSMUSG00000085596 +102634097 LOC102634097 - +102634098 LOC102634098 - +102634099 Gm31762 MGI:MGI:5590921 +102634100 Gm38459 MGI:MGI:5621344 +102634101 Gm31763 MGI:MGI:5590922|Ensembl:ENSMUSG00000112925 +102634102 Gm31764 MGI:MGI:5590923 +102634103 Gm31765 MGI:MGI:5590924 +102634107 Gm31769 MGI:MGI:5590928 +102634109 Gm31771 MGI:MGI:5590930 +102634110 Gm31772 MGI:MGI:5590931 +102634111 Gm31773 MGI:MGI:5590932 +102634112 Gm20706 MGI:MGI:5313153 +102634113 Gm31774 MGI:MGI:5590933 +102634114 Gm31775 MGI:MGI:5590934 +102634115 Gm31776 MGI:MGI:5590935 +102634116 Gm31777 MGI:MGI:5590936 +102634119 Gm31780 MGI:MGI:5590939 +102634120 Gm31781 MGI:MGI:5590940 +102634123 Gm31784 MGI:MGI:5590943 +102634124 Gm31785 MGI:MGI:5590944 +102634125 Gm31786 MGI:MGI:5590945 +102634128 LOC102634128 Ensembl:ENSMUSG00000109160 +102634129 Gm16365 MGI:MGI:3840143 +102634130 Gm12446 MGI:MGI:3651433 +102634132 LOC102634132 - +102634133 Gm31790 MGI:MGI:5590949 +102634134 Gm31791 MGI:MGI:5590950 +102634135 LOC102634135 - +102634136 Gm31792 MGI:MGI:5590951 +102634137 Gm31793 MGI:MGI:5590952 +102634138 Gm31794 MGI:MGI:5590953 +102634140 Gm31796 MGI:MGI:5590955 +102634141 Gm31797 MGI:MGI:5590956 +102634142 Gm16198 MGI:MGI:3802052 +102634148 Gm31803 MGI:MGI:5590962 +102634149 Gm31804 MGI:MGI:5590963 +102634150 Gm31805 MGI:MGI:5590964 +102634151 Gm31806 MGI:MGI:5590965 +102634153 Gm31808 MGI:MGI:5590967 +102634154 LOC102634154 - +102634155 Gm17025 MGI:MGI:4937852 +102634157 Gm31810 MGI:MGI:5590969 +102634159 Gm28644 MGI:MGI:5579350 +102634160 Gm31812 MGI:MGI:5590971 +102634161 Gm31813 MGI:MGI:5590972 +102634162 Gm31814 MGI:MGI:5590973 +102634163 Gm31815 MGI:MGI:5590974 +102634165 Gm31816 MGI:MGI:5590975 +102634166 Gm31817 MGI:MGI:5590976 +102634167 Gm31818 MGI:MGI:5590977 +102634168 Gm38460 MGI:MGI:5621345 +102634169 Gm11917 MGI:MGI:3651770 +102634170 Gm31819 MGI:MGI:5590978 +102634171 Gm31820 MGI:MGI:5590979 +102634172 Gm31821 MGI:MGI:5590980 +102634174 Gm16104 MGI:MGI:3801749|Ensembl:ENSMUSG00000085327 +102634175 Gm31822 MGI:MGI:5590981 +102634178 Gm31825 MGI:MGI:5590984 +102634181 Gm21890 MGI:MGI:5434054 +102634182 Gm31827 MGI:MGI:5590986 +102634183 Gm31828 MGI:MGI:5590987 +102634184 Gm31829 MGI:MGI:5590988 +102634185 Gm31830 MGI:MGI:5590989 +102634186 Gm28908 MGI:MGI:5579614 +102634187 Gm31831 MGI:MGI:5590990 +102634188 Gm29639 MGI:MGI:5580345 +102634189 Gm31832 MGI:MGI:5590991 +102634191 Gm31834 MGI:MGI:5590993 +102634193 Gm31835 MGI:MGI:5590994 +102634194 Gm29461 MGI:MGI:5580167|Ensembl:ENSMUSG00000100711 +102634195 Gm31836 MGI:MGI:5590995 +102634197 Gm31838 MGI:MGI:5590997 +102634198 Gm31839 MGI:MGI:5590998 +102634199 Gm31840 MGI:MGI:5590999 +102634200 Gm31841 MGI:MGI:5591000 +102634201 Gm31842 MGI:MGI:5591001 +102634202 Gm31843 MGI:MGI:5591002 +102634203 Gm31844 MGI:MGI:5591003 +102634204 Gm31845 MGI:MGI:5591004 +102634205 Gm13264 MGI:MGI:3652184|Ensembl:ENSMUSG00000085257 +102634207 Gm31847 MGI:MGI:5591006 +102634208 Gm31848 MGI:MGI:5591007 +102634209 Gm31849 MGI:MGI:5591008 +102634210 Gm31850 MGI:MGI:5591009 +102634211 Gm13990 MGI:MGI:3651766 +102634212 Gm31851 MGI:MGI:5591010 +102634213 Gm31852 MGI:MGI:5591011 +102634215 Gm31854 MGI:MGI:5591013 +102634216 Gm31855 MGI:MGI:5591014 +102634217 LOC102634217 - +102634218 Gm25404 MGI:MGI:5455181 +102634220 Gm31857 MGI:MGI:5591016 +102634221 Gm31858 MGI:MGI:5591017 +102634222 Gm17467 MGI:MGI:4937101 +102634224 Gm28829 MGI:MGI:5579535 +102634227 Gm31860 MGI:MGI:5591019 +102634228 Gm31861 MGI:MGI:5591020 +102634229 Gm31862 MGI:MGI:5591021 +102634230 Gm31863 MGI:MGI:5591022 +102634232 Gm31865 MGI:MGI:5591024 +102634233 Gm38461 MGI:MGI:5621346 +102634234 Gm31866 MGI:MGI:5591025 +102634235 Gm31867 MGI:MGI:5591026 +102634236 Gm31868 MGI:MGI:5591027 +102634237 Gm31869 MGI:MGI:5591028 +102634238 Gm31870 MGI:MGI:5591029 +102634239 Gm31871 MGI:MGI:5591030 +102634240 Gm31872 MGI:MGI:5591031 +102634242 Gm31874 MGI:MGI:5591033 +102634243 Gm31875 MGI:MGI:5591034 +102634244 Platr16 MGI:MGI:3651931 +102634246 Gm31877 MGI:MGI:5591036 +102634247 Gm31878 MGI:MGI:5591037 +102634248 Gm28581 MGI:MGI:5579287 +102634249 Gm31879 MGI:MGI:5591038 +102634250 Gm31880 MGI:MGI:5591039 +102634251 Gm31881 MGI:MGI:5591040 +102634252 Gm31882 MGI:MGI:5591041 +102634254 Gm31884 MGI:MGI:5591043 +102634255 Gm21729 MGI:MGI:5433893 +102634258 Gm31887 MGI:MGI:5591046 +102634259 LOC102634259 - +102634260 Gm28423 MGI:MGI:5579129 +102634261 Gm31888 MGI:MGI:5591047 +102634262 Gm31889 MGI:MGI:5591048 +102634263 Gm31890 MGI:MGI:5591049 +102634264 Gm31891 MGI:MGI:5591050 +102634265 Gm31892 MGI:MGI:5591051 +102634266 Gm31893 MGI:MGI:5591052 +102634267 Gm31894 MGI:MGI:5591053 +102634268 LOC102634268 - +102634269 Gm31895 MGI:MGI:5591054 +102634271 Gm31896 MGI:MGI:5591055 +102634273 Gm31897 MGI:MGI:5591056 +102634274 Gm31898 MGI:MGI:5591057 +102634275 Gm29539 MGI:MGI:5580245 +102634276 Gm31899 MGI:MGI:5591058 +102634277 Gm31900 MGI:MGI:5591059 +102634278 Gm31901 MGI:MGI:5591060 +102634279 Gm31902 MGI:MGI:5591061 +102634280 Gm13486 MGI:MGI:3651420 +102634281 Gm31903 MGI:MGI:5591062 +102634282 Gm31904 MGI:MGI:5591063 +102634283 Gm31905 MGI:MGI:5591064 +102634284 Gm38462 MGI:MGI:5621347 +102634285 Gm31906 MGI:MGI:5591065 +102634286 Gm31907 MGI:MGI:5591066 +102634287 Gm31908 MGI:MGI:5591067 +102634288 Gm31909 MGI:MGI:5591068 +102634291 Gm31912 MGI:MGI:5591071 +102634292 Gm31913 MGI:MGI:5591072 +102634293 Gm31914 MGI:MGI:5591073 +102634295 Gm16189 MGI:MGI:3801760 +102634296 LOC102634296 Ensembl:ENSMUSG00000045010|Vega:OTTMUSG00000018191 +102634299 Gm31918 MGI:MGI:5591077 +102634300 LOC102634300 - +102634302 Gm27199 MGI:MGI:5521042|Ensembl:ENSMUSG00000098649 +102634303 Gm31920 MGI:MGI:5591079 +102634304 LOC102634304 - +102634305 Gm31921 MGI:MGI:5591080 +102634307 Gm12235 MGI:MGI:3650666 +102634308 Gm31923 MGI:MGI:5591082 +102634309 Gm11419 MGI:MGI:3651781 +102634310 Gm28783 MGI:MGI:5579489 +102634311 Gm31924 MGI:MGI:5591083 +102634312 LOC102634312 - +102634315 Gm31925 MGI:MGI:5591084 +102634316 Gm31926 MGI:MGI:5591085 +102634318 Gm31928 MGI:MGI:5591087 +102634321 Gm31930 MGI:MGI:5591089 +102634322 Gm31931 MGI:MGI:5591090 +102634323 Gm14320 MGI:MGI:3649455 +102634324 LOC102634324 - +102634325 Gm31933 MGI:MGI:5591092 +102634328 Gm31936 MGI:MGI:5591095 +102634329 Gm31937 MGI:MGI:5591096 +102634330 Gm31938 MGI:MGI:5591097|Ensembl:ENSMUSG00000112422 +102634331 Gm31939 MGI:MGI:5591098 +102634332 Gm31940 MGI:MGI:5591099 +102634333 LOC102634333 Ensembl:ENSMUSG00000090066|Vega:OTTMUSG00000035102 +102634334 Gm31941 MGI:MGI:5591100 +102634335 Gm31942 MGI:MGI:5591101 +102634336 Gm12650 MGI:MGI:3649946 +102634339 Gm31945 MGI:MGI:5591104 +102634340 LOC102634340 - +102634341 Gm31946 MGI:MGI:5591105 +102634342 Gm31947 MGI:MGI:5591106 +102634346 Gm31951 MGI:MGI:5591110 +102634348 LOC102634348 - +102634349 Gm38463 MGI:MGI:5621348 +102634350 LOC102634350 - +102634351 Gm31953 MGI:MGI:5591112 +102634353 Gm31954 MGI:MGI:5591113 +102634354 Gm31955 MGI:MGI:5591114 +102634355 Gm31956 MGI:MGI:5591115 +102634356 Gm31957 MGI:MGI:5591116 +102634357 Gm31958 MGI:MGI:5591117 +102634359 Gm29340 MGI:MGI:5580046 +102634360 Gm31960 MGI:MGI:5591119 +102634362 Gm31962 MGI:MGI:5591121 +102634363 Gm31963 MGI:MGI:5591122 +102634365 Gm31965 MGI:MGI:5591124 +102634366 Gm31966 MGI:MGI:5591125 +102634367 Gm29043 MGI:MGI:5579749 +102634368 Gm31967 MGI:MGI:5591126 +102634370 Gm29373 MGI:MGI:5580079 +102634371 Gm21749 MGI:MGI:5433913 +102634373 Gm31970 MGI:MGI:5591129 +102634376 Gm23952 MGI:MGI:5453729 +102634377 Gm31973 MGI:MGI:5591132 +102634378 Gm31974 MGI:MGI:5591133 +102634380 Gm31976 MGI:MGI:5591135 +102634381 Gm31977 MGI:MGI:5591136 +102634382 Gm31978 MGI:MGI:5591137 +102634383 Gm31979 MGI:MGI:5591138 +102634384 Gm31980 MGI:MGI:5591139 +102634385 Gm31981 MGI:MGI:5591140 +102634387 Gm31982 MGI:MGI:5591141 +102634388 LOC102634388 - +102634389 LOC102634389 Ensembl:ENSMUSG00000078648 +102634391 Gm31983 MGI:MGI:5591142 +102634392 Gm31984 MGI:MGI:5591143 +102634393 Gm31985 MGI:MGI:5591144 +102634394 Gm31986 MGI:MGI:5591145 +102634395 Gm31987 MGI:MGI:5591146 +102634396 Gm31988 MGI:MGI:5591147 +102634397 Gm31989 MGI:MGI:5591148 +102634398 Gm31990 MGI:MGI:5591149 +102634400 Gm31992 MGI:MGI:5591151 +102634401 LOC102634401 Ensembl:ENSMUSG00000085015 +102634402 Gm31993 MGI:MGI:5591152 +102634405 Gm13133 MGI:MGI:3650642 +102634406 Gm22043 MGI:MGI:5451820 +102634407 Gm24576 MGI:MGI:5454353 +102634408 Gm31996 MGI:MGI:5591155 +102634410 Gm31998 MGI:MGI:5591157 +102634411 Gm31999 MGI:MGI:5591158 +102634413 Gm29218 MGI:MGI:5579924 +102634415 Gm29503 MGI:MGI:5580209 +102634417 Gm32002 MGI:MGI:5591161 +102634418 Gm32003 MGI:MGI:5591162 +102634419 Gm32004 MGI:MGI:5591163 +102634420 Gm32005 MGI:MGI:5591164 +102634421 Gm32006 MGI:MGI:5591165 +102634422 Gm32007 MGI:MGI:5591166 +102634423 Gm32008 MGI:MGI:5591167 +102634424 Gm32009 MGI:MGI:5591168 +102634425 Gm32010 MGI:MGI:5591169 +102634426 Gm32011 MGI:MGI:5591170 +102634427 Gm32012 MGI:MGI:5591171 +102634428 Gm32013 MGI:MGI:5591172 +102634429 LOC102634429 - +102634431 Gm32014 MGI:MGI:5591173|Ensembl:ENSMUSG00000111602 +102634432 Gm32015 MGI:MGI:5591174 +102634433 Gm32016 MGI:MGI:5591175 +102634434 Gm32017 MGI:MGI:5591176 +102634435 Gm32018 MGI:MGI:5591177 +102634437 Ywhaq-ps3 MGI:MGI:3650241 +102634438 Gm32020 MGI:MGI:5591179 +102634439 Gm38464 MGI:MGI:5621349 +102634441 Gm32022 MGI:MGI:5591181 +102634442 Gm32023 MGI:MGI:5591182 +102634443 Gm32024 MGI:MGI:5591183 +102634444 Gm32025 MGI:MGI:5591184 +102634445 Gm32026 MGI:MGI:5591185 +102634446 Gm32027 MGI:MGI:5591186 +102634447 Gm32028 MGI:MGI:5591187 +102634448 Gm32029 MGI:MGI:5591188 +102634450 Gm32031 MGI:MGI:5591190|Ensembl:ENSMUSG00000109118 +102634451 Ndufab1-ps MGI:MGI:4936891 +102634453 Gm32033 MGI:MGI:5591192 +102634455 Gm32035 MGI:MGI:5591194 +102634456 Gm32036 MGI:MGI:5591195 +102634458 Gm28422 MGI:MGI:5579128|Ensembl:ENSMUSG00000099636 +102634459 LOC102634459 - +102634460 Gm32038 MGI:MGI:5591197 +102634461 Gm32039 MGI:MGI:5591198 +102634462 Gm38465 MGI:MGI:5621350 +102634463 Gm32040 MGI:MGI:5591199 +102634464 Gm32041 MGI:MGI:5591200 +102634465 Gm32042 MGI:MGI:5591201 +102634468 Gm32045 MGI:MGI:5591204 +102634469 Gm32046 MGI:MGI:5591205 +102634471 Gm32048 MGI:MGI:5591207 +102634472 Gm32049 MGI:MGI:5591208 +102634473 Gm29669 MGI:MGI:5580375|Ensembl:ENSMUSG00000100371 +102634474 Gm32050 MGI:MGI:5591209 +102634475 Gm32051 MGI:MGI:5591210|Ensembl:ENSMUSG00000106438 +102634476 Gm32052 MGI:MGI:5591211|Ensembl:ENSMUSG00000110624 +102634480 Gm32055 MGI:MGI:5591214 +102634481 LOC102634481 - +102634482 Gm32056 MGI:MGI:5591215 +102634483 LOC102634483 - +102634484 Gm32057 MGI:MGI:5591216 +102634485 Gm32058 MGI:MGI:5591217 +102634486 Gm38466 MGI:MGI:5621351 +102634487 Gm32059 MGI:MGI:5591218 +102634488 Gm28583 MGI:MGI:5579289 +102634490 Gm32061 MGI:MGI:5591220|Ensembl:ENSMUSG00000108986 +102634491 Gm32062 MGI:MGI:5591221 +102634492 Gm28314 MGI:MGI:5579020 +102634493 Gm28827 MGI:MGI:5579533 +102634494 Gm32063 MGI:MGI:5591222 +102634495 LOC102634495 - +102634496 Gm32064 MGI:MGI:5591223 +102634499 LOC102634499 - +102634500 Gm32067 MGI:MGI:5591226 +102634501 Gm32068 MGI:MGI:5591227 +102634502 2900060L22Rik MGI:MGI:1920261 +102634503 Gm32069 MGI:MGI:5591228 +102634504 Gm32070 MGI:MGI:5591229 +102634505 Gm32071 MGI:MGI:5591230 +102634506 Gm32072 MGI:MGI:5591231 +102634507 Gm32073 MGI:MGI:5591232 +102634509 Gm32074 MGI:MGI:5591233 +102634510 Gm32075 MGI:MGI:5591234 +102634511 Gm32076 MGI:MGI:5591235 +102634512 Gm13791 MGI:MGI:3650954 +102634513 Gm13982 MGI:MGI:3651941|Ensembl:ENSMUSG00000085681 +102634514 Gm32077 MGI:MGI:5591236 +102634516 Gm32079 MGI:MGI:5591238 +102634517 Gm13110 MGI:MGI:3651716 +102634519 Gm32080 MGI:MGI:5591239 +102634520 Gm32081 MGI:MGI:5591240 +102634521 Gm32082 MGI:MGI:5591241 +102634522 Gm32083 MGI:MGI:5591242 +102634523 Gm32084 MGI:MGI:5591243 +102634524 Gm32085 MGI:MGI:5591244 +102634525 Gm38467 MGI:MGI:5621352 +102634529 LOC102634529 - +102634530 Gm32089 MGI:MGI:5591248 +102634531 Gm32090 MGI:MGI:5591249 +102634532 Gm3642 MGI:MGI:3781818|Ensembl:ENSMUSG00000096685 +102634533 LOC102634533 Ensembl:ENSMUSG00000079467 +102634534 Gm32091 MGI:MGI:5591250 +102634535 Gm32092 MGI:MGI:5591251 +102634536 Gm32093 MGI:MGI:5591252 +102634539 Gm12236 MGI:MGI:3651548 +102634541 Gm28784 MGI:MGI:5579490 +102634543 Gm29128 MGI:MGI:5579834 +102634544 Gm32098 MGI:MGI:5591257 +102634545 Gm32099 MGI:MGI:5591258 +102634546 Gm32100 MGI:MGI:5591259 +102634547 Gm32101 MGI:MGI:5591260 +102634548 Gm32102 MGI:MGI:5591261 +102634550 Gm27166 MGI:MGI:5521009|Ensembl:ENSMUSG00000098519 +102634551 Gm32104 MGI:MGI:5591263 +102634553 Gm32105 MGI:MGI:5591264 +102634555 Gm32107 MGI:MGI:5591266 +102634556 Gm32108 MGI:MGI:5591267 +102634557 Gm16219 MGI:MGI:3802165 +102634559 Gm29443 MGI:MGI:5580149|Ensembl:ENSMUSG00000100583 +102634560 Gm32110 MGI:MGI:5591269 +102634561 Gm14377 MGI:MGI:3651179 +102634562 Gm32111 MGI:MGI:5591270 +102634563 Gm32112 MGI:MGI:5591271 +102634564 Gm32113 MGI:MGI:5591272 +102634565 Gm29048 MGI:MGI:5579754 +102634566 Gm32114 MGI:MGI:5591273 +102634568 Gm32116 MGI:MGI:5591275 +102634569 Gm32117 MGI:MGI:5591276 +102634570 Gm28790 MGI:MGI:5579496 +102634572 Gm32119 MGI:MGI:5591278 +102634574 Gm32121 MGI:MGI:5591280 +102634575 Gm32122 MGI:MGI:5591281|Ensembl:ENSMUSG00000110633 +102634576 Gm32123 MGI:MGI:5591282 +102634578 Gm32124 MGI:MGI:5591283 +102634579 Gm32125 MGI:MGI:5591284 +102634580 Gm26519 MGI:MGI:5477013|Ensembl:ENSMUSG00000097237 +102634581 LOC102634581 - +102634582 Gm32126 MGI:MGI:5591285 +102634584 LOC102634584 - +102634586 Gm32128 MGI:MGI:5591287 +102634588 Gm32130 MGI:MGI:5591289 +102634589 Gm32131 MGI:MGI:5591290 +102634592 Gm32133 MGI:MGI:5591292 +102634594 Gm32135 MGI:MGI:5591294 +102634596 Gm32137 MGI:MGI:5591296 +102634598 Gm32139 MGI:MGI:5591298 +102634599 Gm32140 MGI:MGI:5591299 +102634600 Gm32141 MGI:MGI:5591300|Ensembl:ENSMUSG00000112344 +102634601 Gm32142 MGI:MGI:5591301 +102634602 Gm32143 MGI:MGI:5591302 +102634603 Gm32144 MGI:MGI:5591303 +102634605 Gm32146 MGI:MGI:5591305 +102634607 Gm32148 MGI:MGI:5591307 +102634608 Gm16559 MGI:MGI:4414979 +102634610 Gm32150 MGI:MGI:5591309 +102634611 Gm32151 MGI:MGI:5591310 +102634616 Gm32156 MGI:MGI:5591315 +102634617 Gm29486 MGI:MGI:5580192 +102634619 Gm32158 MGI:MGI:5591317 +102634620 Gm32159 MGI:MGI:5591318 +102634623 Gm32162 MGI:MGI:5591321 +102634625 Gm32164 MGI:MGI:5591323 +102634628 Gm11418 MGI:MGI:3651780 +102634629 Gm32167 MGI:MGI:5591326 +102634630 Gm32168 MGI:MGI:5591327 +102634633 Gm32171 MGI:MGI:5591330 +102634634 Gm20491 MGI:MGI:5141956 +102634635 Gm32172 MGI:MGI:5591331|Ensembl:ENSMUSG00000112172 +102634636 Gm32173 MGI:MGI:5591332 +102634637 Gm32174 MGI:MGI:5591333 +102634638 Gm32175 MGI:MGI:5591334 +102634639 Gm32176 MGI:MGI:5591335 +102634640 Gm28806 MGI:MGI:5579512 +102634641 Gm32177 MGI:MGI:5591336 +102634642 Gm32178 MGI:MGI:5591337 +102634644 Gm32180 MGI:MGI:5591339 +102634645 Gm32181 MGI:MGI:5591340 +102634646 Gm12915 MGI:MGI:3650273 +102634647 Gm29370 MGI:MGI:5580076 +102634649 Gm32183 MGI:MGI:5591342 +102634650 Gm32184 MGI:MGI:5591343 +102634651 Gm32185 MGI:MGI:5591344 +102634652 Gm32186 MGI:MGI:5591345 +102634653 Gm32187 MGI:MGI:5591346 +102634656 Gm32190 MGI:MGI:5591349 +102634657 Gm32191 MGI:MGI:5591350 +102634658 Gm27198 MGI:MGI:5521041 +102634659 Gm32192 MGI:MGI:5591351 +102634661 Gm28178 MGI:MGI:5578884|Ensembl:ENSMUSG00000099878 +102634662 Gm32194 MGI:MGI:5591353 +102634664 Gm32196 MGI:MGI:5591355 +102634665 Gm32197 MGI:MGI:5591356 +102634667 Gm32199 MGI:MGI:5591358 +102634668 Gm32200 MGI:MGI:5591359 +102634669 Gm32201 MGI:MGI:5591360 +102634670 Gm32202 MGI:MGI:5591361 +102634671 Gm32203 MGI:MGI:5591362 +102634672 Gm32204 MGI:MGI:5591363 +102634676 Gm32208 MGI:MGI:5591367 +102634677 Gm32209 MGI:MGI:5591368 +102634678 Haglr MGI:MGI:3026978 +102634679 Gm32210 MGI:MGI:5591369 +102634680 Gm14210 MGI:MGI:3651323 +102634681 Gm32211 MGI:MGI:5591370 +102634683 LOC102634683 - +102634684 Gm32213 MGI:MGI:5591372 +102634685 Gm17197 MGI:MGI:4938024 +102634686 Gm32214 MGI:MGI:5591373 +102634688 Gm32216 MGI:MGI:5591375 +102634690 Gm28098 MGI:MGI:5578804 +102634692 Gm32219 MGI:MGI:5591378 +102634693 Gm32220 MGI:MGI:5591379 +102634694 Gm21868 MGI:MGI:5434032 +102634695 Gm29624 MGI:MGI:5580330 +102634696 Gm28302 MGI:MGI:5579008 +102634697 Gm15984 MGI:MGI:3802050 +102634698 Gm32221 MGI:MGI:5591380 +102634700 Gm32222 MGI:MGI:5591381 +102634701 Gm32223 MGI:MGI:5591382 +102634702 Gm32224 MGI:MGI:5591383 +102634705 Gm32226 MGI:MGI:5591385 +102634706 Gm32227 MGI:MGI:5591386 +102634708 Gm11695 MGI:MGI:3649841 +102634709 LOC102634709 Ensembl:ENSMUSG00000061848 +102634710 Gm32229 MGI:MGI:5591388 +102634711 Gm32230 MGI:MGI:5591389 +102634712 Gm32231 MGI:MGI:5591390 +102634713 Gm32232 MGI:MGI:5591391 +102634715 Gm32234 MGI:MGI:5591393 +102634716 LOC102634716 - +102634717 Gm32235 MGI:MGI:5591394 +102634718 Gm32236 MGI:MGI:5591395 +102634719 Gm32237 MGI:MGI:5591396 +102634721 Gm32239 MGI:MGI:5591398 +102634722 Gm32240 MGI:MGI:5591399 +102634723 Gm32241 MGI:MGI:5591400 +102634724 Gm32242 MGI:MGI:5591401 +102634725 Gm32243 MGI:MGI:5591402 +102634726 Gm29012 MGI:MGI:5579718 +102634727 Gm29485 MGI:MGI:5580191 +102634729 Gm26970 MGI:MGI:5504085 +102634730 LOC102634730 - +102634732 Gm32245 MGI:MGI:5591404 +102634733 LOC102634733 - +102634734 Gm32246 MGI:MGI:5591405 +102634735 Gm32247 MGI:MGI:5591406 +102634737 Gm32249 MGI:MGI:5591408 +102634738 Gm28154 MGI:MGI:5578860|Ensembl:ENSMUSG00000100053 +102634739 Gm32250 MGI:MGI:5591409 +102634740 Gm32251 MGI:MGI:5591410 +102634741 Gm15341 MGI:MGI:3705258 +102634742 Gm26631 MGI:MGI:5477125 +102634743 Gm32252 MGI:MGI:5591411 +102634745 LOC102634745 - +102634746 Gm13201 MGI:MGI:3649941 +102634748 Gm32255 MGI:MGI:5591414 +102634749 Gm32256 MGI:MGI:5591415 +102634750 Gm32257 MGI:MGI:5591416 +102634751 Gm32258 MGI:MGI:5591417 +102634752 Gm32259 MGI:MGI:5591418 +102634753 Gm12440 MGI:MGI:3649266|Ensembl:ENSMUSG00000086833 +102634755 Gm32261 MGI:MGI:5591420 +102634756 Gm32262 MGI:MGI:5591421 +102634757 Gm32263 MGI:MGI:5591422 +102634758 Gm32264 MGI:MGI:5591423 +102634759 Gm32265 MGI:MGI:5591424 +102634760 Gm21751 MGI:MGI:5433915 +102634761 Gm32266 MGI:MGI:5591425 +102634762 Gm32267 MGI:MGI:5591426 +102634764 Gm32268 MGI:MGI:5591427 +102634765 Gm32269 MGI:MGI:5591428 +102634767 Gm32271 MGI:MGI:5591430 +102634768 Gm32272 MGI:MGI:5591431 +102634769 Gm32273 MGI:MGI:5591432 +102634772 Gm32275 MGI:MGI:5591434 +102634773 Gm32276 MGI:MGI:5591435 +102634774 Gm32277 MGI:MGI:5591436 +102634775 Gm32278 MGI:MGI:5591437 +102634776 Gm32279 MGI:MGI:5591438 +102634777 Gm13266 MGI:MGI:3652181|Ensembl:ENSMUSG00000084901 +102634778 Gm32280 MGI:MGI:5591439 +102634779 Gm32281 MGI:MGI:5591440 +102634780 Gm32282 MGI:MGI:5591441 +102634781 Gm32283 MGI:MGI:5591442 +102634782 Gm32284 MGI:MGI:5591443 +102634783 Gm11228 MGI:MGI:3651435|Ensembl:ENSMUSG00000084937 +102634785 Gm32286 MGI:MGI:5591445 +102634786 Gm32287 MGI:MGI:5591446 +102634787 Gm32288 MGI:MGI:5591447 +102634788 Gm32289 MGI:MGI:5591448 +102634790 Gm32291 MGI:MGI:5591450 +102634792 Gm32293 MGI:MGI:5591452 +102634793 Gm32294 MGI:MGI:5591453 +102634794 Gm32295 MGI:MGI:5591454 +102634795 Gm32296 MGI:MGI:5591455 +102634796 Gm32297 MGI:MGI:5591456 +102634798 Gm32298 MGI:MGI:5591457 +102634800 Gm32300 MGI:MGI:5591459 +102634801 Gm28837 MGI:MGI:5579543 +102634803 Gm32302 MGI:MGI:5591461 +102634805 LOC102634805 - +102634806 Gm32304 MGI:MGI:5591463 +102634807 Gm32305 MGI:MGI:5591464 +102634809 Gm32307 MGI:MGI:5591466 +102634810 Gm32308 MGI:MGI:5591467 +102634811 Gm32309 MGI:MGI:5591468 +102634812 LOC102634812 - +102634813 Gm32310 MGI:MGI:5591469 +102634814 Gm26788 MGI:MGI:5477282 +102634815 Gm32311 MGI:MGI:5591470 +102634817 Gm32312 MGI:MGI:5591471 +102634818 Gm32313 MGI:MGI:5591472 +102634820 Gm32315 MGI:MGI:5591474 +102634821 Gm32316 MGI:MGI:5591475 +102634822 Gm11131 MGI:MGI:3779386 +102634823 Gm32317 MGI:MGI:5591476 +102634825 Gm32319 MGI:MGI:5591478 +102634826 Gm32320 MGI:MGI:5591479 +102634827 Gm38468 MGI:MGI:5621353 +102634829 Gm28780 MGI:MGI:5579486 +102634830 Gm32322 MGI:MGI:5591481 +102634835 LOC102634835 - +102634836 Gm32327 MGI:MGI:5591486 +102634837 Gm13853 MGI:MGI:3649279 +102634838 Gm32328 MGI:MGI:5591487 +102634839 Gm26666 MGI:MGI:5477160 +102634841 Gm38469 MGI:MGI:5621354 +102634842 Gm32330 MGI:MGI:5591489 +102634843 Gm32331 MGI:MGI:5591490 +102634844 Gm16582 MGI:MGI:4415002 +102634846 Gm32333 MGI:MGI:5591492 +102634847 Gm32334 MGI:MGI:5591493 +102634848 Gm32335 MGI:MGI:5591494 +102634849 Gm32336 MGI:MGI:5591495 +102634850 Gm32337 MGI:MGI:5591496 +102634851 Gm32338 MGI:MGI:5591497 +102634852 LOC102634852 Ensembl:ENSMUSG00000066141|Vega:OTTMUSG00000000276 +102634853 Gm13652 MGI:MGI:3650033 +102634854 LOC102634854 - +102634855 Gm32339 MGI:MGI:5591498 +102634856 Gm32340 MGI:MGI:5591499 +102634857 Gm32341 MGI:MGI:5591500 +102634858 Gm32342 MGI:MGI:5591501 +102634859 Gm32343 MGI:MGI:5591502 +102634860 Gm32344 MGI:MGI:5591503 +102634861 Gm38470 MGI:MGI:5621355 +102634862 Gm32345 MGI:MGI:5591504 +102634864 Gm32347 MGI:MGI:5591506 +102634865 Gm32348 MGI:MGI:5591507 +102634866 Gm28765 MGI:MGI:5579471 +102634868 Gm32350 MGI:MGI:5591509 +102634869 Gm32351 MGI:MGI:5591510 +102634871 Gm32352 MGI:MGI:5591511 +102634872 LOC102634872 - +102634873 LOC102634873 - +102634874 Gm32353 MGI:MGI:5591512 +102634876 Gm27228 MGI:MGI:5521071 +102634877 Gm32355 MGI:MGI:5591514 +102634878 Gm32356 MGI:MGI:5591515 +102634879 Gm15715 MGI:MGI:3783157 +102634880 Gm32357 MGI:MGI:5591516 +102634881 Gm32358 MGI:MGI:5591517 +102634882 Gm32359 MGI:MGI:5591518 +102634883 Gm32360 MGI:MGI:5591519 +102634885 Gm32362 MGI:MGI:5591521 +102634886 Gm32363 MGI:MGI:5591522 +102634887 LOC102634887 - +102634888 Gm32364 MGI:MGI:5591523 +102634889 Gm32365 MGI:MGI:5591524 +102634891 Scgb2b28-ps MGI:MGI:5578752 +102634892 Gm32367 MGI:MGI:5591526 +102634893 Gm32368 MGI:MGI:5591527 +102634894 Gm32369 MGI:MGI:5591528 +102634895 Gm32370 MGI:MGI:5591529 +102634896 Gm32371 MGI:MGI:5591530 +102634898 Gm32373 MGI:MGI:5591532 +102634899 Gm32374 MGI:MGI:5591533 +102634900 LOC102634900 - +102634902 Gm32376 MGI:MGI:5591535 +102634903 Gm32377 MGI:MGI:5591536 +102634904 LOC102634904 - +102634905 Gm32378 MGI:MGI:5591537 +102634906 Gm32379 MGI:MGI:5591538 +102634907 Gm32380 MGI:MGI:5591539 +102634908 Gm32381 MGI:MGI:5591540 +102634909 Gm32382 MGI:MGI:5591541 +102634910 Gm32383 MGI:MGI:5591542 +102634911 Gm32384 MGI:MGI:5591543 +102634912 Gm32385 MGI:MGI:5591544 +102634913 Gm16070 MGI:MGI:3801761|Ensembl:ENSMUSG00000085125 +102634915 Gm12268 MGI:MGI:3702435 +102634918 Gm38471 MGI:MGI:5621356 +102634919 Gm32389 MGI:MGI:5591548 +102634920 Gm29228 MGI:MGI:5579934 +102634921 Gm32390 MGI:MGI:5591549 +102634922 Gm32391 MGI:MGI:5591550 +102634923 Gm32392 MGI:MGI:5591551 +102634924 LOC102634924 - +102634926 Gm12426 MGI:MGI:3650989 +102634927 Gm32394 MGI:MGI:5591553 +102634928 Gm32395 MGI:MGI:5591554 +102634931 Gm32398 MGI:MGI:5591557 +102634933 Gm26871 MGI:MGI:5477365 +102634934 Gm32399 MGI:MGI:5591558 +102634936 Gm21810 MGI:MGI:5433974 +102634937 Gm29166 MGI:MGI:5579872 +102634938 Gm28350 MGI:MGI:5579056 +102634939 Gm28789 MGI:MGI:5579495 +102634940 Gm32401 MGI:MGI:5591560 +102634941 Gm29376 MGI:MGI:5580082 +102634943 Gm32403 MGI:MGI:5591562 +102634944 Gm32404 MGI:MGI:5591563 +102634945 Gm32405 MGI:MGI:5591564 +102634946 Gm32406 MGI:MGI:5591565 +102634949 Gm13269 MGI:MGI:3651949 +102634950 Gm32409 MGI:MGI:5591568 +102634952 Gm32411 MGI:MGI:5591570 +102634953 Gm32412 MGI:MGI:5591571 +102634954 Gm32413 MGI:MGI:5591572 +102634955 Gm32414 MGI:MGI:5591573 +102634956 LOC102634956 - +102634958 Gm32416 MGI:MGI:5591575 +102634959 Gm15926 MGI:MGI:3801890 +102634962 Gm27252 MGI:MGI:5521095 +102634963 Gm32419 MGI:MGI:5591578 +102634964 Gm24474 MGI:MGI:5454251 +102634965 Gm29027 MGI:MGI:5579733|Ensembl:ENSMUSG00000100647 +102634966 Gm32420 MGI:MGI:5591579 +102634967 Gm16341 MGI:MGI:3840137 +102634968 LOC102634968 - +102634970 Gm32422 MGI:MGI:5591581 +102634971 Gm32423 MGI:MGI:5591582 +102634973 Gm32425 MGI:MGI:5591584 +102634974 Gm32426 MGI:MGI:5591585 +102634976 Gm32427 MGI:MGI:5591586 +102634978 Gm32428 MGI:MGI:5591587 +102634979 Gm27150 MGI:MGI:5520993 +102634980 Gm32429 MGI:MGI:5591588 +102634981 Gm32430 MGI:MGI:5591589 +102634982 Gm32431 MGI:MGI:5591590 +102634983 Gm32432 MGI:MGI:5591591 +102634985 Gm32434 MGI:MGI:5591593 +102634986 Gm32435 MGI:MGI:5591594 +102634987 Gm32436 MGI:MGI:5591595 +102634988 Gm32437 MGI:MGI:5591596 +102634989 Gm32438 MGI:MGI:5591597 +102634990 Gm32439 MGI:MGI:5591598 +102634991 Gm32440 MGI:MGI:5591599 +102634992 Gm32441 MGI:MGI:5591600 +102634993 Gm32442 MGI:MGI:5591601 +102634994 Gm32443 MGI:MGI:5591602 +102634995 Gm32444 MGI:MGI:5591603 +102634998 Gm32447 MGI:MGI:5591606 +102634999 LOC102634999 - +102635000 Gm28194 MGI:MGI:5578900 +102635001 Gm29181 MGI:MGI:5579887 +102635002 Gm28301 MGI:MGI:5579007|Ensembl:ENSMUSG00000099399 +102635003 Gm32448 MGI:MGI:5591607 +102635004 Gm32449 MGI:MGI:5591608 +102635006 Gm32450 MGI:MGI:5591609 +102635008 Gm25432 MGI:MGI:5455209 +102635010 Gm32453 MGI:MGI:5591612 +102635011 Gm32454 MGI:MGI:5591613 +102635012 Gm32455 MGI:MGI:5591614 +102635013 Gm15825 MGI:MGI:3801887|Ensembl:ENSMUSG00000089787 +102635014 Gm32456 MGI:MGI:5591615 +102635015 Gm32457 MGI:MGI:5591616 +102635016 Gm28419 MGI:MGI:5579125 +102635017 Gm32458 MGI:MGI:5591617 +102635018 Gm32459 MGI:MGI:5591618 +102635019 Gm32460 MGI:MGI:5591619 +102635020 Gm32461 MGI:MGI:5591620 +102635021 Gm32462 MGI:MGI:5591621 +102635023 Gm32463 MGI:MGI:5591622 +102635024 Gm32464 MGI:MGI:5591623 +102635025 Gm32465 MGI:MGI:5591624 +102635027 Gm32467 MGI:MGI:5591626 +102635028 Gm32468 MGI:MGI:5591627 +102635029 Gm32469 MGI:MGI:5591628 +102635030 Gm16016 MGI:MGI:3802068 +102635031 Gm32470 MGI:MGI:5591629 +102635032 Gm32471 MGI:MGI:5591630 +102635033 Gm32472 MGI:MGI:5591631 +102635034 Gm32473 MGI:MGI:5591632 +102635035 Gm21805 MGI:MGI:5433969 +102635036 Gm38472 MGI:MGI:5621357 +102635037 Gm32474 MGI:MGI:5591633 +102635039 Gm32476 MGI:MGI:5591635 +102635040 Gm15637 MGI:MGI:3783081 +102635041 Gm32477 MGI:MGI:5591636 +102635042 Gm32478 MGI:MGI:5591637 +102635043 Gm32479 MGI:MGI:5591638 +102635044 Gm32480 MGI:MGI:5591639 +102635045 Gm32481 MGI:MGI:5591640 +102635046 Gm32482 MGI:MGI:5591641 +102635047 Gm32483 MGI:MGI:5591642 +102635048 LOC102635048 Ensembl:ENSMUSG00000082419 +102635050 Gm32485 MGI:MGI:5591644 +102635051 Gm32486 MGI:MGI:5591645 +102635052 Gm15279 MGI:MGI:3826582 +102635053 Gm16276 MGI:MGI:3826598 +102635054 Gm32487 MGI:MGI:5591646 +102635056 Gm32488 MGI:MGI:5591647 +102635057 Gm32489 MGI:MGI:5591648 +102635058 Gm32490 MGI:MGI:5591649 +102635059 Gm32491 MGI:MGI:5591650 +102635060 Gm32492 MGI:MGI:5591651 +102635063 Gm28944 MGI:MGI:5579650 +102635064 Gm32495 MGI:MGI:5591654 +102635065 Gm32496 MGI:MGI:5591655|Ensembl:ENSMUSG00000104102 +102635066 Gm32497 MGI:MGI:5591656 +102635067 LOC102635067 - +102635068 Gm24392 MGI:MGI:5454169 +102635069 Gm32498 MGI:MGI:5591657 +102635070 Gm32499 MGI:MGI:5591658 +102635071 Gm26944 MGI:MGI:5504059 +102635072 Gm32500 MGI:MGI:5591659 +102635073 Gm32501 MGI:MGI:5591660 +102635074 Gm32502 MGI:MGI:5591661 +102635077 Gm32503 MGI:MGI:5591662 +102635078 Gm32504 MGI:MGI:5591663 +102635079 Gm32505 MGI:MGI:5591664 +102635080 Gm32506 MGI:MGI:5591665 +102635081 Gm32507 MGI:MGI:5591666 +102635083 Gm26685 MGI:MGI:5477179|Ensembl:ENSMUSG00000097281 +102635084 Gm32508 MGI:MGI:5591667 +102635085 Gm32509 MGI:MGI:5591668 +102635086 Gm32510 MGI:MGI:5591669 +102635087 Gm32511 MGI:MGI:5591670|Ensembl:ENSMUSG00000111429 +102635088 Gm32512 MGI:MGI:5591671 +102635089 Gm38473 MGI:MGI:5621358 +102635090 Gm32513 MGI:MGI:5591672 +102635091 Gm32514 MGI:MGI:5591673 +102635092 Gm32515 MGI:MGI:5591674 +102635093 Gm32516 MGI:MGI:5591675 +102635094 Gm32517 MGI:MGI:5591676 +102635095 Gm32518 MGI:MGI:5591677 +102635097 Gm32520 MGI:MGI:5753146 +102635098 Gm29317 MGI:MGI:5580023 +102635099 Gm21916 MGI:MGI:5434080 +102635101 Gm32522 MGI:MGI:5591681 +102635102 Gm32523 MGI:MGI:5591682 +102635104 Gm32525 MGI:MGI:5591684 +102635105 Gm32526 MGI:MGI:5591685 +102635106 Gm29109 MGI:MGI:5579815 +102635107 Gm32527 MGI:MGI:5591686 +102635108 Gm32528 MGI:MGI:5591687 +102635109 Gm32529 MGI:MGI:5591688 +102635110 Gm32530 MGI:MGI:5591689 +102635111 Gm32531 MGI:MGI:5591690 +102635112 Gm32532 MGI:MGI:5591691 +102635113 Gm32533 MGI:MGI:5591692 +102635114 Gm32534 MGI:MGI:5591693 +102635115 Gm32535 MGI:MGI:5591694 +102635116 Gm32536 MGI:MGI:5591695 +102635117 Gm32537 MGI:MGI:5591696 +102635119 Gm32539 MGI:MGI:5591698 +102635120 Gm32540 MGI:MGI:5591699|Ensembl:ENSMUSG00000108961 +102635122 LOC102635122 - +102635123 Gm32542 MGI:MGI:5591701 +102635124 Gm32543 MGI:MGI:5591702 +102635125 Gm32544 MGI:MGI:5591703 +102635126 Gm32545 MGI:MGI:5591704 +102635128 Gm32546 MGI:MGI:5591705 +102635129 Gm32547 MGI:MGI:5591706 +102635130 Gm32548 MGI:MGI:5591707 +102635131 Gm32549 MGI:MGI:5591708 +102635133 LOC102635133 - +102635134 Gm32551 MGI:MGI:5591710 +102635135 Gm32552 MGI:MGI:5591711 +102635136 Gm26671 MGI:MGI:5477165|Ensembl:ENSMUSG00000097339 +102635137 Gm32553 MGI:MGI:5591712 +102635138 Gm38474 MGI:MGI:5621359 +102635139 Gm21755 MGI:MGI:5433919 +102635140 Gm28943 MGI:MGI:5579649 +102635141 Gm32554 MGI:MGI:5591713 +102635142 Gm32555 MGI:MGI:5591714 +102635143 Gm28626 MGI:MGI:5579332 +102635144 Gm32556 MGI:MGI:5591715 +102635146 Gm32558 MGI:MGI:5591717 +102635147 Gm32559 MGI:MGI:5591718 +102635148 Gm32560 MGI:MGI:5591719 +102635149 Gm32561 MGI:MGI:5591720 +102635150 Gm38475 MGI:MGI:5621360 +102635151 Gm32562 MGI:MGI:5591721 +102635152 Gm32563 MGI:MGI:5591722 +102635153 Gm15533 MGI:MGI:3782982 +102635154 LOC102635154 - +102635155 Gm32564 MGI:MGI:5591723 +102635156 Gm32565 MGI:MGI:5591724 +102635157 Gm32566 MGI:MGI:5591725 +102635158 Gm32567 MGI:MGI:5591726 +102635159 Gm32568 MGI:MGI:5591727 +102635160 Gm32569 MGI:MGI:5591728 +102635161 LOC102635161 - +102635163 Gm32571 MGI:MGI:5591730 +102635164 LOC102635164 - +102635165 LOC102635165 - +102635166 Gm32572 MGI:MGI:5591731 +102635167 Gm32573 MGI:MGI:5591732 +102635169 LOC102635169 - +102635170 Gm32574 MGI:MGI:5591733 +102635171 Gm32575 MGI:MGI:5591734 +102635172 Scgb1b8-ps MGI:MGI:5578747 +102635173 Gm32576 MGI:MGI:5591735 +102635174 Gm32577 MGI:MGI:5591736 +102635176 Gm32579 MGI:MGI:5591738 +102635178 Gm32581 MGI:MGI:5591740 +102635181 Gm32584 MGI:MGI:5591743 +102635182 Gm32585 MGI:MGI:5591744 +102635183 Gm32586 MGI:MGI:5591745 +102635184 Gm27572 MGI:MGI:5530954 +102635185 Gm32587 MGI:MGI:5591746 +102635186 Gm32588 MGI:MGI:5591747 +102635187 Gm32589 MGI:MGI:5591748 +102635188 Gm32590 MGI:MGI:5591749 +102635189 Gm32591 MGI:MGI:5591750|Ensembl:ENSMUSG00000108015 +102635190 Gm32592 MGI:MGI:5591751 +102635191 Gm16573 MGI:MGI:4414993 +102635192 Gm16835 MGI:MGI:4439759 +102635193 Gm32593 MGI:MGI:5591752 +102635194 Gm32594 MGI:MGI:5591753 +102635195 Gm32595 MGI:MGI:5591754 +102635196 Gm32596 MGI:MGI:5591755 +102635197 Gm32597 MGI:MGI:5591756 +102635198 Gm38476 MGI:MGI:5621361 +102635200 LOC102635200 - +102635202 Gm12436 MGI:MGI:3651705|Ensembl:ENSMUSG00000084787 +102635203 Gm32600 MGI:MGI:5591759 +102635206 Gm32603 MGI:MGI:5591762 +102635209 Gm32604 MGI:MGI:5591763 +102635210 Gm32605 MGI:MGI:5591764 +102635212 Gm32607 MGI:MGI:5591766 +102635213 Gm32608 MGI:MGI:5591767 +102635216 Gm32611 MGI:MGI:5591770 +102635218 Gm21869 MGI:MGI:5434033 +102635219 LOC102635219 - +102635220 Gm32613 MGI:MGI:5591772 +102635221 Gm32614 MGI:MGI:5591773 +102635223 Gm32616 MGI:MGI:5591775 +102635225 Gm15499 MGI:MGI:3782946 +102635226 Gm32618 MGI:MGI:5591777 +102635227 Gm32619 MGI:MGI:5591778 +102635228 Gm12318 MGI:MGI:3649449 +102635229 Gm32620 MGI:MGI:5591779 +102635230 Gm32621 MGI:MGI:5591780 +102635231 Gm32622 MGI:MGI:5591781 +102635232 Gm32623 MGI:MGI:5591782 +102635233 Gm32624 MGI:MGI:5591783 +102635237 Gm32627 MGI:MGI:5591786 +102635239 Gm32629 MGI:MGI:5591788 +102635240 Gm32630 MGI:MGI:5591789 +102635241 Gm32631 MGI:MGI:5591790 +102635242 Gm32632 MGI:MGI:5591791 +102635243 Gm32633 MGI:MGI:5591792 +102635244 Gm32634 MGI:MGI:5591793 +102635245 LOC102635245 - +102635246 Gm29330 MGI:MGI:5580036 +102635247 Gm32635 MGI:MGI:5591794 +102635248 Gm32636 MGI:MGI:5591795 +102635250 Gm21864 MGI:MGI:5434028 +102635252 LOC102635252 - +102635253 Gm32639 MGI:MGI:5591798 +102635254 Gm32640 MGI:MGI:5591799 +102635255 Gm32641 MGI:MGI:5591800 +102635256 Gm32642 MGI:MGI:5591801 +102635257 Gm32643 MGI:MGI:5591802 +102635258 Gm32644 MGI:MGI:5591803 +102635259 Gm32645 MGI:MGI:5591804 +102635260 Gm32646 MGI:MGI:5591805 +102635261 LOC102635261 - +102635262 Gm32647 MGI:MGI:5591806 +102635264 Gm32649 MGI:MGI:5591808 +102635265 Gm32650 MGI:MGI:5591809 +102635266 Gm32651 MGI:MGI:5591810 +102635268 Gm15738 MGI:MGI:3783180 +102635269 Gm32652 MGI:MGI:5591811 +102635270 Gm32653 MGI:MGI:5591812 +102635272 Gm32655 MGI:MGI:5591814 +102635273 LOC102635273 - +102635274 Gm32656 MGI:MGI:5591815 +102635275 Bach2it1 MGI:MGI:3651084 +102635276 Gm32657 MGI:MGI:5591816 +102635277 Gm32658 MGI:MGI:5591817 +102635278 Gm32659 MGI:MGI:5591818 +102635279 Gm32660 MGI:MGI:5591819 +102635280 Gm32661 MGI:MGI:5591820 +102635281 Gm32662 MGI:MGI:5591821 +102635283 Gm32663 MGI:MGI:5591822 +102635284 Gm29627 MGI:MGI:5580333 +102635286 Gm32664 MGI:MGI:5591823 +102635288 Gm32666 MGI:MGI:5591825 +102635290 Ttc39aos1 MGI:MGI:3651956 +102635292 Gm32669 MGI:MGI:5591828 +102635293 Gm32670 MGI:MGI:5591829 +102635295 Gm32672 MGI:MGI:5591831 +102635296 Gm32673 MGI:MGI:5591832 +102635298 Gm32675 MGI:MGI:5591834 +102635299 Gm32676 MGI:MGI:5591835 +102635300 Gm20501 MGI:MGI:5141966 +102635302 Gm32677 MGI:MGI:5591836 +102635303 Gm32678 MGI:MGI:5591837 +102635304 Gm29065 MGI:MGI:5579771 +102635305 Gm15991 MGI:MGI:3801813 +102635306 Gm32679 MGI:MGI:5591838 +102635307 Gm32680 MGI:MGI:5591839 +102635308 Gm32681 MGI:MGI:5591840 +102635309 Gm32682 MGI:MGI:5591841 +102635310 Gm32683 MGI:MGI:5591842 +102635311 Gm32684 MGI:MGI:5591843 +102635312 Gm32685 MGI:MGI:5591844 +102635315 Gm32687 MGI:MGI:5591846|Ensembl:ENSMUSG00000112640 +102635316 Gm32688 MGI:MGI:5591847|Ensembl:ENSMUSG00000111531 +102635317 Gm32689 MGI:MGI:5591848 +102635321 Gm32693 MGI:MGI:5591852|Ensembl:ENSMUSG00000106505 +102635322 LOC102635322 - +102635323 Gm32694 MGI:MGI:5591853 +102635324 Gm32695 MGI:MGI:5591854 +102635325 Gm21774 MGI:MGI:5433938 +102635326 Gm32696 MGI:MGI:5591855 +102635329 Gm28533 MGI:MGI:5579239 +102635331 Gm32699 MGI:MGI:5591858 +102635332 Gm28787 MGI:MGI:5579493 +102635333 Gm32700 MGI:MGI:5591859 +102635334 Gm15389 MGI:MGI:3705287|Ensembl:ENSMUSG00000086161 +102635335 Gm32701 MGI:MGI:5591860 +102635336 Gm32702 MGI:MGI:5591861 +102635337 Gm32703 MGI:MGI:5591862 +102635339 LOC102635339 - +102635340 Gm32705 MGI:MGI:5591864 +102635341 LOC102635341 - +102635342 LOC102635342 - +102635344 Gm32707 MGI:MGI:5591866 +102635345 Gm32708 MGI:MGI:5591867 +102635346 Gm32709 MGI:MGI:5591868 +102635347 Gm32710 MGI:MGI:5591869 +102635348 Gm32711 MGI:MGI:5591870 +102635349 Gm38477 MGI:MGI:5621362 +102635351 Gm32713 MGI:MGI:5591872 +102635352 Gm32714 MGI:MGI:5591873 +102635354 Gm32715 MGI:MGI:5591874 +102635355 Gm32716 MGI:MGI:5591875 +102635356 Gm14197 MGI:MGI:3652057 +102635357 Gm32717 MGI:MGI:5591876 +102635358 LOC102635358 - +102635359 Gm32718 MGI:MGI:5591877 +102635360 Gm32719 MGI:MGI:5591878 +102635361 Gm32720 MGI:MGI:5591879 +102635362 Gm32721 MGI:MGI:5591880 +102635363 Gm32722 MGI:MGI:5591881 +102635364 Gm32723 MGI:MGI:5591882 +102635365 Gm29023 MGI:MGI:5579729 +102635366 Gm32724 MGI:MGI:5591883 +102635367 Gm21802 MGI:MGI:5433966 +102635368 Gm32725 MGI:MGI:5591884 +102635369 Gm32726 MGI:MGI:5591885 +102635370 Gm32727 MGI:MGI:5591886 +102635371 Gm32728 MGI:MGI:5591887 +102635372 Gm32729 MGI:MGI:5591888 +102635373 Gm32730 MGI:MGI:5591889 +102635374 Gm32731 MGI:MGI:5591890 +102635376 Gm32733 MGI:MGI:5591892 +102635377 Gm32734 MGI:MGI:5591893 +102635378 Gm32735 MGI:MGI:5591894 +102635379 Gm32736 MGI:MGI:5591895 +102635380 Gm32737 MGI:MGI:5591896 +102635381 Gm32738 MGI:MGI:5591897 +102635382 Gm32739 MGI:MGI:5591898 +102635383 Gm32740 MGI:MGI:5591899 +102635384 Gm32741 MGI:MGI:5591900 +102635385 Gm32742 MGI:MGI:5591901|Ensembl:ENSMUSG00000110266|Vega:OTTMUSG00000061350 +102635386 LOC102635386 - +102635387 Gm32743 MGI:MGI:5591902 +102635389 LOC102635389 - +102635391 Gm32745 MGI:MGI:5591904 +102635392 Gm32746 MGI:MGI:5591905 +102635393 Gm32747 MGI:MGI:5591906 +102635395 Gm32748 MGI:MGI:5591907 +102635396 Gm32749 MGI:MGI:5591908 +102635397 Gm32750 MGI:MGI:5591909 +102635398 LOC102635398 - +102635400 Gm38478 MGI:MGI:5621363 +102635402 Gm32753 MGI:MGI:5591912 +102635403 Gm32754 MGI:MGI:5591913 +102635405 Gm32755 MGI:MGI:5591914 +102635406 Gm32756 MGI:MGI:5591915 +102635408 Gm32758 MGI:MGI:5591917 +102635409 LOC102635409 - +102635410 LOC102635410 - +102635412 Gm32759 MGI:MGI:5591918 +102635413 Gm32760 MGI:MGI:5591919 +102635415 Halr1 MGI:MGI:3705267|Ensembl:ENSMUSG00000085412 +102635416 Gm32762 MGI:MGI:5591921 +102635417 Gm32763 MGI:MGI:5591922 +102635418 Gm32764 MGI:MGI:5591923 +102635419 Gm32765 MGI:MGI:5591924 +102635420 Gm32766 MGI:MGI:5591925 +102635421 Gm11430 MGI:MGI:3649771 +102635423 LOC102635423 - +102635424 Gm32767 MGI:MGI:5591926 +102635425 Gm15553 MGI:MGI:3783002 +102635426 Gm32768 MGI:MGI:5591927 +102635427 Gm32769 MGI:MGI:5591928 +102635428 Gm26614 MGI:MGI:5477108 +102635429 Gm20655 MGI:MGI:5313102 +102635430 LOC102635430 - +102635431 Gm32770 MGI:MGI:5591929 +102635432 Gm32771 MGI:MGI:5591930 +102635433 Gm32772 MGI:MGI:5591931 +102635434 Gm32773 MGI:MGI:5591932 +102635437 Gm32776 MGI:MGI:5591935 +102635438 Gm32777 MGI:MGI:5591936 +102635439 LOC102635439 - +102635440 Gm21922 MGI:MGI:5434086 +102635441 Gm32778 MGI:MGI:5591937 +102635444 Gm32780 MGI:MGI:5591939 +102635445 Gm32781 MGI:MGI:5591940 +102635447 Ccdc142os MGI:MGI:3783052 +102635448 Gm32783 MGI:MGI:5591942 +102635450 LOC102635450 - +102635451 Gm32784 MGI:MGI:5591943 +102635453 Gm32786 MGI:MGI:5591945 +102635455 Gm32788 MGI:MGI:5591947 +102635456 Gm32789 MGI:MGI:5591948 +102635457 Gm15418 MGI:MGI:3705275 +102635458 Gm32790 MGI:MGI:5591949 +102635459 Gm32791 MGI:MGI:5591950 +102635460 Gm32792 MGI:MGI:5591951 +102635461 Gm32793 MGI:MGI:5591952 +102635462 Gm32794 MGI:MGI:5591953 +102635463 Gm32795 MGI:MGI:5591954 +102635464 Gm32796 MGI:MGI:5591955 +102635466 Gm32797 MGI:MGI:5591956 +102635467 LOC102635467 - +102635468 Gm32798 MGI:MGI:5591957 +102635469 Gm38479 MGI:MGI:5621364 +102635471 Gm32800 MGI:MGI:5591959 +102635472 Gm32801 MGI:MGI:5591960 +102635473 Gm32802 MGI:MGI:5591961 +102635474 Gm32803 MGI:MGI:5591962 +102635476 Gm32805 MGI:MGI:5591964 +102635478 Gm32806 MGI:MGI:5591965 +102635479 Gm32807 MGI:MGI:5591966 +102635480 Gm21894 MGI:MGI:5434058 +102635482 Gm32809 MGI:MGI:5591968 +102635483 Gm29031 MGI:MGI:5579737 +102635484 Gm32810 MGI:MGI:5591969 +102635485 Gm32811 MGI:MGI:5591970 +102635486 Gm32812 MGI:MGI:5591971 +102635487 Gm32813 MGI:MGI:5591972 +102635489 Gm13857 MGI:MGI:3649688 +102635490 Gm26660 MGI:MGI:5477154 +102635491 Gm32815 MGI:MGI:5591974 +102635492 LOC102635492 - +102635493 Gm32816 MGI:MGI:5591975 +102635494 Gm12576 MGI:MGI:3650616 +102635495 Gm32817 MGI:MGI:5591976 +102635496 Malrd1 MGI:MGI:1928271|Ensembl:ENSMUSG00000075520|Vega:OTTMUSG00000051125 +102635497 Gm32818 MGI:MGI:5591977 +102635498 Gm32819 MGI:MGI:5591978 +102635500 Gm32820 MGI:MGI:5591979 +102635502 LOC102635502 - +102635503 Gm32822 MGI:MGI:5591981 +102635504 Gm32823 MGI:MGI:5591982 +102635505 Gm32824 MGI:MGI:5591983 +102635506 Gm32825 MGI:MGI:5591984 +102635507 Gm32826 MGI:MGI:5591985 +102635509 Gm32827 MGI:MGI:5591986 +102635510 Gm12056 MGI:MGI:3652309|Ensembl:ENSMUSG00000085803 +102635511 Scgb2b9-ps MGI:MGI:5578759 +102635512 Gm32828 MGI:MGI:5591987 +102635513 Gm32829 MGI:MGI:5591988 +102635514 LOC102635514 - +102635515 Gm29142 MGI:MGI:5579848 +102635516 Gm32830 MGI:MGI:5591989 +102635519 Gm28326 MGI:MGI:5579032 +102635520 Gm32833 MGI:MGI:5591992 +102635521 LOC102635521 Ensembl:ENSMUSG00000097092 +102635522 Gm32834 MGI:MGI:5591993|Ensembl:ENSMUSG00000112959 +102635523 Gm32835 MGI:MGI:5591994 +102635524 Gm32836 MGI:MGI:5591995 +102635526 Gm32838 MGI:MGI:5591997 +102635527 LOC102635527 - +102635528 Gm32839 MGI:MGI:5591998 +102635529 LOC102635529 - +102635530 Gm32840 MGI:MGI:5591999 +102635531 Gm32841 MGI:MGI:5592000 +102635532 Gm32842 MGI:MGI:5592001 +102635533 Gm32843 MGI:MGI:5592002 +102635534 Gm29154 MGI:MGI:5579860|Ensembl:ENSMUSG00000099722 +102635536 Gm14055 MGI:MGI:3650242 +102635537 Gm32845 MGI:MGI:5592004 +102635538 Gm32846 MGI:MGI:5592005 +102635539 Gm32847 MGI:MGI:5592006 +102635540 Gm32848 MGI:MGI:5592007 +102635541 Gm32849 MGI:MGI:5592008 +102635542 Gm20670 MGI:MGI:5313117 +102635543 Gm32850 MGI:MGI:5592009 +102635544 Gm26698 MGI:MGI:5477192 +102635546 Gm32852 MGI:MGI:5592011 +102635547 Gm28658 MGI:MGI:5579364 +102635549 Gm32853 MGI:MGI:5592012 +102635550 Gm32854 MGI:MGI:5592013 +102635551 Gm32855 MGI:MGI:5592014 +102635552 Gm32856 MGI:MGI:5592015 +102635553 Gm15624 MGI:MGI:3783068 +102635554 LOC102635554 - +102635555 Gm32857 MGI:MGI:5592016 +102635556 Gm32858 MGI:MGI:5592017 +102635557 Gm32859 MGI:MGI:5592018 +102635558 Gm32860 MGI:MGI:5592019 +102635559 Gm32861 MGI:MGI:5592020 +102635560 Gm32862 MGI:MGI:5592021 +102635561 Ggnbp2os MGI:MGI:5508527 +102635562 Gm11571 MGI:MGI:3650087|Ensembl:ENSMUSG00000087581 +102635563 Gm11433 MGI:MGI:3651026 +102635564 Gm32863 MGI:MGI:5592022 +102635565 Gm32864 MGI:MGI:5592023 +102635566 LOC102635566 - +102635567 Gm32865 MGI:MGI:5592024 +102635568 Gm32866 MGI:MGI:5592025 +102635569 Gm27230 MGI:MGI:5521073 +102635570 Gm32867 MGI:MGI:5592026 +102635571 Gm32868 MGI:MGI:5592027 +102635572 Gm38480 MGI:MGI:5621365 +102635573 Gm32869 MGI:MGI:5592028 +102635574 Gm17196 MGI:MGI:4938023 +102635575 Gm11264 MGI:MGI:3649480|Ensembl:ENSMUSG00000087110 +102635576 Gm32870 MGI:MGI:5592029 +102635577 Gm32871 MGI:MGI:5592030 +102635578 Gm32872 MGI:MGI:5592031 +102635580 Gm32874 MGI:MGI:5592033 +102635581 Gm32875 MGI:MGI:5592034 +102635582 Gm32876 MGI:MGI:5592035 +102635583 Gm32877 MGI:MGI:5592036 +102635584 Gm32878 MGI:MGI:5592037 +102635585 Gm32879 MGI:MGI:5592038 +102635586 Gm26725 MGI:MGI:5477219 +102635587 Gm32880 MGI:MGI:5592039 +102635588 Gm32881 MGI:MGI:5592040 +102635589 Gm11020 MGI:MGI:3779240 +102635590 Gm32882 MGI:MGI:5592041 +102635592 Gm32884 MGI:MGI:5592043 +102635593 Gm28836 MGI:MGI:5579542 +102635594 Gm32885 MGI:MGI:5592044 +102635595 Gm32886 MGI:MGI:5592045 +102635596 Gm32887 MGI:MGI:5592046 +102635597 Gm32888 MGI:MGI:5592047 +102635600 Gm32891 MGI:MGI:5592050 +102635601 Gm32892 MGI:MGI:5592051 +102635602 Gm32893 MGI:MGI:5592052 +102635603 Gm32894 MGI:MGI:5592053 +102635605 Gm32896 MGI:MGI:5592055 +102635606 Gm32897 MGI:MGI:5592056 +102635607 Gm32898 MGI:MGI:5592057 +102635608 Scgb2b29-ps MGI:MGI:5578753 +102635609 Gm32899 MGI:MGI:5592058 +102635610 Gm32900 MGI:MGI:5592059 +102635612 Gm32902 MGI:MGI:5592061 +102635613 Gm32903 MGI:MGI:5592062 +102635614 Gm32904 MGI:MGI:5592063 +102635616 Gm32906 MGI:MGI:5592065 +102635617 Gm21756 MGI:MGI:5433920 +102635619 Gm32908 MGI:MGI:5592067 +102635621 Gm32910 MGI:MGI:5592069 +102635622 Gm26664 MGI:MGI:5477158 +102635623 Gm32911 MGI:MGI:5592070 +102635624 Gm32912 MGI:MGI:5592071 +102635625 Gm32913 MGI:MGI:5592072 +102635626 Gm32914 MGI:MGI:5592073 +102635627 Gm32915 MGI:MGI:5592074 +102635628 Gm32916 MGI:MGI:5592075 +102635629 Gm32917 MGI:MGI:5592076 +102635630 Gm32918 MGI:MGI:5592077 +102635632 Gm32920 MGI:MGI:5592079 +102635633 Gm32921 MGI:MGI:5592080|Ensembl:ENSMUSG00000105508 +102635635 Gm32923 MGI:MGI:5592082 +102635636 Gm32924 MGI:MGI:5592083 +102635637 Gm32925 MGI:MGI:5592084 +102635638 LOC102635638 - +102635639 Gm32926 MGI:MGI:5592085|Ensembl:ENSMUSG00000111474 +102635640 Gm32927 MGI:MGI:5592086 +102635641 Gm32928 MGI:MGI:5592087 +102635642 Gm32929 MGI:MGI:5592088 +102635643 Gm32930 MGI:MGI:5592089 +102635644 Gm32931 MGI:MGI:5592090 +102635646 Gm32932 MGI:MGI:5592091 +102635648 Gm32934 MGI:MGI:5592093 +102635649 Gm32935 MGI:MGI:5592094 +102635650 Gm32936 MGI:MGI:5592095 +102635653 Gm29573 MGI:MGI:5580279 +102635654 Gm32939 MGI:MGI:5592098 +102635655 Gm28375 MGI:MGI:5579081 +102635656 Gm32940 MGI:MGI:5592099 +102635657 Gm32941 MGI:MGI:5592100 +102635658 LOC102635658 - +102635659 LOC102635659 - +102635660 LOC102635660 - +102635661 LOC102635661 - +102635662 Gm32942 MGI:MGI:5592101 +102635663 Gm32943 MGI:MGI:5592102 +102635665 Gm32945 MGI:MGI:5592104 +102635666 Gm32946 MGI:MGI:5592105 +102635667 Gm32947 MGI:MGI:5592106 +102635670 Gm32949 MGI:MGI:5592108 +102635671 Gm32950 MGI:MGI:5592109 +102635672 Gm32951 MGI:MGI:5592110 +102635673 Gm26569 MGI:MGI:5477063 +102635674 Gm13322 MGI:MGI:3650424 +102635675 Gm32952 MGI:MGI:5592111 +102635677 Gm32954 MGI:MGI:5592113 +102635678 Gm32955 MGI:MGI:5592114 +102635680 Gm32957 MGI:MGI:5592116 +102635681 Gm14064 MGI:MGI:3649737 +102635682 LOC102635682 - +102635683 Gm32958 MGI:MGI:5592117 +102635684 Gm32959 MGI:MGI:5592118 +102635685 Gm32960 MGI:MGI:5592119 +102635687 Gm32962 MGI:MGI:5592121 +102635688 Gm32963 MGI:MGI:5592122 +102635689 Gm28212 MGI:MGI:5578918 +102635690 Gm11281 MGI:MGI:3651906 +102635691 Gm28608 MGI:MGI:5579314 +102635692 Gm32964 MGI:MGI:5592123 +102635693 Gm32965 MGI:MGI:5592124 +102635694 Gm32966 MGI:MGI:5592125 +102635695 Gm32967 MGI:MGI:5592126 +102635696 Gm32968 MGI:MGI:5592127 +102635697 Gm32969 MGI:MGI:5592128 +102635698 Gm26679 MGI:MGI:5477173 +102635699 Gm32970 MGI:MGI:5592129 +102635700 Gm32971 MGI:MGI:5592130 +102635701 Gm32972 MGI:MGI:5592131 +102635702 Gm32973 MGI:MGI:5592132 +102635703 Gm32974 MGI:MGI:5592133 +102635704 Gm32975 MGI:MGI:5592134 +102635705 LOC102635705 - +102635706 Gm32976 MGI:MGI:5592135 +102635707 LOC102635707 Ensembl:ENSMUSG00000100303 +102635709 Gm14319 MGI:MGI:3649450 +102635711 Gm32979 MGI:MGI:5592138 +102635712 Gm32980 MGI:MGI:5592139 +102635714 LOC102635714 - +102635715 Gm32981 MGI:MGI:5592140 +102635717 Gm32983 MGI:MGI:5592142 +102635718 Gm28211 MGI:MGI:5578917 +102635720 LOC102635720 - +102635721 Gm26651 MGI:MGI:5477145 +102635722 Gm32985 MGI:MGI:5592144 +102635723 Gm32986 MGI:MGI:5592145 +102635725 Gm32988 MGI:MGI:5592147 +102635727 Gm32990 MGI:MGI:5592149 +102635729 Gm32992 MGI:MGI:5592151 +102635731 Gm32994 MGI:MGI:5592153 +102635732 LOC102635732 - +102635733 Gm32995 MGI:MGI:5592154 +102635734 Gm32996 MGI:MGI:5592155 +102635735 Gm32997 MGI:MGI:5592156 +102635736 Gm32998 MGI:MGI:5592157 +102635737 Gm32999 MGI:MGI:5592158 +102635738 Gm33000 MGI:MGI:5592159 +102635741 Gm33002 MGI:MGI:5592161 +102635742 Gm33003 MGI:MGI:5592162 +102635743 Gm33004 MGI:MGI:5592163 +102635744 Gm28729 MGI:MGI:5579435|Ensembl:ENSMUSG00000099564|Vega:OTTMUSG00000046498 +102635746 Gm33006 MGI:MGI:5592165 +102635747 Gm33007 MGI:MGI:5592166 +102635748 Gm33008 MGI:MGI:5592167 +102635749 Gm33009 MGI:MGI:5592168 +102635750 Gm33010 MGI:MGI:5592169 +102635751 Gm14216 MGI:MGI:3650218 +102635752 Gm33011 MGI:MGI:5592170 +102635755 Gm33013 MGI:MGI:5592172 +102635756 Gm15689 MGI:MGI:3783130 +102635757 Gm33014 MGI:MGI:5592173 +102635758 Gm33015 MGI:MGI:5592174 +102635759 Gm33016 MGI:MGI:5592175|Ensembl:ENSMUSG00000113278 +102635760 LOC102635760 - +102635761 Gm28606 MGI:MGI:5579312|Ensembl:ENSMUSG00000100544 +102635762 Gm28377 MGI:MGI:5579083 +102635763 Gm33017 MGI:MGI:5592176 +102635764 Gm33018 MGI:MGI:5592177 +102635765 Gm33019 MGI:MGI:5592178 +102635766 Gm33020 MGI:MGI:5592179 +102635768 Gm33022 MGI:MGI:5592181 +102635769 Gm33023 MGI:MGI:5592182|Ensembl:ENSMUSG00000110652 +102635770 Gm26739 MGI:MGI:5477233 +102635771 Gm33024 MGI:MGI:5592183 +102635772 Gm26748 MGI:MGI:5477242 +102635773 Gm33025 MGI:MGI:5592184 +102635774 Gm33026 MGI:MGI:5592185 +102635775 Gm33027 MGI:MGI:5592186 +102635776 Gm33028 MGI:MGI:5592187 +102635777 Gm11506 MGI:MGI:3650724 +102635778 Gm33029 MGI:MGI:5592188 +102635779 Gm33030 MGI:MGI:5592189 +102635780 Gm33031 MGI:MGI:5592190 +102635781 Gm38481 MGI:MGI:5621366 +102635782 Gm33032 MGI:MGI:5592191 +102635783 Gm11266 MGI:MGI:3649705 +102635784 Gm33033 MGI:MGI:5592192 +102635785 Gm33034 MGI:MGI:5592193 +102635786 LOC102635786 - +102635787 Gm33035 MGI:MGI:5592194 +102635788 Gm33036 MGI:MGI:5592195 +102635789 Gm33037 MGI:MGI:5592196 +102635791 Gm33039 MGI:MGI:5592198 +102635792 Gm33040 MGI:MGI:5592199 +102635793 Gm33041 MGI:MGI:5592200 +102635794 Gm33042 MGI:MGI:5592201 +102635795 Gm33043 MGI:MGI:5592202 +102635796 Gm33044 MGI:MGI:5592203 +102635797 Gm33045 MGI:MGI:5592204|Ensembl:ENSMUSG00000109853 +102635798 Gm33046 MGI:MGI:5592205 +102635799 Gm33047 MGI:MGI:5592206 +102635800 Gm33048 MGI:MGI:5592207 +102635801 LOC102635801 - +102635802 Gm33049 MGI:MGI:5592208 +102635803 Gm33050 MGI:MGI:5592209 +102635804 Gm33051 MGI:MGI:5592210 +102635805 Gm33052 MGI:MGI:5592211 +102635807 Gm33053 MGI:MGI:5592212 +102635808 Gm33054 MGI:MGI:5592213 +102635809 Gm33055 MGI:MGI:5592214 +102635810 Gm33056 MGI:MGI:5592215 +102635811 Gm33057 MGI:MGI:5592216 +102635812 Gm33058 MGI:MGI:5592217 +102635813 Gm33059 MGI:MGI:5592218 +102635814 Gm33060 MGI:MGI:5592219 +102635815 Gm33061 MGI:MGI:5592220 +102635817 Gm33062 MGI:MGI:5592221 +102635820 Gm33065 MGI:MGI:5592224 +102635821 Gm33066 MGI:MGI:5592225 +102635822 Gm33067 MGI:MGI:5592226 +102635823 Gm33068 MGI:MGI:5592227 +102635824 Gm33069 MGI:MGI:5592228 +102635825 Gm28093 MGI:MGI:5578799 +102635826 Gm16086 MGI:MGI:3801936 +102635827 Gm33070 MGI:MGI:5592229 +102635830 Gm29371 MGI:MGI:5580077 +102635831 Gm33073 MGI:MGI:5592232 +102635832 Gm33074 MGI:MGI:5592233 +102635833 LOC102635833 - +102635834 Gm33075 MGI:MGI:5592234 +102635835 Gm33076 MGI:MGI:5592235 +102635836 Gm33077 MGI:MGI:5592236 +102635837 Gm33078 MGI:MGI:5592237 +102635839 Gm33080 MGI:MGI:5592239 +102635841 Gm33082 MGI:MGI:5592241 +102635843 Gm33083 MGI:MGI:5592242 +102635844 LOC102635844 - +102635845 Gm33084 MGI:MGI:5592243 +102635846 Gm33085 MGI:MGI:5592244 +102635847 Gm33086 MGI:MGI:5592245 +102635849 Gm13427 MGI:MGI:3650808 +102635850 Gm27254 MGI:MGI:5521097 +102635851 Gm33088 MGI:MGI:5592247 +102635852 Gm33089 MGI:MGI:5592248 +102635853 Gm16283 MGI:MGI:3826591 +102635854 Gm33090 MGI:MGI:5592249 +102635855 Gm33091 MGI:MGI:5592250 +102635856 Gm33092 MGI:MGI:5592251 +102635858 Gm29165 MGI:MGI:5579871 +102635859 Gm33093 MGI:MGI:5592252 +102635860 Gm21724 MGI:MGI:5433888 +102635861 Gm29179 MGI:MGI:5579885 +102635862 Gm33094 MGI:MGI:5592253 +102635863 LOC102635863 - +102635864 Gm29312 MGI:MGI:5580018 +102635866 Gm33096 MGI:MGI:5592255 +102635867 Gm33097 MGI:MGI:5592256 +102635868 Gm26728 MGI:MGI:5477222 +102635869 Gm33098 MGI:MGI:5592257 +102635870 Gm12315 MGI:MGI:3652244 +102635873 Gm33099 MGI:MGI:5592258 +102635874 Gm33100 MGI:MGI:5592259|Ensembl:ENSMUSG00000106319 +102635875 Gm33101 MGI:MGI:5592260 +102635876 Gm33102 MGI:MGI:5592261 +102635877 Gm33103 MGI:MGI:5592262 +102635878 Gm14033 MGI:MGI:3650902 +102635879 LOC102635879 - +102635880 Gm33104 MGI:MGI:5592263|Ensembl:ENSMUSG00000110902 +102635881 Gm33105 MGI:MGI:5592264 +102635882 Gm33106 MGI:MGI:5592265 +102635884 Gm33108 MGI:MGI:5592267 +102635886 Gm33109 MGI:MGI:5592268 +102635888 Gm33111 MGI:MGI:5592270|Ensembl:ENSMUSG00000112569 +102635889 Gm33112 MGI:MGI:5592271 +102635891 Gm28518 MGI:MGI:5579224|Ensembl:ENSMUSG00000100790 +102635892 Gm12807 MGI:MGI:3650599 +102635893 LOC102635893 - +102635894 Gm33114 MGI:MGI:5592273 +102635895 Gm33115 MGI:MGI:5592274|Ensembl:ENSMUSG00000114192 +102635896 Gm33116 MGI:MGI:5592275 +102635898 Gm33118 MGI:MGI:5592277 +102635899 Gm33119 MGI:MGI:5592278 +102635900 Gm33120 MGI:MGI:5592279 +102635901 Gm10444 MGI:MGI:3642569 +102635902 Gm33121 MGI:MGI:5592280 +102635903 LOC102635903 - +102635904 Gm33122 MGI:MGI:5592281 +102635905 Gm33123 MGI:MGI:5592282 +102635906 Gm33124 MGI:MGI:5592283 +102635907 Gm28900 MGI:MGI:5579606 +102635908 Gm33125 MGI:MGI:5592284 +102635909 Gm33126 MGI:MGI:5592285 +102635911 Platr11 MGI:MGI:5504090 +102635912 LOC102635912 - +102635913 Gm33128 MGI:MGI:5592287 +102635915 Gm33130 MGI:MGI:5592289 +102635920 Gm33134 MGI:MGI:5592293 +102635921 Gm33135 MGI:MGI:5592294 +102635922 Gm33136 MGI:MGI:5592295 +102635925 Gm29189 MGI:MGI:5579895 +102635926 Gm33139 MGI:MGI:5592298 +102635927 Gm33140 MGI:MGI:5592299 +102635928 Gm26715 MGI:MGI:5477209 +102635929 Gm33141 MGI:MGI:5592300 +102635930 Gm33142 MGI:MGI:5592301 +102635932 Gm33143 MGI:MGI:5592302 +102635933 Gm33144 MGI:MGI:5592303 +102635934 Gm33145 MGI:MGI:5592304 +102635935 Gm12320 MGI:MGI:3649512 +102635936 Gm33146 MGI:MGI:5592305 +102635937 Gm12348 MGI:MGI:3652160 +102635938 Gm33147 MGI:MGI:5592306 +102635939 Gm33148 MGI:MGI:5592307 +102635940 Gm33149 MGI:MGI:5592308 +102635942 Gm33151 MGI:MGI:5592310 +102635943 Gm33152 MGI:MGI:5592311 +102635944 Gm33153 MGI:MGI:5592312 +102635945 Gm33154 MGI:MGI:5592313 +102635946 Gm33155 MGI:MGI:5592314|Ensembl:ENSMUSG00000087526 +102635948 LOC102635948 Ensembl:ENSMUSG00000086742 +102635949 Gm33157 MGI:MGI:5592316 +102635950 Gm33158 MGI:MGI:5592317 +102635951 Gm27204 MGI:MGI:5521047 +102635952 Gm33159 MGI:MGI:5592318 +102635953 Gm33160 MGI:MGI:5592319 +102635954 Gm14089 MGI:MGI:3650468 +102635955 Gm14062 MGI:MGI:3649735 +102635956 Gm33161 MGI:MGI:5592320 +102635957 Gm33162 MGI:MGI:5592321 +102635958 Gm20389 MGI:MGI:5141854|Ensembl:ENSMUSG00000092522 +102635959 Gm33163 MGI:MGI:5592322 +102635960 LOC102635960 - +102635961 Gm28504 MGI:MGI:5579210 +102635964 Gm28699 MGI:MGI:5579405 +102635965 Gm33166 MGI:MGI:5592325 +102635966 Gm33167 MGI:MGI:5592326 +102635967 Gm33168 MGI:MGI:5592327 +102635968 Gm33169 MGI:MGI:5592328 +102635970 Gm33171 MGI:MGI:5592330 +102635971 Gm33172 MGI:MGI:5592331 +102635972 Gm33173 MGI:MGI:5592332 +102635973 Akirin1-ps MGI:MGI:3650065 +102635974 Gm11625 MGI:MGI:3650862 +102635975 Gm33174 MGI:MGI:5592333 +102635976 Gm33175 MGI:MGI:5592334 +102635977 Gm33176 MGI:MGI:5592335 +102635979 Gm33178 MGI:MGI:5592337 +102635981 Gm33180 MGI:MGI:5592339|Ensembl:ENSMUSG00000111852 +102635983 Gm33182 MGI:MGI:5592341 +102635985 Gm11269 MGI:MGI:3649855 +102635987 Gm33185 MGI:MGI:5592344 +102635989 Gm33187 MGI:MGI:5592346 +102635990 LOC102635990 Ensembl:ENSMUSG00000044581 +102635991 Gm33188 MGI:MGI:5592347 +102635992 LOC102635992 Ensembl:ENSMUSG00000099581|Vega:OTTMUSG00000045746 +102635993 Gm33189 MGI:MGI:5592348 +102635994 Gm33190 MGI:MGI:5592349 +102635995 Gm33191 MGI:MGI:5592350 +102635996 Gm33192 MGI:MGI:5592351 +102635997 LOC102635997 - +102636000 Gm33195 MGI:MGI:5592354 +102636002 Gm33197 MGI:MGI:5592356 +102636003 Gm33198 MGI:MGI:5592357 +102636004 Gm33199 MGI:MGI:5592358 +102636005 Gm33200 MGI:MGI:5592359 +102636006 Gm33201 MGI:MGI:5592360 +102636007 Gm33202 MGI:MGI:5592361 +102636008 Gm33203 MGI:MGI:5592362 +102636009 Gm33204 MGI:MGI:5592363 +102636010 Gm15603 MGI:MGI:3783050 +102636011 Gm38482 MGI:MGI:5621367 +102636012 Gm33205 MGI:MGI:5592364 +102636013 Gm28050 MGI:MGI:5547786 +102636014 Gm33206 MGI:MGI:5592365 +102636015 Gm33207 MGI:MGI:5592366 +102636017 Gm33208 MGI:MGI:5592367 +102636018 Gm33209 MGI:MGI:5592368 +102636019 Gm33210 MGI:MGI:5592369 +102636020 Gm33211 MGI:MGI:5592370 +102636022 Gm13572 MGI:MGI:3652224|Ensembl:ENSMUSG00000085975 +102636024 LOC102636024 - +102636025 Gm33214 MGI:MGI:5592373 +102636026 LOC102636026 - +102636027 Gm33215 MGI:MGI:5592374 +102636028 LOC102636028 - +102636029 Gm29293 MGI:MGI:5579999 +102636030 Gm29467 MGI:MGI:5580173 +102636033 Gm33217 MGI:MGI:5592376 +102636034 Gm33218 MGI:MGI:5592377 +102636035 Gm33219 MGI:MGI:5592378 +102636036 Gm33220 MGI:MGI:5592379 +102636037 Gm38483 MGI:MGI:5621368 +102636038 Gm33221 MGI:MGI:5592380 +102636039 Gm33222 MGI:MGI:5592381 +102636040 Gm33223 MGI:MGI:5592382 +102636041 Gm38484 MGI:MGI:5621369|Ensembl:ENSMUSG00000087022 +102636042 Gm33224 MGI:MGI:5592383 +102636044 Gm33226 MGI:MGI:5592385 +102636045 Gm16185 MGI:MGI:3802169 +102636046 Gm28548 MGI:MGI:5579254|Ensembl:ENSMUSG00000099599 +102636048 Gm38485 MGI:MGI:5621370 +102636049 Gm33228 MGI:MGI:5592387 +102636050 Gm33229 MGI:MGI:5592388 +102636051 Gm13097 MGI:MGI:3701129 +102636052 Gm33230 MGI:MGI:5592389 +102636054 Gm33232 MGI:MGI:5592391 +102636055 Gm38486 MGI:MGI:5621371 +102636056 Gm33233 MGI:MGI:5592392 +102636057 Gm33234 MGI:MGI:5592393 +102636058 Gm33235 MGI:MGI:5592394 +102636059 Gm33236 MGI:MGI:5592395 +102636060 LOC102636060 - +102636061 Gm33237 MGI:MGI:5592396 +102636063 Gm21873 MGI:MGI:5434037 +102636064 Gm28542 MGI:MGI:5579248 +102636066 Gm33239 MGI:MGI:5592398 +102636067 Gm33240 MGI:MGI:5592399 +102636069 Gm33242 MGI:MGI:5592401 +102636070 Gm33243 MGI:MGI:5592402 +102636071 Gm33244 MGI:MGI:5592403 +102636074 Gm33246 MGI:MGI:5592405 +102636075 Gm33247 MGI:MGI:5592406 +102636076 Gm33248 MGI:MGI:5592407 +102636077 Gm33249 MGI:MGI:5592408 +102636078 Gm33250 MGI:MGI:5592409 +102636079 Gm33251 MGI:MGI:5592410 +102636081 Gm33253 MGI:MGI:5592412 +102636082 Ccdc168 - +102636083 Mannr MGI:MGI:5564803|Ensembl:ENSMUSG00000102590 +102636084 Gm33254 MGI:MGI:5592413 +102636085 Gm33255 MGI:MGI:5592414 +102636086 Gm33256 MGI:MGI:5592415 +102636087 Gm13609 MGI:MGI:3651299 +102636088 Gm33257 MGI:MGI:5592416 +102636089 Gm33258 MGI:MGI:5592417 +102636090 Gm33259 MGI:MGI:5592418 +102636091 Tmc4-ps MGI:MGI:3651628 +102636092 Gm33260 MGI:MGI:5592419 +102636093 Gm13571 MGI:MGI:3652223 +102636094 Gm33261 MGI:MGI:5592420 +102636095 Gm33262 MGI:MGI:5592421 +102636096 Gm33263 MGI:MGI:5592422|Ensembl:ENSMUSG00000111941 +102636097 Gm33264 MGI:MGI:5592423 +102636098 Gm33265 MGI:MGI:5592424 +102636099 Gm33266 MGI:MGI:5592425 +102636100 Gm27321 MGI:MGI:5530703 +102636101 LOC102636101 - +102636102 Gm33267 MGI:MGI:5592426 +102636104 Gm33269 MGI:MGI:5592428 +102636107 Gm33272 MGI:MGI:5592431 +102636108 Gm29383 MGI:MGI:5580089 +102636109 Gm33273 MGI:MGI:5592432 +102636110 LOC102636110 - +102636111 Gm33274 MGI:MGI:5592433 +102636112 Gm33275 MGI:MGI:5592434 +102636113 Gm15572 MGI:MGI:3783020 +102636114 Gm33276 MGI:MGI:5592435 +102636115 Gm33277 MGI:MGI:5592436 +102636117 Gm33279 MGI:MGI:5592438 +102636118 Gm33280 MGI:MGI:5592439 +102636119 Gm33281 MGI:MGI:5592440 +102636121 Gm33283 MGI:MGI:5592442 +102636123 Gm33284 MGI:MGI:5592443 +102636124 LOC102636124 - +102636126 Gm27211 MGI:MGI:5521054|Ensembl:ENSMUSG00000098875 +102636127 Gm33285 MGI:MGI:5592444 +102636128 Gm33286 MGI:MGI:5592445 +102636129 LOC102636129 - +102636130 Gm14061 MGI:MGI:3649736 +102636131 Gm13067 MGI:MGI:3651968 +102636132 Gm33287 MGI:MGI:5592446 +102636133 Gm12066 MGI:MGI:3649818 +102636134 Gm33288 MGI:MGI:5592447 +102636135 Gm33289 MGI:MGI:5592448 +102636136 Gm33290 MGI:MGI:5592449 +102636137 Gm33291 MGI:MGI:5592450 +102636138 Gm33292 MGI:MGI:5592451 +102636139 Gm33293 MGI:MGI:5592452 +102636140 Gm28867 MGI:MGI:5579573 +102636141 Gm33294 MGI:MGI:5592453 +102636142 4930526H09Rik MGI:MGI:1922389 +102636144 Gm33296 MGI:MGI:5592455 +102636145 Gm33297 MGI:MGI:5592456 +102636146 Gm27177 MGI:MGI:5521020 +102636147 Gm33298 MGI:MGI:5592457 +102636148 Gm33299 MGI:MGI:5592458 +102636149 Gm16013 MGI:MGI:3801787 +102636150 Gm33300 MGI:MGI:5592459 +102636151 Gm33301 MGI:MGI:5592460 +102636152 Gm28068 MGI:MGI:5578774 +102636154 Gm16124 MGI:MGI:3802001|Ensembl:ENSMUSG00000086914 +102636155 Gm33302 MGI:MGI:5592461 +102636156 LOC102636156 - +102636158 LOC102636158 - +102636159 Gm33304 MGI:MGI:5592463 +102636160 LOC102636160 - +102636161 Gm33305 MGI:MGI:5592464 +102636162 Gm33306 MGI:MGI:5592465 +102636164 Gm14502 MGI:MGI:3705819 +102636165 Gm33308 MGI:MGI:5592467|Ensembl:ENSMUSG00000112578 +102636166 Gm33309 MGI:MGI:5592468 +102636167 Gm33310 MGI:MGI:5592469 +102636168 Gm33311 MGI:MGI:5592470 +102636169 Gm33312 MGI:MGI:5592471 +102636171 Gm28253 MGI:MGI:5578959 +102636173 Gm21880 MGI:MGI:5434044 +102636174 Gm21823 MGI:MGI:5433987 +102636175 Gm33315 MGI:MGI:5592474 +102636177 Gm33317 MGI:MGI:5592476 +102636178 Gm33318 MGI:MGI:5592477 +102636179 Gm33319 MGI:MGI:5592478 +102636180 Gm33320 MGI:MGI:5592479 +102636181 Gm33321 MGI:MGI:5592480 +102636183 LOC102636183 - +102636184 Gm33323 MGI:MGI:5592482 +102636186 Dhx58os MGI:MGI:3705104 +102636187 Gm33324 MGI:MGI:5592483 +102636188 Gm33325 MGI:MGI:5592484 +102636189 Gm33326 MGI:MGI:5592485 +102636191 Gm15759 MGI:MGI:3783202 +102636192 Gm33327 MGI:MGI:5592486 +102636193 Gm33328 MGI:MGI:5592487 +102636194 Gm33329 MGI:MGI:5592488 +102636195 Gm33330 MGI:MGI:5592489 +102636197 Gm33332 MGI:MGI:5592491 +102636198 Gm33333 MGI:MGI:5592492 +102636199 Gm33334 MGI:MGI:5592493 +102636200 Gm33335 MGI:MGI:5592494 +102636201 Gm33336 MGI:MGI:5592495 +102636202 Gm33337 MGI:MGI:5592496 +102636203 LOC102636203 - +102636205 Gm33339 MGI:MGI:5592498 +102636206 Gm28951 MGI:MGI:5579657 +102636207 Gm33340 MGI:MGI:5592499 +102636208 Gm33341 MGI:MGI:5592500 +102636211 Gm28179 MGI:MGI:5578885 +102636213 Gm33345 MGI:MGI:5592504 +102636214 Gm33346 MGI:MGI:5592505 +102636215 Gm33347 MGI:MGI:5592506 +102636216 Gm29257 MGI:MGI:5579963 +102636217 Gm26806 MGI:MGI:5477300 +102636218 Gm15290 MGI:MGI:3705144 +102636219 Gm33348 MGI:MGI:5592507 +102636220 Gm33349 MGI:MGI:5592508 +102636221 Gm33350 MGI:MGI:5592509 +102636222 Gm33351 MGI:MGI:5592510 +102636223 Gm33352 MGI:MGI:5592511 +102636224 Gm33353 MGI:MGI:5592512 +102636225 Gm28410 MGI:MGI:5579116 +102636226 Gm33354 MGI:MGI:5592513 +102636227 Gm33355 MGI:MGI:5592514 +102636229 Gm33357 MGI:MGI:5592516 +102636230 Gm33358 MGI:MGI:5592517 +102636231 LOC102636231 - +102636232 Gm11184 MGI:MGI:3651087 +102636233 LOC102636233 - +102636236 Gm33359 MGI:MGI:5592518 +102636238 Gm33361 MGI:MGI:5592520 +102636239 Gm27042 MGI:MGI:5504157 +102636241 Gm33363 MGI:MGI:5592522 +102636242 Gm28245 MGI:MGI:5578951 +102636244 Gm21912 MGI:MGI:5434076 +102636245 Gm29190 MGI:MGI:5579896 +102636246 Gm33365 MGI:MGI:5592524 +102636247 Gm33366 MGI:MGI:5592525 +102636248 Gm33367 MGI:MGI:5592526 +102636249 Gm33368 MGI:MGI:5592527 +102636250 Gm33369 MGI:MGI:5592528 +102636251 Gm33370 MGI:MGI:5592529 +102636252 Gm33371 MGI:MGI:5592530 +102636253 Gm33372 MGI:MGI:5592531 +102636254 LOC102636254 - +102636255 LOC102636255 - +102636256 Gm33373 MGI:MGI:5592532 +102636257 Gm33374 MGI:MGI:5592533 +102636258 Gm11802 MGI:MGI:3650651 +102636259 Gm33375 MGI:MGI:5592534 +102636260 Gm33376 MGI:MGI:5592535 +102636262 Gm20544 MGI:MGI:5142009 +102636263 Gm33377 MGI:MGI:5592536 +102636264 Gm33378 MGI:MGI:5592537 +102636265 Gm33379 MGI:MGI:5592538 +102636266 Gm33380 MGI:MGI:5592539 +102636267 Gm33381 MGI:MGI:5592540 +102636268 Gm33382 MGI:MGI:5592541 +102636269 Gm33383 MGI:MGI:5592542 +102636270 Gm33384 MGI:MGI:5592543 +102636271 Gm33385 MGI:MGI:5592544 +102636273 Gm28819 MGI:MGI:5579525 +102636274 Gm33387 MGI:MGI:5592546 +102636275 Gm26756 MGI:MGI:5477250 +102636276 Gm33388 MGI:MGI:5592547 +102636277 Gm33389 MGI:MGI:5592548 +102636278 Gm33390 MGI:MGI:5592549 +102636279 Gm33391 MGI:MGI:5592550 +102636280 Gm33392 MGI:MGI:5592551 +102636282 Gm17124 MGI:MGI:4937951 +102636283 Gm17093 MGI:MGI:4937920 +102636284 LOC102636284 - +102636286 Gm33394 MGI:MGI:5592553 +102636287 Gm33395 MGI:MGI:5592554 +102636289 Gm33397 MGI:MGI:5592556 +102636290 Gm33398 MGI:MGI:5592557 +102636293 Gm33401 MGI:MGI:5592560 +102636294 Gm33402 MGI:MGI:5592561 +102636296 Gm33403 MGI:MGI:5592562 +102636297 Gm33404 MGI:MGI:5592563 +102636299 LOC102636299 - +102636301 Gm33406 MGI:MGI:5592565 +102636302 Gm33407 MGI:MGI:5592566 +102636303 Gm33408 MGI:MGI:5592567 +102636304 Gm33409 MGI:MGI:5592568 +102636305 Gm33410 MGI:MGI:5592569 +102636306 Gm33411 MGI:MGI:5592570 +102636307 Gm33412 MGI:MGI:5592571 +102636309 LOC102636309 - +102636310 Gm33413 MGI:MGI:5592572 +102636312 Gm33415 MGI:MGI:5592574 +102636313 LOC102636313 - +102636314 Gm33416 MGI:MGI:5592575 +102636315 Gm33417 MGI:MGI:5592576 +102636316 Gm33418 MGI:MGI:5592577 +102636319 Gm28247 MGI:MGI:5578953 +102636320 Gm33420 MGI:MGI:5592579 +102636324 Gm33424 MGI:MGI:5592583 +102636327 Gm33426 MGI:MGI:5592585 +102636328 Gm33427 MGI:MGI:5592586 +102636329 Gm33428 MGI:MGI:5592587 +102636330 Gm26878 MGI:MGI:5477372 +102636331 Gm33429 MGI:MGI:5592588 +102636332 Gm33430 MGI:MGI:5592589 +102636333 Gm33431 MGI:MGI:5592590 +102636334 Gm33432 MGI:MGI:5592591 +102636335 Gm33433 MGI:MGI:5592592 +102636338 LOC102636338 - +102636339 Gm16005 MGI:MGI:3801854 +102636341 Gm33434 MGI:MGI:5592593 +102636342 Gm33435 MGI:MGI:5592594 +102636343 Gm33436 MGI:MGI:5592595 +102636344 Gm33437 MGI:MGI:5592596 +102636345 Gm33438 MGI:MGI:5592597 +102636346 Gm33439 MGI:MGI:5592598 +102636347 Gm33440 MGI:MGI:5592599 +102636348 Gm33441 MGI:MGI:5592600 +102636349 LOC102636349 Ensembl:ENSMUSG00000086207 +102636350 Gm33442 MGI:MGI:5592601 +102636351 Astx4b MGI:MGI:3705312 +102636354 Gm33444 MGI:MGI:5592603 +102636355 LOC102636355 - +102636357 LOC102636357 - +102636358 Gm33446 MGI:MGI:5592605 +102636359 Gm33447 MGI:MGI:5592606 +102636360 LOC102636360 - +102636361 Gm33448 MGI:MGI:5592607 +102636362 Gm33449 MGI:MGI:5592608 +102636363 Gm33450 MGI:MGI:5592609 +102636365 Gm33452 MGI:MGI:5592611 +102636366 Gm33453 MGI:MGI:5592612 +102636367 LOC102636367 - +102636368 Gm33454 MGI:MGI:5592613 +102636369 Gm33455 MGI:MGI:5592614 +102636371 Gm33456 MGI:MGI:5592615 +102636372 Gm33457 MGI:MGI:5592616 +102636373 Gm33458 MGI:MGI:5592617 +102636374 Gm33459 MGI:MGI:5592618 +102636375 Gm33460 MGI:MGI:5592619 +102636376 Gm33461 MGI:MGI:5592620 +102636377 Gm33462 MGI:MGI:5592621 +102636378 Macrod2os1 MGI:MGI:3650192 +102636379 LOC102636379 - +102636380 LOC102636380 - +102636381 Gm33463 MGI:MGI:5592622 +102636382 Gm33464 MGI:MGI:5592623 +102636385 Gm16160 MGI:MGI:3802143 +102636386 Gm33466 MGI:MGI:5592625 +102636387 Gm33467 MGI:MGI:5592626 +102636388 Gm33468 MGI:MGI:5592627 +102636389 Gm28462 MGI:MGI:5579168 +102636390 Gm28739 MGI:MGI:5579445 +102636391 Gm33469 MGI:MGI:5592628 +102636392 Gm33470 MGI:MGI:5592629 +102636393 LOC102636393 - +102636394 Gm26925 MGI:MGI:5504040 +102636395 Gm33471 MGI:MGI:5592630 +102636396 Gm33472 MGI:MGI:5592631 +102636397 Gm33473 MGI:MGI:5592632 +102636398 LOC102636398 - +102636399 Gm33474 MGI:MGI:5592633 +102636400 Gm33475 MGI:MGI:5592634 +102636401 Gm33476 MGI:MGI:5592635 +102636404 Gm33479 MGI:MGI:5592638 +102636405 Gm33480 MGI:MGI:5592639 +102636406 LOC102636406 Ensembl:ENSMUSG00000087069 +102636407 Gm33481 MGI:MGI:5592640 +102636408 Gm33482 MGI:MGI:5592641 +102636409 Gm33483 MGI:MGI:5592642 +102636410 Gm33484 MGI:MGI:5592643 +102636411 Gm33485 MGI:MGI:5592644 +102636412 Gm33486 MGI:MGI:5592645 +102636413 Gm21820 MGI:MGI:5433984 +102636414 Gm38487 MGI:MGI:5621372 +102636415 Gm33487 MGI:MGI:5592646 +102636416 Gm28090 MGI:MGI:5578796 +102636417 LOC102636417 - +102636418 Gm21739 MGI:MGI:5433903 +102636419 Gm28553 MGI:MGI:5579259 +102636420 Gm33488 MGI:MGI:5592647 +102636421 Gm21740 MGI:MGI:5433904 +102636422 Gm21826 MGI:MGI:5433990 +102636423 Gm21875 MGI:MGI:5434039 +102636424 Gm33489 MGI:MGI:5592648 +102636425 Gm33490 MGI:MGI:5592649 +102636426 Gm33491 MGI:MGI:5592650 +102636427 Gm33492 MGI:MGI:5592651 +102636429 Gm33494 MGI:MGI:5592653 +102636431 Gm33496 MGI:MGI:5592655 +102636432 Gm33497 MGI:MGI:5592656 +102636435 Gm33500 MGI:MGI:5592659 +102636436 Gm26730 MGI:MGI:5477224|Ensembl:ENSMUSG00000097117 +102636438 Gm33501 MGI:MGI:5592660|Ensembl:ENSMUSG00000110000 +102636439 Gm33502 MGI:MGI:5592661 +102636440 Gm33503 MGI:MGI:5592662 +102636441 Gm33504 MGI:MGI:5592663 +102636442 Gm33505 MGI:MGI:5592664 +102636445 Gm33508 MGI:MGI:5592667 +102636446 Gm33509 MGI:MGI:5592668 +102636447 Gm33510 MGI:MGI:5592669 +102636449 Gm33511 MGI:MGI:5592670 +102636450 Gm33512 MGI:MGI:5592671 +102636451 Gm9877 MGI:MGI:3708538 +102636452 Gm14450 MGI:MGI:3651431 +102636453 Gm33513 MGI:MGI:5592672 +102636454 Gm33514 MGI:MGI:5592673 +102636455 Gm33515 MGI:MGI:5592674 +102636456 Gm21832 MGI:MGI:5433996 +102636457 Gm33516 MGI:MGI:5592675 +102636458 Gm33517 MGI:MGI:5592676 +102636460 Gm33519 MGI:MGI:5592678 +102636462 LOC102636462 - +102636463 Gm38488 MGI:MGI:5621373 +102636464 Gm33521 MGI:MGI:5592680 +102636467 Gm33524 MGI:MGI:5592683 +102636468 Gm33525 MGI:MGI:5592684 +102636470 Gm33527 MGI:MGI:5592686 +102636471 Gm33528 MGI:MGI:5592687 +102636473 Gm33530 MGI:MGI:5592689 +102636474 Gm33531 MGI:MGI:5592690 +102636475 Gm33532 MGI:MGI:5592691 +102636476 Gm33533 MGI:MGI:5592692 +102636477 Gm26632 MGI:MGI:5477126 +102636478 LOC102636478 - +102636479 Gm33534 MGI:MGI:5592693 +102636480 Gm33535 MGI:MGI:5592694 +102636481 Gm33536 MGI:MGI:5592695 +102636482 Gm33537 MGI:MGI:5592696 +102636483 Gm33538 MGI:MGI:5592697 +102636484 Gm33539 MGI:MGI:5592698 +102636485 Gm12414 MGI:MGI:3650374 +102636486 Gm33540 MGI:MGI:5592699 +102636487 Gm33541 MGI:MGI:5592700 +102636490 Gm33542 MGI:MGI:5592701 +102636491 Gm33543 MGI:MGI:5592702|Ensembl:ENSMUSG00000110353|Vega:OTTMUSG00000060265 +102636492 Gm33544 MGI:MGI:5592703 +102636494 Gm14862 MGI:MGI:3705234 +102636496 Gm33547 MGI:MGI:5592706 +102636497 Gm29258 MGI:MGI:5579964 +102636498 Gm33548 MGI:MGI:5592707 +102636500 Gm12829 MGI:MGI:3650003 +102636501 Gm28961 MGI:MGI:5579667 +102636502 Gm21790 MGI:MGI:5433954 +102636504 Gm33551 MGI:MGI:5592710 +102636505 Gm33552 MGI:MGI:5592711 +102636507 Gm33553 MGI:MGI:5592712 +102636508 Gm33554 MGI:MGI:5592713 +102636509 Gm8020 MGI:MGI:3647991 +102636510 Gm33555 MGI:MGI:5592714 +102636512 Gm33557 MGI:MGI:5592716 +102636514 Uph Ensembl:ENSMUSG00000100510 +102636515 Gm33558 MGI:MGI:5592717 +102636516 Gm15742 MGI:MGI:3783184 +102636517 Gm33559 MGI:MGI:5592718 +102636518 Gm33560 MGI:MGI:5592719 +102636519 Gm33561 MGI:MGI:5592720 +102636520 Gm33562 MGI:MGI:5592721 +102636521 Gm33563 MGI:MGI:5592722 +102636522 Gm33564 MGI:MGI:5592723 +102636523 Gm33565 MGI:MGI:5592724 +102636524 Gm33566 MGI:MGI:5592725 +102636528 Gm33570 MGI:MGI:5592729 +102636529 Gm28089 MGI:MGI:5578795 +102636530 LOC102636530 - +102636532 Gm33571 MGI:MGI:5592730 +102636534 Gm33573 MGI:MGI:5592732 +102636536 Gm33574 MGI:MGI:5592733 +102636537 Gm33575 MGI:MGI:5592734 +102636539 Gm33576 MGI:MGI:5592735 +102636540 Gm15325 MGI:MGI:3705151|Ensembl:ENSMUSG00000086861 +102636541 Gm33577 MGI:MGI:5592736 +102636542 Gm33578 MGI:MGI:5592737 +102636543 Gm33579 MGI:MGI:5592738 +102636544 Gm33580 MGI:MGI:5592739 +102636545 Gm33581 MGI:MGI:5592740 +102636546 Gm33582 MGI:MGI:5592741 +102636547 Gm33583 MGI:MGI:5592742 +102636548 Gm33584 MGI:MGI:5592743 +102636549 Gm33585 MGI:MGI:5592744 +102636550 Gm33586 MGI:MGI:5592745 +102636551 LOC102636551 - +102636552 Gm33587 MGI:MGI:5592746 +102636553 Gm33588 MGI:MGI:5592747 +102636554 Als2cr11b MGI:MGI:5592748 +102636555 Gm29611 MGI:MGI:5580317 +102636556 Gm33590 MGI:MGI:5592749 +102636557 Gm33591 MGI:MGI:5592750 +102636558 LOC102636558 - +102636559 Gm33592 MGI:MGI:5592751 +102636560 Gm33593 MGI:MGI:5592752 +102636561 Gm13530 MGI:MGI:3651890 +102636562 Gm33594 MGI:MGI:5592753 +102636563 LOC102636563 - +102636564 Gm33595 MGI:MGI:5592754 +102636565 Gm33596 MGI:MGI:5592755 +102636566 Gm10103 MGI:MGI:3643505 +102636567 Gm33597 MGI:MGI:5592756 +102636568 Gm33598 MGI:MGI:5592757 +102636569 Gm13794 MGI:MGI:3652242 +102636570 Gm33599 MGI:MGI:5592758 +102636571 Gm13029 MGI:MGI:3651764 +102636574 Gm33601 MGI:MGI:5592760 +102636575 Gm33602 MGI:MGI:5592761 +102636577 Gm33604 MGI:MGI:5592763 +102636578 Gm33605 MGI:MGI:5592764 +102636579 Gm10298 MGI:MGI:3642777 +102636580 Gm28248 MGI:MGI:5578954 +102636581 LOC102636581 - +102636582 Gm26555 MGI:MGI:5477049 +102636583 Gm33606 MGI:MGI:5592765 +102636584 Gm38489 MGI:MGI:5621374 +102636585 Gm33607 MGI:MGI:5592766 +102636586 Gm33608 MGI:MGI:5592767 +102636587 Gm33609 MGI:MGI:5592768 +102636589 Gm15807 MGI:MGI:3802044 +102636590 LOC102636590 - +102636591 Gm33610 MGI:MGI:5592769 +102636592 Gm33611 MGI:MGI:5592770 +102636593 Gm33612 MGI:MGI:5592771 +102636594 Gm33613 MGI:MGI:5592772 +102636595 Gm33614 MGI:MGI:5592773 +102636596 Gm33615 MGI:MGI:5592774 +102636597 Gm33616 MGI:MGI:5592775 +102636598 Gm33617 MGI:MGI:5592776 +102636599 Gm33618 MGI:MGI:5592777 +102636600 Gm33619 MGI:MGI:5592778|Ensembl:ENSMUSG00000111005 +102636601 Gm33620 MGI:MGI:5592779 +102636602 Gm12496 MGI:MGI:3650573 +102636603 Gm33621 MGI:MGI:5592780 +102636604 Gm33622 MGI:MGI:5592781 +102636605 Gm33623 MGI:MGI:5592782 +102636606 Gm33624 MGI:MGI:5592783 +102636608 Gm33626 MGI:MGI:5592785 +102636609 Scgb1b13-ps MGI:MGI:5578739 +102636610 Gm20652 MGI:MGI:5313099 +102636611 Gm33627 MGI:MGI:5592786 +102636612 Gm33628 MGI:MGI:5592787 +102636613 Gm28291 MGI:MGI:5578997|Ensembl:ENSMUSG00000100227 +102636615 Gm11345 MGI:MGI:3649367 +102636616 Gm20904 MGI:MGI:5434260 +102636617 Gm21782 MGI:MGI:5433946 +102636618 Gm33630 MGI:MGI:5592789|Ensembl:ENSMUSG00000113276 +102636619 Gm33631 MGI:MGI:5592790 +102636620 Gm15326 MGI:MGI:3705205|Ensembl:ENSMUSG00000086111 +102636621 Gm33632 MGI:MGI:5592791 +102636622 Gm33633 MGI:MGI:5592792 +102636623 Gm33634 MGI:MGI:5592793 +102636624 Gm33635 MGI:MGI:5592794 +102636625 Gm33636 MGI:MGI:5592795 +102636626 Gm33637 MGI:MGI:5592796 +102636627 Gm33638 MGI:MGI:5592797 +102636629 Gm33640 MGI:MGI:5592799 +102636630 Gm33641 MGI:MGI:5592800 +102636631 Gm38490 MGI:MGI:5621375 +102636632 Gm33642 MGI:MGI:5592801 +102636633 Gm33643 MGI:MGI:5592802 +102636634 Gm33644 MGI:MGI:5592803 +102636635 Gm33645 MGI:MGI:5592804 +102636636 Gm33646 MGI:MGI:5592805 +102636637 Gm33647 MGI:MGI:5592806 +102636638 Gm13799 MGI:MGI:3652037|Ensembl:ENSMUSG00000087537 +102636639 Gm33648 MGI:MGI:5592807 +102636640 Gm33649 MGI:MGI:5592808 +102636641 Gm26618 MGI:MGI:5477112 +102636642 Gm33650 MGI:MGI:5592809 +102636643 Gm33651 MGI:MGI:5592810 +102636645 Gm33653 MGI:MGI:5592812 +102636646 Gm33654 MGI:MGI:5592813 +102636647 Gm33655 MGI:MGI:5592814 +102636648 Gm33656 MGI:MGI:5592815 +102636649 Gm28392 MGI:MGI:5579098 +102636652 Gm16261 MGI:MGI:3826544 +102636654 Gm33659 MGI:MGI:5592818 +102636655 Gm33660 MGI:MGI:5592819 +102636656 Gm33661 MGI:MGI:5592820 +102636657 Gm33662 MGI:MGI:5592821 +102636658 Gm33663 MGI:MGI:5592822 +102636660 Gm33665 MGI:MGI:5592824 +102636661 Gm33666 MGI:MGI:5592825 +102636662 Gm33667 MGI:MGI:5592826 +102636663 Gm33668 MGI:MGI:5592827 +102636664 LOC102636664 - +102636665 Gm33669 MGI:MGI:5592828 +102636666 LOC102636666 - +102636667 Gm33670 MGI:MGI:5592829 +102636668 Gm33671 MGI:MGI:5592830 +102636669 Gm33672 MGI:MGI:5592831 +102636671 Gm33674 MGI:MGI:5592833 +102636672 Gm33675 MGI:MGI:5592834 +102636673 Gm33676 MGI:MGI:5592835 +102636674 Gm33677 MGI:MGI:5592836|Ensembl:ENSMUSG00000112778 +102636675 Gm33678 MGI:MGI:5592837 +102636676 Gm33679 MGI:MGI:5592838 +102636677 Gm33680 MGI:MGI:5592839|Ensembl:ENSMUSG00000112054 +102636679 Gm33682 MGI:MGI:5592841 +102636681 Gm11342 MGI:MGI:3652098 +102636682 Gm33684 MGI:MGI:5592843 +102636685 Gm33687 MGI:MGI:5592846 +102636687 Gm33688 MGI:MGI:5592847 +102636689 Gm33690 MGI:MGI:5592849 +102636690 Gm33691 MGI:MGI:5592850 +102636691 Gm29243 MGI:MGI:5579949|Ensembl:ENSMUSG00000100605 +102636692 Gm33692 MGI:MGI:5592851 +102636693 Gm33693 MGI:MGI:5592852 +102636694 Gm33694 MGI:MGI:5592853 +102636695 Gm33695 MGI:MGI:5592854 +102636696 Gm33696 MGI:MGI:5592855 +102636697 Gm33697 MGI:MGI:5592856 +102636698 Gm33698 MGI:MGI:5592857 +102636699 Gm33699 MGI:MGI:5592858 +102636700 LOC102636700 - +102636701 Gm33700 MGI:MGI:5592859 +102636702 Gm28111 MGI:MGI:5578817|Ensembl:ENSMUSG00000101411 +102636703 Gm33701 MGI:MGI:5592860 +102636704 Gm33702 MGI:MGI:5592861 +102636705 Gm33703 MGI:MGI:5592862 +102636706 Gm33704 MGI:MGI:5592863 +102636707 LOC102636707 - +102636708 Gm33705 MGI:MGI:5592864 +102636709 Mypopos MGI:MGI:3826523|Ensembl:ENSMUSG00000086533 +102636711 Gm33707 MGI:MGI:5592866 +102636712 Gm33708 MGI:MGI:5592867 +102636714 Gm33710 MGI:MGI:5592869 +102636716 Gm33712 MGI:MGI:5592871 +102636718 Gm29062 MGI:MGI:5579768 +102636719 Gm15374 MGI:MGI:3707463 +102636721 Gm33714 MGI:MGI:5592873 +102636722 Gm33715 MGI:MGI:5592874 +102636723 Gm33716 MGI:MGI:5592875 +102636727 Gm33719 MGI:MGI:5592878 +102636728 Gm33720 MGI:MGI:5592879 +102636729 Gm33721 MGI:MGI:5592880 +102636731 Gm33723 MGI:MGI:5592882 +102636732 Gm33724 MGI:MGI:5592883 +102636733 LOC102636733 - +102636734 LOC102636734 - +102636735 Gm33725 MGI:MGI:5592884 +102636736 Gm33726 MGI:MGI:5592885 +102636737 Gm33727 MGI:MGI:5592886 +102636738 Gm33728 MGI:MGI:5592887 +102636739 Gm33729 MGI:MGI:5592888 +102636740 Gm33730 MGI:MGI:5592889 +102636741 LOC102636741 - +102636743 Gm33732 MGI:MGI:5592891 +102636745 Gm33733 MGI:MGI:5592892 +102636746 Gm33734 MGI:MGI:5592893 +102636748 Gm28171 MGI:MGI:5578877 +102636750 Gm33736 MGI:MGI:5592895 +102636751 Gm33737 MGI:MGI:5592896 +102636753 Gm29204 MGI:MGI:5579910|Ensembl:ENSMUSG00000099836 +102636754 Gm33738 MGI:MGI:5592897 +102636755 Gm15323 MGI:MGI:3705285 +102636756 Gm16177 MGI:MGI:3801751 +102636757 Gm33739 MGI:MGI:5592898 +102636758 Gm33740 MGI:MGI:5592899 +102636759 Gm33741 MGI:MGI:5592900 +102636760 Gm33742 MGI:MGI:5592901 +102636761 Gm33743 MGI:MGI:5592902 +102636763 Gm33745 MGI:MGI:5592904 +102636764 Gm29536 MGI:MGI:5580242|Ensembl:ENSMUSG00000099706 +102636765 Gm33746 MGI:MGI:5592905 +102636766 Gm33747 MGI:MGI:5592906 +102636768 Gm33748 MGI:MGI:5592907 +102636769 Gm33749 MGI:MGI:5592908 +102636770 Gm33750 MGI:MGI:5592909 +102636772 Gm33751 MGI:MGI:5592910 +102636773 Gm33752 MGI:MGI:5592911 +102636774 Gm33753 MGI:MGI:5592912 +102636775 Gm33754 MGI:MGI:5592913 +102636776 LOC102636776 - +102636777 LOC102636777 - +102636778 Gm33755 MGI:MGI:5592914 +102636779 Gm33756 MGI:MGI:5592915 +102636781 Gm16069 MGI:MGI:3801823 +102636782 Gm33758 MGI:MGI:5592917 +102636783 Gm33759 MGI:MGI:5592918 +102636784 LOC102636784 - +102636785 Gm33760 MGI:MGI:5592919 +102636786 Gm28290 MGI:MGI:5578996 +102636789 Gm33763 MGI:MGI:5592922 +102636790 Gm33764 MGI:MGI:5592923 +102636791 Gm33765 MGI:MGI:5592924 +102636792 LOC102636792 Ensembl:ENSMUSG00000094578 +102636793 Gm33766 MGI:MGI:5592925 +102636794 Gm33767 MGI:MGI:5592926 +102636795 LOC102636795 - +102636797 Gm33769 MGI:MGI:5592928 +102636798 Gm33770 MGI:MGI:5592929 +102636799 Gm33771 MGI:MGI:5592930 +102636800 Gm33772 MGI:MGI:5592931 +102636802 Gm33774 MGI:MGI:5592933 +102636803 Gm15496 MGI:MGI:3782942 +102636805 Gm33776 MGI:MGI:5592935 +102636806 Gm33777 MGI:MGI:5592936 +102636807 Gm33778 MGI:MGI:5592937 +102636808 Gm38491 MGI:MGI:5621376 +102636809 Gm33779 MGI:MGI:5592938 +102636811 Gm33780 MGI:MGI:5592939 +102636812 Gm33781 MGI:MGI:5592940 +102636813 Gm33782 MGI:MGI:5592941 +102636815 LOC102636815 - +102636816 Scgb2b14-ps MGI:MGI:5578750 +102636818 Gm33784 MGI:MGI:5592943 +102636819 Gm33785 MGI:MGI:5592944 +102636820 Gm33786 MGI:MGI:5592945 +102636821 Gm28255 MGI:MGI:5578961 +102636822 Gm28219 MGI:MGI:5578925 +102636823 Gm28888 MGI:MGI:5579594 +102636824 Gm33787 MGI:MGI:5592946 +102636825 Gm33788 MGI:MGI:5592947 +102636826 Gm15322 MGI:MGI:3705208 +102636827 Gm33789 MGI:MGI:5592948 +102636828 LOC102636828 - +102636830 Gm33790 MGI:MGI:5592949 +102636831 Gm33791 MGI:MGI:5592950 +102636833 Gm33793 MGI:MGI:5592952 +102636834 Gm33794 MGI:MGI:5592953 +102636835 Gm33795 MGI:MGI:5592954 +102636836 Gm17202 MGI:MGI:4938029 +102636838 Gm33797 MGI:MGI:5592956 +102636839 Gm33798 MGI:MGI:5592957 +102636840 Gm33799 MGI:MGI:5592958 +102636841 LOC102636841 - +102636843 Gm33800 MGI:MGI:5592959 +102636844 Gm16049 MGI:MGI:3802073 +102636845 Gm33801 MGI:MGI:5592960 +102636846 Gm33802 MGI:MGI:5592961 +102636847 Gm33803 MGI:MGI:5592962 +102636848 Gm33804 MGI:MGI:5592963 +102636849 Gm14170 MGI:MGI:3650933 +102636850 Gm33805 MGI:MGI:5592964 +102636851 Gm33806 MGI:MGI:5592965 +102636855 Gm33809 MGI:MGI:5592968 +102636856 Gm33810 MGI:MGI:5592969 +102636857 Gm28916 MGI:MGI:5579622 +102636858 Gm33811 MGI:MGI:5592970 +102636860 Gm33813 MGI:MGI:5592972 +102636861 Gm33814 MGI:MGI:5592973 +102636862 Gm33815 MGI:MGI:5592974 +102636864 Gm33817 MGI:MGI:5592976 +102636865 Gm33818 MGI:MGI:5592977 +102636866 Gm33819 MGI:MGI:5592978 +102636867 Gm33820 MGI:MGI:5592979 +102636868 Gm33821 MGI:MGI:5592980 +102636870 Gm27167 MGI:MGI:5521010 +102636872 Gm33823 MGI:MGI:5592982 +102636873 LOC102636873 - +102636874 Gm33824 MGI:MGI:5592983 +102636875 Gm33825 MGI:MGI:5592984 +102636876 Gm33826 MGI:MGI:5592985 +102636877 Gm33827 MGI:MGI:5592986 +102636878 Gm33828 MGI:MGI:5592987 +102636879 Gm33829 MGI:MGI:5592988 +102636880 Gm33830 MGI:MGI:5592989 +102636881 Gm33831 MGI:MGI:5592990 +102636882 Gm33832 MGI:MGI:5592991 +102636883 Gm33833 MGI:MGI:5592992 +102636884 Gm33834 MGI:MGI:5592993 +102636886 Gm33836 MGI:MGI:5592995 +102636887 Gm33837 MGI:MGI:5592996 +102636888 Gm33838 MGI:MGI:5592997 +102636890 Gm12374 MGI:MGI:3652319|Ensembl:ENSMUSG00000086026 +102636891 Gm33840 MGI:MGI:5592999 +102636892 Gm33841 MGI:MGI:5593000 +102636893 Gm33842 MGI:MGI:5593001 +102636894 LOC102636894 - +102636895 Gm33843 MGI:MGI:5593002 +102636896 2410080I02Rik MGI:MGI:1915498 +102636897 Gm33844 MGI:MGI:5593003 +102636898 Gm33845 MGI:MGI:5593004 +102636900 LOC102636900 - +102636901 Gm33847 MGI:MGI:5593006|Ensembl:ENSMUSG00000105299 +102636903 Gm17039 MGI:MGI:4937866|Ensembl:ENSMUSG00000092103 +102636904 Gm33849 MGI:MGI:5593008 +102636905 Gm26908 MGI:MGI:5477402 +102636907 LOC102636907 - +102636909 Gm33851 MGI:MGI:5593010 +102636910 Gm33852 MGI:MGI:5593011 +102636913 Gm33855 MGI:MGI:5593014 +102636915 Gm33856 MGI:MGI:5593015 +102636916 Gm33857 MGI:MGI:5593016 +102636917 Gm33858 MGI:MGI:5593017 +102636919 Gm15199 MGI:MGI:3705141 +102636920 Gm33860 MGI:MGI:5593019 +102636922 Gm33861 MGI:MGI:5593020 +102636923 Gm33862 MGI:MGI:5593021 +102636925 Scgb2b31-ps MGI:MGI:5578754 +102636926 Gm33864 MGI:MGI:5593023 +102636928 Gm33866 MGI:MGI:5593025 +102636929 Gm33867 MGI:MGI:5593026 +102636930 Gm33868 MGI:MGI:5593027 +102636931 Gm33869 MGI:MGI:5593028 +102636932 Gm28249 MGI:MGI:5578955 +102636934 Gm12707 MGI:MGI:3652172 +102636938 Gm21796 MGI:MGI:5433960 +102636939 Gm33873 MGI:MGI:5593032 +102636940 Gm28209 MGI:MGI:5578915 +102636941 Gm33874 MGI:MGI:5593033 +102636942 Gm33875 MGI:MGI:5593034 +102636944 Gm33877 MGI:MGI:5593036 +102636945 Gm26747 MGI:MGI:5477241 +102636947 Gm33878 MGI:MGI:5593037 +102636948 LOC102636948 - +102636949 LOC102636949 - +102636950 Gm33879 MGI:MGI:5593038 +102636951 Gm33880 MGI:MGI:5593039 +102636953 Gm33882 MGI:MGI:5593041 +102636957 Gm28411 MGI:MGI:5579117 +102636958 Gm28650 MGI:MGI:5579356 +102636959 Gm33885 MGI:MGI:5593044 +102636960 Gm28071 MGI:MGI:5578777 +102636961 Gm33886 MGI:MGI:5593045 +102636962 Gm33887 MGI:MGI:5593046 +102636963 Gm33888 MGI:MGI:5593047 +102636964 Gm33889 MGI:MGI:5593048 +102636965 Gm33890 MGI:MGI:5593049 +102636966 Gm33891 MGI:MGI:5593050 +102636967 Gm33892 MGI:MGI:5593051 +102636968 Gm12381 MGI:MGI:3651851|Ensembl:ENSMUSG00000085632 +102636969 Gm33893 MGI:MGI:5593052 +102636970 Gm33894 MGI:MGI:5593053 +102636971 Gm33895 MGI:MGI:5593054 +102636972 Gm33896 MGI:MGI:5593055 +102636973 Gm33897 MGI:MGI:5593056 +102636974 Gm33898 MGI:MGI:5593057 +102636976 Gm21719 MGI:MGI:5433883 +102636978 Gm33901 MGI:MGI:5593060 +102636980 Gm29538 MGI:MGI:5580244 +102636981 Gm33903 MGI:MGI:5593062 +102636982 Gm33904 MGI:MGI:5593063 +102636983 Gm33905 MGI:MGI:5593064 +102636984 Gm33906 MGI:MGI:5593065 +102636986 Gm15755 MGI:MGI:3783198 +102636988 LOC102636988 - +102636989 LOC102636989 Ensembl:ENSMUSG00000031085|Vega:OTTMUSG00000033773 +102636990 Gm33908 MGI:MGI:5593067 +102636991 Gm33909 MGI:MGI:5593068 +102636992 Gm33910 MGI:MGI:5593069 +102636993 Gm33911 MGI:MGI:5593070 +102636994 Gm33912 MGI:MGI:5593071 +102636996 Gm33914 MGI:MGI:5593073|Ensembl:ENSMUSG00000111354 +102636998 Gm33915 MGI:MGI:5593074 +102636999 Gm33916 MGI:MGI:5593075 +102637001 LOC102637001 - +102637003 Gm33919 MGI:MGI:5593078 +102637005 Gm12069 MGI:MGI:3649875|Ensembl:ENSMUSG00000086439 +102637006 Gm33921 MGI:MGI:5593080 +102637007 Gm33922 MGI:MGI:5593081 +102637008 Gm33923 MGI:MGI:5593082 +102637009 Gm33924 MGI:MGI:5593083 +102637010 Gm33925 MGI:MGI:5593084 +102637011 Gm33926 MGI:MGI:5593085 +102637012 LOC102637012 MGI:MGI:5593086 +102637013 Gm21809 MGI:MGI:5433973 +102637015 Gm33929 MGI:MGI:5593088 +102637016 Gm29577 MGI:MGI:5580283 +102637018 Gm33931 MGI:MGI:5593090 +102637019 Gm33932 MGI:MGI:5593091 +102637020 Gm33933 MGI:MGI:5593092 +102637021 LOC102637021 - +102637022 Gm33934 MGI:MGI:5593093 +102637023 Gm33935 MGI:MGI:5593094 +102637024 Gm33936 MGI:MGI:5593095 +102637025 Gm33937 MGI:MGI:5593096 +102637026 Gm33938 MGI:MGI:5593097 +102637027 Gm33939 MGI:MGI:5593098 +102637028 Gm33940 MGI:MGI:5593099 +102637030 Gm33941 MGI:MGI:5593100 +102637031 Gm33942 MGI:MGI:5593101 +102637033 Gm33944 MGI:MGI:5593103 +102637034 Gm33945 MGI:MGI:5593104 +102637035 Gm17094 MGI:MGI:4937921 +102637036 Gm33946 MGI:MGI:5593105 +102637037 Gm33947 MGI:MGI:5593106 +102637038 Banf2os MGI:MGI:3650982 +102637039 Gm33948 MGI:MGI:5593107 +102637041 Gm33950 MGI:MGI:5593109 +102637042 Gm33951 MGI:MGI:5593110 +102637043 Gm33952 MGI:MGI:5593111 +102637044 Gm33953 MGI:MGI:5593112 +102637045 Gm33954 MGI:MGI:5593113 +102637046 Gm33955 MGI:MGI:5593114 +102637048 Gm38492 MGI:MGI:5621377 +102637049 Gm38493 MGI:MGI:5621378 +102637050 Gm33957 MGI:MGI:5593116 +102637051 Gm29299 MGI:MGI:5580005 +102637052 Gm33958 MGI:MGI:5593117 +102637053 Gm33959 MGI:MGI:5593118 +102637055 Gm33961 MGI:MGI:5593120 +102637056 Gm33962 MGI:MGI:5593121 +102637057 Gm33963 MGI:MGI:5593122 +102637058 Gm33964 MGI:MGI:5593123 +102637059 Gm11730 MGI:MGI:3650941 +102637061 Gm33966 MGI:MGI:5593125 +102637062 Gm33967 MGI:MGI:5593126 +102637063 Gm33968 MGI:MGI:5593127 +102637064 Gm33969 MGI:MGI:5593128|Ensembl:ENSMUSG00000104717 +102637066 Gm33970 MGI:MGI:5593129 +102637067 Gm33971 MGI:MGI:5593130 +102637068 Gm33972 MGI:MGI:5593131 +102637069 Gm33973 MGI:MGI:5593132 +102637070 LOC102637070 Ensembl:ENSMUSG00000068071 +102637071 Gm33974 MGI:MGI:5593133 +102637074 Gm13561 MGI:MGI:3651674 +102637075 Gm33977 MGI:MGI:5593136 +102637077 Gm33979 MGI:MGI:5593138 +102637078 Gm33980 MGI:MGI:5593139 +102637079 Gm33981 MGI:MGI:5593140 +102637080 Gm33982 MGI:MGI:5593141 +102637081 Gm33983 MGI:MGI:5593142 +102637082 Gm33984 MGI:MGI:5593143 +102637083 Gm33985 MGI:MGI:5593144 +102637085 Gm33987 MGI:MGI:5593146 +102637086 Gm33988 MGI:MGI:5593147 +102637087 Gm33989 MGI:MGI:5593148 +102637088 Gm33990 MGI:MGI:5593149 +102637089 Gm33991 MGI:MGI:5593150 +102637091 Gm28193 MGI:MGI:5578899 +102637092 Gm21872 MGI:MGI:5434036 +102637093 Gm33993 MGI:MGI:5593152 +102637094 LOC102637094 - +102637095 Gm33994 MGI:MGI:5593153 +102637096 Gm33995 MGI:MGI:5593154 +102637097 Gm38494 MGI:MGI:5621379 +102637099 Gm38495 MGI:MGI:5621380 +102637100 Gm26911 MGI:MGI:5477405 +102637101 Gm33997 MGI:MGI:5593156 +102637102 Gm33998 MGI:MGI:5593157 +102637104 Gm34000 MGI:MGI:5593159 +102637105 Gm34001 MGI:MGI:5593160 +102637106 Gm34002 MGI:MGI:5593161 +102637107 Ptf1aos MGI:MGI:3651438|Ensembl:ENSMUSG00000085388 +102637108 Gm34003 MGI:MGI:5593162 +102637109 Gm34004 MGI:MGI:5593163 +102637110 Gm34005 MGI:MGI:5593164 +102637111 Gm20541 MGI:MGI:5142006 +102637112 Gm34006 MGI:MGI:5593165 +102637113 Gm34007 MGI:MGI:5593166 +102637114 Gm34008 MGI:MGI:5593167 +102637116 Gm34010 MGI:MGI:5593169 +102637118 Gm34011 MGI:MGI:5593170 +102637119 Gm34012 MGI:MGI:5593171 +102637120 Gm34013 MGI:MGI:5593172 +102637122 Gm34014 MGI:MGI:5593173 +102637123 Gm34015 MGI:MGI:5593174 +102637124 Gm21871 MGI:MGI:5434035 +102637125 Gm28243 MGI:MGI:5578949 +102637126 Gm34016 MGI:MGI:5593175 +102637127 Gm34017 MGI:MGI:5593176 +102637129 LOC102637129 - +102637130 Gm21241 MGI:MGI:5434596 +102637131 Gm12976 MGI:MGI:3650499 +102637132 Gm34019 MGI:MGI:5593178 +102637133 Gm34020 MGI:MGI:5593179 +102637135 Gm34022 MGI:MGI:5593181 +102637136 Gm34023 MGI:MGI:5593182 +102637137 Gm34024 MGI:MGI:5593183 +102637139 Gm34025 MGI:MGI:5593184 +102637140 Gm34026 MGI:MGI:5593185 +102637142 Gm12326 MGI:MGI:3651350 +102637143 Gm34027 MGI:MGI:5593186 +102637144 Gm34028 MGI:MGI:5593187 +102637145 Gm34029 MGI:MGI:5593188 +102637146 Gm34030 MGI:MGI:5593189 +102637147 Gm34031 MGI:MGI:5593190 +102637148 Gm34032 MGI:MGI:5593191 +102637149 Gm34033 MGI:MGI:5593192 +102637151 Gm34035 MGI:MGI:5593194 +102637152 Gm34036 MGI:MGI:5593195 +102637153 Gm34037 MGI:MGI:5593196 +102637154 Gm34038 MGI:MGI:5593197 +102637155 Gm34039 MGI:MGI:5593198 +102637157 Gm34041 MGI:MGI:5593200 +102637158 Gm34042 MGI:MGI:5593201 +102637159 Gm34043 MGI:MGI:5593202 +102637160 Gm34044 MGI:MGI:5593203 +102637161 Gm34045 MGI:MGI:5593204 +102637162 Gm34046 MGI:MGI:5593205 +102637163 LOC102637163 Ensembl:ENSMUSG00000101232|Vega:OTTMUSG00000045781 +102637164 Gm34047 MGI:MGI:5593206 +102637165 Gm34048 MGI:MGI:5593207 +102637166 Gm34049 MGI:MGI:5593208 +102637167 Gm34050 MGI:MGI:5593209 +102637169 Gm34052 MGI:MGI:5593211 +102637171 Gm34053 MGI:MGI:5593212 +102637173 Gm28637 MGI:MGI:5579343 +102637174 Gm29178 MGI:MGI:5579884 +102637175 Gm28368 MGI:MGI:5579074 +102637176 Gm34055 MGI:MGI:5593214 +102637177 Gm34056 MGI:MGI:5593215 +102637178 Gm34057 MGI:MGI:5593216 +102637179 Gm34058 MGI:MGI:5593217 +102637181 Gm38496 MGI:MGI:5621381 +102637182 Gm34059 MGI:MGI:5593218 +102637183 Gm34060 MGI:MGI:5593219 +102637184 Gm34061 MGI:MGI:5593220 +102637185 Gm34062 MGI:MGI:5593221 +102637187 Gm34064 MGI:MGI:5593223 +102637188 Gm34065 MGI:MGI:5593224 +102637189 Gm34066 MGI:MGI:5593225 +102637190 Gm34067 MGI:MGI:5593226 +102637191 Gm34068 MGI:MGI:5593227|Ensembl:ENSMUSG00000103305 +102637192 LOC102637192 Ensembl:ENSMUSG00000059113|Vega:OTTMUSG00000046462 +102637193 Gm13348 MGI:MGI:3649255 +102637194 Gm34069 MGI:MGI:5593228 +102637195 Gm15565 MGI:MGI:3783014 +102637196 Gm34070 MGI:MGI:5593229 +102637197 Gm34071 MGI:MGI:5593230 +102637198 Gm34072 MGI:MGI:5593231 +102637199 Gm34073 MGI:MGI:5593232 +102637200 LOC102637200 - +102637201 Gm34074 MGI:MGI:5593233 +102637202 Gm34075 MGI:MGI:5593234 +102637203 Gm34076 MGI:MGI:5593235 +102637204 Gm34077 MGI:MGI:5593236 +102637205 Gm34078 MGI:MGI:5593237 +102637206 Gm34079 MGI:MGI:5593238 +102637207 Gm28442 MGI:MGI:5579148 +102637208 Gm34080 MGI:MGI:5593239 +102637209 Gm34081 MGI:MGI:5593240 +102637210 Gm21898 MGI:MGI:5434062 +102637211 Gm34082 MGI:MGI:5593241 +102637213 Gm34084 MGI:MGI:5593243 +102637215 Gm20647 MGI:MGI:5313094 +102637216 Gm34086 MGI:MGI:5593245 +102637217 Gm34087 MGI:MGI:5593246 +102637219 LOC102637219 - +102637220 Gm34089 MGI:MGI:5593248 +102637221 Gm34090 MGI:MGI:5593249 +102637222 Gm34091 MGI:MGI:5593250 +102637223 Gm34092 MGI:MGI:5593251 +102637224 Gm34093 MGI:MGI:5593252 +102637225 Gm34094 MGI:MGI:5593253 +102637226 Gm34095 MGI:MGI:5593254 +102637227 Gm34096 MGI:MGI:5593255 +102637228 Gm34097 MGI:MGI:5593256 +102637229 Gm34098 MGI:MGI:5593257 +102637230 Gm34099 MGI:MGI:5593258|Ensembl:ENSMUSG00000109629 +102637231 Gm34100 MGI:MGI:5593259 +102637232 Gm34101 MGI:MGI:5593260 +102637233 Gm34102 MGI:MGI:5593261 +102637234 LOC102637234 - +102637235 Gm34103 MGI:MGI:5593262 +102637237 Gm34105 MGI:MGI:5593264|Ensembl:ENSMUSG00000111449 +102637238 Gm27234 MGI:MGI:5521077 +102637239 Gm34106 MGI:MGI:5593265 +102637240 Gm34107 MGI:MGI:5593266 +102637243 Gm34110 MGI:MGI:5593269 +102637244 Gm13919 MGI:MGI:3651616 +102637245 Gm34111 MGI:MGI:5593270 +102637246 Gm34112 MGI:MGI:5593271 +102637247 Gm34113 MGI:MGI:5593272 +102637248 Gm34114 MGI:MGI:5593273 +102637250 Gm11946 MGI:MGI:3650071 +102637251 Gm34116 MGI:MGI:5593275 +102637253 Gm34118 MGI:MGI:5593277 +102637254 Gm34119 MGI:MGI:5593278 +102637256 Gm34121 MGI:MGI:5593280 +102637257 Gm28280 MGI:MGI:5578986|Ensembl:ENSMUSG00000100953 +102637258 Gm34122 MGI:MGI:5593281 +102637261 Gm27246 MGI:MGI:5521089 +102637262 Gm34125 MGI:MGI:5593284 +102637264 Gm12132 MGI:MGI:3651510|Ensembl:ENSMUSG00000085301 +102637265 Gm29507 MGI:MGI:5580213 +102637266 Gm34127 MGI:MGI:5593286 +102637267 Gm34128 MGI:MGI:5593287 +102637269 LOC102637269 - +102637270 Gm34130 MGI:MGI:5593289 +102637271 Gm34131 MGI:MGI:5593290 +102637272 Gm34132 MGI:MGI:5593291 +102637273 Gm34133 MGI:MGI:5593292 +102637276 Gm34136 MGI:MGI:5593295 +102637277 Gm21994 MGI:MGI:5439751 +102637278 LOC102637278 - +102637279 Gm13132 MGI:MGI:3651366 +102637280 Gm34137 MGI:MGI:5593296 +102637281 Gm26988 MGI:MGI:5504103 +102637282 Gm12082 MGI:MGI:3650549 +102637283 LOC102637283 - +102637284 Scgb2b16-ps MGI:MGI:5578751 +102637285 Gm34138 MGI:MGI:5593297 +102637287 Gm34139 MGI:MGI:5593298 +102637288 LOC102637288 - +102637289 Gm34140 MGI:MGI:5593299 +102637290 Gm15151 MGI:MGI:3705644 +102637294 Gm34143 MGI:MGI:5593302 +102637295 Gm29337 MGI:MGI:5580043 +102637296 Gm34144 MGI:MGI:5593303 +102637297 Gm34145 MGI:MGI:5593304 +102637298 Gm34146 MGI:MGI:5593305 +102637299 Gm20714 MGI:MGI:5313161|Ensembl:ENSMUSG00000093570 +102637300 Gm34147 MGI:MGI:5593306 +102637301 Gm34148 MGI:MGI:5593307 +102637302 Gm16976 MGI:MGI:4439900|Ensembl:ENSMUSG00000085500 +102637303 Gm34149 MGI:MGI:5593308 +102637304 Gm34150 MGI:MGI:5593309 +102637305 Gm12586 MGI:MGI:3649692 +102637307 Gm34152 MGI:MGI:5593311 +102637308 Gm34153 MGI:MGI:5593312 +102637309 Gm34154 MGI:MGI:5593313 +102637310 Gm34155 MGI:MGI:5593314 +102637311 Gm34156 MGI:MGI:5593315 +102637313 Gm34157 MGI:MGI:5593316 +102637314 Gm34158 MGI:MGI:5593317 +102637315 Gm34159 MGI:MGI:5593318 +102637316 Gm14249 MGI:MGI:3651257 +102637320 Gm34162 MGI:MGI:5593321 +102637322 LOC102637322 - +102637323 Gm29412 MGI:MGI:5580118 +102637325 Gm34165 MGI:MGI:5593324 +102637326 Gm28161 MGI:MGI:5578867 +102637329 Gm26812 MGI:MGI:5477306 +102637330 Gm34169 MGI:MGI:5593328 +102637331 Gm34170 MGI:MGI:5593329 +102637332 Gm34171 MGI:MGI:5593330 +102637333 Gm34172 MGI:MGI:5593331 +102637334 Gm34173 MGI:MGI:5593332 +102637335 Gm34174 MGI:MGI:5593333 +102637336 LOC102637336 - +102637337 Gm34175 MGI:MGI:5593334 +102637338 Gm28940 MGI:MGI:5579646 +102637339 Gm27005 MGI:MGI:5504120 +102637340 Gm34176 MGI:MGI:5593335 +102637341 Gm34177 MGI:MGI:5593336 +102637343 Gm34178 MGI:MGI:5593337 +102637344 Gm34179 MGI:MGI:5593338 +102637345 Gm34180 MGI:MGI:5593339 +102637346 Gm34181 MGI:MGI:5593340 +102637347 Gm34182 MGI:MGI:5593341 +102637348 Gm34183 MGI:MGI:5593342 +102637349 Gm34184 MGI:MGI:5593343|Ensembl:ENSMUSG00000111049 +102637350 Gm34185 MGI:MGI:5593344 +102637351 Gm34186 MGI:MGI:5593345 +102637352 Gm34187 MGI:MGI:5593346 +102637353 Gm34188 MGI:MGI:5593347 +102637354 LOC102637354 - +102637355 Gm34189 MGI:MGI:5593348 +102637356 Gm34190 MGI:MGI:5593349 +102637358 Gm21271 MGI:MGI:5434626 +102637359 Gm28598 MGI:MGI:5579304 +102637360 Gm34191 MGI:MGI:5593350 +102637361 Gm29476 MGI:MGI:5580182 +102637362 Gm34192 MGI:MGI:5593351 +102637363 Gm34193 MGI:MGI:5593352 +102637364 Gm34194 MGI:MGI:5593353 +102637366 Gm10037 MGI:MGI:3645096|Ensembl:ENSMUSG00000058246 +102637367 Gm34196 MGI:MGI:5593355 +102637368 Gm34197 MGI:MGI:5593356 +102637369 Gm34198 MGI:MGI:5593357 +102637370 Gm34199 MGI:MGI:5593358 +102637371 Gm15422 MGI:MGI:3707362 +102637373 Gm34201 MGI:MGI:5593360 +102637375 Gm34203 MGI:MGI:5593362 +102637376 Gm34204 MGI:MGI:5593363 +102637377 Gm34205 MGI:MGI:5593364 +102637378 Gm34206 MGI:MGI:5593365 +102637379 Gm34207 MGI:MGI:5593366 +102637380 Gm34208 MGI:MGI:5593367 +102637381 Gm17171 MGI:MGI:4937998 +102637382 Gm34209 MGI:MGI:5593368 +102637383 Gm34210 MGI:MGI:5593369 +102637384 Gm34211 MGI:MGI:5593370 +102637386 Gm34213 MGI:MGI:5593372 +102637387 Gm34214 MGI:MGI:5593373 +102637388 Gm14286 MGI:MGI:3650190 +102637389 Gm13021 MGI:MGI:3649637|Ensembl:ENSMUSG00000086437 +102637391 Scgb2b32-ps MGI:MGI:5578755 +102637392 Gm34215 MGI:MGI:5593374 +102637393 LOC102637393 - +102637395 Gm34217 MGI:MGI:5593376 +102637396 Gm28244 MGI:MGI:5578950 +102637397 Gm28522 MGI:MGI:5579228|Ensembl:ENSMUSG00000101681 +102637398 Gm34218 MGI:MGI:5593377 +102637400 Gm34220 MGI:MGI:5593379 +102637401 Gm29285 MGI:MGI:5579991 +102637404 Gm26008 MGI:MGI:5455785 +102637405 Gm34222 MGI:MGI:5593381 +102637406 Gm34223 MGI:MGI:5593382 +102637407 Gm34224 MGI:MGI:5593383 +102637409 LOC102637409 - +102637410 Gm34225 MGI:MGI:5593384 +102637411 Gm38498 MGI:MGI:5621383 +102637413 Gm34226 MGI:MGI:5593385 +102637414 Gm34227 MGI:MGI:5593386 +102637416 Gm34229 MGI:MGI:5593388 +102637417 Gm7735 MGI:MGI:3649168|Ensembl:ENSMUSG00000068068 +102637419 LOC102637419 - +102637420 Gm34230 MGI:MGI:5593389 +102637421 Gm34231 MGI:MGI:5593390 +102637422 Gm34232 MGI:MGI:5593391 +102637423 Gm34233 MGI:MGI:5593392 +102637425 Gm34235 MGI:MGI:5593394 +102637427 Gm34237 MGI:MGI:5593396 +102637430 Gm34240 MGI:MGI:5593399|Ensembl:ENSMUSG00000104336 +102637431 Gm34241 MGI:MGI:5593400 +102637433 Gm21765 MGI:MGI:5433929 +102637435 Gm34243 MGI:MGI:5593402 +102637436 Gm26560 MGI:MGI:5477054 +102637437 Gm34244 MGI:MGI:5593403 +102637438 Gm34245 MGI:MGI:5593404 +102637439 Gm34246 MGI:MGI:5593405 +102637441 Gm34248 MGI:MGI:5593407 +102637442 Gm16208 MGI:MGI:3802096|Ensembl:ENSMUSG00000085464 +102637443 Gm34249 MGI:MGI:5593408 +102637444 Gm34250 MGI:MGI:5593409 +102637445 Gm34251 MGI:MGI:5593410 +102637446 Gm34252 MGI:MGI:5593411 +102637447 Gm34253 MGI:MGI:5593412 +102637448 Gm11732 MGI:MGI:3652087|Ensembl:ENSMUSG00000085336 +102637449 Gm34254 MGI:MGI:5593413 +102637450 Gm34255 MGI:MGI:5593414 +102637451 Gm16139 MGI:MGI:3801880 +102637452 Gm34256 MGI:MGI:5593415 +102637453 Gm34257 MGI:MGI:5593416 +102637454 Gm34258 MGI:MGI:5593417 +102637455 Gm16547 MGI:MGI:4414967 +102637456 Gm34259 MGI:MGI:5593418 +102637458 Gm34261 MGI:MGI:5593420 +102637459 Gm34262 MGI:MGI:5593421 +102637460 Gm34263 MGI:MGI:5593422 +102637461 Gm34264 MGI:MGI:5593423 +102637462 Gm34265 MGI:MGI:5593424 +102637463 Gm34266 MGI:MGI:5593425 +102637464 Gm34267 MGI:MGI:5593426 +102637465 Gm34268 MGI:MGI:5593427 +102637466 Gm34269 MGI:MGI:5593428 +102637467 Gm34270 MGI:MGI:5593429 +102637469 LOC102637469 - +102637470 Gm34272 MGI:MGI:5593431 +102637471 Gm34273 MGI:MGI:5593432 +102637472 Gm34274 MGI:MGI:5593433 +102637473 Gm21771 MGI:MGI:5433935 +102637474 Gm21745 MGI:MGI:5433909 +102637475 Gm29637 MGI:MGI:5580343 +102637476 Gm21757 MGI:MGI:5433921 +102637478 Gm34276 MGI:MGI:5593435 +102637479 Gm34277 MGI:MGI:5593436 +102637480 Zar1ps - +102637481 Gm34278 MGI:MGI:5593437 +102637483 LOC102637483 - +102637485 Gm34280 MGI:MGI:5593439 +102637486 Gm34281 MGI:MGI:5593440 +102637487 Gm34282 MGI:MGI:5593441 +102637489 Gm34283 MGI:MGI:5593442 +102637490 Gm34284 MGI:MGI:5593443 +102637491 LOC102637491 - +102637492 Gm34285 MGI:MGI:5593444 +102637493 Gm34286 MGI:MGI:5593445 +102637494 Gm34287 MGI:MGI:5593446 +102637495 LOC102637495 - +102637496 Gm34288 MGI:MGI:5593447 +102637497 Gm34289 MGI:MGI:5593448 +102637498 Gm34290 MGI:MGI:5593449 +102637499 Gm34291 MGI:MGI:5593450 +102637500 Gm34292 MGI:MGI:5593451 +102637501 Gm34293 MGI:MGI:5593452 +102637502 Gm34294 MGI:MGI:5593453 +102637503 Gm34295 MGI:MGI:5593454 +102637505 Gm34296 MGI:MGI:5593455 +102637506 Gm34297 MGI:MGI:5593456 +102637507 Gm34298 MGI:MGI:5593457 +102637508 Gm34299 MGI:MGI:5593458 +102637509 Gm34300 MGI:MGI:5593459 +102637510 Gm34301 MGI:MGI:5593460 +102637511 Gm34302 MGI:MGI:5593461|Ensembl:ENSMUSG00000103476|Vega:OTTMUSG00000051887 +102637513 Gm34303 MGI:MGI:5593462 +102637514 Gm34304 MGI:MGI:5593463|Ensembl:ENSMUSG00000112763 +102637515 LOC102637515 - +102637516 Gm29413 MGI:MGI:5580119 +102637517 Gm34305 MGI:MGI:5593464 +102637518 Gm28284 MGI:MGI:5578990|Ensembl:ENSMUSG00000101317 +102637519 Gm34306 MGI:MGI:5593465 +102637520 Gm34307 MGI:MGI:5593466 +102637521 Gm15736 MGI:MGI:3783178 +102637525 Gm34311 MGI:MGI:5593470 +102637526 Gm34312 MGI:MGI:5593471 +102637527 Gm34313 MGI:MGI:5593472 +102637528 Gm34314 MGI:MGI:5593473 +102637529 Gm34315 MGI:MGI:5593474 +102637530 Gm34316 MGI:MGI:5593475 +102637531 Gm34317 MGI:MGI:5593476 +102637532 LOC102637532 - +102637534 Cpop - +102637535 Gm34319 MGI:MGI:5593478 +102637536 Gm34320 MGI:MGI:5593479 +102637537 Gm34321 MGI:MGI:5593480 +102637538 Gm34322 MGI:MGI:5593481|Ensembl:ENSMUSG00000111033 +102637539 Gm28167 MGI:MGI:5578873 +102637540 Gm34323 MGI:MGI:5593482 +102637541 Gm34324 MGI:MGI:5593483 +102637542 LOC102637542 - +102637543 Gm34325 MGI:MGI:5593484 +102637544 Gm34326 MGI:MGI:5593485 +102637545 Gm34327 MGI:MGI:5593486 +102637546 Gm13025 MGI:MGI:3650883 +102637547 Gm34328 MGI:MGI:5593487|Ensembl:ENSMUSG00000112028 +102637548 Gm17521 MGI:MGI:4937155 +102637549 Gm29286 MGI:MGI:5579992|Ensembl:ENSMUSG00000099977 +102637550 Gm28786 MGI:MGI:5579492 +102637552 Gm34330 MGI:MGI:5593489 +102637553 Gm34331 MGI:MGI:5593490 +102637554 Gm34332 MGI:MGI:5593491 +102637555 Gm34333 MGI:MGI:5593492|Ensembl:ENSMUSG00000105907 +102637556 Gm34334 MGI:MGI:5593493 +102637557 Gm34335 MGI:MGI:5593494 +102637558 Gm34336 MGI:MGI:5593495 +102637559 Gm28114 MGI:MGI:5578820 +102637560 Gm34337 MGI:MGI:5593496 +102637561 Gm34338 MGI:MGI:5593497 +102637563 Gm34340 MGI:MGI:5593499 +102637565 Gm34342 MGI:MGI:5593501 +102637566 LOC102637566 - +102637567 Gm34343 MGI:MGI:5593502 +102637568 Gm34344 MGI:MGI:5593503 +102637569 Gm34345 MGI:MGI:5593504 +102637570 Gm34346 MGI:MGI:5593505 +102637571 Gm34347 MGI:MGI:5593506 +102637572 Gm38499 MGI:MGI:5621384 +102637573 Gm34348 MGI:MGI:5593507 +102637574 Gm34349 MGI:MGI:5593508 +102637575 Gm34350 MGI:MGI:5593509 +102637576 Gm15283 MGI:MGI:3705161 +102637577 LOC102637577 - +102637578 LOC102637578 - +102637580 Gm29634 MGI:MGI:5580340 +102637581 Gm34352 MGI:MGI:5593511 +102637582 Gm34353 MGI:MGI:5593512 +102637583 Gm34354 MGI:MGI:5593513 +102637585 Gm34356 MGI:MGI:5593515 +102637586 Gm34357 MGI:MGI:5593516 +102637587 Gm34358 MGI:MGI:5593517|Ensembl:ENSMUSG00000108285 +102637589 Gm15870 MGI:MGI:3802066 +102637590 Gm34360 MGI:MGI:5593519 +102637592 Gm34361 MGI:MGI:5593520 +102637593 Gm34362 MGI:MGI:5593521 +102637594 Gm34363 MGI:MGI:5593522 +102637595 Gm34364 MGI:MGI:5593523 +102637596 Platr13 MGI:MGI:3651752 +102637598 Gm34365 MGI:MGI:5593524 +102637599 Gm34366 MGI:MGI:5593525 +102637600 Gm34367 MGI:MGI:5593526 +102637601 Gm34368 MGI:MGI:5593527 +102637602 Gm34369 MGI:MGI:5593528 +102637603 Gm34370 MGI:MGI:5593529 +102637604 Gm34371 MGI:MGI:5593530 +102637605 Gm15425 MGI:MGI:3705642 +102637607 Gm34372 MGI:MGI:5593531 +102637609 Gm34374 MGI:MGI:5593533 +102637611 Gm34375 MGI:MGI:5593534 +102637612 Gm34376 MGI:MGI:5593535 +102637613 Gm12092 MGI:MGI:3650092 +102637615 LOC102637615 Ensembl:ENSMUSG00000099898|Vega:OTTMUSG00000045791 +102637617 Gm34379 MGI:MGI:5593538 +102637619 Gm34381 MGI:MGI:5593540 +102637620 Gm34382 MGI:MGI:5593541 +102637623 Gm34385 MGI:MGI:5593544 +102637626 Gm34388 MGI:MGI:5593547 +102637627 Gm34389 MGI:MGI:5593548 +102637629 Gm34391 MGI:MGI:5593550 +102637630 Gm34392 MGI:MGI:5593551 +102637631 Gm34393 MGI:MGI:5593552 +102637632 Gm34394 MGI:MGI:5593553 +102637633 Gm34395 MGI:MGI:5593554 +102637634 Gm34396 MGI:MGI:5593555 +102637635 Gm34397 MGI:MGI:5593556 +102637637 LOC102637637 - +102637640 Gm12506 MGI:MGI:3651170 +102637641 Gm34401 MGI:MGI:5593560 +102637642 Gm34402 MGI:MGI:5593561 +102637643 Gm34403 MGI:MGI:5593562 +102637645 Gm34405 MGI:MGI:5593564 +102637646 LOC102637646 - +102637647 Gm34406 MGI:MGI:5593565 +102637648 Gm34407 MGI:MGI:5593566 +102637649 Gm34408 MGI:MGI:5593567 +102637650 Gm17412 MGI:MGI:4937046 +102637651 Gm28753 MGI:MGI:5579459 +102637652 Gm28596 MGI:MGI:5579302 +102637653 Gm28106 MGI:MGI:5578812 +102637654 Gm34409 MGI:MGI:5593568 +102637656 Gm34411 MGI:MGI:5593570 +102637657 Gm29346 MGI:MGI:5580052 +102637658 Gm34412 MGI:MGI:5593571 +102637659 Gm34413 MGI:MGI:5593572 +102637660 Gm34414 MGI:MGI:5593573 +102637661 Gm34415 MGI:MGI:5593574 +102637662 Gm34416 MGI:MGI:5593575 +102637663 Gm34417 MGI:MGI:5593576 +102637664 Gm34418 MGI:MGI:5593577 +102637665 Gm34419 MGI:MGI:5593578 +102637666 Gm34420 MGI:MGI:5593579 +102637668 Gm34421 MGI:MGI:5593580 +102637670 Gm34423 MGI:MGI:5593582 +102637671 Gm13198 MGI:MGI:3651172 +102637672 Gm26787 MGI:MGI:5477281 +102637673 Gm34424 MGI:MGI:5593583|Ensembl:ENSMUSG00000111381 +102637674 Gm34425 MGI:MGI:5593584 +102637675 Gm34426 MGI:MGI:5593585 +102637677 Gm34428 MGI:MGI:5593587 +102637678 Gm12403 MGI:MGI:3650109 +102637679 Gm13575 MGI:MGI:3651703 +102637681 Gm34430 MGI:MGI:5593589 +102637682 Gm26682 MGI:MGI:5477176 +102637683 Gm34431 MGI:MGI:5593590 +102637684 Gm20609 MGI:MGI:5313056|Ensembl:ENSMUSG00000093732 +102637685 Gm16239 MGI:MGI:3801746 +102637686 Gm34432 MGI:MGI:5593591 +102637687 Gm34433 MGI:MGI:5593592 +102637688 Gm34434 MGI:MGI:5593593 +102637693 Gm26512 MGI:MGI:5477006 +102637694 Gm29659 MGI:MGI:5580365 +102637696 Gm34439 MGI:MGI:5593598 +102637697 Gm34440 MGI:MGI:5593599 +102637698 Gm34441 MGI:MGI:5593600 +102637699 Gm34442 MGI:MGI:5593601 +102637701 Gm34444 MGI:MGI:5593603 +102637702 Gm16342 MGI:MGI:3840138 +102637703 Gm34445 MGI:MGI:5593604 +102637704 Gm34446 MGI:MGI:5593605 +102637705 Ly6l MGI:MGI:5313101|Ensembl:ENSMUSG00000093626|Vega:OTTMUSG00000042113 +102637706 Gm34447 MGI:MGI:5593606 +102637707 Gm34448 MGI:MGI:5593607 +102637708 Gm34449 MGI:MGI:5593608 +102637709 Gm34450 MGI:MGI:5593609 +102637710 Gm34451 MGI:MGI:5593610 +102637711 LOC102637711 - +102637713 Gm34453 MGI:MGI:5593612 +102637714 Gm34454 MGI:MGI:5593613 +102637715 Gm34455 MGI:MGI:5593614 +102637717 Gm34457 MGI:MGI:5593616 +102637718 Gm34458 MGI:MGI:5593617 +102637719 Gm38500 MGI:MGI:5621385 +102637720 LOC102637720 Ensembl:ENSMUSG00000090235 +102637721 Gm34459 MGI:MGI:5593618 +102637723 Gm34461 MGI:MGI:5593620 +102637724 Gm34462 MGI:MGI:5593621 +102637725 Gm34463 MGI:MGI:5593622 +102637726 Gm34464 MGI:MGI:5593623 +102637728 Gm34465 MGI:MGI:5593624 +102637729 Gm28355 MGI:MGI:5579061 +102637730 Gm34466 MGI:MGI:5593625|Ensembl:ENSMUSG00000113919 +102637731 Gm34467 MGI:MGI:5593626 +102637732 Gm34468 MGI:MGI:5593627 +102637733 Gm34469 MGI:MGI:5593628 +102637734 Gm34470 MGI:MGI:5593629 +102637735 Gm34471 MGI:MGI:5593630 +102637737 LOC102637737 - +102637738 Gm34472 MGI:MGI:5593631 +102637740 Gm34474 MGI:MGI:5593633|Ensembl:ENSMUSG00000109773 +102637741 Gm34475 MGI:MGI:5593634 +102637742 LOC102637742 - +102637743 LOC102637743 - +102637744 Gm34476 MGI:MGI:5593635 +102637745 Gm34477 MGI:MGI:5593636 +102637746 Gm34478 MGI:MGI:5593637 +102637747 Gm34479 MGI:MGI:5593638 +102637748 Gm34480 MGI:MGI:5593639 +102637749 LOC102637749 - +102637750 Gm34481 MGI:MGI:5593640 +102637751 Gm34482 MGI:MGI:5593641 +102637752 Gm34483 MGI:MGI:5593642 +102637753 Gm34484 MGI:MGI:5593643 +102637756 Gm34486 MGI:MGI:5593645 +102637758 Gm34488 MGI:MGI:5593647 +102637759 Gm34489 MGI:MGI:5593648 +102637760 Gm34490 MGI:MGI:5593649 +102637761 Gm34491 MGI:MGI:5593650 +102637762 Gm21812 MGI:MGI:5433976 +102637763 LOC102637763 - +102637765 Gm34493 MGI:MGI:5593652 +102637768 Gm28107 MGI:MGI:5578813 +102637769 Gm34496 MGI:MGI:5593655 +102637770 Gm34497 MGI:MGI:5593656 +102637772 Gm34499 MGI:MGI:5593658 +102637773 Gm34500 MGI:MGI:5593659 +102637774 Gm34501 MGI:MGI:5593660 +102637775 Gm38501 MGI:MGI:5621386 +102637776 Gm34502 MGI:MGI:5593661 +102637777 Gm34503 MGI:MGI:5593662 +102637778 Gm34504 MGI:MGI:5593663 +102637779 Gm34505 MGI:MGI:5593664 +102637781 LOC102637781 - +102637782 Gm34507 MGI:MGI:5593666 +102637784 Gm34509 MGI:MGI:5593668 +102637785 Gm34510 MGI:MGI:5593669 +102637786 Gm34511 MGI:MGI:5593670 +102637787 Gm26740 MGI:MGI:5477234 +102637788 Gm12405 MGI:MGI:3649392 +102637790 Gm34513 MGI:MGI:5593672 +102637791 Gm34514 MGI:MGI:5593673 +102637792 LOC102637792 - +102637793 Gm34515 MGI:MGI:5593674 +102637794 Gm34516 MGI:MGI:5593675 +102637795 Gm34517 MGI:MGI:5593676 +102637797 A330015K06Rik MGI:MGI:2443553|Ensembl:ENSMUSG00000104093 +102637800 Gm34521 MGI:MGI:5593680 +102637801 Gm34522 MGI:MGI:5593681 +102637802 Gm34523 MGI:MGI:5593682 +102637803 Gm29581 MGI:MGI:5580287 +102637806 LOC102637806 - +102637807 Gm34526 MGI:MGI:5593685 +102637808 LOC102637808 Ensembl:ENSMUSG00000096330|Vega:OTTMUSG00000042307 +102637809 Gm34527 MGI:MGI:5593686 +102637810 Gm34528 MGI:MGI:5593687 +102637812 Gm17027 MGI:MGI:4937854 +102637813 Gm34529 MGI:MGI:5593688 +102637814 LOC102637814 Ensembl:ENSMUSG00000087306 +102637815 LOC102637815 - +102637816 Gm34530 MGI:MGI:5593689 +102637817 Gm34531 MGI:MGI:5593690 +102637819 Gm34533 MGI:MGI:5593692|Ensembl:ENSMUSG00000109607 +102637820 Hopxos MGI:MGI:3801917 +102637821 Gm34534 MGI:MGI:5593693 +102637822 Gm34535 MGI:MGI:5593694 +102637823 Gm34536 MGI:MGI:5593695 +102637825 Gm34538 MGI:MGI:5593697 +102637827 Gm38502 MGI:MGI:5621387 +102637828 Gm12519 MGI:MGI:3652272 +102637829 Gm34539 MGI:MGI:5593698 +102637830 Gm34540 MGI:MGI:5593699 +102637831 Gm34541 MGI:MGI:5593700 +102637832 Gm34542 MGI:MGI:5593701 +102637834 Gm34544 MGI:MGI:5593703 +102637835 Gm34545 MGI:MGI:5593704 +102637838 LOC102637838 - +102637839 Gm10476 MGI:MGI:3779114 +102637841 Gm34548 MGI:MGI:5593707 +102637842 Gm34549 MGI:MGI:5593708 +102637843 Gm34550 MGI:MGI:5593709 +102637845 Gm34552 MGI:MGI:5593711 +102637848 Gm34554 MGI:MGI:5593713 +102637850 Gm34556 MGI:MGI:5593715 +102637851 Gm34557 MGI:MGI:5593716 +102637852 Gm34558 MGI:MGI:5593717 +102637854 LOC102637854 - +102637855 Gm34560 MGI:MGI:5593719 +102637856 Gm34561 MGI:MGI:5593720 +102637857 Gm34562 MGI:MGI:5593721 +102637858 Gm34563 MGI:MGI:5593722 +102637859 Gm20629 MGI:MGI:5313076 +102637862 Gm34566 MGI:MGI:5593725 +102637863 LOC102637863 - +102637864 Gm23428 MGI:MGI:5453205 +102637865 Gm34567 MGI:MGI:5593726 +102637866 Gm34568 MGI:MGI:5593727 +102637867 Gm34569 MGI:MGI:5593728 +102637868 Gm34570 MGI:MGI:5593729 +102637869 Gm34571 MGI:MGI:5593730 +102637870 Gm34572 MGI:MGI:5593731 +102637873 LOC102637873 - +102637874 Gm34574 MGI:MGI:5593733 +102637875 Gm34575 MGI:MGI:5593734 +102637876 Gm34576 MGI:MGI:5593735 +102637877 Gm34577 MGI:MGI:5593736 +102637878 LOC102637878 - +102637881 Gm34580 MGI:MGI:5593739 +102637882 LOC102637882 - +102637883 Gm29475 MGI:MGI:5580181 +102637884 Gm34581 MGI:MGI:5593740 +102637885 Gm28886 MGI:MGI:5579592 +102637886 Gm34582 MGI:MGI:5593741 +102637887 Gm34583 MGI:MGI:5593742 +102637888 Gm34584 MGI:MGI:5593743 +102637889 Gm34585 MGI:MGI:5593744 +102637890 Gm34586 MGI:MGI:5593745 +102637891 Gm34587 MGI:MGI:5593746 +102637892 Gm34588 MGI:MGI:5593747 +102637893 Gm34589 MGI:MGI:5593748 +102637894 Gm34590 MGI:MGI:5593749 +102637895 Gm34591 MGI:MGI:5593750 +102637896 Gm34592 MGI:MGI:5593751 +102637897 Gm34593 MGI:MGI:5593752 +102637898 Gm34594 MGI:MGI:5593753 +102637899 Gm34595 MGI:MGI:5593754 +102637900 Gm34596 MGI:MGI:5593755 +102637901 Gm34597 MGI:MGI:5593756 +102637902 Gm34598 MGI:MGI:5593757 +102637903 Gm34599 MGI:MGI:5593758 +102637904 Gm34600 MGI:MGI:5593759 +102637905 Gm34601 MGI:MGI:5593760 +102637906 Gm34602 MGI:MGI:5593761 +102637909 Gm34604 MGI:MGI:5593763 +102637910 Gm34605 MGI:MGI:5593764 +102637911 Gm34606 MGI:MGI:5593765 +102637912 LOC102637912 - +102637913 Gm34607 MGI:MGI:5593766 +102637914 Gm34608 MGI:MGI:5593767 +102637915 Gm13076 MGI:MGI:3651957 +102637916 Gm34609 MGI:MGI:5593768 +102637917 Gm34610 MGI:MGI:5593769 +102637919 Gm34611 MGI:MGI:5593770 +102637920 Gm34612 MGI:MGI:5593771 +102637921 LOC102637921 - +102637922 Gm34613 MGI:MGI:5593772 +102637925 Gm34616 MGI:MGI:5593775 +102637926 Gm16108 MGI:MGI:3802072 +102637928 Gm34617 MGI:MGI:5593776 +102637929 Gm34618 MGI:MGI:5593777 +102637930 Gm34619 MGI:MGI:5593778 +102637931 Gm34620 MGI:MGI:5593779 +102637932 Gm34621 MGI:MGI:5593780 +102637933 Gm34622 MGI:MGI:5593781 +102637934 Gm34623 MGI:MGI:5593782|Ensembl:ENSMUSG00000109966 +102637935 Gm34624 MGI:MGI:5593783 +102637936 Gm34625 MGI:MGI:5593784 +102637938 Gm34626 MGI:MGI:5593785 +102637939 Gm34627 MGI:MGI:5593786 +102637940 Gm34628 MGI:MGI:5593787 +102637941 Gm12602 MGI:MGI:3651757 +102637942 LOC102637942 - +102637943 Gm34629 MGI:MGI:5593788 +102637944 Gm34630 MGI:MGI:5593789 +102637946 Gm34632 MGI:MGI:5593791 +102637947 LOC102637947 - +102637948 Gm34633 MGI:MGI:5593792 +102637950 Gm34635 MGI:MGI:5593794 +102637951 Gm34636 MGI:MGI:5593795 +102637952 Gm34637 MGI:MGI:5593796 +102637953 Gm38503 MGI:MGI:5621388 +102637954 Gm34638 MGI:MGI:5593797 +102637955 Gm29531 MGI:MGI:5580237 +102637956 Gm34639 MGI:MGI:5593798|Ensembl:ENSMUSG00000113352 +102637957 Gm34640 MGI:MGI:5593799 +102637958 Gm34641 MGI:MGI:5593800 +102637959 Gm38504 MGI:MGI:5621389 +102637960 Gm34642 MGI:MGI:5593801 +102637961 Gm34643 MGI:MGI:5593802 +102637962 Gm34644 MGI:MGI:5593803 +102637963 Gm12622 MGI:MGI:3649877 +102637964 Gm34645 MGI:MGI:5593804 +102637965 Gm34646 MGI:MGI:5593805 +102637966 LOC102637966 - +102637967 Gm34647 MGI:MGI:5593806 +102637968 Gm34648 MGI:MGI:5593807 +102637969 Gm34649 MGI:MGI:5593808 +102637970 Gm34650 MGI:MGI:5593809 +102637971 Gm34651 MGI:MGI:5593810 +102637972 Gm34652 MGI:MGI:5593811 +102637973 Gm34653 MGI:MGI:5593812|Ensembl:ENSMUSG00000107167|Vega:OTTMUSG00000055609 +102637974 Gm34654 MGI:MGI:5593813 +102637975 Gm34655 MGI:MGI:5593814|Ensembl:ENSMUSG00000110863 +102637976 Gm34656 MGI:MGI:5593815 +102637977 Gm12404 MGI:MGI:3649601 +102637978 Gm34657 MGI:MGI:5593816 +102637979 Gm34658 MGI:MGI:5593817 +102637980 Gm34659 MGI:MGI:5593818 +102637981 Gm11954 MGI:MGI:3649565 +102637983 Gm34661 MGI:MGI:5593820 +102637984 Gm34662 MGI:MGI:5593821|Ensembl:ENSMUSG00000113092 +102637985 LOC102637985 - +102637987 Gm34664 MGI:MGI:5593823|Ensembl:ENSMUSG00000109407 +102637988 Astx1a MGI:MGI:3705265 +102637989 Gm34665 MGI:MGI:5593824 +102637990 Gm34666 MGI:MGI:5593825 +102637991 Gm34667 MGI:MGI:5593826 +102637993 Gm34669 MGI:MGI:5593828 +102637995 Gm34671 MGI:MGI:5593830 +102637996 Gm21733 MGI:MGI:5433897 +102637997 Gm34672 MGI:MGI:5593831 +102637999 Gm34674 MGI:MGI:5593833 +102638000 Gm34675 MGI:MGI:5593834 +102638001 Gm34676 MGI:MGI:5593835 +102638002 LOC102638002 - +102638003 LOC102638003 - +102638004 Gm34677 MGI:MGI:5593836 +102638005 Gm11734 MGI:MGI:3652086 +102638006 Gm14372 MGI:MGI:3649263 +102638007 Gm34678 MGI:MGI:5593837 +102638008 Gm38505 MGI:MGI:5621390 +102638009 Gm34679 MGI:MGI:5593838 +102638010 Gm34680 MGI:MGI:5593839 +102638013 Gm34682 MGI:MGI:5593841 +102638015 Gm34684 MGI:MGI:5593843 +102638016 Gm17382 MGI:MGI:4937016 +102638018 Gm34686 MGI:MGI:5593845 +102638019 Gm34687 MGI:MGI:5593846 +102638020 Gm34688 MGI:MGI:5593847 +102638021 Gm34689 MGI:MGI:5593848 +102638022 Gm34690 MGI:MGI:5593849 +102638025 Gm34693 MGI:MGI:5593852 +102638027 Gm34695 MGI:MGI:5593854 +102638028 Gm20467 MGI:MGI:5141932|Ensembl:ENSMUSG00000092250 +102638029 Gm34696 MGI:MGI:5593855 +102638030 Gm21907 MGI:MGI:5434071 +102638031 Gm34697 MGI:MGI:5593856 +102638032 Gm28471 MGI:MGI:5579177 +102638033 Gm34698 MGI:MGI:5593857 +102638034 Gm34699 MGI:MGI:5593858 +102638035 Gm34700 MGI:MGI:5593859 +102638036 Gm34701 MGI:MGI:5593860 +102638037 Gm34702 MGI:MGI:5593861 +102638038 Gm15631 MGI:MGI:3783075 +102638039 Gm34703 MGI:MGI:5593862 +102638040 Gm15515 MGI:MGI:3782962 +102638041 Gm12146 MGI:MGI:3649687 +102638042 Gm34704 MGI:MGI:5593863 +102638044 Gm34705 MGI:MGI:5593864 +102638046 Gm34707 MGI:MGI:5593866 +102638047 LOC102638047 Ensembl:ENSMUSG00000079808 +102638051 Gm13657 MGI:MGI:3650031 +102638052 Gm13869 MGI:MGI:3650539|Ensembl:ENSMUSG00000086957 +102638057 Gm34712 MGI:MGI:5593871 +102638058 Gm26976 MGI:MGI:5504091 +102638059 Gm34713 MGI:MGI:5593872 +102638061 Gm34714 MGI:MGI:5593873 +102638062 Gm34715 MGI:MGI:5593874 +102638063 Gm34716 MGI:MGI:5593875 +102638064 Gm34717 MGI:MGI:5593876 +102638065 Gm34718 MGI:MGI:5593877 +102638066 Gm34719 MGI:MGI:5593878 +102638067 Gm29426 MGI:MGI:5580132|Ensembl:ENSMUSG00000102031 +102638068 Gm28899 MGI:MGI:5579605 +102638069 Gm34720 MGI:MGI:5593879 +102638070 Gm16304 MGI:MGI:3826518 +102638071 Gm34721 MGI:MGI:5593880 +102638072 Gm34722 MGI:MGI:5593881 +102638073 Gm34723 MGI:MGI:5593882 +102638074 Gm34724 MGI:MGI:5593883 +102638075 Gm12628 MGI:MGI:3650568 +102638076 Gm34725 MGI:MGI:5593884 +102638077 Gm34726 MGI:MGI:5593885 +102638078 Gm34727 MGI:MGI:5593886 +102638079 Gm34728 MGI:MGI:5593887 +102638080 Gm16226 MGI:MGI:3801792 +102638082 Gm34730 MGI:MGI:5593889 +102638083 Ccdc188 - +102638085 LOC102638085 - +102638086 Gm34732 MGI:MGI:5593891|Ensembl:ENSMUSG00000103942 +102638087 Gm34733 MGI:MGI:5593892 +102638089 LOC102638089 - +102638090 Gm34735 MGI:MGI:5593894 +102638091 Gm34736 MGI:MGI:5593895 +102638093 Gm34738 MGI:MGI:5593897 +102638094 Gm34739 MGI:MGI:5593898 +102638095 Gm34740 MGI:MGI:5593899 +102638096 Gm34741 MGI:MGI:5593900 +102638097 Gm16344 MGI:MGI:3840129 +102638098 Gm34743 MGI:MGI:5593902 +102638099 Gm34744 MGI:MGI:5593903 +102638101 Gm28510 MGI:MGI:5579216 +102638102 Gm34745 MGI:MGI:5593904 +102638103 Gm20922 MGI:MGI:5434278 +102638104 Gm34746 MGI:MGI:5593905 +102638105 Gm29268 MGI:MGI:5579974 +102638106 Gm34747 MGI:MGI:5593906 +102638109 Gm34749 MGI:MGI:5593908 +102638110 LOC102638110 - +102638112 Gm34751 MGI:MGI:5593910 +102638113 Gm34752 MGI:MGI:5593911 +102638114 Gm34753 MGI:MGI:5593912 +102638115 Gm34754 MGI:MGI:5593913 +102638116 LOC102638116 - +102638117 Gm34755 MGI:MGI:5593914 +102638118 Gm34756 MGI:MGI:5593915 +102638119 Gm34757 MGI:MGI:5593916 +102638120 Gm34758 MGI:MGI:5593917 +102638121 Gm34759 MGI:MGI:5593918 +102638122 Gm34760 MGI:MGI:5593919 +102638124 Gm34762 MGI:MGI:5593921 +102638125 Gm20511 MGI:MGI:5141976 +102638127 Gm34764 MGI:MGI:5593923 +102638128 Gm34765 MGI:MGI:5593924 +102638129 Gm11587 MGI:MGI:3652110 +102638130 Gm34766 MGI:MGI:5593925 +102638131 Gm34767 MGI:MGI:5593926 +102638132 Gm34768 MGI:MGI:5593927 +102638133 Gm34769 MGI:MGI:5593928 +102638134 Gm34770 MGI:MGI:5593929 +102638135 Gm34771 MGI:MGI:5593930 +102638136 Gm34772 MGI:MGI:5593931 +102638137 Gm34773 MGI:MGI:5593932 +102638138 Gm26585 MGI:MGI:5477079 +102638141 Gm34776 MGI:MGI:5593935 +102638142 Gm34777 MGI:MGI:5593936 +102638145 Gm34779 MGI:MGI:5593938 +102638146 Gm34780 MGI:MGI:5593939 +102638147 Gm34781 MGI:MGI:5593940 +102638148 Gm34782 MGI:MGI:5593941 +102638149 Gm34783 MGI:MGI:5593942 +102638150 LOC102638150 - +102638151 Gm16876 MGI:MGI:4439800 +102638152 Gm34784 MGI:MGI:5593943 +102638153 Gm34785 MGI:MGI:5593944|Ensembl:ENSMUSG00000113733 +102638154 Gm21856 MGI:MGI:5434020 +102638155 Gm34786 MGI:MGI:5593945 +102638158 Gm34788 MGI:MGI:5593947 +102638159 Gm13790 MGI:MGI:3650747 +102638160 Gm34789 MGI:MGI:5593948 +102638161 Gm34790 MGI:MGI:5593949 +102638163 Gm34792 MGI:MGI:5593951 +102638164 Gm34793 MGI:MGI:5593952 +102638165 Gm11494 MGI:MGI:3649754|Ensembl:ENSMUSG00000085074 +102638166 Gm34794 MGI:MGI:5593953 +102638167 Gm38506 MGI:MGI:5621391 +102638168 Gm34795 MGI:MGI:5593954 +102638170 Gm34797 MGI:MGI:5593956 +102638171 Gm34798 MGI:MGI:5593957 +102638172 Gm34799 MGI:MGI:5593958 +102638174 Gm34801 MGI:MGI:5593960 +102638175 Gm11816 MGI:MGI:3650294 +102638176 Gm34802 MGI:MGI:5593961 +102638178 Gm34804 MGI:MGI:5593963 +102638179 Gm34805 MGI:MGI:5593964 +102638180 Gm34806 MGI:MGI:5593965 +102638181 Gm11447 MGI:MGI:3651506 +102638182 Gm34807 MGI:MGI:5593966 +102638183 LOC102638183 - +102638184 LOC102638184 - +102638185 Gm34808 MGI:MGI:5593967 +102638186 Gm20486 MGI:MGI:5141951 +102638187 Gm34809 MGI:MGI:5593968|Ensembl:ENSMUSG00000113272 +102638188 Gm34810 MGI:MGI:5593969 +102638189 Gm34811 MGI:MGI:5593970 +102638190 LOC102638190 - +102638192 Gm34812 MGI:MGI:5593971 +102638195 LOC102638195 - +102638196 Gm34815 MGI:MGI:5593974 +102638197 Gm34816 MGI:MGI:5593975|Ensembl:ENSMUSG00000102661 +102638199 LOC102638199 - +102638200 Gm34818 MGI:MGI:5593977 +102638201 E130120K24Rik MGI:MGI:1925806 +102638202 Gm34819 MGI:MGI:5593978 +102638203 Gm34820 MGI:MGI:5593979 +102638204 Gm34821 MGI:MGI:5593980 +102638205 Gm34822 MGI:MGI:5593981 +102638206 Gm12621 MGI:MGI:3649876 +102638207 Gm34823 MGI:MGI:5593982 +102638208 Gm15569 MGI:MGI:3826526|Ensembl:ENSMUSG00000086424 +102638209 Gm16152 MGI:MGI:3802058 +102638210 Gm34824 MGI:MGI:5593983 +102638211 Gm34825 MGI:MGI:5593984 +102638212 Gm9929 MGI:MGI:3708526 +102638213 Gm34826 MGI:MGI:5593985 +102638215 Gm34828 MGI:MGI:5593987 +102638216 Gm34829 MGI:MGI:5593988 +102638218 Gm34831 MGI:MGI:5593990 +102638219 Gm34832 MGI:MGI:5593991 +102638220 Gm34833 MGI:MGI:5593992 +102638221 Gm14637 MGI:MGI:3705296 +102638222 Gm34834 MGI:MGI:5593993 +102638224 Gm34836 MGI:MGI:5593995 +102638225 Gm34837 MGI:MGI:5593996 +102638226 Gm14769 MGI:MGI:3708088 +102638227 Gm34838 MGI:MGI:5593997 +102638228 Gm29525 MGI:MGI:5580231 +102638230 Gm21908 MGI:MGI:5434072 +102638232 Gm34841 MGI:MGI:5594000 +102638234 Gm34843 MGI:MGI:5594002 +102638235 Gm34844 MGI:MGI:5594003 +102638236 Gm34845 MGI:MGI:5594004 +102638237 Gm34846 MGI:MGI:5594005 +102638238 Gm34847 MGI:MGI:5594006 +102638239 Gm34848 MGI:MGI:5594007 +102638240 Gm34849 MGI:MGI:5594008 +102638241 Gm34850 MGI:MGI:5594009 +102638242 Gm34851 MGI:MGI:5594010 +102638243 Gm34852 MGI:MGI:5594011 +102638244 Gm34853 MGI:MGI:5594012 +102638245 Gm34854 MGI:MGI:5594013 +102638247 Gm34856 MGI:MGI:5594015 +102638248 Gm34857 MGI:MGI:5594016 +102638249 Gm34858 MGI:MGI:5594017 +102638251 Gm12536 MGI:MGI:3650719 +102638253 Gm34861 MGI:MGI:5594020 +102638254 LOC102638254 - +102638255 LOC102638255 - +102638256 Gm34862 MGI:MGI:5594021 +102638257 Gm34863 MGI:MGI:5594022 +102638258 Gm12103 MGI:MGI:3651382 +102638259 Gm20616 MGI:MGI:5313063|Ensembl:ENSMUSG00000093628 +102638260 Gm34864 MGI:MGI:5594023 +102638261 Gm34865 MGI:MGI:5594024 +102638262 Gm34866 MGI:MGI:5594025 +102638263 LOC102638263 - +102638265 Gm34868 MGI:MGI:5594027 +102638266 Gm34869 MGI:MGI:5594028 +102638268 LOC102638268 Ensembl:ENSMUSG00000051054|Vega:OTTMUSG00000042351 +102638269 Gm34871 MGI:MGI:5594030 +102638270 Gm34872 MGI:MGI:5594031 +102638271 Gm34873 MGI:MGI:5594032 +102638272 Gm34874 MGI:MGI:5594033 +102638275 Gm34877 MGI:MGI:5594036 +102638276 LOC102638276 - +102638277 Gm34878 MGI:MGI:5594037 +102638278 Gm34879 MGI:MGI:5594038 +102638279 Gm34880 MGI:MGI:5594039 +102638280 Gm34881 MGI:MGI:5594040 +102638281 Gm34882 MGI:MGI:5594041|Ensembl:ENSMUSG00000103613 +102638282 Gm34883 MGI:MGI:5594042 +102638284 Gm34885 MGI:MGI:5594044 +102638285 Gm13415 MGI:MGI:3651241 +102638287 Gm34887 MGI:MGI:5594046 +102638288 Gm34888 MGI:MGI:5594047 +102638289 Gm34889 MGI:MGI:5594048 +102638290 Gm13171 MGI:MGI:3651089 +102638291 Gm34890 MGI:MGI:5594049 +102638292 Gm11959 MGI:MGI:3652300|Ensembl:ENSMUSG00000085559 +102638293 Gm34891 MGI:MGI:5594050 +102638295 Gm38507 MGI:MGI:5621392 +102638296 Gm17102 MGI:MGI:4937929|Ensembl:ENSMUSG00000091864 +102638298 Gm34894 MGI:MGI:5594053 +102638299 Gm34895 MGI:MGI:5594054 +102638301 Gm12841 MGI:MGI:3651048 +102638304 Gm34899 MGI:MGI:5594058 +102638305 Gm21722 MGI:MGI:5433886 +102638308 Gm34902 MGI:MGI:5594061 +102638309 Gm34903 MGI:MGI:5594062 +102638311 Gm34905 MGI:MGI:5594064 +102638313 Gm34907 MGI:MGI:5594066 +102638314 Gm12627 MGI:MGI:3650562 +102638315 Gm34908 MGI:MGI:5594067 +102638318 Gm16150 MGI:MGI:3801827 +102638319 Gm34911 MGI:MGI:5594070 +102638320 Gm34912 MGI:MGI:5594071 +102638321 Gm34913 MGI:MGI:5594072 +102638323 Gm34914 MGI:MGI:5594073 +102638324 Gm34915 MGI:MGI:5594074 +102638325 Gm34916 MGI:MGI:5594075 +102638326 Gm34917 MGI:MGI:5594076 +102638328 Gm34919 MGI:MGI:5594078 +102638330 Gm14264 MGI:MGI:3649394 +102638331 Gm34921 MGI:MGI:5594080 +102638332 Gm34922 MGI:MGI:5594081 +102638333 Gm34923 MGI:MGI:5594082 +102638334 Gm34924 MGI:MGI:5594083 +102638335 LOC102638335 - +102638336 Gm34925 MGI:MGI:5594084 +102638337 Gm34926 MGI:MGI:5594085 +102638338 Gm14901 MGI:MGI:3705592 +102638339 Gm34927 MGI:MGI:5594086 +102638341 Gm34929 MGI:MGI:5594088 +102638342 Gm34930 MGI:MGI:5594089 +102638343 Gm34931 MGI:MGI:5594090 +102638344 Gm38508 MGI:MGI:5621393 +102638346 Gm34933 MGI:MGI:5594092 +102638347 Gm34934 MGI:MGI:5594093 +102638348 Gm34935 MGI:MGI:5594094 +102638350 Gm16138 MGI:MGI:3801879 +102638351 Gm34937 MGI:MGI:5594096 +102638352 Gm34938 MGI:MGI:5594097 +102638353 Arhgap27os1 MGI:MGI:3705097 +102638354 Gm34939 MGI:MGI:5594098 +102638356 Gm34941 MGI:MGI:5594100 +102638357 Gm34942 MGI:MGI:5594101 +102638359 LOC102638359 - +102638361 LOC102638361 - +102638362 Gm34945 MGI:MGI:5594104 +102638363 Gm34946 MGI:MGI:5594105 +102638364 Gm34947 MGI:MGI:5594106 +102638365 Gm11869 MGI:MGI:3650284 +102638366 Gm34948 MGI:MGI:5594107 +102638367 Gm34949 MGI:MGI:5594108 +102638369 Gm34951 MGI:MGI:5594110 +102638370 Gm34952 MGI:MGI:5594111 +102638371 Gm11958 MGI:MGI:3652302 +102638376 Gm34957 MGI:MGI:5594116 +102638379 Gm29338 MGI:MGI:5580044|Ensembl:ENSMUSG00000101160 +102638380 Gm34960 MGI:MGI:5594119 +102638381 Gm34961 MGI:MGI:5594120 +102638382 Gm34962 MGI:MGI:5594121 +102638384 Gm34963 MGI:MGI:5594122 +102638385 Gm34964 MGI:MGI:5594123 +102638386 Gm34965 MGI:MGI:5594124 +102638387 Gm34966 MGI:MGI:5594125 +102638388 LOC102638388 - +102638389 LOC102638389 - +102638390 Gm34967 MGI:MGI:5594126 +102638391 Gm34968 MGI:MGI:5594127 +102638392 Gm34969 MGI:MGI:5594128 +102638393 Gm34970 MGI:MGI:5594129 +102638394 Gm34971 MGI:MGI:5594130 +102638395 Gm34972 MGI:MGI:5594131 +102638396 Gm34973 MGI:MGI:5594132 +102638397 Gm34974 MGI:MGI:5594133 +102638398 Gm34975 MGI:MGI:5594134 +102638401 Gm34978 MGI:MGI:5594137 +102638402 Gm34979 MGI:MGI:5594138 +102638403 Gm34980 MGI:MGI:5594139 +102638404 Gm34981 MGI:MGI:5594140 +102638405 Gm34982 MGI:MGI:5594141 +102638407 Gm34983 MGI:MGI:5594142 +102638408 Gm16174 MGI:MGI:3801857 +102638409 Gm34984 MGI:MGI:5594143 +102638410 Gm34985 MGI:MGI:5594144 +102638411 Gm34986 MGI:MGI:5594145 +102638412 LOC102638412 - +102638413 Gm34987 MGI:MGI:5594146 +102638414 Gm34988 MGI:MGI:5594147 +102638415 Gm28464 MGI:MGI:5579170 +102638416 Gm21877 MGI:MGI:5434041 +102638418 Gm21813 MGI:MGI:5433977 +102638420 Gm34991 MGI:MGI:5594150 +102638421 Gm34992 MGI:MGI:5594151 +102638422 Gm34993 MGI:MGI:5594152 +102638423 Gm34994 MGI:MGI:5594153 +102638424 Gm34995 MGI:MGI:5594154 +102638425 Gm34996 MGI:MGI:5594155 +102638426 Gm34997 MGI:MGI:5594156 +102638427 Gm34998 MGI:MGI:5594157 +102638428 Gm34999 MGI:MGI:5594158 +102638429 Gm12613 MGI:MGI:3649884 +102638430 Gm35000 MGI:MGI:5594159 +102638431 Gm35001 MGI:MGI:5594160 +102638432 Gm35002 MGI:MGI:5594161 +102638434 Gm16537 MGI:MGI:4414957 +102638435 LOC102638435 - +102638436 Gm38509 MGI:MGI:5621394|Ensembl:ENSMUSG00000106519 +102638437 Gm35004 MGI:MGI:5594163 +102638438 Gm35005 MGI:MGI:5594164 +102638440 Gm35006 MGI:MGI:5594165 +102638441 Gm35007 MGI:MGI:5594166 +102638442 LOC102638442 - +102638443 Gm35008 MGI:MGI:5594167 +102638445 Gm35010 MGI:MGI:5594169 +102638447 Gm35012 MGI:MGI:5594171 +102638448 LOC102638448 - +102638450 Gm35013 MGI:MGI:5594172 +102638451 Gm28657 MGI:MGI:5579363 +102638453 Gm21783 MGI:MGI:5433947 +102638454 LOC102638454 - +102638455 Gm35015 MGI:MGI:5594174 +102638457 Gm35017 MGI:MGI:5594176 +102638458 Gm35018 MGI:MGI:5594177 +102638459 Gm35019 MGI:MGI:5594178 +102638460 Gm12153 MGI:MGI:3649294|Ensembl:ENSMUSG00000087172 +102638461 Gm26793 MGI:MGI:5477287 +102638463 Gm35021 MGI:MGI:5594180 +102638464 Gm35022 MGI:MGI:5594181 +102638465 LOC102638465 - +102638466 LOC102638466 - +102638467 Gm35023 MGI:MGI:5594182 +102638468 Gm29050 MGI:MGI:5579756 +102638469 Gm35024 MGI:MGI:5594183|Ensembl:ENSMUSG00000111363 +102638470 Gm35025 MGI:MGI:5594184 +102638473 Gm35027 MGI:MGI:5594186 +102638474 Gm35028 MGI:MGI:5594187 +102638476 Gm35029 MGI:MGI:5594188 +102638477 Gm35030 MGI:MGI:5594189 +102638478 Gm35031 MGI:MGI:5594190 +102638479 Gm35032 MGI:MGI:5594191 +102638480 Gm35033 MGI:MGI:5594192 +102638481 Gm35034 MGI:MGI:5594193 +102638482 Gm35035 MGI:MGI:5594194 +102638484 Gm35037 MGI:MGI:5594196 +102638485 Tmem167-ps2 MGI:MGI:5580325 +102638487 Gm35039 MGI:MGI:5594198 +102638488 Gm35040 MGI:MGI:5594199 +102638490 Gm35041 MGI:MGI:5594200 +102638491 Gm35042 MGI:MGI:5594201 +102638492 Gm35043 MGI:MGI:5594202 +102638493 Gm35044 MGI:MGI:5594203 +102638496 Gm35047 MGI:MGI:5594206 +102638497 Gm35048 MGI:MGI:5594207 +102638498 Gm15732 MGI:MGI:3805556 +102638499 Gm35049 MGI:MGI:5594208 +102638501 Gm35051 MGI:MGI:5594210 +102638502 Gm10612 MGI:MGI:3708796 +102638504 Mipepos MGI:MGI:3801952 +102638505 Gm35053 MGI:MGI:5594212 +102638506 Gm35054 MGI:MGI:5594213 +102638507 Gm26684 MGI:MGI:5477178 +102638508 Gm17057 MGI:MGI:4937884 +102638509 Gm35055 MGI:MGI:5594214 +102638510 Gm35056 MGI:MGI:5594215 +102638512 Gm35058 MGI:MGI:5594217 +102638513 Gm35059 MGI:MGI:5594218 +102638514 Gm35060 MGI:MGI:5594219|Ensembl:ENSMUSG00000109238|Vega:OTTMUSG00000059513 +102638515 LOC102638515 - +102638516 Gm23711 MGI:MGI:5453488 +102638517 Gm35061 MGI:MGI:5594220 +102638518 Gm35062 MGI:MGI:5594221 +102638519 Gm35063 MGI:MGI:5594222 +102638520 Gm35064 MGI:MGI:5594223 +102638521 LOC102638521 - +102638522 Gm35065 MGI:MGI:5594224 +102638523 Gm35066 MGI:MGI:5594225 +102638524 Gm35067 MGI:MGI:5594226 +102638527 Gm35070 MGI:MGI:5594229 +102638528 Gm35071 MGI:MGI:5594230 +102638529 Gm28454 MGI:MGI:5579160 +102638531 Gm35073 MGI:MGI:5594232 +102638532 Gm21735 MGI:MGI:5433899 +102638533 Gm35074 MGI:MGI:5594233 +102638534 Gm28835 MGI:MGI:5579541 +102638536 Gm28716 MGI:MGI:5579422 +102638537 Hnf1aos1 MGI:MGI:3652225 +102638539 Gm35076 MGI:MGI:5594235 +102638540 Gm35077 MGI:MGI:5594236 +102638541 Gm35078 MGI:MGI:5594237 +102638542 Gm35079 MGI:MGI:5594238 +102638544 Gm35081 MGI:MGI:5594240 +102638545 Gm35082 MGI:MGI:5594241 +102638546 Gm35083 MGI:MGI:5594242 +102638547 Gm12614 MGI:MGI:3649885 +102638549 Gm35085 MGI:MGI:5594244 +102638551 Gm35087 MGI:MGI:5594246 +102638553 Gm16228 MGI:MGI:3801790 +102638554 Gm35089 MGI:MGI:5594248 +102638555 Gm38510 MGI:MGI:5621395 +102638556 Gm35090 MGI:MGI:5594249 +102638557 Gm35091 MGI:MGI:5594250 +102638559 Gm35093 MGI:MGI:5594252 +102638561 Gm35095 MGI:MGI:5594254 +102638563 Gm35097 MGI:MGI:5594256 +102638564 Gm35098 MGI:MGI:5594257 +102638565 Gm35099 MGI:MGI:5594258 +102638566 Gm35100 MGI:MGI:5594259 +102638567 Gm35101 MGI:MGI:5594260 +102638568 Gm35102 MGI:MGI:5594261 +102638569 Gm35103 MGI:MGI:5594262 +102638570 Gm35104 MGI:MGI:5594263 +102638571 Gm35105 MGI:MGI:5594264 +102638572 Gm35106 MGI:MGI:5594265 +102638573 Gm10477 MGI:MGI:3642464 +102638574 Gm35107 MGI:MGI:5594266 +102638575 Gm35108 MGI:MGI:5594267 +102638577 Gm29213 MGI:MGI:5579919 +102638578 Gm35109 MGI:MGI:5594268 +102638579 Gm28897 MGI:MGI:5579603 +102638580 Gm35110 MGI:MGI:5594269 +102638581 Gm35111 MGI:MGI:5594270 +102638582 Gm35112 MGI:MGI:5594271 +102638584 Gm35113 MGI:MGI:5594272 +102638585 Gm35114 MGI:MGI:5594273 +102638587 Gm35116 MGI:MGI:5594275 +102638588 Gm35117 MGI:MGI:5594276 +102638589 Gm35118 MGI:MGI:5594277 +102638592 Gm35120 MGI:MGI:5594279 +102638594 Gm35121 MGI:MGI:5594280 +102638595 Gm35122 MGI:MGI:5594281 +102638596 Gm35123 MGI:MGI:5594282 +102638598 Gm35125 MGI:MGI:5594284 +102638600 Gm35126 MGI:MGI:5594285 +102638602 Gm35128 MGI:MGI:5594287 +102638603 Gm35129 MGI:MGI:5594288 +102638604 Gm35130 MGI:MGI:5594289 +102638605 Gm35131 MGI:MGI:5594290 +102638606 Gm35132 MGI:MGI:5594291 +102638607 Gm15927 MGI:MGI:3801889 +102638608 Tmem167-ps3 MGI:MGI:5580326 +102638609 Gm35133 MGI:MGI:5594292 +102638610 Gm35134 MGI:MGI:5594293|Ensembl:ENSMUSG00000103371|Vega:OTTMUSG00000050367 +102638611 Gm35135 MGI:MGI:5594294|Ensembl:ENSMUSG00000111982 +102638612 Gm28879 MGI:MGI:5579585 +102638613 Gm35136 MGI:MGI:5594295 +102638614 Gm35137 MGI:MGI:5594296 +102638615 Gm35138 MGI:MGI:5594297 +102638616 Gm35139 MGI:MGI:5594298 +102638618 Gm35141 MGI:MGI:5594300 +102638620 Gm35143 MGI:MGI:5594302 +102638621 Gm35144 MGI:MGI:5594303 +102638622 Gm35145 MGI:MGI:5594304 +102638623 BB365896 MGI:MGI:3034340 +102638625 Gm35146 MGI:MGI:5594305 +102638626 Gm35147 MGI:MGI:5594306|Ensembl:ENSMUSG00000108849 +102638627 Gm35148 MGI:MGI:5594307 +102638628 Gm15580 MGI:MGI:3783028 +102638629 Gm35149 MGI:MGI:5594308 +102638630 Gm26779 MGI:MGI:5477273 +102638631 Gm35150 MGI:MGI:5594309 +102638632 Gm26641 MGI:MGI:5477135|Ensembl:ENSMUSG00000097045 +102638633 Gm26608 MGI:MGI:5477102 +102638634 Gm35151 MGI:MGI:5594310 +102638635 Gm35152 MGI:MGI:5594311 +102638637 Gm35154 MGI:MGI:5594313 +102638638 Gm14114 MGI:MGI:3652257 +102638639 Gm12774 MGI:MGI:3650283 +102638640 Gm35155 MGI:MGI:5594314 +102638641 Gm35156 MGI:MGI:5594315 +102638642 Gm28486 MGI:MGI:5579192|Ensembl:ENSMUSG00000099855 +102638644 Gm35158 MGI:MGI:5594317 +102638645 Gm35159 MGI:MGI:5594318 +102638646 Gm35160 MGI:MGI:5594319 +102638647 Gm35161 MGI:MGI:5594320 +102638648 Gm17450 MGI:MGI:4937084 +102638649 Gm35162 MGI:MGI:5594321 +102638650 Gm35163 MGI:MGI:5594322 +102638651 Gm35164 MGI:MGI:5594323 +102638652 Gm35165 MGI:MGI:5594324 +102638653 Gm35166 MGI:MGI:5594325 +102638654 Gm35167 MGI:MGI:5594326 +102638655 Gm20476 MGI:MGI:5141941 +102638656 Gm35168 MGI:MGI:5594327 +102638657 Gm12625 MGI:MGI:3650564 +102638658 Gm35169 MGI:MGI:5594328 +102638659 Gm35170 MGI:MGI:5594329 +102638660 Gm35171 MGI:MGI:5594330 +102638661 Gm35172 MGI:MGI:5594331 +102638662 LOC102638662 - +102638664 Gm35174 MGI:MGI:5594333 +102638666 Gm35176 MGI:MGI:5594335 +102638667 Gm35177 MGI:MGI:5594336 +102638668 Gm35178 MGI:MGI:5594337 +102638669 Gm35179 MGI:MGI:5594338 +102638670 LOC102638670 - +102638671 LOC102638671 - +102638672 Gm35180 MGI:MGI:5594339 +102638673 Gm35181 MGI:MGI:5594340 +102638674 LOC102638674 - +102638675 Gm35182 MGI:MGI:5594341 +102638676 Gm12107 MGI:MGI:3651177 +102638677 Gm35183 MGI:MGI:5594342 +102638678 Gm15959 MGI:MGI:3802064 +102638679 Gm35184 MGI:MGI:5594343 +102638680 Gm35185 MGI:MGI:5594344 +102638681 Gm35186 MGI:MGI:5594345 +102638682 Gm35187 MGI:MGI:5594346 +102638684 Gm28656 MGI:MGI:5579362 +102638685 Gm35188 MGI:MGI:5594347 +102638686 Gm35189 MGI:MGI:5594348 +102638687 Gm35190 MGI:MGI:5594349 +102638688 Gm28604 MGI:MGI:5579310 +102638689 Gm29115 MGI:MGI:5579821 +102638690 Gm35191 MGI:MGI:5594350|Ensembl:ENSMUSG00000107070 +102638691 Gm35192 MGI:MGI:5594351 +102638692 Gm35193 MGI:MGI:5594352 +102638693 Gm35194 MGI:MGI:5594353 +102638694 LOC102638694 - +102638695 Gm35195 MGI:MGI:5594354 +102638696 Gm26919 MGI:MGI:5504034 +102638697 Gm35196 MGI:MGI:5594355 +102638698 Gm35197 MGI:MGI:5594356 +102638699 Gm35198 MGI:MGI:5594357 +102638700 LOC102638700 - +102638701 Gm16350 MGI:MGI:3840133 +102638704 Gm35200 MGI:MGI:5594359 +102638705 Gm35201 MGI:MGI:5594360 +102638706 Gm35202 MGI:MGI:5594361 +102638707 Gm28996 MGI:MGI:5579702 +102638708 Gm35203 MGI:MGI:5594362 +102638709 Gm35204 MGI:MGI:5594363 +102638710 Gm26963 MGI:MGI:5504078 +102638712 Gm35206 MGI:MGI:5594365 +102638714 Gm35208 MGI:MGI:5594367 +102638715 Gm35209 MGI:MGI:5594368 +102638716 Gm35210 MGI:MGI:5594369 +102638718 Gm35212 MGI:MGI:5594371 +102638720 Gm35214 MGI:MGI:5594373 +102638721 Gm35215 MGI:MGI:5594374 +102638722 Gm35216 MGI:MGI:5594375|Ensembl:ENSMUSG00000107598 +102638723 Gm35217 MGI:MGI:5594376 +102638724 Gm35218 MGI:MGI:5594377 +102638725 Gm35219 MGI:MGI:5594378 +102638728 Gm35222 MGI:MGI:5594381 +102638729 Gm35223 MGI:MGI:5594382 +102638731 Gm35225 MGI:MGI:5594384 +102638732 Gm35226 MGI:MGI:5594385 +102638733 Gm35227 MGI:MGI:5594386 +102638734 Gm17163 MGI:MGI:4937990 +102638735 Gm15420 MGI:MGI:3705302|Ensembl:ENSMUSG00000087387 +102638736 Gm35228 MGI:MGI:5594387 +102638737 Gm35229 MGI:MGI:5594388 +102638738 Gm35230 MGI:MGI:5594389 +102638739 Gm35231 MGI:MGI:5594390 +102638740 Gm35232 MGI:MGI:5594391 +102638741 Gm35233 MGI:MGI:5594392 +102638742 Gm35234 MGI:MGI:5594393 +102638743 Gm35235 MGI:MGI:5594394 +102638744 Gm12784 MGI:MGI:3650358 +102638746 Gm35236 MGI:MGI:5594395 +102638747 Gm35237 MGI:MGI:5594396 +102638750 Gm35239 MGI:MGI:5594398 +102638751 Gm35240 MGI:MGI:5594399 +102638752 Gm35241 MGI:MGI:5594400 +102638753 Gm35242 MGI:MGI:5594401 +102638755 Gm35243 MGI:MGI:5594402 +102638756 Gm35244 MGI:MGI:5594403 +102638757 Gm35245 MGI:MGI:5594404 +102638758 Gm26597 MGI:MGI:5477091 +102638759 Gm35246 MGI:MGI:5594405 +102638760 Gm35247 MGI:MGI:5594406 +102638761 LOC102638761 - +102638762 Gm35248 MGI:MGI:5594407 +102638763 Gm12615 MGI:MGI:3649882 +102638764 Gm35249 MGI:MGI:5594408 +102638765 Gm35250 MGI:MGI:5594409 +102638766 Gm35251 MGI:MGI:5594410 +102638767 Gm35252 MGI:MGI:5594411 +102638768 Gm35253 MGI:MGI:5594412 +102638769 Gm26808 MGI:MGI:5477302 +102638770 Gm35254 MGI:MGI:5594413 +102638771 Gm35255 MGI:MGI:5594414 +102638772 Gm35256 MGI:MGI:5594415 +102638773 Gm38511 MGI:MGI:5621396 +102638774 Gm35257 MGI:MGI:5594416 +102638775 Gm21836 MGI:MGI:5434000 +102638777 Gm35259 MGI:MGI:5594418 +102638778 Gm35260 MGI:MGI:5594419 +102638779 Gm35261 MGI:MGI:5594420 +102638780 Gm35262 MGI:MGI:5594421 +102638781 Gm35263 MGI:MGI:5594422 +102638782 Gm35264 MGI:MGI:5594423 +102638783 Gm35265 MGI:MGI:5594424 +102638784 Gm35266 MGI:MGI:5594425 +102638785 LOC102638785 - +102638786 Gm35267 MGI:MGI:5594426 +102638787 Gm35268 MGI:MGI:5594427 +102638788 Gm35269 MGI:MGI:5594428 +102638792 Gm35271 MGI:MGI:5594430 +102638793 Gm29554 MGI:MGI:5580260 +102638796 Gm35274 MGI:MGI:5594433|Ensembl:ENSMUSG00000112524 +102638797 LOC102638797 - +102638802 Gm35279 MGI:MGI:5594438 +102638803 Gm35280 MGI:MGI:5594439 +102638804 Gm35281 MGI:MGI:5594440 +102638805 Gm35282 MGI:MGI:5594441 +102638806 Gm35283 MGI:MGI:5594442 +102638807 Gm35284 MGI:MGI:5594443 +102638808 Gm35285 MGI:MGI:5594444 +102638809 Gm20428 MGI:MGI:5141893 +102638811 Gm35287 MGI:MGI:5594446 +102638812 Gm35288 MGI:MGI:5594447 +102638813 Gm35289 MGI:MGI:5594448 +102638814 Gm35290 MGI:MGI:5594449 +102638815 Gm35291 MGI:MGI:5594450 +102638818 Gm26697 MGI:MGI:5477191 +102638819 Gm35294 MGI:MGI:5594453 +102638820 Gm35295 MGI:MGI:5594454 +102638821 Gm35296 MGI:MGI:5594455 +102638822 Gm35297 MGI:MGI:5594456 +102638824 Gm35298 MGI:MGI:5594457 +102638825 Gm35299 MGI:MGI:5594458 +102638826 Gm35300 MGI:MGI:5594459 +102638827 Gm14696 MGI:MGI:3705257|Ensembl:ENSMUSG00000087369 +102638828 Gm35301 MGI:MGI:5594460 +102638829 Gm21779 MGI:MGI:5433943 +102638830 Gm28073 MGI:MGI:5578779|Ensembl:ENSMUSG00000101424 +102638831 Gm35302 MGI:MGI:5594461 +102638832 Gm28590 MGI:MGI:5579296|Ensembl:ENSMUSG00000099960 +102638833 Gm35303 MGI:MGI:5594462 +102638835 Gm16263 MGI:MGI:3826536 +102638836 Gm35305 MGI:MGI:5594464 +102638837 Gm21964 MGI:MGI:5439433|Ensembl:ENSMUSG00000095941|Vega:OTTMUSG00000063001 +102638839 Gm35307 MGI:MGI:5594466 +102638840 Gm35308 MGI:MGI:5594467 +102638841 Gm35309 MGI:MGI:5594468 +102638842 Gm35310 MGI:MGI:5594469 +102638843 Gm35311 MGI:MGI:5594470 +102638844 Gm35312 MGI:MGI:5594471 +102638845 Gm35313 MGI:MGI:5594472 +102638846 Gm35314 MGI:MGI:5594473 +102638847 Gm35315 MGI:MGI:5594474|Ensembl:ENSMUSG00000109771|Vega:OTTMUSG00000060657 +102638848 Gm38512 MGI:MGI:5621397 +102638849 Gm15764 MGI:MGI:3783206 +102638850 LOC102638850 - +102638851 Gm17224 MGI:MGI:4938051 +102638853 Gm27227 MGI:MGI:5521070 +102638854 Gm15934 MGI:MGI:3801896 +102638855 Gm35317 MGI:MGI:5594476 +102638857 Gm35319 MGI:MGI:5594478 +102638859 Gm35321 MGI:MGI:5594480 +102638860 Gm35322 MGI:MGI:5594481 +102638861 Gm35323 MGI:MGI:5594482 +102638862 Gm35324 MGI:MGI:5594483 +102638863 Gm35325 MGI:MGI:5594484 +102638864 Gm29369 MGI:MGI:5580075 +102638865 Gm35326 MGI:MGI:5594485 +102638868 Gm35329 MGI:MGI:5594488 +102638869 Gm35330 MGI:MGI:5594489 +102638870 Gm29546 MGI:MGI:5580252 +102638871 Gm21720 MGI:MGI:5433884 +102638873 Gm35332 MGI:MGI:5594491 +102638874 Gm35333 MGI:MGI:5594492 +102638876 Gm35335 MGI:MGI:5594494 +102638878 LOC102638878 - +102638879 Gm12624 MGI:MGI:3650565 +102638880 Gm35337 MGI:MGI:5594496 +102638881 Gm35338 MGI:MGI:5594497 +102638882 Gm35339 MGI:MGI:5594498|Ensembl:ENSMUSG00000109179|Vega:OTTMUSG00000059322 +102638883 Gm35340 MGI:MGI:5594499 +102638884 Gm38513 MGI:MGI:5621398 +102638885 LOC102638885 - +102638886 Gm35341 MGI:MGI:5594500 +102638887 Gm35342 MGI:MGI:5594501 +102638888 LOC102638888 - +102638889 Gm35343 MGI:MGI:5594502 +102638890 LOC102638890 - +102638891 LOC102638891 - +102638892 Gm35344 MGI:MGI:5594503 +102638895 Gm35347 MGI:MGI:5594506 +102638896 Gm35348 MGI:MGI:5594507 +102638898 Gm35350 MGI:MGI:5594509 +102638900 Gm35351 MGI:MGI:5594510 +102638901 Gm35352 MGI:MGI:5594511 +102638902 Gm35353 MGI:MGI:5594512 +102638904 Gm21737 MGI:MGI:5433901 +102638905 LOC102638905 - +102638906 Gm29300 MGI:MGI:5580006 +102638908 Gm35355 MGI:MGI:5594514 +102638909 Gm35356 MGI:MGI:5594515 +102638910 Gm35357 MGI:MGI:5594516 +102638911 Gm35358 MGI:MGI:5594517 +102638912 Gm35359 MGI:MGI:5594518 +102638913 LOC102638913 Ensembl:ENSMUSG00000095577|Vega:OTTMUSG00000034588 +102638914 Gm35360 MGI:MGI:5594519 +102638915 Gm35361 MGI:MGI:5594520 +102638916 Gm35362 MGI:MGI:5594521 +102638917 Gm35363 MGI:MGI:5594522 +102638918 Gm35364 MGI:MGI:5594523 +102638919 Gm35365 MGI:MGI:5594524 +102638921 Gm21917 MGI:MGI:5434081 +102638922 Gm35366 MGI:MGI:5594525 +102638923 Gm35367 MGI:MGI:5594526 +102638924 Gm35368 MGI:MGI:5594527 +102638925 Gm35369 MGI:MGI:5594528 +102638927 Gm35371 MGI:MGI:5594530 +102638929 Gm35372 MGI:MGI:5594531 +102638930 Gm35373 MGI:MGI:5594532 +102638931 Gm35374 MGI:MGI:5594533 +102638933 Fhad1os2 MGI:MGI:3651870 +102638935 LOC102638935 - +102638938 Gm35378 MGI:MGI:5594537 +102638939 Gm35379 MGI:MGI:5594538 +102638940 LOC102638940 - +102638941 Gm12853 MGI:MGI:3650185 +102638942 Gm28685 MGI:MGI:5579391 +102638943 Gm35380 MGI:MGI:5594539 +102638944 Gm35381 MGI:MGI:5594540 +102638947 Gm26844 MGI:MGI:5477338|Ensembl:ENSMUSG00000097522 +102638948 Gm35383 MGI:MGI:5594542 +102638949 Gm35384 MGI:MGI:5594543 +102638951 Gm35386 MGI:MGI:5594545 +102638952 Gm35387 MGI:MGI:5594546 +102638953 Gm35388 MGI:MGI:5594547 +102638954 Gm35389 MGI:MGI:5594548 +102638956 Gm35391 MGI:MGI:5594550 +102638957 Gm35392 MGI:MGI:5594551|Ensembl:ENSMUSG00000109748 +102638958 Gm35393 MGI:MGI:5594552 +102638959 Gm35394 MGI:MGI:5594553|Ensembl:ENSMUSG00000105686 +102638960 Gm26838 MGI:MGI:5477332 +102638961 Gm35395 MGI:MGI:5594554 +102638962 LOC102638962 - +102638963 Gm35396 MGI:MGI:5594555 +102638964 Gm35397 MGI:MGI:5594556 +102638965 Gm35398 MGI:MGI:5594557 +102638966 Gm35399 MGI:MGI:5594558 +102638967 Gm35400 MGI:MGI:5594559 +102638969 Gm35402 MGI:MGI:5594561 +102638970 Gm35403 MGI:MGI:5594562 +102638971 Gm35404 MGI:MGI:5594563|Ensembl:ENSMUSG00000112871 +102638972 Gm35405 MGI:MGI:5594564 +102638973 Gm35406 MGI:MGI:5594565 +102638974 Gm24208 MGI:MGI:5453985 +102638975 Gm35407 MGI:MGI:5594566 +102638976 Gm35408 MGI:MGI:5594567 +102638977 Gm35409 MGI:MGI:5594568 +102638978 Gm35410 MGI:MGI:5594569 +102638980 Gm35412 MGI:MGI:5594571 +102638981 Gm29652 MGI:MGI:5580358 +102638982 Gm12639 MGI:MGI:3649270 +102638983 Gm35413 MGI:MGI:5594572 +102638987 Gm35415 MGI:MGI:5594574 +102638988 Gm35416 MGI:MGI:5594575 +102638990 Gm35417 MGI:MGI:5594576 +102638991 Gm35418 MGI:MGI:5594577 +102638992 Gm35419 MGI:MGI:5594578 +102638993 LOC102638993 - +102638994 Gm12616 MGI:MGI:3649883 +102638995 Gm35420 MGI:MGI:5594579 +102638997 Gm35422 MGI:MGI:5594581 +102638998 Gm35423 MGI:MGI:5594582 +102638999 LOC102638999 - +102639000 Gm35424 MGI:MGI:5594583 +102639001 Gm35425 MGI:MGI:5594584 +102639002 Gm35426 MGI:MGI:5594585 +102639003 Gm35427 MGI:MGI:5594586 +102639005 Gm16096 MGI:MGI:3801985 +102639006 Gm22146 MGI:MGI:5451923 +102639007 Gm35429 MGI:MGI:5594588 +102639008 Gm35430 MGI:MGI:5594589 +102639009 Gm13630 MGI:MGI:3650561 +102639010 Gm35431 MGI:MGI:5594590 +102639011 Gm35432 MGI:MGI:5594591 +102639012 Gm35433 MGI:MGI:5594592 +102639013 LOC102639013 - +102639014 Gm35434 MGI:MGI:5594593 +102639015 Gm35435 MGI:MGI:5594594 +102639017 Gm35436 MGI:MGI:5594595 +102639018 Gm35437 MGI:MGI:5594596 +102639019 Gm35438 MGI:MGI:5594597 +102639020 Gm12781 MGI:MGI:3649569 +102639021 LOC102639021 - +102639022 Gm35439 MGI:MGI:5594598 +102639023 Gm35440 MGI:MGI:5594599 +102639024 Gm28489 MGI:MGI:5579195 +102639025 LOC102639025 - +102639027 Gm28871 MGI:MGI:5579577 +102639028 Gm28969 MGI:MGI:5579675 +102639030 Gm35443 MGI:MGI:5594602 +102639031 Gm35444 MGI:MGI:5594603 +102639032 Gm35445 MGI:MGI:5594604 +102639033 Gm35446 MGI:MGI:5594605 +102639036 Gm35449 MGI:MGI:5594608 +102639037 LOC102639037 - +102639038 Gm35450 MGI:MGI:5594609 +102639040 LOC102639040 - +102639041 Gm35452 MGI:MGI:5594611 +102639042 Gm35453 MGI:MGI:5594612 +102639043 Gm11608 MGI:MGI:3651337 +102639044 LOC102639044 - +102639045 Gm15564 MGI:MGI:3783013 +102639046 Gm35454 MGI:MGI:5594613 +102639047 Gm35455 MGI:MGI:5594614 +102639048 Gm35456 MGI:MGI:5594615 +102639049 Gm35457 MGI:MGI:5594616 +102639051 Gm35458 MGI:MGI:5594617 +102639053 Gm16222 MGI:MGI:3801901|Ensembl:ENSMUSG00000086798 +102639054 LOC102639054 - +102639055 Gm35459 MGI:MGI:5594618 +102639056 Gm35460 MGI:MGI:5594619 +102639058 Gm35462 MGI:MGI:5594621 +102639059 Gm35463 MGI:MGI:5594622 +102639060 Gm35464 MGI:MGI:5594623 +102639062 Gm35465 MGI:MGI:5594624 +102639063 Gm35466 MGI:MGI:5594625 +102639064 Gm35467 MGI:MGI:5594626 +102639065 Gm35468 MGI:MGI:5594627 +102639066 Gm35469 MGI:MGI:5594628 +102639067 Gm38514 MGI:MGI:5621399 +102639068 Gm35470 MGI:MGI:5594629 +102639069 Gm35471 MGI:MGI:5594630 +102639070 Gm35472 MGI:MGI:5594631 +102639071 Gm35473 MGI:MGI:5594632 +102639072 Gm35474 MGI:MGI:5594633 +102639074 Gm35476 MGI:MGI:5594635 +102639075 Gm26907 MGI:MGI:5477401 +102639076 LOC102639076 - +102639077 Gm35477 MGI:MGI:5594636 +102639078 Gm35478 MGI:MGI:5594637 +102639079 Gm35479 MGI:MGI:5594638 +102639080 Gm35480 MGI:MGI:5594639 +102639081 Gm35481 MGI:MGI:5594640 +102639082 Gm35482 MGI:MGI:5594641 +102639084 Gm35484 MGI:MGI:5594643 +102639086 Gm15551 MGI:MGI:3783000 +102639087 Gm35486 MGI:MGI:5594645 +102639088 Gm35487 MGI:MGI:5594646 +102639089 Gm21768 MGI:MGI:5433932 +102639090 Gm35488 MGI:MGI:5594647 +102639091 LOC102639091 - +102639094 Gm28102 MGI:MGI:5578808 +102639095 Gm28531 MGI:MGI:5579237 +102639096 Gm28929 MGI:MGI:5579635 +102639099 Gm35493 MGI:MGI:5594652 +102639100 Gm35494 MGI:MGI:5594653 +102639102 Gm35496 MGI:MGI:5594655 +102639103 Gm35497 MGI:MGI:5594656 +102639104 LOC102639104 - +102639105 Gm35498 MGI:MGI:5594657 +102639107 Gm35500 MGI:MGI:5594659 +102639108 Gm28877 MGI:MGI:5579583 +102639109 LOC102639109 - +102639110 Gm35501 MGI:MGI:5594660 +102639111 Gm35502 MGI:MGI:5594661 +102639115 Gm15343 MGI:MGI:3705126 +102639117 LOC102639117 Ensembl:ENSMUSG00000096872|Vega:OTTMUSG00000045978 +102639118 Gm35506 MGI:MGI:5594665 +102639119 Gm35507 MGI:MGI:5594666|Ensembl:ENSMUSG00000105102 +102639120 Gm35508 MGI:MGI:5594667 +102639121 Gm35509 MGI:MGI:5594668 +102639122 Gm35510 MGI:MGI:5594669 +102639124 Gm29319 MGI:MGI:5580025 +102639127 LOC102639127 - +102639128 Gm35514 MGI:MGI:5594673|Ensembl:ENSMUSG00000113595 +102639129 Gm35515 MGI:MGI:5594674 +102639131 Gm35517 MGI:MGI:5594676 +102639132 Gm21885 MGI:MGI:5434049 +102639135 Gm16347 MGI:MGI:3840141 +102639136 Gm35520 MGI:MGI:5594679 +102639137 Gm26515 MGI:MGI:5477009 +102639138 Gm35521 MGI:MGI:5594680|Ensembl:ENSMUSG00000109579 +102639139 Gm35522 MGI:MGI:5594681 +102639141 Gm35524 MGI:MGI:5594683 +102639142 Gm35525 MGI:MGI:5594684 +102639143 LOC102639143 - +102639145 LOC102639145 - +102639146 Gm35527 MGI:MGI:5594686 +102639148 Gm35528 MGI:MGI:5594687 +102639149 Gm35529 MGI:MGI:5594688 +102639151 Gm35531 MGI:MGI:5594690 +102639152 Gm35532 MGI:MGI:5594691 +102639153 Gm35533 MGI:MGI:5594692|Ensembl:ENSMUSG00000112831 +102639154 Gm35534 MGI:MGI:5594693 +102639156 Gm35535 MGI:MGI:5594694 +102639157 Gm35536 MGI:MGI:5594695 +102639158 Gm28258 MGI:MGI:5578964 +102639159 Gm21763 MGI:MGI:5433927 +102639160 Gm35537 MGI:MGI:5594696 +102639165 Gm35540 MGI:MGI:5594699 +102639166 Gm35541 MGI:MGI:5594700 +102639167 Gm35542 MGI:MGI:5594701 +102639168 Gm35543 MGI:MGI:5594702 +102639169 Gm20387 MGI:MGI:5141852 +102639170 LOC102639170 - +102639171 Gm35544 MGI:MGI:5594703 +102639172 LOC102639172 - +102639173 LOC102639173 - +102639174 Gm35545 MGI:MGI:5594704 +102639175 Gm35546 MGI:MGI:5594705 +102639176 Gm35547 MGI:MGI:5594706 +102639177 Gm35548 MGI:MGI:5594707|Ensembl:ENSMUSG00000111697 +102639178 Gm35549 MGI:MGI:5594708 +102639179 Gm35550 MGI:MGI:5594709 +102639180 Gm35551 MGI:MGI:5594710 +102639181 Gm35552 MGI:MGI:5594711 +102639182 Gm38515 MGI:MGI:5621400 +102639183 Gm35553 MGI:MGI:5594712 +102639184 LOC102639184 - +102639185 Gm35554 MGI:MGI:5594713 +102639186 Gm26644 MGI:MGI:5477138 +102639187 LOC102639187 - +102639188 Gm27008 MGI:MGI:5504123 +102639189 Gm35555 MGI:MGI:5594714 +102639190 Gm35556 MGI:MGI:5594715 +102639191 LOC102639191 - +102639192 Gm35558 MGI:MGI:5594717 +102639193 Gm12927 MGI:MGI:3651776|Ensembl:ENSMUSG00000085203 +102639194 Gm12851 MGI:MGI:3649254 +102639196 Gm21766 MGI:MGI:5433930 +102639198 Gm35561 MGI:MGI:5594720 +102639199 Gm35562 MGI:MGI:5594721 +102639202 Gm35564 MGI:MGI:5594723 +102639203 Gm35565 MGI:MGI:5594724 +102639204 LOC102639204 - +102639205 Gm35566 MGI:MGI:5594725 +102639206 Gm35567 MGI:MGI:5594726 +102639207 Gm35568 MGI:MGI:5594727 +102639208 Gm38516 MGI:MGI:5621401 +102639209 Gm35569 MGI:MGI:5594728 +102639210 Gm35570 MGI:MGI:5594729 +102639212 Gm35572 MGI:MGI:5594731 +102639213 Gm35573 MGI:MGI:5594732 +102639214 Gm35574 MGI:MGI:5594733 +102639215 Gm35575 MGI:MGI:5594734 +102639216 Gm35576 MGI:MGI:5594735 +102639217 Gm35577 MGI:MGI:5594736 +102639218 Gm35578 MGI:MGI:5594737 +102639219 Gm35579 MGI:MGI:5594738 +102639220 Gm17430 MGI:MGI:4937064 +102639221 Gm35580 MGI:MGI:5594739 +102639222 Gm35581 MGI:MGI:5594740 +102639223 Gm35582 MGI:MGI:5594741 +102639225 Gm35584 MGI:MGI:5594743|Ensembl:ENSMUSG00000102936 +102639226 Gm35585 MGI:MGI:5594744 +102639227 Gm35586 MGI:MGI:5594745 +102639228 Gm35587 MGI:MGI:5594746 +102639229 Gm35588 MGI:MGI:5594747 +102639230 Gm29399 MGI:MGI:5580105 +102639232 Gm12688 MGI:MGI:3650434 +102639234 Gm21879 MGI:MGI:5434043 +102639235 Gm35591 MGI:MGI:5594750 +102639236 Gm35592 MGI:MGI:5594751 +102639237 Gm35593 MGI:MGI:5594752 +102639239 Gm35595 MGI:MGI:5594754 +102639240 Gm35596 MGI:MGI:5594755 +102639241 Gm35597 MGI:MGI:5594756 +102639242 Gm35598 MGI:MGI:5594757 +102639243 Gm35599 MGI:MGI:5594758 +102639244 Gm35600 MGI:MGI:5594759 +102639246 Gm35601 MGI:MGI:5594760 +102639247 Gm27887 MGI:MGI:5531269 +102639248 Gm35602 MGI:MGI:5594761 +102639249 Gm35603 MGI:MGI:5594762 +102639251 Znf660 - +102639253 Gm35606 MGI:MGI:5594765 +102639254 Gm35607 MGI:MGI:5594766 +102639255 Gm35608 MGI:MGI:5594767 +102639257 Gm35610 MGI:MGI:5594769 +102639258 Gm35611 MGI:MGI:5594770 +102639259 Gm35612 MGI:MGI:5594771 +102639261 Gm35614 MGI:MGI:5594773 +102639262 Gm35615 MGI:MGI:5594774 +102639263 Gm28990 MGI:MGI:5579696 +102639267 Gm35618 MGI:MGI:5594777 +102639268 Gm13830 MGI:MGI:3651141 +102639269 Gm35619 MGI:MGI:5594778 +102639270 Gm35620 MGI:MGI:5594779 +102639271 Gm35621 MGI:MGI:5594780 +102639272 Gm35622 MGI:MGI:5594781 +102639274 Gm35623 MGI:MGI:5594782 +102639275 Gm35624 MGI:MGI:5594783 +102639276 Gm26534 MGI:MGI:5477028 +102639277 Gm35625 MGI:MGI:5594784 +102639278 Gm35626 MGI:MGI:5594785 +102639279 Gm35627 MGI:MGI:5594786 +102639280 Gm35628 MGI:MGI:5594787 +102639281 Gm35629 MGI:MGI:5594788 +102639282 Gm35630 MGI:MGI:5594789 +102639283 Gm13584 MGI:MGI:3650662 +102639284 Gm35631 MGI:MGI:5594790 +102639285 Gm35632 MGI:MGI:5594791 +102639287 Gm35634 MGI:MGI:5594793 +102639288 Gm35635 MGI:MGI:5594794 +102639289 Gm35636 MGI:MGI:5594795 +102639290 Gm11963 MGI:MGI:3652248 +102639292 Gm35638 MGI:MGI:5594797 +102639293 Gm35639 MGI:MGI:5594798 +102639296 Gm35641 MGI:MGI:5594800 +102639299 Gm35644 MGI:MGI:5594803 +102639300 Gm15187 MGI:MGI:3705560 +102639301 Gm35645 MGI:MGI:5594804 +102639302 Gm28459 MGI:MGI:5579165 +102639303 Gm28353 MGI:MGI:5579059 +102639304 Gm28074 MGI:MGI:5578780|Ensembl:ENSMUSG00000100715 +102639307 Gm35648 MGI:MGI:5594807 +102639308 Gm35649 MGI:MGI:5594808 +102639309 Gm35650 MGI:MGI:5594809 +102639311 Gm35652 MGI:MGI:5594811 +102639314 Gm35655 MGI:MGI:5594814 +102639315 LOC102639315 - +102639317 Gm35657 MGI:MGI:5594816 +102639318 Gm35658 MGI:MGI:5594817 +102639319 Gm35659 MGI:MGI:5594818 +102639321 Gm38518 MGI:MGI:5621403 +102639326 Gm35664 MGI:MGI:5594823 +102639328 Gm35665 MGI:MGI:5594824 +102639329 Gm35666 MGI:MGI:5594825 +102639331 Gm35667 MGI:MGI:5594826 +102639334 Gm35670 MGI:MGI:5594829 +102639335 Gm35671 MGI:MGI:5594830 +102639336 Gm35672 MGI:MGI:5594831 +102639337 LOC102639337 - +102639339 Gm26559 MGI:MGI:5477053 +102639340 Gm35674 MGI:MGI:5594833 +102639342 Gm35676 MGI:MGI:5594835 +102639343 Gm35677 MGI:MGI:5594836 +102639344 Gm35678 MGI:MGI:5594837 +102639345 Gm35679 MGI:MGI:5594838 +102639346 Gm35680 MGI:MGI:5594839 +102639347 Gm35681 MGI:MGI:5594840 +102639348 Gm35682 MGI:MGI:5594841 +102639350 Gm35684 MGI:MGI:5594843 +102639351 Gm15952 MGI:MGI:3802149 +102639352 Gm35685 MGI:MGI:5594844 +102639353 Gm35686 MGI:MGI:5594845 +102639354 Gm35687 MGI:MGI:5594846 +102639355 Gm35688 MGI:MGI:5594847 +102639356 LOC102639356 - +102639357 Gm35689 MGI:MGI:5594848 +102639358 Gm27197 MGI:MGI:5521040 +102639359 Gm35690 MGI:MGI:5594849 +102639360 Gm35691 MGI:MGI:5594850 +102639361 Gm35692 MGI:MGI:5594851 +102639363 Gm35693 MGI:MGI:5594852 +102639364 Gm35694 MGI:MGI:5594853 +102639365 Gm35695 MGI:MGI:5594854 +102639366 Gm35696 MGI:MGI:5594855 +102639367 Gm35697 MGI:MGI:5594856 +102639368 Gm35698 MGI:MGI:5594857 +102639369 Gm35699 MGI:MGI:5594858 +102639370 Gm35700 MGI:MGI:5594859 +102639371 Gm35701 MGI:MGI:5594860 +102639372 Gm35702 MGI:MGI:5594861 +102639373 Gm28382 MGI:MGI:5579088 +102639374 Gm35703 MGI:MGI:5594862 +102639375 Gm29514 MGI:MGI:5580220 +102639377 Gm35704 MGI:MGI:5594863 +102639378 Gm35705 MGI:MGI:5594864 +102639379 Gm35706 MGI:MGI:5594865 +102639380 Gm35707 MGI:MGI:5594866 +102639381 Gm35708 MGI:MGI:5594867 +102639383 Gm35710 MGI:MGI:5594869 +102639384 Gm35711 MGI:MGI:5594870 +102639385 LOC102639385 - +102639386 Gm35712 MGI:MGI:5594871 +102639387 Gm35713 MGI:MGI:5594872 +102639388 Gm35714 MGI:MGI:5594873 +102639389 Gm35715 MGI:MGI:5594874 +102639390 Gm35716 MGI:MGI:5594875 +102639392 Gm35718 MGI:MGI:5594877 +102639393 Gm35719 MGI:MGI:5594878 +102639394 Gm35720 MGI:MGI:5594879 +102639395 Gm35721 MGI:MGI:5594880 +102639396 Gm35722 MGI:MGI:5594881 +102639397 Gm35723 MGI:MGI:5594882 +102639398 Gm35724 MGI:MGI:5594883 +102639399 Gm35725 MGI:MGI:5594884|Ensembl:ENSMUSG00000113666 +102639400 Gm35726 MGI:MGI:5594885 +102639401 Gm35727 MGI:MGI:5594886 +102639403 Gm29401 MGI:MGI:5580107 +102639404 Gm26839 MGI:MGI:5477333|Ensembl:ENSMUSG00000097917 +102639406 Gm35730 MGI:MGI:5594889 +102639408 Gm35732 MGI:MGI:5594891 +102639409 Gm15461 MGI:MGI:3705274 +102639410 Gm35733 MGI:MGI:5594892 +102639411 Gm35734 MGI:MGI:5594893 +102639412 Gm38519 MGI:MGI:5621404 +102639413 Gm35735 MGI:MGI:5594894 +102639414 Gm35736 MGI:MGI:5594895 +102639416 Gm35738 MGI:MGI:5594897 +102639417 Gm26536 MGI:MGI:5477030 +102639419 Gm35739 MGI:MGI:5594898 +102639420 Gm35740 MGI:MGI:5594899 +102639421 Gm35741 MGI:MGI:5594900 +102639424 Gm35742 MGI:MGI:5594901 +102639427 Gm16169 MGI:MGI:3802011 +102639428 LOC102639428 - +102639430 Gm35745 MGI:MGI:5594904 +102639431 Gm35746 MGI:MGI:5594905 +102639432 Gm35747 MGI:MGI:5594906 +102639433 LOC102639433 - +102639434 Gm35748 MGI:MGI:5594907 +102639435 Gm35749 MGI:MGI:5594908 +102639436 Gm35750 MGI:MGI:5594909 +102639437 Gm35751 MGI:MGI:5594910 +102639438 Gm35752 MGI:MGI:5594911 +102639441 Gm35755 MGI:MGI:5594914 +102639442 Gm35756 MGI:MGI:5594915 +102639444 Gm24027 MGI:MGI:5453804 +102639445 Gm35758 MGI:MGI:5594917 +102639447 Gm29081 MGI:MGI:5579787|Ensembl:ENSMUSG00000099463 +102639448 Gm35760 MGI:MGI:5594919 +102639449 Gm35761 MGI:MGI:5594920 +102639450 Gm35762 MGI:MGI:5594921 +102639451 LOC102639451 - +102639452 LOC102639452 - +102639453 LOC102639453 - +102639454 Gm35763 MGI:MGI:5594922 +102639456 Gm38520 MGI:MGI:5621405 +102639457 Gm35764 MGI:MGI:5594923 +102639458 Gm35765 MGI:MGI:5594924 +102639459 Gm35766 MGI:MGI:5594925 +102639460 Gm35767 MGI:MGI:5594926 +102639461 Gm35768 MGI:MGI:5594927 +102639462 Gm35769 MGI:MGI:5594928 +102639464 Gm35771 MGI:MGI:5594930 +102639465 Gm35772 MGI:MGI:5594931 +102639466 Gm35773 MGI:MGI:5594932 +102639467 Gm35774 MGI:MGI:5594933 +102639468 Gm35775 MGI:MGI:5594934 +102639470 LOC102639470 - +102639471 Gm13599 MGI:MGI:3649283 +102639473 Gm14273 MGI:MGI:3649600|Ensembl:ENSMUSG00000085905 +102639474 Gm35778 MGI:MGI:5594937 +102639475 Gm35779 MGI:MGI:5594938 +102639476 Gm35780 MGI:MGI:5594939 +102639477 Gm35781 MGI:MGI:5594940 +102639478 Gm35782 MGI:MGI:5594941 +102639481 Gm35785 MGI:MGI:5594944 +102639482 Gm35786 MGI:MGI:5594945 +102639483 Gm35787 MGI:MGI:5594946 +102639484 Gm35788 MGI:MGI:5594947 +102639486 Gm35790 MGI:MGI:5594949 +102639490 Gm21858 MGI:MGI:5434022 +102639492 Gm35795 MGI:MGI:5594954 +102639493 Gm35796 MGI:MGI:5594955 +102639494 Gm28380 MGI:MGI:5579086 +102639496 Gm35797 MGI:MGI:5594956 +102639497 Gm35798 MGI:MGI:5594957 +102639498 Gm35799 MGI:MGI:5594958 +102639499 Gm35800 MGI:MGI:5594959 +102639500 Gm35801 MGI:MGI:5594960 +102639501 Gm35802 MGI:MGI:5594961 +102639502 Gm35803 MGI:MGI:5594962 +102639503 Gm35804 MGI:MGI:5594963 +102639505 LOC102639505 Ensembl:ENSMUSG00000095545|Vega:OTTMUSG00000034098 +102639507 Gm16168 MGI:MGI:3802010 +102639508 Gm35807 MGI:MGI:5594966 +102639509 Gm35808 MGI:MGI:5594967 +102639510 Gm35809 MGI:MGI:5594968 +102639511 Gm2065 MGI:MGI:3780232 +102639513 Gm35810 MGI:MGI:5594969 +102639516 Gm35813 MGI:MGI:5594972 +102639517 Gm35814 MGI:MGI:5594973 +102639518 LOC102639518 - +102639519 Gm35815 MGI:MGI:5594974 +102639520 Gm35816 MGI:MGI:5594975 +102639521 Gm29230 MGI:MGI:5579936 +102639522 Gm35817 MGI:MGI:5594976 +102639523 Gm35818 MGI:MGI:5594977 +102639528 Gm16335 MGI:MGI:3840152 +102639529 Gm35822 MGI:MGI:5594981|Ensembl:ENSMUSG00000107847 +102639530 Gm26832 MGI:MGI:5477326 +102639531 Gm35823 MGI:MGI:5594982 +102639532 Gm35824 MGI:MGI:5594983 +102639536 Gm35827 MGI:MGI:5594986 +102639537 Gm35828 MGI:MGI:5594987 +102639538 Gm35829 MGI:MGI:5594988 +102639540 Gm35831 MGI:MGI:5594990 +102639541 Gm35832 MGI:MGI:5594991 +102639542 Gm35833 MGI:MGI:5594992 +102639543 LOC102639543 Ensembl:ENSMUSG00000037849|Vega:OTTMUSG00000034635 +102639544 Gm35834 MGI:MGI:5594993 +102639545 Gm35835 MGI:MGI:5594994 +102639546 Gm35836 MGI:MGI:5594995 +102639547 Gm11832 MGI:MGI:3650310 +102639548 Gm13598 MGI:MGI:3649281 +102639549 Gm38521 MGI:MGI:5621406|Ensembl:ENSMUSG00000045106 +102639550 Gm35837 MGI:MGI:5594996 +102639551 Gm35838 MGI:MGI:5594997 +102639552 Gm12111 MGI:MGI:3649341 +102639554 Gm15928 MGI:MGI:3802091 +102639557 Gm35842 MGI:MGI:5595001 +102639558 Gm14582 MGI:MGI:3705178 +102639559 Gm35843 MGI:MGI:5595002 +102639560 Gm35844 MGI:MGI:5595003 +102639562 Gm35846 MGI:MGI:5595005 +102639563 Gm28683 MGI:MGI:5579389 +102639564 Gm35847 MGI:MGI:5595006 +102639565 Gm35848 MGI:MGI:5595007 +102639566 Ptgs2os2 MGI:MGI:5477181|Ensembl:ENSMUSG00000097754 +102639568 LOC102639568 - +102639569 Gm35849 MGI:MGI:5595008 +102639570 Gm35850 MGI:MGI:5595009 +102639571 Gm35851 MGI:MGI:5595010 +102639573 Gm35853 MGI:MGI:5595012 +102639574 Gm35854 MGI:MGI:5595013 +102639575 Gm35855 MGI:MGI:5595014 +102639576 Gm35856 MGI:MGI:5595015 +102639577 Gm35857 MGI:MGI:5595016 +102639580 Gm35860 MGI:MGI:5595019 +102639582 Gm16759 MGI:MGI:4439683 +102639584 LOC102639584 - +102639586 Gm35864 MGI:MGI:5595023 +102639587 Gm35865 MGI:MGI:5595024 +102639588 Gm11967 MGI:MGI:3650297|Ensembl:ENSMUSG00000084819 +102639589 Gm35866 MGI:MGI:5595025 +102639590 Gm35867 MGI:MGI:5595026 +102639593 Gm29079 MGI:MGI:5579785 +102639594 Gm35870 MGI:MGI:5595029 +102639595 Gm21829 MGI:MGI:5433993 +102639596 Gm28348 MGI:MGI:5579054 +102639597 Gm35871 MGI:MGI:5595030 +102639598 Gm14296 MGI:MGI:3708667|Ensembl:ENSMUSG00000074527|Vega:OTTMUSG00000016221 +102639599 Gm35872 MGI:MGI:5595031 +102639601 Gm35874 MGI:MGI:5595033 +102639602 Gm35875 MGI:MGI:5595034 +102639604 Gm35876 MGI:MGI:5595035 +102639606 Gm35878 MGI:MGI:5595037 +102639607 Gm35879 MGI:MGI:5595038 +102639608 Gm16725 MGI:MGI:4439649 +102639609 Gm35880 MGI:MGI:5595039 +102639611 Gm35881 MGI:MGI:5595040 +102639612 Gm35882 MGI:MGI:5595041 +102639614 Gm35883 MGI:MGI:5595042 +102639615 Gm35884 MGI:MGI:5595043 +102639616 Gm13773 MGI:MGI:3712316 +102639617 Gm13601 MGI:MGI:3649286 +102639618 Gm35885 MGI:MGI:5595044 +102639619 Gm35886 MGI:MGI:5595045 +102639620 Gm35887 MGI:MGI:5595046 +102639622 Gm35888 MGI:MGI:5595047 +102639623 Gm15923 MGI:MGI:3801851 +102639624 Gm35889 MGI:MGI:5595048 +102639625 Gm35890 MGI:MGI:5595049 +102639626 Gm35891 MGI:MGI:5595050 +102639628 Gm35893 MGI:MGI:5595052 +102639629 Gm35894 MGI:MGI:5595053 +102639630 Gm35895 MGI:MGI:5595054 +102639633 Gm12740 MGI:MGI:3651641 +102639635 Gm35899 MGI:MGI:5595058 +102639636 Gm35900 MGI:MGI:5595059 +102639637 Gm35901 MGI:MGI:5595060 +102639638 Gm35902 MGI:MGI:5595061 +102639642 Gm15895 MGI:MGI:3802071 +102639643 Gm35906 MGI:MGI:5595065 +102639644 Gm35907 MGI:MGI:5595066 +102639645 LOC102639645 - +102639646 Gm35908 MGI:MGI:5595067 +102639647 Gm35909 MGI:MGI:5595068 +102639650 Gm35911 MGI:MGI:5595070|Ensembl:ENSMUSG00000105078|Vega:OTTMUSG00000053571 +102639651 Gm35912 MGI:MGI:5595071 +102639652 Gm35913 MGI:MGI:5595072 +102639653 LOC102639653 Ensembl:ENSMUSG00000094932|Vega:OTTMUSG00000033913 +102639655 Gm13562 MGI:MGI:3651238 +102639656 Gm35915 MGI:MGI:5595074 +102639657 Gm35916 MGI:MGI:5595075 +102639658 Gm35917 MGI:MGI:5595076 +102639660 Gm35918 MGI:MGI:5595077 +102639661 Gm35919 MGI:MGI:5595078 +102639662 Gm35920 MGI:MGI:5595079 +102639664 Gm35922 MGI:MGI:5595081 +102639665 Gm35923 MGI:MGI:5595082 +102639667 Gm35925 MGI:MGI:5595084 +102639668 Gm29169 MGI:MGI:5579875 +102639671 Gm35928 MGI:MGI:5595087 +102639672 LOC102639672 - +102639673 Gm35929 MGI:MGI:5595088 +102639674 Gm35930 MGI:MGI:5595089 +102639675 Gm35931 MGI:MGI:5595090 +102639677 Gm35932 MGI:MGI:5595091 +102639678 Gm35933 MGI:MGI:5595092 +102639679 Gm35934 MGI:MGI:5595093 +102639680 Gm35935 MGI:MGI:5595094 +102639681 Gm35936 MGI:MGI:5595095 +102639682 Gm35937 MGI:MGI:5595096 +102639683 LOC102639683 - +102639684 Gm35938 MGI:MGI:5595097 +102639685 Gm35939 MGI:MGI:5595098 +102639686 Gm35940 MGI:MGI:5595099 +102639687 Gm35941 MGI:MGI:5595100 +102639688 Gm38522 MGI:MGI:5621407 +102639689 Gm35942 MGI:MGI:5595101 +102639690 Gm35943 MGI:MGI:5595102 +102639692 Gm35945 MGI:MGI:5595104 +102639693 Gm35946 MGI:MGI:5595105 +102639695 Gm35948 MGI:MGI:5595107 +102639699 LOC102639699 - +102639700 LOC102639700 - +102639701 Gm35952 MGI:MGI:5595111 +102639702 Gm35953 MGI:MGI:5595112 +102639704 Gm35955 MGI:MGI:5595114 +102639705 Gm35956 MGI:MGI:5595115 +102639706 Gm28776 MGI:MGI:5579482 +102639707 Gm35957 MGI:MGI:5595116 +102639708 Gm21758 MGI:MGI:5433922 +102639709 Gm28589 MGI:MGI:5579295 +102639711 Gm35959 MGI:MGI:5595118 +102639712 Gm35960 MGI:MGI:5595119 +102639713 LOC102639713 - +102639714 Gm35961 MGI:MGI:5595120 +102639716 Gm35963 MGI:MGI:5595122|Ensembl:ENSMUSG00000110212 +102639717 Gm15894 MGI:MGI:3801859 +102639719 LOC102639719 - +102639720 Gm15083 MGI:MGI:3705191 +102639723 Gm35966 MGI:MGI:5595125 +102639724 Gm35967 MGI:MGI:5595126 +102639725 Gm35968 MGI:MGI:5595127 +102639726 Gm35969 MGI:MGI:5595128 +102639727 Gm35970 MGI:MGI:5595129 +102639728 Gm35971 MGI:MGI:5595130 +102639729 Gm35972 MGI:MGI:5595131 +102639730 Gm35973 MGI:MGI:5595132 +102639731 LOC102639731 - +102639732 Gm35974 MGI:MGI:5595133 +102639733 Gm35975 MGI:MGI:5595134 +102639734 Gm35976 MGI:MGI:5595135 +102639735 Gm35977 MGI:MGI:5595136 +102639736 Gm35978 MGI:MGI:5595137 +102639737 Gm35979 MGI:MGI:5595138 +102639738 Gm17021 MGI:MGI:4937848|Ensembl:ENSMUSG00000091661 +102639740 Gm35981 MGI:MGI:5595140 +102639741 Gm14009 MGI:MGI:3652195 +102639742 Gm35982 MGI:MGI:5595141 +102639743 Gm35983 MGI:MGI:5595142 +102639746 Gm29595 MGI:MGI:5580301 +102639747 Gm35986 MGI:MGI:5595145 +102639748 Gm35987 MGI:MGI:5595146 +102639749 Gm26230 MGI:MGI:5456007 +102639750 Gm35988 MGI:MGI:5595147 +102639751 Gm35989 MGI:MGI:5595148 +102639752 Gm15241 MGI:MGI:3705127 +102639754 Gm28677 MGI:MGI:5579383 +102639755 Gm35991 MGI:MGI:5595150 +102639756 Gm35992 MGI:MGI:5595151 +102639757 Gm35993 MGI:MGI:5595152 +102639758 LOC102639758 - +102639759 Gm35994 MGI:MGI:5595153 +102639760 Gm35995 MGI:MGI:5595154 +102639761 Gm35996 MGI:MGI:5595155 +102639762 LOC102639762 - +102639763 Gm35997 MGI:MGI:5595156 +102639764 Gm35998 MGI:MGI:5595157 +102639765 Gm29260 MGI:MGI:5579966|Ensembl:ENSMUSG00000100832 +102639766 Gm35999 MGI:MGI:5595158 +102639767 Gm13748 MGI:MGI:3702115 +102639768 Gm36000 MGI:MGI:5595159 +102639769 Gm36001 MGI:MGI:5595160 +102639771 Gm36002 MGI:MGI:5595161 +102639772 Gm36003 MGI:MGI:5595162 +102639773 Gm36004 MGI:MGI:5595163 +102639774 Gm36005 MGI:MGI:5595164 +102639775 Gm36006 MGI:MGI:5595165 +102639776 Gm36007 MGI:MGI:5595166 +102639777 Gm36008 MGI:MGI:5595167 +102639779 Gm36010 MGI:MGI:5595169 +102639780 Gm36011 MGI:MGI:5595170|Ensembl:ENSMUSG00000109003 +102639781 Gm36012 MGI:MGI:5595171 +102639782 Gm36013 MGI:MGI:5595172 +102639784 Gm28079 MGI:MGI:5578785 +102639787 Gm36017 MGI:MGI:5595176|Ensembl:ENSMUSG00000104800 +102639789 Gm36019 MGI:MGI:5595178 +102639792 Gm36022 MGI:MGI:5595181 +102639793 Gm36023 MGI:MGI:5595182 +102639794 LOC102639794 - +102639795 Gm36024 MGI:MGI:5595183 +102639796 Gm36025 MGI:MGI:5595184 +102639797 Gm15767 MGI:MGI:3783209 +102639798 LOC102639798 - +102639799 Gm36026 MGI:MGI:5595185 +102639801 Gm36027 MGI:MGI:5595186 +102639802 Gm36028 MGI:MGI:5595187|Ensembl:ENSMUSG00000108763|Vega:OTTMUSG00000058846 +102639803 Gm36029 MGI:MGI:5595188 +102639805 Gm36031 MGI:MGI:5595190 +102639806 Gm36032 MGI:MGI:5595191 +102639808 Gm36033 MGI:MGI:5595192 +102639809 Gm36034 MGI:MGI:5595193 +102639810 Gm36035 MGI:MGI:5595194 +102639811 LOC102639811 - +102639812 Gm36036 MGI:MGI:5595195 +102639813 Gm29010 MGI:MGI:5579716 +102639814 LOC102639814 - +102639815 Gm36037 MGI:MGI:5595196 +102639816 Gm36038 MGI:MGI:5595197 +102639818 Gm36040 MGI:MGI:5595199 +102639819 Gm36041 MGI:MGI:5595200 +102639821 Gm36043 MGI:MGI:5595202 +102639822 Gm36044 MGI:MGI:5595203 +102639823 Gm36045 MGI:MGI:5595204 +102639824 Gm36046 MGI:MGI:5595205 +102639825 Gm36047 MGI:MGI:5595206 +102639826 Gm36048 MGI:MGI:5595207 +102639828 Gm36049 MGI:MGI:5595208 +102639830 Gm29073 MGI:MGI:5579779 +102639835 Gm36055 MGI:MGI:5595214 +102639836 Gm36056 MGI:MGI:5595215 +102639837 Gm13840 MGI:MGI:3649479 +102639840 Gm36059 MGI:MGI:5595218 +102639841 Gm26588 MGI:MGI:5477082 +102639842 Gm36060 MGI:MGI:5595219 +102639843 Gm36061 MGI:MGI:5595220 +102639844 Gm36062 MGI:MGI:5595221 +102639846 Gm28980 MGI:MGI:5579686 +102639847 LOC102639847 - +102639848 Gm12532 MGI:MGI:3650618 +102639849 Gm36063 MGI:MGI:5595222 +102639851 Gm36065 MGI:MGI:5595224 +102639852 Gm36066 MGI:MGI:5595225 +102639853 Gm36067 MGI:MGI:5595226 +102639854 Gm36068 MGI:MGI:5595227 +102639855 Gm36069 MGI:MGI:5595228 +102639856 Gm36070 MGI:MGI:5595229 +102639857 Gm36071 MGI:MGI:5595230 +102639859 Gm36073 MGI:MGI:5595232 +102639860 Gm36074 MGI:MGI:5595233 +102639862 Gm21734 MGI:MGI:5433898 +102639863 Gm21777 MGI:MGI:5433941 +102639864 Gm36076 MGI:MGI:5595235 +102639866 Gm36077 MGI:MGI:5595236 +102639867 Gm36078 MGI:MGI:5595237 +102639868 Gm36079 MGI:MGI:5595238|Ensembl:ENSMUSG00000095029 +102639870 Gm38523 MGI:MGI:5621408 +102639872 Gm36082 MGI:MGI:5595241 +102639875 Gm36084 MGI:MGI:5595243 +102639877 Gm24333 MGI:MGI:5454110 +102639878 Gm36086 MGI:MGI:5595245 +102639880 Gm29240 MGI:MGI:5579946 +102639881 Gm36088 MGI:MGI:5595247 +102639882 LOC102639882 - +102639883 Gm36089 MGI:MGI:5595248 +102639884 Gm36090 MGI:MGI:5595249 +102639885 Gm36091 MGI:MGI:5595250 +102639886 Gm36092 MGI:MGI:5595251 +102639888 LOC102639888 Ensembl:ENSMUSG00000091558 +102639889 Gm29593 MGI:MGI:5580299 +102639891 Gm36095 MGI:MGI:5595254 +102639892 Gm36096 MGI:MGI:5595255 +102639893 Gm36097 MGI:MGI:5595256 +102639895 Gm28870 MGI:MGI:5579576 +102639897 Gm36099 MGI:MGI:5595258 +102639899 Gm36101 MGI:MGI:5595260 +102639900 Gm36102 MGI:MGI:5595261 +102639902 Gm36103 MGI:MGI:5595262 +102639904 Gm36105 MGI:MGI:5595264 +102639905 Gm36106 MGI:MGI:5595265 +102639906 Gm36107 MGI:MGI:5595266 +102639908 Gm36109 MGI:MGI:5595268 +102639909 Gm36110 MGI:MGI:5595269 +102639910 Gm36111 MGI:MGI:5595270 +102639911 Gm36112 MGI:MGI:5595271 +102639912 LOC102639912 - +102639913 Gm36113 MGI:MGI:5595272 +102639916 Gm36115 MGI:MGI:5595274 +102639917 Gm36116 MGI:MGI:5595275 +102639918 Gm36117 MGI:MGI:5595276 +102639919 Gm36118 MGI:MGI:5595277 +102639920 Gm36119 MGI:MGI:5595278 +102639921 Gm36120 MGI:MGI:5595279 +102639922 Gm10157 MGI:MGI:3642264 +102639923 Gm36121 MGI:MGI:5595280 +102639924 Gm36122 MGI:MGI:5595281 +102639925 Gm36123 MGI:MGI:5595282 +102639926 Gm36124 MGI:MGI:5595283 +102639928 Gm36126 MGI:MGI:5595285 +102639929 Gm36127 MGI:MGI:5595286 +102639930 Gm36128 MGI:MGI:5595287 +102639931 Gm36129 MGI:MGI:5595288 +102639932 Gm36130 MGI:MGI:5595289 +102639933 Gm36131 MGI:MGI:5595290 +102639934 Astx4d MGI:MGI:3705250 +102639935 Gm36132 MGI:MGI:5595291 +102639936 Gm36133 MGI:MGI:5595292 +102639937 Gm15205 MGI:MGI:3826535 +102639938 Gm21787 MGI:MGI:5433951 +102639939 Gm36134 MGI:MGI:5595293 +102639940 Gm36135 MGI:MGI:5595294 +102639941 Gm36136 MGI:MGI:5595295 +102639942 Gm21899 MGI:MGI:5434063 +102639943 Gm29586 MGI:MGI:5580292 +102639946 Gm36139 MGI:MGI:5595298 +102639948 Gm36140 MGI:MGI:5595299 +102639949 Gm36141 MGI:MGI:5595300 +102639950 LOC102639950 - +102639951 Gm36142 MGI:MGI:5595301 +102639953 Gm36144 MGI:MGI:5595303 +102639955 Gm36146 MGI:MGI:5595305 +102639956 Gm36147 MGI:MGI:5595306 +102639957 Gm12280 MGI:MGI:3652011 +102639958 LOC102639958 - +102639959 Gm36148 MGI:MGI:5595307 +102639960 Gm36149 MGI:MGI:5595308 +102639961 Gm36150 MGI:MGI:5595309 +102639962 Gm36151 MGI:MGI:5595310 +102639963 Gm36152 MGI:MGI:5595311 +102639964 Gm36153 MGI:MGI:5595312 +102639965 Gm36154 MGI:MGI:5595313 +102639967 Gm36156 MGI:MGI:5595315 +102639968 Gm36157 MGI:MGI:5595316 +102639969 Gm36158 MGI:MGI:5595317 +102639970 Gm28578 MGI:MGI:5579284 +102639971 Gm36159 MGI:MGI:5595318 +102639972 Gm10961 MGI:MGI:3779172 +102639974 LOC102639974 - +102639975 Gm36161 MGI:MGI:5595320 +102639977 Gm36163 MGI:MGI:5595322 +102639978 Gm36164 MGI:MGI:5595323 +102639979 LOC102639979 - +102639980 Gm36165 MGI:MGI:5595324 +102639982 LOC102639982 Ensembl:ENSMUSG00000109408 +102639983 Gm36166 MGI:MGI:5595325 +102639984 Gm36167 MGI:MGI:5595326 +102639985 Gm36168 MGI:MGI:5595327 +102639986 Gm36169 MGI:MGI:5595328 +102639987 LOC102639987 - +102639988 Gm36170 MGI:MGI:5595329 +102639989 Gm36171 MGI:MGI:5595330 +102639990 Gm28530 MGI:MGI:5579236 +102639991 Gm36172 MGI:MGI:5595331|Ensembl:ENSMUSG00000112758 +102639992 Gm36173 MGI:MGI:5595332|Ensembl:ENSMUSG00000112835 +102639993 Gm36174 MGI:MGI:5595333 +102639994 Gm36175 MGI:MGI:5595334 +102639995 Gm36176 MGI:MGI:5595335|Ensembl:ENSMUSG00000112653 +102639996 Gm36177 MGI:MGI:5595336 +102639997 Gm36178 MGI:MGI:5595337 +102639999 Gm36180 MGI:MGI:5595339 +102640000 Gm14578 MGI:MGI:3705739 +102640001 Gm29420 MGI:MGI:5580126 +102640002 Gm36181 MGI:MGI:5595340 +102640003 Gm36182 MGI:MGI:5595341 +102640005 Gm36183 MGI:MGI:5595342 +102640006 Gm36184 MGI:MGI:5595343 +102640008 Gm28800 MGI:MGI:5579506 +102640009 Gm36185 MGI:MGI:5595344 +102640010 Gm36186 MGI:MGI:5595345 +102640011 Gm36187 MGI:MGI:5595346 +102640012 Gm36188 MGI:MGI:5595347 +102640013 Gm36189 MGI:MGI:5595348 +102640014 Gm36190 MGI:MGI:5595349 +102640016 Gm36191 MGI:MGI:5595350 +102640018 Gm36193 MGI:MGI:5595352 +102640019 Gm36194 MGI:MGI:5595353 +102640020 Gm29152 MGI:MGI:5579858 +102640021 Gm36195 MGI:MGI:5595354 +102640022 Gm36196 MGI:MGI:5595355 +102640024 LOC102640024 - +102640025 Gm36198 MGI:MGI:5595357 +102640026 Gm16357 MGI:MGI:3840120 +102640029 Gm36199 MGI:MGI:5595358 +102640030 Gm36200 MGI:MGI:5595359 +102640031 Gm36201 MGI:MGI:5595360 +102640032 Gm36202 MGI:MGI:5595361 +102640033 Gm36203 MGI:MGI:5595362 +102640034 Gm36204 MGI:MGI:5595363 +102640035 LOC102640035 - +102640036 Gm36205 MGI:MGI:5595364 +102640037 Gm36206 MGI:MGI:5595365 +102640039 Gm36208 MGI:MGI:5595367 +102640040 LOC102640040 - +102640041 Gm36209 MGI:MGI:5595368 +102640042 LOC102640042 - +102640043 Gm36210 MGI:MGI:5595369|Ensembl:ENSMUSG00000110221|Vega:OTTMUSG00000061395 +102640044 Gm26550 MGI:MGI:5477044 +102640045 Gm36211 MGI:MGI:5595370 +102640046 Gm36212 MGI:MGI:5595371 +102640047 Gm36213 MGI:MGI:5595372 +102640048 Gm36214 MGI:MGI:5595373 +102640049 Gm28770 MGI:MGI:5579476 +102640050 Gm36215 MGI:MGI:5595374 +102640051 Gm29647 MGI:MGI:5580353 +102640052 Gm21855 MGI:MGI:5434019 +102640053 Gm28700 MGI:MGI:5579406 +102640054 Gm28741 MGI:MGI:5579447 +102640055 Gm21785 MGI:MGI:5433949 +102640056 Gm21792 MGI:MGI:5433956 +102640057 Gm36216 MGI:MGI:5595375 +102640059 LOC102640059 - +102640060 Gm36218 MGI:MGI:5595377 +102640061 Gm36219 MGI:MGI:5595378 +102640062 Gm12188 MGI:MGI:3651945 +102640063 Gm36220 MGI:MGI:5595379 +102640064 Gm36221 MGI:MGI:5595380 +102640065 Gm36222 MGI:MGI:5595381 +102640066 Gm36223 MGI:MGI:5595382 +102640067 LOC102640067 - +102640068 Gm36224 MGI:MGI:5595383 +102640069 Gm36225 MGI:MGI:5595384 +102640070 Gm36226 MGI:MGI:5595385 +102640071 Gm36227 MGI:MGI:5595386 +102640072 Gm36228 MGI:MGI:5595387 +102640073 Gm11820 MGI:MGI:3650049 +102640074 Gm36229 MGI:MGI:5595388 +102640076 Gm36231 MGI:MGI:5595390 +102640077 Gm36232 MGI:MGI:5595391 +102640078 Gm36233 MGI:MGI:5595392 +102640079 Gm36234 MGI:MGI:5595393 +102640080 Gm36235 MGI:MGI:5595394 +102640081 Gm36236 MGI:MGI:5595395 +102640082 Gm36237 MGI:MGI:5595396 +102640084 Gm36239 MGI:MGI:5595398 +102640085 Gm12956 MGI:MGI:3652227 +102640087 Gm36241 MGI:MGI:5595400 +102640089 Gm36243 MGI:MGI:5595402 +102640090 Gm36244 MGI:MGI:5595403 +102640092 Gm36245 MGI:MGI:5595404 +102640093 Gm36246 MGI:MGI:5595405 +102640094 Gm36247 MGI:MGI:5595406 +102640095 Gm15879 MGI:MGI:3802012 +102640097 Gm36249 MGI:MGI:5595408 +102640098 LOC102640098 - +102640100 Gm36251 MGI:MGI:5595410|Ensembl:ENSMUSG00000110996 +102640102 Gm36252 MGI:MGI:5595411 +102640103 LOC102640103 - +102640105 Gm36254 MGI:MGI:5595413 +102640106 Gm36255 MGI:MGI:5595414 +102640108 Gm36257 MGI:MGI:5595416 +102640109 Gm36258 MGI:MGI:5595417 +102640111 Gm36259 MGI:MGI:5595418 +102640113 Gm36260 MGI:MGI:5595419 +102640114 Gm36261 MGI:MGI:5595420 +102640115 Gm36262 MGI:MGI:5595421 +102640116 Gm36263 MGI:MGI:5595422 +102640117 Gm15201 MGI:MGI:3705207|Ensembl:ENSMUSG00000086034 +102640119 Gm36264 MGI:MGI:5595423 +102640122 Gm29428 MGI:MGI:5580134 +102640123 Gm14404 MGI:MGI:3649814 +102640124 Gm36266 MGI:MGI:5595425 +102640125 Gm36267 MGI:MGI:5595426 +102640126 Gm20445 MGI:MGI:5141910 +102640127 Gm36268 MGI:MGI:5595427 +102640128 Gm36269 MGI:MGI:5595428 +102640129 Gm36270 MGI:MGI:5595429 +102640130 Gm36271 MGI:MGI:5595430 +102640132 Gm36273 MGI:MGI:5595432 +102640133 LOC102640133 - +102640135 Gm36274 MGI:MGI:5595433 +102640137 Gm36276 MGI:MGI:5595435 +102640138 Gm36277 MGI:MGI:5595436 +102640139 LOC102640139 - +102640140 LOC102640140 - +102640141 Gm36278 MGI:MGI:5595437|Ensembl:ENSMUSG00000111769 +102640142 Gm36279 MGI:MGI:5595438 +102640143 Gm36280 MGI:MGI:5595439 +102640144 Gm17167 MGI:MGI:4937994 +102640145 Gm21286 MGI:MGI:5434641 +102640146 Gm36281 MGI:MGI:5595440 +102640147 Gm36282 MGI:MGI:5595441 +102640148 Gm36283 MGI:MGI:5595442|Ensembl:ENSMUSG00000112532 +102640149 Gm36284 MGI:MGI:5595443 +102640151 Gm36286 MGI:MGI:5595445 +102640152 Gm36287 MGI:MGI:5595446 +102640153 Gm36288 MGI:MGI:5595447 +102640154 Gm36289 MGI:MGI:5595448 +102640156 Gm36291 MGI:MGI:5595450 +102640157 Gm36292 MGI:MGI:5595451 +102640161 Gm28349 MGI:MGI:5579055 +102640163 Gm29480 MGI:MGI:5580186 +102640164 Gm36297 MGI:MGI:5595456 +102640165 Gm36298 MGI:MGI:5595457 +102640166 Gm36299 MGI:MGI:5595458 +102640167 Gm36300 MGI:MGI:5595459 +102640168 Gm36301 MGI:MGI:5595460 +102640169 Gm38524 MGI:MGI:5621409 +102640171 Gm38525 MGI:MGI:5621410 +102640172 LOC102640172 - +102640173 Gm28175 MGI:MGI:5578881 +102640174 Gm36303 MGI:MGI:5595462 +102640175 Gm36304 MGI:MGI:5595463 +102640176 Gm36305 MGI:MGI:5595464 +102640177 Gm36306 MGI:MGI:5595465 +102640178 Gm36307 MGI:MGI:5595466 +102640180 Gm36309 MGI:MGI:5595468 +102640181 Gm36310 MGI:MGI:5595469 +102640182 Gm36311 MGI:MGI:5595470 +102640183 Gm36312 MGI:MGI:5595471 +102640184 Gm36313 MGI:MGI:5595472 +102640186 Gm29201 MGI:MGI:5579907 +102640187 Gm36315 MGI:MGI:5595474 +102640188 Gm36316 MGI:MGI:5595475 +102640189 Gm36317 MGI:MGI:5595476 +102640190 Gm36318 MGI:MGI:5595477 +102640191 Gm36319 MGI:MGI:5595478 +102640192 Gm15510 MGI:MGI:3782958 +102640193 Gm36320 MGI:MGI:5595479 +102640195 Gm36322 MGI:MGI:5595481 +102640196 Gm36323 MGI:MGI:5595482 +102640197 Gm29131 MGI:MGI:5579837 +102640198 Gm29036 MGI:MGI:5579742 +102640199 LOC102640199 - +102640201 Gm36325 MGI:MGI:5595484 +102640202 Gm36326 MGI:MGI:5595485 +102640203 Gm36327 MGI:MGI:5595486 +102640204 Gm36328 MGI:MGI:5595487 +102640206 Gm36329 MGI:MGI:5595488 +102640207 Gm36330 MGI:MGI:5595489 +102640208 Gm36331 MGI:MGI:5595490 +102640210 Gm36333 MGI:MGI:5595492 +102640211 Gm36334 MGI:MGI:5595493 +102640212 Gm16214 MGI:MGI:3801724 +102640213 Gm36335 MGI:MGI:5595494 +102640214 Gm36336 MGI:MGI:5595495 +102640215 Gm36337 MGI:MGI:5595496 +102640216 Gm28874 MGI:MGI:5579580 +102640217 Gm36338 MGI:MGI:5595497 +102640218 LOC102640218 - +102640219 Gm36339 MGI:MGI:5595498 +102640220 Gm36340 MGI:MGI:5595499 +102640221 Gm36341 MGI:MGI:5595500 +102640225 Gm36345 MGI:MGI:5595504 +102640226 LOC102640226 - +102640227 Gm29255 MGI:MGI:5579961|Ensembl:ENSMUSG00000101425 +102640228 Gm28978 MGI:MGI:5579684 +102640229 Gm36346 MGI:MGI:5595505 +102640230 Gm36347 MGI:MGI:5595506 +102640231 Gm36348 MGI:MGI:5595507 +102640232 Gm36349 MGI:MGI:5595508 +102640233 Gm36350 MGI:MGI:5595509 +102640235 Gm36352 MGI:MGI:5595511 +102640237 Gm16838 MGI:MGI:4439762 +102640238 Gm36354 MGI:MGI:5595513 +102640239 Gm36355 MGI:MGI:5595514 +102640240 Gm10916 MGI:MGI:3779123 +102640241 LOC102640241 - +102640242 Gm36356 MGI:MGI:5595515 +102640243 Gm36357 MGI:MGI:5595516 +102640244 Gm36358 MGI:MGI:5595517 +102640245 Gm36359 MGI:MGI:5595518 +102640246 Gm36360 MGI:MGI:5595519 +102640249 Gm36363 MGI:MGI:5595522 +102640250 LOC102640250 - +102640252 Gm26511 MGI:MGI:5477005 +102640253 Gm36365 MGI:MGI:5595524 +102640254 Gm36366 MGI:MGI:5595525 +102640255 Gm36367 MGI:MGI:5595526 +102640256 Gm36368 MGI:MGI:5595527 +102640257 Gm36369 MGI:MGI:5595528 +102640259 Gm36371 MGI:MGI:5595530 +102640260 Gm36372 MGI:MGI:5595531 +102640261 Gm36373 MGI:MGI:5595532 +102640263 Gm36375 MGI:MGI:5595534 +102640264 Gm21895 MGI:MGI:5434059 +102640266 Gm36377 MGI:MGI:5595536 +102640267 Gm36378 MGI:MGI:5595537 +102640268 Gm2956 MGI:MGI:3781134 +102640269 Gm36380 MGI:MGI:5595539 +102640270 Gm36381 MGI:MGI:5595540 +102640271 Gm36382 MGI:MGI:5595541 +102640273 Gm36384 MGI:MGI:5595543 +102640274 Gm36385 MGI:MGI:5595544 +102640275 Gm36386 MGI:MGI:5595545 +102640276 Gm36387 MGI:MGI:5595546 +102640277 LOC102640277 - +102640278 Gm36388 MGI:MGI:5595547 +102640279 Gm36389 MGI:MGI:5595548 +102640280 Gm36390 MGI:MGI:5595549 +102640281 Gm36391 MGI:MGI:5595550 +102640282 Gm26885 MGI:MGI:5477379 +102640283 Gm36392 MGI:MGI:5595551 +102640284 Gm36393 MGI:MGI:5595552 +102640287 Gm36394 MGI:MGI:5595553 +102640288 Gm36395 MGI:MGI:5595554 +102640289 Gm36396 MGI:MGI:5595555 +102640291 Gm14630 MGI:MGI:3705376 +102640293 Gm36398 MGI:MGI:5595557 +102640295 LOC102640295 - +102640296 Gm12881 MGI:MGI:3651892 +102640298 Gm36401 MGI:MGI:5595560 +102640299 Gm36402 MGI:MGI:5595561 +102640300 Gm16083 MGI:MGI:3802163 +102640301 Gm38526 MGI:MGI:5621411 +102640302 Gm36403 MGI:MGI:5595562 +102640304 Gm36405 MGI:MGI:5595564 +102640305 Gm36406 MGI:MGI:5595565 +102640308 Gm38527 MGI:MGI:5621412 +102640309 Gm36408 MGI:MGI:5595567 +102640310 Gm36409 MGI:MGI:5595568 +102640311 Gm36410 MGI:MGI:5595569 +102640312 Gm36411 MGI:MGI:5595570 +102640313 Gm11713 MGI:MGI:3652139 +102640314 Gm36412 MGI:MGI:5595571 +102640316 Gm36413 MGI:MGI:5595572 +102640317 Gm36414 MGI:MGI:5595573 +102640318 Gm36415 MGI:MGI:5595574 +102640319 Gm36416 MGI:MGI:5595575 +102640320 Gm36417 MGI:MGI:5595576 +102640321 Gm36418 MGI:MGI:5595577 +102640322 Gm11973 MGI:MGI:3650058 +102640323 Gm36419 MGI:MGI:5595578 +102640325 LOC102640325 - +102640326 Gm36420 MGI:MGI:5595579 +102640327 LOC102640327 - +102640328 LOC102640328 - +102640330 Gm36422 MGI:MGI:5595581 +102640331 Gm36423 MGI:MGI:5595582 +102640333 Gm36424 MGI:MGI:5595583 +102640335 Gm36426 MGI:MGI:5595585 +102640336 Gm36427 MGI:MGI:5595586 +102640337 Gm36428 MGI:MGI:5595587 +102640338 Gm26782 MGI:MGI:5477276 +102640339 Gm36429 MGI:MGI:5595588 +102640340 Far2os1 MGI:MGI:4415003 +102640341 Gm36430 MGI:MGI:5595589 +102640342 Gm36431 MGI:MGI:5595590 +102640343 Gm11513 MGI:MGI:3649561 +102640344 LOC102640344 - +102640346 Gm28923 MGI:MGI:5579629 +102640348 Gm36434 MGI:MGI:5595593 +102640351 Gm36435 MGI:MGI:5595594|Ensembl:ENSMUSG00000111074 +102640352 Gm36436 MGI:MGI:5595595 +102640353 Gm36437 MGI:MGI:5595596 +102640354 Gm36438 MGI:MGI:5595597 +102640355 Gm36439 MGI:MGI:5595598 +102640356 Gm17059 MGI:MGI:4937886 +102640357 Gm36440 MGI:MGI:5595599 +102640359 LOC102640359 - +102640360 Gm12119 MGI:MGI:3652283 +102640361 Gm36441 MGI:MGI:5595600 +102640362 Gm36442 MGI:MGI:5595601 +102640363 Gm36443 MGI:MGI:5595602 +102640364 Gm28298 MGI:MGI:5579004 +102640365 Gm36444 MGI:MGI:5595603 +102640366 Gm29423 MGI:MGI:5580129 +102640367 Gm21881 MGI:MGI:5434045 +102640368 Gm15674 MGI:MGI:3783116|Ensembl:ENSMUSG00000087691 +102640369 Gm10138 MGI:MGI:3708522 +102640370 Gm14409 MGI:MGI:3649811 +102640371 Gm13837 MGI:MGI:3650972 +102640372 Gm36445 MGI:MGI:5595604 +102640373 Gm36446 MGI:MGI:5595605 +102640374 Gm36447 MGI:MGI:5595606 +102640375 Gm17116 MGI:MGI:4937943 +102640376 Gm36448 MGI:MGI:5595607 +102640377 Gm36449 MGI:MGI:5595608 +102640378 Gm36450 MGI:MGI:5595609 +102640379 Gm11716 MGI:MGI:3649215 +102640380 Gm36451 MGI:MGI:5595610 +102640382 Gm36453 MGI:MGI:5595612 +102640383 Gm36454 MGI:MGI:5595613 +102640384 Gm36455 MGI:MGI:5595614 +102640385 Hspe1-ps3 MGI:MGI:1935163 +102640386 Gm36456 MGI:MGI:5595615 +102640387 Gm36457 MGI:MGI:5595616 +102640388 Gm36458 MGI:MGI:5595617 +102640389 Gm36459 MGI:MGI:5595618 +102640390 Gm36460 MGI:MGI:5595619 +102640391 LOC102640391 - +102640392 Gm36461 MGI:MGI:5595620 +102640393 Gm36462 MGI:MGI:5595621 +102640394 Gm36463 MGI:MGI:5595622 +102640395 Gm36464 MGI:MGI:5595623 +102640398 Gm36466 MGI:MGI:5595625 +102640400 Gm36467 MGI:MGI:5595626 +102640401 Gm36468 MGI:MGI:5595627 +102640402 Gm28936 MGI:MGI:5579642 +102640404 Gm26861 MGI:MGI:5477355 +102640405 Gm36470 MGI:MGI:5595629 +102640407 Gm36472 MGI:MGI:5595631 +102640409 Gm36474 MGI:MGI:5595633 +102640410 Gm36475 MGI:MGI:5595634 +102640411 Gm36476 MGI:MGI:5595635 +102640412 Gm36477 MGI:MGI:5595636 +102640413 Gm36478 MGI:MGI:5595637 +102640414 Gm36479 MGI:MGI:5595638 +102640415 Gm36480 MGI:MGI:5595639 +102640416 Gm36481 MGI:MGI:5595640 +102640417 Gm36482 MGI:MGI:5595641 +102640418 Gm36483 MGI:MGI:5595642 +102640419 Gm16322 MGI:MGI:3826609 +102640421 Gm36485 MGI:MGI:5595644 +102640422 Gm36486 MGI:MGI:5595645 +102640423 Gm36487 MGI:MGI:5595646 +102640424 Gm36488 MGI:MGI:5595647 +102640426 Gm36490 MGI:MGI:5595649 +102640428 Gm36491 MGI:MGI:5595650 +102640429 Gm36492 MGI:MGI:5595651 +102640430 Gm36493 MGI:MGI:5595652 +102640432 Gm36495 MGI:MGI:5595654 +102640433 Gm36496 MGI:MGI:5595655 +102640435 Gm36498 MGI:MGI:5595657 +102640436 Gm14579 MGI:MGI:3705513 +102640437 LOC102640437 - +102640438 Gm36499 MGI:MGI:5595658 +102640439 Gm36500 MGI:MGI:5595659 +102640440 Gm28857 MGI:MGI:5579563 +102640441 Gm36501 MGI:MGI:5595660 +102640442 Gm36502 MGI:MGI:5595661 +102640443 Gm36503 MGI:MGI:5595662|Ensembl:ENSMUSG00000108025 +102640444 Gm36504 MGI:MGI:5595663 +102640445 Gm36505 MGI:MGI:5595664 +102640446 Gm36506 MGI:MGI:5595665 +102640447 Gm36507 MGI:MGI:5595666 +102640449 Tvp23bos MGI:MGI:3649886 +102640451 LOC102640451 - +102640452 Gm36509 MGI:MGI:5595668 +102640453 Gm36510 MGI:MGI:5595669 +102640456 Gm36513 MGI:MGI:5595672 +102640459 Gm36515 MGI:MGI:5595674 +102640460 Gm36516 MGI:MGI:5595675 +102640461 Gm36517 MGI:MGI:5595676 +102640462 Gm36518 MGI:MGI:5595677 +102640465 Gm36520 MGI:MGI:5595679 +102640466 Gm36521 MGI:MGI:5595680 +102640467 Gm36522 MGI:MGI:5595681 +102640468 LOC102640468 - +102640469 LOC102640469 - +102640470 Gm36523 MGI:MGI:5595682 +102640472 Gm36525 MGI:MGI:5595684 +102640474 Gm28742 MGI:MGI:5579448 +102640475 Gm29390 MGI:MGI:5580096 +102640476 Gm36527 MGI:MGI:5595686 +102640477 Gm14412 MGI:MGI:3652251 +102640478 Gm36528 MGI:MGI:5595687 +102640479 Gm36529 MGI:MGI:5595688|Ensembl:ENSMUSG00000113771 +102640482 Gm36531 MGI:MGI:5595690 +102640483 Gm36532 MGI:MGI:5595691 +102640484 Gm28651 MGI:MGI:5579357 +102640485 Gm36533 MGI:MGI:5595692 +102640486 Gm36534 MGI:MGI:5595693 +102640487 Gm36535 MGI:MGI:5595694 +102640488 Gm36536 MGI:MGI:5595695|Ensembl:ENSMUSG00000104021 +102640489 Gm15828 MGI:MGI:3802124 +102640490 LOC102640490 - +102640491 Gm36537 MGI:MGI:5595696 +102640492 Gm36538 MGI:MGI:5595697 +102640493 Gm36539 MGI:MGI:5595698 +102640494 Gm36540 MGI:MGI:5595699 +102640495 Gm17657 MGI:MGI:4937291 +102640496 Gm36541 MGI:MGI:5595700 +102640497 Gm36542 MGI:MGI:5595701 +102640498 Gm36543 MGI:MGI:5595702 +102640499 Gm36544 MGI:MGI:5595703 +102640500 LOC102640500 Ensembl:ENSMUSG00000095593 +102640502 Gm36546 MGI:MGI:5595705 +102640503 Gm36547 MGI:MGI:5595706 +102640504 Gm29360 MGI:MGI:5580066|Ensembl:ENSMUSG00000101740 +102640505 Gm29211 MGI:MGI:5579917 +102640506 Gm36548 MGI:MGI:5595707 +102640507 Gm36549 MGI:MGI:5595708 +102640509 Gm36550 MGI:MGI:5595709 +102640510 Gm36551 MGI:MGI:5595710 +102640511 Gm36552 MGI:MGI:5595711 +102640512 Gm36553 MGI:MGI:5595712 +102640513 Gm36554 MGI:MGI:5595713 +102640514 Gm36555 MGI:MGI:5595714 +102640515 Gm36556 MGI:MGI:5595715 +102640517 Gm36558 MGI:MGI:5595717 +102640518 Gm36559 MGI:MGI:5595718 +102640519 Gm36560 MGI:MGI:5595719 +102640520 LOC102640520 - +102640521 Gm36561 MGI:MGI:5595720 +102640522 Gm36562 MGI:MGI:5595721 +102640523 Gm36563 MGI:MGI:5595722 +102640524 Gm36564 MGI:MGI:5595723 +102640525 Gm36565 MGI:MGI:5595724 +102640526 LOC102640526 - +102640527 Gm36566 MGI:MGI:5595725 +102640528 Gm36567 MGI:MGI:5595726 +102640529 Gm36568 MGI:MGI:5595727 +102640530 Gm36569 MGI:MGI:5595728|Ensembl:ENSMUSG00000102191 +102640531 Gm36570 MGI:MGI:5595729 +102640532 Gm14652 MGI:MGI:3642895 +102640533 Gm36571 MGI:MGI:5595730 +102640534 Gm36572 MGI:MGI:5595731 +102640535 Gm29386 MGI:MGI:5580092|Ensembl:ENSMUSG00000101626 +102640536 Gm36573 MGI:MGI:5595732 +102640537 Gm36574 MGI:MGI:5595733 +102640542 Gm36579 MGI:MGI:5595738 +102640544 Gm36581 MGI:MGI:5595740 +102640545 Gm36582 MGI:MGI:5595741 +102640546 Gm36583 MGI:MGI:5595742 +102640547 Gm36584 MGI:MGI:5595743 +102640549 Gm36585 MGI:MGI:5595744 +102640550 Gm36586 MGI:MGI:5595745 +102640551 Gm36587 MGI:MGI:5595746 +102640553 Gm36589 MGI:MGI:5595748 +102640554 Gm36590 MGI:MGI:5595749 +102640555 Gm36591 MGI:MGI:5595750 +102640556 Gm11009 MGI:MGI:3779227 +102640557 Gm36592 MGI:MGI:5595751 +102640559 Gm36594 MGI:MGI:5595753 +102640560 Gm36595 MGI:MGI:5595754 +102640561 Gm36596 MGI:MGI:5595755 +102640562 BB218582 MGI:MGI:2139448|Ensembl:ENSMUSG00000085218 +102640563 Gm36597 MGI:MGI:5595756 +102640564 Gm36598 MGI:MGI:5595757 +102640565 Gm36599 MGI:MGI:5595758 +102640566 Gm36600 MGI:MGI:5595759 +102640567 Gm36601 MGI:MGI:5595760 +102640568 Gm36602 MGI:MGI:5595761 +102640569 Gm36603 MGI:MGI:5595762 +102640570 Gm36604 MGI:MGI:5595763 +102640571 Gm36605 MGI:MGI:5595764 +102640572 Gm29391 MGI:MGI:5580097 +102640574 Gm36606 MGI:MGI:5595765 +102640575 LOC102640575 - +102640576 Gm36607 MGI:MGI:5595766 +102640577 Gm28515 MGI:MGI:5579221 +102640578 Gm36608 MGI:MGI:5595767 +102640580 Gm36610 MGI:MGI:5595769 +102640581 Gm36611 MGI:MGI:5595770 +102640582 Gm36612 MGI:MGI:5595771 +102640583 Gm36613 MGI:MGI:5595772 +102640584 Gm36614 MGI:MGI:5595773 +102640585 Gm36615 MGI:MGI:5595774 +102640586 LOC102640586 - +102640587 Gm36616 MGI:MGI:5595775 +102640588 Gm11769 MGI:MGI:3702101 +102640589 Gm36617 MGI:MGI:5595776 +102640590 Gm36618 MGI:MGI:5595777 +102640591 Gm36619 MGI:MGI:5595778 +102640592 Gm36620 MGI:MGI:5595779 +102640593 Gm36621 MGI:MGI:5595780 +102640594 Gm28710 MGI:MGI:5579416 +102640595 Gm36622 MGI:MGI:5595781 +102640596 Gm36623 MGI:MGI:5595782 +102640597 Gm29571 MGI:MGI:5580277|Ensembl:ENSMUSG00000101537 +102640601 Gm36627 MGI:MGI:5595786 +102640603 Gm36628 MGI:MGI:5595787 +102640604 Gm36629 MGI:MGI:5595788 +102640606 Gm36631 MGI:MGI:5595790 +102640608 Gm36633 MGI:MGI:5595792|Ensembl:ENSMUSG00000108480 +102640609 Gm36634 MGI:MGI:5595793 +102640611 Gm21896 MGI:MGI:5434060 +102640612 Gm36635 MGI:MGI:5595794 +102640614 Gm29212 MGI:MGI:5579918 +102640615 Gm10357 MGI:MGI:3641865 +102640616 Gm28133 MGI:MGI:5578839 +102640618 Gm36638 MGI:MGI:5595797 +102640619 LOC102640619 - +102640620 Gm36639 MGI:MGI:5595798 +102640621 Gm36640 MGI:MGI:5595799 +102640622 Gm36641 MGI:MGI:5595800 +102640623 Gm36642 MGI:MGI:5595801 +102640624 LOC102640624 - +102640626 Gm36644 MGI:MGI:5595803 +102640630 Gm36648 MGI:MGI:5595807 +102640631 Gm36649 MGI:MGI:5595808 +102640633 Gm36650 MGI:MGI:5595809 +102640634 Gm36651 MGI:MGI:5595810 +102640635 Gm26615 MGI:MGI:5477109 +102640636 Gm36652 MGI:MGI:5595811 +102640637 Gm36653 MGI:MGI:5595812 +102640638 Gm36654 MGI:MGI:5595813 +102640639 Gm36655 MGI:MGI:5595814 +102640640 Gm36656 MGI:MGI:5595815 +102640642 Astx3 MGI:MGI:3705273 +102640643 Gm36658 MGI:MGI:5595817 +102640645 Gm36660 MGI:MGI:5595819 +102640646 Gm36661 MGI:MGI:5595820 +102640648 Gm36663 MGI:MGI:5595822 +102640650 Gm29505 MGI:MGI:5580211 +102640651 Gm36665 MGI:MGI:5595824 +102640653 Gm36667 MGI:MGI:5595826 +102640655 Gm36669 MGI:MGI:5595828|Ensembl:ENSMUSG00000107022 +102640656 Gm36670 MGI:MGI:5595829|Ensembl:ENSMUSG00000109696 +102640657 Gm36671 MGI:MGI:5595830 +102640658 Gm36672 MGI:MGI:5595831 +102640659 Gm36673 MGI:MGI:5595832 +102640660 Gm36674 MGI:MGI:5595833 +102640661 Gm36675 MGI:MGI:5595834 +102640662 Gm12343 MGI:MGI:3649817 +102640663 Gm36677 MGI:MGI:5595836 +102640664 Gm36678 MGI:MGI:5595837 +102640665 Gm36679 MGI:MGI:5595838 +102640666 Gm36680 MGI:MGI:5595839 +102640667 Gm36681 MGI:MGI:5595840 +102640669 Gm36683 MGI:MGI:5595842 +102640670 Gm36684 MGI:MGI:5595843 +102640671 Gm36685 MGI:MGI:5595844 +102640672 Gm36686 MGI:MGI:5595845 +102640673 LOC102640673 - +102640674 Gm36687 MGI:MGI:5595846 +102640676 Gm36689 MGI:MGI:5595848 +102640677 Gm36690 MGI:MGI:5595849 +102640678 Gm36691 MGI:MGI:5595850 +102640681 Gm36693 MGI:MGI:5595852 +102640682 Gm36694 MGI:MGI:5595853 +102640683 Gm36695 MGI:MGI:5595854 +102640684 Gm36696 MGI:MGI:5595855 +102640688 Gm29498 MGI:MGI:5580204 +102640691 Gm28678 MGI:MGI:5579384 +102640692 Gm21919 MGI:MGI:5434083 +102640693 LOC102640693 - +102640694 Gm36702 MGI:MGI:5595861 +102640695 Gm28181 MGI:MGI:5578887 +102640696 LOC102640696 - +102640697 Gm36703 MGI:MGI:5595862 +102640699 Gm36704 MGI:MGI:5595863 +102640700 Gm36705 MGI:MGI:5595864 +102640701 Gm22498 MGI:MGI:5452275 +102640705 Gm36709 MGI:MGI:5595868 +102640706 Gm36710 MGI:MGI:5595869 +102640707 Gm15793 MGI:MGI:3783235 +102640708 Gm26980 MGI:MGI:5504095 +102640710 Gm36712 MGI:MGI:5595871 +102640712 Gm36714 MGI:MGI:5595873 +102640713 Gm36715 MGI:MGI:5595874 +102640715 Gm38528 MGI:MGI:5621413 +102640716 Gm36717 MGI:MGI:5595876 +102640717 Gm36718 MGI:MGI:5595877 +102640718 Gm36719 MGI:MGI:5595878 +102640719 Gm36720 MGI:MGI:5595879 +102640720 Gm12121 MGI:MGI:3651988 +102640721 Gm36721 MGI:MGI:5595880 +102640722 Gm36722 MGI:MGI:5595881 +102640723 Gm36723 MGI:MGI:5595882 +102640724 Gm36724 MGI:MGI:5595883 +102640726 Gm36726 MGI:MGI:5595885 +102640728 Gm36728 MGI:MGI:5595887 +102640729 Gm21845 MGI:MGI:5434009 +102640731 Gm36730 MGI:MGI:5595889 +102640732 Gm29121 MGI:MGI:5579827 +102640733 Gm28204 MGI:MGI:5578910 +102640735 Gm36732 MGI:MGI:5595891 +102640737 Gm36734 MGI:MGI:5595893 +102640739 Gm36735 MGI:MGI:5595894 +102640740 Gm36736 MGI:MGI:5595895 +102640741 Gm36737 MGI:MGI:5595896 +102640742 Gm36738 MGI:MGI:5595897 +102640743 Gm36739 MGI:MGI:5595898 +102640744 Gm36740 MGI:MGI:5595899 +102640745 Gm36741 MGI:MGI:5595900 +102640746 Gm36742 MGI:MGI:5595901 +102640747 Gm15423 MGI:MGI:3705184 +102640748 Gm36743 MGI:MGI:5595902 +102640749 Gm13398 MGI:MGI:3652315 +102640750 Gm36744 MGI:MGI:5595903 +102640751 Gm36745 MGI:MGI:5595904 +102640752 Gm16758 MGI:MGI:4439682 +102640753 Gm36746 MGI:MGI:5595905 +102640754 LOC102640754 - +102640755 Gm36747 MGI:MGI:5595906 +102640756 Gm36748 MGI:MGI:5595907 +102640757 Gm36749 MGI:MGI:5595908 +102640758 Gm36750 MGI:MGI:5595909 +102640759 Gm36751 MGI:MGI:5595910 +102640760 Gm36752 MGI:MGI:5595911 +102640761 Gm36753 MGI:MGI:5595912 +102640762 Gm36754 MGI:MGI:5595913 +102640764 Gm36756 MGI:MGI:5595915 +102640765 Gm36757 MGI:MGI:5595916 +102640766 Gm28136 MGI:MGI:5578842 +102640767 Gm29424 MGI:MGI:5580130 +102640768 Gm36758 MGI:MGI:5595917 +102640770 Gm36760 MGI:MGI:5595919 +102640771 LOC102640771 Ensembl:ENSMUSG00000086706 +102640772 LOC102640772 Ensembl:ENSMUSG00000100594 +102640773 Gm9901 MGI:MGI:3708797 +102640774 Gm36761 MGI:MGI:5595920 +102640775 LOC102640775 - +102640776 Gm36762 MGI:MGI:5595921 +102640777 Gm36763 MGI:MGI:5595922 +102640778 Cdrt4os2 MGI:MGI:3705321 +102640779 LOC102640779 - +102640780 Gm36764 MGI:MGI:5595923 +102640781 Gm36765 MGI:MGI:5595924 +102640782 Gm36766 MGI:MGI:5595925 +102640783 Gm36767 MGI:MGI:5595926 +102640784 Gm36768 MGI:MGI:5595927 +102640785 Gm36769 MGI:MGI:5595928 +102640788 Gm36771 MGI:MGI:5595930 +102640789 Gm36772 MGI:MGI:5595931 +102640791 Gm36774 MGI:MGI:5595933 +102640793 Gm36776 MGI:MGI:5595935 +102640795 Gm36778 MGI:MGI:5595937 +102640797 Gm28938 MGI:MGI:5579644|Ensembl:ENSMUSG00000099537 +102640800 Gm36782 MGI:MGI:5595941 +102640801 Gm36783 MGI:MGI:5595942 +102640802 Gm36784 MGI:MGI:5595943 +102640803 Gm36785 MGI:MGI:5595944 +102640804 Gm21818 MGI:MGI:5433982|Ensembl:ENSMUSG00000095653 +102640806 Gm36787 MGI:MGI:5595946 +102640807 Gm36788 MGI:MGI:5595947 +102640808 Gm26653 MGI:MGI:5477147 +102640809 Gm36789 MGI:MGI:5595948 +102640810 Gm36790 MGI:MGI:5595949 +102640811 LOC102640811 - +102640812 Gm36791 MGI:MGI:5595950 +102640814 Gm28497 MGI:MGI:5579203 +102640815 Gm36793 MGI:MGI:5595952|Ensembl:ENSMUSG00000106255 +102640816 Gm36794 MGI:MGI:5595953 +102640817 Gm36795 MGI:MGI:5595954 +102640818 Gm36796 MGI:MGI:5595955 +102640819 Gm36797 MGI:MGI:5595956 +102640820 Gm36798 MGI:MGI:5595957 +102640821 Gm36799 MGI:MGI:5595958|Ensembl:ENSMUSG00000110823 +102640822 Nr6a1os MGI:MGI:3649430 +102640823 Gm26510 MGI:MGI:5477004 +102640824 Gm36801 MGI:MGI:5595960 +102640825 Gm13715 MGI:MGI:3650277|Ensembl:ENSMUSG00000085025 +102640826 Gm36802 MGI:MGI:5595961 +102640827 Gm36803 MGI:MGI:5595962 +102640828 Gm36804 MGI:MGI:5595963 +102640829 Gm13257 MGI:MGI:3651057 +102640831 Gm36806 MGI:MGI:5595965 +102640832 Gm26947 MGI:MGI:5504062 +102640833 Gm36807 MGI:MGI:5595966 +102640834 Gm36808 MGI:MGI:5595967 +102640835 Gm36809 MGI:MGI:5595968 +102640837 Gm36811 MGI:MGI:5595970 +102640838 LOC102640838 - +102640839 Gm12963 MGI:MGI:3651569 +102640842 Gm29393 MGI:MGI:5580099|Ensembl:ENSMUSG00000101533 +102640843 Gm36814 MGI:MGI:5595973 +102640845 Gm26994 MGI:MGI:5504109|Ensembl:ENSMUSG00000098075 +102640846 Gm36816 MGI:MGI:5595975 +102640847 Gm17079 MGI:MGI:4937906 +102640848 Gm36817 MGI:MGI:5595976 +102640849 Gm36818 MGI:MGI:5595977 +102640850 Gm11788 MGI:MGI:3649943 +102640851 Gm36819 MGI:MGI:5595978 +102640852 Gm36820 MGI:MGI:5595979 +102640853 Gm36821 MGI:MGI:5595980 +102640854 Gm36822 MGI:MGI:5595981 +102640855 Gm36823 MGI:MGI:5595982 +102640856 Gm36824 MGI:MGI:5595983 +102640858 Gm36826 MGI:MGI:5595985 +102640859 Gm36827 MGI:MGI:5595986 +102640862 Gm36829 MGI:MGI:5595988 +102640863 Gm36830 MGI:MGI:5595989 +102640864 LOC102640864 - +102640866 Gm36831 MGI:MGI:5595990 +102640870 Gm36834 MGI:MGI:5595993 +102640871 Gm21753 MGI:MGI:5433917 +102640872 Gm29280 MGI:MGI:5579986 +102640873 Gm36835 MGI:MGI:5595994 +102640875 Gm28736 MGI:MGI:5579442 +102640878 Gm21910 MGI:MGI:5434074 +102640879 Gm36839 MGI:MGI:5595998 +102640880 Gm28220 MGI:MGI:5578926|Ensembl:ENSMUSG00000101961 +102640881 Gm36840 MGI:MGI:5595999 +102640882 LOC102640882 - +102640883 Gm36841 MGI:MGI:5596000 +102640885 Gm36843 MGI:MGI:5596002 +102640886 Gm36844 MGI:MGI:5596003 +102640887 Gm36845 MGI:MGI:5596004 +102640889 Gm36847 MGI:MGI:5596006 +102640890 Gm36848 MGI:MGI:5596007 +102640891 Gm36849 MGI:MGI:5596008 +102640893 Gm36851 MGI:MGI:5596010 +102640894 Gm16193 MGI:MGI:3802025 +102640895 Gm36852 MGI:MGI:5596011 +102640897 Gm36853 MGI:MGI:5596012 +102640899 Gm36855 MGI:MGI:5596014 +102640900 Gm28231 MGI:MGI:5578937|Ensembl:ENSMUSG00000100782 +102640901 Gm36856 MGI:MGI:5596015 +102640902 Gm11844 MGI:MGI:3651040 +102640903 Gm36857 MGI:MGI:5596016 +102640904 Gm36858 MGI:MGI:5596017 +102640905 Gm36859 MGI:MGI:5596018 +102640906 Gm13049 MGI:MGI:3650887 +102640908 Gm36860 MGI:MGI:5596019 +102640909 Gm36861 MGI:MGI:5596020 +102640910 Gm36862 MGI:MGI:5596021 +102640912 Gm36863 MGI:MGI:5596022 +102640913 Gm36864 MGI:MGI:5596023|Ensembl:ENSMUSG00000108622 +102640914 Gm36865 MGI:MGI:5596024 +102640915 Gm36866 MGI:MGI:5596025 +102640916 Gm36867 MGI:MGI:5596026 +102640917 Gm29493 MGI:MGI:5580199 +102640919 Gm25279 MGI:MGI:5455056 +102640920 Pvrig MGI:MGI:5596028|Ensembl:ENSMUSG00000109713|Vega:OTTMUSG00000060688 +102640921 LOC102640921 - +102640923 LOC102640923 - +102640924 Gm36871 MGI:MGI:5596030 +102640925 Gm36872 MGI:MGI:5596031 +102640926 Gm36873 MGI:MGI:5596032 +102640927 Gm36874 MGI:MGI:5596033 +102640928 Gm36875 MGI:MGI:5596034 +102640929 Gm36876 MGI:MGI:5596035 +102640930 Gm36877 MGI:MGI:5596036 +102640931 Gm36878 MGI:MGI:5596037 +102640932 Gm36879 MGI:MGI:5596038 +102640933 Gm42411 MGI:MGI:5632317 +102640934 Gm36880 MGI:MGI:5596039 +102640936 Gm36882 MGI:MGI:5596041 +102640937 Gm36883 MGI:MGI:5596042 +102640938 Gm36884 MGI:MGI:5596043 +102640939 Gm36885 MGI:MGI:5596044 +102640940 Gm36886 MGI:MGI:5596045 +102640941 Gm36887 MGI:MGI:5596046 +102640942 Gm36888 MGI:MGI:5596047 +102640945 Gm36891 MGI:MGI:5596050 +102640946 LOC102640946 - +102640947 Gm36892 MGI:MGI:5596051 +102640948 Gm36893 MGI:MGI:5596052 +102640949 Gm36894 MGI:MGI:5596053 +102640950 Gm28890 MGI:MGI:5579596 +102640951 Gm15614 MGI:MGI:3783059|Ensembl:ENSMUSG00000085234 +102640952 Gm15627 MGI:MGI:3783071 +102640953 Gm36895 MGI:MGI:5596054 +102640954 Gm36896 MGI:MGI:5596055 +102640955 LOC102640955 - +102640956 Gm36897 MGI:MGI:5596056 +102640957 LOC102640957 - +102640959 Gm36899 MGI:MGI:5596058 +102640960 Gm36900 MGI:MGI:5596059 +102640961 Gm36901 MGI:MGI:5596060 +102640962 Gm16348 MGI:MGI:3840113 +102640964 Gm36902 MGI:MGI:5596061 +102640965 Gm36903 MGI:MGI:5596062 +102640966 Gm36904 MGI:MGI:5596063 +102640967 Gm36905 MGI:MGI:5596064 +102640968 Gm36906 MGI:MGI:5596065 +102640969 Gm29603 MGI:MGI:5580309 +102640970 Gm36907 MGI:MGI:5596066 +102640971 CJ186046Rik MGI:MGI:5319478 +102640972 Gm36908 MGI:MGI:5596067 +102640973 Gm36909 MGI:MGI:5596068 +102640975 Gm36910 MGI:MGI:5596069 +102640976 Gm36911 MGI:MGI:5596070 +102640977 LOC102640977 - +102640979 Gm20610 MGI:MGI:5313057 +102640980 Gm36913 MGI:MGI:5596072 +102640981 Gm36914 MGI:MGI:5596073 +102640983 Gm36915 MGI:MGI:5596074 +102640984 Gm28076 MGI:MGI:5578782 +102640985 LOC102640985 - +102640986 Gm36916 MGI:MGI:5596075 +102640987 Gm36917 MGI:MGI:5596076 +102640988 Gm24595 MGI:MGI:5454372 +102640989 Gm36918 MGI:MGI:5596077 +102640990 Gm28207 MGI:MGI:5578913|Ensembl:ENSMUSG00000100167 +102640991 Gm16984 MGI:MGI:4439908 +102640992 Gm21838 MGI:MGI:5434002 +102640994 Gm36920 MGI:MGI:5596079 +102640995 Gm36921 MGI:MGI:5596080 +102640996 Gm36922 MGI:MGI:5596081 +102640998 Gm36924 MGI:MGI:5596083 +102641000 Gm36926 MGI:MGI:5596085 +102641004 LOC102641004 - +102641007 LOC102641007 - +102641008 LOC102641008 - +102641009 LOC102641009 - +102641016 LOC102641016 - +102641018 LOC102641018 - +102641027 LOC102641027 - +102641028 LOC102641028 - +102641029 LOC102641029 - +102641031 LOC102641031 - +102641034 LOC102641034 - +102641037 LOC102641037 - +102641038 LOC102641038 - +102641048 LOC102641048 - +102641050 LOC102641050 - +102641052 Gm13093 MGI:MGI:3650866 +102641053 LOC102641053 - +102641055 LOC102641055 - +102641064 LOC102641064 - +102641065 LOC102641065 - +102641066 LOC102641066 - +102641068 Gm38529 MGI:MGI:5621414 +102641070 Gm38530 MGI:MGI:5621415 +102641078 Gm38531 MGI:MGI:5621416 +102641079 LOC102641079 - +102641081 Gm15704 MGI:MGI:3783144 +102641086 LOC102641086 - +102641091 LOC102641091 - +102641092 LOC102641092 - +102641095 LOC102641095 - +102641098 LOC102641098 - +102641100 LOC102641100 - +102641103 Gm38532 MGI:MGI:5621417 +102641104 Gm38533 MGI:MGI:5621418 +102641105 Gm38534 MGI:MGI:5621419 +102641118 Gm38535 MGI:MGI:5621420 +102641120 Gm29483 MGI:MGI:5580189 +102641146 Gm38536 MGI:MGI:5621421 +102641152 Gm38537 MGI:MGI:5621422 +102641157 Gm38538 MGI:MGI:5621423 +102641161 LOC102641161 - +102641163 Gm38165 MGI:MGI:5611393 +102641173 LOC102641173 - +102641179 Gm38539 MGI:MGI:5621424 +102641188 Gm38540 MGI:MGI:5621425 +102641202 Gm38541 MGI:MGI:5621426 +102641211 LOC102641211 - +102641229 LOC102641229 - +102641233 Gm38542 MGI:MGI:5621427 +102641235 Cbx3-ps3 MGI:MGI:1890540 +102641236 Gm38543 MGI:MGI:5621428 +102641244 Gm27239 MGI:MGI:5521082 +102641247 Gm12339 MGI:MGI:3650628 +102641256 Gm38544 MGI:MGI:5621429 +102641261 LOC102641261 - +102641270 Gm38545 MGI:MGI:5621430 +102641276 LOC102641276 - +102641286 Gm14244 MGI:MGI:3651251|Ensembl:ENSMUSG00000087162 +102641287 Gm38546 MGI:MGI:5621431 +102641289 LOC102641289 - +102641297 LOC102641297 - +102641305 LOC102641305 - +102641308 Gm38547 MGI:MGI:5621432 +102641315 LOC102641315 - +102641332 LOC102641332 - +102641335 Gm38548 MGI:MGI:5621433 +102641341 LOC102641341 - +102641346 Gm38549 MGI:MGI:5621434 +102641347 LOC102641347 - +102641351 LOC102641351 - +102641355 Gm38550 MGI:MGI:5621435 +102641363 Gm38551 MGI:MGI:5621436 +102641369 Gm38552 MGI:MGI:5621437 +102641372 Gm38553 MGI:MGI:5621438 +102641383 LOC102641383 - +102641385 Gm38554 MGI:MGI:5621439 +102641396 Gm38555 MGI:MGI:5621440 +102641406 Gm38556 MGI:MGI:5621441 +102641408 Gm38557 MGI:MGI:5621442 +102641430 Gm38558 MGI:MGI:5621443 +102641432 Gm38559 MGI:MGI:5621444 +102641436 LOC102641436 - +102641455 LOC102641455 - +102641463 Gm17175 MGI:MGI:4938002 +102641464 LOC102641464 - +102641467 Gm20684 MGI:MGI:5313131 +102641476 Gm38560 MGI:MGI:5621445 +102641483 LOC102641483 - +102641497 LOC102641497 - +102641498 Gm37915 MGI:MGI:5611143 +102641500 LOC102641500 - +102641509 Gm16299 MGI:MGI:3826539|Ensembl:ENSMUSG00000089679 +102641516 Gm38561 MGI:MGI:5621446 +102641523 Gm37108 MGI:MGI:5610336 +102641529 Gm38562 MGI:MGI:5621447 +102641539 Gm13596 MGI:MGI:3651140 +102641541 LOC102641541 - +102641552 Gm38563 MGI:MGI:5621448 +102641557 Gm38564 MGI:MGI:5621449 +102641600 LOC102641600 - +102641609 Gm38565 MGI:MGI:5621450 +102641610 Gm38566 MGI:MGI:5621451 +102641613 LOC102641613 - +102641617 Gm27151 MGI:MGI:5520994 +102641619 LOC102641619 - +102641621 LOC102641621 - +102641625 Gm15802 MGI:MGI:3801799 +102641637 Gm38567 MGI:MGI:5621452 +102641642 Gm38568 MGI:MGI:5621453 +102641654 LOC102641654 - +102641657 LOC102641657 - +102641661 Gm38569 MGI:MGI:5621454 +102641663 LOC102641663 - +102641666 LOC102641666 - +102641678 LOC102641678 - +102641700 Gm38570 MGI:MGI:5621455 +102641704 Gm11690 MGI:MGI:3652329 +102641705 LOC102641705 - +102641725 Gm38571 MGI:MGI:5621456 +102641740 Gm38572 MGI:MGI:5621457 +102641749 Gm38573 MGI:MGI:5621458 +102641751 LOC102641751 - +102641752 Gm38574 MGI:MGI:5621459 +102641761 LOC102641761 - +102641779 Gm15239 MGI:MGI:3705189 +102641783 Gm38575 MGI:MGI:5621460 +102641800 Gm38576 MGI:MGI:5621461 +102641805 LOC102641805 - +102641809 LOC102641809 - +102641825 Gm38577 MGI:MGI:5621462 +102641829 Gm38578 MGI:MGI:5621463 +102641836 Gm38579 MGI:MGI:5621464 +102641840 LOC102641840 - +102641841 Gm38580 MGI:MGI:5621465 +102641855 Gm38581 MGI:MGI:5621466 +102641859 LOC102641859 - +102641860 Gm26578 MGI:MGI:5477072 +102641872 LOC102641872 - +102641876 Gm38582 MGI:MGI:5621467 +102641880 Mapk6-ps1 MGI:MGI:2181531 +102641901 Gm38583 MGI:MGI:5621468 +102641916 LOC102641916 - +102641929 Gm38584 MGI:MGI:5621469 +102641931 Gm38585 MGI:MGI:5621470 +102641936 LOC102641936 - +102641941 Gm38586 MGI:MGI:5621471 +102641942 LOC102641942 - +102641946 AA692955 MGI:MGI:3034750 +102641949 LOC102641949 - +102641964 Gm38587 MGI:MGI:5621472 +102641966 Gm38588 MGI:MGI:5621473 +102641980 Gm15860 MGI:MGI:3801778 +102641986 Teyorf1 MGI:MGI:5581504 +102641989 Gm38589 MGI:MGI:5621474 +102641995 Gm38590 MGI:MGI:5621475 +102642006 Gm38591 MGI:MGI:5621476 +102642011 Gm38592 MGI:MGI:5621477 +102642016 Prssly MGI:MGI:5581670 +102642034 LOC102642034 - +102642038 LOC102642038 - +102642041 Gm38593 MGI:MGI:5621478 +102642043 LOC102642043 - +102642065 Gm38594 MGI:MGI:5621479 +102642066 Gm38595 MGI:MGI:5621480 +102642067 Gm38596 MGI:MGI:5621481 +102642088 LOC102642088 - +102642117 LOC102642117 - +102642137 LOC102642137 - +102642146 Gm38597 MGI:MGI:5621482 +102642160 Gm22496 MGI:MGI:5452273 +102642162 Gm38326 MGI:MGI:5611554|Ensembl:ENSMUSG00000103587 +102642191 LOC102642191 - +102642194 Gm38598 MGI:MGI:5621483 +102642196 Gm38599 MGI:MGI:5621484 +102642197 LOC102642197 - +102642202 Gm15511 MGI:MGI:3782959|Ensembl:ENSMUSG00000086648 +102642210 Gm38600 MGI:MGI:5621485 +102642215 LOC102642215 - +102642216 LOC102642216 - +102642244 Gm38601 MGI:MGI:5621486 +102642252 LOC102642252 - +102642281 Gm38602 MGI:MGI:5621487 +102642295 LOC102642295 - +102642297 Gm38603 MGI:MGI:5621488 +102642321 Gm38604 MGI:MGI:5621489 +102642339 Gm38605 MGI:MGI:5621490 +102642358 Gm38606 MGI:MGI:5621491 +102642374 Gm38607 MGI:MGI:5621492 +102642381 Gm38608 MGI:MGI:5621493 +102642386 LOC102642386 Ensembl:ENSMUSG00000090744|Vega:OTTMUSG00000035315 +102642389 Gm38609 MGI:MGI:5621494 +102642392 Gm38610 MGI:MGI:5621495 +102642414 Platr3 MGI:MGI:3651129 +102642420 LOC102642420 - +102642435 LOC102642435 - +102642443 Gm26717 MGI:MGI:5477211 +102642451 Gm38611 MGI:MGI:5621496 +102642459 Gm14229 MGI:MGI:3651930 +102642476 LOC102642476 - +102642477 LOC102642477 - +102642489 Gm38612 MGI:MGI:5621497 +102642507 LOC102642507 - +102642508 Gm38613 MGI:MGI:5621498 +102642514 LOC102642514 - +102642523 LOC102642523 - +102642544 Gm38614 MGI:MGI:5621499 +102642556 Gm38615 MGI:MGI:5621500 +102642578 LOC102642578 - +102642581 Gm38616 MGI:MGI:5621501 +102642602 LOC102642602 - +102642605 Gm38617 MGI:MGI:5621502 +102642612 Gm38618 MGI:MGI:5621503 +102642616 Gm38619 MGI:MGI:5621504 +102642619 LOC102642619 - +102642625 Gm38620 MGI:MGI:5621505 +102642633 Gm38621 MGI:MGI:5621506 +102642637 LOC102642637 - +102642641 LOC102642641 - +102642644 Gm38622 MGI:MGI:5621507 +102642652 Gm38623 MGI:MGI:5621508 +102642675 Gm38624 MGI:MGI:5621509 +102642677 Gm38625 MGI:MGI:5621510 +102642689 LOC102642689 - +102642702 Gm38626 MGI:MGI:5621511 +102642720 Gm38627 MGI:MGI:5621512 +102642726 Gm38628 MGI:MGI:5621513 +102642737 Gm38629 MGI:MGI:5621514 +102642752 LOC102642752 - +102642755 Gm38630 MGI:MGI:5621515 +102642773 Gm38631 MGI:MGI:5621516 +102642778 Gm38632 MGI:MGI:5621517 +102642783 Gm38633 MGI:MGI:5621518 +102642791 Gm38634 MGI:MGI:5621519 +102642793 Gm38635 MGI:MGI:5621520 +102642800 Gm38636 MGI:MGI:5621521 +102642808 LOC102642808 - +102642815 Gm38637 MGI:MGI:5621522 +102642818 LOC102642818 - +102642819 LOC102642819 - +102642832 LOC102642832 - +102642841 Gm38638 MGI:MGI:5621523 +102642842 Gm38639 MGI:MGI:5621524 +102642845 Gm38640 MGI:MGI:5621525 +102642864 LOC102642864 - +102642877 Gm38641 MGI:MGI:5621526 +102642880 Gm38642 MGI:MGI:5621527 +102642884 LOC102642884 - +102642900 Gm38643 MGI:MGI:5621528 +102642902 LOC102642902 - +102642924 Gm38644 MGI:MGI:5621529 +102642938 LOC102642938 - +102642939 LOC102642939 - +102642952 Gm38645 MGI:MGI:5621530 +102642954 LOC102642954 - +102642962 Gm38646 MGI:MGI:5621531 +102642976 Gm38647 MGI:MGI:5621532 +102642984 LOC102642984 - +102642986 Gm38648 MGI:MGI:5621533 +102642990 Gm38649 MGI:MGI:5621534 +102643016 Gm38650 MGI:MGI:5621535 +102643017 LOC102643017 - +102643033 LOC102643033 - +102643040 Gm38651 MGI:MGI:5621536 +102643046 Gm38652 MGI:MGI:5621537 +102643051 Gm38653 MGI:MGI:5621538 +102643069 Gm38654 MGI:MGI:5621539 +102643073 LOC102643073 - +102643076 Gm38655 MGI:MGI:5621540 +102643083 LOC102643083 - +102643088 Gm38656 MGI:MGI:5621541 +102643089 LOC102643089 - +102643091 Gm38657 MGI:MGI:5621542 +102643096 LOC102643096 - +102643121 Gm38658 MGI:MGI:5621543 +102643127 Gm38659 MGI:MGI:5621544 +102643128 Gm38660 MGI:MGI:5621545 +102643131 LOC102643131 - +102643136 LOC102643136 - +102643137 LOC102643137 - +102643147 Gm38661 MGI:MGI:5621546 +102643175 Gm38662 MGI:MGI:5621547 +102643180 LOC102643180 - +102643187 Gm38663 MGI:MGI:5621548 +102643210 Gm38664 MGI:MGI:5621549 +102643220 LOC102643220 - +102643244 Gm16252 MGI:MGI:3826521 +102643247 LOC102643247 - +102643257 LOC102643257 - +102643259 LOC102643259 - +102643269 LOC102643269 - +102643289 Gm38665 MGI:MGI:5621550 +102800312 Lncppara MGI:MGI:5568843 +102902673 Gm21992 MGI:MGI:5439461|Ensembl:ENSMUSG00000096370|Vega:OTTMUSG00000042311 +103164605 Paupar MGI:MGI:5543919|Ensembl:ENSMUSG00000102424 +103611158 Gm38666 MGI:MGI:5621551 +103611159 Gm38667 MGI:MGI:5621552 +103752557 B130002B16Rik MGI:MGI:5575994 +103752591 Gm38668 MGI:MGI:5621553 +103926449 Fkbp1a-ps4 MGI:MGI:5585257 +103926450 Rhox7-ps2 MGI:MGI:5615638 +104053954 Rhox11-ps3 MGI:MGI:3709647 +104053955 Rhox11-ps1 MGI:MGI:3705872 +104644204 KF876689 MGI:MGI:5603057 +104795665 Gm23363 MGI:MGI:5453140|Ensembl:ENSMUSG00000092765|miRBase:MI0030343 +104795666 Gm24572 MGI:MGI:5454349|Ensembl:ENSMUSG00000093246|miRBase:MI0030345 +104795667 Gm23450 MGI:MGI:5453227|Ensembl:ENSMUSG00000094210|miRBase:MI0030346 +104795949 Gm38670 MGI:MGI:5621555|Ensembl:ENSMUSG00000106236|miRBase:MI0031121 +104796139 Gm27740 MGI:MGI:5531122|Ensembl:ENSMUSG00000098621|miRBase:MI0031752 +104797221 Gm22650 MGI:MGI:5452427|Ensembl:ENSMUSG00000092879|miRBase:MI0030344 +104797311 Gm38671 MGI:MGI:5621556|Ensembl:ENSMUSG00000105030|miRBase:MI0031120 +104797374 Gm25285 MGI:MGI:5455062|Ensembl:ENSMUSG00000095536|miRBase:MI0031753 +104940697 Dalir MGI:MGI:5579231|Ensembl:ENSMUSG00000099784 +105180375 Tmem265 MGI:MGI:5613213|Ensembl:ENSMUSG00000106715|Vega:OTTMUSG00000055776 +105180380 D030009A17Rik MGI:MGI:5608887 +105180381 D430042D18Rik MGI:MGI:5608889 +105180382 BC024929 MGI:MGI:5608893 +105180383 A230095H09Rik MGI:MGI:5608993 +105180384 F830230K02Rik MGI:MGI:5608997 +105180385 F830047L01Rik MGI:MGI:5608995 +105180386 E130116C07Rik MGI:MGI:5608915 +105180387 B230210A14Rik MGI:MGI:5608885 +105180388 A130047H01Rik MGI:MGI:5608891 +105180389 B930083L10Rik MGI:MGI:5608918 +105242387 LOC105242387 - +105242388 Gm38672 MGI:MGI:5621557 +105242389 Gm38673 MGI:MGI:5621558 +105242390 Gm38674 MGI:MGI:5621559 +105242391 Gm38675 MGI:MGI:5621560 +105242392 Gm38676 MGI:MGI:5621561 +105242393 Gm38677 MGI:MGI:5621562 +105242394 Gm38678 MGI:MGI:5621563 +105242395 Gm38679 MGI:MGI:5621564 +105242396 Gm38680 MGI:MGI:5621565 +105242397 Gm38681 MGI:MGI:5621566 +105242399 LOC105242399 Ensembl:ENSMUSG00000096878|Vega:OTTMUSG00000055282 +105242400 Gm38682 MGI:MGI:5621567 +105242401 LOC105242401 - +105242403 LOC105242403 - +105242404 LOC105242404 - +105242405 LOC105242405 - +105242407 Gm38684 MGI:MGI:5621569 +105242408 Gm45918 MGI:MGI:5825555 +105242409 Gm43131 MGI:MGI:5663268 +105242410 LOC105242410 - +105242411 Gm38685 MGI:MGI:5621570 +105242412 Gm38686 MGI:MGI:5621571 +105242414 Gm38687 MGI:MGI:5621572 +105242415 Gm38688 MGI:MGI:5621573 +105242417 LOC105242417 - +105242418 Gm38690 MGI:MGI:5621575 +105242419 Gm38691 MGI:MGI:5621576 +105242420 Gm38692 MGI:MGI:5621577 +105242421 Gm45919 MGI:MGI:5825556 +105242422 Gm38693 MGI:MGI:5621578 +105242425 Gm38695 MGI:MGI:5621580 +105242426 Gm38696 MGI:MGI:5621581 +105242427 Gm38697 MGI:MGI:5621582 +105242428 Gm38698 MGI:MGI:5621583 +105242429 LOC105242429 - +105242430 Gm38699 MGI:MGI:5621584 +105242431 Gm38700 MGI:MGI:5621585 +105242432 Gm38701 MGI:MGI:5621586 +105242433 Gm38702 MGI:MGI:5621587 +105242434 Gm38703 MGI:MGI:5621588 +105242435 Gm38704 MGI:MGI:5621589 +105242436 Gm38705 MGI:MGI:5621590 +105242437 LOC105242437 - +105242438 LOC105242438 - +105242439 Gm38706 MGI:MGI:5621591 +105242440 Gm38707 MGI:MGI:5621592 +105242442 LOC105242442 - +105242443 Gm38708 MGI:MGI:5621593 +105242444 Gm38709 MGI:MGI:5621594 +105242445 Gm38710 MGI:MGI:5621595 +105242446 Gm20474 MGI:MGI:5141939 +105242447 Gm38712 MGI:MGI:5621597 +105242448 Gm38713 MGI:MGI:5621598 +105242449 LOC105242449 Ensembl:ENSMUSG00000094811|Vega:OTTMUSG00000036266 +105242450 Gm38714 MGI:MGI:5621599 +105242451 Gm38715 MGI:MGI:5621600 +105242452 LOC105242452 - +105242453 LOC105242453 - +105242455 Gm38716 MGI:MGI:5621601 +105242462 LOC105242462 - +105242466 LOC105242466 - +105242467 Gm38717 MGI:MGI:5621602 +105242468 LOC105242468 - +105242472 LOC105242472 - +105242475 LOC105242475 - +105242480 LOC105242480 - +105242481 LOC105242481 - +105242482 LOC105242482 - +105242483 LOC105242483 - +105242485 LOC105242485 - +105242488 LOC105242488 - +105242493 LOC105242493 - +105242496 LOC105242496 - +105242502 LOC105242502 - +105242506 Gm38718 MGI:MGI:5621603 +105242517 Gm38719 MGI:MGI:5621604 +105242528 Gm38720 MGI:MGI:5621605 +105242531 Gm38721 MGI:MGI:5621606 +105242533 LOC105242533 - +105242534 Gm38722 MGI:MGI:5621607 +105242535 Gm20485 MGI:MGI:5141950 +105242537 Gm38723 MGI:MGI:5621608 +105242538 Gm38724 MGI:MGI:5621609 +105242540 Gm38725 MGI:MGI:5621610 +105242541 LOC105242541 - +105242542 Gm38726 MGI:MGI:5621611 +105242543 Gm15672 MGI:MGI:3783114 +105242544 Gm38727 MGI:MGI:5621612 +105242545 Gm16120 MGI:MGI:3802132 +105242546 Gm38728 MGI:MGI:5621613 +105242547 Gm38729 MGI:MGI:5621614 +105242548 Gm38730 MGI:MGI:5621615 +105242549 Gm16036 MGI:MGI:3801891 +105242550 Gm38731 MGI:MGI:5621616 +105242552 Gm38732 MGI:MGI:5621617 +105242554 Gm38733 MGI:MGI:5621618 +105242555 Gm38734 MGI:MGI:5621619 +105242556 Gm38735 MGI:MGI:5621620 +105242557 Gm20635 MGI:MGI:5313082 +105242558 Gm38736 MGI:MGI:5621621 +105242559 Gm38737 MGI:MGI:5621622 +105242560 Gm38738 MGI:MGI:5621623 +105242562 Gm38739 MGI:MGI:5621624 +105242563 Gm38740 MGI:MGI:5621625 +105242564 Gm38741 MGI:MGI:5621626 +105242566 Gm38742 MGI:MGI:5621627 +105242567 Gm38743 MGI:MGI:5621628 +105242569 LOC105242569 - +105242570 Gm38744 MGI:MGI:5621629 +105242571 Gm38745 MGI:MGI:5621630 +105242572 Gm38746 MGI:MGI:5621631 +105242573 Gm38747 MGI:MGI:5621632 +105242574 Gm38748 MGI:MGI:5621633 +105242575 Gm38749 MGI:MGI:5621634 +105242576 Gm38750 MGI:MGI:5621635 +105242577 Gm38751 MGI:MGI:5621636 +105242578 Gm38752 MGI:MGI:5621637 +105242579 Gm42788 MGI:MGI:5662925|Ensembl:ENSMUSG00000107388 +105242580 Gm38753 MGI:MGI:5621638 +105242581 LOC105242581 - +105242582 Gm38754 MGI:MGI:5621639 +105242583 Gm38755 MGI:MGI:5621640 +105242585 Gm38756 MGI:MGI:5621641 +105242586 Gm38757 MGI:MGI:5621642 +105242587 Gm38758 MGI:MGI:5621643 +105242589 Gm38759 MGI:MGI:5621644 +105242590 Gm38760 MGI:MGI:5621645 +105242591 Gm38761 MGI:MGI:5621646 +105242592 Gm38762 MGI:MGI:5621647 +105242593 Gm20618 MGI:MGI:5313065 +105242594 Gm38763 MGI:MGI:5621648 +105242595 LOC105242595 - +105242596 Gm38764 MGI:MGI:5621649 +105242597 Gm38765 MGI:MGI:5621650 +105242598 Gm38766 MGI:MGI:5621651 +105242599 Gm38767 MGI:MGI:5621652 +105242600 Gm38768 MGI:MGI:5621653 +105242601 Gm38769 MGI:MGI:5621654 +105242602 Gm38770 MGI:MGI:5621655 +105242603 Gm38771 MGI:MGI:5621656 +105242604 Gm38772 MGI:MGI:5621657 +105242605 Gm38773 MGI:MGI:5621658 +105242606 Gm38774 MGI:MGI:5621659 +105242607 Gm38775 MGI:MGI:5621660 +105242608 Gm38776 MGI:MGI:5621661 +105242609 Gm38777 MGI:MGI:5621662 +105242610 Gm38778 MGI:MGI:5621663 +105242611 Gm38779 MGI:MGI:5621664 +105242612 Gm26627 MGI:MGI:5477121 +105242613 Gm38780 MGI:MGI:5621665 +105242615 Gm13781 MGI:MGI:3649768 +105242616 Gm38781 MGI:MGI:5621666 +105242618 Gm38782 MGI:MGI:5621667 +105242619 Gm38783 MGI:MGI:5621668 +105242620 Gm38784 MGI:MGI:5621669 +105242621 LOC105242621 - +105242622 Gm13846 MGI:MGI:3651995 +105242623 Gm13850 MGI:MGI:3651993 +105242624 Gm38785 MGI:MGI:5621670 +105242625 Gm38786 MGI:MGI:5621671 +105242626 Gm13855 MGI:MGI:3652198 +105242627 Gm14546 MGI:MGI:3705210 +105242628 Gm38787 MGI:MGI:5621672 +105242629 Gm38788 MGI:MGI:5621673 +105242630 Gm38789 MGI:MGI:5621674 +105242631 Gm38790 MGI:MGI:5621675 +105242632 Gm38791 MGI:MGI:5621676 +105242633 Gm38792 MGI:MGI:5621677 +105242634 Gm38793 MGI:MGI:5621678 +105242635 Gm38794 MGI:MGI:5621679 +105242636 Gm38795 MGI:MGI:5621680 +105242637 Gm38796 MGI:MGI:5621681 +105242638 Gm38797 MGI:MGI:5621682 +105242639 Gm38798 MGI:MGI:5621683 +105242640 Gm38799 MGI:MGI:5621684 +105242642 Gm38800 MGI:MGI:5621685 +105242643 Gm38801 MGI:MGI:5621686 +105242644 LOC105242644 - +105242646 Gm38802 MGI:MGI:5621687 +105242647 Gm38803 MGI:MGI:5621688 +105242648 Gm38804 MGI:MGI:5621689 +105242649 Gm38805 MGI:MGI:5621690 +105242651 Gm38806 MGI:MGI:5621691 +105242652 Gm38807 MGI:MGI:5621692 +105242653 Gm38808 MGI:MGI:5621693 +105242654 Gm38809 MGI:MGI:5621694 +105242655 Gm38810 MGI:MGI:5621695 +105242656 Gm38811 MGI:MGI:5621696 +105242657 Hoxaas2 MGI:MGI:1913890|Ensembl:ENSMUSG00000056445 +105242658 Hotairm1 MGI:MGI:3705155|Ensembl:ENSMUSG00000087658 +105242659 Gm38812 MGI:MGI:5621697 +105242660 Gm38813 MGI:MGI:5621698 +105242661 Gm38814 MGI:MGI:5621699 +105242662 Gm38815 MGI:MGI:5621700 +105242663 Gm38816 MGI:MGI:5621701 +105242664 Gm38817 MGI:MGI:5621702 +105242665 Gm38818 MGI:MGI:5621703 +105242666 Gm38819 MGI:MGI:5621704 +105242667 Gm38820 MGI:MGI:5621705 +105242668 Gm38821 MGI:MGI:5621706 +105242670 Gm38822 MGI:MGI:5621707 +105242671 Gm38823 MGI:MGI:5621708 +105242673 Gm38824 MGI:MGI:5621709 +105242674 Gm38825 MGI:MGI:5621710 +105242675 Gm38826 MGI:MGI:5621711 +105242676 Gm38827 MGI:MGI:5621712 +105242677 Gm38828 MGI:MGI:5621713 +105242678 Gm38829 MGI:MGI:5621714 +105242679 Gm38830 MGI:MGI:5621715 +105242680 LOC105242680 - +105242681 Gm38831 MGI:MGI:5621716 +105242682 Gm38832 MGI:MGI:5621717 +105242683 Gm38833 MGI:MGI:5621718 +105242685 Gm38834 MGI:MGI:5621719 +105242686 Gm38835 MGI:MGI:5621720 +105242687 Gm38836 MGI:MGI:5621721 +105242688 Gm38837 MGI:MGI:5621722 +105242690 Gm38838 MGI:MGI:5621723 +105242691 Gm38839 MGI:MGI:5621724 +105242692 Gm38840 MGI:MGI:5621725 +105242693 Gm38841 MGI:MGI:5621726 +105242694 Gm38842 MGI:MGI:5621727 +105242696 Gm38843 MGI:MGI:5621728 +105242698 Gm38844 MGI:MGI:5621729 +105242699 Gm38845 MGI:MGI:5621730 +105242700 Gm38846 MGI:MGI:5621731 +105242701 LOC105242701 - +105242703 Gm38847 MGI:MGI:5621732 +105242704 Gm38848 MGI:MGI:5621733 +105242705 Gm38849 MGI:MGI:5621734 +105242706 Gm38850 MGI:MGI:5621735 +105242708 Gm38851 MGI:MGI:5621736 +105242709 Gm38852 MGI:MGI:5621737 +105242710 Gm38853 MGI:MGI:5621738 +105242711 Gm38854 MGI:MGI:5621739 +105242712 Gm38855 MGI:MGI:5621740 +105242713 Gm38856 MGI:MGI:5621741 +105242714 Gm38857 MGI:MGI:5621742 +105242715 Gm38858 MGI:MGI:5621743 +105242716 Gm38859 MGI:MGI:5621744 +105242717 Gm38860 MGI:MGI:5621745 +105242719 Gm38861 MGI:MGI:5621746 +105242720 Gm38862 MGI:MGI:5621747 +105242721 Gm38863 MGI:MGI:5621748 +105242722 Gm38864 MGI:MGI:5621749 +105242725 Gm38865 MGI:MGI:5621750 +105242726 Gm38866 MGI:MGI:5621751 +105242727 Gm38867 MGI:MGI:5621752 +105242728 Gm38868 MGI:MGI:5621753 +105242729 Gm38869 MGI:MGI:5621754 +105242731 Gm38870 MGI:MGI:5621755 +105242732 Gm38871 MGI:MGI:5621756 +105242735 Gm38872 MGI:MGI:5621757 +105242736 LOC105242736 - +105242737 Gm38873 MGI:MGI:5621758 +105242738 Gm26799 MGI:MGI:5477293 +105242740 Gm38874 MGI:MGI:5621759 +105242741 Gm38875 MGI:MGI:5621760 +105242742 Gm38876 MGI:MGI:5621761 +105242743 Gm38877 MGI:MGI:5621762 +105242744 Gm38878 MGI:MGI:5621763 +105242745 Gm38879 MGI:MGI:5621764 +105242748 Gm38880 MGI:MGI:5621765 +105242749 Gm38881 MGI:MGI:5621766 +105242750 Gm38882 MGI:MGI:5621767 +105242751 Gm38883 MGI:MGI:5621768 +105242752 Gm38884 MGI:MGI:5621769 +105242753 Gm38885 MGI:MGI:5621770 +105242754 Gm38886 MGI:MGI:5621771 +105242756 Gm38887 MGI:MGI:5621772 +105242758 Gm38888 MGI:MGI:5621773 +105242759 Gm38889 MGI:MGI:5621774 +105242760 Gm38890 MGI:MGI:5621775 +105242761 Gm38891 MGI:MGI:5621776 +105242762 Gm38892 MGI:MGI:5621777 +105242763 Gm38893 MGI:MGI:5621778 +105242765 Gm38894 MGI:MGI:5621779 +105242766 Gm38895 MGI:MGI:5621780 +105242768 Gm38896 MGI:MGI:5621781 +105242769 Gm24175 MGI:MGI:5453952 +105242770 Gm38897 MGI:MGI:5621782 +105242771 Gm38898 MGI:MGI:5621783 +105242773 Gm38899 MGI:MGI:5621784 +105242774 Gm38900 MGI:MGI:5621785 +105242776 Gm38901 MGI:MGI:5621786 +105242778 Gm38902 MGI:MGI:5621787 +105242780 Gm38903 MGI:MGI:5621788 +105242781 Gm38904 MGI:MGI:5621789 +105242784 Gm38905 MGI:MGI:5621790 +105242785 Gm38906 MGI:MGI:5621791 +105242790 LOC105242790 - +105242792 Adap2os MGI:MGI:3650197 +105242793 Gm38907 MGI:MGI:5621792 +105242794 Gm38908 MGI:MGI:5621793 +105242795 Gm38909 MGI:MGI:5621794 +105242797 Gm38910 MGI:MGI:5621795 +105242798 LOC105242798 - +105242799 Gm38911 MGI:MGI:5621796 +105242800 Gm14329 MGI:MGI:3651759|Ensembl:ENSMUSG00000086239 +105242801 Gm38912 MGI:MGI:5621797 +105242802 LOC105242802 - +105242803 Gm38913 MGI:MGI:5621798 +105242804 Gm38914 MGI:MGI:5621799 +105242805 Gm38915 MGI:MGI:5621800 +105242806 Gm38916 MGI:MGI:5621801 +105242808 Gm38917 MGI:MGI:5621802 +105242809 Gm38918 MGI:MGI:5621803 +105242810 Gm38919 MGI:MGI:5621804 +105242811 Gm38920 MGI:MGI:5621805 +105242812 Gm38921 MGI:MGI:5621806 +105242813 Gm38922 MGI:MGI:5621807 +105242814 Gm38923 MGI:MGI:5621808 +105242815 Gm38924 MGI:MGI:5621809 +105242816 Gm38925 MGI:MGI:5621810 +105242817 Gm15543 MGI:MGI:3782992|Ensembl:ENSMUSG00000086863 +105242818 Gm38926 MGI:MGI:5621811 +105242821 Gm38927 MGI:MGI:5621812 +105242822 Sspnos MGI:MGI:3783145 +105242823 Gm38928 MGI:MGI:5621813 +105242825 Gm38929 MGI:MGI:5621814 +105242826 LOC105242826 - +105242828 Gm38930 MGI:MGI:5621815 +105242829 Gm38931 MGI:MGI:5621816 +105242830 Gm38932 MGI:MGI:5621817 +105242831 Gm38933 MGI:MGI:5621818 +105242833 Gm38934 MGI:MGI:5621819 +105242836 Gm38935 MGI:MGI:5621820 +105242837 Gm38936 MGI:MGI:5621821 +105242838 Gm38937 MGI:MGI:5621822 +105242840 Gm45920 MGI:MGI:5825557 +105242841 Gm38938 MGI:MGI:5621823 +105242842 Gm38939 MGI:MGI:5621824 +105242843 Gm38940 MGI:MGI:5621825 +105242844 Gm38941 MGI:MGI:5621826 +105242845 Gm38942 MGI:MGI:5621827 +105242846 Gm38943 MGI:MGI:5621828 +105242847 Gm38944 MGI:MGI:5621829 +105242848 Gm38945 MGI:MGI:5621830 +105242850 Gm38946 MGI:MGI:5621831 +105242851 Gm38947 MGI:MGI:5621832 +105242854 Gm38948 MGI:MGI:5621833 +105242855 Gm38949 MGI:MGI:5621834 +105242856 Gm38950 MGI:MGI:5621835 +105242858 Gm38951 MGI:MGI:5621836 +105242860 Gm38952 MGI:MGI:5621837 +105242861 Gm38953 MGI:MGI:5621838 +105242862 Gm26802 MGI:MGI:5477296 +105242863 Gm38954 MGI:MGI:5621839 +105242864 Gm38955 MGI:MGI:5621840 +105242865 Gm38956 MGI:MGI:5621841 +105242868 Gm38957 MGI:MGI:5621842 +105242869 Gm38958 MGI:MGI:5621843 +105242870 Gm38959 MGI:MGI:5621844 +105242871 Gm38960 MGI:MGI:5621845 +105242873 Gm38961 MGI:MGI:5621846 +105242874 Gm38962 MGI:MGI:5621847 +105242875 Gm38963 MGI:MGI:5621848 +105242876 Gm38964 MGI:MGI:5621849 +105242877 Gm38965 MGI:MGI:5621850 +105242878 Gm38966 MGI:MGI:5621851 +105242879 Gm38967 MGI:MGI:5621852 +105242880 Gm38968 MGI:MGI:5621853 +105242881 Gm38969 MGI:MGI:5621854 +105242884 Gm38970 MGI:MGI:5621855 +105242885 Gm38971 MGI:MGI:5621856 +105242886 Gm38972 MGI:MGI:5621857 +105242887 Gm15541 MGI:MGI:3782989 +105242888 Gm38973 MGI:MGI:5621858 +105242889 Gm38974 MGI:MGI:5621859 +105242890 Gm38975 MGI:MGI:5621860 +105242891 LOC105242891 - +105242892 Gm38976 MGI:MGI:5621861 +105242893 Gm38977 MGI:MGI:5621862 +105242894 Gm38978 MGI:MGI:5621863 +105242895 Gm38979 MGI:MGI:5621864 +105242896 Gm38980 MGI:MGI:5621865 +105242897 Gm38981 MGI:MGI:5621866 +105242898 Gm38982 MGI:MGI:5621867 +105242900 Gm38983 MGI:MGI:5621868 +105242901 Gm38984 MGI:MGI:5621869 +105242904 Gm38985 MGI:MGI:5621870 +105242905 Gm38986 MGI:MGI:5621871 +105242906 Gm12763 MGI:MGI:3649978 +105242907 LOC105242907 - +105242908 Gm38987 MGI:MGI:5621872 +105242909 Gm38988 MGI:MGI:5621873 +105242910 Gm38989 MGI:MGI:5621874 +105242911 Gm38990 MGI:MGI:5621875 +105242912 Gm38991 MGI:MGI:5621876 +105242913 Gm38992 MGI:MGI:5621877 +105242914 Gm38993 MGI:MGI:5621878 +105242916 LOC105242916 - +105242917 Gm38994 MGI:MGI:5621879 +105242918 Gm38995 MGI:MGI:5621880 +105242920 LOC105242920 - +105242922 Gm38996 MGI:MGI:5621881 +105242923 Gm38997 MGI:MGI:5621882 +105242926 Gm38998 MGI:MGI:5621883 +105242927 Gm38999 MGI:MGI:5621884|Ensembl:ENSMUSG00000093639|Ensembl:ENSMUSG00000097437|Vega:OTTMUSG00000039804|Vega:OTTMUSG00000042533 +105242928 Gm39000 MGI:MGI:5621885 +105242929 Gm39001 MGI:MGI:5621886 +105242930 Gm39002 MGI:MGI:5621887 +105242931 Gm39003 MGI:MGI:5621888 +105242932 Gm39004 MGI:MGI:5621889 +105242933 Gm39005 MGI:MGI:5621890 +105242934 Gm39006 MGI:MGI:5621891 +105242935 Gm39007 MGI:MGI:5621892 +105242936 Gm39008 MGI:MGI:5621893 +105242937 Gm39009 MGI:MGI:5621894 +105242938 Gm39010 MGI:MGI:5621895 +105242939 Gm39011 MGI:MGI:5621896 +105242940 Gm39012 MGI:MGI:5621897 +105242941 Gm39013 MGI:MGI:5621898 +105242943 Gm39014 MGI:MGI:5621899 +105242944 Gm39015 MGI:MGI:5621900 +105242945 Gm39016 MGI:MGI:5621901 +105242946 Gm39017 MGI:MGI:5621902 +105242947 Gm39018 MGI:MGI:5621903 +105242948 Gm39019 MGI:MGI:5621904 +105242949 Gm39020 MGI:MGI:5621905 +105242952 LOC105242952 - +105242956 Gm39021 MGI:MGI:5621906 +105242958 Gm39022 MGI:MGI:5621907 +105242959 Gm39023 MGI:MGI:5621908 +105242960 Gm39024 MGI:MGI:5621909 +105242962 Gm39025 MGI:MGI:5621910 +105242963 Gm39026 MGI:MGI:5621911 +105242964 Gm39027 MGI:MGI:5621912 +105242965 Gm39028 MGI:MGI:5621913 +105242966 Gm16158 MGI:MGI:3801750 +105242967 Gm39029 MGI:MGI:5621914 +105242968 Gm39030 MGI:MGI:5621915 +105242969 Gm39031 MGI:MGI:5621916 +105242970 Gm39032 MGI:MGI:5621917 +105242971 Gm39033 MGI:MGI:5621918 +105242972 Gm39034 MGI:MGI:5621919 +105242973 Gm39035 MGI:MGI:5621920 +105242975 Gm39036 MGI:MGI:5621921 +105242976 Gm39037 MGI:MGI:5621922 +105242978 Gm39038 MGI:MGI:5621923 +105242979 Gm39039 MGI:MGI:5621924 +105242980 Gm39040 MGI:MGI:5621925 +105242981 Gm39041 MGI:MGI:5621926 +105242982 Gm39042 MGI:MGI:5621927 +105242985 Gm39043 MGI:MGI:5621928 +105242986 Gm39044 MGI:MGI:5621929 +105242987 Gm39045 MGI:MGI:5621930 +105242990 Gm39046 MGI:MGI:5621931 +105242991 Gm39047 MGI:MGI:5621932 +105242994 Gm39048 MGI:MGI:5621933 +105242997 Gm39049 MGI:MGI:5621934 +105243000 Gm39050 MGI:MGI:5621935 +105243001 Gm39051 MGI:MGI:5621936 +105243002 Gm39052 MGI:MGI:5621937 +105243003 Gm39053 MGI:MGI:5621938 +105243004 LOC105243004 - +105243005 Gm39054 MGI:MGI:5621939 +105243006 Gm39055 MGI:MGI:5621940 +105243007 Gm39056 MGI:MGI:5621941 +105243008 Gm39057 MGI:MGI:5621942 +105243010 Gm39058 MGI:MGI:5621943 +105243011 Gm39059 MGI:MGI:5621944 +105243012 Gm39060 MGI:MGI:5621945 +105243016 Gm39061 MGI:MGI:5621946 +105243018 Gm39062 MGI:MGI:5621947 +105243022 Gm39063 MGI:MGI:5621948 +105243023 Gm39064 MGI:MGI:5621949 +105243024 Gm39065 MGI:MGI:5621950 +105243025 Gm39066 MGI:MGI:5621951 +105243026 Gm39067 MGI:MGI:5621952 +105243027 Gm39068 MGI:MGI:5621953 +105243028 Gm39069 MGI:MGI:5621954 +105243029 Gm39070 MGI:MGI:5621955 +105243030 Gm39071 MGI:MGI:5621956 +105243031 Gm39072 MGI:MGI:5621957 +105243036 Gm39073 MGI:MGI:5621958 +105243037 Gm39074 MGI:MGI:5621959 +105243038 Gm39075 MGI:MGI:5621960 +105243040 Gm39076 MGI:MGI:5621961 +105243041 Gm39077 MGI:MGI:5621962 +105243042 Gm39078 MGI:MGI:5621963 +105243043 Gm39079 MGI:MGI:5621964 +105243044 Gm39080 MGI:MGI:5621965 +105243045 Gm15774 MGI:MGI:3783215 +105243046 Gm39081 MGI:MGI:5621966 +105243048 Gm39082 MGI:MGI:5621967 +105243049 Gm39083 MGI:MGI:5621968 +105243050 Gm39084 MGI:MGI:5621969 +105243052 Gm39085 MGI:MGI:5621970 +105243053 LOC105243053 - +105243054 Gm39086 MGI:MGI:5621971 +105243055 Gm39087 MGI:MGI:5621972 +105243056 Gm39088 MGI:MGI:5621973 +105243057 Gm39089 MGI:MGI:5621974 +105243058 Gm39090 MGI:MGI:5621975 +105243059 Gm39091 MGI:MGI:5621976 +105243060 Gm39092 MGI:MGI:5621977 +105243062 Gm39093 MGI:MGI:5621978 +105243063 Gm39094 MGI:MGI:5621979 +105243064 Gm39095 MGI:MGI:5621980 +105243065 Gm39096 MGI:MGI:5621981 +105243066 Gm39097 MGI:MGI:5621982 +105243067 Gm39098 MGI:MGI:5621983 +105243068 Gm39099 MGI:MGI:5621984 +105243070 Gm39100 MGI:MGI:5621985 +105243071 Gm39101 MGI:MGI:5621986 +105243072 Gm39102 MGI:MGI:5621987 +105243073 LOC105243073 - +105243074 Gm39103 MGI:MGI:5621988 +105243075 Gm39104 MGI:MGI:5621989 +105243076 Gm39105 MGI:MGI:5621990 +105243077 Gm39106 MGI:MGI:5621991 +105243078 Gm39107 MGI:MGI:5621992 +105243080 Gm39108 MGI:MGI:5621993 +105243081 Gm39109 MGI:MGI:5621994 +105243082 Gm39110 MGI:MGI:5621995 +105243084 Gm39111 MGI:MGI:5621996 +105243086 Gm39112 MGI:MGI:5621997 +105243087 Gm39113 MGI:MGI:5621998 +105243088 Gm39114 MGI:MGI:5621999 +105243089 Gm39115 MGI:MGI:5622000|Ensembl:ENSMUSG00000110091|Vega:OTTMUSG00000060160 +105243090 LOC105243090 Ensembl:ENSMUSG00000073786|Vega:OTTMUSG00000048009 +105243092 Gm39116 MGI:MGI:5622001 +105243094 Gm39117 MGI:MGI:5622002 +105243095 Gm15579 MGI:MGI:3783027 +105243096 Gm39118 MGI:MGI:5622003 +105243098 Gm39119 MGI:MGI:5622004 +105243100 Gm39120 MGI:MGI:5622005 +105243101 LOC105243101 - +105243109 Gm39121 MGI:MGI:5622006 +105243110 Gm39122 MGI:MGI:5622007 +105243111 LOC105243111 - +105243112 Gm39123 MGI:MGI:5622008 +105243113 Gm39124 MGI:MGI:5622009 +105243114 Gm39125 MGI:MGI:5622010 +105243115 Gm39126 MGI:MGI:5622011 +105243116 Gm39127 MGI:MGI:5622012 +105243117 Gm39128 MGI:MGI:5622013|Ensembl:ENSMUSG00000109064 +105243118 Gm39129 MGI:MGI:5622014 +105243119 Gm39130 MGI:MGI:5622015 +105243120 Gm39131 MGI:MGI:5622016 +105243121 Gm39132 MGI:MGI:5622017 +105243123 Gm39133 MGI:MGI:5622018 +105243124 Gm15351 MGI:MGI:3705299 +105243125 LOC105243125 - +105243127 LOC105243127 - +105243128 Gm39134 MGI:MGI:5622019 +105243130 Gm39135 MGI:MGI:5622020 +105243132 Gm39136 MGI:MGI:5622021 +105243134 Gm39137 MGI:MGI:5622022 +105243135 Gm39138 MGI:MGI:5622023 +105243136 Gm39139 MGI:MGI:5622024 +105243137 Gm39140 MGI:MGI:5622025 +105243138 Gm15346 MGI:MGI:3705174 +105243139 LOC105243139 - +105243140 Gm39141 MGI:MGI:5622026 +105243141 Gm39142 MGI:MGI:5622027 +105243143 Gm39143 MGI:MGI:5622028 +105243144 Gm39144 MGI:MGI:5622029 +105243145 Gm39145 MGI:MGI:5622030 +105243146 Gm39146 MGI:MGI:5622031 +105243147 Gm39147 MGI:MGI:5622032 +105243149 Gm39148 MGI:MGI:5622033 +105243150 Gm39149 MGI:MGI:5622034 +105243151 Gm39150 MGI:MGI:5622035 +105243152 Gm39151 MGI:MGI:5622036 +105243153 Gm39152 MGI:MGI:5622037 +105243154 Gm39153 MGI:MGI:5622038 +105243155 Gm26795 MGI:MGI:5477289 +105243156 Gm39154 MGI:MGI:5622039 +105243158 Gm39155 MGI:MGI:5622040 +105243159 LOC105243159 - +105243160 Gm39156 MGI:MGI:5622041 +105243162 Gm39157 MGI:MGI:5622042 +105243163 Gm39158 MGI:MGI:5622043|Ensembl:ENSMUSG00000109869 +105243165 Gm39159 MGI:MGI:5622044 +105243166 Gm39160 MGI:MGI:5622045 +105243167 Gm9939 MGI:MGI:3708775 +105243169 Gm39161 MGI:MGI:5622046 +105243170 Gm39162 MGI:MGI:5622047 +105243171 Gm39163 MGI:MGI:5622048 +105243172 Gm39164 MGI:MGI:5622049 +105243173 Gm39165 MGI:MGI:5622050 +105243174 Gm39166 MGI:MGI:5622051 +105243175 Gm39167 MGI:MGI:5622052 +105243176 LOC105243176 - +105243177 Gm39168 MGI:MGI:5622053|Ensembl:ENSMUSG00000110179 +105243178 Gm39169 MGI:MGI:5622054 +105243179 Gm39170 MGI:MGI:5622055 +105243181 Gm39171 MGI:MGI:5622056 +105243182 Gm39172 MGI:MGI:5622057 +105243183 Gm39173 MGI:MGI:5622058 +105243184 LOC105243184 Ensembl:ENSMUSG00000110464 +105243185 Gm39174 MGI:MGI:5622059 +105243186 Gm39175 MGI:MGI:5622060 +105243187 Gm39176 MGI:MGI:5622061 +105243188 Gm39177 MGI:MGI:5622062 +105243189 Gm39178 MGI:MGI:5622063 +105243190 Gm39179 MGI:MGI:5622064 +105243191 Gm39180 MGI:MGI:5622065 +105243192 Gm39181 MGI:MGI:5622066 +105243193 Gm39182 MGI:MGI:5622067 +105243194 LOC105243194 - +105243196 Gm39183 MGI:MGI:5622068 +105243197 Gm39184 MGI:MGI:5622069 +105243198 Gm39185 MGI:MGI:5622070 +105243200 Gm39186 MGI:MGI:5622071 +105243202 Gm39187 MGI:MGI:5622072 +105243203 Gm39188 MGI:MGI:5622073 +105243205 Gm39189 MGI:MGI:5622074 +105243207 LOC105243207 - +105243208 Gm39190 MGI:MGI:5622075 +105243209 Gm39191 MGI:MGI:5622076 +105243210 Gm17576 MGI:MGI:4937210 +105243211 Gm39192 MGI:MGI:5622077 +105243212 Gm39193 MGI:MGI:5622078 +105243213 Gm39194 MGI:MGI:5622079 +105243215 Gm39195 MGI:MGI:5622080 +105243217 Gm39196 MGI:MGI:5622081 +105243218 Gm39197 MGI:MGI:5622082 +105243219 Gm39198 MGI:MGI:5622083 +105243220 Gm39199 MGI:MGI:5622084 +105243221 Gm39200 MGI:MGI:5622085 +105243222 Gm39201 MGI:MGI:5622086 +105243223 LOC105243223 - +105243224 Gm39202 MGI:MGI:5622087 +105243225 Gm39203 MGI:MGI:5622088 +105243226 Gm39204 MGI:MGI:5622089 +105243227 Gm39205 MGI:MGI:5622090 +105243228 Gm39206 MGI:MGI:5622091 +105243229 Gm39207 MGI:MGI:5622092 +105243230 Gm39208 MGI:MGI:5622093 +105243231 Gm39209 MGI:MGI:5622094 +105243233 LOC105243233 - +105243235 Gm26721 MGI:MGI:5477215 +105243236 Gm39210 MGI:MGI:5622095 +105243237 Gm39211 MGI:MGI:5622096 +105243238 Gm39212 MGI:MGI:5622097 +105243239 Gm39213 MGI:MGI:5622098 +105243241 Gm39214 MGI:MGI:5622099 +105243242 Gm39215 MGI:MGI:5622100 +105243243 Gm39216 MGI:MGI:5622101 +105243244 Gm39217 MGI:MGI:5622102 +105243245 Gm39218 MGI:MGI:5622103 +105243246 Gm39219 MGI:MGI:5622104 +105243247 Gm39220 MGI:MGI:5622105 +105243249 Gm39221 MGI:MGI:5622106 +105243251 Gm39222 MGI:MGI:5622107 +105243252 Gm39223 MGI:MGI:5622108 +105243253 Gm28516 MGI:MGI:5579222|Ensembl:ENSMUSG00000101613 +105243254 Gm39224 MGI:MGI:5622109 +105243255 Gm39225 MGI:MGI:5622110 +105243257 Gm39226 MGI:MGI:5622111 +105243258 Gm39227 MGI:MGI:5622112 +105243259 Gm39228 MGI:MGI:5622113 +105243260 Gm39229 MGI:MGI:5622114 +105243261 Gm39230 MGI:MGI:5622115 +105243262 Gm39231 MGI:MGI:5622116 +105243264 Gm39232 MGI:MGI:5622117 +105243265 Gm39233 MGI:MGI:5622118 +105243266 Gm39234 MGI:MGI:5622119 +105243267 Gm39235 MGI:MGI:5622120 +105243268 Gm39236 MGI:MGI:5622121 +105243269 LOC105243269 - +105243271 Gm39237 MGI:MGI:5622122 +105243273 Gm39238 MGI:MGI:5622123 +105243274 Gm39239 MGI:MGI:5622124 +105243276 Gm39240 MGI:MGI:5622125 +105243277 Gm39241 MGI:MGI:5622126 +105243278 Gm39242 MGI:MGI:5622127 +105243279 Gm39243 MGI:MGI:5622128 +105243280 Gm39244 MGI:MGI:5622129 +105243281 Gm39245 MGI:MGI:5622130 +105243282 LOC105243282 - +105243283 Gm39246 MGI:MGI:5622131 +105243284 Gm39247 MGI:MGI:5622132 +105243285 Gm39248 MGI:MGI:5622133 +105243286 Gm39249 MGI:MGI:5622134 +105243287 Gm39250 MGI:MGI:5622135 +105243288 Gm39251 MGI:MGI:5622136 +105243289 LOC105243289 - +105243290 Gm39252 MGI:MGI:5622137 +105243291 Gm39253 MGI:MGI:5622138 +105243292 Gm39254 MGI:MGI:5622139 +105243293 Gm39255 MGI:MGI:5622140 +105243294 Gm39256 MGI:MGI:5622141 +105243295 Gm39257 MGI:MGI:5622142 +105243297 Gm39258 MGI:MGI:5622143 +105243298 Gm39259 MGI:MGI:5622144 +105243299 Gm39260 MGI:MGI:5622145 +105243300 LOC105243300 - +105243301 Gm39261 MGI:MGI:5622146 +105243302 Gm39262 MGI:MGI:5622147 +105243303 Gm39263 MGI:MGI:5622148 +105243304 Gm39264 MGI:MGI:5622149 +105243305 Gm39265 MGI:MGI:5622150 +105243306 Gm39266 MGI:MGI:5622151 +105243307 Gm39267 MGI:MGI:5622152 +105243310 Gm39268 MGI:MGI:5622153 +105243311 Gm39269 MGI:MGI:5622154 +105243312 Gm39270 MGI:MGI:5622155 +105243314 Gm39271 MGI:MGI:5622156 +105243315 Gm39272 MGI:MGI:5622157 +105243316 Gm39273 MGI:MGI:5622158 +105243317 Gm39274 MGI:MGI:5622159 +105243318 Gm39275 MGI:MGI:5622160 +105243320 Gm39276 MGI:MGI:5622161 +105243321 Gm39277 MGI:MGI:5622162 +105243322 Gm39278 MGI:MGI:5622163 +105243323 Gm39279 MGI:MGI:5622164 +105243327 Gm39280 MGI:MGI:5622165 +105243328 Gm39281 MGI:MGI:5622166 +105243329 Gm39282 MGI:MGI:5622167 +105243330 Gm39283 MGI:MGI:5622168 +105243331 Gm39284 MGI:MGI:5622169 +105243332 Gm39285 MGI:MGI:5622170 +105243334 Gm39286 MGI:MGI:5622171 +105243335 Gm39287 MGI:MGI:5622172 +105243337 LOC105243337 - +105243339 Gm39288 MGI:MGI:5622173 +105243340 Gm39289 MGI:MGI:5622174 +105243341 Gm39290 MGI:MGI:5622175 +105243343 Gm39291 MGI:MGI:5622176 +105243344 Gm39292 MGI:MGI:5622177 +105243345 Gm39293 MGI:MGI:5622178 +105243346 Gm39294 MGI:MGI:5622179 +105243347 Gm39295 MGI:MGI:5622180 +105243349 Gm39296 MGI:MGI:5622181 +105243350 Gm39297 MGI:MGI:5622182 +105243351 Gm39298 MGI:MGI:5622183 +105243352 Gm39299 MGI:MGI:5622184 +105243353 Gm39300 MGI:MGI:5622185 +105243354 Gm39301 MGI:MGI:5622186 +105243355 Gm39302 MGI:MGI:5622187 +105243356 Gm39303 MGI:MGI:5622188 +105243357 Gm39304 MGI:MGI:5622189 +105243358 Gm39305 MGI:MGI:5622190 +105243359 Gm39306 MGI:MGI:5622191 +105243360 Gm39307 MGI:MGI:5622192 +105243361 Gm39308 MGI:MGI:5622193 +105243362 Gm39309 MGI:MGI:5622194 +105243363 Gm39310 MGI:MGI:5622195 +105243364 Gm39311 MGI:MGI:5622196 +105243366 Gm39312 MGI:MGI:5622197 +105243367 Gm39313 MGI:MGI:5622198 +105243368 Gm39314 MGI:MGI:5622199 +105243369 Gm15521 MGI:MGI:3782968 +105243370 Gm39315 MGI:MGI:5622200 +105243371 Gm39316 MGI:MGI:5622201 +105243373 Gm39317 MGI:MGI:5622202|Ensembl:ENSMUSG00000111056 +105243374 LOC105243374 - +105243376 Gm39318 MGI:MGI:5622203 +105243378 Gm39319 MGI:MGI:5622204 +105243384 Gm39320 MGI:MGI:5622205 +105243385 Gm39321 MGI:MGI:5622206 +105243387 Gm39322 MGI:MGI:5622207 +105243388 Gm39323 MGI:MGI:5622208 +105243389 Gm39324 MGI:MGI:5622209 +105243390 Gm39325 MGI:MGI:5622210 +105243391 Gm39326 MGI:MGI:5622211 +105243393 Gm39327 MGI:MGI:5622212 +105243394 Gm39328 MGI:MGI:5622213 +105243395 Gm39329 MGI:MGI:5622214 +105243396 Gm39330 MGI:MGI:5622215 +105243397 Gm39331 MGI:MGI:5622216 +105243398 Gm39332 MGI:MGI:5622217 +105243400 Gm39333 MGI:MGI:5622218 +105243402 Gm39334 MGI:MGI:5622219 +105243403 Gm39335 MGI:MGI:5622220 +105243404 LOC105243404 - +105243405 Gm39336 MGI:MGI:5622221|Ensembl:ENSMUSG00000111359 +105243406 Gm39337 MGI:MGI:5622222 +105243408 Gm39338 MGI:MGI:5622223 +105243409 Gm39339 MGI:MGI:5622224 +105243410 Gm39340 MGI:MGI:5622225 +105243411 Gm39341 MGI:MGI:5622226 +105243412 Gm39342 MGI:MGI:5622227 +105243414 Gm39343 MGI:MGI:5622228 +105243416 Gm39344 MGI:MGI:5622229 +105243417 Gm39345 MGI:MGI:5622230 +105243419 Gm39346 MGI:MGI:5622231 +105243420 Gm39347 MGI:MGI:5622232 +105243422 Gm39348 MGI:MGI:5622233 +105243423 Gm39349 MGI:MGI:5622234 +105243424 Gm39350 MGI:MGI:5622235 +105243425 Gm39351 MGI:MGI:5622236 +105243426 Gm39352 MGI:MGI:5622237 +105243427 Gm39353 MGI:MGI:5622238 +105243428 Gm39354 MGI:MGI:5622239 +105243429 Gm39355 MGI:MGI:5622240 +105243430 Gm39356 MGI:MGI:5622241 +105243431 Gm39357 MGI:MGI:5622242 +105243432 Gm39358 MGI:MGI:5622243 +105243433 Gm39359 MGI:MGI:5622244 +105243435 Gm39360 MGI:MGI:5622245 +105243436 Gm39361 MGI:MGI:5622246 +105243437 Gm39362 MGI:MGI:5622247 +105243438 Gm39363 MGI:MGI:5622248 +105243439 Gm39364 MGI:MGI:5622249 +105243440 Gm39365 MGI:MGI:5622250 +105243441 Gm39366 MGI:MGI:5622251 +105243443 LOC105243443 - +105243444 LOC105243444 - +105243445 Gm39367 MGI:MGI:5622252 +105243446 Gm39368 MGI:MGI:5622253 +105243447 Gm39369 MGI:MGI:5622254 +105243448 Gm26849 MGI:MGI:5477343 +105243451 Gm27188 MGI:MGI:5521031 +105243452 Gm39370 MGI:MGI:5622255 +105243453 LOC105243453 - +105243455 Gm39371 MGI:MGI:5622256 +105243456 Gm39372 MGI:MGI:5622257 +105243457 Gm39373 MGI:MGI:5622258 +105243458 Gm39374 MGI:MGI:5622259 +105243459 Gm39375 MGI:MGI:5622260 +105243460 Gm39376 MGI:MGI:5622261 +105243461 Gm39377 MGI:MGI:5622262|Ensembl:ENSMUSG00000111633 +105243462 Gm39378 MGI:MGI:5622263 +105243464 Gm39379 MGI:MGI:5622264 +105243465 Gm39380 MGI:MGI:5622265 +105243466 Gm39381 MGI:MGI:5622266 +105243467 Gm39382 MGI:MGI:5622267 +105243468 Gm39383 MGI:MGI:5622268 +105243469 Gm27216 MGI:MGI:5521059|Ensembl:ENSMUSG00000098747 +105243470 Gm39384 MGI:MGI:5622269 +105243471 Gm39385 MGI:MGI:5622270 +105243472 Gm39386 MGI:MGI:5622271 +105243473 Gm39387 MGI:MGI:5622272 +105243474 Gm39388 MGI:MGI:5622273 +105243476 Gm39389 MGI:MGI:5622274 +105243477 Gm39390 MGI:MGI:5622275 +105243482 Gm39391 MGI:MGI:5622276 +105243483 Gm39392 MGI:MGI:5622277 +105243484 Gm11551 MGI:MGI:3649793 +105243485 Gm39393 MGI:MGI:5622278 +105243486 Gm39394 MGI:MGI:5622279 +105243487 Gm11586 MGI:MGI:3652099 +105243489 Gm39395 MGI:MGI:5622280 +105243491 Gm39396 MGI:MGI:5622281 +105243492 Gm39397 MGI:MGI:5622282|Ensembl:ENSMUSG00000110636 +105243494 Gm39398 MGI:MGI:5622283 +105243495 Gm39399 MGI:MGI:5622284 +105243496 Gm39400 MGI:MGI:5622285 +105243499 Gm39401 MGI:MGI:5622286 +105243500 Gm39402 MGI:MGI:5622287 +105243501 Gm39403 MGI:MGI:5622288 +105243502 Gm39404 MGI:MGI:5622289 +105243503 Gm39405 MGI:MGI:5622290 +105243504 Gm39406 MGI:MGI:5622291 +105243505 Gm39407 MGI:MGI:5622292 +105243506 Gm39408 MGI:MGI:5622293 +105243507 Gm39409 MGI:MGI:5622294 +105243508 Gm39410 MGI:MGI:5622295 +105243509 Gm39411 MGI:MGI:5622296 +105243511 Gm37249 MGI:MGI:5610477 +105243512 Gm39412 MGI:MGI:5622297 +105243513 Gm39413 MGI:MGI:5622298 +105243514 LOC105243514 - +105243515 Gm39414 MGI:MGI:5622299 +105243516 Gm28166 MGI:MGI:5578872 +105243517 Gm39415 MGI:MGI:5622300 +105243518 Gm39416 MGI:MGI:5622301 +105243519 Gm39417 MGI:MGI:5622302 +105243520 Gm39418 MGI:MGI:5622303 +105243523 Gm39419 MGI:MGI:5622304 +105243524 Gm39420 MGI:MGI:5622305 +105243525 Gm39421 MGI:MGI:5622306 +105243526 Gm39422 MGI:MGI:5622307 +105243527 Gm17141 MGI:MGI:4937968 +105243528 Gm39423 MGI:MGI:5622308 +105243530 Gm39424 MGI:MGI:5622309 +105243532 Gm39425 MGI:MGI:5622310 +105243533 Gm39426 MGI:MGI:5622311 +105243534 Gm39427 MGI:MGI:5622312 +105243536 Gm39428 MGI:MGI:5622313 +105243537 Gm39429 MGI:MGI:5622314 +105243538 Gm39430 MGI:MGI:5622315 +105243539 Gm39431 MGI:MGI:5622316 +105243540 Gm39432 MGI:MGI:5622317 +105243541 Gm39433 MGI:MGI:5622318 +105243542 Gm39434 MGI:MGI:5622319 +105243543 Gm39435 MGI:MGI:5622320 +105243544 LOC105243544 - +105243545 Gm39436 MGI:MGI:5622321 +105243546 Gm39437 MGI:MGI:5622322 +105243547 Gm39438 MGI:MGI:5622323 +105243548 Gm39439 MGI:MGI:5622324 +105243549 Gm39440 MGI:MGI:5622325 +105243550 Gm39441 MGI:MGI:5622326 +105243551 LOC105243551 - +105243552 Gm39442 MGI:MGI:5622327 +105243553 LOC105243553 - +105243554 Gm39443 MGI:MGI:5622328 +105243555 Gm39444 MGI:MGI:5622329 +105243556 Gm39445 MGI:MGI:5622330 +105243557 Gm39446 MGI:MGI:5622331 +105243558 Gm39447 MGI:MGI:5622332 +105243559 Gm39448 MGI:MGI:5622333 +105243560 Gm39449 MGI:MGI:5622334 +105243561 Gm39450 MGI:MGI:5622335 +105243562 Gm39451 MGI:MGI:5622336 +105243563 Gm39452 MGI:MGI:5622337 +105243565 Gm39453 MGI:MGI:5622338 +105243566 Gm39454 MGI:MGI:5622339 +105243567 Gm39455 MGI:MGI:5622340 +105243569 Gm39456 MGI:MGI:5622341|Ensembl:ENSMUSG00000110760 +105243570 Gm39457 MGI:MGI:5622342 +105243571 Gm39458 MGI:MGI:5622343 +105243572 Gm39459 MGI:MGI:5622344|Ensembl:ENSMUSG00000111720 +105243573 LOC105243573 - +105243574 Gm39460 MGI:MGI:5622345|Ensembl:ENSMUSG00000111528 +105243575 Gm39461 MGI:MGI:5622346 +105243577 Gm39462 MGI:MGI:5622347 +105243578 Gm39463 MGI:MGI:5622348 +105243579 Gm39464 MGI:MGI:5622349 +105243580 Gm39465 MGI:MGI:5622350 +105243581 Gm39466 MGI:MGI:5622351 +105243582 Gm39467 MGI:MGI:5622352 +105243583 Gm39468 MGI:MGI:5622353 +105243585 Gm39469 MGI:MGI:5622354 +105243590 LOC105243590 - +105243592 Gm39470 MGI:MGI:5622355 +105243593 LOC105243593 - +105243594 LOC105243594 - +105243595 LOC105243595 - +105243596 Gm39471 MGI:MGI:5622356 +105243597 Gm39472 MGI:MGI:5622357 +105243599 LOC105243599 - +105243601 Gm39473 MGI:MGI:5622358 +105243604 Gm39474 MGI:MGI:5622359 +105243606 Gm39475 MGI:MGI:5622360 +105243607 Gm39476 MGI:MGI:5622361 +105243608 LOC105243608 - +105243610 Gm39477 MGI:MGI:5622362 +105243612 Gm39478 MGI:MGI:5622363 +105243623 Gm39479 MGI:MGI:5622364 +105243624 Gm39480 MGI:MGI:5622365 +105243627 Gm39481 MGI:MGI:5622366 +105243634 Gm39482 MGI:MGI:5622367 +105243635 LOC105243635 - +105243636 Gm11754 MGI:MGI:3651697 +105243637 Gm11755 MGI:MGI:3651696 +105243642 Gm39483 MGI:MGI:5622368 +105243644 Gm39484 MGI:MGI:5622369 +105243645 Gm39485 MGI:MGI:5622370 +105243646 Gm39486 MGI:MGI:5622371 +105243647 Gm11770 MGI:MGI:3651450 +105243648 Gm39487 MGI:MGI:5622372 +105243649 Gm39488 MGI:MGI:5622373 +105243650 Gm39489 MGI:MGI:5622374 +105243651 Gm39490 MGI:MGI:5622375 +105243653 Gm39491 MGI:MGI:5622376 +105243654 LOC105243654 - +105243655 LOC105243655 - +105243656 Gm39492 MGI:MGI:5622377 +105243657 Gm11775 MGI:MGI:3651517 +105243658 Gm39493 MGI:MGI:5622378 +105243659 Gm39494 MGI:MGI:5622379 +105243660 Gm39495 MGI:MGI:5622380 +105243661 Gm39496 MGI:MGI:5622381 +105243665 LOC105243665 - +105243666 Gm39497 MGI:MGI:5622382 +105243667 Gm39498 MGI:MGI:5622383 +105243668 Gm39499 MGI:MGI:5622384 +105243669 Gm39500 MGI:MGI:5622385 +105243670 Gm39501 MGI:MGI:5622386 +105243671 Gm39502 MGI:MGI:5622387 +105243672 Gm39503 MGI:MGI:5622388 +105243673 Gm39504 MGI:MGI:5622389 +105243674 Gm39505 MGI:MGI:5622390 +105243675 Gm39506 MGI:MGI:5622391 +105243676 Gm39507 MGI:MGI:5622392 +105243677 Gm39508 MGI:MGI:5622393 +105243678 Gm39509 MGI:MGI:5622394 +105243679 Gm39510 MGI:MGI:5622395 +105243680 Gm39511 MGI:MGI:5622396 +105243681 Gm39512 MGI:MGI:5622397 +105243682 Gm39513 MGI:MGI:5622398 +105243684 Gm39514 MGI:MGI:5622399 +105243685 Gm39515 MGI:MGI:5622400 +105243686 Gm39516 MGI:MGI:5622401 +105243687 Gm39517 MGI:MGI:5622402 +105243688 Gm39518 MGI:MGI:5622403 +105243691 Gm39519 MGI:MGI:5622404 +105243692 Gm39520 MGI:MGI:5622405 +105243693 Gm39521 MGI:MGI:5622406 +105243695 Gm39522 MGI:MGI:5622407 +105243696 Gm15063 MGI:MGI:3705169 +105243697 Gm14707 MGI:MGI:3705259 +105243698 Gm39523 MGI:MGI:5622408 +105243699 LOC105243699 - +105243700 Gm39524 MGI:MGI:5622409 +105243701 LOC105243701 - +105243702 Gm39525 MGI:MGI:5622410 +105243703 Gm14830 MGI:MGI:3705386 +105243704 Gm39526 MGI:MGI:5622411 +105243706 Gm39527 MGI:MGI:5622412 +105243708 Gm39528 MGI:MGI:5622413 +105243709 Gm14809 MGI:MGI:3705177 +105243711 LOC105243711 - +105243712 Gm39529 MGI:MGI:5622414 +105243714 Gm39530 MGI:MGI:5622415 +105243715 Gm39531 MGI:MGI:5622416 +105243716 Gm39532 MGI:MGI:5622417 +105243719 Gm39533 MGI:MGI:5622418 +105243720 Gm39534 MGI:MGI:5622419 +105243722 Gm39535 MGI:MGI:5622420 +105243723 Gm39536 MGI:MGI:5622421 +105243724 Gm39537 MGI:MGI:5622422 +105243725 Gm39538 MGI:MGI:5622423 +105243726 Gm39539 MGI:MGI:5622424 +105243727 Gm4995 MGI:MGI:3643395 +105243729 Gm39540 MGI:MGI:5622425 +105243730 Gm39541 MGI:MGI:5622426 +105243731 Gm39542 MGI:MGI:5622427 +105243732 Gm39543 MGI:MGI:5622428 +105243734 Gm39544 MGI:MGI:5622429 +105243735 Gm39545 MGI:MGI:5622430 +105243737 Gm15169 MGI:MGI:3705215 +105243738 Gm39546 MGI:MGI:5622431 +105243739 Gm39547 MGI:MGI:5622432 +105243740 Gm39548 MGI:MGI:5622433 +105243741 LOC105243741 - +105243742 Gm39549 MGI:MGI:5622434 +105243743 Gm39550 MGI:MGI:5622435 +105243744 Gm39551 MGI:MGI:5622436 +105243746 Gm39552 MGI:MGI:5622437 +105243747 Gm39553 MGI:MGI:5622438 +105243748 Gm39554 MGI:MGI:5622439 +105243749 Gm39555 MGI:MGI:5622440 +105243761 Gm39556 MGI:MGI:5622441 +105243765 Gm39557 MGI:MGI:5622442 +105243769 Gm39558 MGI:MGI:5622443 +105243774 Gm39559 MGI:MGI:5622444 +105243775 Gm39560 MGI:MGI:5622445 +105243776 Gm39561 MGI:MGI:5622446 +105243777 Gm39562 MGI:MGI:5622447 +105243781 LOC105243781 - +105243782 Gm39563 MGI:MGI:5622448 +105243785 LOC105243785 - +105243789 LOC105243789 - +105243790 Gm39564 MGI:MGI:5622449 +105243791 Gm39565 MGI:MGI:5622450 +105243794 Gm39566 MGI:MGI:5622451|Ensembl:ENSMUSG00000109737|Vega:OTTMUSG00000060508 +105243797 Gm39567 MGI:MGI:5622452 +105243798 Gm39568 MGI:MGI:5622453 +105243800 Gm39569 MGI:MGI:5622454 +105243802 Gm39570 MGI:MGI:5622455 +105243804 Gm39571 MGI:MGI:5622456 +105243808 Gm39572 MGI:MGI:5622457 +105243814 Gm39573 MGI:MGI:5622458 +105243816 LOC105243816 - +105243821 Gm39574 MGI:MGI:5622459 +105243825 Gm39575 MGI:MGI:5622460 +105243826 LOC105243826 - +105243828 Gm39576 MGI:MGI:5622461 +105243832 Gm39577 MGI:MGI:5622462 +105243834 Gm39578 MGI:MGI:5622463 +105243837 Gm39579 MGI:MGI:5622464 +105243841 Gm39580 MGI:MGI:5622465 +105243848 Gm39581 MGI:MGI:5622466 +105243849 Gm39582 MGI:MGI:5622467 +105243850 Gm39583 MGI:MGI:5622468 +105243851 Gm12909 MGI:MGI:3651135|Ensembl:ENSMUSG00000085404 +105243852 Gm39584 MGI:MGI:5622469 +105243853 Gm39585 MGI:MGI:5622470 +105243854 Gm39586 MGI:MGI:5622471 +105243855 Gm37323 MGI:MGI:5610551 +105243856 Gm39587 MGI:MGI:5622472 +105243857 Gm39588 MGI:MGI:5622473 +105243858 Gm39589 MGI:MGI:5622474 +105243859 Gm39590 MGI:MGI:5622475 +105243860 Gm39591 MGI:MGI:5622476 +105243861 Gm39592 MGI:MGI:5622477 +105243862 Gm39593 MGI:MGI:5622478 +105243863 Gm39594 MGI:MGI:5622479 +105243864 Gm39595 MGI:MGI:5622480 +105243865 Gm39596 MGI:MGI:5622481 +105243866 LOC105243866 - +105243867 Gm39597 MGI:MGI:5622482 +105243868 Gm28153 MGI:MGI:5578859 +105243869 Gm39598 MGI:MGI:5622483 +105243870 Gm28340 MGI:MGI:5579046 +105243871 Gm39599 MGI:MGI:5622484 +105243872 Gm39600 MGI:MGI:5622485 +105243874 Gm28401 MGI:MGI:5579107 +105243875 Gm39601 MGI:MGI:5622486 +105243876 Gm39602 MGI:MGI:5622487 +105243877 Gm39603 MGI:MGI:5622488 +105243878 Gm12031 MGI:MGI:3651406 +105243879 Gm39604 MGI:MGI:5622489 +105243880 Gm39605 MGI:MGI:5622490 +105243881 Gm39606 MGI:MGI:5622491 +105243882 Gm39607 MGI:MGI:5622492 +105243883 Gm39608 MGI:MGI:5622493 +105243884 Gm39609 MGI:MGI:5622494 +105243885 Gm39610 MGI:MGI:5622495 +105243886 Gm39611 MGI:MGI:5622496 +105243887 Gm39612 MGI:MGI:5622497 +105243888 Gm12061 MGI:MGI:3651662 +105243889 Gm39613 MGI:MGI:5622498 +105243890 Gm28822 MGI:MGI:5579528 +105243891 Gm26524 MGI:MGI:5477018 +105243892 Gm29414 MGI:MGI:5580120 +105243893 Gm39614 MGI:MGI:5622499 +105243894 Gm39615 MGI:MGI:5622500 +105243895 Gm39616 MGI:MGI:5622501 +105243896 Gm39617 MGI:MGI:5622502 +105243897 Gm39618 MGI:MGI:5622503 +105243898 Gm39619 MGI:MGI:5622504 +105243899 Gm39620 MGI:MGI:5622505 +105243900 Gm39621 MGI:MGI:5622506 +105243901 Gm39622 MGI:MGI:5622507 +105243902 Gm39623 MGI:MGI:5622508 +105243903 Gm39624 MGI:MGI:5622509 +105243904 Gm39625 MGI:MGI:5622510 +105243905 Gm37020 MGI:MGI:5610248 +105243906 Gm39626 MGI:MGI:5622511 +105243907 Gm39627 MGI:MGI:5622512 +105243908 Gm39628 MGI:MGI:5622513 +105243909 Gm39629 MGI:MGI:5622514 +105243910 LOC105243910 - +105243911 Gm39630 MGI:MGI:5622515 +105243912 Gm39631 MGI:MGI:5622516 +105243913 Gm39632 MGI:MGI:5622517 +105243914 Gm39633 MGI:MGI:5622518 +105243915 Gm28782 MGI:MGI:5579488 +105243916 Gm39634 MGI:MGI:5622519 +105243917 Gm28893 MGI:MGI:5579599 +105243918 Gm39635 MGI:MGI:5622520 +105243919 Gm39636 MGI:MGI:5622521 +105243920 Gm39637 MGI:MGI:5622522 +105243921 Gm39638 MGI:MGI:5622523 +105243922 Gm39639 MGI:MGI:5622524 +105243923 Gm39640 MGI:MGI:5622525 +105243924 Gm39641 MGI:MGI:5622526 +105243925 Gm28777 MGI:MGI:5579483 +105243926 Gm39642 MGI:MGI:5622527 +105243927 LOC105243927 - +105243928 Gm39643 MGI:MGI:5622528 +105243929 Gm39644 MGI:MGI:5622529 +105243930 Gm39645 MGI:MGI:5622530 +105243931 Gm39646 MGI:MGI:5622531 +105243932 Gm29018 MGI:MGI:5579724 +105243933 Gm39647 MGI:MGI:5622532 +105243934 Gm39648 MGI:MGI:5622533 +105243935 Gm39649 MGI:MGI:5622534 +105243936 Gm38388 MGI:MGI:5613624 +105243937 Gm39650 MGI:MGI:5622535 +105243938 Gm38137 MGI:MGI:5611365 +105243939 LOC105243939 - +105243940 Pard3bos2 MGI:MGI:3650411 +105243941 Gm39651 MGI:MGI:5622536 +105243942 Gm29083 MGI:MGI:5579789 +105243943 Gm39652 MGI:MGI:5622537 +105243944 Gm39653 MGI:MGI:5622538 +105243945 Gm39654 MGI:MGI:5622539 +105243946 Gm38058 MGI:MGI:5611286 +105243947 Gm39655 MGI:MGI:5622540 +105243948 Gm39656 MGI:MGI:5622541 +105243949 Gm39657 MGI:MGI:5622542 +105243950 Gm39658 MGI:MGI:5622543 +105243951 Gm15669 MGI:MGI:3783111 +105243952 Gm39659 MGI:MGI:5622544 +105243953 Gm39660 MGI:MGI:5622545 +105243954 Gm39661 MGI:MGI:5622546 +105243955 Gm39662 MGI:MGI:5622547 +105243956 Gm39663 MGI:MGI:5622548 +105243957 Gm29185 MGI:MGI:5579891 +105243958 Gm39664 MGI:MGI:5622549 +105243959 Gm39665 MGI:MGI:5622550 +105243960 Gm39666 MGI:MGI:5622551 +105243961 Gm39667 MGI:MGI:5622552 +105243962 Gm39668 MGI:MGI:5622553 +105243964 LOC105243964 - +105243965 Gm39669 MGI:MGI:5622554 +105243968 LOC105243968 - +105243969 Gm39670 MGI:MGI:5622555 +105243970 Gm39671 MGI:MGI:5622556 +105243972 Gm39672 MGI:MGI:5622557 +105243973 Gm39673 MGI:MGI:5622558 +105243974 Gm39674 MGI:MGI:5622559 +105243975 Gm39675 MGI:MGI:5622560 +105243976 Gm39676 MGI:MGI:5622561 +105243978 Gm39677 MGI:MGI:5622562 +105243979 Gm39678 MGI:MGI:5622563 +105243980 Gm39679 MGI:MGI:5622564 +105243981 Gm39680 MGI:MGI:5622565 +105243982 Gm39681 MGI:MGI:5622566 +105243983 Gm39682 MGI:MGI:5622567 +105243984 Gm39683 MGI:MGI:5622568 +105243985 Gm39684 MGI:MGI:5622569 +105243986 Gm37943 MGI:MGI:5611171 +105243987 Gm39685 MGI:MGI:5622570 +105243989 Gm39686 MGI:MGI:5622571 +105243990 Gm39687 MGI:MGI:5622572 +105243991 Gm37294 MGI:MGI:5610522 +105243992 Gm39688 MGI:MGI:5622573 +105243993 Gm20471 MGI:MGI:5141936 +105243994 Gm39689 MGI:MGI:5622574 +105243995 Gm39690 MGI:MGI:5622575 +105243996 Gm39691 MGI:MGI:5622576 +105243997 Gm39692 MGI:MGI:5622577 +105243998 Gm39693 MGI:MGI:5622578 +105243999 Gm39694 MGI:MGI:5622579 +105244000 Gm39695 MGI:MGI:5622580 +105244001 Gm39696 MGI:MGI:5622581 +105244002 Gm39697 MGI:MGI:5622582 +105244003 Gm39698 MGI:MGI:5622583 +105244004 Gm39699 MGI:MGI:5622584 +105244005 Gm39700 MGI:MGI:5622585 +105244006 Gm39701 MGI:MGI:5622586 +105244007 LOC105244007 - +105244008 Gm39702 MGI:MGI:5622587 +105244009 Gm39703 MGI:MGI:5622588 +105244010 Gm37065 MGI:MGI:5610293 +105244011 Gm39704 MGI:MGI:5622589 +105244012 Gm37125 MGI:MGI:5610353 +105244013 Gm39705 MGI:MGI:5622590 +105244014 Gm39706 MGI:MGI:5622591 +105244015 Gm39707 MGI:MGI:5622592 +105244016 Gm39708 MGI:MGI:5622593 +105244017 Gm37486 MGI:MGI:5610714 +105244018 Gm39709 MGI:MGI:5622594 +105244019 LOC105244019 - +105244020 Gm39710 MGI:MGI:5622595 +105244021 Gm39711 MGI:MGI:5622596 +105244022 Gm38331 MGI:MGI:5611559 +105244023 Gm37336 MGI:MGI:5610564 +105244024 Gm39712 MGI:MGI:5622597 +105244025 Gm39713 MGI:MGI:5622598 +105244026 Gm38293 MGI:MGI:5611521 +105244027 Gm39714 MGI:MGI:5622599 +105244028 Gm39715 MGI:MGI:5622600 +105244029 Gm37406 MGI:MGI:5610634 +105244030 Gm39716 MGI:MGI:5622601 +105244031 Gm39717 MGI:MGI:5622602 +105244032 Gm39718 MGI:MGI:5622603 +105244033 Gm39719 MGI:MGI:5622604 +105244034 LOC105244034 - +105244035 Gm39720 MGI:MGI:5622605 +105244036 Gm39721 MGI:MGI:5622606 +105244037 Gm39722 MGI:MGI:5622607 +105244038 Gm39723 MGI:MGI:5622608 +105244040 Gm39724 MGI:MGI:5622609 +105244041 Gm39725 MGI:MGI:5622610 +105244042 Gm39726 MGI:MGI:5622611 +105244043 Gm39727 MGI:MGI:5622612 +105244044 Gm39728 MGI:MGI:5622613 +105244045 Gm37662 MGI:MGI:5610890 +105244046 Gm39729 MGI:MGI:5622614 +105244047 Gm39730 MGI:MGI:5622615 +105244048 Gm39731 MGI:MGI:5622616 +105244049 Gm39732 MGI:MGI:5622617 +105244050 Gm15509 MGI:MGI:3782957 +105244051 Gm39733 MGI:MGI:5622618 +105244052 Gm39734 MGI:MGI:5622619 +105244053 Gm39735 MGI:MGI:5622620 +105244054 Gm39736 MGI:MGI:5622621 +105244055 Gm39737 MGI:MGI:5622622 +105244056 Gm39738 MGI:MGI:5622623 +105244057 Gm39739 MGI:MGI:5622624 +105244058 Gm39740 MGI:MGI:5622625 +105244059 LOC105244059 - +105244060 Gm39741 MGI:MGI:5622626 +105244062 Gm39742 MGI:MGI:5622627 +105244063 Gm39743 MGI:MGI:5622628 +105244064 Gm26670 MGI:MGI:5477164 +105244065 Gm39744 MGI:MGI:5622629 +105244066 Gm39745 MGI:MGI:5622630 +105244068 Gm39746 MGI:MGI:5622631 +105244069 Gm39747 MGI:MGI:5622632 +105244070 Gm39748 MGI:MGI:5622633 +105244071 Gm39749 MGI:MGI:5622634 +105244072 Gm39750 MGI:MGI:5622635 +105244073 Gm39751 MGI:MGI:5622636 +105244074 Gm39752 MGI:MGI:5622637 +105244075 Gm39753 MGI:MGI:5622638 +105244076 Gm39754 MGI:MGI:5622639 +105244077 Gm39755 MGI:MGI:5622640 +105244078 Gm39756 MGI:MGI:5622641 +105244079 Gm39757 MGI:MGI:5622642 +105244080 LOC105244080 - +105244081 Gm39758 MGI:MGI:5622643 +105244082 Gm39759 MGI:MGI:5622644 +105244083 Gm39760 MGI:MGI:5622645 +105244084 Gm13270 MGI:MGI:3651704 +105244085 LOC105244085 - +105244086 Gm37416 MGI:MGI:5610644 +105244087 Gm39761 MGI:MGI:5622646 +105244088 Gm39762 MGI:MGI:5622647 +105244089 Gm39763 MGI:MGI:5622648 +105244090 Gm39764 MGI:MGI:5622649 +105244091 Gm39765 MGI:MGI:5622650 +105244092 Gm39766 MGI:MGI:5622651 +105244093 Gm39767 MGI:MGI:5622652 +105244094 Gm39768 MGI:MGI:5622653 +105244095 Gm39769 MGI:MGI:5622654 +105244096 Gm39770 MGI:MGI:5622655 +105244097 Gm39771 MGI:MGI:5622656 +105244098 Gm39772 MGI:MGI:5622657 +105244099 Gm39773 MGI:MGI:5622658 +105244100 Gm39774 MGI:MGI:5622659 +105244101 Gm39775 MGI:MGI:5622660 +105244102 LOC105244102 - +105244103 Gm39776 MGI:MGI:5622661 +105244104 Gm39777 MGI:MGI:5622662 +105244105 Gm39778 MGI:MGI:5622663 +105244106 Gm39779 MGI:MGI:5622664 +105244107 Gm39780 MGI:MGI:5622665 +105244108 Gm39781 MGI:MGI:5622666 +105244109 Gm39782 MGI:MGI:5622667 +105244110 Gm39783 MGI:MGI:5622668 +105244111 Gm39784 MGI:MGI:5622669 +105244112 Gm39785 MGI:MGI:5622670 +105244113 Gm39786 MGI:MGI:5622671 +105244114 Gm13610 MGI:MGI:3651297 +105244115 Gm39787 MGI:MGI:5622672 +105244116 Gm39788 MGI:MGI:5622673 +105244117 Gm13524 MGI:MGI:3651427 +105244118 Gm13528 MGI:MGI:3651630 +105244119 Gm13536 MGI:MGI:3651924 +105244120 Gm39789 MGI:MGI:5622674 +105244121 Gm39790 MGI:MGI:5622675 +105244122 Gm39791 MGI:MGI:5622676 +105244123 Gm39792 MGI:MGI:5622677 +105244124 LOC105244124 - +105244125 Gm39793 MGI:MGI:5622678 +105244126 Gm39794 MGI:MGI:5622679 +105244127 Gm39795 MGI:MGI:5622680 +105244128 Gm39796 MGI:MGI:5622681 +105244129 Gm39797 MGI:MGI:5622682 +105244130 Gm39798 MGI:MGI:5622683 +105244131 Gm13428 MGI:MGI:3649767 +105244132 Gm39799 MGI:MGI:5622684 +105244133 Gm39800 MGI:MGI:5622685 +105244134 Gm39801 MGI:MGI:5622686 +105244135 Gm39802 MGI:MGI:5622687 +105244136 Gm39803 MGI:MGI:5622688 +105244137 Gm39804 MGI:MGI:5622689 +105244138 Gm39805 MGI:MGI:5622690 +105244139 Gm39806 MGI:MGI:5622691 +105244140 Gm39807 MGI:MGI:5622692 +105244141 Gm39808 MGI:MGI:5622693 +105244142 Gm39809 MGI:MGI:5622694 +105244143 Gm39810 MGI:MGI:5622695 +105244144 Gm13480 MGI:MGI:3651871 +105244145 Gm13485 MGI:MGI:3651421 +105244146 Gm39811 MGI:MGI:5622696 +105244147 Gm39812 MGI:MGI:5622697 +105244149 Gm39813 MGI:MGI:5622698 +105244150 LOC105244150 - +105244151 LOC105244151 - +105244152 Gm39814 MGI:MGI:5622699 +105244153 Gm39815 MGI:MGI:5622700 +105244154 Gm39816 MGI:MGI:5622701 +105244156 Gm39817 MGI:MGI:5622702 +105244157 Gm39818 MGI:MGI:5622703 +105244158 LOC105244158 - +105244159 Gm39819 MGI:MGI:5622704 +105244160 Gm39820 MGI:MGI:5622705 +105244161 Gm39821 MGI:MGI:5622706 +105244162 Gm39822 MGI:MGI:5622707|Ensembl:ENSMUSG00000110618 +105244164 LOC105244164 - +105244165 Gm39823 MGI:MGI:5622708 +105244166 Gm39824 MGI:MGI:5622709 +105244167 Gm39825 MGI:MGI:5622710 +105244168 Gm12227 MGI:MGI:3649740 +105244170 LOC105244170 - +105244171 Gm12240 MGI:MGI:3649325 +105244172 Gm39826 MGI:MGI:5622711 +105244173 Gm39827 MGI:MGI:5622712 +105244174 Gm39828 MGI:MGI:5622713 +105244176 Gm39829 MGI:MGI:5622714 +105244177 Gm39830 MGI:MGI:5622715 +105244178 Gm39831 MGI:MGI:5622716 +105244179 Gm39832 MGI:MGI:5622717 +105244180 Gm39833 MGI:MGI:5622718 +105244181 Gm39834 MGI:MGI:5622719 +105244182 Gm39835 MGI:MGI:5622720 +105244183 Gm39836 MGI:MGI:5622721 +105244184 Gm39837 MGI:MGI:5622722 +105244185 Gm39838 MGI:MGI:5622723 +105244186 Gm39839 MGI:MGI:5622724 +105244187 LOC105244187 - +105244188 Gm39840 MGI:MGI:5622725 +105244189 Gm39841 MGI:MGI:5622726 +105244190 Gm39842 MGI:MGI:5622727 +105244191 Gm39843 MGI:MGI:5622728 +105244192 Gm39844 MGI:MGI:5622729 +105244193 LOC105244193 - +105244194 Gm39845 MGI:MGI:5622730 +105244195 LOC105244195 - +105244196 Gm39846 MGI:MGI:5622731 +105244197 Gm39847 MGI:MGI:5622732 +105244198 Gm39848 MGI:MGI:5622733 +105244199 Gm39849 MGI:MGI:5622734 +105244200 Gm39850 MGI:MGI:5622735 +105244201 Gm39851 MGI:MGI:5622736 +105244202 Gm39852 MGI:MGI:5622737 +105244203 Gm39853 MGI:MGI:5622738 +105244204 Gm39854 MGI:MGI:5622739 +105244205 Gm39855 MGI:MGI:5622740 +105244206 Gm39856 MGI:MGI:5622741 +105244207 Gm39857 MGI:MGI:5622742 +105244208 LOC105244208 - +105244209 Gm39858 MGI:MGI:5622743 +105244210 Gm39859 MGI:MGI:5622744 +105244212 Gm39860 MGI:MGI:5622745 +105244213 Gm39861 MGI:MGI:5622746 +105244214 Gm39862 MGI:MGI:5622747 +105244215 Gm39863 MGI:MGI:5622748 +105244216 Gm39864 MGI:MGI:5622749 +105244217 Gm39865 MGI:MGI:5622750 +105244218 Gm39866 MGI:MGI:5622751 +105244219 Gm39867 MGI:MGI:5622752 +105244221 Gm39868 MGI:MGI:5622753 +105244222 Gm39869 MGI:MGI:5622754 +105244223 Gm39870 MGI:MGI:5622755 +105244224 Gm39871 MGI:MGI:5622756 +105244225 Gm39872 MGI:MGI:5622757 +105244226 Gm39873 MGI:MGI:5622758 +105244227 Gm39874 MGI:MGI:5622759 +105244228 Gm39875 MGI:MGI:5622760 +105244229 Gm39876 MGI:MGI:5622761 +105244230 Gm39877 MGI:MGI:5622762 +105244231 Gm39878 MGI:MGI:5622763 +105244232 LOC105244232 - +105244233 Gm39879 MGI:MGI:5622764 +105244234 Gm13814 MGI:MGI:3649319 +105244235 Gm13816 MGI:MGI:3649317 +105244236 Gm39880 MGI:MGI:5622765 +105244237 LOC105244237 - +105244238 Gm39881 MGI:MGI:5622766 +105244239 Gm39882 MGI:MGI:5622767 +105244240 Gm39883 MGI:MGI:5622768 +105244241 Gm39884 MGI:MGI:5622769 +105244242 Gm39885 MGI:MGI:5622770 +105244243 Gm39886 MGI:MGI:5622771 +105244244 Gm39887 MGI:MGI:5622772 +105244245 Gm39888 MGI:MGI:5622773 +105244246 Gm39889 MGI:MGI:5622774 +105244247 Gm39890 MGI:MGI:5622775 +105244248 Gm39891 MGI:MGI:5622776 +105244249 Gm39892 MGI:MGI:5622777 +105244250 Gm39893 MGI:MGI:5622778 +105244251 LOC105244251 - +105244252 Gm39894 MGI:MGI:5622779 +105244253 Gm39895 MGI:MGI:5622780 +105244254 Gm39896 MGI:MGI:5622781 +105244255 Gm39897 MGI:MGI:5622782 +105244256 Gm39898 MGI:MGI:5622783 +105244257 Gm39899 MGI:MGI:5622784 +105244258 Gm39900 MGI:MGI:5622785 +105244259 LOC105244259 - +105244260 Gm39901 MGI:MGI:5622786 +105244261 Gm39902 MGI:MGI:5622787 +105244262 Gm39903 MGI:MGI:5622788 +105244263 Gm39904 MGI:MGI:5622789 +105244264 Gm39905 MGI:MGI:5622790 +105244265 Gm39906 MGI:MGI:5622791 +105244266 Gm39907 MGI:MGI:5622792 +105244267 Gm39908 MGI:MGI:5622793 +105244268 Gm39909 MGI:MGI:5622794 +105244269 Gm39910 MGI:MGI:5622795 +105244270 Gm39911 MGI:MGI:5622796 +105244271 Gm39912 MGI:MGI:5622797 +105244272 Gm39913 MGI:MGI:5622798 +105244273 Gm39914 MGI:MGI:5622799 +105244274 Gm39915 MGI:MGI:5622800 +105244276 Gm39916 MGI:MGI:5622801 +105244277 Gm39917 MGI:MGI:5622802 +105244278 Gm39918 MGI:MGI:5622803 +105244279 Gm39919 MGI:MGI:5622804 +105244280 Gm39920 MGI:MGI:5622805 +105244281 Gm39921 MGI:MGI:5622806 +105244282 Gm27003 MGI:MGI:5504118 +105244283 Gm39922 MGI:MGI:5622807 +105244284 Gm39923 MGI:MGI:5622808 +105244285 Gm39924 MGI:MGI:5622809 +105244286 Gm39925 MGI:MGI:5622810 +105244287 Gm39926 MGI:MGI:5622811 +105244288 Gm39927 MGI:MGI:5622812 +105244289 Gm39928 MGI:MGI:5622813 +105244290 Gm39929 MGI:MGI:5622814 +105244291 Gm39930 MGI:MGI:5622815 +105244292 Gm39931 MGI:MGI:5622816 +105244293 Gm39932 MGI:MGI:5622817 +105244294 Gm39933 MGI:MGI:5622818 +105244295 Gm39934 MGI:MGI:5622819 +105244296 Gm39935 MGI:MGI:5622820 +105244297 Gm39936 MGI:MGI:5622821 +105244298 Gm14042 MGI:MGI:3650956 +105244299 Gm39937 MGI:MGI:5622822 +105244300 Gm14304 MGI:MGI:3650849 +105244301 Gm39938 MGI:MGI:5622823 +105244302 Gm39939 MGI:MGI:5622824 +105244303 Gm14095 MGI:MGI:3651962 +105244304 Gm14100 MGI:MGI:3651733 +105244305 Gm39940 MGI:MGI:5622825 +105244306 Gm39941 MGI:MGI:5622826 +105244307 Gm39942 MGI:MGI:5622827 +105244309 Gm39943 MGI:MGI:5622828 +105244310 Gm39944 MGI:MGI:5622829 +105244311 Gm39945 MGI:MGI:5622830 +105244312 Gm39946 MGI:MGI:5622831 +105244313 Gm39947 MGI:MGI:5622832 +105244314 Gm39948 MGI:MGI:5622833 +105244315 Gm39949 MGI:MGI:5622834 +105244316 Gm39950 MGI:MGI:5622835 +105244317 Gm39951 MGI:MGI:5622836 +105244318 Gm39952 MGI:MGI:5622837 +105244319 Gm39953 MGI:MGI:5622838 +105244320 Gm39954 MGI:MGI:5622839 +105244321 Gm39955 MGI:MGI:5622840 +105244322 Gm39956 MGI:MGI:5622841 +105244323 Gm39957 MGI:MGI:5622842 +105244325 Gm39958 MGI:MGI:5622843 +105244326 Gm39959 MGI:MGI:5622844 +105244327 Gm39960 MGI:MGI:5622845 +105244328 Gm14161 MGI:MGI:3649234 +105244329 Gm14199 MGI:MGI:3651370 +105244330 Gm39961 MGI:MGI:5622846 +105244331 Gm39962 MGI:MGI:5622847 +105244332 Gm39963 MGI:MGI:5622848 +105244333 LOC105244333 - +105244334 Gm39964 MGI:MGI:5622849 +105244335 Gm39965 MGI:MGI:5622850 +105244336 Gm39966 MGI:MGI:5622851 +105244337 Gm39967 MGI:MGI:5622852 +105244338 LOC105244338 - +105244339 Gm39968 MGI:MGI:5622853 +105244340 Gm39969 MGI:MGI:5622854 +105244341 Gm39970 MGI:MGI:5622855 +105244342 Gm39971 MGI:MGI:5622856 +105244343 Gm39972 MGI:MGI:5622857 +105244344 Gm39973 MGI:MGI:5622858 +105244345 LOC105244345 - +105244346 Gm39974 MGI:MGI:5622859 +105244347 Gm39975 MGI:MGI:5622860 +105244348 Gm14221 MGI:MGI:3650696 +105244350 Gm39976 MGI:MGI:5622861 +105244351 Gm39977 MGI:MGI:5622862 +105244352 Gm39978 MGI:MGI:5622863 +105244353 Gm39979 MGI:MGI:5622864 +105244354 Gm11457 MGI:MGI:3705139 +105244355 Gm39980 MGI:MGI:5622865 +105244356 Gm39981 MGI:MGI:5622866 +105244357 1810021M19Rik MGI:MGI:1916369 +105244358 Gm39982 MGI:MGI:5622867 +105244359 Gm14268 MGI:MGI:3649848 +105244360 Gm39983 MGI:MGI:5622868 +105244361 Gm39984 MGI:MGI:5622869 +105244362 Gm39985 MGI:MGI:5622870 +105244363 Gm39986 MGI:MGI:5622871 +105244364 Gm39987 MGI:MGI:5622872 +105244365 Gm39988 MGI:MGI:5622873 +105244366 Gm39989 MGI:MGI:5622874 +105244367 Gm39990 MGI:MGI:5622875 +105244368 Gm39991 MGI:MGI:5622876 +105244369 Gm39992 MGI:MGI:5622877 +105244370 Gm14261 MGI:MGI:3649583 +105244371 Gm39993 MGI:MGI:5622878 +105244373 Gm39994 MGI:MGI:5622879 +105244374 Gm14250 MGI:MGI:3650579|Ensembl:ENSMUSG00000086840 +105244375 Zfp286os MGI:MGI:3650267 +105244376 Gm39995 MGI:MGI:5622880 +105244377 Gm39996 MGI:MGI:5622881 +105244378 Gm39997 MGI:MGI:5622882 +105244379 Gm39998 MGI:MGI:5622883 +105244380 Gm39999 MGI:MGI:5622884 +105244381 Gm40000 MGI:MGI:5622885 +105244382 Gm40001 MGI:MGI:5622886 +105244383 Gm40002 MGI:MGI:5622887 +105244384 Gm40003 MGI:MGI:5622888 +105244385 Gm40004 MGI:MGI:5622889 +105244386 Gm40005 MGI:MGI:5622890 +105244387 Gm40006 MGI:MGI:5622891 +105244388 Gm40007 MGI:MGI:5622892 +105244389 Gm40008 MGI:MGI:5622893 +105244390 Gm40009 MGI:MGI:5622894 +105244391 Gm40010 MGI:MGI:5622895 +105244392 Gm40011 MGI:MGI:5622896 +105244393 Gm40012 MGI:MGI:5622897 +105244394 Gm40013 MGI:MGI:5622898 +105244396 Gm40014 MGI:MGI:5622899 +105244397 Gm40015 MGI:MGI:5622900 +105244398 LOC105244398 - +105244400 Gm40016 MGI:MGI:5622901 +105244401 Gm14444 MGI:MGI:3652325 +105244402 LOC105244402 - +105244403 Gm40017 MGI:MGI:5622902 +105244404 Gm40018 MGI:MGI:5622903 +105244406 Gm40019 MGI:MGI:5622904 +105244407 Gm40020 MGI:MGI:5622905 +105244408 Gm40021 MGI:MGI:5622906 +105244409 Gm40022 MGI:MGI:5622907 +105244410 Gm40023 MGI:MGI:5622908 +105244412 Gm40024 MGI:MGI:5622909 +105244413 LOC105244413 - +105244414 Gm40025 MGI:MGI:5622910 +105244415 Gm40026 MGI:MGI:5622911 +105244416 LOC105244416 - +105244417 Gm40027 MGI:MGI:5622912 +105244418 Gm40028 MGI:MGI:5622913 +105244419 Gm12299 MGI:MGI:3652304 +105244420 Gm40029 MGI:MGI:5622914 +105244421 Gm40030 MGI:MGI:5622915 +105244422 Gm40031 MGI:MGI:5622916 +105244423 Gm40032 MGI:MGI:5622917 +105244424 Gm40033 MGI:MGI:5622918 +105244425 Gm40034 MGI:MGI:5622919 +105244426 Gm40035 MGI:MGI:5622920 +105244427 Gm40036 MGI:MGI:5622921 +105244428 Gm40037 MGI:MGI:5622922 +105244429 Gm40038 MGI:MGI:5622923 +105244430 Gm40039 MGI:MGI:5622924 +105244431 Gm40040 MGI:MGI:5622925 +105244432 Gm40041 MGI:MGI:5622926 +105244433 LOC105244433 - +105244434 Gm40042 MGI:MGI:5622927 +105244435 Gm40043 MGI:MGI:5622928 +105244436 Gm37548 MGI:MGI:5610776 +105244437 Gm40044 MGI:MGI:5622929 +105244438 Gm40045 MGI:MGI:5622930 +105244439 Gm40046 MGI:MGI:5622931 +105244440 Gm40047 MGI:MGI:5622932 +105244441 Gm40048 MGI:MGI:5622933 +105244442 Gm40049 MGI:MGI:5622934 +105244443 Gm40050 MGI:MGI:5622935 +105244444 Gm40051 MGI:MGI:5622936 +105244445 Gm40052 MGI:MGI:5622937 +105244446 Gm40053 MGI:MGI:5622938 +105244447 Gm40054 MGI:MGI:5622939 +105244448 LOC105244448 - +105244449 Gm40055 MGI:MGI:5622940 +105244450 Gm40056 MGI:MGI:5622941 +105244451 Gm40057 MGI:MGI:5622942 +105244452 Gm40058 MGI:MGI:5622943 +105244453 Gm40059 MGI:MGI:5622944 +105244454 Gm40060 MGI:MGI:5622945 +105244455 Gm37035 MGI:MGI:5610263 +105244456 Gm40061 MGI:MGI:5622946 +105244457 Gm40062 MGI:MGI:5622947 +105244458 Gm40063 MGI:MGI:5622948 +105244459 Gm40064 MGI:MGI:5622949 +105244460 Gm40065 MGI:MGI:5622950 +105244461 Gm40066 MGI:MGI:5622951 +105244462 Gm37359 MGI:MGI:5610587 +105244463 LOC105244463 - +105244464 Gm40067 MGI:MGI:5622952 +105244465 Gm40068 MGI:MGI:5622953 +105244466 Gm40069 MGI:MGI:5622954 +105244467 LOC105244467 - +105244468 Gm40070 MGI:MGI:5622955 +105244469 Gm40071 MGI:MGI:5622956 +105244470 Gm40072 MGI:MGI:5622957 +105244471 Gm40073 MGI:MGI:5622958 +105244472 Gm40074 MGI:MGI:5622959 +105244473 Gm40075 MGI:MGI:5622960 +105244474 Gm40076 MGI:MGI:5622961 +105244475 Gm40077 MGI:MGI:5622962 +105244476 Gm36981 MGI:MGI:5610209 +105244477 Gm40078 MGI:MGI:5622963 +105244478 Gm40079 MGI:MGI:5622964 +105244479 Gm40080 MGI:MGI:5622965 +105244480 Gm40081 MGI:MGI:5622966 +105244481 Gm40082 MGI:MGI:5622967 +105244482 Gm40083 MGI:MGI:5622968 +105244483 Gm40084 MGI:MGI:5622969 +105244484 Gm40085 MGI:MGI:5622970 +105244485 Gm40086 MGI:MGI:5622971 +105244486 LOC105244486 - +105244487 LOC105244487 - +105244489 Gm40087 MGI:MGI:5622972 +105244490 Gm40088 MGI:MGI:5622973 +105244491 Gm37116 MGI:MGI:5610344 +105244492 Gm40089 MGI:MGI:5622974 +105244493 Gm40090 MGI:MGI:5622975 +105244494 Gm40091 MGI:MGI:5622976 +105244495 Gm40092 MGI:MGI:5622977 +105244496 Gm40093 MGI:MGI:5622978 +105244497 Gm40094 MGI:MGI:5622979 +105244498 Gm40095 MGI:MGI:5622980 +105244499 Gm40096 MGI:MGI:5622981 +105244500 Gm40097 MGI:MGI:5622982 +105244502 Gm26654 MGI:MGI:5477148 +105244503 Gm40098 MGI:MGI:5622983 +105244504 Gm40099 MGI:MGI:5622984 +105244505 Gm40100 MGI:MGI:5622985 +105244506 Gm16253 MGI:MGI:3826531 +105244507 Gm40101 MGI:MGI:5622986 +105244508 Gm40102 MGI:MGI:5622987 +105244509 Gm40103 MGI:MGI:5622988 +105244510 Gm40104 MGI:MGI:5622989 +105244511 Gm40105 MGI:MGI:5622990 +105244512 Gm40106 MGI:MGI:5622991 +105244513 Gm40107 MGI:MGI:5622992 +105244514 Gm40108 MGI:MGI:5622993 +105244515 Gm40109 MGI:MGI:5622994 +105244516 Gm40110 MGI:MGI:5622995 +105244517 Gm40111 MGI:MGI:5622996 +105244518 Gm40112 MGI:MGI:5622997 +105244519 Gm40113 MGI:MGI:5622998 +105244520 Gm40114 MGI:MGI:5622999 +105244521 Gm40115 MGI:MGI:5623000 +105244522 Gm40116 MGI:MGI:5623001 +105244523 Gm40117 MGI:MGI:5623002 +105244524 Gm40118 MGI:MGI:5623003 +105244525 Gm40119 MGI:MGI:5623004 +105244526 Gm40120 MGI:MGI:5623005 +105244527 Gm40121 MGI:MGI:5623006 +105244528 Gm40122 MGI:MGI:5623007 +105244529 Gm40123 MGI:MGI:5623008 +105244530 LOC105244530 - +105244531 Gm40124 MGI:MGI:5623009 +105244532 Gm40125 MGI:MGI:5623010 +105244533 Gm40126 MGI:MGI:5623011 +105244534 Gm40127 MGI:MGI:5623012 +105244535 Gm40128 MGI:MGI:5623013 +105244536 Gm40129 MGI:MGI:5623014 +105244537 Gm40130 MGI:MGI:5623015 +105244538 Gm40131 MGI:MGI:5623016 +105244539 Gm40132 MGI:MGI:5623017 +105244540 Gm40133 MGI:MGI:5623018 +105244541 Gm40134 MGI:MGI:5623019 +105244542 Gm40135 MGI:MGI:5623020 +105244543 Gm40136 MGI:MGI:5623021 +105244544 Gm40137 MGI:MGI:5623022 +105244545 Gm40138 MGI:MGI:5623023 +105244546 Gm40139 MGI:MGI:5623024 +105244547 Gm40140 MGI:MGI:5623025 +105244548 Gm40141 MGI:MGI:5623026 +105244549 Gm40142 MGI:MGI:5623027 +105244550 Gm40143 MGI:MGI:5623028 +105244551 Gm40144 MGI:MGI:5623029 +105244552 Gm40145 MGI:MGI:5623030 +105244553 Gm40146 MGI:MGI:5623031 +105244554 Gm40147 MGI:MGI:5623032 +105244555 Gm40148 MGI:MGI:5623033 +105244556 Gm40149 MGI:MGI:5623034 +105244557 Gm40150 MGI:MGI:5623035 +105244558 Gm40151 MGI:MGI:5623036 +105244559 Gm40152 MGI:MGI:5623037 +105244560 Gm40153 MGI:MGI:5623038 +105244561 Gm40154 MGI:MGI:5623039 +105244562 Gm40155 MGI:MGI:5623040 +105244563 Gm40156 MGI:MGI:5623041 +105244564 Gm40157 MGI:MGI:5623042 +105244565 Gm40158 MGI:MGI:5623043 +105244566 Gm40159 MGI:MGI:5623044 +105244567 Gm40160 MGI:MGI:5623045 +105244568 Gm40161 MGI:MGI:5623046 +105244569 Gm40162 MGI:MGI:5623047 +105244570 Gm40163 MGI:MGI:5623048 +105244571 Gm40164 MGI:MGI:5623049 +105244572 Gm40165 MGI:MGI:5623050 +105244573 Gm40166 MGI:MGI:5623051 +105244574 Gm40167 MGI:MGI:5623052 +105244575 Gm40168 MGI:MGI:5623053 +105244576 Gm40169 MGI:MGI:5623054 +105244577 Gm40170 MGI:MGI:5623055 +105244578 Gm40171 MGI:MGI:5623056 +105244579 Gm40172 MGI:MGI:5623057 +105244580 Gm37041 MGI:MGI:5610269 +105244581 Gm40173 MGI:MGI:5623058 +105244582 Gm40174 MGI:MGI:5623059 +105244583 Gm40175 MGI:MGI:5623060 +105244584 Gm40176 MGI:MGI:5623061 +105244585 Gm40177 MGI:MGI:5623062 +105244587 Gm40178 MGI:MGI:5623063 +105244588 Gm40179 MGI:MGI:5623064 +105244589 Gm40180 MGI:MGI:5623065 +105244590 Gm16231 MGI:MGI:3802089 +105244591 Gm40181 MGI:MGI:5623066 +105244592 Gm40182 MGI:MGI:5623067 +105244593 Gm40183 MGI:MGI:5623068 +105244594 Gm40184 MGI:MGI:5623069 +105244595 Gm40185 MGI:MGI:5623070 +105244596 Gm40186 MGI:MGI:5623071 +105244597 Gm40187 MGI:MGI:5623072 +105244598 Gm40188 MGI:MGI:5623073 +105244599 Gm40189 MGI:MGI:5623074 +105244600 Gm40190 MGI:MGI:5623075 +105244601 Gm40191 MGI:MGI:5623076 +105244602 Gm40192 MGI:MGI:5623077 +105244603 Gm40193 MGI:MGI:5623078 +105244605 Gm40194 MGI:MGI:5623079 +105244606 Gm40195 MGI:MGI:5623080 +105244608 Gm40196 MGI:MGI:5623081 +105244609 Gm40197 MGI:MGI:5623082 +105244610 Gm40198 MGI:MGI:5623083 +105244611 Gm12333 MGI:MGI:3652064 +105244613 Gm40199 MGI:MGI:5623084 +105244615 Gm40200 MGI:MGI:5623085 +105244617 LOC105244617 - +105244618 Gm40201 MGI:MGI:5623086 +105244619 Gm40202 MGI:MGI:5623087 +105244620 Gm40203 MGI:MGI:5623088 +105244621 Gm40204 MGI:MGI:5623089 +105244622 Gm40205 MGI:MGI:5623090 +105244623 Gm12694 MGI:MGI:3651291 +105244624 Gm12708 MGI:MGI:3652178 +105244625 Gm40206 MGI:MGI:5623091 +105244626 Gm40207 MGI:MGI:5623092 +105244627 Gm40208 MGI:MGI:5623093 +105244628 Gm40209 MGI:MGI:5623094 +105244629 Gm40210 MGI:MGI:5623095 +105244630 Gm26520 MGI:MGI:5477014 +105244631 Gm40211 MGI:MGI:5623096 +105244632 Gm40212 MGI:MGI:5623097 +105244633 Gm40213 MGI:MGI:5623098 +105244634 Gm12701 MGI:MGI:3650875 +105244635 Ube2uos MGI:MGI:3651101 +105244636 LOC105244636 - +105244637 Gm40214 MGI:MGI:5623099 +105244638 Gm40215 MGI:MGI:5623100 +105244639 Gm40216 MGI:MGI:5623101 +105244640 Gm40217 MGI:MGI:5623102 +105244641 Gm12724 MGI:MGI:3649755 +105244642 Gm40218 MGI:MGI:5623103 +105244643 Gm40219 MGI:MGI:5623104 +105244644 Lrp8os3 MGI:MGI:3651133|Ensembl:ENSMUSG00000087200 +105244645 Gm40220 MGI:MGI:5623105 +105244646 Gm40221 MGI:MGI:5623106 +105244647 Gm40222 MGI:MGI:5623107 +105244648 LOC105244648 - +105244649 LOC105244649 - +105244650 Gm40223 MGI:MGI:5623108 +105244651 LOC105244651 - +105244652 Gm40224 MGI:MGI:5623109 +105244653 Gm40225 MGI:MGI:5623110 +105244654 Gm40226 MGI:MGI:5623111 +105244655 Gm40227 MGI:MGI:5623112 +105244657 LOC105244657 - +105244658 Gm40228 MGI:MGI:5623113 +105244659 LOC105244659 - +105244660 Gm40229 MGI:MGI:5623114 +105244661 Gm40230 MGI:MGI:5623115 +105244662 Cyp4x1os MGI:MGI:3649427|Ensembl:ENSMUSG00000086896 +105244664 Gm40231 MGI:MGI:5623116 +105244665 Gm12826 MGI:MGI:3650150 +105244666 Gm40232 MGI:MGI:5623117 +105244667 Gm40233 MGI:MGI:5623118 +105244668 Gm40234 MGI:MGI:5623119 +105244669 Gm40235 MGI:MGI:5623120 +105244670 Gm40236 MGI:MGI:5623121 +105244671 Gm40237 MGI:MGI:5623122 +105244672 Gm12865 MGI:MGI:3651214 +105244673 Gm40238 MGI:MGI:5623123 +105244674 Gm12867 MGI:MGI:3651003 +105244675 Gm40239 MGI:MGI:5623124 +105244676 Gm12923 MGI:MGI:3651539 +105244677 LOC105244677 - +105244678 Gm40240 MGI:MGI:5623125 +105244679 Gm40241 MGI:MGI:5623126 +105244680 Gm40242 MGI:MGI:5623127 +105244681 Gm40243 MGI:MGI:5623128 +105244682 Gm40244 MGI:MGI:5623129 +105244683 Gm40245 MGI:MGI:5623130 +105244684 Gm40246 MGI:MGI:5623131 +105244685 Gm40247 MGI:MGI:5623132 +105244686 Gm40248 MGI:MGI:5623133 +105244687 Gm40249 MGI:MGI:5623134 +105244688 Gm40250 MGI:MGI:5623135 +105244689 Gm40251 MGI:MGI:5623136 +105244690 Gm40252 MGI:MGI:5623137 +105244691 Gm40253 MGI:MGI:5623138 +105244692 Gm40254 MGI:MGI:5623139 +105244693 Gm40255 MGI:MGI:5623140 +105244694 Gm40256 MGI:MGI:5623141 +105244695 Gm12958 MGI:MGI:3652007 +105244696 Gm15904 MGI:MGI:3801803|Ensembl:ENSMUSG00000085961 +105244697 Gm40257 MGI:MGI:5623142 +105244698 LOC105244698 - +105244699 Gm40258 MGI:MGI:5623143 +105244700 Gm40259 MGI:MGI:5623144 +105244701 Gm40260 MGI:MGI:5623145 +105244702 Gm40261 MGI:MGI:5623146 +105244703 Gm40262 MGI:MGI:5623147 +105244704 Gm40263 MGI:MGI:5623148 +105244705 Gm40264 MGI:MGI:5623149 +105244706 Gm40265 MGI:MGI:5623150 +105244707 Gm40266 MGI:MGI:5623151 +105244708 LOC105244708 - +105244709 Gm40267 MGI:MGI:5623152 +105244710 Gm40268 MGI:MGI:5623153 +105244711 Gm40269 MGI:MGI:5623154 +105244712 Gm40270 MGI:MGI:5623155 +105244713 Gm40271 MGI:MGI:5623156|Ensembl:ENSMUSG00000113465 +105244714 Gm40272 MGI:MGI:5623157 +105244715 Gm40273 MGI:MGI:5623158 +105244716 Gm40274 MGI:MGI:5623159 +105244717 Gm40275 MGI:MGI:5623160 +105244718 Gm40276 MGI:MGI:5623161 +105244719 Gm40277 MGI:MGI:5623162 +105244720 Gm40278 MGI:MGI:5623163 +105244721 Gm40279 MGI:MGI:5623164 +105244722 Gm40280 MGI:MGI:5623165 +105244723 Gm40281 MGI:MGI:5623166 +105244724 Gm40282 MGI:MGI:5623167 +105244725 Gm40283 MGI:MGI:5623168 +105244726 Gm40284 MGI:MGI:5623169 +105244727 Gm40285 MGI:MGI:5623170 +105244728 Gm40286 MGI:MGI:5623171 +105244729 Gm40287 MGI:MGI:5623172 +105244730 Gm40288 MGI:MGI:5623173 +105244731 Gm40289 MGI:MGI:5623174 +105244732 Gm40290 MGI:MGI:5623175 +105244733 Gm15796 MGI:MGI:3801844 +105244734 Gm40291 MGI:MGI:5623176 +105244735 Gm40292 MGI:MGI:5623177 +105244736 Gm40293 MGI:MGI:5623178 +105244737 Gm40294 MGI:MGI:5623179 +105244738 Gm40295 MGI:MGI:5623180 +105244739 Gm15866 MGI:MGI:3801874 +105244740 Gm40296 MGI:MGI:5623181 +105244741 Gm40297 MGI:MGI:5623182 +105244742 Gm40298 MGI:MGI:5623183 +105244743 Gm40299 MGI:MGI:5623184 +105244744 Gm40300 MGI:MGI:5623185 +105244745 Gm40301 MGI:MGI:5623186 +105244746 Gm40302 MGI:MGI:5623187 +105244747 Gm40303 MGI:MGI:5623188 +105244748 Gm40304 MGI:MGI:5623189 +105244749 Gm40305 MGI:MGI:5623190 +105244751 Gm40306 MGI:MGI:5623191 +105244752 Gm40307 MGI:MGI:5623192 +105244753 Gm40308 MGI:MGI:5623193 +105244754 LOC105244754 - +105244755 LOC105244755 - +105244756 Gm40309 MGI:MGI:5623194 +105244757 Gm40310 MGI:MGI:5623195 +105244758 Gm40311 MGI:MGI:5623196 +105244759 Gm40312 MGI:MGI:5623197 +105244760 Gm40313 MGI:MGI:5623198 +105244761 Gm40314 MGI:MGI:5623199 +105244762 Gm40315 MGI:MGI:5623200 +105244764 Gm40316 MGI:MGI:5623201 +105244765 Gm40317 MGI:MGI:5623202 +105244766 Gm40318 MGI:MGI:5623203 +105244767 Gm40319 MGI:MGI:5623204 +105244768 Gm40320 MGI:MGI:5623205 +105244769 Gm40321 MGI:MGI:5623206 +105244770 Gm40322 MGI:MGI:5623207 +105244771 Gm40323 MGI:MGI:5623208 +105244772 Gm40324 MGI:MGI:5623209 +105244773 Gm40325 MGI:MGI:5623210 +105244774 Gm40326 MGI:MGI:5623211 +105244775 Gm40327 MGI:MGI:5623212 +105244776 Gm40328 MGI:MGI:5623213 +105244777 Gm40329 MGI:MGI:5623214 +105244778 Gm40330 MGI:MGI:5623215 +105244779 Gm40331 MGI:MGI:5623216 +105244780 Gm40332 MGI:MGI:5623217 +105244781 Gm40333 MGI:MGI:5623218 +105244784 Gm40334 MGI:MGI:5623219 +105244785 Gm40335 MGI:MGI:5623220 +105244786 Gm40336 MGI:MGI:5623221 +105244787 Gm40337 MGI:MGI:5623222 +105244788 Gm40338 MGI:MGI:5623223 +105244789 Gm40339 MGI:MGI:5623224 +105244790 Gm40340 MGI:MGI:5623225 +105244791 Gm40341 MGI:MGI:5623226 +105244793 LOC105244793 - +105244794 Gm40342 MGI:MGI:5623227 +105244795 Gm40343 MGI:MGI:5623228 +105244796 Gm40344 MGI:MGI:5623229 +105244797 Gm40345 MGI:MGI:5623230 +105244798 LOC105244798 - +105244799 Gm40346 MGI:MGI:5623231 +105244800 Gm40347 MGI:MGI:5623232 +105244801 Gm16599 MGI:MGI:4439523 +105244802 Gm40348 MGI:MGI:5623233 +105244803 LOC105244803 - +105244804 Gm40349 MGI:MGI:5623234 +105244805 Gm40350 MGI:MGI:5623235 +105244806 Gm40351 MGI:MGI:5623236 +105244807 Gm40352 MGI:MGI:5623237 +105244808 Gm40353 MGI:MGI:5623238 +105244809 Gm40354 MGI:MGI:5623239 +105244810 Gm40355 MGI:MGI:5623240 +105244811 Gm40356 MGI:MGI:5623241 +105244812 LOC105244812 - +105244813 Gm40357 MGI:MGI:5623242 +105244814 Gm40358 MGI:MGI:5623243 +105244821 Gm15691 MGI:MGI:3783132|Ensembl:ENSMUSG00000085472 +105244822 Gm40359 MGI:MGI:5623244 +105244823 Gm40360 MGI:MGI:5623245 +105244824 Gm40361 MGI:MGI:5623246 +105244825 Gm40362 MGI:MGI:5623247 +105244826 Gm40363 MGI:MGI:5623248 +105244828 Gm40364 MGI:MGI:5623249 +105244829 Gm40365 MGI:MGI:5623250 +105244830 Gm40366 MGI:MGI:5623251 +105244831 Gm40367 MGI:MGI:5623252 +105244832 Gm40368 MGI:MGI:5623253 +105244833 Gm40369 MGI:MGI:5623254 +105244834 Gm40370 MGI:MGI:5623255 +105244835 Gm40371 MGI:MGI:5623256 +105244836 Gm40372 MGI:MGI:5623257 +105244837 Gm40373 MGI:MGI:5623258 +105244838 Gm40374 MGI:MGI:5623259 +105244840 Gm40375 MGI:MGI:5623260 +105244841 Gm40376 MGI:MGI:5623261 +105244842 LOC105244842 - +105244843 Gm40377 MGI:MGI:5623262 +105244844 Gm40378 MGI:MGI:5623263 +105244845 Gm40379 MGI:MGI:5623264 +105244846 Gm40380 MGI:MGI:5623265 +105244847 Gm40381 MGI:MGI:5623266 +105244848 Gm40382 MGI:MGI:5623267 +105244849 Gm40383 MGI:MGI:5623268 +105244850 Gm40384 MGI:MGI:5623269 +105244851 Gm40385 MGI:MGI:5623270 +105244852 Gm40386 MGI:MGI:5623271 +105244853 Gm40387 MGI:MGI:5623272 +105244854 Gm40388 MGI:MGI:5623273 +105244855 Gm40389 MGI:MGI:5623274 +105244857 Gm40390 MGI:MGI:5623275 +105244858 Gm40391 MGI:MGI:5623276 +105244859 Gm40392 MGI:MGI:5623277|Ensembl:ENSMUSG00000113832 +105244860 Gm40393 MGI:MGI:5623278 +105244861 Gm40394 MGI:MGI:5623279 +105244862 Gm29007 MGI:MGI:5579713 +105244863 Gm40395 MGI:MGI:5623280 +105244865 Gm40396 MGI:MGI:5623281 +105244866 Gm40397 MGI:MGI:5623282 +105244867 Gm40398 MGI:MGI:5623283 +105244868 Gm40399 MGI:MGI:5623284 +105244869 Gm40400 MGI:MGI:5623285 +105244870 Gm40401 MGI:MGI:5623286 +105244871 Gm40402 MGI:MGI:5623287 +105244872 Gm40403 MGI:MGI:5623288 +105244873 Gm40404 MGI:MGI:5623289 +105244874 Gm40405 MGI:MGI:5623290 +105244875 Gm40406 MGI:MGI:5623291 +105244876 Gm17089 MGI:MGI:4937916 +105244877 Gm40407 MGI:MGI:5623292 +105244878 Gm40408 MGI:MGI:5623293 +105244879 Gm14330 MGI:MGI:3650200 +105244881 Gm40409 MGI:MGI:5623294 +105244882 Gm40410 MGI:MGI:5623295 +105244883 Gm40411 MGI:MGI:5623296 +105244884 Gm40412 MGI:MGI:5623297 +105244885 Gm40413 MGI:MGI:5623298 +105244886 Gm40414 MGI:MGI:5623299 +105244887 Gm40415 MGI:MGI:5623300 +105244888 Gm40416 MGI:MGI:5623301 +105244889 Gm40417 MGI:MGI:5623302 +105244890 Gm40418 MGI:MGI:5623303|Ensembl:ENSMUSG00000112353 +105244891 Gm40419 MGI:MGI:5623304 +105244892 Gm40420 MGI:MGI:5623305 +105244893 Gm40421 MGI:MGI:5623306 +105244894 Gm40422 MGI:MGI:5623307 +105244895 Gm40423 MGI:MGI:5623308 +105244898 Gm40424 MGI:MGI:5623309 +105244899 Gm40425 MGI:MGI:5623310 +105244902 Gm40426 MGI:MGI:5623311 +105244903 Gm40427 MGI:MGI:5623312 +105244904 Gm40428 MGI:MGI:5623313 +105244905 Gm40429 MGI:MGI:5623314 +105244906 Gm40430 MGI:MGI:5623315 +105244907 Gm40431 MGI:MGI:5623316 +105244908 LOC105244908 - +105244909 Gm40432 MGI:MGI:5623317 +105244910 Gm40433 MGI:MGI:5623318 +105244911 Gm40434 MGI:MGI:5623319 +105244912 Gm40435 MGI:MGI:5623320 +105244913 Gm40436 MGI:MGI:5623321 +105244914 LOC105244914 - +105244915 Gm40437 MGI:MGI:5623322 +105244916 Gm40438 MGI:MGI:5623323 +105244917 Gm40439 MGI:MGI:5623324 +105244918 Gm40440 MGI:MGI:5623325 +105244919 Gm40441 MGI:MGI:5623326 +105244920 Gm40442 MGI:MGI:5623327 +105244921 Gm40443 MGI:MGI:5623328 +105244922 Gm40444 MGI:MGI:5623329 +105244923 Gm40445 MGI:MGI:5623330 +105244924 Gm40446 MGI:MGI:5623331 +105244925 Gm40447 MGI:MGI:5623332 +105244926 Gm40448 MGI:MGI:5623333 +105244927 Gm40449 MGI:MGI:5623334 +105244928 Gm40450 MGI:MGI:5623335 +105244929 Gm40451 MGI:MGI:5623336 +105244930 Gm40452 MGI:MGI:5623337 +105244931 Gm40453 MGI:MGI:5623338 +105244932 Gm40454 MGI:MGI:5623339 +105244933 Gm40455 MGI:MGI:5623340 +105244934 Gm40456 MGI:MGI:5623341 +105244935 Gm40457 MGI:MGI:5623342 +105244936 Gm40458 MGI:MGI:5623343 +105244937 Gm40459 MGI:MGI:5623344 +105244938 Gm40460 MGI:MGI:5623345|Ensembl:ENSMUSG00000110324|Vega:OTTMUSG00000060166 +105244939 Gm40461 MGI:MGI:5623346 +105244940 Gm40462 MGI:MGI:5623347 +105244941 Gm40463 MGI:MGI:5623348 +105244942 Gm40464 MGI:MGI:5623349 +105244943 Gm40465 MGI:MGI:5623350 +105244944 Gm40466 MGI:MGI:5623351 +105244945 Gm40467 MGI:MGI:5623352 +105244946 Gm40468 MGI:MGI:5623353 +105244947 Gm40469 MGI:MGI:5623354 +105244948 Gm40470 MGI:MGI:5623355 +105244949 Gm40471 MGI:MGI:5623356 +105244950 LOC105244950 - +105244951 Gm40472 MGI:MGI:5623357 +105244953 LOC105244953 - +105244954 Gm40473 MGI:MGI:5623358 +105244955 LOC105244955 - +105244956 Gm40474 MGI:MGI:5623359 +105244957 Gm40475 MGI:MGI:5623360 +105244958 Gm40476 MGI:MGI:5623361 +105244959 Gm40477 MGI:MGI:5623362 +105244960 Gm40478 MGI:MGI:5623363 +105244961 Gm40479 MGI:MGI:5623364 +105244962 Gm40480 MGI:MGI:5623365 +105244963 Gm40481 MGI:MGI:5623366 +105244964 Gm40482 MGI:MGI:5623367 +105244965 Gm40483 MGI:MGI:5623368 +105244966 Gm40484 MGI:MGI:5623369 +105244967 Gm40485 MGI:MGI:5623370 +105244968 Gm40486 MGI:MGI:5623371 +105244969 Gm40487 MGI:MGI:5623372 +105244970 Gm40488 MGI:MGI:5623373 +105244971 Gm40489 MGI:MGI:5623374 +105244972 Gm40490 MGI:MGI:5623375 +105244973 Gm40491 MGI:MGI:5623376 +105244974 Gm40492 MGI:MGI:5623377 +105244975 Gm40493 MGI:MGI:5623378 +105244976 Gm40494 MGI:MGI:5623379 +105244977 Gm40495 MGI:MGI:5623380 +105244978 Gm40496 MGI:MGI:5623381 +105244979 Gm40497 MGI:MGI:5623382 +105244980 Gm40498 MGI:MGI:5623383 +105244981 Gm40499 MGI:MGI:5623384 +105244982 Gm26584 MGI:MGI:5477078 +105244983 Gm40500 MGI:MGI:5623385 +105244984 Gm40501 MGI:MGI:5623386 +105244985 Gm40502 MGI:MGI:5623387 +105244986 Gm40503 MGI:MGI:5623388 +105244987 Gm40504 MGI:MGI:5623389 +105244988 Gm40505 MGI:MGI:5623390 +105244989 Gm40506 MGI:MGI:5623391 +105244990 Gm40507 MGI:MGI:5623392 +105244991 Gm40508 MGI:MGI:5623393 +105244992 Gm40509 MGI:MGI:5623394 +105244993 LOC105244993 - +105244994 LOC105244994 - +105244995 Gm40510 MGI:MGI:5623395 +105244996 Gm40511 MGI:MGI:5623396 +105244997 Gm40512 MGI:MGI:5623397 +105244998 Gm40513 MGI:MGI:5623398 +105244999 Gm40514 MGI:MGI:5623399 +105245000 Gm40515 MGI:MGI:5623400 +105245001 Gm40516 MGI:MGI:5623401 +105245002 Gm40517 MGI:MGI:5623402 +105245003 Gm40518 MGI:MGI:5623403|Ensembl:ENSMUSG00000110924 +105245004 Gm40519 MGI:MGI:5623404 +105245005 Gm40520 MGI:MGI:5623405 +105245007 Gm40521 MGI:MGI:5623406 +105245008 Gm40522 MGI:MGI:5623407 +105245009 Gm40523 MGI:MGI:5623408 +105245010 Gm40524 MGI:MGI:5623409 +105245011 Gm40525 MGI:MGI:5623410 +105245012 Gm40526 MGI:MGI:5623411 +105245013 Gm40527 MGI:MGI:5623412 +105245014 Gm40528 MGI:MGI:5623413 +105245015 Gm40529 MGI:MGI:5623414 +105245016 Gm40530 MGI:MGI:5623415 +105245017 Gm40531 MGI:MGI:5623416 +105245018 Gm40532 MGI:MGI:5623417 +105245019 Gm40533 MGI:MGI:5623418 +105245020 Gm40534 MGI:MGI:5623419 +105245021 Gm40535 MGI:MGI:5623420 +105245022 Gm40536 MGI:MGI:5623421 +105245023 Gm40537 MGI:MGI:5623422 +105245024 Gm40538 MGI:MGI:5623423|Ensembl:ENSMUSG00000113001 +105245025 Gm26567 MGI:MGI:5477061 +105245027 Gm26611 MGI:MGI:5477105|Ensembl:ENSMUSG00000097677 +105245028 Gm40539 MGI:MGI:5623424 +105245029 Gm40540 MGI:MGI:5623425 +105245030 Gm40541 MGI:MGI:5623426 +105245031 Gm40542 MGI:MGI:5623427 +105245032 Gm40543 MGI:MGI:5623428 +105245033 Gm40544 MGI:MGI:5623429 +105245034 Gm40545 MGI:MGI:5623430 +105245035 Gm40546 MGI:MGI:5623431 +105245036 Gm40547 MGI:MGI:5623432 +105245037 Gm40548 MGI:MGI:5623433 +105245038 Gm40549 MGI:MGI:5623434 +105245039 Gm40550 MGI:MGI:5623435 +105245040 Gm40551 MGI:MGI:5623436 +105245041 Gm40552 MGI:MGI:5623437 +105245042 Gm40553 MGI:MGI:5623438 +105245043 LOC105245043 - +105245044 Gm40554 MGI:MGI:5623439 +105245046 Gm40555 MGI:MGI:5623440 +105245047 Gm40556 MGI:MGI:5623441 +105245048 Gm40557 MGI:MGI:5623442|Ensembl:ENSMUSG00000113362 +105245049 Gm40558 MGI:MGI:5623443 +105245050 Gm40559 MGI:MGI:5623444 +105245051 LOC105245051 - +105245052 Gm40560 MGI:MGI:5623445 +105245053 Gm40561 MGI:MGI:5623446 +105245054 Gm40562 MGI:MGI:5623447 +105245055 Gm40563 MGI:MGI:5623448 +105245058 LOC105245058 - +105245059 Gm40564 MGI:MGI:5623449 +105245061 Gm40565 MGI:MGI:5623450 +105245062 Gm40566 MGI:MGI:5623451 +105245063 Gm40567 MGI:MGI:5623452 +105245065 Gm40568 MGI:MGI:5623453 +105245066 Gm40569 MGI:MGI:5623454 +105245067 Gm16087 MGI:MGI:3801921 +105245068 Gm40570 MGI:MGI:5623455 +105245069 Gm40571 MGI:MGI:5623456 +105245070 Gm40572 MGI:MGI:5623457 +105245071 Gm40573 MGI:MGI:5623458 +105245072 Gm40574 MGI:MGI:5623459 +105245073 Gm40575 MGI:MGI:5623460 +105245074 Gm40576 MGI:MGI:5623461 +105245075 Gm40577 MGI:MGI:5623462 +105245076 Gm40578 MGI:MGI:5623463 +105245077 Gm40579 MGI:MGI:5623464 +105245078 Gm40580 MGI:MGI:5623465 +105245081 Gm40581 MGI:MGI:5623466 +105245082 Gm40582 MGI:MGI:5623467 +105245083 Gm40583 MGI:MGI:5623468 +105245085 Gm40584 MGI:MGI:5623469 +105245086 Gm40585 MGI:MGI:5623470 +105245087 Gm40586 MGI:MGI:5623471 +105245088 Gm40587 MGI:MGI:5623472 +105245090 Gm40588 MGI:MGI:5623473 +105245091 Gm40589 MGI:MGI:5623474 +105245092 Gm40590 MGI:MGI:5623475 +105245093 Gm40591 MGI:MGI:5623476 +105245094 Gm40592 MGI:MGI:5623477 +105245095 Gm40593 MGI:MGI:5623478 +105245096 Gm40594 MGI:MGI:5623479 +105245097 Gm40595 MGI:MGI:5623480 +105245098 Gm40596 MGI:MGI:5623481 +105245099 Gm40597 MGI:MGI:5623482 +105245101 Gm40598 MGI:MGI:5623483 +105245102 LOC105245102 - +105245103 Gm20470 MGI:MGI:5141935 +105245104 Gm40599 MGI:MGI:5623484 +105245105 LOC105245105 - +105245106 Gm40600 MGI:MGI:5623485 +105245107 Gm40601 MGI:MGI:5623486 +105245108 Gm40602 MGI:MGI:5623487 +105245109 Gm40603 MGI:MGI:5623488 +105245110 Gm40604 MGI:MGI:5623489 +105245111 Gm40605 MGI:MGI:5623490 +105245112 Gm40606 MGI:MGI:5623491 +105245113 Gm40607 MGI:MGI:5623492 +105245114 Gm40608 MGI:MGI:5623493 +105245115 Gm40609 MGI:MGI:5623494 +105245116 Gm40610 MGI:MGI:5623495 +105245117 Gm40611 MGI:MGI:5623496 +105245118 Gm40612 MGI:MGI:5623497 +105245119 Gm40613 MGI:MGI:5623498 +105245120 Gm40614 MGI:MGI:5623499 +105245121 Gm40615 MGI:MGI:5623500 +105245122 Gm40616 MGI:MGI:5623501 +105245123 Gm40617 MGI:MGI:5623502 +105245124 Gm40618 MGI:MGI:5623503 +105245125 Gm40619 MGI:MGI:5623504 +105245126 Gm40620 MGI:MGI:5623505 +105245127 Gm40621 MGI:MGI:5623506 +105245128 Gm40622 MGI:MGI:5623507 +105245129 Gm40623 MGI:MGI:5623508 +105245130 Gm40624 MGI:MGI:5623509 +105245131 Gm40625 MGI:MGI:5623510 +105245133 Gm40626 MGI:MGI:5623511 +105245134 Gm40627 MGI:MGI:5623512 +105245135 Gm40628 MGI:MGI:5623513 +105245136 Gm40629 MGI:MGI:5623514 +105245137 Gm40630 MGI:MGI:5623515 +105245138 Gm40631 MGI:MGI:5623516 +105245139 Gm40632 MGI:MGI:5623517 +105245140 Gm40633 MGI:MGI:5623518 +105245141 Gm40634 MGI:MGI:5623519 +105245142 Gm40635 MGI:MGI:5623520 +105245143 Gm40636 MGI:MGI:5623521 +105245144 Gm40637 MGI:MGI:5623522 +105245145 Gm40638 MGI:MGI:5623523|Ensembl:ENSMUSG00000110898 +105245146 Gm40639 MGI:MGI:5623524 +105245147 Gm40640 MGI:MGI:5623525 +105245148 Gm40641 MGI:MGI:5623526 +105245149 Gm40642 MGI:MGI:5623527 +105245150 Gm40643 MGI:MGI:5623528 +105245151 Gm40644 MGI:MGI:5623529 +105245152 LOC105245152 - +105245153 Gm40645 MGI:MGI:5623530 +105245154 Gm40646 MGI:MGI:5623531 +105245155 Gm40647 MGI:MGI:5623532 +105245156 Gm40648 MGI:MGI:5623533 +105245157 Gm40649 MGI:MGI:5623534 +105245158 Gm40650 MGI:MGI:5623535 +105245159 Gm40651 MGI:MGI:5623536 +105245160 Gm40652 MGI:MGI:5623537 +105245162 Gm40653 MGI:MGI:5623538 +105245163 Gm40654 MGI:MGI:5623539 +105245164 Gm40655 MGI:MGI:5623540 +105245165 Gm40656 MGI:MGI:5623541 +105245166 Gm40657 MGI:MGI:5623542 +105245168 Gm40658 MGI:MGI:5623543 +105245169 Gm40659 MGI:MGI:5623544 +105245170 Gm40660 MGI:MGI:5623545 +105245171 Gm40661 MGI:MGI:5623546 +105245172 Gm40662 MGI:MGI:5623547 +105245173 Gm40663 MGI:MGI:5623548 +105245174 Gm40664 MGI:MGI:5623549 +105245175 Gm40665 MGI:MGI:5623550 +105245176 Gm40666 MGI:MGI:5623551 +105245177 Gm40667 MGI:MGI:5623552 +105245179 Gm20513 MGI:MGI:5141978 +105245180 Gm40668 MGI:MGI:5623553 +105245181 Gm40669 MGI:MGI:5623554 +105245182 Gm40670 MGI:MGI:5623555 +105245183 Gm40671 MGI:MGI:5623556 +105245184 Gm40672 MGI:MGI:5623557 +105245185 Gm40673 MGI:MGI:5623558 +105245186 Gm28447 MGI:MGI:5579153 +105245187 Gm40674 MGI:MGI:5623559 +105245188 Gm40675 MGI:MGI:5623560 +105245189 Gm40676 MGI:MGI:5623561 +105245190 Gm40677 MGI:MGI:5623562 +105245191 Gm40678 MGI:MGI:5623563 +105245192 Gm40679 MGI:MGI:5623564 +105245193 LOC105245193 - +105245194 Gm40680 MGI:MGI:5623565 +105245195 Gm40681 MGI:MGI:5623566 +105245196 Gm40682 MGI:MGI:5623567 +105245197 Gm40683 MGI:MGI:5623568 +105245198 Gm40684 MGI:MGI:5623569 +105245199 Gm40685 MGI:MGI:5623570 +105245200 Gm40686 MGI:MGI:5623571 +105245201 Gm40687 MGI:MGI:5623572 +105245202 Gm40688 MGI:MGI:5623573 +105245203 Gm40689 MGI:MGI:5623574 +105245205 Gm40690 MGI:MGI:5623575 +105245206 Gm40691 MGI:MGI:5623576 +105245207 Gm40692 MGI:MGI:5623577 +105245208 Gm40693 MGI:MGI:5623578 +105245209 Gm40694 MGI:MGI:5623579 +105245210 Gm40695 MGI:MGI:5623580 +105245211 Gm40696 MGI:MGI:5623581 +105245212 LOC105245212 - +105245213 Gm40697 MGI:MGI:5623582 +105245214 Gm40698 MGI:MGI:5623583 +105245215 Gm40699 MGI:MGI:5623584 +105245216 Gm40700 MGI:MGI:5623585 +105245217 Gm40701 MGI:MGI:5623586 +105245218 Gm40702 MGI:MGI:5623587 +105245219 Gm40703 MGI:MGI:5623588 +105245220 Gm40704 MGI:MGI:5623589 +105245221 Gm40705 MGI:MGI:5623590 +105245222 Gm40706 MGI:MGI:5623591 +105245223 Gm40707 MGI:MGI:5623592 +105245224 Gm40708 MGI:MGI:5623593 +105245225 Gm40709 MGI:MGI:5623594 +105245226 Gm40710 MGI:MGI:5623595 +105245227 Gm40711 MGI:MGI:5623596 +105245228 Gm40712 MGI:MGI:5623597 +105245229 Gm40713 MGI:MGI:5623598 +105245230 Gm40714 MGI:MGI:5623599 +105245231 Gm40715 MGI:MGI:5623600 +105245232 Gm40716 MGI:MGI:5623601 +105245233 Gm40717 MGI:MGI:5623602 +105245234 LOC105245234 - +105245235 Gm40718 MGI:MGI:5623603 +105245236 LOC105245236 - +105245237 LOC105245237 - +105245238 Gm40719 MGI:MGI:5623604 +105245239 Gm40720 MGI:MGI:5623605 +105245240 LOC105245240 - +105245241 Gm15608 MGI:MGI:3801804 +105245242 Gm40721 MGI:MGI:5623606 +105245243 Gm40722 MGI:MGI:5623607 +105245244 Gm40723 MGI:MGI:5623608 +105245245 Gm40724 MGI:MGI:5623609 +105245246 Gm40725 MGI:MGI:5623610 +105245247 Gm40726 MGI:MGI:5623611 +105245248 Gm40727 MGI:MGI:5623612 +105245249 Gm40728 MGI:MGI:5623613 +105245250 Gm40729 MGI:MGI:5623614 +105245251 Gm40730 MGI:MGI:5623615 +105245252 Gm40731 MGI:MGI:5623616 +105245253 Gm40732 MGI:MGI:5623617 +105245254 Gm16271 MGI:MGI:3826610 +105245255 Gm40733 MGI:MGI:5623618 +105245256 Gm40734 MGI:MGI:5623619 +105245257 Gm40735 MGI:MGI:5623620 +105245258 Gm40736 MGI:MGI:5623621 +105245259 Gm40737 MGI:MGI:5623622 +105245260 Gm40738 MGI:MGI:5623623 +105245261 Gm40739 MGI:MGI:5623624 +105245262 Gm40740 MGI:MGI:5623625 +105245263 Gm40741 MGI:MGI:5623626 +105245264 Gm40742 MGI:MGI:5623627 +105245265 Gm40743 MGI:MGI:5623628 +105245266 Gm40744 MGI:MGI:5623629 +105245267 Gm40745 MGI:MGI:5623630 +105245268 Gm40746 MGI:MGI:5623631 +105245269 Gm40747 MGI:MGI:5623632 +105245270 Gm40748 MGI:MGI:5623633 +105245271 Gm40749 MGI:MGI:5623634 +105245272 Gm20522 MGI:MGI:5141987|Ensembl:ENSMUSG00000092241 +105245273 Gm40750 MGI:MGI:5623635 +105245274 Gm40751 MGI:MGI:5623636 +105245275 Gm40752 MGI:MGI:5623637 +105245276 Gm40753 MGI:MGI:5623638 +105245277 Gm40754 MGI:MGI:5623639 +105245278 Gm40755 MGI:MGI:5623640 +105245279 LOC105245279 - +105245280 Gm40756 MGI:MGI:5623641 +105245281 Gm40757 MGI:MGI:5623642 +105245282 Gm40758 MGI:MGI:5623643 +105245283 Gm40759 MGI:MGI:5623644 +105245284 Gm40760 MGI:MGI:5623645 +105245285 Gm40761 MGI:MGI:5623646 +105245286 Gm40762 MGI:MGI:5623647 +105245287 Gm40763 MGI:MGI:5623648 +105245288 Gm40764 MGI:MGI:5623649 +105245289 Gm40765 MGI:MGI:5623650 +105245290 Gm40766 MGI:MGI:5623651 +105245291 Gm40767 MGI:MGI:5623652 +105245292 Gm40768 MGI:MGI:5623653 +105245293 Gm40769 MGI:MGI:5623654 +105245294 Gm40770 MGI:MGI:5623655 +105245296 Gm40771 MGI:MGI:5623656 +105245297 Gm40772 MGI:MGI:5623657 +105245298 Gm40773 MGI:MGI:5623658 +105245299 Gm40774 MGI:MGI:5623659 +105245300 Gm40775 MGI:MGI:5623660 +105245301 Gm40776 MGI:MGI:5623661 +105245302 Gm40777 MGI:MGI:5623662 +105245303 Gm40778 MGI:MGI:5623663 +105245304 Gm40779 MGI:MGI:5623664 +105245305 Gm40780 MGI:MGI:5623665 +105245306 Gm40781 MGI:MGI:5623666 +105245307 Gm40782 MGI:MGI:5623667 +105245308 Gm40783 MGI:MGI:5623668 +105245309 Gm40784 MGI:MGI:5623669 +105245310 Gm40785 MGI:MGI:5623670 +105245311 Gm40786 MGI:MGI:5623671 +105245312 Gm40787 MGI:MGI:5623672 +105245313 Gm40788 MGI:MGI:5623673 +105245314 Gm40789 MGI:MGI:5623674 +105245315 Gm40790 MGI:MGI:5623675 +105245316 Gm40791 MGI:MGI:5623676 +105245317 Gm40792 MGI:MGI:5623677 +105245318 Gm40793 MGI:MGI:5623678 +105245319 Gm40794 MGI:MGI:5623679 +105245320 Gm40795 MGI:MGI:5623680 +105245321 Gm40796 MGI:MGI:5623681 +105245322 Gm40797 MGI:MGI:5623682 +105245323 Gm40798 MGI:MGI:5623683 +105245324 Gm40799 MGI:MGI:5623684 +105245325 Gm40800 MGI:MGI:5623685 +105245326 Gm40801 MGI:MGI:5623686 +105245327 Gm40802 MGI:MGI:5623687 +105245328 LOC105245328 - +105245329 Gm40803 MGI:MGI:5623688 +105245330 Gm40804 MGI:MGI:5623689 +105245331 Gm40805 MGI:MGI:5623690 +105245332 Gm40806 MGI:MGI:5623691 +105245333 Gm40807 MGI:MGI:5623692 +105245334 Gm40808 MGI:MGI:5623693 +105245335 Gm40809 MGI:MGI:5623694 +105245336 Gm26923 MGI:MGI:5504038 +105245337 Gm40810 MGI:MGI:5623695 +105245338 Gm40811 MGI:MGI:5623696 +105245340 Gm40812 MGI:MGI:5623697 +105245341 Gm40813 MGI:MGI:5623698 +105245342 Gm40814 MGI:MGI:5623699 +105245343 Gm40815 MGI:MGI:5623700 +105245344 Gm40816 MGI:MGI:5623701 +105245345 Gm40817 MGI:MGI:5623702 +105245346 Gm40818 MGI:MGI:5623703 +105245347 Gm40819 MGI:MGI:5623704 +105245348 Gm40820 MGI:MGI:5623705 +105245349 Gm40821 MGI:MGI:5623706 +105245350 Gm40822 MGI:MGI:5623707 +105245351 Gm40823 MGI:MGI:5623708 +105245353 Gm40824 MGI:MGI:5623709 +105245354 Gm40825 MGI:MGI:5623710 +105245356 Gm40826 MGI:MGI:5623711 +105245357 Gm40827 MGI:MGI:5623712 +105245359 LOC105245359 - +105245360 Gm40828 MGI:MGI:5623713 +105245361 Gm40829 MGI:MGI:5623714 +105245362 Gm40830 MGI:MGI:5623715 +105245363 Gm40831 MGI:MGI:5623716 +105245364 Gm40832 MGI:MGI:5623717 +105245365 LOC105245365 - +105245366 Gm40833 MGI:MGI:5623718 +105245367 Gm11337 MGI:MGI:3651858 +105245368 Gm40834 MGI:MGI:5623719 +105245369 Gm40835 MGI:MGI:5623720 +105245370 Gm40836 MGI:MGI:5623721 +105245371 Gm40837 MGI:MGI:5623722 +105245372 Gm40838 MGI:MGI:5623723 +105245373 Gm40839 MGI:MGI:5623724 +105245374 Gm40840 MGI:MGI:5623725 +105245375 Gm40841 MGI:MGI:5623726 +105245376 Gm40842 MGI:MGI:5623727 +105245377 Gm40843 MGI:MGI:5623728 +105245378 Gm40844 MGI:MGI:5623729 +105245379 Gm40845 MGI:MGI:5623730 +105245380 Gm40846 MGI:MGI:5623731 +105245381 Gm40847 MGI:MGI:5623732 +105245382 LOC105245382 - +105245383 Gm40848 MGI:MGI:5623733 +105245384 Gm40849 MGI:MGI:5623734 +105245386 Gm40850 MGI:MGI:5623735 +105245387 Gm40851 MGI:MGI:5623736 +105245388 Gm40852 MGI:MGI:5623737 +105245389 Gm40853 MGI:MGI:5623738 +105245390 Gm40854 MGI:MGI:5623739 +105245391 Gm40855 MGI:MGI:5623740 +105245392 Gm40856 MGI:MGI:5623741 +105245393 Gm40857 MGI:MGI:5623742 +105245394 Gm40858 MGI:MGI:5623743 +105245396 LOC105245396 - +105245397 Gm40859 MGI:MGI:5623744 +105245398 Gm40860 MGI:MGI:5623745 +105245399 Gm40861 MGI:MGI:5623746 +105245400 Gm40862 MGI:MGI:5623747 +105245401 Gm40863 MGI:MGI:5623748 +105245402 Gm40864 MGI:MGI:5623749 +105245403 Gm40865 MGI:MGI:5623750 +105245404 Gm40866 MGI:MGI:5623751 +105245405 Gm40867 MGI:MGI:5623752 +105245406 LOC105245406 - +105245407 Gm40868 MGI:MGI:5623753 +105245408 Gm40869 MGI:MGI:5623754 +105245409 Gm40870 MGI:MGI:5623755 +105245410 Gm40871 MGI:MGI:5623756 +105245411 LOC105245411 - +105245412 Gm40872 MGI:MGI:5623757 +105245413 Gm11377 MGI:MGI:3650186 +105245414 Gm40873 MGI:MGI:5623758 +105245415 LOC105245415 - +105245416 Gm40874 MGI:MGI:5623759 +105245417 Gm40875 MGI:MGI:5623760 +105245418 Gm40876 MGI:MGI:5623761 +105245419 Gm40877 MGI:MGI:5623762 +105245420 Gm40878 MGI:MGI:5623763 +105245421 Gm40879 MGI:MGI:5623764 +105245422 LOC105245422 - +105245423 Gm40880 MGI:MGI:5623765 +105245424 Gm40881 MGI:MGI:5623766 +105245426 Gm40882 MGI:MGI:5623767 +105245427 Gm40883 MGI:MGI:5623768 +105245428 Gm40884 MGI:MGI:5623769 +105245429 Gm40885 MGI:MGI:5623770 +105245430 Gm40886 MGI:MGI:5623771 +105245431 Gm40887 MGI:MGI:5623772 +105245432 Gm40888 MGI:MGI:5623773 +105245433 Gm40889 MGI:MGI:5623774 +105245434 Gm40890 MGI:MGI:5623775 +105245435 Gm40891 MGI:MGI:5623776 +105245436 Gm40892 MGI:MGI:5623777 +105245437 Gm40893 MGI:MGI:5623778|Ensembl:ENSMUSG00000113613 +105245438 Gm40894 MGI:MGI:5623779 +105245439 LOC105245439 - +105245440 LOC105245440 Ensembl:ENSMUSG00000113136 +105245441 Gm40895 MGI:MGI:5623780 +105245442 Gm40896 MGI:MGI:5623781 +105245443 Gm40897 MGI:MGI:5623782 +105245444 Gm40898 MGI:MGI:5623783 +105245445 Gm40899 MGI:MGI:5623784 +105245446 Gm40900 MGI:MGI:5623785 +105245448 Gm40901 MGI:MGI:5623786 +105245449 Gm40902 MGI:MGI:5623787 +105245451 Gm40903 MGI:MGI:5623788 +105245452 Gm40904 MGI:MGI:5623789 +105245453 LOC105245453 - +105245454 Gm40905 MGI:MGI:5623790 +105245455 Gm40906 MGI:MGI:5623791 +105245457 Gm40907 MGI:MGI:5623792 +105245458 Gm40908 MGI:MGI:5623793 +105245459 Gm40909 MGI:MGI:5623794|Ensembl:ENSMUSG00000113998 +105245460 LOC105245460 - +105245461 Gm40910 MGI:MGI:5623795 +105245462 Gm40911 MGI:MGI:5623796 +105245463 Gm40912 MGI:MGI:5623797 +105245464 Gm40913 MGI:MGI:5623798 +105245465 Gm40914 MGI:MGI:5623799 +105245466 Gm40915 MGI:MGI:5623800 +105245467 Gm40916 MGI:MGI:5623801 +105245468 Gm40917 MGI:MGI:5623802 +105245469 Gm40918 MGI:MGI:5623803 +105245470 Gm40919 MGI:MGI:5623804 +105245471 Gm40920 MGI:MGI:5623805 +105245472 Gm40921 MGI:MGI:5623806 +105245473 Gm40922 MGI:MGI:5623807 +105245474 Gm40923 MGI:MGI:5623808 +105245475 Gm40924 MGI:MGI:5623809 +105245476 Gm40925 MGI:MGI:5623810 +105245477 Gm40926 MGI:MGI:5623811 +105245478 Gm15813 MGI:MGI:3801815 +105245479 Gm40927 MGI:MGI:5623812 +105245480 Gm40928 MGI:MGI:5623813 +105245481 Gm40929 MGI:MGI:5623814 +105245482 Gm40930 MGI:MGI:5623815 +105245483 Gm40931 MGI:MGI:5623816 +105245484 Gm40932 MGI:MGI:5623817 +105245485 Gm40933 MGI:MGI:5623818 +105245486 Gm40934 MGI:MGI:5623819 +105245487 Gm40935 MGI:MGI:5623820 +105245488 Gm40936 MGI:MGI:5623821 +105245489 Gm40937 MGI:MGI:5623822 +105245490 Gm40938 MGI:MGI:5623823 +105245491 Gm40939 MGI:MGI:5623824 +105245492 Gm40940 MGI:MGI:5623825 +105245493 Gm40941 MGI:MGI:5623826 +105245494 Gm40942 MGI:MGI:5623827 +105245495 Gm40943 MGI:MGI:5623828 +105245496 Gm40944 MGI:MGI:5623829 +105245497 Gm40945 MGI:MGI:5623830 +105245498 Gm40946 MGI:MGI:5623831 +105245499 Gm40947 MGI:MGI:5623832 +105245500 Gm40948 MGI:MGI:5623833 +105245501 Gm40949 MGI:MGI:5623834 +105245502 Gm40950 MGI:MGI:5623835 +105245503 Gm40951 MGI:MGI:5623836 +105245504 Gm40952 MGI:MGI:5623837 +105245505 Gm40953 MGI:MGI:5623838 +105245506 Gm40954 MGI:MGI:5623839 +105245507 Gm40955 MGI:MGI:5623840 +105245508 Gm16578 MGI:MGI:4414998 +105245510 Gm40957 MGI:MGI:5623842 +105245511 Gm40958 MGI:MGI:5623843 +105245512 Gm40959 MGI:MGI:5623844 +105245513 Gm40960 MGI:MGI:5623845 +105245514 Gm40961 MGI:MGI:5623846 +105245515 Gm40962 MGI:MGI:5623847 +105245516 LOC105245516 - +105245517 Gm40963 MGI:MGI:5623848 +105245518 Gm40964 MGI:MGI:5623849 +105245519 Gm40965 MGI:MGI:5623850 +105245520 Gm40966 MGI:MGI:5623851 +105245521 Gm40967 MGI:MGI:5623852 +105245522 Gm40968 MGI:MGI:5623853 +105245523 Gm40969 MGI:MGI:5623854 +105245524 Gm40970 MGI:MGI:5623855 +105245525 Gm40971 MGI:MGI:5623856 +105245526 Gm40972 MGI:MGI:5623857 +105245528 Gm40973 MGI:MGI:5623858 +105245529 Gm40974 MGI:MGI:5623859 +105245530 Gm40975 MGI:MGI:5623860 +105245531 Gm40976 MGI:MGI:5623861 +105245532 Gm40977 MGI:MGI:5623862 +105245533 Gm40978 MGI:MGI:5623863 +105245534 Gm40979 MGI:MGI:5623864 +105245535 Gm40980 MGI:MGI:5623865 +105245536 Gm40981 MGI:MGI:5623866 +105245537 Gm40982 MGI:MGI:5623867 +105245538 Gm40983 MGI:MGI:5623868 +105245539 Gm40984 MGI:MGI:5623869 +105245540 Gm40985 MGI:MGI:5623870 +105245541 Gm40986 MGI:MGI:5623871 +105245542 Gm40987 MGI:MGI:5623872 +105245543 Gm40988 MGI:MGI:5623873 +105245544 Gm40989 MGI:MGI:5623874 +105245545 Gm10323 MGI:MGI:3809062 +105245546 Gm40990 MGI:MGI:5623875 +105245547 Gm40991 MGI:MGI:5623876 +105245548 Gm40992 MGI:MGI:5623877 +105245549 Gm40993 MGI:MGI:5623878 +105245550 Gm40994 MGI:MGI:5623879 +105245551 Gm40995 MGI:MGI:5623880 +105245552 Gm40996 MGI:MGI:5623881 +105245553 Gm40997 MGI:MGI:5623882 +105245554 Gm40998 MGI:MGI:5623883 +105245555 Gm40999 MGI:MGI:5623884 +105245556 Gm41000 MGI:MGI:5623885 +105245557 Gm41001 MGI:MGI:5623886 +105245558 Gm41002 MGI:MGI:5623887 +105245559 Gm41003 MGI:MGI:5623888 +105245560 Gm16125 MGI:MGI:3802000 +105245561 Gm41004 MGI:MGI:5623889 +105245562 LOC105245562 - +105245563 Gm41005 MGI:MGI:5623890 +105245564 Gm41006 MGI:MGI:5623891 +105245565 Gm41007 MGI:MGI:5623892 +105245566 LOC105245566 - +105245567 Gm41008 MGI:MGI:5623893 +105245568 Gm41009 MGI:MGI:5623894 +105245569 Gm41010 MGI:MGI:5623895 +105245570 Gm26803 MGI:MGI:5477297 +105245571 Gm41011 MGI:MGI:5623896 +105245572 Gm41012 MGI:MGI:5623897 +105245573 Gm41013 MGI:MGI:5623898 +105245574 Gm41014 MGI:MGI:5623899 +105245575 Gm41015 MGI:MGI:5623900 +105245576 Gm41016 MGI:MGI:5623901 +105245577 LOC105245577 - +105245578 LOC105245578 - +105245579 Gm41017 MGI:MGI:5623902 +105245580 LOC105245580 - +105245585 LOC105245585 - +105245586 Gm41018 MGI:MGI:5623903 +105245587 Gm41019 MGI:MGI:5623904 +105245588 Gm41020 MGI:MGI:5623905 +105245589 Gm41021 MGI:MGI:5623906 +105245590 Gm41022 MGI:MGI:5623907 +105245591 Gm41023 MGI:MGI:5623908 +105245592 Gm41024 MGI:MGI:5623909 +105245593 Gm41025 MGI:MGI:5623910 +105245594 Gm41026 MGI:MGI:5623911 +105245595 Gm29543 MGI:MGI:5580249 +105245596 Gm41027 MGI:MGI:5623912 +105245597 Gm41028 MGI:MGI:5623913 +105245598 Gm41029 MGI:MGI:5623914 +105245599 Gm41030 MGI:MGI:5623915 +105245600 Gm41031 MGI:MGI:5623916 +105245601 Gm41032 MGI:MGI:5623917 +105245602 Gm41033 MGI:MGI:5623918 +105245603 Gm41034 MGI:MGI:5623919 +105245604 Gm41035 MGI:MGI:5623920 +105245605 Gm41036 MGI:MGI:5623921 +105245606 Gm41037 MGI:MGI:5623922 +105245607 Gm41038 MGI:MGI:5623923 +105245608 Gm41039 MGI:MGI:5623924 +105245610 Gm41040 MGI:MGI:5623925 +105245611 Gm41041 MGI:MGI:5623926 +105245612 Gm41042 MGI:MGI:5623927 +105245613 Gm41043 MGI:MGI:5623928 +105245614 Gm41044 MGI:MGI:5623929 +105245615 Gm41045 MGI:MGI:5623930 +105245616 Gm41046 MGI:MGI:5623931 +105245617 Gm41047 MGI:MGI:5623932 +105245618 Gm41048 MGI:MGI:5623933 +105245619 Gm41049 MGI:MGI:5623934 +105245620 Gm41050 MGI:MGI:5623935 +105245621 Gm41051 MGI:MGI:5623936 +105245622 Gm41052 MGI:MGI:5623937 +105245623 Gm22118 MGI:MGI:5451895 +105245624 Gm41053 MGI:MGI:5623938 +105245625 Gm41054 MGI:MGI:5623939 +105245626 Gm41055 MGI:MGI:5623940 +105245627 Gm41056 MGI:MGI:5623941 +105245628 Gm41057 MGI:MGI:5623942 +105245629 Gm41058 MGI:MGI:5623943 +105245630 Gm41059 MGI:MGI:5623944 +105245631 Gm15286 MGI:MGI:3705204|Ensembl:ENSMUSG00000086649 +105245632 Gm41060 MGI:MGI:5623945 +105245633 Gm41061 MGI:MGI:5623946 +105245634 Gm41062 MGI:MGI:5623947 +105245635 Gm41063 MGI:MGI:5623948 +105245636 Gm41064 MGI:MGI:5623949 +105245637 Gm41065 MGI:MGI:5623950 +105245638 Gm41066 MGI:MGI:5623951 +105245639 Gm41067 MGI:MGI:5623952 +105245640 Gm41068 MGI:MGI:5623953 +105245641 Gm41069 MGI:MGI:5623954 +105245642 Gm41070 MGI:MGI:5623955 +105245643 Gm41071 MGI:MGI:5623956 +105245644 Gm41072 MGI:MGI:5623957 +105245645 Gm41073 MGI:MGI:5623958 +105245646 Gm41074 MGI:MGI:5623959 +105245647 Gm41075 MGI:MGI:5623960 +105245648 LOC105245648 - +105245649 Gm41076 MGI:MGI:5623961 +105245650 Gm41077 MGI:MGI:5623962 +105245651 LOC105245651 - +105245652 Gm41078 MGI:MGI:5623963 +105245653 Gm41079 MGI:MGI:5623964 +105245654 Gm41080 MGI:MGI:5623965 +105245655 Gm41081 MGI:MGI:5623966 +105245657 Gm41082 MGI:MGI:5623967 +105245659 Gm41083 MGI:MGI:5623968 +105245661 Gm41084 MGI:MGI:5623969 +105245662 Gm41085 MGI:MGI:5623970 +105245663 Gm41086 MGI:MGI:5623971 +105245664 Gm41087 MGI:MGI:5623972 +105245665 Gm3542 MGI:MGI:3781719 +105245666 Gm41088 MGI:MGI:5623973 +105245667 Gm41089 MGI:MGI:5623974 +105245668 Gm26650 MGI:MGI:5477144 +105245669 Gm41090 MGI:MGI:5623975 +105245670 Gm41091 MGI:MGI:5623976 +105245672 Gm41092 MGI:MGI:5623977 +105245673 LOC105245673 Ensembl:ENSMUSG00000096869|Vega:OTTMUSG00000035709 +105245674 Gm41093 MGI:MGI:5623978 +105245675 LOC105245675 Ensembl:ENSMUSG00000094460|Vega:OTTMUSG00000036272 +105245676 Gm26991 MGI:MGI:5504106 +105245677 Gm41094 MGI:MGI:5623979 +105245678 Gm41095 MGI:MGI:5623980 +105245679 Gm41096 MGI:MGI:5623981 +105245680 Gm41097 MGI:MGI:5623982 +105245681 Gm41098 MGI:MGI:5623983 +105245682 Gm41099 MGI:MGI:5623984 +105245683 Gm41100 MGI:MGI:5623985 +105245684 Gm3012 MGI:MGI:3781190|Ensembl:ENSMUSG00000095368|Vega:OTTMUSG00000036013 +105245688 Gm41101 MGI:MGI:5623986 +105245689 Gm41102 MGI:MGI:5623987 +105245690 Gm41103 MGI:MGI:5623988 +105245691 Gm17030 MGI:MGI:4937857 +105245692 Gm41104 MGI:MGI:5623989 +105245693 Gm41105 MGI:MGI:5623990 +105245694 Gm41106 MGI:MGI:5623991 +105245695 Gm41107 MGI:MGI:5623992 +105245696 LOC105245696 - +105245697 Gm41108 MGI:MGI:5623993 +105245698 Gm41109 MGI:MGI:5623994 +105245699 Gm41110 MGI:MGI:5623995 +105245700 Gm41111 MGI:MGI:5623996 +105245701 Gm41112 MGI:MGI:5623997 +105245702 Gm41113 MGI:MGI:5623998 +105245705 Anxa11os MGI:MGI:3642737 +105245706 Gm41114 MGI:MGI:5623999 +105245707 Gm41115 MGI:MGI:5624000 +105245708 Gm41116 MGI:MGI:5624001 +105245709 Gm41117 MGI:MGI:5624002 +105245710 Gm41118 MGI:MGI:5624003 +105245711 Gm41119 MGI:MGI:5624004 +105245712 Gm41120 MGI:MGI:5624005 +105245713 Gm41121 MGI:MGI:5624006 +105245715 Gm41123 MGI:MGI:5624008 +105245716 Gm41124 MGI:MGI:5624009 +105245717 Gm41125 MGI:MGI:5624010 +105245718 Gm41126 MGI:MGI:5624011 +105245719 Gm41127 MGI:MGI:5624012 +105245720 Gm17210 MGI:MGI:4938037 +105245722 Gm41128 MGI:MGI:5624013 +105245723 Gm41129 MGI:MGI:5624014 +105245724 Gm41130 MGI:MGI:5624015 +105245727 Gm41131 MGI:MGI:5624016 +105245729 Gm41132 MGI:MGI:5624017 +105245730 Gm41133 MGI:MGI:5624018 +105245731 Gm41134 MGI:MGI:5624019 +105245732 Gm41135 MGI:MGI:5624020 +105245734 LOC105245734 - +105245736 Gm41136 MGI:MGI:5624021 +105245737 LOC105245737 - +105245738 Gm41137 MGI:MGI:5624022 +105245739 Gm41138 MGI:MGI:5624023 +105245740 Gm41139 MGI:MGI:5624024 +105245741 Gm41140 MGI:MGI:5624025 +105245742 Gm41141 MGI:MGI:5624026 +105245743 Gm41142 MGI:MGI:5624027 +105245744 Gm41143 MGI:MGI:5624028 +105245745 Gm41144 MGI:MGI:5624029 +105245746 Gm41145 MGI:MGI:5624030 +105245747 Gm41146 MGI:MGI:5624031 +105245748 Gm41147 MGI:MGI:5624032 +105245749 Gm41148 MGI:MGI:5624033 +105245750 Gm41149 MGI:MGI:5624034 +105245751 Gm41150 MGI:MGI:5624035 +105245752 Gm41151 MGI:MGI:5624036 +105245753 Gm41152 MGI:MGI:5624037 +105245754 Gm41153 MGI:MGI:5624038 +105245755 Gm41154 MGI:MGI:5624039 +105245756 Gm41155 MGI:MGI:5624040 +105245757 Gm41156 MGI:MGI:5624041 +105245758 Gm41157 MGI:MGI:5624042 +105245759 Gm41158 MGI:MGI:5624043 +105245760 Gm41159 MGI:MGI:5624044 +105245761 Gm41160 MGI:MGI:5624045 +105245762 Gm41161 MGI:MGI:5624046 +105245764 Gm41162 MGI:MGI:5624047 +105245765 Gm41163 MGI:MGI:5624048 +105245766 Gm41164 MGI:MGI:5624049 +105245767 LOC105245767 - +105245768 Gm41165 MGI:MGI:5624050 +105245769 Gm41166 MGI:MGI:5624051 +105245770 Gm29266 MGI:MGI:5579972 +105245771 Gm41167 MGI:MGI:5624052 +105245772 Gm41168 MGI:MGI:5624053 +105245773 Gm41169 MGI:MGI:5624054 +105245774 Gm41170 MGI:MGI:5624055 +105245775 Gm41171 MGI:MGI:5624056 +105245776 Gm41172 MGI:MGI:5624057 +105245777 Gm41173 MGI:MGI:5624058 +105245778 Gm41174 MGI:MGI:5624059 +105245779 Gm17232 MGI:MGI:4938059 +105245780 Gm15918 MGI:MGI:3801738 +105245781 Gm41175 MGI:MGI:5624060 +105245782 Gm41176 MGI:MGI:5624061 +105245783 LOC105245783 - +105245784 Gm41177 MGI:MGI:5624062 +105245785 LOC105245785 - +105245786 Gm41178 MGI:MGI:5624063 +105245787 Gm41179 MGI:MGI:5624064 +105245788 Gm41180 MGI:MGI:5624065 +105245789 Gm41181 MGI:MGI:5624066 +105245790 Gm41182 MGI:MGI:5624067 +105245791 Gm41183 MGI:MGI:5624068 +105245792 Gm41184 MGI:MGI:5624069 +105245793 Gm41185 MGI:MGI:5624070 +105245794 Gm41186 MGI:MGI:5624071 +105245795 Gm20675 MGI:MGI:5313122 +105245796 Gm41187 MGI:MGI:5624072 +105245797 Gm41188 MGI:MGI:5624073 +105245798 Gm41189 MGI:MGI:5624074 +105245799 Gm41190 MGI:MGI:5624075 +105245800 Gm41191 MGI:MGI:5624076 +105245801 Gm41192 MGI:MGI:5624077 +105245802 Gm37762 MGI:MGI:5610990 +105245803 Gm41193 MGI:MGI:5624078 +105245804 Gm41194 MGI:MGI:5624079 +105245805 Gm41195 MGI:MGI:5624080 +105245806 Gm41196 MGI:MGI:5624081 +105245807 Gm41197 MGI:MGI:5624082 +105245808 Gm41198 MGI:MGI:5624083 +105245809 Gm41199 MGI:MGI:5624084 +105245810 Gm41200 MGI:MGI:5624085 +105245811 Gm41201 MGI:MGI:5624086 +105245812 Gm41202 MGI:MGI:5624087 +105245813 Gm41203 MGI:MGI:5624088 +105245814 Gm41204 MGI:MGI:5624089 +105245815 Gm41205 MGI:MGI:5624090 +105245816 Gm41206 MGI:MGI:5624091 +105245817 Gm41207 MGI:MGI:5624092 +105245818 Gm41208 MGI:MGI:5624093 +105245819 Gm41209 MGI:MGI:5624094 +105245820 Gm41210 MGI:MGI:5624095 +105245821 Gm41211 MGI:MGI:5624096 +105245822 Gm41212 MGI:MGI:5624097 +105245823 Gm41213 MGI:MGI:5624098 +105245824 Gm41214 MGI:MGI:5624099 +105245825 Gm41215 MGI:MGI:5624100 +105245826 Gm41216 MGI:MGI:5624101 +105245827 Gm41217 MGI:MGI:5624102 +105245828 Gm41218 MGI:MGI:5624103 +105245829 Gm41219 MGI:MGI:5624104 +105245830 Gm41220 MGI:MGI:5624105 +105245831 Gm41221 MGI:MGI:5624106 +105245832 Gm41222 MGI:MGI:5624107 +105245833 Gm41223 MGI:MGI:5624108 +105245834 Gm41224 MGI:MGI:5624109 +105245835 LOC105245835 - +105245836 Gm41225 MGI:MGI:5624110 +105245837 Gm41226 MGI:MGI:5624111 +105245838 Gm41227 MGI:MGI:5624112 +105245839 Gm41228 MGI:MGI:5624113 +105245840 Gm41229 MGI:MGI:5624114 +105245841 Gm41230 MGI:MGI:5624115 +105245842 Gm41231 MGI:MGI:5624116 +105245843 Gm41232 MGI:MGI:5624117 +105245844 Gm41233 MGI:MGI:5624118 +105245845 Gm41234 MGI:MGI:5624119 +105245846 Gm41235 MGI:MGI:5624120 +105245847 Gm41236 MGI:MGI:5624121 +105245848 Gm41237 MGI:MGI:5624122 +105245849 Gm41238 MGI:MGI:5624123 +105245850 Gm41239 MGI:MGI:5624124 +105245851 Gm41240 MGI:MGI:5624125 +105245852 Gm41241 MGI:MGI:5624126 +105245853 Gm41242 MGI:MGI:5624127 +105245854 Gm41243 MGI:MGI:5624128 +105245855 Gm41244 MGI:MGI:5624129 +105245856 Gm41245 MGI:MGI:5624130 +105245857 Gm41246 MGI:MGI:5624131 +105245858 Gm41247 MGI:MGI:5624132 +105245859 Gm41248 MGI:MGI:5624133 +105245860 LOC105245860 - +105245861 Gm41249 MGI:MGI:5624134 +105245862 Gm41250 MGI:MGI:5624135 +105245863 Gm41251 MGI:MGI:5624136 +105245864 Gm41252 MGI:MGI:5624137 +105245865 Gm41253 MGI:MGI:5624138 +105245866 Gm15735 MGI:MGI:3783177|Ensembl:ENSMUSG00000075463 +105245868 Gm25380 MGI:MGI:5455157 +105245869 LOC105245869 Ensembl:ENSMUSG00000090534 +105245870 Gm41254 MGI:MGI:5624139 +105245871 Gm41255 MGI:MGI:5624140 +105245872 Gm41256 MGI:MGI:5624141 +105245873 Gm15938 MGI:MGI:3801775 +105245874 Gm41257 MGI:MGI:5624142 +105245875 Gm41258 MGI:MGI:5624143 +105245876 Gm41259 MGI:MGI:5624144 +105245877 Gm41260 MGI:MGI:5624145 +105245878 Gm41261 MGI:MGI:5624146 +105245879 Gm41262 MGI:MGI:5624147 +105245880 Gm41263 MGI:MGI:5624148 +105245881 Gm41264 MGI:MGI:5624149 +105245882 LOC105245882 - +105245883 Gm41265 MGI:MGI:5624150 +105245884 Gm41266 MGI:MGI:5624151 +105245885 Gm41267 MGI:MGI:5624152 +105245886 Gm41268 MGI:MGI:5624153 +105245887 Gm41269 MGI:MGI:5624154 +105245888 Gm41270 MGI:MGI:5624155 +105245890 Gm41271 MGI:MGI:5624156 +105245891 Gm41272 MGI:MGI:5624157 +105245892 Gm41273 MGI:MGI:5624158 +105245893 Gm41274 MGI:MGI:5624159 +105245894 Gm41275 MGI:MGI:5624160 +105245895 Gm41276 MGI:MGI:5624161 +105245896 Gm41277 MGI:MGI:5624162 +105245897 Gm41278 MGI:MGI:5624163 +105245898 Gm41279 MGI:MGI:5624164 +105245899 LOC105245899 - +105245900 Gm41280 MGI:MGI:5624165 +105245901 Gm41281 MGI:MGI:5624166 +105245902 Gm41282 MGI:MGI:5624167 +105245903 Gm41283 MGI:MGI:5624168 +105245904 Gm41284 MGI:MGI:5624169 +105245905 Gm41285 MGI:MGI:5624170 +105245906 Gm41286 MGI:MGI:5624171 +105245907 Gm41287 MGI:MGI:5624172 +105245908 Gm41288 MGI:MGI:5624173 +105245909 Gm41289 MGI:MGI:5624174 +105245910 Gm41290 MGI:MGI:5624175 +105245911 Gm41291 MGI:MGI:5624176 +105245912 Gm41292 MGI:MGI:5624177 +105245913 Gm41293 MGI:MGI:5624178 +105245914 Gm41294 MGI:MGI:5624179 +105245915 Gm41295 MGI:MGI:5624180 +105245916 Gm41296 MGI:MGI:5624181 +105245917 Gm41297 MGI:MGI:5624182 +105245918 Gm41298 MGI:MGI:5624183 +105245919 Gm41299 MGI:MGI:5624184 +105245920 Gm41300 MGI:MGI:5624185 +105245921 Gm41301 MGI:MGI:5624186 +105245922 Gm41302 MGI:MGI:5624187 +105245923 Gm41303 MGI:MGI:5624188 +105245924 LOC105245924 Ensembl:ENSMUSG00000089804 +105245925 Gm15942 MGI:MGI:3802083 +105245926 Gm41304 MGI:MGI:5624189 +105245927 Gm41305 MGI:MGI:5624190 +105245928 Gm41306 MGI:MGI:5624191 +105245929 Gm41307 MGI:MGI:5624192 +105245930 Gm41308 MGI:MGI:5624193 +105245931 Gm41309 MGI:MGI:5624194 +105245937 Gm41310 MGI:MGI:5624195 +105245938 Gm26704 MGI:MGI:5477198 +105245939 Gm41311 MGI:MGI:5624196 +105245940 Gm41312 MGI:MGI:5624197 +105245941 Gm41313 MGI:MGI:5624198 +105245942 Gm41314 MGI:MGI:5624199 +105245943 Gm41315 MGI:MGI:5624200 +105245944 Gm41316 MGI:MGI:5624201 +105245945 Gm41317 MGI:MGI:5624202 +105245946 Gm41318 MGI:MGI:5624203 +105245947 Gm41319 MGI:MGI:5624204 +105245948 Gm41320 MGI:MGI:5624205 +105245949 Gm41321 MGI:MGI:5624206 +105245950 Gm41322 MGI:MGI:5624207 +105245951 Gm41323 MGI:MGI:5624208 +105245952 Gm41324 MGI:MGI:5624209 +105245953 Gm41325 MGI:MGI:5624210 +105245954 Gm41326 MGI:MGI:5624211 +105245955 Gm41327 MGI:MGI:5624212 +105245956 Gm41328 MGI:MGI:5624213 +105245957 Gm16006 MGI:MGI:3801853 +105245958 Gm41329 MGI:MGI:5624214 +105245959 Gm41330 MGI:MGI:5624215 +105245960 Gm41331 MGI:MGI:5624216 +105245961 Gm41332 MGI:MGI:5624217 +105245962 Gm41333 MGI:MGI:5624218 +105245963 Gm41334 MGI:MGI:5624219 +105245964 Gm41335 MGI:MGI:5624220 +105245965 Gm41336 MGI:MGI:5624221 +105245966 Gm41337 MGI:MGI:5624222 +105245967 Gm41338 MGI:MGI:5624223 +105245968 Gm41339 MGI:MGI:5624224 +105245969 Gm41340 MGI:MGI:5624225 +105245970 LOC105245970 - +105245971 Gm41341 MGI:MGI:5624226 +105245972 Gm41342 MGI:MGI:5624227 +105245973 Gm16308 MGI:MGI:3826592 +105245974 Gm41343 MGI:MGI:5624228 +105245975 Gm41344 MGI:MGI:5624229 +105245976 Gm41345 MGI:MGI:5624230 +105245977 Gm41346 MGI:MGI:5624231 +105245978 LOC105245978 - +105245979 Gm41347 MGI:MGI:5624232 +105245980 Gm41348 MGI:MGI:5624233 +105245981 Gm41349 MGI:MGI:5624234 +105245982 Gm41350 MGI:MGI:5624235 +105245983 Gm41351 MGI:MGI:5624236 +105245984 Gm41352 MGI:MGI:5624237 +105245985 Gm41353 MGI:MGI:5624238 +105245986 Gm41354 MGI:MGI:5624239 +105245987 Gm41355 MGI:MGI:5624240 +105245988 Gm41356 MGI:MGI:5624241 +105245989 Gm41357 MGI:MGI:5624242 +105245990 Gm20420 MGI:MGI:5141885 +105245991 Gm41358 MGI:MGI:5624243 +105245992 Gm41359 MGI:MGI:5624244 +105245993 Gm41360 MGI:MGI:5624245 +105245994 Gm41361 MGI:MGI:5624246 +105245995 Gm41362 MGI:MGI:5624247 +105245996 Gm41363 MGI:MGI:5624248 +105245997 Gm41364 MGI:MGI:5624249 +105245998 Gm41365 MGI:MGI:5624250 +105245999 Gm41366 MGI:MGI:5624251 +105246000 Gm41367 MGI:MGI:5624252 +105246001 Gm41368 MGI:MGI:5624253 +105246002 Gm41369 MGI:MGI:5624254 +105246003 Gm41370 MGI:MGI:5624255 +105246004 Gm41371 MGI:MGI:5624256 +105246005 Gm41372 MGI:MGI:5624257 +105246006 Gm41373 MGI:MGI:5624258 +105246007 Gm41374 MGI:MGI:5624259 +105246008 Gm15722 MGI:MGI:3783166 +105246009 Gm41375 MGI:MGI:5624260 +105246010 Gm41376 MGI:MGI:5624261 +105246011 LOC105246011 - +105246012 Gm41377 MGI:MGI:5624262 +105246013 Gm41378 MGI:MGI:5624263 +105246014 Gm41379 MGI:MGI:5624264 +105246015 Gm41380 MGI:MGI:5624265 +105246016 LOC105246016 - +105246017 Gm41381 MGI:MGI:5624266 +105246018 LOC105246018 - +105246019 Gm41382 MGI:MGI:5624267 +105246020 Gm26760 MGI:MGI:5477254 +105246021 Gm41383 MGI:MGI:5624268 +105246022 Gm41384 MGI:MGI:5624269 +105246023 Gm41385 MGI:MGI:5624270 +105246024 Gm41386 MGI:MGI:5624271 +105246025 Gm41387 MGI:MGI:5624272 +105246026 Gm41388 MGI:MGI:5624273 +105246027 Gm41389 MGI:MGI:5624274 +105246028 Gm41390 MGI:MGI:5624275 +105246029 Gm41391 MGI:MGI:5624276 +105246030 Gm41392 MGI:MGI:5624277 +105246031 Gm41393 MGI:MGI:5624278 +105246032 Gm41394 MGI:MGI:5624279 +105246033 Gm41395 MGI:MGI:5624280 +105246034 LOC105246034 - +105246035 Gm41396 MGI:MGI:5624281 +105246036 Gm41397 MGI:MGI:5624282 +105246037 Gm41398 MGI:MGI:5624283 +105246038 Gm41399 MGI:MGI:5624284 +105246039 Gm41400 MGI:MGI:5624285 +105246040 LOC105246040 - +105246041 Gm41401 MGI:MGI:5624286 +105246042 Gm41402 MGI:MGI:5624287 +105246043 Gm41403 MGI:MGI:5624288 +105246044 Gm41404 MGI:MGI:5624289 +105246045 Gm41405 MGI:MGI:5624290 +105246046 LOC105246046 - +105246047 Gm41406 MGI:MGI:5624291 +105246048 Gm41407 MGI:MGI:5624292 +105246049 Gm41408 MGI:MGI:5624293 +105246056 LOC105246056 Ensembl:ENSMUSG00000048603 +105246058 Gm41409 MGI:MGI:5624294 +105246059 Gm41410 MGI:MGI:5624295 +105246060 Gm41411 MGI:MGI:5624296 +105246061 Gm41412 MGI:MGI:5624297 +105246062 LOC105246062 - +105246063 Gm41413 MGI:MGI:5624298 +105246064 Gm41414 MGI:MGI:5624299 +105246065 Gm41415 MGI:MGI:5624300 +105246066 Gm41416 MGI:MGI:5624301 +105246067 Gm41417 MGI:MGI:5624302 +105246068 Gm41418 MGI:MGI:5624303 +105246069 Gm41419 MGI:MGI:5624304 +105246070 Gm41420 MGI:MGI:5624305 +105246071 LOC105246071 - +105246073 Gm41421 MGI:MGI:5624306 +105246074 Gm41422 MGI:MGI:5624307 +105246075 Gm41423 MGI:MGI:5624308 +105246076 Gm41424 MGI:MGI:5624309 +105246077 Gm41425 MGI:MGI:5624310 +105246078 LOC105246078 - +105246079 Gm41426 MGI:MGI:5624311 +105246080 Gm41427 MGI:MGI:5624312 +105246081 Gm41428 MGI:MGI:5624313 +105246082 Gm41429 MGI:MGI:5624314 +105246083 Gm41430 MGI:MGI:5624315 +105246084 Gm41431 MGI:MGI:5624316 +105246085 Gm41432 MGI:MGI:5624317 +105246086 Gm26744 MGI:MGI:5477238 +105246087 Gm41433 MGI:MGI:5624318 +105246089 LOC105246089 - +105246090 Gm41434 MGI:MGI:5624319 +105246091 Gm41435 MGI:MGI:5624320 +105246092 Gm41436 MGI:MGI:5624321 +105246093 Gm41437 MGI:MGI:5624322 +105246094 Gm41438 MGI:MGI:5624323 +105246095 Gm26562 MGI:MGI:5477056 +105246096 Gm41439 MGI:MGI:5624324 +105246097 Gm41440 MGI:MGI:5624325 +105246098 Gm41441 MGI:MGI:5624326 +105246099 Gm41442 MGI:MGI:5624327 +105246100 Gm41443 MGI:MGI:5624328 +105246101 Gm41444 MGI:MGI:5624329 +105246102 Gm41445 MGI:MGI:5624330 +105246103 Gm41446 MGI:MGI:5624331 +105246104 Gm41447 MGI:MGI:5624332 +105246105 Gm41448 MGI:MGI:5624333 +105246106 LOC105246106 - +105246107 Gm41449 MGI:MGI:5624334 +105246108 Gm41450 MGI:MGI:5624335 +105246109 Gm41451 MGI:MGI:5624336 +105246110 Gm41452 MGI:MGI:5624337 +105246111 Gm41453 MGI:MGI:5624338 +105246112 Gm41454 MGI:MGI:5624339 +105246113 Gm41455 MGI:MGI:5624340 +105246114 LOC105246114 - +105246115 Gm41456 MGI:MGI:5624341 +105246116 Gm41457 MGI:MGI:5624342 +105246117 Gm41458 MGI:MGI:5624343 +105246118 Gm41459 MGI:MGI:5624344 +105246119 Gm41460 MGI:MGI:5624345 +105246120 Gm41461 MGI:MGI:5624346 +105246121 Gm41462 MGI:MGI:5624347 +105246122 Gm26800 MGI:MGI:5477294 +105246123 Gm41463 MGI:MGI:5624348 +105246124 Gm41464 MGI:MGI:5624349 +105246125 Gm41465 MGI:MGI:5624350 +105246126 Gm41466 MGI:MGI:5624351 +105246127 Gm41467 MGI:MGI:5624352 +105246128 Gm41468 MGI:MGI:5624353 +105246129 Gm15597 MGI:MGI:3783044 +105246130 Gm41469 MGI:MGI:5624354 +105246131 Gm41470 MGI:MGI:5624355 +105246132 Gm41471 MGI:MGI:5624356 +105246133 Gm41472 MGI:MGI:5624357 +105246135 Gm41473 MGI:MGI:5624358 +105246136 Gm41474 MGI:MGI:5624359 +105246137 Gm41475 MGI:MGI:5624360 +105246138 Gm41476 MGI:MGI:5624361 +105246140 Gm41477 MGI:MGI:5624362 +105246142 Gm41478 MGI:MGI:5624363 +105246143 Gm41479 MGI:MGI:5624364 +105246144 Gm41480 MGI:MGI:5624365 +105246145 Gm41481 MGI:MGI:5624366 +105246146 Gm41482 MGI:MGI:5624367 +105246147 Gm41483 MGI:MGI:5624368 +105246148 Gm41484 MGI:MGI:5624369 +105246149 Gm41485 MGI:MGI:5624370 +105246150 Gm41486 MGI:MGI:5624371 +105246151 LOC105246151 - +105246152 Gm41487 MGI:MGI:5624372 +105246153 Gm41488 MGI:MGI:5624373 +105246154 Gm41489 MGI:MGI:5624374 +105246155 Gm41490 MGI:MGI:5624375 +105246157 Gm41491 MGI:MGI:5624376 +105246158 Gm41492 MGI:MGI:5624377 +105246159 Gm41493 MGI:MGI:5624378 +105246160 Gm41494 MGI:MGI:5624379 +105246161 Gm41495 MGI:MGI:5624380 +105246162 Gm41496 MGI:MGI:5624381 +105246163 Gm41497 MGI:MGI:5624382 +105246164 Gm41498 MGI:MGI:5624383 +105246165 Gm41499 MGI:MGI:5624384 +105246166 Gm41500 MGI:MGI:5624385 +105246167 Gm41501 MGI:MGI:5624386 +105246168 Gm41502 MGI:MGI:5624387 +105246169 Gm41503 MGI:MGI:5624388 +105246170 Gm41504 MGI:MGI:5624389 +105246171 Gm41505 MGI:MGI:5624390 +105246172 Gm41506 MGI:MGI:5624391 +105246173 Gm41507 MGI:MGI:5624392 +105246174 Gm41508 MGI:MGI:5624393 +105246175 Gm41509 MGI:MGI:5624394 +105246176 Gm41510 MGI:MGI:5624395 +105246177 Gm41511 MGI:MGI:5624396 +105246178 Gm41512 MGI:MGI:5624397 +105246179 Gm41513 MGI:MGI:5624398 +105246180 Gm41514 MGI:MGI:5624399 +105246181 Gm41515 MGI:MGI:5624400 +105246182 Gm41516 MGI:MGI:5624401 +105246183 Gm41517 MGI:MGI:5624402 +105246184 Gm41518 MGI:MGI:5624403 +105246185 Gm41519 MGI:MGI:5624404 +105246186 LOC105246186 - +105246187 Gm41520 MGI:MGI:5624405 +105246188 Gm41521 MGI:MGI:5624406 +105246189 Gm41522 MGI:MGI:5624407 +105246190 Gm41523 MGI:MGI:5624408 +105246191 Gm41524 MGI:MGI:5624409 +105246192 Gm41525 MGI:MGI:5624410 +105246193 Gm41526 MGI:MGI:5624411 +105246194 Gm28505 MGI:MGI:5579211 +105246195 Gm41527 MGI:MGI:5624412 +105246196 Gm41528 MGI:MGI:5624413 +105246197 Gm41529 MGI:MGI:5624414 +105246205 LOC105246205 - +105246216 Gm41530 MGI:MGI:5624415 +105246217 Gm16046 MGI:MGI:3802093 +105246218 Gm41531 MGI:MGI:5624416 +105246219 Gm41532 MGI:MGI:5624417 +105246220 Gm41533 MGI:MGI:5624418 +105246221 Gm41534 MGI:MGI:5624419 +105246222 Gm41535 MGI:MGI:5624420 +105246223 Gm26873 MGI:MGI:5477367 +105246224 Gm41536 MGI:MGI:5624421 +105246225 Gm41537 MGI:MGI:5624422 +105246226 Gm41538 MGI:MGI:5624423 +105246227 Gm41539 MGI:MGI:5624424 +105246228 Gm41540 MGI:MGI:5624425 +105246229 Gm41541 MGI:MGI:5624426 +105246230 Gm41542 MGI:MGI:5624427 +105246231 Gm41543 MGI:MGI:5624428 +105246232 Gm41544 MGI:MGI:5624429 +105246233 Gm41545 MGI:MGI:5624430 +105246234 Gm41546 MGI:MGI:5624431 +105246235 Gm41547 MGI:MGI:5624432 +105246236 Gm41548 MGI:MGI:5624433 +105246237 Gm41549 MGI:MGI:5624434 +105246238 Gm41550 MGI:MGI:5624435 +105246239 Gm41551 MGI:MGI:5624436 +105246240 Gm41552 MGI:MGI:5624437 +105246241 Gm41553 MGI:MGI:5624438 +105246242 Gm41554 MGI:MGI:5624439 +105246243 Gm41555 MGI:MGI:5624440 +105246244 LOC105246244 - +105246245 LOC105246245 - +105246246 Gm16191 MGI:MGI:3801759 +105246247 Gm16196 MGI:MGI:3801772 +105246248 Gm41556 MGI:MGI:5624441 +105246249 Gm41557 MGI:MGI:5624442 +105246250 Gm41558 MGI:MGI:5624443 +105246251 Gm41559 MGI:MGI:5624444 +105246252 Gm41560 MGI:MGI:5624445 +105246253 Gm41561 MGI:MGI:5624446 +105246254 Gm41562 MGI:MGI:5624447 +105246255 Gm41563 MGI:MGI:5624448 +105246256 Gm41564 MGI:MGI:5624449 +105246257 Gm41565 MGI:MGI:5624450 +105246258 Gm41566 MGI:MGI:5624451 +105246259 Gm41567 MGI:MGI:5624452 +105246260 Gm41568 MGI:MGI:5624453 +105246261 Gm41569 MGI:MGI:5624454 +105246262 Gm41570 MGI:MGI:5624455 +105246263 Gm41571 MGI:MGI:5624456 +105246264 Gm41572 MGI:MGI:5624457 +105246265 Gm41573 MGI:MGI:5624458 +105246266 Gm41574 MGI:MGI:5624459 +105246267 Gm41575 MGI:MGI:5624460 +105246268 Gm15331 MGI:MGI:3705549 +105246269 Gm41576 MGI:MGI:5624461 +105246270 Gm41577 MGI:MGI:5624462 +105246271 LOC105246271 - +105246272 Gm41578 MGI:MGI:5624463 +105246273 Gm41579 MGI:MGI:5624464 +105246274 Gm41580 MGI:MGI:5624465 +105246275 Gm41581 MGI:MGI:5624466 +105246276 Runx2os3 MGI:MGI:3826565 +105246277 Gm41582 MGI:MGI:5624467 +105246278 B230354K17Rik MGI:MGI:2443272|Ensembl:ENSMUSG00000097119 +105246279 Gm41583 MGI:MGI:5624468 +105246280 Gm41584 MGI:MGI:5624469 +105246281 Gm41585 MGI:MGI:5624470 +105246282 Gm41586 MGI:MGI:5624471 +105246283 Gm41587 MGI:MGI:5624472 +105246284 Gm41588 MGI:MGI:5624473 +105246285 Gm41589 MGI:MGI:5624474 +105246286 Gm41590 MGI:MGI:5624475 +105246287 Gm41591 MGI:MGI:5624476 +105246288 Gm41592 MGI:MGI:5624477 +105246289 Gm41593 MGI:MGI:5624478 +105246290 Gm41594 MGI:MGI:5624479 +105246291 Gm41595 MGI:MGI:5624480 +105246292 Gm41596 MGI:MGI:5624481 +105246293 Gm41597 MGI:MGI:5624482 +105246294 Gm41598 MGI:MGI:5624483 +105246295 Gm41599 MGI:MGI:5624484 +105246296 Gm41600 MGI:MGI:5624485 +105246297 Gm41601 MGI:MGI:5624486 +105246298 Gm41602 MGI:MGI:5624487 +105246299 Gm41603 MGI:MGI:5624488 +105246300 Gm41604 MGI:MGI:5624489 +105246301 Gm41605 MGI:MGI:5624490 +105246302 Gm41606 MGI:MGI:5624491 +105246303 Gm41607 MGI:MGI:5624492 +105246304 Gm41608 MGI:MGI:5624493 +105246305 LOC105246305 - +105246306 Gm41609 MGI:MGI:5624494 +105246307 LOC105246307 - +105246308 Gm41610 MGI:MGI:5624495 +105246309 Gm41611 MGI:MGI:5624496 +105246310 Gm41612 MGI:MGI:5624497 +105246311 Gm41613 MGI:MGI:5624498 +105246312 Gm41614 MGI:MGI:5624499 +105246313 Gm41615 MGI:MGI:5624500 +105246314 Gm41616 MGI:MGI:5624501 +105246315 Gm41617 MGI:MGI:5624502 +105246316 Gm41618 MGI:MGI:5624503 +105246317 Gm41619 MGI:MGI:5624504 +105246318 Gm41620 MGI:MGI:5624505 +105246319 Gm41621 MGI:MGI:5624506 +105246320 Gm26637 MGI:MGI:5477131 +105246321 Gm41622 MGI:MGI:5624507 +105246322 Gm41623 MGI:MGI:5624508 +105246323 Gm41624 MGI:MGI:5624509 +105246324 Gm41625 MGI:MGI:5624510 +105246325 Gm41626 MGI:MGI:5624511 +105246326 Gm41627 MGI:MGI:5624512 +105246327 Gm41628 MGI:MGI:5624513 +105246328 Gm41629 MGI:MGI:5624514 +105246329 Gm41630 MGI:MGI:5624515 +105246330 Gm41631 MGI:MGI:5624516 +105246331 Gm41632 MGI:MGI:5624517 +105246332 Gm41633 MGI:MGI:5624518 +105246333 Gm41634 MGI:MGI:5624519 +105246334 Gm41635 MGI:MGI:5624520 +105246335 Gm41636 MGI:MGI:5624521 +105246336 Gm41637 MGI:MGI:5624522 +105246337 Gm41638 MGI:MGI:5624523 +105246338 Gm41639 MGI:MGI:5624524 +105246339 Gm41640 MGI:MGI:5624525 +105246340 Gm41641 MGI:MGI:5624526 +105246341 Gm41642 MGI:MGI:5624527 +105246342 Gm41643 MGI:MGI:5624528 +105246343 Gm41644 MGI:MGI:5624529 +105246344 Gm41645 MGI:MGI:5624530 +105246346 Gm41646 MGI:MGI:5624531 +105246347 Gm41647 MGI:MGI:5624532 +105246348 Gm41648 MGI:MGI:5624533 +105246349 Gm41649 MGI:MGI:5624534 +105246350 Gm41650 MGI:MGI:5624535 +105246351 Gm41651 MGI:MGI:5624536 +105246352 Gm41652 MGI:MGI:5624537 +105246353 Gm41653 MGI:MGI:5624538 +105246354 Gm41654 MGI:MGI:5624539 +105246355 Gm41655 MGI:MGI:5624540 +105246356 LOC105246356 - +105246357 Gm41656 MGI:MGI:5624541 +105246358 Gm41657 MGI:MGI:5624542 +105246359 Gm41658 MGI:MGI:5624543 +105246360 Gm41659 MGI:MGI:5624544 +105246361 Gm41660 MGI:MGI:5624545 +105246362 Gm41661 MGI:MGI:5624546 +105246363 Gm41662 MGI:MGI:5624547 +105246364 Gm41663 MGI:MGI:5624548 +105246365 Gm41664 MGI:MGI:5624549 +105246366 Mir133a-1hg MGI:MGI:5433911 +105246367 Gm41665 MGI:MGI:5624550 +105246368 Gm41666 MGI:MGI:5624551 +105246369 Gm41667 MGI:MGI:5624552 +105246370 Gm29200 MGI:MGI:5579906 +105246371 Gm41668 MGI:MGI:5624553 +105246373 Gm41669 MGI:MGI:5624554 +105246374 Gm41670 MGI:MGI:5624555 +105246375 Gm41671 MGI:MGI:5624556 +105246376 Gm41672 MGI:MGI:5624557 +105246377 Gm41673 MGI:MGI:5624558 +105246378 Gm41674 MGI:MGI:5624559 +105246379 Gm41675 MGI:MGI:5624560 +105246380 Gm41676 MGI:MGI:5624561 +105246381 Gm41677 MGI:MGI:5624562 +105246383 Gm41678 MGI:MGI:5624563 +105246385 Gm41679 MGI:MGI:5624564 +105246386 Gm41680 MGI:MGI:5624565 +105246387 Gm41681 MGI:MGI:5624566 +105246388 Gm26533 MGI:MGI:5477027 +105246389 Gm26823 MGI:MGI:5477317 +105246390 Gm41682 MGI:MGI:5624567 +105246391 Gm41683 MGI:MGI:5624568 +105246392 Gm41684 MGI:MGI:5624569 +105246393 Gm41685 MGI:MGI:5624570 +105246394 Gm41686 MGI:MGI:5624571 +105246395 Gm41687 MGI:MGI:5624572 +105246396 Gm41688 MGI:MGI:5624573 +105246397 Gm41689 MGI:MGI:5624574 +105246398 Gm41690 MGI:MGI:5624575 +105246399 Gm41691 MGI:MGI:5624576 +105246400 Gm41692 MGI:MGI:5624577 +105246401 Gm41693 MGI:MGI:5624578 +105246402 Gm41694 MGI:MGI:5624579 +105246403 Gm41695 MGI:MGI:5624580 +105246404 Gm41696 MGI:MGI:5624581 +105246405 Gm41697 MGI:MGI:5624582 +105246406 Gm41698 MGI:MGI:5624583 +105246407 Gm41699 MGI:MGI:5624584 +105246408 Gm41700 MGI:MGI:5624585 +105246409 LOC105246409 - +105246410 Gm41701 MGI:MGI:5624586 +105246412 Gm41702 MGI:MGI:5624587 +105246413 Gm41703 MGI:MGI:5624588 +105246414 Gm41704 MGI:MGI:5624589 +105246415 Gm41705 MGI:MGI:5624590 +105246416 Gm41706 MGI:MGI:5624591 +105246417 Gm41707 MGI:MGI:5624592 +105246418 Gm41708 MGI:MGI:5624593 +105246419 Gm41709 MGI:MGI:5624594 +105246420 Gm41710 MGI:MGI:5624595 +105246421 Gm41711 MGI:MGI:5624596 +105246422 Gm41712 MGI:MGI:5624597 +105246423 Gm41713 MGI:MGI:5624598 +105246424 Gm41714 MGI:MGI:5624599 +105246425 Gm41715 MGI:MGI:5624600 +105246426 Gm41716 MGI:MGI:5624601 +105246427 Gm41717 MGI:MGI:5624602 +105246428 Gm41718 MGI:MGI:5624603 +105246429 Gm41719 MGI:MGI:5624604 +105246430 Gm41720 MGI:MGI:5624605 +105246431 Gm41721 MGI:MGI:5624606 +105246432 Gm41722 MGI:MGI:5624607 +105246433 Gm41723 MGI:MGI:5624608 +105246434 Gm41724 MGI:MGI:5624609 +105246435 Gm41725 MGI:MGI:5624610 +105246436 Gm41726 MGI:MGI:5624611 +105246437 Gm41727 MGI:MGI:5624612 +105246438 Gm41728 MGI:MGI:5624613 +105246439 Gm41729 MGI:MGI:5624614 +105246440 Gm41730 MGI:MGI:5624615 +105246441 LOC105246441 - +105246442 Gm41731 MGI:MGI:5624616 +105246443 Gm41732 MGI:MGI:5624617 +105246444 Gm41733 MGI:MGI:5624618 +105246445 Gm41734 MGI:MGI:5624619 +105246446 Gm41735 MGI:MGI:5624620 +105246447 Gm41736 MGI:MGI:5624621 +105246448 Gm41737 MGI:MGI:5624622 +105246449 Gm41738 MGI:MGI:5624623 +105246450 Gm41739 MGI:MGI:5624624 +105246451 Gm41740 MGI:MGI:5624625 +105246452 Gm15345 MGI:MGI:3705179 +105246453 Gm26507 MGI:MGI:5477001 +105246454 Gm41741 MGI:MGI:5624626 +105246455 Gm41742 MGI:MGI:5624627 +105246456 Gm41743 MGI:MGI:5624628 +105246458 Gm41744 MGI:MGI:5624629 +105246459 Gm41745 MGI:MGI:5624630 +105246460 Gm41746 MGI:MGI:5624631 +105246461 Gm41747 MGI:MGI:5624632 +105246462 Gm41748 MGI:MGI:5624633 +105246463 Gm41749 MGI:MGI:5624634 +105246464 Gm41750 MGI:MGI:5624635 +105246465 Gm41751 MGI:MGI:5624636 +105246466 Gm41752 MGI:MGI:5624637 +105246467 Gm26972 MGI:MGI:5504087 +105246468 Gm41753 MGI:MGI:5624638 +105246469 Gm41754 MGI:MGI:5624639 +105246470 Gm41755 MGI:MGI:5624640 +105246471 Gm41756 MGI:MGI:5624641 +105246472 Gm41757 MGI:MGI:5624642 +105246473 Gm41758 MGI:MGI:5624643 +105246474 Gm41759 MGI:MGI:5624644 +105246475 Gm41760 MGI:MGI:5624645 +105246476 Gm41761 MGI:MGI:5624646 +105246477 Gm41762 MGI:MGI:5624647 +105246478 Gm41763 MGI:MGI:5624648 +105246479 Gm41764 MGI:MGI:5624649 +105246480 Gm41765 MGI:MGI:5624650 +105246481 Gm41766 MGI:MGI:5624651 +105246482 Gm41767 MGI:MGI:5624652 +105246483 Gm41768 MGI:MGI:5624653 +105246484 Gm41769 MGI:MGI:5624654 +105246485 Gm41770 MGI:MGI:5624655 +105246486 Gm41771 MGI:MGI:5624656 +105246487 Gm41772 MGI:MGI:5624657 +105246488 Gm41773 MGI:MGI:5624658 +105246489 Gm41774 MGI:MGI:5624659 +105246490 Gm41775 MGI:MGI:5624660 +105246491 Gm41776 MGI:MGI:5624661 +105246492 Gm41777 MGI:MGI:5624662 +105246493 Gm41778 MGI:MGI:5624663 +105246494 Gm41779 MGI:MGI:5624664 +105246495 Gm41780 MGI:MGI:5624665 +105246496 LOC105246496 - +105246497 Gm41781 MGI:MGI:5624666 +105246498 Gm41782 MGI:MGI:5624667 +105246499 Gm41783 MGI:MGI:5624668 +105246500 Gm41784 MGI:MGI:5624669 +105246501 LOC105246501 - +105246503 Gm41785 MGI:MGI:5624670 +105246504 Gm41786 MGI:MGI:5624671 +105246505 Gm41787 MGI:MGI:5624672 +105246506 LOC105246506 - +105246507 Gm41788 MGI:MGI:5624673 +105246508 Gm41789 MGI:MGI:5624674 +105246509 Gm41790 MGI:MGI:5624675 +105246510 Gm41791 MGI:MGI:5624676 +105246511 Gm41792 MGI:MGI:5624677 +105246512 Gm41793 MGI:MGI:5624678 +105246513 Gm41794 MGI:MGI:5624679 +105246514 Gm41795 MGI:MGI:5624680 +105246515 Gm41796 MGI:MGI:5624681 +105246516 Gm41797 MGI:MGI:5624682 +105246517 Gm41798 MGI:MGI:5624683 +105246519 Gm16146 MGI:MGI:3801801 +105246520 Gm41799 MGI:MGI:5624684 +105246521 Gm41800 MGI:MGI:5624685 +105246522 Gm26977 MGI:MGI:5504092 +105246526 Gm41801 MGI:MGI:5624686 +105246527 Gm41802 MGI:MGI:5624687 +105246528 Gm41803 MGI:MGI:5624688 +105246529 Gm41804 MGI:MGI:5624689 +105246530 Gm41805 MGI:MGI:5624690 +105246531 LOC105246531 - +105246532 Gm41806 MGI:MGI:5624691 +105246533 Gm41807 MGI:MGI:5624692 +105246534 Gm41808 MGI:MGI:5624693 +105246535 Gm41809 MGI:MGI:5624694 +105246536 Gm41810 MGI:MGI:5624695 +105246537 Gm41811 MGI:MGI:5624696 +105246538 Gm41812 MGI:MGI:5624697 +105246539 Gm41813 MGI:MGI:5624698 +105246540 Gm41814 MGI:MGI:5624699 +105246541 Gm41815 MGI:MGI:5624700 +105246542 Gm41816 MGI:MGI:5624701 +105246543 Gm41817 MGI:MGI:5624702 +105246544 Gm41818 MGI:MGI:5624703 +105246545 Gm41819 MGI:MGI:5624704 +105246546 Gm41820 MGI:MGI:5624705 +105246547 Gm41821 MGI:MGI:5624706 +105246548 Gm41822 MGI:MGI:5624707 +105246549 Gm41823 MGI:MGI:5624708 +105246550 Gm41824 MGI:MGI:5624709 +105246551 Gm41825 MGI:MGI:5624710 +105246552 Gm41826 MGI:MGI:5624711 +105246553 Gm41827 MGI:MGI:5624712 +105246554 Gm41828 MGI:MGI:5624713 +105246555 Gm41829 MGI:MGI:5624714 +105246556 Gm41830 MGI:MGI:5624715 +105246557 Gm41831 MGI:MGI:5624716 +105246558 Gm41832 MGI:MGI:5624717 +105246559 Gm41833 MGI:MGI:5624718 +105246560 Gm41834 MGI:MGI:5624719 +105246561 Gm41835 MGI:MGI:5624720 +105246562 Gm41836 MGI:MGI:5624721 +105246564 Gm41837 MGI:MGI:5624722 +105246565 Gm41838 MGI:MGI:5624723 +105246566 Gm41839 MGI:MGI:5624724 +105246567 Gm41840 MGI:MGI:5624725 +105246568 Gm41841 MGI:MGI:5624726 +105246569 Gm41842 MGI:MGI:5624727 +105246570 Gm41843 MGI:MGI:5624728 +105246571 LOC105246571 - +105246572 Gm41844 MGI:MGI:5624729 +105246573 Gm41845 MGI:MGI:5624730 +105246574 Gm41846 MGI:MGI:5624731 +105246575 LOC105246575 - +105246576 Gm41847 MGI:MGI:5624732 +105246577 Gm41848 MGI:MGI:5624733 +105246578 Gm41849 MGI:MGI:5624734 +105246579 Gm41850 MGI:MGI:5624735 +105246580 Gm41851 MGI:MGI:5624736 +105246581 Gm41852 MGI:MGI:5624737 +105246582 Gm41853 MGI:MGI:5624738 +105246583 Gm41854 MGI:MGI:5624739 +105246584 Gm41855 MGI:MGI:5624740 +105246585 Gm41856 MGI:MGI:5624741 +105246586 LOC105246586 - +105246587 Gm41857 MGI:MGI:5624742 +105246588 Gm41858 MGI:MGI:5624743 +105246589 Gm41859 MGI:MGI:5624744 +105246590 Gm41860 MGI:MGI:5624745 +105246591 Gm41861 MGI:MGI:5624746 +105246592 Gm41862 MGI:MGI:5624747 +105246593 Gm41863 MGI:MGI:5624748 +105246594 Gm41864 MGI:MGI:5624749 +105246595 Gm41865 MGI:MGI:5624750 +105246596 Gm41866 MGI:MGI:5624751 +105246597 Gm41867 MGI:MGI:5624752 +105246598 Gm41868 MGI:MGI:5624753 +105246599 Gm41869 MGI:MGI:5624754 +105246600 Gm41870 MGI:MGI:5624755 +105246601 LOC105246601 - +105246602 Gm41871 MGI:MGI:5624756 +105246603 Gm41872 MGI:MGI:5624757 +105246604 Gm41873 MGI:MGI:5624758 +105246606 Gm41874 MGI:MGI:5624759 +105246607 Gm16277 MGI:MGI:3826543 +105246608 Gm41875 MGI:MGI:5624760 +105246609 Gm41876 MGI:MGI:5624761 +105246610 Gm41877 MGI:MGI:5624762 +105246611 Gm41878 MGI:MGI:5624763 +105246612 Gm41879 MGI:MGI:5624764 +105246613 Gm41880 MGI:MGI:5624765 +105246614 Gm41881 MGI:MGI:5624766 +105246615 Gm41882 MGI:MGI:5624767 +105246616 Gm41883 MGI:MGI:5624768 +105246617 Gm41884 MGI:MGI:5624769 +105246618 Gm41885 MGI:MGI:5624770 +105246619 Scgb2a2 - +105246620 Gm41886 MGI:MGI:5624771 +105246622 Gm41887 MGI:MGI:5624772 +105246623 Gm41888 MGI:MGI:5624773 +105246624 Gm41889 MGI:MGI:5624774 +105246625 Gm41890 MGI:MGI:5624775 +105246626 Gm41891 MGI:MGI:5624776 +105246627 Gm41892 MGI:MGI:5624777 +105246628 Gm41893 MGI:MGI:5624778 +105246629 Gm41894 MGI:MGI:5624779 +105246632 LOC105246632 - +105246633 Gm41895 MGI:MGI:5624780 +105246634 Gm41896 MGI:MGI:5624781 +105246635 Gm41897 MGI:MGI:5624782 +105246636 LOC105246636 - +105246637 Gm41898 MGI:MGI:5624783 +105246638 LOC105246638 - +105246639 LOC105246639 - +105246640 Gm41899 MGI:MGI:5624784 +105246641 Gm41900 MGI:MGI:5624785 +105246642 Gm41901 MGI:MGI:5624786 +105246643 LOC105246643 - +105246644 Gm41902 MGI:MGI:5624787 +105246645 Gm41903 MGI:MGI:5624788 +105246646 Gm41904 MGI:MGI:5624789 +105246647 Gm41905 MGI:MGI:5624790 +105246648 Gm41906 MGI:MGI:5624791 +105246649 Gm41907 MGI:MGI:5624792 +105246650 Gm41908 MGI:MGI:5624793 +105246651 Gm41909 MGI:MGI:5624794 +105246652 Gm41910 MGI:MGI:5624795 +105246653 Gm41911 MGI:MGI:5624796 +105246654 Gm41912 MGI:MGI:5624797 +105246655 Gm41913 MGI:MGI:5624798 +105246656 Gm28499 MGI:MGI:5579205 +105246657 Gm41914 MGI:MGI:5624799 +105246658 Gm41915 MGI:MGI:5624800 +105246659 Gm41916 MGI:MGI:5624801 +105246660 Gm28722 MGI:MGI:5579428 +105246662 Gm41917 MGI:MGI:5624802 +105246663 Gm41918 MGI:MGI:5624803 +105246664 Gm41919 MGI:MGI:5624804 +105246665 Gm28535 MGI:MGI:5579241|Ensembl:ENSMUSG00000101172 +105246666 Gm41920 MGI:MGI:5624805 +105246667 Gm29601 MGI:MGI:5580307 +105246668 LOC105246668 - +105246669 Gm41921 MGI:MGI:5624806 +105246670 Gm41922 MGI:MGI:5624807 +105246671 Gm41923 MGI:MGI:5624808 +105246672 Gm41924 MGI:MGI:5624809 +105246673 Gm41925 MGI:MGI:5624810 +105246674 Gm28403 MGI:MGI:5579109 +105246675 Gm41926 MGI:MGI:5624811 +105246676 Gm41927 MGI:MGI:5624812 +105246677 Gm26509 MGI:MGI:5477003 +105246678 Gm41928 MGI:MGI:5624813 +105246679 Gm37053 MGI:MGI:5610281 +105246680 Gm41929 MGI:MGI:5624814 +105246681 Gm28282 MGI:MGI:5578988 +105246682 Gm41930 MGI:MGI:5624815 +105246683 Gm41931 MGI:MGI:5624816 +105246684 Gm41932 MGI:MGI:5624817 +105246685 Gm41933 MGI:MGI:5624818 +105246686 Gm41934 MGI:MGI:5624819 +105246687 Gm41935 MGI:MGI:5624820 +105246688 Gm41936 MGI:MGI:5624821 +105246689 Gm41937 MGI:MGI:5624822 +105246690 Gm41938 MGI:MGI:5624823 +105246691 Gm41939 MGI:MGI:5624824 +105246692 Gm29345 MGI:MGI:5580051 +105246693 Gm41940 MGI:MGI:5624825 +105246694 Gm41941 MGI:MGI:5624826 +105246695 Gm41942 MGI:MGI:5624827 +105246696 Gm41943 MGI:MGI:5624828 +105246697 Gm41944 MGI:MGI:5624829 +105246698 Gm41945 MGI:MGI:5624830 +105246699 Gm41946 MGI:MGI:5624831 +105246700 Gm41947 MGI:MGI:5624832 +105246701 Gm41948 MGI:MGI:5624833 +105246702 Gm41949 MGI:MGI:5624834 +105246703 Gm41950 MGI:MGI:5624835 +105246704 Gm41951 MGI:MGI:5624836 +105246705 Gm15675 MGI:MGI:3783117 +105246706 Gm41952 MGI:MGI:5624837 +105246707 LOC105246707 - +105246708 Gm41953 MGI:MGI:5624838 +105246709 Gm41954 MGI:MGI:5624839 +105246710 LOC105246710 - +105246711 Gm41955 MGI:MGI:5624840 +105246712 Gm41956 MGI:MGI:5624841 +105246713 Gm41957 MGI:MGI:5624842 +105246714 Gm41958 MGI:MGI:5624843 +105246715 Gm41959 MGI:MGI:5624844 +105246716 Gm28500 MGI:MGI:5579206 +105246717 Gm41960 MGI:MGI:5624845 +105246718 Gm41961 MGI:MGI:5624846 +105246719 Gm41962 MGI:MGI:5624847 +105246720 Gm41963 MGI:MGI:5624848 +105246721 Gm41964 MGI:MGI:5624849 +105246722 Gm41965 MGI:MGI:5624850 +105246723 Gm41966 MGI:MGI:5624851 +105246724 Gm29398 MGI:MGI:5580104 +105246725 Gm41967 MGI:MGI:5624852 +105246726 Gm41968 MGI:MGI:5624853 +105246727 Gm41969 MGI:MGI:5624854 +105246728 Gm41970 MGI:MGI:5624855 +105246729 Gm41971 MGI:MGI:5624856 +105246730 Gm41972 MGI:MGI:5624857 +105246731 Gm41973 MGI:MGI:5624858 +105246732 Gm41974 MGI:MGI:5624859 +105246733 Gm41975 MGI:MGI:5624860 +105246734 Gm41976 MGI:MGI:5624861 +105246735 Gm41977 MGI:MGI:5624862 +105246736 Gm41978 MGI:MGI:5624863 +105246737 Gm41979 MGI:MGI:5624864 +105246738 Gm41980 MGI:MGI:5624865 +105246739 Gm41981 MGI:MGI:5624866 +105246740 Gm41982 MGI:MGI:5624867 +105246741 Gm41983 MGI:MGI:5624868 +105246742 Gm41984 MGI:MGI:5624869 +105246743 Gm41985 MGI:MGI:5624870 +105246744 Gm41986 MGI:MGI:5624871 +105246745 Gm41987 MGI:MGI:5624872 +105246746 Gm41988 MGI:MGI:5624873 +105246747 Gm41989 MGI:MGI:5624874 +105246748 Gm41990 MGI:MGI:5624875 +105246749 Gm41991 MGI:MGI:5624876 +105246750 Gm41992 MGI:MGI:5624877 +105246751 Gm41993 MGI:MGI:5624878 +105246752 Gm41994 MGI:MGI:5624879 +105246753 Gm41995 MGI:MGI:5624880 +105246754 Gm41996 MGI:MGI:5624881 +105246755 Gm41997 MGI:MGI:5624882 +105246756 Gm41998 MGI:MGI:5624883 +105246757 Gm41999 MGI:MGI:5624884 +105246758 Gm42000 MGI:MGI:5624885 +105246759 Gm42001 MGI:MGI:5624886 +105246760 Gm42002 MGI:MGI:5624887 +105246761 Gm42003 MGI:MGI:5624888 +105246762 Gm42004 MGI:MGI:5624889 +105246763 Gm42005 MGI:MGI:5624890 +105246765 LOC105246765 - +105246766 Gm13822 MGI:MGI:3650351 +105246767 Gm42006 MGI:MGI:5624891 +105246768 Gm42007 MGI:MGI:5624892 +105246769 Gm42008 MGI:MGI:5624893 +105246770 Gm42009 MGI:MGI:5624894 +105246771 Gm42010 MGI:MGI:5624895 +105246772 Gm42011 MGI:MGI:5624896 +105246773 Gm42012 MGI:MGI:5624897 +105246774 Gm42013 MGI:MGI:5624898 +105246775 Gm42014 MGI:MGI:5624899 +105246776 Gm42015 MGI:MGI:5624900 +105246777 Gm42016 MGI:MGI:5624901 +105246778 Gm16064 MGI:MGI:3801956 +105246779 Gm42017 MGI:MGI:5624902 +105246780 Gm42018 MGI:MGI:5624903 +105246781 Gm42019 MGI:MGI:5624904 +105246782 Gm42020 MGI:MGI:5624905 +105246783 Gm42021 MGI:MGI:5624906 +105246784 Gm42022 MGI:MGI:5624907 +105246785 Gm42023 MGI:MGI:5624908 +105246786 Gm42024 MGI:MGI:5624909 +105246787 Gm42025 MGI:MGI:5624910 +105246788 Gm34166 MGI:MGI:5593325 +105246801 Gm42026 MGI:MGI:5624911 +105246802 Gm42027 MGI:MGI:5624912 +105246803 Gm42028 MGI:MGI:5624913 +105246804 LOC105246804 - +105246805 Gm42029 MGI:MGI:5624914 +105246806 Gm42030 MGI:MGI:5624915 +105246807 Gm42031 MGI:MGI:5624916 +105246808 Gm42032 MGI:MGI:5624917 +105246809 Gm42033 MGI:MGI:5624918 +105246810 Gm42034 MGI:MGI:5624919 +105246811 Gm42035 MGI:MGI:5624920 +105246812 Gm42036 MGI:MGI:5624921 +105246813 Gm42037 MGI:MGI:5624922 +105246814 Gm42038 MGI:MGI:5624923 +105246815 Gm42039 MGI:MGI:5624924 +105246816 Gm42040 MGI:MGI:5624925 +105246817 Gm42041 MGI:MGI:5624926 +105246818 Gm42042 MGI:MGI:5624927 +105246819 Gm42043 MGI:MGI:5624928 +105246820 Gm42044 MGI:MGI:5624929 +105246821 Gm42045 MGI:MGI:5624930 +105246822 Gm42046 MGI:MGI:5624931 +105246823 Gm42047 MGI:MGI:5624932 +105246824 Gm42048 MGI:MGI:5624933 +105246825 Gm42049 MGI:MGI:5624934 +105246826 Gm42050 MGI:MGI:5624935 +105246827 Gm42051 MGI:MGI:5624936 +105246828 Gm42052 MGI:MGI:5624937 +105246829 Gm42053 MGI:MGI:5624938 +105246830 Gm42054 MGI:MGI:5624939 +105246831 Gm42055 MGI:MGI:5624940 +105246832 Gm42056 MGI:MGI:5624941 +105246833 LOC105246833 - +105246835 Gm42057 MGI:MGI:5624942 +105246836 Gm42058 MGI:MGI:5624943 +105246837 Gm42059 MGI:MGI:5624944 +105246838 Gm42060 MGI:MGI:5624945 +105246839 Gm42061 MGI:MGI:5624946 +105246840 Gm42062 MGI:MGI:5624947 +105246841 Gm42063 MGI:MGI:5624948 +105246843 Gm42064 MGI:MGI:5624949 +105246844 Gm42065 MGI:MGI:5624950 +105246845 Gm42066 MGI:MGI:5624951 +105246846 Gm42067 MGI:MGI:5624952|Ensembl:ENSMUSG00000110156 +105246847 LOC105246847 Ensembl:ENSMUSG00000085196 +105246848 Gm14965 MGI:MGI:3705214|Ensembl:ENSMUSG00000084876 +105246849 Gm42068 MGI:MGI:5624953 +105246851 LOC105246851 - +105246858 Gm42069 MGI:MGI:5624954 +105246859 Gm42070 MGI:MGI:5624955 +105246860 Gm42071 MGI:MGI:5624956 +105246861 Gm12126 MGI:MGI:3652211 +105246862 Gm42072 MGI:MGI:5624957 +105246865 Gm42073 MGI:MGI:5624958 +105246866 Gm42074 MGI:MGI:5624959 +105246867 Gm42075 MGI:MGI:5624960 +105246868 Gm12206 MGI:MGI:3650472 +105246869 Gm42076 MGI:MGI:5624961 +105246870 Gm12257 MGI:MGI:3651532 +105246871 Gm42077 MGI:MGI:5624962 +105246872 Gm42078 MGI:MGI:5624963 +105246873 Gm42079 MGI:MGI:5624964 +105246874 Gm42080 MGI:MGI:5624965 +105246875 Gm42081 MGI:MGI:5624966 +105246876 Gm42082 MGI:MGI:5624967 +105246877 Gm42083 MGI:MGI:5624968 +105246878 Gm42084 MGI:MGI:5624969 +105246880 Gm42085 MGI:MGI:5624970 +105246881 Gm42086 MGI:MGI:5624971 +105246882 Gm42087 MGI:MGI:5624972 +105246883 Gm42088 MGI:MGI:5624973 +105246884 Gm42089 MGI:MGI:5624974 +105246886 LOC105246886 - +105246887 Gm42090 MGI:MGI:5624975 +105246888 Gm42091 MGI:MGI:5624976 +105246889 Gm42092 MGI:MGI:5624977 +105246890 Gm42093 MGI:MGI:5624978 +105246891 Gm42094 MGI:MGI:5624979 +105246892 Gm42095 MGI:MGI:5624980 +105246893 Gm42096 MGI:MGI:5624981 +105246894 Gm11753 MGI:MGI:3651699 +105246895 LOC105246895 - +105246896 Gm42097 MGI:MGI:5624982 +105246897 Gm42098 MGI:MGI:5624983 +105246898 Gm42099 MGI:MGI:5624984 +105246899 Gm42100 MGI:MGI:5624985 +105246900 LOC105246900 - +105246901 Gm42101 MGI:MGI:5624986 +105246904 Gm42102 MGI:MGI:5624987 +105246905 Gm42103 MGI:MGI:5624988 +105246906 Gm42104 MGI:MGI:5624989 +105246907 Gm15831 MGI:MGI:3801916 +105246908 Gm42105 MGI:MGI:5624990 +105246909 Gm42106 MGI:MGI:5624991 +105246910 Gm42107 MGI:MGI:5624992 +105246911 Gm42108 MGI:MGI:5624993 +105246912 Gm42109 MGI:MGI:5624994 +105246913 Gm42110 MGI:MGI:5624995 +105246914 LOC105246914 - +105246915 Gm42111 MGI:MGI:5624996 +105246916 Gm42112 MGI:MGI:5624997 +105246917 Gm42113 MGI:MGI:5624998 +105246918 Gm42114 MGI:MGI:5624999 +105246919 Gm42115 MGI:MGI:5625000 +105246921 Gm42116 MGI:MGI:5625001 +105246922 Gm42117 MGI:MGI:5625002 +105246923 Gm42118 MGI:MGI:5625003 +105246924 Gm42119 MGI:MGI:5625004 +105246925 Gm42120 MGI:MGI:5625005 +105246926 Gm42121 MGI:MGI:5625006 +105246927 Gm42122 MGI:MGI:5625007 +105246928 Gm42123 MGI:MGI:5625008 +105246929 Gm42124 MGI:MGI:5625009 +105246930 Gm16227 MGI:MGI:3801791|Ensembl:ENSMUSG00000090006 +105246931 Gm42125 MGI:MGI:5625010 +105246932 Gm42126 MGI:MGI:5625011 +105246933 Gm42127 MGI:MGI:5625012 +105246934 Gm42128 MGI:MGI:5625013 +105246935 Gm42129 MGI:MGI:5625014 +105246936 Gm42130 MGI:MGI:5625015 +105246937 Gm42131 MGI:MGI:5625016 +105246938 Gm42132 MGI:MGI:5625017 +105246939 Gm42133 MGI:MGI:5625018 +105246940 Gm42134 MGI:MGI:5625019 +105246941 Gm42135 MGI:MGI:5625020 +105246942 Gm42136 MGI:MGI:5625021 +105246943 Gm42137 MGI:MGI:5625022 +105246944 Gm42138 MGI:MGI:5625023 +105246945 Gm42139 MGI:MGI:5625024 +105246946 Gm26703 MGI:MGI:5477197 +105246947 Gm42140 MGI:MGI:5625025 +105246948 Gm42141 MGI:MGI:5625026 +105246949 Gm42142 MGI:MGI:5625027 +105246950 Gm42143 MGI:MGI:5625028 +105246951 Gm42144 MGI:MGI:5625029 +105246952 Gm42145 MGI:MGI:5625030 +105246953 Gm42146 MGI:MGI:5625031 +105246954 Gm42147 MGI:MGI:5625032 +105246955 Gm42148 MGI:MGI:5625033 +105246956 Gm42149 MGI:MGI:5625034 +105246957 Gm42150 MGI:MGI:5625035 +105246959 Gm42151 MGI:MGI:5625036 +105246960 Gm42152 MGI:MGI:5625037 +105246961 LOC105246961 - +105246962 LOC105246962 - +105246963 Gm42153 MGI:MGI:5625038 +105246964 Gm42154 MGI:MGI:5625039 +105246965 Gm42155 MGI:MGI:5625040 +105246966 Gm42156 MGI:MGI:5625041 +105246967 Gm42157 MGI:MGI:5625042 +105246968 Gm20636 MGI:MGI:5313083 +105246969 Gm42158 MGI:MGI:5625043 +105246970 Gm42159 MGI:MGI:5625044 +105246971 Gm42160 MGI:MGI:5625045 +105246972 Gm42161 MGI:MGI:5625046 +105246973 LOC105246973 - +105246974 Gm42162 MGI:MGI:5625047 +105246975 Gm42163 MGI:MGI:5625048 +105246976 Gm42164 MGI:MGI:5625049 +105246977 Gm42165 MGI:MGI:5625050 +105246978 Gm42166 MGI:MGI:5625051 +105246979 Gm42167 MGI:MGI:5625052 +105246980 Gm42168 MGI:MGI:5625053 +105246981 Gm42169 MGI:MGI:5625054 +105246982 Gm42170 MGI:MGI:5625055 +105246983 Gm42171 MGI:MGI:5625056 +105246984 Gm42172 MGI:MGI:5625057 +105246985 Gm42173 MGI:MGI:5625058 +105246986 Gm42174 MGI:MGI:5625059 +105246987 Gm42175 MGI:MGI:5625060 +105246988 Gm42176 MGI:MGI:5625061 +105246989 Gm42177 MGI:MGI:5625062 +105246990 Gm42178 MGI:MGI:5625063 +105246991 Gm42179 MGI:MGI:5625064 +105246992 Gm42180 MGI:MGI:5625065 +105246993 Gm42181 MGI:MGI:5625066 +105246994 Gm42182 MGI:MGI:5625067 +105246995 Gm42183 MGI:MGI:5625068 +105246998 Gm42184 MGI:MGI:5625069 +105246999 Gm42185 MGI:MGI:5625070 +105247001 Gm42186 MGI:MGI:5625071 +105247002 Gm42187 MGI:MGI:5625072 +105247004 Gm42188 MGI:MGI:5625073 +105247005 Gm42189 MGI:MGI:5625074 +105247006 Gm42190 MGI:MGI:5625075 +105247007 Gm42191 MGI:MGI:5625076 +105247008 Gm42192 MGI:MGI:5625077 +105247009 Gm42193 MGI:MGI:5625078 +105247010 Gm42194 MGI:MGI:5625079 +105247011 Gm42195 MGI:MGI:5625080 +105247012 Gm42196 MGI:MGI:5625081 +105247013 Gm42197 MGI:MGI:5625082 +105247014 Mecomos MGI:MGI:4439646 +105247015 Gm42198 MGI:MGI:5625083 +105247016 Gm42199 MGI:MGI:5625084 +105247017 Gm42200 MGI:MGI:5625085 +105247019 Gm42201 MGI:MGI:5625086 +105247020 Gm42202 MGI:MGI:5625087 +105247021 Gm42203 MGI:MGI:5625088 +105247022 Gm42204 MGI:MGI:5625089 +105247023 Gm42205 MGI:MGI:5625090 +105247024 Gm42206 MGI:MGI:5625091 +105247025 Gm42207 MGI:MGI:5625092 +105247026 Gm42208 MGI:MGI:5625093 +105247027 Gm42209 MGI:MGI:5625094 +105247028 Gm42210 MGI:MGI:5625095 +105247029 Gm42211 MGI:MGI:5625096 +105247030 Gm42212 MGI:MGI:5625097 +105247031 Gm42213 MGI:MGI:5625098 +105247032 Gm42214 MGI:MGI:5625099 +105247033 Gm42215 MGI:MGI:5625100 +105247034 Gm42216 MGI:MGI:5625101 +105247035 Gm42217 MGI:MGI:5625102 +105247037 Gm42218 MGI:MGI:5625103 +105247041 Gm42219 MGI:MGI:5625104 +105247042 Gm42220 MGI:MGI:5625105 +105247043 Gm42221 MGI:MGI:5625106 +105247044 Gm42222 MGI:MGI:5625107 +105247045 LOC105247045 - +105247046 Gm42223 MGI:MGI:5625108 +105247047 Gm42224 MGI:MGI:5625109 +105247048 LOC105247048 - +105247049 Gm42225 MGI:MGI:5625110 +105247050 Gm42226 MGI:MGI:5625111 +105247051 Gm42227 MGI:MGI:5625112 +105247052 Gm42228 MGI:MGI:5625113 +105247053 Gm42229 MGI:MGI:5625114 +105247054 Gm15589 MGI:MGI:3783037 +105247055 Gm42230 MGI:MGI:5625115 +105247056 Gm42231 MGI:MGI:5625116 +105247057 Gm42232 MGI:MGI:5625117 +105247058 Gm42233 MGI:MGI:5625118 +105247059 Gm42234 MGI:MGI:5625119 +105247060 Gm42235 MGI:MGI:5625120 +105247061 Gm42236 MGI:MGI:5625121 +105247062 Gm42237 MGI:MGI:5625122 +105247063 Gm42238 MGI:MGI:5625123 +105247064 Gm42239 MGI:MGI:5625124 +105247065 Gm16058 MGI:MGI:3802026 +105247066 Gm42240 MGI:MGI:5625125 +105247067 LOC105247067 - +105247068 Gm42241 MGI:MGI:5625126 +105247069 Gm42242 MGI:MGI:5625127 +105247070 Gm42243 MGI:MGI:5625128 +105247071 Gm42244 MGI:MGI:5625129 +105247072 Gm42245 MGI:MGI:5625130 +105247073 Gm42246 MGI:MGI:5625131 +105247075 LOC105247075 - +105247076 LOC105247076 - +105247078 Gm42247 MGI:MGI:5625132 +105247082 Gm15281 MGI:MGI:3826553 +105247085 Gm42248 MGI:MGI:5625133 +105247087 Gm42249 MGI:MGI:5625134 +105247090 Gm42250 MGI:MGI:5625135 +105247091 Gm42251 MGI:MGI:5625136 +105247092 Gm42252 MGI:MGI:5625137 +105247093 Gm42253 MGI:MGI:5625138 +105247094 Gm42254 MGI:MGI:5625139 +105247095 Gm26663 MGI:MGI:5477157 +105247096 Gm42255 MGI:MGI:5625140 +105247097 Gm42256 MGI:MGI:5625141 +105247098 Gm42257 MGI:MGI:5625142 +105247099 Gm42258 MGI:MGI:5625143 +105247100 Gm42259 MGI:MGI:5625144 +105247101 LOC105247101 - +105247102 Gm42260 MGI:MGI:5625145 +105247103 Gm42261 MGI:MGI:5625146 +105247104 Gm42262 MGI:MGI:5625147 +105247105 Gm42263 MGI:MGI:5625148 +105247106 Gm42264 MGI:MGI:5625149 +105247107 Gm42265 MGI:MGI:5625150 +105247108 Gm42266 MGI:MGI:5625151 +105247109 Gm42267 MGI:MGI:5625152 +105247110 Gm42268 MGI:MGI:5625153 +105247111 Gm42269 MGI:MGI:5625154 +105247112 Gm42270 MGI:MGI:5625155 +105247113 Gm42271 MGI:MGI:5625156 +105247114 Gm42272 MGI:MGI:5625157 +105247115 Gm42273 MGI:MGI:5625158 +105247116 Gm42274 MGI:MGI:5625159 +105247117 Gm42275 MGI:MGI:5625160 +105247118 Gm42276 MGI:MGI:5625161 +105247119 Gm42277 MGI:MGI:5625162 +105247120 Gm26881 MGI:MGI:5477375 +105247121 Gm42278 MGI:MGI:5625163 +105247122 Gm42279 MGI:MGI:5625164 +105247123 Gm42280 MGI:MGI:5625165 +105247124 Gm42281 MGI:MGI:5625166 +105247125 LOC105247125 - +105247126 Gm16731 MGI:MGI:4439655 +105247127 Gm42282 MGI:MGI:5625167 +105247128 Gm42283 MGI:MGI:5625168 +105247129 Gm42284 MGI:MGI:5625169 +105247130 Gm42285 MGI:MGI:5625170 +105247131 Gm42286 MGI:MGI:5625171 +105247132 Gm42287 MGI:MGI:5625172 +105247133 Gm42288 MGI:MGI:5625173 +105247134 Gm42289 MGI:MGI:5625174 +105247135 Gm12514 MGI:MGI:3651364 +105247136 Gm42290 MGI:MGI:5625175 +105247137 Gm42291 MGI:MGI:5625176 +105247138 Gm42292 MGI:MGI:5625177 +105247139 Gm42293 MGI:MGI:5625178 +105247140 Gm11210 MGI:MGI:3650633 +105247141 Gm42294 MGI:MGI:5625179 +105247142 Gm42295 MGI:MGI:5625180 +105247144 Gm42296 MGI:MGI:5625181 +105247145 Gm42297 MGI:MGI:5625182 +105247146 Gm42298 MGI:MGI:5625183 +105247147 Gm42299 MGI:MGI:5625184 +105247148 Gm42300 MGI:MGI:5625185 +105247149 Gm42301 MGI:MGI:5625186 +105247150 Gm42302 MGI:MGI:5625187 +105247151 Gm42303 MGI:MGI:5625188 +105247152 Gm42304 MGI:MGI:5625189 +105247153 Gm11267 MGI:MGI:3649847 +105247154 Gm42305 MGI:MGI:5625190 +105247155 Gm42306 MGI:MGI:5625191 +105247156 Gm42307 MGI:MGI:5625192 +105247157 Gm42308 MGI:MGI:5625193 +105247158 Gm42309 MGI:MGI:5625194 +105247159 Gm11415 MGI:MGI:3650502 +105247160 Gm42310 MGI:MGI:5625195 +105247161 Gm12415 MGI:MGI:3650585 +105247162 Gm42311 MGI:MGI:5625196 +105247163 Gm42312 MGI:MGI:5625197 +105247165 Gm42313 MGI:MGI:5625198 +105247166 Gm42314 MGI:MGI:5625199 +105247167 Gm42315 MGI:MGI:5625200 +105247168 LOC105247168 - +105247170 Gm12970 MGI:MGI:3650040 +105247171 Gm42316 MGI:MGI:5625201 +105247172 Gm42317 MGI:MGI:5625202 +105247173 Gm42318 MGI:MGI:5625203 +105247174 Gm42319 MGI:MGI:5625204 +105247175 Gm42320 MGI:MGI:5625205 +105247176 Gm42321 MGI:MGI:5625206 +105247177 LOC105247177 - +105247178 LOC105247178 - +105247179 Gm42322 MGI:MGI:5625207 +105247180 Gm42323 MGI:MGI:5625208 +105247181 Gm42324 MGI:MGI:5625209 +105247182 Gm12974 MGI:MGI:3650037 +105247183 Gm42325 MGI:MGI:5625210 +105247184 Gm42326 MGI:MGI:5625211 +105247185 Gm42327 MGI:MGI:5625212 +105247186 Gm42328 MGI:MGI:5625213 +105247187 Gm42329 MGI:MGI:5625214 +105247188 LOC105247188 - +105247190 Gm42330 MGI:MGI:5625215 +105247191 Gm13010 MGI:MGI:3651180|Ensembl:ENSMUSG00000086845 +105247192 Gm42331 MGI:MGI:5625216 +105247193 Gm42332 MGI:MGI:5625217 +105247194 Gm42333 MGI:MGI:5625218 +105247195 Gm42334 MGI:MGI:5625219 +105247196 Gm42335 MGI:MGI:5625220 +105247197 Gm42336 MGI:MGI:5625221 +105247198 Gm42337 MGI:MGI:5625222 +105247199 Gm42338 MGI:MGI:5625223 +105247200 Gm42339 MGI:MGI:5625224 +105247201 Gm42340 MGI:MGI:5625225 +105247202 Gm42341 MGI:MGI:5625226 +105247203 Gm42342 MGI:MGI:5625227 +105247204 Gm42343 MGI:MGI:5625228 +105247205 Gm42344 MGI:MGI:5625229 +105247206 Gm42345 MGI:MGI:5625230 +105247207 Gm42346 MGI:MGI:5625231 +105247208 Gm42347 MGI:MGI:5625232 +105247209 Gm13165 MGI:MGI:3650210 +105247210 Gm42348 MGI:MGI:5625233 +105247211 Gm42349 MGI:MGI:5625234 +105247212 Gm42350 MGI:MGI:5625235 +105247213 Gm42351 MGI:MGI:5625236 +105247214 Gm42352 MGI:MGI:5625237 +105247216 Gm42353 MGI:MGI:5625238 +105247217 Gm13073 MGI:MGI:3651721 +105247218 Gm42354 MGI:MGI:5625239 +105247219 Gm13070 MGI:MGI:3651970 +105247220 Gm42355 MGI:MGI:5625240 +105247221 Gm42356 MGI:MGI:5625241 +105247222 Gm42357 MGI:MGI:5625242 +105247223 Gm42358 MGI:MGI:5625243 +105247224 Gm42359 MGI:MGI:5625244 +105247225 Gm42360 MGI:MGI:5625245 +105247226 Gm42361 MGI:MGI:5625246 +105247227 LOC105247227 - +105247228 Gm42362 MGI:MGI:5625247 +105247229 Gm42363 MGI:MGI:5625248 +105247230 Gm42364 MGI:MGI:5625249 +105247231 Gm42365 MGI:MGI:5625250 +105247232 Gm42366 MGI:MGI:5625251 +105247233 Gm42367 MGI:MGI:5625252 +105247234 Gm42368 MGI:MGI:5625253 +105247237 Gm42369 MGI:MGI:5625254 +105247238 Gm42370 MGI:MGI:5625255 +105247239 Gm42371 MGI:MGI:5625256 +105247240 Gm42372 MGI:MGI:5625257 +105247241 Gm42373 MGI:MGI:5625258 +105247242 Gm42374 MGI:MGI:5625259 +105247243 Gm42375 MGI:MGI:5625260 +105247244 Gm26891 MGI:MGI:5477385 +105247245 Gm42376 MGI:MGI:5625261 +105247246 Gm42377 MGI:MGI:5625262 +105247247 Gm12762 MGI:MGI:3649976 +105247248 Gm42378 MGI:MGI:5625263 +105247249 Gm42379 MGI:MGI:5625264 +105247250 Gm42380 MGI:MGI:5625265|Ensembl:ENSMUSG00000101855 +105247251 Gm42381 MGI:MGI:5625266 +105247252 Gm42382 MGI:MGI:5625267 +105247253 LOC105247253 - +105247254 Gm42383 MGI:MGI:5625268 +105247255 Gm42384 MGI:MGI:5625269 +105247256 Gm42385 MGI:MGI:5625270 +105247264 Gm42392 MGI:MGI:5625277 +105247265 Gm42393 MGI:MGI:5625278 +105247266 Gm42394 MGI:MGI:5625279 +105247267 Gm42395 MGI:MGI:5625280 +105247268 Gm42396 MGI:MGI:5625281 +105247269 Gm42397 MGI:MGI:5625282 +105247270 Gm42398 MGI:MGI:5625283 +105247271 Gm42399 MGI:MGI:5625284 +105247272 Gm42400 MGI:MGI:5625285 +105247273 Gm42401 MGI:MGI:5625286 +105247274 Gm42402 MGI:MGI:5625287 +105247275 Gm42403 MGI:MGI:5625288 +105247276 Gm42404 MGI:MGI:5625289 +105247277 LOC105247277 Ensembl:ENSMUSG00000086757 +105247278 Gm42405 MGI:MGI:5625290 +105247279 Gm42406 MGI:MGI:5625291 +105247280 Gm42407 MGI:MGI:5625292 +105247282 LOC105247282 Ensembl:ENSMUSG00000101928|Vega:OTTMUSG00000046129 +105247283 Gm28597 MGI:MGI:5579303 +105247284 Gm42408 MGI:MGI:5625293 +105247285 Gm42409 MGI:MGI:5625294 +105247286 Gm28773 MGI:MGI:5579479 +105247287 LOC105247287 - +105247288 Gm28300 MGI:MGI:5579006|Ensembl:ENSMUSG00000099619 +105247289 Gm42410 MGI:MGI:5625295 +105247290 LOC105247290 - +105247291 LOC105247291 - +105247292 LOC105247292 - +105247293 LOC105247293 - +105247294 LOC105247294 - +105247296 LOC105247296 - +105247297 LOC105247297 - +105247298 LOC105247298 - +105247300 LOC105247300 - +105247302 LOC105247302 - +105247305 LOC105247305 - +105247308 LOC105247308 - +105247310 Gm45922 MGI:MGI:5825559 +105247312 LOC105247312 - +105247314 LOC105247314 - +105247315 LOC105247315 - +105247329 LOC105247329 - +105247334 LOC105247334 - +105247335 LOC105247335 - +105247345 LOC105247345 - +105247347 LOC105247347 - +105247366 LOC105247366 - +105247398 LOC105247398 - +105247411 LOC105247411 - +105247423 LOC105247423 - +105247436 LOC105247436 - +105247439 LOC105247439 - +105247445 LOC105247445 - +105247470 LOC105247470 - +105247524 LOC105247524 - +105247529 LOC105247529 - +105247577 LOC105247577 - +105247602 Gm11840 MGI:MGI:3651502 +105247620 LOC105247620 - +105247623 LOC105247623 - +105247631 LOC105247631 - +105247634 LOC105247634 - +105247649 LOC105247649 - +105247666 LOC105247666 - +105247676 LOC105247676 - +105247680 LOC105247680 - +105274305 LOC105274305 - +105311846 LOC105311846 - +105317033 H19-icr - +105358867 LOC105358867 - +105447647 Gm45923 MGI:MGI:5825560 +105463053 Bloodlinc MGI:MGI:3650929|Ensembl:ENSMUSG00000087330 +105463055 Erytha MGI:MGI:5508531 +105463056 Galont MGI:MGI:5508529 +105463121 Chrf - +105463122 Tip3 - +105463124 Gm45924 MGI:MGI:5825561 +105500046 Gm30731 MGI:MGI:5589890|Ensembl:ENSMUSG00000107859 +105661729 Gm45925 MGI:MGI:5825562 +105661730 Lincmd1 MGI:MGI:5818206 +105704528 Gm13090 MGI:MGI:3650445|Ensembl:ENSMUSG00000078491|Vega:OTTMUSG00000010356 +105734727 Gm27021 MGI:MGI:5504136|Ensembl:ENSMUSG00000097919|Vega:OTTMUSG00000043010 +105734728 Gm45926 MGI:MGI:5825563 +105734733 Gm13030 MGI:MGI:3651765|Ensembl:ENSMUSG00000078518|Vega:OTTMUSG00000010069 +105734734 Gm11715 MGI:MGI:3702026 +105804842 Zrs1 MGI:MGI:3028525 +105827746 Gm11729 MGI:MGI:3650942|Ensembl:ENSMUSG00000086588 +105886298 Cmc4 MGI:MGI:5637812|Ensembl:ENSMUSG00000090110|Vega:OTTMUSG00000020859 +105886299 Gm44805 MGI:MGI:5753381|Ensembl:ENSMUSG00000109350|Vega:OTTMUSG00000059275 +105940408 Gm20498 MGI:MGI:5141963|Ensembl:ENSMUSG00000021139|Vega:OTTMUSG00000035311 +105943584 Gm45927 MGI:MGI:5825564 +105948584 Pax6drr - +105948585 Gm45928 MGI:MGI:5825565 +105980007 LOC105980007 - +105980075 Gm20716 MGI:MGI:5313163 +105980076 Gm45929 MGI:MGI:5825566|Ensembl:ENSMUSG00000002345|Ensembl:ENSMUSG00000079033|Vega:OTTMUSG00000022206|Vega:OTTMUSG00000022207 +106003270 LOC106003270 - +106007486 Halr1os1 MGI:MGI:5636487 +106007487 Hobbit1 MGI:MGI:5636489 +106007488 Hotairm2 MGI:MGI:5636492 +106007489 Heater MGI:MGI:5636491 +106007492 LOC106007492 - +106007494 Hbb-3'hs1 - +106014248 Hbb-hs-62.5 - +106014250 LOC106014250 - +106014251 Gm28043 MGI:MGI:5547779 +106029237 Gm21761 MGI:MGI:5433925|Ensembl:ENSMUSG00000096175|Vega:OTTMUSG00000047881 +106049961 Sbe2 - +106049963 Sfpe1 - +106049964 Sfpe2/sbe1 - +106049965 Sbe3 - +106050031 Sbe4 - +106050032 Mrcs1 - +106050033 Mfcs3 - +106050034 Mfcs4 - +106050035 Macs1 - +106050036 Slge - +106099061 Th2-lcr - +106145633 Gp-lcr - +106345153 Gm45930 MGI:MGI:5825567 +106345154 Gm45931 MGI:MGI:5825568 +106345155 Gm45932 MGI:MGI:5825569 +106345156 Gm45933 MGI:MGI:5825570 +106345157 Gm45934 MGI:MGI:5825571 +106557447 LOC106557447 - +106635680 Apob-icr - +106660621 LOC106660621 - +106660622 LOC106660622 - +106660634 LOC106660634 - +106677017 LOC106677017 - +106677018 LOC106677018 - +106699569 Cd8_cii - +106699571 Cd8_ciii - +106699572 Cd8_civ - +106707176 As021 - +106707177 As071 - +106728413 LOC106728413 - +106736463 LOC106736463 - +106736473 LOC106736473 - +106780807 Obox4-ps1 MGI:MGI:5521014 +106780808 Obox4-ps2 MGI:MGI:5521015 +106780809 Obox4-ps3 MGI:MGI:5521023 +106780810 Obox4-ps4 MGI:MGI:5645810 +106780811 Obox4-ps5 MGI:MGI:5645811 +106780812 Obox4-ps6 MGI:MGI:5313157 +106780813 Obox4-ps7 MGI:MGI:5645812 +106780814 Obox4-ps10 MGI:MGI:5645796 +106780815 Obox4-ps24 MGI:MGI:5645797 +106780816 Obox4-ps25 MGI:MGI:5645799 +106780817 Obox4-ps26 MGI:MGI:5313070 +106780818 Obox4-ps32 MGI:MGI:5645800 +106780819 Obox4-ps34 MGI:MGI:5313069 +106780820 Obox4-ps36 MGI:MGI:5313112 +106780821 Obox4-ps37 MGI:MGI:5313111 +106780822 Obox4-ps38 MGI:MGI:5313156 +106780823 Obox4-ps39 MGI:MGI:5521101 +106804090 LOC106804090 - +106804091 LOC106804091 - +106804092 LOC106804092 - +106804093 LOC106804093 - +106804094 LOC106804094 - +106804095 LOC106804095 - +106821731 Alpha-re - +107075095 LOC107075095 - +107080631 Tyr-lcr - +107080640 Cns-2 - +107181356 Gm26566 MGI:MGI:5477060 +107197955 LOC107197955 - +107197956 LOC107197956 - +107228250 LOC107228250 - +107228251 LOC107228251 - +107303348 Gm45935 MGI:MGI:5825572 +107305670 LOC107305670 - +107305679 LOC107305679 - +107325940 LOC107325940 - +107372314 LOC107372314 - +107399302 LOC107399302 - +107403063 LOC107403063 - +107403166 LOC107403166 - +107604629 LOC107604629 - +107832853 LOC107832853 - +107963952 LOC107963952 - +107963953 LOC107963953 - +107963956 LOC107963956 - +107963957 Sox10-mcs7 - +107966118 Sox10-mcs5 - +107966120 Sox10-mcs4 - +107966122 LOC107966122 - +107966123 Sox10-mcs1c/2 - +107966126 Sox10-mcs8 - +107966127 Sox10-mcs9 - +107966128 Rer - +107980435 L1Md-A101 MGI:MGI:3771335 +107980436 C2dat1 MGI:MGI:5633903 +107980437 L1Md-A102 MGI:MGI:3771336 +107980439 LOC107980439 - +107980442 LOC107980442 - +107980444 Ecr2 - +107980446 Ser - +107983946 LOC107983946 - +107988020 LOC107988020 - +107988026 Mid1-ps1 MGI:MGI:5780070 +107988027 Gm37417 MGI:MGI:5610645 +108021847 LOC108021847 - +108021848 LOC108021848 - +108021849 LOC108021849 - +108021850 LOC108021850 - +108021851 LOC108021851 - +108021852 LOC108021852 - +108021853 LOC108021853 - +108150743 LOC108150743 - +108150744 LOC108150744 - +108150745 LOC108150745 - +108150746 LOC108150746 - +108165616 LOC108165616 - +108167304 LOC108167304 - +108167305 LOC108167305 - +108167306 LOC108167306 - +108167307 LOC108167307 - +108167308 LOC108167308 - +108167309 LOC108167309 - +108167310 LOC108167310 - +108167316 LOC108167316 - +108167318 Gm45936 MGI:MGI:5825573 +108167319 LOC108167319 - +108167320 LOC108167320 - +108167321 LOC108167321 - +108167322 LOC108167322 - +108167323 Gm45937 MGI:MGI:5825574 +108167324 Gm45938 MGI:MGI:5825575 +108167325 Gm45939 MGI:MGI:5825576 +108167326 LOC108167326 - +108167327 LOC108167327 - +108167328 Gm45940 MGI:MGI:5825577 +108167329 Gm45620 MGI:MGI:5791456|Ensembl:ENSMUSG00000110239 +108167330 Gm45941 MGI:MGI:5825578 +108167331 Gm45942 MGI:MGI:5825579 +108167332 Gm45943 MGI:MGI:5825580 +108167333 Gm45944 MGI:MGI:5825581 +108167334 Gm45945 MGI:MGI:5825582 +108167335 Gm45946 MGI:MGI:5825583 +108167336 Gm45947 MGI:MGI:5825584 +108167337 Gm45948 MGI:MGI:5825585 +108167338 Gm45949 MGI:MGI:5825586 +108167339 LOC108167339 - +108167340 LOC108167340 - +108167341 Gm45950 MGI:MGI:5825587 +108167342 LOC108167342 - +108167343 LOC108167343 - +108167344 Gm45951 MGI:MGI:5825588|Ensembl:ENSMUSG00000074863 +108167345 Gm45952 MGI:MGI:5825589 +108167346 Gm45953 MGI:MGI:5825590 +108167347 LOC108167347 - +108167348 Gm45954 MGI:MGI:5825591 +108167349 Gm44156 MGI:MGI:5690548 +108167350 Gm45955 MGI:MGI:5825592 +108167351 Gm45956 MGI:MGI:5825593 +108167352 Gm45957 MGI:MGI:5825594 +108167353 LOC108167353 - +108167354 Gm45958 MGI:MGI:5825595 +108167355 LOC108167355 - +108167356 LOC108167356 - +108167357 LOC108167357 - +108167358 LOC108167358 - +108167359 Gm45959 MGI:MGI:5825596 +108167360 Gm43837 MGI:MGI:5663974 +108167361 Gm45960 MGI:MGI:5825597 +108167362 Gm45961 MGI:MGI:5825598 +108167363 Gm45962 MGI:MGI:5825599 +108167364 Gm45708 MGI:MGI:5804823 +108167365 LOC108167365 - +108167366 LOC108167366 - +108167367 Gm45963 MGI:MGI:5825600 +108167368 LOC108167368 - +108167369 Gm45964 MGI:MGI:5825601 +108167370 Gm45965 MGI:MGI:5825602 +108167371 Gm45966 MGI:MGI:5825603 +108167372 LOC108167372 - +108167373 Gm45967 MGI:MGI:5825604 +108167374 Gm45968 MGI:MGI:5825605 +108167375 LOC108167375 - +108167376 LOC108167376 - +108167377 LOC108167377 - +108167378 LOC108167378 Ensembl:ENSMUSG00000101146|Vega:OTTMUSG00000046415 +108167379 LOC108167379 - +108167380 LOC108167380 - +108167381 LOC108167381 - +108167382 Gm45969 MGI:MGI:5825606 +108167383 LOC108167383 - +108167384 LOC108167384 - +108167385 LOC108167385 - +108167386 LOC108167386 - +108167387 LOC108167387 - +108167388 LOC108167388 - +108167389 LOC108167389 - +108167390 LOC108167390 - +108167391 LOC108167391 - +108167392 LOC108167392 - +108167393 LOC108167393 - +108167394 LOC108167394 - +108167395 LOC108167395 - +108167396 LOC108167396 - +108167397 LOC108167397 - +108167398 LOC108167398 - +108167399 LOC108167399 - +108167400 LOC108167400 - +108167401 LOC108167401 - +108167402 LOC108167402 - +108167403 LOC108167403 - +108167404 Gm45970 MGI:MGI:5825607 +108167405 LOC108167405 - +108167406 LOC108167406 - +108167407 LOC108167407 - +108167408 Gm45971 MGI:MGI:5825608 +108167409 Gm45972 MGI:MGI:5825609 +108167410 Gm45973 MGI:MGI:5825610 +108167411 Gm45974 MGI:MGI:5825611 +108167412 Gm45975 MGI:MGI:5825612 +108167413 Gm45976 MGI:MGI:5825613 +108167414 Gm45977 MGI:MGI:5825614 +108167415 Gm45978 MGI:MGI:5825615 +108167416 LOC108167416 - +108167417 Gm45979 MGI:MGI:5825616 +108167418 Gm45980 MGI:MGI:5825617 +108167419 LOC108167419 - +108167420 Gm45981 MGI:MGI:5825618 +108167421 Gm45982 MGI:MGI:5825619 +108167422 LOC108167422 - +108167423 LOC108167423 - +108167424 Gm45983 MGI:MGI:5825620 +108167425 Gm45984 MGI:MGI:5825621 +108167426 Gm45086 MGI:MGI:5753662 +108167427 Gm45985 MGI:MGI:5825622 +108167428 Gm45986 MGI:MGI:5825623 +108167429 LOC108167429 - +108167430 Gm18908 MGI:MGI:5011093 +108167431 LOC108167431 - +108167432 LOC108167432 - +108167433 Gm45987 MGI:MGI:5825624 +108167434 Gm45988 MGI:MGI:5825625 +108167435 Gm45989 MGI:MGI:5825626 +108167436 LOC108167436 - +108167437 Gm44812 MGI:MGI:5753388|Ensembl:ENSMUSG00000109021 +108167438 Gm45990 MGI:MGI:5825627 +108167439 Gm29328 MGI:MGI:5580034 +108167440 LOC108167440 - +108167441 Gm44968 MGI:MGI:5753544 +108167442 Gm45991 MGI:MGI:5825628 +108167443 LOC108167443 Ensembl:ENSMUSG00000109194 +108167444 Gm45992 MGI:MGI:5825629 +108167445 LOC108167445 - +108167446 Gm45993 MGI:MGI:5825630 +108167447 Gm44507 MGI:MGI:5753083 +108167448 Gm45994 MGI:MGI:5825631 +108167449 LOC108167449 - +108167450 LOC108167450 - +108167451 Gm45995 MGI:MGI:5825632 +108167452 Gm45996 MGI:MGI:5825633 +108167453 Gm45997 MGI:MGI:5825634 +108167454 LOC108167454 - +108167455 Gm44781 MGI:MGI:5753357 +108167456 Gm45998 MGI:MGI:5825635 +108167457 Gm45999 MGI:MGI:5825636 +108167458 Gm44867 MGI:MGI:5753443 +108167459 Gm46000 MGI:MGI:5825637 +108167460 Gm46001 MGI:MGI:5825638 +108167461 LOC108167461 - +108167462 Gm46002 MGI:MGI:5825639 +108167463 Gm46003 MGI:MGI:5825640 +108167464 LOC108167464 - +108167465 Gm46004 MGI:MGI:5825641 +108167466 Gm45618 MGI:MGI:5791454|Ensembl:ENSMUSG00000109859|Vega:OTTMUSG00000060159 +108167467 Gm46005 MGI:MGI:5825642 +108167468 Gm46006 MGI:MGI:5825643 +108167469 Gm45549 MGI:MGI:5791385 +108167470 Gm44513 MGI:MGI:5753089 +108167471 Gm44978 MGI:MGI:5753554 +108167472 Gm26217 MGI:MGI:5455994 +108167473 Gm45401 MGI:MGI:5791237 +108167474 Gm45596 MGI:MGI:5791432 +108167475 Gm46007 MGI:MGI:5825644 +108167476 Gm46008 MGI:MGI:5825645 +108167477 Gm46009 MGI:MGI:5825646 +108167478 Gm45034 MGI:MGI:5753610 +108167479 Thap8p - +108167480 Gm46010 MGI:MGI:5825647 +108167481 LOC108167481 - +108167482 Gm46011 MGI:MGI:5825648 +108167483 Gm46012 MGI:MGI:5825649 +108167484 Gm46013 MGI:MGI:5825650 +108167485 LOC108167485 - +108167486 Gm46014 MGI:MGI:5825651 +108167487 Gm15115 MGI:MGI:3642219 +108167488 LOC108167488 - +108167489 Gm45598 MGI:MGI:5791434 +108167490 Gm44254 MGI:MGI:5690646 +108167491 LOC108167491 - +108167492 Gm46015 MGI:MGI:5825652 +108167493 LOC108167493 - +108167494 LOC108167494 - +108167495 LOC108167495 - +108167496 LOC108167496 - +108167497 Gm46016 MGI:MGI:5825653 +108167498 Topbp1-ps1 MGI:MGI:5578765 +108167499 Gm46017 MGI:MGI:5825654 +108167500 Gm44705 MGI:MGI:5753281 +108167501 LOC108167501 - +108167502 Gm46018 MGI:MGI:5825655 +108167503 Gm46019 MGI:MGI:5825656 +108167504 Gm46020 MGI:MGI:5825657 +108167505 Gm46021 MGI:MGI:5825658 +108167506 Gm46022 MGI:MGI:5825659 +108167507 Gm46023 MGI:MGI:5825660 +108167508 Gm46024 MGI:MGI:5825661 +108167509 Gm46025 MGI:MGI:5825662 +108167510 Gm46026 MGI:MGI:5825663 +108167511 LOC108167511 - +108167512 LOC108167512 - +108167513 Gm46027 MGI:MGI:5825664 +108167514 Gm46028 MGI:MGI:5825665 +108167515 Gm45700 MGI:MGI:5804815 +108167516 n-TEttc7 MGI:MGI:4413860 +108167517 Gm46029 MGI:MGI:5825666 +108167518 LOC108167518 - +108167519 Gm46030 MGI:MGI:5825667 +108167520 Gm45420 MGI:MGI:5791256 +108167521 Gm46031 MGI:MGI:5825668 +108167522 Gm17023 MGI:MGI:4937850 +108167523 Gm46032 MGI:MGI:5825669 +108167524 Gm46033 MGI:MGI:5825670 +108167525 Gm46034 MGI:MGI:5825671 +108167526 Gm46035 MGI:MGI:5825672 +108167527 Gm46036 MGI:MGI:5825673 +108167528 Gm46037 MGI:MGI:5825674 +108167529 Gm45470 MGI:MGI:5791306 +108167530 Gm46038 MGI:MGI:5825675 +108167531 Gm46039 MGI:MGI:5825676 +108167532 Gm46040 MGI:MGI:5825677 +108167533 Gm46041 MGI:MGI:5825678 +108167534 LOC108167534 - +108167535 Gm45734 MGI:MGI:5804849 +108167536 Gm46042 MGI:MGI:5825679 +108167537 Gm46043 MGI:MGI:5825680 +108167538 Gm45434 MGI:MGI:5791270 +108167539 Gm46044 MGI:MGI:5825681 +108167540 Gm46045 MGI:MGI:5825682 +108167541 Gm46046 MGI:MGI:5825683 +108167542 Gm46047 MGI:MGI:5825684 +108167543 Gm46048 MGI:MGI:5825685 +108167544 Gm28511 MGI:MGI:5579217 +108167545 Gm45910 MGI:MGI:5805025 +108167546 LOC108167546 - +108167547 Gm46049 MGI:MGI:5825686 +108167548 Gm45855 MGI:MGI:5804970 +108167549 LOC108167549 - +108167550 Gm38250 MGI:MGI:5611478 +108167551 Gm46050 MGI:MGI:5825687 +108167552 Gm46051 MGI:MGI:5825688 +108167553 LOC108167553 - +108167554 Gm46052 MGI:MGI:5825689 +108167555 Gm46053 MGI:MGI:5825690 +108167556 Gm46054 MGI:MGI:5825691 +108167557 Gm46055 MGI:MGI:5825692 +108167558 Gm46056 MGI:MGI:5825693 +108167559 Gm46057 MGI:MGI:5825694 +108167560 Gm46058 MGI:MGI:5825695 +108167561 Gm46059 MGI:MGI:5825696 +108167562 Gm46060 MGI:MGI:5825697 +108167563 Gm46061 MGI:MGI:5825698 +108167564 LOC108167564 - +108167565 Gm17149 MGI:MGI:4937976 +108167566 Gm46062 MGI:MGI:5825699 +108167567 LOC108167567 - +108167568 Gm46063 MGI:MGI:5825700 +108167569 Gm45651 MGI:MGI:5791487 +108167570 Gm45445 MGI:MGI:5791281 +108167571 Gm43263 MGI:MGI:5663400 +108167572 LOC108167572 - +108167573 Gm45574 MGI:MGI:5791410 +108167574 Gm46064 MGI:MGI:5825701 +108167575 Gm46065 MGI:MGI:5825702 +108167576 Gm46066 MGI:MGI:5825703 +108167577 LOC108167577 - +108167578 LOC108167578 - +108167579 Gm46067 MGI:MGI:5825704 +108167580 Gm46068 MGI:MGI:5825705 +108167581 Gm46069 MGI:MGI:5825706 +108167582 Gm45405 MGI:MGI:5791241 +108167583 Gm46070 MGI:MGI:5825707 +108167584 Gm45723 MGI:MGI:5804838 +108167585 Gm46071 MGI:MGI:5825708 +108167586 Gm46072 MGI:MGI:5825709 +108167587 Gm46073 MGI:MGI:5825710 +108167588 LOC108167588 - +108167589 Gm46074 MGI:MGI:5825711 +108167590 Gm46075 MGI:MGI:5825712 +108167591 Gm46076 MGI:MGI:5825713 +108167592 LOC108167592 - +108167593 Gm46077 MGI:MGI:5825714 +108167594 LOC108167594 - +108167595 LOC108167595 - +108167596 Gm28341 MGI:MGI:5579047 +108167597 LOC108167597 - +108167598 LOC108167598 - +108167599 Gm15183 MGI:MGI:3705481 +108167600 Gm46078 MGI:MGI:5825715 +108167601 Gm28363 MGI:MGI:5579069 +108167602 Gm46079 MGI:MGI:5825716 +108167603 Gm46080 MGI:MGI:5825717 +108167604 LOC108167604 - +108167605 LOC108167605 - +108167606 LOC108167606 - +108167607 Gm38051 MGI:MGI:5611279 +108167608 Gm46081 MGI:MGI:5825718 +108167609 LOC108167609 - +108167610 Gm46082 MGI:MGI:5825719 +108167611 Gm46083 MGI:MGI:5825720 +108167612 Gm26983 MGI:MGI:5504098 +108167613 LOC108167613 - +108167614 Gm46084 MGI:MGI:5825721 +108167615 Gm46085 MGI:MGI:5825722 +108167616 Gm46086 MGI:MGI:5825723 +108167617 LOC108167617 - +108167618 Gm46087 MGI:MGI:5825724 +108167619 LOC108167619 - +108167620 Gm46088 MGI:MGI:5825725 +108167621 Gm46089 MGI:MGI:5825726 +108167622 Gm46090 MGI:MGI:5825727 +108167623 Gm46091 MGI:MGI:5825728 +108167624 LOC108167624 - +108167625 Gm46092 MGI:MGI:5825729 +108167626 Gm46093 MGI:MGI:5825730 +108167627 Gm46094 MGI:MGI:5825731 +108167628 Gm28364 MGI:MGI:5579070 +108167629 LOC108167629 Ensembl:ENSMUSG00000100562 +108167630 Gm46095 MGI:MGI:5825732 +108167631 Gm46096 MGI:MGI:5825733 +108167632 Gm46097 MGI:MGI:5825734 +108167633 Gm46098 MGI:MGI:5825735 +108167634 Gm46099 MGI:MGI:5825736 +108167635 LOC108167635 - +108167636 Gm46100 MGI:MGI:5825737 +108167637 Gm46101 MGI:MGI:5825738 +108167638 Gm46102 MGI:MGI:5825739 +108167639 Gm46103 MGI:MGI:5825740 +108167640 Gm46104 MGI:MGI:5825741 +108167641 Gm46105 MGI:MGI:5825742 +108167642 Gm46106 MGI:MGI:5825743 +108167643 LOC108167643 - +108167644 Gm46107 MGI:MGI:5825744 +108167645 Gm46108 MGI:MGI:5825745 +108167646 LOC108167646 - +108167647 LOC108167647 - +108167648 LOC108167648 - +108167649 Gm46109 MGI:MGI:5825746 +108167650 Gm46110 MGI:MGI:5825747 +108167651 Gm46111 MGI:MGI:5825748 +108167652 Gm46112 MGI:MGI:5825749 +108167653 Gm46113 MGI:MGI:5825750 +108167654 Gm46114 MGI:MGI:5825751 +108167655 Gm46115 MGI:MGI:5825752 +108167656 LOC108167656 - +108167657 Gm46116 MGI:MGI:5825753 +108167658 Gm46117 MGI:MGI:5825754 +108167659 LOC108167659 - +108167660 Gm25640 MGI:MGI:5455417 +108167661 LOC108167661 - +108167662 Gm46118 MGI:MGI:5825755 +108167663 Gm46119 MGI:MGI:5825756 +108167664 Gm46120 MGI:MGI:5825757 +108167665 LOC108167665 - +108167666 Gm46121 MGI:MGI:5825758 +108167667 Gm46122 MGI:MGI:5825759 +108167668 Gm46123 MGI:MGI:5825760 +108167669 Gm46124 MGI:MGI:5825761 +108167670 Gm17415 MGI:MGI:4937049 +108167671 LOC108167671 - +108167672 LOC108167672 - +108167673 LOC108167673 - +108167674 LOC108167674 - +108167675 Gm46125 MGI:MGI:5825762 +108167676 LOC108167676 - +108167677 Gm46126 MGI:MGI:5825763 +108167678 Gm46127 MGI:MGI:5825764 +108167679 Gm46128 MGI:MGI:5825765 +108167680 Gm46129 MGI:MGI:5825766 +108167681 Gm46130 MGI:MGI:5825767 +108167682 LOC108167682 - +108167683 Gm46131 MGI:MGI:5825768 +108167684 LOC108167684 - +108167685 Gm46132 MGI:MGI:5825769 +108167686 Gm46133 MGI:MGI:5825770 +108167687 LOC108167687 - +108167688 Gm46134 MGI:MGI:5825771 +108167689 LOC108167689 - +108167690 Gm26797 MGI:MGI:5477291 +108167691 Gm46135 MGI:MGI:5825772 +108167692 Gm46136 MGI:MGI:5825773 +108167693 Gm46137 MGI:MGI:5825774 +108167694 LOC108167694 - +108167695 Gm20620 MGI:MGI:5313067 +108167696 Gm16218 MGI:MGI:3802109 +108167697 LOC108167697 - +108167698 Gm46138 MGI:MGI:5825775 +108167699 LOC108167699 - +108167700 Gm46139 MGI:MGI:5825776 +108167701 Gm46140 MGI:MGI:5825777 +108167702 LOC108167702 - +108167703 Gm46141 MGI:MGI:5825778 +108167704 LOC108167704 - +108167705 Gm46142 MGI:MGI:5825779 +108167706 Gm46143 MGI:MGI:5825780 +108167707 Gm46144 MGI:MGI:5825781 +108167708 Gm46145 MGI:MGI:5825782 +108167709 Gm46146 MGI:MGI:5825783 +108167710 Gm29454 MGI:MGI:5580160 +108167711 Gm46147 MGI:MGI:5825784 +108167712 LOC108167712 - +108167713 Gm46148 MGI:MGI:5825785 +108167714 Gm46149 MGI:MGI:5825786 +108167715 Gm29658 MGI:MGI:5580364 +108167716 Gm29387 MGI:MGI:5580093 +108167717 Gm46150 MGI:MGI:5825787 +108167718 Gm46151 MGI:MGI:5825788 +108167719 Gm46152 MGI:MGI:5825789 +108167720 Gm46153 MGI:MGI:5825790 +108167721 LOC108167721 - +108167722 Gm46154 MGI:MGI:5825791 +108167723 Gm46155 MGI:MGI:5825792 +108167724 Gm29487 MGI:MGI:5580193 +108167725 Gm46156 MGI:MGI:5825793 +108167726 Gm37120 MGI:MGI:5610348 +108167727 Gm46157 MGI:MGI:5825794 +108167728 Gm46158 MGI:MGI:5825795 +108167729 Gm46159 MGI:MGI:5825796 +108167730 Gm46160 MGI:MGI:5825797 +108167731 Gm46161 MGI:MGI:5825798 +108167732 Gm46162 MGI:MGI:5825799 +108167733 LOC108167733 - +108167734 Gm46163 MGI:MGI:5825800 +108167735 Gm46164 MGI:MGI:5825801 +108167736 LOC108167736 - +108167737 Gm46165 MGI:MGI:5825802 +108167738 Gm46166 MGI:MGI:5825803 +108167739 LOC108167739 - +108167740 LOC108167740 - +108167741 Gm46167 MGI:MGI:5825804 +108167742 Gm46168 MGI:MGI:5825805 +108167743 Gm46169 MGI:MGI:5825806 +108167744 Gm46170 MGI:MGI:5825807 +108167745 Gm46171 MGI:MGI:5825808 +108167746 Gm46172 MGI:MGI:5825809 +108167747 Gm46173 MGI:MGI:5825810 +108167748 Gm46174 MGI:MGI:5825811 +108167749 LOC108167749 - +108167750 LOC108167750 - +108167751 LOC108167751 - +108167752 Gm46175 MGI:MGI:5825812 +108167753 Gm46176 MGI:MGI:5825813 +108167754 Gm46177 MGI:MGI:5825814 +108167755 Gm46178 MGI:MGI:5825815 +108167756 Gm46179 MGI:MGI:5825816 +108167757 Gm46180 MGI:MGI:5825817 +108167758 Gm46181 MGI:MGI:5825818 +108167759 Gm46182 MGI:MGI:5825819 +108167760 LOC108167760 - +108167761 Gm46183 MGI:MGI:5825820 +108167762 Gm46184 MGI:MGI:5825821 +108167763 Gm46185 MGI:MGI:5825822 +108167764 Gm46186 MGI:MGI:5825823 +108167765 Gm46187 MGI:MGI:5825824 +108167766 Gm46188 MGI:MGI:5825825 +108167767 LOC108167767 - +108167768 LOC108167768 - +108167769 LOC108167769 - +108167770 Gm46189 MGI:MGI:5825826 +108167771 Gm46190 MGI:MGI:5825827 +108167772 Gm46191 MGI:MGI:5825828 +108167773 Gm46192 MGI:MGI:5825829 +108167774 Gm46193 MGI:MGI:5825830 +108167775 LOC108167775 - +108167776 Gm46194 MGI:MGI:5825831 +108167777 Gm46195 MGI:MGI:5825832 +108167778 Gm46196 MGI:MGI:5825833 +108167779 Gm46197 MGI:MGI:5825834 +108167780 Gm46198 MGI:MGI:5825835 +108167781 Gm46199 MGI:MGI:5825836 +108167782 Gm46200 MGI:MGI:5825837 +108167783 Gm46201 MGI:MGI:5825838 +108167784 Gm46202 MGI:MGI:5825839 +108167785 Gm46203 MGI:MGI:5825840 +108167786 Gm46204 MGI:MGI:5825841 +108167787 Gm46205 MGI:MGI:5825842 +108167788 Gm46206 MGI:MGI:5825843 +108167789 LOC108167789 Ensembl:ENSMUSG00000094632|Vega:OTTMUSG00000056650 +108167790 Gm46207 MGI:MGI:5825844 +108167791 Gm46208 MGI:MGI:5825845 +108167792 Gm46209 MGI:MGI:5825846 +108167793 Gm46210 MGI:MGI:5825847 +108167794 Gm46211 MGI:MGI:5825848 +108167795 Gm46212 MGI:MGI:5825849 +108167796 Gm46213 MGI:MGI:5825850 +108167797 Gm46214 MGI:MGI:5825851 +108167798 Gm46215 MGI:MGI:5825852 +108167799 Gm46216 MGI:MGI:5825853 +108167800 Gm46217 MGI:MGI:5825854 +108167801 LOC108167801 - +108167802 Gm46218 MGI:MGI:5825855 +108167803 Gm46219 MGI:MGI:5825856 +108167804 Gm46220 MGI:MGI:5825857 +108167805 LOC108167805 - +108167806 Gm46221 MGI:MGI:5825858 +108167807 Gm46222 MGI:MGI:5825859 +108167808 Gm28343 MGI:MGI:5579049 +108167809 Gm46223 MGI:MGI:5825860 +108167810 Gm46224 MGI:MGI:5825861 +108167811 Gm46225 MGI:MGI:5825862 +108167812 Gm46226 MGI:MGI:5825863 +108167813 Gm46227 MGI:MGI:5825864 +108167814 LOC108167814 - +108167815 Gm46228 MGI:MGI:5825865 +108167816 Gm46229 MGI:MGI:5825866 +108167817 Gm46230 MGI:MGI:5825867 +108167818 Gm46231 MGI:MGI:5825868 +108167819 Gm46232 MGI:MGI:5825869 +108167820 Gm46233 MGI:MGI:5825870 +108167821 Gm46234 MGI:MGI:5825871 +108167822 Gm46235 MGI:MGI:5825872 +108167823 Gm46236 MGI:MGI:5825873 +108167824 Gm46237 MGI:MGI:5825874 +108167825 LOC108167825 Ensembl:ENSMUSG00000090230 +108167826 Gm16269 MGI:MGI:3826558 +108167827 Gm46238 MGI:MGI:5825875 +108167828 LOC108167828 - +108167829 Gm46239 MGI:MGI:5825876 +108167830 Gm46240 MGI:MGI:5825877 +108167831 Gm46241 MGI:MGI:5825878 +108167832 Gm29389 MGI:MGI:5580095 +108167833 Gm46242 MGI:MGI:5825879 +108167834 Gm46243 MGI:MGI:5825880 +108167835 LOC108167835 - +108167836 Gm46244 MGI:MGI:5825881 +108167837 Gm46245 MGI:MGI:5825882 +108167838 Gm46246 MGI:MGI:5825883 +108167839 Gm46247 MGI:MGI:5825884 +108167840 Gm37450 MGI:MGI:5610678 +108167841 LOC108167841 - +108167842 Gm46248 MGI:MGI:5825885 +108167843 Gm38022 MGI:MGI:5611250 +108167844 LOC108167844 - +108167845 Gm46249 MGI:MGI:5825886 +108167846 Gm46250 MGI:MGI:5825887 +108167847 Gm46251 MGI:MGI:5825888 +108167848 LOC108167848 Ensembl:ENSMUSG00000072915|Vega:OTTMUSG00000005767 +108167849 Gm46252 MGI:MGI:5825889 +108167850 LOC108167850 - +108167851 Gm46253 MGI:MGI:5825890 +108167852 LOC108167852 - +108167853 Gm46254 MGI:MGI:5825891 +108167854 LOC108167854 - +108167855 Gm46255 MGI:MGI:5825892 +108167856 Gm46256 MGI:MGI:5825893 +108167857 LOC108167857 - +108167858 Gm46257 MGI:MGI:5825894 +108167859 LOC108167859 - +108167860 Efcab13 MGI:MGI:5816263 +108167861 Gm12030 MGI:MGI:3651405 +108167862 Gm46258 MGI:MGI:5825895 +108167863 Gm46259 MGI:MGI:5825896 +108167864 Gm12210 MGI:MGI:3650677 +108167865 Gm46260 MGI:MGI:5825897 +108167866 Gm46261 MGI:MGI:5825898 +108167867 Gm46262 MGI:MGI:5825899 +108167868 LOC108167868 - +108167869 LOC108167869 - +108167870 Gm46263 MGI:MGI:5825900 +108167871 LOC108167871 - +108167872 LOC108167872 - +108167873 Gm46264 MGI:MGI:5825901 +108167874 LOC108167874 - +108167875 Gm11399 MGI:MGI:3650744 +108167876 LOC108167876 - +108167877 LOC108167877 - +108167878 Gm46265 MGI:MGI:5825902 +108167879 Gm46266 MGI:MGI:5825903 +108167880 Gm46267 MGI:MGI:5825904 +108167881 Gm46268 MGI:MGI:5825905 +108167882 Gm46269 MGI:MGI:5825906 +108167883 Gm46270 MGI:MGI:5825907 +108167884 LOC108167884 - +108167885 Gm46271 MGI:MGI:5825908 +108167886 Gm46272 MGI:MGI:5825909 +108167887 Gm46273 MGI:MGI:5825910 +108167888 LOC108167888 - +108167889 Gm46274 MGI:MGI:5825911 +108167890 LOC108167890 - +108167891 Gm12094 MGI:MGI:3650094 +108167892 Gm12095 MGI:MGI:3651296 +108167893 Gm46275 MGI:MGI:5825912 +108167894 Gm46276 MGI:MGI:5825913 +108167895 Gm46277 MGI:MGI:5825914 +108167896 Gm46278 MGI:MGI:5825915 +108167897 Gm46279 MGI:MGI:5825916 +108167898 Gm46280 MGI:MGI:5825917 +108167899 Gm46281 MGI:MGI:5825918 +108167900 LOC108167900 - +108167901 LOC108167901 - +108167902 Gm46282 MGI:MGI:5825919 +108167903 Gm12619 MGI:MGI:3649878 +108167904 Gm46283 MGI:MGI:5825920 +108167905 Gm46284 MGI:MGI:5825921 +108167906 LOC108167906 - +108167907 LOC108167907 - +108167908 Gm46285 MGI:MGI:5825922 +108167909 Gm46286 MGI:MGI:5825923 +108167910 LOC108167910 - +108167911 Gm46287 MGI:MGI:5825924 +108167912 LOC108167912 - +108167913 LOC108167913 - +108167914 Gm46288 MGI:MGI:5825925 +108167915 LOC108167915 - +108167916 LOC108167916 - +108167917 Gm46289 MGI:MGI:5825926 +108167918 Gm46290 MGI:MGI:5825927 +108167919 Gm46291 MGI:MGI:5825928 +108167920 LOC108167920 - +108167921 Gm46292 MGI:MGI:5825929 +108167922 LOC108167922 - +108167923 Gm46293 MGI:MGI:5825930 +108167924 Gm11613 MGI:MGI:3651819 +108167925 Gm46294 MGI:MGI:5825931 +108167926 Gm46295 MGI:MGI:5825932 +108167927 LOC108167927 - +108167928 Gm46296 MGI:MGI:5825933 +108167929 LOC108167929 - +108167930 LOC108167930 - +108167931 LOC108167931 Ensembl:ENSMUSG00000087184 +108167932 Gm46297 MGI:MGI:5825934 +108167933 LOC108167933 - +108167934 Gm46298 MGI:MGI:5825935 +108167935 LOC108167935 - +108167936 Gm46299 MGI:MGI:5825936 +108167937 Gm46300 MGI:MGI:5825937 +108167938 Gm46301 MGI:MGI:5825938 +108167939 Gm46302 MGI:MGI:5825939 +108167940 Gm11750 MGI:MGI:3650640 +108167941 Gm46303 MGI:MGI:5825940 +108167942 Gm46304 MGI:MGI:5825941 +108167943 n-TDgtc10 MGI:MGI:4413761 +108167944 n-TQttg6 MGI:MGI:4413840 +108167945 Gm46305 MGI:MGI:5825942 +108167946 Gm46306 MGI:MGI:5825943 +108167947 Gm46307 MGI:MGI:5825944 +108167948 Gm46308 MGI:MGI:5825945 +108167949 Gm46309 MGI:MGI:5825946 +108167950 LOC108167950 - +108167951 Gm46310 MGI:MGI:5825947 +108167952 LOC108167952 - +108167953 Gm46311 MGI:MGI:5825948 +108167954 Gm46312 MGI:MGI:5825949 +108167955 Gm46313 MGI:MGI:5825950 +108167956 Gm46314 MGI:MGI:5825951 +108167957 Gm46315 MGI:MGI:5825952 +108167958 Gm46316 MGI:MGI:5825953 +108167959 Gm46317 MGI:MGI:5825954 +108167960 Gm46318 MGI:MGI:5825955 +108167961 Gm46319 MGI:MGI:5825956 +108167962 Gm17053 MGI:MGI:4937880 +108167963 Gm46320 MGI:MGI:5825957 +108167964 Gm46321 MGI:MGI:5825958 +108167965 Gm46322 MGI:MGI:5825959 +108167966 Gm46323 MGI:MGI:5825960 +108167967 Gm46324 MGI:MGI:5825961 +108167968 Gm46325 MGI:MGI:5825962 +108167969 Gm46326 MGI:MGI:5825963 +108167970 Gm46327 MGI:MGI:5825964 +108167971 Gm46328 MGI:MGI:5825965|Ensembl:ENSMUSG00000112053 +108167972 Gm46329 MGI:MGI:5825966|Ensembl:ENSMUSG00000112704 +108167973 LOC108167973 - +108167974 LOC108167974 - +108167975 Gm46330 MGI:MGI:5825967 +108167976 Gm46331 MGI:MGI:5825968 +108167977 LOC108167977 - +108167978 Gm46332 MGI:MGI:5825969 +108167979 Gm46333 MGI:MGI:5825970 +108167980 Gm46334 MGI:MGI:5825971 +108167981 Gm46335 MGI:MGI:5825972 +108167982 Gm46336 MGI:MGI:5825973 +108167983 LOC108167983 - +108167984 Gm46337 MGI:MGI:5825974 +108167985 Gm46338 MGI:MGI:5825975 +108167986 Gm46339 MGI:MGI:5825976 +108167987 LOC108167987 - +108167988 LOC108167988 - +108167989 Gm46340 MGI:MGI:5825977 +108167990 LOC108167990 - +108167991 Gm46341 MGI:MGI:5825978 +108167992 Gm46342 MGI:MGI:5825979 +108167993 Gm46343 MGI:MGI:5825980 +108167994 Gm46344 MGI:MGI:5825981 +108167995 Gm46345 MGI:MGI:5825982 +108167996 Gm46346 MGI:MGI:5825983 +108167997 Gm46347 MGI:MGI:5825984 +108167998 Gm46348 MGI:MGI:5825985 +108167999 Gm46349 MGI:MGI:5825986 +108168000 Gm46350 MGI:MGI:5825987 +108168001 Gm46351 MGI:MGI:5825988 +108168002 Gm46352 MGI:MGI:5825989 +108168003 Gm46353 MGI:MGI:5825990 +108168004 LOC108168004 - +108168005 Gm46354 MGI:MGI:5825991 +108168006 Gm46355 MGI:MGI:5825992 +108168007 Gm46356 MGI:MGI:5825993 +108168008 Gm46357 MGI:MGI:5825994 +108168009 Gm46358 MGI:MGI:5825995 +108168010 Gm46359 MGI:MGI:5825996 +108168011 Gm46360 MGI:MGI:5825997 +108168012 Gm46361 MGI:MGI:5825998 +108168013 Gm46362 MGI:MGI:5825999 +108168014 Gm46363 MGI:MGI:5826000 +108168015 Gm46364 MGI:MGI:5826001 +108168016 Gm46365 MGI:MGI:5826002 +108168017 Gm46366 MGI:MGI:5826003 +108168018 Gm46367 MGI:MGI:5826004 +108168019 Gm46368 MGI:MGI:5826005 +108168020 Gm46369 MGI:MGI:5826006 +108168021 Gm46370 MGI:MGI:5826007 +108168022 Gm46371 MGI:MGI:5826008 +108168023 LOC108168023 - +108168024 Gm46372 MGI:MGI:5826009 +108168025 Gm46373 MGI:MGI:5826010 +108168026 Gm46374 MGI:MGI:5826011 +108168027 Gm46375 MGI:MGI:5826012 +108168028 Gm46376 MGI:MGI:5826013 +108168029 Gm46377 MGI:MGI:5826014 +108168030 Gm46378 MGI:MGI:5826015 +108168031 Gm46379 MGI:MGI:5826016 +108168032 Gm46380 MGI:MGI:5826017 +108168033 Gm46381 MGI:MGI:5826018 +108168034 Gm46382 MGI:MGI:5826019 +108168035 LOC108168035 - +108168036 Gm46383 MGI:MGI:5826020 +108168037 n-TEctc2 MGI:MGI:4413842 +108168038 LOC108168038 - +108168039 LOC108168039 - +108168040 LOC108168040 - +108168041 Gm46384 MGI:MGI:5826021 +108168042 Gm46385 MGI:MGI:5826022 +108168043 LOC108168043 - +108168044 LOC108168044 - +108168045 Gm46386 MGI:MGI:5826023 +108168046 Gm46387 MGI:MGI:5826024 +108168047 Gm46388 MGI:MGI:5826025 +108168048 Gm46389 MGI:MGI:5826026 +108168049 Gm46390 MGI:MGI:5826027 +108168050 Gm46391 MGI:MGI:5826028 +108168051 LOC108168051 - +108168052 Gm46392 MGI:MGI:5826029 +108168053 Gm46393 MGI:MGI:5826030 +108168054 Gm46394 MGI:MGI:5826031 +108168055 LOC108168055 - +108168056 Gm46395 MGI:MGI:5826032 +108168057 Gm46396 MGI:MGI:5826033 +108168058 LOC108168058 - +108168059 Gm46397 MGI:MGI:5826034 +108168060 Gm46398 MGI:MGI:5826035 +108168061 Gm46399 MGI:MGI:5826036 +108168062 Gm46400 MGI:MGI:5826037 +108168063 Gm46401 MGI:MGI:5826038 +108168064 LOC108168064 - +108168065 LOC108168065 - +108168066 Gm46402 MGI:MGI:5826039 +108168067 Gm46403 MGI:MGI:5826040 +108168068 Gm11274 MGI:MGI:3649225 +108168069 Gm46404 MGI:MGI:5826041 +108168070 LOC108168070 - +108168071 Gm46405 MGI:MGI:5826042 +108168072 Gm46406 MGI:MGI:5826043 +108168073 LOC108168073 - +108168074 Gm46407 MGI:MGI:5826044 +108168075 Gm46408 MGI:MGI:5826045 +108168076 Gm46409 MGI:MGI:5826046 +108168077 Gm46410 MGI:MGI:5826047 +108168078 Gm46411 MGI:MGI:5826048 +108168079 Gm28707 MGI:MGI:5579413 +108168080 Gm46412 MGI:MGI:5826049 +108168081 LOC108168081 - +108168082 Gm46413 MGI:MGI:5826050 +108168083 Gm46414 MGI:MGI:5826051 +108168084 Gm46415 MGI:MGI:5826052 +108168085 Gm46416 MGI:MGI:5826053 +108168086 Gm46417 MGI:MGI:5826054 +108168087 Gm46418 MGI:MGI:5826055 +108168088 Gm46419 MGI:MGI:5826056 +108168089 Gm46420 MGI:MGI:5826057 +108168090 LOC108168090 - +108168091 Gm46421 MGI:MGI:5826058 +108168092 Gm46422 MGI:MGI:5826059 +108168093 Gm46423 MGI:MGI:5826060 +108168094 Gm46424 MGI:MGI:5826061 +108168095 LOC108168095 - +108168096 Gm46425 MGI:MGI:5826062 +108168097 Gm46426 MGI:MGI:5826063 +108168098 Gm46427 MGI:MGI:5826064 +108168099 Gm46428 MGI:MGI:5826065 +108168100 Gm46429 MGI:MGI:5826066 +108168101 Gm46430 MGI:MGI:5826067 +108168102 Gm46431 MGI:MGI:5826068 +108168103 Gm46432 MGI:MGI:5826069 +108168104 Gm46433 MGI:MGI:5826070 +108168105 LOC108168105 - +108168106 Gm46434 MGI:MGI:5826071 +108168107 Gm46435 MGI:MGI:5826072 +108168108 LOC108168108 - +108168109 Gm46436 MGI:MGI:5826073 +108168110 Gm46437 MGI:MGI:5826074 +108168111 LOC108168111 - +108168112 Gm46438 MGI:MGI:5826075 +108168113 Gm46439 MGI:MGI:5826076 +108168114 LOC108168114 Ensembl:ENSMUSG00000095847 +108168115 Gm46440 MGI:MGI:5826077 +108168116 n-TLtaa2 MGI:MGI:4413942 +108168117 n-TIaat11 MGI:MGI:4413912 +108168118 n-TIaat10 MGI:MGI:4413911 +108168119 n-TFgaa1 MGI:MGI:4413996 +108168120 n-TItat14 MGI:MGI:4413915 +108168121 n-TRtct3 MGI:MGI:4413736 +108168122 n-TStga2 MGI:MGI:4414045 +108168123 n-TMcat10 MGI:MGI:4413987 +108168124 n-TQctg8 MGI:MGI:4413832 +108168125 n-TDgtc13 MGI:MGI:4413764 +108168126 n-TSaga1 MGI:MGI:4414030 +108168127 n-TDgtc12 MGI:MGI:4413763 +108168128 n-TSaga8 MGI:MGI:4414028 +108168129 n-TTagt4 MGI:MGI:4414051 +108168130 n-TMcat2 MGI:MGI:4413979 +108168132 n-TDgtc11 MGI:MGI:4413762 +108168133 n-TLcaa2 MGI:MGI:4413929 +108168134 n-TSaga5 MGI:MGI:4414025 +108168135 n-TQctg10 MGI:MGI:4413834 +108168136 n-TSaga6 MGI:MGI:4414026 +108168137 n-TKttt22 MGI:MGI:4413969 +108168138 n-TMcat8 MGI:MGI:4413985 +108168139 Gm46441 MGI:MGI:5826078 +108168140 Gm46442 MGI:MGI:5826079 +108168141 Gm46443 MGI:MGI:5826080 +108168142 Gm46444 MGI:MGI:5826081 +108168143 Gm46445 MGI:MGI:5826082 +108168144 Gm46446 MGI:MGI:5826083 +108168145 LOC108168145 - +108168146 Gm46447 MGI:MGI:5826084 +108168147 Gm46448 MGI:MGI:5826085 +108168148 LOC108168148 Ensembl:ENSMUSG00000094925|Vega:OTTMUSG00000036327 +108168149 LOC108168149 - +108168150 Gm46449 MGI:MGI:5826086 +108168151 Gm46450 MGI:MGI:5826087 +108168152 LOC108168152 - +108168153 LOC108168153 - +108168154 LOC108168154 - +108168155 LOC108168155 Ensembl:ENSMUSG00000091477|Vega:OTTMUSG00000036382 +108168156 LOC108168156 - +108168157 Gm46451 MGI:MGI:5826088 +108168158 Gm46452 MGI:MGI:5826089 +108168159 Gm46453 MGI:MGI:5826090 +108168160 Gm46454 MGI:MGI:5826091 +108168161 LOC108168161 - +108168162 Gm43305 MGI:MGI:5663442 +108168163 Gm46455 MGI:MGI:5826092 +108168164 LOC108168164 Ensembl:ENSMUSG00000021983 +108168165 Gm46456 MGI:MGI:5826093 +108168166 Gm46457 MGI:MGI:5826094 +108168167 Gm46458 MGI:MGI:5826095 +108168168 Gm46459 MGI:MGI:5826096 +108168169 Gm46460 MGI:MGI:5826097 +108168170 Gm46461 MGI:MGI:5826098 +108168171 Gm46462 MGI:MGI:5826099 +108168172 Gm46463 MGI:MGI:5826100 +108168173 Gm46464 MGI:MGI:5826101 +108168174 Gm46465 MGI:MGI:5826102 +108168175 Gm46466 MGI:MGI:5826103 +108168176 Gm10338 MGI:MGI:3642676|Ensembl:ENSMUSG00000094706 +108168177 Gm46467 MGI:MGI:5826104 +108168178 Gm46468 MGI:MGI:5826105 +108168179 Gm46469 MGI:MGI:5826106 +108168180 Gm46470 MGI:MGI:5826107 +108168181 Gm46471 MGI:MGI:5826108 +108168182 Gm46472 MGI:MGI:5826109 +108168183 Gm46473 MGI:MGI:5826110 +108168184 LOC108168184 - +108168185 LOC108168185 - +108168186 LOC108168186 Ensembl:ENSMUSG00000091700|Vega:OTTMUSG00000036238 +108168187 LOC108168187 Ensembl:ENSMUSG00000090627|Vega:OTTMUSG00000036148 +108168188 Gm46474 MGI:MGI:5826111 +108168189 LOC108168189 - +108168190 LOC108168190 - +108168191 Gm46475 MGI:MGI:5826112 +108168192 Gm46476 MGI:MGI:5826113 +108168193 Gm46477 MGI:MGI:5826114 +108168194 Gm46478 MGI:MGI:5826115 +108168195 Gm46479 MGI:MGI:5826116 +108168196 Gm46480 MGI:MGI:5826117 +108168197 Gm46481 MGI:MGI:5826118 +108168198 Gm46482 MGI:MGI:5826119 +108168199 Gm46483 MGI:MGI:5826120 +108168200 Gm46484 MGI:MGI:5826121 +108168201 Gm46485 MGI:MGI:5826122 +108168202 Gm46486 MGI:MGI:5826123 +108168203 Gm46487 MGI:MGI:5826124 +108168204 Gm46488 MGI:MGI:5826125 +108168205 Gm46489 MGI:MGI:5826126 +108168206 Gm46490 MGI:MGI:5826127 +108168207 Gm46491 MGI:MGI:5826128 +108168208 Gm45521 MGI:MGI:5791357|Ensembl:ENSMUSG00000109649|Vega:OTTMUSG00000061078 +108168209 Gm46492 MGI:MGI:5826129 +108168210 Gm46493 MGI:MGI:5826130 +108168211 Gm46494 MGI:MGI:5826131 +108168212 Gm46495 MGI:MGI:5826132 +108168213 Gm46496 MGI:MGI:5826133 +108168214 Gm46497 MGI:MGI:5826134 +108168215 Gm46498 MGI:MGI:5826135 +108168216 Gm46499 MGI:MGI:5826136 +108168217 Gm28117 MGI:MGI:5578823 +108168218 LOC108168218 - +108168219 Gm46500 MGI:MGI:5826137 +108168220 Gm46501 MGI:MGI:5826138 +108168221 Gm27825 MGI:MGI:5531207 +108168222 Gm28023 MGI:MGI:5531405 +108168223 Gm46502 MGI:MGI:5826139 +108168224 Gm46503 MGI:MGI:5826140 +108168225 Gm26513 MGI:MGI:5477007 +108168226 Gm46504 MGI:MGI:5826141 +108168227 Gm46505 MGI:MGI:5826142 +108168228 Gm46506 MGI:MGI:5826143 +108168229 Gm46507 MGI:MGI:5826144 +108168230 Gm46508 MGI:MGI:5826145 +108168231 Gm46509 MGI:MGI:5826146 +108168232 Gm46510 MGI:MGI:5826147 +108168233 LOC108168233 Ensembl:ENSMUSG00000085442 +108168234 Gm46511 MGI:MGI:5826148 +108168235 LOC108168235 - +108168236 Gm46512 MGI:MGI:5826149 +108168237 Gm46513 MGI:MGI:5826150 +108168238 Gm26766 MGI:MGI:5477260 +108168239 Gm46514 MGI:MGI:5826151 +108168240 Gm46515 MGI:MGI:5826152 +108168241 Gm46516 MGI:MGI:5826153 +108168242 Gm46517 MGI:MGI:5826154 +108168243 Gm46518 MGI:MGI:5826155 +108168244 Gm46519 MGI:MGI:5826156 +108168245 Gm46520 MGI:MGI:5826157 +108168246 Gm46521 MGI:MGI:5826158 +108168247 Gm46522 MGI:MGI:5826159 +108168248 Gm46523 MGI:MGI:5826160 +108168249 Gm46524 MGI:MGI:5826161 +108168250 Gm46525 MGI:MGI:5826162 +108168251 Gm46526 MGI:MGI:5826163 +108168252 Gm46527 MGI:MGI:5826164 +108168253 Gm46528 MGI:MGI:5826165 +108168254 Gm29666 MGI:MGI:5580372 +108168255 Gm46529 MGI:MGI:5826166 +108168256 Gm46530 MGI:MGI:5826167 +108168257 Gm46531 MGI:MGI:5826168 +108168258 Gm46532 MGI:MGI:5826169 +108168259 LOC108168259 - +108168260 Gm46533 MGI:MGI:5826170 +108168261 Gm46534 MGI:MGI:5826171 +108168262 Gm46535 MGI:MGI:5826172 +108168263 Gm46536 MGI:MGI:5826173 +108168264 Gm46537 MGI:MGI:5826174 +108168265 Gm46538 MGI:MGI:5826175 +108168266 LOC108168266 - +108168267 LOC108168267 - +108168268 Gm46539 MGI:MGI:5826176 +108168269 n-TMcat3 MGI:MGI:4413980 +108168270 Gm15696 MGI:MGI:3783137 +108168271 Gm46540 MGI:MGI:5826177 +108168272 LOC108168272 - +108168273 Gm46541 MGI:MGI:5826178 +108168274 Gm46542 MGI:MGI:5826179 +108168275 LOC108168275 - +108168276 Gm46543 MGI:MGI:5826180 +108168277 Gm46544 MGI:MGI:5826181 +108168278 Gm46545 MGI:MGI:5826182 +108168279 Gm46546 MGI:MGI:5826183 +108168280 Gm46547 MGI:MGI:5826184 +108168281 LOC108168281 - +108168282 LOC108168282 - +108168283 Gm46548 MGI:MGI:5826185 +108168284 Gm46549 MGI:MGI:5826186 +108168285 Gm46550 MGI:MGI:5826187 +108168286 LOC108168286 - +108168287 Gm46551 MGI:MGI:5826188 +108168288 LOC108168288 - +108168289 LOC108168289 - +108168290 Gm46552 MGI:MGI:5826189 +108168291 Gm46553 MGI:MGI:5826190 +108168292 Gm46554 MGI:MGI:5826191 +108168293 LOC108168293 - +108168294 Gm46555 MGI:MGI:5826192 +108168295 Gm46556 MGI:MGI:5826193 +108168296 Gm46557 MGI:MGI:5826194 +108168297 Gm46558 MGI:MGI:5826195 +108168298 Gm46559 MGI:MGI:5826196 +108168299 Gm46560 MGI:MGI:5826197 +108168300 Gm46561 MGI:MGI:5826198 +108168301 Gm46562 MGI:MGI:5826199 +108168302 Gm46563 MGI:MGI:5826200 +108168303 Gm46564 MGI:MGI:5826201 +108168304 LOC108168304 Ensembl:ENSMUSG00000071671 +108168305 Gm46565 MGI:MGI:5826202 +108168306 Gm46566 MGI:MGI:5826203 +108168307 Gm46567 MGI:MGI:5826204 +108168308 Gm46568 MGI:MGI:5826205 +108168309 Gm46569 MGI:MGI:5826206 +108168310 Gm46570 MGI:MGI:5826207 +108168311 Gm46571 MGI:MGI:5826208 +108168312 LOC108168312 - +108168313 LOC108168313 - +108168314 Gm46572 MGI:MGI:5826209 +108168315 Gm46573 MGI:MGI:5826210 +108168316 Gm46574 MGI:MGI:5826211 +108168317 LOC108168317 - +108168318 Gm46575 MGI:MGI:5826212 +108168319 Gm46576 MGI:MGI:5826213 +108168320 Gm46577 MGI:MGI:5826214 +108168321 Gm46578 MGI:MGI:5826215 +108168322 Gm46579 MGI:MGI:5826216 +108168323 Gm46580 MGI:MGI:5826217 +108168324 Gm46581 MGI:MGI:5826218 +108168325 Gm46582 MGI:MGI:5826219 +108168326 Gm46583 MGI:MGI:5826220 +108168327 Gm46584 MGI:MGI:5826221 +108168328 Gm46585 MGI:MGI:5826222 +108168329 Gm46586 MGI:MGI:5826223 +108168330 Gm46587 MGI:MGI:5826224 +108168331 Gm46588 MGI:MGI:5826225 +108168332 Gm46589 MGI:MGI:5826226 +108168333 LOC108168333 - +108168334 Gm46590 MGI:MGI:5826227 +108168335 Gm46591 MGI:MGI:5826228 +108168336 Gm46592 MGI:MGI:5826229 +108168337 Gm46593 MGI:MGI:5826230 +108168338 Gm46594 MGI:MGI:5826231 +108168339 Gm46595 MGI:MGI:5826232 +108168340 Gm46596 MGI:MGI:5826233 +108168341 LOC108168341 - +108168342 Gm46597 MGI:MGI:5826234 +108168343 Gm46598 MGI:MGI:5826235 +108168344 Gm46599 MGI:MGI:5826236 +108168345 Gm46600 MGI:MGI:5826237 +108168346 Gm46601 MGI:MGI:5826238 +108168347 LOC108168347 - +108168348 Gm46602 MGI:MGI:5826239 +108168349 Gm46603 MGI:MGI:5826240 +108168350 Gm27217 MGI:MGI:5521060 +108168351 LOC108168351 - +108168352 LOC108168352 - +108168353 LOC108168353 - +108168354 Gm46604 MGI:MGI:5826241 +108168355 Gm46605 MGI:MGI:5826242 +108168356 Gm46606 MGI:MGI:5826243 +108168357 Gm46607 MGI:MGI:5826244 +108168358 Gm46608 MGI:MGI:5826245 +108168359 Gm46609 MGI:MGI:5826246 +108168360 Gm46610 MGI:MGI:5826247 +108168361 LOC108168361 - +108168362 n-TVcac3 MGI:MGI:4414094 +108168363 LOC108168363 - +108168364 Gm46611 MGI:MGI:5826248 +108168365 Gm46612 MGI:MGI:5826249 +108168366 LOC108168366 - +108168367 LOC108168367 - +108168368 Gm46613 MGI:MGI:5826250 +108168369 Gm46614 MGI:MGI:5826251 +108168370 Gm46615 MGI:MGI:5826252 +108168371 Gm46616 MGI:MGI:5826253 +108168372 LOC108168372 - +108168373 Gm46617 MGI:MGI:5826254 +108168374 Gm46618 MGI:MGI:5826255 +108168375 Gm46619 MGI:MGI:5826256 +108168376 Gm46620 MGI:MGI:5826257 +108168377 Gm46621 MGI:MGI:5826258 +108168378 Gm46622 MGI:MGI:5826259 +108168379 Gm46623 MGI:MGI:5826260 +108168380 Gm46624 MGI:MGI:5826261 +108168381 Gm46625 MGI:MGI:5826262 +108168382 Gm46626 MGI:MGI:5826263 +108168383 Gm46627 MGI:MGI:5826264 +108168384 LOC108168384 - +108168385 Gm46628 MGI:MGI:5826265 +108168386 Gm44577 MGI:MGI:5753153 +108168387 Gm46629 MGI:MGI:5826266 +108168388 Gm46630 MGI:MGI:5826267 +108168389 Gm46631 MGI:MGI:5826268 +108168390 Gm46632 MGI:MGI:5826269 +108168391 Gm46633 MGI:MGI:5826270 +108168392 Gm46634 MGI:MGI:5826271 +108168393 LOC108168393 Ensembl:ENSMUSG00000073532 +108168394 Gm46635 MGI:MGI:5826272 +108168395 Gm45871 MGI:MGI:5804986|Ensembl:ENSMUSG00000110277|Vega:OTTMUSG00000061331 +108168396 Gm46636 MGI:MGI:5826273 +108168397 Gm46637 MGI:MGI:5826274 +108168398 Gm46638 MGI:MGI:5826275 +108168399 Gm46639 MGI:MGI:5826276 +108168400 Gm46640 MGI:MGI:5826277 +108168401 Gm46641 MGI:MGI:5826278 +108168402 Gm46642 MGI:MGI:5826279 +108168403 Gm46643 MGI:MGI:5826280 +108168404 Gm46644 MGI:MGI:5826281 +108168405 LOC108168405 - +108168406 Gm46645 MGI:MGI:5826282 +108168407 Gm46646 MGI:MGI:5826283 +108168408 Gm46647 MGI:MGI:5826284 +108168409 Gm46648 MGI:MGI:5826285 +108168410 Gm46649 MGI:MGI:5826286 +108168411 Gm46650 MGI:MGI:5826287 +108168412 Gm46651 MGI:MGI:5826288 +108168413 Gm46652 MGI:MGI:5826289 +108168414 Gm46653 MGI:MGI:5826290 +108168415 Gm46654 MGI:MGI:5826291 +108168416 Gm46655 MGI:MGI:5826292 +108168417 Gm46656 MGI:MGI:5826293 +108168418 Gm46657 MGI:MGI:5826294 +108168419 Gm46658 MGI:MGI:5826295 +108168420 Gm46659 MGI:MGI:5826296 +108168421 Gm46660 MGI:MGI:5826297 +108168422 Gm46661 MGI:MGI:5826298 +108168423 Gm46662 MGI:MGI:5826299 +108168424 Gm46663 MGI:MGI:5826300 +108168425 LOC108168425 - +108168426 Gm46664 MGI:MGI:5826301 +108168427 Gm46665 MGI:MGI:5826302 +108168428 LOC108168428 - +108168429 Gm46666 MGI:MGI:5826303 +108168430 Gm46667 MGI:MGI:5826304 +108168431 Gm46668 MGI:MGI:5826305 +108168432 Gm46669 MGI:MGI:5826306 +108168433 Gm46670 MGI:MGI:5826307 +108168434 LOC108168434 - +108168435 Gm46671 MGI:MGI:5826308 +108168436 Gm46672 MGI:MGI:5826309 +108168437 Gm46673 MGI:MGI:5826310 +108168438 Gm14687 MGI:MGI:3705460 +108168439 Gm14721 MGI:MGI:3705501 +108168440 Gm14727 MGI:MGI:3705576 +108168441 Gm46674 MGI:MGI:5826311 +108168442 Gm46675 MGI:MGI:5826312 +108168443 LOC108168443 - +108168444 Gm46676 MGI:MGI:5826313 +108168445 Gm46677 MGI:MGI:5826314 +108168446 LOC108168446 - +108168447 Gm46678 MGI:MGI:5826315 +108168448 LOC108168448 - +108168449 LOC108168449 - +108168450 LOC108168450 - +108168451 Gm15038 MGI:MGI:3705689 +108168452 LOC108168452 - +108168453 Gm15262 MGI:MGI:3705232 +108168454 Gm15216 MGI:MGI:3705427 +108168455 Gm46679 MGI:MGI:5826316 +108168456 LOC108168456 - +108168457 Gm46680 MGI:MGI:5826317 +108168458 LOC108168458 - +108168459 LOC108168459 Ensembl:ENSMUSG00000093817 +108168460 LOC108168460 - +108168461 Gm46681 MGI:MGI:5826318 +108168462 LOC108168462 - +108168463 Gm46682 MGI:MGI:5826319 +108168464 LOC108168464 - +108168465 Gm14846 MGI:MGI:3705595 +108168466 LOC108168466 - +108168467 Gm46683 MGI:MGI:5826320 +108168468 LOC108168468 Ensembl:ENSMUSG00000095659|Vega:OTTMUSG00000056765 +108168469 LOC108168469 - +108168470 LOC108168470 - +108168471 LOC108168471 - +108168472 LOC108168472 - +108168473 LOC108168473 - +108168474 Gm46684 MGI:MGI:5826321 +108168475 LOC108168475 - +108168476 Gm14883 MGI:MGI:3705547 +108168477 LOC108168477 - +108168478 Gm14853 MGI:MGI:3708095 +108168479 Gm46685 MGI:MGI:5826322 +108168480 Gm46686 MGI:MGI:5826323 +108168481 LOC108168481 - +108168482 Gm46687 MGI:MGI:5826324 +108168483 Gm46688 MGI:MGI:5826325 +108168484 Gm46689 MGI:MGI:5826326 +108168485 LOC108168485 - +108168486 LOC108168486 - +108168487 Gm46690 MGI:MGI:5826327 +108168488 Gm46691 MGI:MGI:5826328 +108168489 Gm46692 MGI:MGI:5826329 +108168490 LOC108168490 - +108168491 Gm14362 MGI:MGI:3650345 +108168492 Gm46693 MGI:MGI:5826330 +108168493 Gm14355 MGI:MGI:3650965 +108168494 LOC108168494 - +108168495 Gm46694 MGI:MGI:5826331 +108168496 LOC108168496 - +108168497 LOC108168497 - +108168498 Gm46695 MGI:MGI:5826332 +108168499 Gm46696 MGI:MGI:5826333 +108168500 n-TPtgg3 MGI:MGI:4414015 +108168501 Gm46697 MGI:MGI:5826334 +108168502 Gm46698 MGI:MGI:5826335 +108168503 Gm46699 MGI:MGI:5826336 +108168504 Gm46700 MGI:MGI:5826337 +108168505 Gm46701 MGI:MGI:5826338 +108168506 LOC108168506 - +108168507 Gm46702 MGI:MGI:5826339 +108168508 Gm46703 MGI:MGI:5826340 +108168509 LOC108168509 Ensembl:ENSMUSG00000101933|Vega:OTTMUSG00000048739 +108168510 LOC108168510 Ensembl:ENSMUSG00000101157|Vega:OTTMUSG00000047552 +108168511 LOC108168511 Ensembl:ENSMUSG00000093895|Vega:OTTMUSG00000047738 +108168512 Gm46704 MGI:MGI:5826341 +108168513 Gm46705 MGI:MGI:5826342 +108168514 Gm46706 MGI:MGI:5826343 +108168515 LOC108168515 Ensembl:ENSMUSG00000095979|Vega:OTTMUSG00000048310 +108168516 LOC108168516 - +108168517 Gm46707 MGI:MGI:5826344 +108168518 Gm46708 MGI:MGI:5826345 +108168519 Gm46709 MGI:MGI:5826346 +108168520 LOC108168520 Ensembl:ENSMUSG00000094821|Vega:OTTMUSG00000045537 +108168521 LOC108168521 - +108168522 Gm46710 MGI:MGI:5826347 +108168523 Gm46711 MGI:MGI:5826348 +108168524 LOC108168524 - +108168525 LOC108168525 Ensembl:ENSMUSG00000096016|Vega:OTTMUSG00000045919 +108168526 Gm29452 MGI:MGI:5580158 +108168527 LOC108168527 Ensembl:ENSMUSG00000094616|Vega:OTTMUSG00000046010 +108168528 LOC108168528 - +108168529 Gm46712 MGI:MGI:5826349 +108168530 LOC108168530 Ensembl:ENSMUSG00000096902|Vega:OTTMUSG00000046106 +108168531 Gm46713 MGI:MGI:5826350 +108168532 LOC108168532 - +108168533 LOC108168533 Ensembl:ENSMUSG00000094647|Vega:OTTMUSG00000046545 +108168534 Gm46714 MGI:MGI:5826351 +108168535 LOC108168535 - +108168536 LOC108168536 - +108168537 LOC108168537 - +108168538 LOC108168538 - +108168539 LOC108168539 - +108168540 LOC108168540 - +108168541 LOC108168541 - +108168542 LOC108168542 - +108168543 LOC108168543 - +108168544 LOC108168544 - +108168545 LOC108168545 Ensembl:ENSMUSG00000095793|Vega:OTTMUSG00000048976 +108168546 LOC108168546 - +108168547 LOC108168547 Ensembl:ENSMUSG00000101158|Vega:OTTMUSG00000049410 +108168548 LOC108168548 Ensembl:ENSMUSG00000100892|Vega:OTTMUSG00000047643 +108168549 LOC108168549 - +108168550 LOC108168550 - +108168551 LOC108168551 Ensembl:ENSMUSG00000099541|Vega:OTTMUSG00000049517 +108168552 LOC108168552 Ensembl:ENSMUSG00000100055|Vega:OTTMUSG00000049619 +108168553 LOC108168553 Ensembl:ENSMUSG00000102122|Vega:OTTMUSG00000048375 +108168554 LOC108168554 Ensembl:ENSMUSG00000094294|Vega:OTTMUSG00000042963 +108168555 LOC108168555 Ensembl:ENSMUSG00000096650|Vega:OTTMUSG00000048839 +108168556 LOC108168556 - +108168557 LOC108168557 Ensembl:ENSMUSG00000100856|Vega:OTTMUSG00000045578 +108168558 LOC108168558 Ensembl:ENSMUSG00000100485|Vega:OTTMUSG00000048425 +108168559 LOC108168559 Ensembl:ENSMUSG00000094399|Vega:OTTMUSG00000047083 +108168560 Gm28091 MGI:MGI:5578797|Ensembl:ENSMUSG00000100565 +108168561 LOC108168561 - +108168562 LOC108168562 - +108168563 LOC108168563 - +108168564 LOC108168564 - +108168565 LOC108168565 - +108168566 LOC108168566 - +108168567 LOC108168567 - +108168568 LOC108168568 - +108168569 LOC108168569 - +108168570 LOC108168570 - +108168571 LOC108168571 - +108168572 Gm46715 MGI:MGI:5826352 +108168573 Gm46716 MGI:MGI:5826353 +108168574 LOC108168574 - +108168575 LOC108168575 - +108168576 LOC108168576 - +108168577 LOC108168577 - +108168578 LOC108168578 Ensembl:ENSMUSG00000095324|Vega:OTTMUSG00000046121 +108168579 LOC108168579 Ensembl:ENSMUSG00000094660|Vega:OTTMUSG00000045415 +108168580 LOC108168580 - +108168581 LOC108168581 - +108168582 LOC108168582 Ensembl:ENSMUSG00000099894|Vega:OTTMUSG00000046720 +108168583 LOC108168583 - +108168584 LOC108168584 - +108168585 LOC108168585 - +108168586 LOC108168586 - +108168587 LOC108168587 - +108168588 LOC108168588 - +108168589 LOC108168589 - +108168590 LOC108168590 Ensembl:ENSMUSG00000100972|Vega:OTTMUSG00000048191 +108168591 Gm21794 MGI:MGI:5433958 +108168592 LOC108168592 - +108168593 LOC108168593 - +108168594 LOC108168594 Ensembl:ENSMUSG00000096769|Vega:OTTMUSG00000048384 +108168595 LOC108168595 - +108168596 LOC108168596 - +108168597 LOC108168597 - +108168598 LOC108168598 - +108168599 LOC108168599 - +108168600 LOC108168600 - +108168601 LOC108168601 - +108168602 LOC108168602 - +108168603 LOC108168603 - +108168604 LOC108168604 - +108168605 LOC108168605 - +108168606 LOC108168606 - +108168607 LOC108168607 - +108168608 LOC108168608 - +108168609 LOC108168609 - +108168610 LOC108168610 - +108168611 LOC108168611 - +108168612 LOC108168612 - +108168613 LOC108168613 - +108168614 LOC108168614 Ensembl:ENSMUSG00000095508|Vega:OTTMUSG00000048647 +108168615 LOC108168615 - +108168616 LOC108168616 - +108168617 LOC108168617 - +108168618 LOC108168618 - +108168619 LOC108168619 - +108168620 LOC108168620 - +108168621 LOC108168621 - +108168622 LOC108168622 - +108168623 LOC108168623 - +108168624 LOC108168624 - +108168625 LOC108168625 - +108168626 LOC108168626 - +108168627 LOC108168627 - +108168628 LOC108168628 - +108168629 LOC108168629 - +108168630 LOC108168630 - +108168631 LOC108168631 - +108168632 LOC108168632 - +108168633 LOC108168633 - +108168634 LOC108168634 - +108168635 LOC108168635 - +108168636 Gm38185 MGI:MGI:5611413 +108168637 LOC108168637 Ensembl:ENSMUSG00000095242|Vega:OTTMUSG00000046758 +108168638 LOC108168638 Ensembl:ENSMUSG00000096686|Vega:OTTMUSG00000045702 +108168639 LOC108168639 - +108168640 LOC108168640 - +108168641 LOC108168641 - +108168642 LOC108168642 Ensembl:ENSMUSG00000093927|Vega:OTTMUSG00000045635 +108168643 Gm29315 MGI:MGI:5580021|Ensembl:ENSMUSG00000101642 +108168644 Gm46717 MGI:MGI:5826354 +108168645 LOC108168645 - +108168646 LOC108168646 - +108168647 LOC108168647 - +108168648 LOC108168648 - +108168649 LOC108168649 - +108168650 LOC108168650 - +108168651 LOC108168651 - +108168652 LOC108168652 - +108168653 LOC108168653 - +108168654 LOC108168654 - +108168655 LOC108168655 - +108168656 LOC108168656 - +108168657 LOC108168657 - +108168658 LOC108168658 Ensembl:ENSMUSG00000096268|Vega:OTTMUSG00000045650 +108168659 LOC108168659 - +108168660 LOC108168660 - +108168661 LOC108168661 - +108168662 LOC108168662 Ensembl:ENSMUSG00000095785|Vega:OTTMUSG00000045794 +108168663 LOC108168663 - +108168664 LOC108168664 - +108168665 LOC108168665 - +108168666 LOC108168666 - +108168667 LOC108168667 - +108168668 LOC108168668 - +108168669 LOC108168669 Ensembl:ENSMUSG00000094484|Vega:OTTMUSG00000045867 +108168670 LOC108168670 - +108168671 LOC108168671 - +108168672 Gm46718 MGI:MGI:5826355 +108168673 LOC108168673 - +108168674 LOC108168674 - +108168675 LOC108168675 - +108168676 LOC108168676 - +108168677 LOC108168677 - +108168678 LOC108168678 - +108168679 LOC108168679 - +108168680 LOC108168680 - +108168681 LOC108168681 Ensembl:ENSMUSG00000094303 +108168682 LOC108168682 - +108168683 LOC108168683 Ensembl:ENSMUSG00000094383 +108168684 LOC108168684 - +108168685 LOC108168685 Ensembl:ENSMUSG00000091585 +108168686 LOC108168686 - +108168687 LOC108168687 - +108168688 Gm46719 MGI:MGI:5826356 +108168689 LOC108168689 - +108168690 LOC108168690 - +108168691 LOC108168691 - +108168692 LOC108168692 - +108168693 LOC108168693 - +108168694 Gm46720 MGI:MGI:5826357 +108168695 Gm15781 MGI:MGI:3783223 +108168696 Gm46721 MGI:MGI:5826358 +108168697 LOC108168697 - +108168698 LOC108168698 - +108168699 LOC108168699 - +108168700 LOC108168700 - +108168701 LOC108168701 - +108168702 Trnav-cac - +108168703 LOC108168703 - +108168704 LOC108168704 - +108168705 LOC108168705 - +108168706 LOC108168706 - +108168707 Gm46722 MGI:MGI:5826359 +108168708 LOC108168708 - +108168709 LOC108168709 - +108168710 Gm12972 MGI:MGI:3650043 +108168711 Gm46723 MGI:MGI:5826360 +108168712 Gm46724 MGI:MGI:5826361 +108168713 LOC108168713 - +108168714 LOC108168714 - +108168715 LOC108168715 - +108168716 LOC108168716 - +108168717 LOC108168717 - +108168718 LOC108168718 - +108168719 LOC108168719 - +108168720 LOC108168720 - +108168721 LOC108168721 - +108168722 LOC108168722 - +108168723 LOC108168723 - +108168724 LOC108168724 - +108168725 LOC108168725 - +108168726 LOC108168726 - +108168727 Gm46725 MGI:MGI:5826362 +108168728 LOC108168728 - +108168729 Gm46726 MGI:MGI:5826363 +108168730 LOC108168730 - +108168731 LOC108168731 - +108168732 LOC108168732 - +108168733 Gm46727 MGI:MGI:5826364 +108168734 LOC108168734 - +108168735 LOC108168735 - +108168736 Gm46728 MGI:MGI:5826365 +108168737 Gm46729 MGI:MGI:5826366 +108168738 Gm46730 MGI:MGI:5826367 +108168739 Gm13291 MGI:MGI:3649284 +108168740 Gm46731 MGI:MGI:5826368 +108168741 Gm46732 MGI:MGI:5826369 +108168742 LOC108168742 - +108168743 Gm46733 MGI:MGI:5826370 +108168744 Gm46734 MGI:MGI:5826371 +108168745 LOC108168745 - +108168746 LOC108168746 - +108168747 Gm46735 MGI:MGI:5826372 +108168748 Gm46736 MGI:MGI:5826373 +108168749 Gm13586 MGI:MGI:3649994 +108168750 Gm46737 MGI:MGI:5826374 +108168751 LOC108168751 - +108168752 Gm46738 MGI:MGI:5826375 +108168753 Gm46739 MGI:MGI:5826376 +108168754 LOC108168754 - +108168755 Gm46740 MGI:MGI:5826377 +108168756 Gm46741 MGI:MGI:5826378 +108168757 Gm46742 MGI:MGI:5826379 +108168758 LOC108168758 - +108168759 LOC108168759 - +108168760 LOC108168760 - +108168761 Gm46743 MGI:MGI:5826380 +108168762 LOC108168762 - +108168763 LOC108168763 - +108168764 LOC108168764 - +108168765 Gm46744 MGI:MGI:5826381 +108168766 Gm46745 MGI:MGI:5826382 +108168767 Gm46746 MGI:MGI:5826383 +108168768 Gm46747 MGI:MGI:5826384 +108168769 Gm46748 MGI:MGI:5826385 +108168770 LOC108168770 - +108168771 LOC108168771 - +108168772 Gm46749 MGI:MGI:5826386 +108168773 Gm46750 MGI:MGI:5826387 +108168774 Gm46751 MGI:MGI:5826388 +108168775 Gm46752 MGI:MGI:5826389 +108168776 Gm46753 MGI:MGI:5826390 +108168777 LOC108168777 - +108168778 Gm46754 MGI:MGI:5826391 +108168779 LOC108168779 - +108168780 LOC108168780 - +108168781 Gm46755 MGI:MGI:5826392 +108168782 Gm21985 MGI:MGI:5439454 +108168783 Gm46756 MGI:MGI:5826393 +108168784 Gm46757 MGI:MGI:5826394 +108168785 LOC108168785 - +108168786 Gm46758 MGI:MGI:5826395 +108168787 Gm46759 MGI:MGI:5826396 +108168788 Gm46760 MGI:MGI:5826397 +108168789 Gm46761 MGI:MGI:5826398 +108168790 Gm46762 MGI:MGI:5826399 +108168791 LOC108168791 - +108168792 Gm46763 MGI:MGI:5826400 +108168793 Gm46764 MGI:MGI:5826401 +108168794 Gm46765 MGI:MGI:5826402 +108168795 Gm46766 MGI:MGI:5826403 +108168796 Gm14102 MGI:MGI:3651501 +108168797 Gm46767 MGI:MGI:5826404 +108168798 LOC108168798 - +108168799 LOC108168799 - +108168800 LOC108168800 - +108168801 Gm46768 MGI:MGI:5826405 +108168802 LOC108168802 - +108168803 Gm46769 MGI:MGI:5826406 +108168804 Gm46770 MGI:MGI:5826407 +108168805 Gm46771 MGI:MGI:5826408 +108168806 Gm45609 MGI:MGI:5791445 +108168807 Gm46772 MGI:MGI:5826409 +108168808 LOC108168808 - +108168809 LOC108168809 - +108168810 Gm46773 MGI:MGI:5826410 +108168811 Gm14228 MGI:MGI:3649960 +108168812 Gm46774 MGI:MGI:5826411 +108168813 Gm46775 MGI:MGI:5826412 +108168814 Gm46776 MGI:MGI:5826413 +108168815 LOC108168815 - +108168816 LOC108168816 - +108168817 Gm46777 MGI:MGI:5826414 +108168818 Gm46778 MGI:MGI:5826415 +108168819 LOC108168819 - +108168820 LOC108168820 - +108168821 Gm46779 MGI:MGI:5826416 +108168822 Gm46780 MGI:MGI:5826417 +108168823 Gm46781 MGI:MGI:5826418 +108168824 LOC108168824 - +108168825 Gm46782 MGI:MGI:5826419 +108168826 Gm46783 MGI:MGI:5826420 +108168827 LOC108168827 - +108168828 Gm13218 MGI:MGI:3651679 +108168829 Gm46784 MGI:MGI:5826421 +108168830 Gm46785 MGI:MGI:5826422 +108168831 LOC108168831 - +108168832 LOC108168832 - +108168833 LOC108168833 - +108168834 Gm46786 MGI:MGI:5826423 +108168835 LOC108168835 - +108168836 Gm46787 MGI:MGI:5826424 +108168837 LOC108168837 - +108168838 Gm46788 MGI:MGI:5826425 +108168839 Gm46789 MGI:MGI:5826426 +108168840 LOC108168840 - +108168841 LOC108168841 - +108168842 Gm46790 MGI:MGI:5826427 +108168843 Gm46791 MGI:MGI:5826428 +108168844 Gm46792 MGI:MGI:5826429 +108168845 Gm46793 MGI:MGI:5826430 +108168846 Gm46794 MGI:MGI:5826431 +108168847 Gm46795 MGI:MGI:5826432 +108168848 Gm37996 MGI:MGI:5611224 +108168849 Gm37358 MGI:MGI:5610586 +108168850 Gm37636 MGI:MGI:5610864 +108168851 Gm38237 MGI:MGI:5611465 +108168852 Gm38247 MGI:MGI:5611475 +108168853 Gm43471 MGI:MGI:5663608 +108168854 Gm42579 MGI:MGI:5662716 +108168855 LOC108168855 - +108168856 LOC108168856 - +108168857 Gm46796 MGI:MGI:5826433 +108168858 LOC108168858 - +108168859 Gm46797 MGI:MGI:5826434 +108168860 LOC108168860 - +108168861 Gm15462 MGI:MGI:3705271|Ensembl:ENSMUSG00000086189 +108168862 Gm37770 MGI:MGI:5610998 +108168863 Gm46798 MGI:MGI:5826435 +108168864 Gm46799 MGI:MGI:5826436 +108168865 Gm46800 MGI:MGI:5826437 +108168866 Gm46801 MGI:MGI:5826438 +108168867 Gm46802 MGI:MGI:5826439 +108168868 LOC108168868 - +108168869 Gm46803 MGI:MGI:5826440 +108168870 Gm43549 MGI:MGI:5663686 +108168871 Gm46804 MGI:MGI:5826441 +108168872 Gm46805 MGI:MGI:5826442 +108168873 Gm46806 MGI:MGI:5826443 +108168874 Gm46807 MGI:MGI:5826444 +108168875 Gm46808 MGI:MGI:5826445 +108168876 Gm46809 MGI:MGI:5826446 +108168877 Gm46810 MGI:MGI:5826447 +108168878 Gm21956 MGI:MGI:5439425 +108168879 Gm46811 MGI:MGI:5826448 +108168880 Gm46812 MGI:MGI:5826449 +108168881 Gm46813 MGI:MGI:5826450 +108168882 Gm46814 MGI:MGI:5826451 +108168883 LOC108168883 - +108168884 Gm37500 MGI:MGI:5610728 +108168885 Gm46815 MGI:MGI:5826452 +108168886 Gm46816 MGI:MGI:5826453 +108168887 Gm46817 MGI:MGI:5826454 +108168888 Gm46818 MGI:MGI:5826455 +108168889 LOC108168889 - +108168890 Gm46819 MGI:MGI:5826456 +108168891 Gm12498 MGI:MGI:3650533 +108168892 Gm46820 MGI:MGI:5826457 +108168893 Gm46821 MGI:MGI:5826458 +108168894 Gm46822 MGI:MGI:5826459 +108168895 Gm43568 MGI:MGI:5663705|Ensembl:ENSMUSG00000106365 +108168896 LOC108168896 - +108168897 LOC108168897 - +108168898 Gm46823 MGI:MGI:5826460 +108168899 Gm46824 MGI:MGI:5826461 +108168900 Gm46825 MGI:MGI:5826462 +108168901 Gm43116 MGI:MGI:5663253 +108168902 Gm46826 MGI:MGI:5826463 +108168903 Gm46827 MGI:MGI:5826464 +108168904 Gm43403 MGI:MGI:5663540 +108168905 Gm46828 MGI:MGI:5826465 +108168906 Gm43707 MGI:MGI:5663844 +108168907 Gm46829 MGI:MGI:5826466 +108168908 LOC108168908 - +108168909 Gm46830 MGI:MGI:5826467 +108168910 LOC108168910 - +108168911 Gm46831 MGI:MGI:5826468 +108168912 Gm46832 MGI:MGI:5826469 +108168913 Gm46833 MGI:MGI:5826470 +108168914 Gm46834 MGI:MGI:5826471 +108168915 Gm46835 MGI:MGI:5826472 +108168916 LOC108168916 - +108168917 LOC108168917 - +108168918 Gm46836 MGI:MGI:5826473 +108168919 Gm46837 MGI:MGI:5826474 +108168920 Gm37361 MGI:MGI:5610589 +108168921 Gm46838 MGI:MGI:5826475 +108168922 Gm46839 MGI:MGI:5826476 +108168923 Gm46840 MGI:MGI:5826477 +108168924 LOC108168924 - +108168925 Gm46841 MGI:MGI:5826478 +108168926 Gm46842 MGI:MGI:5826479 +108168927 LOC108168927 - +108168928 Gm46843 MGI:MGI:5826480 +108168929 Gm46844 MGI:MGI:5826481 +108168930 Gm46845 MGI:MGI:5826482 +108168931 Gm46846 MGI:MGI:5826483 +108168932 Gm46847 MGI:MGI:5826484 +108168933 LOC108168933 - +108168934 Gm46848 MGI:MGI:5826485 +108168935 Gm46849 MGI:MGI:5826486 +108168936 LOC108168936 - +108168937 Gm46850 MGI:MGI:5826487 +108168938 Gm46851 MGI:MGI:5826488 +108168939 Gm46852 MGI:MGI:5826489 +108168940 LOC108168940 - +108168941 Gm46853 MGI:MGI:5826490 +108168942 Gm46854 MGI:MGI:5826491 +108168943 Gm12721 MGI:MGI:3650292 +108168944 LOC108168944 - +108168945 LOC108168945 - +108168946 LOC108168946 - +108168947 LOC108168947 - +108168948 Gm46855 MGI:MGI:5826492 +108168949 Gm46856 MGI:MGI:5826493 +108168950 Gm46857 MGI:MGI:5826494 +108168951 LOC108168951 - +108168952 LOC108168952 - +108168953 Gm46858 MGI:MGI:5826495 +108168954 Gm12512 MGI:MGI:3651362 +108168955 LOC108168955 - +108168956 LOC108168956 - +108168957 Gm46859 MGI:MGI:5826496 +108168958 Gm46860 MGI:MGI:5826497 +108168959 LOC108168959 - +108168960 Gm45533 MGI:MGI:5791369 +108168961 Gm46861 MGI:MGI:5826498 +108168962 LOC108168962 - +108168963 Zfp978 MGI:MGI:3701123 +108168964 LOC108168964 - +108168965 Gm46862 MGI:MGI:5826499 +108168966 LOC108168966 - +108168967 Gm12648 MGI:MGI:3649948 +108168968 Gm46863 MGI:MGI:5826500 +108168969 Gm46864 MGI:MGI:5826501 +108168970 Gm46865 MGI:MGI:5826502 +108168971 Gm46866 MGI:MGI:5826503 +108168972 Gm46867 MGI:MGI:5826504 +108168973 Gm12828 MGI:MGI:3650145 +108168974 LOC108168974 - +108168975 Gm46868 MGI:MGI:5826505 +108168976 LOC108168976 - +108168977 Gm46869 MGI:MGI:5826506 +108168978 Gm46870 MGI:MGI:5826507 +108168979 LOC108168979 - +108168980 Gm46871 MGI:MGI:5826508 +108168981 Gm46872 MGI:MGI:5826509 +108168982 Gm46873 MGI:MGI:5826510 +108168983 Gm46874 MGI:MGI:5826511 +108168984 LOC108168984 - +108168985 Gm46875 MGI:MGI:5826512 +108168986 Gm46876 MGI:MGI:5826513 +108168987 LOC108168987 - +108168988 LOC108168988 - +108168989 Gm46877 MGI:MGI:5826514 +108168990 Gm46878 MGI:MGI:5826515 +108168991 Gm46879 MGI:MGI:5826516 +108168992 Gm46880 MGI:MGI:5826517 +108168993 Gm46881 MGI:MGI:5826518 +108168994 Gm46882 MGI:MGI:5826519 +108168995 Gm46883 MGI:MGI:5826520 +108168996 Gm46884 MGI:MGI:5826521 +108168997 Gm46885 MGI:MGI:5826522 +108168998 Gm46886 MGI:MGI:5826523 +108168999 Gm46887 MGI:MGI:5826524 +108169000 LOC108169000 - +108169001 LOC108169001 - +108169002 LOC108169002 - +108169003 Gm46888 MGI:MGI:5826525 +108169004 LOC108169004 - +108169005 Gm46889 MGI:MGI:5826526 +108169006 LOC108169006 - +108169007 Gm46890 MGI:MGI:5826527 +108169008 Gm46891 MGI:MGI:5826528 +108169009 LOC108169009 - +108169010 LOC108169010 Ensembl:ENSMUSG00000095779 +108169011 Gm46892 MGI:MGI:5826529 +108169012 Gm46893 MGI:MGI:5826530 +108169013 Gm46894 MGI:MGI:5826531 +108169014 Gm46895 MGI:MGI:5826532 +108169015 Gm46896 MGI:MGI:5826533 +108169016 Gm46897 MGI:MGI:5826534 +108169017 Gm46898 MGI:MGI:5826535 +108169018 Gm46899 MGI:MGI:5826536 +108169019 n-THgtg10 MGI:MGI:4413900 +108169020 LOC108169020 - +108169021 Gm46900 MGI:MGI:5826537 +108169022 LOC108169022 - +108169023 Gm46901 MGI:MGI:5826538 +108169024 Gm42834 MGI:MGI:5662971 +108169025 Gm43358 MGI:MGI:5663495 +108169026 Gm43132 MGI:MGI:5663269 +108169027 LOC108169027 - +108169028 LOC108169028 - +108169029 LOC108169029 - +108169030 Gm46902 MGI:MGI:5826539 +108169031 Gm46903 MGI:MGI:5826540 +108169032 Gm46904 MGI:MGI:5826541 +108169033 Gm46905 MGI:MGI:5826542 +108169034 Gm46906 MGI:MGI:5826543 +108169035 Gm16288 MGI:MGI:3826608 +108169036 Gm46907 MGI:MGI:5826544 +108169037 Gm46908 MGI:MGI:5826545 +108169038 Gm46909 MGI:MGI:5826546 +108169039 LOC108169039 Ensembl:ENSMUSG00000085166 +108169040 Gm42935 MGI:MGI:5663072 +108169041 Gm46910 MGI:MGI:5826547 +108169042 Gm43700 MGI:MGI:5663837 +108169043 Gm46911 MGI:MGI:5826548 +108169044 Gm46912 MGI:MGI:5826549 +108169045 Gm46913 MGI:MGI:5826550 +108169046 Gm46914 MGI:MGI:5826551 +108169047 Gm15477 MGI:MGI:3705209 +108169048 LOC108169048 - +108169049 LOC108169049 - +108169050 LOC108169050 - +108169051 LOC108169051 - +108169052 LOC108169052 - +108169053 LOC108169053 - +108169054 Gm46915 MGI:MGI:5826552 +108169055 LOC108169055 - +108169056 Gm46916 MGI:MGI:5826553 +108169057 Gm46917 MGI:MGI:5826554 +108169058 LOC108169058 - +108169059 LOC108169059 - +108169060 LOC108169060 - +108169061 Gm46918 MGI:MGI:5826555 +108169062 LOC108169062 - +108169063 Gm43247 MGI:MGI:5663384 +108169064 Gm46919 MGI:MGI:5826556 +108169065 Gm46920 MGI:MGI:5826557 +108169066 LOC108169066 - +108169067 Gm46921 MGI:MGI:5826558 +108169068 Gm46922 MGI:MGI:5826559 +108169069 Gm16001 MGI:MGI:3802119|Ensembl:ENSMUSG00000085433 +108169070 Gm46923 MGI:MGI:5826560 +108169071 Gm43001 MGI:MGI:5663138 +108169072 LOC108169072 - +108169073 Gm15921 MGI:MGI:3801933 +108169074 Gm46924 MGI:MGI:5826561 +108169075 Gm46925 MGI:MGI:5826562 +108169076 LOC108169076 - +108169077 LOC108169077 - +108169078 Gm46926 MGI:MGI:5826563 +108169079 Gm46927 MGI:MGI:5826564 +108169080 Gm42808 MGI:MGI:5662945 +108169081 Gm17135 MGI:MGI:4937962 +108169082 LOC108169082 Ensembl:ENSMUSG00000097228 +108169083 Gm46928 MGI:MGI:5826565 +108169084 Gm46929 MGI:MGI:5826566 +108169085 LOC108169085 - +108169086 Gm42529 MGI:MGI:5662666 +108169087 Gm46930 MGI:MGI:5826567 +108169088 Gm46931 MGI:MGI:5826568 +108169089 Gm15546 MGI:MGI:3782995 +108169090 LOC108169090 - +108169091 LOC108169091 - +108169092 Gm42580 MGI:MGI:5662717 +108169093 Gm43828 MGI:MGI:5663965 +108169094 Gm46932 MGI:MGI:5826569 +108169095 Gm43028 MGI:MGI:5663165 +108169096 Gm46933 MGI:MGI:5826570 +108169097 LOC108169097 Ensembl:ENSMUSG00000094195|Vega:OTTMUSG00000055727 +108169098 Gm46934 MGI:MGI:5826571 +108169099 LOC108169099 - +108169100 LOC108169100 Ensembl:ENSMUSG00000092166 +108169101 Gm46935 MGI:MGI:5826572 +108169102 Gm42627 MGI:MGI:5662764 +108169103 Gm43649 MGI:MGI:5663786 +108169104 Gm46936 MGI:MGI:5826573 +108169105 LOC108169105 - +108169106 Gm43117 MGI:MGI:5663254 +108169107 Gm46937 MGI:MGI:5826574 +108169108 Gm43044 MGI:MGI:5663181 +108169109 LOC108169109 - +108169110 Gm46938 MGI:MGI:5826575 +108169111 Gm43217 MGI:MGI:5663354 +108169112 LOC108169112 - +108169113 Gm46939 MGI:MGI:5826576 +108169114 Gm46940 MGI:MGI:5826577 +108169115 Gm46941 MGI:MGI:5826578 +108169116 Gm46942 MGI:MGI:5826579 +108169117 LOC108169117 - +108169118 Gm46943 MGI:MGI:5826580 +108169119 Gm46944 MGI:MGI:5826581 +108169120 LOC108169120 - +108169121 Gm46945 MGI:MGI:5826582 +108169122 Gm43772 MGI:MGI:5663909 +108169123 Gm46946 MGI:MGI:5826583 +108169124 Gm20548 MGI:MGI:5142013 +108169125 Gm46947 MGI:MGI:5826584 +108169126 n-TDgtc1 MGI:MGI:4413752 +108169127 Gm46948 MGI:MGI:5826585 +108169128 Gm46949 MGI:MGI:5826586 +108169129 Gm46950 MGI:MGI:5826587 +108169130 Gm46951 MGI:MGI:5826588 +108169131 Gm46952 MGI:MGI:5826589 +108169132 Gm46953 MGI:MGI:5826590 +108169133 Gm42573 MGI:MGI:5662710 +108169134 Gm46954 MGI:MGI:5826591 +108169135 LOC108169135 - +108169136 Gm46955 MGI:MGI:5826592 +108169137 Gm46956 MGI:MGI:5826593 +108169138 Gm46957 MGI:MGI:5826594 +108169139 Gm46958 MGI:MGI:5826595 +108169140 Gm44764 MGI:MGI:5753340 +108169141 Gm46959 MGI:MGI:5826596 +108169142 Gm46960 MGI:MGI:5826597 +108169143 LOC108169143 - +108169144 LOC108169144 - +108169145 Gm44026 MGI:MGI:5690418 +108169146 LOC108169146 - +108169147 LOC108169147 - +108169148 Gm46961 MGI:MGI:5826598 +108169149 Gm46962 MGI:MGI:5826599 +108169150 Gm46963 MGI:MGI:5826600 +108169151 Gm46964 MGI:MGI:5826601 +108169152 Gm46965 MGI:MGI:5826602 +108169153 Gm46966 MGI:MGI:5826603 +108169154 Gm20426 MGI:MGI:5141891 +108169155 Gm46967 MGI:MGI:5826604 +108169156 Gm44803 MGI:MGI:5753379 +108169157 Gm46968 MGI:MGI:5826605 +108169158 Gm46969 MGI:MGI:5826606 +108169159 Gm46970 MGI:MGI:5826607 +108169160 LOC108169160 - +108169161 Gm46971 MGI:MGI:5826608 +108169162 Gm46972 MGI:MGI:5826609 +108169163 Gm20404 MGI:MGI:5141869 +108169164 Gm46973 MGI:MGI:5826610 +108169165 Gm44173 MGI:MGI:5690565 +108169166 Gm44184 MGI:MGI:5690576 +108169167 Gm46974 MGI:MGI:5826611 +108169168 Gm46975 MGI:MGI:5826612 +108169169 Gm46976 MGI:MGI:5826613 +108169170 Klra11-ps MGI:MGI:1321092 +108169171 Gm46977 MGI:MGI:5826614 +108169172 Gm46978 MGI:MGI:5826615 +108169173 Gm25136 MGI:MGI:5454913 +108169174 Gm44140 MGI:MGI:5690532 +108169175 LOC108169175 - +108169176 Gm46979 MGI:MGI:5826616 +108169177 Gm46980 MGI:MGI:5826617 +108169178 Gm46981 MGI:MGI:5826618 +108169179 LOC108169179 - +108169180 Gm44163 MGI:MGI:5690555 +108169181 LOC108169181 - +108169182 Gm46982 MGI:MGI:5826619 +108169183 LOC108169183 - +108169184 Gm43975 MGI:MGI:5690367 +108169185 Gm43978 MGI:MGI:5690370 +108169186 Gm43979 MGI:MGI:5690371 +108169187 Gm44003 MGI:MGI:5690395 +108169188 Gm46983 MGI:MGI:5826620 +108169189 Gm46984 MGI:MGI:5826621 +108169190 Gm46985 MGI:MGI:5826622 +108169191 Gm44083 MGI:MGI:5690475 +108169192 LOC108169192 - +108169193 Gm44768 MGI:MGI:5753344 +108169194 Gm43309 MGI:MGI:5663446 +108169195 Gm46986 MGI:MGI:5826623 +108169196 Gm44336 MGI:MGI:5690728 +108169197 LOC108169197 - +108169198 Gm44431 MGI:MGI:5690823 +108169199 Gm43124 MGI:MGI:5663261 +108169200 Gm46987 MGI:MGI:5826624 +108169201 Gm46988 MGI:MGI:5826625 +108169202 Gm46989 MGI:MGI:5826626 +108169203 Gm46990 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- +3338897 COX2 - +3338898 Trnl2 - +3338899 ND4 - +3338900 ATP8 - +3338901 Trns2 - +3338902 ND1 - +3338903 ND4L - +3338904 Trns1 - +3338905 Trnl1 - +5912275 ND5 - +5912276 ND4 - +5912277 CYTB - +5912278 ND2 - +5912279 ND4L - +5912280 COX3 - +5912281 COX2 - +5912282 ATP6 - +5912283 ND6 - +5912284 ATP8 - +5912285 ND3 - +5912286 COX1 - +5912287 ND1 - +3337205 COX1 - +3337206 COX3 - +3337207 ATP6 - +3337208 CYTB - +3337209 COX2 - +3337210 ND4 - +3337211 ND4L - +3337212 ND5 - +3337213 ND3 - +3337214 ND1 - +3337215 ND6 - +3337216 ATP8 - +3337217 ND2 - diff --git a/resources/resource_v1.0.1.txt b/resources/resource_v1.0.1.txt new file mode 100644 index 0000000..e69de29 diff --git a/resources/web/contact.html b/resources/web/contact.html index 62407a5..4026a5e 100644 --- a/resources/web/contact.html +++ b/resources/web/contact.html @@ -51,7 +51,7 @@
Contact: - If you want to contact us to report a problem we recommend you to visit our website http://app.tappas.org/contact or send an email to pedsalga@upv.edu.es. + If you want to contact us to report a problem we recommend you to visit our website http://app.tappas.org/contact or send an email to pedsalga@upv.edu.es relative to tappAS installation or errors or to angeles.arzalluz@gmail.com for tappAS functionality.
diff --git a/resources/webFiles.txt~ b/resources/webFiles.txt~ new file mode 100644 index 0000000..05a4f5f --- /dev/null +++ b/resources/webFiles.txt~ @@ -0,0 +1,9 @@ +appOverview.html +css/web.css +scripts/ebook.js +scripts/maps.js +scripts/overview.js +scripts/scripts.js +scripts/slides.js +images/appLayout.png + diff --git a/scripts/DFI.R b/scripts/DFI.R index dd3e40a..ad34b12 100644 --- a/scripts/DFI.R +++ b/scripts/DFI.R @@ -580,146 +580,128 @@ if(len_zero & cont_err == cont){ lstProtein = strsplit(proteinFeatures, ",") dfi_total_count=read.table(file.path(inFileCount), sep="\t", header=TRUE, stringsAsFactors = F) - cat("\n1111. DFI_matrix original") - cat(as.character(head(result_dfi))) - cat("\n") - - saveRDS(result_dfi, file = "D:/Pedro/Trabajo/CIPF/tappAS/tappasWorkspace/Projects/Project.0655359829.tappas/Data/DFI/my_data.rds") - - cat("\nBuilding P-Values tables...") - dfi_matrix = unique(result_dfi[,c("gene","qValue")]) - dfi_matrix$Feature = sapply(dfi_matrix$gene, getFeatureName) - dfi_matrix$Gene = sapply(dfi_matrix$gene, getGeneName) - dfi_matrix$DFI = ifelse(as.numeric(levels(dfi_matrix$qValue))[dfi_matrix$qValue]<=sig, "DFI", "Not DFI") - - cat("\n2222. DFI_matrix original") - cat(as.character(head(dfi_matrix))) - cat("\n") - - dfi_results = data.frame() - for(feature in unique(dfi_matrix$Feature)){ - newRow = data.frame(Feature=feature, - TotalCount=nrow(dfi_matrix[dfi_matrix$Feature==feature,]), - DFICount=nrow(dfi_matrix[dfi_matrix$Feature==feature & dfi_matrix$DFI == "DFI",]), - TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$Total), - Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), - Time="0") - dfi_results = rbind(dfi_results,newRow) - } - - cat("\3333. DFI_Results primera tabla") - cat(as.character(dfi_results)) - cat("\n") - - dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 - dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 - dfi_results$Feature = as.character(dfi_results$Feature) - dfi_results = dfi_results[order(dfi_results$Feature, method = ),] - - ######### - # TEST1 # - ######### - - # feature level - result_utrmotif = NULL - for(x in unique(dfi_results$Feature)){ - xDFI = dfi_results[dfi_results$Feature==x,]$DFICount - xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI - allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) - allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI - - tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) - colnames(tbDFI) <- c("DFI","ANNOT-DFI") - rownames(tbDFI) <- c("X","ALL") - tbDFI <- as.table(tbDFI) - - result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) - } - result_utrmotif_df = data.frame(result_utrmotif, stringsAsFactors = F) - result_utrmotif_df$X2 = as.numeric(result_utrmotif_df$X2) - result_utrmotif_df$adj = p.adjust(result_utrmotif_df$X2, method = "hochberg") - result_utrmotif_df = result_utrmotif_df[order(result_utrmotif_df$X1),] - colnames(result_utrmotif_df) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") - result_utrmotif_df$`P-Value` = signif(result_utrmotif_df$`P-Value`, digits = 5) - result_utrmotif_df$`Adj.P-Value` = signif(result_utrmotif_df$`Adj.P-Value`, digits = 5) - - cat("\4444. DFI_Results segunda tabla") - cat(as.character(result_utrmotif_df)) - cat("\n") - - ############## - # SAVE TESTS # - ############## - - write.table(result_utrmotif_df, file = outputTestFeatures, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") - - ######### - # TEST2 # - ######### - - # gene level - cat("\nWriting DFI Test2 file...\n") + cat("\nBuilding P-Values tables...") + dfi_matrix = unique(result_dfi[,c("gene","qValue")]) + dfi_matrix$Feature = sapply(dfi_matrix$gene, getFeatureName) + dfi_matrix$Gene = sapply(dfi_matrix$gene, getGeneName) + dfi_matrix$DFI = ifelse(as.numeric(levels(dfi_matrix$qValue))[dfi_matrix$qValue]<=sig, "DFI", "Not DFI") + + dfi_results = data.frame() + for(feature in unique(dfi_matrix$Feature)){ + newRow = data.frame(Feature=feature, + TotalCount=nrow(dfi_matrix[dfi_matrix$Feature==feature,]), + DFICount=nrow(dfi_matrix[dfi_matrix$Feature==feature & dfi_matrix$DFI == "DFI",]), + TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$Total), + Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), + Time="0") + dfi_results = rbind(dfi_results,newRow) + } - res_genes = NULL - dfi_matrix_genes = unique(dfi_matrix[,c("Gene","Feature","DFI")]) - for(gene in unique(dfi_matrix_genes$Gene)){ - for(feature in unique(dfi_matrix_genes[dfi_matrix_genes$Gene == gene,]$Feature)){ - submatrix = dfi_matrix_genes[dfi_matrix_genes$Gene == gene & dfi_matrix_genes$Feature == feature,] - if(nrow(submatrix)>1) #a DFI and Not DFI - res_genes = rbind(res_genes, submatrix[submatrix$DFI == "DFI",]) - else - res_genes = rbind(res_genes, submatrix) + dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 + dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 + dfi_results$Feature = as.character(dfi_results$Feature) + dfi_results = dfi_results[order(dfi_results$Feature, method = ),] + + ######### + # TEST1 # + ######### + + # feature level + result_utrmotif = NULL + for(x in unique(dfi_results$Feature)){ + xDFI = dfi_results[dfi_results$Feature==x,]$DFICount + xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI + allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) + allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI + + tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) + colnames(tbDFI) <- c("DFI","ANNOT-DFI") + rownames(tbDFI) <- c("X","ALL") + tbDFI <- as.table(tbDFI) + + result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) + } + result_utrmotif_df = data.frame(result_utrmotif, stringsAsFactors = F) + result_utrmotif_df$X2 = as.numeric(result_utrmotif_df$X2) + result_utrmotif_df$adj = p.adjust(result_utrmotif_df$X2, method = "hochberg") + result_utrmotif_df = result_utrmotif_df[order(result_utrmotif_df$X1),] + colnames(result_utrmotif_df) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") + result_utrmotif_df$`P-Value` = signif(result_utrmotif_df$`P-Value`, digits = 5) + result_utrmotif_df$`Adj.P-Value` = signif(result_utrmotif_df$`Adj.P-Value`, digits = 5) + + ############## + # SAVE TESTS # + ############## + + write.table(result_utrmotif_df, file = outputTestFeatures, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") + + ######### + # TEST2 # + ######### + + # gene level + cat("\nWriting DFI Test2 file...\n") + + res_genes = NULL + dfi_matrix_genes = unique(dfi_matrix[,c("Gene","Feature","DFI")]) + for(gene in unique(dfi_matrix_genes$Gene)){ + for(feature in unique(dfi_matrix_genes[dfi_matrix_genes$Gene == gene,]$Feature)){ + submatrix = dfi_matrix_genes[dfi_matrix_genes$Gene == gene & dfi_matrix_genes$Feature == feature,] + if(nrow(submatrix)>1) #a DFI and Not DFI + res_genes = rbind(res_genes, submatrix[submatrix$DFI == "DFI",]) + else + res_genes = rbind(res_genes, submatrix) + } } - } - dfi_results = data.frame() - for(feature in unique(res_genes$Feature)){ - newRow = data.frame(Feature=feature, - TotalCount=nrow(res_genes[res_genes$Feature==feature,]), - DFICount=nrow(res_genes[res_genes$Feature==feature & res_genes$DFI == "DFI",]), - TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$ByGenes), - Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), - Time="0") - dfi_results = rbind(dfi_results,newRow) - } + dfi_results = data.frame() + for(feature in unique(res_genes$Feature)){ + newRow = data.frame(Feature=feature, + TotalCount=nrow(res_genes[res_genes$Feature==feature,]), + DFICount=nrow(res_genes[res_genes$Feature==feature & res_genes$DFI == "DFI",]), + TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$ByGenes), + Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), + Time="0") + dfi_results = rbind(dfi_results,newRow) + } - dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 - dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 - dfi_results$Feature = as.character(dfi_results$Feature) - dfi_results = dfi_results[order(dfi_results$Feature, method = ),] - - ######### - # TEST2 # - ######### - - # gene level - result_utrmotif = NULL - for(x in unique(dfi_results$Feature)){ - xDFI = dfi_results[dfi_results$Feature==x,]$DFICount - xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI - allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) - allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI - - tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) - colnames(tbDFI) <- c("DFI","ANNOT-DFI") - rownames(tbDFI) <- c("X","ALL") - tbDFI <- as.table(tbDFI) - - result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) - } - result_utrmotif_gene = data.frame(result_utrmotif, stringsAsFactors = F) - result_utrmotif_gene$X2 = as.numeric(result_utrmotif_gene$X2) - result_utrmotif_gene$adj = p.adjust(result_utrmotif_gene$X2, method = "hochberg") - result_utrmotif_gene = result_utrmotif_gene[order(result_utrmotif_gene$X1),] - colnames(result_utrmotif_gene) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") - result_utrmotif_gene$`P-Value` = signif(result_utrmotif_gene$`P-Value`, digits = 5) - result_utrmotif_gene$`Adj.P-Value` = signif(result_utrmotif_gene$`Adj.P-Value`, digits = 5) - - ############## - # SAVE TESTS # - ############## - - write.table(result_utrmotif_gene, file = outputTestGenes, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") + dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 + dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 + dfi_results$Feature = as.character(dfi_results$Feature) + dfi_results = dfi_results[order(dfi_results$Feature, method = ),] + + ######### + # TEST2 # + ######### + + # gene level + result_utrmotif = NULL + for(x in unique(dfi_results$Feature)){ + xDFI = dfi_results[dfi_results$Feature==x,]$DFICount + xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI + allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) + allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI + + tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) + colnames(tbDFI) <- c("DFI","ANNOT-DFI") + rownames(tbDFI) <- c("X","ALL") + tbDFI <- as.table(tbDFI) + + result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) + } + result_utrmotif_gene = data.frame(result_utrmotif, stringsAsFactors = F) + result_utrmotif_gene$X2 = as.numeric(result_utrmotif_gene$X2) + result_utrmotif_gene$adj = p.adjust(result_utrmotif_gene$X2, method = "hochberg") + result_utrmotif_gene = result_utrmotif_gene[order(result_utrmotif_gene$X1),] + colnames(result_utrmotif_gene) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") + result_utrmotif_gene$`P-Value` = signif(result_utrmotif_gene$`P-Value`, digits = 5) + result_utrmotif_gene$`Adj.P-Value` = signif(result_utrmotif_gene$`Adj.P-Value`, digits = 5) + + ############## + # SAVE TESTS # + ############## + + write.table(result_utrmotif_gene, file = outputTestGenes, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") cat("\nAll done.\n") } diff --git a/scripts/DFI_TimeCourse.R b/scripts/DFI_TimeCourse.R index cb64b1b..b9c0817 100644 --- a/scripts/DFI_TimeCourse.R +++ b/scripts/DFI_TimeCourse.R @@ -556,7 +556,7 @@ Favored_tappas <- function(exp, design) args = commandArgs(TRUE) cat("Differential Feature Inclusion Analysis script arguments: ", args, "\n") arglen = length(args) -if(arglen != 14) +if(arglen != 17) stop("Invalid number of arguments.") method = "" indir = "" @@ -575,7 +575,7 @@ outputTestGenes = "" analysisId = "" indirDFI = "" -for(i in 1:14) { +for(i in 1:17) { if(length(grep("^-m", args[i])) > 0) method = substring(args[i], 3) else if(length(grep("^-i", args[i])) > 0) @@ -604,12 +604,18 @@ for(i in 1:14) { outputTestGenes = substring(args[i], 4) else if(length(grep("^-a", args[i])) > 0) analysisId = substring(args[i], 3) + else if(length(grep("^-lt", args[i])) > 0) + transFeatures = substring(args[i], 4) + else if(length(grep("^-lp", args[i])) > 0) + proteinFeatures = substring(args[i], 4) + else if(length(grep("^-x", args[i])) > 0) + dfiMatrixTest = substring(args[i], 3) else { cat("Invalid command line argument: '", args[i], "'\n") stop("Invalid command line argument.") } } -if(nchar(indirDFI) == 0 || nchar(analysisId) == 0 || nchar(outputTestFeatures) == 0 || nchar(outputTestGenes) == 0 || nchar(inFileCount) == 0 || nchar(sig) == 0 || nchar(outdir) == 0 || nchar(indir) == 0 || nchar(method) == 0 || nchar(degValue) == 0 || nchar(restrictType) == 0 || nchar(cmpType) == 0 || nchar(filterFC) == 0 || nchar(filteringType) == 0) +if(nchar(dfiMatrixTest) == 0 || nchar(transFeatures) == 0 || nchar(proteinFeatures) == 0 || nchar(indirDFI) == 0 || nchar(analysisId) == 0 || nchar(outputTestFeatures) == 0 || nchar(outputTestGenes) == 0 || nchar(inFileCount) == 0 || nchar(sig) == 0 || nchar(outdir) == 0 || nchar(indir) == 0 || nchar(method) == 0 || nchar(degValue) == 0 || nchar(restrictType) == 0 || nchar(cmpType) == 0 || nchar(filterFC) == 0 || nchar(filteringType) == 0) stop("Missing command line argument.") #### determine what type of data to run DIU for @@ -678,7 +684,6 @@ for(db in sources$db) { dbcatGenes[,1] <- NULL cat("\nRead ", nrow(dbcatGenes), " feature id map data rows") #print(head(dbcatGenes)) - ### filter matrix cat("\nRead ", nrow(dbcatMatrix), " expression data rows") @@ -799,12 +804,156 @@ if(len_zero & cont == 0){ write.table(result_dfi, file.path(outdir, paste0("dfi_result.",as.character(analysisId),".tsv")), quote=FALSE, row.names=FALSE, sep="\t") # write completion file - cat("\nWriting DFInalysis completed file...") + cat("\nWriting DFI Analysis completed file...") filedone <- file(file.path(outdir, paste0("done.",as.character(analysisId),".txt"))) writeLines("done", filedone) close(filedone) - + + # write sub dfiMatrixTest (subversion just to get PValues in tables) + cat("\nWriting DFI Sub-Matrix file...") + getGeneName <- function(x){ + res <- strsplit(as.character(x),";")[[1]][1] + return(res) + } + + getFeatureName <- function(x){ + res <- strsplit(as.character(x),";")[[1]][3] + return(res) + } + + ## TESTS + + lstTrans = strsplit(transFeatures, ",") + lstProtein = strsplit(proteinFeatures, ",") + dfi_total_count=read.table(file.path(inFileCount), sep="\t", header=TRUE, stringsAsFactors = F) + + cat("\nBuilding P-Values tables...") + dfi_matrix = unique(result_dfi[,c("gene","adjPValue")]) + dfi_matrix$Feature = sapply(dfi_matrix$gene, getFeatureName) + dfi_matrix$Gene = sapply(dfi_matrix$gene, getGeneName) + + #dfi_matrix$DFI = ifelse(as.numeric(levels(dfi_matrix$adjPValue))[dfi_matrix$adjPValue]<=sig, "DFI", "Not DFI") + dfi_matrix$DFI = ifelse(dfi_matrix$adjPValue<=sig, "DFI", "Not DFI") + + dfi_results = data.frame() + for(feature in unique(dfi_matrix$Feature)){ + newRow = data.frame(Feature=feature, + TotalCount=nrow(dfi_matrix[dfi_matrix$Feature==feature,]), + DFICount=nrow(dfi_matrix[dfi_matrix$Feature==feature & dfi_matrix$DFI == "DFI",]), + TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$Total), + Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), + Time="0") + dfi_results = rbind(dfi_results,newRow) + } + + dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 + dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 + dfi_results$Feature = as.character(dfi_results$Feature) + dfi_results = dfi_results[order(dfi_results$Feature, method = ),] + + ######### + # TEST1 # + ######### + + # feature level + result_utrmotif = NULL + for(x in unique(dfi_results$Feature)){ + xDFI = dfi_results[dfi_results$Feature==x,]$DFICount + xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI + allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) + allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI + + tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) + colnames(tbDFI) <- c("DFI","ANNOT-DFI") + rownames(tbDFI) <- c("X","ALL") + tbDFI <- as.table(tbDFI) + + result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) + } + result_utrmotif_df = data.frame(result_utrmotif, stringsAsFactors = F) + result_utrmotif_df$X2 = as.numeric(result_utrmotif_df$X2) + result_utrmotif_df$adj = p.adjust(result_utrmotif_df$X2, method = "hochberg") + result_utrmotif_df = result_utrmotif_df[order(result_utrmotif_df$X1),] + colnames(result_utrmotif_df) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") + result_utrmotif_df$`P-Value` = signif(result_utrmotif_df$`P-Value`, digits = 5) + result_utrmotif_df$`Adj.P-Value` = signif(result_utrmotif_df$`Adj.P-Value`, digits = 5) + + ############## + # SAVE TESTS # + ############## + + write.table(result_utrmotif_df, file = outputTestFeatures, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") + + ######### + # TEST2 # + ######### + + # gene level + cat("\nWriting DFI Test2 file...\n") + + res_genes = NULL + dfi_matrix_genes = unique(dfi_matrix[,c("Gene","Feature","DFI")]) + for(gene in unique(dfi_matrix_genes$Gene)){ + for(feature in unique(dfi_matrix_genes[dfi_matrix_genes$Gene == gene,]$Feature)){ + submatrix = dfi_matrix_genes[dfi_matrix_genes$Gene == gene & dfi_matrix_genes$Feature == feature,] + if(nrow(submatrix)>1) #a DFI and Not DFI + res_genes = rbind(res_genes, submatrix[submatrix$DFI == "DFI",]) + else + res_genes = rbind(res_genes, submatrix) + } + } + + dfi_results = data.frame() + for(feature in unique(res_genes$Feature)){ + newRow = data.frame(Feature=feature, + TotalCount=nrow(res_genes[res_genes$Feature==feature,]), + DFICount=nrow(res_genes[res_genes$Feature==feature & res_genes$DFI == "DFI",]), + TotalAnnot=sum(dfi_total_count[dfi_total_count$Feature==feature,]$ByGenes), + Level=ifelse(feature %in% lstTrans, "Transcript","Protein"), + Time="0") + dfi_results = rbind(dfi_results,newRow) + } + + dfi_results["Freq1"] = dfi_results[,"TotalCount"]/sum(dfi_results[,"TotalCount"])*100 + dfi_results["Freq2"] = dfi_results[,"TotalAnnot"]/sum(dfi_results[,"TotalAnnot"])*100 + dfi_results$Feature = as.character(dfi_results$Feature) + dfi_results = dfi_results[order(dfi_results$Feature, method = ),] + + ######### + # TEST2 # + ######### + + # gene level + result_utrmotif = NULL + for(x in unique(dfi_results$Feature)){ + xDFI = dfi_results[dfi_results$Feature==x,]$DFICount + xANNOT = dfi_results[dfi_results$Feature==x,]$TotalAnnot-xDFI + allDFI = sum(dfi_results[dfi_results$Feature!=x,]$DFICount) + allANNOT = sum(dfi_results[dfi_results$Feature!=x, ]$TotalAnnot)-allDFI + + tbDFI <- matrix(c(xDFI,xANNOT,allDFI,allANNOT),ncol=2,byrow=TRUE) + colnames(tbDFI) <- c("DFI","ANNOT-DFI") + rownames(tbDFI) <- c("X","ALL") + tbDFI <- as.table(tbDFI) + + result_utrmotif = rbind(result_utrmotif, c(x,fisher.test(x = tbDFI, alternative="less")$p.value, as.character(tbDFI))) + } + result_utrmotif_gene = data.frame(result_utrmotif, stringsAsFactors = F) + result_utrmotif_gene$X2 = as.numeric(result_utrmotif_gene$X2) + result_utrmotif_gene$adj = p.adjust(result_utrmotif_gene$X2, method = "hochberg") + result_utrmotif_gene = result_utrmotif_gene[order(result_utrmotif_gene$X1),] + colnames(result_utrmotif_gene) = c("Feature","P-Value","feat_DFI","all_DFI","feat_ANNOT-DFI","all_ANNOT-DFI", "Adj.P-Value") + result_utrmotif_gene$`P-Value` = signif(result_utrmotif_gene$`P-Value`, digits = 5) + result_utrmotif_gene$`Adj.P-Value` = signif(result_utrmotif_gene$`Adj.P-Value`, digits = 5) + + ############## + # SAVE TESTS # + ############## + + write.table(result_utrmotif_gene, file = outputTestGenes, quote = FALSE, col.names = TRUE, row.names = FALSE, sep = "\t") + + cat("\nAll done.\n") cat("\nAll done.\n")